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+s1cc(cc1C12N=C(N)N(C)C(=O)C1CN(C2)C(=O)c1ccccc1)-c1cc(ccc1)C#N +s1cc(cc1C12N=C(N)N(C)C(=O)C1CN(C2)c1ncccc1OC)-c1cc(ccc1)C#N +S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)NC(C(O)CC(OCCOC)C(=O)NC(C(C)C)C(=O)NCc1ccccc1)COc1cc(F)cc(F)c1)C(=O)NC(C)c1ccccc1)C +O=C1N(C)C(=[NH2+])NC1(C1CC1)c1cc(ccc1)-c1cc(cnc1)C#CC +s1cc(cc1C12N=C(N)N(C)C(=O)C1CN(C2)c1ncccc1C#N)-c1cc(ccc1)C#N +O=C(c1cc2CN(CCC(=O)N(C)C3CCCCC3)C(=[NH+]c2cc1)N)c1ccccc1 +S1(=O)(=O)N(c2cc(cc3n(cc(CC1)c23)CC)C(=O)NC(Cc1ccccc1)C(O)(O)C[NH2+]C1CCOCC1)C +Clc1cc(cc(C)c1NC(=O)C)CN\C(=N/C(=O)c1c(nsc1C)-c1ccc(OC)cc1)\N +S(=O)(=O)(N(C)c1cc(cc(c1)C(=O)NC(Cc1ccccc1)C[NH2+]C(C(O)C)C(=O)NCC(C)C)C(=O)NC(C)c1ccccc1)C +O1CCCCCCNC(=O)CC(NC(=O)C(NC1=O)C(C)C)C(=O)NC(C(O)CC(C(=O)NC(C(C)C)C(=O)NCc1ccccc1)C)CC(C)C +Fc1ccc(NC(=O)C(CC([NH3+])C(NC(=O)c2cc(ccc2)C(=O)N(CCC)CCC)Cc2ccccc2)C)cc1 +Fc1c2c(ccc1)C([NH+]=C2N)(c1cc(ccc1)-c1cncnc1)c1cc(ncc1)C(F)F +Clc1cc(cc(Cl)c1N)CN\C(=N/C(=O)c1c(nsc1C)-c1ccc(OC)cc1)\N +s1cc(cc1C1(N=C(N)N(C)C(=O)C1)C)-c1cc(ccc1)C#N 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+S(=O)(=O)(N(C)c1cc2cc(NCCCCOc3cc(CC(NC2=O)C(O)C[NH2+]C2(CC2)c2cc(ccc2)C(C)C)ccc3)c1)CCC +S1(=O)(=O)CC(Cc2cc(OC(C(F)(F)F)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 +S1(=O)(=O)CC(Cc2cc(O[C@H](COC)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 +S1(=O)(=O)CC(Cc2cc(OC(C(F)(F)F)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(O)(C)C)C1 +S1(=O)(=O)CC(Cc2cc(OC(C(F)(F)F)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(CO)(C)C)C1 +Fc1ccc(cc1OC(F)(F)F)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +FC(F)(F)c1cc(ccc1)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1ccc(cc1C#N)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1c2c(ccc1)C(N=C2N)(C=1C=C(C)C(=O)N(C=1)CC)c1cc(NC(=O)c2ncccc2)ccc1 +O=C(NCC1CCCCC1)C(Cc1cc2cc(ccc2nc1N)-c1ccccc1C)C +O1c2c(cc(cc2)CC)C([NH2+]CC(O)C2NC(=O)C=3C=C(N4CCCC4)C(=O)N(CCCCc4cc(C2)ccc4)C=3)CC12CCC2 +Fc1c2c(cc(F)c1)C(N=C2N)(C=1C=C(C)C(=O)N(C=1)CC)c1cc(ccc1)-c1cc(cnc1)C#CC 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+FC(F)Oc1ccc(cc1C)[C@@]1(N=C(N)N(C)C1=O)c1ccccc1 +Fc1ccc(cc1-c1cncnc1)C1(N=C(N)N(C)C1=O)c1cn(nc1)C(C)C +s1cc(cc1CC)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cncnc1 +Clc1scc(c1)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cncnc1 +S1(=O)CC(Cc2cc(OC(COC)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(OC(C)C)ccc2)C1 +Fc1cc(cc(F)c1)CC(NC(=O)c1c2cccnc2n(c1)C(=O)N(CCCC)C)C(O)C[NH2+]C1(CC1)c1cc(ccc1)CC +O1CCCCOc2nc(cc(c2)C(=O)NC(Cc2cc1ccc2)C(O)C[NH2+]C(C)c1cc(ccc1)C(C)C)C +s1ccnc1NC1CCC([NH2+]CC(O)C(NC(=O)C)Cc2cc(F)cc(F)c2)(CC1)c1cc(ccc1)C(C)(C)C +S1(Oc2cc(cc3c2n(cc3CC)CC1)C(=O)NC([C@H](O)C[NH2+]CC1CCOCC1)Cc1ccccc1)(=O)=O +Fc1c2c(ccc1)C(N=C2N)(c1cc(ccc1)-c1cncnc1)c1cc(ncc1)C1CC1 +FC(F)(F)c1cc(ccc1)C[NH2+]CC(O)C(NC(=O)c1cc(N2CCCC2=O)c2occ(c2c1)CC)Cc1ccccc1 +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(CCCC)C1=O)C)C(O)C1[NH2+]CC(OCCC)C1 +FC1(F)COC(=NC1(C)c1cc(NC(=O)c2ncc(cc2)C)ccc1F)N +Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCCCC1)c1cc(ccc1)C1CCOC1 +O=C(NCc1cccnc1)C(Cc1cc2cc(ccc2nc1N)-c1ccccc1C)C +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(CC(C)C)C1=O)C)C(O)C[NH2+]Cc1cc(OC)ccc1 +Fc1c(cccc1OC)-c1cc(ccc1)C1(N=C(N2C1=NCCC2)N)c1ccncc1 +S1(=O)(=O)N(CCCC1)c1cc(cc(c1)C(=O)N[C@H]([C@@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1cc(F)cc(F)c1)C(=O)C +O(C)c1cc(ccc1OC)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1 +O1CCOc2c1cc(cc2)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1 +FC(F)Oc1ccc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)CCC +FC(F)Oc1ccc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)CCCCC +FC(F)Oc1ccc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)\C=C\C1CC1 +s1cc(cc1)C1(N=C(N)N(C)C1=O)c1cc(-c2cccnc2)c(F)cc1 +s1cc(cc1)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1nccnc1 +S1(=O)(=O)N(CCCC1)c1cc(cc(NCC)c1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C1CCOCC1 +S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)C1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C)C +O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)C)Cc2ccccc2)CC12CCC2)CC +O(C)c1ccc(cc1)C1(N=C(N2C1=NCCC2)N)c1cc(ccc1)-c1cccnc1 +Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCc2nc(ncc2C1)C)c1cc(ccc1)C(C)(C)C +S(=O)(=O)(Nc1cc(cc(c1)C(C)(C)C)C1([NH2+]CC(O)C(NC(=O)C)Cc2cc(F)cc(F)c2)CCCCC1)C +S1(=O)(=O)CC(Cc2cc(C3CC3)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(CCCC)C1=O)C)C(O)C1[NH2+]CC(O)C1 +Clc1ccc(nc1)C(=O)Nc1cc(C2(N=C(N)C3C(C2)C3)C)c(F)cc1 +O(C)c1cccnc1-c1cc2cc(CC(C(=O)NCCC(C)(C)C)C)c(nc2cc1)N +O(C)c1ccc(cc1C)C1(N=C(C)C(=N1)N)c1cc(ccc1)-c1cncnc1 +Fc1cc(ccc1)-c1cc2c(OC(CC23N=C(N)N(C)C3=O)(C)C)cc1 +O(C)c1ccc(cc1)[C@@]1([NH+]=C(N2C1=NCCC2)N)c1cc(ccc1)-c1cncnc1 +Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCC(NOC)CC1)c1cc(ccc1)C(C)(C)C +o1cccc1C(=O)Nc1cc(ccc1)C1(N=C(N)N(C)C1=O)C1CCCCC1 +O=C1N(C)C(=N[C@@]1(c1cc(ccc1)-c1cccnc1)c1cc(ncc1)C)N +Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCCCC1)c1cc(ccc1)C(C)=C +Fc1ccc(cc1OCCCCF)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 +O=C1N(C)C(=NC1(c1cc(ccc1)-c1cncnc1)c1cn(nc1)C)N +FC1(F)CN2C(=NC1)C(N=C2N)(c1cc(ccc1)-c1cncnc1)c1ccc(OC)cc1 +S1(=O)(=O)CC(Cc2cc(OCCOC)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 diff --git a/Dataset/bbbp.txt b/Dataset/bbbp.txt new file mode 100644 index 0000000000000000000000000000000000000000..af1c8abdfa31f8fa1fee079e0462bd55c326c669 --- /dev/null +++ b/Dataset/bbbp.txt @@ -0,0 +1,1567 @@ +[Cl].CC(C)NCC(O)COc1cccc2ccccc12 +C(=O)(OC(C)(C)C)CCCc1ccc(cc1)N(CCCl)CCCl +c12c3c(N4CCN(C)CC4)c(F)cc1c(c(C(O)=O)cn2C(C)CO3)=O +C1CCN(CC1)Cc1cccc(c1)OCCCNC(=O)C +Cc1onc(c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C(O)=O +CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(O)=O)CSc4nnnn4C)c5ccc(O)cc5)C(=O)C1=O +CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)c4c(O)cccc4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(/O)NCN5CCCC5)C1=O +Cn1c2CCC(Cn3ccnc3C)C(=O)c2c4ccccc14 +COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O +NC(N)=NC(=O)c1nc(Cl)c(N)nc1N +CC1=CN([C@H]2C[C@H](F)[C@@H](CO)O2)C(=O)NC1=O +C(Cl)Cl +C1N(C(CC2CCCCC12)C(NC(C)(C)C)=O)CC(C(Cc1ccccc1)NC(C(NC(c1nc2c(cccc2)cc1)=O)CC(N)=O)=O)O +CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c2ccccc2 +CCN1N=NN(CCN2CCC(CC2)(COC)N(C(=O)CC)c3ccccc3)C1=O +CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 +CN1C2CCC1CC(C2)OC(=O)[C@H](CO)c3ccccc3 +COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)[S](=O)(=O)NC(=O)NC3CCCCC3 +Nc1nnc(c(N)n1)c2cccc(Cl)c2Cl +CCCC(C)C +C[C@H](N)Cc1ccccc1 +CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12 +CCC(=O)N(c1ccccc1)C2(CCN(CCc3sccc3)CC2)COC +CN(C)C(=O)Cc1n2cc(C)ccc2nc1c3ccc(C)cc3 +CN1CCN(CC1)C2=C3C=CC=CC3=Nc4ccc(Cl)cc4N2 +FC(F)(F)c1c(Cl)nc(N2CCNCC2)cc1 +O.CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(O)=O)c4ccccc4)C(=O)C1=O +CCCC(C)C1(CC)C(=O)NC(=O)NC1=O +C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc4C(=O)C(=CN1c24)C(O)=O +c1ccc(C(NCCCOc2cc(CN3CCCCC3)ccc2)=O)cc1 +CC(C)(C)OC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CS3)C +CCC(=O)N(C1CCN(CC1)CCc2ccccc2)c3ccccc3 +CCOC(=O)c1cncn1C(C)c2ccccc2 +CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 +IC1=C(N([H])[H])C=CC(C2=NC3=CC=C(O[H])C=C3S2)=C1 +CN1[C@H]2CCC[C@@H]1CC(C2)NC(=O)c3nn(C)c4ccccc34 +C[S](=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl +c1ccc(cc1)c1csc(n1)N=C(N)N +CC(N)COc1c(C)cccc1C +CCC(=O)O[C@@](Cc1ccccc1)([C@H](C)CN(C)C)c2ccccc2 +ClC1=CC=C(C2=C1)SC3=C(N2CCCNC)C=CC=C3 +CN(C)Cc1ccc(c2cccc(NC3C([N+]([O-])=O)=CC=N3)c2)o1 +Cn1nnnc1SCC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@H](O)c4ccccc4)C3=O)C(O)=O +n(ccc1)c(c1)CCN(C)C +O=C1N(CCC1)CCCCN2CCN(CC2)c3cc(C(F)(F)F)ccn3 +COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 +c1(ccccc1)CC +c1ccc(cc1N)c1csc(n1)N=C(N)N +CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@H]7[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@H]89)C(=O)OC)C1 +c1(c(cc(NC(CCC)=O)cc1)C(C)=O)OCC(CNC(C)C)O +ClC1=CC=C(SC(C=CC=C2)=C2N3CCCN)C3=C1 +CN(C)Cc1ccc(CSCCNC2=C([N+]([O-])=O)C(Cc3ccccc3)=CN2)o1 +n(ccc1)c(c1)CCNC +O=N([O-])C1=C(CN=C1NCCSCc2ncccc2)Cc3ccccc3 +[Cl-].CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c3ccccc13.[H+] +c1(nc(NC(N)=[NH2])sc1)CSCCNC(=[NH]C#N)NC +CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)[C@H]7[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@H]89)C(=O)OC)C1 +CCC(NC(=O)c1c(c(nc2c1cccc2)c1ccccc1)C)c1ccccc1 +ClC1=CC=CC(OC2CCN(CCC3CCCN3S(C4=CC(N([H])C=C5)=C5C=C4)(=O)=O)CC2)=C1 +CN(C)Cc1ccnc(c2cccc(NC3C([N+]([O-])=O)=CC=N3)c2)c1 +CNCCCC12CCC(c3ccccc13)c4ccccc24 +N1(Cc2cc(OCCCNc3nccs3)ccc2)CCCCC1 +[Na+].CO\N=C(C(=O)N[C@@H]1[C@@H]2SCC(=C(N2C1=O)C([O-])=O)COC(C)=O)\c3csc(N)n3 +C1=CC=C2C(=C1)C3C(O3)C4=CC=CC=C4N2C(=O)N +C1CCCCC1 +Cc1csc(n1)N=C(N)N +CCCN(CCc1c2c(c(cc1)O)NC(=O)C2)CCC +Clc1cc2c(Oc3ccccc3C3CN(CC32)C)cc1 +CO/N=C(C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(O)=O)COC(N)=O)/c3occc3 +N1(Cc2cc(OCCCNc3oc4ccccc4n3)ccc2)CCCCC1 +OC12c3c(Oc4c(C)cccc4C2CN(CC1)C)cccc3 +[O-][N+](C1=CC=NC1NCCSCc2ccccn2)=O +c12c(nc([nH]1)NC(OC)=O)cc(SCCC)cc2 +Cc1ncc(n1CC(O)CCl)[N+]([O-])=O +CCCN(CCc1c2c(ccc1)NC(=O)C2)CCC +Clc1cc2c(Oc3ccccc3C3CNCC32)cc1 +CN(CCC=C1c2ccccc2CCc2ccccc12)C +CO/N=C(C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(O)=O)CSC3=NC(=O)C(=O)NN3C)/c4csc(N)n4 +N1(Cc2cccc(OCCCNc3ccccn3)c2)CCCCC1 +OC12c3c(Oc4c(C)cccc4C2CNCC1)cccc3 +[O-][N+](C1=CC=NC1NCCSCc2ncccc2Br)=O 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+Cl.N=C(N)n1cccn1 +Cl.Cl.N=C(NCCCCCCNC(=N)NC(=N)Nc1ccc(Cl)cc1)NC(=N)Nc1ccc(Cl)cc1 +CCOC(=O)c1c(C)cc(O)c(C=O)c1O +CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(COC(C)=O)CSC12)c1csc(N)n1.[Na+] +O=C(NC(CO)C(O)c1ccc([N+](=O)[O-])cc1)C(Cl)Cl +COc1c(N2CCNC(C)C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 +Cc1nnc(SCC2=C(C(=O)[O-])N3C(=O)C(NC(=O)Cn4cnnn4)C3SC2)s1.[Na+] +O=C1C=C2C(=CCOC2O)O1 +CC(=O)OCC1=C(C(=O)[O-])N2C(=O)C(NC(=O)Cc3cccs3)C2SC1.[Na+] +CCC1OC(=O)C(C)C(OC2CC(C)(OC)C(O)C(C)O2)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(O)CC(C)CN(C)C(C)C(O)C1(C)O +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2SCC4)CC1 +CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(C[N+]3(C)CCCC3)CSC12)c1csc(N)n1.[Cl-] +Cc1oc(=O)oc1CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)c2n3C(C)S2)CC1 +CNC1C(O)C(OC2C(N)CC(N)C(OC3OC(C(C)O)C(O)C(O)C3N)C2O)OCC1(C)O +Cl.NC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2Cl)C1 +Cc1scc2c1N(C(=O)CN1CCN(C)CC1)c1ccccc1NC2=O.Cl +O=C([O-])C1=C(CSc2nnnn2CS(=O)(=O)[O-])CSC2C(NC(=O)C(O)c3ccccc3)C(=O)N12.[Na+].[Na+] +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC +CN(C)CCC=C1c2ccccc2COc2ccc(CC(=O)O)cc21.Cl +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(CCF)c3c2F)CC1 +CC1(C)SC2C(N3C(=O)C(c4ccccc4)NC3(C)C)C(=O)N2C1C(=O)[O-].[K+] +NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)CC1O +Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1Cl +CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=C(CSC(=O)c3ccco3)CSC12)c1csc(N)n1.Cl +CC1COc2c(N3CCN(C)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 +COC1(NC(=O)C2SC(=C(C(N)=O)C(=O)O)S2)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC21 +Cc1cn(C2CC(N=[N+]=[N-])C(CO)O2)c(=O)[nH]c1=O +CC(N)O.Cc1cc(CC(C)CC(C)(C)C)n(O)c(=O)c1 +CCN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +NCc1ccccc1CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3CC(=O)O)CSC12 +CC1CCc2cc(F)cc3c(=O)c(C(=O)O)cn1c23 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21.CS(=O)(=O)O +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +Cl.O=C(O)c1cn(-c2ccc(F)cc2)c2cc(N3CCNCC3)c(F)cc2c1=O +O=C(Cn1cnnn1)NC1C(=O)N2C(C(=O)O)=C(CSc3nncs3)CSC12 +O=C1OCCN1N=Cc1ccc([N+](=O)[O-])o1 +COC1(NC(=O)CSCC#N)C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC21.[Na+] +COc1c(N2CC3CCCNC3C2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12.Cl +CCN1CCN(C(=O)NC(C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nnnn4C)CSC23)c2ccc(O)cc2)C(=O)C1=O +Nc1c2ccccc2nc2ccccc12 +O=C1CN(N=Cc2ccc([N+](=O)[O-])o2)C(=O)N1 +CC1CCC2(C)C(C=O)=CCCC2C1(C)CC1OC(O)C(=O)C12CO2 +CS(=O)(=O)c1ccc(C(O)C(CF)NC(=O)C(Cl)Cl)cc1 +Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)C(NC(=O)C(O)c3ccccc3)C2SC1.[Na+] +Cc1cc(C(C)(C)CC(C)(C)C)ccc1OCCOCC[N+](C)(C)Cc1ccccc1.[Cl-] +CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(COC(N)=O)CSC12)c1ccco1.[Na+] +CCN1CCN(C(=O)NC(C(=O)NC2C(=O)N3C2SC(C)(C)C3C(=O)[O-])c2ccccc2)C(=O)C1=O.[Na+] +NCCC(O)C(=O)NC1CC(N)C(OC2OC(CN)C(O)C(O)C2O)C(O)C1OC1OC(CO)C(O)C(N)C1O.O +CC(NCCCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12.Cl +CCC1OC(OC(c2c[nH]cn2)C(NC(=O)c2nc(C(CC(N)=O)NCC(N)C(N)=O)nc(N)c2C)C(=O)NC(C)C(O)C(C)C(=O)NC(C(=O)NCCc2nc(-c3nc(C(=O)NCCCCNC(=N)N)cs3)cs2)C(C)O)C(OC2OC(CO)C(O)C(OC(N)=O)C2O)C(C)C1C.O=S(=O)(O)O.O=S(=O)(O)O +CC(C)(C)CC(C)(C)c1ccc(OCCOCC[N+](C)(C)Cc2ccccc2)cc1.[Cl-] +NC(=O)NN=Cc1ccc([N+](=O)[O-])o1 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c3c2OCN4C)CC1 +CCC(C)C1NC(=O)C(CCN)NC(=O)C(NC(=O)C(CCN)NC(=O)C(NC(=O)C(CCN)NC(=O)CCCCC(C)C)C(C)O)CCNC(=O)C(C(C)O)NC(=O)C(CCN)NC(=O)C(CCN)NC(=O)C(C(C)CC)NC1=O.O=S(=O)(O)O.O=S(=O)(O)O +O=[N+]([O-])C(Br)(CO)CO +CC1COc2c(C3(N)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23.CS(=O)(=O)O +CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccc(F)cc2)CC1.Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c21.Cl +O=C(O)c1cn(C2CC2)c2cc(N3CCNCC3)c(F)cc2c1=O +CNC1C(O)C(NC)C2OC3(O)C(=O)CC(C)OC3OC2C1O.Cl.Cl +CCn1cc(C(=O)[O-])c(=O)c2cc3c(cc21)OCO3.[K+] +COC1(NC(=O)C(C(=O)[O-])c2ccc(O)cc2)C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)COC21.[Na+].[Na+] +NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(N)C(O)C1O.O=S(=O)(O)O +CC1CCc2c(N3CCC(O)CC3)c(F)cc3c(=O)c(C(=O)O)cn1c23 +CC[Hg]Sc1ccccc1C(=O)[O-].[Na+] +Nc1nc(C(=CCC(=O)O)C(=O)NC2C(=O)N3C(C(=O)O)=CCSC23)cs1 +CC1CN(c2c(F)c(F)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC(C)N1 +COc1cc2c(cc1OC)C(=O)C(CC1CCN(Cc3ccccc3)CC1)C2.Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +NC(C(=O)NC1C(=O)N2C(C(=O)O)=C(Cl)CSC12)c1ccccc1 +CN(C)CCOC(c1ccccc1)c1ccccc1.Cn1c(=O)c2[nH]c(Cl)nc2n(C)c1=O +CON=C(C(=O)NC1C(=O)N2C(C(=O)OCOC(=O)C(C)(C)C)=C(C=Cc3scnc3C)CSC12)c1csc(N)n1 +Cl.O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ncccn2)CC1 +CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nc(=O)c([O-])nn3C)CSC12)c1csc(N)n1.O.O.O.[Na+].[Na+] +CC1CN(c2c(F)c(N)c3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC(C)N1 +COP(=S)(OC)Oc1cc(Cl)c(Cl)cc1Cl +CC1C(NC(=O)C(=NOC(C)(C)C(=O)O)c2csc(N)n2)C(=O)N1S(=O)(=O)O +CCC1OC(=O)C(C)C(=O)C(C)C(OC2OC(C)CC(N(C)C)C2O)C(C)(OC)CC(C)C(=O)C(C)C2N(CCCCn3cnc(-c4cccnc4)c3)C(=O)OC12C +COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(c5c(nc6cc(C)ccn65)c4c3C2=O)NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C +Nc1ncn(C2OC(CO)C(O)C2O)c(=O)n1 +C=CC1=C(C(=O)O)N2C(=O)C(NC(=O)C(=NO)c3csc(N)n3)C2SC1 +CCn1cc(C(=O)O)c(=O)c2cnc(N3CCNCC3)nc21 +COc1ccc(Cc2cnc(N)nc2N)cc1OC +COC12C(COC(N)=O)C3=C(C(=O)C(C)=C(N)C3=O)N1CC1NC12 +[O-][n+]1ccccc1S[Zn]Sc1cccc[n+]1[O-] +CC(C)(ON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(C[n+]3ccccc3)CSC12)c1csc(N)n1)C(=O)O +CCOC(=O)OC(C)OC(=O)C1N2C(=O)C(NC(=O)C(N)c3ccccc3)C2SC1(C)C.Cl +COc1ccc2c(c1OC)C(=O)OC2C1c2c(cc3c(c2OC)OCO3)CCN1C.Cl +O=C([O-])CCC(=O)OCC(NC(=O)C(Cl)Cl)C(O)c1ccc([N+](=O)[O-])cc1.[Na+] +CC(O)C1C(=O)N2C(C(=O)O)=C(SC3CNC(C(=O)N(C)C)C3)C(C)C12 +CN(C)C1C(O)=C(C(N)=O)C(=O)C2(O)C(O)=C3C(=O)c4c(O)cccc4C(C)(O)C3CC12.Cl +CCCCCCCCCCCCCCCC[N+](C)(C)C.[Br-] +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1F +CCC(C)C1NC(=O)C(CCNCS(=O)(=O)[O-])NC(=O)C(NC(=O)C(CCNCS(=O)(=O)[O-])NC(=O)C(NC(=O)C(CCNCS(=O)(=O)[O-])NC(=O)CCCCC(C)C)C(C)O)CCNC(=O)C(C(C)O)NC(=O)C(CCNCS(=O)(=O)[O-])NC(=O)C(CCNCS(=O)(=O)[O-])NC(=O)C(C(C)CC)NC1=O.[Na+].[Na+].[Na+].[Na+].[Na+] +Cc1cc(C2CCCCC2)n(O)c(=O)c1.NCCO +CCn1nc(C(=O)O)c(=O)c2cc3c(cc21)OCO3 +O=[N+]([O-])c1ccc(O)c2ncccc12 +CCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1.O.[Cl-] +C=C1c2cccc(O)c2C(=O)C2=C(O)C3(O)C(=O)C(C(N)=O)=C(O)C(N(C)C)C3C(O)C12.Cl +Oc1c(Cl)cc(Cl)c(Cl)c1Cc1c(O)c(Cl)cc(Cl)c1Cl +CC(=O)O[Hg]c1ccccc1 +CN(C)C1C(O)=C(C(N)=O)C(=O)C2(O)C(O)=C3C(=O)c4c(O)ccc(Cl)c4C(O)C3CC12.Cl +CC(=O)Oc1ccc(Cl)c2cccnc12 +CN(C)C1C(O)=C(C(N)=O)C(=O)C2(O)C(O)=C3C(=O)c4c(O)cccc4C(C)(O)C3C(O)C12.Cl +CN(C)C1C(O)=C(C(N)=O)C(=O)C2(O)C(O)=C3C(=O)c4c(O)ccc(Cl)c4C(C)(O)C3CC12.Cl +CC1c2cccc(O)c2C(=O)C2=C(O)C3(O)C(=O)C(C(N)=O)=C(O)C(N(C)C)C3C(O)C21.Cl +CN(C)c1ccc(O)c2c1CC1CC3C(N(C)C)C(O)=C(C(N)=O)C(=O)C3(O)C(O)=C1C2=O.Cl +CNC1C(OC2C(OC3C(O)C(O)C(NC(=N)N)C(O)C3NC(=N)N)OC(C)C2(O)CO)OC(CO)C(O)C1O.O=S(=O)(O)O +COC1(NC(=O)Cc2cccs2)C(=O)N2C(C(=O)[O-])=C(COC(N)=O)CSC21.[Na+] +CCCCCCCCCCCCCCCC[n+]1ccccc1.[Cl-] +COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(c(C=NN5CCN(C6CCCC6)CC5)c(O)c4c3C2=O)NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C +CCC=C(C(=O)NC1C(=O)N2C(C(=O)OCOC(=O)C(C)(C)C)=C(COC(N)=O)CSC12)c1csc(N)n1.Cl +COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(c(C=NN5CCN(C)CC5)c(O)c4c3C2=O)NC(=O)C(C)=CC=CC(C)C(O)C(C)C(O)C(C)C(OC(C)=O)C1C +Cc1ccc(S(=O)(=O)O)cc1.NC1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3-c2ccc(F)cc2F)C1.O +CCCCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1.[Cl-] +O=S(=O)(O)O.Oc1cccc2cccnc12 +Oc1c(Cl)cc(Cl)c2cccnc12 diff --git a/Dataset/functions.csv b/Dataset/functions.csv new file mode 100644 index 0000000000000000000000000000000000000000..6083018652154fe92e56e4909d0ed2e5428e23ae --- /dev/null +++ b/Dataset/functions.csv @@ -0,0 +1,1246 @@ +,Len,Functional grp name,SMARTS,Smiles,Validity +0,7,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +1,8,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O,Valid +2,15,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1,Valid +3,5,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O,Valid +4,8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1,Valid +5,4,Thioesters,[CX3](=[SX1])[SX2],SC=S,Valid +6,13,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl,Valid +7,5,Epoxides,[CX4]1[CX4][OX2]1,C1CO1,Valid +8,12,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +9,13,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC,Valid +10,11,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1,Valid +11,18,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +12,16,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH],Valid +13,18,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1,Valid +14,16,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1,Valid +15,16,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1,Valid +16,14,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH],Valid +17,4,Thiols,[#16X2H1],[SH],Valid +18,7,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH],Valid +19,7,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S,Valid +20,3,Nitroso (general),[NX2]=[OX1],N=O,Valid +21,3,Azo-type (general),[NX2]=[NX2],N=N,Valid +22,5,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O,Valid +23,5,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1,Valid +24,8,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1,Valid +25,4,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N,Valid +26,32,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1,Valid +27,32,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1,Valid +28,11,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O,Valid +29,6,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O,Valid +30,8,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +31,11,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH],Valid +32,7,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +33,5,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O,Valid +34,2,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN,Valid +35,5,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O,Valid +36,6,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC,Valid +37,18,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +38,8,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O,Valid +39,10,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O,Valid +40,11,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O,Valid +41,8,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +42,5,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O,Valid +43,5,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S,Valid +44,18,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +45,7,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl,Valid +46,5,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1,Valid +47,7,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O,Valid +48,10,Primary alkyl amines,[CH2][NH2],[CH2][NH2],Valid +49,18,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3],Valid +50,20,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1,Valid +51,22,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +52,13,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1,Valid +53,19,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21,Valid +54,7,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +55,7,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC,Valid +56,4,Thiocyanates,[SX2][CX2]#[NX1],N#CS,Valid +57,21,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O,Valid +58,12,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +59,6,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O,Valid +60,6,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C,Valid +61,6,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N,Valid +62,12,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C,Valid +63,7,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S,Valid +64,7,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S,Valid +65,2,Peroxides,[OX2][OX2],OO,Valid +66,2,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS,Valid +67,4,Nitroso,[#6][NX2]=[OX1],CN=O,Valid +68,4,N-Nitroso,[#7][NX2]=[OX1],NN=O,Valid +69,5,Azo,[#6][NX2]=[NX2][#6],CN=NC,Valid +70,5,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC,Valid +71,5,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C,Valid +72,6,Hydroxylamines,[OH1][NX3][#6],CN[OH],Valid +73,3,Aminals,N[CX4]N,NCN,Valid +74,12,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C,Valid +75,9,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C,Valid +76,9,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O,Valid +77,9,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O,Valid +78,9,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C,Valid +79,10,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O,Valid +80,6,Acrylonitriles,[NX1]#CC=C,C=CC#N,Valid +81,12,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O,Valid +82,14,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1,Valid +83,5,Ketenes,[CX3]=[CX2]=[OX1],C=C=O,Valid +84,5,Allenes,C=C=C,C=C=C,Valid +85,5,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1,Valid +86,5,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1,Valid +87,5,Aziridines,[CX4]1[NX3][CX4]1,C1CN1,Valid +88,6,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1,Valid +89,6,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1,Valid +90,6,Selen in chain,[Sev2X2],[SeH2],Valid +91,12,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O,Valid +92,12,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N,Valid +93,4,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O,Valid +94,7,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S,Valid +95,7,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S,Valid +96,7,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S,Valid +97,7,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S,Valid +98,11,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O,Valid +99,1,Positively charged N-heterocycles,[#7v4X3R],N,Valid +100,18,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH],Valid +101,20,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1,Valid +102,22,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1,Valid +103,25,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1,Valid +104,27,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1,Valid +105,18,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12,Valid +106,12,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl,Valid +107,12,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O,Valid +108,13,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC,Valid +109,13,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC,Valid +110,9,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O,Valid +111,6,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N,Valid +112,11,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C,Valid +113,10,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O,Valid +114,10,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C,Valid +115,12,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH],Valid +116,12,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C,Valid +117,9,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C,Valid +118,2,Iodine,II,II,Valid +119,8,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H],Valid +120,3,Sulfoxides,[Sv4X3](=[OX1]),O=S,Valid +121,2,Sulfenyl iodides,[SX2][IX1],SI,Valid +122,4,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS,Valid +123,8,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S,Valid +124,8,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS,Valid +125,7,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH],Valid +126,41,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1,Valid +127,5,Organotin compounds,[Sn][#6],C[Sn],Valid +128,8,β-Lactones,C1C(=O)OC1,O=C1CCO1,Valid +129,8,Thio-lactones,C1C(=O)SC1,O=C1CCS1,Valid +130,10,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC,Valid +131,26,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH],Valid +132,14,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1,Valid +133,11,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2],Valid +134,14,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1,Valid +135,11,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1,Valid +136,5,Sulfuranes,C1[SX2]C1,C1CS1,Valid +137,11,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1,Valid +138,12,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O,Valid +139,8,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O,Valid +140,16,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl,Valid +141,17,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C,Valid +142,18,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C,Valid +143,39,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH],Valid +144,19,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH],Valid +145,15,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1,Valid +146,30,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21,Valid +147,11,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O,Valid +148,24,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O,Valid +149,20,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1,Valid +150,7,Furans,c1ccc[oX2]1,c1ccoc1,Valid +151,7,Thiophenes,c1ccc[sX2]1,c1ccsc1,Valid +152,17,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O,Valid +153,10,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH],Valid +154,4,Thioles,[Sv2X2H1],[SH],Valid +155,8,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O,Valid +156,11,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH],Valid +157,1,Phosphorus,P,P,Valid +158,6,Selen,[Se],[SeH2],Valid +159,1,Bor,B,B,Valid +160,6,Silicium,[Si],[SiH4],Valid +161,3,Thione,[CX3]=[SX1!R],C=S,Valid +162,9,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH],Valid +163,7,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S,Valid +164,25,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2],Valid +165,12,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O,Valid +166,16,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1,Valid +167,16,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1,Valid +168,16,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1,Valid +169,16,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1,Valid +170,17,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1,Valid +171,6,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O,Valid +172,6,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N,Valid +173,16,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O,Valid +174,10,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N,Valid +175,12,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S,Valid +176,34,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12,Valid +177,40,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O,Valid +178,16,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH],Valid +179,2,N-N Single bound not in a ring,[N!R][N!R],NN,Valid +180,11,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC,Valid +181,10,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O,Valid +182,12,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1,Valid +183,15,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O,Valid +184,18,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3,Valid +185,18,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3,Valid +186,21,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1,Valid +187,18,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23,Valid +188,6,Cyano carbonyl compounds ,N#CC(=O),N#CC=O,Valid +189,5,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N,Valid +190,6,Benzyl ammoniums,cC[NX4+],cC[N+],Valid +191,8,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O,Valid +192,9,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N,Valid +193,7,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O,Valid +194,3,Singel acyclic N-N bonds,[#7]!@-N,N~N,Valid +195,11,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N,Valid +196,7,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O,Valid +197,2,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS,Valid +198,8,Phosphonates,[#6]P(=O)O[#6],COP(C)=O,Valid +199,16,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +200,14,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O,Valid +201,4,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS,Valid +202,13,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O,Valid +203,11,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F,Valid +204,4,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O,Valid +205,20,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1,Valid +206,15,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1,Valid +207,3,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC,Valid +208,4,Phosphocyanates,PC#N,N#CP,Valid +209,8,α-Hydroxy nitriles,N#CC[OH],N#CC[OH],Valid +210,6,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O,Valid +211,2,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO,Valid +212,11,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N,Valid +213,3,Nitroso compounds,[NX2]=O,N=O,Valid +214,19,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F,Valid +215,22,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +216,17,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1,Valid +217,1,Phosphorus derivatives,[P!v5],P,Valid +218,12,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C,Valid +219,22,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1,Valid +220,18,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1,Valid +221,17,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1,Valid +222,17,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1,Valid +223,7,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O,Valid +224,15,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O,Valid +225,14,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1,Valid +226,6,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC,Valid +227,16,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH],Valid +228,18,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1,Valid +229,20,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21,Valid +230,14,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH],Valid +231,17,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1,Valid +232,15,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21,Valid +233,6,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c,Valid +234,11,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N,Valid +235,6,Phosphorus cations,[#15+],[PH4+],Valid +236,10,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O,Valid +237,3,Double P=O bonds,[#15]=O,O=P,Valid +238,5,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH],Valid +239,7,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +240,3,Nitrosos,[NX2]=[OX1],N=O,Valid +241,10,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F,Valid +242,7,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S,Valid +243,5,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH],Valid +244,12,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH],Valid +245,12,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH],Valid +246,5,Phenols,c[OH1],c[OH],Valid +247,3,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC,Valid +248,3,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc,Valid +249,3,Diarylethers,c[OX2&!$([OX2r3])]c,cOc,Valid +250,6,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid +251,6,Primary aromatic amines,[NX3H2]c,c[NH2],Valid +252,6,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C,Valid +253,6,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C,Valid +254,6,Secondary aromatic amines,[NX3H1](c)c,c[NH]c,Valid +255,6,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C,Valid +256,5,Organolithium compounds,[Li][#6],[Li]C,Valid +257,5,Organomagnesium compounds,[Mg][#6],C[Mg],Valid +258,7,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O,Valid +259,10,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O,Valid +260,7,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O,Valid +261,11,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH],Valid +262,9,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC,Valid +263,10,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH],Valid +264,13,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC,Valid +265,12,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O,Valid +266,11,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O,Valid +267,8,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O,Valid +268,7,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O,Valid +269,6,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH],Valid +270,4,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC,Valid +271,7,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C,Valid +272,5,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH],Valid +273,5,Thiophenols,c[Sv2H1],c[SH],Valid +274,13,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH],Valid +275,13,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH],Valid +276,6,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C,Valid +277,10,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O,Valid +278,12,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH],Valid +279,6,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C,Valid +280,7,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C,Valid +281,7,Alkynyl alcohols,[CX2]#[CX2][OH1],C#C[OH],Valid +282,7,Alkynyl thiols,[CX2]#[CX2][SH1],C#C[SH],Valid +283,21,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O,NC(COP(O)(O)=O)C(O)=O,Valid +284,24,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O,CC(OP(O)(O)=O)C(N)C(O)=O,Valid +285,31,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,Valid +286,10,sulphonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +287,14,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S,O=C(S)C(F)(F)F,Valid +288,5,hydroxamate_warhead,C([N;H1]([O;D1]))=O,ONC=O,Valid +289,12,thiol_warhead,NC(C[S;D1])C(O)=O,NC(CS)C(O)=O,Valid +290,6,acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +291,25,pentafluorophenylester,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +292,10,acyl_imidazole,"[C;!$(C-N)](=O)n1[c;H1,$([#6]([*;!R]))]n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1ccnc1,Valid +293,16,ortho_hydroiminoquinone,c1c([N;D1])c([N;D1])c[cH1][cH1]1,Nc1c[cH][cH]cc1N,Valid +294,3,phosphorus_phosphorus_bond,P~P,P~P,Valid +295,10,acyl_pyrazole,"[C;!$(C-N)](=O)n1n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1cccn1,Valid +296,12,acyl_123_triazole,"[#7;R1]1=,:[#7;R1]-,:[#7;R1](-C(=O))-,:[#6]=,:[#6]1",O=CN1C=CN=N1,Valid +297,7,alpha_dicarbonyl,C(=O)!@C(=O),O=C~C=O,Valid +298,14,trifluoroacetate_ester,C(F)(F)(F)C(=O)O,OC(=O)C(F)(F)F,Valid +299,2,sulf_D2_nitrogen,[S;D2](-[N;!$(N(=C));!$(N(-S(=O)(=O)));!$(N(-C(=O)))]),NS,Valid +300,18,triflate,OS(=O)(=O)(C(F)(F)(F)),OS(=O)(=O)C(F)(F)F,Valid +301,15,rhodanine,C(=C)1SC(=S)NC(=O)1,C=C1SC(=S)NC1=O,Valid +302,5,NO_phosphonate,P(=O)ON,NOP=O,Valid +303,3,azo_filter3,[N;!R]-[N;!R]-[N;!R],NNN,Valid +304,30,disulfonyliminoquinone,S(=O)(=O)N=C1C=CC(=NS(=O)(=O))C=C1,O=S(=O)N=C1C=CC(=NS(=O)=O)C=C1,Valid +305,28,perchloro_cp,C1(Cl)(Cl)C(Cl)C(Cl)=C(Cl)C1(Cl),ClC1C(Cl)=C(Cl)C(Cl)C1(Cl)Cl,Valid +306,20,meldrums_acid_deriv,O=C1OC(C)(C)OC(C1)=O,CC1(C)OC(=O)CC(=O)O1,Valid +307,2,sulf_D2_oxygen_D2,[S;D2][O;D2],OS,Valid +308,3,azo_filter2,[N;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!r3;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!$(N-S(=O)(=O));!$(N-C=O)],NNN,Valid +309,2,hydrazine,[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))]-[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))],NN,Valid +310,10,isonitrile,[N+]#[C-],[C-]#[NH+],Valid +311,14,gte_3_COOH,C(=O)[O;D1].C(=O)[O;D1].C(=O)[O;D1],OC=O.OC=O.OC=O,Valid +312,3,phosphorus_sulfur_bond,P~S,P~S,Valid +313,9,polyene,C=[C;!R][C;!R]=[C;!R][C;!R]=[C;!R],C=CC=CC=C,Valid +314,4,azo_amino,[N]=[N;!R]-[N],N=NN,Valid +315,7,nitrone,[C;!R]=[N+][O;D1],C=[N+]O,Valid +316,1,sulfonium,[S+;X3;$(S-C);!$(S-[O;D1])],S,Valid +317,3,polysulfide,[S;D2]-[S;D2]-[S;D2],SSS,Valid +318,6,acrylate,[CH2]=[C;!$(C-N);!$(C-O)]C(=O),C=CC=O,Valid +319,15,four_nitriles,C#N.C#N.C#N.C#N,C#N.C#N.C#N.C#N,Valid +320,3,phosphorane,C=P,C=P,Valid +321,20,gte_7_aliphatic_OH,C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1],CO.CO.CO.CO.CO.CO.CO,Valid +322,9,gte_2_free_phos,P([O;D1])=O.P([O;D1])=O,OP=O.OP=O,Valid +323,22,benzidine_like,c([N;!+])1ccc(c2ccc([N;!+])cc2)cc1,Nc1ccc(c2ccc(N)cc2)cc1,Valid +324,9,hydrazothiourea,[N;!R]=NC(=S)N,NC(=S)N=N,Valid +325,4,nitrosamine,N-[N;X2](=O),NN=O,Valid +326,10,gte_10_carbon_sb_chain,[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R],CCCCCCCCCC,Valid +327,10,betalactam,C1(=O)~[#6]~[#6]N1,O=C1NC~C~1,Valid +328,3,peroxide,[#8]~[#8],O~O,Valid +329,18,paraquat_like,[#6]1[#6][#6]([#6]2[#6][#6][#7;+][#6][#6]2)[#6][#6][#7;+]1,C1CC(C2CCNCC2)CCN1,Valid +330,5,azo_aryl,c[N;!R;!+]=[N;!R;!+]-c,cN=Nc,Valid +331,2,disulfide_acyclic,[S;!R;X2]-[S;!R;X2],SS,Valid +332,5,gte_3_iodine,[#53].[#53].[#53],I.I.I,Valid +333,17,porphyrin,"[#6;r16,r17,r18]~[#6]1~[#6]~[#6]~[#6](~[#6])~[#7]1",C~C1N~C(~C)~C~C~1,Valid +334,7,thio_xanthate,[S;!R]-[C;!R](=[S;!R])(-[S;!R]),S=C(S)S,Valid +335,13,double_trouble_warhead,NC(C[S;D1])C([N;H1]([O;D1]))=O,NC(CS)C(=O)NO,Valid +336,13,Hzone_phenol_A,c1ccc(c(c1)[#8!H0])[#6]=[#7][#7],NN=Cc1ccccc1O,Valid +337,3,Azo_A,[N!R]=N,N=N,Valid +338,14,Mannich_A,N[CX4]c1c([OH1])cccc1,NCc1ccccc1[OH],Valid +339,15,Ene_rhod_A,N1C(=S)SC(=C)C1=O,C=C1SC(=S)NC1=O,Valid +340,18,Hzone_phenol_B,c1(ccc(cc1)C=N[#7])[OH1],NN=Cc1ccc([OH])cc1,Valid +341,20,Imine_one_isatin,[OX1]=C2C(=;!@N[#7])c3c(cccc3)N2,NN=C1C(=O)Nc2ccccc21,Valid +342,18,Anil_di_alk_B,c1c(ccc(c1)[#6]=[#6])[#7]([CX4])[CX4],CN(C)c1ccc(C=C)cc1,Valid +343,16,Catechol_A,c1ccc(c(c1)[OH1])[OH1],[OH]c1ccccc1[OH],Valid +344,21,Ene_five_one_A,c2ccc1C(=[OX1])C(=C)C(=[OX1])c1c2,C=C1C(=O)c2ccccc2C1=O,Valid +345,12,Ene_five_het_B,C1(=C)C(N=CS1)=O,C=C1SC=NC1=O,Valid +346,15,Ene_five_het_D,C1(=C)C(=[OX1])NNC1=[OX1],C=C1C(=O)NNC1=O,Valid +347,27,Ene_five_het_F,c1(ccccc1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)S2,O=C1C(=Cc2ccccc2)Sc2ccccc21,Valid +348,20,Ene_one_ester,[#6][#6](=[#8])[#6!H0]=[#6]([#7!H0][#6])[#6](=[#8])[#8][#6],CNC(=CC(C)=O)C(=O)OC,Valid +349,18,Ene_one_D,c([OH1])c-C(=[OX1])[C!H0]=C([#6])[#6],CC(C)=CC(=O)cc[OH],Valid +350,19,Ene_cyano_A,[#6](C#[#7])(C#[#7])=Cc1ccccc1,N#CC(=Cc1ccccc1)C#N,Valid +351,21,Hzone_pyrrol,n1(C)[cH1][cH1][cH1]c1C=NN,Cn1[cH][cH][cH]c1C=NN,Valid +352,45,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2,C=NNC(=O)c1[cH]c2[cH][cH][cH][cH]c2[cH]c1[OH],Valid +353,19,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1,O=C1CC(=O)c2ccccc21,Valid +354,22,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1],N#CC=C([NH2])C(C#N)C#N,Valid +355,20,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1,N#CC(C#N)=NNc1ccccc1,Valid +356,20,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9,C1C=CC2C1CNc1ccccc12,Valid +357,21,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7],Nc1c2ccccc2nc2ccccc12,Valid +358,13,Thiophene_hydroxy,"[#16]1-,:[#6]=,:[#6]-,:[#6](=,:[#6]1)[OH1]",[OH]C1=CSC=C1,Valid +359,25,Sulfonamide_B,c1c(ccc(c1)[NH]S(=[OX1])=[OX1])[OH1],O=S(=O)[NH]c1ccc([OH])cc1,Valid +360,7,Thio_ketone,"[#6]-,:[CX3](=[SX1])-,:[#6]",CC(C)=S,Valid +361,13,Rhod_sat_A,"[#7]1-,:[#6](=[#16])-,:[#16]-,:[#6X4]-,:[#6]1=[#8]",O=C1CSC(=S)N1,Valid +362,20,Imine_one_sixes,C1(C(=[OX1])NC(=[OX1])NC1(=[OX1]))=N,N=C1C(=O)NC(=O)NC1=O,Valid +363,22,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1,Valid +364,21,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1,Valid +365,21,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH],Valid +366,34,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +367,46,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH],Valid +368,31,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH],Valid +369,31,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1,Valid +370,51,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1,Valid +371,25,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH],Valid +372,36,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1,Valid +373,14,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1,Valid +374,27,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2,Valid +375,72,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1,Valid +376,39,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12,Valid +377,24,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC,Valid +378,27,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1,Valid +379,40,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1,Valid +380,32,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH],Valid +381,45,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12,Valid +382,38,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1,Valid +383,21,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2],Valid +384,39,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1,Valid +385,27,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12,Valid +386,31,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1,Valid +387,34,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12,Valid +388,52,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1,Valid +389,25,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1,Valid +390,30,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1,Valid +391,18,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1,Valid +392,46,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1,Valid +393,18,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1,Valid +394,22,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1,Valid +395,34,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2,Valid +396,18,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1,Valid +397,46,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +398,39,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1,Valid +399,32,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1,Valid +400,34,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12,Valid +401,17,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1,Valid +402,29,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O,Valid +403,21,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12,Valid +404,29,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21,Valid +405,48,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1,Valid +406,48,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1,Valid +407,22,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1,Valid +408,38,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc,Valid +409,34,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1,Valid +410,45,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1,Valid +411,19,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3,Valid +412,33,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21,Valid +413,22,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21,Valid +414,28,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12,Valid +415,18,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1,Valid +416,14,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1,Valid +417,20,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc,Valid +418,13,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1,Valid +419,26,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1,Valid +420,42,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1,Valid +421,18,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1,Valid +422,41,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21,Valid +423,48,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12,Valid +424,52,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21,Valid +425,10,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1,Valid +426,22,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1,Valid +427,16,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2,Valid +428,19,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc,Valid +429,44,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1,Valid +430,24,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21,Valid +431,26,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2,Valid +432,29,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21,Valid +433,30,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc,Valid +434,33,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21,Valid +435,15,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN,Valid +436,15,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S,Valid +437,12,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N,Valid +438,65,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1,Valid +439,25,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1,Valid +440,12,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S,Valid +441,23,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S,Valid +442,24,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1,Valid +443,47,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1,Valid +444,16,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O,Valid +445,17,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S,Valid +446,15,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1,Valid +447,41,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O,Valid +448,19,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1,Valid +449,31,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N,Valid +450,28,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21,Valid +451,21,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N,Valid +452,39,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2],Valid +453,48,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1,Valid +454,19,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N,Valid +455,27,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N,Valid +456,24,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc,Valid +457,16,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O,Valid +458,14,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O,Valid +459,19,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O,Valid +460,22,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12,Valid +461,23,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc,Valid +462,25,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1,Valid +463,15,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C,Valid +464,15,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1,Valid +465,18,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1,Valid +466,29,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O,Valid +467,33,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1,Valid +468,24,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1,Valid +469,28,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1,Valid +470,10,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1,Valid +471,22,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1,Valid +472,26,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1,Valid +473,25,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1,Valid +474,18,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S,Valid +475,18,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12,Valid +476,44,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1,Valid +477,52,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1,Valid +478,19,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2,Valid +479,22,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1,Valid +480,11,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1,Valid +481,22,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N,Valid +482,20,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12,Valid +483,27,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C,Valid +484,30,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N,Valid +485,28,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1,Valid +486,32,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH],Valid +487,23,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc,Valid +488,33,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12,Valid +489,35,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1,Valid +490,13,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1,Valid +491,20,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O,Valid +492,10,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH],Valid +493,27,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O,Valid +494,20,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21,Valid +495,20,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1,Valid +496,50,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21,Valid +497,42,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21,Valid +498,33,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1,Valid +499,13,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O,Valid +500,22,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O,Valid +501,21,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1,Valid +502,30,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O,Valid +503,11,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C,Valid +504,20,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1,Valid +505,20,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1,Valid +506,16,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21,Valid +507,11,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C,Valid +508,17,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O,Valid +509,15,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH],Valid +510,22,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S,Valid +511,24,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1,Valid +512,34,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1,Valid +513,32,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21,Valid +514,36,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O,Valid +515,24,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1,Valid +516,15,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1,Valid +517,29,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2],Valid +518,40,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1,Valid +519,26,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1,Valid +520,15,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc,Valid +521,25,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1,Valid +522,54,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1,Valid +523,34,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1,Valid +524,22,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc,Valid +525,12,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1,Valid +526,24,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1,Valid +527,24,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O,Valid +528,26,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1,Valid +529,18,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1,Valid +530,46,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1,Valid +531,26,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1,Valid +532,26,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3,Valid +533,25,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1,Valid +534,16,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N,Valid +535,28,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1,Valid +536,36,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O,Valid +537,38,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1,Valid +538,25,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1,Valid +539,38,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1,Valid +540,72,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2,Valid +541,56,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1,Valid +542,40,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1,Valid +543,20,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23,Valid +544,22,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2,Valid +545,35,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F,Valid +546,27,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2,Valid +547,35,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O,Valid +548,21,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1,Valid +549,38,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1,Valid +550,28,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1,Valid +551,32,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O,Valid +552,36,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1,Valid +553,29,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O,Valid +554,32,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O,Valid +555,61,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1,Valid +556,87,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH],Valid +557,27,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH],Valid +558,57,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1,Valid +559,59,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3],Valid +560,49,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1,Valid +561,49,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1,Valid +562,40,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH],Valid +563,23,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH],Valid +564,35,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1,Valid +565,39,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1,Valid +566,25,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1,Valid +567,81,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1,Valid +568,22,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1,Valid +569,31,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH],Valid +570,5,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1,Valid +571,5,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1,Valid +572,5,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1,Valid +573,6,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1,Valid +574,6,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1,Valid +575,6,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1,Valid +576,6,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1,Valid +577,5,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1,Valid +578,5,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1,Valid +579,5,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1,Valid +580,5,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1,Valid +581,6,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1,Valid +582,6,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1,Valid +583,6,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1,Valid +584,6,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1,Valid +585,5,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1,Valid +586,5,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1,Valid +587,5,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1,Valid +588,5,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1,Valid +589,5,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1,Valid +590,5,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1,Valid +591,5,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1,Valid +592,6,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1,Valid +593,6,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1,Valid +594,6,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1,Valid +595,6,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1,Valid +596,6,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1,Valid +597,6,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1,Valid +598,7,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1,Valid +599,7,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1,Valid +600,8,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1,Valid +601,7,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1,Valid +602,7,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1,Valid +603,6,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1,Valid +604,6,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1,Valid +605,6,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1,Valid +606,6,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1,Valid +607,6,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1,Valid +608,6,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1,Valid +609,7,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1,Valid +610,7,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1,Valid +611,7,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1,Valid +612,7,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1,Valid +613,7,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1,Valid +614,8,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1,Valid +615,8,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1,Valid +616,8,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1,Valid +617,8,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1,Valid +618,8,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1,Valid +619,8,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1,Valid +620,8,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1,Valid +621,7,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1,Valid +622,7,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1,Valid +623,7,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1,Valid +624,13,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1,Valid +625,13,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1,Valid +626,13,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1,Valid +627,7,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1,Valid +628,7,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1,Valid +629,7,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1,Valid +630,7,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1,Valid +631,7,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1,Valid +632,7,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1,Valid +633,8,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1,Valid +634,8,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1,Valid +635,8,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1,Valid +636,8,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1,Valid +637,8,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1,Valid +638,8,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1,Valid +639,8,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1,Valid +640,8,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1,Valid +641,8,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1,Valid +642,7,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1,Valid +643,7,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1,Valid +644,7,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1,Valid +645,7,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1,Valid +646,7,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1,Valid +647,7,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1,Valid +648,7,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1,Valid +649,7,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1,Valid +650,7,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1,Valid +651,7,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1,Valid +652,7,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1,Valid +653,7,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1,Valid +654,8,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1,Valid +655,8,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1,Valid +656,7,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1,Valid +657,7,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1,Valid +658,7,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1,Valid +659,7,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1,Valid +660,7,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1,Valid +661,7,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1,Valid +662,7,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1,Valid +663,7,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1,Valid +664,7,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1,Valid +665,7,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1,Valid +666,7,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1,Valid +667,7,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1,Valid +668,7,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1,Valid +669,7,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1,Valid +670,7,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1,Valid +671,7,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1,Valid +672,7,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1,Valid +673,7,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1,Valid +674,8,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1,Valid +675,8,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1,Valid +676,8,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1,Valid +677,9,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1,Valid +678,9,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1,Valid +679,8,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1,Valid +680,8,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1,Valid +681,8,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1,Valid +682,8,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1,Valid +683,8,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1,Valid +684,8,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1,Valid +685,8,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1,Valid +686,8,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1,Valid +687,8,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1,Valid +688,5,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C,Valid +689,5,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF,Valid +690,6,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl,Valid +691,6,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr,Valid +692,5,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI,Valid +693,4,Vinyl fluorides,F[CX3]=[CX3],C=CF,Valid +694,5,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl,Valid +695,5,Vinyl bromides,Br[CX3]=[CX3],C=CBr,Valid +696,4,Vinyl iodides,I[CX3]=[CX3],C=CI,Valid +697,4,Alkynyl fluorides,F[CX2]#[CX2],C#CF,Valid +698,5,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl,Valid +699,4,Alkynyl iodides,I[CX2]#[CX2],C#CI,Valid +700,5,Alkynyl bromides,Br[CX2]#[CX2],C#CBr,Valid +701,3,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC,Valid +702,3,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc,Valid +703,3,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc,Valid +704,10,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH],Valid +705,10,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH],Valid +706,5,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C,Valid +707,5,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C,Valid +708,7,Aldehyde,[CX3H1](=O)[#6],C[CH]=O,Valid +709,3,Formaldehyde,[CX3H2](=O),C=O,Valid +710,7,Ketone,[C][C](=O)[C],CC(C)=O,Valid +711,3,Nitrile,[C]#[N],C#N,Valid +712,27,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1,Valid +713,42,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1,Valid +714,19,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21,Valid +715,17,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21,Valid +716,14,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1,Valid +717,10,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1,Valid +718,14,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n,Valid +719,21,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12,Valid +720,21,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1,Valid +721,16,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1,Valid +722,10,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn,Valid +723,17,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1,Valid +724,18,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1,Valid +725,18,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12,Valid +726,18,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12,Valid +727,23,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12,Valid +728,26,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1,Valid +729,18,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1,Valid +730,18,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1,Valid +731,26,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1,Valid +732,18,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1,Valid +733,25,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1,Valid +734,21,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1,Valid +735,21,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12,Valid +736,18,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12,Valid +737,16,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH],Valid +738,16,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S,Valid +739,16,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH],Valid +740,16,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH],Valid +741,16,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S,Valid +742,22,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C,Valid +743,16,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH],Valid +744,22,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C,Valid +745,23,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S,Valid +746,19,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S,Valid +747,21,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH],Valid +748,22,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH],Valid +749,14,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH],Valid +750,11,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH],Valid +751,19,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1,Valid +752,16,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1,Valid +753,24,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1,Valid +754,21,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1,Valid +755,20,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1,Valid +756,11,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1,Valid +757,27,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21,Valid +758,30,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1,Valid +759,22,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12,Valid +760,16,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH],Valid +761,18,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH],Valid +762,22,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH],Valid +763,22,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH],Valid +764,28,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH],Valid +765,27,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH],Valid +766,25,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1,Valid +767,25,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1,Valid +768,29,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1,Valid +769,25,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1,Valid +770,13,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O,Valid +771,4,Pt,[Pt],[Pt],Valid +772,7,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +773,9,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O,Valid +774,34,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +775,28,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1,Valid +776,51,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1,Valid +777,46,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +778,33,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1,Valid +779,36,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21,Valid +780,11,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1,Valid +781,32,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12,Valid +782,35,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1,Valid +783,18,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH],Valid +784,21,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1,Valid +785,32,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1,Valid +786,19,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12,Valid +787,1,Radical,[#16;X3v3+0],S,Valid +788,4,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +789,9,6 - Methanol,[CX4H3][OX2H1],[CH3][OH],Valid +790,1,7 - Water,[OX2H2],O,Valid +791,7,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O,Valid +792,8,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +793,13,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +794,5,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S,Valid +795,15,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +796,18,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +797,1,32 - Iodo compounds,[I],I,Valid +798,2,33 - Bromo compounds,[Br!$([Br][cR])],Br,Valid +799,15,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +800,9,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +801,5,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl,Valid +802,8,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +803,26,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +804,27,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +805,7,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +806,6,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C,Valid +807,9,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH],Valid +808,3,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C,Valid +809,6,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C,Valid +810,3,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C,Valid +811,5,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c,Valid +812,4,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +813,9,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH],Valid +814,1,17 - H2O (7 - Water),[OX2H2],O,Valid +815,11,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O,Valid +816,11,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O,Valid +817,7,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O,Valid +818,12,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O,Valid +819,12,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O,Valid +820,8,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +821,7,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3],Valid +822,7,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2],Valid +823,10,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2],Valid +824,10,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2],Valid +825,9,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2],Valid +826,10,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3],Valid +827,10,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2],Valid +828,9,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH],Valid +829,10,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3],Valid +830,10,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2],Valid +831,23,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1,Valid +832,8,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N,Valid +833,8,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N,Valid +834,7,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH],Valid +835,10,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH],Valid +836,7,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl,Valid +837,9,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl,Valid +838,12,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl,Valid +839,13,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +840,5,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S,Valid +841,9,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH],Valid +842,9,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH],Valid +843,15,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +844,18,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +845,1,64 - I (32 - Iodo compounds),[I],I,Valid +846,2,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br,Valid +847,3,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C,Valid +848,3,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C,Valid +849,15,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +850,9,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +851,5,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl,Valid +852,19,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O,Valid +853,19,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O,Valid +854,8,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +855,6,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3],Valid +856,7,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2],Valid +857,6,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH],Valid +858,5,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si],Valid +859,26,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +860,12,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl,Valid +861,11,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl,Valid +862,10,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl,Valid +863,10,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl,Valid +864,11,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl,Valid +865,8,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O,Valid +866,12,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O,Valid +867,12,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O,Valid +868,16,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O,Valid +869,16,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O,Valid +870,16,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O,Valid +871,15,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH],Valid +872,27,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +873,21,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1,Valid +874,19,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O,Valid +875,18,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O,Valid +876,13,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1,Valid +877,12,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1,Valid +878,9,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1,Valid +879,11,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1,Valid +880,8,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1,Valid +881,5,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1,Valid +882,7,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +883,10,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O,Valid +884,11,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C,Valid +885,35,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1,Valid +886,11,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1,Valid +887,18,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1,Valid +888,14,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O,Valid +889,7,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O,Valid +890,2,R7 - Peroxides,OO,OO,Valid +891,25,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +892,21,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1,Valid +893,7,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O,Valid +894,18,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +895,7,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S,Valid +896,10,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +897,12,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-],Valid +898,5,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O,Valid +899,3,R19 - Phosphoranes,C=P,C=P,Valid +900,8,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +901,3,R21 - Nitroso,[N&D2](=O),N=O,Valid +902,5,R23 - Carbodiumide,N=C=N,N=C=N,Valid +903,10,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +904,13,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +905,8,R26 - Cyanohydrins,N#CC[OH],N#CC[OH],Valid +906,6,R27 - Acyl cyanides,N#CC(=O),N#CC=O,Valid +907,10,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O,Valid +908,16,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +909,6,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N,Valid +910,7,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +911,7,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC,Valid +912,7,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +913,2,I4 - Disulphides,SS,SS,Valid +914,4,I5 - Thiols,[SH],[SH],Valid +915,17,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +916,18,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +917,9,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +918,4,I10 - Thiocyanate,SC#N,N#CS,Valid +919,6,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+],Valid +920,9,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N,Valid +921,8,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1,Valid +922,19,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +923,8,I16 - Betalactams,N1CCC1=O,O=C1CCN1,Valid +924,16,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1,Valid +925,12,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +926,25,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +927,15,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +928,14,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +929,17,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +930,55,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1,Valid +931,14,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +932,13,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1,Valid +933,13,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1,Valid +934,20,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1,Valid +935,17,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O,Valid +936,12,A8,[nH1]1ncoc1=O,O=c1[nH]nco1,Valid +937,13,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1,Valid +938,15,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1,Valid +939,16,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1,Valid +940,13,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1,Valid +941,12,A13,[nH1]1occc1=O,O=c1cco[nH]1,Valid +942,11,A14,[OH1]c1oncc1,[OH]c1ccno1,Valid +943,12,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1,Valid +944,7,A16 - tetrazole,[nH1]nnn,nnn[nH],Valid +945,7,A17,[nH1](n)nn,nn[nH]n,Valid +946,16,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1,Valid +947,16,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1,Valid +948,18,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1,Valid +949,18,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1,Valid +950,16,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1,Valid +951,16,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1,Valid +952,16,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1,Valid +953,26,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21,Valid +954,26,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21,Valid +955,22,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21,Valid +956,16,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH],Valid +957,13,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1,Valid +958,8,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH],Valid +959,21,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F,Valid +960,12,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O,Valid +961,6,B1 - primary amine,[NH2][CX4],C[NH2],Valid +962,6,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C,Valid +963,6,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C,Valid +964,8,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1,Valid +965,7,E4EXC,C(=O)[OH1],O=C[OH],Valid +966,7,E5EXC,C(=O)[SH1],O=C[SH],Valid +967,5,E9EXC,P[OH1],[OH]P,Valid +968,9,E11,c(=O)(~c)~c,c~c(~c)=O,Valid +969,7,E13 - imides,C(=O)-N-C=O,O=CNC=O,Valid +970,6,N1 - pimary amines,[NX3H2][CX4],C[NH2],Valid +971,6,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C,Valid +972,7,N7EXC,[OH1]C=C,C=C[OH],Valid +973,4,Acyclic C=C-O,C=[C!r]O,C=CO,Valid +974,6,Acyl cyanide,N#CC(=O),N#CC=O,Valid +975,9,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O,Valid +976,13,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1,Valid +977,33,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1,Valid +978,11,Azido group,N=[N+]=[N-],[N-]=[N+]=N,Valid +979,3,Azo group,N=N,N=N,Valid +980,38,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1,Valid +981,14,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +982,6,Conjugated nitrile group,C=[C!r]C#N,C=CC#N,Valid +983,16,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1,Valid +984,9,Cyanamide,N[CH2]C#N,N[CH2]C#N,Valid +985,8,Cyanohydrins,N#CC[OH],N#CC[OH],Valid +986,9,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1,Valid +987,9,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1,Valid +988,10,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1,Valid +989,10,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1,Valid +990,3,Diazo group,[N!R]=[N!R],N=N,Valid +991,2,Disulphide,SS,SS,Valid +992,2,Enamine,[CX3R0][NX3R0],CN,Valid +993,7,Ester of HOBT,C(=O)Onnn,nnnOC=O,Valid +994,8,Four member lactones,C1(=O)OCC1,O=C1CCO1,Valid +995,13,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1,Valid +996,8,Hydroxamic acid,C(=O)N[OH],O=CN[OH],Valid +997,3,Imine,C=[N!R],C=N,Valid +998,5,Ketene,C=C=O,C=C=O,Valid +999,10,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1,Valid +1000,11,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O,Valid +1001,14,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1,Valid +1002,5,N-hydroxylpyridine,n[OH],n[OH],Valid +1003,4,N-nitroso,[#7]-N=O,NN=O,Valid +1004,10,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F,Valid +1005,2,Peroxide,OO,OO,Valid +1006,15,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1,Valid +1007,15,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1,Valid +1008,1,Phosphor,P,P,Valid +1009,6,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C,Valid +1010,25,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1011,21,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1,Valid +1012,10,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1013,2,Sulfur oxygen single bond,[SX2]O,OS,Valid +1014,14,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-],Valid +1015,2,Sulphur nitrogen single bond,[SX2H0][N],NS,Valid +1016,15,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1,Valid +1017,15,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1,Valid +1018,5,Thiol (1),[S-],[SH-],Valid +1019,4,Thiol (2),[SH],[SH],Valid +1020,18,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +1021,3,Triple bond,C#C,C#C,Valid +1022,5,Deuterium,[2H],[2HH],Valid +1023,7,C13,[13#6],[13CH4],Valid +1024,10,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1,Valid +1025,23,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O,Valid +1026,2,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN,Valid +1027,3,Acyclic N-C-N,N-!@[CX4]-!@N,NCN,Valid +1028,6,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O,Valid +1029,27,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O,Valid +1030,20,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1,Valid +1031,7,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O,Valid +1032,9,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N,Valid +1033,7,26,N-C(=S)-N,NC(N)=S,Valid +1034,4,Thio cyanates,S-C#N,N#CS,Valid +1035,11,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O,Valid +1036,12,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2],Valid +1037,30,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2],Valid +1038,3,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N,Valid +1039,2,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO,Valid +1040,2,42,S-S,SS,Valid +1041,3,43,O~O,O~O,Valid +1042,18,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3,Valid +1043,7,Too many cyano groups (>1),C#N.C#N,C#N.C#N,Valid +1044,15,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH],Valid +1045,12,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O,Valid +1046,4,Chlorates,Cl~O,O~Cl,Valid +1047,5,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O,Valid +1048,6,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C,Valid +1049,2,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN,Valid +1050,8,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH],Valid +1051,14,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O,Valid +1052,50,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3],Valid +1053,2,Filter35_PP_bond,P-P,PP,Valid +1054,3,Filter36_SS_double_bond,S=S,S=S,Valid +1055,8,Filter37_silicate,[Si]~O,O~[SiH4],Valid +1056,6,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O,Valid +1057,6,Filter51_PN3,N[PX3](N)N,NP(N)N,Valid +1058,16,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +1059,2,Filter56_SS_bond,S-S,SS,Valid +1060,15,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1,Valid +1061,15,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1,Valid +1062,3,Filter59_phoshorous_ylide,C=P,C=P,Valid +1063,3,Filter60_Acyclic_N-S,N!@[SX2],N~S,Valid +1064,24,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F,Valid +1065,14,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH],Valid +1066,7,Filter73_thio_ketone,CC(=S)C,CC(C)=S,Valid +1067,7,Filter76_S_ester,CC(=S)O,CC(O)=S,Valid +1068,20,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1,Valid +1069,4,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N,Valid +1070,3,Filter90_N_double_bond_S,N=!@S,N=S,Valid +1071,12,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O,Valid +1072,7,Anhydride,C(=O)OC(=O),O=COC=O,Valid +1073,26,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1,Valid +1074,7,HOBT ester,C(=O)Onnn,nnnOC=O,Valid +1075,12,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-],Valid +1076,6,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N,Valid +1077,8,Cyanohydrin,N#CC[OH],N#CC[OH],Valid +1078,8,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +1079,13,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +1080,6,Benzylic quaternary nitrogen,cC[N+],cC[N+],Valid +1081,3,Phosphorane,C=P,C=P,Valid +1082,7,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S,Valid +1083,16,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +1084,4,Thiol,[SH],[SH],Valid +1085,20,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1,Valid +1086,18,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +1087,17,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1088,18,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1089,7,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1090,9,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +1091,13,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH],Valid +1092,8,Ester,[#6]-C(=O)O-[#6],COC(C)=O,Valid +1093,3,Imine 3,C=[NH],C=N,Valid +1094,7,Thioketone,CC(=S)C,CC(C)=S,Valid +1095,8,Thionoester,COC(=S)C,COC(C)=S,Valid +1096,7,Thioamide,CC(=S)N,CC(N)=S,Valid +1097,6,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC,Valid +1098,10,Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +1099,4,Thiocyanate,SC#N,N#CS,Valid +1100,21,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1,Valid +1101,6,Dye 2,OCccCO,OCccCO,Valid +1102,2,Disulfide,SS,SS,Valid +1103,11,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N,Valid +1104,6,Oxalyl,O=C-&!@C=O,O=CC=O,Valid +1105,15,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-],Valid +1106,19,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1107,10,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O,Valid +1108,18,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12,Valid +1109,26,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21,Valid +1110,28,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O,Valid +1111,8,Propiolactone,C1(=O)OCC1,O=C1CCO1,Valid +1112,8,b-Lactam,N1CCC1=O,O=C1CCN1,Valid +1113,14,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +1114,25,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1115,17,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +1116,14,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +1117,57,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1,Valid +1118,15,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +1119,28,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1,Valid +1120,17,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1121,18,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1122,7,Acid_anhydrides,C(=O)OC(=O),O=COC=O,Valid +1123,20,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1,Valid +1124,6,Acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +1125,19,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F,Valid +1126,12,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C,Valid +1127,28,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O,Valid +1128,4,Aminonitrile,NC#N,NC#N,Valid +1129,13,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-],Valid +1130,7,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1131,21,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1,Valid +1132,14,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +1133,14,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1,Valid +1134,17,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1,Valid +1135,20,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1,Valid +1136,7,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +1137,19,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1138,6,Diacetylene,C#CC#C,C#CC#C,Valid +1139,11,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-],Valid +1140,7,Diazonium_salt,[N+]#N,N#[NH+],Valid +1141,15,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O,Valid +1142,7,Dithiocarbamate,NC(=S)S,NC(S)=S,Valid +1143,10,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1,Valid +1144,10,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1,Valid +1145,3,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS,Valid +1146,6,Enyne,C=!@CC#C,C#CC=C,Valid +1147,7,Ester_of_HOBT,C(=O)Onnn,nnnOC=O,Valid +1148,30,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2,Valid +1149,8,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF,Valid +1150,10,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F,Valid +1151,8,Four_member_lactones,C1(=O)OCC1,O=C1CCO1,Valid +1152,3,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN,Valid +1153,7,Geminal_dinitriles,N#CCC#N,N#CCC#N,Valid +1154,14,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1,Valid +1155,7,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S,Valid +1156,4,Nitrosamine,N-[N;X2](=O),NN=O,Valid +1157,8,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-],Valid +1158,3,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN,Valid +1159,9,Orthoester,C(O)(O)[OH],OC(O)[OH],Valid +1160,20,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH],Valid +1161,13,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1,Valid +1162,3,PCP,PCP,PCP,Valid +1163,25,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +1164,26,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1165,13,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1,Valid +1166,12,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O,Valid +1167,10,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +1168,12,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +1169,11,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc,Valid +1170,8,Polyines,CC#CC#CC,CC#CC#CC,Valid +1171,20,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1,Valid +1172,22,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12,Valid +1173,26,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1174,11,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1,Valid +1175,3,S=N (not_ring),[S;R0]=[N;R0],N=S,Valid +1176,9,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O,Valid +1177,10,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1178,3,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S,Valid +1179,9,Tetraazinane,C1NNC=NN1,C1NNC=NN1,Valid +1180,14,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S,Valid +1181,15,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1,Valid +1182,29,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1,Valid +1183,32,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1,Valid +1184,17,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O,Valid +1185,11,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O,Valid +1186,14,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1,Valid +1187,3,Thiocarbonyl_group,C=S,C=S,Valid +1188,3,Enamine_like,C=[NH],C=N,Valid +1189,14,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F,Valid +1190,4,Triple_bond,[#6]C#[CH],CC#C,Valid +1191,15,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O,Valid +1192,12,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1,Valid +1193,17,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1,Valid +1194,8,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1,Valid +1195,9,Thiazolidinone,O=C1CSCN1,O=C1CSCN1,Valid +1196,14,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1,Valid +1197,12,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1,Valid +1198,15,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1,Valid +1199,3,Ethene,C=[CH2],C=C,Valid +1200,7,Cyclobutene,C1CC=C1,C1CC=C1,Valid +1201,1,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C,Valid +1202,17,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-],Valid +1203,21,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-],Valid +1204,4,Sulphur atom (1),[SX2H1],[SH],Valid +1205,1,Sulphur atom (6),[sX2r5],s,Valid +1206,1,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C,Valid +1207,1,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C,Valid +1208,1,Nitrogen atoms (7),[nr5H0],n,Valid +1209,27,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21,Valid +1210,16,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C,Valid +1211,25,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1,Valid +1212,24,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1,Valid +1213,31,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1,Valid +1214,25,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1,Valid +1215,24,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1,Valid +1216,27,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1,Valid +1217,27,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1,Valid +1218,20,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1,Valid +1219,19,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1,Valid +1220,19,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1,Valid +1221,23,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1,Valid +1222,22,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2,Valid +1223,22,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC,Valid +1224,21,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1,Valid +1225,16,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1,Valid +1226,27,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1227,32,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1228,34,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1,Valid +1229,20,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1,Valid +1230,20,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1,Valid +1231,16,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1,Valid +1232,22,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1,Valid +1233,22,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12,Valid +1234,21,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1,Valid +1235,14,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1,Valid +1236,17,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1,Valid +1237,17,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1,Valid +1238,32,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1,Valid +1239,20,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1,Valid +1240,12,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2,Valid +1241,11,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2,Valid +1242,19,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1,Valid +1243,15,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2,Valid +1244,6,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid diff --git a/Dataset/vocab.csv b/Dataset/vocab.csv new file mode 100644 index 0000000000000000000000000000000000000000..a8d112ae53e12daec50e4a32374afc22776e5794 --- /dev/null +++ b/Dataset/vocab.csv @@ -0,0 +1,2787 @@ +,Functional grp name,SMARTS,Smiles +0,Acid halides,"[F,Cl,Br][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +1,Acid azides,"[CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C=O +2,Sulphonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[Cl,Br]",*S(C)(=O)=O +3,Sulphonyl azides,"[Sv6X4](=[OX1])(=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",*S(=O)=O +4,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +5,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O +6,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1 +7,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O +8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1 +9,Thioesters,[CX3](=[SX1])[SX2],SC=S +10,Haloalkanes,"[CX4][Cl,Br,I]",*C +11,Dialkylsulfates/ sulfonates,"[$([#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6]),$([#6][Sv6X4](=[OX1])(=[OX1])[OX2][#6])]",* +12,N-Trihalomethyl imides,"[CX3](=[OX1])[NX3]([CX4]([Cl,Br,I])([Cl,Br,I])[Cl,Br,I])[CX3](=[OX1])",*C(*)(*)N(C=O)C=O +13,Quinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]",* +14,Hydroquinones and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1][cR1][cR1]([OX2][#1,CX4])[cR1][cR1]1",*Oc1ccc(O*)cc1 +15,Catechols and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1]([OX2][#1,CX4])[cR1][cR1][cR1][cR1]1",*Oc1ccccc1O* +16,"α, β-Unsaturated aldehydes, amides, esters and ketones","[$([CX3]([#6,$([NX3]([CX3]=[OX1])([#6])[#6]),$([OX2]([CX3]=[OX1])[#6]);!$([OH][CX3]=[OX1]);!$([O-][CX3]=[OX1])])(=[OX1])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX3H1](=[OX1])[CX3]([#6,#1])=[CX3])]",* +17,"Precursors of α, β-unsaturated aldehydes, amides, esters and ketones (1)","[$([CX4]([OX2])([OX2])([#6,#7,#8])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX4H1]([OX2])([OX2])[CX3]([#6,#1])=[CX3])]",* +18,"1,3-Diketones","[CX4,a!r0][CX3](=[OX1])[CH2][CX3](=[OX1])[CX4,a!r0]",*C(=O)[CH2]C(*)=O +19,Aldehydes,"[CX3]([H])(=[OX1])[#1,CX4,a!r0]",*C([H])=O +20,Ketones,"[CX4,a!r0][CX3](=[OX1])[CX4,a!r0]",*C(*)=O +21,Formaldehyde donors,"[$([NX3][CH2][NX3]),$([NX3][CH2][OX2]),$([CX4]([F,Cl,Br,I])([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])[CH2][OH1])]",* +22,Precursors of aldehydes and ketones,"[CX4]([OX2])([OX2])([CX4,a!r0])[CX4,a!r0]",*C(*)(O)O +23,Enol precursor of aldehydes and ketones,"[CX3]=[CX3]([#6,#1])[OX2]",*C(=C)O +24,Aromatic primary and secondary amines,"[a!r0][$([NX3H2]),$([NX3H1][CX4,a!r0])]",** +25,N-Haloimides,"[CX3](=[OX1])[NX3]([Cl,Br])[CX3](=[OX1])",*N(C=O)C=O +26,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl +27,Disullides,"[CX4,a!r0][SX2][SX2][CX4,a!r0]",*SS* +28,Phenyl carbonates,"c1ccccc1[OX2][CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)Oc1ccccc1 +29,Epoxides,[CX4]1[CX4][OX2]1,C1CO1 +30,1.2-Dicarbonyls,"[CX4,a!r0][CX3](=[OX1])[CX3](=[OX1])[#1,CX4,a!r0]",*C(=O)C(*)=O +31,Thiazolones,"[$([SX2]1[CX3]([CX4,a!r0])=[CX3]([CX4,a!r0])[CX3](=[OX1])[NX3]1([CX4,a!r0])),$([sX2]1[cX3]([CX4,a!r0])[cX3]([CX4,a!r0])[cX3](=[OX1])[nX3]1([CX4,a!r0]))]",* +32,"1, 2-Diamines","[CX4,a!r0][NX3H1][CX4][CX4][NX3H1][CX4,a!r0]",*[NH]CC[NH]* +33,Quaternary ammonium cation,"[NX4+]([CX4,a!r0])([CX4,a!r0])([CX4,a!r0])[CX4,a!r0]",*[N+](*)(*)* +34,Activated N-heterocycle halides,"[$(n1c([F,Cl])ncnc1),$(n1c([F,Cl])ccnc1),$(n1c([F,Cl])nccc1)]",* +35,Aromatic sulphuric acids and salts,"[a!r0][Sv4X3](=[OX1])[$([OH]),$([O-])]",*S(*)=O +36,Iso(thio)cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +37,Acid imides,"[NX3]1([#1,#6])[CX3](=[OX1])[CX3]([!R])=[CX3]([!R])[CX3]1(=[OX1])",*C1=C(*)C(=O)N(*)C1=O +38,Activated N-heterocycles,"[$(n1c([F,Cl,$([CX2]#[NX1])])nccc1),$(n1cnccc1([F,Cl,$([CX2]#[NX1])])),$(n1cncnc1([F,Cl,$([CX2]#[NX1])]))]",* +39,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +40,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC +41,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1 +42,Aldehydes and precursors,"[$([#1,#6;!$(C=C);!$(C#C)][CX3]([H])(=[OX1])),$([CX4;H1]([OX2])[OX2])]",* +43,"α, β-Unsaturated carbonyls","[CX3]=[CX3][CX3](=[OX1])[$([OX2]([CX3]=[OX1])[!#1]),$([#1][CX3]=[OX1]),$([NX3H2]([CX3]=[OX1])),$([NX3]([CX3]=[OX1])),$([CX4][CX3]=[OX1])]",*C(=O)C=C +44,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +45,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH] +46,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1 +47,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1 +48,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1 +49,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH] +50,Thiols,[#16X2H1],[SH] +51,Disulfides,*[#16X2][#16X2]*,*SS* +52,Diaryl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[a!r0],*C(=O)OOC(*)=O +53,Arylacyl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[A],*C(=O)OOC(*)=O +54,Haloamides,"[#6][CX3](=[OX1])[NX3]([F,Cl,Br,I])[#6]",*N(C)C(C)=O +55,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH] +56,"1,2-Dihydroxy aromatic compounds",[OH1]aa[OH1],[OH]*:*[OH] +57,"1,4-Dihydroxy aromatic compounds",[OH1]aaaa[OH1],[OH]*:*:*:*[OH] +58,2 or 4-Hydroxysubstituted alkylphenyl ether,"[$(c1c([OX2][CX4])c([OH1])ccc1),$(c1c([OX2][CX4])ccc([OH1])c1)]",* +59,Aromatic amines,"[a!r0][$([NX3H2]),$([NX3H1][#6])]",** +60,Aromatic amines precursors,"[$([a!r0][NH1][CX3](=[OX1])),$(c1c([NX2]=[NX2][a!r0])ccc([$([NX3]([CX4])([CX4])),$([NX3H1][CX4]),$([NH2]),$([OH1])])c1)]",* +61,Alkyl or aryl sylfonyl halides,"[CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +62,Sulfonamides,"c1c([Sv6X4](=[OX1])(=[OX1])[NX3H1][$([#1]),$([CX4]),$([a!r0])])ccc([NX3H2])c1",*[NH]S(=O)(=O)c1ccc([NH2])cc1 +63,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S +64,Hydrazines,"[#6&!$([CX3]=[OX1,SX1,NX2])][NX3H1][NX3H2,$([NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])])]",*[NH]C +65,Aromatic nitro (general),"[a!r0][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",** +66,Aromatic amine (general),[a!r0][NX3H2],*[NH2] +67,Three-membered heterocycles (general),"[NX3H1,SX2,OX2]1[CX4][CX4]1",*1CC1 +68,Nitroso (general),[NX2]=[OX1],N=O +69,Unsubstituted heteroatom-bonded heteroatom (general),"[$([NX3H2]-[#7]),$([NX3H2]-[#8]),$([OX2H1]-[#7]),$([OX2H1]-[#8])]",* +70,Azo-type (general),[NX2]=[NX2],N=N +71,Aliphatic halide (general),"[CX4][Cl,Br,I]",*C +72,Polycyclic aromatic system (general),"[$([aR3]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))])]",* +73,Aromatic nitroso (specific),[a!r0][NX2]=[OX1],*N=O +74,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O +75,Nitrosamine (specific),"[OX1]=[NX2][NX3]([#6,#1])[#6,#1]",*N(*)N=O +76,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1 +77,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1 +78,Azide (specific),"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +79,Diazo (specific),"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +80,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N +81,Aromatic hydroxylamine (specific),[a!r0][NX3H1][OH1],*[NH][OH] +82,Aliphatic halide (specific),"[Cl,Br,I][$([CX4]);!$([CX3](=[OX1,SX1,NX2]));!$([CH2][CH2][SX2,NX3])]",** +83,Carboxylic acid halide (specific),"[Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +84,Nitrogen and sulphur mustard (specific),"[Cl,Br,I][CH2][CH2][SX2,NX3]",*[CH2][CH2]* +85,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1 +86,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1 +87,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O +88,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O +89,Aliphatic N-nitro (additional),"[NX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1][O-]))]",*N +90,Diazonium (additional),"[$([a!r0][NX2+]#[NX1]),$([a!r0][NX2]#[NX1])]",* +91,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +92,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH] +93,1-Aryl-2-monoalkyl hydrazine (additional),[a!r0][NX3H1]-[NX3H1][CX4],*[NH][NH]C +94,Aromatic methylamine (additional),[a!r0][NX3;H1][CH3],*N[CH3] +95,Aromatic hydroxylamine ester (additional),[a!r0][NH][OX2][CX3](=[OX1]),*[NH]OC=O +96,Polycyclic planar system (additional),[*R1]1[*R2]2=[*R1][*R1]=[*R1][*R1]=[*R2]2[*R1][*R2]3=[*R1][*R1]=[*R1][*R1]=[*R2]13,*1*2=**=**=*2**2=**=**=*12 +97,Acyl halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +98,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +99,Monohaloalkene,"[CX3]([CX4,#1])([F,Cl,Br,I])=[CX3]([CX4,#1])[!F!Cl!Br!I]",*C(*)=C(*)* +100,S or N mustard,"[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +101,Propiolactones or propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +102,Epoxides and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +103,Aliphatic halogens,"[CX4;!H0][Br,Cl,I]",*C +104,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O +105,Simple aldehyde,"[CX3]([H])(=[OX1])[#1,#6&!$([CX3]=[CX3])]",*C([H])=O +106,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN +107,Aliphatic azo and azoxy,"[$([C,#1][NX2]=[NX2][C,#1]),$([CX3]=[NX2+]=N),$([CX3]=[NX2+]=[NX1-]),$([CX3-][NX2+]#[NX1]),$([CX3][NX2]#[NX1]),$(C[NX2]=N(=O)[*]),$(C[NX2]=[N+]([O-])[*])]",* +108,Isocyanate and isothiocyanate groups,"[NX2]=[CX2]=[OX1,Sv2X1]",*=C=N +109,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +110,Thiocarbonyl,"[$([NX3][CX3](=[Sv2X1])[NX3]),$([CX3;!$(C[OH]);!$(C[SH]);!$(C[O-]);!$(C[S-]);!$(CO[#6])](=[Sv2X1])[NX3])]",* +111,Heterocyclic polycyclic aromatic hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +112,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O +113,Azide and triazene groups,"[$([NX2!R]=[NX2!R][NX3!R]),$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",* +114,Aliphatic N-nitro group,"[NX3]([#1,C])([#1,C])[$([NX3+](=[OX1])[O-]),$([NX3](=O)=O)]",*N(*)* +115,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC +116,Aromatic nitroso group,[a!r0][NX2]=[OX1],*N=O +117,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +118,Coumarins and furocoumarins,"[$(c1cccc2c1oc(=O)cc2),$(C1=CC(=O)OC2=CC=CC=C12),$(C1=CC(=O)Oc2ccccc12)]",* +119,Halogenated benzene,"c1ccccc1[$([Br,Cl,F,I]);!$([Br,Cl,F,I]aa[Br,Cl,F,I]);!$([Br,Cl,F,I]aaa[Br,Cl,F,I]);!$([Br,Cl,F,I]aa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aaa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aa([OH])a([OH])aa[OH])]",*c1ccccc1 +120,Halogenated PAH,"[Br,Cl,F,I][$([cR1]1[cR1][cR1][cR1][cR1][cR1]1-[cR1]2[cR1][cR1][cR1][cR1][cR1]2),$([cR1]1[cR1][cR1][cR1][cR2]2[cR2]1[cR1][cR1][cR1][cR1]2)]",** +121,Halogenated dibenzodioxins,"[OR1]1[CR2]2=[CR1][CR1]=[CR1][CR1]=[CR2]2[OR1][CR2]3=[CR1][CR1]([F,Cl,Br,I])=[CR1][CR1]=[CR2]13",*C1=CC=C2OC3=CC=CC=C3OC2=C1 +122,Primary and secondary aromatic amines,"[$([a!r0][NX3;H2]),$([a!r0][NX3;H1][CH3]),$([a!r0][NX3;H1][CH2][CH3])]",* +123,Tertiary aromatic amines,"a[NX3]([$([CH3]),$([CH2][CH3])])[$([CH3]),$([CH2][CH3])]",*N(*)* +124,Secondary aromatic acetamides and formamides,"[$([a!r0][NX3;H1][CX3;H1](=[OX1])),$([a!r0][NX3;H1][CX3](=[OX1])[CH3])]",* +125,Nitroarenes,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=O)(=O))]",** +126,Nitrosoarenes,[a!r0][NX2]=[OX1],*N=O +127,Arylhydroxylamines,"[a!r0][NX3;H1][OX2][#1,#6]",*NO* +128,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O +129,N-Nitroso-N-alkylamides,"[CX4,a!r0][CX3](=[OX1])[NX3]([CX4])[NX2]=[OX1]",*C(=O)N(C)N=O +130,N-Nitroso-N-alkylureas,"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[NX3H1][CX4,a!r0]",*[NH]C(=O)N(C)N=O +131,N-Nitroso-N-alkylcarbamates (aka urethanes),"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)N(C)N=O +132,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O +133,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O +134,Benzylic halides,"[a!r0][CH2][Cl,Br,I]",*[CH2]* +135,Oxiranes and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +136,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +137,Alkyl esters of sulfonic and sulphuric acids,"[$([CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,a!r0][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])])]",* +138,Alkyl esters of phosphonic and phosphoric acids,"[$([CX4,a!r0][Pv5X4](=[OX1])([OX2][$([CH3]),$([CH2][CH3])])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,#1][OX2][Pv5X4](=[OX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])])]",* +139,Mixed alkyl esters of thiophosphoric acid,"[CX4][OX2][Pv5X4](=[SX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])]",*OP(=S)(O*)OC +140,Haloethylamines,"[NX3]([#1,#6])([#1,#6])[CH2][CH2][Cl,Br,I,F]",*[CH2][CH2]N(*)* +141,Haloalkylethers,"[$([#6][OX2][CH2][CH2][Cl,Br,I]),$([#6][OX2][CH2][Cl,Br,I])]",* +142,α-Halocarbonyl or a-halohydroxy,"[$([CX3](=[OX1])[CH2][Cl,Br,I]),$([CX4!H0]([OH1])[CH2][Cl,Br,I])]",* +143,Haloamines,"[#6][NX3]([#6])[Cl,Br,I,F]",*N(C)C +144,Allylic halides and alkoxides,"[CX3]=[CX3][CH2][$([Cl,Br,I]),$([OX2])]",*[CH2]C=C +145,Halogenated methanes,"[CX4]([H,F,Cl,Br,I])([H,F,Cl,Br,I])([H,F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)* +146,Vinyl halides,"[CX3]=[CX3H1][Cl,Br,I]",*[CH]=C +147,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O +148,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S +149,Alkyl esters of phosphonic or sulphonic acids,"[$([CX4,a][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]),$([CX4,a][Pv5X4](=[OX1])([OX2][#1,CX4])[OX2][CX4])]",* +150,Aromatic nitro groups,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=[OX1])=[OX1]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +151,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +152,Aromatic mono- and dialkylamino groups,"[a!r0][$([NX3H1][CH3]),$([NX3H1][CH2][CH3]),$([NX3]([CH3])[CH3]),$([NX3]([CH3])[CH2][CH3]),$([NX3]([CH2][CH3])[CH2][CH3]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +153,Alkyl hydrazines,"[NX3]([CX4])([#1,CX4])[NX3]([#1,CX4])[#1,CX4]",*N(*)N(*)C +154,Alkyl aldehydes,"[$([CX3]([H])(=[OX1])[#1,CX4])&!$([CX3]([H])(=[OX1])[CX3]=[CX3])]",* +155,Monohaloalkenes,"[CX3]([CX4,#1])(Cl)=[CX3]([!F!Cl!Br!I])[CX4,#1]",*C(*)=C(*)Cl +156,"β-Haloethyl N, S - mustards","[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +157,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl +158,Propiolactones and propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +159,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1 +160,Aromatic and aliphatic substituted primary alkyl halides,"[F,Cl,Br,I][CH2][CX4,a]",*[CH2]* +161,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O +162,Aliphatic and aromatic epoxides,"[$([CX4]1[OX2][CX4]1),$([#6]1=[#6][#8]1)]",* +163,Activated halo- or nitropyridines,"[$(c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])cc1),$(c1([F,Cl,Br,I,$(N(=O)=O)])ncccc1([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)]))]",* +164,2-Halo- or 2-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncccn1",*c1ncccn1 +165,4-Halo- or 4-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncncc1",*c1ccncn1 +166,Activated 2-halo- or 2-nitropyrazines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])nc1",*c1cnc(*)cn1 +167,Halo- or nitro s-triazines,"c1nc([F,Cl,Br,I,$(N(=O)=O)])ncn1",*c1ncncn1 +168,Formaldehyde and thioformaldehyde,"[CH2]=[OX1,SX1]",*=C +169,Aliphatic aldehydes and thioaldehydes,"[CX4][CX3H1]=[OX1,SX1]",*=[CH]C +170,Aromatic aldehydes,[a][CX3H1]=[OX1],*[CH]=O +171,"α, β-Unsaturated carbonyl and thiocarbonyl compounds","C(C)(C)=CC=[OX1,SX1]",*=CC=C(C)C +172,"α, β-Unsaturated ketones and thioketones","[C;!r5]([C;!r5])=[C;!r5][C;!r5](C)=[OX1,SX1;!r5]",*=C(C)C=CC +173,α-Diketones and α-dithiones,"[#6]C(=[OX1,SX1])C(=[OX1,SX1])[#6]",*=C(C)C(=*)C +174,β-Diketones and β-dithiones,"[#6]C(=[OX1,SX1])[CX4]C(=[OX1,SX1])[#6]",*=C(C)CC(=*)C +175,"C-Nitroso compounds, iso(thio)cyanates, (thio)cyanate esters","[#6][$([NX2]=O),$(N=C=O),$(OC#N),$(SC#N),$(N=C=S)]",*C +176,Primary alkyl amines,[CH2][NH2],[CH2][NH2] +177,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3] +178,"α, β-Unsaturated alkoxy","[$(CC(C)=[CH][CH2][OH]),$(CC=C(C)[CH2][OH])]",* +179,Three-membered heterocycles derivatives,"[CH,CH2,CH3;!$([CH2]CC=[O,S])]([F,Cl,Br,I,$(OS(=O)(=O)[#6,#1]),$(OS(=O)(=O)O[#6,#1])])[#6]1[O,N,SX2][#6]1",**C1*C1 +180,Lactones and their thio analogues,"C1C(=[O,S])[O,S][CH2,CH]1",*=C1**C1 +181,Esters of aromatic and unsaturated alcohols and their thio analogues,"[$(C=C),$(C#C),a][CH2,CH][O,S][$([CH]=O),$([CH]=S),$(C(C)=O),$(C(C)=S)]",**** +182,Aryloxy (arylthio) containing unsaturated compounds,"[$(C=C),$(C#C),a][CH2,CH][O,S][a]",**** +183,Aliphatic N-(thio)nitroso compounds,"[CH2,CH3][NX3][NX2]=[O,S]",*NN=* +184,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1 +185,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +186,Activated alkene (Michael acceptor) (1),"[CH2,CH]=[CH][$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*[CH]=* +187,Activated alkene (Michael acceptor) (2),"[CH2]=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C +188,Activated alkene (Michael acceptor),"aC=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C* +189,Activated alkine,"C#C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C#C +190,Activated conjugated dienes,"[CH2,CH]=[CH]C=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C[CH]=* +191,Alkenes containing a gem-dihalo-substituted terminal double bond,"C=C([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)=C +192,Ortho-disubstituted benzenes,"c1c([O,NH2,NH])c([O,NH2,NH])ccc1",*c1ccccc1* +193,Para-disubstituted benzenes,"c1c(=[O,NH2,NH])ccc(=[O,NH2,NH])c1",*=c1ccc(=*)cc1 +194,Haloanhydrides,"[F,Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +195,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1 +196,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21 +197,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +198,Phosphorus halogen derivatives (1),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#6])[#6]",*P(C)(C)=O +199,Phosphorus halogen derivatives (2),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#6]",*P(C)(O)=O +200,Phosphorus halogen derivatives (3),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#8]",*P(O)(O)=O +201,Phosphorus halogen derivatives (4),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#7])[#6]",*P(C)(N)=O +202,Phosphorus halogen derivatives (5),"[Pv5X4]([F,Cl,Br,I])([#6])([#6])=[SX1]",*P(C)(C)=S +203,Phosphorus halogen derivatives (6),"[Pv5X4]([#8])([#6])([F,Cl,Br,I])(=[SX1])",*P(C)(O)=S +204,Phosphorus halogen derivatives (7),"[Pv5X4](=[SX1])([F,Cl,Br,I])([#16])[#6]",*P(C)(S)=S +205,Phosphorus V derivatives,[Pv5X4]([!#1])([!#1])([!#1])=[NX2],*P(*)(*)=N +206,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC +207,Thiocyanates,[SX2][CX2]#[NX1],N#CS +208,Sulfonylhalides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +209,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O +210,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +211,Alkylsulfates,"[#6,#1][OX2,OH1][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]",**S(=O)(=O)OC +212,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O +213,All types of 3-valent phosphorus and similar (2),"[Pv3X3]([#8])([#8])[F,Cl,Br,I]",*P(O)O +214,All types of 3-valent phosphorus and similar (3),"[Pv3X3]([#8])([#6])[F,Cl,Br,I]",*P(C)O +215,All types of 3-valent phosphorus and similar (4),"[Pv3X3]([#6])([#6])[F,Cl,Br,I]",*P(C)C +216,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C +217,All types of 3-valent phosphorus and similar (6),"[Pv3X3]([#8])([#7])[F,Cl,Br,I]",*P(N)O +218,All types of 3-valent phosphorus and similar (7),"[Pv3X3]([#7])([#7])[F,Cl,Br,I]",*P(N)N +219,All types of 3-valent phosphorus and similar (8),"[#16][Pv3X3]([#6])[F,Cl,Br,I]",*P(C)S +220,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N +221,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C +222,Hydroxamic acid haloanhydrides,"[CX3]([#6])([F,Cl,Br])=[NX2][#8]",*C(C)=NO +223,Halothioanhydrides,"[#6][CX3](=[SX1])[F,Cl,Br,I]",*C(C)=S +224,Halocarbonates,"[#8][CX3](=[OX1])[F,Cl,Br,I]",*C(O)=O +225,Halocarbamates,"[#7][CX3](=[OX1])[F,Cl,Br,I]",*C(N)=O +226,Isocyanides,"[#6][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +227,Azides,"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +228,Thione esters,"[#6,#1][CX3](=[SX1])[OX2][#6]",*C(=S)OC +229,Acylsulfides,"[#6,#1][CX3](=[OX1])[SX2][#6]",*C(=O)SC +230,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S +231,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S +232,Peroxides,[OX2][OX2],OO +233,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS +234,Nitroso,[#6][NX2]=[OX1],CN=O +235,Nitrates,"[#6][OX2][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*OC +236,N-Nitro,"[#7][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*N +237,N-Nitroso,[#7][NX2]=[OX1],NN=O +238,Azo,[#6][NX2]=[NX2][#6],CN=NC +239,Azoxy,"[#6][$([NX2]=[NX3+]([O-])[#6]),$([NX2]=[NX3](=[OX1])[#6])]",*C +240,Nitroso dimers,"[$([#6][NX3+]([OX1-])=[NX3+]([OX1-])[#6]),$([#6][NX3](=[OX1])=[NX3](=[OX1])[#6])]",* +241,Sulfenyl halides,"[#6][Sv2X2][F,Cl,Br,I]",*SC +242,Sulfinyl halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +243,Diazonium salts,"[$([NX2+]#[NX1]),$([NX2]#N)]",* +244,Cyclic and linear haloamidines,"[CX3](=[#7])([#7])[Cl,Br,I]",*C(N)=N +245,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC +246,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C +247,Hydroxylamines,[OH1][NX3][#6],CN[OH] +248,N-Oxides,"[$([OX1-,OH1][#7X4+]([*])([*])([*])),$([OX1]=[#7X4v5]([*])([*])([*])),$([OX1]=[Nv5X3&!$([Nv5X3](=[OX1])=[OX1])](=[*])([*])),$([OX1-,OH1][#7X3+R](~[R])(~[R])),$([OX1]=[#7v5X3R](~[R])(~[R]))]",* +249,Aminals,N[CX4]N,NCN +250,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C +251,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C +252,α-Haloketones and similar,"[#6][CX3](=[OX1])[CX4][Cl,Br,I]",*CC(C)=O +253,β-Haloamines,"[NX3][CX4][CX4][Cl,Br,I]",*CCN +254,β-Halosulfides,"[Sv2X2][CX4][CX4][Cl,Br,I]",*CCS +255,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O +256,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O +257,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C +258,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O +259,Nitrovinyl,"[CX3]=[CX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +260,Acrylonitriles,[NX1]#CC=C,C=CC#N +261,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O +262,Vinylpyridines and similar,"[$(n1c([CX3]=[CX3])cccc1),$(n1cc([CX3]=[CX3])ccc1),$(n1ccc([CX3]=[CX3])cc1)]",* +263,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1 +264,Ketenes,[CX3]=[CX2]=[OX1],C=C=O +265,Allenes,C=C=C,C=C=C +266,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1 +267,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1 +268,Aziridines,[CX4]1[NX3][CX4]1,C1CN1 +269,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1 +270,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1 +271,Selen in chain,[Sev2X2],[SeH2] +272,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O +273,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N +274,Benzylhalogenides and similar,"c1ccccc1([CX4][Cl,Br,I])",*Cc1ccccc1 +275,Halomethyl ethers,"[F,Cl,Br,I][CX4][#8]",*CO +276,Halomethyl thioethers,"[F,Cl,Br,I][CX4][#16]",*CS +277,Halomethyl amines,"[F,Cl,Br,I][CX4][#7]",*CN +278,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O +279,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S +280,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S +281,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S +282,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S +283,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O +284,Positively charged N-heterocycles,[#7v4X3R],N +285,Organometallic compounds,"[$([Te]~[#6]),$([As]~[#6]),$([Ge]~[#6]),$([Hg]~[#6]),$([Co]~[#6]),$([Fe]~[#6]),$([Mn]~[#6]),$([Cr]~[#6]),$([Ti]~[#6]),$([Sn]~[#6])]",* +286,"Isothiazolinone, isothiazolinthione and their derivatives","[#6]1=,:[#6]C(=[OX1,SX1])N[SX2]1",*=C1C=CSN1 +287,Acyl and thioacyl halides,"[!$(C=C);!$(C#C)]C(=[O,SX1])[F,Cl,Br,I]",*C(*)=* +288,Imidoyl halides,"[!$(C=C);!$(C#C)]C(=N)[F,Cl,Br,I]",*C(*)=N +289,Esters of aromatic alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][a]",**C(*)=* +290,Acid anhydrides and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N]C(=[O,SX1,N])",*C(=*)*C=* +291,Esters of unsaturated alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,S,N])[O,S][$(C=C),$(C=N),$(C#C),$(C#N)]",**C(*)=* +292,"β-Lactones, β-lactams and their thio analogues","[#6]1C(=[O,S])[O,N,S][#6]1",*=C1*CC1 +293,Benzo-fused five-membered heterocycles,"[C,N,O,S,a]c1[n,o,s]c2ccccc2[n,o,s]1",*c1*c2ccccc2*1 +294,(Thio)carbonyl and imine derivatives of five-membered heterocycles,"[#6]1[#6](=[N,O,S])[#7,#8,#16][#6][#7,#8,#16]1",*=C1*C*C1 +295,Phthalic anhydrides and their thio and aza analogues,"[C,O]=[#6]1[#7,#8,#16][#6](=[O,N,SX1])c2ccccc12",*=C1*C(=*)c2ccccc21 +296,Acylating agents,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][CX4,O,S][$(C=O),a,$(C=C),$(C#C),$(C=N),$(C#N)]",***C(*)=* +297,Heteryl-substituted benzenes,"C1=[C,N][$(S(=O)(=O)),$(C=[N,O]),$(S=O)][C,N]=C1c2ccccc2",*1*=CC(c2ccccc2)=*1 +298,Cyclopentanone and cyclopentathione derivatives,"[CH2,CH]=C1C(=[OX1,SX1])**C1",*=C1**CC1=* +299,"Ortho-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])c([OH,NH2,NH,$(N=N),$(N(C)C)])ccc1",*c1ccccc1* +300,"Para-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])ccc([OH,NH2,NH,$(N=N),$(N(C)C)])c1",*c1ccc(*)cc1 +301,"Meta-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])cc([OH,NH2,NH,$(N(C)C)])cc1",*c1cccc(*)c1 +302,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH] +303,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1 +304,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1 +305,Haloethyl-substituted aromatic compounds,"C([F,Cl,Br,I])[CH2,CH][a]",**C* +306,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1 +307,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1 +308,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12 +309,vic-Difluoroalkyl group,"F[CH2,CH]C(F)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(F)*F +310,vic-Dichloroalkyl group,"Cl[CH2,CH]C(Cl)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Cl)*Cl +311,vic-Dibromoalkyl group,"Br[CH2,CH]C(Br)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Br)*Br +312,vic-Diiodoalkyl group,"I[CH2,CH]C(I)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(I)*I +313,Carboxylic acid anhydrides,"[$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6]1),$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6][#6]1)]",* +314,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl +315,Lactones,"[$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6]1),$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6][#6]1)]",* +316,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O +317,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC +318,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC +319,Cyclic sulfonic acid esters,"[$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +320,Cyclic sulfuric acid esters,"[$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +321,Halo acetates,"[F,Cl,Br,I][#6][CX3](=[OX1])[OX2H1]",*CC(=O)[OH] +322,Halo acetamides,"[F,Cl,Br,I][#6][CX3](=[OX1])[NX3]",*CC(N)=O +323,Halo ethers,"[$([F,Cl,Br,I]C[OX2]C),$([F,Cl,Br,I]CC[OX2]C)]",* +324,Haloethyl sulfides (S-mustard),"[F,Cl,Br,I][CX4][CX4][SX2]",*CCS +325,Haloethyl amines (N-mustard),"[F,Cl,Br,I][CH2][CH2][NX3]",*[CH2][CH2]N +326,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O +327,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N +328,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C +329,"α, β-Unsaturated nitro compounds","[#6]=[#6][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +330,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O +331,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C +332,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH] +333,"α, β-Unsaturated carbonyl compounds",[#6]=[#6][CX3](=[OX1])([!#1!$([OH1])]),*C(=O)C=C +334,Alkyl halide,"[*!$([a])&!$(C=C)&!$(C#C)][CX4][F,Cl,Br,I]",*C* +335,Aryl halide,"[a!r0][F,Cl,Br,I]",** +336,Halogenated allylic group,"[F,Cl,Br,I][CX4][CX3]=[CX3]",*CC=C +337,Halogenated benzylic group,"c[CX4][F,Cl,Br,I]",*Cc +338,Diazo compounds,"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +339,Organo metallic compounds,"[$([Cu][#6]),$([Ag][#6]),$([Au][#6]),$([Zn][#6]),$([Cd][#6]),$([Hg][#6]),$([Sn][#6]),$([Pb][#6]),$([As][#6]),$([Sb][#6])]",* +340,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C +341,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C +342,Iodine,II,II +343,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H] +344,Sulfoxides,[Sv4X3](=[OX1]),O=S +345,Sulfenyl iodides,[SX2][IX1],SI +346,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS +347,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S +348,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS +349,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH] +350,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1 +351,(Dithio) carbamates,"[OX2,SX2][CX3](=[OX1,SX1])[NX3]",*C(=*)N +352,Organotin compounds,[Sn][#6],C[Sn] +353,Pyrethroids,"[$(CC(=C[CH]1C([CH]1C(=O)OC1C(=C(C(=O)C1)CC=CC=C)C)(C)C)C),$(C(=C[CH]1C([CH]1C(=O)O[CH]1C(=C(C(=O)C1)CC=CC=C)C)(C)C)(C)C(=O)OC)]",* +354,Organophosphorothionate esters,"[Pv5X4](=[SX1])([OX2][#6])([OX2,SX2][#6])([OX2,SX2][#6])",C*P(=S)(*C)OC +355,Acetates,"[CH,$([C!R](=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R,NX3!R][$([a;r6]),$([a;r5]),$(C=C),$(C#C)]",***=* +356,Acyclic anhydrides,"[CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R][CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])]=[O,SX1]",*=***=* +357,Dialkyl carbamoylhalides,"[NH2!R,$([NH!R](C=O)[#6!R]),$(N(C=O)([#6!R])[#6!R])]C(=O)[F,Cl,Br,I]",*C(*)=O +358,Phosphonic acid halides,"[#6]O[P!R](=O)(O[#6])[F,Cl,Br,I,$(C#N)]",*P(=O)(OC)OC +359,Cyclopropenones,"[#6]1([#1,#6])=,:[#6]([#1,#6])-,:[#6]1=O",*C1=C(*)C1=O +360,β-Lactones,C1C(=O)OC1,O=C1CCO1 +361,Thio-lactones,C1C(=O)SC1,O=C1CCS1 +362,Azlactones,"C1=[O,SX2,NX2,CX3]CC(=[O,SX2])[O,SX2,NX3]1",*=C1*C=*C1 +363,Cyclic anhydrides,"[#6R,#8R,#16X2R][#6R](=[O,SX1])[#8R,#16X2R][#6R]([#6,#8R,#16X2])=[#8,#16X1]",*C(=*)*C(*)=* +364,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC +365,Polarised alkene-aldehydes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][CH]=O",*=*[CH]=O +366,Polarised alkene-ketones,"[$([$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[#6]);!$([#6X3]1=,:[#6X3H][CX3](=[OX1])[#6X3]=,:[#6X3][#6X3]1(=[OX1]));!$([CX3]1(=[OX1])[CX3](=[OX1])[#6X3]=,:[#6X3H][#6X3]=,:[#6X3]1)]",* +367,Polarised alkene-esters,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)O[#6]",*=*C(=O)OC +368,Polarised alkene-amides,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)*=* +369,Polarised alkene-nitros,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",**=* +370,Polarised alkene-cyanos,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C#N",*=*C#N +371,Polarised alkene-alkyl sulphonates,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)O[#6]",*=*S(=O)(=O)OC +372,Polarised alkene-alkyl sulfones,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)[#6]",*=*S(C)(=O)=O +373,Polarised alkene-alkyl sulfinyls,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][SX3](=O)[#6]",*=*S(C)=O +374,Polarised alkene-oximes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C=[NX2][OH]",*=*C=N[OH] +375,Polarised alkene-pyridines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncccc1),$(c1ccncc1)]",**=* +376,Polarised alkene-pyrazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]c1nccnc1",*=*c1cnccn1 +377,Polarised alkene-pyrimidines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncc1),$(c1ncccn1),$(c1cncnc1)]",**=* +378,Polarised akene-triazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1),$(c1nnncc1),$(c1cnnnc1)]",**=* +379,Azocarbonamides,"[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]C(=O)N=NC(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)N=NC(*)=O +380,Allyl alcohols,"[CH2,$([CH](=C)[#6])]=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",*=*[CH2][OH] +381,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH] +382,Polarised alkyne-aldehydes,"[CH,$(C(#C)[#6])]#C[CH]=O",*#C[CH]=O +383,Polarise alkyne-ketones,"[CH,$(C(#C)[#6])]#CC(=O)[#6]",*#CC(C)=O +384,Polarised alkyne-esters,"[CH,$(C(#C)[#6])]#CC(=O)O[#6]",*#CC(=O)OC +385,Polarised alkyne-amides,"[CH,$(C(#C)[#6])]#CC(=O)[$([NH2]),$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)C#* +386,Polarised alkyne-nitros,"[CH,$(C(#C)[#6])]#C[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C#* +387,Polarised alkyne-cyano,"[CH,$(C(#C)[#6])]#CC#N",*#CC#N +388,Polarised alkyne-alkyl sulphonates,"[CH,$(C(#C)[#6])]#CS(=O)(=O)O[#6]",*#CS(=O)(=O)OC +389,Polarised alkyne-alkyl sulfones,"[CH,$(C(#C)[#6])]#CS(=O)(=O)[#6]",*#CS(C)(=O)=O +390,Polarised alkyne-alkyl sulfinyls,"[CH,$(C(#C)[#6])]#C[SX3](=O)[#6]",*#CS(C)=O +391,Polarised alkyne-pyridines,"[CH,$(C(#C)[#6])]#C[$(c1ncccc1),$(c1ccncc1)]",*C#* +392,Polarised alkyne-pyrazines,"[CH,$(C(#C)[#6])]#Cc1nccnc1",*#Cc1cnccn1 +393,Polarised alkyne-pyrimidines,"[CH,$(C(#C)[#6])]#C[$(c1ncccn1),$(c1cncnc1),$(c1ncncc1)]",*C#* +394,Polarised alkyne-triazines,"[CH,$(C(#C)[#6])]#C[$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1)]",*C#* +395,Propargyl alcohols,"[CH,$(C(#C)[#6])]#C[CH2][OH]",*#C[CH2][OH] +396,Benzoquinones,"[$(C1(=O)[#6]=,:[#6]C(=O)[CH]=C1),$(C1(=O)C(=O)[#6]=,:[#6][CH]=C1)]",* +397,Quinone-imines,"[$(C1(=O)[#6]=,:[#6][$(C=[NH]),$(C=N[CX4])][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])]C=[CH][#6]=,:[#6]1)]",* +398,Quinone-diimines,"[$([CH]1=C[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][$(C=[NH]),$(C=N[CX4])]1),$([CH]1=C[$(C=[NH]),$(C=N[CX4])][$(C=[NH]),$(C=N[CX4])][#6]=,:[#6]1)]",* +399,Aminophenols,"[$(c1([OH])c[cH]c([NH2])cc1),$(c1([OH])c([NH2])cc[cH]c1)]",* +400,Benzenediamines,"[$(c1([NH2])c[cH]c([NH2])cc1),$(c1([NH2])c([NH2])cc[cH]c1)]",* +401,Quinone-methides,"[$(C1=CC(=O)[#6]=,:[#6]C1(=[CH][CX4])),$(C1(=[CH][CX4])C(=O)[#6]=,:[#6]C=C1)]",* +402,Pyranones,"[$([cH]1cc(=[O,NH])cc[o,n]1),$([cH]1cc(=[O,NH])[o,n]cc1),$(c1cc(=[O,NH])[o,n][cH]c1)]",* +403,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1 +404,Mono-aldehydes,"[CH2,$([CH](=O)[CX4]),$([CH](=O)c1a(*)caaa1),$([CH](=O)c1a(*)aaa1)]=O",*=O +405,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2] +406,"Di-substituted α,β-unsaturated alkenes (polarized by an aldehyde moiety)","[$(C(=C)([#6])[#6]);!$(C(=C)([#6])C=[CH2,CH])]=C[CH]=O",*=C[CH]=O +407,Di-substituted allyl alcohols,"C([#6])([#6])=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",CC(C)=*[CH2][OH] +408,"1,2-Dicarbonyls","[CH,$(C(=O)(C=O)[CX4]),$(C(=O)(C=O)c1a(*)aaaa1),$(C(=O)(C=O)c1a(*)aaa1)](=O)[CH,$(C(=O)(C=O)[#6]);!$(C(=O)(C=O)C=[CH2,CH]);!$(C(=O)(C=O)C#C)]=O",O=**=O +409,"1,3-Dicarbonyls","[CH,$(C(=O)([CX4]C=O)[CX4]),$(C(=O)([CX4]C=O)c1a(*)aaaa1),$(C(=O)([CX4]C=O)c1a(*)aaa1)](=O)[CX4][CH,$(C(=O)([CX4]C=O)[#6]);!$(C(=O)([CX4]C=O)C=[CH2,CH]);!$(C(=O)([CX4]C=O)C#C)]=O",O=*C*=O +410,Ethylenediamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][NH2]),$([NH]1[CH2][CH2][NH][CH2][CH2]1)]",* +411,Ethanolamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][OH]),$([NH]1[CH2][CH2]O[CH2][CH2]1)]",* +412,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1 +413,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1 +414,Alkyl halides,"[CH3,$([CH2]([F,Cl,Br,I])[#6]),$([CH]([F,Br,Cl,I])([#6])[#6]);!$([CH2,CH]C=O);!$([CH2,CH][CX4][NX3,SX2]);!$([CH2,CH][CX4][F,Cl,Br,I])][F,Cl,Br,I]",** +415,Alkyl diazos,"[CH3,$([CH2](N=N)[#6]),$([CH](N=N)([#6])[#6])][NX2]=[NH,$(N(=N)[#6])]",*N=* +416,Alkyl sulfates,"[#6]OS(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(=O)(=O)OC +417,Alkyl sulphonates,"[#6]S(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(C)(=O)=O +418,Alkyl (thio)phosphates,"[#6][O,SX2]P(=[O,SX1])([O,SX2][#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(*C)*C +419,Alkyl (thio)phosphonates,"[#6][O,SX2]P(=[O,SX1])([#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(C)*C +420,Allyl acetates,"[#6]C(=[O,SX1])[O,SX2][CH2,$([CH]([O,SX2])[#6])][c,CX3,CX2]",***C(=*)C +421,α-Halocarbonyls,"[$([CH]=[O,SX1]),$(C([#6])=[O,SX1])][CH2,$([CH](C=[O,SX1])[#6])][F,Cl,Br,I]",*** +422,α-Haloalkynes,"[CH,$(C(#C)[#6])]#C[$([CH2](C#C)[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH](C#C)([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*C#* +423,α-Halobenzyls,"[c][$([CH2]([c])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH]([a])([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*c +424,Sulfuranes,C1[SX2]C1,C1CS1 +425,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1 +426,Nitrosoureas,"[NX3]C(=O)[$([NH](C=O)[NX2]=O),$(N(C=O)([#6])[NX2]=O)]",*C(N)=O +427,Nitrosoguanidines,"[NX3]C(=[NH])[$([NH](C=[NH])[NX2]=O),$(N(C=[NH])([#6])[NX2]=O)]",*C(N)=N +428,N-Acytoxy-N-acetylphenyls,"[a][NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)* +429,N-Acytoxy-N-alkoxyamides,"[#6]O[NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)OC +430,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O +431,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O +432,Aromatic sulphonic acids,[a][SX4](=O)(=O)[OH],*S(=O)(=O)[OH] +433,Isothiazol-3-ones,"[cH,$(c(c)([sX2])[#6])]1[cH,$(c(c)(c=O)[#6])]c(=O)[nH,$(n(c=O)([sX2])[#6])][sX2]1",O=c1*:*s*1 +434,Isothiazolin-3-ones,"[CH2,$([CH](C)([SX2])[#6])]1[CH2,$([CH](C)(C=O)[#6])]C(=O)[NH,$(N(C=O)([SX2])[#6])][SX2]1",O=C1**S*1 +435,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl +436,Polarized alkenes with a halogen leaving group,"C=[CH][F,Cl,Br,I]",*[CH]=C +437,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C +438,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C +439,Polarized alkenes with an alkyl (thio)phosphonate leaving group,"C=[CH]OP(=[O,SX])(O[#6])[#6]",*=P(C)(OC)O[CH]=C +440,Polarized alkenes with an alkyl (thio)phosphate leaving group,"C=[CH]OP(=[O,SX])(O[#6])O[#6]",*=P(OC)(OC)O[CH]=C +441,Mustards,"[NX3,SX2][CH2,$([CH]([NX3,SX2])([CX4])[CX4])][CH2,$([CH]([CX4])([Cl,Br,I])[CX4])][Cl,Br,I]",**** +442,"1,2-Dihaloalkanes","[Cl,Br,I][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][Cl,Br,I]",**** +443,Activated pentafluorobenzenes,"c1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-]),$([CH]=O),$(C#N),$(C(=O)[CH3])])c(F)c(F)c(F)c(F)c1(F)",*c1c(F)c(F)c(F)c(F)c1F +444,Formaldehyde releasers (1),"[$(O1COCC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C1),$([OX2H1]CC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C[OX2H1])]",* +445,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH] +446,Formaldehyde releasers (3),"C1(=[OX1])[NX3H1]C(=[OX1])[NX3H1][CX4]1(C[OH1])[NX3H1][CX3](=[OX1])[NX3!H0][#1,#6]",*NC(=O)[NH]C1(C[OH])[NH]C(=O)[NH]C1=O +447,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH] +448,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1 +449,"Hydrazine, hydrazides","[#6,#1][NX3H1][NX3H1][#6,#1]",*[NH][NH]* +450,Nitrobenzenes,"a[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",** +451,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21 +452,Benzylamines,"[#1,CX4!R][NX3]([#1,CX4!R])[CH2]c1ccccc1",*N(*)[CH2]c1ccccc1 +453,Propargyl amines,"[#1,CX4,$(c1ccccc1)][CX2]#[CX2][NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*C#CN(*)* +454,Cyclopropyl amines,"[CX4]1[CX4][CX4]1[NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*N(*)C1CC1 +455,"N-Substituted-4-aryl-1,2,3,6-tetrahydropyridines","[NX3]1([CX4!R])[CX4][CX3]=[CX3](c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2=CCN(C)CC2)c(*)c1* +456,N-Substituted-4-arylpiperidin-4-ol,"[NX3]1([CX4!R])[CX4][CX4][CX4]([OH1])(c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2([OH])CCN(C)CC2)c(*)c1* +457,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O +458,Hydantoins (glycolylurea),"[NX3H1]1[CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NX3H1][CX3]1(=[OX1])",*C1(*)[NH]C(=O)[NH]C1=O +459,Thioureas,"[#1,#6][NX3]([#1,#6])[CX3](=[SX1])[#7]",*N(*)C(N)=S +460,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O +461,Ortho- or parahydroquinones,"[$(c1([OH1])c([OH1])cccc1),$(c1([OH1])ccc([OH1])cc1)]",* +462,Ortho- or paraquinones,"[$([#6]1(=[OX1])-,:[#6]=,:[#6]-,:[#6](=[OX1])-,:[#6]=,:[#6]1),$([#6]1(=[OX1])-,:[#6](=[OX1])-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)]",* +463,Ortho- or paraalkylphenols,"[$(c1([OH1])c([CX4]([#1,#6])[#1,#6])cccc1),$(c1([OH1])ccc([CX4]([#1,#6])[#1,#6])cc1)]",* +464,Quinone methide,"[$([OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]-,:[#6X3]1=[CX3]([#1,#6])[#1,#6]),$([OX1]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[CX3]([#1,#6])[#1,#6])-,:[#6]=,:[#6]1)]",* +465,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1 +466,3-Methylene indoles,"c1ccc([nX3]2([#1,#6]))c(c([CH2][#1,#6])c2)c1",*[CH2]c1cn(*)c2ccccc12 +467,Furans,c1ccc[oX2]1,c1ccoc1 +468,Thiophenes,c1ccc[sX2]1,c1ccsc1 +469,Thiazoles and 2-amino derivatives,"[$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([#1,CX4!R])[sX2]1),$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([NX3]([#1,CX4!R])[#1,CX4!R])[sX2]1)]",* +470,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O +471,2- or 4-Halopyridines,"[$(n1c([Cl,Br,I,F])cccc1),$(n1cccc([Cl,Br,I,F])cc1)]",* +472,Alkynes,"[#6][CX2]#[CX2][#1,#6]",*C#CC +473,Alkylhalides,"[$([CX4]([F,Cl,Br,I])([H,!F!Cl!Br!I])([H,!F!Cl!Br!I])[H,!F!Cl!Br!I]),$([CX4]([#6])([F,Cl,Br,I])([F,Cl,Br,I])[H,!F!Cl!Br!I])]",* +474,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH] +475,Fluoroethyl ethers and amines,"[$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][OX2][#1,#6]),$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][NX3][#6])]",* +476,Three-membered heterocycles,"[#6]1~[#6][#7,#8,#16]1",*1C~C1 +477,Thioles,[Sv2X2H1],[SH] +478,Chlor(brom)anhydrides,"[CX3](=[OX1])[Cl,Br]",*C=O +479,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O +480,Trihalogensubstituted ketones,"[CX3](=[OX1])[CX4]([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C=O +481,Monohalogen substituted ketones,"[CX3](=[OX1])C[Cl,Br,I]",*CC=O +482,Sulphonhalogenanhydrides,"S(=[OX1])(=[OX1])[F,Cl,Br,I]",*S(=O)=O +483,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH] +484,Phosphorus,P,P +485,Selen,[Se],[SeH2] +486,Bor,B,B +487,Silicium,[Si],[SiH4] +488,"Isocyanates, isothiocyanates","[NX2]=[CX2]=[OX1,SX1]",*=C=N +489,Thione,[CX3]=[SX1!R],C=S +490,β-halogen substituted carbonyls,"[CX3](=[OX1])CC[F,Cl,Br,I]",*CCC=O +491,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH] +492,gem-Dihalo propane and cyclopropane,"CC([Cl,Br,I])([Cl,Br,I])C",*C(*)(C)C +493,Activated halides (o-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cc[F,Cl,Br]",*cc* +494,Activated halides (p-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cccc[F,Cl,Br]",*cccc* +495,Activated halides (α-halogen substituted N-heterocycles),"nc[F,Cl,Br]",*cn +496,Activated halides (γ-halogen substituted N-heterocycles),"nccc[F,Cl,Br]",*cccn +497,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S +498,Barbiturates,"N1C(=[OX1,SX1])NC(=[OX1,SX1])C(=C)C1(=[OX1,SX1])",*=C1NC(=*)C(=C)C(=*)N1 +499,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2] +500,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O +501,Crown ethers,[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C,*C~C*C~C*C~C*C~C*C~C*C~C +502,Coumarins (1),"c1cccc2c1oc(=O)c([$(C=[OX1]),$(C=[SX1]),$(S=[OX1]),$(C#[NX1]),F,Cl,Br,I,$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]));!$([CX3](=[OX1])[OH1])])[c!H0]2",*c1cc2ccccc2oc1=O +503,Coumarins (2),"[cH1]1[cH1]c2c3[cH1][cH1]c(cc3oc(=O)c2[cH1]c1[OX2][$([CH2]),$([CH3])])[OX2][C!H0]",*Oc1[cH][cH]c2c([cH]1)c(=O)oc1cc(OC)[cH][cH]c12 +504,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1 +505,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1 +506,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1 +507,Coumarins (6),"c1([F,Cl,Br,I])cc([F,Cl,Br,I])cc2c1oc(=[NX2H1])c([CX3](=[OX1])[NH2])[c!H0]2",*c1cc(*)c2oc(=N)c(C([NH2])=O)cc2c1 +508,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1 +509,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1 +510,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O +511,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N +512,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O +513,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N +514,o-Quinones (3),"CC(=[OX1])C(=[OX1])[#6,#7]",*C(=O)C(C)=O +515,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S +516,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12 +517,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O +518,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH] +519,N-N Single bound not in a ring,[N!R][N!R],NN +520,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC +521,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O +522,Acyl and sulfinyl cyanide,"[$(C(=[OX1])[CX2]#[NX1]),$(S(=[OX1])[CX2]#[NX1])]",* +523,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1 +524,Hydrazine and other nucleophilic NH2-groups,"[NX3H2][#7,#8]",*[NH2] +525,Activated halo- and sulfonyl-aromatics,"c1([F,Cl,Br,I,$(C(C)=NO),$([CX2]#[NX1]),$([CX3]=[OX1]),$([CX4](F)(F)F),$([SX4](=[OX1])=[OX1]);!$([CX3](=[OX1])[OH1])])na([F,Cl,Br,I,$([SX4](=[OX1])(=[OX1])C)])a([!#7])a([!#7])a1",**1:*c(*)n*(*):*:1* +526,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O +527,Acyclic gem-dihalosubstituted carbon atom,"[C!R]([Cl,Br,I])[Cl,Br,I]",*C* +528,Imines,"[N!R]=[C,N]",*=N +529,Michael acceptors (carbonyl containing acrylonitrile derivatives),C[CX3H1]=[CX3!R](C(=[OX1])[!#1]~[!#1])[CX2]#[NX1],*~*C(=O)C(C#N)=[CH]C +530,Over halogenated rings,"a1c([F,Cl,Br,I])c([F,Cl,Br,I])ac([F,Cl,Br,I])a1",*c1*:*c(*)c(*)*1 +531,o-Quinones (1),"[CX3]1(=[!#1!#6])[CX3](=[!#1!#6])[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1",*=C1C=CC=CC1=* +532,o-Quinones (2),CC(=[!#1!#6;!R])C(=[!#1!#6;!R])C,*=C(C)C(=*)C +533,o-Quinones (4),CC(=[!#1!#6;!R])S(=[OX1])(=[OX1]),*=C(C)S(=O)=O +534,p-Quinones (1),"[#6X3]1=,:[#6X3][CX3](=[!#1!#6])[#6X3]=,:[#6X3][#6X3]1(=[!#1!#6])",*=C1C=CC(=*)C=C1 +535,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3 +536,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3 +537,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1 +538,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23 +539,Acid anhydrides and analogues,[!#1](=O)O[!#1]=O,O=*O*=O +540,Acyl halides and analogues,"[C,S](=[O,S])[F,Br,Cl,I]",**=* +541,Cyano carbonyl compounds ,N#CC(=O),N#CC=O +542,Methylendiamines (1),"[!$([C,S]=O)]N([!$([C,S]=O)])[CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*N(*)CN(*)* +543,Methylendiamines (2),"[!$([C,S]=O)][NH][CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*[NH]CN(*)* +544,Methylendiamines (3),"[!$([C,S]=O)][NH][CX4][NH][!$([C,S]=O)]",*[NH]C[NH]* +545,N-Acetoxy amines and their thio analogues,"[#7][#8][C,S]=O",NO*=O +546,α-Halogen substituted N-heterocycles,"[F,Br,Cl,I]-cn",*cn +547,Activated haloaromatics,"[F,Cl,Br,I][$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",** +548,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N +549,Benzyl ammoniums,cC[NX4+],cC[N+] +550,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O +551,Cations,"[#6+,#17+,#53+,#15+,#16+]",* +552,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N +553,Halogen-bonded heteroatoms,"[!#1&!#6][F,Cl,Br,I]",** +554,Cumulated double bonds,"[C,N]=C=[C,O,N,S]",*=C=* +555,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O +556,Singel acyclic N-N bonds,[#7]!@-N,N~N +557,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N +558,Activated double bonds (2),[!c][C!H0]=CC=O,*C=CC=O +559,Activated double bonds (3),"[C!H0]=C[S,N]=O",C=C*=O +560,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O +561,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS +562,Acetoxy group attached to the substituted aromatic ring,"C(=O)O[$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",*OC=O +563,"Oxetanes, thietanes","C1[O,S]CC1",*1CCC1 +564,Trihalomethyl ketones,"CC(=O)C([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C(C)=O +565,Phosphonates,[#6]P(=O)O[#6],COP(C)=O +566,Phosphorus containing compounds ,"NP(=[N,O,S])",*=PN +567,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +568,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O +569,"C, N, O, P and S atoms in unusual valence states","[#6!v4+0,#7!v3+0,#8!v2+0,#15!v3!v5+0,#16!v2!v4!v6+0]",* +570,Sulfurous acid esters,[!#1]OS(=O)O,*OS(O)=O +571,Heteroatom-bonded thiocarbonyls,"C(=S)[O,S,N]",*C=S +572,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS +573,Thiocarbonyls,C(=S)[!#1!H0],*C=S +574,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O +575,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F +576,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O +577,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1 +578,Double acyclic N=N and N=S bonds,"[NR0,SR0]=[NR0]",*=N +579,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1 +580,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC +581,"Iodosos, chlorosos","[Cl,I]=O",*=O +582,Acid grops,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +583,Phosphocyanates,PC#N,N#CP +584,α-Hydroxy nitriles,N#CC[OH],N#CC[OH] +585,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O +586,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO +587,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N +588,Nitrites,[!#1]ON=O,*ON=O +589,Nitroso compounds,[NX2]=O,N=O +590,"Any atoms except organogens, halogens, P, S, K, Na, Mg, Ca",[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +591,Double P=S and P=C bonds,"P=[S,#6]",*=P +592,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F +593,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +594,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1 +595,Phosphorus derivatives,[P!v5],P +596,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C +597,Carboxylic acid esters,[CX4]C(=O)O[#6][!#1],*COC(C)=O +598,"N,N-Dialkyl aniline derivatives (1)","[CX4][NX3]([CX4])c1cc([$([CX4]),$(O[CX4][CX4])])c([#7])[cH]c1",*c1cc(N(C)C)c[cH]c1N +599,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1 +600,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1 +601,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1 +602,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1 +603,"N,N-Dialkyl aniline derivatives (4)","[CX4]N([CX4])c1ccc([CX4][$([OH]),$(C=[C!H0]),$(N[CX4])])cc1",*Cc1ccc(N(C)C)cc1 +604,"N,N-Dialkyl aniline derivatives (5)","[CX4]N([C!H0])c1[cH][cH]c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH][cH]1 +605,"N,N-Dialkyl aniline derivatives (6)","[CX4]N([C!H0])c1[cH]c([CX4])c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH]c1C +606,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O +607,Five-membered heterocycles (1),"C1(=C)C(=O)[#7,#8,#15,#16]N=C1",C=C1C=N*C1=O +608,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O +609,Six-membered heterocycles,"[#7,#8,#15,#16]~C1~[#7,#8,#15,#16]~C[#7,#8,#15,#16][CX3](=[#7,#8,#15,#16])[CX3]1(=[C!H0])",*~C1C(=C)C(=*)*C~*~1 +610,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1 +611,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC +612,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH] +613,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1 +614,"1,2-Diimines, 1,2-diketones and their thio- and phospho-analogues","[#6][#6](=[#7,#8,#15,#16])[#6](=[#7,#8,#15,#16])[#6,Sv6]",*C(=*)C(=*)C +615,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21 +616,NH-Indoles,"[nH]1c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1[nH]c2ccc[cH]c2c1C +617,N-Alkyl substituted indoles,"n1([CH2])c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1c(C)c2[cH]cccc2n1[CH2] +618,Macrocycles,"[*r10,*r11,*r12,*r13,*r14,*r15,*r16,*r17,*r18,*r19,*r20,*r21,*r22,*r23,*r24,*r25,*r26,*r27,*r28,*r29,*r30]",* +619,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH] +620,N-Allophanoylamides and their thio analogues,"NC(=[O,S])NC(=[O,S])NC=[O,S]",*=CNC(=*)NC(=*)N +621,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1 +622,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21 +623,N-Phenylpyrrole derivatives,N1(c2[!#1]cccc2)C([CX4])=C[C!H0]=C1[CX4],CC1=CC=C(C)N1c1cccc*1 +624,"Quinones, quinone-(di)imines and their thio- and phospho-analogues","[#7,#8,#15,#16]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[#7,#8,#15,#16])-,:[#6]=,:[#6]1",*=C1C=CC(=*)C=C1 +625,Five-membered heterocycles (2),"[#7]=C1S[CH]=C([$([CH2]),$(c:c)])N1",*C1=[CH]SC(=N)N1 +626,Five-membered heterocycles (3),"[#7]=C1SC([$([CH2]),$(C=O)])=C([$([CH2]),$(c:c)])N1",*C1=C(*)SC(=N)N1 +627,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c +628,Acethylenes,"[CH2,CH3]C#C[CH2,CH3]",*C#C* +629,α-Halonitriles,"[F,Cl,Br,I][CX4][CX2]#[NX1]",*CC#N +630,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N +631,Benzthiozolium like compounds,"[#7,#8,#16]1-,:[#6]=,:[#6]-,:[#7+]2=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6]21",*1C=C[N+]2=**=**=C12 +632,Cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +633,Di-carbonyls,"[#1,#6][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(*)=O +634,Haloalkyl,"[C!H0]([#1,#6,#7,#8,#16])[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])[Cl,Br,I]",*CC(*)(*)* +635,"Haloalkyl group attached to S, N or O atoms","[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])([Cl,Br,I])[#7,#8,#16]",*C(*)(*)* +636,Haloethylenes,"[CX3!H0]=[CX3]([#1,Cl,Br,I])[Cl,Br,I]",*C(*)=C +637,Halopyridines,"c1([F,Cl,Br,I])n[c,n][c,n][c,n][c,n]1",*c1*:*:*:*n1 +638,Heptanes,"[CH3][CH2][CH2][CH2][CH2][CH2][CH2,CH3]",*[CH2][CH2][CH2][CH2][CH2][CH3] +639,N-Oxides (six-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1)]",* +640,N-Oxides (five-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1)]",* +641,Phosphorus cations,[#15+],[PH4+] +642,Peroxide like compounds,"O[F,Cl,Br,I]",*O +643,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O +644,Double P=O bonds,[#15]=O,O=P +645,Pyridinium like compounds,"[#6][#7+]1=,:[#6]-,:[#6,#7]=,:[#6]-,:[#6,#7]=,:[#6]1",C[N+]1=C*=C*=C1 +646,Quinolizinium like compounds,"[#6,#7]1=,:[#6,#7]-,:[#6,#7]=,:[#7+]2-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6]2=,:[#6,#7]1",*1=**=[N+]2*=**=*C2=*1 +647,Sulfates,"[Sv6X4](=[OX1])(=[OX1])([#8])[#6,#8]",*S(O)(=O)=O +648,Thio aldehydes,"[#6,#1][CX3]([H])=[SX1]",*C([H])=S +649,Thio halogens,"[#16][F,Cl,Br,I]",*S +650,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH] +651,Thiozolium like compounds,"[#6][#7+]1=,:[#6]-,:[#7,#8,#16]-,:[#6]=,:[#6]1",C[N+]1=C*C=C1 +652,Acyl Halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +653,Sulphonyl Halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +654,Alkyl Halides,"[CX4][F,Cl,Br,I]",*C +655,Activated Halides,"[$(c([F,Cl,Br,I])c[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])aac[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])n),$(c([F,Cl,Br,I])aan)]",* +656,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +657,Aldehydes (including aminoformyl moieties),"[$([#1,#6][CX3]([H])=[OX1]),$([#7]([#1,#6])([#1,#6])[CX3H1]=[OX1])]",* +658,Nitrosos,[NX2]=[OX1],N=O +659,Picrates,"c1([OH1,O-])c([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])",*c1cc(*)c(*)c(*)c1 +660,Perchlorates (periodates),"[$([Clv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-]),$([Iv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-])]",* +661,Simple anilines and phenols,"[$(c1([NX3]([#1,#6])[#1,#6])ccccc1),$(c1([OH1])ccccc1)]",* +662,Vinyl ketones (Michael acceptors),[CX3]([!R])([!R])=[CX3][CX3](=[OX1])[!$([OH1])!$([OX2][CH2])!$([NH2])!$([CX2]#[NX1])!a],*C(=O)C=C(*)* +663,Metals,[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +664,Non-organic chemistry atoms,[!#6!#1!#7!#8!#9!#17!#35!#53!#15!#14!#16],* +665,Atoms not supported in ALOGPS program,[!#1!#6!#7!#8!#16!#15!#9!#17!#35!#53],* +666,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F +667,Carbonyl compouns: aldehydes or ketones,"[$([H][CX3]([#1,#6])=[OX1]),$([#6&!$(C#N)][CX3](=[OX1])[#6&!$(C#N)])]",* +668,Thiocarbonyl compounds: thioaldehydes or thioketones,"[$([#1,#6][#6X3](=[SX1])[#1,#6]),$([#6]=[CX2]=[Sv2X1])]",* +669,Thioaldehydes,"[#1][CX3]([#1,#6])=[SX1]",*C([H])=S +670,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S +671,Hydrazones,"[CX3]([#1,#6])([#1,#6])=[NX2][#7X3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)* +672,Semicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=O)N(*)* +673,Thiosemicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=S)N(*)* +674,Oximes,"[#1,#6][CX3]([#1,#6])=[NX2][OH1]",*C(*)=N[OH] +675,Oxime ethers,"[#1,#6][CX3]([#1,#6])=[NX2][OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NOC +676,Ketene acetal derivatives,"[#1,#6][CX3]([#1,#6])=[CX3]([!#6!#1])[!#6!#1]",*C(*)=C(*)* +677,Carbonyl hydrates,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OH1]",[OH]*[OH] +678,Hemiacetals / Hemiketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*[OH] +679,Acetals / Ketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*OC +680,Hemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,*])[#1,*]",*O*N(*)* +681,Thiohemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[NX3]([#1,*])[#1,*]",*S*N(*)* +682,Thioacetals / Thioketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[SX2,OX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)]",C**SC +683,Enols,"[CX3]([#1,#6])([#1,#6])=[CX3]([OH1])[#1,#6]",*C(*)=C(*)[OH] +684,Enolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([OX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]",*C(*)=C(*)OC +685,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH] +686,Alcohols,"[$([CX4][OH1])&!$(C([OH1])[#7,#8,#15,#16,F,Cl,Br,I])]",* +687,Primary alcohols,"[$([#6][CH2][OH1]),$([CH3][OH1])]",* +688,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH] +689,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH] +690,"1,2-Diols","[CX4]([OH1])([#1,#6])([#1,#6])[CX4]([OH1])([#1,#6])([#1,#6])",*C(*)([OH])C(*)(*)[OH] +691,"1,2-Aminoalcohols","[CX4]([#1,#6])([#1,#6])([OH1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([CX4][CX4][OH1])[#6&!$([CX3]=[OX1,SX1,NX2,C])])]",*C(*)(*)C(*)(*)[OH] +692,Phenols,c[OH1],c[OH] +693,Diphenols,"[$(c([OH1])c([OH1])),$(c([OH1])[aR1]c([OH1])),$(c1([OH1])aac([OH1])aa1)]",* +694,Enediols,"[CX3]([#1,#6])([OH1])=[CX3]([#1,#6])([OH1])",*C([OH])=C(*)[OH] +695,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC +696,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc +697,Diarylethers,c[OX2&!$([OX2r3])]c,cOc +698,Hydroperoxides,"[#1,#6][OX2][OX2H1]",*O[OH] +699,Hydrazine derivatives,"[$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])][$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])]",** +700,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +701,Primary aromatic amines,[NX3H2]c,c[NH2] +702,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C +703,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C +704,Secondary aromatic amines,[NX3H1](c)c,c[NH]c +705,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C +706,Tertiary mixed amines (aryl alkyl),"c[NX3]([CX4&!$([CX4]([NX3])[O,N,S,P])])[c,CX4&!$([CX4]([NX3]c)[O,S,N,P])]",*N(c)C +707,Quaternary ammonium salts,"[NX4,NX4+]([#6])([#6])([#6])[#6]",C*(C)(C)C +708,"Halogen derivatives (alkyl, alkenyl, aryl)","[CX4,CX3,c;!$([#6]=[OX1])][F,Cl,Br,I]",** +709,Aryl fluorides,aF,*F +710,Aryl chlorides,aCl,*Cl +711,Aryl bromides,aBr,*Br +712,Aryl iodides,aI,*I +713,Organolithium compounds,[Li][#6],[Li]C +714,Organomagnesium compounds,[Mg][#6],C[Mg] +715,Carboxylic acid derivatives,"[#1,#6][CX3](=[OX1])[!#1!#6!$([SH1,SX2])]",*C(*)=O +716,Carboxylic acid salts,"[#1,#6][CX3](=[OX1])[OX1-]",*C(=O)[O-] +717,Carboxylic acid amides,"[#1,#6][CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=O)N(*)* +718,Carboxylic acid primary amides,"[#1,#6][CX3](=[OX1])[NX3H2]",*C([NH2])=O +719,Carboxylic acid secondary amides,"[#1,#6][CX3](=[OX1])[NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)[NH]C +720,Carboxylic acid tertiary amides,"[#1,#6][CX3](=[OX1])[NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)N(C)C +721,Lactams,"[#6R][CX3R](=[OX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=O +722,Carboxylic acid hydrazides,"[$([#6,#1][#6X3](=[OX1])[#7X3&!$([#7X3]([*]=[OX1,SX1])[#7X3]([*]=[OX1,SX1]))][#7X3]),$(C1(=O)[NX3][NX3]C(=O)cc1)]",* +723,Carboxylic acid azides,"[#1,#6][CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C(*)=O +724,Hydroxamic acids,"[#1,#6][CX3](=[OX1])[NX3][OH1]",*C(=O)N[OH] +725,Carboxylic acid amidines,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,N])]",*N=C(*)N(*)* +726,Carboxylic acid amidrazones,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)N(*)N(*)* +727,Nitriles,"[#1,#6&!$([CX3]=[OX1,SX1])][CX2]#[NX1]",*C#N +728,Acyl fluorides,"[#1,#6][CX3](=[OX1])F",*C(=O)F +729,Acyl chlorides,"[#1,#6][CX3](=[OX1])Cl",*C(=O)Cl +730,Acyl bromides,"[#1,#6][CX3](=[OX1])Br",*C(=O)Br +731,Acyl iodides,"[#1,#6][CX3](=[OX1])I",*C(=O)I +732,Acyl cyanides,"[#1,#6][CX3](=[OX1])[CX2]#[NX1]",*C(=O)C#N +733,Imido esters,"[#1,#6][CX3](=[NX2][#1,#6])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*N=C(*)OC +734,Thiocarboxylic acid derivatives,"[$([#1,#6][CX3](=[SX1])[!#1!#6]),$([#1,#6][CX3](=[OX1])[SX2])]",* +735,Thiocarboxylic acids,"[$([#1,#6][CX3](=[SX1])[OH1,SH1]),$([#1,#6][CX3](=[OX1])[SH1])]",* +736,Thiocarboxylic acid esters,"[$([#1,#6][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#1,#6][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +737,Thiolactones,"[$([#6R][CX3R](=[SX1])[OX2R,SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])]),$([#6R][CX3R](=[OX1])[SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])])]",* +738,Thiocarboxylic acid amides,"[#1,#6][CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=S)N(*)* +739,Thiolactams,"[#6R][CX3R](=[SX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=S +740,Imidothioesters,"[#1,#6][CX3](=[NX2][#1,#6])[SX2][C&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)SC +741,Oxohetarenes,"[$(c(=[OX1])[$(n[#1,#6]),o,s]),$(c(=[OX1])a[$(n[#1,#6]),o,s]),$(c(=[OX1])aa[$(n[#1,#6]),o,s]),$(c(=[OX1])aaa[$(n[#1,#6]),o,s])]",* +742,Thioxohetarenes,"[$(c(=[SX1])[$(n[#1,#6]),o,s]),$(c(=[SX1])a[$(n[#1,#6]),o,s]),$(c(=[SX1])aa[$(n[#1,#6]),o,s]),$(c(=[SX1])aaa[$(n[#1,#6]),o,s])]",* +743,Iminohetarenes,"[$(c(=N)[$(n[#1,#6]),o,s]),$(c(=N)a[$(n[#1,#6]),o,s]),$(c(=N)aa[$(n[#1,#6]),o,s]),$(c(=N)aaa[$(n[#1,#6]),o,s])]",* +744,Orthocarboxylic acid derivatives,"[CX4&!$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]))]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])([!#1!#6])([!#1!#6])[!#1!#6]",*C(*)(*)* +745,Carboxylic acid orthoesters,"[#1,#6][CX4]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*C(OC)(OC)OC +746,Carboxylic acid amide acetals,"[CH1,$([CX4][#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[NX3]([#1,*])[#1,*]",*N(*)*(OC)OC +747,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O +748,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O +749,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O +750,CO2 derivative (general),"[$([Cv4X4]([!#1!#6])([!#1!#6])([!#1!#6])[!#1!#6]),$([CX3](=[!#1!#6])([!#1!#6])[!#1!#6]),$([CX2](=[!#1!#6])=[!#1!#6]),$([CX2](#[!#1!#6])[!#1!#6])]",* +751,Carbonic acid derivatives,"[$([CX3](=[OX1])([!#1!#6])[!#1!#6])&!$([CX3](=[OX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +752,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH] +753,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC +754,Carbonic acid ester halides,"[#6][OX2][CX3](=[OX1])[F,Cl,Br,I]",*C(=O)OC +755,Thiocarbonic acid derivatives,"[$([CX3](=[SX1])([!#1!#6])[!#1!#6])&!$([CX3](=[SX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5]),$([CX3](=[OX1])([!#1!#6])[SX2])&!$([CX3](=[OX1])([#7,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +756,Thiocarbonic acid monoesters,"[$([OH1,SH1][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([OH1][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([SH1][CX3](=[SX1,OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +757,Thiocarbonic acid diesters,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +758,Thiocarbonic acid ester halides,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[F,Cl,Br,I]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[F,Cl,Br,I])]",* +759,Carbamic acid derivatives,"[NX3]([#1,*])([#1,*])[CX3](=[OX1])[!#1!#6!#16!$([Pv5])]",*C(=O)N(*)* +760,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH] +761,Carbamic acid esters (urethanes),"[#6][OX2][CX3](=[OX1])[NH2,NH1,NX3]",*C(=O)OC +762,Carbamic acid halides,"[F,Cl,Br,I][CX3](=[OX1])[NX3]",*C(N)=O +763,Thiocarbamic acid derivatives,"[$([NX3&!$([NX3]([CX3]=[SX1])[CX3]=[OX1,SX1,NX2])][CX3](=[SX1])[!#1!#6!#7!$([Pv5])]),$([NX3&!$([NX3]([CX3]=[OX1])[CX3]=[OX1,SX1,NX2])][CX3](=[OX1])[SH1,SX2])]",* +764,Thiocarbamic acids,"[$([OH1,SH1][CX3](=[SX1])[NX3]),$([SH1][CX3](=[OX1])[NX3])]",* +765,Thiocarbamic acid esters,"[$([#6][OX2,SX2][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])]),$([#6][SX2][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])])]",* +766,Thiocarbamic acid halides,"[F,Cl,Br,I][CX3](=[SX1])[NX3]",*C(N)=S +767,Isoureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([OX2])=[NX2][#1,#6]",*N=C(O)N(*)* +768,Isothioureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([S&!$([SX2]([CX3]=N)C=C)])=[NX2][#1,#6]",*N=C(S)N(*)* +769,Guanidines,"N[CX3](=[NX2][#1,#6])N",*N=C(N)N +770,Semicarbazides,"[$([NX3][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[OX1])[NX3]N=C)]",* +771,Thiosemicarbazides,"[$([NX3][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[SX1])[NX3]N=C)]",* +772,Isonitriles,"[#6&!$([CX3]=[OX1,SX1])][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +773,Sulfuric acid derivatives,[!#1!#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(*)(=O)=O +774,Sulfuric acid,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])[OX2,O-]",*S(*)(=O)=O +775,Sulfuric acid monoesters,"[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(=O)(=O)OC +776,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC +777,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O +778,Sulfuric acid amides,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])N",*S(N)(=O)=O +779,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O +780,Sulfuryl halides,"[!#1!#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +781,Sulfonic acid derivatives,[#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(C)(=O)=O +782,Sulfonic acids,"[#6][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(C)(=O)=O +783,Sulfonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +784,Sulfones,"[#6][Sv6X4](=[OX1,SX1,NX2])(=[OX1,SX1,NX2])[#6]",*=S(=*)(C)C +785,Sulfinic acid derivatives,[#6][Sv4X3](=[OX1])[!#1!#6],*S(C)=O +786,Sulfinic acids,"[#6][Sv4X3](=[OX1])[OH1,O-]",*S(C)=O +787,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O +788,Sulfinic acid halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +789,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O +790,Sulfenic acid derivatives,[#6][Sv2X2][!#6!#1!S],*SC +791,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH] +792,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC +793,Sulfenic acid halides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][F,Cl,Br,I]",*SC +794,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C +795,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH] +796,Thiophenols,c[Sv2H1],c[SH] +797,Phosphoric acid derivatives,"[OX1]=[Pv5X4]([H,!#6!$([SX2])])([H,!#6!$([SX2])])[H,!#6!$([SX2])]",*P(*)(*)=O +798,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH] +799,Phosphoric acid esters,[OX1]=[Pv5X4]([OX2][#6])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(=O)OC +800,Phosphoric acid halides,"[OX1]=[Pv5X4]([F,Cl,Br,I])([!#6!$([SX2])])[!#6!$([SX2])]",*P(*)(*)=O +801,Phosphoric acid amides,[OX1]=[Pv5X4]([NX3])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(N)=O +802,Thiophosphoric acid derivatives,"[$([SX1]=[Pv5X4]([H,!#6])([H,!#6])[H,!#6]),$([OX1]=[Pv5X4]([SX2])([H,!#6])[H,!#6])]",* +803,Thiophosphoric acids,"[$([SX1]=[Pv5X4]([OH1,SH1])([O,S])[O,S]),$([OX1]=[Pv5X4]([SH1])([O,S])[O,S])]",* +804,Thiophosphoric acid esters,"[$([SX1]=[Pv5X4]([OX2,SX2][#6])([!#6])[!#6]),$([OX1]=[Pv5X4]([SX2][#6])([!#6])[!#6])]",* +805,Thiophosphoric acid halides,"[$([SX1]=[Pv5X4]([F,Cl,Br,I])([!#6])[!#6]),$([OX1]=[Pv5X4]([F,Cl,Br,I])([SX2,SH1])[!#6])]",* +806,Thiophosphoric acid amides,"[$([SX1]=[Pv5X4]([NX3])([!#6])[!#6]),$([OX1]=[Pv5X4]([NX3])([SX2,SH1])[!#6])]",* +807,Phosphonic acid derivatives,[OX1]=[Pv5X4]([#6])([!#6])[!#6],*P(*)(C)=O +808,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH] +809,Phosphonic acid esters,[OX1]=[Pv5X4]([#6])([OX2][#6])[!#6],*P(C)(=O)OC +810,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C +811,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O +812,Boronic acid derivatives,[Bv3X3]([#6])([!#6])[!#6],*B(*)C +813,Boronic acids,"[BX3]([#6])([OH1,SH1])[O,S]",*B(*)C +814,Boronic acid esters,"[BX3]([#6])([OX2][#6])[H,!#6]",*B(C)OC +815,Aromatic compounds,[a!r0],* +816,Heterocyclic compounds,[*R]~[*R&!#6]~[*R],*~*~* +817,Aromatic heterocyclic compounds,[a!#6!r0],* +818,α-Aminoacids,"[OH1][CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([#6])[#6])&!$([NH1](CC(=O)[OH1])[CX3]=[OX1,SX1])]",*C(*)(*)C(=O)[OH] +819,α-Hydroxyacids,"[OH1][CX3](=[OX1])[CX4]([OH1])[#1,#6]",*C([OH])C(=O)[OH] +820,"1,2-Diamines","[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])[CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CCN(*)* +821,"1,2-Dithiols","[CX4]([SH1])([#1,#6])([#1,#6])[CX4]([SH1])([#1,#6])([#1,#6])",*C(*)([SH])C(*)(*)[SH] +822,"1,2-Aminothiols","[SH1][CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CC[SH] +823,α-Oxoacids,"[OH1][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(=O)[OH] +824,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH] +825,Dithiophenols,"[$(c([SH1])c([SH1])),$(c([SH1])[aR1]c([SH1])),$(c1([SH1])aac([SH1])aa1)]",* +826,Aminothiophenols,"[$(c([SH1])c[NX3]([#1,#6])[#1,#6]),$(c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]),$(c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1)]",* +827,Aryl halides,"a[F,Cl,Br,I]",** +828,Primary amines,"[NX3H2][c,CX4&!$([CX4]([NH2])[O,N,S,P])]",*[NH2] +829,Secondary amines,"[NX3H1]([c,CX4&!$([CX4]([NX3H1])[O,S,N,P])])[c,CX4&!$([CX4]([NX3H1])[O,S,N,P])]",*[NH]* +830,Tertiary amines,"[NX3]([c,CX4&!$([CX4]([NX3])[O,S,N,P])])([c,CX4&!$([CX4]([NX3])[O,S,N,P])])[c,CX4&!$([CX4]([NX3])[O,S,N,P])]",*N(*)* +831,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C +832,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C +833,Alkynyl halides,"[F,Cl,Br,I][CX2]#[CX2]",*C#C +834,Benzyl halides,"a[CX4][F,Cl,Br,I]",*C* +835,Benzyl fluorides,a[CX4]F,*CF +836,Benzyl chlorides,a[CX4]Cl,*CCl +837,Benzyl bromides,a[CX4]Br,*CBr +838,Benzyl iodides,a[CX4]I,*CI +839,Alkali metals,"[#3,#11,#19,#37,#55,#87]",* +840,Alkaline earth metals,"[#4,#12,#20,#38,#56,#88]",* +841,Transition metals,"[#21,#22,#23,#24,#25,#26,#27,#28,#29,#30,#39,#40,#41,#42,#43,#44,#45,#46,#47,#48,#72,#73,#74,#75,#76,#77,#78,#79,#80,#104,#105,#106,#107,#108,#109,#110,#111,#112]",* +842,Lanthanoids,"[#57,#58,#59,#60,#61,#62,#63,#64,#65,#66,#67,#68,#69,#70,#71]",* +843,Actinoids,"[#89,#90,#91,#92,#93,#94,#95,#96,#97,#98,#99,#100,#101,#102,#103]",* +844,Post-transition metals,"[#13,#31,#49,#50,#81,#82,#83,#113,#114,#115,#116]",* +845,Metalloids,"[#5,#14,#32,#33,#51,#52,#84]",* +846,Nonmetals,"[#1,#6,#7,#8,#15,#16,#34,#9,#17,#35,#53,#85,#117,#2,#10,#18,#36,#54,#86,#118]",* +847,Halogens,"[#9,#17,#35,#53,#85,#117]",* +848,Noble gases,"[#2,#10,#18,#36,#54,#86,#118]",* +849,Chalcogens (oxygen group),"[#8,#16,#34,#52,#84,#116]",* +850,Pnictogens (nitrogen group),"[#7,#15,#33,#51,#83]",* +851,Tetragens (carbon group),"[#6,#14,#32,#50,#8,#114]",* +852,Thioenolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([SX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]",*C(*)=C(*)SC +853,Thioenols,"[CX3]([#1,#6])([#1,#6])=[CX3]([SH1])[#1,#6]",*C(*)=C(*)[SH] +854,Enethiodiols,"[CX3]([#1,#6])([SH1])=[CX3]([#1,#6])([SH1])",*C([SH])=C(*)[SH] +855,Alkynyl alcohols,[CX2]#[CX2][OH1],C#C[OH] +856,Alkynyl thiols,[CX2]#[CX2][SH1],C#C[SH] +857,Thioquinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[SX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1,SX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]",* +858,4halo_pyrimidine_2_6EWG,"n1c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[n;R1]c([F,Cl,Br,I])cc1([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])",*c1cc(*)nc(*)n1 +859,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O,NC(COP(O)(O)=O)C(O)=O +860,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O,CC(OP(O)(O)=O)C(N)C(O)=O +861,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O +862,sulphonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O +863,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S,O=C(S)C(F)(F)F +864,2halo_pyrazine_5EWG,"[n;R1]1c([F,Cl,Br,I])[c;!$(c-N)]nc([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[c;!$(c-N)]1",*c1cnc(*)cn1 +865,activated_4mem_ring,"[#6]1~[$(C(=O)),$(S(=O))]~[O,S,N]~[$(C(=O)),$(S(=O))]1",*1~*~C*~1 +866,halo_5heterocycle_bis_EWG,"[n,o,s]1c([$(S(=O)(=O)),$([F,Cl]),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])c([$(S(=O)(=O)),$([F,Cl]),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])nc1([Cl,Br,I])",*c1*c(*)c(*)n1 +867,hydroxamate_warhead,C([N;H1]([O;D1]))=O,ONC=O +868,thiol_warhead,NC(C[S;D1])C(O)=O,NC(CS)C(O)=O +869,activated_vinyl_sulfonate,"O(-S(=O)(=O))C=[$(C(S(=O)(=O))),$(C(C(F)(F)(F))),$(C(C#N)),$(C(N(=O)(=O))),$(C([N+](=O)[O-])),$(C(C(=O)));!$(C(N))]",*=CO[SH](=O)=O +870,acyl_cyanide,C(=O)-C#N,N#CC=O +871,pentafluorophenylester,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +872,vinyl_carbonyl_EWG,"[C;!R]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])=[C;!R]([C;!R](=O))([!$([#8]);!$([#7])])",*C(*)=C(*)C=O 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+1102,Anisol_B,"[CH2,CH3](c4c([cH][cH]c([cH]4)[CH2][N!H0][CX4])O[CH2,CH3])",*Oc1[cH][cH]c([CH2]NC)[cH]c1* +1103,Anthranil_acid_B,"c3cc(C(=[OX1])[N!H0]c4ccccc4C(=[OX1])[OH1])cc1c3C(=[OX1])N([CH2,CH3])C1=[OX1]",*N1C(=O)c2ccc(C(=O)Nc3ccccc3C(=O)[OH])cc2C1=O +1104,Anthranil_acid_C,"[#6]1(=,:[#6]([NH2])-,:[#7](-c7ccccc7C(=[OX1])[OH1])-,:[#7]=,:[#6]1C=[OX1])[$(C#[NX1]),$(C=S)]",*C1=C([NH2])N(c2ccccc2C(=O)[OH])N=C1C=O +1105,Anthranil_acid_D,"c12ncccc1-,:[#6]([NH2])=,:[#6](C(=[OX1])~[OX1,O-])-,:[#16]2",*~C(=O)C1=C([NH2])c2cccnc2S1 +1106,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH] +1107,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH] +1108,Anthranil_acid_G,"c1([cH][cH]c(O[CH2,CH3])[cH]c1(C(=[OX1])[OH1]))[N!H0]cc",*Oc1[cH][cH]c(Ncc)c(C(=O)[OH])[cH]1 +1109,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1 +1110,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1 +1111,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH] +1112,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1 +1113,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1 +1114,Anil_alk_A,"[CH2,CH3]Occ[CH2][N!H0]c1[cH]c2n[cH]n([#6!H0])c2[cH][cH]1",*Occ[CH2]Nc1[cH][cH]c2c([cH]1)n[cH]n2C +1115,Anil_alk_B,"[N!H0](c1[cH][cH]c([CH2,CH3])[cH][cH]1)[CH2][CH2]c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c([CH2][CH2]Nc2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1116,Anil_alk_C,"[N!H0](c1ccccc1)C([#6])([#6])c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c(C(C)(C)Nc2ccccc2)[cH][cH]1 +1117,Anil_alk_D,"[N!H0](c1[cH][cH]c([C!H0]([CH2,CH3])[CH2,CH3])[cH][cH]1)[CH2][CH2]N([CH2,CH3])[CH2,CH3]",*C(*)c1[cH][cH]c(N[CH2][CH2]N(*)*)[cH][cH]1 +1118,Anil_alk_thio,c1ccc2c(c1)C3=C(C([#6])([#6])N2)SSC3=*,*=C1SSC2=C1c1ccccc1NC2(C)C +1119,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2 +1120,Anil_di_alk_F,"c1c(ccc(N([H,CX4])([H,CX4]))c1)[CX4]c2ccc(cc2)N([H,CX4])([H,CX4])",*N(*)c1ccc(Cc2ccc(N(*)*)cc2)cc1 +1121,Anil_di_alk_J,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6!H0]=[#7][#7]=[#6]([#6])-cc)[cH][cH]1",*N(*)c1[cH][cH]c(C=NN=C(C)cc)[cH][cH]1 +1122,Anil_di_alk_I,"[cH]1c([N!H0]C(=[OX1])c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=O)c2ccccc2)[cH]1 +1123,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1 +1124,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12 +1125,Anil_di_alk_ene_B,"[CH2,CH3]N([CH2,CH3])C1=Cc2ccccc2[CH2]1",*N(*)C1=Cc2ccccc2[CH2]1 +1126,Anil_di_alk_furan_B,"[CH2,CH3]N([CH2,CH3])c1[cH][cH]c(o1)[C!H0]=CC#[NX1]",*N(*)c1[cH][cH]c(C=CC#N)o1 +1127,Anil_di_alk_indol,"c12[cH][cH]c(N([CH2,CH3])[CH2,CH3])[cH]c1-,:[#6](S(=[OX1])=[OX1])=,:[#6H]-,:[#7!H0]2",*N(*)c1[cH][cH]c2c([cH]1)C(S(=O)=O)=[CH]N2 +1128,Anil_no_alk_indol_A,"c12[cH][cH]c([NH2])[cH]c1[cH][cH]n2[CH2,CH3]",*n1[cH][cH]c2[cH]c([NH2])[cH][cH]c21 +1129,Anil_NH_alk_A,"c1([N!H0][CH2,CH3])[cH][cH]c2c([cH]1)[#7!H0]-,:[#6](=[OX1])-,:[#7!H0]2",*Nc1[cH][cH]c2c([cH]1)NC(=O)N2 +1130,Anil_NH_alk_B,[N!H0](c1ccacc1)c2ccc([N!H0][C!H0])cc2,CNc1ccc(Nc2cc*cc2)cc1 +1131,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC +1132,Anil_NH_alk_D,"[NH2]c1c([N!H0][C!H0]([#6])[C!H0][CH2,CH3])c[cH][cH][cH]1",*CC(C)Nc1c[cH][cH][cH]c1[NH2] +1133,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1 +1134,Anil_NH_no_alk_B,"[NH2]c1c([N!H0]S(=[OX1])=[OX1])[cH]c([N!H0][CH2,CH3])c([F,Cl,Br,I])[cH]1",*Nc1[cH]c(NS(=O)=O)c([NH2])[cH]c1* +1135,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1 +1136,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH] +1137,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12 +1138,Anil_OC_alk_A,"[cH]1[cH][cH]c2c([cH]1)c3c(o2)[cH]c([N!H0][CH2,CH3])c(O[CH2,CH3])[cH]3",*Nc1[cH]c2oc3[cH][cH][cH][cH]c3c2[cH]c1O* +1139,Anil_OC_alk_B,"c2ccccc2N1C(=[OX1])C([N!H0]c2ccc(O[CH2,CH3])cc2)=C([F,Cl,Br,I])C1=[OX1]",*Oc1ccc(NC2=C(*)C(=O)N(c3ccccc3)C2=O)cc1 +1140,Anil_OC_alk_C,"[H,CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2]c2nccn2",*Oc1[cH][cH][cH][cH]c1N[CH2]c1nccn1 +1141,Anil_OC_alk_D,"[CH2,CH3]Oc1[cH][cH]c([CH2,CH3])[cH]c1[NH][CH2]c2c([CH2,CH3,$(O[CH2,CH3])])cccc2",*Oc1[cH][cH]c(*)[cH]c1[NH][CH2]c1ccccc1* +1142,Anil_OC_alk_E,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2][C!H0]([OH1])[CH2,CH3]",*Oc1[cH][cH][cH][cH]c1N[CH2]C(*)[OH] +1143,Anil_OC_alk_F,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][C!H0]([#16])C=[OX1]",*Oc1[cH][cH][cH][cH]c1NC(S)C=O +1144,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1 +1145,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2] +1146,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1 +1147,Anil_no_alk_B,"[NH2]c1c(n2cccc2)[cH]c([CH2,CH3])c([CH2,CH3])[cH]1",*c1[cH]c([NH2])c(n2cccc2)[cH]c1* +1148,Anil_no_alk_D,"n1c([NH2])c([CH2,CH3])[cH]c([CH2,CH3])c1[NH2]",*c1[cH]c(*)c([NH2])nc1[NH2] +1149,Anil_no_alk_C,"[NH2]c1[cH][cH]c([cH][cH]1)-c2[cH]c(C=[OX1])c([CH2,CH3])o2",*c1oc(-c2[cH][cH]c([NH2])[cH][cH]2)[cH]c1C=O +1150,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12 +1151,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1 +1152,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12 +1153,Hzone_acyl_misc_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C(=[OX1])[N!H0]N=C([H,CH2,CH3])c2cc(*-*-*c3occc3)ccc2",*C(=NNC(=O)c1[cH][cH]c(*)o1)c1cccc(***c2ccco2)c1 +1154,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1 +1155,Hzone_thiophene_A,"[cH]2[cH][cH][cH]c1c2c([C!H0]=N[N!H0]([$(c3nc[cH]s3),$(c[cH][cH]),$(cncncn),$(cnnnn)]))c([H,$([OH1]),CH2,CH3])[a!c]1",*NN=Cc1c(*)*c2[cH][cH][cH][cH]c12 +1156,Hzone_thiophene_B,"c1(s[cH][cH]c1[H,CH2,CH3])[C!H0]=N[N!H0]c2ccccc2",*c1[cH][cH]sc1C=NNc1ccccc1 +1157,Hzone_phenone,"C(c1[cH]cc([H,CX4])[cH][cH]1)(c2[cH][cH]c([H,Cl])[cH][cH]2)=[$(NO[CH2][CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(NO[CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(N[N!H0]C(=[NH1])[NH2]),$([#6!H0][#7])]",*c1c[cH]c(C(=*)c2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1158,Hzone_furan_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[N!H0]c2nccs2",*C(=NNc1nccs1)c1[cH][cH]c(*)o1 +1159,Hzone_furan_B,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[NH]c2ccncc2",*C(=N[NH]c1ccncc1)c1[cH][cH]c(*)o1 +1160,Hzone_furan_C,c1ccccc1N(c2ccccc2)N=[C!H0]c3ac([cH][cH]3)-c4cc(C(=[OX1])[OH1])ccc4,O=C([OH])c1cccc(-c2*c(C=NN(c3ccccc3)c3ccccc3)[cH][cH]2)c1 +1161,Hzone_furan_E,[OH1]C(=[OX1])c1cc(ccc1)-cacC=N[N!H0]C(=[OX1])[CH2][#8],O[CH2]C(=O)NN=Cc*c-c1cccc(C(=O)[OH])c1 +1162,Hzone_naphth_A,"[cH]1[cH][cH]c2[cH][cH]c(C=N[N!H0][$(cc),$(C=[SX1])])[cH]c2c1",*NN=Cc1[cH][cH]c2[cH][cH][cH]cc2[cH]1 +1163,Hzone_acid_A,"[cH]1[cH]c(O[CH2,CH3])[cH]c2C(=N[N!H0]c4[cH][cH]c(C(=[OX1])[OH1])[cH][cH]4)c3[cH]c(O[CH2,CH3])[cH][cH]c3c12",*Oc1[cH][cH]c2c([cH]1)C(=NNc1[cH][cH]c(C(=O)[OH])[cH][cH]1)c1[cH]c(O*)[cH][cH]c12 +1164,Hzone_acid_D,[OH1]C(=[OX1])c1ccc(cc1)NN=[C!H0]c2ac([cH][cH]2)-c3ccccc3,O=C([OH])c1ccc(NN=Cc2*c(-c3ccccc3)[cH][cH]2)cc1 +1165,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1 +1166,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1 +1167,Het_5_C,"N1=C(c2ccccc2)[CH2]C([OH1])([CX4](F)(F)F)N1[$(cccccc),$(C(=S)cccccc)]",*N1N=C(c2ccccc2)[CH2]C1([OH])C(F)(F)F +1168,Het_5_D,"N1(c2ccccc2)N=C([CH2,CH3])[C!H0](S[#6])C1=[OX1]",*C1=NN(c2ccccc2)C(=O)C1SC +1169,Het_5_E,"N1(c2cccc3ccccc23)N=C([CH2,CH3])[CH2]C1=[OX1]",*C1=NN(c2cccc3ccccc23)C(=O)[CH2]1 +1170,Het_5_ene,"C1(=[OX1])C(=C([CH2,CH3])[N!H0][CH2][CH2][CH2,CH3])N=C(c2ccccc2)O1",*[CH2][CH2]NC(*)=C1N=C(c2ccccc2)OC1=O +1171,Het_5_inium,"[#7]1(c2ccccc2)[#6!H0]=[#7+,#7v4](c3ccccc3)[#6](=Nc4ccccc4)N1",C1=*(c2ccccc2)C(=Nc2ccccc2)NN1c1ccccc1 +1172,Het_5_pyrazole_OH,"n1(c2[cH][cH][cH][cH][cH]2)nc([CX4])c([H,C!H0])c1[OH1]",*c1c(C)nn(c2[cH][cH][cH][cH][cH]2)c1[OH] +1173,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1 +1174,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1 +1175,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1 +1176,Het_6_pyridone_NH2,[OH1]c2nc([NH2])acc2[CH2]C(=[OX1])[#8],[NH2]c1*cc([CH2]C(O)=O)c([OH])n1 +1177,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1 +1178,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2 +1179,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1 +1180,Het_65_B,a1a3a(aaa1)[N!H0]N(C3=O)[#6],CN1N*2:*:*:*:*:*:2C1=O +1181,Het_65_C,"C1=CC=CC2=NC([$(C([!#1])=[C!H0]cc),$(coc)])=C(Ncc)N12",*C1=C(Ncc)N2C=CC=CC2=N1 +1182,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1183,Het_65_F,"[#16]1-,:[#6]2:[#6](-,:[#6]([CH2,CH3])=,:[#6]1[CH2,CH3])c(ncn2)NN=C[#6]3=,:[#6]-,:[#6]=,:[#6]-,:[#8]3",*C1=C(*)C2:C(ncnc2NN=CC2=CC=CO2)S1 +1184,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1 +1185,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1 +1186,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12 +1187,Het_65_J,"o1c([#6](~[#8])~[#8])cc2[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c12",*Oc1[cH]c2cc(C(~O)~O)oc2[cH]c1O* +1188,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1 +1189,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O +1190,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12 +1191,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21 +1192,Het_65_pyridone_A,"c1([CH2][CH2,CH3])c([CH2,CH3])c2C(=[!#1!#6X1])N([C!H0][$(C(=O)O),$(cc)])C([H,$(S(C)[CH2,CH3])])=Nc2[a&!c;X2]1",*CN1C(=*)c2c(*c([CH2]*)c2*)N=C1* +1193,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1 +1194,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1 +1195,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1 +1196,Het_66_B,"c1ccc4c(c1)nc(nc4)[N!H0]C2=NC(C=C[N!H0]2)([CH2,CH3])[CH2,CH3]",*C1(*)C=CNC(Nc2ncc3ccccc3n2)=N1 +1197,Het_66_C,c1ccc2nc([C!H0]=C([OH1])[#6])c([C!H0]=C([OH1])[#6])nc2a1,CC([OH])=Cc1nc2*cccc2nc1C=C(C)[OH] +1198,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc +1199,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1 +1200,Het_66_anisole,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0]c2c3c(O[CH2,CH3])ccc(O[CH2,CH3])c3ncc2",*Oc1[cH][cH][cH][cH]c1Nc1ccnc2c(O*)ccc(O*)c12 +1201,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1 +1202,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3 +1203,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21 +1204,Het_565_indole,"[#6!H0]1=,:[#6!H0]-,:[#7]([CH2,CH3])c7c1c9[#6!H0]=,:[#6!H0]-,:[#7](c9c(c7O[CH2,CH3])O[CH2,CH3])[CH2,CH3]",*Oc1c(O*)c2c(c3c1N(*)C=C3)C=CN2* +1205,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21 +1206,Het_666_B,"c1cccc9c1Oc2c(N9[CH2][CH2,CH3])cccc2",*[CH2]N1c2ccccc2Oc2ccccc21 +1207,Het_666_C,"c13cc2ccccc2cc1-,:[#7]([CH2,CH3])-,:[#6](=[OX1])-,:[#6](-cc[N!H0][CH2,CH3])=,:[#7]3",*NccC1=Nc2cc3ccccc3cc2N(*)C1=O +1208,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12 +1209,Het_pyridiniums_B,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:*2=,:[#6]1-,:*=,:[#7+,#7v4](~cc)-,:*=,:[#6]2[H,*]",*C1=**(~cc)=*C2=*1C=CC=C2 +1210,Het_pyridiniums_C,"[#6]1~[#6]~[#6]~[#7+,#7v4]2~[#6](~[#7]1)~[#6]3~[#6]~[#6]~[#6]~[#7](-cc)~[#6]3~[#7]2",ccN1~C~C~C~C2C~1~N*1~C~C~CN~C~1~2 +1211,Het_thio_5_A,"[CH2,CH3][SX2]c1n(-!@[CH2,CH3])c(-c2ccccc2)[cH]n1",*Sc1n[cH]c(-c2ccccc2)n1* +1212,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1 +1213,Het_thio_5_C,"[SX1]=[#6]1-,:[#7!H0]-,:[#7]=,:[#6](c2[cH][cH]c(O[CH2,CH3])[cH][cH]2)-,:[#8]1",*Oc1[cH][cH]c(C2=NNC(=S)O2)[cH][cH]1 +1214,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1 +1215,Het_thio_5_imine_B,"N1([CH2,CH3])C(=S)N(-cc)C(=N-cc)C1=N-cc",*N1C(=S)N(cc)C(=Ncc)C1=Ncc +1216,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc +1217,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1 +1218,Het_thio_6_furan,"[CH2,CH3][SX2]c1nc(-c2o[cH][cH][cH]2)c(-c3o[cH][cH][cH]3)nn1",*Sc1nnc(-c2[cH][cH][cH]o2)c(-c2[cH][cH][cH]o2)n1 +1219,Het_thio_65_A,"[#7]1=,:[#6]([SX2][CH2,CH3])-,:[#7]=,:[#7]-,:[#6]2=,:[#6]1-,:[#6]([CH2,CH3])=,:[#7]-,:[#7]2-c3cccccc3",*SC1=NC2=C(N=N1)N(c1cccccc1)N=C2* +1220,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1 +1221,Het_thio_65_C,"n1c2ccccc2n([CH2,CH3])c1S[CH2]C(=[OX1])[N!H0]N=[C!H0][C!H0]=[C!H0]",*n1c(S[CH2]C(=O)NN=CC=C)nc2ccccc21 +1222,Het_thio_65_D,"c1(S[CH2]C(=[OX1])[NH]-cc)nc2[cH]c([F,Cl,Br,I])c[cH]c2[nH]1",*c1c[cH]c2[nH]c(S[CH2]C(=O)[NH]cc)nc2[cH]1 +1223,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1 +1224,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1 +1225,Het_thio_67_A,"[CH2,CH3][SX2]c1nc2OC=Ncc-c2nn1",*Sc1nnc2c(n1)OC=Ncc-2 +1226,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21 +1227,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12 +1228,Het_thio_656c,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]2-,:[#7+,#7v4]=,:[#6]3-,:[#7](N=C(c5ccccc5)[CX4]S3)-,:[#6]12",*1=C2SCC(c3ccccc3)=NN2C2C=CC=CC12 +1229,Het_thio_665,"c1ccc7c(c1)NC3=C(S7)SC(=C3)[CH2,CH3]",*C1=CC2=C(S1)Sc1ccccc1N2 +1230,Het_thio_666_A,"[cH]1[cH][cH][cH]c5N([H,CH3,$([CH2][C!H0])])c7c(~[H,$([N!H0][CX4]),$(cc)])c(~[H,$(cc)])c([H,NH2,$([OX2][CX4])])[cH]c7Sc15",*~c1c(~*)c2c([cH]c1*)Sc1[cH][cH][cH][cH]c1N2* +1231,Het_thio_676_A,"c1ccc4c(c1)Sc8[cH][cH]c([cH]c8C(C4)N([H,CX4])([H,CX4]))[H,#8,#16X2,CX4,$(N([H,CX4])[H,CX4])]",*c1[cH][cH]c2c([cH]1)C(N(*)*)Cc1ccccc1S2 +1232,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21 +1233,Het_thio_pyr_A,"n1c(S[C!H0])c(C#[NX1])c(c2ccc(O[Ch2,CH3])cc2)[cH]c1(cc)",*Oc1ccc(c2[cH]c(cc)nc(SC)c2C#N)cc1 +1234,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1 +1235,Het_thio_N_5B,"[#6]1~[#6](~[#7]~[#7]~[#6](~[CH2,CH3])~[CH2,CH3])~[#7]~[#16]~[#6]1",*~C(~*)~N~N~C1~CC~S~N~1 +1236,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1 +1237,Het_thio_N_55,[C!H0]c1nn(c3ccccc3)s2[a!c]acc12,Cc1nn(c2ccccc2)s2*:*cc12 +1238,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2 +1239,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc +1240,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1 +1241,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21 +1242,Styrene_B,"c1ccc4c(c1)[SX2,CX4]c8ccc(cc8C4=CC)[H,Cl,CX4]",*c1ccc2c(c1)C(=CC)c1ccccc1*2 +1243,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2 +1244,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21 +1245,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc +1246,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21 +1247,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN +1248,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S +1249,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N +1250,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1 +1251,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1 +1252,Ene_five_het_G,"C1(=[OX1])C(=[C!H0][$(c2ccccc2),$(c2ccc[a!c]2)])N=C(aaa)[#16,$(Naa)]1",*C=C1N=C(*:*:*)*C1=O +1253,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S +1254,Ene_five_het_I,c1(ccco1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2,O=C1C(=Cc2ccco2)*c2ccccc21 +1255,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S +1256,Ene_five_het_K,"[#7]1([#6])-,:[#6H]=,:[#6H]-,:[#6H]=,:[#6]1([CH]=C2C(=[OX1])[!#6]C=,:*2)",CN1[CH]=[CH][CH]=C1[CH]=C1*=C*C1=O +1257,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1 +1258,Ene_five_het_M,"C1=,:C[O,S]C(=CC=[OX1])C1=[OX1]",O=CC=C1*C=CC1=O +1259,Ene_five_het_N,"C1(=[OX1])C(=[C!H0]c2cc([F,Cl,Br,I])ccc2O[CH2,CH3])N=C(S[CH2,CH3])S1",*Oc1ccc(*)cc1C=C1N=C(S*)SC1=O +1260,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1 +1261,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O +1262,Ene_six_het_D,[OX1]=C1NNC(aa)=NC1=[C!H0],*:*C1=NC(=C)C(=O)NN1 +1263,Ene_quin_methide,"aaC([H,$(C#[NX1])])=[#6]1-,:[#6]=,:[#6]-,:[#6](=[OX1,N!R])-,:[#6]=,:[#6]1",*C(*:*)=C1C=CC(=*)C=C1 +1264,Ene_rhod_C,"S1C(=Ncc)N([H,$([CH2][CH2]O),$(cc)])C(=[OX1])C1(=[C!H0][$(cccCl),$(c[a!c])])",*C=C1SC(=Ncc)N(*)C1=O +1265,Ene_rhod_D,"S1C(=!@N[H,$([N!H0](N)cc)])N([H,$(cnccs)])C(=[OX1])C1=[C!H0]cc[Cl,$(O[C!H0])]",*ccC=C1SC(=N*)N(*)C1=O +1266,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S +1267,Ene_rhod_F,"n1ccc([C!H0]=C2C(=[OX1])NC(=[!#1!#6])N2)c1[CH2,CH3]",*c1nccc1C=C1NC(=*)NC1=O +1268,Ene_rhod_G,[OH1][CX3](=[OX1])c1cccc(c1)cac[C!H0]=C2C(=[!#1!#6])NC(=[!#1!#6])[!#1!#6]2,*=C1*C(=Cc*cc2cccc(C(=O)[OH])c2)C(=*)N1 +1269,Ene_rhod_H,"N1=C([CH2,CH3])C(=[OX1])N=C2N1C(=[OX1])C(=[C!H0]cc)S2",*C1=NN2C(=O)C(=Ccc)SC2=NC1=O +1270,Ene_rhod_I,"N1([CH2,CH3])C(=S)[N!H0]C(=[C!H0]c2cc(Br)ccc2)C1(=O)",*N1C(=O)C(=Cc2cccc(Br)c2)NC1=S +1271,Ene_rhod_J,"[CH2,CH3]N1C(=[#16,#7])[!#6]C(=[#6]2-,:[#6H]=,:[#6H]cc-,:[#7]2[CH2,CH3])C1=[OX1]",*N1cc[CH]=[CH]C1=C1*C(=*)N(*)C1=O +1272,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1 +1273,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O +1274,Ene_misc_C,"c1ccc4c(c1)N(C(C=C4)([CH2,CH3])[CH2,CH3])C(=[OX1])[N!H0]c3ccc(c(c3)O[CH2,CH3])O[CH2,CH3]",*Oc1ccc(NC(=O)N2c3ccccc3C=CC2(*)*)cc1O* +1275,Ene_misc_D,"c12[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c1C([#6])=C([#6])S[CH2]2",*Oc1[cH]c2c([cH]c1O*)C(C)=C(C)S[CH2]2 +1276,Ene_misc_E,"c1(O[CH2,CH3])c(O[CH2,CH3])[cH]c2C=C[C!H0]Sc2[cH]1",*Oc1[cH]c2c([cH]c1O*)SCC=C2 +1277,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1 +1278,Dhp_amino_CN_A,"[NH2]C1=C(C#[NX1])[C!H0](cc)C([CH2,CH3])=C(C=C)O1",*C1=C(C=C)OC([NH2])=C(C#N)C1cc +1279,Dhp_amino_CN_B,"[NX3H2,OX2H1]C1=C(C#[NX1])[C!H0](cc)c2c(n(C)nc2)O1",*C1=C(C#N)C(cc)c2cnn(C)c2O1 +1280,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N +1281,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21 +1282,Dhp_amino_CN_E,"[CH2,CH3][SX2]C1=C(C#[NX1])[C!H0](cc)C(C#[NX1])C(=O)N1",*SC1=C(C#N)C(cc)C(C#N)C(=O)N1 +1283,Dhp_amino_CN_F,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](c2cccs2)-,:[#6](C(=[OX1])O[#6])=,:[#6]([CH2,CH3])-,:[#8]1",*C1=C(C(=O)OC)C(c2cccs2)C(C#N)=C([NH2])O1 +1284,Dhp_amino_CN_G,"[SX2]1C=C(C#[NX1])C([#6])(C=[OX1])C([$(C=[OX1]),$(C#[NX1])])=C1[NH2]",*C1=C([NH2])SC=C(C#N)C1(C)C=O +1285,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N +1286,Dhp_keto_A,"[#7]1([H,CX4])-,:[#6]=,:[#6](C(=[OX1])ccc)-,:[#6]([#6])-,:[#6]([$(C=[OX1]),$(C#[NX1])])=,:[#6]1[CH3]",*C1=C([CH3])N(*)C=C(C(=O)ccc)C1C +1287,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2] +1288,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1 +1289,Сyano_keto_A,"[CH2,CH3][C!H0](C#[NX1])C(=[OX1])[#6]",*C(C#N)C(C)=O +1290,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N +1291,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N +1292,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc +1293,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O +1294,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O +1295,Cyano_pyridone_C,"C1(C([CH2,CH3])=C(C#[NX1])C(~[#8])~[#7]~[#6]1(~[#8]))=[C!H0]cc",*C1=C(C#N)C(~O)~N~C(~O)C1=Ccc +1296,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O +1297,Cyano_pyridone_E,"ac[#6]1=,:[#6!H0]-,:[#6](co)=,:[#6](C#[NX1])-,:[#6](=[OX1])-,:[#7!H0]1",*cC1=CC(co)=C(C#N)C(=O)N1 +1298,Cyano_pyridone_G,"N1(c2ccc(O[CH2,CH3])cc2)C(=[OX1])C(C#[NX1])=CC(n3cncc3)=N1",*Oc1ccc(N2N=C(n3ccnc3)C=C(C#N)C2=O)cc1 +1299,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12 +1300,Thio_aldehyd_A,"[#1,#6][C!H0](=[SX1])",*C=S +1301,Thio_amide_A,"[#6!H0]1=,:[#6]-,:[#8]-,:[#6](=,:[#6!H0]1)C(=[SX1])N5[CH2][CH2]*[CH2][CH2]5",S=C(C1=CC=CO1)N1[CH2][CH2]*[CH2][CH2]1 +1302,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc +1303,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1 +1304,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C +1305,Thio_amide_E,"c1cccnc1C(=S)[N!H0]c2ccccc2O[CH2,CH3]",*Oc1ccccc1NC(=S)c1ccccn1 +1306,Thio_amide_F,acC(=S)[N!H0][N!H0]ca,*cNNC(=S)c* +1307,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1 +1308,Thio_ester_B,"ccC(=[SX1])[SX2][C!H0][CH2,CH3,$(cc)]",*CSC(=S)cc +1309,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1 +1310,Thio_ene_amine_A,"S=CC([CH2,CH3])=C([CH2,CH3])N([CH2,CH3])[CH2,CH3]",*C(C=S)=C(*)N(*)* +1311,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O +1312,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1 +1313,Thio_pyridine_A,c1(nanc(c2o[cH][cH][cH]2)n1)S[CX4],CSc1n*nc(c2[cH][cH][cH]o2)n1 +1314,Thio_thiomorph_Z,"[OX1]=C(N3CCSCC3)c9c([cH][cH][cH][cH]9)S[CH2,CH3]",*Sc1[cH][cH][cH][cH]c1C(=O)N1CCSCC1 +1315,Thio_urea_A,"c1c([N!H0][CX3](=[SX1])[N!H0][CH2][CH2][CH2]N([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1316,Thio_urea_B,"c1c([#7!H0]C(=S)[#7!H0][CH2][CH2][#7]([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1317,Thio_urea_C,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]C(=[OX1])c2a[a!c]cc2,O=C(NNC(=S)Nc1ccccc1)c1*:*cc1 +1318,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1 +1319,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1 +1320,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1 +1321,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1 +1322,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1 +1323,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1 +1324,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S +1325,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12 +1326,Thio_urea_L,[CX4][SX2]C(=N-aaaa)[N!H0]N=[#6],*:*:*:*N=C(NN=C)SC +1327,Thio_urea_M,"cc[#7]([CH2,CH3])[CH2][CH2][CH2][#7!H0]C(=S)[#7!H0]c1c([F,Cl,Br,I])[cH]c([CH2,CH3])[cH][cH]1",*c1[cH][cH]c(NC(=S)N[CH2][CH2][CH2]N(*)cc)c(*)[cH]1 +1328,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1 +1329,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1 +1330,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2 +1331,Thio_urea_Q,"[cH]1[cH][cH][cH]c2[cH][cH][cH]c(c12)C([CH2,CH3])=N[N!H0]C(=S)[N!H0]ccc",*C(=NNC(=S)Nccc)c1[cH][cH][cH]c2[cH][cH][cH][cH]c12 +1332,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1 +1333,Thio_carbam_A,"[CH2,CH3]SC(=S)[N!H0][CH2]-cc",*SC(=S)N[CH2]cc +1334,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1 +1335,Thio_carbonate_B,"[OX1]=[#6]1-,:[#16]c2cccc(O[CH2,CH3])c2-,:[#8]1",*Oc1cccc2c1OC(=O)S2 +1336,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N +1337,Thio_imine_ium,"[CX4][#7+,#7v4]([CX4][OH1])=CS[C!H0]",CSC=*(C)C[OH] +1338,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12 +1339,Thiophene_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=CC(=[OX1])c1c([SX2])sc([$(C#[NX1]),$(C=[OX1])])c1",*c1cc(C(=O)C=CN(*)*)c(S)s1 +1340,Thiophene_D,"s1[cH][cH]c(O[CH2,CH3])c1C(=[OX1])[N!H0][N!H0]",*Oc1[cH][cH]sc1C(=O)NN +1341,Thiophene_E,"c1(sc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])C(=[OX1])[NH]c2nccs2",*C(C(=O)[NH]c1nccs1)c1[cH][cH]c(*)s1 +1342,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C +1343,Thiophene_amino_B,"c2ccccc2[#7!H0]c1sc([$([#6]=[#8]),$(C#[#7]),$([#6]([#8!H0])=[#6])])c([#7])c1[$(C#[#7]),$([#6](n)n)]",*c1sc(Nc2ccccc2)c(*)c1N +1344,Thiophene_amino_C,"[C!H0][CH2]c1sc([N!H0]C(=[OX1])CCC=[OX1])c([$(C(=[OX1])O),$(C#[NX1])])c1[CH2,CH3]",*c1c([CH2]C)sc(NC(=O)CCC=O)c1* +1345,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N +1346,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1 +1347,Thiophene_amino_F,[NH2]c1sc([NH]C(=[OX1])c3ccccc3)c(C#[NX1])c1c2aaaaa2,N#Cc1c([NH]C(=O)c2ccccc2)sc([NH2])c1c1*:*:*:*:*1 +1348,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH] +1349,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc +1350,Keto_naphthol_A,"[#6]C(=[OX1])c1cccc2cccc([OH1,NH2])c12",*c1cccc2cccc(C(C)=O)c12 +1351,Keto_thiophene,"c1(sc2ccccc2c1([CH2,CH3]))C(=[OX1])[CH2][CH2,CH3]",*[CH2]C(=O)c1sc2ccccc2c1* +1352,Keto_phenone_A,c1cccc5c1C(c8c5nacc8)=[OX1],O=C1c2ccccc2c2n*ccc21 +1353,Keto_phenone_B,c1cccc5c1C(C8C5=N[!#1!#6]=CC8)=[OX1],O=C1C2CC=*N=C2c2ccccc21 +1354,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12 +1355,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1 +1356,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1 +1357,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O +1358,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH] +1359,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O +1360,Keto_keto_beta_F,"[CH2,CH3]C([OH1])=C(C(=[OX1])[CH2,CH3])[C!H0]C#C",*C(=O)C(CC#C)=C(*)[OH] +1361,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21 +1362,Thiaz_ene_C,"[#6]1([F,Cl,Br,I,$([#7v4R,#7v4R+](=,:[#6R])-,:[#6R])])=,:[#6](-!@C=N)-,:[#16]-,:[#6](=[OX1])-,:[#7]1",*C1=C(C=N)SC(=O)N1 +1363,Acyl_het_A,"[#7v4,#7+](=,:*-,:*=,:*)-,:*=O",*=**=**=O +1364,Anil_di_alk_G,"[CX4]N([CX4])c1[cH][cH]c([#6]2=,:[#7]-,:[#6]=,:[#6]-,:*2)[cH][cH]1",CN(C)c1[cH][cH]c(C2=NC=C*2)[cH][cH]1 +1365,Anil_di_alk_H,"[cH]1c([N!H0]S(=[OX1])(=[OX1])c2caccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NS(=O)(=O)c2c*ccc2)[cH]1 +1366,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1 +1367,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21 +1368,Anil_di_alk_O,"[cH]1c([N!H0]C(=S)[N!H0]c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=S)Nc2ccccc2)[cH]1 +1369,Anil_di_alk_P,"[CH2,CH3]N([CH2,CH3])c1cc2nc(S[CH2,CH3])sc2cc1",*Sc1nc2cc(N(*)*)ccc2s1 +1370,Anil_di_alk_ene_A,"[CH2,CH3]N([CH2,CH3])C1=[C!H0]c2ccccc2[SX2]c3ccccc13",*N(*)C1=Cc2ccccc2Sc2ccccc21 +1371,Anil_di_alk_dhp,"N1C=C(C=[OX1])C(-c3ccc(N([CH2,CH3])[CH2,CH3])cc3)C2=C1(~[#7]~[#6](~[#16])~[#7]~[#6]2~[#7])",*N(*)c1ccc(C2C(C=O)=CNC3=C2C(~N)~N~C(~S)~N~3)cc1 +1372,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21 +1373,Anil_di_alk_coum,"c2ccccc2N([C!H0])[C!H0][C!H0][C!H0][N!H0]C(=[OX1])[#6]1-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6](=[OX1])-,:[#8]-,:[#6]([CH2,CH3])=,:1",*C1=CC(=O)OC(*)=C1C(=O)NCCCN(C)c1ccccc1 +1374,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1 +1375,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O +1376,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O +1377,Ene_one_amide_A,"c1ccccc1[C!H0]NC(=[OX1])C([N!H0][CH2,CH3])=[C!H0]C(=[OX1])c2ccc(O[CH2,CH3])cc2",*NC(=CC(=O)c1ccc(O*)cc1)C(=O)NCc1ccccc1 +1378,Ene_one_amide_B,"c13ccc2ccccc2c1[C!H0][CX4]NC3=[C!H0]C(=[OX1])N([CH2,CH3])[CH2,CH3]",*N(*)C(=O)C=C1NCCc2c1ccc1ccccc21 +1379,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1 +1380,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O +1381,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C +1382,Imine_one_B,"[N!H0](c1ccccc1)N=C(C(=[OX1])[CH2,CH3])[N!H0][$([N!H0]),$(cc)]",*NC(=NNc1ccccc1)C(*)=O +1383,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1 +1384,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1 +1385,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21 +1386,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C +1387,Imine_imine_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=NC([CH2,CH3])=NN([CH2,CH3])cc",*C(N=CN(*)*)=NN(*)cc +1388,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O +1389,Imine_one_fives_C,cc[N!R]=C2C(=[!#1!#6])c5ccccc5N2,*=C1C(=Ncc)Nc2ccccc21 +1390,Imine_one_fives_D,C1(=[!#1!#6])C(N=CS1)=O,*=C1SC=NC1=O +1391,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH] +1392,Imine_naphthol_A,"c12c([cH][cH][cH][cH]1)c(c([cH][cH]2)C(=N-cc)[CH2,CH3])[OH1]",*C(=Ncc)c1[cH][cH]c2[cH][cH][cH][cH]c2c1[OH] +1393,Pyrrole_C,"[#7]1([CX4])-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6!H0]=,:[#6]1cc",*C1=CC=C(cc)N1C +1394,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S +1395,Pyrrole_E,"[#7]1(c2[cH]a[a!c]a2)-,:[#6]([CX4])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CX4]",CC1=CC=C(C)N1c1*:*:*[cH]1 +1396,Pyrrole_F,[cH]1[cH]n(-c2[a!c]ccc2C#[NX1])c[cH]1,N#Cc1cc*c1-n1c[cH][cH][cH]1 +1397,Pyrrole_G,"n1(c2c[cH]c([$([NH2]),$(cn)])c[cH]2)[cH][cH][cH][cH]1",*c1c[cH]c(n2[cH][cH][cH][cH]2)c[cH]1 +1398,Pyrrole_H,"C1=[Nv4,N+]([#6])CC[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]12",C*1=CC2=CC=CN2CC1 +1399,Pyrrole_I,"[#7]1([CH2,CH3])-,:[#6]2=,:[#6](-,:[#6]:[#6]-,:[#6]2=[OX1])-,:[#6]=,:[#6]1[CH2,CH3]",*C1=CC2=C(C(=O)C:C2)N1* +1400,Pyrrole_J,"[#6]1(=,:[#6]2-,:[#6](=,:[#6](-,:[#7]1C(O)=[OX1])[CH2,CH3])S[CH2]S2)[CH2,CH3]",*C1=C2S[CH2]SC2=C(*)N1C(O)=O +1401,Pyrrole_K,"[#6]1(-,:[#7!H0]-,:[#6](c2[cH][cH][cH][cH][cH]2)=,:[#6]([CH2,CH3])-,:[#6H]=,:1)C(=[OX1])[OH1]",*C1=C(c2[cH][cH][cH][cH][cH]2)NC(C(=O)[OH])=[CH]1 +1402,Pyrrole_L,"[n!H0]1c(C(=[OX1])O[CH2,CH3])c([CH2,CH3])c([CH2][CH2,CH3])c1[CH2][CH2,CH3]",*[CH2]c1nc(C(=O)O*)c(*)c1[CH2]* +1403,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1 +1404,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1 +1405,Pyrrole_O,"[#7]1([CH2,CH3])-,:[#6]([CH2,CH3])=,:[#6](C(=[OX1])[#6])-,:[#6]=,:[#6]1-cc",*C1=C(C(C)=O)C=C(cc)N1* +1406,Thiaz_ene_D,"c2ccccc2[#7][#6]1=,:[#7+,#7v4]-,:[#6](c3ccccc3)=,:[#6][#16]1",*1=C(Nc2ccccc2)SC=C1c1ccccc1 +1407,Thiaz_ene_E,"C1(S[#6R])=C([C!H0]([#6])[#6])SC(N1([H,CH2,CH3]))=[OX1]",*N1C(=O)SC(C(C)C)=C1SC +1408,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21 +1409,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O +1410,Quinone_D,"[!#1!#6]=[#6]1[#6]=,:[#6][#6]=,:[#6][#6]1=[!#1!#6]",*=C1C=CC=CC1=* +1411,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1 +1412,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1 +1413,Diazox_C,N2=Nc1n[a!c]nc1N=Ncc2,*1nc2c(n1)N=NccN=N2 +1414,Diazox_D,[C!H0]1([OH1])c2n[a!c]nc2[C!H0]([OH1])C=C1,[OH]C1C=CC([OH])c2n*nc21 +1415,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2] +1416,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1 +1417,Sulfonamide_C,[cH]1c([N!H0]S(=[OX1])(=[OX1])c2ccc([!#1!#6])cc2)[cH]c3c(O[CH2]O3)[cH]1,*c1ccc(S(=O)(=O)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)cc1 +1418,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1 +1419,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc +1420,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1 +1421,Sulfonamide_G,"[CH3]c5nc([N!H0]S(c2[cH][cH]c([cH][cH]2)O[CH2][CH2][CH2,CH3])(=[OX1])(=[OX1]))[cH][cH][cH]5",*[CH2][CH2]Oc1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]c([CH3])n2)[cH][cH]1 +1422,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1 +1423,Sulfonamide_I,"S(=[OX1])(=[OX1])(c1cn([CH2,CH3])cn1)[N!H0]c2cnn([CH2]ccO[CH2,CH3])c2",*Occ[CH2]n1cc(NS(=O)(=O)c2cn(*)cn2)cn1 +1424,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1 +1425,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc +1426,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1 +1427,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1 +1428,Thiazole_amine_B,"c1(ccc([CH2,CH3])cc1)-c2nc([NH2])sc2[CH3]",*c1ccc(-c2nc([NH2])sc2[CH3])cc1 +1429,Thiazole_amine_C,"c1([N!H0][CH2]c2[cH][cH][cH]o2)nc(aaa([$(O[CH2,CH3]),CH2,CH3])aa)[cH]s1",**(:*:*):*:*c1[cH]sc(N[CH2]c2[cH][cH][cH]o2)n1 +1430,Thiazole_amine_D,"[#16]1-,:[#6]([N!H0]c2c([CH2,CH3,$(cc)])cccc2)=,:[#7+,#7v4]([CH2,CH3])-,:[#6]([#6])=,:[#6H]1",**1=C(Nc2ccccc2*)S[CH]=C1C +1431,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O +1432,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1 +1433,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1 +1434,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1 +1435,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1 +1436,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3 +1437,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1 +1438,Thiazole_amine_M,"c1([N!H0]cc[CH2,CH3])nc(c2ccncc2)[cH]s1",*ccNc1nc(c2ccncc2)[cH]s1 +1439,Thiazole_amine_N,"[CH2,CH3]Oc1[cH][cH]c(O[CH2,CH3])[cH]c1[N!H0]c2scc(-c3ccc(O[CH2,CH3])cc3)n2",*Oc1ccc(-c2csc(Nc3[cH]c(O*)[cH][cH]c3O*)n2)cc1 +1440,Furan_acid_A,"c1(oc([CH2,CH3])c([CH2]Occ)[cH]1)[CX3](=[OX1])[OH1]",*c1oc(C(=O)[OH])[cH]c1[CH2]Occ +1441,Furan_A,"c1(oc([CH2,CH3])[cH][cH]1)[C!H0]([OH1])C#C[CX4]",*c1[cH][cH]c(C([OH])C#CC)o1 +1442,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N +1443,Colchicine_B,"[CH2,CH3]Sc1ccc(cc1)C2=CC(=[OX1])[#6]3=,:[#6]-,:[#8]-,:[#6]=,:[#6]3C([OH1])=C2",*Sc1ccc(C2=CC(=O)C3=COC=C3C([OH])=C2)cc1 +1444,Colchicine_het,"c1cccc3-,:[#7]([CH2,CH3])-,:[#6](=NN=[#6]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]2)-,:[#16]-,:c13",*N1C(=NN=C2C=CC=CC=C2)Sc2ccccc21 +1445,Rhod_sat_B,"N1(c2c([CH2,CH3])cccc2)C(=S)N([CH2]aaaaa)[CH2]C1=[OX1]",*c1ccccc1N1C(=O)[CH2]N([CH2]*:*:*:*:*)C1=S +1446,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1 +1447,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O +1448,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1 +1449,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1 +1450,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1 +1451,Melamine_A,"o1[cH][cH][cH]c1[CH2][N!H0]c1c2ccccc2nc([N!H0]c4c([H,CH2,CH3,SX2,$(O[C!H0])])cc([H,CH2,CH3,SX2,$(O[C!H0])])c([H,CH2,CH3,SX2,$(O[C!H0])])c4)n1",*c1cc(*)c(Nc2nc(N[CH2]c3[cH][cH][cH]o3)c3ccccc3n2)cc1* +1452,Melamine_B,"n1c(N([CH2,CH3])[CH2,CH3])nc(N([CH2,CH3])[CH2,CH3])nc1N([C!H0])C=[OX1]",*N(*)c1nc(N(*)*)nc(N(C)C=O)n1 +1453,Imidazole_B,"[CH2,CH3][CH2]S[CH2][#6]1=,:[#6]-,:[#7!H0]-,:[#6]=,:[#7]1",*[CH2]S[CH2]C1=CNC=N1 +1454,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2 +1455,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1 +1456,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1 +1457,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23 +1458,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2 +1459,Naphth_ene_one_A,"c1cc3c4c(c1)cccc4C(=CC3=[OX1])O[CH2,CH3]",*OC1=CC(=O)c2cccc3cccc1c23 +1460,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F +1461,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2 +1462,Coumarin_A,"c1(O[C!H0])[cH][cH]c2c3[cH][cH]c(O[CH2,CH3])[cH]c3-,:[#6](=[OX1])-,:[#8]c2c1",*Oc1[cH][cH]c2c([cH]1)C(=O)Oc1cc(OC)[cH][cH]c12 +1463,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O +1464,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1 +1465,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1 +1466,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1 +1467,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O +1468,Coumarin_G,"c1c([F,Cl,Br,I])cc2c(c1[F,Cl,Br,I])OC(=[N!H0])C(C(=[OX1])[NH2])=[C!H0]2",*c1cc(*)c2c(c1)C=C(C([NH2])=O)C(=N)O2 +1469,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1 +1470,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O +1471,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O +1472,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1 +1473,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH] +1474,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH] +1475,Tetrazole_A,"[CH2,CH3][#6]1=,:[#7]-,:[#7]=,:[#7]-,:[#7]1c2[cH][cH]c(O[CH3])[cH][cH]2",*C1=NN=NN1c1[cH][cH]c(O[CH3])[cH][cH]1 +1476,Misc_aminal_acid,"c1ccc4c(c1)COC(N4C(=[OX1])[CH2,CH3])(C(=[OX1])[OH1])[CH2,CH3]",*C(=O)N1c2ccccc2COC1(*)C(=O)[OH] +1477,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1 +1478,Misc_anilide_A,"c1([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH][cH]c([CH2,CH3])c([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH]1",*c1[cH][cH]c(NC(=O)[CH2][CH2]cc)[cH]c1NC(=O)[CH2][CH2]cc +1479,Misc_anilide_B,"c1([N!H0]C(=[OX1])[N!H0][CH2][CH2][CH2,CH3])c([CH2,CH3])[cH]c(Br)[cH]c1[CH2,CH3]",*[CH2][CH2]NC(=O)Nc1c(*)[cH]c(Br)[cH]c1* +1480,Misc_anisole_A,"c1(c([cH]c5c([cH]1)c([cH]c([cH]5)c3[cH][cH]c(c([cH]3)O[CH2,CH3])O[CH2,CH3])[N!H0][CH3])O[CH2,CH3])O[CH2,CH3]",*Oc1[cH][cH]c(c2[cH]c(N[CH3])c3[cH]c(O*)c(O*)[cH]c3[cH]2)[cH]c1O* +1481,Misc_anisole_B,"c1([cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH][cH]1)C(=[OX1])[CH2]N([CH2,CH3])c2ccc([CH2,CH3])cc2",*Oc1[cH][cH]c(C(=O)[CH2]N(*)c2ccc(*)cc2)[cH]c1O* +1482,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3] +1483,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1 +1484,Misc_furan_A,"c3c([CH2,CH3])c([CH2,CH3])oc3[CH2]N[CH2][C!H0](O[CH2,CH3])[CH2]Oc1ccc2c(O[CH2]O2)c1",*OC([CH2]N[CH2]c1cc(*)c(*)o1)[CH2]Oc1ccc2c(c1)O[CH2]O2 +1485,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1 +1486,Misc_phthal_thio_N,"c1(c2ccccc2)nc(N([CH2,CH3])[CH2][CH2]NC(=[OX1])c3c(C(=[OX1])[OH1])cccc3)sn1",*N([CH2][CH2]NC(=O)c1ccccc1C(=O)[OH])c1nc(c2ccccc2)ns1 +1487,Misc_pyridine_OC,"[OX1]=C(c1[cH]c(O[CH3])nc(O[CH3])[cH]1)[N!H0][C!H0]([CH2,CH3])[CH2,CH3]",*C(*)NC(=O)c1[cH]c(O[CH3])nc(O[CH3])[cH]1 +1488,Misc_pyrrole_benz,"[#7]1(-c2[cH][cH][cH][cH]c2C(=[OX1])[N!H0][C!H0]([CH2,CH3])[CH2]O-cc)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",*C([CH2]Occ)NC(=O)c1[cH][cH][cH][cH]c1N1C=CC=C1 +1489,Misc_pyrrole_thiaz,"c1([C!H0]([CH2,CH3])[CH2][CH2]N[CH2]c2[n!H0]ccc2)nc(-c3ccccc3)[c!H0]s1",*C([CH2][CH2]N[CH2]c1cccn1)c1nc(-c2ccccc2)cs1 +1490,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH] +1491,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH] +1492,Misc_urea_A,"c1(C([CX4])([CX4])[N!H0]C(=[OX1])N([CH2][CH2,CH3])[CH2][CH2][CH2][CH2]-cc)[cH][cH][cH]c(C(=[CH2])[CH2,CH3])[cH]1",*[CH2]N([CH2][CH2][CH2][CH2]cc)C(=O)NC(C)(C)c1[cH][cH][cH]c(C(*)=C)[cH]1 +1493,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1 +1494,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1 +1495,Pyrazole_amino_A,"[#6]1=,:[#6]([NH2])-,:[#7]-,:[#7]=,:[#6]1-[#6]2=,:[#6]([CH2,CH3])-,:[#8]-,:[#6!H0]=,:[#6!H0]2",*C1=C(C2=NNC([NH2])=C2)C=CO1 +1496,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1 +1497,Indole_3yl_alk_B,"c12[cH][cH][cH][cH]c1-,:[#6]([CH2,CH3])=,:[#6](-cc)-,:[#7]2-!@cc",*C1=C(cc)N(cc)c2[cH][cH][cH][cH]c21 +1498,Mannich_B,"c1c[cH]c2O[CH2]N(ccO[CH2,CH3])[CH2]c2[cH]1",*OccN1[CH2]Oc2[cH]cc[cH]c2[CH2]1 +1499,Mannich_catechol_A,"[cH]1c([#8])c([#8])[cH]c2c1O[CH2]N([CH2,CH3])[CH2]2",*N1[CH2]Oc2[cH]c(O)c(O)[cH]c2[CH2]1 +1500,Dyes7A,"c1ccccc1N([CH2,CH3])[C!H0]=[C!H0]C=!@[C!H0][C!H0]=CC=&@Nc2ccccc2",*N(C=CC=CC=CC=Nc1ccccc1)c1ccccc1 +1501,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1 +1502,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1 +1503,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH] +1504,Retinoic acid derivatives_1,"[$([OH1][CX3](=[OX1])c1[cH][cH]c(-c2c[cH]c3[cH]c([H,CX4])c([H,CX4])[cH]c3[cH]2)[cH][cH]1),$([OH1][CX3](=[OX1])c1[cH]c2[cH]cc(-c3[cH]c([H,CX4])c([H,CX4])[cH][cH]3)[cH]c2[cH][cH]1)]",* +1505,Thiazole_amine_I,"[CH2,CH3][N!H0]C=N[N!H0][#6]1=,:[#7]-,:[#6](-cc)=,:[#6!H0]-,:[#16]1",*NC=NNC1=NC(cc)=CS1 +1506,Indol_3yl_alk,"[H,CH2,CH3][#7]1-,:[#6]([CH2,CH3,$([a!c](:[#6]-,:[#7])),$([C!H0][#7]),$([C!H0]([CH2,CH3])[N!H0][CH2,CH3]),$([C!H0]([CH2,CH3])[CH2][N!H0][CH2,CH3])])=,:[#6]([CX4!H0])-,:c2[cH]cccc12",*C1=C(C)c2[cH]cccc2N1* +1507,Tetrazole_hzide,"a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])[N!H0][N!H0][#6]2=,:[#7]-,:[#7]=,:[#7]-,:[#7]2[#6]",CN1N=NN=C1NNC(=O)C=C*1:*:*:*:*:*:1 +1508,Three-membered heterocycles (LS),[!#6!#1]1~*~*~1,*1~*~*~1 +1509,Three-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~1,*1~C~C~1 +1510,Saturated three-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-1,*1CC1 +1511,Unsaturated three-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1~[#6]=[#6]~1),$([!#1!#6]1=[#6]~[#6]~1)]",* +1512,Three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[#6]~1,*1~*~C~1 +1513,Saturated three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[#6]-1,*1*C1 +1514,Unsaturated three-membered heterocycles with two heteroatoms (LS),"[$([!#1!#6]1=[!#1!#6]~[#6]~1),$([!#1!#6]1~[!#6!#1]=[#6]~1)]",* +1515,Three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~1,*1~*~*~1 +1516,Saturated three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-1,*1**1 +1517,Unsaturated three-membered heterocycles with three heteroatoms (LS),[!#1!#6]1~[!#1!#6]=[!#1!#6]~1,*1~*=*~1 +1518,Three-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~1,*1~*~*~1 +1519,Three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6&R1]~[#6&R1]~1,*1~C~C~1 +1520,Saturated three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6&R1]-[#6&R1]-1,*1CC1 +1521,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1 +1522,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1 +1523,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1 +1524,Unsaturated three-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1~[#6R1]=[#6R1]~1),$([!#1!#6;R1]1=[#6R1]~[#6R1]~1)]",* +1525,Azirines (HS),"[$([#7R1]1-[#6R1]=[#6R1]-1),$([#7R1]1=[#6R1]-[#6R1]-1)]",* +1526,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1 +1527,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1 +1528,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1 +1529,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1 +1530,Three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~1,*1~*~C~1 +1531,Saturated three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-1,*1*C1 +1532,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1 +1533,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1 +1534,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1 +1535,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1 +1536,Unsaturated three-membered heterocycles with two heteroatoms (HS),"[$([!#1!#6;R1]1=[!#1!#6;R1]~[#6R1]~1),$([!#1!#6;R1]1~[!#6!#1;R1]=[#6R1]~1)]",* +1537,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1 +1538,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1 +1539,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1 +1540,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1 +1541,Three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~1 +1542,Saturated three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**1 +1543,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1 +1544,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1 +1545,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1 +1546,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1 +1547,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1 +1548,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1 +1549,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1 +1550,Unsaturated three-membered heterocycles with three heteroatoms (HS),[!#1!#6;R1]1-[!#6!#1;R1]=[!#6!#1;R1]1,*1*=*1 +1551,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1 +1552,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1 +1553,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1 +1554,Four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~1)]",* +1555,Saturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1-[!#6!#1]-[#6]-[#6]-1),$([!#6!#1]1-[#6]-[!#6!#1]-[#6]-1)]",* +1556,Unsaturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]=[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]=[#6]~1),$([!#6!#1]1=[#6]~[!#6!#1]~[#6]~1)]",* +1557,Four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~C~*~1 +1558,Saturated four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[#6]-1,*1*C*1 +1559,Unsaturated four-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]=[#6]~1)]",* +1560,Four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~1 +1561,Saturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1***1 +1562,Unsaturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*=*~1 +1563,Four-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~1 +1564,Four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~1 +1565,Saturated four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6R1]-[#6R1]-[#6R1]-1,*1CCC1 +1566,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1 +1567,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1 +1568,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1 +1569,Unsaturated four-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]=[#6R1]~[#6R1]~1)]",* +1570,Azetines (HS),"[$([#7R1]1=[#6R1]-[#6R1]-[#6R1]-1),$([#7R1]1-[#6R1]=[#6R1]-[#6R1]-1)]",* +1571,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1 +1572,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1 +1573,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1 +1574,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1 +1575,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1 +1576,Four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1577,Saturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-[#6R1]-1),$([!#6!#1;R1]1-[#6R1]-[!#6!#1;R1]-[#6R1]-1)]",* +1578,Diazetidines (HS),"[$([NR1]1[CR1][CR1][NR1]1),$([NR1]1[CR1][NR1][CR1]1)]",* +1579,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1 +1580,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1 +1581,Dioxetanes (HS),"[$([OR1]1[OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]1)]",* +1582,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1 +1583,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1 +1584,Dithietanes (HS),"[$([SX2R1]1[SX2R1][CR1][CR1]1),$([SX2R1]1[CR1][SX2R1][CR1]1)]",* +1585,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1 +1586,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1 +1587,Unsaturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]=[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]=[#6R1]~1),$([!#6!#1;R1]1=[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1588,Diazetines (HS),"[$([#7]1=,:[#7]-,:[#6]-,=,:[#6]-,:1),$([#7]1-,:[#7]=,:[#6]-,:[#6]-,=,:1),$([#7]1-,:[#7]-,:[#6]=,:[#6]-,=,:1),$([#7]1=,:[#6]-,:[#7]-,=,:[#6]-,:1)]",* +1589,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1 +1590,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1 +1591,Four-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~1,*1~C~C~C~1 +1592,Saturated four-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-[#6]-1,*1CCC1 +1593,Unsaturated four-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]=[#6]~[#6]~1)]",* +1594,Diazirenes (HS),"[$([#7R1]1-[#7R1]=[#6R1]-1),$([#7R1]1=[#7R1]-[#6R1]-1)]",* +1595,Four-membered heterocycles (LS),[!#6!#1]1~*~*~*~1,*1~*~*~*~1 +1596,Five-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~1,*1~*~*~*~*~1 +1597,Five-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~1 +1598,Saturated five-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCC1,*1CCCC1 +1599,Unsaturated five-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=CCCC1),$([!#6!#1]1C=CCC1),$([!#6!#1]1CC=CC1),$([!#6!#1]1=CC=CC1);!$(n1cccc1)]",* +1600,Aromatic five-membered heterocycles with one heteroatom (LS),[a!#6]1cccc1,*1cccc1 +1601,Five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1602,Saturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCC1),$([!#6!#1]1C[!#6!#1]CC1)]",* +1603,Unsaturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]C-,=CC1),$([!#6!#1]1[!#6!#1]=CCC1),$([!#6!#1]1[!#6!#1]C=CC1),$([!#6!#1]1=C[!#6!#1]-,=CC1),$([!#6!#1]1C[!#6!#1]CC=1),$([!#6!#1]1C[!#6!#1]C=C1)]",* +1604,Aromatic five-membered heterocycles with two heteroatoms (LS),"[$([a!#6]1[a!#6]ccc1),$([a!#6]1c[a!#6]cc1)]",* +1605,Five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1606,Saturated five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]C1)]",* +1607,Aromatic five-membered heterocycles with three heteroatoms (LS),"[$([a!#6]1[a!#6][a!#6]cc1),$([a!#6]1[a!#6]c[a!#6]c1)]",* +1608,Five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~1 +1609,Saturated five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]C1,*1**C*1 +1610,Unsaturated five-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1][!#6!#1]-,=[!#6!#1][#6]1),$([!#6!#1]1[!#6!#1]=[!#6!#1][!#6!#1][#6]1),$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1][#6]=1)]",* +1611,Aromatic five-membered heterocycles with four heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6]c1,*1:*:*c*:1 +1612,Five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~1 +1613,Saturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1****1 +1614,Unsaturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1=[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1**=**1 +1615,Aromatic five-membered heterocycles with five heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6][a!#6]1,*1:*:*:*:*:1 +1616,Five-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~1 +1617,Five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~1 +1618,Saturated five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1]1,*1CCCC1 +1619,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1 +1620,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1 +1621,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1 +1622,Unsaturated five-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1]=[CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1]=[CR1][CR1]1),$([!#6!#1;R1]1=[CR1][CR1]=[CR1][CR1]1);!$(n1cccc1)]",* +1623,Pyrrolines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1624,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1 +1625,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1 +1626,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1 +1627,Dihydrofurans (HS),"[$([OR1]1[CR1]=[CR1][CR1][CR1]1),$([OR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1628,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1 +1629,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1 +1630,Dihydrothiophenes (HS),"[$([SR1]1[CR1]=[CR1][CR1][CR1]1),$([SR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1631,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1 +1632,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1 +1633,Aromatic five-membered heterocycles with one heteroatom (HS),[a!#6;R1]1[cR1][cR1][cR1][cR1]1,*1cccc1 +1634,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1 +1635,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1 +1636,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1 +1637,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1 +1638,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1 +1639,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1 +1640,Five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1)]",* +1641,Saturated five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1]1)]",* +1642,Diazolidines (HS),"[$([NR1]1[NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1]1)]",* +1643,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1 +1644,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1 +1645,Dioxolanes (HS),"[$([OR1]1[OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1]1)]",* +1646,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1 +1647,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1 +1648,Dithiolanes (HS),"[$([SR1]1[SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1]1)]",* +1649,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1 +1650,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1 +1651,Pyrazolines (HS),"[$([NR1]1=[NR1][CR1][CR1][CR1]1),$([NR1]1[NR1]=[CR1][CR1][CR1]1),$([NR1]1[NR1][CR1]=[CR1][CR1]1)]",* +1652,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1 +1653,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1 +1654,Imidazolines (HS),"[$([NR1]1=[CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1]=[CR1][CR1]1),$([NR1]1[CR1][NR1][CR1]=[CR1]1)]",* +1655,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1 +1656,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1 +1657,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1 +1658,Dioxolenes (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]=[CR1]1)]",* +1659,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1 +1660,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1 +1661,Dithiolenes (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]1),$([SR1]1[CR1][SR1][CR1]=[CR1]1)]",* +1662,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1 +1663,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1 +1664,Aromatic five-membered heterocycles with two heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][cR1][cR1][cR1]1),$([a!#6;R1]1[cR1][a!#6;R1][cR1][cR1]1)]",* +1665,Diazoles (HS),"[$([nR1]1[nR1][cR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][cR1]1)]",* +1666,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1 +1667,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1 +1668,Oxazoles (HS),"[$([oR1]1[nR1][cR1][cR1][cR1]1),$([oR1]1[cR1][nR1][cR1][cR1]1)]",* +1669,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1 +1670,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1 +1671,Thiazoles (HS),"[$([sR1]1[nR1][cR1][cR1][cR1]1),$([sR1]1[cR1][nR1][cR1][cR1]1)]",* +1672,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1 +1673,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1 +1674,Five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1675,Saturated five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1676,Triazolidines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1]1)]",* +1677,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1 +1678,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1 +1679,Trioxolanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1]1)]",* +1680,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1 +1681,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1 +1682,Trithiolanes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1]1)]",* +1683,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1 +1684,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1 +1685,"1,2,3-Triazolines (HS)","[$([NR1]1=[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][NR1][CR1][CR1]=1),$([NR1]1[NR1][NR1][CR1]=[CR1]1)]",* +1686,"1,2,4-Triazolines (HS)","[$([NR1]1=[NR1][CR1][NR1][CR1]1),$([NR1]1[NR1]=[CR1][NR1][CR1]1),$([NR1]1[NR1][CR1]=[NR1][CR1]1)]",* +1687,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1 +1688,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1 +1689,Aromatic five-membered heterocycles with three heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][a!#6;R1][cR1][cR1]1),$([a!#6;R1]1[a!#6;R1][cR1][a!#6;R1][cR1]1)]",* +1690,Triazoles (HS),"[$([nR1]1[nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1]1)]",* +1691,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1 +1692,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1 +1693,Oxadiazoles (HS),"[$([oR1]1[nR1][nR1][cR1][cR1]1),$([oR1]1[nR1][cR1][nR1][cR1]1),$([oR1]1[nR1][cR1][cR1][nR1]1),$([oR1]1[cR1][nR1][nR1][cR1]1)]",* +1694,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1 +1695,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1 +1696,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1 +1697,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1 +1698,Five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~1 +1699,Saturated five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1][CR1]1,*1**C*1 +1700,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1 +1701,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1 +1702,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1 +1703,Unsaturated five-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1][!#6!#1;R1]-,=[!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1]=[!#6!#1;R1][!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][#6R1]=1)]",* +1704,Aromatic five-membered heterocycles with four heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][cR1]1,*1:*:*c*:1 +1705,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1 +1706,Oxatriazoles (HS),"[$([oR1]1[nR1][nR1][nR1][cR1]1),$([oR1]1[nR1][nR1][cR1][nR1]1)]",* +1707,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1 +1708,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1 +1709,Thiatriazoles (HS),"[$([sR1]1[nR1][nR1][nR1][cR1]1),$([sR1]1[nR1][nR1][cR1][nR1]1)]",* +1710,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1 +1711,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1 +1712,Five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~1 +1713,Saturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1****1 +1714,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1 +1715,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1 +1716,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1 +1717,Unsaturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1=[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**=**1 +1718,Aromatic five-membered heterocycles with five heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][a!#6;R1]1,*1:*:*:*:*:1 +1719,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1 +1720,Six-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~*~1,*1~*~*~*~*~*~1 +1721,Six-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~C~1 +1722,Saturated six-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCCC1,*1CCCCC1 +1723,Unsaturated six-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1=C~C~C~C~C~1),$([!#1!#6]1~C=C~C~C~C~1),$([!#1!#6]1~C~C=C~C~C~1);!$([a!c]1ccccc1)]",* +1724,Aromatic six-membered heterocycles with one heteroatom (LS),[a!c]1ccccc1,*1ccccc1 +1725,Six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1726,Saturated six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCCC1),$([!#6!#1]1C[!#6!#1]CCC1),$([!#6!#1]1CC[!#6!#1]CC1)]",* +1727,Aromatic six-membered heterocycles with two heteroatoms (LS),"[$([a!c]1[a!c]cccc1),$([a!c]1c[a!c]ccc1),$([a!c]1cc[a!c]cc1)]",* +1728,Six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1729,Saturated six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CCC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]CC1),$([!#6!#1]1C[!#6!#1]C[!#6!#1]C1)]",* +1730,Aromatic six-membered heterocycles with three heteroatoms (LS),"[$([a!c]1[a!c][a!c]ccc1),$([a!c]1[a!c]c[a!c]cc1),$([a!c]1c[a!c]c[a!c]c1)]",* +1731,Six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[!#6!#1]~[#6]~1)]",* +1732,Saturated six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1][!#6!#1]C[!#6!#1]C1),$([!#6!#1]1[!#6!#1]C[!#6!#1][!#6!#1]C1)]",* +1733,Aromatic six-membered heterocycles with four heteroatoms (LS),"[$([a!c]1[a!c][a!c][a!c]cc1),$([a!c]1[a!c][a!c]c[a!c]c1),$([a!c]1[a!c]c[a!c][a!c]c1)]",* +1734,Six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~*~1 +1735,Saturated six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-C-1,*1**C**1 +1736,Aromatic six-membered heterocycles with five heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c]c1,*1:*:*c*:*:1 +1737,Saturated six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1*****1 +1738,Unsaturated six-membered heterocycles with six heteroatoms (LS),[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1739,Aromatic six-membered heterocycles with six heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c][a!c]1,*1:*:*:*:*:*:1 +1740,Six-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~*~1 +1741,Six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~C~1 +1742,Saturated six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1][CR1]1,*1CCCCC1 +1743,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1 +1744,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1 +1745,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1 +1746,Unsaturated six-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1=[CR1]~[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]=[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]~[CR1]=[CR1]~[CR1]~[CR1]~1);!$([a!c]1ccccc1)]",* +1747,Tetrahydropyridines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1][CR1]1)]",* +1748,Dihydropyridines (HS),"[$([NR1]1=[CR1][CR1]-,=[CR1]-,=[CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]-,=[CR1]-,=1),$([NR1]1[CR1]=[CR1][CR1]=[CR1][CR1]1)]",* +1749,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1 +1750,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1 +1751,Aromatic six-membered heterocycles with one heteroatom (HS),[a!c;R1]1[cR1][cR1][cR1][cR1][cR1]1,*1ccccc1 +1752,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1 +1753,Six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~1)]",* +1754,Saturated six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1][!#6!#1;R1][CR1][CR1]1)]",* +1755,Hexahydrodiazines,"[$([NR1]1[NR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1][NR1][CR1][CR1]1)]",* +1756,Dioxanes,"[$([OR1]1[OR1][CR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][CR1][OR1][CR1][CR1]1)]",* +1757,Dithianes,"[$([SR1]1[SR1][CR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][CR1][SR1][CR1][CR1]1)]",* +1758,Dioxines (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]=[CR1]1),$([OR1]1[CR1]=[CR1][OR1][CR1]=[CR1]1)]",* +1759,Aromatic six-membered heterocycles with two heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][cR1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][cR1][a!c;R1][cR1][cR1]1)]",* +1760,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1 +1761,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1 +1762,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1 +1763,Six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1764,Saturated six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1765,Hexahydrotriazines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][NR1][CR1]1)]",* +1766,Trioxanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][OR1][CR1]1)]",* +1767,Trithianes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][SR1][CR1]1)]",* +1768,Aromatic six-membered heterocycles with three heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][a!c;R1][cR1]1)]",* +1769,Triazines (HS),"[$([nR1]1[nR1][nR1][cR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][nR1][cR1]1)]",* +1770,Saturated six-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][!#6!#1;R1][CR1]1)]",* +1771,Hexahydrotetrazines (HS),"[$([NR1]1[NR1][NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][NR1][CR1]1),$([NR1]1[NR1][NR1][CR1][NR1][CR1]1)]",* +1772,Tetroxanes (HS),"[$([OR1]1[OR1][OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][OR1][CR1]1)]",* +1773,Tetrathianes (HS),"[$([SR1]1[SR1][SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][SR1][CR1]1)]",* +1774,Aromatic six-membered heterocycles with four heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][a!c;R1][cR1][a!c;R1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][a!c;R1][cR1]1)]",* +1775,Tetrazines (HS),"[$([nR1]1[nR1][nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][nR1][cR1][nR1][cR1]1),$([nR1]1[nR1][cR1][nR1][nR1][cR1]1)]",* +1776,Six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~*~1 +1777,Saturated six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[CR1]-1,*1**C**1 +1778,Aromatic six-membered heterocycles with five heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][cR1]1,*1:*:*c*:*:1 +1779,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1 +1780,Six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~*~1 +1781,Saturated six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1*****1 +1782,Unsaturated six-membered heterocycles with six heteroatoms (HS),[$([!#6!#1;R1]1=[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1783,Aromatic six-membered heterocycles with six heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][a!c;R1]1,*1:*:*:*:*:*:1 +1784,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1 +1785,Six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~*~1 +1786,Dithiines (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]=[CR1]1),$([SR1]1[CR1]=[CR1][SR1][CR1]=[CR1]1)]",* +1787,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1 +1788,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1 +1789,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1 +1790,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C +1791,Allyl halides,"[CX3]=[CX3][CX4][F,Cl,Br,I]",*CC=C +1792,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF +1793,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl +1794,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr +1795,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI +1796,Vinyl fluorides,F[CX3]=[CX3],C=CF +1797,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl +1798,Vinyl bromides,Br[CX3]=[CX3],C=CBr +1799,Vinyl iodides,I[CX3]=[CX3],C=CI +1800,Alkynyl fluorides,F[CX2]#[CX2],C#CF +1801,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl +1802,Alkynyl iodides,I[CX2]#[CX2],C#CI +1803,Alkynyl bromides,Br[CX2]#[CX2],C#CBr +1804,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC +1805,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc +1806,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc +1807,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH] +1808,"1,3 – Diphenols",c([OH1])[aR1]c([OH1]),[OH]c*c[OH] +1809,"1,4 - Diphenols",c1([OH1])aac([OH1])aa1,[OH]c1*:*c([OH])*:*1 +1810,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH] +1811,"1,3 – Dithiophenols",c([SH1])[aR1]c([SH1]),[SH]c*c[SH] +1812,"1,4 – Dithiophenols",c1([SH1])aac([SH1])aa1,[SH]c1*:*c([SH])*:*1 +1813,"1,2 – Aminophenols","c([OH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[OH] +1814,"1,3 – Aminophenols","c([OH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[OH] +1815,"1,4 – Aminophenols","c1([OH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([OH])*:*1 +1816,"1,2 – Aminothiophenols","c([SH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[SH] +1817,"1,3 – Aminothiophenols","c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[SH] +1818,"1,4 – Aminothiophenols","c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([SH])*:*1 +1819,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C +1820,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C +1821,Carbonic acid esters,"[#1,#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*OC(=O)OC +1822,Phosphonic acid amides,[OX1]=[Pv5X4]([NX3])([#6])[!#6!$([SX2])],*P(C)(N)=O +1823,Aldehyde,[CX3H1](=O)[#6],C[CH]=O +1824,AliphaticEther,[!$(C=O);$([C&!a])][OX2&H0][!$(C=O);$([C&!a])],*O* +1825,AminoAcids,"[$([NX3,NX4+][CX4H]([*])[CX3](=[OX1])[O,N]),$([$([$([NX3H2,NX4H3+]),$([NX3H](C)(C))][CX4H2][CX3](=[OX1])[OX2H,OX1-,N])])]",* +1826,AromaticHalogen,"[$([a][F,Cl,I])]",* +1827,AromaticNGroups,"[$([a]N(~O)~O),$([a]N([#1])[*]),$([a]N([#1])[!#1])]",* +1828,AromaticSulphonicAcid,"[$([#16X4](=[OX1])(=[OX1])([a])[OX2H,OX1H0-]),$([#16X4+2]([OX1-])([OX1-])([a])[OX2H,OX1H0-])]",* +1829,AzoGroup,[$([!R&N]=[!R&N])],* +1830,CyanoGroupOnMoreThanEightAtomsChain,[N]#[C]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0],*~*~*~*~*~*~*~*~C#N +1831,Epoxide,[$(C1OC1)],* +1832,Esters,[#6][CX3](=O)[$([OX2H0]([#6])[#6])],*C(C)=O +1833,Formaldehyde,[CX3H2](=O),C=O +1834,Ketone,[C][C](=O)[C],CC(C)=O +1835,MoreThanTwoHydroxyOnAromaticRing,"[$([a&R]([OX2H])[a&R]([OX2H])),$([a&R]([OX2H])a[a&R]([OX2H])),$([a&R]([OX2H])aa[a&R]([OX2H]))]",* +1836,Nitrile,[C]#[N],C#N +1837,NNitroso,[$(NN=O)],* +1838,PyridineRing,[$(n1ccccc1)],* +1839,TerminalTertButyl,[$([C]([CH3])([CH3])([CH3])([*]))],* +1840,TertiaryAmine,[!R&NX3&H0],* +1841,TriazineRing,"[$(n1nnccc1),$(n1ncncc1),$(n1cncnc1)]",* +1842,Trifluoromethyl,[$([*]C(F)(F)F)],* +1843,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1 +1844,Phenoxazines,"[OX1,N]=[#6]1-,:[#6]=,:[#6]2-,:[#16X2,#8X2]-,:[#6]3=,:[#6]-,:[#6](=,:[#6]-,:[#6]=,:[#6]3-,:[#7]=,:[#6]2-,:[#6]=,:[#6]1)",*=C1C=CC2=NC3=CC=CC=C3*C2=C1 +1845,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1 +1846,Imidazotriazoles,"[c,n]1cnn2c([NH])cnc12",[NH]c1cnc2*cnn12 +1847,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21 +1848,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21 +1849,NCCN,"[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]-[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]",** +1850,Picolylamines_A,"[$([NX3][CH2]c1ncnc([NX3])c1),$([NX3][CH2]c1nccc([NX3])n1)]",* +1851,Picolylamines_B,"[$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]n([H,CH3])cc1),$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]ccn1[H,CH3])]",* +1852,Picolylamines_C,"c1cccnc1[CH2!R][NX3!R]([H,CH3])[CH2!R]",*N([CH2])[CH2]c1ccccn1 +1853,Bis-picolylamines,"[nv3X2]c([c,s,n])[CX4][NX3]([H,C])[CX4]c([c,s,n])[nv3X2,nv3X3H1]",*N(Cc(*)*)Cc(*)n +1854,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1 +1855,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1 +1856,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n +1857,Diarylmethanes,"[$(c1[nX2][c,n][c,n][c,n]1),$([cr6][nX2r6])][CX4H2!R][$(c2[nX2][c,n][c,n][c,n]2),$([cr6][nX2r6])]",*[CH2]* +1858,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12 +1859,Heterylamides_A,"[$([cr5][n,s;r5][n,o;r5]),$([cr5]([nr5])[s,o,n;r5])][Nv3X3H1!R][CX3!R](=[OX1])[$([cr5][nv3X2r5]),$(c1ncccc1),$(c1c([OX2][CH3])cccc1)]",*[NH]C(*)=O +1860,Heterylamides_B,"[$(c1nnc[o,n]1),$(c1nccs1)][Nv3X3H!R][C!R](=[OX1])[CX4!H0]([H,CX4])[SX2,n]cc",*[NH]C(=O)C(*)*cc +1861,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1 +1862,8-Quinolinols,"[H,C][OX2]c1c([CX4][NX3])ccc2cccnc21",*Oc1c(CN)ccc2cccnc12 +1863,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1 +1864,Perchloroquinone,"[OX1]=[CX3]1C([F,Cl,Br,I])=C([F,Cl,Br,I])[CX3](=[OX1])C([F,Cl,Br,I])=C1[F,Cl,Br,I]",*C1=C(*)C(=O)C(*)=C(*)C1=O +1865,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn +1866,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1 +1867,A3,"[OH][CX3](=[OX1])[#6]1-,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:1",O=C([OH])C1=CC=CC=*1 +1868,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1 +1869,B5,"[#6]1=,:[#6]-,:[#6]=,:[#6]([OH])-,:[#6]2=,:[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]2",[OH]C1=CC=CC2=C1*=CC=C2 +1870,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12 +1871,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12 +1872,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12 +1873,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1 +1874,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1 +1875,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1 +1876,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1 +1877,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1 +1878,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1 +1879,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1 +1880,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12 +1881,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12 +1882,"C10, C11","[CH3]c1nc([OH])cc([OH,CH3])n1",*c1cc([OH])nc([CH3])n1 +1883,"C10*, C11*","[CX4]c1nc([OH])cc([OH,CX4])n1",*c1cc([OH])nc(C)n1 +1884,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH] +1885,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S +1886,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH] +1887,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH] +1888,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S +1889,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C +1890,"E6, E8","O=[#6]1-,:[#7]([H,CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",*N1C=CC=C([OH])C1=O +1891,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH] +1892,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C +1893,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S +1894,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S +1895,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH] +1896,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH] +1897,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH] +1898,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH] +1899,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1 +1900,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1 +1901,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1 +1902,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1 +1903,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1 +1904,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1 +1905,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21 +1906,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1 +1907,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12 +1908,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH] +1909,"G9,G10","c1ccc(c(c1)[OH,SH])[OX2][CX4]",*c1ccccc1OC +1910,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH] +1911,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH] +1912,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH] +1913,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH] +1914,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH] +1915,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1 +1916,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1 +1917,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1 +1918,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1 +1919,H8 - H12,"C[CX3](=[OX1])[CX4!H0]([H,CX4,Cl])[CX3](=[OX1])C",*C(C(C)=O)C(C)=O +1920,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O +1921,Salts_C,"[!#1!#2!#5!#6!#7!#8!#9!#10!#14!#15!#16!#17!#18!#32!#33!#34!#35!#36!#51!#52!#53!#54!#84!#85!#86]~[#6,#7,#8,#16]",*~* +1922,Pt,[Pt],[Pt] +1923,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +1924,β-lactones and γ- sultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +1925,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O +1926,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +1927,Heterocyclic Polycyclic Aromatic Hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +1928,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1929,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1 +1930,Azafluorenones,"[OX1,SX1]=[#6X3]1c2c([nX2][cX3,nX2,nX3][cX3,nX2,nX3][cX3,nX2,nX3]2)[c,n]2c1[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])]2",*=C1c2cccc*2c2n*:*:*c21 +1931,Cyanothioazinones,"[SX1]=[#6X3]1-,:[#7X3H1]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#7X2,#6X3!$([#6X3]=[A])]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#6X3]1([CX2]#[NX1])",N#CC1=**=*[NH]C1=S +1932,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1 +1933,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1934,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1 +1935,Benzoxathiolones,"[$([#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]),$([#8]1-,:[#6](-,:[#16]c4ccc(cc14)[#7,#8])=[OX1,SX1])]",* +1936,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21 +1937,Pyrazolones,"[#7X2]1=,:[#6X3]-,:[#6X3](-,:[#6X3](-,:[#7X3]1)=[SX1,OX1])=,:[#6X3H1](-,:[#7X3H1])",*=C1NN=CC1=[CH][NH] +1938,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1 +1939,Pyrimidinones_A,"[OX1,SX1]=[#6X3]1[#7X3](-,:[#7X2]=,:[#6X3][NX3H1][#6])-,:[cX3!$([#6X3]=[A])]=,:[#7X2]-,:[cX3!$([#6X3]=[A])]=,:[cX3!$([#6X3]=[A])]1",*=C1c=cN=cN1N=C[NH]C +1940,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12 +1941,Pyrimidinones_C,"[OX1,SX1]=[#6X3]1[#7X3]-,:[#6X3!$([#6X3]=[A])](-[NX3])=,:[#7X2]-,:[#6X3]2([nX2][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])]c12)",*=C1NC(N)=NC2nCCCc21 +1942,Pyrimidinodiones,"[#6X3]1(=[OX1,SX1])-,:[#7X3H1]-,:[#6X3](=[OX1,SX1])-,:[#7X3,#7X2]~[#6X3]([#7X2,#7X3;R1])-,:[#6X3]1[sX2r5R1,nX2r5R1,$([nx2r6R1]([cX3])[cX3])]",*C1C(*)C(=*)[NH]C(=*)*~1 +1943,Thienopyrimidinone_A,"[OX1,SX1]=[#6X3]1-,:[#7X3H1]-,:[#6X4]-,:[#7X3H1]-,:[#6]2-,:[#16X2,#8X2]-,:[#6]3[CX4][NX3,CX4][CX4][CX4]-,:[#6]3-,:[#6]12",*=C1[NH]C[NH]C2*C3C*CCC3C21 +1944,Piperazinediones,"[#7X3]1-,:[#6X3](=[OX1,SX1])-,:[#6X3](=[OX1,SX1])-,:[NX3]-,:[#6X3]2[cX3!$([#6X3]=[A])][cX3]([NX3H1][CX3]=[OX1])[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3]12",*=C1NC2cc([NH]C=O)ccc2NC1=* +1945,4-Heteryl-thiazoles,"s1[c,nX2][c,nX2](-c(c)[nX2,nX3,sX2])[nX2]c1",*c(c)-*1:*scn1 +1946,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1 +1947,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH] +1948,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1 +1949,Cyanothioethers,"[NX1]#[CX2][CX4H2][SX2]c1n[c,n][c,n][c,n]n1",N#C[CH2]Sc1n*:*:*n1 +1950,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1 +1951,Fused azacycles_A,"[nX2R1][c,n;R2]1[c,n;R2]([c,n;R1])[c,n][c,n][c,n;R2]([c,n;R1])[nR2]1[nX2R1]",*:*1:*:*:*(:*)n(n)*:1n +1952,Fused azacycles_B,"[NX1]#[CX2]c1[c!$([#6]=[OX1])]n[n,c!$([#6]=[OX1])]2[c,n][c!$([#6]=[OX1])][c!$([#6]=[OX1])]nc12",N#Cc1cn*2:*ccnc21 +1953,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12 +1954,Arylethanolamines,"[$([NX3]([CX4,H])([CX4,H])[CX4]),$([OX2]([H,CX4])[CX4])][CX4!H0][CX4H2][NX3H1]c[nX2r6R1][nX2,nX3][nX2,cX3;R1][cX3,nX2][cX3,nX2][sX2,cX3][cX3]",*C[CH2][NH]cn*:*:*:*:*c +1955,Azaspironones,"[X4;R2]12(-,:;@[#6X3]-,:;@[#6X3]-,:;@[#7X3]-,:;@[#6X3]-,:;@1)-,:;@[#16X2]-,:;@[#6X3]=,:;@[#7X2]-,:;@[#7X3]-,:;@2",C1C*2(CN1)NN=CS2 +1956,Radical,[#16;X3v3+0],S +1957,N⋯X halogen bonding,"N[F,Cl,Br,I]",*N +1958,Charged atoms,"[+,-]",* +1959,Benzyl Imidazole scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*-,=*c:3:c:c:c:c:c:3",*(*c1ccccc1)*1:*:*2:*c*c*:2:*:1 +1960,6-Phenyl Napthaline type scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s][c,n,o,s]2)*~*c:3:c:c:c:c:c:3",*(~*c1ccccc1)*1:*:*:*2:*c*c*:2:*:1 +1961,2-(2-(1H-pyrrol-2-yl)ethyl)-1H-benzoimidazole scaffold,"[c,n]:1:c:c2:c(:[c,n]:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*~*c3ccc*3",*(~*c1ccc*1)*1:*c2*c*cc2*:1 +1962,2 - Olefin group,"[$([CX3H2]=[CX3H1]),$([CX3H1]=[CX3H1]),$([CX3H2]=[CX3H0]),$([CX3H1]=[CX3H0]),$([CX3H0]=[CX3H0])]",* +1963,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +1964,6 - Methanol,[CX4H3][OX2H1],[CH3][OH] +1965,7 - Water,[OX2H2],O +1966,9 - Сarbonyl,"[$([CX4H3][CX3](=[OX1])[#6]),$([CX4H2][CX3H0](=[OX1])[#6])]",* +1967,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O +1968,11 - Acetate group,"[$([CX4H3][CX3](=[OX1])[OX2][#6]),$([CX4H2][CX3](=[OX1])[OX2][#6])]",* +1969,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +1970,14 - Primary amine,"[$([CX4H3][NX3H2]),$([CX4H2][NX3H2]),$([CX4H1][NX3H2])]",* +1971,16 - Tertiary amine,"[$([CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]),$([CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6])]",* +1972,19 - CCN,"[$([CX4H3][CX2]#[NX1]),$([CX4H2][CX2]#[NX1])]",* +1973,20 - COOH,"[$([CX3H0](=[OX1])[OX2H1]),$([CX3H1](=[OX1])[OX2H1])]",* +1974,21 - CCl,"[$([CX4H2!$([CX4H2](Cl)Cl)]Cl),$([CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl]),$([CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl])]",* +1975,22 - CCl2,"[$([CX4H2]([Cl])[Cl]),$([CX4H1]([!Cl!F])([Cl])[Cl]),$([CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F])]",* +1976,23 - CCl3,"[$([CX4H1]([Cl])([Cl])[Cl]),$([CX4H0]([!Cl!F])([Cl])([Cl])[Cl])]",* +1977,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +1978,26 - CNO2,"[$([CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)])]",* +1979,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S +1980,29 - CH3SH,"[$([CX4H3][SX2H1]),$([CX4H2][SX2H1])]",* +1981,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +1982,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +1983,32 - Iodo compounds,[I],I +1984,33 - Bromo compounds,[Br!$([Br][cR])],Br +1985,34 - Carbon triple bond,"[$([CX2H1]#[CX2H0]),$([CX2H0]#[CX2H0])]",* +1986,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +1987,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +1988,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl +1989,39 - DMF,"[$([CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3]),$([CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2])]",* +1990,40 - CF2,"[$([CX4](F)(F)(F)[!Cl!F]),$([CX4](F)(F)([!F!Cl!H])([!F!Cl!H])),$([CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]))]",* +1991,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +1992,42 - SiH2,"[$([SiX4H3]),$([SiX4H2]([!$([OX2])])([!$([OX2])])),$([SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])])),$([SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]))]",* +1993,43 - SiO,"[$([SiX4H2][OX2]),$([SiX4H1][OX2]),$([SiX4H0][OX2])]",* +1994,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +1995,47 - OCCOH,"[$([OX2H0!R][CX4H2][CX4H2][OX2H1]),$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +1996,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +1997,52 - Sulphones,"[$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2]),$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1])]",* +1998,53 - Oxides,"[$([CX4H2]1[OX2][CX4H2]1),$([CX4H2]1[OX2][CX4H1]1),$([CX4H2]1[OX2][CX4H0]1),$([CX4H1]1[OX2][CX4H1]1),$([CX4H1]1[OX2][CX4H0]1),$([CX4H0]1[OX2][CX4H0]1)]",* +1999,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2000,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C +2001,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH] +2002,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C +2003,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C +2004,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C +2005,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c +2006,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +2007,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH] +2008,17 - H2O (7 - Water),[OX2H2],O +2009,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O +2010,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O +2011,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O +2012,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O +2013,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O +2014,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +2015,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3] +2016,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2] +2017,28 - THF (13 - Ether),[OX2R!r3!$([OX2]C=[OX1])!$([OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1)]([R])[CX4H2R],*O[CH2] +2018,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2] +2019,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2] +2020,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2] +2021,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3] +2022,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2] +2023,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH] +2024,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3] +2025,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2] +2026,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1 +2027,39 - C5H4N (18 - Pyridine),"[$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]:[cX3H1]1)]",* +2028,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N +2029,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N +2030,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH] +2031,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH] +2032,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl +2033,46 - CHCl (21 - CCl),[CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl],*[CH](*)Cl +2034,47 - CCl (21 - CCl),[CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl],*C(*)(*)Cl +2035,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl +2036,49 - CHCl2 (22 - CCl2),[CX4H1]([!Cl!F])([Cl])[Cl],*[CH](Cl)Cl +2037,50 - CCl2 (22 - CCl2),[CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F],*C(*)(Cl)Cl +2038,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl +2039,52 - CCl3 (23 - CCl3),[CX4H0]([!Cl!F])([Cl])([Cl])[Cl],*C(Cl)(Cl)Cl +2040,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +2041,55 - CH3NO2 (26 - CNO2),"[CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH3] +2042,56 - CH2NO2 (26 - CNO2),"[CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH2] +2043,57 - CHNO2 (26 - CNO2),"[CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH] +2044,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S +2045,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH] +2046,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH] +2047,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +2048,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +2049,64 - I (32 - Iodo compounds),[I],I +2050,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br +2051,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C +2052,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C +2053,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +2054,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +2055,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl +2056,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O +2057,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O +2058,74 - CF3 (40 - CF2),[CX4](F)(F)(F)[!Cl!F],*C(F)(F)F +2059,75 - CF2 (40 - CF2),[CX4](F)(F)([!F!Cl!H])([!F!Cl!H]),*C(*)(F)F +2060,76 - CF (40 - CF2),[CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]),*C(*)(*)F +2061,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +2062,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3] +2063,79 - SiH2 (42 - SiH2),[SiX4H2]([!$([OX2])])([!$([OX2])]),*[SiH2]* +2064,80 - SiH (42 - SiH2),[SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[SiH](*)* +2065,81 - Si (42 - SiH2),[SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[Si](*)(*)* +2066,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2] +2067,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH] +2068,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si] +2069,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +2070,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl +2071,87 - CCl2F (45 - CClF),[CX4H0]([Cl])([Cl])([F])[!Cl!F],*C(F)(Cl)Cl +2072,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl +2073,89 - HCClF (45 - CClF),[CX4H1](Cl)(F)([!F!Cl]),*[CH](F)Cl +2074,90 - CClF2 (45 - CClF),[CX4H0](Cl)(F)(F)[!Cl!F],*C(F)(F)Cl +2075,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl +2076,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl +2077,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl +2078,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O +2079,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O +2080,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O +2081,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O +2082,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O +2083,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O +2084,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH] +2085,101 - C2H4O2 (47 - OCCOH),"[$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +2086,102 - CH3S (48 - CH2S),[CX4H3][SX2H0][*],*S[CH3] +2087,103 - CH2S (48 - CH2S),[CX4H2][SX2H0!$([SX2H0]([CX4H2])[CX4H3])][*],*S[CH2] +2088,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +2089,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1 +2090,107 - C4H3S (50 - Thiophene),"[$([#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H0]=,:1),$([#6X3H1]1-,:[#16X2]-,:[#6X3H0]=,:[#6X3H1]-,:[#6X3H1]=,:1)]",* +2091,109 - NCO (51 - NCO),[*][NX2]=[CX2]=[OX1],*N=C=O +2092,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O +2093,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O +2094,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1 +2095,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1 +2096,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1 +2097,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1 +2098,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1 +2099,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1 +2100,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2101,phosphorodithionate,[$([SX2H0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2102,"O,O-diethylphosphorodithionate",CCOP(=S)(OCC)SC([*:1]),CCOP(=S)(OCC)SC[*:1] +2103,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O +2104,"O,O-dimethylphosphoryl",COP(=O)(O([*:1]))OC,COP(=O)(OC)O[*:1] +2105,phosphorothionate,[$([OH0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2106,diethylphosphorothionate,CCOP(=S)(O([*:1]))OCC,CCOP(=S)(OCC)O[*:1] +2107,O-phenyl phenylphosphonothioate,S=P(O([*:1]))(Oc1ccc([*:1])cc1)c1ccccc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])c1ccccc1 +2108,O-phenyl phosphonothioate,S=P(O([*:1]))(O([*:1]))Oc1ccc([*:1])cc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])O[*:1] +2109,carbamate,[$(N([!H])C(=O)[OH0])]C(=O)[OH0],*C(O)=O +2110,"2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-(aminosulfanyl)-N-methylcarbamate",CN(SN([*:1])([*:1]))C(=O)Oc1cccc2CC(C)(C)Oc12,CN(SN([*:1])[*:1])C(=O)Oc1cccc2c1OC(C)(C)C2 +2111,methyl(propoxysulfanyl) carbamate,CN(SOCCC([*:1]))C(=O)O([*:1]),CN(SOCCC[*:1])C(=O)O[*:1] +2112,phenyl carbamate,O=C(N([*:1]))Oc1ccccc([*:1])1,O=C(N[*:1])Oc1ccccc1[*:1] +2113,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C +2114,dimethylcarbamate,CN(C)C(=O)O([*:1]),CN(C)C(=O)O[*:1] +2115,barbiturates,*C1(*)[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]1=O,*C1(*)C(=O)NC(=O)NC1=O +2116,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1 +2117,Phenothiazine,*-[#7]-1-c2ccccc2-[#16]-c2ccccc-12,*N1c2ccccc2Sc2ccccc21 +2118,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1 +2119,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1 +2120,"2,4-dichloro-benzene-1,3-dicarbonitrile",N#Cc1c([*:1])c([*:1])c(Cl)c(C#N)c1Cl,N#Cc1c(Cl)c(C#N)c([*:1])c([*:1])c1Cl +2121,R1 - Reactive alkyl halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2122,R2 - Acid halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2123,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O +2124,R4 - Sulphate esters,"COS(=O)O[C,c]",*OS(=O)OC +2125,R5 - Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2126,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O +2127,R7 - Peroxides,OO,OO +2128,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2129,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1 +2130,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O +2131,R11 - Isocyanates & Isothiocyanantes,"N=C=[S,O]",*=C=N +2132,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2133,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S +2134,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2135,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-] +2136,R16 - beta carbonyl quaternary Nitrogen,"C(=O)C[N+,n+]",*CC=O +2137,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O +2138,"R18 - Quaternary C,Cl,I,P or S","[C+,Cl+,I+,P+,S+]",* +2139,R19 - Phosphoranes,C=P,C=P +2140,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl +2141,R21 - Nitroso,[N&D2](=O),N=O +2142,R22 - P/S Halides,"[P,S][Cl,Br,F,I]",** +2143,R23 - Carbodiumide,N=C=N,N=C=N +2144,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+] +2145,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2146,R26 - Cyanohydrins,N#CC[OH],N#CC[OH] +2147,R27 - Acyl cyanides,N#CC(=O),N#CC=O +2148,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O +2149,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2150,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N +2151,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2152,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC +2153,I2 - Compounds with 4 or more acidic groups,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2154,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2155,I4 - Disulphides,SS,SS +2156,I5 - Thiols,[SH],[SH] +2157,"I6 - Epoxides, Thioepoxides, Aziridines","C1[O,S,N]C1",*1CC1 +2158,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2159,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2160,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2161,I10 - Thiocyanate,SC#N,N#CS +2162,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+] +2163,I12 - Thioesters,"C[O,S;R0][C;R0](=S)",C*C=S +2164,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N +2165,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1 +2166,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2167,I16 - Betalactams,N1CCC1=O,O=C1CCN1 +2168,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1 +2169,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2170,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2171,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2172,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2173,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2174,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1 +2175,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2176,"A1 - e.g., carboxylic acid","[OH1][P,C,S](=O)",O=*[OH] +2177,"A2 - e.g.,imide","[NH1]([P,S]=O)([P,S]=O)",O=*[NH]*=O +2178,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1 +2179,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1 +2180,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1 +2181,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O +2182,A8,[nH1]1ncoc1=O,O=c1[nH]nco1 +2183,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1 +2184,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1 +2185,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1 +2186,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1 +2187,A13,[nH1]1occc1=O,O=c1cco[nH]1 +2188,A14,[OH1]c1oncc1,[OH]c1ccno1 +2189,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1 +2190,A16 - tetrazole,[nH1]nnn,nnn[nH] +2191,A17,[nH1](n)nn,nn[nH]n +2192,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1 +2193,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1 +2194,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1 +2195,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1 +2196,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1 +2197,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1 +2198,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1 +2199,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21 +2200,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21 +2201,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21 +2202,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH] +2203,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1 +2204,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH] +2205,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F +2206,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O +2207,A33 - phenol,"[OH1]c1c[c,n]ccc1",[OH]c1c*ccc1 +2208,B1 - primary amine,[NH2][CX4],C[NH2] +2209,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C +2210,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C +2211,B4SUB,"[C,c](=N)N",N*=N +2212,B5EXC,"[C,c](=N)N[C,S](=O)",N=*N*=O +2213,B6,"[$([C,c](=N)N);!$([C,c](=N)N[C,S](=O))]",* +2214,B7EXC,n(:c)(:c):a,*n(c)c +2215,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1 +2216,B8EXC,"[N,n;+1]",* +2217,B9,"[$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]",* +2218,E1 - alkyl and aryl ketones and aldehydes,"[C;H1](=[O,S])[C,c]",*C=* +2219,"E2 - e.g., carboxylic esters","[C,P;H1](=[O,S])[O,S]",**=* +2220,"E3 - e.g., carbonates","[C](=O)([C,c,O,S])[C,c,O,S]",*C(*)=O +2221,E4EXC,C(=O)[OH1],O=C[OH] +2222,E5EXC,C(=O)[SH1],O=C[SH] +2223,E6,"C(=[O,S])(N)Oc",*=C(N)Oc +2224,"E7 - e.g., aryl carbamates","C1(=O)NS(=O)(=O)[C,c]=,:[C,c]1",O=C1*=*S(=O)(=O)N1 +2225,E8SUB,"P(=O)[O,S]",*P=O +2226,E9EXC,P[OH1],[OH]P +2227,E10,"[$(P(=O)[O,S]);!$(P[OH1])]",* +2228,E11,c(=O)(~c)~c,c~c(~c)=O +2229,E12EXC,"[$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)]",* +2230,E12,"[$(c(=O)(~c)~c);!$([$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)])]",* +2231,E13 - imides,C(=O)-N-C=O,O=CNC=O +2232,N1 - pimary amines,[NX3H2][CX4],C[NH2] +2233,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C +2234,N4EXC,"N=[O,C,N,S]",*=N +2235,N5EXC,"N-[C,c,N]=[C,c,N,n,O,S]",*=*N +2236,N6,"[OH1][C,c,N;!$(C=O)]",*[OH] +2237,N7EXC,[OH1]C=C,C=C[OH] +2238,N8EXC,"[OH1]NC=[O,S]",*=CN[OH] +2239,N9,"[$([NX3H2]!:c),$([NX3H1]([CX4])!:c),$([NX3H0]([CX4])([CX4])!:c)]",* +2240,NUC,"[$([NH2][CX4]),$([NH]([CX4])[CX4]),$([OH1][C,c,N;!$(C=O)]),$([$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]);!$(N=[O,C,N,S]);!$(N-[C,c,N]=[C,c,N,n,O,S]);!$([OH1]C=C);!$([OH1]NC=[O,S])]",* +2241,> 2 ester groups,"C(=O)O[C,H1].C(=O)O[C,H1].C(=O)O[C,H1]",*OC=O.*OC=O.*OC=O +2242,2-halo pyridine,"n1c([F,Cl,Br,I])cccc1",*c1ccccn1 +2243,Acid halide,"C(=O)[Cl,Br,I,F]",*C=O +2244,Acyclic C=C-O,C=[C!r]O,C=CO +2245,Acyl cyanide,N#CC(=O),N#CC=O +2246,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O +2247,Aliphatic long chain,[R0;D2][R0;D2][R0;D2][R0;D2],**** +2248,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1 +2249,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1 +2250,Azido group,N=[N+]=[N-],[N-]=[N+]=N +2251,Azo group,N=N,N=N +2252,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1 +2253,Benzidine,"[cR2]1[cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2][cR2]1[cR2]2[cR2][cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2]2",*c1ccc(c2ccc(*)cc2)cc1 +2254,Betaketo/anhydride,"[C,c](=O)[CX4,CR0X3,O][C,c](=O)",O=***=O +2255,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2256,Carbo cation/anion,"[C+,c+,C-,c-]",* +2257,Catechol,"c1c([OH])c([OH,NH2,NH])ccc1",*c1ccccc1[OH] +2258,Charged oxygen or sulfur atoms,"[O+,o+,S+,s+]",* +2259,Chinone (1),"C1(=[O,N])C=CC(=[O,N])C=C1",*=C1C=CC(=*)C=C1 +2260,Chinone (2),"C1(=[O,N])C(=[O,N])C=CC=C1",*=C1C=CC=CC1=* +2261,Conjugated nitrile group,C=[C!r]C#N,C=CC#N +2262,Crown ether,"[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]",*~C~C~*~C~C~* +2263,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1 +2264,Cyanamide,N[CH2]C#N,N[CH2]C#N +2265,Cyanate/aminonitrile/thiocyanate,"[N,O,S]C#N",*C#N +2266,Cyanohydrins,N#CC[OH],N#CC[OH] +2267,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1 +2268,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1 +2269,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1 +2270,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1 +2271,Diaminobenzene (1),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])c([N+R0,NX3R0,nX3R0])[cR2][cR2]1",*c1ccccc1* +2272,Diaminobenzene (2),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2]c([N+R0,NX3R0,nX3R0])[cR2]1",*c1cccc(*)c1 +2273,Diaminobenzene (3),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2][cR2]c1([N+R0,NX3R0,nX3R0])",*c1ccc(*)cc1 +2274,Diazo group,[N!R]=[N!R],N=N +2275,Diketo group,"[C,c](=O)[C,c](=O)",O=**=O +2276,Disulphide,SS,SS +2277,Enamine,[CX3R0][NX3R0],CN +2278,Ester of HOBT,C(=O)Onnn,nnnOC=O +2279,Four member lactones,C1(=O)OCC1,O=C1CCO1 +2280,Halogenated ring (1),"c1cc([Cl,Br,I,F])cc([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1ccc(*)c(*)c1 +2281,Halogenated ring (2),"c1ccc([Cl,Br,I,F])c([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1cccc(*)c1* +2282,Heavy metal,"[Hg,Fe,As,Sb,Zn,Se,se,Te,B,Si]",* +2283,Het-c-het not in ring,"[NX3R0,NX4R0,OR0,SX2R0][CX4][NX3R0,NX4R0,OR0,SX2R0]",*C* +2284,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1 +2285,Hydroxamic acid,C(=O)N[OH],O=CN[OH] +2286,Imine,C=[N!R],C=N +2287,Isolated alkene,"[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]=[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]",*=* +2288,Ketene,C=C=O,C=C=O +2289,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1 +2290,Michael acceptor (1),"C=!@CC=[O,S]",*=CC=C +2291,Michael acceptor (2),"[$([CH]),$(CC)]#CC(=O)[C,c]",*C(=O)C#* +2292,Michael acceptor (3),"[$([CH]),$(CC)]#CS(=O)(=O)[C,c]",*S(=O)(=O)C#* +2293,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O +2294,Michael acceptor (5),"[$([CH]),$(CC)]#CC(=O)O[C,c]",*OC(=O)C#* +2295,N oxide,"[NX4,nX3][OX1]",*O +2296,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1 +2297,N-c-halo,"NC[F,Cl,Br,I]",*CN +2298,N-halo,"[NX3,NX4][F,Cl,Br,I]",** +2299,N-hydroxylpyridine,n[OH],n[OH] +2300,Nitro group,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]",* +2301,N-nitroso,[#7]-N=O,NN=O +2302,Oxime (1),"[C,c]=N[OH]",*=N[OH] +2303,Oxime (2),"[C,c]=NOC=O",*=NOC=O +2304,Oxygen-nitrogen single bond,"[OR0,NR0][OR0,NR0]",** +2305,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F +2306,Peroxide,OO,OO +2307,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1 +2308,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1 +2309,Phosphor,P,P +2310,Phthalimide,"[cR,CR]~C(=O)NC(=O)~[cR,CR]",*~C(=O)NC(~*)=O +2311,Polycyclic aromatic hydrocarbon (1),"a1aa2a3a(a1)[a,A]=,:[a,A]-,:[a,A]=,:[a,A]3A=AA2",*1*=**2:*3:*1:*:*:*:*:3:*=**=2 +2312,Polycyclic aromatichydrocarbon (2),a21aa3a(aa1aaaa2)aaaa3,*1:*:*:*2:*:*3:*:*:*:*:*:3:*:*:2:*:1 +2313,Polycyclic aromatichydrocarbon (3),a31a(a2a(aa1)aaaa2)aaaa3,*1:*:*:*2:*(:*:1):*:*:*1:*:*:*:*:*:1:2 +2314,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C +2315,Quaternary nitrogen (1),"[s,S,c,C,n,N,o,O]~[nX3+,NX4+](~[s,S,c,C,n,N])~[s,S,c,C,n,N]",*~*(~*)~* +2316,Quaternary nitrogen (2),"[s,S,c,C,n,N,o,O]~[n+,N+](~[s,S,c,C,n,N,o,O])(~[s,S,c,C,n,N,o,O])~[s,S,c,C,n,N,o,O]",*~*(~*)(~*)~* +2317,Quaternary nitrogen (3),[*]=[N+]=[*],*=[N+]=* +2318,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2319,Silicon halogen,"[Si][F,Cl,Br,I]",*[Si] +2320,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1 +2321,Sulfinic acid,"[SX3](=O)[O-,OH]",*S=O +2322,Sulfonic acid,"[C,c]S(=O)(=O)O[C,c]",*OS(*)(=O)=O +2323,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2324,Sulfur oxygen single bond,[SX2]O,OS +2325,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-] +2326,Sulphur nitrogen single bond,[SX2H0][N],NS +2327,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1 +2328,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1 +2329,Thiocarbonyl group,"[C,c]=S",*=S +2330,Thiol (1),[S-],[SH-] +2331,Thiol (2),[SH],[SH] +2332,Three-membered heterocycle,"*1[O,S,N]*1",*1**1 +2333,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2334,Triphenyl methylsilyl,"[SiR0,CR0](c1ccccc1)(c2ccccc2)(c3ccccc3)",c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2335,Triple bond,C#C,C#C +2336,Aromatic NO2,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-c(:*):*",*c(:*):* +2337,Deuterium,[2H],[2HH] +2338,C13,[13#6],[13CH4] +2339,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1 +2340,"Si,B,Se atoms","[Si,B,Se]",* +2341,Hetero imides,[!#6]-[CH2]-N1C(=O)CCC(=O)1,*CN1C(=O)CCC1=O +2342,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O +2343,Acyclic imines,"C-!@[NX2]=[C!R,#1]-C",C*=NC +2344,Alkyl esters of S or P,"[S,P](=O)OC",CO*=O +2345,Ugly P compounds,"P(=[O,S])[C,N]([C,N])[C,N]",**(*)P=* +2346,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN +2347,Acyclic N-C-N,N-!@[CX4]-!@N,NCN +2348,Acyclic N-S,N-!@[SX2]-*,*SN +2349,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O +2350,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O +2351,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1 +2352,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O +2353,Acyl halide,"O=C-[F,Cl,Br,I]",*C=O +2354,Alpha halo carbonyl,"O=C-C-[F,Cl,Br,I]",*CC=O +2355,Sufonyl halide,"S(=O)(=O)-[F,Cl,Br,I]",*[SH](=O)=O +2356,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N +2357,26,N-C(=S)-N,NC(N)=S +2358,Terminal vinyl,[CH2D1]=[CD2]-!@*,*C=C +2359,28,S=P~*,*~P=S +2360,Thio cyanates,S-C#N,N#CS +2361,Thionyl,[Sv4](=O)(-!@[!#1])-!@[!#1],*S(*)=O +2362,N-Haloamines,"N-[F,Cl,Br,I]",*N +2363,N-C-Hal or cyano methyl,"N-C-[F,Cl,Br,I,$(C#N)]",*CN +2364,Alpha beta-unsaturated ketones; center of Michael reactivity,"[$(C#N),$(N(~O)~O),$(C=O),$(S(=O)=O),$(C(F)(F)F),Cl][C!H0]=[C!H0]",*C=C +2365,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O +2366,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2] +2367,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2] +2368,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N +2369,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO +2370,42,S-S,SS +2371,43,O~O,O~O +2372,Aziridine-like N in 3-membered ring,N~1~*~*1,*1~*~N~1 +2373,Aryl iodide,I-c:*,*:cI +2374,Aryl bromide,Br-c:*,*:cBr +2375,Multiple aromatic rings,a1aaa2a(a1)aaa(a2):a,*:*1:*:*:*2:*:*:*:*:*:2:*:1 +2376,S/PO3 groups,"[P,S](~O)(~O)~O",O~*(~O)~O +2377,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3 +2378,Too many cyano groups (>1),C#N.C#N,C#N.C#N +2379,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH] +2380,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O +2381,Chlorates,Cl~O,O~Cl +2382,High halogen content (>3),"[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I]",*.*.*.* +2383,Filter1_2_halo_ether,"[Cl,Br,I][CX4][CX4][$([O,S,N]*),Cl,Br,I]",*CC* +2384,Filter2_acyl_phosphyl_sulfonyl_halide,"[C,S,P](=O)[F,Cl,Br,I]",**=O +2385,Filter3_allyl_halide,"[F,Cl,Br,I][CX4]C=C",*CC=C +2386,Filter4_alpha_halo_carbonyl,"[Br,Cl,I][C!H0]C=[O,S]",*CC=* +2387,Filter5_azo,"[!#7,#1]~[NX2R0]=[NX2R0]~[!#7,#1]",*~N=N~* +2388,Filter6_benzyl_halide,"[Br,Cl,I][CX4]c",*Cc +2389,Filter7_diazo,[!#7]~[NX2]~[NX1],*~N~N +2390,Filter8_thio_isocyanat_diimin,"N=C=[N,O,P,S]",*=C=N +2391,Filter9_metal,"[!#1!#6!#7!#8!#9!#15!#16!#17]~[*,#1]",*~* +2392,Filter10_Terminal_vinyl,"[CH2]=[CH][N,O,P,S;R0]",*[CH]=C +2393,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O +2394,Filter12_nitroso,"[*,#1]~[NX2]~[OX1]",*~N~O +2395,Filter13_PS_double_bond,"S=P~[*,#1]",*~P=S +2396,Filter14_thio_oxopyrylium_salt,"c1ccc[s,o;X2]c1",*1ccccc1 +2397,Filter15_thiosulfate,[SX4](~S)(~O)(~O)~*,*~S(~O)(~O)~S +2398,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C +2399,Filter17_trialkyl_phosphin2,[PX4](~[!O!S])([#6])([#6])[#6],*~P(C)(C)C +2400,Filter18_oxime_ester,"[!#7,#1]C=NO[C,S,P](=O)*",*C=NO*(*)=O +2401,Filter19_hydroxyimide_ester,O=C[NX3](C=O)OC(=O)*,*C(=O)ON(C=O)C=O +2402,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN +2403,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH] +2404,Filter22_sulfonium_salt,*[SX3](*)*,*S(*)* +2405,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O +2406,Filter24_react_imide,"*C([F,Cl,Br,I,$(OS(=O)(=O)*)])=[NX2]*",*N=C(*)* +2407,Filter25_sulfonyl_halide,"*S(=O)(=O)[F,Cl,Br,I]",*S(*)(=O)=O +2408,Filter26_alkyl_halide,"AA[CH2][F,Cl,Br,I,$(OS(=O)(=O)*)]",**[CH2]* +2409,Filter27_anhydride,"*[C,S](=O)O[C,S](=O)*",**(=O)O*(*)=O +2410,Filter28_halo_pyrimidine,"c1nc(ncc1)[Br,I]",*c1ncccn1 +2411,Filter29_thioester,"CC(=[OX1,SX1,NH])[SX2][*,#1]",*SC(=*)C +2412,Filter30_beta_halo_carbonyl,"[#6,#1]C(=O)CC[Br,I]",*CCC(*)=O +2413,Filter31_SO_bond,"[*,#1][SX2R0]O[*,#1]",*OS* +2414,Filter32_OO_bond,"[*,#1][OR0]O[*,#1]",*OO* +2415,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3] +2416,Filter34_isotope,"[2#1,3#1,13C,14C,15N,125I,23F,22Na,32P,33P,35S,45Ca,57Co,103Ru,141Ce]",* +2417,Filter35_PP_bond,P-P,PP +2418,Filter36_SS_double_bond,S=S,S=S +2419,Filter37_silicate,[Si]~O,O~[SiH4] +2420,Filter38_aldehyde,O=[CH]*,*[CH]=O +2421,Filter39_imine,C[CR0]=[NR0][*!O],*N=CC +2422,Filter40_epoxide_aziridine,"C1C[N,S,O]1",*1CC1 +2423,Filter41_12_dicarbonyl,*C(=O)C(=O)*,*C(=O)C(*)=O +2424,Filter42_12_dicarbonyl_tautomer,[*!$(C[OH])]=C([OH])C(=O)*,*C(=O)C(=*)[OH] +2425,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O +2426,Filter44_michael_acceptor2,"[#6,#1,OH0][C!$(C1(=O)C=CC(=O)C=C1)](=O)C=[C!$(C[Nv3X3,OH])]",*C(=O)C=C +2427,Filter45_allyl_halide2,"[Br,Cl,I][CX4]C=[C,N,P]",*CC=* +2428,Filter46_nhalide,"N[F,Cl,Br,I]",*N +2429,Filter47_SO2F,O=S(=O)(*)F,*S(=O)(=O)F +2430,Filter48_FOSO,O=S(*)OF,*S(=O)OF +2431,Filter49_halogen,"[*,#1]~[F,Cl,Br,I]~[*,#1]",*~*~* +2432,Filter50_grignard,"C[Mg][F,Cl,Br,I]",*[Mg]C +2433,Filter51_PN3,N[PX3](N)N,NP(N)N +2434,Filter52_NC_haloamine,"NC[F,Cl,Br,I]",*CN +2435,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +2436,Filter56_SS_bond,S-S,SS +2437,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1 +2438,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1 +2439,Filter59_phoshorous_ylide,C=P,C=P +2440,Filter60_Acyclic_N-S,N!@[SX2],N~S +2441,Filter61_phosphor_halide_and_P_S_bond,"[#15]~[F,Cl,Br,I,#16]",*~P +2442,Filter62_oxo_thio_halide,"[O,S]~[Cl,Br,I]",*~* +2443,Filter63_polyaromatic,a1aaaa2ccc3ccccc3c12,*1:*:*c2*(:*:1)ccc1ccccc12 +2444,Filter64_halo_ketone_sulfone,"[#6][C,S](=[O,S])C[F,Cl,Br,I]",*C*(=*)C +2445,Filter65_alkyl_sulfonate,"[#6][P,S](~[OX1])(~[OX1])O[C!H0]",CO*(C)(~O)~O +2446,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F +2447,Filter67_S_or_O_C_triplebond_N,"[O,S]C#N",*C#N +2448,Filter68_anthracene_acridine,a1aaac2cc3ccccc3cc12,*1:*:*c2cc3ccccc3cc2*:1 +2449,Filter69_thio_carbonate,"[O,S]C(=[O,S])[O,S]",*C(*)=* +2450,Filter70_AlkylCN2,*(C#N)C#N,N#C*C#N +2451,Filter71_thio_anhydride,"*C(=[O,S])[O,S]C(=[O,S])*",*C(=*)*C(*)=* +2452,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH] +2453,Filter73_thio_ketone,CC(=S)C,CC(C)=S +2454,Filter74_thiol,*[SX2H],*[SH] +2455,Filter75_alkyl_Br_I,"[C!H0][Br,I]",*C +2456,Filter76_S_ester,CC(=S)O,CC(O)=S +2457,Filter77_alkyl_NO2,"[*!#7]~[#6]-,=CN(~O)(~O)",*~CCN(~O)~O +2458,Filter78_bicyclic_Imide,*~@C1C(=O)NC(=O)C(~@*)1,*~C1C(~*)C(=O)NC1=O +2459,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1 +2460,Filter80_Thioepoxide_aziridone,"[N,S]1[C,N,S][C,N,S]1",*1**1 +2461,Filter81_Thiocarbamate,"S!@C(=!@[O,S])!@[#7]",*=C(~N)~S +2462,Filter82_pyridinium,"[c,n]1[c,n][c,n][c,n][c,n]n(C)1",Cn1*:*:*:*:*1 +2463,Filter83_per_halo_chain,"[F,Cl,Br,I]C-,=;!@C([F,Cl,Br,I])-,=;!@C([F,Cl,Br,I])",*CC(*)C* +2464,Filter84_nitrogen_mustard,"[N,P,Se,S][C!H0]C[Br,Cl,I]",*CC* +2465,Filter85_keto_acrylonitrile,*C(=O)C(=!@[C!H0])C#N,*C(=O)C(=C)C#N +2466,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N +2467,Filter87_crowns,"[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[O,N]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@C",*C~C*C~C*C~C*C +2468,Filter88_ene_sulfone,[C!H0]=CS(=O)(=O)*,*S(=O)(=O)C=C +2469,Filter89_hydroxylamine,"[*!$(C=O)]!@N!@O[*,#1]",*~N~O* +2470,Filter90_N_double_bond_S,N=!@S,N=S +2471,Filter92_trityl,*(c1ccccc1)(c1ccccc1)(c1ccccc1),c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2472,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O +2473,Filter94_2_halo_pyridine,"c1nc(ccc1)[Br,I,Cl,F]",*c1ccccn1 +2474,Anhydride,C(=O)OC(=O),O=COC=O +2475,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1 +2476,Any carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2477,HOBT ester,C(=O)Onnn,nnnOC=O +2478,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-] +2479,Imine2,"[#6,#8,#16]-[CH1]=[NH1]",*C=N +2480,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N +2481,Cyanohydrin,N#CC[OH],N#CC[OH] +2482,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl +2483,P/S halide,"[P,S][F,Cl,Br,I]",** +2484,Quaternary,"[C+,Cl+,I+,P+,S+]",* +2485,Unacceptable atoms,[!#6;!#7;!#8;!#16;!#1;!#3;!#9;!#11;!#12;!#15;!#17;!#19;!#20;!#30;!#35],* +2486,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2487,b-Carbonyl quaternary nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2488,Benzylic quaternary nitrogen,cC[N+],cC[N+] +2489,Phosphorane,C=P,C=P +2490,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S +2491,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2492,Sulfonate,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2493,Heteroaryl sulfonate,"a-S(=O)(=O)-O[$([a&!#6]),$(c[a&!#6]),$(cc[a&!#6]),$(ccc[a&!#6]),$(cccc[a&!#6]),$(ccccc[a&!#6])]",*OS(*)(=O)=O +2494,Sulfate ester,"COS(=O)O[C,c]",*OS(=O)OC +2495,Polyacidic,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2496,Thiol,[SH],[SH] +2497,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1 +2498,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +2499,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2500,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2501,Allene,*=C=*,*=C=* +2502,Azide,"[$(*-[NX2-]-[NX2+]#[NX1]),$(*-[NX2]=[NX2+]=[NX1-]),$(N=N=N)]",* +2503,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O +2504,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2505,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH] +2506,Ester,[#6]-C(=O)O-[#6],COC(C)=O +2507,Imine 1,"[#6,#8,#16]-C(=[NH1])[#6,#8,#16]",*C(*)=N +2508,Imine 3,C=[NH],C=N +2509,Thioketone,CC(=S)C,CC(C)=S +2510,Thionoester,COC(=S)C,COC(C)=S +2511,Thioamide,CC(=S)N,CC(N)=S +2512,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC +2513,Long aliphatic chain,"[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]",******* +2514,Unbranched chain,"[$([A&D2]),$([A&D1])]!@[A&D2]!@[A&D2]!@[A&D2]!@[A&D2]!@[$([A&D2]),$([A&D1])]",*~*~*~*~*~* +2515,Dye 25,acC=&!@Cca,*cC=Cc* +2516,Isonitrile,[N+]#[C-],[C-]#[NH+] +2517,Thiocyanate,SC#N,N#CS +2518,Dye 16 (1),"c[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c +2519,Nitro aromatic 2+,"a-[$([NX3](=O)=O),$([NX3+](=O)[O-])].a-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",**.** +2520,Dye 29,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-caac-[$(N(C)C),$([NH]C),$([NH2])]",*c*:*c* +2521,Dye 1 (1),"c1cccc(C(=O)[C,c]([#7])=,:[C,c]([#7])C2(=O))c12",N*1=*(N)C(=O)c2ccccc2C1=O +2522,Dye 7,"N=C1[#6]:,=[#6]C(=[C,N])[#6]:,=[#6]1",*=C1C:CC(=N)C:C1 +2523,Dye 11,"*=,:[#6]C([#6]=,:*)[#6]=,:*",*=CC(C=*)C=* +2524,Dye 9,ac-*=&!@*-&!@C(=O)-&!@ca,*c*=*C(=O)c* +2525,Dye 32,"c1cccc2C(=O)C(C:,=*)C(=O)c12",*:CC1C(=O)c2ccccc2C1=O +2526,Dye 6,c12cccc(C(=O)C(ca)C(=O)3)c2c3ccc1,*cC1C(=O)c2cccc3cccc(c23)C1=O +2527,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1 +2528,Dye 2,OCccCO,OCccCO +2529,Dye 26,c1ccccc1-n2nnnc2[CH2]*,*[CH2]c1nnnn1-c1ccccc1 +2530,Perhalo_ketone,"O=CC(-[F,Cl,Br,I])([F,Cl,Br,I])-[F,Cl,Br,I]",*C(*)(*)C=O +2531,Beta halo carbonyl,"O=CCC[F,Cl,Br,I]",*CCC=O +2532,4-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[n]:[c,n]:[c,n]1",*c1*:*n*:*1 +2533,2-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[c,n]:[c,n]:[n]1",*c1*:*:*:*n1 +2534,Hetero_hetero,"*[N,S,O]-&!@[N,S,O][#6]",***C +2535,Disulfide,SS,SS +2536,Vinyl michael acceptor1,"[#6]-[CH1]=C-C(=O)[#6,#7,#8]",*C(=O)C=CC +2537,Vinyl michael acceptor2,"[CH2]=C-C(=O)[#6,#7,#8]",*C(=O)C=C +2538,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N +2539,Michael acceptor 6,"[#6,#7]-&!@[#6](=&!@[CH])-&!@C(=O)-&!@[C,N,O,S]",*C(=[CH])C(*)=O +2540,Alkynyl michael acceptor1,"[#6]-C#CC(=O)[#6,#7,#8]",*C(=O)C#CC +2541,Alkynyl michael acceptor2,"[CH1]#CC(=O)-[#6,#7,#8]",*C(=O)C#C +2542,Nitroalkane,"C[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*C +2543,Nitrate,"[#6]-O-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*OC +2544,Oxalyl,O=C-&!@C=O,O=CC=O +2545,Dipeptide,*-C(=O)-&!@[NH]-C-&!@C(=O)-&!@[NH]-*,*NC(=O)CNC(*)=O +2546,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-] +2547,Triphenylphosphine,a-P(-a)-a,*P(*)* +2548,Phosphoric acid,[OH]-P(=O)(-O)-*,*P(=O)(O)O +2549,Phosphoric ester,COP(=O)(-*)O,*P(O)(=O)OC +2550,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2551,Tri phosphoric esters,[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6],*P(=O)(OC)OC.*P(=O)(OC)OC.*P(=O)(OC)OC +2552,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O +2553,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12 +2554,Poly(azo(anthracene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1[c,n]c3:[c,n]:[c,n]:[c,n]:[c,n]:c3[c,n]2",*1:*:*c2*c3*:*:*:*c3*c2*:1 +2555,Poly(azo(phenanthrene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1:[c,n]:[c,n]:c3:[c,n]:[c,n]:[c,n]:[c,n]:c23",*1:*:*c2c(*:1)*:*c1*:*:*:*c12 +2556,Dye 31,a1aaac2ac3acac4aaac(c34)c12,*1:*:*c2c(*:1)*c1*c*c3*:*:*c2c31 +2557,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21 +2558,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O +2559,"Epoxide, aziridine, thioepoxide","C1[O,S,N]C1",*1CC1 +2560,Propiolactone,C1(=O)OCC1,O=C1CCO1 +2561,b-Lactam,N1CCC1=O,O=C1CCN1 +2562,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2563,Aromatic sulfonic ester,"[#6,#7]-S(=O)(=O)Oc",*S(=O)(=O)Oc +2564,Quinone,"[$([o,n]=c1ccc(=[o,n])cc1),$([O,N]=C1C=CC(=[O,N])C=C1),$([O,N]=C1[#6]:,=[#6]C(=[O,N])[#6]:,=[#6]1)]",* +2565,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2566,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2567,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2568,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1 +2569,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2570,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1 +2571,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2572,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2573,Acid_anhydrides,C(=O)OC(=O),O=COC=O +2574,Acid_halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2575,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1 +2576,Active_phosphate,"P(=S)([OH1,O$(O[#6])])([OH1,O$(O[#6])])[S,O]",*P(*)(*)=S +2577,Acyl_cyanide,C(=O)-C#N,N#CC=O +2578,Adjacent_ring_double_bonds,[*;R]=[*;R]=[*;R],*=*=* +2579,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F +2580,Alkyl_halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2581,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C +2582,Alpha_halo_carbonyl,"[C;!$(C[N])](=O)!@[C;h1,h2;H1,H2][F,Cl,Br,I]",*C~C=O +2583,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O +2584,Aminonitrile,NC#N,NC#N +2585,Any_carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2586,Aromatic_azides,"c[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*c +2587,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-] +2588,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2589,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1 +2590,B-carbonyl_quaternary_nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2591,Benzylic_quaternary_nitrogen,"cC[N+,NX4]",*Cc +2592,Beta-carbonyl_quaternary_nitrogen,"C(=O)C[N+,n+,NX4,nX4]",*CC=O +2593,Beta-fluoro-ethyl-on,"[C;H2$(CF),H1$(C(F)F)]!@[CH2][N,O]",*[CH2]~C +2594,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2595,Carbazides,"C(=O)[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*C=O +2596,CCl3-CHO_releasing,"C(Cl)(Cl)(Cl)C([O,S])[NX3]",*C(N)C(Cl)(Cl)Cl +2597,Conjugated_dithioether,SC(=[!r])S,*=C(S)S +2598,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1 +2599,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1 +2600,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1 +2601,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2602,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2603,Diacetylene,C#CC#C,C#CC#C +2604,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-] +2605,Diazonium_salt,[N+]#N,N#[NH+] +2606,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O +2607,Dinitrobenzene_1,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc1",*c1ccccc1* +2608,Dinitrobenzene_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])c1",*c1ccc(*)cc1 +2609,Dinitrobenzene_3,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1cccc(*)c1 +2610,Dithiocarbamate,NC(=S)S,NC(S)=S +2611,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1 +2612,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1 +2613,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS +2614,Enyne,C=!@CC#C,C#CC=C +2615,"Epoxides,_thioepoxides,_aziridines","C1[O,S,N]C1",*1CC1 +2616,Ester_of_HOBT,C(=O)Onnn,nnnOC=O +2617,Flavin,"c1cccc(NC(=NC(=[N,S,O])NC(=O)3)C3=N2)c12",*=C1NC(=O)C2=Nc3ccccc3NC2=N1 +2618,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2 +2619,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF +2620,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F +2621,Four_member_lactones,C1(=O)OCC1,O=C1CCO1 +2622,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN +2623,Geminal_dinitriles,N#CCC#N,N#CCC#N +2624,"Halo-pyridine, -diazoles and -triazoles","[Cl,Br,I]c1[c,n][c,n][c,n][c,n]n1",*c1*:*:*:*n1 +2625,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1 +2626,Imines_(not_ring),"[#6][CR0](=[NR0,OR0])[#6]",*=C(C)C +2627,Isocyanates_and_isothiocyanates,"N=C=[S,O]",*=C=N +2628,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S +2629,Michael_phenyl_ketone,c1ccccc1C(=O)C=!@CC(=O)!@*,*~C(=O)C=CC(=O)c1ccccc1 +2630,Nitrobenz-azadiazole_1,"c1ccc(n[o,s]n2)c2c1[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c1cccc2n*nc12 +2631,Nitrobenz-azadiazole_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc(n[o,s]n2)c2c1",*c1ccc2n*nc2c1 +2632,Nitrosamine,N-[N;X2](=O),NN=O +2633,Noname,"N1=C[S,NH1]C(=[C,N,P][C,N,O,P])C1(=O)",**=C1*C=NC1=O +2634,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-] +2635,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN +2636,Orthoester,C(O)(O)[OH],OC(O)[OH] +2637,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH] +2638,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1 +2639,P_or_S_halides,"[P,S][Cl,Br,F,I]",** +2640,P-aminoaryl_diazo,Nc1aaa(N!@=N)aa1,Nc1*:*:*(N~N):*:*1 +2641,PCP,PCP,PCP +2642,Paranitrophenyl_esters,"C(=O)Oc1ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1ccc(OC=O)cc1 +2643,Pentahalophenyl,"c1c([F,Cl])c([F,Cl])c([F,Cl])c([F,Cl])c1([F,Cl])",*c1cc(*)c(*)c(*)c1* +2644,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2645,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34 +2646,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1 +2647,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O +2648,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2649,Phosphorus_halide,"[S,P][F,Cl,Br,I]",** +2650,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2651,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc +2652,Polyines,CC#CC#CC,CC#CC#CC +2653,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1 +2654,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12 +2655,Polysulfide,*[SX2][SX2][SX2]*,*SSS* +2656,Sulphur_halide,"[#16][F,Cl,Br,I]",*S +2657,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34 +2658,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1 +2659,Reactive_carbonyls,"[C;!r](=[O,S])[S;!r]",*=CS +2660,Ring_triple_bond,"[C,c;R]#[C,c;R]",*#* +2661,S=N (not_ring),[S;R0]=[N;R0],N=S +2662,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O +2663,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2664,Sulphate_ester,"COS(=O)O[C,c]",*OS(=O)OC +2665,Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2666,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S +2667,Tetraazinane,C1NNC=NN1,C1NNC=NN1 +2668,Thioles_(not_aromatic),[!a][SX2;H1],*S +2669,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S +2670,Three_membered_heterocycle,"*1[O,S]*1",*1**1 +2671,Tri_pentavalent_S,"[#16v3,#16v5]",* +2672,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1 +2673,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1 +2674,Triphenylphosphines,P(c1aaaaa1)(c1aaaaa1)(c1aaaaa1),*1:*:*c(P(c2*:*:*:*:*2)c2*:*:*:*:*2)*:*:1 +2675,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1 +2676,Vinyl_halide,"[Cl,Br,I]C=[!O!R]",*C=* +2677,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O +2678,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O +2679,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1 +2680,Oxime,"[#6]C(=!@N[$(OC),$([OH])])[#6]",*N=C(C)C +2681,Hydrazone,[#6]C(=!@NNa)[#6],*NN=C(C)C +2682,Nitrosone_not_nitro,[$(N(~!@[#6])!@O);!$([N+]([O-])=O)],* +2683,Thiocarbonyl_group,C=S,C=S +2684,Enamine_like,C=[NH],C=N +2685,Analine,"c1ccccc1[NH2,NH3+]",*c1ccccc1 +2686,Acid_anhydrides_2,"[#6]C(=O)!@OC(=!@[N,O])[#6]",*=C(C)O~C(C)=O +2687,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F +2688,Triple_bond,[#6]C#[CH],CC#C +2689,Thiatetrazolidine,"[$(Sc1nnn[nH,n-]1),$(Sc1nn[nH,n-]n1)]",* +2690,Glycol,"[#6][O;R0][$(C([#6])[#6]),$([CH][#6]),$([CH2])][O;R0][#6]",CO*OC +2691,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O +2692,Formate_formide,"O=[CH][O,N][#6]",C*[CH]=O +2693,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1 +2694,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1 +2695,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1 +2696,Thiazolidinone,O=C1CSCN1,O=C1CSCN1 +2697,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1 +2698,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1 +2699,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1 +2700,Ethene,C=[CH2],C=C +2701,Cyclobutene,C1CC=C1,C1CC=C1 +2702,Poly_sub_atomatic,*!@c1c(!@*)c(!@*)c(!@*)c(!@*)c1,*~c1cc(~*)c(~*)c(~*)c1~* +2703,Isotopes,"[2#1,3#1,11C,11c,14C,14c,125I,32P,33P,35S]",* +2704,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C +2705,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-] +2706,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-] +2707,Sulphur atom (1),[SX2H1],[SH] +2708,Sulphur atom (2),"[$([SX2H0]);!$([S][#6X3,#7X2]);!$([S][CX4H0])]",* +2709,Sulphur atom (3),"[$([SX2H0][#6X3,#7X2]);!$([S](~[#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2710,Sulphur atom (4),[$([S][*D4H0]);$([SX2H0])],* +2711,Sulphur atom (5),"[$([SX2H0]([#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2712,Sulphur atom (6),[sX2r5],s +2713,Sulphur atom (7),[$([#16X3](=[OX1]));$([#16]);!$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2714,Sulphur atom (8),[$([#16X3](=[OX1]));$([#16]);$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2715,Aldehyde carbon atoms,[$([CX3H1](=O)[#6])],* +2716,Phosphor with double bonded sulphur,[$([PX4]);$([P]=[S])],* +2717,sp3 hybridized carbon atoms (1),[$([CX4]([#6X3])([#6X3])[#6X3]);!$([CH0])],* +2718,sp3 hybridized carbon atoms (2),"[$([CX4][N]);!$([CH0]);!$([C][N]([#6X3,#7X2])[#6X3,#7X2]);!$([C][N]=[#6X3]);!$([CX4][NX3][C]=[O])]",* +2719,sp3 hybridized carbon atoms (3),"[!$([CH0]);$([CX4]([#6X3])[#6X3]),$([CX4][#7]=[#6X3]),$([CX4]([#8])[#8]);!$([CX4]([#8])[#8][C]=[O])]",* +2720,sp3 hybridized carbon atoms (4),[$([CX4][S]);!$([CH0]);!$([C][S]=[O])],* +2721,sp3 hybridized carbon atoms (5),"[$([CX4][#6X3]~[#8]),$([CX4][#6X3](~[#7])~[#7]),$([CX4][#6X2]),$([CX4][CX3]=[CX3]-[#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3]);!$([CX4][#6X3](=[#8])-[#8]);!$([CX4][CX3]([CX3])=[CX3]-[#6X3])]",* +2722,sp3 hybridized carbon atoms (6),[$([CX4][O]);!$([CH0]);!$([C][O][C]=[O]);!$([CX4]1[O][C]1)],* +2723,sp3 hybridized carbon atoms (7),[$([CX4][#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3])],* +2724,sp3 hybridized carbon atoms (8),"[$([CX4][#7](~[#6X3,#7X2])~[#6X3,#7X2]);!$([CH0])]",* +2725,sp3 hybridized carbon atoms (9),[$([CX4][S](=[O])=[O]);!$([CH0])],* +2726,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C +2727,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C +2728,sp3 hybridized carbon atoms (12),[$([CX4][NX3H1][C]=[O]);!$([CH0])],* +2729,sp2 hybridized carbon atoms (1),"[$([CX3H2]);$([C]=[#6X3,#7X2]-[#6X3,#7X2])]",* +2730,sp2 hybridized carbon atoms (2),"[$([CX3H1]);$([C]=[#6X3,#7X2]-[#6X3,#7X2]);!$([C](-[#6X3,#7X2])=[#6X3,#7X2]-[#6X3,#7X2])]",* +2731,sp2 hybridized carbon atoms (3),[$([cH1]);$([c](:[#7]):[#7])],* +2732,sp2 hybridized carbon atoms (4),"[$([ch1]);!$([ch1]1:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]:[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]1);$([ch1]1:[c](-[NX3]):[c]:[c]:[c]:[c]1),$([c]1:[c]:[c]:[c](-[NX3]):[c]:[c]1)]",* +2733,sp2 hybridized carbon atoms (5),"[$([CX3]);$([CX3]=[CX3]);!$([CH0]);!$([CX3](-[#6X3,#7X2])=[CX3]);!$([CX3]=[CX3]-[#6X3,#7X2])]",* +2734,sp2 hybridized carbon atoms (6),[$([cH1]);$([c]:[#16])],* +2735,sp2 hybridized carbon atoms (7),"[$([ch1]);$([c]1:[c]:[c]:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]1),$([c]1:[c]:[c]:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1)]",* +2736,sp2 hybridized carbon atoms (8),"[$([ch1]);!$([c]1:[c]:[c]:[c](-[O]-[C]=[O]):[c]:[c]1);$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1),$([c]1:[c]:[c]:[c](-[O,SX2]):[c]:[c]1)]",* +2737,sp2 hybridized carbon atoms (9),[$([cH1]);$([c]1:[c]:[#16]:[c]:[c]1)],* +2738,sp2 hybridized carbon atoms (10),"[$([ch1]);$([ch1]1:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]1:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]:[c]-[O,SX2]);!$([ch1]:[c]-[O]-[C]=[O])]",* +2739,sp2 hybridized carbon atoms (11),"[$([CX3H1,cX3H1]);!$([ch1]1:[c]:[c]:[#7]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]1);!$([ch1]:[#7])]",* +2740,sp2 hybridized carbon atoms (12),"[$([ch1]1:[c]:[c]:[#7]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]1),$([ch1]:[#7])]",* +2741,Nitrogen atoms (1),"[$([NX3H0]);!$([NX3][#6X3,#7X2])]",* +2742,Nitrogen atoms (2),"[$([NX3]);$([H1,H2])]",* +2743,Nitrogen atoms (3),[$([N]([#6X3]1)[#6X3]=[#6X3][#6X4][#6X3]=1)],* +2744,Nitrogen atoms (4),"[$([NX3H0]);$([NX3][#6X3,#7X2]);!$([NX3]([#6X3,#7X2])[#6X3,#7X2])]",* +2745,Nitrogen atoms (5),"[$([nr6]),$([NX2]=[C])]",* +2746,Nitrogen atoms (6),"[$([N]);$([NX3H0]([#6X3,#7X2])[#6X3,#7X2]),$([NX2H1][C]=[O])]",* +2747,Nitrogen atoms (7),[nr5H0],n +2748,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21 +2749,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C +2750,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1 +2751,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1 +2752,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1 +2753,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1 +2754,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1 +2755,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1 +2756,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1 +2757,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1 +2758,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1 +2759,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1 +2760,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1 +2761,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2 +2762,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC +2763,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1 +2764,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1 +2765,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1 +2766,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1 +2767,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1 +2768,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1 +2769,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1 +2770,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1 +2771,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1 +2772,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12 +2773,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1 +2774,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1 +2775,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1 +2776,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1 +2777,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1 +2778,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1 +2779,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2 +2780,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2 +2781,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1 +2782,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2 +2783,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +2784,4-chlorobenzene,Clc1ccc([*:1])cc1,Clc1ccc([*:1])cc1 +2785,4-nitrobenzene,[O-][N+](=O)c1cc([*:1])c([*:1])cc1,O=[N+]([O-])c1ccc([*:1])c([*:1])c1 diff --git a/E_coli activity prediction model/Functional_groups_filtered.csv b/E_coli activity prediction model/Functional_groups_filtered.csv new file mode 100644 index 0000000000000000000000000000000000000000..7cf7df83bf69ecbcae356b16681926e9921a4155 --- /dev/null +++ b/E_coli activity prediction model/Functional_groups_filtered.csv @@ -0,0 +1,2787 @@ +,index,Functional grp name,SMARTS +0,0,Acid halides,"[F,Cl,Br][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]" +1,1,Acid azides,"[CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]" +2,2,Sulphonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[Cl,Br]" +3,3,Sulphonyl azides,"[Sv6X4](=[OX1])(=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]" +4,4,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]) +5,5,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]) +6,6,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1 +7,7,Isocyanates,[NX2]=[CX2]=[OX1] +8,9,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]) +9,10,Thioesters,[CX3](=[SX1])[SX2] +10,11,Haloalkanes,"[CX4][Cl,Br,I]" +11,12,Dialkylsulfates/ sulfonates,"[$([#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6]),$([#6][Sv6X4](=[OX1])(=[OX1])[OX2][#6])]" +12,13,N-Trihalomethyl imides,"[CX3](=[OX1])[NX3]([CX4]([Cl,Br,I])([Cl,Br,I])[Cl,Br,I])[CX3](=[OX1])" +13,15,Quinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]" +14,16,Hydroquinones and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1][cR1][cR1]([OX2][#1,CX4])[cR1][cR1]1" +15,17,Catechols and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1]([OX2][#1,CX4])[cR1][cR1][cR1][cR1]1" +16,18,"α, β-Unsaturated aldehydes, amides, esters and ketones","[$([CX3]([#6,$([NX3]([CX3]=[OX1])([#6])[#6]),$([OX2]([CX3]=[OX1])[#6]);!$([OH][CX3]=[OX1]);!$([O-][CX3]=[OX1])])(=[OX1])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX3H1](=[OX1])[CX3]([#6,#1])=[CX3])]" +17,19,"Precursors of α, β-unsaturated aldehydes, amides, esters and ketones (1)","[$([CX4]([OX2])([OX2])([#6,#7,#8])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX4H1]([OX2])([OX2])[CX3]([#6,#1])=[CX3])]" +18,21,"1,3-Diketones","[CX4,a!r0][CX3](=[OX1])[CH2][CX3](=[OX1])[CX4,a!r0]" +19,22,Aldehydes,"[CX3]([H])(=[OX1])[#1,CX4,a!r0]" +20,23,Ketones,"[CX4,a!r0][CX3](=[OX1])[CX4,a!r0]" +21,24,Formaldehyde donors,"[$([NX3][CH2][NX3]),$([NX3][CH2][OX2]),$([CX4]([F,Cl,Br,I])([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])[CH2][OH1])]" +22,25,Precursors of aldehydes and ketones,"[CX4]([OX2])([OX2])([CX4,a!r0])[CX4,a!r0]" +23,26,Enol precursor of aldehydes and ketones,"[CX3]=[CX3]([#6,#1])[OX2]" +24,27,Aromatic primary and secondary amines,"[a!r0][$([NX3H2]),$([NX3H1][CX4,a!r0])]" +25,28,N-Haloimides,"[CX3](=[OX1])[NX3]([Cl,Br])[CX3](=[OX1])" +26,29,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl +27,30,Disullides,"[CX4,a!r0][SX2][SX2][CX4,a!r0]" +28,31,Phenyl carbonates,"c1ccccc1[OX2][CX3](=[OX1])[OX2][CX4,a!r0]" +29,32,Epoxides,[CX4]1[CX4][OX2]1 +30,33,1.2-Dicarbonyls,"[CX4,a!r0][CX3](=[OX1])[CX3](=[OX1])[#1,CX4,a!r0]" +31,34,Thiazolones,"[$([SX2]1[CX3]([CX4,a!r0])=[CX3]([CX4,a!r0])[CX3](=[OX1])[NX3]1([CX4,a!r0])),$([sX2]1[cX3]([CX4,a!r0])[cX3]([CX4,a!r0])[cX3](=[OX1])[nX3]1([CX4,a!r0]))]" +32,35,"1, 2-Diamines","[CX4,a!r0][NX3H1][CX4][CX4][NX3H1][CX4,a!r0]" +33,37,Quaternary ammonium cation,"[NX4+]([CX4,a!r0])([CX4,a!r0])([CX4,a!r0])[CX4,a!r0]" +34,38,Activated N-heterocycle halides,"[$(n1c([F,Cl])ncnc1),$(n1c([F,Cl])ccnc1),$(n1c([F,Cl])nccc1)]" +35,44,Aromatic sulphuric acids and salts,"[a!r0][Sv4X3](=[OX1])[$([OH]),$([O-])]" +36,46,Iso(thio)cyanates,"[NX2]=[CX2]=[OX1,SX1]" +37,50,Acid imides,"[NX3]1([#1,#6])[CX3](=[OX1])[CX3]([!R])=[CX3]([!R])[CX3]1(=[OX1])" +38,53,Activated N-heterocycles,"[$(n1c([F,Cl,$([CX2]#[NX1])])nccc1),$(n1cnccc1([F,Cl,$([CX2]#[NX1])])),$(n1cncnc1([F,Cl,$([CX2]#[NX1])]))]" +39,59,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4] +40,60,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4] +41,65,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]) +42,68,Aldehydes and precursors,"[$([#1,#6;!$(C=C);!$(C#C)][CX3]([H])(=[OX1])),$([CX4;H1]([OX2])[OX2])]" +43,70,"α, β-Unsaturated carbonyls","[CX3]=[CX3][CX3](=[OX1])[$([OX2]([CX3]=[OX1])[!#1]),$([#1][CX3]=[OX1]),$([NX3H2]([CX3]=[OX1])),$([NX3]([CX3]=[OX1])),$([CX4][CX3]=[OX1])]" +44,71,Hydroquinones,[OH1]c1ccc([OH1])cc1 +45,72,Catechols,[OH1]c1c([OH1])cccc1 +46,73,Resorcinols,[OH1]c1cc([OH1])ccc1 +47,74,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1 +48,75,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1 +49,76,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1 +50,78,Thiols,[#16X2H1] +51,79,Disulfides,*[#16X2][#16X2]* +52,82,Diaryl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[a!r0] +53,83,Arylacyl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[A] +54,84,Haloamides,"[#6][CX3](=[OX1])[NX3]([F,Cl,Br,I])[#6]" +55,85,Hydroperoxides and precursors,[#6][OX2][OX2][OH1] +56,86,"1,2-Dihydroxy aromatic compounds",[OH1]aa[OH1] +57,87,"1,4-Dihydroxy aromatic compounds",[OH1]aaaa[OH1] +58,88,2 or 4-Hydroxysubstituted alkylphenyl ether,"[$(c1c([OX2][CX4])c([OH1])ccc1),$(c1c([OX2][CX4])ccc([OH1])c1)]" +59,89,Aromatic amines,"[a!r0][$([NX3H2]),$([NX3H1][#6])]" +60,90,Aromatic amines precursors,"[$([a!r0][NH1][CX3](=[OX1])),$(c1c([NX2]=[NX2][a!r0])ccc([$([NX3]([CX4])([CX4])),$([NX3H1][CX4]),$([NH2]),$([OH1])])c1)]" +61,91,Alkyl or aryl sylfonyl halides,"[CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]" +62,92,Sulfonamides,"c1c([Sv6X4](=[OX1])(=[OX1])[NX3H1][$([#1]),$([CX4]),$([a!r0])])ccc([NX3H2])c1" +63,95,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3] +64,96,Hydrazines,"[#6&!$([CX3]=[OX1,SX1,NX2])][NX3H1][NX3H2,$([NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])])]" +65,98,Aromatic nitro (general),"[a!r0][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]" +66,99,Aromatic amine (general),[a!r0][NX3H2] +67,100,Three-membered heterocycles (general),"[NX3H1,SX2,OX2]1[CX4][CX4]1" +68,101,Nitroso (general),[NX2]=[OX1] +69,102,Unsubstituted heteroatom-bonded heteroatom (general),"[$([NX3H2]-[#7]),$([NX3H2]-[#8]),$([OX2H1]-[#7]),$([OX2H1]-[#8])]" +70,103,Azo-type (general),[NX2]=[NX2] +71,104,Aliphatic halide (general),"[CX4][Cl,Br,I]" +72,105,Polycyclic aromatic system (general),"[$([aR3]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))])]" +73,108,Aromatic nitroso (specific),[a!r0][NX2]=[OX1] +74,109,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4] +75,110,Nitrosamine (specific),"[OX1]=[NX2][NX3]([#6,#1])[#6,#1]" +76,111,Epoxide (specific),[CX4]1[OX2][CX4]1 +77,112,Aziridine (specific),[CX4]1[NX3H1][CX4]1 +78,113,Azide (specific),"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]" +79,114,Diazo (specific),"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]" +80,115,Triazene (specific),[NX3!R][NX2!R]=[NX2!R] +81,118,Aromatic hydroxylamine (specific),[a!r0][NX3H1][OH1] +82,119,Aliphatic halide (specific),"[Cl,Br,I][$([CX4]);!$([CX3](=[OX1,SX1,NX2]));!$([CH2][CH2][SX2,NX3])]" +83,120,Carboxylic acid halide (specific),"[Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]" +84,121,Nitrogen and sulphur mustard (specific),"[Cl,Br,I][CH2][CH2][SX2,NX3]" +85,123,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3 +86,124,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3 +87,125,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2] +88,126,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1] +89,127,Aliphatic N-nitro (additional),"[NX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1][O-]))]" +90,128,Diazonium (additional),"[$([a!r0][NX2+]#[NX1]),$([a!r0][NX2]#[NX1])]" +91,129,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]) +92,130,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1] +93,131,1-Aryl-2-monoalkyl hydrazine (additional),[a!r0][NX3H1]-[NX3H1][CX4] +94,132,Aromatic methylamine (additional),[a!r0][NX3;H1][CH3] +95,133,Aromatic hydroxylamine ester (additional),[a!r0][NH][OX2][CX3](=[OX1]) +96,134,Polycyclic planar system (additional),[*R1]1[*R2]2=[*R1][*R1]=[*R1][*R1]=[*R2]2[*R1][*R2]3=[*R1][*R1]=[*R1][*R1]=[*R2]13 +97,135,Acyl halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]" +98,137,N-Methylol derivatives,[OX2;H1][CH2][NX3] +99,138,Monohaloalkene,"[CX3]([CX4,#1])([F,Cl,Br,I])=[CX3]([CX4,#1])[!F!Cl!Br!I]" +100,139,S or N mustard,"[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]" +101,140,Propiolactones or propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]" +102,141,Epoxides and aziridines,"[CX4]1[OX2,NX3][CX4]1" +103,142,Aliphatic halogens,"[CX4;!H0][Br,Cl,I]" +104,143,Alkyl nitrite,[OX1]=[NX2][OX2][CX4] +105,145,Simple aldehyde,"[CX3]([H])(=[OX1])[#1,#6&!$([CX3]=[CX3])]" +106,147,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])] +107,148,Aliphatic azo and azoxy,"[$([C,#1][NX2]=[NX2][C,#1]),$([CX3]=[NX2+]=N),$([CX3]=[NX2+]=[NX1-]),$([CX3-][NX2+]#[NX1]),$([CX3][NX2]#[NX1]),$(C[NX2]=N(=O)[*]),$(C[NX2]=[N+]([O-])[*])]" +108,149,Isocyanate and isothiocyanate groups,"[NX2]=[CX2]=[OX1,Sv2X1]" +109,150,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C" +110,151,Thiocarbonyl,"[$([NX3][CX3](=[Sv2X1])[NX3]),$([CX3;!$(C[OH]);!$(C[SH]);!$(C[O-]);!$(C[S-]);!$(CO[#6])](=[Sv2X1])[NX3])]" +111,153,Heterocyclic polycyclic aromatic hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]" +112,155,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1] +113,156,Azide and triazene groups,"[$([NX2!R]=[NX2!R][NX3!R]),$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]" +114,157,Aliphatic N-nitro group,"[NX3]([#1,C])([#1,C])[$([NX3+](=[OX1])[O-]),$([NX3](=O)=O)]" +115,158,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6] +116,159,Aromatic nitroso group,[a!r0][NX2]=[OX1] +117,160,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1 +118,166,Coumarins and furocoumarins,"[$(c1cccc2c1oc(=O)cc2),$(C1=CC(=O)OC2=CC=CC=C12),$(C1=CC(=O)Oc2ccccc12)]" +119,167,Halogenated benzene,"c1ccccc1[$([Br,Cl,F,I]);!$([Br,Cl,F,I]aa[Br,Cl,F,I]);!$([Br,Cl,F,I]aaa[Br,Cl,F,I]);!$([Br,Cl,F,I]aa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aaa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aa([OH])a([OH])aa[OH])]" +120,168,Halogenated PAH,"[Br,Cl,F,I][$([cR1]1[cR1][cR1][cR1][cR1][cR1]1-[cR1]2[cR1][cR1][cR1][cR1][cR1]2),$([cR1]1[cR1][cR1][cR1][cR2]2[cR2]1[cR1][cR1][cR1][cR1]2)]" +121,169,Halogenated dibenzodioxins,"[OR1]1[CR2]2=[CR1][CR1]=[CR1][CR1]=[CR2]2[OR1][CR2]3=[CR1][CR1]([F,Cl,Br,I])=[CR1][CR1]=[CR2]13" +122,170,Primary and secondary aromatic amines,"[$([a!r0][NX3;H2]),$([a!r0][NX3;H1][CH3]),$([a!r0][NX3;H1][CH2][CH3])]" +123,171,Tertiary aromatic amines,"a[NX3]([$([CH3]),$([CH2][CH3])])[$([CH3]),$([CH2][CH3])]" +124,172,Secondary aromatic acetamides and formamides,"[$([a!r0][NX3;H1][CX3;H1](=[OX1])),$([a!r0][NX3;H1][CX3](=[OX1])[CH3])]" +125,173,Nitroarenes,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=O)(=O))]" +126,174,Nitrosoarenes,[a!r0][NX2]=[OX1] +127,175,Arylhydroxylamines,"[a!r0][NX3;H1][OX2][#1,#6]" +128,176,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1] +129,177,N-Nitroso-N-alkylamides,"[CX4,a!r0][CX3](=[OX1])[NX3]([CX4])[NX2]=[OX1]" +130,178,N-Nitroso-N-alkylureas,"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[NX3H1][CX4,a!r0]" +131,179,N-Nitroso-N-alkylcarbamates (aka urethanes),"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[OX2][CX4,a!r0]" +132,180,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1] +133,181,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6] +134,185,Benzylic halides,"[a!r0][CH2][Cl,Br,I]" +135,186,Oxiranes and aziridines,"[CX4]1[OX2,NX3][CX4]1" +136,187,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]) +137,188,Alkyl esters of sulfonic and sulphuric acids,"[$([CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,a!r0][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])])]" +138,189,Alkyl esters of phosphonic and phosphoric acids,"[$([CX4,a!r0][Pv5X4](=[OX1])([OX2][$([CH3]),$([CH2][CH3])])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,#1][OX2][Pv5X4](=[OX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])])]" +139,190,Mixed alkyl esters of thiophosphoric acid,"[CX4][OX2][Pv5X4](=[SX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])]" +140,191,Haloethylamines,"[NX3]([#1,#6])([#1,#6])[CH2][CH2][Cl,Br,I,F]" +141,192,Haloalkylethers,"[$([#6][OX2][CH2][CH2][Cl,Br,I]),$([#6][OX2][CH2][Cl,Br,I])]" +142,193,α-Halocarbonyl or a-halohydroxy,"[$([CX3](=[OX1])[CH2][Cl,Br,I]),$([CX4!H0]([OH1])[CH2][Cl,Br,I])]" +143,194,Haloamines,"[#6][NX3]([#6])[Cl,Br,I,F]" +144,196,Allylic halides and alkoxides,"[CX3]=[CX3][CH2][$([Cl,Br,I]),$([OX2])]" +145,197,Halogenated methanes,"[CX4]([H,F,Cl,Br,I])([H,F,Cl,Br,I])([H,F,Cl,Br,I])[F,Cl,Br,I]" +146,198,Vinyl halides,"[CX3]=[CX3H1][Cl,Br,I]" +147,200,Isocyanate,[NX2]=[CX2]=[OX1] +148,201,Isothiocyanate,[NX2]=[CX2]=[SX1] +149,203,Alkyl esters of phosphonic or sulphonic acids,"[$([CX4,a][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]),$([CX4,a][Pv5X4](=[OX1])([OX2][#1,CX4])[OX2][CX4])]" +150,204,Aromatic nitro groups,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=[OX1])=[OX1]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]" +151,206,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1 +152,207,Aromatic mono- and dialkylamino groups,"[a!r0][$([NX3H1][CH3]),$([NX3H1][CH2][CH3]),$([NX3]([CH3])[CH3]),$([NX3]([CH3])[CH2][CH3]),$([NX3]([CH2][CH3])[CH2][CH3]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]" +153,208,Alkyl hydrazines,"[NX3]([CX4])([#1,CX4])[NX3]([#1,CX4])[#1,CX4]" +154,209,Alkyl aldehydes,"[$([CX3]([H])(=[OX1])[#1,CX4])&!$([CX3]([H])(=[OX1])[CX3]=[CX3])]" +155,211,Monohaloalkenes,"[CX3]([CX4,#1])(Cl)=[CX3]([!F!Cl!Br!I])[CX4,#1]" +156,212,"β-Haloethyl N, S - mustards","[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]" +157,213,N-Chloroamines,[#6][NX3]([#6])Cl +158,214,Propiolactones and propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]" +159,215,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1 +160,216,Aromatic and aliphatic substituted primary alkyl halides,"[F,Cl,Br,I][CH2][CX4,a]" +161,217,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2] +162,219,Aliphatic and aromatic epoxides,"[$([CX4]1[OX2][CX4]1),$([#6]1=[#6][#8]1)]" +163,221,Activated halo- or nitropyridines,"[$(c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])cc1),$(c1([F,Cl,Br,I,$(N(=O)=O)])ncccc1([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)]))]" +164,222,2-Halo- or 2-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncccn1" +165,223,4-Halo- or 4-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncncc1" +166,224,Activated 2-halo- or 2-nitropyrazines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])nc1" +167,225,Halo- or nitro s-triazines,"c1nc([F,Cl,Br,I,$(N(=O)=O)])ncn1" +168,226,Formaldehyde and thioformaldehyde,"[CH2]=[OX1,SX1]" +169,227,Aliphatic aldehydes and thioaldehydes,"[CX4][CX3H1]=[OX1,SX1]" +170,228,Aromatic aldehydes,[a][CX3H1]=[OX1] +171,229,"α, β-Unsaturated carbonyl and thiocarbonyl compounds","C(C)(C)=CC=[OX1,SX1]" +172,230,"α, β-Unsaturated ketones and thioketones","[C;!r5]([C;!r5])=[C;!r5][C;!r5](C)=[OX1,SX1;!r5]" +173,231,α-Diketones and α-dithiones,"[#6]C(=[OX1,SX1])C(=[OX1,SX1])[#6]" +174,232,β-Diketones and β-dithiones,"[#6]C(=[OX1,SX1])[CX4]C(=[OX1,SX1])[#6]" +175,233,"C-Nitroso compounds, iso(thio)cyanates, (thio)cyanate esters","[#6][$([NX2]=O),$(N=C=O),$(OC#N),$(SC#N),$(N=C=S)]" +176,234,Primary alkyl amines,[CH2][NH2] +177,235,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3] +178,236,"α, β-Unsaturated alkoxy","[$(CC(C)=[CH][CH2][OH]),$(CC=C(C)[CH2][OH])]" +179,237,Three-membered heterocycles derivatives,"[CH,CH2,CH3;!$([CH2]CC=[O,S])]([F,Cl,Br,I,$(OS(=O)(=O)[#6,#1]),$(OS(=O)(=O)O[#6,#1])])[#6]1[O,N,SX2][#6]1" +180,238,Lactones and their thio analogues,"C1C(=[O,S])[O,S][CH2,CH]1" +181,239,Esters of aromatic and unsaturated alcohols and their thio analogues,"[$(C=C),$(C#C),a][CH2,CH][O,S][$([CH]=O),$([CH]=S),$(C(C)=O),$(C(C)=S)]" +182,240,Aryloxy (arylthio) containing unsaturated compounds,"[$(C=C),$(C#C),a][CH2,CH][O,S][a]" +183,241,Aliphatic N-(thio)nitroso compounds,"[CH2,CH3][NX3][NX2]=[O,S]" +184,242,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1 +185,243,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23 +186,244,Activated alkene (Michael acceptor) (1),"[CH2,CH]=[CH][$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +187,245,Activated alkene (Michael acceptor) (2),"[CH2]=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +188,246,Activated alkene (Michael acceptor),"aC=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +189,247,Activated alkine,"C#C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +190,248,Activated conjugated dienes,"[CH2,CH]=[CH]C=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +191,249,Alkenes containing a gem-dihalo-substituted terminal double bond,"C=C([F,Cl,Br,I])[F,Cl,Br,I]" +192,250,Ortho-disubstituted benzenes,"c1c([O,NH2,NH])c([O,NH2,NH])ccc1" +193,251,Para-disubstituted benzenes,"c1c(=[O,NH2,NH])ccc(=[O,NH2,NH])c1" +194,252,Haloanhydrides,"[F,Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]" +195,253,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1 +196,254,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12 +197,255,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]) +198,256,Phosphorus halogen derivatives (1),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#6])[#6]" +199,257,Phosphorus halogen derivatives (2),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#6]" +200,258,Phosphorus halogen derivatives (3),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#8]" +201,259,Phosphorus halogen derivatives (4),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#7])[#6]" +202,260,Phosphorus halogen derivatives (5),"[Pv5X4]([F,Cl,Br,I])([#6])([#6])=[SX1]" +203,261,Phosphorus halogen derivatives (6),"[Pv5X4]([#8])([#6])([F,Cl,Br,I])(=[SX1])" +204,262,Phosphorus halogen derivatives (7),"[Pv5X4](=[SX1])([F,Cl,Br,I])([#16])[#6]" +205,263,Phosphorus V derivatives,[Pv5X4]([!#1])([!#1])([!#1])=[NX2] +206,266,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6] +207,267,Thiocyanates,[SX2][CX2]#[NX1] +208,268,Sulfonylhalides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]" +209,269,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6] +210,270,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4] +211,271,Alkylsulfates,"[#6,#1][OX2,OH1][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]" +212,272,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8] +213,273,All types of 3-valent phosphorus and similar (2),"[Pv3X3]([#8])([#8])[F,Cl,Br,I]" +214,274,All types of 3-valent phosphorus and similar (3),"[Pv3X3]([#8])([#6])[F,Cl,Br,I]" +215,275,All types of 3-valent phosphorus and similar (4),"[Pv3X3]([#6])([#6])[F,Cl,Br,I]" +216,276,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]) +217,277,All types of 3-valent phosphorus and similar (6),"[Pv3X3]([#8])([#7])[F,Cl,Br,I]" +218,278,All types of 3-valent phosphorus and similar (7),"[Pv3X3]([#7])([#7])[F,Cl,Br,I]" +219,279,All types of 3-valent phosphorus and similar (8),"[#16][Pv3X3]([#6])[F,Cl,Br,I]" +220,280,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7] +221,281,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]) +222,282,Hydroxamic acid haloanhydrides,"[CX3]([#6])([F,Cl,Br])=[NX2][#8]" +223,283,Halothioanhydrides,"[#6][CX3](=[SX1])[F,Cl,Br,I]" +224,284,Halocarbonates,"[#8][CX3](=[OX1])[F,Cl,Br,I]" +225,285,Halocarbamates,"[#7][CX3](=[OX1])[F,Cl,Br,I]" +226,286,Isocyanides,"[#6][$([NX2+]#[CX1-]),$([NX2]#[CX1])]" +227,287,Azides,"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]" +228,288,Thione esters,"[#6,#1][CX3](=[SX1])[OX2][#6]" +229,289,Acylsulfides,"[#6,#1][CX3](=[OX1])[SX2][#6]" +230,290,Thiones,[#6][CX3](=[SX1])[#6] +231,291,Thioamides,[#6][CX3](=[SX1])[#7] +232,292,Peroxides,[OX2][OX2] +233,293,Acyclic disulfides and polysulfides,[SX2!R][SX2!R] +234,294,Nitroso,[#6][NX2]=[OX1] +235,295,Nitrates,"[#6][OX2][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]" +236,296,N-Nitro,"[#7][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]" +237,297,N-Nitroso,[#7][NX2]=[OX1] +238,298,Azo,[#6][NX2]=[NX2][#6] +239,299,Azoxy,"[#6][$([NX2]=[NX3+]([O-])[#6]),$([NX2]=[NX3](=[OX1])[#6])]" +240,300,Nitroso dimers,"[$([#6][NX3+]([OX1-])=[NX3+]([OX1-])[#6]),$([#6][NX3](=[OX1])=[NX3](=[OX1])[#6])]" +241,302,Sulfenyl halides,"[#6][Sv2X2][F,Cl,Br,I]" +242,303,Sulfinyl halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]" +243,304,Diazonium salts,"[$([NX2+]#[NX1]),$([NX2]#N)]" +244,305,Cyclic and linear haloamidines,"[CX3](=[#7])([#7])[Cl,Br,I]" +245,307,Aldimines and ketimines,[#6][CX3]=[NX2][#6] +246,309,Hydrazones and similar,[CX3]=[NX2][NX3][#6] +247,310,Hydroxylamines,[OH1][NX3][#6] +248,311,N-Oxides,"[$([OX1-,OH1][#7X4+]([*])([*])([*])),$([OX1]=[#7X4v5]([*])([*])([*])),$([OX1]=[Nv5X3&!$([Nv5X3](=[OX1])=[OX1])](=[*])([*])),$([OX1-,OH1][#7X3+R](~[R])(~[R])),$([OX1]=[#7v5X3R](~[R])(~[R]))]" +249,312,Aminals,N[CX4]N +250,313,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]) +251,314,Sulfonium salts,[SX3+]([#6])([#6])([#6]) +252,315,α-Haloketones and similar,"[#6][CX3](=[OX1])[CX4][Cl,Br,I]" +253,316,β-Haloamines,"[NX3][CX4][CX4][Cl,Br,I]" +254,317,β-Halosulfides,"[Sv2X2][CX4][CX4][Cl,Br,I]" +255,318,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3] +256,319,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3] +257,320,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3] +258,321,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3] +259,322,Nitrovinyl,"[CX3]=[CX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]" +260,323,Acrylonitriles,[NX1]#CC=C +261,324,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3] +262,325,Vinylpyridines and similar,"[$(n1c([CX3]=[CX3])cccc1),$(n1cc([CX3]=[CX3])ccc1),$(n1ccc([CX3]=[CX3])cc1)]" +263,326,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1 +264,327,Ketenes,[CX3]=[CX2]=[OX1] +265,328,Allenes,C=C=C +266,329,Oxiranes,[CX4]1[OX2][CX4]1 +267,330,Thiiranes,[CX4]1[SX2][CX4]1 +268,331,Aziridines,[CX4]1[NX3][CX4]1 +269,332,Oxetanes,[CX4]1[OX2][CX4][CX4]1 +270,333,Thietanes,[CX4]1[SX2][CX4][CX4]1 +271,334,Selen in chain,[Sev2X2] +272,335,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]) +273,336,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]) +274,339,Benzylhalogenides and similar,"c1ccccc1([CX4][Cl,Br,I])" +275,340,Halomethyl ethers,"[F,Cl,Br,I][CX4][#8]" +276,341,Halomethyl thioethers,"[F,Cl,Br,I][CX4][#16]" +277,342,Halomethyl amines,"[F,Cl,Br,I][CX4][#7]" +278,343,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6] +279,344,Linear thioureas,N[CX3](=[SX1])N +280,345,Linear dithiocarbamates,N[CX3](=[SX1])S +281,346,Trithiocarbonates,[CX3](=[SX1])(S)S +282,347,Thioester,[CX3](=[SX1])([#6])S +283,348,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6] +284,349,Positively charged N-heterocycles,[#7v4X3R] +285,351,Organometallic compounds,"[$([Te]~[#6]),$([As]~[#6]),$([Ge]~[#6]),$([Hg]~[#6]),$([Co]~[#6]),$([Fe]~[#6]),$([Mn]~[#6]),$([Cr]~[#6]),$([Ti]~[#6]),$([Sn]~[#6])]" +286,352,"Isothiazolinone, isothiazolinthione and their derivatives","[#6]1=,:[#6]C(=[OX1,SX1])N[SX2]1" +287,354,Acyl and thioacyl halides,"[!$(C=C);!$(C#C)]C(=[O,SX1])[F,Cl,Br,I]" +288,355,Imidoyl halides,"[!$(C=C);!$(C#C)]C(=N)[F,Cl,Br,I]" +289,356,Esters of aromatic alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][a]" +290,357,Acid anhydrides and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N]C(=[O,SX1,N])" +291,358,Esters of unsaturated alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,S,N])[O,S][$(C=C),$(C=N),$(C#C),$(C#N)]" +292,359,"β-Lactones, β-lactams and their thio analogues","[#6]1C(=[O,S])[O,N,S][#6]1" +293,360,Benzo-fused five-membered heterocycles,"[C,N,O,S,a]c1[n,o,s]c2ccccc2[n,o,s]1" +294,361,(Thio)carbonyl and imine derivatives of five-membered heterocycles,"[#6]1[#6](=[N,O,S])[#7,#8,#16][#6][#7,#8,#16]1" +295,362,Phthalic anhydrides and their thio and aza analogues,"[C,O]=[#6]1[#7,#8,#16][#6](=[O,N,SX1])c2ccccc12" +296,363,Acylating agents,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][CX4,O,S][$(C=O),a,$(C=C),$(C#C),$(C=N),$(C#N)]" +297,364,Heteryl-substituted benzenes,"C1=[C,N][$(S(=O)(=O)),$(C=[N,O]),$(S=O)][C,N]=C1c2ccccc2" +298,365,Cyclopentanone and cyclopentathione derivatives,"[CH2,CH]=C1C(=[OX1,SX1])**C1" +299,366,"Ortho-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])c([OH,NH2,NH,$(N=N),$(N(C)C)])ccc1" +300,367,"Para-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])ccc([OH,NH2,NH,$(N=N),$(N(C)C)])c1" +301,368,"Meta-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])cc([OH,NH2,NH,$(N(C)C)])cc1" +302,369,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1 +303,370,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1 +304,371,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1 +305,373,Haloethyl-substituted aromatic compounds,"C([F,Cl,Br,I])[CH2,CH][a]" +306,375,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1 +307,376,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1 +308,377,α-Naphthols,[OH]c1cccc2ccccc12 +309,378,vic-Difluoroalkyl group,"F[CH2,CH]C(F)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +310,379,vic-Dichloroalkyl group,"Cl[CH2,CH]C(Cl)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +311,380,vic-Dibromoalkyl group,"Br[CH2,CH]C(Br)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +312,381,vic-Diiodoalkyl group,"I[CH2,CH]C(I)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]" +313,384,Carboxylic acid anhydrides,"[$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6]1),$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6][#6]1)]" +314,385,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl +315,389,Lactones,"[$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6]1),$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6][#6]1)]" +316,392,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6] +317,393,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6] +318,394,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]) +319,395,Cyclic sulfonic acid esters,"[$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]" +320,396,Cyclic sulfuric acid esters,"[$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]" +321,397,Halo acetates,"[F,Cl,Br,I][#6][CX3](=[OX1])[OX2H1]" +322,398,Halo acetamides,"[F,Cl,Br,I][#6][CX3](=[OX1])[NX3]" +323,399,Halo ethers,"[$([F,Cl,Br,I]C[OX2]C),$([F,Cl,Br,I]CC[OX2]C)]" +324,400,Haloethyl sulfides (S-mustard),"[F,Cl,Br,I][CX4][CX4][SX2]" +325,401,Haloethyl amines (N-mustard),"[F,Cl,Br,I][CH2][CH2][NX3]" +326,402,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3] +327,403,"α, β-Unsaturated nitriles",C=CC#[NX1] +328,404,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1] +329,405,"α, β-Unsaturated nitro compounds","[#6]=[#6][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]" +330,406,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]) +331,407,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6] +332,408,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1] +333,409,"α, β-Unsaturated carbonyl compounds",[#6]=[#6][CX3](=[OX1])([!#1!$([OH1])]) +334,411,Alkyl halide,"[*!$([a])&!$(C=C)&!$(C#C)][CX4][F,Cl,Br,I]" +335,413,Aryl halide,"[a!r0][F,Cl,Br,I]" +336,414,Halogenated allylic group,"[F,Cl,Br,I][CX4][CX3]=[CX3]" +337,415,Halogenated benzylic group,"c[CX4][F,Cl,Br,I]" +338,417,Diazo compounds,"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]" +339,418,Organo metallic compounds,"[$([Cu][#6]),$([Ag][#6]),$([Au][#6]),$([Zn][#6]),$([Cd][#6]),$([Hg][#6]),$([Sn][#6]),$([Pb][#6]),$([As][#6]),$([Sb][#6])]" +340,419,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]) +341,420,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]) +342,421,Iodine,II +343,422,Hydrogen peroxide,[#1][OX2][OX2][#1] +344,423,Sulfoxides,[Sv4X3](=[OX1]) +345,424,Sulfenyl iodides,[SX2][IX1] +346,426,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]) +347,427,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]) +348,428,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2] +349,429,Arsenic (III) compounds,[OX1]=[AsX2] +350,466,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl +351,467,(Dithio) carbamates,"[OX2,SX2][CX3](=[OX1,SX1])[NX3]" +352,478,Organotin compounds,[Sn][#6] +353,479,Pyrethroids,"[$(CC(=C[CH]1C([CH]1C(=O)OC1C(=C(C(=O)C1)CC=CC=C)C)(C)C)C),$(C(=C[CH]1C([CH]1C(=O)O[CH]1C(=C(C(=O)C1)CC=CC=C)C)(C)C)(C)C(=O)OC)]" +354,480,Organophosphorothionate esters,"[Pv5X4](=[SX1])([OX2][#6])([OX2,SX2][#6])([OX2,SX2][#6])" +355,482,Acetates,"[CH,$([C!R](=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R,NX3!R][$([a;r6]),$([a;r5]),$(C=C),$(C#C)]" +356,483,Acyclic anhydrides,"[CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R][CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])]=[O,SX1]" +357,484,Dialkyl carbamoylhalides,"[NH2!R,$([NH!R](C=O)[#6!R]),$(N(C=O)([#6!R])[#6!R])]C(=O)[F,Cl,Br,I]" +358,486,Phosphonic acid halides,"[#6]O[P!R](=O)(O[#6])[F,Cl,Br,I,$(C#N)]" +359,487,Cyclopropenones,"[#6]1([#1,#6])=,:[#6]([#1,#6])-,:[#6]1=O" +360,488,β-Lactones,C1C(=O)OC1 +361,489,Thio-lactones,C1C(=O)SC1 +362,491,Azlactones,"C1=[O,SX2,NX2,CX3]CC(=[O,SX2])[O,SX2,NX3]1" +363,492,Cyclic anhydrides,"[#6R,#8R,#16X2R][#6R](=[O,SX1])[#8R,#16X2R][#6R]([#6,#8R,#16X2])=[#8,#16X1]" +364,496,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6] +365,498,Polarised alkene-aldehydes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][CH]=O" +366,499,Polarised alkene-ketones,"[$([$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[#6]);!$([#6X3]1=,:[#6X3H][CX3](=[OX1])[#6X3]=,:[#6X3][#6X3]1(=[OX1]));!$([CX3]1(=[OX1])[CX3](=[OX1])[#6X3]=,:[#6X3H][#6X3]=,:[#6X3]1)]" +367,500,Polarised alkene-esters,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)O[#6]" +368,501,Polarised alkene-amides,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]" +369,502,Polarised alkene-nitros,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]" +370,503,Polarised alkene-cyanos,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C#N" +371,504,Polarised alkene-alkyl sulphonates,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)O[#6]" +372,505,Polarised alkene-alkyl sulfones,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)[#6]" +373,506,Polarised alkene-alkyl sulfinyls,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][SX3](=O)[#6]" +374,507,Polarised alkene-oximes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C=[NX2][OH]" +375,508,Polarised alkene-pyridines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncccc1),$(c1ccncc1)]" +376,509,Polarised alkene-pyrazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]c1nccnc1" +377,510,Polarised alkene-pyrimidines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncc1),$(c1ncccn1),$(c1cncnc1)]" +378,511,Polarised akene-triazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1),$(c1nnncc1),$(c1cnnnc1)]" +379,512,Azocarbonamides,"[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]C(=O)N=NC(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]" +380,513,Allyl alcohols,"[CH2,$([CH](=C)[#6])]=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]" +381,514,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1] +382,515,Polarised alkyne-aldehydes,"[CH,$(C(#C)[#6])]#C[CH]=O" +383,516,Polarise alkyne-ketones,"[CH,$(C(#C)[#6])]#CC(=O)[#6]" +384,517,Polarised alkyne-esters,"[CH,$(C(#C)[#6])]#CC(=O)O[#6]" +385,518,Polarised alkyne-amides,"[CH,$(C(#C)[#6])]#CC(=O)[$([NH2]),$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]" +386,519,Polarised alkyne-nitros,"[CH,$(C(#C)[#6])]#C[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]" +387,520,Polarised alkyne-cyano,"[CH,$(C(#C)[#6])]#CC#N" +388,521,Polarised alkyne-alkyl sulphonates,"[CH,$(C(#C)[#6])]#CS(=O)(=O)O[#6]" +389,522,Polarised alkyne-alkyl sulfones,"[CH,$(C(#C)[#6])]#CS(=O)(=O)[#6]" +390,523,Polarised alkyne-alkyl sulfinyls,"[CH,$(C(#C)[#6])]#C[SX3](=O)[#6]" +391,524,Polarised alkyne-pyridines,"[CH,$(C(#C)[#6])]#C[$(c1ncccc1),$(c1ccncc1)]" +392,525,Polarised alkyne-pyrazines,"[CH,$(C(#C)[#6])]#Cc1nccnc1" +393,526,Polarised alkyne-pyrimidines,"[CH,$(C(#C)[#6])]#C[$(c1ncccn1),$(c1cncnc1),$(c1ncncc1)]" +394,527,Polarised alkyne-triazines,"[CH,$(C(#C)[#6])]#C[$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1)]" +395,528,Propargyl alcohols,"[CH,$(C(#C)[#6])]#C[CH2][OH]" +396,529,Benzoquinones,"[$(C1(=O)[#6]=,:[#6]C(=O)[CH]=C1),$(C1(=O)C(=O)[#6]=,:[#6][CH]=C1)]" +397,530,Quinone-imines,"[$(C1(=O)[#6]=,:[#6][$(C=[NH]),$(C=N[CX4])][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])]C=[CH][#6]=,:[#6]1)]" +398,531,Quinone-diimines,"[$([CH]1=C[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][$(C=[NH]),$(C=N[CX4])]1),$([CH]1=C[$(C=[NH]),$(C=N[CX4])][$(C=[NH]),$(C=N[CX4])][#6]=,:[#6]1)]" +399,533,Aminophenols,"[$(c1([OH])c[cH]c([NH2])cc1),$(c1([OH])c([NH2])cc[cH]c1)]" +400,534,Benzenediamines,"[$(c1([NH2])c[cH]c([NH2])cc1),$(c1([NH2])c([NH2])cc[cH]c1)]" +401,535,Quinone-methides,"[$(C1=CC(=O)[#6]=,:[#6]C1(=[CH][CX4])),$(C1(=[CH][CX4])C(=O)[#6]=,:[#6]C=C1)]" +402,536,Pyranones,"[$([cH]1cc(=[O,NH])cc[o,n]1),$([cH]1cc(=[O,NH])[o,n]cc1),$(c1cc(=[O,NH])[o,n][cH]c1)]" +403,537,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2" +404,539,Mono-aldehydes,"[CH2,$([CH](=O)[CX4]),$([CH](=O)c1a(*)caaa1),$([CH](=O)c1a(*)aaa1)]=O" +405,540,Aliphatic amines,[#6][CH2][NX3H2] +406,541,"Di-substituted α,β-unsaturated alkenes (polarized by an aldehyde moiety)","[$(C(=C)([#6])[#6]);!$(C(=C)([#6])C=[CH2,CH])]=C[CH]=O" +407,542,Di-substituted allyl alcohols,"C([#6])([#6])=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]" +408,543,"1,2-Dicarbonyls","[CH,$(C(=O)(C=O)[CX4]),$(C(=O)(C=O)c1a(*)aaaa1),$(C(=O)(C=O)c1a(*)aaa1)](=O)[CH,$(C(=O)(C=O)[#6]);!$(C(=O)(C=O)C=[CH2,CH]);!$(C(=O)(C=O)C#C)]=O" +409,544,"1,3-Dicarbonyls","[CH,$(C(=O)([CX4]C=O)[CX4]),$(C(=O)([CX4]C=O)c1a(*)aaaa1),$(C(=O)([CX4]C=O)c1a(*)aaa1)](=O)[CX4][CH,$(C(=O)([CX4]C=O)[#6]);!$(C(=O)([CX4]C=O)C=[CH2,CH]);!$(C(=O)([CX4]C=O)C#C)]=O" +410,545,Ethylenediamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][NH2]),$([NH]1[CH2][CH2][NH][CH2][CH2]1)]" +411,546,Ethanolamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][OH]),$([NH]1[CH2][CH2]O[CH2][CH2]1)]" +412,547,Piperizines,[NH]1CC[NH1]CC1 +413,548,Morpholines,O1CC[NH1]CC1 +414,549,Alkyl halides,"[CH3,$([CH2]([F,Cl,Br,I])[#6]),$([CH]([F,Br,Cl,I])([#6])[#6]);!$([CH2,CH]C=O);!$([CH2,CH][CX4][NX3,SX2]);!$([CH2,CH][CX4][F,Cl,Br,I])][F,Cl,Br,I]" +415,550,Alkyl diazos,"[CH3,$([CH2](N=N)[#6]),$([CH](N=N)([#6])[#6])][NX2]=[NH,$(N(=N)[#6])]" +416,551,Alkyl sulfates,"[#6]OS(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]" +417,552,Alkyl sulphonates,"[#6]S(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]" +418,553,Alkyl (thio)phosphates,"[#6][O,SX2]P(=[O,SX1])([O,SX2][#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]" +419,554,Alkyl (thio)phosphonates,"[#6][O,SX2]P(=[O,SX1])([#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]" +420,555,Allyl acetates,"[#6]C(=[O,SX1])[O,SX2][CH2,$([CH]([O,SX2])[#6])][c,CX3,CX2]" +421,556,α-Halocarbonyls,"[$([CH]=[O,SX1]),$(C([#6])=[O,SX1])][CH2,$([CH](C=[O,SX1])[#6])][F,Cl,Br,I]" +422,559,α-Haloalkynes,"[CH,$(C(#C)[#6])]#C[$([CH2](C#C)[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH](C#C)([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]" +423,560,α-Halobenzyls,"[c][$([CH2]([c])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH]([a])([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]" +424,564,Sulfuranes,C1[SX2]C1 +425,566,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1 +426,567,Nitrosoureas,"[NX3]C(=O)[$([NH](C=O)[NX2]=O),$(N(C=O)([#6])[NX2]=O)]" +427,568,Nitrosoguanidines,"[NX3]C(=[NH])[$([NH](C=[NH])[NX2]=O),$(N(C=[NH])([#6])[NX2]=O)]" +428,569,N-Acytoxy-N-acetylphenyls,"[a][NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]" +429,570,N-Acytoxy-N-alkoxyamides,"[#6]O[NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]" +430,573,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6] +431,574,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6] +432,577,Aromatic sulphonic acids,[a][SX4](=O)(=O)[OH] +433,578,Isothiazol-3-ones,"[cH,$(c(c)([sX2])[#6])]1[cH,$(c(c)(c=O)[#6])]c(=O)[nH,$(n(c=O)([sX2])[#6])][sX2]1" +434,579,Isothiazolin-3-ones,"[CH2,$([CH](C)([SX2])[#6])]1[CH2,$([CH](C)(C=O)[#6])]C(=O)[NH,$(N(C=O)([SX2])[#6])][SX2]1" +435,580,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl +436,582,Polarized alkenes with a halogen leaving group,"C=[CH][F,Cl,Br,I]" +437,583,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6] +438,584,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6] +439,585,Polarized alkenes with an alkyl (thio)phosphonate leaving group,"C=[CH]OP(=[O,SX])(O[#6])[#6]" +440,586,Polarized alkenes with an alkyl (thio)phosphate leaving group,"C=[CH]OP(=[O,SX])(O[#6])O[#6]" +441,587,Mustards,"[NX3,SX2][CH2,$([CH]([NX3,SX2])([CX4])[CX4])][CH2,$([CH]([CX4])([Cl,Br,I])[CX4])][Cl,Br,I]" +442,588,"1,2-Dihaloalkanes","[Cl,Br,I][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][Cl,Br,I]" +443,594,Activated pentafluorobenzenes,"c1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-]),$([CH]=O),$(C#N),$(C(=O)[CH3])])c(F)c(F)c(F)c(F)c1(F)" +444,596,Formaldehyde releasers (1),"[$(O1COCC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C1),$([OX2H1]CC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C[OX2H1])]" +445,597,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]) +446,598,Formaldehyde releasers (3),"C1(=[OX1])[NX3H1]C(=[OX1])[NX3H1][CX4]1(C[OH1])[NX3H1][CX3](=[OX1])[NX3!H0][#1,#6]" +447,599,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1] +448,600,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1] +449,602,"Hydrazine, hydrazides","[#6,#1][NX3H1][NX3H1][#6,#1]" +450,603,Nitrobenzenes,"a[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]" +451,604,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3 +452,605,Benzylamines,"[#1,CX4!R][NX3]([#1,CX4!R])[CH2]c1ccccc1" +453,606,Propargyl amines,"[#1,CX4,$(c1ccccc1)][CX2]#[CX2][NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]" +454,607,Cyclopropyl amines,"[CX4]1[CX4][CX4]1[NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]" +455,608,"N-Substituted-4-aryl-1,2,3,6-tetrahydropyridines","[NX3]1([CX4!R])[CX4][CX3]=[CX3](c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1" +456,609,N-Substituted-4-arylpiperidin-4-ol,"[NX3]1([CX4!R])[CX4][CX4][CX4]([OH1])(c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1" +457,610,Formamides,[CX3H1](=[OX1])[NX3H1][#6] +458,611,Hydantoins (glycolylurea),"[NX3H1]1[CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NX3H1][CX3]1(=[OX1])" +459,613,Thioureas,"[#1,#6][NX3]([#1,#6])[CX3](=[SX1])[#7]" +460,614,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6] +461,617,Ortho- or parahydroquinones,"[$(c1([OH1])c([OH1])cccc1),$(c1([OH1])ccc([OH1])cc1)]" +462,618,Ortho- or paraquinones,"[$([#6]1(=[OX1])-,:[#6]=,:[#6]-,:[#6](=[OX1])-,:[#6]=,:[#6]1),$([#6]1(=[OX1])-,:[#6](=[OX1])-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)]" +463,619,Ortho- or paraalkylphenols,"[$(c1([OH1])c([CX4]([#1,#6])[#1,#6])cccc1),$(c1([OH1])ccc([CX4]([#1,#6])[#1,#6])cc1)]" +464,620,Quinone methide,"[$([OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]-,:[#6X3]1=[CX3]([#1,#6])[#1,#6]),$([OX1]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[CX3]([#1,#6])[#1,#6])-,:[#6]=,:[#6]1)]" +465,621,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1 +466,622,3-Methylene indoles,"c1ccc([nX3]2([#1,#6]))c(c([CH2][#1,#6])c2)c1" +467,623,Furans,c1ccc[oX2]1 +468,624,Thiophenes,c1ccc[sX2]1 +469,625,Thiazoles and 2-amino derivatives,"[$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([#1,CX4!R])[sX2]1),$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([NX3]([#1,CX4!R])[#1,CX4!R])[sX2]1)]" +470,626,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6] +471,629,2- or 4-Halopyridines,"[$(n1c([Cl,Br,I,F])cccc1),$(n1cccc([Cl,Br,I,F])cc1)]" +472,631,Alkynes,"[#6][CX2]#[CX2][#1,#6]" +473,633,Alkylhalides,"[$([CX4]([F,Cl,Br,I])([H,!F!Cl!Br!I])([H,!F!Cl!Br!I])[H,!F!Cl!Br!I]),$([CX4]([#6])([F,Cl,Br,I])([F,Cl,Br,I])[H,!F!Cl!Br!I])]" +474,634,Carboxylic acids,[#6][CX3](=[OX1])[OH1] +475,635,Fluoroethyl ethers and amines,"[$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][OX2][#1,#6]),$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][NX3][#6])]" +476,636,Three-membered heterocycles,"[#6]1~[#6][#7,#8,#16]1" +477,637,Thioles,[Sv2X2H1] +478,641,Chlor(brom)anhydrides,"[CX3](=[OX1])[Cl,Br]" +479,642,Sulphonic acids/esters,S(=O)(=O)O +480,643,Trihalogensubstituted ketones,"[CX3](=[OX1])[CX4]([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]" +481,644,Monohalogen substituted ketones,"[CX3](=[OX1])C[Cl,Br,I]" +482,646,Sulphonhalogenanhydrides,"S(=[OX1])(=[OX1])[F,Cl,Br,I]" +483,647,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1] +484,648,Phosphorus,P +485,650,Selen,[Se] +486,651,Bor,B +487,652,Silicium,[Si] +488,653,"Isocyanates, isothiocyanates","[NX2]=[CX2]=[OX1,SX1]" +489,654,Thione,[CX3]=[SX1!R] +490,655,β-halogen substituted carbonyls,"[CX3](=[OX1])CC[F,Cl,Br,I]" +491,656,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1] +492,657,gem-Dihalo propane and cyclopropane,"CC([Cl,Br,I])([Cl,Br,I])C" +493,658,Activated halides (o-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cc[F,Cl,Br]" +494,659,Activated halides (p-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cccc[F,Cl,Br]" +495,660,Activated halides (α-halogen substituted N-heterocycles),"nc[F,Cl,Br]" +496,661,Activated halides (γ-halogen substituted N-heterocycles),"nccc[F,Cl,Br]" +497,662,Thiourea,[#7][CX3](=[SX1])[#7] +498,663,Barbiturates,"N1C(=[OX1,SX1])NC(=[OX1,SX1])C(=C)C1(=[OX1,SX1])" +499,664,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2] +500,665,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C +501,666,Crown ethers,[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C +502,667,Coumarins (1),"c1cccc2c1oc(=O)c([$(C=[OX1]),$(C=[SX1]),$(S=[OX1]),$(C#[NX1]),F,Cl,Br,I,$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]));!$([CX3](=[OX1])[OH1])])[c!H0]2" +503,668,Coumarins (2),"[cH1]1[cH1]c2c3[cH1][cH1]c(cc3oc(=O)c2[cH1]c1[OX2][$([CH2]),$([CH3])])[OX2][C!H0]" +504,669,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2 +505,670,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2 +506,671,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2 +507,672,Coumarins (6),"c1([F,Cl,Br,I])cc([F,Cl,Br,I])cc2c1oc(=[NX2H1])c([CX3](=[OX1])[NH2])[c!H0]2" +508,673,Coumarins (7),c1cccc2c1oc(=[NX2])cc2 +509,674,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1 +510,675,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1] +511,676,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1] +512,677,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C +513,678,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1] +514,679,o-Quinones (3),"CC(=[OX1])C(=[OX1])[#6,#7]" +515,680,o-Quinones (5),CC(=[OX1])C(=S)C +516,681,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4" +517,682,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O" +518,683,Hydroquinone,c1c([OH1])c([OH1])ccc1 +519,684,N-N Single bound not in a ring,[N!R][N!R] +520,685,Ketal,CC([OX2]C)([OX2]C)C +521,686,Acetal,[CX4H1](C)([OX2]C)([OX2]) +522,687,Acyl and sulfinyl cyanide,"[$(C(=[OX1])[CX2]#[NX1]),$(S(=[OX1])[CX2]#[NX1])]" +523,688,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1" +524,689,Hydrazine and other nucleophilic NH2-groups,"[NX3H2][#7,#8]" +525,692,Activated halo- and sulfonyl-aromatics,"c1([F,Cl,Br,I,$(C(C)=NO),$([CX2]#[NX1]),$([CX3]=[OX1]),$([CX4](F)(F)F),$([SX4](=[OX1])=[OX1]);!$([CX3](=[OX1])[OH1])])na([F,Cl,Br,I,$([SX4](=[OX1])(=[OX1])C)])a([!#7])a([!#7])a1" +526,693,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1] +527,694,Acyclic gem-dihalosubstituted carbon atom,"[C!R]([Cl,Br,I])[Cl,Br,I]" +528,695,Imines,"[N!R]=[C,N]" +529,697,Michael acceptors (carbonyl containing acrylonitrile derivatives),C[CX3H1]=[CX3!R](C(=[OX1])[!#1]~[!#1])[CX2]#[NX1] +530,698,Over halogenated rings,"a1c([F,Cl,Br,I])c([F,Cl,Br,I])ac([F,Cl,Br,I])a1" +531,699,o-Quinones (1),"[CX3]1(=[!#1!#6])[CX3](=[!#1!#6])[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1" +532,700,o-Quinones (2),CC(=[!#1!#6;!R])C(=[!#1!#6;!R])C +533,701,o-Quinones (4),CC(=[!#1!#6;!R])S(=[OX1])(=[OX1]) +534,702,p-Quinones (1),"[#6X3]1=,:[#6X3][CX3](=[!#1!#6])[#6X3]=,:[#6X3][#6X3]1(=[!#1!#6])" +535,704,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9 +536,705,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8 +537,706,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2 +538,707,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2 +539,708,Acid anhydrides and analogues,[!#1](=O)O[!#1]=O +540,709,Acyl halides and analogues,"[C,S](=[O,S])[F,Br,Cl,I]" +541,711,Cyano carbonyl compounds ,N#CC(=O) +542,714,Methylendiamines (1),"[!$([C,S]=O)]N([!$([C,S]=O)])[CX4]N([!$([C,S]=O)])[!$([C,S]=O)]" +543,715,Methylendiamines (2),"[!$([C,S]=O)][NH][CX4]N([!$([C,S]=O)])[!$([C,S]=O)]" +544,716,Methylendiamines (3),"[!$([C,S]=O)][NH][CX4][NH][!$([C,S]=O)]" +545,717,N-Acetoxy amines and their thio analogues,"[#7][#8][C,S]=O" +546,718,α-Halogen substituted N-heterocycles,"[F,Br,Cl,I]-cn" +547,719,Activated haloaromatics,"[F,Cl,Br,I][$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]" +548,720,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2] +549,721,Benzyl ammoniums,cC[NX4+] +550,722,α-Carbonyl ammoniums,C(=O)[#6][NX4+] +551,723,Cations,"[#6+,#17+,#53+,#15+,#16+]" +552,725,Enamines,[#6][CX3](!@N)=[CX3][#6] +553,727,Halogen-bonded heteroatoms,"[!#1&!#6][F,Cl,Br,I]" +554,728,Cumulated double bonds,"[C,N]=C=[C,O,N,S]" +555,729,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn +556,730,Singel acyclic N-N bonds,[#7]!@-N +557,732,Activated double bonds (1),[C!H0]=C(C#N)C(=O) +558,733,Activated double bonds (2),[!c][C!H0]=CC=O +559,734,Activated double bonds (3),"[C!H0]=C[S,N]=O" +560,735,N-Acyl substituted azoheterocycles,nC(=O)[#6] +561,736,Singel acyclic N-S bonds,[NR0]-[SR0!v6] +562,737,Acetoxy group attached to the substituted aromatic ring,"C(=O)O[$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]" +563,738,"Oxetanes, thietanes","C1[O,S]CC1" +564,739,Trihalomethyl ketones,"CC(=O)C([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]" +565,741,Phosphonates,[#6]P(=O)O[#6] +566,742,Phosphorus containing compounds ,"NP(=[N,O,S])" +567,743,p-Quinones,O=C1C=CC(=O)C=C1 +568,744,o-Quinones,O=C1C(=O)C=CC=C1 +569,745,"C, N, O, P and S atoms in unusual valence states","[#6!v4+0,#7!v3+0,#8!v2+0,#15!v3!v5+0,#16!v2!v4!v6+0]" +570,747,Sulfurous acid esters,[!#1]OS(=O)O +571,749,Heteroatom-bonded thiocarbonyls,"C(=S)[O,S,N]" +572,750,Thiocarboxylic acids and their derivatives,[CR0](=O)S +573,752,Thiocarbonyls,C(=S)[!#1!H0] +574,753,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O +575,754,Trifluoromethyl sulfinyls,FC(F)(F)S(=O) +576,755,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O +577,756,Anthracenes,c12ccccc1cc3ccccc3c2 +578,757,Double acyclic N=N and N=S bonds,"[NR0,SR0]=[NR0]" +579,758,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1 +580,759,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6] +581,760,"Iodosos, chlorosos","[Cl,I]=O" +582,761,Acid grops,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]" +583,763,Phosphocyanates,PC#N +584,764,α-Hydroxy nitriles,N#CC[OH] +585,765,α-Diketones,[CX3R0](=O)[CX3R0](=O) +586,768,Singel acyclic N-O bonds,[NR0v3]-[OR0] +587,770,Activated double bonds (4),C=C(C#N)(C#N) +588,773,Nitrites,[!#1]ON=O +589,775,Nitroso compounds,[NX2]=O +590,776,"Any atoms except organogens, halogens, P, S, K, Na, Mg, Ca",[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53] +591,777,Double P=S and P=C bonds,"P=[S,#6]" +592,778,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F) +593,779,Phenanthrenes,c12ccccc1ccc3ccccc23 +594,780,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1 +595,781,Phosphorus derivatives,[P!v5] +596,782,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0] +597,783,Carboxylic acid esters,[CX4]C(=O)O[#6][!#1] +598,785,"N,N-Dialkyl aniline derivatives (1)","[CX4][NX3]([CX4])c1cc([$([CX4]),$(O[CX4][CX4])])c([#7])[cH]c1" +599,786,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1 +600,787,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1 +601,788,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1 +602,789,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1 +603,790,"N,N-Dialkyl aniline derivatives (4)","[CX4]N([CX4])c1ccc([CX4][$([OH]),$(C=[C!H0]),$(N[CX4])])cc1" +604,791,"N,N-Dialkyl aniline derivatives (5)","[CX4]N([C!H0])c1[cH][cH]c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1" +605,792,"N,N-Dialkyl aniline derivatives (6)","[CX4]N([C!H0])c1[cH]c([CX4])c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1" +606,793,Phosphoric anhydrides,P(=O)OP(=O) +607,795,Five-membered heterocycles (1),"C1(=C)C(=O)[#7,#8,#15,#16]N=C1" +608,796,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1 +609,797,Six-membered heterocycles,"[#7,#8,#15,#16]~C1~[#7,#8,#15,#16]~C[#7,#8,#15,#16][CX3](=[#7,#8,#15,#16])[CX3]1(=[C!H0])" +610,798,Glutarimides,C1CC(=O)NC(=O)C1 +611,799,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4] +612,800,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1 +613,801,p-Substituted phenols,[OH]c1ccc(C=NN)cc1 +614,802,"1,2-Diimines, 1,2-diketones and their thio- and phospho-analogues","[#6][#6](=[#7,#8,#15,#16])[#6](=[#7,#8,#15,#16])[#6,Sv6]" +615,803,Indolones,O=C1[#7]c2ccccc2C1=N[#7] +616,804,NH-Indoles,"[nH]1c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12" +617,805,N-Alkyl substituted indoles,"n1([CH2])c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12" +618,806,Macrocycles,"[*r10,*r11,*r12,*r13,*r14,*r15,*r16,*r17,*r18,*r19,*r20,*r21,*r22,*r23,*r24,*r25,*r26,*r27,*r28,*r29,*r30]" +619,807,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1 +620,808,N-Allophanoylamides and their thio analogues,"NC(=[O,S])NC(=[O,S])NC=[O,S]" +621,809,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1 +622,810,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12 +623,811,N-Phenylpyrrole derivatives,N1(c2[!#1]cccc2)C([CX4])=C[C!H0]=C1[CX4] +624,812,"Quinones, quinone-(di)imines and their thio- and phospho-analogues","[#7,#8,#15,#16]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[#7,#8,#15,#16])-,:[#6]=,:[#6]1" +625,813,Five-membered heterocycles (2),"[#7]=C1S[CH]=C([$([CH2]),$(c:c)])N1" +626,814,Five-membered heterocycles (3),"[#7]=C1SC([$([CH2]),$(C=O)])=C([$([CH2]),$(c:c)])N1" +627,815,Tert-butyl carbon atom,c[CX4](c)c +628,816,Acethylenes,"[CH2,CH3]C#C[CH2,CH3]" +629,819,α-Halonitriles,"[F,Cl,Br,I][CX4][CX2]#[NX1]" +630,822,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0] +631,823,Benzthiozolium like compounds,"[#7,#8,#16]1-,:[#6]=,:[#6]-,:[#7+]2=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6]21" +632,825,Cyanates,"[NX2]=[CX2]=[OX1,SX1]" +633,826,Di-carbonyls,"[#1,#6][CX3](=[OX1])[CX3](=[OX1])[#1,#6]" +634,828,Haloalkyl,"[C!H0]([#1,#6,#7,#8,#16])[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])[Cl,Br,I]" +635,829,"Haloalkyl group attached to S, N or O atoms","[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])([Cl,Br,I])[#7,#8,#16]" +636,830,Haloethylenes,"[CX3!H0]=[CX3]([#1,Cl,Br,I])[Cl,Br,I]" +637,831,Halopyridines,"c1([F,Cl,Br,I])n[c,n][c,n][c,n][c,n]1" +638,832,Heptanes,"[CH3][CH2][CH2][CH2][CH2][CH2][CH2,CH3]" +639,835,N-Oxides (six-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1)]" +640,836,N-Oxides (five-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1)]" +641,838,Phosphorus cations,[#15+] +642,841,Peroxide like compounds,"O[F,Cl,Br,I]" +643,842,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6] +644,843,Double P=O bonds,[#15]=O +645,844,Pyridinium like compounds,"[#6][#7+]1=,:[#6]-,:[#6,#7]=,:[#6]-,:[#6,#7]=,:[#6]1" +646,845,Quinolizinium like compounds,"[#6,#7]1=,:[#6,#7]-,:[#6,#7]=,:[#7+]2-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6]2=,:[#6,#7]1" +647,847,Sulfates,"[Sv6X4](=[OX1])(=[OX1])([#8])[#6,#8]" +648,848,Thio aldehydes,"[#6,#1][CX3]([H])=[SX1]" +649,849,Thio halogens,"[#16][F,Cl,Br,I]" +650,850,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]" +651,853,Thiozolium like compounds,"[#6][#7+]1=,:[#6]-,:[#7,#8,#16]-,:[#6]=,:[#6]1" +652,854,Acyl Halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]" +653,855,Sulphonyl Halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]" +654,856,Alkyl Halides,"[CX4][F,Cl,Br,I]" +655,859,Activated Halides,"[$(c([F,Cl,Br,I])c[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])aac[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])n),$(c([F,Cl,Br,I])aan)]" +656,860,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]) +657,861,Aldehydes (including aminoformyl moieties),"[$([#1,#6][CX3]([H])=[OX1]),$([#7]([#1,#6])([#1,#6])[CX3H1]=[OX1])]" +658,866,Nitrosos,[NX2]=[OX1] +659,870,Picrates,"c1([OH1,O-])c([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])" +660,871,Perchlorates (periodates),"[$([Clv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-]),$([Iv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-])]" +661,872,Simple anilines and phenols,"[$(c1([NX3]([#1,#6])[#1,#6])ccccc1),$(c1([OH1])ccccc1)]" +662,874,Vinyl ketones (Michael acceptors),[CX3]([!R])([!R])=[CX3][CX3](=[OX1])[!$([OH1])!$([OX2][CH2])!$([NH2])!$([CX2]#[NX1])!a] +663,875,Metals,[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53] +664,879,Non-organic chemistry atoms,[!#6!#1!#7!#8!#9!#17!#35!#53!#15!#14!#16] +665,880,Atoms not supported in ALOGPS program,[!#1!#6!#7!#8!#16!#15!#9!#17!#35!#53] +666,881,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F) +667,885,Carbonyl compouns: aldehydes or ketones,"[$([H][CX3]([#1,#6])=[OX1]),$([#6&!$(C#N)][CX3](=[OX1])[#6&!$(C#N)])]" +668,888,Thiocarbonyl compounds: thioaldehydes or thioketones,"[$([#1,#6][#6X3](=[SX1])[#1,#6]),$([#6]=[CX2]=[Sv2X1])]" +669,889,Thioaldehydes,"[#1][CX3]([#1,#6])=[SX1]" +670,890,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)] +671,892,Hydrazones,"[CX3]([#1,#6])([#1,#6])=[NX2][#7X3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]" +672,893,Semicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]" +673,894,Thiosemicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]" +674,895,Oximes,"[#1,#6][CX3]([#1,#6])=[NX2][OH1]" +675,896,Oxime ethers,"[#1,#6][CX3]([#1,#6])=[NX2][OX2][#6&!$([CX3]=[OX1,SX1,NX2])]" +676,898,Ketene acetal derivatives,"[#1,#6][CX3]([#1,#6])=[CX3]([!#6!#1])[!#6!#1]" +677,899,Carbonyl hydrates,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OH1]" +678,900,Hemiacetals / Hemiketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]" +679,901,Acetals / Ketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]" +680,902,Hemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,*])[#1,*]" +681,904,Thiohemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[NX3]([#1,*])[#1,*]" +682,905,Thioacetals / Thioketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[SX2,OX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)]" +683,907,Enols,"[CX3]([#1,#6])([#1,#6])=[CX3]([OH1])[#1,#6]" +684,908,Enolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([OX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]" +685,909,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]" +686,910,Alcohols,"[$([CX4][OH1])&!$(C([OH1])[#7,#8,#15,#16,F,Cl,Br,I])]" +687,911,Primary alcohols,"[$([#6][CH2][OH1]),$([CH3][OH1])]" +688,912,Secondary alcohols,[OH1][CX4H1]([#6])[#6] +689,913,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6] +690,914,"1,2-Diols","[CX4]([OH1])([#1,#6])([#1,#6])[CX4]([OH1])([#1,#6])([#1,#6])" +691,915,"1,2-Aminoalcohols","[CX4]([#1,#6])([#1,#6])([OH1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([CX4][CX4][OH1])[#6&!$([CX3]=[OX1,SX1,NX2,C])])]" +692,916,Phenols,c[OH1] +693,917,Diphenols,"[$(c([OH1])c([OH1])),$(c([OH1])[aR1]c([OH1])),$(c1([OH1])aac([OH1])aa1)]" +694,918,Enediols,"[CX3]([#1,#6])([OH1])=[CX3]([#1,#6])([OH1])" +695,920,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]" +696,921,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c" +697,922,Diarylethers,c[OX2&!$([OX2r3])]c +698,926,Hydroperoxides,"[#1,#6][OX2][OX2H1]" +699,927,Hydrazine derivatives,"[$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])][$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])]" +700,930,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]" +701,931,Primary aromatic amines,[NX3H2]c +702,932,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]" +703,933,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]" +704,934,Secondary aromatic amines,[NX3H1](c)c +705,935,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]" +706,936,Tertiary mixed amines (aryl alkyl),"c[NX3]([CX4&!$([CX4]([NX3])[O,N,S,P])])[c,CX4&!$([CX4]([NX3]c)[O,S,N,P])]" +707,938,Quaternary ammonium salts,"[NX4,NX4+]([#6])([#6])([#6])[#6]" +708,940,"Halogen derivatives (alkyl, alkenyl, aryl)","[CX4,CX3,c;!$([#6]=[OX1])][F,Cl,Br,I]" +709,945,Aryl fluorides,aF +710,946,Aryl chlorides,aCl +711,947,Aryl bromides,aBr +712,948,Aryl iodides,aI +713,950,Organolithium compounds,[Li][#6] +714,951,Organomagnesium compounds,[Mg][#6] +715,952,Carboxylic acid derivatives,"[#1,#6][CX3](=[OX1])[!#1!#6!$([SH1,SX2])]" +716,954,Carboxylic acid salts,"[#1,#6][CX3](=[OX1])[OX1-]" +717,957,Carboxylic acid amides,"[#1,#6][CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]" +718,958,Carboxylic acid primary amides,"[#1,#6][CX3](=[OX1])[NX3H2]" +719,959,Carboxylic acid secondary amides,"[#1,#6][CX3](=[OX1])[NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])]" +720,960,Carboxylic acid tertiary amides,"[#1,#6][CX3](=[OX1])[NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]" +721,961,Lactams,"[#6R][CX3R](=[OX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]" +722,962,Carboxylic acid hydrazides,"[$([#6,#1][#6X3](=[OX1])[#7X3&!$([#7X3]([*]=[OX1,SX1])[#7X3]([*]=[OX1,SX1]))][#7X3]),$(C1(=O)[NX3][NX3]C(=O)cc1)]" +723,963,Carboxylic acid azides,"[#1,#6][CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]" +724,964,Hydroxamic acids,"[#1,#6][CX3](=[OX1])[NX3][OH1]" +725,965,Carboxylic acid amidines,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,N])]" +726,966,Carboxylic acid amidrazones,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]" +727,967,Nitriles,"[#1,#6&!$([CX3]=[OX1,SX1])][CX2]#[NX1]" +728,969,Acyl fluorides,"[#1,#6][CX3](=[OX1])F" +729,970,Acyl chlorides,"[#1,#6][CX3](=[OX1])Cl" +730,971,Acyl bromides,"[#1,#6][CX3](=[OX1])Br" +731,972,Acyl iodides,"[#1,#6][CX3](=[OX1])I" +732,973,Acyl cyanides,"[#1,#6][CX3](=[OX1])[CX2]#[NX1]" +733,974,Imido esters,"[#1,#6][CX3](=[NX2][#1,#6])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]" +734,976,Thiocarboxylic acid derivatives,"[$([#1,#6][CX3](=[SX1])[!#1!#6]),$([#1,#6][CX3](=[OX1])[SX2])]" +735,977,Thiocarboxylic acids,"[$([#1,#6][CX3](=[SX1])[OH1,SH1]),$([#1,#6][CX3](=[OX1])[SH1])]" +736,978,Thiocarboxylic acid esters,"[$([#1,#6][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#1,#6][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]" +737,979,Thiolactones,"[$([#6R][CX3R](=[SX1])[OX2R,SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])]),$([#6R][CX3R](=[OX1])[SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])])]" +738,980,Thiocarboxylic acid amides,"[#1,#6][CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]" +739,981,Thiolactams,"[#6R][CX3R](=[SX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]" +740,982,Imidothioesters,"[#1,#6][CX3](=[NX2][#1,#6])[SX2][C&!$([CX3]=[OX1,SX1,NX2])]" +741,983,Oxohetarenes,"[$(c(=[OX1])[$(n[#1,#6]),o,s]),$(c(=[OX1])a[$(n[#1,#6]),o,s]),$(c(=[OX1])aa[$(n[#1,#6]),o,s]),$(c(=[OX1])aaa[$(n[#1,#6]),o,s])]" +742,984,Thioxohetarenes,"[$(c(=[SX1])[$(n[#1,#6]),o,s]),$(c(=[SX1])a[$(n[#1,#6]),o,s]),$(c(=[SX1])aa[$(n[#1,#6]),o,s]),$(c(=[SX1])aaa[$(n[#1,#6]),o,s])]" +743,985,Iminohetarenes,"[$(c(=N)[$(n[#1,#6]),o,s]),$(c(=N)a[$(n[#1,#6]),o,s]),$(c(=N)aa[$(n[#1,#6]),o,s]),$(c(=N)aaa[$(n[#1,#6]),o,s])]" +744,986,Orthocarboxylic acid derivatives,"[CX4&!$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]))]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])([!#1!#6])([!#1!#6])[!#1!#6]" +745,987,Carboxylic acid orthoesters,"[#1,#6][CX4]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]" +746,988,Carboxylic acid amide acetals,"[CH1,$([CX4][#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[NX3]([#1,*])[#1,*]" +747,990,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]) +748,991,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]) +749,992,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]) +750,993,CO2 derivative (general),"[$([Cv4X4]([!#1!#6])([!#1!#6])([!#1!#6])[!#1!#6]),$([CX3](=[!#1!#6])([!#1!#6])[!#1!#6]),$([CX2](=[!#1!#6])=[!#1!#6]),$([CX2](#[!#1!#6])[!#1!#6])]" +751,994,Carbonic acid derivatives,"[$([CX3](=[OX1])([!#1!#6])[!#1!#6])&!$([CX3](=[OX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5])]" +752,995,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]" +753,996,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]" +754,997,Carbonic acid ester halides,"[#6][OX2][CX3](=[OX1])[F,Cl,Br,I]" +755,998,Thiocarbonic acid derivatives,"[$([CX3](=[SX1])([!#1!#6])[!#1!#6])&!$([CX3](=[SX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5]),$([CX3](=[OX1])([!#1!#6])[SX2])&!$([CX3](=[OX1])([#7,#15,#5])[#8X2,#16X2,#7,#15,#5])]" +756,999,Thiocarbonic acid monoesters,"[$([OH1,SH1][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([OH1][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([SH1][CX3](=[SX1,OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]" +757,1000,Thiocarbonic acid diesters,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]" +758,1001,Thiocarbonic acid ester halides,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[F,Cl,Br,I]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[F,Cl,Br,I])]" +759,1002,Carbamic acid derivatives,"[NX3]([#1,*])([#1,*])[CX3](=[OX1])[!#1!#6!#16!$([Pv5])]" +760,1003,Carbamic acid,[OH1][CX3](=[OX1])[NX3] +761,1004,Carbamic acid esters (urethanes),"[#6][OX2][CX3](=[OX1])[NH2,NH1,NX3]" +762,1005,Carbamic acid halides,"[F,Cl,Br,I][CX3](=[OX1])[NX3]" +763,1006,Thiocarbamic acid derivatives,"[$([NX3&!$([NX3]([CX3]=[SX1])[CX3]=[OX1,SX1,NX2])][CX3](=[SX1])[!#1!#6!#7!$([Pv5])]),$([NX3&!$([NX3]([CX3]=[OX1])[CX3]=[OX1,SX1,NX2])][CX3](=[OX1])[SH1,SX2])]" +764,1007,Thiocarbamic acids,"[$([OH1,SH1][CX3](=[SX1])[NX3]),$([SH1][CX3](=[OX1])[NX3])]" +765,1008,Thiocarbamic acid esters,"[$([#6][OX2,SX2][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])]),$([#6][SX2][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])])]" +766,1009,Thiocarbamic acid halides,"[F,Cl,Br,I][CX3](=[SX1])[NX3]" +767,1011,Isoureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([OX2])=[NX2][#1,#6]" +768,1013,Isothioureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([S&!$([SX2]([CX3]=N)C=C)])=[NX2][#1,#6]" +769,1014,Guanidines,"N[CX3](=[NX2][#1,#6])N" +770,1015,Semicarbazides,"[$([NX3][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[OX1])[NX3]N=C)]" +771,1016,Thiosemicarbazides,"[$([NX3][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[SX1])[NX3]N=C)]" +772,1020,Isonitriles,"[#6&!$([CX3]=[OX1,SX1])][$([NX2+]#[CX1-]),$([NX2]#[CX1])]" +773,1030,Sulfuric acid derivatives,[!#1!#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6] +774,1031,Sulfuric acid,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])[OX2,O-]" +775,1032,Sulfuric acid monoesters,"[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OH1,O-]" +776,1033,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6] +777,1034,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N +778,1035,Sulfuric acid amides,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])N" +779,1036,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N +780,1037,Sulfuryl halides,"[!#1!#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]" +781,1038,Sulfonic acid derivatives,[#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6] +782,1039,Sulfonic acids,"[#6][Sv6X4](=[OX1])(=[OX1])[OH1,O-]" +783,1042,Sulfonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]" +784,1043,Sulfones,"[#6][Sv6X4](=[OX1,SX1,NX2])(=[OX1,SX1,NX2])[#6]" +785,1045,Sulfinic acid derivatives,[#6][Sv4X3](=[OX1])[!#1!#6] +786,1046,Sulfinic acids,"[#6][Sv4X3](=[OX1])[OH1,O-]" +787,1047,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6] +788,1048,Sulfinic acid halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]" +789,1049,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]" +790,1050,Sulfenic acid derivatives,[#6][Sv2X2][!#6!#1!S] +791,1051,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]" +792,1052,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]" +793,1053,Sulfenic acid halides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][F,Cl,Br,I]" +794,1054,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]" +795,1056,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]" +796,1057,Thiophenols,c[Sv2H1] +797,1058,Phosphoric acid derivatives,"[OX1]=[Pv5X4]([H,!#6!$([SX2])])([H,!#6!$([SX2])])[H,!#6!$([SX2])]" +798,1059,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O] +799,1060,Phosphoric acid esters,[OX1]=[Pv5X4]([OX2][#6])([!#6!$([SX2])])[!#6!$([SX2])] +800,1061,Phosphoric acid halides,"[OX1]=[Pv5X4]([F,Cl,Br,I])([!#6!$([SX2])])[!#6!$([SX2])]" +801,1062,Phosphoric acid amides,[OX1]=[Pv5X4]([NX3])([!#6!$([SX2])])[!#6!$([SX2])] +802,1063,Thiophosphoric acid derivatives,"[$([SX1]=[Pv5X4]([H,!#6])([H,!#6])[H,!#6]),$([OX1]=[Pv5X4]([SX2])([H,!#6])[H,!#6])]" +803,1064,Thiophosphoric acids,"[$([SX1]=[Pv5X4]([OH1,SH1])([O,S])[O,S]),$([OX1]=[Pv5X4]([SH1])([O,S])[O,S])]" +804,1065,Thiophosphoric acid esters,"[$([SX1]=[Pv5X4]([OX2,SX2][#6])([!#6])[!#6]),$([OX1]=[Pv5X4]([SX2][#6])([!#6])[!#6])]" +805,1066,Thiophosphoric acid halides,"[$([SX1]=[Pv5X4]([F,Cl,Br,I])([!#6])[!#6]),$([OX1]=[Pv5X4]([F,Cl,Br,I])([SX2,SH1])[!#6])]" +806,1067,Thiophosphoric acid amides,"[$([SX1]=[Pv5X4]([NX3])([!#6])[!#6]),$([OX1]=[Pv5X4]([NX3])([SX2,SH1])[!#6])]" +807,1068,Phosphonic acid derivatives,[OX1]=[Pv5X4]([#6])([!#6])[!#6] +808,1069,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O +809,1070,Phosphonic acid esters,[OX1]=[Pv5X4]([#6])([OX2][#6])[!#6] +810,1071,Phosphines,[Pv3X3]([#6])([#6])[#6] +811,1072,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6] +812,1073,Boronic acid derivatives,[Bv3X3]([#6])([!#6])[!#6] +813,1074,Boronic acids,"[BX3]([#6])([OH1,SH1])[O,S]" +814,1075,Boronic acid esters,"[BX3]([#6])([OX2][#6])[H,!#6]" +815,1077,Aromatic compounds,[a!r0] +816,1079,Heterocyclic compounds,[*R]~[*R&!#6]~[*R] +817,1080,Aromatic heterocyclic compounds,[a!#6!r0] +818,1081,α-Aminoacids,"[OH1][CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([#6])[#6])&!$([NH1](CC(=O)[OH1])[CX3]=[OX1,SX1])]" +819,1082,α-Hydroxyacids,"[OH1][CX3](=[OX1])[CX4]([OH1])[#1,#6]" +820,1083,"1,2-Diamines","[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])[CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])" +821,1084,"1,2-Dithiols","[CX4]([SH1])([#1,#6])([#1,#6])[CX4]([SH1])([#1,#6])([#1,#6])" +822,1085,"1,2-Aminothiols","[SH1][CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])" +823,1086,α-Oxoacids,"[OH1][CX3](=[OX1])[CX3](=[OX1])[#1,#6]" +824,1087,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3] +825,1088,Dithiophenols,"[$(c([SH1])c([SH1])),$(c([SH1])[aR1]c([SH1])),$(c1([SH1])aac([SH1])aa1)]" +826,1090,Aminothiophenols,"[$(c([SH1])c[NX3]([#1,#6])[#1,#6]),$(c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]),$(c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1)]" +827,1091,Aryl halides,"a[F,Cl,Br,I]" +828,1093,Primary amines,"[NX3H2][c,CX4&!$([CX4]([NH2])[O,N,S,P])]" +829,1094,Secondary amines,"[NX3H1]([c,CX4&!$([CX4]([NX3H1])[O,S,N,P])])[c,CX4&!$([CX4]([NX3H1])[O,S,N,P])]" +830,1095,Tertiary amines,"[NX3]([c,CX4&!$([CX4]([NX3])[O,S,N,P])])([c,CX4&!$([CX4]([NX3])[O,S,N,P])])[c,CX4&!$([CX4]([NX3])[O,S,N,P])]" +831,1098,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3] +832,1099,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3] +833,1102,Alkynyl halides,"[F,Cl,Br,I][CX2]#[CX2]" +834,1103,Benzyl halides,"a[CX4][F,Cl,Br,I]" +835,1104,Benzyl fluorides,a[CX4]F +836,1105,Benzyl chlorides,a[CX4]Cl +837,1106,Benzyl bromides,a[CX4]Br +838,1107,Benzyl iodides,a[CX4]I +839,1108,Alkali metals,"[#3,#11,#19,#37,#55,#87]" +840,1109,Alkaline earth metals,"[#4,#12,#20,#38,#56,#88]" +841,1110,Transition metals,"[#21,#22,#23,#24,#25,#26,#27,#28,#29,#30,#39,#40,#41,#42,#43,#44,#45,#46,#47,#48,#72,#73,#74,#75,#76,#77,#78,#79,#80,#104,#105,#106,#107,#108,#109,#110,#111,#112]" +842,1111,Lanthanoids,"[#57,#58,#59,#60,#61,#62,#63,#64,#65,#66,#67,#68,#69,#70,#71]" +843,1112,Actinoids,"[#89,#90,#91,#92,#93,#94,#95,#96,#97,#98,#99,#100,#101,#102,#103]" +844,1113,Post-transition metals,"[#13,#31,#49,#50,#81,#82,#83,#113,#114,#115,#116]" +845,1114,Metalloids,"[#5,#14,#32,#33,#51,#52,#84]" +846,1115,Nonmetals,"[#1,#6,#7,#8,#15,#16,#34,#9,#17,#35,#53,#85,#117,#2,#10,#18,#36,#54,#86,#118]" +847,1116,Halogens,"[#9,#17,#35,#53,#85,#117]" +848,1117,Noble gases,"[#2,#10,#18,#36,#54,#86,#118]" +849,1118,Chalcogens (oxygen group),"[#8,#16,#34,#52,#84,#116]" +850,1119,Pnictogens (nitrogen group),"[#7,#15,#33,#51,#83]" +851,1120,Tetragens (carbon group),"[#6,#14,#32,#50,#8,#114]" +852,1121,Thioenolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([SX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]" +853,1122,Thioenols,"[CX3]([#1,#6])([#1,#6])=[CX3]([SH1])[#1,#6]" +854,1123,Enethiodiols,"[CX3]([#1,#6])([SH1])=[CX3]([#1,#6])([SH1])" +855,1124,Alkynyl alcohols,[CX2]#[CX2][OH1] +856,1125,Alkynyl thiols,[CX2]#[CX2][SH1] +857,1127,Thioquinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[SX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1,SX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]" +858,1128,4halo_pyrimidine_2_6EWG,"n1c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[n;R1]c([F,Cl,Br,I])cc1([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])" +859,1129,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O +860,1130,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O +861,1131,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O +862,1132,sulphonyl_cyanide,S(=O)(=O)C#N +863,1133,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S +864,1134,2halo_pyrazine_5EWG,"[n;R1]1c([F,Cl,Br,I])[c;!$(c-N)]nc([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[c;!$(c-N)]1" +865,1135,activated_4mem_ring,"[#6]1~[$(C(=O)),$(S(=O))]~[O,S,N]~[$(C(=O)),$(S(=O))]1" +866,1136,halo_5heterocycle_bis_EWG,"[n,o,s]1c([$(S(=O)(=O)),$([F,Cl]),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])c([$(S(=O)(=O)),$([F,Cl]),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])nc1([Cl,Br,I])" +867,1137,hydroxamate_warhead,C([N;H1]([O;D1]))=O +868,1138,thiol_warhead,NC(C[S;D1])C(O)=O +869,1140,activated_vinyl_sulfonate,"O(-S(=O)(=O))C=[$(C(S(=O)(=O))),$(C(C(F)(F)(F))),$(C(C#N)),$(C(N(=O)(=O))),$(C([N+](=O)[O-])),$(C(C(=O)));!$(C(N))]" +870,1141,acyl_cyanide,C(=O)-C#N +871,1142,pentafluorophenylester,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F) +872,1143,vinyl_carbonyl_EWG,"[C;!R]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])=[C;!R]([C;!R](=O))([!$([#8]);!$([#7])])" +873,1144,4halo_pyrimidine_5EWG,"n1c[n;R1]c([F,Cl,Br,I])[#6]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])c1" +874,1145,alpha_halo_EWG,"[$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-])]-[CH,CH2]-[Cl,Br,I,$(O(S(=O)(=O)))]" +875,1146,2halo_pyrazine_3EWG,"[n;R1]1c([F,Cl,Br,I])c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])ncc1" +876,1147,boron_warhead,"[C,c]~[#5]" +877,1148,diamino_sulfide,"[N,n]~[S;!R;D2]~[N,n]" +878,1149,dicarbonyl_sulfonamide,"[$(N(-C(=O))(-C(=O))(-S(=O))),$(n([#6](=O))([#6](=O))([#16](=O)))]" +879,1150,acyl_imidazole,"[C;!$(C-N)](=O)n1[c;H1,$([#6]([*;!R]))]n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1" +880,1151,halo_phenolic_sulfonyl,"S(=O)Oc1c([Cl,F])[cH1,$(c[F,Cl])]c([F,Cl])[cH1,$(c[F,Cl])]c1([F,Cl])" +881,1152,oxaziridine,"C1~[O,S]~N1" +882,1153,sulf_D3_nitrogen,"[S;D3](-N)(-[c,C])(-[c,C])" +883,1154,2halo_pyridine_3EWG,"[n;R1]1[c;!$(c=O)]([F,Cl,Br,I])c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[c;!$(c-N)]c[c;!$(c-N)]1" +884,1155,2halo_pyridine_5EWG,"[n;R1]1[c;!$(c=O)]([F,Cl,Br,I])c[c;!$(c-N)]c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[c;!$(c=O);!$(c-N)]1" +885,1156,halo_olefin_bis_EWG,"C([Cl,Br,I,$(O(S(=O)(=O)))])=C([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])" +886,1157,hyperval_sulfur,"[$([#16&D3]),$([#16&D4])]=,:[#6]" +887,1158,ortho_hydroiminoquinone,c1c([N;D1])c([N;D1])c[cH1][cH1]1 +888,1159,keto_def_heterocycle,"[$(c([C;!R;!$(C-[N,O,S]);!$(C-[H])](=O))1naaaa1),$(c([C;!R;!$(C-[N,O,S]);!$(C-[H])](=O))1naa[n,s,o]1)]" +889,1160,trichloromethyl_ketone,[$(C(=O));!$(C-N);!$(C-O);!$(C-S)]C(Cl)(Cl)(Cl) +890,1161,phosphorus_phosphorus_bond,P~P +891,1162,monofluoroacetate,"[C;H2](F)C(=O)[O,N,S]" +892,1163,aryl_phosphonate,P(=O)-[O;!R]-a +893,1164,cyanohydrin,"[C;X4](-[OH,NH1,NH2,SH])(-C#N)" +894,1165,activated_vinyl_ester,"O=COC=[$(C(S(=O)(=O))),$(C(C(F)(F)(F))),$(C(C#N)),$(C(N(=O)(=O))),$(C([N+](=O)[O-])),$(C(C(=O)));!$(C(N))]" +895,1166,thio_hydroxamate,"[S;D2]([$(N(=C)),$(N(-S(=O)(=O))),$(N(-C(=O)))])" +896,1167,halo_imino,"C(=[#7])([Cl,Br,I,$(O(S(=O)(=O)))])" +897,1168,activated_acetylene,"[$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))]C#[C;!$(C-N);!$(C-n)]" +898,1169,acyl_pyrazole,"[C;!$(C-N)](=O)n1n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1" +899,1170,sulfonyl_heteroatom,"[!#6;!#1;!#11;!#19]O(S(=O)(=O)(-[C,c]))" +900,1171,triamide,"[$(N(-C(=O))(-C(=O))(-C(=O))),$(n([#6](=O))([#6](=O))([#6](=O)))]" +901,1173,acyclic_imide,"[C,c][C;!R](=O)[N;!R][C;!R](=O)[C,c]" +902,1174,4halo_pyridine_3EWG,"[n;R1]1[c;!$(c=O);!$(c-N)][#6]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])c([F,Cl,Br,I])c[c;!$(c=O);!$(c-N)]1" +903,1175,acyl_123_triazole,"[#7;R1]1=,:[#7;R1]-,:[#7;R1](-C(=O))-,:[#6]=,:[#6]1" +904,1176,alpha_dicarbonyl,C(=O)!@C(=O) +905,1177,trifluoroacetate_ester,C(F)(F)(F)C(=O)O +906,1178,perhalo_dicarbonyl_phenyl,"c1(C=O)c([Br,Cl,I])c([Br,Cl,I])c([Br,Cl,I])c([Br,Cl,I])c1(C=O)" +907,1179,trinitromethane_derivative,"C([$([N+](=O)[O-]),$(N(=O)=O)])([$([N+](=O)[O-]),$(N(=O)=O)])([$([N+](=O)[O-]),$(N(=O)=O)])" +908,1180,2halo_pyrimidine_5EWG,"[n;R1]1c([F,Cl,Br,I])ncc([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])c1" +909,1181,aldehyde,"[C,c][C;H1](=O)" +910,1182,alpha_halo_heteroatom_tert,"[N,n,O,S;!$(S(=O)(=O))]-C([Cl,Br,I,$(O(S(=O)(=O)))])(C)(C)" +911,1183,sulf_D2_nitrogen,[S;D2](-[N;!$(N(=C));!$(N(-S(=O)(=O)));!$(N(-C(=O)))]) +912,1184,2halo_pyridazine_5EWG,"[n;R1]1c([F,Cl,Br,I])ccc([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])n1" +913,1185,triflate,OS(=O)(=O)(C(F)(F)(F)) +914,1186,flavanoid,O=C2CC(a3aaaaa3)Oa1aaaaa12 +915,1187,non_ring_acetal,"[O,N,S;!$(S~O)]!@[C;H1;X4]!@[O,N,S;!$(S~O)]" +916,1188,rhodanine,C(=C)1SC(=S)NC(=O)1 +917,1189,azide,"[$(N#[N+]-[N-]),$([N-]=[N+]=N)]" +918,1190,NO_phosphonate,P(=O)ON +919,1191,azo_filter3,[N;!R]-[N;!R]-[N;!R] +920,1192,disulfonyliminoquinone,S(=O)(=O)N=C1C=CC(=NS(=O)(=O))C=C1 +921,1193,perchloro_cp,C1(Cl)(Cl)C(Cl)C(Cl)=C(Cl)C1(Cl) +922,1194,hetero_silyl,[Si]~[!#6] +923,1195,ortho_quinone,"[CH1,$(C(-[Cl,Br,I]))]1=CC(=[O,N,S;!R])C(=[O,N,S])C=[CH1,$(C(-[Cl,Br,I]))]1" +924,1196,meldrums_acid_deriv,O=C1OC(C)(C)OC(C1)=O +925,1197,sulfonyl_anhydride,"[$(C(=O)),$(S(=O)(=O))][O,S](S(=O)(=O))" +926,1198,tertiary_halide_sulfate,"[C;X4](-[Cl,Br,I,$(O(S(=O)(=O)[!$(N);!$([O&D1])]))])(-[c,C])(-[c,C])(-[c,C])" +927,1200,azo_filter4,a-N=N-[N;H2] +928,1201,trihalovinyl_heteroatom,"C(-[Cl,Br,I])(-[Cl,Br,I])=C(-[Cl,Br,I])(-[N,O,S])" +929,1202,sulf_D2_oxygen_D2,[S;D2][O;D2] +930,1203,acyl_activated_NO,"O=C(-[!N])O[$([#7;+]),$(N(C=[O,S,N])(C=[O,S,N]))]" +931,1204,azo_filter2,[N;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!r3;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!$(N-S(=O)(=O));!$(N-C=O)] +932,1205,para_hydroquinone,"a1[cH1]c([O,S;D1])[cH1]ac([O,S;D1])1" +933,1206,oxime,[$(C=N[O;D1]);!$(C=[N+])][#6][#6] +934,1207,non_ring_CH2O_acetal,"[O,N,S;!$(S~O)]!@[CH2]!@[O,S,N;!$(S~O)]" +935,1208,hydrazine,[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))]-[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))] +936,1209,isonitrile,[N+]#[C-] +937,1210,sulfite_sulfate_ester,"[C,c]OS(=O)O[C,c]" +938,1211,aziridine_diazirine,"[C,N]1~[C,N]~N~1" +939,1212,gte_3_COOH,C(=O)[O;D1].C(=O)[O;D1].C(=O)[O;D1] +940,1213,acyl_134_triazole,"[#7]1=,:[#6]-,:[#7](-C(=O)[H,!N])-,:[#6]=,:[#7]1" +941,1214,trifluoromethyl_ketone,[$(C(=O));!$(C-N);!$(C-O);!$(C-S)]C(F)(F)(F) +942,1215,para_nitrophenyl_ester,"c1(-O(-[C;!R](-[H,!N])(=[O,N;!R])))ccc([$(N(=O)(=O)),$([N+](=O)[O-])])cc1" +943,1216,phosphorus_sulfur_bond,P~S +944,1217,polyene,C=[C;!R][C;!R]=[C;!R][C;!R]=[C;!R] +945,1218,thiocarbonate,"SC(=O)[O,S]" +946,1220,azo_amino,[N]=[N;!R]-[N] +947,1221,secondary_halide_sulfate,"[CH;!$(C=C)][Cl,Br,I,$(O(S(=O)(=O)[!$(N);!$([O&D1])]))]" +948,1222,nitrone,[C;!R]=[N+][O;D1] +949,1223,trisub_bis_act_olefin,"[CH&!R;!$(C-N)]=C([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])" +950,1224,anhydride,"[$(C(=O)),$(C(=S))]-[O,S]-[$(C(=O)),$(C(=S)),$(C(=[N;!R])),$(C(=N(-[C;X4])))]" +951,1225,non_ring_ketal,"[O,N,S;!$(S~O)]!@[C;H0;X4](!@[O,N,S;!$(S~O)])(C)" +952,1226,triaryl_phosphine_oxide,P(=O)(a)(a)(a) +953,1227,betalactam_EWG,"C1(=O)~[#6]~[#6]N1([$(S(=O)(=O)[C,c,O&D2]),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O)[C,c,O&D2])])" +954,1228,HOBT_ester,"O=C(-[!N])O[$(nnn),$([#7]-[#7]=[#7])]" +955,1230,alpha_halo_amine,"[F,Cl,Br,I,$(O(S(=O)(=O)))]-[CH,CH2;!$(C(F)F)]-[N,n]" +956,1231,sulfonium,[S+;X3;$(S-C);!$(S-[O;D1])] +957,1232,azo_filter1,[N;!R]=[N;!R]-[N]=[*] +958,1233,CH2_S#O_3_ring,"[CH2]1[O,S]C1" +959,1234,polysulfide,[S;D2]-[S;D2]-[S;D2] +960,1235,acrylate,[CH2]=[C;!$(C-N);!$(C-O)]C(=O) +961,1236,four_nitriles,C#N.C#N.C#N.C#N +962,1238,primary_halide_sulfate,"[CH2][Cl,Br,I,$(O(S(=O)(=O)[!$(N);!$([O&D1])]))]" +963,1239,para_quinone,"[CH1,$(C(-[Cl,Br,I]))]1=[CH1,$(C(-[Cl,Br,I]))]C(=[O,N,S])[CH1,$(C(-[Cl,Br,I]))]=[CH1,$(C(-[Cl,Br,I]))]C1(=[O,N,S])" +964,1240,phosphorane,C=P +965,1241,activated_S#O_3_ring,"C1~[O,S]~[C,N,O,S]1[a,N,O,S]" +966,1242,thioester,"[S;!R;H0]C(=[S,O;!R])([!O;!S;!N])" +967,1243,gte_7_aliphatic_OH,C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1] +968,1244,bis_activated_aryl_ester,"O=[C,S]Oc1aaa([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O)O),$(C(=O)N)])aa([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O)O),$(C(=O)N)])1" +969,1245,ortho_nitrophenyl_carbonyl,"c1(-O-[C;!R](=[O,N;!R]))c([$(N(=O)(=O)),$([N+](=O)[O-])])cccc1" +970,1246,gte_2_free_phos,P([O;D1])=O.P([O;D1])=O +971,1247,benzidine_like,c([N;!+])1ccc(c2ccc([N;!+])cc2)cc1 +972,1248,activated_azo,"[N;!R]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])=[N;!R]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])" +973,1249,quat_N_acyl,"[N,n;+]!@C(=O)" +974,1250,aryl_thiocarbonyl,a-[S;X2;!R]-[C;!R](=O) +975,1251,hydrazothiourea,[N;!R]=NC(=S)N +976,1252,nitrosamine,N-[N;X2](=O) +977,1253,halo_phenolic_carbonyl,"C(=O)Oc1c([Cl,F])[cH1,$(c[F,Cl])]c([F,Cl])[cH1,$(c[F,Cl])]c1([F,Cl])" +978,1254,gte_8_CF2_or_CH2,"[CH2,CF2;R0][CH2,CF2;R0][CH2,CF2;R0][CH2,CF2;R0][CH2,CF2;R0][CH2,CF2;R0][CH2,CF2;R0][CH2,CF2;R0]" +979,1255,diazo_carbonyl,"[$(N=N=C~C=O),$(N#N-C~C=O)]" +980,1256,2halo_pyridazine_3EWG,"[n;R1]1c([F,Cl,Br,I])c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])ccn1" +981,1257,gte_10_carbon_sb_chain,[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R] +982,1258,beta_lactone,"[#6,#15,#16]1(=O)~[#6]~[#6]~[#8,#16]1" +983,1259,linear_polycyclic_aromatic_I,"[$(a12aaaaa1aa3a(aa(aaaa4)a4a3)a2),$(a12aaaaa1aa3a(aaa4a3aaaa4)a2),$(a12aaaaa1a(aa5)a3a(aaa4a3a5aaa4)a2)]" +984,1260,alpha_halo_carbonyl,"C(=O)([CH,CH2][Cl,Br,I,$(O(S(=O)(=O)))])" +985,1261,phosphorous_nitrogen_bond,"[#15]~[N,n]" +986,1262,gte_2_N_quats,"[N,n;H0;+;!$(N~O);!$(n~O)].[N,n;H0;+;!$(N~O);!$(n~O)]" +987,1263,betalactam,C1(=O)~[#6]~[#6]N1 +988,1264,peroxide,[#8]~[#8] +989,1265,paraquat_like,[#6]1[#6][#6]([#6]2[#6][#6][#7;+][#6][#6]2)[#6][#6][#7;+]1 +990,1266,perhalo_phenyl,"c1c([Br,Cl,I])c([Br,Cl,I])c([Br,Cl,I])c([Br,Cl,I])c1([Br,Cl,I])" +991,1267,phosphite,"[c,C]-[P;v3]" +992,1268,ortho_hydroquinone,"a1c([O,S;D1])c([O,S;D1])a[cH1][cH1]1" +993,1269,maleimide_etc,"[$([C;H1]),$(C(-[F,Cl,Br,I]))]1=[$([C;H1]),$(C(-[F,Cl,Br,I]))]C(=O)[N,O,S]C(=O)1" +994,1270,azo_aryl,c[N;!R;!+]=[N;!R;!+]-c +995,1271,bad_cations,"[C+,F+,Cl+,Br+,I+,Se+]" +996,1272,linear_polycyclic_aromatic_II,"[$(a12aaaa4a1a3a(aaaa3aa4)aa2),$(a12aaaaa1a3a(aaa4a3aaaa4)aa2),$(a1(a(aaaa4)a4a3a2aaaa3)a2aaaa1)]" +997,1273,quat_N_N,"[N,n;R;+]!@[N,n]" +998,1274,sulfonyl_halide,"S(=O)(=O)[F,Cl,Br,I]" +999,1275,gte_7_total_hal,"[Cl,Br,I].[Cl,Br,I].[Cl,Br,I].[Cl,Br,I].[Cl,Br,I].[Cl,Br,I].[Cl,Br,I]" +1000,1277,para_hydroiminoquinone,a1[cH1]c([N;D1])[cH1]ac([N;D1])1 +1001,1278,carbonyl_halide,"O=C[F,Cl,Br,I]" +1002,1279,carbodiimide_iso#thio#cyanate,"N=C=[N,O,S]" +1003,1280,phosphonium,[#15;+]~[!O] +1004,1281,gte_4_nitro,"[$([N+](=O)[O-]),$(N(=O)=O)].[$([N+](=O)[O-]),$(N(=O)=O)].[$([N+](=O)[O-]),$(N(=O)=O)].[$([N+](=O)[O-]),$(N(=O)=O)]" +1005,1282,gte_2_sulfonic_acid,"[C,c]S(=O)(=O)[O;D1].[C,c]S(=O)(=O)[O;D1]" +1006,1283,bis_keto_olefin,"CC(=O)[$([C&H1]),$(C-F),$(C-Cl),$(C-Br),$(C-I)]=[$([C&H1]),$(C-F),$(C-Cl),$(C-Br),$(C-I)]C(=O)C" +1007,1284,disulfide_acyclic,[S;!R;X2]-[S;!R;X2] +1008,1285,bad_boron,"[B-,BH2,BH3,$(B(F)(F))]" +1009,1286,thiopyrylium,"c1[S,s;+]cccc1" +1010,1287,gte_3_iodine,[#53].[#53].[#53] +1011,1288,polyhalo_phenol_b,"c1c([O;D1])c(-[Cl,Br,I])cc(-[Cl,Br,I])c1.c1c([O;D1])c(-[Cl,Br,I])cc(-[Cl,Br,I])c1" +1012,1289,branched_polycyclic_aromatic,a1(a2aa(a3aaaaa3)aa(a4aaaaa4)a2)aaaaa1 +1013,1290,gte_5_phenolic_OH,a[O;D1].a[O;D1].a[O;D1].a[O;D1].a[O;D1] +1014,1291,oxonium,"[o+,O+]" +1015,1292,halogen_heteroatom,"[!C;!c;!H][F,Cl,Br,I]" +1016,1293,diazonium,a[N+]#N +1017,1294,porphyrin,"[#6;r16,r17,r18]~[#6]1~[#6]~[#6]~[#6](~[#6])~[#7]1" +1018,1296,polyhalo_phenol_a,"c1c([O;D1])c(-[Cl,Br,I])c(-[Cl,Br,I])cc1.c1c([O;D1])c(-[Cl,Br,I])c(-[Cl,Br,I])cc1" +1019,1297,thio_xanthate,[S;!R]-[C;!R](=[S;!R])(-[S;!R]) +1020,1298,thiosulfoxide,"[C,c][S;X3](~O)-S" +1021,1299,polyhalo_phenol_c,"c1c([O;D1])ccc(-[Cl,Br,I])c(-[Cl,Br,I])1.c1c([O;D1])ccc(-[Cl,Br,I])c(-[Cl,Br,I])1" +1022,1300,quinone_methide,"[#6;!$([#6](-[N,O,S]))]1=[#6;!$([#6](-[N,O,S]))][#6](=[#6])[#6;!$([#6](-[N,O,S]))]=[#6;!$([#6](-[N,O,S]))][#6]1(=[O,N,S])" +1023,1301,polyhalo_phenol_d,"c(-[Cl,Br,I])1c([O;D1])c(-[Cl,Br,I])ccc1.c(-[Cl,Br,I])1c([O;D1])c(-[Cl,Br,I])ccc1" +1024,1302,3halo_pyridazine_2EWG,"[n;R1]1c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])c([F,Cl,Br,I])ccn1" +1025,1303,3halo_pyridazine_4EWG,"[n;R1]1cc([F,Cl,Br,I])[#6]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])cn1" +1026,1304,cyano_phosphonate,"P(O[A,a])(O[A,a])(=O)C#N" +1027,1305,double_trouble_warhead,NC(C[S;D1])C([N;H1]([O;D1]))=O +1028,1314,Anil_di_alk_C,"c1c(ccc(c1)N([CX4])[H,CX4])O[CX4]" +1029,1315,Anil_di_alk_D,"c1c(ccc(c1)[CX4][$([#8!H0]),$([#6]=[#6!H0]),$([#7][CX4])])[#7]([CX4])[CX4]" +1030,1316,Anil_di_alk_E,"[$([#6!H0][#7]([CH2,CH3])c1[cH]c([H,CH2,CH3])c([CH,CH2][C!H0])[cH][cH]1),$([#6!H0][#7]([CH2,CH3])c1[cH]c([H,CH2,CH3])c([CH3])[cH][cH]1)]" +1031,1317,Ene_five_het_A,C1(=C)C=N[!#1!#6]C1=[OX1] +1032,1318,Ene_six_het_A,[#6]1([#6](~[!#1!#6]~[#6][!#1!#6][#6]1=[!#1!#6])~[!#1!#6])=[#6!R!H0] +1033,1319,Hzone_phenol_A,c1ccc(c(c1)[#8!H0])[#6]=[#7][#7] +1034,1320,Quinone_A,"[!#1!#6]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[!#1!#6])-,:[#6]=,:[#6]1" +1035,1321,Azo_A,[N!R]=N +1036,1322,Imine_one_A,"[#6][#6](=[!#1!#6!R])[#6](=[!#1!#6!R])[#6,$(S(=O)=O)]" +1037,1323,Mannich_A,N[CX4]c1c([OH1])cccc1 +1038,1324,Ene_rhod_A,N1C(=S)SC(=C)C1=O +1039,1325,Hzone_phenol_B,c1(ccc(cc1)C=N[#7])[OH1] +1040,1326,Imine_one_isatin,[OX1]=C2C(=;!@N[#7])c3c(cccc3)N2 +1041,1327,Anil_di_alk_A,"[CH2,CH3]N([CH2,CH3])c1cc([H,CH2,CH3,$(O(c)[CH2][CH2,CH3])])c(-[#7])[cH]c1" +1042,1328,Anil_di_alk_B,c1c(ccc(c1)[#6]=[#6])[#7]([CX4])[CX4] +1043,1329,Pyrrole_A,"[#7]1(c2acccc2)-,:[#6]([CX4])=,:[#6]-,:[#6!H0]=,:[#6]1[CX4]" +1044,1330,Pyrrole_B,"[#7]1(c2acccc2)-,:[#6]([CX4])=,:[#6]-,:[#6H]=,:[#6]1cc" +1045,1331,Catechol_A,c1ccc(c(c1)[OH1])[OH1] +1046,1332,Ene_five_one_A,c2ccc1C(=[OX1])C(=C)C(=[OX1])c1c2 +1047,1333,Ene_five_one_B,"[cH]1[cH][cH][cH]c2[CH2]C(=[OX1])C(=C([CH2,CH3])[CH2,CH3])c12" +1048,1334,Ene_five_het_B,C1(=C)C(N=CS1)=O +1049,1335,Ene_five_het_C,C1(C(C=C[!#1!#6]1)=C)=[!#1!#6] +1050,1336,Ene_five_het_D,C1(=C)C(=[OX1])NNC1=[OX1] +1051,1337,Ene_five_het_E,NC=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2 +1052,1338,Ene_five_het_F,c1(ccccc1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)S2 +1053,1339,Ene_one_ene_A,C=!@C([!#1])-&@C(=!@[!#1!#6])-&@C(=!@C)[!#1] +1054,1340,Ene_one_ester,[#6][#6](=[#8])[#6!H0]=[#6]([#7!H0][#6])[#6](=[#8])[#8][#6] +1055,1341,Ene_one_A,a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])Nc2cc3c(cc2)nc(cc3)N([#6])[#6] +1056,1342,Ene_one_D,c([OH1])c-C(=[OX1])[C!H0]=C([#6])[#6] +1057,1343,Ene_one_hal,"[#6][#6]=[#6]([F,Cl,Br,I])[#6](=[OX1])[#6]" +1058,1344,Ene_cyano_A,[#6](C#[#7])(C#[#7])=Cc1ccccc1 +1059,1345,Ene_rhod_B,"[#16]1C(=O)NC(=O)C1=[#6!H0][$([#6]Br),$(c[cH]c([F,Cl,Br,I])cc[F,Cl,Br,I]),$(c[cH][cH]cS[CH2,CH3]),$(ccccccccccO[CH2,CH3]),$(c2c([CH2,CH3])n([CH2,CH3])c([CH2,CH3])c2)]" +1060,1346,Hzone_pipzn,[#6]N1[CH2][CH2]N([CH2][CH2]1)[#7]=[#6!H0]ca +1061,1347,Hzone_pyrrol,n1(C)[cH1][cH1][cH1]c1C=NN +1062,1348,Hzone_enamin,"[#7!H0][#7]=[#6][#6]([H,#6])=[#6]([#6])-!@[#7,#8&!H0]" +1063,1349,Hzone_anil_di_alk,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6H]=[#7][#7][$([#6](=O)[CH2]Scn),$([#6](=O)[CH2]aan),$([#6](=O)cc[OH1]),$(cn),$([CH2][#6!H0][OH1])])[cH][cH]1" +1064,1350,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2 +1065,1351,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1 +1066,1352,Keto_keto_beta_zone,"cc[N!H0]N=C([CH2,CH3])[CH2]C([CH2,CH3])=N[N!H0]cc" +1067,1353,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1] +1068,1354,Cyano_pyridone_A,"[#6]1(=[SX1])-,:[#7!H0]-,:*=,:*-,:*=,:[#6]1C#[NX1]" +1069,1355,Cyano_pyridone_B,"[#6]1(=,:[#6](-,:[#6](=O)-,:[#7]-,:[#6](=,:[#7]1)[!#1!#6])C#[#7])[#6]" +1070,1356,Cyano_imine_A,[N!H0]N=C(C#[NX1])C=[!#6&!R] +1071,1357,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1 +1072,1358,Cyano_cyano_A,"C(C#[NX1])(C#[NX1])C([$(C#[NX1]),$(C=N)])C#[NX1]" +1073,1359,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9 +1074,1360,Anil_no_alk,"c1([NH2])[cH][cH]c([#7,#8,CH2,CH3])[cH][cH]1" +1075,1361,Anil_di_alk_furan_A,"N([CH2,CH3])([CH2,CH3])c1oc(C=N[N!H0]C(=[!#1!#6]))[cH][cH]1" +1076,1362,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7] +1077,1363,Thiaz_ene_A,"C1([CH2,CH3,$(cc)])=C([H,CH2,CH3,$(C=O)])SC(N1([H,$([C!H0]),$(cc)]))=[#7!R]" +1078,1364,Thiaz_ene_B,"C1([$(NC(=[OX1])cc),NH2])=C(-!@C(=[OX1])N[CH2,CH3])SC(N1[$([CH2][CH]=[CH2]),$(cc)])=[SX1]" +1079,1365,Thio_carbonate_A,"[#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]" +1080,1366,Thiophene_amino_Aa,[NH2]c1sc([!#1])c([!#1])c1C=[OX1] +1081,1367,Thiophene_amino_Ab,"[H,CH2,CH3,$(cc)]c1sc([#7!H0][#6](=O)[#6])c(C(=O)[#8])c1[$(c2ccccc2),$(c3sccc3)]" +1082,1368,Thiophene_hydroxy,"[#16]1-,:[#6]=,:[#6]-,:[#6](=,:[#6]1)[OH1]" +1083,1369,Sulfonamide_A,"c1(c(c([cH]c([cH]1)[F,Cl,Br,I])[F,Cl,Br,I])[OH1])S(=[OX1])(=[OX1])N" +1084,1370,Sulfonamide_B,c1c(ccc(c1)[NH]S(=[OX1])=[OX1])[OH1] +1085,1371,Thio_ketone,"[#6]-,:[CX3](=[SX1])-,:[#6]" +1086,1373,Anthranil_one_A,"[$(c1c(c(ccc1)C(-cc)=[OX1])[NH&!$([NH][CX3]=[OX1])]),$(c1c(c(ccc1)C(-cc)=[OX1])[NH2])]" +1087,1374,Diazox_sulfon_A,"N(c1ccccc1)S(=[OX1])(=[OX1])c2c3n[o,s]nc3ccc2" +1088,1375,Dyes3A,"[#7v4,#7+](-,:[#6]=,:[#6])=,:[#6]-[CH]=CN([CX4])[#6]" +1089,1376,Dyes5A,"[CH2,CH3][#7](:,-[#6]:[#6])~[#6]-,:[#6]=,:[#6]-[#6]~[#6]:,-[#7]" +1090,1377,Rhod_sat_A,"[#7]1-,:[#6](=[#16])-,:[#16]-,:[#6X4]-,:[#6]1=[#8]" +1091,1378,Imine_one_fives,[#6]1(=[!#1!#6!R])[#6](=[OX1])[!#1!#6]*=[#6]1 +1092,1379,Imine_one_sixes,C1(C(=[OX1])NC(=[OX1])NC1(=[OX1]))=N +1093,1380,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4" +1094,1381,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4 +1095,1382,Thio_dibenzo,"[SX1]=[#6]1-,:[#6]=,:[#6]-,:[!#1!#6]-,:[#6]=,:[#6]1" +1096,1383,Het_65_A,"[OX1]=CC1=C2N=C([CH2,CH3])C=C([OH1])N2N=C1" +1097,1384,Het_6_tetrazine,"N~c1[n,$(c(N))][n,c!H0,$(c[N!H0])]c([N!H0,$([OX2][CH2,CH3])])nn1" +1098,1385,Imidazole_A,"[#7]1-,:[#6](-c2ccccc2)=,:[#6](-c3ccccc3)-,:[#7!H0]-,:[#6]1-ca" +1099,1386,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1 +1100,1387,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1 +1101,1388,Anisol_A,"c1(O[CH2,CH3])c([H,CH2,CH3])[cH]c(O[CH2,CH3])c([CH2][$([N!H0]C(=[OX1])[CH2][CH2][CH2,CH3]),$([C!H0]([CH2,CH3])[N!H0]C(=[SX1])[N!H0])])[cH]1" +1102,1389,Anisol_B,"[CH2,CH3](c4c([cH][cH]c([cH]4)[CH2][N!H0][CX4])O[CH2,CH3])" +1103,1390,Anthranil_acid_B,"c3cc(C(=[OX1])[N!H0]c4ccccc4C(=[OX1])[OH1])cc1c3C(=[OX1])N([CH2,CH3])C1=[OX1]" +1104,1391,Anthranil_acid_C,"[#6]1(=,:[#6]([NH2])-,:[#7](-c7ccccc7C(=[OX1])[OH1])-,:[#7]=,:[#6]1C=[OX1])[$(C#[NX1]),$(C=S)]" +1105,1392,Anthranil_acid_D,"c12ncccc1-,:[#6]([NH2])=,:[#6](C(=[OX1])~[OX1,O-])-,:[#16]2" +1106,1393,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1 +1107,1394,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1] +1108,1395,Anthranil_acid_G,"c1([cH][cH]c(O[CH2,CH3])[cH]c1(C(=[OX1])[OH1]))[N!H0]cc" +1109,1396,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc" +1110,1397,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]) +1111,1398,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc +1112,1399,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3 +1113,1400,Azulene,c1ccc4c(cc1)ccc4 +1114,1401,Anil_alk_A,"[CH2,CH3]Occ[CH2][N!H0]c1[cH]c2n[cH]n([#6!H0])c2[cH][cH]1" +1115,1402,Anil_alk_B,"[N!H0](c1[cH][cH]c([CH2,CH3])[cH][cH]1)[CH2][CH2]c2[cH][cH]c(O[CH2,CH3])[cH][cH]2" +1116,1403,Anil_alk_C,"[N!H0](c1ccccc1)C([#6])([#6])c2[cH][cH]c(O[CH2,CH3])[cH][cH]2" +1117,1404,Anil_alk_D,"[N!H0](c1[cH][cH]c([C!H0]([CH2,CH3])[CH2,CH3])[cH][cH]1)[CH2][CH2]N([CH2,CH3])[CH2,CH3]" +1118,1405,Anil_alk_thio,c1ccc2c(c1)C3=C(C([#6])([#6])N2)SSC3=* +1119,1406,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4] +1120,1407,Anil_di_alk_F,"c1c(ccc(N([H,CX4])([H,CX4]))c1)[CX4]c2ccc(cc2)N([H,CX4])([H,CX4])" +1121,1408,Anil_di_alk_J,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6!H0]=[#7][#7]=[#6]([#6])-cc)[cH][cH]1" +1122,1409,Anil_di_alk_I,"[cH]1c([N!H0]C(=[OX1])c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1" +1123,1410,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3 +1124,1411,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23 +1125,1412,Anil_di_alk_ene_B,"[CH2,CH3]N([CH2,CH3])C1=Cc2ccccc2[CH2]1" +1126,1413,Anil_di_alk_furan_B,"[CH2,CH3]N([CH2,CH3])c1[cH][cH]c(o1)[C!H0]=CC#[NX1]" +1127,1414,Anil_di_alk_indol,"c12[cH][cH]c(N([CH2,CH3])[CH2,CH3])[cH]c1-,:[#6](S(=[OX1])=[OX1])=,:[#6H]-,:[#7!H0]2" +1128,1415,Anil_no_alk_indol_A,"c12[cH][cH]c([NH2])[cH]c1[cH][cH]n2[CH2,CH3]" +1129,1416,Anil_NH_alk_A,"c1([N!H0][CH2,CH3])[cH][cH]c2c([cH]1)[#7!H0]-,:[#6](=[OX1])-,:[#7!H0]2" +1130,1417,Anil_NH_alk_B,[N!H0](c1ccacc1)c2ccc([N!H0][C!H0])cc2 +1131,1418,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0] +1132,1419,Anil_NH_alk_D,"[NH2]c1c([N!H0][C!H0]([#6])[C!H0][CH2,CH3])c[cH][cH][cH]1" +1133,1420,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc) +1134,1421,Anil_NH_no_alk_B,"[NH2]c1c([N!H0]S(=[OX1])=[OX1])[cH]c([N!H0][CH2,CH3])c([F,Cl,Br,I])[cH]1" +1135,1422,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2 +1136,1423,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1 +1137,1424,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12 +1138,1425,Anil_OC_alk_A,"[cH]1[cH][cH]c2c([cH]1)c3c(o2)[cH]c([N!H0][CH2,CH3])c(O[CH2,CH3])[cH]3" +1139,1426,Anil_OC_alk_B,"c2ccccc2N1C(=[OX1])C([N!H0]c2ccc(O[CH2,CH3])cc2)=C([F,Cl,Br,I])C1=[OX1]" +1140,1427,Anil_OC_alk_C,"[H,CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2]c2nccn2" +1141,1428,Anil_OC_alk_D,"[CH2,CH3]Oc1[cH][cH]c([CH2,CH3])[cH]c1[NH][CH2]c2c([CH2,CH3,$(O[CH2,CH3])])cccc2" +1142,1429,Anil_OC_alk_E,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2][C!H0]([OH1])[CH2,CH3]" +1143,1430,Anil_OC_alk_F,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][C!H0]([#16])C=[OX1]" +1144,1431,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4 +1145,1432,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc +1146,1433,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1" +1147,1434,Anil_no_alk_B,"[NH2]c1c(n2cccc2)[cH]c([CH2,CH3])c([CH2,CH3])[cH]1" +1148,1435,Anil_no_alk_D,"n1c([NH2])c([CH2,CH3])[cH]c([CH2,CH3])c1[NH2]" +1149,1436,Anil_no_alk_C,"[NH2]c1[cH][cH]c([cH][cH]1)-c2[cH]c(C=[OX1])c([CH2,CH3])o2" +1150,1437,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2 +1151,1438,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0] +1152,1439,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8 +1153,1440,Hzone_acyl_misc_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C(=[OX1])[N!H0]N=C([H,CH2,CH3])c2cc(*-*-*c3occc3)ccc2" +1154,1441,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2 +1155,1442,Hzone_thiophene_A,"[cH]2[cH][cH][cH]c1c2c([C!H0]=N[N!H0]([$(c3nc[cH]s3),$(c[cH][cH]),$(cncncn),$(cnnnn)]))c([H,$([OH1]),CH2,CH3])[a!c]1" +1156,1443,Hzone_thiophene_B,"c1(s[cH][cH]c1[H,CH2,CH3])[C!H0]=N[N!H0]c2ccccc2" +1157,1444,Hzone_phenone,"C(c1[cH]cc([H,CX4])[cH][cH]1)(c2[cH][cH]c([H,Cl])[cH][cH]2)=[$(NO[CH2][CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(NO[CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(N[N!H0]C(=[NH1])[NH2]),$([#6!H0][#7])]" +1158,1445,Hzone_furan_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[N!H0]c2nccs2" +1159,1446,Hzone_furan_B,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[NH]c2ccncc2" +1160,1447,Hzone_furan_C,c1ccccc1N(c2ccccc2)N=[C!H0]c3ac([cH][cH]3)-c4cc(C(=[OX1])[OH1])ccc4 +1161,1448,Hzone_furan_E,[OH1]C(=[OX1])c1cc(ccc1)-cacC=N[N!H0]C(=[OX1])[CH2][#8] +1162,1449,Hzone_naphth_A,"[cH]1[cH][cH]c2[cH][cH]c(C=N[N!H0][$(cc),$(C=[SX1])])[cH]c2c1" +1163,1450,Hzone_acid_A,"[cH]1[cH]c(O[CH2,CH3])[cH]c2C(=N[N!H0]c4[cH][cH]c(C(=[OX1])[OH1])[cH][cH]4)c3[cH]c(O[CH2,CH3])[cH][cH]c3c12" +1164,1451,Hzone_acid_D,[OH1]C(=[OX1])c1ccc(cc1)NN=[C!H0]c2ac([cH][cH]2)-c3ccccc3 +1165,1452,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1] +1166,1453,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1] +1167,1454,Het_5_C,"N1=C(c2ccccc2)[CH2]C([OH1])([CX4](F)(F)F)N1[$(cccccc),$(C(=S)cccccc)]" +1168,1455,Het_5_D,"N1(c2ccccc2)N=C([CH2,CH3])[C!H0](S[#6])C1=[OX1]" +1169,1456,Het_5_E,"N1(c2cccc3ccccc23)N=C([CH2,CH3])[CH2]C1=[OX1]" +1170,1457,Het_5_ene,"C1(=[OX1])C(=C([CH2,CH3])[N!H0][CH2][CH2][CH2,CH3])N=C(c2ccccc2)O1" +1171,1458,Het_5_inium,"[#7]1(c2ccccc2)[#6!H0]=[#7+,#7v4](c3ccccc3)[#6](=Nc4ccccc4)N1" +1172,1459,Het_5_pyrazole_OH,"n1(c2[cH][cH][cH][cH][cH]2)nc([CX4])c([H,C!H0])c1[OH1]" +1173,1460,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1" +1174,1461,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2 +1175,1462,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2 +1176,1463,Het_6_pyridone_NH2,[OH1]c2nc([NH2])acc2[CH2]C(=[OX1])[#8] +1177,1464,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1 +1178,1465,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0] +1179,1466,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12 +1180,1467,Het_65_B,a1a3a(aaa1)[N!H0]N(C3=O)[#6] +1181,1468,Het_65_C,"C1=CC=CC2=NC([$(C([!#1])=[C!H0]cc),$(coc)])=C(Ncc)N12" +1182,1469,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0] +1183,1470,Het_65_F,"[#16]1-,:[#6]2:[#6](-,:[#6]([CH2,CH3])=,:[#6]1[CH2,CH3])c(ncn2)NN=C[#6]3=,:[#6]-,:[#6]=,:[#6]-,:[#8]3" +1184,1471,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]" +1185,1472,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]" +1186,1473,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc +1187,1474,Het_65_J,"o1c([#6](~[#8])~[#8])cc2[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c12" +1188,1475,Het_65_K,N1=NNN=C2C=CC=C12 +1189,1476,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]" +1190,1477,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1 +1191,1478,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1 +1192,1479,Het_65_pyridone_A,"c1([CH2][CH2,CH3])c([CH2,CH3])c2C(=[!#1!#6X1])N([C!H0][$(C(=O)O),$(cc)])C([H,$(S(C)[CH2,CH3])])=Nc2[a&!c;X2]1" +1193,1480,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2" +1194,1481,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2 +1195,1482,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1] +1196,1483,Het_66_B,"c1ccc4c(c1)nc(nc4)[N!H0]C2=NC(C=C[N!H0]2)([CH2,CH3])[CH2,CH3]" +1197,1484,Het_66_C,c1ccc2nc([C!H0]=C([OH1])[#6])c([C!H0]=C([OH1])[#6])nc2a1 +1198,1485,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc +1199,1486,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1] +1200,1487,Het_66_anisole,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0]c2c3c(O[CH2,CH3])ccc(O[CH2,CH3])c3ncc2" +1201,1488,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2 +1202,1489,Het_465_misc,c1c4CCc4cc2OCOc12 +1203,1490,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1] +1204,1491,Het_565_indole,"[#6!H0]1=,:[#6!H0]-,:[#7]([CH2,CH3])c7c1c9[#6!H0]=,:[#6!H0]-,:[#7](c9c(c7O[CH2,CH3])O[CH2,CH3])[CH2,CH3]" +1205,1492,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2" +1206,1493,Het_666_B,"c1cccc9c1Oc2c(N9[CH2][CH2,CH3])cccc2" +1207,1494,Het_666_C,"c13cc2ccccc2cc1-,:[#7]([CH2,CH3])-,:[#6](=[OX1])-,:[#6](-cc[N!H0][CH2,CH3])=,:[#7]3" +1208,1495,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5 +1209,1496,Het_pyridiniums_B,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:*2=,:[#6]1-,:*=,:[#7+,#7v4](~cc)-,:*=,:[#6]2[H,*]" +1210,1497,Het_pyridiniums_C,"[#6]1~[#6]~[#6]~[#7+,#7v4]2~[#6](~[#7]1)~[#6]3~[#6]~[#6]~[#6]~[#7](-cc)~[#6]3~[#7]2" +1211,1498,Het_thio_5_A,"[CH2,CH3][SX2]c1n(-!@[CH2,CH3])c(-c2ccccc2)[cH]n1" +1212,1499,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1 +1213,1500,Het_thio_5_C,"[SX1]=[#6]1-,:[#7!H0]-,:[#7]=,:[#6](c2[cH][cH]c(O[CH2,CH3])[cH][cH]2)-,:[#8]1" +1214,1501,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1 +1215,1502,Het_thio_5_imine_B,"N1([CH2,CH3])C(=S)N(-cc)C(=N-cc)C1=N-cc" +1216,1503,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc +1217,1504,Het_thio_6_ene,c1cN=CC(=CN[#6])S1 +1218,1505,Het_thio_6_furan,"[CH2,CH3][SX2]c1nc(-c2o[cH][cH][cH]2)c(-c3o[cH][cH][cH]3)nn1" +1219,1506,Het_thio_65_A,"[#7]1=,:[#6]([SX2][CH2,CH3])-,:[#7]=,:[#7]-,:[#6]2=,:[#6]1-,:[#6]([CH2,CH3])=,:[#7]-,:[#7]2-c3cccccc3" +1220,1507,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]" +1221,1508,Het_thio_65_C,"n1c2ccccc2n([CH2,CH3])c1S[CH2]C(=[OX1])[N!H0]N=[C!H0][C!H0]=[C!H0]" +1222,1509,Het_thio_65_D,"c1(S[CH2]C(=[OX1])[NH]-cc)nc2[cH]c([F,Cl,Br,I])c[cH]c2[nH]1" +1223,1510,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2 +1224,1511,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2" +1225,1512,Het_thio_67_A,"[CH2,CH3][SX2]c1nc2OC=Ncc-c2nn1" +1226,1513,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3 +1227,1514,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1 +1228,1515,Het_thio_656c,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]2-,:[#7+,#7v4]=,:[#6]3-,:[#7](N=C(c5ccccc5)[CX4]S3)-,:[#6]12" +1229,1516,Het_thio_665,"c1ccc7c(c1)NC3=C(S7)SC(=C3)[CH2,CH3]" +1230,1517,Het_thio_666_A,"[cH]1[cH][cH][cH]c5N([H,CH3,$([CH2][C!H0])])c7c(~[H,$([N!H0][CX4]),$(cc)])c(~[H,$(cc)])c([H,NH2,$([OX2][CX4])])[cH]c7Sc15" +1231,1518,Het_thio_676_A,"c1ccc4c(c1)Sc8[cH][cH]c([cH]c8C(C4)N([H,CX4])([H,CX4]))[H,#8,#16X2,CX4,$(N([H,CX4])[H,CX4])]" +1232,1519,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13 +1233,1520,Het_thio_pyr_A,"n1c(S[C!H0])c(C#[NX1])c(c2ccc(O[Ch2,CH3])cc2)[cH]c1(cc)" +1234,1521,Het_thio_N_5A,N=C1N=CNS1 +1235,1522,Het_thio_N_5B,"[#6]1~[#6](~[#7]~[#7]~[#6](~[CH2,CH3])~[CH2,CH3])~[#7]~[#16]~[#6]1" +1236,1523,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2" +1237,1524,Het_thio_N_55,[C!H0]c1nn(c3ccccc3)s2[a!c]acc12 +1238,1525,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1 +1239,1526,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1 +1240,1527,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1 +1241,1528,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC +1242,1529,Styrene_B,"c1ccc4c(c1)[SX2,CX4]c8ccc(cc8C4=CC)[H,Cl,CX4]" +1243,1530,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C" +1244,1531,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6] +1245,1532,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc +1246,1533,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1] +1247,1534,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN +1248,1535,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S +1249,1536,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6] +1250,1537,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3 +1251,1538,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2" +1252,1539,Ene_five_het_G,"C1(=[OX1])C(=[C!H0][$(c2ccccc2),$(c2ccc[a!c]2)])N=C(aaa)[#16,$(Naa)]1" +1253,1540,Ene_five_het_H,N1=CC(C(N1)=S)=C +1254,1541,Ene_five_het_I,c1(ccco1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2 +1255,1542,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]" +1256,1543,Ene_five_het_K,"[#7]1([#6])-,:[#6H]=,:[#6H]-,:[#6H]=,:[#6]1([CH]=C2C(=[OX1])[!#6]C=,:*2)" +1257,1544,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1 +1258,1545,Ene_five_het_M,"C1=,:C[O,S]C(=CC=[OX1])C1=[OX1]" +1259,1546,Ene_five_het_N,"C1(=[OX1])C(=[C!H0]c2cc([F,Cl,Br,I])ccc2O[CH2,CH3])N=C(S[CH2,CH3])S1" +1260,1547,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1" +1261,1548,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0] +1262,1549,Ene_six_het_D,[OX1]=C1NNC(aa)=NC1=[C!H0] +1263,1550,Ene_quin_methide,"aaC([H,$(C#[NX1])])=[#6]1-,:[#6]=,:[#6]-,:[#6](=[OX1,N!R])-,:[#6]=,:[#6]1" +1264,1551,Ene_rhod_C,"S1C(=Ncc)N([H,$([CH2][CH2]O),$(cc)])C(=[OX1])C1(=[C!H0][$(cccCl),$(c[a!c])])" +1265,1552,Ene_rhod_D,"S1C(=!@N[H,$([N!H0](N)cc)])N([H,$(cnccs)])C(=[OX1])C1=[C!H0]cc[Cl,$(O[C!H0])]" +1266,1553,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc +1267,1554,Ene_rhod_F,"n1ccc([C!H0]=C2C(=[OX1])NC(=[!#1!#6])N2)c1[CH2,CH3]" +1268,1555,Ene_rhod_G,[OH1][CX3](=[OX1])c1cccc(c1)cac[C!H0]=C2C(=[!#1!#6])NC(=[!#1!#6])[!#1!#6]2 +1269,1556,Ene_rhod_H,"N1=C([CH2,CH3])C(=[OX1])N=C2N1C(=[OX1])C(=[C!H0]cc)S2" +1270,1557,Ene_rhod_I,"N1([CH2,CH3])C(=S)[N!H0]C(=[C!H0]c2cc(Br)ccc2)C1(=O)" +1271,1558,Ene_rhod_J,"[CH2,CH3]N1C(=[#16,#7])[!#6]C(=[#6]2-,:[#6H]=,:[#6H]cc-,:[#7]2[CH2,CH3])C1=[OX1]" +1272,1559,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1 +1273,1560,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]) +1274,1561,Ene_misc_C,"c1ccc4c(c1)N(C(C=C4)([CH2,CH3])[CH2,CH3])C(=[OX1])[N!H0]c3ccc(c(c3)O[CH2,CH3])O[CH2,CH3]" +1275,1562,Ene_misc_D,"c12[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c1C([#6])=C([#6])S[CH2]2" +1276,1563,Ene_misc_E,"c1(O[CH2,CH3])c(O[CH2,CH3])[cH]c2C=C[C!H0]Sc2[cH]1" +1277,1564,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc +1278,1565,Dhp_amino_CN_A,"[NH2]C1=C(C#[NX1])[C!H0](cc)C([CH2,CH3])=C(C=C)O1" +1279,1566,Dhp_amino_CN_B,"[NX3H2,OX2H1]C1=C(C#[NX1])[C!H0](cc)c2c(n(C)nc2)O1" +1280,1567,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1" +1281,1568,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1 +1282,1569,Dhp_amino_CN_E,"[CH2,CH3][SX2]C1=C(C#[NX1])[C!H0](cc)C(C#[NX1])C(=O)N1" +1283,1570,Dhp_amino_CN_F,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](c2cccs2)-,:[#6](C(=[OX1])O[#6])=,:[#6]([CH2,CH3])-,:[#8]1" +1284,1571,Dhp_amino_CN_G,"[SX2]1C=C(C#[NX1])C([#6])(C=[OX1])C([$(C=[OX1]),$(C#[NX1])])=C1[NH2]" +1285,1572,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1 +1286,1573,Dhp_keto_A,"[#7]1([H,CX4])-,:[#6]=,:[#6](C(=[OX1])ccc)-,:[#6]([#6])-,:[#6]([$(C=[OX1]),$(C#[NX1])])=,:[#6]1[CH3]" +1287,1574,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1] +1288,1575,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]) +1289,1576,Сyano_keto_A,"[CH2,CH3][C!H0](C#[NX1])C(=[OX1])[#6]" +1290,1577,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1 +1291,1578,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2] +1292,1579,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc +1293,1580,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0] +1294,1581,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1 +1295,1582,Cyano_pyridone_C,"C1(C([CH2,CH3])=C(C#[NX1])C(~[#8])~[#7]~[#6]1(~[#8]))=[C!H0]cc" +1296,1583,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]" +1297,1584,Cyano_pyridone_E,"ac[#6]1=,:[#6!H0]-,:[#6](co)=,:[#6](C#[NX1])-,:[#6](=[OX1])-,:[#7!H0]1" +1298,1586,Cyano_pyridone_G,"N1(c2ccc(O[CH2,CH3])cc2)C(=[OX1])C(C#[NX1])=CC(n3cncc3)=N1" +1299,1587,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1] +1300,1588,Thio_aldehyd_A,"[#1,#6][C!H0](=[SX1])" +1301,1589,Thio_amide_A,"[#6!H0]1=,:[#6]-,:[#8]-,:[#6](=,:[#6!H0]1)C(=[SX1])N5[CH2][CH2]*[CH2][CH2]5" +1302,1590,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1 +1303,1591,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0] +1304,1592,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0] +1305,1593,Thio_amide_E,"c1cccnc1C(=S)[N!H0]c2ccccc2O[CH2,CH3]" +1306,1594,Thio_amide_F,acC(=S)[N!H0][N!H0]ca +1307,1595,Thio_ester_A,C1=C(SC(C=C1)=S)[#7] +1308,1596,Thio_ester_B,"ccC(=[SX1])[SX2][C!H0][CH2,CH3,$(cc)]" +1309,1597,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)" +1310,1598,Thio_ene_amine_A,"S=CC([CH2,CH3])=C([CH2,CH3])N([CH2,CH3])[CH2,CH3]" +1311,1599,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1] +1312,1600,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1] +1313,1601,Thio_pyridine_A,c1(nanc(c2o[cH][cH][cH]2)n1)S[CX4] +1314,1602,Thio_thiomorph_Z,"[OX1]=C(N3CCSCC3)c9c([cH][cH][cH][cH]9)S[CH2,CH3]" +1315,1603,Thio_urea_A,"c1c([N!H0][CX3](=[SX1])[N!H0][CH2][CH2][CH2]N([CH2,CH3])c2ccccc2)cccc1" +1316,1604,Thio_urea_B,"c1c([#7!H0]C(=S)[#7!H0][CH2][CH2][#7]([CH2,CH3])c2ccccc2)cccc1" +1317,1605,Thio_urea_C,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]C(=[OX1])c2a[a!c]cc2 +1318,1606,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2 +1319,1607,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1 +1320,1608,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1 +1321,1609,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]" +1322,1610,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1" +1323,1611,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2 +1324,1612,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0] +1325,1613,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1" +1326,1614,Thio_urea_L,[CX4][SX2]C(=N-aaaa)[N!H0]N=[#6] +1327,1615,Thio_urea_M,"cc[#7]([CH2,CH3])[CH2][CH2][CH2][#7!H0]C(=S)[#7!H0]c1c([F,Cl,Br,I])[cH]c([CH2,CH3])[cH][cH]1" +1328,1616,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2 +1329,1617,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1 +1330,1618,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2" +1331,1619,Thio_urea_Q,"[cH]1[cH][cH][cH]c2[cH][cH][cH]c(c12)C([CH2,CH3])=N[N!H0]C(=S)[N!H0]ccc" +1332,1620,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1] +1333,1621,Thio_carbam_A,"[CH2,CH3]SC(=S)[N!H0][CH2]-cc" +1334,1622,Thio_carbam_ene,S1C(=S)NC=C[CX4]1 +1335,1623,Thio_carbonate_B,"[OX1]=[#6]1-,:[#16]c2cccc(O[CH2,CH3])c2-,:[#8]1" +1336,1624,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc) +1337,1625,Thio_imine_ium,"[CX4][#7+,#7v4]([CX4][OH1])=CS[C!H0]" +1338,1626,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1" +1339,1627,Thiophene_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=CC(=[OX1])c1c([SX2])sc([$(C#[NX1]),$(C=[OX1])])c1" +1340,1628,Thiophene_D,"s1[cH][cH]c(O[CH2,CH3])c1C(=[OX1])[N!H0][N!H0]" +1341,1629,Thiophene_E,"c1(sc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])C(=[OX1])[NH]c2nccs2" +1342,1630,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]) +1343,1631,Thiophene_amino_B,"c2ccccc2[#7!H0]c1sc([$([#6]=[#8]),$(C#[#7]),$([#6]([#8!H0])=[#6])])c([#7])c1[$(C#[#7]),$([#6](n)n)]" +1344,1632,Thiophene_amino_C,"[C!H0][CH2]c1sc([N!H0]C(=[OX1])CCC=[OX1])c([$(C(=[OX1])O),$(C#[NX1])])c1[CH2,CH3]" +1345,1633,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]) +1346,1634,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2" +1347,1635,Thiophene_amino_F,[NH2]c1sc([NH]C(=[OX1])c3ccccc3)c(C#[NX1])c1c2aaaaa2 +1348,1636,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1 +1349,1637,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc +1350,1638,Keto_naphthol_A,"[#6]C(=[OX1])c1cccc2cccc([OH1,NH2])c12" +1351,1639,Keto_thiophene,"c1(sc2ccccc2c1([CH2,CH3]))C(=[OX1])[CH2][CH2,CH3]" +1352,1640,Keto_phenone_A,c1cccc5c1C(c8c5nacc8)=[OX1] +1353,1641,Keto_phenone_B,c1cccc5c1C(C8C5=N[!#1!#6]=CC8)=[OX1] +1354,1642,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1] +1355,1643,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4 +1356,1644,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1 +1357,1645,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1] +1358,1646,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1] +1359,1647,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6] +1360,1648,Keto_keto_beta_F,"[CH2,CH3]C([OH1])=C(C(=[OX1])[CH2,CH3])[C!H0]C#C" +1361,1649,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7 +1362,1650,Thiaz_ene_C,"[#6]1([F,Cl,Br,I,$([#7v4R,#7v4R+](=,:[#6R])-,:[#6R])])=,:[#6](-!@C=N)-,:[#16]-,:[#6](=[OX1])-,:[#7]1" +1363,1651,Acyl_het_A,"[#7v4,#7+](=,:*-,:*=,:*)-,:*=O" +1364,1652,Anil_di_alk_G,"[CX4]N([CX4])c1[cH][cH]c([#6]2=,:[#7]-,:[#6]=,:[#6]-,:*2)[cH][cH]1" +1365,1653,Anil_di_alk_H,"[cH]1c([N!H0]S(=[OX1])(=[OX1])c2caccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1" +1366,1654,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1 +1367,1655,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3 +1368,1656,Anil_di_alk_O,"[cH]1c([N!H0]C(=S)[N!H0]c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1" +1369,1657,Anil_di_alk_P,"[CH2,CH3]N([CH2,CH3])c1cc2nc(S[CH2,CH3])sc2cc1" +1370,1658,Anil_di_alk_ene_A,"[CH2,CH3]N([CH2,CH3])C1=[C!H0]c2ccccc2[SX2]c3ccccc13" +1371,1659,Anil_di_alk_dhp,"N1C=C(C=[OX1])C(-c3ccc(N([CH2,CH3])[CH2,CH3])cc3)C2=C1(~[#7]~[#6](~[#16])~[#7]~[#6]2~[#7])" +1372,1660,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2 +1373,1661,Anil_di_alk_coum,"c2ccccc2N([C!H0])[C!H0][C!H0][C!H0][N!H0]C(=[OX1])[#6]1-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6](=[OX1])-,:[#8]-,:[#6]([CH2,CH3])=,:1" +1374,1662,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4 +1375,1663,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1] +1376,1664,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1 +1377,1665,Ene_one_amide_A,"c1ccccc1[C!H0]NC(=[OX1])C([N!H0][CH2,CH3])=[C!H0]C(=[OX1])c2ccc(O[CH2,CH3])cc2" +1378,1666,Ene_one_amide_B,"c13ccc2ccccc2c1[C!H0][CX4]NC3=[C!H0]C(=[OX1])N([CH2,CH3])[CH2,CH3]" +1379,1667,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1] +1380,1668,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1] +1381,1669,Ene_one_yne_A,C#CC(=[OX1])C#C +1382,1670,Imine_one_B,"[N!H0](c1ccccc1)N=C(C(=[OX1])[CH2,CH3])[N!H0][$([N!H0]),$(cc)]" +1383,1671,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1] +1384,1672,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4] +1385,1673,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R] +1386,1674,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C +1387,1675,Imine_imine_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=NC([CH2,CH3])=NN([CH2,CH3])cc" +1388,1676,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2 +1389,1677,Imine_one_fives_C,cc[N!R]=C2C(=[!#1!#6])c5ccccc5N2 +1390,1678,Imine_one_fives_D,C1(=[!#1!#6])C(N=CS1)=O +1391,1679,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3 +1392,1680,Imine_naphthol_A,"c12c([cH][cH][cH][cH]1)c(c([cH][cH]2)C(=N-cc)[CH2,CH3])[OH1]" +1393,1681,Pyrrole_C,"[#7]1([CX4])-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6!H0]=,:[#6]1cc" +1394,1682,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]" +1395,1683,Pyrrole_E,"[#7]1(c2[cH]a[a!c]a2)-,:[#6]([CX4])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CX4]" +1396,1684,Pyrrole_F,[cH]1[cH]n(-c2[a!c]ccc2C#[NX1])c[cH]1 +1397,1685,Pyrrole_G,"n1(c2c[cH]c([$([NH2]),$(cn)])c[cH]2)[cH][cH][cH][cH]1" +1398,1686,Pyrrole_H,"C1=[Nv4,N+]([#6])CC[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]12" +1399,1687,Pyrrole_I,"[#7]1([CH2,CH3])-,:[#6]2=,:[#6](-,:[#6]:[#6]-,:[#6]2=[OX1])-,:[#6]=,:[#6]1[CH2,CH3]" +1400,1688,Pyrrole_J,"[#6]1(=,:[#6]2-,:[#6](=,:[#6](-,:[#7]1C(O)=[OX1])[CH2,CH3])S[CH2]S2)[CH2,CH3]" +1401,1689,Pyrrole_K,"[#6]1(-,:[#7!H0]-,:[#6](c2[cH][cH][cH][cH][cH]2)=,:[#6]([CH2,CH3])-,:[#6H]=,:1)C(=[OX1])[OH1]" +1402,1690,Pyrrole_L,"[n!H0]1c(C(=[OX1])O[CH2,CH3])c([CH2,CH3])c([CH2][CH2,CH3])c1[CH2][CH2,CH3]" +1403,1691,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]" +1404,1692,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]" +1405,1693,Pyrrole_O,"[#7]1([CH2,CH3])-,:[#6]([CH2,CH3])=,:[#6](C(=[OX1])[#6])-,:[#6]=,:[#6]1-cc" +1406,1694,Thiaz_ene_D,"c2ccccc2[#7][#6]1=,:[#7+,#7v4]-,:[#6](c3ccccc3)=,:[#6][#16]1" +1407,1695,Thiaz_ene_E,"C1(S[#6R])=C([C!H0]([#6])[#6])SC(N1([H,CH2,CH3]))=[OX1]" +1408,1696,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7" +1409,1697,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34 +1410,1698,Quinone_D,"[!#1!#6]=[#6]1[#6]=,:[#6][#6]=,:[#6][#6]1=[!#1!#6]" +1411,1699,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3 +1412,1700,Diazox_B,Clc2cc1nonc1cc2 +1413,1701,Diazox_C,N2=Nc1n[a!c]nc1N=Ncc2 +1414,1702,Diazox_D,[C!H0]1([OH1])c2n[a!c]nc2[C!H0]([OH1])C=C1 +1415,1703,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12 +1416,1704,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4 +1417,1705,Sulfonamide_C,[cH]1c([N!H0]S(=[OX1])(=[OX1])c2ccc([!#1!#6])cc2)[cH]c3c(O[CH2]O3)[cH]1 +1418,1706,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]) +1419,1707,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc +1420,1708,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc" +1421,1709,Sulfonamide_G,"[CH3]c5nc([N!H0]S(c2[cH][cH]c([cH][cH]2)O[CH2][CH2][CH2,CH3])(=[OX1])(=[OX1]))[cH][cH][cH]5" +1422,1710,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2 +1423,1711,Sulfonamide_I,"S(=[OX1])(=[OX1])(c1cn([CH2,CH3])cn1)[N!H0]c2cnn([CH2]ccO[CH2,CH3])c2" +1424,1712,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1" +1425,1713,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4] +1426,1714,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1 +1427,1715,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1 +1428,1716,Thiazole_amine_B,"c1(ccc([CH2,CH3])cc1)-c2nc([NH2])sc2[CH3]" +1429,1717,Thiazole_amine_C,"c1([N!H0][CH2]c2[cH][cH][cH]o2)nc(aaa([$(O[CH2,CH3]),CH2,CH3])aa)[cH]s1" +1430,1718,Thiazole_amine_D,"[#16]1-,:[#6]([N!H0]c2c([CH2,CH3,$(cc)])cccc2)=,:[#7+,#7v4]([CH2,CH3])-,:[#6]([#6])=,:[#6H]1" +1431,1719,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1 +1432,1720,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1 +1433,1721,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1" +1434,1722,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3" +1435,1723,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc" +1436,1724,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]" +1437,1725,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1 +1438,1726,Thiazole_amine_M,"c1([N!H0]cc[CH2,CH3])nc(c2ccncc2)[cH]s1" +1439,1727,Thiazole_amine_N,"[CH2,CH3]Oc1[cH][cH]c(O[CH2,CH3])[cH]c1[N!H0]c2scc(-c3ccc(O[CH2,CH3])cc3)n2" +1440,1728,Furan_acid_A,"c1(oc([CH2,CH3])c([CH2]Occ)[cH]1)[CX3](=[OX1])[OH1]" +1441,1729,Furan_A,"c1(oc([CH2,CH3])[cH][cH]1)[C!H0]([OH1])C#C[CX4]" +1442,1730,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC" +1443,1731,Colchicine_B,"[CH2,CH3]Sc1ccc(cc1)C2=CC(=[OX1])[#6]3=,:[#6]-,:[#8]-,:[#6]=,:[#6]3C([OH1])=C2" +1444,1732,Colchicine_het,"c1cccc3-,:[#7]([CH2,CH3])-,:[#6](=NN=[#6]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]2)-,:[#16]-,:c13" +1445,1733,Rhod_sat_B,"N1(c2c([CH2,CH3])cccc2)C(=S)N([CH2]aaaaa)[CH2]C1=[OX1]" +1446,1734,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1] +1447,1735,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1] +1448,1736,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1] +1449,1737,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S +1450,1738,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1] +1451,1739,Melamine_A,"o1[cH][cH][cH]c1[CH2][N!H0]c1c2ccccc2nc([N!H0]c4c([H,CH2,CH3,SX2,$(O[C!H0])])cc([H,CH2,CH3,SX2,$(O[C!H0])])c([H,CH2,CH3,SX2,$(O[C!H0])])c4)n1" +1452,1740,Melamine_B,"n1c(N([CH2,CH3])[CH2,CH3])nc(N([CH2,CH3])[CH2,CH3])nc1N([C!H0])C=[OX1]" +1453,1741,Imidazole_B,"[CH2,CH3][CH2]S[CH2][#6]1=,:[#6]-,:[#7!H0]-,:[#6]=,:[#7]1" +1454,1742,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14 +1455,1743,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12 +1456,1744,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1] +1457,1745,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4" +1458,1746,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4" +1459,1747,Naphth_ene_one_A,"c1cc3c4c(c1)cccc4C(=CC3=[OX1])O[CH2,CH3]" +1460,1748,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F) +1461,1749,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7] +1462,1750,Coumarin_A,"c1(O[C!H0])[cH][cH]c2c3[cH][cH]c(O[CH2,CH3])[cH]c3-,:[#6](=[OX1])-,:[#8]c2c1" +1463,1751,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12" +1464,1752,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1] +1465,1753,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1 +1466,1754,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23" +1467,1755,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2" +1468,1756,Coumarin_G,"c1c([F,Cl,Br,I])cc2c(c1[F,Cl,Br,I])OC(=[N!H0])C(C(=[OX1])[NH2])=[C!H0]2" +1469,1757,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12" +1470,1758,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1 +1471,1759,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1 +1472,1760,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1 +1473,1761,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1 +1474,1762,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1] +1475,1763,Tetrazole_A,"[CH2,CH3][#6]1=,:[#7]-,:[#7]=,:[#7]-,:[#7]1c2[cH][cH]c(O[CH3])[cH][cH]2" +1476,1764,Misc_aminal_acid,"c1ccc4c(c1)COC(N4C(=[OX1])[CH2,CH3])(C(=[OX1])[OH1])[CH2,CH3]" +1477,1765,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1 +1478,1766,Misc_anilide_A,"c1([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH][cH]c([CH2,CH3])c([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH]1" +1479,1767,Misc_anilide_B,"c1([N!H0]C(=[OX1])[N!H0][CH2][CH2][CH2,CH3])c([CH2,CH3])[cH]c(Br)[cH]c1[CH2,CH3]" +1480,1768,Misc_anisole_A,"c1(c([cH]c5c([cH]1)c([cH]c([cH]5)c3[cH][cH]c(c([cH]3)O[CH2,CH3])O[CH2,CH3])[N!H0][CH3])O[CH2,CH3])O[CH2,CH3]" +1481,1769,Misc_anisole_B,"c1([cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH][cH]1)C(=[OX1])[CH2]N([CH2,CH3])c2ccc([CH2,CH3])cc2" +1482,1770,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc +1483,1771,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc +1484,1772,Misc_furan_A,"c3c([CH2,CH3])c([CH2,CH3])oc3[CH2]N[CH2][C!H0](O[CH2,CH3])[CH2]Oc1ccc2c(O[CH2]O2)c1" +1485,1773,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]" +1486,1774,Misc_phthal_thio_N,"c1(c2ccccc2)nc(N([CH2,CH3])[CH2][CH2]NC(=[OX1])c3c(C(=[OX1])[OH1])cccc3)sn1" +1487,1775,Misc_pyridine_OC,"[OX1]=C(c1[cH]c(O[CH3])nc(O[CH3])[cH]1)[N!H0][C!H0]([CH2,CH3])[CH2,CH3]" +1488,1776,Misc_pyrrole_benz,"[#7]1(-c2[cH][cH][cH][cH]c2C(=[OX1])[N!H0][C!H0]([CH2,CH3])[CH2]O-cc)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1" +1489,1777,Misc_pyrrole_thiaz,"c1([C!H0]([CH2,CH3])[CH2][CH2]N[CH2]c2[n!H0]ccc2)nc(-c3ccccc3)[c!H0]s1" +1490,1778,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1 +1491,1779,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1] +1492,1780,Misc_urea_A,"c1(C([CX4])([CX4])[N!H0]C(=[OX1])N([CH2][CH2,CH3])[CH2][CH2][CH2][CH2]-cc)[cH][cH][cH]c(C(=[CH2])[CH2,CH3])[cH]1" +1493,1781,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2] +1494,1782,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1] +1495,1783,Pyrazole_amino_A,"[#6]1=,:[#6]([NH2])-,:[#7]-,:[#7]=,:[#6]1-[#6]2=,:[#6]([CH2,CH3])-,:[#8]-,:[#6!H0]=,:[#6!H0]2" +1496,1784,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6" +1497,1785,Indole_3yl_alk_B,"c12[cH][cH][cH][cH]c1-,:[#6]([CH2,CH3])=,:[#6](-cc)-,:[#7]2-!@cc" +1498,1786,Mannich_B,"c1c[cH]c2O[CH2]N(ccO[CH2,CH3])[CH2]c2[cH]1" +1499,1787,Mannich_catechol_A,"[cH]1c([#8])c([#8])[cH]c2c1O[CH2]N([CH2,CH3])[CH2]2" +1500,1788,Dyes7A,"c1ccccc1N([CH2,CH3])[C!H0]=[C!H0]C=!@[C!H0][C!H0]=CC=&@Nc2ccccc2" +1501,1789,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3" +1502,1790,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1" +1503,1791,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]) +1504,1793,Retinoic acid derivatives_1,"[$([OH1][CX3](=[OX1])c1[cH][cH]c(-c2c[cH]c3[cH]c([H,CX4])c([H,CX4])[cH]c3[cH]2)[cH][cH]1),$([OH1][CX3](=[OX1])c1[cH]c2[cH]cc(-c3[cH]c([H,CX4])c([H,CX4])[cH][cH]3)[cH]c2[cH][cH]1)]" +1505,1795,Thiazole_amine_I,"[CH2,CH3][N!H0]C=N[N!H0][#6]1=,:[#7]-,:[#6](-cc)=,:[#6!H0]-,:[#16]1" +1506,1796,Indol_3yl_alk,"[H,CH2,CH3][#7]1-,:[#6]([CH2,CH3,$([a!c](:[#6]-,:[#7])),$([C!H0][#7]),$([C!H0]([CH2,CH3])[N!H0][CH2,CH3]),$([C!H0]([CH2,CH3])[CH2][N!H0][CH2,CH3])])=,:[#6]([CX4!H0])-,:c2[cH]cccc12" +1507,1797,Tetrazole_hzide,"a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])[N!H0][N!H0][#6]2=,:[#7]-,:[#7]=,:[#7]-,:[#7]2[#6]" +1508,1798,Three-membered heterocycles (LS),[!#6!#1]1~*~*~1 +1509,1799,Three-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~1 +1510,1800,Saturated three-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-1 +1511,1801,Unsaturated three-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1~[#6]=[#6]~1),$([!#1!#6]1=[#6]~[#6]~1)]" +1512,1802,Three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[#6]~1 +1513,1803,Saturated three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[#6]-1 +1514,1804,Unsaturated three-membered heterocycles with two heteroatoms (LS),"[$([!#1!#6]1=[!#1!#6]~[#6]~1),$([!#1!#6]1~[!#6!#1]=[#6]~1)]" +1515,1805,Three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~1 +1516,1806,Saturated three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-1 +1517,1807,Unsaturated three-membered heterocycles with three heteroatoms (LS),[!#1!#6]1~[!#1!#6]=[!#1!#6]~1 +1518,1808,Three-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~1 +1519,1809,Three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6&R1]~[#6&R1]~1 +1520,1810,Saturated three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6&R1]-[#6&R1]-1 +1521,1811,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1 +1522,1812,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1 +1523,1813,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1 +1524,1814,Unsaturated three-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1~[#6R1]=[#6R1]~1),$([!#1!#6;R1]1=[#6R1]~[#6R1]~1)]" +1525,1815,Azirines (HS),"[$([#7R1]1-[#6R1]=[#6R1]-1),$([#7R1]1=[#6R1]-[#6R1]-1)]" +1526,1816,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1 +1527,1817,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1 +1528,1818,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1 +1529,1819,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1 +1530,1820,Three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~1 +1531,1821,Saturated three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-1 +1532,1822,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1 +1533,1823,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1 +1534,1824,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1 +1535,1825,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1 +1536,1826,Unsaturated three-membered heterocycles with two heteroatoms (HS),"[$([!#1!#6;R1]1=[!#1!#6;R1]~[#6R1]~1),$([!#1!#6;R1]1~[!#6!#1;R1]=[#6R1]~1)]" +1537,1827,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1 +1538,1828,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1 +1539,1829,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1 +1540,1830,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1 +1541,1831,Three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~1 +1542,1832,Saturated three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-1 +1543,1833,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1 +1544,1834,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1 +1545,1835,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1 +1546,1836,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1 +1547,1837,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1 +1548,1838,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1 +1549,1839,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1 +1550,1840,Unsaturated three-membered heterocycles with three heteroatoms (HS),[!#1!#6;R1]1-[!#6!#1;R1]=[!#6!#1;R1]1 +1551,1841,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1 +1552,1842,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1 +1553,1843,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1 +1554,1844,Four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~1)]" +1555,1845,Saturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1-[!#6!#1]-[#6]-[#6]-1),$([!#6!#1]1-[#6]-[!#6!#1]-[#6]-1)]" +1556,1846,Unsaturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]=[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]=[#6]~1),$([!#6!#1]1=[#6]~[!#6!#1]~[#6]~1)]" +1557,1847,Four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~1 +1558,1848,Saturated four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[#6]-1 +1559,1849,Unsaturated four-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]=[#6]~1)]" +1560,1850,Four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~1 +1561,1851,Saturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-1 +1562,1852,Unsaturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~1 +1563,1853,Four-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~1 +1564,1854,Four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~1 +1565,1855,Saturated four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6R1]-[#6R1]-[#6R1]-1 +1566,1856,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1 +1567,1857,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1 +1568,1858,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1 +1569,1859,Unsaturated four-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]=[#6R1]~[#6R1]~1)]" +1570,1860,Azetines (HS),"[$([#7R1]1=[#6R1]-[#6R1]-[#6R1]-1),$([#7R1]1-[#6R1]=[#6R1]-[#6R1]-1)]" +1571,1861,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1 +1572,1862,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1 +1573,1863,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1 +1574,1864,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1 +1575,1865,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1 +1576,1866,Four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]" +1577,1867,Saturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-[#6R1]-1),$([!#6!#1;R1]1-[#6R1]-[!#6!#1;R1]-[#6R1]-1)]" +1578,1868,Diazetidines (HS),"[$([NR1]1[CR1][CR1][NR1]1),$([NR1]1[CR1][NR1][CR1]1)]" +1579,1869,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1 +1580,1870,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1 +1581,1871,Dioxetanes (HS),"[$([OR1]1[OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]1)]" +1582,1872,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1 +1583,1873,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1 +1584,1874,Dithietanes (HS),"[$([SX2R1]1[SX2R1][CR1][CR1]1),$([SX2R1]1[CR1][SX2R1][CR1]1)]" +1585,1875,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1 +1586,1876,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1 +1587,1877,Unsaturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]=[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]=[#6R1]~1),$([!#6!#1;R1]1=[#6R1]~[!#6!#1;R1]~[#6R1]~1)]" +1588,1878,Diazetines (HS),"[$([#7]1=,:[#7]-,:[#6]-,=,:[#6]-,:1),$([#7]1-,:[#7]=,:[#6]-,:[#6]-,=,:1),$([#7]1-,:[#7]-,:[#6]=,:[#6]-,=,:1),$([#7]1=,:[#6]-,:[#7]-,=,:[#6]-,:1)]" +1589,1879,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1" +1590,1880,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1" +1591,1881,Four-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~1 +1592,1882,Saturated four-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-[#6]-1 +1593,1883,Unsaturated four-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]=[#6]~[#6]~1)]" +1594,1884,Diazirenes (HS),"[$([#7R1]1-[#7R1]=[#6R1]-1),$([#7R1]1=[#7R1]-[#6R1]-1)]" +1595,1886,Four-membered heterocycles (LS),[!#6!#1]1~*~*~*~1 +1596,1887,Five-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~1 +1597,1888,Five-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~1 +1598,1889,Saturated five-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCC1 +1599,1890,Unsaturated five-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=CCCC1),$([!#6!#1]1C=CCC1),$([!#6!#1]1CC=CC1),$([!#6!#1]1=CC=CC1);!$(n1cccc1)]" +1600,1891,Aromatic five-membered heterocycles with one heteroatom (LS),[a!#6]1cccc1 +1601,1892,Five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~1)]" +1602,1893,Saturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCC1),$([!#6!#1]1C[!#6!#1]CC1)]" +1603,1894,Unsaturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]C-,=CC1),$([!#6!#1]1[!#6!#1]=CCC1),$([!#6!#1]1[!#6!#1]C=CC1),$([!#6!#1]1=C[!#6!#1]-,=CC1),$([!#6!#1]1C[!#6!#1]CC=1),$([!#6!#1]1C[!#6!#1]C=C1)]" +1604,1895,Aromatic five-membered heterocycles with two heteroatoms (LS),"[$([a!#6]1[a!#6]ccc1),$([a!#6]1c[a!#6]cc1)]" +1605,1896,Five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]" +1606,1897,Saturated five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]C1)]" +1607,1899,Aromatic five-membered heterocycles with three heteroatoms (LS),"[$([a!#6]1[a!#6][a!#6]cc1),$([a!#6]1[a!#6]c[a!#6]c1)]" +1608,1900,Five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1 +1609,1901,Saturated five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]C1 +1610,1902,Unsaturated five-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1][!#6!#1]-,=[!#6!#1][#6]1),$([!#6!#1]1[!#6!#1]=[!#6!#1][!#6!#1][#6]1),$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1][#6]=1)]" +1611,1903,Aromatic five-membered heterocycles with four heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6]c1 +1612,1904,Five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1 +1613,1905,Saturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1 +1614,1906,Unsaturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1=[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1 +1615,1907,Aromatic five-membered heterocycles with five heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6][a!#6]1 +1616,1908,Five-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~1 +1617,1909,Five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1 +1618,1910,Saturated five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1]1 +1619,1911,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1 +1620,1912,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1 +1621,1913,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1 +1622,1914,Unsaturated five-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1]=[CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1]=[CR1][CR1]1),$([!#6!#1;R1]1=[CR1][CR1]=[CR1][CR1]1);!$(n1cccc1)]" +1623,1915,Pyrrolines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1]1)]" +1624,1916,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1 +1625,1917,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1 +1626,1918,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1 +1627,1919,Dihydrofurans (HS),"[$([OR1]1[CR1]=[CR1][CR1][CR1]1),$([OR1]1[CR1][CR1]=[CR1][CR1]1)]" +1628,1920,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1 +1629,1921,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1 +1630,1922,Dihydrothiophenes (HS),"[$([SR1]1[CR1]=[CR1][CR1][CR1]1),$([SR1]1[CR1][CR1]=[CR1][CR1]1)]" +1631,1923,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1 +1632,1924,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1 +1633,1925,Aromatic five-membered heterocycles with one heteroatom (HS),[a!#6;R1]1[cR1][cR1][cR1][cR1]1 +1634,1926,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1 +1635,1927,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1 +1636,1928,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1 +1637,1929,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12 +1638,1930,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12 +1639,1931,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12 +1640,1932,Five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1)]" +1641,1933,Saturated five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1]1)]" +1642,1934,Diazolidines (HS),"[$([NR1]1[NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1]1)]" +1643,1935,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1 +1644,1936,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1 +1645,1937,Dioxolanes (HS),"[$([OR1]1[OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1]1)]" +1646,1938,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1 +1647,1939,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1 +1648,1940,Dithiolanes (HS),"[$([SR1]1[SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1]1)]" +1649,1941,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1 +1650,1942,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1 +1651,1944,Pyrazolines (HS),"[$([NR1]1=[NR1][CR1][CR1][CR1]1),$([NR1]1[NR1]=[CR1][CR1][CR1]1),$([NR1]1[NR1][CR1]=[CR1][CR1]1)]" +1652,1945,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1 +1653,1946,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1 +1654,1947,Imidazolines (HS),"[$([NR1]1=[CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1]=[CR1][CR1]1),$([NR1]1[CR1][NR1][CR1]=[CR1]1)]" +1655,1948,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1 +1656,1949,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1 +1657,1950,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1 +1658,1951,Dioxolenes (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]=[CR1]1)]" +1659,1952,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1 +1660,1953,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1 +1661,1954,Dithiolenes (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]1),$([SR1]1[CR1][SR1][CR1]=[CR1]1)]" +1662,1955,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1 +1663,1956,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1 +1664,1957,Aromatic five-membered heterocycles with two heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][cR1][cR1][cR1]1),$([a!#6;R1]1[cR1][a!#6;R1][cR1][cR1]1)]" +1665,1958,Diazoles (HS),"[$([nR1]1[nR1][cR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][cR1]1)]" +1666,1959,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1 +1667,1960,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1 +1668,1961,Oxazoles (HS),"[$([oR1]1[nR1][cR1][cR1][cR1]1),$([oR1]1[cR1][nR1][cR1][cR1]1)]" +1669,1962,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1 +1670,1963,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1 +1671,1964,Thiazoles (HS),"[$([sR1]1[nR1][cR1][cR1][cR1]1),$([sR1]1[cR1][nR1][cR1][cR1]1)]" +1672,1965,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1 +1673,1966,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1 +1674,1967,Five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]" +1675,1968,Saturated five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]" +1676,1969,Triazolidines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1]1)]" +1677,1970,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1 +1678,1971,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1 +1679,1972,Trioxolanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1]1)]" +1680,1973,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1 +1681,1974,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1 +1682,1975,Trithiolanes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1]1)]" +1683,1976,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1 +1684,1977,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1 +1685,1979,"1,2,3-Triazolines (HS)","[$([NR1]1=[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][NR1][CR1][CR1]=1),$([NR1]1[NR1][NR1][CR1]=[CR1]1)]" +1686,1980,"1,2,4-Triazolines (HS)","[$([NR1]1=[NR1][CR1][NR1][CR1]1),$([NR1]1[NR1]=[CR1][NR1][CR1]1),$([NR1]1[NR1][CR1]=[NR1][CR1]1)]" +1687,1981,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1 +1688,1982,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1 +1689,1983,Aromatic five-membered heterocycles with three heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][a!#6;R1][cR1][cR1]1),$([a!#6;R1]1[a!#6;R1][cR1][a!#6;R1][cR1]1)]" +1690,1984,Triazoles (HS),"[$([nR1]1[nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1]1)]" +1691,1985,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1 +1692,1986,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1 +1693,1987,Oxadiazoles (HS),"[$([oR1]1[nR1][nR1][cR1][cR1]1),$([oR1]1[nR1][cR1][nR1][cR1]1),$([oR1]1[nR1][cR1][cR1][nR1]1),$([oR1]1[cR1][nR1][nR1][cR1]1)]" +1694,1988,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1 +1695,1989,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1 +1696,1990,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1 +1697,1991,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1 +1698,1992,Five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1 +1699,1993,Saturated five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1][CR1]1 +1700,1994,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1 +1701,1995,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1 +1702,1996,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1 +1703,1997,Unsaturated five-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1][!#6!#1;R1]-,=[!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1]=[!#6!#1;R1][!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][#6R1]=1)]" +1704,1998,Aromatic five-membered heterocycles with four heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][cR1]1 +1705,1999,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1 +1706,2000,Oxatriazoles (HS),"[$([oR1]1[nR1][nR1][nR1][cR1]1),$([oR1]1[nR1][nR1][cR1][nR1]1)]" +1707,2001,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1 +1708,2002,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1 +1709,2003,Thiatriazoles (HS),"[$([sR1]1[nR1][nR1][nR1][cR1]1),$([sR1]1[nR1][nR1][cR1][nR1]1)]" +1710,2004,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1 +1711,2005,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1 +1712,2006,Five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1 +1713,2007,Saturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1 +1714,2008,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1 +1715,2009,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1 +1716,2010,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1 +1717,2011,Unsaturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1=[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1 +1718,2012,Aromatic five-membered heterocycles with five heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][a!#6;R1]1 +1719,2013,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1 +1720,2014,Six-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~*~1 +1721,2015,Six-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~[#6]~1 +1722,2016,Saturated six-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCCC1 +1723,2017,Unsaturated six-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1=C~C~C~C~C~1),$([!#1!#6]1~C=C~C~C~C~1),$([!#1!#6]1~C~C=C~C~C~1);!$([a!c]1ccccc1)]" +1724,2018,Aromatic six-membered heterocycles with one heteroatom (LS),[a!c]1ccccc1 +1725,2019,Six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[#6]~[!#6!#1]~[#6]~[#6]~1)]" +1726,2020,Saturated six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCCC1),$([!#6!#1]1C[!#6!#1]CCC1),$([!#6!#1]1CC[!#6!#1]CC1)]" +1727,2022,Aromatic six-membered heterocycles with two heteroatoms (LS),"[$([a!c]1[a!c]cccc1),$([a!c]1c[a!c]ccc1),$([a!c]1cc[a!c]cc1)]" +1728,2023,Six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]" +1729,2024,Saturated six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CCC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]CC1),$([!#6!#1]1C[!#6!#1]C[!#6!#1]C1)]" +1730,2026,Aromatic six-membered heterocycles with three heteroatoms (LS),"[$([a!c]1[a!c][a!c]ccc1),$([a!c]1[a!c]c[a!c]cc1),$([a!c]1c[a!c]c[a!c]c1)]" +1731,2027,Six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[!#6!#1]~[#6]~1)]" +1732,2028,Saturated six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1][!#6!#1]C[!#6!#1]C1),$([!#6!#1]1[!#6!#1]C[!#6!#1][!#6!#1]C1)]" +1733,2030,Aromatic six-membered heterocycles with four heteroatoms (LS),"[$([a!c]1[a!c][a!c][a!c]cc1),$([a!c]1[a!c][a!c]c[a!c]c1),$([a!c]1[a!c]c[a!c][a!c]c1)]" +1734,2031,Six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1 +1735,2032,Saturated six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-C-1 +1736,2034,Aromatic six-membered heterocycles with five heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c]c1 +1737,2035,Saturated six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1 +1738,2036,Unsaturated six-membered heterocycles with six heteroatoms (LS),[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)] +1739,2037,Aromatic six-membered heterocycles with six heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c][a!c]1 +1740,2038,Six-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~[*R1]~1 +1741,2039,Six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1 +1742,2040,Saturated six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1][CR1]1 +1743,2041,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1 +1744,2042,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1 +1745,2043,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1 +1746,2044,Unsaturated six-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1=[CR1]~[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]=[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]~[CR1]=[CR1]~[CR1]~[CR1]~1);!$([a!c]1ccccc1)]" +1747,2045,Tetrahydropyridines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1][CR1]1)]" +1748,2046,Dihydropyridines (HS),"[$([NR1]1=[CR1][CR1]-,=[CR1]-,=[CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]-,=[CR1]-,=1),$([NR1]1[CR1]=[CR1][CR1]=[CR1][CR1]1)]" +1749,2047,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1" +1750,2048,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1" +1751,2049,Aromatic six-membered heterocycles with one heteroatom (HS),[a!c;R1]1[cR1][cR1][cR1][cR1][cR1]1 +1752,2050,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1 +1753,2051,Six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~1)]" +1754,2052,Saturated six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1][!#6!#1;R1][CR1][CR1]1)]" +1755,2053,Hexahydrodiazines,"[$([NR1]1[NR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1][NR1][CR1][CR1]1)]" +1756,2054,Dioxanes,"[$([OR1]1[OR1][CR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][CR1][OR1][CR1][CR1]1)]" +1757,2055,Dithianes,"[$([SR1]1[SR1][CR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][CR1][SR1][CR1][CR1]1)]" +1758,2060,Dioxines (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]=[CR1]1),$([OR1]1[CR1]=[CR1][OR1][CR1]=[CR1]1)]" +1759,2061,Aromatic six-membered heterocycles with two heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][cR1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][cR1][a!c;R1][cR1][cR1]1)]" +1760,2062,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1 +1761,2063,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1 +1762,2064,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1 +1763,2065,Six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]" +1764,2066,Saturated six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]" +1765,2067,Hexahydrotriazines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][NR1][CR1]1)]" +1766,2068,Trioxanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][OR1][CR1]1)]" +1767,2069,Trithianes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][SR1][CR1]1)]" +1768,2071,Aromatic six-membered heterocycles with three heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][a!c;R1][cR1]1)]" +1769,2072,Triazines (HS),"[$([nR1]1[nR1][nR1][cR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][nR1][cR1]1)]" +1770,2074,Saturated six-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][!#6!#1;R1][CR1]1)]" +1771,2075,Hexahydrotetrazines (HS),"[$([NR1]1[NR1][NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][NR1][CR1]1),$([NR1]1[NR1][NR1][CR1][NR1][CR1]1)]" +1772,2076,Tetroxanes (HS),"[$([OR1]1[OR1][OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][OR1][CR1]1)]" +1773,2077,Tetrathianes (HS),"[$([SR1]1[SR1][SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][SR1][CR1]1)]" +1774,2080,Aromatic six-membered heterocycles with four heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][a!c;R1][cR1][a!c;R1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][a!c;R1][cR1]1)]" +1775,2081,Tetrazines (HS),"[$([nR1]1[nR1][nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][nR1][cR1][nR1][cR1]1),$([nR1]1[nR1][cR1][nR1][nR1][cR1]1)]" +1776,2082,Six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1 +1777,2083,Saturated six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[CR1]-1 +1778,2085,Aromatic six-membered heterocycles with five heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][cR1]1 +1779,2086,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1 +1780,2087,Six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1 +1781,2088,Saturated six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1 +1782,2089,Unsaturated six-membered heterocycles with six heteroatoms (HS),[$([!#6!#1;R1]1=[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)] +1783,2090,Aromatic six-membered heterocycles with six heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][a!c;R1]1 +1784,2091,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1 +1785,2092,Six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1 +1786,2093,Dithiines (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]=[CR1]1),$([SR1]1[CR1]=[CR1][SR1][CR1]=[CR1]1)]" +1787,2095,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1 +1788,2096,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1 +1789,2097,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1 +1790,2100,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3] +1791,2101,Allyl halides,"[CX3]=[CX3][CX4][F,Cl,Br,I]" +1792,2102,Allyl fluorides,[CX3]=[CX3][CX4]F +1793,2103,Allyl chlorides,[CX3]=[CX3][CX4]Cl +1794,2104,Allyl bromides,[CX3]=[CX3][CX4]Br +1795,2105,Allyl iodides,[CX3]=[CX3][CX4]I +1796,2106,Vinyl fluorides,F[CX3]=[CX3] +1797,2107,Vinyl chlorides,Cl[CX3]=[CX3] +1798,2108,Vinyl bromides,Br[CX3]=[CX3] +1799,2109,Vinyl iodides,I[CX3]=[CX3] +1800,2110,Alkynyl fluorides,F[CX2]#[CX2] +1801,2111,Alkynyl chlorides,Cl[CX2]#[CX2] +1802,2112,Alkynyl iodides,I[CX2]#[CX2] +1803,2113,Alkynyl bromides,Br[CX2]#[CX2] +1804,2114,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]" +1805,2115,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c" +1806,2116,Diarylthioethers,c[SX2&!$([SX2r3])]c +1807,2117,"1,2 – Diphenols",c([OH1])c([OH1]) +1808,2118,"1,3 – Diphenols",c([OH1])[aR1]c([OH1]) +1809,2119,"1,4 - Diphenols",c1([OH1])aac([OH1])aa1 +1810,2120,"1,2 – Dithiophenols",c([SH1])c([SH1]) +1811,2121,"1,3 – Dithiophenols",c([SH1])[aR1]c([SH1]) +1812,2122,"1,4 – Dithiophenols",c1([SH1])aac([SH1])aa1 +1813,2123,"1,2 – Aminophenols","c([OH1])c[NX3]([#1,#6])[#1,#6]" +1814,2124,"1,3 – Aminophenols","c([OH1])[aR1]c[NX3]([#1,#6])[#1,#6]" +1815,2125,"1,4 – Aminophenols","c1([OH1])aac([NX3]([#1,#6])[#1,#6])aa1" +1816,2126,"1,2 – Aminothiophenols","c([SH1])c[NX3]([#1,#6])[#1,#6]" +1817,2127,"1,3 – Aminothiophenols","c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]" +1818,2128,"1,4 – Aminothiophenols","c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1" +1819,2129,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]" +1820,2130,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]" +1821,2131,Carbonic acid esters,"[#1,#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]" +1822,2133,Phosphonic acid amides,[OX1]=[Pv5X4]([NX3])([#6])[!#6!$([SX2])] +1823,2136,Aldehyde,[CX3H1](=O)[#6] +1824,2138,AliphaticEther,[!$(C=O);$([C&!a])][OX2&H0][!$(C=O);$([C&!a])] +1825,2141,AminoAcids,"[$([NX3,NX4+][CX4H]([*])[CX3](=[OX1])[O,N]),$([$([$([NX3H2,NX4H3+]),$([NX3H](C)(C))][CX4H2][CX3](=[OX1])[OX2H,OX1-,N])])]" +1826,2142,AromaticHalogen,"[$([a][F,Cl,I])]" +1827,2143,AromaticNGroups,"[$([a]N(~O)~O),$([a]N([#1])[*]),$([a]N([#1])[!#1])]" +1828,2144,AromaticSulphonicAcid,"[$([#16X4](=[OX1])(=[OX1])([a])[OX2H,OX1H0-]),$([#16X4+2]([OX1-])([OX1-])([a])[OX2H,OX1H0-])]" +1829,2145,AzoGroup,[$([!R&N]=[!R&N])] +1830,2146,CyanoGroupOnMoreThanEightAtomsChain,[N]#[C]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0] +1831,2147,Epoxide,[$(C1OC1)] +1832,2148,Esters,[#6][CX3](=O)[$([OX2H0]([#6])[#6])] +1833,2149,Formaldehyde,[CX3H2](=O) +1834,2151,Ketone,[C][C](=O)[C] +1835,2152,MoreThanTwoHydroxyOnAromaticRing,"[$([a&R]([OX2H])[a&R]([OX2H])),$([a&R]([OX2H])a[a&R]([OX2H])),$([a&R]([OX2H])aa[a&R]([OX2H]))]" +1836,2153,Nitrile,[C]#[N] +1837,2154,NNitroso,[$(NN=O)] +1838,2157,PyridineRing,[$(n1ccccc1)] +1839,2159,TerminalTertButyl,[$([C]([CH3])([CH3])([CH3])([*]))] +1840,2160,TertiaryAmine,[!R&NX3&H0] +1841,2161,TriazineRing,"[$(n1nnccc1),$(n1ncncc1),$(n1cncnc1)]" +1842,2162,Trifluoromethyl,[$([*]C(F)(F)F)] +1843,2166,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3 +1844,2167,Phenoxazines,"[OX1,N]=[#6]1-,:[#6]=,:[#6]2-,:[#16X2,#8X2]-,:[#6]3=,:[#6]-,:[#6](=,:[#6]-,:[#6]=,:[#6]3-,:[#7]=,:[#6]2-,:[#6]=,:[#6]1)" +1845,2168,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O" +1846,2169,Imidazotriazoles,"[c,n]1cnn2c([NH])cnc12" +1847,2170,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1" +1848,2171,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1 +1849,2172,NCCN,"[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]-[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]" +1850,2173,Picolylamines_A,"[$([NX3][CH2]c1ncnc([NX3])c1),$([NX3][CH2]c1nccc([NX3])n1)]" +1851,2174,Picolylamines_B,"[$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]n([H,CH3])cc1),$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]ccn1[H,CH3])]" +1852,2175,Picolylamines_C,"c1cccnc1[CH2!R][NX3!R]([H,CH3])[CH2!R]" +1853,2176,Bis-picolylamines,"[nv3X2]c([c,s,n])[CX4][NX3]([H,C])[CX4]c([c,s,n])[nv3X2,nv3X3H1]" +1854,2178,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2] +1855,2179,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1 +1856,2180,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c) +1857,2181,Diarylmethanes,"[$(c1[nX2][c,n][c,n][c,n]1),$([cr6][nX2r6])][CX4H2!R][$(c2[nX2][c,n][c,n][c,n]2),$([cr6][nX2r6])]" +1858,2183,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23" +1859,2184,Heterylamides_A,"[$([cr5][n,s;r5][n,o;r5]),$([cr5]([nr5])[s,o,n;r5])][Nv3X3H1!R][CX3!R](=[OX1])[$([cr5][nv3X2r5]),$(c1ncccc1),$(c1c([OX2][CH3])cccc1)]" +1860,2185,Heterylamides_B,"[$(c1nnc[o,n]1),$(c1nccs1)][Nv3X3H!R][C!R](=[OX1])[CX4!H0]([H,CX4])[SX2,n]cc" +1861,2186,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]) +1862,2187,8-Quinolinols,"[H,C][OX2]c1c([CX4][NX3])ccc2cccnc21" +1863,2188,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12 +1864,2189,Perchloroquinone,"[OX1]=[CX3]1C([F,Cl,Br,I])=C([F,Cl,Br,I])[CX3](=[OX1])C([F,Cl,Br,I])=C1[F,Cl,Br,I]" +1865,2190,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2] +1866,2191,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1 +1867,2192,A3,"[OH][CX3](=[OX1])[#6]1-,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:1" +1868,2193,B1,c1cccc2c1ccc([OH])n2 +1869,2194,B5,"[#6]1=,:[#6]-,:[#6]=,:[#6]([OH])-,:[#6]2=,:[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]2" +1870,2195,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2 +1871,2196,B10,c1ccc([SH])c2c1cccn2 +1872,2197,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2 +1873,2199,C2,[NH2]c1nc([NH2])cc([OH])n1 +1874,2200,"C3, C7, C8",[SH]c1nc([OH])ccn1 +1875,2201,C4,[OH]c1nc([SH])ccn1 +1876,2202,C5,[SH]c1nc([CH3])cc([CH3])n1 +1877,2203,C5*,[SH]c1nc([CX4])cc([CX4])n1 +1878,2204,"C6, C12",[OH]c1nc([OH])cc([CH3])n1 +1879,2205,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1 +1880,2206,C9,[NH2]c1ncnc2c1nc[nH]2 +1881,2207,C9*,[NH2]c1ncnc2c1nc[nX3]2 +1882,2208,"C10, C11","[CH3]c1nc([OH])cc([OH,CH3])n1" +1883,2209,"C10*, C11*","[CX4]c1nc([OH])cc([OH,CX4])n1" +1884,2210,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1" +1885,2211,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1" +1886,2212,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1" +1887,2213,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1" +1888,2214,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1" +1889,2215,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1" +1890,2216,"E6, E8","O=[#6]1-,:[#7]([H,CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])" +1891,2217,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])" +1892,2218,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1" +1893,2219,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])" +1894,2220,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])" +1895,2221,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH] +1896,2222,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2] +1897,2223,G1,[CX4][CX3](=[OX1])[NX3H1][OH] +1898,2224,G1*,[CX4][CX3](=[OX1])[NX3][OH] +1899,2225,G2,[nX3H]1cccc1C(=[OX1])[OH] +1900,2226,G2*,[nX3]1cccc1C(=[OX1])[OH] +1901,2227,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2 +1902,2228,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2 +1903,2229,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1 +1904,2230,G4*,C1C[NX3]CC[NX3]CC[NX3]1 +1905,2231,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]" +1906,2232,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH] +1907,2233,G7,c1cc2c(nc1)c3c(cccn3)cc2 +1908,2234,G8,c1ccc(c(c1)[OH])[OH] +1909,2235,"G9,G10","c1ccc(c(c1)[OH,SH])[OX2][CX4]" +1910,2236,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]" +1911,2237,H1,c1ccc2c(c1)ccc(c2[OH])[OH] +1912,2238,H2,c1ccc2cc(c(cc2c1)[OH])[OH] +1913,2239,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH] +1914,2240,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH] +1915,2241,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH] +1916,2242,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH] +1917,2243,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2] +1918,2244,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2] +1919,2245,H8 - H12,"C[CX3](=[OX1])[CX4!H0]([H,CX4,Cl])[CX3](=[OX1])C" +1920,2246,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C +1921,2249,Salts_C,"[!#1!#2!#5!#6!#7!#8!#9!#10!#14!#15!#16!#17!#18!#32!#33!#34!#35!#36!#51!#52!#53!#54!#84!#85!#86]~[#6,#7,#8,#16]" +1922,2254,Pt,[Pt] +1923,2258,N-methylol derivatives,[OX2;H1][CH2][NX3] +1924,2261,β-lactones and γ- sultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]" +1925,2265,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3] +1926,2271,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C" +1927,2273,Heterocyclic Polycyclic Aromatic Hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]" +1928,2274,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1 +1929,2275,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])" +1930,2276,Azafluorenones,"[OX1,SX1]=[#6X3]1c2c([nX2][cX3,nX2,nX3][cX3,nX2,nX3][cX3,nX2,nX3]2)[c,n]2c1[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])]2" +1931,2277,Cyanothioazinones,"[SX1]=[#6X3]1-,:[#7X3H1]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#7X2,#6X3!$([#6X3]=[A])]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#6X3]1([CX2]#[NX1])" +1932,2278,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12" +1933,2279,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0] +1934,2280,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12" +1935,2281,Benzoxathiolones,"[$([#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]),$([#8]1-,:[#6](-,:[#16]c4ccc(cc14)[#7,#8])=[OX1,SX1])]" +1936,2282,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]" +1937,2284,Pyrazolones,"[#7X2]1=,:[#6X3]-,:[#6X3](-,:[#6X3](-,:[#7X3]1)=[SX1,OX1])=,:[#6X3H1](-,:[#7X3H1])" +1938,2287,Thiopyrylium,c1[#16+]cccc1 +1939,2288,Pyrimidinones_A,"[OX1,SX1]=[#6X3]1[#7X3](-,:[#7X2]=,:[#6X3][NX3H1][#6])-,:[cX3!$([#6X3]=[A])]=,:[#7X2]-,:[cX3!$([#6X3]=[A])]=,:[cX3!$([#6X3]=[A])]1" +1940,2289,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]" +1941,2290,Pyrimidinones_C,"[OX1,SX1]=[#6X3]1[#7X3]-,:[#6X3!$([#6X3]=[A])](-[NX3])=,:[#7X2]-,:[#6X3]2([nX2][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])]c12)" +1942,2291,Pyrimidinodiones,"[#6X3]1(=[OX1,SX1])-,:[#7X3H1]-,:[#6X3](=[OX1,SX1])-,:[#7X3,#7X2]~[#6X3]([#7X2,#7X3;R1])-,:[#6X3]1[sX2r5R1,nX2r5R1,$([nx2r6R1]([cX3])[cX3])]" +1943,2292,Thienopyrimidinone_A,"[OX1,SX1]=[#6X3]1-,:[#7X3H1]-,:[#6X4]-,:[#7X3H1]-,:[#6]2-,:[#16X2,#8X2]-,:[#6]3[CX4][NX3,CX4][CX4][CX4]-,:[#6]3-,:[#6]12" +1944,2294,Piperazinediones,"[#7X3]1-,:[#6X3](=[OX1,SX1])-,:[#6X3](=[OX1,SX1])-,:[NX3]-,:[#6X3]2[cX3!$([#6X3]=[A])][cX3]([NX3H1][CX3]=[OX1])[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3]12" +1945,2295,4-Heteryl-thiazoles,"s1[c,nX2][c,nX2](-c(c)[nX2,nX3,sX2])[nX2]c1" +1946,2296,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0] +1947,2297,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1" +1948,2299,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2] +1949,2300,Cyanothioethers,"[NX1]#[CX2][CX4H2][SX2]c1n[c,n][c,n][c,n]n1" +1950,2301,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2 +1951,2302,Fused azacycles_A,"[nX2R1][c,n;R2]1[c,n;R2]([c,n;R1])[c,n][c,n][c,n;R2]([c,n;R1])[nR2]1[nX2R1]" +1952,2303,Fused azacycles_B,"[NX1]#[CX2]c1[c!$([#6]=[OX1])]n[n,c!$([#6]=[OX1])]2[c,n][c!$([#6]=[OX1])][c!$([#6]=[OX1])]nc12" +1953,2304,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21 +1954,2306,Arylethanolamines,"[$([NX3]([CX4,H])([CX4,H])[CX4]),$([OX2]([H,CX4])[CX4])][CX4!H0][CX4H2][NX3H1]c[nX2r6R1][nX2,nX3][nX2,cX3;R1][cX3,nX2][cX3,nX2][sX2,cX3][cX3]" +1955,2307,Azaspironones,"[X4;R2]12(-,:;@[#6X3]-,:;@[#6X3]-,:;@[#7X3]-,:;@[#6X3]-,:;@1)-,:;@[#16X2]-,:;@[#6X3]=,:;@[#7X2]-,:;@[#7X3]-,:;@2" +1956,2308,Radical,[#16;X3v3+0] +1957,2309,N⋯X halogen bonding,"N[F,Cl,Br,I]" +1958,2310,Charged atoms,"[+,-]" +1959,2311,Benzyl Imidazole scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*-,=*c:3:c:c:c:c:c:3" +1960,2312,6-Phenyl Napthaline type scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s][c,n,o,s]2)*~*c:3:c:c:c:c:c:3" +1961,2313,2-(2-(1H-pyrrol-2-yl)ethyl)-1H-benzoimidazole scaffold,"[c,n]:1:c:c2:c(:[c,n]:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*~*c3ccc*3" +1962,2315,2 - Olefin group,"[$([CX3H2]=[CX3H1]),$([CX3H1]=[CX3H1]),$([CX3H2]=[CX3H0]),$([CX3H1]=[CX3H0]),$([CX3H0]=[CX3H0])]" +1963,2318,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])] +1964,2319,6 - Methanol,[CX4H3][OX2H1] +1965,2320,7 - Water,[OX2H2] +1966,2322,9 - Сarbonyl,"[$([CX4H3][CX3](=[OX1])[#6]),$([CX4H2][CX3H0](=[OX1])[#6])]" +1967,2323,10 - Aldehyde,[CX3H1]([#6])=[OX1] +1968,2324,11 - Acetate group,"[$([CX4H3][CX3](=[OX1])[OX2][#6]),$([CX4H2][CX3](=[OX1])[OX2][#6])]" +1969,2325,12 - Formate group,[CX3H1](=[OX1])[OX2][#6] +1970,2327,14 - Primary amine,"[$([CX4H3][NX3H2]),$([CX4H2][NX3H2]),$([CX4H1][NX3H2])]" +1971,2329,16 - Tertiary amine,"[$([CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]),$([CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6])]" +1972,2332,19 - CCN,"[$([CX4H3][CX2]#[NX1]),$([CX4H2][CX2]#[NX1])]" +1973,2333,20 - COOH,"[$([CX3H0](=[OX1])[OX2H1]),$([CX3H1](=[OX1])[OX2H1])]" +1974,2334,21 - CCl,"[$([CX4H2!$([CX4H2](Cl)Cl)]Cl),$([CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl]),$([CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl])]" +1975,2335,22 - CCl2,"[$([CX4H2]([Cl])[Cl]),$([CX4H1]([!Cl!F])([Cl])[Cl]),$([CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F])]" +1976,2336,23 - CCl3,"[$([CX4H1]([Cl])([Cl])[Cl]),$([CX4H0]([!Cl!F])([Cl])([Cl])[Cl])]" +1977,2337,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl] +1978,2339,26 - CNO2,"[$([CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)])]" +1979,2341,28 - Carbon disulphide,[SX1]=[CX2]=[SX1] +1980,2342,29 - CH3SH,"[$([CX4H3][SX2H1]),$([CX4H2][SX2H1])]" +1981,2343,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1" +1982,2344,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1] +1983,2345,32 - Iodo compounds,[I] +1984,2346,33 - Bromo compounds,[Br!$([Br][cR])] +1985,2347,34 - Carbon triple bond,"[$([CX2H1]#[CX2H0]),$([CX2H0]#[CX2H0])]" +1986,2348,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3] +1987,2349,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1] +1988,2350,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3] +1989,2352,39 - DMF,"[$([CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3]),$([CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2])]" +1990,2353,40 - CF2,"[$([CX4](F)(F)(F)[!Cl!F]),$([CX4](F)(F)([!F!Cl!H])([!F!Cl!H])),$([CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]))]" +1991,2354,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6] +1992,2355,42 - SiH2,"[$([SiX4H3]),$([SiX4H2]([!$([OX2])])([!$([OX2])])),$([SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])])),$([SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]))]" +1993,2356,43 - SiO,"[$([SiX4H2][OX2]),$([SiX4H1][OX2]),$([SiX4H0][OX2])]" +1994,2357,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1 +1995,2360,47 - OCCOH,"[$([OX2H0!R][CX4H2][CX4H2][OX2H1]),$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]" +1996,2362,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1 +1997,2364,52 - Sulphones,"[$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2]),$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1])]" +1998,2365,53 - Oxides,"[$([CX4H2]1[OX2][CX4H2]1),$([CX4H2]1[OX2][CX4H1]1),$([CX4H2]1[OX2][CX4H0]1),$([CX4H1]1[OX2][CX4H1]1),$([CX4H1]1[OX2][CX4H0]1),$([CX4H0]1[OX2][CX4H0]1)]" +1999,2366,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]) +2000,2373,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1] +2001,2374,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1] +2002,2375,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0] +2003,2376,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0] +2004,2377,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0] +2005,2382,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1] +2006,2383,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])] +2007,2384,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1] +2008,2385,17 - H2O (7 - Water),[OX2H2] +2009,2387,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6] +2010,2388,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6] +2011,2389,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1] +2012,2390,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6] +2013,2391,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6] +2014,2392,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6] +2015,2393,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]" +2016,2394,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]" +2017,2396,28 - THF (13 - Ether),[OX2R!r3!$([OX2]C=[OX1])!$([OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1)]([R])[CX4H2R] +2018,2397,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2] +2019,2398,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2] +2020,2399,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2] +2021,2400,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6] +2022,2401,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6] +2023,2402,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6] +2024,2403,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]" +2025,2404,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]" +2026,2406,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1 +2027,2407,39 - C5H4N (18 - Pyridine),"[$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]:[cX3H1]1)]" +2028,2409,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1] +2029,2410,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1] +2030,2411,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1] +2031,2412,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1] +2032,2413,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl +2033,2414,46 - CHCl (21 - CCl),[CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl] +2034,2415,47 - CCl (21 - CCl),[CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl] +2035,2416,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl] +2036,2417,49 - CHCl2 (22 - CCl2),[CX4H1]([!Cl!F])([Cl])[Cl] +2037,2418,50 - CCl2 (22 - CCl2),[CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F] +2038,2419,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl] +2039,2420,52 - CCl3 (23 - CCl3),[CX4H0]([!Cl!F])([Cl])([Cl])[Cl] +2040,2421,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl] +2041,2423,55 - CH3NO2 (26 - CNO2),"[CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]" +2042,2424,56 - CH2NO2 (26 - CNO2),"[CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]" +2043,2425,57 - CHNO2 (26 - CNO2),"[CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]" +2044,2427,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1] +2045,2428,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1] +2046,2429,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1] +2047,2430,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1" +2048,2431,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1] +2049,2432,64 - I (32 - Iodo compounds),[I] +2050,2433,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])] +2051,2434,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0] +2052,2435,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0] +2053,2436,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3] +2054,2437,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1] +2055,2438,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3] +2056,2440,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3] +2057,2441,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2] +2058,2442,74 - CF3 (40 - CF2),[CX4](F)(F)(F)[!Cl!F] +2059,2443,75 - CF2 (40 - CF2),[CX4](F)(F)([!F!Cl!H])([!F!Cl!H]) +2060,2444,76 - CF (40 - CF2),[CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]) +2061,2445,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6] +2062,2446,78 - SiH3 (42 - SiH2),[SiX4H3] +2063,2447,79 - SiH2 (42 - SiH2),[SiX4H2]([!$([OX2])])([!$([OX2])]) +2064,2448,80 - SiH (42 - SiH2),[SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])]) +2065,2449,81 - Si (42 - SiH2),[SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]) +2066,2450,82 - SiH2O (43 - SiO),[SiX4H2][OX2] +2067,2451,83 - SiHO (43 - SiO),[SiX4H1][OX2] +2068,2452,84 - SiO (43 - SiO),[SiX4H0][OX2] +2069,2453,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1 +2070,2454,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F] +2071,2455,87 - CCl2F (45 - CClF),[CX4H0]([Cl])([Cl])([F])[!Cl!F] +2072,2456,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F +2073,2457,89 - HCClF (45 - CClF),[CX4H1](Cl)(F)([!F!Cl]) +2074,2458,90 - CClF2 (45 - CClF),[CX4H0](Cl)(F)(F)[!Cl!F] +2075,2459,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F +2076,2460,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F +2077,2461,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F +2078,2462,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2] +2079,2463,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3] +2080,2464,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2] +2081,2465,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3] +2082,2466,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2] +2083,2467,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2] +2084,2468,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1] +2085,2469,101 - C2H4O2 (47 - OCCOH),"[$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]" +2086,2470,102 - CH3S (48 - CH2S),[CX4H3][SX2H0][*] +2087,2471,103 - CH2S (48 - CH2S),[CX4H2][SX2H0!$([SX2H0]([CX4H2])[CX4H3])][*] +2088,2473,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1 +2089,2474,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1" +2090,2475,107 - C4H3S (50 - Thiophene),"[$([#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H0]=,:1),$([#6X3H1]1-,:[#16X2]-,:[#6X3H0]=,:[#6X3H1]-,:[#6X3H1]=,:1)]" +2091,2477,109 - NCO (51 - NCO),[*][NX2]=[CX2]=[OX1] +2092,2478,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2] +2093,2479,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1] +2094,2480,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1 +2095,2481,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1 +2096,2482,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1 +2097,2483,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1 +2098,2484,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1 +2099,2485,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1 +2100,2486,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]) +2101,2489,phosphorodithionate,[$([SX2H0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0] +2102,2490,"O,O-diethylphosphorodithionate",CCOP(=S)(OCC)SC([*:1]) +2103,2491,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0] +2104,2492,"O,O-dimethylphosphoryl",COP(=O)(O([*:1]))OC +2105,2493,phosphorothionate,[$([OH0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0] +2106,2494,diethylphosphorothionate,CCOP(=S)(O([*:1]))OCC +2107,2495,O-phenyl phenylphosphonothioate,S=P(O([*:1]))(Oc1ccc([*:1])cc1)c1ccccc1 +2108,2496,O-phenyl phosphonothioate,S=P(O([*:1]))(O([*:1]))Oc1ccc([*:1])cc1 +2109,2497,carbamate,[$(N([!H])C(=O)[OH0])]C(=O)[OH0] +2110,2498,"2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-(aminosulfanyl)-N-methylcarbamate",CN(SN([*:1])([*:1]))C(=O)Oc1cccc2CC(C)(C)Oc12 +2111,2499,methyl(propoxysulfanyl) carbamate,CN(SOCCC([*:1]))C(=O)O([*:1]) +2112,2500,phenyl carbamate,O=C(N([*:1]))Oc1ccccc([*:1])1 +2113,2501,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C +2114,2502,dimethylcarbamate,CN(C)C(=O)O([*:1]) +2115,2503,barbiturates,*C1(*)[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]1=O +2116,2504,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12 +2117,2505,Phenothiazine,*-[#7]-1-c2ccccc2-[#16]-c2ccccc-12 +2118,2506,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1 +2119,2507,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1 +2120,2508,"2,4-dichloro-benzene-1,3-dicarbonitrile",N#Cc1c([*:1])c([*:1])c(Cl)c(C#N)c1Cl +2121,2509,R1 - Reactive alkyl halides,"[Br,Cl,I][CX4;CH,CH2]" +2122,2510,R2 - Acid halides,"[S,C](=[O,S])[F,Br,Cl,I]" +2123,2511,R3 - Carbazides,O=CN=[N+]=[N-] +2124,2512,R4 - Sulphate esters,"COS(=O)O[C,c]" +2125,2513,R5 - Sulphonates,"COS(=O)(=O)[C,c]" +2126,2514,R6 - Acid anhydrides,C(=O)OC(=O) +2127,2515,R7 - Peroxides,OO +2128,2516,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F) +2129,2517,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1 +2130,2518,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn +2131,2519,R11 - Isocyanates & Isothiocyanantes,"N=C=[S,O]" +2132,2520,R12 - Triflates,OS(=O)(=O)C(F)(F)F +2133,2521,R13 - Lawesson's reagent and derivatives,P(=S)(S)S +2134,2522,R14 - Phosphoramides,NP(=O)(N)N +2135,2523,R15 - Aromatic azides,cN=[N+]=[N-] +2136,2524,R16 - beta carbonyl quaternary Nitrogen,"C(=O)C[N+,n+]" +2137,2525,R17 - Acylhydrazide,[N;R0][N;R0]C(=O) +2138,2526,"R18 - Quaternary C,Cl,I,P or S","[C+,Cl+,I+,P+,S+]" +2139,2527,R19 - Phosphoranes,C=P +2140,2528,R20 - Chloramidines,[Cl]C([C&R0])=N +2141,2529,R21 - Nitroso,[N&D2](=O) +2142,2530,R22 - P/S Halides,"[P,S][Cl,Br,F,I]" +2143,2531,R23 - Carbodiumide,N=C=N +2144,2532,R24 - Isonitrile,[N+]#[C-] +2145,2533,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O) +2146,2534,R26 - Cyanohydrins,N#CC[OH] +2147,2535,R27 - Acyl cyanides,N#CC(=O) +2148,2536,R28 - Sulfonyl cyanides,S(=O)(=O)C#N +2149,2537,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N +2150,2538,R30 - Azocyanamides,[N;R0]=[N;R0]C#N +2151,2539,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O +2152,2540,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0] +2153,2541,I2 - Compounds with 4 or more acidic groups,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]" +2154,2542,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1] +2155,2543,I4 - Disulphides,SS +2156,2544,I5 - Thiols,[SH] +2157,2545,"I6 - Epoxides, Thioepoxides, Aziridines","C1[O,S,N]C1" +2158,2546,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]) +2159,2547,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]) +2160,2548,I9 - Hydrazothiourea,N=NC(=S)N +2161,2549,I10 - Thiocyanate,SC#N +2162,2550,I11 - Benzylic quaternary Nitrogen,cC[N+] +2163,2551,I12 - Thioesters,"C[O,S;R0][C;R0](=S)" +2164,2552,I13 - Cyanamides,N[CH2]C#N +2165,2553,I14 - Four membered lactones,C1(=O)OCC1 +2166,2554,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH] +2167,2555,I16 - Betalactams,N1CCC1=O +2168,2556,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1 +2169,2557,N2 - Polyenes,C=CC=CC=CC=C +2170,2558,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2 +2171,2559,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21 +2172,2560,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O +2173,2561,N6 - Monensin derivatives,O1CCCCC1C2CCCO2 +2174,2562,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3 +2175,2563,N8 - Squalestatin derivatives,C12OCCC(O1)CC2 +2176,2564,"A1 - e.g., carboxylic acid","[OH1][P,C,S](=O)" +2177,2565,"A2 - e.g.,imide","[NH1]([P,S]=O)([P,S]=O)" +2178,2567,A4,[OH1]C1=NC=NO1 +2179,2568,A5,[NH1]1C=NOS1=O +2180,2569,A6,[OH1]C1=NC(=O)CC1=O +2181,2570,A7,[OH1]C1NC(=O)C(=O)C1 +2182,2571,A8,[nH1]1ncoc1=O +2183,2572,A9,[OH1]C1=NN=CO1 +2184,2573,A10,[nH1]1[nH]cnc1=O +2185,2574,A11,[OH1]C1=N[NH1]C=N1 +2186,2575,A12,[OH1]C1=NOC=C1 +2187,2576,A13,[nH1]1occc1=O +2188,2577,A14,[OH1]c1oncc1 +2189,2578,A15,[nH1]1ccc(=O)o1 +2190,2579,A16 - tetrazole,[nH1]nnn +2191,2580,A17,[nH1](n)nn +2192,2581,A18,[OH1]C1=NC(=O)NO1 +2193,2582,A19,[OH1]C1=NC(=O)ON1 +2194,2583,A20,[nH1]1cnnc1C(F)(F)F +2195,2584,A21,[nH1]1cnc(n1)C(F)(F)F +2196,2585,A22,[nH1]1C(=O)CC(=O)O1 +2197,2586,A23,[OH1]C1=CC(=O)NO1 +2198,2587,A24,[OH1]C1=CC(=O)ON1 +2199,2588,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O +2200,2589,A26,[OH1]C1=NS(=O)(=O)c2ccccc21 +2201,2590,A27,[OH1]C1=NC(=O)c2ccccc21 +2202,2591,A28,[OH1]C1=COC=CC1=O +2203,2592,A29,[OH1]C1=NSN=C1 +2204,2593,A30 - hyroxamic acid,[OH1]NC(=O) +2205,2594,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F +2206,2595,A32 - aryl sulphonamide,[NH](c)S(=O)=O +2207,2596,A33 - phenol,"[OH1]c1c[c,n]ccc1" +2208,2598,B1 - primary amine,[NH2][CX4] +2209,2599,B2 - secondary amine,[NH]([CX4])[CX4] +2210,2600,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4] +2211,2601,B4SUB,"[C,c](=N)N" +2212,2602,B5EXC,"[C,c](=N)N[C,S](=O)" +2213,2603,B6,"[$([C,c](=N)N);!$([C,c](=N)N[C,S](=O))]" +2214,2604,B7EXC,n(:c)(:c):a +2215,2605,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1 +2216,2606,B8EXC,"[N,n;+1]" +2217,2607,B9,"[$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]" +2218,2609,E1 - alkyl and aryl ketones and aldehydes,"[C;H1](=[O,S])[C,c]" +2219,2610,"E2 - e.g., carboxylic esters","[C,P;H1](=[O,S])[O,S]" +2220,2611,"E3 - e.g., carbonates","[C](=O)([C,c,O,S])[C,c,O,S]" +2221,2612,E4EXC,C(=O)[OH1] +2222,2613,E5EXC,C(=O)[SH1] +2223,2614,E6,"C(=[O,S])(N)Oc" +2224,2615,"E7 - e.g., aryl carbamates","C1(=O)NS(=O)(=O)[C,c]=,:[C,c]1" +2225,2616,E8SUB,"P(=O)[O,S]" +2226,2617,E9EXC,P[OH1] +2227,2618,E10,"[$(P(=O)[O,S]);!$(P[OH1])]" +2228,2619,E11,c(=O)(~c)~c +2229,2620,E12EXC,"[$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)]" +2230,2621,E12,"[$(c(=O)(~c)~c);!$([$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)])]" +2231,2622,E13 - imides,C(=O)-N-C=O +2232,2624,N1 - pimary amines,[NX3H2][CX4] +2233,2625,N2 - secondary amines,[NX3H]([CX4])[CX4] +2234,2626,N4EXC,"N=[O,C,N,S]" +2235,2627,N5EXC,"N-[C,c,N]=[C,c,N,n,O,S]" +2236,2628,N6,"[OH1][C,c,N;!$(C=O)]" +2237,2629,N7EXC,[OH1]C=C +2238,2630,N8EXC,"[OH1]NC=[O,S]" +2239,2631,N9,"[$([NX3H2]!:c),$([NX3H1]([CX4])!:c),$([NX3H0]([CX4])([CX4])!:c)]" +2240,2632,NUC,"[$([NH2][CX4]),$([NH]([CX4])[CX4]),$([OH1][C,c,N;!$(C=O)]),$([$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]);!$(N=[O,C,N,S]);!$(N-[C,c,N]=[C,c,N,n,O,S]);!$([OH1]C=C);!$([OH1]NC=[O,S])]" +2241,2633,> 2 ester groups,"C(=O)O[C,H1].C(=O)O[C,H1].C(=O)O[C,H1]" +2242,2634,2-halo pyridine,"n1c([F,Cl,Br,I])cccc1" +2243,2635,Acid halide,"C(=O)[Cl,Br,I,F]" +2244,2636,Acyclic C=C-O,C=[C!r]O +2245,2637,Acyl cyanide,N#CC(=O) +2246,2638,Acyl hydrazine,C(=O)N[NH2] +2247,2640,Aliphatic long chain,[R0;D2][R0;D2][R0;D2][R0;D2] +2248,2643,Aniline,c1cc([NH2])ccc1 +2249,2644,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1 +2250,2645,Azido group,N=[N+]=[N-] +2251,2646,Azo group,N=N +2252,2647,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1 +2253,2648,Benzidine,"[cR2]1[cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2][cR2]1[cR2]2[cR2][cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2]2" +2254,2649,Betaketo/anhydride,"[C,c](=O)[CX4,CR0X3,O][C,c](=O)" +2255,2650,Biotin analogue,C12C(NC(N1)=O)CSC2 +2256,2651,Carbo cation/anion,"[C+,c+,C-,c-]" +2257,2652,Catechol,"c1c([OH])c([OH,NH2,NH])ccc1" +2258,2653,Charged oxygen or sulfur atoms,"[O+,o+,S+,s+]" +2259,2654,Chinone (1),"C1(=[O,N])C=CC(=[O,N])C=C1" +2260,2655,Chinone (2),"C1(=[O,N])C(=[O,N])C=CC=C1" +2261,2656,Conjugated nitrile group,C=[C!r]C#N +2262,2657,Crown ether,"[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]" +2263,2658,Cumarine,c1ccc2c(c1)ccc(=O)o2 +2264,2659,Cyanamide,N[CH2]C#N +2265,2660,Cyanate/aminonitrile/thiocyanate,"[N,O,S]C#N" +2266,2661,Cyanohydrins,N#CC[OH] +2267,2662,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1 +2268,2663,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1 +2269,2664,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1 +2270,2665,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1 +2271,2666,Diaminobenzene (1),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])c([N+R0,NX3R0,nX3R0])[cR2][cR2]1" +2272,2667,Diaminobenzene (2),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2]c([N+R0,NX3R0,nX3R0])[cR2]1" +2273,2668,Diaminobenzene (3),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2][cR2]c1([N+R0,NX3R0,nX3R0])" +2274,2669,Diazo group,[N!R]=[N!R] +2275,2670,Diketo group,"[C,c](=O)[C,c](=O)" +2276,2671,Disulphide,SS +2277,2672,Enamine,[CX3R0][NX3R0] +2278,2673,Ester of HOBT,C(=O)Onnn +2279,2674,Four member lactones,C1(=O)OCC1 +2280,2675,Halogenated ring (1),"c1cc([Cl,Br,I,F])cc([Cl,Br,I,F])c1[Cl,Br,I,F]" +2281,2676,Halogenated ring (2),"c1ccc([Cl,Br,I,F])c([Cl,Br,I,F])c1[Cl,Br,I,F]" +2282,2677,Heavy metal,"[Hg,Fe,As,Sb,Zn,Se,se,Te,B,Si]" +2283,2678,Het-c-het not in ring,"[NX3R0,NX4R0,OR0,SX2R0][CX4][NX3R0,NX4R0,OR0,SX2R0]" +2284,2679,Hydantoin,C1NC(=O)NC(=O)1 +2285,2682,Hydroxamic acid,C(=O)N[OH] +2286,2683,Imine,C=[N!R] +2287,2687,Isolated alkene,"[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]=[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]" +2288,2688,Ketene,C=C=O +2289,2689,"Methylidene-1,3-dithiole",S1C=CSC1=S +2290,2690,Michael acceptor (1),"C=!@CC=[O,S]" +2291,2691,Michael acceptor (2),"[$([CH]),$(CC)]#CC(=O)[C,c]" +2292,2692,Michael acceptor (3),"[$([CH]),$(CC)]#CS(=O)(=O)[C,c]" +2293,2693,Michael acceptor (4),C=C(C=O)C=O +2294,2694,Michael acceptor (5),"[$([CH]),$(CC)]#CC(=O)O[C,c]" +2295,2695,N oxide,"[NX4,nX3][OX1]" +2296,2696,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O +2297,2697,N-c-halo,"NC[F,Cl,Br,I]" +2298,2698,N-halo,"[NX3,NX4][F,Cl,Br,I]" +2299,2699,N-hydroxylpyridine,n[OH] +2300,2700,Nitro group,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]" +2301,2701,N-nitroso,[#7]-N=O +2302,2702,Oxime (1),"[C,c]=N[OH]" +2303,2703,Oxime (2),"[C,c]=NOC=O" +2304,2704,Oxygen-nitrogen single bond,"[OR0,NR0][OR0,NR0]" +2305,2705,Perfluorinated chain,[CX4](F)(F)[CX4](F)F +2306,2706,Peroxide,OO +2307,2707,Phenol ester,c1ccccc1OC(=O)[#6] +2308,2708,Phenyl carbonate,c1ccccc1OC(=O)O +2309,2709,Phosphor,P +2310,2710,Phthalimide,"[cR,CR]~C(=O)NC(=O)~[cR,CR]" +2311,2711,Polycyclic aromatic hydrocarbon (1),"a1aa2a3a(a1)[a,A]=,:[a,A]-,:[a,A]=,:[a,A]3A=AA2" +2312,2712,Polycyclic aromatichydrocarbon (2),a21aa3a(aa1aaaa2)aaaa3 +2313,2713,Polycyclic aromatichydrocarbon (3),a31a(a2a(aa1)aaaa2)aaaa3 +2314,2714,Polyene,[CR0]=[CR0][CR0]=[CR0] +2315,2715,Quaternary nitrogen (1),"[s,S,c,C,n,N,o,O]~[nX3+,NX4+](~[s,S,c,C,n,N])~[s,S,c,C,n,N]" +2316,2716,Quaternary nitrogen (2),"[s,S,c,C,n,N,o,O]~[n+,N+](~[s,S,c,C,n,N,o,O])(~[s,S,c,C,n,N,o,O])~[s,S,c,C,n,N,o,O]" +2317,2717,Quaternary nitrogen (3),[*]=[N+]=[*] +2318,2718,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2 +2319,2719,Silicon halogen,"[Si][F,Cl,Br,I]" +2320,2720,Stilbene,c1ccccc1C=Cc2ccccc2 +2321,2721,Sulfinic acid,"[SX3](=O)[O-,OH]" +2322,2722,Sulfonic acid,"[C,c]S(=O)(=O)O[C,c]" +2323,2724,Sulfonyl cyanide,S(=O)(=O)C#N +2324,2725,Sulfur oxygen single bond,[SX2]O +2325,2726,Sulphate,OS(=O)(=O)[O-] +2326,2727,Sulphur nitrogen single bond,[SX2H0][N] +2327,2728,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2) +2328,2729,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2) +2329,2730,Thiocarbonyl group,"[C,c]=S" +2330,2732,Thiol (1),[S-] +2331,2733,Thiol (2),[SH] +2332,2734,Three-membered heterocycle,"*1[O,S,N]*1" +2333,2735,Triflate,OS(=O)(=O)C(F)(F)F +2334,2736,Triphenyl methylsilyl,"[SiR0,CR0](c1ccccc1)(c2ccccc2)(c3ccccc3)" +2335,2737,Triple bond,C#C +2336,2738,Aromatic NO2,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-c(:*):*" +2337,2739,Deuterium,[2H] +2338,2740,C13,[13#6] +2339,2741,2-Chloropyridine,n1c(cccc1)Cl +2340,2743,"Si,B,Se atoms","[Si,B,Se]" +2341,2744,Hetero imides,[!#6]-[CH2]-N1C(=O)CCC(=O)1 +2342,2745,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O +2343,2746,Acyclic imines,"C-!@[NX2]=[C!R,#1]-C" +2344,2747,Alkyl esters of S or P,"[S,P](=O)OC" +2345,2748,Ugly P compounds,"P(=[O,S])[C,N]([C,N])[C,N]" +2346,2749,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]" +2347,2750,Acyclic N-C-N,N-!@[CX4]-!@N +2348,2751,Acyclic N-S,N-!@[SX2]-* +2349,2754,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O +2350,2755,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O +2351,2756,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O +2352,2757,Carbamate include di-substitued N,OC(=O)-!@[NX3] +2353,2758,Acyl halide,"O=C-[F,Cl,Br,I]" +2354,2760,Alpha halo carbonyl,"O=C-C-[F,Cl,Br,I]" +2355,2761,Sufonyl halide,"S(=O)(=O)-[F,Cl,Br,I]" +2356,2762,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2] +2357,2763,26,N-C(=S)-N +2358,2764,Terminal vinyl,[CH2D1]=[CD2]-!@* +2359,2765,28,S=P~* +2360,2766,Thio cyanates,S-C#N +2361,2768,Thionyl,[Sv4](=O)(-!@[!#1])-!@[!#1] +2362,2769,N-Haloamines,"N-[F,Cl,Br,I]" +2363,2770,N-C-Hal or cyano methyl,"N-C-[F,Cl,Br,I,$(C#N)]" +2364,2771,Alpha beta-unsaturated ketones; center of Michael reactivity,"[$(C#N),$(N(~O)~O),$(C=O),$(S(=O)=O),$(C(F)(F)F),Cl][C!H0]=[C!H0]" +2365,2772,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2] +2366,2773,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2] +2367,2774,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2] +2368,2777,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)] +2369,2778,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])] +2370,2779,42,S-S +2371,2780,43,O~O +2372,2782,Aziridine-like N in 3-membered ring,N~1~*~*1 +2373,2784,Aryl iodide,I-c:* +2374,2785,Aryl bromide,Br-c:* +2375,2786,Multiple aromatic rings,a1aaa2a(a1)aaa(a2):a +2376,2788,S/PO3 groups,"[P,S](~O)(~O)~O" +2377,2789,Adamantyl,C12CC3CC(C1)CC(C2)C3 +2378,2790,Too many cyano groups (>1),C#N.C#N +2379,2791,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1] +2380,2792,Amino acid,[NH2][CX4]C(=O)O +2381,2793,Chlorates,Cl~O +2382,2794,High halogen content (>3),"[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I]" +2383,2795,Filter1_2_halo_ether,"[Cl,Br,I][CX4][CX4][$([O,S,N]*),Cl,Br,I]" +2384,2796,Filter2_acyl_phosphyl_sulfonyl_halide,"[C,S,P](=O)[F,Cl,Br,I]" +2385,2797,Filter3_allyl_halide,"[F,Cl,Br,I][CX4]C=C" +2386,2798,Filter4_alpha_halo_carbonyl,"[Br,Cl,I][C!H0]C=[O,S]" +2387,2799,Filter5_azo,"[!#7,#1]~[NX2R0]=[NX2R0]~[!#7,#1]" +2388,2800,Filter6_benzyl_halide,"[Br,Cl,I][CX4]c" +2389,2801,Filter7_diazo,[!#7]~[NX2]~[NX1] +2390,2802,Filter8_thio_isocyanat_diimin,"N=C=[N,O,P,S]" +2391,2803,Filter9_metal,"[!#1!#6!#7!#8!#9!#15!#16!#17]~[*,#1]" +2392,2804,Filter10_Terminal_vinyl,"[CH2]=[CH][N,O,P,S;R0]" +2393,2805,Filter11_nitrosamin,[NR0]~[NX2]~[OX1] +2394,2806,Filter12_nitroso,"[*,#1]~[NX2]~[OX1]" +2395,2807,Filter13_PS_double_bond,"S=P~[*,#1]" +2396,2808,Filter14_thio_oxopyrylium_salt,"c1ccc[s,o;X2]c1" +2397,2809,Filter15_thiosulfate,[SX4](~S)(~O)(~O)~* +2398,2810,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6] +2399,2811,Filter17_trialkyl_phosphin2,[PX4](~[!O!S])([#6])([#6])[#6] +2400,2812,Filter18_oxime_ester,"[!#7,#1]C=NO[C,S,P](=O)*" +2401,2813,Filter19_hydroxyimide_ester,O=C[NX3](C=O)OC(=O)* +2402,2814,Filter20_hydrazine,[Nv3X3][Nv3X3!H0] +2403,2815,Filter21_cyanhydrin,[NX1]#C[CX4][OH] +2404,2816,Filter22_sulfonium_salt,*[SX3](*)* +2405,2817,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O +2406,2818,Filter24_react_imide,"*C([F,Cl,Br,I,$(OS(=O)(=O)*)])=[NX2]*" +2407,2819,Filter25_sulfonyl_halide,"*S(=O)(=O)[F,Cl,Br,I]" +2408,2820,Filter26_alkyl_halide,"AA[CH2][F,Cl,Br,I,$(OS(=O)(=O)*)]" +2409,2821,Filter27_anhydride,"*[C,S](=O)O[C,S](=O)*" +2410,2822,Filter28_halo_pyrimidine,"c1nc(ncc1)[Br,I]" +2411,2823,Filter29_thioester,"CC(=[OX1,SX1,NH])[SX2][*,#1]" +2412,2824,Filter30_beta_halo_carbonyl,"[#6,#1]C(=O)CC[Br,I]" +2413,2825,Filter31_SO_bond,"[*,#1][SX2R0]O[*,#1]" +2414,2826,Filter32_OO_bond,"[*,#1][OR0]O[*,#1]" +2415,2827,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2] +2416,2828,Filter34_isotope,"[2#1,3#1,13C,14C,15N,125I,23F,22Na,32P,33P,35S,45Ca,57Co,103Ru,141Ce]" +2417,2829,Filter35_PP_bond,P-P +2418,2830,Filter36_SS_double_bond,S=S +2419,2831,Filter37_silicate,[Si]~O +2420,2832,Filter38_aldehyde,O=[CH]* +2421,2833,Filter39_imine,C[CR0]=[NR0][*!O] +2422,2834,Filter40_epoxide_aziridine,"C1C[N,S,O]1" +2423,2835,Filter41_12_dicarbonyl,*C(=O)C(=O)* +2424,2836,Filter42_12_dicarbonyl_tautomer,[*!$(C[OH])]=C([OH])C(=O)* +2425,2837,Filter43_michael_acceptor_sp1,C#CC=O +2426,2838,Filter44_michael_acceptor2,"[#6,#1,OH0][C!$(C1(=O)C=CC(=O)C=C1)](=O)C=[C!$(C[Nv3X3,OH])]" +2427,2839,Filter45_allyl_halide2,"[Br,Cl,I][CX4]C=[C,N,P]" +2428,2840,Filter46_nhalide,"N[F,Cl,Br,I]" +2429,2841,Filter47_SO2F,O=S(=O)(*)F +2430,2842,Filter48_FOSO,O=S(*)OF +2431,2843,Filter49_halogen,"[*,#1]~[F,Cl,Br,I]~[*,#1]" +2432,2844,Filter50_grignard,"C[Mg][F,Cl,Br,I]" +2433,2845,Filter51_PN3,N[PX3](N)N +2434,2846,Filter52_NC_haloamine,"NC[F,Cl,Br,I]" +2435,2847,Filter53_para_quinones,O=C1C=CC(=O)C=C1 +2436,2848,Filter56_SS_bond,S-S +2437,2849,Filter57_polyphenol1,Oc1cc(O)cc(O)c1 +2438,2850,Filter58_polyphenol2,Oc1c(O)cc(O)cc1 +2439,2851,Filter59_phoshorous_ylide,C=P +2440,2852,Filter60_Acyclic_N-S,N!@[SX2] +2441,2853,Filter61_phosphor_halide_and_P_S_bond,"[#15]~[F,Cl,Br,I,#16]" +2442,2854,Filter62_oxo_thio_halide,"[O,S]~[Cl,Br,I]" +2443,2855,Filter63_polyaromatic,a1aaaa2ccc3ccccc3c12 +2444,2856,Filter64_halo_ketone_sulfone,"[#6][C,S](=[O,S])C[F,Cl,Br,I]" +2445,2857,Filter65_alkyl_sulfonate,"[#6][P,S](~[OX1])(~[OX1])O[C!H0]" +2446,2858,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F) +2447,2859,Filter67_S_or_O_C_triplebond_N,"[O,S]C#N" +2448,2860,Filter68_anthracene_acridine,a1aaac2cc3ccccc3cc12 +2449,2861,Filter69_thio_carbonate,"[O,S]C(=[O,S])[O,S]" +2450,2862,Filter70_AlkylCN2,*(C#N)C#N +2451,2863,Filter71_thio_anhydride,"*C(=[O,S])[O,S]C(=[O,S])*" +2452,2864,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH] +2453,2865,Filter73_thio_ketone,CC(=S)C +2454,2866,Filter74_thiol,*[SX2H] +2455,2867,Filter75_alkyl_Br_I,"[C!H0][Br,I]" +2456,2868,Filter76_S_ester,CC(=S)O +2457,2869,Filter77_alkyl_NO2,"[*!#7]~[#6]-,=CN(~O)(~O)" +2458,2870,Filter78_bicyclic_Imide,*~@C1C(=O)NC(=O)C(~@*)1 +2459,2871,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1 +2460,2872,Filter80_Thioepoxide_aziridone,"[N,S]1[C,N,S][C,N,S]1" +2461,2873,Filter81_Thiocarbamate,"S!@C(=!@[O,S])!@[#7]" +2462,2874,Filter82_pyridinium,"[c,n]1[c,n][c,n][c,n][c,n]n(C)1" +2463,2875,Filter83_per_halo_chain,"[F,Cl,Br,I]C-,=;!@C([F,Cl,Br,I])-,=;!@C([F,Cl,Br,I])" +2464,2876,Filter84_nitrogen_mustard,"[N,P,Se,S][C!H0]C[Br,Cl,I]" +2465,2877,Filter85_keto_acrylonitrile,*C(=O)C(=!@[C!H0])C#N +2466,2878,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)] +2467,2879,Filter87_crowns,"[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[O,N]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@C" +2468,2880,Filter88_ene_sulfone,[C!H0]=CS(=O)(=O)* +2469,2881,Filter89_hydroxylamine,"[*!$(C=O)]!@N!@O[*,#1]" +2470,2882,Filter90_N_double_bond_S,N=!@S +2471,2883,Filter92_trityl,*(c1ccccc1)(c1ccccc1)(c1ccccc1) +2472,2884,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7] +2473,2885,Filter94_2_halo_pyridine,"c1nc(ccc1)[Br,I,Cl,F]" +2474,2886,Anhydride,C(=O)OC(=O) +2475,2887,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1 +2476,2888,Any carbazide,O=*N=[N+]=[N-] +2477,2889,HOBT ester,C(=O)Onnn +2478,2890,Aromatic azide,cN=[N+]=[N-] +2479,2891,Imine2,"[#6,#8,#16]-[CH1]=[NH1]" +2480,2893,Azocyanamide,[N;R0]=[N;R0]C#N +2481,2894,Cyanohydrin,N#CC[OH] +2482,2897,Chloramidine,[Cl]C([C&R0])=N +2483,2898,P/S halide,"[P,S][F,Cl,Br,I]" +2484,2899,Quaternary,"[C+,Cl+,I+,P+,S+]" +2485,2900,Unacceptable atoms,[!#6;!#7;!#8;!#16;!#1;!#3;!#9;!#11;!#12;!#15;!#17;!#19;!#20;!#30;!#35] +2486,2901,Triacyloxime,C(=O)N(C(=O))OC(=O) +2487,2902,b-Carbonyl quaternary nitrogen,"C(=O)CC[N+,n+]" +2488,2903,Benzylic quaternary nitrogen,cC[N+] +2489,2904,Phosphorane,C=P +2490,2905,Lawesson reagent derivatives,P(=S)(S)S +2491,2906,Cyanophosphonate,P(OCC)(OCC)(=O)C#N +2492,2907,Sulfonate,"COS(=O)(=O)[C,c]" +2493,2908,Heteroaryl sulfonate,"a-S(=O)(=O)-O[$([a&!#6]),$(c[a&!#6]),$(cc[a&!#6]),$(ccc[a&!#6]),$(cccc[a&!#6]),$(ccccc[a&!#6])]" +2494,2909,Sulfate ester,"COS(=O)O[C,c]" +2495,2911,Polyacidic,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]" +2496,2913,Thiol,[SH] +2497,2914,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2 +2498,2915,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1 +2499,2916,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]) +2500,2917,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]) +2501,2918,Allene,*=C=* +2502,2919,Azide,"[$(*-[NX2-]-[NX2+]#[NX1]),$(*-[NX2]=[NX2+]=[NX1-]),$(N=N=N)]" +2503,2920,Azoalkanal,[N;R0]=[N;R0]CC=O +2504,2921,Hydrazothiourea,N=NC(=S)N +2505,2924,Hemiacetal,[#6]-O[CH1](-[#6])[OH1] +2506,2927,Ester,[#6]-C(=O)O-[#6] +2507,2928,Imine 1,"[#6,#8,#16]-C(=[NH1])[#6,#8,#16]" +2508,2929,Imine 3,C=[NH] +2509,2930,Thioketone,CC(=S)C +2510,2932,Thionoester,COC(=S)C +2511,2933,Thioamide,CC(=S)N +2512,2936,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0] +2513,2937,Long aliphatic chain,"[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]" +2514,2938,Unbranched chain,"[$([A&D2]),$([A&D1])]!@[A&D2]!@[A&D2]!@[A&D2]!@[A&D2]!@[$([A&D2]),$([A&D1])]" +2515,2940,Dye 25,acC=&!@Cca +2516,2941,Isonitrile,[N+]#[C-] +2517,2942,Thiocyanate,SC#N +2518,2944,Dye 16 (1),"c[$([NX3](=O)=O),$([NX3+](=O)[O-])]" +2519,2945,Nitro aromatic 2+,"a-[$([NX3](=O)=O),$([NX3+](=O)[O-])].a-[$([NX3](=O)=O),$([NX3+](=O)[O-])]" +2520,2946,Dye 29,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-caac-[$(N(C)C),$([NH]C),$([NH2])]" +2521,2947,Dye 1 (1),"c1cccc(C(=O)[C,c]([#7])=,:[C,c]([#7])C2(=O))c12" +2522,2948,Dye 7,"N=C1[#6]:,=[#6]C(=[C,N])[#6]:,=[#6]1" +2523,2949,Dye 11,"*=,:[#6]C([#6]=,:*)[#6]=,:*" +2524,2950,Dye 9,ac-*=&!@*-&!@C(=O)-&!@ca +2525,2951,Dye 32,"c1cccc2C(=O)C(C:,=*)C(=O)c12" +2526,2952,Dye 6,c12cccc(C(=O)C(ca)C(=O)3)c2c3ccc1 +2527,2953,Dye 22,NS(=O)(=O)c1cccc([#7])c1 +2528,2954,Dye 2,OCccCO +2529,2955,Dye 26,c1ccccc1-n2nnnc2[CH2]* +2530,2957,Perhalo_ketone,"O=CC(-[F,Cl,Br,I])([F,Cl,Br,I])-[F,Cl,Br,I]" +2531,2958,Beta halo carbonyl,"O=CCC[F,Cl,Br,I]" +2532,2959,4-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[n]:[c,n]:[c,n]1" +2533,2960,2-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[c,n]:[c,n]:[n]1" +2534,2961,Hetero_hetero,"*[N,S,O]-&!@[N,S,O][#6]" +2535,2963,Disulfide,SS +2536,2966,Vinyl michael acceptor1,"[#6]-[CH1]=C-C(=O)[#6,#7,#8]" +2537,2967,Vinyl michael acceptor2,"[CH2]=C-C(=O)[#6,#7,#8]" +2538,2968,Michael acceptor 5,N#CC(=C)C#N +2539,2969,Michael acceptor 6,"[#6,#7]-&!@[#6](=&!@[CH])-&!@C(=O)-&!@[C,N,O,S]" +2540,2970,Alkynyl michael acceptor1,"[#6]-C#CC(=O)[#6,#7,#8]" +2541,2971,Alkynyl michael acceptor2,"[CH1]#CC(=O)-[#6,#7,#8]" +2542,2972,Nitroalkane,"C[$([NX3](=O)=O),$([NX3+](=O)[O-])]" +2543,2974,Nitrate,"[#6]-O-[$([NX3](=O)=O),$([NX3+](=O)[O-])]" +2544,2975,Oxalyl,O=C-&!@C=O +2545,2976,Dipeptide,*-C(=O)-&!@[NH]-C-&!@C(=O)-&!@[NH]-* +2546,2977,Quaternary nitroxy,C[N+](-[O-])(C)C +2547,2978,Triphenylphosphine,a-P(-a)-a +2548,2979,Phosphoric acid,[OH]-P(=O)(-O)-* +2549,2980,Phosphoric ester,COP(=O)(-*)O +2550,2981,Di/triphosphate,P(=O)([OH])OP(=O)[OH] +2551,2982,Tri phosphoric esters,[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6] +2552,2983,Phosphoramide,NP(=O)(N)N +2553,2984,Phenalene,c1(c)c2c(c)cccc2ccc1 +2554,2985,Poly(azo(anthracene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1[c,n]c3:[c,n]:[c,n]:[c,n]:[c,n]:c3[c,n]2" +2555,2986,Poly(azo(phenanthrene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1:[c,n]:[c,n]:c3:[c,n]:[c,n]:[c,n]:[c,n]:c23" +2556,2987,Dye 31,a1aaac2ac3acac4aaac(c34)c12 +2557,2988,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O +2558,2989,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1 +2559,2990,"Epoxide, aziridine, thioepoxide","C1[O,S,N]C1" +2560,2991,Propiolactone,C1(=O)OCC1 +2561,2992,b-Lactam,N1CCC1=O +2562,2993,Cycloheximide,O=C1CCCC(N1)=O +2563,2994,Aromatic sulfonic ester,"[#6,#7]-S(=O)(=O)Oc" +2564,2995,Quinone,"[$([o,n]=c1ccc(=[o,n])cc1),$([O,N]=C1C=CC(=[O,N])C=C1),$([O,N]=C1[#6]:,=[#6]C(=[O,N])[#6]:,=[#6]1)]" +2565,2996,Saponin,O1CCCCC1OC2CCC3CCCCC3C2 +2566,2997,Monensin,O1CCCCC1C2CCCO2 +2567,2998,Squalestatin,C12OCCC(O1)CC2 +2568,2999,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3 +2569,3000,Cytochalasin,O=C1NCC2CCCCC21 +2570,3001,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1 +2571,3002,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]) +2572,3003,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]) +2573,3004,Acid_anhydrides,C(=O)OC(=O) +2574,3005,Acid_halides,"[S,C](=[O,S])[F,Br,Cl,I]" +2575,3006,Acridine,c1c2cc4ccccc4nc2ccc1 +2576,3007,Active_phosphate,"P(=S)([OH1,O$(O[#6])])([OH1,O$(O[#6])])[S,O]" +2577,3008,Acyl_cyanide,C(=O)-C#N +2578,3009,Adjacent_ring_double_bonds,[*;R]=[*;R]=[*;R] +2579,3011,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F +2580,3012,Alkyl_halides,"[Br,Cl,I][CX4;CH,CH2]" +2581,3013,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]" +2582,3015,Alpha_halo_carbonyl,"[C;!$(C[N])](=O)!@[C;h1,h2;H1,H2][F,Cl,Br,I]" +2583,3017,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21 +2584,3018,Aminonitrile,NC#N +2585,3020,Any_carbazide,O=*N=[N+]=[N-] +2586,3021,Aromatic_azides,"c[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]" +2587,3022,Azanitrone,N=[N+]([O-])C +2588,3023,Azoalkanals,[N;R0]=[N;R0]CC=O +2589,3024,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2 +2590,3026,B-carbonyl_quaternary_nitrogen,"C(=O)CC[N+,n+]" +2591,3027,Benzylic_quaternary_nitrogen,"cC[N+,NX4]" +2592,3028,Beta-carbonyl_quaternary_nitrogen,"C(=O)C[N+,n+,NX4,nX4]" +2593,3029,Beta-fluoro-ethyl-on,"[C;H2$(CF),H1$(C(F)F)]!@[CH2][N,O]" +2594,3030,Biotin_analogue,C12C(NC(N1)=O)CSC2 +2595,3031,Carbazides,"C(=O)[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]" +2596,3033,CCl3-CHO_releasing,"C(Cl)(Cl)(Cl)C([O,S])[NX3]" +2597,3035,Conjugated_dithioether,SC(=[!r])S +2598,3036,Crown_ether_12cro4,O1CCOCCOCCOCC1 +2599,3037,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1 +2600,3038,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1 +2601,3039,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1] +2602,3043,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH] +2603,3044,Diacetylene,C#CC#C +2604,3045,Diazoalkane,C=[N+]=[N-] +2605,3046,Diazonium_salt,[N+]#N +2606,3047,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O) +2607,3048,Dinitrobenzene_1,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc1" +2608,3049,Dinitrobenzene_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])c1" +2609,3050,Dinitrobenzene_3,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1" +2610,3052,Dithiocarbamate,NC(=S)S +2611,3053,Dithiole-2-thione,S1SC=CC1=S +2612,3054,Dithiole-3-thione,S1C=CSC1=C +2613,3055,Dithiomethylene_acetal,S[C;!$(C=*)]S +2614,3056,Enyne,C=!@CC#C +2615,3057,"Epoxides,_thioepoxides,_aziridines","C1[O,S,N]C1" +2616,3058,Ester_of_HOBT,C(=O)Onnn +2617,3059,Flavin,"c1cccc(NC(=NC(=[N,S,O])NC(=O)3)C3=N2)c12" +2618,3060,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12 +2619,3061,Fluorinated_carbon_1,C(C(CF)F)F +2620,3062,Fluorinated_carbon_2,C(C(F)F)(F)F +2621,3063,Four_member_lactones,C1(=O)OCC1 +2622,3064,Geminal_amines,[NH1;!r][CX4][NH1;!r] +2623,3065,Geminal_dinitriles,N#CCC#N +2624,3066,"Halo-pyridine, -diazoles and -triazoles","[Cl,Br,I]c1[c,n][c,n][c,n][c,n]n1" +2625,3068,Imidazolium,c1[n+]([#6])ccn1([#6]) +2626,3070,Imines_(not_ring),"[#6][CR0](=[NR0,OR0])[#6]" +2627,3071,Isocyanates_and_isothiocyanates,"N=C=[S,O]" +2628,3074,Lawesson_reagent_derivatives,P(=S)(S)S +2629,3076,Michael_phenyl_ketone,c1ccccc1C(=O)C=!@CC(=O)!@* +2630,3078,Nitrobenz-azadiazole_1,"c1ccc(n[o,s]n2)c2c1[$([NX3](=O)=O),$([NX3+](=O)[O-])]" +2631,3079,Nitrobenz-azadiazole_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc(n[o,s]n2)c2c1" +2632,3080,Nitrosamine,N-[N;X2](=O) +2633,3082,Noname,"N1=C[S,NH1]C(=[C,N,P][C,N,O,P])C1(=O)" +2634,3083,N-oxide_aliphatic,[N+!$(N=O)][O-X1] +2635,3084,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0] +2636,3085,Orthoester,C(O)(O)[OH] +2637,3086,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1 +2638,3087,Oxobenzothiepine,C1(=O)C=CCSC=C1 +2639,3088,P_or_S_halides,"[P,S][Cl,Br,F,I]" +2640,3089,P-aminoaryl_diazo,Nc1aaa(N!@=N)aa1 +2641,3090,PCP,PCP +2642,3091,Paranitrophenyl_esters,"C(=O)Oc1ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1" +2643,3092,Pentahalophenyl,"c1c([F,Cl])c([F,Cl])c([F,Cl])c([F,Cl])c1([F,Cl])" +2644,3093,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F) +2645,3095,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2 +2646,3096,Phenylester,C(=O)!@Oc1ccccc1 +2647,3097,Phosphonate_esters,[#6]P(=O)(~O)O[#6] +2648,3098,Phosphoramides,NP(=O)(N)N +2649,3100,Phosphorus_halide,"[S,P][F,Cl,Br,I]" +2650,3102,Polyenes,C=CC=CC=CC=C +2651,3103,Polyene_chain_between_aromatics,cC=CC=CC=Cc +2652,3104,Polyines,CC#CC#CC +2653,3105,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13 +2654,3106,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13 +2655,3107,Polysulfide,*[SX2][SX2][SX2]* +2656,3108,Sulphur_halide,"[#16][F,Cl,Br,I]" +2657,3109,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1 +2658,3110,Pyrylium,c1ccc[o+]c1 +2659,3111,Reactive_carbonyls,"[C;!r](=[O,S])[S;!r]" +2660,3113,Ring_triple_bond,"[C,c;R]#[C,c;R]" +2661,3114,S=N (not_ring),[S;R0]=[N;R0] +2662,3115,Sulfonate_ester,O=[SX4](=O)OC +2663,3116,Sulfonyl_cyanide,S(=O)(=O)C#N +2664,3117,Sulphate_ester,"COS(=O)O[C,c]" +2665,3118,Sulphonates,"COS(=O)(=O)[C,c]" +2666,3119,Sulphur_nitrogen_single_bond,[SX2H0]!@[N] +2667,3120,Tetraazinane,C1NNC=NN1 +2668,3123,Thioles_(not_aromatic),[!a][SX2;H1] +2669,3124,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)" +2670,3126,Three_membered_heterocycle,"*1[O,S]*1" +2671,3127,Tri_pentavalent_S,"[#16v3,#16v5]" +2672,3129,Triazole,c1cnnn1!@C!@[NH1][#6] +2673,3131,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3 +2674,3132,Triphenylphosphines,P(c1aaaaa1)(c1aaaaa1)(c1aaaaa1) +2675,3133,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3) +2676,3134,Vinyl_halide,"[Cl,Br,I]C=[!O!R]" +2677,3135,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)" +2678,3136,Sulphates,[#6]S(=O)(=O)O +2679,3137,Tropone,C1C(=O)C=CC=CC=1 +2680,3138,Oxime,"[#6]C(=!@N[$(OC),$([OH])])[#6]" +2681,3139,Hydrazone,[#6]C(=!@NNa)[#6] +2682,3140,Nitrosone_not_nitro,[$(N(~!@[#6])!@O);!$([N+]([O-])=O)] +2683,3141,Thiocarbonyl_group,C=S +2684,3142,Enamine_like,C=[NH] +2685,3143,Analine,"c1ccccc1[NH2,NH3+]" +2686,3144,Acid_anhydrides_2,"[#6]C(=O)!@OC(=!@[N,O])[#6]" +2687,3145,Trifluroacetate_amide,FC(F)(F)C(=O)N +2688,3146,Triple_bond,[#6]C#[CH] +2689,3148,Thiatetrazolidine,"[$(Sc1nnn[nH,n-]1),$(Sc1nn[nH,n-]n1)]" +2690,3149,Glycol,"[#6][O;R0][$(C([#6])[#6]),$([CH][#6]),$([CH2])][O;R0][#6]" +2691,3150,Oxy-amide,[#6]C(=O)!@C!@C(=O)N +2692,3151,Formate_formide,"O=[CH][O,N][#6]" +2693,3152,Pyranone,O=C1C=COC=C1 +2694,3153,Coumarin,c1cc2C=CC(=O)Oc2cc1 +2695,3154,Aminothiazole,s1ccnc1[N!H0] +2696,3155,Thiazolidinone,O=C1CSCN1 +2697,3156,Thiomorpholinedione,N1C(=O)CSCC1=O +2698,3157,Oxepine,O1C=CC=CC=C1 +2699,3158,Phenylethene,c1ccccc1!@[CH]=!@[C!H0] +2700,3159,Ethene,C=[CH2] +2701,3160,Cyclobutene,C1CC=C1 +2702,3161,Poly_sub_atomatic,*!@c1c(!@*)c(!@*)c(!@*)c(!@*)c1 +2703,3162,Isotopes,"[2#1,3#1,11C,11c,14C,14c,125I,32P,33P,35S]" +2704,3164,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]" +2705,3165,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1] +2706,3166,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-] +2707,3167,Sulphur atom (1),[SX2H1] +2708,3168,Sulphur atom (2),"[$([SX2H0]);!$([S][#6X3,#7X2]);!$([S][CX4H0])]" +2709,3169,Sulphur atom (3),"[$([SX2H0][#6X3,#7X2]);!$([S](~[#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]" +2710,3170,Sulphur atom (4),[$([S][*D4H0]);$([SX2H0])] +2711,3171,Sulphur atom (5),"[$([SX2H0]([#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]" +2712,3172,Sulphur atom (6),[sX2r5] +2713,3173,Sulphur atom (7),[$([#16X3](=[OX1]));$([#16]);!$([#16X3](=[OX1])[#6X3](~[#7X2]))] +2714,3174,Sulphur atom (8),[$([#16X3](=[OX1]));$([#16]);$([#16X3](=[OX1])[#6X3](~[#7X2]))] +2715,3175,Aldehyde carbon atoms,[$([CX3H1](=O)[#6])] +2716,3176,Phosphor with double bonded sulphur,[$([PX4]);$([P]=[S])] +2717,3177,sp3 hybridized carbon atoms (1),[$([CX4]([#6X3])([#6X3])[#6X3]);!$([CH0])] +2718,3178,sp3 hybridized carbon atoms (2),"[$([CX4][N]);!$([CH0]);!$([C][N]([#6X3,#7X2])[#6X3,#7X2]);!$([C][N]=[#6X3]);!$([CX4][NX3][C]=[O])]" +2719,3179,sp3 hybridized carbon atoms (3),"[!$([CH0]);$([CX4]([#6X3])[#6X3]),$([CX4][#7]=[#6X3]),$([CX4]([#8])[#8]);!$([CX4]([#8])[#8][C]=[O])]" +2720,3180,sp3 hybridized carbon atoms (4),[$([CX4][S]);!$([CH0]);!$([C][S]=[O])] +2721,3181,sp3 hybridized carbon atoms (5),"[$([CX4][#6X3]~[#8]),$([CX4][#6X3](~[#7])~[#7]),$([CX4][#6X2]),$([CX4][CX3]=[CX3]-[#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3]);!$([CX4][#6X3](=[#8])-[#8]);!$([CX4][CX3]([CX3])=[CX3]-[#6X3])]" +2722,3182,sp3 hybridized carbon atoms (6),[$([CX4][O]);!$([CH0]);!$([C][O][C]=[O]);!$([CX4]1[O][C]1)] +2723,3183,sp3 hybridized carbon atoms (7),[$([CX4][#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3])] +2724,3184,sp3 hybridized carbon atoms (8),"[$([CX4][#7](~[#6X3,#7X2])~[#6X3,#7X2]);!$([CH0])]" +2725,3185,sp3 hybridized carbon atoms (9),[$([CX4][S](=[O])=[O]);!$([CH0])] +2726,3186,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]" +2727,3187,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])] +2728,3188,sp3 hybridized carbon atoms (12),[$([CX4][NX3H1][C]=[O]);!$([CH0])] +2729,3189,sp2 hybridized carbon atoms (1),"[$([CX3H2]);$([C]=[#6X3,#7X2]-[#6X3,#7X2])]" +2730,3190,sp2 hybridized carbon atoms (2),"[$([CX3H1]);$([C]=[#6X3,#7X2]-[#6X3,#7X2]);!$([C](-[#6X3,#7X2])=[#6X3,#7X2]-[#6X3,#7X2])]" +2731,3191,sp2 hybridized carbon atoms (3),[$([cH1]);$([c](:[#7]):[#7])] +2732,3192,sp2 hybridized carbon atoms (4),"[$([ch1]);!$([ch1]1:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]:[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]1);$([ch1]1:[c](-[NX3]):[c]:[c]:[c]:[c]1),$([c]1:[c]:[c]:[c](-[NX3]):[c]:[c]1)]" +2733,3193,sp2 hybridized carbon atoms (5),"[$([CX3]);$([CX3]=[CX3]);!$([CH0]);!$([CX3](-[#6X3,#7X2])=[CX3]);!$([CX3]=[CX3]-[#6X3,#7X2])]" +2734,3194,sp2 hybridized carbon atoms (6),[$([cH1]);$([c]:[#16])] +2735,3195,sp2 hybridized carbon atoms (7),"[$([ch1]);$([c]1:[c]:[c]:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]1),$([c]1:[c]:[c]:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1)]" +2736,3196,sp2 hybridized carbon atoms (8),"[$([ch1]);!$([c]1:[c]:[c]:[c](-[O]-[C]=[O]):[c]:[c]1);$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1),$([c]1:[c]:[c]:[c](-[O,SX2]):[c]:[c]1)]" +2737,3197,sp2 hybridized carbon atoms (9),[$([cH1]);$([c]1:[c]:[#16]:[c]:[c]1)] +2738,3198,sp2 hybridized carbon atoms (10),"[$([ch1]);$([ch1]1:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]1:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]:[c]-[O,SX2]);!$([ch1]:[c]-[O]-[C]=[O])]" +2739,3199,sp2 hybridized carbon atoms (11),"[$([CX3H1,cX3H1]);!$([ch1]1:[c]:[c]:[#7]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]1);!$([ch1]:[#7])]" +2740,3200,sp2 hybridized carbon atoms (12),"[$([ch1]1:[c]:[c]:[#7]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]1),$([ch1]:[#7])]" +2741,3201,Nitrogen atoms (1),"[$([NX3H0]);!$([NX3][#6X3,#7X2])]" +2742,3202,Nitrogen atoms (2),"[$([NX3]);$([H1,H2])]" +2743,3203,Nitrogen atoms (3),[$([N]([#6X3]1)[#6X3]=[#6X3][#6X4][#6X3]=1)] +2744,3204,Nitrogen atoms (4),"[$([NX3H0]);$([NX3][#6X3,#7X2]);!$([NX3]([#6X3,#7X2])[#6X3,#7X2])]" +2745,3205,Nitrogen atoms (5),"[$([nr6]),$([NX2]=[C])]" +2746,3206,Nitrogen atoms (6),"[$([N]);$([NX3H0]([#6X3,#7X2])[#6X3,#7X2]),$([NX2H1][C]=[O])]" +2747,3207,Nitrogen atoms (7),[nr5H0] +2748,3208,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4 +2749,3209,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6] +2750,3210,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1] +2751,3211,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1] +2752,3212,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3 +2753,3213,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3 +2754,3214,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2 +2755,3215,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8] +2756,3216,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl] +2757,3217,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6] +2758,3218,SA18,c1c(cccc1)-c2ccccc2 +2759,3219,SA19,c1c(cccc1)-c2ccccc2-[Cl] +2760,3220,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1] +2761,3221,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3 +2762,3222,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8] +2763,3223,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8] +2764,3224,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1] +2765,3225,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl] +2766,3226,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl] +2767,3227,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8] +2768,3228,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6] +2769,3229,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6] +2770,3230,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6] +2771,3231,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6] +2772,3232,SA35,c12ccc3c(c1cccc2)cccc3 +2773,3233,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8] +2774,3234,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1 +2775,3235,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6] +2776,3236,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6] +2777,3237,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1] +2778,3238,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2 +2779,3239,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2 +2780,3240,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2 +2781,3241,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br] +2782,3242,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2 +2783,3243,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]" +2784,3244,4-chlorobenzene,Clc1ccc([*:1])cc1 +2785,3245,4-nitrobenzene,[O-][N+](=O)c1cc([*:1])c([*:1])cc1 diff --git a/E_coli activity prediction model/__pycache__/data.cpython-39.pyc b/E_coli activity prediction model/__pycache__/data.cpython-39.pyc new file mode 100644 index 0000000000000000000000000000000000000000..def6c9c806dd9f8a9bd2dcf3bffcecef287d9c86 Binary files /dev/null and b/E_coli activity prediction model/__pycache__/data.cpython-39.pyc differ diff --git a/E_coli activity prediction model/__pycache__/fsr_fg_model.cpython-39.pyc b/E_coli activity prediction model/__pycache__/fsr_fg_model.cpython-39.pyc new file mode 100644 index 0000000000000000000000000000000000000000..5b892fee9c59bd8e067173a240ff24319cd1c967 Binary files /dev/null and b/E_coli activity prediction model/__pycache__/fsr_fg_model.cpython-39.pyc differ diff --git a/E_coli activity prediction model/__pycache__/train_cli.cpython-39.pyc b/E_coli activity prediction model/__pycache__/train_cli.cpython-39.pyc new file mode 100644 index 0000000000000000000000000000000000000000..b1f5460f9a99740d62bee8b23034f3523935eb26 Binary files /dev/null and b/E_coli activity prediction model/__pycache__/train_cli.cpython-39.pyc differ diff --git a/E_coli activity prediction model/codes_drug_chembl_1500.txt b/E_coli activity prediction model/codes_drug_chembl_1500.txt new file mode 100644 index 0000000000000000000000000000000000000000..b586fdbc2fdbb2d4cac4d5fc83de013733f83051 --- /dev/null +++ b/E_coli activity prediction model/codes_drug_chembl_1500.txt @@ -0,0 +1,2657 @@ +#version: 0.2 +c c +C C +O ) +( = +(= O) +cc c +( C +C (=O) +[ C +[C @ +H ] +c 1 +) c +(C ) +c 2 +cc ccc +[C@ @ +[C@ H] +c 3 +[C@@ H] +ccc ( +( CC +N C(=O) +cc ( +C(=O) N +c ( += C +) C +CC CC +) cc +O C +c 4 +C N +C O +F ) +CC N +c1 ccc( +( O) +( F) +)c 3 +2 ) +(=O) N +c n +)c 2 +CC C +(C l +\ C +1 ) +(C) C +S (=O) +3 ) +N ) +)c 4 +[ n +c1 cc +c3 ccccc +O C(=O) +n c( +N C +[n H] +O CC +c 5 +S(=O) (=O) +2 C +cc 1 += O) +ccc( cc +c2 ccccc +c1 ccc ++ ] +)c ( +CCN (CC +n n +[C@H] ( +[C@H] (C +(F) (F) +1 C +2 )c3 +ccccc 4 +) C(=O)N +[C@@H] ( +C l +cc cc +\C =C +c1 ccccc +[C@@H] (C +NC(=O) C +CC (C) +[C@ ] +[ N +) C(=O) +(= C +(Cl )cc +3 C +[ O +[O - +[C@@ ] +[C@H] (CC +=C ( +2 CC +3 )c4 +cc cc( +F )cc +c1 cc( +1 CC +[C@@H] (CC +c2 ccc +[N +] +CCCC C +n 1 +3 CC +)c 5 +n 2 +C(=O) C +c1ccc( cc1 +c (C +c4 ccccc4 +B r +)cc 1 +c2 ccc( +[C@H] (O) += O +c3 ccc +OC(=O) C +) N +CC (=O)N +cc 1) +[C@@H] (O) +n c2 +\C=C \ += N +[O- ] +n cc +CC 1 +[N+] (=O) +c3 ccc( +S(=O) (=O)N +CC (=O) +[C@H] 1 +c3ccccc 3 +N (C +c1ccc( cc1) +c1ccccc 1 +[C@@H] 1 +c1cc cc( +)C (F)(F) +c1ccc 2 +NC(=O) [C@H](CC +N 2 +)c 1 +4 ) +n cn +4 CC +n c3 +c (C) +c 6 +C(=O)N C +(C) CC +ccccc 5 +C c1 +)C 2 +1 )c2 +N =C +S C +CN 1 +c2ccccc 2 +O) cc +ccccc 3 +[C@H] (C) +c [nH] +(= N +CCCC CCCC +n 3 +4 C +[C@H] 2 +CN (C +ccc 1 +(= N) +(C)C ) +OC ) +c2 ccc(cc +CC O +[C@@H] (C) +NC(=O) [C@H](C +cc (C +% 1 +1 =O) +cc 2 +c1ccc (C +=C (C +NC(=O) N +C(=O) O) +(Cl ) +ccc 3 +(Cl )c +Cl . +c2 cc( +c 1 +(C) (C) +\C (=C +2 )C +[C@@H] 2 +CCN (C +N (CC +n c1 +CN C +c4 ccc +ccccc 4 +c2ccccc 2) +ccc 2 +C(=O) O +3 )C +[C@H] 3 +2 =O) +CO c1ccc( +N 1 +CCC (CC +c4 ccc( +CO C(=O) +(=O) O) +CN (CC +c3 ccc(cc +P (=O) +c3ccccc 3) +cc 3 += CC +N 3 +O C +) CC +c( O) +N S(=O)(=O) +CO c1cc( +n 1 +c5 ccccc5 +CO c1cc +c1cccc( c1 +N c2 +)c( OC +5 CC +4 )c5 +c1ccccc 1) +c2ccc 3 +1 =O +c s +c1ccc(cc1 )c2 +o c( +(= S +[C@@H] 3 +C(=O)N [C@@H](CC +c3 cc( +n c4 +# N +c1 n +[O- ] +(O) C +c2 c1 +)cc 1 +N CC +c3 cc +NC(=O) [C@@H]( +)C(F)(F) F +[N+](=O) [O-] +/ C +n 4 +[n +] +CN (C) +ccccc 2 +(C) (C)C +[C@] 1 +2) C(=O)N +CC(C) (C) +n c +ccc 4 +O =C( +2) C(=O) +c2 cccc( +OC O +C c1cc +(=N) N) +F )c +n 2 +5 ) +ccc (Cl)cc +O [C@@H] +# N +N =C( +4 )C +c1 nc( +[N+](=O) [O-] +C(=O)N [C@@H](C +c2 n +)C(=O)N [C@@H](CC +O [C@H](C +c( N +CC (C)C +o ccc +3 =O) +# N) +2)c3 ccccc +(C) C +(C) cc +\C (=N +C (F)(F) +)c 6 +c3ccccc 3 +c2 cccc +\ N=C +CN 2 +CC OC(=O) +c3ccccc 2 +c3 cccc +c2 cc +CNC (=N)N) +O [C@H] +O =C +)c (C +c3 cccc( +P(=O) (O) +ccc( F)cc +( N +c3 c2 +Br )cc +c1 cn +) \ +CO c1ccc(cc1 +O) C +[C@@] 2 +[C@H]( NC(=O) +c 7 +5 C +[C@@H] 1CC +c3ccc 4 +- ] +c2 cn +OC )cc +2 CCN(CC +=N \ +1 =C +nc( N +F )c( +ccccc 5 +S(=O)(=O) C +c3ccc (Cl)cc +CCCC CC +(=O)N C +c4 cc +F )C +C n1 +N (C) +N 4 +3) C(=O) +[C@@] 3 +ccccc 6 +(CC C +1) C(=O) +[C@@] 1 +[C@] 2 +[C@] 3 +c2 c( +\N=C \ +C(=O)N (C +(=S )N +CCN 1 +c4 ccccc4 +c3 n +CO c1ccc2 += CC(=O) +c3 c( +N2 CCN(CC +( O +C c1ccc( +c2ccc (Cl)cc +)C(=O) O +3)c4 ccccc4 +c 2 +OC )c(OC +NC(=O) CC +OC 1 +c2ccc(cc 2) +# C +3CC OCC +OC) c1 +[C@H] 4 +CO c1ccc(cc1) +c4 ccc(cc +n c(C +[O-] [N+](=O) +\C(=C \ +)cc 2 +1 )C +[C@@H] 4 +C(=O) O +c4 ccccc3 +c1 c( +OC(=O)C (F)(F) +ccccc 1 +) NC(=O) +N )C +3 CCCCC +N 2C +OC (C +c1 C +(=O) C +c4 cc( +S CC +3) C(=O)N +F C(F)(F) +c3 cn +2 CCC +\C =N\ +c2ccccc 1 +CO c1ccccc1 +2 =O +C c1cc( +c3ccc( F)cc +[C@@H]( O +\C(=C / +)C(F)(F) F) +[C@@H] 1C +2 =C +F )c3 +CC CN +-] . +n 3 +CO c1ccc(C +c2 c1 +c3ccccc 3C +c1 2 +5 )C +(C)(C) C +c2ccccc 2 +c2cccc( c2 +Br ) +(C)C )C(=O)N +OC(=O)C ) +(C (=O)N +n (C +c (CC +4CC OCC +=C( N) +\C=C / +c4 cccc +[C@H] 1C +)C(=O) C +CC ( +3 CCC +OCC O +c 3 +1) C(=O)N +3)c4 ccccc4 ++] . +S CC(=O)N +3 CCN(CC +c1 ) +)cc 2 +cc (Cl) +n 2) +C(=O)N 1 +[C@@H] 2C +[C@H](O) C +N 2CC +3 CCCC +OCC (=O)N +c1cc 2 +%1 0 +c2ccccc 2C +CCN CC +n 2)c3 +O) [C@@H](O) +. OC(=O)C(F)(F) +O=C( N +CO C(=O)C +CC OC(=O)C +\C=C ( +CCN(CC 1)c2 +)C(=O)N C +O=C 1 +2)c3ccccc 3 +COc1cc 2 +NC 1 +[C@H] 1CC +2 CCCC +[C@] 4 +n1 )c2 +ccc 5 +c4ccccc4 ) +[C@H] 2C +(Cl )c3 +[C@@H] 2CC +[C@@] 4 +% 2 +o nc( +cc (C) +n [nH] +c3ccc(cc 3) +CN 1C +NC(=O) OC +c2ccc( F)cc +c4 cccc( +NC(=O) c2 +)c 2 +)c3 ccccc +(CC (=O)N +3 )cc1 +F )c2 +c6 ccccc6 +\C(=N / +n 5 +[C@@H] 3CC +cc ncc +[N a +2 CCCCC +(Cl )c( +3 =C +2 )c4 +cc 4 +[Na +]. +c( N) +C(=O) OC +NC(=O)[C@H](CC (C)C) +c4 c3 +c2 C +O) c( +N (C)C +NC (=N) +(=S ) +c4ccc (Cl)cc +n c5 +2 (CC +ccc (C +[C@@H](C O) +n ( +cc( OC)c1 +4 CCCCC +O P(=O)(O) +c1cccc(c1 )c2 +CCN C +O =C(C +n c(C) +[ S +N 1C +)c 3 +CC1 (C) +c1 ncn +2 )cc1 +ccc( O)cc +)c (O) +C(=O)N CC +[C@@H](O) C +C c1ccc(cc1) +) S(=O)(=O)N +c4ccc( F)cc +[C@@H] 3C +cc( c1 +c2 c[nH] +6 CC +(C)C )C +=C(N) N) +n 1) +O [C@H]( +c3cccc( c3 +N ( +( [O-] +CC [C@H](C) +CCC (C +c (Cl)cc +3 (CC +.OC(=O)C(F)(F) F +c2 nc( +c1ccccc 1C +cc( O) +NC(=O) NC +c1 nc2 +)c2 c1 +[nH] c( +(C) (C +n cc( +CC (C +)cc 3 +c2 cc1 +C S +c1 c[nH] +) S(=O)(=O) +4 CCCC +c1 nn +[C@@] 5 +O CCN +CCC 1 +2 =N +CC(=O)N C +c1cc cc2 +4 )C(=O) +n 4 +n 3) +c4ccc 5 +2) N +\C(=N \ +)c (C) +F )c4 +c 8 +6 C +5 )c6 +CN1 C(=O) +[C@H] 3CC +CN =C(N)N) +4 =O) +s 1 +CC NC(=O) +c1ccc (Cl)cc +2 / +3 =O +4 )cc1 +s c( +ccc s +\ N=C( +NC(=O)[C@H](CC CNC(=N)N) +6 ) +O[C@H](C O)[C@@H](O) +c2ccc (C +( OC +[N+](=O)[O-] ) +NC 1=O) +NC(=O)[C@H](CC CCN +4 )N += NC +CC n1 +nc( N) +cs c( +[C@H] 3C +2C l +[C@H]( N) +c2cccc 3 +C 1 +CN (C)C +CN ( +[C@@H](C) O) +c4ccccc4 C +n 2C +n2 cn +Cl ) +CN (C)CC +2)c3 ccc( +2) S(=O)(=O) +c 4 +OC )c2 +(Cl )c2 +NC(=O)[C@H](C O) +C NC(=O) +c5 ccccc4 +o c(C +c1ccc(cc1 )C +C(=O) N +O C(=O)N +)C(=O) N +s 2 +CN 3 +c4 cn +(C) (C)C) +2)c3 ccccc3 +Cl c1ccc( +)cc 3 +CCN (C)CC +c2 3 +c2ccc(cc 2 +4) CC +)C(=O)N [C@@H](C +n cccc +N c1nc( +3) CC +[C@H] 5 +c5 ccccc5 +OC )c( +O CCCC +)c2 ccccc +) c1 +O c1ccc( +CO c1ccc(cc1)c2 +c4 c( +)C2 =O) +\C=C( /C +N3 CCN(CC +c1ccc(cc1 )C2 +)c3ccccc 3 +(= CC +)c 7 +c2ccc( O)cc +(C) C(=O) +c %1 +3) N +(F) ( +nn 2 +[C@] (C) +c2 cc3 +O S(=O)(=O) +5CC OCC +[C@@H] 4CC +C(=O)N ) +NC (=S)N +c3 c2 +c5 ccc +(O) (C +NC(=O)C S +n nc( +c3 c[nH] +4 )C(=O)N +OC (F)(F) +c5 ccc( +F c1ccc( +(C )c2 +3 =N +NC(=O) [C@H](C) +) \C +(Cl )c4 +c( cn +C [C@@H]1 +OC [C@H]1 +[C@@H] 5CC +(= NC +O) c2 +C(=O)N (CC +CC(=O) O +CN 1CC +s 3 +4 CCC +S ) +1 )c3 +CCC(CC 1) +c3ccc( O)cc +c3ccccc2 3) +c (Cl) +O) c(O) +C c1ccc(C +[n+] 1 +(=C (C +)c5 ccccc5 +)c4 ccccc4 +)cc1 OC +( N) +\C=C\ C(=O) +ccccc 7 +c3cccc 4 +OCC OCC +N1 C(=O) +\C=C \C +C c1ccc2 +)c 4 +\C=C\ 2/ +s c3 +c3ccc nc3 +2) C(=O)NC +[C@] 5 +% 3 +[C@H] 2CC +c1ccc(cc1) S(=O)(=O)N +\ N +c1cc cc(C +c1 ncc +C c1ccccc1 +O CCC +2)c3 ccc(cc +c1 c2 +C OC +[C@H]( NC(=O)C +CC C(=O)N +(C O +cc 1 +CO c1cccc( +OC)c(OC )c(OC +c1 )c2 +NC(=O)[C@H](CCCCN ) +3 )c1 +N(C) C(=O) +2CC OCC +)C #N +(C )c3 +c2 nn +CC1 =C +2) C(=O)C +)c4 ccccc4 +CCCCCCCC CCCC +COc1cc( cc(OC)c1 +n 1C +1 3 +C S(=O)(=O) +[C@@H] 5 +N2 C(=O) +CCN(CC ) +[C@@H]( NC(=O) +[C@@H]1 O) +[C@H]( OC(=O) +NC(=O)[C@H](CC (=O)O) +(C)C )C(=O)N[C@@H](CC +[C@]4 (C) +(CC CC +(=C ) +s c2 +ccc nc +[C@@] (C) +N(C (=O) +(CC (C +c2ccc nc2 +oc( nn +c2ccccc2 )C +cn cn +ccccc 6 +c2 c(C +CN1 CCN(CC +)c2 cc1 +cc( cn +(Cl)c (Cl)c +5 CCCC +[C@H](O) [C@@H](O) +)C2 =O +( NC(=O) +s c1 +c o +(C O) +(F)( F)C +ncc 3 +1 CCC +(C (=O) +c1ccc(cc1) C(=O)N +NC(=O)[C@H](CC C(=O)O) +[ Br +[Br -]. +OCO c5 +c2ccc(cc 2)C +=C (C) +[C@H](C O) +c4 c3 +cc (CC +c3ccc(cc 3 +cc( OC +c3 C +c3 o +c1ccc 2C +)C(=O) O) +[C@H]( NC(=O)[C@H](C +1 =N +c1ccc( O) +=CC =C +)c5 ccccc5 +[C@@H]( O[C@@H] +CO c1cccc(c1 +5 CCCCC +4CCOCC 4 +O 1 +CO CC +c3ccc(Cl)cc 3 +NS(=O)(=O) C +S SC +4 CCN(CC +NC(=O) [C@@H](C +COc1cc( ccc1 +2 C(=O) +C(=O)N[C@@H](CC CNC(=N)N) +c2ccccc 2)c3 +NC(=O)[C@H](CC (=O)N +cccc 3 +)c 2) +[C@H]( O +N 1CC +NC(=O) c2cc( +c2 ) +c3cc 4 +1C l +c1 c(C) +N 3C +C c1cccc( +3CCOCC 3 +c1ccc2 c( +C ( +O) \ +c3 occc +C(=O)C (=C +[C@@H] (C)CC +C l +C [C@]1 +#N )C +nc( cs +F) cc( +3)c4 ccc( +=C( O +/C / +2 CCC(CC += C +1 )C2 +)C(F)(F) F +NC(=O)[C@@H]( N)C +CN2 C(=O) +O[C@H](CO)[C@@H](O) [C@H](O) +ncn c(N +1 CCN(CC +c3ccc(cc 3)C +N c1n +c2ccccc1 2) +CCN 1C +)c3 ccc( +(O) CC +B r +[C@H] 6 +cccc 2 +c3ccc (C +cn c( +N CCCC +Cl. Cl. +[S +] +O)cc 1 +)c2 C +n o +. OC(=O) +C [C@H]1 +c1ccc( NC(=O) +C (C +nn ( +c2ccc(cc 2)c3 +cc 5 +c3ccccc2 3 +(=O) O +Cc1cc (C) +c2 c(C) +(CC (=O)O) +N CCC +cccc (C +4 =C +ccc (C)cc +ccccc1 4 +CCCCCCCC CCCCCCCC +c3ccc (C)cc +c3ccccc 3)c4 += CC(=O)N +[C@H] 7 +[C@H] 4C +c4cccc( c4 +c5 ccc(cc +c1cc( ccc1 +nc( NC +)cc 2) +2 CCN(C +=C 1 +6 )C +C(=O)N[C@@H](CC CCN +[C@H]( OC(=O)C) +c1ccccc1 )c2 +)C(=O) OC +c1 C +ncc 2 +1) S(=O)(=O) +4 )c3 +(Cl )c1 +s 2) +c3 ncc +c1 3 +CC 1 +c2ccc3 ccccc3 +c5ccccc5 ) +c3ccccc3 )C +c2 nc3 +3 )c( +[C@@]2 (C) +#N )c( +n 5 +3CCCCC 3 +ccc 3C +n 3)c4 +\C=C\ C(=O)N +CCC (C) +1 CCCCC +Cc1 c( +c3ccc( Br)cc +2 C +CN(C) C(=O) +[C@@H] 4C +3) N4 +[C@@H](O) [C@H](O) +\C=C /C +c1ccc(O) cc1) +c4cc 5 +n cc1 +cc( NC(=O) +c1 c(C +3) S(=O)(=O) +=C 3 +cccc( c3 +)cc 4 +OC(F)(F) F)cc +4C ) +n ccc( +c1n nc( +OC ( +5 CCC +C OC1 +c1ccc( O +C [C@H]( +N2 CCC(CC +c1cc (C +nn 3 +[C@@H] (C)C +n2 )C +2) N3 +c2ccc( Br)cc +[C@]3 (C) +c2 o +ccc 2C +c3c[nH] c4ccccc3 +OC(=O) CC +cc 2C +[C@]2 (C) +c5 cc( +C S(=O)(=O)N +=C ) +c2n nc( +4)c5 ccccc5 +c4ccc( O)cc +N=C 1 +cc( ccc2 +2 )c1 +(C)C )N +O [C@@H]( +[Na+]. [Na+]. +CN1 CCN(CC1)c2 +NC(=O)[C@@H]( N) +[C@H] (C)C +(F)(F) F +N2 CCCC +2)c3 cccc +c2ccc (C)cc +O c3ccc( +c1ccccc 1 +\N=C( / +c1ccc( OC +1)c2 ccc( +N c1ncn +NC(=O)[C@H](CC C(=O)N) +OC )C +cc(C (=O)N +[C l +C(=O) OCC +(=O) =O) +[Cl -]. +n (CC +c 9 +O 2 +n ccc +N 3CC +NC(=O)[C@H](CC(=O)N ) +2 =C(C +s 4 +ccccc2 4 +N )c2 +ncn c3 +C(=O) CC +COc1cc (C +oc( cc +n2 c( +4 )cc +4 (CC +2 )c( +c1ccc nc1 +(F)(F) F) +nc 3 +ccc(cc 2 +(=C )C +(Cl )C +N2 CCC +P(=O) ( +C [C@@H]( +=CC(=O) C +s 3) +cc 6 +c2 occc +)C(F)(F) F)cc +CCC NC(=O) +4)c5 ccccc5 +[n+] 2 +c3 c(C) +1) C(=O)C +nc2 c1 +)CC 2 +CCO c1ccc( +c (Cl)c +\C=C(/C )\ +1=C (C) +4 )c1 +c3cc ncc +CC 2 +O[C@H]( [C@H](O) +(O) ( +COc1cc cc(C +4CC 4 += [N+] +c( F)cc +[C@@H] 6 +)c2ccccc 2 +CC(C)C [C@H]( +CC(C)(C) O +c3cccc (Cl)c3 +(C)(C)C )C +nn 1 +=C 2 +C(=O)N CC(=O)N +C [C@@H]1CC +CN 4 +C c1ccc(cc1 +c3 nc( +2) S(=O)(=O)N +c3ccc(F)cc 3 +ccc 1C +[C@@H]1 O +)cc 4 +CC(C) O +OC(=O) C +c2ccc3 OCO +3)c4 ccc(cc +c2n c3ccccc3 +c5 cccc +O) [C@H](O) +CC(C) (C)C +C(=O)N [C@@H](C) +OC )c3 +=CC(=O) O +[C@@]4 (C) +O=C (CC +C ) +CN CC +)CC 1 +n 3C +CC CN(CC +cc cc1 +NC(=O) \C=C\ +O) c3 +nn 2 +O [C@@H]1 +[C@@H] 7 +5 =O) +c2ccc( O +N(C (=O)C +NC(=O) CO +c1 o +[C@]1 2C +[C@]1 (C) +c3ccc4 OCO +4 =O +N=C 2 +c1 )C(=O)N +4CCCCC 4 +([O-] ) +c2ccc(O)cc 2) +[nH] cn +c3ccc( OC)cc +CN1 C(=O)C +NC(=O) CN +c3ccc4 ccccc4 +Cc1cc (C +c2ccc(cc2) S(=O)(=O)N +O [C@H]1 +%1 1 +c3ccc(Cl)cc 3 +c2 s +N (C)C) +CC(=O) O) +N=C( N) +) [N+](=O)[O-] +2)c3 ccc4 +c7 ccccc7 +[ I +c3 c(O) +[C@@H](O) CC +3 CCN(C +c2c[nH] c3ccccc23) +c3ccccc 3)c4ccccc4 +[I -]. += CC(=O)NC +3) C(=O)C +[O-] ) +NC(=O)C 1 +c4ccc (C)cc +(C 2) +c4ccc(cc 4 +COc1ccc(cc1 )C2 +C(F)(F) F +\C(=C ( +1) N +N(CC (=O)N +3 )c5 +1)c2 ccccc +c4ccccc3 4 +c3ccccc 13 +cc nc3 +CCCC 1 +3)c4 cccc +Cc1 cn +C SCC +c5 cccc( +(=N) N +n 4) +[C@H] 4CC +2=O) cc1 +c4cc ncc +nc 2 +)c3 ccc(cc +c4 c[nH] +n 6 +Cl c1ccc(C +)c(OC )c1 +)c3 ccccc3 +[ H] +)c (Cl)c1 +s c4 +N [C@@H](C +CCN(CC )CC +NC(=O) [C@@H](CC +NC(=O)C ) +O c1ccc2 +[C@] 6 +c2cc (C) +(CC (=O) +N3 CCCC +3) C(=O)NC +F c1ccccc1 +[C@@H]4 [C@@]5 +nc1 2 +Cc1 nc( +CC [C@H]1 +2 = +O = +F)c 3 +N2 C(=O)C +F c1ccc(C +c1ccc(Cl)cc 1 +2CC CN(C +O [C@@H]2 +NC(=O)[C@H](C c1ccccc1) +CC 1CC +c3cc (C) +) [N+](=O)[O-] +c1 O +c2ccc( OC +CCCC (=O)N +occc 4 +c2ccc( N +COc1cc cc2 +c5 ccc(F)cc +OCC 1 +O [C@@H](C +=C (C)C +cc( nn +=C( N +c( NC +c2 c(O) +[C@H] 8 +3C l +2)c3 ccc(Cl)cc +N2CCN(CC 2)C(=O) +c2cc ncc +)C 3 +# CC +) n2 +4 )c( +F . +c4ccc nc4 +Cl c1ccccc1 +OCC (=O) +nc2 C +CC(=O) O +[C@@H]( N) +ccc1 2 +c1ccc (C) +co cc +c2ccc( OC)cc +[C@@H]( [C@@H](C)O) +n c5ccccc5 +CC1 =N +3CC 4CC +c2cc( ccc2 +)c4 ccc( +OCC CN +(=O)O) C(=O) +=C(C) C(=O)NC +n c3ccccc3 +Cc1 o +cc(OC)c1 OC +S(=O)(=O) C +n c6 +CCOC(=O)C 1 +F) c1 +c2ccc( NC(=O) +CN3 C(=O) +[C@H](C) O +Br . +C \C(=N/ +N2CC OCC +N(CC C +c2cc (Cl) +OC(=O)C )C +C c1ccc(cc1)c2 +[C@@]2 (CC +3)c4 ccc(F)cc +Cl c1ccc2 +#N )c2 +[C@@H]( OC(=O)C) +c3 nn +(C)C )C(=O) +\N=C / +5 )N +c(N) ncn +)C(=O)N[C@@H](CC CCN +c3 c(C +c1c[nH] c2ccccc12) +NC(=O)C 2 +3) S(=O)(=O)N +[C@H]( N)C +c1 oc( +c5 ccc(Cl)cc +CCCC O +ccccc 8 +1=O) C +2) n3 +c4cccc 5 +c1cc cc +NC(=O) CN2 +c %2 +) C +F c1ccc(cc1) +2CCN(CC 2)c3 +F C +)c 8 +c1cccc(c1 )N +S 1 +)cc 1Cl +% 4 +5CCOCC 5 +CC(=O)N 1 +n2 cc +1 / +c2 ncc +ccc nc3 +O . +Cc1cc 2 +[C@@]3 (C) +COc1ccc2 c( +c3n c4ccccc4 +CC (N +c1ccc( Nc2 +nc 4 +nc( O) +7 ) +)cc 1) +n c1 +\ C(=O)N +C [C@@H](O) +Br )c( +[N -] +F )c5 +CN 2C +ccccc3 4 +CCC ( +CC1 =O) +(CC ) +c4 C +[C@@] (C)(C +Cc1 nn +c4ccccc4 )CC +CN1 C(=O)N(C +COc1ccc(cc1 OC +2)C 3 +(C) cc3 +n1 )C +C(=O)O) C +c1 )C +N2 CCN(C +c1 c(O) +cc( N +c4ccccc4 )C +NC (=S) +Cc1ccc(cc1) S(=O)(=O)N +2CCN(CC 2)C(=O) +COc1ccc(cc1 )C +n2 )cc1 +cc( cc1 +ccc 6 +[nH] 2 +nc2 c1 +3)c4 cccc( +c2ccc(Cl)cc 2) +c3ccccc 3)c4ccccc4 +O=C 1C +OC (C)(C)C +CCN(CC 1)C(=O) +[C@@H]( OC(=O) +c2ccc(cc 2)C(=O)N +)c(C )c1 +c2ccccc 2)c3ccccc3 +C(=O)N[C@@H](CC C(=O)O) +Cc1 onc( +c4ccc(cc 4)C +N 3CCOCC +[C@@H] 5C +( nn +O=C( NC +(=C ( +cc(C) c1 +CN(C (=O) +[C@H](C c1ccccc1) +c3cc (Cl) +)c n1 +CO P(=O)(O) +C [N+] +CCCC CCC +c1 s +c6 ccccc5 +(C) (C)CC +nn c1 +cc( F) +4 )C2 +#N )c3 +NC(=O)[C@H](C c2ccccc2) +c %10 +3 )c2 +c5ccc 6 +[S i +F )c1 +CC(=O) C +(C)C)C(=O)N [C@@H](C +[C@]1 2C +[C@@H]( N)C +CO C(=O)N +cccc( c2 +.OC(=O) C(=O)O +c 5 +n oc( +c3ccc(Cl)cc 3) +CC1 =C(C +n3 )C +CN1 CCC +[C@H]3 O) +c2ccccc2C l +c1n c2ccccc2 +(Cl)c 3 +ccc1 O +OC (C)(C) +3)c4 ccc(Cl)cc +c3 s +[Si ] +1)c2 ccc(cc +c1cn c( +NC(=O)[C@@H]( NC(=O) +2)c3ccccc 3) +C[C@]1 2CC +3CCCCC 3) +c3 cc2 +c4 o +NC 2 +n2cn c3c( +[C@H]1 O +c1 2) +F)c 2 +s 1) +[C@H]( OC +c3ccc(F)cc 3 +[C@H]1CC [C@H]2 +3 CCC(CC +CCO c1ccccc1 +CC1 (C)CC +NC (=N +CCN ( +(=C 1C +c1 [nH] +4 =N +cc( c2 +3CCCC 3 +O c1cc( +n2 nc( +CN(CC (=O)N +c1cccc(c1 )C(=O)N +7 C +(=C 1 +OC 2 +=[N+] = +NCC CN +4 )c2 +C(=O)C (= +NC(=O) N(C +2C 1=O) +CC[C@H](C) [C@H]( +c( OC +cccc 4 +c3ccccc3C 2=O) +NC(=N) N +CC (= +NC 2=O) +O P(=O) +N=C (C +C(=O)N 2 +5 )cc1 +CC S +c2cccc3 ccccc2 +c3ccc (Cl)c +c2ccc3OCO c3c2 +N3 CCCCC +CCN1 C(=O) +NC(=O)[C@H](CC CN=C(N)N) +5 CCN(CC +(C 1) +=CC (=NC +5 )C(=O)N +OC C +)C 1 +CC(C)C [C@H](NC(=O) +CC 2 +n3 cn +\C=N\ NC(=O) +(=N) N +c3 4 +c1ccccc1 )C +(C)(C) [C@@H]5CC +[C@H] 5C +[C@H]( O[C@@H] +(C) cc2 +)c2 ccc( +C(=O)C =C +CCCC (=O) +O=C( N1 +)c4 ccc(cc +n1 c( +4CC 4) +[C@H]2 O) +COc1cc(cc(OC)c1 OC +C(=O)NC (=N +c2ccc(Cl)cc 2 +[C@@] 6 +c4ccc(Cl)cc 4 +P(=O)(O) O) +O= S(=O) +c3ccc(cc 2 +C(=O)N 2C +c2ccc(F)cc 2) +NC (C +(C) O +4CCCC 4 +c1C l +c3ccc(O)cc 3) +c5ccccc5 C +)C(=O)N[C@@H](CC CNC(=N)N) +C [C@@]1 +OC 3 +(Cl)c 2 +nc2 3 +2CCCCC 2) +O c3cc( +3)c4 ccc +2)c3 cc( +CN1 C(=O)N +Nc1ncn c2c1 +Br )c +COc1ccc( OC)c( +[C@H]( N +4 )C(F)(F)F +[C@@]3 4C) +c4ccc(cc 4) +O c4ccccc4 +c3ccc s +COc1ccc(cc1) S(=O)(=O)N +nn [nH] +c1n c(C +c2ccc3 c( +=C(C (=O)N +3C 1=O +c5ccccc4 5 +c3 ncn +=C(C (=O)O)C(=O) +cn 3 +N3 CCC(CC +CO c1ccccc1C +cc(Cl) ccc3 +%1 2 +5 )C(=O) +[C@]3 (C)C +c2cccc (C +O c2ccc( +NC(=O)C ( +O [C@@H](O +Cc1 oc( +)c2cc1 OC +[n+] ([O-] +\ S +O O +c4ccc(F)cc 4 +c3ccc4OCO c4c3 +c3ccc(cc 3)c4ccccc4 +c6 ccccc6 +c1ccc( F)cc +CCCCC 1 +c3 nc4 +F)c 4 +4CC 5CC +6CC OCC +S )N +c4ccc (C +O) c(C +7 CC +c3 ) +[n+] (C +3) n4 +C(=O)N[C@@H](CC CN=C(N)N) +NC(=O)[C@@H]( NC(=O)[C@H](C +CC(C) n1 +COc1cc( OC) +Cc1 nc2 +[C@@H]4[C@@]5 (C)CC +CC(=O)N [C@@H](C +(CC 1 +CCCC N +5CC 5 +[n+] 3 +CC 1C +)C 1=O +)C(F)(F) F)C +c2ccccc2) C(=O)N +CC (O) +[nH] 3 +c1 )c3 +SC ) +c5 c4 +Nc2 ncn +NC(=O)C NC(=O) +c1) S(=O)(=O)N +)C(F)(F) F)c3 +O c1ccccc1 +c3ccccc 1 +CCO C(=O)N1 +OCC CO +N(C) C(=O)N +CC C(=O) +1)c2 ccc3 +[C@]4(C) [C@H]3CC +O NC(=O) +\C(=C /C +c3ccc(F)cc 3) +CO c1cccc(c1)c2 +Cn1 c( +OC 3=O) +O)cc 2 +3C 2=O) +)c3 ) +cn n(C +c2c1 )c3 +[C@@H]1CC CN1C(=O) +)cc2 )cc1 +3 / +n s +CCN (C)C +6 )c7 +n 2CC +CCN 1CC +5 )c4 +S CC(=O) +C(=O)N[C@@H](C O) +c4cccc (Cl)c4 +n 1CC +c4 ncc +N3 CCC +2C l +[C@@H]( O[C@H] +2)c3 ccc(F)cc +n c4ccccc4 +O [C@H]2 +c1ccccc1) C(=O)N +)C2 =N +2 =C( +n2 cc(C +2) C(=O)O +c3occc 3 +(Cl)c 4 +)c4 cccc( +(O)C (O)C +c4ccc(F)cc 4 +cn 2 +n2 nn +c2 cc(C +\N =N\ +O[C@H] (C)C +O) C(=O) +Cl c1ccc(cc1) +c2ccc s +(=O) =O +=C(C (=O) +)cc 3) +CCCC N1 +c3ccc( OC +c2ccc(Cl)cc 2 +CC (CC +CC1 (C)C +c1 C(=O)N +[C@H](C (=O)N +OC(=O) [C@H](C) +[C@@H]( [C@@H](C)CC +NC 3=O) +O[C@H] 1C +C(=O)N[C@@H](CC C(=O)N +O [C@@H]3 +CN4 C(=O) +3 )C(F)(F)F +NC 1=O +CC(=O)N [C@@H](CC +n c3ccccc2 +\ C +ncn 2 +)c (CC +2CC 3CC +[C@]5 (C) +c4ccc( Br)cc +(=C (C) +ccccc1 5 +CO c1c( +c3ccccc3 Cl +F c1cc( +\C(=C \C +(F)(F) F +CCCCCCCC CC +n 4)c5 +O) CC +(CC )C +c4ccc( OC)cc +(Cl )c5 +[C@H](O) CC +N c2cc( +Cl c1cc +S 2 +OC )N +O[C@@H] 1C +c4ccccc3 4) +)C(=O) O +C(=O)O) C(=O)O +n1 )c3 +N4 CCCC +cc nc1 +SC (=S)N +)c 5 +cc1 C +NC1 =N +) O +OCC (O) +N2 CCCCC +Br )c2 +cc( O +CN2 CCN(CC +=[N+]= [N-] +N [C@@H](CC +c2cccc (Cl)c2 +[S+] ([O-] +C(=O)N[C@@H](CC (=O)O) +cc( c3 +c5 ccc(O)cc +3CC CO +2)c3 cn +)c6 ccccc6 +(= CC(=O) +c5 cn +Nc2 nc( +[nH] c2 +6 =O) +=C 1 +\ C(=O) +cn 1) +CO [C@H]1 +N (C)CC +cc( ccc3 +c1 sc( +2)c3 cccc( +\C ) +( [H] +[O-][N+](=O) c1ccc( +N3 C(=O) +c4ccc5 ccccc5 +COC(=O)C 1 +ncc (C +OP(=O)(O) O) +N CCN +ncn c23 +[ P +c2cc1 OC +O) c4 +NC(=O) c2ccccc2 +6 CCCC +c1 )N +CC(=O) OC +nc3 c2 +[C@H](O) [C@H](O) +c4ccc5 OCOc5 +3CC4CC (CC(C +( c4ccccc4 +[C@]2 3 +cc( Br) +CCC 2 +c6 ccc( +[C@H](C c2ccccc2) +c3ccccc3) CC +n (C) +[nH] c3 +c1cc (C) +c3cccc( F)c3 +CCC n1 +.OC(=O)C(F)(F) F +c3ccc(C)cc 3 +c1ccc2 ccccc2 +S \C(=C/ +CN1C(=O)N(C )c2 +C(=O) \C=C\ +c2 3) +OCO c6 +3 )cc1 +(C)C)N (C)C(=O) +NC(=O) \C(=C\ +c4 ccccc2 +CN 2CC +NC(=O) COC(=O) +nn c2 +cccnc 4 +c4ccc(Cl)cc 4 +c3ccc s3 +CN S(=O)(=O) +)C (C)C +1 CCCC +OC 1=O +c4 [nH] +C [C@H](CO) +c2 [nH] +c2ccc( cc1 +(CC CCC +c oc( +)c( N +P(=O)(O) O +(C )c4 +cn c2 +c2c[nH] cn +4)C2 )C +F)c( F)c( +3 )cc2 +OP(=O)(O) OC +C [C@H](CC +OC(=O) \C=C\ +c2c1 )C +O[C@H](C)C [C@@H]( +OC(=O)C(F)(F) F. +S S +Br )cc1 +=C 4 +3)C 4 +(N )C +c(C (=O)N +N(CC CC +\C=C/ 2 +1 =CC +3CC 3 +n 1)C(=O)N +cc1 2 +2) NC(=O) +)c3 c2 +n2cc nc2 +c1ccc2 nc( +c3cc( ccc3 +2) O +c1ccc (Cl)c( +c3 [nH] +c2ccccc2 )cc1 +c(C) cc +N 4CCOCC +CO [C@@H]1 +[C@@H] 8 +F)cc 1 +N1 C(=O)C +[C@] (O)(C +CCN 3 +CCO c1cc( +ccc1 3 +NC(=O)C (C +CO c1ccc2C +CCO c1ccc(cc1) +Br )c3 +c3 cc(C +nc1 C +(=C 2 +CCN 2 +[C@@H]2CC CN2C(=O) +3 =CC +SCC(=O)N C +cc(c1 )c2 +[C@H] 9 +O c3ccccc3 +N 4C +COc1ccccc1 N2CCN(CC +c2ccc3ccccc3 c2 +SSC [C@H]( +NC(=O)[C@H](CCCCN )NC(=O) +[C@H] (C)CC +c4c[nH] c5ccccc4 +6 CCC +CCN(CC )C(=O) +2CCN(CC 2)S(=O)(=O) +c3ccc nc3 +nc3 C +l ) +C [C@@H]1C +C(=O)N )NC(=O) +S(=O)(=O) CC +cc( ccc1 +#N) \ +3)c4 ccc5 +N=C 3 +5 )CC +1CCCCC 1) +[C@H](C) [C@@H](O) +4 )C(=O)C +nn nn +cc nc( +( OC) +C [n+]1 +/C/ 1=C +(C)C )C(=O)N +OC (CC +c3ccc(cc3) S(=O)(=O)N +C [C@H](NC(=O) +c(Cl)cc cc +c3ccc (C)cc3 +n4 cn +c2ccc(Cl)cc 2Cl +5CCCCC 5 +c4 ccccc24 +c2ccccc 2)c3ccccc +2)c3 cccc(c3 +s 1)c2 +c2 c3 +C(=O)N[C@@H](CC (=O)N +%1 3 +c2ccc(F)cc 2 +CCC 2(CC +2CCC [C@H]2 +(=C (N +P(=O) (OC +(F) F) +c1 )C(=O) +c1 onc( +\C=C( / +3)CC 2 +3CC 3) +3=O) C +cc s +NC(=O)C 2CC +)C(=O)N CC +n3 ccnc3 +Cc1cc cc2 +1CC CN(C +onc( n2)c3 +c3cc( OC)c(OC)c(OC +CCN(CC (=O)N +CN(C (=O)C +C(=O)N 1C +O 1) +[C@H](C) [C@@H](O +F c1ccc(cc1)c2 +ccc( N +ccc2 3 +C(=O)NC (C +cc (Cl)c +c8 ccccc8 +cc nc4 +F c1cccc( +2CCCCC 2 +c3ccc(Cl)c (Cl)c3 +nc( n1) +3) C(=O)O +c2cc( ccc1 +P (=S) +)c3 C +c2ccccc1 2 +c2ccccc2C 1=O) +cc1 )c2 +c2cc(Cl) ccc2 +5 )cc +c%1 1 +O[C@H]([C@H](O) [C@@H]1O) +CC1 =CC +ccccc4 5 +C(=O)C =C(O +[C@@H]2 O) +CC[C@H]1 OC(=O)[C@H](C) +nn 3 +[C@]2 3C +\C =N +c3o ccc3 +c1 occc +)C #N) +(C)C )c2 +cccs 4 +3 =C(C +4C l +[C@H]1 O) +CCN S(=O)(=O) +c2cccc(c2 )c3 +ccc nc2 +cc(Cl) c1 +CN(C) S(=O)(=O) +c3cc( ccc2 +c4cc5 OCOc5 +COc1ccc(cc1 OC)c2 +)c (Cl)cc +(=O) OC +[C@@H](O) [C@@H](O) +cc( [nH] +CCN (C) +3CC4CC(CC(C 4)C2)C +nn 1 +S(=O)(=O) N +OC 2=O) +NCC (O) +2) \ +c5 c[nH] +) n1 +NC(=O) c1cc( +N4 CCN(CC +e ] +OCC (=O)NC +N1C [C@H](C) +CCC [C@H]1 +[C@H]3 [C@@H](CC +CC(C) N1 +CC [C@@]1 +NC(=O) c2cn +N(C (C +Cl c1ccc(cc1)c2 +[C@@H]( OC +3CCC [C@H]3 +NC(=O)[C@H](C c2ccc(O)cc2) +C(=O)N [C@H](C +CC(C) [C@H](NC(=O) +CC(C) (C +c3c( F)cc +ncccc 3 +Cc1 n +N4 CCCCC +Cc1cc(C )c( +c5 ccccc3 +4)C #N +c4ccccc4 )c5 +cn c(N +c1 OC +ccncc 4 +NC(=O) c2ccc( +c2ccc (Cl)c(Cl)c +\N=C( /C +c3cc(Cl) ccc3 +5 C(=O) +N) N +c2 oc(cc +O)cc 3 +6 CCCCC +n 4C +c4ccc s +nc (CC +3CCN(CC 3)C(=O) +c2ccc (Cl)c +( NC(=O)C +n2 C +SC 1 +CC NC(=O)N +NC(=O)OC (C)(C)C +N 4CC +[C@](C) (O) +CC (O +ncccc 4 +cccnc 3 +)c4 ) +NC(=O) C +8 C +( S +1CC OCC +c(C )c(C +OC(=O)C 1 +)C(F)(F) F)c4 +CC c1ccc( +c %3 +4 )C(=O)O +(=S )NC(=O) +[C@H]3 O +NC(=O) c1cn +CN(CC O +Cc1cc cc(C)c1 +)c3 c2 +(O) (CC +[C@] (C)(C +F)cc 3 +OCC (=O)O) +c3ccccc3 )c( +ncc 4 +[C@]12C ) +c2 4 +c3cccc4 ccccc3 +ccc( OC)cc +O[C@@H] 4 +C [C@H]1C +O [C@@H](C) +F c1ccc2 +O=C( NCC +CN(C) c1ccc( +CN1 CCN(C +c3ccc(cc 3)c4 +c2 oc(nn +\C=C\ 3/ +c2c1 ) +[nH] 4 +NS(=O)(=O) c1ccc( +)c6 ccccc6 +c1ccc(cc1)C2 =N +nc( n2) +(O) C(=O) +N c1cc( +CC[C@H](C) [C@@H]1 +( N1 +ccc 7 +C(=O)N[C@@H](C c2ccccc2) +3CCCCC 3 +c2 ncn +CC(= CCC +c1ccc 2CC +COP(=O)(O) O[C@H] +c3c( [nH] +c2 oc( +[C@H]( OC) +COc1ccc( CC +Cc1cc cc(C +8 ) +# C +(CC =C +\N=C\ 2/ +FC (F)(F)C +Cl c1cccc( +5CCCC 5 +)c 9 +( NC +c4 nc5ccccc5 +O c1c( +)C 1 +[nH] 1 +NC(=O)C SC +[C@H] 5CC +C [C@@H](CO) +1)c2ccccc 2 +c4 ) +)C(F)(F)F )C(F)(F)F +c4 s +NC(=O)c2 cc3 +n2 )c1 +cccs 3 +c( nn +[C@H](CC (=O)N +[C@@]2 3 +ccc (Cl)c(Cl)c +Cc1ccc(C )c( +CCn1 c( +3CCOCC 3) +O) C(=O)N +cc(Cl) ccc2 +NC(=O)C =C +(CC (=O)NC +2 )cc1 +ccc 4C +cc(cn 1)c2 +N2CCN(CC 2)c3 +c1 4 +Cc1o nc(C) +OC (C)C +CC(C)C [C@@H]1 +N 1 +c(C )c +P(=O)( OCC +C [C@H](C +(C)(C)[C@@H]5CC [C@@]34C) +F)c 2) +(= CC(=O)O +c1 csc( +N(C) S(=O)(=O) +c2cc( O) +c1ccccc1) C(=O) +S1 (=O)=O) +7 )C +c3cccc n3 +(C) C(=O)N +C(F)(F) F) +C (N +cc(C (=O) +cc nc(N +c1ccc(cc1 Cl +[C@H](C c3ccccc3) +nc (Cl) +c2ccc(cc 2)c3ccccc3 +c4 occc4 +[C@H](CC (C)C) +N [C@H](C +3 = +CCC S +3)C #N +c(C) c1 +[C@@] 7 +\C(=C/ 1 +\N=C\ 1/ +([H] ) +c3 c4 +=CC =CC +ccc nc4 +CO CCN1 +nc(C (=O)N +c1ccc(C) cc1 +[C@@H]3 O[C@H](C +\C(=N/ O)\ +1) \ +[nH] nc( +O c5 +F)cc 1 +4 )cc3 +2 3 +c(C )c( +c4cc( O) +CC S(=O)(=O)N +ccccc 7 +\C(=C\ CC +OC )C(=O) +)C(=O)N[C@@H](CC (=O)N +c4 ccccc14 +ccc(F)cc 5 +[C@@H]3CC CN3C(=O) +c1ncc cc1 +cc( OC) +( c3ccccc3)c4ccccc4 +c3ccccc3 )c2 +C(=O)N 1CC +n3 cncn +c(O) c( +)C(F)(F) F)c2 +(Cl) ccc1 +c2ccc(F)cc 2 +nc1 3 +2CC CO +c3ccccc3 C(=O) +c2ccccc2) C(=O) +[C@H](CC CCN +c4 cc3 +)c4 cccc +)C (C)(C) +CCCC (C) +c1ccccc 1CC +nn n[nH] +cc1 OC +cc [nH] +[C@@]3 4C +c2ccccc1 2)C(=O)N +)c4 ccc(Cl)cc +c3ccccc3) C(=O) +CCC(CC 1)c2 +5 (CC +[C@@H]1CC [C@H](CC +=CC (= +[C@H]2 [C@@H]3 +[C@@]1 (C) +COc1ccc( NC(=O) +c3cc( O) +c6ccccc6 ) +c2nc( cs +c2ccc s2) +S(=O)(=O)N C +O=C( NC1 +3) [N+](=O)[O-] +.OC(=O)C(F)(F)F .OC(=O)C(F)(F)F +CC [C@@H](C) +c3ccc( N +CC OCC +O)[C@H](O) [C@H](O) +2)c4 ccccc4 +CO CCO +N =N +CC 3 +nc( NCC +NC(=O)[C@@H](N) CC +5 )c( +B (O) +cn cc +O c1ccc(C +O 3 +NC(=O)C 2=C +COc1ccc(cc1) C(=O)N +c1ccc2c( c1) +2C (C +CC(C)(C) OC(=O)N +\C(=N\ O)\ +O c1ccc(cc1)c2 +nc( NC(=O) +c2C 1=O) +F) ccc1 +CCN1 CCN(CC +4 )C2=O +CCCC CCCCC +c2ccc( F)c( +(C)C )C(=O)O +3) O +2)N 3C +2 =NC +N(C 1=O) +)c4 ccc(F)cc +c3ccccc3 )cc1 +CCCN(CC C +c2cccc(c2 )S(=O)(=O)N +ccccc1 3 +n4 )C +)C(=O) C +5 CCNCC +) n2 +c6 ccc(cc +O [C@H]3 +CN1 CCC(CC1) +CC(C) [C@H]( +3 CCCCCC +cc( o +c3cccc (C +CCN(C (=O) +CC1 (CC +CO c1n +c3cccc (C)c3 +c2ccc(cc 2C +CN c1nc( +)C 1=O) +(F) F +n 5) +N) \ +2)c3ccc(Cl)cc 3 +c1ccc (Cl)c +[C@@]3 4 +O c2ccccc2 +)cc1 2 +c3ccccc3C l +cc(Cl) ccc4 +(C)C) C +NC(=O)[C@H](C c3ccccc3) +4 )c +CC(C) (O) +4CC5CC (CC(C +c3 cs +CC(=O) N +CO c1ccc(Cl)cc1 +1=C N(C +) ccc1 +nc( [nH] +1) C(=O)O +[C@@] (O)(C +)c( c2 +NC(=O)C )C +c3ccccc3 c2 +c5 ccncc +CC1=C N( +3(CC 2) +c4cccc( F)c4 +[C@]3 (C)CC +N1C [C@@H](C) +O c1ccc(cc1) +1CCN(CC 1)C(=O) +n2 3 +ccc(Cl)cc 3 +CO C(=O)N1 +CCCC (C +c3cccc n3) +Cn1 cc( +c5 c4 +[N+](=O)[O-] )cc1 +N=C( S)N +\C=C \C=C\ +N (C)C +2)C(=O)NC 1=O +NC(=O) c3cc( +[C@@]4 (C)CC +CC OC +c1C #N +CN(CC C +4CC5CC(CC(C 5)C +S2 (=O)=O) +O c2cc( +1 = +c1ccccc1 )c2ccccc +CC( NC(=O) +[C@@H](O) [C@@H](O[C@@H] +c2ccc3 OCCO +(=O)N (C +ccccc2 3 +C(=O)N CCC +OCC =C +)C(=O)N [C@@H](C) +c(Cl)cc (Cl)cc +)c2 3 +2 (C +OS(=O)(=O) O) +NC(=O)N CC +C(=O)N 2CC +c4cc (Cl) +)C(=O)N [C@@H](CO) +c1ccc( N +[C@@]3 (C +C(=O)N[C@@H](C (C)C)C(=O)N +4 CCC(CC +3 CCNCC +(C c2ccccc2) +n 2)C(=O)N +c5ccc(cc 5 +c5cccc( c5 +c3c[nH]c4ccccc3 4) +OC(=O) [C@H](C +3 =C( +C c1cccc(c1 +5 =O +2) [N+](=O)[O-] +c1cccc2 ccccc1 +C(=O) OC +2CC (=N +c3ccccc3C 2=O +CC S(=O)(=O) +O[C@H] 4 +=C 1) +cc (Cl)cc +CN 3C +[C@@H](CC C +c3ccc s3) +c2ccc( NC(=O)C +c3occc 3) +c2ccc nc2 +c%1 2 +c2ccccc 2)c3ccccc3 +4)CC 2 +cn c3 +)C (C)(C)C +n c2ccccc1 +)c2C 1=O +c3c(F)cc cc3 +c4ccc nc4 +nn (C +Cc1 c(C +c2ccc (C)cc2 +3CCN(CC 3)c4 +CC (=C) +c2c(C 1) +ccc(cc 3 +Cc1ccc(cc1) S(=O)(=O) +c3ccc4ccccc4 c3 +CCC 4 +CN2 CCC +1CCC [C@H]1 +cc( OC)c(OC +CCN(CC )C +c2ccc s2 +c2ccccc2 )c( +[C@@H]4CC CN4C(=O) +[C@@H](C O +4)CC 1 +cn 1)c2 +c3ccc( O +)C #N +OC[C@H]1 O[C@H]( +c4ccccc4 c3 +c1cc( cc(c1 +C(=O)N (C)C +c1nn ( +=C(C (=O)NC +O)c( OC +CCOC(=O)C 1=C(C) +n1 C +c3n cc( +c3ccc(cc 3)C(=O)N +c1 oc(C +N )c3 +2) n1 +c( O +[C@H](CC CNC(=N)N) +3)c4ccc(Cl)cc 4 +CN(C (=O)O +CC1 =C( +c6 ccc(O)cc +CCO c1ccc(C +I ) +c3 C(=O) +c2c1 )N +nc( nc3 +NC(=O) CCC +9 C +NC(=O) O +CC[C@H](C) [C@H](NC(=O) +[C@H](NC(=O)[C@H](C c1ccccc1) +c3ccc( F)c( +\N=C( \ +3CCC (C +F) ccc2 +C[C@]12CC [C@H]3[C@@H](CC +4)c5 cccc +CCCC N1C(=O) +CC c1cc( +)c(C) c1 +c1c[nH] cn1) +1 CCN(CC1)c2 +cn [nH] +CC(=O)N 1CC +n1 )C2 +CC CO +c1ccc( NC(=O)N +cc 3C +nc 5 +c3ccc( NC(=O) +(C)(C) O +4 )cc2 +(F)(F)C (F)(F)C +[C@H]( N(C +CN =C( +C (CC +5 )c1 +c1ccc2 OCO +[C@H]2 O +C = +c2ccc (Cl)c( +CC1 CCN(CC +4CCOCC 4) +n2 cc( +5 )c3 +2 )c5 +[n+] (CC +NC(=O) c2ccc3 +CC1(C) CCC +ccc( Br)cc +S(=O)(=O) O) +n2 ccc3 +Cc1cc( ccc1 +N(C) C(=O)C +CC1 =O +3 (C +1) O +5 CCN(C)CC +(CC 2=O) +nc( nc1 +c2c( [nH] +c1 2)c3 +2 CO +OC(C O)C +( OC(=O) +c4 c(C) +Br) cc( +[C@]6 (C) +Nc2 nc(N +)C 4 +c3ccc(O)cc 3 +NC1 = +c2ccc 3C +(C)C )c3 +ccc 2Cl +O=C1 N +3)c4ccc(F)cc 4 +(C)(C) O) +CC [C@@H]1 +c4 c(O) +c1 2)C +C(=O)O . +[C@H]( O[C@H] +OCCOCC OCCOCC +)cc 2C +c4ccc(O)cc 4) +ccc(F)cc 3 +4)c5 ccc(cc +[C@@](C) (O) +c3ccncc 3 +[C@](C) (O)C +O=C(C S +c2cc( OC)c(OC)c(OC +c4 c5 +o nc2 +3)CC 1 +CCCCCCCC CCCCCC +( NC(=O)N +s c2c1 +\C 1=O +COc1cc(OC) cc(c1 +[ 1 +OC(=O) c1cc( +)C2=O) cc1 +)C(=O)N[C@@H](CC (C)C)C(=O)N[C@@H](CC +( N(C +OC 4 +c4 c(C +nn c3 +[S e] +P(=O)( S) +)cc1 O +ncn c2 +nn 4 +C(=O)N[C@@H](CCCNC(=N)N) C(=O)N[C@@H](CCCNC(=N)N) +ccncc 3 +c4ccc(Cl)cc 4) +[C@H]( NC +O c1ccc(cc1 +CCN(C 1)c2 +2 C(=O)N +c1) [N+](=O)[O-] +c4o ccc4 +N1 CCCC +OC(=O)C (=C +c2ccc(C)cc 2 +CC1 CN(CC +OC (=CC(=O) +O=C 1CC +3)C(=O) N +c2 )C(=O)N +3)C 2 +\C=C/C \C=C/C +CC1 )c2 +occc 3 +NC1=O) C +c3ccc( OC)c(OC +[C@H]( OC(=O)C +=C (C)C) +c4cc (C) +)C(=O)N[C@@H](CC C(=O)O) +Cl) CCC +ccc (Cl)c +Nc2 nccc( +(Cl)c 2) +ccccc 2 +4CC CO +nc3 c( +c3cc nc4 +c2c( F)cc +2CCC (C +c2 cs +NC(=O) CCCC +(O) CO +%1 4 +CC c1ccccc1 +OC(=O) c1ccccc1 +1=C (O) +O[C@@H] 5 +nc( nc2 +S(=O)(=O)C ) +N4 CCC +4CCCCC 4) +5)C #N +)N (C +NC(=O)[C@H](CC C(=O)N)NC(=O) +[C@]2 (C +c (Cl)c( +c4ccc(F)cc 4) +)N 2C +C(=O)N CCCC +NC(=N) NCCC +2=C 1C +ccc(Cl)cc 5 +)c(O) c1 diff --git a/E_coli activity prediction model/data.py b/E_coli activity prediction model/data.py new file mode 100644 index 0000000000000000000000000000000000000000..1f74bd00451dbc0346f560c857dd9362fe80d111 --- /dev/null +++ b/E_coli activity prediction model/data.py @@ -0,0 +1,155 @@ +from rdkit import Chem +import codecs +import numpy as np +import pandas as pd +from rdkit.Chem import Descriptors +from subword_nmt.apply_bpe import BPE +import deepchem as dc +import deepchem.molnet as dcm +from rdkit import RDLogger +from torch.utils.data import DataLoader, Dataset, Subset +from pytorch_lightning import LightningDataModule + + +lg = RDLogger.logger() +lg.setLevel(RDLogger.CRITICAL) + + +def smiles2index(s1, words2idx, bpe): + t1 = bpe.process_line(s1).split() + i1 = [words2idx[i] for i in t1] + return i1 + + +def index2multi_hot(i1, idx2word): + v1 = np.zeros(len(idx2word)) + v1[i1] = 1 + return v1 + + +def index2multi_hot_fg(molecule, fgroups_list): + v1 = np.zeros(len(fgroups_list)) + for idx in range(len(fgroups_list)): + if molecule.HasSubstructMatch(fgroups_list[idx]): + v1[idx] = 1 + return v1 + + +def smiles2vector_fgr(s1, words2idx, bpe, idx2word, fgroups_list): + i1 = smiles2index(s1, words2idx, bpe) + mfg = index2multi_hot(i1, idx2word) + molecule = Chem.MolFromSmiles(s1) + fg = index2multi_hot_fg(molecule, fgroups_list) + return fg, mfg + + +class FsrFgDataset(Dataset): + + def __init__(self, data, idx2word, fgroups_list, words2idx, bpe, descriptor_funcs): + self.mols = data.X + self.y = data.y + self.smiles = data.ids + self.idx2word = idx2word + self.fgroups_list = fgroups_list + self.words2idx = words2idx + self.bpe = bpe + self.descriptor_funcs = descriptor_funcs + + def __len__(self): + return len(self.y) + + def __getitem__(self, idx): + mol = self.mols[idx] + smile = self.smiles[idx] + target = self.y[idx] + + fg, mfg = smiles2vector_fgr(smile, self.words2idx, self.bpe, self.idx2word, self.fgroups_list) + num_features = np.asarray([self.descriptor_funcs[key](mol) for key in self.descriptor_funcs.keys()]) + return np.float32(fg), np.float32(mfg), np.float32(num_features), int(target) + + +class FsrFgDataModule(LightningDataModule): + def __init__(self, root: str = 'Data', task_name: str = 'ecoli', batch_size: int = 8, num_workers: int = 8, + pin_memory: bool = True, split_type: str = 'scaffold', num_folds: int = 5, fold_index: int = 0): + super().__init__() + + self.root = root + self.task_name = task_name + self.num_workers = num_workers + self.pin_memory = pin_memory + self.batch_size = batch_size + self.split_type = split_type + self.num_folds = num_folds + self.fold_index = fold_index + self.test_fold = None + self.val_fold = None + self.train_fold = None + self.fgroups_list = None + self.descriptor_funcs = None + self.bpe = None + self.idx2word = None + self.words2idx = None + self.val_data = None + self.test_data = None + self.train_data = None + self.splits = None + + def prepare_data(self) -> None: + df = pd.read_csv('Data/ecoli_inhibition.csv') + ids = df['smiles'] + labels = df['Encoded_Activity'] + X = [Chem.MolFromSmiles(smiles) for smiles in ids] + data = dc.data.DiskDataset.from_numpy(X=X, y=labels, ids=ids) + fgroups = pd.read_csv(self.root + '/Functional_groups_filtered.csv') + fgroups_list = list(map(lambda x: Chem.MolFromSmarts(x), fgroups['SMARTS'].tolist())) + self.fgroups_list = [i for i in fgroups_list if i] + + self.descriptor_funcs = {name: func for name, func in Descriptors.descList} + + vocab_path = self.root + '/codes_drug_chembl_1500.txt' + bpe_codes_fin = codecs.open(vocab_path) + self.bpe = BPE(bpe_codes_fin, merges=-1, separator='') + vocab_map = pd.read_csv(self.root + '/subword_units_map_drug_chembl_1500.csv') + self.idx2word = vocab_map['index'].values + self.words2idx = dict(zip(self.idx2word, range(0, len(self.idx2word)))) + self.weights = data.w + if self.split_type == 'scaffold': + splitter = dc.splits.ScaffoldSplitter() + self.splits = [] + for i in range(self.num_folds): + new_data = data.complete_shuffle() + self.splits.append((new_data, splitter.split(dataset=new_data, seed=i))) + self.dataset = FsrFgDataset(self.splits[self.fold_index][0], self.idx2word, self.fgroups_list, self.words2idx, self.bpe, + self.descriptor_funcs) + self.train_ind, self.val_ind, self.test_ind = self.splits[self.fold_index][1] + else: + splitter = dc.splits.RandomStratifiedSplitter() + self.splits = [splitter.split(dataset=data, seed=fold_num) for fold_num in range(self.num_folds)] + self.dataset = FsrFgDataset(data, self.idx2word, self.fgroups_list, self.words2idx, self.bpe, + self.descriptor_funcs) + self.train_ind, self.val_ind, self.test_ind = self.splits[self.fold_index] + + def setup(self, stage=None): + """define train, test and validation datasets """ + + self.train_fold = Subset(self.dataset, self.train_ind) + self.val_fold = Subset(self.dataset, self.val_ind) + self.test_fold = Subset(self.dataset, self.test_ind) + + def train_dataloader(self): + """returns train dataloader""" + loader = DataLoader(self.train_fold, batch_size=self.batch_size, shuffle=False, + num_workers=self.num_workers, pin_memory=self.pin_memory, drop_last=True) + return loader + + def val_dataloader(self): + """returns val dataloader""" + loader = DataLoader(self.val_fold, batch_size=1, shuffle=False, + num_workers=self.num_workers, pin_memory=self.pin_memory) + return loader + + def test_dataloader(self): + """returns test dataloader""" + loader = DataLoader(self.test_fold, batch_size=1, shuffle=False, + num_workers=self.num_workers, pin_memory=self.pin_memory) + return loader diff --git a/E_coli activity prediction model/epoch=22-step=5359.ckpt b/E_coli activity prediction model/epoch=22-step=5359.ckpt new file mode 100644 index 0000000000000000000000000000000000000000..651d78cfbf312b1512e159e584677d6a3f98a4ce --- /dev/null +++ b/E_coli activity prediction model/epoch=22-step=5359.ckpt @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:1af00203a915145f052987fa39eaa8b7bf4d826d30507fa55ec47cd3b64fa96f +size 66337521 diff --git a/E_coli activity prediction model/fsr_fg_model.py b/E_coli activity prediction model/fsr_fg_model.py new file mode 100644 index 0000000000000000000000000000000000000000..c5097ef329c6304b7eeaf8afbb5772aeb3f4767c --- /dev/null +++ b/E_coli activity prediction model/fsr_fg_model.py @@ -0,0 +1,75 @@ +import torch +from torch import nn + + +def make_encoder(input_dim, enc_dec_dims): + encoder_layers = [] + decoder_layers = [] + output_dim = input_dim + enc_shape = enc_dec_dims[-1] + for enc_dim in enc_dec_dims[:-1]: + encoder_layers.extend([nn.Linear(input_dim, enc_dim), nn.SELU()]) + input_dim = enc_dim + + encoder_layers.append(nn.Linear(input_dim, enc_shape)) + + enc_dec_dims = list(reversed(enc_dec_dims)) + for dec_dim in enc_dec_dims[1:]: + decoder_layers.extend([nn.Linear(enc_shape, dec_dim), nn.SELU()]) + enc_shape = dec_dim + + decoder_layers.append(nn.Linear(enc_shape, output_dim)) + + return nn.Sequential(*encoder_layers), nn.Sequential(*decoder_layers) + + +class FsrFgModel(nn.Module): + def __init__(self, fg_input_dim, mfg_input_dim, num_input_dim, enc_dec_dims, output_dims, + num_tasks, dropout, method): + super(FsrFgModel, self).__init__() + + self.method = method + if self.method == 'FG': + input_dim = fg_input_dim + elif self.method == 'MFG': + input_dim = mfg_input_dim + elif self.method == 'FGR': + input_dim = fg_input_dim + mfg_input_dim + else: + input_dim = fg_input_dim + mfg_input_dim + if self.method != 'FGR_desc': + fcn_input_dim = enc_dec_dims[-1] + else: + fcn_input_dim = num_input_dim + enc_dec_dims[-1] + self.encoder, self.decoder = make_encoder(input_dim, enc_dec_dims) + self.dropout = nn.Dropout(dropout) + self.predict_out_dim = num_tasks + self.batch_norm = nn.BatchNorm1d(fcn_input_dim) + + layers = [] + for output_dim in output_dims: + layers.extend([nn.Linear(fcn_input_dim, output_dim), nn.SELU(), nn.BatchNorm1d(output_dim)]) + fcn_input_dim = output_dim + + layers.extend([self.dropout, nn.Linear(fcn_input_dim, num_tasks)]) + + self.predictor = nn.Sequential(*layers) + + def forward(self, fg=None, mfg=None, num_features=None): + + if self.method == 'FG': + z_d = self.encoder(fg) + elif self.method == 'MFG': + z_d = self.encoder(mfg) + elif self.method == 'FGR': + z_d = self.encoder(torch.cat([fg, mfg], dim=1)) + else: + z_d = self.encoder(torch.cat([fg, mfg], dim=1)) + + v_d_hat = self.decoder(z_d) + + if self.method == 'FGR_desc': + z_d = torch.cat([z_d, num_features], dim=1) + + output = self.predictor(z_d) + return output, v_d_hat diff --git a/E_coli activity prediction model/subword_units_map_drug_chembl_1500.csv b/E_coli activity prediction model/subword_units_map_drug_chembl_1500.csv new file mode 100644 index 0000000000000000000000000000000000000000..c19ae21edecc044694ed634ee7678de191b40666 --- /dev/null +++ b/E_coli activity prediction 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satisfied: Pillow in c:\\users\\prajwal\\appdata\\local\\programs\\python\\python39\\lib\\site-packages (from rdkit) (9.2.0)\n", + "Requirement already satisfied: numpy in c:\\users\\prajwal\\appdata\\local\\programs\\python\\python39\\lib\\site-packages (from rdkit) (1.23.3)\n", + "Note: you may need to restart the kernel to use updated packages.\n" + ] + } + ], + "source": [ + "pip install rdkit" + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Requirement already satisfied: torch in c:\\users\\prajwal\\appdata\\local\\programs\\python\\python39\\lib\\site-packages (1.13.1)\n", + "Requirement already satisfied: typing-extensions in c:\\users\\prajwal\\appdata\\local\\programs\\python\\python39\\lib\\site-packages (from torch) (4.3.0)\n", + "Note: you may need to restart the kernel to use updated packages.\n" + ] + } + ], + "source": [ + "pip install torch" + ] + }, + { + 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+ "output_type": "stream", + "text": [ + "Could not fetch URL https://pypi.org/simple/deepchem/: There was a problem confirming the ssl certificate: HTTPSConnectionPool(host='pypi.org', port=443): Max retries exceeded with url: /simple/deepchem/ (Caused by SSLError(\"Can't connect to HTTPS URL because the SSL module is not available.\")) - skipping\n", + "Could not fetch URL https://pypi.org/simple/pip/: There was a problem confirming the ssl certificate: HTTPSConnectionPool(host='pypi.org', port=443): Max retries exceeded with url: /simple/pip/ (Caused by SSLError(\"Can't connect to HTTPS URL because the SSL module is not available.\")) - skipping\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + "WARNING: pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.\n", + "WARNING: Retrying (Retry(total=4, connect=None, read=None, redirect=None, status=None)) after connection broken by 'SSLError(\"Can't connect to HTTPS URL because the SSL module is not available.\")': /simple/deepchem/\n", + "WARNING: Retrying (Retry(total=3, connect=None, read=None, redirect=None, status=None)) after connection broken by 'SSLError(\"Can't connect to HTTPS URL because the SSL module is not available.\")': /simple/deepchem/\n", + "WARNING: Retrying (Retry(total=2, connect=None, read=None, redirect=None, status=None)) after connection broken by 'SSLError(\"Can't connect to HTTPS URL because the SSL module is not available.\")': /simple/deepchem/\n", + "WARNING: Retrying (Retry(total=1, connect=None, read=None, redirect=None, status=None)) after connection broken by 'SSLError(\"Can't connect to HTTPS URL because the SSL module is not available.\")': /simple/deepchem/\n", + "WARNING: Retrying (Retry(total=0, connect=None, read=None, redirect=None, status=None)) after connection broken by 'SSLError(\"Can't connect to HTTPS URL because the SSL module is not available.\")': /simple/deepchem/\n", + "ERROR: Could not find a version that satisfies the requirement deepchem\n", + "ERROR: No matching distribution found for deepchem\n", + "WARNING: pip is configured with locations that require TLS/SSL, however the ssl module in Python is not available.\n" + ] + } + ], + "source": [ + "!pip install deepchem" + ] + }, + { + "cell_type": "code", + "execution_count": 7, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Requirement already satisfied: pip in c:\\users\\prajwal\\appdata\\local\\programs\\python\\python39\\lib\\site-packages (23.0.1)\n", + "Note: you may need to restart the kernel to use updated packages.\n" + ] + } + ], + "source": [ + "pip install --upgrade pip" + ] + }, + { + "cell_type": "code", + "execution_count": 8, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Requirement already satisfied: deepchem in c:\\users\\prajwal\\appdata\\roaming\\python\\python39\\site-packages (2.6.1)\n", + 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"execution_count": 9, + "metadata": { + "collapsed": false + }, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "c:\\Users\\Prajwal\\AppData\\Local\\Programs\\Python\\Python39\\lib\\site-packages\\tqdm\\auto.py:22: TqdmWarning: IProgress not found. Please update jupyter and ipywidgets. See https://ipywidgets.readthedocs.io/en/stable/user_install.html\n", + " from .autonotebook import tqdm as notebook_tqdm\n" + ] + } + ], + "source": [ + "from train_cli import FsrFgLightning\n", + "from rdkit import Chem\n", + "import codecs\n", + "import numpy as np\n", + "import pandas as pd\n", + "from rdkit.Chem import Descriptors\n", + "from subword_nmt.apply_bpe import BPE" + ] + }, + { + "cell_type": "code", + "execution_count": 10, + "metadata": { + "collapsed": false + }, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "c:\\Users\\Prajwal\\AppData\\Local\\Programs\\Python\\Python39\\lib\\site-packages\\torchmetrics\\utilities\\prints.py:36: UserWarning: Metric `AUROC` will save all targets and predictions in buffer. For large datasets this may lead to large memory footprint.\n", + " warnings.warn(*args, **kwargs)\n" + ] + }, + { + "data": { + "text/plain": [ + "FsrFgLightning(\n", + " (net): FsrFgModel(\n", + " (encoder): Sequential(\n", + " (0): Linear(in_features=5372, out_features=500, bias=True)\n", + " (1): SELU()\n", + " (2): Linear(in_features=500, out_features=100, bias=True)\n", + " )\n", + " (decoder): Sequential(\n", + " (0): Linear(in_features=100, out_features=500, bias=True)\n", + " (1): SELU()\n", + " (2): Linear(in_features=500, out_features=5372, bias=True)\n", + " )\n", + " (dropout): Dropout(p=0.8, inplace=False)\n", + " (batch_norm): BatchNorm1d(100, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n", + " (predictor): Sequential(\n", + " (0): Linear(in_features=100, out_features=200, bias=True)\n", + " (1): SELU()\n", + " (2): BatchNorm1d(200, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n", + " (3): Linear(in_features=200, out_features=100, bias=True)\n", + " (4): SELU()\n", + " (5): BatchNorm1d(100, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n", + " (6): Linear(in_features=100, out_features=50, bias=True)\n", + " (7): SELU()\n", + " (8): BatchNorm1d(50, eps=1e-05, momentum=0.1, affine=True, track_running_stats=True)\n", + " (9): Dropout(p=0.8, inplace=False)\n", + " (10): Linear(in_features=50, out_features=2, bias=True)\n", + " )\n", + " )\n", + " (criterion): CrossEntropyLoss()\n", + " (recon_loss): BCEWithLogitsLoss()\n", + " (softmax): Softmax(dim=1)\n", + " (train_auc): AUROC()\n", + " (valid_auc): AUROC()\n", + " (test_auc): AUROC()\n", + ")" + ] + }, + "execution_count": 10, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "model = FsrFgLightning.load_from_checkpoint('epoch=22-step=5359.ckpt')\n", + "model.eval()" + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "metadata": { + "collapsed": false + }, + "outputs": [], + "source": [ + "def smiles2index(s1, words2idx, bpe):\n", + " t1 = bpe.process_line(s1).split()\n", + " i1 = [words2idx[i] for i in t1]\n", + " return i1\n", + "\n", + "\n", + "def index2multi_hot(i1, idx2word):\n", + " v1 = np.zeros(len(idx2word))\n", + " v1[i1] = 1\n", + " return v1\n", + "\n", + "\n", + "def index2multi_hot_fg(molecule, fgroups_list):\n", + " v1 = np.zeros(len(fgroups_list))\n", + " for idx in range(len(fgroups_list)):\n", + " if molecule.HasSubstructMatch(fgroups_list[idx]):\n", + " v1[idx] = 1\n", + " return v1\n", + "\n", + "\n", + "def smiles2vector_fgr(s1, words2idx, bpe, idx2word, fgroups_list):\n", + " i1 = smiles2index(s1, words2idx, bpe)\n", + " mfg = index2multi_hot(i1, idx2word)\n", + " molecule = Chem.MolFromSmiles(s1)\n", + " fg = index2multi_hot_fg(molecule, fgroups_list)\n", + " return fg, mfg" + ] + }, + { + "cell_type": "code", + "execution_count": 12, + "metadata": { + "collapsed": false + }, + "outputs": [], + "source": [ + "fgroups = pd.read_csv('Functional_groups_filtered.csv')\n", + "fgroups_list = list(map(lambda x: Chem.MolFromSmarts(x), fgroups['SMARTS'].tolist()))\n", + "fgroups_list = [i for i in fgroups_list if i]\n", + "descriptor_funcs = {name: func for name, func in Descriptors.descList}\n", + "\n", + "vocab_path = 'codes_drug_chembl_1500.txt'\n", + "bpe_codes_fin = codecs.open(vocab_path)\n", + "bpe = BPE(bpe_codes_fin, merges=-1, separator='')\n", + "vocab_map = pd.read_csv('subword_units_map_drug_chembl_1500.csv')\n", + "idx2word = vocab_map['index'].values\n", + "words2idx = dict(zip(idx2word, range(0, len(idx2word))))" + ] + }, + { + "cell_type": "code", + "execution_count": 28, + "metadata": { + "collapsed": false + }, + "outputs": [], + "source": [ + "f = open('saff_gen_gpt.txt')\n", + "smiles = f.read().splitlines()\n", + "\n", + "\n" + ] + }, + { + "cell_type": "code", + "execution_count": 29, + "metadata": { + "collapsed": false + }, + "outputs": [ + { + "name": "stderr", + "output_type": "stream", + "text": [ + "100%|██████████| 30/30 [00:01<00:00, 25.86it/s]\n" + ] + } + ], + "source": [ + "from tqdm.auto import tqdm\n", + "import torch\n", + "sm = torch.nn.Softmax(dim = 1)\n", + "preds = []\n", + "probab = []\n", + "for smile in tqdm(smiles):\n", + " fg, mfg = smiles2vector_fgr(smile, words2idx, bpe, idx2word, fgroups_list)\n", + " y_pred, _ = model(fg=torch.Tensor(fg).unsqueeze(0),mfg=torch.Tensor(mfg).unsqueeze(0),num_features=None)\n", + " probabilities = sm(y_pred) \n", + " # print(y_pred)\n", + " # print(probabilities.detach().max().item())\n", + " probab.append(probabilities.detach().max().item())\n", + " # print(int(torch.argmax(y_pred)))\n", + " preds.append(int(torch.argmax(y_pred)))" + ] + }, + { + "cell_type": "code", + "execution_count": 30, + "metadata": { + "collapsed": false + }, + "outputs": [], + "source": [ + "data = {'SMILES': smiles,'Predicted_activity':preds, 'Probability': probab}" + ] + }, + { + "cell_type": "code", + "execution_count": 31, + "metadata": { + "collapsed": false + }, + "outputs": [], + "source": [ + "pd.DataFrame(data).to_csv('moses250.csv',index=False)" + ] + }, + { + "cell_type": "code", + "execution_count": 32, + "metadata": { + "collapsed": false + }, + "outputs": [ + { + "data": { + "text/plain": [ + "0 30\n", + "Name: Predicted_activity, dtype: int64" + ] + }, + "execution_count": 32, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "pd.DataFrame(data)['Predicted_activity'].value_counts()" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "collapsed": false + }, + "outputs": [], + "source": [] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3.9.5 64-bit", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.9.5" + }, + "vscode": { + "interpreter": { + "hash": "a4329ea539b1232b51730207fd9c93849c82cf9ff2a2d6356a1e6b85d15167f8" + } + } + }, + "nbformat": 4, + "nbformat_minor": 0 +} diff --git a/E_coli activity prediction model/train_cli.py b/E_coli activity prediction model/train_cli.py new file mode 100644 index 0000000000000000000000000000000000000000..83851e7695d33d103d50e9f52a7e43490d7db6b7 --- /dev/null +++ b/E_coli activity prediction model/train_cli.py @@ -0,0 +1,82 @@ +from rdkit import Chem +import torch +from torch import nn +from pytorch_lightning import LightningModule +import torchmetrics +from fsr_fg_model import FsrFgModel +from data import FsrFgDataModule +from pytorch_lightning.cli import LightningCLI + + +class FsrFgLightning(LightningModule): + def __init__(self, fg_input_dim=2786, mfg_input_dim=2586, num_input_dim=208, + enc_dec_dims=(500, 100), output_dims=(200, 100, 50), num_tasks=2, dropout=0.8, + method='FGR', lr=1e-4, **kwargs): + super(FsrFgLightning, self).__init__() + self.save_hyperparameters('fg_input_dim', 'mfg_input_dim', 'num_input_dim', 'enc_dec_dims', + 'output_dims', 'num_tasks', 'dropout', 'method', 'lr') + self.net = FsrFgModel(fg_input_dim, mfg_input_dim, num_input_dim, enc_dec_dims, output_dims, num_tasks, dropout, + method) + self.lr = lr + self.method = method + self.criterion = nn.CrossEntropyLoss() + self.recon_loss = nn.BCEWithLogitsLoss() + self.softmax = nn.Softmax(dim=1) + self.train_auc = torchmetrics.AUROC(num_classes=num_tasks) + self.valid_auc = torchmetrics.AUROC(num_classes=num_tasks) + self.test_auc = torchmetrics.AUROC(num_classes=num_tasks) + + def forward(self, fg, mfg, num_features): + if self.method == 'FG': + y_pred = self.net(fg=fg) + elif self.method == 'MFG': + y_pred = self.net(mfg=mfg) + elif self.method == 'FGR': + y_pred = self.net(fg=fg, mfg=mfg) + else: + y_pred = self.net(fg=fg, mfg=mfg, num_features=num_features) + return y_pred + + def configure_optimizers(self): + optimizer = torch.optim.AdamW(self.net.parameters(), lr=self.lr, weight_decay=0.3) + scheduler = torch.optim.lr_scheduler.OneCycleLR( + optimizer, max_lr=1e-2, total_steps=self.trainer.estimated_stepping_batches) + return [optimizer], [scheduler] + + def training_step(self, batch, batch_idx): + fg, mfg, num_features, y = batch + y_pred, recon = self(fg, mfg, num_features) + if self.method == 'FG': + loss_r_pre = 1e-4 * self.recon_loss(recon, fg) + elif self.method == 'MFG': + loss_r_pre = 1e-4 * self.recon_loss(recon, mfg) + else: + loss_r_pre = 1e-4 * self.recon_loss(recon, torch.cat([fg, mfg], dim=1)) + loss = self.criterion(y_pred, y) + loss_r_pre + self.train_auc(self.softmax(y_pred), y) + self.log('train_loss', loss, on_step=True, on_epoch=False, prog_bar=False, logger=True) + self.log('train_auc', self.train_auc, on_epoch=True, on_step=False, prog_bar=True, logger=True) + return loss + + def validation_step(self, batch, batch_idx): + fg, mfg, num_features, y = batch + y_pred, recon = self(fg, mfg, num_features) + loss = self.criterion(y_pred, y) + self.valid_auc(self.softmax(y_pred), y) + self.log('val_loss', loss, on_step=False, on_epoch=True, prog_bar=True, logger=True) + self.log('val_auc', self.valid_auc, on_step=False, on_epoch=True, prog_bar=True, logger=True) + + def test_step(self, batch, batch_idx): + fg, mfg, num_features, y = batch + y_pred, recon = self(fg, mfg, num_features) + loss = self.criterion(y_pred, y) + self.test_auc(self.softmax(y_pred), y) + self.log('test_loss', loss, on_step=False, on_epoch=True, prog_bar=True, logger=True) + self.log('test_auc', self.test_auc, on_step=False, on_epoch=True, prog_bar=True, logger=True) + + +if __name__ == '__main__': + cli = LightningCLI(model_class=FsrFgLightning, datamodule_class=FsrFgDataModule, + save_config_callback=None, run=False) + cli.trainer.fit(cli.model, cli.datamodule) + cli.trainer.test(cli.model, cli.datamodule, ckpt_path='best') diff --git a/Experiments/BACE/bace extract.ipynb b/Experiments/BACE/bace extract.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..0414de9054ddd31803fe5d2faa8a9614a6996a5c --- /dev/null +++ b/Experiments/BACE/bace extract.ipynb @@ -0,0 +1,862 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": 1, + "metadata": {}, + "outputs": [], + "source": [ + "import pandas as pd" + ] + }, + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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molCIDClassModelpIC50MWAlogPHBAHBDRB...PEOE6 (PEOE6)PEOE7 (PEOE7)PEOE8 (PEOE8)PEOE9 (PEOE9)PEOE10 (PEOE10)PEOE11 (PEOE11)PEOE12 (PEOE12)PEOE13 (PEOE13)PEOE14 (PEOE14)canvasUID
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..................................................................
789Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCCCC1)...BACE_8211Test7.000000457.575813.8757239...32.84419668.638565260.466370108.2074223.3021037.9801708.1883270.00000024.663788821
790Fc1ccc(cc1OCCCCF)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC...BACE_8221Test7.000000439.403414.4032409...25.73999248.51122389.019829138.5116136.0943538.9519147.9801700.0000006.970751822
791O=C1N(C)C(=NC1(c1cc(ccc1)-c1cncnc1)c1cn(nc1)C)NBACE_8231Test7.000000347.373900.2846503...25.73999213.182580127.74838097.0191544.0976753.2717397.9801700.0000000.000000823
792FC1(F)CN2C(=NC1)C(N=C2N)(c1cc(ccc1)-c1cncnc1)c...BACE_8241Test7.000000434.441312.6596504...42.89998632.98883158.408638173.9353357.8991433.2717390.000000-1.2735240.000000824
793S1(=O)(=O)CC(Cc2cc(OCCOC)c(N)c(F)c2)C(O)C([NH2...BACE_8251Test7.000000509.653691.78314310...56.65716627.648426167.337080231.5155236.4986340.0000008.1883270.00000024.663788825
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691 rows × 595 columns

\n", + "
" + ], + "text/plain": [ + " mol CID Class \\\n", + "0 O1CC[C@@H](NC(=O)[C@@H](Cc2cc3cc(ccc3nc2N)-c2c... BACE_1 1 \n", + "1 Fc1cc(cc(F)c1)C[C@H](NC(=O)[C@@H](N1CC[C@](NC(... BACE_2 1 \n", + "2 S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)N[C@H](... BACE_3 1 \n", + "3 S1(=O)(=O)C[C@@H](Cc2cc(O[C@H](COCC)C(F)(F)F)c... BACE_4 1 \n", + "4 S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)CC1)C(=O)N[C@H](... BACE_5 1 \n", + ".. ... ... ... \n", + "789 Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCCCC1)... BACE_821 1 \n", + "790 Fc1ccc(cc1OCCCCF)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC... BACE_822 1 \n", + "791 O=C1N(C)C(=NC1(c1cc(ccc1)-c1cncnc1)c1cn(nc1)C)N BACE_823 1 \n", + "792 FC1(F)CN2C(=NC1)C(N=C2N)(c1cc(ccc1)-c1cncnc1)c... BACE_824 1 \n", + "793 S1(=O)(=O)CC(Cc2cc(OCCOC)c(N)c(F)c2)C(O)C([NH2... BACE_825 1 \n", + "\n", + " Model pIC50 MW AlogP HBA HBD RB ... PEOE6 (PEOE6) \\\n", + "0 Train 9.154901 431.56979 4.4014 3 2 5 ... 53.205711 \n", + "1 Train 8.853872 657.81073 2.6412 5 4 16 ... 73.817162 \n", + "2 Train 8.698970 591.74091 2.5499 4 3 11 ... 70.365707 \n", + "3 Train 8.698970 591.67828 3.1680 4 3 12 ... 56.657166 \n", + "4 Train 8.698970 629.71283 3.5086 3 3 11 ... 78.945702 \n", + ".. ... ... ... ... ... ... .. ... ... \n", + "789 Test 7.000000 457.57581 3.8757 2 3 9 ... 32.844196 \n", + "790 Test 7.000000 439.40341 4.4032 4 0 9 ... 25.739992 \n", + "791 Test 7.000000 347.37390 0.2846 5 0 3 ... 25.739992 \n", + "792 Test 7.000000 434.44131 2.6596 5 0 4 ... 42.899986 \n", + "793 Test 7.000000 509.65369 1.7831 4 3 10 ... 56.657166 \n", + "\n", + " PEOE7 (PEOE7) PEOE8 (PEOE8) PEOE9 (PEOE9) PEOE10 (PEOE10) \\\n", + "0 78.640335 226.855410 107.43491 37.133846 \n", + "1 47.171600 365.676940 174.07675 34.923889 \n", + "2 47.941147 192.406520 255.75255 23.654478 \n", + "3 37.954151 194.353040 202.76335 36.498634 \n", + "4 39.361153 179.712880 220.46130 23.654478 \n", + ".. ... ... ... ... \n", + "789 68.638565 260.466370 108.20742 23.302103 \n", + "790 48.511223 89.019829 138.51161 36.094353 \n", + "791 13.182580 127.748380 97.01915 44.097675 \n", + "792 32.988831 58.408638 173.93533 57.899143 \n", + "793 27.648426 167.337080 231.51552 36.498634 \n", + "\n", + " PEOE11 (PEOE11) PEOE12 (PEOE12) PEOE13 (PEOE13) PEOE14 (PEOE14) \\\n", + "0 0.000000 7.980170 0.000000 0.000000 \n", + "1 7.980170 24.148668 0.000000 24.663788 \n", + "2 0.230159 15.879790 0.000000 24.663788 \n", + "3 0.980913 8.188327 0.000000 26.385181 \n", + "4 0.230159 15.879790 0.000000 26.100143 \n", + ".. ... ... ... ... \n", + "789 7.980170 8.188327 0.000000 24.663788 \n", + "790 8.951914 7.980170 0.000000 6.970751 \n", + "791 3.271739 7.980170 0.000000 0.000000 \n", + "792 3.271739 0.000000 -1.273524 0.000000 \n", + "793 0.000000 8.188327 0.000000 24.663788 \n", + "\n", + " canvasUID \n", + "0 1 \n", + "1 2 \n", + "2 3 \n", + "3 4 \n", + "4 5 \n", + ".. ... \n", + "789 821 \n", + "790 822 \n", + "791 823 \n", + "792 824 \n", + "793 825 \n", + "\n", + "[691 rows x 595 columns]" + ] + }, + "execution_count": 4, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "\n", + "df" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [], + "source": [ + "import numpy as np\n", + "np.savetxt(r'bace.txt', df.mol.values, fmt='%s')" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.9.5" + }, + "orig_nbformat": 4, + "vscode": { + "interpreter": { + "hash": "a4329ea539b1232b51730207fd9c93849c82cf9ff2a2d6356a1e6b85d15167f8" + } + } + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/Experiments/BACE/bace.csv b/Experiments/BACE/bace.csv new file mode 100644 index 0000000000000000000000000000000000000000..fd455690cb2876cfbcd5ae0a9ffd1e7194291091 --- /dev/null +++ b/Experiments/BACE/bace.csv @@ -0,0 +1,1514 @@ +mol,CID,Class,Model,pIC50,MW,AlogP,HBA,HBD,RB,HeavyAtomCount,ChiralCenterCount,ChiralCenterCountAllPossible,RingCount,PSA,Estate,MR,Polar,sLi_Key,ssBe_Key,ssssBem_Key,sBH2_Key,ssBH_Key,sssB_Key,ssssBm_Key,sCH3_Key,dCH2_Key,ssCH2_Key,tCH_Key,dsCH_Key,aaCH_Key,sssCH_Key,ddC_Key,tsC_Key,dssC_Key,aasC_Key,aaaC_Key,ssssC_Key,sNH3_Key,sNH2_Key,ssNH2_Key,dNH_Key,ssNH_Key,aaNH_Key,tN_Key,sssNH_Key,dsN_Key,aaN_Key,sssN_Key,ddsN_Key,aasN_Key,ssssN_Key,daaN_Key,sOH_Key,dO_Key,ssO_Key,aaO_Key,aOm_Key,sOm_Key,sF_Key,sSiH3_Key,ssSiH2_Key,sssSiH_Key,ssssSi_Key,sPH2_Key,ssPH_Key,sssP_Key,dsssP_Key,ddsP_Key,sssssP_Key,sSH_Key,dS_Key,ssS_Key,aaS_Key,dssS_Key,ddssS_Key,ssssssS_Key,Sm_Key,sCl_Key,sGeH3_Key,ssGeH2_Key,sssGeH_Key,ssssGe_Key,sAsH2_Key,ssAsH_Key,sssAs_Key,dsssAs_Key,ddsAs_Key,sssssAs_Key,sSeH_Key,dSe_Key,ssSe_Key,aaSe_Key,dssSe_Key,ssssssSe_Key,ddssSe_Key,sBr_Key,sSnH3_Key,ssSnH2_Key,sssSnH_Key,ssssSn_Key,sI_Key,sPbH3_Key,ssPbH2_Key,sssPbH_Key,ssssPb_Key,sLi_Cnt,ssBe_Cnt,ssssBem_Cnt,sBH2_Cnt,ssBH_Cnt,sssB_Cnt,ssssBm_Cnt,sCH3_Cnt,dCH2_Cnt,ssCH2_Cnt,tCH_Cnt,dsCH_Cnt,aaCH_Cnt,sssCH_Cnt,ddC_Cnt,tsC_Cnt,dssC_Cnt,aasC_Cnt,aaaC_Cnt,ssssC_Cnt,sNH3_Cnt,sNH2_Cnt,ssNH2_Cnt,dNH_Cnt,ssNH_Cnt,aaNH_Cnt,tN_Cnt,sssNH_Cnt,dsN_Cnt,aaN_Cnt,sssN_Cnt,ddsN_Cnt,aasN_Cnt,ssssN_Cnt,daaN_Cnt,sOH_Cnt,dO_Cnt,ssO_Cnt,aaO_Cnt,aOm_Cnt,sOm_Cnt,sF_Cnt,sSiH3_Cnt,ssSiH2_Cnt,sssSiH_Cnt,ssssSi_Cnt,sPH2_Cnt,ssPH_Cnt,sssP_Cnt,dsssP_Cnt,ddsP_Cnt,sssssP_Cnt,sSH_Cnt,dS_Cnt,ssS_Cnt,aaS_Cnt,dssS_Cnt,ddssS_Cnt,ssssssS_Cnt,Sm_Cnt,sCl_Cnt,sGeH3_Cnt,ssGeH2_Cnt,sssGeH_Cnt,ssssGe_Cnt,sAsH2_Cnt,ssAsH_Cnt,sssAs_Cnt,dsssAs_Cnt,ddsAs_Cnt,sssssAs_Cnt,sSeH_Cnt,dSe_Cnt,ssSe_Cnt,aaSe_Cnt,dssSe_Cnt,ssssssSe_Cnt,ddssSe_Cnt,sBr_Cnt,sSnH3_Cnt,ssSnH2_Cnt,sssSnH_Cnt,ssssSn_Cnt,sI_Cnt,sPbH3_Cnt,ssPbH2_Cnt,sssPbH_Cnt,ssssPb_Cnt,sLi_Sum,ssBe_Sum,ssssBem_Sum,sBH2_Sum,ssBH_Sum,sssB_Sum,ssssBm_Sum,sCH3_Sum,dCH2_Sum,ssCH2_Sum,tCH_Sum,dsCH_Sum,aaCH_Sum,sssCH_Sum,ddC_Sum,tsC_Sum,dssC_Sum,aasC_Sum,aaaC_Sum,ssssC_Sum,sNH3_Sum,sNH2_Sum,ssNH2_Sum,dNH_Sum,ssNH_Sum,aaNH_Sum,tN_Sum,sssNH_Sum,dsN_Sum,aaN_Sum,sssN_Sum,ddsN_Sum,aasN_Sum,ssssN_Sum,daaN_Sum,sOH_Sum,dO_Sum,ssO_Sum,aaO_Sum,aOm_Sum,sOm_Sum,sF_Sum,sSiH3_Sum,ssSiH2_Sum,sssSiH_Sum,ssssSi_Sum,sPH2_Sum,ssPH_Sum,sssP_Sum,dsssP_Sum,ddsP_Sum,sssssP_Sum,sSH_Sum,dS_Sum,ssS_Sum,aaS_Sum,dssS_Sum,ddssS_Sum,ssssssS_Sum,Sm_Sum,sCl_Sum,sGeH3_Sum,ssGeH2_Sum,sssGeH_Sum,ssssGe_Sum,sAsH2_Sum,ssAsH_Sum,sssAs_Sum,dsssAs_Sum,ddsAs_Sum,sssssAs_Sum,sSeH_Sum,dSe_Sum,ssSe_Sum,aaSe_Sum,dssSe_Sum,ssssssSe_Sum,ddssSe_Sum,sBr_Sum,sSnH3_Sum,ssSnH2_Sum,sssSnH_Sum,ssssSn_Sum,sI_Sum,sPbH3_Sum,ssPbH2_Sum,sssPbH_Sum,ssssPb_Sum,sLi_Avg,ssBe_Avg,ssssBem_Avg,sBH2_Avg,ssBH_Avg,sssB_Avg,ssssBm_Avg,sCH3_Avg,dCH2_Avg,ssCH2_Avg,tCH_Avg,dsCH_Avg,aaCH_Avg,sssCH_Avg,ddC_Avg,tsC_Avg,dssC_Avg,aasC_Avg,aaaC_Avg,ssssC_Avg,sNH3_Avg,sNH2_Avg,ssNH2_Avg,dNH_Avg,ssNH_Avg,aaNH_Avg,tN_Avg,sssNH_Avg,dsN_Avg,aaN_Avg,sssN_Avg,ddsN_Avg,aasN_Avg,ssssN_Avg,daaN_Avg,sOH_Avg,dO_Avg,ssO_Avg,aaO_Avg,aOm_Avg,sOm_Avg,sF_Avg,sSiH3_Avg,ssSiH2_Avg,sssSiH_Avg,ssssSi_Avg,sPH2_Avg,ssPH_Avg,sssP_Avg,dsssP_Avg,ddsP_Avg,sssssP_Avg,sSH_Avg,dS_Avg,ssS_Avg,aaS_Avg,dssS_Avg,ddssS_Avg,ssssssS_Avg,Sm_Avg,sCl_Avg,sGeH3_Avg,ssGeH2_Avg,sssGeH_Avg,ssssGe_Avg,sAsH2_Avg,ssAsH_Avg,sssAs_Avg,dsssAs_Avg,ddsAs_Avg,sssssAs_Avg,sSeH_Avg,dSe_Avg,ssSe_Avg,aaSe_Avg,dssSe_Avg,ssssssSe_Avg,ddssSe_Avg,sBr_Avg,sSnH3_Avg,ssSnH2_Avg,sssSnH_Avg,ssssSn_Avg,sI_Avg,sPbH3_Avg,ssPbH2_Avg,sssPbH_Avg,ssssPb_Avg,First Zagreb (ZM1),First Zagreb index by valence vertex degrees (ZM1V),Second Zagreb (ZM2),Second Zagreb index by valence vertex degrees (ZM2V),Polarity (Pol),Narumi Simple Topological (NST),Narumi Harmonic Topological (NHT),Narumi Geometric Topological (NGT),Total structure connectivity (TSC),Wiener (W),Mean Wiener (MW),Xu (Xu),Quadratic (QIndex),Radial centric (RC),Mean Square Distance Balaban (MSDB),Superpendentic (SP),Harary (Har),Log of product of row sums (LPRS),Pogliani (Pog),Schultz Molecular Topological (SMT),Schultz Molecular Topological by valence vertex degrees (SMTV),Mean Distance Degree Deviation (MDDD),Ramification (Ram),Gutman Molecular Topological (GMT),Gutman MTI by valence vertex degrees (GMTV),Average vertex distance degree (AVDD),Unipolarity (UP),Centralization (CENT),Variation (VAR),Molecular electrotopological variation (MEV),Maximal electrotopological positive variation (MEPV),Maximal electrotopological negative variation (MENV),Eccentric connectivity (ECCc),Eccentricity (ECC),Average eccentricity (AECC),Eccentric (DECC),Valence connectivity index chi-0 (vX0),Valence connectivity index chi-1 (vX1),Valence connectivity index chi-2 (vX2),Valence connectivity index chi-3 (vX3),Valence connectivity index chi-4 (vX4),Valence connectivity index chi-5 (vX5),Average valence connectivity index chi-0 (AvX0),Average valence connectivity index chi-1 (AvX1),Average valence connectivity index chi-2 (AvX2),Average valence connectivity index chi-3 (AvX3),Average valence connectivity index chi-4 (AvX4),Average valence connectivity index chi-5 (AvX5),Quasi Wiener (QW),First Mohar (FM),Second Mohar (SM),Spanning tree number (STN),Kier benzene-likeliness index (KBLI),Topological charge index of order 1 (TCI1),Topological charge index of order 2 (TCI2),Topological charge index of order 3 (TCI3),Topological charge index of order 4 (TCI4),Topological charge index of order 5 (TCI5),Topological charge index of order 6 (TCI6),Topological charge index of order 7 (TCI7),Topological charge index of order 8 (TCI8),Topological charge index of order 9 (TCI9),Topological charge index of order 10 (TCI10),Mean topological charge index of order 1 (MTCI1),Mean topological charge index of order 2 (MTCI2),Mean topological charge index of order 3 (MTCI3),Mean topological charge index of order 4 (MTCI4),Mean topological charge index of order 5 (MTCI5),Mean topological charge index of order 6 (MTCI6),Mean topological charge index of order 7 (MTCI7),Mean topological charge index of order 8 (MTCI8),Mean topological charge index of order 9 (MTCI9),Mean topological charge index of order 10 (MTCI10),Global topological charge (GTC),Hyper-distance-path index (HDPI),Reciprocal hyper-distance-path index (RHDPI),Square reciprocal distance sum (SRDS),Modified Randic connectivity (MRC),Balaban centric (BC),Lopping centric (LC),Kier Hall electronegativity (KHE),Sum of topological distances between N..N (STD(N N)),Sum of topological distances between N..O (STD(N O)),Sum of topological distances between N..S (STD(N S)),Sum of topological distances between N..P (STD(N P)),Sum of topological distances between N..F (STD(N F)),Sum of topological distances between N..Cl (STD(N Cl)),Sum of topological distances between N..Br (STD(N Br)),Sum of topological distances between N..I (STD(N I)),Sum of topological distances between O..O (STD(O O)),Sum of topological distances between O..S (STD(O S)),Sum of topological distances between O..P (STD(O P)),Sum of topological distances between O..F (STD(O F)),Sum of topological distances between O..Cl (STD(O Cl)),Sum of topological distances between O..Br (STD(O Br)),Sum of topological distances between O..I (STD(O I)),Sum of topological distances between S..S (STD(S S)),Sum of topological distances between S..P (STD(S P)),Sum of topological distances between S..F (STD(S F)),Sum of topological distances between S..Cl (STD(S Cl)),Sum of topological distances between S..Br (STD(S Br)),Sum of topological distances between S..I (STD(S I)),Sum of topological distances between P..P (STD(P P)),Sum of topological distances between P..F (STD(P F)),Sum of topological distances between P..Cl (STD(P Cl)),Sum of topological distances between P..Br (STD(P Br)),Sum of topological distances between P..I (STD(P I)),Sum of topological distances between F..F (STD(F F)),Sum of topological distances between F..Cl (STD(F Cl)),Sum of topological distances between F..Br (STD(F Br)),Sum of topological distances between F..I (STD(F I)),Sum of topological distances between Cl..Cl (STD(Cl Cl)),Sum of topological distances between Cl..Br (STD(Cl Br)),Sum of topological distances between Cl..I (STD(Cl I)),Sum of topological distances between Br..Br (STD(Br Br)),Sum of topological distances between Br..I (STD(Br I)),Sum of topological distances between I..I (STD(I I)),Wiener-type index from Z weighted distance matrix - Barysz matrix (WhetZ),Wiener-type index from electronegativity weighted distance matrix (Whete),Wiener-type index from mass weighted distance matrix (Whetm),Wiener-type index from van der waals weighted distance matrix (Whetv),Wiener-type index from polarizability weighted distance matrix (Whetp),Balaban-type index from Z weighted distance matrix - Barysz matrix (JhetZ),Balaban-type index from electronegativity weighted distance matrix (Jhete),Balaban-type index from mass weighted distance matrix (Jhetm),Balaban-type index from van der waals weighted distance matrix (Jhetv),Balaban-type index from polarizability weighted distance matrix (Jhetp),Topological diameter (TD),Topological radius (TR),Petitjean 2D shape (PJ2DS),Balaban distance connectivity index (J),Solvation connectivity index chi-0 (SCIX0),Solvation connectivity index chi-1 (SCIX1),Solvation connectivity index chi-2 (SCIX2),Solvation connectivity index chi-3 (SCIX3),Solvation connectivity index chi-4 (SCIX4),Solvation connectivity index chi-5 (SCIX5),Connectivity index chi-0 (CIX0),Connectivity chi-1 [Randic connectivity] (CIX1),Connectivity index chi-2 (CIX2),Connectivity index chi-3 (CIX3),Connectivity index chi-4 (CIX4),Connectivity index chi-5 (CIX5),Average connectivity index chi-0 (ACIX0),Average connectivity index chi-1 (ACIX1),Average connectivity index chi-2 (ACIX2),Average connectivity index chi-3 (ACIX3),Average connectivity index chi-4 (ACIX4),Average connectivity index chi-5 (ACIX5),reciprocal distance Randic-type index (RDR),reciprocal distance square Randic-type index (RDSR),1-path Kier alpha-modified shape index (KAMS1),2-path Kier alpha-modified shape index (KAMS2),3-path Kier alpha-modified shape index (KAMS3),Kier flexibility (KF),path/walk 2 - Randic shape index (RSIpw2),path/walk 3 - Randic shape index (RSIpw3),path/walk 4 - Randic shape index (RSIpw4),path/walk 5 - Randic shape index (RSIpw5),E-state topological parameter (ETP),Ring Count 3 (RNGCNT3),Ring Count 4 (RNGCNT4),Ring Count 5 (RNGCNT5),Ring Count 6 (RNGCNT6),Ring Count 7 (RNGCNT7),Ring Count 8 (RNGCNT8),Ring Count 9 (RNGCNT9),Ring Count 10 (RNGCNT10),Ring Count 11 (RNGCNT11),Ring Count 12 (RNGCNT12),Ring Count 13 (RNGCNT13),Ring Count 14 (RNGCNT14),Ring Count 15 (RNGCNT15),Ring Count 16 (RNGCNT16),Ring Count 17 (RNGCNT17),Ring Count 18 (RNGCNT18),Ring Count 19 (RNGCNT19),Ring Count 20 (RNGCNT20),Atom Count (ATMCNT),Bond Count (BNDCNT),Atoms in Ring System (ATMRNGCNT),Bonds in Ring System (BNDRNGCNT),Cyclomatic number (CYCLONUM),Number of ring systems (NRS),Normalized number of ring systems (NNRS),Ring Fusion degree (RFD),Ring perimeter (RNGPERM),Ring bridge count (RNGBDGE),Molecule cyclized degree (MCD),Ring Fusion density (RFDELTA),Ring complexity index (RCI),Van der Waals surface area (VSA),MR1 (MR1),MR2 (MR2),MR3 (MR3),MR4 (MR4),MR5 (MR5),MR6 (MR6),MR7 (MR7),MR8 (MR8),ALOGP1 (ALOGP1),ALOGP2 (ALOGP2),ALOGP3 (ALOGP3),ALOGP4 (ALOGP4),ALOGP5 (ALOGP5),ALOGP6 (ALOGP6),ALOGP7 (ALOGP7),ALOGP8 (ALOGP8),ALOGP9 (ALOGP9),ALOGP10 (ALOGP10),PEOE1 (PEOE1),PEOE2 (PEOE2),PEOE3 (PEOE3),PEOE4 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+s1cc(cc1)-c1cc2c(nc(N)cc2)cc1 +Clc1cc(C[NH+]2CCC(NC(=O)COc3ccc(S(=O)(=O)N)cc3C)CC2)c(OC(C)C)c(OC)c1 +Clc1cc(C[NH+]2CCC(NC(=O)COc3ccc(S(=O)(=O)N)cc3)CC2)c(OC(C)C)c(OC)c1 +Oc1ccc(cc1C1CCCCC1)CC[NH3+] +Oc1ccc(cc1CC)CC[NH3+] +Oc1ccc(cc1)CC([NH3+])C +Oc1ccc(cc1)CC[NH3+] +O=C(NCCC(C)(C)C)C(Cc1cc2cc(ccc2nc1N)-c1ccccc1C)C +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(O)C1 +Fc1cc(ccc1C)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1cc(ccc1)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(c1)/C(=N\OC)/C)C(=O)N(CCC)CCC)C(O)C[NH2+]Cc1cc(OC)ccc1 +S(=O)(=O)(N(C)c1cc2cc(NCCCCOc3cc(CC(NC2=O)C(O)C[NH2+]Cc2cc(ccc2)C(C)C)ccc3)c1)CCC +O1CCCCOc2cc(CC(NC(=O)c3cc(N4CCCC4=O)cc1c3)C(O)C[NH2+]C1(CC1)c1cc(ccc1)C(C)C)ccc2 +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCc2cccnc2)C1 +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCc2ncccc2)C1 +s1ccnc1-c1cc(cc(F)c1)CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1cc(cc(c1)C#C)CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1cc(ccc1F)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(c1)C(=O)N(CCC)CCC)C(O)C)C(O)C[NH2+]Cc1cc(OC)ccc1 +S(=O)(=O)(N(C)c1cc2cc(NCCCCOc3cc(CC(NC2=O)C(O)C[NH2+]C2(CC2)c2cc(ccc2)C(C)C)ccc3)c1)CCC +S1(=O)(=O)CC(Cc2cc(OC(C(F)(F)F)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 +S1(=O)(=O)CC(Cc2cc(O[C@H](COC)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 +S1(=O)(=O)CC(Cc2cc(OC(C(F)(F)F)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(O)(C)C)C1 +S1(=O)(=O)CC(Cc2cc(OC(C(F)(F)F)C(F)(F)F)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(CO)(C)C)C1 +Fc1ccc(cc1OC(F)(F)F)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +FC(F)(F)c1cc(ccc1)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1ccc(cc1C#N)CC(NC(=O)C)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2 +Fc1c2c(ccc1)C(N=C2N)(C=1C=C(C)C(=O)N(C=1)CC)c1cc(NC(=O)c2ncccc2)ccc1 +O=C(NCC1CCCCC1)C(Cc1cc2cc(ccc2nc1N)-c1ccccc1C)C +O1c2c(cc(cc2)CC)C([NH2+]CC(O)C2NC(=O)C=3C=C(N4CCCC4)C(=O)N(CCCCc4cc(C2)ccc4)C=3)CC12CCC2 +Fc1c2c(cc(F)c1)C(N=C2N)(C=1C=C(C)C(=O)N(C=1)CC)c1cc(ccc1)-c1cc(cnc1)C#CC +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCCC)C1 +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(Oc2ccccc2)C1 +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(Oc2ncccc2)C1 +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(NC(=O)C)(C(CC)C)C1=O)CCc1ccccc1)C(O)C1[NH2+]CC(OCc2cc(ccc2)C(F)(F)F)C1 +O1c2ncc(cc2C([NH2+]CC(O)C2NC(=O)C=3C=CC(=O)N(CCCc4cc(C2)ccc4)C=3)CC12CCC2)CC(C)(C)C +Fc1ccc(cc1CC(NC(=O)COC)C(O)C[NH2+]C1CC2(Oc3ncc(cc13)CC(C)(C)C)CCC2)C#C +Fc1cc(cc(F)c1)CC(NC(=O)c1cc(cc(c1)/C(=N\O)/C)C(=O)N(CCC)CCC)C(O)C[NH2+]Cc1cc(OC)ccc1 +S1(=O)(=O)N(c2cc(cc3n(cc(CC1)c23)CC)C(=O)NC([C@H](O)C[NH2+]CCC(F)(F)F)Cc1ccccc1)C 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+O=C(NCc1cccnc1)C(Cc1cc2cc(ccc2nc1N)-c1ccccc1C)C +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(CC(C)C)C1=O)C)C(O)C[NH2+]Cc1cc(OC)ccc1 +Fc1c(cccc1OC)-c1cc(ccc1)C1(N=C(N2C1=NCCC2)N)c1ccncc1 +S1(=O)(=O)N(CCCC1)c1cc(cc(c1)C(=O)N[C@H]([C@@H](O)C[NH2+]Cc1cc(OC)ccc1)Cc1cc(F)cc(F)c1)C(=O)C +O(C)c1cc(ccc1OC)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1 +O1CCOc2c1cc(cc2)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1cccnc1 +FC(F)Oc1ccc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)CCC +FC(F)Oc1ccc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)CCCCC +FC(F)Oc1ccc(cc1)[C@@]1(N=C(N)N(C)C1=O)c1cc(ccc1)\C=C\C1CC1 +s1cc(cc1)C1(N=C(N)N(C)C1=O)c1cc(-c2cccnc2)c(F)cc1 +s1cc(cc1)C1(N=C(N)N(C)C1=O)c1cc(ccc1)-c1nccnc1 +S1(=O)(=O)N(CCCC1)c1cc(cc(NCC)c1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C1CCOCC1 +S1(=O)(=O)N(c2cc(cc3c2n(cc3CC)C1)C(=O)NC(Cc1ccccc1)C(O)C[NH2+]C)C +O1c2ncc(cc2C([NH2+]CC(O)C(NC(=O)C)Cc2ccccc2)CC12CCC2)CC +O(C)c1ccc(cc1)C1(N=C(N2C1=NCCC2)N)c1cc(ccc1)-c1cccnc1 +Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCc2nc(ncc2C1)C)c1cc(ccc1)C(C)(C)C +S(=O)(=O)(Nc1cc(cc(c1)C(C)(C)C)C1([NH2+]CC(O)C(NC(=O)C)Cc2cc(F)cc(F)c2)CCCCC1)C +S1(=O)(=O)CC(Cc2cc(C3CC3)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 +Fc1cc(cc(F)c1)CC(NC(=O)C(N1CCC(CCCC)C1=O)C)C(O)C1[NH2+]CC(O)C1 +Clc1ccc(nc1)C(=O)Nc1cc(C2(N=C(N)C3C(C2)C3)C)c(F)cc1 +O(C)c1cccnc1-c1cc2cc(CC(C(=O)NCCC(C)(C)C)C)c(nc2cc1)N +O(C)c1ccc(cc1C)C1(N=C(C)C(=N1)N)c1cc(ccc1)-c1cncnc1 +Fc1cc(ccc1)-c1cc2c(OC(CC23N=C(N)N(C)C3=O)(C)C)cc1 +O(C)c1ccc(cc1)[C@@]1([NH+]=C(N2C1=NCCC2)N)c1cc(ccc1)-c1cncnc1 +Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCC(NOC)CC1)c1cc(ccc1)C(C)(C)C +o1cccc1C(=O)Nc1cc(ccc1)C1(N=C(N)N(C)C1=O)C1CCCCC1 +O=C1N(C)C(=N[C@@]1(c1cc(ccc1)-c1cccnc1)c1cc(ncc1)C)N +Fc1cc(cc(F)c1)CC(NC(=O)C)C(O)C[NH2+]C1(CCCCC1)c1cc(ccc1)C(C)=C +Fc1ccc(cc1OCCCCF)[C@]1(N=C(N)N(C)C1=O)c1ccc(OC(F)F)cc1 +O=C1N(C)C(=NC1(c1cc(ccc1)-c1cncnc1)c1cn(nc1)C)N +FC1(F)CN2C(=NC1)C(N=C2N)(c1cc(ccc1)-c1cncnc1)c1ccc(OC)cc1 +S1(=O)(=O)CC(Cc2cc(OCCOC)c(N)c(F)c2)C(O)C([NH2+]Cc2cc(ccc2)C(C)(C)C)C1 diff --git a/Experiments/BACE/outputs/FSR/bace_fsr.txt b/Experiments/BACE/outputs/FSR/bace_fsr.txt new file mode 100644 index 0000000000000000000000000000000000000000..7266c2657723873e6a7a46e073b4d025c6dcc25a --- /dev/null +++ b/Experiments/BACE/outputs/FSR/bace_fsr.txt @@ -0,0 +1,100 @@ +CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)C(C)C2=O)cn1 +Nc1nc2ccccc2cc1CCC(=O)NCC1CCCCC1 +COc1ccc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc1OC +CN1C(=O)CC(C)(c2cc(-c3cccc(C#N)c3)cs2)N=C1N +CC1=N[C](c2cccc(-c3cncc(C#N)c3)c2)C(=O)N1C +CCn1cc(C2(c3cccc(-c4nccs4)c3)N=C(N)N(C)C2=O)cn1 +CN1C(=O)CC(C)(c2cc(-c3cccc(C#N)c3)cs2)N=C1N +NC1=[N+]C(c2cccc(-c3cccnc3)c2)(c2cccc(-c3cncnc3)c2)C2=NCCCN21 +COc1cc(C)cc(C[N+]2CCC(NC(=O)c3ccc(S(N)(=O)=O)cc3C)CC2)c1OC(C)C +CC(C)CCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +COc1ccc(C2(c3cccc(-c4cccnc4)c3)[N+]=C(N)N3CCCN=C32)cc1 +CCCCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +CCOc1ccc(-c2nsc(C)c2C(=O)NC(N)NCc2cc(C)c(NC(C)=O)c(C)c2)cc1 +NC1=[N+]C(C2=CC(c3cncnc3)=C2)(c2cccc(-c3cccnc3)c2)C2=NCCCN21 +Cc1ccoc1-c1ccc2c(n1)C1(CC(C)(C)O2)N=C(N)N(C)C1=O +NC1=NC(c2cccc(-c3cncnc3)c2)(c2ccnc(-c3cncnc3)c2)c2ccccc21 +NC1=NC(c2cccc(-c3cccnc3)c2)(c2cccc(-c3cncnc3)c2)C2=NCCCN12 +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1C +Cc1ccccc1-c1ccc2nc(N)c(CCC(=O)NCC3CCCCC3)cc2c1 +CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +Cc1ccc(C(=O)Nc2cccc(C3(C)N=C(N)N(C)C3=O)c2)nc1 +CCCCCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CN1C(=O)C(c2cccc(-c3cccnc3)c2)(c2cnn(CCC(C)(C)C)c2)N=C1N +CC(C)CCCCCCCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +CCn1cc(C2(c3cccc(NC(=O)c4occc4C)c3)N=C(N)N(C)C2=O)cn1 +CCn1cc(C2(c3cccc(-c4nccs4)c3)N=C(N)N(C)C2=O)cn1 +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1 +CCCCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +NC1=[N+]C(c2cccc(-c3cccnc3)c2)(c2cccc(-c3cncnc3)c2)C2=NCCCN21 +COc1ccc(C2(c3cccc(-c4cncnc4)c3)[N+]=C(N)N3CCCN=C32)cc1C +CCc1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)ccn1 +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1C +CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CN1C(=O)C(c2cccc(-c3cncnc3)c2)(c2cnn(CCC(C)(C)C)c2)N=C1N +CCCCCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CC(C)CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CCC(Cc1cc2cc(-c3ccccc3C)ccc2nc1N)C(=O)NCC1CCCCC1 +COc1ccc(-c2ccc3ncn(CC(=O)NC(=[N+2])NCc4cc(C)c(NC(C)=O)c(C)c4)c3c2)cc1 +NC1=[N+]C(c2cccc(-c3cncnc3)c2)(c2cccc(-c3cncnc3)c2)C2=NCCCN21 +COc1cccc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)c1 +COc1ccc(C2(c3cccc(-c4cncnc4)c3)[N+]=C(N)N3CCCN=C32)cc1OC +CCCCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +CCCCCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +CCC(CO)c1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cs1 +CN1C(=O)C(c2cccc(-c3cncnc3)c2)(c2ccnc(C3CCCCC3)c2)N=C1N +COc1ccc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc1C +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1 +CCC(=O)c1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cs1 +CN1C(=O)C(c2cccc(-c3cccnc3)c2)(c2ccc3c(c2)OCCO3)N=C1N +NC1=[N+]C(c2cccc(-c3ccccc3)c2)(c2ccnc(C3CC3)c2)C2=NCCCN21 +CN1C(=O)C2(CC(C)(C)Cc3ccc(-c4cccnc4)cc32)N=C1N +CCc1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)nc(CC)n1 +CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CCCCCCCCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(C)N(C)C2=O)cn1 +CCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +CC1(c2cccc(NC(=O)c3ccc(C#N)cn3)c2)[C]COC(N)=N1 +COc1ccc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc1C +CN1C(=O)C(c2ccsc2)(c2cccc(-c3cccnc3)c2)N=C1N +CCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +CN1C(=O)C2(CC(C)(C)Cc3ccc(-c4cccnc4)cc32)N=C1N +NC1=[N+]C(c2cccc(-c3cccnc3)c2)(c2cccc(-c3cncnc3)c2)C2=NCCCN21 +CC(C)CCCCCCCCCCCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +COc1ccc(C2(c3cccc(-c4ccncc4)c3)N=C(N)N(C)C2=O)cc1C +CCC(CC)Cn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +COc1ccc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc1C +CCCc1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc(C)n1 +CN1C(=O)C(c2ccncc2)(c2cccc(-c3cccnc3)c2)N=C1N +CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CCn1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +COc1ccc(C2(c3cccc(-c4cncnc4)c3)[N+]=C(N)N3CCCN=C32)cc1 +CCC(=O)Oc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1OC +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1C +NC1=[N+]C(c2ccncc2)(c2cccc(-c3cccnc3)c2)C2=NCCCN21 +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1C +CN1C(=O)C(c2cccc(-c3ccccc3)c2)(C2CCCCCCCCCCCCCCCC2)N=C1N +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1 +CN1C(=O)C2(CC(C)(C)Cc3ccc(-c4cccnc4)cc32)N=C1N +CN1C(=O)C(c2ccsc2)(c2cccc(-c3cccnc3)c2)N=C1N +CN1C(=O)C2(CC(C)(C)Cc3ccc(-c4cccnc4)cc32)N=C1N +CN1C(=O)C(c2ccsc2)(c2cccc(-c3cncnc3)c2)N=C1N +COc1ccc(C2(c3cccc(-c4cncnc4)c3)[N+]=C(N)N3CCCN=C32)cc1C +COc1ccc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc1C +CC(C)Cn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +NC1=[N+]C(c2ccsc2)(c2cccc(-c3cncnc3)c2)C2=NCCCN21 +CCC(C)Cn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CCC(C)Cn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1C +COc1ccc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc1C +CN1C(=O)C(c2cccc(-c3cncnc3)c2)(c2ccnc(C3CCCCC3)c2)N=C1N +Cc1ccc(C(=O)Nc2cccc(C3(C4CCCCCCCCCCCCCCCC4)N=C(N)N(C)C3=O)c2)nc1 +CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CN1C(=O)C(c2ccsc2)(c2cccc(-c3cccnc3)c2)N=C1N +CCn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CN1C(=O)C(c2ccsc2)(c2cccc(-c3cccnc3)c2)N=C1N +Cc1ccccc1-c1ccc2nc(N)c(CC(C)C(=O)NCCC(C)(C)C)cc2c1 +CC(C)Cn1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cn1 +CC(C)n1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cn1 +CN1C(=O)C(c2ccsc2)(c2cccc(-c3cncnc3)c2)N=C1N +COc1ccc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1C diff --git a/Experiments/BACE/outputs/bace probab.ipynb b/Experiments/BACE/outputs/bace probab.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..071ef5177919c44b661a44a4dd0b1ce2346b8de5 --- /dev/null +++ b/Experiments/BACE/outputs/bace probab.ipynb @@ -0,0 +1,92 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [], + "source": [ + "import pandas as pd" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [], + "source": [ + "df = pd.read_csv('bbbp_fsr_probab.csv')" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "(array([ 1., 0., 0., 0., 2., 2., 2., 2., 6., 3., 10., 5., 7.,\n", + " 12., 10., 12., 4., 8., 8., 6.]),\n", + " array([0.53795552, 0.55553919, 0.57312285, 0.59070652, 0.60829018,\n", + " 0.62587385, 0.64345751, 0.66104118, 0.67862484, 0.69620851,\n", + " 0.71379218, 0.73137584, 0.74895951, 0.76654317, 0.78412684,\n", + " 0.8017105 , 0.81929417, 0.83687783, 0.8544615 , 0.87204516,\n", + " 0.88962883]),\n", + " )" + ] + }, + "execution_count": 4, + "metadata": {}, + "output_type": "execute_result" + }, + { + "data": { + "image/png": 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aW1VrZ2ZmRt2dJGkI4wy/PAN4bpINwBnAoUk+PJGqJEkjGTnUq+r1VbVPVa0BjgbOr6pjJ1aZJGnZ/Jy6JDVk3AOlAFTVBcAFk9iWJGl09tQlqSGGuiQ1xFCXpIYY6pLUEENdkhpiqEtSQwx1SWqIoS5JDTHUJakhhrokNcRQl6SGTOTcL9I08MILkj11SWqKoS5JDTHUJakhhrokNcRQl6SGGOqS1BBDXZIaYqhLUkMMdUlqiKEuSQ0x1CWpIYa6JDXEUJekhowc6kn2TfJPSa5JclWSEydZmCRp+cY59e6PgN+vqkuT7AJckuTcqrp6QrVJkpZp5J56Vd1WVZf2t78HXAPsPanCJEnLN5GLZCRZAzwJuGiBeeuAdQCzs7OT2N3PDC/6IGm5xj5QmmRn4KPAa6rq7vnzq2p9Va2tqrUzMzPj7k6StAVjhXqSB9IF+mlVddZkSpIkjWqcT78E+ABwTVW9a3IlSZJGNU5P/RnAS4BDk1ze/xwxobokSSMY+UBpVX0ByARrkSSNyW+USlJDDHVJaoihLkkNMdQlqSGGuiQ1xFCXpIYY6pLUEENdkhpiqEtSQwx1SWqIoS5JDTHUJakhE7ny0UoY5ypAG04+coKVSNL0sqcuSQ0x1CWpIYa6JDXEUJekhhjqktQQQ12SGmKoS1JDDHVJaoihLkkNMdQlqSGGuiQ1xFCXpIYY6pLUkLFCPcnhSb6W5PokJ02qKEnSaEYO9STbAX8BPAc4ADgmyQGTKkyStHzj9NSfClxfVTdU1X3AGcDzJlOWJGkU41wkY2/g5oH7twC/PH+hJOuAdf3de5J8bYx9Dmt34I6f1PCOFdjj6DapdcpZ69azLdVrrSMYMocWq/cRw+5nnFDPAtNqswlV64H1Y+xn2ZJcXFVrV3Kfo7LWrWNbqhW2rXqtdeuZRL3jDL/cAuw7cH8fYOM4xUiSxjNOqP8L8Jgkj0yyA3A08InJlCVJGsXIwy9V9aMkJwCfBbYDTqmqqyZW2XhWdLhnTNa6dWxLtcK2Va+1bj1j15uqzYbBJUnbKL9RKkkNMdQlqSHbVKgvdVqCJIck+W6Sy/uf/zMwb0OSr/bTL17tWgfqvTzJVUk+t5x1p6zeqWrbJK8deA5cmeTHSR42zLpTVuu0tetDk3wyyRX9c+C4YdedwnqnrW13S/KxJP+a5J+THDjsupupqm3ih+5g7L8BjwJ2AK4ADpi3zCHApxZZfwOw+xTVuitwNTDb399j2HWnqd5pbNt5yx8FnL8abTtOrdPYrsAbgHf0t2eAO/tlp/U5u2C9U9q27wTe0t9+HHDeqM/Zbamnvi2dlmCYWl8EnFVVNwFU1e3LWHea6l1py22fY4DTR1x3NWtdacPUWsAuSQLsTBeSPxpy3Wmqd6UNU+sBwHkAVXUtsCbJnkOuu4ltKdQXOi3B3gssd1D/duszSX5xYHoB5yS5JN2pC7amYWp9LLBbkgv6ml66jHUnbZx6YfraFoAkOwKHAx9d7roTMk6tMH3t+h5gf7ovGX4VOLGq7h9y3Ukbp16Yvra9AngBQJKn0p0WYJ8h193EOKcJWGnDnJbgUuARVXVPkiOAvwce0897RlVtTLIHcG6Sa6vqwlWsdXvgvwKHAQ8GvpzkK0OuO2kj11tVX2f62nbOUcAXq+rOEdadhHFqhelr118DLgcOBR7d1/T5IdedtJHrraq7mb62PRn4sySX070AXUb3rmLZbbst9dSXPC1BVd1dVff0tz8NPDDJ7v39jf3v24GP0b2tWbVa+2X+oarurao7gAuBJwy57qSNU+80tu2co9l0OGOl23acWqexXY+jG4KrqroeuJFu/Hdan7OL1Tt1bdtn13FV9UTgpXTHAG4cZt3NrMSBgkn80PUUbwAeyU8PGPzivGUezk+/UPVU4Ca6V7qdgF366TsBXwIOX+Va96cbQ9se2BG4EjhwmHWnrN6pa9t+uYfSjaHutNx1p6TWqWtX4L3AW/vbewK30p1VcFqfs4vVO41tuys/PYj7SuCvRn3ObrVG30qNcwTwdbqjwW/spx0PHN/fPgG4qn/gXwGe3k9/VD/tin7+G1e71v7+a+k+UXIl8JotrTut9U5x274cOGOYdaex1mlsV2Av4By64YErgWOn+Tm7WL1T2rYHAdcB1wJnAbuN2raeJkCSGrItjalLkpZgqEtSQwx1SWqIoS5JDTHUJakhhrokNcRQl6SG/H/r4BO9qJlXrQAAAABJRU5ErkJggg==", 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" + ] + }, + "metadata": { + "needs_background": "light" + }, + "output_type": "display_data" + } + ], + "source": [ + "import matplotlib.pyplot as plt\n", + "plt.title('Probability Distribution of BBBP')\n", + "plt.hist(df.Probability, bins = 20)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "myenv", + "language": "python", + "name": "myenv" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.8.8" + }, + "orig_nbformat": 4 + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/Experiments/BACE/outputs/bace_gen.txt b/Experiments/BACE/outputs/bace_gen.txt new file mode 100644 index 0000000000000000000000000000000000000000..1485fcd990556ae49500f8bd9a9d2a00b8f1f7bf --- /dev/null +++ b/Experiments/BACE/outputs/bace_gen.txt @@ -0,0 +1,100 @@ +CC(=O)NC(Cc1cc(O)cc(Cl)c1)C(O)C[NH2+]C1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)C4CC(O)C[NH2+]4)cc13)C(=O)OCSC2 +CC1(c2cc(NC(=O)c3ccc(OC(F)(F)F)cn3)ccc2F)N=C(N)OCC1(F)F +CCCCNC(CO)c1cc(CCC)cc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C[NH2+]Cc2cccc(OC)c2)c1 +COc1cccc(C[NH2+]CC(O)C(Cc2ccccc2)NC(=O)C2=CC=CC(Cl)=CC(Cc3cc(F)cc(F)c3)=C2)c1 +CC1(c2cc(NC(=O)c3ccc(OC(F)(F)F)cn3)ccc2F)N=C(N)OCC1(F)F +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)C[NH2+]C1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)C[NH2+]C4CCOCC4)cc13)N(c1cnn(C(C)(C)C)c1)S(=O)(=O)CC2 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)C[NH2+]C4CCOCC4)cc13)N(C)S(=O)(=O)CC2 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)C[NH2+]C1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +CCCN(CCC)C(=O)N(CCC(C)C)C(=O)c1cc(NCC)cc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C[NH2+]Cc2cccc(C(C)C)c2)c1 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+CC(=O)NC(Cc1cc(Cl)cc(Cl)c1)C(O)C[NH2+]C1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)C[NH2+]C1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 diff --git a/Experiments/BACE/outputs/bace_probab.csv b/Experiments/BACE/outputs/bace_probab.csv new file mode 100644 index 0000000000000000000000000000000000000000..a05add4c49ad69ae4305ed59f54c3af3622be001 --- /dev/null +++ b/Experiments/BACE/outputs/bace_probab.csv @@ -0,0 +1,101 @@ +SMILES,Probability +CC(=O)NC(Cc1cc(O)cc(Cl)c1)C(O)C[NH2+]C1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21,0.7752877473831177 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)C4CC(O)C[NH2+]4)cc13)C(=O)OCSC2,0.5637228488922119 +CC1(c2cc(NC(=O)c3ccc(OC(F)(F)F)cn3)ccc2F)N=C(N)OCC1(F)F,0.6324819326400757 +CCCCNC(CO)c1cc(CCC)cc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C[NH2+]Cc2cccc(OC)c2)c1,0.483473539352417 +COc1cccc(C[NH2+]CC(O)C(Cc2ccccc2)NC(=O)C2=CC=CC(Cl)=CC(Cc3cc(F)cc(F)c3)=C2)c1,0.3973110616207123 +CC1(c2cc(NC(=O)c3ccc(OC(F)(F)F)cn3)ccc2F)N=C(N)OCC1(F)F,0.6324819326400757 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"outputs": [], + "source": [ + "import pandas as pd" + ] + }, + { + "cell_type": "code", + "execution_count": 10, + "metadata": {}, + "outputs": [], + "source": [ + "df = pd.read_csv('bace_probab.csv')" + ] + }, + { + "cell_type": "code", + "execution_count": 11, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "(array([ 1., 1., 3., 3., 3., 0., 3., 3., 3., 5., 8., 7., 7.,\n", + " 3., 11., 27., 3., 7., 1., 1.]),\n", + " array([0.3483777 , 0.37580438, 0.40323105, 0.43065773, 0.4580844 ,\n", + " 0.48551108, 0.51293775, 0.54036443, 0.5677911 , 0.59521778,\n", + " 0.62264445, 0.65007113, 0.6774978 , 0.70492448, 0.73235115,\n", + " 0.75977783, 0.7872045 , 0.81463118, 0.84205785, 0.86948453,\n", + " 0.8969112 ]),\n", + " )" + ] + }, + "execution_count": 11, + "metadata": {}, + "output_type": "execute_result" + }, + { + "data": { + "image/png": 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" + ] + }, + "metadata": { + "needs_background": "light" + }, + "output_type": "display_data" + } + ], + "source": [ + "import matplotlib.pyplot as plt\n", + "plt.title('Probability Distribution of BACE')\n", + "plt.hist(df.Probability, bins = 20)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "myenv", + "language": "python", + "name": "myenv" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.8.8" + }, + "orig_nbformat": 4 + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/Experiments/BACE/running utils/base_config.json b/Experiments/BACE/running utils/base_config.json new file mode 100644 index 0000000000000000000000000000000000000000..9d4dfc296e0a9a101aabbde873c4112a906ca3b6 --- /dev/null +++ b/Experiments/BACE/running utils/base_config.json @@ -0,0 +1,23 @@ +{ + "exp_name": "LSTM_Chem", + "data_filename": "/content/medium.txt", + "data_length": 0, + "units": 300, + "num_epochs": 4, + "optimizer": "adam", + "seed": 71, + "batch_size": 128, + "validation_split": 0.1, + "verbose_training": true, + "checkpoint_monitor": "val_loss", + "checkpoint_mode": "min", + "checkpoint_save_best_only": false, + "checkpoint_save_weights_only": true, + "checkpoint_verbose": 1, + "tensorboard_write_graph": true, + "sampling_temp": 0.8, + "smiles_max_length": 128, + "finetune_epochs": 10, + "finetune_batch_size": 1, + "finetune_data_filename": "/content/bace.txt" +} \ No newline at end of file diff --git a/Experiments/BACE/running utils/functions.csv b/Experiments/BACE/running utils/functions.csv new file mode 100644 index 0000000000000000000000000000000000000000..6083018652154fe92e56e4909d0ed2e5428e23ae --- /dev/null +++ b/Experiments/BACE/running utils/functions.csv @@ -0,0 +1,1246 @@ +,Len,Functional grp name,SMARTS,Smiles,Validity +0,7,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +1,8,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O,Valid +2,15,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1,Valid +3,5,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O,Valid +4,8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1,Valid +5,4,Thioesters,[CX3](=[SX1])[SX2],SC=S,Valid +6,13,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl,Valid +7,5,Epoxides,[CX4]1[CX4][OX2]1,C1CO1,Valid +8,12,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +9,13,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC,Valid +10,11,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1,Valid +11,18,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +12,16,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH],Valid +13,18,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1,Valid +14,16,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1,Valid +15,16,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1,Valid +16,14,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH],Valid +17,4,Thiols,[#16X2H1],[SH],Valid +18,7,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH],Valid +19,7,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S,Valid +20,3,Nitroso (general),[NX2]=[OX1],N=O,Valid +21,3,Azo-type (general),[NX2]=[NX2],N=N,Valid +22,5,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O,Valid +23,5,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1,Valid +24,8,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1,Valid +25,4,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N,Valid +26,32,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1,Valid +27,32,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1,Valid +28,11,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O,Valid +29,6,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O,Valid +30,8,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +31,11,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH],Valid +32,7,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +33,5,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O,Valid +34,2,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN,Valid +35,5,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O,Valid +36,6,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC,Valid +37,18,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +38,8,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O,Valid +39,10,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O,Valid +40,11,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O,Valid +41,8,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +42,5,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O,Valid +43,5,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S,Valid +44,18,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +45,7,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl,Valid +46,5,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1,Valid +47,7,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O,Valid +48,10,Primary alkyl amines,[CH2][NH2],[CH2][NH2],Valid +49,18,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3],Valid +50,20,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1,Valid +51,22,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +52,13,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1,Valid +53,19,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21,Valid +54,7,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +55,7,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC,Valid +56,4,Thiocyanates,[SX2][CX2]#[NX1],N#CS,Valid +57,21,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O,Valid +58,12,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +59,6,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O,Valid +60,6,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C,Valid +61,6,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N,Valid +62,12,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C,Valid +63,7,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S,Valid +64,7,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S,Valid +65,2,Peroxides,[OX2][OX2],OO,Valid +66,2,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS,Valid +67,4,Nitroso,[#6][NX2]=[OX1],CN=O,Valid +68,4,N-Nitroso,[#7][NX2]=[OX1],NN=O,Valid +69,5,Azo,[#6][NX2]=[NX2][#6],CN=NC,Valid +70,5,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC,Valid +71,5,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C,Valid +72,6,Hydroxylamines,[OH1][NX3][#6],CN[OH],Valid +73,3,Aminals,N[CX4]N,NCN,Valid +74,12,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C,Valid +75,9,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C,Valid +76,9,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O,Valid +77,9,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O,Valid +78,9,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C,Valid +79,10,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O,Valid +80,6,Acrylonitriles,[NX1]#CC=C,C=CC#N,Valid +81,12,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O,Valid +82,14,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1,Valid +83,5,Ketenes,[CX3]=[CX2]=[OX1],C=C=O,Valid +84,5,Allenes,C=C=C,C=C=C,Valid +85,5,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1,Valid +86,5,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1,Valid +87,5,Aziridines,[CX4]1[NX3][CX4]1,C1CN1,Valid +88,6,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1,Valid +89,6,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1,Valid +90,6,Selen in chain,[Sev2X2],[SeH2],Valid +91,12,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O,Valid +92,12,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N,Valid +93,4,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O,Valid +94,7,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S,Valid +95,7,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S,Valid +96,7,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S,Valid +97,7,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S,Valid +98,11,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O,Valid +99,1,Positively charged N-heterocycles,[#7v4X3R],N,Valid +100,18,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH],Valid +101,20,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1,Valid +102,22,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1,Valid +103,25,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1,Valid +104,27,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1,Valid +105,18,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12,Valid +106,12,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl,Valid +107,12,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O,Valid +108,13,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC,Valid +109,13,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC,Valid +110,9,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O,Valid +111,6,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N,Valid +112,11,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C,Valid +113,10,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O,Valid +114,10,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C,Valid +115,12,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH],Valid +116,12,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C,Valid +117,9,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C,Valid +118,2,Iodine,II,II,Valid +119,8,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H],Valid +120,3,Sulfoxides,[Sv4X3](=[OX1]),O=S,Valid +121,2,Sulfenyl iodides,[SX2][IX1],SI,Valid +122,4,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS,Valid +123,8,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S,Valid +124,8,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS,Valid +125,7,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH],Valid +126,41,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1,Valid +127,5,Organotin compounds,[Sn][#6],C[Sn],Valid +128,8,β-Lactones,C1C(=O)OC1,O=C1CCO1,Valid +129,8,Thio-lactones,C1C(=O)SC1,O=C1CCS1,Valid +130,10,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC,Valid +131,26,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH],Valid +132,14,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1,Valid +133,11,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2],Valid +134,14,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1,Valid +135,11,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1,Valid +136,5,Sulfuranes,C1[SX2]C1,C1CS1,Valid +137,11,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1,Valid +138,12,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O,Valid +139,8,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O,Valid +140,16,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl,Valid +141,17,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C,Valid +142,18,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C,Valid +143,39,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH],Valid +144,19,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH],Valid +145,15,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1,Valid +146,30,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21,Valid +147,11,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O,Valid +148,24,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O,Valid +149,20,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1,Valid +150,7,Furans,c1ccc[oX2]1,c1ccoc1,Valid +151,7,Thiophenes,c1ccc[sX2]1,c1ccsc1,Valid +152,17,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O,Valid +153,10,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH],Valid +154,4,Thioles,[Sv2X2H1],[SH],Valid +155,8,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O,Valid +156,11,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH],Valid +157,1,Phosphorus,P,P,Valid +158,6,Selen,[Se],[SeH2],Valid +159,1,Bor,B,B,Valid +160,6,Silicium,[Si],[SiH4],Valid +161,3,Thione,[CX3]=[SX1!R],C=S,Valid +162,9,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH],Valid +163,7,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S,Valid +164,25,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2],Valid +165,12,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O,Valid +166,16,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1,Valid +167,16,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1,Valid +168,16,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1,Valid +169,16,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1,Valid +170,17,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1,Valid +171,6,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O,Valid +172,6,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N,Valid +173,16,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O,Valid +174,10,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N,Valid +175,12,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S,Valid +176,34,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12,Valid +177,40,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O,Valid +178,16,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH],Valid +179,2,N-N Single bound not in a ring,[N!R][N!R],NN,Valid +180,11,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC,Valid +181,10,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O,Valid +182,12,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1,Valid +183,15,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O,Valid +184,18,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3,Valid +185,18,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3,Valid +186,21,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1,Valid +187,18,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23,Valid +188,6,Cyano carbonyl compounds ,N#CC(=O),N#CC=O,Valid +189,5,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N,Valid +190,6,Benzyl ammoniums,cC[NX4+],cC[N+],Valid +191,8,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O,Valid +192,9,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N,Valid +193,7,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O,Valid +194,3,Singel acyclic N-N bonds,[#7]!@-N,N~N,Valid +195,11,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N,Valid +196,7,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O,Valid +197,2,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS,Valid +198,8,Phosphonates,[#6]P(=O)O[#6],COP(C)=O,Valid +199,16,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +200,14,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O,Valid +201,4,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS,Valid +202,13,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O,Valid +203,11,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F,Valid +204,4,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O,Valid +205,20,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1,Valid +206,15,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1,Valid +207,3,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC,Valid +208,4,Phosphocyanates,PC#N,N#CP,Valid +209,8,α-Hydroxy nitriles,N#CC[OH],N#CC[OH],Valid +210,6,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O,Valid +211,2,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO,Valid +212,11,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N,Valid +213,3,Nitroso compounds,[NX2]=O,N=O,Valid +214,19,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F,Valid +215,22,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +216,17,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1,Valid +217,1,Phosphorus derivatives,[P!v5],P,Valid +218,12,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C,Valid +219,22,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1,Valid +220,18,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1,Valid +221,17,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1,Valid +222,17,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1,Valid +223,7,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O,Valid +224,15,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O,Valid +225,14,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1,Valid +226,6,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC,Valid +227,16,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH],Valid +228,18,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1,Valid +229,20,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21,Valid +230,14,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH],Valid +231,17,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1,Valid +232,15,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21,Valid +233,6,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c,Valid +234,11,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N,Valid +235,6,Phosphorus cations,[#15+],[PH4+],Valid +236,10,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O,Valid +237,3,Double P=O bonds,[#15]=O,O=P,Valid +238,5,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH],Valid +239,7,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +240,3,Nitrosos,[NX2]=[OX1],N=O,Valid +241,10,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F,Valid +242,7,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S,Valid +243,5,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH],Valid +244,12,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH],Valid +245,12,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH],Valid +246,5,Phenols,c[OH1],c[OH],Valid +247,3,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC,Valid +248,3,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc,Valid +249,3,Diarylethers,c[OX2&!$([OX2r3])]c,cOc,Valid +250,6,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid +251,6,Primary aromatic amines,[NX3H2]c,c[NH2],Valid +252,6,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C,Valid +253,6,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C,Valid +254,6,Secondary aromatic amines,[NX3H1](c)c,c[NH]c,Valid +255,6,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C,Valid +256,5,Organolithium compounds,[Li][#6],[Li]C,Valid +257,5,Organomagnesium compounds,[Mg][#6],C[Mg],Valid +258,7,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O,Valid +259,10,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O,Valid +260,7,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O,Valid +261,11,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH],Valid +262,9,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC,Valid +263,10,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH],Valid +264,13,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC,Valid +265,12,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O,Valid +266,11,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O,Valid +267,8,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O,Valid +268,7,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O,Valid +269,6,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH],Valid +270,4,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC,Valid +271,7,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C,Valid +272,5,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH],Valid +273,5,Thiophenols,c[Sv2H1],c[SH],Valid +274,13,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH],Valid +275,13,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH],Valid +276,6,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C,Valid +277,10,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O,Valid +278,12,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH],Valid +279,6,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C,Valid +280,7,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C,Valid +281,7,Alkynyl alcohols,[CX2]#[CX2][OH1],C#C[OH],Valid +282,7,Alkynyl thiols,[CX2]#[CX2][SH1],C#C[SH],Valid +283,21,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O,NC(COP(O)(O)=O)C(O)=O,Valid +284,24,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O,CC(OP(O)(O)=O)C(N)C(O)=O,Valid +285,31,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,Valid +286,10,sulphonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +287,14,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S,O=C(S)C(F)(F)F,Valid +288,5,hydroxamate_warhead,C([N;H1]([O;D1]))=O,ONC=O,Valid +289,12,thiol_warhead,NC(C[S;D1])C(O)=O,NC(CS)C(O)=O,Valid +290,6,acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +291,25,pentafluorophenylester,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +292,10,acyl_imidazole,"[C;!$(C-N)](=O)n1[c;H1,$([#6]([*;!R]))]n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1ccnc1,Valid +293,16,ortho_hydroiminoquinone,c1c([N;D1])c([N;D1])c[cH1][cH1]1,Nc1c[cH][cH]cc1N,Valid +294,3,phosphorus_phosphorus_bond,P~P,P~P,Valid +295,10,acyl_pyrazole,"[C;!$(C-N)](=O)n1n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1cccn1,Valid +296,12,acyl_123_triazole,"[#7;R1]1=,:[#7;R1]-,:[#7;R1](-C(=O))-,:[#6]=,:[#6]1",O=CN1C=CN=N1,Valid +297,7,alpha_dicarbonyl,C(=O)!@C(=O),O=C~C=O,Valid +298,14,trifluoroacetate_ester,C(F)(F)(F)C(=O)O,OC(=O)C(F)(F)F,Valid +299,2,sulf_D2_nitrogen,[S;D2](-[N;!$(N(=C));!$(N(-S(=O)(=O)));!$(N(-C(=O)))]),NS,Valid +300,18,triflate,OS(=O)(=O)(C(F)(F)(F)),OS(=O)(=O)C(F)(F)F,Valid +301,15,rhodanine,C(=C)1SC(=S)NC(=O)1,C=C1SC(=S)NC1=O,Valid +302,5,NO_phosphonate,P(=O)ON,NOP=O,Valid +303,3,azo_filter3,[N;!R]-[N;!R]-[N;!R],NNN,Valid +304,30,disulfonyliminoquinone,S(=O)(=O)N=C1C=CC(=NS(=O)(=O))C=C1,O=S(=O)N=C1C=CC(=NS(=O)=O)C=C1,Valid +305,28,perchloro_cp,C1(Cl)(Cl)C(Cl)C(Cl)=C(Cl)C1(Cl),ClC1C(Cl)=C(Cl)C(Cl)C1(Cl)Cl,Valid +306,20,meldrums_acid_deriv,O=C1OC(C)(C)OC(C1)=O,CC1(C)OC(=O)CC(=O)O1,Valid +307,2,sulf_D2_oxygen_D2,[S;D2][O;D2],OS,Valid +308,3,azo_filter2,[N;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!r3;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!$(N-S(=O)(=O));!$(N-C=O)],NNN,Valid +309,2,hydrazine,[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))]-[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))],NN,Valid +310,10,isonitrile,[N+]#[C-],[C-]#[NH+],Valid +311,14,gte_3_COOH,C(=O)[O;D1].C(=O)[O;D1].C(=O)[O;D1],OC=O.OC=O.OC=O,Valid +312,3,phosphorus_sulfur_bond,P~S,P~S,Valid +313,9,polyene,C=[C;!R][C;!R]=[C;!R][C;!R]=[C;!R],C=CC=CC=C,Valid +314,4,azo_amino,[N]=[N;!R]-[N],N=NN,Valid +315,7,nitrone,[C;!R]=[N+][O;D1],C=[N+]O,Valid +316,1,sulfonium,[S+;X3;$(S-C);!$(S-[O;D1])],S,Valid +317,3,polysulfide,[S;D2]-[S;D2]-[S;D2],SSS,Valid +318,6,acrylate,[CH2]=[C;!$(C-N);!$(C-O)]C(=O),C=CC=O,Valid +319,15,four_nitriles,C#N.C#N.C#N.C#N,C#N.C#N.C#N.C#N,Valid +320,3,phosphorane,C=P,C=P,Valid +321,20,gte_7_aliphatic_OH,C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1],CO.CO.CO.CO.CO.CO.CO,Valid +322,9,gte_2_free_phos,P([O;D1])=O.P([O;D1])=O,OP=O.OP=O,Valid +323,22,benzidine_like,c([N;!+])1ccc(c2ccc([N;!+])cc2)cc1,Nc1ccc(c2ccc(N)cc2)cc1,Valid +324,9,hydrazothiourea,[N;!R]=NC(=S)N,NC(=S)N=N,Valid +325,4,nitrosamine,N-[N;X2](=O),NN=O,Valid +326,10,gte_10_carbon_sb_chain,[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R],CCCCCCCCCC,Valid +327,10,betalactam,C1(=O)~[#6]~[#6]N1,O=C1NC~C~1,Valid +328,3,peroxide,[#8]~[#8],O~O,Valid +329,18,paraquat_like,[#6]1[#6][#6]([#6]2[#6][#6][#7;+][#6][#6]2)[#6][#6][#7;+]1,C1CC(C2CCNCC2)CCN1,Valid +330,5,azo_aryl,c[N;!R;!+]=[N;!R;!+]-c,cN=Nc,Valid +331,2,disulfide_acyclic,[S;!R;X2]-[S;!R;X2],SS,Valid +332,5,gte_3_iodine,[#53].[#53].[#53],I.I.I,Valid +333,17,porphyrin,"[#6;r16,r17,r18]~[#6]1~[#6]~[#6]~[#6](~[#6])~[#7]1",C~C1N~C(~C)~C~C~1,Valid +334,7,thio_xanthate,[S;!R]-[C;!R](=[S;!R])(-[S;!R]),S=C(S)S,Valid +335,13,double_trouble_warhead,NC(C[S;D1])C([N;H1]([O;D1]))=O,NC(CS)C(=O)NO,Valid +336,13,Hzone_phenol_A,c1ccc(c(c1)[#8!H0])[#6]=[#7][#7],NN=Cc1ccccc1O,Valid +337,3,Azo_A,[N!R]=N,N=N,Valid +338,14,Mannich_A,N[CX4]c1c([OH1])cccc1,NCc1ccccc1[OH],Valid +339,15,Ene_rhod_A,N1C(=S)SC(=C)C1=O,C=C1SC(=S)NC1=O,Valid +340,18,Hzone_phenol_B,c1(ccc(cc1)C=N[#7])[OH1],NN=Cc1ccc([OH])cc1,Valid +341,20,Imine_one_isatin,[OX1]=C2C(=;!@N[#7])c3c(cccc3)N2,NN=C1C(=O)Nc2ccccc21,Valid +342,18,Anil_di_alk_B,c1c(ccc(c1)[#6]=[#6])[#7]([CX4])[CX4],CN(C)c1ccc(C=C)cc1,Valid +343,16,Catechol_A,c1ccc(c(c1)[OH1])[OH1],[OH]c1ccccc1[OH],Valid +344,21,Ene_five_one_A,c2ccc1C(=[OX1])C(=C)C(=[OX1])c1c2,C=C1C(=O)c2ccccc2C1=O,Valid +345,12,Ene_five_het_B,C1(=C)C(N=CS1)=O,C=C1SC=NC1=O,Valid +346,15,Ene_five_het_D,C1(=C)C(=[OX1])NNC1=[OX1],C=C1C(=O)NNC1=O,Valid +347,27,Ene_five_het_F,c1(ccccc1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)S2,O=C1C(=Cc2ccccc2)Sc2ccccc21,Valid +348,20,Ene_one_ester,[#6][#6](=[#8])[#6!H0]=[#6]([#7!H0][#6])[#6](=[#8])[#8][#6],CNC(=CC(C)=O)C(=O)OC,Valid +349,18,Ene_one_D,c([OH1])c-C(=[OX1])[C!H0]=C([#6])[#6],CC(C)=CC(=O)cc[OH],Valid +350,19,Ene_cyano_A,[#6](C#[#7])(C#[#7])=Cc1ccccc1,N#CC(=Cc1ccccc1)C#N,Valid +351,21,Hzone_pyrrol,n1(C)[cH1][cH1][cH1]c1C=NN,Cn1[cH][cH][cH]c1C=NN,Valid +352,45,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2,C=NNC(=O)c1[cH]c2[cH][cH][cH][cH]c2[cH]c1[OH],Valid +353,19,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1,O=C1CC(=O)c2ccccc21,Valid +354,22,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1],N#CC=C([NH2])C(C#N)C#N,Valid +355,20,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1,N#CC(C#N)=NNc1ccccc1,Valid +356,20,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9,C1C=CC2C1CNc1ccccc12,Valid +357,21,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7],Nc1c2ccccc2nc2ccccc12,Valid +358,13,Thiophene_hydroxy,"[#16]1-,:[#6]=,:[#6]-,:[#6](=,:[#6]1)[OH1]",[OH]C1=CSC=C1,Valid +359,25,Sulfonamide_B,c1c(ccc(c1)[NH]S(=[OX1])=[OX1])[OH1],O=S(=O)[NH]c1ccc([OH])cc1,Valid +360,7,Thio_ketone,"[#6]-,:[CX3](=[SX1])-,:[#6]",CC(C)=S,Valid +361,13,Rhod_sat_A,"[#7]1-,:[#6](=[#16])-,:[#16]-,:[#6X4]-,:[#6]1=[#8]",O=C1CSC(=S)N1,Valid +362,20,Imine_one_sixes,C1(C(=[OX1])NC(=[OX1])NC1(=[OX1]))=N,N=C1C(=O)NC(=O)NC1=O,Valid +363,22,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1,Valid +364,21,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1,Valid +365,21,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH],Valid +366,34,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +367,46,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH],Valid +368,31,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH],Valid +369,31,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1,Valid +370,51,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1,Valid +371,25,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH],Valid +372,36,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1,Valid +373,14,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1,Valid +374,27,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2,Valid +375,72,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1,Valid +376,39,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12,Valid +377,24,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC,Valid +378,27,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1,Valid +379,40,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1,Valid +380,32,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH],Valid +381,45,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12,Valid +382,38,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1,Valid +383,21,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2],Valid +384,39,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1,Valid +385,27,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12,Valid +386,31,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1,Valid +387,34,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12,Valid +388,52,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1,Valid +389,25,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1,Valid +390,30,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1,Valid +391,18,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1,Valid +392,46,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1,Valid +393,18,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1,Valid +394,22,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1,Valid +395,34,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2,Valid +396,18,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1,Valid +397,46,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +398,39,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1,Valid +399,32,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1,Valid +400,34,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12,Valid +401,17,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1,Valid +402,29,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O,Valid +403,21,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12,Valid +404,29,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21,Valid +405,48,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1,Valid +406,48,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1,Valid +407,22,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1,Valid +408,38,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc,Valid +409,34,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1,Valid +410,45,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1,Valid +411,19,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3,Valid +412,33,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21,Valid +413,22,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21,Valid +414,28,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12,Valid +415,18,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1,Valid +416,14,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1,Valid +417,20,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc,Valid +418,13,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1,Valid +419,26,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1,Valid +420,42,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1,Valid +421,18,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1,Valid +422,41,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21,Valid +423,48,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12,Valid +424,52,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21,Valid +425,10,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1,Valid +426,22,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1,Valid +427,16,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2,Valid +428,19,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc,Valid +429,44,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1,Valid +430,24,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21,Valid +431,26,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2,Valid +432,29,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21,Valid +433,30,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc,Valid +434,33,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21,Valid +435,15,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN,Valid +436,15,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S,Valid +437,12,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N,Valid +438,65,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1,Valid +439,25,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1,Valid +440,12,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S,Valid +441,23,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S,Valid +442,24,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1,Valid +443,47,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1,Valid +444,16,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O,Valid +445,17,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S,Valid +446,15,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1,Valid +447,41,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O,Valid +448,19,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1,Valid +449,31,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N,Valid +450,28,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21,Valid +451,21,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N,Valid +452,39,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2],Valid +453,48,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1,Valid +454,19,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N,Valid +455,27,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N,Valid +456,24,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc,Valid +457,16,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O,Valid +458,14,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O,Valid +459,19,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O,Valid +460,22,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12,Valid +461,23,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc,Valid +462,25,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1,Valid +463,15,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C,Valid +464,15,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1,Valid +465,18,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1,Valid +466,29,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O,Valid +467,33,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1,Valid +468,24,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1,Valid +469,28,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1,Valid +470,10,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1,Valid +471,22,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1,Valid +472,26,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1,Valid +473,25,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1,Valid +474,18,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S,Valid +475,18,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12,Valid +476,44,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1,Valid +477,52,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1,Valid +478,19,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2,Valid +479,22,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1,Valid +480,11,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1,Valid +481,22,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N,Valid +482,20,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12,Valid +483,27,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C,Valid +484,30,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N,Valid +485,28,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1,Valid +486,32,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH],Valid +487,23,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc,Valid +488,33,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12,Valid +489,35,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1,Valid +490,13,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1,Valid +491,20,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O,Valid +492,10,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH],Valid +493,27,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O,Valid +494,20,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21,Valid +495,20,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1,Valid +496,50,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21,Valid +497,42,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21,Valid +498,33,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1,Valid +499,13,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O,Valid +500,22,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O,Valid +501,21,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1,Valid +502,30,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O,Valid +503,11,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C,Valid +504,20,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1,Valid +505,20,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1,Valid +506,16,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21,Valid +507,11,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C,Valid +508,17,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O,Valid +509,15,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH],Valid +510,22,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S,Valid +511,24,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1,Valid +512,34,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1,Valid +513,32,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21,Valid +514,36,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O,Valid +515,24,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1,Valid +516,15,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1,Valid +517,29,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2],Valid +518,40,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1,Valid +519,26,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1,Valid +520,15,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc,Valid +521,25,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1,Valid +522,54,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1,Valid +523,34,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1,Valid +524,22,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc,Valid +525,12,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1,Valid +526,24,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1,Valid +527,24,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O,Valid +528,26,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1,Valid +529,18,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1,Valid +530,46,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1,Valid +531,26,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1,Valid +532,26,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3,Valid +533,25,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1,Valid +534,16,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N,Valid +535,28,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1,Valid +536,36,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O,Valid +537,38,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1,Valid +538,25,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1,Valid +539,38,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1,Valid +540,72,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2,Valid +541,56,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1,Valid +542,40,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1,Valid +543,20,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23,Valid +544,22,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2,Valid +545,35,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F,Valid +546,27,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2,Valid +547,35,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O,Valid +548,21,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1,Valid +549,38,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1,Valid +550,28,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1,Valid +551,32,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O,Valid +552,36,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1,Valid +553,29,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O,Valid +554,32,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O,Valid +555,61,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1,Valid +556,87,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH],Valid +557,27,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH],Valid +558,57,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1,Valid +559,59,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3],Valid +560,49,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1,Valid +561,49,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1,Valid +562,40,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH],Valid +563,23,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH],Valid +564,35,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1,Valid +565,39,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1,Valid +566,25,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1,Valid +567,81,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1,Valid +568,22,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1,Valid +569,31,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH],Valid +570,5,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1,Valid +571,5,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1,Valid +572,5,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1,Valid +573,6,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1,Valid +574,6,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1,Valid +575,6,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1,Valid +576,6,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1,Valid +577,5,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1,Valid +578,5,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1,Valid +579,5,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1,Valid +580,5,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1,Valid +581,6,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1,Valid +582,6,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1,Valid +583,6,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1,Valid +584,6,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1,Valid +585,5,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1,Valid +586,5,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1,Valid +587,5,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1,Valid +588,5,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1,Valid +589,5,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1,Valid +590,5,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1,Valid +591,5,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1,Valid +592,6,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1,Valid +593,6,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1,Valid +594,6,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1,Valid +595,6,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1,Valid +596,6,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1,Valid +597,6,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1,Valid +598,7,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1,Valid +599,7,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1,Valid +600,8,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1,Valid +601,7,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1,Valid +602,7,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1,Valid +603,6,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1,Valid +604,6,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1,Valid +605,6,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1,Valid +606,6,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1,Valid +607,6,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1,Valid +608,6,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1,Valid +609,7,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1,Valid +610,7,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1,Valid +611,7,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1,Valid +612,7,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1,Valid +613,7,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1,Valid +614,8,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1,Valid +615,8,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1,Valid +616,8,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1,Valid +617,8,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1,Valid +618,8,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1,Valid +619,8,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1,Valid +620,8,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1,Valid +621,7,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1,Valid +622,7,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1,Valid +623,7,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1,Valid +624,13,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1,Valid +625,13,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1,Valid +626,13,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1,Valid +627,7,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1,Valid +628,7,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1,Valid +629,7,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1,Valid +630,7,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1,Valid +631,7,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1,Valid +632,7,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1,Valid +633,8,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1,Valid +634,8,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1,Valid +635,8,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1,Valid +636,8,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1,Valid +637,8,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1,Valid +638,8,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1,Valid +639,8,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1,Valid +640,8,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1,Valid +641,8,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1,Valid +642,7,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1,Valid +643,7,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1,Valid +644,7,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1,Valid +645,7,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1,Valid +646,7,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1,Valid +647,7,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1,Valid +648,7,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1,Valid +649,7,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1,Valid +650,7,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1,Valid +651,7,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1,Valid +652,7,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1,Valid +653,7,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1,Valid +654,8,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1,Valid +655,8,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1,Valid +656,7,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1,Valid +657,7,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1,Valid +658,7,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1,Valid +659,7,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1,Valid +660,7,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1,Valid +661,7,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1,Valid +662,7,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1,Valid +663,7,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1,Valid +664,7,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1,Valid +665,7,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1,Valid +666,7,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1,Valid +667,7,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1,Valid +668,7,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1,Valid +669,7,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1,Valid +670,7,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1,Valid +671,7,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1,Valid +672,7,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1,Valid +673,7,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1,Valid +674,8,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1,Valid +675,8,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1,Valid +676,8,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1,Valid +677,9,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1,Valid +678,9,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1,Valid +679,8,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1,Valid +680,8,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1,Valid +681,8,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1,Valid +682,8,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1,Valid +683,8,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1,Valid +684,8,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1,Valid +685,8,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1,Valid +686,8,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1,Valid +687,8,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1,Valid +688,5,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C,Valid +689,5,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF,Valid +690,6,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl,Valid +691,6,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr,Valid +692,5,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI,Valid +693,4,Vinyl fluorides,F[CX3]=[CX3],C=CF,Valid +694,5,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl,Valid +695,5,Vinyl bromides,Br[CX3]=[CX3],C=CBr,Valid +696,4,Vinyl iodides,I[CX3]=[CX3],C=CI,Valid +697,4,Alkynyl fluorides,F[CX2]#[CX2],C#CF,Valid +698,5,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl,Valid +699,4,Alkynyl iodides,I[CX2]#[CX2],C#CI,Valid +700,5,Alkynyl bromides,Br[CX2]#[CX2],C#CBr,Valid +701,3,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC,Valid +702,3,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc,Valid +703,3,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc,Valid +704,10,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH],Valid +705,10,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH],Valid +706,5,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C,Valid +707,5,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C,Valid +708,7,Aldehyde,[CX3H1](=O)[#6],C[CH]=O,Valid +709,3,Formaldehyde,[CX3H2](=O),C=O,Valid +710,7,Ketone,[C][C](=O)[C],CC(C)=O,Valid +711,3,Nitrile,[C]#[N],C#N,Valid +712,27,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1,Valid +713,42,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1,Valid +714,19,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21,Valid +715,17,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21,Valid +716,14,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1,Valid +717,10,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1,Valid +718,14,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n,Valid +719,21,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12,Valid +720,21,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1,Valid +721,16,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1,Valid +722,10,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn,Valid +723,17,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1,Valid +724,18,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1,Valid +725,18,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12,Valid +726,18,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12,Valid +727,23,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12,Valid +728,26,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1,Valid +729,18,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1,Valid +730,18,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1,Valid +731,26,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1,Valid +732,18,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1,Valid +733,25,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1,Valid +734,21,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1,Valid +735,21,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12,Valid +736,18,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12,Valid +737,16,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH],Valid +738,16,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S,Valid +739,16,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH],Valid +740,16,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH],Valid +741,16,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S,Valid +742,22,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C,Valid +743,16,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH],Valid +744,22,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C,Valid +745,23,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S,Valid +746,19,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S,Valid +747,21,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH],Valid +748,22,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH],Valid +749,14,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH],Valid +750,11,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH],Valid +751,19,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1,Valid +752,16,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1,Valid +753,24,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1,Valid +754,21,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1,Valid +755,20,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1,Valid +756,11,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1,Valid +757,27,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21,Valid +758,30,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1,Valid +759,22,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12,Valid +760,16,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH],Valid +761,18,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH],Valid +762,22,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH],Valid +763,22,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH],Valid +764,28,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH],Valid +765,27,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH],Valid +766,25,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1,Valid +767,25,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1,Valid +768,29,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1,Valid +769,25,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1,Valid +770,13,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O,Valid +771,4,Pt,[Pt],[Pt],Valid +772,7,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +773,9,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O,Valid +774,34,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +775,28,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1,Valid +776,51,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1,Valid +777,46,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +778,33,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1,Valid +779,36,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21,Valid +780,11,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1,Valid +781,32,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12,Valid +782,35,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1,Valid +783,18,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH],Valid +784,21,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1,Valid +785,32,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1,Valid +786,19,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12,Valid +787,1,Radical,[#16;X3v3+0],S,Valid +788,4,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +789,9,6 - Methanol,[CX4H3][OX2H1],[CH3][OH],Valid +790,1,7 - Water,[OX2H2],O,Valid +791,7,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O,Valid +792,8,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +793,13,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +794,5,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S,Valid +795,15,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +796,18,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +797,1,32 - Iodo compounds,[I],I,Valid +798,2,33 - Bromo compounds,[Br!$([Br][cR])],Br,Valid +799,15,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +800,9,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +801,5,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl,Valid +802,8,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +803,26,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +804,27,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +805,7,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +806,6,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C,Valid +807,9,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH],Valid +808,3,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C,Valid +809,6,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C,Valid +810,3,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C,Valid +811,5,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c,Valid +812,4,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +813,9,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH],Valid +814,1,17 - H2O (7 - Water),[OX2H2],O,Valid +815,11,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O,Valid +816,11,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O,Valid +817,7,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O,Valid +818,12,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O,Valid +819,12,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O,Valid +820,8,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +821,7,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3],Valid +822,7,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2],Valid +823,10,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2],Valid +824,10,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2],Valid +825,9,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2],Valid +826,10,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3],Valid +827,10,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2],Valid +828,9,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH],Valid +829,10,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3],Valid +830,10,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2],Valid +831,23,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1,Valid +832,8,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N,Valid +833,8,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N,Valid +834,7,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH],Valid +835,10,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH],Valid +836,7,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl,Valid +837,9,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl,Valid +838,12,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl,Valid +839,13,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +840,5,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S,Valid +841,9,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH],Valid +842,9,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH],Valid +843,15,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +844,18,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +845,1,64 - I (32 - Iodo compounds),[I],I,Valid +846,2,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br,Valid +847,3,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C,Valid +848,3,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C,Valid +849,15,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +850,9,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +851,5,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl,Valid +852,19,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O,Valid +853,19,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O,Valid +854,8,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +855,6,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3],Valid +856,7,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2],Valid +857,6,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH],Valid +858,5,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si],Valid +859,26,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +860,12,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl,Valid +861,11,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl,Valid +862,10,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl,Valid +863,10,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl,Valid +864,11,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl,Valid +865,8,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O,Valid +866,12,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O,Valid +867,12,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O,Valid +868,16,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O,Valid +869,16,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O,Valid +870,16,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O,Valid +871,15,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH],Valid +872,27,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +873,21,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1,Valid +874,19,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O,Valid +875,18,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O,Valid +876,13,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1,Valid +877,12,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1,Valid +878,9,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1,Valid +879,11,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1,Valid +880,8,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1,Valid +881,5,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1,Valid +882,7,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +883,10,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O,Valid +884,11,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C,Valid +885,35,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1,Valid +886,11,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1,Valid +887,18,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1,Valid +888,14,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O,Valid +889,7,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O,Valid +890,2,R7 - Peroxides,OO,OO,Valid +891,25,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +892,21,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1,Valid +893,7,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O,Valid +894,18,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +895,7,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S,Valid +896,10,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +897,12,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-],Valid +898,5,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O,Valid +899,3,R19 - Phosphoranes,C=P,C=P,Valid +900,8,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +901,3,R21 - Nitroso,[N&D2](=O),N=O,Valid +902,5,R23 - Carbodiumide,N=C=N,N=C=N,Valid +903,10,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +904,13,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +905,8,R26 - Cyanohydrins,N#CC[OH],N#CC[OH],Valid +906,6,R27 - Acyl cyanides,N#CC(=O),N#CC=O,Valid +907,10,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O,Valid +908,16,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +909,6,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N,Valid +910,7,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +911,7,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC,Valid +912,7,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +913,2,I4 - Disulphides,SS,SS,Valid +914,4,I5 - Thiols,[SH],[SH],Valid +915,17,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +916,18,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +917,9,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +918,4,I10 - Thiocyanate,SC#N,N#CS,Valid +919,6,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+],Valid +920,9,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N,Valid +921,8,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1,Valid +922,19,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +923,8,I16 - Betalactams,N1CCC1=O,O=C1CCN1,Valid +924,16,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1,Valid +925,12,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +926,25,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +927,15,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +928,14,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +929,17,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +930,55,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1,Valid +931,14,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +932,13,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1,Valid +933,13,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1,Valid +934,20,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1,Valid +935,17,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O,Valid +936,12,A8,[nH1]1ncoc1=O,O=c1[nH]nco1,Valid +937,13,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1,Valid +938,15,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1,Valid +939,16,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1,Valid +940,13,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1,Valid +941,12,A13,[nH1]1occc1=O,O=c1cco[nH]1,Valid +942,11,A14,[OH1]c1oncc1,[OH]c1ccno1,Valid +943,12,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1,Valid +944,7,A16 - tetrazole,[nH1]nnn,nnn[nH],Valid +945,7,A17,[nH1](n)nn,nn[nH]n,Valid +946,16,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1,Valid +947,16,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1,Valid +948,18,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1,Valid +949,18,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1,Valid +950,16,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1,Valid +951,16,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1,Valid +952,16,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1,Valid +953,26,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21,Valid +954,26,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21,Valid +955,22,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21,Valid +956,16,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH],Valid +957,13,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1,Valid +958,8,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH],Valid +959,21,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F,Valid +960,12,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O,Valid +961,6,B1 - primary amine,[NH2][CX4],C[NH2],Valid +962,6,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C,Valid +963,6,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C,Valid +964,8,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1,Valid +965,7,E4EXC,C(=O)[OH1],O=C[OH],Valid +966,7,E5EXC,C(=O)[SH1],O=C[SH],Valid +967,5,E9EXC,P[OH1],[OH]P,Valid +968,9,E11,c(=O)(~c)~c,c~c(~c)=O,Valid +969,7,E13 - imides,C(=O)-N-C=O,O=CNC=O,Valid +970,6,N1 - pimary amines,[NX3H2][CX4],C[NH2],Valid +971,6,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C,Valid +972,7,N7EXC,[OH1]C=C,C=C[OH],Valid +973,4,Acyclic C=C-O,C=[C!r]O,C=CO,Valid +974,6,Acyl cyanide,N#CC(=O),N#CC=O,Valid +975,9,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O,Valid +976,13,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1,Valid +977,33,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1,Valid +978,11,Azido group,N=[N+]=[N-],[N-]=[N+]=N,Valid +979,3,Azo group,N=N,N=N,Valid +980,38,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1,Valid +981,14,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +982,6,Conjugated nitrile group,C=[C!r]C#N,C=CC#N,Valid +983,16,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1,Valid +984,9,Cyanamide,N[CH2]C#N,N[CH2]C#N,Valid +985,8,Cyanohydrins,N#CC[OH],N#CC[OH],Valid +986,9,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1,Valid +987,9,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1,Valid +988,10,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1,Valid +989,10,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1,Valid +990,3,Diazo group,[N!R]=[N!R],N=N,Valid +991,2,Disulphide,SS,SS,Valid +992,2,Enamine,[CX3R0][NX3R0],CN,Valid +993,7,Ester of HOBT,C(=O)Onnn,nnnOC=O,Valid +994,8,Four member lactones,C1(=O)OCC1,O=C1CCO1,Valid +995,13,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1,Valid +996,8,Hydroxamic acid,C(=O)N[OH],O=CN[OH],Valid +997,3,Imine,C=[N!R],C=N,Valid +998,5,Ketene,C=C=O,C=C=O,Valid +999,10,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1,Valid +1000,11,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O,Valid +1001,14,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1,Valid +1002,5,N-hydroxylpyridine,n[OH],n[OH],Valid +1003,4,N-nitroso,[#7]-N=O,NN=O,Valid +1004,10,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F,Valid +1005,2,Peroxide,OO,OO,Valid +1006,15,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1,Valid +1007,15,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1,Valid +1008,1,Phosphor,P,P,Valid +1009,6,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C,Valid +1010,25,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1011,21,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1,Valid +1012,10,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1013,2,Sulfur oxygen single bond,[SX2]O,OS,Valid +1014,14,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-],Valid +1015,2,Sulphur nitrogen single bond,[SX2H0][N],NS,Valid +1016,15,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1,Valid +1017,15,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1,Valid +1018,5,Thiol (1),[S-],[SH-],Valid +1019,4,Thiol (2),[SH],[SH],Valid +1020,18,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +1021,3,Triple bond,C#C,C#C,Valid +1022,5,Deuterium,[2H],[2HH],Valid +1023,7,C13,[13#6],[13CH4],Valid +1024,10,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1,Valid +1025,23,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O,Valid +1026,2,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN,Valid +1027,3,Acyclic N-C-N,N-!@[CX4]-!@N,NCN,Valid +1028,6,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O,Valid +1029,27,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O,Valid +1030,20,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1,Valid +1031,7,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O,Valid +1032,9,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N,Valid +1033,7,26,N-C(=S)-N,NC(N)=S,Valid +1034,4,Thio cyanates,S-C#N,N#CS,Valid +1035,11,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O,Valid +1036,12,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2],Valid +1037,30,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2],Valid +1038,3,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N,Valid +1039,2,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO,Valid +1040,2,42,S-S,SS,Valid +1041,3,43,O~O,O~O,Valid +1042,18,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3,Valid +1043,7,Too many cyano groups (>1),C#N.C#N,C#N.C#N,Valid +1044,15,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH],Valid +1045,12,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O,Valid +1046,4,Chlorates,Cl~O,O~Cl,Valid +1047,5,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O,Valid +1048,6,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C,Valid +1049,2,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN,Valid +1050,8,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH],Valid +1051,14,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O,Valid +1052,50,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3],Valid +1053,2,Filter35_PP_bond,P-P,PP,Valid +1054,3,Filter36_SS_double_bond,S=S,S=S,Valid +1055,8,Filter37_silicate,[Si]~O,O~[SiH4],Valid +1056,6,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O,Valid +1057,6,Filter51_PN3,N[PX3](N)N,NP(N)N,Valid +1058,16,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +1059,2,Filter56_SS_bond,S-S,SS,Valid +1060,15,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1,Valid +1061,15,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1,Valid +1062,3,Filter59_phoshorous_ylide,C=P,C=P,Valid +1063,3,Filter60_Acyclic_N-S,N!@[SX2],N~S,Valid +1064,24,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F,Valid +1065,14,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH],Valid +1066,7,Filter73_thio_ketone,CC(=S)C,CC(C)=S,Valid +1067,7,Filter76_S_ester,CC(=S)O,CC(O)=S,Valid +1068,20,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1,Valid +1069,4,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N,Valid +1070,3,Filter90_N_double_bond_S,N=!@S,N=S,Valid +1071,12,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O,Valid +1072,7,Anhydride,C(=O)OC(=O),O=COC=O,Valid +1073,26,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1,Valid +1074,7,HOBT ester,C(=O)Onnn,nnnOC=O,Valid +1075,12,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-],Valid +1076,6,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N,Valid +1077,8,Cyanohydrin,N#CC[OH],N#CC[OH],Valid +1078,8,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +1079,13,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +1080,6,Benzylic quaternary nitrogen,cC[N+],cC[N+],Valid +1081,3,Phosphorane,C=P,C=P,Valid +1082,7,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S,Valid +1083,16,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +1084,4,Thiol,[SH],[SH],Valid +1085,20,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1,Valid +1086,18,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +1087,17,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1088,18,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1089,7,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1090,9,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +1091,13,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH],Valid +1092,8,Ester,[#6]-C(=O)O-[#6],COC(C)=O,Valid +1093,3,Imine 3,C=[NH],C=N,Valid +1094,7,Thioketone,CC(=S)C,CC(C)=S,Valid +1095,8,Thionoester,COC(=S)C,COC(C)=S,Valid +1096,7,Thioamide,CC(=S)N,CC(N)=S,Valid +1097,6,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC,Valid +1098,10,Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +1099,4,Thiocyanate,SC#N,N#CS,Valid +1100,21,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1,Valid +1101,6,Dye 2,OCccCO,OCccCO,Valid +1102,2,Disulfide,SS,SS,Valid +1103,11,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N,Valid +1104,6,Oxalyl,O=C-&!@C=O,O=CC=O,Valid +1105,15,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-],Valid +1106,19,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1107,10,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O,Valid +1108,18,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12,Valid +1109,26,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21,Valid +1110,28,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O,Valid +1111,8,Propiolactone,C1(=O)OCC1,O=C1CCO1,Valid +1112,8,b-Lactam,N1CCC1=O,O=C1CCN1,Valid +1113,14,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +1114,25,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1115,17,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +1116,14,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +1117,57,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1,Valid +1118,15,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +1119,28,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1,Valid +1120,17,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1121,18,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1122,7,Acid_anhydrides,C(=O)OC(=O),O=COC=O,Valid +1123,20,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1,Valid +1124,6,Acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +1125,19,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F,Valid +1126,12,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C,Valid +1127,28,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O,Valid +1128,4,Aminonitrile,NC#N,NC#N,Valid +1129,13,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-],Valid +1130,7,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1131,21,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1,Valid +1132,14,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +1133,14,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1,Valid +1134,17,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1,Valid +1135,20,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1,Valid +1136,7,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +1137,19,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1138,6,Diacetylene,C#CC#C,C#CC#C,Valid +1139,11,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-],Valid +1140,7,Diazonium_salt,[N+]#N,N#[NH+],Valid +1141,15,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O,Valid +1142,7,Dithiocarbamate,NC(=S)S,NC(S)=S,Valid +1143,10,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1,Valid +1144,10,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1,Valid +1145,3,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS,Valid +1146,6,Enyne,C=!@CC#C,C#CC=C,Valid +1147,7,Ester_of_HOBT,C(=O)Onnn,nnnOC=O,Valid +1148,30,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2,Valid +1149,8,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF,Valid +1150,10,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F,Valid +1151,8,Four_member_lactones,C1(=O)OCC1,O=C1CCO1,Valid +1152,3,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN,Valid +1153,7,Geminal_dinitriles,N#CCC#N,N#CCC#N,Valid +1154,14,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1,Valid +1155,7,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S,Valid +1156,4,Nitrosamine,N-[N;X2](=O),NN=O,Valid +1157,8,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-],Valid +1158,3,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN,Valid +1159,9,Orthoester,C(O)(O)[OH],OC(O)[OH],Valid +1160,20,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH],Valid +1161,13,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1,Valid +1162,3,PCP,PCP,PCP,Valid +1163,25,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +1164,26,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1165,13,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1,Valid +1166,12,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O,Valid +1167,10,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +1168,12,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +1169,11,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc,Valid +1170,8,Polyines,CC#CC#CC,CC#CC#CC,Valid +1171,20,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1,Valid +1172,22,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12,Valid +1173,26,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1174,11,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1,Valid +1175,3,S=N (not_ring),[S;R0]=[N;R0],N=S,Valid +1176,9,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O,Valid +1177,10,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1178,3,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S,Valid +1179,9,Tetraazinane,C1NNC=NN1,C1NNC=NN1,Valid +1180,14,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S,Valid +1181,15,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1,Valid +1182,29,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1,Valid +1183,32,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1,Valid +1184,17,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O,Valid +1185,11,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O,Valid +1186,14,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1,Valid +1187,3,Thiocarbonyl_group,C=S,C=S,Valid +1188,3,Enamine_like,C=[NH],C=N,Valid +1189,14,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F,Valid +1190,4,Triple_bond,[#6]C#[CH],CC#C,Valid +1191,15,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O,Valid +1192,12,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1,Valid +1193,17,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1,Valid +1194,8,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1,Valid +1195,9,Thiazolidinone,O=C1CSCN1,O=C1CSCN1,Valid +1196,14,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1,Valid +1197,12,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1,Valid +1198,15,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1,Valid +1199,3,Ethene,C=[CH2],C=C,Valid +1200,7,Cyclobutene,C1CC=C1,C1CC=C1,Valid +1201,1,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C,Valid +1202,17,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-],Valid +1203,21,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-],Valid +1204,4,Sulphur atom (1),[SX2H1],[SH],Valid +1205,1,Sulphur atom (6),[sX2r5],s,Valid +1206,1,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C,Valid +1207,1,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C,Valid +1208,1,Nitrogen atoms (7),[nr5H0],n,Valid +1209,27,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21,Valid +1210,16,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C,Valid +1211,25,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1,Valid +1212,24,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1,Valid +1213,31,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1,Valid +1214,25,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1,Valid +1215,24,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1,Valid +1216,27,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1,Valid +1217,27,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1,Valid +1218,20,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1,Valid +1219,19,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1,Valid +1220,19,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1,Valid +1221,23,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1,Valid +1222,22,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2,Valid +1223,22,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC,Valid +1224,21,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1,Valid +1225,16,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1,Valid +1226,27,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1227,32,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1228,34,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1,Valid +1229,20,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1,Valid +1230,20,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1,Valid +1231,16,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1,Valid +1232,22,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1,Valid +1233,22,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12,Valid +1234,21,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1,Valid +1235,14,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1,Valid +1236,17,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1,Valid +1237,17,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1,Valid +1238,32,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1,Valid +1239,20,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1,Valid +1240,12,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2,Valid +1241,11,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2,Valid +1242,19,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1,Valid +1243,15,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2,Valid +1244,6,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid diff --git a/Experiments/BACE/running utils/medium.txt b/Experiments/BACE/running utils/medium.txt new file mode 100644 index 0000000000000000000000000000000000000000..21b65a9a233c409ecd425a64054237c77538aa21 --- /dev/null +++ b/Experiments/BACE/running utils/medium.txt @@ -0,0 +1,180652 @@ +O=C1Nc2cc(NC(=O)c3c[nH]cc(-c4ccc(C(F)(F)F)cc4)c3=O)ccc2C1=Cc1ccc[nH]1 +CC(NC(=O)Nc1cc2[nH]nc(N3CC(C(C)(C)O)C3)c2cn1)c1ccccc1 +N=C(N)C1CCCC(NC(=O)CN2CCCCC(NS(=O)(=O)c3ccccc3)C2=O)C1O +CCN1C(C(=O)NC(Cc2ccccc2)C(=O)C(=O)NCCCN2CCCC2=O)Cc2cc3c(cc2S1(=O)=O)OCCO3 +COCC(=O)NC1CCC(CCN2CCC(c3cccc4occc34)CC2)CC1 +O=C(c1cc(-c2ccc3[nH]ncc3c2)on1)N1CCCCC1 +CN(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1cccc(F)c1 +CC1(C)Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 +CCC(C)C(=O)C1CCC2C3CCC4NC(=O)C=CC4(C)C3CCC12C +C=CCc1cnc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)s1 +CC(C)CC(NC(=O)c1ccc(N2CCN(C)CC2)cc1)C(=O)N1CCC2OCC(=O)C21 +CCOc1ccc(-c2cccc(S(=O)(=O)NC(Cc3cccc(C(=N)N)c3)C(=O)N3CCC(CCN)CC3)c2)cc1 +COC(=O)C1OC(SNCc2ccc(S(N)(=O)=O)cc2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCCCCC2)CC1 +CCC(=O)NCC1CCCc2c1c1cc(OC(F)(F)F)ccc1n2C +Cc1ccnc(-c2nc3cc(F)cc(F)c3c(N3CC4(CCOCC4)c4ncc(N5CCOCC5)cc43)c2C)c1 +CC1CN(Cc2cccc(-c3cc(CNC(=O)c4cccc(CN5CCNCC5)c4)ccc3F)c2)CCN1 +O=C(O)C1CCCCC1NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CCCCC(CC)C(=O)OCC1(CO)CC(=Cc2ccccc2C(F)(F)F)C(=O)O1 +COc1cc(C(=O)NC2(C(=O)NC(C)c3ccc(-c4cc(Cl)cc(F)c4-c4nnn(C)n4)cc3F)COC2)on1 +O=S(=O)(c1cccc2ccccc12)n1ccc2c(N3CCNCC3)c(Cl)ccc21 +Cn1c(=O)c2c(nc(OCc3cccc(C(F)(F)F)c3)n2C)n(C)c1=O +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCCCC2)cc1 +COc1ccccc1NC(=O)N1CCN(Cc2ccc(Br)c(Br)c2)CC1 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccccc3CN(C)C)cc21 +COc1ccc(C(=O)NCC(c2ccccc2)N2CCN(CC(O)COc3ccc(Cl)cc3)CC2)cc1 +CCCCC(CC(CCc1ccc(-c2ccc(C=O)cc2)cc1)C(=O)NC(C(=O)NC)C(C)(C)C)C(=O)O +CN1C2CCC1C(c1cnc(Cl)c(-c3ccccc3)c1)C2 +Cc1cc(O)cc(C)c1CC(N)C(=O)NCCc1nc(O)c(CCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C +CC1(c2cc(NC(=O)c3cnc(-c4ncco4)cn3)ccc2F)C=CSC(N)=N1 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+O=C(NCC1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1)C1CCCC1 +COc1nn(-c2ccccc2)c2cc(N3CC(N4CCNCC4)C3)ccc12 +COc1ccccc1OCCNCCC(=O)N1CCCOc2c1cnn(C)c2=O +O=[N+]([O-])c1cccc2c1nc(Nc1c(Cl)cccc1Cl)c1cncn12 +CNc1nc(C)c(-c2nc(Nc3cccc(S(N)(=O)=O)c3)ncc2F)s1 +O=C(NCc1ccc(OC(F)(F)F)cc1)C1c2c(O)cccc2C(=O)N1CCc1ccccn1 +CCCN(c1c(OC)nn2c(-c3c(OC)cc(COCC)cc3OC)csc12)C1CCOCC1 +CN1CCC(c2c[nH]c3ccc(NS(=O)(=O)c4ccc(F)cc4)nc23)CC1 +CCCCCNC(=O)Nc1c(O)cccc1OCCCn1cnc(-c2ccccc2)c1C +CSc1c(Cl)nc(-c2ccc(NC(=O)Nc3ccc(NS(C)(=O)=O)cc3)cc2)nc1N1CCOCC1 +NC(=NOCC(O)CO)c1c(O)nsc1Nc1ccc(Oc2cc(Cl)ccc2Cl)cc1 +CN(C)CCSCCNc1ccc2c3c(nn2CCN(C)C)-c2cnccc2C(=O)c13 +O=C(NC1CCCCC1)c1cc(-n2cccc2)n(-c2ccc(Cl)cc2)n1 +Cc1c(SCc2ccc(COCCF)cc2)oc2ccccc2c1=O +COc1ccc2c(c1)C(=O)N(CC1(c3ccc(Oc4ccc5cnccc5c4)cc3)NC(=O)NC1=O)C2 +CCOC(=O)c1c(NC(=O)CSc2nnnn2-c2ccccc2)sc2c1CC(C)(C)NC2(C)C +O=C(NCCCNc1nc2ccc([N+](=O)[O-])cc2c2[nH]c3ccccc3c12)Nc1ccccc1 +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(CCc2ccncc2)cc1 +COCCNCc1cccc(C=Cc2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)c1 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+CC(=O)OC1C(N=[N+]=[N-])C2=CC(=O)CCC2(C)C2CCC3(C)C(=O)CCC3C12 +C[N+](C)(C)CC(CC(=O)[O-])OC(=O)CCCCC(=O)Nc1ccn(C2OC(CO)C(O)C2(F)F)c(=O)n1 +O=S(=O)(c1ccc(-c2ccnc(Nc3ccc(Cl)cc3)n2)cc1)N1CCNCC1 +Clc1ccc(Sc2nnc(Cc3ccncc3)c3ccccc23)cc1 +Cn1cc(-c2nc(C3(c4ccc(-c5cnc(N)cn5)nc4)CCC3)no2)cn1 +CN(C)C(=O)c1cccc2cc(CCc3c(C(=O)O)[nH]c(=O)[nH]c3=O)ccc12 +COc1cc(C=C2CCC(=Cc3ccc(OCCCCN4CCCCC4)c(OC)c3)C2=O)ccc1OCCCCN1CCCCC1 +COc1cccc(N2CCC(NC(=O)N(C)C3CCN(S(C)(=O)=O)CC3)CC2)c1 +Fc1cccc(CSc2cc3ccccc3[n+](CCCCCC3CCCCC3)c2)c1 +COc1ccc(NCCNC(=O)C(Cc2cccc(Cl)c2)NC(=O)c2cccc(C)c2)cc1 +O=C(NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1)C1CCOCC1 +COC1CN(c2nc(C(=O)N(C)C)c(C(=O)O)s2)CCC1NC(=O)c1[nH]c(C)c(Cl)c1Cl +FC(F)(F)c1cccc(-c2cn(CC3CC3)c(-c3cccc(CN4CCOCC4)c3)n2)c1 +O=C(O)C1CCCN(CCOCCN2c3ccccc3C=Cc3ccccc32)C1 +CCCN1CC=C(c2c[nH]c3ccc(C(=O)OC)cc23)CC1 +CC1(C)CN=C(c2ccc(-c3cccc(-c4ccc(C5=NCC(C)(C)CN5)cc4)c3)cc2)NC1 +COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(C(F)(F)F)cc1 +CCOC(=O)NC(=NCC1CCCCC1)NCCCc1c[nH]cn1 +COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccn(CC(=O)O)n3)cc21 +CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCOCC1)C2 +O=c1ccc2c(-c3ccccc3S(=O)(=O)O)c3ccc(O)c(O)c3oc-2c1O +Cc1cccnc1C(CC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1)Cc1cc(C)c2[nH]ncc2c1 +N=C(N)c1ccc(Oc2ccc(C(=O)N3CCC(CCN)CC3)c(Oc3ccc(C(=N)N)cc3)n2)cc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1ccnn1-c1ccccc1 +COc1cc2c(cc1N1CC(C)N(C)C(C)C1)N(C(=O)Cc1cccc(F)c1C(F)(F)F)CC2 +O=C(NC(CO)CC1CCC1)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(C)n1)CC2 +COc1ccc2c(OCc3nnc4ccc(-c5ccc[nH]5)cn34)ccnc2c1 +NCCC(NC(=O)OCc1ccccc1)C(=O)Nc1ccc2nc(N3CCNCC3)[nH]c(=O)c2c1 +Cc1nc2ccc(CNc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3F)cc2c(=O)[nH]1 +c1cc(NC2CCCNC2)nc(-c2cnc3ccccn23)c1 +CC(C)(C)OC(=O)NCc1ccc(C(=O)NC2CCOC2=O)cc1 +CC1(c2ccc(C(=N)N)cc2)NC(=O)N(CC(=O)NC(CC(=O)O)c2ccc3c(c2)OCO3)C1=O +NCC(=O)N1CCN(c2ccncc2NC(=O)c2nccnc2N)CC1 +COc1cccc(OC)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCC(C)CC1 +Cc1ccc(Nc2nc(N)c(C(=O)c3ccccc3)s2)cc1 +COc1cc(N2CCNCC2)c2c(c1)N(S(=O)(=O)c1ccccc1F)CCO2 +N#Cc1cnc2c(Nc3cc(F)c(F)c(C4(CF)CC(C(F)(F)F)OC(N)=N4)c3)nccc2c1 +O=C(NCCCCCCCCn1cc(-c2cccnc2)nn1)Nc1ccccc1-c1ccccc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(CC=Cc2ccccc2)CC1 +O=C(CCCCCCc1ccccc1)c1nnn(-c2cccs2)n1 +CN(C)C(=O)CCCCc1ccc(C(=O)Nc2sc(-c3ccncc3)nc2C(N)=O)cc1 +CCCC1NCCOc2ccccc2CCCNC(=O)C(Cc2ccccc2)NC(=O)C2(CCCC2)NC1=O +CN(C(=O)Nc1ccn(-c2ccccc2F)n1)C1CCC2(CC1)OCc1ccccc12 +Cc1cc(OCC2(C(=O)O)CCC2)ncc1-c1ccc(-c2nc(C(F)(F)F)c[nH]2)c(Cl)c1 +O=C(c1ccc(Cl)cc1Cl)N1CCn2c(nnc2-c2ccc(F)cc2F)C1 +COC(c1ccc(F)cc1)(c1ccc(F)cc1)c1cnn(C(=O)N2CCCCC2Cc2ccccc2)n1 +CC(Oc1cccc(Cl)c1)C(=O)N(CC1CCCN1)c1ccccc1Cl +COc1cc(C=NNc2nc(Nc3ccc(C)cc3)nc(-n3nc(C)cc3C)n2)cc(OC)c1OC +N#CCC(=O)N1CCCC(n2nnc3cnc4[nH]ccc4c32)C1 +O=C1NCN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2 +Cc1cc(CCN2CCCC2)c(C)c2c1N(CCN1CCCCC1)C(=O)C2=NNC(=O)C(C)c1ccc(O)cc1 +COCCCN1C(C=Cc2ccc(-n3cnc(C)c3)c(OC)c2)=NOC1(C)c1ccc(F)cc1 +O=C(c1ccc2c(c1)[nH]c(=O)c1cnn(C3CCCC3)c12)N1CCc2cc(Cl)ccc21 +COc1cc2c(N)nc(N3CCN(C(=O)CC(c4ccc(F)cc4)N4CCCC4)CC3)nc2c(F)c1OC +Cc1cccc(NCc2nc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)[nH]2)c1 +CSc1ccc(CN2CCC(Oc3ccc(C(=O)N4CCCC4)cc3)CC2)cc1 +NCCc1c[nH]c2ccc(Cc3nc(-c4ccccc4)no3)cc12 +O=C(Nc1cccc2[nH]ncc12)NC1CCc2cc(Cl)ccc21 +CCC(Oc1nc(-c2ccc(OC(C)C)c(OC)c2)cc2ncccc12)C1CNC(=O)C1 +O=C(Nc1ccc(F)cc1F)Nc1cccnc1Oc1cccc(C(F)(F)F)c1 +CC(C)Oc1cc(CCC(=O)NS(=O)(=O)C2CCCCC2)n(Cc2ccc(Cl)cc2Cl)n1 +ON=Cc1c(O)ccc(-c2ccc(O)cc2)c1-c1ccc(O)cc1 +CN1CCN(CCCCOc2ccc(N3C(=O)C(=Cc4ccc(Oc5ccc(C(N)=O)cc5)cc4)SC3=S)cc2)CC1 +CCc1c(-c2cncc(C)c2)nn2c1N(C)C(=O)CC2 +CC(C)(O)Cn1cc(-c2cc(CO)c3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +O=C(Nc1ccccc1)N1CCN(Cc2cccc(Oc3cccc(Cl)c3)c2)CC1 +CCCSc1nc2c(c(Nc3ccc(C(F)(F)F)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +Nc1ncnc2c1ncn2C1OC(OCP(=O)(NC(Cc2ccccc2)C(=O)OC2CCC2)Oc2ccccc2)C=C1F +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OC[Si](C)(C)c2ccc(F)cc2)c1 +CC(C)(CO)Nc1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +CS(=O)(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F 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+N#Cc1ccc2c(c1)cc(C(=O)NCCC(O)C(F)(F)F)n2Cc1cccc(OC(F)(F)F)c1 +CN(C)CC(=O)N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +COC(=O)NCCSSCCNC(=O)C(Cc1ccc(O)c(Br)c1)=NO +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)C3=CC4C=NNC4C=C3)CC1)C2 +CCN1CC(C)(C)Oc2nc(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)Nc4ccc(F)cc4F)cc3)c2C1=O +Cc1cc(C(=O)N2CCCC2)cc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1 +CN1CCN(Cc2ccc(NC(=O)c3cccc(NC(=O)c4cnc5[nH]ccc5c4)c3)cc2C(F)(F)F)CC1 +[C-]#[N+]c1ccc(C(=O)Nc2ccc(F)c(C3(C)CC(C(F)(F)F)OC(N)=N3)c2)nc1 +COc1ccc(NC(=O)c2c(C)[nH]n(-c3ccccn3)c2=O)cc1F +C[N+](C)(C)CCCCCCCCCCCC[N+](C)(C)C +CCN(CC)CCc1c(-c2ccccc2)sc2ccc(Cl)cc12 +CCC1CCC2C3CCC4CC(OS(=O)(=O)O)CCC4(C)C3CCC12C +CC1C=CC(=O)C(O)C(O)CC=Cc2cc(NC3CC3)cc(O)c2C(=O)OC1C +C#CCn1c(=O)c(I)cn(Cc2cn(-c3ccc(Cl)cc3)nn2)c1=O +COc1ccc2c(c1)OC(C)(C)C(c1ccccc1)C2c1ccc(OCCN2CCCC2)cc1 +N#CNC(=Nc1cccc(Oc2ccccc2)c1)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +Nc1nccn2c(C3CC(O)C3)nc(-c3ccc(C(=O)c4ccccc4)cc3)c12 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2cccc(Cl)c2)CCN(C(=O)C(C)(C)C)CC1 +O=C(C1CNCCC12OCc1cc(F)c(F)cc12)N(Cc1nccc2ccccc12)C1CC1 +O=C1C(CCO)OC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N1CC1CC1 +Cn1nc(C(=O)Nc2ccccc2)c2c1-c1nc(Nc3ccccc3)ncc1CC2 +O=C1OC(COc2cccc3ccccc23)(c2ccccc2)CC(O)=C1SCc1ccccc1 +CN(C)C1CCN(c2cc(Nc3cc(Cl)ccn3)nc(-c3ccccc3)n2)C1 +CCc1c(C(=O)NC)cn2ncnc(Nc3ccc4c(cnn4Cc4ccccc4)c3)c12 +OCCN(CCO)c1nc2ccccc2n2nc(-c3ccco3)nc12 +COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O +Nc1nonc1-n1nnc(-c2n[nH]c(-c3ccncc3)n2)c1CN1CCCC1 +O=C(NC1CCCCCC1)C1CCN(S(=O)(=O)c2ccccc2)CC1 +CC1(C)CC(=O)c2cnc(Nc3ccc(Cl)cc3)nc2C1 +N#Cc1cc(Cl)cc(Oc2c(Br)ccc(Cc3n[nH]c4ncccc34)c2F)c1 +CCN(CCCCOc1ccc(-c2coc3cc(OCCCCN(CC)Cc4ccccc4)cc(O)c3c2=O)cc1)Cc1ccccc1 +Cc1nc(NC(C)c2cncc(-c3cnn(C)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 +O=C(Nc1ccccc1[N+](=O)[O-])C1CCCN1C(=O)NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1 +Cc1sc2nc(CCCCN3CCN(c4ccc5ccccc5n4)CC3)n(N)c(=O)c2c1C +N=C(N)c1ccc2cc(-c3cccc(OCCCCOc4ccccc4)c3)oc2c1 +N=C(N)c1cc2c(OC(COC(=O)Nc3cccc(F)c3)c3ccccc3)cccc2s1 +Cc1cc(C)[n+](CC(=O)OCCc2ccc(S(N)(=O)=O)cc2)c(C)c1 +CCc1c(Cc2ccccc2)nc(SCC(=O)c2ccc(OC)cc2)[nH]c1=O +COc1ccc(S(=O)(=O)NCCc2cccc3cc(F)ccc23)cc1N1CCNCC1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CC(F)(F)C(F)(F)C3)ns2)n1 +O=C1C(N2CCCCC(c3ccc(O)cc3)C2)CCN1Cc1ccc(F)cc1 +CCCCCCCNC(=O)Oc1ccc2c(c1)CN(C)C(c1cccc(C)c1)N2C +CNc1n[nH]c2ccc(C(=O)N3CCCC3c3ccc(Cl)cc3)cc12 +CN(C(=N)Nc1cccc2ccccc12)c1cccc(Br)c1 +Cc1noc(C)c1Cn1cc(NC(=O)c2cccc(Cl)c2)cn1 +CCc1cc(C=CC(=O)O)ccc1NC(=O)c1cccc(NC2=NCCN2)c1 +CCCc1cc(C2=NC3OCCCC3S2)ccc1OCCCOc1ccc2c(c1)CCC2CC(=O)O +CC(C)(C)c1cc(-c2ccccc2)cc(-c2ccccc2)[n+]1Cc1ccc(S(N)(=O)=O)cc1 +CCN1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 +Cc1cc(NC(=O)C(C#N)=C(O)C2CC2)ccc1C#N +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCC5CC5)s4)nc23)N1 +CC(NC(=O)CCc1nc2ccncc2n1Cc1ccc(OC(F)(F)F)cc1)c1ccc(Cl)cc1 +C(=CCN(CC1Cc2ccccc2CN1)C1CCCc2cccnc21)CNCc1ccncc1 +CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1C1CCC(F)(F)C1 +COc1cc(OCCN2CCc3ccccc3C2)ccc1C=NNC(=O)c1ccc(O)c(Cl)c1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1 +CCCn1c(=O)c2nc(C3CCc4ccccc4C3)[nH]c2n(CCC)c1=O +CC(C)C1c2[nH]cnc2CCN1C(=O)OCCOc1ccccc1 +CN1C(=O)c2ccccc2[S+]([O-])c2ccc(C(=O)NCc3cccnc3)cc21 +O=C(NCc1ccc(Br)cc1OC(F)(F)F)c1ccc(OCCC(F)(F)F)nc1 +CS(=O)(=O)Nc1cccc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC3(C#N)CC3)n2)c1Cl +COc1cccc(C(=N)NCCCCCCCCCCCCNC(=N)c2cccc(OC)c2)c1 +COc1c(OCC(C)(C)OC)ncnc1N1CCC(Oc2ccc(C(C)NC(C)=O)cc2)C1 +O=C(C=Cc1ccc(C(F)(F)F)nc1N1CCCCC1)Nc1ccc2c(c1)OCCO2 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(N2CCOCC2)cc1 +O=S(=O)(NCc1ccco1)c1ccc(NC2CC3CCC2C3)cc1C(F)(F)F +O=S1(=O)c2cccc3cccc(c23)N1CCCN1CC=C(c2c[nH]c3ccc(O)cc23)CC1 +COc1ccc2c(c1)c(CN1CCNCC1)cn2S(=O)(=O)c1ccccc1Br +COCC1CN(c2n[nH]c3cc(NC(=O)NC(C)c4ccccc4)ncc23)C1 +Cc1nsc(-c2nnc3n2CCN(C(=O)c2ccc(F)c(F)c2)C3C)n1 +CC(=O)N(C)Cc1cc(-c2ncco2)ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C +COCC(COC)N1CCc2cn(-c3ccc(Cl)cc3C#N)c3nc(C)cc1c23 +COc1cc(O)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(=O)NC1CCS(=O)(=O)C1 +CCCOCCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +O=C(NCc1cc(Br)cc2nc(O)c(O)nc12)c1ccncc1 +Cc1nc(-c2c(F)cc(Cl)cc2-c2cnc(C(C)NC(=O)C3(NC(=O)c4nnc(C)o4)COC3)c(F)c2)no1 +Cn1c(=O)c2c(nc(C=Cc3ccc(Cl)cc3)n2C)n(C)c1=O +Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)on1 +COc1cccc(N(C(C)c2ccccc2OCCCN2CCCC2)S(=O)(=O)c2ccc(Cl)cc2)c1 +CCCCCCCCCCCCc1cc(C(C(=O)Nc2c(C(C)C)cccc2C(C)C)c2ccccc2)on1 +CC(=Nc1ccc2c(c1)C(NC(=O)c1ccc(Br)cc1)C(O)C2)NCCc1ccc(F)cc1 +Cc1cnc(N2CCN(CCC3CCC(NC(=O)C4CCOCC4)CC3)CC2)c2ccoc12 +COC(=O)NCc1cc(-c2sc(-c3cccnc3)nc2N2CCCCC2)n[nH]1 +Cc1cc(C2CCN(C)CC2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 +O=C(Nc1ccc(-c2nc(N3CCOCC3)c3cccnc3n2)cc1)Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1 +CN1CC=C(c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)CC1 +COc1cccc(S(=O)(=O)Nc2cc3c(cc2Oc2ccccc2)n(C)c(=O)n3C)c1 +CCOc1cc(NC2(CCCN)CC2)c2nc(C(F)(F)F)ccc2n1 +CC(C)(C)C(=O)CS(=O)(=O)c1cnnn1-c1ccccc1 +Cc1nnc2n1-c1c(F)cc(-c3cncc(F)c3)cc1CC2 +CNc1cccc(Nc2nc(N)c(C(=O)c3cccc(F)c3)s2)c1 +N#Cc1c[nH]c2nc(Nc3ccccn3)cc(-c3ccccc3)c12 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3ccc(C4CC4)cc3)cc2)C1CO +NCCCC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1 +Cc1cc(N2CCCC2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +Nc1nc(SCCO)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 +O=C(O)c1ccc(NC(=O)c2nc3ccccc3nc2Oc2ccc(F)cc2F)cn1 +COc1ccnc2c1C(=O)c1c(-c3ccccc3NC(=O)C(F)(F)F)ccnc1C2=O +CN1CCN(C2CC(c3ccc(F)cc3)c3ccc(C(F)(F)F)cc32)CC1(C)C +CCC(O)=C(C#N)C(=O)Nc1ccc(-c2cccnc2)c(C(=O)OC)c1 +CC(C)CN1CCN(c2nc3c(c(Nc4ccc(C(F)(F)F)cc4)n2)CCN(c2ncccc2C(F)(F)F)CC3)CC1 +Cc1ccccc1-c1ccccc1C=NNc1c(Cl)cncc1Cl +CCCCCCSCC1C2CCC(O2)C1CC=CCCCC(=O)O +COc1cc(C(=O)NC(Cc2ccccc2)C(O)CO)ccc1-c1cn[nH]c1 +CC(C=NOCCCN)=CC1CCC2(O)C3CCC4CC(O)CCC4(C)C3CCC12C +CC(C)N1CCc2nc(O)n3nc(-c4ccccc4F)nc3c2C1 +CC(C)Cn1c(=O)n(C)c(=O)c2c(S(=O)(=O)N3CCC(O)C3)c(Cc3ccccc3C(F)(F)F)sc21 +Cc1cc(SSc2cc(C)nn2-c2ccccc2)n(-c2ccccc2)n1 +COc1ccc(C2(Cc3ccncc3)CCNC2=O)cc1OC1CCCC1 +O=C(CN1CCCCC1)N1CCc2nc(O)c3ccccc3c2C1 +CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCC(C)C4)n3)cc2)C1=O +COC1CCN(C(=O)c2ccc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)cc2F)CC1 +O=C(O)CC(NC(=O)CNC(=O)c1cncc(NC2=NCC(O)CN2)c1)c1cc(Cl)cc(I)c1O +COc1ccc(NC(=O)Nc2ccc(C(F)(F)F)cc2)cc1-c1c(Br)cnn1C +CCCCNC(=O)c1cnc(N2CCN(C3CCN(Cc4ccc(Cl)cc4)CC3)CC2)c(Cl)c1 +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1nccs1 +O=c1[nH]n(Cc2ccncc2)c(=O)c2c(=O)c3ccc(Cl)cc3[nH]c12 +Cc1nc(N)ccc1CNC(=O)C1C=CCn2c(=O)n(C(CSc3ccc(Cl)cc3)C(=O)O)c(=O)n21 +Cc1ccc(OCC(=O)NC2c3cc(NC(=O)COc4ccc(C#N)cc4C)ccc3CC2O)cc1 +O=C(C(c1ccc(Cl)cc1)c1cccnc1)N1CCN(c2nccs2)CC1 +CCOc1ccc(CC(NC(=O)c2ccccn2)C(=O)NC(Cc2cccs2)C(=O)NCc2ccc(CN)cc2)cc1 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1ccc2c(c1)ncn2Cc1ccccn1 +CCS(=O)(=O)c1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2CN2C(=O)COC2=O)cc1 +N#CC1(NC(=O)C(Cc2ccc(Cl)c(Cl)c2)NC(=O)c2cnn(C3COC3)n2)CC1 +NC(CNc1cc(-c2ccncc2)c(-c2cccc3ccccc23)nn1)Cc1ccc(F)cc1 +Oc1nc2cc(C#CCN3CCC(CCc4ccc(F)cc4)CC3)ccc2[nH]1 +CCC(NC(=O)c1ccc(C(=N)N)cc1)C(C)(C)C(=O)N1CCC(CC(=O)O)CC1 +Cc1cn2cc(C(F)(F)F)cc2c(C#Cc2ccc(F)cc2)n1 +CCOc1ccccc1C(=O)c1cnc(NC2CCN(C(C)=O)CC2)nc1N +Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccnnc3)c1)=N2 +COc1cc2c(cc1OC)CN(Cc1ccc(-c3ccc(O)cc3)cc1)CC2 +Cc1[nH]cnc1CSCC(=O)NC(=N)NCCCc1c[nH]cn1 +COC(=O)c1c(Cl)cc(Cl)cc1-c1ccc(C(C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1 +COc1cnc(N2CCOCC2)c2sc(NC(=O)C(C)(C)Oc3ccc4c(c3)OCO4)nc12 +N#CC1CCCN1C(=O)C(N)CCC(=O)N1CCc2ccccc2C1 +Cc1ccc(C=CC(=O)NC(Cc2ccccc2)C(=O)NC(C=O)CC2CCNC2=O)cc1 +COc1c(C)cnc(CN2c3nc(N)nc(Cl)c3NC(=O)C2C(C)C)c1C +O=C(CSc1nc2ccccc2s1)N1c2ccccc2Sc2ccc(C(F)(F)F)cc21 +N#CSc1ccc(CCCN2CCN(CCCN(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1I +Fc1ccccc1N1CCN(Cc2cnn(-c3ccccc3)c2)CC1 +COc1cc(C2c3cc4c(cc3C(CCN(C)N(C)C)C3COC(=O)C23)OCO4)cc(OC)c1O +CC(C)n1cc(-c2cccc(-c3cnc(N)c(C(=O)NC4C5CC6CC4CC(O)(C6)C5)n3)c2)cn1 +COCCNC(=O)Nc1cc2[nH]nc(-c3cc(C)nc(OC)c3)c2cn1 +CCC1(CC)CC(=O)C(C2C3=C(CC(CC)(CC)CC3=O)Oc3ccccc32)=C(O)C1 +Cc1cc(-c2ccc3c(c2)CCN(CCCSc2nnc(-c4cccn4C)n2C)CC3)no1 +CCC(CC(O)C(N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NCC1(CO)CCCC1 +CC(=N)N1CCC(Oc2ccc(NCC(C)=Cc3cccc(C(=N)N)c3)cc2[N+](=O)[O-])CC1 +Cc1cc(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2)nc(C)n1 +O=C1C(=NNc2cccc3c(=O)[nH][nH]c(=O)c23)C(c2ccccc2)=NN1c1ccccc1 +NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)c2c(F)c(F)c(F)c(F)c2F)s1 +CC1CCC2C(C)C(OC(=O)c3ccc(C=CC(=O)c4ccccc4)cc3)OC3OC4(C)CCC1C32OO4 +Clc1ccc(-c2ccc(C#Cc3ccc(OCCN4CCCC4)cc3)nc2)cc1 +Clc1cc(Nc2nc(NCc3ccccc3)c3ccccc3n2)ccc1Br +COc1cc(-c2cn[nH]c2)ccc1NC(=O)C1COc2ccc(C)cc2C1 +COC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4ccsc4)c(F)cc3C)cc1OC2 +CCCc1cc2c(cc1N1CCN(C3CCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +O=C(Nc1cccc2nsnc12)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OC4CCCC4O)c3)C2)cc1 +COc1cc(-c2ccc(F)c(C)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccnc(C)n3)ccc21 +O=C(CSc1nnc(Nc2ccccc2)s1)NN=Cc1ccc(-c2cccc(Cl)c2)o1 +CCOc1ccc(S(=O)(=O)N2CCN(CCO)CC2)cc1-c1nc(O)c2nnc(C3CCCC3)n2n1 +COc1cc(Cn2nc(C(=O)O)cc2C)c2nc(N3CC=CCC3)sc2c1 +Oc1ccc(-c2c(-c3ccc(OCCN4CCCCC4)cc3)nn3c(C(F)(F)F)cc(C(F)(F)F)nc23)cc1 +CCC(=O)Oc1cccc(-c2nc(N3CCOCC3)c3cc4ncccc4n3n2)c1 +Cc1cc(Br)cc(C)c1Oc1cc(Nc2ccc(C#N)cc2)nnc1Cl +CN(CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21)Cc1coc2ccccc12 +Cc1cccc(CNc2nc(-c3ccccc3C(C)C)ncc2C)c1 +CCNC(=O)c1c(C2CC2)nc(CC)n1Cc1ccc2oc(-c3ccccc3NS(=O)(=O)C(F)(F)F)c(Br)c2c1 +CN(C)C1(C(=O)Nc2cccc(-c3ccncc3)c2)CCN(c2ncnc3[nH]c4c(c23)CCCC4)CC1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCN(C)CC2)n1 +CCOc1cc(CN2CC3(CC(c4ccc(CO)cc4)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +CCN(CC)S(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1 +COC(=O)c1oc(C(C)(C)C)cc1NC(=O)Nc1ccc(C)cc1 +Cn1cc(S(=O)(=O)c2ccc3c(c2)c2c(n3C)CC3CCC2N3)c2ccccc21 +Nc1ccnc(N2CCC(NC(=O)C3CCCO3)(c3ccccc3)CC2)c1 +NS(=O)(=O)Oc1ccc2cc(-c3cc(F)c(F)c(F)c3)c(=O)oc2c1 +[C-]#[N+]C1=C(C)Nc2oncc2C1c1ccc2[nH]nc(OC)c2c1 +COc1ccc(C2C(c3ccc(NC(=O)C(N)CCCCN)cc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1 +COCCNc1ncc(Oc2cc(I)c(OC)cc2C(C)C)c(N)n1 +Cn1c(=O)c2c(nc(COc3cccc(Br)c3)n2C)n(C)c1=O +CC(NC(C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)O)C(C)C)C(=O)O +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CCN(C(=O)NC(C)(C)C)C1)CC2 +CC1(O)CCCN(S(=O)(=O)c2ccc(OCc3ccc(F)cc3Cl)cc2)C1C(=O)NO +C=CCCCCCCCCCCCCCCOCCOP(=O)(O)COC(CO)Cn1cnc2c(N)ncnc21 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1CCCc2ccc(C(C)(C)C)cc21 +COc1cc(-c2cncc(NC(C)c3cccc(NC(=O)c4cccnc4)c3)n2)ccc1O +NC(=O)c1cc(-c2cnc(Nc3ccc(N4CCOCC4)cc3)c3nccn23)co1 +CCOC(O)=C1C(COCCN(C)C)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +O=C1c2cccnc2-c2nccc3c2c1nc1ccc(N(CCCl)CCCl)cc13 +O=c1ccc2c(N3CCN(CCCCOc4ccn5nccc5c4)CC3)ccc(O)c2[nH]1 +OCCCc1n[nH]c2c(Cl)ccc(Nc3c(-c4ncccn4)oc4cnccc34)c12 +COc1cc(N2C(=O)c3ccc(-c4ccccc4)cc3C2=O)ccc1OCCN(C(C)C)C(C)C +CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1CC2OCOC2C1)S(=O)(=O)c1ccc(CO)cc1 +O=C(Nc1cc(Cl)c(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1Cl)Nc1ccccc1Br +O=C(NC(c1ccc(Cl)c(F)c1)C1CCCN1)c1ccc2cnc(NC3CCOCC3)nc2c1 +NC(=O)c1sc2nc(NC3CC3)nc(-c3cccc(O)c3)c2c1N +O=C(OCc1ccoc1)c1cnn2c1n[n+]([O-])c1ccc(Cl)cc12 +CC(C)(C)c1cc(NC(=O)Nc2cc(Br)cc(Br)c2)no1 +CN(C)CCC(NC(=O)C=Cc1ccccc1)c1ccc(Cl)cc1 +CCC1CCCC(C2(CC(=O)N3CC4CCC(C3)N4C)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCCCC(CC)CNc1ncc(C(=O)OCC)c2nc(-c3ccco3)nn12 +CC(c1ccc(F)c(OC(F)(F)F)c1)N1C(=O)CS(=O)(=O)c2ccsc21 +Cc1cccc(OCC(=O)N2CCN(c3nc(N)nc4sccc34)CC2)c1 +C#Cc1cccc(Nc2nc3cc(-c4nnn[nH]4)ccc3c3sccc23)c1 +COC1CCCN(c2cc(-c3n[nH]c4ccc(OC(C)C)cc34)ncn2)C1 +COc1ccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cc1Cl +O=C(C=Cc1ccc(N2CCCCC2)cc1)c1ccc(OC(=O)N2CCCC2)cc1O +COC1C(=O)N(C(C)=O)C1C(C)=Cc1ccccc1 +CS(=O)(=O)Oc1cccc(CC2CN=C(N)N=C2N)c1 +Fc1ccc(Cn2c(N3CCC(n4cccn4)CC3)nc3ccccc32)cc1 +CCn1c(=O)n(C(=O)NCCN2CCN(C(C)C)CC2)c2ccccc21 +NS(=O)(=O)c1ccc(C2=C(c3ccc(C(F)(F)F)cc3)CC3(CC3)C2)cc1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(F)nc4)cc23)c1F +CC(C)OC(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +O=C(Cn1c(-c2ccc(Cl)cc2)nc2cccnc21)Nc1ccccn1 +CCn1nc2c(c1C)OC1(CCN(C(=O)c3cc(C)c4[nH]nc(C)c4c3)CC1)CC2=O +CCCS(=O)(=O)Nc1ccc(Cl)c(-c2cc3cnc4[nH]ncc4c3cc2OC)c1Cl +O=C(Nc1cc2[nH]nc(OCC(F)F)c2cn1)NC(c1ccccc1)C1(O)CCCC1 +CCC(C)C(N)C(=O)N1C[S+]([O-])CC1C#N +COC(=O)C1C(C=Nc2ccc(OC)cc2)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +Cc1c(C(=O)OC(C)C(C)(C)C)cn2c1C(=O)N(CCF)CC2 +O=C(COc1cccc2[nH]cc(Sc3ccc(F)cc3Cl)c12)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +CCC(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +Cc1cc(C(=O)NC(CC(=O)NCC(C)(C)C)C(=O)NC(CCc2ccccc2)C(=O)NCc2ccccc2)no1 +N#Cc1c(NNC(N)=S)nc(SCc2nc3ccccc3[nH]2)nc1-c1ccccc1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-n3cccn3)cc2)c1C +Cc1nc(-c2c(F)cc(Cl)cc2-c2cnc(C(C)NC(=O)C3(NC(=O)c4ccno4)COC3)c(F)c2)no1 +CCOc1cc2c(-c3cccc(S(N)(=O)=O)c3)n[nH]c2cc1-c1cn[nH]c1 +CN(N=Cc1cc(Br)cc(Br)c1O)c1cccc(C(F)(F)F)n1 +CCCCC1=NC(C)(C)C(C(=O)OCC)=C(Cl)N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(c1ccc(OCc2ccccc2)cc1)N(CCc1ccccc1Cl)C1CCNC1 +CCN(C)C(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(N(CCN(C)C)S(C)(=O)=O)cc1)c1ccccc1 +OC1CCC(Nc2cc(-c3cccc(NCC4CCCNC4)n3)c(Cl)cn2)CC1 +CC1(C)C2CCC(C[N+](C)(C)Cc3ccc(-c4ccccc4I)cc3)C1C2 +CC(C)(C)NC(=O)c1ccccc1CC(O)C(Cc1ccccc1)NC(=O)C(CSCc1ccccc1)NS(C)(=O)=O +Nc1nccn2c(C3CCCCC3)nc(-c3ccc(Oc4ccccc4)cc3)c12 +Cc1cc(Oc2ncccc2F)ccc1-c1c(C)c(=O)[nH]c(=O)n1C +CSc1nn2cc(-c3cc4c(OCc5cccc(OCc6ccccc6)c5)cc(OS(=O)(=O)C(F)(F)F)cc4o3)nc2s1 +CON(C)C(=O)C=Cc1ccc(C(=O)NCc2ccccc2C(F)(F)F)cc1 +CCN(CC)CC1CCCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)C1 +CCCC12CCC(=O)C(Br)=C1c1ccc3[nH]ncc3c1C2 +CNC(C)C(=O)Nc1ccc2c(n1)CN(C1CCN(C(C)=O)CC1)C(=O)N2c1cccc(Cl)c1 +COCCN(C)C(C)(C)c1ccc(NC(=O)c2ncc(C#N)[nH]2)c(C2=CCC(C)(C)CC2)c1 +CCCNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc3C)CC2)ncn1 +C=C(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +COc1cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)ccc1F +C=C(C)n1c(=O)n(Cc2nc3cc(C(=N)N)ccc3n2CCC(C)C)c2ccccc21 +O=C1NC(C(=O)O)CCCCCCc2cccc(c2)CC1CS +CCCCC(Sc1nc(OCCc2ccccc2)cc(OCCc2ccccc2)n1)C(=O)O +N#Cc1ccc(-c2ccc(C(=O)N(Cc3ccccc3-c3cccnc3)c3ccc(N4CCNCC4)cc3)o2)cn1 +CC(C)=CCCC(C)=CCOC(=O)C=Cc1ccc(O)c(O)c1 +O=C(OC1CCCCC1OC(=O)c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 +COCC[n+]1ccc(CCC(=O)C2Cc3cc(OC)c(OC)cc3S2)cc1 +COc1cc(C=NNc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)ccc1OC(=O)c1ccco1 +Nc1nccc(-c2c(-c3ccc(F)cc3)nn3ccccc23)n1 +CCCn1cc(-c2cn3ncc(C(N)=O)c(NC4CN(C(=O)C5(C#N)CC5)CC4C)c3n2)cn1 +Cn1cc2c(nc(N3CCCCC3)n3nc(-c4ccco4)nc23)n1 +CCCn1c(=O)c2nc(-c3cnn(Cc4cc(-c5ccc(OC)cc5)on4)c3)[nH]c2n(CCC)c1=O +CN1C(=CC=Cc2oc3ccc(Cl)cc3[n+]2C)Sc2ccc(Cl)cc21 +CC(C)CC(CC=C1CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O)CC(C)C +Fc1ccc(-c2n[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOCC4)N3)n2)cc1 +CC(C)C1CCC(N2CCC3(CC2)C2CN(c4ccccc4)CC2CN3c2ccccc2)CC1 +COc1ccc(-c2nc(C(=O)NCCCCC(=O)NO)cc3c2[nH]c2ccccc23)cc1 +N#Cc1cc(-c2ccnc(N)n2)ccc1OCc1ccc(F)cc1C(F)(F)F +COc1ccc(CSc2nc(O)c(C)c(Cc3c(F)cccc3F)n2)cc1 +Nc1nc(-c2cccc(C(=O)NCCc3ccc(O)cc3)c2)cn2nc(-c3ccco3)nc12 +COc1ccc2cc3[n+](cc2c1OCCC(=O)Nc1ccccc1)CCc1cc2c(cc1-3)OCO2 +CC(=O)NC(C)c1ccc(OC2CN(c3ccc(C(C)(C)C)cc3)C2)cc1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C#N)ccc43)s2)c1 +O=C(Nc1n[nH]c2nc(-c3cccs3)c(Br)cc12)C1CC1 +CC(C)c1nn2ccccc2c1Cc1ccc(C(=O)NC2CCOCC2C(=O)NO)cc1 +CCOCC(NC(=O)CCN)c1cc(F)ccc1N1CCN(C(=O)CCc2ccc(Cl)cc2Cl)CC1 +COc1ccc(Nc2nnc(-c3cccnc3NCc3ccccn3)o2)cc1 +COc1ccc(S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2C(=O)NO)cc1 +CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCc2ccccc2)CC1C +N#Cc1ccc(Cn2cc(C(=O)C(=O)Nc3ccc4ncccc4c3)c3ccccc32)cc1 +COc1ccc2ncc(-c3ccc(C(F)(F)F)cc3)n2n1 +CCc1[nH]c(=O)c(Cc2ccc3oc4ccccc4c3c2)c2cc(OC)c(OC)cc12 +CCCc1nc(-n2cccc2C(=O)O)c(C(N)=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1coc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)F)c1 +Cc1cc(C(=O)N(C(=S)OCCN2C(=O)c3ccccc3C2=O)c2ccc(Cl)cc2)ccc1Br +Cc1ccc(C(=O)n2nc(-c3cccnc3)nc2N)cc1 +OCC1C2CN(Cc3ccccc3)C(c3ccccc3)C2C1N1CCCC1 +CCCn1c(=O)n(Cc2ccc(N=[N+]=[N-])c(I)c2)c(=O)c2[nH]c(-c3ccc(OCC(=O)O)cc3)nc21 +NC1=NC(=O)C2CCCN2c2ccc(cc2)OCC=CCCCNCC(=O)Nc2c(Cl)cc(cc2Cl)CN1 +O=C(NC1CCCCCC1)C1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1 +COc1cc2c(N)nc(N3CCN(C(=O)CC4CCCNC4)CC3c3ccccc3)nc2c(F)c1OC +COc1cc(C=C2COc3ccc(Br)cc3C2=O)cc(OC)c1 +CCCOCCn1c(=O)c(NCCOCC)nc2cnc(-c3ccc(OC)nc3)cc21 +CN(C)Cc1ccc(CN2CCN(c3ccc(C(=O)NO)cc3)C2=O)cc1 +O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1)c1ccc2nn[nH]c2c1 +CC1(C)C=C(Cn2cnc3c(C(N)=O)cccc32)C(C)(C)N1O +NC(=O)C12CC3CC(C1)C(NC(=O)C1(CNS(=O)(=O)c4ccc(F)cc4C(F)(F)F)CC1)C(C3)C2 +COc1ccc2cc1Oc1ccc(cc1)CC1c3c(cc(OC)c4c3Oc3cc5c(cc3O4)CCNC5C2)CCN1C +CCC1CN(C(=O)c2cc(C)ccc2-n2nccn2)C(Cc2cccc(-n3nccn3)c2)CO1 +CCCc1nc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)cn1-c1ccc(F)cc1 +NC(=O)c1ccc2[nH]c(-c3ccc(C(O)c4ccc(Cl)c(C(F)(F)F)c4)cc3)nc2c1 +Cc1cccc(-n2c(-c3ccc(S(N)(=O)=O)cc3)coc2=O)c1 +CN1CC(c2csc(N)n2)n2nc(C(=O)NCc3ccc(F)cc3)c(O)c2C1=O +Nc1nccnc1C(=O)Nc1cnccc1N1CCCC(N)C1 +N#Cc1nc(-c2ccnc(Nc3ccc(NC(=O)CN4CCC(F)C4)nc3)n2)ccc1N1CCC(O)C1 +NS(=O)(=O)C(F)(F)c1ccc([N+](=O)[O-])cc1 +Cc1cc(C)c(-n2c[n+](CC(=O)c3ccc4ccccc4c3)c(C)c2C)c(C)c1 +CNC(=O)CN1CCC(c2cc3c(-c4cc(F)ccc4OC)ccnc3[nH]2)CC1 +Cn1c(CNc2ccnc3cc(Cl)ccc23)nc(-c2ccccc2)c1CN1CCCC1 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+CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N(C)C4CCCC4)c3)C2)cc1 +CNS(=O)(=O)N(C)C1CCN2CCc3ccccc3C2C1 +O=c1c(C(c2cccs2)c2c(O)oc3ccccc3c2=O)c(O)oc2ccccc12 +Cc1ccc(-c2c(CN)c(CC(C)C)nc3ccc(N4CC(=O)NCC4=O)cc23)cc1 +Cc1nnc(C(=O)COc2ccc(OCc3ccccc3)cc2)o1 +Cc1ccc(C(O)c2cccc(C(C#N)=C(N)Sc3ccccc3N)c2)cc1 +COc1cccc(SCCOc2ccc(CC(Nc3ccccc3C(=O)c3ccccc3)C(=O)O)cc2)n1 +O=C(Nc1ccc(C(=O)N2CCCc3c[nH]c4cccc2c34)cc1)c1ccccc1-c1ccccc1 +CC(C)n1c(C#CP(=O)(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c2ccccc21 +NS(=O)(=O)c1ccc(N=Nc2cnc(O)c(O)c2)cc1 +CC1(CCC2CCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21 +Cn1cc(C=C2Oc3ccc(NC(=O)Nc4cccnc4)cc3C2=O)c2c(N3CCOCC3)ccnc21 +CCCCCCCn1cc(C)c2ccc(C(=O)Nc3c(Cl)cncc3Cl)cc21 +O=C(O)C(Cc1ccc(N2C(=O)CCC(c3ccccc3)C2=O)cc1)NC(=O)C1CCC(=O)N1Cc1ccccc1 +N#Cc1ccc(CCOC(=O)N2CCN(CCCc3ccccc3)CC2)cc1 +O=C(C1C=C2c3cccc4[nH]cc(c34)CC2N(C(=O)Nc2ccsc2)C1)N1CCCC1 +COC12C=CC3(CC14CCCC4O)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +Cc1ccc(-n2nc(N3CCN(CC(C)C)CC3)cc2NC(=O)c2cnn3cccnc23)nc1 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+CC(C)(CN)COc1cccc2ccc(-c3nnc4ccccn34)nc12 +CC(OCC1(c2ccccc2)CC(N)(C(N)=O)C1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(C(=O)C(C)C)CC2)CC1OC +CCCCCn1cc([C+](c2cn(CCCCC)c3ccccc23)c2cn(CCCCC)c3ccccc23)c2ccccc21 +N=C(N)c1ccc2scc(C(Cc3ccc(N)cc3)C(=O)Nc3ccc(-n4cnc5ccccc54)cc3)c2c1 +COc1ccc(C(=O)Nc2ncccc2C)c2cc(C(C)=O)oc12 +NC(=O)c1[nH]c2ccc(Cl)cc2c1[S+]([O-])c1ccccc1 +COc1ccc2nc3c(O)n(Cc4ccncc4)cnc-3c2c1 +CC(O)c1ccc(N2CCN(C(=O)CC(N)Cc3cc(F)c(F)cc3F)CC2)cc1 +CCOC1CCC(CS)(C(=O)NC(Cc2ccccc2)C(=O)Nc2ccccc2)CC1 +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12 +Cc1cccc(N2CCN(CCCNC(=O)c3nc(C)n(-c4ccc(F)cc4)c3C)CC2)c1C +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCN(Cc2ccccc2[N+](=O)[O-])C1 +CN(C)Cc1ccccc1CNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +N#Cc1ccc2[nH]c3c(c2c1)CC(=O)Nc1ccsc1-3 +Cc1ncccc1Oc1ccc(NS(=O)(=O)c2coc3ccccc23)cn1 +COc1cc(-c2ccc(NC(C)(C)c3ccc(F)cc3)nn2)ccc1-n1cnc(C)c1 +COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)CN)c(OC)c1 +Cc1[nH]c2ncnc(Nc3cc(Cl)cc(Cl)c3)c2c1C +CCn1ccc2cnc(NC(=O)c3ccc(C(C)(O)CO)cc3)cc21 +COc1cc2cc[n+](C)c(Cc3ccc(Cc4c5cc(OC)c(OC)cc5cc[n+]4C)cc3)c2cc1OC +Cc1ccccc1C(=Cc1cc(OCc2ccsc2)ccc1Br)CO +Cn1cc(-c2cc(C(N)=O)nc3c(F)c(CN4C(=O)NC(C)(C)C4=O)ccc23)cn1 +O=C1CCCCc2cnn3c(Nc4cccc(C(=O)N5CCNCC5)c4)nc(nc23)Nc2cccc(c2)N1 +CCn1c(SCCOC)nc(NC(C)=O)c(N(CCOC)CCOC)c1=O +O=C1Nc2c(Br)cccc2C1=C1Nc2ccc(C=NO)cc2C1=NO +CCCOc1cnc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c(C)c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3n[nH]c4ccc(Br)cc34)cc(N3CCN(C)CC3)n2)c1 +COc1cc2c(cc1OC)C1=NOC(CN3CCN(CC=Cc4ccccc4F)CC3)C1CO2 +O=C(c1ccc(F)c(Cl)c1)N1CCC(F)(CNCc2ncc(C(F)F)cn2)CC1 +CCCCn1c(=N)n(CCCC)c2cc([N+](=O)[O-])ccc21 +CC(C)OCCOc1cccc(-c2cn(C3CC(CN4CCC4)C3)c3ncnc(N)c23)c1 +Cc1ccc(Nc2ncc(C(NC(=O)c3nccs3)C3CCCC3)cc2Cl)cn1 +Cc1nccn1CCC(C(N)=O)(c1ccc(F)cc1)c1ccc(F)cc1 +COc1cc(C(=O)c2sc3cc(C)ccc3c2N)cc(OC)c1OC +Cc1cc(C(N)=O)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(F)cc1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(C(CC)C(C)C(=O)O)cc1 +COc1cc(OC)cc(N(CCCN2CCCC2=O)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +COc1cc2c(=O)c(-c3cc(OC)c4c(c3OC)OCO4)coc2cc1OCc1ccccc1 +OC1CCN(c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)C1 +O=C(C(=O)N1CCCCC1)c1c(-c2ccccc2)[nH]c2ccccc12 +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)F)C(C)C +Cc1c(Nc2ccc(I)cc2F)c2c(=O)[nH]cnc2n(C)c1=O +CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3COCc3ccccc3)cc2)cc1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc4cc(NC(=O)c5ccccc5)ccc4n3)C12 +CCCCC(C)(O)C1CCCC2=Cc3c(-c4ccc(F)cc4)ncn3CC21C +NC(=O)c1cnc(N2CCC3(CC2)CCN(Cc2cccc(C(F)(F)F)c2)c2ccccc2O3)s1 +CC1=NCCc2cc(Cl)c(O)cc2N1c1ccc(C)cc1 +O=C(Nc1ccn(S(=O)(=O)c2ccc(Cl)nc2)c1)c1ccccn1 +CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1ccc(OC(CCO)CCO)c(C)c1 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cccc(O)c23)C1(C)C +O=C(NCc1cccc(-c2cccc(-c3cc4c[nH]ccc-4n3)c2O)c1)Nc1ccccc1Cl +CC(=O)Nc1ccc(OC(=O)CNC(=O)C(C)c2ccc(Nc3ccnc(C(F)(F)F)c3)cc2)cc1 +CC(=NNC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1)c1ccccc1O +CCNS(=O)(=O)c1ccc(NC2CC3CCC2C3)c(NCc2ccncc2)c1 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+O=C(Cc1cccc(F)c1)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12 +NC1CC(N2Cc3nn4ccc(C(F)(F)F)nc4c3C2)COC1c1cc(F)c(F)cc1F +Cc1nc(Cl)c(-c2cc(C(=O)N3CC(c4ccc(C#N)cc4)C3)c(C)cc2C)[nH]1 +COC(=O)C1CC(O)CN1C1(c2ccccc2)C(=O)Nc2ccc(-c3c(C)noc3C)cc21 +COC(=O)c1ccc(CN2CCC(Nc3nc(Oc4c(C)cc(C#N)cc4C)c4sccc4n3)CC2)cc1 +CC(C)c1cccc(C2CNCC2C(=O)Nc2cc3cc[nH]c(=O)c3cc2Cl)c1 +O=C(Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1)Oc1ccccc1 +O=C(COc1cccc2occ(S(=O)(=O)c3ccc4ccccc4c3)c12)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +CC1COCCN1c1nc(N2CC3COCC3C2)nc2[nH]c(-c3cccc4[nH]ccc34)nc12 +N#Cc1ccc2cc1Oc1ccc3cccc(c3c1)N1CCC(NCCc3cncn3C2)C1=O +Cc1ccc2c(c1)[nH]c1c2ccc2c(C=O)c[nH]c21 +O=C(NO)c1cnc(NC2(c3cccc(C(F)(F)F)c3)CC2)nc1 +CN(C)C(=O)C1C(c2ccc(Cl)cc2)CC2CCC1N2CCCF +N=C(N)NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(-c3nc(N4CCOCC4)c4cccnc4n3)cc2)cc1 +COc1nccc2[nH]nc(-c3ccnc(N4CC5CC4CO5)c3)c12 +COc1cc(Nc2ccc(S(=O)(=O)NCC3CCCO3)cc2F)cc(OC)c1 +COc1cc2c(Oc3ccc(NC(=O)c4nccc(-c5ccc(C)cc5)n4)cc3F)ccnc2cc1OCCCN1CCCCC1 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+CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1c(F)cccc1F +Cc1ccc(-c2cc(C(=O)NC(C)c3cnccn3)cc(N(C)C(=O)C(C)(C)C)c2)cc1 +CC(OC1CCC(N(C)Cc2n[nH]c(O)n2)C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(CO)(CO)n1cc(-c2cc(F)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +CNC(=S)Nc1ccc(OCCn2c3ccccc3c3ccccc32)cc1 +O=C(CCl)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1 +Cn1nncc1-c1cnc(N)c(-c2ccc(C(=O)NC(CO)c3cc(F)cc(C(F)F)c3)c(F)c2)c1 +Cc1cc(Nc2nc(OC(C)c3ncc(F)cc3F)c(F)c(N3CCOCC3)n2)n[nH]1 +CCCCCn1cc(C(=O)NN2CCCCC2)c(=O)c2cc(Br)ccc21 +Cc1cc(N2CCC(N3CCCC3C)C2)ccc1NC(=O)c1ccc(Oc2nccs2)cc1 +O=C(NCC(c1ccccc1)n1ccnc1)c1ccc(C=Cc2ccc(F)cc2)cc1 +Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2cc(C3CC3)nn12 +N#Cc1ccc(CN2CCC(N(N)CC(=O)N3CSCC3C#N)CC2)cc1 +CC(C)(C)c1cc(C2=Cc3ccc(C(=O)O)cc3OC2)cc(C(C)(C)C)c1O +COc1ccccc1N1CCN(CC2COC3(CCN(C(=O)c4ccc(C(F)(F)F)cc4)CC3)O2)CC1 +COc1cnc(N2CCOCC2)c2sc(NC(=O)C(C)(C)Oc3ccccc3F)nc12 +O=C(Cc1ccccc1)Nc1nc(-c2ccccc2)nc2cn(-c3ccccc3)nc12 +Cc1cc(Oc2cc(F)cc(CNC(=O)c3ccc(C(F)(F)F)cc3F)c2)ccc1OC(C)(C)C(=O)O +COc1cccc(N2C(=O)C(=Cc3ccc(OCC(=O)Nc4cccc(C)c4)cc3)N=C2c2ccccc2)c1 +COc1cccc(F)c1-c1cc(NC(=O)C2CCCNC2)ncn1 +O=C(Nc1cn2nc(-c3cn(C4CC4)nc3-c3ccc(F)cc3)ccc2n1)c1ccncc1F +O=C(NC1CCC(CCN2CCN(c3nsc4ccccc34)CC2)CC1)N1CCOCC1 +Cc1ccc(-n2nc(C3CCN(C4CCC(C#N)CC4)CC3)cc2NC(=O)c2cnn3cccnc23)cc1 +CC1C2CCC3C4CC=C5CC(N(C)S(=O)(=O)N(C)C)CCC5(C)C4CCC32CN1C +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccc(Cl)c(Cl)c4)nc23)N1 +COc1cc(N2CCN(C(=O)C(C)N)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +O=C(NC1(c2ccccc2)CCC1)C1CCCC1c1cc(-c2cccc(C(F)(F)F)c2O)on1 +COc1ccc(C=CC(=O)c2cccc(Nc3nc(-c4ccc(OC)c(OC)c4)nc4ccccc34)c2)cc1OC +Cc1cn(CCCc2ccccc2)c2cc(C(=O)Nc3c(Cl)c[n+]([O-])cc3Cl)ccc12 +CCCCc1ccc(C(=O)Nc2cccc3ccc(O)cc23)cc1 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc2ccccc2c1C(=O)c1cccc(Cl)c1 +c1cnc(Oc2ccc(Nc3nc4ccccc4s3)cc2)c(C2CCCCO2)c1 +N#Cc1cc(-c2ccnc(Nc3ccc(NC4CCNCC4)nc3)n2)cnc1N1CCC(F)C1 +Cn1cc(-c2cnn3c(N)c(-c4ccc(NC(=O)Nc5cccc(C(F)(F)F)c5)cc4)cnc23)cn1 +COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)c3cccc(F)c3)cc2)cc1 +CC(CS)C(=O)N(CC(=O)O)C1CCC(c2ccccc2)CC1 +O=C(c1cc2c(cc1F)OC(c1ccc(F)cc1F)(c1ccc(F)cc1F)O2)N1CCOCC1 +COc1ccc(C=CC(=O)NC(=S)NNC(=O)c2cnccn2)cc1 +CS(=O)(=O)N1CCN(Cc2cn3cc(-c4ccc(N)nc4)nc(N4CCOCC4)c3n2)CC1 +Cc1cc(C2=C(c3ccc(O)c(C)c3)C3C(S(=O)(=O)Oc4cccc5ccccc45)CC2[S+]3[O-])ccc1O +CC(=NNC(=O)C(Cc1ccccc1)NS(=O)(=O)c1ccc(C)cc1)c1ccccc1 +Nc1nc(-c2sc3nc4c(cc3c2N)CCCC4)nc(N2CCOCC2)n1 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1NC(=O)c1cnc2[nH]ccc2c1 +CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)c1ccccn1 +CCNCC(Nc1ncnc2c(C(N)=O)cccc12)c1ccccc1 +CC(=NOCC(C)C)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)-c1cn(C)nc1CC4 +NC(CC(=O)N1CCn2c(nnc2C(F)(F)C(F)(F)F)C1)Cc1cc(F)c(F)cc1F +OC(CNC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1)COc1ccccc1 +Cc1cc(C)cc(-c2cnc3cc(Cl)c(-c4ccc(F)nc4)cc3c2OCCC2CCCCN2)c1 +CC(=O)c1ccccc1-c1ccc2[nH]c(C=Cc3ccc(C(F)(F)F)cc3)nc2c1 +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4ccc(N)cc4)cc3)nc2c1 +OCC#Cc1cncc(-c2cnc(Nc3cc(N4CCOCC4)ccn3)s2)c1 +Fc1ccc(NCC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)c(C(F)(F)F)c1 +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCc4ccc(C#N)cc4)c3C(C1)C2 +Cn1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CC(O)(CN)C3)n2)cn1 +Cc1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)C3)c2)c1 +COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(C(=O)N4CCN(C)CC4)cn3)c3nccnc23)c1Cl +N=C(N)c1ccc(C2C3C(=O)N(Cc4ccccc4)C(=O)C3C3CCCN32)cc1 +CC(=O)N1CCC(CNC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 +COc1ccc2nccc(NC(c3cccc(Cl)c3)c3ccc(CN4CCOCC4)c(Cl)c3)c2c1 +Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2Cl)n1 +CCNC(=O)OCc1c(COC(=O)NCC)c2n(c1C)Cc1c(c3ccccc3n1C)C2 +CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCc3cccc(F)c3)c2)NC(=O)N1 +Cc1ccc2c(c1)COP(=O)(OCC1C=CC(n3cc(C)c(=O)[nH]c3=O)O1)O2 +OC1CCC(Nc2nc(Cc3ccccc3)cc(Nc3nc4ccccc4s3)n2)CC1 +CC(C)c1nc2c(c(Nc3ccc(Oc4ccccc4)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +O=C1CC23CCN(CC4CC4)C(Cc4ccc(O)cc42)C3(O)CC1CCO +Cc1cc(-c2c(F)cccc2F)cc2nnc(Nc3ccc(OCCN4CCCC4)cc3)nc12 +O=C(NCc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1)c1ncccn1 +CN1CCN(CCCNC(=O)C2C(C(=O)NCc3ccc(Br)cc3)C3C=CC2C32CC2)CC1 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+COc1cccc(-c2ccc3c(c2)CN(C(C)=O)c2ccc(Cl)cc2CC3)c1 +O=C(CCCCCCc1nc2ccc(-c3ccccc3)cc2[nH]1)NO +CN(CCc1cccc(S(=O)(=O)CCO)c1)C(=O)CCCn1nnnc1C(COCc1ccccc1)NC(=O)C(C)(C)N +Cc1ccc(Nc2nc3c(N4CCCC4)ncnc3s2)cc1 +[O-][n+]1ccc2c(-c3ccccc3Cl)ccnc2c1-c1c(Cl)cccc1Cl +CCOC(=O)c1c(C=O)[nH]c(C(=O)OC(C)(C)C)c1CC +O=C(CCCSCCC1NCC(O)C(O)C1O)N1CCOCC1 +COc1cc(OC)cc(N(CC#Cc2nccs2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1nc2c(cnn2-c2cccc(S(N)(=O)=O)c2)c(=O)n1-c1ccc(Cl)cc1 +COc1ccc(C2c3c(ccc4ccccc34)OC3N=CN(CCN4CCOCC4)C(=N)C32)cc1OC +OC1=C2C(=Nc3ccccc3SC2c2ccco2)c2ccccc21 +CCc1ccccc1CNCC(C)C(=O)N(Cc1cc(Cl)c2c(c1)OCCCO2)CC(C)C +CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1nc3ccc(Cl)cc3s1)c1c(O)cc(F)c(Cl)c12 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(CSC)c4ccccc43)CC2)C(C)C)c1 +Cc1ncc(C(CNC(=O)c2cccc(Cl)c2Cl)CC2(C(F)(F)F)CC2)cn1 +CCOC(=O)c1cnn(-c2ccc(C(=O)N(C3CC3)C3CCN(C(=O)OC(C)(C)C)CC3)cc2)c1C +CNC(=O)c1nc(-c2ccc(Cl)c(S(=O)(=O)Nc3cccc(F)c3Cl)c2)cnc1N +CCCCCCNC(=O)Oc1ccc2c(c1)C1(C)CCN(CC)C1C2 +O=c1n(-c2ccc(F)cc2)ccc2nc(COc3cccc(F)c3)cn12 +COc1ccc(C(O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2F)cc1 +Cc1cn(-c2ccc3n(c2=O)CCN(C2CC(Oc4ccccc4C(F)(F)F)C2)C3=O)cn1 +Cc1c([N+](=O)[O-])nc2c(c1C(N)=O)c1ncnc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c1n2C +Cc1cn(-c2ccnc(Nc3cc(C)c(OCC(=O)N4CCCC4)c(C)c3)n2)cc1CN1CCC(O)C1 +O=C(Nc1ccccc1-n1cccc1)C1CCCN1C(=O)CCc1nc2ccccc2[nH]1 +COc1cc(-c2ccccc2Cc2nc3c(cnn3C3CCOCC3)c(=O)[nH]2)ccn1 +COC(=O)c1ccc(CCCN2C(=O)C(F)(F)CC2C=CC(O)C(C)Cc2ccccc2)s1 +O=c1nc(NN=Cc2cccc(Cl)c2)c2cn[nH]c2[nH]1 +CC(C)C(NC(=O)c1ccc(-c2ccc(NC(=O)Nc3ccccc3OC(F)(F)F)cn2)cc1)C(=O)O +Cc1cnc(C(=O)N2CCCC(Nc3cnc(C(F)(F)F)cn3)C2C)c(-c2ncco2)c1 +Cc1ccn2nc3c(c2n1)CN(C1CCC(c2cc(F)c(F)cc2F)C(N)C1)C3 +Nc1nc(-c2ccco2)c2cnn(Cc3ccccc3F)c2n1 +Cc1ccc(C(=O)C=Cc2cccc(C(F)(F)F)c2)o1 +CC1(C)CCN(C2C3CC4CC2CC(O)(C4)C3)C(=O)c2cnn(-c3ccc(F)cc3)c21 +NC(=O)c1cccc(-c2[nH]nc3cc(Nc4ccccc4Cl)ccc23)c1 +Nc1ccc(CNCc2ccc(CN3CCCNCCNCCCNCC3)cc2)cc1 +O=C(Cn1ccc(-c2ccc(C(=O)NO)s2)n1)Nc1cc(F)cc(F)c1 +COc1ccc(NC(=O)c2cccc3c(Br)cccc23)cc1 +O=C(CCCCCCC(=O)Nc1cccc(-c2cn(C3CCCCC3)nn2)c1)NO +O=C(CN1CCOCC1)NC1CCC(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +OCc1cc(C(O)CNCCc2ccc(Nc3ccc(O)cc3)cc2)ccc1O +CCCCNC(=O)C1CCC(c2nc3c(=O)n(CCC)c(=O)n(CCC)c3[nH]2)CC1 +O=C(O)CCCNC(=O)C(Cc1ccc(-c2ccccc2)cc1)NCP(=O)(O)O +CC1CCCN1C1CCN(c2ccc(N3CCCC4(CCN(CC5CC5)CC4)C3=O)cc2)C1 +CCCCCCCCCCCCOC(=O)C(C(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccn1 +O=S(=O)(c1cccc(C(F)(F)F)c1)n1c2c(c3ccccc31)CCNCC2 +CC1(C)CCN(C2C3CC4CC2CC(O)(C4)C3)C(=O)c2cnn(-c3ccccc3)c21 +Cc1[nH]ncc1-c1cc(Cl)ccc1Oc1ccc(S(=O)(=O)Nc2nccs2)cc1C#N +CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C(=O)N1CCCCO1 +Cc1c(C)c2c(c(C)c1O)C(CN1CCN(c3ncccn3)CC1)C(C)(C)O2 +CCOc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2n1 +CCOc1cc(C2NC(=O)NC(c3cccnc3)=C2c2ccccc2)cc([N+](=O)[O-])c1O +CSC(=NC#N)N1CCC(CCN2C3CCC2CC(n2c(C)nc4ccccc42)C3)(c2ccccc2)CC1 +CCN(CC)CCCC(C)Nc1c2c3ccccc3nc-2n(C)c2ccc(Cl)cc12 +CCOC(=O)c1ccc(N(C=Nc2ccn(C3CSC(CO)O3)c(=O)n2)c2ccc(C(=O)OCC)cc2)cc1 +Cc1nc(-c2c(F)cc(Cl)cc2-c2cnc(C(C)NC(=O)C3(NC(=O)c4cncnc4)COC3)c(F)c2)no1 +Cc1cc(C=Cc2ccc3cc(N(C)C)ccc3[n+]2C)c(C)n1-c1ccccc1 +CCN(CC)C(=O)CN1C(=O)C(NC(=O)Nc2cccc(OC)c2)N=C(c2ccccc2)c2ccccc21 +COC(=O)c1ccc(Oc2ccc3c(c2)B(O)OC3)cn1 +CCOc1ccc(-c2nc(-c3ccc4c(c3)CCC(=O)N4)cs2)cc1OCC +COc1ccc(CN(c2ccc(C#N)cc2)n2cnnc2)cc1O +Cc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(F)(F)F)cc1 +CCCc1c[nH]c(C2Cc3cc(OC)ccc3N2C(=O)C(C)N)n1 +CN(C)CCN1C(=O)c2c(c3c4ccccc4[nH]c3c3cc4ccccc4cc23)C1=O +Cc1c(C(=O)NCCCN2CCN(C)CC2)cc(-c2ccc3ccccc3c2)n1-c1ccc(S(N)(=O)=O)cc1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)C(=O)NC1c2ccccc2CC1O +CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(-c2cccc(C#N)c2)cc1)C(=O)O +CC(C)CC1CNC(C(=O)NCCCCCC(=O)NO)Cc2ccc(cc2)OCCCCCC1C(=O)OC(C)(C)C +COc1ccc(-c2nc3c(OCC4CCNCC4)c(Cl)cnc3[nH]2)cc1 +CC(C)Nc1ncc(-c2cc(-c3ccccc3Cl)nc(-c3ccccn3)n2)s1 +CCCc1cc(-c2nc(C)c(C(=O)N(C)C)s2)ccc1OCCCOc1ccc2c(c1)CCC2CC(=O)O +OCC(O)CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCc3ccccc3)c2)[nH]1 +COC1COCCC1NC1CC2SCCC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +Cc1cc2c3c(c1)C(c1ccccc1)=NC(NC(=O)c1ccc(Cl)cc1Cl)C(=O)N3CC2 +CCCc1c(CC=C(C)CC=CC(C)C)[nH]c(=O)c(C)c1O +Cc1cc(Nc2ccnc3cc(Cl)ccc23)cc(CNC(C)(C)C)c1O +O=C(O)CCCCC=C(c1ccc(-c2nc(C(=O)NCCCCOC3CCCCC3)co2)cc1)c1cccnc1 +Cn1ncc2c(Nc3ccc(F)cc3)nc(N3CCN(c4ccc(F)cc4)CC3)nc21 +O=C(CC(CCCC1CCCCC1)c1nc(-c2cc(C(=O)O)ccn2)no1)NO +CC(C)n1cc(C(=O)c2cc(NC(=O)Cc3ccc(Cl)cn3)ccn2)c2cnccc21 +O=[N+]([O-])c1ccccc1C=Nc1nc2ccccc2s1 +Oc1cccc(CCN(CCc2ccccc2)CC2CCCCC2)c1 +COc1n[nH]c2cc(NC(=O)NC(c3ccc(F)cc3)C(C)O)nc(CO)c12 +C=CCN1CC(C)N(C(c2ccc(C(=O)NC(C)(C)C)cc2)c2cccc(OC)c2)CC1C +O=C(NCC1CCNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 +COc1ccc(C=CC(=O)c2ccc(OC)c3c2OC(C)(C)C=C3)cc1NCc1ccccc1 +CCC(C)(C)C(=O)Nc1ccc(N2CCN(C(=O)c3ccccc3)CC2)c(Cl)c1 +COc1ccc(C#N)cc1NC(C)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +O=S(=O)(NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1)N1CCOCC1 +CC(C)(C)Nc1cnc2cccc(-c3cc4n(c3)CCNC4=O)c2n1 +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)CC3CC3)ncc2c1 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+O=C(NCc1nc2ccccc2[nH]1)C1=CC(c2ccc(Br)cc2)CC(OCCCCO)O1 +Cn1ccc2cc(-c3ccc4oc(Cc5ccccc5)nc4c3)ccc21 +Cn1cc(-c2ccc3c(c2)C(=O)c2c-3[nH]c3cc(C#N)ccc23)cn1 +O=C1NC2(CCCc3ccccc32)C(=O)N1CCCN1CCN(c2ccccc2)CC1 +O=C1C(=Cc2ccc(Oc3ccc(Cl)cc3)cc2)Oc2ccccc21 +COc1cc(C)cc(-c2c(-c3cc(NCC(C)O)nc(-c4cccnc4)n3)cnn2C)c1 +CNC(=O)c1ccccc1Nc1nc(Nc2cccc3c2OCCO3)nc2c1CCN2 +Cc1cc2ncn(-c3nc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)c2cc1C +CNC(=O)NC(C)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 +COc1ccc(OC2CN(C(C)c3nc4c(cnn4C4CCCC4)c(=O)[nH]3)C2)cc1 +Nc1n[nH]c2c1c(Nc1ccc(F)cc1)nc1ccccc12 +CNC(=O)Cn1cc(-c2cc(F)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +N#Cc1c(O)nsc1Nc1cc(Br)cc(C(F)(F)F)c1 +N#CCc1c(C(=O)N2CCC(c3ccc(F)cc3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +O=c1c2cc(Cl)ccc2nc(-c2ccccc2O)n1CCc1ccccc1 +CN1CCN(CCC(=O)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)CC1 +N=C(Nc1ccc2c(c1)CCN2C1CCNCC1)c1cccs1 +CN(CC(N)=O)C1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +COc1cccc(-c2cnc3nc(C(F)(F)F)ccn23)n1 +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1ncccc1OCc1ccccc1 +CNc1nc2cc(-c3cccc(CNS(N)(=O)=O)c3)sc2n2c(C)cnc12 +CCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ccnc(NCC(F)F)c4Cl)C3)cc2)s1 +Cc1cccc(Cl)c1CNC(=O)c1cn2cc(-c3ccc(C4CCC(C(C)(C)C(=O)O)CC4)cc3)ccc2n1 +Cc1cccc2cc(Cn3nc(-c4ccc(F)c(O)c4)c4c(N)ncnc43)n(C3CCCC3)c(=O)c12 +COc1ccc(S(=O)(=O)n2c(C)c(C(=O)N3CCCN(C)CC3)c3ccccc32)c(C)c1C +CCCc1cnc(N2CCC(Oc3cc(=O)n(-c4ccc(S(C)(=O)=O)cc4)cc3C#N)CC2)nc1 +COc1ccc2[nH]nc(C(=O)NCC3CCN(Cc4ccccc4)CC3)c2c1 +Cc1ccc(C(=O)Nc2cc(-n3ccnc3)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCOCC3)nc12 +CCc1cn(C2CC(O)C(CNC(=O)Cc3c(Cl)cccc3Cl)O2)c(=O)[nH]c1=O +Cc1ccc(C)c(Sc2ccc(Nc3cc(S(=O)(=O)O)c(N)c4c3C(=O)c3ccccc3C4=O)cc2)c1 +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(OC)cc1)C(=O)c1cc(Cl)cc(Cl)c1 +COc1cc(Br)cc(C(=O)NC2CCN(Cc3ccccc3)CC2)c1OC +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1c2cc(Cl)ccc2-c2n[nH]cc2C1C1CC1 +CN1C(=O)CCc2ccc(NC(=O)NC3CCOc4c3cccc4C(F)(F)F)cc21 +CCCOc1ccc(-c2nc(C)c(C(=O)O)[se]2)cc1C#N +NC(CSC(C=CC=CC=CCC=CC1CCCCC1)C(O)CCCC(=O)O)C(=O)O +N=C(N)c1ccc2oc(-c3cccc(OCCCCCCOc4ccccc4)c3)cc2c1 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+O=C(c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1cnc(N2CCNCC2)nc1)C1CC1 +CSc1nn2cc(-c3nc4ccc(OCc5cc(F)cc(F)c5)cc4o3)nc2s1 +O=C(NC(Cc1ccccc1)C(=O)NC1C(=O)N2CCOC12)OCc1ccccc1 +CCC1CN2CCC34c5ccccc5N5C=C6C7CC8N(CCC89c8ccccc8N(C=C(C1CC23)C54)C69)CC7CC +C=CCNc1nc(N2CCC(NCC3c4ccccc4CCc4ccccc43)CC2)c2ncn(CC=C)c2n1 +CNC(=O)C(NC(=O)C(CCCCOc1cccc(C)c1)CC(=O)NO)C(C)(C)C +CC(C)CNCc1ccc(-c2ccccc2S(=O)(=O)N2CCC(F)(F)C2)cc1 +O=C(NCc1cccc(Cl)c1)C(=O)c1c[nH]c2ccccc12 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(C=CC(N)=O)cccc3nc2-1 +Nc1nc2cc3c(cc2s1)CC1C2CCCCC32CCN1CC1CCC1 +O=C(O)CCC(NC(=O)Sc1cc[n+]([O-])cc1)C(=O)O +CCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O +NCCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccc2ccccc2c1)NC(=O)c1ccc(CN)s1)C(N)=O +CC(c1ccc2[nH]c(=O)sc2c1)c1ccn(-c2ccccn2)n1 +CCOc1ccc2c(c1)CCN(c1ccc(C(=O)Nc3cccc(C)n3)cn1)C2 +Fc1cccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1F +COc1cccc(N2CCN(C3=Nc4c(F)cccc4C(CC(=O)O)N3c3cc(C(F)(F)F)ccc3OC)CC2)c1 +O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cn2ccnc2)c1 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+CC(c1ccc(C(F)(F)F)cc1)n1c2c(c3cc(F)cc(S(C)(=O)=O)c31)CCCC2CC(=O)O +CN(C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)C1CCN(C(=O)N(C)C2CCNC2)C1 +CC1(C)C=C(c2cccc[n+]2[O-])c2cc(C(F)(F)C(F)(F)F)ccc2C1=O +CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2Cc2c(C)noc2C)n1Cc1ccc(C(=O)OC)cc1 +Cc1ccc2[nH]c(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)c(F)c3)nc2c1 +c1cc2[nH]nc(-c3ccc4c(c3)OCO4)c2cc1-c1nnn[nH]1 +Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)C3CCC(F)(F)C3)CC2)n1 +CC(C)(C)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)NO +CC(OC1CN2C(=O)C=CCC2C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(C(N)=O)nc3)nc2n1 +CC(N)P(=O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O +CCOc1ccccc1-c1cc(C(=O)NCc2ncccc2C)nc(N)n1 +CCCc1cc(C(=O)c2ccc(F)cc2)ccc1OCCCOc1ccc2c(ccn2CC(=O)O)c1 +CC1(O)C(O)C(CO)OC1n1cnc2c(=O)[nH]c(N)nc21 +COc1cc(-c2ccc3c(c2)NC(=O)C3=Cc2ccc[nH]2)ccc1O +CCCC1(O)CCOC(C(=O)NC(Cc2ccccc2)C(O)CN(CC(C)C)S(=O)(=O)c2ccc(OC)cc2)C1 +CCOc1nccc(Br)c1C(=O)N1C2CCC1C(COc1ccccn1)C2 +CN(C)CCCON=C1c2ccccc2-c2nc3c(C(=O)NCCN4CCCC4)cccc3nc21 +CC(C)(C)OC(=O)N1CC2CC(Oc3ncnc(Nc4ccc(S(C)(=O)=O)cc4F)c3[N+](=O)[O-])C1C2 +CC(=O)N1CCN(C2CCC(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 +O=CC(Cc1ccccc1)NC(=O)C1CCCN1S(=O)(=O)c1ccccc1 +CC(CC(=O)OCC1(CO)CC(=Cc2ccccc2C(F)(F)F)C(=O)O1)CC(C)(C)C +COC(=O)c1cccc2c1c(C(=O)c1ccc(Cn3c(C)nc4cccnc43)cc1)cn2C(=O)N(C)C +C#Cc1cc2c(cc1N1CCN(C3CCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CCCN(CCC)Cc1ccc(-c2ccc(CN3CCCCC3)cc2)cc1 +O=C(Nc1ccc(CC2CCC(C(O)c3cccnc3)N2)cc1)C1CCc2scnc21 +CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(F)cc2)c1=O +CCCCOC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 +O=C(Cc1ccc(Cl)cc1)NCc1ccc(-c2nc(C(=O)N3CCCCC3)co2)cc1 +CC(F)(F)c1cccc(NC(=O)Nc2ccc(Oc3cc(NC(=O)C4CC4)ncn3)c(F)c2)c1 +NC(=O)OC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(CC(O)C(F)(F)F)c1=O)c1cccc(Cl)c1Cl +CN(CCCNc1ccnc2cc(Cl)ccc12)Cc1cc(=O)c(OCc2ccccc2)cn1C +CCC(=O)CCCCCC1NC(=O)C2CCCN2C(=O)CC(CC(C)C)NC(=O)C(Cc2c[nH]c3ccccc23)NC1=O +Cc1ccsc1C(=CCCN1CCCC(C(=O)O)C1)c1sccc1C 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+COc1ccc(C)n2nc(CCc3c[nH]c(-c4ccccc4)n3)nc12 +CCCCCCN=c1ccn(Cc2ccccc2Cl)c2cc(Cl)ccc12 +CN(C(=O)N1CCC(n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)C1)C1CCN(C2CCC(C)(C)CC2)C1 +CN(C)C(=O)c1ccc(N(Cc2ccc(F)cc2)C(=O)c2cc(Cl)c(O)cc2O)cc1 +Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCCCCn2ccnc2)cc1 +CCCCCCNC(=O)NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Oc1ccc(C)cc1 +CCn1c(=O)n(-c2cnn(Cc3c(C)noc3C)c2)c(=O)n1Cc1ccccc1 +CC(Sc1cc(-c2cnn(C)c2)cnc1N)c1c(Cl)ccc(F)c1Cl +CC(Nc1c(-c2c(F)cc(OCCCCO)cc2F)c(Cl)nc2ncnn12)C(F)(F)F +O=C(NC(CCc1ccccc1)C(=O)c1ncco1)C(CC(=O)N1CCOCC1)CC1CCCCC1 +N#Cc1ccc2[nH]cc(C3CCC(N4CCN(c5cccc6[nH]ccc56)CC4)CC3)c2c1 +COc1cc(C)cc(-c2ccc(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)c(OC)c2)c1 +COc1ccc(Cc2cnc(N)nc2N)cc1OS(C)(=O)=O +C#CCOCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(C)=O)c1 +CN1CCC(N(C)C(=O)c2cn(C)c(=O)c3[nH]ccc23)CC1 +CS(=O)(=O)CCCCC1(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)CCCC1 +Cc1ccc(C=CC(=O)O)c(OCCC2(C)CCc3c(C)c(O)c(C)c(C)c3O2)c1 +CC(C)CCOc1c(C(=O)c2ccccc2)c[nH]c2nncc1-2 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+CCN(CC)CCCOC(=O)c1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O +COc1c(Cl)cc(N2CCN(CC3CC3c3ccccc3)CC2)cc1Cl +CC(C)(O)COCc1cccc(Nc2sc(-c3c(F)cc(C(C)(C)O)cc3F)cc2C(N)=O)n1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(C2CC2)c1 +CCSC(=S)SCC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +O=C(CN1CCN(Cc2ccc(Cl)cc2)CC1)N1CCc2c(F)cccc21 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(N=CN(C)C)ccc3nc2-1 +COc1ccc2c(C3CCc4ccc(Cl)cc43)ncnc2c1OC +O=C(Nc1ccccc1C(=O)Nc1ccc(CCN2CCc3ccccc3C2)cc1)c1cnc2ccccc2c1 +NC1CCCCC1Nc1cc2cn[nH]c(=O)c2c(Nc2cccc3cc[nH]c23)n1 +COc1cc2c(cc1OC)C1=NOC(CN3CCN(Cc4ccc5ncccc5c4)CC3)C1CO2 +CN1CCC(Nc2ccc(Nc3nccc(-c4ccc(N5CCC(F)(F)C5)c(C#N)c4)n3)cn2)CC1 +CC(C)c1cc(C(=O)N2Cc3ccc(OCCN(C)C)cc3C2)c(O)cc1O +NS(=O)(=O)c1ccccc1-c1ccc(C(=O)NC(CC(=O)Nc2ccc(Br)cn2)C(=O)N2CCCC2)cc1 +NS(=O)(=O)c1ccc(-c2nnc3sc(-c4ccc(F)cc4)nn23)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(COCC4CC4)c4ccccc4)ncc23)no1 +Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2cc(Cl)ccc2Cl)cc1 +O=C(c1nc2ccccc2[nH]1)N1CC(c2ncc(F)cc2-c2ccccc2)C1 +CS(=O)(=O)Nc1ccc(CCNC(=O)c2ccnc3[nH]c(-c4cccs4)nc23)cc1 +O=C1C(=O)N(c2cccc(Cl)c2Cl)CCN1Cc1cccc(Cl)c1 +CC1CN(c2nc(Nc3ccncc3)nc(NC3Cc4ccccc4C3)n2)CCN1 +O=C(NC1COCCC1NC1CCOCC1)c1ccc(C(F)(F)F)cc1C1CC1 +Cn1nc(-c2ccc(C(N)=O)cc2)sc1=NC1CCCC(O)C1 +CC(=O)N1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +CCOc1ccccc1OCCN1CCN(c2cnn(CCCCN3CCN(c4ccccc4OC)CC3)c(=O)c2Cl)CC1 +CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)nn3-c3ccc(S(C)(=O)=O)cc3)ccc21 +COc1ccc(-c2c(N)ncnc2N2CCC(c3nc(-c4cccc(C(F)(F)F)c4)c[nH]3)CC2)cc1 +O=S(=O)(CCO)N1CCCC2CN3CCc4ccccc4C3CC21 +CCCC(=O)NCCc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +CCOC(=O)CC(NC(=O)c1cccc(COc2cc(O)c(C(C)=O)cc2CC)c1)C(=O)OCC +CCCCCCCCCCCCCCCCOCCCOP(=O)(O)COC(CO)Cn1cnc2c(N)nc(N)nc21 +COc1cccc(Nc2cc(C3CC3)nc3c2C(=O)NCC3)c1 +Cc1cc(-c2cccc3cc[nH]c23)c(F)c2c1NC(C)(C)C(O)C2C +C=CC[n+]1ccccc1C=c1sc(=C2Sc3ccccc3N2C)c(=O)n1C +CN(C)CC(=O)Nc1cc(-n2cccn2)nc(-c2ccco2)n1 +Cc1noc(-c2cc3cc(-c4cc(C(=O)NCc5cnn(C)c5)nn4C)ccc3[nH]2)n1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCN(S(C)(=O)=O)CC4)cc3OC)ncc2Cl)c1 +C#Cc1ccc2c(c1)C(=O)N1CCC1c1c(-c3nc(C(C)C)no3)ncn1-2 +COc1cc(C)cc2cc(-c3c(CNCC(=O)O)c(CN4CCNCC4)n4ncnc(N)c34)sc12 +CC1(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)CC(c2ccc3ccccc3c2)=NO1 +CNCc1cc(C(=O)N2CCCN(C3CC3)CC2)ccc1Oc1ccc(C#N)cc1 +O=C1C2Cc3ccccc3CN2C(=S)N1CCN1CCCCC1 +COc1cc(-c2cc(F)cc(Cl)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3cccnn3)ccc21 +CN1CCC(c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C4CC4)cc3F)n2)CC1 +Cc1nn(Cc2ccc(NC(=O)CCc3ccccc3)cc2)c(C)c1CC(=O)O +Oc1ccc2ncnc(Nc3ccc(OCc4ccccc4)cc3)c2c1 +O=C(Cn1cnc2ccccc21)N1CCN(c2scnc2-c2nc3ccccc3[nH]2)CC1 +COCCCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCF +Nc1ncc(C2CCOC2)nc1-c1ccc(C(=O)NC(CO)c2ccccc2)cc1 +NCC1CCCC(CNC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)N2CCC3(C=Cc4ccccc43)CC2)C1 +Cc1ccc(Nc2ccc(Oc3ncccc3C3CCN(S(C)(=O)=O)CC3)cc2)nc1 +Cn1cc(Br)c(C(=O)N2CCN(CC(=O)c3ccc(C(F)(F)F)cc3)CC2)n1 +CC(C)(OCc1cc(Cl)cc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1)C(F)(F)F 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+COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)[nH]c3ccc(C)cc23)CC1 +CC(C)C1CCC(C)C2(C1)OOC1(CC(C(C)C)CCC1C)OO2 +O=C(NC1CCNCC1)c1cc(-c2c(O)cc(O)cc2Oc2ccc([N+](=O)[O-])cc2)on1 +Nc1nccn2c(-c3cccc(NC(=O)c4cc(F)cc(F)c4)c3)cnc12 +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)c(C)n1C)CC2 +COCC(C)Oc1cc(C#Cc2ccccc2OC)cc(C(=O)Nc2ccn(C)n2)c1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC#CCN4CCN(c5cccc(C(F)(F)F)c5)CC4)c3)nc2n(CCC)c1=O +CNC(=O)OC(CC(C)NC(=O)Nc1cccc(-c2nnnn2C)c1)N1CCCC(Cc2ccc(F)cc2)C1 +Cc1ccc(C=NOCc2ccc(-c3cccc(C(F)(F)P(=O)(O)O)c3)cc2)o1 +CSc1nn(-c2ccc(C)cc2)c2cc(C3=CCNCC3)ccc12 +CCOc1ccc(Nc2nc(C)nn(C(C)C3CC3)c2=O)c(C(F)(F)F)n1 +O=C(O)CN1C(=O)C(=Cc2ccc3ccccc3c2)SC1=S +CC(C)c1cccc(C2CCN(C(=O)C3CCC(CC(=O)N4CCCCC4)CC3C(=O)NO)CC2)c1 +Cc1ncccc1Oc1ncnc(OC2CC3CC(=O)C(C2)N3S(=O)(=O)C2CC2)c1C +CS(=O)(=O)Cc1ccc(-c2ccc3c(Nc4ccccc4)c(C(N)=O)cnc3c2)cc1 +N#Cc1cccc(S(=O)(=O)c2sc3ncc(N)cc3c2-c2cccc(Cl)c2)c1 +O=c1[nH]c(CN2CCN(c3cccc(O)c3)CC2)nc2ccccc12 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+CN(Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1)c1ccccc1 +CCCC1(C)SC(NC23CC4CC(CC2C4)C3)=NC1=O +CC(C)(C)N(NC(=O)c1ccccc1F)C(=O)c1ccccc1Cl +O=C1CC2(CCCC2)CCN1OCCCN1CCN(c2nsc3ccccc23)CC1 +CNS(=O)(=O)c1ccc(NC=C2C(=O)Nc3ccccc32)cc1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2ccccc2-c2csnn2)n1 +CCN1CCCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(F)c(Cl)c3)CC2)nc1 +Cc1ccc(C2c3c(C)c(N)c(C)c(C)c3OC2(C)C)cc1 +CCc1ccc(OP(=O)(NC(C)C(=O)OC)OCC2C=CC(n3cc(C)c(=O)[nH]c3=O)O2)cc1 +O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)CCN1c1ccc(F)cc1 +Cc1ccc(COc2ccc(C=CC(=O)NC(CCCCCC(=O)NO)C(=O)Nc3cccc4cccnc34)cc2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(N3CCC(O)CC3)c2cn1)c1ccccc1 +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4ccc(OCc5ccccc5)cc4)o3)cc2Cl)CS1(=O)=O +Cc1cc(C=CC#N)cc(C)c1Nc1ccc(F)c(Nc2ccc(C=CC#N)cc2)n1 +COc1cc(-c2cnn(CCO)c2)ccc1Nc1ncc2ccnc(NC3CCCCC3)c2n1 +NCCCCC(NC(=O)CN(Cc1ccccc1)C(=O)CCc1ccccc1)B(O)O +CS(=O)(=O)N1CC2(CCN(C(=O)Nc3ccc(-c4ccccn4)cc3)CC2)c2ccccc21 +c1cnc(NCc2ccncc2)c(-c2nnc(Nc3ccc4c(c3)OCO4)o2)c1 +CNC(=O)c1cnc(-n2ncc3cc(C#N)c(N)nc32)cc1NC(C)C +CC(C)C(NS(=O)(=O)c1ccc(NC(=O)c2ccc([N+](=O)[O-])cc2)cc1)C(=O)O +O=C(c1ccc(O)cc1O)N(Cc1ccccc1)c1ccc(-c2nc(Cl)c3c(n2)CCSC3)cc1 +COc1cc(NC(=O)c2cccc(-n3ncc4cc(Nc5ccccc5C)ccc43)c2)cc(OC)c1OC +C=Cc1ccccc1C(Nc1ccc(C)cc1Cl)C(=O)CCc1ccncc1 +COc1ccc(S(=O)(=O)n2c(N)nc3c2c(=O)n(CC2CC2)c(=O)n3CC2CC2)cc1 +COCC[n+]1c2c(n(Cc3cnccn3)c1C)C(=O)c1ccccc1C2=O +N#Cc1ccc2[nH]cc(CN3CCN(c4ccc(Cl)cc4)CC3)c2c1 +C1CNCCNCCCN(CCCN2CCCNCCNCCCNCC2)CCNC1 +CN1Cc2c(C3=CC4CCCC(C3)N4C(=O)CC#N)[nH]c3nccc(c23)-c2cc(F)ccc21 +COC(=O)C(Oc1cccc(-c2ccc3sc(C(=N)N)cc3c2)c1)c1cccs1 +CCOc1ccc(-c2nc(CSCC(=O)NCc3ccco3)c(C)o2)cc1 +CCOc1ccc(N2CCN(c3noc(C(C)(C)NC(C)=O)n3)C(C)C2)c(C)c1 +COc1cc(C=C2C(=O)NN(c3ccc(C#N)cc3)C2=O)ccc1O +O=[N+]([O-])c1cccc2nc3ccccc3c(NCCCO)c12 +CCCc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +COC(=O)C(C)NC1=C(Cl)C(=O)C(NC(Cc2ccccc2)C(=O)OC)=C(Cl)C1=O +O=S(=O)(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(CCC2CCCCC2)CC1 +O=C(CCN1CCC(c2cnccn2)CC1)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1 +COc1ccc2c(c1OC)CN(C)c1c-2ccc2cc3c(cc12)OCO3 +[H]c1c(Cl)ccc(COc2cccc(C(=O)O)c2OCc2ccc(Cl)c([H])c2Cl)c1Cl +O=C(NCc1cc(F)c(N2CCOCC2)c(F)c1)Nc1cccc2cnccc12 +COc1cccc(COc2ccc(OC)cc2CCCNC(C)=O)c1 +CC(C)(C)C(=O)Oc1cc(C(C)(C)C)ccc1CN=C(S)NCc1ccc(NS(C)(=O)=O)cc1 +CN(C#N)N(C)C(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C +CCS(=O)(=O)NCCN(C1CCN2CCc3ccccc3C2C1)S(=O)(=O)CC +CCCCC(=O)c1c[nH]c2ccc(CCc3ccccc3)cc2c1=O +CN1CCC(Nc2cc(-c3ccc(C(F)(F)F)cc3)c(C#N)c3nc4ccccc4n23)CC1 +CCCc1ccc(S(=O)(=O)NCC2CCCN2c2nc(NCc3csc(-c4ccccc4)n3)nc(NCC(C)C)n2)cc1 +CN1CCC(c2c(O)cc(O)c3c(=O)cc(-c4ccc(F)cc4)oc23)C(O)C1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1cc(C(F)(F)F)nn1-c1ccccc1F +CC(C)(NS(=O)(=O)c1cc(F)c(F)cc1F)C(=O)NC1C2CC3CC1CC(C(N)=O)(C3)C2 +CSc1nn2cc(-c3nc4cc(C(C)(C)C)ccc4o3)nc2s1 +COc1cc(OC)c(OC)cc1CNc1cnc2nc(N)nc(N)c2c1 +CSc1ccc(-c2nc(-c3ccncc3)c(-c3ccc(F)cc3)n2C)cc1 +O=C(Nc1ccccc1)N(Cc1cc(Br)ccc1O)c1ccc(Br)cc1 +O=C(CCCCCCNC(=O)N1Cc2ccccc2C1)NCC1CCOC1 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+Cc1ccc(C(=O)Nc2ccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c(F)c2)c(=O)n1-c1ccccc1 +CN(C)c1ccc(C(=O)NCCCCCCNC(=O)CS)cc1 +O=S(=O)(Nc1nncs1)c1cc(Cl)c(Oc2ccc(Cl)cc2-c2ccnn2CCO)cc1F +CC1(C(=O)Nc2ccc(N)nc2)CCCN1c1nc(Nc2cc(C(N)=O)[nH]n2)c2cccn2n1 +Cc1ncoc1-c1nnc(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3F)C2)n1C +CC1CCC(Cn2c(N3CC(O)CC4CCCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CC(Nc1nccc(N2C(=O)OCC2(C)c2ccccc2)n1)c1ccc2ccccc2c1 +O=C(O)C=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCC1 +COC(=O)C1=C(CN2CCOCC2C(=O)O)NC(c2ncc(F)cc2F)=NC1c1ccc(F)cc1Cl +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCCC(C)(F)F +COCc1cc(-c2nc(-c3ccc4c(c3)CN(CCC(=O)O)CC4)no2)ccc1-c1ccccc1C +CNC(=O)C1OC(n2cnc3c(NCc4cccc(Cl)c4)nc(N)nc32)C(O)C1O +CC(C)CN(C(CO)CCCCNC(=O)N(Cc1ccccc1)Cc1cccnc1)S(=O)(=O)c1ccc(N)cc1 +CCOc1ccc(C(=O)Nc2ccc(N(C)S(C)(=O)=O)c(OCc3cc(C)ccc3C)c2)cc1 +Cc1noc(C)c1-c1ccc2nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc2c1 +COc1cccc2c1C1CCN(CCNC(=O)c3ccc(F)cc3)CC1C2 +NC(=O)c1cccc(-c2ccc3ncnc(Nc4cccc5[nH]ncc45)c3c2)c1 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+O=C(Cc1ccc(F)cc1)Nc1ccc2c(c1)CC(=O)N(O)C2=O +CCN(CC)S(=O)(=O)c1ccc(C(=O)NCc2nnc(SCC(=O)N3CCc4ccccc43)n2-c2ccccc2OC)cc1 +Oc1nc(-c2ccc(-c3c(COc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cn2)no1 +O=C(NCc1ccccn1)c1ccc2c(c1)Cc1c(-c3ccc(-c4ccc(O)cc4)cc3)n[nH]c1-2 +Cc1ccc(S(=O)(=O)Nc2cc(C3C([N+](=O)[O-])C(c4ccccc4Br)CCN3Cc3cccnc3)ccc2O)cc1 +CC(C)C(C(=O)O)N1CC(CN2CCC(c3ccc(F)cc3)CC2)C(c2ccccc2)C1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)c1C +CCCOC(=O)Nc1ccc(S(=O)(=O)N2CC(c3ccccc3)NC2=O)cc1CC +N#Cc1ccc(NC2CNC(C(=O)N3CCCC3C#N)C2)cc1C#N +O=C(c1cc2ccccc2o1)N1CC(=O)N(Cc2ccc(Cl)cc2)C(Cc2ccccc2)C1 +CC(=CC(O)CC(C)=CCCc1ccoc1)CCC(O)C1(C)CCC(=O)O1 +CC(C)Oc1cccc(-c2c[nH]c3ccc(-c4nnc(N)o4)nc23)c1 +COc1ccc(CC(N)c2nc3ccc(-c4cn[nH]c4)cc3c(=O)[nH]2)cc1 +COc1ccc(S(=O)(=O)C(C)(Cc2ccc(OCCN(C(C)C)C(C)C)cc2)C(=O)NO)cc1 +CCN(CCN1CCN(c2ccc(OCCOC)cc2)CC1)c1cc2nc(-c3ccco3)nn2c(N)n1 +CCN(CC)C(=O)Cn1c(-c2ccc(OC)cc2)nc2c(C)cc(C)cc21 +O=C(O)CCCCC=C(c1cccnc1)c1cccc(F)c1 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+O=C(O)c1n[nH]c2cc(Cl)c(-c3ccc4c(c3)CCO4)cc12 +CC(NC(=O)c1cccc(CN2C(=N)NC(C)(C(C)C)CC2=O)c1)c1ccccc1 +CNc1nc(-c2ccccc2Cl)c2c(n1)N(c1c(Cl)cccc1Cl)C(=O)NC2 +CCOc1ccc(Cc2ccccc2OC2CC(CO)C(O)C(O)C2O)cc1 +Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(C#N)c(Oc3ccccc3)c(C#N)c2c1 +COc1ccc(-c2ccccc2N2CCN(CCCCCC(=O)NCc3ccc(OCCN4CCOCC4)cc3)CC2)cc1 +Cc1c(CN2CCCC2)cc(-c2ccc(N)cc2)n1Nc1ccnc2cc(Cl)ccc12 +Cc1cccc(CNc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1C +CNC(=O)C1CC(O)C(n2cnc3c(NC)ncnc32)O1 +O=C(Nc1cccnc1)N1CCC(Cc2cccc(Oc3ccc(Cl)cn3)c2)CC1 +O=C1c2ccc(CN(CCO)CCO)cc2C(=O)c2nccnc21 +CC1(C)N=C(N)N=C(N)N1OCCCOc1cc(Cl)c(Cl)cc1Cl +O=C(CCCN1CCN(C(=O)c2ccccc2)CC1)NC1c2ccccc2CSc2ccccc21 +Cc1cc(CCCCCCC(Cc2cc(C)c(F)c(C)c2)C(=O)NO)ccc1F +Fc1ccc(-c2nc(CN3CCN(c4ccccc4)CC3)cn2-c2ccc(F)cc2)cc1 +O=C(NC1CC(O)CC1OC(=O)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1)c1ccc(O)cc1 +CC(C)CCNC(=O)C(C)NC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)C(C)(C)C)C(C)C +Cc1cc(C(=O)O)c2nc(-c3c(F)c(F)c(-c4ccc(NC(=O)C5CCCN5)cc4)c(F)c3F)[nH]c2c1 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+O=C(c1ccccc1)n1cc(C2=CCNCC2)c2cc(F)ccc21 +CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2Cc2cnccc2Cl)C1 +CC(C)c1ccc(S(=O)(=O)n2c(CCN3C(=O)c4ccccc4C3=O)nc3cc(Cl)c(Cl)cc32)cc1 +COc1ccc(C2SCC(=O)N2CCNc2ccnc3cc(Cl)ccc23)cc1O +Cc1ccc(-n2nc3c4cc(CCc5ccccn5)ccc4[nH]c(=O)n3c2=O)cc1 +O=C(N=C1SSC2=NCCN21)c1ccc(C(F)(F)F)cc1 +O=C1NCCN1c1ccc(S(=O)(=O)Nc2ccc3c(c2)CCC3)cc1 +Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCCc3ccccc3)C2=O)cn1 +CN(C)c1cccc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)n1 +CC1(O)c2ccc(C#Cc3cc(Cl)ccc3OCC(=O)O)cc2S(=O)(=O)C1(C)C +Oc1ncnc2nc(-c3ccc(F)cc3)c(-c3ccc(F)cc3)nc12 +CN1C2CCC1C(C(=O)OCCc1ccc(N=C=S)cc1)C(OC(=O)c1ccccc1)C2 +CC(C)C(OC(=O)N1CCN(C(=O)N2C(=O)C(Cc3cccc(CN)c3)C2C(=O)O)CC1)C(C)C +CCCCc1nc(Cl)c(C(=O)Oc2ccc3c(c2)CCC3)n1Cc1cccc2c1ccn2-c1ccccc1-c1nn[nH]n1 +Nc1ccc(I)cc1C(=O)NCC(=O)NC1CCN(Cc2ccc(Cl)cc2)C1 +COc1ccc(NC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NCC2(c3cccnc3)CCCCC2)cc1 +O=C(O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(C#Cc2ccc([N+](=O)[O-])cc2)s1 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+CC(=O)Nc1ccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)cc1 +Oc1cccc(C23CCCC(C2O)N(CCC=Cc2ccccc2)CC3)c1 +Nc1nc(NC2CCCCC2)c2c(-c3ccccc3)c(-c3ccccc3)[nH]c2n1 +COc1ccc(Cn2c(CC(C)(C)CC(=O)O)nc3ccccc32)cc1 +CC(Nc1nc(-n2cnc3ccncc32)nc2c1cc(C(=O)N1CCOCC1)n2C)c1ccccc1 +NCC1CCC(CNc2nc(NCc3ccccc3[N+](=O)[O-])ncc2[N+](=O)[O-])CC1 +O=C(O)CN1C(=O)c2c(I)c(I)c(I)c(I)c2C1=O +Cc1nc2cnccc2n1CC1CCN(C(=O)C=C(c2ccccc2)c2cccc(N)c2)CC1 +COc1cc2c(cc1OC)CN(C(=O)C(Cc1ccccc1)C(=O)c1cc(Cl)cc(Cl)c1)CC2 +O=C(NCC(NC(=O)c1c(Cl)cc2c(c1Cl)CCN(C(=O)c1cccc(Cl)c1)C2)C(=O)O)c1cccs1 +CC(C)(C)c1ccc(S(=O)(=O)Nc2cccc(S(N)(=O)=O)c2)cc1 +COc1cc(OC)cc(OC2=C(Cl)C(=O)c3c(O)ccc(O)c3C2=O)c1 +Cc1ncc([N+](=O)[O-])n1CCOS(=O)(=O)ON +CCCCCCCc1ccc(NS(=O)(=O)c2ccc3c(c2)CCN(Cc2ccc(C(C)(C)C)nc2)C3)c(F)c1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(CN)cc3)nc2n1 +COC1(C)CNCCN(c2cccc(-n3ncc4cnc(-c5cnn(CC(F)(F)F)c5)cc43)n2)C1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(COc3ccc(F)cn3)SCC2C)c1 +COc1cccc2c(Nc3ccc(NS(C)(=O)=O)cc3N(C)C)c3ccccc3nc12 +CCN(CC)Cc1cc(N(c2cc(C)nc3cc(Cl)ccc23)S(=O)(=O)c2ccc3ccccc3c2)ccc1O +CC1C(=O)NCC1C(=O)Nc1cc(-c2cccc(COC(C)C(F)(F)F)c2)n(-c2ccccc2)n1 +COc1cc2c(N)nc(N3CCN(C(=O)CC(N)c4ccccc4)CC3)nc2c(Br)c1OC +CC(CS)C(=O)N1C(SCc2ccccc2)CCC1C(=O)O +NC(Cc1nc2cccc(Cl)c2cc1CP(=O)(O)O)C(=O)O +CN1CCN(Cc2ccc(Nc3ncc(Cl)c(Nc4ccccc4C(=O)N(C)C)n3)cc2)CC1 +CN(C)CC1CC2c3ccccc3Cc3ccc(-c4ccccc4)cc3N2O1 +CCCc1cc(Nc2ccnc3cc(Cl)ccc23)cc(CNC(C)(C)C)c1O +COC(=O)c1cc(-c2c[nH]c3ccccc23)[nH]n1 +C#CCN(Cc1cnc2nc(N)nc(N)c2c1C)c1cc(OC)c(OC)c(OC)c1 +Cc1nn(Cc2ccc(-c3nc4cc(Cl)ccc4[nH]3)cc2)c(C)c1CC(=O)O +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(CC3CCN(C)CC3)C2=O)cc1 +Cc1csc(-c2cc(-c3c(C)noc3C)c3n(c2=O)CCCc2ccncc2-3)n1 +CONc1nc(C#Cc2ccc(CC#N)cc2)nc2c1ncn2C1OC(CO)C(O)C1O +COCCOc1c(C=C2SC(=O)NC2=O)cccc1C(F)(F)F +COc1cc(F)ccc1-c1nc2c(NCCCNC(=O)C3CCC3)c(Br)cnc2[nH]1 +O=c1cc(C=Cc2ccc(O)c(O)c2)oc2cccc(O)c12 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc(-c5cccnc5)n[nH]4)c3)cc2C1 +Cc1ccc(N2CCN(C(=O)C3CCS(=O)(=O)CC3)C(c3cccc(F)c3)C2)nc1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cn2ccnc2)cc1 +CC1CCC2(C(=O)N3CCNCC3)CCC3(C)C(=CCC4C5(C)Cc6cn[nH]c6C(C)(C)C5CCC43C)C2C1C +C#Cc1c(Oc2ccc(-n3cc(C(=O)NCc4ccc(F)cc4)ccc3=O)cc2F)ccnc1N +NC(=O)Nc1sc2c(c1C(N)=O)CCc1nn(C3CCCN(Cc4ccc(Cl)cc4)C3)cc1-2 +Cc1ccc2nc(N(Cc3ccc(F)c(C(F)(F)F)c3)S(=O)(=O)c3ccccc3)c(C)n2c1 +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)Nc5ccc(Cl)c(Cl)c5)cn4c3)cc2)CC1 +CC(=O)N1CCC(c2nc(-c3ccc([S+](C)[O-])cc3)c(Sc3ccc(Cl)cn3)o2)CC1 +O=C(O)c1cc(-c2ccsc2)c2ccc(OCc3c(F)cc(F)cc3F)cc2c1 +CCOC(=O)c1cccc(NC2=NC(N)=NC3(CCCCC3)N2)c1 +Cc1ccc2c(-c3ccnc(Nc4ccc5c(c4)OCCO5)n3)c(-c3ccc(F)cc3)nn2n1 +CCc1c(C#N)c(-c2ccc(-c3cccc(F)c3)cc2)c(C(=O)O)n1C +O=C(OCCC12CC3CC(CC(C3)C1)C2)c1cc(N(O)C2CCCO2)on1 +COc1ccc(C=C2CNCC(=Cc3ccc(OC)c(O)c3)C2=O)cc1O +COCC(=O)NC(C)CNc1nc(-c2ccc(C(C)(C)O)nc2)cc2ncn(C)c(=O)c12 +CC1C(c2ccc(F)cc2)OC(=O)N1c1cc(F)cc(C#N)c1 +COCOc1cc(OC)c(OC)cc1-c1c(C(=O)OC)[nH]c(C(=O)OC)c1-c1ccc(OC)c(OC)c1 +CC(C)(C)c1cc(COCC(c2ccccc2)N2CCNCC2)cc(C(C)(C)C)c1 +CC(c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2)OC1=O +Cc1cc(F)ccc1Nc1nc(N(C)c2ccccc2)c2cccc(OCCO)c2n1 +COc1ccc2ccc(=O)oc2c1C1=NN(S(=O)(=O)c2ccc(Cl)cc2)C(c2ccc(SC)cc2)C1 +CCC#CCC(C)C(O)C#CC1C(O)CC(F)C1CC(=O)CCCCC(=O)O +COc1cc(Nc2nc3n(n2)CCC(=O)N3Cc2ccccc2C)ccc1-c1cnnc(C)c1 +O=c1[nH]c(CN2CCCCC2)nc2cc(-c3cn(Cc4ccccc4)c4ccccc34)sc12 +Cc1ccc(C(O)C2CCCC3=Cc4c(cnn4-c4ccc(F)cc4)CC32C)cc1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCOC1CCN(Cc3ccccc3)CC1)C2 +CCOC(=O)c1sc(-c2ccncc2)nc1-c1ccccc1Cl +Cc1ccc(-c2ccc(-c3cc(=O)cc(N4CCOCC4)s3)cc2)c2ccccc12 +N#CCNC(=O)C(Cc1ccccc1)NC(=O)c1ccc(CN=[N+]=[N-])cc1 +CN(C)Cc1cc(C(N)=O)ccc1Oc1ccc(OC(F)(F)F)cc1 +CN1CC(N2CCN(c3cc(C(F)F)cc(Nc4nc(NC5CC5)c5ncc(C#N)n5n4)c3Cl)CC2)C1 +CC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 +CC(C)C(=CC(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)N)c1 +O=C(Oc1ccc(S(=O)(=O)c2ccc(OC(=O)C(Cl)=C(Cl)Cl)cc2)cc1)C(Cl)=C(Cl)Cl +OCC1OC(c2ccc(Cl)c(Cc3ccc(O)cc3)c2)C(O)C(O)C1O +OCC1OC(c2cccc(Cc3ccc4cccc-4cc3)c2)C(O)C(O)C1O 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+CC(=O)Nc1ccc2[nH]cc(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 +O=C(CCCCN1CCC(c2ccccc2)CC1)n1c2ccccc2c2ccccc21 +Cc1cccc(OCC(=O)NCC(=O)NN=Cc2cc(Br)cc(Br)c2O)c1 +COC(=O)c1c(-c2c(F)cccc2Cl)noc1C=CNc1ccc(OC)cc1 +CCCN1CCc2cccc3c2C1Cc1cccc(OCCCn2cc(CN4CCN(c5ccccc5OC)CC4)nn2)c1-3 +CC(=Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NC(CO)C(=O)O +COc1ccccc1N1CCN(CCC2Cc3ccccc3C2=O)CC1 +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1nc(Cl)cs1)COCC3 +CN1CCN(CCCNCc2cn(-c3ccc(C(F)(F)F)cc3)nc2-c2ccc(Cl)cc2)CC1 +NC(=O)n1cc(NC(=O)N2C(C(=O)NCCOC(F)(F)F)CC3CC32)c2ccccc21 +COc1cc(Nc2ncc(C(=O)NO)cn2)cc(C(F)(F)F)c1 +COC(=O)c1cc(C(O)CN2CCC(n3c(O)nc4ccccc43)CC2)ccc1O +Oc1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)c1c-2ccc2cc(O)ccc12 +CC(C)(C)c1nc(N2CCN(CCCCNC(=O)c3cn4cccnc4n3)CC2)cc(C(F)(F)F)n1 +CCC(CC)(NC(=O)c1cc(OCC2(C)COC2)c(C2CC2)cn1)C(=O)NCCCF +O=C1NN=C(c2cnns2)C1=Cc1cc2c([nH]1)CCCC2 +CCNC(=O)Nc1cc(Nc2ccccc2)c(C(=O)Nc2cccc(Cl)c2)cn1 +COc1ccc(CNCc2cc(-c3ccnc4cc(Cl)ccc34)ccc2O)c(OC)c1 +COC(=O)N1CCC(Nc2ncccc2-c2cnc3[nH]ccc3n2)CC1 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+CCCC(CCC)(c1ccc(O)c(CC)c1)c1ccc(O)c(CC)c1 +O=C(Nc1[nH]nc(C(=O)NC2CCCCNC2=O)c1Br)c1ccccc1Cl +CN1CCN(CCCN2CC3C(c4ccccc4)CC(N(C)C)(CC3c3ccccc3)C2)CC1 +COc1cnc(C(=O)Nc2cc(F)c(F)c(C3(C)CC(C(F)(F)F)OC(N)=N3)c2)c(C)c1 +CN(Cc1ccccc1)Cc1ccc(-c2cc3cc([N+](=O)[O-])ccc3oc2=O)cc1 +O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2ccc(Br)cn2)C2C=CC1C21CC1 +CCOC(=O)c1ccc(NC(=O)Cn2nnc(-c3ccc(C)cc3)n2)cc1 +O=C(Nc1ncc(F)s1)C(CC1CCOCC1)n1ncc2c(S(=O)(=O)C3CC3)cc(F)cc21 +CC(=O)Oc1ccccc1C(=O)OCOC(=O)CCCCC(CO[N+](=O)[O-])O[N+](=O)[O-] +O=C(NCC(c1ccc(C(F)(F)F)nc1)N1CCOCC1)c1c(F)cccc1Cl +O=C(NCC(C(=O)NO)N1CCN(Cc2ccccc2)CC1)c1ccc(OCc2c(C(F)(F)F)nn3ccccc23)cc1 +COc1ccc(NC(=O)c2ccc(Cl)c(Nc3ncnc4cnc(N5CCCN(C)CC5)nc34)c2)cc1C(F)(F)F +O=C(Oc1cn(-c2ccccc2)c(CSc2nc3ccccc3s2)cc1=O)c1ccccc1 +Cc1nnc(-c2c(-c3nnc(C4(C(F)(F)F)CC4)o3)nn(-c3ccc(Cl)cc3Cl)c2-c2ccc(Br)cc2)o1 +OC1CCCCCCCNc2ncc3c(C4CCOCC4)cn(c3n2)CCCC1 +CCOc1ccc2c(c1)c(C#N)cn2-c1ccc(C(=O)O)c(O)c1 +COc1cncc(-c2cc3c(-c4cccc(N5CCNCC5)n4)n[nH]c3cn2)c1 +CCCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)C2)cc1 +CC(C)N1CCN(C(=O)c2ccc3c(CN4CCCCC4)cn(S(C)(=O)=O)c3c2)CC1 +Cc1nc(-c2ccc(S(=O)(=O)Nc3cccc(-c4nnn[nH]4)c3)s2)cs1 +N=C(N)NCCCC(NC(=O)c1ccc(-c2ccccc2)cc1)B(O)O +O=C(C=Cc1cccc(S(=O)(=O)c2ccc3cccc(F)c3n2)c1)NO +CS(=O)(=O)c1ccc(Nc2ncnc(N3CCC(c4nc(C5CC5)no4)CC3)c2[N+](=O)[O-])cc1 +O=C(O)CCCOc1cccc(C=Cc2ccc3cc(Cl)ccc3n2)c1 +COCCOc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccco2)cc1 +CN1CCN(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c3ncccc23)CC1 +CCOC(=O)Oc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(C)=O)CC2 +Nc1nc(N)c2c(-c3cccc(Cl)c3)c(-c3ccc(F)cc3)[nH]c2n1 +O=C(NCCc1ccccc1Cl)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +OC1C(F)C2N=C(N3CCC3)SC2OC1C(O)C(F)(F)F +CS(=O)(=O)c1ccc(-c2sc3nc(C(F)(F)F)nn3c2-c2cccc(F)c2)cc1 +Cc1ccc2cccc(C)c2c1-n1c(C)nnc1SCC(=O)Nc1ccccc1Br +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2ccc(Cl)cc2)c(C)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=NOCc1ncc[nH]1 +COc1ccccc1N1CCN(CCN2C(=O)CC(c3ccc(Cl)cc3)CC2=O)CC1 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+O=c1oc2c3c(ccc2c(O)c1Cc1cccc2ccccc12)CCCC3 +COc1ccc(C(=O)NCCO)cc1C=Cc1ccc(Cl)cc1 +CC1OC23CC(c4ccc(C(F)(F)F)cc4)OC(=O)C2=CC1(C)OO3 +O=Cc1cc(-c2ccc(C(=O)O)cc2)cc(F)c1O +Cc1cnc2c(-c3ccc(F)cc3)c(-c3ccc(S(C)(=O)=O)cc3)nn2c1C +CCCOc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cc1Cl +COc1ccc2ccn(C3CCN(c4ccc(-c5cnn(C)c5)nn4)CC3)c2c1 +O=C1c2ccc(-c3ccc(F)cc3)cc2CCN1CCN1CCCCC1 +Nc1nn2cccnc2c1C(=O)Nc1cn(CC(=O)N2CC3CN(CC4CC4)CC3C2)nc1-c1cc(Cl)ccc1OC(F)F +CCn1cc(C(O)C2CCCN(c3nnnc4cc(N5CCOCC5)ccc34)C2)cn1 +O=CC(CC1CCCNC1=O)NC(=O)C(Cc1ccccc1)NC(=O)CCc1ccccc1 +COc1ccccc1N1CCN(CCCOc2c(C)cccc2C)CC1 +O=C(Nc1ccc(Cl)cc1)Nc1cccnc1Oc1cccc(C(F)(F)F)c1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1ccccc1F +CC(C)NCc1ccc(-c2ccccc2-c2ccc3c4n[nH]cc4c(=O)n(CC(F)(F)F)c3c2)o1 +O=c1n(Cc2nc3cc(Cl)ccn3c2CCCCO)c2cnccc2n1C1CC1 +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccsc1 +CC#CCn1c(N2CCCC(N)C2)nc2ccn(Cc3ccc4ccc(Cl)cc4n3)c2c1=O +CCOC1CCN(c2ncnc(CC)c2C#Cc2ccc(C)nc2)CC1 +CC(C)C1NC(=O)C(NC(=O)C(O)C(Cc2ccccc2)NC(=O)OC(C)(C)C)Cc2ccc(cc2)OCCCNC1=O +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)NC(CC(C)C)C2=NOC(CCC(=O)O)C2)cc1 +CCNC1CC=C(c2c[nH]c3ccc(NC(=N)c4cccs4)cc23)CC1 +CC1=CSC(OCc2ccccc2)(c2ccc(Cl)cc2)c2noc(=O)n21 +OCC1CCCN(CCCC2CCCc3ccc(OCc4noc(-c5ccccc5F)n4)cc32)C1 +NC(=O)c1cc(-c2cnc(Nc3ccc(N4CCOCC4)cc3)c3nccn23)cs1 +Fc1ccc(Nc2ncnc3nc(Nc4ccc(CN5CCCCC5)cc4)sc23)cc1Cl +COc1cc2cc(C(=O)CC(OC)C3CC[N+](C)(Cc4ccccc4)CC3)sc2cc1OC +CCCN(CCC)CCc1ccc(OC)c(OCc2ccccc2)c1 +O=C(O)C1=C(C(=O)Oc2ccc(F)c(F)c2F)CCC1 +CN(C(=O)C=Cc1ccoc1)C1CCC2(O)C3Cc4cccc5c4C2(CCN3CC2CC2)C1O5 +CC1CN(Cc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)CC(C)O1 +COc1cccc(COC(=O)C2=C(C)NC(=O)NC2c2ccco2)c1 +Cc1cc(C)c(-c2csc(NC(=O)Cc3ccncc3)n2)c(C)c1 +CC(=O)N1CCN(Cc2ccc(Oc3ccc(Cl)cc3O)s2)CC1 +Cc1cccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)c1 +CCC1c2nnc(C(F)(F)F)n2CCN1C(=O)CC(N)Cc1cc(F)c(F)cc1F +CCc1c(N2CCOCC2=O)cccc1S(=O)(=O)NC(Cc1cc(-c2ccc(Cl)s2)on1)C(=O)N1CCC(O)CC1 +CN(C)CCON=C1C(=O)c2c(nc3ccccn23)-c2ccncc21 +CCCNc1ncc(-c2ccc(Oc3ncc(NC(=O)Nc4cc(C(F)(F)F)ccc4S(=O)(=O)N(C)C)cn3)cc2)s1 +CCN(CC)CCN(CCNCCc1ccc(O)c2[nH]c(=O)sc12)C(=O)CCOCCc1cccc(F)c1 +CCCc1nc(COC)n2nc(O)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCCc1nc2[nH]ncc2c2nc(-c3ccc(C)cc3)nn12 +Cn1cc(C2=C(c3c4n(c5ccccc35)CCC(N)C4)C(=O)NC2=O)c2ccccc21 +CCCN1CCc2cccc3c2C1Cc1ccc2c(C)c(C)oc2c1-3 +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(-c3nccs3)cc12)C(=O)O +CN(C(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C)C1COC1 +CN(C(=O)CC(N)C1CCN(C(=N)N)CC1)C1CNC(NC(N)=O)=NC1=O +Cn1cnc(-c2ccnc(Nc3cc(Cl)c4[nH]c(C(=O)N5CCN(c6nccn6C)CC5)cc4c3)n2)c1 +Clc1ccc(C(OC2CC3CCC(C2)N3)c2ccccc2)cc1 +NC(=O)c1c(Oc2ccc(F)c(NS(N)(=O)=O)c2F)cc(F)c(F)c1Nc1ccc(I)cc1F +O=C(Nc1cc(C(=O)N2CC3CC2CN3)nn1-c1ccccc1)c1cc(-c2ncccc2F)ccc1Cl +CC(C)N1CCC(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CC1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4cccc([N+](=O)[O-])c4)cc3F)ccnc2cc1OCCCN1CCCCC1 +OCC(O)CN1C(CCc2cccc(F)c2)CCCC1CCc1cccc(F)c1 +CCNC(=O)OCc1c(COC(=O)NCC)c2n(c1CC)Cc1c(c3ccccc3n1C)C2 +COCCn1ccn2cc(C(=O)NCc3ccc(F)cc3)c(=O)c(O)c2c1=O +COc1cc(C#Cc2cn(C3CN(C(=O)C=CCN(C)C)C3)c3ncnc(N)c23)cc(OC)c1 +O=C(NC1CC1)c1ccc(Cl)c(Nc2nncc3c2cnn3-c2cc(F)ccc2F)c1 +CN1CCN=C1c1ccc(C(=O)N2CCN(S(=O)(=O)c3cc4cc(Cl)ccc4[nH]3)CC2CC(=O)O)cc1 +COc1cc2ncc(C#N)c(Nc3ccc(Br)cc3Cl)c2cc1OC +COc1cc2c(Cc3cnc4ccccc4c3)cnc(CC(C)C)c2cc1OC +CN(C)C1CCC(Nc2ncnc3ccc(C4CC4)cc23)CC1 +O=C(c1ccc(Cl)cc1)N1CCCC(c2nc(-c3ccccc3)no2)C1 +CC1(O)C2OC3(O)OC1C1C(O)NC(=N)NC1(C2O)C3O +Cc1ccc2c(c1)c(S(=O)(=O)c1c(Cl)cccc1Cl)c(C)n2CC(=O)O +CNC(C)C(=O)NC(C(=O)NC1CCCN(CCc2ccccn2)C1)C(C)(C)C +NC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1O +CCN(CC)CCn1c(=N)n(CC(O)c2ccc(Cl)c(Cl)c2)c2ccccc21 +CC(C)N(C)CC=Cc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +COc1cc(OC)cc(N(c2ccc3ncc(-c4cnn(C)c4)nc3c2)C(C)CN)c1 +CCCCOn1c(Sc2cc(C)cc(C)c2)c(C(C)C)c(=O)[nH]c1=O +COc1ncc(-n2ncc3c(NCC(C)NS(=O)(=O)c4c(C)nn(C5CCCC5)c4C)cccc32)cn1 +CC(C)(C)c1cncc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC3)n2)n1 +CC(Nc1cc(-c2[nH]c([S+](C)[O-])nc2-c2ccc(F)cc2)ccn1)c1ccccc1 +CN1CCN(C(=O)n2oc(=O)c(-c3ccc(F)cc3)c2-c2ccncc2)CC1 +CC1(C)CN(C2=CCCC2=O)c2cc(C(F)(F)F)ccc2S1 +Cc1c(Cc2ccc(F)c(C(=O)N3CCN(C(=O)C4CCNC4)CC3)c2)n[nH]c(=O)c1C +CCCCN1CC(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(OCc3ccccc3)CN2)CC1=O +CN(C)C(=O)Cn1c(=O)c(C(=O)NCc2ccc(F)cc2)c(O)c2ncc(Cc3ccc(F)cc3)cc21 +N#Cc1ccccc1N1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +c1cc(-c2n[nH]c3cnc(-c4cncs4)cc23)nc(N2CCNCC2)c1 +Cc1cc(NC(=O)C(=O)c2cn(Cc3cc(C(C)C)no3)c3ccccc23)sn1 +CC(F)CS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(c2ccccn2)CC1 +CN1CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O +CN(C)c1ccc(C(=O)NCCCCCCCC(=O)NO)cc1 +Cn1cncc1C(O)(c1ccc2nc(Cl)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1)c1cncn1C +C=C1C(O)CC(=CC=C2CCCC3(C)C2CCC3C(C)Cn2ccnc2)CC1O +CC(CNCc1ccccc1)C(=O)NC(CCc1ccc2c(c1)OCCCO2)C(C)C +CCCn1c(=O)c2nc(-c3cnn(Cc4cc(-c5cccc(OC)c5)on4)c3)[nH]c2n(CCC)c1=O +CC1=NC(C)=C(C(=O)O)C(c2ccccc2[N+](=O)[O-])C1=C(O)OCC=Cc1ccccc1 +CC(=O)NC(C)Cc1ccc(C#Cc2cnc3ccccc3c2)cc1 +O=C(CSc1nc2ccc(Nc3nc(N4CCCC4)nc(N4CCCC4)n3)cc2s1)NCc1ccco1 +Cc1ccc2nc(NC(=O)Nc3ccccc3N3CC4(CCN(CC(C)(C)C)CC4)c4c(Cl)ccc(O)c43)sc2c1 +CCCN(c1nccc(-c2c(OC)cc(OC)cc2OC)n1)C1(c2cccs2)CC1 +NCCCc1cc2cc[nH]c(=O)c2c2cc(-c3cn[nH]c3)ccc12 +N#Cc1ccc2c(c1)CCN(S(=O)(=O)c1cccc(C(=O)O)c1)C2 +CCCC(CCC)n1cnc2c1C(=O)N(C)CN2c1ccc(Cl)cc1Cl +COc1ccc(N2C(=O)OC(=Cc3ccc(O)c(Br)c3)C2=O)cc1 +Cn1c(CN2CCC(c3ccc(OC(F)(F)F)cc3F)CC2)nc2ncccc21 +COc1ccc(S(=O)(=O)N(Cc2ccc(C(C)C)cc2)C(C)C(=O)O)cc1 +CC1(C(=O)Nc2cnccn2)CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(C)O)oc12 +N#CCNCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(NC1CCC(CNc2cccnc2)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1cc(=O)oc2c1ccc1oc(C(=O)c3ccccn3)c(-c3ccccc3)c12 +Cc1sc(-c2noc(N)c2S(N)(=O)=O)cc1S(N)(=O)=O +CCCCCc1cc(O)c(CC=C(C)CCC=C(C)CCC=C(C)C)c(O)c1 +CS(=O)(=O)c1cc(Cl)ccc1CNC(=O)c1ccc(OCCC(F)(F)F)nc1 +CCCC(c1ccc(C(=O)NCCC(=O)O)cc1)C(c1ccc(Cl)cc1)c1c(C)sc2ccccc12 +Cn1nccc1-c1cc(NC(=O)c2ccc(F)c(F)c2)ccc1OCCN1CCOCC1 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+CN1C(=O)CCc2ccc(NC(=O)NC3CC(C)(C)Oc4c3ccc(Cl)c4F)cc21 +O=C(O)c1sc(-c2ccccc2)cc1-c1conc1-c1ccc(Cl)cc1 +CC(C)(O)c1coc(Cn2ncc(NC(=O)c3ncoc3-c3ccc(F)cc3)n2)n1 +Cc1nnc2c(NC3CCN(C)CC3)cc(N(C)Cc3ccccc3)nn12 +CCCn1c(=O)c2nc(-c3ccc(S(=O)(=O)NCCN(C)C)cc3)[nH]c2n(CCC)c1=O +CN(C)c1ccc(-c2cc(-c3ccc(N)cc3)[se+]c(-c3ccc(N4CCOCC4)cc3)c2)cc1 +O=C(CCCCCCNC(=O)c1ccc(C(O)(c2cccc(F)c2)c2cccc(F)c2)cc1)NO +Oc1ncnc2c(C3OC(CI)C(O)C3O)c[nH]c12 +COc1cc(C2C(C#N)=C(N)Oc3cc(N(C)C)ccc32)cc(OC)c1OC +Cc1ccc(N2CCN(C(=O)C3C(c4ccc(Cl)cc4)CCN3C(=O)C(C)(C)C)CC2)c(C(N)C(C)C)c1 +COC(O)=C1C(C)=NC(C)=C(C(=O)OCCCN2C(=O)c3ccccc3S2(=O)=O)C1c1cccc(Cl)c1Cl +CCCc1c(OCCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1Oc1ccccc1C(=O)O +CCCOc1cc(CN)cc2[nH]c(=O)c3c(c12)NCCC3 +O=C(Nc1ccc(C(=O)N2CC3COCC3C2)cc1)N1Cc2ccccc2C1 +CC1CCNC(=O)c2cc3ccc(C(=O)Nc4cnn(C)c4)cc3n21 +O=C(O)CCCC(O)C=CC=CC=CC(O)CC=CCCCCC(F)(F)F +CN(C)c1ccc(F)c(CCNC(=O)Nc2ccc(Br)cn2)c1F +CCc1nn(C2CCCC2)c2c1CCn1c(-c3ccccc3C)nnc1-2 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+O=C(O)C=Cc1ccc(NC(=O)CNC(=O)c2ccc3c(c2)nc(-c2ccoc2)n3C2CCCCC2)cc1 +CC(CNC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(N)=O +CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)NC(C)C(=O)O)n1 +CC(C)NC(=N)c1ccc2cc(-c3cccc(OCCCOc4ccccc4)c3)oc2c1 +CCP(=O)(Cc1cccc(C(=O)Nc2cc(-c3cccs3)ccc2N)c1)OC +COc1ccc(OC)c(-c2nnc3n2N=C(c2ccc(OC)c(OCC4CC4)c2)CS3)c1 +O=C(Nc1cccc(CN2CCC(C(=O)NCc3ccccc3Cl)CC2)c1)c1ccc(Cl)cc1 +Cc1nc(-c2ccccc2F)c2c(N3CCc4ccc(C5CC5)nc4C3)ncnn12 +Fc1ccc(OCC2CN(CCN3CCc4ccccc43)CCO2)cc1 +CC(C)(C)c1cc(Nc2nc(N3CCCCCC3)nc3c2CCC3)n[nH]1 +CC1CCCCC1N(C(=O)c1cc(C2CC2)on1)C1CCCCC1C +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(CO)c1ccccc1Cl +COCc1nc2c(C)ccnc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1ccc(C)c(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 +N#Cc1cccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)c1 +CC(c1ccc(-c2ccccc2)cc1)C(N)C(=O)N1CCC(F)C1 +O=C(CCCCC#Cc1ccccc1[N+](=O)[O-])c1ncc(-c2ccccn2)o1 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3c(COc4ccccc4)cccc23)C1(C)C +CC(NC(=O)c1cccc(C(F)(F)F)c1Cl)C(=O)C(N)=O +Cc1ccc(OCc2nc(-c3cccs3)no2)c([N+](=O)[O-])c1 +CC1CCCC(NC(=O)C(S)Cc2ccccc2)C(=O)N1CC(=O)O +FC(F)(F)Oc1ccccc1-c1cc(C(F)(F)F)c2[nH]c(C3=NOC4(CCCCC4)C3)nc2c1 +COc1cc(-c2nnc3n2CCCN3Cc2ccc(F)cc2)ccc1-n1cnc(C)c1 +COc1ccccc1C(O)c1cc(Cl)cc(OC)c1N(CC(C)(C)C)C(=O)CCC(=O)N1CCC(C(=O)O)CC1 +O=C(CCCN1CCC2c3cccc4c3N(CCO4)C2CC1)c1ccc(F)cc1 +COc1ccc2cc(-c3cccc(CI)c3)cc(CCNC(C)=O)c2c1 +CN1C(=N)NC(C)(c2sc(-c3ccnc(-c4ccccc4)c3)cc2F)CS1(=O)=O +COc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C(C#Cc3ccccc3)OCc3ccccc3)cc2)cc1 +COC(=O)CC1N=C(c2ccc(-c3cccc(C#N)c3)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(C)CCCc3ccccc31)CC2 +CC(C)Oc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(F)c(F)c2)cc1F +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(C2CCCCN2C)n1 +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2cccc(F)c2)c2ccc(Cl)c(Cl)c2)CC1 +CN(CCC#N)C(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)c1 +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc(C(=O)c3cccc(F)c3)c2)[nH]c1=O +CNc1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 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+O=C1Nc2cc(F)c(F)c(F)c2C(C#CC2CC2)(C(F)(F)F)O1 +COc1ccc(C(O)(c2cccnc2)c2ccc3nc(OC)c(Cc4ccc(-n5cccn5)cc4)c(Cl)c3c2)cc1OC +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CCC2(CC2)C1 +Cc1ccc(S(=O)(=O)NCC(O)CN2CCCC3(CCN(c4ncnc(N)c4C4CC4)C3)C2)c(C)c1 +Cc1ccccc1Nc1nc2ccc(N(C)C(=O)C=CCN(C)C)cc2n2cncc12 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC2CCN(C(=O)OCCCN(C)C)CC2)c2ccccc12 +Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccc(F)cc3)cc12 +CCN(CC)CCOc1ccc(Nc2nccc(-c3[nH]c(-c4c(Cl)cc(CO)cc4Cl)nc3-c3cccc(Cl)c3)n2)cc1 +CN1C(=O)Cc2ccc(-c3cc(F)c(CC(C#N)NC(=O)C4NC5CCC4C5)cc3F)cc21 +CCc1ccc(COc2ccc(N(CCN)C(=O)c3ccc(Cl)cc3Cl)cc2)cc1 +CCN(C(=O)Nc1ccc(C)cc1)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 +CN(C)CCCc1cccc2nc(CN(C)C3CCCc4cccnc43)[nH]c12 +O=C(NCCCCNc1ccnc2cc(Cl)ccc12)NC1C(=O)N(C2CCCCC2)C1C=Cc1ccccc1 +O=C(CCCCCCc1ccccc1)c1nc(-c2ccco2)no1 +COc1cc(C(=O)NC(c2ccc3c(c2)OCO3)c2cc(Cl)c3cccnc3c2O)cc(OC)c1OC +CC1(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)CC(c2cccc(Cl)c2)=NO1 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+O=C1Nc2ccccc2C2=NC(CN3CCN(c4ccccc4)CC3)CN12 +O=C(NCC(O)c1ccccc1)c1ccc(N2CCC3(C=Cc4ccccc4O3)CC2)nn1 +CN(C)CCOc1ccc(N2CCN(S(=O)(=O)c3ccc(Cl)cc3)CC2)cc1 +Nc1ncnc2c1c(-c1cc(O)cc(F)c1)nn2Cc1cc2cccc(Cl)c2c(=O)n1C1CC1 +COc1ccc(N=C2SCC3(CCCCC3)CN2C(=S)SC)cc1 +NCC1CC(c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)C1 +CN1CCC(c2cn(-c3ccncc3)c3ccc(-c4ccncc4)cc23)CC1 +OC1COC(n2cnc3c(NCc4cccc(Br)c4)ncnc32)C1O +CCCN(CC(C(=O)NO)C(CC1CCCC1)C(=O)N1CCCCC1)S(C)(=O)=O +COc1ccc(C(C)N2CCN(c3cc(Oc4cccc5sc(NC(C)=O)nc45)ncn3)CC2)cc1 +COc1ccc(Nc2ncc(N3CCC(O)C3)cc2-c2nc(C)nc3[nH]cnc23)cn1 +COCCCc1cc(C)c(C)c(CN(C(=O)C2CNCCC2c2ccn(C)c(=O)c2)C2CC2)c1 +Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C(=O)N5CCNCC5)CC4)ccc3OC(F)(F)F)ncc1CC2 +COc1cc2c(cc1OCC1CCN(C)C1)N=C(N)C21CCC1 +O=C(O)Cc1nn(Cc2nc3cc(F)ccc3s2)c2ccc(Cl)cc12 +CCN(C)CC1CCC(Nc2c(C(C)=O)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)CC1 +COc1ccc(CN(C)C(=O)c2ccc(N(Cc3cccnc3)C(=O)c3cc(Cl)c(O)cc3O)cc2)cc1 +N=C(N)c1ccc(CNC(=O)C(CO)NC(=O)C(CO)NS(=O)(=O)Cc2ccccc2)cc1 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+CCCN(CCCN=[N+]=[N-])C1CCc2c(O)cccc2C1 +CON=C(N)c1ccc(-c2cn3cc(-c4ccc(C(N)=NOC)cc4)c(C)cc3n2)cc1 +CCCCc1nn(CCCCC(=O)OC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1occc1C(=O)Nc1ccc(C(=O)N2CCC(F)(F)C(=CC(=O)N3CCC(N(C)C)CC3)c3ccccc32)cc1 +Cc1nc(NC2CCC(C)CC2)nc(-n2ccnc2C)c1[N+](=O)[O-] +CC1CC1C(=O)NC1CCC(Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(C(=O)N(C)C)CN1 +O=C(NC1CCCC1NC(=O)c1ccc(Cl)c(Cl)c1)c1ccc(-n2ccccc2=O)cc1 +CCn1nc(CCc2nc3c(C)ncc(C)n3n2)nc1N1CCCC1 +Cc1cccc2c1C(=O)N(c1ccc(NC(=O)c3nccn3C)cc1Cl)C2=O +CCCCc1nc(C)n2nc(O)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(C)c1nc(-c2cccc(NS(=O)(=O)c3cccc(F)c3)c2)c(-c2ccnc(NC3CC3)n2)s1 +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(NC(=O)Nc3cc(F)cc(F)c3)CCc3ccccc32)c1 +O=C1CN(C(=O)c2ccccc2)C2(CCN(Cc3ccccc3)CC2)C(=O)N1C1CCCCC1 +Cn1nccc1-c1nnc2n1CCN(C(=O)c1cccc(C(F)(F)F)c1Cl)C2 +COc1cc(-c2cccc(F)c2)c(Cl)cc1-c1nccc2cc(S(=O)(=O)Nc3ncccn3)ccc12 +Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(Br)ccc4OC(F)(F)F)cc3)cc2n1 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+COc1ccc2c(c1)C(=O)c1ccc(Nc3cc(F)cc(F)c3F)cc1CC2 +CCN(CCc1ccc(Cl)cc1)C(=O)C1CCN(CCCN(C(=O)C2CCN(C(C)=O)CC2)c2cccc(Cl)c2)CC1 +Cc1ccc(CN2CCOCC2)cc1NC(=O)c1ccc(Nc2ncc(C)c(-c3ccccc3)n2)cc1 +Cn1cc2c(nc(N)n3nc(-c4ccc([N+](=O)[O-])cc4)nc23)n1 +Cc1ccccc1Cc1cc2c(N(C)c3cccc(Br)c3)nc(N)nc2[nH]1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCCCC2)cc1 +CCCc1nc2c(C)cc(C(=O)NCCc3ccccc3F)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(NC1(c2ccccc2)CCC1)C1CCCC1c1cc(-c2ccc(C(F)(F)F)cc2O)on1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(COC(=O)C(C)N)cccc4n3)c(C)c12 +N#CCc1cc(O)cc2cc(-c3ccc(O)cc3)oc12 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(-c3ccc4c(c3)OCO4)nc2)cc1 +Cn1nccc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2ccc(F)cn2)cc1Cl +O=c1ccc2ncc(F)cc2n1CCN1CCC(NC(=S)Nc2ccc([N+](=O)[O-])cc2)CC1 +CN1CCN(Cc2ccc(-c3nc4c(C(N)=O)cccc4[nH]3)cc2)CC1 +COc1ccc(CNC(=O)c2ccc(NC(C)=O)cc2)c(C(F)(F)F)c1 +COc1ccc(C(=O)NCc2cccc(C(=O)Nc3ccc(CN(C)C)cc3)c2)cc1Cl +Cc1nc(-c2cc(Cl)ccc2Cl)n2c1nnc1ccc(Cl)cc12 +Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCCCNc1c3c(nc4cc(Cl)ccc14)CCCC3)O2 +O=C(CCCCCCNC(=O)c1c[nH]c2ccccc12)NO +CC(C)(C)c1ccc(C(=O)NNc2c(Cl)cccc2Cl)cc1 +CN1CCC(N(C)C(=O)N2CCC(N(C)C(=O)c3ccc(-c4cccc(Cl)c4)s3)C2)C1 +CC(C)n1c(Nc2ccccc2)nc2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3)nc21 +COc1cc(CC(=O)Nc2nc3ccc(OC(F)(F)F)cc3s2)cc(OC)c1OC +OCc1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc12 +CC1=C(Sc2cccc(F)c2)C(COCCO)C(=O)NC1=O +O=C(NCC1Cc2ccccc2CN1C(=S)NCC1CCCN1Cc1ccccn1)Nc1ccccc1 +COc1ccc(-n2nc(CC(C(=O)O)c3ccc(Cl)cc3)cc2-c2ccc(Cl)cc2)cc1 +CC1CCC(COc2ccc(F)cn2)CN1C(=O)c1cc(F)ccc1-n1nccn1 +CC(Nc1nccc(N2C(=O)OCC2(C)c2ccc(F)cc2)n1)c1ccc(Oc2ccccc2)cc1 +COc1cc(Cl)ccc1-c1ncnc2cc(S(=O)(=O)Nc3ncns3)ccc12 +CCCCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2 +COc1ccccc1N1CCN(CCCCCCn2ncc(N3CCN(CC4COc5ccccc5O4)CC3)c(Cl)c2=O)CC1 +CC(C)Oc1ccc(Nc2cc(=O)n(CCCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +COC(=O)CC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)C2C(N3CCCC3)CCCC21 +CC1(CS(=O)(=O)N2CCC(Oc3ccc(OCc4cccc(C#N)c4)cc3)CC2)NC(=O)NC1=O +CN(c1ncccc1CNc1c(C(F)(F)F)cnc2[nH]c(-c3ccc(F)cc3)cc12)S(C)(=O)=O +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CNC1)C2c1ccc(Sc2nc3cccc(Cl)c3[nH]2)o1 +CC(C)CN(NC(=O)c1ccc(CN2CCN(C)CC2)o1)c1nc(C#N)ncc1Br +CC(C)Cc1nc2ccc(OCC(N)=O)cc2c(-c2ccc(F)cc2)c1CN +c1cc(-c2c[nH]c3ccc(-c4nncs4)cc23)nc(N2CCOCC2)c1 +O=C(CCN1CCC(c2ncccn2)CC1)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1 +CC(C)c1cccc(C(C)C)c1NS(=O)(=O)NCC1(c2ccccc2)CCCC1 +CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CCC(O)C3)c(Cc3ccnc4ccccc34)sc21 +CC(=O)Nc1c2ccccc2c2c3c(cccc13)C(=O)C(CCN(C)C)C2=O +CC1=C(c2ncnn2C2CCC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 +Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cccc(F)c2)C(N2CCC2)CC3)c1 +OC1(c2ccccc2Cl)CCN(Cc2c[nH]c3ccccc23)CC1 +Cc1c(Cn2c3ccccc3n3c(=O)cc(N4CCOCC4)nc23)cccc1C(F)(F)F +Cc1cc(C)c(Nc2nc(N)nc(NC3CCN(Cc4ccncc4)CC3)n2)c(C)c1 +CCC(CO)Nc1nc(Nc2cc(Cl)cc(C(=O)O)c2)c2ncn(C(C)C)c2n1 +CCc1c(C(=O)C(N)=O)c2c(OC)cc3ccccc3c2n1Cc1ccccc1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(NCC3CCO3)c2n1 +CCC(=O)C(c1ccc(O)cc1)C1CCN(CCc2ccccc2)CC1 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+CON=C(N)c1ccc(-c2cncc(-c3ccc(C(N)=NOC)nc3)n2)cc1 +CCOc1c(C(=O)Nc2nn[nH]n2)oc2c3ccccc3n(-c3ccccc3)c12 +CC1CN(C(=O)COc2ccc(Cl)cc2CS(=O)(=O)O)C(C)CN1Cc1ccc(F)cc1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 +COC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(-c2ccccc2)n1 +Cc1nc(-c2nc3cnc(N4CCN(C)CC4)cc3n2Cc2ccccc2)cn2c(C)nnc12 +CN(Cc1cccs1)C1CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1 +O=C(c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(CN2CCCC2)CC1)C1CC1 +CC(CC(C)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C)C(=O)O +O=C(NCc1ncc(S(=O)(=O)c2ccccc2)cn1)c1cnc2nccn2c1 +COc1cc2c(C(=O)C3CSC(c4cccnc4)N3)cn(C(=O)N(C)C)c2cc1OC +COC1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)c2ccccc21 +CC1(C)c2ccc(C3=CCN(C4CC4)CC3)cc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +CCN(Cc1cnn(C)c1)C(=O)c1cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(C)c2[nH]1 +Cc1ccc(-c2nn(CCCCCCCN3CCN(c4cccc(Cl)c4)CC3)c(=O)c3ccccc23)cc1 +CCCc1[nH]c(-c2[nH]c3ccc(Cl)cc3c2S(=O)(=O)c2ccccc2)nc1C +O=c1[nH]c(=O)n(C2OC(CCP(=O)(O)O)C(O)C2O)cc1-c1ccc(F)cc1 +NC(CCC(=O)Nc1ccc(Oc2ccccc2)cc1)c1nnc[nH]1 +O=C(O)CNC(=O)Nc1cc2c(cc1Cl)[nH]c(=O)n1nc(C(=O)O)c(C(=O)O)c21 +CC1=C2CCc3cc(C(=O)Oc4ccc(F)cc4)ccc3N2CCC1=O +Cc1ccc2[nH]c3c4ccc5ccn(C)c5c4c4c(c3c2c1)C(=O)NC4=O +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(F)cc1 +CC(C)NC(=N)c1ccc(-c2cc3ccc(C(=N)NC(C)C)cc3o2)c(O)c1 +CN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc(NS(C)(=O)=O)c4)c3c2)CC1 +CC(C)c1cc(C(C)(C)C)cc(-c2ccc(-c3ccccc3)cc2)c1CO +CC1(C)CN(c2cncc(N3CCC4(CC3)CNC(=O)C4)n2)C1 +Cc1c(-c2nnc(C(C)c3ccccc3)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1cc(C)cc(Cn2cc(CCCCC(=O)NO)nn2)c1 +CN1CCN(C(=O)CC2CCCC3(C2)OOC2(O3)C3CC4CC(C3)CC2C4)CC1 +CC(Cc1ccccc1)n1c(-c2ncccc2C(F)(F)F)nc2ccnc(C(F)(F)F)c2c1=O +O=C(Nc1nc(C(F)(F)F)c(S(=O)(=O)Cc2ccc(Cl)cc2F)s1)c1ccccn1 +CC(C)N1CC(C(=O)N2CCN(C3(CNCc4ccccn4)CCCCC3)CC2)C(c2ccc(Cl)cc2)C1 +CCCCCNC(=O)Nc1c(C)cccc1CSCCn1cnc(-c2ccccc2)c1C +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3ncco3)nc21 +CC(C)CC(NC(=O)c1ccc(N2CCN(C)CC2)cc1)C(=O)N1CC(C)C2OCC(=O)C21 +O=C(O)C(Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)NC(=O)C1CCC(=O)N1Cc1ccccc1 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+Cn1c(SCCCN2CCOC(c3ccc(C(F)(F)F)cc3)C2)nnc1-c1cnccn1 +COc1ccc(C(=O)NNC(=S)NC(=O)c2ccc(Cl)cc2)cc1 +COc1ccc(-n2nc([N+](=O)[O-])c(NCCc3cccc(C)c3)[n+]2[O-])cc1 +O=C1NC(=O)C(c2ccc(-c3ccc4ccccc4c3)[nH]c2=O)(C2CCCC2)O1 +OC12Cc3c([nH]c4ccccc34)C3Oc4c(OCCCc5ccccc5)ccc5c4C31CCN(CC1CC1)C2C5 +CCCCCN(CCC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)nn(C)c12 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1C(=O)N1CCCCC1 +Cc1onc(-c2ccc(F)cn2)c1COc1ccc(C(=O)O)cn1 +CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(N4C5CCC4COC5)ccc3C(F)(F)F)cnc2N)CC1 +CN(c1ccc(NC(=O)Nc2ccccc2)cc1)c1ccnc(Nc2cccc(S(N)(=O)=O)c2)n1 +N#Cc1c[nH]c2ccc(C3CCCC3CN3CCCC3)cc12 +CC(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1c(Cl)cc(Cl)cc1Cl +COC(=O)CCC(C(=O)C=Cc1ccc(O)c(C(F)(F)F)c1)C(=O)C=Cc1ccc(O)c(C(F)(F)F)c1 +Cn1c(=O)n(C2CCN(C(=O)OC3C4CC5CC3CC(C(N)=O)(C5)C4)C2)c2c(Cl)cccc21 +CCOC(=O)c1cnc(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)s3)CC2)c(Cl)c1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1ccc(-c2ncc(CC3CC3)[nH]2)cc1 +CCN(CC)C(=O)c1nc2ccccc2c(-c2ccccc2)c1CI +O=C(Nc1cccc2ccncc12)C1CCC(N2C(=O)C3C4CCC(C4)C3C2=O)CC1 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+N=C(N)c1cc2c(OC(COC(=O)Nc3ccccc3CN3CCNCC3)c3ccccc3)cccc2s1 +NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)O)C1C(O)C(O)(CO)C(O)CN1O +COc1ccc(S(=O)(=O)Nc2nc(-c3cccc([N+](=O)[O-])c3)cs2)cc1 +Oc1ccc(-c2cc(-c3ccco3)nc3c2Cc2ccccc2-3)cc1 +NC(=O)c1ccc(-n2nc(C(F)(F)F)c3c(-n4cnc(-c5cccnc5)c4)ccnc32)cc1N +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C(=O)NC1CCNCC1 +CSc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c(CO)c3)cc2)cc1 +Nc1ccc2cccc(OCCNCc3ccc4c(c3)OCO4)c2n1 +Cc1c(C(O)CN2CCC3(CC2)CC(=O)N(c2ccc(S(C)(=O)=O)nc2)C3)ccc2c1COC2=O +CC(C)(C(=O)NO)c1csc(NC(=O)c2cccc(COc3ccccc3)n2)n1 +CCOCCNc1c(C(=O)OCC)cnc2c1cnn2CC(Cl)c1ccccc1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC(NC(=O)c1ccc[n+]([O-])c1)c1cccc(F)c1 +C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c1 +Nc1nsc2cccc(C(=O)Nc3cccc(CNC(=O)Nc4ccc(C(F)(F)F)cc4)c3)c12 +Cn1ccc2ccc3c4[nH]c5c(CCO)cccc5c4c4c(c3c21)C(=O)NC4=O +CC(=O)NCSCC(=O)NCC1CN=C(c2ccccc2F)c2ccccc2N1C +CCCCCCC[N+]12CCC(CC1)C(OC(=O)C1(O)c3ccccc3-c3ccccc31)C2 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+O=C1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CCN1 +Nc1ccccc1NC(=O)c1ccc(CNc2ncc(-c3ccc(Cl)cc3)s2)cc1 +CCN(CC)C(=O)C1CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C(NC(=O)c2nc3c(s2)CN(C)CC3)C1 +CCCCc1cc(NC(CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccc(F)cc3)c2)n1 +C1=C(c2ccc(CCN3CCCC3)cc2)C2CN(C3CCCC3)CC2C1 +O=C1C(=Nc2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCN2CCCC2)c1 +COc1cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)cc2F)ccc1F +NC(=O)c1cccc2c(NCc3ccc(N)cc3)ncnc12 +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)c2coc(C)n2)C(=O)O)c(C)c1 +NC1=NC(c2cc(NC(=O)C#Cc3ccccc3)ccc2F)(C(F)F)C2CC2O1 +Cc1[nH]c2cc(Cl)ccc2c1Sc1cccc(C(=O)O)c1 +CC(C)Oc1ccc(Nc2nc(=O)n(CCNC(=O)N(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F +CCCCCCCCCCCCCCCCCCOCCOP(=O)(O)COC(CO)Cn1cnc2c(N)nc(N)nc21 +CCNC(=O)c1cc2nccc(Oc3cccc(NC(=O)c4occc4C)c3)c2s1 +CNC(C)C(=O)Nc1cc(-c2cccc3cnn(C)c23)cc(C#Cc2ccc3c(c2)CC(=O)N3C)n1 +NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3ccccc3C(F)(F)F)c2)n1 +CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4C)n2)CN(C(C)=O)CC3)cc1 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+Clc1ccc2c(Nc3ccc(Nc4nc(NCCCN5CCOCC5)nc(Nc5ccccc5)n4)cc3)ccnc2c1 +N#Cc1cc(-c2nc(Nc3ccc(CN4CCOCC4)nc3)ncc2F)cnc1N1CCC(F)C1 +CC1C2c3cc(N4CCOCC4)ccc3CC(c3ccc(N4CCOCC4)cc32)N1C +O=C(C=Cc1cccn(CC=Cc2cccc(Br)c2)c1=O)NO +CCNC(=O)NCC1CC1c1c(Cl)ccc2c1CC(CCCCc1ccccc1)O2 +COc1cccc(Nc2c(C(N)=O)cnc3ccc(S(=O)(=O)c4ccc(C(C)(C)C)cc4)cc23)c1 +O=S(=O)(c1ccc(C(F)(F)F)nc1)N1C(C2CC2)c2cn[nH]c2C(F)(F)C12CC2 +Nc1nc(NC(=O)CCCC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1ccc(C(C(=O)NCCCN2CCC(C#N)(c3ccccc3)CC2)c2ccc(C)cc2)cc1 +CCCCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +Oc1cccc2c1OC1CCCC3CN(CCc4ccccc4)CCC231 +COc1cccc(CCCCN2CCN(c3ccccn3)CC2)c1 +CC1(O)CC(N)(c2ccc(-c3nc4n(c3-c3ccccc3)COc3ccc(-c5ccn[nH]5)cc3-4)cc2)C1 +CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(C(C)(C)CNCC(F)(F)F)cn1 +CCCCNC(=O)c1sc2nc(OC)c(Cl)c(C)c2c1N +CC1CCCC(C)N1CCCNC(=O)C(c1ccccc1Cl)c1ccccc1Cl +Cc1csc2nc(C(C)NC(=O)C=Cc3ccccn3)oc(=O)c12 +CC(c1cc(F)cc(Cl)c1)N(C(=O)c1ccccc1)C(C(N)=O)c1ccccc1 +O=C(CO)ONC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC2CCCCC2)C(=O)C(O)CO)c1 +CCOC(=O)C1CCC(Nc2cccc(Sc3ccc(C=CC(=O)N4CCOCC4)c(C(F)(F)F)c3C(F)(F)F)c2)CC1 +CC#CC(CC(=O)O)c1ccc(Oc2ccc(C(F)(F)F)c3ccccc23)cc1 +Cc1cccc(-c2ccc(CC(=O)Nc3cc(C4CC4)[nH]n3)cc2)c1 +NC(=O)CC(Nc1nc(-c2ccc(Oc3ccc(F)cc3)cc2)c2ccccc2n1)C(N)=O +NCc1cc(Oc2cccc(Oc3ccccc3)c2)nc(C(F)(F)F)c1 +CC(C)NCc1cc(C2(C)CCSC(N)=N2)c(F)cc1F +CNCc1nnc(-c2cn3ncnc(Nc4cc(C(=O)NC5CC5)c(F)cc4F)c3c2C(C)C)o1 +COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OC1COC2C1OCC2N1CCCC1 +Cc1ccccc1CC(=O)N1CCc2cc(-c3cn(C)c4ncnc(N)c34)ccc21 +O=C(O)Cc1cc(Br)c(Oc2ccc(O)c(Oc3cccc(C(F)(F)F)c3)c2)c(Br)c1 +Cc1cc(CCn2cc(-c3cccnc3)nc2Cn2c(=O)n(C3CC3)c3ccncc32)on1 +Cc1ccc(S(=O)(=O)N2c3ccccc3Oc3ccccc32)cc1 +COCCOc1cc(-c2ccc3nc(NC(C)=O)cn3c2)cnc1N +COc1cc2c(OC3OC(C)C(O)C(O)C3O)c3c(c(-c4ccc5c(c4)OCO5)c2cc1OC)C(=O)OC3 +O=C(C=Cc1ccoc1)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +CN(C)c1ccc(C=CC(=O)C=Cc2cccc(Oc3ccccc3)c2)cc1 +CCCC(c1ccc(C(=O)NCCC(=O)O)cc1)C(c1ccc(Cl)c(Cl)c1)c1csc2c(C#N)cc(Cl)cc12 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+O=C(CNCCn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1)OC1CCCC1 +Nc1nc(N)nc(NCCc2ccc(S(N)(=O)=O)cc2)n1 +CCC(COc1cc(Cl)cc(Cl)c1)OC(=O)NCc1ccccc1 +CCSC1=NS(=O)(=O)c2cc(C)cnc2N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COCCC(CC1(C(=O)Nc2nnc(Cc3ccccc3)s2)CCCC1)C(=O)O +O=C(Nc1ccc(N2CCC(N3CCCCC3)CC2)c(Cl)c1)C1(c2ccccc2)CCC1 +CC1(C)CC(=O)N(c2cc(Cc3nnc(O)c4ccccc34)ccc2F)C1=O +CNC(C)C(=O)NC1CC=CCC2C(Cc3ccccc3)CC(C(=O)NC3CCCc4ccccc43)N2C1=O +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc4c(c3)CC(=O)N4)nc2n1 +COc1cc2c(c(OC)c1OC)CC(Sc1nc3ccccc3[nH]1)C2=NN=C(N)N +O=C(Cn1c2ccccc2c(=O)c2ccc(Cl)cc21)Nc1cccc(Cl)c1 +NC(C(=O)N1CCCC1C(=O)NCc1cccc(O)c1)C(c1ccccc1)c1ccccc1 +CCc1c(COc2ccc(Cc3nnn[nH]3)cc2)ccc(C(C)=O)c1O +CCCCC1=NS(=O)(=O)c2ccccc2N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cc1ccccc1C(=O)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)c1ccc(Cl)cc1 +O=c1cc(C2CCNC(CCc3ccccc3)C2)o[nH]1 +CCN1CCN(C2(C(=O)N3CC(S(=O)(=O)c4ccccc4Cl)CC3C(=O)NC3(C#N)CC3)CC2)CC1 +Cc1cc(N2CCN(CCCO)CC2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 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+Cc1ccc2cc(-c3n[nH]c4ccc(NC(=O)c5ccco5)cc34)[nH]c2c1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccccc3F)CC2)nc2ccsc12 +CCCc1cc(N2CCC(O)CC2)nc2sc(C(N)=O)c(N)c12 +O=C(OCC#CCSc1nnc(-c2cccc3ccccc23)o1)C1CC1 +CC(NCCNc1ccnc2cc(Cl)ccc12)c1nc(Cc2ccccc2)c(N2CCOCC2)o1 +CC(C=CC(=O)NO)=Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 +CC(C)(C)c1ccc(C(=O)Nc2ccc3sc(CO)nc3c2)cc1 +CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1 +CCCCN1CCN(Cc2ccc(-c3ccccc3)cc2)C(CCO)C1 +CN(C(=O)Cc1ccccc1)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 +NCc1ccc(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(Cl)c(O)c(Cl)c4)cc23)cc1 +NCC1CCC(C(=O)NC(Cc2ccccc2)c2nc(-c3ccc(C(N)=O)cc3)c(Br)[nH]2)CC1 +CCCCc1nc(C)n(Cc2sccc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C1CCC2=C1C(c1ccc(F)c(Br)c1)C1=C(O)CSCC1=N2 +Cc1cc(C)n2nc(OCCO)c(S(=O)(=O)c3ccccc3)c2n1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1cccc(F)c1F +CCCc1nc(-c2ccc(Oc3ccc(CC(=O)O)cc3OC)c(NS(=O)(=O)c3ccc(Cl)cc3Cl)c2)n[nH]1 +O=C(NC1CCC(O)CC1)C1NC2(CCCCC2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(Cl)c1F +CCCCCCCOc1ccc(NC(=O)ON=Cc2ccc(F)cc2)cc1 +Cc1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1)=NC2 +CNc1ccc(Nc2nccc(-c3sc(C)nc3C)n2)cc1 +CCCN(CC1CC1)C(=O)c1c(C)nc2n(-c3c(C)cc(C)cc3C)c(Cl)cn12 +Cc1ccc(C2=C(n3cnnc3C)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +NCC(Cc1cccc(F)c1)NC(=O)c1cc(Br)c(-c2ccnc3[nH]ccc23)s1 +CC1CCCCN1CCCNc1ncc(C(=O)NCc2ccccc2)c(NCC2CCCCC2)n1 +CNC(=O)c1cccc(Nc2nccc(N3CC(Oc4ccc(F)cc4)C3)n2)c1 +O=C(NCc1ccccc1)NC12CC3CC(CC(C3)C1)C2 +COc1cccc(C(=O)c2cc(C(=O)C(F)(F)F)n(-c3cnn(O)c3)c2)c1 +Brc1ccc(Br)c2c1C1CC(c3ccoc3)(c3ccoc3)C2c2cccc[n+]21 +Cc1noc(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 +C=COC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)CCCCCNC(=O)OCc1ccccc1)C(C)C +CN(C)C=Nc1nn(-c2ccc(C(=O)O)cc2)cc1C#N +CC#CCOc1cccc2c1-c1cccc3c1C(C2)N(CCC)CC3 +Cc1cn(-c2ccnc(Nc3cc(C)c(OCC(=O)N4CCCC4)c(C)c3)n2)cc1CN1CC(O)C1 +CCOc1cc(NS(C)(=O)=O)c(OCC)cc1CNC(=O)Nc1ccc(OC)cc1 +Cc1ccc(C=Cc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4cccs4)cc23)cc1 +CCC(=O)N(Cc1ccc(OC)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 +CC(C)C1C(=O)N(c2ccccc2)C(=O)N1Cc1ccc(C(=O)NO)cc1 +O=P(OC1CCCC1)(c1ccccc1)N1CCCC(c2ccc(Cl)c(Cl)c2)=N1 +Cc1cc(C(=O)N2CCC3(CC2)Cc2cnn(C(C)(C)C)c2C(=O)N3)cc2c[nH]nc12 +Cc1nc(Cc2cccc3ccccc23)c(CCC(=O)O)c(C=O)c1O +Cn1c(-c2c(N)n(C3CCCC3)c3nc4ccccc4nc23)nc2ccccc21 +CC1CCC(NC2=NC(=Cc3c[nH]c4ncccc34)C(=O)N2)CC1 +Cc1cc(C)cc(Oc2c(C(C)C)c(=O)[nH]c(=O)n2CC2CCCCC2)c1 +COc1ccc(Br)cc1CCc1ccccc1-c1nc(C)cn1C +CCOc1ccc(-n2c(C(C)N(Cc3cccnc3)C(=O)Cc3ccc(OC(F)(F)F)cc3)nc3cnccc3c2=O)cc1 +COc1ccc(-c2ccc(N3CCC4CN(C)CC43)cc2)cc1 +CC(C)(O)C(NC(=O)N1CCN(c2ccc(-c3ccccc3)cc2)CC1)C(=O)NO +COc1ccc(Cn2c(C)c(C)c3cc(C(=O)NC(C)c4ccc(C(C)(C)C)cc4)ccc32)cc1OC(C)C(=O)O +O=c1[nH]c2nc(NC3CCOCC3)ncc2cc1Oc1ccc(F)cc1F +CN(CCc1ccc2c(c1)OCO2)C1CCCCC1N1CCCC1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2C)nc1-c1ccccc1F +CC(NS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1)c1ccccc1CC(=O)O +Cc1ccc(Cl)cc1-n1c(-c2ccccc2)nc(C(=O)O)c1-c1cccc(Cl)c1 +CC(=O)NC1CC2CCC(C1)N2C(=O)c1ccc(Nc2nc(-c3sc(C)nc3C)cs2)nc1 +CC1CN(c2nnc(C(F)(F)F)o2)CCN1c1ncc(OCc2ccc(S(C)(=O)=O)cc2F)cn1 +O=C(CCc1ccc(O)cc1)N(Cc1nc2c(c(=O)[nH]1)COCC2)Cc1cccs1 +CC(=O)Nc1cc(Nc2cc(NC3CC3)n3ncc(C#N)c3n2)c(F)cc1C +C=C(c1ccc(S(=O)(=O)c2ccc(OC)cc2)cc1)C1CCN(C2CCN(C(=O)CCC)CC2)CC1 +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)N4CCNCC4)c4ccc(C)cc34)cc2)c1C +Cc1cc(S(C)(=O)=O)cc2c1N(C(=O)OCCC1CCN(C(=O)OC(C)(C)C)CC1)CC2 +O=C(Cc1ccc(F)cc1)NC(=O)Nc1ccc(Oc2ccnc3[nH]cc(C(=O)CN4CCC(O)C4)c23)c(F)c1 +CN1C2CCC1C(C(=O)OCCc1ccc(N)c(I)c1)C(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3ccc(F)cc3NC(=O)c3cnc4ccccc4c3)cc1)CC2 +O=C(NCCCN1CCOCC1)c1c[nH]c2ccc(S(=O)(=O)N3CCc4ccccc43)cc2c1=O +OCC1CCCN1c1ncnc2sc(Nc3cccc(Br)c3)nc12 +CN1C(=O)CCc2cc(-c3cncc(COc4ncccn4)c3)ccc21 +C=C(CN(C)C)C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(C#N)cnc2cc1OCC +CCCC1(CCc2ccc(O)cc2)CC(=O)C(Sc2cc(C)c(N)cc2C(C)(C)C)=C(O)O1 +CN(CCCCN1C(=O)C2Cc3ccccc3CN2C1=O)Cc1ccccc1 +COc1cc2c(N)nc(N3CCN(C(=O)CC(N)c4ccoc4)CC3)nc2c(F)c1OC +CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2OC(F)(F)F)(c2ccccn2)CC1 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+O=C(Nc1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cccc([N+](=O)[O-])c1 +CCc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(O)c(O)c3)[nH]c(=O)c12 +CC(C)(C)c1ccccc1N1CCN(C(=O)NCC(=O)O)CC1 +CC(C)(C)OC(=O)NC(C(=O)N1CCCC1C(=O)NC(C=O)CCCN=C(N)N)c1cccc2ccccc12 +Cc1oc(-c2ccccc2)nc1CCOc1cccc(C2CN(C(=O)Oc3ccccc3)CCC2CC(=O)O)c1 +Cc1ccc2nc(NC(=O)CSc3nc4c(c(=O)n3-c3ccccc3)SCC4)sc2c1 +O=c1[nH]ccc(NC2CCC(NCC(F)F)CC2)c1-c1nc2ccccc2[nH]1 +Clc1cc(-c2c[nH]c3ncccc23)nc(NC2CCCCC2)n1 +O=C(O)c1ccc2cc(-c3ccc(CC(O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 +Nc1nc(NCc2ccc(C(=O)Nc3ccccc3N)cc2)c2nc[nH]c2n1 +O=C(C=Cc1ccc(O)c(O)c1)NCCNc1c2c(nc3ccccc13)CCCC2 +CCOc1ccccc1N1CCN(CCCCc2cc(-c3cccs3)no2)CC1 +CC12CCC3c4ccc(O)cc4CCC3C1CC(CCCI)C2O +CCn1ncc(C(=O)N2CCC(Nc3cc(=O)[nH]c4ccc(F)cc34)CC2)c1Cl +CCCn1c(=O)c2nc(-c3cnn(Cc4cccc(Cl)c4)c3)[nH]c2n(CCC)c1=O +CCCCc1nnc(C(=O)NCc2ccccc2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)N1CC(F)(F)C1 +Cc1cc(C)cc(C(=O)N2CCN(C(=O)CNC3CCNCC3)C(c3ccc(Cl)c(Cl)c3)C2)c1 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+COc1ccc(S(=O)(=O)NC(C)CCN2CCN(c3cccc(C(F)(F)F)c3)CC2)cc1 +O=C(O)CCC(O)c1ccc(OCc2cccc(Br)c2)cc1 +Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4CCC([S+]([O-])C(C)(C)C)C4)cc3)nn3cccc23)n[nH]1 +COC(=O)C1CC(OC(=O)C=C(C)C)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +CC1CCCN1C(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C +O=C1CC2(C=CN1CCN1CCN(c3cc(Cl)ccc3Cl)CC1)CCCC2 +COc1cccc2c1C(=O)c1c(OC)cc(C[N+](C)(C)C)cc1C2=O +CNc1cc(N2CCC(C(=O)NCc3ccccc3C(F)(F)F)CC2)nc(C)n1 +CN(C)CCNC(=O)C(CC(=O)Nc1ccc(Br)cn1)NC(=O)c1ccc(-c2ccccc2S(N)(=O)=O)cc1 +CN(C)C(=O)c1c(CNC(=O)c2ccc3c(c2)OCCO3)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +Oc1ccc(C2Sc3cc(O)ccc3OC2c2ccc(OCCN3CCC(O)CC3)cc2)cc1 +O=C1C(c2ccccc2)=COC12CCN(CCc1ccccc1)CC2 +CCCN1CCN(Cc2ccc(S(=O)(=O)Nc3cccc(C)c3)cc2)CC1 +CCOc1nn2c(=N)n(CC(=O)c3cc(OCCO)cc(C(C)(C)C)c3)nc2c(CC)c1C +O=C(c1ccnc(F)c1)N1CC2(CCN(CC=Cc3ccc(Cl)cc3)CC2)c2cc(F)ccc21 +COc1ccc(N(C(=O)c2ccoc2C)C(C(=O)NCC(C)O)c2ccccc2F)c(OC)c1 +CN1CCN(c2ccc(-c3nc4ccc(I)cc4s3)cc2)CC1 +CCC(CO)Nc1nc(NCc2cc(Cl)ccc2O)c2ncn(C(C)C)c2n1 +COc1ccc2cc(CNCCc3ccc(Br)cc3)c(-c3ccccc3)nc2c1 +Nc1cc(C(=O)N2CCOCC2)cc(-c2cnc3[nH]cc(-c4ccncc4)c3c2)c1 +NS(=O)(=O)c1ccc(-n2cc(COC3OC(CO)C(OC4OC(CO)C(O)C(O)C4O)C(O)C3O)nn2)cc1 +CCN(CC)CC(=O)Nc1cccnc1C(=O)Nc1nccs1 +CCCCCCCN(C=O)C1CCC2C3CCC4N(C)C(=O)CCC4(C)C3CCC21C +O=C1c2ccccc2-c2nnc(-c3ccc(Cl)cc3)cc21 +Nc1cc(Cn2c(C(=O)O)c(-c3ccc[nH]c3=O)c3cc(-c4cccc(=O)[nH]4)ccc32)ccn1 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1cnc(N)nc1 +COc1cc(C2=C(c3cn(C)c4ccccc34)C(=O)NC2=O)cc(OC)c1OC +Cc1ncc(-c2cc3ncn(C)c(=O)c3c(NC(C)C)n2)s1 +O=c1c2c(oc(O)c1C(c1ccccc1)c1ccccc1)CCCCCC2 +CN(C)C(=N)c1ccccc1-c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 +CC1CN(c2ncccc2Cl)CCN1c1nc2ccc(C(C)(C)C)cc2[nH]1 +N#Cc1cc(S(=O)(=O)Nc2nncs2)ccc1Oc1ccc(Cl)cc1-c1ccnc(N2CCOCC2)c1 +CC1CCCN1C(=O)CN1CCCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O +COc1cc(C(C)=O)ccc1OCCCN1CCC(C(c2ccccc2)c2ccccc2)CC1 +CS(=O)(=O)N1CCCC(c2csc(-c3ccccc3NC(=O)c3nc(Cl)c[nH]3)n2)C1 +CC(C)CC(NC(=O)COc1ccccc1-c1ccccc1)C(=O)NC1CC(=O)OC1O +C=C(C)CN(C1Cc2cc(C#N)ccc2N(Cc2cncn2C)C1)S(=O)(=O)c1cccnc1 +COc1cccc2c1CCCC2C(=O)NCCCN1CCN(C2CCCCC2)CC1 +Cc1cc(C(C)Nc2ccccc2C(=O)O)c2nc(N3CCOCC3)cc(=O)n2c1 +O=S(=O)(NCC(F)(F)F)c1ccc2c(c1)CNC(CO)C2 +CC1CCCN1S(=O)(=O)CC1CCC(N(C)c2ncnc3[nH]ccc23)CC1 +CN(C)CC(Cc1ccccc1)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COc1cc(Cl)ccc1N1CCN(CCn2cnc3sc4c(c3c2=O)CCN(C)C4)CC1 +O=c1[nH]c(=S)[nH]c2c(-c3ccc(I)cc3)cnn12 +Cc1ccoc1C(=O)Nc1cccc(C#Cc2cncc(C(=O)N=S(C)(C)=O)c2)c1 +NS(=O)(=O)c1ccc(NC(=O)NNS(=O)(=O)c2ccc(Br)cc2)cc1 +Cc1ccc(S(=O)(=O)N(Cc2nnc(Cc3cccc(Cl)c3)o2)c2cccc(Cl)c2C)cc1 +COc1ccc2c(c1)cc(-c1ccsc1)n2Cc1cccc(C(=O)O)c1 +Cc1cc(C)c2nc3c4cccnc4c(=O)cc-3oc2c1 +COC(=O)C=Cc1ccc2c(c1)c1cccc3c1c(c1ccccc1n3C)[n+]2C +[O-][n+]1c(Cl)c(C(F)(F)F)cc2nc(O)c(O)nc21 +C=CC(=O)NC1CCN(S(=O)(=O)c2ccc(Nc3ncc4c(n3)N(C)c3ccc(C)cc3C(=O)N4C)cc2)CC1 +CCc1cc(-c2ccccc2)cc(CC)[n+]1CCc1ccc(S(N)(=O)=O)cc1 +CCCCCCCCCC=C(NC(=O)C1CC1(C)C)C(=O)O +[O-][n+]1nc2c(F)cnn2c2cc(OCc3cccs3)ccc21 +COc1cccc(-c2ccc(CNC(=O)C3CC3c3ccccc3)c3c2CCN(C(C)=O)C3)c1 +CCCCN(CCCOc1ccc(S(=O)(=O)c2c(C(C)C)cn3ccccc23)cc1)CCc1ccc(OC)c(OC)c1 +CN1CCC12CCN(C(=O)OC1(C3COCC(CC4CC4)N3S(=O)(=O)c3ccc(Cl)cc3)CC1)CC2 +CC(C)(C)C(O)C(=O)NS(=O)(=O)OCC1CC(n2cnc3c(N)ncnc32)C(O)C1O +CC1NC(c2cccc(S(C)(=O)=O)c2)=NC1(c1ccc(F)cc1)c1ccc(F)nc1 +Cc1cc(C)c(-c2[nH]c(C3CCOCC3)nc2C#N)cc1C(=O)N1CC(c2ccc(C#N)cc2)C1 +CCC(C)C1OC(c2c(O)c(-c3ccccc3)cn(O)c2=O)C(C)CC1C +Cn1cnc(S(=O)(=O)N(CCN(Cc2cncn2C)c2ccc(Br)cc2)Cc2ccccc2)c1 +CC(NC(=O)c1ccc(C#N)n1C)c1c(F)cccc1Cl +Clc1ccc(CN2CCC(NC3C4CC5CC(C4)CC3C5)CC2)cc1 +N#Cc1ccc2[nH]cc(C3CCC(N4CCCCC4)CC3)c2c1 +NS(=O)(=O)Nc1ccc(S(=O)(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +CCN1CCN(c2ccc(NC(=O)c3ccc(-c4ccncc4)cc3)cc2)CC1 +CCOc1ccc(N(C)c2nc(C)nc3oc(C)cc23)cc1 +CCN1C(=O)c2c(nc(I)n2Cc2ccc(O)cc2)N2CC(Cc3ccccc3)N=C12 +CN(CCN1CCN(c2ccccc2)CC1)c1cccc(NS(C)(=O)=O)c1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)c2n1CCSC2)c1ccccc1 +CS(=O)(=O)NC(=O)c1cc(C=Cc2cn3nc(Cl)cc(N4CCOCC4)c3n2)nc2ccccc12 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+COc1ncnc2c1c1ccsc1n2C1OC(CO)C(O)C1O +NC(=O)C1C[S+]([O-])CN1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 +Cc1ccc2c(c1)n1ncc(C(=O)Oc3cccs3)c1n[n+]2[O-] +CC(NC(=O)Nc1cc2[nH]nc(OCc3ccccn3)c2cn1)c1ccc(F)cc1 +N#CCC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 +O=C1Nc2cccc(Cl)c2CN1c1csc(-c2ccncc2)n1 +O=[N+]([O-])c1ccc(-c2nnn(-c3ccc(Cl)cc3)n2)o1 +COc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc(Cl)cc2)ccc1OCCn1c(=O)ccn(C)c1=O +Cc1ccc(C(=O)Nc2ccc(C(=O)N3CCC4(C=CCCC4)Cc4ccccc43)cc2)cc1C +COc1ccc(COc2ccc(-c3nn(CC(F)(F)F)cc3-c3ccncc3)cc2)nc1 +CC1COCCN1c1cc(C2(S(C)(=O)=O)CC2)nc(-c2ccc(NC(=S)NCCO)cc2)n1 +CC1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1c[nH]c2c(-c3ccsc3)ccnc12 +Cc1ccoc1C(=O)Nc1cccc(Oc2ccnc(-c3cc(C(=O)NO)c[nH]3)c2)c1 +Nc1nc(-c2ccn3c(-c4cc(NC(=O)NCC(F)(F)F)ccc4F)cnc3c2)ncc1F +CCCCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1cccc(NC(=O)NC2C(=O)N(CC34CC5CC(CC(C5)C3)C4)c3ccccc3N(c3ccccc3)C2=O)c1 +COc1ccc2c(c1)CCN(S(N)(=O)=O)C2c1ccc(S(N)(=O)=O)cc1 +Cc1cccc2[nH]c(=O)n(C(=O)OC3CC4CCC(C3)N4C)c12 +O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccccc3)cc2-c2ccc([N+](=O)[O-])cc2)cc1 +COC(=O)C1=Cc2c(ncnc2Nc2ccc(Oc3cccc(C(F)(F)F)c3)c(Cl)c2)NCC1 +CC(O)(C1CCN(c2nccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1)C(F)(F)F +CN(C)CCNC(=O)c1cccc2c(N)c3cccc(S(C)(=O)=O)c3nc12 +Cc1nc(CN2CCC(Oc3ncnc4c3ccn4Cc3ccccc3)CC2)cs1 +Nc1ncnc(N2CCC(c3nc(-c4ccnc(C(F)(F)F)c4)cn3CCNCCCCl)CC2)c1Br +CN(C)C12CCN(CCN3CCCC3)C(C(c3ccccc3)C1)C(c1ccccc1)C2 +O=C(C#CCCN1CCCCC1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cn1 +CCNc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +COc1ccc(C(=O)N2CCN(c3ccc(NC(=O)N4Cc5ccccc5C4)cc3)CC2)cc1 +CCN(CC)CCN(C(=O)c1cccc([N+](=O)[O-])c1)c1nc2ccc(OC)cc2s1 +CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3C#N)CC2)C(c2ccc(F)c(F)c2)NC(=O)N1C +CCCCS(=O)(=O)N(Cc1ccc(F)c(F)c1)c1cc2ccccc2s1 +Cc1cc(C(=O)NC(Cc2cccc(Cl)c2)C(=O)NCC#N)c2cc(C)ccc2c1 +CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccc(Cl)cc1n2CCOCCOCCF +CC1CN(c2ccccc2)CCN1C(=O)C1CCCCC1C(=O)NCC#N +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5Cl)CC4)cc3)cc2n(C)c1=O +CCCOC(=O)C1=CC2C(CC(OC(=O)C=Cc3cn(C)cn3)C3(C)C=CC1(OC)O3)C(C)=CCC2C(C)C +[C-]#[N+]c1ccccc1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C +CCC12CCC(=O)C=C1c1c(cc(OCC(=O)OCC(=O)O)c(Cl)c1Cl)C2 +CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(C(C)(C)CF)[nH]2)c1O +CC(C)c1cccc(C(C)C)c1NC(=O)NC1CCc2ccccc2C1 +CCc1nnc2c(NC3CCCCC3)nc3ccc(Cl)cc3n12 +CN(C)C(=O)c1c(CNC(=O)c2cnc(N3CCC(CO)CC3)s2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +FC(F)(F)c1ccc(Nc2nc(CN3CCOCC3)nc3cc(-c4ncccc4C(F)(F)F)ccc23)cn1 +CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1)B(O)O +O=C1CCC(c2cccc(C(=O)N3CCOCC3)c2)(C2CCN(Cc3ccc(Br)cc3)CC2)C(=O)N1 +CCC(CC)Oc1cccc(N(Cc2cccnc2)S(=O)(=O)CC(F)(F)F)c1 +CC(C)(CCl)Cn1c(-c2ccc(P(=O)(O)O)o2)nc2c(N)ncnc21 +N#Cc1ccc2sc(C(=O)NC3CCN(Cc4ccc(OC5CCNCC5)c(Br)c4)CC3)cc2c1 +CCCCC(C(=O)NO)C(=O)N1CCCC1c1nc2ccccc2o1 +CN1CCC23c4c5ccc(C(N)=O)c4OC2C(O)C=CC3C1C5 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +Cc1ncnc(C)c1C(=O)N1CC2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)CC(F)(F)F)CC3)CC2C1 +O=C(Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)c1Cl)c1ccccc1F +CCOC(O)=C1C(Cn2ccnc2)=NC(Cn2ccnc2)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1 +OCC1OC(n2ccc3c(-c4c[nH]cn4)ncnc32)C(O)C1O +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3CC3CCCCC3)ccc2[nH]1 +CCOC(=O)c1ncn2c1Cn1ncnc1-c1cc(NC(=O)C(C)C)ccc1-2 +Cc1cnc(Nc2cccc3[nH]ccc23)c(-c2nc(C)nc(N)n2)c1 +CCn1ncc2cc3nc(c21)CCCOCC(c1ccccc1)NC(=O)N3 +CCc1cc(C2C(c3ccc(C)cc3)CC3CCC2N3C)on1 +CCc1ccc(Oc2ccc(Cn3c(=O)oc4ccc(OCC(=O)OC)cc43)cc2)cc1 +CCC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl +Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4cccs4)cc3=O)cc21 +CCn1c(CNc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCC(=O)O)c3cc(C)ccn3)ccc21 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2c(F)cccc2F)c1 +O=C(O)CCC(Cc1ccccc1)NC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)N1CCC2(CCCC2)CC1 +CNc1nc2c(N)ncnc2n1C1OC(CN(C)CCCCON)C(O)C1O +COc1ccc(NC(=O)Nc2nc3nn(Cc4cccc5ccccc45)cc3c3nc(-c4ccco4)nn23)cc1 +COc1c(C(=O)NCCN2CCCCC2)n(C)c2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21 +CS(=NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Br)cc1)c1ccccn1 +Fc1ccc(NCc2ccccc2)cc1-c1c(Cl)cnc2[nH]c(C3CCNCC3)cc12 +Fc1ccc(CNCCCCCCNCCCCCCCCNCCCCCCNCc2ccc(F)cc2)cc1 +O=c1c(C(c2cnc3ccccc3c2)c2c(O)oc3ccccc3c2=O)c(O)oc2ccccc12 +COc1ccc(CN(C)CC(O)COc2ccc(-c3ccccc3)cc2)cc1OC +CN(C)CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(NCCCN1CCCC1=O)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +COc1ccc(-c2nc(NC(=O)Cc3nn(C)c(=O)c4ccccc34)sc2C)cc1 +N#Cc1ccc(Nc2cc(Oc3c(Br)cc(Br)cc3Br)c(=O)[nH]n2)cc1 +CC(CCC(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1 +COCCN(C)S(=O)(=O)Nc1cc(Nc2ncc(Cl)cc2-c2nc(C)nc(N)n2)cnc1Cl +Cn1c(CNc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCCC(=O)O)c3ccccc3)ccc21 +C=CCOC(=O)N1CCCc2cc(S(=O)(=O)N3CC(c4ccccc4)NC3=O)ccc21 +COc1cc2nccc(Oc3ccc4oc(Nc5ccc(Cl)c(CN6CCN(C)CC6)c5)nc4c3)c2cc1OC +CC1CCC(C(=O)N2CCc3nc(C#Cc4ccccc4)sc3C2)CC1 +CC1(c2ccccc2)CCN(c2ccc(Cl)cc2)C(=O)O1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(-n2cccc2)cc1 +O=C(O)C1CN(Cc2ccc(-c3noc(C(F)(F)C(O)C4(c5ccc(Cl)cc5)CC4)n3)cc2)C1 +COc1cc(COc2cc3nccc(C(=O)O)c3[nH]2)ccc1Cl +COCCCCCCCC=C1CC(CO)(COC(=O)C(C)(C)C)OC1=O +O=C(Nc1ccc(Cl)c(Cl)c1)N1CCN(CC2CCCN(CC3CC3)C2)CC1 +CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(C)(C)C)c3cc(C(=O)O)ccc32)cc1 +CC(C)CNC(=O)c1cnc(NCCCN)nc1NC1CCCC1 +COc1cccc(CNCC(C)Oc2cccc3ccc(N)nc23)c1 +CNc1cc(Nc2cnc(C#N)c(OC3CCNC3)n2)ncc1C(=O)OC +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4c(Cl)cccc4Cl)nc23)N1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(NCCN(C)C)nc3)NC(=O)NC1=O)C2 +O=C1c2ccccc2C(=O)N1CCCN1CCN(Cc2ccccc2)CC1 +CC(C)(C)Nc1cc(NCC2CCOCC2)c2ncc(-c3ccc(C(=O)NC4CC4)cc3)n2n1 +N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC3COc3cccnc3)cc21 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(C(O)(O)C(F)(F)F)cc3)NC(=O)NC1=O)C2 +CCCC(=O)Nc1cc(-c2ccoc2)nc(-c2ccoc2)n1 +N=C(N)NOCCCOc1cc(Cl)cc(C(=O)N(CCc2cccnc2)CC2CC2)c1 +O=C(NS(=O)(=O)c1ccccc1)c1nc2cc(Cl)c(Cl)cc2nc1O +COC(=O)c1cccc(NC(=O)Nc2cccc(C(C)=O)c2)c1CN1CCC(Cc2ccc(F)cc2)CC1 +CN1C(=O)C(NC(=O)C(c2ccc(F)cc2)C(CO)c2ccc(F)c(F)c2)N=C(c2ccccc2)c2ccccc21 +COc1cccc(N2CCC(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)(c3cccc(OC)c3)CC2)c1 +C=CC(=O)Nc1ccc(CNc2nc(Nc3cnn(CC(=O)NC)c3)ncc2Cl)cc1 +COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3)c2cc1OC +COc1ccc(OC)c(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1OC +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCCCc1ccccc1 +COCc1cc(OC)c(-c2csc3c(N(CCCF)c4cccnc4)c(OC)nn23)c(OC)c1 +COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(OCCO)cc2)ccc1O +CC(O)COc1ccc2c(c1)CCC1(CCN(C3CCC3)CC1)O2 +COC1COCCC1NC1CC2OC(C)CC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1=O)NCc1ccccc1 +COc1ccc(C(C)(O)c2nc(C)nc3ccccc23)cc1 +COc1ccc(C=C2CN(C(=O)CN)Cc3c(C(=O)NC(C)c4ccccc4)nn(-c4ccc(Cl)cc4Cl)c32)cc1 +CC(C)C1CN(C2CCNCC2)C(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1 +CCCCC(C)c1nnc(-c2nc(-c3ccc(Cl)cc3Cl)n(-c3ccc(Cl)cc3)c2C)s1 +N#Cc1cc(-c2ccnc(Nc3ccnc(N4CCOCC4)c3)n2)cnc1N1CCC(F)C1 +N#Cc1cccc(NC(=O)Nc2ccccc2C(O)CN2CCC(Cc3ccccc3)CC2)c1 +CS(=O)(=O)c1ccc(-c2nc3c(s2)CN(C(=O)CC(N)Cc2cc(F)ccc2F)CC3)cc1 +O=C(NCCc1c[nH]c2ccc3c(c12)CCNC3=O)c1cccnc1 +COc1cc(-c2cc(C)c(=O)n(C)c2)c(OC)cc1CN(C)C 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+N#Cc1ccc(N2N=C3c4ccc(C(=O)O)cc4CCC3C2C2CCC2)cc1Cl +CN(C)C(=O)CN1CCC=C(c2[nH]c3nccc4c3c2CN(C)c2ccc(F)cc2-4)C1 +O=C(NC(CO)c1ccc(Cl)cc1)c1cc(-c2[nH]ncc2-c2cccc(Cl)c2)c[nH]1 +CCCC(=O)c1cnc2c(F)cccc2c1Nc1ccc(O)cc1C +CNc1nc2c(cc(C(=O)N(C3CC3)C3CC3)n2CCCO)c2c1ncn2C +CNCCN(C)Cc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2O)cc1 +CCc1ccc(-n2nnc(C(=O)Nc3ccccc3Cl)c2C)cc1 +CC(C)CN(CC(C)C)c1c([N+](=O)[O-])cc(S(N)(=O)=O)cc1[N+](=O)[O-] +CC1(C)OC(S)=Nc2ccc(-c3cccc(C#N)c3)cc21 +COC(=O)CCC(=O)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)CC1CCCCC1 +Cc1cc(S(=O)(=O)n2cc(-c3ccco3)[nH]c2=O)ccc1NC(=O)OC(C)C +CCC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(OC)c3)cc2c1Nc1ccc(CN(C)C)cc1 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(Cl)cc1 +COc1cc2c(N3CCN(C(S)=Nc4ccc(-c5cccc[n+]5[O-])cc4)CC3)ncnc2cc1OCCN1CCCCC1 +COc1ccc2c(c1)sc1nc(C)c(C)c(C)[n+]12 +CC(c1ccc2[nH]c(=O)sc2c1)c1ccn(-c2ccc(CCC(C)(C)O)cn2)n1 +O=C(Cc1ccccc1)Nc1ccc2c(c1)CC(=O)N(O)C2=O +O=C(NCCN1CCOC1=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)c1OC +COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1ccc2c(c1)OCO2)c1cn(C)c2cc(C#N)ccc12 +Cc1noc(C)c1-c1ccc(CNS(=O)(=O)c2c(C)noc2C)cc1 +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NO)c[nH]4)c3)cc2F)c1 +CC(C)NC(=O)Nc1c(C#N)cnn1CC(O)c1ccccc1 +COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cccc(Cl)c1F)C2=O +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CNCC(C)(C)O1 +Cn1c(=N)n(CCOc2ccc(Cl)cc2)c2cccc(Cl)c21 +COc1cc(-c2ccc3ncc(S(C)(=O)=O)c(NC4CCC(CN(C)C)CC4)c3c2)cc(Cl)c1O +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2C)c1 +CCCCOCC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 +NN(C(=O)c1ccc(Cl)cc1Cl)S(=O)(=O)c1ccc2c(c1)OCO2 +O=C(NCc1nc(Cc2ccccc2)co1)C(O)C(O)C(=O)N1CCCC1c1ccccc1 +CC1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1c[nH]c2c(-c3ncon3)ccc(F)c12 +O=C(C1Cc2ccccc2CN1C(=O)CCCc1ccccc1)N1CCCC1 +CC(C)n1c(=O)n(C(=O)NC2CCNCC2)c2ccccc21 +CC(c1ccc(F)cc1)N(Cc1cccc(C(=O)O)c1)C(=O)c1cn2ccccc2n1 +Nc1nc(N)c2nc(CN3c4ccccc4C=Cc4cc(OCCC(=O)O)ccc43)cnc2n1 +Nc1ncnc2c1ncn2C1OC(COS(=O)(=O)NC(=O)C2CCN2)C(O)C1O +Cc1nn(Cc2ccc(-c3nc4cc(Cl)ccc4n3C)cc2)c(C)c1CC(=O)O +COC(=O)C1CC(NC(=O)c2ccc(OC)cc2OC)CN1Cc1ccc(C(F)(F)F)cc1 +COc1cc(CN2CCCCC2)ccc1NC(=O)Nc1cnc(C#N)cn1 +CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCCC2(O)CCNCC2)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CCNC4)ncc23)ccn1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(N4CCC(O)C4)nc23)N1 +OCC1CCN(c2nccnc2C2CN(c3ccc4cccc(F)c4n3)C2)CC1 +CN(C)c1nc(NCC2CCC(CNS(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12 +COc1cccc(-c2cc(NCc3ccccc3)nc(NCC3CCC(C(N)=O)CC3)n2)c1 +CN1CCN(c2ccc(Nc3nc4c(-c5nnc[nH]5)cccc4c4cnccc34)c(Cl)c2)CC1 +O=C(c1cccc2ccccc12)N(CCN1CC=C(c2ccccc2)CC1)c1ccccn1 +CC(C)CN(C(=O)C(C)(C)C)c1cccc(C(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)c1 +O=C(Nc1cc(-c2ccccc2)c2ccccc2n1)C1CCCN1C(=O)CC1CCCC1 +CN(C)Cc1ccc(C2Nc3cc(F)cc4c(=O)[nH]nc(c34)C2c2ccc(F)cc2)cc1 +CC1CN(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)CCN1C(=O)OC(C)(C)C +O=C(O)c1ccc(S(=O)(=O)N(CCOC2CCCCC2)c2sc3ccccc3c2Br)cc1 +CC(CC=Cc1ccc(C(=O)C(F)(F)F)cc1)CCC1OC1(C)C +CN(C)c1ccc(C=C2CC3(O)C4Cc5ccc(O)c6c5C3(CCN4CC3CC3)C(O6)C2=O)cc1 +Cc1nsc(-c2ccc(N3CCN(c4ccc(C(F)(F)F)cc4)CC3)nn2)n1 +O=C(c1cc(Cc2c[nH]c(=O)c3cccn23)ccc1F)N1CCCNCC1 +COc1ccc(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)cc1 +CCCc1cc(-c2noc3ccccc23)ccc1OCCCOc1cccc(C2SC(=O)NC2=O)c1 +NC(CCc1cnc(Cl)c(C=Cc2ccncc2)c1)Cc1c[nH]c2ccccc12 +CC(C)CN(NC(=O)C(C)(C)c1ccc(CN2CCN(C)CC2)cc1)c1nc(C#N)ncc1Cl +COC1(NC(=O)Cc2ccc(O)cc2)C(=O)N2C(C(=O)OCc3ccc(C)cc3)=C(CSc3nnnn3C)COC21 +CSC1CC(C(=O)O)N(C(=O)C(C)NC(CCc2ccccc2)C(=O)O)C1 +CN1CCNc2nc(CCOc3cc(CC(CC(=O)O)c4ccc5c(c4)OCO5)on3)ccc21 +CCOc1cc(Cl)c(CS(=O)(=O)C2=NOC(C)(C)C2)cc1Cl +COc1c(Cl)cc(Cl)c(O)c1C(=O)NCC1CCCN1CCF +CCCCOc1ccc2c3cc[n+]4nc(CC)c(CC)cc4c3n(C(=O)OC(C)(C)C)c2c1 +COc1cccc(N2CCCCC2)c1CNC(N)=NC(=O)c1ccc(CC(N)C(=O)O)cc1 +Cc1c(-c2ccccc2)n[nH]c1C1=CCN(CCc2ccccc2)CC1 +Cc1cccc(-c2c(-c3ccncc3)nnn2CC(=O)Nc2ccc(-c3ccccc3)cn2)c1 +CCN1CCC2(c3cccc(O)c3)Cc3[nH]c4ccccc4c3CC2C1 +CC(=O)NCc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc2)cc1 +CN(C)CCn1ccc2cc3c(Nc4cccc(Br)c4)ncnc3cc21 +CN1CCc2nc(C(=O)NC3CCC3NC(=O)c3cc4cc(Cl)ccc4[nH]3)sc2C1 +N#CCc1c(C(=O)N2CCC(c3ncccn3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +CNC(=O)Cc1ccc(-c2nc(N3CCOCC3)c3cnn(C4CCN(Cc5ccccc5)CC4)c3n2)cc1 +Nc1nc(NC(=O)CCC2CCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CCc1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc(CC)n1 +CC1CCC2C(C)(C)C(O)CCC2(C)C1C=Cc1ccc(-c2cccc(F)c2)cn1 +Cc1cc(C(NC(=O)C(N)C(C)c2ccc(-c3ccccc3)cc2)c2ccc(Cl)cc2)ccn1 +Cc1ncc(-c2cc(C)n(C)c(=O)c2)c(OCC2CC2c2ccc3ccccc3n2)n1 +Cc1nn(C2CCCCC2)c2sc(C(=O)NC3CC3CO)cc12 +OCCCNc1nccc(N2CCN(c3ccnc4cc(Cl)ccc34)CC2)n1 +CN1c2cc3c(cc2C2(C)CCCCC12)c(C(F)(F)F)cc(=O)n3C +CC(C)CC(NC(c1ccc(-c2ccccc2)cc1)C(F)(F)F)C(=O)NCC#N +CCCC1(C)CC(=O)N(Cc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)C(=CC(=O)OCC)C1 +COc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1OC +CN(C)c1ncc(Cc2cn(CC(=O)N3CCN(c4ccc(Cl)cc4)CC3)c(SCc3ccc(F)cc3)nc2=O)cn1 +CCCC(C(CC(C)C)C(=O)NC(CCCN=C(N)NS(C)(=O)=O)C(=O)Nc1nccs1)N(O)C=O +CN(C)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1 +O=C(O)c1cc(-c2cccc(COc3ccc4c(=O)n(C5CC5)sc4c3)c2)ccc1Cl +COc1cc(C#N)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC(NCc1ccoc1)c1ccccc1 +COC(=O)N1CCc2c(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)n[nH]c2C1 +CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)cc2OC2COC2)c1 +CC(Nc1cc(-c2[nH]c(SCc3ccccc3)nc2-c2ccc(F)cc2)ccn1)c1ccccc1 +CC(=NNC(=O)Cn1c(=O)c(Cc2ccccc2)nc2ccccc21)c1ccc(O)cc1 +COC1(c2cc(F)cc(OCc3ccc4c(c3)sc(=O)n4C)c2)CCOCC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(C(F)(F)F)ccc3F)C2)cc1 +CC(O)(c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)c1nccs1 +O=C(NCCCCCCS)c1cc(-c2ccc(F)cc2)nn1CCCO +CCCCC(NC(=O)OCC1(CC)CCCCC1)C(=O)C(=O)NC(C)c1ccccc1 +COCC1CC(O)CN1Cc1cn(-c2ccnc(Nc3ccc4c(c3)c(Cl)c(C)n4C)n2)nc1C +CCN1C(=O)c2c(nc(C#N)n2Cc2ccc(OC)cc2)N2C1=NC1CCCC12 +CC(C)NCCCCN(CC1Cc2ccccc2CN1)C1CCCc2cccnc21 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cccc(-n2cccn2)c1 +CCCCCCCCCCCCCCCCCCOC(=O)N1CCN(C(=O)c2ccc(Cc3noc(=O)[nH]3)cc2)CC1 +CN1CCc2c(sc3c2c(=O)n(-c2ccccc2)c2nnc(SCc4ccccc4)n32)C1 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+O=C(C=Cc1ccc(Br)cc1)Nc1cc(-c2ccc(Br)cc2)[nH]n1 +Cc1sccc1C(=O)NC1C(CC=CCCCC(=O)O)CC2CC1C2(C)C +COC(=O)c1nn(C(=O)c2cccc(OC)c2)c2ccc([N+](=O)[O-])cc12 +CNCC(CC1CCCCC1)NC(=O)N1CCCC(C(O)(CCCNC(=O)C2CC2)c2cccc(Cl)c2)C1 +CC(=O)N1CCC(n2cc(-c3ccn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CC1 +O=C(O)CCc1csc(NC(=O)c2cc3c(n(CC4CCCCC4)c2=O)CCCCCC3)n1 +Nc1cc(Cn2c(C3=NS(=O)(=O)c4ccccc4N3)c(-c3ccc[nH]c3=O)c3cc(Cl)ccc32)ccn1 +NCCn1nc2c3ccccc3sc3c(NCCNCCO)ccc1c32 +O=C(CSC(c1ccc(Br)cc1)c1ccc(Br)cc1)NCCCc1ccccc1 +CN1CC=C(c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)CC1 +COc1ccccc1CCN1Cc2cccc(C(=O)Nc3cccc(-c4nc5ccccc5[nH]4)c3)c2C1=O +CC(C)C(NC(=O)C(CO)NC(=O)NCCCCNC(=N)N)C(=O)NC1CCCN(C(=N)N)C1O +O=C(Nc1ccc2c(c1)C(=O)N(CCC1CCN(Cc3ccccc3)CC1)C2=O)c1ccccc1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(N3CCC(CO)CC3)cc(-c3ccccc3)n2)CC1 +CCCC(Oc1cc(C)c(-n2cc(C3CC3)cn2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 +NC(=O)c1ccc(-n2c3c(c4ccccc42)C(=O)CCC3)cc1NCC1CC1 +COc1cc(Cl)cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncc(F)cn5)ccc43)cc2F)c1 +CCCCCNC(=O)C(F)(F)C(=O)C(Cc1ccccc1)NC(=O)Cn1c(-c2cccc(C)c2)ncc(N)c1=O +O=C(c1cccc(CN2CCN(C3COc4ccccc4O3)CC2)c1)N1CCCCC1 +CC(C)(CCc1ccc2c(c1)OCO2)NCC(O)c1ccc(O)c(C(N)=O)c1 +Cc1sc(C)c(C(=O)NC(C)c2ccc(C(=O)O)cc2)c1Cc1ccc(C(F)(F)F)cc1 +O=C1CN(C(=O)NC(CO)c2ccc(OC(F)(F)F)cc2)c2ncccc2N1 +Cc1cnc(NC(=O)c2cc(Oc3ccc(C(=O)N(C)C)cc3)c3cc(C)oc3c2)cn1 +O=C(OC1CCCN(Cc2ccc(F)cc2)C1)C(O)(c1ccccc1)c1ccccc1 +O=C(Nc1cc2c3ccccc3ccc2c2ccccc12)C(Cl)Cl +CCc1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)oc2ccc(F)cc12 +CN(C)CCNC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2 +CCC#CCOc1nc2oc(=O)cc(CCCC3CC3)c2c(=O)[nH]1 +O=C1NCCc2c1ccc1[nH]cc(CCNC(=O)N3CCCNC(F)(F)C3)c21 +O=C(O)Cc1cnc(C(=O)c2ccc(C(=O)Nc3ccc(Cl)c(Cl)c3)cc2)c2ccccc12 +CCCCCCCCN(C)C(=O)Cn1cc(Cc2cnc(=O)n(CCO)c2)c(=O)nc1SCc1ccc(F)cc1 +O=C(NCc1ccc([N+](=O)[O-])cc1)C(=O)c1c[nH]c2ccc([N+](=O)[O-])cc12 +Cc1cnc2c(NCCN)nc3cc(-c4cn[nH]c4)sc3n12 +CC(=O)Nc1cccc2c1C(=O)c1c(C(C)(C)C)n[nH]c1-2 +CC(=O)Oc1ccc2c(c1)C(C)=CC(C)(C)N2Cc1cccc(C)c1 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+O=C(O)C(CCCCCCCc1ccc2c(n1)NCCC2)NS(=O)(=O)c1ccccc1 +CCn1cc(C(=O)c2cc(OC)c(OC)c(OC)c2)c2ccc(OC)cc21 +CC1=CC(=O)N(Nc2nc(-c3cccs3)nc3sc(-c4cccc(O)c4)c(C)c23)C1=O +CC(C)CN(CC(C)C)c1ccc(C(CC(=O)O)C(F)(F)F)cc1NC(=O)Nc1ccc(F)cc1F +Cc1nccc2cc(NC(=O)NCC(=O)N3CCCC3)ccc12 +CCCn1c(=O)ccc2c(-c3cnc(-c4ccc(CO)nc4)s3)n[nH]c21 +O=C(O)C(Cc1ccccc1)N(Cc1cccc([N+](=O)[O-])c1)C(=O)c1ccc(Cl)cc1Cl +COc1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CC1CCCN1CCN1CCc2cc(-c3ccc(F)cc3)ccc2C1=O +CCC(C#Cc1cc(-c2ccc(C)cc2)n(-c2ccc(OC)cc2)n1)N(O)C(C)=O +O=C(Oc1ccccc1)c1cc2cc(CCl)ccc2oc1=O +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCCCN(C)CCCNc4c5c(nc6ccccc46)CCCC5)c3C(C1)C2 +Cc1cc(OCC(O)CN2CCN(c3ccc(Cc4ccc(F)cc4)cc3)CC2)c(C)c(C)c1N +O=C(NCCO)c1cccc(-c2cccc3cn(Cc4cccc(C(F)(F)F)c4)nc23)c1 +O=C(C=Cc1cccc2cc[nH]c12)CC(=O)C=Cc1cccc2cc[nH]c12 +COc1ccc(-c2ocnc2C(=O)Nc2cnn(CCn3ccc4cc(OC)c(OC)cc43)c2)cc1 +CCCn1c(=O)c2nc(C3CCCC3)[nH]c2n(CCCOC(=O)c2cccc(S(=O)(=O)F)c2)c1=O +CCOC(=O)C1=C(C)NC(=Cc2cc(C)n(-c3ccc(CN(C)C)cc3)c2C)C1=O +O=C(Nc1nc2c(Cl)cccc2s1)NC1CCCCC1CN1CCCC(Cc2ccc(F)cc2)C1 +CC(C)c1nc2c(Cl)cccn2c1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1 +COc1cccc(-c2ccc3cccc(C(=O)NCCN(C)C)c3n2)c1 +CCc1c(Sc2ccccc2)n(OC(C)C)c(=S)[nH]c1=O +O=P(O)(O)OC1C(CO)OC(OC2C(CO)OC(OCCCc3ccccc3)C2OP(=O)(O)O)C(O)C1OP(=O)(O)O +CCNC(=O)NCCC(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1 +Cc1cc(C(=O)Nc2cc(Cl)cc(N3CCCCC3)c2)cc(C)c1OCCN +Nc1ncc(-c2cc(N3CC4CC(C3)N4C3COC3)nc(C3CC3)n2)cc1OC(F)F +CONC(=O)c1ccc(C)c(Nc2ncnn3cc(C(=O)OC)cc23)c1 +Cc1cc(F)ccc1CNc1ccc(-c2nc3c(cc2Cl)OCCO3)cn1 +Cc1cc(CN(C)C)ccc1C(=O)Cn1ncc(OCc2ccc(Br)cn2)cc1=O +COc1ccc(Cn2c(CCC3C=Nc4ccccc43)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 +COCCNC(=O)c1ccc(Nc2cc3cc(-c4cnn(CC(C)(C)O)c4)ccc3cn2)c(OC)c1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(C2CC2)c1C +CC[N+](C)(CC)CCOC(=O)C(O)(c1ccccc1)c1ccccc1 +Cc1cn(C2C=CC(COP3(=O)OCc4cc5ccccc5cc4O3)O2)c(=O)[nH]c1=O +CCN1c2ncccc2C(=O)Nc2c(C)cc(NCCO)nc21 +Cn1ncnc1COc1cccc(-c2cnnc(-c3ccccc3)c2)c1 +COc1ccccc1CNCCn1c(=O)c2ccc3c(=O)n(CCNCc4ccccc4OC)c(=O)c4ccc(c1=O)c2c34 +CC(C)(O)c1cncc(-n2nc(C(F)(F)F)c3ccccc32)c1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc4cc(OCC(=O)O)ccc4n3)C12 +CCCN(CCCNc1ccnc2cc(Cl)ccc12)Cc1ccco1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1ccc(F)cc1F +Cc1ccccc1C(=O)NCCNC(=O)c1ccc(-c2cccc3[nH]nc(N)c23)cc1 +C#CC(C)n1[nH]c(=O)c2[nH]c3cc(Cl)ccc3c(=O)c2c1=O +N#CCNC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +N#Cc1c2n(c3c(N4CCN(CCc5ccccc5Cl)CC4)ncnc13)CCCC2 +COC(=O)c1csc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3ccccc3[nH]2)o1 +CC#CCn1c(N2CCCC(N)C2)nc2c1C(=O)N(Cc1nc(C)c3ccccc3n1)C1=NCCCN12 +Cc1ccn2c(=O)n(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)nc2c1 +Cc1nn(Cc2ccc(NC(=O)c3cc4cc(Cl)ccc4o3)cc2)c(C)c1CC(=O)O +OC1CCC(Nc2ncc(Cl)c(NC34CC5CC(CC(O)(C5)C3)C4)n2)CC1 +Nc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 +CC(=O)N1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cc(-n2nccn2)ccc1F +CCc1cc(NC(=O)NC(C)C(O)CN2CCCC(Cc3ccc(F)cc3)C2)cc(-c2nnnn2C)c1 +COc1ccc(-c2nsc(C)c2C(=O)N=C(N)NCc2cc(Cl)c(NC(=O)CN3CCC3)c(Cl)c2)cc1 +O=C(c1ccc(F)cc1)C1CCN(CC(=O)N(Cc2ccccc2)Cc2nc3c(c(=O)[nH]2)COCC3)CC1 +CN1c2ccc(-c3cncc(Cl)c3N3CCC4(CCCN4CCCS(C)(=O)=O)CC3)cc2CS1(=O)=O +O=C(NC1CC(O)C1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +O=C(Nc1ccc(B(O)O)cc1)c1ccc(C=C2SC(=O)N(Cc3ccc(F)cc3)C2=O)cc1 +O=C(NCc1cc(Cl)cc(Cl)c1)C1CCCC1C(O)CCc1cccc(OC(F)(F)F)c1 +O=C(NC1CCOCC1O)c1cn(Cc2ccc(-n3cccn3)cc2)c2cccnc12 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)cc1-c1ccc(F)cc1 +COC(=O)N1CCC(Sc2cccc(C(CC#N)Nc3nc4nc(C)ccc4[nH]3)c2)CC1 +CCOC(=O)C1(Cc2ccccc2)CCc2cnc3c(-c4ccc(Cl)cc4)cnn3c21 +O=C(O)C12CC3CC(C1)C(NC(=O)C1(N4CCN(c5ccc(C(F)(F)F)cn5)CC4)CCC1)C(C3)C2 +CN1CCC(O)(C#Cc2ccc3c(c2)-n2nc(C(N)=O)cc2C2(COC2)CO3)C1=O +N#Cc1cc(C(=O)NC(CO)c2ccccc2)ccc1-c1cn[nH]c1 +O=c1cc(-c2ccc(F)c(F)c2)oc2c1ccc1ccccc12 +O=S(=O)(NCCN1CCc2ccccc2C1)c1ccc2ccccc2c1 +COc1nc(N2CC(OC)C2)nc(OC)c1NC(=O)CC(C)(C)C +COC(=O)C1C2CC3CCC1N3CC2=Cc1ccc(I)s1 +CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccccc4)c3)cc21 +CCCc1c(-c2ccccc2)nc2ccccc2c1C(=O)NC(CC)c1ccccc1 +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2cccs2)sc2cc(O)ccc12 +O=C(O)CN1C(=O)C(NC(=O)C(S)Cc2ccccc2)CCCC12CC2 +Cc1ccc(N2CCN(Cc3ccc4ccc(=O)oc4c3)CC2)cc1 +O=C(OC1CCCC1)c1cc2c3ccccc3nc-2c[nH]1 +CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCCC)nc3ccc(NC(=O)NCC)cc3c2=O)cc1 +CCCCCCC(CC)C(CO)NS(=O)(=O)c1ccc(Cl)s1 +Cc1cc(-c2ccc(C(N)=O)cc2C)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c2n1 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3cccc(S(=O)(=O)N4CCN(C)CC4)c3)nc12 +CCOCCC1(Oc2ccc(Oc3ccc(-c4cnco4)cc3)cc2)C(=O)NC(=O)C(N)C1=O +CNS(=O)(=O)NC(=O)c1cnc(OCC23CC4CC(CC(C4)C2)C3)c(C2CC2)c1 +Cc1ccccc1C1CC(NC(=O)Nc2cccc(F)c2)C(=O)N(CC(=O)NC(C)(C)C)C(c2ccccc2)C1 +COc1ccc(CN(C)C)c(Oc2ccc(Cl)c(Cl)c2)c1 +Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)c5csc(C)n5)c4)CC3)cccc2n1 +CC(=O)Nc1sc2c(c1Cc1nnc(SCC(=O)NNC(=O)CCl)n1NC(C)=O)CCCC2 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCC(CCO)CC4)nc3n2)cc1CO +O=C(Nc1ccncc1)c1cc(N(CC2CC2)C2CCCCC2)ncn1 +COc1ccc2c(c1)S(=O)(=O)Cc1c(C(=O)N3CCOCC3)nn(C)c1-2 +CCCC1(O)CCC2(C)C(CCC3C4CCC(=O)C4(C)CCC32)C1 +COc1ccc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c2cc(C(F)(F)F)nn12 +CC1CN(CCC(=O)N(c2ccccc2)C(Cc2ccccc2)C(=O)O)CCC1(C)c1cccc(O)c1 +O=C(Nc1cc2cc[nH]c(=O)c2cc1Cl)C1CNCCC1c1ccccc1 +O=c1c(=Cc2ccco2)sc2nc3cc(Br)cnc3n12 +CCC(CC(C)C)NC(=O)C1CNCC(N2CC(=O)N(c3ccccc3Cl)CC2(C)C)C1 +CC(C)CN(Cc1ccc(NC2CCN(S(C)(=O)=O)CC2)cc1)S(=O)(=O)Cc1ccccc1 +Nc1ncc(C2CCOCC2)cc1-c1ccc(C(=O)NC(CO)c2ccccc2)cc1Cl +O=C(Nc1cccc2c1OC(c1nnn[nH]1)CO2)c1ccc(OCCCCc2ccccc2)cc1 +COc1cccc(CNC(=O)n2sc3ncccc3c2=O)c1 +O=[N+]([O-])c1cn2c(n1)OC(COc1ccc(-c3ccc(F)cc3)nn1)CC2 +Cc1c(C(O)CN2CCC3(CC2)CCN(C2=C(C4CC4)C(=O)OC2)C3=O)ccc2c1COC2=O +CC12CCC3C(C(Cc4ccc(N)cc4)=CC4=CC(=O)CCC43C)C1CCC2=O +c1ccc(Cn2c(SCc3ccncc3)nnc2-c2cccs2)cc1 +COc1ccc(C(=O)C=Cc2ccc(OC)c(OP(=O)(O)O)c2)cc1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)cc1C(=O)NCc1ccncn1 +O=C(OCCOc1cccnc1)C1CCCCN1S(=O)(=O)Cc1ccccc1 +c1ccc(-c2noc(COc3ccc(C4CCNCC4OCc4ccc5ccccc5c4)cc3)n2)cc1 +N#Cc1ccc(-c2cnc(N)c(-c3ccc(C(N)=O)cc3)n2)cc1 +O=C(c1ccc(F)cc1)N1CCN2C(=O)c3ccccc3C12c1ccc(Cl)cc1 +Cc1cc(OCc2cccc(-c3c(C)cccc3C)c2)ccc1CCC(=O)O +CN1OC2(N=C1N)c1cc(-c3cc(Cl)cc(C#N)c3)ccc1CC21CCc2ccccc2CC1 +CC1Cc2ccccc2N1C(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1 +NC(=O)c1cccc2[nH]c(-c3ccc(C4CCCN4)cc3F)nc12 +CC(=O)N(C)c1ccc2ccn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 +CN1CC=C(c2cc(C(F)(F)F)ccc2N2CCOc3cc(S(=O)(=O)Nc4ncns4)ccc32)CC1 +COCCOCCOCCOCCOC(=O)OC[n+]1ccc(NC(=NCCCCCCOc2ccc(Cl)cc2)NC#N)cc1 +Cc1ccc(NC(=O)NS(=O)(=O)c2ccc(OCCCN3CCCCC3)cc2)cc1 +COc1ccc2[nH]c3c([N+](=O)[O-])cc4cn[nH]c4c3c2c1 +COc1ccc(CN2CCN(CCCC(=O)NC3c4ccccc4SCC4CCCCC43)CC2)cc1 +Cc1ccc2c(N3CCN(CCc4ccc5c(c4)OCC(=O)N5)CC3)cccc2n1 +CN(C1CCN2CCc3ccccc3C2C1)S(=O)(=O)CC(C)(C)C +c1ccc(-c2csc(Nc3nc(N4CCOCC4)nc(N4CCOCC4)n3)n2)cc1 +N#Cc1ncc2nc1OCCCCCOc1cc(NCc3ccncc3)c(Cl)cc1NC(=O)N2 +CC(=O)N1CCN(c2cnc3cccc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +c1ccc(CNCC2CCN(CCc3c[nH]c4ccc(-n5cnnc5)cc34)C2)cc1 +O=C(c1cccnc1)N1CC2C(CNc3nc(-c4ccccn4)cs3)C2C1 +COc1cccc(C(C)Nc2cc(-c3cccc(C)c3)nc(C)n2)c1 +CCCCCc1cc(O)c2c(c1)OC(C)(C)C1CC(O)C(C)=CC21 +O=C(Nc1nnc(-c2ccc(Cl)cc2)s1)c1ccccc1F +COCCc1sc(S(=O)(=O)NC(=O)Nc2ncc(SC)s2)cc1C +Cc1nccc2c1[nH]c1cc(OCc3ccccc3)ccc12 +CNC(C)C(=O)NC(C(=O)NC(CCCNC(=O)OCc1ccccc1)C(=O)NC1CCCc2ccccc21)C(C)C +O=C(CCc1ccccc1)c1ccc2nc3c(cc2c1)CCCO3 +COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)C3CCOCC3)CC1)C(=O)C2 +Cn1cc(-c2cnc3nc(OCc4ccc(Oc5ccc(Cl)c(C(F)(F)F)c5)cc4)ccn23)cn1 +Cn1cc(-c2cn(-c3ccnc4c3c(C(F)(F)F)nn4-c3ccc(C(N)=O)cc3Br)cn2)cn1 +NC(CC1CCCCC1)P(=O)(O)CC(=Cc1ccc(Br)cc1)C(=O)O +O=C(C=CCN1CCCOCC1)N1CCc2c(sc3ncnc(Nc4ccc(F)c(Cl)c4)c23)C1 +CCCCNC(=O)C1CCN(C(=O)CCC(=O)N(CC(C)(C)C)c2ccc(Cl)cc2C(O)c2ccccc2Cl)CC1 +O=C(Cc1c(-c2ccccc2)[nH]c2ccccc12)N1CCCC1 +Cn1cc2c(OCC(=O)NCC(O)CN3CCc4ccccc4C3)cccc2n1 +O=C(NO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1ccc(Cl)cc1 +CCCCCCCCCCCCCCCCNCCOc1ccc(C(=O)c2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cc1 +NC1CCC(Nc2nc(NCc3ccc(-c4cccs4)nc3)c3ncn(C4CCCC4)c3n2)CC1 +CN(C1(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)CC1)S(=O)(=O)c1ccccc1F 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+O=C(CCC(=O)N1CCCC1)c1ccc2[nH]c3c4c(c5c(c3c2c1)C(=O)NC5=O)CCC4 +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(OCc2cn(Cc3ccc(Cl)cc3Cl)nn2)c1 +CN(C)S(=O)(=O)NC(=O)CCCc1c(-c2ccc(F)cc2)[nH]c2ccc(C#N)cc12 +CN1CCN(Cc2ccc(C(=O)Nc3sc(-c4ccnc(C#N)c4)nc3C(N)=O)cc2)CC1 +O=C(O)C(Cc1ccccc1)N1C(=O)C(=CC=Cc2ccco2)SC1=S +CN(CCCN1CCN(CCNc2c3c(nc4ccccc24)CCCC3)CC1)c1ccccc1 +CC1CN(c2cccc(C#N)c2)CCN1c1nc(-c2ccncn2)cc(=O)n1C +COc1ccc(-c2cc3ncccc3c(OCC3CNC(=O)N3C)n2)cc1OC +Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cc[nH]n1 +N#Cc1c(F)cccc1-c1cc(-c2cnc3nc(C(F)(F)F)ccn23)ccc1F +CCCNS(=O)(=O)c1ccc(-c2ccc(CCN3CCCC3C)cc2)cc1 +CCOc1ncccc1-c1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +O=C(Nc1ccc(-n2cccc2)cc1)C(=O)c1c[nH]c2cc(Cl)ccc12 +COc1nc(-c2ccnc(NC(=O)C3CC3)c2)ncc1C(N)=O +COc1cc2c(NC3=CC(=O)C(OCc4ccccn4)=CC3=O)ncnc2cc1OCCCN1CCCC1 +COC(=O)C1C(c2cccc(-c3ccco3)c2)CC2CCC1N2C +CC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)Cc1cccc2ccccc12)C(=O)NC(C=O)Cc1ccc(O)cc1 +COCC(COc1ccc(OCc2cccc(C(F)(F)F)c2)cc1C(C)=O)C(=O)OC 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+O=C(c1ccn(-c2cc(F)c(O)c(F)c2)c1)c1ccc(Br)cc1F +COCCOCC(=O)N1CCC(c2nc(-c3ccc([S+](C)[O-])cc3)c(Sc3ccc(Cl)cn3)o2)CC1 +CC(C)n1c(=O)c(C(=O)NC2CC3CCC(C2)N3CCS(=O)(=O)O)cc2ccccc21 +O=c1[nH]nc2[nH]c(CNCc3ccc(Cl)c(Cl)c3)nc3cccc1c32 +[H]C([H])(c1ccccc1)N1CC(C)N(C(=O)NCc2ccccc2)C(C)c2ccncc21 +Oc1nc2ccccc2n1C1CCN(Cc2ccc(-c3nc4ccccc4cc3-c3ccccc3)cc2)CC1 +COc1cnc(C(N)=O)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(C)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 +Cc1cn(Cc2ccc(Cl)cc2Cl)c2c(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 +CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CSC(=S)N(CC)CC +O=S(=O)(CCCF)NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2 +CNCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(OC)cc2)c1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(C=O)C(C)C +CCOC(Cc1cccc(C2=NOC(c3ccccc3)C2)c1)C(=O)O +Cn1cc(S(=O)(=O)NC2CCN(CCOc3ccccc3-c3ccccc3)CC2)cn1 +COCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2noc(C)n2)cc1 +CN(C(=O)C(Cc1ccc2ccccc2c1)N(C)C(=O)c1cccc(CN)c1)C(CO)Cc1ccccc1 +CCCCCCCc1cc(=O)c2cc([N+](=O)[O-])ccc2[nH]1 +COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2CCO +O=C(c1ccc(-c2ccccc2C(F)(F)F)nc1)N(Cc1ccccc1)CC1CCCO1 +CC1(C)CC1C(=O)NC(=CCCCCCNC(C)(C)P(=O)(O)O)C(=O)O +CS(=O)(=O)N1CCC(n2cnc3cnc4[nH]ccc4c32)CC1 +CC1CN(c2sc(C3CC3)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21 +NCCn1cc(NC(=O)c2c(N)nn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1 +Cn1cnc(S(=O)(=O)N(CCN(Cc2cncn2C)c2ccc(C#N)cc2)Cc2cccc(C#N)c2)c1 +O=S(=O)(NCc1ccc(F)cc1)c1ccc2c(c1)nc(SCCNCc1ccccc1)n2Cc1ccccc1 +CCOC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(Cl)c2)nc1C +Clc1ccc(-c2n[nH]cc2-c2ccnc(NC3CC3)n2)cc1 +CNNC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1C +CC(C)n1nc(-c2ccc(O)cc2)c2c(N)ncnc21 +Fc1cccc(-c2cc(N(CCCN3CCCCCC3)Cc3ccc4c(c3)OCO4)on2)c1 +Cc1nc(NCc2nccs2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CCC(=O)NC1CCc2c(-c3ccc(C(F)(F)F)c(F)c3)cncc21 +COc1ccccc1C(=O)NCCSC1c2ccccc2COc2ccc(C(=O)O)cc21 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCN(Cc2cccc3cc[nH]c23)C1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(N3CCCCC3=O)c2)CCCCC1 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+CCOC(=O)Cc1cc(-c2ccc(F)cc2)n(-c2ccc(S(C)(=O)=O)cc2)c1C +COC(=O)C(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 +[C-]#[N+]c1ccc(CCN2CCN(C(=O)Cc3ccc(-n4cnnn4)cc3)CC2)cc1F +COc1ccc(C(O)(c2ccc3nc(OC)c(Cc4ccc(-n5cccn5)cc4)c(Cl)c3c2)c2cncs2)cn1 +NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccn(C(F)F)c(=O)c2)cc1 +O=S(=O)(NCCc1c[nH]cn1)c1ccc2ccccc2c1 +COc1ccc(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)C(CSc2ccc(C)cc2)C(=O)NO)cc1 +CNC(=O)C(c1ccccc1)N1CCn2c(C3CC3)nc(Cl)c2C1CCc1ccc(C(F)(F)F)cc1 +C=CCNc1ccc2c(c1)C(=O)c1ccc(C3=NCCN3)cc1S2(=O)=O +Cc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(C=Cc3ccccn3)cc2)cc1 +c1coc(CNc2ncccc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c1 +O=C1NCCN1CCN1CCC(n2cc(-c3ccc(F)cc3)c3cc(F)ccc32)CC1 +O=C(c1cccs1)N1CCCC(c2nnn(-c3cccc(Cl)c3)n2)C1 +O=C1NCCc2c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[nH]c3cccc1c23 +CCC(NC(=O)c1ccc2c(c1)c(SC)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 +CCSCC1CC(O)(c2ccccc2)C(c2ccccc2)C(c2ccc(Cl)cc2)O1 +O=C(O)c1ccc(Cn2cnc3cnc(C(=O)NCc4ccc(C(F)(F)F)cc4)cc3c2=O)cc1 +COc1cc2c(Nc3nc4ccccc4s3)c(C#N)cnc2cc1OCCN1CCN(C)CC1 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+COc1cc(-c2nc(C3CCC3)n3ccnc(N)c23)ccc1Oc1cccc(C)c1 +CC1CN(c2n[nH]c3cc(NC(=O)NC(c4ccc(F)cc4)C(C)(C)O)ncc23)CC(C)O1 +CN(C)Cc1ccn2c(-c3ccnc(NCc4ccc(Cl)cc4)n3)c(-c3ccc(F)cc3)nc2c1 +CN(c1ccc(NC(=O)C2CCCCC2)cc1OCc1ccccc1)S(C)(=O)=O +COc1ccc(-c2cc3ccccc3nc2C=CC(=O)c2ccc(F)cc2)cc1 +COCC1CNC(C)CN1CC(=O)N1CC(C)(C)c2cc(F)c(S(=O)(=O)c3ccccc3)cc21 +O=C(NS(=O)(=O)c1ccc(Br)c(Br)c1)c1ccc(Cl)cc1Cl +Nc1cc(C(=O)O)ccc1Cn1cc(-c2ccc(-c3ccccc3COc3cc(C(F)(F)F)ccc3Cl)cc2)nn1 +Cc1ccc(-c2ncccn2)c(C(=O)N2CCCC(Nc3ccc(C(F)(F)F)cn3)C2C)n1 +Cc1ccn(CC(=O)N2CCN(c3scnc3-c3nc4ccccc4[nH]3)CC2)n1 +CN1CCc2c(cccc2Nc2cnn(C)c(=O)c2Cl)C1 +COc1ccc(-c2c(F)c(C(=O)NN3CCCCC3)nn2-c2ccccc2Cl)cc1 +CCc1cn(Cc2c(C)cccc2C)c2cc(C(=O)O)ccc12 +CC(=O)N1CCN(c2ccc(CN(C(C)(C)C)S(=O)(=O)Cc3ccccc3)cc2)CC1 +O=C1N=C(N2CCCCC2)SC1=Cc1ccc(N2CCC(NCC(O)COc3ccccc3)CC2)cc1 +CC(=O)CCCC(=O)NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCCc2ccc3ccccc3c2)C1=O +CC(=NNC(N)=S)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 +CC(CF)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 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+O=C(NC(Cc1ccccc1)C(O)CN(OC1CCCCC1)S(=O)(=O)c1ccc2c(c1)OCO2)OC1COC2OCCC12 +O=C(Nc1ccc(N(CCCl)CCCl)cc1)Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1 +Oc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1CN1CCCC1 +COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(Cl)c2-c2ccccc2)nc1 +CCC(C)NC(=O)c1nn(-c2ccc(Cl)cc2)c(=O)c2ccccc12 +O=C1C(Cl)C(c2ccc([N+](=O)[O-])cc2)N1Nc1ccnc2cc(Cl)ccc12 +Cc1cccc2cc(C(=O)NC3CCN(C(C)C)CC3)n(CC(=O)Nc3ccc(Cl)cc3)c12 +CCCc1c(C(=O)Nc2cc(S(C)(=O)=O)ccc2C)cnn1-c1ccccc1 +CS(=O)(=O)c1cccc(Oc2cccc(-c3ccnc4c(Cl)cccc34)c2)c1 +CC(=O)NC(CNC(=O)c1cc2n(n1)CCN(CCC1CCNCC1)C2=O)C(=O)O +Cc1cccc(-c2cccc(NCc3cncn3Cc3ccccc3)c2)c1 +O=C(Nc1ccc(C2=NCCN2)cc1)c1ccc(C(=O)Nc2ccc(C3=NCCN3)cc2)cc1 +CC(C)(C)c1ccc(-c2ccc(-c3nc4cc(C=C5SC(=S)NC5=O)ccc4[nH]3)o2)cc1 +CN(C)CCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1 +O=C(C1CC(N2CCN(c3cnccn3)CC2)CN1)N1CCC(F)(F)C1 +O=C(Cc1ccccc1B(O)O)N1CCC(Oc2ccc(C(F)(F)F)nc2)CC1 +Cc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CCN)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1 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+CCOC(=O)c1ccc(N2CCC(OC(=O)N3CCN(C(C)C)CC3)CC2)nc1 +CCn1c(NC(C)C)nc2c(C3CCN(C(=O)c4ccccn4)C3)csc2c1=O +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ncccn2)nc1OCCOC(=O)Nc1ccccn1 +COc1cc(C)cc(OC)c1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 +COc1cc(Cl)ccc1CC(C)C(=O)N1CCN(c2ccc(Cl)cc2C(N)CC(C)C)CC1 +Nc1ccc2c(c1)CC(n1nc(-c3cc(F)c4c(c3)NCCO4)c3c(N)ncnc31)C2 +NS(=O)(=O)c1ccccc1N1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O +Brc1ccc2cc(CCc3cc4ccc(Br)cc4[nH]3)[nH]c2c1 +O=C(NCCCN1CCCC1=O)C1CC1c1ccc(Sc2ccccc2N2CCCC2)c(C(F)(F)F)c1 +Cc1ccc(-c2ncc(C(=O)c3ccc(F)cc3)n2S(=O)(=O)c2ccccc2)cc1 +CNC(=O)c1ccc(C)c(Nc2ncnc3c2cnn3-c2ccc(F)cc2)c1 +Cc1ccsc1C(=O)NC1CCC(CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1 +Cc1cnc(-c2cc(N3CCn4cc(C(=O)Nc5cccnc5)nc4C3)ncc2Cl)c(C)c1 +O=C1NC(C(=O)O)Cc2cn(nn2)CCCCOc2ccc(Cl)c1c2 +CCCn1c(=O)c2nc(-c3cnn(Cc4noc(-c5ccc(C(F)(F)F)cc5)n4)c3)[nH]c2n(CCC)c1=O +CCCc1cc(-c2nc(OCC)cs2)ccc1OCCCOc1ccc2c(c1)CCC2CC(=O)O +COc1ccc(-c2c(SCc3ccncc3)oc3cc(O)ccc3c2=O)cc1 +CC(C)N1CCC(NC(=O)c2cc3c(Cl)cccc3n2Cc2cc(-c3ccc(Cl)s3)on2)CC1 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1n[nH]cc1Nc1ncnc2[nH]ccc12 +Cc1cc2c(s1)Cc1c(C(=O)NN3CCCCCC3)nn(-c3ccc(Cl)cc3Cl)c1-2 +Cc1cccc(C)c1Oc1c(C(=O)N2CCNCC2)c2ncc(O)cc2n1-c1ccccc1 +CCCCCCCNC(=O)Nc1cc(C=CC(=O)NO)ccc1OCCN(CC)CC +COc1ccccc1CNCCc1ccc(NC(=O)Nc2cnc(C#N)cn2)cc1Cl +CC(C)(C)C(=O)N(CCCCCCN1CC(O)C(O)C(O)C1CO)C1CCCCC1 +O=C(Nc1ccc(Br)cc1)NC(c1ccc(Br)cc1)c1ccc(Br)cc1 +Cc1ncc(Cl)cc1C(=O)NC1CCC(Cn2nc(-c3cccnc3)cc2C)CC1 +COc1ccc(Nc2nccc3ccn(S(=O)(=O)c4ccc(OC)cc4)c23)cc1 +c1ccc(CN2CCC(c3cc(-c4ccccc4)[nH]n3)CC2)cc1 +CC(C)n1c(=O)c2c(-c3ccc(F)cc3)ncn2c2cccc(Cl)c21 +N#Cc1ccc2c(NC3=NCC4(CN5CCC4CC5)O3)ncnn12 +Cc1ccc(C(=O)Nc2cccc3cc(Oc4cncc(C(N)=O)c4)ccc23)cc1[N+](=O)[O-] +c1ccc(CNc2ccsc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)nc1 +CCOC(=O)N1CC(C(=O)Nc2ccc(Cl)cc2)C(C(=O)Nc2ccc(-n3ccccc3=O)cc2F)C1 +COc1cc(NC(=O)c2cc3nc(C)cc(C)n3n2)c(OC)cc1Cl +CNc1n[nH]c2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 +Cn1nc(C(=O)N2CCN(CC(=O)c3ccc(F)cc3)CC2)cc1-c1ccco1 +Clc1cccc(Nc2nc(-c3ccccc3)nc3ncccc23)c1 +O=C(O)c1ccoc1-c1cccc(NCCNCC(O)c2cccc(Cl)c2)c1 +CCCOc1cc(C#N)cc(OC)c1Oc1nc(Nc2ccc(C#N)cc2)nc2ccccc12 +COC(=O)c1cc(-c2ccc(Cl)c(Cl)c2Cl)[nH]n1 +Cc1ccc(S(=O)(=O)NC(=O)N2CCC(N3CCC(Oc4ccc(Cl)c(Cl)c4)CC3)CC2)cc1 +O=C(O)C1CCN(c2ccc(-c3c(C=Cc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cc2)CC1 +Cc1cc(C)c(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(-c2ccccc2)c1 +CCCOc1cc(C)c2c(c1C)CC(C(C)C(=O)Nc1ncc(C)s1)CC2 +NC(=O)c1ccc(-n2c3c(c4cc(F)ccc42)C(=O)CCC3)cc1NC1CC1 +COc1ccc(C2=NC(=O)C(=Cc3cc(OC)c(OC)c(OC)c3)O2)cc1 +CC1CN(Cc2ccc(NS(=O)(=O)c3ccc(-c4ccc(F)cc4)nc3)cc2C(F)(F)F)CCN1 +O=S(=O)(c1ccccc1)c1cc(OC(F)(F)F)c2oc3c(c2c1)CNCC3 +COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(NC(=O)Cc2ccccn2)c2c[nH]c3ccccc23)cc1 +O=C1OC2(CN3CCC2CC3)CN1c1ccc2ccccc2n1 +COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NC2CCC2)cc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1Cl +c1ccc(CCNc2ncnc3nc(-c4ccc(N5CCOCC5)nc4)cnc23)cc1 +CC(C)(CO)CNC(=O)c1cc2cc(C#N)ccc2n1Cc1cc(Cl)cc(Cl)c1 +CCCS(=O)(=O)Nc1ccc(F)c(-c2cc3cncc(Br)c3cn2)c1F +O=C(CCCN1C2CCC1c1c([nH]c3ccccc13)C2)c1ccc(F)cc1 +CC(C)CC(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C2CCOC2c2ccc(Cl)cc2)CC1 +OCC(Nc1cncc2nnc(-c3ccc(OC(F)F)cc3)n12)c1ccc(F)c(F)c1 +COC(=O)c1cccc(Nc2nc(-c3cccnc3)nc3ccccc23)c1 +Cn1ncc2cc(Cc3n[nH]c4ccc(C(=O)N5CCC(F)(F)C5)cc34)ccc21 +Cc1ccccc1COCC(C#N)NC(=O)C(CC(C)(C)C)NC(=O)N1CCOCC1 +CCCCC12CCC(=O)C(C)=C1c1ccc(O)cc1C2 +COC(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)(c1ccc(F)cc1C)c1ccc(F)cc1C +COc1ccc2[nH]cc(CCn3cc(NC(=O)c4ncoc4-c4ccccc4)cn3)c2c1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc([S+]([O-])c3ccccc3)ccc21 +COCCOc1cc2ncnc(Sc3nc(C)c(CC(=O)Nc4cccc(C(F)(F)F)c4)s3)c2cc1OCCOC +NC(=O)c1c(Nc2cc(Cl)c(N3CCNCC3)c(Cl)c2)nc(Cc2c(Cl)cccc2Cl)n2cnnc12 +Cc1ncn(-c2ccc(Nc3nccc(-c4cc[nH]n4)n3)cc2)n1 +CC(C)c1ccc(NC(=O)C=CC(=O)c2cccc3c2CCCC3)cc1 +COc1cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncco5)ccc43)cc2F)ccc1Cl +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2ccc(-c3ccccc3)cc2)cc1 +CC(Oc1cc(-c2ccc3c(c2)ncn3C)cc2ncccc12)C1CNC(=O)C1 +Cc1ccc(C2C(=O)Nc3ccc(-c4cncc(OCC(N)Cc5c[nH]c6ccccc56)c4)cc32)o1 +CC(C)C(NC(=O)Cn1ccc2c(=O)n(-c3ccccc3)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +C#CCNc1ncnc2sc3c(=O)n(-c4ccc5ncsc5c4)cnc3c12 +COc1ccccc1N1CCN(CCCNC(=O)c2ccc[nH]2)CC1 +O=C(O)c1nc2c(O)nc3cc(C(F)(F)F)c(-n4cccc4)cc3n2n1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCCCC2)C1=O)c1ccccc1 +O=C(NS(=O)(=O)c1ccc2ccccc2c1)c1cc2ccccc2n1Cc1cccc(C(F)(F)F)c1 +Cc1cc(C)cc(-c2c(O)nc3cc(Cl)c(C(=O)Nc4ccncn4)cc3c2OCCC2CCCC(C)N2)c1 +CC(C)(CNC(=O)c1cccc(C(F)(F)F)c1)CN(C1=NS(=O)(=O)c2ccccc21)c1ccccc1 +O=C(Nc1cc(-c2ccccc2)ccc1O)c1ccccn1 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCC2CCCOC2c2ccccc2)cc1F +COCC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)cn3)c2)c2cnc(N)nc21 +CC(C)(CCCON=C(c1ccccc1)C(Cc1ccccc1)n1ccnc1)C(=O)O +CC(=O)NC(C)Cc1ccc(C#Cc2cnc(OCc3cccc(F)c3)nc2)cc1 +CN(C)c1ccc(C=Cc2sc3ccccc3[n+]2Cc2ccc3ccccc3c2)cc1 +COc1cccc(CCNC(=O)CC(O)C(COCc2ccc(Br)cc2)NC(=O)c2c(F)cc(F)cc2F)c1 +NCCCn1cc(-c2ccc3ccc4ccc(-c5cn(CCCN)nn5)nc4c3n2)nn1 +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc(C(C)=O)cc4)c3c2)C1 +N#Cc1c2n(c3c(N4CCN(CCc5cccc(Cl)c5)CC4)ncnc13)CCCC2 +CC(C(=O)N(C)O)c1ccc(OCc2ccccc2)cc1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OCc3ncco3)cc2n1Cc1ccccc1 +CN1CCC(CCNCC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)C1 +CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)[nH]c2n1 +O=C1NCc2cccc(c2)CNC(=O)c2coc(n2)-c2csc(n2)-c2cccc(n2)-c2nc(co2)-c2nc1co2 +NC(=O)c1nc(Nc2ccc3cnccc3c2)sc1NC(=O)c1ccsc1 +Cc1ccc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCCC3)nc12 +Cc1nc(N)ncc1CNC(=O)Cn1c(C)ccc(NS(=O)(=O)Cc2cccc3c2OCCO3)c1=O +O=C1NC(NCc2ccccc2)=NC1=Cc1c[nH]c2ncc([N+](=O)[O-])cc12 +c1cc2c(ncn3nnc(C4CCC(CN5CCOCC5)CC4)c23)[nH]1 +CN1CCN(c2ccc(Nc3ncc4c5cc[nH]c(=O)c5n(C5CCCC5)c4n3)nn2)CC1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NS(=O)(=O)c1ccc(C)cc1 +NC1(c2ccc(-c3nc4ccc(-n5cccn5)cn4c3-c3ccccc3)cc2)CCC1 +COc1ccc(C(=O)c2cn(CC3CCCCN3C)c3ccccc23)c2ccccc12 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cnc(C#N)cc1c2C +Cn1ccnc1S(=O)(=O)Nc1cccc(C(c2c(O)cc(C(CC3CC3)CC3CC3)oc2=O)C2CC2)c1 +N=C(c1ccc(C(=O)N2CCN(S(=O)(=O)c3cc4ccc(Cl)cc4s3)CC2)cc1)N1CCCCC1 +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3ccccn3)sc2c1 +COc1cc2nc(Sc3nnc(N)s3)n(-c3ccc(Oc4ccccc4)cc3)c(=O)c2cc1OC +CC1(C)CCC(C)(C)c2cc(C=CC(=O)NCc3ccc(NS(C)(=O)=O)c(F)c3)ccc21 +COc1cccc(CNC(=O)Nc2nc(-c3ccncc3)cs2)c1 +Cc1cncc(-c2cnc(NC3CCNCC3OCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 +CN1C2CCC1CC(NC(=O)c1cccc3[nH]cnc13)C2 +COc1ccc(-c2ccc3ncnc(Oc4cccc(O)c4)c3c2)cc1 +Cc1cc(C)cc(-c2cnc3cc(Cl)c(-c4ccc(Cl)nc4)cc3c2OCCC2CCCCN2)c1 +CC(C)CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1C(=O)N(C)N(C(C)C)C(=O)c2ccccc21 +[N-]=[N+]=Nc1ccc(I)c(-c2cc(Cc3ccncc3)cc3cccnc23)c1 +O=C(Nc1cccc(Oc2ccc3c(C=Cc4c[nH]cn4)n[nH]c3c2)c1)c1ccccc1 +O=C(NCC1CC1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +CCc1cc(CNc2nc(Nc3cc(C4CC4)n[nH]3)cc(N3CCN(C)CC3)n2)on1 +CCCC[S+]([O-])c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N +Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCCc1ccncc1 +O=C(Nc1ccc(-c2cc(N3CC4CCC(C3)O4)c3nccn3n2)cc1)Nc1cccnc1 +O=C(O)c1ccnc2cc(C(OCCCN3CCCCC3)c3ccccc3Cl)[nH]c12 +O=C(O)CCCC(=O)N1CCC2(CC1)CCN(c1ccncc1)CC2 +CCN(CC)CCCNc1cc(-c2cccc(F)c2)c(C#N)c2nc3ccccc3n12 +Cc1c(-c2nsc(N(C)C)n2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NC4CCC(NS(=O)(=O)CCC(F)(F)F)CC4)nc23)N1 +O=C(Nc1ccc(CCC2CCCCN2)cc1)c1ccc(Cl)cc1 +O=C(O)CC(=O)N1CCC(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(C2CCCCC2)cc1 +CCC(c1ccc(-c2ccc(F)cc2)cc1)N1CCC(CCCO)(c2ccccc2)OC1=O +Cc1ccc(NC(=O)Nc2cc(-c3cc(Cl)cc(C(=O)O)c3)ccc2Oc2ccccc2C(C)(C)C)cc1 +CCCN(CCN1CCN(c2ccc(-c3ccccc3OC)cc2)CC1)C1CCc2nc(N)sc2C1 +O=C(Cc1ccc(O)cc1)Nc1nc(-c2ccncc2)cs1 +O=C1NC(=O)C2=C1c1cn(c3ccccc13)CCOC(CN1CCOCC1)CCn1cc2c2ccccc21 +Cc1cncc(C2C(C#N)=C(N)Oc3cc(N(C)C)ccc32)c1 +CC1CCC2C(C)C(OCc3cccc(CN4CCN(c5ccc(Cl)cc5)CC4)c3)OC3OC4(C)CCC1C32OO4 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(CN5CCOCC5)s4)nc23)N1 +O=C(C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2)Nc1cccc(F)c1 +CCCCNC(=O)c1ccc2c(c1)nc(NC(=O)c1cccc(C#N)c1)n2CCCOC +COC(=O)N1CCOC(C(=O)N2CCC(c3cc(-c4ccncc4)c(-c4ccc(F)cc4)[nH]3)CC2)C1 +C=CCN1CCC23c4c5ccc(O)c4OC2c2c(c4ccccc4n2C)CC3(OC)C1C5 +CCC(Nc1ccc(Cl)c(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 +Cc1ccc(C2(c3nc4ccc(N5CCCC(C(=O)N6CCCC6)C5)nc4[nH]3)CC2)cc1 +CC(C(=O)OC1C[N+]2(CC(=O)Nc3cncc(Cl)n3)CCC1CC2)(c1cccs1)N1CCCCC1 +CC(C)Nc1nc2ccc(C#N)cc2nc1N1CCC(C(F)c2ccc(F)cc2F)CC1 +NC1CCC(Nc2nccc(Nc3cc(C4CC4)[nH]n3)n2)CC1 +CC1(C)SCN(CCCCN2CCN(c3cccc(C(F)(F)F)c3)CC2)C1=O +Cc1ccc2cc(C(=O)NC3(C(=O)NC(CCCN4CCN(Cc5ccsc5)CC4)Cc4ccccc4)CCCC3)sc2c1 +CN(C)C1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCOC5)c4n3)nc2)CC1 +NS(=O)(=O)c1ccc(CNC(=O)OCCCCc2ccc(N(CCCl)CCCl)cc2)cc1 +CC(=O)N1Cc2cc(-c3ccc(C#N)cc3)ccc2CCc2cc(Cl)ccc21 +N#Cc1c(-c2ccc(S(=O)(=O)NC(CO)CO)cn2)n(C2CCC2)c2cc(OC(F)F)ccc12 +COC1CCC(=Cc2sc(-c3ccc(C)cc3)nc2O)CC1 +Cc1cccc(NC(=O)c2nccc3c(-c4ccccn4)c[nH]c23)n1 +CCCCc1nn(C(C)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCS(=O)(=O)CCCc1ccc(-c2nnc(-c3ccccc3C(F)(F)F)n2C)c(C)c1 +CCCCCn1c2ccccc2c2cc(CN3CCN(C)CC3)ccc21 +Cc1ncc(-c2ccc(C(=O)N=c3[nH]c4cc(CN(C)c5ccccc5)ccc4n3CC(C)(C)O)s2)o1 +CC(=O)OCCOc1ccc2c(c[n+](C)c3c4cc5c(cc4ccc23)OCO5)c1O +COc1ccc(CNC(=O)Nc2cc(-c3cccnc3F)ccn2)cc1 +COCCN(C(=O)c1cnc(-c2cccc(C)c2C)cn1)c1ccc(OC)nc1 +CC1CCCN1CCc1cc2cc(Nc3ccc([N+](=O)[O-])cn3)ccc2o1 +CCOc1ccc(-n2c(C)c3c(C)nnc(NC4CCc5ccccc54)c3c2C)cc1 +COc1ccc2cc(O)c(C(=O)NCc3ccc(Cl)cc3)cc2c1 +COc1ccc(OCC(=O)Nc2cccc(-c3nc4ncccc4o3)c2)cc1 +Cc1nc2cnc3ccc(C#CCNC(=O)c4cccn(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C(C)C +NC1=NC(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)(C(F)F)C2CC2O1 +[C-]#[N+]c1ccc(N2C(=S)N(c3ccc(C)cc3)C3(CCC3)C2=NC)cc1C(F)(F)F +c1ccc(Cn2ccc3nc(-c4ccccc4)nc-3c2)cc1 +O=C(c1ccccc1-n1nccn1)N1C2CCC1C(Nc1nc3cc(Cl)ccc3o1)C2 +N#Cc1ccc2[nH]c(C3CCC4(CC3)CN(c3ccccn3)C(=O)O4)nc2c1 +Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(C)c3ccc(C(C)C)cc3)cc12 +O=C(NO)C1CCCC1C(=O)Nc1ccc(OCc2cc(Cl)cc(Cl)c2)cc1 +CC(O)(c1ccc(C(=O)N(CC2CC2)C2CCCCC2)cc1)C(F)(F)F +CCOC(=O)C1=C(Nc2ccc(C)c(C)c2)SCC1=O +CNc1nc(C#Cc2ccc(Cl)s2)nc2c1ncn2C1C(O)C(O)C2(C(=O)OCCc3ccccc3)CC12 +CN(C)c1ccc(C#Cc2ncnc(N)c2C2CCCCC2)cc1 +Cc1cccc(OCc2n(C)c3ccccc3[n+]2CC(=O)OC2CC(C)CCC2C(C)C)c1 +c1ccc(C2=NC(CN3CCN(c4ccccc4)CC3)CO2)cc1 +COc1ccccc1N1CCN(CCCNC(=O)Cc2ccc3ccccc3c2)CC1 +CCOC(=O)CNC(=O)C=Cc1oc2ccc(Cl)c(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc43)c2c1C +COc1cccc(N(C)c2ccnc(Nc3cc(N4CCOCC4)cc(N4CCOCC4)c3)n2)c1 +CN1CC(CS(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CC2CC2)C1 +Clc1cccc(CNCCC2(c3ccccn3)CCOC3(CCCC3)C2)c1 +O=c1[nH]c(Cc2nnc(Nc3ccccc3)s2)nc2sc3c(c12)CCCC3 +Cc1ccc(-c2ncc(C(=O)NC3CCCCC3)nc2-c2ccc(C)cc2)cc1 +CC(C)=CCOc1cccc2c1-c1c(c3c(n1C(C)C)CCCC3=O)C2=O +CCOC(=O)C(C(=O)NCCc1ccccc1)[n+]1ccc2ccccc2c1 +Cc1ccc(C23COC(C4CC4)CC2CSC(N)=N3)c(F)c1 +O=C(c1ccc(OCCN2CCCCC2)cc1)c1oc2cc(O)ccc2c(=O)c1-c1ccc(O)cc1 +Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(-c3ccsc3)cn2)cc1 +Nc1nccc(-c2cc3c(n2CC2CC2)CCNC3=O)n1 +O=C(O)CC1CCN(CCOCCN2c3ccccc3CCc3ccccc32)C1 +Clc1cccc(N2CCCN(CCCOc3ccc4scnc4c3)CC2)c1Cl +Clc1cccc(C(Nc2ccnc3cc(Cl)ccc23)c2ccc(CN3CCN(c4ccnc5cc(Cl)ccc45)CC3)c(Cl)c2)c1 +CCCN(CCC)C(=O)C1CCC(NC(=O)c2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CN1Cc1c(F)cccc1OC +CC(C)C(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1N1CCC(CN2CCCC2)CC1 +CC1CN(Cc2ccccc2)c2ccccc2C(C)N1C(=O)NC1COC1 +O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(Cl)c1 +CC1CC1C(=O)Nc1snc(-c2ccc3nn(C)cc3c2)c1-c1cccc(C2CCC2)n1 +CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(N)=O)cc2C4)cc1 +Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(O)c(O)c3)C(C)(C)C2=O)cn1 +COc1cc2nc(N3CCN(C(=O)C4COc5cccc(OC)c5O4)CC3)nc(N)c2cc1OC +CCOC(=O)C1CCC(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)CC1 +NCc1ccc(Oc2cc(Oc3ccc(CN)cc3)cc(C(=O)NC3CCC(N)CC3)c2)cc1 +NC(=O)c1cc(-c2ccncc2)[nH]c1-c1cccc([N+](=O)[O-])c1 +CCCc1cnc(N2CCC(C3Cc4c(F)c(C5=CCN(S(=O)(=O)CCC(C)(C)O)CC5)cc(F)c4O3)CC2)nc1 +CCCN(CCC)CCc1ccc(OC)cc1OCCc1ccccc1 +CN1CCNC(C(=O)NC(Cc2ccc(F)cc2)C(=O)N2CCC(CC3CCC3)(C(=O)NC(C)(C)C)CC2)C1 +COc1cc(-n2c(SCc3c(F)cccc3Cl)nc3c2C(c2ccc(Cl)c(OC)c2)CCC3)ccc1F +COC(=O)C1CC(C(=O)NCc2c(F)ccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 +CC(=O)OC1c2c(c3c(c4c(-c5ccccc5)cc(=O)oc24)OC(C)(C)C=C3)OC(C)C1C +COc1ccc(CNC(=O)c2cnc3nc(C)ccc3c2O)cc1 +COc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(=O)c1cccc(CO[N+](=O)[O-])c1Cl)CC2 +COc1cc(Cl)ccc1CC1(O)CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 +NS(=O)(=O)c1cc2c(s1)S(=O)(=O)CCC2O +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)(C)c2cccc(C#N)c2)c1 +COc1cccc2c1CCCC2CCCCCN1CCN(C2CCCCC2)CC1 +CS(=O)(=O)C1CCN(c2ccc(C(=O)NCc3cn(-c4ccccc4)c4cc(Cl)ccc4c3=O)cn2)CC1 +CC(C)C(=O)NCc1ccc(Cl)c(-c2nc3cc(Cl)c(N4CCC(C(F)F)CC4)cc3c(=O)[nH]2)c1 +CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3cccc(C(F)(F)F)c3)c2)CC1 +O=C(O)C1CCCN(S(=O)(=O)c2ccc(-c3ccccc3Cl)cc2)C1 +O=C(CCCCN1CCOCC1)Nc1ccc(-c2cccnc2F)cc1 +CN1CCC(C(=O)OCc2ccccc2)(c2ccc(-c3ccccc3)cc2)CC1 +CC(O)(c1ccc(N(CC2CC2)S(=O)(=O)c2ccccc2Cl)cc1)C(F)(F)F +COCCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccnc(OC)c3)cc2s1 +COc1cc(C(=O)c2c(-c3ccncc3)[nH]c3ccccc23)cc(OC)c1OC +CC(C)C(NC(=O)OCc1ccccc1)C(=O)c1nc2c(OC(=O)C(C)(C)C)cccc2o1 +CCC(=O)NCCN1CCCc2c(-c3ccc4c(c3)CCC(=O)N4C)cncc21 +O=C1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2CCN1CC(F)(F)F +COC(C)(C)CCn1nc(Nc2c(C)cccc2C)c2cnc(Nc3ccc(OCCN4CCCC4)cc3)nc21 +O=C(O)c1cc(N(Cc2ccsc2)Cc2cccs2)[nH]n1 +CC1CN(C(=O)Nc2nc3cc(F)ccc3s2)CCN1c1ncc(C(O)CO)cc1F +Cc1ccc(C(=Cc2ccccc2)C(=O)N2CCc3ccc(C(=O)NO)cc3C2)cc1 +Nc1cc(C(=O)N2CCCC2)cn2nc(-c3ccco3)nc12 +O=c1c2cn[nH]c2c2ccc(-c3cccc(N4CCN(C5CC5)CC4)c3)cc2n1CC(F)(F)F +Cc1cc2cc(NC(=NC3CCCCN(CC(=O)N4CCCC4)C3=O)C(C#N)=C(O)OCCCCO)ccc2o1 +COc1cc2nc(C(C)C)n(-c3ccccc3)c2cc1OCc1ccc2ccccc2n1 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1c(Cl)c(Br)cc2ccc(O)cc12 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1c(-c2cccc(OC(F)(F)F)c2)nc2sccn12 +NC(=O)c1nc(-c2ccncc2)sc1NC(=O)c1ccc(CCCCCC(=O)O)cc1 +CCC(C)C1NC(=O)C(Cc2ccc(OC)cc2)NC(=O)C(CCCCCN(O)C=O)NC(=O)C2CCCCN2C1=O +Cc1cccc2c1N(CC(=O)NC(C)(C)C)C(=O)C(NC(=O)Nc1cccc(Cl)c1)CC2c1ccccc1 +COc1cccc(CCNC(=O)c2cnc(C#N)nc2NCC(C)(C)C)c1 +OCc1cc(C(O)CNCCc2ccc(Nc3cccc(-c4ccccc4)c3)cc2)ccc1O +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cccc(S(=O)(=O)Nc3cccc(C(=O)O)c3)c2)c1 +CCc1nn(Cc2ccc(C(=O)NCc3ccc(Cl)c(Cl)c3)cc2)c(CC)c1CC(=O)O +CC1CN(Cc2cccnc2)CCN1Cc1ccc(C(=O)Nc2ccc(C#CC34CC5CC(CC(C5)C3)C4)cc2)cc1 +O=C1OC2(CCC(c3nc4cc(Cl)ccc4[nH]3)CC2)c2ccccc21 +CCC(NC(=O)N1CCc2cnc(NC(C)CO)nc2C1)c1ccc(F)c(F)c1 +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(Cn3cnc(Br)c3)cc2n1 +O=C(Cc1ccccc1)NCc1ccc(-c2nc(C(=O)N3CCCC(F)(F)C3)co2)cc1 +O=C1N(CC2CC2)C(Cc2ccc3ccccc3c2)C(O)C(O)C(Cc2ccc3ccccc3c2)N1CC1CC1 +C=C(c1cc(OC)c(OC)c(OC)c1)c1c[nH]c2cc(OC)ccc12 +COc1cc2c(cc1OC1CCOCC1)Cc1c-2n[nH]c1-c1ccc(-c2ccc(O)cc2)cc1 +Cc1cc(-c2cccc(NC(=O)C(Cc3ccccc3)NCc3cscn3)c2)ccn1 +Cc1nc(NC2CCNc3ccccc32)cc(-c2ccc3ncsc3c2)n1 +CC(=CC(C)NC(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1)[N+](=O)[O-] +CCOC(=O)c1ccc(NCc2cncn2Cc2ccc(-c3ccccc3)cc2)cc1-c1ccccc1 +COc1ccc(OC)c(CN(C(C)=O)c2cc(F)ccc2Oc2ccccc2)c1 +NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1ccc(Cl)cc1F +O=S(=O)(c1cccc(Cl)c1)N1CCCc2cc(-c3cccnc3)ccc21 +O=C(Nc1cnccn1)Nc1cccc2c1C1CC3(CCN1C2=O)SCCS3 +O=C(Nc1ccc(F)cc1)c1cc2n(c1)CCN(CCc1ccc(CN3CCCCC3)cc1)C2=O +COc1ccc(C2=NN(C3CCN(C(=O)CN4C(=O)CCC4=O)CC3)C(=O)C23CCCC3)cc1OC +O=C(O)c1cc2c(s1)-c1ccc(Cl)c(Cl)c1OC2 +O=S(=O)(c1cccs1)N1CCN(c2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)C(Cc2ccccc2O)C1 +CC(=O)Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1 +Cc1nc(C2CCCCC2)c(-c2ccc(S(N)(=O)=O)c(N)c2)o1 +Cc1cc(CO)cc(Nc2nccc(-n3ccnc3-c3ccccc3)n2)c1 +Fc1cnccc1C(Nc1nnc(-c2c[nH]c3ncccc23)o1)C1CC1 +CC1(C)C2CC=C(CN3CCC(Nc4nc5ccccc5o4)CC3)C1C2 +CCN(CC)C(=O)c1ccc(C2(c3cccc(O)c3)CCN(CC3CC3)CC2)cc1 +Cc1ccc(C=CC(=O)NC2CCC3(O)C4Cc5ccc(O)c6c5C3(CCN4CC3CC3)C2O6)cc1 +Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3OCCO)c12 +c1ccc(-c2cc(-c3csc(Nc4ccc5ccccc5n4)n3)on2)cc1 +Cc1nc(NC2CCCC2C)nc(-n2ccnc2C)c1[N+](=O)[O-] +CCOc1cccc(-c2ccc(NC(=O)C(C#N)=C(C)O)cc2)c1 +CNC(=O)Cn1c(=O)n(C2CCN(C3CCCCCCCCC3)CC2)c2ccccc21 +Cc1coc(-c2ccc(C)nc2C(=O)N2C3CCC2C(COc2ccccn2)C3)n1 +CCC1(O)c2cc3n(c(=O)c2COC(=O)C1OC(C)=O)Cc1cc2cc4c(cc2nc1-3)OCCO4 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+Cn1cc(C#N)c2ccc(Nc3ncc(-c4ccc(CN)cc4)o3)cc21 +COc1ccc2c(c1)c1c(-c3ccc(O)cc3)c[nH]c(=O)c1n2C +COC(=O)C(=O)CCCCCCCOc1ccc(-c2ccccc2)cc1 +CC=C1C2C=C(C)CC1(NC1OCC3=C4CC(C)(C)CC4C(C)C(O)CC31O)c1ccc(=O)[nH]c1C2 +Cc1ccccc1CSc1nnc(Nc2ccc(Cl)cc2)[nH]1 +Cc1cc(C(=O)NCc2ccc3cc(C(=O)NO)sc3c2F)oc1C +OCC1CC(Oc2ccccc2Cc2ccc(F)cc2)C(O)C(O)C1O +Nc1nc(O)c2ncn(CCCCCP(=O)(O)CP(=O)(O)O)c2n1 +Cc1c(C(=O)N(C)C2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Br)cc1 +CCCCCc1nnc(NC(=O)c2ccc(-c3ccc(OC)cc3)cc2)s1 +CC(=O)Nc1cc(C(=O)c2c(C)cncc2N2CCOCC2)cc(-c2cccc3[nH]ccc23)c1 +CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccc(F)cc1 +COC(=O)Nc1nc2ccc(C3(O)c4c(F)ccc(F)c4C(=O)N3c3cccc(Br)c3)cc2[nH]1 +Cc1cc(N2C(=O)OCC2C(C)O)nc(NC(C)c2ccn(-c3ccc(Cl)cc3)n2)n1 +CCC1(CC)C(=O)N(c2ccc(Cl)cc2)C(=O)c2ccccc21 +C=CC1(C)CC(=O)C2(O)C(C)(O1)C(OC(C)=O)C(OC(=O)NCCN(C)C)C1C(C)(C)CCC(O)C12C +CCOC(=O)c1cnn(CC(C)O)c1NC(=O)NCc1ccccc1 +CC1CCC(c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)CC1 +Cc1ccccc1N1CCN(CCC(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2csc(N)n2)CC1 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+CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(OC4CCCC4)cc3)C2)cc1 +C=CCn1c(O)c(N=NC(=S)Nc2cccc(OC)c2)c2ccccc21 +CCCOc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +O=C(NC1CCC(c2cccc(F)c2F)Cc2cccnc21)c1cnc2c(c1)CC1(C2)C(=O)Nc2ncccc21 +N=C(N)c1ccc(C(=O)NCCC2C(=O)N(CC(=O)O)CCN2C(=O)CNC(=O)c2ccc(C(=N)N)cc2)cc1 +CC(Nc1nc(NCC(O)CO)cc(Nc2cc(C3CC3)[nH]n2)n1)c1ccc(F)cc1 +CC(C)c1nn(-c2ccc(C(N)=O)c(NC3CCN(C(=O)CN)CC3)c2)c2nccc(-c3cnc4ccccc4c3)c12 +O=C(CNC(=O)c1ccc(-c2ccccc2)cc1)NC1CCCc2ccccc21 +O=C(O)CNC(=O)c1ncc(-c2cccc(Cl)c2)cc1O +CN1CCC(N(C)C(=O)c2ccc(-c3cc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)s2)C1 +Fc1ccc(-c2cc(-c3ccc(C4CNCCO4)cc3F)n[nH]2)cc1 +Cc1ccccc1-c1ccc(OCC(F)(F)F)c(OC2CNC2)c1 +CN1CCN(CCC(=O)NC2CC3(N4CCN(C)CC4)CC(c4ccccc4)C2C(c2ccccc2)C3)CC1 +CN(C)C(=O)CN1CCN(c2nc(-c3nnc(Cc4ccc(F)cc4)o3)c(O)c3ncccc23)CC1 +O=C1NC(C(=O)O)Cc2ccc(nc2)OCCCCOc2ccc(Cl)c1c2 +COCCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccccc3)cc2s1 +O=C(c1ccccc1Cl)N1CCn2c(-c3ccccc3)cnc2C1 +CC(C)(C)c1cc(-c2nn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)c(=N)s2)ccn1 +Cc1cc(NC(=O)Cc2nc(N3CCOCC3)cc(=O)[nH]2)ccc1F +O=C(NC1CNC(C(=O)N2CCSC2)C1)c1ccccc1 +CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)c2ccccc12 +C=CC1CC23CC(C(OC(=O)CCC(=O)O)c4ccnc5ccc(OC)cc45)N2CCC13 +CCN1C(C)(C)CC(Oc2ccc(C(=O)Nc3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)nc2)CC1(C)C +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C(F)(F)F +COCCOc1cc(O)c(C=O)c2oc(=O)cc(C)c12 +OCCn1cc(-c2cnc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +CNc1nc(Oc2ccc(OC)cc2)nc(N(C)C2(c3ccccc3)CCC(c3ccccc3)(N(C)C)CC2)n1 +CCCCn1cc2c(nc(NC(=O)Nc3ccc4c(c3)COC4)n3nc(-c4ccco4)nc23)n1 +COCCCN1CC(C)N(C(=O)N2Cc3c(NC(=O)c4cnccn4)n[nH]c3C2(C)C)CC1C +O=C(NC1CC1)c1ccc(-c2cnc3c(NCC4CCOCC4)cc(Nc4ccccc4)nn23)cc1 +COc1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)c(C)c3)cc1CC2 +CC(C)CC(NC(=O)C(O)C(S)C(=O)O)C(=O)NCCCCNC(=N)N +CN1CCN(CCN=C(S)Nc2ccc(S(=O)(=O)Nc3ccc(S(N)(=O)=O)cc3)cc2)CC1 +O=[N+]([O-])c1ccc(-n2cnc3ccccc32)c([N+](=O)[O-])c1 +O=C1c2cc(-c3ccnc(NC4C5COCC54)n3)cn2CCCN1C(CO)c1cccc(Cl)c1 +O=C(c1ccc(F)cc1)C1CCN(C2CC(OCc3ccc(F)cc3)CCC2O)CC1 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+O=C(N1CCOCC1)n1nc(-c2ccc(Cl)cc2)nc1SCC(F)(F)F +Cc1ccc(CNC(=O)CC2CCCCN2c2ccnc(-n3ccnc3)n2)cc1 +CCOC(=O)C1(Cc2ccccc2)CCc2cnc3c(-c4ccc(C(F)(F)F)cc4)cnn3c21 +CC1(C)CCN(S(=O)(=O)CCCN2CCC(CNC(=O)c3cccc4c3OCCO4)CC2)CC1 +NS(=O)(=O)c1cccc(NC(=S)NC(=O)c2cccc([N+](=O)[O-])c2)c1 +Cn1cnc2cc(-c3ccc(N4CCC(C)(O)CC4)cc3)nc(NC3CCOC3)c2c1=O +CCC(C)c1cc(C)c(C(=O)N=C(N)N)cc1S(C)(=O)=O +CCCCc1nn(CCCc2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(C2CN(C)Cc3cc(OCCCN4CCC(C(F)(F)F)CC4)ccc32)cc1 +COc1ccccc1-c1ccc(CC(NC(=O)C2(S(=O)(=O)C(C)(C)C)CCCC2)C(=O)O)cc1 +CCc1cc(=O)[nH]c2ccc(N(CC(F)(F)F)CC(F)(F)F)cc12 +CCC(NC(=O)c1cc(C(=O)N(C)CC(=O)OC(C)C)n2c1COCC2)c1ccccc1 +CC(C)(C)c1ccc(CCN2CCc3cc(S(=O)(=O)Nc4ccc(CCCC5CCCC5)cc4F)ccc3C2)cc1 +Cn1c(=O)c2c(CC(=O)Nc3nc(-c4ccc(C(F)(F)F)c(F)c4F)cs3)c(Cl)oc2n(C)c1=O +O=C(NCC1CCC(CCOc2ccccc2)CC1)c1cc[nH]n1 +Cc1cnc2c(C(F)(F)F)cccc2c1-c1cccc(Oc2ccc(S(C)(=O)=O)cc2)c1 +CC1CCC(Cn2c(N3CC(C)OC(C)C3C)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CC1CN(c2ncnc3[nH]cc(-c4cccc(C#N)c4F)c23)CCO1 +COc1cccc(-c2cc(C(=O)Nc3cc4ccc5c(c4oc3=O)NC(=O)C(CCCNC3CCCCC3)O5)ccc2OC)c1 +O=C(c1ccc2[nH]cnc2c1)N1CCCC2c3c(F)cccc3CCC21 +CCCCCCCOCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +OC(CN1c2cccc(-c3cccc(F)c3)c2CCC1c1cccc(OC(F)(F)C(F)F)c1)C(F)(F)F +CC(C)c1ccc(C(=O)N2CCCC2C(=O)N2CCC3C2C(C)C(=O)N3C(=O)C2CC2)cc1 +Fc1ccc(-c2[nH]c3ncccc3c2-c2ccncc2)cc1 +CC(=O)NC(Cc1n[nH]c2ccccc12)C(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(=O)Nc1cc(Nc2cc(Nc3cn(C)cn3)n3ncc(C#N)c3n2)ccc1C +CC(C)C(=O)N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1 +COC(=O)N1CCN(C(=O)c2cc(Sc3cnc(Nc4ccccn4)s3)ccc2C)CC1 +O=C(Nc1ccc(-c2c[nH]c(=O)c3ccccc23)cc1)N1Cc2ccc(CN3CCOCC3)cc2C1 +NCc1ccc2c(c1)C13CCCCC1C(C2)N(CC1CCC1)CC3 +CC(C)CC(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C2NCCC2c2ccc(Cl)cc2)CC1 +Cc1nc(N)nc2c1cc(-c1cnc3[nH]ccc3c1)c(=O)n2C1CCC1 +O=C(Nc1cc(-c2ccccc2)ccc1O)c1ccc(CNc2ccccc2)cc1 +COc1cc(C2CC2)cc(OC)c1-c1csc2c(N(CC3CC3)CC3CCOC3)c(OC)nn12 +CCc1cc(O)c(OC)c(C(=O)NCC2CCCN2CC)c1Br +O=C(C=Cc1cnc(N2CCN(S(=O)(=O)c3ccccc3)CC2)s1)NO +O=S(=O)(c1ccc(-c2ccc3nccc(Nc4ccncn4)c3c2)cc1)N1CCOCC1 +COc1ccccc1Nc1ncc2cc(-c3c(Cl)cccc3Cl)c(=O)n(C)c2n1 +Cn1c2cccc([N+](=O)[O-])c2c2ncnc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c21 +COc1ccc(Oc2nc3ccccc3cc2C(=O)Nc2cccc(S(N)(=O)=O)c2)c(OC)c1 +COc1cccc(Nc2nnc(Cc3ccncc3)c3ccccc23)c1 +c1cnc(N2CCN(Cc3c[nH]c4ncccc34)CC2)nc1 +CC1(C)CC(c2cc(-c3ccc4cc(C(=O)O)ccc4c3)ccc2O)CC(C)(C)C1 +Cc1c(C(=O)Nc2ccc(C(F)(F)F)cc2)cnn1-c1cccc(F)c1 +CN1C2CCC1C(C(=O)O)C(OC(=O)c1ccccc1)C2 +O=C(Nc1nc2ccc(C3(O)c4ccccc4C(=O)N3c3cccc(Cl)c3F)cc2[nH]1)C1CC1(F)F +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4c(F)cccc4F)c3)ncnc12 +CN(C)CCCCCN(C)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccc(-c2ccccc2)cc1 +COCCOc1ccn2c(-c3ccc4cccc(OCCN)c4n3)cnc2c1 +CC1CCC(OCCCCCCN2CC(O)C(O)C(O)C2CO)CC1C +Cc1c(Cn2ccn3c(=O)cc(N4CCOC(C)C4)nc23)cccc1C(F)(F)F +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1cccc(Cn2ccc(C(F)(F)F)n2)c1 +O=C1NC2(CCCC2)C(=O)NC(Cc2cccc(Cl)c2)C(=O)NCC=Cc2ccccc2OCCNC1Cc1ccc(O)cc1 +COc1cc(C(F)(F)F)cc(C2OC(=O)N(C(=O)NCc3cncc4cccnc34)C2C)n1 +CC(C)c1[nH]nc(OC2OC(CO)C(O)C(O)C2O)c1Cc1ccccc1F +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5occc5c4)c3c2)C1 +N#Cc1ccc(-c2cnccc2NS(=O)(=O)C(F)(F)F)cc1 +CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Cl)ccc3O)c(=O)n2C1c1ccc(OC)cc1 +Cc1cc(CC(NS(=O)(=O)c2cccc(Cl)c2)c2nc3ccccc3[nH]2)ccc1C1CC(=O)NS1(=O)=O +COc1ccc(-c2nc(C)c(C(=O)O)n2O)cc1C#N +CCCCC(CN(O)C=O)C(=O)NC(C(=O)c1ccco1)C(C)(C)C +COc1ccc(C(=O)N2CCN(C(=O)c3cc(Cc4n[nH]c(=O)c5c4CCCC5)ccc3F)CC2)cc1 +Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1C(=O)NCCOc1ccc(C(=O)NO)cc1 +CC(C)(C)CN1CCC(NC(=O)c2csc(NC(=O)c3ccc4cc5n(c4c3)C(C)(C)CNC5=O)n2)CC1 +CCc1cn(C2OC(CNC(=O)C3c4ccccc4Oc4c(OC)cccc43)C(O)C2F)c(=O)[nH]c1=O +CC1CN(Cc2ccc(OC3CCCCC3)cc2)C(=O)O1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NCCC(=O)O +N=C(N)c1ccc2cc(C#Cc3ccc(C(=N)N)nc3)[nH]c2c1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3nn(C(F)F)cc3Cl)cs2)CO1 +COC(=O)c1cc(-c2ccccc2C)c2c(c1)N(c1c(Cl)cccc1Cl)C(=O)NC2 +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5cccc(C(F)(F)F)c5)C4)c3)nc2n(CCC)c1=O +COc1ccc(-c2cc3ncccc3c(OC(C3CNC(=O)C3)C(F)(F)F)n2)cc1OC +O=P(O)(O)CNC(CC#Cc1ccccc1)c1nn[nH]n1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(Cc2ccccn2)CCO1 +COC1CCC2(CC1)Cc1ccccc1C21N=C(N)N(C)C1=O +NNC(=O)c1cc(C23CC4CC(CC(C4)C2)C3)c2ccccc2n1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCCN4CCOCC4)c3)s2)nn1 +Cc1cccc(NC(=O)c2cccc(N3CCc4c(cnc5ccccc45)C3)c2)c1 +CC(O)C(Nc1ccc(C#N)c(Cl)c1Cl)c1nnc(-c2ccccc2)o1 +CCc1cc(C#N)cc2c(NCc3ccc(OC)c(Cl)c3)c(CO)cnc12 +CCCOc1cc2c(cc1C1CCCc3oc(C=CC(=O)O)cc31)C(C)(C)CCC2(C)C +Clc1ccc2c(NCCCNc3nccc(Nc4ccccc4)n3)ccnc2c1 +CS(=O)(=O)N1CC2(CCN(C(=O)C(COCc3ccccc3)NC(=O)C(N)CO)CC2)c2ccccc21 +N#Cc1c(N)n(-c2cccc(S(N)(=O)=O)c2)c2nc3ccccc3nc12 +CN1CCN(c2ccc(NC=C3C(=O)NC(=O)c4ccc(-c5ccoc5)cc43)nn2)CC1 +CCCn1c(=O)c2c(nc(C=Cc3cccc(F)c3)n2C)n(CCC)c1=O +Fc1cccc(F)c1-c1ccc2[nH]nc(-c3cncc(N4CCNCC4)n3)c2c1 +c1ccc(C2CC3(N4CCCC4)CCN(CCCN4CCCCC4)C2C(c2ccccc2)C3)cc1 +COc1cc(OC)c(NC2=CC(=O)C(=O)c3ccccc32)cc1Cl +Cc1nnc(C)n1-c1ccc(OC2c3cc(Cl)cc(Cl)c3CC2N2CCCNCC2)cc1 +N#Cc1cccc(CSc2ncnc3c2ncn3C2OC(CO)C(O)C2O)c1 +O=C(NCCc1ccc(F)cc1)N1CCN2C(=O)c3ccncc3C12c1ccc(Cl)cc1 +Cc1nc(NC(C)c2cccc(Br)c2)cc(-c2ccc3scc(C)c3c2)n1 +C[N+]1(CCOc2ccccc2)CCC(N2CC(c3ccccc3)(c3ccccc3)NC2=O)C1 +C=C1C(=O)C23CCC4C(C)(C)CCCC4(C)C2C(O)CC1C3 +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCN(CCO)CC1 +COc1ccc(Cn2c(=O)ccc3ccc(-c4ccncc4)cc32)cc1 +CCCCCCCCN(CCCCCCCC)C(=O)NC(=O)Nc1c(C(C)C)cccc1C(C)C +O=C(Nc1cccc2c1CC(O)C2)NC1CCC(c2ccccc2)C1 +Oc1ccccc1CNCCCCNc1c2c(nc3ccccc13)CCCC2 +CCCC(CCC)(CNC(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1 +Cc1cccc(CNc2cc(N3CCOCC3)cc(CSc3nc(C)c(C)o3)n2)n1 +CCN1C(=O)CCC1C(=O)NCc1cccc(C(F)(F)F)c1C#N +COc1ccc(S(=O)(=O)N(CCCCc2ccccc2)CC(=O)NO)cc1 +Cc1nc(NCc2cccc(F)c2)nc(-n2ccnc2C)c1[N+](=O)[O-] +CC(=O)N1CCc2nc(N3CCC(C(F)c4ccc(F)cc4F)CC3)c(NC(C)C)nc2C1 +CCCCCCc1c(C(=O)CC(C)CC(=O)O)c2cc(Br)ccc2n1C +CS(=O)(=O)Nc1ccc2c(c1)C(N1CCCC1)c1cc(-c3ccccc3)cnc1C=C2 +CC(C)(O)CCc1cn(Cc2ccc(F)cc2)c2cnc3c(c12)CCN(O)C3=O +COC1CN(CC(=O)Nc2ccc(-n3ccccc3=O)cc2F)CC1NC(=O)c1ccc(Cl)s1 +C=C(C)C12CC(C)C34OC(c5ccccc5)(OC1C3C1OC1(CO)C(O)C1(O)C(=O)C(C)=CC14)O2 +NC(=O)c1ccc(Oc2ccc(CCN3CCc4ccccc4C3)cc2)nc1 +Cn1cc(-c2cnc3nnn(Cc4ccn5nccc5n4)c3n2)cn1 +Cc1cc(C(=O)Nc2ccc3ccccc3c2)c(C)n1-c1ccccc1 +O=C(O)CCC(NC(=O)NC(CCCCn1cc(COCCOCCNc2ccccc2)nn1)C(=O)O)C(=O)O +Nc1ncc(-c2cnn(C3CCN(CCO)CC3)c2)cc1-c1nc2ccc(F)cc2o1 +COCCN1CC2C(C1)C2c1cc(-c2cnc(N)c(C(F)(F)F)c2)nn1CC1CCC1 +O=C(Nc1ccc(OCC2CC2)c(C(F)(F)F)c1)N1CC=C(c2ncc(CO)cc2Cl)CC1 +COc1ccc(C2C(C(=O)O)C(c3ccc4c(c3)OCO4)CN2CC(=O)Nc2c(Br)cccc2Br)cc1 +CC(=NOCCN)c1ccc(Nc2c3ccccc3nc3occc23)cc1 +Cc1ccc(C(=O)Nc2ccccc2)cc1-n1cnc2ccc(N3CCN(C)CC3)cc2c1=O +OCCN(CCO)CCCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +COc1ccc(C(NC(=O)Cc2ccc(Cl)cc2)NC(=O)Cc2ccc(Cl)cc2)cc1 +COc1ccc(C=C2SC(c3ccncc3)=NC2=O)cc1 +O=C(c1ccc(Cl)cc1Cl)N1CCn2c(nc(C(F)(F)F)c2-c2ccc(F)cc2)C1 +Cc1nc2ccccc2nc1NC(CC(C)C)c1ccc(C(=O)NCCC(=O)O)cc1 +OCCN1CCN(c2cc(-n3ccnc3Nc3cc(Nc4ccc(OC(F)(F)F)cc4)ncn3)cc(C(F)(F)F)c2)CC1 +O=S1(=O)C=C(c2ccccc2Cl)S(=O)(=O)CCC1 +COc1cc(F)c(-c2nc(C(=O)Nc3cnn(C)c3N3CCC(N)CC(F)(F)C3)c(N)s2)c(F)c1 +CC(C)(C)c1cc(N2CCC(=O)NC2=O)cc(C(=O)Nc2ccc(NS(C)(=O)=O)cc2)c1O +CC(C)CC(NC(=O)N1C(C)(C)CCCC1(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCC(=O)O +CC(=O)Oc1ccc(C(=O)NCCOC(=O)C2CCC3CN2C(=O)N3S(=O)(=O)O)cc1OC(C)=O +COC(=O)c1cccc2c3c(c(CC(C)C)cc12)C(=O)NC3=O +Cc1cc2c(cc1C1CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CO1)COC2=O +CS(=O)(=O)N1CCN(Cc2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3o2)CC1 +CNc1nc(C)c(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)s1 +COc1cccc2c1c(C(=O)C=C(O)C(=O)O)cn2Cc1ccc(F)c(Cl)c1 +O=S(=O)(Nc1ccc(Oc2cnc3ccccc3c2)c(F)c1)c1ccc(Cl)cc1Cl +O=C(N1CCOCC1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2cccc(F)c21 +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(C5CCN(CCO)CC5)cc4)c3)c(OC(C)C)cc21 +O=C(c1n[nH]c2c1CNCC2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 +CCNC(=S)Nc1cc(-n2cnc(CN3CCOCC3)c2)ncn1 +CC(C)(C)c1oc2ccccc2c1SC1=C(O)OC(CCc2ccccc2)(c2ccccc2)CC1=O +CN1CCN(c2ccc(Nc3nccc(-c4ccc(C(=O)NCC#N)cc4)n3)cc2)CC1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NN4CCCC4)nc23)N1 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+CC(C)C(=O)N1C2C=C(CN3CCC(NC(=O)Nc4cc(F)cc(C(F)(F)F)c4)CC3)CC1CC2 +CN(C)CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC1CCOC1 +COc1cc(C(=O)NC2CCC3(O)C4Cc5ccc(O)c6c5C3(CCN4CC3CC3)C2O6)ccn1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCN(CCC(c2ccccc2)c2ccccc2)CC1 +CC1=CC(C)(C)Nc2ccc(-c3ccc(Br)s3)cc21 +COc1ccc(NC(=O)c2ccc(Cl)c(Nc3ncnc4cnc(NCCN5CCOCC5)nc34)c2)cc1C(F)(F)F +Cc1cc2c(cc1Cc1ccc(-c3cscn3)cc1)C(=O)N(C1CCOCC1O)CC2 +COc1ccccc1-c1ccc(CC(NC(=O)C2(c3ccccc3)CC2)C(=O)O)cc1 +O=C(NC1CCC(Oc2ccnc3c(Br)cccc23)CC1)c1cccc(F)c1 +O=C(Nc1ccc2c(c1)NC(=O)C(CCO)O2)C1CCN(c2cc(F)c(F)c(F)c2)CC1 +CN(C)CCNc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(C#N)cc12 +COc1ccc(C(=O)Nc2ccc(C3CNCCO3)cc2)cc1 +CN1CCN(c2nc3sc4ccccc4n3c(=O)c2C(N)=O)CC1 +Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1ncnc2[nH]c(C3=CCC(O)CC3)cc12 +CC(C)c1ccnc(NC2=NCC3(CN4CCC3CC4)O2)n1 +O=C(Nc1ccc(F)cc1)N1CCn2cccc2C1c1ccc(C(F)(F)F)cc1 +O=CC(Cc1ccccc1)NC(=O)C(NC(=O)OCc1ccccc1)c1ccccc1 +Cc1[nH]c(C=C2C(=O)Nc3ccccc32)c(C)c1-c1ccc(NCCN)cc1 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+O=C(CSSCC(=O)NCCCCCC(=O)Nc1nc(-c2ccccc2)cs1)NCCCCCC(=O)Nc1nc(-c2ccccc2)cs1 +COc1ccc2nc3cc(Cl)ccc3c(Nc3cccc(N4CCOCC4)c3)c2c1 +CN(C)CCOc1ccc(C(=O)NCc2ccnc(C#N)n2)cc1C(=O)C(C)(C)c1cc(Cl)cc(Cl)c1 +COc1cc2c(cc1OC)C(=Cc1ccc(NC(=O)Nc3ccccc3)cc1)C(=O)N2 +COc1ncnc(Cn2cc(C(=O)NCC(F)F)c3ncc(C)cc32)c1C +CN(CC=CC=Cc1ccccc1)Cc1ccc2c(c1)CCCCC2 +CNc1cccc(CCOc2c(C)cc(CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2C)n1 +CN1CCCN(C(=O)c2ccc(Cl)c(-c3ccc(C=C4C(=O)Nc5ccc(Cl)cc54)o3)c2)CC1 +O=C(c1ccc(Cl)cc1)N1CCN(c2ccc(OC3CCN(C4CCCC4)CC3)cc2)C(=O)C1 +CS(=O)(=O)c1cc(C#N)ccc1C1NC(=O)N(c2cc(C(F)(F)F)ccn2)C2=C1C(=O)CC2 +CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C(C)=O)cc4)cc3)nc2n(CCCOC)c1=O +Cc1noc(CCC2CCC(c3ccc(N4CCOc5ncnc(N)c5C4=O)cc3)CC2)n1 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1Nc1cc(OCCO)ccc1CC2 +Cn1ncc(S(=O)(=O)N2CC(CNC(=O)c3ccc(Cl)cc3Cl)(CC3CC3)C2)n1 +CN1CCCC1C(=O)N1CCC(OCCOc2ncc(-c3nc(C#N)nc4c3ccn4C)cc2C(F)(F)F)C1 +O=C(NC(c1ccc(Cl)c(Cl)c1)c1cnco1)N1CCc2cnc(NC3CCOCC3)nc2C1 +COc1cc2c(cc1O)C1CC(O)(c3ccc(Cl)cc3)CCN1CC2 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+O=C(O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(CC(=O)O)c4)s3)s2)c1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3ccccn3)cc2)C(=O)C(C)C)c1 +COCn1c2c(c3ccccc31)CCN(CCCCC13CCCc4cccc(c41)NC3=O)C2 +CC1CC(C)CN(Cc2ccc(-c3cnc4[nH]c5cnc(C#N)cc5c4c3)cc2)C1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(F)cc2)cc1)P(=O)(O)O +CCCCSc1nc(Nc2cccc(O)c2)c2cnn(CC(Cl)c3ccccc3)c2n1 +COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(C2CC2)nc1OCCOc1ncc(Br)cn1 +OC1CN(Cc2cccc(Br)c2)CCC1N1CCN(c2ccccc2)CC1 +O=c1cc(OCc2ccccc2)ccn1-c1ccc(OCCN2CCCCC2)cc1 +CCc1nc(N)nc(N)c1C#CC(C)c1ccc(-c2ccccc2)cc1OC +CCc1ccccc1NC(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CC(C)(C)c1nnc(NC(=O)c2ccc3c(c2)OCCO3)s1 +Cc1c(C(=O)NC(C)(C)c2noc(C(F)(F)F)n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCC(CC)CNC(=O)C1C(C(=O)NCCCCN2CCCC2)C2C=CC1C21CC1 +Cc1c(-c2nnnn2Cc2ccccc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1ccc(-n2nc(C3CCN([S+]([O-])c4sc(C)nc4C)CC3)cc2NC(=O)c2cnn3cccnc23)cc1 +Cc1ccc(C(c2ccccc2)N2CCN(C(=O)CC(c3ccccc3)c3ccccc3)CC2)c(C)c1 +COc1nc2ccc(F)cc2nc1NC(=O)N1CCN(c2cc(C)cc(C)c2)CC1 +O=C1C(Nc2ccccc2Br)=C(Cl)C(=O)c2ncncc21 +c1ccc2ncc(Nc3ccnc(Nc4ccc(OCCCN5CCCCC5)cc4)n3)cc2c1 +COc1ccc(S(=O)(=O)n2cc(C3CCCNC3)c3ccccc32)cc1 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCC(O)C2)c(-c2cccnc2F)c1 +CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1 +COc1cc(=O)n2c3c(cccc13)OC(C1=NCCN1)C2 +Cc1cc(CC(=O)O)ccc1-c1ccc(-c2nc(C(N)=O)c(C)nc2C)cc1 +c1ccc(-c2[nH]c3ccccc3c2-c2ccccc2)cc1 +CN(C)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1 +OCC(O)CN1C(CCc2ccc3c(c2)OCO3)CCCC1CCc1ccc2c(c1)OCO2 +NS(=O)(=O)c1cccc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)c1 +O=C(c1ccccc1F)c1cc(F)ccc1C=COCCN1CCCC(C(=O)O)C1 +O=C(O)c1cc2[nH]c(-c3ccc(OCc4cccc(C(F)(F)F)c4)cc3)c(C3CCCCC3)c(=O)n2n1 +COc1cc(CN2CCOC(COc3ccccc3)C2)ccc1Cl +CC1(C)CC2CC(C)(CN2C(=O)c2cc(Cl)c(-c3cccc4ccccc34)cc2Cl)C1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1csc(-c2ccccc2)n1 +CNC(=O)c1ccccc1Nc1cc(Nc2ccc(N3CCOCC3)c(C)c2)ncc1C(F)(F)F +COc1ccc(CNC(=O)c2ccc(OC)c(OC3CCCC3)c2)c(C(F)(F)F)c1 +N#CCC1(n2cc(C(N)=O)c(Nc3cncc(F)c3)n2)CCN(C(=O)OCC(F)(F)F)CC1 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+CN(Cc1ccno1)C(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C +NC(=O)c1cn(-c2ccccc2)c2c1CCc1cnc(NC3CCCC3)nc1-2 +CC(Nc1nc(-n2cnc3ccncc32)nc2c1cc(C(=O)N1CCN(C)CC1)n2C)c1ccccc1 +COc1cc(-c2cn(C3CCC(N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NS(=O)(=O)c1ccccc1 +CN1C(=O)CC2C3CCc4cc(OS(N)(=O)=O)ccc4C3CCC2(C)C1=O +CCCCCCCCCCCCC(O)C1CCC(C(O)CCCCC(O)CCCCCCCC2=CC(C)OC2=O)O1 +CN1CCN(c2nccc(-c3c[nH]c4ncccc34)n2)CC1 +CC(C)CC(C(=O)NCC#N)c1cccc(-c2ccccc2)c1 +Cn1nc(-c2ccc3c(c2)CC2CCC(C3)C23CN(CC(F)(F)F)S(=O)(=O)N3)cc1-c1ccccc1F +COCCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +NC(=O)c1cc(N2CCN(C(N)=O)CC2)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +Cc1noc(C)c1COc1ccc(S(=O)(=O)N(CC(C)C)c2ccc(Cl)cc2)cc1 +O=C(Nc1ccc(Oc2cccc(C(=O)Nc3ccc(N4CCOCC4)cc3)c2)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +CN1CCN(S(=O)(=O)c2ccc(-c3ccc4c(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)nncc4c3)cc2)CC1 +CN1CCCCCCCCCC(=O)OCC2C(CC3CCC2N3C)c2ccc1cc2 +O=S(=O)(c1ccccc1)N1CCN(c2ncccc2C(F)(F)F)CC1 +CC1(C)CCC(NCCCCN(CC2Cc3ccccc3CN2)C2CCCc3cccnc32)CC1 +CCCSc1nc2c(C)cc(C(=O)NCC(C)c3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=S(=O)(Nc1n[nH]c2nc(Oc3ccc(F)cc3F)ncc12)c1ccccc1 +N#Cc1cc(N2CCOc3cc(S(=O)(=O)Nc4nccs4)ccc32)ccc1F +N=C(N)NCCCC(NC(=O)CN1CCCC(CCC2CCNCC2)C1=O)C(=O)c1nccs1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc(Nc3ncnc4ccc(N)cc34)c2)cc1 +Oc1ccc(C2Nc3ccc4ccccc4c3C3C=CCC32)cc1 +COc1ccc2c(c1)C(=O)C(c1ccc(N)cc1)=[N+]2[O-] +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1ncnc2c(N)nc(N3CCN(C(C)C)CC3)nc12 +CS(=O)(=O)N1CCCC(Nc2nc(N3CCOCC3)ncc2-c2cnc3[nH]ccc3n2)C1 +CCOC(=O)NC(Cc1ccccc1)C(O)CN1CC(C)Cc2ccccc2S1(=O)=O +CC1CNC(=O)c2cc(-c3cccc4ccc(Cl)nc34)[nH]c21 +COc1cc(-n2cnc3cc(-c4ccccc4Cl)sc3c2=O)ccc1OCCN1CCCC1 +CC(C)CCNc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CN(CCCN1CCC2(CC1)OCc1ccccc12)C(=O)C(c1ccccc1)c1ccc(F)c(F)c1 +C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(CN3OCCC3=O)c(F)c2F)c(F)c1 +O=C1Cn2c(Cl)cnc(c2=O)NC(Cc2ccccc2)CNCCCCCOc2ccc(Cl)cc2CN1 +CN1C2CCC1C(C(=O)C(F)(F)F)C(c1ccc(Cl)cc1)C2 +COCCOc1cnc2c(c1)CN(CCn1ncc3c1nc(N)n1nc(-c4ccco4)nc31)CC2 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+COc1ccc2c3c1OC1c4[nH]c5ccccc5c4CC4(O)C(C2)N(CC2CC2)CCC314 +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(NC2CCS(=O)(=O)CC2)nc1OC1CCC1 +Cc1nc(-c2c(F)cc(Cl)cc2-c2cnc(C(C)NC(=O)C3(NC(=O)c4ccnnc4)COC3)c(F)c2)no1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1-n1cc(-c2cncc(N3CCC3)c2)nn1 +CCNC(=O)NC(=O)C1CCCN1C(=O)C(CC1CCCC1)CN(O)C=O +Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CC(=O)NCc1cnc(N)cn1 +CCCCCC=CCC=CC=CC=CC(Sc1ccc2c(=O)cc(C(=O)O)oc2c1)C(O)CCCC(=O)O +CCOc1cc(=O)n(C)cc1-c1cc(NS(=O)(=O)CC)ccc1Oc1ccc(Cl)cc1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)Nc2ccccc2Cl)cc1 +COc1ccc(NC(=O)Nc2ccc(-c3ncnc4[nH]cc(C)c34)cc2)cc1 +CN(C)C(=O)c1ccccc1CCC(SCCC(=O)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2cccnc2)C1 +CN(C)CC=CC(=O)Nc1ccc(C(=O)Nc2cccc(Nc3nccc(-c4cccnc4)n3)c2)cc1 +CC(C)CC(NC(=S)NCc1ccccc1)C(=O)NC1CCOC1O +O=C1C2CCCN2C(=O)N1CCCCNCCOc1cccc(C(F)(F)F)c1 +CC1(C)C=CC(=O)C2(C)OOC3CC12CCC3(O)CO +Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(Cc3n[nH]c(C)n3)C2=O)c1 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+COC(=O)c1cc(C)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +Nc1ccc(S(=O)(=O)N2c3cc(F)c(F)cc3-c3n[nH]cc3C2C2CC2)cc1 +CCc1nc2ccn(CC(=O)OCc3ccccc3)c(=O)c2n1C1CCc2cc(-c3ccccc3-c3nnn[nH]3)ccc21 +CN1C2CCC1CC(NC(c1ccccc1)c1ccc(Cl)cc1)C2 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1C(=O)CO +CCCN(CC1CC1)c1nc(C)nc2c1n(C)c(=O)n2-c1c(C)cc(C)nc1C +NC(=O)c1[nH]c2ccc(C#CC3CC3)cc2c1S(=O)(=O)N1CCCC1 +COc1ccc(COCC2CCN(Cc3ccccc3)CC2)cc1 +CS(=O)(=O)n1c(-c2ccc(OCCCN3CCCCC3)cc2)cc2ccccc21 +COc1ccc2cc1-c1ccnc(n1)Nc1ccc(OCCN3CCCC3)c(c1)COCC=CCOC2 +CCC(CS(=O)(=O)CC)N1C(=O)C(CC(=O)O)OC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +O=C(O)CCc1ccc(CCCC2(O)CCN(CC3CN(CC4CCCCC4)CC3c3ccccc3)CC2)cc1 +CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc([N+](=O)[O-])cc1 +CC(=O)Nc1cnccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 +Cc1ccc2c(c1)C(N1CCN(CCc3ccccc3)CC1)=Nc1cccnc1N2 +O=C(COc1ccccc1)N1CCCCC1c1nc(-c2cccnc2)cs1 +CC(C)CC(CO)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COCCOc1cc2ncnc(Nc3cc(O)c(Cl)cc3F)c2cc1OC +Cc1nc(O)c2cc(-c3ccc(Cl)c(OCCO)c3)c(C(C)C)cc2n1 +O=C(Nc1c(F)cccc1Cl)c1cnc(Nc2ccc(N3CCNCC3)cc2)nc1NCC1CCCO1 +COc1cc2nc(N3CCN(C(=O)c4cc5ccc(O)cc5oc4=O)CC3)nc(N)c2cc1OC +O=C(C=Cc1ccc(Sc2ccccc2CN2CCN(Cc3ccc4c(c3)OCO4)CC2)c(Cl)c1)N1CCOCC1 +[C-]#[N+]c1cc(-c2ccnc(Nc3cnn(C4CCNCC4)c3)c2)ccc1OCC1CCN(C(C)=O)CC1 +COc1ccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)cc1C +CCOP(=O)(c1ccncc1)N1Cc2ccccc2CC1C(=O)NO +NC(=O)CN1CCC(n2cc(-c3cccc(O)c3)c3c(N)ncnc32)C1 +CN=C1SC(=Cc2cc(C)n(Cc3c(F)cccc3F)c2C)C(=O)N1OC +COc1cccc(CCN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)c1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CC3CC1CC(C(=O)NCc1ccc(S(N)(=O)=O)cc1)(C3)C2 +COc1ccc(S(=O)(=O)C(CCCCc2ccccc2)C(C)C(=O)NO)cc1 +CCn1cc(Nc2cc(NC(=O)c3c(Cl)cccc3Cl)ccn2)cn1 +CC(NC(CCc1ccccc1)C(=O)O)C(=O)N1Cc2ccccc2C1C(=O)O +CS(=O)(=O)c1ccc(C2=C(c3ccccc3)C(=O)C2)cc1 +Cc1n[nH]c2cccc(Oc3cc(C#N)cc(C#N)c3)c12 +CN1CCN(c2ccnc3c2c(C=C2Oc4cccc(O)c4C2=O)cn3C)CC1 +COCCNS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F +COc1ccc(C2=NN(C(C)=O)C(c3cc4ccccc4nc3N3CCOCC3)C2)cc1 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+C=CCN(C)CCCCCCOc1ccc2c(c1)CON=C2c1ccc(Br)cc1 +CC(=O)N1CCCC1C(=O)Nc1ccc(C=Cc2ccc(NC(=O)C3CCCN3C(=O)Cc3ccccc3)cc2)cc1 +Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)c4ccc(N5CCN(C)CC5)cc4)cc23)c1 +COC(Cc1ccc(C#CCCCOc2ccc(Oc3ccccc3)cc2)cc1)C(=O)O +COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4Cl)cc3)cc2[nH]1 +COc1cc(-c2ccc3c(-c4ccccc4)n[nH]c3c2)ccc1O +Cc1c(C)n(CCCN(C)C)c2ncnc(Nc3ccc(F)cc3)c12 +Cc1ccnc2c1C(=NN=C(N)N)CC(c1cc(F)ccc1Cl)C2 +COc1ccc(CCC(OC(=O)C2CCCCN2C(=O)C(c2ccccc2)C(C)C)c2cccc(OCC(=O)O)c2)cc1OC +CCC(=O)c1csc(NC(=O)C(C(C)c2ccccc2)N2C(=O)NC(c3ccc(OCCO)cc3)C2=O)n1 +O=C(c1cccc(-n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)c1)N1CCOCC1 +CN1CCNc2nc(CCOc3ccc(CC(NC(=O)c4c(Cl)cccc4Cl)C(=O)O)cc3)ccc21 +Cn1c(=NNC(=O)CC(C)(C)C)sc2cc(OC(F)(F)F)ccc21 +COC(=O)c1ccc(CON=C2C(=O)N(Cc3nc4ccccc4n3CCNS(C)(=O)=O)c3ccccc32)cc1 +CC1OC(n2cc(-c3ccccc3)c3c(NCC(=O)NC4CC4)ncnc32)C(O)C1O +CC(OC1CCC(NCc2cccnc2)C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CON=Cc1c(N)ncnc1Oc1ccc(NC(=O)Nc2ccccc2)c(Cl)c1 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+O=C(NO)C1CC2(CC2)CNC1C(=O)N1CC=C(c2cccc(C3CC3)c2)CC1 +NCCc1c[nH]c2ccc(OCCCCC(=O)N3CCN(c4ccc(N)cc4)CC3)cc12 +COc1cc(C2=NN(c3ccc(C#N)c(Cl)c3)C(C3CCCC3)C2)ccc1C(=O)O +CN1CCN(c2ccc3c(c2)N(C(=O)Nc2cc(OC(F)(F)F)cc(-c4cccnc4)c2)CC3)CC1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(OCCn4ccnc4)cc3)ncc2F)c1 +Cc1nc(N)ccc1CNC(=O)Cn1c(C)cc(S(=O)(=O)CC2CCC2)c(N)c1=O +CC(C)CC(NCCCN)c1cccc(F)c1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)N2CCCC2=O)CC1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 +CCC(CS(=O)(=O)C(C)(C)C)N1C(=O)C(CC)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +NC(=O)NN=C1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +CC1(c2ccsc2)OCC(=O)Nc2ccc(-c3ccc(C#N)[nH]3)cc21 +Cc1c(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1CC(F)F +NC(=O)CC(NC1=NS(=O)(=O)C2CCCCC2O1)c1ccccc1 +Cc1ccsc1CNC(=O)C(CCc1ccccc1)NC(=O)C(NC(=O)c1ccc(OCc2ccccc2)cc1)C(C)O +CN(C)C(=N)c1ccc(C(=O)Nc2cc(Cl)ccc2C(=O)Nc2ccc(Cl)cn2)cc1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OCCCCO)c(C(=O)O)c2)c1 +CC(O)C1CCC2(O)C3CCC4CC(OCC5OC(O)CC(O)C5O)CCC4(C)C3CCC12C 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+Cc1onc(-c2ccccc2)c1CNCC(O)c1ccc(O)c2[nH]c(=O)sc12 +COC(OC)C1=C(C(=O)OCC=Cc2ccccc2)C(c2ccc(Cl)c(Cl)c2)C(C(=O)O)=CN1 +Nc1ccc2c(c1)C(=O)C(=O)c1cc(N)ccc1-2 +Cn1cnc(S(=O)(=O)N2CC3C(C2)C3(CNC(=O)c2cc(Cl)cc(Cl)c2)CC2CC2)c1 +COc1ccc(C2CC(=O)C3=C(C2)NC(C)=C(C(=O)OC(C)C)C3c2ccc(F)cc2)cc1OC +COC1C(OC(=O)NN2CCOCC2)CCC2(CO2)C1C1(C)OC1CC=C(C)C +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NCCF)c12 +Cn1c(=O)c2c(nc(N3CCCC(N)C3)n2Cc2ccccc2F)c2cc(C(=O)O)ccc21 +O=C(C(=O)N1CCCC(C(=O)NCc2ccccc2)C1)c1c[nH]c2ccccc12 +NC(=O)c1ccc(-c2ccc3c(C=O)c(O)ccc3c2)cc1 +N#CC(CC(N)=O)NC(=O)C1CCCN1C(=O)OCc1ccc(-c2ccc(Cl)cc2)cc1 +Fc1cc2[nH]ncc2cc1-c1ccccc1C(F)(F)F +N#Cc1cccc(-c2nc(C3CCC(C(=O)O)CC3)cc3cccnc23)c1 +Nc1ccc(-c2ccccc2)c[n+]1CCCc1ccc(CCC[n+]2cc(-c3ccccc3)ccc2N)cc1 +N#Cc1ccc(-c2ccc(CNCCCNc3ccnc4cc(Cl)ccc34)s2)cc1 +CC(NC(=O)c1ccco1)C(=O)N1CCCN(CCCOc2ccc(-c3noc(CC(C)(C)C)n3)c(F)c2)CC1 +NC1CC(N)C(OC2OC(CNC(=O)c3ccc4ccc5cccc6ccc3c4c56)C(O)C(O)C2N)C(O)C1O 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+Cc1ccc2c(c1)NC(c1c(F)cccc1C(F)(F)F)C1=C(CC3(CCCC3)CC1=O)N2 +Cc1ccc(C(=O)Nc2cccc(CN3CCN(C)CC3)c2)cc1C#Cc1cnc2ccnn2c1 +COc1cc2c(c(OC)c1)CN1CCc3cc(OC)cc(OC)c3C1C2 +CN1CCN=C1c1cccc(Oc2nc(Oc3cc(C(=N)N)ccc3O)c(F)c(OC3CCN(CC(=O)O)CC3)c2F)c1 +CN(c1nc2ccc(F)cc2s1)C1CCc2c(CC(=O)O)c3ccccc3n2C1 +Cn1cnc2cc(-c3cc(OCc4ncccc4C(N)=O)c4cccnc4c3)ccc21 +COc1cc(CSc2cnc(NC(=O)c3ccc(N(C)C)cc3)s2)cc(C(=O)N2CCN(C(C)=O)CC2)c1 +COC(=O)CCCCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(O)c1 +CS(=O)(=O)c1ccc2c(c1)C(=O)NC(C(=O)NC1(C#N)CC1)Cc1ccc(c(Cl)c1)OCC1OC1CO2 +Cc1ccc2c(c1)Cc1c(C(=O)Nc3ccc(F)cc3)nn(-c3ccc(Cl)cc3Cl)c1-2 +CC1(C)OC(=O)N(C2CCC(n3c(=O)[nH]c4cccnc43)CC2)C1c1ccccc1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N(C)C)nc3)ncc2[S+](C)[O-])c1 +Clc1ccc(CN2CCN(Cc3ccc(-c4ccncc4)cc3)CC2)cc1 +CC1(C)Cc2nc(C3CCCC3)c(C(O)c3ccc(C(F)(F)F)cc3)c(C3CCCCC3)c2C(O)C1 +CC(=O)c1cccc(Nc2nc3ccccc3n3cnnc23)c1 +NS(=O)(=O)c1ccc(-c2c([N+](=O)[O-])no[n+]2[O-])cc1 +CC(c1cccc2c1CNCC2)n1c(=O)oc2cc(S(=O)(=O)Nc3cc(Cl)ccn3)c(F)cc21 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+COc1ccc(F)cc1-c1c(CO)sc2cnc(Nc3ccc(N4CCN(C)CC4)cc3OC(C)C)nc12 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1cccc2ccccc12 +Fc1ccccc1Nc1nc2c(-c3nnc[nH]3)cccc2n2cccc12 +CC1(C)C2CC=C(C[N+](C)(C)Cc3ccc(-c4ccccc4I)cc3)C1C2 +COC(=O)c1cccc2oc(-c3ccc4ccc(OCc5ccccc5)cc4c3O)nc12 +CC1=C(C)C(=O)OC(C(C)(O)C2CCC3C4CC5OC56C(O)C=CC(=O)C6C4CC(O)C32C)C1 +CN(CCC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1)C(=O)c1noc(=O)[nH]1 +COc1ccc2nc3c(cc2c1)CC1(O)C2Cc4ccc(O)cc4C1(CCN2C)C3 +CNC(C)C(=O)Nc1cc(-c2c(C)nc3cccc(C)n23)cc(NC(=O)c2ccc(Cl)cn2)n1 +CC(CCl)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +CN1CCN(c2cc(F)ccc2CNC(=O)c2nc(C3CCOC3)n(C)c(=O)c2O)C1=O +COc1ccc(C(=O)C=C(O)C(=O)O)cc1OCc1ccccc1 +CC(C)(O)CN1CC2C(C1)C2c1cc(-c2cnc(N)c(OC(F)(F)F)c2)nc(N2CC3CC2C3)n1 +O=C(C=Cc1ccc(Br)cc1)N1CCN(C(=O)c2ccccc2)CC1 +O=C(O)c1ccc(Nc2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)cc1 +O=C(Nc1cccc2[nH]c(=O)ccc12)NC1CC(CF)(CF)Oc2cc(Cl)ccc21 +CCn1c(C)c(-c2ccc(CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)c(=O)n(CC)c1=O +Cc1cc(N=S2(=O)CCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NC(CF)CF)c12 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+COc1ccc2[nH]cc(C3CCC(CCN4CCN(c5ccccn5)CC4)CC3)c2c1 +CC(C)(O)c1nc2cc(Cl)ccc2n1C1CCC(NCC2Cc3ccc(Br)cc3C2)CC1 +COc1ccc(-c2cnn3cc(-c4ccncc4)cnc23)cc1 +Cc1ccccc1C=CC(=O)NC(C)c1nc2scc(C)c2c(=O)o1 +Cc1c(NC(=O)Nc2ccccc2)cccc1-c1nc(Nc2ccc(C(=O)N3CCOCC3)cc2)c2nc[nH]c2n1 +COc1ccc(-c2cccc(C(CC(=O)O)c3nnc(C)o3)c2)c(OC)c1 +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3cccnc3)sc12 +COc1cccc(OC)c1C(=O)NC1CCCC1Nc1ncc(C(F)(F)F)cn1 +COc1ccc2c(c1)C(=O)N(c1ccc(N3CCCCC3=O)cc1)CN2C(=O)Cc1ccc(NC(C)=O)cc1 +NCC1CCN(c2cncc(-c3cc4c(-c5ccccc5F)n[nH]c4cn3)c2)C1 +Cc1cccc(Cl)c1S(=O)(=O)C(=O)N1CC2CN(CCC(c3ccccc3)C3CCN(S(C)(=O)=O)CC3)CC2C1 +CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]c(=NC(=O)c1ccc(C=Cc3ccccc3)s1)n2CCC(N)=O +CC1(C)CNC(=O)c2sc(Nc3ccc(I)cc3Cl)c(C(=O)NOCC(O)CO)c2C1 +COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(COC(C)=O)CC12C +CNC(=O)c1ccc(-n2cnc3c(NCC4CCOCC4)cc(Oc4ccc(OC)c(F)c4)cc32)cc1C +COc1cc(C(=O)NCc2cccc(O)c2)ccc1-c1cn[nH]c1 +CC(C)NC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 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+Cc1[se]c(C=C2C(=O)Nc3cc(-c4ccc(O)cc4)ccc32)cc1C(=O)NCCN(C)C +CNC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCOCC3)cc2OC)ncc1Cl +COc1ccc2cc(C3=NCCc4cc(Cl)c(O)cc4N3)ccc2c1 +Cc1cc(C)n(CC(O)Cn2c3ccc(I)cc3c3cc(I)ccc32)n1 +CCCCCCCCCCCCC(O)C1CCC(C(O)CCCC(O)C(O)CCCCC(=O)CCC2=CC(C)OC2=O)O1 +CC1CN(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)CC(C)N1 +COC(=O)c1ccc(CN2CCC(Nc3cc(Oc4c(C)cc(C#N)cc4C)ccc3[N+](=O)[O-])CC2)cc1 +O=C(CC12CC3CC(CC(C3)C1)C2)NC(=S)NCc1ccco1 +CN(CCCCCc1ccccc1)CCN1C(=O)C2Cc3ccccc3CN2C1=O +CCCOC(=O)c1ccc(Oc2ccc3c(c2)COB3O)nc1 +CSCCC(NC(=O)C(Cc1ccccc1)NCC(NC(=O)C(N)CS)C(C)C)C(=O)O +Cc1ccc(-n2nccn2)c(C(=O)N2CCOC2Cn2ccc(-c3ccc(F)cn3)n2)c1 +CC(=O)NC(Cc1ccccc1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)C)cc21 +O=C(O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c3cccc(F)c23)cc1O +Cc1cccc(-c2cnc(Nc3ccc4c(C#N)cn(C)c4c3)o2)c1 +CN(C)C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3[N+](=O)[O-])cc2)c2ccccc21 +O=C(NC1CCN(Cc2ccc3ccccc3c2)CC1)c1ccccc1 +C#CCCCCn1ncc2c(N)c(C(=O)OCC=C)c(C)nc21 +COC(=O)C1=CN(Cc2ccc(OC)c(OC)c2)C=C(C(=O)OC)C1c1cccc(OC)c1OC +Cc1nn(CC(C)(C)O)c(C)c1CC(=O)NCc1ccc(F)c(F)c1F +N#CC1CC(N2CC(O)C2)CCC1n1cc(C(N)=O)c(Nc2ccc(S(=O)(=O)C(F)(F)F)cc2)n1 +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(C(=O)NCCN4CCCC4)cc3)nnc2c1 +NC(=O)c1ccc(-c2ccnc3c(-c4cnc5ccccc5c4)cccc23)cc1NC1CCC(O)CC1 +O=C(C=Cc1ccc(C=C(C(=O)NC2CCCCCCC2)c2ccc(F)cc2)cc1)NO +CCSCCCCNC(CC(C)C)C1(c2ccc(Cl)cc2)CCC1 +COC(=O)c1cccc2c1c(C(=O)CN1CCC(n3c(C)nc4cnccc43)CC1)cn2C(=O)N(C)C +CCCCc1nc(Cl)c(COC(=O)CCCCO[N+](=O)[O-])n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccc2ccn(C)c2c1 +CCCc1ccc(S(=O)(=O)NC(Cc2ccc(CN)cc2)C(=O)N(C)C2CCCC2)cc1 +N#Cc1ccccc1CSc1nnc2c3ccccc3n(C(=O)c3ccc(OC(F)(F)F)cc3)c2n1 +c1cncc(-c2cc3c(cn2)ncc2ncn(-c4ccc5nc[nH]c5c4)c23)c1 +CCC(=O)Nc1cc(Cl)c(Oc2ccc(O)c(-c3ccc(C(C)=O)cc3)c2)c(Cl)c1 +CC1(C#N)CCC(O)CC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +COC1CCN(c2ccc3c(c2)OCC2C(CNC(=O)c4ccc(Cl)s4)OC(=O)N32)C(=O)C1 +Cc1ccc(S(=O)(=O)Nc2nc(-c3ccccc3)cs2)cc1 +CC1(NC(=O)NC(C(=O)N2CC3C(C2C(=O)NC(CC2CC2)C(=O)C(N)=O)C3(C)C)C(C)(C)C)CC1 +O=C1NC(=O)c2cc(SCc3ccc(Cl)cc3)ccc21 +COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C)c(C)c2)cc(Cl)c1O +CN1CC2(CNC(=O)c3c2[nH]c2c3CCc3cnc(-c4cccc(F)c4)cc3-2)C1 +Cc1cc(C)c(O)c(C(CCCCCC(=O)O)c2ccc(F)cc2)c1C +Nc1nc(O)c2c(n1)NCC(CCc1cccc(C(=O)NC(CCC(=O)O)C(=O)O)c1)S2 +O=CC(Cc1c[nH]c2ccccc12)NC(=O)C1CCCCC1 +CCOc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2ccccc2C)CC1 +COc1cc(-c2c[nH]nc2C(F)(F)F)ccc1C(=O)NCc1c(F)cccc1Cl +N#Cc1cccc(OCCCN2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)c1 +CC(CNS(=O)(=O)C(C)C)C1CCC(c2ccc(C#N)cc2)CC1 +O=S1(=O)N(Cc2ccccc2)C(COc2ccccc2)C(O)C(O)C(COc2ccccc2)N1Cc1ccccc1 +Cn1cncc1C(OCc1ccc(C#N)cn1)c1ccc(C#N)c(-c2ccccc2C(F)(F)F)c1 +Cc1nnc(NC(=O)c2ccc(S(=O)(=O)N(C)Cc3ccccc3)cc2)o1 +O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3cccc(C(F)(F)F)c3)cc2)cc1 +COc1cc(NC(=O)c2cc(-c3ccc4c(c3)OCO4)on2)cc(OC)c1OC +CN1C2CC(NC(=O)c3nn(C)c4ccccc34)CC1CN(Cc1ccccc1)C2 +CC(C)Oc1ccc(Br)c(CC2CCN(CCc3cc4c(cc3Cl)OCCO4)CC2)c1 +c1ccc(-c2cc(-c3ccccc3)n3c2CCC3)cc1 +COC1CCC2(CC1)Cc1ccc(CCC3CC3)cc1C21N=C(N)N(CC2CCOCC2)C1=O +Cc1c(O)cccc1C(=O)NC(Cc1cccs1)C(O)CN1CC2CCCCC2CC1C(=O)NC(C)(C)C +CN1C(=O)N(c2ccc(C#Cc3cccc(F)c3)cn2)C2CCCC21 +O=C(O)c1cc(-c2ccccc2)c2ccc(OCc3c(Cl)cccc3Cl)cc2c1 +COc1cc(C(=O)c2sc(-c3ccc(C(C)(C)C)cc3)nc2N)cc(OC)c1OC +Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2[nH]ccc2n1 +Cc1noc(C)c1-c1ccc2c(c1)nc(CCc1ccccc1)n2CC(=O)N1CCOCC1 +O=C(Nc1ccccc1)Nc1cccc(S(=O)(=O)CCCN2CCOCC2)c1 +CCOC(=O)C1CCCN(C(=O)C(=O)c2c[nH]c3ccccc23)C1 +Oc1nsc(C2CCNCC2)c1Cc1ccc2ccccc2c1Br +COc1ccccc1-c1nnc2ccc(-c3ocnc3-c3ccc(F)cc3)cn12 +NS(=O)(=O)c1ccc(C(=O)NCC(=O)NCC(=O)NC(CC(=O)O)C(=O)O)cc1 +Cc1ccc(O)c(CNCC23CC4CC(CC(C4)C2)C3)c1 +O=C(O)c1cccc2[nH]c(-c3c(F)c(F)c(-c4ccc(F)cc4)c(F)c3F)nc12 +NC(N)=NC(=O)N1Cc2c(-c3ccc(F)cc3F)ccc(Cl)c2C(F)C1 +CC(=O)c1nc(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)n2ccccc12 +N#Cc1c(C(=O)NN2CC3CCCC3C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +CCCN(CC1CCC1)C(=O)c1cc(Cl)cc(OCCCON=C(N)N)c1 +Cc1cccc(Cn2cc(C(=N)S)c3c(N)ncnc32)c1 +Cc1c(C)c2ccc(OCCCN(C)Cc3ccccc3)cc2oc1=O +CC(C)(Cc1ccc(NC(=O)CCCNC(=N)N)cc1)NCC(O)c1ccc(O)c2c1OCC(=O)N2 +CC(C)(C)c1ccc(Cn2c(=N)n(CC(=O)c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)c3ccccc32)cc1 +Nc1ncnc2c1ncn2C1OC(CNS(=O)(=O)NC(=O)c2ccccc2O)C(O)C1O +COC(C)c1cn(C2=NCC(=O)N3CCc4c(cccc4C4CC4)C3=C2)cn1 +O=C(NCC#Cc1ccc2ncnc(-c3ccccc3)c2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +O=C(c1ccc(-c2oc3ncnc(NCC4CCCO4)c3c2-c2ccccc2)cc1)N1CCOCC1 +COC(=O)c1ccccc1C1CCC(CNc2nccc(C)c2NC(=O)CC#N)CC1 +O=C(NS(=O)(=O)C1CC1)c1cc(C2CC2)c(OCC2CCC3CC3C2)cc1F +CSc1nc2c(c(-c3ccc(N(Cc4cccnc4)C(=O)c4ccc(O)cc4O)cc3)n1)CCC2 +O=C(CCCCCNC(=O)NC1CCCCC1)NC(Cc1ccccc1)C(=O)O +O=C(O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(C4CC4)cc3)nc2)C1=O +O=C(Nc1cccc(Cc2nnc(O)c3ccccc23)c1)C(F)(F)F +COc1ccc(C(=O)N2CCN(C(=NC#N)Nc3ccccc3C)CC2c2ccccc2)cc1OC +Cn1cc(-c2cc(-c3cccc(F)c3)ccc2OCC2CC2)c2cc[nH]c2c1=O +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2ccccc2)c(Br)c1 +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)N)c1 +CCOc1ccc2cc(-c3nn(C4CCCCC4)c(N)c3C(N)=O)cnc2c1 +CSC(=S)N1CC2(CCCCC2)COC1=Nc1ccc(C#N)c2ccccc12 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1cccc(F)c1)CC2 +C[N+]1(CCCC(=O)Nc2ccc3c(c2)C(=O)c2cccc4ccnc-3c24)CCCC1 +NC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4ccccc4)c(F)cc3F)cc1CC2 +Cc1ccc(C)c(C(=O)NC(C)C(=O)N2CCN(CCCOc3ccc(-c4noc(CC5CCCC5)n4)c(F)c3)CC2)c1 +CN1C(=N)NC(CC2CC2)(c2cccc(-c3cccc(Cl)c3)c2)C1=O +Cc1cc(-c2cc(F)c(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)cc2F)ccn1 +CCN(CC)CCNC(=O)Nc1nc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(C)cc4)c3)cn2n1 +COc1ccc(C=C2c3ccccc3C(=O)c3ccccc32)c(OC)c1O +O=C(Nc1ccc(Cl)cc1)c1cc(F)ccc1NC(=O)c1sc2ccccc2c1Cl +CN(C)c1cccc2c(S(=O)(=O)NCCCNc3ccnc4cc(Cl)ccc34)cccc12 +CCCCCCCCCCOc1ccc(OCC(=O)COc2cccc(OCC(=O)O)c2)cc1 +CN(C)c1ccc(NC(=O)NC2C3CCN(CC3)C2Cc2cccnc2)cc1 +CCOc1cc(COc2ccc3c(c2)NCCN(C(C)C(=O)NO)S3(=O)=O)cc(OCC)c1 +Cc1c(C(=O)CS(=O)(=O)c2ccccc2)sc2ccccc12 +COc1ccc(-c2nc(COc3ccc(OCC(=O)O)c(C)c3)oc2-c2ccc(OC(F)(F)F)cc2)cn1 +CC(C)OC(=O)N1CCC(Oc2ncnc(N3CCc4cc(S(C)(=O)=O)ccc43)n2)CC1 +O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CCC(C(=O)Nc1ccc(-c2ccccc2)cn1)n1nnc(-c2ccncc2)c1-c1ccccc1 +OCC1OC(n2ccc3c(-c4cccs4)ncnc32)C(O)C1O +O=C(Nc1cccc(N2CCN(CCCCNS(=O)(=O)CC3CCCCC3)CC2)c1)C1CC1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCCC(C)(C)NS(C)(=O)=O +CN1CCCC1c1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1 +Cc1nc(NCc2cccc(OC(F)(F)F)c2)nc(-n2ccnc2C)c1[N+](=O)[O-] +CCCCCCCCC(O)C=Cc1cccc(CC(O)c2cccc(C(=O)O)c2)n1 +CN(Cc1cccc(O)c1)C(=O)c1ccc(-c2cccc(N(C)C)c2)s1 +CC(=O)Nc1ccc2nc(Nc3c(C)cccc3Cl)c3cncn3c2c1 +COc1ccc(C2CC2COc2nc(N)nc(NCc3nnc(C)s3)c2F)nc1 +CCC(C)C(CC(=O)O)NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 +C=C1CC2C(CCC3(C)C(c4cncc(F)c4)=CCC23)C2(C)C=CC(=O)C=C12 +COc1cc2c(cc1NS(=O)(=O)c1ccccc1)cc(C)c(=O)n2C +CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(Cl)cc2)nc(N)n1 +O=C(NC1CCC1)C1SC(n2cnc3c(NCc4cccc(I)c4)ncnc32)C(O)C1O +N#Cc1ccc(-c2n[nH]c3cc(OC(F)(F)F)ccc23)cc1 +Cc1ccc(C)c(S(=O)(=O)Nc2onc(C)c2Br)c1 +NC(CC(=O)N1CCSC1C(=O)NCc1ccc2c(c1)OCC(C(=O)O)O2)Cc1cc(F)c(F)cc1F +O=C1N(c2ccc3c(c2)OC(F)(F)O3)CCN1c1cnccc1C1CC1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3cccc(C(F)(F)F)c3)cc2)C(=O)C(C)C)c1 +Cc1ccccc1OC1CCN(c2nc(Cl)cn(C)c2=O)CC1 +OC1CCN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)CC1 +COc1ccc(C(=O)C2CCN(CC(=O)N(Cc3nc4c(c(=O)[nH]3)COCC4)CC(F)F)CC2)cc1 +c1ccc(CCCNC2CCCCN(CCOC(c3ccccc3)c3ccccc3)C2)cc1 +N#Cc1cccc(-c2cnc(C(=O)CCc3ccc(-c4ccccc4)cc3)o2)n1 +Cc1cc(Nc2ccccn2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +O=C(N1CCN(Cc2ccc3ccccc3c2)CC1)n1cc(I)cn1 +COCCN1CC2C(C1)C2c1cc(-c2cnc(N)c(OC(F)F)c2)nc(C2CC2)n1 +CCCCCn1nc(C(=O)NC(C(N)=O)C(C)C)c2ccccc21 +N=C(N)c1cccc(CN2CCC(NS(=O)(=O)c3ccc(-c4cccnc4)s3)C2=O)c1 +CS(=O)(=O)c1ccc(Oc2cc(OC3CCOC3)cc(C(=O)Nc3nccs3)c2)cc1 +CC1CCCCC1Oc1nc(N)c2c(=O)ccn(CC3CC(O)C(O)C3)c2n1 +Cc1ccc(-c2csc(=N)n2CC(=O)N2CCN(C)CC2)cc1 +CCOc1nc2c(n1Cc1ccc(OC)c(Cl)c1)C(=O)N(CC)C1=NC3CCCC3N12 +COc1cc(-c2ccc3c(c2)Nc2ccccc2NC3=O)ccc1[N+](=O)[O-] +CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)nn1-c1ccccc1 +CN(CC(CCN1CCC2(CCc3ccccc32)CC1)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 +CC(C)C(CO)NCc1nc(-c2cccc(S(=O)(=O)N3CCCCC3)c2)ccc1F +CC(C)COc1ccc(-c2n[nH]c(-c3ccncc3)n2)cc1C#N +Cc1nc(C)c(COc2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)o1 +Nc1ncnc2c1c1c(Cl)cccc1n2C1OC(CO)C(O)C1O +Cc1ccc(COc2ccc3nc(C4CCCCC4C(=O)O)n(Cc4ccc(OC(F)(F)F)c(Cl)c4)c3c2)nc1 +O=C(NC1CC1)c1ccc(Nc2nc(Nc3ccc(O)cc3)ncc2F)cc1 +Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccccc1S(=O)(=O)N1CCCCC1 +CC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCC2C(O)c1cccc2ccccc12 +O=C(Nc1cccc(-c2ccn[nH]2)c1)C(Cc1ccccc1)NCc1cscn1 +CC12CCC(Cc3ccccc3)C(=O)N1C(C(=O)NC(CCCN=C(N)N)C(=O)c1nccs1)CS2 +CCCC1C(C#N)=C(N)Oc2[nH]nc(C(C)(C)C)c21 +Nc1cccc(Nc2nc(NCCO)nc(NCCc3ccc(Nc4nc(NCCO)nc(Nc5ccc(Cl)cc5)n4)cc3)n2)c1 +O=C(c1cc(=O)c2cc(O)ccc2[nH]1)N1CCC(Cc2ccccc2)CC1 +CC(C)N(c1ccc(Nc2ncc3cnn(C4CCCCCC4)c3n2)cc1)S(C)(=O)=O +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)cc(-c3cccc(C#N)c3)c2C)cc1 +N#Cc1ccc(Oc2ccnc3cc(-c4cnn(C5CCNCC5)c4)ccc23)cc1 +CC(c1ccc(-c2ccc(C(=O)O)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +CN1CCC(Nc2ccc3nnc(-c4cccc(C(F)(F)F)c4)n3n2)CC1 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+COc1ccc(-n2nnnc2C)cc1COC1CCCNC1c1ccccc1 +O=c1cc(N2CCCCC2)oc2c(-c3cc(-c4ccsc4)ccn3)cccc12 +Cc1nn(C)c(C)c1NS(=O)(=O)c1c(F)cc(-c2ccnc(N3CCNCC3)c2)cc1F +O=C(O)C1C(CC2CCNCC2)C(=O)N1C(=O)N1CCN(C(=O)CCCCCc2ccccc2)CC1 +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(NC2CCOCC2)nc1C1CCCC1 +Cc1ccc(F)c(-c2nc(C(=O)Nc3cnccc3C3CC(C)C(O)C(N)C3)ccc2F)c1F +c1ccc2cc(Cn3cc[n+](Cc4ccc5ccccc5c4)c3)ccc2c1 +CCCCCc1cc2cc(C(=O)NCCc3ccc(F)cc3)c(=O)n(C)c2c(O)c1OC +COC(=O)C1Cc2c([nH]c3ccccc23)C2(CCC(c3ccccc3)(N(C)C)CC2)N1 +N#Cc1cccc(Oc2cc(N3CCC(Oc4ncc(F)c(N)n4)CC3)ncn2)c1 +O=C(c1ccc(C(=O)N2CCC(N3CCCC3)CC2)c(Oc2ccccc2)c1)N1CCC(N2CCCC2)CC1 +CC(C)(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)c(F)c2)c(F)c1 +CCCNC(=O)C1=CC(C)(C)Oc2ccc([N+](=O)[O-])cc21 +CN1CCN(C(=O)Cn2c(-c3ccccc3)c(C3CCCCC3)c3ccc(C(=O)O)cc32)CC1 +COc1ccc(OCCOC(=O)C2CCCCN2S(=O)(=O)c2ccc3ncsc3c2)cc1OC +CCCN1C(S)=NC(C)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1 +C=CCC1CC2C(CCC3(S(=O)(=O)c4ccc(C(F)(F)F)cc4)c4c(F)ccc(F)c4OCC23)NS1(=O)=O 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+CCN1CC=C(C2=Cc3ccccc3Cc3ccccc32)CC1 +NC(=O)COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c(-c3ccsc3)nn(CCC3CC3)c1=O)N2 +CNc1nc(NCc2ccc(F)cc2)n2nc(-c3ccco3)nc2n1 +COc1cc2c(Nc3ncc(Oc4cccc(F)c4)s3)ncnc2cc1OCCCN1CCC(CO)CC1 +COC(=O)c1cc2cc(S(C)(=O)=O)ccc2n1C(=O)c1ccc(Cl)cc1 +Cc1cc2c(-c3ccccn3)c[nH]c2c(C(=O)Nc2ccn(C)n2)n1 +O=c1ccc2ccc(OCCCCOc3c4ccoc4cc4oc(=O)ccc34)cc2o1 +CCOC(=O)C1=C(C)Oc2nc3c(c(N)c2C1c1cc2cccc(OC)c2nc1Cl)CCCC3 +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OCC(CC)(CC)OCc2ccsc2)c1 +OC1CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1 +COc1cc(NC(C)=O)c(Cl)cc1C(=O)Nc1nccs1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1cnc(-c2ncc(C(F)(F)C(F)(F)F)[nH]2)c(Cl)c1 +Cc1ccn2c(CCc3nnc4cc(C)ccn34)nnc2c1 +O=[N+]([O-])c1ccc(C2=NOC3CCCCC23)c(C(F)(F)F)c1 +NCC(NC(=O)c1cc(Br)c(-c2ccnc3[nH]ccc23)s1)c1ccccc1 +CCCCCCSc1nc(-c2ccc(Cl)cc2)nn1C(=O)N(C)c1ccccc1 +CC(C)(C)C(NC(=O)C(CCCc1ccccc1)CC(=O)NO)C(=O)NC1CCCC1 +O=C1C(Cl)=C(c2ccccc2)C(=O)N1c1ccc(Cl)c(Cl)c1 +O=C(CCC1=CCN(Cc2ccc(C(F)(F)F)cc2)C1=O)NO +O=C(Cn1nnc(-c2ccccc2C(F)(F)F)c1-c1ccccc1)Nc1ccc(-c2ccccc2)cn1 +C(=C(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1)c1ccccc1 +CCc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3c2ccc(Cl)c3F)ccc1OCCN1C(=O)CCC1=O +Nc1ncc(-c2cc(C3CC4CC(C3)CN(C3COC3)C4)nc(C3CC3)n2)cc1OC(F)F +Cc1cc(-n2ncc(=O)[nH]c2=O)cc(Cl)c1Oc1ccc(O)c(S(=O)(=O)N2CCCCC2)c1 +Cc1ccc(C(=O)Nc2cc(N3CCCN(C)CC3)cc(C(F)(F)F)c2)cc1Nc1ncnc2ccc(N3CCOCC3)nc12 +CCCCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc2c(ccn2-c2ccccc2-c2nnn[nH]2)c1 +COc1ccc(S(=O)(=O)N(Cc2cccnc2)c2c(C)cc(N(C)C)cc2C(=O)NO)cc1 +CCN(CC)CCOc1ccc2c(c1)C1(CCNCC1)c1[nH]c3ccccc3c1C2=O +CCn1nc(Cc2ccccc2)cc1C1CCN(CC2CN(C(C(=O)O)C3CCC3)CC2c2ccccc2)CC1 +CC(C)N1CCN(C(=O)OC2CCN(c3ccc(=O)n(C)n3)CC2)CC1 +O=C(Nc1cccc(C#Cc2ccc3nccn3n2)c1)c1cccc(C(F)(F)F)c1 +CCCCCN=C(N)Cc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)N1CCN(C(=O)C(C)N)CC1 +O=C(O)CCNC(=O)c1cccc(C(=O)NCCC2CCNCC2)c1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)c1sc2ncccc2c1-c1ccc(Cl)cc1 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+COC(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccc(Cl)cc3)ncc12 +O=C(O)c1ccccc1-c1ccc(CN2CCC(CNC(=O)c3c4n(c5ccccc35)CCCO4)CC2)cc1 +CC1c2nnc(-c3nc(C(F)(F)F)ns3)n2CCN1C(=O)c1ccc(F)cc1 +Cc1c(C(=O)c2csc3ccccc23)c2ccccc2n1CCN1CCOCC1 +CN1CCC23c4c5ccc(O)c4OC2c2ncc(-c4ccc(Cl)cc4)cc2CC3(OCc2ccccc2)C1C5 +CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(C(=O)NC)cc3)sc12 +COc1cnc2c(NCc3nnc4ccc(-c5cnc(C)s5)nn34)ccnc2c1 +CC(C)(CC(=O)N1CCSC1)NCC(=O)N1CC(F)CC1C#N +CNc1ncnc2ccc(C#CCNC(=O)c3cc(OC)nn(Cc4ccc(F)c(F)c4)c3=O)cc12 +C#CCOc1cnc(C(=O)Nc2ccc(F)c(C3(CF)N=C(N)OC4CC43)c2)cn1 +N#Cc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(F)c3)cn2CCN2CCCC2)CC1 +O=C1CCc2c(Oc3ccc4c(c3)CC(NC(=O)c3cc(-c5cnc[nH]5)cc(C(F)(F)F)c3)CC4)ccnc2N1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCN(c3nc(Cl)c(C(F)(F)F)cc3Cl)CC1)C(=O)C2 +COc1cccc(Nc2cncc(-c3cc4c(cnc5cc(OC)c(OC)cc54)c(N)n3)c2)c1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C(C)C)c2cc1OC +COc1ccc(Oc2ccc(C3(N4CCN(CCO)CC4)C(=O)NC(=O)NC3=O)cc2)cc1 +COCCCn1c(CN2C(=O)C(=NOCCC3CCCCC3)c3ccccc32)nc2ccccc21 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+COc1ccc2c(=O)c(C=CC(=O)Nc3cccc(Cl)c3)coc2c1 +COc1ccc(-c2nc(CNC(=O)CSC)sc2-c2ccc(OC)cc2)cc1 +CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccn3)cc2)cc1)C(=O)CCC1CCCC1 +COc1ccc2[nH]cc3nc(-c4ccon4)nc-3c2c1 +Nc1nc2c(c(=O)n(CC3CC3)c(=O)n2CC2CC2)n1S(=O)(=O)c1ccccc1 +C=C1CCC(O)CC1=CC=C1CCCC2(C)C1CCC2C(C)(O)CCCC(C)C +CC(C)(C)C(=O)OCC(CNC(=O)Cc1cc(Cl)c(O)c(Cl)c1)Cc1ccc(C(C)(C)C)cc1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1cc(Cl)cc(Cl)c1OC +CCC(F)(F)c1nc2nc(C)cc(Nc3ccc(S(F)(F)(F)(F)F)cc3)n2n1 +CCOC(O)=C1C(COCCN2CCN(Cc3ccc(Cl)cc3)CC2)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +CN(CCC#N)c1ccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +CCC(=O)c1ccc2c(c1)sc(=O)n2CCCN1CCCCC1 +CC1CN(C(=O)c2ccccc2)CCN1S(=O)(=O)c1c[nH]c2c(-n3ccnc3)ncc(F)c12 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncc(OC4CC4)cc3F)C2)cc1 +CC1(C)OC1CCC(=O)Nc1cccnc1C(=O)Nc1nccs1 +c1cc(Nc2ncnc3[nH]cnc23)cc(-c2nc3ccccc3s2)c1 +O=C(NCc1ccc(S(=O)(=O)c2ccc(N3CCOCC3)nc2)cc1)c1cnc2[nH]ncc2c1 +O=C(c1ccccc1)N1CCC(C(=O)N2CCC(Oc3ccccc3Cl)CC2)CC1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCC(F)(F)CO)ncc23)ccn1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc2cc[nH]c2c1 +O=C(Nc1cc2ccc(-c3ccncc3Cl)cc2cn1)C1CC1 +O=S(=O)(Nc1nccs1)c1ccc2c(-c3ccc(C(F)(F)F)cc3Cl)nccc2c1 +NC(CNc1nc(-c2ccncc2)nc2sc3c(c12)CCC1(C3)OCCO1)Cc1ccccc1 +C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(CN(OC)C(=O)CC)c(F)c2F)c(F)c1 +Cc1nc(-c2ccc(S(N)(=O)=O)cc2)c(-c2ccc(Cl)cc2)s1 +COc1ccc(-c2cc(N3CCOCC3)cc(=O)o2)cc1 +COc1cc(CN(CC2CC2C(=O)O)C(C)c2ccc3c(c2)CCO3)ccc1OCCN1C(=O)CCC1=O +CCCN1CCc2cc(F)cc3c2C1Cc1ccc(O)c(O)c1-3 +CCOC(=O)N1CCC(C(NS(=O)(=O)c2ccc(-c3ccc(OC)cc3)cc2)C(=O)O)CC1 +CCn1c(S)nnc1Cc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +COc1ccc(S(=O)(=O)N2CCN(C(=O)N(C)Cc3ccccc3)CC2C(=O)NO)cc1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C=Cc1ccc(CN2CCOCC2)cc1 +Cn1cc(-c2cccc(C#N)c2)c2sc(C(=N)NC3CCS(=O)(=O)CC3)cc2c1=O +COc1ccc(C)cc1N1CCN(CCn2cnc3sc4c(c3c2=O)CCN(C)C4)CC1 +CCCCC(CC)C(=O)OCC1(CO)CC(=Cc2ccc(C(F)(F)F)cc2)C(=O)O1 +CCOC(O)=C1C(COCc2cc(O)nc(CO)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +O=C1CCc2cc3cc(c2N1)OCCCCOC1CC(CO)N(C1)c1cc(n2ncc(Cl)c2n1)N3 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+O=C(C=Cc1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C2(F)F)NS(=O)(=O)c1cccs1 +Cc1csc(CNc2ncnc3ccc(-c4ccc5c(c4)OCO5)cc23)c1 +Nc1c(F)c(NCCNc2ccccn2)cc2c1c(=O)c(C(=O)O)cn2C1CC1 +CC12CCN(C(=O)C3CCCN3S(=O)(=O)c3ccccc3)C(Cc3ccccc31)C2(C)C +CCCN(c1ncc(C)c(-c2ccc(OC)cc2OC)n1)C(C1CC1)C1CC1 +CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1 +Cc1ccc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)cn1 +Cn1nccc1C(O)c1ncc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)s1 +COCC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +c1ccc(-c2csc3[nH]nc(N4CC5CC4CC5OCCN4CCCC4)c23)cc1 +Cc1ccccc1-c1nc(C(F)(F)F)cn1-c1ccc(S(N)(=O)=O)cc1 +COc1cc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCCC2)ccc1CNS(C)(=O)=O +CC(C)(C)n1nnnc1C(NCCCNc1ccnc2cc(Cl)ccc12)c1ccc(Cl)cc1 +OCC1OC(c2ccc(Cl)c(Cn3nc4ccccn4c3=S)c2)C(O)C(O)C1O +CCOc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)C)n1)CCN2 +Cc1ccc(CC(=O)NCCCC[N+](C)(C)CCNC(=O)c2nc(Cl)c(N)nc2N)cc1 +O=C1CCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)Nc1ccc(C(F)(F)F)cc1)CC2 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+CCn1c(=O)c2nc(-c3ccc(S(=O)(=O)N4CCSCC4)cc3)[nH]c2n(CC)c1=O +CC(C)(C)OC(=O)N1CCC(NC(=O)NCc2cn(-c3ccccc3)c3cc(Cl)ccc3c2=O)CC1 +CC1CN(C(=O)N2Cc3c(NC(=O)c4ccccn4)n[nH]c3C2(C)C)C(C)CN1CCC1CCOCC1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NC(C)c3cccc(Cl)c3F)CC3CC32)c2cnccc12 +CC=CCn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc21 +Cc1cc(F)ccc1C(=C(C=CC(O)CC(O)CC(=O)O)c1nnnn1C)c1ccc(F)cc1C +COc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)cc1 +CCCc1cnc(N2CCC(C3Cc4c(ccc(C5=CCN(S(=O)(=O)CCC)CC5)c4F)O3)CC2)nc1 +CC(=O)NC(C)c1ccc(C2CN(c3ncnc(OCC4CC4(F)F)c3F)C2)cc1 +CN(Cc1ccccn1)c1ccc(C#N)cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(C#N)cc12 +CCCc1nc(CC)c(C(=O)OC)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)C2CC2)cc1 +CCC1CNCCN1c1c(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)cnn1C +CCc1cc(-c2ncnc(CC)c2C#Cc2ccc(N)nc2)ccn1 +O=C(NNc1ncnc2sc3c(c12)CCC3)c1ccccn1 +COc1cc(OC)cc(N(Cc2ccco2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +COc1cc2c(cc1OC)C1CC(O)C(CC(C)C)CN1CC2 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1Nc1ccc(OCCO)cc1CC2 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+COc1cc(-c2cc(C)cc(C)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +NC(=NN=Cc1c[nH]c2ccc(O)cc12)NCCc1ccc(Cl)c(Cl)c1 +CC(C)(CNS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1)c1ccc(C(=O)O)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(N4CCOC(C)(C)C4)c3F)C2)cc1 +CCN1C(=O)CCCc2cc(NC(=O)c3cc(OC(C)c4c(Cl)ccc(F)c4Cl)c[nH]c3=O)ccc21 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCN(S(C)(=O)=O)CC2 +CCn1nc(-c2ccc(C#N)cc2)cc1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2ccccc2)CC1 +CN1CCN(CC(=O)Nc2ccc3c(c2)CC2CCC(C3)C2NS(=O)(=O)c2ccc(Cl)s2)CC1 +CC(C)C(O)C1CCC(N2CC(NC(=O)CNc3nccc4ncc(C(F)(F)F)cc34)C2)CC1 +O=C(c1cccs1)N(c1c(Cl)cccc1Cl)C1CCN(Cc2ccccc2)CC1 +O=C1CC(C(=O)O)Oc2c(COc3ccc(OCc4ccc5ccccc5n4)cc3)cccc21 +CC(C)CCn1c(Cn2nnc3ccccc32)nc2ccccc21 +CCC(N)C(=O)NC(C(=O)N1CCCC1C(=O)NC(c1ccccc1)c1ccccc1)C(C)C +CCc1c(C)c2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n(C2CCCC2)c1=O +CSc1sc(-c2cc[nH]n2)c2c1C(=O)NC1(CCCC1)C2 +Cc1ccc2c(OCCN3CCN(Cc4cc(F)c5c(c4)N(C)C(=O)CO5)CC3)cccc2n1 +CCOP(=O)(CC)c1ccc(Nc2cc(-c3ccccc3OC)ncn2)cc1 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+O=C1Nc2cc(C(=O)C3CCCN3)ccc2C1=C(Nc1ccc(CN2CCCCC2)cc1)c1ccccc1 +CCCN1Cc2c(c3cc(OC)c(OC)cc3c3cc(OC)c(OC)cc23)C(O)C1 +CC1Cc2c(ccc(F)c2F)N1C(=O)Cc1nc(N2CCOCC2)c(F)c(=S)[nH]1 +Cc1nc2nc(-c3ccc(CN4CCC(c5n[nH]c(-c6cnccn6)n5)CC4)cc3)c(-c3ccc(F)cc3F)cn2n1 +CC(C)(COc1ncc(-c2ccc(-c3ncc(C(F)(F)F)[nH]3)c(Cl)c2)cc1F)C(=O)O +CS(=O)(=O)N1CCC(Nc2ncc(C(=O)c3c(F)cccc3F)c(N)n2)CC1 +c1cc(-c2ccc(OCCCN3CCCCC3)cc2)ccc1CCCN1CCCCC1 +O=C(NCCCCCCNc1ccnc2cc(Cl)ccc12)NC1C(=O)N(C2CCCCC2)C1C=Cc1ccccc1 +Cc1nc(NC2CCCc3cc(N)ccc32)cc(-c2ccc3ncsc3c2)n1 +COc1ccc(Cn2cnc3c(N(C)C)nc(C(F)(F)F)nc32)cc1C +NC(=O)c1ccc(F)c2c1CC(NCC1CCc3[nH]c4ccc(F)cc4c3C1)CO2 +CNC(=O)c1ccc(-c2cnc3ncc(Cc4ccc5ncccc5c4)n3n2)cc1C +CCCCS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)NC(c1c(O)c3cccnc3n(CCC(C)C)c1=O)=N2 +CNCc1cc(F)ccc1Oc1ccc(-c2ccccc2)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccc(CN5CCCC5)cc4)nc23)N1 +CC(C)N(C(=O)CN1C=CN(c2ccccc2)C(=O)C(Cc2n[nH]c3ccccc23)C1=O)c1ccc(O)cc1 +N#Cc1ccnc(Nc2cc(C3(C#N)CCOCC3)cc(N3CCC(F)(F)C3)n2)c1 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+O=C(O)Cc1ccc(Nc2nc(-c3ccccc3)nc3c2CCC3)cc1 +COc1cc(CC2(O)c3ccccc3C3=NCCN32)cc(OC)c1OC +N#Cc1ncc2nc1OCCCCCOc1cc(OCc3ccncc3)c(Cl)cc1NC(=O)N2 +COc1ccc(Nc2nc(N)n(-c3ccccc3Cl)n2)cc1OC +CCC(CN)C(C)Oc1cccc2ccc(-c3nnc4ccccn34)nc12 +CCN(CCc1cc(-c2ccc(F)cn2)on1)C(=O)c1cc(C)ccc1-n1nccn1 +N#Cc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)N3CCN(C(=O)C4CCCO4)CC3)cc1)C2 +COc1ccc(-c2[nH]c(=O)nc3nc(Nc4ccc(S(N)(=O)=O)cc4)sc23)cc1 +CC1=NN(c2ccccc2)C(=S)C1=CNc1ccccn1 +CON=C(COCC12CC3CC(CC(C3)C1)C2)C(CCN1CCC(O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1 +Clc1ccc(-n2cc(CCCN3CCN(c4ccccc4)CC3)cn2)cc1 +Cc1nn(-c2ccnn2C)c2c1C(c1ccc(Cl)cc1)N(c1cc(C)c(=O)n(C)c1)C2=O +CC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1ccc(N)nc1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CCCCC3(C)C)ns2)n1 +Nc1ccc(-c2nn(C3CCCC3)c3ncnc(N)c23)cc1O +COc1ccc2cc(S(=O)(=O)NN(Cc3cccc(C(=N)N)c3)C(=O)N3CCC(C)CC3)ccc2c1 +NCCCCCCCCNC(=O)C1OC(n2cnc3c(N)ncnc32)C(O)C1O +Cc1cc(C(F)(F)F)ccc1Nc1nc(Sc2ccccc2)nc2c1CCN(c1ncccc1C(F)(F)F)CC2 +NS(=O)(=O)c1ccc(CCNC(=O)CCCNC(=O)NCc2ccccc2)cc1 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+CC1CN(C(=O)OC2(C(F)(F)F)COC2)CCN1c1ncc(OCc2ccc(CS(C)(=O)=O)cc2F)cn1 +O=S(=O)(c1ccc(F)cc1)N1CC=C(CCc2ccc(F)cc2F)CC1 +NC(=O)c1ncc(NC2CCCCC2N)cc1C#Cc1ccccc1 +Nc1nccc(Oc2ccc(NC(=O)C3CCCN(c4ccccc4)S3(=O)=O)cc2F)c1Cl +Cc1ccc(CC(COC(=O)C(C)(C)C)CN(O)C(S)=NCc2ccc(NS(C)(=O)=O)cc2F)cc1C +Cc1ccc(OCC2CCC(C(=O)N3CCCC3C#N)N2)cc1 +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(Cl)c3)n3c2CCOCC3)cc(C)n1 +COc1cc(OCCCON=C(N)N)cc(OS(=O)(=O)c2ccccc2S(C)(=O)=O)c1 +Nc1onc(-c2ccc(F)cc2)c1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C1NC(=O)c2c1ccc1c2c2cc(O)ccc2n1CCC(=O)N1CCOCC1 +COc1cc(OCc2csc(N3CCN(C)C(C)C3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +O=C(CCCCCSc1nc(Cc2ccccc2)cc(=O)[nH]1)NO +CC12CCC3C(CC(=CCO)C4CC(=NOCCN)CCC43C)C1CCC2=O +CCOC(=O)c1c(CSc2cc(Cl)cc(Cl)c2)[nH]c2c1cc(O)c1ccccc12 +Cc1c(NC2CCOCC2)cccc1C(=O)NCC(O)CN1CCc2ccccc2C1 +O=C1Nc2ccc3ncsc3c2C1=CNc1ccc2c(c1)CS(=O)(=O)C2 +O=C(NCCC(c1ccccc1)c1ccccc1)c1ccc(=O)[nH]c1 +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)O +COc1cc(OCc2cccc(C3=CCOCC3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=S(=O)(c1ccc(F)cc1)C1(F)CCN(CCc2ccc(F)cc2F)CC1 +O=C(Nc1ccccc1)Nc1cccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)c1 +CC(C)c1ccc(C=C2SC(=O)N(CC(=O)NCCCn3ccnc3)C2=O)cc1 +N#Cc1ccc2cc(-c3cc4cc(CN5CCC(CN)CC5)ccc4[nH]3)c(=O)[nH]c2c1 +C#CC1CCC(C#N)N1C(=O)CNC1(C)CCN(c2ccc(C#N)cn2)CC1 +Nc1ncnn2c(C(O)C3CCOCC3)cc(-c3cc(F)c(CO)c(F)c3)c12 +O=C(NO)c1cc(CS(=O)(=O)c2ccc(Cl)cc2)on1 +O=C(Nc1ccc(Oc2ccnc3ncc(=O)[nH]c23)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(OCCNCCCO)ncc1Cl +Cc1ncnc2c1c1sccc1n2C1OC(CO)C(O)C1O +COc1ccc(C2=[N+]([O-])c3cc([N+](=O)[O-])ccc3C2=O)cc1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCC(O)CO)no2)cc1C#N +CC(Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1)C(F)(F)F +CC(C)CC(NC(=O)c1ccc(N2CCC(CNCC(O)c3ccc(O)c(NS(C)(=O)=O)c3)CC2)cc1)C(=O)O +CCOc1cc(-c2ccccc2)nc2c(F)c(-c3nc(C4CC(C)(O)C4)n4ccnc(N)c34)ccc12 +CN1CCN(C2CC(c3ccc(F)cc3)c3ccc(Cl)cc32)CC12CCCCC2 +CC(C)C(NC(=O)Cn1c(-c2ccccc2Cl)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F +COc1ccc(Cn2cnc(N)c3nc(C(C)(C)O)nc2-3)cc1OC1CCCC1 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+O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1c2c2cccc3c2n1CCNC3 +O=C(c1cnc2ccc(-c3ccc(O)c(Cl)c3)cc2c1NC1CCC(N2CCCC2)CC1)C1CC1 +Cc1cc(-n2nc(Cc3cc(F)cc(C(F)(F)F)c3)nc2C)ccc1C(N)=O +Cc1cc(F)ccc1Nc1nc(N(C)c2ccccc2)c2cccc(OCCCN(C)C)c2n1 +CC(C)CC(NC(=O)COc1c(Cl)cc(Cl)c2ccccc12)C(=O)NC1CC(=O)OC1O +COc1c(Cl)cc(C(C)(C)C)cc1NC(=O)C(=O)c1ccc(OCCN2CCOCC2)c2ccccc12 +CCOc1ccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cc1F +COc1nc(NCCc2ccc(F)cc2)nc(-c2cccc(C(C)=O)c2F)n1 +COc1cc(-c2ccc3ncc(C(=O)C(C)C)c(Nc4ccc(CN(C)C)cc4)c3c2)cc(Cl)c1O +CC(C)(O)C#Cc1cc2c(cc1F)C1CC(C1)n1c-2nc(C(N)=O)c1-c1nc(C2CC2)no1 +O=C(c1cc(-c2cnn[nH]2)ccn1)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1 +CCCn1c(=O)c2[nH]c(-c3cc(OCC4CC(=O)N(c5ccc(F)cc5)C4)no3)nc2n(CCC)c1=O +COc1cc2ncnc(N3CCN(C(S)=NCc4ccco4)CC3)c2cc1OC +COC(=O)CC1Cc2ccccc2C(CCN2CCCCC2)O1 +Cc1ccc(C(CN2CCC2)N2CCN(c3ncnc(N)c3-c3cn[nH]c3)CC2)c(F)c1F +CC(CSC(CCc1ccccc1[N+](=O)[O-])c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O +CCN(CC)CCOc1ccc(N(C)C(=O)c2ccc(-c3ccccc3)cc2)cc1OC +CC(Nc1nccc(NCCc2ccccc2)n1)c1ccccc1 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+CCCN1C(=O)OCC1Cc1cc(CC2CS(=O)(=O)CC(NCc3cccc(C(C)C)c3)C2O)ccc1O +CC#CCN(C)c1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)OC(C)(C)C)CC2)cc1 +NC(Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2CC1C(=O)NCc1nc2ccccc2[nH]1 +CCS(=O)(=O)CCOc1cc(C)c(-c2cccc(CNc3ccc(CCC(=O)O)c(F)c3)c2)c(C)c1 +COc1cc(C(C)=O)ccc1OCCCN1CCC(CC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +COc1cc2c(CN3C(=O)CSC3=O)cnc(C(=O)c3cccc(OC(C)C)c3)c2cc1OC +Cc1ccc(S(=O)(=O)N(CCn2cc(COCCOCCOCCOCCOCCF)nn2)C(C(=O)NO)C(C)C)cc1 +O=C(NC(c1c[nH]c2ccccc12)c1nnc(CCc2ccccc2)n1-c1ccccc1)c1ccccn1 +CCCn1c(=O)c2nc(-c3cc(NC(=O)Cc4cccc(F)c4)nn3C)[nH]c2n(CCC)c1=O +COc1ccc(CNC(=O)c2cc3cccc(N4CCN(CCc5ccccn5)CC4)c3o2)cc1 +Cc1ccc(C(=O)n2ccc([N+](=O)[O-])n2)cc1 +O=C(CCCN1CCCC1=O)NCC1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COC(=O)CCCNC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 +COc1cccc(NC(=O)Cc2cc(Nc3ncnc4cc(OCCCN5CCC(CO)CC5)c(OC)cc34)[nH]n2)c1 +CCN(Cc1c(C(F)(F)F)nc2n(-c3c(C)cc(C)cc3C)c3ccccc3n12)CC1CC1 +CCN1CCN(Cc2ccc(C(=O)Nc3cccc(-c4ccc5nc(NC(=O)C6CC6)sc5n4)c3)cc2C(F)(F)F)CC1 +O=C1N(c2ccc(C#Cc3cccnc3)cn2)CC2CCCCN12 +NC(Cc1ccc(-c2ccc(F)cc2)cc1)C(=O)N1CCSC1 +CC(C)(C)c1ccc(Sc2ccc(NC3=NCCN3)cc2)cc1 +CC(=O)NCCC1CCN(C(=O)C(CCCN=C(N)N)NS(=O)(=O)c2cccc3c2NCC(C)C3)CC1 +O=C(NC1CCCCC1)c1cn(Cc2ccccc2F)c2nc(Cl)ccc2c1=O +C=CC(=O)Nc1cccc(-c2nn(C(C)C)c3ncnc(N)c23)c1 +CC(C)(CCN1CCOCC1)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 +C1=CCOCc2cc(ccc2OCCN2CCCC2)Nc2nccc(n2)-c2coc(c2)COC1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1ccc(-c2cccc(C(F)(F)F)n2)cn1 +CN1CCN(CCCOC(=O)Nc2cccc(Cn3nc(-n4ccc5ccc(F)cc54)ccc3=O)c2)CC1 +O=C(O)CN(Cc1ccc(Oc2ccccc2)cc1)S(=O)(=O)c1c(Cl)cccc1Cl +Cc1nc(-c2nc3c(s2)CN(C(=O)c2ccncc2)CC3)cs1 +Cc1cc(N=S2(=O)CCC2)cc2ncnc(Nc3ccc(Cl)cc3OC(C)C(=O)NC(C)C(F)(F)F)c12 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1ccccc1 +COc1ccc(Cl)c(N2CC3CN(c4ncc(-c5nnn(CC(=O)O)n5)s4)CC3C2)c1 +Cc1cc(Nc2ccc(CCC3COC(N)=N3)cc2)c2ncccc2c1 +Cc1c(C(=O)Nc2cccc(C(F)(F)F)c2)cc(-c2ccccc2)n1CCCN1CCOCC1 +Cc1ccc(C(=O)Nc2cc(-c3cc4c([nH]3)C3(CCN(C)CC3)CNC4=O)ccn2)cc1C +Nc1n[n+]([O-])c2cc(C(F)(F)F)ccc2[n+]1[O-] +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3C4CCC(CC4)C3N(CC3CCCC3)C1=O)N2 +CC(C)S(=O)(=O)NCC1CCC(NCCN2CCOc3cc(F)c(F)cc32)CC1 +C=CCN1CCN(C(=Nc2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)CC1 +Cc1ccc(C(C)O)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +NS(=O)(=O)c1nnc(NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)s1 +C=CC(=O)NCCCCC(NC(=O)OCc1ccccc1)C(=O)N1CCN(C)CC1 +O=C1CC(c2ccccc2)c2cccc3c2N1Cc1c(-c2noc(C4CC4)n2)ncn1-3 +Nc1cccc(-c2cnc3[nH]cc(-c4cccc(NC(=O)Nc5ccc(C(F)(F)F)cc5F)c4)c3c2)c1 +COc1ccc2[nH]c3c(C(=O)NCCN(C)C)ccc4c3c(nn4CCN3CCCC3)c2c1 +CC1CCC(C(=O)Nc2ccccc2)CN1c1cc(-c2ccc3c(N)n[nH]c3c2)nc(N)n1 +COC(=O)c1c(CN2CCN(S(C)(=O)=O)CC2)c(=O)c2ccc(F)cc2n1-c1ccccc1 +CCn1nnc(C2OC(n3cnc4c(NCc5cccc(Br)c5)ncnc43)C(O)C2O)n1 +CCC(=O)N1CCC(NC(=O)Nc2ccc(Br)cc2)CC1 +COc1ccc(CN2CC3CCN(S(=O)(=O)c4ccc(Cl)s4)CC3Oc3c(NC(=O)C4CC4)cccc3C2=O)cc1 +O=C(O)c1ccc2c(c1)C(=CCc1cccnc1)c1ccccc1CO2 +O=c1[nH]nc(CCc2ccc(OC(F)(F)F)cc2)cc1O +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccc(Nc3ncccn3)cc2o1 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+Cc1cc(-n2ccnc2C)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +COc1cccc(C)c1OCC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12 +[C-]#[N+]c1coc(C(=O)N2CC3CNCC(C3)C2)c1 +COc1cc(F)c(-c2cccc(C(CC(=O)O)c3ncc(C)s3)c2)cc1F +CC1CCCC(C)N1C(=S)SSC(=S)N1C(C)CCCC1C +Cc1cccc(-c2cn(-c3cc(C(=O)O)ccn3)cc2C#N)c1 +c1ccc(OCCCCOc2ccc(-c3cc4cc(C5=NCCN5)ccc4o3)cc2)cc1 +CS(=O)(=O)N1CCOC(CNc2nc(Cc3ccccc3)cc(Nc3cc(-c4ccco4)[nH]n3)n2)C1 +CCc1nc2ccc(Cl)cn2c1C(=O)NCc1ccc(N2CCN(c3ccc(F)cc3)CC2)cc1 +CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CC(C(F)(F)F)(C(F)(F)F)C2)cc1 +COc1ccc(CC(=O)Nc2nc3nn(CCCc4ccccc4)cc3c3nc(-c4ccco4)nn23)cc1 +CCN1c2ncc(CCc3ccc4ccccc4c3)cc2C(=O)N(C)c2ccc(F)nc21 +Cn1ccc(-c2cc(Nc3ccc(-n4cnc(N5CCOCC5)n4)cc3)ncc2F)n1 +CN(Cc1cccc(F)c1)C(=O)c1cc2c(Cc3cccc(Cl)c3)n[nH]c2cc1O +CC12CCC3C4CCC(=O)C=C4CCC3C1CC(I)C2O +CC1OC(c2ccccc2)=NC1CN1CCN(c2ccccc2)CC1 +CS(=O)(=O)c1cc(Br)c2c(c1)c1c(n2Cc2cccc(Cl)c2)C(CC(=O)O)CC1 +O=C(Cc1cccc(NC(=O)c2cccc(COc3ccccc3)n2)n1)NO +Cc1csc2nc(C(C)NC(=O)C=CC(=O)c3cccc([N+](=O)[O-])c3)oc(=O)c12 +Nc1ncc(-c2cc(N3CC4CC3CS4)nc(N3CCC(F)C3)n2)cc1OC(F)F +COc1cc2cncc(Cc3ccc4c(c3)oc(=O)n4C)c2cc1OC +Cc1ccc(C2CC2COc2nc(C)ncc2-c2ccn(CC(F)(F)F)c(=O)c2)nc1 +CN1CCN(Cc2ccc(CCCc3ccccc3)cc2O)CC1 +CCOC(Cc1ccc(OC(=O)Cc2ccc(NC(=O)OC(C)(C)C)cc2)c(Cc2ccccc2)c1)C(=O)O +COc1ccc2c3c(ccc2c1)OC(c1cc(F)c(F)cc1F)C(N)C3 +Cn1ccc(-c2cc(Nc3ccc(N4CCOCC4)cc3)ncc2Cl)n1 +CCOC(=O)c1nnn(-c2ccc([N+](=O)[O-])cc2[N+](=O)[O-])c1C +O=C1NCC(=O)N(Cc2ccc(Oc3cccc(Cl)c3)cc2)C1Cc1c[nH]c2ccccc12 +O=c1n(CCN2CCC(=C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)nc2n1CCCCC2 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(F)cc1 +O=C(c1cc(-c2cncnc2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2)N1CCCC1 +COC(=O)CCCCCCC(=O)Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 +CC(=O)Oc1ccccc1C(=O)OCOC(=O)c1ccc(CC(CO[N+](=O)[O-])O[N+](=O)[O-])cc1 +Clc1ccc2c(NC3CCN(Cc4ccccc4)CC3)c3c(nc2c1)CCCC3 +O=C1c2ccccc2C2C(C(=O)O)C(C(=O)O)C2c2ccc(-c3cccc4ccccc34)cc21 +CC(C)(C)OC(=O)NC(C(=O)N1CCCC1C(=O)NCc1ccc(C(=N)NN)s1)C(c1ccccc1)c1ccccc1 +CC(C)CCCC(C)C1CCC2C(OC(=O)c3cccc(O)c3)CCCC12C +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2nc(CN3CCN(c4ccccc4)CC3)ccc2c1 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc2c(-c3cccc(C#N)c3)ncn2c1 +COCCS(=O)(=O)C(C(=O)NCc1cc(C(C)C)no1)c1nc2ccc(-c3ccccc3)cc2s1 +CC(=O)OCN(C)N=Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1 +CC12Cn3cnc(-c4ccc(F)cc4)c3C=C1CCCC2C(C)(O)c1cccnc1 +O=C(NC1CC(F)(F)C1)NC(Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1 +COc1cc(-c2nc3cccnc3n(CC(=O)O)c2=O)cc(O)c1OC +CC(=O)NC(C)c1ccc(C2CN(c3ccc4c(c3)OCCCO4)C2)cc1 +O=C(Nc1ccc(Cl)cc1)NC1CCC(Oc2ccc(C(=O)O)cc2)CC1 +O=C(NN=Cc1ccc(O)c2ccccc12)c1ccc(O)c(F)c1 +COc1cc(Cl)cc(-c2cc(-c3ccc4cc(OC)ccc4c3)n(C(C)c3ccc(C(=O)NCCC(=O)O)cc3)n2)c1 +Cc1ccc(C(=O)NC2C(CO)OC(n3cnc4c(NC5CCCC5)ncnc43)C2O)cc1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)c1ccc(-c2ccccc2)cn1 +CCCc1c(Cl)cc(O)c(OC)c1C(=O)NCC1CCCN1CC +COc1ccc2nc(NC(=O)CN3CCN(Cc4ccc(C(F)(F)F)cc4)CC3)sc2c1 +O=C(C=CC1=C(C(=O)O)N2C(=O)C(=Cc3ccccn3)C2S(=O)(=O)C1)NC1CC1 +CC(Nc1c(-c2c(F)cc(OCCCN3CCCCC3)cc2F)c(Cl)nc2ncnn12)C(F)(F)F +Cc1cc2c(-c3nc4c(c(C5(S(C)(=O)=O)CC5)n3)OCC3COCCN43)cccc2[nH]1 +Nc1nccc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)c1Cl +C=CCc1c(C)nc(-c2ccc(C)cc2)nc1Nc1ccc(C(=O)O)cc1 +OB(O)c1ccccc1CN1CCC(Oc2ccc(C(F)(F)F)cn2)CC1 +CCCCCCCCCCCCCCC(CC(=O)O)C(=O)NC(C(=O)NC)C(C)(C)C +CC(=O)c1ccccc1-c1nnc(N2CCC(N3CCCCC3)CC2)s1 +CCN(CC)c1ccc(OC)c2nc(-c3c(Cl)cc(COC)cc3OC)c(C)cc12 +COCC1CCCN1CCn1ncc2cc(-n3ccc(OCc4ccccc4)cc3=O)ccc21 +C=CCNc1ccnc2sc3c(=O)n(-c4ccc(OC)cc4)cnc3c12 +CCCCCn1cc(C(=O)NCc2ccc(Cl)c(Cl)c2)c(=O)c2ccc(Br)cc21 +CC(=O)CNC(CCC(=O)NC(CSC(=O)N(O)c1ccc(Cl)cc1)C(=O)NCC(=O)O)C(=O)O +O=C(Nc1ccc(Cl)cc1B(O)O)c1ccc(Oc2ccc(C(F)(F)F)cc2)nc1 +CN(CCCCCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1 +Cc1cc(-c2ncc(CNC(=O)c3ccc4c5ccccc5n(C)c4c3)cc2F)ccn1 +N#Cc1ccc(-c2ccc3c(c2)C2(CCCCC2)C(S)=N3)o1 +CS(=O)(=O)N1CCN(Cc2cnc3c(Cn4cnc5cc(-c6ccc(Cl)cc6)sc5c4=O)cccc3c2)CC1 +NC(=O)c1cn(C(CO)CCn2ccc3ccc(NC(=O)CCCCc4ccccc4)cc32)cn1 +CCNc1cc2c(cc1Cl)NC(=O)Nc1cnc(C#N)c(n1)OCCCCO2 +COC(=O)C1(Cc2ccc(OC)cc2)CC(=O)OC1(C)c1ccccc1 +CC(C)c1noc(N)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +COc1nc(Nc2ccc(C#N)cc2)nc(Nc2c(C)cc(C)cc2Br)n1 +O=C(CO)N1CCCC12CCN(c1ncnc3[nH]ccc13)C2 +CCC(NC(=O)c1cc(C(=O)N2CCN(C)CC2c2ccccc2)n2c1COCC2)c1ccccc1 +CCC(CC)Nc1c2c(nc3c(-c4ccc(OC)cc4Cl)c(C)nn13)OCC2 +Nc1cnc(-c2ccc(-c3ccccc3-c3cnc(N)cn3)cc2F)cn1 +CC(C)(C)OC(=O)C1N2C(=O)C(=Cc3ccc([N+](=O)[O-])cc3)C2S(=O)(=O)C1(C)C +O=c1c(-c2ccccc2)c(SCc2ccncc2)oc2cc(OCc3ccc(-c4ccccc4)cc3)ccc12 +COc1cc2c(CO)cc3c4cc5c(cc4ncc3c2cc1OC)OCO5 +Oc1c(CNCCCCCCCCCCCCNc2c3c(nc4ccccc24)CCCC3)cc(Cl)c2cccnc12 +CC(CO)Nc1cc(NS(=O)(=O)c2cn(C)cn2)nc(SCc2cccc(Cl)c2F)n1 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(CN5CCN(C)CC5)ccn34)c12 +Fc1ccccc1NC(=S)Nc1ccccc1SSc1ccccc1NC(=S)Nc1ccccc1F +CCC1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CO +CC(=O)N1CCC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +COc1ccc(-c2cccc(NC3=NCCN3)c2C)c(OC)c1 +CN(C)CC(O)COc1ccc(Nc2cc(N(CCC#N)c3cc(Cl)ccc3Cl)ncn2)cc1 +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(OC)cc3)CC21C +CN(CCNC(CO)c1cc(Cl)cc(Cl)c1)c1nc2nc(Cl)ccc2[nH]1 +CN(C)CCn1cc(S(=O)(=O)c2ccc(F)cc2)c2cccnc21 +CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCCN)CC4)c2)CC1 +Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCCC1CCN(CCCc2ccccc2)CC1 +Cn1ncc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)NC1CCCC1O +O=C(NCCCCN1CCN2c3ccccc3Cc3ccccc3C2C1)C1CCCCC1 +COCCOc1cnc(Nc2cnc(OC)c(NS(C)(=O)=O)c2)c(-c2nc(C)nc(N)n2)c1 +CCCC(=O)C1CCN(C(=O)n2sc3c(ccc[n+]3[O-])c2=O)CC1 +CC1CC2(C)CC(=O)C1C1C(=O)N(OCCCN3CCN(c4cccc(Cl)c4)CC3)C(=O)C12 +C=CCc1c(OC)nc2nc(C(=O)c3ccccc3)cn2c1CC +COC(=O)CCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(C)=O)c1 +O=c1[nH]c(NC2CCCC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +O=S(=O)(c1ccc(-n2ccnn2)cc1)C1(F)CCN(CCc2ccc(F)cc2F)CC1 +CC(C)(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1 +CC(CCc1ccc(C2=CCCC2)cc1)(C(=O)NO)S(C)(=O)=O +O=C(O)c1cc2ccccc2n1CCCOc1cccc2ccccc12 +CC(=O)CCCCCC(NC(=O)C1CCN(C)C1)C(=O)NCCc1c(-c2ccccc2)[nH]c2ccccc12 +COc1cc(C2c3cc4c(cc3C(CC(=O)N3CCC(C)CC3)C3COC(=O)C23)OCO4)cc(OC)c1O 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+COc1cccc(OC)c1OCCNCc1cc2ccccc2[nH]1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(F)cc2c1OCOC2 +O=C(O)Cc1sc(Nc2ccccc2)nc1-c1ccccc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1CCC(N)CC(C)(O)C1 +COC(=Cc1cc(F)c(OC)c(F)c1)C(=O)c1cc(OC)c(OC)c(OC)c1 +O=C(O)CCc1ccc(COc2ccccc2)cc1C(=O)NCCc1ccccc1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c([N+](=O)[O-])cccc3nc2-1 +O=C(O)CN1C(=O)C(=Cc2cccc(Oc3ccccc3)c2)SC1=S +COCCS(=O)(=O)NC1CC(N(C)c2ncnc3[nH]ccc23)C1 +COc1cc(OCCNCc2ccc(F)cc2)c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1 +COc1cc(-c2nc(C)n(-c3ccc(F)cc3)n2)ccc1-n1cnc(C)c1 +CCN1CCCC1CN1C(=O)c2cccc3cc4ccccc4c(c23)C1=O +CC(C)CC(NC(=O)C1(c2ccccc2)CC1CN1CCC2(C)c3cc(O)ccc3CC1C2C)C(=O)NCCCCN=C(N)N +CCCc1nc(N)c(Cc2ccc3oc4ccccc4c3c2)c2cc(OC)c(OC)cc12 +COc1cc(Cn2c(=O)ccc3cccc(OC)c32)cc(N2CCNCC2)c1 +Nc1ncc(-c2cn3cc(C(=O)NCCN4CCOCC4)nc3c(N3CCOCC3)n2)cn1 +CC(C)=CCCC(C)=CCCCCCCC(P(=O)(O)O)P(=O)(O)O +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)C2CCCC2)c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC(=O)c3ccccc3C1)CC2 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+NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3CCCS3(=O)=O)cc2n1 +Cn1ncc(NC(=O)c2csc(-n3ncc4ccccc43)n2)c1C1CCC(N)C(F)CO1 +NCCNC(=O)NC(=O)C1CCCN1C(=O)C(CC1CCCC1)CN(O)C=O +CCN(CC)CCCCCCCNc1ccc2c3c(nn2CCN(CC)CC)-c2ccccc2C(=O)c13 +COc1cc2c(cc1OC)C(=O)N1C=C(c3cccc(C)c3)CC1C=N2 +COc1ccc(-c2cc(-c3c(C)oc4c(OC)c5occc5c(OC)c4c3=O)[nH]c(=N)c2C#N)cc1OC +Cc1ccncc1-c1cc(F)c2c(c1)CCc1nnc(C)n1-2 +CC1(C)CC(O)(C(F)(F)F)C(Nc2cccc3[nH]c(=O)ccc23)c2ccc(F)c(O)c21 +Cc1ccc(-n2nccn2)c(C(=O)N2CCOCC2Cc2cccc(-n3cncn3)c2)c1 +c1ccc(C(OCCN2CCN(CCOC(c3ccccc3)c3ccccc3)CC2)c2ccccc2)cc1 +ClCCN(CCCl)CCCCOc1ccc(Nc2c3ccccc3nc3c(OCCN(CCCl)CCCl)cccc23)cc1 +COC(=O)C(C)NP(=O)(OCC1C=CC(n2cc(C)c(=O)[nH]c2=O)O1)Oc1cccc(Cl)c1 +CCc1nnc(C(Cc2ccccc2)NS(=O)(=O)c2ccc(Cl)cc2)n1C +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2cccc(=O)[nH]2)cn1C(C)C +CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cccc1OC +CCc1nc(-c2ncn3c2CN=C(c2ccccc2)c2c(F)cccc2-3)no1 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccc3c(c2)CCCC3)c1)C(F)(F)F +CC(=O)Nc1ccc(C#Cc2ccc(NC(C)=O)cc2)cc1 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+COc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N(C)C)cc4c3)n2)c1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)c1cn(CCO)cc(-c2ccc(F)cc2)c1=O +COc1cc(OC)cc(N2CCN(C(=O)c3onc(C)c3-c3ccc(F)cc3)CC2)c1 +COc1ccc2c(c1)C(=NNC(=O)c1cnn(-c3ccc(S(N)(=O)=O)cc3)c1-c1ccccc1)C(=O)N2 +CCCCCC12CCC(COc3cc(F)c(C(=O)NS(=O)(=O)N(C)C)cc3Cl)(CC1)CC2 +CC1CCN(C(=O)c2ccc3nc[nH]c3c2)C2Cc3ccccc3C12 +COC(=O)c1cccc(-c2cnc(C(=O)C3COc4cc(Oc5ccccc5)ccc4C3)o2)n1 +O=C(O)CCCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O +C=CC=CC(C)C1OC(=O)C=CC=CC(C)C(O)CC(O)CCC(C)C(O)C(C)CC(C)CCC(O)C1C +CC(C)Oc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3ccccc31)CC2 +Cc1nc(N2CC3CN(C(=O)c4ccccc4-n4nccn4)CC3C2)ncc1F +Cc1c(O)cccc1C(=O)NC(Cc1ccccc1)C(O)C(=O)N1CSCC1C(=O)NC(C)(C)C +CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)c2C1 +O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(c1)CCN2C1CN(CCF)C1 +COc1ccc(C2(c3ccc(OC)cc3)C(c3ccccc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1 +CC(C)CC(NC(=O)c1cnccn1)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1 +O=C(CN1CCN(c2ccnc(NCCc3ccc(Cl)cc3)n2)CC1)N(Cc1ccccc1)Cc1ccncc1 +CCC1CCCC(C2(OC(=O)N3CCC(N4CCCCC4)CC3)CC2)N1S(=O)(=O)c1ccc(F)c(F)c1 +CN1CCc2c([nH]c3ccccc23)Cc2[nH]c3ccccc3c2CC1 +O=C(c1ccc(C(=O)N2CCCC3CCCCC32)cc1)N1CCCc2ccccc21 +Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)n1C1CCCCC1 +Cc1cnc(NC(=O)c2cc(Sc3nncn3C)ccc2N)s1 +CCN1CCCC(n2c(-c3cccc(C=CC(=O)NO)c3)nc(C)c2-c2ccccc2)C1 +CNS(=O)(=O)c1ccc(NC(=O)Nc2ncccc2OCc2ccccc2)cc1 +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(C(C)=O)cn3)CC2)CC1c1ccc(Cl)cc1 +O=C(O)Cn1c(=O)c(-c2ccc(O)cc2O)nc2ccc(Br)cc21 +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(N3CC4C5CCC(C)(O5)C4C3)c2cn1)c1ccc(F)cc1 +CCCS(=O)(=O)Nc1ccc(F)c(-c2cc3cnccc3cn2)c1F +O=C(NCCc1ccc(OCCN2CCCC2)c(Br)c1)c1cccc(C(F)(F)F)n1 +COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 +CC(O)c1nc2cnc3[nH]ccc3c2n1C1CCC(CCC#N)CC1 +O=C(Cc1ccc(C(F)(F)F)cc1C(F)(F)F)NC1N=C(C2CC2)c2ccccc2N(CC(F)(F)F)C1=O +CCc1nc2c(C)cc(C)nc2n1Cc1ccc2c(c1)CCN2C(C(=O)OC)c1ccccc1 +COCC(NC(=O)Nc1cc2[nH]nc(Nc3ccccc3)c2cn1)c1ccc(F)cc1 +CCc1csc(C(Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)CNC(=O)OC)n1 +O=C(CCc1ccc(OCc2ccccc2)cc1)c1nc2ncccc2o1 +COc1cc(Cn2c(CCc3ccccc3)nc3cc(CCC(=O)NO)ccc32)cc(OC)c1OC +C=CC(=O)Nc1ccccc1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1 +O=C(Nc1nc(-c2ccccc2)cs1)C1CCCCN1C(=O)N1CCS(=O)(=O)CC1 +Cc1noc(C)c1C(=O)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CCCCc1nc(CN2CCN(c3ccccn3)CC2)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +N#Cc1cc(NCCCn2ccnc2)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +COCc1cccc(-c2cnc3ccc(NC(=O)NC(C)CCCc4ccccc4)nc3n2)c1 +CCCC(NC(=O)C1(NC(=O)c2ccc(OC(F)(F)F)cc2)CCCCC1)C(=O)c1nnc(-c2ccccc2)o1 +O=C1NC(=O)C2(CCN(CCC3CC(=O)c4ccccc4C3)CC2)N1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(O)(CNC(=O)Cc1ccccn1)C2 +O=C(OC1CCN(Cc2ccc(F)cc2)C1)C(O)(c1ccccc1)c1ccccc1 +Cc1cn(-c2ccc3n(c2=O)CCN(C(C)C2CCC(c4ccc(C(F)(F)F)cc4Cl)O2)C3=O)cn1 +CC1=NN(c2nnn[nH]2)C(=O)C1=Cc1cc(Cl)c(O)c(Cl)c1 +FC(F)(F)c1cc(COCC2(c3ccccc3)CCN(Cc3ncon3)CC2)cc(C(F)(F)F)c1 +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3cccc4[nH]cc(C)c34)nc(N3CCCC(O)C3)c2C1 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+CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)C4CCCN4CC(C)C)ncn3)cccc2s1 +CC(C1C(O)CC2(C)C3CCC4C5(C)COC(C(C)(C)F)=NC5CCC45CC35C(=O)CC12C)N(C)C +CS(=O)(=O)C1CCc2c(c(-c3ccc(C(F)(F)F)c(SCCO)c3)nn2CCCN2CCC(N3CCCC3=O)CC2)C1 +Cc1cnccc1N1CCN(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CC1 +O=C(NC1CCNC1)c1ccc2[nH]c(-c3cc4ccccc4nc3O)cc2c1 +Cc1cccnc1C1CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +N=C(N)c1cccc(Oc2ccc(N)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +O=C(O)C=NOC(c1ccc(OCc2nc(-c3ccccc3)cs2)cc1)C1CCCCC1 +COc1cc(-c2cc3cc(C(C)N(O)C(C)=O)ccc3o2)cc(OC)c1OC +CCn1c(C=CC=C2N(C)c3ccccc3C2(C)C)[n+](CCCOC(C)=O)c2nc3ccccc3nc21 +COc1cc(OC)c2c(C(=O)C=C(O)C(=O)O)cn(Cc3ccc(F)cc3)c2c1 +Cc1nc(NC2CCCc3ccccc32)cc(-c2ccc3ncsc3c2)n1 +CCNCCNc1cc(-c2ccc(C(F)(F)F)cc2)c(C#N)c2nc3cccc(Cl)c3n12 +CCNc1ncc(C(=O)OCC)c2nc(-c3ccco3)nn12 +CC(C)c1ccc(-n2ncc(Cl)c(Oc3ccc(CO)cc3)c2=O)cc1 +CC(=O)c1ccc(-c2ccc(C(=O)NCCCCN3CCc4ccc(OS(=O)(=O)C(F)(F)F)cc4C3)cc2)cc1 +Cc1ccc2c(N3CCN(CCc4cc(F)c5c(c4)NC(=O)CO5)CC3)cccc2n1 +COc1ccc(-c2noc(CSc3nnc(C)n3-c3cccc(C)c3)n2)cc1 +CS(=O)(=O)c1ccc2c(c1)CCC1(CCCN(C(=O)NC3CC3c3ccccc3)CC1)O2 +CC(C)(CNc1nc(NCCO)nc(Nc2cccc(N)c2)n1)CNc1nc(NCCO)nc(Nc2cccc(N)c2)n1 +Cc1cc(C(N)=O)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(Cl)cc1NC=O +CN(C)CCCN1CCCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)C1 +CCCCCCc1nccn1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +CC(C)CNC(=O)c1cc(-c2cc(F)c(Cl)cc2Cl)n[nH]1 +NC1CCN(C2CCC3(CC2)OOC2(OO3)C3CC4CC(C3)CC2C4)CC1 +COc1ccc(C2=NN(CCNCC(O)c3ccc(O)c(NC=O)c3)C(=O)C3CCCCC23)cc1OC +CCn1cc(-c2cc3c(-c4cc(C#N)cc(N5CCCNCC5)n4)n[nH]c3cn2)cn1 +CC1(C)OC(c2ccnc(N)n2)=C(c2cc(Cl)cc(NS(=O)(=O)c3ccc(F)cc3F)c2F)C1=O +c1ccc2c(c1)NC1CCCCC1=C2NCCCCCCCCNC1CCNC2CCCCC21 +Cc1cccc(C(=O)NC(CC(=O)O)C(=O)CF)c1NC(=O)OCc1ccccc1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4ccc(C(F)(F)F)cn4)CC3)CN(C)C1C2 +N#CC1CC(F)CN1C(=O)CNCCNc1ccc(C(N)=O)cn1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1ccc(F)cc1 +CCCC1(C2CCCC2)Cc2cc(OCCCC(=O)O)c(Cl)c(Cl)c2C1=O +COc1nccc2[nH]nc(-c3cc(C(=O)N(C)C)n(C(C)C)c3)c12 +O=c1c(-c2ccc(F)cc2)c(-c2ccnc(NCc3ccccn3)n2)n2n1CCC2 +Cc1cc(N)nc(CCc2cc(N)cc(CCc3cc(C)cc(N)n3)c2)c1 +NC(=O)c1ccc(NC(=O)c2ccc(-n3ccccc3=O)cc2)c(NC(=O)c2ccc(Br)cc2)c1 +CC(NC(=O)c1cccn1C(C)C)c1c(F)cccc1Cl +CC(C)COc1ccc(S(C)(=O)=O)cc1-c1cn(C)c(=O)c2[nH]ccc12 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc(OC(F)(F)F)cc4)cc3F)ccnc2cc1OCCCN1CCCCC1 +Nc1ncc(CNC(=O)Nc2ccc(S(=O)(=O)c3ccccc3)cc2)cn1 +Cc1ccc(F)cc1C1CC(=NN=C(N)N)c2ccccc2C1 +CCOc1ccc(C(C)=O)cc1NC(=O)c1cc(COC2CCCCO2)cc(C(=O)O)c1 +CCN(CC)CCNC(=O)c1ccc(-c2cnc(N)c(SC(C)c3c(Cl)ccc(F)c3Cl)c2)cc1 +CN(CC=Cc1ccc(Br)cc1)Cc1cccc2cc[nH]c12 +COC(=O)C1(CNC(=O)c2cc(Cl)cc(Cl)c2)CCN(Cc2ccc(C(F)(F)F)cc2)CC1 +Nc1ncnc2c1ncn2C1OC(CNC(=O)COC2=C(c3cccc(Cl)c3)C(=O)OC2)C(O)C1O +CCOc1cc(CN2CCC(NC(=O)c3cncc(C)c3)CC2)cc(OCC)c1-c1ccccc1 +C=CCN(c1cccnc1)C1CCN(CC2CN(C(=O)C3CCCCC3)CC2c2ccccc2)CC1 +Cc1ncc(OCC2(c3ccccc3)CC2C(=O)Nc2ccccn2)c(C)n1 +Cc1cc(C)n(CC(=O)N2CCN(c3scnc3-c3nc4ccccc4[nH]3)CC2)n1 +O=C(O)CCc1ccc(OC2CCN(C(=O)NC3C(c4ccc(F)cc4)C3c3ccc(F)cc3)CC2)cc1 +Cn1cc2cc(-c3n[nH]c4ccc(C(=O)NC5CC(C(F)(F)F)CN(Cc6c(F)cccc6F)C5)cc34)ccc2n1 +c1ccc(Oc2ccc3c(NCCCNCc4ccco4)ccnc3c2)cc1 +Cc1ncc2ccc(Oc3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2n1 +C=CC(=O)Nc1ccc(OC)c(Nc2cc(-c3[nH]c(SC)nc3-c3ccc4ccccc4c3)ccn2)c1 +CC(C)Cc1sc(-c2nccs2)nc1C(=O)NCCCCCC(=O)NO +CCCCCCCCCCCOc1ccccc1CCC(=O)OCc1ccccc1OP(=O)(O)OCC(N)C(=O)O +CC(c1ccccn1)c1c(CCN2CCC2)sc2ccccc12 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)c(-c3ccc(Cl)cc3)cc21 +Nc1nc(=O)c2c(CCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)c[nH]c2[nH]1 +C#CCC1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 +CC(C)n1c(CNC2CCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CN1CN(c2ccccc2)C2(CCN(Cc3csc4ccccc34)CC2)C1=O +COc1ccc(-c2c(O)nc3cc(Cl)c([N+](=O)[O-])cc3c2OCCC2CCCCN2)cc1OC +CC(=O)Nc1nc(C)c(-c2csc(Nc3cccnc3)n2)s1 +CN1C(=O)CN=C(c2ccccc2)c2cc(Cl)c(Cl)cc21 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(N)C5)cn3)n2)s1 +O=C(O)CCCCC=C(c1cccnc1)c1cccc(Br)c1 +O=C1c2c(c(-c3c(F)cccc3F)c3cccnc3c2O)CN1Cc1ccc(F)cc1 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+O=C(Cc1ccccc1)NC(NC(=O)Cc1ccccc1)c1ccc(N2CCCCC2)cc1 +COC(=O)C(C)NC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C +CCc1cc(C)c(-c2nnc(CCOC)[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +O=C(c1ccccc1)N1CC2CC34CCC1C2C31CCN(CC2CC2)C4Cc2ccc(O)cc21 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cnn(-c2ccc(C(F)(F)F)cc2)n1 +O=S(=O)(c1cccc(F)c1)c1cn(CCN2CCCC2)c2ncccc12 +CC1(CF)C=C(C(S)=NCCC#N)c2cc([N+](=O)[O-])ccc2O1 +COCC1OC(=O)c2coc3c2C1(C)C1=CCC2(C)C(=O)CCC2C1C3=O +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)NNC(=O)C(N)=O)cccc2-3)cc1 +CC1COCCN1c1nc(-c2ccc(Nc3nn(C)c(=O)[nH]3)cc2)nc2c1CCN(c1ncccn1)C2 +COc1ccc(C2C(=O)N(c3cc(OC)c(OC)c(OC)c3)C2c2ccc(OC)cc2)cc1 +COc1ccc(C(C(=O)NCCCN2C(C)CCCC2C)c2ccc(OC)c3ccccc23)c2ccccc12 +CN(CCOc1ccc(CC(Nc2ccccc2Oc2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 +O=C(Cc1ccccc1)Nc1nonc1NC(=O)c1ccccc1 +CSc1cc(NC(=O)CCC2OC3OC4(C)CCC5C(C)CCC(C2C)C35OO4)cc(SC)c1 +CSc1ccccc1C(=O)C1CCCN(Cc2cnn(-c3ccccc3)c2)C1 +CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2C)c(F)c1 +CC(C)(C)c1ccc2c(=O)n(-c3cccc(-n4cc(C(N)=O)c(Nc5cnccn5)n4)c3CO)ncc2c1 +Cc1nc(-c2nnc3n2CC(C)N(Cc2cccc(C(F)(F)F)c2Cl)C3=O)cs1 +CC1=NN(c2ccc(C)c(C)c2)C(=O)C1=C(C)NNC(=S)N1CCc2cc(C(=O)N3CCOCC3)ccc21 +O=S1(=O)N(CCC2CNCCO2)c2ccccc2N1c1ccc(F)cc1 +O=C(Nc1ccccc1)c1cc(N2CCN(C(=O)n3nnc4ccccc43)CC2)ccc1[N+](=O)[O-] +CC(CN)CNc1nc2ccc(Cl)cc2c2[nH]c3ccccc3c12 +Cc1ccnc(N2CCC(Oc3ncccc3C3CCOCC3)CC2)c1 +NC(=O)C1CC(NC(=O)C(N)CCCN=C(N)N[N+](=O)[O-])CN1 +COc1ccc(S(=O)(=O)C(CCc2ccc(Oc3ccccc3)cc2)CC(=O)NO)cc1OC1CCCC1 +CC(c1ccc(-c2ccccc2)cc1)C(N)C(=O)NC(c1ccc(Cl)cc1)C(F)(F)F +CN1CCC(N(C)CC2CCN(c3ncnc4scc(-c5ccccc5)c34)C2)C1 +COc1cc(-c2nc(-c3cc(C)nc(C)c3)c3n2CCOCC3)ccc1OC(F)(F)F +COc1ccc(S(=O)(=O)NC2CCC(N3CCC(c4ccccc4OC4CC4)CC3)CC2)cc1OC +CC(C)(C)c1nccn1CC1CC(c2ccccc2)(c2ccccc2)C(=O)O1 +COc1cccc2c1C13CCN(CC4CC4)C(C2)C1(OC)CCC(=O)C3 +COC(O)=C1C(C)=NC(C)=C(C(=O)OCCN2C(=O)c3ccccc3S2(=O)=O)C1c1cccc(Cl)c1Cl +CC(=O)N(C)c1ccc(C(C(=O)N(C)C)C(N)C(=O)N2CCC(F)C2)cc1 +O=C(O)CN1CCN(C(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2ccccc2)CC1 +O=[N+]([O-])c1cc(C(F)(F)F)c(Cl)c([N+](=O)[O-])c1Nc1cc(C(F)(F)F)ccc1Cl +CCn1c(=O)c2c(nc(Cc3cccs3)n2C)n(Cc2ccccc2)c1=O +NC(=O)c1ccc(-c2cc(C(=O)O)c3cnn(Cc4ccncc4)c3n2)cc1 +Cc1ccnc(C2COC(=O)N2c2ccn3ncc(-c4ccc(-c5nc[nH]n5)cc4)c3n2)c1 +O=C(C=Cc1ccc2ccccc2c1)Nc1ccc2c(c1)OCCO2 +O=CC(CC(=O)O)NC(=O)c1ccc(CNS(=O)(=O)c2cccc(C(=O)O)c2)nc1 +CCCC1(CC)Cc2c(CN3CCC4(CC3)CCN(C(=O)c3ccc(N)cn3)CC4)cccc2O1 +CC1CCN2C(=O)c3c(O)c(=O)c(C(=O)NCc4ccc(F)cc4F)cn3CC2O1 +CCc1oc(SCc2cc(N3CCOCC3)cc(NCc3cccc(C)n3)n2)nc1C +CCc1nn2c(-c3ccc(C)cc3OC)cccc2c1N(CC1CC1)CC1CC1 +O=C(Nc1cscc1-c1nc(O)c(O)c(C(=O)O)n1)NS(=O)(=O)c1cccc2ccccc12 +O=C(NC1CCCC1NC(=O)c1ccc2c(Cl)c[nH]c2c1)c1ccc(N2CCCCC2=O)cc1 +Cc1cnc(C(=O)Nc2cccc(C3(C)CCSC(N)=N3)c2)cn1 +Cc1c(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CO2)ccc(F)c1C#N +O=c1c2c(oc(O)c1C(c1cccc(NS(=O)(=O)c3ccc(F)cc3)c1)C1CC1)CCCCCC2 +CCCN(CCC)c1cc(C)nc2c1NC(=O)CN2c1ccc(C#N)cc1Cl +O=c1c2c(oc(O)c1C(c1cccc(NS(=O)(=O)c3ccc(OC(F)(F)F)cc3)c1)C1CC1)CCCCCC2 +CNc1nc(Nc2cnn3c2C(C)N(C)CC3)ncc1C(F)(F)F +CCCCN(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)C(CC(=O)O)c1ccc(Cl)c(F)c1 +CCOC(=O)CN(C(=O)C(CC(=O)NCC1CCCN(C(=N)N)C1)NS(=O)(=O)c1ccc2ccccc2c1)C1CC1 +N=C(Nc1cccc(C2(O)CCN(CCc3cccc(Cl)c3)CC2)c1)c1cccs1 +NC(=O)c1ccc2c(c1)N=C(C=Cc1ccccc1)N(C1CC1)C2 +Cn1c(C(N)=O)cc2c(-c3ccc(NC(=O)C4CCCN4C(=O)OC(C)(C)C)cc3)ncnc21 +CC1CCCN1CCc1ccc(C2=CCC3CN(C(=O)c4cccnc4)CC23)cc1 +CCCCCCCCCCc1cc(NC(=O)Nc2c(C(C)C)cccc2C(C)C)on1 +CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CC4CCNC4C3)c2c1Cl +N#Cc1c(N2CCC(c3cccc(C(F)(F)F)c3)CC2)ccn(CC2CC2)c1=O +COc1ccc(S(=O)(=O)N(Cc2ccc(F)cc2)CC2CCC(C(=O)O)CC2)cc1 +CNC(CC(C)C)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1 +CC(C)(CNC(=O)C1(C#N)CCOCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +Cc1ccc(NCc2ccc(-c3ccc(F)cc3)nc2)cc1 +CCOC(=O)C(Cc1ccccc1)Nc1nc2ccccc2o1 +O=C(Nc1ccc(F)cc1)c1ccc(SCc2ccccc2O)nc1 +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(C5CCN(C)CC5)cc4)c3)c(OC)cc21 +Nc1nc(N)c2nc(CNc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)ccc2n1 +COc1ccccc1CCN(C)c1cc(-c2ccncn2)cc(=O)n1C +CSc1cc(C)nc(SC)c1NC(=O)N(Cc1ccccc1)Cc1cccc(-c2ccnn2C)c1 +CC(C)CC(NC(=O)OCCC1CCCCC1)C(=O)NC(C=O)CC1CCNC1=O +COc1ccc(C(=O)N(CCC2CCCN2C)CC(C)=Cc2ccccc2)cc1C +COc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)ccc1-c1cccc2c1oc1ccccc12 +COc1cccc(OC)c1C1CCC(=O)N1Cc1ccc2oc3ccccc3c2c1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 +O=C(c1ccc([N+](=O)[O-])cc1)c1ccc(Cl)c(Cl)c1 +CCCCCN(CC(O)C(Cc1ccccc1)NC(=O)OCC(C)C(=O)OC)S(=O)(=O)c1ccc(OC)cc1 +CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3cc(C)c(C)cc3n2)c1)C(=O)O +Cn1c(=O)c2nc(-c3cccc4ccccc34)[nH]c2n(C)c1=O +Cc1nn(-c2c(F)cccc2F)cc1CN1CCC2(CC1)OCCc1cc(F)sc12 +Cc1ccc(C(=O)NC2C3CCN(CC3)C2Cc2cccnc2)o1 +COc1ccccc1CNC1C2CCNC1(c1ccccc1)CC=C2C +CCNS(=O)(=O)c1cccc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)c1 +Cc1cccc(C=CC(=O)c2ccc(O)c(N=Nc3ccc(S(N)(=O)=O)cc3)c2)c1 +CC(C)(Cl)CC(=O)c1cc(C(C)(C)C)c2c(c1)C(C)(C)CO2 +Cc1cc(C)c(CNC(=O)c2c(C)n(C(C)c3cnn(C)c3)c3ccccc23)c(=O)[nH]1 +CC(F)(F)c1cccc(N2C(=O)CN(c3cccc(C(F)(F)F)c3)CC2C(=O)NC2CCCC2)c1 +CC1CCN(C(=O)N2CCCC2)CC1N(C)c1ncnc2[nH]ccc12 +COc1ccccc1N1CCN(CCn2c(C)nc3c(sc4ccccc43)c2=O)CC1 +CN(C)C(=O)n1nnnc1CNC(=O)c1cccc(-c2ccccc2)c1 +COc1ccccc1C1CCN(c2[nH]c(=O)[nH]c(=O)c2Cc2ccccc2)CC1 +Cc1cccc(C(=O)c2nccc3c2[nH]c2ccccc23)c1 +O=C(NO)c1cc2ccn(Cc3ccc(F)cc3)c2cn1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C4CC4)nn3)c2)c2cncnc21 +O=C(NCc1ccc(S(=O)(=O)c2cnc(N3CCOCC3)nc2)cn1)c1ccc2nccn2c1 +Cc1cc(C(=O)Nc2ccc(C(F)(F)F)cc2)ccc1-c1ncccc1C(F)(F)F +Cc1ccc(C(=O)N2CCC3(CC2)OCc2cc(C#N)ccc23)cc1NC(=O)c1ccc(N2CCCC2)nc1 +CCOC(=O)N1CCC(Nc2ncc3c(n2)-c2c(c(C(=O)NC)cn2C)CC3)CC1 +NS(=O)(=O)c1ccccc1-c1ccc(C(=O)NCCC(=O)Nc2ccc(Br)cc2)cc1 +CN(C)CCn1cnc(-c2ccc(F)cc2)c1-c1ccc2[nH]ncc2c1 +Cc1nnc(C(C)C)n1C1CCN(C(C)CC(NC(=O)C2CCOCC2)c2ccccc2)CC1 +CC(C)Oc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCN(C)C)CC1 +COc1nn(C)c2ncnc(NS(=O)(=O)c3cccc(Cl)c3Cl)c12 +CCCCNC(=O)Oc1ccc2c(c1Br)c1c(n2C)C(=NC)CC1 +CCN(CC)CCNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C +Nc1ncc(-c2cc(N3CC(N4CCC(F)(F)CC4)C3)nc(N3CCC(F)(F)C3)n2)cc1OC(F)F +COc1cc(C(=O)N2CCC2c2noc(-c3ccccc3OC(F)(F)F)n2)c(-n2nccn2)cc1F +CCc1cc(OCCc2ccc(C(=N)N)c(O)c2)cc(OS(=O)(=O)c2cc(Cl)cc(Cl)c2OC)c1 +N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]c(CO)nc3Cl)c2F)c1 +Cc1nn(CCO)c(C)c1CC(=O)NCc1cccc(Cl)c1C +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5cccc(OC)c5)C4)c3)nc2n(CCC)c1=O +CC(=O)Nc1ccc(-c2csc(-c3ccc(S(=O)(=O)Nc4ccc(CCNCC(O)c5cccnc5)cc4)cc3)n2)cc1 +Cc1ccc(C(=O)NC2CC2)cc1-c1cc2nnc(-c3c(F)cccc3Cl)n2n(C)c1=O +O=C1CCC(C(=O)NC(CCCCCS)C(=O)Nc2cccc(C(F)(F)F)c2)N1 +COC(=O)NC1(c2ccc(N3CCc4c(C(F)(F)F)nn(-c5ccc(OC)cc5)c4C3=O)cc2)CC1 +Cc1cc(OCc2ccccc2)cc(C)c1-c1cccc(COc2ccc(CCC(=O)O)cc2)c1 +COc1c(OCC(O)CN2CCCCC2)ccc2c1N=C(NC(=O)c1cncs1)N1CCN=C21 +CS(=O)(=O)Nc1ccc(S(=O)(=O)N(CCC2CC2)c2sc3ccccc3c2Cl)cc1 +CCCCc1cn(-c2c(C(C)C)cccc2C(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1 +CCC(NC(=O)c1cc(C(=O)NC(C)c2ncccn2)c2n1CCOC2)c1ccccc1 +c1ccc(CN2CCN(CC3COC(C4CCCCC4)(C4CCCCC4)O3)CC2)cc1 +O=C1Nc2ccc(Cl)cc2C(C#Cc2ccncc2)(C2CC2)N1 +Cc1ccc(C(=O)N2C3CCC2C(Nc2cnc(C(F)(F)F)cn2)C3)c(-n2nccn2)n1 +CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 +CN(C)C12CC(NC(=O)CN3CCCCC3)C(C(c3ccccc3)C1)C(c1ccccc1)C2 +CCOCCn1nc(CC)c2nc(N3CCNCC3)nc(Nc3cccc(C)n3)c21 +CON=C(CCN1CCN(c2ccccn2)CC1)c1ccccc1 +N#Cc1cccc2c1C=Cc1ncc(N3CCCCC3)cc1C2O +N#Cc1cncc(N2CCC(S(=O)(=O)c3ccccc3C(F)(F)F)C2)n1 +N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)cn3)o2)cc1 +CC(C)Oc1ccc(N=c2[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2CC2CCCC2)cc1Cl +CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +CC(NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2c(N)cccc2F)cc1 +CCCCC#Cc1ccc(-c2c(C)c(C(=O)NC3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 +COc1ccccc1N1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O +CCCCCCCCCCCCCCCC(=O)Nc1cccc(OP(=O)(O)O)c1 +COc1cccc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(C(=N)N)c2)c1 +CCCC(C)N1CCC(C2NC(CNC(=O)c3ccc4cc(Cl)ccc4c3)CCN(CC(CC)c3ccccc3)C2=O)CC1 +O=C1NC(C(=O)O)Cc2ccc(cc2)OCC=CCOc2ccc(Cl)c1c2 +O=C1C(=O)N(CCc2ccccc2)c2c(Br)cc(Br)cc21 +O=C(C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2)Nc1ccccc1 +CCCCCCCCCCCCCC(=O)OCCCOP(=O)(O)OCC(N)C(=O)O +CC1(C)CNC(=O)c2sc(Nc3ccc(I)cc3Cl)c(C(=O)NCCC(O)CO)c2C1 +COc1ncc(Cl)cc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(Br)cc2)cc1)C(=O)O +COc1ccc2c(c1)C1(Nc3ccccc3-c3nc4ccccc4n31)C(=O)N2 +Cc1ccccc1-c1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2n1 +N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)c2ccncc2F)CC3)c1 +CC1=CC(=O)N(Cc2ccc(F)cc2)S(=O)(=O)O1 +COc1ncc(Cc2cn(CCCC(=O)N3CCN(c4ccc(Cl)cc4)CC3)c(SCc3ccc(F)cc3)nc2=O)cn1 +COCCN(CC(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)c1ccc2oc3ccccc3c2c1 +Cc1ccc2c(OCCN3CCC(Cc4cccc(N5CCN(C)CC5=O)c4)CC3)cccc2n1 +CC(=O)N1CCN(c2cc(-c3cccc(O)c3)nc(N3CCOCC3)n2)CC1 +O=C(CC1CCCC1)Nc1cnc(-c2ccncc2)c(-c2ccco2)n1 +COCC(COc1nc(Oc2ccc3c(c2)COB3O)c(Cl)cc1C#N)OC +COc1cc2ncnc(N3CCN(C(=NCc4ccc(C)cc4)NC#N)CC3)c2cc1OC +COCCOC(=O)C1=C(C)NC2=C(C(=O)CCC2)C1c1ccc(OC)c(OC)c1OC +CN1CCC(C(CCCCC(=O)N2CCC(CNC(=O)c3cc(Cl)cc(Cl)c3)C2)c2ccccc2)CC1 +O=C(O)c1[nH]c(=O)[nH]c(=O)c1CCc1cccc2ccccc12 +Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(Cl)c5)cc(C(F)(F)F)nc34)cn2)cn1 +CNC(=O)c1sc(C(C)(C)C)cc1NC(=O)Nc1ccc(C)cc1 +CCCN(CCC)c1cc(C)nc2c(-c3ncc(C)cc3Cl)c(C)nn12 +COCCC1CN(Cc2c(C)[nH]c(=O)c(I)c2Sc2cc(C)cc(C)c2)CCO1 +CCCCOP(=O)(CCCCC1(C(=O)NCCN2CCOCC2)c2ccccc2-c2ccccc21)OCCCC +CCNC(=O)c1ccc(-n2c(C)nc3cc(C)ccc32)s1 +CCNC(=O)OCc1c(COC(=O)NCC)c(-c2ccc(Cl)cc2)n2c1Cc1ccccc1C2 +CCOC(=O)C(O)=CC(=O)c1cn(Cc2cc(F)ccc2F)c2cccc(OC)c12 +c1ccc2cc3c(Nc4ccc(N5CCCCC5)cc4)ccnc3cc2c1 +Nc1ncc(-c2ccc(-n3cccn3)cc2)cc1C(=O)Nc1ccncc1 +CC12CCC(=O)C=C1CCC1C2CCC2(C)C(c3cccnc3)=CCC12 +COc1cccc(C2OC(CCn3ccc(CC(=O)O)n3)c3cccn3-c3ccc(Cl)cc32)c1OC +COc1nc(-c2ccncc2)nc2c1CN(C(=O)Nc1ccccc1)CC2 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)C1CCCCC1 +CC(C)=CCCC(C)SCCC(C)=CCCC=C(C)CCC=C(C)CCC1OC1(C)C +Clc1ccc(-n2cc(COCCCN3CCN(c4ccccc4)CC3)cn2)cc1 +O=C1CC2(CCN(C(=O)c3cc(-c4ccccc4)nc(-c4ccccc4)c3)CC2)Oc2cc(N3CCCC3)ccc21 +CC(=Cc1ccc(Cl)cc1)S(=O)(=O)Nc1cc(F)ccc1S(N)(=O)=O +CC(=O)NCCc1ccc(C(=O)CCCN2CCC(c3ccc(Cl)cc3)CC2)cc1 +CCC(CO)Nc1nc(Nc2cncnc2)c2ncn(C(C)C)c2n1 +COc1ccc(Cn2c(CC(C)(C)C(=O)O)nc3cc(OCc4ccc5ccccc5n4)ccc32)cc1 +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1cc(-c2ccc(F)cc2)c2ncccc2c1 +COc1ccccc1CNC(=S)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O +Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C(C)C +CC(C)(C)OC(=O)N1CC(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(c2ccccc2)C1 +COC(=O)CCCCCNC(=O)c1ccccc1N=Cc1ccccc1 +O=c1[nH]nc(Cc2ccc(F)c(CNC3CCOCC3)c2)c2c1CCCC2 +Oc1cc(Oc2cccnc2)cc(-c2cccc3[nH]ccc23)c1 +Cc1cccc(C2CC2COc2cc(NCc3ncc(C)s3)c(=O)n(C)n2)n1 +CCOC(=O)Cn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CCC1Cc2cc3c(C(F)(F)F)cc(O)nc3cc2NC1CC +CC(CO)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)c(C(F)(F)F)c3)c2)c2cncnc21 +CC1CN2c3c(cc4c(C(=O)N5CC(F)(F)C5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(C3CCN(C(=O)c4ccon4)CC3)nc21 +Clc1ccc2c(NCCNc3cc(Cl)nc(Cl)n3)ccnc2c1 +CCC1CN(c2nc(N)c(C(=O)NCC(F)(F)F)nc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +N=C(NCCCC(N)C(=O)NC1CCCNC1)N[N+](=O)[O-] +CCCn1c(C2CCN(C)CC2)nc(-c2ccc(Cl)c(Cl)c2)c1-c1ccnc(NC2CC2)n1 +CCCCN1CCN(C(=O)c2ccc(NCc3ccc(-c4cccc(F)c4C(=O)OC)cc3F)nc2)CC1 +CS(=O)(=O)N1CCc2c(-c3cnc(N)nc3)nc(N3CCOCC3)nc21 +COc1ccc2cc1Oc1ccc(cc1)CC1c3c(cc(OC)c(OC)c3Oc3cc4c(cc3OC)CCNC4C2)CCN1C +CCNC(=O)c1ccc(OCc2conc2C2CCC(F)CN2)nc1 +CCn1ncc2c(NCc3ccc(OC)c(Cl)c3)c(C(=O)NCCCCCO)cnc21 +Cc1cc(C)cc(Sc2c(CN3CCOCC3)c(C)[nH]c(=O)c2I)c1 +O=c1n(Cc2ccc(C(F)(F)F)nc2)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)cnn12 +CN1CCC(c2ccc(Cl)cc2)C(COc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1 +CC(C)CN(NC(=O)OC(C)(C)C)c1nccc(C#N)n1 +O=C(Nc1ccc2cc(CN3CCCC3)cnc2c1)c1ccc(-c2ccc(Cl)cc2)cc1 +CNC(=O)Oc1cccc(CN(C)CCCCCCCOc2ccc3c(c2)OC(=Cc2c4ccccc4cc4ccccc24)C3=O)c1 +CN(C(=O)C1(c2ccc(F)cc2)CCC1)C1CCc2c(CC(=O)O)c3cccnc3n2C1 +Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)ns1 +COc1cc2c(N)nc(N3CCN(C(=O)CC(c4ccc(F)cc4)N4CCCCC4)CC3)nc2c(F)c1OC +COC1COCCC1NC1CC2CN(C(=O)OCC(C)(C)C)CC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +NC1CCC(C(=O)Nc2cc3cc[nH]c(=O)c3cc2Cl)C1 +COc1ccc(CNC(=O)c2cccc(NCc3nnc(-c4ccncc4)[nH]3)c2)cc1 +CS(=O)(=O)Oc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 +CC1CCCC(N2CCC(c3c(F)ccc(Cl)c3F)=CC2=O)c2cc(ccn2)-c2ccc(Nc3ncccn3)cc2NC1=O +CCC(CC)(NC(=O)c1ccc(N2CCC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC +Cc1nc(-c2ccc(F)cc2)ncc1C(=O)N(C)c1ccc(CN2CCNC(C)C2)cc1 +CCNC(=O)Nc1cc2c(-c3ccnc(C)c3)ccc(Cn3ccnn3)c2cn1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncc(Cl)cc1C(=O)O +O=C1CCC(=O)N1c1ccc(F)c(S(=O)(=O)Nc2cc(Sc3ncn[nH]3)c(O)c3ccccc23)c1F +COc1ccc2c(c1)CN(C(=O)CCN1CCCCC1c1nnc(Cc3ccccc3)o1)CCS2 +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCNC(=O)C5)ncn4)c3c2)cn1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1ccc(OCC(F)(F)F)cn1 +Cc1nc2ccccn2c1C(=O)NN=Cc1c(-c2ccccc2)no[n+]1[O-] +COc1ccnc(NCCCOc2ccc(CC(CC(=O)NO)NC(=O)c3ccc(OC(C)C)cc3)cc2)c1 +CCN(CC)C(=O)COCC(C)C1CCC(C)C(N(C)c2ncnc3[nH]ccc23)C1 +CNc1nc(NC2(C#N)CCCCC2)nc(-n2cnc(C)n2)n1 +O=C(C=Cc1ccc(Cl)c(Cl)c1)NCCCCCN1CCC(c2c[nH]c3cccc(O)c23)CC1 +NCCCc1cc2c(-c3ccc(Cl)cc3)c[nH]c(=O)c2c2cc(-c3cn[nH]c3)ccc12 +O=S(=O)(c1ccc(C2=CC3N=CN=C(Nc4ccc(OCc5ccccc5)c(Cl)c4)C3S2)cc1)N1CCOCC1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4cnccn4)s3)c2)C(O)C(O)C1O +COc1ccc(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)C(CCC(=O)NCC2CCCCC2)C(=O)NO)cc1 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCC1OCCO1 +N#Cc1ccc(Nc2nc(O)nc(Cc3c(Cl)cccc3Cl)n2)cc1 +COc1ccccc1N1CCN(c2ncnc3c2cnn3C2CCCC2)CC1 +Cc1ccc(C[n+]2cc(-c3ccc(F)cc3)n3c2CCC3)cc1 +CCCN(CCC)C(=O)Cn1c(=O)n2c3c(cc(-c4ccccc4)cc31)CCC2 +COCCOc1cncc(-c2cc3c(cn2)CCc2c-3[nH]c3c2C(=O)NCC3)c1 +Cc1ccc(C(=O)NN=C(Cn2c([N+](=O)[O-])cnc2C)c2ccc(Br)cc2)cc1 +CCCn1cc(-c2cc(C3C(=O)N(CC)c4ccc(C(F)(F)F)cc4N(c4ccccc4)C3=O)cc(OC)c2O)cn1 +CC1CCN(CCCOc2nc(-c3ccccc3)nc3c2CCCC3)CC1 +Cc1nnc2n1-c1sc(C#CCN3C(=O)COc4ccc(Cl)cc43)cc1C(c1ccccc1Cl)=NC2 +CC1=C(C(=O)Nc2cc3cn[nH]c3cc2F)C(c2ccc(C(F)(F)F)cc2)CC(=O)N1 +Cc1cccc(-c2ccc(OC(Cc3ccccc3)C(=O)O)cc2)c1 +O=C(O)CC(O)CC(O)C=Cc1c2c(nn1-c1ccc(F)cc1)C(Cc1ccc(Cl)cc1)CCC2 +Cc1ccc(-n2nc(C)c3c(=O)c4cc(Cl)ccc4n(O)c32)cc1 +Cc1cc(CNc2cc(OCC3CC3c3ccn(C)n3)nn(C)c2=O)nn1C +COc1ccc(S(=O)(=O)N(Cc2cn(C3OC(CO)C(O)C(O)C3F)nn2)C(C(=O)NO)C(C)C)cc1 +CC1CN(C(=O)N2Cc3c(NC(=O)c4ccn(C)n4)n[nH]c3C2(C)C)C(C)CN1CC1CCOCC1 +CCN(CCO)CCN(C(=O)Nc1ccc(F)c(Cl)c1)C1CCC2(c3cccc(C#N)c3)CC2C1 +Cc1cccc(NS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 +COc1ccc(-n2c(C)nnc2N2CCC(Oc3cc(F)cc(F)c3C)CC2)cn1 +CS(=O)(=O)Nc1ccc(OCC(O)CN(CCc2ccc(Cl)c(Cl)c2)CCc2ccccc2O)cc1 +COc1ccc(S(=O)(=O)C(CC(=O)NO)CN(C)C(=O)c2ccccc2)cc1OC1CCCC1 +CC(=O)NC1CCC(NC(=O)c2cnc(-n3ncc4cc(C#N)cnc43)cc2NC(C)C)CC1 +CCOc1ccc(OCC)c(NCC2CCc3nc(N)nc(N)c3C2)c1 +O=C(C1CC(N2CCN(Cc3ccccc3)CC2)CN1)N1CCSC1 +CCc1c(Sc2cc(C)cc(C)c2)n(CC2CCCC2)c(=O)[nH]c1=O +CC(=O)NNC(=S)NC(=O)C(c1ccccc1)c1ccccc1 +Cn1c(=O)c2nc(-c3cccc(O)c3)[nH]c2n(C)c1=O +CC(C(=O)NCCN(c1ccccc1)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCn1ccc(=Nc2ccc(Oc3ccccc3)cc2)c2ccc(Cl)cc21 +COc1ccc(-c2ccncc2)cc1C(C)(C)CC(O)(Cc1cc2ccncc2[nH]1)C(F)(F)F +COc1ccc(Cl)c(Nc2ncnc3cc(OC)cc(OC4CCN(C)CC4)c23)c1 +N#Cc1cccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)c1 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+CCCCn1c2ccc(N)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +Cc1ccnc2c1nc(C1CCC1)n2Cc1cc(=O)[nH]c2c(F)c(F)ccc12 +COC1CCN(c2nc(-c3c(C)cccc3C)nc3c2CN(C(C)c2ccccc2)CC3)CC1(C)C +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1NC(=O)c1ccc(Cl)c(Cl)c1 +Cc1cc(C)nc(N2CC3CN(C(=O)c4cccc(F)c4-c4ncccc4F)CC3C2)n1 +NC1=NC2(CCO1)c1cc(NC(=O)c3ccc(Cl)cn3)ccc1Oc1ncc(C3CC3)cc12 +N#Cc1ccccc1N1CCN(CCCN2CC(=O)N3CCCC3C2=O)CC1 +CC(C)N1Cc2ccc(C(=O)N(C)CCC3CCNCC3)cc2CC(CC(=O)O)C1=O +CCC1CC(C)c2cc3c(C(F)(F)F)cc(O)nc3cc2N1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(C(c3ccccn3)N3CCOCC3)ns2)n1 +C=CCOC(=O)c1c2c3cccc4cccc(c-2nc1=O)c43 +O=c1c(NCc2ccc(Cl)cc2)c(Nc2ccncc2)c1=O +c1cc(-c2c(-c3nc(-c4ccc(Cn5ccnc5)cc4)no3)cnn2C2CCCCC2)ccn1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4ccc(OCCN5CCCC5)cc4)nc23)cc1 +O=S(=O)(Nc1nccs1)c1ccc2c(c1)OCCN2c1cccc(OC(F)F)c1 +N#CC1CC(F)CN1C(=O)CNC1C2CN(c3nc4ccccc4s3)CC21 +COc1ccc2c(c1OC)C13C=C(C#N)CCC1(O)C(C2)N(C)CC3 +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)N3CCCCC3C(=O)O)cc12 +CNC(=O)c1cccc(NC(=O)c2ccc(-c3cc(-c4nnc(C)o4)ccc3C)cc2)c1 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+CS(=O)(=O)Nc1ccc(-c2cnc3cccc(Nc4ccc(C(F)(F)F)cn4)c3c2)cc1 +CCN(CC)CCCOc1ccc(-c2csc(-c3ccccc3)n2)cc1 +CCN(CC)Cc1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12 +O=C(CCc1ccccc1)c1ccccc1OCC(O)CN1CCN(C(c2ccccc2)c2ccccc2)CC1 +CC1CCN(c2ccc3cc(NC(=O)CCc4ccc(C(F)(F)F)cc4)ccc3n2)C1 +CN(C)c1ccc(C(=Cc2ccc(C=CC(=O)NO)cc2)C(=O)NC2CC2)cc1 +CC(=O)NC(C)c1ccc(CN2CCc3c(Cl)cccc3C2)cc1 +Nc1cncc(-c2ccncc2NC(=O)c2nc(-c3ccccc3F)ccc2N)n1 +CC1CC2CC(C)C(C)(C#N)C3CCC4C(C1CCC4(C)C#N)C23 +O=C(CCCC1CCN(C(=O)Cc2ccccc2)CC1)c1ncco1 +O=C(c1nc2c(C(F)(F)F)cc(C3CC3)cn2c1Cl)N1CCN(C2CCC(O)CC2)C(=O)C1 +C=CCN1CC(C)C(N(c2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)CC1C +CC(C)CC(CO)Nc1nc(SCc2ccccc2)nc2nc(N)sc12 +O=C(Nc1cc2c(=O)[nH]c(-c3ccccc3Cl)cc2cn1)C1CC1 +CC(C)(C)NC(=O)NC(C(=O)N1CC2OC(C)(C)C2C1C(=O)NC(CC1CC1)C(=O)C(N)=O)C(C)(C)C +c1ccc2c(c1)CCc1ccccc1N2CCCN1CCN(CCCCNc2c3ccccc3nc3ccccc23)CC1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Oc2ccc(OCC(=O)O)cc2)cc1 +N#Cc1ccc(Nc2nccc(C(=NO)c3ccccc3Cl)n2)cc1 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+CC(C)(C)C(=O)N(Cc1cnc2nc3c(cc2c1)CC1(C3)C(=O)Nc2ncccc21)CC1CCc2ccccc21 +COc1ccc(Nc2nc(Nc3cc(C)[nH]n3)cc(N3CCN(C)CC3)n2)cc1 +Cc1ncnc(-c2ccc(C(=O)N(C)C)cc2)c1C#Cc1ccc(N)nc1 +Cc1cc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(OC(C)C)cc2)ccn1 +Cc1c(O)c(O)c2c(c1S(=O)(=O)N(C)C)CN(Cc1ccc(F)c(Cl)c1)C2=O +Cc1nc(-c2ccccc2F)c2c(N3CCc4noc(C5CC5)c4C3)ncnn12 +Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2ccccc2F)nc1 +NCCC1CNC(=O)c2cc(-c3cccc(OC(F)(F)F)c3)c(-c3ccc4ccccc4c3)n21 +CC(C)Oc1ccc(Nc2ccc(Cc3nc(N(C)C)oc(=O)c3Cl)cc2)cc1F +Cc1ccc(S(=O)(=O)NC(=O)NC(Cc2ccccc2)C(=O)Nc2ccc(S(=O)(=O)N=C(N)N)cc2)cc1 +COc1ccc(C(O)CC2c3cc(OC)c(OC)cc3CCN2C)cc1 +CC(C)(C)OC(=O)NCCCCOc1ccc(S(N)(=O)=O)cc1 +O=C(c1c(NC(=O)C23CC4CC(CC2C4)C3)sc2c1CCOC2)N1CCOCC1 +CC1(C)CCCC(n2c3cnccc3c3cnc(Nc4ccc(N5CCNCC5)cn4)nc32)C1 +O=C(Cc1cc[n+]([O-])cc1)N1CCC(=C2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c32)CC1 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CC(=O)N(C)CCCC)cc1 +CN1CCN(c2ccc(S(=O)(=O)N3CCCCC3)cc2NC(=O)COc2cccc(Cl)c2)CC1 +CC(C)(O)c1cnc2n1CC(c1cccc(F)c1F)CCC2NC(=O)N1CCC2(CC1)OC(=O)Nc1ncccc12 +O=C(Nc1ccc(Cl)cc1)Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +NC(=O)Cc1c(C(=O)N2CCC(O)(c3ccccn3)CC2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +Nc1nccc(-n2cc(-c3cccnc3Cl)c3cnc(Cl)cc32)n1 +O=c1[nH]c(=NOCCc2ccccc2)ccn1C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O +CC(Cn1cnc2c(N)ncnc21)OCP(=O)(NC(C)C(=O)OCC(C)(C)C)Oc1ccccc1 +Cc1cc(S(=O)(=O)NC(C(=O)NO)C(C)C2CC2)ccc1F +COc1cc(C(=O)NC2(C(=O)NC(C)c3ccc(-n4nc(Br)c5ccccc54)cc3F)CC2)on1 +CCCC1NCCOc2ccccc2C=CCNC(=O)C(Cc2ccccc2)NC(=O)C(C)N(C)C1=O +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3cc(F)ncn3)n2)CC1 +NC(Cc1ccccc1)C(=O)NC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CCC(C)C(NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1cccc2ncccc12 +COc1cc(F)ccc1Oc1nc2ccccc2cc1C(=O)Nc1cccc(S(N)(=O)=O)c1 +Oc1cc(O)c2cc(-c3cc(I)c(O)c4ncccc34)oc2c1 +CCOc1cc(C(=CC#N)c2ccc(OC)c(NC(=O)CN)c2)ccc1OC +CCC(C)C(C(=O)NC1CCc2cccc3c2N(C1=O)C(C(=O)NC(C=O)C(=O)O)C3)N(C)C(C)=O +O=C(c1nn(C2CCCN(CC3CCOCC3)C2)c2c1CS(=O)(=O)c1ncccc1-2)N1CCOCC1 +C#Cc1ccc2c(c1)CCN(CCCCN1CCN(c3ccccc3OC)CC1)C2=O +COc1ccc(NC(=O)c2cn(-c3ccccc3)nc2-c2ccc([N+](=O)[O-])cc2)cc1 +O=C(NC(CC1CC1)C(=O)NN1CCC(O)C1)c1ccc(C2CC2)c(OCC2CC2)n1 +O=C(CCC12CC3CC(CC(C3)C1)C2)C(=O)Nc1cccc(OCCCN2CCOCC2)c1 +CCC1CC(C)CC=C1c1onc(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)c1C +Cn1cncc1C(O)(c1ccc(Cl)cc1)c1cc2cc(C(=O)NN3CCOCC3)cc(-c3ccccc3)c2o1 +CC(C)CC(C(=O)NCC#N)c1cccc(-c2ccc(N3CCNCC3)cc2)c1 +CC12CCCC1C1CCC3=CC(=O)C=CC3(C)C1CC2 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(Cc1ccc(Oc3ccc(O)cc3)cc1)CC2 +CNC(=O)c1c(C(N)=O)nc2n1CCOc1cc(F)c(C#CC3(O)CCC3)cc1-2 +CC(=O)NC(CCCCNC(=N)N)C(=O)NCCc1ccc(S(N)(=O)=O)cc1 +Oc1cccc(-c2nc(N3CCOCC3)c3[nH]cc(C4CCN(Cc5ccccc5)CC4)c3n2)c1 +CCNC(=O)Nc1ccc(-c2nc(N3CCOCC3C)c3c(n2)C(C)(C)OC3=O)cc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1C(C)OCC2)c1ccccc1 +CC(CO)Nc1nc(-c2ccc(Cl)c(Cl)c2)c2c(N)c(C(N)=O)sc2n1 +CCc1ncnc(-c2ccc(C(=O)N3CCC(N(C)C)C3)c(F)c2)c1C#Cc1ccc(NC)nc1 +c1ccc(CN2CC(CN3CCC(c4ccccc4)CC3)C(c3cccc(-c4ccsc4)c3)C2)cc1 +O=c1n(-c2ccccc2)nc2c(NS(=O)(=O)c3ccccc3)nc3ccccc3n12 +CCC(C)(C)C(=O)C(=O)N1CCCC1C(=O)OCCCc1cccnc1 +CC1(C)C=Cc2c(ccc3c2OCC(c2ccc(O)cc2O)C3)O1 +CSCCCNC(=O)c1ccc2c(c1)NC(=O)C2=Cc1[nH]c(C)cc1C +CN(C)c1cc(NC(=O)Nc2ccccc2)c2ccccc2n1 +CCOC(=O)C1=C(N)N2C(=O)CCC(=O)N2C1c1ccccc1O +CC(Cl)(Cl)C(NC(=O)c1ccc(Cl)cc1)NC(=NC#N)Nc1cccnc1Cl +COc1ccccc1N1CCN(CCN(C(=O)c2ccc(CCl)cc2)c2ccccn2)CC1 +O=C(c1ccccc1Cl)N1CCC(CNCc2cccc(-n3cccn3)n2)CC1 +N#Cc1ccc(Cn2cncc2CNC2Cc3ccccc3CN(CC3CCCCC3)C2=O)cc1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2cc(Cl)ccc2o1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4cc5ccccc5o4)s3)c2)C(O)C(O)C1O +Cc1ccc(-c2cc(Br)ccc2OCc2cccc(F)c2F)n1-c1cccc(C(=O)O)c1 +CCOC1CN(C2CCN(C(=O)c3ccc4ncccc4c3)CC2)CCC1Cc1ccc(Cl)c(Cl)c1 +CCNC(=S)NNC(=O)Cc1nc2sc(C(=O)OCC)c(C)c2c(=O)[nH]1 +Cc1cccc(NCC(O)CON=C(C2CC2)C2CC2)c1 +COc1ccc(-c2snnc2-c2cc(OC)c(OC)c(OC)c2)cc1[N+](=O)[O-] +Cc1noc(C)c1CCNC(=O)Nc1nc2ccc(-c3cncc(S(=O)(=O)NC(C)(C)C)c3)cn2n1 +COc1ccc2c(c1)OCC1C2=NOC1CN1CCN(CC(C)=Cc2ccccc2)CC1 +COc1cc2c(N)nc(N3CCN(C(=O)CC4CCN4)CC3c3ccccc3)nc2c(F)c1OC +Cc1cc(S(=O)(=O)NC(=N)Nc2ccc(S(N)(=O)=O)cc2)c(SCc2cc(=O)[nH]c3ccccc23)cc1Cl +OC(c1cccnc1)(c1cccc(Cl)c1)c1ccc2nc(Cl)c(Cc3ccc(F)cc3)c(Cl)c2c1 +C=CC1C2Cc3c(-c4nnn[nH]4)n[nH]c3C12 +Cc1ccc(CNCC2(F)CCN(C(=O)c3cc4sccc4s3)CC2)nc1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2c(Cl)cccc21 +CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5cc(Br)ccc5[nH]4)no3)nc2n(CCC)c1=O +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2C(CC(C)C)c2ccccc2)c1 +COc1c(O)cccc1-c1ccc2c(-c3nc4ccccc4[nH]3)n[nH]c2c1 +CCOc1cc2ncc(C#N)c(Nc3ccc(N4CCOCC4)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C +CC(=O)N(C)CCN(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c2ncccc12 +CC(C)c1cc(Nc2cc(Cc3ccccc3)nc(NC3CCC(O)CC3)n2)n[nH]1 +C=CC1CN2CCC1CC2C(O)c1ccnc2ccc(O)cc12 +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3nc(NCCN5CC6CC5CO6)ccc34)cc2)no1 +Nc1nc(N)c2cc(NCc3ccc(C(=O)NC(=O)C(N)CCC(=O)O)cc3)cnc2n1 +COc1ccc2c(c1)oc(=O)n2C1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 +Oc1nc2cc3cc(N4CCCCC4)ccc3[nH]c-2n1 +CCCN(CCC)CCc1c[nH]c2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(Cc1ccc(OC)cc1S)CC(C)C +CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3ccc(OC(F)(F)F)cc3n2)c1)C(=O)O +Cc1cc(C#N)ccc1-c1ccnc(NCc2cc(-c3ccccn3)[nH]n2)c1 +COc1cccc(N2C(=O)c3ccccc3C2(O)c2ccc3c(c2)NC(=O)CO3)c1 +CCC(c1ccc(OC)c(OC)c1)N1C(=O)c2cccc(N3CCN(C(C)c4ccccc4)CC3)c2C1=O +O=C(O)c1cccc(N2CCC(NS(=O)(=O)c3cc(S(=O)(=O)c4ccccc4)ccc3C(F)(F)F)CC2)c1 +CCC(CCOC)n1c(OC)nc2c(-c3ccc(OC(F)(F)F)cc3Cl)ccnc21 +Cc1ccnc(C)c1C(=O)N1CCC(C)(N2CCC(N(c3ccccc3)c3cccnc3)CC2)CC1 +Cc1cc2c(NC(=O)NC3CC(CF)(CF)Oc4c(F)cccc43)cccc2cn1 +O=c1[nH]c(-c2cccc3ccccc23)nc2ccc(N3CCOCC3)cc12 +N#CC1(NC(=O)C2Cc3ccc(c(-c4cccnc4)c3)OCCCCOc3ccccc3C(=O)N2)CC1 +O=C(c1ccc(OCCCc2c[nH]cn2)cc1)C1CCCC1 +Cc1nnc(-c2c(-c3nnc(C(C)(C)C)s3)nn(-c3ccc(Cl)cc3Cl)c2-c2ccc(Br)cc2)s1 +CS(=O)(=O)N1CC2CN(Cc3cn4cc(-c5cnc(N)nc5)nc(N5CCOCC5)c4n3)CC2C1 +c1ccc(C(CN2CCN(CCCCNCc3cccnc3)CC2)c2ccccc2)cc1 +COc1cc2c(Oc3ccc(CC(=O)NN=C(C)c4ccc(C(F)(F)F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 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+CCN(C(=O)Cc1ccc(OC(F)(F)F)cc1)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 +COc1cc2c(=O)n(CCNC(C)C)c3c4cc5c(cc4ncc3c2cc1OC)OCO5 +COc1ccc(C(=O)NCC2(C(F)(F)F)OC(=O)Nc3ccc(Cl)cc32)cc1 +OCc1cccc(-c2nc(N3CCOCC3)c3ncn(C4CCN(c5ccc(F)cc5F)CC4)c3n2)c1 +Cc1ccc(NC(=O)C2CSc3c(C4CC4)c(Cc4cccc5ccccc45)c(N)c(=O)n32)cc1 +O=C(Nc1ccccc1)c1ccc(CC2CCN(C3CCN(C(=O)c4ccc(F)c5ccccc45)CC3)CC2)cc1 +CC(NC(=O)c1ccc2[nH]nc(-c3ccncc3)c2c1)c1ccccc1Cl +COc1cccc(-c2cccc(C3(C)CCSC(N)=N3)c2)c1 +O=c1[nH]c2c(O)ccc(C(O)CNC3CCCCCC3)c2s1 +COc1ccc2c(CC(=O)Nc3cc(Br)ccc3N3CCN(C(=O)OC(C)(C)C)CC3)cc(=O)oc2c1 +CC(NC1=NC(=O)C(C)(C(C)C)S1)c1ccccc1Br +O=c1nc(-c2ccc3[nH]ncc3c2)cc(-c2cccc(Cl)c2)[nH]1 +CN(C(=O)c1ccc(CN2C(=O)Nc3ccc(Cl)cc3S2(=O)=O)cc1)C1CCCCCC1 +COc1ccc(S(=O)(=O)N(Cc2cn(CCOCCOCCOCCN=[N+]=[N-])nn2)C(C(=O)NO)C(C)C)cc1 +O=C1NC2CSC(CCCCCc3cn(Cc4ccc(F)cc4)nn3)C2N1 +CCCCCC12CCC(COc3cc(F)c(C(=O)NS(C)(=O)=O)cc3Cl)(CC1)CC2 +COc1ccc(Nc2ncc3c(n2)-c2ccc(C)cc2NC(=O)C3)cc1OC +CC(C)(C(=O)N1CCC(CC(=O)O)CC1)C(NC(=O)c1ccc(C(=N)N)cc1)c1ccc2ccccc2c1 +Cc1[nH]nc2c1C(c1cc(N3CCS(=O)(=O)CC3)cc(C(F)(F)F)c1)(C(C)C)C(C#N)=C(N)O2 +[H]c1cc([H])c([H])c(-c2nc3c([nH]2)C2=NC(CC)CN2C(=O)N3C)c1 +Cc1cc(Oc2cc(NC(=O)C3CC3)ncn2)ccc1NC(=O)Nc1cc(NC(C)C)cc(C(F)(F)F)c1 +CN1C(=N)NC(C)(c2cc(-c3cccc(C#N)c3)cs2)CC1=O +Cc1cc(NC(=O)Nc2ccccc2)n(-c2ccccc2)n1 +Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3N3CCOCC3)cc2)no1 +CCOCCN1CCN(c2cncc(-c3cn(-c4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4C)nn3)c2)CC1 +C#CCSc1nc(Sc2ccccn2)c2nnn(Cc3ccccc3)c2n1 +CC(C)c1cc(Nc2cc(OCCN3CCOCC3)nc(NCc3cc(-c4ccccc4)no3)n2)n[nH]1 +CC1OC(OC2C(CO)OC(O)C(O)C2O)C(O)C(O)C1NC1C=C(CO)C(O)C(O)C1O +Nc1nc(Cl)c(C#Cc2ccccc2)c(NC2CC(CO)C(O)C2O)n1 +Cc1ccccc1Cc1cc(CCC(=O)O)c2c(c1)CC(NS(=O)(=O)c1ccc(Cl)cc1)CC2 +CCC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1 +Fc1ccc(C(OC2CC3CCC(C2)N3CCOCCN2CCOCC2)c2ccc(F)cc2)cc1 +Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(Cl)cc3)n2)c1 +COc1ccc(-c2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1OCCN(C)C +CC1CCC2C(C)C(CC(=O)NCCCCNCCCN)OC3OC4(C)CCC1C32OO4 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(F)c(F)c3)nn21 +CNC(C)C(=O)Nc1cc(-c2nccc3cccc(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1 +CN(C)C(=O)C1CCC(C(=O)N2CCC3(C)c4ccccc4CC2C3(C)C)CC1 +CCc1cc(C#N)cc2c(NCc3ccc(OC)c(Cl)c3)ccnc12 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)C=CC(C)=O)cc1 +CCC(NC(=O)N1CC(=O)Nc2cccnc21)c1ccc(OC(F)(F)F)c(F)c1 +Cc1ccccc1-c1ccc(C=CC2C3CCC(O)CC3CC3C(=O)OC(C)C32)nc1 +CNCc1cc(C#CCCN2CCCCC2)ccc1Oc1ccc(SC)cc1 +CC(=O)c1ccc(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1 +CCS(=O)(=O)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1 +CN1CCC=C(C2CN(C(=S)Nc3ccc(Cl)cc3)CCO2)C1 +N#Cc1ccc(-c2ccc(C(=O)C(F)(F)F)s2)cc1 +COc1ccc(OC(C)(C)C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)cc1 +O=C(Nc1cccc(Nc2nccc(-c3cccnc3)n2)c1)C1CCCCC1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)N1CCCC1B(O)O +CC(=O)CCCC(=O)NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCCc2ccccc2Cl)C1=O +O=S(=O)(Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1)c1ccccc1 +COc1cc(OC)cc(C(=O)NC(NC(=NC#N)Nc2ccccc2C)C(C)(C)C)c1 +Cc1ccc2[nH]cc3c(=O)n(-c4csc(C)c4)nc-3c2c1 +CC1(C)C=C(c2nc3cc(C(N)=O)ccc3[nH]2)CC(C)(C)N1 +Cc1cn(CC(CO)OCP(=O)(O)O)c(=O)[nH]c1=O +Cn1nc(NCC(=O)NC2CN(C3CCC(C#N)CC3)C2)c2cc(C(F)(F)F)ccc21 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)C2)CCN1Cc1ccc(F)c(Cl)c1 +COc1cc(C#N)cc(-c2cc3nc(C)ccc3cn2)c1 +COC(=O)c1c(NC(=O)c2ccc([N+](=O)[O-])o2)sc2c1CCN(C(C)C)C2 +O=C(NCCCn1ccnc1)c1cnc(N(Cc2ccc(F)cc2)C(=O)CN2CC=CCC2)s1 +COCCOCCOCCOCCOC1CCC2(O)C3Cc4ccc(OC)c5c4C2(CCN3C)C1O5 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1Cc1cccs1 +N=C(N)Nc1ccc(Oc2cccc(Oc3ccc(NC(=N)N)cc3)c2)cc1 +COc1ncc(-c2cnc3[nH]cc(C(=O)c4c(F)ccc(NS(=O)(=O)c5c(F)cccc5F)c4F)c3c2)cn1 +CC#CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CC(=O)c1ccccc1)c(=O)n2C +CCCC1CCCCN1C(=O)C(NC(C)=O)C1CC(C(=O)O)CC1N=C(N)N +COc1cc2nc(-c3ccc(OC)c(N4CCN(C)CC4)c3)cc(O)c2cc1-c1cnco1 +Cc1c(C(Cc2ccc(F)c(F)c2)P(=O)(OC(C)C)OC(C)C)sc2ccccc12 +O=C(Nc1cnc2[nH]ccc2c1)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +NC(=O)Cn1c(=O)c(=O)n(C2CCN(C3Cc4cccc5cccc3c45)CC2)c2ccccc21 +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(C)nn2C)C3=O)c(OC)n1 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+Cn1cncc1CN(CCN(CC1CCCCC1)S(=O)(=O)c1ccccn1)c1ccc(C#N)cc1F +CC(NC(=O)Nc1cc2[nH]nc(-c3cnc(O)nc3)c2cn1)c1ccccc1 +CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O +N#Cc1ccccc1C(O)(c1ccc(Cl)cc1)c1cccnc1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cnn(C)c2)CC1 +CC(C)(C)c1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CC(=O)c1ncc(CNC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)s1 +CC(C)c1n[nH]c2c(=O)[nH]c(CC3CCCCC3Nc3ncccn3)nc12 +CC1(c2ccccc2)CCN(Cc2ccc(Br)cc2)C(=O)O1 +CCn1cc(-c2nc3c(N4CCN(Cc5cc(C)on5)CC4)c(Cl)cnc3[nH]2)cn1 +COc1ccc(C=NNc2cc(N3CCCC3)nc(N3CCCC3)n2)cc1 +CN(C)CCn1cc(S(=O)(=O)c2cccc(Cl)c2)c2cccnc21 +CC(C)COc1ncc(N2C(=O)C3(CC3)c3cc4c(NS(C)(=O)=O)noc4cc32)cc1Cl +O=C(NC(CCC(=O)N1C(C(=O)O)CC2CCCCC21)C(=O)O)OCc1ccccc1 +CC1NC(CO)(CNC(=O)C(N)CO)C(O)C(O)C1O +CC1(C)Oc2ccc(S(=O)(=O)c3ccccc3)cc2C(N=C(NC#N)Nc2ccc(Cl)cc2)C1O +O=C(c1cccc2c1C(=O)N(Cc1ccccc1)C2)N1CCCC1 +CC1=C2C3OC(=O)C4(CC(c5ccc(Br)c(F)c5)=NO4)C3CCC2(C)C=CC1=O +Cc1ccc(CN2CC(C)OC(C)C2)cc1NC(=O)c1ccc(Nc2ncc(C)c(-c3cnn(C)c3)n2)cc1 +CC(=O)Nc1cc(-c2ccc(C)cc2)cc(-c2ccc(C)cc2)n1 +CCN(CC)C(=O)c1ccc(NC(=O)NC(Cc2ccc(O)cc2)C(=O)NC2CCN(Cc3ccc(C#N)cc3)C2)cc1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccn(Cc2cccc(Cl)c2)c(=O)c1 +CCN(Cc1cccc2ccccc12)c1cc(N2CCOCC2)nc(=O)[nH]1 +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cn[nH]c3)nc12 +O=C(CC1CNCCN1c1cc(Cl)nc(-n2ccnc2)n1)NCc1ccc2c(c1)OCO2 +CC(O)C(O)C(=O)N(CCCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1ccccc1 +COc1cc(Nc2ncnc(-c3cccnc3Nc3cccc(C(=O)Nc4ccc(Oc5ccccc5)cc4)c3)n2)cc(OC)c1OC +COc1cncc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +COc1ccc(Cn2ccc3nc(N)nc(NCc4cc(C)on4)c32)nc1OC +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(Cl)cc3)nc(CO)c12 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCC(NCc2ccc(Cl)cc2)CC1 +N#CC1CN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)C1 +CC(C)c1n[nH]c2c(=O)[nH]c(CC3CCCCC3OCCN3CCOCC3)nc12 +Nc1nnc(-c2ccc3[nH]cc(-c4csc(-n5ccccc5=O)n4)c3c2)s1 +COc1ccc(N(Cc2ccc3ccccc3n2)C(=O)c2ccc(C=CC(=O)NO)cc2)cc1 +c1ccc(CCn2nnnc2C(c2cccnc2)N2CCN(c3nc4ccccc4s3)CC2)cc1 +Nc1nccc(-c2c[nH]c3cc(C(F)(F)F)ccc23)n1 +COc1cc2cc(CO)c(CO)c(-c3cccc(-n4nc(-c5cccnc5)c5ccccc5c4=O)n3)c2cc1OC +C1=CCc2c(-c3ccccc3)[nH]c(-c3ccccc3)c2C1 +CC1CCN(C(=O)c2ccc3c(c2)c2c(n3S(=O)(=O)N(C)C)CCN(C3CCCC3)C2)CC1 +O=C(Cc1c(-c2ccccc2)nc2c(Cl)cc(Cl)cn12)N1CCc2ccccc2C1 +CCCc1nc2[nH]c(-c3ccccc3)nc(-c3ccccc3)c-2n1 +c1ccc2c3c([nH]c2c1)C(C1CCOCC1)NC(c1nc(C24CC5CC(CC(C5)C2)C4)c[nH]1)C3 +CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OCCCCc1ccccc1 +Cc1cc(C2C3CCC(CC2c2ccc(F)cc2)S3)on1 +CCc1cc(Oc2c(C)cc(NC(=O)C(=O)O)cc2C)ccc1O +O=C(O)C1=CCCN(CCOC(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)C1 +CC(C)COc1ccc(CN(Cc2ccc(F)cc2)C(=O)NC2CCN(C)CC2)cc1 +c1cc(C[n+]2ccc(C3CCCCC3)cc2)cc(-c2cccc(C[n+]3ccc(C4CCCCC4)cc3)c2)c1 +COc1cnc(NCc2ccccc2)nc1-c1cc2c([nH]1)CCNC2=O +NC(=O)c1cc(S(N)(=O)=O)c2c(c1)nc(NCc1ccccc1Cl)n2CC1CCCCCC1O +CCN(CC)CCOc1cccc(-c2cc(C(=O)NC3CCCNC3)c(NC(N)=O)s2)c1 +Cc1ccccc1C(CC(=O)O)NC(=O)c1cc(Sc2ncccn2)ccn1 +CCNc1c(C(N)=O)nnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc12 +O=C(c1ccc(C(=O)N2CCCc3ccccc32)cc1)c1cnc2ccccn12 +COc1nc(-c2cn3c(n2)C(c2cc(Br)ccc2C(F)(F)F)CCC3)ccc1-n1cnc(C)c1 +CCc1cn(-c2ccc(C(N)=O)c(NCCN3CCOCC3)c2)c2nccc(-c3cnc4ccccc4c3)c12 +Cc1c(C(=O)NCCO)sc2ncnc(Nc3ccc(F)cc3OC(CO)CO)c12 +Cc1cc(C)c(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1NC(=O)c1ccc(N2CCOCC2)nc1 +CCNc1cc(Cl)cc2c1[nH]c1cnc(NCc3ccccc3)cc12 +Nc1ncnc2nc(-c3cccs3)c(Cc3cccc(Br)c3)cc12 +Oc1nc2cc(-n3ccnc3)c(C(F)(F)F)cc2nc1O +CNc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2F)ncn1 +CCN(Cc1ccc(OC)cc1)Cc1ccc(-c2cc(S(=O)(=O)CC)ccc2OC)[nH]1 +O=C(c1nnco1)C1CCc2cc(Oc3ccccc3)ccc2C1 +COc1cc(CN(CC2CCCC2)C(C(=O)O)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CCC1=O +CC(=O)c1cccc(CC(NC(=O)c2c(Cl)cc3c(c2Cl)CCN(C(=O)c2ccc4ccoc4c2)C3)C(=O)O)c1 +CC(NC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1)c1cnn(C)c1 +CN1CCC(NC(=O)c2csc(NC(=O)c3ccc4cc5n(c4c3)C3(CCC3)CNC5=O)n2)CC1 +NC1=NC(c2cccc(NC(=O)c3ncc(Br)cc3O)c2)(C(F)F)COC1 +CC1CN(C(C)(C)CO)CCN1C(=O)CC1(C2COCC(C3CC3)N2S(=O)(=O)c2ccc(F)cc2)CC1 +N#Cc1cccc(N=Nc2c(Cl)nc(N)nc2NC2CC(CO)C(O)C2O)c1 +C=CCN1CCC23c4c5ccc(O)c4OCOC46CCC2(OC(C(=O)N4Cc2ccccc2)C63)C1C5 +COc1ccc(S(=O)(=O)N(Cc2cccnc2)C(CCF)C(=O)NO)cc1 +CC(C)S(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CCC(N4CCC(F)(F)CC4)CC3)cc2C(N)=O)cc1 +Cc1cccc(CCOC(=O)C2=C(c3ccccc3)CCN(C)C2)c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(OCc4ccc(Cl)cc4)nc23)N1 +CC(C)CC(C(=O)NCC#N)c1cccc(-c2cccc(-c3csc(N4CCN(C)CC4)n3)c2)c1 +CC(=O)NC(C(=O)N1CCCCC1)C1CC(C(=O)O)CC1N=C(N)N +Cc1c(N)cc(-n2c(C)ccc2-c2cc(C(F)(F)F)ccc2OCc2ccccc2)cc1C(=O)O +CC(=O)OC(C)C(=O)Nc1cccc(-c2n[nH]c3ccc(-c4nn[nH]n4)cc23)c1 +C[N+](C)(C)CCOc1cnc2c3c(cccc13)C(=O)c1ccccc1-2 +NC(=O)C[S+]([O-])C(c1ccccc1)c1cccc(Br)c1 +CCCCCCCCNC(=O)C1CCC2C3CCC4N(C)C(=O)C=CC4(C)C3CCC12C +CC(C)(C)n1nnnc1C(c1cccc(Nc2ccnc3cc(Cl)ccc23)c1)N1CCCC1 +COc1cc(O)c2c(c1C(=O)NCc1cc(OC(C)=O)cc3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)C12C +O=C(Nc1ccc(Cl)cc1)NC1N=C(c2ccccc2)c2ccccc2N(CC(O)CO)C1=O +O=C(CN1CCN(Cc2ccccc2)CC1)c1c[nH]c2ccc(O)cc12 +OCCn1cc(-c2cc(OCCC34CC5CC(CC(O)(C5)C3)C4)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +Cc1ccc(N(CC2=NCCN2)c2cccc(O)c2)cc1 +N#Cc1cc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cnc1N1CCC(O)C1 +Cc1nnc2n1-c1sc(C#CCn3ncc4ccccc43)cc1C(c1ccccc1Cl)=NC2 +CC(C)n1cnc2c(NCc3ccc(-c4ccoc4)s3)nc(NC3CCC(N)CC3)nc21 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCCN(C(=O)C(C)C)C2)cc1 +NC(CC(=O)N1CCn2nnc(-c3ccoc3)c2C1)Cc1cc(F)c(F)cc1F +CCCCCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 +O=C(C=Cc1ccc(O)c(O)c1)c1ccc(S(=O)(=O)N2CCCCCC2)cc1 +Nc1ccn(C2OC(COP(=O)(O)OC(C(=O)N3CCCCC3)P(=O)(O)O)C(O)C2O)c(=O)n1 +O=C(Cc1ccccc1)Nc1nc2nn(CCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +NC(C(=O)N1CCN(c2ccc3[nH]ncc3c2)CC1)c1cccc(Cl)c1 +Nc1nccn2c(C3CCC3)nc(-c3cccc(OCc4c(F)cccc4F)c3)c12 +O=C(O)CC(c1ccc(OCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1)c1cccnc1 +Cc1ccccc1N1CCN(Cc2ccc(C(O)c3ccccc3)cc2)CC1 +O=C(Nc1cc(-c2cccc(NS(=O)(=O)c3ccccc3)c2)n[nH]1)c1ccc(N2CCOCC2)cc1 +CC(C)(C)OC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 +COc1ccc(-c2cc3c(NC(=O)CC4CCCC4)ncnc3o2)cc1 +CN(CCO)c1nc(NC2CCCC2C#N)c2cc[nH]c(=O)c2n1 +N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(F)c2)n2cnnc2)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)C2CC3C=CC2C3)CC1 +CC(C)(C)COc1cc(C(C)(C)C)ccc1CN=C(S)NCc1ccc(NS(C)(=O)=O)cc1 +Cn1cc(C(=O)N2CCC(c3cccc(CN)c3)CC2)c2ccccc21 +CC(C)Oc1nc(NC2CCOC2)ncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 +COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(F)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 +CCc1nc(N)nc(N)c1-c1ccc(NCc2ccnc(Cl)c2)cc1 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCCC2)CC1 +Cn1ccc2cc(C(=O)N3CCc4c(cnn4-c4ccccc4Cl)C3)ccc21 +Cc1cc(C)cc(C(CC(C)C)NC(=O)c2cc(COc3cccc(Cl)c3)ccc2CCC(=O)O)c1 +C=C1C(=O)C23C(=O)OC4CCC(C)(C)C5C(O)OCC45C2CCC1C3OC(=O)c1ccc(OC)cc1 +Oc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1 +CC(C)=CCn1cc(C[N+](C)(C)C)c2ccccc21 +CC(C)c1cn2ccccc2c1S(=O)(=O)c1ccc(OCCCNCCc2ccccc2)cc1 +COCCN1C(=O)Cc2ccc(-c3ccc(CC(C#N)NC(=O)C45CCC(CC4)CN5)c(F)c3)cc21 +COc1cc2c(cc1N1CC(C)N(C)C(C)C1)N(C(=O)Nc1cccc(C(F)(F)F)c1F)CC2 +Cn1c2c(c3cc(C(=O)N4CCCCC4)ccc31)CN(C1CCOCC1)CC2 +Cc1cc(Oc2ccnc(NC(=O)C3CC3)c2)ccc1NC(=O)Nc1cc(C(C)(F)F)ccc1F +O=S(=O)(Nc1cccc(CCc2ccccn2)c1)c1cc(Cl)ccc1Cl +CC(O)CNc1nccc(-c2nc(C3CC3)[nH]c2-c2cccc(NS(C)(=O)=O)c2F)n1 +CC1(COc2cc(F)c(C(=O)NS(=O)(=O)N3CCC3)cc2C2CC2)CCC(C(F)(F)F)CC1 +COc1ccc(-c2nc(-c3ccncc3)cnc2N)cc1OC +COCC(=O)NCCNc1nc(-c2ccc(C(C)(C)O)nc2)cc2ncn(C)c(=O)c12 +Cc1ccc(C(=O)N2CCOCC2Cc2cc(Cl)cc(-n3nccn3)c2)c(-n2nccn2)c1 +CCOC(=O)c1nc(-c2ccc(F)cc2)c(-c2ccc(S(C)(=O)=O)cc2)s1 +CCCCc1ncc(CO)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(CNC(=O)CCCCCN2CCN(c3ncccc3-c3ccncc3)CC2)cc1 +Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(O)ccc2n1 +CNC1CCN(C2CCC(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 +O=S(=O)(NCCCN1CCOCC1)c1ccc2c(c1)Cc1c-2nc(O)c2ccccc12 +COc1ccc(C(C)C)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 +CCCN(CCN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)c(F)c1)S(=O)(=O)CC(C)C +CCC(Cc1ccccc1)c1cc(O)c(C(c2cccc(NS(=O)(=O)c3cccc4cccnc34)c2)C2CC2)c(=O)o1 +CCc1nc(-c2ccccc2)c(C)c(-c2ccc(F)cc2)c1CCP(=O)(O)CC(O)CC(=O)O +CNc1ncnc2c1ncn2C1OC(CN(CCCNC(=O)Nc2ccc(C(C)(C)C)cc2)C(C)C)C(O)C1O 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+N#Cc1cc(-c2ccnc(Nc3ccc4c(c3)CC(=O)N4)n2)ccc1N1CCCC1 +O=C(C1CCCN(c2ccc3nc(-c4cncc(C(F)(F)F)n4)[nH]c3n2)C1)N1CCCC1 +Cc1ccc(C(Nc2nsnc2Nc2cccc(C(=O)N(C)C)c2O)C(C)(C)C)o1 +CC(C(=O)Nc1ccc(C(=O)O)cc1)n1ccc(-c2cc(Cl)ccc2C#N)cc1=O +COc1ccc(C2CC2COc2cc(NCc3cc(C)on3)c(=O)n(C)n2)nc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc4[nH]ccc4c3)NC(=O)NC1=O)C2 +COC1(c2cc(Sc3ccc4c(c3)OCC(=O)N4C)cc(F)c2C)CCOCC1 +CCOc1ccc(S(=O)(=O)N2CCOCC2)cc1-c1nnc2c(n1)c(C)nn2C +C#CCn1c(=O)c2c(nc3n2CCCN3C2CCC2)n(C)c1=O +CCCCCCCCNC(=O)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)Cc1ccccc1 +CC1CC(=O)NN=C1c1ccc(N)c([N+](=O)[O-])c1 +C#CCN(C)CC(=C)c1cccc(OCc2ccc(OC)cc2)c1 +OCC1OC(c2cc(Cc3ncc(-c4ccco4)s3)c(Cl)cc2F)C(O)C(O)C1O +CC(C)c1cccc(NC(=O)C2CC(N)CN2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 +Fc1ccccc1CC1=NC(c2ccccc2)C(c2ccccc2)N1 +NS(=O)(=O)NCCCCC(NC(=O)OCc1ccc(Cl)cc1)C(=O)Nc1nc(-c2ccccc2)cs1 +NCC(O)CNc1cc(N2CCC(c3ccccc3)CC2)nc2ccccc12 +COc1cc(NC(=N)NC(=O)c2ccccc2)ccc1-c1cnco1 +CN1CCN(c2ccc3[nH]nc(S(=O)(=O)c4cccc(F)c4)c3c2)CC1 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+[O-][S+](Cc1cc(Oc2ccc(F)cc2F)ccn1)c1nc2cscc2[nH]1 +O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(-c3nc4cc5[nH]cnc5cc4nc3-c3ccccc3)cc2)CC1 +Cc1cc(C)c(Nc2nc(N)nc(NC3CCN(Cc4ccc([N+](=O)[O-])cc4)CC3)n2)c(C)c1 +CCc1nc2cccnc2n1-c1ccc(Nc2nc3ccccc3s2)cc1 +CC1OC(=O)C2CC3CCCCC3C(CCCN3CCSCC3)C12 +C=CC(=O)N1CCc2c(sc3ncnc(NC(C)c4ccccc4)c23)C1 +CCOC1CCC(CS)(C(=O)NC(Cc2cccs2)C(=O)Nc2ccccc2)CC1 +CCC(C)C1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)N1CCOCC1)c1ccc(C)nc1 +O=CC(CC1CCCNC1=O)NC(=O)C(Cc1ccc(F)cc1)NC(=O)C=Cc1ccc(F)cc1 +Cc1cc(-c2cncc(OCC(N)Cc3c[nH]c4ccccc34)c2)cc2ccncc12 +COc1cc(-c2nc(-c3ccnc(C)c3)c3n2CC(CF)OCC3)ccc1OC(F)(F)F +N#CCCC(Oc1cc(OCc2ccccc2)ccc1C(=O)O)c1ccccc1 +CC(=Cc1noc(Cn2cnc3ncn(C)c3c2=O)n1)c1ccc(Cl)cc1 +CNCc1cccc(-n2cc3cccc(C(N)=O)c3n2)c1 +COc1cc(-c2cc(NC(=O)Nc3ccc(OCCCN(C)C)cc3)cc(OC)c2OC)ccc1C(C)=O +O=C(O)CN1C(=O)C(NC(=O)C(CS)Cc2ccccc2)CSc2ccccc21 +O=C(O)C1CCCN1C(=O)c1cccc(COc2ccc(-c3cc(F)cc4c3OCC=C4)cc2)c1 +O=C(c1ccc([N+](=O)[O-])cc1)N1Cc2ccccc2C(c2ccccc2)c2ccccc21 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+CCCCC1(CCCC)C(O)C(c2cccc(NC(=O)CCCCBr)c2)c2cc(N(C)C)ccc2S(=O)(=O)N1C +Cc1ccccc1CC(O)C=CC1C(O)CC(=O)C1SCCCSCC(=O)O +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2cc(Cl)ccc12 +CC(Oc1cc(-c2ccc3[nH]cnc3c2)cc2ncccc12)C1CNC(=O)C1 +CCc1c(Sc2ccc(Br)cc2)[nH]c2nc(N)nc(N)c12 +CC(C)OC(=O)Nc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1)Nc1ccc(C(F)(F)F)cc1Cl +Cc1ccc(C#N)c(OCc2ccc(C(=O)Nc3ccccc3N)cc2)n1 +Cc1nc(NC(C)c2cccc(OCCn3ccnc3C)c2)cc(-c2ccc3ncsc3c2)n1 +COc1ccc(C(=O)CC(=O)CC2CCN(Cc3ccccc3)CC2)cc1OC +COC1(c2ccc(Cl)cc2)CCN(Cc2c[nH]c3ccccc23)CC1 +O=C(Nc1ccc(Cl)nc1)c1ccc(C(F)(F)F)c(F)c1 +Nc1ccccc1NC(=O)c1ccc(NC(=S)NCc2nc3ccccc3[nH]2)cc1 +CC1(C)CC(Nc2ccccc2S(=O)(=O)Nc2ccc3c(c2C(=O)O)CCCC3)CC(C)(C)N1 +Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4nc(C)c(C)n4-5)CC3)cccc2n1 +Cn1c(C#Cc2cc3ccc(Br)cc3[nH]2)cc2ccc(Br)cc21 +[C-]#[N+]c1cccc(-c2ccc3c(c2)CN2CCC3(c3ccc(Cl)cc3)CC2)c1 +C=CCN1C(=O)n2c(cc3c(OC)cc(OC)cc32)C1=S +NC(=S)Nc1cccc(OCCCCCOc2ccc(-c3ccccc3)cc2)c1 +O=C(CCc1c[nH]c2ccccc12)NCCCN1CCC2(CCc3ccccc32)CC1 +Cc1cc2cc(OCC(=O)O)cc(Cl)c2n1Cc1ccc(O)c(C(C)C)c1 +COc1ccccc1N1CCN(CCC2CCc3ccc(N)cc3C2=O)CC1 +COc1ccc(Cl)c(NC(=O)Nc2cc(Nc3ccc(N4CCN(C)CC4)cc3)ncn2)c1Cl +CNC(=O)c1c(NCC2CCC3(CCC3)CC2)nc(C#N)nc1OC1CC(C)(C)NC(C)(C)C1 +COc1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)cc1CCCN(C)C +CCN(CC)Cc1ccc(-c2cccc(CN(C)C(=O)CN)c2)cc1 +CC(C)c1nc2cc(Cl)c(Cl)cc2nc1S(C)(=O)=O +CNC(=O)C1Cc2cc(-c3ccncc3)ccc2N1C(=O)COc1ccc(F)cc1 +O=C(Nc1ccc(F)cc1)Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +Cn1c(=O)ccc2c(NC(=O)NC3CC(CF)(CF)Oc4cc(Cl)ccc43)cccc21 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)CNCc2cccc(OC)c2)c1 +COc1cc2c(cc1-c1ccc(I)cc1)NC(=O)CC(c1cccc(-n3ccnc3)c1)=N2 +NC(=O)c1c(NC(=O)c2ccc(OCc3ccccc3)cc2)sc2c1CCN(Cc1ccccc1)C2 +Cc1cc(C(=O)NC(C)(C)C)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 +O=C(COCc1ccncc1)N1CCC(c2ccc(F)cc2Cl)CC1 +[O-][n+]1nc2c(I)cnn2c2cc(OCCCl)ccc21 +CN(C)CCCCCNc1c2ccccc2nc2cccc([N+](=O)[O-])c12 +CCOc1cc(F)cc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)c1 +C=CCN(C(=O)OCc1ccccc1)C1CCN(CCC(Cn2c(CC)nc3ccccc32)c2ccccc2)CC1 +Cc1c(CNC2CCCC2)nn(-c2ncccc2Cl)c1-c1ccc(Cl)nc1 +O=C(Nc1ccc2c(c1)OCO2)c1ccccc1Cn1ccc2cnccc21 +O=C(CCc1ccc(Cc2ccccc2)cc1)c1ncc(-c2ccccn2)o1 +CN(c1ccc(-c2cc(C(F)(F)F)ccc2OCC(=O)O)c(Cl)c1)S(C)(=O)=O +Cc1c(Nc2c(C#N)cncc2C=Cc2ccc(CN3CCOCC3)cc2)ccc2[nH]ccc12 +Cc1ccc2nc(NC(=O)Nc3ccccc3N3CC4(CCN(CC(C)(C)C)CC4)c4c(C#N)ccc(O)c43)sc2c1 +COc1ncc(-c2ccc3ncc(NC(=O)CN4CCN(C)CC4)c(OC)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +CN(C)CC(=O)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CNC(=O)OC(C)(C)C)c3)s2)nn1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4ccc(Cl)cc4)nc31)C(O)C2O +COc1cc2ncccc2cc1NC(=O)c1csc2cnc(NC3CC3)nc12 +COc1ccc2c(c1)c(CC(=O)Nc1ccc(SC)cc1)c(C)n2C(=O)c1ccc(Cl)cc1 +COc1ccc2c(c1)c(C)c(CCC(=O)O)n2C(=O)c1ccc(Cl)cc1 +CCN1CCC2(CCN(c3cncc(-c4cn(-c5cc(C(=O)Nc6cc(C(C)(C)C)on6)ccc5C)nn4)c3)C2)C1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccoc3)n(CC(=O)N3CCC(O)CC3)c2c1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(N4CCNCC4)cc3)NC(=O)NC1=O)C2 +CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(-c2ccco2)c1 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+O=S(=O)(c1cccc(C(F)(F)F)c1)N1C2Cc3n[nH]cc3C1c1cc(F)c(F)cc12 +CN(Cc1ccccc1)C(=O)c1cc2ccccc2c(-c2ccccc2Cl)n1 +Cc1cc(-c2cccc(Cl)c2C=CC2CC(O)CC(=O)O2)ccc1F +c1ccc2c(CCNc3ccc(Nc4ccncc4)cc3)c[nH]c2c1 +CCN(CC)CCCS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(N4CCOCC4)ccc3Cl)sc2c1 +N#Cc1ccc(C(=O)NC2CCCC(n3c(-c4ccccn4)nc4cc(C(N)=O)ccc43)C2)s1 +COCc1nc2c(n1Cc1ccccc1)C(=O)N(C)C1=NC3CCCC3N12 +CC1CCCN1c1cccc(Nc2cc(-c3cccc(CN4CCCC4)c3)nn3ccnc23)n1 +N#CC1(c2ccc(NC(=O)c3cccnc3NCc3ccncc3)cc2)CCCC1 +COc1cc(C(=O)C(=O)N2CCN(C(=O)c3ccccc3)CC2C)ccc1-c1cc(C)no1 +C=CC(=O)Nc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OCCNC(=O)CS(C)(=O)=O +CCc1ccccc1OCCNCCCCN1C(=O)C2CCCN2C1=O +O=C(O)CNC(=O)c1cccc2c1ncn2-c1ccccc1 +COc1cc(CCC(=O)Nc2ccc(C(=O)NO)cc2)ccc1OCc1cccs1 +Cn1c(-c2ccc(CN3CCCC3)cc2)nc2onc(-c3ccccc3Cl)c2c1=O +Cc1ccc2c(OCCN3CCC(Cc4ccc5c(c4F)NC(=O)CO5)CC3)cccc2n1 +CC(C)(C)OC(=O)N(Cc1ccccc1)Cc1ccc(C=CC(=O)NOC2CCCCO2)cc1 +CC(=O)NCc1cccc(-c2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +COCCN(c1cc(OC)cc(OC)c1)c1ccc2ncc(-c3cnn(C)c3)nc2c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3n[nH]c4ccccc34)cc(N3CCN(C)CC3)n2)c1 +CCc1cccc2cc3cccc(C(=O)NCCN(C)C)c3nc12 +Cc1c(CC(=O)O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(Cl)c1 +CCn1nc(Cc2ccccc2)cc1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2cccc(F)c2)CC1 +CN1C(=O)NCC1C(=O)NCc1ccc(F)c(C(F)(F)F)c1 +O=[N+]([O-])c1cccc(-c2cc(-c3cc(Br)ccc3O)n[nH]2)c1 +Cc1noc(C)c1-c1ccc2c(c1)C(CCCN1CCN(C)CC1)(c1ccccc1)C(=O)N2 +COc1cccc(CNCCCNc2ccnc3cc(-c4ccccc4)ccc23)c1O +Nc1ccccc1NC(=O)c1ccc(CNC2=NC(=O)C(Cc3c[nH]c4ccccc34)N2)cc1 +COc1cc(C(=O)c2c[nH]c3c(Cl)c(OC)ccc23)cc(OC)c1OC +COc1ccc(N(C)c2ccc3nc(N)nc(N)c3n2)cc1 +CCC1(O)c2cc3n(c(=O)c2COC(=O)C1OC(C)=O)Cc1c-3nc2ccccc2c1C1CCN(C)CC1 +CN1CCN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)CC1 +O=C1CCC(=O)N1CCCOc1ccc(C2Oc3cc(O)ccc3C3=C2c2ccc(O)cc2OCC3)cc1 +O=C(COc1ccccc1-c1ncc[nH]1)NCC(O)CN1CCc2ccccc2C1 +CC(=O)N1CC2C=C(c3cnc(NCc4ccc5c(c4)OCC5)c(C(=O)NCC4COc5ccccc5O4)c3)CC1CC2 +CCCCNc1nc(NCCCCCCC(=O)NO)c2ncn(Cc3ccccc3)c2n1 +CCOC(=O)c1c[nH]c2ncnc(-c3cccc(Cl)c3)c12 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCn1c([N+](=O)[O-])cnc1C +NC(=O)CCn1ccc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc21 +Cc1cc(C)c(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(C(=O)C2CC2)c1 +CCc1cc2c(cc1-c1cnn(C3CCOC3)c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CCCC(CC)Nc1nc(C)nc2c1ncn2-c1ccc(C(C)C)cc1Br +Cc1oc(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)Nc2ccccc2)nc1C(=O)O +CC(C)(C)CN(Cc1ccc(C=CCN2CCC(N3CCCCC3)CC2)cc1)c1ccnc(C#N)n1 +COc1ccc(Cn2c(=O)n3ncnc3c3c4c(sc32)CN(CC2CCOCC2)CC4)cc1 +Cc1ccn2cc(C3CC3c3cc(-n4nc(C)nc4C)nc(C)n3)nc2c1 +C=C(C)c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)c(OC)c1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cc4ccccc4o3)cc2)no1 +COc1cccc(CC(=O)Nc2ccc3cc(C(=O)NO)sc3c2)c1 +CC(C)CS(=O)(=O)N1CCC(NC(c2cnccn2)c2ccc(F)cc2F)CC1 +CNc1cc(-c2ccccc2)cc(C(Cc2ccccc2)NC(=O)C2CCC(CN)CC2)n1 +O=C(NC1CCC(O)CC1)c1cnn2ccc(NC3CCc4ccccc43)nc12 +CCCCNC(=O)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1C(=O)NCc1cccnc1 +CCc1ccccc1-n1c(Cn2nc(-c3cc(O)cc(F)c3)c3c(N)ncnc32)cc2cccc(C)c2c1=O +Cc1nc(C2CC2c2nc3ccc(Cl)cc3[nH]2)cc(-n2nc(C)nc2C)n1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCc1ccccc1 +CC(C)(C)c1cc(NC(=O)c2ccc(F)c(Nc3ncnc4cnc(NC5CCOC5)nc34)c2)no1 +Fc1cccc(F)c1-c1ccc2[nH]nc(-c3cncc(OC4CNCCC45CC5)n3)c2c1 +O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCNCC1 +NS(=O)(=O)C1OC(COP(=O)(O)O)C(O)C(O)C1O +O=c1oc(-c2cccc([N+](=O)[O-])c2)ns1 +CCCS(=O)(=O)N1CC2C(C1)C2(CNC(=O)c1ccc(Cl)cc1Cl)CC1CC1 +CC(C)N1CC(C(=O)N2CCN(c3ccccc3CN3CCC(N)CC3)CC2)C(c2ccc(Cl)cc2)C1 +CCOc1ccc(C(=Cc2cc(OC)c(OC)c(OC)c2)C(=O)N2CCC=CC2=O)cc1 +CC1(C)Oc2cc(C#Cc3ccccc3C(F)(F)F)ccc2-c2nc(-c3c(Cl)cncc3Cl)[nH]c21 +O=C(CCCCc1cccs1)Nc1ccc2c(c1)CC(C(=O)O)OC2 +COC1CCC2(CC1)Cc1ccc(C(C)C)cc1C21N=C(N)N(C(C)C)C1=O +CCc1nc(N)nc(N)c1-c1ccc(Cl)c(N=NN(CCOC(C)=O)Cc2ccc3ccccc3c2)c1 +O=c1[nH]c2ccccc2c(=O)n1CCN1CCN(C2CC(c3ccc(F)cc3)c3ccccc32)CC1 +NS(=O)(=O)NCCCCC(NC(=O)OCc1ccccc1)c1nc2ccccc2[nH]1 +Cc1[nH]c2ncccc2c1C1CCN(C(=O)C(C)(C)c2ccc(Cl)cc2)C1 +CCC(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1N +CNc1cc2c(c3ccccc13)C(CCl)CN2C(=O)c1cc2cc(OC)c(OC)c(OC)c2[nH]1 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+O=C(Cn1cc([N+](=O)[O-])nc1[N+](=O)[O-])N1CCN(c2ccc(F)cc2)CC1 +COC(=O)c1ccccc1OCC(O)CNCCNC(=O)Cc1ccccc1 +COc1cc(F)c(-c2cccc(C(=O)Nc3cnccc3C3CC(N)CC(C(F)(F)F)C3)n2)c(F)c1 +NC(=O)C1Cc2cc(C=CC(=O)N3CCC(COc4ccc(F)cc4)CC3)cnc2NC1=O +CCCCN1C(=O)C(=CNCC(C)C)C(=O)c2cccc(C)c21 +CC(C)(O)C(=O)N1CC(C#Cc2ccc3c(=O)c(-c4ccc(NS(C)(=O)=O)cc4)coc3c2)C1 +NC(=NCC1CCCCC1)c1c(O)nsc1Nc1cc(Cl)cc(Cl)c1 +C=CC(=O)Nc1ccccc1Nc1nc(Nc2ccnn2C)ncc1Cl +Cc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2ccccc2F)cc1 +Cc1c(C(=O)NCCCCCCCNS(C)(=O)=O)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +COc1ccc2nnc(C(=O)N3CCC(c4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)n2c1 +COc1cc(-c2ccc3c(N)n[nH]c3c2)nc(N)n1 +N#CC1CCC(C#N)N1C(=O)CNC12CC3CC(CC1C3)C2 +CC1Cn2c(nnc2-c2cnccn2)C(=O)N1Cc1cccc(C(F)(F)F)c1 +COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(OC(F)(F)F)cc1 +O=c1c2ccoc2ccn1C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O +CN1CCCC1CCNC(=O)CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1 +CN1CCc2c(-c3n[nH]c4ccnc(OC5CCOCC5)c34)cccc21 +COc1ccc(CNc2nc(N3CC4CC4C3)ncc2C(=O)NC2CCC(O)CC2)cc1F 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+Cc1ccccc1-n1c(Cn2nc(-c3cc(O)cc(F)c3)c3c(N)ncnc32)cc2cccc(F)c2c1=O +COC1C(O)C(C)OC(OC2CCC3(O)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)C1O +Cc1ccc(F)cc1-c1cc2cnc(NC(=O)C3CC3)cc2c(C)[n+]1[O-] +O=C(O)c1c(CCCOc2cccc3ccccc23)c2cccc3c2n1CCC3 +CCOP(=O)(CCc1ccccc1)N1Cc2ccccc2CC1C(=O)NO +COCC(S)C(=O)NC1(C(=O)NC(Cc2ccc(-c3ccccc3)cc2)C(=O)O)CCCC1 +O=C(NCCN1CCC(n2c(O)nc3ccccc32)CC1)c1ccc(F)c(F)c1 +N#CCOc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2 +COc1cccc2c1nc(N)n1nc(CN3CCN(c4cccnc4)CC3C)nc21 +Cn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(C(=O)NOCCO)cc21 +CC(Oc1cc(-n2cnc3ccc(CC(O)CO)cc32)sc1C(N)=O)c1ccccc1Cl +O=CN(O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)C(CO)CO +CC#CCn1c(NC(C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc(-c3cnco3)cc1)CC2 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CC(CCC)CCC +Cc1ccc(-n2ccc3c(sc4nccc(NC5CC5)c43)c2=O)cc1 +C[S+]([O-])c1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCC3=CC(=O)CCC3(Cc3ccc(NS(C)(=O)=O)cc3)C2)cc1 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+O=C(NC1CCCCC1)Oc1cccc(C2=NC(Cc3ccccc3)CO2)c1 +COc1cnc2c(NCc3nnc4ccc(-c5cnn[nH]5)nn34)ccnc2c1 +COc1ccc(-c2csc(Nc3ccc4ccccc4c3)n2)cc1OC +Cc1cc(C)c(-c2nc3c([nH]2)C(C)N(C)CC3)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +CC(C)(C)c1cc(NC(=O)c2ccc(F)c(Nc3ncnc4cnc(NC5CCOC5)nc34)c2)[nH]n1 +COC(=O)N1CCc2nc(C)n(C3CC4CCC(C3)N4CCC(NC(C)=O)c3ccccc3)c2C1 +CN1CCC(c2cc(NC(=O)Nc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cc3)cc(C(F)(F)F)c2)CC1 +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncnc2ccc(O)cc12 +COc1ccc(C(=O)CC(CC(=O)c2ccc(Cl)cc2)c2cccc(C(=O)O)c2)c(OC)c1OC +CCCCOc1ccc(OC(C(=O)N(C)O)c2ccccc2)cc1 +NC(=O)c1cc(F)ccc1Cn1ccc2cc(C(=O)NO)ncc21 +CCN(CC)Cc1cc(S(=O)(=O)c2coc(S(N)(=O)=O)c2)ccc1O +CCOc1ccc(-c2ccc(NCc3ccccc3O)cc2)cc1 +Cc1cc(C(=O)N2CCC2)ccc1C1CCCN1C(=O)c1cc(Cl)c(O)cc1O +O=C(O)c1ccnc(-n2ncc(CCO)c2OCc2ccc(F)cc2)c1 +COC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)cc3)C2)C1c1ccccc1F +N#Cc1ccc(C(=O)CN2C(C(=O)c3ccccc3)=C(O)c3ccccc3S2(=O)=O)cc1 +CC1Cc2c([nH]c3ccccc23)Cc2ccccc2CCN1C +COC(=O)C1(c2ccc(-c3ccc(CCN4CCCC4C)cc3)cc2)CCCC1 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+O=S(=O)(C=Cc1cccc(Cl)c1)Nc1cccc(OCc2cn(Cc3cc4ccccc4s3)nn2)c1 +OC1(Cc2cc(-c3cn[nH]c3)on2)CCC(Cc2ccc(F)c(F)c2)CC1 +Cc1ccc(C(=O)NC2CCCCC2NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)cc1 +CC1CCC2C(C)C(CCNCc3ccccn3)OC3OC4(C)CCC1C32OO4 +Cc1nc(C(=O)NCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c(C)n1-c1ccccc1 +COc1ccc(-c2cc3c(C)nc(N)nc3n(CC3CCOC3)c2=O)cn1 +Cc1cc(C)c2cc(C(=O)c3cnn(-c4ccc5[nH]c(C)nc5c4)c3N)[nH]c2c1 +OCc1cccc(Nc2nc(-c3ccncc3)nc3ccccc23)c1 +NS(=O)(=O)c1ccc(NC(S)=NC(CS)C(=O)O)cc1 +NS(=O)(=O)c1ccc(CCN=Cc2ccc(O)cc2)cc1 +Cc1cc(F)ccc1C(=COCCN1CCC=C(C(=O)O)C1)c1ccc(F)cc1C +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1c2ccccc2CC1C1CC1 +COc1ccc(CNC(=O)CCc2nc3cccnc3n2Cc2ccccc2)cc1 +O=C(NC1CCC2CN(Cc3ccc(F)cc3)CC21)C(C1CCCCC1)C1CCCCC1 +COC(=O)CC(c1cccnc1)C(C(=O)N(C(C)C)C(C)C)c1ccccc1 +NC(=O)CCNC(=O)C1C(C(=O)NCc2ccc(Br)cc2F)C2CCC1C21CC1 +COc1ccc(OC)c(CC(=O)NCCCNCCCCCCCCNCCCNC(=O)Cc2cc(OC)ccc2OC)c1 +CCOC(=O)N1CCN(C(=O)c2ccc(-c3ncnc(CC)c3C#Cc3ccc(N)nc3)cc2OC)CC1 +Cc1c(S(=O)(=O)NCCCN2CCC(c3noc4cc(F)ccc34)CC2)sc2ccc(F)cc12 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+CCCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2ccc3ncccc3c2C1 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-n3nnc4ccccc43)ccnc12 +CC1CC[N+]2(C)CCc3c([nH]c4ccccc34)C2C1 +Cc1ccccc1C(=NOCCN1CCCC(C(=O)O)C1)c1cccc(Cl)c1 +OCc1ccc(-c2cn(C3CN4CCC3CC4)nn2)cc1 +CSc1c(Cl)nc(-c2ccc(NC(=O)Nc3ccc(N4CCN(C)CC4)nc3)cc2)nc1N1CCOCC1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCCC(CCO)C3)cc2F)cn1 +O=C(Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1)N1CCN(c2ccc(F)cc2)CC1 +Cc1nc2ccc(Br)cc2c(-c2ccc(Cl)cc2)c1C(C)C(=O)O +C#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1Cl +O=C(NC(Cc1ccccc1)P(=O)(O)CC1(C(=O)NC(Cc2ccc(O)cc2)C(=O)O)CCCC1)OCc1ccccc1 +NC(=O)Nc1cc(CC(c2ccccc2)C2CC2)ccn1 +Cc1cccc(C)c1C(=O)N1CCC(N2CCN(Cc3ccc(Cc4ccc5c(c4)OCO5)cc3)C(C)C2)CC1 +Oc1ccc(-c2cc(C=C3CN4CCC3CC4)on2)cc1 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)c1cc(F)c(F)c(F)c1)CC2 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(C(=O)OCC(F)(F)CO)CC1 +C=CC(=O)Nc1cc2c(Nc3ccc(OCc4cccc(F)c4)cc3)ncnc2cc1OC1CCOC1 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+O=C(c1ncc(-c2ccccn2)o1)C1Cc2ccc(Oc3ccccc3)cc2C1 +CCCCn1c(CNc2ccc(C(=N)N)cc2F)nc2cc(C(=O)N(CCC(=O)O)c3ccc(F)c(Cl)c3)ccc21 +CN1CCN(C2(c3nc(-c4cnc(N)c(-n5nnc6ccccc65)n4)nn3C)CC2)CC1 +COc1cccc(C(Nc2ccccn2)c2oc(CO)cc(=O)c2O)c1 +COc1cc(N2CC(=O)N(c3ccc(Oc4ccccc4)cc3)C2=O)ccc1OCCN1CCCC1 +CC(NC(=O)C(O)C(O)C(=O)N1CCCC1c1csc(N2CCCCC2)n1)c1ccc(-n2cccn2)cc1 +COc1ccc(-c2cc(-c3ccco3)nc(N)c2C#N)cc1 +O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(O)c1 +COc1cccc(-n2ncc3c(NN=Cc4ccc(N)cc4)ncnc32)c1 +Cc1nc2c(NCc3ccncc3)cc(Cl)nn2c1-c1cccc(S(=O)(=O)N(C)C)c1 +COc1cccc2c1ncc1c(=O)n(-c3ccc4c(c3)OCO4)c(=O)n(C3CCCC3)c12 +Cc1nn(C)cc1CC(=O)Nc1cncc(C(=O)c2cn(C(C)(C)C)c3ncncc23)c1 +Cc1cc(C#N)cnc1C(=O)Nc1cnc(F)c(C2(CF)CC(C(F)(F)F)OC(N)=N2)c1 +CC(Nc1ncnc2[nH]c(-c3ccc(NCCCCCC(=O)NO)cc3)cc12)c1ccccc1 +COc1cc2ncc(C(N)=O)c(Nc3cccc(C)c3)c2cc1OC +Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(N2CCC3(CCNC3)CC2)nc1 +Cc1nc(O)c2cc(CN(C)c3cc(F)c(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c3)ccc2n1 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+CC1CN(CCC(O)c2csc3ccc(F)cc23)CCN1c1cccc2c1OCO2 +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCCC1C(N)=O +COc1ccc(-c2cnnn2-c2cc(OC)c(OC)c(OC)c2)cc1[N+](=O)[O-] +CC(C)CC1C(=O)NC(C(=O)NC(C)C(=O)N2CCOCC2)CCCCNC(=O)OCCCC1C(=O)NO +CN(C)CCCCNC(=O)c1cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(Cl)c2[nH]1 +O=C(NCC(NC(=O)c1c(Cl)cc(CCC(O)c2cccc(O)c2)cc1Cl)C(=O)O)c1cccs1 +CC(C)(C)COc1ncnc2[nH]cc(C=CC(N)=O)c12 +Cc1noc(C)c1-c1ccc2c(c1)C(c1ccccc1)(N1CCC(N)C1)C(=O)N2 +COc1ccc2c(c1)C(=O)C(c1ccc(C)cc1)=[N+]2[O-] +CC(CC(O)N1CCCC(Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(-c2nccn2C)c1 +Cc1cnc(NC(=O)C2(C)CC3c4ccccc4C2c2ccccc23)s1 +O=C(Nc1ccc(OC2CCN(CC3CCCC3)CC2)cc1)N1Cc2ccncc2C1 +Oc1nc2ccc(C#CCN3CCC(O)(Cc4ccc(F)cc4)CC3)cc2s1 +CCCCN(CCCC)CCCOc1ccc(S(=O)(=O)c2c(CC)cn3ccccc23)cc1 +CCc1nn(Cc2ccc(OCc3cccc(C)c3)cc2)c(CC)c1CC(=O)O +Cc1ccc(C2(O)CCC(N3CCC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cn1 +CCc1nccc(-c2ccc(C(=O)N3CCN(C4CCCC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +Cc1ccc(S(=O)(=O)N2CCN(C)C(=O)C2CC(=O)NC2CCCc3cc(CN4CCCCC4)ccc32)cc1 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+Cn1cc(-c2ccc3cn[nH]c3c2)c(-c2ccncc2)n1 +Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)CCCC(=O)O)O2)c(=O)[nH]c1=O +CCN(CC(=O)N(C)C)Cc1ccc(CCNC(=O)c2ccc(-c3ccc(Cl)cc3)cc2)cc1 +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc(N(C)C)cc2)cc1 +CCOC(=O)c1c(-c2cccc(Oc3ccccc3)c2)[nH]c2cc(O)ccc2c1=O +CC(C)N(C)C(=O)c1nc(-c2ccccc2Cl)c2ccccc2n1 +Cc1c(Cc2ccc(F)c(C(=O)N3CCN(C(=O)C4(NCC5CC5)CCCC4)CC3)c2)n[nH]c(=O)c1C +O=CC(Cc1ccccc1)NC(=O)c1ccccc1C=Cc1ccccc1 +CN1N=C2CCN(C(=O)C(COCc3ccc(F)c(F)c3)NC(=O)C(C)(C)N)CC2(Cc2ccccc2)C1=O +COC=C(C(=O)OC)c1ccccc1COc1nc(Nc2ccc(Cl)cc2Cl)nc(C(F)(F)F)c1C +COc1cc(OCc2nsc(-c3ccccc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C1C=C2N(C(=O)c3cc4cc(Cl)ccc4[nH]3)CC3CC23c2ccccc21 +COc1cc2c(cc1OC)C(c1ccnc(-n3nc(-c4cccnc4)c4ccccc4c3=O)c1)=NC(CO)C2 +CCCCCCCCCC(=O)OCc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F +Cc1cc(C)nc(N2CC3CN(C(=O)c4c(C)cccc4C)CC3C2)n1 +Fc1ccc(CN(CCC(F)(F)F)Cc2sc(Nc3c(Cl)cc(Cl)cc3Cl)nc2C(F)(F)F)cc1 +COc1cccc(Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1Cl +Cc1ccccc1C1CCN(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)OC3CCCC3O)CC2)CC1 +Oc1ccc(C=NNC(=S)NN=Cc2ccc(O)cc2)cc1 +Cc1c(NC(=O)c2ccc(-c3ccc(F)cc3)cc2)ccc2cc(CN3CCCC3)cnc12 +N#Cc1cnc(C(=O)Nc2ccc(C3CCNCC3)cc2C2=CCS(=O)(=O)CC2)[nH]1 +CC(C)Oc1nc(N)c(C(N)=O)c(OC2CCCCC2)n1 +Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OCC(F)F)c(C3CC3)cn2)no1 +COc1c(CC(=O)O)cccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +CC(=O)C1C(C(COC(N)=O)COC(N)=O)CC2C3CCC4CC(O)CCC4(C)C3CCC21C +CN1CCN(Cc2cc(NC(=O)c3ccc4c(c3)CN(c3cncnc3)CC4(C)C)cc(C(F)(F)F)c2)CC1 +O=C(O)C1CCCN(CCC=C(c2ccccc2)c2ccccc2)C1 +CCc1cn(C2CC(O)C(CNC(=O)Cc3ccccc3C(F)(F)F)O2)c(=O)[nH]c1=O +Cc1csc2nc(C(C)NC(=O)C=C(Sc3ccccc3)c3ccccc3)oc(=O)c12 +CCN1CCN(Cc2ccc(C#CC3(CN4Cc5ccc(OC)cc5C4=O)NC(=O)NC3=O)cn2)CC1 +COc1ncc(F)cc1C1CCCN1c1ccn2ncc(C(=O)NC3CCN(S(C)(=O)=O)CC3)c2n1 +CCCCc1ccc(NC(=O)C(=O)NCCN2CCN(Cc3ccc([N+](=O)[O-])cc3)CC2)cc1 +Cn1ccc(C2=NCC(=O)N3CCc4c(cccc4N4CCOCC4)C3=C2)n1 +O=C(O)c1cccc(C(CC(=O)c2ccccc2)CC(=O)c2ccc(F)cc2)c1 +CN1CCN(c2ccc(C(=O)Nc3n[nH]c4cc(OCC=Cc5ccccc5)ccc34)cc2)CC1 +CC(=O)Nc1ccc(NC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)cc1 +O=C(O)c1cc(=O)c2cc(F)cc(NC(=O)c3ccc(Cl)cc3Cl)c2o1 +O=C(O)CCCc1cn(Cc2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)c2ccccc12 +CCCOc1ccc2c(c1)c(-c1ccc3c(c1)OCO3)c(C(=O)O)n2-c1ccc2c(c1)OCO2 +COc1ccc(-c2nc3cc(-c4cccc(Cl)c4)ccc3o2)cc1N1C(=O)c2ccc(C(=O)O)cc2C1=O +CCc1c(N)ncnc1N1CCN(C(CN)c2ccc(Cl)cc2)CC1 +Cc1c(C)n(-c2ccccc2)c2nc(-c3ccccc3Cl)nc(N)c12 +O=C(Nc1ccc(=O)[nH]c1)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O +CCCCOP(=O)(CC(CCc1ccccc1)OC(C)=O)OCCCC +CC1(C)Cc2cc(-c3cc(C(N)=O)ccc3Cl)ccc2N(C(=O)c2c(F)cccc2Cl)C1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(C(C)CC)C(C(=O)O)c2ccccc2)cc1 +Cc1cc(-n2ccnc2)cc2[nH]c(-c3c(NCC(C)c4cccc(Br)c4)cc[nH]c3=O)nc12 +Cc1nc(-c2ccccc2)[nH]c1-c1cnc(-c2ccccc2)nc1 +Nc1nc2c(ncn2C2CN(C(=O)CP(=O)(O)O)CC2OC(=O)CP(=O)(O)O)c(=O)[nH]1 +O=S(=O)(c1cccc(F)c1)c1ccc2c(c1)CCNCC2 +O=C(Nc1nc2c(N3CCOCC3)ccnn2c1-c1ccc(N2CCNCC2)nc1)c1ccc2ccccc2n1 +CS(=O)(=O)N(CCN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1)c1cccc2ccccc12 +CN(C)c1ccc2nc3ccc(N4CCCC4)cc3[o+]c2c1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 +N#Cc1ccc(Cn2cncc2CNC2CCN(C(=O)c3cncc(Br)c3)C2)cc1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)nc31)CN1CCC2CC1 +N=C(N)C1CCCC(NC(=O)CN2CCCC(NS(=O)(=O)c3cccc4ccccc34)C2=O)C1O +Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(=O)O +CCOC(=O)c1c(-c2ccc(-c3ccc(OC(F)(F)F)cc3)cn2)[nH]c2ccccc2c1=O +CC(F)c1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(=O)c1ccc(OC(C)C)c(-n2c(CN3CCN(C(=O)COc4ccc(Cl)cc4)CC3)nc3ccccc3c2=O)c1 +Cc1cc(C(C)C)nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)n1 +CCCN1CCC(CNC(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)(C(=O)NO)CC1 +Cc1cccc(-c2csc(N3CCC4(C(=O)O)CC4C3)n2)c1OCc1ccc2c(c1C)CCN(C1CCOCC1)CC2 +C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1CCC)C(C)(C)CCC2(C)C +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(Cc2cccc3cc[nH]c23)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2ccc(N)nc2)c1F +O=C(c1ccc(Br)cc1)N1CCN(C(=O)c2ccc(-c3nccs3)cc2)CC1 +COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C(=O)N2 +O=C(CN1CCCC(c2nc3ccccc3n2Cc2ccc(F)cc2)C1)N1CCCCC1 +COC(=O)c1ccc(Nc2nc(N3CCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1F +CCC(NC(=O)c1c(Cl)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +C1=C(c2ccc(CCN3CCCC3)cc2)C2CN(c3cncnc3)CC2C1 +O=C(CCC(F)(F)F)N1CCC(CCCCNC(=O)N2Cc3ccncc3C2)CC1 +N#Cc1cc(-c2ccnc(Nc3ccc(N4CCOCC4)cn3)c2)ccc1OCC1CC1 +CC1CN(c2ccc(Nc3ncc4c5ccnc(F)c5n(C5CCCC5)c4n3)nc2)CC(C)N1 +CCN(c1ncccn1)C1CCN(CC2CN(C(CC3CCC3)C(=O)O)CC2c2cccc(F)c2)CC1 +CC#CCn1c(N2CCCC(N)C2)c(C#N)c2ncn(CC(=O)c3cccc(OC)c3)c(=O)c21 +CC(=O)c1cnc2ccc(-c3ccc4nc[nH]c4c3)cc2c1NC1CCC(CN(C)C)CC1 +CCc1ccc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CN1CCN(Cc2ccc(-c3cc4ncc(C#N)c(Nc5ccc(Oc6ccccc6)cc5)c4s3)cc2)CC1 +O=C1c2cc3c(cc2C(=O)N1CCC1CCN(Cc2cccc(F)c2)CC1)OCO3 +C=C(C)CC1(O)CCC2(C)C(CCC3(C)C2CCC2C4C(C(=C)C)CCC4(C(=O)O)CCC23C)C1(C)C +NCc1cccc(C2CCN(C(=O)c3c[nH]c4ccccc34)CC2)c1 +CC(C)N1CCN(C2CCCn3nc(COc4ccccc4)cc32)CC1 +COc1ccc(CC(=O)N2CCN(c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)CC2)cc1 +Clc1ccc(Nc2nc(Nc3ccccc3)c3ccccc3n2)cc1Cl +COC(=O)CCc1ccc2c(c1)C(n1ccc3ccccc31)=CC(=O)C2=O +N#Cc1cc(-c2ccnc(Nc3ccc(CN4CCNC(=O)C4)nc3)n2)cnc1N1CCC(F)C1 +CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NC(CO)CC(C)C +CCCCCC(O)C=CC1C=CC(=O)C1CCCCCCC(=O)O +CN(C)C(=O)c1ccc(Nc2cc3c(-c4cnn(C)c4)cccc3cn2)c(Cl)c1 +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccc(C)cc2)c2ccc(Cl)c(Cl)c2)CC1 +CCCCn1cc2c(nc(NC(=O)Nc3ccccc3Cl)n3nc(-c4ccco4)nc23)n1 +COc1cc(-c2cc(=O)c3cc(Cl)cc(Cl)c3o2)ccc1O +COc1ccc2c(c1)OC(C)(C)c1cn(CNC(=O)CN3CCN(c4ccccc4OC)CC3)nc1-2 +CCC(C)C(CNC(C(=O)NC(CCO)C(=O)O)C(C)CC)NC(=O)C(N)CS +NS(=O)(=O)c1ccc(Nc2nc(=O)[nH]c(=O)[nH]2)cc1 +O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccc(Cl)cc1 +CC1(C(=O)N(CC#N)Cc2ccc(Cl)cc2)CCN1C(=O)Cc1csc2ccccc12 +Clc1ccc(Nc2nccc(-c3ccc4c(c3)OCO4)n2)cc1 +CNCC(Nc1ncnc2c1=CCCC=2C(N)=O)c1cccc(NC(=O)c2ccc(C(F)(F)F)cc2)c1 +COc1ccc2c(c1)CN(c1ccc(N(C)C)cc1)C2=O +CN1CC(C(=O)NCc2ccccc2-c2ccccc2)=C(O)C1=O +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C2CCCCC2)cc1 +CC1CN(CCC(=O)N(Cc2ccc(-c3ccccc3)cc2)C(Cc2ccccc2)C(=O)O)CCC1(C)c1cccc(O)c1 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+C=C(C)C(=O)c1ccc(OCc2nc(-c3ccc(C(F)(F)F)cc3)no2)cc1Cl +O=C(CCCCCNc1nc(Cl)nc2c1ncn2Cc1ccccc1)NO +COc1ccc(Cc2cccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)c2)cc1 +CCN1CCC(Nc2cnc3ccc(C#CCNC(=O)c4cccn(C(C)c5ccc(F)c(F)c5)c4=O)cc3c2)CC1 +COc1cc2ncc(C#N)c(Nc3cccc(O)c3)c2cc1OC +O=C(NC1CCCC1NC(=O)c1ccc(-n2ccccc2=O)cc1)c1ccc(Cl)cc1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(C#N)c(OC)ccc3nc2-1 +Fc1ccc(CN2CCN(CCSC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +COc1cc(C=CCc2cc(OP(=O)(O)O)c3ccoc3c2)cc(OC)c1OC +CN1CCN(C(=O)CNc2nc(Nc3ccc(F)cc3)nc3ccccc23)CC1 +CN1CCN(Cc2cc(Nc3nc4cc(Oc5ccnc6[nH]ccc56)ccc4o3)ccc2Cl)CC1 +CC1Oc2c3c(c4c(-c5ccccc5)cc(=O)oc4c2C(O)C1C)OC(C)(C)C=C3 +COc1ccc2c(CC(=O)Nc3ccccc3S(N)(=O)=O)cc(=O)oc2c1 +CC(C(=O)NCCCCCCCCNc1c2c(nc3ccccc13)CCCC2)c1ccc(-c2ccccc2)c(F)c1 +O=C(c1nn(-c2ccccc2)c2c1CS(=O)(=O)c1ncccc1-2)N1CCOCC1 +CCCN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(c3ccc(F)cc3)=NN12 +O=C(Nc1ccc(Oc2ccccc2)cc1)c1cccnc1Nc1ccc2cn[nH]c2c1 +CNC(C(=O)NC(C(=O)N(C)C(C=C(C)C=O)C(C)C)C(C)(C)C)C(C)(C)c1ccccc1 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+O=C(NCCc1nc(-c2ccncc2)n[nH]1)C12CC3CC(CC(C3)C1)C2 +CCC(C)N(CC(=O)Nc1cc(F)cc(F)c1)C(=O)c1ccc(-c2ccccn2)cc1 +O=c1[nH]c(=O)n(C2CC(O)C(COP(=O)(O)O)O2)cc1Cl +CCCN1CCC(Cc2ccc(F)cc2)CC1CCCNC(=O)Nc1cccc(C(C)=O)c1 +COc1ccc2ccn(CCn3cc(NC(=O)c4ncoc4-c4cccc(C)c4)cn3)c2c1 +CCCn1cc(C(=O)c2cccc3ccc(C)cc23)c2ccccc21 +Cn1c2cc(OCCCN3CCCC3)c(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +CCOc1cc2ncnc(Nc3ccc4c(cnn4Cc4ccccc4)c3)c2cc1NC(=O)C=CCN1CCN(C)CC1 +COc1ccc(NCc2cncn2C)c(C(=O)NC2CCN(Cc3ccc4c(c3)OCO4)CC2)c1 +COc1cc2c(N)nc(N3CCN(C(=O)CC4CCCCN4)CC3c3ccccc3)nc2c(F)c1OC +Cc1ccc(N2CCc3ncnc(NC(CO)c4cccnc4)c3C2)nc1 +CCC(CNCc1cccc2[nH]ccc12)C(=O)N(Cc1cc(Cl)c2c(c1)OCCCO2)CC(C)C +CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(Cl)c2)CC1 +COc1cc(-c2cc(NC(=O)Nc3ccc(OCCCN4CCOCC4)cc3)cc(OC)c2OC)ccc1C(C)=NO +Cc1cccc(C)c1N(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)c1ncccn1 +COc1cc2oc(C(=O)NC3CCN(Cc4ccc5c(c4)OCO5)CC3)cc(=O)c2cc1F +N=C(N)c1ccc(-c2ccc(N3CCN(CC(=O)O)CC3)cc2)cc1 +N=C(N)Nc1ccc(CNC(=O)N2CCN(C(=O)NC3CCC(c4ccccc4)(c4ccccc4)CC3)CC2)cc1 +OCC(O)CN1CCC(c2cc3c(-c4cncc(NCc5ccccc5)n4)ccnc3[nH]2)CC1 +Fc1ccc(NC(=S)c2ccco2)cc1-c1nc2ncccc2o1 +O=S(=O)(Nc1ncns1)c1cc(F)c(Oc2ccc(C(F)(F)F)cc2C2=CCNCC2)cc1F +CCN1CCN(C(=O)c2ccc(NCc3ccc(-c4cccc(F)c4C(=O)OC)cc3F)nc2)CC1 +Cc1cc(OC(F)F)cnc1C(=O)Nc1ccc(F)c(C2(C(F)F)COCC(N)=N2)c1 +O=C(NC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1)c1ccc2cn[nH]c2c1 +COc1ccc(CCNCC(O)COc2ccc(Cc3nc(C(C)=O)c[nH]3)cc2)cc1OC +N#CCC1(n2cc(C(N)=O)c(Nc3cncc(F)c3)n2)CCN(C(=O)OCC(F)F)CC1 +Cn1c(=O)c2c(nc3n2CCN3C2CCCCCCC2)n(C)c1=O +Cc1ccc(CNCC2(F)CCN(C(=O)c3cc4ccccn4n3)CC2)nc1 +COc1ccc2c(c1)CCN1C(=O)C3CCCC(C21)N3S(=O)(=O)Nc1ccc(F)c(F)c1 +O=C(c1ccc2cc(OCCCN3CCCCC3)ccc2c1)N1CCC(CO)CC1 +O=C(NC1CCC(CCN2CCc3sccc3C2)CC1)c1cc2ccccc2[nH]1 +Cc1ccc(S(=O)(=O)c2c(C(=O)NNCCO)[nH]c3ccc(Cl)cc23)cc1 +CC(C)(C)OC(=O)N1CCC(C(NS(=O)(=O)c2ccc(-c3ccccn3)s2)C(=O)O)CC1 +O=C(NO)c1ccc(-c2ccn(CCNCc3ccc4occc4c3)n2)s1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCC(NCc2ccccc2Cl)CC1 +CCc1nc2cc(O)ccc2c(Oc2ccc(C=CC(=O)O)cc2)c1-c1ccccc1 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+O=C(Nc1ccc2c(c1)OCO2)C1C(c2ccc(Cl)c(Cl)c2)OC2(C(=O)c3ccccc3C2=O)C1C(=O)O +CCCCOc1ccc(-c2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)cc1Cl +O=c1cc(OCc2ccc(F)cn2)ccn1-c1ccc2c3c([nH]c2c1)CCNCC3 +CC(C)c1cc(CNc2nc(Nc3cc(C(C)C)[nH]n3)cc(N3CCOCC3)n2)on1 +O=C1N(c2ccc(OCc3ccccn3)nc2)CCN1c1ccc(Cl)c(Cl)c1 +Nc1nc(NCCNc2ncc(NC(=O)CCCN3CCOCC3)c(-c3ccc(Cl)cc3Cl)n2)ccc1[N+](=O)[O-] +Cc1cccc(N2CCCCCC2)c1CNC(N)=NC(=O)c1ccc(CC(N)C(=O)O)cc1 +O=C(c1ccc(Nc2nc3ccccc3n3nnnc23)cc1)N1CCN(C2CCOCC2)CC1 +CSc1nc(-c2ccc(OC(F)(F)F)cc2)nn1C(=O)N(C)c1ccccc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC(N)C(O)CC1 +CCN(CC)c1c(NC(Cc2ccc(-c3ccccc3OC)cc2)C(=O)O)c(=O)c1=O +NCC1CN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)C1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)cn3)c2)c2cnc(N)nc21 +O=C(c1ccc2[nH]ccc2c1)C1(Cc2ccccc2)CCCCNC1 +COc1cc(C(=O)NCCN(C)C)cc(OC)c1-c1cc2c(NC(C)c3ccccc3)ncnc2s1 +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NCc1cccc(F)c1F)CC2 +COc1ccc(CNC(=O)CN(C(=O)c2cc3ccccc3[nH]2)C(C(=O)NC(C)(C)C)c2ccc(OC)cc2)cc1 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+Cc1cc(C)cc(Sc2c(Cn3cncn3)c(C)[nH]c(=O)c2I)c1 +COc1ccc(C(=O)N2c3ccccc3S(=O)(=O)c3ccc(Cl)cc32)cc1 +Cn1cc(-c2ccc(-c3cncc4ccc(C(=O)NC5CC5)cc34)cc2)cn1 +O=S(=O)(Nc1ccccc1F)c1ccc2c(c1)CCNCC2 +CN1Cc2c(-c3ccncc3)[nH]c3nccc(c23)-c2cc(F)ccc21 +CCOC(Cc1ccc(OC(=O)Cc2nc(-c3ccccc3)oc2C)c(C)c1)C(=O)O +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(Cl)c(Cl)c3)ncc12 +COc1cc(C2c3cc4c(cc3C(OC(=O)c3cc5ccccc5s3)C3COC(=O)C23)OCO4)cc(OC)c1OC +CCNc1ncc(C(=O)Nc2cc(C(=O)Nc3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)ccc2C)cn1 +CCOC(=O)c1ccc(N2CCN(c3nnc(Cc4ccc(F)cc4)c(C)c3C)CC2)nc1 +CCc1nn(-c2ccccc2)c2nc(-c3ccc(N4CC(C)NC(C)C4)cc3)cc(OC)c12 +COC(=O)c1ccc(C(=O)N2CCC(CNCc3cccc(-n4cccn4)n3)CC2)cc1Cl +O=C(NO)C(CNS(=O)(=O)c1ccc(OCc2ccccc2)cc1)N1CCCCC1 +O=C(Nc1ccc(S(=O)(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O)cc1)c1ccc(Br)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2ccc(C3CC3)cn2)cc1 +Cc1ccc2c(OCCN3CCC(Cc4cccc(NS(C)(=O)=O)c4)CC3)cccc2n1 +COc1ccc(OC)c(-c2c(F)ccc3c(N)c4c(nc23)CN(C2CC2)C4=O)c1 +CS(=O)(=O)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1 +N#CC1CC(F)CN1C(=O)C(N)Cc1ccc(OCc2ccccc2)cc1 +NS(=O)(=O)c1ccc(N2CCN=C2c2ccc(Cl)c(Cl)c2)cc1 +COc1cc(-c2[nH]c(-c3ccoc3)nc2-c2ccc(N(C)C)cc2)cc(OC)c1OC +Cc1c(Sc2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(=O)O +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N4CCC(C)(C)C4)n3)C2)cc1 +O=C(c1ccc(F)nc1)N1CCCC1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +N#CC1CN(c2cnc(C(=O)Nc3csc(-c4nncn4C4CC4)n3)cc2-n2cnc(C3CC3)c2)C1 +COc1cc(Nc2c(C#N)cnc3cc(-c4cc(CN5CCC(O)CC5)cs4)ccc23)c(Cl)cc1Cl +O=C1OCC2=C1C(c1ccc(F)c(Br)c1)C1=C(CCCS1(=O)=O)N2 +CCCNC(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +CCCCCCCCCCCCn1nnc(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccc(F)cc2)n1 +Clc1cccc(N2CCN(CCCCN3CC4CCCN4C3)CC2)c1 +COc1cc(C=Cc2ccc(N(C)C)c(N)c2)cc(OC)c1OC +CCCOc1cc(CN2CCN(C)CC2)cc(-c2ccc(S(=O)(=O)Nc3c(C)nn(C)c3C)cc2)c1 +CC1=C(C)C(=O)C(CCC(C)(O)CCCC(C)CCCC(C)CCCC(C)C)=C(C)C1=O +COc1ccc2cc1COCC=CCOCc1cccc(c1)-c1ccnc(n1)N2 +COc1ccc(-c2c[nH]c3ncc(-c4ccc(OCCN5CCOCC5)c(N)c4)cc23)cc1OC +COc1cc(N2CCC(N(C)C)C2)c2[nH]c(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1 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+CC(C)CNS(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1 +CCN(Cc1cc(C(F)(F)F)ccc1-c1nn(CC(=O)O)c2cccc(C#N)c12)C(=O)C1CC1 +Cc1cc(C(=O)NC(Cc2cccc(Cl)c2)C(=O)NCC#N)c(C)s1 +Clc1ccc(C23CCNCC2(Cn2ncc4ccccc42)C3)cc1Cl +N=C(N)NC1Cc2ccccc2C1NC(=O)C(=O)Nc1ccc(Cl)c(F)c1 +O=C(NCc1ncco1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CS(=O)(=O)N1CCCC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +Cn1nc(-c2ccc(F)cc2)c(-c2ccc3nc(NC(=O)c4ccncc4)cn3n2)c1C1CCN(CCO)CC1 +O=C1c2ccccc2COc2ccc(CC(=O)N(O)C3CCCCC3)cc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2ccc(O)cc2)CC1 +COc1nn(-c2ccc(NC(=O)c3ccc(C(C)(C)C)cc3)cc2)c(=O)o1 +COc1cc2c(cc1O)CCC1C2CCC2(C)C(c3cncc4c3CCCC4)CCC12 +Fc1cccc(Nc2nc(SC3CCCC3)nc3c2cnn3CC(Cl)c2ccccc2)c1 +CC(C)(c1cc(-c2cccc(C(=O)Nc3ccccc3)c2)c2ncccc2c1)S(C)(=O)=O +O=C(O)c1ccc2c(c1)nc(Nc1ccccc1)c1nc(NC3CC3)ncc12 +Cc1c(-c2ccc3c(c2)OCO3)n(Cc2ccc(OCCN3CCCCC3)cc2)c2ccc(O)cc12 +COC(=O)C1=C(Nc2ccc(Cl)cc2)CC(c2ccc(F)cc2)N(c2ccc(Cl)cc2)C1c1ccc(F)cc1 +COc1ccc(NC(=NC#N)NC(NC(=O)Cc2ccc(OC)c(OC)c2)C(C)(C)C)c(OC)n1 +C=CC(C)(C)c1c(O)cc2oc3cc(O)c(O)c(CC=C(C)C)c3c(=O)c2c1O +CC(C)c1onc(COc2ccccc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +COc1c2c(c(O)c3ncc(Cc4ccc(F)cc4)cc13)C(=O)N(C)C2 +CCCCCCCCOCCC#Cc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccnc(C#N)c3)n2)CC1 +Nc1ccccc1NC(=O)C=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cc1 +CC(C)NC(=O)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 +Cc1cccc(-c2[nH]c(CNc3cc(C#N)cc(N(C)C)c3)nc2-c2ccc3ncnn3c2)n1 +NC1=NC(c2cccc(Oc3cccc(C(F)(F)F)c3)c2)N(c2cccc(Cl)c2)C(N)=N1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1cccc(C(F)(F)F)c1 +N=C(N)c1ccc(C(=O)NCC(=O)N2CCN(CCC(=O)O)C(=O)C2CC(=O)O)cc1 +N#CCNC(=O)C1CCCCC1C(=O)N1CCc2ccccc2C1 +CCCOc1ccc(-c2cn(-c3nc(NC)c4ncn(C5OC(CO)C(O)C5O)c4n3)nn2)cc1 +O=C(NC1CCS(=O)(=O)CC1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +Cc1cc(C(=O)O)ccc1-c1ccc2c(c1)CC(NCC(O)c1ccc(Cl)cc1)CC2 +CC(NC(=O)Nc1cccc(-c2nnnn2C)c1)C(O)CN(C)CCCc1ccc(F)cc1 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+O=C(NCCc1ccc(CN2CCCC2)cc1)c1ccc(-c2ccc(F)cc2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CC=C(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C=Cc1ccccc1 +COCCNC(=O)C1CC(Sc2nc3ccccc3[nH]2)CN1Cc1ccc2ccccc2c1 +CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1cc(OC(F)(F)F)ccc1n2CCF +O=C(NCC(F)(F)F)C1CN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)C1 +CC(=O)Nc1ccc(Sc2nc(Nc3cc(C)n[nH]3)c3ccccc3n2)cc1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCc4[nH]ncc4C3)cc2F)cn1 +[C-]#[N+]C1=C(C(F)F)Nc2onc(C)c2C1c1cc2c(C)n[nH]c2cc1F +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCCCCCNC(=O)C=Cc2ccc(Cl)cc2)C1 +CCN(CC)CCOc1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(C(C)C)no2)n1 +CNC(=O)CN1CCC(Oc2cc3c(Nc4cccc(Cl)c4)ncnc3cc2OC)CC1 +Cc1ccc2sc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)nc2c1C +COc1ccc(CNCCc2cc(OC)c(NC(=O)Nc3cnc(C#N)cn3)cc2Cl)cc1 +O=c1[nH]nc2[nH]c(CN3CCN(c4ccncc4)CC3)nc3cccc1c32 +COC(=O)C1CCN(C(=O)NC2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)CC1 +O=C(CCc1ccc(-c2ccccc2)cc1)N1CCCC1c1ncc(-c2cccc(F)c2)[nH]1 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+OCC(O)C(O)C(O)C(O)C[S+]1CC(O)C(O)C1CO +O=c1cc(CSc2ccc(C(F)(F)F)cn2)c2ccc(O)cc2o1 +CC(CO)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2)cc(C(=O)Nc2cc[nH]n2)c1 +COc1cnc(NC2=NCC3(CN4CCC3CC4)O2)cn1 +Cc1nncn1C1CCN(Cc2cc3nc(-c4cccc(O)c4)nc(N4CCOCC4)c3s2)CC1 +CSc1nc(-c2ccc(Cl)cc2)nn1C(=O)N(C)c1ccccc1 +C=CC(=O)Nc1cccc(CNc2c(C(N)=O)cnn3cccc23)c1 +CCCCCOc1ccc2cc(-c3noc(C4CCCN4C(=N)N)n3)ccc2c1 +Cc1ccc(C(C)Nc2nc3cc(F)ccc3o2)cc1NC(=O)c1cnc2ccccn12 +N=C1NC(c2ccccc2)(c2cccc(Oc3ccccc3)c2)C(=O)N1C1CCCCC1 +CCCCCS(=O)(=O)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1 +CC(CC#CC(C)(C)O)C1CCC2C(=Cc3ccc(CO)c(CO)c3)CCCC21C +Cc1cccc2cc3cccc(C(=O)NCCCN(C)CCCNc4n[n+]([O-])c5ccccc5[n+]4[O-])c3nc12 +CCN(CCCCCC1Cc2cc(OC)c(OC)cc2C1=O)Cc1ccccc1OC +CC(C)Oc1cc(-c2ccc(CCNC(C)C(O)c3ccccc3)cc2)ccc1C(=O)O +C=CCn1cc(C2=NCC3(CN4CCC3CC4)O2)c2ccccc21 +Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1nc2cc(N3CCCC3)ncc2[nH]1 +Nc1ncc(Cc2ccc(OCCCOCCCOc3ccccc3)cc2)c(N)n1 +O=C(CCN1CCN2Cc3ccccc3CC2C1)Nc1ccccc1Cl +CC1(COc2ncc(C(F)(F)F)cn2)Cn2cc([N+](=O)[O-])nc2O1 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+CN1C(=O)C2(CC(C)(C)Oc3ccc(-c4cncc(F)c4)cc32)N=C1N +CCCCC(CCCC)Nc1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +N#Cc1ccc(NS(=O)(=O)c2ccccc2C#N)cc1Cl +CC1(c2ccc(-c3ccc4ccccc4c3)[nH]c2=O)OC(=O)NC1=O +O=C1Cc2c(OCCN3Cc4ccccc4C3)ccc(Cl)c2N1 +CN1CCN(c2ccc3nc(Nc4ccc(Br)cn4)[nH]c3c2)CC1 +N#CC(c1cccnc1)N1CCN(C(=O)Cc2ccc3ccccc3c2)CC1 +CCc1nnc(-c2ccc(-c3ccccc3)cc2)n1-c1cccc2cccnc12 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(C[n+]3ccccc3)cc2)C1O +COc1cc(OC)cc(C(=O)OC2C=CC(=O)C3(CC(=O)OC3C=C(C)CCC=C(C)C)C2)c1 +Cc1cccc(NC(=O)c2c(NO)cc(-c3ccccc3)oc2=O)c1 +COc1cc(OC)nc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(C#N)c3)cn2)n1 +CCC12CCC(=O)C(C(F)(F)F)=C1c1ccc3[nH]nc(F)c3c1C2 +Cn1c(=O)n(Cc2ccccc2Cl)c2c(N3CCCC(N)C3)ccnc21 +N=C(N)c1ccc(OC(=O)c2ccc(CC3(C(=O)NC(CC(=O)O)C(=O)O)CCC3)s2)c(F)c1 +COc1ccc(Cn2cc(C(=O)Nc3cc(C=Cc4cc(OC)c(OC)c(OC)c4)cc(OC)c3OC)nn2)cc1 +Cc1c(C(=O)Nc2ccccc2F)nnn1-c1ccc(C(C)C)cc1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(C(F)(F)F)cc4)cn3CCN3CCCC3)CC2)c1C1CCC1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=NC#N)cc2)cn1C(C)C +O=C1N(Cc2ccc3ccccc3c2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1CC1CC1 +CC(C)CC(CO)Nc1nc(SCc2cccnc2)nc2nc(N)sc12 +O=C(O)Cc1ccc(Nc2nc(-c3ccccc3)nc3ccccc23)cc1 +CCCN(CCCCOc1ccc2c(C=O)cnn2c1)C1CCc2c(O)cccc2C1 +COc1cnc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)C(C)(F)CC3(F)F)c2)c(C)n1 +CC(NC(=O)C(F)(F)F)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1cnc2ccccc2c1 +CCC12CC3CC(C1)CC(NCC(=O)N1CCCC1C#N)(C3)C2 +Nc1nc(NCC2CCCN2Cc2c(F)cccc2F)nc2nc(-c3ccco3)nn12 +CCCCCN(C(C)=O)c1ccc(NC(=O)C2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 +O=C1C(=Cc2cccc(O)c2)CSCC1=Cc1cccc(O)c1 +CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(C#C[Si](C)(C)C)ccc1-2 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3Cl)nc12)N1CCOCC1 +COC(=O)C1CC(OC(=O)C=Cc2ccccc2)CN1S(C)(=O)=O +COc1cccc(OC)c1OC1CCC(NCC2COc3ccccc3O2)C1O +CCNC(=O)Nc1nc2cc(-c3cnc(C(C)(C)O)nc3)c(F)c(C3CCCO3)c2[nH]1 +CCOC(=O)CCc1cnccc1N1CCC(COc2ccc3c(c2)CN(C(=N)N)CC3)CC1 +CC(=O)NC(C)C(=O)NN=CC(Cc1ccccc1)NC(=O)c1ccccc1 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+Cc1ccc2c(c1)c(C#N)cn2-c1ccc(C(=O)O)cn1 +CCC1OC(c2ccc(Cl)c(Cc3cnc(-c4ccccc4)nc3)c2)C(O)C(O)C1O +Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CCN1CCCCC21 +Clc1ccc(C2=CC3CCC(C2)N3CCOc2cccc3[nH]ccc23)cc1Cl +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(nnn2-c2ccccc2)C1 +CC(NC(=O)c1cn[nH]c1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 +CCOC(=O)C(C)(C)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +O=c1c(NCC2CCOCC2)nc2ccc(-c3ccncc3)nc2n1CC1CCCCC1 +COC(=O)c1cc(-c2ccc(S(N)(=O)=O)cc2)c(-c2ccc(F)cc2)s1 +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1Cc1cn[nH]c1 +O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccc(N4CCCC4)cc3)ncnc2s1)NO +CC(=O)NCCOc1ccccc1C(=O)NCCCCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O +O=C(C=Cc1ccc2c(c1)ncn2Cc1ccccc1)NO +COc1ccccc1N1CCN(CNC(=O)c2ccc(C)cc2)CC1 +CCn1nc(C(F)(F)F)cc1C(=O)Nc1cccc(C(C)Nc2ncnc3c(C(N)=O)cccc23)c1 +CCCOc1ccc(C23c4ccccc4C(=O)N2CCN3C(=O)c2ccc(F)cc2)cc1 +COc1ccc2nc(NC(Cc3ccc(C4CC(=O)NS4(=O)=O)cc3)c3nc4ccccc4[nH]3)sc2c1 +CC(C)Cc1ccccc1C(=O)N(CCc1ccc(Cl)cc1)C1CCC2(CC1)OCCO2 +CC(C)(C)C1CCC(C(=O)N2CCc3cc(S(=O)(=O)Nc4ccc(CCCC5CCCC5)cc4F)ccc3C2)CC1 +COc1ccc(NC(=O)CC2(CC(=O)NC3C4CC5CC(C4)CC3C5)CCCC2)cc1 +O=C(CCCn1c(=S)[nH]c2ccccc2c1=O)N1CCN(Cc2cccc3ccccc23)CC1 +CN(C)CCCNC(=O)Cn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(C)c4)cc2)CC3)n1 +CC1=CSC(O)(c2ccc(C)cc2)c2noc(=O)n21 +Clc1ccc2c(NCCCn3cnc4c(N5CCSCC5)nc(Cl)nc43)ccnc2c1 +COc1ccc(OCC(=O)N2CCC3(CC2)CN(Cc2ccc(-n4nccn4)cc2)C3)cc1 +COc1ccc2c(c1OC)CN(C)CCc1cc3c(cc1C(=O)C2)OCO3 +O=C(c1ccccc1)N1CCC2(CC1)CC(C(=O)N1CCN(C3CCC3)CC1)C2 +Fc1ccc(OCc2cc(OCC3COC3)nc(-c3ccccn3)n2)c(F)c1F +COc1ccc(COc2nn3c(-c4ccccc4)nnc3c3ccccc23)cc1 +C(#Cc1nc2ncccc2nc1OCCc1ccccn1)c1ccccc1 +CC(C)=CCn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc21 +O=C1CC(O)CC(C=Cc2c(F)cc(F)cc2-c2ccc(F)cc2)O1 +O=C(NCC1CCCNC1)c1ccc(O)c2[nH]c(Cc3cccs3)nc12 +CNc1nc(Nc2cc3c(cc2OC)C(=O)N(CC(C)(C)O)C3)ncc1C(F)(F)F +CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCNCC3)c2)ncc1Cl +Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +COc1cccc(-c2cccc(CCC3(C)CC(=O)N(C)C(N)=N3)c2)c1 +COC(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3F)ncc12 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C)CCC2 +CCC(=O)Oc1cc(C=CC(=O)c2ccc(OC)c3c2OC(C)(C)C=C3)ccc1OC +Cc1nc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC(C)N(CC4CCOCC4)CC2C)C3(C)C)c(C)o1 +COc1cccc(OC)c1-c1ccc(CC(NC(=O)C2(C)OC(C)CC2=O)C(=O)O)cc1 +O=c1c2cnc3ccc(Br)cc3c2[nH]n1-c1ccccc1 +CN1C(=O)Cn2c(=O)n(CC(=O)Nc3ccc4c(c3)CC3(C4)C(=O)NC(=O)N3C)c3cccc1c32 +CC12CCC3c4cc([N+](=O)[O-])c(O)cc4CCC3C1CCC2NS(=O)(=O)c1cccc(Br)c1 +CC#CCn1c(N2CCNCC2)nc2c1c(=O)n(Cc1ccc3ccccc3n1)c(=O)n2C +CN1C2CCC1CC(OC(=O)c1nn(CC(F)(F)F)c3ccccc13)C2 +O=C1Nc2cccnc2N(C(=O)CN2CCNCC2)c2ncccc21 +CC1CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)=CC(O)C1 +O=C(NC1CC(O)c2ccccc21)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F +CC1(C)Oc2nc(C(F)(F)F)nc(N)c2N=C1c1ccc(C2CCC(CC(=O)O)CC2)cc1 +Nc1ncnc2c1ncn2C1OC(CO)C(OC2OC(CO)C(OP(=O)(O)O)C(OP(=O)(O)O)C2O)C1O +CCOC(=O)C=CC(CCC(N)=O)NC(=O)C(CC(=O)C(NC(=O)SCc1ccccc1)C(C)C)Cc1ccccc1 +CC1(O)CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)CC1 +c1ccc(Nc2nc3c(N4CCOCC4)ncnc3s2)cc1 +CC#Cc1cncc(-c2cccc(C3(C4CC4)NC(=N)N(C)C3=O)c2)c1 +CN1CCN=C1c1cccc(Oc2cc(C(=O)O)cc(Oc3cc(C(=N)N)ccc3O)n2)c1 +CCCCCCCCCCCCCCOc1cccc(OP(=O)([O-])Oc2cccc(C[n+]3ccsc3)c2)c1C(=O)OC +C#CCCCON=c1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)[nH]1 +O=C(COC(=O)c1ccc2c(c1[N+](=O)[O-])C(=O)c1ccccc1C2=O)NC1CC1 +COc1cc2c(cc1OC)CN(Cc1cnc(N)n3nc(-c4ccco4)nc13)CC2 +CC(C)c1cc(Oc2c(Br)cc(CC3NC(=O)NC3=O)cc2Br)ccc1O +CC(NC(=O)c1cc2c(c(C(=O)NC(Cc3ccccc3)C(O)CNC3CC3)c1)CCCO2)c1ccccc1 +COc1ccc(F)cc1Oc1ccc(C(F)(F)F)cc1C(=O)Nc1cc[nH]c(=O)c1 +CC1CCCN1C1CCC(c2ccc(NC(=O)C3CCOCC3)cc2)C1 +COc1cc(Nc2ncc(-c3ccccc3N(C)C(=O)CN3CCOCC3)o2)ccc1-c1cocn1 +CC1=CC(C)(C)Nc2ccc3c(c21)Cc1cc([N+](=O)[O-])ccc1-3 +N#CCC(=O)Nc1ccc(Cl)c(-c2nc3cc(Cl)ccc3o2)c1 +COCCOc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +COc1cc2c(cc1OC)C(c1ccc(F)cc1)N(C(=O)c1ccc(S(N)(=O)=O)cc1)CC2 +Clc1ccc(-c2ccc(-c3nc4ccccc4n3-c3ccc(N4CCNCC4)cc3)o2)cc1 +COCCNCc1c(C(N)=O)nc2n1C1CC(C1)c1cc(F)c(C#CC(C)(C)O)cc1-2 +O=C(CCCCCCCn1cc(-c2cccc(-c3ccccc3)c2)nn1)NO +COCC1CCCN1C(=O)c1cc(N)n2nc(-c3ccc(Br)o3)nc2c1 +N#Cc1ccccc1C(=O)Nc1cccc(CNc2ncnc3c(C(N)=O)cccc23)c1 +CN(Cc1ccccc1)C1C2C3CC4C2C(=O)C2C4C3C21 +CC(C)CC(NC(=O)OC(C)(C)C)C(=O)NCC#N +CCN(CC)C(=O)c1ccc2c(c1)nc(Cc1ccc(OC(F)(F)F)cc1)n2CCC(C)C +CC(C)COc1ccc(-c2n[nH]c(-c3ccncc3)n2)cn1 +Cc1ccc2[nH]c(NC3CN(C(=O)OC(C)(C)C)CC3OC(=O)c3cccc(-c4ccc(F)cc4)c3)nc2c1 +O=C(c1ccc(N2CCN(Cc3ccccc3)CC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +NCc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F +CNC(=O)c1ccc2c(c1)nc(-c1ccccc1)n2C1CCCC(NC(=O)c2ccc(Br)s2)C1 +Cn1cncc1CNc1cc2c(cc1Cl)NC(=O)Nc1cnc(C#N)c(n1)OCCCCCO2 +Cn1c(=N)n(CCOc2ccc(-c3ccccc3)cc2)c2ccccc21 +COC(=O)Nc1ccc2c(c1)NCCCC=CCC(NC(=O)C=Cc1cc(Cl)ccc1-n1cnnn1)c1nc-2c[nH]1 +N#Cc1ccc(C(=O)NC2CCC(CCN3CCC(c4coc5ccccc45)CC3)CC2)cc1 +Cc1nc(-c2ccc(Cl)s2)c(-c2ccc(S(C)(=O)=O)cc2)o1 +Cc1cc(OC(F)(F)F)ccc1NC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 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+CC1NC(=O)C(C(C)C)NC(=O)CC(CCCCCC(=O)O)NC(=O)C(Cc2ccccc2)NC1=O +O=C(O)c1c(F)cc(F)cc1-c1ccc2c(c1)OCC(Cc1ccccc1)C2O +Cc1cc(-c2cc(-c3ccccc3)cc(N(C)Cc3ccccc3)n2)ccc1O +O=[N+]([O-])c1cc(Br)c2nc3ccccc3nc2c1 +N#CC(Cc1ccc(-n2cc(-c3ccc4occc4c3)nn2)cc1)NC(=O)C1NC2CCC1C2 +CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(=O)c3ccc(C(=O)O)cc3)c3cc(C(=O)O)ccc32)cc1 +CSc1ccc(-c2nc(-c3cccc(N)c3)c(-c3ccncc3)[nH]2)cc1 +CC(=O)CSc1ccc(-c2nc3cc(C)c(C)cc3[nH]2)cn1 +O=C(Nc1c[nH]nc1-c1nc2cc(CN3CCOCC3)ccc2[nH]1)Nc1c(F)cccc1F +c1ccc(-c2cn3ccnc3nc2-c2ccc(CN3CCC(c4nc5cccnc5[nH]4)CC3)cc2)cc1 +O=C(Nc1cc2cc[nH]c(=O)c2cc1Cl)C1CNCC1c1cccnc1 +O=C(Nc1ccc(Cl)nc1)c1cccc(C(F)(F)F)c1 +COC1CCC(C(=O)c2ccc3nc4c(cc3c2)CCS4)CC1 +CC(C)=CN1Cc2cc(Cl)cc3[nH]c(=O)n(c23)CC1C +Cn1cc(-c2cccc3ccccc23)cc1C(=O)N1CCC(CO)CC1 +FC(F)(F)CN=CNc1ccc(-c2c[nH]cn2)cc1 +CC(NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1)(C(=O)Nc1ccccc1)c1ccc(C(N)=O)cc1 +COc1cccc(CNC(=O)c2cc3ccc(-c4cn[nH]c4)cc3n2CCCO)c1 +NC1CCCCC1Nc1cc(-c2cccc(NCc3cccc(F)c3)n2)c(Cl)cn1 +O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCCCC4COC4)cc3)cc12 +CC(C)(C)NC(=O)C1CCCCN1CC(O)C1Cc2ccc(cc2)OCCCC(=O)NC(CC(N)=O)C(=O)N1 +O=c1[nH]c(Cc2ccccc2-c2ccncc2)nc2c1cnn2C1CCOCC1 +Cn1cnc(S(=O)(=O)n2ncc3c2CN(C2COC(c4cc(F)ccc4F)C(N)C2)C3)c1 +COc1ncc(Nc2ncc(C(C)N3CCN(S(C)(=O)=O)CC3C)cc2-c2nc(C)nc3[nH]cnc23)cc1F +C[n+]1cn(-c2ccc(-c3ccc(-n4c[n+](C)c5ccccc54)cc3)cc2)c2ccccc21 +COc1ccc(Sc2ccc(F)cc2CSC(=N)N)c(CSC(=N)N)c1 +CNc1cccc(CN2C(=O)N(Cc3ccc4[nH]ncc4c3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)c1 +COC(=O)c1c(C)n(C)c2ccc3c(c12)CN1CCc2cc(OC)ccc2C1O3 +O=C(Nc1ccccc1)c1ccc(-c2cc3ccncc3cc2OC2CCNCC2)s1 +COc1ccc2c3c(c(=O)oc2c1)CN(C(=O)c1ccccc1)CC3 +CN(CCCCCCC(=O)NO)C(=O)c1ccc(N(C(=O)c2ccccc2)c2ccccc2)cc1 +O=[N+]([O-])c1ccc(S(=O)(=O)N2CCC(CCN3CCC(c4noc5cc(F)ccc45)CC3)CC2)cc1 +C(=CC1CCCN(CCCOc2ccccc2)C1)c1ccccc1 +O=C(O)c1cc(-c2cccc3cccnc23)nc2c1cnn2Cc1ccncc1 +CNCCNc1cnn(Cc2cccc(NC(=O)c3ccc(-c4ccc(OC)nc4)cc3)c2C)c(=O)c1Cl +O=C(NCc1csc2ccccc12)c1nc(-c2cccs2)nc(O)c1O +O=C1Nc2c(Cc3ccccc3O)ccnc2N(C2CC2)c2ncccc21 +Cc1nnc2c3ccccc3c(-c3ccc(N4CCOCC4)c(NS(=O)(=O)c4ccc(Cl)cc4)c3)nn12 +CC(C)(C)c1cccc(NC(=O)c2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)c1 +CC(C)(C)c1ccc(C=CC(=O)Nc2ccc3c(c2)OC(CO)CO3)cc1 +NC(Cc1ccc2ccccc2c1)C(=O)NCC(=O)Nc1c2c(nc3ccccc13)CCCC2 +CC(C)CC(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)CNC(=O)NCC(F)(F)F +O=C1OC2(CCNCC2C(=O)N(Cc2cccc(C(F)(F)F)c2Cl)C2CC2)c2cc(F)c(F)cc21 +CN(C)C(=O)c1cc2ccc(Nc3nccc(-c4cc(OC5CCC(=O)NC5)ccn4)n3)cc2n1C +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CCC(=O)N2CCOCC2)CC1OC +CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3ccccc3)c(Oc3ccc(C(F)(F)F)cc3)s2)cc1 +N#Cc1ccc(NC(=O)c2csc(Cc3c(Cl)cccc3Cl)n2)cc1 +Cc1cc(OC2CNC(C(=O)N3CCCN(C4CCC4)CC3)C2)ccc1Cl +O=C(c1cccnc1)N1CCc2nc(Nc3ccsc3)ncc2C1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(F)c(Cl)c3)CC2)nc1-c1cc[nH]n1 +O=C1CC(c2ccc(O)c(-c3c(O)cc(O)c4c3OC(c3ccc(O)cc3)CC4=O)c2)Oc2cc(O)cc(O)c21 +Cc1ccc(C2=CCC(C)(C)c3ccc(C#Cc4ccc(C(=O)O)cc4)cc32)cc1 +COc1cc(OCc2csc(N3CCN(Cc4cccnc4)CC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +CCc1nc2c(C)cc(C)nc2n1Cc1cc(Br)c(O)c(Br)c1 +CON=C(C)c1ccc2ncc(Cc3ccc4ncccc4c3)n2n1 +CCN(CCN1CCOCC1)c1cn(-c2ccc(Cl)c(Cl)c2)nn1 +CC(=O)c1ccc(NC(=O)Nc2ccc(-c3nc(N4CCOCC4)c4ncccc4n3)cc2)cc1 +COC(=O)C(Cc1c(Sc2ccccc2[N+](=O)[O-])[nH]c2ccccc12)NC(=O)C(O)C(N)CCCCN +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NS(=O)(=O)CCN(C)C)no2)cc1C#N +COc1cc(NC(=O)c2ccc(-c3cccc(C(F)(F)F)c3)cc2)ccc1OCCN(C(C)C)C(C)C +CON=C1CCC(N(C(=O)C2CCC(C)CC2)c2cc(C#CC(C)(C)C)sc2C(=O)O)CC1 +CCOC(O)=C1C(C)=NC(c2ccccc2)=C(C(=O)OCc2ccc(C)cc2)C1C#Cc1ccccc1 +CCOC(=O)NC1CCc2ccc(OCCNS(=O)(=O)c3cn(C)cn3)cc2C1Cc1ccc(Cl)c(Cl)c1 +CNc1nc(N2CCOCC2C)c2ccc(-c3ccc(OC)c(CO)c3)nc2n1 +N#Cc1cc(NC(=O)c2ccc(-c3noc(C(F)(F)F)n3)cc2)ccn1 +Oc1ccc(C2=NN(c3cccc(Cl)c3)C(c3ccc(O)c(F)c3)C2)c(O)c1 +Clc1ccc2c(NCc3nc4ccccc4[nH]3)ccnc2c1 +CC(C)CCN1C(=O)C(NC(=O)Oc2ccccc2)C(=O)N(CC23CC4CC(CC(C4)C2)C3)c2ccccc21 +Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CCC3CN4C(=O)c3cccnc3)nc21 +COc1cc(-c2cnc(C)nc2OCC2CC2c2ccc3ccccc3n2)cn(C)c1=O +N#Cc1ccc(Cn2cncc2CN2CCN(C(=O)c3ccccc3-c3ccccc3)CCC2c2ccccc2)cc1 +COc1cc2c(cnc3[nH]ncc32)cc1-c1c(F)ccc(NS(=O)(=O)CCCF)c1Cl +CCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(C)c2)c(-c2ccccc2)c1 +O=C(O)c1ccc(Cn2nnc(-c3ccnc(C(=O)NCc4ccc(F)cc4)c3)n2)cc1 +CCCC1COc2c(ccc3[nH]c(=O)cc(C(F)(F)F)c23)N1 +NC1=NC(c2cc(NC(=O)c3ccc(OC(F)F)cn3)ccc2F)(C(F)F)COC1 +OC12C3C4CC5C6C4C1C6C(C53)N2Cc1ccccc1 +N#CC1(CNc2nc(-c3cc(NC4CCC(N)CC4)ncc3Cl)ccc2F)CCOCC1 +O=C(O)c1csc(-n2nc(-c3ccsc3)c3ccccc32)n1 +CCCCCn1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)cc1-c1ccccc1 +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCCC(N)C4)c23)c1 +O=[N+]([O-])c1ncn(CCCNCc2ccc(C(F)(F)F)cc2)n1 +CC(C)c1cc(C(F)(F)F)nc(NNc2nc(C(C)C)cc(C(F)(F)F)n2)n1 +OCCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1 +O=C1Nc2c(Cl)cccc2C1=Cc1ccc(-c2cccc(C(=O)NCCN3CCCC3)c2)o1 +COc1ccccc1C(O)c1ccc(-c2nc3cc(C(N)=O)ccc3[nH]2)cc1 +CC1Cc2cc(O)ccc2C(c2c(F)cc(C=CC(=O)O)cc2F)N1CC(C)(C)F +CCN(c1nc(C)cc(-c2ccccc2F)n1)c1ccc(C(C)C)cc1Br +Cc1cccc(C)c1Sc1[nH]c2nc(N)nc(N)c2c1C(C)C +CC1(C)Cc2nc(C3CCCC3)c(C(F)c3ccc(C(F)(F)F)cc3)c(-c3ccc(F)cc3)c2C(O)C1 +N#Cc1c(NC(=O)c2cc(S(=O)(=O)N3CCOCC3)c(Cl)cc2Cl)sc2c1CCC(c1ccccc1)C2 +O=C(NS(=O)(=O)c1cccs1)c1ccc(Cl)cc1Cl +Cn1c(=O)c2c(nc3n2CCCN3c2ccc(F)cc2)n(C)c1=O +NC(=O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O +Cc1cccnc1-c1nc(N2CCC(CS(C)(=O)=O)CC2)ncc1Cl +Cc1cc(C)c(-n2c(Cl)cn3c(CN(CCc4ccccc4)CC(F)(F)F)c(C(F)(F)F)nc23)c(C)c1 +CCCCCCCCCCC(=O)Nc1ccn(C2OC(CO)C(O)C2(F)F)c(=O)n1 +CC(C)(C)NC(=O)C(C1CC1)N1C(=O)c2cc(O)ccc2NC(=O)C1CCCCN +N#Cc1ccc(COc2ccc(Br)cc2C(=O)Nc2cccnc2)cc1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC2CCN(C(=O)N3CCC3)CC2)c2ccccc12 +Cc1ncccc1NS(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl +CCc1ccc(CCc2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)cc1 +NCCNc1nc(NCCO)nc(Nc2ccc(CCNc3nc(NCCO)nc(Nc4cccc(N)c4)n3)cc2)n1 +COC(=O)Nc1nc2cc(Oc3cc(OC)cc(OC)c3)ccc2[nH]1 +Cn1nccc1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCC(O)CC1 +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCCCCCCCCCCCCNc4c5c(nc6ccccc46)CCCC5)c3C(C1)C2 +COc1ccc2cc(CNCc3ccc(C)cc3)c(-c3ccsc3)nc2c1 +Cn1cc(CN2C3CCC2CC(Oc2cccc(C(N)=O)c2)C3)cn1 +COc1ccc2c(Oc3ccc(NC(=O)c4c(C5CCCN5)n(C)n(-c5ccccc5)c4=O)nc3)ccnc2c1 +CCN1CCN(c2nc(Nc3ccccc3)n3ncc(C#N)c3n2)CC1 +CCn1cnc2c(Nc3ccc(OC)cc3)nc(NCCN)nc21 +O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2)c2ccccc12 +Cn1cc(-c2cccc(N3CCn4c(cc5c4CCCC5)C3=O)c2CO)cc(Nc2cc3n(n2)CCOC3)c1=O +CN1CCN(C(=O)CNC2CC2c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)CC1 +O=C(NN=Cc1c(O)ccc2ccccc12)c1ccccc1 +Cc1ccc(Cn2c(=Nc3ccc(OC(C)C)c(C)c3)[nH]c(=O)n(CCCC(=O)O)c2=O)cc1 +CCN1C(=CC=c2sc(=Cc3sc4ccccc4[n+]3CC)n(C)c2=O)Oc2ccccc21 +CCCc1cc(N)c2cc(NC(=O)C=Cc3ccc(Cl)cc3Cl)ccc2n1 +Cn1cncc1C(O)(c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1)C1CC1 +COc1ncccc1CN(C(=O)CF)c1ccccc1Oc1ccccc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1ccc(Cl)nc1 +CCc1cccc(NC(=O)Nc2cc(Cl)cn(Cc3ccccc3Cl)c2=O)c1 +COc1ccc(CNC2CCC3(CC2)OC(OC)Cc2ccccc23)cc1 +Cc1ccc(S(=O)(=O)NC(CNC(=O)c2ccc3oc(-c4ccc(C(=N)N)cc4)nc3c2)C(=O)O)cc1 +CCNC(=O)Nc1ccc2ncc(-c3cnn(C)c3)nc2n1 +CN1CCN(C2=C(Cl)C(=O)N(c3ccc(Cl)c(Cl)c3)C2=O)CC1 +CCN(CC)C(=O)C1CCC2C3CN(Cc4ccccc4)C4=CC(=O)CCC4(C)C3CCC12C +Cn1ccnc1COc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl +COc1c(C)c(C)c(Cl)c(N)c1CC=C(C)CCC(=O)O +CC1CCC(Oc2cc(C#N)ccn2)CN1C(=O)c1cccc(F)c1-n1nccn1 +COc1cc(OC(C)C)c2cc(-c3cn4nc(Br)sc4n3)oc2c1 +NC(=O)c1cc(N(CCOS(N)(=O)=O)CCOS(N)(=O)=O)c([N+](=O)[O-])cc1[N+](=O)[O-] +COc1ccc(-c2nn3c(N)nc4ccccc4n3c2=O)cc1 +O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(-c3ccccc3)cc2)(c2ccccc2)n2nnc3ccccc32)cc1 +CC(C)N1CCN(C(CN2CCN(CCCc3ccccc3-c3ccc(-c4ccccc4)cc3)CC2)c2ccc(F)cc2)CC1 +CN(C)CCOc1ccc(C(=C(CCCl)c2ccccc2)c2ccccc2)cc1 +CCC(C)C(NC(=O)C(S)C(C)C)C(=O)N1C(C(=O)O)CC2CCCCC21 +O=C(NCc1cn(-c2ccccc2F)c2cc(F)ccc2c1=O)c1ccc(Cl)nc1 +CCCCNc1cccn2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nc12 +O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)N[n+]2ccc3ccccc3c2)cc1 +COc1ccc(CC2CC(C)(C)N(C)C(C)(C)C2)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1 +COc1ccc2[nH]cc(CCNC(=O)CCc3cc[n+](Cc4ccccc4F)cc3)c2c1 +COc1ccc2cc(C(C)(O)CCN3CCCCC3)ccc2c1 +CC(C)(C)C(=O)Oc1coc(CSc2nc3ccccc3o2)cc1=O +CCc1nc2c(-c3ccc(OC)nc3C)ccnc2n1C(CC)C1CC1 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+CS(=O)(=O)Nc1ccc2ccc3ncc(-c4ccccc4)cc3c(=O)c2c1 +CCC(C)Sc1ccc(-c2nc3ccc(C)cn3c2NC2CCCCC2)cc1 +NC1=NC(c2ccco2)NC(NCCCOc2ccc(Cl)cc2)=N1 +CC(CN)c1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4sccc4c23)cc1 +C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(C=NOCCO)c(F)c2F)c(F)c1 +CC(C)C(=O)OCC(C)(C)CC1=C(O)C(=O)c2ccccc2C1=O +CN(C)C(=O)CN(C)C(=O)C1CCc2c(sc3ncnc(Nc4ccc5[nH]c(=O)sc5c4)c23)C1 +CC(=O)C1CCC2C3CCC4N(C)C(=O)CCC4(C)C3CCC12C +Cc1cc(-c2ccccc2)cc(C)[n+]1CC(=O)Nc1ccc(S(N)(=O)=O)cc1I +COc1cccc(OC)c1C(=O)Nc1c[nH]nc1C(=O)NC1CC2CCC1C2 +CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3ccccc3)c(Oc3ccc(Cl)cc3)s2)cc1 +CC1COCCN1c1nc(N2CCOCC2)nc2[nH]c(-c3cnc4cc[nH]c4c3)nc12 +CN(CCCNc1nc2ccc(Cl)cc2n2cccc12)CCCNc1nc2ccc(Cl)cc2n2cccc12 +N#Cc1ccc(C(=O)Nc2cc(-c3ccccc3)nn2-c2ccccc2)cc1 +O=S(=O)(c1cccc(C(F)(F)F)c1)c1sc2ncccc2c1-c1ccc(Cl)cc1 +CCCC#Cc1ccc(C(CO)NC(=O)C2CC2c2cccs2)c(OC)c1 +NC(C=C(CCCCCCNC(=O)c1ccccc1)CP(=O)(O)O)C(=O)O +COc1ccccc1N1CCN(CCCN2CC(=O)N3CCCCC3C2=O)CC1 +CCc1nccc(-c2ccc(C3CC3)nc2)c1C#Cc1ccc(N)nc1 +O=c1ccc2ccc(OCC(=NO)c3ccc(F)cc3)cc2[nH]1 +COc1ccc2nc3cc(Cl)ccc3c(NCCCCNCCCCCNCCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1 +CCc1cc(CN2CC(C(=O)O)C2)sc1-c1noc(-c2ccc(Oc3ccccc3)c(F)c2)n1 +O=C(C=Cc1ccc(Br)cc1)Nc1ccc2c(c1)OCCO2 +Cc1ccc(-c2cc3c(N=O)c4ccccc4c-3[nH]n2)cc1 +Cc1ccc2c(c1)OC1c3[nH]c4ccc(O)cc4c3CCN1C2=O +COCCCNc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n3n2CCC3)n1 +CC(N)C(=O)NCc1cccc(-n2nc(C(F)(F)F)cc2-c2nnc(Cc3ccccc3)o2)c1 +CC(C)NC(=O)N1CC2CC(NCC(=O)N3CCCC3C#N)CC2C1 +O=C(Nc1ccc(N2CC(F)(F)C2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F +COc1cc(CNC(=O)C#Cc2cn(Cc3ccc(C(=O)NCCO)cc3)c(=O)[nH]c2=O)ccc1F +CNC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C(F)(F)F)nc1 +COCCOc1ccc(F)c(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(OC(F)(F)F)c2)c1 +COc1ccc(CC(NC(=O)CCc2nc[nH]c2C)C(=O)N2CC(OCC3CC3)(c3ccccc3C)C2)cc1 +Clc1cc(Cl)c(OC2CC2)c(CNC2CCCN(c3nc4nc(Cl)ccc4[nH]3)C2)c1 +CSc1ccc(S(=O)(=O)CC2CCCCC2NC(=O)CNC(=O)c2cc(C(F)(F)F)ccc2NC(=O)N(C)C)cc1 +CN1CC(C(=O)c2ccccc2Cl)C(c2ccc(Cl)cc2)C1 +CCc1cc(-c2ccccc2)cc(CC)[n+]1CC(=O)Nc1ccc(S(N)(=O)=O)cc1 +COc1cc2ncnc(NC3CC3c3ccccc3)c2cc1OC(C)=O +CCc1cc2c(s1)Nc1ccc(F)cc1N=C2N1CCN(C)CC1 +O=C(C1CNCCC1(O)c1ccc(F)c(F)c1)N(Cc1cn(Cc2ccncc2)c2cccc(F)c12)C1CC1 +CC(C)Oc1ccc(-c2cc(NC(=O)C3Cc4ccccc4C3)[nH]n2)cc1 +CN1CCN(c2ccc(-c3cnc4c(c3)N(Cc3cc(Cl)ccc3C(F)(F)F)CCN4)cn2)CC1 +CCN(CC)CCCNC(=O)C(Cc1ccccc1)NC(=O)C1(NC(=O)c2cc3ccccc3s2)CCCCC1 +COc1cc(NC(=O)c2ccncc2)c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(CCc3ccc4ccccc4n3)cc12 +COc1ccc2[nH]cc(CCn3cnc(NC(=O)c4ncoc4-c4cccc(C)c4)c3)c2c1 +NS(=O)(=O)OCCCCCCCCCCCCCCCCOS(N)(=O)=O +COc1ccc(-c2nc(C=C3SC(=S)NC3=O)cs2)cc1 +CNC(C)(C)c1nc(O)c(O)c(C(=O)NCc2ccc(F)cc2)n1 +Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(Br)cc(C(=O)O)c1 +C=CC(=O)Nc1ccc2c(c1)CCCc1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn1-2 +CN(C)c1ccc2c(CC(=O)OC3CC(=O)c4coc5c4C3(C)c3ccc4c(c3C5=O)CCC4=O)cc(=O)oc2c1 +Cc1cccc(COC(=O)N2CCC(CNc3ncccn3)CC2)c1 +O=S(=O)(c1ccc(F)cc1F)n1cc(Cl)c2cc(CN3CCNCC3)ccc21 +O=C1NCC2(CN(CCF)C2)c2[nH]c3c(c21)CCc1cnc(-c2ccccc2F)cc1-3 +N#CCNC(=O)C(Cc1ccccc1)NC(=O)c1ccc(-c2ccccc2)cc1 +O=C(Nc1cc(Cl)ccc1-c1ccccc1)c1cnn2cccnc12 +Cc1ccc(CN2C(=O)C(=O)c3cc(Br)cc(Br)c32)cc1 +NCc1cc(OC2CCCN(C(=O)Nc3ccccc3)C2)nc(C(F)(F)F)c1 +NS(=O)(=O)c1ccc(Cc2c(-c3ccccc3)nn(-c3nc(C(=O)O)cs3)c2C2CC2)cc1 +CN1CCN(NC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +NC(N)=Nc1ncc(Cl)c2ccc(S(N)(=O)=O)cc12 +Cc1cc(C)cc(NC(=O)c2csc(-c3ccc(OC(F)(F)F)cc3)n2)c1 +Nc1nccc(-c2ccc(N)c(C(=O)Nc3cnccc3N3CCCC(N)C3)n2)n1 +CC(O)(C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2)c1cn[nH]c1 +O=C(O)CCn1cc(Cc2cccnc2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc21 +FC(F)COc1ccc(C(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCNCC4)nc12 +COc1ccc(S(=O)(=O)C(CCC(=O)N(C)c2ccccc2)CC(=O)NO)cc1OC1CCCC1 +O=C(NCc1ccc(N2CCCCCC2)cc1Cl)Nc1cccc2[nH]ncc12 +O=C(O)CCn1cc(Cc2ccc(F)cc2)c2cc(NS(=O)(=O)c3ccc(Cl)cc3)ccc21 +O=C1NC(C(=O)O)Cc2cn(cn2)CC=CCOc2ccc(Cl)c1n2 +O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 +NS(=O)(=O)c1ccc(NC(=O)C=Cc2ccc(C(F)(F)F)cc2)cc1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCC(N(C)C)CC3)cc2c1=O 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+COC(=O)c1cc(C(=CCCN=[N+]=[N-])c2cc(Cl)c(OC)c(C(=O)OC)c2)cc(Cl)c1OC +CCNC(=O)C1OC(n2cnc3c(Nc4ccc(OCC(=O)Nc5ccc(F)cc5)cc4)ncnc32)C(O)C1O +CCc1cc(CC)c(OC)c(C(=O)NCC2CCCN2CC)c1O +O=C1NC(=O)C(O)(CC(=O)c2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)C(=O)N1 +C#CCOC(=O)N1CCCN([N+]([O-])=NOc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])CC1 +CCCSc1nc(Oc2cccc(CCC(=O)O)c2)ccc1C(=O)NC1CCCCC1 +CCOP(=O)(OCC)C1(NS(=O)(=O)c2ccccc2)C=C(Cl)C(=O)c2ccccc21 +O=Cc1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccccc2)sc2ccccc12 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(Br)c3c2)c1F +CC1c2nnc(C(F)(F)F)n2CCN1C(=O)CC(N)Cc1cc(F)ccc1F +CC(=O)N1CC=C(c2cncnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1 +CC(Cc1ccccc1)N(CCCc1ccccc1)Cc1ccccc1 +Cc1cc(OCc2cc(-c3ccc(OC(F)(F)F)cc3)cc(-c3ccc(OC(F)(F)F)cc3)c2)ccc1OCC(=O)O +CN(C)C(=O)c1cc(OCCCN2CCCCC2)ccc1OCc1ccccc1Cl +C=CCN1C(c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)=NC(=O)C1(C)C +N#Cc1ncc(F)c(N(CCOc2ccc(Cl)cc2)Cc2ccc3c(c2)OCO3)n1 +O=C1C(c2ccc(O)cc2)=C(c2ccccc2)c2cc(O)ccc21 +O=C(Nc1ccc2c(c1)OCO2)c1ccccc1Cn1ccc2ncnc-2c1 +CC1CCC(C(O)c2ccc(Cl)c(Cl)c2)N1C(=O)Nc1ccc(CNC(=O)C(C)(C)C)cc1 +N#Cc1ccc(S(=O)(=O)C2CCN(CCc3ccc(F)cc3F)CC2)cc1 +COCC1CCCN1C(=O)c1cn2c(-c3ccc(Cl)cc3Cl)c(CN)c(C)nc2n1 +CC1CCCCC1N(C(=O)c1cc(C2CC2)on1)C1CCCCCC1 +CCOc1ccc(C=CC(=O)N2CCN(S(=O)(=O)c3ccc(Br)cc3)CC2)cc1 +O=C(Nc1ccccc1)NC1C2CCN(CC2)C1Cc1cccnc1 +N#Cc1cc2cc(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)c(O)cc2n1Cc1cn[nH]c1 +CC(C)Oc1cc2c(-c3cc(N4CCOC(C)C4)ncn3)n[nH]c2cc1F +O=C1C(=O)N(Cc2cccc(I)c2)c2ccc(S(=O)(=O)N3CCCC3CF)cc21 +FC(F)(F)Oc1cccc(-n2nnc3ccc(N4CCC5(CCNCC5)C4)nc32)c1 +COc1ccccc1N1CCN(CCCCCNC(=O)c2nnn(Cc3ccccc3)c2C)CC1 +COc1ccc2c(c1)C(C)=CC(C)(C)N2S(=O)(=O)c1ccc(NC(C)=O)cc1 +COc1cc(NC(=O)Cc2cccc(C(F)(F)F)c2)ccc1C=NNC(=O)c1ccc(O)c(C#N)c1 +Cc1nc(O)c2cc(CN(C)c3ccc4c(c3)CN(C(CCC(=O)O)C(=O)O)C4=O)ccc2n1 +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCOCC1 +Cc1ccc(NC(=O)CN2C(=O)NC(=Cc3cccn3-c3ccc(C(=O)O)cc3)C2=O)cc1 +COc1ccc(S(=O)(=O)n2c(C)c(C(=O)N3CCCNCC3)c3cc(C)ccc32)c(C)c1C +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=S)Nc1cccnn1)CC2 +NC(=O)c1cccc2[nH]c(-c3ccc(-c4noc(=O)[nH]4)cc3)nc12 +COc1ccc2c(c1)OCCC=CCN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3cccc(Cl)c3)ccc2n1 +Cn1cc(C2=C(c3cn(CCCn4ccnc4)c4ccccc34)C(=O)NC2=O)c2ncccc21 +Cc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCCO2)[nH]1 +COc1cccc2c1-c1ccc(NS(C)(=O)=O)cc1C(c1cc(C)cc(C)c1)O2 +Cc1ccc(-c2cc(NCCCn3ccnc3)c3ccccc3n2)cc1 +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccccc4C(F)(F)F)O2)C3=O)cn1 +Cc1cn2c(n1)CN(C(=O)c1cccc(C(F)(F)F)c1Cl)CC2 +Cc1cc(NC(=O)Nc2cc(C3CC3(F)F)nn2-c2ccccc2)ccc1F +CCOc1ncc2c(n1)c(NC1CC1)nc1cc(C(=O)O)ccc12 +O=C(Nc1n[nH]c2ccc(Cc3cc(F)cc(F)c3)cc12)c1ccc(CN2CCCCC2)cc1NC1CCOCC1 +NCC1CCC2CN(c3cc(N)n4nc(-c5ccco5)nc4n3)CCN2C1 +CC(C)(C)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1 +CCCCCCN(CCCCCC)C(=O)C1CCCc2c1c1ccccc1n2CCF +CCC(C)CCC=C(C)CC(C)CCC=CC(O)C1(C)CCC(=O)O1 +COc1cc(OC)c(F)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3ncccc23)c1F 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+O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2nc(CN3CCN(CCN4CCOCC4)CC3)ccc2c1 +COc1ccc(-c2c(C(=O)NS(C)(=O)=O)n(Cc3cccc(C(F)(F)F)c3)c3ccccc23)cc1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4ccnnc4)s3)c2)C(O)C(O)C1O +Cc1ccc2nc(Cl)c(C=CC(=O)c3ccc(C)s3)cc2c1 +C=CC(=O)NC1=CC=C2N=CN=C(Nc3ccc(OCc4ccccc4)cc3)C21 +COC1CN(c2nc(-c3nccs3)c(C(=O)O)s2)CCC1NC(=O)c1[nH]c(C)c(Cl)c1Cl +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cscn1 +CC#Cc1cc2cc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)ccc2cn1 +COc1c(C)c(O)c(C=O)c2c1C(O)CC(c1ccccc1)O2 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)NC1CCC(Oc2ccc(C(F)(F)F)cn2)CC1 +CCOCc1noc(N)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CCNC(=O)c1cnc(N)c2cc(-c3ccc(N4CCOCC4)cc3)sc12 +N#Cc1cnc(-n2cc(C(=O)Nc3ccc(C4CNCCO4)c(F)c3)cn2)cn1 +NC(=O)c1cccc(-c2ccc3c(c2)nn2cc(-c4ccccc4)c(-c4ccc(C5(N)CCC5)cc4)nc32)c1 +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccccc2)nc2cc(Cl)ccn12 +O=C(c1ccc(OCC(F)(F)F)nc1)N1CCC(O)(c2ccccc2)C2CCCCC21 +CC1NCc2cncn2Cc2ccc(C#N)c(c2)Oc2ccc3cccc(c3c2)NC1=O +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccccc4F)ncc23)ccn1 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+COc1ccc(NC(=O)Nc2nn(-c3ccccc3)c(=O)c3ccccc23)cc1 +O=C(C(c1ccc(Cl)cc1)c1cncnc1)N1CCN(c2ccc(C(F)(F)F)cc2)CC1 +Cc1nc(NC(C)c2cccc(OCc3nc(C(=O)O)co3)c2)cc(-c2ccc3ncsc3c2)n1 +CC1(O)CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)C1 +Cc1cccc(-c2c(-c3cccc(OC(F)(F)F)c3)cc3n2C(CCNC(=N)N)CNC3=O)c1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1Nc1cnn(CC(F)(F)F)c1 +CC(C)CC(NC(=O)C(O)C(N)Cc1ccccc1)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)O +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(Cn2cc(F)cn2)CN1 +O=C(O)c1ccc(COc2ccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)cc2)cc1 +Cn1cc(Nc2ncc(Cl)c(NC3CC4CNCC4C3)n2)cn1 +O=C(O)c1ccc(N2CC3(CCN(Cc4nc(-c5ccccc5)oc4-c4cc(F)c(F)cc4F)CC3)OC2=O)cc1 +Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(c1)OCc1ccc(OCC3COC(C)(C)O3)cc1C2=O +CC(C)(CC(=O)N1CCOCC1)NCC(=O)N1CC(F)CC1C#N +Fc1cc(-c2ccccn2)cn2c(C(F)(F)c3ccc4ncccc4c3)nnc12 +CN1CC(C)(COc2ccc(C(=N)N)cc2)Oc2cc(N(CC(=O)O)Cc3ccc(F)c(F)c3)ccc21 +CC(C)N1CCCN2C(=O)c3c(O)c(=O)c(C(=O)NCc4ccc(F)cc4)cn3CC21 +CCOc1ccccc1-c1ccc(-c2nc3ccc(F)cc3c(NCC(=O)O)c2C#N)cc1 +Cc1cc(-c2cc(C(=O)NC3C4(C)CCC(C4)C3(C)C)nn2-c2ccccc2)ccc1Cl +CC1CCC(Oc2ccc3ccccc3n2)CN1C(=O)c1ccccc1-n1nccn1 +CC1CN(Cc2ccc(Cl)cc2Cl)C(=O)C(=O)N1c1ccccc1 +CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(C(=O)Nc2ccccc2)c(F)c1 +CN(CC(=O)NC(CCCSC(=N)N)B(O)O)C(=O)CCc1ccccc1 +O=C(CCCc1ccccc1)Nc1nc2ccccc2c(=O)s1 +CCCCc1nc(SCSC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 +O=C1NC(=O)C(Cc2ccc(Oc3ccc(F)cc3)cc2)S1 +NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)CCO)c(F)c1F +CC(C)(C)c1ccc(-c2cccc(NC(=O)Nc3ccc(Cl)cc3)c2)cc1 +OC(O)(CCCCCNc1c2c(nc3ccccc13)CCCCC2)C(F)(F)F +CC(C)CC(NC(=O)C1(c2ccccc2)CC1CN1CCC2(C)c3cc(O)ccc3CC1C2C)C(=O)NCCCCN +CC(=O)Nc1nc(C(CCN2CCC(c3ccccc3)CC2)C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cs1 +c1ccc2c(CCN3CCCC(c4ccnc(NC5CC5)n4)C3)csc2c1 +CCNC(=O)c1ccc(-n2cnc3cc(Cl)ccc32)s1 +CC(=O)c1cn(C)c2ccc(Nc3nccc(-n4cc(CN5CC(O)CO5)c(C)n4)n3)cc12 +CCC(=O)CCC(=O)NC(Cc1ccccc1)C(O)CN(CC(C)CC)S(=O)(=O)c1ccc(OC)cc1 +O=C(NCC(c1cnc(C(F)(F)F)nc1)N1CCOCC1)c1ccc(Cl)cc1Cl +COc1ccc(C2=C(c3ccc(F)cc3)C(=O)OC2)cc1 +O=C1NC(=Nc2nc3ccccc3s2)SC1=Cc1ccccc1Cl +CCCn1c(=O)[nH]c2nc(-c3cnn(CC#Cc4cccc(C(F)(F)F)c4)c3)[nH]c2c1=O +Clc1ccc(N2CCN(CCCCc3nc4ccccc4o3)CC2)cc1 +COc1cc2[nH]c(=O)n(C)c(=O)c2cc1-c1cnco1 +COc1c(C)cc(S(=O)(=O)N2CCCC(Cn3ccnc3)C2)cc1C +O=S(=O)(Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1)c1ccc(I)cc1 +O=C(O)c1ccc(S(=O)(=O)N(CCCC(F)(F)F)c2sc3ccccc3c2Cl)cc1 +c1c2c(cc3c1SSc1cc4c(cc1SS3)OCCO4)OCCO2 +CC(C)n1cc(C2=NCC(=O)N3CCc4c(cccc4-n4cccn4)C3=C2)cn1 +Cn1cccc1-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1 +COc1ccc(CCc2cnc3nc(N)nc(N)c3c2)cc1OC +Cc1cc(C)c(S(=O)(=O)N2CCC(C(=O)NC3CCCC3)CC2)c(C)c1 +COc1ccccc1-c1cccn2nc(Nc3cccc(N4CCN(C)CC4)c3)nc12 +Cc1ccc(C(C)(C)NC(=O)COc2cc(C)c3c(C4CC4)nn(C)c3n2)cc1 +Cc1cc(C(Nc2ccc(Cl)c(CNCCC(=O)O)c2)C(F)(F)F)ccc1Cl +Cc1ncccc1C(C#N)N1CCN(C(=O)CC(NCc2ccccc2)c2ccccc2)CC1 +Oc1nc(NCCCNC2CCNc3c(Br)cc(Br)cc32)nc2ccsc12 +CN(C)CCNC(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C +COc1ccc(Br)c(CC2CCN(CCc3ccc4ccccc4c3)CC2)c1 +OCc1ccc(C#Cc2cncnc2Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)o1 +Cc1cc(CCN2CCOCC2)ccc1Nc1nccc(-c2c[nH]c3ncccc23)n1 +CC(C)c1nc(C(=O)NC2CCN(CCF)CC2)c2ccccn12 +Clc1ccc(Cl)c(-c2cc(Cl)cc3c2N2CCNCCC2C3)c1 +O=C(Nc1ccccc1)c1cccc(-c2cnc(-c3c[nH]c4ccccc34)[nH]2)c1 +c1ccc(C2=NN(c3ccccc3)C(c3ccc4ccccc4c3)C2)cc1 +CC1OC(=O)C2(NCc3cscn3)CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4C#N)cn3)C12 +CC1=CC(C)(C)N(Cc2ccccc2)c2ccc(OC(=O)C3CCCCC3)cc21 +O=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1nc2ccccc2[nH]1 +O=S(=O)(Nc1cccc2cccnc12)c1ccc(Cl)cc1F +O=C1CC(O)CC(CSc2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)O1 +O=C(c1ccco1)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1cnccc1-c1ccccc1 +C#Cc1ccc2c(c1)N(CCCN(C)C)c1ccccc1CC2 +CC(=O)CCCCC(=O)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1C(=O)NCc1cccnc1 +COc1ccc(O)c(CNc2ccc(S(N)(=O)=O)cc2)c1 +Oc1c(-c2ccncc2)c(-c2ccc(F)cc2)nn1-c1ccc(Cl)cc1 +O=C(O)CCc1c(C(=O)O)[nH]c2cc(Cl)ccc12 +O=C(NCCC1CN=C(c2ccccc2)c2ccccc2N1)c1ccc(F)cc1 +Fc1cccc2c1[nH]c1c3c4ccccc4nc-3c[nH]c12 +O=C(O)COc1cccc2c1CCC(COC(=O)N(c1ccccc1)c1ccccc1)C2O +C=C(C)C1CCC2(NC(=O)NC(C)(C)CO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +COc1cc(C=CC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OC +CC(NS(=O)(=O)C(C)C)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1 +Cc1ccc(-c2ccn[nH]c2=O)cc1NC(=O)C1=CN(C)C(=O)CC1c1ccc(F)cc1 +Cc1c(C(O)CN2CCC3(CCCN(C(=O)c4ccc(-n5cnnn5)nc4)C3)C2)ccc2c1COC2=O +CCNC(=O)c1ccc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4ccc(OC)cc4F)cc32)cc1C +O=C1SC(=Cc2cccc(OCc3ccc(B(O)O)cc3)c2)C(=O)N1Cc1ccc(F)cc1 +COC1CCC(Nc2cc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 +CCn1c(CNc2ccc(Cl)cc2)nnc1SCC(=O)Nc1cccc(C)c1C +O=C(Nc1nc(-c2ccccc2)nc2nn(CCc3ccccc3)cc12)c1cccc(Cl)c1 +COc1ccccc1N1CCN(CCCn2nc(-n3cnc4ccccc43)ccc2=O)CC1 +CCC1OCC(=O)C1NC(=O)C(CC1(C)CCCC1)NC(=O)c1ccc(NS(=O)(=O)c2cccc(F)c2)cc1 +Cc1cccc(C)c1N1CC(C(=O)Nc2cc(N3CCCC3)cc(C(F)(F)F)c2)CC1=O +Cc1nn(-c2cccc(N)c2)c2oc3ccccc3c(=O)c12 +CCCCn1nc(C(C)C)c(C(=O)O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 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+CCN(C)S(=O)(=O)Nc1cc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(Cl)cc4)cc23)c(F)c1 +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(C)c3)n3c2CCOC(C)C3)cc(CO)n1 +O=C(O)Cc1cccc(CNc2cccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1 +O=C(O)c1ccc(CN2C3CCC2CC(Nc2ccc(Oc4ccc(-c5ccccc5)cc4)cc2)C3)cc1 +Cc1cc2n[nH]c(=O)n2c2cc(-c3ccc(C#N)cc3)ccc12 +O=C(Nc1cc(-c2ccccc2)ccc1O)c1nc2ccccc2s1 +CCN(CC)c1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(C(F)(F)F)c1Oc1ccccc1 +O=C(C=Cc1cccc2c1N(Cc1ccc3ccccc3c1)C(=O)C21OCCO1)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +NS(=O)(=O)c1cc(C(=O)NC(Cc2c[nH]cn2)C(=O)NCC(=O)O)ccc1Cl +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5ccoc5)cc4F)nccc3c2Cl)CS1(=O)=O +Cn1cc(-c2c[nH]c3ncnc(N4CCOCC4)c23)cn1 +CNc1ccc2cc(NC(=O)CCc3ccc(C(F)(F)F)cc3)ccc2n1 +Cc1ccc(Oc2cnc(CN3CCC(O)=C(C(=O)NCC(=O)O)C3=O)cn2)cc1 +COc1cc2nc(N3CCN(c4ccnc(N5CCOCC5)n4)CC3)nc(N)c2cc1OC +CCCCN(CC)c1cc(C)nc2c1NCCN2c1ccc(C#N)cc1C +O=C(CCCN1CCN(c2cccc(Cl)c2)CC1)NCc1nc2ccccc2c(=O)n1-c1ccccc1 +Fc1ccncc1-c1ccc2[nH]nc(-c3cncc(OC4CNCCC45CC5)n3)c2c1 +Cc1c(Cl)cccc1-c1ccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)o1 +CN1C(=O)NCC1C(=O)NCc1c(F)cc(Cl)cc1Cl +CC(C=CCC1(c2cc(C(C)(C)C)cc(C(C)(C)C)c2)CC1)=CC(=O)O +O=C(Nc1ccc(C(F)(F)F)cc1)c1cc[nH]n1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)C3(C)CCC3)cs2)CO1 +CC(NC1CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1)C(O)c1ccccc1 +COc1cccc(OC)c1C1CCCCC(=O)N1Cc1ccc2ccccc2n1 +NC(=O)c1ccc(-c2ccc(-c3cc(NCc4cccnc4)n4ncc(Br)c4n3)cc2)c(O)c1 +COC(=O)C(C)(C)c1ccc(Nc2nc(C(C)C)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CC(C)c1ccc(N2CCc3cc(O)ccc3C2(C)c2ccc(C=CC(=O)O)cc2)c(F)c1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc([N+](=O)[O-])cc4)cc3)[nH]c2n(CCC)c1=O +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(NCCN1CCCCC1)c1ccsc1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C5CCCC5)on4)c3)c2cc1OC +CS(=O)(=O)CCNC(=O)C1=Cc2c(ncnc2Nc2ccc(Oc3cccc4sccc34)c(Cl)c2)NCC1 +FC(F)(F)c1ccc(Nc2nc(OC3CCCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CC=CC1CC(C(=O)O)NC1C(NC(C)=O)C(C)(CCC)OC +CN(c1cccc(N)c1)c1ccc2c(C=Cc3ccc4c(c3)OCO4)n[nH]c2c1 +CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]c(=NC(=O)c1ccc(C=Cc3ccncc3)s1)n2CCC(N)=O +NCCCCC(NC(=O)C(F)(F)F)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 +CN(C)C(=O)Cn1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21 +CC1c2cc(O)ccc2OC(c2ccc(OCC(C)N3CCCC3)cc2)C1c1ccc(O)cc1 +COc1cc2c(cc1OC)C1=NOC(CN3CCN(Cc4ccc5ccccc5c4)CC3)C1CN2 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCCC(N)CC1 +O=c1c2c(oc(O)c1C(c1cccc(NS(=O)(=O)c3ccccc3)c1)C1CC1)CCCCCC2 +O=C(Oc1cncc(Cl)c1)c1ccc(-c2ccc([N+](=O)[O-])cc2)o1 +CN=C(C(C=N)NC(=O)c1nc(-c2c(F)cccc2F)sc1N)N1CCC(N)CC(F)(F)C1 +C=C(F)CN(CCOC)C(=O)C1(c2ccsc2)CC1CN +CC(C)(C)C1CCC(c2cc(C(=O)NN)nc3ccccc23)CC1 +CC(C)Cc1cc(-c2ccc(CCNC(C)C(O)c3ccccc3)cc2)ccc1C(=O)O +Cc1cc(C(Cc2ccccc2)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)ccc1OC(F)F +O=C(NC(=O)c1ccc(F)cc1Cl)Nc1ccc(C(=O)O)c(O)c1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1SC1CCCCC1C)c1ccc(NS(C)(=O)=O)c(F)c1 +CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)C3(c4ccccc4)CCCC3)cc2F)CC1 +CCOC(=O)NCc1cc(C(C)C(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F 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+CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N2CCCC2CO)cc1-c1ccccc1Cl +COc1cccc(-c2cn3cc(OCCCN4CCCCC4)cc3c(=O)n2CC(=O)NC2CC2)c1 +Cc1ccc(NC(=O)N2CC(CC#N)(n3cc(C(N)=O)c(Nc4ccccc4)n3)C2)cc1F +CCCCc1nc(CCC)c(CCC(=O)OCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 +O=C(NC1CCCCN(Cc2c(F)cccc2F)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +O=C(Nc1cc(Cl)cc(Cl)c1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1 +CC(C)N1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cn(C)cn5)n4)cc(Cl)c3[nH]2)CC1 +Nc1nc2[nH]c(SCc3ccc(Br)cc3)nc2c(=O)[nH]1 +COc1cc2c(c(OC)c1)C1C3CCCC(C(=O)N1CC2)N3C(=O)C(=O)c1ccc(Cl)cc1 +O=C(O)CCC1(O)OC2=CC(=O)c3c(O)cc(O)cc3C2=C1c1ccc(O)cc1 +CN(CC12CCC3(O1)C1Cc4ccc(O)cc4C3(CCN1CC1CC1)C2)C(=O)c1ccccc1 +CCCCN(CCCC)C(=O)C1OC(C(=O)O)=CC(N=C(N)N)C1NC(C)=O +CC(=O)N1CCCC1C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 +CCCCCCCCc1nc(-c2cc(S(=O)(=O)N3CCN(C)CC3)ccc2OCC)[nH]c(=O)c1Br +Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CNC(C)C)c3)cc2)c(CC(C)C)nn1C +NS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CC3(CCC3)C2)cc1 +Cc1ccc(-c2cc(C(=O)NCc3ncc[nH]3)nc(N)n2)o1 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+COc1cc2c3c(c4ccc(OC(C)=O)cc4c2cc1OC)CC1CCCN1C3 +O=C1NCCn2c(-c3cccc(Cn4cccc4)c3)cc3cccc1c32 +COc1ccc(N(C)c2nc(N=[N+]=[N-])nc3ccccc23)cc1 +FC(F)(F)c1cc(Cl)c(-n2cc(C3(C(F)(F)F)N=N3)cn2)c(Cl)c1 +FC(F)(F)c1cc(COCC(c2ccccc2)N2CCN(Cc3nn[nH]n3)CC2)cc(C(F)(F)F)c1 +COc1cc[nH]c1C=C1C(=O)Nc2ccc([N+](=O)[O-])c(NC3CCC(O)C3)c21 +COCCC(=O)N1CC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +Cc1ccnc(-n2[nH]cc(-n3ccnn3)c2=O)c1 +Cc1cc(NC(=O)Nc2cc(C3CC3C)nn2Cc2ccccc2)ccc1F +Cc1cc(-c2c(C(N)=O)c3cc(F)c(OC(F)F)cc3n2-c2ccccc2)ccc1NS(=O)(=O)C(C)(C)C +Cc1oc(-c2ccccc2)nc1CCOc1ccc(OC(C)(C)C(=O)O)cc1 +CCN(C)C(C)(C)c1nc(O)c(O)c(C(=O)NCc2ccc(F)cc2)n1 +COc1ccccc1CNC1CCCNC1C(c1ccccc1)c1ccccc1 +CCN(CC)CCOc1ccc(CCc2ccc(-c3ccc(OC)cc3)cn2)cc1 +C#CCNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(NCCC)c3F)C2)cc1 +CN(C)c1ccc(C#Cc2ncnc(NCCc3c[nH]cn3)c2-c2ccc(Cl)cc2)cc1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)cc1)c1nnn(-c2ccc(F)cc2)c1C(F)(F)F +Cc1ncnc(C)c1-c1ccc(Oc2nccc3[nH]ccc23)cc1C#N +CCc1cccc(CC)c1NC(=O)c1cc(-c2ccnc(Nc3ccc(N4CCN(CCO)CC4)cc3OC)n2)n(C)n1 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+CCCCc1c[n+](Cc2ccc(-c3ccccc3C(=O)O)cc2)cn1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cc1cnc(Cl)nc1-c1ccc(N(Cc2ccc(CNC(=O)c3ccccc3)cc2)C(=O)c2ccc(O)cc2O)cc1 +COc1cc2ncnc(Nc3ccc(C(=O)NC45CC6CC(CC(C6)C4)C5)c(Cl)c3)c2cc1OCCCN1CCOCC1 +Cc1nc2sc(C(=O)NC3CCCCC3)c(N)c2c(C)c1Cl +O=C(OCCCc1ccc(F)cc1)C1CCCCN1S(=O)(=O)c1ccccc1 +O=C(O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc(-c2cnn(Cc3ccccc3)c2)c1 +CN(C)CCNc1ccc2c3c(cccc13)C(=O)N(CCN(C)C)C2=O +COc1ccc(Cl)cc1N1CCN(CCCn2nc(-c3ccccc3)c3c(C)onc3c2=O)CC1 +COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccc(-c3cnn(CC(C)C)c3)cc1)CC2 +CC1(c2sc(C#CC3CCCC3)cc2Cl)CS(=O)(=O)C2(CCC2)C(=N)N1 +CC1(C)Oc2ccc(-c3nc(-c4cccc5c(CCC(=O)O)c[nH]c45)no3)cc2O1 +O=S(=O)(c1ccc(F)cc1)N1CCCC2CN3CCc4ccccc4C3CC21 +CCN(CCc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +Cc1ccc(C2CC2COc2nc(C)ncc2-c2cc(=O)[nH]cc2C)nc1 +COc1cc(C2C(C#N)=C(N)Oc3c2ccc(N)c3N)cc(I)c1OC +CCCCCNc1nc2nn(C)cc2c2nc(-c3ccco3)nn12 +CCC1(c2cccc(Oc3cc(C(N)c4cncn4C)ccc3C#N)c2)CCCCN(C)C1=O +CCCn1c(=O)c2[nH]c(-c3cc(C)n(CC(=O)Nc4ccc(C)cc4)n3)nc2n(CCC)c1=O +CCCCOC(=O)NC(CCC(=O)N1CCC2(CC1)CCN(c1ccncc1)CC2)C(=O)O +Cc1cc(N2C(=O)c3c(c(C(F)(F)F)nn3C3CC3)C2c2ccc(Cl)cc2)cn(C)c1=O +COC(=O)c1ccc(CSc2ncnc3c2oc2ccccc23)o1 +COc1cc(Nc2ncc3ccn(-c4cccc(C(=O)NCCO)c4)c3n2)cc(OC)c1OC +O=C(OC1CCN(c2ccncc2)CC1)N1CCN(C2CCC2)CC1 +COc1cc(Cl)c(Nc2nc(C#N)cn(C(COCCF)C3CC3)c2=O)c(Cl)c1 +N#Cc1cnc2ccc(-c3cccc(CN4CCOCC4)c3)cc2c1NC1CC1c1ccccc1 +Clc1ccc2c(c1)CCc1cccnc1C2=C1CCN(Cc2ccncc2)CC1 +Cc1ccc(-c2nc3c(CNC4CC4)c(O)ccc3[nH]2)cc1 +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)N4CCN(C(C)C)CC4)c4ccc(C)cc34)cc2)c1C +Cc1ncc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NC1CCCN(C(=N)N)C1O +O=C(O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2F)n1 +COC(=O)c1cc2cc(NCc3cc(NC(=O)c4ccc5[nH]ccc5c4)ccc3C)cnc2[nH]1 +Cc1noc(C)c1-c1ccc2ncn(Cc3cccc(C(=O)N(C)C)c3)c2c1 +CN(CC(c1ccccc1Br)N1CCC(N2CCCCC2)CC1)C(=O)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COCCN(C)c1ncc2ncnc(Nc3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3OC)c2n1 +COc1ccc(-c2ccc(NC(=O)Nc3cccc(Br)c3)cc2)c2c(N)noc12 +CC(CCc1ccc(-c2ccc3nonc3c2)cc1)(C(=O)NO)S(C)(=O)=O +CCOc1nn(-c2cccc(Oc3ccccc3)c2)c(=O)o1 +Nc1nccn2c(C3CCC3)nc(-c3ccc4cccnc4c3)c12 +Cc1nc2ccc(CN3CCOCC3)cc2n2c(-c3cc(OC(C)C)ccc3Cl)nnc12 +COc1ccc2c(c1)CCN=C2c1ccc(S(N)(=O)=O)cc1 +COc1ccc(Cl)cc1CC1CNC(=NOc2ccc(F)cc2)CN(C(=O)NC(C)c2ccc(CC(=O)O)cc2)C1=O +CCc1nn2cc(-c3nc4ccc(OCc5cccc(Cl)c5)cc4o3)nc2s1 +CNS(=O)(=O)c1cccc(Nc2cc(Nc3ccc(C(F)(F)F)cc3)ncn2)c1 +O=C(O)C(CC1CCC1)N1CC(CN2CCC(c3cnc4ccc(Cl)cn34)CC2)C(c2cccc(F)c2)C1 +COc1ccc(S(=O)(=O)N2CCOc3ccc(F)cc32)cc1NC1CCN(C)CC1 +CN(C)CCCCNC(=O)c1cccc2c(N)c3ccccc3nc12 +N#Cc1c(F)c(F)c(NC(=O)c2cc3ccccc3oc2=O)c(F)c1F +CCN(CC)CC[S+]([O-])c1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +COc1cccc(N2CCN(c3nc(NC4CCCNC4)c(-c4nc5ccccc5s4)c(=O)[nH]3)CC2)n1 +O=C(O)c1cc(OP(=O)(O)O)cc(OP(=O)(O)O)c1 +CC12CCC3C(CC(=O)C4CC(=NOCCCN)CCC43C)C1CCC2=O +CCc1ncnc(N2CCC(O)(CC)CC2)c1C#Cc1ccc(C)nc1 +CN(C)CCNC(=O)c1ccc2nnc3c(c2c1)C(=O)c1ccccc1-3 +COC(=O)NC1CCC(Nc2cc(NC(C)c3ccc(Cl)cc3)ncn2)CC1 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+O=C(Nc1ccc(F)cn1)C(CN1CC(O)C1)Oc1ncnc2c1cnn2-c1c(Cl)cccc1Cl +CC(=O)OC(C(CC1CCNC1=O)NC(=O)C(CC1CCCCC1)NC(=O)OCc1ccccc1)S(=O)(=O)O +CN(C)CCSc1cc(-c2cn[nH]c2)ccc1NC(=O)NCc1ccccc1 +Cc1onc(-c2ccccc2)c1C(=O)N1CCN(C(=O)N2C(=O)C(CC3CCNCC3)C2C(=O)O)CC1 +[C-]#[N+]c1cnc2c(Nc3nc(C)n(C)n3)nc(Nc3ccc4c(c3)c(C#N)nn4C)nn12 +NCc1ccc(NC(=O)CC2CCc3cc(Cl)cc4[nH]c(C(=O)O)c2c34)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1Nc1cc(C2CC2)n[nH]1 +CC(NC(=O)c1ccc(CC2CCN(Cc3ccc4c(c3)OCO4)CC2)cc1)c1ccc(Cl)cc1 +CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(CCN5CCN(C)CC5)c4)cc2)CC3)n1 +CN1C(=O)C=CC2(C)C3CCC4(C)C(O)C(=Cc5cc(F)cc(F)c5)CC4C3CCC12 +O=C(Nc1nc2ccc3[nH]ncc3c2s1)C1CCCN1c1ccc(Cl)cc1 +COc1ccccc1-c1cc(C2=Nc3c(C(C)(C)C)nn(CCCO)c3C(=O)NC2)ccc1OC +CC1(C)CN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CCN1 +CCc1cc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC(C)N(CC4CCOCC4)CC2C)C3(C)C)on1 +COc1ccc(CN(C)CCCSc2ccc(NC(=O)c3cccc4c(O)c5ccccc5nc34)cc2)cc1OC +c1ccc(CN2CCC(NCCOC(c3ccccc3)c3ccccc3)CC2)cc1 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+CCOc1nc(C)nn1-c1cc(C2CC2c2nc3ccccc3n2C)nc(C)n1 +CCCCN(CC)c1cc(C)nc2c(-c3ccc(Cl)cc3)c(C)nn12 +O=C(NCc1ccc(S(=O)(=O)N2CCCCC2)cc1)c1cc2cnccc2[nH]1 +COc1ccccc1N(C(=O)OCC1CCC(COCC(=O)O)CC1)c1ccccc1 +CCc1nc2cc(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc(-c2cccc(C(=N)N)c2)cc1 +N#Cc1ccc(Cn2cncc2COCc2ccc(C#N)cc2-c2ccc(Cl)c(Cl)c2)cc1 +O=C1OCCc2cc(C3CN4CCN(C(=O)C5CCc6nc(-n7cnnn7)ccc65)CC4CO3)ccc21 +Nc1nc2c(cnn2CCCc2ccc(OCCF)cc2)c2nc(-c3ccco3)nn12 +O=C(NCCCCO)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +O=C(NCc1ncccn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +O=C(NCC(=O)N(CCO)C1CCOCC1)c1cc2cc(Cl)ccc2[nH]1 +CC(C)n1cc(-c2cc3c(-c4cccc(N5CCNCC5)n4)n[nH]c3cn2)cn1 +CCC(C)N1CC=Cc2c(nc(-c3ccccc3)c3ccccc23)C1=O +CCCCCc1ccc(S(=O)(=O)NCCc2c(-c3cc(OC)ccc3OC)[nH]c3ccccc23)cc1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC2CCN(C(N)=O)CC2)c2ccccc12 +O=C(O)c1ccc2c(c1)nc(-c1ccc(Cl)s1)c1ccncc12 +CC(C)(C)c1ccc(NC(=O)Nc2cccnc2Oc2cccc(C(F)(F)F)c2)cc1 +CCCNC(=O)CCC(NS(=O)(=O)c1ccc(-c2ccccc2)cc1)C(=O)O +CCN(CC)CC1C(=O)OC2CC3(C)CCCC(C)C3=CC21 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+O=C(O)c1ccc(CNC(=O)C2NC3(CCCCC3)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)cc1 +Cc1cc(S(N)(=O)=O)c(S(=O)(=O)C(C)C(=O)O)cc1Cl +CN(C)CCCOc1cc(-c2ccccc2)n(-c2ccccc2)n1 +N#CC1(c2cccc(C(F)(F)F)c2)CCC(CNc2ncccc2NC(=O)CC(F)(F)F)CC1 +O=C(NO)c1cnc(N2CC3C(C2)C3NCc2ccc(OC(F)(F)F)cc2)nc1 +Cc1cc(-c2nnn(CC3CCC(CO)CC3)n2)cc(C(=O)NCc2cccc(Cl)c2)n1 +COC(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(-n2cccc2CN2CCNCC2)cc1)c1ccccc1 +COc1ccc2[nH]c(C(=O)c3ccc(OC)c(OC)c3)cc2c1 +COc1cc(OC)cc(N(CCCO)c2ccc3ncc(-c4cnn(C5CCCCO5)c4)nc3c2)c1 +O=C(NC1(CO)CCCCC1)c1cnc(C2CC2)c(OCC2CC2)n1 +O=C1NC(=O)c2c1c1c3ccc(O)cc3[nH]c1c1c2c2ccc(O)cc2n1C1OC(CO)C(O)C(O)C1O +CCCN(CCO)CCCOc1cc2ncnc(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)c2cc1OC +O=C(Nc1ccc(-n2cc(-c3ccncc3)c(-c3ccc(Cl)c(O)c3)n2)cc1)c1ccc(Cl)c(C(F)(F)F)c1 +Cc1cc(COc2ccc(C(=O)NC3(CC(=O)NO)CCN(C(=O)CC(C)(C)C)CC3)cc2)c2ccccc2n1 +COc1ccc(N)cc1CN1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1 +CN(C)CCOc1ccc(C(=O)N2CC(=Cc3ccccc3)C(=O)C(=Cc3ccccc3)C2)cc1 +O=C(NCCCCCS(=O)(=O)N(OCCN1CCOCC1)C1CCCCC1)Nc1ccncc1 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+O=C(CC1CCC(c2ccc(-c3ccc4c(c3)OCCN4C(=O)Nc3ccccc3)cc2)CC1)NO +CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(-c2ccc(Cl)cc2)n1 +COc1ccc(CCNC(=O)CC(N)C(=O)N2CCCC2C#N)cc1OC +COC(=O)N1CCC(n2ncc3c(N4C5CCC4COC5)nc(-c4ccc(NC(=O)Nc5cccnc5)cc4)nc32)CC1 +O=S(=O)(c1ccccc1Cl)N(Cc1ccccc1)C1CNCC1N(Cc1ccccc1)S(=O)(=O)c1ccccc1Cl +COC(=O)Nc1cc(C(=O)c2c(C)cncc2C)cc(-c2cccc3[nH]ccc23)c1 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1cn(CCNc2ncnc3ccsc23)nn1 +CS(=O)(=O)c1ccc(C(CCNC(=O)c2ccc(C#N)cc2)c2ccc(F)cc2)cc1 +CC(=O)c1cccc(NC(=O)NCCCN2CC3CCC2C(Cc2ccc(F)cc2)C3)c1 +C=CC(=O)NCc1coc(-c2c(N)ncnc2Nc2ccc(Oc3ccc(Cl)cc3Cl)c(Cl)c2)n1 +COc1ccc2c(c1OCc1ccccc1)CC(C(=O)O)N(C(=O)N(c1ccccc1)c1ccccc1)C2 +CCc1ncnc(-c2ccc(C(=O)NCC3CCCN3CC)c(F)c2)c1C#Cc1ccc(N)nc1 +COc1ccccc1CNCc1cccc(CCNCC(O)c2ccc(O)c3[nH]c(=O)sc23)c1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(F)c(F)c4)cn3CCN3CCCC3)CC2)c1Br +O=S(=O)(O)c1ccc(CCCNc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)C3CCCC3)cc2F)cn1 +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2ccccc2)cc1 +CC1(C)OC(O)=C2C1=NC1=C(C(=O)COC1)C2c1ccc(F)c(Br)c1 +CC(=O)Nc1cc(-c2nc3ccccc3o2)cc(-c2cccc3[nH]ccc23)c1 +O=S(=O)(c1cccc2ncccc12)N1CCC(CCN2CCN(c3ccc(Cl)cc3)CC2)CC1 +CC1=C(c2nc3ccccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)c3ccccc3)CC2)cc1 +CCN(CC)c1ncc(-c2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)cn1 +O=C(O)c1ccc(C(=O)C(=Cc2ccc(Cl)c([N+](=O)[O-])c2)SCc2ccc(F)cc2)cc1 +O=C(CSc1nnc(-c2cccnc2)n1Cc1ccco1)c1ccc2ccccc2c1 +COCCn1c(=O)nc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O +Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2F)c(O)c1CC(=O)NCc1ccc(C(=N)N)cc1 +O=S(=O)(NC1CCC(CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1)c1cccnc1 +CC(C)N(C(=O)C1CCC2C3CCC4N(C)C(=O)C=CC4(C)C3CCC12C)C(C)C +CCNCc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +FC(F)(F)c1ccc(N2CCC(NC(c3ccc(Cl)cc3)c3cccnc3)CC2)cc1 +CCCCCCS(=O)(=O)c1nsnc1C1=CCCN(C)C1 +CCCCCCCCCCCCCC(=O)NC(CCCNC(=N)N)C(=O)Nc1ccn(C2OC(CO)C(O)C2O)c(=O)n1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(NC4CCCC4)c3F)C2)cc1 +COc1c(-n2cnc(C)c2)ccc(-c2cn(C3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)c1F +COc1ccc(-c2c(O)nc3cc(Cl)c([N+](=O)[O-])cc3c2OCCC2CCCCN2)cc1C +Fc1ccc(C(OCCNCCNCCCc2ccccc2)c2ccc(F)cc2)cc1 +COc1cc(-c2ccc3ncnc(Nc4cc(O)c(C)cc4F)c3c2)ccc1O +CC1(C)CCCN(C2(C(=O)N3CC(S(=O)(=O)c4ccccc4Cl)CC3C(=O)NC3(C#N)CC3)CC2)C1 +Cn1c2c(c3cc(S(=O)(=O)c4cnc5[nH]ccc5c4)ccc31)C1CCC(C2)N1 +N=C(N)c1ccc2scc(C(Cc3ccccc3)C(=O)Nc3ccc(-n4cnc5ccccc54)cc3)c2c1 +CN1CCc2c3c(cc4c2C1Cc1ccc(O)c(O)c1-4)SCCC3=O +CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCc1ccccn1 +Nc1c2c(nc3c1C(c1cccc(Cl)c1)c1c(c4ccccc4oc1=O)O3)CCCC2 +CC12CCC(O)CC1CCC1C2CC(O)C2(C)C(c3ccc(=O)oc3)CCC12O +CCN(C(=O)c1cccc(Cl)c1)c1ccnc(NC(C)c2ccccc2)n1 +O=C(Nc1ccc(C(F)(F)F)cc1)N1CC=C(c2ncc(C(F)(F)CO)cc2Cl)CC1 +O=C(O)C1(O)C=C(c2cn(-c3ccccc3)nn2)C(O)C(O)C1 +COc1cc(C(=O)c2csc(-c3cccs3)n2)cc(OC)c1OC +O=C(NCc1ccccc1)C(=O)C(CC1CCNCC1)NC(=O)C1CCCN1C(=O)C1NCCC2CCCCC21 +CCCCCCNC(=O)OCC1NC(=N)CCCC(O)(O)C2NC(=N)NC12 +OC1(c2ccc3ccccc3c2)c2c(c3ccccc3c3ccccc23)C2=NCCN21 +O=C(COc1ccccc1)N1CCCCC1c1csc(-c2ccc(C(F)(F)F)nc2)n1 +COc1ccc(C(=O)O)cc1-c1cccc(COc2ccc3c(c2)CN(C2CCCC2)C3=O)c1 +Cc1cc(COc2ccc(C3CC4(CC4C(=O)NO)C(=O)N3)cc2)c2ccccc2n1 +CS(=O)(=O)c1ccc(OCC2CCCCC2)c(C(=O)N2CCN(c3ccc(C#N)cc3F)CC2)c1 +CNc1nc2cc3c(cc2s1)CC1C2CCCCC32CCN1CC1CCC1 +CC(C)(C)OC(=O)N1CCC(N(C(=O)c2ccc(-c3ccno3)cc2)C2CC2)CC1 +COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCSCC5)cc4)sc23)c(Cl)cc1Cl +CC(CC(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3CCC12C)C(C)(C)O +O=C1C(=O)c2cccc([N+](=O)[O-])c2-c2ccccc21 +CC(C)c1ccc2c(CCCCCCCNS(=O)(=O)c3ccccc3)cc(C(=O)O)c-2cc1 +FC(F)(F)c1ccc(NCCNc2ncc(-c3ncc[nH]3)c(-c3ccc(Cl)cc3Cl)n2)nc1 +CCn1c(=O)cc(C(F)(F)F)c2cc3c(cc21)NC(C)(C)C=C3C +NC(C(=O)N1CCC2CC21)C12CC3CC(CC(O)(C3)C1)C2 +COc1ccc2c(c1)CCN1Cc3c(ccc4[nH]c(C)c(C(=O)OCc5ccccc5)c34)OC21 +COc1ccc(Cl)cc1S(=O)(=O)N1CCSc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 +CN1C(=O)C(=Cc2c[nH]nc2-c2ccccc2)SC1=S +Cc1cc(C(=O)Nc2ccc(-n3ccnc3C)cc2)n(-c2ccc3cc(Cl)ccc3c2)n1 +O=C(O)c1cc2cc(O)c(O)cc2c(C(O)c2ccccc2Cl)n1 +CONC(=O)N(Cc1ccsc1)C1CCN(C(C)CCNC(=O)c2c(C)cc(C#N)nc2Cl)CC1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(-c3ccccc3F)nc21 +CC(Nc1nc2cc[nH]c(=O)c2cc1-c1ccccn1)C(C)(C)C +O=C(NC1CCN(C(=O)CCCCc2c[nH]nn2)CC1)OCc1cc(Cl)cc(Cl)c1 +NC(CCP(=O)(O)C(O)c1ccc([N+](=O)[O-])o1)C(=O)O +O=C1C(NCCN2CCOCC2)=C(Cl)C(=O)c2ncccc21 +Cn1c(=O)c2c(nc(NCCCN3CCN(C(c4ccccc4)c4ccccc4)CC3)n2C)n(C)c1=O +O=C(Nc1ccc(-c2cccnc2)cc1)Nc1ccc(Cl)c(Cl)c1 +Cc1ccccc1C(=O)c1ccc(Nc2ccccc2N)cc1 +N#Cc1cccc2c(OC3CCC(NC(=O)c4ccc(Cl)c(F)c4)CC3)ccnc12 +COc1cccc(-c2cc3c(nn2)-c2ccccc2C3=O)c1 +O=C1C(Oc2ccc(Cl)c(Cl)c2)CC=CCN1C(CN1CCCC1)c1ccccc1 +N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)cc2F)n2ccnc2)cc1 +CC(C)(Cc1ccc(Oc2ccc(C(N)=O)cn2)cc1)NCC(O)COc1cccc2c1C1(CCCCC1)C(=O)N2 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-c3cccs3)ccc(F)c12 +O=C(CN(Cc1ccc([N+](=O)[O-])cc1)Sc1ccccc1[N+](=O)[O-])NO +Cc1c(C2(N3CCCCC3)CCC(c3ccccc3)(N(C)C)CC2)[nH]c2ccccc12 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2nc(-c3cccnc3)cs2)cc1 +COCc1c(-c2ccc(C(=N)N)cc2)oc(-c2ccc(C(=N)N)cc2)c1Cl +O=S(=O)(c1ccccc1)n1ccc2c3c(ccc21)C1CCNCCC31 +Cc1cc(C)c(NC(=O)c2ccc3nc(Nc4ccccn4)sc3c2)c(C)c1 +CCN(C(=O)C1=CCCC1C(=O)NCc1ccc(C(=N)N)cc1)c1cc(Cl)ccc1C +CCNC(=O)C1OC(n2cnc3c(NC(=O)Nc4cccc(Cl)c4)nc(I)nc32)C(O)C1O +CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)c4cn5cc(C#N)ccc5n4)c3)sc2C1 +NC1=NC(CCc2ccc(Nc3cnc(Cl)nc3)cc2)CO1 +COc1cc(-c2cc(C3CCN(C4COC4)CC3)n(C(C)C)n2)cnc1N +Cc1csc(C#CC23CC4CC(C2)CC(NC(=O)c2ccn(C)n2)(C4)C3)n1 +Cc1nc[nH]c1CN1CCN(C(=O)NC(CC(C)C)C(=O)O)C(Cc2ccccc2)C1=O +COc1ccc(CCOc2c(I)cc(CC(N)C(=O)O)cc2I)cc1 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1(S(=O)(=O)c2cccc3ccccc23)CCCC1 +CN(C)CC=CC(=O)N1CCCc2[nH]c3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn3c2C1 +CN(C(=O)Nc1ccc(-c2ccccc2)cc1)C1CCN(C(=O)N(C)C2CCN(CCCc3ccc(Cl)cc3)C2)C1 +CS(=O)(=O)NC(=O)Cc1ccccc1Oc1ccccc1F +CC(CS(=O)(=O)c1ccc(Oc2ccccc2)cc1)(NCc1ccccc1)C(=O)NO +COc1ccc(-c2cc3nc(NC(C)C)[nH]c(=O)c3s2)cc1 +CN=C(N)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O +N#Cc1ccc(Oc2ccc(Cc3ccncc3)cc2O)c(Cl)c1 +CC(C)C(CN1CCCC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +Cn1ccc(-c2ccc(Cn3cc(C(=O)NC4CCCCC4O)c4ncccc43)cc2)n1 +O=C(NCc1ccc(Cl)cc1Cl)N1CCC(Oc2ccc(F)cc2)CC1 +Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3sccc3Cc3ccccc32)cc1 +CN1CCN(CC2CCCN2c2cc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)ccn2)CC1 +O=C(NCCCO)C1C(C(=O)Nc2ncc(Br)s2)C2CCC1C21CC1 +CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 +CCNC(=O)C1OC(n2cnc3c(NCc4ccccc4OC)ncnc32)C(O)C1O +CC1(C)Nc2c(cc(-c3cccn4nccc34)c3c2CCC3)C(C)(C)C1=O +Nc1nonc1C(=O)NN=C1c2ccccc2-c2nc3nonc3nc21 +COCC(NC(=O)Nc1cc2[nH]nc(OC)c2c(C)n1)c1ccccc1 +N#Cc1cccc(Cn2cccc2C=CC(=O)CC(=O)C(=O)O)c1 +CC(C)CC1C(=O)NC(C(=O)c2c[nH]c3ccccc23)Cc2ccc(cc2)OCCCCCC1C(=O)NO +CCSc1ccc(CNC2CCNCC2NC(=O)CNC(=O)c2cc(C(F)(F)F)ccc2N)cc1 +O=S(=O)(c1cccc(Cl)c1)N1CC2CC1CN2CCOc1ccccc1-c1ccccc1 +O=C(Nc1cc(-c2ccccc2)no1)c1ccc2cc3n(c2n1)CCCNC3=O +COc1cc(Br)c(-n2c(C)nc3c(-c4ccccc4C(F)(F)F)nc(C)nc32)c(OC)c1 +COc1ccc(N(CCCCCCC(=O)NO)c2ccccn2)nc1 +Cc1cccc(-c2csc(NC(=O)CCCCCCC(=O)NO)n2)c1 +CCCc1c(C(=O)Nc2cc(S(=O)(=O)N(C)C)ccc2C)cnn1-c1ccc(Cl)cc1 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+CN1C(=N)NC(C)(c2cc(-c3ccc(-c4nnco4)[nH]3)ccc2F)CS1(=O)=O +Cc1nc(-c2cc(Cc3ccc(S(C)(=O)=O)cc3)cnc2Nc2ccc(N)nc2)c2nc[nH]c2n1 +Cc1cccnc1-c1cc(N2CCC(NC(=O)CC(C)(C)O)CC2)ncc1Cl +COc1ccc(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc1 +CCC(=O)Nc1nc(-c2ccc3c(c2)OCO3)cc(-c2ccc3c(c2)OCO3)n1 +CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCCC4COc4cc(Cl)ccn4)ccc3N2C1 +CC(=O)c1nn(CC(=O)N2C(C(=O)Nc3nccc(C(F)(F)F)n3)CC3CC32)c2ncccc12 +CC(C)(C)OC(=O)N1CCC(Sc2ncnc3c2cnn3-c2ccc(S(C)(=O)=O)cc2)CC1 +COc1ccc2c(C#N)cn(-c3ccc(C(=O)O)c(O)c3)c2c1 +CN(C)CCn1nc2c3c(c(NCCC=CCCN4CC4)ccc31)C(=O)c1ccncc1-2 +O=C(O)C(=Cc1ccc(Oc2ccccc2Br)cc1)NC(=O)c1ccccc1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CO2)c1Cl +O=C(NCc1cc(Cl)ccc1-n1cnnn1)C1CCNN1C(=O)C(O)c1ccccc1 +O=S(=O)(c1ccc2[nH]c(-c3cc4ccccc4nc3O)cc2c1)N1CCNCC1 +CC1=C2CCc3cc(OCc4ccccc4Cl)ccc3N2CCC1=O +CC(C)Sc1nc(Nc2cccc(O)c2)c2cnn(CC(Cl)c3ccccc3)c2n1 +CC(c1ccccc1)(c1ccccc1)c1nc(-c2ccc(F)cc2)c(CC(=O)O)s1 +O=C(COC1CC(CNc2ccccn2)N(C(=O)OCc2ccccc2)C1)NCC(NS(=O)(=O)c1ccccc1)C(=O)O +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C#CCOCc1ccc2c3cccc4cccc(c5cccc1c52)c43 +COc1ccc(C(C#N)(CCCCCN2Cc3cc(OC)c(OCCn4ccnc4)cc3C2)Sc2ccc(C)cc2)cc1OC +CC(NC(=O)c1cc(C(=O)N2CCCC2C(F)(F)F)c2n1CCOC2)c1ccc(F)cc1 +CC(=O)c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1 +Cn1cc(C2=C(c3coc4ccc(F)cc34)C(=O)NC2=O)c2cc3c(cc21)OCO3 +NC(CC1c2ccccc2Oc2ccccc21)(C(=O)O)C1CC1(F)C(=O)O +COc1ccc(CNc2nnc(N3CC=CCC3)c3ccc(C#N)cc23)cc1Cl +CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCCCC2)c1 +CC(C)N1CCC(C(=O)Nc2cc(Oc3ccc4c(c3)nc(Nc3cccc(C(C)(C)C)c3)n4C)ccn2)CC1 +CN(C)CCCn1c(NC(=O)c2ccc3nc4n(c3c2)CCCNC4=O)nc2ccccc21 +CCCC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +CC1=C(c2cc(C(C)(C)N3CCCCC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CCCC1C +CCN(c1nc(C)cc(-c2c(C)cc(C)cc2C)n1)c1ccc(C(C)C)cc1Br +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)NCc5ccc(Oc6ccc(F)cc6)cc5)cn4c3)cc2)CC1 +CCC1(CC(O)(Cc2cc3c(C)cc(C#N)cc3[nH]2)C(F)(F)F)CCCc2ccccc21 +O=C1c2ccccc2S(=O)(=O)N1CCCCN1CCN(c2ccc(Cl)cc2)CC1 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+CNc1nc(-c2ccc3c(N)n[nH]c3c2)cc(N2CC(C(=O)Nc3ccccc3)CCC2C)n1 +O=C1c2c(ccc(O)c2O)CN1Cc1cc(Cl)c(F)cc1F +Cn1c2c(c3ccc(N4CCN(CCc5ccccc5)CC4=O)cc31)C1CCC(C2)N1 +CNc1nc(Nc2cc(OC)c(-c3nc(C)no3)cc2Cl)ncc1C(F)(F)F +O=S(=O)(c1ccc(C(F)(F)F)cc1)c1cccc2oc(N3CCNCC3)nc12 +Cc1c(CN2CCC(N3Cc4cccc(C(N)=O)c4C3=O)CC2)cnn1C +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(Oc2ccc(C#N)cc2)C1 +COc1cc2c3c(c4cc(O)ccc4c2cc1OC)CC1CCCN1C3 +c1ccc2nc(N3CC(Oc4nccnc4-c4ccc(OCC5CC5)nc4)C3)ccc2c1 +Cc1ccc(C(=O)N2CCC(F)(c3ccc(C#N)cn3)CC2)cc1NC(=O)c1ccc(NC(C)C)nc1 +COc1cccc(Cn2cc(C)c3cc(F)cc(C=CC(=O)NS(=O)(=O)c4ccc(F)c(F)c4)c32)c1 +CCNc1nc(Nc2ccc(C#N)cc2)nc(Oc2ccc3ccccc3c2Cl)n1 +COc1ccc2[nH]cc(CCNC(=O)CCCCCCNc3c4c(nc5cc(Cl)cc(Cl)c35)CCCC4)c2c1 +C=C(c1ccccc1)c1cc2c(cn1)C(C)(C)CN2C(=O)CN1CC(C)NCC1COC +Cc1cc(C)cc(Oc2ccc(CCC(=O)O)c(C(=O)NC(CC(C)C)c3cc(C)cc(C)c3)c2)c1 +CCC(=O)Nc1cc2c(Nc3ccc4c(c3)CCN4Cc3ccccc3)ncnc2cc1OC +CCOC(=O)c1c(CN(CC)Cc2ccccc2)nc2ccccc2c1-c1ccccc1 +Cc1cc2n[nH]c(=O)n2c2cc(-c3ccc(C(=O)N4CCOCC4)cc3)ccc12 +COc1cccn2c(C(=O)N3CCCCC3)c(C(F)(F)F)nc12 +O=P(O)(O)C(CCc1cccc(Oc2ccccc2)c1)S(=O)(=O)O +CNC(=O)c1ccccc1-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc21 +COc1cccc2c(C(=O)NC(C)Cc3ccccc3)c(C)n(CCN3CCOCC3)c12 +CCN(CC)C1CCN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCCC3)CNC5=O)nc2)CC1 +O=C(NCCCCCCNc1c2c(nc3ccccc13)CCCC2)c1cc2ccccc2o1 +C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC +Nc1nc(-c2cc(F)cc(F)c2)nc2sc(CN3CCOCC3)cc12 +COc1ccc(OCCN(CC(=O)NCc2ccccc2)Cc2ccc(F)cc2)cc1OC +Cc1cc(-c2c(C(N)=O)nc3n2CCOc2cc(F)c(C#CC(C)(O)c4noc(C)n4)cc2-3)[nH]n1 +Cc1nnc(CNc2c(F)c(OCC3CC3c3ccccn3)nc3ccnn23)s1 +Cc1[nH]n(-c2ccc(I)cc2)c(=O)c1N=Nc1c(O)cc(S(=O)(=O)O)c2ccccc12 +O=C(Nc1ccccc1-c1cn2c(CN3CCC(O)C3)csc2n1)c1ccc2ccccc2c1 +COCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCCCO)C(C)C)ccc1OC +O=c1c2c([nH]c3cc([N+](=O)[O-])ccc13)CCCC2 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 +Cc1ccc(F)cc1Cc1ccc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3NC3CCOCC3)c2c1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCC(C(=O)O)CC3)cc12 +CC(NC(=O)CC#N)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 +CCCCCCCCCCCCCCOc1ccc(C(=O)N(Cc2cccc[n+]2CCC)C(C)=O)cc1OC +COc1cc2c(cc1OC)-c1c3c(cc4c1C(C2)N(C)CC4)OCO3 +O=C(Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +OCC1OC(n2cnc3c(NCCCCc4ccccc4)ncnc32)C(O)C1O +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)O)C(CS)Cc1cccc(-c2ccccc2)c1 +O=C(Nc1ccc(C(=O)c2ccc(Cl)cc2)c(Cl)c1)C1=C(O)c2ccccc2S(=O)(=O)N1 +CCOc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCN(CCS(C)(=O)=O)CC4)nc12 +COc1cc(C)cc2cc(-c3c(CN4CCCC4)c(CN4CCNCC4)n4ncnc(N)c34)sc12 +COc1cc2cc(C)[nH]c2cc1NC(=O)c1cnn2cccnc12 +C=CC(=O)Nc1cccc(-n2c(-c3nc(-c4cnn(C5CCN(C)CC5)c4)cnc3N)nc3cnccc32)c1 +Cc1cccc(C)c1N1CC(CN2CCC(F)(F)CC2)(C(=O)Nc2cc(Cl)cc(C(F)(F)F)c2)C(C)C1=O +CC1CN(c2ccc(F)c(NS(=O)(=O)c3ccc(-c4ccoc4)cc3Cl)c2)CC(C)N1 +COc1ccc(CCn2c(=O)c3ccccc3c3nc4ccccn4c32)cc1 +CCN(CC)C(=O)c1ccc(N(c2cccc(CO)c2)C2CCN(Cc3ccccc3)CC2)cc1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CN(C)C)cn1 +CNC(=O)c1cncc(NC(=O)c2cc(NC(=O)c3cccc(C(C)(C)C#N)c3)ccc2C)c1 +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3)cc2n(C)c1=O +Cc1cccnc1CNC(=O)c1cc(-c2ccccc2Cl)nc(N)n1 +CNc1cc(Nc2nc3ccc(C(=O)Nc4c(C)cccc4Cl)cc3s2)ncn1 +O=c1cc(-c2cccc3ccccc23)oc2cc(OCCCCCCCCN3CCCC3)ccc12 +COc1cccc2c1CCCC2CN(C)CCc1ccc2c(c1)CCN2S(C)(=O)=O +Cn1c(=O)c2c([nH]c(=O)n2CCCCN2CCN(c3cccc(Cl)c3)CC2)n(C)c1=O +CC1(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)CS(=O)(=O)C2(CC2)C(=N)N1 +COc1cccc2c(NN3C(=O)C=C(C)C3=O)nc(-c3cccs3)nc12 +Cc1cc(-c2nc3cnc(Cl)cc3n2C(C)c2ccccn2)cn(C)c1=O +Nc1ncc(-c2cc[nH]c2)cc1C(=O)Nc1ccncc1 +c1ccc(CCCN2CCN(c3ccc4ccccc4c3)CC2)cc1 +CS(=O)(=O)c1ccc(C2(O)CCN(C(=O)c3ccccc3)C3CCCCC32)cc1 +CCC12C=CCN3CCC4(C(=C(C(=O)OC)C1)Nc1cc(OC)c(OC(C)=O)cc14)C32 +CN1CCN(C2=C(Cl)C(=O)N(c3ccc(Cl)cc3)C2=O)CC1 +CCC(C)C(S)C(=O)NC(Cc1cccc2ccccc12)C(=O)O +COc1cc(-c2cc(-c3c[nH]c4cc(F)ccc34)nc(N)c2C#N)cc(Br)c1OC +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc(Br)cn3)n[nH]c2C1(C)C +OC(COc1cccc2[nH]c3ccccc3c12)CN1CCC(Cc2cccnc2)CC1 +Cc1cc(C2CC2)c(-c2nc3c([nH]2)COCC3)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +O=C(NC1CCCCC1C(=O)O)c1cnn2c(O)cc(-c3ccccc3)nc12 +CN(Cc1nc2cccc(C(=O)N3CCN(Cc4ccccc4)CC3)c2[nH]1)C1CCCc2cccnc21 +CNC(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)c2C1 +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C1(C)Cc1ccc(Br)cc1 +C=CC(=O)Nc1ccc2ncnc(Nc3ccc(-c4ccccc4)cc3)c2c1 +COCCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2cc[nH]c2)cc1 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)c2cc1OCCN1CCCCC1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1CC(N)C(F)CCO1 +CC(=O)NC(CC(C)C)C1NC(C(=O)O)CC1c1nccs1 +CC(=O)c1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1 +CCN(CC)CCOc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(-c3ccccc3)n2)cc1 +CN1C(=O)C(=Cc2ccc3c(c2)OCO3)N=C1NCCN1CCOCC1 +Cc1ccncc1-c1ccc(COC2CCC(N3CCCCCC3)C2OCC=CCCC(=O)O)cc1 +O=C(O)CCn1c2ccc(O)cc2c2c3c(c(-c4c(Cl)cccc4Cl)cc21)C(=O)NC3=O +CC1CN(CC(=O)N2CC(C)(C)c3ncc(C(F)(F)CC4CC4)cc32)C(CN2CCOCC2)CN1 +Cc1cc(-c2nc(C)c(C(OC(C)(C)C)C(=O)O)c(-c3ccc4c(c3)CCCO4)c2C)ccc1Cl +CCSc1nc2cc(S(=O)(=O)NCc3ccc(F)cc3)ccc2n1Cc1ccccc1 +Cc1nc2c(C#N)cccc2nc1-c1ccc(-c2cccc(S(C)(=O)=O)c2)cc1 +COc1ncccc1-c1cc2c(C)nc(N)nc2n(C2CCCC2)c1=O +CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)CCC1O +CC(SCCc1c(CO)oc2c(OCC(=O)O)cccc12)(c1ccccc1)c1ccccc1 +Fc1ccc(-c2nn3ncccc3c2-c2ccnc(Nc3ccccc3)n2)cc1 +Nc1ncnc2c1c(-c1ccc[nH]1)cn2C1OC(CO)C(O)C1O +CC1Cc2c(-c3ccnn3C)nn(C)c2CN1C(=O)c1cccc(C(F)(F)F)c1Cl +Cc1ccccc1Nc1nc(Nc2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)nc(NC2CCCCC2)n1 +COc1cc(F)c(CN2C(=O)N(c3ccc(OC)c(OC)c3)S(=O)(=O)c3ccccc32)c(Cl)c1 +OC(CNCc1ccccc1OCc1ccncc1)c1cc(Br)cs1 +CCCCOC(=O)c1ccc(-n2nc(C=O)c3c2C(Cc2cccc4ccccc24)CCC3)cc1 +CCc1nn(Cc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c(=NC(=O)c2cccc(F)c2)s1 +O=C(Nc1ccc(-c2ccccc2)cc1)c1ccnn1CCc1ccncc1 +COc1cnc(C(=O)Nc2ccc(F)c(C3(C(F)F)N=C(N)OC4CC43)c2)nc1 +CC(Nc1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)c1ccc(F)c(F)c1 +CCCCc1cc(=O)n2nc(NCc3ccc(Br)cc3F)c(C#N)c2[nH]1 +CN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)c1ccc(CN2CCC(C(N)=O)CC2)cc1 +COc1ncccc1-c1cc(N2CCN(C)CC2)nc(N)n1 +CN(CC(O)CO)C(=O)c1ccncc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1 +CCOc1ccc2c(c1)OC(=Cc1cc[n+](Cc3ccc(F)cc3)cc1)C2=O +c1ccc2cc(CCCNCCCCCCCCCCNCCCc3ccc4ccccc4c3)ccc2c1 +CN1CCN(C(=O)C2(NS(=O)(=O)c3ccc4c(Cl)cnc(N=C(N)N)c4c3)CCCC2)CC1 +CC(C)(C)c1ccc(C(=O)Nc2ccc(CC(=O)O)cc2)o1 +Cc1nnc(SCC(=O)Nc2ccccc2Br)n1-c1cccc2ccccc12 +NS(=O)(=O)c1ccc(NC(=O)C=Cc2ccc(F)cc2)cc1 +CN(C)C1CCN(c2ccc3[nH]c(C(=O)c4ccnc(-c5cncc6ccccc56)c4)nc3n2)CC1 +COCC1CCCN1C(=O)c1cc(N)c2nc(-c3ccc(Br)o3)nn2c1 +NCc1ccc(Cl)c(NC(=O)CN2CCCCC(NC(=O)c3ccc(-c4ccccc4)cc3)C2=O)c1 +O=C(c1cccc2ccccc12)N(O)CCCP(=O)(O)O +COc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)C3=Cc2[nH]c(C)c(CC(=O)O)c2C)cc1 +O=C(O)CCCCCCC1=CCCC1NS(=O)(=O)c1ccc(F)cc1 +COc1ccccc1C1CCN(c2ccc(S(=O)(=O)C3(C(=O)NO)CCOCC3)cc2)CC1 +Cc1ccc(Cn2c(O)c(N=NC(S)=Nc3ccccc3F)c3ccccc32)cc1 +NS(=O)(=O)c1cc(F)ccc1NS(=O)(=O)C=Cc1ccc(-c2ccccc2)cc1 +CC(CO)NC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CC(CNC(=O)Cc1c(F)ccc(F)c1F)C1CCN(C(=O)OC(C)(C)C)CC1 +Cc1ccc(C(=O)NC2CCC2)cc1-n1cnc2ccc(N3CCN(C)CC3)cc2c1=O +COC1C(F)CN(C(=O)Cn2nc(C(N)=O)c3ccccc32)C1C(=O)Nc1cccc(Br)n1 +CN1CCc2nc(NC(=O)c3cccc(C4CNCC4C(=O)Nc4ccc(C#N)cc4)c3)sc2C1 +COc1ccc(NC2C3=C(OC2(C)C)c2ccccc2C(=O)C3=O)cc1 +Cc1c(Nc2c(C#N)cncc2-c2cc3cc(CN4CCOCC4)ccc3o2)ccc2[nH]ccc12 +O=C(CCCN1CCC(O)(c2cc3ccc2CCc2ccc(cc2)CC3)CC1)c1ccc(F)cc1 +CC(=O)Oc1ccc(C=CC(=O)Nc2ccc3c(c2)COC3=O)cc1OC(C)=O +CCNC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C2c3cc(Cl)cc(Cl)c3CC2O)C1 +O=C(NCCCCCN1CCCC2=CC3CC(CN4CCCCC34)C21)c1ccc(OC(F)(F)F)cc1 +COc1cc(OC)nc(OC(C(=O)O)C(OC)(c2ccc(F)cc2)c2ccc(F)cc2)n1 +NS(=O)(=O)c1ccc(Nc2ccnc(NS(=O)(=O)c3c(F)c(F)cc(F)c3F)n2)cc1 +Cc1c(F)cncc1-c1nc2cc(F)c(F)cc2n1C1CC1 +CCC(CO)N1C(=O)C(C)(C2CC2C(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cc1ccc(-n2nc(C3CCN(C)CC3)cc2NC(=O)c2cnn3cccnc23)nc1 +CC(C)(C)N=c1c(O)c(O)c1=NCc1ccc(C#N)cc1Cl +O=C(NCc1ncco1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(CC(Nc1ccc([N+](=O)[O-])cc1)C1CCCCC1)c1ccc(Cl)c(Cl)c1 +CC(Cc1ccc(OCS(=O)(=O)O)cc1)NCC(O)c1cccc(Cl)c1 +C#Cn1ccnc1C#Cc1ccc([N+](=O)[O-])cc1 +Cn1c(=O)c2c(nc3n2C(CC(=O)Nc2ccc(-c4ccccc4)nn2)CC3)n(C)c1=O +CCCNC(=O)OC1(C(=O)CO)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC21C +CN(Cc1cn(C)c2ccccc12)C(=O)C=Cc1cnc2c(c1)CCC(=O)N2 +CCCC(NC(=O)NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)C(=O)O +O=C(Nc1nc2ccc(Br)cc2s1)c1cc(Br)ccc1O +CC(=O)OCOP1(=O)OCC2OC(n3c(Sc4ccc(Cl)cc4)nc4c(N)ncnc43)C(O)C2O1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1c(Cl)nc2scc(C)n12 +N=C(N)c1ccc(-c2ccc3cc(-c4cnccc4C(=N)N)[nH]c3c2)cc1 +O=C(NC(c1cccc(Cl)c1)C1CCNCC1)c1ccc2cnccc2c1 +Cc1ccc2c(c1)c(-c1ccnc3ccccc13)c(C)n2CC(=O)O +O=c1c2ccccc2nc2n1CCC2=Cc1ccc(OCCCN2CCCCC2)cc1 +O=c1n(C2CCNCC2)nc(-c2ccnc(NC3CCOCC3)c2)n1-c1ccc2ccccc2c1 +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)N2CCC(C(=O)NCCN(C)C)CC2)sc2ccccc12 +CN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3CCCl)CC4)c2)CC1 +Cc1cc(-c2nnn(CC3CCC(CO)CC3)n2)cc(C(=O)NCc2cccc(F)c2)n1 +O=C(CCCc1c[nH]nn1)NC1CCN(C(=O)OCc2ccc(Cl)cc2Cl)CC1 +Clc1ccccc1Nc1ccnc(Nc2ccc(-c3nnn[nH]3)cc2)n1 +CN1CCN(S(=O)(=O)c2cccc(-c3cnc(N)c(C(=O)Nc4cccnc4)n3)c2)CC1 +COc1ccc(-c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C)cc3)n2)cc1OC +O=C(Cn1c(-c2ccccn2)nc2ccccc21)Nc1ccc(Cl)cc1 +O=C(O)CC(COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 +COc1cc(CNCC(C)C(=O)N(Cc2cc(Cl)c3c(c2)OCCCO3)CC(C)C)ccc1F +Cc1cc(-c2c(F)cc3c4nn(CCCN(C)C)c(=O)c-4cn(C4CC4)c3c2F)cc(C)n1 +CCCC(CO)NCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1F +COc1nccc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc12 +CCc1ccc(-c2cc3ncn(C4CCN(C(=O)N(C)C5CCN(C6CCOCC6)C5)C4)c(=O)c3s2)cc1 +COCc1ncn(C2=NCC(=O)N3CCc4c(ccc(F)c4C4CC4)C3=C2)n1 +CN(Cc1ccc(C(=O)O)cc1)CC1CCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1 +COc1cc(CN(c2ccc(C#N)cc2)n2cnnc2)cc(Cl)c1O +CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)cs1)C(=O)O +CN(C)CCCNc1c2ccccc2nc2c(Cl)ccc([N+](=O)[O-])c12 +C=CC(=O)Nc1nc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCN(C)CC1 +CN(c1ncc2cccc(-c3cc4c([nH]3)CCNC4=O)c2n1)C(C)(C)C +c1ccc(CCCCNCCOc2cccc3[nH]ccc23)cc1 +Cc1nc(C)n(-c2cc(C3CC3c3nc4ccccc4n3C)nc(N)n2)n1 +CC(C)c1ccc2nc3c(nc2c1)C(=O)c1ccncc1C3=O 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+COc1cccc(COc2ccc(OCCCC#N)c(C(C)=O)c2)c1 +C=CCN1CC(C)N(C(c2ccc(C(=O)N(CC)CC)cc2)c2cccc(I)c2)CC1C +CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(=O)Nc1ccccn1)CC(C)C +COc1c(C)c(C)c(Br)c(N)c1CC=C(C)CCC(=O)O +CC1CCC2C(C)C(OCc3ccc(CN4CCN(c5ccc(F)cc5)CC4)cc3)OC3OC4(C)CCC1C32OO4 +O=C(O)C=Cc1ccc(CN2CCCC2=O)cc1OCCc1ccc2ccccc2c1 +NC(=O)c1cccc(-c2ccc3c(c2)COCCN3c2ccc(C(F)(F)F)cc2)n1 +CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(I)cc12 +CC(C)(C)COC=NCCCOc1ccc(C(F)(F)F)cc1C(=O)N=c1sc(C(C)(C)C)cn1CC1CCCO1 +CCc1nc(-n2nc(Cc3ccccc3F)c3cc(F)ccc32)nc2c1C(C)(C)C(=O)N2 +CCOc1cc(C(=CC#N)c2ccc(N(C)C)cc2)ccc1OC +COCC1OC(OCCc2ccccc2)C(NC(=O)CCCN=C(N)N)C(OCc2ccc(Cl)cc2)C1O +c1ccc(N2CCN(CCC3OCCc4c3cnn4-c3ccccc3)CC2)cc1 +COc1ccc(C(=O)NC(C)c2cccc(C(=O)Nc3nc4c(s3)CN(C)CC4)c2)cc1C +COc1cc(C(=O)NC(=N)Nc2ccc(C)c(NC(=O)c3ccc(-c4ccc(F)cc4)cc3)c2)cc(OC)c1OC +CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC2CCCC(F)(F)C2)cc1F +CC12CCC(O)CC1CCC1C2CCC2(C)C1CCCN2C(=O)C(F)(F)F +O=C(c1cccnc1)N1CCC(NS(=O)(=O)c2cc(S(=O)(=O)c3ccccc3)ccc2C(F)(F)F)CC1 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+c1ccc(-c2cc3cccnc3nc2-c2ccc(CN3CCC(c4cc(-c5ccccn5)[nH]n4)CC3)cc2)cc1 +O=C(Nc1ccc(C(=O)N2CC3CS(=O)(=O)CCN3Cc3ccccc32)cc1)c1ccccc1-c1ccccc1 +CCN1CCC(c2ccc(-c3cc4ncn(C)c(=O)c4c(NC(C)C)n3)cc2)CC1 +CCCN(CCC)C(=O)Cc1c(-c2ccccc2)nc2ccc(OC)cn12 +N=C(N)c1ccc(-c2cc(-c3ccc(C(=N)N)nc3)on2)cc1 +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(CCc2ccccc2C(F)(F)F)CC1 +COc1ccc(-n2nc(C(F)(F)F)cc2C(=O)Cc2ccc(-c3ccccc3S(N)(=O)=O)cc2)cc1 +NC(=O)Nc1sc(-c2ccc(OCCN3CCCCC3)cc2)cc1C(N)=O +O=C(CCCSc1nnc(SCCCC(=O)c2ccc(F)cc2)s1)c1ccc(F)cc1 +O=S(=O)(NCCCCN1CCN(c2cccc(Cl)c2)CC1)c1ccc2ccccc2c1 +C#CCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3ccccc3)CC2)cc1 +O=C(NCc1ccc(F)cc1)c1ccc(=O)n(-c2ccc(Oc3ccnc4ccsc34)c(F)c2)c1 +Nc1cnc(-c2ccc(-c3ccccc3-c3cnc(N)nc3)cc2F)cn1 +O=C(NC1CCN(Cc2ccc3cc(F)ccc3c2)C1)c1ccc(F)cc1 +CC#CCC(C)C(O)C=CC1C(O)CC2Oc3c(CCCC(=O)O)cccc3C21 +COc1cc(C=CC(=O)NCCc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc(OC)c1O +Cc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)nc1 +O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccc(F)cc3)cc2-c2ccc(F)cc2)cc1 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+O=C(Cc1cccc2ccccc12)Nc1cn(C2CCC2)cn1 +CCOC(=O)c1cc2ccc(OC3CCCCCC3)cc2oc1=O +CCCc1c(OCCCOc2cc(O)c(-c3ccccc3)cc2CC)cccc1Oc1ccccc1Cc1nnn[nH]1 +O=C(Nc1cnc2ccccc2c1)c1cccc(-n2cnnn2)c1 +CCCCCCCCCCCCCCNC(=O)C1CSC(c2ccc(OC)c(OC)c2)N1 +CNC(=O)c1cc(Cl)c(Nc2ncc(C(F)(F)F)c(NC)n2)cc1OC +CC(=O)c1cn(CC(=O)N2CC(F)CC2C(=O)NCc2cc(-c3nnn[nH]3)cc(Cl)c2F)c2ccccc12 +CN(C)CCCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 +CC(C)c1nc2c(c(C3CCCCC3)c1C(=O)c1ccc(C(F)(F)F)cc1)C(O)CC1(CCC1)C2 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCC(N(C)C)C3)cc2c1=O +COc1ccccc1C(=O)OCC#CCSc1nnc(-c2cccc3ccccc23)o1 +CCC(=O)C1OC(c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)C(O)C(O)C1O +CCc1ccc(Cc2c(Cl)ccc3c2COC32OC(COC(C)=O)C(O)C(O)C2O)cc1 +COc1cc(Nc2nc3cccc(-c4ccc5ncccc5c4)c3o2)cc(OC)c1OC +COc1cc(-n2cncc2-c2ccc3c(ccn3C)c2)cc(OC)c1OC +COc1cc2nccc(Oc3ccc4nc(NC(=O)c5ccc(F)cc5)sc4c3)c2cc1OC +COCCOCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 +CC(=O)OCC1OC(Oc2ccc(C=NNC(N)=S)cc2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +CC(=O)Nc1cc(Oc2ccc(CNC(=O)Nc3cc(C)c(Cl)cc3OCCN(C)C)cc2C)ccn1 +CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(C(=O)O)ccc12 +CCCSC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +CC(NC(=O)c1ccc(C#Cc2ncccc2F)cn1)C(C)(C)O +CN1CC2CC(OC(=O)C(c3ccccc3)c3ccccc3)CC1C2 +CC1(N)CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1 +COc1cc(C=C2CCCCN3C2=NOCC3c2ccc(F)cc2)ccc1-n1cnc(C)c1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCN2CCOCC2)CCCC1)c1ccc([N+](=O)[O-])cc1 +COc1ccc2c(c1)C13CCN(CC4CC4)C(C2)C1Cc1sc(NC(C)=O)nc1C3 +O=S1(=O)C=Cc2cc(-n3nncc3-c3cccc(F)c3)ccc2O1 +Cc1c(C(=O)NCCCCCCCCNC(=O)c2ccccc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(Nc1ccc(O)cc1C(F)(F)F)c1cc(NC2CCCCC2)ncn1 +COCCOCOc1cc(C)c(-c2ccc3cc(C(=O)O)ccc3c2Cl)cc1C12CC3CC(CC(C3)C1)C2 +CNc1ccccc1C(=O)OC1C(C)=CC23C(=O)C(C=C(CO)C(O)C12O)C1C(CC3C)C1(C)C +Cc1cc(C)c2nc(-c3cnc(NCCCC4CCN(C)CC4)nc3C)[nH]c2c1 +Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCNC1CCCC1 +COC12COC(c3ccc(Cl)c(Cc4ccc(OCCOC5CC5)cc4)c3)(O1)C(O)C(O)C2O +O=C(C1CCN(Cc2ccncc2)CC1)N1CCC2(CC1)C(=O)NCN2c1ccccc1 +COc1ccccc1N1CCN(CCCNC(=NC#N)c2ccccn2)CC1 +CN(C)Cc1nnc(-c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)[nH]1 +O=C(Nc1ccc(O)cc1O)c1ccc2c(-c3nc4ccccc4[nH]3)n[nH]c2c1 +CC(C)CC(Nc1ccc(C(=O)NCCC(=O)O)cn1)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1 +COC(=O)c1sc(C(C)(C)C)cc1NC(=O)Nc1ccc(Cl)cc1 +CCC(CC)c1nc(-c2ccc(OCCCN3CCCN(C(=O)C(C)NC(=O)c4ccco4)CC3)cc2F)no1 +CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCCN2CCNC(COC)C2)cc1 +Cc1cc(-c2c(-c3cccc(OC(F)(F)F)c3)cc3n2C(CCN)CNC3=O)ccc1F +N=C(NO)c1cccc(C#Cc2c(N)ncc3ccc(Cl)cc23)c1 +COc1ccc(Cn2cnc3c2CC(C(=O)O)N(C(=O)C2(c4ccccc4)CCCC2)C3)cc1C +COc1cccc(-c2nn(C(C)C)cc2C(=O)Nc2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)c1 +CC(C)C(Cc1ccc(C(F)(F)F)cc1)C(=O)NCC1(C2CC2)NC(=O)NC1=O +NCc1cccc(C2CCN(C(=O)c3ccc(C#Cc4cccs4)o3)CC2)c1 +COC(=O)CCCCN(C(=O)C(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +COc1ccc(CCC(=O)O)cc1-c1cc2c(cc1C)C(C)(C)CC(=O)N2C(C)C +NCC(=O)Nc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +CCc1cc(Cc2cnc(N)nc2N)cc(CC)c1OCCOCc1ccccc1 +CN1CCc2nc(C(=O)NC3CC(C(=O)O)CCC3NC(=O)c3cc4cc(Cl)ccc4[nH]3)sc2C1 +COc1ccc(Cl)cc1N1CCN(C(=O)c2oc(C)nc2-c2ccccc2F)CC1 +Cn1cc(-c2cnc3nnn(CC4CN(c5ncc(C6CCN(CCO)CC6)cn5)CCO4)c3n2)cn1 +CC(C)CNC(=O)c1ccc(-c2ccc(-c3ccccc3)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +N#Cc1cccc(-c2ccc3c(c2)CCN(CC(=O)Nc2ccc(F)c(Cl)c2)C32CCN(CC3CC3)CC2)c1 +CCCCC1CN(Cc2c[nH]c3c(N)ncnc23)CC1O +C=C(C)C1CCC(C)=CC1c1c(O)cc(CC2CN(C(C)=O)C2)cc1O +COc1cc(Nc2cc(C(F)(F)F)cn(C(C)c3ccc(F)cc3)c2=O)ccc1-n1cnc(C)c1 +CCC(CC)Nc1c(C)nc(-c2c(C)cc(C)cc2OC)nc1OC +COC1C(F)CN(C(=O)Cn2nc(C(C)=O)c3ccccc32)C1C(=O)Nc1cccc(Br)n1 +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)C1CC1 +COc1ccccc1-c1[nH]c2ccc(C)cc2c1CCC(=O)N1CCN(c2ccccc2OC)CC1 +COc1ccc(C2C(c3ccc(C)cc3)CC3CCC2N3C)cc1OC +CC(C)(C)Cc1cnc2c(c1)C(NCC(O)C1Cc3cccc(c3)CCCn3cc(ccc3=O)C(=O)N1)CC1(CCC1)O2 +COc1ccc(Oc2cc(NCCC(F)(F)F)c3ncn(-c4ccc(C(=O)NC5CC5)c(C)c4)c3c2)c(F)c1 +Cc1nc2ccc(Nc3nc(NCCN4CCOCC4)nc(Nc4ccc(F)cc4)n3)cc2n1Cc1ccccc1 +COC(=O)C=Cc1cccc(N(Cc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)C(=O)C2CCCCC2)c1 +CSCCC(NC(=O)c1cccc2c(NCC(N)CS)cccc12)C(=O)O +CCc1c(C)nc(O)c(NCc2nc3ccccc3o2)c1C +O=c1ccn(C2C(O)C(O)C3(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)CC23)c(=O)[nH]1 +CCN1CCCC1CNC(=O)c1c(O)c(Br)cc(N)c1OC +Cc1ccc(N2CCc3ncnc(NC(C)c4cccc(F)c4)c3C2)nc1 +CNc1ncnc2c(Nc3ccccc3C)nc(N3CCNCC3)nc12 +Cc1cc(CN2CCN(C)CC2)ccc1C(=O)Cn1ncc(OCc2ccc(Cl)cn2)cc1=O +CC1=C(c2nc(-c3ccc(C#N)cc3)cs2)C(c2ccc(Oc3ccccc3)nc2)NC(=O)N1 +Cc1cc(-n2ccc(N3CCNC3=O)n2)c2c(n1)N(c1ccc(OC(F)(F)F)cc1C)CC2 +CN1C(=O)CC2CN(CC(=O)Nc3ccc4c(c3)CC3(C4)C(=O)Nc4ncccc43)c3cccc1c32 +Cc1noc(-c2cc3cc(-c4cc(C(=O)NCc5ccc(C(=O)O)cc5)ncc4C)ccc3[nH]2)n1 +CCCCCCCCc1ccccc1CCCCCCCC(=O)C(F)(F)F +CCCS(=O)(=O)NCc1ccc2c(c1)CC(C(=O)N(C)C(CN1CCC(O)C1)c1ccccc1)O2 +Nc1nc2c(-c3ccc(C(F)(F)F)cc3)cccn2n1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCC(O)CF +COc1cccc(-c2cccc(C3(C)COCC(N)=N3)c2)c1 +O=C(c1cc(-n2ccc3ccccc32)c(O)cc1O)N1CCc2ccccc2C1 +Cc1cc(-c2c(C(N)=O)c3cc(F)c(OC(F)F)cc3n2C2CCCCC2)ccc1NS(=O)(=O)C(C)(C)C +Clc1ccc(-c2nn(Cc3ccccc3)c3c2CNCC3)cc1 +CC(=NOCC(=O)O)c1ccc(Sc2cc(F)cc(C3CCOCC3)c2)cc1 +C=CCn1c(=O)c(-c2cccc([N+](=O)[O-])c2)nc2ccccc21 +O=C(Cc1ccc2c(c1)OCO2)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +CC1C=C2CC(O)CCC2(C)C2CCC3(C)C(CCC3(C)O)C12 +O=c1ccc(Cc2ccc(Cl)c(Oc3ccccc3)c2)n[nH]1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(NC(=O)CN(CCOC)CCOC)cc3)ncc2F)c1 +Fc1ccccc1-c1ccc2[nH]nc(-c3cncc(OC4CNCCC45CC5)n3)c2c1 +CC#CCOc1ccc(C(=O)Nc2csc(C34COC(C)CC3CSC(N)=N4)n2)nc1 +Cc1cnc(N2CCC(c3coc4c(N5CCc6cc(S(C)(=O)=O)ccc65)ncnc34)CC2)nc1 +O=C(CCc1ccc(-c2ccccc2Cl)cc1)N1CCCC1c1ncc(-c2ccccc2)[nH]1 +CCc1ccccc1-c1ccc(-c2cc(NCCC(=O)O)c3ccccc3n2)cc1 +N=C(N)NC(=O)c1ccc(N2CCC(NC(=O)c3ccc[nH]3)C2)c(C(F)(F)F)c1 +O=C1OC2(CCC(c3nc4cc(Br)ccc4[nH]3)CC2)c2ccccc21 +CC(CF)N1CCC(OC(=O)C(O)(c2ccccc2)c2ccccc2)CC1 +Cc1cc(=O)n2nc(-c3ccccc3)n(Cc3ccc(F)cc3)c2n1 +CN1CCN(C2CCN(C(=O)c3cc4cc(Nc5nccc(-c6cn(C)cn6)n5)cc(Cl)c4[nH]3)CC2)C1=O +COc1ccc(C2(O)c3ccccc3C3=NCCCN32)cc1OC +Cn1c(OC2CCN(C(=O)OCc3ccccc3)CC2)nc(-c2ccncn2)cc1=O +CC1CCCC(C=CC2C3CCCCC3CC3C(=O)OCC32)N1C +CCOC(=O)c1ccc(-n2ccnc2)c(NC(=O)c2cccc(Br)c2)c1 +CN1CC2(C1)C(=N)NC(C)(c1cc(NC(=O)c3ccc(OC(F)F)cn3)ccc1F)CS2(=O)=O +CCOc1ccn(-c2ccc(F)cc2)c(=O)c1C(=O)Nc1ccc(Oc2ncnc3[nH]ccc23)c(F)c1 +CC1CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)CC(N)C1OCCS(C)(=O)=O +COc1ccc(-c2cc(C(=O)Nc3ccc(C4CNCCO4)cc3)[nH]n2)cc1OC +O=C(O)C(=O)CC(=O)c1ccc2c(c1)c(=O)c(C(=O)CC(=O)C(=O)O)cn2Cc1ccc(F)cc1 +CCCCCc1c(N)nc2ccccc2c1Cc1cccc(CN)c1 +O=C1CC(c2ccco2)=NCC2(CN3CCC2CC3)N1 +COc1cc(C(=O)NN=C2C(=O)N(CN3CCOCC3)c3ccc(C)c(Br)c32)cc(OC)c1OC +Cc1ccnc(Nc2nc3cc(C4(O)c5ccccc5C(=O)N4c4cccc(Cl)c4F)ccc3[nH]2)n1 +CCN(CC)CCNC(=O)c1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +COc1ccc(Br)c(C(=O)N2CCN(c3ccc(C(=O)NCCCc4ccccc4)cn3)CC2)c1 +COC1=CC2ON(c3cnoc3C)C(C1=O)C1=C2c2c(cc(OC)c(OC)c2OC)CCC1NC(C)=O +COc1cccc(CNC2CCN(S(=O)(=O)CCC3CCc4ccccc4N3S(=O)(=O)c3ccc(OC)cc3OC)CC2)c1 +CN1CCN(c2ccc([N+](=O)[O-])c(NCCc3ccccc3)c2)CC1 +COc1ccc(CCCNCCOc2cc(F)cc3c2OC(C)CC3)cc1 +COc1cc(-c2ccc3c(c2)Nc2ccccc2NC3=O)ccc1C#N +CC(C)C(S)C(=O)NC1(C(=O)NC(Cc2ccc(-c3ccco3)cc2)C(=O)O)CCCC1 +COC(=O)c1ccc(NC(=O)Nc2ccc(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)cc2)cc1 +COc1c(F)cccc1-c1noc(C2CCN2C(=O)c2ccc(C)cc2-n2nccn2)n1 +COCCOc1cc2ncnc(NC3=CC(=O)C(Cl)=C(OC)C3=O)c2cc1OC +O=C1CC(NC(=O)C2COCC3CC=CCC(NC(=O)c4nccc5ccccc45)C(=O)N32)C(O)O1 +O=S(=O)(c1ccc(F)cc1)N(Cc1ccc(F)c(C(F)(F)F)c1)c1nc2ccccn2c1Cl +CN1CC2CN(C(=O)Cn3cc(NC(=O)c4c(N)nn5cccnc45)c(-c4cc(Cl)ccc4OC(F)F)n3)CC2C1 +CCCCCCCCCCCCCCCCCC=CCCC=CCCCC(=O)O +OCCN(CCO)c1ccc(C=C2CCCN=C2c2cccnc2)cc1 +CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3N)cc2)cc1 +Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2ccccc2)c1=O +COc1ccccc1N1CCN(Cc2cn(C3OC(CO)C(O)C(O)C3F)nn2)CC1 +O=C(C=Cc1c[nH]cn1)N1CCC(n2c(CC3CCCC3)nc3cccnc32)CC1 +CCCCCCCCCCOC(=O)c1ccccc1CS(=O)(=O)NC1CCCCN(CC(=O)NC2CCCN(C(=N)N)C2O)C1=O +Cc1cc(-c2ccc(O)cc2Cl)sc1-c1ccc(O)cc1Cl +COCCOCCOCCOCCOC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CCC2)C1O5 +CC(Nc1c(-c2c(F)cc(OCCCO)cc2F)c(Cl)nc2ncnn12)C(F)(F)F +CC(C)(C)NC(=O)N1CC=C(c2cn(-c3ccccc3F)nn2)CC1 +Cc1ccc2c(NCc3ccc(NC(=O)C4CCN(Cc5ccc(F)cc5F)CC4)cc3)nc(N(C)C)nc2c1 +COCc1c(-c2nc(-c3cc(F)ccc3F)no2)cnn1-c1ccccc1 +COc1cccc(-c2cc(=O)c3cc(OCCCCCN4CCC(O)CC4)ccc3o2)c1 +CNC1CCN(c2nc(N)nc3c2oc2ccc(Cl)cc23)C1 +C#COc1ccc2c(c1OC)-c1ccc3c(c1C(CC=C)O2)C(C)=CC(C)(C)N3 +COc1cc(F)c(CC(=O)N2CCN(c3nc(Nc4cc(C)n[nH]4)c4cccn4n3)CC2)c(F)c1 +CN(C)C(=O)CN1CCn2c(nc(C(=O)NCc3ccc(F)cc3)c(O)c2=O)C1(C)C +CC1CC1c1cc(NC(=O)Nc2ccc(F)cc2)n(-c2ccccc2)n1 +COc1ccc(-c2nc(C(=O)c3ccc(F)cc3)c[nH]2)cc1 +CCC(CC)(CC(=O)Nc1cccc(OCc2ccc3cc(C)ccc3n2)c1)C(=O)O +Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCC(C)C3)cc2)c2ccc(O)cc12 +Cc1cc(C#N)cc(C)c1Nc1nc(NC2CCN(c3cccc(C(N)=O)c3)CC2)ncc1Br +COc1ccc(C(CO)Nc2ncnc3c2CN(c2ccc(Cl)cc2C#N)CC3)cn1 +Cc1c(O)ccc2c1oc(=O)c1c(C)ccc(C)c12 +O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccs1 +CN1CCC(c2c(O)cc(O)c3c2OC(=Cc2ccc(S(N)(=O)=O)cc2)C3=O)CC1 +CC(OCC1(c2ccccc2)CN(C)C(=O)N1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)NC3CCCCCCC3)nc12 +CCOP(=O)(OCC)C(NC(=O)C(C)Oc1ccc2c(c1O)C(=O)c1ccccc1C2=O)c1ccc(Br)cc1 +O=C1CC(c2ccccc2)CC(O)=C1Sc1ccccc1[N+](=O)[O-] +O=C(c1c2ccccc2cc2ccccc12)N1CCC(N2CCCC(C(=O)N3CCOCC3)C2)CC1 +O=C1CNC(=O)N1Cc1cccc(CCCCOCCCCCCNCC(O)c2ccc(O)c(CO)c2)c1 +CCN1CCN(c2cn(S(=O)(=O)c3ccc4ccccc4c3)c3cc(Cl)ccc23)CC1 +Cn1cnc2cc(-c3ccc(C(C)(C)O)nc3)nc(OCc3ccncc3)c2c1=O +O=c1c(-c2ccc(F)cc2)c2ccccn2c(=O)n1CCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +CCCCCCCCOC(=O)c1cc(O)c(=O)c2c(O)c(O)c(OC)cc2c1 +CCC(C1CC1)n1nc(C)nc(Nc2cc(C)c(C#N)cc2C)c1=O +CC1C2CCC3C4CC=C5CC(N(C)C(=O)c6ccc(C#N)cc6)CCC5(C)C4CCC32CN1C +COc1cccc(Oc2ccc3c(NCCCNCc4cccc(OC)c4O)ccnc3c2)c1 +COc1ccc(-c2c[nH]c3ncc(-c4cnc(N)nc4)cc23)cc1OC +O=C(O)C1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(-c2ncccn2)cc1 +Cc1ccc(C2CC2COc2nc(C)ncc2-c2ccc(=O)n(CCC#N)c2)nc1 +CCCCCC1(CCCCC)NC(c2nc(-c3ccccc3)c[nH]2)Cc2c1[nH]c1ccc(C)cc21 +CC(C)CC(NC(=O)c1cc(NCc2ccncc2)ccc1-c1ccccc1)C(=O)O +COc1ccc(NC(=O)c2coc(C3C4CCC(O4)C3Cc3ccccc3CCC(=O)O)n2)cc1 +Cc1cccc(-c2noc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)n2)c1 +CCCCc1nc2cc(C=CC(=O)NO)ccc2n1CCN(C)C(C)C +CC(=O)NC(C)c1ccc(OC2CCN(c3cc(OC4CCC4)ncn3)C2)cc1 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+Cc1cnccc1-c1cc(C(F)(F)F)cc(C2(C(C)C)C(C#N)=C(N)Oc3n[nH]c(C)c32)c1 +O=S(=O)(Nc1nccs1)c1cc(F)c(Oc2ccc(OC(F)(F)F)cc2-c2cn[nH]c2)cc1F +CCCC[S+]([O-])c1sc2nc(-c3nccs3)cc(-c3ccc(OCCO)cc3)c2c1N +CNc1ncnc2c1ncn2C1SC(C(=O)NC2CCCC2)C(O)C1O +CNc1nn2c(C)c(CN)c(C)nc2c1S(=O)(=O)c1cccc(F)c1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NC1CCN(C(=O)C2CCC2)c2ccc(Cc3ccccc3)cc21 +Cc1ccc(C(=O)N2CCOCC2Cc2cc(-n3nccn3)ccc2Cl)c(-n2nccn2)c1 +CC(C)C1CCC(N2CCC(N3C(=O)Cc4ccccc43)CC2)CC1 +Cn1nc(C(C)(C)C)c(C#N)c1-c1nc2cc(-c3ccccc3C(F)(F)F)nc(N3CCCCC3)c2[nH]1 +COc1ccc(NC(=N)c2cc(Br)cs2)cc1CSC1CCCC1 +c1nc(CC2CCN(CCCOc3ccc(OC4CCCCC4)cc3)CC2)c[nH]1 +CC(CSC(=O)C(C)(C)C)C(=O)N(CC(=O)O)C1CCCC1 +CC(=O)N1CCC(n2cc(Nc3ncc4c(n3)-c3c(nn(C)c3-c3ccc(OC(F)F)cc3)CC4)cn2)CC1 +COc1ccccc1N1CCN(CCCN2C(=O)CC3(CCc4ccccc43)CC2=O)CC1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CCOc3ccccc31)CC2 +CC(C)NC(=O)N1CCC(NC(=O)Nc2nc3nn(C)cc3c3nc(-c4ccco4)nn23)CC1 +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OCC6CCCO6)ccn5)n4)ccc3[nH]2)CC1 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+Fc1ccc(C(OCCN2CCN(CCCc3cccnc3)CC2)c2ccc(F)cc2)cc1 +O=C(O)C1CCCC1C(=O)c1ccc(-c2ccc(Nc3nc4ccc(F)cc4s3)c(F)c2)cc1 +COC(=O)c1c[nH]c2cc(N3CCN(c4ccccc4)CC3)c(OC)cc2c1=O +CC1CN(C(=O)c2sc3ccccc3c2OCc2ccccc2)CC(C)O1 +Cc1ccc(OCCNc2nc(Nc3cc(C)[nH]n3)cc(C)c2C#N)c(C)n1 +Fc1ccc(C2CN(Cc3ccc(Cl)cc3)CCC2c2cc(-c3ccc(Cl)cc3)n[nH]2)cc1 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2cnc(C(F)(F)F)cn2)CC1c1ccc(F)cc1F +Cc1cc(C(=O)Nc2ccc(N3CCOCC3=O)cc2F)n(-c2cc3ccccc3cc2F)n1 +Cn1nc(C2CC2)cc1Nc1ncc(Cl)c(NC2CC3CN(C(=O)CC#N)CC3C2)n1 +Cc1cc(C)c(S(=O)(=O)NC(Cc2ccc(-c3cccc(NC(=O)c4ccncc4)c3)cc2)C(=O)O)c(C)c1 +COC1CN(c2cc(-c3n[nH]c4ccc(-c5cnn(C)c5)cc34)ncn2)CC1O +CCc1nc(N)nc(NCCO)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1 +COC1=CC(=O)C2(C=C1OC)OCC1Oc3c(ccc4c3C=CC(C)(C)O4)C(=O)C12 +CCC=CC(CC)CC1(C)CC(CC)C(CCOC(C)=O)OO1 +O=C(NO)C1CCCCN1S(=O)(=O)N1CCN(c2ccccn2)CC1 +Cc1ccc(C#Cc2cc(Br)cc([N+](=O)[O-])c2)nc1 +NC(=O)c1ccc2c(c1)CCOC2CCN1CC=C(c2c[nH]c3c(F)cccc23)CC1 +O=C(Nc1cc[nH]c(=O)c1)c1cc(Cl)ccc1Oc1ccc(F)cc1 +CSCCC(NC(=O)CN1C(=O)N(Cc2c[nH]cn2)C(=O)C1(C)c1cccc2ccccc12)C(=O)O +COc1cc(F)ccc1N1CCN(CCCNc2ncccc2C(=O)N(C)C)CC1 +COc1cc(Cc2cnc(N)nc2N)cc2c1NC(C)(CF)C=C2CF +CC(C)C(C(=O)N1Cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2C1)c1ccccc1 +COc1cc(O)c2c(c1)C=CCC(O)C(O)C=CC(C)CNC2=O +CC(=O)c1cccc(CN2CCCC(CCC(=O)NCc3ccccc3F)C2)c1 +CCOc1ccccc1N1CCN(CCCCCn2cnc3sc(C)c(C)c3c2=O)CC1 +CCN1C(=O)c2c(nc(OC)n2Cc2ccc(OC)c(Br)c2)N2CC(Cc3ccccc3)N=C12 +C#CCn1c(=O)c2c(-c3cncn3C)n(Cc3ccnc4ccc(Cl)cc34)nc2n(CC2CC2)c1=O +Cc1ccc(S(=O)(=O)n2cc(C3(O)CC(CC#N)OC3=O)c3ccccc32)cc1 +CNC(=O)c1cc2c(Oc3ccc(C(F)(F)CO)cc3)cncc2s1 +Cn1c(OC2CCN(c3ccccc3)CC2)nc(-c2ccncn2)cc1=O +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4c(C(=O)O)cccc43)s2)c1 +CC(C)N1CCN(C(=S)c2ccc(CN3CCCCC3)nc2)CC1 +COC(=O)C(C)Sc1ccc2nnc(-c3cccs3)n2n1 +CC(C)NC(=O)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)CCOCCO +Cc1cc(NC(=O)NCc2cc(Cl)cc(Cl)c2)ccc1N1CCC(N2CCCC2C)C1 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1ccccc1 +Fc1ccc(F)c(-c2ncoc2-c2ccc3nnc(C4CCC4)n3c2)c1 +O=C(c1csc2ccccc12)N(Cc1ccccc1)C1CCC2(CC1)OCCO2 +CN(CCN1CCN(c2cccc(Cl)c2)C1=O)CC12CCC(CC1)C2(C)C +FC(F)(F)CN(Cc1sc(Nc2c(Cl)cc(Cl)cc2Cl)nc1C(F)(F)F)CC1CC1 +COc1cccc(C(CC(C)C)NC(=O)c2cc(COc3cccc(C#N)c3)ccc2CCC(=O)O)c1 +Cc1cc(C)c(S(=O)(=O)N(Cc2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)Cc2c(F)cccc2Cl)c(C)c1 +CC(=O)N1CCN(c2ccc(NC(=O)c3nnc(Nc4ccccc4F)o3)cc2)CC1 +Cc1ccc(COc2ccc3c(c2)no[n+]3[O-])cc1 +NS(=O)(=O)c1cccc(N2C(=O)c3c(Br)c(Br)c(Br)c(Br)c3C2=O)c1 +CCCCCCCCC(=O)NCc1ccc(OCC(O)CNCC)c(OC)c1 +CC(c1ccccc1)N(CCCc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21)C(=O)C(C)(C)C +O=C(CCc1ccccc1)NCc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1 +Cc1nc2cc(Cl)ccc2c(-c2ccc(Cl)cc2)c1C(OC(C)(C)C)C(=O)O +CCOc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)O)n2Cc1ccc(F)cc1F +CN1CCC(OC(=O)N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccccc4)n3)CC2)CC1 +Nc1ccccc1NC(=O)CCCCCNC(=O)c1ccc[nH]1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCc3cccc(F)c3)[nH]c3ccc(Cl)cc23)c1 +COC(=O)C(C)N1C(=O)SC(=Cc2ccc(O)c(Cl)c2)C1=O +C=CC1(C)CC(=O)C2(O)C(C)(O1)C(O)C(OC(=O)NCCc1ccccn1)C1C(C)(C)CCC(O)C12C 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+O=C(Nc1cc(C(=O)N2CC3CNC3C2)nn1-c1ccccc1)c1cc(-c2ncccc2F)c(Cl)cc1Cl +CN(C)c1ncnc2sc3c(=O)n(-c4ccc(F)cc4)cnc3c12 +CC(N)C(=O)N1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 +CNC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(CCN1C(=O)c2ccccc2C1=O)C(=O)O +Cc1ccn(-c2nc(-c3nnc(Cc4ccc(F)cc4)o3)c(O)c3ncccc23)n1 +O=S(=O)(c1cccc(C(F)(F)F)c1)c1cccc2oc(N3CCNCC3)nc12 +O=C(Nc1cccc(Br)c1)Nc1cccc2ccc(O)cc12 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OC)c(OC)c3)oc2c1 +CN(C)S(=O)(=O)N1CC(F)CC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +COc1ccc(S(=O)(=O)C(Cc2ccc3ccccc3c2)C(=O)NO)cc1 +O=c1[nH]c2ccc(OC3CCN(Cc4ccccc4)CC3)cc2c2c1CSCC2 +CNCCC(c1cccc(F)c1)N1C(=O)C(C)(C)c2cccc(F)c21 +COc1cc(-c2ccccc2Oc2ccc(S(=O)(=O)Nc3nccs3)cc2C#N)ccc1C#N +CCCCC(C)(C)C(O)C=CC1CCCC(=O)N1CCSCCCC(=O)O +Cc1ccc(Oc2ncccc2C(=O)NCC(O)CN2CCN(c3ccccc3OC(C)C)CC2)cc1 +COC(=O)C1C(O)C2(O)c3c(OC)cccc3OC2(c2ccc(OC)cc2)C1c1ccccc1 +O=C1c2ccccc2C(=O)c2c(-c3cccnc3)noc21 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2ccc1CCc1ccc(cc1)CC2 +O=C(Nc1cn2nc(-c3cn(C4CC4)nc3-c3ccc(F)cc3)ccc2n1)c1ccc(C(F)(F)F)nc1 +COc1ccc2ccc3occ(CNC(=O)C4CC4)c3c2c1 +Cc1nc2ccc(CN3CCOCC3)cc2n2c(-c3c(F)cccc3Cl)nnc12 +N#CC1CCN(C(=O)OCC(F)(F)CO)CC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +CCCCN1CCC(COc2nc3ccccc3c3c2CCCCN3)CC1 +Nc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +c1ccc(COCCCOc2ccc(C3C(Cn4cncn4)CNCC3OCc3ccc4ccccc4c3)cc2)cc1 +CC(=Nc1ccc2c(c1)C(NC(=O)c1ccc(Br)cc1)C(O)C2)Nc1ccc(F)cc1 +CC(=O)NCCc1c2n(c3ccc(Cl)cc13)CCCc1ccccc1-2 +Cc1ccc(CCNc2c(C(=O)OCC3CC3)cnc3c2cnn3CC(Cl)c2ccccc2)cc1 +CCOC(=O)c1oc2cnccc2c1Nc1ccc2ccccc2c1 +Cc1[nH]c2cc(C3CCCCN3C(=O)c3cc(F)ccc3NS(C)(=O)=O)nn2c(=O)c1C +COc1cc(OC)c(C=CC(=O)C(=Cc2ccc(O)c(F)c2)C(=O)C=Cc2c(OC)cc(OC)cc2OC)c(OC)c1 +CN(C(=O)C=Cc1ccccn1)C1CCC2(O)C3C(O)c4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +O=c1[nH]c(N2CCOCC2)nc(NC2CCNC2)c1-c1nc2ccccc2s1 +CCOc1cc(=O)n(C)cc1-c1cc(N(Cc2cnccn2)S(=O)(=O)CC)ccc1Oc1ccc(F)cc1F +CN1CCN(Cc2ccc(C(=O)NN(CC3CC3)c3nc(C#N)ncc3Br)cc2)CC1 +Cc1cccc(Cn2nnc3c(-c4ccco4)nc(N)nc32)c1 +CN(C1CCc2c(c3ccccc3n2CCC(=O)O)C1)S(=O)(=O)c1ccc(F)cc1 +CNC1C(O)C(OC2C(N)CC(N)C(OC3OC(CN)C4OCOC4C3N)C2O)OCC1(C)O +O=C(OC1C[N+]2(CCc3ccccc3)CCC1CC2)C(O)(c1cccs1)c1cccs1 +COc1cc(N)cc(-c2cnc3[nH]cc(-c4ccncc4)c3c2)c1 +O=C(O)c1ccc(N2CC3(CCN(Cc4cc5c(cc4-c4cc(F)c(F)cc4F)CCC5)CC3)OC2=O)cc1 +CCOc1cc2c(c(F)c1OCC)C(=N)N(CC(=O)c1cc(N3CCC(O)CC3)c(OC)c(C(C)(C)C)c1)C2 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCCCN1CCOCC1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CC(NC(=O)c2ccccc2)c2ccccc2)CC1 +Cc1ccccc1NC(=O)Nc1ccc(-c2cccn(Cc3ccc(C(=O)O)cc3)c2=O)cc1 +N=C(NC1CCCN2c3cc(Cl)ccc3Oc3ccccc3C12)C(F)(F)F +Nc1n[nH]c2cc(-c3nc(C(Cc4ccccc4)NC(=O)NCc4cc(Cl)ccc4-n4cncn4)[nH]c3Cl)ccc12 +C=CC(=O)Nc1cc(C(=O)N(C)C)ccc1Nc1cc(N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)ncn1 +CN1C2CCC1CC(NC(=O)NC(=O)c1ccccc1OCC1CC1)C2 +O=C(Nc1cccc([N+](=O)[O-])c1)Nc1cccc2ccc(O)cc12 +[C-]#[N+]c1ccc(F)c(-c2c[nH]c3ncnc(N(C)C)c23)c1 +O=C(NCc1ccccc1)Nc1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 +O=S(=O)(Nc1ccc(S(=O)(=O)N(CCC2CC2)c2sc3ccccc3c2Br)cc1)C1CC1 +CC(CC(=O)O)NC(=O)c1ccc2c(c1)CCC1C2CCC2(C)C(c3cncc(F)c3)=CCC12 +Cc1ccccc1C(=Cc1cc(OCc2ccsc2)ccc1C#N)CO +CC(C)(C)CC1NC(C(=O)NCCCCO)C(c2cccc(Cl)c2)C1(C#N)c1ccc(Cl)cc1 +CCCC(=O)Nc1cc(NS(=O)(=O)c2cccs2)cc(-c2csc(=O)[nH]2)c1 +CCCc1c(OC2CCCCC2)c2cc(Cl)ccc2[nH]c1=O +NC1=NC(c2cc(NC(=O)c3nn(C(F)F)cc3Cl)ccc2F)(C(F)F)C2CC2O1 +CCC1CC(n2c(=O)nc(-c3cnn(C)c3)c3oc4ccc(-c5cnn(C)c5)nc4c32)CCO1 +O=C(O)c1ccc2oc(C34CC5CC(CC(C5)C3)C4)cc(=O)c2c1 +COc1ccc(-n2nc3c(NC(=O)CCC(=O)NCCOCCOCCN)nc4ccccc4n3c2=O)cc1 +COc1ccc(C(=O)N2CCOCC2)cc1CSc1nc2cc(F)ccc2n1CC(=O)O +O=C(O)c1cc(C(=O)O)c(C(=O)O)c(C(=O)O)c1C(=O)O +NC(CC(=O)N1CCn2nc(C(F)(F)F)nc2C1Cc1ccc(F)cc1)Cc1cc(F)c(F)cc1F +CN(C)C(=O)C1SC(n2cnc3c(NCC4CC4)nc(Cl)nc32)C(O)C1O +Cc1ccncc1Oc1ccc(S(=O)(=O)Nc2ccc(F)cn2)cc1C#N +NC1CCC(CCOc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)(c2ccc(Cl)cc2)CC1 +CCC(CN1CCC(CNC(=O)c2ccc3cc(Cl)ccc3c2)NC(C2CCNCC2)C1=O)c1ccccc1 +O=C(Nc1cc(C2CCN(C3CCC3)CC2)nn1-c1ccc(C2CC2)cn1)c1cnn2cccnc12 +Cc1c(C=CC(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)cn1C(C)C +COc1cc(OC)cc(OCCCOc2c3ccoc3cc3oc(=O)ccc23)c1 +CCOc1cccc(-c2nccc3c2cc(C(=O)O)n3CCOc2ccc(Cl)cc2)c1 +CCCCCN(CC(O)C(Cc1ccccc1)NC(=O)OC(C)CCC(C)=O)S(=O)(=O)c1ccc2ncsc2c1 +CCc1ccc(CN2C(C(Cc3c[nH]c4ccccc34)NC(=O)C(C)N)=NNC2CCc2ccccc2)cc1 +COc1ccc2ncc(F)c(CC(O)C34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +CN1CN(c2ccccc2)C2(CCN(C(=O)NC3CC4CCC(C3)N4Cc3ccc4cc(F)ccc4c3)CC2)C1=O +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(C=Cc4cc(F)ccc43)CC1)C(O)C2 +CC1=C(C)C(=O)OC(C(C)(O)C2(O)CCC3(O)C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC32C)C1 +CC(C)CC(=O)c1ccc(OCCCCSc2ccncc2)c(Br)c1O +CCNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1CC +Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C4CCNCC4)cc3)ccc2N2CCN(C)CC2)c1Cl +CC(C)CC(C(=O)NCC#N)c1cccc(-c2ccc(C34CCN(CC3)CC4)cc2)c1 +N=C(N)c1ccc(CNC(=O)CN2C(=O)C(NS(=O)(=O)Cc3ccccc3)CSc3cc(CN)ccc32)cc1 +CCNc1nn(C)c2cc(Oc3ccnc4cc(OC)c(OC)cc34)ccc12 +COc1ccc(-c2cn(Cc3ccc(C)cc3)cn2)cc1 +CC(C)(C)c1cc2c(ccc3nc(N)nc(N)c32)[nH]1 +N#Cc1ncc2nc1OCCCCCOc1cc(N)c(Cl)cc1NC(=O)N2 +FC(F)(F)c1cccc(Nc2nc3c(-c4nnc[nH]4)cccc3c3sccc23)c1 +O=C(NC1COCCC1NCC1CC1)c1ccc(C(F)(F)F)cc1C1CC1 +CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3Cc2ccoc2)c2cccc(-c3nn[nH]n3)c2)cc1 +CSCCC(NC(=O)c1ccc(C=Cc2cnccn2)cc1-c1ccccc1C)C(=O)O +CCCCCCCCCCC(O)C1CCC(C2CCC(C(O)CC)O2)O1 +CCCCCCNC(=O)NCCc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +CC(C)CCC(c1ccc(C(F)(F)F)nc1)N1CCC(CC(=O)O)CC1c1ccc(C(F)(F)F)cc1 +Cc1cccc(CN2CCCC(C(=O)N(Cc3cc(Cl)c4c(c3)OCCCO4)CC(C)C)C2)c1 +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(CCc3ccco3)CC2)cc1 +COC1CCN(c2nccc(Nc3cc4c(cn3)nc(C)n4C(C)C)n2)CC1 +CC(C)(O)C(F)CNC(=O)c1cnc(N2CCc3cc(C#N)cnc32)cc1NC1COC1 +CCc1nc2c(C)cc(CC(C)C)nc2n1C1CCc2cc(-c3ccccc3C(=O)O)ccc21 +CC(CC(=O)O)CC(=O)N1CCC2(CC1)CCN(c1ccc(C(=N)N)cc1)C2=O +NC(c1cccc(Cl)c1)C1CCN1C(c1cccc(F)c1)c1cccc(F)c1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2F)n(-c2cc3ccccc3cc2S(C)(=O)=O)n1 +Cn1cc(C2=C(c3c4n(c5ccccc35)CCCCC4)C(=O)NC2=O)c2ccccc21 +CC(C)c1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNCC21 +Cn1c(CN2CC3C(COc4cccc(Cl)c4)C3C2)nc2cnccc21 +O=C(Cc1ccccc1)Nc1cc(-c2c(-c3ccc(F)cc3)nc3n2CCS3)ccn1 +O=C(Nc1ncc(Br)s1)C1C(C(=O)NC2CCCNC2)C2CCC1C21CC1 +Cc1cc(C)n2nc(CCc3nc(-c4cccs4)cn3C)nc2n1 +c1ccc(CCCN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +COc1cc(N2CCN(CCNCC(=O)N3CCCC3C#N)C2=O)cc(OC)c1OC +CCC(CC)OC1C=C(C(=O)NS(=O)(=O)c2ccccc2)CC(N)C1NC(C)=O +COc1cc(Cc2c(-c3ccc(CCN4CCCC4)cc3)sc3cc(O)ccc23)ccc1CN1CCCC1 +COc1ccc(COc2ccc(Cn3c(N)nc4cc(N5CCN(C)CC5=O)ccc43)cc2OC)cn1 +COc1cc2c(N)nc(N3CCN(C(=O)c4cc5ccccc5[nH]4)CC3)nc2c(F)c1OC +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(Cl)c2ccccc12 +O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1)C(=O)c1ccccc12 +N=c1n(CC(=O)c2ccc(Cl)cc2)c2cccc(Cl)c2n1CCCN(C(=O)c1cccc2cccnc12)C1CC1 +CCc1cc2c(N3CCN(C(=O)CCOc4ccccc4)CC3)nc(NC(=O)NCCC(=O)O)nc2s1 +COC(C)c1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCOC(=O)C(=O)CC(=O)C=Cc1cccn1Cc1ccccc1OC +Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3ccc(-c4cnn(C)c4)nc3)c3cc(F)cc(F)c23)no1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCCCCCCCCCOc1ccc(CN3CCCCC3)cc1)C2 +O=C(NCCCCCCS)c1cc(-c2ccccn2)n[nH]1 +O=C(C=CC(=O)N(Cc1ccccc1)c1ccc(I)cc1)N(Cc1ccccc1)c1ccc(I)cc1 +CC1(C)Cc2nc(C3CCOCC3)c3c(c2C(O)C1)C1(CCCC1)OC3c1ccc(C(F)(F)F)cc1 +CN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +CCCc1c(OCCCCCCc2cccc(OCCCCCC(=O)O)c2CCC(=O)O)ccc2c1CCCC2=O +COc1ccc(Cl)cc1C=C1CNC(=O)CN(S(=O)(=O)c2cc(F)c(Cl)cc2OC)C1=O +CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(Cc1ccccc1)NC(=O)OC12CCOC1OCC2 +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(C(=O)N2CCCC2)CN1 +COc1ccc(C(=O)C2CCN(C3CCN(Cc4nc5c(c(=O)[nH]4)COCC5)C3=O)CC2)cc1 +Cc1cccc(CCC(C(C)O)n2cnc3c(N)ncnc32)c1 +O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CN(C2CCC(CNC(=O)C(F)(F)F)CC2)C1 +CC(C)C(O)CN1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +CS(=O)(=O)c1ccc(C(=O)NC2CCC(CCN3CCC(c4cccc5c4CCO5)CC3)CC2)cc1 +CCCCCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(CCCCCO)cc(-c3ccccc3)n2)CC1 +CC12CCC3c4cc(Br)c(O)cc4CCC3C1CCC2=O +CCCCC(NC)C(=O)NC1CCC2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC21 +O=C(CNC(=O)c1ccc(F)cc1)NC(c1ccccc1)c1ccc(Cl)cc1 +CN(C)CC(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)N(O)C=O +CCc1nc(O)c(NCN2C(=O)c3ccccc3C2=O)cc1C +CC1(O)CCC2CC1OOC2(C)CSC(c1ccccc1)(c1ccccc1)c1ccccc1 +CC(C(=O)NO)N1CCC(C)(c2ccc(OCc3ccccc3)cc2)C1=O +CCCCCn1ncc2c(N)c(C(=O)OCC3CC3)c(C)nc21 +Cc1ncoc1-c1nnc(SCCCN2C3CCC2CC(c2ccc(C(F)(F)F)cc2)C3)n1C +CCc1c(N2CCOCC2=O)cccc1S(=O)(=O)NC(CNC(=O)c1ccc(Cl)s1)C(=O)N1CCC(C)CC1 +COc1ccc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C(N)=O)CC3)n2)cc1F +Cn1c(=O)ccc2c(NC(=O)NC3CCC(c4ccccc4F)C3)cccc21 +CCCCCCCNC(=O)Oc1ccc2c(c1)CN(C)C(c1cccs1)N2C +COc1cncc(-c2cccc3c(-c4ccc(C(N)=O)c(NC5CCC(O)CC5)c4)nccc23)c1 +CCOC(=O)C1=C(CN2CCOCC2)NC(c2nc(CC(=O)OC)cs2)=NC1c1ccc(F)cc1Br +Cc1cc(C)cc(-c2ccc(CNc3nc(NC4CCC(N)CC4)nc4c3ncn4C(C)C)cc2)c1 +O=C(O)c1ccc2c(c1)nc(Nc1cccc(O)c1)c1ccsc12 +CC1(C)CCC(C)(C)c2cc(C3(c4ccc(C(=O)O)cc4)OCCO3)ccc21 +CS(=O)(=O)Nc1ccccc1Nc1nc(Nc2ccc(C(=O)OCc3ccccc3)cc2)ncc1F +CC(C)NC(=O)c1ccc(CC2CCN(C3CCN(C(=O)c4cccc5c(F)cc(F)cc45)CC3)CC2)cc1 +CCCOC(=O)c1sc2cc(Oc3ccnc(C(=O)NC)c3)ccc2c1C +Cc1ccc2c(c1)-c1nc3cc(C(F)(F)F)ccc3n1CCO2 +COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cn3ccc4ccccc43)c2cc1OC +CCC(COc1cccc(Cl)c1)OC(=O)NCc1ccccc1 +COc1ccc(-c2cnc(C(=O)N3CCN(c4ccc5ccccc5c4)CC3)nc2-c2ccc(C)cc2)cc1 +Nc1ncc(-c2cc(N3CCOCC3)nc(N3CC(F)C(F)C3)n2)cc1OC(F)F +Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(NCCc6ccccn6)c5)nccc34)cn2)cn1 +CCN(CC)c1ccc(C=NNC(=O)c2ccc3[nH]cnc3c2)c(O)c1 +COc1ccc(C2CC2COc2nc(C)ncc2-c2cc(C)n(C)c(=O)c2)nc1 +CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(S(=O)(=O)c2ccc3[nH]ncc3c2)CC1 +Nc1ccccc1NC(=O)CCCCCNC(=O)c1ccc(F)c(F)c1 +Cc1c(-c2ccc(Cc3ccc(OC(F)(F)F)cc3)cc2)n(O)c2cc(Cl)ccc2c1=O +COc1ncc(-c2nc3c(C)nc(N)nc3n(C(C)C)c2=O)cn1 +N#Cc1ccc(C2OC(CO)C(O)C(O)C2O)cc1Cc1ncc(-c2ccco2)s1 +CN(C(=O)Cc1ccc(CCNS(C)(=O)=O)cc1)C(CN1CCC(O)C1)c1ccccc1 +CCOC(=O)c1c(-c2cc(F)cc(F)c2)c(-c2ccncc2)c(N2CCNCC2)n1C +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)cc1NC(=O)CNC(=O)OC1CC(C)(C)N([O])C(C)(C)C1 +CC(NC(=O)c1ccncc1Cl)C(=O)N1CCCC1B(O)O +Cc1cc(-c2nc3ccc(C4CN(C)CCO4)cc3n2C(C)c2ccccc2)cn(C)c1=O +O=C(NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)C1CC1c1ccccc1 +CC1CN(c2scnc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cc1n[nH]c2ccccc12 +CC1(F)C(O)C(CO)OC1n1ccc(=O)[nH]c1=O +CCCCn1cc(C(C)(C)C)ccc1=NC(=O)c1cc(C(F)(F)F)ccc1ONC(C)(C)C +O=S(=O)(c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)c(Cl)c2)=N1 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1ccc(C)cc1)O2)C(C)=CC(C)(C)N3 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1ccccn1 +COc1cc(F)ccc1N1CCN(CCCNc2c(C(=O)N(C)C)cnc3c(C(N)=O)cccc23)CC1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCCO)c2)[nH]1 +OC(c1ccccn1)C1(c2cccc(OC(F)(F)F)c2)CCC1 +CC(C)NC(=O)NC1CC2(C)OC1(C)C1C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C12 +O=C(NC1CCC(Oc2ccnc3c(Br)cccc23)CC1)c1ccc(C(F)(F)F)c(F)c1 +CC1COCCN1c1cc(C2(S(C)(=O)=O)CCOCC2)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 +CCc1cc2c(=O)n(N)c(SCCCN3CCN(c4ccccc4[N+](=O)[O-])CC3)nc2s1 +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccc(F)cc2)c2cccs2)CC1 +CC(C)(C)OC(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccc(OCc3ccccc3)cc21 +COc1cc(C=C2SC(=O)N(Cc3ccccc3)C2=O)ccc1OCc1ccc(C(=O)O)cc1 +COc1ccc2[nH]nc(C(=O)NCC3CCN(Cc4ccc(C(=O)O)o4)CC3)c2c1 +Cc1ccc(-n2[nH]c3c(cnc4c(Cl)cccc43)c2=O)s1 +Cc1nc2cnccc2n1CCCOC1CCC(c2ccc(F)cc2)O1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1ccc(CN2CCCC2)o1 +c1ccc(Cn2c3c(c4ccccc42)CCN(CCc2ccccn2)C3)cc1 +O=C1N(CCCCCCO)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc2ccccc2c1 +COc1ccc2c(C(=O)C3C(C)(C)C3(C)C)cn(CC3CCOCC3)c2c1 +CCCC(=O)N(Cc1cccnc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +Cc1cnn(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)c1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCCC34CC4)n2)cc1OC(F)F +CCS(=O)(=O)Nc1n[nH]c2c1CN(C1COC(c3cc(F)ccc3F)C(N)C1)C2 +CSCCC(NC(=O)c1ccc(CNc2cccnc2)cc1-c1ccccc1C)C(=O)O +CC(=O)c1ccc(NC(=O)Nc2ccc(OS(N)(=O)=O)cc2)cc1 +CN1CCN(c2nc(N)nc3c2oc2ncc(Cl)cc23)CC1 +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(NC2CCS(=O)(=O)CC2)nc1C1CCC1 +CC(C)C(=O)NC1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +c1ccc(C(c2ccccc2)C2CCC(NCc3ccc4occc4c3)CO2)cc1 +COCCC(=O)NC1CCC(CCN2CCC(c3noc4cc(Cl)ccc34)CC2)CC1 +COc1ccc(N(C)c2ccc(N(C)C)c3ccccc23)cc1 +CC(=O)c1sc(NC(=O)NC2CN(C)CCC2CN2CCCC(Cc3ccc(F)cc3)C2)nc1C +CC(=O)N1CCc2ccc(N(C(=O)C=Cc3ccccc3)C3CCN(CCC4CCCC4)CC3)cc21 +O=C1C(Sc2nnc[nH]2)=CC(=NS(=O)(=O)c2cccs2)c2ccccc21 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1cc(F)c(OCC(F)(F)F)cc1F +CCCCc1cc2c(=O)cc(C)[nH]c2cc1OCCOc1ccccc1 +CCC(NC(Cc1ccccc1)C(=O)Nc1cc(-c2ccncc2)c[nH]c1=O)c1ccccn1 +O=C(CCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1)NC1CCCCC1 +O=C1CC(COc2nc(-c3ccc4c(c3)OCO4)cc3ncccc23)CN1 +CN(C)S(=O)(=O)c1ccc2oc(NC(Cc3ccc(F)cc3)c3ccccn3)nc2c1 +COc1ccc(CN2CC3CN(C(=O)CC(N)Cc4cc(F)c(F)cc4F)CCN3C2=O)cc1 +CCc1ccc(-c2ccc(C(=O)NCC(=O)NC3CNCc4ccccc43)cc2)cc1 +CC(C)=CN1Cc2c(F)ccc3[nH]c(=S)n(c23)CC1C +N#Cc1cc(Cl)cc(Oc2cc(F)c(Cl)c(OCc3n[nH]c4ncccc34)c2)c1 +O=C(OC1CC2COCC(C1)N2)c1cn(-c2nccs2)c2ccccc12 +CC(=O)OC1CCC2(C)C(=CCC3C2CCC2(C)C(C(=O)ON=C(C)N)CCC32)C1 +CNC(C)C(=O)NC1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)C1C +CCSC(=S)SCC(=O)c1ccc(-c2ccc(CNc3cnc4ccccc4c3)cn2)s1 +COCCN(c1c(OC)nn2c(-c3c(OC)cc(COC)cc3OC)csc12)C1CCCCC1 +c1cnc2[nH]cc(-c3ccnc(NC4CCCCC4)c3)c2c1 +O=C(CCCc1ccccc1)Nc1nc2ccsc2c(=O)s1 +NC1=NC(c2cccc(Oc3ccccc3)c2)N(c2cccc(Cl)c2)C(N)=N1 +COc1cccc2c1ccc1nc3ccc(O)c(C(=O)NCCN(C)C)c3nc12 +COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(C(F)(F)F)c(Oc2cccc(C)c2C#N)n1 +CSC(=O)c1ccc(-c2cnc(C(=O)CCCCCCc3ccccc3)o2)nc1 +FC(F)(F)c1cccc(-c2noc(-c3cc(-c4ccccc4)c(C(F)(F)F)s3)n2)c1 +Oc1nc(-c2ccccc2)cn1C1CCN(Cc2ccccc2)CC1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4c(F)cccc4Cl)ncc23)ccn1 +CCc1ccc(-c2cc(O)c3c(c2)OC(C)(C)C2CC=C(C)CC32)cc1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3cc4ccsc4s3)CC2)nc1 +CCOc1ccc(S(=O)(=O)Nc2ccccc2COC)cc1N1CCNCC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CC(C)O)ncc3Cl)C2)cc1 +O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCNC2)c1O)Nc1cccc2c1OC(F)(F)O2 +O=C1NC(=O)c2ccc(Nc3ccc4c(c3)OCO4)cc2C1=CNc1ccc(CN2CCCCC2)cc1 +CC(c1ccc(-c2ccc(=O)[nH]c2)cc1)N1CCC(CC(C)(C)C#N)(c2ccc(F)cc2)OC1=O +CCCCCCCCOc1ccc(-c2noc(C3CCCN3C(=N)N)n2)cc1C(F)(F)F +COc1cc(F)ccc1-c1ccc(C(CC(=O)O)NC(=O)C2(C)CCCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)cc1 +Cc1cc(C)c(Nc2nc(Nc3ccc(C#N)cc3)ncc2Br)c(C)c1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)Nc1cnn(C2CCOCC2)c1 +COc1cccc(-c2[nH]c3ccc(C)cc3c2CCC(=O)N2CCN(c3ccccc3OC)CC2)c1 +Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(C(=N)NO[Si](C)(C)C(C)(C)C)s1 +COC(=O)c1cccc(-n2c(=O)n(Cc3ccccc3)c(=O)c3ccccc32)c1 +COc1cc(Cl)ccc1N1C(=O)COc2cc(S(=O)(=O)Nc3nccs3)ccc21 +COc1cc(-c2ccc3ncnc(Nc4ccc(F)c(O)c4F)c3c2)ccc1O +O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2Br)cc1)c1ccncc1F +CCCCC(NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CN1CCN(c2cncc(-c3c[nH]c4ccc(-c5nnc(N)s5)cc34)n2)CC1=O +CCNC(=O)c1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1Cl +COc1cc(OCc2cccc(OCc3ccccc3)c2)c2cc(-c3cn4nc(Br)sc4n3)oc2c1 +c1ccc2c(c1)ccn2CCCCN1CCN(C2CCCCC2)CC1 +COC(=O)CSc1nnc(Cc2c(NCCC(=O)O)sc3c2CCCC3)n1NC(=O)c1ccccc1 +Cc1occc1-c1ccc(CC(C#N)NC(=O)C2NC3CCC2C3)c(F)c1 +NC(CC(=O)N1CCCC1CN(C1CC1)S(=O)(=O)C(F)(F)F)Cc1cc(F)c(F)cc1F +CCOC(=O)c1ccc(CCCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 +CN1c2ccc(-c3cnc(N)c(F)c3N3CCC4(CC3)CNC(=O)O4)cc2CS1(=O)=O +O=C(Nc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccccc1)OCc1ccccc1 +O=C(O)CC1CCc2cc(OCCCOc3ccc(-n4cncn4)cc3)ccc21 +CNc1nc(NC(=O)c2cccc(I)c2)c2ncn(C3OCC(O)C3O)c2n1 +Nc1nc(OCCC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(=NOCC(N)=O)C5)cn3)n2)s1 +Cc1noc(-c2cnc(C3=CCN(C(=O)Nc4ccc(C(F)(F)F)cc4)CC3)c(Cl)c2)n1 +COc1ccc(C2=Nc3c(C(C)(C)C)nn(CCO)c3C(=O)NC2)cc1-c1cnn(C)c1 +CC(C)NC(=O)Oc1cc(-c2ccnc3c(C(=O)c4cccs4)cnn23)ccc1F +CC(CCc1ccc(-c2ccc(N3CCN(S(C)(=O)=O)CC3)cc2)cc1)(C(=O)NO)S(C)(=O)=O +NC(Cc1cc2ccccc2[nH]1)C(=O)N1Cc2ccccc2CC1C(=O)O +COC(=O)CCCC(=O)Oc1ccc2c(c1)c1cc3c(C(=O)NCCN(C)C)nccc3c(C)c1n2C +c1cncc(Cn2ncc3cc(Nc4ncnn5ccc(COCC6CNCCO6)c45)ccc32)c1 +O=C(NO)c1cnc(N2CC3CN(Cc4cc(Cl)cc(Cl)c4)CC3C2)nc1 +CN1Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4(N)CCOCC4)cc3)cc2C1=O +COc1ccc(Nc2nc3ccc(N4CCN(C(=O)N(C)C)CC4)cn3c2-c2nc(C)nc(N)n2)cn1 +O=C(NCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3CO)n[nH]2)c1 +CCOc1ccc(CC(NC(=O)c2ccccn2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)c(Cl)c2)cc1 +CC1CNC(C2CC2)C(=O)N(C)C(C)C(=O)NC(Cc2ccc(F)cc2)C(=O)NCCCc2ccccc2O1 +CN1c2cc3c(cc2N=C(c2ccc(C(=O)O)cc2)c2ccc4ccccc4c21)C(C)(C)CCC3(C)C +CCCCCCCCC=CCCCCCCCC(=O)NCCC(=O)P(=O)(O)O +Cc1c(-c2nnc(C3(c4ccc(Cl)cc4)CC3)s2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +CC(C)(C)OC(=O)CC1CC(c2ccc(O)c(F)c2)=NO1 +CC(C)(C#N)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +Cc1n[nH]c(=O)c2c1c1cc(Br)ccc1n2Cc1cccc(C#N)c1 +CCN(C(=O)c1ccc(CNc2nc(NCc3ccccc3)nc(N3CCc4ccccc4C3)n2)cc1)c1cccc(C)c1 +COCC1CCCN1C(=O)CC(C)(C)C(N)C(=O)N1CCCC1C#N +CCn1cc(-c2ccccc2)nc1CCc1nc2cc(C)cc(C)n2n1 +Cn1c(C#N)ccc1-c1ccc(C(=O)c2cccs2)cc1 +CCCc1cc2c(=O)c(-c3ccccn3)coc2cc1OC +Cc1cc(N2CCN(S(C)(=O)=O)C(CC(=O)NCc3ccc4c(c3)OCO4)C2)nc(-n2ccnc2)n1 +O=C(Nc1nc2ccccc2s1)c1ccc(-c2ncc(CC(O)CO)cc2F)cc1 +N#Cc1cnc2c(Nc3ccc(F)c(C4(CF)CC(C(F)(F)F)OC(N)=N4)c3)ncc(F)c2c1 +COc1c(COc2ccc(NS(C)(=O)=O)cc2)cc(N2CCC(=O)NC2=O)cc1C(C)(C)C +CCN(CC)Cc1cc2c(N)nc(-c3ccco3)nc2s1 +CC#CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CC(=O)c1ccccc1-c1ccccc1)c(=O)n2C +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2cc(CO)ccc2c1 +O=[N+]([O-])c1cnc(NC2CCC(O)CC2)nc1Nc1ccccc1 +Clc1ncc(C2CC3CCC2N3)cc1-c1cccc(Br)c1 +Fc1ccccc1CNc1nnc(-c2c[nH]c3ncccc23)o1 +CCNC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 +CC(C)CNC(=O)c1ccc(-c2ccc(C#CC(C)(C)O)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +COc1ccc(N(CCN)C(=O)Nc2ccc(-c3ncnc4[nH]cc(C)c34)cc2)cc1 +Cc1c(C)c(C(CCCCCC(=O)O)c2ccc(F)cc2)c(O)c(C)c1C=O +CS(=O)(=O)Nc1cc(C(O)CNC2CCN(c3ccc(C=C4N=C(N)NC4=O)cc3)CC2)ccc1O +COc1cc(C(=O)c2c[nH]c(-c3ccc(Br)cc3)n2)cc(OC)c1OC +COc1ccccc1C(=O)NCC1CCCN(C2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)C1 +NC(CC(=O)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1)C(=O)N1Cc2ccc(F)cc2C1 +O=C1CCC(=C2CC3C4CC(O)C(C4)C3C2)CC1 +O=C(c1ccco1)N1CCN(c2ccc(=O)n(CCCCCN3CCN(c4ccccc4Cl)CC3)n2)CC1 +Cn1c(-c2ccccc2O)nnc1C1(c2ccc(Cl)cc2)CCC1 +Oc1cc(NCCCNCc2cc(Cl)ccc2Cl)nc2ccccc12 +O=C(C=Cc1cccc2cccnc12)Nc1ccccc1N1CCOCC1 +CC1CCCN(c2c(C#N)c(C(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)C1 +CNc1nc(Nc2ccc(C(=O)NC3CCC(F)(F)CC3)cc2OC)ncc1C(F)(F)F +CC(C)N(Cc1ccnn1C)C(=O)Cc1c(-c2ccccc2)[nH]c2ccccc12 +CCCCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2c1)c1ccccc1 +COc1ccc(-c2nc(SC)nc(NCCCCNc3ccnc4cc(Cl)ccc34)c2C#N)cc1OC +Cc1cccc(Br)c1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O +CCC(OC)(c1cccc(OCc2ccc3c(-c4ccccc4)c4c(cc3c2)C(=O)OC4)c1)c1nccs1 +Brc1cnc(NC2CCc3ccccc32)nc1Nc1cc(C2CC2)[nH]n1 +CC(c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2F)OC1=O +Cc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4Br)CC3)n2)ccc1F +O=C(Nc1ccc(-c2nc3cc(NC(=O)C4CCC4)ccc3[nH]2)cc1)c1ccccc1Cl +CC(C)(C)NC(=O)C1CN(Cc2ccccc2S)CCN1CC(O)CC(Cc1ccccc1)C(=O)NC1c2ccccc2CC1O +CN(C)c1nc2ccc(C(O)(c3ccncc3)c3cncn3C)cc2c(Cl)c1-c1ccccc1 +Cc1ccc(C(=O)NC2CC2)cc1Nc1nnc(C)c2c1cnn2-c1ccc(F)cc1 +COc1ccc(C(F)(F)F)cc1N1CCOc2cc(S(=O)(=O)Nc3nccs3)ccc21 +COc1cc(Cl)ccc1-c1ccnc2cc(S(=O)(=O)Nc3nccs3)ccc12 +OC12CCC(c3nnc4c(Oc5ccccc5F)cccn34)(CC1)C2 +CC(Oc1ccc(Cl)cc1)C(=O)Nc1cc(C(F)(F)F)ccc1-n1cncn1 +CC(Cc1ccc(Oc2nonc2S(=O)(=O)c2ccccc2)cc1)NCC(O)c1cc(O)cc(O)c1 +CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2cccc(NC(=O)CCCN)c2)ncc1Cl +COc1ccc(NC2=C(c3ccccc3)C(=O)N(C)C2=O)cc1 +CC1CN(c2cccc(NS(=O)(=O)c3ccc4ccccc4c3)c2)CC(C)N1 +CC(=NOc1ccccc1)c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 +CN1C(=O)C(NC(=O)c2cc3ccc(Cl)cc3[nH]2)Cc2ccccc21 +O=C1CN(Cc2ccc(-c3cccc(CN4CCCCC4)n3)cc2)C(=O)N1C1CCC1 +CCOC(=O)C1=C(CN2CCOCC2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1F +NCCCCC(NC(=O)NC(CC1CCCCC1)C(=O)NC1CC2CCC1C2)C(=O)O +CC(Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NCC(O)c1cccc(OCc2ccccc2)c1 +Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)C3CCCC3)CC2)c1 +CCC1=C(C(=O)CCC2CCCCCC2)C(c2ccc(O)c(Cl)c2)NC(=O)N1 +NCCCCN(CC1CN(Cc2ccccc2)CCN1)C1CCCc2cccnc21 +CCCC(CC)Nc1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +COc1cc2ncnc(Oc3ccc4c(C(N)=O)cccc4c3)c2cc1OC +COc1cc(C)cc2cc(-c3c(CNCCO)c(CN4CCNCC4)n4ncnc(N)c34)sc12 +CCCCNC(=O)N(CCCC(C)Nc1cc(OC)cc2cccnc12)Cc1ccc(OC)c(OC)c1 +Nc1nccc(-c2cc(N3CC(O)C(O)C3)ccc2O)n1 +COc1cccc(CN(C(=O)C2=C(c3ccc(CCCOc4c(F)ccc(F)c4Cl)cc3)CC3CNCC2N3)C2CC2)c1C +COC1C(O)C(O)C(Oc2ccc(CCNC(C)=O)c(-c3ccccc3SC)c2)OC1(C)C +O=C1C(=O)N(CC(CO)NCCCCCCNc2ccnc3cc(Cl)ccc23)c2ccc(Cl)cc21 +CC1(O)COc2ccc(C#CC3(O)CCCC3)cc2-c2nc(C(N)=O)sc21 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C)nc2-c2ccccc2)n1 +O=C(c1cccc(Cl)c1Cl)N1CCc2c(ncnc2-c2nccs2)C1 +O=C(N1CCOCC1)N1CCN(c2ccc(I)cc2)CC1 +CC(O)C(CO)Nc1nc(SCc2cccc(F)c2F)nc2nc(N)sc12 +Cn1cnc(S(=O)(=O)N2CC3C(C2)C3(CNC(=O)c2ccc(Cl)cc2Cl)CC2CC2)c1 +N=c1sc(-c2cc(F)ccc2F)nn1-c1c(Cl)cc(C(F)(F)F)cc1Cl +Cc1cc(C=CC#N)cc(C)c1Oc1ccc([N+](=O)[O-])c(Nc2ccc(C#N)cc2)n1 +CCOc1ccc2cc(-c3nn(C4CCOC4)c(N)c3C(N)=O)cnc2c1 +Cc1ccc(C)c(N2CN(Cc3cccnc3)CN=C2S)c1 +CC(C)Oc1ccc(Nc2ncc(NCC3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F +CCN(CC)CC1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +COc1ccc(C=CC(=O)CC2OC(COC(C)=O)C(OC(C)=O)C(OC(C)=O)C2OC(C)=O)cc1OCc1ccccc1 +CCOC(=O)CCc1ccccc1OP(=O)(NC(C)C(=O)OCC)OCC1OCC(n2cnc3c(NC4CC4)ncnc32)O1 +NC(N)=NC(=O)c1ccc2c(c1)Nc1ccccc1O2 +COc1cc2c(cc1NC=O)CCC1C2CCC2(C)C(=O)CCC12 +Cc1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)N4C(C)CCC4C)CC3)c2)c1 +CC(O)C1NCCOc2ccccc2CCCNC(=O)C(Cc2ccccc2)NC(=O)C(C)N(C)C1=O +O=C(CCn1c2c(c(=O)[nH]c1=O)CSCC2)NCC(=O)c1ccc(-c2ccccc2)cc1 +CCCCCCCCNC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)COc3ccc(O)cc3)cc2)cc1 +c1ccc(CCCN2CCN(CCSC(c3ccccc3)c3ccccc3)CC2)cc1 +COc1cc(Br)c([S+]([O-])Cc2ccc(Cl)c(OC3CCN(C)C3)c2)cc1OC +CCC(C)C1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)N1CCOCC1)c1cc(C)cnc1C +N#CCC1(n2cc(C(N)=O)c(Nc3ccc([S+]([O-])C(F)F)cc3)n2)CCC(Nc2cccc(O)c2)CC1 +CN(C)c1ccc(C=CC(=O)C=Cc2cccc(F)c2)cc1 +CC(C)(C(=O)O)C(c1ccc(Nc2ccc3ccccc3c2)cc1)n1ccnc1 +COc1cccc2cc3n(c12)CCN(CCCCNC(=O)C1=Cc2ccccc2CN1)C3 +Cn1cnc(NCc2ccncc2)c1C(=O)Nc1cccc(OC(F)(F)F)c1 +O=C(NCC(NS(=O)(=O)c1cccc(N2CCOCC2=O)c1Cl)C(=O)N1CCC(O)CC1)c1ccc(Cl)s1 +CC(C)CS(=O)(=O)CC(NC(=O)c1cc(-c2ccccc2)cs1)C(=O)NCC#N +CC(=O)c1ccc(-c2cc(-c3cc4c([nH]3)CCNC4=O)ccn2)cc1 +CC1(C)CC(c2cc(F)ccc2F)N(c2ccn3ncc(NC(=O)c4cnccn4)c3n2)C1 +CCN(CC)Cc1cnc2c(C#N)c(-c3cc(OC)c(OC)c(OC)c3)cc(-c3ccc(F)cc3F)n12 +CC(=O)c1cc(F)c(Cl)cc1NCC(=O)Nc1ccccc1C(=O)O +O=C(Nc1cc(F)ccc1-c1nc2ccccc2[nH]c1=O)c1cccs1 +Cn1c(-c2ccccc2)cc2c3no[n+]([O-])c3ccc21 +Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CC2)NCNC3=O)nc1 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+CCCC(CCC)N1CCn2c(=O)n(-c3ccccc3OC)c3nc(C)cc1c32 +CC(C)Oc1ccc(-c2ccccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)cc1 +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)N(CC)CC)c3ccc(OC(F)(F)F)cc3)CC2)c(F)c1 +O=C(O)c1cc(=O)c2ccc(OCCCN3CCC(C(O)(c4ccccc4)c4ccccc4)CC3)cc2o1 +NC(=O)c1cccc2c(NC3CNCC(c4ccccc4)C3)ncnc12 +CCC(CC)(NC(=O)c1cc(OCC2(C)COC2)c(C2CC2)cn1)C(=O)NCC(F)CCl +O=C1CSC(=NNc2nncc3ccccc23)N1c1ccc(Cl)cc1 +COc1cccc(-c2ccc3c(c2)Nc2ccc(CCC(=O)N(C)C)cc2NC3=O)c1 +Nc1cc[n+](Cc2ccc3c(c2)-c2cc(C[n+]4ccc(N)c5ccccc54)ccc2C3)c2ccccc12 +O=C(Nc1nc(-c2ccncc2)cs1)N1CCN(CC2CCCO2)CC1 +Cn1cnc2c(NCCNCCO)nc3sc(-c4ccc(F)cc4)nc3c21 +CC(C)c1ccccc1SC1=C(O)OC(CCCCC(=O)N2CCSCC2)(c2ccccc2)CC1=O +CC(=O)C1=CCC2C3(C)CCC4C(C)(C)CCCC4(C(=O)O)C3CC(=O)C2(C)C1C=O +COc1cnc(-n2cnc(C)n2)c2[nH]cc(C(=O)C(=O)NC3C4CN(C(=O)c5ccccc5)CC43)c12 +O=C(Nc1ccc(OC2CCN(C(=O)C3CCCCC3)CC2)cc1)N1Cc2ccccc2C1 +COC1CC(C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +COc1ccc(-c2cc(-c3ccc(-n4cncn4)cc3)cnc2N)cn1 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+O=C(O)Cc1cn(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccncc1 +CCOC(=O)c1ncn2c1c(CO)c(-c1ccccc1)c1ccccc12 +CN=C(N)NCCCC(NS(=O)(=O)c1cccc2c(N(C)C)cccc12)C(=O)N1CCCCC1 +COc1cccc(N2CCN(C(=O)C3CN(S(=O)(=O)c4ccc(OC)c5ccccc45)c4ccccc43)CC2)c1 +O=c1[nH]c(Cc2ccccc2)nc2c1cnn2C1CCOCC1 +CC(=O)n1c(=O)n(Cc2c(F)cccc2F)c2cc(Cl)ccc21 +CN1CCN(CCCOc2ccc(-n3c(-c4ccccn4)nc4cc(F)ccc43)cc2)CC1 +COc1cc(-c2cc(NC(C)c3cccc(OCC(N)=O)c3)nc(C)n2)ccc1C +CC(C)c1ccccc1Nc1nc(SCc2cccs2)n[nH]1 +COc1ccc2cc(-c3cccc(CBr)c3)cc(CCNC(C)=O)c2c1 +CN(C)C(=O)C(CC1CC1)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 +COC(=O)c1cccc(CN2CC3(CCN(CCc4c[nH]c5ccc(F)cc45)CC3)OC2=O)c1 +CC(C)(C)CCC1(C)CN(C2CCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O +Cc1ccc(NC(=O)CN2C(=O)SC(=Cc3cc(Cl)c(OCC(=O)O)c(Cl)c3)C2=O)cc1 +Nc1nc(C#CC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CCC(CO)Nc1ccc2ncc(-c3cccc(C(=O)O)c3)n2n1 +N#Cc1c2ccccc2cn1CCCNC12CC3CC(CC(C3)C1)C2 +O=C(NC1CCc2c(Cl)cc(Cl)cc21)C1COc2ncccc21 +CNC(=O)C(C)C(C)(C)NC(=O)c1cc(OCC2CC2)c(Cl)cn1 +CCCCOc1ccc(C(CC)NC(=O)Oc2ccccc2F)cc1 +COC1(C#CC(O)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CN2CCC1CC2 +COCCOCc1csc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c1Cl +O=C(O)c1ccc(OC2CCN(C(=O)NCc3ccc(Cl)cc3Cl)CC2)cc1 +CSc1nn(-c2ccccc2)c2cc(NC(=O)C3(F)CCNCC3)ccc12 +CC1(C)C(=O)C(C#N)=CC2(C)C3=CC(=O)C(C#N)=CC3(C#Cc3ncc[nH]3)CCC12 +CC1(C)C(=O)Nc2cc3nccc(Oc4ccc(NC(=O)Nc5ccc(F)c(C(F)(F)F)c5)cc4Cl)c3cc21 +CS(=O)(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1ccc(N2CCCC(N)C2)nc1 +C#CCN(C)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)cc1 +Cc1cc(C(C)(C)C)ccc1Nc1nc2ccc(C#N)cc2[nH]1 +O=C(Nc1cccc2c(S(=O)(=O)c3cccc4ccccc34)n[nH]c12)C1CCNCC1 +CCOc1cc(N=S2(=O)CCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NCC(F)(F)F)c12 +CC1(N2CCOCC2)CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +CC#CC1CN(S(=O)(=O)c2ccc(N)nc2)CCN1c1ccc(S(=N)(=O)C(F)(F)F)cc1 +Clc1ccc(-n2cc(COc3ccnc4ccccc34)nn2)cc1 +Cc1cnc(-c2nnc3n2CC(C)N(Cc2cccc(C(F)(F)F)c2Cl)C3=O)cn1 +CN1CCN(c2ccc(-c3ccc4[nH]c5nccc(N6CCC(Cc7ccccc7)CC6)c5c4c3)cc2)CC1 +CCCCCN1CCCc2cc(Oc3ccc(C(N)=O)cn3)ccc2C1 +O=S(=O)(c1ccc(F)cc1)n1cc(C2=CCCNC2)c2ccccc21 +CCCN(c1nc(-c2ccc(Cl)cc2OC)n(C)n1)C(C(C)C)C(C)C +CC(C)(CO)n1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1 +Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(F)cc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 +CCC(C)(C)NC(=O)Nc1nc2ccc(C(=O)Nc3c(C)cccc3Cl)cc2s1 +CCOc1ccc2c(c1)OC(N)=C(C#N)C2c1cc(Br)c(OC)c(OC)c1 +CC1(C)OC(=O)N(C2CCC(NC(=O)c3cn4ccccc4n3)CC2)C1c1ccccc1 +Cc1ccc2cc(-c3n[nH]c4ccc(C)cc34)[nH]c2c1 +NC1CCCN(c2cncc(-c3cc4c(-c5ccccc5F)n[nH]c4cn3)n2)C1 +COc1ncc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOCC1 +CCOCCC1(Oc2ccc(Oc3ccc(-c4cn[nH]c4)cc3)cc2)C(=O)NC(=O)C(N)C1=O +CC(=O)NC1C(NC(=N)NC(=O)Cn2cc(-c3ccc(F)cc3)nn2)C=C(C(=O)O)OC1C(O)C(O)CO +CCON=Cc1cccc2c1CCC1C2c2cc(O)c(Cl)cc2CCN1C +CC(C)(C)c1cc(NC(=O)C2CCCCN2C(=O)N2CCCCC2)no1 +O=C(Cc1cccc(F)c1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3cccc(F)c3)s2)s1 +CC(Cc1nc2cc(C=CC(=O)NO)ccc2n1CCCO)c1ccccc1 +O=C(Nc1ccc(Br)cc1)NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCN2CCOCC2)CCCC1 +O=C1NCN(c2ccccc2)C12CCN(C1CCc3ccccc3C1)CC2 +CCC1=C(c2ccc3c(c2)OCO3)C(=O)OC1(O)c1ccc(OC)cc1 +CCOC(=O)Nc1cccc(N2CCN(CCCCNC(=O)c3ccc4ccccc4c3)CC2)c1 +CC(=O)c1c2c(n3cccc(F)c13)C(=O)c1ncccc1C2=O +C[N+]12CCC(OC(=O)Nc3ncsc3-c3ccc(F)cc3)(CC1)CC2 +COc1cc2nc(N3CCC(OCC(C)OC)CC3)nc(N)c2cc1OC +CCOC(=O)CC(=O)Nc1cccnc1C(=O)Nc1nccs1 +O=C(NC1CC=C(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1)C1CCOCC1 +O=S1NC(c2ccc(S(=O)(=O)N(CCCCC(F)(F)F)c3sc4ccccc4c3Cl)cc2)=NO1 +CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(OC)cc1 +COC(=O)C(C)NP(=O)(O)OCC1CCC(n2cnc3c(N)ncnc32)C1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(C#Cc3cnccc3O)CCC2C)c1 +O=C(O)C1CC1c1ccc(NCc2ccc(-c3ccccc3)cc2)cc1 +Cc1nnc(CC23CC(F)(F)C(C)C(C=Cc4ccc(-c5ccccc5Cl)cn4)C2C(C)OC3=O)o1 +N#Cc1cnc2[nH]cc(C(=O)c3cccc(NS(=O)(=O)c4cccc(F)c4)c3F)c2c1 +CCCn1c(=O)n(CC(C)C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5)CC4)cc3)cc21 +NS(=O)(=O)Oc1ccc(C(c2ccc(OS(N)(=O)=O)c(Br)c2)n2cncn2)cc1Br +COc1cc(-c2c(COC(=O)NC(C)C)c(COC(=O)NC(C)C)c3n2Cc2ccccc2C3)cc(OC)c1OC +O=C(NO)c1cc2ccc(NS(=O)(=O)c3cccc4ccccc34)cc2s1 +CC(CCc1ccc(O)cc1)NC(=O)Cc1c(-c2ccccc2)[nH]c2c(OCCN3CCCCC3)cccc12 +Cc1cccc(C)c1C(=O)NC(Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)C(=O)O +COCCOCCN1C(=O)C(c2ccc(Cl)cc2)N(C(C)c2ccc(Cl)cc2N)C(=O)c2cc(I)ccc21 +O=C(O)CCCOc1ccc(-c2cc(Oc3cccc(F)c3)ccc2Cl)cc1 +CC(=O)N1CCN(c2cccc(-c3cc(-c4ccnn4CC(F)(F)F)c4c(N)ncnn34)c2)CC1 +CCc1cc(C(=O)NC(Cc2cccc(Cl)c2)C(=O)NCC#N)n(C)n1 +Nc1nc(Cl)c(C#Cc2cccnc2)c(NC2CC(CO)C(O)C2O)n1 +O=C(c1ccc(F)cc1)N1CC2CCN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1 +COC1CCC2(CC1)Cc1ccc(Br)cc1C21NC(=S)N(C2CCN(C)CC2)C1=O +Cn1ncc2c1CCCN2c1cnc2[nH]cc(C(=O)NC(C)(C)C)c2n1 +COc1cccc2c1CCCC2NC(=O)CC1C(=O)NC=CN1S(=O)(=O)c1ccc(C)cc1 +COc1ccc(OCCCON2C(N)=NC(N)=NC23CCOCC3)cc1 +COc1ncc2c(n1)nc(Nc1c(C)cccc1Cl)c1cncn12 +CCOc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2ccc(OC)cc2)CC1 +CN(C)CCc1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 +CCOc1ccc(-c2cccn3nc(NC(=O)C4CC4)nc23)cc1 +O=[N+]([O-])c1ccc(-c2cn(Cc3ccccc3)c3c2CNCC3)cc1 +CCCC(NC(=O)c1ncco1)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 +Cc1cc(-c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4n3C)cc2)ccn1 +CC(C)c1ccc2occ(C=C3C(=O)N(c4c(Cl)cccc4Cl)c4ccccc43)c(=O)c2c1 +O=C(O)CN1CCN(c2cc(-c3cnc4ccc(N5CCCC5c5cccc(F)c5)nn34)ccn2)CC1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc(C(F)(F)F)cn3)n[nH]c2C1(C)C +CC(=O)NCCCC1OCC(Oc2ccc(OC3CCCC3)cc2)CO1 +CCNC(=O)c1ccc(-c2cc3nnn(C4CCN(c5ncc(CC)cn5)CC4)c3cn2)c(F)c1 +CC1CCCN(c2ncnc3[nH]cc(-c4cccc(C(=O)O)c4)c23)C1 +NC(CS)C(=O)Nc1ccc(NC(=O)Cc2cccc3ccccc23)c(C(=O)c2ccccc2)c1 +COC(=O)c1ccc(NC(=O)CCN2CCC(Cc3c[nH]cn3)CC2)cc1 +O=C(Cn1ncc2c(=O)oc3ccccc3c21)Nc1ccc(F)cc1 +OC(CNCc1ccccc1)Cn1c2ccc(Br)cc2c2cc(Br)ccc21 +Cc1cc(C)c2cc1C(=O)NCCCNC(=O)CCSc1cc-2nc(N)n1 +Cc1nc(-c2ccccn2)nc(NCC(NC(=O)CCN2CCNCC2)c2ccccc2)c1Cl +COc1cc(CCN2CCC(O)(c3ccc(Cl)cc3)CC2)ccc1OCCSSCCN +Cc1cccc(-n2cnc3cc(C(=O)N4CCCC4)ccc32)c1 +CC(C)c1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1 +Fc1ccc(-n2ncc3c(-n4ccnc4)ccnc32)cc1 +COCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3cc(C)ccc3C(F)(F)F)cc2[nH]1 +CC[N+]1(CC2=CCCCCCC2)CCC(NC(=O)C2c3cc(Br)ccc3Oc3ccc(Br)cc32)CC1 +COc1cc2c(C)[nH]c(=O)c(Cc3ccnc4ccccc34)c2cc1OC +O=C(Cc1cn2cc(Cl)ccc2n1)N1CCC2(CC1)CN(Cc1ccc(-n3nccn3)cc1)C2 +O=C1Nc2c(Br)cccc2C1=C1Nc2ccc(C=NO)cc2C1=O +CCc1ncc(Cc2ccc3nc(C)ccc3c2)c2cc(OC)c(OC)cc12 +O=C1NC(Nc2ccc(O)cc2)=NC1=Cc1ccc2c(c1)OCO2 +CC(C)c1csc(NC(=O)C(CC2CCOCC2)c2ccc(S(=O)(=O)C3CC3)cc2)n1 +CN1CCC(c2cc3c(-c4nc(NCC5CCNCC5)ccc4Cl)ccnc3[nH]2)CC1 +c1coc(C2CNC(=Nc3ccc4c(c3)CCCC4)N2)c1 +CC(NC(CCCCCCCCCN)C(=O)NC(CCCN=C(N)N)C(=O)Nc1ccccc1)C(=O)O +CCCCCCC(=CCCCCCCCC(=O)O)[N+](=O)[O-] +O=C1NC(=S)SC1=Cc1csc(-c2ccccc2C(F)(F)F)n1 +CC(C)COC(=O)N1CC2CC1CN2C(=O)C1(C(C)C)CCC(NC2CCOCC2F)C1 +COc1ncc(-c2ccc(F)c(C)c2)c(N2CCC(c3[nH]cnc3C)CC2)n1 +NCc1c(N)nc(N2CCC2)nc1-c1ccc(Cl)cc1Cl +Cc1cc(S(=O)(=O)N2CC(F)(F)C2)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +CN(C)CC1CCc2cc(-c3ccccc3F)ccc2C1(O)c1cccc(O)c1 +Cc1cccc(N2CCN(CC(O)COc3ccc(C(=O)CCc4ccccc4)cc3)CC2)c1C +COc1ccccc1N1CCCN(CCCCNC(=O)c2ccc(-c3ccccc3)s2)CC1 +CCN(C(=O)c1ccccc1OCc1ccccc1)C1CCCC(N)C1 +O=C(Nc1ccc(C(F)(F)F)cc1)N1C2CCC1CC(S(=O)(=O)c1ccncc1)C2 +CC1(c2cc(NC(=O)c3ncc(F)cc3F)ccc2F)CS(=O)(=O)C2(CCC2)C(=N)N1 +CCCCN1C(=O)C2(CCCC2)CC(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccccc1N1CCN(CCOc2ccc3nc[nH]c3c2)CC1 +COc1c(N2CCOCC2)cccc1N1CCN(Cc2ccc(F)cc2Cl)C(=O)C1=O +CCCc1cc(Cc2cnc(N)nc2N)cc2c1OC(C)C2C +COC1CCC(NC(=O)c2n[nH]cc2NC(=O)c2ccccc2)CC1 +CCC(CN1CCC(CNC(=O)c2ccc3ccccc3c2)NC(CCC2CCCCC2)C1=O)c1ccccc1 +O=C(CCCCCCc1ccccc1)c1nnc(-c2cccs2)s1 +CCCCC(O)c1ccc(NC(=O)N2CCCc3ccc(C=O)nc32)nc1 +Cn1cc(-c2cnc(N3CCOC(Cn4nc(-c5cccc(C#N)c5)ccc4=O)C3)nc2)cn1 +COc1ccc(-c2cccc(C(=O)O)c2)cc1OC1CCCC1 +Cc1cccc(CS(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1 +Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1 +CCOc1ccc(COc2c(OC)cc(C=CC(=O)N3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)cc2OC)cc1 +CC1C2Cc3ccc4c(NCc5ccccc5)ncnc4c3C1(C)CCN2CC1CC1 +CCN(CC)CCCc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +O=C(Nc1n[nH]c2nc(-c3ccc(O)cc3)c(-c3ccccc3)cc12)C1CC1 +N=C(N)c1ccc(CNC(=O)Cn2c(-c3ccccc3)c(Cl)nc(NCCc3ccccc3)c2=O)cc1 +O=C(O)CCC(=O)NC(CC(=O)O)Cc1ccc(-c2cc(Cl)ccc2Cl)cc1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccc2[N+](=O)[O-])c1C +CNS(=O)(=O)N(C)C1CC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +O=C1CN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CCN1Cc1cc2c[nH]ccc-2n1 +CC(O)(C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2)c1cnccn1 +CN1CCN(c2cccc3nc(CN(CC(F)(F)F)C4CCCc5cccnc54)cn23)CC1 +CC(C)NCC(O)COc1ccc(C(C)C)cc1OCC(O)CNC(C)C +CC(C)NC(=O)NC(=O)C1CCCN1C(=O)C(CC1CCCC1)CN(O)C=O +CN(C)Cc1ccc(CSCCNc2cc(N)c([N+](=O)[O-])cc2[N+](=O)[O-])o1 +CCc1ncnc(-c2ccc(C(=O)N3CCC4(CCN(C)CC4)CC3)c(OC)c2)c1C#Cc1ccc(N)nc1 +O=S1(=O)Nc2c(ccc3cccnc23)CN1c1ccccc1 +CC1CN(c2ncc(C#Cc3ccc(F)cc3)cn2)C(=O)OC1(C)C +CCCCCCC1=C(c2ccccc2)C2(Nc3ccc(Cl)cc3)CCCC2C1 +Clc1ccc(-c2c[nH]c(-c3cccnc3)n2)cc1Cl +O=C(Nc1nc2ccc(F)cc2s1)C(Cc1c[nH]cn1)NC(=O)C1OC1C(=O)O +CCC(=O)CCCCCC(NC(=O)C1CCN(C)CC1)c1ncc(-c2cc3ccccc3cn2)[nH]1 +COc1ccc(CNCCCNC(=O)C(C)(C)NS(=O)(=O)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1 +CC(C)CCn1cc2c(nc(NC(=O)NC3CCCCC3)n3nc(-c4ccco4)nc23)n1 +COc1cccc(-c2nc3ccc(N4CCN(C)CC4)nn3c2-c2ccncc2)c1 +CC(C)CC(C(=O)NO)C(=O)NCc1ccc(Cl)cc1 +Cc1ccn(-c2ccc(C(=O)N3CCC(F)(F)C(=CC(=O)NCc4nccs4)c4ccccc43)c(Cl)c2)n1 +CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2cccc(Cl)c2)CC3)n1 +CN(C)CCn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(C)c4)cc2)CC3)cn1 +Cc1nc(NC2CCCC2)sc1-c1nc(Nc2ccc(N3CCN(S(C)(=O)=O)CC3)cn2)ncc1F +CNC(=O)C(=O)CCCCCCC(=O)Nc1nc(-c2ccc(OC)cc2)cs1 +CCNc1cc(C(=O)NC(Cc2ccccc2)C(O)CNCc2cccc(OC)c2)cc(N2CCCCS2(=O)=O)c1 +N#Cc1cnn(C(=O)N2CCN(Cc3ccc(-c4ccccc4)cc3)CC2)c1 +CN(C)CCCOc1ccc(CN2CCC(NC(=O)c3ccc(Br)cc3)C2)cc1 +CCOc1ccc(-c2n[se]nc2-c2cc(OC)c(OC)c(OC)c2)cc1 +O=C(NCCN1CCN(C(c2ccccc2)c2ccccc2)CC1)c1ccccc1 +CCCc1ncc(Cc2ccc3cccc(OCc4nnn[nH]4)c3n2)c2cc(OC)c(OC)cc12 +COC(=O)c1cc(Br)cc(NC(=O)C2CC3CC3N2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 +O=C(O)CCNC(=O)c1cc2c(s1)CCN(CCC1CCNCC1)C2=O +CC(C)N1CC(C(=O)N2CCN(C3(CNS(=O)(=O)Cc4ccccc4)CCCCC3)CC2)C(c2ccc(Cl)cc2)C1 +Cc1ccncc1-n1nc(C)c(CC(=O)NCc2ccc(F)cc2Cl)c1C +Cc1cc(Br)cc(C(=O)NO)c1N(C)S(=O)(=O)c1ccc(OCC#CCO)cc1 +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CCn2ncc(C=O)c2C1 +COC1CCC(C)(N2CCC(N3C(=O)Cc4ccc(C)cc43)CC2)CC1 +COc1cc(C=C2SC(=S)N(CC(=O)O)C2=O)ccc1OCc1nc2ccccc2c(=O)n1-c1ccc(C)cc1 +Cn1cncc1C(OCc1ccc(C#N)cc1)c1ccc(C#N)c(-c2ccccc2C=O)c1 +CC(=O)NC(Cc1ccc(OCCCCC2CCNCC2)cc1)C(=O)O +O=C(c1cccs1)c1cnn2c1n[n+]([O-])c1ccc(OCc3ccccc3)cc12 +CC(Oc1c[nH]c(=O)c(-c2nc3ccc(C(=O)NCCN4CCOCC4)cc3[nH]2)c1)c1c(Cl)ccc(F)c1Cl +c1cc2[nH]cc(-c3cncc(C4CC4)n3)c2cc1-c1nnc(NC2COC2)o1 +Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1CCN(C)CC1 +COc1ccc(NC(=O)N(C)c2ccc3[nH]c(-c4n[nH]c5ccccc45)cc3n2)cc1 +CCSc1ccccc1-c1ccc(-c2cnc3[nH]ccc3n2)c(F)c1 +Cc1noc(-c2ccccc2C(=O)N2C3CCC2C(COc2ccccn2)C3)n1 +CS(=O)(=O)c1cc(F)cc(CNC(=O)c2ccc(-c3nc(C4CCOCC4)cnc3N)cc2F)c1 +CC(C)(C)NC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC1CCCN2C(=O)N(Cc3ccccc3)C(=O)CC12 +Nc1c(C=NO)ccc(-c2ccccc2)c1-c1ccccc1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C(C)=O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)cc31)C(=O)NCCC2 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+N=C(N)c1cccc(CC(NS(=O)(=O)c2cccc(NC(=O)CCN)c2)C(=O)N2CCC(CCN)CC2)c1 +COC(=O)C=Cc1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(C)cc1 +CC(C1=C(CCN(C)C)Cc2cc(F)ccc21)c1nccs1 +O=S(=O)(NCC1CCCO1)c1ccc(NC2CC3CCC2C3)cc1C(F)(F)F +O=C(NCc1ccccc1)c1ccc2nc(NC3CCC(O)CC3)c3nccn3c2c1 +COc1ccc(CC2COCCN2C(=O)c2ccccc2-n2nccn2)cc1-c1ncco1 +CCCCOC(=O)N1CCC(c2ccccc2)(c2nccn2Cc2ccccc2)CC1 +CC(C)(C)c1cc(C(=O)N2CCS(=O)(=O)CC2)c(NC(=O)Nc2ccc(Cl)cc2)s1 +CCCSc1nc(NC)c2ncn(C3CC(OP(=O)(O)O)C(COP(=O)(O)O)O3)c2n1 +Cc1cccc(S(=O)(=O)N2CCC(N(Cc3ccc4ccc(C(=N)N)cc4c3)S(C)(=O)=O)CC2)c1 +COc1ccnc(Nc2ccc(Cl)c(OCc3ccccc3C)c2)n1 +N#Cc1c(F)c(F)c(-c2cc(COCC3(c4ccccc4)CCNCC3)cc(C(F)(F)F)c2)c(F)c1F +Cc1cccc(-c2ccc(C(=O)NC(CCCNC(=N)N)C(=O)O)o2)c1 +COCC1CNC(C)CN1CC(=O)N1CC(C)(C)c2ccc(Cc3ccccc3)cc21 +COc1ccc(CC(NC(=O)CNC(=O)CNC(=O)CNC(=O)c2ccc(S(N)(=O)=O)cc2)C(=O)O)cc1 +CCCS(=O)(=O)c1cc(NC(Cc2ccc(-c3c(OC)cccc3OC)cc2)C(=O)O)ncn1 +COc1ccc(C2CC(=O)C3=C(C2)NC(C)=C(C(=O)OC(C)C)C3c2cccc(Cl)c2)cc1OC +CC(C)n1nc(C=Cc2cccc(O)c2)c2c(N)ncnc21 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+O=C(c1cccc(Cc2nnc(O)c3ccccc23)c1)N1CCCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 +COc1cc(Nc2ncc(-c3ccccc3N(C)C(=O)CO)o2)ccc1-c1cnco1 +COc1cc(-c2nc(Nc3ccc(Cl)cc3)c3ccccc3n2)cc(OC)c1OC +CCCCCC1=NN(C(=O)NCC2CCCCC2)CC1c1ccccc1 +NCC(c1ccc(C(F)(F)F)nc1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1 +COc1ccc(S(=O)(=O)c2ccc(F)cc2)c(Cc2c(C)c(CC(=O)O)c3ccncn23)c1 +CCn1nc(-c2cccc(-c3cccc(CC(=O)O)c3)c2)cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O +COc1cc2c(cc1OCCCCCN1CCN(C3=NS(=O)(=O)c4ccccc4N3C(C)C)CC1)N=CC1CCCN1C2=O +COc1cccc2c(CC(C)NCC(O)c3cccc(NS(=O)(=O)c4cccs4)c3)cn(Cc3ccccc3)c12 +CC(CCOCC(O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 +Cc1ccc(C=C2CN(C(=O)c3ccc(OCCN4CCCCC4)cc3)CC(=Cc3ccc(C)cc3)C2=O)cc1 +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2nnc(N)s2)c(F)c1 +CC(O)(c1ccc(C(=O)N(C2CC2)C2CCC(CCC(N)=O)(c3ccc(F)cc3)CC2)cc1)C(F)(F)F +COc1cc(-c2ccc(Cl)c(C)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)c(F)cc21 +COc1ccc(-c2ccc3cnc(Nc4ccc(N5CCN(C)CC5)c(Cl)c4)nn23)cn1 +CN1CCN(CCNC(=O)C2NC(CC(C)(C)C)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)CC1 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+COC(=O)C1C(c2ccc(C)c(C)c2)CC2CCC1N2C +O=[N+]([O-])c1cc2nc(O)c(O)nc2nc1[N+](=O)[O-] +CC(=O)CN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O +Cc1nnc2n1-c1sc(C#CCn3c(=O)c4cc(Cl)ccc4c4ccc(Cl)cc43)cc1C(c1ccccc1Cl)=NC2 +CNC(=O)C(CCOC)NC(=O)C(OCc1ccccc1)C(O)C(O)C(OCc1ccccc1)C(=O)NC1c2ccccc2CC1O +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(c3cccc(C(N)=O)c3)CC2)ncc1Br +CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC1CCCN2C(=O)N(Cc3ccccc3)C(=S)CC12 +Cc1noc(-c2cc3cc(-c4nc(C(=O)NCc5ccncc5)[nH]c4C)ccc3[nH]2)n1 +COc1ccc(Cn2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)cc1 +CC(CCc1ccc(O)cc1)NC(=O)Cc1c(-c2ccccc2)[nH]c2cc(OCCCN3CCCC3)ccc12 +CC1CN(c2cc(-c3n[nH]c4ccc(-c5ccncc5)cc34)ncn2)CC(C)O1 +Oc1cccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccccc4C(C)C)no3)ccc21 +Cc1cncc(NS(=O)(=O)c2ccccc2C(F)(F)F)c1 +COc1ccc2c(c1)CN(C(=O)C(C)C)N=C2Cc1c(Cl)cncc1Cl +Cc1nc2ccc(S(=O)(=O)Nc3ccc(-c4nc5cccnc5s4)cc3)cc2s1 +O=c1[nH]c(N2CCOCC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(C(=O)NCCCO)c2)n1 +Cc1ccc2c(c1)c(=O)c1c3n2CCN(C(=O)CCl)C3CC1 +CC(C(=O)O)N1C(=O)C(=Cc2ccc(-c3ccc(Cl)c(Cl)c3)o2)SC1=S +O=C(NC(Cc1ccccc1)CN1CCN(c2ncccn2)CC1)C12CC3CC(CC(C3)C1)C2 +CCNC(=O)n1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccc(F)cc3)cc21 +O=C(Nc1nc(-c2ccccc2)c(C(=O)c2ccccc2)s1)c1ccccc1 +COC1(CCO)CCN(c2nccc(Nc3cc4c(cn3)nc(C)n4C(C)C)n2)CC1 +O=C(O)c1csc(C2CCC3C(CC(O)C3C=CCOc3ccccc3)O2)n1 +N#Cc1cnc2ccc(-c3ccc(CN4CCOCC4)cc3)cc2c1NC1CC1c1ccccc1 +N#Cc1ccc(-c2cc(-c3cc4c([nH]3)CCNC4=O)ccn2)cc1 +Cc1cc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5ccc(N6CCN(C)CC6)c(F)c5)nc34)CC2)no1 +CCNC(=O)OCCc1cc(-c2cncc(OCC3CCCN3)c2)on1 +OCC1OC(n2c3ccc(Cl)cc3c3c(-c4ccco4)ncnc32)C(O)C1O +CC(C)C(Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(-c3ccncc3)nc2c1 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3C(=O)OC2CCC2)c1C +COc1ccccc1-c1cccc(N2CCN(CCOCCC(=O)NCc3ccc(F)nc3)CC2)c1 +O=c1n(Cc2ccccc2)c2sc3c(c2c2ncnn12)CCN(CC1CCOCC1)C3 +C(#Cc1ccccn1)C1=CCC(Nc2ccc3ccccc3c2)CC1 +COCCN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cn1 +CONC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(CCN4CCN(C)CC4)cc3)ncc2c1=O +Cc1ccccc1N1CCC(Oc2nc(-c3ccncn3)cc(=O)n2C)CC1 +CC1(C)COC(c2cccc(OC(=O)NC3CCCC3)c2)=N1 +CCN1CC=C(c2ccccc2)C(C(=O)OCCc2ccccc2)C1 +CCOC(=O)C=C1CC(CC)(CC)CC(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Oc1ccc(C2Nc3ccccc3-c3ccnc4[nH]cc2c34)cc1 +OCCOCCNc1nc(Nc2ccccc2)nc(Nc2ccc(F)cc2)n1 +N=C(N)c1ccc(-c2cc(-c3ccc(C(=N)N)cc3)on2)cc1 +CC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)cc1)CC1CCC(C(=O)O)CC1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Nc2ccccc2)cc1 +NC(CSC(c1ccccc1)(c1ccccc1)c1cccc(Cl)c1)C(=O)O +CC(C)(C)CN(C(=O)CCC(=O)N1CCCC(C(=O)O)C1)c1ccc(Cl)cc1C(O)c1cccc2c1OCCO2 +Cc1ccccc1S(=O)(=O)Nc1ccc2c(c1)CN(C)C(=O)N2 +COc1cc(-c2nc(-c3ccccc3)c(-c3ccc(Br)cc3)[nH]2)cc(OC)c1O +CC(C)CC(NC(=O)Nc1ccc(-c2noc(-c3cccs3)n2)cc1)C(=O)N(C)N(C)C#N +NC(CCNCc1ccccc1OCc1ccccc1)C(=O)N1CCCCC1 +Cc1ccc(C(C(=O)NC(C)C)N2C(=O)C(C3Cc4ccccc4C3)NC(=O)C2CC(C)C)cc1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CCOCC3CO)ns2)n1 +CC=C1CCC2C3CCC4CC(NC(=O)c5ccc(C#N)cc5)CCC4(C)C3CCC12C 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+Cc1noc(C2C(c3ccc(Cl)cc3)CC3CCC2N3C)c1-c1ccc(Cl)cc1 +Cc1cc(C2CCC2)c(-c2nc3c([nH]2)COCC3)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +CC(C)Cn1cnc2c(NCCCCCCC(=O)NO)nc(NCc3ccccc3)nc21 +O=C1Nc2ccc(C(=O)NC(CO)c3ccccc3)cc2C1=Cc1ccn[nH]1 +CS(=O)(=O)N1CCC(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +Cc1ccc(N(CCCCCCC(=O)NO)c2ccccn2)nc1 +CN(C)c1cccc2c(S(=O)(=O)NCCCCCCCNc3ccnc4cc(Cl)ccc34)cccc12 +CCN(CC)CCN1C(=O)C(O)(c2cc3ccccc3cc2Cl)c2c1cc(C(N)=O)cc2C(F)(F)F +CC1CN(c2noc(C(F)F)n2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Cn1cc(NC(=O)c2ccc3ccc(NC4CCCCC4N)nn23)c(C(F)(F)F)n1 +O=C(CCCn1cnc([N+](=O)[O-])n1)Nc1cccc(Cl)c1 +CNc1ncc2ncnc(Nc3cc(C(=O)Nc4cc(CN5CCCC5)cc(C(F)(F)F)c4)ccc3C)c2n1 +CN1C(=O)Cc2cc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4CC5)cc3)ccc21 +NNc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Cc1c(S(=O)(=O)NCCO)cc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)n1CC1CCCCC1 +Cc1ccc(N2CCc3ncnc(NC(C)c4cccc(Cl)c4)c3C2)nc1 +CCc1cc(OC)cc2nc(-c3cccnc3N3CCN(CCN(C)C)CC3)oc(=O)c12 +COc1ccc(CNCCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)cc1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCC4(CC4)C3)n2)cc1OC(F)F +CC(C)(C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 +COc1cccc(CNC(=O)CC2(C)CC3(CCCCC3)OO2)c1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(CCCC(=O)O)cc1)Cc1ccc(Oc2ccccc2)cc1 +CCC1OCC(O)=C2C1=NC1=C(C(=O)COC1)C2c1ccc(F)c(Cl)c1 +COc1cccc(-c2cccc(NC(=O)Nc3cc4ccc(OC5CCN(C)CC5)c(C)c4oc3=O)c2)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(NC4CCCC4)c3Cl)C2)cc1 +O=C(O)C1CN(c2cc3c(cc2F)-c2noc(-c4onc(-c5ccccc5)c4C(F)(F)F)c2CC3)C1 +CC1(Cc2ccccc2)COc2ccc(C(=O)NC3CCCCC3)cc21 +Nc1nc(N)c2nc(CNc3ccc(C(=O)NC(CCC(=O)Nc4cccc(C(=O)O)c4)C(=O)O)cc3)cnc2n1 +CC(=O)N1C2C=C(CN3C4CCC3CC(Nc3ccc5ccc(OC(C)C)cc5n3)C4)CC1CCC2 +COCCN(C)C1CCC(OC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccc(F)cc1 +CCC1(O)CCC(C)(C(=O)Nc2nc3c(OC)ccc(N4CCOCC4)c3s2)CC1 +CC(=O)Oc1c(C)cc(Cl)c2c1C(=O)C=CC2=O +Cc1ccc2c(c1)-c1nc(NCC3CCN(C(=O)C(C)C)CC3)sc1CCO2 +CCN(c1ncccc1NC(C)C)C1CCN(C(=O)c2cc3cc(NS(C)(=O)=O)ccc3[nH]2)CC1 +CC(C)(CNC(=O)c1cnc(N2CCC(CO)CC2)cn1)c1ccccc1 +CC(C)(CNS(=O)(=O)c1ccc2c(Cl)cnc(N=C(N)N)c2c1)C(=O)O +COc1ccc(-c2c(-c3ccccc3)nc3ccccn23)cc1 +CN(C)C1CCc2c(c3cc(Br)ccc3n2S(=O)(=O)c2cc(C(F)(F)F)ccc2Cl)C1 +Cc1c(CCO)sc[n+]1CCOc1ccc(Cc2ccc(OCC[n+]3csc(CCO)c3C)cc2)cc1 +O=C(Nc1ccc(N2CCN(C(=O)OC3CCCC3)CC2)nc1)c1oc(N2CCCCC2)nc1C(F)(F)F +O=C(CN1CCC(O)CC1)OC1CC2(N3CCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2 +COC(=O)C(C)(C)Cn1c(=O)[nH]c(=Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(C)cc2)c1=O +Cc1ccc(F)cc1C(=O)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +COc1ccc(C(O)=CC=Nc2cccc(C)n2)cc1OC +O=C1CSC(c2ccccc2)N1CCNc1ccnc2cc(Cl)ccc12 +CCC(=O)OC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 +COc1cc(-c2oc3ncnc(NCC4CCCO4)c3c2-c2ccccc2)ccc1OCCN1CCCCC1 +COc1ccc(C2(c3ccc(C#N)c(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1C +CC(C(c1ccc2cc(OCc3ccc(C#N)cc3)ccc2c1)n1ccnc1)N(C)C +COc1ccc(-[n+]2c(-c3ccc(Br)cc3)cn3c2CCc2ccccc2-3)cc1 +NC(=O)c1nc(-c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)nc(N2CCOCC2)n1 +CCS(=O)(=O)c1ccc(-c2ccc(-c3n[nH]c4c3Cc3cc(O)c(OC)cc3-4)cc2)cc1 +CC12CCC3C(CCC4CCCCCC43C)C1CC=C2n1ccnc1 +O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cn[nH]c1 +Cn1c(=O)n(C)c2cc(-c3[nH]c(-c4cccs4)nc3-c3ccccc3F)ccc21 +Nc1cnc(-c2ccc(C3CCC3)c(OCc3cccc(Cl)c3Cl)c2F)cn1 +CC(NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OC2CCOCC2)c1 +CCCCNS(=O)(=O)n1nc(C(=O)NC)c2c1-c1c[nH]nc1CC2 +Cc1noc(-c2c(F)cccc2C(=O)N2C3CCC2C(Nc2cnc(C(F)(F)F)cn2)C3)n1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3scnc3C)cc2)C(=O)C2CCCCC2)c1 +CC1CCCC(n2cnc(CC(CCCN)C(=O)O)c2)C1 +COc1cc(C(=N)N)ccc1-c1cc(-c2ccc(C(=N)N)cc2)on1 +N#Cc1cccc(-c2cc(C(F)(F)F)ccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)c1 +Cc1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)NC(C)(C)C)CC3)c2C)c1 +CC12CC(c3ccoc3)(c3ccoc3)C(c3ccccc31)c1cccc[n+]12 +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1cccc(Oc2cncc(-c3ccc(S(C)(=O)=O)cc3)n2)c1 +O=C(O)CON=CC=C(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +CNc1nc(Nc2cc3c(cc2Cl)C(=O)N(C)C3)ncc1C(F)(F)F +O=C(Nc1cc2ccc(C3(O)CCCCC3)nc2cn1)C1CC1 +Cc1cc(C(=O)Nc2cc(OC(C)C)cc(OC(C)C)c2)cc(C)c1OCCN +COc1ccc(S(=O)(=O)NCC(O)C(Cc2ccccc2)NCc2cc(Cl)ccc2-n2cnnn2)cc1 +CCC(Oc1ccccc1)C(=O)N(Cc1ccccc1)CC1CCCN1 +N=C(N)c1ccc2[nH]c(-c3cc(CC(=O)O)cc(-c4cccc(C(=O)O)c4)c3O)cc2c1 +Nc1ncc(CCCCc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)c(N)n1 +O=C(Cc1c[nH]c2ccc(Br)cc12)NC1CCN(Cc2ccccc2)CC1 +CC(=O)NCCC1=C(C(C)C)Cc2ccc3c(c21)CCO3 +CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc(N4CCCC4)nc3)c2)cc1 +Cc1ncc(-c2nc(C(F)(F)F)cn2-c2ccc(S(N)(=O)=O)cc2)s1 +CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(OCCF)ccc1-2 +Cc1c(C(=O)NC2CCN(C)CC2)sc2ncnc(Nc3ccc(C#N)cc3OC(CF)CF)c12 +CN1CCN(c2ccc(Nc3cc(-c4c[nH]c5ccccc45)ncn3)cc2)CC1 +COc1cccc(CNC(=O)C=C2c3ccccc3N(C(=O)c3ccc(-n4ccc(C)n4)cc3Cl)CCC2(F)F)n1 +CCN(C1CCN(Cc2cccc(C(=N)N)c2)C1=O)S(=O)(=O)c1ccc2ccc(OC)cc2c1 +NC(COc1cncc(-c2cccc3cnccc23)c1)Cc1c[nH]c2ccccc12 +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3c(Cl)cccc3Cl)c3ccccc32)CC1 +COc1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 +CCOc1n[nH]c2cc(NC(=O)NC(c3ccccc3)C(O)COC)ncc12 +N#CCc1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1 +CC(OCC1(c2ccccc2)CCC2(CN1)NC(=O)NC2=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +N=C(N)NCCCC(NC(=O)C1CCC2CN(C(=O)C(O)Cc3ccccc3)CC(=O)N21)C(=O)c1nccs1 +CCn1c(=O)c2cnc3c(OC)cccc3c2n(C2CCC(C)CC2)c1=O +CCOc1cccc(-n2cc(C(=O)N3CCN(c4ccc5ccccc5c4)CC3)nc2-c2ccc(Cl)cc2)c1 +CC(C)(C)c1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 +CC(Nc1nc(Nc2ccc(S(=O)(CC=O)=NS(=O)(=O)CC[Si](C)(C)C)cc2)ncc1Br)C(C)(C)O +COc1cc(C)c2nc3[nH]nc(C)c3c(N3CCN(C(N)=O)C(C)C3)c2c1 +Nc1nc(Nc2ccccc2)c2c(n1)[nH]c1ccccc12 +Fc1cccc(COc2cncc(-c3ccnc4[nH]c(C5CCNCC5)cc34)n2)c1 +CC(c1ccc(C(F)F)cc1)N1CCC2(CCC(O)CC2)OC1=O +COc1ccc(NC(=O)c2ccc(C)c(N(C)c3ncnc4cnc(N5CCOCC5)nc34)c2)cc1C(F)(F)F +CN(C)CCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +Nc1cccc(CN2C(=O)N(Cc3ccc4[nH]nc(N)c4c3)C(CCc3ccccc3)C(O)C2Cc2ccccc2)c1 +O=C1c2ccc(Br)cc2C(=O)c2cc(O)c(O)cc21 +COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)cn(C)c1=O)C2=O +COC(=O)c1ccc(Oc2ccc(C(=O)Nc3ccc(C4CNCCO4)cc3)cc2)cc1Cl +CCc1ccc(C(=O)NN(C(=O)c2cc(C)cc(C)c2Cl)C(C)(C)C)cc1 +COc1ncccc1CN1CC(c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C)cc3)n2)C1 +CN1CCC(C(=O)N2CC=C(c3ccc(NC(=O)N4Cc5ccncc5C4)cc3)CC2)C1 +COc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccc(F)cc3)c2=O)cc1 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+O=C(c1nn(C2CCN(CCC3CCOCC3)C2)c2c1CS(=O)(=O)c1c(F)cccc1-2)N1CCOCC1 +CNc1cc(C(=O)O)nc2c(-c3cccc(F)c3O)nc(N3CCOCC3)nc12 +Nc1ncc(C2CNC(=O)C2)cc1-c1ccc(C(=O)NC(CO)c2ccccc2)c(F)c1 +Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc([N+](=O)[O-])cc1 +OC1(c2ccc(Cl)cc2)c2cc3ccccc3cc2C2=NCCN21 +N#Cc1cccc(C(=O)NCCc2nc(-c3ccc(F)cc3)cs2)c1 +CCCCN(c1sc2ccccc2c1Br)S(=O)(=O)N(C)C +CCOC(=O)CCN1c2c(ssc2=O)Sc2ssc(=O)c21 +Cc1nc(-c2ccccn2)nc(NCC(NS(=O)(=O)CCN2CCNCC2)c2ccccc2)c1Cl +COCCNC(=O)c1cnc(Nc2ccc(OC)nc2)c(-c2nc(C)nc(N)n2)c1 +COc1cc2c(cc1OC)-c1n[nH]c(Nc3cccc(Cl)c3)c1C2 +CSc1nnc(C2CC(S)CN2S(=O)(=O)c2ccc3ccccc3c2)n1-c1c(F)c(F)cc(F)c1F +CCN1C(=O)CCC1C(=O)NCc1c(F)ccc(C)c1Cl +Cc1c(F)ccc(C(=O)Nc2cc(C(=O)OC(C)C)ccc2N2CCN(C)CC2)c1Cl +O=C(NCCc1ccc(OCCN2CCCC2)c(Br)c1)c1cccc(Cl)c1 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)Cc1nc2c(C(F)(F)F)cccc2[nH]1 +Cc1cn(C2CCCN(S(=O)(=O)c3ccc(O)c(Oc4ccc(Cl)cc4)c3)C2)c(=O)[nH]c1=O +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1CN1CCOCC1 +COc1ccc(C(=O)CC(=O)C(=O)O)cc1Cc1ccccc1 +COc1cccc(OC)c1C1CCC(=O)N1Cc1cccc(N2CCCCC2)n1 +CC(C)c1ncc(NC(=O)OCc2ccccc2)c(=O)n1CC(=O)NC(C(=O)C(F)(F)F)C(C)C +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cn(CC(C)(C)O)nc3C)nc12 +Oc1ccc2nc(-c3ccccc3)n(Cc3ccc(OCCN4CCCCC4)cc3)c2c1 +COc1nn2cc(-c3cc4c(OCc5ccc(F)cc5)cccc4o3)nc2s1 +CN1CCC(n2cnc3ccc(-c4cccc(OCC(O)CN5CCc6ccccc6C5)c4)cc32)C1 +COCCOc1cc2ncnc(N3CCN(C(S)=NCc4ccc5c(c4)OCO5)CC3)c2cc1OC +O=C(NC1CCCCC1NC(=O)c1ccc(-n2ccccc2=O)cc1)c1ccc(Cl)cc1 +COc1ccc(-c2cc(-c3ccccc3)[n+](C)c(-c3ccccc3)c2)cc1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(CCCN2CCN(C)CC2)cc1 +NC(=O)c1ccc2[nH]c(-c3ccc(-c4ccccc4)cc3)nc2c1 +OC(c1ccc(Cl)cc1)(c1ccc(Br)cc1)c1cccnc1 +[C-]#[N+]c1c(F)ccc2c1CCC2CN1CCN(CC(O)c2ccc3c(c2C)COC3=O)CC1 +Nc1ncc(C2CCOCC2)cc1-c1ccc(C(=O)NCc2ccnnc2)c(F)c1 +O=C(c1ccc(F)cc1)C1CCN(Cc2cccc(I)c2)CC1 +CCC(C(=O)Nc1ccc(-n2cnc3ccccc32)cc1)c1c[nH]c2ccc(C(=N)N)cc12 +COCCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(OCC(=O)NC4CCCC4)cc3)cc21 +CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3ccccc3c2n1Cc1ccccc1 +CCN(CC)c1ccc(C=NNc2ccnc3c(OC)cccc23)cc1 +O=S(=O)(NCCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(Cl)c1 +N=C(N)c1cccc(-c2cn(-c3cccc(C(=N)N)c3)nn2)c1 +O=C(O)c1ccc(CN2C(=O)C(=Cc3ccc(OCCc4ccccc4)cc3)SC2=Nc2ccccc2)cc1 +CC(C)c1ccccc1Sc1ccc(C=CC(=O)N2CCN(C(=O)c3ccncc3)CC2)cc1[N+](=O)[O-] +CC=CC(=O)N1CCc2[nH]c3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn3c2C1 +C=CCc1c(OC(=O)Nc2ccccc2)ccc2ccc(=O)oc12 +CC(C)(C)OC(=O)N1CCC(c2ncc(OCc3ccc(S(C)(=O)=O)cc3)cn2)CC1 +Nc1nc2c(cnn2CCCc2ccc3c(c2)OC(C(=O)O)O3)c2nc(-c3ccco3)nn12 +CCc1ncnc(N2CCN(C(=O)OC)CC2)c1C#Cc1ccc(N)nc1 +O=C(c1cnc(-c2ccccc2)nc1)N1CCC(c2nc3ccccc3[nH]2)CC1 +O=C(O)C(CC1CC1)N1CC(CN2CCC(c3[nH]c(Cc4ccccc4)nc3Cl)CC2)C(c2cccc(F)c2)C1 +O=C1CCC(CCCN2CCC3(CC2)CN(c2ccccc2)NC3=O)(c2ccc(Cl)c(Cl)c2)CN1Cc1ccccc1 +Cc1cnc2n1C(C)(Cc1ccc(Br)cc1)C(=O)N2c1cc(Cl)cc(Cl)c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCn1ncc3cc(F)ccc31)CC2 +CC(C)CNc1nccc(NCCN(C)c2cc(-c3ccccc3)nc(N)n2)n1 +COCCOc1nc(-c2ccccc2C(F)(F)F)cc2nc(-c3c(C#N)c(C(C)(C)C)nn3C)[nH]c12 +CCCc1ccc(-c2ccsc2S(=O)(=O)Nc2onc(C)c2Br)cc1 +Cc1onc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN(C)C(=O)CC(C)(C)C)c1C +O=C1N=C(NC2CC2)SC1=Cc1ccc2ncccc2c1 +O=C(NC1CCCN(c2cccc(OCCO)c2)C1)C1CC1 +CCCCCCNC(=O)N1CCN2C(=O)N(C3CC3c3ccccc3)C(=O)C2C1 +COc1cccc(N(C)C(=O)c2cnc(-c3cccc(C)c3)s2)c1 +CCCCC(NC(=O)OC(C)CC1CCCCC1)C(=O)c1nc(C(=O)OCC)cs1 +O=c1c2c3c(sc2[nH]c(=S)n1CCCn1ccnc1)CCCCCC3 +Cc1cc(COc2ccc(S(=O)(=O)N3CCC(Cc4ccccc4)(C(=O)NO)C3)cc2)c2ccccc2n1 +CS(=O)(=O)c1ccc(C(=Cc2ccc(Cl)cc2)c2ccccc2)cc1 +Cc1c(N(Cc2ccc(CC3CC3)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +NCCNCCCc1ccc(Nc2c3ccccc3nc3ccccc23)cc1 +COCCn1cc(CCNc2ncnc3c2ncn3C2OC(C(=O)NC3CC3)C(O)C2O)c2ccccc21 +N=C(N)c1cccc(OCCNC(=O)c2ccc(C(=O)N3CCCC3)cc2)c1 +O=C(O)c1nc2ccccc2n(C2CC3CCCC(C2)N3C2C=CCCCCC2)c1=O +CCc1cccc(NC(=O)c2cccc(N3CCc4c(cnc5ccsc45)C3)c2)c1 +COC(CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(=O)O +N#CC1CN(C(=O)OCc2ccccc2)CCC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +O=C(OCCCCc1ccc(O)cc1)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1 +COc1cccc(OC)c1-c1cc(NC(=O)C2(C(=O)O)CCCCC2)nn1-c1ccc(F)cc1 +CCOC(=O)c1cn(Cc2ccccc2F)c2cc(-c3ccc(N)cc3)c(CN(C)Cc3ccccc3)n2c1=O +COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(-c2ncccn2)nc1OCCOc1ncc(SC)cn1 +C=C(CCO)c1ccc(-c2ccc(C(=O)NCC(C)C)cc2C(=O)O)c(C(=O)Nc2ccc(C(=N)N)cc2)c1 +COc1ccccc1N1CCN(CCCCOc2ccn3ncc(C=O)c3c2)CC1 +CSc1nc(-c2ccc(Cl)cc2)nn1C(=O)N1CCCCC1 +O=C(CCOc1ccccc1)N1CCN(C(=O)n2sc3ncccc3c2=O)CC1 +CC(C)Oc1ccc(C(=O)Nc2cnc3c(c2)CNCC3(C)C)cc1C(F)(F)F +COc1cc2ncnc(NCc3ccc4c(c3)OCO4)c2cc1SC +CC(=O)Nc1ccc(-c2cc3sc(N4CCC(N5CCCCC5)CC4)nc3cn2)cn1 +CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)C1CN(c2ccccc2O)C(=O)O1)S(=O)(=O)c1ccc(N)cc1 +COc1ccc(OC)c(Sc2ccc3nnc(-c4ccsn4)n3n2)c1 +CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(C)cc3C#N)cc(Cl)c2NC1=O +NC1CC(N2Cc3cnc(C(F)(F)F)nc3C2)COC1c1cc(F)c(F)cc1F +CC(N)CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +CCCN=C(O)c1ccccc1N1CCN(CCCN2C(=O)C3CCCN3C2=O)CC1 +FC(F)(F)Oc1cccc(-n2nnc3ccc(N4CCC5(CCNCC5)CC4)nc32)c1 +O=C(NC(=S)NCCC1CCN(Cc2ccccc2)CC1)c1ccc2c(c1)C(=O)c1ccccc1-2 +NCc1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4sccc4c23)cc1 +Cc1ccc(NC(=O)C(CC2CCCC2)n2ccc(S(=O)(=O)C(C)C)c(Cl)c2=O)nc1 +CC(C)n1c(NC(=O)c2ccc3nc4n(c3c2)C(C)(C)CCNC4=O)nc2ccccc21 +CCN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NC1CCc2c(sc(=N)n2N)C1 +Cc1cc2c(-c3ccc(S(=O)(=O)NCCN)cc3)ccnc2[nH]1 +CCN1CCc2c(c3ccccc3n2Cc2ccc(C(=O)NO)cc2)C1 +COC(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)CC1 +Fc1cc(C(F)(F)F)cc(C(Cc2ccccc2)(Nc2nc3ccccc3[nH]2)c2ccc(Cl)cn2)c1 +CN1CCC(Nc2ccc(-c3cc4ncn(C)c(=O)c4c(N4CCC(CO)C4)n3)cc2S(C)(=O)=O)CC1 +CCOCCOC(=O)C(C#N)=C(NCc1cnc(OCC(F)(F)F)s1)C(C)C +Cc1cc(C)c(C=C2C(=O)Nc3ccc(N)cc32)[nH]1 +Cn1c(-c2ccc(Cl)cc2)c(CCC(=O)N2CCC(O)(Cc3ccccc3)CC2)c2cc(-c3ccco3)ccc21 +CCC(=O)c1c(-c2ccccc2)c2cc(Cl)ccc2c(=O)n1Cc1cc(S(C)(=O)=O)n(CC(N)=O)n1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2cccc(O)c12 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F +Cc1ccc(S(=O)(=O)n2nccc2-c2c(-c3ccc(Cl)cc3)noc2C)cc1 +O=C(NCC(NS(=O)(=O)c1ccccc1)C(=O)O)c1ccc(N2CCC(NC3=NCCCN3)CC2)c(O)c1 +O=C(O)C(=O)CC(=O)c1ccc(-c2ccc(Cl)cc2)o1 +Cc1ccc2c(C3CCN(CCN4CCNC4=O)CC3)cn(-c3ccc(F)cc3)c2c1 +Cn1cc(C(C(=O)Nc2ccc3ccccc3c2)P(=O)(O)O)c2ccccc21 +O=C(NNc1ccc(N(CCCl)CCCl)cc1)Nc1cc(-c2ccccc2)nc2ccccc12 +Nc1ccccc1NC(=O)c1ccc(C(=O)Nc2cccc(Nc3ncc(-c4cccnc4)cn3)c2)cc1 +Fc1ccc(CCNc2ccc3nnc(-c4ccc(OC(F)F)cc4)n3n2)cc1 +COC(=O)COC1CCc2c(-c3ccc(C(F)(F)F)cc3)cncc21 +c1ccc2c(c1)c1cc[n+]2CCCCC[n+]2ccc(c3ccccc32)NCc2ccc(cc2)CN1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(CCc1cccc(Oc3ccc(F)cc3)c1)CC2 +CC1CN(c2cnc3ccc(Sc4nnc5c(F)cc(-c6cnn(C)c6)cn45)cc3c2)CCO1 +c1ccc(CC2CNCCN2c2cnc3[nH]ccc3c2)cc1 +COc1ccc(CCNC(=O)C(=O)c2c[nH]c3ccccc23)cc1OC +CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1cccc(F)c1 +COc1cccc2c1-c1ccc3c(c1CO2)C(C)=CC(C)(C)N3 +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2)c1-n1cccc1 +CN1CCC(N(C)C(=O)C2CN(S(=O)(=O)c3cccc4c(Cl)cccc34)c3ccccc32)CC1 +Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)C(F)(F)F)cn3)n(C3CCC3)c2n1 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+NC(=O)C1(c2cccc(Sc3ccc(Cn4cccc4)cc3)c2)CCOCC1 +O=C(O)COc1ccc(O)c(C(=O)C=Cc2cccc(C=Cc3ccc4ccccc4n3)c2)c1 +CC1CN(c2ccc3cc([N+](=O)[O-])ccc3n2)CCN1CCCCN1C(=O)CCCC1=O +COc1ccc(Cl)cc1-n1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n2c3ccccc3nc12 +CCCCCOc1ccc(-c2ccc(-c3ccccc3Cl)n2Cc2ccc(NCCCO)c(N)n2)cc1 +CCOc1ccc(F)c(CCNC(=S)Nc2ccc(Br)cn2)c1Cl +O=C(O)CCCCCOc1ccc2[nH]c3nc(O)nc-3cc2c1 +CN(C)Cc1ccc(NC(=O)c2cccc(CNC(=O)Nc3cccc(C(N)=O)c3)c2)cc1 +COc1cc2c(cc1OC)C(CCc1ccccc1)N(C(N)=O)CC2 +CC(Oc1ccc(S(C)(=O)=O)cc1C(=O)N1Cc2ccc(C3CCOCC3)cc2C1)C(F)(F)F +Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc1nnnn12 +COc1cc2c(cc1O)CN1CCc3cc(OC)c(O)cc3C1C2 +CCOC(=O)C1(c2ccccc2)N=C(c2ccc(OC)cc2)N(Cc2ccccc2)C1c1ccc(NCc2ccc(O)cc2)cc1 +CC1CN(CCCc2ccc(C(C)(C)C)cc2)CC(C)O1 +COc1ccc2nc3cc(Cl)ccc3c(NCCNCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1 +CC1CN(C2CCN(C(=O)c3ccc4ncccc4c3)CC2)CCC1Cc1ccc(Cl)c(Cl)c1 +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1cccc(C(=O)NCCN2CCCC2)c1 +COC(=O)CCCCCCC1C(=O)CC(O)C1c1ccc(C(C)(C)C)cc1 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+CCCCCOc1ccc(C=CC(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +CCN(CC)CCCCNC(C)=Nc1ccnc2cc(Cl)ccc12 +COC(=O)C1C2CC3CCC1N3CC2=CC#Cc1cccs1 +O=S(=O)(c1cccc(-c2nn[nH]n2)c1)N1CCc2ccccc2C1 +Cc1ccccc1N1CCN(c2ccc(C(=O)NCCCN3CCCC3=O)cc2NC(=O)c2ccco2)CC1 +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4nccnc4c3=O)CC21 +Cn1cc(-c2cc(NS(C)(=O)=O)cc(Cl)c2Oc2ccccc2)c2cc[nH]c2c1=O +CCc1cc(-c2noc(-c3cc(C)nc(OC(C)C)c3)n2)cc(C)c1OCC(O)CNC(=O)CO +Cn1cc2c(nc(N=C(Nc3ccccc3)Nc3ccccc3)n3nc(-c4ccco4)nc23)n1 +CC(C)=Cc1sc(C(C)C)c(C=CC(O)CC(O)CC(=O)O)c1-c1ccc(F)cc1 +CC(C)CCCCOc1nc2c(c(=O)n(C)c(=O)n2C)n1C +CCCCc1nc2cc(C=CC(=O)NO)ccn2c1CN(C)C +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(N)nc4)cc23)c1F +CCN(CCCCCCNC1=CC(=O)c2ncccc2C1=O)Cc1ccccc1OC +CCNc1nc2ccc(C#CC(C)(C)O)cc2n1-c1ncnc(N)n1 +CCCOc1ccc(CC(NC(=O)c2ccccc2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)cc2)cc1 +CCN(CC)C(=O)c1ccc(C(=C2CCN(CC3CC3)CC2)c2ccccc2)cc1 +CC(OC(=O)Nc1conc1-c1ccc(CS(=O)(=O)CCC(=O)O)cc1)c1ccccc1Cl +CC(C)C(NC(=O)CCN1CCC(c2nc(-c3ccccn3)no2)CC1)c1ccc(Cl)cc1 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+O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NC4CCCC4O)nc23)N1 +CS(=O)(=O)Nc1ccc(N2CCN(C(=O)CCCCCOc3ccc4[nH]cc(CCN)c4c3)CC2)cc1 +CC(C)Cc1ccc(C(C)C(=O)NS(C)(=O)=O)cc1 +CCOc1cccc(OC2CCN(c3ncnc4cc(OC)c(OC)cc34)C2)c1 +NS(=O)(=O)c1cccc(Nc2nc(N3CCOCC3)nc3[nH]cnc23)c1 +CCOC(=O)CN(C(=O)c1ccccc1)c1ccc2c(c1)OC(C)(COc1ccc(C(=N)N)cc1)CN2C +CNC(=O)C(CC(C)C)NC(=O)C(Cc1ccccc1)NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12 +NC1CCC(C(=O)C2CCCN2c2nc(Nc3cc(C4CC4)[nH]n3)c3cccn3n2)C1 +CCOC(=O)C=CC(CCC(N)=O)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)SCc1ccccc1 +C=CCNc1nc(N2CCC(NCC3c4ccccc4CCc4cc(OC)ccc43)CC2)nc2c1ncn2CC=C +NCc1cc(Oc2cccc(C(=O)N3CC(O)C(F)C3)c2)nc(C(F)(F)F)c1 +O=C(O)c1cc2c(C#Cc3cccc(F)c3)c(-c3ccccc3)oc2cc1O +Cc1c(C(=O)NCCCN2CCN(c3cccc4cccnc34)CC2)cc(-c2ccccc2)n1C +NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1cccnc1-n1ccc(-c2cccc(C(F)(F)F)c2)n1 +[N-]=[N+]=CC(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1 +CN(C)c1cc2c(NC3Cc4ccccc4C3)ncnc2cn1 +[N-]=[N+]=Nc1ccc(CCC(O)C=CC2C(O)CC(O)C2CC=CCCCC(=O)O)cc1I 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+O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(Oc2cnc(OCC(F)(F)C(F)F)c(Cl)c2)cc1F +O=C(O)c1c(O)c(-c2ccc(-c3ccc(O)cc3)cc2)nc2ccccc12 +CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2)CC1 +Nc1ccc(-c2cc(C=C3CN4CCC3CC4)on2)cc1 +CC1(C)CC1C(=O)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O +O=c1n(-c2ccc(F)cc2)ccc2nc(COc3ccccc3)cn12 +Cc1c(Sc2ccc(Cl)cc2)c2ccc(Cl)cc2n1CC(=O)O +CCCCn1cc2c(nc(NC(=O)Cc3ccc4ccccc4c3)n3nc(-c4ccco4)nc23)n1 +CC1c2c([nH]c3ccc(C(F)(F)F)cc23)CC2CCN(CCc3ccccc3)CC21 +O=C(Nc1ccc(-c2ccc(C(=O)C3CCCC3C(=O)O)cc2)cc1)Nc1cccc(F)c1 +Cc1ccc2[nH]c(NC(CC#N)c3cccc(Cl)c3)nc2n1 +NS(=O)(=O)c1ccc(-n2cc(-c3nc4ccccc4[nH]3)c(-c3ccccc3)n2)cc1 +O=C(Cc1ccccc1)Nc1ccc2c(c1)Cc1c-2nc(O)c2nccn12 +CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(O)cc1 +CCN(C)C(=O)Oc1cccc2c1CCN2CCC(=O)OC +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OCC(C)(C)C)ccn5)n4)ccc3[nH]2)CC1 +CCn1cc(-c2cc3c(-c4cccc(N5CCOCC5)n4)n[nH]c3cn2)cn1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)c4cccc(F)c4)nc23)N1 +O=C(NCc1ccsc1)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CCCOc1ccc(C2CCN(c3ccc(C(C)NC(C)=O)cc3F)CC2)c(C)c1 +O=C(O)C1=CSC2C(=Cc3cc4oc5c(n4n3)CCOC5)C(=O)N12 +CC(C)NC(=O)c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(C#N)c(C(F)(F)F)c3)c2)c2cnccc21 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1sccc1CNCC(F)(F)F)O2)C(C)=CC(C)(C)N3 +CC1CCN(C(=O)C(CCCN=C(N)N)NS(=O)(=O)c2ccc3c(c2)CCCC3)CC1 +Cc1cc(Nc2nc(N3CCN(C(=O)c4ccccc4S(C)(=O)=O)CC3)nn3cccc23)n[nH]1 +O=C(c1cccnc1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 +CCNC(=O)Nc1ncc(-c2cc(-c3c(C)cc(OC)cc3C)nc(-c3cnccn3)n2)s1 +CCCN(c1nc(-c2ccc(Cl)cc2)n(C)n1)C(C1CC1)C1CC1 +CCC(C)C1C(=O)OC1C(=O)NC1CC1CC(CCCc1ccccc1)NC(=O)C(C)NC(=O)OCc1ccccc1 +COC(=N)c1nc2ccc3ncnc(Nc4ccc(C(F)(F)F)cc4)c3c2s1 +O=C(CCc1nc(-c2ccc(Cl)cc2)no1)Nc1ccc2c(c1)c1ccccc1n2CCO +COc1ccc(CO)cc1-c1cc2c(NC(C)c3ccccc3)ncnc2s1 +O=C(CCN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2)Nc1ccccc1 +COc1cc(C(=O)C=Cc2ccc(O)c(O)c2)cc(OC)c1OC +O=C(NC1COP(=O)(CCCCC2(C(=O)NCC(F)(F)F)c3ccccc3-c3ccccc32)OC1)c1ccccc1 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+O=[N+]([O-])c1cc(-c2cc3ccccc3[nH]2)ccc1-c1cc2ccc(Br)cc2[nH]1 +CCCCCC(O)C=CC1C(O)CC(=O)N1CC=CCCCC(=O)O +CCc1ncnc(-c2ccc(C(=O)N3CCC(N4CCC(C)CC4)C3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +O=C(O)c1ccc(NC(=O)c2cc3ccccc3nc2Oc2ccc(F)cc2F)cc1 +c1ccc(N2CCNCC2)c(COc2ccccc2C2CC2)c1 +Cn1cc(S(=O)(=O)c2ccc(CNC(=O)c3cc4ccncc4s3)nc2)cn1 +CCCCCCCCC=CCCCCCCCCCC1(O)C(=O)C=CC(O)C1O +CNc1ncc2cc(-c3ccccc3)c(-c3ccc(CN4CCC(c5nnc(-c6ccccn6)[nH]5)CC4)cc3)nc2n1 +COc1cc(C=C2CCCC(=Cc3cccc(Cl)c3)C2=O)cc(OC)c1 +O=C(O)c1ccc2c(c1)C(=CCCN1CCCC1)c1ccccc1CO2 +Cc1cn2cc(CNc3ncnc4ccc(N5CCCC5c5cc(F)ccc5F)nc34)nc2s1 +O=C(NC1CCC2CN(Cc3cccc(OC(F)(F)F)c3)CC21)C(C1CCCCC1)C1CCCCC1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)C1CCCCN1CC2 +NC(N)=NN=C1c2ccccc2CC1Sc1nc2ccccc2[nH]1 +CN1CC(Cc2c(F)cccc2F)CC(NC(=O)c2ccc3[nH]nc(-c4ccc5ncsc5c4)c3c2)C1 +CC(C)(C)C(=O)OCC1(CO)CC(=CCCCCCCCCCCCCCCCN=[N+]=[N-])C(=O)O1 +Cn1cc(-c2ccc3nnc(Sc4ccc5ncc(CN6CCOCC6)cc5c4)n3c2)cn1 +NC(=O)c1cnn2ccc(N3CCCC3c3cc(F)cc(OCCN4CCOCC4)c3)nc12 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+O=C(NC1N=C(c2ccccc2)c2ccccc2N(CC(F)(F)F)C1=O)N1CCC(N2Cc3ncccc3NC2=O)CC1 +CCC(C)C1NCCCCC=CCCNC(=O)C(Cc2ccccc2)NC(=O)C(C)N(C)C1=O +CN(C)c1ccc(C#Cc2ncnc(N)c2-c2cccc(Cl)c2)cc1 +C=CCCCC[N+]1(C)C2CCC1CC(CC(C#N)(c1ccccc1)c1ccccc1)C2 +O=C(CCc1ccc(-c2ccccc2)cc1)c1ncc(C(=O)C(F)(F)F)o1 +O=C1NC(=O)C(Cc2ccc(Oc3ncc(Cl)cc3Cl)cc2)S1 +CC1CCC(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)C2CCN(C(=O)c3cccnc3)CC2)CC1 +C=C=CCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O +CCOC(=O)CNC(=O)N1CCC(CC(=O)N2CCC(C3c4ncc(Br)cc4CCc4cc(Cl)cc(Br)c43)CC2)CC1 +COc1cccc(-c2ccc(C(=O)NC3CCN(CC(F)(F)F)CC3)cn2)c1 +CC(C)N1CC(C(=O)N2CCN(c3ccccc3CC3CCNCC3)CC2)C(c2ccc(Cl)cc2)C1 +NS(=O)(=O)c1ccc2c(c1)CN(C(=O)C1CCCCN1C(=O)COc1ccccc1)CC2 +CCCCCCC(C)(C)c1cc(OC)c2c(c1)OC(C)(C)c1ccc(C(=O)OCCC)cc1-2 +O=C(COc1cccc(-c2ccccc2)c1)Cn1ccc2cc(C(=O)O)ccc21 +O=C(c1ccc(F)cc1Cl)N1CCn2c(-c3ccc(F)cn3)cnc2C1 +CN(C)CCC(O)CNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)(F)C2)CCN1Cc1ccc(F)cc1 +Clc1cc(Cl)cc(CNCCCc2nc3ccc(Cl)nc3[nH]2)c1 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+C=CC(=O)NC1CN(c2nc(Nc3cnn(C)c3)c3ncn(C(C)C)c3n2)CC1F +Cc1cc(C)n2cc(C=Cc3ccc4ccccc4n3)nc2n1 +CCOC(=O)c1cnc(NCc2ccc(Cl)cc2)n2nc(-c3ccco3)nc12 +Cc1c(Sc2ccccc2)n(OCCO)c(=S)[nH]c1=O +CCC(=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O +CC1CCC(Oc2nccc(C(C)(C)O)c2F)CN1C(=O)c1ccccc1-n1ncnn1 +CCCN(CC1CC1)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 +O=C(O)CCCCCCC1C(O)CC(O)C1CCC(O)CCc1ccccc1F +Nc1c2c(nc3c1C(c1ccc([N+](=O)[O-])cc1)c1c(ccc4ccccc14)O3)CCCC2 +CCS(=O)(=O)c1ccccc1-c1ccc(-c2nnc(C3(c4ccc(Cl)cc4)CCC3)n2C)c(Cl)c1 +O=C(Cc1ccc2ccccc2c1)Nc1cc(C2CC2)n[nH]1 +O=C1NCCN1CCN1CCN(C2CC(c3ccc(F)cc3)c3cc(Cl)ccc32)CC1 +O=C(C=Cc1ccc(C(=C2C3CC4CC(C3)CC2C4)c2ccc(O)cc2)cc1)NCCCCO +COc1cc2c(cc1OC)C(=O)N(CCN1CC3CCc4c(OC)cccc4C3C1)CC2 +c1ccc(C(OCCCc2c[nH]cn2)(c2ccccc2)c2ccccc2)cc1 +CC(C)(C)C(=O)c1c[nH]c2ncc(Nc3ccc(C=C4SC(=O)N(CCN)C4=O)cc3)nc12 +O=C1OC2(CCC(N3CCC(Cc4cc(F)ccc4Br)CC3)CC2)c2ccc3c(c21)OCO3 +CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2cccc(NC(=O)CN3CCN(C(=O)CO)CC3)c2)ncc1Cl +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OCC(C)(C)OCc2ccsc2)c1 +O=C(C(O)c1ccccc1)N1CCC(c2ccc(O)cc2O)CC1 +CC1=C(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)C(=O)c2c(O)cccc2C1=O +CN1CCC=C(C2CN(S(=O)(=O)c3ccc(Cl)cc3)CCO2)C1 +Cc1cc(COc2cccc(C(C)Nc3cc(-c4cc5ccccc5n4C)nc(C)n3)c2)n(C)n1 +COc1ccc(C(C)=NNc2ncc(Cl)c(Nc3cccc(NC(=O)C=CCN(C)C)c3)n2)cc1 +Cc1cnc(C(=O)Nc2ccc(C3CCCNC3)cc2)cn1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(OCCC#N)nc3n2)cc1CO +Cc1cc(O)c(-c2ccc(C(C)N)cc2)c2c1[nH]c(=O)c1sccc12 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(F)(F)C(=O)N1CCc2ccccc2C1 +Oc1cccc(-c2ccc(-c3ccc(F)c(O)c3)cc2)c1 +O=c1cc(-c2ccncc2)oc2ccc(OCCCCCCN3CCC(O)CC3)cc12 +COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCOCC4)c(OC)cc23)c(Cl)cc1C +CN(C(=O)c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc2ncnn2c1 +OCCOc1nc(N2CCCCC2)c2nc(OCCO)nc(N3CCCCC3)c2n1 +Clc1ccc(N2CCN(CCCc3nc4ccccc4s3)CC2)cc1 +Cc1cc(OCC2CN(C)c3ccccc3O2)cc(C)c1C(=O)Nc1cc(C2(C(=O)O)CC2)ccc1Cl +CCOc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 +CC(C)CC(NC(=O)c1ccno1)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1 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+COc1ccc(N2CCN(C(CNS(=O)(=O)c3cc(F)ccc3F)c3cccnc3)CC2)cc1 +CCCCNC(=O)C(C)CC(O)C(N)CN(C(=O)c1ccc(OC)c(CCCCOC)c1)C(C)C +Cn1c(CNc2cccc(C(=O)NCc3cccc(C(F)(F)F)c3)c2)nnc1-c1ccncc1 +CC(=O)c1cn(CC(=O)N2CC(F)CC2C(=O)NCc2cccc(Cl)c2F)c2cc(CO)ccc12 +CNC(=O)c1cnc(N)c2cc(-c3ccc(S(=O)(=O)NC(C)(C)C)cc3)sc12 +CC(C)(C)OC(=O)n1c(-c2ccc3c(c2)CC(NS(C)(=O)=O)C3)cc2ccccc21 +FC(F)(F)c1cnc2[nH]c3ccc(C4CNCCO4)cc3c2c1 +CCc1ccc(Cc2sc(C3OC(CO)C(O)C(O)C3O)cc2C)cc1 +c1ccc(-c2nnc3c4c(c(OCc5nccs5)nn23)C2CCC4CC2)cc1 +Cc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +COc1cc(OCc2csc(-c3ccc(C(=O)N4CC(OC)C4)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3nccn3C)cc2)c1C +O=C(CN1CCCc2ccccc21)N1CCN(c2scnc2-c2nc3ccccc3[nH]2)CC1 +O=C(Cn1ccc(-c2ccc(C(=O)NO)s2)n1)Nc1cccc2cccnc12 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NCc4ccccc4F)nc23)N1 +Cn1cc(-c2ccc(-c3cncc4ccc(S(N)(=O)=O)cc34)cc2)cn1 +CS(=O)(=O)c1ccc(C2C(Oc3ccccc3)C(=O)N2c2ccc(Cl)cc2)cc1 +O=S(=O)(c1cccc(Cl)c1)n1cc(C2=CCCNC2)c2ccccc21 +COc1ccccc1-c1cc2c(NCc3ccncc3)ncnc2s1 +CC1CC(C)CN(C(=O)c2cc(Br)ccc2NC(=O)CCC(=O)c2ccccn2)C1 +Nc1ncc(-c2cnc3sc(-c4cccc(S(=O)(=O)N5CCOCC5)c4)nn23)cc1C(F)(F)F +COc1cc(OCc2csc(N3CCC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(N4CCCCC4)nc23)N1 +Cc1c(Cl)cccc1S(=O)(=O)N1CCCC1(C)C(=O)NC1C2CC3CC(C2)CC1C3 +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(OC)cc1)C(=O)C1CCC1 +COc1ccc(C(NC(=O)c2ccc3cnc(Nc4ccnn4C)nc3c2)c2ccnn2C)cc1F +CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)C2CC=C(C)CC32)CC1(Br)Br +Cc1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cn3)ccnc2[nH]1 +CNC(C)C(=O)NC1C(=O)N(Cc2c(C)cnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)C1C +Cc1c(O)ccc(C=NNc2ncccc2[N+](=O)[O-])c1O +O=C(Nc1ccc(Oc2ccnc3cc(-c4cn(CCCN5CCCC5)cn4)sc23)c(F)c1)N1CCN(c2ccccc2)C1=O +CS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCNCC(O)c3ccc(N)cc3)cc2)cc1OC1CCCCC1 +COc1cc(OC)cc(N(CC2CCCO2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Oc1ccc(CN2CCC(COCc3ccc(F)cc3)CC2)cc1 +CCCCCCN1CC(C)C(C)(c2cccc(O)c2)CC1CCC +O=S(=O)(c1cccc(CCCCOCCCCCCNCC(O)c2ccc(O)c(CO)c2)c1)N1CCCCC1 +CN1CCC(c2n[nH]c3ccc(NC(=O)c4ccc(F)cc4)cc23)CC1 +Cc1ccc(N(C)C(=O)c2c(-c3ccccc3Cl)noc2C)cc1 +COc1ccc(-c2csc(NC(=O)C3CCCCN3S(=O)(=O)c3ccc(C)cc3)n2)cc1 +Cc1ccc(N(C(=O)CCl)C(C(=O)NC2CCCCC2)c2cccnc2)cc1C +O=C(O)c1sc(-c2ccccc2)cc1N1C(=O)CCC1C1CCCCC1 +Cc1cc(C)n(CCCCCSc2nc(-c3ccc(N(C)C)cc3)c(-c3ccc(N(C)C)cc3)[nH]2)n1 +COC(=O)Nc1noc2cc(-c3c(-c4cnccn4)n[nH]c3C)ccc12 +O=C(C(Cc1ccc(O)cc1)NS(=O)(=O)c1cnccc1NC(CO)Cc1ccccc1)N1CCC(CCF)CC1 +O=C(Nc1cccc(Cl)n1)c1cc(Oc2cncnc2)ccn1 +CCOc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)ccc1OC(F)(F)F +CCS(=O)(=O)c1cc2cc(CC(O)(CC(C)(C)c3ccc(F)cc3C(N)=O)C(F)(F)F)[nH]c2cn1 +OC1CN(Cc2ccc(F)cc2)CCC1CCOC(c1ccccc1)c1ccccc1 +CC(=O)NCCC1=C(c2ccccc2)Cc2ccc3c(c21)CCO3 +Cc1ccc(N2CCN(S(=O)(=O)CC3CCC(N(C)c4ncnc5[nH]ccc45)CC3)CC2)nc1 +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1-n1nccn1 +COCCn1cc(-c2ccc3cnc(Nc4ccc(-c5cnc(C)n5CO)cc4OC)cc3c2)cn1 +Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(Oc4ncccn4)cc3)(C(F)(F)F)C2)cc1 +O=C(O)C1CC1C(=O)c1ccc(N(CC2CC2)c2ccc(Cl)cc2)cn1 +CNCc1cc(C#CCCN2CCOCC2)ccc1Oc1cccc(F)c1 +COc1cc(C(=O)c2c(-c3ccccc3)[nH]c3ccc(Br)cc23)cc(OC)c1OC +O=C(O)CN(Cc1cccc(-c2cc(Cl)cc(Cl)c2)c1)S(=O)(=O)c1ccc(OC(F)F)cc1 +CC1NC(=O)c2cc(-c3cccc4c(=O)n(CC(F)(F)F)c(NC(C)(C)C)nc34)[nH]c21 +CC(=O)N1CCC(n2cc(Nc3ncc4c(n3)-c3c(nn(C)c3Cc3c(Cl)cccc3Cl)CC4)cn2)CC1 +Cc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +COc1ccccc1Oc1cccc(C(=O)Nc2nc(C)cs2)c1 +Oc1nc2cc3cc(OCCCCc4nnnn4C4CCN(Cc5ccc(F)cc5)CC4)ccc3[nH]c-2n1 +Cc1cc(C)cc(-c2c(O)nc3cc(Cl)c(C(=O)Nc4nc[nH]n4)cc3c2OCCC2CCCCN2)c1 +COc1ccc(C2CN(C)Cc3cc(OCC4CCN(C(C)C)CC4)ncc32)cc1 +COC1CCC2CN(CCc3ccccc3)C1CN2Cc1ccccc1 +CCOc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)cc1 +Cc1nc(OC2CCC2)c(C(=O)NC2C3CC4CC2CC(O)(C4)C3)s1 +CCOC(=O)c1cnc(NC(C)C)n2nc(-c3ccco3)nc12 +COc1cc(OC)cc(-c2ccc(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)c(OC)c2)c1 +Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C1CCC(=O)CC1 +CC(C)C(CO)NCc1nc(C#CCCC2CCCCC2)ccc1F +COc1cccc(C2C(C(=O)C(C)(C)C)N3C=C(C#N)C=CC3C23C(=O)c2ccccc2C3=O)c1OC +O=C(O)C1CC(NC(=O)C2NC3(CCCCC3)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)C1 +CC(C)Cc1ccc(S(=O)(=O)NC(=O)OC(C)(C)C)c(-c2ccc(Cn3cncn3)cc2)c1 +CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CC3(CC3)C2)cc1 +COC1=CC(=O)c2c(COc3ccc(F)cc3)c(C)n(C)c2C1=O +CNC(=O)CC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 +O=C(Cc1cc[n+]([O-])cc1)N1CCC(C2c3ccc(Cl)c(Br)c3CCc3cc(Br)cnc32)CC1 +CC(C)CC(=O)N1CCc2nc(-c3ccncc3)nc(N(C)CCc3ccccn3)c2C1 +C=CC(=O)Nc1cccc(-n2c(=O)c(OC)cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +Cc1nc(NCC2CCC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +O=C1N(Cc2ccccc2)C(Cc2ccccc2O)C(O)C(O)C(Cc2ccccc2O)N1Cc1ccccc1 +CC1(C)C2CCC1(CS(=O)(=O)N=C(N)N)C(=O)C2 +COc1cc(C#N)cnc1C(=O)Nc1ccc(F)c(C2(CF)CC(C(F)(F)F)OC(N)=N2)c1 +NCCc1cn(C2=C(c3c[nH]c4ccc(C(F)(F)F)cc34)C(=O)NC2=O)c2ccccc12 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CCC(CN2C(=O)c3cccc4c(N)ccc(c34)C2=O)CC1 +CCc1ccc2ccc(S(=O)(=O)NC3CCN(Cc4cccc(C(=N)N)c4)C3=O)cc2c1 +CC(C)c1ccccc1OCCN1CC2CC1CN2S(=O)(=O)c1ccc(F)cc1 +NC(=O)CN1CCC(N2CC(=O)N3CCCC3C2=O)C1=O +CC(=O)Nc1cc(C2C([N+](=O)[O-])C(c3ccccc3Br)CCN2Cc2cccnc2)ccc1O +COc1cccc(COc2cc(-n3cnc4ccccc43)sc2C(N)=O)c1 +CC(CC(Cc1ccc(-c2ccccc2)cc1)NC(=O)CCC(=O)O)C(=O)O +COc1ccc2cc(-c3nc(-c4ccc([S+](C)[O-])cc4C)[nH]c3-c3ccncc3)ccc2c1 +O=S1(=O)c2ccccc2Oc2cccc(C(F)(F)F)c21 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCOc1ccc(CN3CCCCC3)cc1)C2 +O=C(O)CN1C(=O)C(NC(=O)C(S)Cc2ccccc2)CCCc2ccccc21 +O=C(C1CNCCC1(O)c1ccc(F)c(F)c1)N(Cc1cn(Cc2ncco2)c2cccc(F)c12)C1CC1 +O=CNC12Cc3c(n(CCF)c4ccccc34)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5 +Cc1ccc(S(=O)(=O)N(CC(=O)NCCc2ccc(Cl)cc2)c2ccccc2C)cc1 +O=C1OC2(CCN(Cc3ccccc3)CC2)c2c1csc2-c1ccc(-c2ccccc2)cc1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCN(C(=O)C=Cc3ccc(F)cc3)CC2)cc1 +O=C(NCCN1CCC2(CC1)C(=O)NCN2c1ccc(F)c(F)c1)c1ccc2ccccc2c1 +CC(C)S(=O)(=O)c1ccccc1Nc1nc(NN=Cc2ccco2)ncc1Cl +CC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3c(C)ccnc32)CC1 +CCCc1c(OCCCCOCCCCOc2c(C(C)=O)ccc(OCC(=O)O)c2CCC)ccc(C(C)=O)c1O +CC(C)CN(CCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)CC(C)C +Cc1cc(Nc2nccc3nc(-c4c(Cl)cc(C#N)cc4Cl)[nH]c23)ncn1 +Cc1n[nH]c2c1C13CC1CN(C(=O)OC(C)(C)C)C3=CC2=O +COC1C(OC(=O)NC(C(=O)NN2CCOCC2)C(C)C)CCC2(CO2)C1C1(C)OC1CC=C(C)C +O=C(NCc1cccs1)c1nc(-c2cccs2)nc(O)c1O +Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccccc3)cc12 +Cc1ccccc1-n1c(Cn2nc(-c3ccc4nc(N)oc4c3)c3c(N)ncnc32)cc2cccc(C)c2c1=O +Clc1ccc2c(c1)CCc1cccnc1C2=C1CCN(CCc2cccnc2)CC1 +CCCCN(CCCC)c1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1cccc2c(C3=C(c4nnc5ccccn45)C(=O)NC3=O)cn(C)c12 +Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(N3CCC(O)C3)nc12 +O=C(O)CC(NC(=O)CNC(=O)CCCNc1ccccn1)c1cccc([N+](=O)[O-])c1 +O=C(C=Cc1cccn(CCc2cccc(Br)c2)c1=O)NO +O=C(O)c1cc(C(F)(F)F)ccc1N1CCC(Oc2ccc(F)cc2)C1 +COc1ncc(-n2nc3c(c2C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1 +NC1CCN(c2nc(Nc3cc(C4CC4)[nH]n3)c3cc(Cl)ccc3n2)CC1 +CCOC(=O)C(CC(C)C)N(Cc1ccc(N)cc1)S(=O)(=O)c1ccc(Cn2c(C)nc3cnccc32)cc1 +CCCc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc32)cn1 +O=C(c1cn(-c2ccc3c(c2)OCCO3)c(-c2ccc(F)cc2)n1)N1CCN(c2cnc3ccccc3c2)CC1 +O=C(NN1CCN(c2nc(-c3cnc4ccccc4n3)no2)CC1)C1CCCCC1 +Cc1cccc(Cl)c1Nc1nc2c(F)cccc2n2cncc12 +CS(=O)(=O)NCCCCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +COCC(C)NCc1cccnc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CCN)CC1 +CNc1ccc(-c2cn(-c3ccc(OCCOCCOCCF)cc3)nn2)cc1 +CCOc1ccc(NC(=O)c2ccc(F)c(S(=O)(=O)NC3CCCC(C)C3C)c2)cc1 +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1[nH]cnc2ncnc1-2 +O=C(Nc1ccc2c(c1)CCN2)NC1CCCCC1CN1CCCC(Cc2ccc(F)cc2)C1 +Cc1ccc(S(=O)(=O)Nc2ccc(-c3nc4ccc(NS(=O)(=O)c5ccc(C)cc5)cc4[nH]3)cc2)cc1 +O=C1c2ccc(O)cc2OC(c2ccc(OCCN3CCCCC3)cc2)C1c1ccc(O)cc1 +O=C(C1CCc2c(Cl)cc(OCC3CCCCC3)c(=O)n21)N1CCCC1 +Cc1c(C(C)C)c(=O)on1C(=O)N1CCC(Cc2ccccc2)CC1 +CC(C(=O)OC1C[N+]2(CCCc3cc4ccccc4s3)CCC1CC2)(c1ccccc1)N1CCCCC1 +COCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl +NC(=O)CNC(=O)c1cccc(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1 +Cc1cnc(C(=O)N2CCCC(Nc3ccc(C(F)(F)F)cn3)C2C)c(-n2nccn2)c1 +Cc1sc2nc(N3CCC(C(N)=O)C3)nc(N3CCC(CNCCC4CCCCN4C)CC3)c2c1C +COc1ccc(C2Nc3cccc(O)c3C(=O)N2Cc2ccccc2)cc1COc1ccc(NC(C)=O)cc1 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+CCCNC(=O)c1ncc2c(=O)n(Cc3ccccc3)ccc2c1O +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)N2CCCC2C(=O)NO)C(=O)O)cc1 +N#CC1(n2cc(C(NC(=O)c3csc(-c4ccccc4)c3)C3CCCCC3)nn2)CC1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)C=[N+]=[N-] +COc1cc2cc(CO)c(CO)c(-c3ccnc(-n4ncc5ccccc5c4=O)c3)c2cc1OC +O=C(Nc1ccc(Cl)cc1)NC1CCCC1NC(=O)c1ccc(-n2ccccc2=O)cc1 +O=C1N(CCCCCCCO)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1CCCCCCCO +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(Cl)cc1CN1CCC(F)(F)C1 +NS(=O)(=O)c1nnc(NCc2cn(-c3ccccc3)nn2)s1 +Cc1ccc2oc(=O)n(CCCCn3cc(CCCCCC4SCC5NC(=O)NC54)nn3)c2c1 +Cn1ncc(-c2ccncc2)c1-c1ccc(OCc2cc(OCCOCCOCCF)c3ccccc3n2)cc1 +Cc1cc2nc(CCC3CCCN3C)n(Cc3ccc(Cl)cc3)c2cc1C +Brc1cc(Br)c2c(c1)C(NCCCNc1nc3ccccc3[nH]1)CCN2 +CC(C)=CCCC(C)=CCCC(C)=CCc1c(O)c2cc(C)c(C)cc2oc1=O +Cc1nccc2c1[nH]c1cc(OCCCN(C)C)ccc12 +CCCN1CC2CC(c3cc(F)ccc3F)(S(=O)(=O)c3ccc(Cl)cc3)CCC2NS1(=O)=O +CCc1cc(NC(=O)NC2CCCN(CCCc3ccc(F)cc3)C2)cc(-c2nnnn2C)c1 +Cc1cc(Nc2nc(NC(C)c3ncc(F)cn3)nc(N3CCOCC3)c2Cl)n[nH]1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(Cl)c(C(F)(F)F)c3)nn21 +CCCCCCCCCCCCCCCCCC(=O)OCC(O)COP(=O)(O)OC1C(O)C(O)C(O)C(O)C1O +CCCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1ccc(Cl)cc1Cl +Cc1ccc2cccc(OCc3c(Cl)ccc(S(=O)(=O)NC(C)(C)C(=O)NCC4CCNCC4)c3Cl)c2n1 +COc1ccccc1-c1nc2ccc(-c3cccc(CN4CCC4)c3)cc2c(=O)n1CC(=O)NC(C)C +CC1(c2nc(NC(=O)c3ncc(C#CCO)cc3Cl)ccc2F)N=C(N)OCC1(F)F +OC(c1cccc(F)c1)(c1cccc(F)c1)C12CC[N+](CCOCc3ccccc3)(CC1)CC2 +O=C1C(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1c1ccc(-c2ccccc2)cc1F +C#Cc1cccc(NC(=O)c2ccccc2C(=O)c2ccc3nc(NC(=O)OC)[nH]c3c2)c1 +CS(=O)(=O)N1CCC(CNC(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1 +O=C(C1CSCN1C(=O)CC1CCc2ccccc2C1)N1CCSC1 +Nc1nnc(-c2ccc3[nH]cc(-c4cncc(N5CCC(F)(F)C5)n4)c3c2)o1 +CN(C)CCn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2CCC2CC2)CC1 +c1ccc(CNC2C3CCN(CC3)C2C(c2ccccc2)c2ccccc2)cc1 +O=C(Nc1ccccc1)N1CCN(Cc2cccc(Br)c2)CC1 +COc1ccc(-c2sc3c(c2CN(C)Cc2ccccc2)c(=O)n(CC(C)C)c(=O)n3Cc2c(F)cccc2F)cc1 +Cc1ccc2c(N3CCN(CCc4cccc5c4OCC(=O)N5CC4CC4)CC3)cccc2n1 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+FC(F)(F)c1cccc(N2CCN(CCC3CCC(Nc4ncccn4)CC3)CC2)c1 +CCCCCCS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O +OC(COCc1ccccc1)CN1CCC2(CC1)OCc1c2ccc2ccccc12 +NS(=O)(=O)c1ccc(N2N=C(c3cccs3)CC2c2ccc(C(F)(F)F)cc2)cc1 +Nc1nc(-c2cccc(F)c2)nc2sc(Cc3ccccc3)cc12 +CC(=O)NCc1cc(-c2cc3nc(NC4CC4)c4ncn(C)c4n3n2)ccc1F +CC(C)NCc1cc(NC(=O)Nc2cccc3c2C2CCCN2C3=O)[nH]n1 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C4CCN(C)CC4)cc3)cc12 +O=C(Nc1ccc(-c2nnc(NCCCCN3CCC(F)CC3)o2)cc1)c1ccccc1F +COc1ccc2cnc(Nc3ccccc3)nc2c1C1CCCC1 +O=C(Nc1ncc(CCNc2ncnc3ccsc23)s1)NC1CCCCC1 +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1NN=C(C)C +COc1cc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)ccc1OCC1CCCN1 +COc1ccc2nc(C(=O)Nc3ccc(C4CCNC4)cc3)ccc2c1 +CC(C)CCN(CC(O)C(Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)OCc1ccccc1)C(=O)NC(C)(C)C +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc2cc(F)ccc2c1 +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCN(C(=O)C2CCC2)C1 +O=C(C1CC(N2CCN(c3ccnc4ccccc34)CC2)CN1)N1CCSC1 +N#Cc1ccc(N2CCN(CCNC(=O)c3ccc(F)cc3)CC2)cc1 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+CCN(CC)C(=O)OC1=C(c2cccs2)Oc2cccnc2-n2cccc21 +COc1ccc(-n2nnnc2-c2ccccc2)cc1CNC1CCCNC1c1ccccc1 +COc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N5CCCN(C(C)C)CC5)cc4c3)n2)c1 +CCC1Cn2nc(-c3ccc(Cl)cc3Cl)c3nc(C)cc(c32)N1CC1CC1 +N#Cc1cc(-c2ccnc(Nc3ccnc(CN4CCOCC4)c3)n2)cnc1N1CCC(F)C1 +CC(C)Oc1ccc(-c2nn(C(C)c3oc4ccc(F)cc4c(=O)c3-c3cccc(F)c3)c3ncnc(N)c23)cc1F +NCCN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)N4CCCCC4)nc23)N1 +CC(=O)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1cnccc1-c1ccccc1 +COCCn1c(=O)c(C(C)=O)c(NC(C)=O)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc21 +CC(C)(C)C1CCC(CN2C(=N)N(CCCCC3CNC(=N)N3CCc3cccnc3)CC2Cc2ccccc2)CC1 +CCN(CC)c1nc2c(c(-c3cc(F)ccc3Br)c1CN)c(=O)n(C)c(=O)n2C +O=c1c2ccccc2ncn1CCCCCN1CCN(Cc2ccccc2)CC1 +COc1ccccc1C(=O)NCC1(c2ccccc2)CCC(=O)CC1 +COc1ccc(C=C2C=C(CCN3CCOCC3)c3ccccc32)c2ccccc12 +NS(=O)(=O)Nc1ccc(NC(=O)C=C2CC(C(=O)O)Nc3cc(Cl)cc(Cl)c32)cc1 +COc1cc(O)cc(-c2cc(=O)c3cc4c(cc3[nH]2)OCO4)c1 +Clc1ccc(C(Cn2ccnc2)OCc2ccsc2Cl)c(Cl)c1 +COC(=O)C(=O)N1CCc2c(c(-c3ccc(Cl)c(C)c3)nn2CC(O)CN2CCN(c3ccccc3C#N)CC2)C1 +O=C(c1ccc(F)cc1F)N1CCn2nc(COc3cccc(F)c3)cc2C1 +Cn1c(=O)n(C2CCCOC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)c(F)cc3ncc21 +O=C(NN=CC(Br)=Cc1ccccc1)c1ccc(F)cc1 +COCCn1nccc1-c1cc(Cl)ccc1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1C#N +CCCOc1cccc2c1-c1cc(O)cc3c1C(C2)N(C)CC3 +COC1C(C)CC2(Cc3ccc(C#N)cc3C23N=C(N)N(CC(C)(C)F)C3=O)CC1C +COC(=O)CC(O)CC(O)C=Cn1c(C(C)C)cc(-c2cccc(Cl)c2)c1-c1ccc(F)cc1 +COc1cccc(OCCNC(=O)c2cc([N+](=O)[O-])cc([N+](=O)[O-])c2)c1 +COc1cccc(OC)c1-c1ccc(CC(NC(=O)C2(S(=O)(=O)CCN3CCOCC3)CCCNC2)C(=O)O)cc1 +CCCC(C(N)=O)C(CC(C)C)C(=O)NC1CCCCN(Cc2cccc(-c3ccc(F)cc3)c2)C1=O +O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2ccc(Cl)c(Cl)c2)CC1 +CN(CCc1ccccc1)C(C(=O)c1ccc2c(c1)OCO2)c1nnnn1-c1ccccc1NC(=O)OC(C)(C)C +Cc1cccc(F)c1-c1nc(C(=O)Nc2cnn(C)c2C2CCC(N)C(F)CO2)c(N)s1 +CCS(=O)(=O)c1ccc(-c2ccc(-c3nnc(C4(c5ccc(Cl)cc5)CCC4)n3C)c(Cl)c2)cc1 +CC(C)(C)c1ccc(C(=O)NC(=S)Nc2cc(C(C)(C)C)ccc2O)cc1 +CC(C)=CCCC(C)=CCCC(C)=CCCC1(C)CCc2cc3c(c(C)c2O1)CN(CCO)CO3 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+CCCCN(CCCCCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)[nH]1)c1nc2ccccc2o1 +Clc1ccc2c(NCCCN3CCN(CCCNCCCc4ccccc4)CC3)ccnc2c1 +Cc1cc(=O)oc2c(OCCCN(C)C)c3oc4ccccc4c3cc12 +CC(C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)N1CC(Oc2ccc(Cl)c(O)c2)C1 +Cc1noc(C)c1Cn1cc(C)c2cc(F)cc(C=CC(=O)NS(=O)(=O)c3ccc(F)c(F)c3)c21 +Cc1[nH]c(-c2cc(Cl)ccc2Cl)nc1C(=O)N=C(N)N +COc1ccc(C(C)(C)C)cc1Cn1c(C(=O)NCC2(CO)CC2)cc2cc(C#N)ccc21 +COc1cc(-c2cc(=O)c3cc(Br)cc(Br)c3o2)ccc1O +CC1CN(Cc2cccnc2)CC1c1nn2c(C3CCOCC3)ncc2c(=O)[nH]1 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)c3c(Cl)cncc3Cl)CC2)cc1 +CNCC(=O)NC(CC(C)C)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)N2CCCC2=O)CC1 +CN1CCN2c3c(cccc31)C1CCN(CCCC(=O)c3ccc(F)cc3)CCC12 +O=C(Cn1nc2ccccc2n1)NCC1CCCN2CCCCC12 +Cc1ncnc(-c2ccc(S(C)(=O)=O)cc2)c1C#Cc1ccc(N)nc1 +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3ccccc3F)ccc21 +COc1ccc2c(c1)-c1nc(N)nc(-c3ccc(Br)o3)c1C2 +O=C(Nc1cncc(C(=O)c2cn(C(CO)CO)c3ncncc23)c1)c1cccc(OC(F)(F)F)c1 +O=c1nc2oc(CCCCCCCCCOCCCCCl)cc2cn1C1CC(O)C(CO)O1 +N#Cc1ccc(C(=O)Nc2ccc(C3CNCCO3)cc2Cl)cn1 +CN(C)C(=O)C(NC(=O)C(CN(O)C=O)c1ccc(Cl)cc1)C(C)(C)C +CNC1CCN(c2ccc(-n3ncc4cc(-c5ccc(Cl)cc5)sc4c3=O)cn2)C1 +COc1cc2c(cc1OC)CN(CCCCNC(=O)c1cn(Cc3ccc(O)cc3)nn1)CC2 +Cc1cc(-c2ncc(CNC(=O)c3ccc4c(c3)[nH]c3ccccc34)cc2C)ccn1 +Cc1ccccc1C=c1[nH]c(=O)c(=Cc2ncoc2C(C)(C)C)[nH]c1=O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(-n5cccn5)cc4F)nc23)N1 +O=c1[nH]cnc2ccc(Cc3nnc4ccc(-c5ccccc5)nn34)cc12 +CC(C)c1nn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-n3cnc(-n4ccnc4)c3)c12 +CCc1ccc(CN2CCc3c(c(=O)n(CCN(C)CCc4ccccn4)c(=O)n3Cc3c(F)cccc3F)C2)cc1 +CN1CCC(O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)sc2C2CC3C2)C1=O +O=c1oc2ccccc2c2nc3c(c(-c4ccccc4)c12)CCCC3=Cc1ccccc1 +O=S(=O)(c1ccc(Cl)cc1)C1(c2cc(F)ccc2F)CCC(CO)CC1 +CCc1cc(C(F)(F)F)nn1-c1nc(-c2cccc3[nH]ccc23)nc(N2CCOCC2)n1 +CCNC(=O)N1CCCC12CCCN(c1ncnc3[nH]ccc13)C2 +C=CCNCC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1 +COc1ccc(C(=O)NC2CCN(CCn3c(=O)ccc4ncc(F)cc43)CC2)cc1Cl +CC(C)CC(NC(=O)c1ccc2ccccc2c1)C(=O)NC1CCOCC1=O +O=C(NCC1CCOC1)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CCCc1cc(Oc2ccc(S(C)(=O)=O)cc2)ccc1OCCCOc1ccc(C2SC(=O)NC2=O)cc1 +Cc1ccc(-[n+]2c(-c3ccc(Br)cc3)cn3c2CCc2ccc4cccnc4c2-3)cc1 +CC(C)C(NC(=O)Cn1c(-c2ccc(F)cc2)ncc(N)c1=O)C(=O)c1nnc(-c2ccccc2)o1 +Fc1ccc(-c2[nH]c(SCCCc3ccccc3)nc2-c2ccncc2)cc1 +CN(c1nc2ccccc2[nH]1)C1CCN(CC2=CCC3CC2C3(C)C)CC1 +O=C(NCCCCN1CCN2c3ccccc3CCC2C1)c1ccc2ccccc2c1 +Cc1oc(-c2ccccc2)nc1CN1CC(C(=O)NCc2cccc(N)n2)CC(c2ccccc2)C1 +NC1(c2ccccc2)CCC(N2CC(NC(=O)CNC(=O)c3cccc(C(F)(F)F)c3)C2)CC1 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OCC(=O)NCC(=O)O)cc2)C1O +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C(CO)C(N)=O +CC(C)CNc1nc(C#Cc2ccccc2F)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +CC1=CCC2C(C1)c1c(O)cc(C(C)(C)c3ccc(C)cc3)cc1OC2(C)C +Cn1nc(-c2ccc(F)cc2)c(-c2ccc3nc(NC(=O)c4ccncc4)cn3n2)c1C1CCN(Cc2nccs2)CC1 +NC(=O)N1CCCc2cc(-c3cncc(-c4cc[nH]n4)c3)cnc21 +CC(C)N1CCN(c2nc(-c3ccncn3)cc(=O)n2C)C(C)C1 +COc1ccc(I)c(Sc2nc3c(N)ncnc3n2CCCNC(C)C)c1 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+C#CCN(Cc1cc2c(=O)n(C)c(C)nc2cc1Cl)c1ccc(C(=O)NCc2nc3ccccc3[nH]2)cc1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(CCC(C)C)Oc1ccccc1-3 +CCCCC(=O)N1CCN(c2nc(N)n3nc(-c4ccco4)nc3n2)CC1 +COCCCOc1cc(CN(C(=O)C2CNCCO2)C2CC2)cc2ccccc12 +CN(CCO)c1nc(Cl)nc(Nc2ccc(S(N)(=O)=O)cc2)n1 +COc1ccccc1CN=C(S)Nc1ccc2nc(N3CCN(C)CC3)cc(C)c2c1 +CCn1ncc2c(NC3CCOCC3)c(C(=O)N(C)Cc3ccccc3)cnc21 +COc1cc(OC2CCCc3ccccc32)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +CC(=O)N(N=C1Sc2ccccc2C1=O)c1ccc(C)cc1C +CCCCCCCNC(=O)Oc1ccc2c(c1)CN1CCCc3ccccc3C1N2C +CCCN1CCCCC1c1nc2c(C(N)=O)cccc2[nH]1 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(C=O)Cc1ccc(O)cc1 +COCn1ncc(OC)c(-c2ccc(OCCCN3CCCC3C)cc2)c1=O +Cn1nc(C(C)(C)C)c(Cl)c1-c1nc2cc(-c3ccccc3F)ncc2[nH]1 +Cc1cc(Cl)ccc1-c1cccc(C(O)CCC2CCCC(=O)N2CCSCCCC(=O)O)c1 +CS(=O)(=O)NCc1ccc(-n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)cc1 +O=c1c2scc(-c3ccccc3)c2ncn1-c1ccccc1F +c1ccc(-c2ccc(CN3CCC(c4nc5ccccc5[nH]4)CC3)cc2)cc1 +COC1CCC2(CC1)Cc1ccc(C#CC3CC3)cc1C21N=C(N)c2c(F)cccc21 +NC1CN(c2ncnc(N3CCC(F)(F)C3)n2)CC1N1CC(F)(F)CCC1=O +CCOC(=O)c1cn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)n1 +CC12CCC(=O)C=C1CCC1C2CCC2(C)C(O)CCC12 +Fc1ccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)cc1 +CC(OCC(c1ccccc1)N1CCN(CC(=O)O)CC1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=C(CSC(c1ccc(Br)cc1)c1ccc(Br)cc1)NCCCCc1ccccc1 +CN(CCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N1CCCC1)CC2)S(=O)(=O)C1CCC1 +O=C(O)c1ccc(S(=O)(=O)Oc2ccc(C=C[N+](=O)[O-])cc2)c(O)c1 +O=C(c1cccc(C#Cc2ccccn2)c1)N1CCN(c2ccccn2)CC1 +Cc1ccsc1-c1nn(CCC(C)C)c(=O)c(C2=NS(=O)(=O)c3cc(OCC(N)=O)ccc3N2)c1O +CCCn1c(C)c(C(=O)c2ccc(OC)c3ccccc23)c2ccccc21 +COc1cccc(Nc2nc3c(-c4nnc[nH]4)cccc3c3cnccc23)c1 +CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCO)N(c1ccc(-c3ccoc3)cc1)C2=O +COc1cccc2c3c(c(C)nc12)CCN3c1ccccc1 +COc1cc(NC(=O)c2ccc(C)c(Nc3ncnc4c(N)nc(N5CCN(C)CC5)nc34)c2)cc(C(F)(F)F)c1 +Nc1ncnc2c(CN3CC(O)C(O)C3CO)c[nH]c12 +Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(C(F)(F)F)c1 +CC1(C)CC(O)CN(S(=O)(=O)c2ccc(OCc3cc(Cl)ccc3F)cc2)C1C(=O)NO 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+Cc1cccc2cc(Cn3nc(-c4ccc(O)c(F)c4)c4c(N)ncnc43)n(-c3ccccc3F)c(=O)c12 +NS(=O)(=O)c1ccc(C(=O)NCC(=O)NCC(=O)NC(Cc2ccc([N+](=O)[O-])cc2)C(=O)O)cc1 +O=C(C1CCCN(c2ccc3nc(C4(n5nccn5)CC4)[nH]c3n2)C1)N1CCCC1 +CN(C)CCCCc1[nH]nc(N)c1-c1nc2ccccc2s1 +CCCn1c(=O)c2nc(-c3ccc(NC(=O)Nc4cccc(Cl)c4)cc3)[nH]c2n(CCC)c1=O +Cn1c(CC(=O)Nc2ccc(F)c(F)c2)nc(N2CCOCC2)cc1=O +CCc1cc(S(=O)(=O)N2CC(c3ccccc3)NC2=O)ccc1NC(=O)NC1CCCCC1 +C[N+]1(CCOc2ccccc2)C2CCC1CC(CC(C#N)(c1ccccc1)c1ccccc1)C2 +O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1ccccc1 +CC1(C)C(=O)NC(=O)c2c1ccc1[nH]c(Nc3c(Br)cc(Br)cc3Br)nc21 +CC(c1ccccc1)N(O)C(=O)Cc1ccc(OCc2ccccc2)cc1 +CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OC(CCc1ccc(OC)c(OC)c1)c1ccccc1 +O=S(=O)(c1ccccc1)N(Cc1ccc(OC(F)(F)F)cc1)c1nc2ccccn2c1Br +Cc1ccc(CNc2ccc3nnc(-c4ccccc4)n3n2)cc1 +N#Cc1cc(N2CCN(CCC3CCC(NS(=O)(=O)c4cccnc4)CC3)CC2)cc(C(F)(F)F)c1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CC3CN(C(=O)OCc4ccccc4)CC3C2)cc1 +Cc1cc(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)cc(-c2nc3ccccc3o2)c1O +COc1ccc(S(=O)(=O)C(CC(=O)NO)CC(C)C)cc1OC1CCCC1 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+O=C(c1ccc(Cl)cc1)N1CCc2c(n(Cc3ccc(O)cc3)c3ccccc23)C1 +COc1cc2oc(-c3ccc(O)c(O)c3)c(OC)c(=O)c2c(O)c1OC +Cn1ccc2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCOCC3)c21 +Cc1cccc(-c2[nH]c(CNC(=S)c3cccc(C#N)c3)nc2-c2ccc3ncnn3c2)n1 +O=C(NC1N=C(c2ccccc2)c2ccccc2N(CC(F)(F)F)C1=O)N1CCC(N2CCNC2=O)CC1 +COc1cc2c(Oc3ccc(-c4cnc(Nc5ccccc5)n(C)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 +CC=CC(C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +CN(C)CCn1nc2c3c(c(NCCC4CCCN4C)ccc31)C(=O)c1ccncc1-2 +O=S(=O)(Cc1cccc(OCc2ccc(CN3CCCC3CO)cc2)c1)c1ccccc1 +COc1ccc(-c2c3nc(cc4ccc(cc5nc(cc6ccc2[nH]6)C=C5)[nH]4)C=C3)cc1 +O=C(Nc1ccc(S(=O)(=O)N2CCC(O)CC2)cc1)c1ccc([N+](=O)[O-])o1 +CN(C)CCSc1c(S(=O)(=O)c2ccccc2)no[n+]1[O-] +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccc4cc[nH]c4c3)sc12 +O=C(CO)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)CC12CC3CC(CC(C3)C1)C2 +Cn1nc(-c2ccc(C(=O)O)cc2)sc1=NC1CCCCC1 +Cc1ccc(Oc2ccc(C(=O)c3nc(C(=O)O)cc4cc(O)c(O)cc34)cc2F)cc1 +N#Cc1cccc(-c2c[nH]c3ncc(-c4cncc(NS(=O)(=O)c5ccccc5)c4)cc23)c1 +NC(=O)N1CCCc2cc(-c3cncc(CC(=O)N4CCC(O)C4)c3)cnc21 +CCC(C(C)S(=O)(=O)CC)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CCCCCN(C(=O)c1ccc(Br)cc1)C(CC)c1nc2ccccc2c(=O)n1-c1ccccc1OC +O=C(NCCN1CCOCC1)c1nc(Nc2ccccc2Cl)nc(Nc2cc(C3CC3)n[nH]2)c1[N+](=O)[O-] +CN1CCC(NC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1 +O=C(CCc1ccccc1)c1ccccc1OCC(O)CNC(c1ccccc1)C1CCCCC1 +CN(CC(=O)Nc1nccc(Nc2ccc(S(N)(=O)=O)cc2)n1)C(=N)N +Cc1ccc2sc(S(=O)(=O)NC(=O)Nc3ncc(Br)s3)cc2c1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(CC(C)C)cc2CO)c1C +COCCCc1cc(CN(C(=O)C2CNCCC2(O)c2ccc(F)c(F)c2)C2CC2)cc(OCCOC)c1 +Cc1cc(-c2nc(-c3ccc(Cl)c(OC(F)F)c3)n3c2CCOCC3)cc(C)n1 +CCNCCS(=O)(=O)CCC1OCCC2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OCC12 +CC(CN1CCC(n2c(=O)[nH]c3cc(F)ccc32)CC1)NC(=O)c1ccc(F)cc1 +OCCNCCNc1nc2ccc(F)cc2c2[nH]c3ccccc3c12 +Fc1ccccc1-c1cc(-c2c[nH]nc2-c2ccccn2)ccn1 +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCCCN)C(=O)O)cc1 +CC1CN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2F)CC(C)C1(O)c1ccc(C(F)(F)F)cc1 +CC(C)Nc1cncc(-c2cnc3[nH]nc(-c4nc5c(-c6cncc(F)c6)cncc5[nH]4)c3c2)c1 +CCN1CCN(c2ccc(S(=O)(=O)N3CCCCC3)cc2NC(=O)Cc2c(Cl)cccc2Cl)CC1 +CC(Cc1cc2cc(-c3ncccc3C#N)ccc2nc1N)C(=O)NCCC(C)(C)C +CCCCOc1ccc(S(=O)(=O)N2CC(=NO)CC2C(=O)NO)cc1 +O=C(OC1(C2COCC(CC3CC3)N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CC2CC1CN2CCO +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)cc1-c1cc(F)cc(F)c1 +CCOC(O)=C1C(COCCNc2nc(N)n(C)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +COc1ccc(C(=CC=CC(=O)NC(CCCc2cccnc2)C(C)C)c2ccc(OC)cc2)cc1 +CC(C)(C)OC(=O)NC1CCCN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)C1 +Cc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)NCC3CCCC3)cc1)C2 +CN1CCN(c2cc(N3CCCCC3C(=O)NCCc3ccc(C#N)cc3)nc(C(F)(F)F)n2)CC1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(Cc1ccc(Br)cc1)C2 +O=C(NC(C(=O)N1CCCCC1)c1ccccc1)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1 +CCSCC1OC(n2cnc3c(N)nc(NN=CCC(C)C)nc32)C(O)C1O +O=C1OC2(CCN(CCc3c[nH]c4ccc(F)cc34)CC2)CN1Cc1ccc(Cl)cc1 +O=C(Nc1c[nH]nc1C(=O)Nc1ccc(CN2CCOCC2)cc1)c1ccccc1 +O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1ccc(-c2ccccc2Cl)s1 +Cc1ccc2c(c1)-c1nc(O)c(O)nc1C2(C)CC(=O)O +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCNCC3)cc12 +Cc1ccc(COc2ccc3nc(CC(C)(C)C(=O)O)n(Cc4ccc(Br)cc4)c3c2)nc1 +C1=CCOCc2cc(ccc2N2CCOCC2)Nc2nccc(n2)-c2cccc(c2)COC1 +C[S+]([O-])(CCN)=NP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1O +Oc1cccc(-c2cc(O)c3cc4c(cc3n2)OCO4)c1 +CNC(C)C(=O)NC1CCCC2CC3CCN(C(=O)OCc4ccccc4)CC3N2C1=O +Cc1cc(C)n2cc(C=Cc3nc(-c4cnccn4)cn3C)nc2n1 +O=C(c1nn(C2CCCN(CC3CCOC3)C2)c2c1CS(=O)(=O)c1c(F)cccc1-2)N1CCOCC1 +Cc1cc(Nc2cc(C(F)F)ccn2)nc(-c2ccc(C(C)(O)C3CCC(C(=O)OC(C)C)CC3)nc2)c1 +O=C(Nc1ccc2c(c1)C(N1CCN(C(=O)c3ccc4[nH]ccc4c3)CC1)c1ccccc1-2)c1ccco1 +Clc1ccccc1CNc1ncc(Br)c(Nc2cc(C3CC3)[nH]n2)n1 +COc1ccc(-c2ssc(=O)c2-c2cc(OC)c(OC)c(OC)c2)cc1 +CC(C)(NS(=O)(=O)c1cccc(OC2CCCC2)c1)c1ccc(Cn2ccc(=O)[nH]c2=O)cc1 +CNC(=O)c1cccc(-n2ccc3cnc(Nc4cc(OC)c(OC)c(OC)c4)nc32)c1 +O=S(=O)(Nc1cc(Cl)cnc1Oc1cccnn1)c1ccc(Cl)c(Cl)c1 +CC(NC(=O)C(=O)C(CCCCNC(=O)N1CCOCC1)NC(=O)OCC1(Cc2ccncc2)CCC1)c1ccccc1 +CC1CN(Cc2cncnc2)CC1c1nn2c(C3CCOCC3)ncc2c(=O)[nH]1 +COc1ccc(Cl)cc1-c1nc(CN(C)Cc2ccccc2)c[nH]1 +Cc1cccc(S(=O)(=O)Nc2ccc(C)n(CC(=O)NCCONC(=N)N)c2=O)c1 +COc1ccc(C2=NN(C3CCCCCC3)C(=O)C2(C)C)cc1OCc1ccccn1 +COc1cc(OCc2csc(-c3ccc(C(=O)N(C)CC4CC4)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(NCc1ccccc1)c1cc(C2CCNCC2COc2ccc3c(c2)OCO3)ccc1F +CCOC(=O)C1C2CCC(CC1c1ccc(-c3ccc(-c4ccccc4)n3C)cc1)N2 +COc1ccc(CCNC(=O)CN(c2cccc(Br)c2)S(=O)(=O)c2ccc(C)cc2)cc1OC +O=C(NCC(O)CO)c1cnn2ccc(N3CCCC3c3cc(F)ccc3C(F)(F)F)nc12 +Cc1c(Cc2c(F)cccc2F)nc(SCc2ccncc2)[nH]c1=O +CCn1c(C)c(C(c2ccc(F)cc2)n2ccnc2)c2ccccc21 +Cc1cc2c(C(C)C)c(O)c(O)c(C(=O)O)c2cc1Cc1ccc(C(F)(F)F)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccnc(-c2cncnc2)c1 +CN1CCN(c2ccc(Nc3ncc4ccc(-c5ccccc5)n4n3)cc2)CC1 +CC(COC(=O)NCCCn1ccnc1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(C2CC2C(=O)Nc2nc3ccc(-c4cc[nH]c(=O)c4)cc3s2)cc1 +CCCOc1cccc(O)c1-c1cc(C2CCCNC2)c(C#N)c(N)n1 +CN(C)CCN(C)c1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 +C[N+](C)(CCCCOc1c(Br)cc(Br)cc1Br)Cc1ccc([N+](=O)[O-])o1 +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCCCCCCC#N)c3C(C1)C2 +Cc1ccc(C(=O)NC2CC2)cc1Nc1nncc2c1cnn2-c1ccc(F)cc1F +CCc1cccc(-c2[nH]c(CNc3ccc(C(N)=O)cc3)nc2-c2ccc3c(c2)OCO3)n1 +CNCC(CC1CCCCC1)NC(=O)N1CCCC(C(OCCNC(=O)OC)c2cccc(F)c2F)C1 +O=C(c1ncco1)C1COc2cc(Oc3ccccc3)ccc2C1 +COc1cc(C=C[N+](=O)[O-])c(C=Cc2ccc(-c3ccccc3)cc2)c(OC)c1OC +O=C(c1c(F)cccc1-n1nccn1)N1CCC2CN(c3nc4cc(Cl)ccc4o3)C2C1 +CC(C)CCNC(CC(C)C)C(=O)NC(Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C +Fc1ccccc1Cn1ccc2cnc(Nc3ccc(N4CCOCC4)cc3)nc21 +CCCCCCCCCCCC(=O)c1c(O)c(-c2ccc(O)cc2)c[nH]c1=O +Cc1cc2c(-c3cccc4[nH]ncc34)cnc(NC3CCNCC3)c2[nH]c1=O +N#Cc1ccc2c(c1)CCN(CCC1CCC(NC(=O)C=Cc3ccc(F)cc3)CC1)C2 +OC(CN1c2cccc(-c3cccc(OC(F)(F)F)c3)c2CCC1c1cccc(C(F)(F)F)c1)C(F)(F)F +CCCCNC(=S)N(Cc1cccs1)Cc1cc2cc(C)ccc2[nH]c1=O +O=C(CNc1cccc(C(=O)NCCN2CCOCC2)c1)NN=Cc1ccncc1 +CC1Cc2cc3c(C(F)(F)F)cc(O)nc3cc2NC1C +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3nc4ccccc4s3)cc2)no1 +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1cccc(N)n1 +Nc1ccc(C(=O)OC(Cc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(OC(F)F)c(OCC3CC3)c2)cc1OCC1CC1 +NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ncnc3[nH]cc(C4CC4)c23)CC1 +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)N4CCC(N(C)C)C4)c4ccc(C)cc34)cc2)c1C +c1ccc(-c2ccnc(Nc3ccc(-n4cncn4)cc3)n2)cc1 +CC(C)(C#N)c1ccc(Nc2c(C(N)=O)cnc3ccc(-c4cnc5ccccc5c4)cc23)cc1 +CC(C)Cn1cc(-c2ccc(-c3c4c(nn3C)CCc3cnc(Nc5ccn(CCN(C)C)n5)nc3-4)cc2)cn1 +Cc1ccc(NC(=O)c2c(N=Cc3ccc4ccccc4c3)c(C#N)c3n2CCC3)cc1 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(C#N)c2OC2CCC2)nc1 +Cc1ccc(Cn2c(CCc3ccccc3)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)cc1 +O=C(NCCN1CCCCC1)c1cc(F)cc(C(F)(F)F)c1 +CC(C)C1(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC(=O)N(c2ccccc2CN2CCOCC2)C1 +CC(C)CCNc1ccc(-c2cnc3ccc(N4CCC(N(C)C)CC4)nn23)cn1 +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C12CN(c1nc3ccc(C(=O)O)cc3s1)CC2c1ccc(C#N)cc1 +Cc1noc(C)c1-c1nc(C(=O)Nc2cnn(C)c2N2CCCC(N)CC2)c(N)s1 +Cc1ccc(-c2cc(N3CCC(NS(C)(=O)=O)CC3)ncc2Cl)nc1 +Cc1ccccc1-c1cc(C(=O)Nc2cccc(C(=O)O)c2)c(CCC23CC4CC(CC(C4)C2)C3)[nH]1 +O=C(CN1CCCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)N1CCOCC1 +COc1cnc(C(=O)Nc2cc(F)c(F)c(C3(C)CC(c4c(C)noc4C)SC(N)=N3)c2)cn1 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+O=C(c1ccc2cc(C(=O)N3CCC(N4CCCC4)CC3)ccc2c1)N1CCC(N2CCCC2)CC1 +Cn1cnc2c(-c3cnc(OCCC4CCN(C(C)(C)C)CC4)c(C(F)(F)F)c3)nc(C#N)nc21 +O=S(=O)(c1ccc(-c2ccccc2)cc1)N1CCC(c2ncc[nH]2)CC1 +NS(=O)(=O)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 +CCCc1nc2c(s1)C(c1cc(Cl)ccc1OCC(=O)O)N(C(=O)OCc1ccccc1)CC2 +COc1ccccc1N1CCCN(CCCCNC(=O)c2ccc(C)s2)CC1 +Cc1cccnc1-c1cc(N2CCC(C(=O)NC3CCC(O)CC3)CC2)ncc1Cl +Fc1ccc(CC2CCC(c3ccc(Cl)cc3Cl)N(c3ccc(Cl)cc3)C2)cc1F +CN(CC(=O)O)C(=O)c1cc(Sc2cnc(Nc3cccc(Br)n3)s2)ccc1O +CC(C(=O)NCc1ccc(C(F)(F)F)nc1C=CC(C)(C)C)c1ccc(NS(C)(=O)=O)c(F)c1 +C=C(C(=O)O)C1CCC(C)C2(O)CC(=O)C(C)=C2C1 +COc1ccc(Br)c(O)c1C(=O)NCC1CCCN1Cc1ccccc1 +O=C(C1CCc2c(Cl)cc(OCc3ccc(Cl)c(Cl)c3)c(=O)n21)N1CCCC1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)C)cn2)nc(-c2ncccn2)nc1OCC#CCO +CC(C(=O)NC1CCC1)c1ccc(OC2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 +NC(=O)Nc1cc(-c2ccnn2-c2ccc(F)cc2)ccn1 +FC(F)(F)c1ccccc1CCN1CCN(c2nc3ccsc3n3cccc23)CC1 +C=CC(=O)Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2n1 +O=C(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)C(F)(F)F +CN(c1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccccc1)C2)S(C)(=O)=O +CC(C)CC(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(N)=O +COc1ccc2[nH]cc(Cc3n[nH]c(=O)o3)c2c1 +O=C(O)CCC=CCC1C(F)CCC1CNS(=O)(=O)c1ccc(F)cc1 +CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(-c3cnccn3)n2n1 +Cc1nn(C)c2nnc(Nc3ccc(S(=O)(=O)N4CCNCC4)cc3)nc12 +CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CCN(CCO)CC2)n1 +O=C(O)CN(CC(=O)NC(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)C(=O)O)S(=O)(=O)c1cccs1 +CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCCCCC2)c1 +COc1ccc(N2CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCN(C5CC5)CC4)cc3)CC2)cc1 +Cc1cc(Nc2nccn3c(-c4cn[nH]c4)cnc23)sn1 +C=CC1C(=C)C(=O)Oc2ccc3ccc(O)cc3c21 +COCCNc1cc(NC(=O)N2CCCc3cc(CN(CCN(C)C)C(C)=O)c(C=O)nc32)ncc1C#N +Nc1nc(N)c2nc(CNc3ccc(C(=O)NC(CCC(=O)Nc4ccc5c(c4)OCO5)C(=O)O)cc3)cnc2n1 +Nc1ccc2[nH]cc(C3CCN(C(C(=O)O)C4CCN(C(=O)C=Cc5cc(F)c(F)c(F)c5)CC4)CC3)c2c1 +CCn1nnc(-c2ccc3c(=O)c4cc(O)ccc4oc3c2)n1 +O=C(NC(=O)c1c(O)cccc1O)NC1c2ccccc2-c2ccccc21 +Cc1nnc(-c2cccc3ccccc23)c2cn(-c3cccc(Br)c3)nc12 +O=C(NC(=S)NCCC1CCN(Cc2ccccc2)CC1)c1ccccc1 +COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(S(C)(=O)=O)cc1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CN(C(=O)C5(O)CCC5)CC4C3)nc21 +Cc1ccc(-n2nc(C(F)(F)F)cc2-c2ccc3c(c2)NC(=O)CO3)cc1 +CC(C)c1c(Cn2ccnc2)c2ccccc2n1CCC(=O)O +CCC12CCCN(C(=O)c3ccc4nc[nH]c4c3)C1CCc1ccccc12 +CC(C)CC(O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)N(Cc2ccccn2)Cc2ccccn2)CC1 +Cc1ccc(CCCC(=O)c2ccc(COCC(C)(N)COP(=O)(O)O)c(F)c2)cc1 +CCCc1cccnc1COc1nn2c(-c3ccccc3)nnc2c2c1C1CCC2CC1 +O=C(NC(Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)N1CCC(F)(F)C1 +CC(CN(C)C)Oc1ccc(Cl)cc1NC(=O)Nc1cnc(C#N)cn1 +CCNC(CC(C)C)C(=O)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)C(=O)CS +CC(C)(C(=O)N1CCN(c2noc(-c3cc(F)c(OCC(N)CO)cc3Cl)n2)CC1)C(F)(F)F +CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)c3c([nH]2)CCCC3)c1O +COC(=O)c1nn(C(=O)c2ccsc2)c2ccc([N+](=O)[O-])cc12 +COCC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1 +CC(C)(C)c1ccc(C=Cc2nc3cc(-c4ccccc4CO)ccc3[nH]2)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NCC(F)C(C)(C)O +O=C1Cn2c(Cl)cnc(c2=O)NC(Cc2ccccc2)CNCCCCCOc2ccccc2CN1 +CC(C)c1ccccc1N1CCN(C(=O)c2ccc(F)cc2Cl)CC1=O +Cc1ccc(C2=C(C(=O)Nc3ccno3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +COc1cc2c(ccn2-c2ccnc3ccccc23)c(OC)c1OC +CC(C)CNC(=O)c1ccc(OC2CCN(CC3CCCCC3)CC2)c(Cl)c1 +O=c1cc(OCCc2ccc(F)cc2)ccn1-c1ccc(OCCN2CCCC2)cc1 +Cc1cn(CC(NC(=O)OCc2ccccc2)C(=O)O)c(=O)nc1N1CCC(Nc2nc3ccccc3[nH]2)CC1 +CSCC(NC(=O)C(Cc1ccccc1)NC(=O)N1CCC(=O)CC1)C(=O)NC(CC1CCCCC1)C(O)C(O)CC(C)C +Cc1ccc(S(=O)(=O)n2c(=O)[nH]c3ccc(Cl)cc32)cc1C +O=C(CCC1N=C(c2ccccc2F)c2ccccc2NC1=O)OCc1ccccc1 +Cc1ccccc1C(=O)OCc1coc2cc(O)cc(O)c2c1=O +COc1ccc(C(CNC(=O)Nc2cc(Cl)cc(Cl)c2)N2CCN(C3CCCCC3)CC2)cc1 +Cc1ccccc1C(=O)Nc1cccc(CNc2ncnc3c(C(N)=O)cccc23)c1 +CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(C2CC(=O)NS2(=O)=O)cc1)c1nc2ccccc2[nH]1 +COc1ccccc1-n1nc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1-c1ccc(Cl)cc1 +CCN(CC)CCOc1ccc(-c2cc(C(=O)NC3CCCNC3)c(NC(N)=O)s2)cc1 +Cc1ccc(CNC(=O)c2cccc(-n3cc(NC(=O)Nc4ccccc4Cl)cn3)c2)cn1 +Cc1cncc2c1C(NC(=O)Cc1cccc(C(F)(F)F)c1Cl)CO2 +c1ccc2sc(NC3=NCC4(CN5CCC4CC5)O3)nc2c1 +CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(OC(=O)c3ccccc3)c3ccccc23)CC1 +CC(C)(C)C(N)C(=O)N1CC(c2cc(F)ccc2F)=CC1c1ccccc1 +COc1ccc(C2(Cc3ccccc3)CCNC2=O)cc1OC1CCCC1 +Nc1nc(N2CCN3CCCCC3C2)nc2nc(-c3ccco3)nn12 +O=C(NCC1CCc2n[nH]cc2C1)C1CCCN1C(=O)C(CC1CCCCC1)NS(=O)(=O)Cc1ccccc1 +O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1F +CS(=O)(=O)c1ccc(OC2CCCCC2)c(C(=O)N2CCN(c3ccc(C#N)cc3F)CC2)c1 +CC1(C)Cc2c(n(CC(N)C(=O)O)c(=O)[nH]c2=O)C1 +O=C(CCCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCc2ccccc2C1 +CC(=O)CSc1cc(F)c(F)cc1-c1ccc(OCc2cccc(C(=O)N3CCCC3C(=O)O)c2)cc1 +COc1cnc2c(NCc3nnc4ccc(-c5cc(F)cc(F)c5)nn34)ccnc2c1 +COc1ccc2ccc(=O)oc2c1C1=NN(S(=O)(=O)c2ccc(Cl)cc2)C(c2ccc(C(F)(F)F)cc2)C1 +CCOc1ccc(CC(NC(=O)c2cccc(C)c2)C(=O)NC(Cc2cccnc2)C(=O)NCc2ccc(CN)cc2)cc1 +CC1CC(C#N)C(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CO1 +COC(=O)c1sccc1S(=O)(=O)N1c2cc(Cl)ccc2NC(=O)C1C +COc1cccc(-n2cc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)cn2)c1 +CC(C)c1ccccc1N1CCN(CCCCCCC(=O)N2CCCC2C(N)=O)CC1 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+COc1cc(NC(=O)c2cc3ccccc3o2)ccc1-c1cnco1 +COCCOc1cc2ncnc(NC3=CC(=O)C(N4CC4C)=CC3=O)c2cc1OC +CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NC1CCNC1 +N#CC1CC(NCC(=O)O)CCC1n1cc(C(N)=O)c(Nc2ccc(S(=O)(=O)C(F)(F)F)cc2)n1 +COc1ccc(CCCc2c(N)ncnc2C#Cc2ccc(N3CCOCC3)nc2)cc1 +O=C1COc2ccc(OC3CCN(CCOc4cccc5ccccc45)CC3)cc2N1 +Cc1ccc(C)c2nc3c(C(=O)NCCCN(C)CCCNC(=O)c4cccc5nc6c(C)ccc(C)c6nc45)cccc3nc12 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)c3)c2cc1OC +O=S(=O)(Nc1cc(F)c(Oc2cncc(Cl)c2)c(Cl)c1)c1ccc(Cl)cc1Cl +Cc1ccc2ncnc(NCc3ccc4c(c3)OCO4)c2c1 +Cc1coc2cc(Cl)c(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc43)cc12 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccccc4OC(F)F)ncc23)ccn1 +Cc1nc2c3c(c(C(=O)N(C)C)cc2n1C)CCC(c1ccc(Cl)cc1Cl)O3 +Nc1ncc(-c2ccccc2)nc1C(=O)Nc1ccccc1N1CCC(N)CC1 +O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2c(F)cccc12 +O=C(OCc1ccccc1)N1Cc2c(nc3ccccc3c2O)C1c1ccc2c(c1)OCO2 +CNc1noc2c(-c3ccc4c(OC(C)C)nncc4c3)c(C)ccc12 +O=[N+]([O-])c1ccc(-c2csc3ncnc(NCc4ccccc4)c23)cc1 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+CCCCc1nc2ccc(O)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 +O=C(CC1SC(c2ccccc2)N(CC2CCCO2)C1=O)N1CCC(N2Cc3ccccc3NC2=O)CC1 +COc1ccc(-c2cc(O)c(SCc3ccccc3)c(=O)o2)cc1C +Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccccc1S(=O)(=O)N1CCOCC1 +CC(=O)c1ccc(-c2ccc(CC(=O)NCc3ccco3)cc2)cc1 +N=C(N)c1cccc(N2CCCCN(C3CCN(S(=O)(=O)Cc4ccccc4)CC3)C2=O)c1 +CC(Nc1ncnc2[nH]c(-c3ccc(OCCCCCCC(=O)NO)cc3)cc12)c1ccccc1 +N=C(NO)c1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F +CCOc1cc(-c2c(C)[nH]c3cc(OC)c(Cl)cc3c2=O)ccc1F +CC(C)(C)OC(=O)N1CCC(CNc2nccnc2Oc2ccc(Nc3ccccn3)cc2)CC1 +CCCCN(C)C(=O)Cn1c2nc3ccccc3c(C)c2c(=O)n1-c1ccc(F)cc1 +O=C(OC(CO)C(F)(F)F)N1CC2C(C1)C2c1ccn(-c2ccc(F)cc2)n1 +CCn1cc(-c2cnc(N)c(-c3ccc(C(=O)NC(CO)c4cccc(F)c4)c(F)c3)c2)cn1 +O=C(CCc1cn(Cc2ccc(F)cc2)c2ccc(F)cc12)Nc1ccncc1 +CCN1CCN(c2ccc(-c3cc4ncn(C)c(=O)c4c(NCCCO)n3)cc2)CC1 +COC1C(=O)N2C(C(=O)OCc3ccc(C(C)(C)C)cc3)=C(COC(C)=O)CS(=O)(=O)C12 +CC(C)Oc1cc(-c2ccc(CCNC(C)C(O)c3ccc(O)cc3)cc2)ccc1C(=O)O +COc1cc(C=C2N=C(NCC3CC3)N(C(C)c3ccc(F)cc3)C2=O)ccc1-n1cnc(C)c1 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+COc1cc2nc(N3CCC(C(=O)NCCO)CC3)nc(N)c2cc1OC +Cc1ccc(Nc2c(-c3ccc(F)cc3)nc3n2CCN(C(=O)CN)C3(C)C)cc1 +CC1C2Cc3ccc(C(=O)NCCc4ccc(Br)cc4)cc3C1(C)CCN2CC1CC1 +CCc1nc(N2CCCCC2)c2[nH]c(-c3ccccc3)cc2n1 +COc1ccc2c3c(c4cc(OC)c(OC)cc4c2c1)C(O)C1CCCCN1C3 +Cc1cc(-c2ccccc2)nn1CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 +O=C(c1ccccc1OC(F)(F)C(F)F)N1CCC2CN(c3ccnc(-c4ccccc4)n3)C2C1 +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3CCOCC3)cc2n1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2F)nc1-c1ccoc1C +CCNc1c(C=NO)ccc(-c2ccccc2)c1-c1ccccc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N(C)C)c3F)C2)cc1 +CCCCCCC(C)NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 +CCC(O)(CC)c1ccc2cc(-c3n[nH]c4ccsc34)[nH]c2c1 +CCN1CCC(NCCC(c2ccccc2)c2ccccc2)CC1 +O=C(NCCCNCc1cc(Cl)cc(Cl)c1)Nc1cccc(O)c1 +Cc1ccc(C(=O)NCc2ccc(C(C)(C)C)cc2)cc1Nc1ncnc2cnc(N(C)CCN(C)C)nc12 +COc1ccc(-c2cccn3nc(Nc4ccc(C5CCN(CC(=O)N(C)C)CC5)cc4)nc23)c(F)c1 +CNc1c(C=N)cccc1CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +COc1ccc(F)c(F)c1-c1cccc(C(=O)c2nc3nc(N4CCC(N(C)C)CC4)ccc3[nH]2)c1 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+COCC(=O)NC1CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)C1 +CCN(CC)C(=O)C1CCC2C3CNC4=CC(=O)C=CC4(C)C3CCC12C +CC(C)(C)c1cc(NC(=O)C2CCCCN2C(=O)N2CCOCC2)no1 +O=C(c1cc(O)cc(O)c1)N1CCC(NCc2ccnc3ccccc23)CC1Cc1ccccc1 +CC(C)n1cc(-c2ccc(-c3cnc(N)c(Cl)c3N3CCC4(CCNC4=O)CC3)cc2)cn1 +COc1ccc(C(=O)OC2C=CC(=O)C3(CC(=O)OC3C=C(C)CCC=C(C)C)C2)c(OC)c1 +O=C(CCCCC1CCSS1)NCCCCNc1c2c(nc3ccccc13)CCCC2 +CN(C)CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +COc1ccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)cn1 +CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(C#Cc4cnc(N)cn4)c3)cc2C(F)(F)F)CC1 +CN(c1ccccc1)c1ncnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12 +Cc1cc(O)cc(C)c1CC(N)C(=O)NC1CCN(C(=O)C(C)C)c2ccc(Cc3ccccc3)cc21 +CCN(CCCCCCNC(=O)COc1ccc(C=Cc2cc(OC)cc(OC)c2)cc1)Cc1ccccc1OC +COc1ccc(-c2nnc(N3CCC(N4CCCC4)CC3)s2)cc1 +CC(=O)N1CCN(C(=O)c2cccc(Cc3cnc(NC(=O)c4ccc(N(C)C)cc4)s3)c2)CC1 +CN(Cc1ccc(CN2CCCNCCNCCCNCC2)cc1)Cc1ccccn1 +O=C(NCc1ccc(-c2cc(NC(=O)c3ccc(OCCN4CCCC4)cc3)[nH]n2)cc1)OCc1ccccc1 +Cc1nc(N)c2[nH]c(=O)n(Cc3ccccc3)c2c1C +COc1ccc2nc3cc(Cl)ccc3c(NC(c3ccc(Cl)cc3)c3ccc(CN4CCCC4)cc3)c2c1 +O=C(O)C1CCCC(NCc2cc([N+](=O)[O-])cc3nc(O)c(O)nc23)C1 +Cc1ccc(S(=O)(=O)Nc2cc(SCC(=O)O)c(O)c3ccccc23)cc1[N+](=O)[O-] +CCc1ccc2c(c1)C(c1ccc(OCCN3CCCCC3)cc1)Cc1cc(O)cc(C)c1-2 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2NS(=O)(=O)c1ccc2ccccc2c1 +CC12CCN(C(=O)C3CCC(O)(C(F)(F)F)CC3)C(Cc3ccccc31)C2(C)C +Cc1nc2ccc(-c3n[nH]c4ccc(C(=O)NC5CCCC(O)(Cc6ccccc6F)C5)cc34)cc2s1 +COc1ccc(-c2ccc(C(=O)CCc3ccc4ccccc4c3C(=O)NO)cc2)cc1 +Oc1cccc(-c2nc(-c3ccccn3)cc(N3CCOCC3)n2)c1 +O=C(c1ccc(Br)cc1F)c1cccn1-c1cc(F)c(O)c(F)c1 +COCCC(C(=O)Nc1ccc2cc(C(=O)O)[nH]c2c1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O +CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C2c3cc(F)cc(C4CC4)c3CC2O)C1 +O=C(Nc1cccc(-n2ccc3c(NC(=O)c4ccccc4)nccc32)c1)Nc1cccc(C(F)(F)F)c1 +CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NCCc3cccs3)CC2)nc1C(F)(F)F +CN(C)c1ccnc2sc3c(=O)n(-c4ccc(C#N)cc4)ccc3c12 +CC(C)Nc1nc(NC2CCC(NC(=O)C3CCCN(C)C3)CC2)c2cc(-c3cccc(Cl)c3)ccc2n1 +CC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1CC(N)=O +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(C2SNc3ccccc32)CC1 +CC(C)=CC(=O)NC1CCC2(C)C(CCC3C4CC=C(C(C)N(C)C)C4(C)CCC32)C1O +CC1NC(c2ccc(=O)n(C(F)F)c2)=NC1(c1ccc(F)cc1)c1ccc(F)nc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)NC1CCCCC1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 +CN1C(CCc2ccc(O)cc2)CCCC1CCc1ccc(OCCF)cc1 +O=C(c1ccc([N+](=O)[O-])s1)N1CCN(c2ccc(C(F)(F)F)cn2)CC1 +COc1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1F)=NC2 +COc1cc(Nc2cc(C(F)(F)F)nc(-c3cnccn3)n2)cc(OC)c1 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)c3ccccc3N)CC2)cc1 +CCOc1ccccc1-c1ccc(-c2cc(NCCC(=O)O)c3ccccc3n2)cc1 +O=c1cc(-c2ccccc2)oc2c(CN3CCSCC3)c(O)c(O)c(O)c12 +COc1cc(N2C(=O)C(OC(C)=O)C2c2ccc([N+](=O)[O-])o2)cc(OC)c1OC +CCn1cnc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c21 +CCN1CCC(c2ccc(Nc3cc(N(C)C(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)ncn3)cc2)CC1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3cccc(F)c3)cc2)C(=O)NC(C)C)c1 +Cc1cc(Cl)c2ncc(NC(=O)Nc3ccc(F)cc3F)c(-c3ccccc3Cl)c2c1 +CCn1c(=O)n(C2CCCN(c3ccnc(-c4cccc(F)c4)n3)C2)c2ccccc21 +Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3ccc(Cl)cc3C2=O)c(Cl)c1 +CCC(Cn1cc(C#N)c2ccccc21)NS(=O)(=O)c1c(N)cc(Cl)cc1Cl +c1ccc(-c2ncc3cc(-n4ccnc4)ccc3n2)cc1 +CCC(CC#N)NC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +Cc1nc(C)c(-c2nc(-c3cc(F)ccc3C)cc3cnc(NC(=O)C4CC4)cc23)s1 +O=S(=O)(CCCc1ccccc1)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1 +O=C(CCCCC(=O)Nc1ccc(CC(=O)C(F)(F)C(F)(F)F)cc1)Nc1ccccc1 +Cc1c2c(n3c1CCCN1CCCCC1C(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +Cc1[nH]c2ccc(Cl)cc2c(=O)c1-c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 +O=C(CCCCCCc1ccc2ccccc2c1)c1ncc(-c2ccccn2)o1 +Cc1cn(CCC2CCCCC2)c2cc(C(=O)Nc3c(Cl)cncc3Cl)ccc12 +COc1c(C)cnc(C2CC23C(=O)Nc2ccc(Cl)cc23)c1C +CC1(C)N2Cc3ccccc3CC2C(=O)N1C(CCC(=O)O)C(=O)O +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(F)cc1-c1ccc(F)c(F)c1 +Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1 +COc1cn(C)c(=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)ccc1OC)C2=O +CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1cccc(OC(F)(F)F)c1 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+CC1=CCC(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)C2CCC(O)(COC3CCOC3)CC2)CC1 +Cc1ccc(C)c(-c2ccc(C#Cc3csc(C)n3)cn2)c1 +OCC1CCC(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)CC1 +Clc1ccc(Nc2nc(C(Cl)(Cl)Cl)nc3ccsc23)c(Cl)c1 +CN(CCCn1c(=O)[nH]c2ccccc2c1=O)Cc1ccccc1 +CCN(CC)C(=O)c1ccc(C=NNC(=O)c2ccc(O)c(Cl)c2)c2ccccc12 +Cc1ccc2c(c1)nc1n2CC(N)C(c2cc(F)c(F)cc2F)C1 +O=C(C=Cc1cccc(S(=O)(=O)n2ccc3cccnc32)c1)NO +Cc1ccc2c(c1)c1c(n2CCc2ccc(C(F)(F)F)cc2)CCN(C)C1 +Cc1cc(CN2CCCC2C)ccc1C(=O)Cn1ccc(OCc2ccc(Br)cn2)nc1=O +CCCCNC(=O)c1ccn2c(NCc3ccc(NC(=N)N)cc3)cnc2c1 +Cc1cc(NC(=O)Nc2ccc(-c3nccc4[nH]nc(N)c34)cc2)ccc1F +CC(C)(N)C(=O)NC(CCCc1ccccc1)C(=O)N1C2CCC1CC(c1ccccc1C(=O)O)C2 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cn(CCN2CCOCC2)c2ccccc2c1=O +O=C(NC1CC1)c1cncc(-c2noc(C3CCCCN3C(=O)COc3ccccc3)n2)c1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4cn5c(C)cccc5n4)ncc23)ccn1 +CC(C)(C#N)COC(=O)N1CCC(C#N)C(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)C1 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ccc(Cl)cc2)CC1c1cccs1 +OC1CCC(Nc2cc(-c3cccc(NCC4COCCO4)n3)c(Cl)cn2)CC1 +CCOC(=O)C1=C(C)N=C(C)C(=C(O)OCC)C1c1ccccc1-n1ccnc1 +O=C(O)c1ccccc1-c1ccc(CCc2ncc(Cc3ccccc3)[nH]2)cc1 +CC(Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1cc(F)ccc1Cl +Cc1nc(C(C)(C)NC(=O)c2cnc(C3CC3)c(-c3cccc(Cl)c3)n2)no1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2CCC3C)n1 +CN(CC1CCCO1)C(=O)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +COC1CCN(c2nc3ccc(NC(=O)c4c(C(=O)N5CCOCC5)cnn4C)cn3n2)C1 +CCOc1ccc(Br)cc1-c1cc(Nc2cccc(C#N)c2)nc(N)n1 +CCCCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O +Fc1ccc(CNCCCNc2ccnc3cc(Cl)ccc23)cc1 +CC(=O)C(C)N(CC(F)(F)F)c1ccc2[nH]c(=O)cc(C(F)(F)F)c2c1 +CC(=O)N1CCC(n2nc(C(N)=O)c3c2-c2nc(NC4CCCC4)ncc2CC3)CC1 +CNC(=O)C=C1COc2c1ccc(OS(=O)(=O)CCC(F)(F)F)c2C +O=C(NCC(NS(=O)(=O)c1ccc(C(F)(F)F)cc1)C(=O)O)c1ccc2c(cnn2CCCNc2ncc[nH]2)c1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc(-c4cccs4)cn3)C12 +CCCOc1ccc(-c2ccc(C(=O)NCC(C)(C)C)cc2C(=O)O)c(C(=O)Nc2ccc3c(N)nccc3c2)n1 +CN(C)C(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1 +CC(=O)N1CCC(CN(C)C(=O)c2ccc(S(=O)(=O)Nc3ccccc3)cc2)CC1 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+O=C(NC1c2ccccc2CC1O)C(SCc1ccccc1)C(O)C(O)C(SCc1ccccc1)C(=O)NC1c2ccccc2CC1O +O=C(c1ccc(F)cc1)c1oc2cc(O)ccc2c1-c1cccc2ccccc12 +Nc1nccc(-c2cc3c([nH]2)C(CCC(F)(F)F)CNC3=O)n1 +COc1ccc(CC(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)C(=O)O)cc1 +COC(=O)C1CCc2cc(Nc3nc(C)cc(Nc4cc(C5CC5)n[nH]4)n3)ccc2N1 +CC(C)N1CCN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCC3)CNC5=O)nc2)CC1 +O=C1c2ccccc2C(=O)C1CC#CCN1CCCCCCC1 +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(Cc3cccnc3)C2=O)cc1 +CC(O)CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1 +O=C(NO)c1cnc(NC2(c3ccccc3)CCCC2)nc1 +O=C(Nc1cc2c(=O)n(O)c(=O)[nH]c2cc1Cl)c1ccccc1 +CCC(CO)Nc1nc(NCc2ccc(C)s2)c2ncn(C(C)C)c2n1 +O=C(NCC(c1cnc(C2CC2)nc1)N1CCC(F)(F)CC1)c1c(F)cccc1Cl +O=C(O)c1cc(F)cc(C(=O)C=Cc2ccc(OCc3ccc4ccccc4n3)cc2)c1O +Cc1c(C(=O)OC(C)C(=O)N(C)Cc2ccccc2)oc2ccccc12 +Cc1ccc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1C +O=C(OCC1C(O)C(O)C(O)C2NC(=O)c3c(cc4c(c3O)OCO4)C12)c1ccccc1 +CC(C)(C)N(CCC(=O)c1ccc(Cl)cc1)Cc1ccccc1 +Cc1cccc2[nH]nc(NCC3CCC(NC(=O)c4cc(C(F)(F)F)ccc4Cl)CC3)c12 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+CC(C)N(C(=O)CN1C(=O)C(NC(=O)Nc2ccccc2)C(=O)N(c2ccccc2)c2ccccc21)c1ccccc1 +CC(C)(CN)COc1cc(F)cc2ccc(-c3nnc4ccccn34)nc12 +Cc1cc(=O)oc2cc(OC3OC(CO)C(O)C(O)C3O)ccc12 +C=CC(=O)Nc1cccc(CNc2nc(Nc3cn(C)nc3C)ncc2Cl)c1 +N#Cc1ccc(-c2ccc(C(=O)N3CCN(c4ncccn4)CC3)cc2)cc1 +CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccc(Cl)cc1n2CC#CCF +O=C(O)c1cccc(NC(=O)c2[nH]c(C3CCCC3)nc2CCC23CC4CC(CC(C4)C2)C3)c1 +O=C(NO)c1cnc(N2CC3C(C2)C3Nc2ccc3ccccc3n2)nc1 +CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2Cl)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 +COc1ccc(-c2noc3c2C(=O)c2cnccc2C3=O)cc1 +NS(=O)(=O)c1ccc(NCc2coc3ccccc3c2=O)cc1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc(Cl)c2)n1 +CCOc1ccc(C(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)cc1N(CC(C)C)C(=O)C(C)(C)C +COCCOCC#Cc1cc(-c2n[nH]c3c2C(=O)c2cc(CN4CCN(C)CC4)ccc2-3)cs1 +CCCN(CC1CC1)c1cc(C)nc(N(CC)c2ccc(C(C)C)cc2Br)n1 +CC(C)N(CC(O)c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc(CNC(=O)c2cccc3[nH]cnc23)cc1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(C#N)c(F)c1 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+Clc1ccc(-c2nn(-c3ccccc3)c3c2CCCC3)cc1 +O=C(O)Cc1ccc2oc(-c3ccc(C=CC(=O)Nc4ccc(Cl)c(Cl)c4)cc3F)nc2c1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccc(C(F)(F)F)cc4)oc3C)ccc21 +COc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(C2=NCCS2)cc1 +Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Br)c(Cl)c1 +CCN(CC)c1nc(C)nc2c(-c3cnc(OC)cc3C)c(C)nn12 +[O-][n+]1nc2c(-c3ccc[nH]3)cnn2c2cc(-c3ccsc3)ccc21 +O=C(O)c1ccc(NC(=O)C2NC3(CCCCC3)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)o1 +O=P(O)(O)OC1COCC1OC1OC(CO)C(OP(=O)(O)O)C(OP(=O)(O)O)C1O +COC(=O)C(C)NC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)CC(C)C)C(C)C +[H]C([H])([H])Oc1cc(F)cc(N(CCN)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CN(C)NC(=N)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)cc1 +CCCN(CC1CC1)c1cc(C)nc(C(=O)c2c(OC)cc(OC)cc2OC)n1 +Cc1ccccc1CN1CCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C1 +O=C(Nc1ccc(-c2nc(N3CCOCC3)c3ncccc3n2)cc1)Nc1cccnc1 +CC(C)Nc1nc(S(=O)(=O)c2ccc(N)nc2)ccc1-c1ccc(C(C)(O)C(F)(F)F)cn1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCCN(Cc2cccc3c2OCC3)C1 +Cc1csc(N(C)C2CCc3c(c4cc(F)ccc4n3CC(=O)O)C2)n1 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+CC(C)(C)n1nc(-c2ccc3nc(OC4CC4)ccc3c2)c(C(N)=O)c1N +Cc1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC3)n2)sn1 +CC(=O)SC(C(=O)c1ccc(Br)cc1)C(C)C(=O)N1CCCC1C(=O)O +Cc1cc2c(c(Oc3cc(NS(=O)(=O)c4ccc(Cl)cc4)ccc3F)n1)C(=O)N(C(C)C)C2=O +COc1cc(C(=O)NC2CCN(C)CC2F)c(F)cc1Nc1ncc(Cl)c(Oc2cccc3c2C(=O)N(OC)C3)n1 +CC(OCc1ccc(-c2ccccc2)cc1)(C(=O)NO)C(O)c1ncco1 +N=C(N)c1cccc(CN2CCC(NS(=O)(=O)c3ccc4nc(N)ccc4c3)C2=O)c1 +CC(C)Oc1ccccc1N1CCN(Cc2nc(CN3C(=O)CC4(CCCC4)CC3=O)co2)CC1 +CC#CCOc1ccc(S(=O)(=O)C(CCCCCC)C(=O)NO)cc1 +Cc1c(C(C)c2c(F)cccc2F)nc(N2CCCCCC2)[nH]c1=O +COc1ncc(Nc2ncc(C(C)(C)N3CCN(S(C)(=O)=O)CC3)cc2-c2nc(C)nc(N)n2)cc1F +COc1ccc(N2CC(CN3CCC(c4ccc5c(c4)OCO5)CC3)OC2=O)cc1 +CC(CO)(NC(=O)c1ccc(-c2ccccc2)cc1)C(=O)NO +[C-]#[N+]C1=C(C)N=C(C)C(C#N)C1c1cc2c(N)nccc2o1 +O=C(c1ccc(-c2ccncc2)cc1)N1CC2CNCC(C2)C1 +CN1CCN(C(=O)C=CC=Cc2ccc3c(c2)OCO3)CC1 +CCCC(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CC(=O)N1CCOCC1)CC1CCCC1 +CC(C)Nc1ncc2c(-c3ccccc3)nn(CC3CCC(N)CC3)c2n1 +CN1c2cc(C=CC(=O)NO)ccc2NC1CCc1ccccc1 +Cn1c(OC2CCN(Cc3ccccc3)CC2)nc(-c2ccncn2)cc1=O +CC1CC(N)CC(c2ccncc2NC(=O)c2csc(-c3c(F)cc(O)cc3F)n2)C1 +COc1cc(Nc2ccc(S(=O)(=O)NCC3CCCO3)c(F)c2)cc(OC)c1 +CN1C(=O)NS(=O)(=O)c2cc(-c3cnc(N4CCOCC4)c4nc(C=Cc5ccc6ccccc6n5)cn34)ccc21 +CSc1ccc(C2CN(C)Cc3cc(OCCCN4CCOCC4)ccc32)cc1 +Cc1nc(NCc2ccc(F)c(F)c2)nc(-n2ccnc2C)c1[N+](=O)[O-] +C=CC(=O)N1CCC2(CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)CC1 +O=C(CCCCCN1CCN(c2nc3ccccc3[nH]2)CC1)c1ccccc1O +O=C1NC(=O)c2c1c1c3ccccc3ccc1c1c2c2cccc3c2n1C(CO)CC3 +O=C1OC2(CCC(CNc3cnn(-c4ccccc4F)c3)CC2)CN1c1cnccn1 +CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(C(N)=O)cc2)c([N+](=O)[O-])c1 +O=C(CSc1nnccc1-c1cccc2ccccc12)Nc1ccccc1F +CN(C)CCOc1cc(C(N)=O)c2ncnc(NCc3cccc(NC(=O)c4ccnc(N5CCCC5)c4)c3)c2c1 +Cn1ccc2c(CCNS(=O)(=O)c3ccc(C=CC(=O)NO)cc3)cccc21 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cc(Cl)c(F)cc3F)ccc2[nH]1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1)S(=O)(=O)CC1CC1 +CCN(c1nc(C)nc(N(CCOC)CC2CC2)n1)c1c(C)cc(C)cc1C +CCOc1ccc(C#Cc2ccc(CC(C)NC(=O)N(C)CC)cc2)cc1 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+O=C(Nc1cc(F)c(CC(=O)N2CC(F)CC2COC2CCC(C(=O)O)CC2)cc1Cl)c1nccc2ccccc12 +O=C1Nc2cccc3c2C1(CCCCN1CC=C(c2ccccc2)CC1)CCC3 +CCc1c2ccccc2[n+](C)c2c1[nH]c1ccccc12 +O=C(Nc1ccc(CC(NC(=O)C23CC4CC(CC(C4)C2)C3)C(=O)O)cc1)c1ccnc2ccccc12 +CC(C)(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCC4CCN(c5ccc(C(F)(F)F)cn5)CC4)cc3)oc12 +O=C(NCc1cccs1)c1cc(C(=O)c2c(Cl)cccc2Cl)c[nH]1 +COc1cc(CCNCc2ccc(F)cc2F)ccc1NC(=O)Nc1cnc(C#N)cn1 +COc1cc(CNC(=S)NCc2ccc(C(C)(C)C)cc2)c(I)cc1O +Cc1ccc2c(CC(=O)O)cn(-c3ccc(C(F)(F)F)cc3CN(CC3CC3)C(=O)C3CC3)c2n1 +Cc1ccccc1-n1nc(-c2c(-c3ccc(F)cc3)nn3c2NCC(CO)C3)ccc1=O +CC1(C)CC(CCNc2ccc(OC(F)(F)F)cc2)(c2ccccc2)CCO1 +CNc1nc2nc(SCc3cccc(F)c3F)nc(NC(C)CO)c2s1 +O=C1c2c(O)cccc2Cc2cc(Cc3ccc(O)cc3)cc(O)c21 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)NC(CCC(=O)O)C(N)=O)cc1 +NS(=O)(=O)c1cc(S(=O)(=O)c2cccc(O)c2)cs1 +CC(C)N1CCN(c2cc(N3CCOCC3)cn3c(=O)c(O)c(-c4ncc(Cc5ccc(F)cc5)[nH]4)nc23)C1=O +Cc1ccc(C(=O)O)c(Oc2nc(Oc3cc(-c4cccc(CN)c4)ccc3N)c(F)cc2F)c1 +Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc2c(c1)OCC2CC(=O)O +N#Cc1cnc2c(F)cc(NCc3c[nH]cn3)cc2c1Nc1ccc(F)c(Cl)c1 +O=C(NCc1cc(Cl)ccc1Cl)c1cncc2nnc(-c3ccc(OC(F)F)cc3)n12 +CC1COCCN1c1cc(C2(S(=O)(=O)CCCO)CC2)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 +CCCCCCCCCC=C1CC(CO)(COC(=O)CC(C)C)OC1=O +Clc1ccc(C2CC(NCc3ccccc3)c3ccccc32)cc1Cl +COc1cc(OC)cc(C(=O)OCc2ccc3nc(N)nc(N)c3c2)c1 +Nc1nc2c(cnn2CCN2CCN(c3ccc(OCCO)cc3)CC2)c2nc(-c3ccco3)nn12 +Cc1ccc(C(=O)NC2CC2)cc1Oc1nnc(C)c2c1cnn2-c1ccc(F)cc1 +Cc1nc2c3c(c(C(=O)N4CCC4)cn2c1C)CCC1(CCc2ccccc21)O3 +Cc1cccc(C2N(CC(=O)O)C(=O)CC(c3cccc(Cl)c3)C23C(=O)Nc2cc(Cl)ccc23)c1 +CCCCN(C)Cc1c(C(F)(F)F)nc2n(-c3c(C)cc(C)cc3C)c(Cl)cn12 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(NCC3CCCCO3)nc12 +Cc1ccc2cc(Cn3cc(C(=O)NCc4c(C)cc(N)nc4C)nn3)cnc2c1 +NC(Cc1ccc(S(N)(=O)=O)cc1)C(=O)N1Cc2ccccc2CC1c1nc(-c2ccccc2)c[nH]1 +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)NN4CCN(C)CC4)cccc2-3)cc1 +CC(C)=CCCC(C)=CCCN(C)CCOP(=O)(O)OP(=O)(O)O +CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(C#N)cc3)c2)c2cnc(N)nc21 +Cc1cc(NC(=O)c2cccc(CN3CCCC3)c2)nn1Cc1cc(Cl)ccc1OCC(C)C +CCCCCCCN(CCCCCSc1nc(C2CCCCC2)c(C2CCCCC2)[nH]1)C(=O)Nc1ccc(F)cc1F +CCOC(=O)c1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 +CC(c1ccc(O)cc1)C(O)C=CC1C2CCC(O2)C1CC=CCCCC(=O)O +CC(C)CNC(=O)CC1Sc2sc(S(N)(=O)=O)cc2NC1=O +Cc1nc(NC2COCC2C)nc(-n2ccnc2C)c1[N+](=O)[O-] +COc1ccc2c(c1)c(CC(=O)NCc1ccncc1)c(C)n2C(=O)c1ccc(Cl)cc1 +COc1ccc2c(c1)CNC(C(=O)N1CCCC1C#N)C2 +O=C1OC2(CCN(C(=O)Nc3cc(-c4ccccc4)n[nH]3)CC2)c2ccccc21 +CNC(=O)CN1CCN(c2cc(C)c3nc(-c4c(NCC(O)c5cccc(Cl)c5)cc[nH]c4=O)[nH]c3c2)CC1 +CN(CCN(C)c1nc2ccc(Br)cc2s1)c1nc2ccc(Br)cc2s1 +CCCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NC(CC(=O)O)C(=O)O +CN(C)CC(OC(=O)N1Cc2c(n[nH]c2Nc2ccnc(C(F)(F)F)n2)C1(C)C)c1ccccc1 +CNC(=O)c1cc2c(Oc3ccc(C(=O)NCCN4CCOCC4)cc3)cncc2s1 +Cc1c(-c2cnc(N)c(-c3ccc(C(=O)NC(CO)c4cccc(C(F)F)c4)c(F)c3)c2)cnn1C(F)F +CN(CCCNCc1ccc(C(=O)O)cc1)CC(=O)Nc1ccc(Oc2ccccc2)cc1 +O=C(c1cccnc1)N1CCC(c2nc(-c3cnc(-c4ccccc4)nc3)c[nH]2)CC1 +Cc1cccc(C)c1C1CCN(CCC(=O)N2c3ccccc3CC2C(=O)N(C)C)CC1 +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)Nc3ccccc3O)nc12 +Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OC(C)C(F)(F)F)c(C3CCC3)cn2)no1 +CC12CCC(O)CC1CCC1C2=C(O)C(=O)C2(C)C(c3ccc(=O)oc3)CCC12O +CCCS(=O)(=O)c1ccc2cc(-c3cccc(-c4ccccc4)c3)[nH]c2c1 +O=C(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)c1ccccc1 +CCN(CC)c1ccc2nc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1 +Oc1ccc(CC2Sc3cc(O)ccc3OC2c2ccc(OCCN3CCCCC3)cc2)cc1 +N#Cc1ccc(Nc2nc(C#N)nc(NC3CCCCC3)n2)cc1 +COc1ccc(C(=O)Nc2ccc(-c3ccc(OC4CCN(C)CC4)cc3)cc2)cc1-c1cccc(Cl)c1 +CCCN(CC1CC1)c1nc(C)nc2c1sc(=S)n2-c1c(C)cc(C)cc1C +O=C(CCCCN1CCC(c2ccccc2)CC1)c1nc2ccccc2s1 +CCOP1(=O)N=C(C2=C(O)C(C(C)(C)C)N(CCC(C)C)C2=O)Nc2ccc(NS(C)(=O)=O)cc21 +Cc1cc(F)ccc1Oc1cc(C(C)(C)C)ccc1C(=O)Nc1ccc(C(=O)O)nc1 +CCCCN1CC2CCC(OCc3ccccc3)C1CN2Cc1ccccc1 +COc1ccc2c(c1)CCC(CCN1CCN(c3ccccc3)CC1)C2 +Cc1cccc(C#Cc2ccc(N3CC(C)(C)N(C)C3=O)nn2)c1 +N=C(N)c1cc2[nH]c(-c3cccc(OCC4CCCNC4)c3O)nc2cc1F +COc1ncc(C(=O)NC2(C(=O)NC(C)c3ncc(-c4cc(Cl)cc(F)c4-c4noc(C)n4)cc3F)COC2)cn1 +Cc1cc(C)n(Cc2ccc(Cn3cc(C(=O)NCc4c(C)cc(N)nc4C)cn3)cc2)n1 +Cc1cccc2c1N(C1CCN(S(=O)(=O)c3cccc4ccccc34)CC1)C(=O)OC2 +COc1ccc(CNC(=O)CCCCC=CCCCCCCCCCCCCC(=O)NCc2ccc(OC)c(O)c2)cc1O +CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC(C)(O)C3)c(Cc3ccccc3C(F)(F)F)sc21 +CCC(=NNC(N)=S)c1cccc([N+](=O)[O-])c1 +CCC(C)Oc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc2[nH]cnc12 +CN1CCCN(CCCOc2ccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)cc2Cl)CC1 +COc1ccc(-c2nc3c(c(=O)[nH]2)COCC3)cc1 +CCCCc1nc2ccc(C3CC4CCC(C)(C)N4O3)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(C(F)(F)F)n2)c2c(N)ncnc21 +CC(=O)c1ccc(N2CCN(Cc3cccnc3)CC2)cc1 +O=C(NCc1ccc(F)c(F)c1)c1cc2cccc(O)c2n(O)c1=O +COc1ccc(N2CCN(C(=O)C3CCCCC3C(=O)NCC#N)CC2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccccc1)c1ccc(CNS(C)(=O)=O)c(F)c1 +CCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OCC(C)C(=O)OC)S(=O)(=O)c1ccc(OC)cc1 +O=S(=O)(NCC(c1ccc(C(F)(F)F)cc1)N1CCN(CC(O)COc2ccc(F)cc2)CC1)c1ccccc1Cl +CN1CCC23c4c5ccc(O)c4OC2C(O)C=CC3C1C5 +CC(=NNC(=O)c1ccccc1)C(Cl)=NNc1ccc(S(N)(=O)=O)cc1 +O=C(Nc1ccc(F)cc1F)NC(Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1 +O=C(O)CCC(=O)Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1 +O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(N2CCc3c(cnc4ccccc34)C2)c1 +COc1ccc(NC(=O)Nc2cccc(C=CC(=O)CC3OC(CO)C(O)C(O)C3O)c2)c([N+](=O)[O-])c1 +COc1cccc(-c2cn(Cc3c(F)cccc3S(=O)(=O)C(C)C)c(=O)n(CC(N)c3ccccc3)c2=O)c1F +N=C(N)c1ccc(CNC(=O)CN2C(=O)C(NS(=O)(=O)Cc3ccccc3)CSc3ccccc32)cc1 +CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1NC1CCC(C)(O)CC1 +Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cnc4ncccn34)n2)cc1 +CNC(=O)Cn1cc(-c2cnc3ccc(N(CCO)c4cc(OC)cc(OC)c4)cc3n2)cn1 +COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cn1 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCc3c(C(=O)O)nc(C)n3-c3ccccc32)n1 +COc1cc(OC)c(-c2cc3ccccc3s2)cc1C=CC(=O)c1ccc(C(=O)O)cc1 +O=c1[nH]cnc2c(C3OC(CO)C(O)C3O)n[nH]c12 +CCN(CC)CCNc1ccc(CNS(C)(=O)=O)c2sc3ccc(O)cc3c(=O)c12 +Cc1cc(F)c(F)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CC(C)N(C(=O)c1ccc2ccccc2c1)C1CCNC1 +CCN(CC)CCCNC(=O)c1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(-c3ccccc3)no2)n1 +CCCCCCCCCCCNC(=O)C(N)CCC(=O)NC(CCCC(N)C(=O)O)C(=O)O +COc1cccc2c1CCCC2CN(C)CCc1ccc2ccoc2c1 +CC(C)(C)C(=O)Oc1coc(CSc2nc3cc(C(=O)O)ccc3o2)cc1=O +Cc1cc(Nc2cc(C)c(C#N)c(NCCOc3ccccc3F)n2)n[nH]1 +Cc1ccccc1N1CCN(C(=O)c2ccc(F)cc2Cl)CC1=O +Nc1nc(N)c2c(Cl)c(NC(=O)Cc3ccc(Br)cc3)ccc2n1 +NC1(Cc2cccc(Cl)c2)CCN(c2ncnc3[nH]ccc23)CC1 +O=C(C[n+]1ccn2cccc2c1-c1ccccc1)c1ccccc1 +O=C(O)C=Cc1ccc2c(c1)c(CCc1ccccc1)cn2-c1ccccc1 +COc1ccc(Br)c(Cn2cc(CCCCC(=O)NO)nn2)c1 +CCC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 +COc1cc(-c2cn(CC(=O)Nc3cccc(F)c3F)nn2)ccc1-n1cnc(C)c1 +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OC[Si](C)(C)c2ccccc2C)c1 +CCCC(CCC)n1cc2c3c(nc(C)nc31)N(c1ccc(C#N)cc1C)CC2 +O=C(NCCCN1CCCC1)c1ccc(C=C2CCCn3c2nc2cc(Cl)ccc2c3=O)cc1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(I)cc1-c1cn[nH]c1 +CC1(C)CC1COc1cc(C(F)(F)F)ccc1C(=O)Nc1cc[nH]c(=O)c1 +Cc1n[nH]c2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)cc3)cc12 +NCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1 +Cc1c(S(=O)(=O)Nc2ccc3nccc(N4CC(C)NCC4C)c3c2)sc2ccc(Cl)cc12 +O=C(O)c1cccc(S(=O)(=O)N2CCc3ccc(F)cc3C2)c1 +CC(C)n1c(-c2ccnc(N)n2)cc2c1CCNC2=O +CCn1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)c(C#N)c2ccc(OC(F)F)cc21 +CCN1CCC(c2ccc(C(=O)Nc3cc(Oc4cc5ccn(C(=O)NC)c5cc4OCCCF)ccn3)cc2)CC1 +CNC(C)C(=O)NC1CCCC2CC3CCN(CCc4ccccc4F)CC3N2C1=O +Cc1oc(-c2cccc(-c3ccn[nH]3)c2)nc1C(=O)N(CC(=O)O)Cc1nc2ccccc2s1 +C#CCN1CCN(c2c(Cl)cccc2NC(=O)c2ccc(Br)o2)CC1 +COc1ccc2c(c1OCCNCC1COc3ccccc3O1)CCCC2 +O=C(Nc1ccc(CO)cc1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=C(NC1C2CC3CC(C2)CC1C3)C1CCCN1Cc1ccc(Cl)cc1 +CC1CN(c2ccc(Nc3ncc4c5cc[nH]c(=O)c5n(C5CCCC5)c4n3)nn2)CCN1 +CCOCn1nnc(-c2ccc(F)cc2)c1-c1ccnc(Oc2cccc(NC(C)=O)c2)n1 +Cc1nc(-c2cnn(C)c2-c2ccc(Cl)cc2C#N)c2c(N3CCC3)ncnn12 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(CO)CC4)cc2)CC3)cc1 +CCCC(CCC)C1=C(Br)c2nc3ccccn3c2C(=O)C1=O +Cc1cc(C)c(CN2CCc3ccc(OC4CCOC4)c(Cl)c3C2=O)c(=O)[nH]1 +COC(=O)CN(Cc1ccccc1OC)CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(c2ccccc2)CC1 +CCCOC(=O)NC1CCN(C(=O)OC2C3CC4CC(C3)CC2C4)C1 +N=C(Nc1ccc2ccn(CCN3CCCCC3)c2c1)c1cccs1 +Cc1ccc(C(C)(O)c2ccnc(Nc3ccc(C#N)cc3)n2)cc1 +O=C(NCCc1ccccc1)NC1C2CC3CC(C2)CC1C3 +Cc1c(C(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CN(C)CC4)c2)nnn1-c1nonc1N +CCOC(=O)c1nnc2n1CCN(C(=O)CC(N)Cc1cc(F)ccc1F)C2 +Nc1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2nc(CCCCc3ccc(F)cc3)sc2n1 +C=C1CCC2C(C)(C)CCCC2(C)C1CCC(C)=CCn1c[n+](C)c2nc[n-]c(=NOC)c21 +CCOC(=O)C1CCc2c(sc3ncnc(Nc4cc5sc(=O)[nH]c5cc4OC)c23)C1 +O=C(NCc1cccc(O)c1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 +CC(C)C(=O)Nc1ccc(F)c(C2(C)N=C(N)N(C)C(=O)C2(C)C)c1 +COc1ccc(CNc2nc(-c3ccccc3)c(Cc3ccccc3OC)s2)cc1 +COc1cc2ncnc(N3CCN(C(S)=Nc4ccc(Cl)c([N+](=O)[O-])c4)CC3)c2cc1OC +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)CCc1ccccc1)C2 +O=C(NC(Cc1ccccc1)C(=O)NC(C=C[N+](=O)[O-])CCc1ccccc1)OCc1ccccc1 +C[Si](C)(C)CCOCOc1cc(C(F)(F)F)ccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(S(=O)(=O)NCCCN4CCCC4)cc3)nnc2c1 +CNC(=O)N1C(=O)N(c2cncc(Cl)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1S(C)(=O)=O +CC12CCC3C4CCC(=O)C=C4CCC3C1CCC21CCCO1 +CC1(C)C2CC=C(C[N+](C)(C)Cc3ccc(-c4ccccc4Cl)cc3)C1C2 +O=C(OCCCCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)c1ccc(O)cc1O +COc1cc(C)c(-c2nc3ccc(C(=O)Nc4ccc(C)c(C)c4)cc3[nH]2)c(C)c1 +Cc1cc(C)cc(Nc2nccc(-n3cc(C)c(CN4CC(O)C4)c3)n2)c1 +COc1nc(-c2nc3n(n2)CCCC3c2cc(C(C)(C)C#N)ccc2Cl)ccc1-n1cnc(C)c1 +CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(F)nc3)cc2s1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2ccc(Cn3ccc(=O)[nH]3)cc2)c1 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccn1)CC2 +O=c1[nH]c2ccc(O)c(-c3ccc(S(=O)(=O)NCCBr)cc3)c2c2ccsc12 +O=c1[nH]c2c(C(F)(F)F)cccc2c(=O)n1CCCCCn1ccnc1 +COc1cc2c(NC3CCN(C(C)C)CC3)nc(N3CCCN(C(C)C)CC3)nc2cc1OCCCN1CCCC1 +CC1C(=O)NCC1C(=O)Nc1cc(-c2cccc(OC(F)(F)F)c2)n(-c2cccc(F)c2)n1 +CN1C2CCCC1CC(NC(=O)n1c(=O)[nH]c3ccccc31)C2 +CCOP(=O)(O)c1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 +CN1C2COCC1CC(NC(=O)c1cn(-c3cnccn3)c3ccccc13)C2 +CCc1c(-c2nsc(-c3ccc(CC(C)C)c(C#N)c3)n2)ccnc1CCCC(=O)O +CC(C)C#Cc1csc2c(NCC(N)Cc3ccccc3)nc(-c3ccncc3)nc12 +O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c2c1OC1(CCSCC1)O2 +CC(Cc1ccc(Cl)cc1)S(=O)(=O)Nc1ccccc1S(N)(=O)=O +O=S(=O)(Nc1cncc(-c2cnc3ccccn23)c1)c1ccc(F)cc1 +CS(=O)(=O)n1cc2c(n1)CN(C1CC(N)C(c3cc(F)ccc3F)N(CCO)C1)C2 +CC(C)(C(=O)Nc1cnc2ccccc2c1)S(=O)(=O)c1ccc(F)cc1 +CC(C)N1C(=O)C2(N=C1N)c1cc(C#CC3CC3)ccc1CC21CCC(OC(F)F)CC1 +O=C(O)CN1C(=O)C(=O)N(Cc2nc3cc(Cl)ccc3s2)C1=O +CCCCCCCCS(=O)(=O)NCCCN(CCCNCCCCNCCCN)CCCNS(=O)(=O)CCCCCCCC +COc1ccc(NCC(C)NC(=O)C2(Nc3cccc(-c4ccccc4)c3)CCCCC2)cc1 +CCN(Cc1cccc(OC)c1)C(=O)Nc1ccc(-c2cn[nH]c2)cc1OC1CCN(C)C1 +CC(C)(CC(O)(Cc1cc2ccncc2[nH]1)C(F)(F)F)c1cc(-c2ccccc2)ccc1O +COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(C(C)C)cc1 +CC(C)C1CN(CCN2CCCC2)C(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1 +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CCCC2CN2CCN(CC(=O)O)CC2)cc1 +Cc1cc(C=CC#N)cc(C)c1Oc1nc(NC2CCN(Cc3cccc(F)c3)CC2)nc2ccsc12 +Cc1cc(N)nc(C)c1CNC(=O)c1cn(Cc2ccc(-n3cccn3)cc2)cn1 +COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2C(=O)N(C)C3)n1 +NCCCCC(C(=O)NCc1cccc2ccccc12)N1Cc2[nH]c3ccccc3c2CC(NC(=O)Cc2ccccc2)C1=O +N#Cc1ccc(-c2scc3c2C2(CCN(Cc4ccccc4)CC2)OC3=O)cc1 +C=CC(=O)N1CC(C2(C)CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)C1 +CCOc1cccc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)c1 +Cc1cc(N2CCN(c3ncccn3)CC2)nc2ccc(NC(=O)C3CCC(C)CC3)cc12 +O=[N+]([O-])c1ccc(-c2cncc(C3CC4CCC3N4)c2)cc1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1ccc(F)c(F)c1 +O=C(O)c1cccc(C(CC(=O)c2ccc(F)cc2)CC(=O)c2ccc(Cl)cc2)c1 +CCC(C)(CC)NC1=NCCNC(c2ccc(C)cc2)=C1 +O=S(=O)(Oc1ccc(-c2c[nH]c(SCCc3c[nH]cn3)n2)cc1)c1ccccc1 +CCC1CN(c2c(NC(=O)c3nc(-c4c(F)cccc4F)sc3N)cnn2C)CCC1(CN)OC +Nc1ncc(-c2cc(N3CCC3)nc(N3CC4CC3C4)n2)cc1OC(F)F +CCC(NC(=O)c1cc(C(=O)NC(CC)c2cccnc2OC)n2c1COCC2)c1ccccc1 +CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCCc1ccc(O)cc1 +OCC1C(O)C(O)C(O)CN1CCCCCCOc1cc(F)ccc1F +N#Cc1cccc(NC(=O)N(CCN2CCC(O)C2)C2CCC3(c4cccc(C#N)c4)CC3C2)c1 +CNC(=O)c1cc(F)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1nc2cccnc2n2c(-c3cc(OC4CCC(F)(F)CC4)ccc3Cl)nnc12 +Cc1cc(I)cc(C)c1Oc1ccc(N)c(Nc2ccc(C#N)cc2)n1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C=NOC(C)(C)C)cc2n1Cc1ccccc1 +C[N+](C)(CC#CCOC1=NOCC1)CCCCCCNC(=O)c1cn(Cc2ccccc2)c2cc(Br)ccc2c1=O +Cc1nc(-c2cn3c(n2)-c2cc(C(C)N4CCN(C(C)(C)C)CC4)c(F)cc2OCC3)n(C(C)C)n1 +COc1ccc(C2C(C(=O)O)C(c3ccc4c(c3)OCO4)CN2CC(=O)Nc2ccc(C)c(C)c2)cc1 +CN(C(=O)Cn1c(=O)oc2ccc(N(C)c3ccccc3)cc21)c1ccccc1 +O=C1NCCc2[nH]c(-c3ccnc(-c4cc5ccccc5s4)c3)cc21 +CNCc1nccn1-c1ccc(N2CCC(NS(=O)(=O)C=Cc3ccc(Cl)s3)C2=O)c(F)c1 +CNC(=O)c1ccc2cc1Nc1nc(ncc1Cl)Nc1ccc(N3CCN(C)CC3)c(c1)CC2 +O=C(NCc1ccc(N2C3CCCC2CC3)cc1Cl)Nc1cccc2[nH]ncc12 +O=C1COC(c2ccc(C=Cc3cccc(Cl)c3)cc2)=NN1 +CN(C)CCCn1nc(Nc2c(Cl)cccc2Cl)c2cnc(Nc3ccccc3)nc21 +CON=C(C)c1ccc(-n2ccnc2)c(NC(=O)c2cncc(-c3ccccc3)n2)c1 +COc1cccc(COc2ccnc(Nc3ccc(C#N)cc3)n2)c1 +Cc1c(COc2ccccc2-c2cccc(N3CCC4(C(=O)O)CC4C3)n2)ccc2c1CCN(C1CCC1)C2 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2F)nc1-c1ccccc1 +CN1CCN(c2ccc(-c3cnc4c(-c5ccnc(Cl)c5)cnn4c3)cc2)CC1 +CCC(C(=O)NO)N(CC(C)C)S(=O)(=O)c1ccc(OC)cc1 +COc1cc2ccnc(Cc3ccc(OC)c(OCCF)c3)c2cc1OC +CC(N=O)c1ccc2nnc(C(C)c3c(F)cc4ncccc4c3F)n2n1 +CCOC(=O)C(C)NP(=O)(COCCOc1cc(N)nc(N)n1)NC(C)C(=O)OCC +Cc1cc(N2CCN(c3ccnc(CO)n3)CC2)nc(C)n1 +CC1=C(C(=O)Nc2ccc(Cl)c(C(=O)OC(C)C)c2)SCCO1 +CCC(NP(=O)(O)CNC(=O)OCc1ccccc1)C(=O)NC(CC(C)C)C(=O)O +O=C(O)CCc1cc(CCCS(=O)(=O)c2ccccc2)cc(Cc2cccnc2)c1 +COc1ccc(CC2(C(=O)NC(Cc3ccc(NC(=O)c4c(Cl)cccc4Cl)cc3)C(=O)O)CCCC2)cc1 +CCCc1ccc(S(=O)(=O)NCC2CCCN2c2nc(NCc3csc(-c4ccccc4)n3)nc(NC3CC3)n2)cc1 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(Cl)c2[nH]1 +Cn1cc2c(nc(NC(=O)NC3CCN(C(=O)NCCCc4ccccc4)CC3)n3nc(-c4ccco4)nc23)n1 +CN(C)CCCNc1cc(-c2ccc(CN3CCN(C)CC3)cc2)nc2ccccc12 +CC(Nc1ncnc2[nH]c(-c3ccc(O)cc3)cc12)c1ccc(F)cc1 +COCCNC(=O)c1c(NC(=O)C2CCCN2C(=O)C2CC2)sc2c1CCCC2 +CN1CCC=C(c2nsnc2SCCCCCCCCSc2nsnc2C2=CCCN(C)C2)C1 +CC#CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CC(=O)c1cccc3c1OCO3)c(=O)n2C +CCCSc1c(C(=O)N(C)C2CCCCC2)cnn1-c1ccc(C(=O)O)cc1 +Cc1ccc(S(=O)(=O)NCCCCN2CCN(c3cccc(NS(=O)(=O)C(C)C)c3)CC2)cc1 +Cn1nc(OCc2c(-c3ccc(F)cc3)nnn2C)cc1C(=O)NC1CCOCC1 +Cc1ccc(N(C(=O)NCCCN2CCC3(CCc4ccccc43)CC2)c2ccc(F)cc2)cc1 +CN(C(=O)c1ccc(Cn2cccn2)cc1)C1CCN(C2CCC2)C1 +COc1cc2c(=O)n(Cc3ccc4c(c3)OCO4)cnc2c(OC)c1OC +O=C(O)C1=Cc2cc(C(F)(F)F)ccc2OC1C(F)(F)F +CCCCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC +O=c1[nH]nc2c3c([nH]c4cccc1c43)CN(C1CCCCC1)C2 +COCC(C)NC(=O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12 +Cn1c(CN2CCC(c3cccc(C(F)(F)F)c3)CC2)nc2ccccc21 +O=C(Nc1cnccc1Br)c1cccc(-c2ccc3ccccc3c2)c1 +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5ccccc5F)no4)cc3)cc2)C(=O)NC(=O)NC1=O +CC12CCC3C(C(SCc4ccccc4)CC4=CC(=O)CCC43C)C1CCC2=O +O=C(NS(=O)(=O)c1cccc(Br)c1)c1ccc(Cl)cc1Cl +CC1CCCN1c1cccc(Nc2cc(-c3cccc(C(N)=O)c3)nn3ccnc23)n1 +CN(C)CCCN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 +O=C(Nc1nc2ccc(C(F)(F)F)cc2s1)N1CCC(F)(c2ncc(CC(O)CO)cc2Cl)CC1 +COc1cccc(NC(=O)Nc2nc3nn(C)cc3c3nc(-c4ccco4)nn23)c1 +N#Cc1cccc(-c2cc(COCC3(c4ccccc4)CCNCC3)cc(C(F)(F)F)c2)c1 +O=C(O)c1ccc(Oc2ccc3c(c2)B(O)OC3)cc1 +CC(NC(=O)Nc1cc2[nH]nc(N)c2cn1)c1ccc(F)c(F)c1 +CCCCN(C)CCNC(=O)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 +Oc1ccccc1-c1nc(NC2CCNC2)c2ccccc2n1 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+CC(C)Oc1ncc(-c2nc(-c3cccc4c3OCCNC4CCCC(=O)O)no2)cc1Cl +O=S(=O)(NCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc(F)c(Cl)c1 +N#Cc1c(-c2ccccc2)nc(SCc2nc3ccccc3[nH]2)nc1N1CCNCC1 +O=C(O)c1csc(-n2nc(-c3ccc(F)c(F)c3)cc2O)n1 +Cc1cccc(Nc2ccccc2C(=O)NCCCCCC(=O)NCCCCCCCNc2c3c(nc4ccccc24)CCCC3)c1C +Clc1ccc(CC2CCN(CCC#Cc3c[nH]cn3)CC2)cc1 +NC(=NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1cccc(Br)c1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CCC1C2 +CC(C)(CNC(=O)N1CCOCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CCC(C3)N4CC(=O)N(C)C)cc12 +O=C1CC(c2ccc(N3CCOCC3)cc2)(c2ccsc2)NC(=O)C1Sc1ccccc1Cl +CCC1(C(=O)O)Cc2cc(OCCCOc3ccc(C(C)(C)C)cc3Cl)ccc2O1 +COCc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2cc(C)no2)cc1 +Nc1nc(NN=Cc2ccc(F)cc2)nc2c1ncn2C1OC(CO)C(O)C1O +C#Cc1ccc(C2CC3CCC(C2C(=O)OC)N3C)cc1 +OCC1C(O)C(O)C2CSC(=NCc3cccc(Cl)c3)N12 +CCc1nc(CC(C)C)c(C(N)=O)n1Cc1ccc2oc(-c3ccccc3NS(=O)(=O)C(F)(F)F)c(Br)c2c1 +CS(=O)(=O)c1ccc(-c2cscc2-c2ccc(F)cc2)cc1 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+CN(CC(O)Cn1c2ccccc2c2ccccc21)S(C)(=O)=O +NCc1ccc(CNC(=O)C2C(C(=O)Nc3ncc(Br)s3)C3C=CC2C32CC2)cc1 +CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4C)c2Cl)cc1 +c1cnc2ccc(Cc3nnc4ncc(-c5cnn(C6CCNCC6)c5)nn34)cc2c1 +CCN(c1cc(-c2ccc(CN3CC(F)C3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1 +O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)c(OCCCN3CCOCC3)cc2n1CCO +CC(OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1ccccc1 +O=C(NC1CN2CCC1CC2)c1cc2cc(F)ccc2s1 +COc1ccc(S(=O)(=O)N(C)c2nc3ccccc3c(=O)o2)cc1 +O=C(O)C1CN(Cc2ccc3c(c2)OCc2c-3noc2-c2onc(-c3ccccc3)c2C(F)(F)F)C1 +CC(C)CC(=O)NC1(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)COC1 +O=C(c1n[nH]c2c1CN(CC(F)(F)F)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 +C=C(c1ccc(N(C)C)c(C#N)c1)c1cc(OC)c(OC)c(OC)c1 +CC=C1C(=O)CC2C3CCC4=CC(=O)CCC4(C)C3CCC12C +CC(=O)Nc1nc2ccc(-c3ccc(N)nc3)cc2s1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(Cc3c(F)cccc3Cl)CC2)C1 +CC(C)CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1C(=O)N(C)N=Cc2ccccc21 +COc1nccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1Cl +COCC(NC(=O)Nc1cc2[nH]nc(NC(C)C(F)(F)F)c2cn1)c1ccccc1 +NC1=NC(c2cc(NCc3nn(C(F)F)cc3Cl)ccc2F)(C(F)F)C2CC2O1 +CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C(C)c2ccc(F)cc2)C1 +COc1ccc2c(c1)-c1nc(-c3ccccc3)[nH]c1CC2 +Cc1nnc2n1-c1ccc(C#CCN3C(=O)CSc4ccccc43)cc1C(c1ccccc1F)=NC2 +COc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)NCCCc3ccccc3)cc1)C2 +COc1cc(OC2CCN(C(C)=O)CC2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +O=c1c(NCCc2ccc(Oc3ccccc3)cc2)c(Nc2ccncc2)c1=O +CCc1cc(-c2ccccc2)cc(CC)[n+]1-c1ccc(S(N)(=O)=O)cc1 +CCCCCCC(C)(C)c1ccc(C2CCCC(O)C2)cc1 +CC1(C)C(=O)N(C(=O)NCC2CCN(CC3(O)CCOCC3)CC2)c2cc(F)ccc21 +Cn1ccc(-c2cc(S(=O)(=O)c3ccccc3)cc3c4c(oc23)CCNC4)n1 +CC(C)c1nc(-c2ccccc2)cc(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +COc1ccc2cc(C3C(O)C(=O)N3c3cc(OC)c(OC)c(OC)c3)ccc2c1 +N#Cc1c(-c2cccc(F)c2)c2c(=O)[nH]c(=O)[nH]c2[nH]c1=O +COc1ccc(-c2c[nH]c3ccc(-c4nnc(N)s4)cc23)nc1OC +Cc1cccc(Cl)c1-c1nc(CN2CCC(C(=O)NCCCN3CCC(C(C)C)CC3)CC2)c(C)o1 +COc1ccccc1C=C1Oc2ccc(F)cc2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +CN(C(=O)Cc1ccccc1)C1CC2(CCCO2)CCC1N1CCCC1 +CCN(c1cc(-c2ccc(CN3CCCNCC3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1cccs1 +COc1cc2c(cc1O)oc(=O)c1c2c(-c2ccc(O)cc2)c2c3cc(OC)c(O)cc3ccn21 +O=S(=O)(c1ccccc1)N(Cc1ccccc1OC(F)(F)F)c1cc2ccccc2s1 +CCCNCc1c(-c2ccccc2)c2cc([N+](=O)[O-])ccc2n1C +NC1=NC2(c3cc(-c4cccnc4F)ccc3Oc3c(F)cc([N+]4=CCOCC4)cc32)c2nccn21 +Cc1cccc(C)c1OCC(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)NC(=O)OC1COC2OCCC12 +Cn1c(N2CCCCC2)cc(OCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O +Cc1ccc2c(C3CCN(CCN4CCN(C(C)C)C4=O)CC3)cn(-c3cccc(C(F)(F)F)c3)c2c1 +Cc1cccc(NC(=O)c2cncc(N3CC4CNCC4C3)c2)c1 +CN(Cc1ccc(C(=O)O)cc1)CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1 +CCCCCCOP(=O)(O)C1=CC(OC(CC)CC)C(NC(C)=O)C(N)C1 +Nc1cnc(-c2ccc(C3CCC3)c(OCc3cccnn3)c2F)cn1 +O=c1sc2ccccc2n1CCCCN1CCN(Cc2ccccc2)CC1 +COc1ccc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)cc2F)c(F)c1 +COc1ccc(-n2[nH]c3c(cnc4ccc(Cl)cc43)c2=O)cc1 +O=C(O)C1(COc2ccc(-c3ccc(-c4ncc(C(F)(F)F)[nH]4)cn3)cc2)CCOCC1 +O=c1[nH]sc2c1c(=O)c1cc(F)c(-c3cccnc3)cc1n2C1CC1 +O=C(O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2Oc2ccccc2)cc1 +Cn1c(N2CCNC(c3ccc(Cl)c(Cl)c3)C2)nc(-c2ccncc2)cc1=O +CC(=O)Nc1ccc(C=CC(=O)N(C)Cc2cc3ccccc3n2C)cn1 +CCc1c(C)[nH]c(=O)c(-n2cccc2)c1Cc1cc(C)cc(C)c1 +Cc1cncn1CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCC3 +Cc1ccc(-c2ccccc2C=NNCCN2CCCC(C(=O)O)C2)cc1 +CCOC(=O)CC1OP(=O)(OCC2C=CC(n3cc(C)c(=O)[nH]c3=O)O2)Oc2cccc(Cl)c21 +CCCc1cc(-c2cncc(OCC(N)Cc3c[nH]c4ccccc34)c2)cc2c(C)n[nH]c12 +Oc1cc(-c2ccccc2)ccc1Cn1cncc1CNc1ccc(-c2nc3ccccc3s2)c(-c2ccccc2)c1 +CCOC1CC(C(=O)Nc2ccc(N3CCOCC3=O)cc2)N(C(=O)Nc2ccc(Cl)cc2)C1 +Cc1nn2c(N3CCN(C)CC3)cc(C(C)(C)C)nc2c1-c1ccccc1 +O=C(CC12CCC(C(=O)O)(CC1)CC2)N1CCc2c(n(Cc3ccc(Cl)cc3)c3ncccc23)C1 +COC(=O)Nc1ccc2c(c1)OCCCCCCC(NC(=O)C=Cc1cc(Cl)ccc1-n1cnnn1)c1nc-2c[nH]1 +O=C(NC(=O)c1c(F)cccc1Cl)NC1c2ccccc2-c2ccccc21 +O=C(Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)c(F)c1)c1ccccc1F +Cc1ccc(NN2C(=O)OC(C)(c3ccc(Oc4ccccc4)cc3)C2=O)cc1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c1cccc(NC(=O)OC(C)(C)C)c1 +Cc1cc(=O)c(Oc2ccc(Cl)cc2F)c(-c2ccc([S+](C)[O-])cc2)o1 +CN(Cc1cccc2c1S(=O)(=O)N=C2C1=C(O)C2(CC2)N(Cc2ccc(F)c(Cl)c2)C1=O)S(C)(=O)=O +COc1ccc(-n2c(CCN3C(=O)c4cccc(-c5ccncc5)c4C3=O)nc3ccccc3c2=O)cc1 +CN1CCCc2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)cc3n2C)C1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NCC(F)(F)F +O=C(c1ccc(-c2ccccc2)cc1)c1[nH]c2ccccc2c1Nc1nc(N2CCOCC2)ncc1[N+](=O)[O-] +O=C(NCCc1ccccc1)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cc1 +Cc1nocc1C(=O)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Cc1nc2ccccc2n1CC(=O)N1CCN(c2scnc2-c2nc3ccccc3[nH]2)CC1 +Cc1cccc(N=Nc2c(C)[nH]n(C(N)=S)c2=O)c1C +CCc1cc2cc(N3CC4(CN5CCC4CC5)OC3=O)ccc2s1 +CCOc1cc(CNC(C)C(O)c2ccccc2)cc(Cl)c1OCC +CN(C)c1ccc(-c2csc3c(=O)cc(N4CCOCC4)oc23)cc1 +Cc1cc(C(=O)Nc2cccc(Br)c2)nn1-c1cccc(C(F)(F)F)c1 +O=C(Nc1cc(Br)ccc1N1CCN(CCO)CC1)c1cc2ccccc2oc1=O +COc1ccc(-c2nnsc2-c2cc(OC)c(OC)c(OC)c2)cc1 +CN(CC(O)CO)C(=O)CN1C2C=C(c3[nH]c4nccc5c4c3CN(C)c3ccc(F)cc3-5)CC1CC2 +CN(C)C1CCN(c2ccc(NC(=O)CCCC(=O)c3ccc(Cl)cc3)cc2)C1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc2c(ccn2Cc2ccccc2C#N)c1 +CCCS(=O)(=O)Nc1ccc(F)c(-c2cc3cnc(N)nc3n(C)c2=O)c1F +Cn1cc(-c2ccc(C(F)(F)F)cc2-c2cn[nH]c2)c2ccc(S(=O)(=O)Nc3ncns3)cc21 +CCCCCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(CCCNCC(C)C)cc(-c3ccccc3)n2)CC1 +O=C(O)CNC(=O)c1c(O)c(-c2cccnc2)cc2nccnc12 +CN1CC2CCN(c3ccc(Oc4ccccc4)cc3)C2C1 +CCCCc1nc(Cl)c(C=O)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +NC1(C(=O)NCc2cccc(Cl)c2)CCN(c2ncnc3[nH]ccc23)CC1 +Cc1cnn(C)c1-c1cc2c(c3c1CCC3)NC(C)(C)C(=O)C2(C)C +CCN1CCN(Cc2cnc3c(C(=O)Nc4cccnc4)ccc(-c4c(Cl)c(OC)cc(OC)c4Cl)c3n2)CC1 +O=C(NC1CCCC(O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1CNC1CCC1 +CC(O)CNc1cc(Nc2cccc(Cl)c2)nc2c(C=C3NC(=O)NC3=O)cnn12 +O=C(O)c1ccc(C(=O)Nc2ccc3c(COc4cccc(Cl)c4)cccc3c2)cc1 +COC(Cc1ccc(OCCCOc2ccc(C(=O)c3ccccc3)cc2)cc1)C(=O)O +O=C1c2ccccc2C(=O)c2c1c(O)c1[nH]cc(CN3CC4CC3CN4)c1c2O +CCn1c(=O)c2c(nc(NC3CCCCC3)n2Cc2ccc(OC)c(Cl)c2)n(CC)c1=O +CCCn1c(=O)c2nc(-c3ccc(OCc4nc(-c5cccc(Cl)c5)no4)cc3)[nH]c2n(CCC)c1=O +CN(C(=O)NCc1ccccc1)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 +CC(C)(C)OC(=O)N1CCC(OC2CCC(Oc3cnc(C#N)cn3)CC2)CC1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)nc(NS(C)(=O)=O)n1 +CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4ccc(OC)cc4)c23)c1 +O=C1OC2(CCN(c3nc4cc(F)ccc4[nH]3)CC2)c2ccccc21 +COc1ccc(-c2ccc3onc(NC(=O)C4CCCCC4)c3c2)cc1OC +OC1(Cc2ccccc2)CCN(CCC#Cc2c[nH]cn2)CC1 +CN1CCC(NC(=O)Nc2cccnc2)CC1c1nc2ccccc2[nH]1 +N#CC1(CNCc2cccc(-n3cccn3)n2)CCN(C(=O)c2ccc(Cl)c(Cl)c2)CC1 +O=C(O)CC(O)CC(O)C=Cc1c2c(nn1-c1ccc(F)cc1)C(Cc1ccc(F)cc1)CCC2 +COc1ccccc1C(Br)=C(NC(=O)c1ccc([N+](=O)[O-])cc1)C(=O)N1CCCCC1 +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(NC2CCOC2)C1 +CS(=O)(=O)NC1CCC(CCN2CCN(c3cccc(C(F)(F)F)c3)CC2)CC1 +CN1C(=N)NC2(c3cc(-c4cccc(C#N)c4)cs3)CN(c3ncccc3C#N)CC2C1=O +CCc1ncnc(N2CCN(C3CC3)CC2)c1C#Cc1ccc(N)nc1 +CC(C)(C)OC(=O)N1CCC(N(C(=O)c2ccc(-c3ccsc3)cc2)C2CC2)CC1 +Cc1nc(C(C)(CS(C)(=O)=O)NC(=O)c2cc(OC(C)C(F)(F)F)c(C3(F)CCC3)cn2)no1 +NC(=O)c1ccc2c(c1)CCOC2CCN1CC=C(c2csc3cc(F)ccc23)CC1 +COC(=O)C1C(=O)c2c([nH]c(C(=O)OCCSC)c2C)CC1C +NC(=O)c1ccc2c(c1)C13CCCCC1C(C2)N(CC1CCC1)CC3 +CC(=O)NC(Cc1ccccc1)C(=O)NNC(=O)NC(C(=O)NCc1ccccc1)C(C)C +CC(C)(C)c1cc(N2CCC(=O)NC2=O)cc(C(=O)Nc2ccc(NS(=O)(=O)CCN3CCOCC3)cc2)c1O +Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)Nc5cccc(F)c5)c4)CC3)cccc2n1 +CC(Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC2CCCC2)cc1Cl +O=C(Cc1ccccc1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccn3)s2)s1 +COc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)cc2c1OCO2 +FC(F)(F)c1ccc(Nc2nc(Nc3ccccc3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CNC(=O)c1nc(-c2cccc(S(=O)(=O)Nc3cccc(F)c3F)c2)cnc1N +Clc1ccc2c(NCCNCCNc3ccnc4cc(Cl)ccc34)ccnc2c1 +COc1cccc(Cl)c1-c1nc(CN2CCC(C(=O)NCCCN3CC(C)CC(C)C3)CC2)c(C)o1 +CC(C)(C)OC(=O)NC(C)(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NCc1ccc(O)cc1 +COC1C=CC=C(C)C(=O)NC2=CC(=O)C(N)=C(CC(C)CC(OC)C(F)C(C)C=C(C)C1OC(N)=O)C2=O +Nc1ccc2[nH]cc(C3CCN(C(CO)C4CCN(C(=O)C=Cc5cc(F)c(F)c(F)c5)CC4)CC3)c2c1 +CN1CCN(c2cnc(-c3nc(C4(c5ccc(-c6cnc(N)nc6)nc5)CCC4)no3)cn2)CC1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1cc(-c2ccc(Cl)c(Cl)c2)no1 +O=C(Nc1ccccc1)N1CCC2(CC1)OCCN2S(=O)(=O)c1ccccc1 +Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CC2CN(Cc3ccccc3)CC2C1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CCCS(C)(=O)=O)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +COC1(C#CC(O)(Cc2ccccc2)Cc2ccccc2)CN2CCC1CC2 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccc(Cl)c(Cl)c4)oc3C)ccc21 +CN(C)CCOc1ccc2c(c1)COc1cc(Nc3ccc(F)cc3F)ccc1C2=O +Cn1cnc2c(C#N)nc(-c3ccc(OCCC4CCN(S(C)(=O)=O)CC4)c(C(F)(F)F)c3)cc21 +Cc1cc(CN2CCc3cc(S(=O)(=O)Nc4ccc(CCCC5CCCC5)cc4F)ccc3C2)c(C)n1-c1ccncc1 +O=C(Nc1cccc(-c2cnc3c(NC(=O)c4cc(Cl)cc(Cl)c4)nccn23)c1)Nc1ccc(F)cc1F +COCOc1ccc(CNC(=O)CCCCCN2CCN(c3ccccc3-c3ccc(OC)cc3)CC2)cc1 +N#Cc1ccc(OCC2CCN(Cc3ccccc3I)CC2)cc1 +O=C(O)c1cccc2[nH]c(-c3c(F)c(F)c(-c4cccnc4)c(F)c3F)nc12 +COc1cc(OC)c(C(=O)CCCCN2CCC3(CC2)NC(=O)NC3=O)cc1NS(=O)(=O)c1ccc(Cl)cc1 +NC1CCC(NC2CC2c2cnc(-c3cccc(O)c3)s2)CC1 +COC(=O)c1oc2cc(O)c(O)cc2c1-c1c(C(=O)OC)oc2cc(O)c(O)cc12 +O=S(=O)(Nc1cc(-c2ccc3nccc(-c4ccncc4)c3c2)cnc1Cl)c1ccc(F)cc1 +CCN(CC)CC1CC2c3ccccc3Cc3ccccc3N2O1 +COC1CCC(C(=O)N2CCC3(C)c4ccccc4CC2C3(C)C)CC1 +Cn1c(=O)ccc2c(NC(=O)NC3CCOc4ccc(F)cc43)cccc21 +COc1cc(SC)ccc1C1CC(c2c(O)cc(C)oc2=O)=NCCS1 +CN(Cc1ccccc1)C(=O)c1cc2c(C(=O)OC(C)(C)C)ncn2c2ccccc12 +Cc1cnc(CNC(=O)c2ccc(-c3cc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)s2)cn1 +COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O +CC(C)c1ccc(S(=O)(=O)N2CCCN(Cc3nc4cccc5c(=O)[nH]nc([nH]3)c45)CC2)cc1 +O=C(O)CCC(CP(=O)(O)C(O)c1cccc(F)c1)C(=O)O +C=CCC1(C)Oc2c(ccc(O)c2C)-c2c(C)cc(O)c(C)c21 +CCN(CC)C(=O)c1ccc(N(c2cccc(OC)c2)C2CCN(CCc3ccco3)CC2)cc1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCC(C)CC2)C1=O)c1ccccc1 +CC(CCCNC(=O)c1ccccc1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(C(=O)C(Cc2cc(OC)c(OC)c(OC)c2)=C(C(=O)O)c2ccc3c(c2)OCO3)cc1 +CCCn1c(-c2ccc(C(=N)N)cc2)nc2cc(C(=N)N)ccc21 +CN1CCC(c2c(O)cc(O)c3c(=O)cc(C=Cc4c(F)c(F)c(F)c(F)c4F)oc23)C(O)C1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)C1CCC(N)CC1 +CN1CCC(C2CNc3ccc(NC(=O)c4ccc(F)cc4)cc32)CC1 +CC1=C(C(=O)NCc2ccc(C(F)(F)F)cc2)OC2OC3(C)CCC4C(C)CCC1C24OO3 +N#CN=C(NCCOc1ccccc1)NCC1CCC(c2c[nH]cn2)C1 +CC1OC(=O)C1NC(=O)OCc1ccc(-c2ccccc2)cc1 +c1ccc2c(c1)Cc1c(Nc3ccc4c(c3)OCCO4)n[nH]c1-2 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(CC2CC2)C1 +COc1ccc2c(CC(=O)O)c(C(=O)c3cc(C)ccn3)[nH]c2c1 +CCCc1nn(-c2cccc(OC)c2)c2ncnc(NN=Cc3ccncc3)c12 +O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1 +O=C(CCc1ccccc1)Nc1ccc2cc(C(=O)NO)sc2c1 +CCCn1c(=O)[nH]c(=O)c2[nH]c(C3CCCCC3)nc21 +COc1ccc(C(CN2CCCC2)N(C)C(=O)Cc2ccc(Cl)c(Cl)c2)cc1OC +Cc1c(C(=O)N(C)C(=O)C2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +N#Cc1cccc(S(=O)(=O)NC2CCC(Nc3cc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)CC2)c1 +O=c1cc(Cc2c(F)cccc2F)nc(N2CCCCC2)[nH]1 +C=C(C)C1Cc2cc3c(cc2O1)CCNC3Cc1ccc(OC)c(OC)c1 +O=[N+]([O-])c1ccc(N2CCN(Cc3ccc([N+](=O)[O-])o3)CC2)cc1 +COc1cc(C(=O)NC2(c3ccccc3)CCC2)ccc1-c1cn[nH]c1 +CC(=O)N1CCC(c2nccnc2OC2CN(c3nc4ccccc4[nH]3)C2)CC1 +NC(=O)c1cnc(NCCc2ccc(O)c(Cl)c2)nc1NCc1ccccc1 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+O=S(=O)(c1ccccc1)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1CO +CC(C)N1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +c1coc(-c2nc(-c3ccco3)c(-c3ccco3)nc2-c2ccco2)c1 +CCN(CC)CCCCCOc1ccc2c(=O)cc(-c3ccccc3)oc2c1C +CC(C)n1nc(-c2ccc3[nH]ncc3c2)c2c(N)ncnc21 +CN1CCCN(CCOc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +Cc1c(N(CC2CCN(c3ccccc3)CC2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +COc1ccc(N2CCOc3cc(S(=O)(=O)Nc4nccs4)ccc32)c(OC)c1 +CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OC(CCc1ccccc1)c1cccc(C(=O)c2ccccc2)c1 +O=C1CC2(CCN(CCC(CN3C(=O)NC(Cc4ccccc4)C3=O)c3cccc(Cl)c3)CC2)c2ccccc21 +Cc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cccnc4)c3)ccnc21 +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)N(C)C3CCCC3)c12 +O=C(O)c1ccc2c(c1)C13CCCCC1C(C2=O)N(CC1CCC1)CC3 +CC(=NNC(=O)c1nnn(-c2nonc2N)c1-c1ccccc1)c1ccccc1O +CNc1cccc(-c2c(-c3ccc4nn(C)cc4c3)nsc2NC(=O)C2CC2C)n1 +Cc1ccc(CNc2ccnc(Nc3ccc(C#N)cc3)n2)cc1C +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C1CCC1)CC2 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+C=CCNCC(O)COc1cccc2c(=O)c3ccccc3oc12 +C#CC(C)(C)Nc1c(C#N)cnc2cnc(NCc3cccnc3)cc12 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1nccc2ccccc12)C(C)C +CCN1CCCC1CNc1[nH]cnc2c3cc(Cl)ccc3nc1-2 +COc1ccnc2[nH]cc(C(=O)c3c(F)ccc(NS(=O)(=O)c4cc(F)ccc4F)c3F)c12 +O=C1CC(c2c(Cl)ccc(NC3CCOCC3)c2Cl)CC(O)=C1Sc1ccccc1Cl +O=C(CN(CCC1CCCC1)C(=O)N1CCCC1C(=O)Nc1ccc2c(c1)OCO2)NO +COCCCN1CCC(O)(CNC(=O)c2nc(C(C)C)n3ccccc23)CC1 +CCCc1ncc(Cc2cnc3ccccc3c2)c2cc(OC)c(OC)cc12 +CC(C)(C)c1nc2cc(S(=O)(=O)CC3CC3)ccc2n1CC1CCN(C=O)CC1 +O=C1OC(c2ccccc2Cl)CN1c1ccc2c(c1)CNCC2 +CN(C)c1ccc(-c2oc3c(ccc4ccccc43)c(=O)c2O)cc1 +N#Cc1cnn(CC(O)COc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)c1N +CC1CCCCN1c1nn(CC(C)(C)O)cc1NC(=O)c1cnn2cccnc12 +CC1c2c([nH]c3ccccc23)C2Oc3c(O)ccc4c3C23CCN(CC2CC2)C(C4)C13 +CCCC(Oc1cnn(-c2ccc(C)cc2)c1)c1ccc(C(=O)NCCC(=O)O)cc1 +Sc1nc(-c2ccc(Cl)cc2Cl)nn1Cc1cccc(Oc2ccccc2)c1 +Cc1oc(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)Nc2ccccn2)nc1C(=O)O +CCc1ccnc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 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+NC(=O)c1cccc2c(NC(CN3CCCC3)c3ccccc3)ncnc12 +O=C(c1c(F)ccc(NS(=O)(=O)c2cccnc2)c1F)c1c[nH]c2nccc(Cl)c12 +CC(C)Nc1cc(-n2ccc3cc(CNC(=O)CC(C)(C)C)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +Cc1cc(=O)oc2cc(O)c(-c3ccc(C#N)n3C)cc12 +CN(c1ccnc(NC(=O)C2CC2)c1)c1c(Cl)cnc2c1OCO2 +CCOc1ccc2ccccc2c1C(=O)N1CC2CN(c3nc(C)cc(C)n3)CC2C1 +COc1ccc(CNC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)c(F)c1F +O=C1N=C(N2CCOCC2)SC1=Cc1cccc2ccccc12 +[H]C(c1nc[nH]c1C(C)(C)C)=c1[nH]c(=O)c(=Cc2ccccc2)[nH]c1=O +O=c1[nH]cnc2c(CNCCCCP(=O)(O)O)c[nH]c12 +CN(C(=O)COC(=O)C=Cc1cccc([N+](=O)[O-])c1)C1CCS(=O)(=O)C1 +CS(=O)(=O)c1ccccc1-c1cccc(OCC(O)CN2CCc3ccccc3C2)c1 +Nc1ccn(C2CSC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)n1 +Cc1cnn(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +Cn1cc(-c2nnc(Nc3ccc(Cl)cc3)s2)c2ccccc21 +CC(C)(C)c1ccc2c(c1)CCC2NC(=O)Nc1cccc2cnccc12 +Cc1cc(-c2nnc(NCC3OCCO3)o2)nc2c(C(F)(F)F)cc(OCC(F)(F)F)cc12 +NC(=O)c1cccc(NCC2=CCC(c3cc(F)c(F)c(F)c3)C(N)C2)c1 +NC(=O)c1nc(NCCO)nc(-c2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)n1 +CN(C)c1ccc(-c2nc3cc(NC(=O)c4ccc(I)cc4)ccc3o2)cc1 +CNC(Cc1nc(-c2ccc(O)cc2)no1)C(=O)Nc1ccccc1C(=O)O +Cc1c(F)cncc1-n1c(C(Nc2nc(N)nc(N)c2C#N)C2CC2)nc2c(F)ccc(Cl)c2c1=O +CC(c1ccc2ncccc2c1)c1nnc2ccc(-c3ccc(F)c(F)c3)nn12 +O=C(CC1CCCCN1c1ccnc(-n2ccnc2)n1)NCc1ccc(C(F)(F)F)cc1 +Cc1cc(-c2cccnc2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc12 +Cc1ccc(-c2c(CN)c(CC(C)C)nc(C)c2C(=O)OCc2ccccc2C(=O)O)cc1 +CCCCC(=O)N(Cc1ccc2c(c1)OCCO2)c1cc(F)cc(-c2nnn[nH]2)c1 +N=C(N)c1ccc(Oc2ccc(-c3cc4ccc(C(N)=NCCCNc5ccnc6cc(Cl)ccc56)cc4[nH]3)cc2)cc1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CC(NC(N)=O)c2ccccc2)CC1 +CCCCCNC(=O)NCCCCC=CCCCCCCCc1nnn[nH]1 +O=C(Nc1nc(-c2ccccc2)nc2cn(Cc3ccccc3)nc12)c1ccccc1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2cccc3nsnc23)c2cc[nH]c2c1=O +O=C(O)c1cc(-c2ccc(O)cc2)n(-c2ccc(Cl)c(Cl)c2)n1 +CN(C)CC1CCN(c2c(C(=O)C3CC3)cnc3ccc(-c4ccc5[nH]ccc5c4)cc23)CC1 +COc1cc2c(cc1OCc1ccccc1)N(C(=O)OCc1ccc([N+](=O)[O-])cc1)C(O)C1CCCN1C2=O +CCC(C)Oc1cccc(N(Cc2cccnc2)S(=O)(=O)CC(F)(F)F)c1 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+O=C(NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCN2CCCCC2)N1)c1ccc(Cl)cc1 +COc1cc(C(=O)c2cccc(-c3ccccc3)n2)cc(OC)c1OC +C(C#Cc1ncnc2c1ncn2Cc1ccccc1)#Cc1ncnc2c1ncn2Cc1ccccc1 +Cc1c(Cc2nn(Cc3ccccc3)c(=O)c3ccccc23)c2cc(Cl)ccc2n1CC(=O)O +O=C(NCC1CCCC1)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +Clc1ccc(-c2cc(C3CCN(CCCc4ccccc4)CC3)[nH]n2)cc1 +CN(C)CCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 +CC(C)OC(=O)N1c2ccccc2CC1C(=O)NC(C(=O)c1nnc(C(C)(C)C)o1)C(C)C +Cc1ccc(CCN2CCC=C(CCC(=O)NO)C2=O)cc1 +COc1ccccc1-c1cn2c(-c3ccc(Cl)c(F)c3)c(CN)c(C)nc2n1 +COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)ccc2OC)C3=O)c(OC)n1 +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1C(CC#N)COc1ccccc1 +CCOC(=O)c1ccc(-c2nn(-c3ccco3)c3ccccc23)cc1 +Cc1cc(-c2cc(C3CCN(C)CC3)[nH]c2-c2ccc(F)cc2)ccn1 +CC(C)(C)NC(=O)c1c[nH]c2ncc(Nc3cncc(S(C)(=O)=O)c3)nc12 +COc1ccc(NC(=O)c2cccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4OC)cc3)c2)cn1 +NC1CCCC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C1 +Cc1nc(C(=O)N2CCC2)c(C(=O)NCCc2nc(-c3ccccc3)cn2C)n1C 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+COc1ccc(NC(=O)N2CCC(Nc3ncc(C(=O)c4ccccc4OC)c(N)n3)CC2)cc1 +COc1cc([N+](=O)[O-])c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1 +CN(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C(=O)C1CCN(c2ccncc2)CC1 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1(S(=O)(=O)Cc2ccccc2)CCCC1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(C)(=O)=O)cc2)n(-c2cccc(C(=N)N)c2)n1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)NC(CCCNC(=N)N)C(N)=O)cc1 +CCn1ncc2c(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)Nc4cccnc4)cc3)nc21 +Cc1ccc(C2OC(CO)C(O)C(O)C2O)cc1Cc1ncc(-c2ccco2)s1 +[C-]#[N+]c1scc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CO2)c1C +CC(C)C(O)C(C)(OCc1ccc(-c2ccccc2)cc1)C(=O)NO +CCc1c(Sc2ccccc2)n(CC2CC=CC2)c(=O)[nH]c1=O +CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1CC2OCC(O)C2C1)S(=O)(=O)c1ccc(N)cc1 +NN(NC(=S)Nc1ccc(S(N)(=O)=O)cc1)c1c(F)c(F)c(F)c(F)c1F +COc1ccc2c(c1)C(=O)N(c1nc(C(=O)Nc3cnccc3N3CCNCC3)cs1)C2 +CC(COc1ccc(-c2ccc(=O)n(C)n2)cc1)CN1CCCC1C +CCn1ncc(-c2ccc3c(c2)c(C2CCN(CCN4CCNC4=O)CC2)cn3-c2ccc(F)cc2)n1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(OCCC2CCCCC2)cc1F +CC1CCC(n2c3cnccc3c3cnc(Nc4ccc5c(n4)CCN(CCCO)C5)nc32)CC1 +CC(C)CC(CC(=O)NO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCc1ccc(CN(C)C)cc1 +CCC1CN2CCc3c([nH]c4ccccc34)C2CC1C(=COC)C(=O)OC +NC1(C(=O)NC(CCS(N)(=O)=O)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 +O=C(Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1)OCC(F)(F)F +CNS(=O)(=O)N1CC(OC)C(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +CCCCc1nc2ccn(Cc3cccs3)c(=O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(O)CC(NC(=O)CCC(=O)Nc1ccc2c(c1)CNCC2)c1ccccc1 +COC(=O)N1C2CCC1CC(O)(C#Cc1cccc(C)c1)C2 +Cc1cc(-c2nc3ccc(C(C)C)cc3n2C(C)c2ccccn2)cn(C)c1=O +CNC(=O)c1cccc(Oc2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2C(F)(F)F)c1 +OC(COCc1ccco1)CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +COC(=O)N1CCC(c2ccccc2)(c2nccn2Cc2ccccc2)CC1 +O=C(NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1)NC(CN1CCOCC1)c1ccccc1 +Cc1cc2c(NC(=O)NC3CC(C)(C)Oc4c(F)cc(F)cc43)cccc2cn1 +CS(=O)(=O)C1CCN(Cc2cc3c(N4CCOCC4)nc(-c4cnc(N)nc4)nc3s2)CC1 +CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)ccc(F)c1F +Cn1c(=O)c(Oc2ccc(F)cc2F)cc2cnnc(-c3ccc(F)cc3F)c21 +CCCN(CCC)C(=O)CC1=C(c2ccc(Cl)cc2)NC2C=CC(Cl)=CN12 +COC(=O)C1C(c2ccc(I)cc2)CC2CCC1N2Cc1ccccc1 +O=C(COc1ccccc1)N1CCCCC1c1noc(-c2cccc3[nH][nH]c(=O)c23)n1 +CCc1cccc(NC(=O)c2cc(Oc3cncc(F)c3)cc(C)n2)n1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c4c(ccc3nc2-1)OCN(c1ccccc1C)C4 +COc1cc(O)cc(N(CCNC(C)C)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1 +Cc1c(COC(=O)NC(C)C)c(COC(=O)NC(C)C)c2n1Cc1ccccc1C2 +C=C(C)CCCC1(C)C2=C(CCC1C)C1(C)CCC2C(O)(C2=CC(=O)OC2O)C1 +CC(Nc1nccc(Nc2cc(C3CC(F)(F)C3)[nH]n2)n1)c1ccc2[nH]ccc2n1 +NC(=O)C1CCCN1C(=O)C(Cc1nc(Br)[nH]c1Br)NC(=O)c1cnccn1 +N#Cc1ccc(-c2ccc(CC(C#N)NC(=O)C3CNCCCO3)cc2)cc1 +CNC(Cc1cn(C)c2ccccc12)C(=O)NC(C(=O)N(C)C(C=C(C)C(=O)O)C(C)C)C(C)(C)C +Cc1cc(C(=O)O)c2nc(-c3c(F)c(F)c(-c4ccc(F)c(F)c4)c(F)c3F)[nH]c2c1 +O=C(NC1CCCC(Nc2nc(-c3c[nH]c4ncccc34)ncc2F)C1)N1CCOCC1 +O=C(O)C(Cc1ccc(O)cc1)NC(=O)C(Cc1ccccc1)C(S)CCc1ccccc1 +CC(NC(=O)Cc1cccnc1)C(=O)NC1C(=O)N(C)N=Cc2ccccc21 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)CC3CCOCC3)c12 +CC(C)c1cc(-c2ccccc2)cc(C(C)C)[n+]1CCc1ccc(S(N)(=O)=O)cc1 +COCCCOc1cc(C(=O)N(CC2CNCC2NCc2ccccc2)C(C)C)ccc1OC +COc1ccccc1C=Cc1nc(S(=O)(=O)c2ccccc2)c(N(C)C)o1 +CCOc1cc(NS(C)(=O)=O)c(OCC)cc1CNC(=O)Nc1ccc(C)cc1 +CC(C)Oc1ccc(N=c2[nH]c(=O)n(CCC(=O)NCC#N)c(=O)n2Cc2ccc(Cl)cc2)cc1F +CCCc1c(OCCCCCc2cccc(O)c2O)ccc(C(=O)O)c1O +O=C1OCCCN1C(CCc1ccncc1)COc1ccc(-c2cccc([N+](=O)[O-])c2)cc1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C(C)N +O=C(O)CC(CCCCCCc1ccc2c(n1)NCCC2)c1cccc(F)c1 +Cc1cc(C(=O)Nc2cc(C(C)(C)C)nn2C)cc(Nc2ncnc3cnc(N4CCN(C)CC4)nc23)c1C +NC1CC(N2Cc3nn4cccnc4c3C2)COC1c1cc(F)ccc1F +Cc1cc(-c2n[nH]c3ccc(C(=O)NC(C)c4c(Cl)cnc(Cl)c4Cl)cc23)ccn1 +c1ccc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)cc1 +O=C(COP(=O)(O)O)N(O)CCCCOP(=O)(O)O +O=C(NN=Cc1c(-c2ccc(O)cc2)[nH]c2ccccc12)c1ccc(Cl)cc1 +O=C(NC(c1ccc(Cl)c(Cl)c1)C1CCNCC1)c1ccc2[nH]ncc2c1 +C=CC(=O)N1CCC(Oc2ccc3ncnc(Nc4ccc(F)c(Cl)c4F)c3c2)C1 +COc1ccc(-c2n[nH]c(NCc3c(F)cccc3Cl)n2)cc1OC +O=C1CN(C(=O)Nc2cnc3ccc(N4CCCC4c4cc(F)ccc4F)nn23)CCN1 +CCCc1c(OCc2ccc(C=C3SC(=S)NC3=O)cc2)ccc(C(=O)c2ccccc2)c1O +CN1CCN(c2nc3cc(OCc4ccccc4)ccc3n3cccc23)CC1 +CCN(Cc1c(C)nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n12)CC1CC1 +COc1cccc(CN2CCN(c3cc(N4CCCC4)nc(N4CCCC4)n3)CC2)c1 +CCN(CC)CCCOc1ccc(C=Cc2nc3ccccc3o2)cc1 +Clc1ccc2nc(CCNCc3ccc(-c4nnc5n4-c4cccnc4Nc4ccccc4-5)cc3)[nH]c2c1 +O=C(O)C=Cc1ccc(Cn2ccnc2)cc1OCCc1cc2ccccc2o1 +CCOc1ccc(S(=O)(=O)Nc2cc(OC)ccc2OC)cc1 +COCCNC(=O)c1cccc(-c2cccc3cc(Cc4cccc(C(F)(F)F)c4)sc23)c1 +Cc1ccc2c(c1)C(=NNc1ccc(S(N)(=O)=O)cc1)C(=O)N2 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1ccccc1F +COc1ccccc1COc1ccc(Br)cc1Cn1nc(C(=O)O)cc1C +COc1ccc(CCO)c(Nc2nc3ccccc3nc2NS(C)(=O)=O)c1 +NC1(c2ccc(-c3nc4c(F)cc(F)cn4c3-c3ccccc3)cc2)CCC1 +CC(C)CC(NC(=O)C(NC(=O)c1cncc(-c2ccccc2)n1)C(C)O)B(O)O +Cc1nc(C)n(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C(F)(F)F)n2)n1 +COc1ccc(S(=O)(=O)N(Cc2ccccc2)c2c(C(=O)NO)csc2Br)cc1 +CCCC12CCC(=O)C=C1c1ccc(OCC(=O)O)cc1C2 +CCCNC(=O)c1c(N)n(-c2ccc(S(N)(=O)=O)cc2)c2nc3ccccc3nc12 +COc1ccc2c(c1)CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)S2(=O)=O +CS(=O)(=O)c1cc(-c2ccc(CC(C#N)NC(=O)C34CCC(CC3)CN4)c(F)c2)ccc1C#N +CC(C)(C)c1ccc(OCCC(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +Clc1ccc(-c2cn(Cc3cccc(Cl)c3)c3c2CNCC3)cc1 +COc1ccc2c(c1)CCC1CN(CCC3CCC(NC(=O)c4cnc5ccccc5n4)CC3)CCN21 +Cc1cc(NCCN2CCCCC2)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +O=C(O)c1cccc(C=Cc2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C3CCCC3)cc2Cl)c1 +COc1cccc(CC2C(O)C(O)C(Cc3cccc(OC)c3)N(Cc3ccccc3)C(=O)N2Cc2ccccc2)c1 +C#CCOc1cnc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)OCC3(F)F)c2)cn1 +CCN(CC)Cc1cc(NCCN2CCCCC2)cc(Nc2ccnc3cc(Cl)ccc23)c1 +COc1ccccc1C(=O)Nc1cc2c(cc1N1CCNCC1C)n(C)c(=O)n2C +CC=CC=CC(=O)NC(CC(=O)NC(C(=O)C1C(=O)N(NC)C(=O)C1C)C(C)C)c1ccccc1 +CNC(=O)NCc1ccccc1C1(O)CCN(C(c2ccccc2Cl)c2ccccc2Cl)CC1 +Cc1ccc(C(=O)Nc2ccc(N(C)CCN(C)C)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCCCC3)nc12 +CC(C)=CCOC(=O)c1sccc1S(=O)(=O)N1c2cc(Cl)ccc2NC(=O)C1C +COc1cccc(-c2cc(NC3CCCc4ccccc43)nc(C)n2)c1Cl +CC(C)(C)NC(=O)C1CCN(Cc2cc(NC(=O)Cc3ccccc3Cl)cs2)CC1 +O=C1CN(C(=O)c2cc(NC(=O)c3cc(-c4ncccc4F)c(F)cc3Cl)n(-c3ccccc3)n2)CCN1 +O=C(O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc2ccccc2c1 +Cc1cc2c(-c3nc4c(c(C5(S(C)(=O)=O)CCC5)n3)OCC3COCCN43)cccc2[nH]1 +CCN(C(=O)COc1ccc2ccccc2c1)c1ccc(OC)nc1 +Cn1c2nc3ccccc3c-2c(NCCCN2C(=O)CCSC2c2ccc(F)cc2)c2ccccc21 +O=C1Cn2c(Cl)cnc(c2=O)NC(Cc2ccccc2)CNCCCCNCc2ccccc2CN1 +COc1cc2c(cc1OC)CN(CCCCn1cc(-c3ccoc3)c3ccccc31)CC2 +O=C(O)CCC(NC(=O)c1cccc(-c2ccccc2)n1)C(=O)N1CCN(C(=O)OCC(F)(F)F)CC1 +Nc1ncnc2c1c(-c1cc3c(Cl)cccc3[nH]1)nn2CC1CCNCC1 +CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C=O)cc2C)c1C +C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCNC(C)=O +Cn1cc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cccc(Cl)c2)C(N2CCC2)CC3)cn1 +COc1ccc2c(c1)NC(=O)Cc1cnc(Nc3ccc(O)c(Cl)c3)nc1-2 +COc1cc(-c2cc(-c3cc(C)cc(Cl)c3O)nc3ncnc(N)c23)ccc1O +COc1ccc2c(c1)N(CC1CC1)C(C#CC1CC1)(C(F)(F)F)C(=O)N2 +CNC(=O)c1cc(S(=O)(=O)N2CCN(c3ccccn3)CC2)cs1 +Cc1cnc(NC(=O)c2cc(Oc3cnc(C(=O)N4CCCCC4)cn3)c3cc(C)oc3c2)cn1 +CCN(Cc1ccc2ncnc(S)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +CCOc1ccc(F)c(-c2nc(C)c3nnc4ccc(OC)nc4n23)c1 +CC1(C)CCCN(Cc2ccc(-c3cnc4[nH]c5cnc(C#N)cc5c4c3)cc2)C1 +CCCC1Cc2cc3c(C(F)(F)F)cc(O)nc3cc2NC1CC +CC(C)CC(C(=O)O)c1cc(Cc2cc(F)cc(F)c2)cc(-c2ccc(C(F)(F)F)cc2)c1 +CCc1c(CC)c(OC)c2c(C)cccc2c1OC(C)=O +NS(=O)(=O)Oc1ccc2sc(-c3ccccc3)cc(=O)c2c1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1C(=O)N1CCOCC1 +Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)OCc4ccccc4)c3Cl)cccc2s1 +COC1COCCC1NC1CCC(C(=O)N2CC3CC2CN3C(=O)CC(C)(C)C)(C(C)C)C1 +O=C(c1ccc(F)cc1)c1cc(F)ccc1C=COCCN1CCCC(C(=O)O)C1 +COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OC1COC2C(O)COC12 +O=c1cc(N2CCOCC2)oc2c(-c3ccc(Cl)cc3)csc12 +CC(O)(CSc1ccccc1Cl)c1cc2cc(Cl)c(C(F)(F)F)cc2[nH]1 +CCCCc1cc(=O)n2nc(-c3ccccc3)nc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(Nc1ccc[n+]([O-])c1)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +COc1cc(O)c(Cc2ccc(O)cc2)c2ccc3cc(O)ccc3c12 +COc1cc2c(Nc3ccc(Cl)cc3Cl)c(C#N)cnc2cc1OCCCN1CCOCC1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(N(C)CC)n3)C2)cc1 +NS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2ccccc2)cc1 +CC(C)(O)c1cn(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)c(C(C)(C)c2ccccc2Cl)n1 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+Cc1cc(C)c(C)c(Cn2ccc3c(C=NNC(=O)c4ccc(O)c(Cl)c4)cccc32)c1C +COc1ccc(C(=O)N2CCC(N3CC(CC#N)(n4cc(-c5ncnc6[nH]ccc56)cn4)C3)CC2)cc1F +CC1(c2cc(Nc3nc(N4CC(O)CC4C(=O)Nc4ncns4)nn4cccc34)[nH]n2)CC1 +Cc1ccc(OCC(C)(C)O)cc1-c1nnc2c(C)nc3ccc(C4CC4)nc3n12 +O=c1ccc2ncc(F)c3c2n1CC3(O)CC12CCC(NCC(F)=Cc3cc(F)ccc3F)(CC1)CO2 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)c3cccc(Br)c3)CC2)C1 +CC(NC1CCN(c2ccc(C(=O)N(C)C(O)C(O)C(O)C(O)CO)cc2)C1)c1cccc2ccccc12 +Cc1n[nH]c2nccc(-c3ccc(NC(=O)NCc4ccccn4)cc3)c12 +O=c1[nH]c2ccc(CN3CCCCC3)cc2n2cccc12 +COc1ccc(Cl)cc1Nc1cc(C(F)(F)F)nc(-c2cccnc2)n1 +CCNC(=O)c1ccc2cc(CCc3c(C(=O)O)[nH]c(=O)[nH]c3=O)ccc2c1 +O=C(O)c1cn(CCCO)c2ccc(Cc3ccc(Cl)cc3Cl)cc2c1=O +O=S(=O)(c1ccc(C(F)(F)F)nc1)N1C(C2CC2)c2cn[nH]c2C(F)(F)C1C1CC1 +COc1ccc(Cl)cc1C(=O)NNC(=S)NC(=O)c1cc(-c2ccccc2)nc2ccccc12 +O=C(NC1CCCN(CCO)CC1)N1CCC2C1C(=O)N2S(=O)(=O)O +CNC(C)C(=O)NC(C(=O)N1CCc2ccccc2C1C(=O)Nc1c(F)cccc1F)C1CCCCC1 +O=C1C(=O)N(CCCCn2cc(COc3ccc(C=NNc4ccnc5cc(Cl)ccc45)cc3)nn2)c2ccc(Cl)cc21 +Cc1noc(=O)c2ccc(NC(=O)C(O)(CC3CCCc4c(C#N)cccc43)C(F)(F)F)cc12 +CCCNC(=O)c1ccc(CN(C2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCC(=O)N(C)C)c12 +C=CCSc1nnc2c(n1)OC(c1cccs1)N(C(=O)CC)c1ccccc1-2 +Fc1ccc(-c2cc(NC3CCC(NCC4CCO4)CC3)ncc2Cl)nc1NCC1CCOCC1 +C=CC(=O)C(CCN(C)C)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +O=C(C=Cc1cccc(OCC(Cc2c[nH]c3ccccc23)NC(=O)c2ccc(Cl)cc2Cl)c1)NO +NC(=O)Cn1cc(-c2cc(Cl)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +Nc1ccc(S(=O)(=O)n2cc(C3=CCNCC3)c3cc(F)ccc32)cc1 +O=c1[nH]c2c([nH]c3ccccc32)c(=O)n1CCN1CCN(c2ccccc2Cl)CC1 +CCCCC(C=NNC(=O)N1CCOCC1)NC(=O)OC(Cc1ccccc1)C(C)C +CC1CC[n+]2ccn(CC3CC(c4ccccc4)(c4ccccc4)C(=O)O3)c2C1 +CCN1C2=C(C(=O)Nc3ccncc3)C(=O)CCN2c2ccccc21 +CNCc1cc(C(=O)N2CCN(C(C)C)CC2)ccc1Oc1ccc(Cl)cc1 +COc1ccc(C2=[N+]([O-])c3cc(OC)ccc3C2=O)cc1 +CC1CN(c2nc(N3CCOCC3C)c3ccc(-c4ccsc4)nc3n2)CC(C)O1 +CCCCc1ncc(C=C(Cc2ccsc2)C(=O)O)n1Cc1ccccc1Cl +[C-]#[N+]C1CC(C(=O)N2CC(C)(C)C2)CCC1n1cc(C(N)=O)c(Nc2ccc(Cl)cc2)n1 +COc1cc2nc(NC(=O)CN3CCN(Cc4ccc(C(F)(F)F)cc4)CC3)sc2cc1OC +Nc1ncnc2c1c(-c1ccc3ccccc3c1)cn2C1OC(CO)C(O)C1O +Cc1nc(-c2ncn3c2CN(C)C(=O)c2ccccc2-3)no1 +Cc1ccc2oc(=O)c(-c3cccc(OCCCN(C)C)c3)cc2c1 +COc1ccc(-c2cnnn2Cc2cc(OC)c(OC)c(OC)c2)cc1O +CNc1ccccc1C(=N)CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +COc1ccc2c(c1)c(CC(=O)Nc1cccc(SC)c1)c(C)n2C(=O)c1ccc(Cl)cc1 +CC1CN=C(c2ccc(NC(=O)c3ccc(C(=O)Nc4ccc(C5=NCC(C)N5)cc4)c(N)c3)cc2)N1 +O=C(O)C1=C(C(=O)Nc2ccc(OCc3c(F)cccc3Cl)c(Cl)c2)CCC1 +COc1cccc2c1OC1CCCC3CN(CCc4ccccc4)CCC231 +Cc1c(NC(CC(C)C)c2ccc(C(=O)NCCC(=O)O)cc2)cnc2ccccc12 +O=C(O)c1ccc(CCCN2C(=O)CCC2CCC(O)Cc2cccc(Cl)c2)cc1 +CCc1cccc(CC)c1-c1cc(SC)c2c(n1)CCCC2N(CC)c1cccc2ccccc12 +O=C(CCCO[N+](=O)[O-])Oc1cccc(C(=O)Oc2ccc(-c3cc(=S)ss3)cc2)c1Cl +O=C(O)CCc1ccc(OCc2ccccc2-c2ccc(F)cc2)cc1 +Cc1ccc2c(OCCN3CCN(Cc4cccc5cccnc45)CC3)cccc2n1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cccc(C(C)(C)C)c3)ccc2[nH]1 +OCC1OC(n2cnc3c(NN4CCCC(Sc5ccccc5)C4)nc(Cl)nc32)C(O)C1O +O=C(Nc1ccccc1)c1c(NO)cc(-c2ccc(Cl)cc2)oc1=O +CCCCCCCC(=O)N1CCN(C(C#N)c2cccnc2)CC1 +O=C1c2ccccc2CCCN1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1 +CCc1c(C(C)c2c(F)cccc2F)nc(SC2CCCC2)[nH]c1=O +Nc1ncc(-c2ccc(-c3cccnc3S(=O)(=O)C3CCS(=O)(=O)CC3)cc2F)cn1 +Cc1c(CCN2CCc3c(cnn3-c3ccc4c(c3)COC4=O)C2)ccc2c1COC2=O +OC(CNc1cccc2ccccc12)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21 +C=CC(=O)Nc1cc(Br)cc(-n2c(=O)cc(C)c3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +COC1COCCC1NC1CCC(C(C)C)(N2CCN(C(=O)OC(C)(C)C)CC2)C1 +COc1cc(N2CCCCC2)ccc1Nc1ncc2ccnc(NCC(C)(C)C)c2n1 +Cc1nc(C(=O)COc2ccc(OCCCCCc3ccccc3)cc2)sc1CCCC(=O)O +CCC(CO)Nc1cc(-n2ncc3cc(Cl)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +O=C(c1ccc(-n2cccc2)cc1Cl)N1CCCCc2ccccc21 +CC(=O)Nc1ccccc1COc1ccc(-c2ccc(-c3nc4c(C(=O)O)cc(C)cc4[nH]3)cc2)cc1 +COc1ccc(CCCc2nc(N)c3nn(-c4ccccc4)cc3n2)cc1 +CS(=O)(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1C#N +CNC(=O)c1cccc(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1C +CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 +Brc1ccc(-n2c(-c3c(-c4ccccc4)[nH]c4ccc(Br)cc34)nc(-c3ccccc3)c2-c2ccccc2)cc1 +CCC1(CC)OC(S)=Nc2ccc(-c3ccc(C#N)n3C)cc21 +COc1ccc(Cn2ncc3[nH]c(-c4cc(NC(=O)Nc5ccc(Cl)c(Cl)c5)ccc4C)nc32)cc1 +O=C(Nc1ccc(C(=O)N2CC3COCCN3Cc3ccccc32)cc1)c1ccccc1-c1ccccc1 +O=S(=O)(NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1)c1ccccc1 +COc1cc(C(=O)c2c[nH]c(-c3ccc(N(C)C)cc3)n2)cc(OC)c1OC +CC1CCCN(S(=O)(=O)c2ccc(NC(=O)NCc3cccnc3)cc2)C1 +COc1ccc(Oc2ccc(NC(=Nc3ccccc3)NCCNc3ccnc4cc(Cl)ccc34)cc2)cc1 +CC(=O)OCC(COC(C)=O)c1ccc(NC(=O)c2ncc(C#N)[nH]2)c(C2=CCCCC2)c1 +CC(O)C(c1ccccc1)N1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +COCCCS(=O)(=O)c1cccc(Oc2cccc(-c3c(C)cnc4c(C(F)(F)F)cccc34)c2)c1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCNCC2)cc1 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1c(C)cccc1F)C(C)C +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2CF)o1 +COc1ccc(CC(C(=O)c2ccc(OC)cc2)=C(C(=O)O)c2ccc3nsnc3c2)cc1 +COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc(-c4cccc(Cl)c4)[nH]c3c2=O)CC1 +Cc1ccc(NC(=O)Nc2ccc(C=CC(=O)c3ccc(Cl)cc3)cc2)cc1 +COCc1nc2c(C(=O)Nc3nc4ccc(Cl)cc4o3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CC1c2ncn(-c3ccc(F)cn3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl +CCCCN(CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(c2ccccc2)CC1)C(C)=O +NC1=NC2(CCSCC2)N(OCCCOc2cccc(Cl)c2)C(N)=N1 +COc1ccc(CC(NC(=O)C(CC(=O)O)NC(=O)CCCOc2ccc(C(=N)N)cc2)C(=O)O)cc1 +Cc1cccc2c1[nH]c(=O)n2CC(=O)Nc1ccc2c(c1)CC1(C2)C(=O)NC(=O)N1C +CN1CCN(Cc2ccc3n2Cc2ccccc2N(C(=O)c2ccc(NC(=O)c4ccccc4-c4ccccc4)cc2Cl)C3)CC1 +COc1ccc2c(c1)-c1ccc3c(c1CO2)C(C)=CC(C)(C)N3 +CN(C)CCCOc1ccc(NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)cc1 +NC(CNc1cc(-c2ccncc2)c(-c2cccc3ccccc23)nn1)Cc1ccccc1 +CCCn1c(=O)c2nc(C3CCC(OC(=O)c4cccc(S(=O)(=O)F)c4)C3)[nH]c2n(CCC)c1=O +CCCCCCCCC(C)(C)c1ccc(C2CC(O)CCC2CCCO)cc1 +CS(=O)(=O)c1ccc2c(c1)N(CCCN1CCC(C(=O)O)CC1)c1ccccc1S2 +OCC1OC(n2cnc3c(NC4CC4)ccnc32)C(O)C1O +COC(=O)c1ccc(CS(=O)(=O)NCB(O)O)cc1 +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccc(NC(=O)Nc3ccccc3)cc2o1 +COc1ccc(-c2ccc3ncc4c(c3n2)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C4)cn1 +CN1CCC(c2cc3c(-c4cncc(NCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +O=C(NCc1ccccc1)Nc1cccc(CCNCC(O)c2ccc(O)c3[nH]c(=O)ccc23)c1 +COc1ccccc1C(=O)C=Cc1ccccc1[N+](=O)[O-] +CC(C)c1cc(C(=O)N2Cc3ccc(Cl)cc3C2)c(O)cc1O +Fc1ccc(-c2ccc(OCC3CCN(CC4CC4)CC3)cc2)cc1 +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)N(CC)CC)c3ccc(F)cc3F)CC2)c(F)c1 +CCOCCn1nc(C)c2nc(NC3CCNCC3)nc(Nc3cc(C)ccn3)c21 +CC(C)CC(C(=O)O)c1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccc(C(F)(F)F)cc2)c1 +O=C(Nc1ccc(-c2cccnc2)cc1)Nc1ccc(OC(F)(F)F)cc1Br +NC(=O)N1CCCc2cc(-c3cncc(C4CCC(=O)N4)c3)cnc21 +CCOCc1ccc2c(c1)nc(NC(=O)c1cccc(C(F)(F)F)c1)n2C1CCC(O)CC1 +CCCN(CCCNc1ccnc2cc(Cl)ccc12)Cc1ccsc1 +CCC(C1CC1)n1cc(C#N)nc(Nc2cc(C)c(OC)nc2C)c1=O +CC(C(=O)NO)N1CCC(C)(c2ccc(-c3ccccc3)cc2)C1=O +COc1cccc(-n2c(=O)n(CCC(N)c3ccccc3C)c(=O)n(Cc3c(F)cccc3F)c2=O)c1 +O=C1CC(NC(=O)C2COCC3CC=CCC(NC(=O)c4ccc(Cl)cc4)C(=O)N32)C(O)O1 +CCOC(=O)N1CC2CCC(C1)C2NCCNC(=O)c1ccccc1 +Oc1ccc2c3c1OC1C(OCc4ccccc4N=C=S)CCC4(O)C(C2)N(CC2CC2)CCC314 +O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCc4ncccn4)cc3)cc12 +NS(=O)(=O)c1ccc(N2C(=O)c3c(Br)c(Br)c(Br)c(Br)c3C2=O)c(F)c1 +[C-]#[N+]c1ccc(Oc2ccc(-c3nc(NC(C)C(N)=O)cc(C(N)=O)n3)cc2)cc1 +OCC#Cc1cn2c(-c3ccc(-c4cnc(C5CC5)[nH]4)cc3)cnc2c(NCCC(F)(F)F)n1 +CC(C)c1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccccc2)nc2ccccn12 +C=CC(=O)Nc1ccccc1Nc1nc(Nc2ccnn2C)ncc1C +COc1cc2cncc(Cc3ccc4nc(C)ccc4c3)c2cc1OC +COc1ccc(C2CCCc3nc(SCc4c(F)cccc4Cl)n(-c4ccc(F)cc4)c32)cc1OC +Fc1ccccc1OC(CCN1CCN(c2noc3ccccc23)CC1)c1ccccc1 +COc1cccc(CNc2ccc(S(=O)(=O)Nc3cccc(C(C)(C)C)c3)cc2)c1O +CCc1c2c(nc3ccc4c(c13)N(C)CCO4)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC +Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(C(N)=O)cc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F +CCCCCCCCCCCCCCCNC(=O)OCC1OCC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1 +COc1cc2c(cc1N1CCN(C)CC1)N(S(=O)(=O)c1ccc3ccccc3c1)CCC2=O +O=S(=O)(c1ccccc1)C1CCN(CCc2ccccc2)CC1 +CN(C)Cc1cccc(C23CCC(N(CCCN4CCN(C)CC4)c4nc5cc(F)c(F)cc5[nH]4)CC2C3)c1 +CC(C)(C)OC(=O)N1CCCC1CNc1cc(Nc2cccc(Cl)c2)nc2c(C=C3NC(=O)NC3=O)cnn12 +CC(=O)N1CCc2nc(N3CCN(Cc4ccc(F)cc4F)CC3)c(NC3CC(F)C3)nc2C1 +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCCCc1ccc(O)c(O)c1 +O=C(O)CCC=C1CC2CC(O)C(C=NNC(=O)Nc3ccc(Cl)c(Cl)c3)C2C1 +CN1C(=O)c2c(nn(Cc3ccc(-c4ccccc4)cc3)c2Nc2ccccc2)N2CC(C3CCOC3)N=C12 +COc1cc(OC)cc(N2C3CCC2CC(c2cnc(N)nc2N)C3)c1 +CC1CCC2C(C)C(OCCNCCNc3ccnc4cc(Cl)ccc34)OC3OC4(C)CCC1C32OO4 +COc1cc(-c2cccc(OC(F)F)c2)c(F)cc1-n1c2c(ccc1=O)CN(S(=O)(=O)Nc1ccon1)CC2 +O=C(CCO)NC1CCC(CCN2CCC(c3noc4cc(F)c(F)cc34)CC2)CC1 +CCC(=O)N1CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C(NC(=O)c2nc3c(s2)CN(C)CC3)C1 +[C-]#[N+]c1cccc(S(=O)(=O)c2ccc3c(c2)c2c(n3C)CC3CCC2N3)c1 +O=S(=O)(NCCCCCN1CCN(c2ccc(Cl)cc2)CC1)c1cnc2ccccc2c1 +Cc1ccc(-c2cn(CCCCCn3cccc(O)c3=S)nn2)cc1 +c1ccc2c3c([nH]c2c1)C(C1CCCCC1)NC(c1nc(-c2ccncc2)c[nH]1)C3 +COc1cc(C=C2SC(=Nc3ccccc3)NC2=O)ccc1O +CCOc1ccc(-c2c(NC(=O)c3ccc(OC(C)C)cc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1 +O=C(NCC1CN(c2ccc(N3CCCCC3=O)c(F)c2)C(=O)O1)c1ccc(Cl)s1 +O=C(Nc1ccc(C(F)(F)F)nc1)Nc1ccc(C2CNCCO2)cc1F +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccc(Cl)s2)[nH]c1=O +CN(C)CCc1c[nH]c2ccc(-n3cnc4cccnc43)cc12 +O=C(Cc1cccs1)Nc1cccc(-c2nc3ccccc3[nH]2)c1 +O=C(O)c1ccc2c(c1)nc(-c1ccc(OCc3cccc(-c4ccccc4)c3)cc1)n2C1CCCCC1 +Cc1nn(Cc2ccc(-c3nc4cc(F)ccc4[nH]3)cc2)c(C)c1CC(=O)O +Cc1ccc(-c2nc(NN=Cc3ccccc3[N+](=O)[O-])c3ccccc3n2)cc1 +O=C(NC1CCc2cc(F)ccc2C1Cc1cccnc1)C1CCC(CNS(=O)(=O)c2ccccc2F)CC1 +CCCC[S+]([O-])c1sc2nc(-c3nccs3)cc(-c3ccc(CO)cc3)c2c1N +N#Cc1ncc2nc1OCCCCCOc1cc(CC(O)CO)c(Cl)cc1NC(=O)N2 +Cc1ccccc1C#CC1CC(CN2CCCCC2)C(=O)N1C +CS(=O)(=O)CCNCc1nc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cs1 +CCCCCn1c(C)c(C(=O)c2ccc(OC)c3ccccc23)c2ccccc21 +COc1ncc(-c2ccc3nccc(-c4ccc(CN(C)CCO)cc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +Cc1c(C)n(Cc2cccc(OC(C)(C)C(=O)O)c2)c2ccc(C(=O)NC(C)c3ccc(C(C)(C)C)cc3)cc12 +COc1cc2ncnc(Oc3cnn(CC(=O)Nc4ccc(N(C)C)cn4)c3)c2cc1OC +NC(Cc1ccc(O)cc1)C(=O)NCCCCCCCCNC(=O)C(N)Cc1ccc(O)cc1 +CC1CN(c2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)CCN1 +C(=CC1CCCN(CCCc2ccccc2)C1)c1ccccc1 +CN1CCN(c2cnc3c(NCCc4ccncc4)nc(-c4ccccc4)nc3n2)CC1 +O=C1CSC(c2c(F)cccc2F)N1c1cccc(Br)n1 +CC(C)n1c(Cn2nc(-c3cccc(O)c3)c3c(N)ncnc32)cc2ccccc2c1=O +CCN(C)c1nccc(N2CCC(Oc3ccc(C(C)NC(=O)c4sc(NC(C)=O)nc4C)cc3)C2)n1 +Cn1ccc(NC(=O)c2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)n1 +O=C(Nc1cc2[nH]nc(OCCO)c2cn1)NC(COC(F)F)c1ccccc1 +CC(C)(CCCOc1ccc(-c2ccc(Cl)cc2)cc1)CN1CCN(c2ccncc2)C1=O +CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1cc[nH]n1 +COc1cc2[nH]c(=S)n(Cc3ccncc3)c(=O)c2cc1-c1cnco1 +Oc1ccc(-c2nnc(-c3cc(O)c(O)cc3Br)s2)cc1O +Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCCCCCNc1c3c(nc4cc(Cl)ccc14)CCCC3)O2 +CC(=O)OCC1OC(n2c(Cl)nc3c(Cl)c(Cl)c(Cl)cc32)C(OC(C)=O)C1OC(C)=O +O=C(Nc1ccc(C(F)(F)F)c(Cl)c1)c1ccnn1CCc1ccncc1 +CC(C)OC(=O)C(C)NP(=O)(OCC1OC(n2ccc(=O)[nH]c2=O)C(C)(Cl)C1O)Oc1ccccc1 +CN(C(=O)C(C)(C)C)C1CCC(C(N)Cc2cc(F)ccc2F)CC1 +COc1cc(CC=Cc2ccccc2C=CC(=O)O)ccc1OCCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] +Cc1cc(Nc2ccc(Cl)c(Cl)c2)n2nc(C)nc2n1 +O=S(=O)(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(CCc2ccccc2)CC1 +CC(NC(=O)C1CC2C3CCc4cc(O)ccc4C3CCC2(C)C1O)c1ccccc1 +Cc1cc(Oc2ncccc2OC(F)(F)F)ccc1-c1c(C)c(=O)[nH]c(=O)n1C +CC(C)(C)c1ccc(-c2noc(C(=O)NNC(=S)Nc3ccc(C(F)(F)F)cc3)n2)cc1 +COc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)cn1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(C(=O)C2(C(F)(F)F)CC2)CC1 +COc1ccc2c(=O)c(C)c(-c3ccc(Cc4ccc(OC(F)(F)F)cc4)cc3)[nH]c2c1 +CC1CC(=O)NN=C1c1ccc(NC(=O)c2ccccc2C(F)(F)F)cc1 +CNC(=O)C(NC(=O)c1ccc(-c2cccc(CNC(=O)c3ccnc(Cl)c3)c2)o1)C1CCCCC1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1CCC(C(=O)O)CC1 +COc1ccc(-c2cccc3nc(Nc4ccc(C(=O)O)cc4)nn23)cc1 +NC(=O)NN=Cc1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +CCOc1cc(C(=O)C[n+]2nc(N)n3nc(OC(CC)CC)ccc32)cc(C(C)(C)C)c1OCC +O=C(CCCCCC(NC(=O)c1cc2ccccc2[nH]1)C(=O)NC1(Cc2ccccc2)CCCC1)NO +CCc1cn2c(NC(=O)C3CCCC3)nc(-c3ccccc3)nc2n1 +COc1cc(Nc2ncccc2-c2nc(Nc3ccc4c(c3)OCCO4)n(C)n2)cc(OC)c1 +Nc1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2(Cl)Cl)c(=O)n1 +O=C(NCc1ccccc1)N1CCC(CN2CCC(c3noc4cc(F)ccc34)CC2)CC1 +Nc1nc(-c2ccco2)c2cnn(Cc3c(F)cccc3F)c2n1 +CC(C)(C)C(=O)NC(CCCCN)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 +CC(C)(C)c1n[nH]c2nc(-c3ccccc3)c(C#N)c(-c3ccccc3)c12 +CCC(=NO)c1ccccc1NS(=O)(=O)c1ccc(OC(=O)C(C)(C)C)cc1 +COc1cc2ccn(CCn3cc(NC(=O)c4ncoc4-c4cccc(C)c4)cn3)c2cc1OC +CNc1nn2c(C)cc(CN)nc2c1S(=O)(=O)c1ccccc1 +O=C(Nc1cccc(F)c1)c1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2n1 +CCS(=O)(=O)N1CCN(c2ccc3cc2COCC=CCOCc2cccc(c2)-c2ccnc(n2)N3)CC1 +CN1CCC(c2n[nH]c3ccc(S(=O)(=O)c4ccc(F)cc4)cc23)CC1 +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5c(c4)CCO5)c3c2)C1 +NCCCCC(NC(=O)CN(CC1(c2ccccc2)CCCC1)C(=O)CCc1ccccc1)B(O)O +O=C(c1cccc(OC(F)(F)F)c1)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 +NC(CNC(=O)Nc1cc(S(=O)(=O)O)ccc1F)C(=O)O +NC(=O)c1ccccc1Nc1ccnc(Nc2ccc3ccccc3c2)c1 +CCCOC(=O)c1cccc(NC(=O)COc2ccccc2Cl)c1 +COc1cc(C(=O)NCc2ccc(Cl)cc2F)ccc1-c1cn[nH]c1 +CC(NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(-c3noc(-c4ccccc4)n3)c(F)c2)CC1 +CCC(Nc1ncnc2[nH]cnc12)c1cc2cccc(C)c2c(=O)n1-c1ccc(F)cc1 +CN(C)CC(=O)NC1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1 +Cc1ncc(C)n2nc(CCc3ccc4cc5c(cc4n3)OC(F)(F)O5)nc12 +Cc1nc(C)c(C(c2ccccc2)c2c[nH]cn2)s1 +Cc1cccc(COc2cc(-n3cnc4ccccc43)sc2C(N)=O)c1 +NS(=O)(=O)Oc1ccc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)cc1F +CC1CN(C(=O)c2ccccc2-n2nccn2)C(Cc2cccc(-c3ncccn3)c2)CO1 +COc1ccc(-c2cncc(C#N)c2Nc2cccc3[nH]ccc23)cc1OC +O=C1CN2Cc3cc(OCCCC(=O)N4CCCC5CCCCC54)ccc3N=C2N1 +CCC(=O)Nc1cc2c(Nc3ccc(Oc4ccc5c(c4)OCO5)cc3)ncnc2cc1OC +CN(C)CCN(C)C(=O)c1cccc(Cc2nnc(O)c3ccccc23)c1 +CN1C(=O)CC(c2ccccc2)C1C(O)c1ccc(-c2ccccc2)s1 +COc1cc(C=C(C(=O)N2CCC=CC2=O)c2ccc(C)cc2)cc(OC)c1OC +CCN(CC(N)=O)c1ccc(Br)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12 +COc1cc(C(CC(=O)c2ccc(C)cc2)Nc2ccc([N+](=O)[O-])cc2)cc(OC)c1OC +O=C1N(c2ccc(C#Cc3ccccc3)cn2)CC2CCCCN12 +COc1ccc2nc(-n3nc4c(c3O)-c3ccccc3CC4)sc2c1 +CC(Cc1ccc2c(=O)ccoc2c1)CN1CCN(c2ccccn2)CC1 +CC(C)(O)CC(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +C=CC(=O)NC1CCN(S(=O)(=O)c2ccc(C(=O)NC3CC3c3ccccc3)cc2)CC1 +COc1ccc(C(=O)NC2C(CC=CCCCC(=O)O)CC3CC2C3(C)C)cc1 +O=S(=O)(c1ccc(Cl)cc1)N(Cc1ccc(-c2cccc(Cl)c2)cc1)Cc1ccccn1 +Cc1cccc(C(=O)NC2(C(=O)O)Cc3ccccc3C2)c1OC1CCC1 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+Cc1ncccc1C#Cc1c(Cl)nc(N)nc1NC1CC(CO)C(O)C1O +N#Cc1cc(C(=O)NN=Cc2cccc3c2ccn3Cc2ccc(C(F)(F)F)cc2)ccc1O +CCCCc1nc2ccc(C)cc2c(=O)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCOC(=O)NC1CCC2C(C1)CC1C(=O)OC(C)C1C2C=Cc1ccc(-c2cccnc2)cn1 +Clc1cccc(Nc2cncc(-c3cncc(NCCCn4cncn4)c3)n2)c1 +CC(C)Oc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C(N)=O +CCOCC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(C(C)(C)C)cc1)C2 +O=C1NC(=O)C(CN2Cc3cc(Cl)ccc3C2=O)(c2ccc(F)cc2)N1 +Cc1c(CN(C)C(=O)C=Cc2cnc3c(c2)NCCC(=O)N3)[nH]c2ccccc12 +COc1cccc(OC)c1CNc1nc(NC2CCCCC2)nc2ccc(Cl)cc12 +CC(=O)OCC(Cc1ccccc1)NC(=O)C(NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C +O=C(NCC12CCC3(O1)C1Cc4ccc(O)cc4C3(CCN1CC1CC1)C2)c1ccccc1 +Cc1nc(C)c(-c2nnc(SCCCN3CCC4(c5ccc(C(F)(F)F)cc5)CC34)n2C)s1 +COc1cc(OC)c(C(=O)Nc2c[nH]nc2C(=O)NC2CCC(OC)CC2)c(OC)c1 +CC1CCC(CC(=O)N2Cc3ccccc3CC2C(=O)N2CCCC2)CC1 +CC(CCC(O)C(C)(C)O)C1CCC2(C)C3CCC4C(C)C(O)CCC45CC35CCC12C +COc1cc(NC(=O)c2ccccc2F)ccc1-c1nnc(NCCCCN2CCCCC2)o1 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+CC(C)CC(CC(=O)NO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCS(C)(=O)=O +Cc1cc(-c2ccc(OCCCN3CCCC3C)cc2)n[nH]c1=O +CCCCC(NC(=O)NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)C(=O)O +N#Cc1cnc(NCC(F)(F)c2ccccn2)c(=O)n1CC(=O)NCc1ncccc1F +O=C(CC1CCCCC1)c1ccc(OC(F)F)c(OC2CCOC2)c1 +CCOc1ccc(-c2cn3c([n+]2-c2ccccc2)CCCCC3)cc1 +CCCN(CC=CC(C)=CC(=O)O)c1cc(C(C)(C)C)cc(C(C)(C)C)c1 +N#Cc1ncc2nc1OCCCCCOc1cc(OCC(O)CO)c(Cl)cc1NC(=O)N2 +CC(Nc1nc(N)nc(NCCc2ccccc2)n1)c1ccc(F)cc1 +O=C(NCC1CCN(c2ccncc2)CC1)c1cc2ccccc2n1Cc1cc(-c2ccc(Cl)s2)on1 +Cc1cc(NCCc2c(C)n[nH]c2C)n2nc(NC(C)c3cccc(Cl)c3)nc2n1 +NC(=O)c1cc(Cl)c2c(Cl)c(I)n(C3CCCC(N)C3)c2n1 +CCCC(=O)N1CC(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)C1 +CN(c1ccc2c(c1)Cc1c(-c3ccoc3)n[nH]c1-2)C1CCC(O)CC1 +O=C(N1CCCCC1c1ccccc1)n1cc(-c2ccc(-c3cccc(CO)c3)cc2)nn1 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NS(=O)(=O)C(C)C)CC2 +Cn1nc(C(F)(F)F)cc1-c1cc(C(N)=O)c2[nH]c3cc(C(=O)N4CCOCC4)ccc3c2n1 +CC1CCC(COc2ccc(F)cn2)CN1C(=O)c1c(F)cccc1-c1ncccn1 +COc1ccc2[nH]cc(CCNC(=O)CCCCCNc3c4c(nc5cc(Cl)ccc35)CCCC4)c2c1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccccc1OCCO +O=C(O)CCCSCCN1C(=O)SCC1C=CC(O)Cc1cccc(F)c1 +CCn1ncc2c3c(NCc4ccc(OC)c(Cl)c4)nnc(-n4cnc(C(=O)NC)c4)c3cnc21 +Cc1c(CC(N)=O)c2cc(OCCCC(=O)O)ccc2n1Cc1ccccc1 +COc1cccc(-c2cc(=O)c3cc(Cl)cc(NCCCO)c3o2)c1N +COCCCn1cc(C)c2cnc(C(C)N(C(=O)C3CNCCO3)C3CC3)cc21 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(OCC(C)C)C(=O)O)c2sccc12 +Cc1ccc(NC(=O)C(COC(C)C)Oc2ncnc3c2cnn3-c2ncccc2Cl)nc1 +NC1CCC(NC(=O)c2ccnc3nc(-c4cccs4)[nH]c23)CC1 +COc1cc(C(C)=O)ccc1OCCCN1CCC(C(c2ccc(F)cc2)C2CCCCC2)CC1 +CC(C)(C)NC(=O)C1CCCCN1CC(O)CC(Cc1ccccc1)C(=O)NC1c2ccccc2CC1O +O=C(NC1CC1)c1ccc(F)c(CCc2cnc(Nc3ccccn3)s2)c1 +O=C1C(=Cc2ccc(N3CCN(C(c4ccccc4)c4ccccc4)CC3)cc2)C(=O)c2ccccc21 +O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(Cl)nc1C(F)(F)F +Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(-n3cncc3C)ccc12 +CCCCCCCC(=O)Nc1onc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OC)cc1 +OC1(c2ccc(Cl)cc2)c2ccc3ccccc3c2C2=NCCN21 +N#CC(Cc1ccc(-c2ccc3c(c2)C(=O)NC3)cc1)NC(=O)C1NC2CCC1C2 +O=C(c1ccc(F)cc1-c1ncccn1)N1CC2CC(Oc3ccc(C(F)(F)F)cn3)C1C2 +CCc1cc(-c2ccccc2)cc(CC)[n+]1CC(=O)Nc1nccc(Nc2ccc(S(N)(=O)=O)cc2)n1 +CNc1ccc(-c2cc(=O)c3cc(OCCOCCOCCF)ccc3o2)cc1 +COc1c(O)c(CN2CCCC2CO)c2c(c1O)C1OC(CO)C(O)C(O)C1OC2=O +CCCOc1c(CN(C)C(=O)C=Cc2cnc3c(c2)CC2(CCNCC2)C(=O)N3)cccc1OC +O=C(OC1CN2CCC1CC2)c1cc(Cl)cc2nc[nH]c12 +O=C1NC(=O)c2c1c(-c1c(Br)cccc1Br)cc1[nH]c3ccc(O)cc3c21 +COc1cccc(C=C2SC(=Nc3ccccc3)NC2=O)c1OC +NC(=O)c1cnc(Nc2ccc(CCO)cc2)nc1NCc1ccccc1 +CC(C)C1NCCOc2ccccc2C=CCNC(=O)C(Cc2ccccc2)NC(=O)C2(Cc3ccccc3C2)NC1=O +NC(=O)c1ccc2c(c1)nc(NCc1ccccc1Cl)n2CC1CCCCCC1O +CC(C)C1CCC(N2CCC(C(N)=O)(c3ccccc3F)CC2)CC1 +NC(=O)c1cc(I)ccc1NC(=O)C=Cc1ccccc1 +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3ccccc3Cl)c3ccccc32)CC1 +Nc1c2c(nc3c1cc(-c1ccccc1)n3-c1ccccc1)CCCC2 +CCC12CCC(O)CC1=CCC1C2CCC2(C)C(O)CCC12 +CN(C(=O)Cc1cccc2ccccc12)C1CCC2(CCCO2)CC1N1CCCC1 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(CN5CCC(O)C5)CC4)cc2)CC3)cc1 +COc1ccc(OC)c(C(=O)CCCCN2CCC3(CC2)NC(=O)NC3=O)c1 +CC(C)N1C2C=C(c3cnc(NCc4ccc5c(c4)OCC5)c(C(=O)NCC4COc5ccccc5O4)c3)CC1CC2 +O=C(NC1CCC(CCN2CCC(c3cccc4c3CCO4)CC2)CC1)C1(O)CC1 +CCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OC +CCCC(CC(=O)O)n1ccc2cc(NC(=O)Cc3ccc4c(n3)NCCC4)ccc21 +Cc1c(F)cc(C(=O)NC2CC2)cc1-c1cc2cnn(-c3c(F)cccc3F)c2n(C)c1=O +NC1CN(c2nccc(-c3ccccc3)n2)CC1c1ccc(Cl)cc1Cl +CN(C)Cc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 +CN1C(=O)C(c2ccc(C#Cc3ccccc3)nn2)CC1(C)C +O=C(O)CCNC(=O)C1CCCCN(C(=O)CCC2CCNCC2)C1 +COc1ccc(-c2ccc[nH]2)c(C(=O)c2cc(OC)c(OC)c(OC)c2)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c4c(ccc3nc2-1)OCN(c1ccc(C)cc1)C4 +CC(C)(NC(=O)c1ccc2c(=O)c3ccccc3[nH]c2c1)c1cccnc1 +Brc1sc2nccc(N3CCC(COCCN4CCCC4)CC3)c2c1-c1ccccc1 +CCCNCC(=O)Nc1c(C)[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c1C +COc1cc2c(cc1OC)-c1c(-c3cccc(Br)c3)ncn1CC2 +COc1c(CNC2CCC(NS(C)(=O)=O)CC2)cc(-c2ccc[nH]c2=O)cc1C(C)(C)C +CNC(=O)c1ccc(-c2cc3c(NC4CC5CN(C(=O)C(C)(C)O)CC5C4C)c(C(N)=O)cnn3c2)cn1 +CS(=O)(=O)c1ccc(-c2cccc(-n3cc(C(=O)NC4CC4)c(=O)c4cccnc43)c2)cn1 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+COc1cc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)ccn1 +COc1cc(OC)c2c3c(n(S(=O)(=O)c4ccc(N)cc4)c2c1)CCCC3 +Cc1nn(C)cc1-c1cccc2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC(F)(F)F)cc12 +C#CCOc1cc2c(Nc3cccc(Cl)c3)ncnc2cc1OC +Cc1cc(C)c(CNC(=O)c2cc(Br)nc3c2cnn3C(C)C)c(=O)[nH]1 +N=C(N)c1cccc(COc2c(Cl)cc(C(=N)N)cc2Cl)c1 +COC(=O)C1C(c2ccccc2)CC2CCC1N2CC#CCF +Cc1c(Cc2c(F)cccc2Cl)nc(SCC(=O)c2ccc(F)cc2)[nH]c1=O +O=C(CN1CCC(NC(=O)c2ccccc2)C1)NC1CCc2cc(F)ccc2C1Cc1cccnc1 +O=C1NC(=O)C(c2ccc(Oc3ccccc3)cc2)(N(CCO[N+](=O)[O-])CCO[N+](=O)[O-])C(=O)N1 +Cc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)NS(=O)(=O)C1CC1)n2Cc1ccccc1F +CN1CCc2c(c3cc(C(C)(C)C)ccc3n2Cc2ccc(C(=O)NO)cc2)C1 +Cc1[nH]c(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)OC(=O)NC2CCCCC2)nc1C(=O)O +Cn1cc(-c2cc(NS(C)(=O)=O)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +COC1Cc2ccccc2C2(CCCN(CCCc3ccccc3)C2)O1 +Cc1ccc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NC2CCN(CC(C)(C)C)CC2(C)C)cc1 +CN(C)CCCNC(=O)c1ccc2c(c1)CC(c1nc3ccc(-c4ccnc(N)n4)cc3[nH]1)CO2 +O=C1c2ccccc2CCCC1CCN1CCC(Oc2ccccc2)CC1 +O=C1COc2ccccc2N1CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1 +O=C(O)c1cccc2c3c(n(Cc4ccc(F)cc4)c12)CCCC3 +COCc1cc(Nc2cccc(Cl)c2)nc(-c2ccccn2)n1 +COc1cc(Nc2c(C#N)cnc3cc4c(cc23)ncn4CCN2CCOCC2)c(C)cc1Cl +Cc1cccc(OCC(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)c1 +Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4cccnc4)c3Cl)c2n1 +Oc1c2c(nc3cc(-c4ccc(Br)cc4)nn13)CCCC2 +CCC(O)(c1cn(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)cn1)C(F)(F)F +Cc1nnc(-c2ccc(-c3cc(NC(=O)c4ccc(CN5CCN(C)CC5)cc4)ccc3C)c(C)c2)o1 +CNC(=O)c1cc(-c2ccnc(C)c2C#Cc2ccc(C)nc2)ccc1Cl +CN(C)CCNC(=O)c1ccc(-c2nn(C)c(=NC3CCCCC3)s2)cc1 +FC(F)(F)c1ccccc1-c1cc(Cl)c2[nH]c(C3=NOC4(CCCCC4)C3)nc2c1 +CC(C)NC(=O)c1cn(-c2cccc(Br)c2)c2ncccc2c1=O +Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCC(CO)CC2)n1 +O=C(c1ccco1)N1CCN(c2cnn(CCN3CCN(c4ccccc4Cl)CC3)c(=O)c2Cl)CC1 +C(#Cc1ccccc1)CNC1CCN(Cc2ccccc2)CC1 +Cc1cc2ncc(-c3ccc4cc(CCN5CCCC5C)ccc4n3)c(C)n2n1 +COc1ccccc1N1CCN(CCSc2nc3ccccc3[nH]2)CC1 +COc1ccc2c(c1)[n+]([O-])nc(NCOC(C)c1ccccc1)[n+]2[O-] 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+CCN(CC)CCNc1ccc(CNS(C)(=O)=O)c2sc3ccccc3c(=O)c12 +CCCCc1ccc(N(CC(=O)O)C(=O)C(C)CSC(C)=O)cc1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccsc2)cc1 +CC(C)CCC(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4(O)CC(O)C(O)CC4(C)C3C(O)CC12C +CC(NC(=O)Nc1cc2[nH]nc(C3CC3C(=O)O)c2cn1)c1ccccc1 +CC(C)NCC(Cc1ccc(F)c(F)c1)C(=O)N1CCN(c2ncnc3c2C(C)SC3)CC1 +Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)N(Cc2ccccc2)Cc2cccnc2)cc1 +Clc1ccccc1CC1=NC(c2ccccc2)C(c2ccccc2)N1 +CC(Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNCCCO)cc1Cl +CC(C)Cc1sc2ccccc2c1C(=O)c1cccc2ccccc12 +CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)nc(OC3CCCCCC3)n2)cc1 +CN(C)C12CC(c3ccccc3)C(CN(CCN3CCCC3)C1)C(c1ccccc1)C2 +Cc1ccc2[nH]c(O)c(C3=Nc4ccccc4C3=O)c2c1 +COc1c(I)cc(I)cc1C(=O)Nc1ccc2ccccc2c1 +O=S(=O)(Nc1ccncn1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1Br +CC1(c2cccc3ccccc23)C(=O)N(CCCn2ccnc2)C(=O)N1Cc1ccccc1C#N +COc1cc(-n2ccnc(NCCc3ccccc3)c2=O)ccc1OCCN1CCCC1 +N=C(CCSCC(=N)SC(=N)NC(=O)C(O)c1ccccc1)SC(=N)NC(=O)C(O)c1ccccc1 +COc1ccc2c(c1)c(=O)c1c(NCCc3ccccc3)ccc3nnn2c31 +Cc1cc(C)c(C=C2C(=O)Nc3ccc(-c4cnc5ccccc5n4)cc32)[nH]1 +COc1ccc2c(c1)NC(=O)CN2c1nc(N2CCC(F)(F)C2)nc2ccccc12 +Cc1cc(N2CCCC2)nc2ccc(NC(=S)NCCCN3CCN(Cc4ccccc4)CC3)cc12 +O=C(Nc1cccc2c(=O)cc(C(=O)O)oc12)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 +COc1ccc(S(=O)(=O)N2CCCC2C(=O)Nc2cc(C)cc(C)c2)cc1 +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2cccc(Cl)c2)c2ccc(Cl)c(Cl)c2)CC1 +Cc1cccc(S(=O)(=O)c2sc3ncccc3c2-c2ccc(Cl)cc2)c1 +CN(Cc1nc2cccc(C(=O)NCCCCN)c2[nH]1)C1CCCc2cccnc21 +COc1ccc(CNC(=O)c2ccc(OC)c(OC3CCCC3)c2)cc1 +COc1ccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2C(N)=O)cc1NS(N)(=O)=O +CC(CO)OC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)nc3c2C(=O)N(C)CC(C)(C)O3)cc1 +Nc1c(C(=O)Nc2ccccc2F)sc2nc3c(cc12)C(=O)CCC3 +O=S(=O)(C1CCCCC1)N1CCN(C(c2ccc(Cl)cc2)c2cncnc2)CC1 +CC1=CC(C)(C)C2(O)COC(c3ccc(O)cc3)C1C2 +CCOC(=O)C1(Cc2ccccc2)CCCN(C(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)C1 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)c3cc(Cl)ccn3)cc12 +COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2cccc(C3(C(=O)O)CCCC3)c2)n1 +CCNc1nc2ccc(OC)cc2cc1Cc1c(=O)[nH]c(C(C)C)c2cc(OC)c(OC)cc12 +O=c1cc(-c2ccccc2)oc2c(Br)c(O)c(Br)c(O)c12 +CC1(COc2ccc3c(c2)C2(COC(N)=N2)c2cc(-c4cncnc4)ccc2O3)COC1 +CC(C)(C)C(=O)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +CCN(CC)CCCC(C)(C)Nc1c2ccccc2nc2ccccc12 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CNCC(O)C(Cc1ccccc1)NC(=O)C1(O)COCC1(C)C +N#CC(c1cccnc1)N1CCN(CCC(c2ccccc2)c2ccccc2)CC1 +COc1ccccc1N1CCN(Cc2ccc3c(c2)COC3(CCCN(C)C)c2ccc(F)cc2)CC1 +CC(C)(C)c1ccc(C=CC(=O)Nc2ccc3c(c2)OCCO3)c(Br)c1 +O=C(Nc1ccc(C(=O)N2CC3COCC3C2)cc1)N1Cc2ccc(F)cc2C1 +Cc1noc(C)c1-c1ccc2c(c1)C(c1ccsc1)(N1CCC(O)CC1)C(=O)N2 +N=C(N)NS(=O)(=O)c1ccc([N+](=O)[O-])cc1 +Cc1cc(OCc2ccc(-c3ccccc3C(=O)O)cc2)c2ccccc2n1 +O=C(NCCCCN1CCN(c2ccccc2OCCF)CC1)c1ccc(OCCOCCOCCF)cc1 +Cc1ccc(Cn2cc3c(=O)n(C)c(=O)n(CC(C)C)c3c2)cc1 +C[N+]1(C)CCOC(O)(c2ccc(-c3ccc(C4(O)C[N+](C)(C)CCO4)cc3)cc2)C1 +COc1cc(C(=O)NCc2cccc(N(C)C(C)=O)c2)ccc1-c1cn[nH]c1 +CC(CCC(=O)NCCc1ccc(S(N)(=O)=O)cc1)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C +CC1C2Cc3ccc(Br)cc3C1(C)CCN2Cc1ccccc1 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+CC(NP(=O)(OCC1OC(n2ccc(=O)[nH]c2=O)C(C)(N)C1O)Oc1ccccc1)C(=O)OC1CCCC1 +CN(C(=O)CCC(=O)Nc1nccs1)C(CN1CCC(O)C1)c1ccccc1 +CCCn1c(=O)c2nc(C3CCC(C(=O)NCCN(C)C)CC3)[nH]c2n(CCC)c1=O +O=C(Nc1cc[nH]c(=O)c1)c1cc(OC(F)(F)F)ccc1Oc1ccc(F)cc1 +CCCCC1=C(c2ccc(CCc3ccccc3)cc2)N2CCCN=C2c2ccccc21 +CC(C)CCNC1=NC(=Cc2ccc3c(c2)OCO3)C(=O)N1C +NC(=NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccc(F)cc1F +CCc1nsc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4ccnc(N)c34)cc2)n1 +O=C(c1ccc(C#Cc2ccccc2)nc1)N1CCOCC1 +CCOc1ccc2c(c1)OC1=C(C(=O)CC(C)(C)C1)C2C1=C(O)CC(C)(C)CC1=O +COc1cc(C(F)F)c(C2CC2)cc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CN(C)C1CCCN(c2ccnc(-c3c[nH]c4ccc(-c5nnc(N)o5)cc34)n2)C1 +c1ccc2c(c1)CCN(Cc1ccc(OCCCN3CCCCC3)cc1)C2 +CC(C)N(CCNC(=O)C1c2ccc(Oc3cccc(F)c3)cc2CCN1C(=O)OC(C)(C)C)C(C)C +O=C(NCc1ccc(Br)cc1)C1C(C(=O)NC2CCNCC2)C2C=CC1C21CC1 +CCCCCc1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C#N)C(=O)N2)cc1 +COc1cc2ncc3c(c2cc1-c1cnc2ccccc2c1)n(-c1ccc(C#N)cc1F)c(=O)n3C +O=C(C1CCCN1C(=O)CC1CCc2ccccc2C1)N1CCSC1 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+Fc1cnc(Cl)nc1NCc1ccc(CNc2ccnc(NCCN3CCOCC3)n2)cc1 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cc2)cc1C#Cc1ccc(N)nn1 +COCCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(CCN5CCOCC5)c4)cc2)CC3)n1 +O=C(O)c1cncc(C2CC2c2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C3CC3)cc2Cl)c1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCn4c(cnc4C)C3)[nH]c12 +O=C(NCC1CCCCO1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +NC(=O)C1CCCN1C(=O)CCCNC(=O)c1ccc(F)cc1 +CC1Nc2ccc(-c3ccc(C#N)s3)cc2C(C)(C)O1 +CC(=O)c1ccc(Oc2ccc(-c3ccc(-c4ccccc4Cl)n3CC(=O)NC(=N)N)cc2)cc1 +NC1=NC(c2ccc(OC(F)(F)F)cc2)(c2cccc(-c3cccnc3F)c2)C2=NCCN12 +CN(C)c1cc(N2CCNCC2)ccc1S(=O)(=O)c1ccccc1 +CC(C)CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)C(O)C(O)C1O +CCNC(=O)c1cn2cc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)c2n1 +Nc1ncnc2c1c(-c1ccc3ncccc3c1)nn2CC1CCNCC1 +CC(C)Oc1ccc(-c2cc(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1 +Cc1ccc(CSCC(CO)NC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cc1 +Nc1cccc(-c2cc(-c3c(-c4ccc(O)cc4)n[nH]c3N)ccc2O)c1 +CN1C2COCC1CC(OC(=O)c1cn(CC(F)F)c3ncccc13)C2 +CN1CCN(CCCN(c2nc3cc(F)c(F)cc3[nH]2)C2CCC3(c4cccc(C#N)c4)CC23)CC1 +CC(C)N(C(=O)C1CCC2C3CCc4c(ccc(C(=O)O)c4C#N)C3CCC12C)C(C)C +O=c1c2cc(F)ccc2nc(C=Cc2ccccn2)n1-c1ccccc1Br +CC(C)N(C(=O)C1CCC2C3CC=C4C=C(C(=O)O)CCC4C3CCC12C)C(C)C +CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCN(C2CCN(C(=O)OCC)CC2)CC1 +Cc1ccc(C(=O)NC2CC2)cc1Nc1ncnn2cc(C(=O)c3c[nH]c4ccccc34)c(C)c12 +CN1CCC=C(c2nsnc2OCCCCNCCCCCNc2c3c(nc4ccccc24)CCCC3)C1 +CCc1cccc(CC)c1NC(=O)c1nn(C)c2c1CCc1cnc(Nc3ccccc3OC)nc1-2 +COc1ncc(NC(=O)c2ccc(Cl)cn2)cc1C1(C)CC(C(F)(F)F)OC(N)=N1 +O=C1NCCN1CCCN1CCN(C2CC(c3ccc(F)cc3)c3cc(Cl)ccc32)CC1 +O=C(NC(Cc1ccccc1)c1ccccc1)C(c1ccccc1)c1ccccc1 +CCOC(=O)C1=c2sc(=Cc3ccco3)c(=O)n2C(N)=C(C#N)C1c1ccco1 +CN1CCN(CCCNc2cc3nc(NC(=O)NC(C)(C)C)c(-c4c(Cl)cccc4Cl)cc3cn2)CC1 +O=c1[nH]nc2c3c([nH]c4cccc1c43)CC(c1ccccc1)C2 +CCCCCCCCN(C)C(=O)Cn1cc(Cc2cnc(OCC)nc2)c(=O)nc1SCc1ccc(F)cc1 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1Cc1cccc(OC)c1 +O=C(c1cccs1)c1cnn2c(-c3cccc(NC(=O)C4CCC4)c3)ccnc12 +CNC(=O)CNc1nc(-c2ccccn2)nc2scc(-c3ccccc3)c12 +CCOc1cc(C(=O)Nc2ncc(C)s2)ccc1-c1nc(C2CCC3CCC(=O)N3C2)n2c(Cl)cnc(N)c12 +CC(C)C(NC1=NS(=O)(=O)N=C1Nc1cccc(C(=O)N(C)C)c1O)c1cccc(F)c1 +O=C(NCC(c1cnc(C(F)(F)F)nc1)C1CCOCC1)c1c(F)cccc1Cl +COc1ccc2c(c1)CCCC2CCCCN1CCC(C)(C)CC1 +Cc1ccccc1C(CC(=O)O)NC(=O)c1cc(=O)n(-c2ccccc2)[nH]1 +Cc1nc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(N)c3ccccc3)c2=O)cs1 +N=C(N)NCCCC(N)COP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1O +CC(C)(C)N1CCC(Oc2cc(-c3ccc(F)cc3Cl)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c2)CC1 +Cc1onc(-c2ccccc2Cl)c1C(=O)N(C)c1cccc(F)c1 +O=C(Nc1cc(-c2ccccn2)nn1CC(F)(F)F)c1nc(C2CC2)ccc1Nc1cncnc1 +CC#CC(CC(=O)O)c1ccc(OCc2cccc(CN(C)Cc3ccsc3)c2)cc1 +COc1cc(C)c(C(=O)NS(=O)(=O)c2ccccc2)cc1-c1ccc(C#CCO)s1 +O=C(c1ccc(F)cc1)C1CCN(CCc2ccc(I)cc2)CC1 +CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 +CNC(=O)c1c(NC(=O)c2nc(C(C)C)cnc2Nc2cncnc2)cnn1C +Cc1cc(C)cc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(C)cc2Br)c1 +O=C1Nc2cc(-c3ccc(O)cc3)ccc2C1=Cc1ccc(C(=O)NCCN2CCCC2)[se]1 +CCNc1nc2ccccn2c(=N)c1S(=O)(=O)c1ccccc1 +COC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1ccccc1 +CC(c1cc2c3c(c1)CCN3C(=O)CC2)(n1ccnc1)n1ccnc1 +CC1CN2c3c(cc4c(C(=O)NCC(F)F)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CCn1c(O)cn(-c2ccc(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)cc2)c1=O +NC(CC(=O)N1CCc2c(C3CC3)n[nH]c2C1)Cc1cc(F)ccc1F +NCCCC(Cc1cn(C2CCC(Oc3ccccc3)CC2)cn1)C(=O)O +CCNC(=O)c1noc2c1CN(C(=O)c1cc(C(C)C)c(OC(C)=O)cc1OC(C)=O)CC2 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(OC(F)(F)F)c(F)c2)c1 +CN1C(=O)C(c2ncc(C#Cc3ccc(F)cc3)cn2)CCC1(C)C +O=C(c1cccc2ccccc12)N1CCC2(CC1)NC(=O)N(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C2=O +Cn1c(C(=O)NCC(F)(F)F)nc2c(N3CCC(n4c(=O)[nH]c5ncccc54)CC3)ncnc21 +COc1ccc(F)c(CN2CCN(C3CCC(O)(c4ccc5c(c4)OCO5)CC3)CC2)c1 +CC(C)c1cccc(C(C)C)c1NC(=O)CC(=O)CC(c1ccccc1)c1ccccc1 +Oc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CCCCc1nc(C)n(Cc2ccccc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCCC(NC(=O)c1nccs1)c1cnc(Nc2cnc(C)nc2)c(Cl)c1 +CC=C1C(O)CC2C3CCC4CC(N5CCCC5)CCC4(C)C3CCC12C +Cc1ncccc1N1CC(C(=O)NCc2ccc(F)c(F)c2Cl)N(C)C1=O +CCc1c2c(n(C)c1CC)CCCC2=NOC(=O)Nc1ccccc1 +CC1OC(=O)C2(N)CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4-c4nnn[nH]4)cn3)C12 +Cc1cccc(-c2nc3ccc(C)cn3c2NCc2ccccc2)c1 +Fc1ccc(Oc2cncc3sc(-c4nnn[nH]4)cc23)cc1 +CNc1cnc(-c2ccc(C3(c4noc(-c5cnn(C6COC6)c5)n4)CCC3)cn2)cn1 +O=C1NCC2(CCNCC2)c2[nH]c(-c3ccnc(-c4cnc5ccccc5c4)n3)cc21 +Cc1cc(C)nc(SCC(=O)c2ccc(S(N)(=O)=O)cc2)n1 +O=c1cc(Cn2ccnc2)c2ccc(OCc3cccc(OC(F)(F)F)c3)cc2o1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CCC2)C1c1ccc(C#N)cc1C1=CCNCC1 +CC(C)(C)C(=O)OCOP(=O)(CC=CCn1cnc2c(=O)[nH]c(N)nc21)OCOC(=O)C(C)(C)C +CC(C)Oc1nc(-c2cccnc2)nc2c1CN(c1nc3ccccc3o1)CC2 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C4COC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1C +COc1ccc(-c2nnnn2-c2cc(OC)c(OC)c(OC)c2)cc1F +NC(=O)c1cc(N2CCOC(C(N)=O)C2)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +CCC1CN(CC(F)(F)F)c2cc3c(C(F)(F)F)cc(=O)[nH]c3cc2O1 +O=C(NCCCNc1nc2ccccc2[nH]1)c1cccc(OC(F)(F)F)c1 +COc1ccc(C(Cc2ccncc2)c2ccc(NS(=O)(=O)Cc3ccccc3)cc2)cc1OC1CCCC1 +O=C1c2ccccc2C(=O)c2c1c(O)c1[nH]cc(CNC3CCNC3)c1c2O +CC1(C)CC(=O)C2=C(C1)Nc1c(O)cccc1N(C(=O)c1cscn1)C2c1ccc(OCc2ccccc2)cc1F 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+CC(C)CC(CO)Nc1nc(SCc2ccccc2Cl)nc2nc(N)sc12 +CCc1ccc(C(Nc2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)c2nnnn2C(C)(C)C)cc1 +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ON=C(C)C(F)(F)F +COc1cc2c(cc1OC)-c1c(-c3ccccc3)ncn1CC2 +COC1CC2CC(OC(c3ccc(F)cc3)c3ccc(F)cc3)CC1N2C +CCCC(=O)N1CCCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)C1 +CC(C)CN(NC(=O)C1CCC(=O)CC1)c1nc(C#N)ncc1Br +N=C(N)c1ccc(Nc2nc3cc(C(F)(F)F)ccc3[nH]2)cc1 +Cc1c(Cl)c(=O)oc2cc(OCc3ccccc3)ccc12 +O=C(O)COc1ccc(-c2nccs2)cc1-c1ccccc1 +CC(C)(C(=O)Nc1cnc2ccccc2c1)S(=O)(=O)c1ccc(Cl)cc1 +O=C(NCC(c1ccc(C(F)F)nc1)N1CCC(F)(F)CC1)c1c(Cl)cccc1Cl +Cc1cccc(NC(=O)c2cc(C)n(-c3cccc(C(F)(F)F)c3)n2)c1 +O=C1NCN(c2ccccc2)C12CCN(C1CCCCC1(O)c1ccccc1)CC2 +Cc1cc(NC(=O)c2cc(Cl)cc(Cl)c2)ccc1N1CCC(N2CCCC2C)C1 +N#CC1CCCN1C(=O)C(N)CC(=O)N1CCN(C(=O)c2ccccc2)CC1 +Cc1c(NCCN(C)C)cc(Cl)cc1N1CCN(c2ncnc3[nH]nc(C(F)(F)F)c23)CC1 +O=C(O)CC1COc2cc3c(cc21)OCC(c1cccc(-c2ccccc2)c1)O3 +O=C(NCCO)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 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+CC(=NOCC(O)CO)c1ccc2nnc(Cc3ccc4ncccc4c3)n2n1 +COc1ccccc1N1CCN(C(=O)CCCCSc2nnc3c4cc(F)ccc4n(Cc4ccc(F)cc4)c3n2)CC1 +CS(=O)(=O)c1ccc(-c2noc(C(CCO)C(N)C(=O)N3CCC(F)C3)n2)c(Cl)c1 +CCNc1nc(Nc2ccc(C(=O)N3CCOCC3)c(F)c2OC)ncc1C(F)(F)F +Oc1nc2cc(Br)ccc2n1C1CCN(CC2COc3ccccc3O2)CC1 +CCN(CCn1ccc(-c2ccc(F)cn2)n1)C(=O)c1cc(C)ccc1-c1ncccn1 +CC1CCCCN1c1ccc(-c2nc(-c3ccc4c(c3)CN(CC(=O)O)CC4)no2)cc1C(F)(F)F +CN1CCC(c2ccc(Cl)cc2)C(C(=O)OCCC(c2ccccc2)c2ccccc2)C1 +COc1ccc(-c2nc3c4cn(CCc5ccccc5)nc4nc(N)n3n2)cc1 +N#Cc1ccc2c(C#N)c(O)nc(SCc3ccccc3Cl)c2c1 +CC(=O)SCCCCCC(NC(=O)C1CCCC(=O)N1)C(=O)Nc1ccccc1 +CN1CCN(C2CCN(c3cccc(Nc4nc5c(-c6ccc(S(C)(=O)=O)cc6)cccn5n4)c3)CC2)CC1 +NC1(CN(C(=O)C2CC2c2ccccc2)c2ccc(-c3ccccc3)cc2)CCCC1 +COc1cccc(C(CO)n2ccc(-c3ccnc(NC4CCOCC4)n3)cc2=O)c1 +Cn1cnc(S(=O)(=O)NC(=O)c2cc(Cl)c(OCC34CC5CC(CC(C5)C3)C4)cc2F)c1 +COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NC2CCc3ccccc32)cc1F +c1ccc2cc(Cn3cc(CCCCc4cn(Cc5ccc6ccccc6c5)nn4)nn3)ccc2c1 +O=C(NCCc1ccc(S(=O)(=O)c2ccccc2)cc1)c1cc2cnccc2[nH]1 +CC(C)(C)c1ccc(C(=O)NC2CCC(CCN3CCN(c4nccc5c4CCO5)CC3)CC2)cc1 +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccc(F)c(F)c3)sc12 +COc1cc(OC2CCNCC2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +CC(=CC(=O)NC(C(=O)N1CCCC1C=CCCc1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 +CC(C)(C)c1cc(NC(=O)C2CCCCN2C(=O)N2CC[S+]([O-])CC2)no1 +NC(=O)C1CCCN1C(=O)CCCCCN1CCN(c2ccccc2Cl)CC1 +COc1cc(C=CC=CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O +O=C(OC1C[N+]2(Cc3csc(-c4ccccc4)n3)CCC1CC2)C1(C2=CC=CC2)CCCCCC1 +COC(CN1CCC2(CC1)CC(=O)N(C1=CC(=O)OC1)C2)c1ccc2c(c1C)COC2=O +CC(C)(Nc1ccc(Cl)c(C(=O)NCC(N)=O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 +COCCc1ccc(OCC(O)CNC(C)(C)CSc2ccccc2C)cc1 +O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCCN3CCCCC3)ccc2[nH]1 +O=C(Nc1ccccc1)N(Cc1ccc(Br)cc1O)c1cc(-c2ccccc2)[nH]n1 +CCc1cc(-c2ccc(C(N)=O)c(N)c2)c2cccc(-c3cnc4ccccc4c3)c2n1 +CC(C)(N)c1ccc(N2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)nc1 +O=C(c1ccc(-c2ccc(=O)n(-c3ccc(F)cc3)n2)cc1)N1CCCC1CN1CCCC1 +CN1CCN(CCNC(=O)c2c(C(N)=O)nc3n2CCOc2cc(F)c(C#CC(C)(C)O)cc2-3)CC1 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+COc1cc(C=C2SC(=O)NC2=O)ccc1Oc1ccc([N+](=O)[O-])c(C(F)(F)F)c1 +CCOc1cc2ncnc(C#Cc3[nH]ccc3-c3ccccc3)c2cc1OCC +CCCc1n[nH]c2c1C(c1ccc(Cl)cc1)c1c(nc3c(c1N)CSCC3)O2 +O=C(CO)NC1CCC(CCN2CCC(c3noc4cc(Cl)ccc34)CC2)CC1 +C=CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)nc1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1ccc(Cl)cc1 +Cc1ccc(NC2=C(Cl)C(=O)c3ncncc3C2=O)cc1C +COc1ccc(CN(C(CC(C)C)C(N)=O)S(=O)(=O)c2ccc(F)cc2)cc1F +COc1ccc(Nc2ncc(CN3CCN(S(=O)(=O)N(C)C)CC3)cc2-c2nc(C)nc(N)n2)cn1 +Cc1c(CNC(=O)C2CNC(=O)N2C)cccc1C(F)(F)F +O=C(CCCCC[Se][Se]CCCCCC(=O)Nc1ccccc1)Nc1ccccc1 +Cc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cc(N3CCOCC3)ncc2[nH]1)C(F)(F)F +O=S(=O)(NCCNCCOCc1ccc(Cl)cc1)c1cccc2cnccc12 +CN1CCN(c2ccc(C(=O)Nc3cccc(CNc4ncnc5c(C(N)=O)cccc45)c3)cn2)CC1 +O=C(NO)c1ccc(CNC(=O)c2ccc(-c3ccccc3)cc2)cc1 +COc1ccc(-c2nnc(C34CCC(c5nc(-c6ccc(F)cc6)no5)(CC3)CC4)n2C)c(Cl)c1 +CSCC1OC(n2cnc3c(NCc4cccc(I)c4)ncnc32)C(O)C1O +COc1ccc2c(c1)CC(C(=O)Nc1c(F)cc(-c3cn[nH]c3)cc1OCCN(C)C)NC2 +C=CC1OC(n2cc(I)c3c(N)ncnc32)C(O)C1O 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+CC(=O)C=Cc1cc(C)c(Oc2cc(Nc3ccc(C#N)cc3)c(N)cc2[N+](=O)[O-])c(C)c1 +CCOC(=O)C=CC(CCC(N)=O)NC(=O)C(CC(=O)C(NC(=O)SC1CCCC1)C(C)C)Cc1ccc(F)cc1 +COc1cccc(CNCCCNc2ccnc3cc(Cc4ccc(F)cc4)ccc23)c1O +CCc1ccc(-c2nc3c(=O)[nH]c(=O)nc-3n(C)n2)cc1 +Cc1ccccc1CNc1nc(Cl)nc2c1ncn2C1OC(C(=O)N(C)C)C(O)C1O +O=C1NCC(c2ccc(F)cc2)C12CCN(C1(c3cccc(F)c3)CCCCC1)CC2 +O=C(NC1(CO)CCCCC1)c1cc(OCC(F)(F)F)c(C2CC2)cn1 +COc1cc(NC(=O)c2ccccc2)ccc1-c1cnco1 +Cc1ccc(OP(=O)(Nc2ccccn2)Oc2ccc(C)cc2)cc1 +CN1CCN(C(=O)c2cc3c([N+](=O)[O-])cccc3[nH]2)CC1 +COc1ccc(NCCNC(=O)C(Cc2ccc(-c3ccccc3)cc2)NC(=O)c2cccc(C)c2)cc1 +O=C1c2ccc(C#Cc3cccs3)nc2CCN1C1CCCC1 +CN1CCC2(C)C(=CC1=O)CCC1C3=CC=C(c4cccnc4)C3(C)CCC12 +NS(=O)(=O)c1nc2ccc(NC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)cc2s1 +CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N2CCCCC2CO)cc1-c1ccccc1Cl +Cc1cc(NC(=O)c2cccc(CN3CCOCC3)c2)nn1Cc1cc(Cl)ccc1OCC(C)C +O=C(O)COc1cccc(-c2ccc3c(c2)CC(NCC(O)c2cccc(Cl)c2)CC3)c1 +CC1(C)CC(CCN(Cc2ccccc2)C(=O)c2ccco2)(c2ccccc2)CCO1 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+C=C(c1ccccc1)c1ccc(C2CC3CCC(C2C(=O)OC)N3C)cc1 +O=C(O)Cc1ccccc1S(=O)(=O)c1ccc(-c2ccc(NC(=O)CF)cc2)cc1 +Cc1cc(OCF)cnc1C(=O)Nc1ccc(F)c(C2(C)COC(C)(C(F)(F)F)C(N)=N2)n1 +CC(C)Nc1ncc(-c2ccnc(-c3ccccc3Cl)n2)s1 +N=C(N)NCCCC1CC(C(=O)NCC(NC(=O)OCc2ccccc2)C(=O)O)=NO1 +NS(=O)(=O)c1ccc(N2N=C(C(F)(F)F)CC2c2cccc3ccccc23)cc1 +Clc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)c(-c3ccncc3)[nH]2)cc1 +COc1cnc2[nH]cc(Cc3ccc(NCc4ccccc4Cl)nc3F)c2c1 +O=C1NC(C(=O)O)Cn2cc(nn2)CC=CCOc2ccc(Cl)c1c2 +Cc1ncc(-c2ccnc(Nc3ccc(C(=O)NC4CCN(C)CC4)c(F)c3)n2)n1C(C)C +CCN1C(=O)N(c2cccc(C(=O)NC)c2)C(=O)N(c2ccccc2)c2cc(C(F)(F)F)ccc21 +N#Cc1ccc(OCc2ccc3nonc3c2)cc1OC(CCC(=O)O)c1ccccc1 +Cc1cc(CN2CCC(O)CC2)ccc1C(=O)Cn1ncc(OCc2ccc(Br)cn2)cc1=O +CN(C)Cc1cccc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)c1 +O=C(NCc1ccc(OC(F)(F)F)cc1)C1CCCC1C1=NOC(c2ccc(Cl)cc2)C1 +CCN1CC(C)(C)Oc2nc(N3CCOCC3C)nc(-c3ccc(NC(=O)Nc4cnc(N5CCOCC5)cn4)cc3)c2C1=O +CN(CP(=O)(O)O)C(Cc1ccc(-c2ccccc2)cc1)c1nnn[nH]1 +O=c1sc2ccccc2n1CCCCCN1CCN(C2CCCCC2)CC1 +O=C(Oc1ccc[n+]([O-])c1)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +O=C(Oc1ccc2c(c1)CCC2)N(Nc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CC(C)S(=O)(=O)NCC1CCC(NCCN2CCOc3ccc(F)cc32)CC1 +N#Cc1ncccc1CSc1nc(O)c(C#N)c2ccc(F)cc12 +CC(C)CC(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)OC(C)(C)C +CC(C)NC(=O)CCc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1 +CCCOc1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)ccc1OC +Cc1ccc2c(c1)nc(CCn1c(=O)c(C)nc3cccnc31)n2-c1ccccc1 +Cn1cncc1C(=O)NC1CCCC(Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1 +CC(C)C(NC(=O)c1cc(Cl)ccc1C(F)(F)F)C(=O)c1ccc([N+](=O)[O-])cc1 +COc1ccccc1N1CCN(CCNC(=O)Cc2ccsc2)CC1 +COC1CCC2(CC1)Cc1ccc(Sc3ccccc3)cc1C21NC(N)N(C)C1=O +COc1nc(NCCc2ccc(OCF)cc2)nc(-c2ccc(OC)c(C(C)(C)O)c2)n1 +O=C(O)c1cccc2c3c(n(Cc4ccccc4F)c12)CCCC3 +COc1ccc(C2=NN(CCCCc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)C3CC=CCC23)cc1Cl +CCN(CC(=O)NC(CC(=O)O)C(=O)NC(CCCC1CCCCC1)C(=O)O)C(=O)CCCC1CCNCC1 +C#CCCC(=O)Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)C(C)(C)CO3)cc1 +COC12CCC3(CC1CNC(=O)C(N)CO)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +NCc1cccc(-c2nc(-c3ccc(F)cc3)c(-c3ccnc4[nH]c(-c5ccccc5)cc34)[nH]2)c1 +Cc1ccc(-c2nc3ccc(C)cn3c2NCc2ccccc2)cc1 +O=C(O)c1ccc(CN(Cc2cccc(F)c2)S(=O)(=O)c2ccccc2)cc1 +Cc1cc(C(=O)Nc2cccc3c2CCCC3)nn1-c1cccc(C(F)(F)F)c1 +O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(O)CC1 +CN1CC2CCN(c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3)C2C1 +Cc1ccc2c(c1)c1c(n2CCc2cccnc2)CCN(C)C1 +Cc1cc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c(C)c(C)n1 +Cc1c(Nc2c(C#N)cncc2C=CCCN2CCN(S(C)(=O)=O)CC2)ccc2[nH]ccc12 +CC(=NNC(=O)COc1cccc2cccnc12)c1cccs1 +COc1cc(OC)cc(C(=C(C)C)c2ccc(OC)c(O)c2)c1 +CC1(C)COCCN1c1nnc(-c2ccc3[nH]cc(-c4cncc(C5CC5)n4)c3c2)o1 +COC(=O)Nc1ccc2c(c1)NC(=O)CCCCC(NC(=O)C=Cc1cc(Cl)ccc1-n1ccnn1)c1nc-2c[nH]1 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(Cc2ccc(C(F)(F)F)cc2)C(=O)CO)c1 +Cc1cc(C)cc(S(=O)(=O)N2CCc3ccc(C(=O)Nc4nc(CC(=O)O)cs4)cc32)c1 +CN(C)CCC(CNC(=O)Nc1ccc(F)cc1)c1ccc(-c2cccc(C#N)c2)cc1 +CC(C)C(C)(c1ccc(-c2cnc(N)nc2)nc1)c1noc(-c2cnn(CC#N)c2)n1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(-n2cc(Cl)c3cc(-c4ccc(F)cc4F)cnc32)cc1F +CC(C)CC(NC(=O)C1OC1C(=O)O)C(=O)Nc1c(F)cccc1F +CC(C)(CO)Nc1ccc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)nn1 +O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(c2cnc3n2CCCC3)CC1 +O=C(NC1CCCC1COc1ccccc1)C1CCN(c2nc3cc(Cl)ccc3o2)CC1 +COc1cccc2c1NC(=O)C(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)N=C2c1cccc(C)c1 +O=C(c1ccccn1)N(Cc1cccs1)C1(C(=O)NC2CCCCC2)CCCCC1 +CN(C)CCOc1ccc2c(c1)CCn1nc(-c3ccc(NC(=O)Nc4c(Cl)cccc4Cl)cc3)c(C(N)=O)c1N2 +O=C(Nc1ccc(OC2CN(C(=O)C3CCCC3)C2)cc1)N1Cc2ccncc2C1 +O=S(=O)(Nc1cccnn1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1C1=CCNCC1 +CC(C)c1ccc(C(=CCCCCC(=O)O)c2cccnc2)cc1 +CN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(F)cc2)n(C)c2ccccc12 +CC1(C)CC(NC(=O)Nc2ccc3c(c2)NC(=O)C(N2CCCOCC2)C3)c2ccc(F)cc2O1 +COc1ccc(-c2ccc3c(c2)NC(=O)C3=Cc2[nH]c(C)c(CCC(=O)O)c2C)cc1 +O=C(C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2)Nc1ncccc1F +Cc1nc(-c2nc(C(=O)NC(C(=O)OCC=CCCS)C(C)C)cs2)cs1 +Cn1c(=O)c2c(nc(N3CCCC(N)C3)n2Cc2ccccc2Cl)c2ccc(-c3ccccc3)cc21 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+O=C(O)c1ccc(-c2ccc(Cl)cc2)c(COc2ccc(-c3nc4cc(C(=O)O)ccc4n3C3CCCCC3)cc2)c1 +O=C1OCCN1c1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(C(O)C(F)F)cc2)c1 +CCCCCn1cc(C(=O)NC2C3(C)CCC(C3)C2(C)C)c(=O)c2cc(Br)ccc21 +CSCCC(NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CN1C(=NC(=O)OC(C)(C)C)NC(C)(c2cc(-c3cccc(-c4ncco4)c3)ccc2F)CS1(=O)=O +Oc1cc(-c2cccc(Cl)c2)nc2cc3c(cc12)OCO3 +CC(C)(C)c1cc(C(=O)Cn2c(=N)n(Cc3ccccc3)c3ccccc32)cc(C(C)(C)C)c1O +CC(C)c1cccc(C(C)C)c1OC(=O)NCC(NC(=O)OC(C)(C)C)c1ccccc1 +COCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccccc2)c1 +OCCN(CCO)CC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1 +Cc1ccc(N(C(=O)NCC2CCC(COCC(=O)O)CC2)c2ccccc2)cc1 +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)NN(C)C)c1 +CC1(CCC2CCCCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21 +CC1CCCN1c1cccc(Nc2cc(-c3ccc(OCCN4CCCCC4)cc3)nn3ccnc23)n1 +NC(=O)c1cccc2c1C(=O)N(c1cccc(C3CCNCC3)c1)C2 +Cc1ccc(NC(=O)C2CCCO2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +C=CC(O)C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 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+Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(=O)cc(N2CCOCC2)[nH]1 +COc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)oc3ccccc23)cc1Cl +NS(=O)(=O)c1ccc(CCNC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +CCN1c2ncc(CCOc3ccc4c(C(=O)O)cccc4c3)cc2C(=O)N(C)c2cccnc21 +CCC1CN(c2ncc(-c3nnc[nH]3)nc2C)C(C)CN1C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1ccc(Cn2nc(C(=O)NC3CC4CCC3(C)C4(C)C)c(C)c2-c2ccc(Cl)c(C)c2)cc1 +Nc1nc2c(N)[n+]3cnc2n1C1CC(O)C(COP(=O)(O)OP(=O)([O-])OCC2OC3C(O)C2O)O1 +COc1cc2c(N)nc(N3CCN(C(=O)CC4CCCN4)CC3c3ccccc3)nc2c(F)c1OC +CC1(C)CC(=O)c2c3c(n(-c4ccc(C(N)=O)c(NC5CCOC5)c4)c2C1)CCCC3 +Cn1nccc1CC(=O)NCc1cccc(C(F)(F)F)c1Cl +CC(C)Cn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)NC3=O +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(N3CCOC3=O)cc12)C(=O)O +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(N)CC2 +COC1C(c2ccc(C#N)c(Cl)c2C)=NN2CC(O)CC12 +CN1C2CCC1CC(CCOC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +Cc1ccc(C2=NN(c3nc(-c4ccc(Cl)cc4)cs3)C(c3ccc([N+](=O)[O-])cc3)C2)cc1C +O=C(Cn1c(=O)ccn(CCCCCOc2ccc(Br)cc2)c1=O)Nc1ccc(Cc2ccccc2)cc1 +O=C(NCc1ccc(F)c(F)c1)c1c(C2CCCC2)n(Cc2ccccc2)c2ccc(O)cc12 +CCN(c1ccc2nc(O)cc(C(F)(F)F)c2c1)C(C)C +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(C)cn3)CC2)CC1c1ccc(Cl)c(F)c1 +Cc1nc2c([N+](=O)[O-])c(Cl)c(Cl)cc2n1Cc1ccc(O)cc1 +Cc1ccc(C(=O)Nc2cccc(C(C)(C)C)c2)cc1-c1ccc(C(=O)NCC2CC2)cc1 +O=C(C1CCc2c(Cl)cc(OCc3ccc(C(F)(F)F)cc3)c(=O)n21)N1CCCC1 +CCN1C(=O)CNc2ncc(-c3ccc(-c4nc[nH]n4)nc3C)nc21 +O=S(=O)(Nc1nccnc1-c1ccc(Cn2c(-c3ccccn3)cc3ccccc32)cc1)c1ccccc1C(F)(F)F +CCOc1cc(Cl)ccc1-c1onc(C(=O)NC2CCOCC2)c1C +Cc1cc(NC(=O)c2ccccc2CO)nn1Cc1cc(Cl)ccc1OCC(C)C +O=C(NO)C1CC2(CC2)CNC1C(=O)N1CCC(c2ccccc2)C1 +COc1ccc(-c2c[n+](CC(=O)c3ccc(C)cc3)c3n2CCC3)cc1 +Nc1nc(NCCCCC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CCCCc1ccc(-c2n[nH]c3cnc(-c4cccnc4)cc23)nc1N1CCCC(N)C1 +O=C(N1CCC(c2c[nH]c3ncccc23)C1)C1(Oc2ccc(F)cc2)CC1 +O=C(Oc1cccc2c1C(=O)C=C(N1CC1)C2=O)c1ccc(F)cc1 +CCNC(=O)C1OC(n2cnc3c(NC45CC6CC(CC(C6)C4)C5)ncnc32)C(O)C1O +NC(=O)c1ccc2[nH]c(-c3ccc(C(O)c4ccc5c(c4)OCCO5)cc3)nc2c1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(NC4CCN(C)CC4)c3c2)cc(Cl)c1O +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCCC(F)(F)CC3)n2)cn1 +Cc1cc(N2CC3CCN(C(=O)c4cc(F)ccc4-n4nccn4)CC32)nc(N(C)C)n1 +CCCOc1ccc2c(c1)OC(c1ccc3c(c1)OCO3)C(C(=O)O)=C2c1ccc(OC)cc1 +CC(C)=CCc1c(O)cc(O)c2c1OC(c1ccc(O)cc1)CC2=O +O=C(COc1ccc(OCCCCSc2nc3ccccc3o2)cc1)COc1ccc(C(=O)O)cc1 +CCCCC(NC(=O)C(CC(=O)N1CCN(C)CC1)Cc1ccccc1)C(=O)NC(CC1CCCCC1)C(O)C(O)CC(C)C +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2cc(-c3ccccc3)ccc12 +O=S1(=O)Nc2c(cc(F)c(F)c2Nc2ccc(I)cc2F)OCC(O)C(O)CC12CC2 +Cc1ccc2ncccc2c1-c1cc(-c2c(C)noc2C)cc2[nH]c(C(O)CCO)nc12 +Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc1nccn12 +COc1ccc(-c2n[nH]c3c2C(C2CCCCC2)N(c2ccc4[nH]ccc4c2)C3=O)cc1 +CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1ccc(S(=O)(=O)Nc2nnc(C)s2)cc1 +Cc1nc2cnccc2n1Cc1ccc(C(=O)c2cn(C(=O)N(C)C)c3cccc(C(=O)OCc4ccccc4)c23)cc1 +Cn1cnc(S(=O)(=O)NCCOc2cccc(C(CN)Cc3ccccc3)c2)c1 +Cc1cc(COc2ccc(NC(=O)C3CCCCC34NC(=O)NC4=O)cc2)c2ccccc2n1 +CCN(CC)C(=O)c1ccc(C(=C2CCNCC2)c2cccc(C(F)(F)F)c2)cc1 +N=C(N)N1CCCC(NC(=O)CNC(=O)C(CCNC(=O)c2ccc3ccccc3n2)NS(=O)(=O)Cc2ccccc2)C1O +COc1c(-c2ccc(O)cc2)cc(O)c(-c2ccc(O)cc2)c1O +O=C(c1ccc(Cl)c(Cl)c1)N1CCC(CNCc2cccc(-c3cc[nH]n3)n2)CC1 +O=C(Nc1ccccc1)N1CCN(Cc2ccc(F)c(Br)c2)CC1 +Cc1ccc2c(NCc3ccc(NC(=O)C4CCN(Cc5c(F)cc(F)cc5F)CC4)cc3)nc(N(C)C)nc2c1 +CC1CCN(C(C(=O)Nc2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)CC1 +COc1nc(=O)ccn1C1OC(COP(=O)(O)OP(=O)(O)O)C(O)C1O +COCc1cc(OC)c(-c2csc3c(N(CC4CC4)C4CCOCC4)c(OC)nn23)c(OC)c1 +CC(OC(=O)Nc1conc1-c1ccc(CCC(C)(C)CC(=O)O)cc1)c1ccccc1Cl +CC(NC(CCc1ccc(O)cc1)C(=O)O)C(=O)N1CCCC1C(=O)O +Cc1ccccc1N1CCN(Cc2ccc(Cl)cc2)C(=O)C1=O +O=C(Nc1ccc(C2CCCNC2)cc1)c1ccc(C(F)(F)F)nc1 +N=C(N)NN=Cc1cc(Br)ccc1OCc1ccc(Cl)cc1 +Cc1[nH]cnc1CN1CCN(c2ccc(Cl)cc2)C1=O +CC1C=CC(=O)C(O)C(O)CC=Cc2cc(NCCO)cc(O)c2C(=O)OC1C +Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(c1)OCc1ccc(OCC(O)CO)cc1C2=O +O=C(c1ccc(F)cc1Cl)N1CCn2c(nnc2-c2cccc3cc[nH]c23)C1 +CCn1nc(-c2cccc(-c3cccc(C(N)=O)c3)c2)cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O +CC(C)N1CCN(C(=O)OC2CCN(c3ccc(C(=O)O)cn3)CC2)CC1 +CC(C)C(NCS(=O)(=O)c1ccc(N=Nc2ccccc2)cc1)C(=O)NC(C=O)Cc1ccccc1 +COc1ccc2c(c1)c(CC(=O)Oc1ccc(NC(C)=O)cc1)c(C)n2C(=O)c1ccc(Cl)cc1 +Cc1ccc2nccc(-c3sc(N)nc3-c3ccccn3)c2n1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)cc1C(=O)NCCCN1CCOCC1 +CN(C)C(=O)n1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(Cl)cc21 +O=C(CC12CC3CC(CC(C3)C1)C2)Nc1ccc(F)c(OCCCN2CCOCC2)c1 +CNc1nc(Nc2ccc(C(=O)N3CCC(N(C)C)CC3)cc2OC)ncc1C(F)(F)F +CC(C)c1ccc(NC(=O)N2CCNCC2COc2cccnc2)cc1 +Cc1cc(C2CCCN2C(=O)NCCc2ccc3c(c2)OCO3)nc(-n2ccnc2)n1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(F)cnc32)cc1NC1CCC(O)C1 +O=C(O)C1(N(CCn2ccnn2)S(=O)(=O)c2ccc(-c3ccc(Cl)cc3)cc2)CC1c1ccccc1 +CCN(CC)CCOC(=O)C(C)(COS(=O)(=O)c1ccc(C)cc1)c1ccccc1 +Cn1cnc2cc(-c3ccc(C(C)(C)O)nc3)nc(NCc3cnc[nH]3)c2c1=O +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCC(C(=O)O)C5)sc34)cc2F)c1 +CCOC(=O)N1CCC(c2ccc(Cl)cc2)C1C(=O)N1CCN(c2ccc(Cl)cc2C(N)C(C)C)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(-c4cccc(F)c4)nn3c2)c1F +CC1CN(c2c(C#N)c(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)CC(C)O1 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+O=C(OC1CCC(OC(=O)c2cc(O)c(O)c(O)c2)CC1)c1cc(O)c(O)c(O)c1 +CC(O)Cn1c2cnccc2c2cnc(Nc3ccc(N4CCNC(C)(C)C4)nn3)nc21 +CCNCC#CCCC(=O)C(O)(c1ccccc1)C1CCC1 +O=C1Nc2ccccc2Nc2cc(-c3ccncc3)ccc21 +CC(=O)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2cccc(F)c21 +CCCC(=O)NC1(C(=O)NCCCNCCCCNCCCN)CCc2ccccc2C1 +O=C1CC(O)CC(C=Cc2c(Cl)cc(Cl)cc2CCc2ccccc2)O1 +c1ccc(OCC2CN(Cc3ccc4ccccc4c3)CCO2)cc1 +CCOC(=O)COc1ccc(NC(=O)c2ccc(C(=N)N(C)C)cc2)c(C(=O)Nc2ccc(Cl)cn2)c1 +COc1ccc(CS(=O)(=O)C=Cc2c(OC)cc(OC)cc2OC)cc1 +Clc1ccc(Nc2nnc(-c3cc4ccccc4[nH]3)s2)cc1 +CC(=O)Nc1cc(Nc2cc(NC3CC3)n3nccc3n2)ccc1C +CCCNC1CCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)CC1CS(=O)(=O)c1ccccc1 +O=C(NN=Cc1ccccc1O)c1cccc(C(F)(F)F)c1 +CS(=O)(=O)NCCCCCN1C(=O)N(CCCCCNS(C)(=O)=O)C(Cc2ccccc2)C(O)C(O)C1Cc1ccccc1 +N#Cc1c[nH]c2c(C(=O)N3CCN(CCc4ccc(F)cc4)CC3)cccc12 +COc1cc(C=NN(C)C(=O)CSc2cc(C)nc3ccccc23)cc(OC)c1OC +CCN(C(=O)C1CCN(S(=O)(=O)c2ccc3cn[nH]c3c2)CC1)C(C)c1ccccc1 +CC12C=CC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(OC(=O)c1ccco1)C(=O)CSc1nccc2ccccc12 +CCN1CCN(c2nc(C)cc(N(CCCNc3ccnc4cc(Cl)ccc34)Cc3ccco3)n2)CC1 +O=C1Nc2ccccc2N(C(=O)CC2CCCN3CCCCC23)c2ncccc21 +N=C(N)NCCC(=O)Nc1cccc(SC(CC(=O)O)c2cccnc2)c1 +C=C(OC(C)=O)c1ccc2c(c1)COP(=O)(OCC1C=CC(n3cc(C)c(=O)[nH]c3=O)O1)O2 +CC(Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)Cc1cnc2nc(N)nc(O)c2n1 +Cc1c(O)nc(SCC(C)C)nc1Cc1c(F)cccc1F +c1cc2c3cnc(Nc4ccc(N5CCNCC5)cn4)cc3n(Cc3ccsc3)c2cn1 +CNC(=O)c1ccc(Nc2nc(OC3CCOC3)c3c(-c4ccc5nc(C)oc5c4)c[nH]c3n2)c(OC)c1 +CN(CC(=O)NC(CCCCN)C(=O)C(=O)Nc1ccc(Oc2cccnc2)cc1)C(=O)c1ccccc1Sc1ccccc1C#N +COc1ccc(-c2nc(COc3ccc4c(c3)CC(C(=O)O)O4)sc2-c2ccc(C(F)(F)F)cc2)cc1 +C#CCn1c(=O)c2c(-c3nc(C#N)cn3C)n(Cc3ccnc4ccc(Cl)cc34)nc2n(CC2CC2)c1=O +COc1ccccc1CN1C2C3C4CC5C6C4C2C6C1(O)C53 +CC(C#N)CNc1nccc(-c2nc(C3CC3)[nH]c2-c2cccc(NS(C)(=O)=O)c2Cl)n1 +Nc1ncnc2c1ncn2C1OC(COS(=O)(=O)NC(=O)C(N)Cc2c[nH]cn2)C(O)C1F +CCN(CC)c1ccc2nc3c4ccccc4c(=Nc4ccncc4)cc-3oc2c1 +COc1cc(Nc2ncc3c(C)nc(-c4ccccc4)n3n2)cc(OC)c1OC +O=S(=O)(Nc1cscn1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1Br +COc1cc(Sc2c(-c3nccs3)[nH]c3ccccc23)cc(OC)c1OC +N=C(NCCCc1c[nH]cn1)NCCCC(c1ccc(F)cc1)c1ccccn1 +COc1cc(C=C(C#N)c2nc3ccccc3[nH]2)ccc1OCc1ccccc1Cl +COc1cc(C)c(S(=O)(=O)NC(=O)c2cccc3cccnc23)cc1-c1ccc(C#CCO)s1 +CC(C)C(=O)Nc1cccc(C2CCN(Cc3ccc(Oc4ccc(Cl)cc4)cc3)CC2)c1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3ccnc(Oc4ccccc4)c3)c(C(=O)O)n1)CC2 +CC1(C)CNc2c(cccc2S(=O)(=O)NC(CCCN=C(N)N)C(=O)N2CCC(CCF)CC2)C1 +Cn1cc(-c2cccc(N3CCc4c(sc5c4CCCC5)C3=O)c2CO)cc(Nc2ccncn2)c1=O +Cn1c(=O)c2[nH]c(C34CC5CC(CC3C5)C4)nc2n(C)c1=O +CCSc1nnc(Cc2ccc(Cl)cc2Oc2ccccc2F)[nH]1 +CN(C)Cc1ccc2c(c1)CN(C(=O)Nc1ccc(-c3c[nH]c(=O)c4ccccc34)cc1)C2 +COC(=O)c1sc2ncnc(Nc3cccnc3OCC3CC3(F)F)c2c1C +COc1ccc(CN2C(=O)C(=O)c3cc(S(=O)(=O)N4CCCC4COc4ccccc4)ccc32)cc1 +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCc2ccc(CNC(=O)c3ccccc3)cc2)C1 +COc1cccc(CCCCCCCCc2cccc(OC)[n+]2C)[n+]1C +O=C(CC=Cc1ccccc1)Nc1nc2ccccc2c(=O)s1 +N#Cc1ccc(-c2ccc(C(=O)N(Cc3ccccc3-c3ccccc3F)c3ccc(N4CCNCC4)cc3)o2)cc1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(C)(C(F)(F)F)Oc4ccccc43)cc21 +COc1cnc(C(=O)Nc2ccc(Cl)c(C3(C(F)F)N=C(N)OC4CC43)c2)c(C)c1 +Cc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1Cl +CC(C)N1CCN(C(=O)OC2CCN(c3ccc(=O)[nH]n3)CC2)CC1 +CN(C)CCOc1ccc(C(=C(CCCO)c2ccccc2)c2ccc(Cl)cc2)cc1 +Nc1ncc(-c2cc(N3CC4CCOC4C3)nc(N3CCC3)n2)cc1OC(F)F +CCNC(=O)CC1N=C(c2ccc(Cl)cc2)c2cc(OC)ccc2-n2c(C)nnc21 +Cn1ncnc1C1c2n[nH]c(=O)c3cccc(c23)NC1c1ccc(F)cc1 +O=C(NC(Cc1ccc(-c2ccc3ccccc3c2)cc1)C(=O)O)C(CS)Cc1ccccc1 +c1ccc(-c2cc(CN3CCCNCCNCCCNCC3)cc(CN3CCCNCCNCCCNCC3)c2)cc1 +CCC(C)c1cccc2c1OP(=O)(OCC1C=CC(n3cc(C)c(=O)[nH]c3=O)O1)OC2 +COC(=O)N(CC(=O)O)Cc1cccc(OCc2nc(-c3ccc(Cl)cc3)oc2C)c1 +CCCCCC(=O)c1ccc(OCCCN2CCN(S(=O)(=O)C(C)C)CC2)cc1 +Cc1c(N2C(=O)C(C)(C)N(CCCS(N)(=O)=O)C2=S)ccc(C#N)c1C(F)(F)F +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4cccc(-n5cccn5)c4)nc23)N1 +CC(C)CN(Cc1ccc2c(c1)C=CC(C)(C)O2)S(=O)(=O)c1cc(Cl)ccc1Cl +CCCCOc1ccc(S(=O)(=O)N2CC(=NN3CCNCC3)CC2C(=O)NO)cc1 +N#Cc1cccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 +CC(C)N1CCN(C(CN2CCN(CCc3ccccc3-c3ccccc3)CC2)c2ccc(F)cc2)CC1 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+COc1cc2c(cc1OC)C(=O)C(=Cc1ccc(CN(C)C)cc1)C2 +CCCOc1[nH]cc2nc3ccc(OCc4ccccc4)cc3c-2c1COC +O=S(=O)(c1cccc2ccccc12)c1n[nH]c2ccc(NCC3CCNCC3)cc12 +CC(C)Oc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +CC(C)(C)C(O)C(=O)N1CC2CC2C1C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +Cn1cc(-c2ccc(-c3cnc(N)c4ccc(C(=O)N5CC(F)(F)C5)nc34)cc2)cn1 +CNC(C)C(=O)NC1CCc2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O +Cc1c(C(O)CN2CCCC3(CCN(CC(O)c4ccc5c(c4C)COC5=O)C3)C2)ccc2c1COC2=O +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1cccnc1O +COc1cc(C(O)CN2CCN(CCc3ccc4c(c3)COC4=O)CC2)c(F)cc1C#N +N#Cc1ccnc(Nc2cc(C3CCN(C4COC4)C3)n(C3CCCC3)n2)c1 +Cc1cncc(-n2nnc3c2CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)C3C)n1 +COC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5 +CCCN(CC)Cc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1 +O=C(CCC(NC(=O)OCc1ccccc1)C(=O)OCc1ccccc1)NNc1ccc(OCc2ccccc2)cc1 +COC1COCC1NC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1 +CCOc1ccccc1CNc1nc(Cl)nc2c1ncn2C1C(O)C(O)C2CC21 +CCc1cccc(N(C)C(=N)N(C)c2cc(Br)ccc2Br)c1 +Cc1nc2ccc(-n3ncc(C(=O)c4[nH]c5ccccc5c4F)c3N)cc2[nH]1 +NC1CCCN(c2ccncc2Nc2ncc3ccc(-c4cc(C(=O)NC5CC5)ccc4F)nn23)C1 +Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(F)c2)c2c(N)ncnc21 +O=C(Cc1ccc(-n2cnnn2)cc1)N1CCN(CCc2ccc3nonc3c2)CC1 +CCCc1nc(-c2cccnc2)cn2c(CC(=O)NC(CC3CCCCC3)C(O)C3CCCCC3)nnc12 +Cc1cc(C)c(CNC(=O)c2cc(-c3cnn(C)c3)cc(N(C)C3CCC(N)CC3)c2C)c(=O)[nH]1 +CCCCN1CCC(CNC(=O)c2cccc3c2OCCO3)CC1 +CNc1nc2c(N(C)C)ncnc2n1Cc1cccc(NC=O)c1 +COCCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(C)c4)nc2)CC3)n1 +c1cc(C[n+]2ccc(N3CCCCC3)cc2)cc(-c2cccc(C[n+]3ccc(N4CCCCC4)cc3)c2)c1 +CC(C)(C)OC(=O)N1CCN(c2ncc(OCc3ccc(S(C)(=O)=O)cc3)nn2)CC1 +c1ccc(CCN2C3CCC2c2c([nH]c4ccccc24)C3)cc1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C(F)(F)F)nn3)c2)c2cnc(N)nc21 +O=C(NCCN1CCC2(CC1)C(=O)NCN2c1ccc(Cl)cc1)c1ccc2ccccc2c1 +CN(C)CCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccon2)cc1 +Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCCCn2ccnc2)cc1Cl +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(C#N)c2OCC2CCCC2)nc1 +O=C(C(=Cc1ccccc1)n1cncn1)c1ccc(Cl)cc1Cl +NC(=O)C1(c2ccccc2CCc2nc(Nc3cn[nH]c3)ncc2Cl)CC1 +CCCCCCCCc1ccc(OCC(=O)COc2ccc3c(c2)cc(C(=O)O)n3CCCCCC(=O)O)cc1 +O=C(Nc1ccc(F)c(-c2nc3cc(-c4cncc(Cl)c4)cnc3[nH]2)c1)N1CCCC1 +CNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(C4CCC(OC)CC4)c3n2)cc1 +CC(C)(C)n1nnc2c1CCC(n1cnc(-c3ccc(F)cc3)n1)C2 +O=C1CC(CNc2ncc(C(=O)NC3C4CC5CC3CC(O)(C5)C4)c(C3CCCC3)n2)CN1 +CS(=O)(=O)C1CCC(NC(=O)c2cnc(-n3ccc4cc(C#N)cnc43)cc2NC2CCOCC2)CC1 +CC(N=Nc1nc2ccccc2o1)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 +CN1CC(C(=O)N2CCN(c3ccccn3)CC2)CC2c3cccc4[nH]c(Cl)c(c34)CC21 +COc1cc(C)c(Nc2nc(C)nn(C(C)C3CC3)c2=O)c(C)c1 +C=Cc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C(Nc1cn(CCNCc2ncco2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +COCC(=O)NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(C2(CNC(=O)Cc3ccccc3)CCCCC2)CC1 +CC1CCCCN1C(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 +CC(C)(O)CCNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +NC(=O)c1cc(-c2ccccc2)nc2c1cnn2Cc1ccncc1 +Fc1cccc(COc2ccc(Nc3ncnc4ccc(-c5ccc(N6CCOCC6)cc5)cc34)cc2Cl)c1 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+CCCc1c(OCCCCCCc2cccc(OCCCCCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O +NC(=O)CC(N)C(=O)NS(=O)(=O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1O +CN1CCC(c2c[nH]c3ccc(NS(=O)(=O)c4cccc5ccccc45)cc23)CC1 +O=C(c1ccc(Oc2ccccc2)cc1)c1cc2c(Cl)c(O)ccc2[nH]1 +O=C(c1ccc(SCc2ccccc2B(O)O)nc1)N(Cc1ccncc1)c1ccc(F)cc1 +Cc1onc(C(=O)N2CCC(Nc3cc(=O)n(C)c4cc(F)c(F)cc34)CC2)c1C +OCc1cnn2cc(-c3c(F)cccc3F)c(-c3ccc(CN4CC(c5n[nH]c(-c6ccccn6)n5)C4)cc3)nc12 +COc1ccc(-c2cc(-c3cccc(NS(C)(=O)=O)c3)nc(N)c2C#N)cc1 +CCCCCC(=O)Nc1ccc2c(c1)C(C)(c1ccccc1)CC(C)(C)N2C(C)=O +Cc1nsc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)n1 +O=C(O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCOc1ccccc1-3 +O=C(NC1CCCC1Nc1ncc(C(F)(F)F)cc1F)c1cc(F)ccc1-c1ncccn1 +Cc1cc(C)n2nc(-c3ccc(S(C)(=O)=O)cc3)c(-c3ccc(F)cc3)c2n1 +CCC1CN2CCc3cc(O)c(OC)cc3C2CC1CC1(O)NCCc2cc(O)c(OC)cc21 +COc1cc(Nc2nc3cc(N)cc(N)c3nc2-c2ccccc2)cc(OC)c1 +Nc1ncnc2scc(C(=O)Nc3ccc(NC(=O)Nc4ccccc4)cc3)c12 +COc1ccc(-c2ccn(CCC(C)(C(=O)NO)S(C)(=O)=O)c(=O)c2)cc1 +CNC(=O)c1nc(C2CC2)ccc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +O=C(NC1CCCCCC1)C(=O)N1CCN(C(c2ccc(Cl)cc2)c2ccccc2Cl)CC1 +O=C(Nc1ccc(CC2CCC(C(O)c3cccnc3)N2)cc1)C1CCc2sc(-c3ccc(F)cc3)nc21 +Cc1nc(NCCC(F)(F)F)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +N#Cc1c(-c2ccc(-c3cccnc3)cc2)nc2ccncc2c1O +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5ccncc5)no4)cc3)cc2)C(=O)NC(=O)NC1=O +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccco2)c1 +CC1(C)CC(Nc2ncnc(NC3CC(O)C(COS(N)(=O)=O)C3)c2F)c2ccccc21 +NS(=O)(=O)c1ccc(C(=O)NNC(=O)Nc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)cc1 +Oc1nc(Oc2cnn(CCN3CCOCC3)c2)nc2cnccc12 +CCc1ccc(S(=O)(=O)NC2c3cc(NC(=O)C4CCCN4Cc4cccc(OC)c4)ccc3CCC2O)cc1 +CCOC(=O)c1cc(F)cc(Nc2cc(NCC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +Cc1oc(S(=O)(=O)Nc2ccccc2)cc1NC(=O)Nc1ccccc1 +CNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4cccc(Cl)c4)ccc3C)CC2)ncn1 +O=C(O)c1cccc(Oc2ccc(CN3CCC(N4C(=O)N(C5CCCCC5)CC4c4ccccc4)CC3)cc2)c1 +O=C(c1nc(-c2c[nH]c3cc(Cl)ccc23)c[nH]1)c1c[nH]c2cc(Cl)ccc12 +CCc1nc2c(-c3ccc(OC)nc3C)ccnc2n1C(C)C1CCC1 +CCOc1ccc(-c2cn3c([n+]2Cc2ccccc2)SCCC3)cc1 +O=C(NC(c1ccc(OC(F)(F)F)c(F)c1)C1CNCCO1)c1ccc2cnc(NC3CCOCC3)nc2c1 +COc1cc2c(Nc3ccc(Cc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1OCCCN1CCOCC1 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CCC(F)(F)C1)CC2 +O=S(=O)(Nc1ccc(CCNCC(O)c2ccccc2)cc1)c1ccc(Cc2nc(CCc3ccccc3)cs2)cc1 +CN(C1CCC(C(N)Cc2cc(F)ccc2F)CC1)S(=O)(=O)c1cccc(C(N)=O)c1 +Cc1cn(C2CC(OCP(=O)(NC(C)C(=O)OC(C)C)Oc3ccccc3)CO2)c(=O)[nH]c1=O +CCOC(=O)CN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(C)(C)C +CN(C(=O)Cc1ccccc1Cl)C1CCCCC1N1CCCC1 +CC1Cc2cc(F)ccc2N1C(=O)Cc1nc(N2CCOCC2)c(F)c(=O)[nH]1 +NC(=O)c1cccnc1COc1cc(-c2ccc3c(c2)CCNC3=O)cc2ncccc12 +CC(C)CC(NC(=O)Cc1ccc2c(c1)OCO2)C(=O)NC1CCN(Cc2ccc(OCCCN(C)C)cc2)C1 +Cc1cc(-n2[nH]c3c(cnc4cc(Cl)ccc43)c2=O)cs1 +COC(=O)c1ccc(NC(=O)CN2CCC(Nc3cc(Oc4c(C)cc(C)cc4C)n4ncnc4n3)CC2)c(Cl)c1 +COc1cccc2[nH]cc(CN3CCC(n4c(=O)[nH]c5ccccc54)CC3)c12 +COc1cc(-c2cc(NC(=O)Nc3cc(OCCN4CCOCC4)ccc3C)cc(OC)c2OC)ccc1C(C)=O +CC(C)CNC(=O)c1ccc(-c2ccc(C#CCO)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +CNC(=O)C(NC(=O)C(CCc1ccccc1)CP(=O)(O)Cc1ccc(Cc2cccc(F)c2)cc1)C(C)(C)C +CCN1C(C)CN(c2cc3c(cc2OC)CCN3C(=O)c2ccc(-c3cccc(C)n3)c3ccccc23)CC1C +Cc1cc(CNC(CO)C(=O)O)c(OCc2cccc(C#N)c2)cc1OCc1cccc(-c2ccc3c(c2)OCCO3)c1C +CNc1nc(NCCCN(C)C)c2sc(-c3ccc(N4CCNCC4)cc3)cc2n1 +O=C(O)c1cc(C(F)(F)F)ccc1N1CCC(OCC2CC2)C1 +CC(=O)NCC(=O)N1CCC2(CC1)CCN(Cc1cccc(C(F)(F)F)c1)c1ccccc1O2 +O=c1c2cnc3cccc(O)c3c2[nH]n1-c1ccccc1 +CC(=O)NC12CC3CC(C1)C(OC(=O)N1CCC(NC(=O)OC(C)(C)C)C1)C(C3)C2 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1c(Cl)cccc1Cl +CC(C)=CCCC(C)=CCCCCCCC(P(C)(=O)O)P(=O)(O)O +Cc1csc(-c2nc(N)nc3c2nnn3Cc2ccccc2F)n1 +CCCC1(CC(=O)O)OCCc2c1[nH]c1c(C)c(OCc3cnccn3)cc(C#N)c21 +Cc1ccccc1OC(CCN1CCC(n2c(O)nc3ccccc32)CC1)C(C)C +O=C1NCC2=C1C(c1ccc(F)c(Br)c1)C1=C(O)CCCC1=N2 +CC1CCC2C(CSc3ccccc3)C(=O)OC3OC4(C)CCC1C32OO4 +O=C(NCCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 +COc1cc(N)c(Cl)cc1C(=O)NCC1CC[N+]2(C)CCCC12 +CC(c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-c3c(C(=O)N(C)C)sc4c(C)ccc(C)c34)cc2)cc1 +CC(O)(CC(=O)OC(C)(C)C)CC(O)CSc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)[nH]1 +O=C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)Nc1ccc(Cc2nnn[nH]2)cc1 +CC(C)c1ccc(S(=O)(=O)c2n[nH]c3ccc(NC4CCNCC4)cc23)cc1 +Cc1cccc(C)c1NC(=O)c1ccc(-c2ccccc2)o1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1ccc(F)cc1F)Oc1ccccc1-3 +COc1ccc(Cn2c(N3CCNCC3)nc3ccccc32)cc1 +CCOc1ccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(CCN3CCOCC3)C2=O)cc1 +CCS(=O)(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(S(C)(=O)=O)cc2)[nH]1 +O=C(C=Cc1c(C(=O)O)[nH]c2c(Cl)cccc12)Nc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 +O=S(=O)(c1ccc(CNCCc2ccc(Cl)cc2Cl)cc1)N(Cc1c[nH]cn1)CC1CCCCC1 +N#Cc1nc(NCc2ccc(Cl)c(Cl)c2)c2ncn(Cc3ccccc3)c2n1 +COc1ccc(-c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)cc1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(C#CCO)ccn23)c1 +Cc1cc(C)cc(Sc2c(Cn3cnc(C)n3)c(C)[nH]c(=O)c2I)c1 +CCc1ccccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O +O=C(Cc1c(Cl)ccc(NCC(F)(F)c2ccccn2)[n+]1[O-])NCc1ncccc1F 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+O=C(NC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)C(S)Cc1ccccc1 +Nc1ccc(-c2cccc(F)c2)cc1NC(=O)c1ccc(CNc2ccncc2)cc1 +Cc1ccc(CN2CCCC(COc3ccc(-c4nc5cc(C(N)=O)ccc5[nH]4)cc3)C2)cc1 +Fc1cc(-c2nc(N3CCN(c4ncccc4C(F)(F)F)CC3)[nH]c2-c2cc(F)c(F)c(F)c2)cc(F)c1F +O=C(O)CCC=CCC1COC(c2cccs2)OC1c1cccnc1 +Cc1ccc(NC(=O)C2CCN(C)CC2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COc1ccc(C(=O)C=Cc2ccc(C(=O)OC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)cc1OC +Nc1ncnc2c(CN3CC(O)C(CSCc4ccccc4)C3)c[nH]c12 +C=CCCCN(C)C1CCC2(C)C(C(C)CCCC(C)C)CCC2(C)C1O +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C(F)F +Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2cc(F)c(F)c(F)c2)c2cc[nH]c2c1=O +Cc1ccc(CN2CCC(F)(F)C(CCc3ccccc3)C2)cc1C +Cn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2-c2ccc(F)nc2)CC1 +C=CCNc1nc(N2CCC(NCC3c4ccccc4N(CCC)S(=O)(=O)c4ccccc43)CC2)nc2c1ncn2CC=C +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cccc(Cl)c3F)ccc2[nH]1 +O=C(C1CCCN(c2ccc3nc(-c4ccnc(C5CC5)n4)[nH]c3n2)C1)N1CCC(F)C1 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+NS(=O)(=O)c1ccc(N2C(=O)c3cccnc3C2=O)c(I)c1 +CN(C)CCC1=C(C(c2ccccc2)c2ccccn2)c2ccccc2C1 +Cc1cc2c(-c3cn[nH]c3)cnc(NC3CCNCC3)c2[nH]c1=O +O=C(C1CNCCC1(O)c1ccc(F)c(F)c1)N(Cc1cn(Cc2cccc(F)c2)c2cccc(F)c12)C1CC1 +Cc1ccc(-c2ncoc2SCC(=O)Nc2ccc(-c3ccc(CC(=O)O)cc3)cc2Cl)c(Cl)c1 +CC12CCC3C(CCC4CC5(CCC43C)CNC(Cc3ccccc3)C(=O)O5)C1CCC2=O +O=C1N(Cc2cncn2Cc2ccccc2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +O=C(Nc1cccc(O)c1)c1ccc(OCCCN2CCCC2)cc1OCc1cccc(F)c1 +CS(=O)(=O)n1cc2c(n1)CN(C1CSC(c3cc(F)cc(F)c3F)C(N)C1)C2 +C=CS(=O)(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +CCCCNC1=NC(=O)C(=Cc2ccc3ncccc3c2)S1 +C=CCn1cc(C(N)=O)c(Nc2ccc(I)cc2F)cc1=O +CC1(C)Cc2c(c(N3CCOCC3)nc3oc4c(NCc5cccnc5)ncnc4c23)CO1 +NC(Cc1ccc(O)cc1)C(=O)N1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 +Cc1ccccc1NC(=O)c1cc(C)n(-c2cccc(C(F)(F)F)c2)n1 +COc1cc(Sc2c[nH]c3ccc(Cl)cc23)cc(OC)c1OC +CCN(C(=O)CNC(=O)CN)C1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cccnc3NCCN(C)C)NC(=O)NC1=O)C2 +CC(=O)c1ccc(SCc2cc3c(cc2O)CCCO3)cc1 +COc1cccc(CNCC2(N3CCN(C(=O)C4CN(C(C)C)CC4c4ccc(Cl)cc4)CC3)CCCCC2)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1ccc(C(=O)NC2CCCC2)c(Cl)c1 +O=C(O)c1cccc(Cn2c(-c3ccoc3)c(C3CCCCC3)c3ccc(C(=O)O)cc32)c1 +Cc1ncc(C)n2nc(CCc3nc(N(C)C4CC4)nn3C)nc12 +O=C(Nc1ccccc1)N(Cc1cc(Br)ccc1O)c1ccccc1Cl +C#CCCOC(=O)N1CCc2c(F)ccc(-c3cc(CC(=O)O)ccc3OCC)c2C1 +CN(CCN1CCCCC1)C(=O)N1CCC(Cc2ccccc2)CC1 +Cc1cccc2c1CCN(C(=O)C1CCCCC1C(=O)O)C2CN1Cc2ccccc2C1=O +N=C(N)NCCCC1NC(=O)C(C(O)(c2c[nH]c3cc(Br)ccc23)c2c(Br)ccc3c(=O)o[nH]c23)NC1=O +COc1ccc(CN2CCC(C(=O)N(Cc3cc(Cl)c4c(c3)OCCCO4)CC(C)C)C2)cc1[N+](=O)[O-] +O=C(Nc1ccc2[nH]c(C=CC(=O)N3CC(CCl)c4c3cc(O)c3ccccc43)cc2c1)c1cc2ccccc2[nH]1 +CCc1ccc(NC(=O)c2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1 +CC1C(Nc2ncc(Cl)cn2)CCCN1C(=O)c1ccccc1-n1nccn1 +Cn1c(-c2cccc(Cl)c2)csc1=NC(=O)c1ccccc1 +C=CC(=O)NCCCCC(NC(=O)OCc1ccccc1)C(=O)O +CCCn1cc(-c2cc(OCc3ncccc3C(N)=O)c3cccnc3c2)cn1 +NP(=O)(OCCCCCOc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)N(CCCl)CCCl +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NC3CCCC3O)c12 +CN(CCOc1ccc(CC(Nc2ccccc2C(=O)C2CCCCCC2)C(=O)O)cc1)c1nc2ccccc2o1 +CCOc1cc(-c2cnn(CCC(=O)O)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +Nc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2)nn1-c1ccccn1 +CC(C)c1noc(N2CCC(COC3CCC(c4ccc(S(C)(=O)=O)cc4F)CC3)CC2)n1 +COc1cccc(-c2c(C)n(Cc3ccccc3F)c3nc(C(C)(C)C)c(CN(C)Cc4ccccn4)n3c2=O)c1 +COc1cc(C#CC2CCCC2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3cccnn3)ccc21 +COc1cc(NC(=O)Cc2nc(N3CCOCC3)cc(=O)n2C)ccc1F +O=C1Nc2cc([N+](=O)[O-])ccc2C1=C1Nc2ccccc2C1=NO +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1CCCC(=O)NCCOCCO +COc1ccc(C2Sc3ccccc3-n3c(CNCCc4ccc(OC)c(OC)c4)ccc32)cc1 +CCCc1c[nH]c2c(F)cc3c(c12)CC(N(CCC)CCC)CC3 +CCCN(CCc1ccc(OC)cc1)C1Cc2cc(OC)c(OC)cc2C1 +N#Cc1cccc(C(=O)NCCCCCC(=O)Nc2ccccc2N)c1 +CCN(CC)CCCCn1c(N)c(-c2nc3ccccc3[nH]2)c2nc(C#N)c(C#N)nc21 +CCc1noc(-c2ncn3c2CN=C(c2ccccc2)c2c(Cl)cccc2-3)n1 +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1cccc(Oc2ccccc2)c1 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCCCN4CCCCC4)cc3)oc2c1 +CCOc1n[nH]c2cc(NC(=O)NC(CS(C)(=O)=O)c3ccccc3)ncc12 +COc1cc(=O)oc2cc(OCCCCCN3CCN(CC(=O)Nc4c5c(nc6ccccc46)CCCC5)CC3)ccc12 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCCCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 +O=C(C=Cc1ccccc1OCc1ccc2ccccc2c1)NS(=O)(=O)c1cccs1 +CN1CCN(CC(=O)N2CCc3nc(-c4cc5cc(Cl)ccc5[nH]c4=O)[nH]c3C2)CC1 +COc1ccc2[nH]cc(C3CCN(CCCCN4C(=O)CC(c5c[nH]c6ccccc56)C4=O)CC3)c2c1 +c1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOC4)N3)n2)cc1 +O=C(OC1CCC(c2ccc(-c3nc4[nH]c(OC5COC6C(O)COC56)nc4cc3Cl)cc2)CC1)N1CCOCC1 +CC1(C)CCc2c([nH]c3ccc(Cl)cc3c2=O)C1 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2ccc(N3CCOCC3)cc2)cc1 +CCOC(=O)c1cnc(NCc2ccc(C)cc2)n2nc(-c3ccco3)nc12 +O=C(N1CCN(Cc2ccc(-c3ccccc3)cc2)CC1)n1cccn1 +COc1ccc(N(C(=O)c2occc2C)C(C(=O)NCC(C)O)c2ccccc2F)c(OC)c1 +O=[N+]([O-])c1cc(N=Nc2ccc3ccccc3c2)ccc1O +COc1c(CC=C(C)C)c(O)c(C(=O)O)c(CCc2ccccc2)c1CC=C(C)C +COc1ccc(N2CCN(Cc3nc(N)nc(Nc4ccc(C)c(Cl)c4)n3)CC2)cc1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2c(C(=O)O)cccc12 +CNc1nc(NCc2ccc(NC(=O)c3ccc(F)cc3Cl)cc2)c2cc(C)ccc2n1 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+O=C(Nc1nc2c(s1)CN(CCO)CC2)N1CCC(N2CCc3ccc(F)cc32)CC1 +CCCCN(CCCC)CCCOc1ccc(S(=O)(=O)c2c(C)cn3ccccc23)cc1 +Cc1n[nH]c(Nc2ccc(OC(F)(F)F)cc2)c1C#N +O=C(Nc1ccc(O)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O +O=C(c1ccc(Oc2ccc(Cl)cc2)cn1)N1CCCN(C2CCC2)CC1 +CC1=CC2SC(=C1)C=C(C)CCC=C(C)CCC2C(C)C +NC(=O)c1cc([N+](=O)[O-])ccc1COP(N)(=O)N(CCCl)CCCl +COc1ccccc1-c1ccc2c(c1)C(C(C)OCCC1CCCCC1)=CC(C)(C)N2 +Cn1c(-c2cn(CC3OC(O)C(O)C(O)C3O)nn2)nc(-c2ccc(F)cc2)c1-c1ccncc1 +CCCn1c(=O)c2nc(-c3ccccc3)[nH]c2n(C)c1=O +OC12CC3CC(C1)CC(Nc1ncnc4c1nn1ccccc41)(C3)C2 +CC(C)(C)OC(=O)NCC(=O)Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1 +O=C(Nc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +CC(C)C(NC(=O)C1CCCN1C(=O)C(N)C1CCCCC1)C(=O)N1CCCC1B(O)O +COc1c(I)cc(I)cc1C(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1(C)CCN(C)C1)CC2 +O=C1C2C3C=CC(C3)C2C(=O)N1CCCCN1CCN(c2ncccn2)CC1 +CC1CN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2F)CC(C)C1(O)c1c(F)cccc1F +CCOCn1c(Cc2ccccc2)c(N(C)C)c(=O)[nH]c1=O 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+O=C(Nc1ccccc1)N1CCC(Nc2cc[nH]c(=O)c2-c2nc3ccccc3[nH]2)CC1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)nc2ccc(-c3cccc(CN(C)C)c3)cc2c1=O +COc1ccc(C=C2SC(c3ccccc3Cl)=NC2=O)cc1 +O=C(Nc1nc(-c2ccncc2)cs1)NC(c1ccccc1)c1ccccc1 +Nn1c(SCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2cc([N+](=O)[O-])ccc2c1=O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)OCc4ccccc4)nc23)N1 +O=C(NC(Cc1cccnc1)C(=O)NC1C(=O)N2CCS(=O)(=O)C12)OCc1ccccc1 +CC1(C)C2CCC(CCN3C4CCC3CC(n3c(=O)c(C(=O)O)nc5ccccc53)C4)C1C2 +Cc1ccn(-c2ccc(C(=O)N3Cc4cccnc4Nc4ccccc43)c(Br)c2)n1 +O=C(NO)c1cnc(N2CC3C(C2)C3NCc2ccc(Cl)cc2)nc1 +Cc1ccc(C(CNC(=O)c2ccccc2C)CC(C)C)cn1 +NC(=O)c1ccc(NC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)cc1 +NC(=O)c1nn(-c2ccc3onc(N)c3c2)c2c(F)c(-c3ccc(N4CCCCC4=O)cc3F)ccc12 +COc1cc2oc(-c3ccc(O)c(O)c3)c(OC)c(=O)c2c(O)c1O +CSc1nnc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)n1 +Cc1ccc(CN2C3CCC2CC(=CCOC(c2ccccc2)c2ccccc2)C3)cc1 +CCN(CC)CCc1c[nH]c2ccc(NS(=O)(=O)c3cccc4c(Cl)cccc34)cc12 +CCC(CN(c1ccccc1F)S(C)(=O)=O)N1C(=O)C(CC(=O)O)OC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CCNCC(C)(C)COc1cccc2ccc(-c3nnc4ccccn34)nc12 +O=C(OCc1ccccc1)N1CCCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +O=C(Nc1ccc(C(=O)N2CC3CSCCN3Cc3cccc(Cl)c32)cc1)c1ccccc1-c1ccccc1 +COc1cc(OCc2cccc(-c3cnn(C)c3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CN1CC(CO)C=C2c3cccc4[nH]cc(c34)CC21 +Cc1cccc(Cl)c1Nc1nc2cc3c(cc2n2cncc12)OCCO3 +CC1(C)CCC(C(N)=O)N1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 +CC(=O)OCC1OC(CC(=O)C=Cc2ccc(Cl)c(Cl)c2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +Nc1nc(N2CCN(Cc3c(Cl)cncc3Cl)CC2)nc2nc(-c3ccco3)nn12 +Nc1ccncc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1 +CCc1nn(C2CCCC2)c2c1CCn1c(-c3ccccc3OC)nnc1-2 +CNC(=O)N1CC=C(c2cc3c(-c4cccc(F)c4F)ccnc3[nH]2)CC1 +O=C(Nc1cccnc1)c1cc(Br)ccc1OCc1ccccc1F +CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC(CC)(CC)CC2 +CC1CN(Cc2cccn2S(=O)(=O)c2ccccc2)CCC1(C)c1cccc(C(N)=O)c1 +CCc1nnc2n1CCN(C(=O)c1cccc(C(F)(F)F)c1Cl)C2 +NC(=NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccccc1F +CC(c1ccc(-c2ccc(=O)n(C)n2)cc1)N1CCC(CC(C)(C)O)(c2ccc(F)cc2)OC1=O +CC1(c2cc(NC(=O)c3ncc(Cl)cc3F)ccc2F)N=C(N)OCC1F +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cn5cnc6ncccc65)C4)cc23)ccn1 +O=C(Cc1cccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)c1)NN1CCNCC1 +Cc1ccc(C(=O)Nc2ccc(C(=O)N3CCCC3C(N)=O)cc2)cc1 +O=C1N(Cc2ccccc2)c2cscc2S(=O)(=O)N1Cc1ccccn1 +Nc1c(S(=O)(=O)O)cc(Nc2cccc3ccccc23)c2c1C(=O)c1ccccc1C2=O +CC(C)n1c(-c2ccnc(N)c2)nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +Cn1cc(-c2cnc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +CCN(CC)Cc1cccc(C=Cc2nc3ccc(F)cc3c(=O)n2-c2ccccc2Cl)n1 +Cn1cncc1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 +Cc1c(C(=O)Nc2cccc(F)c2)nnn1-c1ccc(C(C)C)cc1 +COc1cc2c(cc1OC)C(=O)C(C1CC[N+](C)(Cc3ccccc3)CC1)=C2 +CCC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(C)c1)CC1CCC(C(=O)O)CC1 +CSc1ccc(CN(C)CCOc2ccc(NC(=O)c3cccc4c(O)c5ccccc5nc34)cc2)cc1 +COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC1CC2OCC(OC)C2O1 +Cc1cccc(C2=NC(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)C(=O)Nc3ccccc32)c1 +CC=CCCC1C(C(=O)O)C(c2ccc3c(c2)OCO3)CN1CC(=O)N(CCCC)CCCC +O=c1sc2ccccc2n1CCCCN1CCN(C2CCCCC2)CC1 +CN1Cc2ccccc2N(C)c2nc(Nc3ccc(C(=O)N4CCC(N5CCCCC5)CC4)cc3Cl)ncc21 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CN(S(=O)(=O)C(C)C)C1)CC2 +OC1c2ccccc2CC1N1CCC(c2cccc3c2OCCO3)CC1 +Oc1cc2c(cc1O)C1c3ccc(O)c(O)c3OCC1(O)C2 +COc1ccc(OC2CN(c3ncnc4c3c(CC(C)C)nn4C)C2)cc1 +O=C1Cn2c(Cl)cnc(c2=O)NC(Cc2ccccc2)CNC(=O)OCCCCOc2ccc(Cl)cc2CN1 +COc1cccc2c(C(=O)NC(Cc3ccccc3)c3ccon3)c(C)n(CCN3CCOCC3)c12 +Nc1ncc(-c2cncc(NS(=O)(=O)c3ccccc3)c2)cn1 +COc1cc(OCc2csc(C3(O)CC(C)OC(C)C3)n2)c2cc(-c3cn4nc(C(C)F)sc4n3)oc2c1 +[N-]=[N+]=NCC1OC(n2c(SCC(=O)NCCc3c[nH]c4ccc(Cl)cc34)nc3c(N)ncnc32)C(O)C1O +CON(C)C(=O)C(=O)Nc1ccc(CNC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 +CSc1cccc(NC(=O)N2CCC(C(NC3CCC(c4c[nH]c5ccccc45)CC3)C(N)=O)CC2)c1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC3CN(c4nccc(-c5ccccc5)n4)C3C2)c1 +COc1cc(C(F)(F)F)ccc1-c1nc(Cl)cc2cc(S(=O)(=O)Nc3nccs3)ccc12 +CC(C)OC(=O)C1=CN(C(=O)c2ccc(OCCN3CCOCC3)cc2)CC(C)(C)c2c1[nH]c1ccccc21 +COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +COc1cc(-c2cc(F)cc(F)c2)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +Fc1ccc(C(Cc2ccccc2OC(F)(F)F)N2CCNCC2)cc1 +O=C(NC(=S)NCCC1CCN(Cc2ccccc2)CC1)c1ccccc1[N+](=O)[O-] +CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C#N +O=S(=O)(c1ccc(-c2ccc3c(Nc4ccc(OCc5ccccc5)c(Cl)c4)cnnc3c2)cc1)N1CCOCC1 +CN(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)CCC1c2ccccc2-c2ccccc21 +CCCc1nc2c(C)cc(C(=O)NCCc3ccc(F)cc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1ccccc1Nc1ncc(C(=O)NCc2ccccc2)c(C(F)(F)F)n1 +O=C(O)COc1ccc(-c2ccc(Cl)cc2)cc1C(=O)c1cnn(-c2ccccc2)c1 +CCc1c(C)nc(N2CCN(c3ccccc3F)CC2)nc1O +Cc1cc(S(=O)(=O)NC(=N)Nc2ccccc2S(N)(=O)=O)c(SCc2ccccc2)cc1Cl +CNCc1cn2c(-c3c[nH]c4ccccc34)cc(-c3ccc(F)cc3Cl)c(C#N)c2n1 +CN=C(S)C1c2cc([N+](=O)[O-])ccc2OC(C)(C)C1O +OC1CCN(C2(c3cc4ccccc4s3)CCCCC2)CC1 +CC12CCC(O)CC1CCC1C3CC4OC5(CC(C)(C)C(C)(C)O5)C(C)(O)C4C3(C)CC(O)C12 +Oc1nc2ccccc2cc1C(C#CC1CC1)(OCc1ccccc1)C(F)(F)F +Oc1cccc(Nc2nc(-c3ccccc3)nc3ccccc23)c1 +COc1ccc(-c2nc(O)n(C3CCN(Cc4ccccc4)CC3)c2C)cc1 +Cc1ccc(-c2c(NS(=O)(=O)c3ccc4ccccc4c3)ncnc2OCCOc2ncc(Br)cn2)cc1 +Clc1c(N2CCN(c3ccccc3)CC2)ccn2c(CC3CC3)nnc12 +COCCOc1cc(C#N)cc(-c2ccc3ccc(C)nc3c2)c1 +COc1ccc(-n2cnc3c(-c4cccc(OC)c4)csc3c2=O)cc1 +COc1cc(C(=O)Nc2cncc(C(=O)c3cn(C(C)C)c4ncncc34)c2)nc2c(C)nccc12 +[H]C([H])([H])c1c(Br)c2c(c(C([H])([H])[H])c1Br)C=C(C(=O)O)C(C(F)(F)F)O2 +COc1ccc(Cn2cc(-c3cc(C(F)(F)F)nc(S(C)(=O)=O)n3)ccc2=O)cc1OC +FC(F)(F)C(=S)NC1CCCN2c3cc(Cl)ccc3Oc3ccccc3C12 +CC(NC(=O)C1CC(F)C1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(O)C2)cc1 +Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccccc3)C2=O)cn1 +CC(=O)N1CCN(c2nc3c(c(N(C)Cc4cc5ccccc5cn4)n2)CN(C(C)C)C3=O)CC1 +COc1cc2c(Nc3ccc(OC4CCCCC4)cc3)c(C#N)cnc2cc1OCCCN1CCOCC1 +CCC(=O)Nc1ccc(C2=NC(=O)C(=Cc3ccc(OC)cc3)S2)cc1 +CC(C)(CNC(=O)c1cccc(C(F)(F)F)c1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +CC(C)CN1CCCCN2C(=O)c3c(O)c(=O)c(C(=O)NCc4ccc(F)cc4)cn3CC12 +CC1(C)C(=O)NN=C1c1ccc(NC2=C(Cc3ccccc3Cl)C(=O)CCC2)cc1Cl +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCCCC2CCCCC2)cc1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCN(c3ccc(C(F)(F)F)cn3)CC1)C(O)C2 +CC(NC(=O)c1cncs1)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 +NS(=O)(=O)c1cc(C(=O)NCc2ccccc2)c(Cl)cc1S +O=c1[nH]c2c(S(=O)(=O)c3ccccc3)csc2c(=O)n1O +CC(C)(C)C1(O)CCN2CC(c3ccccc3)CCC2C1 +O=C(NCc1ccccc1)OC1COC2C(OCc3ccccc3)COC12 +COc1ccc2c(c1)CN(C(=O)c1ccccc1)CCS2 +Cc1ccc2ncn(-c3ccnc(NC(C)c4ccccc4)n3)c2c1 +CC(=O)Nc1ccc(CCc2nc3cc(-c4c(C)noc4C)ccc3n2CCN2CCOCC2)cc1 +NCCCN(CCCCN(CCCNCCCc1ccccc1)CCCc1ccccc1)CCCc1ccccc1 +O=C(c1ccccc1C(F)(F)F)N(CC1CCCC1)C1CCNC1 +CCC(C)C(NC(=O)OCc1ccc(C(=O)O)cc1)C(=O)NC(CC(C)C)C(=O)NC(CC(F)F)C(=O)C(=O)O +COC1(C)CCC2(CC1)NC(=O)C(c1cc(-c3ccc(Cl)cc3)ccc1C)=C2O +N#Cc1ccc(-c2nc(NCCNc3ccc([N+](=O)[O-])cn3)ncc2C(=O)OCc2ccccc2)cc1 +COC(=O)C1C(c2ccc(Br)c(Br)c2)CC2CCC1N2C +CC(C)c1nc2cccnc2n1-c1ccc(CC(NC2=C(Br)C(=O)C23CCCCC3)C(=O)O)cc1 +CC(C)(C)c1[nH]nc2c1C(c1ccccc1O)N(c1ccc(-c3ccon3)cc1)C2=O +Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCC[S+]([O-])c3ccccc32)cc1 +Cc1ccc(C(=O)NC2C3(C)CCC(C3)C2(C)C)cc1CCN1CCOCC1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)Nc3ccc(F)c(F)c3)CC2)C1 +CC(C)NC(CN(c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1)S(C)(=O)=O)C(=O)NO +CC(C)c1n[nH]c2c(NCc3ccc(-c4ccccn4)cc3)nc(NCC(C)(C)O)nc12 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(F)cc1Oc1c(C)cc2ccccc2c1Cl +NS(=O)(=O)c1ccc(CNC(=O)Cn2ccnc2[N+](=O)[O-])cc1 +CN(C)c1ncc(Oc2ccc(S(=O)(=O)Nc3ccc(F)cn3)cc2C#N)cc1Cl +CNC(=O)c1c[nH]c2ccc(N3CCCc4cc(-c5cnn(C)c5)c(C(F)F)cc43)cc12 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCC2)cn1 +CN(C)CCOCC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1 +COC(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(CN2CCCC2=O)cc1)c1ccccc1 +CCCCc1ccc(-c2ccc3cc(-c4ccc(C(N)=O)cc4)[nH]c3c2F)cc1 +CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(=O)NNS(=O)(=O)c1ccc2ccccc2c1)CC(C)C +CC(C)n1nc(-c2cnc(N)c(C(F)F)c2)cc1C1C2CN(C3COC3)CC21 +CCn1c(CC(=O)Nc2ccc(F)cc2)nc(N2CCOCC2)cc1=O +CS(=O)(=O)c1ccccc1C(=O)NCC(O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1 +COc1ccc(N(CC(O)CO)c2cc(-c3c[nH]c4ncc(-c5cnn(C)c5)cc34)nc(N)n2)cc1 +COCCN(CCc1ccc(F)cc1)c1cc2nc(-c3ccco3)nn2c(N)n1 +CN(C)C1(C(=O)Nc2cccc(-n3ccnc3)c2)CCN(c2ncnc3[nH]c4c(c23)CCCC4)CC1 +COc1ccc(Nc2nc(N)c(N=O)c(OCC3CCCCC3)n2)cc1 +CCc1nnc(NC(=O)C2(CC(CCc3ccccc3)C(=O)O)CCCC2)s1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCC(C)F +CC(C)NC(=N)c1ccc(OCc2ccc3c(COc4ccc(C(=N)NC(C)C)cc4)cccc3c2)cc1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC1CCC(=O)NCCCC(O)C(O)C(CC2CCCCC2)NC1=O +COCC1CCCN1c1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(-c2ccccc2)n1 +CC1(CS(=O)(=O)c2ccc(Cl)cc2)COC2(CCCC2)OO1 +COc1ccc(Cl)cc1CNc1ncnc2c1ncn2C1OC(CO)C(CN)C1O +CCc1ccc(-n2cnc3c(sc4nccc(NC)c43)c2=O)cc1 +O=C1CC(c2ccc(O)cc2)Oc2c1ccc1ccccc21 +CCOC(=O)N(C)CC1=Cc2ccc(NC(=O)c3ccc(-c4ccc(Cl)cc4)cc3)cc2CC1 +Clc1ccc(CCC2(Cn3ccnc3)OCC(CSc3ccc(Br)cc3)O2)cc1 +O=C(NC1CCCCC1NS(=O)(=O)c1ccc(-n2ccccc2=O)cc1)c1ccc2c(Cl)c[nH]c2c1 +Cc1cc(NC(=O)C(C#N)=C(O)C2CC2)ccc1OC(F)(F)F +CC(C)n1ncc2cc(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)ccc21 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cccc(C)c2[nH]1)C(F)(F)F +O=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1nc(Cl)c(Cl)[nH]1 +NCc1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)s1 +CC1CC2C(C1)C2(c1ccc(F)cc1)N1CCN(c2ccccc2)CC1 +CC1(c2sc(-c3cncc(C#N)c3)cc2Cl)CS(=O)(=O)C2(CCOCC2)C(=N)N1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)NCc2ccncc2)c1=O)C(=O)C(F)(F)F +CCCn1c(=O)c2nc(-c3ccc(C#N)cc3)[nH]c2n(C)c1=O +OC1(CCCc2cccnc2)CCN(CC2CN(CC3CCCCC3)CC2c2ccccc2)CC1 +CC(C)c1onc(-c2ccccc2Cl)c1C(=O)N(C)c1ccc(Cl)cc1 +O=C(Nc1cc(-c2cc3c([nH]2)C2(CCCNC2)CNC3=O)ccn1)c1cccc(F)c1 +CN1CCN(Cc2cc3cc(-n4cnc5cc(-c6ccc(Cl)cc6)sc5c4=O)ccc3s2)CC1 +N#Cc1ccc(CC(=O)Nc2cncc(C(=O)c3cn(C4(CO)CC4)c4ncncc34)c2)cc1 +Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nc(-c5cccnc5)cs4)c3)cc(C(C)C)c2)cn1 +COc1ccc(-c2oc3c(O)c(O)ccc3c(=O)c2O)cc1OC +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C1CCCC1)CC2 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCN(Cc2cccc3c2ccn3C)C1 +O=C1C(=O)N(CCCn2cc(COc3ccc(C=NNc4ccnc5cc(Cl)ccc45)cc3)nn2)c2ccc(F)cc21 +N#CC1CCCN1C(=O)CNC1CCN(c2ccc(C(F)(F)F)cn2)CC1 +Cc1cc(C)c(NC(=O)N(Cc2ccc(-n3ccnc3)cc2)C2CCCCCC2)c(C)c1 +O=S(=O)(NCCCN1CCN(c2nsc3ccccc23)CC1)c1cccc2scnc12 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(C(=O)O)n(C)c(=O)c3ccccc23)cc1 +COc1ccc(-c2cnc3c(N(C)C)snc3c2)cc1OC +O=C(Nc1cccc(-c2cccnc2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 +COc1cc(OCc2csc(C3(c4cccc(Cl)c4)CCOCC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(c1cccc2cc(N=C=S)ccc12)c1cn(CCN2CCOCC2)c2ccccc12 +O=C(O)c1ccc2c(c1)C(=CCn1cnc3cc(C(=O)NCc4ccccc4)ccc31)c1ccccc1CO2 +COc1cc(NC(=O)c2nn3c(C(F)(F)F)cc(-c4ccc(Br)cc4)nc3c2Cl)cc([N+](=O)[O-])c1 +c1ccc(COc2cccc(C3CC(c4ccc5c(c4)OCCO5)=NN3c3ccccc3)c2)cc1 +COc1ccc(S(=O)(=O)Nc2c(C)cc(Cl)cc2C)cc1 +CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3ccc(Cl)cc23)c1 +CCCCCCCCCCC1(C(=O)Nc2c(C)ccc3c2OCCC3=O)CCCC1 +COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1c(C)[nH]c3ccccc13)CC2 +CCN(C(=O)SCC(=O)Nc1ccc(-c2ccc(CC(=O)O)cc2)cc1Cl)c1ccc(C(C)(C)C)cc1Cl +CS(=O)(=O)Nc1ccccc1-c1ccc2[nH]c(C=Cc3ccc(C(F)(F)F)cc3)nc2c1 +CN(C)c1ccc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)cn1 +COc1cc(Nc2cc(-c3ccccc3)nc3c2C(=O)NCC3)ccc1C(=O)O +CC1C(c2ccc3c(c2)NC(=O)CO3)=C(c2ccc(F)cc2)C(=O)N1C 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+Cc1ccc(N2C(=O)C(NC(=O)C(=O)NCCCNc3ccnc4cc(Cl)ccc34)C2C=Cc2ccccc2)cc1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2cccc(F)c2)CCN(C(=O)C(C)(C)C(=O)O)CC1 +CN1CCC(C(=O)Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)CC1 +CC(C)=CCCC(C)=CCCC(C)=CCCSC(C)CCC=C(C)CCC1OC1(C)C +Cc1ccc(-c2cncc(N3CC4CC(C3)N4)c2)cc1 +COCC(Nc1ncnc2c1CN(c1ccc(C)cc1C#N)CC2)c1ccc(OC)nc1 +O=C(O)CC(NC(=O)c1cccn2c(C=CC3CCNCC3)nnc12)c1cccnc1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCc1cccc(N(C)C(=N)N(C)c2cc(Cl)ccc2Cl)c1 +O=C(NCCN1CCOCC1)c1ccc(N2CCC(NC(=O)N3CCN(C(=O)c4ccc[nH]4)CC3)CC2)cc1 +O=c1cc(OCc2ccccn2)ccn1-c1ccc2c3c([nH]c2c1)CC1CCC3N1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(Cl)cc1-c1ccnnc1 +CCN1Cc2c(ccc(Nc3ncc(C(F)(F)F)c(NC)n3)c2OC)C1=O +CCn1c(SCC(=O)c2ccccc2)nc2sc3c(c2c1=O)CCN(C)C3 +Cc1cc(Br)ccc1OCc1sc2ccccc2c1CCN1CCC(N(C)C)CC1 +Cc1ccc(CCC[N+]23CCC(CC2)C(OC(=O)C2(C4=CC=CC4)CCCCCC2)C3)cn1 +CCOc1cc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(Cl)c3)c2cc1NC(=O)C(F)=CCN1CCCCC1 +CCOC(=O)C1=C(N2CCc3ccc(OC)cc3C2)OC(=Cc2c[nH]c3ncccc23)C1=O 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+C=CC(=O)Nc1cc(Nc2cc(-c3cn(C)c4ccccc34)ncn2)c(OC)cc1N(C)CCN(C)C +COc1cccc(CCC(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)c1 +COc1cnc2c(C(=O)NCCF)cn(Cc3ncnc(OC(F)F)c3C)c2c1 +CCCCC1N(Cc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)C(=O)c2cc(C(C)C)ccc2N1C +CCOc1cc(OCc2cccc(OCc3ccccc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CCc1c2nc(-c3cc(S(=O)(=O)N4CCN(CC)CC4)cnc3OCCOC)[nH]c(=O)c2nn1C1CCC1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(CN2CCn3cnnc3C2)cc1 +CN1CCN(Cc2ccc(NC(=O)c3ccc(Cl)c(NC(=O)c4cccc(-c5cccs5)c4)c3)cc2C(F)(F)F)CC1 +O=C(O)Cn1ccc2ccc(OCCCOc3ccc(C(=O)c4ccc(F)cc4)cc3)cc21 +CC(C)CC(NC(=S)Nc1cccc(C#N)c1)C(=O)NC1CCOC1O +[N-]=[N+]=NC1(CO)OC(n2ccc(=O)[nH]c2=O)CC1O +CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(C)nc(NC(C)=O)nc3C)CC2)CC1 +CC(C)Oc1ccc(Nc2nc(=O)n(CC(CO)CO)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +O=c1[nH]c(C2CCCN2)nc2c1oc1ccc(Cl)cc12 +Cc1c(CCC(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)cn1C(C)C +O=c1ccc2cnc3ccc(-c4cnc5ccccc5c4)cc3c2n1-c1ccc(F)c(Cl)c1 +CCN(CC)C(=O)c1ccc(C(=C2CCN(Cc3ccc(F)cc3)CC2)c2cccc(F)c2)cc1 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+COc1ccc2[nH]cc(CC(=O)N3CCN(c4scnc4-c4nc5ccccc5[nH]4)CC3C)c2c1 +CCOc1ccc(C2=NN(c3ccc(C(=O)O)cc3)C(=O)C3CC=CCC23)cc1OCC +CN1C(=O)N(c2ccnn2C)CC1C(=O)NCc1ccc(Cl)cc1Cl +O=C(O)c1nc2c(=O)[nH]c3cc(Cl)c(-n4cccn4)cc3n2n1 +O=C(Nc1ccc(I)cc1)Oc1ccc2c(c1)C13CCCCC1C(C2)N(CC1CCC1)CC3 +CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2cccc(CNC(=O)CNS(C)(=O)=O)c2)n1 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)CCCc4ccccc4)c3)cc12 +N#Cc1cc(Oc2ccc(-c3cc(C(O)CO)cc(C(N)=O)n3)cc2)ccc1C(F)(F)F +O=C(Nc1ccc(C(F)(F)F)cn1)N1CC=C(c2ncc(-c3nnc(CO)o3)cc2Cl)CC1 +CC(=O)Nc1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)cc(C(F)(F)F)c1 +OC1CCN(Cc2cnc3cc(Oc4ccc(-c5ccn[nH]5)cn4)ccc3c2)C1 +O=C(O)c1cccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2sc3ccccc3c2Br)c1 +O=C(O)C1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 +Cc1ccc2c(OCCN3CCC(Cc4cccc(NC(=O)C(C)C)c4)CC3)cccc2n1 +O=C(NCc1cc([N+](=O)[O-])ccc1O)c1cccnc1Sc1ccccc1Cl +O=C(Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)C1CC1c1cccnc1 +CC(C)CC(NC(=O)CC(NC(=O)c1ccc2ccccc2c1)c1cccc(Cl)c1)B(O)O 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+O=C(O)CC(NC(=O)CN1CCN(CCc2ccc3c(n2)NCCC3)C1=O)c1cccnc1 +FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2cc(Cl)cc(Cl)c2)c2ccccc23)cc1 +CN1CCN(Cc2cccc(C(=O)C=Cc3cccc(C=CC(=O)NO)c3)c2)CC1 +Cc1cc(S(=O)(=O)NC(=N)NCc2ccc(S(N)(=O)=O)cc2)c(SCc2cc3c(cc2Cl)OCO3)cc1Cl +O=c1sc2ccccc2n1CCCCCCN1CCN(CCCCCCn2c(=O)sc3ccccc32)CC1 +CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C(F)(F)F)cc1)CCC3 +Cn1c(=O)c2nc(-c3ccccc3)[nH]c2n(C)c1=S +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cccc(N2CCC(O)(C(F)(F)F)CC2)n1 +CN1CC2CC1CN2c1ccc(-c2ccc3[nH]ccc3c2)cn1 +CC(=O)NC(C)c1ccc(OC2CCN(c3cc(OCC4CC4)ncc3C)C2)cc1 +CC(Nc1ncnc(N)c1C#Cc1ccccc1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +COc1cc2c(cc1OCc1ccncc1)Cc1c-2n[nH]c1-c1ccc(C#N)cc1 +CC(C)Cc1cc2c(cc1Cl)C=C(C(=O)O)C(C(F)(F)F)O2 +Cn1cncc1C(O)(c1ccc2nc(Cl)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1)c1cncs1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(F)c1F +CCC(CO)Nc1nc(NCc2cccc(OC)c2OC)c2ncn(C(C)C)c2n1 +Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NCc2ccccn2)C3)c1-c1ccc(C(F)(F)F)cc1 +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4cc(O)c(OC)cc4[nH]3)CC3CC123 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+COCC(C1CC1)n1nc(C)nc(Nc2c(Cl)cc(C(F)(F)F)cc2Cl)c1=O +COc1ccc(S(=O)(=O)N(Cc2ccccc2)c2c(C)cc(C)cc2C(=O)NO)cc1 +NS(=O)(=O)c1ccc(O)c(NC(=[Se])NC(=O)c2ccc(-c3ccccc3)cc2)c1 +CC(NP(=O)(COC1C=C(F)C(n2cnc3c(N)ncnc32)O1)Oc1ccccc1)C(=O)OC1CCCC1 +O=C(NC1CCCC(NC(=O)c2ccccc2F)C1)c1cccc(Cl)c1 +CC(Oc1nc(-c2ccc3c(c2)C2(CCN(C)CC2)C(=O)N3)cnc1N)c1c(Cl)ccc(F)c1Cl +CN1CCN(c2cccc(CNCCc3ccc(NC(=O)Nc4cnc(C#N)cn4)cc3Cl)c2)CC1 +N#Cc1nc(NC2CC3CCC2C3)c(N)c(N2CCOCC2)n1 +CC(C)(C)c1ccc(S(=O)(=O)CCNc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1cc(NC(=O)c2ccc(C3CCCN3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C +COc1cc2c(cc1O)CCC1C2CCC2(C)C(c3cccnc3)CCC12 +CC(C)Cn1c2ccc(C(=O)c3sccc3Cl)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +CC(NS(=O)(=O)CCCn1ccc(=O)[nH]c1=O)c1ccc(F)c(OCC2CC2)c1 +CCOC(=O)C=CC(=O)N(CC(N)=O)NC(=O)C1CCCN1C(=O)C1CCCCN1C(C)=O +Cc1ccc(-c2nn(-c3ccccc3)cc2C(=O)Nc2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)cc1 +FC(F)(F)C1(c2nnc(-c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3Cn3cncn3)s2)CC1 +CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(C2CCC(OC)CC2)c2ncnn12 +COc1cc(Cl)ccc1-c1nc(NCCNc2ccc([N+](=O)[O-])c(N)n2)ncc1-c1ncc[nH]1 +O=C1N(Cc2ccccc2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc2ccccc2c1 +CCC(C)C1=NC2CC=C3CC4C(=O)CC5(C)C(C(C)N(C)C)C(O)CC5(C)C4CCC3C2(C)CN1 +CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(F)c[n+]3[O-])c2)CC1 +CNC(=O)Nc1ccc(Oc2ncnc(N)c2C=NOC)c(F)c1 +Cc1ccc(O)cc1Nc1cc(C(F)(F)F)nc(-c2cccnc2)n1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CC3)CC2)c1)c1ccc(F)cn1 +CC(=O)NC1CCN(CC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)C1 +CC1CN(c2nc(N3CCOCC3)c3sc(-c4cccnc4)cc3n2)CC(C)O1 +CC(Cc1ccccc1)n1c(-c2ncccc2O)nc2ccnc(C(F)(F)F)c2c1=O +O=C(Cn1nnc(-c2ccncc2)c1-c1ccccc1)Nc1cccc(-c2ccccc2)c1 +CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3O)c(=O)n2C1c1ccc(OC)c(OC)c1 +CN(C)CCN(Cc1ccco1)C(=O)c1cc2c(Cl)nc3ccccc3c2s1 +CC(C)(C(=O)N1CCC(CC(=O)O)CC1)C(NC(=O)c1ccc(C(=N)N)cc1)c1ccc(O)cc1 +c1cc(COc2cccc(-c3nn[nH]n3)c2)cc(OCc2ccc3ccccc3n2)c1 +CCCOc1ncc(C(C)=O)cc1-c1nc(O)c2nn(C3CCN(CC)CC3)c(CC)c2n1 +c1ccc2c(c1)[nH]c1nccc(NCC3CCCCC3)c12 +CCNc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 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+COCCOc1ccc2[nH]c(C(=O)c3cnn(-c4ccc5[nH]c(C)nc5c4)c3N)cc2c1 +Cc1cc(C(=O)O)nn1Cc1cc(Cl)ccc1OCC(C)C +O=c1[nH]c(-c2ccc(C(F)(F)F)cc2)nc2c1CCCC2 +Cc1cccc(-c2nc(N(C(N)=O)c3c(F)cccc3F)c3ncn(C)c3n2)c1 +COc1cccc(Cn2cc(C)c3ccc(C(=O)Nc4c(Cl)cncc4Cl)cc32)c1 +COc1cc2c(cc1OC)SC(C(=O)CCc1cc[n+](CC3CCC3)cc1)C2 +Cn1ncc(C(=O)c2ccc3c(c2)n(C2CC2)c(=O)n3C)c1O +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)n[nH]2)cc1Nc1ncnc2cnc(N3CCCN(C)CC3)nc12 +O=C(O)COCC1CCN(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +Cc1ccc(C)c(CN2CCCC(C(=O)N(Cc3cc(Cl)c4c(c3)CCCCO4)CC(C)C)C2)c1 +Cn1cnc2c(C(=O)NC3CCCCC3)cc(NC(=O)c3ccccc3C(F)(F)F)cc21 +CC(C)(CC(O)(CC1CCCCC1)C(=O)Nc1ccc2c(c1)COC2=O)c1ccccc1 +COc1cc(OC)cc(C(=O)NCC(=O)OCc2nc3ccccc3s2)c1 +COc1cc(C#N)cc(Oc2c(Cl)ccc(Cc3cc(C)c(=O)[nH]n3)c2F)c1 +CCc1cccc(N(C)C(=N)Nc2cc(Cl)ccc2Cl)c1 +CCS(=O)(=O)Nc1ccc(CCNC(=O)c2ccnc3[nH]c(-c4ccccc4)nc23)cc1 +CC(C)C1(c2c[nH]c(-c3ccc4ccccc4c3)cc2=O)OC(=O)NC1=O +Cc1c(C(O)CN2CCC3CN(CC(O)c4ccc(C#N)cn4)CC32)ccc2c1COC2=O +S=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)Nc1ccccc1 +COc1ccc(C(=O)C=Cc2ccc(Cl)cc2Cl)c(OC)c1OC +NC1CN(C(=O)c2cnc3ccccc3n2)CC1C(=O)N1CCCC1 +CC1(C)CC(O)CC(C)(CNc2cccc(C(F)(F)F)n2)C1 +COc1ccc(-c2csc(-c3nc4c(=O)n(C)c(=O)nc-4n(C)n3)c2)cc1OC +COCCN(CCOC)c1nn2c(-c3ccc(O)cc3)nnc2c2ccccc12 +CCN1CC(c2ccc(F)cc2)N2C(=O)C(=Cc3ccc(-n4cnc(C)c4)c(OC)c3)N=C12 +O=C(C1CC(n2cc(-c3ccccc3)nn2)CN1C(=O)OCc1ccccc1)N1CCCC1 +O=[N+]([O-])c1cc(O)c(O)c([N+](=O)[O-])c1 +CCN(CC(=O)N(C)C)C1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 +CCOP(=O)(OCC)C(Nc1ccc(CCC(=O)NC23CC4CC(CC(C4)C2)C3)cc1)C(C)(C)C +Cc1cc(C#N)cnc1Nc1cc(NC(C)C)c(C(=O)NCC(F)C(C)(C)O)cn1 +NC(=O)C(CO)NC(=O)C(CCC(=O)O)NC(=O)CCc1ccc(-c2ccc(-c3ccccc3)cc2)cc1 +N=C(N)c1ccc(-c2ccc(-c3ccc([N+](=O)[O-])cc3)o2)cc1 +CCOC(=O)C(=NNc1ccccc1F)C(=O)c1cc(C)nn1CC +CCOC(=O)c1cnc(-c2ccc(OC)cc2)nc1NN1C(=O)C=C(C)C1=O +Cc1cc(COc2ccc(S(=O)(=O)CC3(CC(=O)NO)CCCN(C(C)C)C3)cc2)c2ccccc2n1 +O=C(c1ccc(OCCCN2CCN(C(=O)CC3CCCN3)CC2)cc1)C1CC1 +Cn1c(C(=O)C2CCN(C3Cc4ccccc4CC3O)CC2)cccc1=O +Cn1c(=O)c2c(nc3n(CCCCCN4CCN(c5ccccc5O)CC4)ccn23)n(C)c1=O +C1=CC(c2cccnc2Oc2ccc(Nc3ccccn3)cc2)CO1 +CCCCc1nc2cc(S(=O)(=O)NCC)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COC1OC2(c3ccc(COCc4ccc(F)cc4)cc3)CCC3CCCCC31OO2 +COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1NCCCN(C)C +COc1cc(Nc2nc(NC3CCCCC3N)n3nc(-c4ccccc4Cl)nc3c2C(N)=O)cc(OC)c1 +CCN(c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)C(C)c1ccccc1 +COc1ccc(NCCNC(=O)C(Cc2ccc(C(F)(F)F)cc2)NC(=O)c2cccc(C)c2)cc1 +O=C(O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(C4CC4)cn3)cc2)C1=O +COc1ncc(-c2ccc3ncn(C4CCN(CC5CC5)C4)c(=O)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1 +c1nc(CCCSC(=NC2CCCCC2)NC2CCCCC2)c[nH]1 +CC(C)c1cc(-c2nnc(O)n2-c2cccc(S(=O)(=O)N3CCOCC3)c2)c(O)cc1O +O=C(CC1CCCOC1)NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1 +COc1cccc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)sc3c2)c1 +Cc1ccccc1N1N=C(c2c(-c3ccc(F)cc3Cl)nc3ccccn23)CCC1=O +CCCCCCCC#Cc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +COc1ncccc1-c1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 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+CCCNC(=O)c1cccc(Oc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1 +O=C(c1ccc(Cl)cc1)N1CCN(c2ccc(OC3CCN(C4CCC4)CC3)cc2)C(=O)C1 +CS(=O)(=O)Nc1ccc(CN=C(S)NCc2ccc(Br)cc2)cc1F +CN1CCN(C(=O)c2cc3ccc(O)cc3[nH]2)CC1 +Cc1sc(C=Cc2cccc(C(CCc3ccccc3C(C)(C)O)SCC3(CC(=O)O)CC3)c2)nc1C(C)C +CN1CCN(C(=O)C2CC(S(=O)(=O)c3ccccc3)CC2C(=O)NC2(C#N)CC2)CC1 +COc1ccc(-c2ccoc2)cc1CNC1CCCNC1c1ccccc1 +COc1ccc(O)c(O)c1-c1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)ccc1N +O=C(NCC1CCCCN1C(=O)c1cccc2ccccc12)c1ccccc1 +O=C(NC1CCC(O)CC1)c1cnn2ccc(N3CCCC3c3cc(F)ccc3CO)nc12 +Cc1cc(C(=O)N2CC=C(c3ccc(NC(=O)N4Cc5ccncc5C4)cc3)CC2)n(C)n1 +CS(=O)(=O)NC1CCC(Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1 +Cc1cc(N=S(C)(=O)C2CC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NCC(F)(F)F)c12 +CC(C)Oc1cc(-n2nc(C(C)(C)C)oc2=O)c(Cl)cc1Cl +COc1cc2c(cc1OC)-c1[nH]nc(NCc3ccccc3Cl)c1C2 +COc1cc(CNc2ccc(C(=N)N)cc2)ccc1OCc1ccccc1 +Cc1cccc(C(=O)N2C3CCC2C(Nc2ncc(C(F)(F)F)cn2)C3)c1-n1nccn1 +FC(F)(F)c1cccc(Oc2ccc(Nc3ncnc4cc[nH]c34)cc2Cl)c1 +Cc1c(Cl)cccc1N1CCN(CCNC(=O)c2cc(C(C)(C)C)n(C)c2C)CC1 +O=C(O)c1cccc(Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 +COc1ccc(-c2noc(C)c2C(=O)N=C(N)NCc2cc(Cl)c(O)c(Cl)c2)cc1 +Cc1nc(=O)c(-c2ccccc2)c(C)n1-c1cccc(Br)c1 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1c(F)cccc1F)C(C)c1ccccc1 +O=C(O)C1(c2ccc3c(c2)CC(C(c2ccccc2)C2CCCCC2)C3O)CCCC1 +CCN(CCOc1ccc2c(c1)C(Cc1ccccc1)C(N)CC2)S(=O)(=O)c1cnn(C)c1 +CC(C)(O)C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(Cc2ccco2)CC1 +Cc1cccc(OC2CCN(C(=O)NC3CC3c3ccccc3)CC2)c1 +C(=Cc1ccccc1)CN1CCN(c2ncnc3c2oc2ccccc23)CC1 +Cc1cc(S(=O)(=O)NC(=N)NCc2ccc(S(N)(=O)=O)cc2)c(SCc2cccc(C(F)(F)F)c2)cc1Cl +C=CC=CC(=O)Cc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +O=C(NCCNc1cccc2cc(Cl)ccc12)NC1C(=O)N(C2CCCCC2)C1C=Cc1ccccc1 +CC(C)(C)c1ccc(OC(=O)N2CCc3c([nH]c4ccc(O)cc34)C2)cc1 +CC(C)CC1CC(=O)NC(CCCCN)C(=O)NC(CCCCCC(=O)O)C(=O)NC(Cc2cccc3ccccc23)C(=O)N1 +CN(Cc1nc2cccc(CCCN3CCCCC3)c2[nH]1)C1CCCc2cccnc21 +CN1C(=O)CCC2(C)C3CCC4(C)C(CCC4(O)C#CCCCI)C3CCC12 +CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1CN(C)C +O=C(Nc1cccc(-c2nc3ncccc3[nH]2)c1)c1ccco1 +CCCn1c(Br)nc2c(N)nc(NCCc3ccccc3)nc21 +COc1ccc(N2CCC(C)(c3ccc(Cl)c(Cl)c3)C2=O)cc1OCCN1CCCCC1 +CCCCCCCNC(=O)Oc1ccc2c(c1)CN(C)C(c1ccoc1)N2C +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc2nc[nH]c2c1 +N#Cc1ccc(-c2nc(-c3ccnc4ccccc34)c(-c3ccc(F)cc3)[nH]2)cc1 +COc1ccccc1C(CNC(=O)Nc1cc(Cl)cc(Cl)c1)N1CCN(C2CCCCC2)CC1 +CCCCCCCCC=CCCCCCCCCNC(=O)Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1 +COc1ncc(-c2ccccc2Cc2nc3c(cnn3C3CCOCC3)c(=O)[nH]2)cn1 +COc1ccc2[nH]c(CN(C)Cc3ccccc3)c(CCNC(C)=O)c2c1 +Clc1ccc2c(c1)c1cc[n+]2Cc2cccc(c2)C[n+]2ccc(c3cc(Cl)ccc32)NCc2ccc(cc2)CN1 +CC(C)Nc1nnc(-c2ccc3[nH]cc(NC(=O)c4ccncc4)c3c2)o1 +CC(=Cc1ccccc1)COC(=O)C1CCCCN1C(=O)C(=O)C1CCCCC1 +Cc1cccc(NC(=O)c2cc(F)cc(-c3ccccc3C)c2)n1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1CNC(C)CC(C)C +Cc1cc(C)cc(C2=CCN(C(=O)C3NCC4(CC4)CC3C(=O)NO)CC2)c1 +O=C1CN(Cc2ccccc2)CCN1CCCc1c[nH]c2ccc(-n3cnnc3)cc12 +CCCCCNc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 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+CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(Nc2ccc(C(F)(F)F)cn2)c1 +COc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C(F)=CCN(C)C +CCCOc1ccc(S(=O)(=O)N2CCN(CC)CC2)cc1-c1nc(O)c2cc3c(cc2n1)ncn3Cc1cccc(F)c1 +CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(O)CCc1ccccc1 +CCOC(=O)c1ccc(NC(=O)CSc2nncnc2-c2cccc3ccccc23)c(Cl)c1 +CC1(C)CCc2cc(S(=O)(=O)N(CC(=O)O)C3(c4ccc(-c5cc(Cl)cc(Cl)c5)cc4)CCOC3)ccc2O1 +Oc1ccccc1C1=NN(C(=S)Nc2ccccc2)C(c2cccs2)C1 +Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(=O)C3(C)CCCC3)C2=O)c1 +CN1C(=O)N(C2CCCC2)CC1C(=O)NCc1ccc(Cl)cc1Cl +Cn1cnc(S(=O)(=O)N(CCN(Cc2cncn2C)c2ccc(C#N)cc2)Cc2ccccc2)c1 +CC(=O)N(C)CC(O)CN1C2CCC1CC(NC(=O)c1cc3ccccc3n(C(C)C)c1=O)C2 +O=C(NCCNc1ccc(OC(F)(F)F)cc1)C(CC1CCCCC1)NC(=O)C1CCCO1 +CC(C)N(Cc1nc(-c2cccnc2)no1)C(=O)c1cc2ccccc2o1 +CCNC(=O)Nc1nc2ccc(-c3ccccc3Oc3ccccc3)cc2[nH]1 +Cn1cccc1C(=O)N1CCCC(c2nc(-c3ccccc3)no2)C1 +Cn1c(=O)n(CC2CC2(F)F)c2ccc(C3=CC4CCC3CN4C(=O)c3ccon3)nc21 +CCN1C(=O)C(Cc2ccccc2)CC1C(=O)NCc1ccc(F)cc1Cl +CCOC(=O)COC(=O)N1CCC(C#N)C(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)C1 +N=C(N)c1cccc(CC(CO)C(C=Cc2ccccc2)NC(=O)c2ccc(-c3ccccc3)cc2)c1 +C=CCn1c(CNC(=O)C2Cc3ccccc3CN2C(=O)C(N)Cc2c(C)cc(O)cc2C)nc2ccccc21 +CC(C)CC(C(=O)OCc1ccccc1)N1C(=O)C(N2C(=O)OCC2c2ccccc2)C1C=Cc1ccccc1 +COCCCOc1cc(C(=O)N(CC2CNCC2NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)C(C)C)ccc1OC +CCOc1c(C)cc(Br)cc1CNCCCNc1cc(O)c2ccccc2n1 +Cc1c(C(=O)O)cccc1-c1cc(Nc2cccc(N3CCCC3C)n2)c2nccn2n1 +CC(C)(C)c1ccc(NC(=O)c2scnc2CCc2ccncc2)cc1 +COCC(NC(=O)Nc1cc2[nH]nc(C(F)(F)F)c2cn1)c1ccccc1 +Cc1ccncc1-c1ccc2cc(NC(=O)C3CCN(C)CC3)ncc2c1 +COc1cc2c(cc1CNC1CCCNC1c1ccccc1)C(C(F)(F)F)CC2 +N#CC1(NC(=O)C2CC(S(=O)(=O)c3ccccc3)CC2C(=O)N2CC(O)C2)CC1 +O=C1NC(=O)C2=C1c1cn(c3ccccc13)CCOCCOCCOCCOCCOCCn1cc2c2ccccc21 +COc1cnc2c(C(=O)NCCO)cn(Cc3ncnc(N(C)C)c3C)c2c1 +[C-]#[N+]C1(NC(=O)c2cnc(-n3ncc4cc(C#N)c(N)nc43)cc2NC(C)C)CC1 +O=C(O)c1cccnc1Oc1ccc2c(c1)CC(NCC(O)c1cccc(Cl)c1)CC2 +CN(Cc1ccccc1)C(=S)Sc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] +O=C(CCCN1CCC(CO)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +CCCCCCCCCCCCOCC(C)OP(=O)(O)OCC1OC(n2cc(C)c(=O)[nH]c2=O)CC1N=[N+]=[N-] +CCCC(=O)NCc1nc(-c2nc(C)cs2)c(-c2ccc(O)cc2)[nH]1 +COc1cnc(-c2ccc(NC(=O)Nc3ccc(F)cc3)cc2)nc1N1CCOCC1 +COc1cccc(C(=O)NC(CCC2CCCCC2)C(=O)NC(Cc2ccccc2)CN2CCc3cc(F)ccc32)c1 +O=C(NCCO)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4ccccc4)c(F)cc3F)cc1CC2 +Nc1ncc(Cc2ccc(OCCCOc3cc(Cl)c(Cl)cc3Cl)cc2)c(N)n1 +CS(=O)(=O)Nc1ccc(CCNC(=O)c2ccnc3[nH]c(-c4ccc(F)cc4)nc23)cc1 +CCN(CC)C(=O)C1CCN(C(=O)Nc2cccc(Cn3nc(-c4cccc(Br)c4)ccc3=O)c2)CC1 +NCc1ccc(C(=O)Nc2ccncc2F)cc1-c1cccc(C(=O)Nc2cccc(C(=O)O)c2)c1 +Cc1nc(NC(C)c2cccc(OCc3csc(C)n3)c2)cc(-c2ccc3ncsc3c2)n1 +CN(C)CCn1ncc2cc(-n3ccc(OCc4ccccc4)cc3=O)ccc21 +OCCN1CCn2c(CCc3ccccc3)c(C(F)(F)F)c3cccc(c32)C1 +CCn1c(=O)n(C2CCN3C(CCCC3c3ccccc3)C2)c2ccccc21 +CN(C)c1ccc(C=Cc2nc3ccc(I)cc3[nH]2)cc1 +COc1cc(Nc2c(C#N)cnc3cc(-c4cccc(CCN5CCOCC5)c4)c(OC)cc23)c(Cl)cc1Cl +CC1(O)CCC2C(CCC3C2CCC2(C)C(C(=O)Cn4nccn4)CCC32)C1 +CC1CN(C2CCC(C#N)(c3ccc(F)cc3)CC2)CCC1(C(=O)O)c1ccccc1 +CCN(C(=O)c1ccc(Cl)cc1)C1CCN(C(C)CC(NC(=O)C2CCC2)c2ccccc2)CC1 +C=Cc1cccc2c1C(=NO)C(=O)N2Cc1cc(F)cc2c1OCOC2 +CC12CCC(=O)C=C1CCC1C2=CCC2(C)C1CCC2(O)C(=O)CO +COc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(COC(=O)c1cccc([N+](=O)[O-])c1)C2 +CN(C)CCCNC(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CC(C)c1n[nH]c2c(NCc3ccc(-c4ccccn4)cc3)nc(NCCN)nc12 +COc1ccc(CC(=O)NC2CC(C(=O)O)Nc3cc(Cl)cc(Cl)c32)cc1 +NC1(c2ccc(-c3nc4n(c3-c3ccccc3)COc3cccc(F)c3-4)cc2)CCC1 +O=C(Nc1cn(CC(=O)N2CCN(Cc3ncco3)CC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +O=C1Cn2c(Cl)cnc(c2=O)NC(Cc2ccccc2)CNCCOc2ccc(Cl)cc2CN1 +CCC1(CC)C(=O)Nc2ccc(-c3ccc(C#N)n3C)cc21 +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(Oc2ccc(OCc3ccccc3)cc2)cc1 +CCNC(=O)C1OC(n2cnc3c(Nc4ccc(OCC(=O)Nc5ccc(C(C)(C)C)cc5)cc4)ncnc32)C(O)C1O +CCn1cc(C2(c3nnc(NC)o3)NC(c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 +O=C1NC(=O)C(c2cn(CCCO)c3ccccc23)=C1Nc1ccccc1 +CC1CN(C2CCC(CC3CC3)(C(=O)NCc3cc(F)cc(C(F)(F)F)c3)C2)CCC12C=Cc1ccccc12 +CN(CCCCc1cn(-c2ccc(F)cc2)c2ccccc12)Cc1ccccc1 +Cc1sc2nc(-c3sc(NC(=O)c4ccccc4)nc3-c3ccccc3)nc(N)c2c1C +Cn1cccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCOCC6)ccn45)cccc32)c1=O +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1NCC(F)(F)C(C)(C)O +N=C1Sc2cc(-c3ccc4ncccc4c3)ccc2C2=NCCCN12 +O=C(c1cccc(C#Cc2ccccc2)c1)N1CCN(c2cnccn2)CC1 +N#Cc1ccc(COc2ccc3c(c2)cc2n3CCC2CC(=O)O)cc1C(F)(F)F +COc1ccc(N2Cc3cccc(C)c3C2=O)cc1OCCN1CCC(C)CC1 +COc1cccc(-c2cccc3c2Cc2c-3[nH]c(=O)c3nccn23)c1 +Cc1cccc(S(=O)(=O)Nc2cccc(C(c3c(O)c4c(oc3=O)CCCCCC4)C3CC3)c2)c1 +OC1CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2C(c2ccccc2)c2ccccn2)c1 +CCCCNC(=O)C(=O)NCCCCC=CCCCCCCc1noc(=S)[nH]1 +Cc1ccc2c(OCCN3CCN(Cc4ccc(C)c([N+](=O)[O-])c4)CC3)cccc2n1 +Cc1ccc2c(c1)c(Sc1ccc(S(C)(=O)=O)cc1)c(C)n2CC(=O)O +CCN1CC=C(c2ccccc2)C(C(=O)OCC(c2ccccc2)c2ccccc2)C1 +CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccccc3)nc2N1c1ccccc1 +N#Cc1cc(C(=O)NN=Cc2ccc(N(C(=O)C3CCCC3)C(=O)C3CCCC3)c3ccccc23)ccc1O +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(C(=O)OC2CCCC2)CC1 +O=[N+]([O-])c1ccc(N2CCNCC2)cc1NCc1ccccc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)C)n1)c1ccc(C(F)(F)F)cc1F +CC1CN(c2sc(C(F)(F)F)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)CN1C(=O)C(F)(F)c2ccccc21 +CCCCCCCCCC1=C(O)C(=O)C(Cc2ccccc2)=C(O)C1=O +CCCN(CCC1CCC(NC(=O)C=Cc2ccccc2Cl)CC1)C1CCc2nc(N)sc2C1 +O=C(O)c1ccc2[nH]c(-c3ccc(Oc4ccc(Cl)cc4)cc3)nc2c1 +COc1ccccc1N1CCN(CCCCC2CCCN2C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +CC(c1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1)N1CCCCC1 +COc1ncc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)cn1 +Cc1cc2c(cc1C)C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 +CCN(CC)CCNc1nc(NCCN(CC)CC)nc(Nc2ccc(S(N)(=O)=O)cc2)n1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(N)CCCc4cc(C(=O)O)ccc43)s2)c1 +O=C(O)CCN1CCC(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +O=C(O)CC(NC(=O)C1CCN(C(=O)c2cccc(NC3=CCC(O)CN3)c2)CC1)c1cnc2ccccc2c1 +COc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)ccc1-c1cc2ccccc2s1 +O=C(O)c1cccc(Oc2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)c1 +COc1cc(C2c3cc(O)c(O)cc3C=C(C=O)C2CO)ccc1O +CCCCCCCCCCCCn1nnc(C(NC(=O)c2c(C(C)C)cccc2C(C)C)c2ccccc2)n1 +FC(F)(F)c1ccc(Nc2nc(N3CCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1Cl +Cc1cc(COc2ccc(C(=O)NC3CN(S(C)(=O)=O)CCC3c3n[nH]c(=S)[nH]3)cc2)c2ccccc2n1 +CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]c(-c4cccc(C)c4)cc23)c1 +COC(=O)c1cc(CNc2ccc(S(=O)(=O)Nc3nnc(C)s3)cc2)cc(-c2ccc(OC)nc2)c1 +CCNC(=O)N1CCCC2Cc3cc(Cl)c(OC)cc3C21 +CCOC(=O)c1sc(NC(=O)CNCc2ccccn2)c(C(=O)OCC)c1C +CC(Nc1nccc(-c2cc(N3CCOCC3)nnc2-c2cccc(C(F)(F)F)c2)n1)c1ccccc1 +Cc1cccc(C)c1N1C(=O)C(=Cc2ccc(O)c(Cl)c2)SC1=NC(C)C +O=C(c1ccccc1F)N1CCc2oc(-c3ccc(F)cn3)nc2C1 +Cc1cc2c(-c3[nH]c4ccccc4c3N=O)c(O)[nH]c2cc1Br +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CCc2ncncc2C1 +CCC(CC)c1nn(CCCO)c2c1N=C(c1ccccc1)CNC2=O +NCC(C(=O)Nc1ccc2c(O)nccc2c1)c1ccccc1 +Cc1ccc2oc(-c3cc(Cc4ccccc4)ccc3O)cc(=O)c2c1 +COc1ccc(C2(C(N)=O)CC3CCC(C2)N3C(c2ccccc2Cl)c2ccccc2Cl)cc1 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCC2NCCC=C2c2ccc(F)cc2)cc1F +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CCNCC5)c4)ccn23)c1 +COc1ccc2nc(SSc3nc4ccc(OC)cc4s3)sc2c1 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+COc1cc(N2CCC(N3CCCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1 +CC(C(=O)OC1C[N+]2(CCc3ccccc3F)CCC1CC2)(c1cccs1)N1CCCCC1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5ccc(C(=O)O)cc5)C4)c3)nc2n(CCC)c1=O +Cc1cn(-c2ccc(-c3ccc4c(c3)CCC(C)N4C(=O)c3ccc(O)cc3O)nn2)cn1 +COc1cccc(OC)c1C=CC(=O)NC(C)c1nc2scc(C)c2c(=O)o1 +CNC(=O)COC1=C(C)CCC(Nc2ncc(F)c(Nc3ccc4c(c3)NC(=O)C(C)(C)O4)n2)=C1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1ccc(-c2ncc(C3(C(F)(F)F)CC3)[nH]2)nc1 +CC1(C)CCCC(NC(=O)C(S)Cc2ccccc2)C(=O)N1CC(=O)O +O=C(CN1CCC(N2CCCC2)CC1)Nc1cnc2c(c1)nc(O)c1ccccc12 +O=C(NCC(O)(c1ccc(F)cc1)C(F)(F)F)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CC(CCC(=O)Nc1cccc(S(N)(=O)=O)c1)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C +NC(=O)c1ccc(C2(C(N)=O)CC3CCC(C2)N3C(c2ccccc2Cl)c2ccccc2Cl)nc1 +O=c1ccn(COCCCS(=O)(=O)NC(c2cccc(OCC3CC3)c2)C2CC2)c(=O)[nH]1 +Cn1cncc1C(OCc1ccc(C#N)cc1)c1ccc(C#N)c(-c2ccccc2C(=O)O)c1 +COc1ccc(C(=O)Nc2ccc(-c3ccc(OC4CCN(C)CC4)cc3)cc2)cc1-c1cccc([N+](=O)[O-])c1 +CC(C)c1nnc2ccc(-c3ocnc3-c3cc(Cl)ccc3F)cn12 +Cn1c(=O)c2[nH]c(-c3ccc(OCCN4CCCC4)cc3)nc2n(C)c1=O +Nc1ncccc1-c1nc2ccc(-c3cccc(NC(=O)C4CC4)c3)nc2n1-c1ccc(C2(N)CCC2)cc1 +O=C(NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1)c1c(F)cccc1F +Nc1ncnc2c1C(=O)N(c1ccc(C3CCC(CC(=O)N4CC(O)C4)CC3)cc1)CCO2 +COC1CCN(c2nccc(Nc3cc4[nH]c(-c5cn[nH]c5)cc4cn3)n2)CC1 +Cn1c(COP(=O)(NCCBr)NCCBr)cnc1[N+](=O)[O-] +O=C(CNC(=O)c1ccncc1)NC(c1ccccc1)c1ccc(Cl)cc1 +CN(CCBr)P(=O)(OCC1OC(C2C=C(F)C(=O)NC2=O)CC1O)On1nnc2ccccc21 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5ccnn5C)cc4F)nccc3c2Cl)CS1(=O)=O +COc1ccc2[nH]cc(CCNC(=O)CCc3cc[n+](Cc4ccc(F)cc4)cc3)c2c1 +NC(=O)C12CC3CC(C1)C(NC(=O)c1cc(NS(=O)(=O)c4cccc(Cl)c4)ccc1Cl)C(C3)C2 +CCc1cc(NCc2cc3c(nc2OC)CCCC3)c(O)nc1C +NC(CC(=O)N1CCn2nncc2C1)Cc1cc(F)c(F)cc1F +CCCOc1ccc(S(=O)(=O)N2CC(N3CCCCC3)CC2C(=O)NO)cc1 +COc1ccc(-c2cc(CCC(C)(C(=O)NO)S(C)(=O)=O)on2)c(F)c1 +CCN1C(=O)CCC1C(=O)NCc1ccc(F)c(F)c1Cl +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1nnn(CC(C)C)c1C(=O)O +CN1CCN(c2cccc(N(CC3CC3)S(=O)(=O)c3ccc4ccccc4c3)c2)CC1 +COc1ccc(Cn2ccc3cccc(C=CC(=O)NS(=O)(=O)c4cccs4)c32)cc1 +O=C(O)c1cnn(-c2nc(NC34CCC(CC3)C4)c3ncn(C4OC(CO)C(O)C4O)c3n2)c1 +O=C(O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O +O=C(O)CCNC(=O)c1ccc(CC(CC2CC2)C(=O)c2cc3cc(Cl)ccc3n2-c2cccc(C(F)(F)F)c2)cc1 +Fc1cnc(-c2cc(-c3cnnc(-c4c(F)cncc4F)c3)ccc2F)c(F)c1 +CS(=O)(=O)c1ccc(-n2nncc2-c2ccccc2)cc1 +CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2CCc2ccccc2)n1Cc1ccc(C(=O)OC)cc1 +Cc1nn(C)cc1-c1nc(C(=O)Nc2cnn(C)c2N2CCC(N)C(F)CC2)c(N)s1 +COn1c(NC(C)c2ccc(C(F)(F)F)cc2)nc2c(c1=O)CN(C(=O)c1ccc3c(c1)OCCO3)CC2 +CCC(NNC(=O)c1ccccc1O)=C1C(=O)NC(=O)N(C2CCCCC2)C1=O +CC(Oc1ccc(Cl)c2ccccc12)C(=O)Nc1ccc2oc(-c3ccncc3)nc2c1 +COC(=O)c1[nH]c2cc(OC)ccc2c1C(=O)c1cc(OC)c(OC)c(OC)c1 +COc1ccc(-c2c(C(=O)O)n(Cc3ccc4c(c3)OCO4)c3cc(OC)c(OC)cc23)cc1OC +CNc1ccc(-c2cn3c(n2)sc2cc(Br)ccc23)cc1 +Cc1c(C(=O)c2ccccc2I)c2ccccc2n1CC1CCCCN1C +Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3CC(=O)N(C)C3=O)cc12 +Cc1ccc(S(=O)(=O)NC2CCC(N3CCN(c4ccccc4OC(C)C)CC3)CC2)cc1Cl +CCCCCCCC1=C(Br)c2nc3ccccn3c2C(=O)C1=O 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+COc1ncccc1-c1cccnc1Oc1ccc(Nc2nc3ccccc3s2)cc1 +Cc1n[nH]c(O)c1C(c1ccc(-c2ccccc2C(=O)O)o1)c1c(C)n[nH]c1O +CN(C)C1CC(c2ccc(Cl)c(Cl)c2)c2ccccc21 +Nc1nc(C#CC2(O)CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +NS(=O)(=O)c1ccc(NC(=S)NN=C2C(=O)Nc3c(Cl)cccc32)cc1 +Cc1cc(C)c(S(=O)(=O)NC(C)Cc2c[nH]c3ccccc23)c(C)c1 +CNc1nn2c3c(cnc2c1S(=O)(=O)c1ccccc1)CCC3 +CC(C)CC1C(=O)NC(C(=O)c2ccccc2)Cc2ccc(cc2)OCCCCCC1C(=O)NO +O=C(O)c1ccc2c(c1)nc(C(=O)NC1CCN(C3CC3)CC1)n2Cc1cc(-c2ccc(Cl)s2)on1 +CNC(=O)c1cc(NC(C)=O)ccc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +Cc1nc(NCc2ccc(F)cc2Cl)nc(-n2ccnc2C)c1[N+](=O)[O-] +NC1CCN(Cc2ccn3ncnc(Nc4ccc(OCc5ccccn5)c(Cl)c4)c23)CC1 +Cc1ccc(Nc2cc(Oc3c(C)cc(C)cc3C)n3ncnc3n2)cc1 +CC(O)c1ccc2[nH]c(-c3nc(C(F)(F)F)sc3N3CCN(C(=O)Cn4cnc5cccnc54)C(C)C3)nc2c1 +Brc1cc2c(cc1C1Nc3ccccc3C3C=CCC31)OCO2 +CC(=O)c1ccc(-c2nc3ccc(C(=O)N(CCC(C)C)CCC(C)C)cc3n2CCCN2CCCCC2)cc1 +CSCCC(NC(=O)c1cccc(C(=O)NC(CCSC)C(=O)N2CCCC2)c1)C(=O)N1CCCC1 +NS(=O)(=O)c1ccc(C2c3ccc(O)cc3CCN2S(N)(=O)=O)cc1 +O=C1NC(=O)C(=Cc2ccc(OCCOC3CCCCC3)cc2Cl)S1 +COC1=CC(=O)c2c(COc3ccc([N+](=O)[O-])cc3F)c(C)n(C)c2C1=O +Oc1ccc(C2Sc3cc(O)c(F)cc3OC2c2ccc(OCCN3CCCCC3)cc2)cc1 +CCc1nsc(N2CCN(C(=O)C3CNC(C(=O)N4CCCC4)C3)CC2)n1 +O=C(Nc1ccc2c(c1)N(S(=O)(=O)c1ccc(F)cc1)CCC2)c1c(F)cccc1Cl +N#Cc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)ccc1-c1nc(C2CCC3CCC(=O)N3C2)n2ccnc(N)c12 +CCOC(=O)C1C2CCC(CC1OC(c1ccc(F)cc1)c1ccc(F)cc1)N2 +CC(C)Oc1cccc(C2CC2c2ccc3cc(C(=N)N)ccc3c2)c1 +CC(=O)N1CCN(C(=O)C=Cc2ccc(Sc3ccc4c(ccn4CC(=O)O)c3)c(Cl)c2)CC1 +Cc1cccc(-c2[nH]c(CNc3cccc(CN4CCOCC4)c3F)nc2-c2ccc3ncnn3c2)n1 +O=C(Nc1ccccc1N1CCC(CO)CC1)c1ccc([N+](=O)[O-])o1 +Cc1c(N(CCCCC(F)(F)F)S(=O)(=O)c2ccccc2)sc2ccccc12 +COc1cc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cnc1OC(C)C +CCN(Cc1c(C(F)(F)F)nc2n(-c3c(C)cc(C)cc3C)c(Cl)cn12)CC1CC1 +COc1ccccc1C(=O)NC(=O)Nc1ccc(-c2ccccc2)c(C(F)(F)F)c1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NC1CCCC(F)(F)C1O +Cc1ccc(NC(=S)NC(=O)c2cn(-c3ccccc3)nc2-c2ccccc2)cc1 +CCCCc1cc(NC(CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(C(C)(C)C)c2)n1 +CC(O)C(=O)NC(C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)N1CCCN(C(=O)C2(c3ccccc3)CC2)CC1 +O=C(O)C(C1CCN(C(=O)C=Cc2cc(F)c(F)c(F)c2)CC1)N1CCC(c2c[nH]c3ccc(O)cc23)CC1 +CP1(=O)OCCC2(CCCC3(S(=O)(=O)c4ccc(Cl)cc4)c4c(F)ccc(F)c4OCC23)CO1 +CCCCCCCCCCn1nnnc1NC(=O)Nc1c(C(C)C)cccc1C(C)C +COc1ccc(-c2c(C(F)(F)F)nn3c(=O)cc(-c4cc(F)c(Cl)nc4Cl)[nH]c23)cc1OC +O=C(Nc1cccc(Nc2cc3c(cc2Cl)C(=O)NC3=O)c1)c1cccc(OC(F)(F)F)c1 +COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OCC1CN2CCOCC2CO1 +O=C(O)CCc1ccc(C(=O)CNC(=O)c2cc3c(s2)CCNC3)cc1 +CC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(-c5ccsc5)cc34)cn2)CC1 +N#Cc1cc(Cl)c(-c2nc3ccnc(Nc4cc(N)ncn4)c3[nH]2)c(Cl)c1 +CCCCN(CCCC)c1ccc2c(c1)Cc1cc(NC(N)=S)ccc1-2 +CC(=O)N(C)CCn1ccc2cc(C(=O)N3CCC(N4C(=O)OCc5ccccc54)CC3)ccc21 +Cc1ccc(-n2nccn2)c(C(=O)N2CCC3CN(c4nc(C)cc(C)n4)C3C2)c1 +O=C(c1ccc(F)c(F)c1Cl)N1CCN(c2ccc(F)cc2Cl)C(=O)C1 +COc1cc(OCc2cccc(-c3ccc([N+](=O)[O-])nc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(Nc1cnn(C2CCOCC2)c1)c1ccc2cc3n(c2c1)CCCNC3=O 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+OC12CCCCC13CCN(CC1CCC1)C2Cc1ccc(OCCc2ccccc2)cc13 +O=C1OC2(CCN(C(=O)Nc3ncc(-c4cccc(C(F)(F)F)c4)cn3)CC2)c2ccccc21 +CN(C)CCCNC(=O)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCCC(=O)O)no2)cc1C#N +COC(=O)C(c1ccc(F)cc1)N1C(=O)c2cc(Cl)ccc2NC(=S)C1c1ccc(Cl)cc1 +C[S+]([O-])c1ncc(C(=O)Nc2ccc(CCN3CCOCC3)cc2C2=CCCCC2)[nH]1 +Cc1c(-c2ccccc2)n(Cc2ccc(OCCN3CCCCC3)cc2)c2ccc(O)cc12 +CC(C)n1c2nc(-c3ccccc3)nc(=O)c-2[n+]([O-])c2ccccc21 +CN(C)c1ccc(-c2nc3ccc(OCCF)cc3s2)cn1 +CCNC(=O)C1OC(n2cnc3c(Nc4ccc(OCC(=O)NC5CCCCC5)cc4)nc(Cl)nc32)C(O)C1O +CN1OC2(N=C1N)c1cc(-c3cc(Cl)cc(Cl)c3)ccc1CC21CCc2ccccc2CC1 +CNC(=O)c1cccc2c(Nc3cc(N)cc(CO)c3)c3cccc(C)c3nc12 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cn5cc6cccc(F)c6n5)C4)cc23)ccn1 +O=C(O)c1ccc2c(c1)C(=NCc1cccnc1)c1ccccc1CO2 +CNC(=O)C1CC(N)C(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)O1 +CCCN1CCc2cccc3c2C1Cc1cccc(OC(=O)NC(C)(C)C)c1-3 +CNCC1CCC2C(c3cccs3)Nc3ccc(C(C)(C)C)cc3C2O1 +NC(CC(=O)N1CCn2c(nnc2-c2ccncc2)C1)Cc1cc(F)ccc1F +O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c2ccccc12 +N#CC1(NC(=O)C2CC(S(=O)(=O)c3ccccc3)CC2C(=O)N2CCOCC2)CCC1 +COc1cc2c(cc1OCCCF)CCN1CC(CC(C)C)C(O)CC21 +O=C1NC(=O)C2(N1)OC(COP(=O)(O)O)C(O)C2O +CC1(C)C2CC(CC=CCCCC(=O)O)C(NC(=O)c3ccsc3)C1C2 +C=CCn1ncc2c(NCCC)nc(N3CCC(NCC4c5ccccc5CCc5cc(OC)ccc54)CC3)nc21 +CNCC1C2CCC(C2)C1c1ccc2cc(OC)ccc2c1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1cc(C(F)(F)F)ccc1F +CCn1nc(-c2ccc(C(C)N3CCC(CC(C)(C)O)(c4ccccc4)OC3=O)cc2)ccc1=O +CCCCC1(CCCC)CS(=O)(=O)c2cc(CNC(CC(=O)O)CC(=O)O)c(OC)cc2C(c2ccccc2)N1 +CCOC(=O)C1Nc2cc(Cl)cc(Cl)c2S(=O)(=O)N1Cc1cccc(C)c1 +Cc1nc(C#Cc2cnc(N3CCCC(CO)C3)nc2)cs1 +Cc1ccc2nc(N3CC=CC3)nc(NCc3ccc(NC(=O)C4CCN(Cc5ccccc5)CC4)cc3)c2c1 +Cc1[nH]c(C=C2C(=O)Nc3ccc(C(=O)O)cc32)c(C)c1CCC(=O)O +CCc1ncnc(-c2cc(F)c(C(=O)N3CCN(CC)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1)c1c(Cl)cncc1Cl +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(-n5cccn5)cc4)nc23)N1 +COc1c(-c2ccccc2)[nH]c2c(N3CCCCC3)nc(C)nc12 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+CC(C)(C)c1ccc(-c2nc3c(N4CCN(Cc5ccc6ncccc6c5)CC4)cccc3[nH]2)cc1 +CC(C)(C)OC(=O)NN(CC1CCCCC1)c1nc(C#N)ncc1Br +CC(=O)N1CCC(c2cc(C#N)cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)c2Cl)CC1 +Cc1cc(C2CCN(C(=O)NC3CCCCC3)CC2)n(-c2ccc(S(N)(=O)=O)cc2)n1 +CCOC(=O)NC(CC(=O)N1CCN(C(C#N)c2cccnc2C)CC1)c1ccccc1 +CC(C)(C)CC(N)C(=O)N1CCN(CCCOc2ccc(C(=O)C3CC3)cc2)CC1 +Cc1cc(C)c(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCC1CCCO1 +N#Cc1ccc(-c2cc(Cl)ccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)nc1 +CCc1ncc(Cc2ccc3cccc(NC(C)=O)c3n2)c2cc(OC)c(OC)cc12 +CCC(Cc1ccc(O)cc1)NCC(O)c1cc(O)cc(O)c1 +Cc1cc(C)c(C)c(S(=O)(=O)N2CCc3ccccc32)c1C +COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccccc1 +O=C(c1ccc(Cl)c(Cl)c1)N1CCC(CNCc2cccc(-c3cnco3)n2)CC1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(Cc4cc(C)no4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(=O)c3ccncc3)oc12 +O=C(O)CCCSCCN1C(=O)CCC1C=CC(O)Cc1cccc(OCc2ccncc2)c1 +Cc1nc(NCCCCNc2ccnc3cc(Cl)ccc23)nc(-c2ccccc2)c1C(=O)OC(C)C +O=C(Cc1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1)NCc1ccccc1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(c1ccc(Cl)c(F)c1)C1CCCN1 +COc1ccc2c(c1)c(CC(=O)NCCCCCCO)c(C)n2C(=O)c1ccc(Cl)cc1 +CCCNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc21 +CN(c1ccc(Cl)cc1)c1ccc(C(=O)c2ccc(C(=O)C(C)(C)C)c(C(=O)O)c2)nc1 +Cc1cc(N)nc(CCc2cc(F)cc(CCCN(C)C)c2)c1 +Fc1ccc(N(CCCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C2CCNCC2)cc1 +CCC(O)(c1ncc(-c2cc(C)cc(Nc3cc(C(F)(F)F)ccn3)n2)s1)C1CCC(C(=O)O)CC1 +COc1cccc(F)c1CN1CC(C)CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nsnc5c4)c3c2)C1 +N#CC1CCN(c2nccnc2C2CN(c3ncc4ccccc4n3)C2)CC1 +O=S1(=O)N(Cc2ccc(CO)cc2)C(COc2ccccc2)C(O)C(O)C(COc2ccccc2)N1Cc1ccc(CO)cc1 +O=C(Nc1ccc(F)c(-c2nc3ccccc3o2)c1)c1cnccc1Cl +N=C(N)c1ccc(CC(=O)CCC(=O)NC(CC(=O)O)C(=O)NC(Cc2ccccc2)C(=O)O)cc1 +CS(=O)(=O)c1ccc(N2C(=O)OC(=Cc3ccc(O)c(Br)c3)C2=O)cc1 +Cn1cc(-c2ccc3c(c2)[nH]c2c(C(N)=O)cnc(NC(C4CC4)C(F)(F)F)c23)cn1 +CC1CCCN1CCc1ccc(-c2ccc(CC(=O)O)cc2)cc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cnn(-c2ccc(OC(F)(F)F)cc2)n1 +O=C(Nc1ccc(-c2ccc3cn[nH]c3c2)cc1)Nc1cccc(F)c1 +COC(=O)c1c(Cl)cccc1-c1ccc(C(C)NC(=O)C2(NC(=O)c3ccno3)COC2)c(F)c1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)NCc2ccccn2)c1=O)C(=O)C(F)(F)F +O=C(Nc1ccc(F)cn1)c1cc(Oc2cncc(F)c2)cn2cnnc12 +NS(=O)(=O)c1ccc(CCNC(=O)CNCCNCC(=O)O)cc1 +Cc1cc(N)nc(C)c1CNC(=O)Cc1c(Cl)ccc(NCC(F)(F)c2ccccc2)c1F +CN(c1ncnc2[nH]ccc12)C1CCC(CS(=O)(=O)N2CCC(NC(=O)OC(C)(C)C)C2)CC1 +CN(Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)COc1ccc(Cl)cc1)CC2)c1ccc(C(F)(F)F)cc1 +CC(C)CC(C(=O)NO)N1CCC(N)(c2ccc(OCc3cc(C(F)(F)F)nc4ccccc34)cc2)C1=O +Cc1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)c(Cl)s1 +CCCCC(C(=O)N1CCCC1C(=O)Nc1ccc(Cl)c(Cl)c1)C(F)C(=O)NO +N=C(N)c1cccc(NC(=O)Nc2cccc(S(=O)(=O)NCc3ccc(S(N)(=O)=O)cc3)c2)c1 +CC(C)Oc1cc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)cc(OC(C)C)c1 +NC1(c2ccc(-c3ncc4cccnc4c3-c3ccccc3)cc2)CCC1 +CC(c1ccc(Br)cc1)n1c(CC(C)(C)C(=O)O)nc2cc(OCc3ccc4ccccc4n3)ccc21 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1 +COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1F +Brc1ccc2c(c1)ncc1nc(-c3ccccc3Br)[nH]c12 +O=C1NCN(c2ccccc2)C12CCN(CCCOc1ccc(F)cc1)CC2 +N#Cc1cnc2c(Cl)cc(NCc3c[nH]nn3)cc2c1Nc1ccc(F)c(Cl)c1 +COC1CCC(CC(=O)NC2CCC(CCN3CCN(c4cccc5c4OCO5)CC3)CC2)C1 +O=C(c1cc(C2CC2)c(O)cc1O)N1Cc2ccccc2C1 +Cc1cc(C=NNc2nc(N)ncc2[N+](=O)[O-])c(C)n1-c1ccccc1F +Cn1nccc1-c1ccc(I)cc1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1C#N +CC(Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Br)c2c(=O)n1-c1cncc(F)c1 +O=C(O)c1cc2c(s1)-c1ccc(Cl)c(Cl)c1CC2 +CC(=O)Nc1cc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)ccn1 +CC(Nc1nc(N)nc(N2CCC(CC(N)C(=O)O)CC2)n1)c1ccc2ccccc2c1 +CCOc1ccc(-c2nc(C#N)nc3c2ccn3CC(=O)N2CCN(C)CC2)cc1C(F)(F)F +COc1cccc(N2C(=O)N(Cc3ccccc3F)C3(CCN(Cc4ccc(-c5ccncc5)cc4)CC3)C2=O)c1 +CCN(CC)CC(c1ccccc1Cl)N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)CC2NCCc3ccccc32)CC1 +CC(c1ccccc1)N(CC#Cc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21)C(=O)C(C)(C)C +O=C(Nc1ccc(OCCc2ccsc2)cc1C(=O)O)c1ccc(Cl)cc1Cl +CCCc1cc(=O)n2nc(NCc3ccc(Cl)cc3OC)c(C#N)c2[nH]1 +CCN(CC)C(=O)C1Sc2cc(OCCF)ccc2-c2c1c1ccccc1n2C +CCOC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +CCc1nc(N)nc(N)c1C#CC(C)c1cc(OC)cc(-c2cccc3cnccc23)c1 +O=C1NC(=O)C(Cc2ccc(N3CCC(NCC(O)c4ccc(O)c(NS(=O)(=O)c5ccccc5)c4)CC3)cc2)S1 +COc1nc(Nc2ccc(C#N)cc2)nc(Nc2c(Br)cc(C)cc2Br)n1 +O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(c1ccc(F)cc1)c1ccccc1[S+]2[O-] +CCOC(=O)CSC1=C(C#N)C(c2ccc(C)o2)CC(=O)N1 +Cc1cc(CN(C)C)ccc1C(=O)Cn1ncc(OCc2ccc(Cl)cn2)cc1=O +Cc1nc(C(F)(F)F)c(-c2cc(C(=O)N3CC(F)(c4ccc(C#N)cc4)C3)c(C)cc2C)[nH]1 +Cc1ccc2c(-c3nnc(SCCCN4CCc5cc6c(cc5CC4)OCC(=O)N6)n3C)cccc2n1 +CC(C)=CCOc1cc(Oc2ccc(S(=O)(=O)N3CC4CCC(C3)O4)cc2)cc(C(=O)Nc2cc(C)n(C)n2)c1 +CS(=O)(=O)Oc1ccc2c(c1)OS(=O)(=O)C=C2 +Fc1ccc(-c2[nH]c(SCCc3ccccc3)nc2-c2ccncc2)cc1 +COc1ccccc1-c1ccc(C(N)=O)c2[nH]c3cc(C(=O)N4CCN(C)CC4)ccc3c12 +COc1ccc2c3c4c(c5c(ccc6ccn(C)c65)c3n(CCCN3CCN(C)CC3)c2c1)C(=O)NC4=O +CC(C)c1n[nH]cc1-c1ccnc(Nc2ccc(N3CCNCC3)cn2)n1 +Cc1cc2c(OCC(O)CN3CCC(c4cccc5ccsc45)CC3C)cccc2[nH]1 +O=C(CCc1ccc(C(=O)NCC(NS(=O)(=O)c2cccc3cccnc23)C(=O)O)s1)NC1=NCCCN1 +Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc(OC(F)(F)F)cc1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OCc3ccccc3)cc2n1Cc1ccccc1 +C=CCN1CCN(C(c2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)CC1 +COCCOc1c(OC)cc(Cc2cnc(N)nc2N)cc1OC +CCn1c(-c2nonc2N)nc2cncc(CN3CCC(N)CC3)c21 +CCC1C(C)C(Nc2ccccc2)c2ccccc2N1C(=O)c1ccc(Br)cc1 +COc1ccc(Nc2nc3ccccc3cc2-c2nc(C)nc(N)n2)cn1 +N#Cc1cccc(CC2(c3cccc(OC(F)(F)F)c3)CN(CC(O)C(F)(F)F)c3ccccc32)c1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc(Cl)ccc1Cl)C(F)(F)F +Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccc(F)cc3)C2=O)cn1 +C1=C(c2cccnc2Oc2ccc(Nc3nc4ccccc4s3)cc2)CCNC1 +Cc1cc(C#N)cc(C)c1Oc1cc(Cl)nc(NC2CCN(Cc3ccncc3)CC2)c1 +Cc1noc(C)c1-c1ccc(F)c(COc2ccc(CCC(=O)O)c(F)c2)c1 +CCN(CC)CCOc1ccc(Cn2c3ccccc3c3sc4cc(O)ccc4c32)cc1 +CCCc1nc2ccc(C(=O)NC(CC)c3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(C=Cc1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1)NO +Nc1ccc(S(=O)(=O)c2cnc(-c3ccc(S(N)(=O)=O)cc3Cl)s2)cn1 +COc1cccc(Nc2c(C(N)=O)cnc3ccc(S(=O)(=O)c4ccc(-c5ccoc5)cc4)cc23)c1 +Cc1cccc(C#CC2(O)CC3CCC(C2)N3C(=O)N2CCC2)c1 +COc1cnc(C(=O)Nc2cc(F)c(F)c(C3(CF)N=C(N)OC4CC43)c2)cn1 +CCC(CO)Nc1nc(-c2ccc(C(C)(C)O)nc2)cc2ncn(C)c(=O)c12 +Cc1cc(C)cc(C(=O)C2(NC(=O)c3ccc4c(c3C)CCCO4)CCCCC2)c1 +CCCS(=O)(=O)c1ccnc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)c1 +O=C(NO)c1ccc(-c2ccc(CNCc3ccc4c(c3)OCO4)cn2)s1 +COC12C(COC(N)=O)C3=C(C(=O)C(CSc4nccn4C)=C(N)C3=O)N1CC1NC12 +CC(C)c1ccccc1N1CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)CC1=O +COc1cc(C=CC(=O)c2cc(OC)c(OC)c(OC)c2)ccc1B(O)O +Cn1c(-c2ccc(N3CCNCC3)cc2)c(-c2ccc(CO)cc2)c2c(Cl)ccnc21 +COc1ccc2[nH]c3c(c2c1)C1(c2cccc(O)c2)CCN(C)C(C3)C1 +CC(CCC(=O)NCCC(=O)Nc1nnc(S(N)(=O)=O)s1)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C +CNC(=O)c1nn(C)cc1NC(=O)c1nc(C(C)C)ncc1Nc1cncnc1 +CN(C)c1ccc(-c2nc3ccc(NC(=O)c4ccccc4)cc3o2)cc1 +CCCNC(=O)Nc1cccc(-c2ccc(CC(NS(=O)(=O)c3ccc(OC)c(OC)c3)C(=O)O)cc2)c1 +O=C(O)c1ccc(C(=O)Nc2cc(C3CC3)[nH]n2)cc1 +CC(=NOCCO)c1ccc2nnc(Cc3cc4cccnc4cc3F)n2n1 +CC(NC(=O)c1cnco1)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 +COc1cnc(-c2ccc(NC(=O)Nc3cccc(C(N)=O)c3)cc2)nc1N1CCOCC1 +Cc1ccc2oc3c(=O)[nH]c(-c4ccccc4Cl)nc3c2c1 +CC1COc2ccc(Br)cc2C(C)N1C(=O)c1ccc(Cl)cc1 +CCCCc1nc2ccn(Cc3ccccc3Cl)c(=O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCOCCn1c(=O)c(NCCCO)nc2cnc(-c3ccc(OC)nc3)cc21 +CC(C)C(NC(=O)c1ccc(Cl)cc1)C(=O)N1CCC(N)(c2ccc(Cl)cc2)C(C)(C)C1 +Cc1[nH]nc(N)c1-c1nc2c(F)cc(S(N)(=O)=O)cc2s1 +Cc1c(CNC2CCC(F)C2)nn(CCC#N)c1-c1cc(F)cc(F)c1 +COc1ccc(Cc2nc3c(o2)CCc2cc(-c4ccnc(C)c4)ccc2C3=O)cc1 +CC(C)(C)C(=O)OCC1(CO)CC(=Cc2ccc(F)c(Cl)c2)C(=O)O1 +CNC(=O)Oc1ccc2c(c1)C1(C)CCN(C)OC1N2C +c1cc(C2=NCCN2)ccc1NCCCCCNc1ccc(C2=NCCN2)cc1 +CCOc1cc(-c2cccc(F)c2)cnc1Nc1cccc(C)n1 +CNCc1ccc(-c2cncc(CCc3cc(C)cc(N)n3)c2)cc1 +Cc1c(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)ccc2c1COC2=O +Cc1cc(Cl)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CC1(C)CC(N)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3ccc(O)cc3F)n2)C1 +O=C(NCc1ccc(Cl)cc1)c1cn2c(C(O)CO)cc3cc(CN4CCOCC4)cc(c1=O)c32 +CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2c(O)ccc[n+]2[O-])cc1 +Cc1cccc(-c2cc(Nc3nn(C)cc3C(F)(F)F)nc3[nH]cc(C#N)c23)n1 +COc1ccc(C2CN(C)Cc3cc(OCCCN4CCC(F)(F)C4)ccc32)cc1 +CC1(C(=O)O)CCc2ccc(OCCCOc3ccc(C4CCC5(CC4)CC5)cc3Cl)cc2O1 +COc1cccc(C(=O)NCCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1 +O=C(Nc1ccc(Cl)cc1)C1CN(Cc2ccncc2)CC1C(=O)Nc1ccc(-n2ccccc2=O)cc1F +COc1cc2ncnc(Nc3ccccc3F)c2cc1OCCCCC(=O)NO +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(C4CCN(C(=O)OC(C)(C)C)C4)C3)cc12 +COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)cc1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccccc1-c1ccccc1F +O=S(=O)(Nc1cc(-c2ccc3nccc(N4CCN(Cc5ccncc5)CC4)c3c2)cnc1Cl)c1ccc(F)cc1 +CC(C)Cc1ccc(CN2CCCC(NC(=O)c3cnc4ccccn4c3=O)C2)cc1 +CCc1cc(OCC2=C(c3cccc(-n4ncc(C(=O)O)c4C)n3)CCCC2C)ccc1C1CCN(C(=O)C2CC2)CC1 +O=C1NC(=S)SC1=Cc1csc(-c2ccc(OC(F)(F)F)cc2)n1 +CCC(CC)c1nnc(-c2nc(-c3ccc(Cl)cc3Cl)n(-c3ccc(Cl)cc3)c2C)o1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CC(=O)Nc5ccccc54)ncc23)ccn1 +Cc1nc2ccc(CNc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 +COC(=O)c1ccc(CCCCN=C(N)NC(=O)c2nc(Cl)c(N)nc2N)cc1 +Cc1cc(C)cc(C(=O)Nc2ccc(Cl)c(C(=O)Nc3cncs3)c2)c1 +COc1ccc(CC(NC(=O)C(NC(=O)C(Cc2ccc(OC)cc2)NC(=O)c2ccc(Cl)cn2)C(C)C)B(O)O)cc1 +C=C(c1ccccc1OCC(O)CNC(C)(C)C)n1cnc2ccccc21 +CC1CC(=O)N(C2CCN(C3CCCCCCC3)CC2)c2ccccc21 +Cc1cc(=O)n(-c2ccc(Br)cc2F)nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 +CC(=O)N1CCC2(CCC(Nc3nc(Nc4cnn(C)c4)ncc3Cl)CC2)CC1 +COC(=O)C1CCCCC1c1nc(C2CCCCN2C(=O)COc2ccccc2)no1 +COc1cc2ncnc(Nc3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c2cc1OC +CC(C)(C)c1cn(CC2CCCO2)c(=NC(=O)c2cc(C(F)(F)F)ccc2OCc2ccccc2)s1 +Cc1cc(-n2cnc3c(NCC4CCOCC4)cc(Oc4ccc(Cl)c(F)c4)cc32)ccc1C(=O)NC1CC1 +O=C(COc1ccc(C(=O)NO)cc1)Nc1ccc2ccnc(Nc3ccc4ccccc4c3)c2c1 +CC(=O)N1CCN(Cc2ccnc(Nc3ncc(C#N)s3)c2)CC1 +CN1C(=O)CC(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c3ncccc23)N(C)C1=O +CNCc1cc(-c2cccnc2F)n(S(=O)(=O)c2cccc(C#N)c2)c1 +O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2nc(-c3ccc(Cl)cc3)cs2)C2C=CC1C21CC1 +CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(Cc1ccccc1)NC(=O)C1CCCS(=O)(=O)C1 +Cc1ccc(-c2cccc(C3OC(CO)C(O)C(O)C3O)c2)cc1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C1CCCN1 +CCCCc1nc2[nH]cnc2c2nc(-c3ccc(OCC)cc3)nn12 +CCCC(CCC)(CNC(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 +[H]C(=NN1CC(=O)NC1=O)c1ccc(-c2ccc(N=[N+]=[N-])cc2)o1 +NC1CCCCC1Nc1cccc2nc(-c3c(NC4CCCNC4)nc(N4CCOCC4)[nH]c3=O)sc12 +N#Cc1cc(NCc2cc(F)c(F)cc2-c2ccc(C(=O)NCCC(=O)O)nc2)ccc1-c1ccc(Cl)cc1F +COc1cc(C(=O)OCCCN2CCCN(CCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2)cc(OC)c1OC +CCN(CC)C(=O)C1CCCc2c1c1c(OC)cccc1n2CCF +CC(C(N)=O)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +N#CCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN(C)C(=O)c2ccccc2)c1C +Cc1cc(C)c(Oc2ccc([N+](=O)[O-])c(NC3CCN(Cc4ccc(S(N)(=O)=O)cc4)CC3)c2)c(C)c1 +CCOC(=O)C=CC(=O)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +O=C(CSc1ccc(C(=O)Nc2ccc(F)cc2)cn1)OCc1ccc(Br)cc1 +CN(C)CC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 +COC1CN(c2nc(-c3cc(C)ccc3OCc3ccc4c(c3C)CCN(CC3CCOC3)C4)cs2)CCC1C(=O)O +CN(C)C1CCN(c2cc(NCC(C)(C)C)ncn2)C1 +COc1ccc(C=C2SC(=Nc3nsc4ccccc34)NC2=O)cc1 +CN(C)CCOc1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +CCC1(c2ccc(CSc3ccc(F)cc3)cc2)Oc2ccccc2-n2cccc2C1=O +Clc1ccc(N2CC3CC2CN3Cc2c[nH]c3ncccc23)cc1 +CC(C)n1c(Nc2cccnc2)nc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21 +CCCn1ncn(-c2ccc(N3CCN(c4ccc(OCC5COC(C)(c6ccc(Cl)cc6Cl)O5)cc4)CC3)cc2)c1=O +O=C(N1CCOCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 +CC1COC(c2cccc(OC(=O)NC3CCCCC3)c2)=N1 +O=C(O)c1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3cccc(B(O)O)c3)cc2)cc1 +CC(C)c1ccc(NC(=O)Oc2ccc3c(c2)C2(C)CCN(CCc4ccc(F)cc4)C2N3C)cc1 +O=C1NC(=O)c2cccc(NC(=O)c3ccc([N+](=O)[O-])cc3)c2C1=O +C#Cc1nc(NC)c2ncn(C3CC(OP(=O)(O)O)C4(COP(=O)(O)O)CC34)c2n1 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC2C(=O)Nc3ccc(Cl)cc3C2C1 +O=c1c(-c2ccc(F)cc2)c(-c2ccnc(Oc3ccccc3)n2)n2n1CC(N1CCCCC1)C2 +CCC(=O)N(c1ccccc1)C1CCN(CCc2ccc(N=C=S)cc2)CC1C +O=C(O)c1cccc(-c2cnc(C(=O)C3Cc4ccc(Oc5ccccc5)cc4C3)o2)n1 +CCc1nc2ccc(C3CCN(CC(=O)N4CCCC4)CC3)cn2c1N(C)c1nc(-c2ccc(F)cc2)cs1 +CS(=O)(=O)c1cccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)c1 +CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5ccc(Cl)c(Cl)c5)s4)c2C3)CC1 +Nc1ncc(Cc2ccc(OCc3ccccc3)cc2)c(N)n1 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+O=C(c1cccc(O)c1)c1ccc(-c2cccc(NS(=O)(=O)c3ccccc3[N+](=O)[O-])c2)s1 +O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(OC(F)(F)F)cc3)c(Cl)c2)cn1 +N#Cc1cc(S(=O)(=O)c2cccc(Cl)c2)cc2c3c(oc12)CCNC3 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(OC4CCC4)cc3)C2)cc1 +O=C(C1CC1c1ccccc1)N1CCC(N2CCCCC2)CC1 +Cc1cc(Oc2ncccc2Br)ccc1-c1c(C)n[nH]c(=O)c1C +CCc1c(C)c2c(c(O)c1CC=C(C)CCC(=O)O)C(=O)OC2 +O=c1cc(OCc2ccc(F)cn2)ccn1-c1ccc2c3c([nH]c2c1)CC1CCC3N1 +Cc1c(-c2ccccc2)oc2c(C(=O)NCCCN3CCN(c4ccccc4OCCCO[N+](=O)[O-])CC3)cccc2c1=O +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1cccc(N=[N+]=[N-])c1 +COc1ccccc1CC(=O)Nc1nc(N)nc(-c2ccco2)c1[N+](=O)[O-] +COc1ccc(C2C(c3ccccc3)C(=O)N2c2ccc(S(N)(=O)=O)cc2)c(OC)c1OC +Cc1nc2cccc(-c3cc(C(N)=O)n[nH]3)c2nc1NC(C)(C)C +CCc1cc2c(cc1Cn1c(C(=O)O)c(Cc3cccc(C(=O)O)c3)c(=O)c3cc(OCC(C)C)ccc31)OCO2 +CCN(CC)C(=O)C1Sc2cc(O)ccc2-c2c1c1ccccc1n2CCF +CCNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3sccc3n2)cc1 +Cc1cnc(Cl)nc1-c1ccc(N(Cc2cccc(OCCCCN3CCOCC3)c2)C(=O)c2ccc(O)cc2O)cc1 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+C#CCn1c(=O)c2c(-c3cc(C#N)cn3C)n(Cc3ccnc4ccc(Cl)cc34)nc2n(CC2CC2)c1=O +Cc1nsc(-c2ccc(N3CCN(c4cc(Cl)cc(Cl)c4)CC3)nn2)n1 +CCCC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1CC +CCc1nn(Cc2ccc(-c3nc4c(F)c(F)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4cccc(OC(F)(F)F)c4)nc23)N1 +CNCCCCNCCCCNCc1ccc(CNCCCCNCCCCNC)c2ccccc12 +NC(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O +CN(CCO)Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 +Cc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)NS(=O)(=O)C1CC1)n2Cc1cc(C#N)ccc1F +O=C(O)C1CCCN1C(=O)c1cccc(COc2ccc(-c3cc(F)c(F)c4c3OCC=C4)cc2)c1 +COc1cccc2c(CC3NC(=S)N(C)C3=O)c[nH]c12 +Cc1ccc(Oc2ccc(N(CC(O)C(=O)NO)S(=O)(=O)Cc3ccncc3)cc2)cc1 +CC12CCC3c4ccc(O)cc4CC(CCCCc4cn(CC5COc6ccccc6O5)nn4)C3C1CCC2O +Cc1c(C(C)c2c(F)cccc2F)nc(N2CCSCC2)[nH]c1=O +CC(Nc1ncnc(N)c1-c1ccc(N)nc1)c1nn2cccc2c(=O)n1-c1ccccc1 +COc1ccccc1COCCCOc1ccc(C2=C(C(=O)N(C)Cc3ccccc3)C3CN(C(C)=O)CC(C2)N3)cc1 +FC(F)(F)Oc1cccc(Nc2nc3cc(-c4nnn[nH]4)ccc3c3sccc23)c1 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+C#CCCCCCNC(=O)c1coc(C2C3CCC(O3)C2Cc2ccccc2CCC(=O)O)n1 +CC(C)NC(=O)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)CCc1ccccn1 +NC(N)=NCCCC(N)C(=O)CC(Cc1ccccc1)C(=O)O +CCC(C)C(NC(=O)C(S)C(N)CCS(=O)(=O)O)C(N)=O +CN(C)CCOc1ccc2[nH]c(C(=O)N3CC(CCl)c4ccc(N)cc43)cc2c1 +COCCCS(=O)(=O)c1ncccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +c1cc2nc(c1)CNCCCN(Cc1ccc(CN3CCCNCc4cccc(n4)CNCCC3)cc1)CCCNC2 +O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC(c2ccccc2)(c2nccn2Cc2ccccc2)CC1 +C=CCNc1nc(N2CCC(NCC3c4ccccc4COc4ccccc43)CC2)c2ncn(CC=C)c2n1 +CN(C)C(=O)c1ccc(NCc2cncn2Cc2ccc(-c3ccccc3)cc2)cc1-c1ccccc1 +O=C(OCc1ccccc1)C(CCCCn1cnc2c1NC=NCC2O)(Cc1ccccc1C(F)(F)F)C(=O)OCc1ccccc1 +CC(C)C1=C(CCNC(=O)C2CC2)c2c(ccc3c2CCO3)C1 +CCCCOc1ccc(-c2ccc(C(=O)O)cc2F)cc1CNC(=O)c1ccc(C(F)(F)F)cc1 +CCc1nn(Cc2ccc(NC(=O)OCc3ccccc3Cl)cc2)c(CC)c1CC(=O)O +COc1cc2c(cc1C)CC1C2CCCN1C(=O)c1ccc2nc[nH]c2c1 +CCC(NC(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(N2CCOCC2=O)cc1 +Cc1nc(COc2ccc3c(c2)C(O)C(Cc2cccnc2)CO3)ccc1[N+](=O)[O-] +Nc1cc(NC2=NCC(O)CN2)cc(C(=O)NCC(=O)NC(CC(=O)O)c2cc(Cl)cc(I)c2O)c1 +O=C(c1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CCN(Cc1ccncc1)Cc1cccc(-c2ccc(CCNCCc3ccc(O)c4[nH]c(=O)sc34)cc2)c1 +CC(C)(O)c1ccc(Nc2nc3ccc(C#N)cc3[nH]2)cc1 +COc1ccc(CCCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 +NC(=O)n1cc(NC(=O)N2CC(F)CC2CNS(=O)(=O)c2cccc(Br)c2)c2ccccc21 +Fc1cnc(N2CCN(CCCCc3ccc(F)c4ccccc34)CC2)nc1 +COC1Cc2sc(-c3ccccc3)cc2C2(CCN(Cc3ccco3)CC2)O1 +Nc1nccc(-c2cc3c([nH]2)CC(C2CC2)NC3=O)n1 +COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C +COc1ccc(-c2nc3cnc(NCc4ccc(F)c(Cl)c4)nc3n(CCNC(C)=O)c2=O)cc1 +O=c1cc(Cn2c(C3CCC3)nc3ccncc32)c2ccc(F)c(F)c2[nH]1 +CCn1c(=O)c(-c2ccc(F)c(NC(=O)Nc3cc(C(C)(C)C)no3)c2)cc2cnc(NC)cc21 +COC(=O)CC1c2ccccc2N=C(Nc2ccc(-c3ccccc3)cc2)N1CCCCCN +Cc1cc(Oc2ccc(-c3nc4cc(C(N)=O)ccc4[nH]3)cc2)ccc1F +Cc1nc(-c2ccc(Cl)cn2)nc(NCC(NCc2ccccc2)c2ccccc2)c1Cl +CC(C)(N)CNC(=O)CC1CCC2(CC1)OOC1(O2)C2CC3CC(C2)CC1C3 +Cc1cc(Oc2cc(NC(=O)C3CC3)ncn2)ccc1NC(=O)Nc1cc(OC(F)(F)F)ccc1F +O=C(O)c1nc2ccccc2n(C2CC3CCC(C2)N3C23CC4CC(CC(C4)C2)C3)c1=O +c1cncc(-c2ccc3c(c2)CCc2nnc(C4CC4)n2-3)c1 +NC1=NCC(Cc2ccc(-c3ccccc3)cc2)C(N)=N1 +CNC(=O)C1Cc2cc(-c3ccccc3)ccc2N1C(=O)COc1ccc(F)cc1 +COC(=O)c1cc(OC(=O)c2ccc(OC)c(O)c2)c(OC)cc1CCN(C)C +CCOC(=O)C1=CC2C(=O)c3cccnc3C(=O)C2C(c2ccc(Cl)cc2)=N1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2ccc(C)c3ccccc23)c(Cl)c1 +COc1ccc(-c2nn(C(C)(C)C)cc2CN2CCCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc1 +CC(Oc1cc(-c2ccc3ncn(C)c3c2)cc2ncccc12)C1CNC(=O)C1 +CN1CCC2(CCCCCc3ccccc3)c3cc(O)ccc3OC2C1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(F)cc4)cn3CCN3CCCC3)CC2)c1Br +CC(C)c1cccc(C(C)C)c1NC(=O)OCC(Nc1ccc(CN(C)C)cc1)c1ccccc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1nc(-c2ccc(Cl)c(OC(F)(F)F)c2)no1 +NS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 +CSc1c(Cl)nc(-c2ccc(NC(=O)Nc3ccc4oc(=O)[nH]c4c3)cc2)nc1N1CCOCC1 +N#Cc1ccccc1-c1ccc(C(=O)N(Cc2ccccc2)CC2CCCO2)cc1 +COc1ccccc1CNC1C2CC3CCOC(C2)N3C1C(c1ccccc1)c1ccccc1 +CCC(CC)N1C(=O)C(C)(CC2OC(=O)NC2=O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COc1c(C(=O)N2CCC(F)(CNCc3ccc(C)cn3)CC2)csc1Br +O=C(C(=O)C(Br)c1ccccc1)C(Br)c1ccccc1 +O=C(O)COc1cc(Cl)ccc1C(=O)NCc1c(Br)c(Br)c(Br)c(Br)c1Br +O=C(CN(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NO +COc1nc(Nc2c(C)cc(C)cc2C)nc(NC2CCN(Cc3ccc(C#N)cc3)CC2)n1 +CCc1ccc(Cc2cc3c(cc2Cl)OCCCCOCC2OC3C(O)C(O)C2O)cc1 +Cn1cc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3=CCC2(C)C1(O)C(=O)CO +Nc1c(Br)cc(C(=O)NC2CN3CCC2CC3)c2[nH]cnc12 +CON=C(CCN1CCN(c2ccccn2)CC1)c1cccc(C)c1 +NC(CC(=O)NC1(c2cccc(-c3cnc(C4CCCCN4)s3)c2)CCS(=O)(=O)CC1)Cc1ccccc1F +Cc1c(C(C)c2c(F)cccc2F)nc(SCc2ccc(C#N)cc2)[nH]c1=O +CCN(CC)C(=O)CN1CCCC(c2nc3ccccc3n2Cc2ccc(F)cc2)C1 +Cc1cc(OCCCc2c(C(=O)O)sc3cc(Cl)ccc23)cc(C)c1Cl +CS(=O)(=O)Nc1cc(C(O)CNC2CCN(c3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)CC2)ccc1O +O=C(Nc1ccc(-c2nnc(NCCCCN3CCCCC3)o2)cc1)c1ccccc1F +CCCCCCCCC=CCCCCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 +O=C(CCCCn1cc(-c2ncnc3[nH]ccc23)cn1)NO +CSCC(NC(=O)c1ccc(C#Cc2ccccc2)cc1)C(=O)NO +COc1ccc(CC(O)c2cc(OC)c(OC)c(OC)c2)cc1O +COc1ccc(NC(=O)Nc2ccc(Oc3ncnc4ccn(C)c34)cc2Cl)cc1C(F)(F)F +CC(C)C(=O)Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CC1C2Cc3cc(Cl)c(O)c(Cl)c3C1(C)CCN2Cc1ccccc1 +NC(=O)c1cccc2c1C(=O)N(C1CCN(C(=O)C3CCCCC3)CC1)C2 +CC(C)(C(=O)OC1(C)C2CC3CC(C2)CC1C3)c1cccnc1 +O=C(C1CNCCC1(O)c1ccc(F)c(F)c1)N(Cc1cn(Cc2ccc(OC(F)F)cc2)c2cccc(F)c12)C1CC1 +CC(=O)Nc1ccc(-c2ccc(C3COC4(C=CC(=O)C=C4)O3)cc2)cc1 +Oc1ccc2nc(Cl)n(-c3ccccc3SC(F)(F)F)c2n1 +Nc1ccc(-c2ccsc2)cc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 +Cc1nc2cnccc2n1-c1ccc(-c2nc3ccccc3[nH]2)cc1 +N#Cc1c(-c2ccccc2)nc2[nH]nc(-c3ccccc3)c2c1C1CC1 +O=C(Nc1ccc(CC(NC(=O)C2CCC(=O)N2Cc2ccccc2)C(=O)O)cc1)c1ccccc1 +CONC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(CCS(=O)(=O)NC(C)=O)cc3)ncc2c1=O +CN(CC(=O)N1CCN(c2ccccc2)CC1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +COc1ccc(-c2nn(-c3ccccc3)cc2CN2CCCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc1 +COc1ccc(C(=O)c2c(C)n(Cc3cc(OC(C)C(=O)O)ccc3F)c3ncccc23)cc1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCC3)CC2)c1)c1ccc(Cl)cc1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(-c3nn[nH]n3)cnc3ccccc23)cc1 +O=C(O)CC1CCn2c1c(Sc1ccc(Cl)c(Cl)c1)c1c(CC3CC3)nccc12 +N#CC1CCCN1C(=O)c1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 +Fc1ccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1F +COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2nc3ccc(F)cn3c2C)cc1 +COC(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(N(CC(=O)N(C)C)C(C)=O)cc1)c1ccccc1 +CC(C)Cc1ccc(C(C)c2nc3cc(Cl)ccc3n2Cc2ccccc2)cc1 +Nc1nc(C(=O)NCc2ccccn2)cc(-c2ccccc2F)n1 +Cc1ccccc1C1CCc2cc(Oc3nc(C)c(C(=O)NCCO)s3)ccc2O1 +O=C(NCC(CC1CC1)c1ccc(C(F)(F)F)nc1)c1cccc(Cl)c1F +COc1cc(OC)c(C(=O)c2ccc(F)cc2)c(O)c1Br +Nc1cccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)c1 +O=C(NCCCNCCCCCNCCCNC(=O)NCc1ccccc1)NCc1ccccc1 +N=C(NCCCCCCCCCCCCNC(=N)C1CC1)C1CC1 +N=c1c2nc[nH]c2nc2n1CCC2=Cc1ccccc1Br +O=C(O)c1nc2c(O)nc3cc(Cl)c(-n4cnnc4)cc3n2n1 +CN(CC(CCN1CCC(c2nc3ccccc3[nH]2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +Cn1ccc(S(=O)(=O)NC(CNC(=O)C2=NOC(CCCCN=C(N)N)C2)C(=O)O)n1 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+CC1(C)c2cc(OCC(O)C(O)CO)ccc2C(=O)c2c1oc1cc(OC(=O)NCc3ccccc3)ccc21 +NC1CCC(CNC(=O)C2CCCN2C(=O)CC(c2ccccc2)c2ccncc2)CC1 +Nc1nccc2cc(CC(C(=O)O)N3CCC(NS(=O)(=O)c4cnc(N5CCCC5)s4)C3=O)c(C(F)(F)F)cc12 +Cn1c2ccccc2c2nnc(SCCNc3ccnc4cc(Cl)ccc34)nc21 +CCCC[n+]1c(C=Cc2ccc(N(C)C)cc2)sc2ccccc21 +Cc1ccccc1Nc1nc2ccc(CC(=O)N3CC(F)CC3C(=O)N3CCN(CC(=O)O)CC3)cc2o1 +O=S(=O)(c1cccc2ccccc12)c1n[nH]c2ccc(CN3CCNCC3)cc12 +O=C1OC2(CCC(C(=O)Nc3ncc(-c4ccccc4F)cn3)CC2)c2cccnc21 +Cc1ccc(S(=O)(=O)n2cc(C)c3ccc(C(=O)Nc4c(Cl)cncc4Cl)cc32)cc1 +CC1(C)Cc2nc(C3CCCC3)c(C(=O)c3ccc(C(F)(F)F)cc3)c(C3CCCCC3)c2C(O)C1 +O=C(O)CNC(=O)c1c(=O)oc(O)c2cccc(-c3ccc(Cl)cc3)c12 +COc1ccc(-n2c(C)cc(-c3nnc4n3CCCCC4)c2C)cc1 +COC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O +CNC(C)C(=O)NC1C(=O)N(Cc2noc3cc(Br)ccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)C1C +CC1(C)CN(C2CC(c3ccc(F)cc3)c3ccc(Cl)cc32)CCN1 +O=C(c1cc[nH]n1)N1CCCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1 +CC(=O)N1CCN(c2ccc(CN(CC(C)C)S(=O)(=O)Cc3ccccc3)c(F)c2)CC1 +C=C1CC(C2CC34C=CC2(OC)C2Oc5c(O[Si](C)(C)C(C)(C)C)ccc6c5C23CCN(C)C4C6)OC1=O +CCCCCc1ccc(-c2cc3cn(C4CC(O)C(CO)O4)c(=O)nc3o2)cc1 +CS(=O)(=O)c1ccnc2c1c(Sc1ccc(C(F)(F)F)cc1)c1n2CCCC1CC(=O)O +CN1CCCN(C(=O)NCCc2c[nH]c3ccc4c(c23)CCNC4=O)CC1 +CC(C)(CCCCCCC(C)(C)C(=O)Oc1ccc2c(c1)C13CCCCC1C(C2)N(CC1CCC1)CC3)C(=O)O +CCc1cc2c(C3=NN(CCCOc4ccc(C5=NNC(=O)CC5C)cc4)C(=O)CC3C)ccc(OC)n2n1 +CC(C)CN(Cc1ccc(-c2cccc(NS(C)(=O)=O)c2)s1)S(=O)(=O)Cc1ccccc1 +N#Cc1ccccc1-n1cc(C(=O)OC2CC3COCC(C2)N3)c2ccccc21 +COc1ccc(CN2C(=O)CNC(c3cccc(C)c3)(C(Oc3nc(C)cc(C)n3)C(=O)O)c3ccccc32)cc1 +O=C(NCc1ccccc1)OC1COC2C(OC(=O)c3ccc([N+](=O)[O-])cc3)COC12 +O=C(CCCNCC1CCCCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 +CC(C)(C#N)c1cccc(NC(=O)c2ccc(F)c(Nc3ncnc4cnc(N5CCOCC5)nc34)c2)c1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(N3CCN(C(C)C)CC3)nc12 +CN(C)CCCN1C(=O)c2c(c3c4cc(O)ccc4[nH]c3c3cc4ccccc4cc23)C1=O +CCN(CC)CCCCNc1c2ccccc2[n+](C)c2c1[nH]c1ccccc12 +COc1cccc(C(O)(c2cccc(OC)c2)C2CCN(C(=O)Oc3ccc([N+](=O)[O-])cc3)CC2)c1 +Cc1nc(C(=O)Nc2ccc3c(c2)C2(CCOC(N)=N2)c2cc(-c4ccnc(F)c4)nc(F)c2O3)cs1 +CC(C)Cc1ccc(Oc2ccc(S(=O)(=O)Nc3nccs3)cc2F)c(-c2ccnn2C)c1 +C=C1C(=O)OC2CC1(C)OCC2C1CCC2C3CC4OC45CC(O)CC(=O)C5(C)C3CCC12C +COc1ccc(Cn2cc(C(=N)S)c3c(N)ncnc32)cc1 +Cc1cc(C(=O)Nc2ccccc2)c2ccc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)cc2n1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCN(Cc2cccc3c2N(C)CC3)C1 +O=c1cc(-c2cc(NC3CCOCC3)ncn2)ccn1C(CO)c1ccc(Cl)c(F)c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1Cc3ccccc3C1)CC2 +Fc1cc(-c2cc[nH]c(=Nc3ccc(-n4cnc(N5CCOCC5)n4)cc3)n2)cc(N2CCOCC2)c1 +Cc1cc(N2CCN(C(=O)c3ccoc3)CC2)n2nc(-c3ccncc3)cc2n1 +CNc1nc(C)c(-c2nc(Nc3cccc(S(=O)(=O)NCCOC)c3)ncc2F)s1 +O=C(NCc1ccccc1F)c1nc(-c2cccs2)nc(O)c1O +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OCC(=O)O)cc2)C1O +C=CCC1Oc2ccc(Br)c(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +COCC(CO)NC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +COc1ccc(-c2nc3ccccc3n2C(=O)c2cccc3ccccc23)cc1 +COC1CCCC1NC(=O)Nc1cc2[nH]nc(N)c2cn1 +CC1(C)OCC(=O)Nc2ccc(-c3ccc(C#N)[nH]3)cc21 +CCN(c1nc(C)cc(-c2ccccc2C(F)(F)F)n1)c1ccc(S(C)(=O)=O)cc1Br +Nc1nc2c(s1)CCCC2C(=O)Nc1ccc(CC2CCC(C(O)c3ccccc3)N2)cc1 +CCOC(=O)C1CCCN(c2cccnc2Oc2ccc(Nc3ccccn3)cc2)C1 +COc1cc2c(Oc3ccc(NC(=O)c4cn(-c5ccccc5OC)cn4)cc3F)ccnc2cc1OCCCN1CCOCC1 +COc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)o2)CC1 +O=C(O)Cc1nn(Cc2nc(-c3c(F)cccc3Cl)no2)c(=O)c2ccccc12 +COc1cccc(C(C)Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +Cc1c(Cl)cccc1N1CCN(CCCNC(=O)c2nc(C)n(CC(C)C)c2C)CC1 +CCc1c(C)[nH]c2cc(OCCOc3ccccc3)c(C)cc2c1=O +CC(C)(C)C(=O)N(CC=Cc1cnc2c(c1)CC1(C2)C(=O)Nc2ncccc21)C1CCCCCC1 +Cn1cc(-c2ccn3c(-c4ccccc4)c(-c4ccc(C5(N)CCC5)cc4)nc3c2)cn1 +O=C(NCCc1c[nH]c2ccc(O)cc12)Oc1cccc(-c2ccccc2)c1 +CC1CNc2c(sc3ccc4oc(-c5ccccc5)cc4c23)C(=O)N1 +O=C(NCC(c1cnc(C(F)(F)F)nc1)N1CCC(F)(F)CC1)c1c(Cl)ccc2nc(N3CCC(O)C3)ccc12 +CC(=O)NCCNc1nc(-c2ccccc2)nc2[nH]c(C(=O)N3CCN(CCCc4ccccc4)CC3)cc12 +COCCOCCOc1ccc(-c2cnc(N3CCOCC3)c3nc(CCc4ccc5ccccc5n4)cn23)cc1 +CC(C)CC(NC(=O)CCN(C)C)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C2COCC2c2ccc(Cl)cc2)CC1 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+CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ccc(F)cc3)cs2)CO1 +COc1cc2cc(C(=O)CCC3CC[N+](C)(CC(=O)OC(C)(C)C)CC3)sc2cc1OC +Nc1nc2c(c(=O)n(CC3CC3)c(=O)n2CC2CC2)n1S(=O)(=O)c1ccc(Cl)cc1 +COc1cc(CC(=O)N2CCc3c(n(Cc4sc(C(F)(F)F)nc4C)c4ncccc34)C2)cc(OC)c1C(=O)O +CCC#CC1(C(F)(F)F)NC(=O)Nc2ccc(Cl)cc21 +CC(C)OC(=O)C1=CN(C(=O)c2ccc(CCN3CCOCC3)cc2)CC(C)(C)c2c1[nH]c1ccccc21 +Cc1cccc(Cl)c1NC(=O)c1cnc(NC2CCCCC2)s1 +CC(C)OCCCN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCC1 +NC(=O)c1coc(C(=O)CCCCCCc2ccccc2)n1 +COc1cc(NC(=O)c2ccc([N+](=O)[O-])o2)ccc1NC(=O)c1cccs1 +CNCc1cc(-c2ccccc2)c(S(=O)(=O)c2ccccc2)s1 +COCc1nnc(-c2cc(C(=O)N3CCC(F)(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCC2)[nH]1 +COc1c(O)cccc1C(O)C1CCN(CCc2ccc(F)cc2)CC1 +CC(=NNC(N)=O)c1ccc2ncc(C(O)c3c(F)cc4ncccc4c3F)n2n1 +CCNCc1ccc(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(CC)c3)no2)s1 +COc1ccc(-c2ccc(=O)n(CCCc3ccccc3)n2)cc1OC +Cc1cc(C2C(=O)Nc3ccc(-c4cncc(OCC(N)Cc5c[nH]c6ccccc56)c4)cc32)oc1C +COc1cccc(OC)c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)c(F)c1 +COc1cc(C=CC(=O)OC(C)CCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)ccc1O +Fc1cc(C(CC2CNC2)Oc2cccc(Cl)c2)ccc1Cl +CC(=O)NC1CCCN(c2ncnc(C)c2C#Cc2ccc(N)nc2)C1 +CNc1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c2cnn(C(C)C)c2n1 +COCc1ncc(Cc2cnc3ccc(O)cc3c2)c2cc(OC)c(OC)cc12 +COc1cnc(Cl)nc1-c1ccc2c(c1)CCC(c1cccnc1)N2C(=O)c1cc(Cl)c(O)cc1O +Nc1nn(-c2cncc(-n3ccc(CC(=O)O)c3)n2)c2ccccc12 +CCOC(=O)c1c[nH]c2ncnc(-c3cccc(NC(=O)C=CCN(C)C)c3)c12 +COc1ccccc1Cc1nc2ccc(-c3nn(C4CCC(N5CCOCC5)CC4)c4ncnc(N)c34)cc2[nH]1 +Cc1cc(COc2ccc(NC(=O)C3CCN(S(=O)(=O)c4cn(C)cn4)CC3C(=O)NO)cc2)c2ccccc2n1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4cnsc4)ncc23)ccn1 +N#CCc1c(C(=O)N2Cc3ccc(Br)cc3C2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +Cc1ccc(CCNc2nc(CCc3ccccc3)nc3sc(C(=O)O)c(C)c23)cc1 +Cc1ccc(C(=O)Nc2cccc3cnccc23)cc1Nc1nc2ccccc2n1-c1cc(N)ncn1 +O=C(NC1CCN(Cc2ccc3ccccc3c2)CC1)c1ccc(Cl)cc1 +CN(C)c1ccc(C=NNc2nc3ccccc3[nH]c2=O)cc1 +Cc1ccc(-n2nccn2)c(C(=O)N2CCC2c2noc(-c3ccccc3OC(F)(F)F)n2)c1 +Cc1occc1-c1nc(N)c(OCC(N)Cc2c[nH]c3ccccc23)cc1-c1ccc2[nH]nc(C)c2c1 +O=C(Cc1ccccc1)NC1C(CO)OC(n2cnc3c(NC4CCCC4)ncnc32)C1O +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)(C)c2ccc(F)cc2)c1 +CC1CN(C(=O)CC(N)C(=O)N2Cc3ccccc3C2)CCN1C(c1ccc(F)cc1)c1ccc(F)cc1 +Cc1cn(C2C=CC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O +COCCNC1CCC(Nc2cc(-c3nc(NCC4CCOCC4)ccc3F)c(Cl)cn2)CC1 +Cc1[nH]c(C=C2C(=O)Nc3ccccc32)c(C)c1CCCN1CCN(C)CC1 +O=C(c1cccnc1)N1N=C(c2ccc(O)cc2)CC1c1cccc(Br)c1 +O=C(O)Cn1nnc(-c2cc(N3CCC4(CCc5c(OC(F)(F)F)cccc5O4)CC3)no2)n1 +CC(C)Nc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1 +CC(C)CC(NC(=O)Cc1cccc(F)c1)C(=O)NC(CC1CCCCC1)C(O)C(=O)Cc1ccccc1 +Nc1cccc2c1[nH]c(=O)c1nn(-c3ccc(O)cc3)c(=O)n12 +CC1CN(C2CCC(n3cc(C(N)=O)c(Nc4ccc(S(=O)(=O)C(F)(F)F)cc4)n3)C(C#N)C2)C1 +CC12CCC(=O)C=C1CCC1C2CCC2(C)C(CC=NO)CCC12 +O=C(Nc1n[nH]c2ncc(-c3ccccc3)cc12)C1CCCC1 +Cn1cc(Nc2ncc(C3CC3)c(NCCCNC(=O)C3CCC3)n2)cn1 +CCC1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OCC(C)C)nc2N1C1CCCC1 +O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2ccccc2F)CC1 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+O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(Cl)c(-c2cc[nH]n2)c1 +COc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1OCCCCCCn1ccnc1[N+](=O)[O-] +COc1cc(C(N)=O)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3ccncc32)C1c1cccc(Cl)c1F +CC#CCOc1ccc(S(=O)(=O)C2CCC(S)C2)cc1 +CC(C)OC(=O)N1CCC(C(NS(=O)(=O)c2ccc(-c3ccc(OC(F)(F)F)cc3)s2)C(=O)O)CC1 +COC(=O)c1ccccc1N1CCC(CNc2nccc(C)c2NC(=O)CC#N)CC1 +O=C1NC(CCN2CCN(c3ccccc3)CC2)c2ccccc21 +N#Cc1cc(S(=O)(=O)Nc2nncs2)ccc1Oc1ccc(Cl)cc1-c1ccnc(N2CCC2)c1 +OC(CN1CCN(CC=Cc2ccccc2)CC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc21 +O=C(Nc1ccc(Oc2ccc(Cl)cc2)c(Cl)c1)c1cc([N+](=O)[O-])ccc1O +C=CC(=O)Nc1cc(N)nc(Sc2c(OCC)nc(N3CCN(C)CC3)nc2OCC)n1 +CC(C)C(NC(=O)NC1CCCC1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1 +Cc1c(C(=O)NCCc2ccc(Cl)cc2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(C)ccc1C +CN1CCN(CCc2ccc(C3=CCC4CN(Cc5ccccc5)CC34)cc2)CC1 +COc1n[nH]c2cc(NC(=O)NCc3c(C)cccc3Cl)ncc12 +CC12C=CC(=O)C=C1C1(CC1)CC1C2CCC2(C)C(c3cccnc3)=CCC12 +Cc1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)COc3ccc(O)cc3)cc2)cc1 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+Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(c1)OCc1ccccc1C2=O +COc1ccc(CC(N)C(=O)N2CC(F)CC2C#N)cc1 +Cc1c(Cl)cccc1S(=O)(=O)NCC1(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)CC1 +COc1cnn(C)c(=O)c1-c1ccc(CC(NC(=O)c2c(Cl)cccc2Cl)C(=O)O)cc1 +COc1ccc2c(c1F)C(=O)N(CC1(C#Cc3ccc(CN4CCOCC4)nc3)NC(=O)NC1=O)C2 +Fc1ccc(C(OCCC2CCN(CC3Cc4ccccc4CN3)CC2)c2ccc(F)cc2)cc1 +C=C(CC)C(=O)c1ccc(OCC(=O)NCCc2ccc(O)c(OC)c2)c(Cl)c1Cl +CCCCc1oc2ccccc2c1C(=O)c1ccc(OCCNCC)c(I)c1 +COc1ccc2c(c1)CC(NCCN1CCC(CNS(=O)(=O)c3cccc4ccccc34)CC1)CCC2 +Cc1c(Oc2ccc(Cl)cc2)c2cccnc2n1Cc1cc(OC(C)C(=O)O)ccc1Cl +CCCCCN(C)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12 +Nc1ncc(-c2cc(Nc3cnc4ccccc4c3)nc(N3CCOCC3)n2)cn1 +O=C(N1CCN(Cc2ccccc2)CC1)N1CC(OC(c2ccc(Cl)cc2)c2cccnc2Cl)C1 +CN(C)C(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccc(OCc3ccccc3)cc21 +COc1ccc(-n2nc(C(=O)N3CCCC3)cc2-c2ccc(Cl)cc2)cc1 +COc1ccc(CCCO)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1 +O=C(Cc1ccc(O)cc1)NN=C1C(=O)Nc2ccc(S(=O)(=O)NCCN3CCOCC3)cc21 +COc1ccc(-c2ccc(C(=O)N(C)c3cccc(OC)c3)s2)cc1 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+COc1cc(NC(=O)C2COc3ccc(Cl)cc3C2)ccc1-c1cn[nH]c1 +COC(=O)CCC(=O)OC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +COC(=O)CCSC(=O)C1(C(O)C2C=CCCC2)NC(=O)C(CCCl)C1(C)O +COc1cc(C(F)(F)F)cc(SC)c1C(=O)NC1COCCC1NC1(C)CCCC1 +CC1(C)C(=O)Nc2nc(-c3nn(Cc4ncccc4F)c4cc(Cl)ccc34)nnc21 +CC(C)(C)c1ccc(N(Cc2ccc(C(=O)NCC(O)C(=O)O)cc2)C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 +COc1ccc(CNC2CCN(CCN3CCCCC3)C(c3ccc(OCc4ccccc4)cc3)C2)cc1OC +CC1(N2C(=O)c3ccccc3C2=O)CCC(=O)NC1=O +CC(=O)NC1CCCN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)C1 +FC(F)(F)c1ccc2nc(COc3cc4c(cc3Cl)OCO4)[nH]c2c1 +Cc1c(Cc2ccccn2)nnc(N2CCN(c3cnc(C(C)(C)O)cn3)C(C)C2)c1C +COc1cc(-n2cnc3cc(-c4ccc(F)cc4)sc3c2=O)ccc1OCCN1CCCC1 +CC(C)c1c(Sc2ccccc2)n(COCc2ccccc2)c(=O)[nH]c1=O +O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Cl)ccc1O +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ON=C(C)N +COc1ccc(C2CC2COc2nc(C)ncc2-c2cc(=O)n(C)cc2SC)nc1 +COC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 +COc1ccc(C#Cc2cccc(C#Cc3ccc(OC)cc3)[n+]2C)cc1 +COc1cnc(N2CCC(C3CC3COCc3ccc(S(C)(=O)=O)cc3F)CC2)nc1 +O=C(COc1ccccc1)N1CCCCC1c1csc(-c2n[nH]c3ccccc23)n1 +COc1cc(-c2cc(-c3ccc(N4CCNCC4)cc3)cnc2Cl)cc(OC)c1OC +COc1ccc(-c2cn(CCC(C)(C(=O)NO)S(C)(=O)=O)nn2)c(F)c1 +CCc1c(C(F)(F)F)nn(C)c1Oc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F +O=C1N(CCCCN2CCN(c3nsc4ccccc34)CC2)CSC12Cc1ccccc1C2 +Cc1c(Oc2ccc(Cl)cc2)c2cccnc2n1Cc1ccc(F)c(OC(C)C(=O)O)c1 +C[N+]1(C)C2CCC1CC(CC(O)(c1cccc(Cl)c1)c1cccc(Cl)c1)C2 +Cc1ccc(NC(=O)c2ccc(NC(=O)CCl)cc2)cc1Nc1nccc(-c2cccnc2)n1 +Clc1ccc2c(c1)-c1ncnn1Cc1c(C3CC3)ncn1-2 +CCOC(=O)N1CCN(C(=O)c2ccc(-c3ncnc(CC)c3C#Cc3ccc(N)nc3)cc2C)CC1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCC(O)C2)c(-c2cncc(F)c2)c1 +Cc1cccc(C2=NC(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)C(=O)Nc3c(Cl)cccc32)c1 +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3cccc4[nH]nc(C)c34)cc(C)c2C1 +O=C1CCc2cc(Nc3ncc(C(F)(F)F)c(NCc4ccccn4)n3)ccc2N1 +COc1ccc(C(NC(=O)COc2ccc(C)cc2)c2cc(Cl)c3cccnc3c2O)cc1 +NC(=O)c1c(NC(=O)c2ccc(Cl)cc2)sc2c1CCCC2 +COc1cccc(Cn2cnc3c(N(C)C)nc(C(F)(F)F)nc32)c1 +CN(C)C1CCN(c2ccc(Nc3ncc4c5ccnc(O)c5n(C5CCC(C)(C)CC5)c4n3)nn2)CC1 +Clc1ccc2c(NCCNc3nc(Cl)cc(Cl)n3)ccnc2c1 +O=S(=O)(NCC1CC1)c1ccc(NN2CCOCC2)cc1C(F)(F)F +CCOc1cc(CN2CC3(CC(c4ccc(C(=O)O)cc4)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +Cc1cc(N(C)C)nc2ccc(Cc3cnc(N)nc3N)cc12 +Cc1cn(Cc2ccc(F)c(F)c2)c2c(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 +CC(C)C1CCNc2cc3nc(O)cc(C(F)(F)F)c3cc21 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(COc3ccc(NC(=O)OC(C)(C)C)cc3)cc2)cc1)C(=O)O +CCCCCCCCCCCCCC(=O)NCCc1ccc(OS(N)(=O)=O)cc1 +Cc1cccc(CC(NC(=O)C(c2ccccc2)c2ccccc2)C(=O)NC(C#N)CCCc2cccc(C(=O)O)c2)c1 +Clc1ccc(C=Cc2ccc(-c3ccc(I)s3)s2)cc1 +COc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)cc1OC +CCOc1nc(-c2ccccc2)ncc1C(=O)N1CCC(c2nc3ccccc3[nH]2)CC1 +c1ccc(CCN2CC(c3[nH]c(-c4ccccc4)nc3-c3ccccn3)CCC2c2ccccc2)cc1 +Nc1nc(N)c2c(CCCc3csc(C(=O)NC(CCC(=O)O)C(=O)O)c3)coc2n1 +CC(C)c1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)cc1 +CC(C)Oc1ccc(Nc2ncc(C(=O)NN)c(=O)n2Cc2ccc(Cl)cc2)cc1F +CNC(=O)C(O)C(O)c1cn(-c2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)c2ccccc12 +COc1ccc(Nc2cc(S(=O)(=O)O)c(N)c3c2C(=O)c2ccccc2C3=O)cc1 +FC(F)(F)c1ccc(Nc2noc3cc(-c4cccc(C(F)(F)F)c4)ccc23)cc1 +O=C(C=Cc1ccc(O)c(O)c1)NCC(NC(=O)C=Cc1ccc(O)c(O)c1)C(=O)O +COc1cccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)c1 +CC1COc2c(NCCCc3ccccc3)c(F)c(N)c3c(=O)c(C(=O)O)cn1c23 +CNc1nc(Nc2ccc(C(=O)N3CCN(S(C)(=O)=O)CC3)cc2OC)ncc1Cl +CC(=O)Nc1ccc(C)c(-c2ccc(C(=O)NCC3CC3)cc2)c1 +CN(C1CCc2c(CC(=O)O)c3cccc(F)c3n2C1)S(=O)(=O)c1ccc(F)cc1 +CCCN1CCC23Cc4nc5ccccc5cc4CC2(O)C1Cc1ccc(O)cc13 +CCN(CC)C(=O)C1CCC2C3CC=C4N(O)C(=O)CCC4(C)C3CCC12C +COc1cc2[nH]c(C)c(-c3cccc(CO)c3)c(=O)c2cc1Cl +NS(=O)(=O)c1ccc(-n2cc(C=NNc3nc(-c4cc5ccccc5oc4=O)cs3)c(-c3ccc(Cl)cc3)n2)cc1 +O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 +c1cc(-c2cnc(N3CCCC3)c(N3CCNCC3)n2)c2cc[nH]c2n1 +O=C(O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1 +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CCCC(C)(C)C)CC(O)CC1O +COc1cccc(C=C2SC(c3ccccc3)=NC2=O)c1O +O=C(Nc1cncc(Oc2cncc(F)c2)n1)c1cc(Cl)ccc1F +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N4CCCC4)ncc3Cl)C2)cc1 +O=C(Cc1ccc(O)cc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc(O)cc3)s2)s1 +CC(C)[S+]([O-])c1ccccc1Nc1nc(Nc2ccc(CN3CCN(C)CC3)cc2)ncc1Cl +O=C(NCCCCN1CCC1)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COc1cccc(CNC(=O)c2cc3ccc(-c4cn[nH]c4)nc3n2CCN(C)C)c1 +NS(=O)(=O)c1ccc(-n2cc(-c3ccc(Br)cc3)c(C(F)(F)F)n2)cc1 +COc1cc(-c2cccc(OC)c2Cl)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +COc1cccc(CN2CCN(CCOc3cccc4nc(C)ccc34)CC2)c1 +COCC(COC)n1cc(Cl)nc(Nc2c(Cl)cc(OCF)cc2Cl)c1=O +Cc1cc2cc(F)ccc2nc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +CC(=O)NC1C(COCCCCc2ccccc2)NC(CO)C(O)C1O +CCCNc1nccc(N2CCC(Oc3ccc(C(C)C(=O)NC4CC4)cc3)C2)c1F +Cc1ccc(-c2nc(C(C)(C)C)c[nH]2)cc1S(=O)(=O)N1CCOCC1 +COc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccccc3)nn2)CC1 +COc1cc(OCc2csc(N3CCC(F)CC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)C2=NOC(CCCCNc3ncc[nH]3)C2)C(=O)O)c(C)c1 +CCOc1cc(N2CCNCC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1Cc1ccccc1)CC2 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ncc[nH]3)cc12 +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2oc(CN3CCCC3)cc2c1 +[C-]#[N+]c1cc(-c2ccnc(Nc3ccn(C4CCNCC4)n3)c2)ccc1OCC1CCC1 +CCc1c(C)nc(-c2ccccc2O)n(CCc2ccccc2)c1=O +COc1cccc(-c2nccnc2C2CN(c3nc4ccccc4cc3C#N)C2)c1 +Cc1c(Cc2c(CO)nc3c(N)cc(N4CCOCC4)nn23)cccc1C(F)(F)F +CCc1nc2cc3c(cc2o1)CCN(CCCSc1nnc(-c2ocnc2C)n1C)CC3 +CCCCc1nc2[nH]cnc2c2nc(-c3ccc(OC)cc3)nn12 +O=C(O)c1cc(C(F)(F)F)ccc1N1CCC(Cc2ccc(F)cc2)C1 +Clc1ccc2[nH]c3c(NCCC4=CCCCC4)ncnc3c2c1 +N=C(N)c1cccc(OCCN(Cc2ccccc2)C(=O)c2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +COC(=O)NC(C)Cc1ccc(C#Cc2cnc(NC(C)C)nc2)cc1 +CC(=O)c1ccc(Cn2nc3c(c2Nc2ccc(F)cc2)C(=O)N(C)C2=NC(C)(C)CN23)cc1 +COc1ccc(OC)c(-n2c(-c3ccccc3)nc3ccccc3c2=N)c1 +Cc1ccc(-c2cnc(C(=O)CCCCCCc3ccccc3)o2)nc1 +CS(=O)(=O)c1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)cn2)cc(C(F)(F)F)c1 +Cc1nc2cc(Nc3cc(C4CCCNC4)nc4c(-c5cnn(C)c5)cnn34)ccc2s1 +Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(Cl)c(Cl)c1 +CC(=O)c1ccccc1-c1ccc(-c2ccc3c(c2)c(C)c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)cc1F +O=C(NCC1CCN(c2ccncc2)CC1)c1ccc(F)c(OCCc2ccc(Br)cc2)c1 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+Clc1ccc(C2(c3nnc4c(Oc5ccc6ccccc6c5)cccn34)CC2)cc1 +CC(C)NCC(C(=O)N1CCN(c2ncnc3c2C(C)CC3F)CC1)c1ccc(Cl)cc1 +O=C1c2ccccc2C(=O)N1CCCCN1CCN(Cc2ccccc2)CC1 +CCC(=O)Nc1ccc(Sc2nc(Nc3cc(C)[nH]n3)cc(N3CCN(C(C)(C)C)CC3)n2)cc1 +CCOc1ccc(Cl)cc1-c1ccc(C(=O)N=C(N)N)o1 +COc1cnc(Nc2ccc(N3CCOCC3)cc2)nc1-c1ccc(C(=O)NCC#N)cc1 +Cc1ccc(C(=O)Nc2ccc(C(F)(F)F)n(C)c2=O)cc1 +COCCOc1cc(NC(=O)N2CCCc3ccc(C=O)nc32)ncc1C#N +O=C(c1cc(Cl)cc(Cl)c1)c1cc(Br)ccc1OCCn1ccc(=O)[nH]c1=O +Cc1cc(Nc2nccc(-c3cc(C(C)(C)C#N)ccn3)n2)cc2cc(C(=O)N(C)C)[nH]c12 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3ncc4cccc(F)c43)c2)c2cncnc21 +CC12CCC(C(NC(=O)C(CC3CCCCC3)NC(=O)NC(CCONC(=N)N)C(=O)O)C1)C2(C)C +COCC(C)NCc1cccnc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(C)=O)CC1 +N=C(Nc1ccc2c(c1)CCN2C(=O)CN1CCCC1)c1cccs1 +CCNC(=O)NCC1CC1c1cccc2oc(CCCCc3ccccc3)cc12 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCN(CCCCCc2ccccc2)CC1 +CNc1cc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)cc(C(C)(C)C)n1 +Cc1cc2c(F)c(Oc3ncnn4cc(OCC(C)OS(=O)(=O)O)c(C)c34)ccc2[nH]1 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+O=C(NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1)c1ccc2ncccc2c1 +Cc1[nH]c(-c2ccccc2Oc2ccc(Cl)cc2)cc1C(N)=O +Nc1ncc2cc(-c3nccnc3OC3CN(c4ccc5ccccc5n4)C3)ccc2n1 +O=C(O)c1cc(-c2cccs2)n(Cc2cc(Br)ccc2OCc2ccccc2)n1 +CCOCCn1nc(C)c2nc(N3CCNCC3)nc(Nc3cc(C)ccn3)c21 +Cc1cc(Oc2cnc(NC(=O)C(OC3CCOC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)ccc1C(=O)O +CC1CN2C(=O)c3c(cccc3C(F)(F)F)C2CN1 +CNc1cc(Cn2c(C(=O)c3cc(C)cc(Cl)c3)c(C(C)C)c(=O)[nH]c2=O)ccn1 +CC(=O)Nc1c(O)[nH]c(=Nc2ccc(OC(C)C)cc2)n(Cc2ccc(Cl)cc2)c1=O +CN1CCN(C(=O)C(COCc2ccncc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 +O=c1[nH]c2ccc(Cl)cc2n1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CC1(C)OC(=O)N(C2CCC(n3c(=O)[nH]c4cnccc43)CC2)C1c1ccccc1 +C[S+]([O-])c1sc(C(=O)O)c(-c2ccc(C(C)(C)C)cc2)c1C#N +C=CCNC(=O)Nc1nc2cc(-c3cccnc3)c(OCCN3CCOCC3)nc2s1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1cnc(-c2ncc(C(F)(F)F)[nH]2)c(F)c1 +CC(C)Oc1ccc2c(c1)c(CN1CCN(C)CC1)cn2S(=O)(=O)c1ccccc1Br +COc1ccc(OCCN(CC(=O)NCc2ccccc2)Cc2ccc(F)c(F)c2)cc1OC +Cc1nc(-c2ccncc2)sc1C(=O)N1CCCC1c1cccc(C(=O)Nc2nc3c(s2)CC(N2CCOCC2)CC3)c1 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+CC(=O)N1CCC(c2cc(-c3cnc4[nH]cc(C(F)(F)F)c4c3)nn2C(C)C)CC1 +O=C(CCCC(=O)NCCCCNc1c2ccccc2nc2ccccc12)NCCCCNc1c2ccccc2nc2ccccc12 +N=C(N)c1ccc(CC(=O)CN2CCCCC(NS(=O)(=O)c3ccc4ccccc4c3)C2=O)cc1 +O=c1cc(-c2ccccc2)oc2cc(OCCCCN3CCN(CCCNc4c5c(nc6ccccc46)CCCC5)CC3)ccc12 +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccc(-c3cccnc3)cc2o1 +COc1ccc(C#Cc2cc(-c3nn(CCCN4CCOCC4)c4c3CN(S(C)(=O)=O)CC4)ccc2Cl)cc1 +COc1cccc(NC(=O)NC2C3CCN(CC3)C2Cc2cccnc2)c1 +Cc1cc(COC(=O)C2N3C(=O)C(NC(=O)COc4ccccc4)C3SC2(C)C)on1 +Cn1cnc(Nc2ncc(Cl)c(NC3CCC4(CC3)CCN(C(=O)CC#N)CC4)n2)c1 +Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)cc1 +COc1ccc2nc3cc(Cl)ccc3c(NCCCN(CCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)CC3CC3)c2c1 +Cc1ncn(CC(=O)NCCN)c1Cn1c(C)ccc(NS(=O)(=O)Cc2ccccc2)c1=O +CC1(C)Oc2ccc(C#N)cc2C(N2CCCC2=O)C1O +O=c1[nH]nc(CN2CCOC(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2c2ccccc2)[nH]1 +COc1ccc(NC(=NC#N)N2CCC(=C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)cc1 +CCN(CC)C(=O)C1CCC2C3CNC4=CC(=O)C5CC5C4(C)C3CCC12C +CC1CC(CS(=O)(=O)N2CCC(CO)CC2)CCC1N(C)c1ncnc2[nH]ccc12 +COc1cc(O)ccc1C=NNC(=O)Cc1cccc(O)c1 +CNc1nc(-c2nc3cnc(N4CCOCC4C)cc3n2C(C)COC)cn2c(C)nnc12 +O=C(NCCn1ccnn1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(CN(Cc1ccc([N+](=O)[O-])cc1)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NO +CC1CN2c3c(cc4c(C5CC5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CCc1c(Sc2ccccc2)n(COCC2CCCCC2)c(=S)[nH]c1=O +CC(=O)N1CCC(C(=O)N(CCCN2CCC(C(=O)NCc3ccc(Cl)cc3)CC2)c2cccc(Cl)c2)CC1 +Oc1nc2cnc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nc2[nH]1 +O=C(NCCn1cncn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(c1nn2c(C(F)(F)F)cc(C3CC3)cc2c1Cl)N1CCC2(CC1)OCC1(CO2)CC(O)C1 +Cc1cc(C)cc(C(=O)N2CCN(C(=O)CNC3CCN(Cc4cc[nH]c4)CC3)C(c3ccc(Cl)c(Cl)c3)C2)c1 +CNc1n[nH]c2cc(NC(=O)NC(COC)c3ccc(F)cc3)ncc12 +Nc1nc(-c2cc(N3CC(O)C(O)C3)ccc2O)cc(C2CCCCC2)n1 +O=C(c1ccc(Cn2c(=S)[nH]c3ccccc3c2=O)cc1)N1CCN(c2ccccn2)CC1 +Cc1csc2ncnc(N3CCC(CNCCC4CCCN4C)CC3)c12 +COc1ccc(OC)c(NCc2c[nH]c3nc(N)nc(O)c23)c1 +Cc1nc2ccccc2nc1CCc1nc(N2CCCC2)nn1C +COc1cc(Oc2ccncc2)c2c(Nc3c(Cl)ccc4c3OCO4)ncnc2c1 +CC(C)N(C)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +O=S(=O)(Nc1nncs1)c1ccc(Oc2ccc(Cl)cc2-c2ccn[nH]2)c(Cl)c1 +O=C(NC1CCN(CCCC(F)(F)F)CC1)c1cc(-c2c(O)cc(O)cc2Oc2ccc([N+](=O)[O-])cc2)on1 +CS(=O)(=O)c1ccc2nc(-c3ccc(-c4cccs4)cc3)[nH]c2c1 +NC1(c2ccc(-c3c(-c4ccccc4)ccn4ccnc34)cc2)CCC1 +Cc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)N(C)C3CCN(C)CC3)cc2)c(C)c1 +CCc1nccc(-c2ccc(C(=O)N3CCN(CC4CC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CSc1cccc(NC(=S)N(Cc2ccc(C)cc2)Cc2ccccn2)c1 +COc1ccc2c(c1)[nH]c(=O)n2CC(=O)Nc1ccc2c(c1)CC1(C2)C(=O)NC(=O)N1C +COc1ccc(Cc2cc(C34OCC(CO)(O3)C(O)C(O)C4O)ccc2Cl)cc1 +CC1CC(c2cc3c(C(F)(F)F)cccc3s2)CCN1CC(O)COc1cccc2[nH]ccc12 +CC(=NOC(C)C)c1ccc(Sc2cc(F)cc(C3CCOCC3)c2)cc1 +O=S(=O)(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)c1ccc(F)cc1 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(OCc3ccccc3)cc2)cc1 +CC(C(=O)OC1CC[N+](C)(C)CC1)(c1ccccc1)N1CCCC1 +O=C(O)CC1CCC(c2ccc(-c3noc(-c4ccc(C5CCCC5)cc4F)n3)cc2)N1 +CCCc1cc(NCC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)n[nH]1 +CN(C)c1ccc(-c2cc(-c3ccccc3)c3c(N)ncnc3n2)cc1 +CN(CCCCn1nc(-c2ccccc2)oc1=O)Cc1ccccc1 +Cc1ccc2c(c1)sc(-c1ccc(N(C)C)cc1)[n+]2C +Fc1ccc2c(c1)C(Nc1nc3ccccc3[nH]1)CCC2 +O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12 +Fc1cccc(F)c1C1CCC(N2CCN(c3ccccn3)CC2)CC1 +CC1=C2CC3C(CC=C4CC(O)CCC43C)C2CCC12OC1(C)CC(C)CNC1C2C +CNC(=O)C1OC(n2cnc3c(NOC)nc(C#Cc4ccccn4)nc32)C(O)C1O +CC12CCC(COc3cccc(-c4cn(C5CC(CO)C5)c5ncnc(N)c45)c3)(CC1)O2 +O=C(NC1COC1)c1cc2c(N3CCCC3c3ccccn3)ccnc2[nH]1 +Cc1cc(NCc2c(F)cccc2Cl)c2cccc(C(N)=O)c2n1 +Cc1ccc(-c2cc(C(=O)NCc3ccc(C)nn3)cc3c2ccn3C(C)C)nc1 +COc1ccc(NC(=O)c2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO +COc1cc(N2CCN(C)CC2)ccc1Nc1nc(N)n(C(=O)NCc2ccccc2S(C)(=O)=O)n1 +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ONC(C)C +Cc1ccc(N2CCOC(C(O)C(=O)Nc3ccc(C(=N)N)cc3)C2=O)cc1 +CCCCc1nc(Cl)c(CC(=O)O)n1Cc1ccc(C(=O)O)cc1 +COCCCCN1CCN(C(=O)c2cc3c(cc2C)[nH]c(=O)c2cnn(C4CCC4)c23)CC1C +COC(=O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2)c1 +Clc1ccc(-c2ccc(-c3nccn3-c3ccc(C4CCCCN4)cc3)o2)cc1 +OCCCNc1nc(Nc2ccccc2)nc(Nc2ccc(F)cc2)n1 +Cc1nc(N)c2cc(CN(C)C)cc(C(=O)Nc3ccn[nH]3)c2n1 +COCCOc1cc2ncnc(NC3=CC(=O)C=CC3=O)c2cc1OC +Fc1ccc2sc3c(c2c1)CCN(Cc1cnccc1C1CC1)C3 +COC(=O)C=Cc1ccc2c(c1)C(=O)C(=O)N2Cc1cccc(Br)c1 +N#Cc1ccccc1Oc1ccc(Nc2ncnc3cc[nH]c23)cc1Cl +Cc1ccc(-c2c[nH]c(C3(NCC4CCCCC4)CCCC3)n2)cc1 +NC(=O)c1ccc2[nH]c(-c3ccc(OC4CCCN(Cc5ccccc5)C4)cc3)nc2c1 +O=C1NCCc2[nH]c(-c3ccnc(-c4cncnc4)c3)cc21 +Cc1ccc(-c2cc(C(=O)NC(C)c3cnccn3)cc(N3C(=O)OCC3C(C)C)c2)c(F)c1 +CC(C)(O)c1c(C(N)=O)nc2n1C1CC(C1)c1cc(F)ccc1-2 +CC(C)(C)c1ccc(C(=O)Nc2cn3cc(Br)ccc3n2)cc1 +CCc1cccc(Nc2nc3cc(C(=O)O)ccc3c3sccc23)c1 +CC(C)N1CCN(c2cccc(S(=O)(=O)N3CCN(c4ccc(F)cc4C(F)(F)F)CC3C)c2)CC1 +Cc1ccc(N2CCc3ncnc(NCc4cccc(-n5cnnc5)c4)c3C2)c(C#N)c1 +CC#CCn1c(N2CCCC(N)C2)cc(=O)n(Cc2ccc3ccc(Cl)cc3n2)c1=O +CCCCCCCCCCCCCCOCC1COC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)C1 +Cn1c(OCC2CCN(c3ccc(CN4CCCCC4)cc3)CC2)nc(-c2ccncc2)cc1=O +CC(C)CNC(=O)c1ccc(-c2ccc(-c3ccco3)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2cc(C(F)(F)F)c3cc(F)ccc3n2)c1 +C=C(Br)C(=O)Nc1ccc(C(=O)C=Cc2ccc(OC)cc2OC)cc1 +COc1ccccc1N1CCN(CC2COC3(CCN(c4ccccn4)CC3)O2)CC1 +Cn1c(NC(C)(C)C)nc2c(-c3cc4c([nH]3)CNC4=O)cccc2c1=O +CC1CN(Cc2c[nH]nc2-c2ccc3c(c2)CNC(=O)O3)CCN1c1cccc(C(F)(F)F)c1 +OC1(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CCN(Cc2ccccc2)CC1 +O=C(NC1CCCC(CO)C1)C1CCN(c2nc3cc(Cl)c(-c4ccc(OC(F)(F)F)cc4)cc3o2)CC1 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2OC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1 +COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 +COC(=O)c1c(NC(=O)CC2SC(=N)NC2=O)sc(C)c1C +O=c1[nH]c(-c2ccc(F)cc2Cl)nc2c1oc1ccc(Br)cc12 +CCOc1cc(-c2c(C)noc2C)cc(C(O)c2ccccc2)c1 +O=C(Nc1ccc(Br)cc1)c1csc(Cc2c(Cl)cccc2Cl)n1 +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)N4CC5CC4CN5C)c4ccc(C)cc34)cc2)c1C +CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C4CC4)cn3)c2)c2cnc(N)nc21 +Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)c5cccc(Cl)c5)cc4)csc23)cn1 +CCCc1cc(C(=O)O)ccc1OCCCCCCc1cccc(O)c1O +COC(=O)COc1ccc(-c2cc3ccccc3[nH]2)cc1 +O=C(O)CCc1cc2cc(-c3cccc(OC4CCC4)c3)ccc2o1 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+Cn1c(-c2cccc(-c3ccccc3)c2)nnc1C1(c2ccc(Cl)cc2)CCC1 +O=C(c1ccc(-c2cccc(OC(F)(F)F)c2)cc1)N1CCN(c2ncccn2)CC1 +COc1cc(C(F)(F)F)ccc1-c1ccc(Cn2cncc2CN2CCN(c3cccc(Cl)c3)C(=O)C2)cc1 +COc1ccc(CC2CCOCC2)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(CN(C)C)cc2)c1 +O=C(CNC(=O)c1ccc(OCc2ccccc2)cc1)NC1CCCc2ccccc21 +CC1CC1C(=O)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)C1 +CC(Cc1ccccc1)(C(=O)NO)C(=O)NCCCCc1ccccc1 +CNc1nc(N)nc2nc(-c3c(F)cccc3C(F)(F)F)ccc12 +CNC(=O)c1nn(C)c2c1CCc1cnc(Nc3cc(N4CCN(C)CC4)ccc3OC)nc1-2 +CC1(O)CN(C(=O)N2CCC(C)(N3CCc4c(-c5cnc(N)nc5)nc(N5CCOCC5)nc43)C2)C1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1ccc(Cl)cc1 +O=C1CC(NC(=O)C2(C(=O)NNC(=O)c3cccc4ccccc34)Cc3ccccc3C2)C(O)O1 +Cc1ccc(S(=O)(=O)NC(CNC(=O)N2CCC3(CC2)CCN(c2ccc(C(=N)N)cc2)C3=O)C(=O)O)cc1 +COc1ccc(-n2c(-c3ccc(S(N)(=O)=O)cc3)coc2=O)cc1 +CS(=O)(=O)c1ccc(CNCC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +CN(C)CCNC(=O)c1cccn2c(=O)c3cc4ccccc4cc3nc12 +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2cc(C)c(C)c3ccccc23)c(Cl)c1 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+CCCCN1CC(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2NCCN(Cc3ccccc3)C2=O)CC1=O +O=C(Nc1ccc(C(F)(F)F)c(Cl)c1)N1CCC(F)(c2ncc(C(O)CO)cc2Cl)CC1 +O=C(c1ccc(OCCCN2CCC(NS(=O)(=O)c3cccc(Cl)c3)C2)cc1)C1CC1 +O=C(CN1CCCCC1)Nc1cccnc1C(=O)Nc1nccs1 +O=C(NCc1ccc(Cl)cc1Cl)c1ccc(=O)[nH]c1 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1sccc1CO)O2)C(C)=CC(C)(C)N3 +CCn1cc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2C)nc(N2CCOCC2)c1=O +COCCNc1cc(-n2c3c(c4cc(F)ccc42)C(=O)CCC3)ccc1C(N)=O +O=[N+]([O-])c1cccc(Nc2nc(N3CCN(CCO)CC3)nc3[nH]cnc23)c1 +CCOC(=O)CSCCNC(=O)c1sc(SC(C)C)c(C#N)c1-c1ccc(Cl)cc1 +CC(C)(C)c1cc(NC(=O)c2ccc(Cl)c(Nc3ncnc4cnc(N5CCOCC5)nc34)c2)no1 +CNC(=O)CNCCc1cccc(-c2cc3nc(NC)c4ncc(C)n4c3s2)c1 +Cc1ccc(COc2ccc3[nH]c(C4C(C(=O)O)C4(C)C)[n+](Cc4ccc(Br)cc4)c3c2)nc1 +COCC(=O)N1CCN(Cc2ccc3[nH]c(-c4cc5cc(-c6cn[nH]c6)ccc5[nH]c4=O)cc3c2)CC1 +CC(C)(Nc1nccc(-c2c[nH]c3ncccc23)n1)c1ccccc1 +CCOP(=O)(OCC)c1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(O)cc3)sc2c1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(Oc3ccccn3)cc2n1Cc1ccccn1 +COc1cccc(C#Cc2nn(C3CCN(C(=O)C=CCN(C)C)C3)c3ncnc(N)c23)c1 +CC1CN(c2nsc3ccccc23)CCN1CCCCN1C(=O)CC2(CCCC2)CC1=O +OCCCc1cc(F)c(OCc2c(-c3ccc(Cl)cc3F)nsc2C(F)(F)F)c(F)c1 +OC1CNC(CNC(COCOc2ccc(F)cc2)c2ccccc2)C1O +O=C(Nc1ccc(N(CCCl)CCCl)cc1)Nc1ccc2ncnc(Nc3ccc(F)cc3)c2c1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cc(F)ccc2F)CC1 +CCCC1(CC(=O)O)c2ccc(Cl)cc2-c2nc(O)c(O)nc21 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3c(C(=O)O)ccnc3c2)cc1 +CCCN(CCCCCCN(CCC)C1CCc2c(O)cccc2C1)C1CCc2c(O)cccc2C1 +Cc1cccc(-c2nc(C3CCN(Cc4ccc(-c5nc6nccn6cc5-c5ccc(F)cc5)cc4)CC3)n[nH]2)n1 +CC(C)c1ccccc1SC1=C(O)OC(CCCC(=O)N2CCSCC2)(c2ccccc2)CC1=O +CONC(=O)c1cc(Nc2ncnn3cc(-c4noc(C)n4)c(C(C)C)c23)c(F)cc1F +CCOC(=O)c1c(CN2CCN(CC#N)CC2)n(Cc2ccccc2)c2cc(Br)c(O)cc12 +Cn1cc(-c2ccc(C(=O)N3N=C(c4cccnc4)CC3c3c(O)cccc3F)s2)cn1 +Cc1cc(CNC(=O)c2sc3nc(C)c(Cl)c(C)c3c2N)ccn1 +CN(Cc1ccccc1)C(=O)C(Cc1ccccc1)NC(=O)C1CC(O)CN1C(=O)CCCc1ccccc1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CC4C(N)C4C3)cc2F)cn1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ncc(-c2ncccc2C(F)(F)F)cn1 +CC(CCC(=O)O)(NC(=O)NC(C)(CCC(=O)O)C(=O)O)C(=O)O +Cn1ccc2c3c(ccc21)CCN3C(=O)Nc1cccnc1 +C#Cc1ccc2nc(S)n3c2c1CN(CC=C(C)C)C(C)C3 +CCOc1ccc(C(=O)O)cc1NC(=O)C=Cc1ccc(-c2ccccc2)cc1 +CN(CC(=O)N1CCN(C(=O)c2ccccc2)CC1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +CC(C)CCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O +COc1cc(C=Cc2cc(-c3ccc(O)c(OC)c3)[nH]n2)ccc1O +CC(=O)N1CCN(c2nc(-c3ccc(Sc4ccccc4C(C)C)c(C(F)(F)F)c3)co2)CC1 +O=C(Cn1ccnc1[N+](=O)[O-])Nc1ccc(Oc2ccccc2)cc1 +NC(=O)n1cc(NC(=O)N2CC(F)CC2C(=O)NCc2cc(N3CCOCC3)cc(Cl)c2F)c2ccccc21 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCn1cccn1 +COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CC4CN(S(C)(=O)=O)CC4C3)cc12 +c1cc(CCc2cccc(-c3nn[nH]n3)c2)cc(OCc2ccc3ccccc3n2)c1 +COc1ccccc1N1CCN(CCC(O)c2ccc3ccccc3c2)CC1 +O=C(c1cc(Br)ccc1NS(=O)(=O)c1cccc2nsnc12)N1CCCCC1 +CCOC(=O)C(CC1CCCCC1)NC(=O)C(CC(C)C)NC(=O)Cc1ccccc1 +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OC[Si](C)(C)c2ccc(C)cc2)c1 +O=c1c(-c2ccc(OC(F)(F)F)cc2)cccn1C(CN1CCCC1)c1ccccc1 +CC(=O)Nc1cc(N)c(C#N)c(-c2ccccc2)n1 +CC(C)n1cc(-c2cnc(N)c(-c3ccc(C(=O)NC(CO)c4cccc(S(C)(=O)=O)c4)c(F)c3)c2)cn1 +Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc(C(=O)N5CCOCC5)cc4)cc3s2)S(C)(=O)=O)o1 +CCc1c(C(=O)C(N)=O)c2cc(OCCC(=O)O)ccn2c1Cc1ccccc1-c1ccccc1 +CCCCOc1ccc2c(c1)C(c1ccc3c(c1)OCO3)=C(C(=O)O)C(c1ccccc1OC)O2 +CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(-c3ccc(C(=O)O)s3)n2)cc1 +NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1 +COCCc1ccccc1-c1ccc(C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c(C)c1 +Cc1cc(C)c2c(c1)c(-c1ccccc1)c(-c1ccccc1)n2CC(O)Cn1cnc(-c2ccccc2)c1-c1ccccc1 +Cc1cc(C=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)no1 +COCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 +CC1CCCN1C1CCC(c2ccc(N3CCC4(CCOCC4)C3=O)cc2)C1 +Cc1ccc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C#N)CC3)n2)cc1F +CCCN1CCc2cccc3c2C1Cc1ccc(OS(=O)(=O)C(F)(F)F)c(OC)c1-3 +CC(C)(NP(=O)(OCC1C=CC(n2cnc3c(N)ncnc32)C1)Oc1ccccc1)C(=O)O +CN(C)CC1CCc2cc(NC(=O)c3ccc(-c4ccccc4)cc3)ccc2C1 +Nc1nc2c(Cc3ccccn3)c[nH]c2c(=O)[nH]1 +CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)C(=O)CCCCC(CCSC(=O)CN)SC(=O)CN 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+O=C(C1CCN(c2ccncc2)CC1)N1CCC(CNS(=O)(=O)C=Cc2ccc(Br)s2)C1 +O=[N+]([O-])c1cc([N+](=O)[O-])c(-c2cc[nH]n2)s1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)ncnc2cc1OCCN1CCC(=O)CC1 +COc1cc(Nc2ncc3ccn(-c4cccc(CCC#N)c4)c3n2)cc(OC)c1OC +CCc1cc(Nc2cc(=O)n(CCCO)c(=O)[nH]2)ccc1C +Cc1c(F)cccc1Cc1c(C(=O)N2CCNCC2)c2ncccc2n1-c1ccccc1 +COC(=O)C(N)CSC(c1ccccc1)(c1ccccc1)c1ccc(OC)cc1 +CCCCCCCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +NCc1cc(Cc2c(-c3ccc(OCCN4CCCC4)cc3)sc3cc(O)ccc23)ccc1CN1CCCC1 +Nc1nc2ccccc2n2c(=O)c(-c3ccc(F)cc3)nn12 +Cc1[nH]c(C=C2C(=O)Nc3ccccc32)c(C)c1CCC(=O)O +CC(=O)N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +Cc1ccc(F)c(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1Cl +CC(C)(C)C1CCN(C(=O)n2ncc(C(O)(c3ccccc3)c3ccccc3)n2)CC1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cnn(CC4CCCOC4)c3)c(C(=O)O)n1)CC2 +CNc1nc(NC2(C#N)CCCC(C)C2)nc(-n2cncn2)n1 +CN(Cc1ccccn1)C(=O)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)CCC4 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)NCc3cccnc3)[nH]c12 +O=C(Nc1ccccc1)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccccc1 +Cn1nc2c(c1-c1ccccc1)-c1nc(Nc3ccn(CCN4CCCC4)n3)ncc1CC2 +Cc1cc(-c2nc(-c3ccc(OCC4COC(=O)N4)c(C)n3)no2)cc(CC(C)C)n1 +COc1ccc(C2=NN(CCn3ccnc3)C(=O)C3CCCCC23)cc1OC +NS(=O)(=O)OCC1OC(OCC2C(CO)OC(O)C(O)C2O)C(O)C(O)C1O +Cn1cc(-c2cn(-c3ccnc4c3c(C(F)(F)F)nn4-c3ccc(C(N)=O)cc3N)cn2)cn1 +COc1ccc2c(c1)cc(-c1ccccc1)n2Cc1csc(C(=O)O)n1 +COc1cc2c(c(OC)c1)CN1CCc3cc(OC)c(O)cc3C1C2 +Nc1nc(-c2cccc(CN3CCC(c4ccccc4)CC3)c2)cc2nc(-c3ccco3)nn12 +CS(=O)(=O)c1ccc(C(=O)N2CCN(c3ccc(OC4CCN(C5CCCC5)CC4)cc3)C(=O)C2)cc1 +CC(C)N1CC(C(=O)N2CCN(c3ccccc3Cn3cnnc3)CC2)C(c2ccc(Cl)cc2)C1 +CSc1ccc(-c2ccc(C(=O)CC(=O)C(=O)O)cc2)cc1 +COc1cccc(F)c1C1CC(C)C(=O)N1Cc1cccc(-c2nc(Cl)cs2)c1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ccc(OCC(F)F)cn3)cs2)CO1 +CC1(N)CCC(Nc2c(C(N)=O)cnn3cc(-c4ccc(Cl)cc4)cc23)C1(C)C +CC(C)(Cc1ccc2ccccc2c1)NCC(O)C1CCCN1Cc1cccc(C#N)c1 +O=C(c1nn(C2CCCN(CCN3CCOCC3)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +NC1=NCCCN1Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 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+NC(=O)n1cc(NC(=O)N2CCC(N)C2C(=O)NC(c2cccc(Cl)c2F)C(F)(F)F)c2ccccc21 +CCCCN(Cc1cncn1Cc1ccc(C#N)cc1)c1ccc(Oc2ccccc2)cc1 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)c2ccccc2C)cc1 +CCCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21 +NC1CCCC(c2ccncc2NC(=O)c2ccc(F)c(-c3cc(F)ccc3F)n2)C1 +CC(C)(C)C(=O)Nc1ccc(N=Nc2ccccc2)cc1 +NC(CC(=O)N1CCC2C(CCc3nnc(-c4ccccn4)n32)C1)Cc1cc(F)c(F)cc1F +CC(C)(C)c1ccc(OS(N)(=O)=O)c(OS(N)(=O)=O)c1 +COCCc1nccn1CC1CC(c2ccccc2)(c2ccccc2)C(=O)O1 +CCCCCCCCCCCCCCCCCCN1CCN(C(=O)Nc2ccc(Cc3noc(=O)[nH]3)cc2)CC1 +N#Cc1ccccc1CSc1nnc2c3ccccc3n(C(=O)c3ccc(F)cc3)c2n1 +O=C1CCC2(O)C3CC4=C(CCCC4)C2(CCN3CC2CC2)C1 +CC(Nc1ncnc2[nH]cnc12)c1nc2ccccc2c(=O)n1-c1cccc(F)c1 +CC(=O)Nc1ccc2c3c(n(CCCCl)c(=O)c2c1)-c1cc2c(cc1C3=O)OCO2 +CCOC(=O)C1(Cc2ccccc2)CCCc2cnc3c(-c4ccc(C(F)(F)F)cc4)cnn3c21 +CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)cc3)CC2)nc1C(F)(F)F +O=C(CO)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)Cc1c(F)cccc1F 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+CCN(C(=O)CO)C1CN(C(=NC#N)Nc2cccc(OC(F)F)n2)N=C1c1ccc(Cl)c(Cl)c1 +O=C(CNC(=O)C1(CS)CCc2ccccc2C1)OCc1ccccc1 +CCOC(=O)CN1Cc2cc(OCCCC(=O)N(C)C3CCCCC3)ccc2N=C1N +O=C(NCC1(CO)CCCCC1)c1nc2c(-c3ccccc3)cccc2[nH]1 +CC12Nc3ccccc3C1(O)CCN2Cc1ccc(C=CC(=O)NO)cc1 +O=C(NCc1cccc(OCCOc2nc[nH]n2)c1)c1nc2scc(-c3ccccc3F)c2c(=O)[nH]1 +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 +O=C1Nc2c(Cl)cccc2C1=CNCCCNc1ccnc2cc(Cl)ccc12 +CN1CCCC(NC(=O)c2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c2)C1 +COc1cc(OC)cc(N(CCO)c2ccc3ncc(-c4cnn(C5CCN(C(=O)OC(C)(C)C)CC5)c4)nc3c2)c1 +O=C(O)CC(Cc1ccc(OCCCNc2ccccn2)cc1)c1ccccc1 +N#Cc1ccc(NC(=S)NC(=N)Cc2ccc(Cl)cc2)cc1 +O=C(NO)C(CNS(=O)(=O)c1ccc(OCc2ccc3ccccc3c2)cc1)N1CCCCC1 +CS(=O)(=O)Nc1ccc(-c2coc3cc(C#CC4CN(C(=O)C5CC5)C4)ccc3c2=O)cc1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2ccccc2-c2ccon2)n1 +CCC(=O)Oc1ccc(-c2nc(-c3cccnc3)no2)cc1 +CC(=O)N1CCCN(C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +Cc1csc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)n(C)c2=O)n1 +c1cc(C[n+]2ccc(N3CCCC3)cc2)ccc1CCCc1ccc(C[n+]2ccc(N3CCCC3)cc2)cc1 +CN(C)CC(=O)Nc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 +CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NCCc3ccccc3)CC2)nc1C(F)(F)F +CCc1nc(-c2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)cc2)co1 +Cc1cc(CC2CC2)cc(C)c1NC(=O)Nc1cc(F)ccc1C(=O)NC(C(=O)O)C(C)OC(C)(C)C +CN(C)CCCN(C(=O)c1ccc2c(c1)sc1c(O)nc3ccccc3c12)c1ccccc1 +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1cccc(OC(F)(F)F)c1 +O=C(c1cccc(O)c1)c1ccc(-c2cccc(NS(=O)(=O)c3ccc([N+](=O)[O-])cc3)c2)s1 +Cn1c(=O)c(-c2c(F)cccc2F)cc2c(N)nc(Nc3ccccc3)nc21 +Clc1cccc(Nc2[nH]nc3ncnc(NCc4ccccc4)c23)c1 +Cc1cccc(C(CC2CCCCC2)Nc2nc3ccccc3o2)c1 +CN(C(=O)C1CC1)c1ccc2c(c1)nc(NC(=O)c1ccc(C#N)cc1)n2CCC(N)=O +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)C3CCC3)c3ccccc32)CC1 +Nc1nc(N)c2c(n1)CCC2CCc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +O=C(c1nn(-c2ccccc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1)N1CCCCC1 +Cc1cc(-c2nc3cnc(N4CCOCC4C)nc3n2C(C)c2ccccc2)cn(C)c1=O +CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3ccc(Br)cc3F)c2c1 +O=C(c1cccc(C(F)(F)F)c1F)N1CCc2c(nnn2-c2ccccn2)C1 +CC1CC2CC(c3cccc(O)c3)(CCN2CCc2ccccc2)C1 +COc1ccc(C(Cc2ccncc2)c2cccc(F)c2)cc1OC1CCCC1 +CCN1C(=O)Cn2c1nc1nc(N3CCCC(N)C3)n(Cc3cc(F)ccc3C#N)c1c2=O +Cc1ccccc1NS(=O)(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COc1ccccc1C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1 +CC(C)c1cc(-c2cccc(C=C(C(=O)O)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 +O=C(Nc1ccc(-c2ccccc2)cc1)Nc1ccc2c(c1)NC(=O)C2=Cc1ccc[nH]1 +COc1cc(C=Cc2ccc(CCC(=O)C(C)(C)C)cc2)cc(OC)c1 +CN1C2CCC1CC(OC(c1ccc(F)cc1)c1cccc(Br)c1)C2 +COc1cc(C=Cc2ccc(N(C)C)cc2)cc(OC)c1OC +CCOC(=O)c1ccc2ncnc(NCc3ccc4c(c3)OCO4)c2c1 +CN(C(=O)C1=Cc2cc(Br)ccc2S1(=O)=O)c1ccccc1 +CNC(=O)c1ccc(-c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C)cc3)n2)cc1 +Cc1c(Oc2cnc(C(=O)N3CCC(C)(O)C3)cn2)ccc2c1B(O)OC2 +CC(C)Nc1nc(-c2ccc(N3CCCC3)c(S(C)(=O)=O)c2)cc2ncn(C)c(=O)c12 +O=C1C2C3CCC(C4CC43)C2C(=O)N1CCCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +O=C(O)CON=Cc1nc2ccccc2n1C1CC2CCCC(C1)N2C1CC2CCCC(C2)C1 +CCOc1ccc(-n2c(C(C)N(Cc3cccnc3)C(=O)Cc3ccc(S(C)(=O)=O)cc3)nc3ccccc3c2=O)cc1 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+S=C(Nc1ccc(Cl)cc1)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +O=C(c1ccc(Nc2nccc(-c3cc4ccccc4s3)n2)cc1)N1CCC(N2CCCC2)CC1 +N#CC1CCN(C(=O)OCC2CC2)CC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +Cc1cn2nc(C3CCCCN3C(=O)c3cc(Cl)ccc3NS(C)(=O)=O)cc2nc1N1CCC(O)C1 +O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1nc(N2CCNCC2)nc2ccccc12 +CC(C)C1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)CC1 +N=C(N)c1ccc2[nH]cc(CC(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cn3)c2c1 +C#CC(=O)Nc1cc(-c2cnc3[nH]cc(C)c3c2)ccc1F +CC(C)c1cc(Nc2cc(OC3CCN(C)C3)nc(NCc3cc(C(C)C)no3)n2)[nH]n1 +N#CC(c1cccnc1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1 +COCCN1CCCC1Cc1c[nH]c2ccc(-n3cnc4cc(C#N)ccc43)cc12 +Fc1cccc2nc(N3CCN(Cc4cccs4)CC3)c3cccn3c12 +CC(C)(C)C(=O)NCCC1(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)CCCC1 +Cc1cc(-c2nc(C(c3ccc(F)cc3)c3ccc(F)cc3)sc2CC(=O)O)cnc1N +O=C(O)c1ccc2nc(C(=O)COc3ccc(SCCCCCc4ccccc4)cc3)sc2c1 +CC(C)n1ncc2c(C(=O)Nc3ncccn3)cc(-c3cccs3)nc21 +COCC1CCCN1c1cccc(Nc2cc(-c3ccccc3)nn3ccnc23)n1 +CN(C)CCCNCc1cccc(-c2cc(NCCN3CCOCC3)c3ccccc3n2)c1 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+CN1CCc2c3c(n(-c4ccc5c(c4)CCNC5=O)c2C1)CC(C)(C)CC3=O +COc1cc(-c2ccc3ncnc(Nc4cc(O)c(Cl)cc4Cl)c3c2)ccc1O +COc1cc(C(=O)c2csc(-c3ccccc3)n2)cc(OC)c1OCCN +CC1(C(=O)NC(CC(=O)O)c2ccc(-c3c(O)cccc3O)cc2)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +O=C(CSc1nnc(-c2ccc(O)cc2)[nH]1)Nc1ccccc1Cl +COC(=O)C=Cc1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(Cl)c(Cl)c1 +CCNc1nc2cnccc2nc1N1CCC(Oc2ccc(OC)cc2F)CC1 +Cc1cc(C=CC#N)cc(C)c1Nc1ccc(F)c(Nc2ccc(F)cc2)n1 +CCOC(=O)c1cc2c(n1C)-c1nc(Nc3ccccc3)ncc1CCC2 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(Cc1ccccc1)C(C)(O)C(=O)NO +N#Cc1ccc(-c2ccc(C(CCNC3CCCC3)CNC(=O)Nc3cc(Cl)cc(Cl)c3)cc2)cc1 +O=C(c1ccc(Cl)cc1C(F)(F)F)N1CCn2c(nnc2-c2cnccn2)C1 +CN1CCN(C23CCNC(C(c4ccccc4)C2)C(c2ccccc2)C3)CC1 +O=C1C(=Cc2c[nH]c3ccccc23)Oc2c1ccc(O)c2CN1CCCNCC1 +CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc(-c4ccc(CO)cc4)cc3)cc12 +CCCCCCC=C1CC(CO)(COC(=O)c2ccccc2C)OC1=O +CN(C)CCCn1cnnc1-c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)cc3Cl)cc2F)ccn1 +COc1cc(C=NNC(=O)C(OC)c2ccc(N3CCOCC3)cc2)cc(OC)c1Br +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1cccc2ccccc12 +Cc1nc(O)c2cc(-c3ccc4c(c3)OCO4)c(C(C)C)cc2n1 +O=C(NS(=O)(=O)NCC1OC(n2cnc3c(NC4CC4)ncnc32)C(O)C1O)c1ccccc1O +CC1CCC(Cn2c(N3CCOC4CCCC43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cc(Cl)cnc4OCCO)c32)CC1 +COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(C(=O)c2ccc(Cl)cc2)CC3)c1 +OCCCCCN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +O=C(NC1CN2CCC1CC2)c1ccc2cc[nH]c2c1 +CC(NC(=O)Nc1cc2[nH]nc(C#N)c2cn1)c1ccccc1 +Cc1ccc(CNCC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)o1 +CN(Cc1ccc(Cl)cc1)C(=O)n1cnc(S(=O)(=O)C2CC3CCC2C3)n1 +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=NC#N)c(F)c2)cn1C(C)C +OC(c1ccc(Cl)cc1)(c1cccnc1)c1ccc(F)cc1F +CC(C)c1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 +Cc1cc(C)c2oc(Nc3ccc(-c4cccc(C(N)=O)c4N)cc3F)nc2c1 +CCNC(=O)C1OC(n2cnc3c(N)nc(C#Cc4ccc(C(C)=O)cc4)nc32)C(O)C1O +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4cccc(Cl)n4)c3)ncnc12 +COc1cccc(-c2cc3[nH]c4ccc(O)cc4c3c3c2C(=O)NC3=O)c1 +CCC(C)C(=O)NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1 +N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccsc1 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+O=C(NCC1CCOCC1)c1cnc(Nc2cccc(Cl)c2)cc1C1CC1 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cccc(OC(F)(F)F)c3)c(F)c2)CC1 +Cc1cc(SCc2csnc2-c2ccc(C(F)(F)F)cc2)ccc1OCC(=O)O +O=C(NC(C(=O)N1CCCCC1)=C(Br)c1ccccc1)c1ccc(Cl)cc1 +CC(C)(C)c1ccc(-n2nc(-c3ccncc3)cc2CCCCC(=O)NC(CC(N)=O)Cc2ccccc2)cc1 +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCCC4)c23)c1 +CN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(C(C)C)cc1 +O=C1NC(Nc2ccc3c(c2)OCO3)=NC1=Cc1ccc2c(c1)OCO2 +CN1C(=O)NCc2c(NC(=O)NC3CC(C)(CF)Oc4cc(Cl)ccc43)cccc21 +COc1ccc(C=NN(C)c2ncnc3ccccc23)cc1OC +CN1C(=O)CCc2cc(-c3cccnc3)c(OCc3ccccc3)cc21 +Cn1cnc(S(=O)(=O)N2CC3C(C2)C3(CNC(=O)c2ccc(Cl)cc2)CC2CC2)c1 +COc1ccc(C2(Cc3ccncc3)CCN(S(=O)(=O)c3ccc(C)cc3)C2=O)cc1OC1CCCC1 +O=C1CCc2ccc(OCCCCN3CCN(c4ccc(O)c5[nH]c(=O)ccc45)CC3)cc2N1 +CCn1c2ccccc2c2cc(NS(=O)(=O)c3c(OC)ccnc3OC)ccc21 +c1cc(-c2cnc3[nH]cc(-c4cn[nH]c4)c3n2)ccn1 +CCOc1ccccc1N1CCN(CC(O)CN2C(=O)NC(=Cc3ccc(Cl)cc3)C2=O)CC1 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+COc1cc2c(NC3CCCCC3)c(C(N)=O)cnc2cc1-c1c(C)noc1C +ON=c1cc(-c2cc3cccn3cn2)oc2ccc(OCCCc3cccnc3)cc12 +COc1cc(-c2ncc(-c3ccc(N4CCNCC4)nc3)n3cc(C=Cc4ccc5ccccc5n4)nc23)ccn1 +CC(C)N(CCN1CCOCC1)C(=O)C(C)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O +O=C(NC(Cc1c[nH]c2ccccc12)C1CN=C(CCc2ccccc2)S1)OC1C2CC3CC(C2)CC1C3 +CC1(C)CC=C(c2cc(C(O)C(=O)O)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +CC(=O)OC1(C)c2ccccc2-c2c1c(-n1ccnc1)nc1ccc(Br)cc21 +CC1CCCCN1c1cccc(-c2c[nH]c3ccc(-c4nnc(N)s4)cc23)n1 +CCC1(C)Cc2cccc(OCCNCc3cccc(C4=CCCC4)c3)c2O1 +COc1ccccc1N1CCN(CCCCc2ccc3nc(O)sc3c2)CC1 +CCCOc1ccc(NCc2cnc3nc(N)nc(N)c3c2C)cc1OC +CN(CCCN)C(=O)N1CC(c2cc(F)ccc2F)=CC1c1ccccc1 +NC(=O)c1ccc(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)cc1 +CCOc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cc1Cl +CC(C)CN(Cc1ccc(N2CCC(N(C)C)C2)cc1)S(=O)(=O)Cc1ccccc1 +O=C(Nc1ccc(N2CCOCC2)cc1)C(=O)c1c[nH]c2c(Cl)cccc12 +CCC(Sc1nc(-c2cccc(OC)c2)c(C#N)c(=O)[nH]1)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 +CCCCCCSc1cc(C)c(C(=O)CCN2CCN(C(C)=O)CC2)c(C)c1 +Fc1ccc(C23CCN(CC2)Cc2cc(Oc4ccc(C(F)(F)F)nn4)ccc23)cc1 +Cc1nc2c3ccccc3nc(SCc3ccc4ccccc4n3)n2n1 +CC1CCC2C(C)C(OC(=O)CCN3CCN(C)CC3)OC3OC4(C)CCC1C32OO4 +CCCCc1nnc(S(C)(=O)=O)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +CC(NC(=O)C1(N)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(F)cc1 +O=C(c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1)N1CC(F)CC1c1cc(F)ccc1F +Cn1c(NC(C)(C)C)nc2c(-c3cc4c([nH]3)CCNC4=O)cccc2c1=O +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1-c1ccc(=O)n(C)c1 +COc1ccc(CCN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1 +Cc1cc(Oc2nccc3[nH]ccc23)ccc1-c1c(C)n[nH]c(=O)c1C +CCCCCCCCCCc1ccc2c(c1)N(C)C(C(C)C)C(=O)NC(CO)C2 +COc1ccccc1CCc1nnc(-c2ccc3[nH]cnc3c2)s1 +Fc1ccc(Cn2c(C3CCCNC3)nc3ccccc32)cc1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1ccc(CN2CCC(F)(F)CC2)c(F)c1 +COc1ccc(-c2nc(N)c(CN)c(-c3ccc(Cl)cc3Cl)n2)cc1 +N#Cc1cc(COc2ccc3[nH]c4c(c3c2)CCC4CC(=O)O)cc(OC(F)(F)F)c1 +Cc1ccc2[nH]c(-c3ccc(S(N)(=O)=O)cc3)c(-c3ccccc3)c2c1 +NCCN1CCCC(NC(=O)N2CCC3C2C(=O)N3S(=O)(=O)O)CC1 +Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(C(F)(F)F)c2)c(=O)c2ccc(CO)cc21 +O=c1cc(-c2ccncc2)[nH]n1-c1ccc([N+](=O)[O-])cc1 +Cc1cc2c(o1)-c1c(c3ccccc3c(=O)n1CCCN1CCC(N3CCOCC3)CC1)C(=O)C2=O +Cc1cc(NCc2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)on1 +COc1nc(N2CC3C(=O)N(C)C(N)=NC3(c3c(F)cc(F)c(F)c3F)C2)nc(C)c1F +Cc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1ccccc1 +Cc1c(CN2CCC(C(=O)NC(C)(C)C)CC2)cccc1NC(=O)c1ccc(F)cc1 +Cc1ccccc1CNc1c2c(nc3ccccc13)CCCC2O +CC(=O)Nc1cc(-c2cccc(OC3CCN(C)C3)c2)nc(-n2nc(C)cc2C)n1 +O=C(Nc1cccc(C(=O)c2ccc3c(C=Nn4cnnc4)n[nH]c3c2)c1)c1ccccc1 +CCCNc1cc2[nH]c(=O)cc(C(F)(F)F)c2cc1C +COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(C)(F)F)cc1 +CCN1C(=Cc2sc3ccc(O)cc3[n+]2CC)C=Cc2ccccc21 +CCN1CCC(NC(=O)c2ccc(Nc3ncc4c(n3)-c3c(nn(C)c3-c3ccccc3)CC4)c(OC)c2)CC1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)Oc1ccc(F)c2ccccc12 +CNc1nn2c(C)c(CCN)c(C)nc2c1S(=O)(=O)c1ccccc1 +N#Cc1c[nH]c(C(=O)Nc2ccc(-c3nnn[nH]3)cc2C2=CCCCC2)n1 +O=C(CCCN1CCN(CC(=O)c2ccccc2)CC1)NC1c2ccccc2CSc2ccccc21 +Cc1nc2ccccc2n1Cc1ccc(CNC(=O)C(O)C(O)C(=O)N2CCCC2c2ccccn2)s1 +Cc1cc(NC(=O)C(=O)c2cn(Cc3cc(-c4ccccc4)no3)c3ccccc23)sn1 +Nc1ccc(OCC(O)CNCCc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)cn1 +O=C(NC1CCCCC1)N1CCN(C(c2ccc(Cl)cc2)c2ccccc2C(F)(F)F)CC1 +O=C(CN1CCCC(c2nc3cc(Cl)c(Cl)cc3[nH]2)C1)c1cc(Cl)cc(Cl)c1 +CCOc1ccc(C(C)=O)cc1NC(=O)c1cc(C(=O)O)cc(-c2ccoc2)c1 +CCOc1ccc(-c2c3c(c(O)c4ncccc24)C(=O)N(Cc2ccc(F)cc2)C3)cc1 +CC(C)CN(NC(=O)c1cncc(-c2ccc(CN3CCN(C)CC3)cc2)c1)c1nc(C#N)ncc1Br +COc1ccc(CNC(=O)CCC(=O)N2CC3CC(C2)c2cccc(=O)n2C3)cc1 +CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccco4)nc23)CC1 +CC(=O)Nc1ccc(-c2nc(-c3nnc(Cc4ccc(F)cc4)o3)c(O)c3ncccc23)cc1 +O=C1CC(c2ccccc2)Cc2c1c1c(n2CCc2ccccc2)-c2ccccc2C1=O +O=C(O)COc1ccc(CCN(C(=O)c2ccccc2)c2ccc(Cl)cc2)cc1 +CC(C)Cc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1 +CC(COc1c(-c2ccccc2)c(O)nc2cc(Cl)ccc12)=NO +CCc1nc(N)nc(N)c1C#CC(C)c1cnc(-c2ccccc2)nc1 +FC(F)(F)c1cccnc1N1CCc2nc(C3CC3)nc(Nc3ccc(Cl)cc3)c2CC1 +CCn1cc(-c2cccc(-c3cnc(N)c(C(=O)NC4C5CC6CC4CC(O)(C6)C5)n3)c2)cn1 +COCC1CC2CCC(C1)N2c1nc(C#N)nc2scc(-c3ccccc3OC)c12 +CCCCCOc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +CC(O)c1cc(C(=O)NC(C)c2ccc(F)cc2)ccc1-c1cn[nH]c1 +O=C(Nc1nc2cc(CN3CCCCC3)ccc2n1C1CCC(CO)CC1)c1cccc(C(F)(F)F)c1 +CCCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(ccc3ncccc23)C1 +C#CCN(Cc1ccccc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +CN1CC=CCOCc2cccc(c2)-c2ccnc(n2)Nc2cccc(c2)C1 +CCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)cc1 +CC(NC(=O)c1ccon1)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 +CC(=O)NCC1CCCc2c1c1cc(OC(F)(F)F)ccc1n2C +O=C(Cn1ccc(C(F)(F)F)n1)N1CCN(c2scnc2-c2nc3ccccc3[nH]2)CC1 +COc1ccccc1N1CCN(CC(O)CCNC(=O)c2ccc(-c3ccccn3)cc2)CC1 +CCCSc1nc(N2CCOCC2)ncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 +COCC(C)NCc1csc(NC(=O)c2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(-c3ncccc3C)c2)n1 +COc1cc(-c2ccccc2C)ccc1C(C)C#Cc1c(C)nc(N)nc1N +OC1c2ccc(F)cc2CC1N1CCN(c2cccc3c2OCCO3)CC1 +COc1ccccc1OCCN1CCN(c2ccc(=O)n(CCCCCCN3CCN(c4ccccc4Cl)CC3)n2)CC1 +COc1cc(C=CC(=O)c2ccc(OCCOC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)cc(OC)c1OC +N#Cc1ccc(Cn2cncc2CN2CCCN(C(=O)c3ccccc3F)CC2)cc1 +CN(C)C1CCN(CC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)CC1 +Cc1ccc(-c2ccc(S(=O)(=O)Nc3ccc4c(c3)CCN(C)CC4)cc2)s1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4ncc(=O)[nH]c34)cc2)cc1 +O=C1NC(c2cccc([N+](=O)[O-])c2)=CCN1c1ccccc1O +CS(=O)(=O)c1ccc(COc2ccc3c(c2)c(C#N)cn3-c2ccc(C(=O)O)cc2)cc1 +CCC(Nc1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)c1ccc(S(C)(=O)=O)cc1 +CCN(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccn1 +Cc1nc(-c2ccc(N3C(=O)C(=O)C(S(=O)(=O)c4ccccc4)C3C3CCCCC3)cc2)no1 +O=c1c2ccccc2oc2ccc(OC3CN4CCC3CC4)cc12 +CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(CCI)C1CCC(CO)CC21 +COC1CN(C(=O)c2ccc(Nc3cc4c(-c5cnn(C)c5)cccc4cn3)c(Cl)c2)C1 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(C(F)(F)F)ccc1NC(C)C +CN(CCCNc1ccnc2cc(Cl)ccc12)Cc1ccc(-c2ccc(F)cc2)s1 +Cn1nc(C(C)(C)C)cc1C(=O)NC(Cc1cccc(-c2nnc(CCN)o2)c1)C(=O)NCC#N +CC(C)C(NC(=O)C(CC#Cc1ccccc1F)NCP(=O)(O)O)C(=O)O +CS(=O)(=O)c1ccc(-c2sc3ncnn3c2-c2ccc(F)cc2)cc1 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1ncnc2nn3ccccc3c12 +CC(C)(Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 +O=C(NC1C2CC3CC(C2)CC1C3)C1SCCN1S(=O)(=O)c1ccccc1F +COC(=O)C(Cc1ccc(O)cc1)NC(=O)c1cc(C(=O)O)c2cc(-c3ccc(Cl)cc3)ccc2n1 +O=S(=O)(c1cc(Cl)cc(Cl)c1O)N1CCCC1c1nn[nH]n1 +N=C(N)c1cccc(OCC(NC(=O)c2ccc(-c3ccccc3S(N)(=O)=O)cc2)c2ccccc2)c1 +Cc1c(-c2cn(C3CCC3)cn2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +c1ccc(-n2cc(COCc3ccc(-c4nnc5n4-c4cccnc4Nc4ccccc4-5)cc3)nn2)cc1 +CCCC(CNC(=O)c1nc(Cl)c(N)nc1N)[N+](C)(C)C +COc1cc(C(=O)NC(CN)Cc2ccccc2)ccc1-c1cn[nH]c1 +CCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccccc3)cc2s1 +COc1cc2c(Oc3ccc(NC(=O)c4cn(-c5ccc(F)c(F)c5)nn4)cc3F)ccnc2cc1OCCCN1CCCCC1 +CN1CCc2ccc(Cc3ccc(O)c4ccccc34)c3c2C1Cc1ccc(O)c(O)c1-3 +COc1cc(C(=CC#N)c2ccc3c(c2)c(C#N)cn3C)cc(OC)c1OC +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1cc(CCN2CCCC2)cnc1C +O=C1N(Cc2ccc3[nH]ncc3c2)C(CCc2ccccc2)C(O)C(Cc2ccccc2)N1Cc1ccc2[nH]ncc2c1 +CN1CCN(c2nc(-c3ccc(Br)cc3)nnc2-c2ccccc2)CC1 +Cc1cc(C)c2c3c1C1C=CCC1CN3C(C(=O)O)C1CC=CC21 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+O=C(NC(Cc1ccccc1)C(=O)COCC(=O)N1CCCC1C(=O)O)c1ccccc1 +FC(F)(F)c1ccc(-c2nnc3ccc(NC4CCCCC4)nn23)cc1 +CCN(Cc1ccccc1)Cc1ccc(C(=O)c2ccc(OC)c(OC)c2)cc1 +Nc1ncnn2c(CN3CCNCC3)cc(-c3ccc(CO)cc3)c12 +Oc1nc(CNC2CCC(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2c2ccccc2)c[nH]1 +O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(Cl)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cc2C#N)c(F)c1 +CN(C)Cc1cccc2[nH]c(-c3nc(CCc4ccc(Cl)cc4)no3)cc12 +COc1cc(OC)cc(-c2cc3cnc(N(CCCOCc4ccccc4)C(C)=O)cc3nc2NC(=O)NC(C)(C)C)c1 +N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCCCCOc3cc4c(cc3C(=O)N2)CCCC4)CC1 +COc1ccc(CN)cc1NC(=O)CN1CCCCC(NC(=O)c2ccc(-c3ccccc3)cc2)C1=O +c1ccc(Oc2nc3ncnc-3c(NC3CCCCC3)[nH]2)cc1 +COC(=O)c1nn(C(=O)c2ccsc2)c2ccccc12 +O=S(=O)(c1ccc(Cl)c(Cl)c1)N1CCCc2ccc(Oc3cc(-c4nc(C5CC5)no4)cc(Cl)n3)cc21 +COc1c(C=Cc2ccc(NS(C)(=O)=O)c(F)c2)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C +CC(NC(=O)Cc1ccoc1)C(=O)NC1C(=O)N(C)N(C(C)C)C(=O)c2ccccc21 +O=C1c2c(F)cc(F)cc2CCC12CCN(CCc1ccccc1)CC2 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+N#Cc1cccc(-c2ccc(CN(CCN3CCCC3)C(=O)Nc3ccc(F)c(C(F)(F)F)c3)cc2)c1 +NC(Cc1ccccc1)c1nc2ccc(-c3cn[nH]c3)cc2c(=O)[nH]1 +COc1ccc(NC(=O)Nc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)cc1 +CCCCCc1ccc(S(=O)(=O)NCCc2c(-c3cccc(C)c3)[nH]c3ccccc23)cc1 +O=C(NCc1cc(F)c(N2C3CCCC2CC3)c(F)c1)Nc1cccc2[nH]ncc12 +COc1ccccc1N1CCN(C(C)CN2C(=O)NC3c4ccccc4N(C)C3C2=O)CC1 +Cc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Cl)cc2)c1 +CCN1CCC(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)C1 +CC(C)N1CCN(CCN2CCC(c3cn(-c4ccc(F)cc4)c4cc(F)ccc34)CC2)C1=O +Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2)c(C)c1CC(=O)O +Nc1nc(-c2cccs2)nc2cn(-c3ccccc3)nc12 +COc1ccccc1N1CCN(CCCNC(=O)CN2CCCCC2=O)CC1 +CC(=O)c1cnc2ccc(-c3ccc4nc[nH]c4c3)cc2c1Nc1cnn(C2CCN(C)CC2)c1 +CCC1([N+]23CCC(CC2)C(OC(=O)C2(O)c4ccccc4-c4ccccc42)C3)c2ccsc21 +CCCCC1CCc2cc(C(=O)C(C)C)cc3c(CCN4CCN(c5cc(C)ccn5)CC4)c(C)n1c23 +Cc1cccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)n1 +Cc1nc(-c2ccc(C)s2)c(-c2ccc(S(N)(=O)=O)cc2)o1 +O=C1C(=Cc2ccncc2)C(c2ccccc2)n2cccc21 +Cc1nc2ccc(F)cc2n1C1CC2CCC(C1)N2CCC(NC(=O)c1ccc[n+]([O-])c1)c1cccc(F)c1 +COc1cc(C=CC(=O)Nc2ccccc2)ccc1OCCCCCCN1CCCCC1 +c1nc(NC2CCCCCC2)c2cc(OCCN3CCOCC3)ncc2n1 +CC(=C1C(=O)Nc2ccc(Cl)cc21)c1ccc(-c2cccc(C(=O)N3CCCN(C)CC3)c2)o1 +NCC1(O)CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1 +CC(C)CC1CN(c2cccc(C(=O)c3cccnc3N)n2)CCN1 +COc1cc(-c2cnc3cccc(-c4ccc(CC(=O)N5CCOCC5)cc4)c3n2)cc(OC)c1OC +O=C(c1ccccc1-c1ccc(F)cc1)N1CC2CN(c3cnc4ccccc4n3)CC2C1 +CCSC(=S)SCC(=O)c1ccc(CC(=O)NCc2ccccc2)s1 +O=S(=O)(c1ccc(OC(F)F)cc1)c1cc(Cl)c2oc3c(c2c1)CNCC3 +O=C1c2c(c(N3CCCS3(=O)=O)c3cccnc3c2O)CN1Cc1ccc(F)cc1 +CC(Nc1nccn2c(-c3ccc(O)cc3)cnc12)c1ccc(S(N)(=O)=O)cc1 +Clc1cccc(Cl)c1OCCNCCOc1ccccc1OCc1ccccc1 +CNc1ccc(C2Cc3c(cccc3C(F)(F)F)N(CCN(C)C)C(=O)C2C)cc1 +CCc1cc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)c(C(=O)O)c2)c2c(n1)CCCC2 +C=CCC(O)C(NC(C)=O)C1NC(C(=O)O)CC1C=CC +O=C(c1ccc(Cl)cc1Cl)N1CCn2c(nnc2-c2cnccn2)C1 +CC1(F)CCCC1Nc1c(C(N)=O)cnn2cc(-c3cncc4ccccc34)cc12 +C=CCNC(=O)c1c[n+]([O-])c2c(cnn2CCCCC)c1N +COCCn1cc(NC(=O)c2csc(-c3nncn3C(C)C)n2)cn1 +NC(=O)c1ccc(Oc2ccc(CNCCc3ccccc3)cc2)cc1 +CC(=O)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 +CSc1cccc(CN2CCCC(CO)(Cc3cccc(Cl)c3)C2)c1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(Cc4cccnc4)c4ccccc43)CC2)C(C)C)c1 +COc1ccc(C=CC(=O)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)cc1 +CCCCC#Cc1nc(NCc2cccc(Br)c2)c2ncn(C3OCC(O)C3O)c2n1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(c2cccc(CF)n2)CC1 +CC(Oc1c(N)ncc2c(-c3ccncc3)coc12)c1c(Cl)ccc(F)c1Cl +Cc1ccc2[nH]cc(-c3csc(NC(=N)NCc4ccccc4)n3)c2c1 +N#CCC1COc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc2N1CC(F)(F)F +Cc1nc(N)nc2c1cc(-c1cnn(C)c1)c(=O)n2C1CCC(O)CC1 +CCOn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccnc3)cc21 +COc1ccc(C(C(F)(F)F)C(F)(F)F)cc1CNC1CCCNC1c1ccccc1 +O=C(Nc1ccn(COP(=O)(O)O)c(=O)c1)c1cc(C(F)(F)F)ccc1Oc1ccc(F)cc1 +CCCC(NC(=O)N1CCc2cnc(NC(C)CO)nc2C1)c1ccc(OC)c(F)c1 +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1Cc2cccn3ncc(c23)C1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4cccc(Cl)c4)nc31)C(O)C2O +O=C(Nc1cccc(Cl)c1)Nc1nc2nn(CCc3c(Br)cc(Br)cc3Br)cc2c2nc(-c3ccco3)nn12 +O=S(=O)(Cc1ccc(Cl)cc1)NCCCCc1c[nH]cn1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccccc3)nn21 +Cc1nc2c(OCC3CCCCC3)cccn2c1C(=O)NC(C)(CO)c1cccc(C(=O)O)c1 +CC(C)C(C(=O)NS(=O)(=O)c1ccccc1)N1C(=O)C(=Cc2ccc(-c3ccccc3)cc2)SC1=S +CCN1CC(Cl)=C(c2cn(S(=O)(=O)c3ccc(OC)cc3)c3ccc(OC)cc23)C1 +CCCC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3cccnc3)c3ccccc23)CC1 +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(CCC(=O)O)C(=O)O +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(-c2cnco2)cc1 +Cc1ccc(C(=O)NC2C3CC4CC(C3)CC2C4)cc1S(=O)(=O)N1CCOCC1 +COc1ccc(C(C)C(F)(F)F)cc1CNC1CCCNC1c1ccccc1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(C3CC(F)(F)C3)n2)cc1OC(F)F +CCc1nc2c(C(=O)NC3CCCCC3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(C(=O)NCCCCO)c2)n1 +COC1(c2cc(Sc3ccc(C(C)=NO)cc3)cc(F)c2C)CCOCC1 +C=CC(=O)Nc1cccc(N2C(=O)N(Cc3ccccc3)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +CCNC(=O)C1OC(n2cnc3c(N)nc(N4CCN(c5ccc(OCCOC)cc5)CC4)nc32)C(O)C1O +Cc1ccc(-n2nc(C3CCN(CC4CC4)CC3)cc2NC(=O)c2cnn3cccnc23)nc1 +CC1=C(C(=O)N2CCCC2c2cc(C)on2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CN1CC2CC1CN2c1ccc(-c2ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn23)c(F)c1F +COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OC1COC2CCOC21 +Cc1ccc(-c2nnc(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)o2)cc1C +O=C(CC1COC1)NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1 +CCC(C)NS(=O)(=O)c1ccc(F)c(C(=O)NCc2ccc(F)c(F)c2)c1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(F)c(C)c3)nn21 +Cc1ccc(NC(=O)C2CCCCC2)cc1S(=O)(=O)N1CCOCC1 +CC(=O)c1cnc2cc(C)c(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1ccc(CN(C)C)cc1 +CCCNC(=O)c1nnsc1S(=O)(=O)c1ccc(Cl)cc1 +COc1cccc(Nc2cc(-c3cccc(-c4cccc(C(=O)NCCN(C)C)c4)c3)nc3c2C(=O)NCC3)c1 +Cc1nc(NC2CCCc3ccccc32)cc(-c2ccc(Cl)c(N)c2)n1 +S=c1[nH]c(=S)c2c3c(sc2[nH]1)CCCCC3 +C=CCN(CCN(Cc1cncn1C)c1ccc(C#N)cc1)S(=O)(=O)c1cn(C)cn1 +CC1CN(Cc2ccc(-c3ccccc3CN(C)C(=O)CS(=O)(=O)c3ccccc3)cc2)CC(C)N1 +CCCCCCCC(C)NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 +CCCCNc1nc(NCCCC)nc(NCc2ccc(S(N)(=O)=O)cc2)n1 +CC(=O)N1Cc2ccccc2CC1CN1CCC2(CCc3ccccc32)CC1 +Cn1c(Cc2nc(N3CCOCC3)cc(=O)[nH]2)nc2cc(F)ccc21 +Cc1ncc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1-c1ccnc(N2CCOCC2)c1 +FC1(F)CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)CC1 +O=C(c1ccon1)N1CCC(O)(c2ccccc2)C2CCCCC21 +O=C(Nc1ncnc2oc(-c3ccc(F)cc3)cc12)C1CCCC1 +CCN1C(=Cc2sc3ccc(OC)cc3[n+]2CC)C=Cc2cc(OC)ccc21 +O=C(NCCCNC(=O)c1ccc(O)c(O)c1)c1ccc(O)c(O)c1 +CCC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(n2c(O)nc3ccccc32)CC1 +CCCc1c(OCc2cccc(Oc3ncccc3-c3nn[nH]n3)c2)ccc(C(C)=O)c1O +CCCCN(CCN(C)CCc1ccc(O)c2[nH]c(=O)sc12)C(=O)CCOCCc1ccccc1 +C=C(C)c1ccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 +CCc1c(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(C)c3)no2)sc(C)c1CC(C)C +C=CC(OC)C(NC(C)=O)C1NC(C(=O)O)CC1C=CC +COc1ccc(CCn2c(=O)nc(NCCNC(=N)N)n(Cc3ccc(OC)cc3)c2=O)cc1 +N#CC1CSCN1C(=O)CN(N)C1CCN(CC(=O)Nc2ncccn2)CC1 +COC1CCC(Nc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1cccc(OCc2c(C#N)no[n+]2[O-])c1 +Cc1c(C(=O)NCCCN2CCN(c3cccc(Cl)c3)CC2)cc(-c2ccccc2)n1N1CCCCC1 +Cn1c(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)nnc1C1CCOCC1 +CC1OC(=O)C2CC3CCCCC3C(CCCN3CCOCC3)C12 +CC(C)Oc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)cc(OC(C)C)c1 +O=C1N(Cc2ccc3ccccc3c2)C(Cc2ccccc2)C(O)C(C(Br)Cc2ccccc2)N1Cc1ccc2ccccc2c1 +CCc1ncnc(NC(CC)c2ccc(Oc3ccc(F)cc3)cc2)c1Br +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3C4CCC(C4)C3N(Cc3ccco3)C1=O)N2 +COc1cccc(C=NNc2cc(C)nc(-c3ccccc3O)n2)c1O +N#Cc1ncc(F)c(N2CCC(S(=O)(=O)c3ccccc3C(F)(F)F)C2)n1 +NCc1cc(Cl)c(C(=O)Nc2ccnc(NC(=O)C3CC3)c2)c(Cl)c1 +CC(C)(C)COCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1 +COc1cccc(NC(=O)c2cc3c(s2)CCN(c2cccc(-c4nc5ccccc5n4C)c2)C3)c1 +CNC(=O)CNC(=O)C1CCCCN(C)C(=O)OCCCC(C(=O)NO)C(CC(C)C)C(=O)N1 +CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4ccc(F)cc4)ccc3Sc3ccc(N)cc3)ncnc2n1 +Cc1cc(N2C(=O)C3C4CCC(O4)C3C2=O)ccc1Cl +CC(Nc1cc(F)ccc1F)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +Cc1cnc(-c2c(-c3nc(C)n4ncnc(N5CCC5)c34)cnn2C)c(F)c1 +COc1ccc(-c2ocnc2C(=O)NCc2ccnc(C)c2)cc1Cl +CN(C1CCC(n2cc(C(N)=O)c(Nc3ccc(Cl)cc3)n2)C(C#N)C1)C(C)(C)C +CC(=O)Nc1cc2ncccc2cc1C=CC(=O)N1CCN(Cc2ccc(F)cc2)CC1C +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1ccccc1OC(F)(F)F +Cc1ccc(-c2cc(OCC(=O)O)ccc2Cl)c2c1CCN(C(=O)OCc1ccccc1)C2 +CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2ccc(C(C)C)cc2)CC1 +O=C1c2ccccc2CN1C1CCC(N2CCN(c3nsc4ccccc34)CC2)CC1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1C1CCOC1 +CCCCCCCCS(=O)(=O)Oc1ccc2c(C)c(C)c(=O)oc2c1 +O=C(NCC1(c2ccc(C(F)(F)F)nc2)CCC(F)(F)CC1)c1cccc(F)c1Cl +CCC(CSC(CCc1ccccc1-c1nn[nH]n1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O +c1cc(-c2n[nH]c3ccc(C4CC4)cc23)cc(N2CCOCC2)n1 +COc1cc(CN(CC(C)C)C2c3ccc(Cl)cc3CC2C(=O)O)ccc1OCCN1C(=O)CCC1=O +CCCN1CCC2(CC1)Oc1ccccc1C1CC(c3ccccc3Cl)=NN12 +N#Cc1nc(C(=O)NCC(=O)O)c(O)c2c1N(Cc1ccccc1)C(=O)CC2 +COc1ccc(-n2nc(C)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2F)cc1 +CC(=O)Nc1ccc2ccn(-c3cc(NCCCCO)n4ncc(C#N)c4n3)c2c1 +CCC1CCCC(C2(CC(=O)N3CCCCC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCCn1c(=O)c2nc(C=Cc3cccc(Cl)c3)[nH]c2n(CCC)c1=O +COC1CS(=O)(=O)c2cc(C(=O)N=C(N)N)c(C)cc21 +CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(C(=N)N)c2)nc(Oc2ccc(O)cc2C(=O)O)c1F +Cc1cc(Oc2nccc3[nH]ccc23)ccc1-c1cncc2nccn12 +CN1CC2(CNC(=O)c3c2[nH]c2c3CCc3cnc(-c4ccc(OCCN5CCOCC5)cc4)cc3-2)C1 +Cc1cc(C(N)=O)nn1-c1cccc(-c2ccccc2OCC(F)(F)F)c1 +CC1(C)Cc2cccc(N3CCN(CCc4ccc5c(c4)NC(=O)CO5)CC3)c2O1 +COC(=O)C1=C(CN2CCOCC2CCC(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Cl +COc1ccc2c(c1)c(C=C1C(=O)NN=C1c1cnns1)cn2C +N#Cc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1 +CCC1OCC(=O)C1NC(=O)C(CC1(C)CCCC1)NC(=O)c1ccc(NS(=O)(=O)c2nc(C)cs2)cc1 +CCc1ccc2c(c1)C1c3cc(O)c(O)cc3CCC1NC2 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(Br)cc1 +CC1(C(=O)OC2C[N+]3(CC=Cc4ccccc4)CCC2CC3)c2ccccc2-c2ccccc21 +Cc1cc(C)cc(-c2c(O)nc3cc(Cl)ccc3c2OCC2CCCNC2)c1 +Cc1cnc2nc1-c1ccnc(c1)OCCC=CCOCc1cc(ccc1OCCN1CCCC1)N2 +CC(=O)N1CCN(c2ccc(Nc3nccc(-c4sc(N)nc4C)n3)cc2)CC1 +CC1(N)CCC(Nc2c(C(N)=O)cnn3cc(-c4ccc(C(=O)NC5CC5)cc4)cc23)C1(C)C +Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3Cc3ccccc3)cc12 +CCCCC(C=NNC(=O)OC(C)C)NC(=O)OC(C)(C)C +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccc(-n4cccn4)cc3)o2)C(C)O)c(C)c1Cl +Cc1ccc(-c2c(O)nc3cc(Cl)cc(Cl)c3c2O)cc1 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+CC(Oc1cc(-n2cnc3ccc(OCC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F +Nc1ncc(-c2ccncc2)nc1C(=O)Nc1ccccc1 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2cccc(C(F)(F)F)c2)c1)C(F)(F)F +Cc1c(OCCCCOc2cccc(F)c2F)ccc(C(=O)CC(C)C)c1O +COCCCn1c(CN2C(=O)C(=NOCCCN3CCCCC3)c3ccccc32)nc2ccccc21 +COc1ccccc1-c1ccc(CC(NC(=O)C2CCCN2)C(=O)O)cc1 +CC(NS(=O)(=O)c1cccs1)C(=O)NC1=NN=C(c2ccc(Cl)cc2)CS1 +Cc1cc2c(cc1C)C(=O)CC1(CCN(C(=O)c3cccc4cn[nH]c34)CC1)O2 +O=C(Nc1cccc(Cl)c1)c1cccnc1SCc1ccncc1 +CCc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)O)n2Cc1cc([N+](=O)[O-])ccc1F +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(OC)cc3OC)ncc2Br)c1 +COc1ccc(Nc2ncc(F)c(Nc3ccc(OC)cc3)n2)cc1 +CC(=O)OC1CC2CC3(CCC2(C)C2CCC4(C)C(C(C)CCC(=O)O)CCC4C12)OOC1(CCCCC1C)OO3 +CCCCOc1cc(N(CC)c2ccc(C(=O)O)cn2)ccc1C(C)C +O=C(O)CC1c2ccccc2C(=O)N(CC(=O)NCCCCNc2nc3ccccc3[nH]2)c2ccccc21 +CCOCC(=O)NC(C)C(=O)N1CCN(CCCOc2ccc(-c3noc(-c4ccccc4)n3)c(F)c2)CC1 +O=C(O)CCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21 +CC(C)Oc1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(Cl)c2F)C1 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+C=CC(=O)Nc1cc(Nc2nccc(-c3cn4c5c(cccc35)CCC4)n2)c(OC)cc1N1CCC(CN(C)C)C1 +COCC(C)Oc1cc(C#Cc2cccc(N(C)C)c2)cc(C(=O)Nc2ccn(C)n2)c1 +Cc1ncc([N+](=O)[O-])n1CCOC(c1ccccc1)c1ccccc1[N+](=O)[O-] +CCC(Nc1ncnc2[nH]cnc12)c1cc2ccccc2c(=O)n1-c1ccccc1 +Cc1cc(OCCC(C)O)cc(C)c1-c1ccc(F)c(COc2cc3c(cn2)C2C(C3)C2C(=O)O)c1 +Cc1cc(NCC(N)c2ccccc2F)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +COc1cc(C=C2CCCN3CCC(c4ccc(F)cc4)ON=C23)ccc1-n1cnc(C)c1 +CC(NC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OCc1cc2ccccc2o1)c1ccccc1 +C=C(C)CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1 +CCCC1(N2CCN(c3cc4c(cn3)C(=O)c3c([nH]c5cc(C(N)=O)ccc35)C4(C)C)CC2)CCC1 +O=C(Nc1ccn(Cc2c(F)c(F)cc(F)c2F)n1)c1ccc(COc2ccccc2Cl)cc1 +Cc1ccccc1S(=O)(=O)c1ccc(C(C)(O)C(F)(F)F)cc1 +CCc1ncnc(N2CCN(Cc3nc(C)c(C)o3)CC2)c1C#Cc1ccc(N)nc1 +O=C(O)c1csc(-n2nc(-c3ccccc3)c(F)c2-c2ccccc2)n1 +O=C(OCN1C(=O)C2=C(CCCC2)S1(=O)=O)c1c(Cl)cccc1Cl +O=C1c2ccccc2NC(c2ccccc2F)N1CCCCCN1C(=O)c2ccccc2NC1c1ccccc1F +CCOC(=O)C1=C(c2ccccc2)OC(=C(C#N)C(F)(F)F)S1 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cnc(-c5cccnc5)s4)c3)cc2C1 +Clc1c[nH]c2ncc(-c3cncc(N4CCOCC4)n3)cc12 +CCNc1nc(Nc2cn(S(=O)(=O)CCOC)nc2C)ncc1C(F)(F)F +COc1cc(C)c2nc3[nH]nc(C)c3c(C(O)c3ncco3)c2c1 +O=c1[nH]c2c(O)ccc(C(O)CNCCCOCCOCCc3ccccc3)c2s1 +CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cccc(C)c2)n2nccc2N1 +COc1nc(-c2ccc(-c3ccccc3S(=O)(=O)NC(C)(C)C)cc2F)cnc1N +CCC(C(=O)NC(CC(=O)O)C(=O)CCCc1ccccc1)n1cc(C(C)(C)C)nc(Nc2nnn[nH]2)c1=O +Cc1cc(C)n(-c2cc(-n3[nH]cc(-c4cccnc4)c3=O)ncn2)n1 +CC(C(=O)N1CCc2c(F)cccc21)c1nc(N2CCOCC2)c(F)c(=O)n1C +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)Nc5cccc(OC(F)(F)F)c5)cn4c3)cc2)CC1 +O=C(O)CCCCCCCCC=C(c1ccccc1)c1cccnc1 +CC(O)(COc1ccc2[nH]ccc2c1)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCC4(C)CCCO4)ncc23)ccn1 +CN1CCN(Cc2ccc(Nc3ncc4cc(-c5c(Cl)cccc5Cl)c(=O)n(C)c4n3)cc2)CC1 +NC(=O)c1ccc(-c2cc3cc(O)ccc3o2)c(F)n1 +CNC(=O)c1cc2cc(C(=O)N3CCC4(CC3)CC(=O)c3c(OC)cccc3O4)ccc2[nH]1 +Cc1ccc(-n2c(C)nnc2SCC(=O)Nc2ccc(C(C)C)cc2Br)cc1 +CC1CCCC(=O)C(C)CCC=Cc2cc(O)cc(O)c2C(=O)O1 +CNC(=O)C1CCC(NC(=O)c2cnc(-n3ncc4cc(Cl)cnc43)cc2NC(C)C)CC1 +CN(Cc1ccc(CC(=O)O)cc1)c1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1 +CCCCCCCCCOC(=O)C1=C(c2ccccc2)CCN(CC)C1 +CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4ccncc4C3=O)CC2)CC1 +Cc1cc(Cl)ccc1-c1ccc2[nH]c3c(c(=O)c2c1)CSCC3 +NC(=O)c1ccc(-c2cc(C(F)(F)F)nc3c(-c4cnc5ccccc5c4)cccc23)cc1N +CCc1cc2cc(NS(=O)(=O)c3ccc(C#N)cc3)ccc2n(C)c1=O +CCCCCc1cc(O)cc(OCCCCCCCC(=O)NC2CC2)c1 +CC(=O)N1CCc2c(nc(C)n2C2CC3CCC(C2)N3CCCN(C(=O)Nc2ccc(C)cc2)c2ccc(F)cc2)C1 +COc1ncc(F)cc1C1CCCN1c1ccn2ncc(C(=O)N3CC(C)(O)C3)c2n1 +COc1ccc(CNC(=O)c2ccccc2Sc2ccc3c(C=Cc4ccccn4)n[nH]c3c2)cc1 +O=C(CCC(=O)n1sc2ccccc2c1=O)c1cccs1 +CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(-c4ccc5nc(C)oc5c4)c[nH]c3n2)c(OC)c1 +CC(C)c1ccc(COc2ccc(N(CCN)C(=O)c3ccc(Cl)cc3Cl)cc2)cc1 +N#Cc1ccc(CC(=O)NC2COc3ncccc32)c(Cl)c1 +Clc1cc(Nc2ncnc3ccc(-c4cccc(N5CCOCC5)c4)cc23)ccc1OCc1ccccc1 +COc1ccc(Oc2c(Cl)cnn(Cc3ccccc3C(C)C)c2=O)cc1 +CCOc1ccc(C=C(C#N)c2nc3ccccc3[nH]2)cc1OC +CCCCC(Sc1ccc(OCCCOc2cccc(C(F)(F)F)c2)cc1)C(=O)O +CCCCCCCCC(=O)N1CCN(C(CC)c2nc3ccccc3c(=O)n2C)CC1 +O=C(O)C(O)(Cc1cnc2ccccn12)P(=O)(O)O +CC(C)(C)NC(=O)N1CCn2c(c(C(N)=O)c(-c3cccc(C(F)(F)F)c3)c2C2CC2)C1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(F)c(Cl)c4)nc23)N1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +CCc1cc(=O)oc2nc(OCC3CC3)[nH]c(=O)c12 +Cn1c(=O)[nH]c2nccc(Oc3ccc(NC(=O)Nc4cc(C5CC5)nn4-c4ccccc4)cc3)c21 +CCOc1ccccc1N(C(=O)CC)C1CCN(CCc2ccccc2)CC1 +CC(C)N1CCC(Oc2ccc(-c3ccc(=O)[nH]n3)cn2)CC1 +O=c1oc2cc(OCC(O)CN3CCN(Cc4ccc(Cl)cc4)CC3)ccc2c(O)c1[N+](=O)[O-] +O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1cc(N2CCOCC2)ccc1C(F)(F)F +O=[N+]([O-])c1ccc2c(c1)C(c1ccccc1Cl)=Nc1c(n[nH]c1-c1ccncc1)N2 +N#CC1CCCCC1n1cc(C(N)=O)c(Nc2ccnnc2)n1 +CN(C)CC1CCN(c2ccc(Cl)cc2NC(=O)c2cnn3cc(O)cnc23)CC1 +Nc1nc(CNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)cs1 +O=C(c1ccc([N+](=O)[O-])cc1)N1c2ccccc2Sc2ccccc21 +CC1CCC2C(C)C(Oc3ccc(F)cc3)OC3OC4(C)CCC1C32OO4 +CCc1c(C)nc(O)c([N+](=O)[O-])c1Oc1cc(C)cc(C)c1 +CC(NC(=O)Nc1cc2[nH]nc(C(=O)NCc3cccnn3)c2cn1)c1ccccc1 +O=C(C=Cc1cccc(Cl)c1)NCCCCCN1CCC(c2c[nH]c3ccccc23)CC1 +CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(CNC(=O)CCc3ccc(N=[N+]=[N-])c(I)c3)ccc21 +Cc1ccc2oc(=O)c(C=Nc3ccc(S(=O)(=O)Nc4cc(C)on4)cc3)c(Cl)c2c1 +O=C(O)CCc1ccc(COc2ccccc2)cc1C(=O)NCc1ccccc1 +COc1cc(Nc2nc(NCCCNc3ccnc4cc(Cl)ccc34)nc(N3CCOCC3)n2)cc(OC)c1 +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C2CCCC2)co1 +O=C(NC1CC2CCC(C1)N2CC1CCCO1)c1cccc2ccccc12 +CCC(=O)N1C(C(=O)O)Cc2c([nH]c3ccccc23)C1c1cccc(O)c1 +CC(C)Oc1sc(-c2cc[nH]n2)c2c1C(=O)CC(C)(C)C2 +Oc1cc(C=CF)c2oc(-c3ccc(O)c(F)c3)nc2c1 +COc1ccccc1N1CCN(CC(=O)Nc2cccc(C)c2)CC1 +NCc1ccc2c(c1)CN(C(=O)Nc1ccc(NC(=O)CC3CCCC3)cc1)C2 +CON(C)CC(NC(=O)C(CC(=O)N1CCOCC1)Cc1ccccc1)C(=O)NC(CC1CCCCC1)C(O)C(O)CC(C)C +NC(CC(c1ccccc1)c1ccccc1)(C(=O)O)C1CC1C(=O)O +CCCCC12CC1(C(=O)Nc1cccc(C#N)c1)C(=O)Nc1ccc(Cl)cc12 +O=C1OC(c2ccccc2Cl)CN1c1ccc2c(c1)CCNC2 +CCc1cccc(CC)c1NC(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC(C)C)cc1 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+CC(C)(N)C(=O)NC(CCc1ccccc1)C(=O)N1CCC2(CC1)CSc1ccccc12 +COc1ccc(C=CC(=O)Nc2cc(-c3c(-c4ccc(F)cc4)nc(SC)n3C)ccn2)cc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCc3ccncc3)c2)[nH]1 +O=C(Nc1nnc(C2=COCCO2)o1)c1ccc(Br)cc1 +CC(C)(C)C1COC2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N21 +CC(C)CC(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)c1cccnn1 +Clc1ccc(-c2csc(NN=C3CCCCCC3)n2)c(Cl)c1 +O=C(O)CC(NC(=O)Cn1c(Cc2ccccc2)ccc(NC(=O)c2cccc3ccccc23)c1=O)C(=O)COc1ccccc1 +Cc1[nH]c2ccc(OC(F)(F)F)cc2c1Cc1cccc(OC(C)C(=O)O)c1 +O=C1c2ccccc2C(O)(c2ccc3[nH]c(Nc4ncc(Cl)cn4)nc3c2)N1c1cccc(Cl)c1F +O=S(=O)(Nc1ccc(Oc2cncc(Cl)c2)c(Cl)c1)c1ccc(Cl)cc1Cl +CC(C)(C)c1ccc(CCN2CCc3cc(S(=O)(=O)Nc4ccc(OCCOCC5CCCO5)cc4F)ccc3C2)cc1 +CC(C)C(CC(=O)OCC1(CO)CC(=Cc2ccc(O)cc2)C(=O)O1)C(C)C +O=C(NC(CCc1ccccc1)CNc1ccc(OC(F)(F)F)cc1)OC(CC1CCCCC1)C(=O)N1CCOCC1 +CC(C)(C)CC(=O)N1CCCC1C(=O)NCc1ccc(C(=N)N)cc1 +CCn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(C)c4)cc2)CC3)cn1 +NNC(=O)c1[nH]c2ccc(Cl)cc2c1Sc1ccccc1 +CN(C)C1CCN(c2ccc(NC(=O)c3ccc(-c4cccs4)cc3)cc2)C1 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+O=C(NC1CCCc2c1[nH]c1ccc(Cl)cc21)c1ccccc1 +CC(C)(C)NCC(O)COc1cccc2c1NC(=O)CC2 +Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc([N+](=O)[O-])cc1 +COC(=O)C1=C(CN2CC(C)(C)CC2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Cl +CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)c2ccccc21 +CCCCNc1cc(NC(C)C(Cc2ccc(Cl)cc2)c2cccc(Br)c2)nc(SC)n1 +Cc1cc(C)n2nc(-c3ccc(CCCF)cc3)c(CC(=O)N(C)Cc3ccccc3)c2n1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1c(-c2ccc(Br)cc2)noc1C +Cc1cc(F)ccc1OC1CCN(CC2CCN(C(Cc3ccc(F)cc3)C(=O)O)CC2)CC1 +O=CN1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1N1CCOCC1 +Nc1nc(N)c2ncn(C3SC(CO)C(O)C3O)c2n1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cc2ccccc2n1CCCCO +Cc1cccc(C)c1Nc1ccc2c(c1)CN(CCCCCCC(=O)NO)C2=O +CC1CCC2C(Cc3cccc(F)c3)C(=O)OC3OC4(C)CCC1C32OO4 +CCNC(=O)N1CCC(NCc2cc(OC(F)(F)F)ccc2OC)C(c2ccccc2)C1 +O=c1c2cc(C#CCc3ccccc3)ccc2ncn1Cc1ccc(F)cc1 +CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2ncncc2O)cc1 +CC(C)(C)OC(=O)NCCNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +O=C(C(O)c1ccccc1)N1CCC(Nc2ccc3[nH]ncc3c2)CC1 +CCCc1nc(C(=O)NCC(O)CN2CCN(c3cccc(C)c3C)CC2)cn1-c1ccccc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(=O)COc3cccc(Cl)c3Cl)c2)[nH]1 +CCOc1cc(-c2cc(C3CCN(C4COC4)CC3)n(C(C)C)n2)cnc1N +Cn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(Cl)cc2)CC3)cn1 +O=C1CC(CN2CCC(Oc3ccccc3)CC2)CCc2ccccc21 +O=C(CN1CCOCC1)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +COc1cccc(CNC(=O)CCC2CCCN(Cc3cc4ccccc4o3)C2)c1 +CC1(N2Cc3c[nH]nc3C2)COC(c2cc(F)ccc2F)C(N)C1 +Cc1nc2ccccc2n1Cc1ccc(CNC(=O)C(O)C(O)C(=O)N2CCCC2c2csc(N)n2)s1 +O=C(C=Cc1ccc(C(F)(F)F)cc1)Nc1ccc(F)cc1 +CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CC(=O)O)c4c3)cc12 +O=C1C=CC(=O)c2c1ccc1c2c(=O)[nH]c2ccc(Cl)cc21 +COc1cc(C)c(C(=O)N2CC3CN(CCC(NC(=O)C4CCCC4)c4ccccc4)CC3C2)c(C)c1 +Cc1cc(SC2=C(O)OC(C)(CCc3ccc(O)cc3)CC2=O)c(C(C)(C)C)cc1NS(C)(=O)=O +CC12CCC3c4ccc(C(=O)NCC(=O)O)cc4CCC3C1CC=C2c1cncc(F)c1 +O=c1ccc(-c2cc(F)cc(F)c2)nn1CC1CN(c2ncc(-c3cnn(C4CCNCC4)c3)cn2)CCO1 +O=C(O)c1cc2ccc(Cl)cc2n1Cc1ccc(Cl)c(Cl)c1 +CC(C)n1cnc2c(NCc3ccc(-n4cccc4)cc3)nc(NC3CCC(N)CC3)nc21 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+Nc1nc(Cl)nc2c1ncn2C1OC(COC2CC2)C(O)C1O +CCCc1c(OCCCCOc2cccc3c2ccn3CC(=O)O)ccc2c(C(F)(F)F)noc12 +C=CC(=O)Nc1cc(OCCOC)ccc1Nc1cc(N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)ncn1 +Cc1ncnc(N2CCN(C(=O)C3CCC3)CC2)c1C#Cc1ccc(N)nc1 +O=c1cc(N2CC3CC2CO3)nc2n1CCC(C(F)(F)F)N2CCC1CCOCC1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCCc1nc(C)c(CCc2ccccc2)[nH]c1=O +CC(C)(C)c1ccc(-c2cc(Nc3ccc4c(c3)OCCO4)cnn2)cc1 +COc1cc(CN(CC2CCCC2)C(CC(=O)O)c2ccc(C(F)(F)F)cc2)ccc1OCCN1C(=O)CCC1=O +COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COC1=C(Cc3ccccc3)C(=O)OC1)C2=O +O=C(c1ccc(Cl)cc1)N1CCN(C(=O)N2CCOCC2)CC1 +CCN(CC)Cc1ccc(NC(=O)c2ccccc2)c(C(=O)C(=O)N(CC)CC)c1 +CN(C)C(=O)N1CCN(C(=O)C(Cc2cccc(C(=N)N)c2)NS(=O)(=O)c2ccc3ccccc3c2)CC1 +CSc1cc2c(cc1OS(N)(=O)=O)CCC1C2CCC2(C)CCCC12 +CS(=O)(=O)NC(=O)c1cc(Cl)c(-n2nc(Cl)c3cc(-c4cc(F)c(F)c(F)c4)ccc32)cc1F +N#Cc1cc2c(cc1F)nc(-c1cncc(F)c1)n2C1CC1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NS(=O)(=O)CCC(=O)O)no2)cc1C#N +Cc1cccc(CNC(COCc2ccccc2)C(=O)N2CCC3(CC2)CN(S(C)(=O)=O)c2ccccc23)c1 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+CC1CCc2cc(-c3ncccc3CO)ccc2N1C(=O)c1ccc(O)cc1O +COc1cc(OC)cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncc(F)cn5)ccc43)cc2F)c1 +CC(NC(=O)c1cccc2c1N(Cc1cccc(C#N)c1)CC2)c1ccc(C(=O)O)cc1 +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(N(C)C(=S)Nc4ccc(Cl)cc4)cc3)CC21C +c1ccc2c(c1)c1c(n2Cc2ccc(Cn3c4c(c5ccccc53)CCC4)cc2)CCC1 +CC1=C(c2ncnn2C2CCCC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CCOC(=O)CN1N=C(c2ccc(OC)c(OC)c2)C2CCCCC2C1=O +Cn1c(=O)c2nc(-c3ccc(-c4ccccc4)cc3)[nH]c2n(C)c1=O +COc1nc(C2CC2)c(C(=O)NC2C3CC4CC2CC(O)(C4)C3)s1 +COc1ccc(C2=NCCN2)cc1-n1cc(-c2ccc(C3=NCCN3)cc2)nn1 +CCN1C(=O)C2Cc3c([nH]c4ccccc34)C(c3ccc(Cl)c(Cl)c3)N2C1=O +CCCC(CCC)Oc1c(Br)cc(-c2ccccc2-c2nnn[nH]2)cc1NC(=O)Nc1ccccc1F +Brc1cnc(NCCc2cccs2)nc1Nc1cc(C2CC2)n[nH]1 +O=C(Nc1ccccc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +Cn1nccc1-c1cccc(CC(NC(=O)c2ccccc2)C(=O)NCC#N)c1 +CCCN(CCC)C(=O)Cc1c(-c2ccccc2)nc2ccc(C)cn12 +CCNC(=O)C1CCN(c2cccc3c2C(=O)N(C2CCCCCCC2)C3=O)CC1 +Cc1cc(NC(=O)Nc2ccc(F)cc2F)c2ccccc2n1 +COc1ccc2c(c1)C(=Cc1cc3c([nH]1)CCN(C(=O)CCN)C3)C(=O)N2 +O=C(NC(c1ccc(O)cc1)P(=O)(Oc1ccccc1)Oc1ccccc1)OCc1ccccc1 +Cc1ccccc1-c1cc(C(OCc2ccc(Br)cc2)c2cncn2C)ccc1C#N +CC(=O)NC1CCCc2c(-c3ccc(C(F)(F)F)c(F)c3)cncc21 +Cc1cccc2c(C3OCC(O)C(O)C3O)cn(Cc3ccc(C4CC4)cc3)c12 +CC1CCC(C(C)C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)C2Cc3c(cnn3-c3ccccc3)CC12 +CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 +COc1cc(OCCN2CCCC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1cccc(C)c1Cl)CC2 +CC(C)C(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)CCc2ccc(Cl)cc2Cl)CC1 +CCOC(Cc1ccc(OCC=Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1)C(=O)O +Clc1ccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)cc1 +COc1cc(C)cc(-c2c(-c3cc(NCCCCO)nc(-c4cccnc4)n3)cnn2C)c1 +Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccccc5)cc4)csc23)cn1 +c1cc(OCC2CNCCO2)c2nc(-c3nnc4ccccn34)ccc2c1 +CCCOc1ccc(-c2nc(COc3ccc(OCC(=O)O)c(C)c3)sc2-c2ccc(OC(F)(F)F)cc2)cc1 +CON(Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F)C(=O)C(C)C +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1cccc(F)c1)CC2 +CN(C)c1nc2c(c(Nc3ccc([N+](=O)[O-])cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +COc1cc(-c2cc(NC(=O)Nc3ccc(OCCN4CCCC4)cc3)cc(OC)c2OC)ccc1C(C)=NO +COc1ccc(N(C)c2nc(C)nc3ccccc23)cc1OCCCCC(=O)NO +COc1ccc(OC(CCN2CCN(c3ccccc3OC)CC2)c2ccccc2)cc1 +CC(=O)SCCC(CCCCC(=O)N(C)CCOc1ccc(CC2SC(=O)NC2=O)cc1)SC(C)=O +COc1cc2c(c(C)c1O)C=CC1C(C)(C(=O)O)CCCC21C +NC(=O)C1CC(F)(F)CN1C(=O)c1ccc(C2(O)CCC2)c(OCC2CC2)n1 +Fc1ccc(CCN2CCN(c3[nH]cnc4c5c(Cl)cccc5nc3-4)CC2)cc1F +COC(=O)N1CCC2(CC1)CC(O)(C#Cc1cccc(C)c1)CO2 +CC(C)(O)CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1CC1CCCO1 +Ic1ccc(Oc2cncc3sc(-c4nn[nH]n4)cc23)cc1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2ccc(Cl)c(F)c2)c2cc[nH]c2c1=O +Nc1noc2cccc(C(=O)Nc3cccc(CNC(=O)Nc4cccc(F)c4)c3)c12 +CN(C)C(=O)c1ccc(-c2nnn3c2CN(C(=O)CC(N)Cc2cc(F)c(F)cc2F)CC3)cc1 +CCCCCOc1ccc(C(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +O=C(O)C(Cc1ccc(O)cc1)=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 +Cc1c(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)ncn1CCN1CCOCC1 +Cc1c(C(=O)NC(=O)OCC(C)(C)C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1nc(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)c(C)c2ccccc12 +O=C(Cc1ccc(OCCC2CC2C2CCN(c3ncc(Cl)cn3)CC2)cc1F)N1CCCCC1 +NC(Cn1ccc(=O)n(Cc2ccsc2C(=O)O)c1=O)C(=O)O +CC(=O)Nc1cc(CCOc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1 +O=C(NCC1CCOC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=C(O)c1ccc(C(=O)C(=Cc2ccc(F)c([N+](=O)[O-])c2)SCc2ccc(C(F)(F)F)cc2)cc1 +O=C1CCNc2cc[n+](c3ccccc23)CCCCC[n+]2ccc(c3ccccc32)NCC1 +Cc1c(=O)n(Cc2ccccc2)c(=O)n2cc(C(=O)N3CCC(Oc4ccccc4F)CC3)sc12 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1c[nH]c2ccccc12)OCc1ccccc1 +O=C(CC(S)C(F)(F)F)NC(Cc1c[nH]c2ccccc12)C(=O)O +Clc1ccc(-c2ccc(C3=NOC(c4ccncc4)N3c3ccc(C4CCNCC4)cc3)o2)cc1 +CCOCCn1c(COc2ccc(C=CC(=O)c3cc(-c4nn[nH]n4)ccc3O)cc2)nc2ccccc21 +CC1(C)c2cc(OCCNS(N)(=O)=O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)c1cccc([N+](=O)[O-])c1)CC2 +O=C(NC1(C(=O)NC(CCCN2CCN(CC3CCOCC3)CC2)Cc2ccccc2)CCCC1)c1cc2cc(Cl)ccc2o1 +Cc1ccc2c(c1)C(=O)N(C)c1cnc(Nc3cccc(S(=O)(=O)N4CCC(O)CC4)c3)nc1N2C 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+O=C(c1cc(Cl)ccc1-n1nccn1)N1CCOCC1Cc1cc(-c2ncon2)ccc1F +O=C(Nc1ccccc1)Nc1ccc(C#Cc2ccc3nccn3n2)cc1 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1Nc1ccc(OCCN3CCOCC3)cc1CC2 +Cn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(C)c1=O +Cc1ccc2nc(N(C)C)nc(NCc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)c2c1 +CCC(C)(O)C(=O)OC1C(=O)OC2CC3C(C)=CC(=O)C(O)C3(C)C3C4(O)OCC23C1C(C)C4O +CN(CCCNCc1ccc2c(c1)OCCO2)c1nc(-n2ccnc2)ns1 +CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5ncccn5)COC4)ccc3C)c(F)c12 +CC(c1ccccc1)N1CCCC1C(=O)Nc1ccc(C=Cc2ccc(NC(=O)C3CCCN3C(C)c3ccccc3)cc2)cc1 +CCCCc1nc2cccnc2n1CCCCCOC(O)=C1C(C(C)C)=NC(C)=C(C(=O)Nc2cccnc2)C1c1ccccc1Cl +COc1cc(F)ccc1-c1nc(Nc2cc(CS(C)(=N)=O)cc(C(F)(F)F)c2)ncc1F +O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +Cc1ccc2[nH]nc(NC3CCN(Cc4ccc5c(c4)OCO5)CC3)c2c1 +C=C1C(=O)C23C(OC(=O)C=Cc4ccccc4OC)C1CCC2C12C=CCC(C)(C)C1C(O)C3(O)OC2 +CCN(CCOC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +COc1ccc(C2CCN(CC3CCN(C(=O)C=Cc4ccc(Cl)c(Cl)c4)CC3)CC2)cc1 +CCCn1c(=O)c2nc(C3CCCC(NC(C)=O)C3)[nH]c2n(CCC)c1=O +CCN(CC)CC(O)COc1ccccc1C(=O)CCc1ccccc1 +Cc1ccc(N2CCc3ncnc(NCc4ccc(C)c(F)c4)c3C2)c(C#N)c1 +CCC1C2Cc3ccc(O)cc3C1(CC)CCN2Cc1ccoc1 +CN1CCN(CC(=O)NCCNc2ccnc3cc(Cl)ccc23)CC1 +CC=Cc1cccc2c(=O)oc3c(C)c(O)ccc3c12 +CS(=O)(=O)c1ccc(-c2[nH]c(SC#N)cc2-c2ccc(F)cc2)cc1 +O=C1c2ccccc2C(=Cc2ccc([N+](=O)[O-])cc2)c2sccc21 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3C(=O)N3CCOCC3)cc2)cs1 +COc1ccc2c(c1)C(=O)C(=Cc1cc(Br)c(O)c(OC)c1)C2=O +CCc1cnn2c(NCc3cccnc3)cc(-c3ccccc3)nc12 +CCOc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 +CSc1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 +O=C(Nc1ccc2c(c1)C=Nc1c(Cl)ncnc1O2)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cc1ccc(N=Cc2nc(-c3ccc(C(F)(F)F)c(F)c3)oc2O)c(C(=O)O)c1 +CN1C(=O)CCc2c(NC(=O)NC3CCC(c4ccccc4F)C3)cccc21 +COCCN1CCN(c2ccc3ncnc(Sc4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4C)c3n2)CC1 +CCc1cnc(C)nc1-c1ccc(N(Cc2ccsc2)C(=O)c2ccc(O)cc2O)cc1 +CCn1cc(Br)c2cnc(NC(=O)c3ccc(C(C)(C)O)cc3)cc21 +COc1ccc(S(C)(=O)=O)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 +Nc1nccc(Oc2ccc(-n3cc(C(=O)NCc4ccc(F)cc4)ccc3=O)cc2F)c1C#CCO +O=C(CCc1ccc(Nc2nccc(Nc3cc(C4CC4)n[nH]3)n2)cc1)NCCN1CCCCC1 +O=C(Nc1cc(OC(F)(F)F)cc(-c2cccnc2)c1)N1CCc2ccc(Cl)cc21 +O=C(Cc1ccccc1)Nc1ccc2c(c1)C=CS(=O)(=O)O2 +COC(=O)CCC(=O)NC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5 +CCCn1cc(-c2ccccc2)nc1SCc1cn2c(C)cc(C)nc2n1 +O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CCN(Cc2ccccc2-c2ccc3ccccc3c2)C1 +Cc1cc(-c2cn(CCN3CCCC3)c(C3CCN(c4ncnc(N)c4OC(C)C)CC3)n2)ccc1F +COc1ccc(-n2c(C)nc(C(=O)NCC(O)CN3CCN(c4cccc(Cl)c4C)CC3)c2C)cc1 +Cc1nc2c([N+](=O)[O-])c(Cl)c(Cl)cc2n1Cc1ccc(C#N)cc1 +CNC(=O)C(NC(=O)C(CC(C)C)C(NCCCSC)C(=O)NO)C(C)(C)C +CCOC(=O)C1=C(CC)NC2=C(C(=O)CC(C)(C)C2)C1c1ccc(Cl)cc1Cl +CC(C)=CC(=O)Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1ccccc1Cl +Cc1nc(-c2ccc(CNC(=O)NC(CC(C)C)C(=O)N(C)N(C)C#N)cc2)no1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ncc(-c2cccc(C(F)(F)F)c2)cn1 +CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1C(C)C +O=C(Nc1cccc2c1OC(C(=O)O)CN2)c1ccc(OCCCCc2ccccc2)cc1 +Cc1ccc(N2OC3C(=O)N(c4ccc(C(=O)O)cc4)C(=O)C3C2c2ccccc2O)cc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1cc(-c2ccc(Cl)c(Cl)c2)no1 +COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OCCCCCC(=O)NO +COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(NS(=O)(=O)c2ccccc2)cc1 +CC(O)C(CCc1cccc(Cl)c1Cl)n1cnc(C(N)=O)c1 +O=C(O)c1cccc(NC(=O)c2nc(C3CCCCC3)[nH]c2COC23CC4CC(CC(C4)C2)C3)c1 +CCCn1cnc2c(N3CCOCC3)cc(-c3ccc(NC(=O)NCC)cc3)nc21 +Cc1c[nH]c2ncnc(N3CCC(CCN(C)C)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12 +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2nc3ccccc3s2)CC1 +NS(=O)(=O)c1ccc(Sc2c(F)c(F)cc(F)c2F)c(C(=O)NCCc2ccccn2)c1 +CCN(CC)Cc1ccc(-c2ccc(CN(CC)CC)cc2)cc1 +CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1C +CN1CC=C(c2cc(C(F)(F)F)ccc2N2CCOc3cc(S(=O)(=O)Nc4ccncn4)ccc32)CC1 +COc1cc2c(c(OC)c1OC)-c1c(cc3c(c1OC)OCO3)CC(C)C(C)(O)C2OC(=O)c1ccccc1 +Cc1ccc(C(=O)N(CCCN)C(c2oc3cc(Cl)ccc3c(=O)c2Cc2ccccc2)C(C)C)cc1 +Cc1ccncc1CCCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCC(=O)O +CC1(C)CC(=O)C(C(C2=C(O)CC(C)(C)CC2=O)c2ccccc2)=C(O)C1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1ccccc1Cl +CCc1ncnc(N2CCN(C(=O)NC)CC2)c1C#Cc1ccc(N)nc1 +CCCCCCCCCCCC[n+]1ccc(C(=O)NCCCCCCNC(=O)c2cc[n+](CCCCCCCCCCCC)cc2)cc1 +CC(NC(=O)OCc1ccccc1)C(=O)NC(CCc1ccccc1)CNc1ccc(N2CCCCC2)cc1 +COc1ccc(S(=O)(=O)N2CCOC23CCN(C(=O)Nc2ccccc2)CC3F)cc1OC +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(Oc2cc(Cl)ccc2Cl)C1 +CC(C)CCc1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 +CCCCSCC(=O)N1N=C(c2cc3ccccc3oc2=O)CC1c1ccc(C(F)(F)F)cc1 +Cc1ccc(CN2CCCC(N3CCC(c4ccc(O)cc4)CC3)C2=O)cc1 +O=C(O)CC1Sc2ccccc2N(Cc2nc3c(F)c(F)cc(F)c3s2)C1=O +Clc1ccccc1-c1cc(NCOc2cccnc2)n2ncc(Br)c2n1 +O=S1(=O)Nc2c(cc(Cl)c3cccnc23)-c2ccccc21 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(NCc3ccccc3)cc(-c3ccccc3)n2)CC1 +COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CN(C)CCO1 +O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc(COc2ccc(C(F)(F)F)cc2)cc1 +N=C(N)NCCCC(NC(=O)C1CCC2CN(S(=O)(=O)Cc3ccccc3)CC(=O)N21)C(=O)c1nccs1 +CCN(CC)c1nc(C)nc2c1ncn2-c1ccc(C(C)C)cc1Br +CN(CCO)c1cc(Sc2nc3ccccc3s2)c2nonc2c1[N+](=O)[O-] +CC1CCCN1C1CCN(c2ccc(N3CCC4(CCNCC4)C3=O)c(C(F)(F)F)c2)CC1 +COc1cc(-c2cc3ncccc3c(OCC3CNC(=O)C3)n2)cc(OC)c1OC1CCOCC1 +O=C(NC1CC(=O)N(c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)C1=O)OCc1ccccc1 +COc1cc2c(cc1OC)C(CC(c1ccccc1)c1ccccc1)N(C(=O)C1CCCCC1)CC2 +CCC1(N2CCC(n3c(=O)c(C(=O)O)nc4ccccc43)CC2)CCCCCCC1 +Cn1c(C#N)ccc1-c1cc(F)c2c(c1)C(C)(C)C(=O)N2CCc1ccccc1 +COc1cc(CNC(=O)C=C(C)C=CC=C(C)C=CC2=C(C)CCCC2(C)C)ccc1O +CC(C)(C)CCN1CCN(CC2CCC(c3ccc(Cl)cc3Cl)N(c3ccc(Cl)cc3)C2)CC1 +Cc1ccc(OCC(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)c(C)c1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc[nH]c1=O +O=[N+]([O-])c1ccc(CSc2ncnc3c2ncn3Cc2ccccc2)cc1 +CC1C(=O)Nc2cccc3ccc(cc23)Oc2cc(ccc2C#N)Cn2cncc2CN1Cc1ccccc1 +Cc1ccc2ccc(S(=O)(=O)NC3CCN(Cc4cccc(C(=N)N)c4)C3=O)cc2c1 +CC(C)C(O)(c1ccc(-c2ccccc2)cc1)c1c[nH]cn1 +CCOC(=O)N1CC(CC(=O)O)C(c2cccc(OCCc3nc(-c4ccccc4)oc3C)c2)C1 +CCNC(=O)c1ccc(C(C2=CN(OC)C=CC2)=C2CC3CCC(C2)N3Cc2ccoc2)cc1 +CCCCNC(=O)C(C)CC(O)C1CSCC=CCSCC(N)C(=O)NC(C)C(=O)N1 +CCNC(=O)Nc1cccc(C23CCC(N(CCCN4CCN(C)CC4)C(=O)Nc4ccc(F)c(Cl)c4)C2C3)c1 +CCc1cc2c(=O)n3c(nc2s1)-c1[nH]c2ccc(OC)cc2c1CC3 +Cc1nnc(OC2CCNCC2)cc1C(=O)NCC12CC3CC(CC(C3)C1)C2 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)C1CCC1 +CCCN(CCC)C1CCc2cc(F)c3[nH]ccc3c2C1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3ccccc3F)ccc2[nH]1 +CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2ccc(CO)cc2)n1 +Cn1ccnc1-c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1 +O=C1C(C=Nc2ccc(F)cc2)=C(O)c2ccccc21 +COc1ccc(S(=O)(=O)N2c3ccccc3CCC2CCS(=O)(=O)N2CCC(NCc3ccc(F)cc3)CC2)c(OC)c1 +COC(=O)c1oc2ccccc2c1NC(=O)CSc1ccc([N+](=O)[O-])cc1 +Cc1noc(C)c1S(=O)(=O)Nc1c(N2CCC(N(C)Cc3ccc(OC(F)F)cc3)CC2)c(=O)c1=O +CC(CC1CCc2c(cccc2OCC(=O)O)C1)=NOC(c1ccccc1)c1ccccc1 +Cc1cn(CC(CC(=O)O)NC(=O)OCc2ccccc2)c(=O)nc1NCCCCNc1nc2ccccc2[nH]1 +Cc1cc(C(=O)Nc2ccc(C(=N)N3CCCCC3)cc2F)n(-c2cc3ccccc3cc2F)n1 +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(sc5c(C#N)cccc54)c3=O)CC21 +CNC1CCC(c2ccc(Cl)c(Cl)c2)c2cc(S(C)(=O)=O)ccc21 +Cc1ccc(COC(CCCCCC(=O)NO)C(=O)Nc2ccccc2)cc1 +Cc1cc(Cl)c2cccc(CN3CC(O)C(O)C3CO)c2n1 +O=C(O)CCc1ccc(OCc2cccc(-c3ccccc3)c2)cc1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(NC(=O)NC34CC5CC(CC(C5)C3)C4)cc2)CC1 +O=C(CCn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)NC3)NCCN1CCCCC1 +Cc1c(C(F)=CC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCCOc1ccc([N+](=O)[O-])cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 +Cc1cc(C)c(NC(=O)N(Cc2ccc(-c3ccnn3C)cc2)C2CCCCCC2)c(C)c1 +NC(=NCc1ccncc1)Nc1cccc(C(=O)N2CCC(C(=O)NC(CC(=O)O)c3ccc4c(c3)OCO4)CC2)c1 +COC(=O)c1cc(C=CC(=O)O)ccc1-c1ccc(O)c(C23CC4CC(CC(C4)C2)C3)c1 +CCS(=O)(Cc1cc(F)cc(Nc2ncc(F)c(-c3ccc(F)cc3OC)n2)c1)=NC#N +O=C1c2ccccc2NC(c2ccccc2F)N1c1ccc(OCCn2ccnc2)cc1 +CC(C)Nc1cc(=O)n(-c2ccccc2)nc1-c1nc[nH]n1 +COc1cccc(SCc2cnc3nc(N)nc(N)c3c2C)c1 +CC(C)(C)NC(=O)C1CCCCC1CC(O)C(Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)OCc1ccccc1 +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3cccs3)cc2)cc1 +CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(OC)cc12 +COCCOc1ccn2c(C(=O)Nc3cccc4c3c(OC)nn4Cc3ccc(C)nc3)cnc2c1 +O=C(O)c1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12 +O=C(NO)c1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c2cccc(Cl)c2)cc1 +N#Cc1cnc2ccc(NCc3ccc(S(N)(=O)=O)cc3)cc2c1Nc1ccc(F)c(Cl)c1 +Cn1c(CN2CCN(c3ccc(C(F)(F)F)cn3)CC2)nc2ccccc21 +Cc1nc[nH]c1CSCCNC(N)=NC(C)Cc1c[nH]cn1 +CN1CCC(c2ccc(Cl)cc2)C(C[S+]([O-])CCO)C1 +CC(C)Cc1cn(-c2cccc(C(=O)O)n2)c2cc(Cl)ccc12 +CC(C)c1ccccc1Sc1ccc(-c2cc(N3CCC(CCO)CC3)ncn2)cc1C(F)(F)F +Nn1c(SCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2sc3c(c2c1=O)CCNC3 +CC(Nc1ncnc(N)c1C#Cc1ccc(F)cn1)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(CNS(C)(=O)=O)c1 +CC(=NNC(N)=S)c1ccc(NC(=O)c2ccccc2)cc1 +CC1(C(=O)O)Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1 +COc1ccc(S(=O)(=O)Nc2ccc(NS(=O)(=O)c3cccc(OC)c3)c3ccccc23)cc1 +CN(C)C(=O)C(c1c(F)cccc1F)N1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)C1 +CCCCNC(=O)C(C)CC(O)C1COCC=CCSCC(NC(C)=O)C(=O)NC(C)C(=O)N1 +COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc3c(c1)C(=Cc1cnc[nH]1)C(=O)N3)CC2 +O=C(O)c1cccc(-c2csc(C3CCCCN3C(=O)COc3ccccc3)n2)n1 +CCOC(=O)C=Cc1c(OC)ccc2cc(-c3cccc(OC)c3)ccc12 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+Cc1nc(NC(C)c2cccc(-c3cnc(N4CCN(CCOCCO)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CC(C)=CCN1CCC23CC(=O)CCC2(O)C1Cc1ccc(C(N)=O)c(O)c13 +N=C(N)SCCCn1cc(C2=C(Nc3ccccc3)C(=O)NC2=O)c2ccccc21 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCN(Cc5c(C)cccc5C)C4)cc23)ccn1 +CC(C)(Oc1ccc(-n2cccn2)cn1)C(=O)NC1C2CC3CC1CC(C(N)=O)(C3)C2 +CCN1CC=C(c2ccccc2)C(C(=O)OCC2CCCCC2)C1 +COc1cccc(NN=C2C(=O)NN=C2c2cccc(OC)c2)c1 +COc1cc2c(cc1OC)CN(C(=O)C(NCc1cccs1)C(C)(C)C)CC2 +CC(c1ccccc1)N1C(=O)C2(CCCC2)C2=C1N=C(c1ccccc1)NC2N +CCCc1nc(SC(F)F)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CCc2ccccc2)cc1 +CC(=CC(=O)NC(C(=O)N1CCCC1C(=O)Nc1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 +COc1ccc(CN(C)C)cc1Nc1nccc(-c2c(-c3cccc(NC(=O)c4c(F)cccc4F)c3)nc3sccn23)n1 +NCc1ccc(Cl)cc1CNC(=O)C1CCCN1C(=O)C1(O)c2ccccc2-c2ccncc21 +CCC1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=Nc1ccccc1C +N#Cc1cccc(CNCC2CCN(C(=O)c3ccc(Cl)c(Cl)c3)CC2)n1 +N#Cc1c(N)nc2sc(C(=O)c3cccc(Cl)c3)c(N)c2c1-c1ccccc1Br +COC(=O)c1cn(C2CC(C(=O)NCc3ccc(OC)cc3)N(Cc3ccsc3)C2)nn1 +CC(=O)N1CC2CC1CN2Cc1cc2cc(Oc3nc4cnccc4s3)ccc2o1 +COc1ccc(-c2c[n+](Cc3ccccc3Cl)c3n2CCC3)cc1 +CNc1nnc(-c2ccc3[nH]cc(-c4cccc(-n5cnc(C)c5)n4)c3c2)s1 +C=C1C(=O)C23CC1CC(OC(C)=O)C2C1(C)C(OC(C)=O)CC(O)C(C)(C)C1C(=O)C3OC(C)=O +CC(=O)N1Cc2[nH]c(-c3cc(C(=O)N4CCC(c5ccc(C#N)cc5)CC4)c(C)cc3C)nc2C(C)(C)C1 +N#CCc1ccc(NCC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +CC(C)OC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1 +CCCCCc1nc(SCc2ccc(-c3ccccc3C#N)cc2)nn1Cc1ccc(-c2ccccc2-n2cnnn2)cc1 +COC1CCC(n2c(=O)c(-c3cn[nH]c3)cc3c(C)nc(N)nc32)CC1 +CC(C)C(CN1CCC(C)(c2cccc(O)c2)C(C)C1)NC(=O)C1Cc2ccc(O)cc2C[S+]1[O-] +CC(C)(C)c1ccc(C(=O)N2CCc3c([nH]c4ccc(O)cc34)C2)cc1 +COC(=N)c1nc2ccc3ncnc(Nc4ccc(OC)c(O)c4)c3c2s1 +CN(CC(CCN1CCC(O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1cccc2ccccc12 +CC(=NOCC#N)c1ccc(Sc2cc(C3(C)COC(C)(C)O3)cs2)cc1 +CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2cncn2)cc1 +Cc1nc2ccc(Nc3ncc(NC(=O)C(C)(C)O)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 +CN(C)CCN1C(=O)c2cccc3c2c(cc2[nH]c(-c4ccccc4)nc23)C1=O +O=C(O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2)n1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2c(OC(F)(F)F)cccc21 +N#Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccsc12 +C=Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 +CN1CCC2(CC1)CCN(C(=O)Cn1cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n1)C2 +CCOP(=O)(OCC)C(CC)OC(=O)COc1ccc(Cl)cc1Cl +CC(=Cc1ccc(-c2ccccc2)cc1)CN(C)Cc1ccc2c(c1)OCCC2 +c1cc(NC2CCNC2)nc(-c2cnc3ccccn23)c1 +COCCOCCOCCOC(=O)OC[n+]1ccc(NC(=NCCCCCCOc2ccc(Cl)cc2)NC#N)cc1 +CCN1CCN(c2ccc(NC(=O)c3ccccc3Cl)cc2Cl)CC1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCNC(=O)C3)cc2F)cn1 +CC(=O)NC1CCC(CCN2CCC(Oc3cccc(C(F)(F)F)c3)CC2)CC1 +CCOC(=O)c1c(Cc2ccc(OC)cc2)[nH]c2c1cc(O)c1ccccc12 +COc1cccc(-n2ncc3c(NN=Cc4ccc(O)cc4)ncnc32)c1 +O=C(OC1CC2(N3CCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2)c1ccncc1 +COC(=O)C(C)(C)NC(=O)c1ccc(C2CC2)c(Nc2ccc(Cl)cc2Cl)n1 +Cn1cnc2cc(-c3ccc(CN)cc3)nc(NC3CCOC3)c2c1=O +CCS(=O)(=O)NCC1CCC(NC(=O)CN2C(=O)CC(C)(C)Sc3ccccc32)CC1 +C#CCN(Cc1ccc2nc(C)n(C)c(=O)c2c1)c1ccc(C(=O)NCc2ccc(Cl)cc2)cc1 +CC(C)(C)OC(=O)N1CCN(C(=O)Nc2cnc3ccc(N4CCCC4c4cc(F)ccc4F)nn23)CC1 +N=C(N)c1ccc(-c2csc(N(CCC(=O)O)C3CCN(CC(=O)O)CC3)n2)cc1 +FC(F)(F)c1cncc(Cc2ccc(-c3ccccc3)nc2)c1 +O=C(Nc1ccc(Br)cc1)NC(Cc1ccccc1)C(=O)N1CCCC1 +CCOC(=O)c1ccc(-c2[nH]nc3c2C(=O)c2c(NC(N)=O)cccc2-3)s1 +CN(C)C(=N)NC1=NC(=O)C(=Cc2ccc(N3CCC(NCC(O)COc4ccccc4)CC3)cc2)S1 +CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCCCC4)cn3)nc2n(C2CCCC2)c1=O +Cn1cnc2cc(-c3ccc(OCCO)cc3)nc(N3CCC(CO)C3)c2c1=O +Cc1cc(C(=O)Nc2cccc(OC(F)(F)F)c2)nn1-c1cccc(C(F)(F)F)c1 +CN(C)C1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +COc1ccc(S(=O)(=O)N2CCCC2C(=O)Nc2cc(C)cc(C)c2)cc1OC +CC(Nc1nccc(N2C(=O)OCC2C(C)F)n1)c1cn(-c2ccc(Cl)c(F)c2)cn1 +CCc1ccc(C(=O)Nc2cc(CN3CCN(C)CC3)cc(C(F)(F)F)c2)cc1C#Cc1ccc2ccnn2c1 +COc1ccc(C(=O)N2CC3CN(c4nc5ccc(Cl)cc5s4)CC3C2)c(OC)c1 +CC(C)Sc1cc(-c2ccc(CCNCC(O)c3ccccc3)cc2)ccc1C(=O)NS(C)(=O)=O +O=C(Nc1ccc(F)cn1)c1cccnc1Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 +O=C(NO)C1C(c2ccccc2)C1c1ccc(C(F)(F)F)nc1 +COc1ccc(S(=O)(=O)N2CCCCCC2C(=O)NO)cc1 +CN(C)Cc1ccc(N2CCC(Oc3nc(-c4ccncn4)cc(=O)n3C)CC2)cc1 +CN1Cc2c(C3=CCN(C4CCC(C(=O)O)CC4)CC3)[nH]c3nccc(c23)-c2cc(F)c(F)cc21 +O=C(C1CC(N2CCN(c3ncccn3)CC2)CN1)N1CCCC1 +O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2nc3ccc(Cl)cc3s2)C2C=CC1C21CC1 +CC1=Nc2ccc(Cl)cc2C(c2ccccc2)N1Cc1ccccc1 +CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12)C(=O)NCCN1CCOCC1 +COc1ccc(C(=O)C(CC(=O)N2CCCC2C(=O)O)SC(C)=O)cc1F +CC(C)C(O)C(N)C(=O)NS(=O)(=O)C=Cc1cccc(-c2cc(N)ncn2)c1 +c1ccc2cc(NC3=NCC4(CN5CCC4CC5)O3)ncc2c1 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCCC2 +CCCCc1ccc(-c2ccc3n(c2=O)CC2CNCC3C2)cc1 +O=C(c1ccccc1)c1c(-c2ccccc2)[nH]c2ccc(Br)cc2c1=O +CCCc1c(OC(C(=O)O)c2ccccc2)c(Cl)cc2c(CC)noc12 +Cc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2C)c1C=Cc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1 +O=C(Cc1c(F)cccc1F)NC1CCN(Cc2ccccc2)CC1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1nn(C(C)C)c2ncnc(N)c12 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+CC1CN(CC2CCCC2)c2ccccc2C(C)N1C(=O)Nc1cccnc1 +CSc1ccc(C(=O)Nc2ccc(C(=O)N3CCC4(C=CCCC4)Cc4ccccc43)cc2)cc1 +CC#CCn1c(N2CCCC(N)C2)nc2ccn(Cc3ccc4cc(F)ccc4n3)c2c1=O +O=C(c1ccc([N+](=O)[O-])o1)N1CCc2ccccc2C1 +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2c(F)cccc2Cl)[nH]c1=O +O=c1cc(Cc2c(F)cccc2F)nc(NC2CCCC2)[nH]1 +COc1ccc(-c2nc(C)c(C(=O)NCc3ccc(OC(C)(C)C(=O)O)cc3)s2)cc1 +O=[N+]([O-])c1ccc(C2CC(c3ccccc3)=NN2c2ccccc2)cc1 +Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cccc(F)c4F)cc3)ccc12 +COc1ccnc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 +Nc1ccc2c(c1)OCCCN2S(=O)(=O)c1ccc(-c2cnc(C3CC3)o2)cc1 +O=C(O)CCCC=CCC1C(=O)CC(O)C1C=CC(O)COc1ccccc1 +COc1ccc(Cn2ccc3c2-c2[nH]c(=O)c(S(=O)(=O)c4ccccc4)cc2CCC3)cc1 +O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC2(C(F)(F)F)CCCC2)cc1F +COc1cccc(C2C(C(=O)Nc3ccccc3)=C(C)N=c3sc(=Cc4c[nH]c5ccccc45)c(=O)n32)c1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2=O +Nc1nc2cc(-c3nn(C4CC(=O)C4)c4ncnc(N)c34)ccc2o1 +Cc1cc2ccccc2nc1N(Cc1ccc2c(c1)CCCC2)S(=O)(=O)c1ccc(C(=O)O)cc1 +CCOc1cnc(N(C)C2CCN(c3ncnc4[nH]ccc34)C2)cn1 +Cc1nnc2sc(C(=O)NC3CN(c4ccc(F)c(F)c4)C3)c(N)c2c1C +COc1ccc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)on3)cc2)cc1 +CCCc1c(OCCCOc2ccc(CC(=O)O)cc2Cl)ccc2c(C(F)(F)F)noc12 +CC1=C(C#N)C(c2ccc(F)cc2F)C(C(=O)OC(C)(C)C)=C(C)N1 +c1cc(-c2cn(CCCN3CCOCC3)c3cnccc23)ccn1 +COc1ccc(-c2nn(-c3ccccc3)cc2C(=O)NN=Cc2ccc([N+](=O)[O-])o2)cc1 +COc1ccc(C(=O)NCCOCCNc2nc(Nc3ccc(O)cc3)nc(Nc3ccc(C(=O)NCc4ccccc4)cc3)n2)cc1 +CN(CC(CCN1CCC(O)(CCCc2ccccc2)CC1)c1ccccc1)S(=O)(=O)c1cccs1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCCNC2)n1 +CC(C)CC1CNC(=O)c2cc3cnc(Nc4ccc(N5CCN(C)CC5)cn4)nc3n21 +CCS(=O)(=O)c1ccc2c(c1)nc(CC(C)C)n2CC1CCOCC1 +CCn1nc(-c2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 +COc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(=O)C(NC(=O)C(F)(F)F)c1ccccc1)CC2 +COC1=C(CCNC(C)=O)c2nc3ccccc3c3ccnc(c23)C1=O +Cc1ccc(-c2noc(CCCCCCC(=O)Nc3ccccc3N)n2)cc1 +c1ccc2nc(-c3ccc(N4CCOCC4)cc3)ccc2c1 +CON=C(COCc1ccc2ccc(C(F)(F)F)nc2c1)C(CCN1CCC(O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1 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+O=c1cc(OCc2ccc3ccccc3c2)ccn1-c1ccc(OCCN2CCCC2)cc1 +COC(=O)C1C(OC(c2ccc(F)cc2)c2ccc(F)cc2)CC2CCC1N2C +Nc1nc(-c2ccc(CCN3CCN(c4cccc5ccccc45)CC3)cc2)cs1 +CNCc1ccc(-c2cc3cccc4c3n2CCNC4=O)cc1 +N#CN=C1N(CCCCCCCOc2ccc(Cl)cc2)C(=O)C(c2ccccc2)N1c1ccncc1 +Cc1ccc(-c2ccc(Cc3nnn(C(=O)N(C)C)n3)cc2)cc1 +O=C(NC(c1cnc(Cl)c(Cl)c1)C1CCNCC1)c1ccc2cnccc2c1 +COc1c(C#N)cccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 +O=C(Nc1nnc(SCc2ccccc2)s1)c1ccc(F)cc1 +COc1cc(CNC(=O)C(CC2CCCCC2)NC(=N)NC(=O)Cc2ccc(OC)c(OC)c2)ccc1F +CC(C)(C)OC(=O)NC(CCCCN)C(=O)Nc1ccc(C(=O)O)c(-c2ccc(O)cc2)c1 +CN1CCC(c2c(-c3ccc4nc(NC(=O)c5ccncc5)cn4n3)c(-c3ccc(F)cc3)nn2C)CC1 +Cc1cc(COc2ccc(C(=O)NC3(CC(=O)NO)CCN(S(C)(=O)=O)CC3)cc2)c2ccccc2n1 +CCN(CC)C(=O)C=C(C)c1ccc(OCc2c(F)cccc2F)c(OCC(=O)O)c1 +COCCOc1ccc(S(=O)(=O)C2CCN(c3cc(C(F)(F)F)nc(C#N)n3)C2)c(Cl)c1 +COc1ccc(C=CC(=O)N2CC(CCl)c3c2cc(O)c2ncccc32)cc1O +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2c(c1)C=NC2CCCO +COc1ccc(C(=O)Nc2cc(OC)ccc2NC(=O)c2ccc(N3CCCN(C)CC3)cc2)cc1 +O=C1CC(c2ccc(CC(NS(=O)(=O)c3ccccc3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 +COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccccc3Cl)oc12 +CC(C)CN(CC(C)C)C(=O)c1cncc(C(=O)NC(CC(=O)O)C(=O)CSCc2ccc(F)cc2)c1 +CCc1c(C(=O)NCCc2ccc(N(C)C)cc2)oc2ccc(Cl)cc12 +Cn1c(C(=O)Nc2ccccc2COc2ccc(OCC3CCNCC3)cc2)cc2sccc21 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(CC(F)(F)F)C1 +CCCC(CCC)n1cc2c3c(nc(C)cc31)N(c1ccc(OC)cc1C)CC2 +O=C(Cc1cccc(NCC(F)(F)c2ccccn2)[n+]1[O-])NCc1cc(Cl)ccc1-n1cncn1 +CSc1nn2cc(-c3nc4c(OCC5CCCN5C(=O)C(NC(=O)c5ccccc5)c5ccccc5)cccc4o3)nc2s1 +Cn1cc[n+](CC(O)(P(=O)([O-])O)P(=O)(O)O)c1 +CC(C)COc1ccccc1-c1cc(-c2ccc(Cl)cc2)[nH]c1-c1ccncc1 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCC1CCC(N)CC1 +COc1cc(C(=O)N2CCCCC2)c(NS(=O)(=O)c2cccc3nsnc23)cc1Cl +CCN(CC)c1ccc(-c2cn3c(=O)c4ncn(C5COC(CO)O5)c4nc3[nH]2)cc1 +CC1(C)C(NC(=O)OCCCc2c[nH]cn2)C1(C)C +O=C(NO)C1Cc2ccccc2CN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +COc1cccc(-c2cc3c4c(cccc4c2)C(=O)N(CCN(C)C)C3=O)c1 +Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(C(F)(F)F)c3)cc2)no1 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+COc1ccccc1-n1nc2c(c1C(C)C)C(CC(O)CO)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O +Cc1nccn1-c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2ccc3onc(N)c3c2)c(C#N)c1 +CNc1nccc(CNc2ccccc2C(=O)Nc2ccc3c(c2)OC(F)(F)O3)n1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2cccc(C(=O)NO)c2)CC1 +O=C(Nc1ccccc1)c1cccn2c(=O)cc(N3CCOCC3)nc12 +O=C1Cc2cc(C#CCCN3CCC(Cc4ccccc4)CC3)ccc2N1 +Cc1ccc(S(=O)(=O)N(C)C2(C(=O)NC3C4CC5CC3CC(C(N)=O)(C5)C4)CCC2)cc1Cl +Cc1ccc(S(=O)(=O)N2CC(c3ccc(Br)cc3)C(C(=O)C3CO3)=N2)cc1 +COCCCn1cc(C)c2ccc(C(C)N(C(=O)C3CNCCN3)C3CC3)cc21 +Cn1c2ccnc(N3CCOCC3)c2c2ncnc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c21 +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc2c(c1)OCO2 +COc1ccc(OC(C)(C)C2OCC(CC=CCCC(=O)O)C(c3cccnc3)O2)cc1 +CC1(C)C=C(COc2ccc(-c3nc4c(C(N)=O)cccc4[nH]3)cc2)C(C)(C)N1 +O=C(NC(Cc1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(C2CCCCC2)CC1)C1CCc2ccccc2N1 +Cc1ccc(C(NC(=O)Cc2ccccc2)NC(=O)Cc2ccccc2)cc1 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cncc(NC(C)C)c1 +Cc1cc(COc2ccc(S(=O)(=O)N(C)C3CCCC3C(=O)NO)cc2)c2ccccc2n1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCN(c3ccccc3C(F)(F)F)CC2)cc1 +NCC(O)CNC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +Cc1ccc(C(=O)N(CCCN)Cc2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)cc1 +Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2CC(Cl)c1ccccc1 +CC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cnn(C)c3)nc12 +CC1NC(=O)C(c2ccc(F)cc2)=C1c1cc(Cl)c2c(c1)NC(=O)CO2 +COc1ccc(C(=O)NC(CC(=O)O)c2ccc(C)cc2)nc1-c1cc(Cl)ccc1Cl +Cc1c(-c2nnc(C(C)(C)C)s2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +NS(=O)(=O)Oc1ccc2c(=O)c(C3CCCCC3)coc2c1 +O=c1[nH]ccc2ccc(OCCCN3CCN(c4cccc5sccc45)CC3)cc12 +N#Cc1ccc(-c2n[nH]c3c2Cc2ccc(OCCCc4cccs4)cc2-3)cn1 +COc1cc(OC)cc(-c2cc3cc(OC)c(OC)cc3c(N)n2)c1 +Cc1cc(C(=O)O)c2nc(-c3ccc(-c4cccc(F)c4F)cc3)[nH]c2c1 +O=C(O)CN1C(=O)C(NC(CSCc2ccccc2)C(=O)O)CCc2ccccc21 +COc1ccc(Nc2cnc(Nc3ccc(OC)nc3)c(-c3nc(C)nc4[nH]cnc34)c2)cc1 +Cc1cnc(C)c(-c2ccc(N(Cc3ccccc3)C(=O)c3ccc(O)cc3O)cc2)n1 +O=C(CC1CCOCC1)Nc1ccc(NC(=O)N2Cc3ccc(CO)cc3C2)cc1 +CC(O)C1(CNC(=O)c2cc3cc(C#N)ccc3n2Cc2cccc(OC(F)(F)F)c2)CCCC1 +CC(N=O)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 +Cc1cccc(Cl)c1Nc1nc2ccc(N3CCCCC3)nc2n2cncc12 +CS(C)(=O)=Nc1cc(C2CC2)c2c(Nc3ccc(F)cc3OC(CF)CF)ncnc2c1 +Nc1nc(-c2ccccc2)cn2cc(-c3ccco3)nc12 +CCOC(=O)c1c(Cc2cccc(Br)c2)[nH]c2c1cc(O)c1ccccc12 +Cc1ncc(Cl)cc1C(=O)NC1CCC(CN2C(=O)C(C)(C)c3cccc(Cl)c32)CC1 +O=C(O)COc1cccc2c1CCC(COC(=O)N(c1ccccc1)c1ccccc1)=C2 +CCC(=Cc1cc(C=CC(=O)NO)n(C)c1)C(=O)c1ccccc1 +Oc1ccc(C2(O)CCN(CCCCc3ccccc3)CC2)cc1 +CCC(C)C(N)C(=O)NS(=O)(=O)CC(=O)NC1(C(=O)OC)C(O)CC2C(C(N)=O)=CN(C)CC21 +Cn1cnc2c(NCc3ccc(-c4ccccc4)cc3)nc(NC3CCC(N)CC3)nc21 +CC1=C(c2nc3cc(Cl)ccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CCC=CCNc1cccc(C(O)CNC(C)Cc2c[nH]c3c(OS(C)(=O)=O)cccc23)c1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2ccc3ccncc3c2)c2cc[nH]c2c1=O +COCCNc1cncc(-c2cn(-c3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3C)nn2)c1 +O=C(c1ccccn1)C1CCN(CC(=O)N(Cc2nc3c(c(=O)[nH]2)COCC3)CC2CC2)CC1 +Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(=O)NCCc1ccc(OC(C)(C)C(=O)O)cc1 +Cc1ccccc1N1CCN(C(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)CC1 +CCCCN(CCCC)c1cc(C)nc2c(-c3ccc(Cl)cc3)nn(C)c12 +COC(=O)Nc1ccc(-c2ccnc(C(Cc3ccccc3)NC(=O)C=Cc3cc(Cl)ccc3-n3cnnn3)c2)cc1 +O=S(=O)(NC1CCN(CCOc2cccc3c2CCCC3)C1)c1cccs1 +CC(=O)Nc1cccc(N(C)CCCN2CCN(c3ccccc3)CC2)c1 +COCc1cc(OC)c(-c2csc3c(N(C(C)C)C4CCOCC4)c(OC)nn23)c(OC)c1 +Nc1ncc(-c2cnn(C3CCCNC3=O)c2)c2scc(-c3ccc(Oc4ccccc4)cc3)c12 +CC(C#N)NC(=O)C(C)c1ccc(OC2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)C=Cc2cccc(I)c2)CC1 +CCN1CCN(C(N=O)c2ccc(C#CC3(CN4Cc5ccc(OC)c(F)c5C4=O)NC(=O)NC3=O)cc2F)C(C)C1 +Cn1nc(OC2c3cc(C#N)ccc3OC(C)(C)C2O)ccc1=O +COc1ccnc(N2CC3CN(C(=O)c4cc(F)ccc4-c4ncccn4)CC3C2)n1 +Cc1c(Cc2ccccc2)nnc(N2CCC(C#N)(c3ccc(C(C)(C)O)cn3)CC2)c1C +CS(=O)(=O)NC(=O)c1ccc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)cn1 +CN1OC2(N=C1N)c1cc(C#CC3CC3)ccc1CC21CCc2ccccc2CC1 +COc1ccc(CC(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +Cc1ccc2c(c1Cl)NC(=O)C2(c1ccc(O)cc1)C1CCCCCC1 +CC1(C)OC(=O)c2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)s3)cc21 +CCN(Cc1ccccc1)C(=O)c1nc(-c2ccccc2F)c2ccccc2n1 +O=C(O)CCc1ccc(C#Cc2cc(Cl)nc(Cl)c2)cc1 +CC(C)Oc1ccc(Nc2ncc(NC(=O)N3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F +CCCCOP(=O)(OCCCC)OC(c1ccccc1)C(F)(F)F +O=C(NC1CCCCC1)OCc1c2ccccc2cc2ccccc12 +O=C(c1ccc(F)cc1)C1CCN(C2CN(C(=O)c3cccs3)CCC2O)CC1 +COc1cccc(-c2ccc(CN3CCC4(CC3)C(=O)N(c3cccc(OC)c3)C(=O)N4Cc3ccccc3F)cc2)c1 +COc1cc(Sc2ccc3c(N)c(OC)ccc3n2)cc(OC)c1OC +COc1cc(C(=O)N2CCC2c2noc(-c3cccc(Cl)c3OC)n2)c(-n2nccn2)cc1Cl +O=C1C(=O)N(Cc2ccnc(F)c2)c2ccc(S(=O)(=O)N3CCC3COc3ccccc3)cc21 +Cc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)cccc21 +Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1 +O=C1Nc2c(ccc(F)c2F)C1(c1ccc(O)cc1)C1CCCC1 +CSc1ccc(Cn2cnc3c(N(C)C)nc(C(F)(F)F)nc32)cc1 +CC(C)c1cc(Nc2cc(N3CCN(C)CC3)nc(NCc3cc(-c4ccc(F)cc4)no3)n2)[nH]n1 +CC(C)(C)CNC(=O)c1ccc(Br)c(S(=O)(=O)N2CCOCC2)c1 +Oc1nc2cccc(N3CCN(Cc4cccc(-c5ccc(F)cc5)n4)CC3)c2o1 +Cn1ncc2c(CN3CCCC4(CCN(c5cnc6ccccc6n5)CC4)C3=O)cccc21 +COc1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(C(=O)NCc6ccc(OC)cc6)cnc45)cccc3c2)cc1 +Cc1ccccc1C(=O)Nc1cc2c(cc1N1CCCCC1)n(C)c(=O)n2C +CN1C(=O)Cc2ccc(-c3cc(F)c(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3)cc21 +Cc1cc(-n2cccc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +CN(C(=O)CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)C1CCCCC1 +CCn1c(=O)n(CC)c2cc(-c3[nH]ncc3-c3cccc(C)c3)ccc21 +Cc1noc(C)c1-c1ccc2c(c1)C(C1CCCCC1)(N1CCN(C)CC1)C(=O)N2 +CC(C)c1cccc(NC(=O)c2cccc(N3CCc4c(cncc4C(=O)NCCCN4CCOCC4)C3)c2)c1 +Cc1cccc2nc3c(C(=O)NCCCN(C)CCCNC(=O)c4cccc5cc6c(C)cccc6nc45)cccc3cc12 +CCN(C(=O)O)S(=O)(=O)N1CCC(c2cc3c(-c4cncc(NCc5ccccc5)n4)ccnc3[nH]2)CC1 +CN(C)C(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C +Nc1ccnc(Oc2cc(C(F)(F)F)ccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)n1 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)Nc3ccccc3F)CCC12 +CC(C)N1CCCN(C(=O)c2ccc3c(CN4CCOCC4)cn(C)c3c2)CC1 +O=[N+]([O-])c1ccc(OCC(COc2ccc([N+](=O)[O-])cc2)OC2OC(CO)C(O)C(O)C2O)cc1 +O=C(O)c1cc(-c2csc(C(O)C(F)F)c2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1 +CCC(C)(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(N)=O +c1ccc(Nc2nc(-c3ccccc3)nc3ncccc23)cc1 +CCc1ccc(Cc2c[nH]c3cccc(OC4OC(CO)C(O)C(O)C4O)c23)cc1 +CC(=O)C(C)N1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +COc1ccc(CCCCNCCOc2cc(F)cc3c2OCCC3OC)cc1 +COc1ccc2ccc(=O)n(CC(O)C3CCC(NCc4cc5c(cn4)OCCO5)CO3)c2n1 +CNC(=O)c1cn(C)c2c1C(C)(C)Cc1cnc(Nc3cccc(CN4CCN(C)CC4)c3)nc1-2 +O=C1CCCC2=C1C(c1ccc(F)c(Cl)c1)C1=C(CCS1(=O)=O)N2 +O=C(C(NS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1)c1ccccc1)N(Cc1ccco1)Cc1cccs1 +N#Cc1cc(S(=O)(=O)Nc2nncs2)ccc1Oc1ccc(Cl)cc1-c1cn[nH]c1 +C=CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 +FC(F)c1ncn2c1Cn1ncnc1-c1cc(Br)ccc1-2 +CCC(C)C(NC(=O)C1CCCc2ccccc21)c1nc(C(=O)NC(CCCNC(=N)N)C(=O)O)co1 +CCCS(=O)(=O)NCc1ccc(CC(=O)N(C)C(CN2CCC(O)C2)c2ccccc2)cc1 +O=C(NCCCCN1CCN(c2ccccc2C(F)(F)F)CC1)Oc1ccc(-c2ccccc2)cc1 +CCCC[S+]([O-])c1sc2nc(-c3nccs3)cc(-c3ccc(CNC(=O)NCC)cc3)c2c1N +CCN(CC)c1nc(Nc2ccc(Cl)cc2)c2cn[nH]c2n1 +COc1ccc(CN(C(=O)n2cnc(S(=O)(=O)C3CC4CCC3C4)n2)C(C)C)cc1 +Cc1nnnn1-c1ccc(C(=O)NCc2cccc(C(=O)Nc3nc4c(s3)CC(N3CCOCC3)CC4)c2)cc1 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+CCCCNC(=O)C(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +CC1(C)C(C(=O)c2cn(CCN3CCCC3=O)c3ccccc23)C1(C)C +CCCOC(=O)c1ccc(-c2ccc(C3COC4(C=CC(=O)C=C4)O3)cc2)cc1 +CN1CCC(Nc2cc(Nc3cc(C4CC4)[nH]n3)nc(-c3ccccc3)n2)CC1 +Nc1ncnc2c1c(Oc1cccc(Cl)c1)nn2CC1CCNCC1 +CCCc1cccc(-c2cc(NC(=O)C3(C)CNC(=O)C3)nn2-c2ccccc2)c1 +CCOC(=O)c1c(-c2cccc(Br)c2)[nH]c2cc(OC)ccc2c1=O +Nc1ccccc1NC(=O)CCCCCNC(=O)c1cnc2ccccc2c1 +Cn1c(OC2CCCN(c3cccc(F)c3)C2)nc(-c2ccncn2)cc1=O +COc1cccc(C(CC(C)C)NC(=O)c2cc(COc3ccccc3)ccc2CCC(=O)O)c1 +Cn1cnc2cc(-c3ccc(N4CCS(=O)(=O)CC4)cc3)nc(N3CCC(CO)C3)c2c1=O +Cc1nn(Cc2ccc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)cc2)c(C)c1CC(=O)O +COC(C(=O)NC1CCC(OC(=O)C2CCCCC2)CNC1=O)C(O)C(O)C(O)C=CC(C)(C)C +Cc1nc(N2CCCCC2)c2nc(C3CCCCC3)cc-2[nH]1 +O=C(NCc1ccc(F)cc1)N1CCN2C(=O)c3ccncc3C12c1ccc(Cl)cc1 +Cc1c(O)nc(SCc2ccccc2)nc1Cc1c(Cl)cccc1Cl +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCCCCCCCCCC(=O)O)C(=O)O)cc1 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1Cc1ccc2ccccc2c1 +CN1C(=O)NC(=O)CC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c2ncccc12 +O=C1CCCCN1CCN(C1(C(=O)O)CC1c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 +NC(C(=O)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1)c1ccccc1 +Cc1nc2cccc(-c3[nH]c4c(c3C)C(=O)NCC4)c2nc1NC(C)(C)C +CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O +CS(=O)(=O)c1ccc(-c2coc(=O)n2-c2ccccc2F)cc1 +CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3CCc2ccccc2)c2cccc(OC)c2)cc1 +CCOC(=O)C1=C(Nc2ccc(Cl)c(C(F)(F)F)c2)SCC1=O +CCCCCCCc1ccc(NC(=O)C2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 +CCC(=O)N1CC(OC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(c2ccc(F)cc2)C1 +CCc1nc2c(-c3ccc(OC)cc3C)ncnc2n1C(C1CC1)C1CC1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c3)c2cc1OC +Cc1cccc(CNC(=O)Nc2nc(-c3ccncc3)cs2)c1 +CCCOc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CCCOCCn1c(=O)c(NCC(=O)N2CCN(C)CC2)nc2cnc(-c3ccc(OC)nc3)cc21 +O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)c1cccc(C(F)(F)F)c1 +CC12CCC(NC(=O)C3CC3)CC1=CCC1C2CCC2(C)C(n3ccnc3)=CCC12 +COc1cc(F)c(-c2nc(C(=O)Nc3cnccc3C3CC(N)CC(C)(C)C3)ccc2F)c(F)c1 +CN1C(=O)CC(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c3ncccc23)NC1=O +COC(=O)c1ccc(C(=O)N2CC3CN(CCC(NC(=O)C4CCCC4)c4ccccc4)CC3C2)cc1 +O=C(C=Cc1ccc(O)c(CN2CCCCC2)c1)c1ccc(C(F)(F)F)cc1 +NNC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccc(F)cc1 +COC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CC(=O)OC(C)(C)C)c1 +CNC(=O)c1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 +CCCCCC1(CCCCC)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)=C(O)O1 +COC(=O)C1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2 +CCCCN(Cc1cc(Cl)c(OC)c(Cl)c1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CCCCCCCCCCCCc1nnn(C(C(=O)Nc2c(C(C)C)cccc2C(C)C)c2ccccc2)n1 +Cc1ccccc1NC(=O)NC1CCCCC1CN1CCCC(Cc2ccc(F)cc2)C1 +CNC(=O)c1c(-c2ccc(F)cc2)nc2sc(-c3cc(C(=O)NC(C)(C)c4ccccc4)ccc3OC)cn12 +O=C1Nc2cccnc2N(C(=O)CN2CCN(CCCCCCCCCCNC(=S)Nc3cccc(N=C=S)c3)CC2)c2ccccc21 +O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2ccccc2c1 +c1ccc(CCCCN2C3CCC2c2c(n(-c4ccccc4)c4ccccc24)C3)cc1 +COc1cc(C2C(C#N)=C(N)Oc3cc(O)ccc32)cc(Br)c1OC +COc1ccc(C2CC(=O)N(c3ccncc3)C2)cc1OC1CCCC1 +COc1cccc(OC)c1CNC(=O)c1cc2cc(CC(C)NCC(O)c3ccc(O)c(CO)c3)ccc2n1Cc1ccccc1 +Cn1cc(-c2ccc3nc(NC(=O)c4ccccc4)cn3n2)c(-c2ccc(F)cc2)n1 +CCC(NC(=O)c1cc(C(=O)NCc2ccccc2C#N)n2c1COCC2)c1ccccc1 +Cc1n[nH]c2c1C(c1ccc(-c3ccc(Cl)cc3)o1)C(C#N)=C(N)O2 +CCC(C1=C(O)OC2CCCCC2C1=O)c1cccc(NS(=O)(=O)c2ccc(C#N)cc2)c1 +CC(=O)N1CCC(Nc2ncnc3c2ncn3C2OC(CO)C(O)C2O)C1 +COc1ccc(CCNC(C)COc2c(C)cc(Cl)cc2C)cc1OC +CN1CCN(CCNc2nc3cc(Cl)c(C#N)cc3nc2-c2ccccn2)CC1 +Cc1cccc(C(=O)Nc2cccc(Oc3cncnc3)n2)c1 +CCOC(=O)c1ccc(NCc2cc3c(cc2O)CCCO3)cc1 +CC(C)CCN(C(C(=O)NO)C(C)C)S(=O)(=O)c1ccc2cc(OCC(C)C)ccc2c1 +Clc1ccc(-c2cc(CNC3CCCC3)nn2-c2ccc(Cl)cc2Cl)cc1 +Fc1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)nc1 +C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2)cc1 +O=C(Nc1ccccc1)Nc1nc2ccccc2n2c(=O)n(-c3ccc(Cl)cc3)nc12 +Nc1nc(N)c(C(C[N+](=O)[O-])c2ccccc2)c(N)n1 +O=C1c2ccc(F)cc2CC1CCN1CCc2ccccc2C1 +O=c1cc(-c2ccc(F)cc2)c2cc(Sc3cc(F)cc(C(O)(C(F)(F)F)C(F)(F)F)c3)ccc2o1 +Cc1cc(C)c2sc(C(=O)N(C)C)c(-c3ccc(CCNc4ncccn4)cc3)c2c1 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+Cc1cc(Nc2cccc(NC(=O)c3ccc(Nc4ccnc5ccccc45)cc3)c2)nc(N)n1 +CC(C)Nc1nc(-c2ccc(NCCN3CCOCC3)nc2)cc2ncn(C)c(=O)c12 +O=C1N(Cc2ccccc2)c2ccccc2C1(O)c1ccc2c(c1)OCO2 +COCC(Cc1cccc(C(=N)N)c1)C(C=Cc1ccccc1)NC(=O)c1ccc(-c2ccccc2)cc1 +COc1ccccc1N1CCN(CCCOc2cc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)ccc2OCc2ccccc2)CC1 +O=C(Nc1cc(-c2cccnc2)cc(C(F)(F)F)c1)Nc1nccs1 +COCC(NC(=O)Nc1cc2[nH]nc(N3CCOCC3)c2cn1)c1ccccc1 +CC(C)N1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +CCCOc1c(Cl)cc(Cl)cc1CNC1CCCN(c2nc3nc(Cl)ccc3[nH]2)C1 +COc1cc(N2CCNCC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)n2cc(C(=O)NCC(F)(F)F)nc2c1C(N)=O +CN(C)CCn1cc(C(=O)N2CC(O)CC2C(=O)NC(Cc2ccccc2)C(=O)N(C)Cc2ccccc2)c2ccccc21 +O=c1[nH]c2ncc(-c3ccc4[nH]cnc4c3)nc2n1CC1CCOCC1 +CCCc1c(OC)c(NC(=O)CC)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 +CS(=O)(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(F)cc2)CC1 +CCC(C(=O)Nc1ccc(-c2nsc(=O)[nH]2)cc1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O +NCC1CN(c2ccc3nc(C(F)(F)F)nn3n2)C(=O)CC1c1cc(F)ccc1F +COC(=O)CC1N=C(c2ccc(-c3ccccc3OC)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +CCN(CC)C1CCS(=O)(=O)c2sc(S(N)(=O)=O)cc21 +COc1cccc2cc(C(=O)NCCCCCCCNc3c4c(nc5ccccc35)CCCCC4)oc12 +Cc1cccc2ccc(N3CCC(C(=O)NC4CCCC(CO)C4)C(C)(C)C3)nc12 +Cc1noc(NS(=O)(=O)c2cccc(-c3ccccc3)c2)c1Cl +OC1=C2C(=Nc3ccnn3C2c2cccc(Br)c2)CCC1 +Cc1c(C(O)CN2CCN(CC(O)c3ccc4c(c3C)COC4=O)C(C)(C)C2)ccc2c1COC2=O +O=C1NC(COC(=O)c2cccc3cnccc23)CNc2cn(CCc3ccccc3)nc21 +CC(C)c1cc(-c2ccccc2)cc(C(C)C)[n+]1CC(=O)OCCOc1ccc2nc(S(N)(=O)=O)sc2c1 +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C(=O)NC2CC2)o1 +Cc1nc(N2CCC(C)CC2)c2c(C)c(C(=O)Nc3ccc(C(F)(F)F)cc3)sc2n1 +O=C(C1CC2CCC1C2)N1CC(c2nc(-c3cccc(Cl)c3)no2)C1 +CC(=O)Nc1cccc(-c2nc(C3CCCCN3C(=O)COc3ccccc3)n(C)n2)c1 +C=C1CC(OC(=O)C(C)(O)CI)C2C(=C)C(=O)OC2C2C1CC(O)C21CO1 +COc1cccc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)N(C)C +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCCS(N)(=O)=O)[nH]c3ccc(Cl)cc23)c1 +O=C(O)CCCC=CCC1C2CCC(C2)C1NS(=O)(=O)c1ccc2oc3cc([N+](=O)[O-])ccc3c2c1 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+COc1cc(Nc2c(C#N)cnc3cc(OCCCCN4CCOCC4)c(OC)cc23)c(Cl)cc1Cl +O=c1cc(-c2ccccc2)ncn1CCCCCN1CCN(c2ccccc2)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(OC(C)C)nn3c2)c1F +CCc1c(Sc2cc(C)cc(C)c2)n(OCc2ccccc2)c(=O)[nH]c1=O +COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4ccc(Cl)cc4)CC3)O2)CC1 +CSc1cccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Br)cc2)c1 +NC(=O)c1cccc2c(NCc3cccc(Nc4nc5ccc(C(F)(F)F)cc5[nH]4)c3)ncnc12 +O=S(=O)(c1ccc2c(c1)C1C3CCC(C3)C1C(c1ccccc1)N2)N1CCOCC1 +Cn1cc(Nc2nccc(NC3C4C=CC(C4)C3C(N)=O)n2)cn1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3)cc2)cc1 +COc1ccc(CCN2CCN(c3ccccn3)CC2)cc1OCCc1ccccc1 +Cc1nn(Cc2ccc(C#Cc3ccc(C(F)(F)F)cc3)cc2)c(C)c1CC(=O)O +CCOC(Cc1ccc(OCC=Cc2cc(OC3CCCC3)cc(OC3CCCC3)c2)cc1)C(=O)O +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(Cn2cccn2)CN1 +COc1cc(-c2ccc3ncc4nnn(C(C)c5ccc(F)cc5)c4c3c2)ccn1 +Cc1ccc(S(=O)(=O)N2CC3(CC2C(=O)NN=Cc2ccccc2[N+](=O)[O-])SCCS3)cc1 +Cc1ccc(S(=O)(=O)Nc2nc(-c3ccc(Cl)c(Cl)c3)cs2)cc1 +N#Cc1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(C#N)cc4)s3)s2)cc1 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+O=c1[nH]c(=O)n(CCc2cccc(C(F)(F)F)c2)nc1O +O=C(O)CCCc1ccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)cc1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccc(OC)nc3)ccc21 +CNC(=O)c1nc2ccc(CCNC(=O)Nc3cc(C(F)(F)F)ccc3OC)cc2[nH]1 +O=CC(NS(=O)(=O)c1ccccc1Oc1ccc(C2CCCC2)cc1)C(=O)O +CCN(CC)CCCC(C)Nc1cc(CCCCCCCCCCCCc2cc(NC(C)CCCN(CC)CC)c3ccccc3n2)nc2ccccc12 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CC(n5cccn5)C4)ncn3)c2c1 +CC(=NOC1CCNCC1)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +CC(C)(C)OC(=O)c1ncn2c1C1CCCN1C(=O)c1cc(-c3ccco3)ccc1-2 +Cn1cnc(CS(=O)(=O)c2ccc(Br)cc2)c1[N+](=O)[O-] +Cc1cc(SCc2nc(-c3ccc(OC(F)(F)F)cc3)ns2)ccc1OC1(C(=O)O)CCCC1 +CC(C)CC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)O +CCC(C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(C)cc1 +NC(=O)Nc1sc2c(c1C(N)=O)CCc1nn(C3CCCN(Cc4ccc(F)cc4F)C3)cc1-2 +NC(=O)c1cccc2c(NCc3cccc(Nc4nc5ccccc5s4)c3)ncnc12 +O=C(NC1C2CC3CC(C2)CC1C3)N1CCCC(c2ccccc2)C1 +CN1CCN(c2cc(Cl)c3nc(Nc4ccc(Br)cn4)[nH]c3c2)CC1 +CC1(C(=O)O)CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(N)C(C)(C)C5CCC43C)C2C1 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+Nc1[nH]cnc2c(C3NC(CSc4cccc(Cl)c4)C(O)C3O)cnc1-2 +CC(C)CC(NC(=O)C(CC(C)C)NC1=CC(=O)c2ccccc2C1=O)B(O)O +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(N(C)Cc2ccc(C(=O)O)cc2)c(C(F)(F)F)n1 +Cc1ccc2c(NCc3ccccc3)c3c(nc2c1)CCCC3 +Cn1nc(C(C)(C)NC(=O)C2C3CNCC32)c2ccccc21 +Cc1cccc(NC(=O)c2ccc(-c3ccc(F)cc3)c(C#N)c2)n1 +Oc1ccc2c(c1)C1c3cc(O)ccc3C(C2)N2CCCC12 +COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(Cl)cc2)cc1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CC3CC1CC(c1ncc[nH]1)(C3)C2 +CCN1C(=O)c2c(nc(Br)n2Cc2ccc(O)cc2)N2CC(Cc3ccccc3)N=C12 +O=C(OC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5)c1cc2ccccc2cn1 +CC(C)CN(CCCN1CCN(CCCNCc2ccncc2)CC1)CC(C)C +CCCCn1nc(Cc2ccccc2)cc1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2ccccc2)CC1 +O=C(Nc1cc2ccccc2cc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(Cl)ccn1 +COc1ccc2c(c1)c(Cc1cccc(OC(C)(C)C(=O)O)c1)c(C)n2C(=O)c1ccc(Cl)cc1 +O=C(C=C(O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccccc2F)c1=O)C(=O)NC1CCCC1O +Cc1ccccc1-c1c(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n(C)c(=O)c2ccccc12 +CCC(NC(=O)c1cc(C(=O)NC(CC)c2ccccc2)n2c1SCC2)c1ccccc1 +CC(C)(Nc1cccc(F)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 +c1ccc2c(c1)C1CC(c3ccsc3)(c3ccsc3)C2c2cccc[n+]21 +Brc1cc(CN2CCCCC2)cc(Br)c1OCCCN1CCCCC1 +O=C(NC1CCC(CCN2CCC(c3noc4cc(Cl)ccc34)CC2)CC1)C(O)C(F)(F)F +CN1CCC(S(=O)(=O)c2ccc3nc(NC(=O)NC(=O)c4cc5c(cc4Cl)CCN5C)sc3c2)CC1 +OC(CNCC1CCN(CCC(F)(F)F)CC1)COc1cccc2[nH]c3ccccc3c12 +COc1ccccc1N1CCN(CCn2c(=O)[nH]c3sccc3c2=O)CC1 +Cc1cccnc1-c1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 +CN1CCC(O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)c(COc4ccccc4Cl)n2CCO3)C1=O +O=C1NCCCCC1N(Cc1cnc2ncccc2c1)S(=O)(=O)c1ccc(Cl)cc1 +CCNc1nnc(-c2cnc(N3CCN(C4CCN(C(=O)c5ccc(Cl)nc5N)CC4)C(CC)C3)c(C3CC3)n2)o1 +CCOC(CCc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 +COC(=O)CN1Cc2c(nc(C)c(CN)c2-c2ccc(Cl)cc2Cl)C1=O +O=S(=O)(c1cccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)c1)N1CCCCC1 +O=C(Nc1cc(CO)ccn1)Nc1cccc2c1C1CCCCN1C2=O +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3ccc(F)cc3F)c(F)c2)CC1 +CC(C)CC(C=O)NC(=O)C(NC(=O)c1cc(C=O)c[nH]1)C(C)C +CC(C)n1nc(C(=O)NC2CC3CCC(C2)N3CCN2CCN(S(C)(=O)=O)CC2)c2ccccc21 +CC(=O)c1cc(NC(=O)NCCCC2CC(Cc3ccc(F)cc3)CCN2C(C)=O)cc(C(C)=O)c1 +CCCS(=O)(=O)NC(=O)c1cc(COc2ccc(-c3ccc(OC)cc3)cc2)c(C)o1 +Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nc5)cc4=O)nc31)CN1CCCC1C2 +CC(C)(C)c1ccc(Cc2cc3c(cc2Cl)COC32OC(CO)C(O)C(O)C2O)cc1 +O=C(Nc1n[nH]c2nc(-c3cccc(O)c3)ccc12)C1CC1 +CC(c1ccc(-c2ccc(=O)n(C)n2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2)OC1=O +CCCCCCCCCCC1(C(=O)Nc2c(C)c(Cl)c(C)c3c2OC(C)(C)C3)CCCC1 +O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(COc2cnc(C3CC3)c(Cl)c2)cc1F +CN(C)CCN1C(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +N#CC1(c2cccc(C(=O)Nc3cccc(Nc4ccnc(NC(=O)C5CC5)c4)c3)c2)CC1 +Cc1cc(C)c(Oc2ccc([N+](=O)[O-])c(NC3CCN(Cc4ccc(C(N)=O)cc4)CC3)c2)c(C)c1 +COCC(=O)N1CCC(n2c(C)nc3cnc4cc(F)c(-c5ccc(Oc6nccc(C)n6)cc5Cl)cc4c32)CC1 +CN1CCN(c2cc3c(cc2Nc2ccccc2)[nH]c(=O)n3CC2CCCCC2)CC1 +CCCCCCC=C1CC(CO)(COC(=O)c2ccc(OC)cc2)OC1=O +CCCCNc1ncc(C(=O)Nc2ccc(F)cc2)c(NC2CCC(O)CC2)n1 +Cc1ccc2[nH]c3c(c2c1)CN(CCCCCCCN1CCc2[nH]c4ccc(C)cc4c2C1)CC3 +CCNC(=O)C1OC(n2cnc3c(N)nc(NC(CC)CC)nc32)C(O)C1O +CCN1CCN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CC1 +COc1ccc(-c2ccc(C3CC4(C)C(CC(C)C4C(=O)C4CC4)C4CCC5=CC(=O)CCC5=C34)cc2)cn1 +COc1ccc(CNc2ccc(C(F)(F)F)c(OC3CCN(C)C3)c2)cc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2c2ccc(OC)nc2)n2c1COCC2)c1ccccc1 +O=C(c1cc(OCC(F)(F)F)c(C2CC2)cn1)N1CCCC12COC2 +N#CC1(NC(=O)C2CC(S(=O)(=O)c3ccccc3Cl)CN2C(=O)C2(c3ccc(I)cc3F)CC2)CC1 +Cc1ncccc1Oc1ccc(NC(=O)c2csc3ccccc23)cn1 +N#CC1CCCN1C(=O)C(N)CCCC(=O)N1Cc2ccccc2C1 +COc1cc2nc3c(c(N)c2cc1OC)CCC(CNC(=O)c1ccoc1)C3 +CN(Cc1ccc(-c2nccnc2NS(=O)(=O)c2ccccc2C(F)(F)F)cc1)c1cccc(F)c1 +CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)cc2OCC(F)(F)F)c1 +CC(C)(C)C(CO)NC(=O)n1c(=O)n(CCN2CCOCC2)c2ccccc21 +O=C(OC(CCCc1ccccc1)Cc1ccccc1)C1CCCCN1S(=O)(=O)Cc1ccccc1 +C=C(C)CC1CN2CCc3cc(OC)c(OC)cc3C2CC1O +O=C(NCCCCc1ccccc1)n1c(=O)oc2ccc(-c3ccc(F)cc3)cc21 +COc1ccccc1C(=O)NCC1(N2CCN(C(C)C)CC2)CCN(c2ccccc2)CC1 +CCCOCCn1c(=O)c(NCc2cnccn2)nc2cnc(-c3ccc(OC)nc3)cc21 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccco1 +COc1cc(C(=O)NC2CCN(CC3CC3)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N2CCOCC2)c1=O +CCCCNC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccc(N4CCCC4)cc3)c2C1 +CCCOc1c(OC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)CCCO +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CCN1CCS(=O)(=O)CC1 +CC(C)c1nn(C)cc1-c1nc2c(N3CCN(Cc4cccnc4)CC3)c(Br)cnc2[nH]1 +CCC(CN1CC(C)OC(C)C1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +NC1=NCC(Cc2cc(I)c(O)c(I)c2)C(N)=N1 +CN1CCCC(Oc2cccc3[nH]c(=O)c(-c4nc5ccccc5[nH]4)c(N)c23)C1 +O=C(O)CNC(=O)c1c(=O)oc(O)c2cccc(-c3ccc(F)c(F)c3)c12 +O=C(Nc1cc2c(OCCC3CCCCN3)c(-c3ccc(Cl)c(Cl)c3)c(O)nc2cc1Cl)NC1CC1 +CN1C(=O)C(=NCCc2ccc(S(N)(=O)=O)cc2)c2cc(Br)ccc21 +Cn1ccc(C2CCNCC2C(=O)N(Cc2cc(CCCC#N)cc(Cl)c2Cl)C2CC2)cc1=O +CC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3cnn(C4CCN(Cc5cccnc5)CC4)c3n2)cc1 +COc1cc(CNCc2ccccc2)ccc1NC(=O)Nc1cnc(C#N)cn1 +COc1ccc(Br)cc1C=CS(=O)(=O)Nc1ccc(F)cc1S(N)(=O)=O +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(N2CCC(c3ccc(F)cc3)CC2)C1 +C=C1C(=O)OC2C1CCC1(C)CCC(OC(=O)c3ccc(I)cc3)C(C)C21 +COc1c(OCc2ccc(F)cc2)ccnc1C[S+]([O-])c1nc2cscc2[nH]1 +CCOc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCN(C(=O)OC)CC3)s2)cc1 +CCOC1N=C(c2ccccc2Cl)c2cc(Br)ccc2NC1=O +Brc1cc(Br)c2c(c1)C(NCCCNc1nc3ncccc3[nH]1)CCN2 +COC(=O)c1sc2ccccc2c1NC(=O)CCSc1ccc(Br)cc1 +Cc1cc(COc2ccc(C3(N)CCN(C(CC(C)C)C(=O)NO)C3=O)cc2)c2ccccc2n1 +O=C(O)CN(Cc1ccc(-c2ccc(Cl)cc2Cl)cc1)S(=O)(=O)c1ccc(OC(F)F)cc1 +COc1cccc(-n2cc(COc3ccc(S(N)(=O)=O)cc3)nn2)c1 +N#Cc1ccc(-c2ccccc2Cc2nc(-c3ccc(F)cc3)c(CC(=O)O)s2)cc1 +Cc1ccc(Nc2ccc(-c3ccncc3F)nc2)c(C(=O)O)c1 +O=C(NCCC1CCN(Cc2ccccc2)CC1)c1cccnc1 +CC1CN(C(=O)C2CN(c3cnccn3)CC2c2ccc(F)cc2F)CC(C)C1(O)c1ccccc1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)N(CC(F)F)CC(F)F)c12 +CCC1CC2C(CCC3(S(=O)(=O)c4ccc(C#N)cc4)c4c(F)ccc(F)c4OCC23)NS1(=O)=O +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CC4CCOC4)ncc3Cl)C2)cc1 +Nc1ncc(-c2cn[nH]c2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12 +O=C(OCC12CCN(CC1)CC2)c1c[nH]c2cc3c(cc12)OCCO3 +CC(C(=O)Nc1cnccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1)c1ccccc1 +COc1ccc(S(=O)(=O)N2CCCC2C(=O)Nc2ccc(F)c(C)c2)cc1 +CC(C)C(NC(=O)COc1ccccc1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)F)C(C)C +O=P1(c2ccccc2)OC(COCc2ccccc2)C(OCc2ccccc2)C(OCc2ccccc2)C1O +CC(=O)Nc1ccc(-c2ccc3c(c2)CCC(C)N3C(=O)c2ccc(O)cc2O)c(C)n1 +Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-c3c(C(=O)N(C)C)sc4c(F)cc(F)cc34)cc2)cc1 +COc1ccc(C(=O)c2ccc(C(=O)c3ccc(N(CC4CC4)c4ccc(Cl)cc4)cn3)cc2C(=O)O)cc1 +CCS(=O)(=O)NCCOc1nc(N2CCOCC2)nc(NS(=O)(=O)c2ccc(C(C)C)cn2)c1Oc1ccccc1OC +Cc1nn(CCOCC(F)(F)F)c2c(Nc3ccncn3)nc(N3CCCNCC3)nc12 +O=C(Nc1ccc(F)cc1)C1(C(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)[nH]c34)c(F)c2)CC1 +NC1=NC(c2cccc(Oc3ccc(Cl)cc3)c2)N(c2cccc(Cl)c2)C(N)=N1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ncc(C)cc1F)CC2 +COCc1ccc2n1CC(N1CCN(C)CC1)c1cc(Cl)ccc1S2 +CNC(=O)N1CCC(Nc2ncc(C(=O)NO)cn2)(c2ccccc2)CC1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC3CCCC3)n1)C(C)(C)CN2 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+NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccnnc3)c2)c1 +CCCC(=C(c1ccc(O)cc1)c1ccc(OCCN)cc1)c1ccccc1 +CNC(=O)OCc1ccc(Oc2c3ccccc3nc3ccccc23)cc1 +CCNC(=O)N1CCCN(c2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2NC(=O)c2cccs2)CC1 +COc1cc(C(=O)c2cc3cc(N)cc(OC)c3s2)cc(OC)c1OC +Cc1nc(CN2C(=O)c3c(nc(N4CCCC(N)C4)n3Cc3cc(F)ccc3C#N)N3CCCN=C23)nc2ccccc12 +O=C1CCC2(OCCCc3ccccc3)C3Cc4ccc(O)c5c4C2(CCN3CC2CCC2)C1O5 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccccc2O)c1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)c2ccccc2)c1 +CCCCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(C)CC2)cc1 +CCOc1cc(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)C23C)c2ccccc2c1 +CC(C)Oc1ccc(Sc2nc(N)nc3c2ncn3CCOCP(=O)(OCC(F)(F)F)OCC(F)(F)F)cc1 +CN1C(=O)CC(c2ccccc2F)C1C(O)c1ccc(-c2ccc(F)cc2)s1 +COc1ccc2cc(Br)ccc2c1CN1C(=O)C(NC(=O)C(N)C(C)O)C2(CCOCC2)Oc2ccccc21 +NC(=O)C1(c2ccncc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +COCCc1cc(C(F)(F)F)nc2nc(N)c(C(N)=O)cc12 +CC(C)=CCc1cccc2c(C3=C(O)C(O)=CC(=O)C3=O)c[nH]c12 +Nc1nnc(-c2ccccc2Nc2cccc(C(F)(F)F)c2)o1 +CNCC(Nc1ncnc2c(C(N)=O)cc(OC)cc12)c1cccc(F)c1 +O=C(Oc1ccc(F)cc1)N1CCC(N(C(=O)c2ccc(-c3cnco3)cc2)C2CC2)CC1 +CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cn3)c2)c2cnccc21 +COc1cc(C(=O)N2CCOCC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)n2ccnc2c1C(N)=O +NC(CCCN1CCN(c2ncc(F)cn2)CC1)C1CCCCC1 +CCCC(=O)N1CCC(NC(=O)C(N)Cc2c(C)cc(O)cc2C)c2cc(Cc3ccccc3)ccc21 +Cc1ccc(N(C)C)c(C(=O)N2C3CCC2C(COc2ccccn2)C3)n1 +CC1CCCN(C(C(=O)Nc2ccc3c(c2)OCCO3)c2ccccc2)C1 +CC(C)CC(NC1CCC(n2cc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)CC1)C(=O)N(C)C +CC(C)Oc1cccc(NC(=O)c2cncc(N3CC4CNCC4C3)c2)c1 +COCCC(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +Fc1ccc(-c2noc(C3CCN(c4cnc5ccc(Cl)cc5c4)CC3)n2)c(Cl)c1 +CC(C)NC(=O)c1c[nH]c2ncc(Nc3ccc(C=C(C#N)C(=O)N4CCOCC4)cc3)nc12 +CCC(=O)N1CCC(NC(=O)NC2CC2c2ccccc2)CC1 +O=C(NCc1ccc(Cl)cc1Cl)N1CC2(CCN2S(=O)(=O)c2ccc(F)cc2)C1 +COc1nccc2c1ccc1nc3cccc(C(=O)NCCN(C)C)c3nc12 +COCCCCn1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)c2cccnc21 +CN(C)S(=O)(=O)n1c(N)nc2ccc(-c3[nH]c(-c4c(F)cccc4F)nc3-c3ccccc3)cc21 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+O=C(C#Cc1ccccc1)N1Cc2c(nc3ccccc3c2O)C1c1ccc2c(c1)OCO2 +O=C(O)CNC(=O)CNC(=O)COc1ccc2nc3n(c(=O)c2c1)CCC3 +NC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(Br)n3)CC3CC32)c2ncccc12 +CCc1nn(Cc2ccc(-c3nc4nc(OC)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O +CC12CC(N)C(C)(O1)C1C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C12 +COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3c(C)[nH]c4cc(F)ccc34)c2cc1OC +CCOC(C)Oc1cc2ncnc(Nc3ccc(C)c([N+](=O)[O-])c3)c2c2c1OCCO2 +Cc1cc(N2C(=O)c3c(c(CO)nn3C3CC3)C2c2ccc(Cl)cc2)cn(C)c1=O +Cc1ccc2c(c1)c(C#N)cn2-c1ccc(C(=O)O)c(O)c1 +CCN(CC)c1ccc(CN(C2CCCC2)S(=O)(=O)c2ccc(C)cc2)cc1 +Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c2)n(C)n1 +COc1ccc(-c2cnc(N3Cc4c(nc5ccccc5c4O)C3c3ccc4c(c3)OCO4)nc2)cc1OC +Cc1cc(-n2[nH]c3c(cnc4ccccc43)c2=O)c(Br)s1 +O=c1[nH]c2cccc(OCC3CCN(CCC4CCc5[nH]c6ccc(F)cc6c5C4)CC3)c2o1 +Nc1ccc(-c2cc3c(cc2F)c(=O)c2c(=O)[nH]sc2n3C2CC2)cc1 +COCCN(CCOC)c1nn2c(-c3ccc(OC(C)C)cc3)nnc2c2ccccc12 +CC1CCCN1CCc1cc2cc(CNc3ccc([N+](=O)[O-])cn3)ccc2o1 +O=C(O)CCN1CCCC1COc1ccc(Oc2ccc(Cl)cc2)cc1 +CC(Nc1ncnc2[nH]c(-c3ccc(C#N)cc3)cc12)c1ccccc1 +CCCCc1nn(Cc2ccccc2C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(O)CN(C(=S)CCc1nc2c(F)c(F)cc(F)c2s1)c1ccccc1 +Cn1nccc1-c1cc(Cl)ccc1Oc1ccc(S(=O)(=O)Nc2ncccn2)cc1Cl +CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)N1CC(O)C1 +CCOC(=O)c1c(C)nc2sc(C(=O)c3ccc(OC)cc3)c(N)c2c1-c1ccc(OC)cc1 +CN(C)c1ccc(-c2nnc3c(C(=O)c4ccccc4)nc4ccccc4n23)cc1 +COc1nc(C(C)(C)NC(=O)c2nnc(C)o2)nc(C(=O)NCc2ccc(F)cc2)c1OS(C)(=O)=O +CC1=NN(c2cccc(S(N)(=O)=O)c2)C(=O)C1 +COc1ncc(-c2ccc3nccc(-c4ccnnc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +CCC(CS(=O)(=O)C(C)(C)C)N1C(=O)C(C)(CC(=O)O)OC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cc1coc2c1C(=O)C(=O)c1c-2ccc2c1CCCC2(C)C +COC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4cccc(C)c4)c(F)c3)ccn2)c1 +NC(=O)c1cnc2[nH]ccc2c1NC1CCN(c2ccc(C(F)(F)F)cn2)CC1 +CC(=O)N1CCCC1C(=O)N(C1CCCCC1)C1(C(=O)NC=Cc2c[nH]c3ccccc23)CCCCC1 +COc1cc2ncc(C(N)=O)c(Nc3cc(C)ccc3F)c2cc1OC +Cc1ccc2c(C)cc(C)c(-n3c(SCC(=O)Nc4ccc(S(N)(=O)=O)cc4Cl)nnc3C(F)(F)F)c2n1 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+O=C(NC1CCOCC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +Cn1cc(-c2cnc3[nH]cc(-c4cnn(Cc5ccc(F)c(F)c5)c4)c3c2)cn1 +COC(=O)Cc1ccc(NC(=O)c2cccc(-c3cc(C(=O)Nc4ccncc4F)ccc3CN)c2)cc1 +Cc1ccc(OCCOc2c(Cl)cc(Cl)cc2Cl)c([N+](=O)[O-])n1 +CC(C)(C)n1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c(-c2ccc(F)cc2F)n1 +CCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C)cc4)cc3)[nH]c2n(CC)c1=O +CC#Cc1csc(-c2ccc3c(c2)C2(N=C(N)N(C(C)C)C2=O)C2(CCC(OC)CC2)C3)c1 +COc1cc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)ccc1OC(F)F +O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1C(F)(F)F +Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OCCO)cc2)o1 +Cc1cc(C(=O)Nc2cc(C(F)(F)F)n(C)n2)ccc1-c1nc(C2CCC3CCC(=O)N3C2)n2ccnc(N)c12 +Oc1ccc2c(c1)nc(N1CCNCC1)n2Cc1ccccc1 +COc1cc(CCC(N)(C(=O)O)C2CC2C(=O)O)cc(OC)c1 +O=C1c2cccc3c2c(nn3Cc2ccccc2)CN1C1CN2CCC1CC2 +O=C1Nc2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc2C1=O +O=C(Nc1cc(C(=O)N2CC(O)C(O)C2)nn1-c1ccccc1)c1cc(-c2ccccn2)c(F)cc1Cl +CCC1OC2(CCC3=Cc4c(cnn4-c4ccc(F)cc4)CC32C)OC1CC 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+CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CCN5CCCC5C4)cn3)nc2n1C1CCCC1 +CCCCOc1cccc(C2NC(=S)NC3=C2C(=O)c2ccccc23)c1 +COc1cc(CN(CC(C)C)C(=O)C2CCN(Cc3ccccc3)C2)cc(Cl)c1OC +COc1ccc(Oc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c(Cl)c1 +COc1ccc(C2CN(CCCc3ccc(OC)c(OC)c3)CC2CNC(=O)c2cccc(Cl)c2)cc1 +CCS(=O)(=O)N1CCC(Oc2ccc3c(c2)CCC2(CCN(C4CCC4)CC2)O3)CC1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3cccc(F)c3)CC2)nc2ccsc12 +CCCC(=O)OCCNc1cc(Sc2nc3ccccc3[nH]2)c2nonc2c1[N+](=O)[O-] +Cn1c(-c2ccco2)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O +Nc1nc(N)c2cc(CNc3ccc4ccccc4c3)cnc2n1 +CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)c2cccn2c1)C(=O)C1CC1 +CS(=O)(=O)N1CCC(C(O)c2cncnc2Nc2ccc(C#N)cc2)CC1 +CN(CCC(=O)O)C(=O)c1ccc2c(c1)CCC1C2CCC2(C)C(c3cncc(F)c3)=CCC12 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)[n+]1ccccn1 +COc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCc1ccccc1)C3c1ccc(C)cc1 +Cn1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(C)C(Oc1cc(C=C2SC(=S)N(CC(=O)O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 +CCC1CN(c2ccc(C(F)(F)F)cc2)C(=O)c2c(-c3ccnc(C)c3)cnn21 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+CC(C)(O)c1ccccc1CSC(CCC1(CC(=O)O)CC1)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1 +CCOc1ccc(CC2CN3C(=NCC3C)N2CCC2CC3CCC2C3)cc1 +COC(=O)c1ccc2c(c1)NC(=C1C(=O)Nc3c1cccc3C(F)(F)F)C2=NO +COc1ccc(N2CCN(CCCCNC(=O)C(C)(C)C)CC2)cc1 +COC(=O)c1oc2c(O)c(OC)ccc2c1C(=O)c1cc(OC)c(OC)c(OC)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CC4CCOC4)ncc3Br)C2)cc1 +CCC(CC)N(Cc1ccccc1C(F)(F)F)C1CCNCC1 +CCCCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1 +CC(C)(C)c1ccc(Sc2ccccc2N2CCNCC2)cc1 +Cc1c(Nc2nc(Cc3c(Cl)cccc3Cl)c3nc[nH]c3c2C(N)=O)ccc(N2CCNCC2)c1C +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3CC3CCCO3)ccc2[nH]1 +Cc1cncc(-c2cc3c(cn2)cnn3-c2ccc(C)c(N3CCCC(N)C3)n2)n1 +CCC(CC)N1CCN(C(=O)c2nc3c(C(N)=O)cc(F)cc3[nH]2)CC1=O +NC(=O)c1ccc2c(c1)CCOC2CCN1CCN(c2c[nH]c3cc(F)ccc23)CC1 +O=S(=O)(NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2)C1CC1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3OC(F)F)c(Cl)c2)cc1 +CC1CN(Cc2ccc(-c3ccccc3)cc2)C(=O)O1 +Cc1ccn2c(=O)c(CCN3CCc4oc5ccccc5c4C3)c(C)nc2c1 +COc1cc(Nc2nc(NC(C)c3ncc(F)cn3)nc(N3CCOCC3)c2F)n[nH]1 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+O=C1CC(c2ccccc2)(c2ccccc2)C(=O)N1CCCCN1CCN(c2nsc3ccccc23)CC1 +CCCCNc1ncc(C(=O)Nc2ccc(C(F)(F)F)cc2)c(NC2CCC(O)CC2)n1 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(CC(C)(C)O)ccc3Cl)nnc12 +Cc1c(NCC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)n[nH]c1-c1ccccc1 +CC1(COc2cc3c(cc2F)Oc2ccc(-c4cccnc4)cc2C32COC(N)=N2)COC1 +O=c1ccc(-c2ccc3c(c2)ncn3-c2ccccc2)cn1CCCN1CCCCC1 +COc1ccc(-c2c(F)c(F)cc3cc4n(c23)CCNC4=O)cc1 +OCc1cc(C(O)CNCCc2ccc(Nc3ccc4ccccc4c3)cc2)ccc1O +COC(=O)C(C)(C)Nc1nc2c(-c3cc4c([nH]3)CCNC4=O)cccc2nc1C +CNS(=O)(=O)c1ccc(NC2C3CC4CC(C3)CC2C4)c(NCc2ccncc2)c1 +CC1CN(C(=O)c2ccc(-c3cc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)s2)CC(C)N1 +OC(CCN1CCN(c2cccc3ccccc23)CC1)c1csc2ccccc12 +Cc1cc(-c2nc(-c3ccc(OC(F)F)c(C)c3)n3c2CCOC(C)C3)cc(CF)n1 +COc1cc(N)c(Cl)cc1C(O)CCC1CCN(CC2CCCCC2)CC1 +Cc1ccc(-n2nccn2)c(C(=O)N2C(C)COCC2Cc2cccc(-n3nccn3)c2)c1 +CN1CCN(Cc2cccc(NC(=O)Nc3cccc4c3C3CCCCN3C4=O)n2)CC1 +CC(C)(N)C(=O)NC(COCc1cc(Cl)cc(Cl)c1)c1nnnn1CCOC(=O)NCCCCO +CC(C)(C)OC(=O)N1CCc2c(sc(NC(=O)c3ccc(OCc4ccccc4)cc3)c2C(N)=O)C1 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+COC1CCN(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C(C)C1 +COc1ccc(N(C)c2cnc(SCc3c(F)cccc3F)n2-c2ccc(F)cc2F)cc1OC +NC(=O)c1cnc2ccc(S(=O)(=O)c3ccccc3)cc2c1NC1CCCCC1 +CN(O)C(=O)CC(CCCc1ccccc1)CP(=O)(O)O +c1ccc2nc(N3CC(Oc4nccnc4N4CCC5(CC4)COC5)C3)ccc2c1 +COc1ccnc(Oc2ccc(-c3c(C)n[nH]c(=O)c3C)c(C)c2)c1C(F)(F)F +CC(=O)c1cccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +CCCCOc1ccc(C(=O)NC(C)C(=O)NC2CCc3ccccc3C2)cc1 +COC(=O)C(C)Nc1c(C(=O)NCc2ccc(F)cc2F)c(=O)n(O)c2ncccc12 +CN1CCN(c2ccc(-c3cc4ncn(C)c(=O)c4c(N4CCC(N)C4)n3)cc2)CC1 +Cc1nc(NC(C)c2ccc(C)c(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccccc5)CC4)cc3)[nH]c2c1=O +O=C(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc(N=Nc2ccccc2)cc1 +Nc1nc(-c2ccccc2Cl)c2c(n1)N(c1c(Cl)cccc1Cl)C(=O)NC2 +COc1cc(C2c3cc4c(cc3C(CCN(C)CCN(C)C)C3COC(=O)C23)OCO4)cc(OC)c1O +CC(C)N(Cc1ccccn1)C(=O)C(C)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O +O=C(NCCc1ccc(OCCN2CCCC2)c(Br)c1)c1cccc(C(F)(F)F)c1 +CNc1nccc(-c2cc(C(N)=O)c(-c3cc(Cl)ccc3C)[nH]2)n1 +O=S(=O)(Nc1nccs1)c1ccc2c(-c3ccc(C(F)(F)F)cc3Cl)ncnc2c1 +CNCC(O)C(c1cccc(F)c1)n1ccc2cccc(Br)c21 +CC(NC(=O)CC#N)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 +CCC(O)(CC)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)C(C)(C)N)CC1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CN3CCNCC3)c2)cc1 +Cn1c(C(=O)N2CCCNCC2)cc2[nH]c(=O)c3ccccc3c21 +CCOc1cc(-c2nncn2C)ccc1Nc1ncc2cc(C)nc(NCC(C)(C)C)c2n1 +COc1cccc2oc(=O)nc(NCC(C)(C)c3ccccc3)c12 +COc1c(C)c(C)c([N+](=O)[O-])c(N)c1CC=C(C)CCC(=O)O +COc1ccc(CC(C(=NOCCCCC(=O)O)C2CCCCC2)n2ccnc2)cc1 +Cn1c(-c2ccccc2C(F)(F)F)nnc1-c1cccc(F)c1F +Cc1cccc(CNC(=O)NC(CC(C)C)C(=O)NO)c1 +Cc1cccc(-c2nnc3n2CCN(C(=O)c2ccc(F)cc2)C3C)n1 +CC(CC(C)(C)C)NC(=O)C1CC2CC2N1C(=O)Cn1nc(C(N)=O)c2ccccc21 +Cc1cc(COc2ccc(S(=O)(=O)N3CCN(C(=O)C4CC4)C(C(=O)NO)C3)cc2)c2c(n1)CCCC2 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(C(C)CNCc3ccccc3C)c2=O)c1 +CCOc1cc(C)nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(C(=O)NC)cc4)c3Cl)cccc12 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+CC(=O)N(C1=C(N2CCCC2)C(=O)c2ccccc2C1=O)c1ccc(F)cc1 +CC(C)(c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1)c1cccs1 +O=C1Nc2ccc(C(=O)c3ccccc3)cc2C1=Cc1cc(Br)c(O)c(Br)c1 +CCCCCCCN(CCCCCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)[nH]1)C(=O)Nc1ccc(F)cc1F +Cc1cc(CC(=O)Nc2cc(C(=O)c3cn(C(C)C)c4ccncc34)ccn2)[nH]n1 +CCN(C(=O)c1ccccc1CC(O)CCc1ccccc1C(=O)N(CCO)C1(CC)CCCC1)C(C)(C)c1ccccc1 +C[N+]1(C)CCC(OC(=O)C2(c3ccccc3)CCCCCC2)CC1 +C[n+]1c2ccccc2c(Nc2cccnc2)c2[nH]c3ccccc3c21 +CC(=O)CCCCCC(NS(=O)(=O)c1ccc([N+](=O)[O-])c(F)c1)c1ncc(-c2ccccc2)[nH]1 +CCc1[nH]c2nc(Sc3cncnc3)nc(N3CCC(N)C3)c2c1Cl +CCCN(Cc1sc(N(C)c2c(C)cc(C)cc2Cl)nc1C(F)(F)F)CC1CC1 +CN1C2CCC1CC(Oc1ccc3c(c1)C(=O)c1cc(OC4CC5CCC(C4)N5C)ccc1-3)C2 +Cc1cnc(Nc2cnn(C)c2)nc1NC1CN(C(=O)CC#N)CC12CCCC2 +CCOC(=O)c1cc2c(N)c3c(nc2nc1C)CCCCC3 +Cc1cc2ccccc2c(Cn2c(=O)c3c(nc(N4CCCC(N)C4)n3Cc3ccccc3Br)n(C)c2=O)n1 +c1ccc(-c2n[nH]c3cnc(-c4ccoc4)cc23)cc1 +C=C(C=CC=CC(=O)O)c1cc(C(C)(C)C)cc2c1CCC2(C)C +CCc1cccc2c1NC(=O)C2(c1ccc(O)cc1)c1ccc(O)cc1 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+CC1CCC2C(C)C(c3cccn3Cc3ccco3)OC3OC4(C)CCC1C32OO4 +c1ccc(CCOCCOc2ccc(C3CCNCC3OCc3ccc4ccccc4c3)cc2)cc1 +O=C1CC(c2ccccc2)CC(=O)N1CCCCN1CCN(c2ccccc2Cl)CC1 +CC1NC(=O)C(C(C)C)NC(=O)CC(C=CCCS)OC(=O)CC(O)C(C(C)C)NC1=O +CCC(=O)NC(C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(O)C2)cc1 +COC(=O)C1=C(c2ccc3ccccc3c2)CC2CCC1C2 +CC(=O)NC(C)c1ccc(OC2CCN(c3cc(C(F)(F)F)ccn3)C2)cc1 +Cc1cccc2cc(Cn3nc(I)c4c(N)ncnc43)n(-c3ccccc3OCCN3CCOCC3)c(=O)c12 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccnc4ccccc34)cc12 +COc1ccc(-c2ccc3nnc(C(C)c4ccc5ncccc5c4)n3n2)cc1F +O=C(Nc1ccc(S(=O)(=O)N2CCCCC2c2cccnc2)cc1)c1c(F)cccc1F +Cn1cc(-c2cnc3[nH]cc(-c4cnn(Cc5cccc(C(F)(F)F)c5)c4)c3c2)cn1 +OC(c1ccccc1)C1CCN(CCCCc2ccccc2)CC1 +O=C(CCl)NNC(=O)CSc1nnc(Cc2csc(NC(=O)c3ccccc3)n2)n1NC(=O)c1ccc(Cl)cc1 +CC(O)C1CCN(c2cc(-c3n[nH]c4ccc(-c5cnn(C)c5)cc34)ncn2)C1 +CC1(C)CC=C(c2cc(CN3CCN(CCO)CC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +Cc1cccc(Cc2nc(N)nc(N3CCN(C)CC3)n2)c1 +COc1ccc2nccc(CCC3CCC(NCc4ccc5c(n4)NC(=O)CS5)CO3)c2n1 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+O=C(CCSc1nc2c(c(=O)[nH]1)CCCC2)NC1CCC(c2nnc(-c3ccccc3)o2)CC1 +COc1cccc(-c2n[nH]c(Cc3cccc([N+](=O)[O-])c3)n2)c1 +Cc1cccc(-c2csc(N3CC4CC4(C(=O)O)C3)n2)c1OCc1ccc2c(c1C)CCN(C1CCOCC1)C2 +O=C(NCC(c1cccnc1)N1CCN(c2ccccc2F)CC1)OCc1ccccc1 +COc1c(C=Cc2ccc(NS(C)(=O)=O)cc2)cc(-c2cc(F)c[nH]c2=O)cc1C1(Cl)CC1 +CC(Nc1ncnc2oc(-c3ccc(NCCN4CCCCC4)cc3)cc12)c1ccccc1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1C1CCCC1 +O=C(NC1c2ccccc2CC1O)C(CC(O)C(OCc1ccccc1)C(=O)NC1c2ccccc2CC1O)OCc1ccccc1 +O=C(NCc1ccc(Cl)cc1)c1cn2c(CCN(CCO)CCO)cc3cc(CN4CCOCC4)cc(c1=O)c32 +Cc1cccc(S(=O)(=O)c2n[nH]c3ccc(N4CCN(C)CC4)cc23)c1 +OCc1cc(C(O)CNCCc2ccc(NCC(O)c3ccc(O)c(CO)c3)cc2)ccc1O +CN(C(=O)Nc1ccn(-c2ccccc2F)n1)C1CCC2(CC1)OC(=O)c1ccccc12 +COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OCCCN(C)C +COc1ccc(CNc2ccc3c4c2OC2C(O)C=CC5C(C3)N(C)CCC452)cc1 +N#CCOc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F +CC1(c2cc(NC(=O)c3ccc(C(F)(F)F)cn3)ccc2F)CS(=O)(=O)C2(CCCC2)C(=N)N1 +OC1CNCc2nc(-c3ccc(N4CCCC4)cc3)sc21 +NC(CCSCC1OC(n2cnc3c(NCCCc4ccccc4)ncnc32)C(O)C1O)C(=O)O +CCc1cc2c(=O)n(CC3(O)CCOCC3)c(=O)n(Cc3ccc(-c4ccccc4-c4nc(=O)o[nH]4)cc3)c2s1 +CCOc1cc(=O)n(C)cc1-c1cc(NCc2cnco2)ccc1Oc1ccc(F)cc1F +O=S(=O)(c1ccc(-c2cnc(C3CC3)o2)cc1Cl)N1CCc2ccccc21 +COCc1cc(OC)c(-c2c(C)sc3c(N(CC4CCOCC4)CC4CC4)c(C)nn23)c(OC)c1 +Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCNC1 +CCn1nnnc1C1OC(n2cnc3c(N)nc(NC(CO)Cc4ccccc4)nc32)C(O)C1O +CCCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1ccc([N+](=O)[O-])cc1 +CC1CN2c3c(cc4c(-c5ccncn5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2CC(=O)N2CCCCC2)cc1 +CC(NC(=O)Nc1cccc2ccc(O)cc12)c1ccc(C(F)(F)F)cc1 +CCCC(O)C(CNCC(C)C)NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 +COc1cccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(=O)O)C3=O)cc2)c1 +Cc1cc(O)cc2cc3c(c(O)c12)C(=O)CCC3O +CCCCN1C(=O)N(Cc2cccc(C(=O)Nc3ncc[nH]3)c2)C(Cc2ccccc2)C(O)C(O)C1Cc1ccccc1 +Clc1ccc(-c2n[nH]c(N3CCc4ccccc4C3)c2-c2ccncc2)cc1 +CC(NC(=O)C(O)C(O)C(=O)N1CCCCC1c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1 +O=C1NC(Cc2ccccc2)C(=O)N1CC(CCN1CCC(c2ccccc2)CC1)c1cccc(Cl)c1 +CC(=O)N1CCC(Nc2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 +CC(c1nnc2c(F)cc(-c3cnn(C)c3)cn12)n1ccc2ncccc2c1=O +CCn1c(CCc2ccccc2Cl)nc(N2CCNCC2)cc1=O +CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc2nonc2c1)C(=O)O +CN(C)CCNC(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +O=C(NC(CCO)c1ccc(F)cc1)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +CC(=O)Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1 +COCCNC(=O)c1c(NC(=O)c2ccccc2Cl)sc2c1CCC(F)(F)C2 +O=C(Nc1sc(N2CCN(CCc3ccccc3)CC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +CCn1c2ccccc2c2cc(NS(=O)(=O)c3cc(OC)ccc3OC)ccc21 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4ccc(Br)cc4)nc31)C(O)C2O +CC(C)c1nc2c(c(Nc3ccc(C(F)(F)F)nc3)n1)CCN(c1ncccc1S(C)(=O)=O)CC2 +COc1ccnc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)c1 +O=C(Nc1cccc2c1C(=O)c1c(-c3ccc(C(=O)N4CCCCC4)s3)n[nH]c1-2)NN1CCOCC1 +COc1ccc2c(c1)c(CC(=O)NOCc1ccc([N+](=O)[O-])cc1)c(C)n2C(=O)c1ccc(Cl)cc1 +Cc1n[nH]c(-c2cn3c(n2)-c2ccc(-c4cnn(CCO)c4)cc2OCC3)n1 +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)NC(C)C)c1ccc2occc2c1 +CNC(=O)C(Cc1c[nH]cn1)NC(=O)CN(CCCc1ccccc1)CC(=O)O +COc1ccccc1-c1noc(-c2ccc(-c3ccccc3C)c(C(F)(F)F)c2)n1 +NC(=O)CNC(=O)N1CCC(CC(=O)N2CCC(C3c4ncc(Br)cc4CCc4cc(Cl)cc(Br)c43)CC2)CC1 +O=C(Cn1cnc2cccc(C(F)(F)F)c2c1=O)C1NCCC1O +COc1cc(C2OCCc3nc(SCc4c(F)cccc4Cl)n(-c4ccc(F)cc4)c32)ccc1F +COc1ccccc1NC(=O)N(Cc1ccccc1)C(C)c1nc2ccccc2c(=O)n1-c1cc(C)ccc1OC +CN(C)C(=O)CC1(NC(=O)c2cc(OCC(F)(F)F)c(Cl)cn2)COC1 +COc1cccc(OC)c1-c1ccc(CC(Nc2cccc(S(=O)(=O)N3CCCC3)c2)C(=O)O)cc1 +COc1ccc(NC(=NC(=O)c2ccc(N(C)C)cc2)NC2CCCCN(CC(=O)N3CCCC3)C2=O)cc1 +N#Cc1cccc(N2CCN(CCN3CCC(C(F)(F)F)CC3)C2=O)c1 +O=C(C1CC(n2cc(-c3ccc(F)c(F)c3)nn2)CN1C(=O)CCCc1ccccc1)N1CCCC1 +CCCNc1nc(N(CCO)CCO)nc2c(NCCC)nc(N(CCO)CCO)nc12 +O=C(NC(CO)c1ccc(F)c(Cl)c1)N1CCc2cnc(NC3CCOCC3)nc2C1 +NCCCN(CCCN)C(=O)COc1ccc2sc(CNc3nncc(-c4c(Cl)cccc4Cl)n3)nc2c1 +CC(C)CC(CC(=O)NO)C(=O)NC(CC(C)C)C(=O)NC(C)C=O +CCOC(=O)CCc1ccc(-c2ccc(OC)cc2)n1-c1ccc(C(N)=O)cc1 +c1ccc(-c2cc(NCc3ccco3)nc(-c3ccccn3)n2)nc1 +COc1ccc(Oc2cc(C)c(-c3csc(NC(=O)c4ccncc4)n3)c(C)c2)cc1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc(N4CCN(C)CC4)cc3)nc12 +CN(CCO)C(=O)c1ccc(C(=C2CCN(Cc3cscn3)CC2)c2cccc3cccnc23)cc1 +CC(CO)NC(=O)CCCC=CCC=CCC=CCC=CCCCCc1cccc(Br)c1 +COc1cc(CNCCc2ccccc2)cc(Br)c1OC1CCCC1 +CN1C(=O)N(CC(COc2ccc(-c3ccc(C#N)cc3)cc2)N(O)C=O)C(=O)C1(C)C +Cc1cc(-c2cc3c(NCc4cccnc4N(C)S(C)(=O)=O)c(C#N)cnc3[nH]2)ccn1 +Nc1ccccc1NC(=O)c1ccc2nc(N3CCNCC3)ccc2c1 +COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 +CCc1nccc(-c2ccc(C(=O)N3CCN(CC)C(C)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +COc1ccc(NC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccccc3)CCCCC2)cc1 +NC1(c2ccc(-c3nc4c5cccc(-c6ccc(CO)cc6)c5nn4cc3-c3ccccc3)cc2)CCC1 +CCN(CC)C(=O)c1ccc(C(=O)NC)c(NC(=O)c2nc(C(C)(C)C)ncc2Nc2cncnc2)c1 +Nc1ncc(Cc2ccc([N+](=O)[O-])cc2)c(N)n1 +COC(=O)C=CCCC1C(c2ccccc2)CC2CCC1N2C +O=C(COc1cccc(NC2CCOCC2)c1)NCC(O)CN1CCc2ccccc2C1 +CN(C)C(=O)Nc1cc(Oc2cc(F)c(NC(=O)N3CCN(C4CCOCC4)C3=O)cc2Cl)ccn1 +C=CCOc1ccc(CCCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 +COc1ccc(-c2cc3c(C)nc(N)nc3n(CC(C)(C)O)c2=O)cn1 +CC(C)(C)c1cc(Cl)ccc1OCC1CN(C(=O)C(=O)O)C1 +CN1CCC(c2cc3c(-c4cncc(NCc5cccnc5)n4)ccnc3[nH]2)CC1 +COc1ccc(NS(=O)(=O)c2ccc(N=Nc3cc(C)c(O)c(C)c3)cc2)nc1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(NCCN2CCN(C)CC2)nc1 +Oc1ccc2c(c1)C13CCN(CCc4ccccc4)C(C2)C1Cc1cc2ccccc2nc1C3 +O=C(NC(CO)c1ccc(F)cc1)c1ccc(-c2c[nH]c3ncccc23)s1 +COc1ccc(C(C)(NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)Nc2cccc(Oc3ccccc3)c2)cc1 +Cc1cccc(NC(=O)Nc2ccc(-c3c(C)nc4ccnn4c3N)cc2)c1 +Cn1nc(C(F)(F)F)cc1C(=O)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +CCc1cccc(N(C)C(=N)Nc2cc(SC)cc(CC)c2Br)c1 +CC(C)(C)n1nc(-c2ccc3ccccc3n2)c(C(N)=O)c1N +COCCOc1cc2ncnc(NC3=C(Cl)C(=O)C=C(OC)C3=O)c2cc1OC +COc1cc(C(F)(F)F)cc(S(=O)(=O)c2cccc(N)c2C#N)c1 +Cc1nc2cccc(C(=O)O)c2n1Cc1ccc(-n2cccc2C(=O)O)cc1 +CC1CCCN1c1cccc(Nc2cc(-c3cccc(OCCN4CCOCC4)c3)nn3ccnc23)n1 +NCC1CCCN(c2ccncc2-c2cc3c(-c4ccccc4F)n[nH]c3cn2)C1 +O=C(COc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 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+O=C(Cn1c(=O)ccc2cc(F)c(F)cc21)Nc1scc(Br)c1-c1ncn[nH]1 +Cc1nc2cnc3ccc(C#CCNC(=O)c4cccn(Cc5ccccc5)c4=O)cc3c2n1C(C)C +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cccnc1 +CNCC(O)Cn1c2ccc(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +O=C(CCc1ccc(Nc2nccc(Nc3cc(C4CC4)n[nH]3)n2)cc1)NCCCN1CCCCC1 +CC(C)(C)CC(=O)Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1 +CCOCCn1cc(C(=O)NCc2ccc(Cl)cc2Cl)ccc1=O +O=C(O)CCCN1CC(C(=O)O)Oc2c(CCc3ccc(OCCCCc4ccccc4)cc3)cccc21 +Cc1ccccc1C(=O)NCC1(c2ccccc2)CCN(C)CC1 +NCCCCC(NC(=O)OCc1ccccc1)C(=O)c1noc(Cc2ccc(C(=O)NCCc3cccs3)cc2)n1 +O=C(CCl)OCCn1c(=O)oc2cc3ncnc(Nc4ccc(N5CCOCC5)c(Cl)c4)c3cc21 +Nc1nnc(-c2ccc3[nH]cc(-c4nccc(N5CCCC(O)C5)n4)c3c2)o1 +NC(=S)Nc1cccc(OCCCCCN2CCN(c3cccc4ccccc34)C2=O)c1 +Cn1c(=O)c(Oc2cccc(F)c2)cc2cnc(NC3CCOCC3)nc21 +C=CCCC(CC1OC(=O)C1CCCCCC)OC(=O)C(Cc1ccccc1)NC=O +O=C(O)CCCCC(=O)N1CC(C(=O)O)Oc2c(NC(=O)c3ccc(OCCCCc4ccccc4)cc3)cccc21 +Cn1ncc(NC(=O)c2nc(-c3ccnc(F)c3)sc2N)c1N1CCCC(N)CC1 +Oc1ccc(C2=NCCN2)cc1-c1cc2ccc(C3=NCCN3)cc2o1 +C1=C(c2ccccn2)CN(c2nnc(N3CCC(N4CCCCC4)CC3)s2)CC1 +CCC1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(F)c(F)cc3nc2-1 +Oc1ccc(C2Sc3cc(O)ccc3OC2c2ccc(N3CCCNCC3)cc2)cc1 +O=C(NCC1CCOCC1)c1cnc(Nc2cc(Cl)cc(Cl)c2)cc1C1CC1 +CCN(C(CC(C)C)C(N)=O)S(=O)(=O)c1ccc(Cl)cc1 +CCCOc1cc(Cc2c(N)nc(N)nc2CC)ccc1OCc1cc(OC)c(OC)c(OC)c1 +Cc1cc(Nc2nc(Cl)cn(C(C)C3CC3)c2=O)c(C)nc1OC(F)F +CCNC(=O)c1cc2c(-c3cc(OCCN(CC)CC)c(Cl)cc3Cl)nc(N)nc2s1 +COc1ccc2cc1COCC=CCOCc1cc(ccc1OCCN1CCCC1)Nc1nccc-2n1 +COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN1CC[S+]([O-])CC1 +CCOc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c[nH]c2c1 +COC(=O)c1ccc2cc(OC(=O)c3ccc(NC(=N)N)cc3)ccc2c1 +CCN(CC)C(=O)C1CCCN1C(=O)NCc1ccc(C(=O)N2CCCCc3ccccc32)cc1C +COc1cc(C(F)F)ccc1-c1cccn2nc(Nc3ccc(C4CCNCC4)cc3)nc12 +COCC1CCCN1CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +COc1c(-c2ccc3cc(NS(C)(=O)=O)ccc3c2)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C +O=C(c1ccccc1C(F)(F)F)N(CC1CCC1)C1CCNC1 +O=C(NCC(O)C(F)(F)F)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 +FC(F)(Cl)Oc1ccc(Nc2nnc(-c3cccnc3CCc3ccncc3)o2)cc1 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+CCc1ncccc1Oc1cc(CCCC(C)(C)O)cnc1NC(=O)NC +COc1cc(OC)cc(N(CCNC(=O)C2CCCN(C)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCS(=O)(=O)CC2)CC1 +CC(C)Oc1cccc(-c2c[nH]c3ccc(-c4nnc(N)o4)cc23)n1 +CC1(O)CCC2C(C(CCO)CCC2(C)C#N)C1C#N +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)c4cnsc4)nc23)N1 +CCOCCOC1CCN(S(=O)(=O)CC2CCC(N(C)c3ncnc4[nH]ccc34)CC2)C1 +CNC1CCN(c2cc(NCc3ccccc3)nc(N)n2)C1 +COCCN(Cc1csc(C(=O)Nc2c(OC)cc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c1Cl)C1=NCCO1 +COc1ccccc1C(c1ccccc1OC)N1CCN(CCCCNC(=O)C=Cc2ccccc2)CC1 +CCCCN(NC(=O)C(CCC)N1CCC(CCC)(NCCCC2CCCCC2)C1=O)C(=O)OCC +NC(CC(=O)N1CCCC1COc1ccnc(C(F)(F)F)n1)Cc1cc(F)c(F)cc1F +CN(C)CCc1c(-c2ccccc2)[nH]c2ccncc12 +O=S(=O)(c1ccccc1)c1c(OCCCc2ccc(O)cc2)no[n+]1[O-] +CN(CCC#N)c1cnc(C(=O)NCC(C)(C)c2ccccc2)cn1 +CC(C)(C)c1ccc(CN2CCN(C(=O)C=Cc3ccc(Br)cc3)CC2)cc1 +CCOc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc(N)c1N=O +COc1ccc(-c2cnc3cc(OC)c(OC)cc3c2)cc1 +Cn1c(C(=O)N2CCn3cc(C(=O)NO)cc3C2)cc(Cl)c1Cl +O=C1N(Cc2ccnc(Br)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)Nc2nc(CC(=O)O)cs2)n1 +CN(CCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12)CCN1CCNC1=O +CC1(C)CC=C(c2ccc(C#N)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 +COc1ccc(Nc2cc(Nc3cccc(OC(F)F)c3)nc(NC3CCCCC3)n2)cc1 +COc1ccccc1CN(C)CC1CC1c1cc(F)ccc1OC +COc1ccc(CC(O)CC(Cc2ccccc2)C(=O)NC2c3ccccc3CC2O)c(OC)c1 +Oc1ccc(-c2cncc(-c3ccc(O)cc3)c2)cc1 +CC(C)C(Sc1nc(S)c2cnn(-c3ccccc3)c2n1)C(N)=O +Cc1ccc2[nH]c3c(NCCN(C(C)C)C(C)C)ncnc3c2c1 +Cc1nn(-c2ccc3onc(N)c3c2)c2c(=O)n(-c3ccc(-c4ccccc4CNC(C)C)cc3)cnc12 +Cc1n[nH]c(C)c1CN1CCN(c2cccc3[nH]c(-c4ccc(C(C)(C)C)cc4)nc23)CC1 +COCCc1ccc(Cl)c(CN(C(=O)C2CNCCC2c2ccc(N3CCC(Oc4c(Cl)cc(C)cc4Cl)C3)nc2)C2CC2)c1 +CN(Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CCc1ccccn1)c1ccccc1 +Cc1cc(C#N)cc(C)c1Nc1nc(Nc2ccc(C#N)cc2)ncc1C#N +CCOC(=O)C1(Cc2ccccc2)c2c(cnc3c(-c4ccc(C(F)(F)F)cc4)cnn23)CN1C +CCNc1nc(OCCc2c[nH]c3ccccc23)nc2c1ncn2C1OC(CO)C(O)C1O +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCCC(N(CCO)CCO)CC1 +CC(c1c[nH]c2ncccc12)c1nnc2ccc(-c3cnn(C)c3)nn12 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+CN(CC1CCCO1)C(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +Cc1ccc(C(=O)Nc2cc(OCCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(NCC3CCOC3)nc12 +NS(=O)(=O)c1ccc(NC(=S)NN=C2C(=O)Nc3ccc([N+](=O)[O-])cc32)cc1 +CN1CCc2nc(C(=O)Nc3ccncc3CNC(=O)c3ccc(Cl)s3)sc2C1 +CCc1oc2ccc(OC)cc2c1C(=O)c1cc(Br)c(O)c(Br)c1 +COc1cccc(CNCCCNc2ccnc3cc(Cc4ccc(C#N)cc4)ccc23)c1O +CCC(c1ccccc1)n1cc(NC(=O)c2n[nH]c3ccccc23)cn1 +COc1n[nH]c2cc(NC(=O)NC3CN(C)CC3c3ccccc3C)ncc12 +COc1ccccc1-c1nnc(SCCCN2CCc3ccc(-c4cc(C)on4)cc3CC2)n1C +O=C1CCC2=C(C3Oc4c(O)ccc5c4C34CCN(CC3CC3)C(C5)C4(O)C2)N1CC1CCCCC1 +CC(C)(C)c1ccc(CNC(=O)C(C)(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(-c2cccc(C(F)(F)F)c2)cc1F +Cc1cc(C)cc(-c2[nH]c3ccc(C(=O)N4CCCCC4)cc3c2CCNCCCCc2ccc(NS(C)(=O)=O)cc2)c1 +CNCCC(c1ccccc1)n1c(=O)n(C2CCCCC2)c2ccccc21 +O=C(O)C1CCCC(NC(=O)C2(CS)CCCCC2)C1 +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CCC(C(O)C(F)(F)F)C1 +[H]C1([H])OC(C)(C)C(=O)N(c2cc(-c3cc(Cl)c4c(N)ncnn34)ccc2C#N)C1([H])[H] +CC(NC(=O)c1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1)C(=O)O +CCCc1cncnc1-c1ccc2c(c1)CCC(C)N2C(=O)c1ccc(O)cc1O +CN(C(=O)C(F)(F)F)C(C#CCN1CCCC1)c1ccccc1 +O=C1N=C(NC23CC4CC(CC2C4)C3)SC12CCCC2 +NS(=O)(=O)c1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)c(I)c1 +COCCOCc1ccc2cc(CCn3ncc4c3nc(N)n3nc(-c5ccco5)nc43)ccc2n1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCCN5CCCCC5)s4)nc23)N1 +CC1(C)CCCN(c2ncnc3[nH]cc(-c4cccc(C#N)c4)c23)C1 +Nc1nc(NN=Cc2ccc(CCC(=O)O)cc2)nc2c1ncn2C1OC(CO)C(O)C1O +O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)C1CCC1 +O=C(NC1CSSCC(C(=O)O)NC(=O)C2CCCN2C(=O)C(CO)NC1=O)c1cccc2ccccc12 +CCc1cc(-c2ccccc2)cc(CC)[n+]1CC(=O)OCc1ccc(S(N)(=O)=O)cc1 +COc1cccc(-c2cc(F)c(Nc3ncccc3C(=O)O)c(F)c2)c1F +CN1CCN(c2ccc(C(=O)NC3CCC(CCN4CCC(c5cccc6c5CCO6)CC4)CC3)cc2)CC1 +Cc1ncc(Cl)cc1C(=O)NC1CCC(CN2C(=O)C(C)(C)c3ccccc32)CC1 +O=C(O)Cc1ccc2oc(-c3ccc(NC(=O)C=Cc4ccc(F)c(Cl)c4)c(F)c3)nc2c1 +NC1CCN(C(=O)C2CCCCN2S(=O)(=O)c2ccc(-c3ccco3)cc2)C1 +O=C(c1cc(=O)c2cc(O)ccc2[nH]1)N1CCC(Cc2ccc(F)cc2)CC1 +CC(Nc1c(Nc2ccncc2)c(=O)c1=O)C1CCCCC1 +CC1(CNCc2ccc(-c3ccccc3S(=O)(=O)N3CCCC3)cc2)COC1 +CC(C)(CO)CNCc1ccc(Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)nc1 +N#Cc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cc1 +COc1cccc(C=NNc2nc(N)c3ncn(C4OC(CO)C(O)C4O)c3n2)c1 +O=C(O)C=Cc1ccc(Oc2c(C(=O)c3ccccc3C(F)(F)F)sc3cc(O)ccc23)cc1 +O=C(NC(=S)Nc1sc2c(c1C(=O)O)CC1(CCCC1)OC2)c1ccccc1 +CCOCCOc1ccn2ncc(C(=O)NCCCN3CCN(c4ccccc4OC)CC3)c2c1 +COc1cc2nc(N(C)CCCCCCN(C)C(=O)c3ccc(CN4CCSC4)cc3)nc(N)c2cc1OC +COc1ccc(Nc2ccc(Oc3ncccc3C3CCN(C(C)=O)CC3)cc2)nc1 +Cc1nc2cccc(-c3cc4c([nH]3)CCN(CO)C4=O)c2nc1NC(C)(C)C +O=C(O)Cc1cn(CC(O)CN2CCCCC2)c2ccccc12 +CS(C)(=O)=NC(=O)c1cnc(N)c(C#Cc2cccc(NC(=O)c3ccc(Cl)cc3)c2)c1 +COc1c(C(=O)NC2CCN(C3C4CCCC3CCC4)CC2)cc(Br)c2ccccc12 +Cc1c(C#N)c(-c2ccc(C#N)cc2)c(C)n1Cc1ccccc1 +CCOC(=O)c1sc2c(OC)c(C)c(C)c(C)c2c1Nc1cc(OC)c(OC)c(OC)c1 +CCC(NC(=O)c1ccc(Sc2ccc(N)cc2)c(Nc2ncnc3nc(C(C)C)ccc23)c1)c1ccccc1 +CC(=O)c1cc(NC(=O)NC2CCCCC2CN2CCCC(Cc3ccc(F)cc3)C2)cc(C(C)=O)c1 +N#Cc1c(COc2ccc3c(c2)C2CN(C(=O)C4CCCCC4)CC(=O)N2CC3)no[n+]1[O-] +Cc1ccccc1COc1cc(-n2cnc3ccccc32)sc1C(N)=O +CCCN(CCC)CCc1ccc(OCCc2ccccc2)c(O)c1 +CC(C)CCN(C)C(=O)c1c(F)cccc1OCC(=O)NC(CO)Cc1ccccc1 +O=C1NCN(c2ccccc2)C12CCN(C1(c3ccccc3)CCCCC1)CC2 +COc1ccc(-c2cc3cc(C)ccc3c(N)n2)cc1OC +CNC(=O)OC(C)C=CC(=O)NC1CCC(CC=C(C)C=CC2CC3(CO3)CC(C)(C)O2)CC1 +COc1cccc2c1C(NCC(C)(C)c1ccccc1)=NC2=O +CCc1c2c(n(C)c1C)CCCC2=NOC(=O)Nc1ccc(C(C)=O)cc1 +CNc1cc(N2CCNCC2)ccc1S(=O)(=O)c1ccccc1 +CC(C)CNC(=O)c1ccc(-c2ccc(-c3occc3CO)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +CCOC(=O)c1cc(=O)c2cc(F)cc(NC(=O)c3ccc(OC)cc3)c2o1 +Oc1cccc(-c2cc(N3CCOCC3)nc(NCCc3cccnc3)n2)c1 +CCS(=O)(=O)c1ccc(OC2CCN(C)CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +CC1(C)C(C(=O)N=C(N)N)C1c1cc(Cl)cc(Cl)c1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cncc(NS(=O)(=O)C(C)C)c3)NC(=O)NC1=O)C2 +CC1CN(CCOc2ccc(C3Oc4ccc(O)cc4SC3c3ccc(O)cc3)cc2)CC1C +N#CC1CSCN1C(=O)CN(N)C1CCN(CC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 +CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Nc3ncnc4c(N)ncnc34)c2)c1 +COc1cc(OC)c2c(C)[n+](-c3ccc(C(C)C)cc3)c(C)cc2c1 +C#Cc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1 +O=C(NCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)c1cnc(Cl)s1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(NC3CN4CCC3CC4)c2c1=O +COn1c(-c2ccc(C)cc2)cc2cc3c(cc21)C(=O)NC3=O +CCOCCn1c(=O)nc(N2CCN(CCO)CC2)c2nnc(-c3ccc(OC)nc3)cc21 +CC1COc2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc2N1C(=O)Nc1ccccc1 +COC(=O)c1[nH]c(C(C)(C)C)cc1NC(=O)Nc1ccccc1Cl +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cc(-c2ccccn2)ccc1Cl +Cn1cnc2cc(-c3ccc(C(C)(C)O)nc3)nc(Nc3ccccn3)c2c1=O +CCCOc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1-c1ccccn1 +Cc1ccc(S(=O)(=O)n2ccc(NC(=O)c3ccccn3)c2)cc1C +COC(=O)c1cccc(CN2C(=O)C3(N=C2N)c2cc(Br)ccc2CC32CCC(OC)CC2)c1 +CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(-c2ccc(N3CCN(C(C)C)CC3)nc2)cc2c1cnn2C(C)C +CCCCCCCN(CCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)C(=O)Nc1ccc(F)cc1F +COc1c(C(=O)NC2CCN(C3CCCCC3)CC2)cc(Br)c2ccccc12 +CCS(=O)(=O)c1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2CN2CCOCC2=O)cc1 +O=C(Nc1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(Cl)ccn1 +CNc1ccc(Cl)cc1C(=O)NC1CCN(Cc2ccc3c(c2)OCO3)CC1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCC(NCC2CCCCC2)CC1 +Cc1cccc(S(=O)(=O)N(C)C(CNC(=O)CC2CC(c3ccc(C(=N)N)cc3)=NO2)C(=O)O)c1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2OCC2(F)COC2)c2cc[nH]c2c1=O +CC=C1C2C=C(C)CC1(N)CC(NCCCCCCCNc1c3c(nc4ccccc14)CCCC3)C2(C)C +O=C(C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1)N1CCn2c1nc1ccccc12 +N#Cc1ccc(Oc2ccc(-n3cc(C(O)(C(N)=O)C(F)(F)F)c4ccccc43)cc2)cc1C(F)(F)F +C=CCN1CC(C)N(C(c2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)CC1C +CN(C)CCC1CCN(c2cc(C#N)c(C#N)cc2[N+](=O)[O-])CC1 +COc1ccc2c(c1)N(CCN1CCC(NCc3ccc4c(n3)NC(=O)CO4)CC1)C(=O)CO2 +CCC1C(C)OCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +Cc1nc2c(c(-c3ccccc3)n1)CCN(C(=O)c1cccc(Cl)c1Cl)C2 +COc1ccc2nc(NC3=NCC4(CN5CCC4CC5)N3)sc2c1 +Cc1c2c(n(-c3ccc(Cl)cc3Cl)c1-c1ccc(C(F)(F)F)cc1)CCN(C1CCCCC1)C2=O +CC(C(=O)OC1C[N+]2(CCc3ccc(F)cc3)CCC1CC2)(c1ccccc1)N1CCCCC1 +CCS(=O)(=O)c1ccc(NCC2CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +COc1ccc(NC(=O)C(=O)Nc2ccccc2OC)c(C(=O)Nc2ccc(N3CCOCC3=O)cc2)c1 +c1ccc(C2CN3CCCC3c3cc(OCCCN4CCCCC4)ccc32)cc1 +CC1CN(Cc2ccc(-c3cccnc3S(=O)(=O)N3CCC(Nc4ccccc4F)CC3)cc2F)CC(C)N1 +O=C(NC1CCN(C(c2cnccn2)c2ccc(F)cc2F)CC1)C1CCCCC1 +CCNc1ncc(-c2ccc(Oc3ncc(NC(=O)Nc4cc(C(F)(F)F)cnc4-c4ccc(C)cc4)cn3)cc2)s1 +CCN1CCN(c2ccc(Nc3ncc4scc(-c5cccc(NS(C)(=O)=O)c5)c4n3)cn2)CC1 +CSc1cnc(OCCOc2ncnc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2-c2ccc(C)s2)nc1 +CCNc1cc(-c2cc(C(F)(F)F)nc3c(-n4cnc(-c5cnn(C)c5)c4)cccc23)ccc1C(N)=O +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NCCc1ccccc1 +O=C(c1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)cc1)N1CCCC1 +Cc1cnc2c(C(F)(F)F)cccc2c1-c1cccc(Oc2cc(F)cc(S(C)(=O)=O)c2)c1 +CC1CCN(C(=O)C(Cc2cccc(C(=N)N)c2)NS(=O)(=O)c2cccc(NC(=O)CCN)c2)CC1 +COC1OC2(c3ccc(F)cc3)CCCC3CCCCC31OO2 +CN(C)CCCNc1nc2ccccc2c2[nH]c3ccccc3c12 +CC1(C)CC(N)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C1 +O=c1[nH]c2ccccc2n1C1CCN(C2CCN(Cc3ccccc3C(F)(F)F)CC2)CC1 +Cc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)NC4CN(C)C4)cc3Cl)nc1-2 +CCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 +CCOC(=O)CCC1=C(n2ccc3ccccc32)c2ccccc2C(=O)C1=O +CN1C2CCC1C(C(=O)Oc1ccc(Cl)cc1)C(c1ccc(Cl)cc1)C2 +Nc1ccccc1NC(=O)c1ccc(C(C(=O)NCc2ccccc2)C(=O)NCc2ccccc2)cc1 +Cc1cc(Cl)nc(C)c1C(=O)NCCC(C)N1CCC(N2C(=O)N(C3CCCCC3)CC2c2ccccc2)CC1 +Nc1nc2ccc(O)nc2n1C12CC3CC(CC(C3)C1)C2 +O=C(NCc1ccc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cn1)N1Cc2ccncc2C1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)C1CCOc2c1ccc[n+]2[O-] +Cn1c(CNc2cccc(C(=O)NCc3ccccc3)c2)nnc1-c1ccncc1 +Cc1nnc(CNC(=O)C(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)o1 +O=C(NCCCN1CCC(Cc2ccccc2)CC1)c1ccc2cc(Br)ccc2c1 +N#Cc1cc(-c2ccccc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1 +Cc1cc(Nc2cc(N3CCOCC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 +c1ccc2c(c1)CCN(CCCc1nc3ccccc3s1)C2 +O=C(NC1CCOCC1)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c(F)cc(C3=CCOCC3)cc12 +O=C(C1CC(N2CCN(c3ccc(C(F)(F)F)cn3)CC2)CN1)N1CCC(F)(F)C1 +Cc1cc(=O)oc2c1ccc1oc(=N)c(C(=O)N3CCOCC3)cc12 +CCc1ccc(C2CC(NC(=O)N(C)c3ccccc3)CN(C(=O)C3CCCC3)C2)cc1 +O=c1c2ccccc2nnn1CCN1CCN(c2cccc3ccccc23)CC1 +COc1cc(-c2cnn(CCN3CCN(C)CC3)c2)ccc1Nc1ncc2ccnc(NC3CCCCC3)c2n1 +Cc1cc(C(=O)N2CCc3cccn3-c3ccccc32)ccc1CNC(=O)N1CCCC1C(=O)N(C)C +COc1ccc(NS(=O)(=O)c2ccc(-n3cccn3)cc2)cc1N1CC(C)NC(C)C1 +CN(C)C(=O)c1cn(-c2cc3c(=O)n(NS(C)(=O)=O)c(=O)[nH]c3cc2C(F)(F)F)cn1 +CC(=O)Oc1ccc2c(c1)C1c3cc(OC(C)=O)ccc3C(C2)N2CCCC12 +Cc1nc(C)n(-c2cc(C3CC3c3nc4ccccc4n3C)nc(C3CC3)n2)n1 +CCCNS(=O)(=O)c1c(C(N)=O)[nH]c2ccc(Br)cc12 +O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(c2ccccc2)C(F)(F)F)cc1 +CNC(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2OC)CCCC(N2CCN(CCO)CC2)C3)ncc1Cl +N=C(N)NC(=O)c1ccc2c(c1)C(F)c1ccccc1-2 +CCc1ccc(C2Nc3ccccc3-n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c32)o1 +Cn1c(SCCCN2CCOC(c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccc(-c2ncco2)cc1 +CC(C)CN1CCc2c(cccc2Oc2ncccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)C1 +Cc1cc(C=CC#N)cc(C)c1Nc1ccc(F)c(Nc2ccc(C#N)cc2)n1 +CC1(NS(=O)(=O)c2ccccc2-c2ccc(-c3ccc(N)nc3)c(F)c2)CCC1 +Cn1ncc(NC(=O)c2ccc(F)c(-c3c(F)cc(C(CO)CO)cc3F)n2)c1C1CCC(N)C(F)CO1 +COc1cccc(-c2cn(C)c3c(NN=Cc4ccncc4)ncnc23)c1 +O=C(O)CCCCc1nc2cc(C3=NOC4(C3)Cc3ccccc3C4)ccc2c(=O)n1-c1ccc(F)cc1 +Cc1cc(C)c(-n2c3ncccc3n3c(CN(CC4CC4)CC4CC4)c(C)nc23)c(C)c1 +O=c1c(-c2ccccc2)c2ccccn2c(=O)n1CCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +COc1cc(OC2CCN(C(C)=O)CC2)ccc1CC(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2NCC2CC2)c2cc[nH]c2c1=O +COc1ccccc1-c1ccc(CC(NC(=O)C2(S(=O)(=O)c3ccccc3)CCN(c3ccccc3)CC2)C(=O)O)cc1 +COc1ccc(C=C2C(=O)N(C(=O)c3ccccc3O)N=C2C)cc1OC +CC(C)CNC(=O)c1cnc(NCCCN2CCCCC2C)nc1NCC1CCCCC1 +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1Cc1cccc(NS(C)(=O)=O)c1 +COc1ccc(NC(=O)c2ccc(C)c(Nc3ncnc4cnc(-n5cnc(C)c5)nc34)c2)cc1C(F)(F)F +CCN(CC)CCCOc1ccc2nc3n(c(=O)c2c1)CCC3 +O=C(O)C1(CCCCn2cnc3c2NC=NCC3O)Cc2ccccc2C1 +CC(C)N(CCNC(=O)C1c2ccc(OCc3ccccc3)cc2CCN1C(=O)Cc1ccccc1)C(C)C +CCOc1ccnc2ccc(C#CCNC(=O)c3cccn(Cc4ccc(F)c(F)c4)c3=O)cc12 +COc1cc(OCc2csc(Cl)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccncc3)c2)s1 +O=C(C1CCCN(c2ccc3nc(-c4cnn(-c5ccccc5)c4)[nH]c3n2)C1)N1CCCC1 +Cc1nn(C)cc1-c1nc2c(Oc3ccc(C(=O)Nc4ccccc4)cc3)ccnc2[nH]1 +COc1cc(CCNC(C)COc2c(C)cc(Br)cc2C)ccc1O +Cc1nnc(NC(=O)c2cc(C3CC3NCC3CC3)c(C)s2)s1 +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)N1CCOCC1)c1ccc(F)cc1F +CNC(=O)c1cnc(C(=O)CCc2ccc(Oc3ccccc3)cc2)o1 +CCn1cnc2c(-c3ccc(F)c(-c4ccc(S(=O)(=O)CC)cc4)c3)cnnc21 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCCCCC(=O)NO +Cc1ccc(C(=O)Nc2cccc(C(C)(C)C)c2)cc1Nc1ncnc2c(N)nc(N3CCN(C)CC3)nc12 +O=C(Nc1cnccc1Cl)N1CCN(Cc2cccc(Oc3ccc(F)cc3)c2)CC1 +Cc1ccc2c(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c[nH]c2c1 +C[S+]([O-])c1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +OC1(c2ccc(Cl)cc2)c2cccc3cccc(c23)C2=NCCCN21 +CC(C)(C)OC(=O)N1Cc2[nH]c3ccccc3c2CC1C(=O)NCCCCCCNc1c2c(nc3ccccc13)CCCC2 +Cc1cc2c(c([N+](=O)[O-])c1)N(C)C(=O)c1cccnc1O2 +O=C(Nc1cccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)c1)c1ccccc1 +CN1CCC23Cc4c(c5ccccc5n4C)CC2(Cc2ccc(O)cc23)C1 +CC(C)n1cnc2c(NCc3ccc(-c4ccc(F)cc4)s3)nc(NC3CCC(N)CC3)nc21 +COc1ccc(Nc2nn3c(-c4ccncc4)nnc3s2)cc1 +Cn1nc(C(F)(F)F)cc1-c1cnc2[nH]c(-c3c(F)cccc3F)cc2c1 +O=C(C=Cc1ccco1)NC(=S)Nc1cccc(-c2nc3ccccc3o2)c1 +O=C(O)c1ccc(-c2cccc3c(CCCOc4cccc5ccccc45)c(C(=O)O)nn23)cc1 +COc1cc2c(cc1C(C)NCCc1ccccc1)CCC(C)(C)O2 +CC(C)(C)c1cn(C2=NCC(=O)N3CCc4c(cccc4C4CCCO4)C3=C2)cn1 +CCc1ccc(S2=NS(=O)(=O)c3cc([N+](=O)[O-])ccc32)cc1 +CC(=O)N1CCN(c2ncnc(C)c2C#Cc2cnc(C)c(NS(=O)(=O)c3ccc(F)cc3F)c2)CC1 +CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC#N)cc1 +Cn1cnc2ccc(N3CCCC(OCC(O)CN4CCc5ccccc5C4)C3)cc21 +COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C(=O)N2 +CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1cccc2ccccc12 +COc1cccc2c1C(CCCN1CCN(c3cccc(C(F)(F)F)c3)CC1)=CCC2 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(C2CCOCC2)c(-c2cncnc2)c1 +COc1ccc(-c2cc(OC)cc(C(C)C#Cc3c(C)nc(N)nc3N)c2)cc1 +C[n+]1ccc(Nc2ccc(C(=O)c3ccc(N(CCO)CCO)cc3)cc2)c2ccccc21 +COC(=O)C1CC(OC(C)=O)C(=O)C2C(C)(CCC3CCOC3)C(C(=O)O)CCC12C +Cn1cc(Cc2cn(CCCC(=O)N3CCN(c4ccc(Cl)c(Cl)c4)CC3)c(SCc3ccc(F)cc3)nc2=O)cnc1=O +O=C(NCc1cocn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1CCCC2)c1ccc(C(F)(F)F)nc1 +Cc1cccc(S(=O)(=O)NC2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)C2)c1 +CC1CCC2C(C)C(OCCNc3ccc(Nc4ccnc5cc(Cl)ccc45)cc3)OC3OC4(C)CCC1C32OO4 +Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccccc3F)C2=O)cn1 +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CCCC2C(=O)Nc2ccc(C(=O)O)cc2)cc1 +Cn1c(N2CCCN(CCCN3c4ccccc4CCc4ccc(CC(=O)O)cc43)CC2)cc(=O)n(C)c1=O +CC(C)=CCc1c(O)ccc(-c2coc3c(CC=C(C)C)c(O)cc(O)c3c2=O)c1O +COc1ccc(P(=O)(OCC2CCCCC2)N2Cc3ccccc3CC2C(=O)NO)cc1 +CCC(C(=O)NO)N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 +O=c1c(-c2ccccc2)c[nH]c2c(-c3cccc(Br)c3)cnn12 +CCC(OC(Cc1ccccc1)C(=O)N1CCC(OCOC)CC1)C(=O)NC(CC1CCCCC1)C(O)C(O)CC(C)C +CN(C(=O)c1ccccc1)c1ccc2c(c1)nc(NC(=O)c1ccoc1)n2CCC(N)=O +Cc1cccnc1-c1cc(N2CCC(C(=O)NCCc3c[nH]cn3)CC2)ncc1Cl +CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)C2CC=C(C)CC32)CC1(Cl)Cl +CCC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(OC)c1)CC1C(C(=O)O)C1(C)C +CCc1cc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O +O=C1N(CCCCCCCOc2ccc(Br)cc2)CCN1c1ccncc1 +CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCC1)CC2 +O=C(c1cc(COCc2ccccc2)on1)C1CCCN1C(=O)C1CCCN1C(=O)CCCc1ccccc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1NCC1CCNCC1 +O=C(c1ccc(C2=CC3(CCNCC3)Oc3ccccc32)cc1)N1CCOCC1 +O=C(O)Cn1nnc(-c2cnc(N3CCN(c4cc(F)ccc4Cl)CC3)s2)n1 +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCc2ccccc2C1 +Cc1cc(Br)c(Oc2cc(Nc3ccc(C#N)cc3)n[nH]c2=O)c(Br)c1 +CC(=O)C1CCC2C3CCC4CC(O)(C#Cc5ccc(N(C)C)cc5)CCC4(C)C3CCC12C +CC1(C)OC2OC(COS(N)(=O)=O)C3OC(C)(C)OC3C2O1 +CN1C2CCC1C(C(=O)N1CCCC1)C(c1ccc(I)cc1)C2 +COc1ccc(CN2CCN(CC=C(C)C)C(CCCO)C2)cc1 +CN1Cc2cc(-c3ccc(CC(C#N)NC(=O)C45CCC(CC4)CN5)cc3)ccc2C1=O +O=C(CCNC1CCCCC1)NC(c1ccccc1)C1CCCCC1 +Cc1cccc(CNC(=O)c2cc(-c3nnn(CC4CCC(CO)CC4)n3)cc(C)n2)c1 +Cc1cc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)no1 +NC(=O)c1nc(NC2CCNC2=O)nc(-c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2NS(=O)(=O)c1cccc(C(F)(F)F)c1 +CN(CC(CCN1CCC(c2cccc(C(F)(F)F)c2)CC1)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 +Cc1nc(-c2cccc(C(=O)NC3CCC(CCN4CCc5ccc(S(C)(=O)=O)cc5CC4)CC3)c2)no1 +COC(=O)CCc1ccc(S(=O)(=O)n2c(C3(O)C=CC(=O)C=C3)cc3ccc(F)cc32)cc1 +CNc1c(-c2ccc(=O)n(-c3ccccc3C)n2)c(-c2ccc(F)cc2)nn1C +c1ccc2c(N3CCC(Oc4nccnc4C4CCOCC4)C3)nccc2c1 +O=C(C=Cc1cccc2ccn(Cc3ccccc3-c3ccccc3)c12)NS(=O)(=O)c1cccs1 +O=C(NO)c1ccc(Cl)c(C(=O)Nc2ccc(Cl)cc2)c1 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(CCCN4CCCC4)cc3)nc12 +COc1cc(CNc2nc(C)cc(NC3CCCCC3)n2)cc(OC)c1OC +COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(I)cc(OC)n1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccc(O)cc1 +CC(=O)N1CCN(CCC=Cc2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 +COc1cc2nc(N3CCN(c4ccc(OC(C)C)nn4)CC3)nc(N)c2cc1OC +CC1CCC(C(C)(NC(=O)c2ccsc2)c2cn(C3(C#N)CC3)nn2)CC1 +CN(CCc1cccc(OC(F)(F)F)c1)CCN1CCCC1 +CC(C)(C)c1cc(C(=O)N2Cc3ccccc3C2)ccc1O +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c(F)cc(N3CCOCC3)cc12 +O=C1c2ccccc2C(=O)N1CCOC(=S)N(C(=O)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)cc1 +COc1cccc(-c2cc(C#N)ccc2C#CC(O)c2cncn2Cc2ccc(C#N)cc2)c1 +Cc1nc(NC(C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc3ncsc3c2)n1 +O=C(C1CC1c1ccc(-c2cn[nH]c2)cc1)N1CCN(C2CCC2)CC1 +O=C1c2cc(COc3ccccn3)nn2CCN1c1ccc(F)cc1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCCN1CCCC1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1-c1cnco1 +Nc1cnc(-n2c(C(Nc3ncnc(N)c3Cl)C3CC3)nc3cccc(Cl)c3c2=O)cn1 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccc(C(=O)O)cc3)cc21 +COc1cccc(Cn2ccc3ccc(-c4ccc5ccn(Cc6cccc(C(=O)O)c6)c5c4)cc32)c1 +CN1CCN(C(=S)NCCCNc2ccnc3cc(Cl)ccc23)CC1 +Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cccc(F)c2)n1 +CC(C)(C)c1cc(Nc2cc(-c3ccc(OC4CCOCC4)c(C#N)c3)ccn2)on1 +COc1ccc(NC(=O)Nc2nc3nn(C)cc3c3nc(-c4ccco4)nn23)cc1 +Cc1cccc(C)c1NC(=O)Nc1nc2ccccc2n1-c1ccccc1Cl +CCOc1ccccc1-c1ccc(-c2nc3ccc(F)cc3c(NC(Cc3ccccc3)C(=O)O)c2C#N)cc1 +COc1ccc(F)c(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)c1 +CC1NC(=O)c2cc(-c3cccc4c(=O)n(C5CCOCC5)c(NC(C)(C)C)nc34)[nH]c21 +Cc1nc2ccc(F)cc2c(=O)n1-c1ccc(OC2CCN(C3CCC3)CC2)cc1 +COc1cccc(C=NNc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c1 +O=C(NC1CCCCC1)c1cn(Cc2ccccc2)c2ccccc2c1=O +CC#CCCn1ncc2c(N)c(C(=O)NCC3CC3)cnc21 +CS(=O)(=O)c1ccc2c(Sc3ccc(F)cc3)c(CO)[nH]c2c1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(-c5ccccc5)cc4)cc3)cc2n(CCC)c1=O +CCCn1nc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c2cccnc21 +CCN(CCCCCCNC(=O)c1cc(=O)c2c(O)cccc2o1)Cc1ccccc1OC +O=C(CC1CCCCC1)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +N#Cc1ccc(NS(=O)(=O)c2ccccc2C(F)(F)F)cc1 +O=C(O)Cc1cccc2c(OCc3cccc(-c4c(Cc5ccccc5)cnc5c(C(F)(F)F)cccc45)c3)cccc12 +COc1cc(N2CCN(C)CC2)ccc1Nc1nccc(-c2c[nH]c3cnc(C)cc23)n1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1cnc(C(F)(F)F)cc1Cl +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCc1ccc(O)cc1 +COc1ccc(S(=O)(=O)Nc2ncccc2Nc2ccc(O)cc2)cc1 +Cc1ncc([N+](=O)[O-])n1CC(C)OC(=O)C=Cc1cccc2ccccc12 +O=C(Cc1ccc(O)cc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccnc3)s2)s1 +CC1CN=C2N(C)C(=O)c3c(nn(Cc4ccc(-c5ccccc5)cc4)c3Nc3ccccc3)N21 +CC1OC(=O)C2CC3CC(NS(C)(=O)=O)CCC3C(C=Cc3ccc(-c4cccc(F)c4)cn3)C12 +O=S(=O)(CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1)C1CC1 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+CCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1 +COC(=O)Nc1nc2ccc(Sc3ccccc3)cc2[nH]1 +CNC(=O)c1cc2c(Oc3ccc(-n4cccn4)cc3)cncc2s1 +CSc1ccc2c(c1)CCN2C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 +CN1C(=O)NC2C3NC(=O)c4ccc(I)n4C3CC21O +CC(c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CCC(CC(C)(C)O)(c2ccc(F)cc2)OC1=O +CCSc1nc(-c2ccccc2)c(-c2ccc(S(C)(=O)=O)cc2)[nH]1 +COc1ccc(-c2csc(C(=O)NCCN3CCOCC3)c2)cc1 +CCCC12CCC(=O)C=C1c1c(cc(OCC(=O)O)c(C)c1C)C2 +CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)O)COC3 +COc1ccc(NC(=O)N2CCC(c3c[nH]c4cccc(F)c34)CC2)cc1N1CCN(C)CC1 +COc1cc(-c2cc(C)c3c(OC)ccc(OC)c3n2)cc2c1OCCN(C(=O)CCn1nc(C)cc1C)C2 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2ccc(C(C)=O)nc12 +C=CC(=O)Nc1ccccc1Nc1nc(NC2CCC(N(C)C)CC2)ncc1Cl +O=C1CC2(CCN(C(=O)NC3CCC(c4cccc(F)c4F)CN(CC(F)(F)F)C3=O)CC2)c2cccnc2N1 +Cc1nc(NC(C)c2cccc(OCC(=O)N3CCOCC3)c2)cc(-c2ccc3ncsc3c2)n1 +Cc1cccc(-c2nc3ccccc3nc2OC2CN(c3ccc4ccccc4n3)C2)c1 +CCSC1=C2CCC3C4CCC(=O)C4(C)CCC3C2(C)CCC1=O +CCC#CCOc1nc(-c2ncccn2)nc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1Oc1ccccc1OC +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)CCC +COc1ccc(-c2cnc3[nH]cc(-c4ccc(OC)c(OC)c4)c3c2)cc1OC +CCCOc1ccc(N2CCC(Oc3ccc(C(C)NC(=O)c4sc(NC(C)=O)nc4C)cc3)C2)nc1 +COc1cc2c(cc1O)C1Cc3sc(CC(C)Cl)cc3CN1CC2 +CCCCN(C=Cc1ncnc2c1ncn2C1OC(CO)C(O)C1O)CCCC +O=C(NCc1ccc(S(=O)(=O)c2ccccc2)cc1)c1cn2ccnc2cn1 +CC1(C)Cc2c(sc(NC(=O)c3cc(C(F)(F)F)n[nH]3)c2C(N)=O)C(C)(C)O1 +COCc1nc2c(C(=O)NCc3ccccc3Cl)cc(NC(=O)c3ccccc3C(F)(F)F)cc2n1C +COc1ccc2c3c1OC1C4(OC)CCC5(CC4COCc4ccccc4)C(C2)N(CC(=O)O)CCC315 +N#Cc1cccc(Nc2nc(-c3ccccc3)nc3ccccc23)c1 +CN(C)CCC(Oc1cccc(NC(=O)Nc2ccc3c(ccn3C)c2)c1)c1ccccc1 +Cc1noc(-c2cccc(-c3cc(F)c(C4(C)CS(=O)(=O)N(C)C(=N)N4)s3)c2)n1 +c1ccc(-c2cc(-c3nn[nH]n3)cnc2-c2ccc(CNCc3ccc(-c4csnn4)cc3)cc2)cc1 +NS(=O)(=O)c1cccc(-c2nc(C(c3ccc(F)cc3)c3ccc(F)cc3)sc2CC(=O)O)c1 +Nc1ncnc2c1c(-c1cccc(O)c1)cn2-c1ccc(OCCNCCO)cc1 +N=C1NC(c2ccccc2)(c2cccc(-c3cccnc3)c2)C(=O)N1C1CCCCC1 +Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)Cc3cccc4ccccc34)CC2)n1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC(=N)N)no2)cc1C#N +COC1C(OC(=O)NC(=O)Cl)CCC2(CO2)C1C1(C)OC1CC=C(C)C +CN(C)CCCc1c(C=C2C(=O)Nc3ccc(S(=O)(=O)N4CCc5ccccc54)cc32)[nH]c2c1C(=O)CCC2 +CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc3c(c2)OCO3)cc1 +CCN1CCN(c2cc(C)c3cc(NC(=O)C=Cc4cc(OC)ccc4OC)ccc3n2)CC1 +O=C(NCCSC1c2ccccc2COc2ccc(C(=O)O)cc21)OCc1ccccc1 +CCNc1nc2c(c(C(N)=O)n1)CN(C(=O)CCc1ccc(CC(F)(F)F)cc1)CC2 +CC=C1C2C=C(C)CC1(N)c1ccc(=O)[nH]c1C2 +COc1ccc2c(c1)NC1(CCN(C(=O)c3ccc4c(c3)N(C)CCO4)CC1)c1cccn1-2 +COc1cccc(F)c1C1CC(C)C(=O)N1Cc1ccc2oc3ccccc3c2c1 +COc1c(-c2cnn(C)c2)cnc2c1cc(C(=O)NCc1ccc(Cl)cc1)c(=O)n2CC(=O)N1CCC(CO)C1 +CC1(C)SCCCN(S(=O)(=O)c2ccc(Oc3ccccc3)cc2)C1C(=O)NO +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)c(Br)c2n(CCC)c1=O +CC(C)(C)C(=O)N1CCc2ccc(C(=O)NO)cc2CC1 +CNC(=O)c1ccccc1-c1cnc(Nc2ccc(-c3cnco3)c(OC)c2)o1 +Cc1cccc(-c2noc(C3CN(S(=O)(=O)c4ccc(F)cc4)C3)n2)c1 +N#Cc1cccc(-c2cnc3nnn(CC4CN(c5ncc(-c6cnn(C7CCNCC7)c6)cn5)CCO4)c3n2)c1 +Cc1ccc(Oc2ccc(N(CC(C)(O)C(=O)NO)S(C)(=O)=O)cc2)cc1 +O=C(O)CCc1ccc(C#Cc2ccnc3cc(Cl)ccc23)cc1 +COc1ccc2c(C(=S)N(C)CC(=O)O)cccc2c1C(F)(F)F +CNC(=N)c1cc(C)c2nc(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)[nH]c2c1 +CC1NC(=O)C(C(C)C)NC(=O)CCCCC=Cc2cccc(c2)C(C)OC(=O)C2CCCN(N2)C1=O +CC(=O)Nc1nc2ccc(-c3nn(Cc4cc5cccc(C)c5c(=O)n4C)c4ncnc(N)c34)cc2s1 +CC(=O)N1CCC(c2cccnc2Oc2ccc(Nc3ncccc3F)cc2)CC1 +CCCS(=O)(=O)Nc1cc(Cl)cc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +COc1ccc(F)c(OC)c1C1CC(Cl)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +NC(=O)C(Cc1ccccc1)NC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +Oc1ccnc(-c2ccc(-c3ccc(-c4nc5nc(OC6COC7C(O)COC67)[nH]c5cc4Cl)cc3)cc2)n1 +O=C(NN=Cc1ccc([N+](=O)[O-])o1)c1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +C=C1C(=CC=C2CCCC3(C)C(C(C)CCC(F)(F)C(O)(CC)CC)=CCC23)CC(O)CC1C(F)F +O=S(=O)(c1ccc(C(F)(F)F)nc1)N1C2Cc3[nH]ncc3C1CC(c1ccccc1F)C2 +Brc1ccc2oc(-c3cc[n+](Cc4ccccc4)cc3)cc2c1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3(CO)CC23)c2ncccc12 +COc1ccc(OC)c(N(C)c2nc(Cl)nc3ccccc23)c1 +CC(C)CC(=O)Nc1nc(-c2ccccc2)cc(-c2ccccc2)n1 +Nc1nc2c(ncn2CC(COCCP(=O)(O)O)OCCP(=O)(O)O)c(=O)[nH]1 +COc1ccc(C2(OC(C)C)SC=C(C)n3c2noc3=O)cc1 +O=C(Nc1cccc(C(F)(F)F)c1N1CCOCC1)c1cccc(-c2ccccn2)c1 +CCCCCC=CCC=CCC=CCCCCC(=O)NCCc1c[nH]c2ccc(O)cc12 +CCc1cnc(N2CCC(n3ncc(COc4ccc(-n5cnnn5)cc4)c3C#N)CC2)nc1 +O=C(CN1CCCCC1)N1c2ccccc2Oc2ccccc21 +COc1cccc(-n2ncc3c(NN=Cc4cccc(N)c4)ncnc32)c1 +O=C(NCCN1CCOCC1)c1ccc(F)c(NCc2cnc(Nc3ccccn3)s2)c1 +CCOc1cc(Cl)c(Cc2ncc(-c3ccoc3)s2)cc1C1OC(CO)C(O)C(O)C1O +COc1cccc(NC(=O)Nc2ccc(-c3ncnc4[nH]cc(C)c34)cc2)c1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C(F)(F)F)nn3)c2)c2cnccc21 +CCc1nn(C2CCCC2)c2c1CCN(Cc1ccccc1)C2=O +CCc1nc(N)nc(N)c1-c1ccc(Cl)c(N=NN(CCOC(C)=O)Cc2ccccc2)c1 +CCc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(C=Cc5ccccn5)n[nH]c4c3)c2)n(C)n1 +CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCCC3COC)ccc21 +Cn1cncc1C(c1ccc2c(c1)c(-c1cccc(Cl)c1)nc1nnnn12)n1ccnc1-c1ccc(F)cc1 +O=C(NCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1)c1ccc(F)cc1 +O=C(O)C1CCCN(CCOC=Cc2ccccc2Cc2ccccc2)C1 +Cc1ccc(Cc2ccc3c(c2)C2(OC3)OC(CO)C(O)C(O)C2O)cc1 +CN1Cc2cnc3ccc(-c4cnc5ccccc5c4)nc3c2N(c2ccc(C(C)(C)C#N)cc2)C1=O +Cc1c(-c2ccc3cc(NC(=O)C4CC4)ncc3c2)cnc(CO)c1F +COc1cc(C=C2SC(=O)N(Cc3ccc(F)cc3)C2=O)ccc1OCc1ccc(C(=O)O)cc1 +CNC(=S)OCC1OC(n2cnc3c(NC4CCOC4)nc(Cl)nc32)C(C)(O)C1O +O=C(CCN1CCN(Cc2ccc(Cl)cc2)CC1)N1CCc2ccccc21 +CNCCCN1Cc2ccccc2N(c2ccc(Cl)cc2)S1(=O)=O +CC1OC(OCc2cc(O)c3c(c2)C(C2OCC(O)C(O)C2O)c2cccc(O)c2C3=O)C(O)C(O)C1O +CCc1nc(NCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c2cc(OC)ccc2n1 +Cc1cn(CC(N)C(=O)O)c(=O)n(Cc2ccsc2C(=O)O)c1=O +CCOC(=O)c1c(NC(=O)NS(=O)(=O)c2ccc(C)cn2)sc2c1CCC(C)(C)C2 +CC(C)C(NS(=O)(=O)c1ccc2c(c1)sc1cc(NC(=O)Nc3ccccc3)ccc12)C(=O)O +O=C(Cc1ccccc1)c1ccc(CN2CCC(C(=O)O)C2)cc1 +Cc1cc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)cnc1Oc1ccnc(NC(=O)C2CC2)c1 +Oc1cccc(C23CCN(CCc4ccccc4)C(CC(c4ccccc4)C2)C3)c1 +Cc1cc(OCP(=O)(O)O)cc(C)c1Cc1ccc(O)c(-c2ccccc2)c1 +CCC(=O)Nc1ccc(OCCCNC(C)C)c(Cc2ccccc2)c1 +COc1ccc(C)cc1Nc1nc(N)c2cc(OC)c(OC)cc2n1 +c1ccc(-c2nc(=NCCN3CCOCC3)sn2-c2ccccc2)cc1 +CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(CCN5CCN(CCO)CC5)c4)cc2)CC3)n1 +CC1OC(n2cnc3c(NC4CCCC4)ncnc32)C(O)C1NC(=O)C1(c2ccccc2)CCCC1 +NS(=O)(=O)c1ccc(-c2c(S(=O)(=O)c3ccccc3)no[n+]2[O-])cc1 +Cc1cc(Cl)c(C=CC2CC(O)CC(=O)O2)c(-c2ccc(F)c(C)c2)c1 +Cc1nc(C(C)(CS(C)(=O)=O)NC(=O)c2cc(OCC(F)F)c(C3CC3)cn2)no1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccc1)CC2 +Cc1c[nH]c(CN2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccnc(F)c4)n3)CC2)n1 +COc1ccc(C)c(Nc2cc(C(F)(F)F)nc(-c3ccncc3)n2)c1 +Cc1cc(=O)n(CC(N)C2CCC(NCc3ccc4c(n3)NC(=O)CO4)CC2)c2cc(F)ccc12 +CN1CCN(CC(=O)C(O)(c2ccccc2)C2CCCCC2)CC1 +CCN(CC)CCn1cc(-c2ccc(F)c(C)c2)nc1C1CCN(c2ncnc(N)c2OC(C)C)CC1 +Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 +Cc1cc(C)cc(C(=O)Nc2nccn3c(-c4cccc(NC(=O)Nc5ccc(F)cc5F)c4)cnc23)c1 +CC1CN(Cc2c[nH]nc2-c2c[nH]c(C#N)c2)CCN1c1ccc(C(F)(F)F)cn1 +C#CCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1 +Nc1ncc(CCNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)s1 +COCCOc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCC2)[nH]1 +Cc1cc(NC(=O)C(=O)O)cc(C)c1Oc1ccc(O)c(-c2cccc(F)c2)c1 +COc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 +Cn1cnc(S(=O)(=O)N(CC2CCNCC2)C2Cc3cc(C#N)ccc3N(Cc3cncn3C)C2)c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCC(O)CC4)cc3OC)ncc2Cl)c1 +COc1cc2nc3c(c(N)c2cc1OC)CCC(CNC(=O)c1cccc(C(F)(F)F)c1)C3 +CN(C)CCCNc1ccc2c3c(nccc13)-c1ccccc1C2=O +CCc1nc(Nc2cc(CCc3cc(OC)cc(OC)c3)[nH]n2)c2ccc(N3CCN(CC)CC3)cc2n1 +CC(C)(C)NC(=O)c1c[nH]c2ncc(Nc3ccc(S(C)(=O)=O)cc3)nc12 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(c2ccncc2)C1 +Cc1ccc2c(c1)N(c1ccc(NCCc3ncc[nH]3)cc1)C(=O)N(C1COc3ccccc3OC1)N=C2C1CCCCC1 +CC(C)(C)c1nc(COc2ccc(C=NNC(=O)c3ccc(O)c(Cl)c3)c3ccccc23)no1 +CN1CCc2cc(Cl)c(O)cc2C2c3cccc(CO)c3CCC21 +COc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(=O)c1cccc(CO[N+](=O)[O-])c1Br)CC2 +O=C(NC1CCN(CC(O)CN(Cc2ccccc2)S(=O)(=O)c2ccccc2)C1)c1cccc2ccccc12 +CN(C(=O)Cc1ccc2ccccc2c1)C1CCCCC1N1CCCC1 +COC(=O)C1(NC(=O)c2ccc(NC(=O)C(=O)c3ccccc3NC(C)=O)cc2)CCCC1 +O=C1NC(=S)N(c2ccccc2)C(=O)C1=Cc1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1-c1ccccc1 +Cc1cc(Nc2cc(OCCN3CCOCC3)nc(NCc3cc(-c4ccccc4)no3)n2)[nH]n1 +CS(=O)(=O)c1ccc(-c2nc(NC3CCCC3)cc(C(F)(F)F)n2)cc1 +CC(NS(=O)(=O)c1ccc(Cl)cc1)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1 +COc1cccc(-c2cnc3[nH]cc(-c4ccncc4)c3c2)c1 +COc1cc(C)cc2c1C(C1CCN(C(=O)Cc3cc[n+]([O-])cc3)CC1)c1ncccc1CC2 +O=C1Nc2cccnc2N(C(=O)CC2CCCN3CCCCC23)c2ccccc21 +O=C(NC1CCCN(c2ncnc3[nH]ccc23)C1)C(Nc1ccccc1)C1CC1 +OC(Cc1nc(CC2(C(F)(F)F)CC2)c[nH]1)(c1ccc(-n2cccn2)cc1)C(F)(F)F +O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc2c(c1)nc(O)n2Cc1ccc(F)cc1 +Cc1onc(-c2cccc(Cl)c2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 +Cc1c(-c2ccccc2F)c(=O)n(CC(N)c2ccccc2)c(=O)n1Cc1ccccc1F +CCNC(=O)c1cc2c(-c3cc(OCCN(C)C)c(Cl)cc3Cl)nc(N)nc2s1 +COCCNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC)ncc1Cl +CCCCN(C(=O)C1=COc2cc(O)c(C(C)(C)C)cc2O1)c1ccccc1 +Cc1c(NC2CC2)nc(C2CCC2)nc1N1CCCCCC1 +COc1cccc(C(=O)Nc2cccc(-c3nc4sccn4c3-c3ccnc(Nc4ccc(N5CCOCC5)cc4)n3)c2)c1 +O=C(NCc1ccccn1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC3CCCC3)n1)CCN2 +Cc1cn(Cn2cnc(-c3cnn(C)c3)c2-c2ccc(C#N)cc2F)nn1 +CC(C)CC(NC(=O)C(C)NC(=O)CC(O)C(COCc1ccc(Br)cc1)NC(=O)c1ccc2c(c1)OCO2)C(N)=O +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5CCCC(C4)N5)cn3)nc2n1C1CCCC1 +COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(C4(CN5CCCC5)CC4)cc2)CC3)cc1 +CC(C)(C)c1cc(C=NNc2nc3ccccc3[nH]2)cc(C(C)(C)C)c1O +Cc1ccc(-c2ccc(C(C)CNS(=O)(=O)C(C)C)cc2)cc1 +O=C(Nc1cn(CC(=O)N2CCC(C(=O)O)CC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +NCCCCCCCCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +CCCOc1cccc2c1cnn2-c1ccnc(NC2CCC(O)CC2)n1 +CC1CN(CC2CCOCC2)CCN1C(=O)N1Cc2c(NC(=O)c3ccc(F)cn3)n[nH]c2C1(C)C +Cn1cc(-c2cnc3ccc4ccc(NS(C)(=O)=O)cc4c(=O)c3c2)cn1 +COc1ccc2c(c1)NC(=O)Cc1c-2[nH]c2ccc(C(F)(F)F)cc12 +O=C(NCc1ccc(Cc2cccc(Cl)c2)s1)C(O)C(O)C(=O)N1CCCC1c1cccc(Cl)c1 +Cc1cccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)c1 +O=C(O)CCC=CCC1COC(c2ccc3cc(C(=CCCCCC(=O)O)c4cccnc4)ccc3c2)OC1c1ccccc1O +Cc1[nH]c(-c2ccccc2Oc2ccccc2)c2cc[nH]c(=O)c12 +CC(Nc1nccc(-n2cnc3ccccc32)n1)c1ccccc1 +COc1ccc2c(c1NS(C)(=O)=O)CCCC2c1c[nH]cn1 +COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(C(F)(F)F)cc2NC(=S)C1c1ccc(Cl)cc1 +CCCCn1nc(C2(C)CC2)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ONC(C)(C)C +Cc1ccc(-c2cc(C)c(C(=O)N=C(N)N)cc2S(C)(=O)=O)cc1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)NCC3CC3)cc2F)cn1 +O=C(O)C(Cc1ccc2cc(OCCCN3CCNCC3)ccc2c1)NS(=O)(=O)c1ccc(F)cc1 +CCc1nc(C)n2nc(O)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN1CCC(c2c[nH]c3cnc(NC(=O)c4ccc(F)cc4)nc23)CC1 +COCC(O)COc1ccc(OCc2cccc(Cl)c2)cc1C(C)=O +O=C1c2ccccc2CCC1CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1 +OC1CCN(Cc2ccc(F)cc2)CC1N1CCC2(CCCc3ccccc32)CC1 +COCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCNC(C)=O)C(C)C)ccc1OC +O=C(O)c1ccc2occ(C=NNc3nc4c(c(N5CCOCC5)n3)CSCC4)c(=O)c2c1 +COC1CCC(CC(=O)NC2CCC(CCN3CCC(c4cccc5c4OCO5)CC3)CC2)C1 +NC1Cc2c(ccc3cc(N4CCOCC4)ccc23)OC1c1cc(F)c(F)cc1F +COCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3ccc(F)cc3Cl)cc2[nH]1 +FC(F)(F)c1cccc(N2CCN(CCCN3CC4CCCN4C3)CC2)c1 +Cc1cc(S(=O)(=O)Nc2cc(Cl)c(Oc3cnc4ccccc4c3)c(Cl)c2)ccc1Br +O=C(NN1CCOC1=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1 +CC(C(O)c1ccc(O)cc1)N1CCC(O)(c2ccc(Cl)cc2)CC1 +O=C(NCC1CCNCC1)c1cc(F)ccc1-c1cccc(Cl)c1 +Cc1c2c(n3c1CCN(C(=O)C(C)(C)N)CC(C)C(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +CCOC(=O)Nc1cc(-c2ccc(C)cc2NS(C)(=O)=O)nn2c(C)nnc12 +COCCCOc1ccc(-c2nccc(-c3cc4c([nH]3)C3(CCCNC3)CNC4=O)n2)cn1 +COc1ccc(-c2nc(NC(=O)NCCC(=O)NO)cc3c2[nH]c2ccccc23)cc1 +CCCS(=O)(=O)CC(CC)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +C=C1C(CO)C(O)CC1n1cnc2c(=O)[nH]c(N)nc21 +CCC(CS(=O)(=O)C(C)(C)C)N1C(=O)C(C)(CC(N)=O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CC(C)Oc1cc2c(-c3cc(N4C5CCC4COC5)ncn3)n[nH]c2cc1F +O=C(Nc1cccc(-c2ccncc2)c1)C(Cc1ccccc1)NCc1cscn1 +Nc1ccccc1NC(=O)c1ccc(-c2cn(CCc3ccsc3)nn2)cc1 +COCCN1CCC(Nc2cnc3ccc(C#CCNC(=O)c4cccn(Cc5ccc(F)c(F)c5)c4=O)cc3n2)CC1 +CN(C)c1nc(N)nc2[nH]c(-c3ccccc3)c(-c3ccccc3)c12 +Cc1ccc2nc(N)nc(O)c2c1Sc1ccc(C(=O)NC(C(=O)O)c2cccc(C(=O)O)c2)cc1 +COc1ccc(S(=O)(=O)N2CCOCCSC(C)(C)C2C(=O)NO)cc1 +Cc1cnc(-c2cc(Oc3ccc(S(=O)(=O)N(C)C)cc3)cc(OC(C)CO)c2)[nH]c1=O +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3c(OC)cc(OC)cc3OC)CC21C +CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2C3CCCC2CC3)cc1 +CC(C)C(NC(=O)OCc1ccccn1)C(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)NC(=O)OCc1ccoc1 +CSc1nc(NCC2CCCCC2)c(C(=O)O)c(SCc2ccccc2)n1 +Cc1cc(C2CCN(C(=O)C3CN(C(C)(C)C)CC3c3ccc(F)cc3F)CC2)n(-c2ccc(Cl)c(C)c2)n1 +CN1CCC(COCc2cc(C(F)(F)F)ccn2)(c2ccc(F)cc2)CC1 +COc1cc(-c2cnc(C)n2C)ccc1Nc1cc2cc(-c3cnn(C4CCOCC4)c3)ccc2cn1 +CC(C)c1ccc(-c2noc(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)n2)cc1 +CCN(CC)CCOc1ccc2c(c1)C(C)(C)c1sc3ccccc3c1C2=O +NS(=O)(=O)c1ccc2c(c1)CCN2C(=O)C(F)(F)F +CS(=O)(=O)c1ccn2cc(-c3ccc(-c4ccccc4)cc3)nc2c1 +Cc1ccc(-c2nc(NC(=O)CN3CCN(C)CC3)cc(-n3nccc3C)n2)o1 +Nc1nn2cccnc2c1C(=O)Nc1cn(CC(=O)N2CCC(F)(F)C2)nc1-c1cc(Cl)ccc1OC(F)F +COCCN1CCCC(n2nc(C(=O)N3CCOCC3)c3c2-c2cccc(OC)c2S(=O)(=O)C3)C1 +CCCCN1CC=C(c2c(C)[nH]c3ccc(Cl)cc23)CC1 +Cn1c(=O)ccc2cc(NS(=O)(=O)c3cccc(C#N)c3)ccc21 +CC12CCC3C(CC(c4ccc(O)cc4)C4=CC(=O)CCC43C)C1CCC2=O +O=C(CCN1CCCCC1)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +Cn1cc(C(=O)N2CCCC3c4ccccc4CCC32)c2ccccc21 +CCCCOc1ccc(C(=O)Nc2ccc3nc(SCc4c(C)cc(C)c(C(C)=O)c4C)sc3c2)cc1 +Cc1ccc(Cl)c(C(=O)NCC(c2ccc(F)cc2)N2CCOCC2)c1 +CC(=Cc1cccnc1)c1ccc(C(=O)N=c2[nH]c3cc(N(C)C(=O)c4ccccc4)ccc3n2CCC(N)=O)s1 +C=CCNc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n3n2CCC3)n1 +N#CC1(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)CC1 +CN(C)CCNc1cc(-c2ccc(N3CCCCC3)cc2)nc2ccccc12 +Fc1cc(F)c(OC2CCN(c3nc4cnccc4nc3NC3CC3)CC2)c(F)c1 +Cc1cn(-c2ccc(-c3ccc(NC(C)c4ccc(F)cc4)nc3)cc2Cl)cn1 +CCCC1C(=O)Nc2nc(-c3ccc(OCC(=O)NC4CC(C)(C)N([O])C(C)(C)C4)cc3)[nH]c2C1=O +O=C(Nc1c(F)c(F)c(-c2cccc(C(F)(F)F)c2)c(F)c1F)c1nonc1O +OCC1OC(c2ccc(Cl)c(Cc3ccc(OCC4COC4)cc3)c2)C(O)C(O)C1O +O=C(O)CCNC(=O)c1ccc(-c2cc(C(F)(F)F)ccc2CNc2ccc(-c3ccc(Cl)cc3Cl)c(Cl)c2)cn1 +CSc1c(Cl)nc(-c2ccc(NC(=O)Nc3ccc(S(C)(=O)=O)cc3)cc2)nc1N1CCOCC1 +CCCCC(=O)c1c[nH]c2ccc(Cc3ccncc3)cc2c1=O +CC(C)N(c1c(F)c(Oc2cccc(C(=N)N)c2)nc(Oc2ccc(Cc3ccccc3)cc2C(=O)O)c1F)C(C)C +NS(=O)(=O)c1nnc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)s1 +COC1CCC2(CC1)Cc1ccc(-c3cnn(C)c(=O)c3)cc1C21N=C(N)N(C)C1=O +CCCCN(CC)c1ncnc2c1nnn2-c1ccc(C(C)C)cc1Br +CC(C)(C)c1ccc(NCC(O)CON=C(C2CC2)C2CC2)cc1 +O=C(Nc1ccc(CC(N=c2c(O)c(O)c2=NCCCC(F)(F)F)C(=O)O)cc1)c1c(Cl)cncc1Cl +CCS(=O)(=O)N1CCC(N(C)C(=O)NC2CCN(c3cc(F)cc(F)c3)CC2)CC1 +Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N(C)C)cc1 +O=C(NCCCC1CCN(CC2COc3ccccc3O2)CC1)Nc1ccccc1 +CC(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccsc3)cc1)C2=O +N#CCCCOc1ccc(-c2ccc(-c3ccccc3)n2CC(=O)NC(=N)N)cc1 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NC2CCCCC2O)cc1 +O=C(NCC1(O)COC1)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +CC(C)n1cnc2c(NCc3ccc(-c4ccccc4)cc3)nc(NC3CCC(N)CC3)nc21 +N=C(N)N1CCCC(NC(=O)CNC(=O)C(CCNC(=O)c2cncc(Br)c2)NS(=O)(=O)Cc2ccccc2)C1O +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3cccc(CN(C)C(=O)C4CCC4)c3)nc2n1 +CCOC(=O)C(=O)Nc1cc(C)nc(N2CCc3ccccc3C2)c1 +FC1(c2cn(-c3ccc(Br)cc3)nn2)CN2CCC1CC2 +Cn1cc(-c2ccc(Cc3n[nH]c4ccc(C(=O)N5CC(O)C5)cc34)cc2)cn1 +C=CCN1CCCC1CNC(=O)c1cc(CCCCl)cc(OC)c1OC +CCN1C(=O)CCCC1C(=O)NCc1ccc(F)c(F)c1F +OCC1NC(C(O)CCCCC2CCCC3(CCCO3)O2)C(O)C1O +NC(CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1)C1CCCCC1 +COc1ccccc1-c1c[nH]c2ncnc(-c3ccccc3)c12 +CCCCCS(=O)(=O)NC(=O)C=Cc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl +COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2cccc(F)c2)CC2CCC1C2 +COc1cc2c3c(c4ccc(OC(C)=O)cc4c2cc1OC)CN1CCCCC1C3 +COc1cccc(-c2cnn(CC3CCc4c(cccc4OCC(=O)O)C3)c(=O)c2-c2ccccc2)c1 +O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2ncccn2)CC1 +N#CC1CCCN1C(=O)CNC(=O)c1cccc2ccccc12 +CCCCCCCCCCCCCC1=C(O)C(=O)C=C(OC)C1=O +O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCCOc3ccccc3)ccc1-2 +CN1CCc2nc(NC(=O)c3cccc(CNC(=O)c4ccc(-n5ccnc5)cc4)c3)sc2C1 +O=C(Nc1ccc(-c2nc(C3=CCOCC3)c3sccc3n2)cc1)Nc1cccnc1 +CCCc1ccc(C=C2CN3C4CCC3C(C(=O)OC)C2C4)s1 +Cc1nc2nc(C(=O)N(C)CCc3ccccn3)cn2c(-c2ccc(Cl)cc2Cl)c1CN +CCOC(=O)C1CCN(C(=O)CCc2ccc(-c3ccc(CCN4CCCC4C)cc3)cc2)CC1 +CNC1CCN(C(=O)C2CCCCN2S(=O)(=O)c2ccc(-c3ccc(C)o3)cc2)C1 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+O=C(C(Nc1ccccc1F)c1cc2ccccc2s1)N1CCCC1c1ccccc1F +CN(CCOc1ccccc1C(C)(C)C)C(=O)Nc1ccccc1C(=O)O +NC1(c2ccc(-c3nn4c(-c5ccn[nH]5)cnc4cc3-c3ccccc3)cc2)CCC1 +CN(C(=O)C(Cc1ccc(CN)cc1)NS(=O)(=O)c1ccc(-c2ccccn2)s1)C1CCCC1 +COC(=O)C(Cc1ccc(OCCOc2ccc3ccccc3c2)cc1)C(=O)OC +COc1ccccc1C(Cn1c(=O)n(C(C)(C)C(=O)O)c(=O)c2c(C)c(-c3ncco3)sc21)OC1CCOCC1 +COc1ccc(S(=O)(=O)N(Cc2ccc3c(n2)C=CC(C)(C)O3)C2CCCCCCC2)cc1OC +CC#CC(C)(C)Oc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(S(=O)(=O)C(C)C)CC2)cc1 +COc1ccc(-c2cc(CNc3ccc(S(=O)(=O)Nc4nnc(C)s4)cc3)cc(C(=O)NC(CO)CO)c2)cn1 +CS(=O)(=O)N1CC=C(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +N#Cc1ncc(C(=O)NCC(F)(F)F)c(N2CCC(S(=O)(=O)c3cccc(Cl)c3Cl)C2)n1 +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3C4CCC(C4)C3N(Cc3cccs3)C1=O)N2 +CC(C)(C)OC(=O)N1CC2CC1C1(C)C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)N21 +O=C(O)CCc1ccc(-c2c(C=Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cn1 +Cc1cc(Nc2cc(C(F)F)ccn2)nc(-c2ccc(C(C)(O)C3CCC(C(=O)O)C(C)C3)nc2)c1 +Cc1cccc(COc2ccc(S(=O)(=O)C3CCOCC3(O)C(=O)NO)cc2)c1 +COC(=O)c1ccc(Oc2ccc(C=C3SC(=O)NC3=O)cc2OC)cc1C(F)(F)F +CC(C)Oc1cccc(-c2cnnc(-c3ccccc3)c2)c1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCN(C(=O)C2CCCCC2)CC1 +CCC1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 +COc1ccc2c(c1)[nH]c1c3[nH]c4cc(Br)ccc4c3c3c(c21)C(=O)NC3=O +CCCCOc1ccc(S(=O)(=O)N2CC(NC(=O)C(O)CC(C)C)CC2C(=O)NO)cc1 +CCCC(CCC)C(=O)Nc1ccc(S(N)(=O)=O)cc1Br +COc1cc2nncc(-c3cnc(N4CCC(C(C)(C)O)CC4)c(C(F)F)c3)c2cc1OC +CC1CCCCN1CCCNC(=O)c1ccc2nc(N3CCCCC3)sc2c1 +CCn1nccc1-n1nnc2c1CC(C)N(C(=O)c1cccc(C(F)(F)F)c1Cl)C2 +CN1CCN(c2cccc(Nc3nc4c(NCc5ccccc5CN(C)S(C)(=O)=O)cccn4n3)c2)CC1 +CC12CCC3C(CCC4=CC(O)CCC43C=NO)C1(O)CCC2C1=CC(=O)OC1 +Cn1cc(-c2cc(C(N)=O)nc3cc(CN4CCOC(CC(F)(F)F)C4)ccc23)cn1 +CN1Cc2cc(C(F)(F)F)ccc2Oc2ccc(-c3cccc(C(O)CO)n3)cc21 +c1ccc2oc(CN(CCCCCCCNc3c4c(nc5ccccc35)CCCCC4)Cc3cc4ccccc4o3)cc2c1 +Cc1nn(C2CCN(CC(=O)N(C)C)CC2)c(C)c1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1 +COc1cccc(NC(=O)C=Cc2ccc(C(C)(C)C)cc2)c1 +CN1CCN(c2nccn3c(-c4ccnc(NC(CN)c5cccc(Cl)c5)n4)cnc23)CC1 +O=C(c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)N1CCN(c2ccccn2)CC1 +COc1cccc2c1C(C(=O)NCc1ccc(OC(F)(F)F)cc1)N(CCc1ccccn1)C2=O +CCCSc1nc(Sc2ccccn2)c2nnn(Cc3ccccc3)c2n1 +Cc1c(Sc2ccc(Cl)cc2)c2c(S(C)(=O)=O)cccc2n1CC(=O)O +N#Cc1cncc(N2CCC(S(=O)(=O)c3ccc(N4CCN5CCCC5C4)cc3Cl)C2)n1 +Cc1ccc(NC(=O)c2cncc(N(C)C)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)n1 +CC(C)N1CCC(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)CC1 +Cc1nsc(-c2ccc(N3CCN(c4cccc(Cl)c4)CC3)nn2)n1 +COc1cc2oc(=O)c(OCCCCOc3cc(O)cc(N(C)C)c3)c(C)c2cc1OC +Cc1sc(-c2ccccc2)nc1CCNC(=O)c1c(C(=O)N2CCC2)cnn1C +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)NCc3ccccn3)[nH]c12 +NCCCOc1cc(C(N)=O)c2ncnc(NCc3ccc(C(F)(F)F)cc3)c2c1 +Cc1ccc(C(=O)NC2CC2)cc1Nc1ncnn2cc(C(=O)c3ccc[nH]3)c(C)c12 +COc1ccc(C(=O)Nc2ccc(C)c(-n3cc(-c4cccnc4)cn3)c2)cc1 +O=C(NC1CCN(CCc2ccc(OC3CCNCC3)c([N+](=O)[O-])c2)C1)c1ccc(Cl)c(Cl)c1 +Cc1c(-c2cccc(OCC(=O)O)c2F)c(=O)n(CC(N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F +CCN(CC(O)(CNc1cccc2c1cnn2-c1ccc(F)cc1)C(F)(F)F)C(=O)c1ccccc1C 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+COc1cc(F)c(-c2nc3c(NCC4CCNCC4)c(Cl)cnc3[nH]2)cc1OC +CC(c1ccc(OC(F)(F)F)cc1)N1CCC2(CCC(O)CC2)OC1=O +Nc1ccc(CC(C(=O)O)c2cn(Cc3ccccc3)cn2)cn1 +CC(C)Nc1cc(-n2ccc3cnc(N4CCC(O)C4)nc32)ncc1C(=O)NCC(F)C(C)(C)O +CC(C)CCN1C(C)CCCC1C(=O)NC(Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C +CC(C)NC(=O)c1cccc(-c2cc(-c3ccc(CNC4CCOCC4)cc3)on2)c1 +CC(C)n1nnc(-c2onc(O)c2CC(N)C(=O)O)n1 +CCNCc1cccc(C(=O)Nc2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)c1 +O=C(Nc1ccc(C2CNCCO2)cc1)Nc1ccccc1Cl +COc1cccc(-c2nc(N)c3c(C)c(C)n(C(C)c4ccccc4)c3n2)c1 +CN1CCCC1COc1cnc(Cl)c(C=Cc2ccccn2)c1 +O=C(CCC(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCC(CO)(Cc5ccccc5F)C4)cc23)ccn1 +COc1ccc(Cn2c(N(C)C)nc3cc(-n4cnc5cc(-c6ccc(Cl)cc6)sc5c4=O)ccc32)cc1 +Oc1cc(Nc2cccnc2)cc(-c2cccc3[nH]cc(Cl)c23)c1 +NC(=O)C1CCCN(c2nc(N3C4CCC3COC4)nc3scc(-c4ccccc4Cl)c23)C1 +O=C(COc1ccccc1C1CCCCC1)NCC(O)CN1CCc2ccccc2C1 +COc1ccc(C=C2SC(=Nc3cccc(C(=O)O)c3)N(C)C2=O)cc1 +CCc1sc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)nc1CN(CC)CCO 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+COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 +Cn1cnc2cc(-c3ccc(N4CCC(CO)C4)c(S(C)(=O)=O)c3)nc(NC3CC3)c2c1=O +COCCn1c(-c2ccc(Cl)s2)nn(CC(=O)NCC(NC(=O)OC(C)(C)C)c2ccccc2C(F)(F)F)c1=O +CS(=O)(=O)N(CC(C(=O)NO)N1CCN(c2ccc(Cl)cc2)CC1)c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1 +CC(C)C12OC1C1OC13C1(OC1C(O)C1(O)C4=C(CCC13C)C(=O)OC4)C2O +COC(=O)c1ccc(-c2ccc3c(c2)Nc2ccccc2NC3=O)cc1OC +CC(=O)SCCC(=O)N1C(C(=O)O)CC2CCCCC21 +COc1cccc2c1CCN2Cc1cnc2nc(N)nc(N)c2c1C +CCOc1nc2c(C(=O)NCc3ccccc3C(F)(F)F)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccccc2Cl)CC1 +CN1CCN(c2ccc3[nH]c(-c4ccc5[nH]c(CCCCCCc6ccc(N(CCCl)CCCl)cc6)nc5c4)nc3c2)CC1 +NC(=O)c1c(N2CCN(CCO)CC2)nc2sc3ccccc3n2c1=O +N#Cc1cnc2c(Cl)cc(NCc3cn(Cc4ccccn4)nn3)cc2c1Nc1ccc(F)c(Cl)c1 +CCCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2noc(O)n2)cc1 +OC1(c2cccnc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +Cc1cnc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)s1 +O=C(NCCN1CCNCC1=O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CCOC(=O)c1nn(C(=O)c2ccsc2)c2ccccc12 +CC1CN(C(=O)c2ccc(-c3ccncc3)c(F)c2)CCN1C(=O)c1ccc2cc[nH]c2c1 +COc1ccc(Nc2cc(NC3CCCCC3N)nnc2C(N)=O)nc1OC +Cc1cc(Sc2ccccc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +CSc1cccc(NC(=O)CN2CCC(c3cccc[n+]3[O-])CC2)c1 +CC(NC(=O)C(C)(C)C)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1 +O=C(NCC1(N2CCOCC2)CCCCC1)c1ccc2[nH]nc(-c3ccc(N4C5CCC4COC5)cc3)c2c1 +Cc1nnsc1C1=NNC(=O)C1=Cc1cn(C)c2cccc(OCc3ccccc3F)c12 +CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(C(=O)Nc2ccc(F)cc2)cc1 +S=C(SSC(=S)N1CCOC(COc2ccccc2)C1)N1CCOC(COc2ccccc2)C1 +Nc1ncc(C2CCC(O)CC2)nc1-c1ccc(C(=O)NCc2ccccc2)c(F)c1 +O=c1n(CCc2ccc3ccccc3n2)nc2cccc(N3CCCCC3)n12 +O=C1c2cc(-c3ccnc(NC4CCOCC4)n3)[nH]c2CCN1C(CO)c1ccccc1 +N=C(Nc1ccc(CNCCc2cccc(NC(=N)c3cccs3)c2)cc1)c1cccs1 +COc1cc(NC(=Nc2ccccc2)NC#N)ccc1-c1cnco1 +CCS(=O)(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C(=O)NC +CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)C(=C(C)Nc3ccc(Br)cc3)C(=O)C12C +CNC(=O)C1Cc2cc(F)ccc2N1C(=O)COc1ccc(F)cc1 +Nc1ccn2c(-c3ccncc3)c(-c3ccc(F)cc3)nc2n1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3C)C2)cc1 +CN(C(=O)C1CCc2cc(NS(C)(=O)=O)ccc2O1)C(CN1CCC(O)C1)c1ccccc1 +COc1ccc(-c2ccc(OCc3cc(C(=O)NS(=O)(=O)c4ccccc4)oc3C)cc2)nc1 +O=C(NC1CCN(CCc2ccc(OC3CCNCC3)cc2)C1)c1ccc(Cl)c(Cl)c1 +CCC(C)(C)Nc1cccnc1N(C)C1CCN(C(=O)c2cc3cc(NS(C)(=O)=O)ccc3[nH]2)CC1 +O=C1OC2(CCN(Cc3ccccc3)CC2)c2c(-c3cccc4ccccc34)sc(-c3cccc4ccccc34)c21 +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)c1ccccc1-c1cncnc1 +CCN(C(=O)c1ccc2[nH]c(-c3cc(C)cc(C)c3)c(CCNCCCCc3cccnc3)c2c1)C(C)C +Cc1sc(-c2ccc(C(C)C)cc2)nc1CCOc1ccc2c(c1)CCC2CC(=O)O +CC(C)OC(=O)C(C)NP(=O)(COC(C)Cn1cnc2c(N)ncnc21)Oc1ccccc1 +Nc1ncc2c(n1)-c1c([nH]c3ccc(Cl)cc13)CCC2 +COc1cc(C(=O)NCc2cccc(Cl)c2)ccc1-c1cn[nH]c1 +NC(=O)NC1=C(C(N)=O)C=C(c2ccc(F)cc2)C1 +CN(C)c1cccc2c1CCN(C(=O)C=Cc1cc(Cl)ccc1-n1cnnn1)C2C(=O)Nc1ccc(C(=O)O)cc1 +CCCCCCCNC(=O)C1(C)CC(c2ccc(C)cc2)=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1 +COc1cc(C(=O)Nc2ccc(-c3cccc([N+](=O)[O-])c3)cc2)cc(OC)c1OC +C#Cc1nc(NOC)c2ncn(C3OC(CO)C(O)C3O)c2n1 +O=C(Nc1ccc(N=C2NCCN2)cc1)c1ccc(N=C2NCCN2)cc1F +Cc1c(CC(=O)Nc2ccncc2)c2cc(F)ccc2n1Cc1ccc(F)cc1 +CCN=C1SC(=Cc2cc(C)n(-c3ccc(F)cc3F)c2C)C(=O)N1CC +Cc1cccc(CCNCc2cc3cc(C)cc(C)c3nc2O)c1 +N=C(N)c1ccc2cc(OC(=O)c3ccc(NC4=NCCN4)cc3)ccc2c1 +O=C(c1ccc(N2CCCC2)c(OCC2CC2)n1)N1CC2(COC2)C1 +COc1cccnc1C(C)c1c(CCN(C)C)sc2ccccc12 +CN(C(=O)Cc1cccc2occc12)C1CCCCC1N1CCCCCC1 +NC(=O)Nc1sc(-c2ccc(Cl)cc2)cc1C(=O)NC1CCCNC1 +CS(=O)(=O)c1ccc(-n2cc(C(F)F)nc2-c2ccc(Cl)cc2)cc1 +COc1ccc(N2CCN(CCCC(=O)NC3c4ccccc4C=Cc4ccccc43)CC2)cc1OC +COc1nccc2c1ccc1nc3cccc(C(=O)NC(CO)CN(C)C)c3nc12 +CN(C)C(=O)CN1CCC(CCOc2ccc(-c3cc4c(ncn4C)c(C#N)n3)cc2C(F)(F)F)CC1 +CC(=O)c1cc(Cl)c(C(=O)Nc2ccnc(NC(=O)C3CC3)c2)c(Cl)c1 +CC(C)CC(NC(CCc1ccccc1)C(=O)O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +COc1ccc2[nH]cc(CN3CCCC4(CCN(c5nc(C)cc(C)n5)CC4)C3=O)c2c1 +CCCCNc1ncc(C(=O)NCc2ccc(F)cc2)c(NC2CCC(O)CC2)n1 +CCOC(O)=C1C(COCc2cc(O)nc(C(C)(C)C)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +O=C1c2ccc(Nc3ccc(F)cc3F)cc2CCc2ccc(O)cc21 +CCCCC(NC(=O)OC(C(C)(C)C)C(C)(C)C)C(=O)C(=O)NC(C)c1ccccc1 +CCN(CC)CC#CCN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 +O=C(c1cccnc1)N1CCC(n2ncc3c(N4CCOCC4)nc(-c4ccc5[nH]ccc5c4)nc32)CC1 +O=C(NCCCNCc1ccc2ccccc2c1)c1ccc2nc(NC(=O)C3CCCCC3)sc2c1 +CN(CC(C)(C)O)C(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +COc1ccc(NCc2cnc3nc(N)nc(N)c3c2C)c2ccccc12 +CCc1nccc(-c2ccc(C(=O)N3CCN(CC)CC3)c(F)c2)c1C#Cc1ccc(N)nc1C +CCN(CCNC(=O)c1ccccc1)C(=O)c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +CCCc1nc(C)n2c(O)nnc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCN(CC)C(=O)C1(c2ccccc2)CC1CNCC(O)COc1cccc2[nH]ccc12 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cccc(OCc4ccccc4)c23)C1(C)C +O=C(C=Cc1ccc(Sc2ccc(Cl)cc2Cl)c(Cl)c1)N(CCO)CCO +Cc1[se]c(C=C2C(=O)Nc3cc(-c4cccc(O)c4)ccc32)cc1C(=O)NCCCn1ccnc1 +CCOc1cc2cc(-c3c(C)nc(NCCOC)nc3NC3CC(CO)C(O)C3O)oc2c(C)n1 +NC(=O)c1cc(OCCO)cc2c1-c1ccccc1C2(O)C(F)(F)F +CCCCCCCCCCCCCC(=O)CC(=O)Nc1c(C(C)C)cccc1C(C)C +CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)C(C)(CC(=O)O)CC(c2cncc(Cl)c2)C1c1ccc(Cl)cc1 +C#CC(=O)Nc1cc(-c2cnc3[nH]cc(Cl)c3c2)ccc1F +O=C(O)CC(NC(=O)CCCCc1ccc2c(n1)NCCC2)c1cnc2ccccc2c1 +CSc1nc(-c2cccc(C(F)(F)F)c2)c(-c2ccnc(NC(C)c3ccccc3)c2)[nH]1 +c1cc2c3cnc(Nc4ccc(N5CCNCC5)nn4)nc3n(C3CCOC3)c2cn1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(N3CCN4CCCC4C3)nc12 +COc1ccc(C(=O)Nc2cnccc2Cl)cc1OC1CCCC1 +O=C(Nc1ccon1)c1cc(-c2cccnc2)nc2ccc(Cl)cc12 +O=C1C(NS(=O)(=O)C=Cc2ccc(Cl)s2)CCN1c1ccc(C2CCCN2)cc1F +COc1cc(Nc2c(C#N)cnc3cc(-c4ccsc4CN4CCOCC4)ccc23)c(Cl)cc1Cl +NS(=O)(=O)c1ccc(C(=O)CSc2ncccn2)cc1Cl +Cc1nc(NC(C)c2cccc(-c3ccc(CO)nc3)c2)cc(-c2ccc3ncsc3c2)n1 +O=S(=O)(Nc1ncns1)c1ccc(Oc2cc(C(F)(F)F)nn2-c2ccccc2)c(F)c1 +CCCSc1nc(N2CCCC(Cc3nnn[nH]3)C2)ccc1C(=O)NC1CCCCC1 +Cc1cc(C)n(-c2ccc(C(=O)N3CCC(F)(F)C(=CC(=O)NCc4ccccn4)c4ccccc43)c(Cl)c2)n1 +COC(=O)N1CCC(Oc2ncnc3c2CN(c2cnc(OC)c(C#N)c2)CC3)C1 +O=C(Nc1ccc(OC2CCN(C(=O)C3CCCCO3)C2)cc1)N1Cc2ccncc2C1 +CC(C)C1CN(C(=O)Nc2cccc(F)c2)CCN1C(=NC#N)Nc1cccc2[nH]ncc12 +CCCN(CCC)c1cc(C)nc2c(-c3ncc(O)cc3C)c(C)nn12 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+CN(C)CC1Cn2c(-c3cccc(Cl)c3)c3c(=O)n(C)c(=O)n(C)c3c2C(c2ccc(Cl)o2)O1 +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccncc1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(CCCCCl)Oc1ccccc1-3 +O=C1CCOc2c(OCCNCCCCc3ccc4c(c3)CCO4)cc(F)cc21 +CC(O)(c1ccc(C(=O)N(C2CC2)C2CCC(C#N)(C3CC3)CC2)cc1)C(F)(F)F +CNC(=O)c1ccc(-c2cnc3nnc(Cc4ccc5ncccc5c4)n3n2)cc1F +COc1ccc2c(C=C(C)C(=O)c3cc(OC)c(OC)c(OC)c3)cn(CCO)c2c1 +O=C(O)COc1ccc(Cl)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1Cl +CCOCCC1(Oc2ccc(Oc3ccc(C(=O)NCc4cccc(F)c4)cc3)cc2)C(=O)NC(=O)NC1=O +CCCCC(NC(=O)OCC1(CSc2nccn2-c2ccccc2)CCC1)C(=O)C(=O)NC(C)c1ccccc1 +CC(C)C(C)Nc1cc(-c2[nH]c([S+](C)[O-])nc2-c2ccc(F)cc2)ccn1 +Nc1nc(N)c2cc(C=CC(=O)Oc3ccccc3)ccc2n1 +COC(=O)c1c(C(=O)N2CCC(=O)CC2)cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(Nc3ccc4ccn(C)c4c3)CC2)CC1 +O=C(NO)c1cnc(NC2(c3ccc(F)cc3Cl)CC2)nc1 +O=C(Nc1ccc(C2CCNC2)cc1)OCCc1ccc(Cl)cc1 +Clc1cccc(Cl)c1-c1nc2ccnc(Nc3cc(N4CCOCC4)ncn3)c2[nH]1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(c2cccc(C#N)n2)CC1 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+Cc1cnc(N2CCN(C(=O)C3CCS(=O)(=O)CC3)C(c3ccc(F)cc3)C2)nc1 +CC1(O)C(O)C(COC(=S)NCc2ccccc2)OC1n1cnc2c(NC3CCCC3)ncnc21 +O=c1[nH]c(Oc2cnn(Cc3ccccc3)c2)nc2cnccc12 +O=C(Nc1ccccc1)Nc1nc2ccccc2n2c(=O)c(-c3ccccc3)nn12 +CCC(=O)N(c1ccccc1)C1(COC(C)=O)CCN(CCc2cccs2)CC1 +Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(F)c(F)c4)cc3)cc2n1 +CC(=O)c1ncnc2c(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12 +CCC(O)=C(C#N)C(=O)Nc1ccc(-c2ccc3c(c2)OCCO3)c(C(=O)OC)c1 +COc1cc2c(cc1C(=O)Nc1ccc(O)cc1)CCC1C2(C)CCC(O)C1(C)C +CCCCn1c(Sc2nc3cccc(OC)c3s2)nc2c(N)ncnc21 +CCN(CC)C1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4ccc(O)c(OC)c4)cc23)CC1 +CCc1cccc2c(-c3nsc(CN4CCCC4)n3)cn(CC3CCOCC3)c12 +Cc1cc(NCCNC2CCCC2)n2nc(C)c(-c3c(Cl)cccc3Cl)c2n1 +Cc1cnc(-c2cc(N3CCC(NC(=O)CN(C)C)CC3)ncc2Cl)c(C)c1 +CCC(c1nn2cccc2c(=O)n1Cc1ccccc1)N(CCC(C)(C)N)C(=O)c1ccc(Cl)cc1 +C#Cc1cccc2oc(C(=O)Nc3ccc(-c4ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc4)cc3)c(C)c12 +CN1CCN(C(=O)C(Cc2ccncc2)c2ccccc2)CC1 +O=C(c1cccc(-c2cccc(O)c2F)n1)c1ccc(O)c(O)c1O +Cc1cc(COC2C(O)C3C(C(=O)O)C3C2(N)C(=O)O)ccc1F 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+O=C1c2cc(-c3ccnc(NC4CCC(O)C4)n3)cn2CCCN1C(CO)c1ccccc1 +CCc1nc2cc(F)ccc2n1-c1ccc(C(=O)NC2CC2)s1 +CC(=O)Nc1cccc(C2CCN(CCCNc3nc4ccccc4n3Cc3ccc(C(C)(C)C)cc3)CC2)c1 +Cc1nc(O)c2cc(NCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cn3)ccc2n1 +CC(C)CN(Cc1ccc(NC2(C)CCN(S(C)(=O)=O)CC2)cc1)S(=O)(=O)Cc1ccccc1 +CC(C)CC(NC(=O)Cc1ccc(F)cc1)c1nc(C(=O)NC(CCCNC(=N)N)C(=O)O)co1 +O=C(NCC(c1cnc(C(F)(F)F)nc1)N1CCC(F)CC1)c1ccccc1Cl +CCCOC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1 +CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Br +COc1cc(C(=O)NC2CCN(C)CC2OC)c(F)cc1Nc1ncc(Cl)c(Oc2cccc3c2C(=O)N(OC)C3)n1 +Cc1csc2nc(C(C)NC(=O)C=Cc3ccc(N(C)C)cc3)oc(=O)c12 +NS(=O)(=O)c1nc2ccc(ONC(=O)c3cccc(C(=O)O)n3)cc2s1 +CN1C(=O)C(c2ccc(OC(F)F)cc2)(c2ccc(F)c(OCCF)c2)N=C1N +O=C(CCCCc1cccn1Cc1cccc(-c2ccccc2)c1)NO +CC1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)C(CN2CC(C)OC(C)C2)CN1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(C(F)(F)F)c(F)c4)cn3CCN3CCC3)CC2)c1C1CCC1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(Cl)nccc2n1CC(=O)O 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+O=C(c1cccc(OCC(O)CNC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)c1)N1CCOCC1 +COc1cc(Cl)c(C)cc1NS(=O)(=O)c1ccc(OC)c(N2CCNCC2)c1 +COc1ccc2sc3c(c2c1)N(Cc1ccccc1Cl)CCNC3=O +COCc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +COC(=O)C(CCSSCCC(NCCC(=O)c1cc2ccccc2s1)C(=O)OC)NCCC(=O)c1cc2ccccc2s1 +CC1CCN(C(=O)C2CCN(Cc3ccccc3)C2=O)CC1N(C)c1ncnc2[nH]ccc12 +CNC(=O)C(C)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(C)cc5)cc4)csc23)cn1 +COc1cc(CNC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cc(OC)c1 +NS(=O)(=O)c1ccc(SCc2ccc(C(F)(F)F)cc2)s1 +CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)c3ccccc3)CC2)nc1C +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(CO)(Cc5c(F)cccc5F)C4)cc23)ccn1 +Cc1nn(C)c2nnc(Nc3ccc(S(=O)(=O)N4CCCCC4)cc3)nc12 +CC(=O)Nc1cccc(-c2c(-c3ccc4nccnc4c3)n(C)n(C)c2=O)c1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CCO)cc3)cc2s1)S(=O)(=O)CCC(F)(F)F +COc1cccc(S(=O)(=O)Nc2ccc(NS(=O)(=O)c3cccc(OC)c3)c3ccccc23)c1 +Cc1cc(C)c2sc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3)nc2c1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(S(C)(=O)=O)cc3)CC2)ncc1Br +Fc1ccc(COc2cn3c(-c4ccc(OC(F)F)cc4)nnc3cn2)cc1F +Cc1cccc2cc(C(=O)NCCCCCC(=O)Nc3ccccc3N)[nH]c12 +CCc1cn(C2CC(O)C(CNC(=O)Cc3c(C)cccc3C)O2)c(=O)[nH]c1=O +CC(C)(C)NC(=O)C1CCN(Cc2nccc(NC(=O)c3cccc(C(F)(F)F)n3)n2)CC1 +COc1ccc(-c2nc(Nc3cccc(NC(=O)C4CCNCC4)c3)nc3[nH]cnc23)cc1OC +CC(c1ccc(-c2cccc(S(N)(=O)=O)c2)cc1)C(N)C(=O)N1CCC(F)C1 +CS(=O)(=O)Cn1cnc2c(N3C4CCC3COC4)nc(-c3cnc(N)nc3)cc21 +FC(F)(F)c1ccc2[nH]c(N3CCN(c4ncccc4C(F)(F)F)CC3)nc2c1 +[O-][S+](c1ccc(C(F)(F)F)cc1)c1c(O)c(-c2cccnc2)cc2ccccc12 +COCCCCC(O)(c1ccc(F)cc1-c1cccc(C)c1)C1CCCN(C(=O)C2CC(N)C(O)C2)C1 +O=C(O)c1cc2c(s1)-c1cc(F)c(Cl)cc1OC2 +COc1cc2c(=O)n(CCN3CC4CCc5c(OC)cccc5C4C3)c(=O)n(C)c2cc1OC +O=C(C=Cc1ccc2c(c1)CN(S(=O)(=O)c1ccccc1)C2)NO +COCCNc1cc(NC(=O)N2CCCc3cc(-c4cn(C)nc4C)c(C=O)nc32)ncc1C#N +CCOC(=O)CCCn1c(=O)oc2cc3ncnc(Nc4ccc(OCc5ccc(Cl)cc5)c(Cl)c4)c3cc21 +COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N2CCC(CN3CCN(C)CC3)CC2)c(C)c1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccccc1OCc1cccs1 +Cc1cc(-c2cnc3c(NCCC(F)(F)F)cc(C(F)(F)c4cccc(F)c4)nn23)ccc1C(=O)NC1CC1 +Cc1cc(C(=O)N(C)C)cc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Br)c(C)c3)CC2)n1 +CC(CCc1ccccc1)NCC(O)c1cc(C(N)=O)c2[nH]ccc2c1 +Cc1ccc(Oc2ccc(C(=O)NCCN3CCCC3)cc2NC(=O)C2CC2c2ccccc2)cc1C +COc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCCCC4)cc3)cc12 +OC1(c2ccc(Cl)cc2)CC2CCC(C1)N2CCCSc1ccc(F)cc1 +N#Cc1ccc(Cn2cncc2CNC2CCN(C(=O)c3cccc4ccccc34)C2=O)cc1 +Cc1ccc(OCC(C)(C)O)cc1-c1nnc2c(C)nc3ccc(C(C)C)nc3n12 +O=C(Cc1cccc(Cl)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)nn1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2c(-c3ccncc3)cccc21 +C=Cc1ccc(CN(C(Cc2cccs2)C(=O)NO)S(=O)(=O)c2ccc(OC)cc2)cc1 +CCCn1c(-c2ccccc2)cc(C(=O)NCCCN2CCN(c3cccc4cccnc34)CC2)c1C +COCCNC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2ccccc2)cc1 +O=C(NC=Cc1ccccc1)C(c1csc2ccc(Cl)cc12)P(=O)(O)O +COc1cc(-c2nnc3n2CCCC32C(=O)N(CC(F)(F)F)c3ccccc32)ccc1-c1cnc(C)o1 +CC(C)(NC(=O)c1ccc(C2CC2)c(OCC(F)(F)F)n1)c1nccs1 +CCN(c1cc(Cl)cc(C(=O)NCc2c(C)cc(C)n(C)c2=O)c1C)C1CCC(N(C)C)CC1 +CCN(c1nc(C)cc(C)n1)c1ccc(C(C)C)cc1Br +CCn1nc(C2CCN(CC3CN(C(C(=O)O)C4CCCCC4)CC3c3ccccc3)CC2)cc1Cc1ccccc1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NS(=O)(=O)CCN3CCOCC3)no2)cc1C#N +CC(C)(C)C1(c2ccccc2)OCCC(CCNCc2ccccc2)O1 +O=C(c1ccccc1)N1CCC(n2cnc3cnc4[nH]ccc4c32)CC1 +CC12CCOCC1C1(COC(N)=N1)c1cc(-c3cncc(Cl)c3)c(F)cc1O2 +Cn1c(=O)c2c(nc3n2CCCC(=O)N3CCCN2CCN(c3ncccn3)CC2)n(C)c1=O +CCOc1ccc(-n2c(C)c3c(C)nnc(-c4cccc(OC)c4)c3c2C)cc1 +NC(=O)c1cc(CNCCN2CCNC2=O)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +COc1ccc(-c2cnc(Nc3ccc(C4CNCCO4)cc3)nc2)cc1OC +Cc1cn2cc(C(F)(F)F)cc2c(C#Cc2cccc(F)c2)n1 +CN1CCN(C(=O)CNc2c(C(=O)C3CC3)cnc3ccc(-c4ccc(O)c(Cl)c4)cc23)CC1 +COc1ccccc1N1CCN(CCCCNC(=O)C(C)(C)C)CC1 +O=C1C2C3C=CC(C3)C2C(=O)N1c1ccc(F)c(Cl)c1 +Nc1nc(OC2CCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CCCc1c(C#N)cn(-c2ccc(C(=O)O)cc2)c1C +COCc1cc(-c2ccc3c(c2)C2(N=C(C)C(N)=N2)C2(CCC(OC)CC2)C3)cc(C#N)c1F +COc1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)N(C)CC(C)C)CC3)c2)c1 +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2NC2CCCC2)C1 +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(Cl)cn3)CC2)CC1c1ccc(F)c(Cl)c1 +CCC(c1ccc(-c2cccc(OC)c2)cc1)n1ccnc1 +Cn1c2c(c3ccc(-n4ccc(OCc5ncc(Cl)cc5Cl)cc4=O)cc31)CCNCC2 +Cc1nnc(C(C)C)n1C1CCN(C(C)CC(NC(=O)C2CC(F)(F)C2)c2ccccc2)CC1 +CCOCCCNC(=O)c1cc(NC(=O)Nc2cccc(Cl)c2)ccc1N(C)C +CCOC(=O)c1cc2cc3c(cc2nc1NC(=O)Nc1ccc(Br)cc1)OCO3 +O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)N1CCC(c2cccs2)CC1 +CC(C)c1csc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)n1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccncc3)nc2n1 +CC1=C(CNS(C)(=O)=O)C2=C(C)C3(CC3)C(C)(O)C(=O)C2=C1 +COc1ccc(-c2cc3c(NC(C)c4ccccc4F)ncnc3o2)cc1 +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCC(CCC(=O)NO)CC4)ccc3OCC)nc12 +COc1cc2c(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)ncnc2cc1C +CCCCN(CC)c1nc(C)nc(N(CC)c2ccc(C(C)C)cc2Br)n1 +O=C(C=Cc1cc(C(=O)c2ccc(F)cc2)cn1-c1ccccc1)C=C(O)C(=O)O +CN(C)CC=CC(=O)Nc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2cn1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(Cl)cc1CN1CCC(F)(F)CC1 +COC(O)=C1C(C)=NC(C)=C(C(=O)OCCSc2ccccc2)C1C +Cc1cc(F)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(C=CC(=O)O)cc1 +O=C(NC1CCN(Cc2ccccc2)CC1)c1cc2nc(-c3ccc(Cl)s3)cc(C(F)(F)F)n2n1 +COCC1(CNc2nc(C)c(-c3nc4c(C)nccc4s3)c(NC3CC(C(C)(C)O)C(O)C3O)n2)CC1 +CC(C)(C)OC(=O)N1CCC(C(=O)NS(=O)(=O)c2c(Cl)sc(Cl)c2Br)CC1 +COc1ccc(C(=O)Nc2sc(Nc3ccc4ncccc4c3)nc2C(N)=O)cc1 +CSCCC(NC(=O)c1ccc(NCc2cccnc2)cc1-c1ccccc1C)C(=O)O +Cc1cc(C)c(-n2cc[n+](CC(=O)c3ccc4ccccc4c3)c2)c(C)c1 +NC(=O)N1CCCc2cc(-c3cncc(OCc4cccnn4)c3)cnc21 +CC(C)(Cc1ccccn1)N1C(=O)c2ccccc2C1C(=O)NCc1ccc(OC(F)(F)F)cc1 +CCC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)CC1 +Cc1cc(C(=O)Nc2cncc(C(=O)c3cn(C(C)C)c4ncncc34)c2)nn1C +O=C(O)C(Cc1ccc(OCc2ccccc2)cc1)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Cc1ccc(N(CCN2CCC(OCC(=O)O)CC2)C(=O)c2ccc(Cl)cc2)cc1 +O=C(NCc1cccc(-c2nn[nH]n2)c1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 +CCC(CC)C(=O)Nc1ccc(-c2nnc(-c3ccc(OC)cc3)o2)cc1 +Cc1cc2c(NC(=O)NC3CCC(c4nc(C)cs4)C3)c(F)ccc2cn1 +C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(S(C)(=O)=O)ccc3n2Cc2cccc(C(=N)N)c2)cc1 +COc1cc(OC)cc(N(Cc2cn(CCO)nn2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +N#Cc1cc(-c2ccnc(Nc3ccc(NC(=O)CC4CCC(O)C4)nc3)n2)cnc1N1CCC(F)C1 +c1cnc2[nH]cc(-c3ccnc(N4CCCC4)n3)c2c1 +CCOc1nc2cc(Br)ccc2c2[nH]c(-c3ccccc3Cl)nc12 +COC(=O)c1c(NC(=O)CSc2cccc(OC)c2)cnn1CCc1ccccc1 +CNc1nc(Nc2cn(C(C)(C)CC#N)nc2C)ncc1C(F)(F)F +O=C(CO)N1CCC(c2n[nH]c(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1 +CC(C)=CCc1cc(C(=O)Nc2cc3ccc(OCCCN(C)C)c(C)c3oc2=O)ccc1O +COc1ccc2ccccc2c1C1CC(Cl)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +O=C(O)C1CCN(c2cc3cccnc3c(-c3cccc(F)c3)n2)CC1 +Cn1cc(O)c(=O)cc1CNCCNc1ccnc2cc(Cl)ccc12 +Cn1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC(O)C3)n2)cn1 +O=C(C(=O)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])c1ccccc1 +Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1Cl +N=C(N)c1ccc(O)c(CN2CCC(NS(=O)(=O)c3cc4ccncc4s3)C2=O)c1 +CCc1c(C)[nH]c2c(-c3cnn(-c4cc(CO)ccn4)c3)cnn2c1=O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc(N)ccc1c2[Si](C)(C)C +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(F)cc1)C(=O)C(C)Cl +O=C(O)C(O)C1CCCN1CCC=C(c1ccccc1)c1ccccc1 +Cc1nn(CC(F)(F)CCO)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2 +O=C1Cc2cc(N3CCCCC3)c(NC(=O)c3cnn4cccnc34)cc2N1 +CCOc1cc2c3c(c4ccc(O)cc4c2cc1OCC)CC1CCCN1C3 +CC(C)(NC1CCC(C(=O)N2CCN(c3ccc(Cl)cn3)CC2)C(c2ccsc2)C1)c1ccc(Cl)cc1 +CNC(=O)c1ccccc1Sc1ccccc1[N+](=O)[O-] +CN1CC2CC1CN2Cc1nc2c(oc3ccc(Br)cc32)c(=O)[nH]1 +NS(=O)(=O)c1ccc2nc(-n3cc(C(=O)O)c(-c4ccc(F)cc4)n3)sc2c1 +Cc1ccc(OC(=O)c2cccc([N+](=O)[O-])c2)c(-n2nc3ccccc3n2)c1 +CC(C)Oc1ccc2c3c1OC1C(=O)CCC4(NC(=O)C=Cc5ccc(Cl)cc5)C(C2)N(CC2CC2)CCC314 +O=C(Nc1cc2ccc(-c3ccccc3Cl)nc2cn1)C1CC1 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3ccc(N)c(OCC(F)(F)F)c3)C2O)c1 +NC(=O)Nc1sc(-c2ccc(Cl)c(Cl)c2)cc1C(=O)NC1CCCNC1 +CCC(CC)(C(=O)O)c1ccc2c(c1)OCC(Cc1ccccc1)C2O +CCc1c(CC(N)=O)c2cc(OCCCC(=O)O)ccc2n1Cc1ccccc1 +O=C(c1nn(C2CCCN(CCC3CCOCC3)C2)c2c1CS(=O)(=O)c1c(F)cccc1-2)N1CCOCC1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2Cc1ccccc1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)C(F)(F)F)c12 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCC(F)(F)C2)c(-c2cncnc2)c1 +Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2C)c1C +Cc1cc(NCc2ccccn2)c2nc(N3CCOCC3)cc(=O)n2c1 +C=CCCCON=C1C(=O)N(Cc2nc3ccccc3n2CCCOC)c2ccccc21 +CC(=O)NC1CCC(C(C)C(N)C(=O)N2CCC(F)C2)CC1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CN2CCCC2)cn1 +Oc1cc(O)n2ncc(-c3ccc4c(c3)OCO4)c2n1 +O=C(NO)c1ccc(-c2ccc(CN3CCc4ccccc4C3)cn2)s1 +Cc1ccc(S(=O)(=O)OCCC2OC3(CCN(Cc4ccccc4)CC3)c3ccccc32)cc1 +CCCCNC(=O)C(C)CC(O)C(N)CC(C)(C)CCc1cccc2ccccc12 +CCCCc1nc(Cl)c(CNC(=O)OCC)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cc1ccc(CNCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(O)CCc2ccccc2)c(C)c1 +N#Cc1nc(C(=O)NCC(=O)O)c(O)c2ccn(Cc3ccccc3)c(=O)c12 +c1cc[n+](CCCCCCCCCC[n+]2cccc3ccccc32)cc1 +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2cc(Br)ccc21 +CC(Nc1nc2c(S(=O)(=O)c3ccc(Cl)cc3)nnn2c2ccsc12)c1ccccc1 +CCn1nnnc1Cc1ccc2[nH]cc(CCN(C)C)c2c1 +CCCCC(=O)NCc1ccc2c(cnn2-c2ccc(F)cc2)c1 +O=C(NCCc1cccc(Cl)c1Cl)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +COc1ccc(CC(=O)O)cc1-c1noc(-c2ccccc2)c1C(=O)NCCOc1ccc(Cl)cc1Cl +Cc1ccc2c(n1)CCN(c1ncnn3c(C)nc(C4CCOC4)c13)C2 +Cc1cc(NCCN2CCOCC2)c2ccc3ccccc3c2n1 +O=C(c1ccc(Oc2ncccc2C2CCCCO2)cc1)c1nc2ccccc2[nH]1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2ccc(C(C)C)s2)CCCCC1 +CC(NC(=O)Nc1cc2[nH]nc(Nc3ccc(F)cc3)c2cn1)c1ccccc1 +CC(C)(N)c1ccc(-c2nc(Nc3ccc(OCCN4CCOCC4)cc3)ncc2C#N)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1NC1CCC(NC(=O)C2CC2)CC1 +Cc1cc(N2CCN(C3CNC(C(=O)N4CCSC4)C3)CC2)n(-c2ccccc2F)n1 +CN1CCN(c2ncn(-c3ccc(Nc4nccc(-c5cc(F)cc(N6CCOCC6)c5)n4)cc3)n2)CC1 +N#Cc1nc(-c2ccnc(Nc3ccc(NC(=O)CN4CCOCC4)nc3)n2)ccc1N1CCC2(COC2)C1 +CC(=O)Nc1ccc2c(c1)N(C)C(=O)C(NC(=O)c1cc(Cc3ccccc3)on1)CO2 +CC(CN)c1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1F +NC(=O)N1CCCc2c1ncc(-c1cncc(CN3CCOCC3=O)c1)c2F +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CN(S(=O)(=O)c2ccccc2)C1 +CCc1cc(-c2noc(-c3ccc(C)c(CN(C)CC)c3)n2)cc(C)c1OCC(O)CNC(=O)CO +COCCN(C)c1cc(-c2c(C)cccc2C)nc2c1CN(c1cc(C(C)C)ccc1C)CC2 +O=C(Nc1cnn(Cc2cccc(Cl)c2)c1)c1n[nH]c2ccccc12 +CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)c2ccccc21 +CNc1nccc(-c2cnc3c(NC4CCNCC4)nccn23)n1 +COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(-c3c(C)noc3C)c12 +c1ccc(OCCCN2CCc3[nH]c4ccccc4c3C2)cc1 +O=C(NC1CC1)c1ccc(Cl)c(Oc2nncc3c2cnn3-c2ccc(F)cc2F)c1 +COc1ccc(Cc2cc(C3OC4(COC4)C(O)C(O)C3O)ccc2Cl)cc1 +O=C(Nc1cc(-c2ccc3cccnc3c2)ccn1)C1CC1 +COc1ccc(-c2nc3cnc(NCc4ccc(Cl)c(F)c4)nc3n(CCNC(C)=O)c2=O)cc1 +COC1OC2(c3ccc(CO)cc3)CCC3CCCCC31OO2 +CN1CCN(CCN=C(N)c2c(O)nsc2Nc2ccc(Oc3cc(Cl)ccc3Cl)cc2)CC1 +COc1cc2c(cc1O)ncc1c2c(-c2ccc(C#N)cc2)nn1C +O=C(Nc1ccc(OC(F)(F)C(F)F)cc1)c1cnc(N2CCC(O)C2)c(-c2cncc(F)c2)c1 +CCCC1(CCc2ccccc2)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)=C(O)O1 +COc1ccccc1-c1ccc(CC(NC(=O)C2(S(=O)(=O)C3CCCC3)CCCC2)C(=O)O)cc1 +CCN(CC)CCNc1cc(Nc2cc(C(C)C)[nH]n2)nc(NCc2cc(-c3ccccc3)no2)n1 +CCCn1c(=O)c2nc(NC(=O)c3ccc(S(=O)(=O)F)cc3)[nH]c2n(CCC)c1=O +Cc1cnc(COc2ccc3nc(C4CCCCC4C(=O)O)n(Cc4ccc(Br)cc4)c3c2)c(F)c1 +CCOC(=O)C(O)=CC(=O)c1cn(Cc2ccc(F)cc2F)c2ccccc2c1=O +COc1cc(C(=O)NN2c3ccc(Cl)cc3N=C(N3CCN(C)CC3)c3cc(Cl)ccc32)cc(OC)c1OC +NC(=O)c1nn(-c2ccc(S(N)(=O)=O)cc2)c2c1CCc1cnc(NC3CCCC3)nc1-2 +CC(C)(C)COc1cc(C(C)(C)C)ccc1CN=C(S)NCc1ccc(NS(C)(=O)=O)c(F)c1 +CCN(CC)c1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 +Cc1cccc(CC(=O)Nc2n[nH]c3ccc(N4CCCS4(=O)=O)cc23)c1 +COc1ccc(-c2nc(-c3ccnc(C)c3)c3n2CC(C)OCC3)cc1OC(F)(F)F +N#Cc1ccc(C(=O)N2CCN(c3ccc(OCCCN4CCCCCC4)cc3)C(=O)C2)cc1 +Cn1c2c(c3ccccc31)CN(CCCOCc1ccccc1)CC2 +COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1C#CCCCc1ccccc1 +O=C1NC(=O)C2(CCC(=O)N2c2ccc(Oc3ccc(F)cc3)nc2)C(=O)N1 +CC(C)Nc1ccc(Nc2ccnc3cc4ccccc4cc23)cc1 +NC1(c2ccc(-c3nc4c5cc(-c6ccn[nH]6)ccc5nn4cc3-c3ccccc3)cc2)CCC1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4cccc(F)c4F)nc23)N1 +Cc1cc(C(=O)N(Cc2ccccc2)c2ccc(-c3nc(Cl)ncc3C)cc2)c(O)cc1O +CN(C)C(=O)N1CC=C(c2cc3c(-c4cccc(NC(=O)c5ccc(C6CC6)cc5)c4CO)ncnc3[nH]2)CC1 +COC1CCC2(CC1)Cc1ccc(C#N)cc1C21N=C(N)N(CCc2nccs2)C1=O +O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCO)CC1 +COc1ccc2c(c1)C(=O)C(c1ccc(OC)c(C)c1)=[N+]2[O-] +NS(=O)(=O)c1c(F)c(F)c(SCc2ccccc2)c(F)c1F +Cn1cc(C2(c3cnn(C)c3)NC(c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 +COc1ccc(CC(=O)NC(Cc2c[nH]c3ccccc23)CN(Cc2ccccc2OC)C(C)=O)cc1 +CSc1nccc(-c2c(-c3ccccc3)nc3nc(N)ccn23)n1 +Cc1cc(NC(=O)c2nn(C)c(-c3ccc(F)cc3)c2C)ccn1 +CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OCCCC(=O)NO)cc1 +Fc1ccc(-c2[nH]c(SCc3ccccc3)nc2-c2ccnc(NCc3ccccc3)c2)cc1 +O=C(NCc1ccc(N2C3CCCC2CC3)c(F)c1)Nc1cccc2[nH]ncc12 +CON=Cc1c(N)ncnc1Oc1ccc(NC(=O)NCCN(C)C)c(Cl)c1 +CC(CN(C)C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1F +O=C1CN=C(n2cnc(C3CC3)c2)C=C2c3cccc(-c4ccno4)c3CCN12 +COc1cc(Nc2c(C(N)=O)cnc3c(Cl)cc(S(C)(=O)=O)cc23)ccc1F +CN(c1ccc(-c2ccncc2)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +COc1ccc2[nH]cc(C(=O)c3cc(OC)c(OC)c(OC)c3)c2c1 +NC(=O)c1cccc2c(NC(Cn3ccnc3)c3ccccc3)ncnc12 +CC(=O)NCCc1ccccc1-c1onc(C2CNCCC2(O)c2ccc(F)c(F)c2)c1Cl 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+O=C(Nc1cccnc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +COc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1OC +Cc1nc2ccccn2c1-c1csc(Nc2ccc(O)cc2)n1 +O=C1CCc2ccc(OCCCCN3CCN(c4cccc5c4OCCO5)CC3)nc2N1 +CC(=O)N1C2C=C(CN3CCC(NC(=O)Nc4cc(F)cc(OC(C)C)c4)CC3)CC1CCC2 +COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(Cl)cc1 +O=C1OC(c2ccc(O)c(Br)c2)(c2ccc(O)c(Br)c2)c2cccc3cccc1c23 +c1ccc(CNc2ncccc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)nc1 +CC1OC(n2cc(C(=N)S)c3c(N)ncnc32)C(O)C1O +O=C(NO)c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)s1 +CC(=O)N1CCc2c(c(Nc3cccc(-c4ccncc4)c3)nn2CC2CC2)C1 +Cc1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)NCCCC(=O)O)sc2ccccc12 +O=C1c2cccc3cc4ccccc4c(c23)C(=O)N1CCNCCO +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(-c5ccc(C)nc5)ccn34)c12 +COc1ccc(-c2ccnc3cc(-c4cccc(Cl)c4)nn23)cc1OC1CCCC1 +Cc1ccc(C(C)Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)nc1 +O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(N1CCC(F)(F)CC1)c1ccccc1S2 +Cc1cc(C(=O)NC(CCC(=O)O)C(=O)O)sc1CCCSc1c(N)nc(N)nc1O 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+CCN(CCCCCCNC1=CC(=O)C(NCCCCCCN(CC)Cc2ccccc2)=CC1=O)Cc1ccccc1 +O=C(CC(F)(F)F)NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1 +Clc1ccc(-c2ccc(-c3cc(-c4nnn[nH]4)nn3-c3cccnc3)cc2)c(Cl)c1 +CCCCn1c(=O)c2cc3nc[nH]c3cc2n(CCCC)c1=O +CCNc1nc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2C)cc(N2CCOCC2)n1 +CCc1nc2cc(CN3CCC(NC(=O)c4cc(=O)c5ccc(F)cc5o4)CC3)ccc2o1 +CNC(=O)C(NC(=O)C(CC(C)C)C(Sc1ccccc1)C(=O)NO)C(C)(C)C +COc1ccc(S(=O)(=O)c2ccc(C)nc2Nc2c(C)cc(C)cc2C)cc1 +C=CC(=O)Nc1cc2c(Nc3ccc(F)cc3F)ncnc2cc1OCCNC(=O)CN(C)C +Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)CCCCC4CCSS4)ccc3n(C)c12 +O=C(c1ccc(F)c(O)c1)c1cccc(N2CCCCC2)n1 +CCn1cc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cn1 +COC(=O)N1CC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +O=C(CN1CCOCC1)N1CCc2nc(-c3cc4ccccc4[nH]c3=O)[nH]c2C1 +CNC(=O)c1ccccc1Nc1nc(Nc2ccc(NS(=O)(=O)c3ccc(F)cc3)c(OC)c2)ncc1Cl +COCCC1(c2nc(NC(=O)c3ncc(C#N)cc3C)ccc2F)N=C(N)OCC1(F)F +CCOC(=O)c1cc(-c2cc(O)c(Sc3ccccc3C(C)C)c(=O)o2)ccc1O +CC(O)CN(C)c1nc2cc(-c3ccccc3)nnc2c2ccccc12 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+O=C(Nc1ccc(F)cc1)NC1C(=O)N(CCN2CCOCC2)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1cccc(F)c1F)NCC3 +CCc1cc(Nc2nc3ncn(CCCCCOC)c3c(=O)[nH]2)ccc1C +CCCn1c(=O)c2nc(C3CCCC3)[nH]c2n(CCc2ccc(NC(=O)C(C)C)cc2)c1=O +COc1ccccc1C(C#N)NC(=O)C1CCCCC1C(=O)N1CCN(Cc2ccc(F)cc2)CC1 +CC1CCC(C(=O)Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)CN1 +O=C(NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1)c1ccc(-c2ccccc2)cc1 +CCc1ccc(-c2ccc(C(=O)N(C)C3CCN(C(=O)N(C)C4CCN(C)C4)C3)s2)cc1 +O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccccc1 +N#Cc1ccc(-c2ccc(CC(N)C(=O)N3CCSC3)cc2)cc1 +Oc1ncccc1C(C#CC1CC1)(OCc1ccccc1)C(F)(F)F +COC(=O)CN1CCN(C(=O)CNC(=O)c2ccc(C(=N)N)cc2)C(CC(=O)O)C1=O +Nc1ncc(-c2ccccc2)cc1-c1nc2ccccc2[nH]1 +CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C[N+](=O)[O-])CCC43O)C2)C(O)C(O)C1O +Cc1ccc(S(=O)(=O)N2CC3(CC2C(=O)NO)SCCS3)cc1 +CC(C)(C)NCC(=O)Nc1cc(CO)cc(Nc2ccnc3cc(Cl)ccc23)c1 +CC(C)n1c2cnccc2c2cnc(Nc3ccc(N4CCC(N(C)C)CC4)nn3)nc21 +N#Cc1c(N2CCN(c3ncccn3)CC2)ccn2c(CC(F)(F)F)cnc12 +O=C(C1CC(N2CCN(c3noc4ccccc34)CC2)CN1)N1CCC(F)(F)C1 +CCCC1(O)CCN(C(=O)CC2(C3CCCC(CC)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1 +O=C1OCc2c1cc1ccc3c(c1c2-c1ccc2c(c1)OCO2)OCO3 +Cc1nnc(C(C)C)n1C1CC2CCC(C1)N2CCC(C)(CNS(=O)(=O)c1ccccc1)c1ccccc1 +CCCS(=O)(=O)Nc1cccc(-c2[nH]c(C(C)(C)C)nc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +Cn1cc(-c2ccc(-c3cnc(N)c4ccc(C(=O)NC5CC5)cc34)cc2)cn1 +Cc1ccc(Cl)cc1-n1cc(-c2ccnc(N)n2)cc1C(N)=O +Cc1nc(C)c(-c2ccc3c(c2)CCC32CCC(C(=O)O)CC2)nc1C(N)=O +CN(C)c1ccc(C=CC(=O)c2ccc(F)cc2)cc1 +C=C1CCCC2C1(C)CCC(C)C2(C)CC=C1C(OC(C)=O)OC(OC(C)=O)C1OC(C)=O +CC(C)n1cc2c3c(cccc31)C1=CC(CO)CN(C)C1C2 +CCOC(=O)c1c(Nc2cccc(Cl)c2)[nH]c2ccc(O)cc12 +CC1CCC(NCc2ccc3c(c2)Cc2c(-c4ccc(F)cc4)n[nH]c2-3)CC1 +COCC(NC(=O)C(NC(=O)C(CCCc1ccccc1)CC(=O)NO)C(C)(C)C)c1ccccc1 +O=C(Nc1ccc2c(cnn2CCN2CCCC2)c1)NC1CCN(Cc2ccccc2)CC1 +O=C(C1CC(Oc2cccc(F)c2)CN1C(=O)C1CC1)N1CCCN(C2CCC2)CC1 +O=C1CC(c2ccccc2)CN1c1cccc(N2CCNCC2)n1 +CCC(O)(c1cccc(F)c1)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1 +CC(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc3[nH]ccc3c2)c(F)c1 +Cn1c(=O)c2c(nc(OCc3ccccc3)n2C)n(C)c1=O +CC(C)N1CCC(N(C)C(=O)Cn2c(-c3ccccc3)c(C3CCCCC3)c3sc(C(=O)O)cc32)C1 +CNC(=O)c1cc(I)cc(C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl +O=C(NC1CCCC1NC(=O)c1cc2ccc(Cl)cc2s1)c1ccc(-n2ccccc2=O)cc1 +NC1=NC(CF)(c2cc(NC(=O)c3ccc(Br)cn3)ccc2Cl)C2CC2O1 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3S(C)(=O)=O)c1C +O=c1[nH]c2cc(CNS(=O)(=O)c3ccc4ccccc4c3)ccc2n1-c1cc(Cl)c(O)cc1O +CC1CN(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)CCO1 +O=C1Nc2ccccc2C1=C1Nc2ccc(C(=O)O)cc2C1=NO +Nc1ccnc2sc(S(=O)(=O)c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c12 +CN1CCN(C(=O)N(C)c2ccc(NC(=O)c3ccc(C#N)o3)c(N3CCCCC3)c2)CC1 +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)c1F +OCCCNc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1Cl +CCc1ncnc(-c2cc(Cl)c(C(=O)N3CCN(CC(C)(C)O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +c1ccc(CN2CCC3(CC2)OCCc2c3csc2-c2ccccc2)cc1 +Cc1ccc(O)c(Cn2c(NC3CCN(CCN)CC3)nc3c(C)cccc32)n1 +O=C1c2ccc(O)cc2C23CCCCC2C1N(CCCF)CC3 +CCOC(=O)C1=C(C)Nc2nc3c(c(N)c2C1c1ccc(OC)c(OC)c1)CCCC3 +CN(C)C1CCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(NCc2cccc(C(F)(F)F)c2)C1 +CC(=O)c1cc2ccc(OS(=O)(=O)C(F)(F)F)cc2oc1=O +CC(=O)Oc1ccc2c(c1)C1c3cc(OC(C)=O)ccc3C(C2)N(C)C1C +Cc1[nH]cnc1CCNC(=O)CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1=O +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)NO)c1 +COc1ccc2occ(C(=O)Nc3ccc(Cl)cc3)c(=O)c2c1 +O=C(N1CCCC2(CCc3ccccc32)C1)C1(c2ccc(Cl)cc2)CC1 +CC(C)(C)NCCOc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +Cc1c(N(Cc2ccc(OCC3CC3)c(F)c2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +Cn1c(=O)c2c(CCC(=O)Nc3ccccc3C(=O)O)nnn2c2ccc(O)cc21 +CCC(=O)Nc1ccc2c(c1)N(Cc1cc(F)cc3c1OCOC3)C(=O)C2=NO +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5nonc5c4)c3c2)C1 +CS(=O)(=O)N1CC2(CCN(C(=O)Nc3ccc(-n4nccn4)cc3)CC2)c2ccccc21 +Cn1cc(S(=O)(=O)C2CCC(CNC(=O)c3ccc(Cl)cc3Cl)(CC3CC3)CC2)nn1 +CCCn1c(=O)[nH]c2nc(-c3cnn(Cc4cc(-c5ccc(Cl)cc5)on4)c3)[nH]c2c1=O +O=C1N(Cc2cccc(O)c2)C(CCc2ccccc2)C(O)C(Cc2ccccc2)N1Cc1cccc(O)c1 +O=C(CN1CCCCC1)N1CCC(CNc2nc3c(s2)CCCc2ccccc2-3)CC1 +OC(CNc1nc2ccccc2[nH]1)CON=C(C1CC1)C1CC1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5CCC(C4)C5O)cn3)nc2n1C1CCCC1 +CCOC(O)=C1C(COCCn2ccnn2)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +CCCCCn1cc(C(=O)Nc2cccc(C(F)(F)F)c2)c(=O)cc1-c1ccccc1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(Nc3ccccc3)nc(-c3ccccc3)n2)CC1 +CCCCCCOc1cccc(OCCCCNC(=O)NC(CC(=O)[O-])C[P+](C)(C)C)c1 +COc1ccc(NC(=O)c2ccc(NS(=O)(=O)c3ccc4c5c(cccc35)C(=O)N4)cc2)cc1 +Cc1ccc(-c2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)c(N)c1 +CC(C)CC(NC(=O)C(N)Cc1ccccc1F)B(O)O +O=C(NCC1CCc2cc(Br)cc3[nH]c(=O)c(=O)n1c23)c1ccccc1 +O=c1[nH]c2ccccc2c(=O)n1CCN1CCC(Cc2ccccc2)CC1 +COc1cc(C=CC(=O)OCCCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)ccc1O +CCCCOC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +CN(c1ncnc2[nH]ccc12)C1CC(NS(=O)(=O)CCCC#N)C1 +CCCCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(F)c4)c3)nc2n(C)c1=O +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)c(Cl)c3)nc(C(C)O)c12 +CC=C1C2C=C(C)CC1(N=Cc1ccc(O)c(OCC)c1)c1ccc(=O)[nH]c1C2 +COCCOC(=O)N1CCC2C(CC3C(=O)OC(C)C3C2C=Cc2ccc(-c3cccc(F)c3)cn2)C1 +COc1cc2nccc(Oc3ccc(-c4cnc(Nc5cccc(F)c5)n(C)c4=O)cc3F)c2cc1OC +Cc1cccc(C)c1NC(=O)CSCC1CCCN2CCCCC12 +N#Cc1ccc(OCCCN2CCC(C(O)(c3cccc(F)c3)C3CCCC3)CC2)cc1 +CCNC(=O)c1ccccc1C1CC2CCC(C1)N2C(=O)C(CCCc1ccccc1)NC(=O)C(C)(C)N +O=C(O)C=Cc1ccccc1C=CCc1ccccc1Oc1ccccc1 +Cc1ccc(-c2csc3ncnc(SCCC(=O)O)c23)cc1C +CC(OC1CN(C2=CC(=O)CC2)CC1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +NCCCCN(Cc1nccc2c3ccccc3n(CC(=O)N3CCC(O)CC3)c12)C1CCCc2cccnc21 +CC12CCC3c4ccc(OS(N)(=O)=O)cc4CCC3C1CCC2(O)Cc1ccc(O)cc1 +O=C(NN=Cc1cc(Br)c(O)c(Br)c1)c1cc2c(ccc3ccccc32)o1 +CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCC3CCNCC3)c2n1 +CC(C)(COc1cccc2ccc(-c3nnc4ccccn34)nc12)C(O)CO +CC(CC(N)=O)(NC(=O)c1cc(OCC(F)(F)F)c(N2CC(F)(F)C2)cn1)C1CC1 +C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OCCOC +CC1(c2cccc(NC(=O)c3ccc(Cl)cn3)c2)N=C(N)Cn2nccc21 +COc1cc2c(cc1F)N(Cc1ccccc1)CC(C)N(C(=O)Nc1cccnc1)C2C +COc1ccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cc1C +O=C(NCC1(c2ccc(F)cc2)CCC1)C1CCN(Cc2ccccc2)CC1 +Cn1cnc2cc(-c3ccc(S(C)(=O)=O)cc3)nc(NC3CCC3)c2c1=O +COC(=O)CC(c1ccc(OC)nc1)N(C)C(=O)CCCCc1nc2c(cc1Br)CCCN2 +CCN(CC)C(=O)N1CCC(CCC(=O)Nc2ccc(F)c(F)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +CCOC(=O)CCCCON=C(c1cccnc1)c1ccccc1C(=O)N1CCN(C(=O)C2CSC(c3cccnc3)N2)CC1 +CCOc1ccc(C(=O)N2CCN3C(=O)c4ccccc4C23c2ccc(Cl)cc2)cc1 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(C)CC4)ncn3)c2c1 +COc1cc(-c2cc(F)cnc2OC)c(F)cc1-c1nccc2cc(S(=O)(=O)Nc3ccon3)ccc12 +CC(=O)N1CCC(c2nccnc2OC2CCC(Nc3nc4ccccc4s3)CC2)CC1 +COc1cc(OCC2COC(C)(C)O2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CN(CCCCN1C(=O)CSC1c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)CCOc1ccc2c(c1)OCO2 +CC(C)C(CNC(=O)c1cccnc1Oc1ccc(Nc2ccccn2)cc1)c1ccccn1 +CC(C)(C)NCC(O)CON=C1c2ccccc2C2CCCCCC12O +CC1(C)CCc2[nH]nc(C(=O)Nc3cnn(Cc4ccccc4)c3)c2C1 +O=C(NOCC(O)CO)c1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +CC1=CC(C)(C)Nc2ccc3c(c21)C(c1ccc(Cl)c(Cl)c1)Oc1ccccc1-3 +COc1cccc2cc(C(=O)NCCC3CCN(Cc4ccccc4)CC3)c(=O)oc12 +CCNCCNc1cc(-c2ccc(C(F)(F)F)cc2)c(C#N)c2nc3cc(Cl)c(Cl)cc3n12 +Cc1ccc(C#N)cc1S(=O)(=O)N(C)CCc1cnn2ccc(Cl)nc12 +CN(C)CCCNc1[nH]nc(N)c1-c1nc2ccccc2s1 +CCS(=O)(=O)c1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2CN2CCCC2=O)cc1 +NS(=O)(=O)c1cc(-c2cnc(C3CCC3)o2)cs1 +OC(CC1c2c(F)cccc2-c2cncn21)C1CCCCC1 +CC(C)S(=O)(=O)c1ccn(C(CC2CCCC2)C(=O)Nc2ccn(C)n2)c(=O)c1 +Cn1c(=O)cnn(CCCCN2CCN(c3ccccc3S)CC2)c1=O +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCCCCCCNC(=O)C2CN(C)CCC2c2ccc(Cl)cc2)C1 +COc1c(C(=O)NC2CC3CCCC(C2)N3C2CCCCCC2)cc(Br)c2ccccc12 +Oc1ccccc1-c1cccc(-n2nnc(-c3ccccn3)n2)c1 +CN1C(=O)C(=N)c2c3ccccc3c(O)c3c(Br)ccc1c23 +CC1(CCCc2cc(=O)oc3nc(C(F)F)[nH]c(=O)c23)CC1 +CN1CCN(c2ccc(C(=O)Nc3cccc(CNc4ncnc5c(C(N)=O)cccc45)c3)cc2)CC1 +O=C(NC1COCCC1NC1CCCC1)c1ccc(C(F)(F)F)cc1C1CC1 +COc1cc(OC2CCN(Cc3cccnc3C)CC2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +N#Cc1ccc(-c2cccc(S(=O)(=O)N3CCC(N4CCCC4)CC3)n2)cc1 +COc1ccc2nc3cc(Cl)ccc3c(NCc3ccc4c(c3)OCO4)c2c1 +CCCc1nc(C)n2nc(S(=O)(=O)NC)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(Cn1ncc2c(=O)oc3ccccc3c21)Nc1ccc2ccccc2c1 +Cn1c(-c2cccc(-c3ccccc3)c2)ncc(O)c1=O +Cc1cccc(-c2ccnc(C(=O)Nc3ccc(Oc4ccnc5[nH]ccc45)c(F)c3)c2)c1 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+CCN1CCCC1CNC(=O)c1cc(I)cc(OC)c1OCCF +Cc1ccc(Oc2cn(C)c(=O)c(Nc3ccc(C(F)(F)F)cc3)n2)c(C)c1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(I)cc1-c1ccn[nH]1 +O=c1cc(-c2ccc(O)c(O)c2)oc2c(C3OC(CO)C(O)C(O)C3O)c(O)cc(O)c12 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CCCc2ccccc2)C(=O)CO)c1 +COc1cc(NC(C)CCCNCC2CCC3(CC2)OOC2(OO3)C3CC4CC(C3)CC2C4)c2ncccc2c1 +Cc1ccc(-c2ncccn2)c(C(=O)N2CC(COc3ccc(F)cn3)CCC2C)c1 +O=C1NC(=O)C2=C(CCCC2)C1=Cc1ccc(Cl)cc1 +O=[N+]([O-])c1ccc2nc(N3CCNCC3)cc(-c3ccccc3)c2c1 +Cc1c(CCN2CCN(c3ccc(F)c(Cl)c3)CC2)c2cccc3c2n1CCC3 +COc1ccc(-c2ccc(C(N)=O)cn2)cc1OC1CCCC1 +Cc1cc(-c2nc3cnc(N4CCOCC4C)cc3n2Cc2ccccn2)cn(C)c1=O +COCCOc1cc2ncnc(Nc3ccc(OC4CCN(C(=O)CC(C)(C)C)CC4)c(C)c3)c2cc1OCCOC +CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4ncc(=O)[nH]c34)c3ccccc23)n(-c2ccccc2)n1 +O=C1CCCc2nc(-c3ccco3)c3c(c21)C(=O)C=C(Nc1ccccc1)C3=O +O=C(CN1CCN(c2ccccc2)CC1)NC1c2ccccc2SCC2CCCCC21 +O=C(Nc1ccc(Oc2ncnc3[nH]cnc23)c(F)c1)c1cccn(-c2cccc(F)c2)c1=O +O=C(c1cccc([N+](=O)[O-])c1)c1ccc2ccc(C=Cc3ccc(O)c(O)c3)nc2c1O 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+O=C(CCCC(=O)NCCCCCCCNc1c2ccccc2nc2ccccc12)NCCCCCCCNc1c2ccccc2nc2ccccc12 +Cn1cc(CNc2cc(OCC3CC3c3ccc(Cl)cn3)nn(C)c2=O)cn1 +CN(CCc1ccccc1)C(=O)N1CC(OC(c2ccc(Cl)cc2)c2cccnc2Cl)C1 +Cc1cnc(-c2cc(C)c3nc(-c4c(NCC(O)c5cccc(Cl)c5)cc[nH]c4=O)[nH]c3c2)[nH]1 +COc1ccc(C=C2CNCC(=Cc3ccc(OC)c(OC)c3)C2=O)cc1OC +COc1cccc(-c2cc(C#N)cc3cc(C(N)(c4ccc(C#N)cc4)c4cncn4C)oc23)c1 +Cc1cc(COc2ccc(NC(=O)C3CCN(S(C)(=O)=O)CC3C(=O)NO)cc2)c2ccccc2n1 +COCCN(CCOC)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1SC +CCOc1ccc(N2C(=O)C(=Cc3ccccc3)N=C2SC)cc1 +NC(=O)C(NC1CCC(c2c[nH]c3ccccc23)CC1)C1CCN(C(=O)C=Cc2ccc(OC(F)(F)F)cc2)CC1 +COc1ccc(-c2ccc3nccc(Nc4cccc5[nH]ncc45)c3c2)cc1C=O +CC(C)(Cc1cc2ccccc2[nH]1)NCC(O)C1CCCN1Cc1cccc(C#N)c1 +N=C(N)c1ccc(CNC(=O)Cn2c(-c3cc(N)cc(C(=O)O)c3)c(Cl)nc(NCCCO)c2=O)cc1 +N#CC12CC3CC(C1)C(NC(=O)c1cnn4cc(CCO)cnc14)C(C3)C2 +O=C1NCCN1c1ccc(S(=O)(=O)Oc2ccccc2F)cc1 +CC(C)CS(=O)(=O)N1CCN(C(c2ccc(Cl)cc2)c2cncnc2)CC1 +O=c1sn(-c2cccc(Cl)c2)c(=O)n1Cc1ccc(F)cc1 +COc1ccc(-c2cc3cccc4c3n2CCNC4=O)cc1 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+O=C1NCC2c3c(cccc31)CCN2C(=O)C1CCCC1 +CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)N(CC)CCC(=O)O)n1 +Cc1c(Sc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)[nH]c2nc(N)nc(N)c12 +CC1(C)c2cc(N3CCOCC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +N=C(N)c1ccc(N2CCN(c3ccc(-c4nc5ccccc5[nH]4)cc3)CC2)cc1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(NC3CCN(C(=O)CO)C3)c2c1=O +COc1cc2c(cc1OC)C(=O)C(Cc1cccc(CN3CCCCC3)c1)O2 +COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccc(OCc3ccccn3)nc2c(=O)n1-c1ccc(N)cc1 +CCC(CN1CCS(=O)(=O)CC1)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CCOC(=O)c1cccc(-c2cnc3ccc(NC(CC)CO)nn23)c1 +O=c1c2cc(OCCCN3CCCC3)ccc2nc2n1CCCCC2 +CNC(=O)c1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 +CCC(C(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1)c1ccccc1 +N#Cc1cc(C(F)(F)F)ccc1N1CCC(N(c2ccc(Cl)cc2)c2cccnc2)CC1 +CC1C(N)=NC(C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CCS1(=O)=O +CC1CCN(C(=O)Nc2nc3c(s2)-c2nc(C(C)(C)C(F)(F)F)ncc2CC3)C1C(N)=O +Cc1cc(S(C)(=O)=O)ncc1Nc1ncnc(OC2CCN(C(=O)OC(C)C)CC2)c1C +O=c1ncn2nc(Sc3ccc(F)cc3Cl)ccc2c1-c1c(Cl)cccc1Cl +CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 +CN1C2CCC1CN(C(=O)c1cc3cc(Nc4nccc(-c5ccccn5)n4)ccc3[nH]1)C2 +CCOC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1cccs1 +CC(c1ccccc1CN)n1c(=O)oc2cc(S(=O)(=O)Nc3cccc(F)n3)c(F)cc21 +CC(CO)Nc1cc(NS(C)(=O)=O)nc(SCc2cccc(Cl)c2F)n1 +CC(C)c1nnc(NC(=O)NC23CC4CC(CC(C4)C2)C3)o1 +CCOc1ccc2c(c1Cl)C(=O)N(Cc1c(C)cc(C)[nH]c1=O)CC2 +Cn1nnnc1SCC(=O)OCC1(C)C(C(=O)O)N2C(=O)C(=CC(=O)O)C2S1(=O)=O +COc1ccc(-c2snnc2-c2cc(OC)c(OC)c(OC)c2)cc1 +COC1CCC2(CC1)Cc1ccc(OCC3(C)CC3)cc1C21N=C(C)C(N)=N1 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(NCCC(O)CO)c(-c2ccn[nH]2)c1 +FC(F)(F)c1cc(Br)cc(Nc2nccc(-c3cnn4ncccc34)n2)c1 +CCCC(=O)Nc1n[nH]c2ccc(-c3cccc(F)c3F)cc12 +CCC(CC)CC1CN(Cc2c[nH]c3c(N)ncnc23)CC1O +COc1cc(O)cc(OC)c1C1CNC(C(=O)N2CCCC2C#N)C1 +CC1CCC2C(C)C(CCOC(=O)CCC(=O)O)OC3OC4(C)CCC1C32OO4 +CCc1nnc(-c2cc(C(=O)N3CCC(F)(c4ccc(C#N)cc4)CC3)ccc2C2CCC2)[nH]1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccc(F)cc2)c1 +CNC(=O)C=Cc1cnc(N)c2c(-c3cc(F)c4[nH]c(C)cc4c3)csc12 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+CS(=O)(=O)CCNCc1ccc(-c2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2)[nH]1 +Cc1cc(N)nc(COCC(N)C(C)OCc2cc(C)cc(N)n2)c1 +CC(C)(COc1ncc(-c2ccc(-c3ncc(C4(C(F)(F)F)CCC4)[nH]3)cc2)cc1F)C(=O)O +CC(C)NC(=O)c1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4ccc(=O)n(CCO)n4)ccn23)c1 +CCC(O)(CC)c1ccc(NC2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)nc1 +C#CCn1c(=O)n(C)c(=O)c2c1nc(N1CCCC(N)C1)n2Cc1ccccc1C#N +CCNc1nc(-c2ccc(S(=O)(=O)CC)cc2)cc2ncn(C)c(=O)c12 +CCCCc1ccc2[nH]c(-c3ccc(OC)cc3)c(C=NNC(=O)c3ccccn3)c2c1 +NC1CCC(Nc2cc(-c3cccc(NCc4cccc(OC(F)(F)F)c4)n3)c(Cl)cn2)CC1 +Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCCc1ccc(F)cc1 +CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCCC(F)(F)F)c3Cl)C2)cc1 +CCSc1nc2cc(S(=O)(=O)NCc3ccc(OC)cc3)ccc2n1Cc1ccccc1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(CNC(=O)C2CC2)Nc2ccccc2C(=O)c2ccccc2)cc1 +CCCCC(C=C1CC(CO)(COC(=O)c2ccc(C)cc2)OC1=O)CC +Cc1cccc(-c2[nH]c(CNc3ccc(OC(F)(F)F)cc3)nc2-c2ccc3ncnn3c2)n1 +CC(C)(C)OC(=O)NCCCNc1cccc2ccc(-c3nnc4ccccn34)nc12 +CC(C)(CC(=O)N1CCC(O)C1)NCC(=O)N1CC(F)CC1C#N +ON=Cc1cnn2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc12 +Cc1cccc(NC(=O)NC2CC(c3ccccc3C)CC(c3ccccc3)N(CC(=O)NC(C)C)C2=O)c1 +CNc1c(C)c(C)nc2cc(C3CCCCN3C(=O)c3ccccc3NS(C)(=O)=O)nn12 +CONC(=O)c1ccc(C)c(Nc2ncnn3cc(NC(=O)NC(C)C)c(C)c23)c1 +COc1ccc(C(CC(=O)O)Nc2ncnc3c2CN(c2ccc(C)cc2C#N)CC3)cn1 +O=S(=O)(Nc1nccs1)c1ccc(Oc2cc(C(F)(F)F)nn2-c2cc(F)ccc2F)c(F)c1 +CC(C)C1C(=O)NC(CO)Cc2cc(NC(=O)C=CC=Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)ccc2N1C +CN(C(=O)Cc1ccc(C(F)(F)F)cc1)C(CN1CCCC1)c1cccc([N+](=O)[O-])c1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1c[nH]c2ccccc12)OCCc1c[nH]c2ccccc12 +CC1(C)Oc2ncnc(N)c2C=C1c1ccc2c(c1)CCC21CCC(CC(=O)O)CC1 +Cc1cc(C)n(CC2OC(n3cnc4c(Nc5ccc(Cl)cc5F)ncnc43)C(O)C2O)n1 +CNCCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCCOC2)c(=O)n4C)cn1 +CCOC(=O)c1ccc(CN2CC(C)(C)C(Oc3ccc(C#N)c(C(F)(F)F)c3)C2=O)o1 +CN(C)c1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)CCO3)cc1 +CCCc1[nH]c(=O)c(-c2csc(CS(=O)(=O)c3ccccc3)n2)cc1C(=O)OCC +CS(=O)(=O)c1ccc(C2SCCC(=O)N2Cc2ccccc2)cc1 +CC1CCCC(Nc2ncnc3c2nnn3Cc2ccccc2Cl)C1 +CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1C(=O)N(C)N(C)C(=O)c2ccccc21 +CCN(CCCCCC(=O)N(C)CCCCCCCCN(C)C(=O)CCCCCN(CC)Cc1ccccc1Cl)Cc1ccccc1Cl +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(NCCN1CCC(c2ccccc2)CC1)c1ccccc1 +Cc1cn2cc(C(F)(F)F)cc2c(C#Cc2cccnc2)n1 +CCC(CC)Oc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +N=C(NC1CC1c1ccccc1)NC12CC3CC(CC(C3)C1)C2 +Cc1cc(C(=O)N2CC(OCC(N)=O)C2)cc2c1-c1ccccc1C2(O)C(F)(F)F +Cc1ccc(-c2c3n(c(=O)c4ncccc24)CCCCCN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C3=O)cc1 +COc1ccc2c(c1)C(=O)CC(CCN1CCN(c3ccccn3)CC1)C2 +CCCCOC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(F)cc1F +O=S(=O)(c1cc(Cl)cc(Cl)c1)c1ccc2oc3c(c2c1)CNCC3 +O=C(c1n[nH]c2c1CCN(CCC(F)(F)F)C2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1C=Cc2c(ncn2-c2cnccn2)C1 +COc1cc(CCNC(=O)C=C(C)C)c2[nH]c3ccccc3c3ccnc1c23 +COc1ccc(C2=NN(C(C)C)C(=O)C2(C)C)cc1OCc1cccc2ccccc12 +O=C(NC(CO)c1ccccc1)c1ccc(-c2ccncc2)cc1 +O=C1Nc2c(ccc(F)c2F)C1(c1ccc(O)cc1)C1CCCCC1 +O=C(O)CCNc1sc2c(c1Cc1nnc(S)n1NC(=O)c1ccc(Cl)cc1)CCCC2 +COc1ccc(N2CCOCC2)c2sc(NC(=O)C(C)(C)Oc3ccc4c(c3)OCO4)nc12 +COc1nc(N2CC(C)(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +COCCN1CCn2cc(C(=O)OC(C)C(C)(C)C)c(C)c2C1=O +Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(C3CCCN3)nc12 +N#Cc1ccc(C(c2cccnc2)N2CCC(NC(=O)c3c(F)cccc3F)CC2)cc1 +COc1cccc(CCCCCCCc2cccc(OC)[n+]2C)[n+]1C +c1cc(CN2CCCCC2)cc(OCCCN2CCC(Cc3c[nH]cn3)CC2)c1 +O=C(NCCCN1CCC2(CCc3ccccc32)CC1)C(=O)c1c[nH]c2ccccc12 +Cc1cc(C(N)(c2ccc3c(c2)c(-c2cccc(Cl)c2)cc(=O)n3C)c2cncn2C)ccc1Cl +CCB(CC)OC(=O)C(N)CCCCNC(=S)Nc1ccc(S(=O)(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +NCCCCC(N)CNC1CC(N)C2(CCC(O)C(O)CO2)C(O)C1O +Cc1c(C)c(C(C)C)n(CCC2CC(O)CC(=O)O2)c1-c1ccc(F)cc1 +CCn1c(C(O)c2ccccc2Cl)nc2cnc(Oc3c(F)cccc3F)nc21 +CN(C)C1CCCCC1N(C)C(=O)c1ccc(Cl)c(Cl)c1 +Cc1cc(-c2ccc(NC(=O)C(CC(C)C)c3cccc(-c4ccc(N5CCOCC5)cc4)c3)cc2)ccn1 +CS(=O)(=O)NC(=O)c1cccc2nc(C=Cc3nc4c(N5CCOCC5)cc(Cl)nn4c3-c3cccnc3)ccc12 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+CC(C)c1onc(COc2c(Cl)cc(Cl)cc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +CNS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCC(F)(F)CC2)cc1F +CS(=O)(=O)c1ccc(C(F)(F)F)cc1NC(=O)Nc1cnc(Oc2ccc(-c3cc(F)cnc3N)cc2)nc1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(c4ccccc4OC)CC3)c(OC(F)F)c21 +COc1ccc(S(=O)(=O)N(Cc2ccc3c(c2)C=CC(C)(C)O3)C2CCC2)cc1OC +COc1ccc(NC(=O)C2c3ccccc3C(=O)N(C3CCCC3)C2c2cccs2)cc1Cl +C=CCCC(=O)Nc1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +Cc1ccc(C(=O)NC(Cc2ccccc2)c2nc(-c3ccc4c(N)n[nH]c4c3)c(Cl)[nH]2)cc1 +COc1ccc2c(c1)OCCCCCCCCCN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1 +COc1ccc2c(c1)CCC=C2CCCN1CCN(c2ccccc2OC)CC1 +COc1cc2c(cc1OC)-c1c(OC)c(O)c(Br)c3c1C(C2)N(C)CC3 +O=C(Cc1cccc(OC(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 +CC(NC(=O)c1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1)c1cccnc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCC3CCCO3)c2)[nH]1 +CCCc1cc(OC)cc2nc(-c3cccnc3N3CCN(C)CC3)oc(=O)c12 +COc1ccc(CC2(C(=O)OCc3ccccc3)CCCN2C(C)=O)cc1 +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1c(C)ccc1C +CCOc1cnc(OC)n2nc(NS(=O)(=O)c3c(Cl)cccc3Cl)nc12 +O=C1NCC2c3c(cccc31)CCN2C(=O)Cc1ccc(OCc2ccccc2)cc1 +OC(Cc1ccccc1)CN1CCN(CCSC(c2ccccc2)c2ccccc2)CC1 +CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(Cc1c[nH]c2ccccc12)NC(=O)C1CCCCN1 +C1=CC2(CCN(CCc3cccc4ccccc34)CC2)Oc2ccccc21 +O=S(=O)(Cc1ccccc1)N1CCN(c2ncccc2C(F)(F)F)CC1 +CC(C)(O)c1ccccc1-c1ccc2[nH]c(C=Cc3ccc(OC(F)(F)F)cc3)nc2c1 +CN1CCC(Nc2cccc(-c3nc4ccc(OCCCN5CCCC5)cc4o3)c2)CC1 +CC(=O)NCC(NC(=O)c1ccc(-c2nc(C3CCOCC3)cnc2N)cc1F)c1cc(F)cc(Br)c1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(-c3ccccc3)nc(-c3ccccc3)c2)CC1 +O=S(=O)(Nc1cccc(CO)c1)c1ccc(-c2ccc(F)cc2F)cc1 +O=C(NC1CNCCCC1OC(=O)c1cc(O)c(Cc2c(O)cccc2C(=O)O)c(O)c1)c1ccc(O)cc1 +CC(C)(C)N1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +O=C(Nc1cn(CC(=O)N2CC3CCCNC3C2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +COc1ccc2[nH]cc(C3CCN(CCCCn4c(=O)c(-c5ccccc5)c5ccccn5c4=O)CC3)c2c1 +CCC(C)N(C)C(=O)c1nc2ccccc2c(-c2ccccc2)c1CI +CCNc1ncc(-c2cn(-c3cc(C(=O)Nc4ccc(CN5CCN(C)CC5)c(C(F)(F)F)c4)ccc3C)nn2)cn1 +CC(C)OC(=O)C1=CN(C(=O)c2ccc(OCCN3CCN(C)CC3)cc2)CC(C)(C)c2c1[nH]c1ccccc21 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OCCF)c(C(=O)O)c2)c1 +O=c1[nH]c2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O +CCn1ccc(-c2cnc(C)nc2OCC2CC2c2ccc3ccccc3n2)cc1=O +COc1ccc(-c2csc(C(=O)NC3CCN(C(=O)OCc4cc(Cl)cc(Cl)c4)CC3)n2)cc1 +Brc1cccc(-c2[nH]ncc2-c2ccnc3ccccc23)n1 +C=CCC(C)(C(=O)NO)C(CC(C)C)C(=O)NC(CC1CCCCC1)C(=O)NCCc1ccc(S(N)(=O)=O)cc1 +COc1ccc(N(C)c2cnc(SCc3ccccc3)n2-c2ccc(F)cc2)cc1OC +O=C(CC1CC1)N1CCC(c2nc(-c3cccs3)no2)CC1 +CC(=O)Nc1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccccc2)sc2ccccc12 +CC(C)C(=O)NC1C(O)C=C(C(=O)O)OC1C(O)C(O)CO +O=C(c1cc2cc(O)ccc2[nH]1)c1cc2cc(O)ccc2o1 +CC1CN(c2sc(C(F)(F)F)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cnc2ccccc21 +O=C(CC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1)NCCc1c[nH]nn1 +Nc1ccccc1NC(=O)c1ccc(C=CC(=O)NCCc2c[nH]c3ccccc23)cc1 +COc1cc(CNc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc(OC)c1 +O=S1(=O)CCC(CNC2CCC(Nc3cc(-c4ccc(F)c(NCC5CCOCC5)n4)c(Cl)cn3)CC2)CC1 +CSc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C)n1 +CCS(=O)(=O)N1CC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CC(C)(N)C(=O)N1CCn2c(nc(-c3ccc(F)cc3)c2Nc2ccc(F)c(F)c2)C1 +COc1ccc(CNC(=O)CCCCCCCC(=O)NCc2ccc(OC)c(O)c2)cc1O +O=c1ccc(-c2ccc(OC3CCN(C4CCCC4)CC3)nc2)n[nH]1 +Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(CC(=O)N1CCCC1)C2 +O=C(Nc1ccc(-c2ccc(C(=O)C3CCCC3C(=O)O)cc2)cc1)Nc1cccc(C(F)(F)F)c1 +CCOC(=O)N1CCN(CC2CCCN2S(=O)(=O)c2ccc3c(c2)C(=O)C2=NCC(C)(C)CN23)CC1 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2(O)CCCNC(=O)CI +Cc1ccc(C(=O)Nc2sc(Nc3ccc4cc(CO)ccc4c3)nc2C(N)=O)s1 +Cc1cc(Nc2nc(NC(C)c3ccc(F)cn3)c(F)c(N3CCN(S(C)(=O)=O)CC3)n2)n[nH]1 +Cn1nc(NC(=O)Cc2ccccc2)c(-c2ccncc2)c1-c1ccc(F)cc1 +O=C(NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O)c1ccc2c(c1)nc(-c1cccs1)n2C1CCCCC1 +COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1 +Cc1ccc(C)c2nc3c(C(=O)NCCCN(C)CCCNC(=O)c4cccc5cc6c(C)ccc(C)c6nc45)cccc3cc12 +CC(=O)c1cc2c(o1)C(=O)c1c(O)cccc1C2=O +CN(C)CCNC(=O)c1cccc(NC(=O)Nc2ccc(N(CCCl)CCCl)cc2)c1 +CC(O)CCc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O +CC(C)Sc1ccc(CC2CCN(C3CCN(C(=O)c4cccc5cc(F)ccc45)CC3)CC2)cc1 +Cc1cc(CNC(=S)CCc2ccc(C(C)(C)C)cc2)ccc1NS(C)(=O)=O +COc1ccc2c(=O)cc(C=Cc3ccc(O)c(O)c3)oc2c1OC +O=C(C=Cc1noc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(O)cc1)N1CCN(c2ncccn2)CC1 +NC(=O)c1c(NC(=O)c2ccc(OCc3ccccc3)cc2)sc2c1CCN(C(=O)c1ccccc1)C2 +O=C(NO)C1CC(O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1 +Nc1cccc2cc3c(=O)[nH][nH]c(=O)c3cc12 +COc1ccc(Nc2ncc3c(n2)-c2ccc(F)cc2NC(=O)C3)cc1OC +CN(C)CC(Cc1ccccc1)c1cccc(OCCNS(=O)(=O)c2cnn(C)c2)c1 +O=C(OCCCc1ccc(F)cc1)C1CCCCN1S(=O)(=O)Cc1ccccc1 +CCn1nnc(C2OC(n3cnc4c(NC5CC6CCC5C6)ncnc43)C(O)C2O)n1 +CC(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1 +CN(C)CCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 +CCNc1c2c(nc(NC(=O)Nc3ccc(OC)cc3)n3nc(-c4ccco4)nc23)nn1C +Cc1cccc2scc(Cn3c(SCCCC(=O)O)nc4ccccc43)c12 +O=C1c2ccccc2C(=O)N1CC=CCN1CCN(Cc2ccc(Cl)cc2)CC1 +COc1cc2ncnc(N3CCN(C(=NCc4ccc(Cl)cc4)NC#N)CC3)c2cc1OC +O=C(Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cn1)c1ccccc1Cl +CCN(CC)Cc1cc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)c2ccccc2)ccc1O +CN(C)c1ccc(-c2cn(-c3ccc(OCCOCCOCCO)cc3)nn2)cc1 +Nc1nc2c(ncn2C2CC(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1 +COC(=O)C(C)NP(=O)(OCC1OC(C)(C)OC1C(=O)NO)Oc1cccc(C)c1C +NC1CCN(c2cncc(-c3n[nH]c4ccc(-c5c(F)cccc5F)cc34)n2)C1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(OCC)cc(-c3ccccc3)n2)CC1 +Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1ccnc(N2CCOCC2)c1 +COc1cc(N)c(Cl)cc1C(=O)OC1CC2CCC1CN2C +O=C(CCCCCNC(=O)Nc1cccc(-c2nc3ccc(F)cc3o2)c1)NO +Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3[nH]nnc3n2)c(OC(C)C)cc1C1CCN(C)CC1 +COc1ccc(C(=N)NCCCCCCCCCCCCNC(=N)c2ccc(OC)c(OC)c2)cc1OC +c1ccc(CN2CCCC(n3cnc4cnc5[nH]ccc5c43)C2)cc1 +CC(=O)NC1CCN(c2ccc3c(C=O)c(O)ccc3n2)C1 +CN(c1ccc2c(c1)C(=NNC(=N)N)CC2)S(=O)(=O)c1c(Cl)nc2sccn12 +O=C(c1cccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)c1)N1CCOCC1 +COc1cc(Cl)c(C=NNC(=O)CSc2cc(C)nc3ccccc23)cc1OC +CC1(C)C=Cc2c(ccc(-c3coc4cc(O)ccc4c3=O)c2O)O1 +[C-]#[N+]c1ccc(CCc2ccc3c(-c4ccc(OC)cc4F)cc(C(N)=O)nc3c2)cn1 +CC(C)(O)c1cc(-c2ccc(S(N)(=O)=O)cc2)c(-c2ccc(F)cc2)s1 +CCC(CO)Nc1nc(NCc2ccc(-c3ccccn3)cc2)c2[nH]nc(C(C)C)c2n1 +Cc1cncc(-c2cc3c(cnn3-c3cccc(N4CCNCC4)n3)nn2)n1 +CCCN1CCc2cc(OCCF)cc3c2C1Cc1cccc(O)c1-3 +COCC1CCCN1c1cc(NC(C)=O)nc(-c2ccc(C)o2)n1 +COc1ccc(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(OCCN4CCCCC4)cc3)n2)c(OC)c1 +O=C(NCc1nc2ccccc2c(=O)n1-c1ccc(F)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)NCc5c(Cl)cccc5C(F)(F)F)cn4c3)cc2)CC1 +CC(C)NC(=O)N(Cc1cccc(C#Cc2ccncc2)c1)Cc1cccc(C#Cc2ccc(Cl)cc2)c1 +Nc1[nH]c2cc([N+](=O)[O-])ccc2c1-c1ccccn1 +CCc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 +COC(=O)C(NC(=O)NC(C(=O)NC1CCCCNC(=O)C=CC(Cc2cccc(F)c2)NC1=O)C(C)C)C(C)C +O=C(c1ccc(Cl)c(Cl)c1)N1CCC(CNCCc2cccnc2)CC1 +N#Cc1c(Cl)cc(Cl)cc1-c1cccc(C(=O)CC(=O)C(=O)O)c1 +COc1nc2c(cc1C(=O)N1CCn3c(cnc3-c3ccc(F)cc3F)C1)c(C(=O)C(=O)N1CCC(O)C1)cn2C +NCCc1c[nH]c2ccc(OCC(=O)N3CCN(c4ccc(CN)cc4)CC3)cc12 +Cc1nc(C#Cc2cncc(-c3ccc(CO)cc3)c2)cs1 +O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)Oc1ccccc1 +O=C(Nc1ccc(C(=O)N2CC3COCCN3Cc3ccccc32)c(Cl)c1)c1cc(F)ccc1-c1ccccc1 +Nc1nc(N)c(NC(=O)Nc2ccc(C(=O)NC(CCCC(=O)O)C(=O)O)cc2)c(=O)[nH]1 +CCNC(=O)Nc1nc2cc(-c3cccnc3)c(=O)n(C(C)C(N)=O)c2s1 +Cc1ccc(C(=O)Nc2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cnc(N(C)CCN(C)C)nc12 +Cc1cc(NS(=O)(=O)C(C)(C)C)ccc1-c1c(C(N)=O)c2cc(F)c(OC(F)F)cc2n1-c1ccccc1 +CC1C2c3cc(O)ccc3CC(c3ccc(O)cc32)N1C +CS(=O)(=O)OCc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1 +CCNC(=O)C1OC(n2cnc3c(N(C)C)ncnc32)C(O)C1O +O=C(CCCN1CCC(CO)(c2ccc(Cl)cc2)C1)c1ccc(F)cc1 +COc1cccc(-c2ccc3c(c2)C2(COC(N)=N2)C2(COC2)C(C)(C)O3)c1 +NC(CC(CCC(=O)NOCc1ccccc1)C(=O)O)C(=O)O +Cc1cc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cnc1F +O=C(NCC1CC1CN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2ccccc2[nH]1 +COC1(C)CCC(Oc2n[nH]c3cc(NC(=O)NC(COC(F)F)c4ccccc4)ncc23)CC1 +CCNC(=O)Nc1cn2c(-c3nc(C)cc(C(F)(F)F)n3)cc(-c3cccnc3)cc2n1 +COc1cccc2sc(C3CCN(CC(O)COc4cccc5[nH]ccc45)CC3)cc12 +CC(C)C(NC(=O)C1CCOCC1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)C(F)(F)F)C(C)C 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+CC(C)(NC(=O)c1cccc(-c2cccc(Cl)c2)n1)c1ncco1 +CC(C)NS(=O)(=O)c1ccc(-c2ccc3c(cnn3-c3ccc(F)cc3)c2)c(C(F)(F)F)c1 +CN1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 +OC1CCC(c2cccnc2Oc2ccc(Nc3nc4ccccc4s3)cc2)CC1 +c1cc2[nH]cc(-c3cncc(C4CC4)n3)c2cc1-c1nnc(NC2CC2)o1 +Nc1cccc2ccc(-n3c(-c4ccnc(NC5CCOCC5)c4)n[nH]c3=O)cc12 +O=C(C=Cc1ccc(CNCCc2c(-c3ccccc3)nn3ccccc23)cc1)NO +CN(C)CC(=O)NC(c1ccc(Cl)cc1)c1nc2ccc(-c3cn[nH]c3)cc2c(=O)[nH]1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(C)ccc3nc2-1 +O=C(Nc1csc(-c2nncn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC3(CCOCC3)C2)cn1 +CCOC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2c1=O +Cn1c(SCCCN2CC3CCN(c4ccc(F)cc4C(F)(F)F)C3C2)nnc1-c1cnccn1 +N=C(N)NCCCC1CC(OCc2ccc3ccccc3c2)CN1C(=O)C(Cc1ccccc1)NC(=O)C1Cc2ccccc2CN1 +CCOC(=O)c1c(-c2ccc3c(c2)OCO3)[nH]c2cc(OC)c(Cl)cc2c1=O +Cc1cc(Cl)c(NC(=O)N(Cc2ccc(Oc3ccc(F)cc3)cc2)C2CCCCCC2)c(Cl)n1 +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2nc(CN3CCC(c4ccc(F)cc4)CC3)ccc2c1 +O=C(N1CCN(Cc2ccc([N+](=O)[O-])cc2)CC1)n1nnc2ccccc21 +NC(=O)CCc1c(-c2ccccc2)c(O)nc2cc(Cl)ccc12 +COc1ccc(F)cc1CNCCCNc1ccnc2cc(Cc3ccc(C#N)cc3)ccc12 +COc1cc(C=CC(=O)NCCn2c(C(F)(F)F)cc3ccccc32)cc(OC)c1OC +CCCCOC1Oc2ccccc2C(=O)C1=CNc1cccc(S(N)(=O)=O)c1 +CCN(CC)CCCNc1nc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2o1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1Oc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 +CC1(C)Oc2cc(C34CC5CC(CC(N=C=S)(C5)C3)C4)cc(O)c2C2CC(O)CCC21 +CS(=O)(=O)N1CCc2c(c(-c3ccc(Br)cc3)nn2CC(O)CN2CCC(N3CCCc4ccccc43)CC2)C1 +O=c1ccc2cnc3ccc(-c4cnc5[nH]ccc5c4)cc3c2n1-c1ccc(F)c(C(F)(F)F)c1 +Cc1ccc(C(=O)Nc2cc(-c3c(-c4ccc(F)cc4)nc4n3CCS4)ccn2)cc1F +CSc1nn2cc(-c3nc4c(C)cc(Cl)cc4s3)nc2s1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)c4cccc(OC(F)(F)F)c4)nc23)N1 +CCOC(=O)NC1N=C(c2ccccc2)c2ccccc2-n2c(C)nnc21 +COc1cc(N2CCN(C3CCN(c4cccc5c(C)cc(C)nc45)CC3)CC2)c2ncccc2c1 +Oc1ccc(-c2nn(Cc3ccccc3)c3c(Cl)cccc23)cc1 +COc1cc[nH]c1C=C1C(=O)Nc2ccc([N+](=O)[O-])c(N3CCC(N)CC3)c21 +CCCN1CCC2(CC1)Oc1ccccc1C1CC(c3ccc(F)cc3)=NN12 +CC(COC(=S)Nc1ccc(Cl)cc1)NC(=O)c1ccccc1C(=O)O +COc1cc(-c2cc(F)c(F)cc2F)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +COc1ccc(COc2ccc3c(Cn4ccnc4)cc(=O)oc3c2)cc1 +CCCN(CCC)c1cccc2nc(Nc3c(OC)cc(COC)cc3OC)c(C)cc12 +O=C(OCCCCN1CCN(CCO)CC1)c1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O +O=C(NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)NC(Cc1ccncc1)C(=O)O +COc1cccc(N2CCN(CCN3CCCCCC3)C2=O)c1 +C=Cc1cccc2c1N1CCCC(NC(=O)C(F)(F)F)C1c1ccccc1O2 +CN(C(=O)c1ccc(NC(=O)Cc2ccc(NC(=O)C3CCN(C(=O)c4ccccc4)CC3)cc2)cc1)C1CC1 +Cc1nc2c(o1)CN(C1COC(c3cc(F)ccc3F)C(N)C1)C2 +COc1cc(C(O)P(=O)(O)CCC(N)C(=O)O)ccc1OCC(=O)O +O=c1cc(CSc2nnc(-c3cccs3)n2Cc2ccccc2)nc2sc3ccccc3n12 +CCN(Cc1ccccc1)Cc1ccc(C=CC(=O)NO)o1 +O=C(CCN1CCOCC1)Nc1ccc(-c2cccn3c(=O)cc(N4CCOCC4)nc23)c2oc3ccccc3c12 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2cc(-c3ccc(C(=O)O)cc3)ccc2c1 +COc1ccc(-c2ccc3nccc(Nc4cccc5[nH]ncc45)c3c2)cc1F +COc1ncnc(Cn2cc(C(=O)NCCF)c3ncc(C(F)(F)F)cc32)c1C +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)CC1CCCNC1)C2 +Cc1cc(NC2CCN(CCC(=O)O)CC2)nc(NCc2cn(CCCNCCCNC3CCCCC3)nn2)n1 +CC1=CCCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(C)CCCOC2)c1O +COc1ccc(-c2cccc(CN3CCN(c4ncccn4)CC3)c2)cc1 +CCN(CC)CCCC(C)N=c1cc(C=Cc2ccccc2Cl)[nH]c2cc(Cl)ccc12 +Cc1cc(C)nc(N=C(N)Nc2ccc(S(=O)(=O)O)cc2)n1 +CC(C)n1cnc2c(Nc3ccc(-c4ccccc4)cc3)nc(NC(C)(C)CO)nc21 +Clc1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 +O=C(O)C1Cc2cc(-c3ccccc3)ccc2CN1C(=O)C(c1ccccc1)c1ccccc1 +CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1 +Cc1ccc(NC2CCCN(C(=O)c3ccccc3-n3nccn3)C2C)nc1 +Cc1cccc(Cl)c1-c1ccc(N2CCOc3ncnc(N)c3C2=O)cc1 +Cc1cccn2cc(-c3ccc(OCCCN4CCCCC4)cc3)nc12 +CCOP(=O)(CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(C)c3ccccc3)c2)[nH]1)OCC +CC(NC(=O)Nc1cc2[nH]nc(NCc3ccncc3)c2cn1)c1ccccc1 +CC(C)(C)C(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +O=C(CCCCc1ccc2c(n1)NCCC2)NCC(C(=O)O)c1ccccc1 +COc1cc(C(C)NC(=O)Nc2cc3[nH]nc(OC)c3c(CO)n2)ccc1Cl +C=C1C(=O)C23CC1CC(O)C2C12CCCC(C)(COC(C)=O)C1C(O)C3(O)OC2 +O=C(Nc1ccc(F)cc1)c1cc(O)c2cccc(O)c2n1 +CCN(Cc1ccc(C#CCCO)cc1)CC1CCCN(CCc2cccc(F)c2)C1 +N=C(N)c1ccc(N2CCC(N3CCN(CC(=O)O)CC3)CC2)cc1 +CCC(Nc1ccc(Cl)c(CN2CCC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 +C=Cc1cccc2nc3c(cc12)Cn1c-3cc2c(c1=O)COC(=O)C2(O)CC +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1-n1cccn1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1cccc(N(C)C)c1 +O=C(Nc1ccc(F)cc1)N1CC2CCN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1 +Cc1ncc(C)n2nc(CCc3nc(-c4ccoc4)cn3C)nc12 +Cc1cc(SCC=CC(C#Cc2ccccc2)c2ccc(Br)cc2)ccc1OCC(=O)O +CC(O)C(C)Nc1nc(Nc2ccc([S+](N)[O-])cc2)ncc1Br +O=C(O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O +CN1C(=O)C(NC(=O)Nc2cccc(N(C)c3nn[nH]n3)c2)N=C(c2ccccc2)c2ccccc21 +CCC(CS(=O)(=O)C(C)(C)C)N1C(=O)C(C)(CC(=O)CO)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +NC(=O)C(N)CCC(=O)Nc1ccc(Cc2ccccc2)cc1 +Nn1c(SCc2ccc(F)cc2)nnc1-c1c[nH]c2ccccc12 +CC(C)(O)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CCOC(=S)SCCCCCC=C(NC(=O)C1CC1(C)C)C(=O)O +CC(NC(=O)C(NC(=O)CCc1ccccc1)C(C)C)C(=O)NC(CC(=O)O)C(=O)CCCCc1ccccc1 +O=C1Nc2cc(-c3ccc(O)cc3)ccc2C1=Cc1ccc[se]1 +COc1cnc(N2CCN(C(=O)Cn3cc(-c4ccc(F)c(C)c4)nc3-c3ccccc3)CC2)nc1 +CN(C)C(=O)C(=O)N(C)C(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +CNc1nc2[nH]c(-c3cccc(CNC(=O)CCN(C)C)n3)cc2c2c1ncn2C +CC(C)(C)n1cc2c(n1)C(=O)CC1(CCN(C(=O)c3ccc4[nH]ncc4c3)CC1)O2 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCC2CCC3CC2C3(C)C)cc1F +O=C(CCCCCCCn1cc(-c2ccc(-c3ccncc3)cc2)nn1)NO +Nc1cc(C2CCCNC2)nc2c(-c3cccc(O)c3)cnn12 +COc1ccc(C(CCCCCCc2ccc3c(n2)NCCC3)CC(=O)O)cn1 +OC(CCN1CCN(c2ccc(Cl)cc2)CC1)c1cccs1 +COCC1CCN(C(CCc2ccccc2)C(=O)NC(Cc2cc(F)cc(F)c2)C(O)CNCc2cccc(OC)c2)C1=O +CCOc1ccc2ccccc2c1-c1cc2nc(N)nc(N)c2cc1C +COc1ccc2c(c1)c(=O)c1c(NCCN(C)C)ccc3ncn2c31 +O=C(O)c1cc(S(=O)(=O)Nc2ccc(Br)cc2Br)c2ccccc2c1O +O=C(CCN1CCCC1)NC1CCC(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +O=C(Nc1ccc2sc(-c3cccc(F)c3)nc2c1)N1CCCCC1 +CCCn1cc(-c2cnc3ccc(NC(=O)NC(C)CCCc4ccccc4)nc3n2)cn1 +CCOc1ccc(Cc2nc3cc(SCC)c(Cl)cc3n2CC2CCOCC2)cc1 +Cc1cnc(Nc2ccc(C#N)cc2)nc1Cc1c(F)cccc1F +CCCC(=O)NCCCc1cccc2nc(-c3ccccc3)oc12 +CCN(CC)CCOc1ccc(Nc2cc(N(C)C(=O)Nc3c(Cl)cccc3Cl)ncn2)cc1 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+O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)ccc2n1CCC(=O)n1ccnc1 +CCC(OC)(c1cc(F)cc(OCc2ccc3c(ccc(=O)n3C)c2)c1)c1nccs1 +OC1(c2ccc(Cl)cc2)CCN(Cc2c[nH]c3ccccc23)CC1 +CC(C)c1n[nH]c2c(NCc3ccc(-c4ccccn4)cc3)ncnc12 +CC(=O)Nc1cccc(C2CCN(CCCn3nc(-c4ccc(Cl)cc4)c4ccccc4c3=O)CC2)c1 +CCc1nc(N)nc(N)c1C#CCc1cc(OC)ccc1OC +O=C1NC2CCc3cccc(c32)-c2c1[nH]c1ccccc21 +Cc1cc(-c2nnc3n2CC(C)N(Cc2cccc(C(F)(F)F)c2Cl)C3=O)n[nH]1 +O=C(Nc1ccc(C2CCCNC2)cn1)c1ccc(Cl)cc1 +CCCSC(=O)N1CC(C(C)OC(=O)CCCc2ccccc2)C1=O +COc1ncc(-n2nc(C)c3c2C(=O)N(c2cc(C)c(=O)n(C)c2)C3c2ccc(Cl)cc2)c(OC)n1 +CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-c4ccccc4)ccc3n2)cc1 +O=C(Nc1cccc2[nH]ncc12)NC1CCC(c2ccc(C(F)(F)F)cc2)C1 +O=C(N1CCOCC1)N1CCN(c2ccc(Cl)cc2)CC1 +CC1(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2F)CS(=O)(=O)C2(CCCCC2)C(=N)N1 +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CC2(CC(O)CO2)C1 +CC(=O)c1cccc(CN(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)S(=O)(=O)c2ccc(OCC(=O)O)cc2)c1 +CSc1ccc(C2CN(C)Cc3cc(Oc4ccnc(CN5CCCCC5)c4)ccc32)cc1 +COc1nc(N2CC(F)(F)C2)nc(OC)c1NC(=O)CC(C)(C)C 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+CCCCN1CCC(CNC(=O)c2c3n(c4ccccc24)CCCO3)CC1 +CC(C)Oc1cc2c(cc1NC(=O)c1ccncc1)n(C)c(=O)n2C +CC1COCCN1c1cc(CS(C)(=O)=O)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 +CC(c1nc2ccc(N3CCCC(C(=O)N4CCCC4)C3)nc2[nH]1)n1cc(Cl)cn1 +Nc1cnc(-c2ccc(C3CCC3)c(Oc3ncc(C(F)(F)F)cn3)c2F)cn1 +Cc1cc(Oc2ncc(Cl)cc2Cl)ccc1-c1c(C)c(=O)[nH]c(=O)n1C +N=C(N)c1csc(CNC(=O)C2CCCN2C(=O)C(NS(N)(=O)=O)C(c2ccccc2)c2ccccc2)c1 +O=C(c1ccc(C(=O)N2CCC(N3CCCC3)CC2)cc1)N1CCCC(N2CCCC2)CC1 +CC(C)Oc1ccc(NC(=O)C2CC3CCC2N(S(=O)(=O)c2ccccc2F)C3)cc1 +CCCN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCC1 +CC1(O)CCC(Nc2c(C(N)=O)cnn3cc(-c4cncnc4N)cc23)CC1 +CCCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCC1)CC2 +O=C(Nc1nc(CF)cs1)c1cc(Cl)cc(Oc2cncnc2)c1 +Cc1c(C(=O)NCCCN2CCOCC2)sc2ncnc(Nc3cccnc3OC(C)C)c12 +CCOC(=O)c1nn(C(=O)c2ccccc2)c2ccc(OC(F)(F)F)cc12 +CCOc1csc(-c2ccc(OCCCOc3ccc4c(c3)CCC4CC(=O)O)cc2)n1 +CC(Cc1ccccc1)(NC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)N1CCC2(CCCC2)CC1)C(=O)O +CCCn1cc(-c2cccc(-c3cnc(N)c(C(=O)NC4C5CC6CC4CC(O)(C6)C5)n3)c2)cn1 +COc1ccc(C2c3nc(CCC(=O)O)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)cc1 +CCCCc1nc(CCCC)n(Cc2ccc(-c3ccccc3-c3nn[nH]n3)nc2)n1 +Cc1cn(C2CCCCC2)c2cc(C(=O)Nc3c(Cl)c[n+]([O-])cc3Cl)ccc12 +Cc1nc(C(C)N(Cc2ccccc2Cl)c2ccc(C#N)c(Cl)c2)cs1 +CCCC(CNC(CNC)Cc1ccc(O)cc1)NCC1CCCCCC1 +Cc1sc(-c2cc(F)cc(F)c2)nc1CSc1nc(N)cc(N)n1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2ccccc2F)cc1 +Cc1nn(C(C)(C)C)cc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2nncs2)cc1Cl +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(CC(=O)NO)c1ccccc1 +CC(C)N1CCCC(n2cc(S(=O)(=O)c3ccc(Cl)cc3)c3cccnc32)C1 +CCCCC(C=NNC(=O)SC(C)C)NC(=O)OC(C)(C)C +CC(C)c1cc(C(C)C)c(S(=O)(=O)NC(Cc2cccc(C(=N)N)c2)C(=O)N2CCOCC2)c(C(C)C)c1 +Cc1ccc(Oc2ccc3c(c2)CC(NCC(O)c2cccc(Cl)c2)CC3)cc1C(=O)O +COc1cccc(C23CCN(C)C(C2)C(=Cc2ccccc2)C(=O)C3)c1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1cnc(C#N)c(Cl)c1 +CC1(C)CC(C)(C)CC2(C1)OOC1(CC(C)(C)CC(C)(C)C1)OO2 +O=C(Nc1nc2cc(C(F)(F)F)cc(NC3CC3)n2n1)c1cccnc1 +CCCOCCn1c(=O)c(NCCO)nc2cnc(-c3ccc(OC)nc3)cc21 +CN(C)CCn1cnnc1-c1cc(Oc2ccc(NC(=O)NN=Cc3ccc(Cl)cc3Cl)cc2F)ccn1 +CC1(C)C2CC=C(C[N+](C)(C)Cc3ccc(-c4cccc(Cl)c4Cl)cc3)C1C2 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4cnc(-c5ccncc5)s4)s3)c2)C(O)C(O)C1O +CNCCn1cc(-c2ccc(F)c(C)c2)nc1C1CCN(c2ncnc(N)c2C(N)=O)CC1 +Cc1cc(-c2ccc(C(=O)c3cccc(O)c3)nc2)ccc1O +CCN1CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)CC1=O +CC1Cc2c(ccc(C3CN4CCN(C(=O)C5CCc6nc(-n7cnnn7)ccc65)CC4CO3)c2F)C(=O)O1 +O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2oc(-c3ccccc3)cc21 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(C(F)(F)F)ccc1NC(=O)N1CCC1 +CCOC(=O)c1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3cccnc3)c2c1 +CNC(=O)c1ccc(F)c(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1 +COc1cc(Nc2nc3cccc(-c4cccc5[nH]cnc45)c3o2)cc(OC)c1OC +CC(C)(NC(=O)Nc1nc(-c2ccncc2)cs1)c1ccccc1 +CC(C)Oc1cccc2c1C(=O)N(COC(=O)c1c(Cl)cccc1Cl)S2(=O)=O +CC(C=CC=C(C)c1cc(C(C)C)cc(C(C)C)c1OCC(F)(F)F)=CC(=O)O +Cc1nc2cc(F)ccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2ccccc2)CC1 +Cn1cc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)c(F)c2)cn1 +O=C(C=CCN1CCCCC1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1 +CCN(CC)c1ccc(CN2CC(C)C(c3nn4c(C5CCOCC5)ncc4c(=O)[nH]3)C2)cc1 +O=C(O)CCn1cc(Cn2ccnc2)c2ccc(C(F)(F)F)cc21 +CN1CCc2cc(Cl)c(O)cc2C2c3ccc(N)cc3CCC21 +CC1=C(c2ccc(O)cc2)C(=O)c2cc(O)ccc21 +O=C(c1nnc(-c2ccccc2)o1)N1CC(Oc2ccc(CN3CCCC34CCOC4)cc2)C1 +Cc1cccc(COC(=O)N2CCc3ncsc3C2c2cc(Cl)ccc2OCC(=O)O)c1C +COc1cc(-c2cc3ncccc3c(NCC3CC(=O)NC3C)n2)cc(OC)c1OC +O=C(Nc1ccc(-n2ccnc2)cc1)C1=C(O)CC(Cc2ccccc2)NC1=O +COc1ccc(S(=O)(=O)NCCCCc2cc(C(=O)O)c3ccc(C(C)C)ccc2-3)cc1 +COCCOc1ccc(Nc2c(C)c(NC3CCCNC3)nc3ccnn23)cc1 +CCNC(=O)C1OC(n2cnc3c(NC(=O)Nc4cccc(Cl)c4)ncnc32)C(O)C1O +O=C(NC1CCCCC1NCc1ccc(Cl)c(Cl)c1)c1ccc2ccccc2c1 +CCCc1nn(C)c2c(O)nc(-c3cc(S(=O)(=O)N4CCN(C(N)=O)CC4)ccc3OCC)nc12 +Cc1c(-c2ccc(=O)n(Cc3ccc(F)cc3F)n2)c2cc(F)ccc2n1CC(=O)O +CC1(C)CC(N2CCN(C(c3ccccc3)c3ccccc3)CC2)=CC(=[N+]2CCCCC2)C1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4ccccn4)ccn23)c1 +CC(C)Oc1ccc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)cc1C#N +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3c(C)ccc4[nH]nc(C)c34)nc(OCCN3CCOCC3)c2C1 +COc1cc2[nH]c(C)c(-c3ccc(C(F)(F)F)cc3F)c(=O)c2cc1Cl +CCCOC(=O)NCc1nc(-c2nc(C)cs2)c(-c2ccc3ncsc3c2)[nH]1 +CC1(C)Oc2nc([N+](=O)[O-])cn2CC1OCc1ccc(OC(F)(F)F)cc1 +CC(C)(C)OC(=O)NCCNC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 +N#CCCNCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +Cc1cn(C2CC(O)C(COP(=O)(O)CP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O +O=C1CC(=O)CC(c2cc(-c3ccccc3)cc(C(F)(F)F)c2)C1 +CC1Cn2c(nnc2-c2ccc(F)cn2)C(=O)N1Cc1cccc(C(F)(F)F)c1Cl +CCOc1ccc(-n2nc3c(N4CCC(OC)C4)nnc(C)c3c2C)cc1 +C=CC(=O)N1CCCc2[nH]c3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn3c2C1 +Cc1c(C#N)cc2nc(O)c(O)nc2c1[N+](=O)[O-] +COc1ccc(C(=O)Nc2c(F)cncc2F)c2ccc(C(F)(F)F)nc12 +CCNC(=O)CN1CCCC(NC(=O)c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)C1 +Cc1cc(-c2nnc(N)nc2-c2ccccc2)cc(C)c1O +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCc2c(Cl)ccc3c2C(CCC3)C1 +CCCc1nc(-n2cccc2C(=O)O)c(C#N)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(C)(O)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 +CC(=O)SC1CC(COCc2cc(F)c(F)cc2F)N(C(=O)Oc2cccc3c2OCCO3)C1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccc(O)cc3)[nH]c2c1 +CC(CO)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2)cc(C(=O)Nc2nccs2)c1 +CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C#N)cc3)c2)CC1 +CCCCC1Nc2ccc(CC)cc2C(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cn1c2c(c3cc(S(=O)(=O)c4ccc(C#N)cc4)ccc31)C1CCC(C2)N1 +O=c1[nH]cnc2c(CNC(CO)CC(F)(F)P(=O)(O)O)c[nH]c12 +O=c1[nH]c2ccc(Br)cc2c(C=Cc2ccccn2)c1-c1cccs1 +COc1ccc(C2Cc3c(cccc3C(F)(F)F)N(CCN(C)C)C(=O)C2C)cc1 +CNc1nc(NC)nc(NCCc2ccc(S(N)(=O)=O)cc2)n1 +NCC1CCn2cc(c3ccccc32)C2=C(C(=O)NC2=O)c2cn(c3ccccc23)CCO1 +CCCC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc32)cc1 +CCOc1cc2cc(CO)c(CO)c(C3=CCN(CCOC)C(=O)C3)c2cc1OC +Cc1ccc(C(=O)N2CCC2c2nnc(-c3ccccc3OC(F)(F)F)[nH]2)c(-n2nccn2)c1 +Cc1cc(F)ccc1Oc1cc(Cl)c(Cl)cc1C(=O)Nc1ccc(C(=O)O)cc1 +O=C(c1c(O)ccc2cccnc12)N1C2CCC1C(COc1ccccn1)C2 +O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(OCc2ccccc2Cl)cc1 +CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccc5ccccc5c4)cc3c-2c1CC +COc1nc(N)c(Cl)cc1C(=O)NC1CC2CCCC(C1)N2C +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccccc1 +CNC1=Nc2ccc(N(C)Cc3ccnnc3)c3cccc1c23 +O=C(O)c1csc(-n2nc(-c3cccc(-c4ccccc4)c3)cc2O)n1 +CCCCC#Cc1nc(NC)c2ncn(C3C(O)C(O)C4CC43)c2n1 +CCCn1c(=O)c2[nH]c(-c3ccc[nH]3)nc2n(CCCOC)c1=O +CCCCN1C(=O)C(=CNCC2CCC2)C(=O)c2cccc(C)c21 +O=C(NCc1cc(F)ccc1F)Nc1ccc(S(=O)(=O)N2CCC(CNCC(O)COc3ccc(O)cc3)CC2)cc1 +CCOC(=O)C1=C(Nc2ccc(F)cc2)CC(c2ccc(Cl)cc2)N(c2ccc(F)cc2)C1c1ccc(Cl)cc1 +O=C(O)Cc1csc(NC(=O)c2nc3ccccc3n(C3CC4CCC(C3)N4C3CCCCCCC3)c2=O)n1 +COc1ccc(C(=O)Nc2ccccc2C(=O)NN=Cc2ccccn2)cc1OC +CC(Sc1cc(-c2ccc(C(=O)N(C)C)cc2)cnc1N)c1c(Cl)ccc(F)c1Cl +CC(C)Oc1ccc(N=c2[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +CC(=O)c1ccc2c(c1)C(NC(=O)c1ccsc1Cl)C(O)C(C)(C)O2 +O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(O)(c3cncs3)CC2)C1 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2CC(=O)NCC2CCOCC2)cc1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1-n1cc(-c2cncc(NC(C)(C)C)c2)nn1 +Oc1cc(C2=NCCN2)ccc1-c1cn(-c2cccc(C3=NCCN3)c2)nn1 +COc1ccc(N(C)c2nc(C)nc3c2C(C)CC3)cc1 +O=c1[nH]nc2c(NCCCc3cccnc3)cc(Cl)cn12 +CCc1c(C)sc2c1C(N1CCN(C)CC1)=Nc1cc(F)ccc1N2 +COC(=O)CN1CCCCC(NC(=O)C(CC(=O)NO)CC(C)C)C1=O +O=C(Nc1nn[nH]n1)c1cnc(N2CCOCC2)nc1OC1CCCCCC1 +CCN=CC1=Cc2c(cc3c(c2OC)OCO3)C(c2cc(OC)c(OC)c(OC)c2)C1C(=O)OC +CN1CCN(Cc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2N)CC1 +CCCc1nc2ccc(C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CCCCC(=O)O)cc1 +CCCc1c[nH]c(C2Cc3ccccc3N2C(=O)C(N)CC)n1 +O=C1C(C(O)c2ccc3c(c2)OCCO3)CCCN1CC=Cc1ccccc1 +CN1CCN(C(=O)c2ccc(N3CCc4c(-c5cnc(N)nc5)nc(N5CCOCC5)nc43)cn2)CC1 +CCN(C(=O)Nc1ccc(N(C)C)cc1)C1Cc2ccc(SC(C)(C)C(=O)O)cc2C1 +NS(=O)(=O)c1cc(-c2csc(C(=O)NC3CCN(C(=O)OCc4ccccc4)CC3)n2)ccc1Cl +COc1cc(OC)c2nnc3c(C)nc(-c4ccccc4C(F)(F)F)n3c2c1 +CC(C)CC(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)C2CCNCC2)CC1 +CC(C)CCn1c(=O)n(C(=O)NC(C(N)=O)C(C)(C)C)c2ccccc21 +COc1cc(C(=O)N2CC(C)(CC(C)O)OCC2C)cc2nc(NC(CF)c3cccc(Cl)c3)oc12 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cccc(O)c1O +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2cc(C(F)(F)F)ccc2F)c1 +CCOP(=O)(OCC)C(C)(C)[N+]([O-])=Cc1ccccc1C(F)(F)F +CCC(C)c1c(Cc2c(F)cccc2Cl)nc(SCC(=O)c2ccc(F)cc2)[nH]c1=O +O=C1N(Cc2ccc3ccccc3c2)C(Cc2ccccc2)C(O)C(C(F)Cc2ccccc2)N1Cc1ccc2ccccc2c1 +Cc1cc(C2OC(CO)C(O)C(O)C2O)sc1Cc1ccc(Cl)cc1 +CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(-c2cnccn2)cc1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nnc(Nc2cccc(OCc3ccccn3)c2)o1 +O=P(O)(O)C(Nc1ccccc1)c1cccc2nc(O)c(O)nc12 +CN1CCN(c2ccc(C3Oc4ccc(O)cc4SC3c3ccc(O)cc3)cc2)CC1 +N=C(N)c1cccc(Oc2ccc3c4ccccc4n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)c1 +Cc1ccc(N2CN3C(=N2)C(=O)Nc2ccccc23)cc1 +O=C(NCCCO)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 +Cc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(-c3ccc(-c4ccccc4)cc3)cc12 +CN(C)C(=O)OC1CC2CC(NCC(=O)N3CCCC3C#N)CC2C1 +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3cc(C#N)c(C)cc3Cl)ccnc21 +CNC(C)C(=O)NC1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2OC12CCOCC2 +Cc1c(C(=O)NCCCN2CCCC2)sc2ncnc(Nc3ccc(F)cc3OC(C)CF)c12 +Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(Cl)cc1 +CN(CC(CCN1CCC(O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +C=CCN1CCN(C(c2ccccc2)c2ccc(C(=O)N(CCC)CCC)cc2)CC1 +Cc1c(Cl)cccc1N1CCN(CCCNC(=O)c2nc(C)n(-c3ccc4c(c3)OCCO4)c2C)CC1 +Cc1c2cccc-2c(N(C)C)cc2c1[nH]c1ccccc12 +C=CCCN1CCC(COc2nc3ccsc3n3cccc23)CC1 +Cc1cncc(-c2cc(Nc3nn(C)cc3Cl)nc3[nH]cc(C#N)c23)c1 +O=c1cc(-c2ccccc2)oc2cc(OCCCCCN3CCC(O)CC3)ccc12 +O=C1OCC2C1C=C1CCCCC1C2C=Cc1ccc2ccccc2n1 +CC(=O)NC(Cc1ccc(F)c(F)c1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +CC1=CC(C)(C)Nc2ccc3c(c21)C(C1C=CCCC1)Oc1c(F)cc(F)cc1-3 +COC(=O)C1CCN(c2cc(-c3c(N)nn4cccnc34)ncn2)C1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCC(=O)NCc3ccco3)[nH]c3ccc(Cl)cc23)c1 +CCCCc1ccc(C(=O)N(CCc2ccccc2)C(CC)c2nc3ccccc3c(=O)n2-c2ccccc2OC)cc1 +C=CC(=O)Nc1cccc(Sc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2Cl)c1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2ccnc2C1 +CC1CN(CC(Cc2ccccc2)C(=O)NC(CCCCN)C(=O)O)CCC1(C)c1cccc(O)c1 +O=C(NC1CCCC1OCc1ccccc1)C1CCN(c2nc3cc(Cl)ccc3o2)CC1 +COC1CCC2(CC1)Cc1ccc(-c3cc(Cl)cc(Cl)c3)cc1C21N=C(N)N(C)C1=O +Cc1cc(C=CC(=O)O)cc(C)c1NC(=O)c1cccc(NC(=N)N)c1 +[H]C([H])(NC(=O)c1nc(N)nc2c(OC)cccc12)c1cccc(C([H])([H])c2cncc(OCCOC)c2)n1 +NC(CC(=O)NC1(c2cccc(-c3nccs3)c2)CCS(=O)(=O)CC1)Cc1ccccc1F +CC(C)(C)c1cc(NC(=O)C2CCCN2C(=O)N2CCS(=O)(=O)CC2)no1 +CC(C)(CO)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 +CC1CN(Cc2c[nH]nc2-c2ccc3c(c2)CNC(=O)O3)CCN1c1ccc(C(F)(F)F)cc1 +COc1ccc(Cn2nnc(C(=O)NCCCCCN3CCN(c4ccccc4OC)CC3)c2C)cc1 +COC1C(=O)N2C(C(=O)OC(C)(C)C)=C(COC(=O)NC(Cc3ccccc3)C(=O)O)CS(=O)(=O)C12 +COc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1F +CN(C(=O)Cn1c(=O)n2c3c(cc(-c4ccccc4)cc31)CCC2)c1cccc(Cl)c1 +COc1ccc(-c2nc3c(c(Nc4cc(F)c(CC(=O)O)cc4F)n2)S(=O)(=O)CCC3)cc1F +CC(C)(C)OC(=O)N1CCN(C(=S)SCc2cn(Cc3cc(=O)oc4cc(O)ccc34)nn2)CC1 +Cc1nc(-c2cnccn2)sc1C(=O)Nc1ccc(C2CNCCO2)cc1 +O=C(c1ccccc1)N1CCN(CC(O)COCc2ccccc2)CC1 +Cc1nc(-c2cn3c(n2)-c2ccc(N4CCC4C4CCN(C)CC4)cc2OCC3)n(C(C)C)n1 +Cc1cc(Cc2ccc(Cl)c(Oc3ccccc3)c2)n[nH]c1=O +CCCNC1=NC(=O)C(=C2CCNC(=O)c3[nH]c(-c4ccccc4)cc32)N1 +CN(CCC(Oc1ccc(-c2ccccc2)cc1)c1ccccc1)CC(=O)O +CC(C)NC(=O)c1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12 +O=C(NCc1cncnc1)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +CC(=O)Nc1nc2ccc(-c3ccnc(Sc4ccc(F)cc4)n3)cc2s1 +N=C(N)c1cccc(Oc2ccc(NC(=O)Nc3ccccc3)c(Oc3cccc(C(=N)N)c3)n2)c1 +COc1cc(OCc2csc(C3(NC(=O)CN(C)C)CCOCC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CN(C(=O)Cn1c(=O)oc2ccc(-c3ccccc3)cc21)c1ccncc1 +CCC(C)(CC)NC1=NCCNC(c2ccc(F)cc2)=C1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC4CC4)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +COc1ccc(Oc2c(Cl)cnn(Cc3c(OC)ccc4ccccc34)c2=O)cc1 +N#Cc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 +CC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCCC2C(O)c1ccsc1 +CCc1coc(-c2ccc(OC)c3nc(C(F)(F)F)ccc23)n1 +CCN(C(=O)c1ccc(CO[N+](=O)[O-])cc1)C1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +O=c1ccn(-c2cc(-c3ccc(Cl)c(Cl)c3)ccn2)cc1O +O=C1CCc2c(Oc3ccc4c(c3)C3C(O4)C3c3nc4ccc(-c5ccccc5)cc4[nH]3)ccnc2N1 +CCCCCn1c(C)c(C(=O)c2ccc(CC)c3ccccc23)c2ccccc21 +CCN(C)C(=O)c1cnn(C)c1C(=O)Nc1ccc2nc(N(CC)CC)nn2c1 +CCc1ccc(C(C)=NNC(=O)CNC(=O)C=Cc2ccco2)cc1 +CCOC(=O)N1C2CCC1CC(O)(C#Cc1cccc(C)c1)C2 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+CCCNC(=O)c1c(NC(=O)c2c(F)cccc2C(F)(F)F)sc2c1CCOC2 +O=S(=O)(Nc1cc(Cl)ccc1Cn1ccnn1)c1csc2ccccc12 +CN(c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)C=Cc3ccc(Cl)s3)C2=O)nc1)S(C)(=O)=O +Cc1ccc(F)c(CNC(=O)Cc2c(C)n[nH]c2C)c1Cl +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCC(N2CCCC2)CC1 +Cc1cccc(Nc2cc(NC3CCCCC3N)nnc2C(N)=O)n1 +COC1CC(C(C)C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +Cc1c(C=CN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(c1ccc2[nH]ccc2c1)n1nnc2c(N)nc(C3CC3)nc21 +O=C(OCC(COC(=O)c1cc(O)c(O)c(Br)c1)OC(=O)c1cc(O)c(O)c(Br)c1)c1cc(O)c(O)c(Br)c1 +CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OC)c(F)c1 +CN1c2cc3c(cc2C2CCCC(C)(C)C21)c(C(F)(F)F)cc(=O)n3C +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CC(C)(C)C=C(C)C +Cn1nnnc1-c1cccc(NC(=O)NC2CCCCC2CNCCCc2ccc(F)cc2)c1 +CC(=O)Nc1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(C)c(COc3cccc4ccc(C)nc34)c2C)cn1 +COc1ncc(-c2cc(OC(C)C3CNC(=O)C3)c3cccnc3c2)cc1F +N=C(N)Nc1cccc(C(=O)Nc2ccc(C=CC(=O)O)c(C(=O)O)c2)c1 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+CC1(C)CC=C(c2cc(C3(O)CCCC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +O=S(=O)(Nc1ccc2ccn(CCN3CCCC3)c2c1)c1c(Cl)nc2sccn12 +NC1=CC(=O)c2ccc(-c3[nH]c(CO)cc4c5ccccc5nc3-4)nc2C1=O +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1 +COc1cccc(C=Cc2nnc(NC(=O)c3cc(OC)c(OC)c(OC)c3Br)s2)c1 +Cc1ccc2[nH]c(C(=O)NCCCCCCC(=O)NO)cc2c1 +CC(O)C1CCC2(O)C3CCC4CC(OCC5OC(OCC6OC(O)CC(O)C6O)CC(O)C5O)CCC4(C)C3CCC12C +CS(=O)(=O)c1ccc(-c2c(-c3ccccc3)sc3nncn23)cc1 +Cc1ncc(C#Cc2c(C)ncnc2N2CCOCC2)cc1NS(=O)(=O)c1cnoc1C +[C-]#[N+]C(C)(C)CC1CC(C)C2CCC(C)([N+]#[C-])C3CCC(=C)C1C23 +COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)C2=NCCC2)c1Cl +CC12C=CCC3(C)C(=O)OC(C13)C1OC13COC(=O)C=C23 +C=C(C)C1CCC2(NC(=O)NCCOCCO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +O=C(c1cc(-n2ccc3ccccc32)c(O)cc1O)N1CCc2sccc2C1 +CC(C)(CN)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +Cc1nc(C(C)(C)NC(=O)c2cccc(-c3ccc(Cl)c(F)c3)n2)no1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC)C(C(=O)O)c2ccccc2Cl)cc1 +CCCCCCCCCCCCn1nnc(C(Cc2ccccc2)S(=O)(=O)Nc2c(C(C)C)cccc2C(C)C)n1 +CNC(=O)CN1N=C(c2ccccc2)C2(CCN(C3CCC4CCCCC4C3)CC2)C1=O +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(C#N)c(-c2cnc3ccccn23)n1 +COc1ccc(S(=O)(=O)N(CC(=O)O)C(C(=O)NO)C(C)C)cc1 +CC(c1ccccc1)N1CCC2(CC1)OC(CF)c1ccccc12 +c1ccc2c(c1)CC2CCCN1CCN(c2cccc3c2OCCO3)CC1 +CCCOc1ccc(F)c(-c2cccc(C(=O)Nc3cnccc3C3CCC(O)C(N)C3)n2)c1 +O=C(Nc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(C(O)C(F)F)cc2)c1)c1ccc(Cl)cc1 +O=C(Nc1cccc(Oc2cccc3[nH]c(=O)[nH]c23)c1)c1ccc(F)c(OC(F)(F)F)c1 +NC1CCCCCCC(C(=O)NCc2ccccc2CC(=O)O)NC(=O)C(Cc2ccc(O)cc2)NC1=O +COc1cnn(CC(=O)C2CCC3C4CCC5CC(C)(O)CCC5C4CCC23C)c1 +O=c1cc(-c2ccc(O)c(O)c2)oc2c1ccc1ccccc12 +O=C(NC(Cc1ccc(-c2ccccc2)cc1)C(=O)O)C(CS)Cc1ccccc1 +CC(C)(C)c1ccc(-c2cnnc(Nc3ccc4c(c3)OCCO4)c2)cc1 +Cc1cc(C(N)=O)c2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)n2c1 +COc1cc2c3c(-c4cccc(O)c4)c[nH]c(=O)c3n(C)c2cc1OC +Fc1cc(F)c(CN2CCN(c3nc4ccncc4nc3Nc3cccnc3)CC2)cc1F +Cc1ccc(OCC(=O)Nc2ccc(-c3nc4cc(C)cc(C)c4o3)cc2)cc1 +Cc1cc(-c2cc(F)cc(Cl)c2)ncc1C1CCCN1C(=O)c1cnccn1 +CN(C)C(=O)c1ccc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1Cl +CCC1=C2C3C=C(C)CC2(NC1)c1ccc(O)nc1C3 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCc3cccnc3)[nH]c3ccc(Cl)cc23)c1 +Cc1ccc(SCc2noc(-c3c(C)noc3C)n2)cc1 +OC12C3C4CC5C6C4C1C6C(C53)N2Cc1cccc(Cl)c1 +CCOC(=O)c1cn2c3c(nc(O)c2n1)-c1ccc(NC(=O)NC)cc1C3 +CC(C)CS(=O)(=O)Nc1ccc(CN2CCC(CNC(=O)c3cccc4c3OCCO4)CC2)cc1 +NS(=O)(=O)c1c(F)cccc1NS(=O)(=O)C=Cc1ccc(-c2cc3ccccc3o2)cc1 +NS(=O)(=O)c1cccc2c1C(=O)C=C(Nc1ccccc1N1CCNCC1)C2=O +CN(Cc1ccc2c(c1)OCO2)C1C2C3CC4C5C3CC2C5C41 +COc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2c1 +CN(C)S(=O)(=O)Oc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +NC1CCN(c2nc(Nc3cc(C4CC4)[nH]n3)c3occc3n2)CC1 +O=C(NCc1ccccc1)c1ccc2cc(-c3n[nH]c4ccccc34)[nH]c2c1 +CN(C)C(=O)c1ccc(C(O)(c2ccccc2)c2ccc(C(=O)NCCCCCCC(=O)NO)cc2)cc1 +CC(CCc1ccc(-c2ccc3c(c2)C(=O)NC3)cc1)(C(=O)NO)S(C)(=O)=O +CNC(=O)C(NC(=O)c1ccc(-c2ccc(Cl)cn2)o1)C1CCCCC1 +CC(C(=O)Nc1cc(C2CC2)[nH]n1)c1ccc(N2CC(=O)NC2=O)cc1 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+Cc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1 +CCN1CCCC1CNc1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 +O=C1CC(C(=O)Nc2cc(-c3cc(F)cc(COCC(F)(F)F)c3)n(-c3cccc(F)c3)n2)CN1 +CCOCC=Cc1ccc(-c2nc(-c3ccc(NC(C)C)cc3)c(-c3ccc(NC(C)C)cc3)[nH]2)cc1 +CC(C)C(NS(=O)(=O)c1cccc(Br)c1)C1=CC(=O)c2c(O)ccc(O)c2C1=O +COC(=O)NC(C(=O)NN(CCCC(O)(Cc1ccccc1)C(=O)NC1c2ccccc2CC1O)CC(C)C)C(C)(C)C +Cc1[nH]c(C(=O)NC2CCN(c3ncc(C(=O)O)s3)CC2Cl)c(Cl)c1Cl +CC(=O)NCCCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1ccc(F)cc1F +O=C(NO)c1ccc(CN2c3ccccc3NC(=O)C2CCc2ccccc2)cc1 +O=C(CN1CCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)[nH]c23)c2sc3ccccc3c12 +CC1CCN(C(=O)c2sc(-c3ccc(S(C)(=O)=O)c([N+](=O)[O-])c3)nc2C(F)(F)F)CC1 +N#Cc1ccnc(N2CCC(S(=O)(=O)c3ccccc3C(F)(F)F)C2)n1 +COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +CC(C)c1cccc(NC(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +O=C(O)CCSC(CCc1ccccc1-c1nc[nH]n1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 +CCn1cc(-c2ccc3cnc(Nc4ccc(-c5cnc(C)n5C)cc4OC)cc3c2)cn1 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+COc1cccc(-c2cccc(CN3CCN(c4ncccn4)CC3)c2)c1 +Cc1ncc(C(=O)NCc2ccccc2N2CCN(C)CC2)cc1NC(=O)c1cnn2cc(-c3ccnn3C)ccc12 +O=C1c2ccc(Nc3ccc(F)cc3F)cc2CCc2ccc(OC3CCOCC3)cc21 +COc1ccc(Nc2nc(N3CCC(C(=O)Nc4ccc(C(=O)O)cc4)C3)nc3scnc23)cc1OC +O=[N+]([O-])c1ccc(-c2nn(-c3ccc(Br)cc3)cc2C=NNC(=S)Nc2ccccc2)cc1 +CC1CN(c2ccc(C(=O)Nc3ccccc3N)cn2)CCN1C(=O)NCCc1ccccc1 +O=C1CCC(CCN2CC(N3CCNCC3)C2)(c2ccc(Cl)c(Cl)c2)CN1CC1CC1 +CCc1[nH]cc2c1NC1=C(C(=O)CNC1)C2c1cccc(Sc2nc3ccccc3[nH]2)c1 +CN(C)CCN(C)C(=O)c1ccc2c(c1)-c1nc(N)nc(-c3ccccc3)c1C2=O +O=C(NC1CCN(Cc2cc3c(cc2Cl)OCO3)CC1)c1cc(=O)c2ccc(F)cc2o1 +COc1ccc2[nH]c(-c3cc[se]c3)cc(=O)c2c1O +COCCN1CC(=O)Nc2ncc(-c3ccc(-c4nc[nH]n4)nc3C)nc21 +CCCCCCCCc1cc(Cc2ccc(F)cc2)c(C=C2N=C(c3ccc[nH]3)C=C2OC)[nH]1 +O=C(C=Cc1cnccc1-c1cnn(C2CC2)c1)Nc1ccc(CN2CC(F)(F)C2)cc1 +CN1C(=O)N(CCN2CCOCC2)CC1C(=O)NCc1cccc(C(F)(F)F)c1Cl +CCc1cc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c2cc(OCC(F)(F)F)ccc2n1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)N1CSCC1C(=O)NC(C=O)CCCN=C(N)N 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+c1cc(-c2n[nH]c3cnc(-c4cncs4)cc23)nc(N2CCCCC2)c1 +O=c1[nH]c2ncc(-c3ccc(-n4cccn4)cc3)nc2n1CC1CCOCC1 +CCOC(O)=C1C(COCc2cc(O)nc(SC)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +N#CC1(c2ccccc2OC(F)(F)F)CCC(CNc2ncccc2NC(=O)CC(F)(F)F)CC1 +CCCCCCOC(=O)C(C)NP(=O)(OCC1OC(n2cc(F)c(=O)[nH]c2=O)CC1O)Oc1cccc2ccccc12 +Cn1c(=O)n(C2CCC(C(=O)OCc3ccccc3)CC2)c2c3nc(-c4cnc5ccccc5c4)ccc3ncc21 +Cc1nc2cc(-n3ncc(C(=O)c4cc5ccc(-c6cccs6)cc5[nH]4)c3N)ccc2[nH]1 +O=C(NO)C1CCCC1C(=O)Nc1ccc(OCc2ccncc2)cc1 +O=C1NCc2ccc(OCCCCN3CCN(c4cccc5ccccc45)CC3)c(F)c21 +CC(=O)Nc1cccc(Nc2ncnc(N3CCC(OCc4ccc(C(F)(F)F)cc4)CC3)n2)c1C +N#Cc1ccnc(N2CCC(S(=O)(=O)c3ccc(N4CCN5CCCC5C4)cc3Cl)C2)n1 +CCN1CCCC1CNC(=O)c1ccc(-c2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)s1 +NC(=O)c1ccc2sc(-c3c(NC4CCCNC4)nc(N4CCOCC4)[nH]c3=O)nc2c1 +CCCc1ccccc1Oc1ccc(-c2nc(-c3sc(CN4CC(C(=O)O)C4)cc3CC)no2)cc1 +CN1CCC(c2ccc(Cl)cc2)C(CC(=O)NC23CC4CC(CC(C4)C2)C3)C1 +COC(C)(C)CCn1nc(Nc2c(C)cc(F)cc2C)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21 +NC(=O)Nc1cccc2c1C(=O)c1c(C3CC3)n[nH]c1-2 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+CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4ccc5c(c4)CCC(N4CCOCC4)CC5)nc23)cc1 +COc1cc2ncc3c(c2cc1CCc1ccsc1)n(-c1ccc(C#N)cc1F)c(=O)n3C +Cc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(OCCc3ccccn3)nc1)CC2 +CC(O)C(O)c1cnc(N2CCN(C(=O)Nc3nc4ccc(F)cc4s3)C(C)C2)c(F)c1 +Cc1ccc(C(=O)Nc2ccon2)cc1Nc1nc(N)nc(NC2CCCC2)c1C#N +Cc1ccccc1N1CCc2c(C)nc3c(F)cccc3c21 +CCC(CC)OC1C=C(C(=O)O)CC(NCc2cccs2)C1NC(C)=O +O=S(=O)(Nc1nccs1)c1ccc(Nc2nncc3ccccc23)cc1 +CC1(C)Cc2cc3c(C(F)(F)F)cc(O)nc3cc2NC1(C)C +CCCCCCCCC(CC(=O)NO)C(=O)NC1CCCCN(CCOC)C1=O +C=CCCCCCCOc1ccc(C(=O)Nc2cccc3c(=O)cc(-c4nn[nH]n4)oc23)cc1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(C)c21 +Cc1c(C)n(Cc2cccc(C(=O)O)c2)c2ccc(C(=O)NC(C)c3cccc(C4CC4)c3)cc12 +CN1CCC(n2cnc(-c3ccc(F)cc3)c2-c2ccnc(Nc3ccncc3)n2)CC1 +CC#CC(=O)N1CCC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)CC1 +c1cc2cc(CN3CCCNCCNCCCNCC3)ccc2cc1CN1CCCNCCNCCCNCC1 +N#Cc1cc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)ccc1F +O=C(O)C1=CCCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)C1 +NC(=O)Nc1cc(-c2cccc(F)c2F)sc1C(=O)NC1CCCNC1 +O=C(NCCCCCCS)c1cc(-c2ccc(F)cc2)n(CCCCO)n1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C4CC4)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +COc1cccc(C2OC(CC(=O)NCCCC(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC +COc1cc(C(=O)O)ccc1Cc1cn(CC2CC2)c2ccc(NC(=O)OC3CCCC3)cc12 +CC(Nc1ncnc2c(C(N)=O)cccc12)C1=CC(NC(=O)C2(C(F)(F)F)CCC2)=CCC1 +Cc1ncc(C)n2nc(-c3ccn4cc(-c5cccc(C6CC6)c5)nc4c3)nc12 +Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc21 +CC(C)OC(=O)c1nc2ccc3ncnc(Nc4ccc5c(c4)OCO5)c3c2s1 +O=C(c1cc(-c2ccccc2)nc(-c2ccccc2)c1)N1CCN(C2CCN(C(=O)N3CCCCC3)CC2)CC1 +N#Cc1cccc(-n2nc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)c(C(=O)O)c2-c2ccccc2)c1 +CS(=O)(=O)N1CCN(CCCCOc2cccc(NC(=O)CC34CC5CC(CC(C5)C3)C4)c2)CC1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Nc3ccc(N4CCOCC4)cc3)n2)n[nH]1 +O=C(C=Cc1ccccc1)OC1C(O)C(CO)OC(Oc2c(O)cc3oc4cc(O)c(O)cc4c(=O)c3c2O)C1O +CCC(=O)Nc1cc(-c2ccccc2F)nc(-c2ccccc2F)n1 +CC(C)=CCCC(C)=CCc1c(O)ccc(C2COc3cc(O)cc(O)c3C2=O)c1O +COc1ncc(-c2cnc3[nH]cc(C(=O)c4c(F)ccc(NS(=O)(=O)c5cccc(F)c5)c4F)c3c2)cn1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(Nc2ncc(C(F)(F)F)cc2Cl)c1 +O=C1OC(Cn2cc[n+]3ccccc23)CC1(c1ccccc1)c1ccccc1 +COc1ccc(C(O)CC2NCCc3cc(OC)c(OC)cc32)cc1 +O=C(c1ccc(-c2cccs2)cc1)N1CCn2c(nnc2-c2ccccn2)C1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ccncn3)cs2)CO1 +Cc1cc(Nc2nc(NC3CCCCC3N)nnc2C(N)=O)cc2cccnc12 +CNC(=O)OCCc1ccc(Cl)c(CN(C(=O)C2CNCCC2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1 +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)nc1 +Cc1cc(-c2c(F)cc3c4nn(C5CCOCC5)c(=O)c-4cn(C4CC4)c3c2F)cc(C)n1 +CCOC(=O)c1ccc(CCc2nc3cccc4c3n2CCNC4=O)cc1 +CC(C)c1ccccc1Sc1ccc(C2CC2C(=O)N2CCC(C(=O)O)CC2)c(Cl)c1Cl +Cc1cc(C)nc(N2CC3CN(C(=O)c4cc(Cl)ccc4C)CC3C2)n1 +CC1(C)Oc2cc(C34CC5CC(CC(C#N)(C5)C3)C4)cc(O)c2C2CC(O)CCC21 +CCCN(CCC1CCC(NC(=O)c2ccc(-n3cncn3)cc2)CC1)C1CCc2nc(N)sc2C1 +CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(S(=O)(=O)Nc4ccc(OCCCc5ccccc5)cc4F)cc3C2)cc1 +O=C(Nc1nc2ccc(O)cc2s1)c1cccc(O)c1F +Cc1ccc(S(=O)(=O)N2CCSC2C(=O)NC(C=O)Cc2ccccc2)cc1 +COC(C(=O)NC1CCC(OC(=O)c2ccccc2)CNC1=O)C(O)C(O)C(O)C=CC(C)(C)C 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+CC(C)NC(=O)c1cn(-c2cccc(-c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1=O +O=C(NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1)C1CCN1 +CC(=O)N(CCCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)CC1CCCCC1 +O=C1CC(C(=O)Nc2cc(-c3cccc(C(F)(F)F)c3)n(-c3ccccc3F)n2)CN1 +CNCc1cc(-c2ccc3c(N)cc4n[nH]c(=O)n4c3c2)cs1 +CCOC(=O)c1c(C#N)csc1NC(=O)Cc1ccc(OC)cc1 +CNC(=O)C(NC(=O)c1ccc(-c2ccc(NC(=O)c3cc(C)c(C)o3)cc2)o1)C1CCCCC1 +CCCC(=O)N1CCC(c2ccc(Cl)cc2)C1C(=O)N1CCN(c2ccc(C)cc2C(N)C(C)C)CC1 +COCCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2c1)c1ccccc1 +COc1cc(OCC(=O)Nc2ccc(Br)cc2)ccc1-c1cc2c([nH]1)c(=O)n(C)c(=O)n2C +CCOC(=O)C=CC(CC1CCCNC1=O)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(C4CCN(C)CC4)nc3)NC(=O)NC1=O)C2 +CN1CCN(c2cccc(N(Cc3ccccc3)S(=O)(=O)c3ccc4ccccc4c3)c2)CC1 +CN(C)CC1CCn2c(c(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c3ccccc32)C1 +Cc1cnc2nc(SCc3cccc(F)c3F)nc(NC(C)CO)c2n1 +O=C1NC(=O)C(c2ccc(Cl)cc2)=C1Nc1cc(Cl)c(O)c(Cl)c1 +CC=CCNc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CCNC(=O)C1OC(n2cnc3c(N)nc(NCCN4CCN(c5ccccc5F)CC4)nc32)C(O)C1O +CC(C)(C)c1ccccc1N1CCN(C(=O)C(O)CO)CC1 +Cc1c(-c2ccc(Cl)cc2)nc(O)n1C1CCN(Cc2ccccc2)CC1 +OCC1OC(n2cnc3c(SCc4ccc(Cl)c(Cl)c4)ncnc32)C(O)C1O +Cc1cc(OCc2cc(-c3ccc(Cl)cc3)on2)cc2scc(CC(=O)O)c12 +Cc1ccc(C(=C(CCCO)c2cccc(F)c2)c2ccc(OCCN(C)C)cc2)cc1 +CN(C)Cc1ccc(-c2cc3c(-c4cnn(C)c4)c(Cl)cnc3[nH]2)cc1 +Nc1nc(N2CC3CC2CN3)c2oc3ccc(Cl)cc3c2n1 +CCOC(=O)C(Cc1cc2ccnc(N)c2cc1OCCOC)N1CCC(NS(=O)(=O)c2cnc(N(C)C)s2)C1=O +CC(C)S(=O)(=O)n1c(N)nc2ccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)cc21 +CC1=NN(C(=O)c2ccccc2O)C(=O)C1=Cc1cccc(O)c1 +COc1ccc(-c2cc(-c3c[nH]c4ccccc34)nc(N)c2C#N)c(OC)c1OC +NC(=O)c1nnc(NC2CCOCC2N)nc1Nc1cccc2c1ccn2C1CCC1 +CCC(c1c(Cl)c(Cl)cc2nc(O)c(O)nc12)n1ccnn1 +COC1Cc2cc(-c3ccc(C)cc3)sc2C2(CCN(Cc3ccccc3)CC2)O1 +Cc1cc(-c2ccccc2)cc(C)[n+]1CC(=O)Nc1nnc(S(N)(=O)=O)s1 +CCN1C(=O)c2nc(-c3ccc(F)c(C#N)c3)n(Cc3ccc(F)c(F)c3)c2N2CC(C(C)C)N=C12 +CN1C(=O)c2ccc(F)cc2C2(CC(=O)NC2=O)C1=O +CC(C)(F)CC(NC(c1ccc(-c2ccc(C3(C(N)=O)CC3)cc2F)cc1)C(F)F)C(=O)NC1(C#N)CC1 +O=C(NCCN1CCOCC1)c1cccc(-n2ncc3cc(Nc4ccccc4)cnc32)c1 +COC(=O)C(NCc1cc2ccccc2c(-c2c(O)c(CNC(C(=O)OC)C(C)C)cc3ccccc23)c1O)C(C)C +CCOC(=O)C(=O)N1c2ccc(C)cc2-c2c(ssc2=S)C1(C)C +COc1cc(Cl)c(Cc2ncc(-c3cccs3)s2)cc1C1OC(CO)C(O)C(O)C1O +COC(=O)N1CCN(c2ccc(NC(=O)c3nc(-c4ccccc4)oc3C(F)(F)F)cc2)CC1 +CCS(=O)(=O)c1ccc2[nH]c(-c3cccc(-c4ccccc4)c3Cl)nc2c1 +Nc1noc2cccc(-c3ccc(NC(=O)Nc4cccc([N+](=O)[O-])c4)cc3)c12 +O=C(NCCCF)c1c[nH]c2ccc(Cc3ccccc3)cc2c1=O +CCOC(=O)C1=C(CN2CCOCC2C(=O)OC(C)C)NC(c2nccs2)=NC1c1ccc(F)cc1Br +N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1ccc(F)c(F)c1 +CN(C)CCn1c(Cn2nc3ccccc3n2)nc2ccccc21 +Cc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccccc2I)c(C)c1 +CC=C1CN(C(=O)C(CCCCNC(=N)N)NC(=O)c2ccccc2)C(C(=O)NC(CC(C)C)C(=O)O)C1C +CCCCCS(=O)(=O)NC(=O)C=Cc1ccc(OCCOC2CC2)cc1Oc1ncc(C(F)(F)F)cc1Cl +CCCCCCCCCOC(=O)C1CN(CC)CC=C1c1ccccc1 +CC(=O)c1ccc(C=Cc2cc3c(c(=O)n(C)c(=O)n3C)n2C)cc1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC2(c3ccccc3)CCCC2)c1 +Cc1cc(COc2ccc(S(=O)(=O)N(C)C3COCC3C(=O)NO)cc2)c2ccccc2n1 +CC(C)Cc1ccc(C(C)c2nc3cc(OCc4ccccc4C#N)ccc3n2Cc2ccccc2Cl)cc1 +COc1ccc(CC(=O)NNC(=O)Cn2c(C)nc3ccccc32)cc1 +Cc1cc(S(C)(=O)=NC#N)ccc1CNC(=O)c1cn(C(C)C)c(C)c(-c2cccc(C(F)F)c2)c1=O +CC1(C)CC(NC(=O)CO)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2O1 +O=C(CCCCNC(=O)c1csc(-c2cscn2)n1)NO +N#Cc1ccc(Oc2ccc3c(Cn4ccnc4)cc(=O)oc3c2)cc1 +Cc1ccccc1-c1c(C#N)c(N)nc2sc(C#N)c(N)c12 +Cc1ccc(Nc2ncnn3cc(C(=O)NCCCN4CCOCC4)c(C)c23)cc1O +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)c5ccon5)C4)c3C2)cc1C +Cc1cccc(NC(=O)Nc2ccc(C#Cc3ccc4nc(N)cn4n3)cc2)c1 +CN(CC(CCN1CCC2(CC1)CS(=O)(=O)c1ccccc12)c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccccc1 +O=C(CSc1nnc(Nc2ccccc2)s1)NN=Cc1ccc(-c2ccc(Cl)cc2)o1 +CNC(=O)C1CSc2ccccc2NC(=O)COC(C(=O)NO)C(CC(C)C)C(=O)N1 +COc1cc(OC)cc(N(CCCN2CCC(S(C)(=O)=O)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CSc1nn2c(C)c(Cl)c(C)nc2c1S(=O)(=O)c1ccccc1 +NC1CN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1c1ccc(F)cc1 +CC(C)(C)c1ccc2c(c1)C1OCCCC1C(c1ccc(Cl)s1)N2 +COCCN(C(=O)c1cnc(-c2ccccc2C)cn1)c1ccc(OC)nc1 +CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CC3CCC(C3)C2)cc1 +O=C(O)c1cc(-c2ccc(CNS(=O)(=O)c3ccc(OC(F)(F)F)cc3)cc2)n(-c2ccc(Cl)c(Cl)c2)n1 +CN(C)c1ccc(-c2cnc3cc(OCCF)ccc3n2)cc1 +Fc1ccc(N2CCN(CCC(Oc3ccc(C(F)(F)F)cc3)c3ccccc3)CC2)cc1 +Cc1nn(Cc2ccccc2)c(Cl)c1C(=O)NCCc1ccccc1 +CCC(CC)Sc1nc2cc(Cl)c(N3CCN(CCO)CC3)cc2[nH]1 +Cn1cc(C(C(=O)Nc2ccc3ccccc3c2)P(=O)(O)O)c2cc(Cl)ccc21 +CC(C)C(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2c1)c1ccccc1 +CN1C(=O)NC(=O)C12Cc1ccc(NC(=O)Cn3c(=O)n(-c4ncccn4)c4ccccc43)cc1C2 +Cc1nnc2sc(C(=O)NC3CN(c4nc5cccnc5s4)C3)c(N)c2c1C +Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccccc4)cc3=O)cn12 +Cn1cc(C2=C(c3cccnc3)C(=O)NC2=O)c2ccccc21 +COC(=O)C1CC(NS(C)(=O)=O)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2nc(C(F)(F)F)co2)CC1c1ccc(C(F)(F)F)s1 +CCn1nc(-c2ccc(Cl)cc2)cc1C1CCN(CCc2ccccc2)CC1 +Cc1cccc(-c2nn(CC(=O)Nc3cccc(C#N)c3)cc2-c2ccc3ncnn3c2)n1 +O=C(CCCNC(=O)C(Cc1ccc(O)c(Br)c1)=NO)NO +Cc1cncc(Oc2ccc(Cn3cc(C(=O)NCc4c(C)cc(N)nc4C)cn3)cc2)n1 +CCN(CC)C(=O)C1CNC(C(=O)N2CCCC2C#N)C1 +CCNC(=O)C1OC(n2cnc3c(NCCCCCCNS(=O)(=O)c4cccc5c(N(C)C)cccc45)ncnc32)C(C)C1C +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2c(F)cccc2F)C1 +CC(=O)OC1OCCC1NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)c1ccc2c(c1)Nc1ccccc1S2 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1ccc(OC(F)F)c(F)c1 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)c2cc1OCCOC +Cc1cc(=O)oc2cc(NC(=O)c3ccccc3Cl)ccc12 +O=C(COc1ccc(Cl)cc1)Nc1nnc(-c2ccc3c(c2)CCCC3)o1 +Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cc(F)cc(Cl)c2)C(N)CC3)c1 +Clc1cccc(Nc2nccc(-c3cccc(N4CCNCC4)c3)n2)c1 +Cc1ccc(Sc2ccccc2CSC(=N)N)c(CSC(=N)N)c1 +O=C(CCCCCONC(=O)Nc1cccc2cccnc12)NO +CNc1nc(NCc2ccc(OC(F)(F)F)cc2)cc(-c2ccccn2)n1 +N#Cc1ccc(-n2nc(C(N)=O)c3ccc4[nH]ncc4c32)cc1 +Cc1cc(C#N)cc(NC(C)c2cc(C(=O)N(C)C)cc3c(=O)cc(N4CCOCC4)oc23)c1 +COc1cc(NC(=O)C2CC(F)CN2C(=O)Nc2cn(C(N)=O)c3ccccc23)ccn1 +Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccco4)C3c3ccc(C)o3)sc2c1 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+CN(C)CC1CCN(C(=O)Nc2nc3c(s2)-c2nc(C(C)(C)C)ncc2CC3)C1C(N)=O +CC(O)CSc1nc2c(c(Nc3ccc4c(c3)N(C)CCC4(C)C)n1)CCN(c1ncccc1C(F)(F)F)CC2 +CN1Cc2c(C3CCN(CC(=O)O)CC3)[nH]c3nccc(c23)-c2cc(F)ccc21 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)c2cc1OCCN1CCCCC1 +CC(C)c1cccc2c3c(n(Cc4ccc(Cl)cc4)c12)C(CC(=O)O)CCC3 +CN1CCC(N(C)C(=O)C2CN(S(=O)(=O)c3cccs3)c3ccccc32)CC1 +FCCn1cc(-c2ccncc2)c(-c2ccc(OCc3ncccc3F)cc2)n1 +O=C(C=Cc1cccn(CC=Cc2cccc(C(F)(F)F)c2)c1=O)NO +C=CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21 +CSc1cnn2c(NCc3cccnc3)cc(-c3ccccc3)nc12 +CC(=O)N1CCC(c2nc(-c3cc4ccccc4[nH]3)c3c(N)nccn23)CC1 +CCCCN1C(=O)CC(C(=O)OC2CC3CCC(C2)N3C)c2ccccc21 +CSc1cc(C)nc(SC)c1NC(=O)N(Cc1ccc(Oc2ccc(F)cc2)cc1)Cc1c(C)cccc1C +Cc1cc(N)nc(CCc2cccc(C(CN)Cc3cc(C)cc(N)n3)n2)c1 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccn(O)c(=O)c2)cc1 +CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4cccnc4)ccc3Sc3ccc(N)cc3)ncnc2n1 +Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(F)c3)c12 +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(OC(=O)Cc2ccccc2Cl)c1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(NC(C)C)cc3OC)ncc2Cl)c1 +CCCC(=O)OC1=C(c2ccccc2)Sc2ccccc2-n2cccc21 +NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(NC(=O)c3c(F)c(F)cc(F)c3F)cc2)cc1 +CCC1(OC(=O)CCC(P(=O)(O)O)P(=O)(O)O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 +CC(C=NOCCN)=CC1CCC2(O)C3CCC4CC(O)CCC4(C)C3CCC12C +CC1CN(C)CCc2ccc(Nc3ncc(Cl)c(NC4C5C=CC(C5)C4C(N)=O)n3)cc21 +NC1CCC(Nc2cc(-c3cccc(NCC4CCCCC4)n3)c(Cl)cn2)CC1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccc2ccccc2c1 +Cc1[nH]c(C(=O)NC2CCN(c3nnco3)CC2)c(Cl)c1Cl +COc1cc(Cc2c(-c3ccc(NC(=O)CN4CCS(=O)(=O)CC4)cc3)sc3cc(O)ccc23)ccc1CN1CCCC1 +Cc1cc(COc2ccc(S(=O)(=O)C3(C(=O)NO)CCN(C=O)CC3)cc2)c2ccccc2n1 +COCCCC(=O)NCCN1CCCC1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O +COc1cccc(CC2(N)CCN(c3ncnc4[nH]ccc34)CC2)c1 +CCc1c(Sc2ccc3ccccc3c2)[nH]c2nc(N)nc(N)c12 +COc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1Br +Cc1sc(-c2cccc3ccccc23)cc1C(=O)N1CCC(CO)CC1 +CC1(O)CCC2CC1OOC2(C)CS(=O)(=O)c1ccc(F)cc1 +N=C(N)NCCCC1NC(CNC(=O)c2ccc3ccccc3c2)CCN(CC(c2ccccc2)c2ccccc2)C1=O +Cc1cc(C(=O)NCc2cc(Cl)ccc2-n2cnnn2)cc(C2CNCCC2CC(C)C)c1 +N#CC(Cc1ccc(-c2ccc3c(c2)CNC3=O)cc1F)NC(=O)C1NC2CC1C1CC21 +CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C +CCCCOC(=O)NS(=O)(=O)c1cc(CC(C)C)ccc1-c1ccc(C(=O)N(CC)CC)cc1 +CC1CN(CCc2ccccc2)CCC1(C)c1cccc(C(N)=O)c1 +CNC(=O)C12CC1C(n1cnc3c(NCc4cccc(Cl)c4)nc(I)nc31)C(O)C2O +O=c1[nH]c(CCCN2CC=C(c3ccccc3)CC2)nc2ccccc12 +O=C(O)Cc1ccc2c(c1)Cc1c-2nc(O)c2nc(C(=O)O)cn12 +CCCNC(C)Cc1ccc(OC)c(OCCc2ccccc2)c1 +CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)cn1C1CC2C1)CF +CCN1CCC(NC(=O)c2csc(NC(=O)c3ccc4cc5n(c4c3)C(C)CNC5=O)n2)CC1 +CCNc1cc(-c2nc(C(F)(F)F)nc3c(-n4cnc(-c5cnn(C)c5)c4)cccc23)ccc1C(N)=O +CC(C)CC(=O)OCC1(CO)CC(=CCC(CC(C)C)CC(C)C)C(=O)O1 +O=C(C1CC1)N1Cc2n[nH]c(=O)c3cccc4[nH]c(c2c43)C1 +CC(C)C1CCCC(COC(=O)N2CCN(CCO)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +Cn1cc(C(=O)Nc2cc(Cl)c(CC(=O)N3CC(O)CC3COC3CCC(C(=O)O)CC3)cc2Cl)c2ccccc21 +Cc1onc(-c2cc(F)ccc2F)c1COc1ccc(C(=O)NC(C)C)cn1 +O=C(c1ccccn1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NC(C)C(=O)O +OC1=C2C(=Nc3cc4c(cc3C2c2ccc3c(c2)OCO3)OCO4)CO1 +C=C(C)C12CC(C)C34OC(CCCCCCCCC)(OC1C3C1OC1(CO)C(O)C1(O)C(=O)C(C)=CC14)O2 +C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC +CCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O +COc1ccccc1-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1 +COc1ccc(C2CC(=O)N(c3cccc(NS(=O)(=O)c4cc(Br)c(Cl)s4)c3)C2)cc1OC1CCCC1 +CCN(CC)c1ccc2cc(C(=O)c3ccc(NS(=O)(=O)c4ccccc4)cc3)c(=O)oc2c1 +C(#Cc1ccc(C(N2CCOCC2)N2CCOCC2)cc1)c1ccccc1 +CC(=O)NCCc1c(C2CC2)nn2ccc3c(c12)CCO3 +CCCCCC(O)c1ccc(C2CCC(=O)C2CCCCCCC(=O)O)cc1 +COc1ccccc1-c1cn2c(-c3c(C)cc(C)cc3C)c(CN)c(C)nc2n1 +O=C(NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1)NC(Cn1cncn1)c1ccccc1 +O=c1[nH]c(N2CCOCC2)nc(NC2CNC2)c1-c1nc2ccccc2s1 +CCCCc1nc2c(N)nc3ccccc3c2n1Cc1cccc(CN)c1 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=S)N(C)C)CC2 +CCC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCCOC)c1=O +COc1ccc(CNC2CCC(C(=O)N3CCC(C(=O)N4CCCC4)(c4ccccc4)CC3)C(C)(C)C2)cc1 +c1cc2cc(-c3ccc(-c4cc5ccc(C6=NCCCN6)cc5[nH]4)cc3)[nH]c2cc1C1=NCCCN1 +O=C(Nc1ccncc1)Nc1ccc(-c2nc(N3CCOCC3)c3ccn(CCO)c3n2)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(C)c4ccc(S(C)(=O)=O)cc4)ncc23)ccn1 +CN(CCOc1ccc(F)cc1C(C)(C)C)C(=O)Nc1ccccc1C(=O)O +O=c1[nH]c(=O)n(CC(F)(F)c2ccccc2)nc1O +Cc1cnc(Cl)nc1-c1ccc(N(Cc2ccc(CNC(=O)C3CC3)cc2)C(=O)c2ccc(O)cc2O)cc1 +CC(C)Cc1sc(-c2cscn2)nc1C(=O)NCCCCC(=O)NO +Cn1c(=O)c2c(ccn2CC(=O)Nc2nc(-c3ccc(C(F)(F)F)c(F)c3)cs2)n(C)c1=O +COCCNc1nc(-c2ccc(OC)c(F)c2)cc2ncn(C)c(=O)c12 +O=C(O)COc1cccc2c1CCCC2CCC(=O)NN(c1ccccc1)c1ccccc1 +Cc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(OCc3ccccn3)nn1)CC2 +CCOC(=O)CNC(=O)Cc1ccc(Nc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 +CN(CCCN1CCOCC1)C(=O)c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1ccccc1OC)C(C)C +COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N2CCC(O)C2)cn1 +O=C(NCC1(CO)COC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CC1CN(c2nc(N3CCOCC3)c3sc(C(C)O)cc3n2)CC(C)O1 +Cc1cccc(-c2nc(C(F)(F)F)cn2-c2ccc(S(N)(=O)=O)cc2)n1 +Cc1cccc(-c2nc(CCOc3ccc4c(c3)CCC4CC(=O)O)c(C)o2)c1 +CC(C)c1ccc(N2C(=O)C(=CN(C)C)SC2=S)cc1 +CN(C)CCCOc1cc(F)c(-c2c(Cl)nc(-c3ncccn3)nc2NCC(F)(F)F)c(F)c1 +C#CCn1c(=O)[nH]c2[nH]c(-c3ccccc3)nc2c1=O +OCc1cccc2c1Cc1c(-c3ccc(-c4ccc(O)cc4)cc3)n[nH]c1-2 +CC1(NC(N)=O)CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(=O)NC(C)(C)C5CCC43C)C2C1 +CCOC(CN1CCN(CCc2ccc(C#N)c(OC)c2)CC1)c1ccc2c(c1C)COC2=O +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(F)cc2)CC1 +CC(NS(=O)(=O)c1ccc2c(Cl)cnc(N=C(N)N)c2c1)C(=O)O +CC(C)=C1c2ccccc2C=C(C2=CCN(C)CC2)c2ccccc21 +Cc1cc(C)cc(Sc2c(Cn3cnc(C)c3C#N)c(C)[nH]c(=O)c2I)c1 +CC(Nc1ccc(F)c(Cl)c1)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +Cc1ccccc1Nc1ncccc1C(=O)NCC(O)CN1CCN(c2ccccc2OC(C)C)CC1 +C=C(C)c1cccc(C(C)(C)NC(=O)Nc2ccc(Cl)c(C(=O)NC)c2)c1 +CC(C)C(=O)NCCCc1cccc2nc(-c3ccccc3)oc12 +NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cccc(C(F)(F)F)c1 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+CNC(C)C(=O)NC1CCC(NC(=O)Cc2ccccc2)CC2CCC(C(=O)NC3CCCc4ccccc43)N2C1=O +Cc1cc(Cc2ccc(Oc3ccccc3)cc2)n(O)c(=O)c1 +C=CCN(C)C(=O)NC1CCC(CNC(=O)c2ccccc2OC)(c2ccccc2)CC1 +CC(C)OC(=O)c1cnc(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)s3)CC2)c(Cl)c1 +COc1ccc(C(C)C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 +O=C(NCCCCN1CCCC1)C1C(C(=O)NCc2nc(Br)cs2)C2C=CC1C21CC1 +O=C(c1ccc2[nH]c(=O)c3c(c2c1)CCSC3)N1CCN(C2CCCCC2)CC1 +COCCOc1ccc2nc(C3(NC(=O)CC(N)Cc4cc(F)c(F)cc4F)CCS(=O)(=O)CC3)sc2c1 +Cc1c(CC(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 +CC(C)CS(=O)(=O)NCc1nc2cnc3[nH]ccc3c2n1C1CCN(CCC#N)CC1 +COc1cccc(CNc2ncnc3c(C(N)=O)cccc23)c1 +CC(C)(C)CC(=O)NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1 +N#Cc1c(N)nc(-c2ccccc2O)c(F)c1C1CCCNC1 +CC(=O)N1CC2C(C1)C2c1cc(-c2cnc(N)c(C(F)(F)F)c2)nc(N2CC3CC2C3)n1 +Cc1ncc(C(=O)O)c(NCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)n1 +CC(CC(C(N)=O)C(CCC(F)(F)F)C(=O)NC1N=C(c2ccccc2)c2cccc(F)c2NC1=O)C(F)(F)F +Cc1ccc(C=CCN(C)Cc2ccc3c(c2)OCCC3)cc1 +CN1CCN(c2ccc(C(=O)Nc3cc(-c4cccc(NS(=O)(=O)c5ccccc5)c4)n[nH]3)cc2)CC1 +CCc1sc2ccccc2c1C(=O)c1cccc2ccccc12 +Cn1cc(-c2cnc(Nc3cccc(Cn4nc(-c5ccc(Cl)c(C(F)(F)F)c5)ccc4=O)c3)nc2)cn1 +Cc1cc(NC(CCCCNCc2ccc(Cl)cc2)C(=O)NO)ccc1F +O=C(NC1CCC(CCN2CCN(c3nsc4ccccc34)CC2)CC1)c1cccnc1 +COc1cc(CN2CCCC23COC3)ccc1OC1CN(C(=O)c2nnc(-c3ccc(C(F)F)cc3)o2)C1 +Oc1ccc2c(c1)C1CCCN(Cc3ccccc3)C1CC2 +CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1 +FC(F)c1nnc(N2CCN(c3ncnc4sc(CC(F)(F)F)cc34)CC2)s1 +COc1ccc(-n2nc(C(F)(F)F)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)cc1 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(-c4ccccc4CN4CCC(O)C4)cc2)CC3)cc1 +O=C(NCCC(c1ccccc1)c1ccccc1)C1SC(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C(O)C1O +CC(O)C(COCCc1ccccc1)n1cnc2c(N)ncnc21 +O=c1cc2n(-c3ccccc3)nc(-c3ccccc3)nc-2cc1N1CCCC1 +C=CCc1ccc2c(c1O)-c1cccc3c1C(C2)N(CCC)CC3 +CN1C(=O)NCc2c(NC(=O)NC3CC(C)(C)Oc4c3ccc(F)c4Cl)cccc21 +CCCCCCCCC(O)c1ccc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2c1 +Oc1nc2cc(Cl)ccc2n1C1CCN(CC2COc3ccccc3O2)CC1 +COc1cccc(C=CC(=O)N2CC(CCl)c3c2cc(N)c2ccccc32)c1 +CCCc1nc2cc3ccccc3cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 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+O=C(Nc1ccc(Cl)cc1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CCC(=O)c1ccc(OCCCCOc2ccc(C(=O)O)cc2OC)c(C)c1O +COC(=O)C1C(C=Nc2ccccc2)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +CCC(N)C(=O)NC1C(=O)N2C(CCC1CNC(C)=O)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +CCCCCn1cc(NC(=O)C2CCCCC2)c(=O)cc1-c1ccccc1 +CCNc1nc(C)c2cc(-c3ccc(O)c(OC)c3)c(=O)n(C3CCCC3)c2n1 +CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)cc2OCC(C)C)c1 +O=S(=O)(Cc1ccc2c(c1)CCNCC2)c1ccc(-c2ccc(Cl)cc2)cc1 +Cc1ccc(-c2ccc3c(c2)N(c2nc4c(s2)C(=O)NC(C)(C)C4)CCO3)nn1 +CCNc1nc2ccc(OC)cc2cc1Cc1c(=O)[nH]c(COC)c2cc(OC)c(OC)cc12 +N#Cc1ccc(Nc2nc(N)nc(Cc3ccc(Cl)cc3Cl)n2)cc1 +Cc1ccc2c(c1)C(C(=O)Nc1ccccc1C(C)C)c1ccccc1CO2 +Cc1cccc2scc(Cn3c(=O)n(CCC(=O)O)c4ccccc43)c12 +O=C(Nc1cccc(Cl)c1)OCc1ccc(Cc2c[nH]cn2)cc1 +CN(C)CCCNC(=O)c1csc2nc(-c3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)cn12 +CCCCCCCCCC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC1C=CCCNC(=O)C=CC(C(C)C)NC1=O +Cn1cc(-c2cc3c(-c4ccc(Br)c(N5CCCC(O)C5)n4)n[nH]c3cn2)cn1 +C=C(c1ccccc1)C12CCCC1CC(CCCCCCCC)=C2c1ccccc1 +CC1CC(Nc2nc(N3CCOCC3)[nH]c(=O)c2-c2nc3ccccc3s2)C(O)C1O +NC(=O)c1nn(-c2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)c2ccccc12 +Cc1noc2c1C(=O)CC(CN1CCC(C(=O)c3ccc(F)cc3)CC1)C2 +O=C(c1csc2ccccc12)N(CCc1ccc(Cl)cc1)C1CCC2(CCCO2)CC1 +O=CN(O)C1(CS(=O)(=O)N2CCN(c3ccc(F)cc3)CC2)CCC1 +CCc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(CCc3cnc[nH]3)[nH]c(=O)c12 +Cc1ccc(CNc2nc(C#N)nc3c2ncn3Cc2ccccc2)cc1 +COc1ccc2c(c1)c(NCCCCN)c1c3ccccc3nc-1n2C +CS(=O)(=O)Nc1cnccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 +COCCCOc1cncc(C2NC(=S)NC3=C2C(=O)c2ccccc23)c1 +NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)c(F)c2)cn1 +CCc1ncnc(-c2ccc(C(=O)N3CC(C)NC(C)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCN(C)Cc1cccc(C=C2Oc3cc(OC)c(OC)cc3C2=O)c1 +[N-]=[N+]=NCCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12 +CC(=O)Nc1ccc(Nc2nc3c(c(Nc4ccccc4S(=O)(=O)NC(C)C)n2)CCN3)cc1 +Cc1cccc(Cn2cc(C(=O)NC3C4(C)CCC(C4)C3(C)C)c(=O)c3ccc(F)cc32)c1 +COc1cc(OC)c(C=C2CNCC(=Cc3c(OC)cc(OC)cc3OC)C2=O)c(OC)c1 +CN(C)CCOc1nc2cccnc2nc1C#Cc1cccc(F)c1 +O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2ccccc2)CC1 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+Fc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c(F)c1 +CCCCS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1 +CC#CCOc1ccc(S(=O)(=O)C(C(=O)NO)C2CCSCC2)cc1 +Nc1ccccc1NC(=O)c1ccc(C2CCN(Cc3ccccc3)CC2)cc1 +CN(C)CCN1CCN(C(=O)C2CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC2)CC1 +CCN(CC)CCCN=C(c1cccnc1)N(CCCN(CC)CC)c1ccnc2cc(Cl)ccc12 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)NCCO)nc3)cc12 +CN1CCC(C(c2ccccc2)N2CCN(C(=O)CC(c3ccccc3)c3ccccc3)CC2)CC1 +Cn1cc(-c2ccc(Cl)cc2)c(Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)n1 +O=C(Cn1c(=O)n(-c2ccccn2)c2ccccc21)Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ccccc21 +COc1ccc2cc(C(=O)C3CC3)cc(CCNC(C)=O)c2c1 +CC1NC(=O)C(c2ccc(F)cc2)=C1c1cc(F)c2c(c1)NC(=O)CO2 +CCC(NC(=O)C1CCCCN1CCOc1ccccc1)c1ccc(C(=O)O)cc1 +Cc1c(C(=O)NCCC2CCN(C)C2)sc2ncnc(Nc3ccc(F)cc3OC(C)CF)c12 +COc1cc(-c2cc(F)cc(F)c2F)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +O=c1[nH]c(N2CCN(c3cnccn3)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +CC(C)C1NC(=O)C(Cc2ccc(Cl)cc2)NCCOc2ccccc2CCCNC(=O)C(CN(C)C)NC1=O +COc1ccccc1N1CCN(CCc2ccc3nc[nH]c3c2)CC1 +Fc1ccc(-c2nnc3ccc(N4CCCCCC4)nn23)cc1 +CCNc1n[nH]c2cc(NC(=O)NCc3cccc(F)c3)ncc12 +CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1NC1CCC(O)CC1 +Cc1cc(C)cc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 +COc1cncc(-c2ccc3[nH]nc(C(=O)NCC4CCN(CC(=O)O)CC4)c3c2)c1 +CCN(CC)C(=O)c1ccc(C(=C2CCNCC2)c2ccccc2)cc1 +CN(c1nc2ccccc2s1)C1CCN(CCCCOc2ccccc2)C1 +Oc1cc(NCCCNC2CCNc3c(Cl)cc(Br)cc32)nc2ccccc12 +O=C(NO)C1C(c2ccccc2)C1c1cccc(-c2ncc(F)cn2)c1 +CC1CCN(c2cc(N3CCN(C)CC3)cnc2NC(=O)c2ccc(C#N)o2)CC1 +O=C1Nc2ccccc2C12CC2c1ccc2c(C=Cc3ccc(CN4CCOCC4)cc3)n[nH]c2c1 +COc1ccc(COC(=O)C2=C(C)NC(=S)NC2c2ccccc2)cc1 +CCCN(CCC)C(=O)Cc1c(-c2ccc([N+](=O)[O-])cc2)nc2c(Cl)cc(Cl)cn12 +O=[N+]([O-])c1cn2c(n1)OCC(Oc1ccc(OC(F)(F)F)cc1)C2 +FC(F)(F)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 +O=C1COc2ccc(CN3CCN(c4ccc(Cl)cc4)CC3)cc2N1 +CC1CCCCC1Oc1nc(N)c2c(=O)ccn(C3CCCCC3O)c2n1 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3C(=O)OC(C)(C)C)c1C +COc1ccc2ccc(CCc3c(C(=O)O)[nH]c(=O)[nH]c3=O)cc2c1 +CCOC(=O)CNC(=O)CCc1coc2cc(Cl)c(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc43)cc12 +N#Cc1cc(Cn2cncn2)ccc1-c1ccc(O)c(Cl)c1 +Cc1cn(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2F)cn1 +COC(=O)Nc1nc2ccc(C(=O)c3ccccc3C(=O)Nc3cccc(F)c3)cc2[nH]1 +CC(=O)N1CCC(OCc2cncc(-c3cnc4c(c3)CCCN4C(C)=O)c2Cl)CC1 +CC(=O)SCC(C)C(=O)N(CC(=O)O)C1Cc2ccccc2C1 +CNC(=O)c1ccc(C(=O)Oc2ccc(S(=O)(=O)C3(C(=O)NO)CCC4(CCNCC4)C3)cc2)cc1 +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(OCCO)c2c(CO)n1)c1ccccc1 +CCCCC1=NN(C(=O)NC2CC3CCC2(C)C3(C)C)C(C)(C)C1c1ccccc1 +Cc1csc(-c2nc(CCCCC(=O)Nc3ccccc3)[nH]c2-c2ccc3c(c2)OCO3)n1 +Cc1nc2ccc(C(F)(F)F)nc2n2c(-c3cc(O)ccc3Cl)nnc12 +CCNC(=O)c1ccc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4ccccc4O)cc32)cc1C +O=c1[nH]c(SCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2sc3c(c12)CCCC3 +CCCCCCCCCCCCCCCCn1c(O)nc2c(=O)[nH]c(=O)[nH]c21 +Cn1cc(-c2ccc(N3CCC(n4ncc5cc(F)ccc54)CC3)nn2)cn1 +CCCCc1nnc(SCc2cccc(OC)c2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +COc1cc(Br)c2c(c1)OCCN2c1nc(Cl)cn(C(C)C2CC2)c1=O +N=C(N)NCCC(=O)NCC1(Nc2ccccc2)CCN(Cc2ccccc2)CC1 +N#Cc1ccccc1N1CC2C(C1)C2NCC(=O)N1CC(F)CC1C#N +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1c[n+]([O-])c(CNC(=O)OC(C)(C)C)cc1c2C +NS(=O)(=O)c1ccc2nc(-n3cc(C=NO)c(-c4ccc([N+](=O)[O-])cc4)n3)sc2c1 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)N1CCN(c2ccc(Cl)cc2)CC1 +CN1CCN(C(=O)NC2CCN(Cc3ccn(-c4ccc(C(F)(F)F)cc4)c3)CC2)C(c2ccccc2)C1 +CC(C)Nc1nc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc2[nH]1 +N#Cc1ccnc(Nc2nccc3nc(-c4c(Cl)cccc4Cl)[nH]c23)c1 +COc1cc(C(=O)C=C2c3ccccc3C(=O)c3ccccc32)cc(OC)c1OC +Cc1ccccc1-c1nc(C(=O)Nc2cccc(C(=O)O)c2)c(CCC2CCCCC2)[nH]1 +Cc1ccc2c(N3CCN(Cc4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1 +O=C(Cc1ccc(Cl)cc1)NC(Cc1ccc(Cl)cc1)C(=O)NC1CCC(O)CC1 +COc1c(NC(=O)c2ccc(NS(C)(=O)=O)cc2)cc(-c2ccc[nH]c2=O)cc1C(C)(C)C +Cc1cc(-c2cncs2)cc2c(NC3CCOCC3)cc(=O)n(C)c12 +Cc1nnc(-c2cccc(CN3CCN(C(=O)c4ccc(CC5CCC(C(O)c6ccccc6)N5)cc4)CC3)n2)o1 +CCC(C)C(CN1CCCC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +Cc1ccc(CN2CCC(O)C(N3CCC(c4ccccc4)CC3)C2)cc1 +O=C(C=Cc1ccc(Cl)c(Cl)c1)N1CCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1cccc(C(=O)N2CC(C)OCC2Cc2cc(-n3nccn3)ccc2F)c1-n1nccn1 +CCN(CCOC)c1nc(C)nc(N(CC)c2c(C)cc(C)cc2C)n1 +Cc1cncc(-c2nc(C(F)(F)F)cn2-c2ccc(S(N)(=O)=O)cc2)c1 +CC(C)C(CO)Nc1ccc2ncc(-c3cccnc3)n2n1 +CC(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccccc1)C(C)c1nc2ccccc2c(=O)n1-c1ccccc1 +CC1(C)CCCC(Oc2cc(F)c(C(=O)NS(C)(=O)=O)cc2Cl)C1 +Cn1cc(-c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cn1 +CC(NC(=O)Nc1cccc(-c2nnnn2C)c1)C(O)CN(C)C(C)C(O)c1ccccc1 +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1cc(F)cc(F)c1 +CCCCOc1ccc(-c2c(F)ccc(C(=O)O)c2F)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F +Cc1c(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CCO2)ccc2c1COC2=O +O=C(O)COc1ccc(OCc2cc(-c3ccc(C(F)(F)F)cc3)cc(-c3ccc(C(F)(F)F)cc3)c2)cc1 +O=C(O)c1cn(C2CC2)c2c(OC(F)F)c(N3CCN(c4ccc(F)cc4)CC3)c(F)cc2c1=O +CCCCCC(=O)OCC1(CCl)OC(n2ccc(N)nc2=O)C(F)C1OC(=O)CCCCC +CC(C)C(NS(=O)(=O)c1ccc(-c2ccccc2)cc1)C(=O)O +CCn1cnc(-c2cc3nccc(Oc4ccc(NC(=O)CC(=O)Nc5ccccc5OC)cc4F)c3s2)c1 +CNC(=O)C12CC1C(n1cnc3c(C=C(O)c4ccccc4Cl)nc(C#Cc4ccccc4Cl)nc31)C(O)C2O +Cc1cc(OCCNc2ccncc2)cc(OS(=O)(=O)c2ccccc2[N+](=O)[O-])c1 +CN1CCN(C2Cc3ccccc3Sc3ccc(-c4nnnn4C)cc32)CC1 +OCC(O)CN1CC=C(c2[nH]c3nccc4c3c2COc2ccc(F)cc2-4)CC1 +CNS(=O)(=O)Nc1cccc(Cc2c(C)c3ccc(OC(=O)N(C)C)cc3oc2=O)n1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NC(C)C(=O)NCc3ccco3)[nH]c3ccc(Cl)cc23)c1 +C#CCN(Cc1cc2c(O)nc(C)nc2cc1C)c1ccc(C(=O)NC(CSc2nn[nH]n2)C(=O)O)c(F)c1 +COC1C(CO)OC(n2c3ccc(Br)cc3c3c4c(c5c6cc(Br)ccc6[nH]c5c32)C(=O)NC4=O)C(O)C1O +COc1ccc(-c2ssc(=NO)c2-c2cc(OC)c(OC)c(OC)c2)cc1N +c1ccc(-c2ccc(-c3c[nH]c(C4Cc5c([nH]c6ccccc56)C(C5CCOCC5)N4)n3)cc2)cc1 +O=C1NCN(c2ccccc2)C12CCN(C1CCCc3ccc(Cl)cc31)CC2 +Nc1ncc2c(-c3cnn(C4CCNCC4)c3)coc2c1OCc1c(Cl)ccc(F)c1Cl +CS(=O)(=O)c1cccc(C=CC(=O)NC2CCC(CCN3CCc4cc(C#N)ccc4C3)CC2)c1 +CN1CCN(Cc2ccc(C(=O)NN(CC3CCCO3)c3nc(C#N)ncc3Br)cc2)CC1 +O=C(CCCCCCCSc1nc(O)cc(Cc2ccccc2)n1)NO +NS(=O)(=O)c1ccc(NC(=O)C=Cc2ccc(OC(F)(F)F)cc2)cc1 +COP(=O)(Nc1ccc(-c2cc3ccc(OS(N)(=O)=O)cc3oc2=O)cc1)OC +Oc1ccc2c(c1)C(c1ccc(OCCN3CCCCC3)cc1)c1c-2ccc2cc(O)ccc12 +CCCCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CC(C)CCNC(=O)c1ccc(C#Cc2ccccc2)nc1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccc(OCC(=O)O)cc1 +CC1C2Cc3cc4nc(O)[nH]c4cc3C1(C)CCN2CC1CC1 +CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CC(C)(N)C3)c2c1Cl +Cc1cc(C)cc(C(CC(C)C)NC(=O)c2cc(COc3cccc(F)c3)ccc2CCC(=O)O)c1 +N#Cc1c(C=Cc2ccccc2)[nH]c2nc(N)[nH]c(=O)c12 +CN(C(=O)c1cc2c(s1)-c1ccccc1OC2)c1ccccc1Cl +CCC(C)C(N=C(S)Nc1ccccc1)C(=O)NC(C=O)Cc1c[nH]c2ccccc12 +O=C1C(=O)N(CNc2ccc(Br)cc2)c2ccccc21 +COC(=O)N(CC(=O)O)Cc1cc(OCc2nc(-c3ccc(F)cc3)oc2C)ccc1F +Brc1cccc2c1[nH]c1c[n+](Cc3ccc4ccccc4c3)ccc12 +Nc1nc(-c2ccccn2)c(-c2ccnc3ccccc23)s1 +CCCS(=O)(=O)Nc1cccc(-c2nn(C(C)C)cc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +CC12CCC(=O)C=C1CCC1C2CCC2(C)C(C3N=CC=N3)CCC12 +CN(CCCCNC(=O)c1cc2ccccc2[nH]1)C1Cc2cccc3[nH]c(=O)n(c23)C1 +Nc1ncnc2c1sc1cc(-c3cccc(C(=O)O)c3)ccc12 +CNc1nc(N)nc2nc(-c3ccccc3C(F)(F)F)ccc12 +O=C1OC2(CCN(c3nc4c(Cl)cccc4[nH]3)CC2)c2ccccc21 +N=C(N)c1ccc2oc(-c3cccc(OCCCOc4ccccc4)c3)cc2c1 +O=C(NCc1cc[nH]c1)C(=O)c1c[nH]c2ccc([N+](=O)[O-])cc12 +CCOC(=O)c1ncn2c1Cn1cnnc1-c1cc(O)ccc1-2 +Cc1cnccc1-c1nc(C)c2c(C)nc3c(F)cc(OCC(F)(F)F)cc3n12 +COc1ccc(CNC(=O)c2cc(-c3cncc(C)c3)nnc2-c2ccccc2)nc1OC +CCON1CCC(Nc2ncc(C(=O)NO)cn2)(c2ccccc2)CC1 +c1ccc(OCCCN2CCN(c3cccc4ccoc34)CC2)cc1 +O=C(c1ccc2c(c1)ncn2-c1cccc(C(F)(F)F)c1)N1CCCCC1 +C1=C(Cc2ccccc2)CCN(CCC(c2csc3ccccc23)N2CCOCC2)C1 +CCCC(C)n1ccnc1C=CC=CC(=O)C=Cc1nc2ccccc2n1C(C)CCC +O=C(O)Cc1ccc(-c2ccc(NC(=O)c3cccc(-c4ccc(O)c(O)c4O)c3)cc2)s1 +COc1ccccc1CN(C(C)=O)c1cnccc1Oc1ccccc1 +CC(=O)N1CCc2c(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n[nH]c2C1 +CNC(=C[N+](=O)[O-])Nc1cccc(-c2csc(N=C(N)N)n2)c1 +O=C(O)c1cc(-c2ccc(C(O)C(F)F)cc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1 +COc1cc2c(cc1OCCN1CCCCC1)C(=O)C(=Cc1ccncc1)C2 +COCCOc1ccc(CN(C)C(=O)c2ccc(S(=O)(=O)Nc3ccccc3)cc2)cc1 +NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3Cl)ccc2Cl)n(-c2ccccc2)n1 +O=C(CCN1CC=C(c2ccc(Cl)cc2)CC1)c1ccccc1 +CCCN(CCC)Cc1cn(-c2cc(NC(=S)NCC)ncn2)cn1 +FC(F)(F)c1cccc(CCNC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)c1 +CC(C)(C)c1ccc(Cn2nc(-c3ccc(Cl)cc3)cc2C(=O)NN=Cc2cccc(O)c2O)cc1 +Cn1c(N2CCC(F)(F)CC2)cc(OCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O +CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4nc5ccccc5[nH]4)cc3)nc2n(CCCOC)c1=O +C=CC=CC(C)C(O)C(C)C(O)C(C)CC(C)=CC(C)C(O)C(C)C=CC(O)CC1OC(=O)C(C)C(O)C1C +COc1cc(-c2ccc[nH]2)c2c3c(ccc(F)c13)NC2=O +N#Cc1ccc(C(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c2cccnc2)cc1 +Cc1nn(-c2cncc(C(C)(C)O)c2)c2ccccc12 +O=[N+]([O-])c1cc2cn[nH]c2c2c1[nH]c1ccc(Cl)cc12 +Cc1ccc(-c2ccccc2C(=O)N2CC3CN(c4cnc5ccccc5n4)CC3C2)cc1 +O=C1CCCN1CCCCN1CCN(c2ccc(F)cc2F)CC1 +CCc1nc(C(F)(F)F)cnc1NC1CCCC1NC(=O)c1cc(F)ccc1-c1ncccn1 +N#Cc1cc(-c2ccnc(Nc3ccc(C(=O)NCCO)cc3)n2)cnc1N1CCC(F)C1 +CN(C)CCNc1ncc(C(N)=O)c(Nc2cccc(C(F)(F)F)c2)n1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(ncnc2-c2ccc[nH]2)C1 +COc1ccc2occ(C(=O)Nc3cccc(Cl)c3)c(=O)c2c1 +O=P(Oc1ccccc1)(Oc1ccccc1)OC1C=CS(=O)(=O)C1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCCF +CN(CC(=O)NC(CCCCN)C(=O)C(=O)NCCN1CCOCC1)C(=O)c1ccccc1Sc1ccccc1C#N 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+c1cc(-c2cncc(NCC3CCOCC3)n2)c2cc(C3CCNCC3)[nH]c2n1 +COCC1CCCN1c1cccc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)n1 +CN(C(=O)c1ccccc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +COC(=O)c1ccc(Nc2nnc(SCc3ccccc3C)[nH]2)cc1 +O=c1cc(NC2CCN(Cc3ccc4ccccc4c3)CC2)c2cc(Cl)ccc2o1 +O=C(O)Cc1ccc(-c2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)cc1 +CSCC(NCc1c[nH]c2c(=O)[nH]cnc12)C(O)CO +CC(=NNC(=O)c1cc(Br)ccc1O)c1cc2cc(Br)ccc2n1C +CCC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCC2COc3ccccc3O2)c1=O +N#Cc1ncc(C2=CCC(N(CCN3CCCC3)C(=O)Nc3ccc(F)c(Cl)c3)CC2)s1 +Cc1cc(C)cc(-c2[nH]c3ccc(C(C)(C)C(=O)N4CCCCC4)cc3c2CCNCCCCc2ccncc2)c1 +CN(C)c1ccccc1N1CCN(Cc2ccc(F)cc2Cl)C(=O)C1=O +CC(C)c1nc(CN2CCC(OC3CCC(Oc4cnc(S(C)(=O)=O)cn4)CC3)CC2)no1 +CC(c1ccccn1)n1[nH]c(=O)c2nc3cc(Cl)ccc3c(O)c2c1=O +CCC(Nc1cc(CN2CC(C(=O)O)C2)ccn1)c1ccc(Cl)c(C)c1 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1ccc(C#N)cc1 +O=Cc1cc(O)cc2ccc(-c3ccc(O)c(F)c3)cc12 +Cc1cccnc1C(=O)Nc1cnn2ccc(N3CCCC3c3cccc(F)c3)nc12 +CC(C)c1n[nH]c2cc(OCCNCC(O)c3cccc(NS(C)(=O)=O)c3)ccc12 +CCn1cnc2c(-c3ccc(F)c(-c4ccc(S(C)(=O)=O)cc4F)c3)cnnc21 +CC1CN(c2ccccc2Cl)C(=O)c2cc(COc3ccc(F)cn3)nn21 +COc1ccc(CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)c(OC)c1 +O=C1N(c2ccc(C3CCC(N4CCCC4)CC3)cc2F)CCC12CCNCC2 +CC(NC(CCc1ccccc1)C(=O)O)C(=O)N1CC(NC(=O)C(CS)Cc2ccccc2)CC1C(=O)O +Cc1cc(Oc2ncccc2N2CC(F)(F)C2)ccc1-c1c(C)c(=O)[nH]c(=O)n1C +O=C(OCc1ccc(Cl)c(Cl)c1)C1(c2ccc(I)cc2)CCNCC1 +COc1cc(Nc2ncc3ccn(-c4cccc(C(=O)NCCNC(C)=O)c4)c3n2)cc(OC)c1OC +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccc(C(F)(F)F)cc4)ncc23)ccn1 +CC(=O)c1cn(CC(=O)N2C(C(=O)Nc3cccc(Br)n3)CC3CC32)c2nnccc12 +CC(C)C(O)(c1ccc2cc3c(cc2c1)CN(C)C3=O)c1c[nH]cn1 +CC(C)=CCCC(C)CC(=O)OCC1=C2C(=CC3(C)CCC(O)(O3)C(C)CC2O)OC1=O +N#Cc1cnn2c3cc(nc12)N1CC(CC1CO)OCC=CCOc1cccc(c1)N3 +COc1ccc(-c2cc(-c3c(OC)cc(OC)c(C4CCN(C)C4CO)c3O)n[nH]2)c(OC)c1 +CC(=O)Oc1ccc(C(=O)C=Cc2ccc3c(ccn3C)c2)c2c1C=CC(C)(C)O2 +Cn1cncc1CN1CC(N(CC2CCN(C(=O)C(C)(C)C)CC2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21 +NC(=NCCC(c1cccc(N)c1)c1ccccn1)NCCCc1c[nH]cn1 +Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)CC3)C2=O)cc1C 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+COc1cc(C(=O)N2CCN(C)CC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)c2nc[nH]c2c1C(N)=O +N#Cc1ccc(N2C(=O)C3C(O)CCN3C2=O)c2ncccc12 +CC(C)Sc1nc2c(c(Nc3ccc4c(c3)N(C)CCC4(C)C)n1)CCN(c1ncccc1C(F)(F)F)CC2 +CCSc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2noc(S)n2)cc1 +O=C(NC1CCC(O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1Cl +O=C(O)C(O)=CC(=O)c1cc(Cc2ccccc2F)cn(Cc2cccc(F)c2F)c1=O +CCC(N)C(=O)NC1C(=O)N2C(CCC1CCN)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +O=C(c1ccccc1)N1CCC2(CC1)CCN(C(=O)N1CCN(C3CCC3)CC1)C2 +CC(C)(N)C=C(C#N)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cccc(F)c3)cc2F)c2c(N)ncnc21 +Cc1ccc(Cn2c(C3CNCCO3)nc3ccccc32)cc1C +Cc1ccc(OCC(=O)Nc2ccc3c(c2)OCO3)c(C)c1 +Cc1nc(-c2ccc(Cl)cn2)nc(NCC(NCCCCCc2ccccc2)c2ccccc2)c1Cl +O=C(O)c1cccc(NC(=O)C2NC3(CCCCC3)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)c1 +O=c1ccc2cnc(Nc3ccc(N4CCOCC4)cc3)nc2n1C1CCCC1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4ccc(NC5CCOCC5)nn4)ccn23)c1 +CN1CCc2ccc(Nc3nnc(-c4cccc(-c5cccnc5)c4)o3)cc2C1 +COc1ccc2c(c1)COc1cc(Nc3ccccc3N)ccc1C2=O +NC(=O)C(NC(=O)c1ccc(C2CC2)c(OCC(F)(F)F)n1)c1ccccc1 +CC(C)(C)c1nc(N2CCN(CCCCNC(=O)c3cn4ccncc4n3)CC2)cc(C(F)(F)F)n1 +CC(C)c1c(Cc2c(F)cccc2F)nc(SCC(=O)c2ccccc2)[nH]c1=O +NC1(CNC(=O)c2ccc(F)cc2)CCN(c2ncnc3[nH]cc(Cl)c23)C1 +Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(NCCN2CCCC2)nc1 +CCN(CC)C(=O)Cn1c(=O)c(C(=O)NC)c(O)c2ncc(Cc3ccc(F)cc3)cc21 +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C(C#N)=Cc3cnc[nH]3)c2)n1 +CN1CCN(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)CC1 +COC1Cc2c(csc2-c2cccnc2)C2(CCN(Cc3ccccc3)CC2)O1 +N#Cc1ccc(OCc2ccc3c(c2)OCO3)cc1OC(C(=O)O)c1ccccc1C(F)(F)F +O=S(=O)(c1ccc(Cl)cc1)c1snnc1-c1ccccc1 +CCCCCCCCCCCCn1nnc(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccc(OC)cc2)n1 +CC(C)c1nc2ccccc2n1Cc1ccc(C(=O)NC2CC3(CCCO3)CC2C(=O)NO)cc1 +COc1cc(CC(C)C(=O)N2CCN(c3ccc(C(F)(F)F)cc3C(N)CC(C)C)CC2)ccc1Cl +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cc(CO)c(F)c4[nH]nc(N)c34)cc2)c1 +Nc1ccc(C(=O)N2CCC(N3CCCCC3)CC2)cc1Cl +CC(NC(=O)Nc1cc2[nH]nc(-c3ccc(C#N)cc3)c2cn1)c1ccc(F)cc1 +CCc1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)oc(-c2ccccc2)c1-c1ccccc1 +CCCCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 +Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C4CC4)cc3)ccc2N2CCN(C)CC2)c1Cl +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)OC2CC3OCCOC3C2)cc1 +CCCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=[N+]([O-])c1c(Nc2ccccn2)cc(Cl)c2nonc12 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C)CC3C)c(F)c2)c1C#Cc1ccc(N)nc1 +Cn1cc(C2=C(c3coc4cc(F)c(F)cc34)C(=O)NC2=O)c2ccc3ccccc3c21 +COc1cc(Br)c(S(=O)(=O)Nc2ccc(C(F)(F)F)c(OCC3CCCN3C)c2)cc1OC +O=C(C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(Cl)cc1)N1CCCCC1 +CC1(C)Oc2ncnc(N)c2N=C1c1ccc(C23CCC(C(=O)O)(CC2)CC3)cc1 +O=c1[nH]c2c(O)ccc(C(O)CNCCCSCCOCCc3cccc4ccccc34)c2s1 +CC(CO)NC(=O)c1cccc(-c2cc(Nc3cccc(N4CCCC4C)n3)c3nccn3n2)c1 +CN1CCC(N2CC(c3ccccc3)(c3ccccc3)NC2=O)CC1 +O=C(Nc1ccc(C=Cc2ccc(NC(=O)C3CCCN3C(O)C3CCCCC3)cc2)cc1)C1CCCN1C(O)C1CCCCC1 +CCN(CC)C(=O)c1ccc(N(c2cccc(OC)c2)C2CCN(CC3CC3)CC2C)cc1 +OC(CNCc1ccccc1OCc1ccccc1)c1cccc(Cl)c1 +Cc1cc(CN2CCN(c3c(Br)cnc4[nH]c(-c5ccc(OCCO)cc5)nc34)CC2)no1 +Cc1cc2cc3c(cc2[nH]1)NC(=O)C(C)CCCC(N1CCC(c2c(F)ccc(Cl)c2F)=CC1=O)c1cc-3ccn1 +CCCC(=O)NC1CCN(c2cccc3oc(CCCCc4ccccc4)cc23)C1 +Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NC(C)C)cn1 +Nc1nc(-c2ccco2)c2cnn(CCCc3ccccc3)c2n1 +CCS(=O)(=O)c1ccc2[nH]c(-c3cccc(-c4ccccc4)c3F)nc2c1 +N#Cc1ccc2cc1Oc1ccc3cccc(c3c1)C(=O)NCCNC(=O)Cc1cncn1C2 +OC1CCC(OCc2ccc(F)cc2)CC1N1CCN(c2ccccc2)CC1 +Clc1ccc2c(NCCn3cnc4c(N5CCN(c6ccccc6)CC5)nc(Cl)nc43)ccnc2c1 +CC(=O)NC(CCCCN)C(=O)Nc1ccc(C(=O)NC(CC(=O)O)C(=O)O)cc1 +O=C(c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3CCc2ccccc2)cc1)N1CCCC1 +O=C(C=Cc1ccc(I)cc1)Nc1ccc2c(c1)OCCO2 +Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1Nc1nccc(-c2cncnc2)n1 +CCCCC1c2c(nc3c(c2N)CCCC3)Oc2c1c(=O)oc1ccccc21 +Cc1nc(NC(=O)N2CCCC2C(N)=O)sc1-c1ccnc(C2CCC2)n1 +CCCCCCCN=C(N)Cc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +O=C1OC2(CCC(C(=O)Nc3ccn(-c4ccccc4)n3)CC2)c2cnccc21 +CCC(CO)Nc1nc(NCc2ccccc2)c2c(n1)N(C(C)C)CN2 +COc1cc2c(ccn2-c2cccc3c2ccn3C)c(OC)c1OC +CCOC(=O)Cc1ccc(NC(=O)c2cc(C#N)c[nH]2)c(C2=CCC(C)(C)CC2)n1 +CCC(NC(=O)c1c(OCCO)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +Cc1ccc(N2CCN(CCCCOc3ccc4c(=O)cc(-c5ccc(Cl)cc5)oc4c3)CC2)cc1 +CC(O)C(CCCc1ccccc1)n1cnc2c(N)ncnc21 +O=C(CC1CC1)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +CC1(c2cc(NC(=O)c3cnc(C(F)F)cn3)cc(Cl)c2F)CC(C(F)(F)F)OC(N)=N1 +C=CC(=O)N1CC(N2C=C(C#Cc3cc(OC)cc(OC)c3)C3C(N)=NC=NC32)C1 +Cc1ccc(NC(=O)c2cnoc2C)cc1C(=O)Nc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1 +CCOc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)ccc1C +O=C(CCCN1C(=O)c2ccccc2C1=O)N1CCCCCC1 +C#CCN(Cc1cc2c(=O)n(C)c(CO)nc2cc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +CN(C)C(=O)Cn1cc(-c2nc(C3(c4ccc(-c5cnc(N)cn5)nc4)CCC3)no2)cn1 +CCCCCCc1nc2cc(C=CC(=O)NO)ccn2c1NCCC(=O)NCC(C)(C)CN(C)C +Cc1nc(NC(C)C(Cc2ccc(Cl)cc2)c2cccc(Br)c2)cc(N(C)C)n1 +Cc1ccncc1Oc1ncnc(OC2CCN(C(=O)OC(C)C)CC2)c1C +CN(Cc1ccccc1)C(=O)c1nc(-c2ccccc2F)c2ccccc2n1 +FC(F)(F)c1nc2c(c(NCc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)n1)CCCC2 +CCCOc1cnc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c(Cl)c1 +Cc1cc(-c2n[nH]c3c2CN(C(=O)NC2CCCN(Cc4c(C)cccc4C)C2)CC3)ccn1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c(Cl)c1 +CCCc1cccc(-c2cc(NC(=O)C3CC(=O)NC3C)nn2-c2ccccc2)c1 +O=C(Nc1ccc(Nc2ncnc3cc(OCCCN4CCN(CCO)CC4)ccc23)cc1)NC1CCCCC1 +CCCCCN=c1ccn(-c2ccc3ccccc3c2)c2cc(Cl)ccc12 +CCCCC12CC1(COC(C)=O)C(=O)Nc1ccc(Cl)cc12 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCOc1ccc(C(=O)N3CCCC3)cc1)C2 +COc1cccc(NC(=O)c2ccc(NCCCN3CC(C)CC(C)C3)c([N+](=O)[O-])c2)c1 +O=C1CCc2ccc(OCCCCN3CCC(O)(c4ccc(Cl)cc4)CC3)cc2N1 +COc1ccc(CC2CCCC2)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)Nc2cnn(C)c2)cn1 +C=CCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)c2cc1OC +O=C(N(CCN1CCN(c2ccccc2O)CC1)c1ccccn1)C12CCC(CF)(CC1)C2 +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCNCC2CC2)CC1 +CCCCCCc1c(-c2ccccc2)nc2ccccc2c1C(=O)NC(CC)c1ccccc1 +COCc1c(-c2cc3cccc(OC)c3s2)c2c(N)ncnn2c1CN1CCNC(=O)C1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC(CO)C2)c(-c2cccnc2)c1 +CC(C)(CCN)CN(CC1Cc2ccccc2CN1)C1CCCc2cccnc21 +O=c1cc(OCc2ccccc2Cl)ccn1-c1ccc(OCCN2CCCC2)cc1 +O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O +COc1ccccc1N1CCN(CCC(O)c2ccc([N+](=O)[O-])cc2)CC1 +CCCC(=O)Oc1ccc2nc(S(N)(=O)=O)sc2c1 +O=[N+]([O-])c1c(Br)c(Cl)cc2nc(O)c(O)nc12 +COCCCN1CC(C)N(C(=O)N2Cc3c(NC(=O)c4ocnc4C)n[nH]c3C2(C)C)CC1C +CN1CCN(c2cc(-c3ccc(I)cc3)nc(N)n2)CC1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CCN5CCCC5C4=O)cn3)nc2n1C1CCCCC1 +COc1cccc(C)c1Oc1ccc(S(=O)(=O)Nc2ccc(F)cn2)cc1C#N +O=C(CN1CCN(c2cccc3c2cnn3-c2ccccc2F)C1=O)N1CCCC1 +Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2nc(N3CCNCC3)cnc2c1 +CCCCCCCCCCCC(=O)NC(CCC(=O)NC1CCCCNC1=O)C(=O)O +Cc1ccc(F)cc1C(=O)Nc1ccc(N2CCC(N3CCCC3C)C2)cc1C(F)(F)F +Cc1cccc(CC(NC(=O)C(c2ccccc2)c2ccccc2)C(=O)NC(C#N)COCc2ccc(C(=O)O)cc2)c1 +CC(c1ccccc1)N(C)C(=O)Nc1nc(-c2ccncc2)cs1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCN(c2ccccc2Cl)CC1 +CC(=O)NCCCNC(=O)C12CC1C(n1cnc3c(NC(C4CC4)C4CC4)nc(Cl)nc31)C(O)C2O +O=c1nc(Nc2ccc(OC3CCCC3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c(=O)n1CCO +CNCc1cc(-c2ccc3c(C(=O)NCCN(C)C)cc4n[nH]c(=O)n4c3c2)cs1 +O=C1C2=C(C3=NCCc4c(Br)[nH]c1c43)C1(C=C(Br)C(O)C(Br)=C1)CCN2 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OC2CCOCC2)c(-c2cncnc2)c1 +O=C1Nc2ccc(S(=O)(=O)N3CCCC3COCCF)cc2C1=O +CC(C)(C)c1ccc(C(=O)Nc2ccccc2S(N)(=O)=O)cc1 +CC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)cc3)c2)c2cncnc21 +CN(Cc1nc2ccccc2n1C)C(=O)c1ccc2c(c1)CN(C)C(=O)C(CC(=O)O)N2 +CCOc1ccccc1CC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3OCC)s2)s1 +CNC(=O)c1c(C(N)=O)nn2c1C(C)COc1ccc(C#CC(C)(O)c3cc(C)on3)cc1-2 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCCN +CN1CC2(C(=O)NC(=O)NC2=O)N(c2ccc(Oc3ccc(F)cc3)nc2)C1=O +Cc1ccn2c(C(=O)Nc3cc(-c4noc(C5CC(F)C5)n4)ccc3C)cnc2c1 +COc1cc(OC)cc(C(=O)N(CCCc2ccccc2)Cc2ccc(Oc3cccc(C(=O)O)c3)cc2)c1 +O=C(O)COC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 +Cn1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccc(F)cc3)cc21 +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(N3CCOCC3)nc12 +CCc1ccc2c(-c3ccc(S(C)(=O)=O)cc3)c(-c3ccc(F)cc3)nn2n1 +O=C(Cc1ccc(CCCCc2ccc3[nH]ccc3c2)cc1)NO +COc1ncc(-c2cc(F)cc(-n3nnc(-c4ccccn4)n3)c2)cn1 +COc1ccc(C(F)(F)F)cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1 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+COCCN(CCOC)c1nc(C)nc2c1nnn2-c1c(C)cc(C)cc1C +Cc1cccc2nc(-c3cccnc3N3CCN(C4CCN(C)CC4)CC3)oc(=O)c12 +COC(=O)c1ccc2c(c1O)C(=O)c1ccccc1C2=O +CC(=O)Nn1c(Cc2csc(NCCC(=O)O)n2)nnc1SCC(=O)NN +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccnc(Cl)c4c3)CC1)C2 +Nc1ccc(-n2nc3c(=O)[nH]c4ccccc4n3c2=O)cc1 +C#Cc1cccc(N2C(=O)c3ccccc3C2(O)c2ccc3[nH]c(NC(=O)OC)nc3c2)c1 +O=C(NNc1cccc2nc(Cl)ccc12)C12CC3CC(CC(C3)C1)C2 +Cc1c(OCC2CN(C)c3ccccc3O2)ccc(C(=O)Nc2cc(CC(=O)O)ccc2Cl)c1C +Fc1ccc(-c2nc(-c3ccccn3)c(C3CCN(CCc4ccccc4)CC3)s2)cc1 +COc1ccccc1-c1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)C(=O)O)cc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NN)cc3)[nH]c2n(CCC)c1=O +CCC=CCC=CCC1(O)C=C(Cl)C(=O)C1=CC(OC(C)=O)C(CCCC(=O)OC)OC(C)=O +CCN1CCC(c2ccccc2)=C(C(=O)OCCc2ccc(OC)cc2)C1 +CN1CC(NC(=O)c2ccc3cc(Oc4ccc(C(F)F)cn4)ccc3n2)CC1=O +NC(=O)C(=O)NNC(=O)Nc1cccc2c1C(=O)c1c-2n[nH]c1-c1ccc(O)cc1 +c1ccc(-c2nn(-c3ccccc3)[n+](-c3cccc4ccccc34)n2)cc1 +COc1ccc(N2CC=C(c3ccc(OC)c(OCCN4CCCCC4)c3)C2=O)cc1Cl +O=C(Nc1ccc(-c2ccccc2)cn1)c1cccc(Cl)c1 +CC(O)CNC(=O)C(Cc1ccccc1)N(C)C(=O)C(Cc1ccc2ccccc2c1)N(C)C(=O)C=CCC(C)(C)N +CN(Cc1ccccc1)Cc1nnnn1C1CCN(Cc2ccc(-n3ccnc3)cc2)CC1 +COc1ccc2c(c1F)C(=O)N(CC1(C#Cc3cccnc3)NC(=O)NC1=O)C2 +COc1cc2[nH]c(C)c(-c3ccc(O)cc3)c(=O)c2cc1Cl +CCOC(=O)N=C(N)Nc1ccc(-c2ccc(-c3ccc(NC(N)=NC(=O)OCC)cc3)cc2)cc1 +COCC1CN(C(=O)c2c(Oc3c(C)cccc3C)n(C3CCCCC3)c3cccnc23)CCN1 +Cc1ccc(C(=O)N(N=C2C(Cl)=C(Cl)C(Cl)=C2Cl)C(=O)c2ccc(C)cc2)cc1 +CN(CCCCNc1c2c(nc3ccccc13)CCCC2)CCCNc1c2c(nc3ccccc13)CCCC2 +c1cc(Nc2[nH]nc3ccnc(OC4CCOCC4)c23)ccn1 +O=[N+]([O-])c1c2c(cc3nc(O)c(O)nc13)CCC2 +CC(C)(C)Oc1ccc(CC2C(=O)Nc3ccccc3N2Cc2ccc(C(=O)NO)cc2)cc1 +Cc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2F)c1 +CC(C)C1CN(CCN2CCN(C)CC2)C(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1 +CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(-c4cccc(OC)n4)cc32)c1C +Cc1ccc(Nc2nc(NN=Cc3ccc4c(c3)OCO4)nc(N3CCOCC3)n2)cc1 +CC(C)(O)c1nc(-c2cccc(CNC(=O)c3cnc(-c4ccccn4)nc3)c2)no1 +CC1=C(CCCCCC(=O)O)C(=O)c2ccccc2C1=O +COC(=O)c1c(NC(=O)CSc2ccc([N+](=O)[O-])cc2)cnn1CCc1ccccc1 +COc1cc(CNCCN2CCC(Cc3ccccc3)CC2)ccc1O +COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+](=O)[O-] +Nc1ncnc2c1c(-c1ccc3nc(Cc4ccccc4Cl)[nH]c3c1)nn2C1CCC(N2CCOCC2)CC1 +O=C(NCc1ccccc1O)c1cc(C(=O)c2ccccc2F)c[nH]1 +COC(=O)C1C(c2ccc3ccccc3c2)CC2C(O)CC1N2C +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)c(C(C)=O)cc21 +CCCCc1nc(C)n(Cc2occc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cn1ncnc1COc1nn2c(-c3cc(CO)on3)nncc2c1C(C)(C)C +Nc1ncn(CC(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)n1 +CC1CN(C(=O)c2ccc(N(C)C)cc2)CCN1c1nc(-c2ccncn2)cc(=O)n1C +COc1cccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOCC4)N3)n2)n1 +CC(NC(=O)c1cc(Cl)cnc1Oc1ccc(F)cc1)c1ccc(C(=O)O)cc1 +CCOC(=O)C1(Cc2ccc(OCc3cc(CC(C)C)nc4ccccc34)cc2)CC1C(=O)NO +CNc1ccc(C#CCC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N(C)C2CCCC2)cc1 +Nc1nc2c(s1)Cc1cccc(OP(=O)(O)O)c1-2 +O=C(Nc1cccc(CN2CCOCC2)n1)Nc1cccc2c1C1CCCCN1C2=O +Cc1ccc(N(C(=O)N(C)CCCN2CCC3(CCc4ccccc43)CC2)c2ccc(F)c(F)c2)cc1 +Cc1cc(C)c(NC(=O)C(C)(C)CCCCCCc2ccccc2)c2c1CC(C)(C)O2 +CCCn1nc(C(C)(C)C)c(C(=O)OC)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(N(C)c2nc(SC)nc3ccccc23)cc1 +Cc1cccc2c1N(C(=O)CSc1ncc(C(F)(F)F)cc1Cl)CCC2 +CC(C)(C)CCN1C(=O)C(NC(=O)Nc2ccccc2)C(=O)N(c2ccccc2)c2ccccc21 +COc1ccc(-c2nc(-c3ccc(C(F)(F)F)cc3)oc2Sc2nc3ccccc3s2)c(OC)c1OC +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(-c4csc(C)n4)s3)CC2)nc1 +Cc1ccc(-c2cnc(C3CC3)o2)cc1S(=O)(=O)NC1CCC(O)CC1 +O=C1C(=O)N(Cc2cn(CCF)nn2)c2ccc(S(=O)(=O)N3CCC3COc3cccnc3)cc21 +COc1cccc(CN2CCCC(CNC(=O)c3ccc(F)cc3)C2)c1OC +Cc1nc(C#Cc2ccc(-c3cc(F)cc(C#N)c3)nc2)cs1 +CC(C)CN1CCCC1c1ccc(NC(=O)Nc2ccccc2N2CC(C)(C)c3c(-c4ccc(F)cc4)ccc(O)c32)cc1 +CS(=O)(=O)c1ccc(COc2ccccc2CNCC(O)c2cc(Br)cs2)cc1 +Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1Nc1ncccc1-c1ccncn1 +Cc1cc(N2CCOCC2)nc(N(CCCNc2ccnc3cc(Cl)ccc23)Cc2ccc3c(c2)OCO3)n1 +N=C(c1ccc(C(=O)N2CCN(S(=O)(=O)c3cc4cc(Cl)ccc4[nH]3)CC2)cc1)N1CCCCC1 +CC(C)(C)C(NC(=O)C(Cc1ccc2ccccc2c1)C(O)C(=O)NO)C(N)=O +Cn1c2c(c3cc(S(=O)(=O)n4ccc5ncccc54)ccc31)C1CCC(C2)N1 +NC(=O)C1CC=C(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +Cc1cc(Cc2nc3n(n2)Cc2c(C)ncn2-c2ccc(Cl)cc2-3)on1 +CC1CN(c2cncnc2)Cc2cc(NC(=O)c3cc(CN4CCN(C)CC4)cc(C(F)(F)F)c3)ccc21 +Cc1nn2c3c(cnc2c1S(=O)(=O)c1ccccc1)CNCC3 +CCNC(=O)C1OC(n2cnc3c(NC4CC5CC4C4OC54)[n+]([O-])cnc32)C(O)C1O +O=C1N(Cc2ccc(O)cc2)C(Cc2ccccc2)C(O)CN(S(=O)(=O)c2cccc(Br)c2)N1Cc1ccc(O)cc1 +CCOC(=O)C=C1CC2(CCCC2)CC(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCCN(c2nsc3ccccc23)CC1 +CCN1CCN(c2ccc(Nc3cc(N(C)C(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)ncn3)cc2)CC1 +Cc1oc(C2CCC(C)N(C(=O)c3ccccc3-n3ncnn3)C2)nc1C(C)(C)O +Cc1cc(C)c(=O)n(C(C(=O)NS(=O)(=O)c2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)n1 +CCOC(=O)c1cc(Cc2cccc(Br)c2)c(=O)n2c1CCC2 +CC1C(c2cccc(C(F)(F)F)c2)OC(=O)N1C(=O)NCc1cncc2cccnc12 +CC(N)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 +CC1=C(N2CC2)C(=O)c2nc3n(c2C1=O)CCC3 +CCC(NC(=O)c1c([S+](C)[O-])c(-c2cccc(F)c2)nc2ccccc12)c1ccccc1 +CNS(=O)(=O)c1ccc(OC)c(Nc2cc(Nc3ccc(Cl)cn3)ncn2)c1 +O=C(O)CN1C(=O)C(=O)N(Cc2ccc(Cl)c([N+](=O)[O-])c2)C1=O +O=C(Nc1ccc(OCCN2CCCC2)cc1)Nc1ccc(-c2nc(N3C4CCC3COC4)nc(N3C4CCC3COC4)n2)cc1 +COc1cc2c(cc1OC)-c1n[nH]c(Nc3cc(Cl)cc(Cl)c3)c1C2 +CC(C)(CC(=O)N1CCCC1)NCC(=O)N1CC(F)CC1C#N +Cc1nc(NC(C)c2cccc(-c3ccc(N4CCNCC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +COC1CC(C(=O)N2CCc3nc(C#Cc4ccccc4)sc3C2)C1 +CN(C)c1ccc(-c2cn3c(=O)c4ncn(C5CC(N=[N+]=[N-])C(CO)O5)c4nc3[nH]2)cc1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccccc4)cc3)c(Cl)c2n(CCC)c1=O +COc1cc(OCc2csc(N3CCCC3C)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +CN(C)Cc1ccc(-c2cc(C#N)c(NCc3cnco3)n3cnnc23)cc1 +O=C(CCCCCCn1cc(-c2cccnc2)nn1)Nc1ccccc1Oc1ccccc1 +Nc1nc(N)c2nc(COc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)cnc2n1 +N=C(Nc1ccc2c(c1)N(C1CCNCC1)CC2)c1cccs1 +O=C(Nc1ccc(Cl)c(CN2CCC(C(=O)NC3CCCC3)CC2)c1)c1ccc2ncccc2c1 +CC1CCN(C(=O)C(C)(C)C#N)CC1N(C)c1ncnc2[nH]ccc12 +Cc1ccc(CNCCN2CCCCC2)cc1NC(=O)c1ccc(Nc2ncc(C)c(-c3ccc(OC(F)(F)F)cc3)n2)cc1 +CCCc1nc2c(n1Cc1ccc(-c3ccccc3S(=O)(=O)Nc3onc(C)c3C)c(C)c1)C(=O)CCCC2 +C=Cc1cc(S(C)(=O)=O)cc2c3c(n(Cc4ccc(Cl)cc4)c12)C(CC(=O)O)CC3 +Cc1nn(Cc2ccccc2N(C)C)c(C)c1CC(=O)NCc1ccc(F)cc1Cl +C=CC(=O)Nc1cccc(C(=O)Nc2cccc(Nc3cc(-c4c(-c5ccc(F)cc5)nc(SC)n4C)ccn3)c2)c1C +CN(C)CCOc1ccc(C(=C(CCC(F)F)c2ccccc2)c2ccc(O)cc2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NCC3CCC3)c2cn1)c1ccccc1 +CCOCCC1(Oc2ccc(Oc3ccccc3F)cc2)C(=O)NC(=O)C(N)C1=O +Cc1cnc2[nH]cc(Cc3cnc(NCc4cccc(N5CCOCC5)n4)nc3)c2c1 +CN1CCN(CCCC#Cc2cnn3c(-c4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)ccnc23)CC1 +COc1ccc(-c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)nc1 +COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCC(C(=O)O)CC2)C3=O)c(OC)n1 +Cc1cc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)ccc1C1(O)CCC1 +COc1cc2ccccc2cc1C=NNc1ccnc2cc(Cl)ccc12 +OCC1(NCc2nc(-c3ccc(C(F)(F)F)cc3)ccc2F)CCCCC1 +CCOC(=O)C1=C(CN2CCOCC2)NC(c2nccn2C)=NC1c1ccc(F)cc1Br +Oc1ccc2c(c1)CCC1C2CCC2(O)C(O)CCC12 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(S(=O)(=O)c2ccc(-c3ccccc3)cc2)CC1 +O=C(C=Cc1c(C(=O)O)[nH]c2c1CCCC2)Nc1ccccc1 +Cc1nc2cc(C=CC(=O)NO)ccn2c1CN(C)CC(C)(C)C +CC1CN(C(=O)OC2(C3COCC(CC4CC4)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)CC(C)N1CCO +Nc1nc(NCCNc2ncc(N3CCNCC3=O)c(-c3ccc(Cl)cc3Cl)n2)ccc1[N+](=O)[O-] +CN1CC(C(=O)Nc2nccs2)CC2c3cc(C(C)(C)C)cc4[nH]cc(c34)CC21 +COC1CC(=O)C2(C)C1C(OC(C)=O)CC1C3(C)CCC(O)C(C)(C)C3CCC12C +NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCCc4ccccc4)nc32)CC1 +Cc1cnc(Nc2ccc(C3CCN(C)CC3)nc2)nc1CCc1ccccc1C1(C(N)=O)CC1 +NCCCCCN1Cc2[nH]c3ccccc3c2CC(NC(=O)CC(c2ccccc2)c2ccccc2)C1=O +O=C(O)C1CC1c1ccc(-c2c(C3CC(c4ccc5ccccc5n4)C3)nc3c(N4CCOCC4)ccnn23)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccccc2)CC1 +Cn1c(=O)n(CC2CC2)c(=O)c2[nH]c(-c3cnn(Cc4ccccc4)c3)nc21 +CC(=O)Nc1cccc(-c2ccc(C(=O)N3CCc4c([nH]c5ccccc45)C3c3ccc4c(c3)OCO4)o2)c1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C)c1ccccc1C(=O)N2C +CC=CC=CC=CC[N+](C)(CCCCCCCCCCCCCC)Cc1ccccc1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O +Cn1c(=O)c2c(nc3n2CCCN3Cc2ccc(Cl)c(Cl)c2)n(C)c1=O +O=C(O)C1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(N2CCC(F)(F)C2)cc1F +Fc1ccc2[nH]cc(C3=CCN(CCc4coc5ccccc45)CC3)c2c1 +O=S(=O)(c1ccc(-c2cnc(C3CC3)o2)cc1)N1CCOc2ccccc21 +O=C(NC1(CO)CC1)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CC(C)(NS(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1)C(F)(F)F +O=C(O)C=Cc1ccc(C(=C(c2ccccc2Cl)C2CCC2)c2ccc3[nH]nc(F)c3c2)cc1 +N#Cc1cnc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)nc1OC1CCOC1 +CCc1cc2c(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3F)ccnc2cc1OC +NCCNC(=O)c1cncc(-c2cnc(Nc3cc(N4CCOCC4)ccn3)s2)c1 +CCC(C)Sc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br +O=C(O)Cn1c2c(c3c(F)cc(F)cc31)CCN(Cc1ccccc1)C2=S +CCCCOc1ccc(S(=O)(=O)N(CCc2cccs2)Cc2c[nH]cn2)cc1 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(Br)cc2)nc1 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CC6CCC(C5)N6C)ccn34)c12 +ON=Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5c(c4)OCCO5)CC3)c2c1 +Cc1ccc(-c2ncn3c2C(C)(C)N(C(=O)N(C)C)c2ccccc2-3)cc1 +O=C(Cn1cc(-c2cccnc2)nn1)Nc1ccc(-c2ccccc2)cn1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)CN)c12 +Cc1n[nH]c2c1C(c1ccccc1I)C(C#N)=C(N)O2 +N=C(N)c1cccc(N2CC(COCc3ccccc3)CN(CC3CCN(Cc4ccccc4)CC3)C2=O)c1 +COc1cc(-c2cn[nH]c2)ccc1C(=O)NC(C)c1ccc(F)cc1 +CNC(=O)Cn1cnc2ccc(-c3cccc(OCC(O)CN4CCc5ccccc5C4)c3)cc21 +Cc1cc(-c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)ccn1 +CC(C)(O)CNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CC(C)(C)NCc1cc(Nc2ccnc3cc(Cl)ccc23)cc(C2CCCCC2)c1O +COc1ccccc1Oc1ncccc1C(=O)NCC(O)CN1CCN(c2ccccc2OC)CC1 +CCOC(=O)c1ncn2c1CN(C(C)=O)c1ccccc1-2 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cc(NS(C)(=O)=O)cc(C(C)(C)C)c2)CCCCC1 +O=C(COc1ccc(Cl)cc1)NNC(=S)NCc1ccccc1-c1ccccc1 +COc1c(-c2nc3ccccc3[nH]2)c(O)cc2oc(C)cc(=O)c12 +Cc1cc(C(=O)NCC2C(C(=O)Nc3ccc(Br)cc3)C3C=CC2C32CC2)nn1C +CS(=O)(=O)N(Cc1ccncc1)c1ccc(Nc2ncc3cnn(C4CCCCCC4)c3n2)cn1 +Cc1nc(NC(C)c2cccc(-c3cnc(N4CCN(C)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CN(C)C(=O)Oc1ccc(CC(Nc2nc(N(C)C3CCCCC3)nc3ccccc23)C(=O)O)cc1 +O=C1N(c2ccccc2)C(CCc2ccccc2)C(O)C(Cc2ccccc2)N1c1ccccc1 +CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1c(F)cc(F)c(F)c1F +CC(O)c1cc(C(=O)NC(C)c2ccccc2F)ccc1-c1cn[nH]c1 +OC(c1ccc(Cl)cc1)(c1ccc(C(F)(F)F)cc1)c1cccnc1 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3ccc(N)c(Br)c3)C2O)c1 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+O=C(Nc1ccc2[nH]cc(C3CCN(Cc4ccccc4)CC3)c2c1)c1ccc(F)cc1 +COc1ccc(C(Cc2ccncc2)c2cccc(OCc3ccccc3)c2)cc1OC1CCCC1 +CCNC(=O)OCc1c(COC(=O)NCC)c2sc3ccccc3n2c1-c1cc(OC)c(OC)c(OC)c1 +CN1CCN(c2cc(Nc3cc(C4CC4)n[nH]3)nc(NCc3cc(-c4ccc(F)cc4)no3)n2)CC1 +COc1cccc(NC(=O)c2ccc(N3CCCCC3)c([N+](=O)[O-])c2)c1 +Cc1ccc(C(=O)N2c3ccccc3C(Nc3ccccc3)CC2C)cc1 +Cc1cccc(CN2CCN(c3ccccc3OC(C)C)CC2)c1 +Cn1cc(N(Cc2ccccc2)c2ccc(C#N)cc2)cc1C(=O)N1CCCC1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc4nnnn4n3)c2)c2cncnc21 +O=C(c1nc2sc3c(n2c1Cl)CCCCC3)N1CCN(C2CCCC2)C(=O)C1 +CCc1ncnc(NC(C)c2ccc(OC(=O)NCCCOCCCNC(C)=O)cc2)c1Cl +c1ccc2[nH]c(-c3ccc(OCCCOc4ccc(-c5nc6ccccc6[nH]5)cc4)cc3)nc2c1 +COc1ccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3S(=O)(=O)C4)CC2)cc1 +COc1cccc(-c2ccc3c(c2)C2(COC(N)=N2)C2(COC2)C2(CCC2)O3)c1F +COc1ccc(Nc2nc(N3CCCC(C(=O)Nc4ccc(C(=O)O)cc4)C3)nc3scnc23)cc1OC +CCC1CCNc2cc3c(cc21)c(C(F)(F)F)cc(=O)n3C +COc1ccc2ccc3c(c2c1)CC(N)C(c1ccccc1F)O3 +CC(=O)NN=CC(C)(C)C1CCC2(C)C(CCC3C4C5OCC4(CCC5(C)C)CCC32C)C1(C)CC#N 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+CCCCCCn1c(=O)c(C(=O)Nc2ccc(C(=O)O)cc2)c(O)c2ccccc21 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4C)no3)ccc21 +CN(C)CCNc1ccc2nc3c4c(nccc4c2c1)-c1ncccc1C3=O +Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CC1CCCCC1 +O=C(O)c1ccc(CCC2C(=O)CCC2C=CC(O)Cc2ccc(F)cc2)cc1 +CC(Cc1c[nH]c2ccccc12)NCC(O)c1cccc(NS(=O)(=O)c2cccs2)c1 +O=C(NN1CC=C(c2ccc3[nH]cc(CCN4CCCC4)c3c2)CC1)C1CCCCC1 +CC12CCCC(C=CC(=O)NS(=O)(=O)c3cc(F)cc(F)c3)=C1N(Cc1ccc(F)c(F)c1)C(=O)C2 +Cc1nc(-c2cccc(C(=N)N)c2)c(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)s1 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C)nc2C(O)C(C)C)n1 +Fc1cc(F)cc(Nc2nccc(-c3c(-c4ccccc4)nn4ncccc34)n2)c1 +NCC1CN(c2ncnc3[nH]c4cnccc4c23)CCO1 +O=C1N(Cc2ccccn2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +Cc1ccc(C(=O)c2sc3[nH]c(=O)c(C(=O)O)cc3c2N)cc1 +Fc1ccc(-c2nn3ncccc3c2-c2ccnc(Nc3ccc4c(c3)OCCO4)n2)cc1 +COc1cc2nc(N3CCN(C(=O)C=CC(=O)c4ccccc4)CC3)nc(N)c2cc1OC +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)O +COc1nc(N2CCOCC2C)c2ccc(-c3ccc(OC)c(CO)c3)nc2n1 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+CC(=O)Nc1ccc(Sc2nc(Nc3cc(C)[nH]n3)cc(C)c2C#N)cc1 +O=C(O)c1[nH]c2ccc(Br)cc2c1CCN1C(=O)c2cccc([N+](=O)[O-])c2C1=O +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2cc(N3CCCCC3)ccc2o1 +CCCCNc1ccc(-c2c(N)nc(N)nc2CC)cc1[N+](=O)[O-] +N#Cc1ccc2oc(NC(CC3CCCCC3)c3ccccc3)nc2c1 +Cc1cc(C(=O)Nc2cc(C(=O)c3ccc4c(C=Cc5ccccn5)n[nH]c4c3)ccc2C)n(C)n1 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1N(C)C +CC1CC(=O)C(O)C2(O1)OC1CC(=O)OC1C1=C2C(=O)c2c(O)cccc2C1=O +O=C1NCCCCC1N(CCCCc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OCC[N+](C)(C)C)cc2)C1O +CNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(F)cc4)ccc3C)CC2)ncn1 +CCCn1c2ccc(NC(=O)Nc3ccc(SC)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(CNC(=O)C2CC2)cc1 +Cn1ccc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cccc(F)c2)C(N2CCC2)CC3)c1 +N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)NCc3ccccc3C(=O)O)c(Cl)c2)cc1 +O=C1OCCc2cc(C3CN4CCN(C(=O)Cc5cnc(-n6cnnn6)cn5)CC4CO3)ccc21 +COc1cc(F)ccc1N1CCN(CCC(=O)c2cc(C)sc2C)CC1 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+COc1ccc(S(=O)(=O)N2CC(C(=O)N3CC(CN)C3)c3ccccc32)c2ccccc12 +CC(=O)N1CCC(OC(N)=O)(c2ccc(CN3C(C)CCC(c4ccccc4)S3(=O)=O)c(F)c2)CC1 +C=C(C)N1Cc2cccc3[nH]c(=S)n(c23)CC1C +COc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nsc(O)n2)cc1 +CNc1ccc(C=Cc2ccc(-c3nc4ccc(OCCCF)cc4o3)cc2)cc1 +CN1CCCC1Cn1nc(CC2CCCCC2)c2ccccc2c1=O +Cc1cccnc1CN1CCC(Oc2ncnc3c2ccn3Cc2ccccc2)CC1 +CC1(C)CN=C2C(=O)C(O)=C2N(CCP(=O)(O)O)C1 +O=C(Nc1cccc(Cl)c1N1CCN(Cc2ccco2)CC1)c1ccc(Br)o1 +CC(Oc1nc2c(c(Nc3ccc(S(=O)(=O)N4CCCC4)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2)C1CC1 +C#Cc1ccc2c(c1)C(=O)N1CCC1c1c(-c3nc(CC)no3)ncn1-2 +CCOC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1-c1ccc(C)s1 +Cc1ccc(C(=O)NC2CCN(C3CCC(N(C)C(C)C)CC3CS(C)(=O)=O)C2=O)cc1C(F)(F)F +CN1Cc2cccc(Oc3nc(Nc4ccc(OC5CCOCC5)cc4)ncc3C(F)(F)F)c2C1=O +CC1OC(=O)N2CC(c3nc(-c4ccc(C(=O)Nc5cc(C6CC6)ccn5)cc4)c4c(N)nccn34)CCC12 +FC(F)(F)c1cccc(C(F)(F)F)c1-c1ccc2[nH]c(C=CC3CCCCC3)nc2c1 +CC(C)NC(=O)OCC1OC(n2cnc3c(NC4CCOC4)ncnc32)C(O)C1O +NC(=O)Cc1ccccc1-c1ccc(COC2CCC(N3CCCCCC3)C2OCC=CCCC(=O)O)cc1 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+O=[N+]([O-])c1ccc(C[n+]2ccc(-c3cc4cc(Br)ccc4o3)cc2)cc1 +O=C(CCCCOc1ccc(-c2cc(=S)ss2)cc1)NO +CC1CCC2C(CN=[N+]=[N-])=C(C(F)(F)F)OC3OC4(C)CCC1C32OO4 +CC(C)C(NC(=O)C(CC(=O)O)NC(=O)CNC(=O)COc1ccc(C(=N)N)cc1)C(=O)O +CN(CC1=Nc2c(N)nc(N)nc2NC1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +O=C1C2Cc3ccccc3CN2C(=O)N1CCCN1CCCCC1 +Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCNc1c3c(nc4ccccc14)CCCC3)O2 +COc1ccc2c(c1F)C(=O)N(CC1(C#Cc3ccc(C4(O)CCNCC4)cc3)NC(=O)NC1=O)C2 +COc1ccc(CNc2nc(N3CCC4(CC4)C3)ncc2C(=O)NCCN2CCOCC2)cc1Cl +COc1c(C(C)Nc2ncnc(N)c2C#N)cc(Cl)c(F)c1-c1cncc(C#N)c1 +COc1cc(C2C(C#N)=C(N)Oc3c2ccc2c3CCCC2)cc(Br)c1OC +CC(C)CC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NO +Fc1ccc2[nH]c3c(c2c1)CN(CCCCc1ccncc1)CC3 +O=C(c1nn(Cc2cc(Cl)cs2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CC(=O)N1CCC(C(=O)N(CCCN2CCC(CNC(=O)c3ccsc3)CC2)c2ccc(C)c(Cl)c2)CC1 +O=C(c1ccc(F)cc1)C1CCN(C2CCCCC2O)CC1 +CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCN(C)C)nc3)c2n1 +OC1(c2ccccc2)CCN(C(c2ccccc2)c2ccccc2Br)CC1 +CC1NC(C(=O)N2CCCC2C#N)CC1C(=O)N1CCOCC1 +CCOC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1ccco1 +COc1ccc(SCc2cnc(SCc3c(F)cc(C(=O)NCCS(=O)(=O)O)cc3F)n2-c2ccc(F)cc2)cc1OC +COc1cc(OC)cc(N(CCCN)c2ccc3ncc(-c4cnn(C(C)C)c4)nc3c2)c1 +CNCC(C)c1ccc(-c2c(O)cc(C)c3[nH]c(=O)c4sccc4c23)cc1F +COc1cccc(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)c1N +Cc1ccc(-c2nc3c(Cl)cc(Cl)cc3c(=O)n2O)cc1 +Cn1ncc(NC(=O)c2ccc(F)c(-c3cccc(F)c3Cl)n2)c1C1CCC(N)C(F)CO1 +O=C(O)Cc1sc(-c2ccccc2)nc1-c1ccc(Cl)cc1 +CC12CCN(C(=O)C3C4CC5CC(C4)CC3C5)C(Cc3c(O)cccc31)C2(C)C +COc1cccc(N(C)C(=O)c2ccc(-c3ccccc3)s2)c1 +CCc1cc(=O)oc2nc(OCc3ccccc3)[nH]c(=O)c12 +Nc1ccc(-c2cnc(NC(=O)CN(Cc3ccccc3)C(=O)c3ccncc3)s2)cc1 +O=C(Nc1ccc(S(=O)(=O)C2CCCCC2)cc1)c1ccc([N+](=O)[O-])o1 +[C-]#[N+]c1ccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 +CC(=O)c1ccc(Cl)cc1OCC1CN(Cc2ccc(Cl)cc2)CCCO1 +CCCCC1=NCC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +NC(CC(=O)N1CCCC1CNc1ncccn1)Cc1cc(F)c(F)cc1F +COc1cccc2sc(C3(NC(=O)CC(N)Cc4ccccc4F)CCS(=O)(=O)CC3)nc12 +O=C(CNCc1ccc(Oc2ccccc2)cc1)Nc1ccc2ccn(CCN3CCCC3)c2c1 +Cc1cc(Oc2ccc(C(=O)NC3CN(C(=O)OC(C)(C)C)CC3C(=O)NO)cc2)c2ccccc2n1 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ncc(F)cn2)CC1c1ccc(F)cc1 +O=C(CNCCO)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 +COc1ccc(Nc2nc3c(NC4CCN(S(C)(=O)=O)CC4)cccn3n2)cc1 +O=C(O)CC1CCC(c2ccc(-c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)cc2)CC1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(-c3cc(CO)co3)c2c1=O +CCSCC1CC(O)(c2ccccc2)C(c2ccccc2)C(c2ccc(Br)cc2)O1 +COc1ccc(F)c(-c2cc(C)c(Nc3ccc(C)cc3C(=O)O)cn2)c1 +CS(=O)(=O)NC1CC2CCCCC2C1C=Cc1ccc(-c2cccc(F)c2)cn1 +CCN1CCN(CC)CC(NC(=O)c2cc(Cl)c(NC)nc2OC)C1 +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(NC(=O)Nc3ccccc3F)CCc3ccccc32)c1 +CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c-2c1COC +[H]C(O)C1NC(c2c[nH]c3c(=O)[nH]cnc23)C(O)C1O +Cc1c(N(Cc2ccc(-c3ccccc3)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(OCC(F)(F)F)c1 +Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CCO)c5)cnc(N)c34)cc2F)c1 +O=Cc1c(O)ccc2cc(-c3ccc(C(=O)O)cc3)ccc12 +COc1cc(-c2ccc(Cl)c(F)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(O)CN1CCN(c2ccc(Nc3ncc4ccc(-c5ccccc5N(C)S(C)(=O)=O)n4n3)cc2F)CC1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CCNCc1ccccc1 +N#Cc1cccc(-c2ccc3c(c2)C2(CCCCC2)C(=S)N3)c1 +CCN(CCCCCSc1nc(-c2ccc(SC)cc2)c(-c2ccccc2)[nH]1)c1nc2ccccc2o1 +CCC(=O)Nc1cccc(Nc2cc(Nc3cccc(Br)c3)ncn2)c1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCN(C)CC3)cc2c1=O +FC(F)(F)Cc1nnc2c(Cl)c(N3CCC(c4ccccc4)CC3)ccn12 +NS(=O)(=O)Oc1ccc(NC(=O)Nc2ccc(Cc3ccccc3)cc2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCS(=O)(=O)CCC1OCCC2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OCC12 +COc1ccc2c(c1)CCN1C(=O)C3CCCC(C21)N3S(=O)(=O)Nc1ccc(N2CCOCC2)nc1 +COCCN1CC(C)(C)Oc2nc(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)Nc4ccon4)cc3)c2C1=O +CCN(Cc1ccccc1)C(=O)C1(c2ccccc2)CC1CN +CCCSc1nc(NC2CC2c2ccc(F)c(F)c2)c2nnn(C3C=CC(O)C3O)c2n1 +CCCc1ccc(-c2ccc(N(CC3(N)CCCC3)C(=O)C3CC3c3cccc(F)n3)cc2)cc1 +O=C1C=C(c2cccc([N+](=O)[O-])c2)c2ccccc2C1=O +CC1C(=O)N(CCOCc2ccccc2)CCCN1C(=O)CC(N)Cc1cc(F)c(F)cc1F +COCc1cccc(NS(=O)(=O)c2ccc(C)c(N3CCNCC3)c2)c1 +Cc1ccc(-n2nccn2)c(C(=O)N2C3CCC2C(COc2ccc(C(F)(F)F)cn2)C3)n1 +CCN(CC)CCNC(=O)c1ccc(C(CC)(CC)c2ccc(C#CC(O)(CC)CC)c(C)c2)n1CC +CN(C)CCc1cccc2[nH]c(-c3nc(CCC4CCCC4)no3)cc12 +COC(C)C(=O)N1CCN(c2ccc(CN(CC(C)C)S(=O)(=O)Cc3ccccc3)cc2)CC1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1cccc(Cl)c1Cl +FC(F)(F)c1ccc(-c2ccc3ncc(-c4ccncc4)n3n2)cn1 +CCCCCN(CCCCC)C(=O)Cc1coc(-c2ccccc2)n1 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cccc(-c4ccncc4)c3)o2)c1 +Nc1ccc(-c2ccc(-c3ccccc3S(=O)(=O)NC(c3ccccc3)C(F)(F)F)cc2F)cn1 +CCC(C)C(=O)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +O=C(O)c1cn(Cc2ccc(S(=O)(=O)F)cc2)c2ccccc2c1=O +CNC(=O)c1cc2ccc(CCNC(=O)Nc3cc(C(F)(F)F)ccc3OC)cc2cn1 +CN(C)Cc1cc2c(nc1C=O)N(C(=O)Nc1ccc(C#N)cn1)CCC2 +CC(=CCc1ccccc1)CCC(=O)CC1CC(O)CC(C)=CCC=CCC(CC(=O)O)=CC(=O)O1 +CC(=O)N1CCC(Oc2cncc(-c3cnc4c(c3)CCCN4C(C)=O)c2)CC1 +COc1ccc(OC)c(-c2cccc3c(N)c(C(=O)NCCC(F)(F)F)nnc23)c1 +CCOC(=O)C(C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(C)c12 +c1ccc(CCNc2nc(-n3ccnc3)nc3ccccc23)cc1 +CCCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1nc(C)c(CC)c(=O)[nH]1 +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NC1CCC(O)(c2ccnn2C)CC1 +Cc1c(N2C(=O)OCC2C(O)C(F)(F)F)ccc(C#N)c1Cl +CCc1ccc(NS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +CCNC(=O)C1OC(n2cnc3c(N)nc(NCCc4ccc(F)cc4)nc32)C(O)C1O +CC1CCC(Oc2cccc3ncccc23)CN1C(=O)c1ccccc1-n1nccn1 +Cc1ccc(N2CCN(CCNC(=O)c3ccc(F)cc3)CC2)cc1 +Cc1ccc(SCC2NC(c3c[nH]c4c(N)ncnc34)C(O)C2O)cc1 +CCc1c(C(=O)NCc2ccc(Cl)c(Cl)c2)nn(-c2ccc(Cl)cc2Cl)c1-n1cccc1 +O=C(NS(=O)(=O)C1CC1)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1 +Clc1cccc(Nc2cncc(-c3cncc(NCCCN4CCOCC4)c3)n2)c1 +Cc1ccc(NC(=O)c2ccncc2C(C)(C)C)cc1Nc1nc2ccccc2n1-c1cc(N)ncn1 +O=C(N1CCCCC1)N1CC(OC(c2ccc(Cl)c(Cl)c2)c2cccnc2Cl)C1 +CCN(CC)CC(c1c(F)cccc1F)N1CCN(C)CC1 +O=C(c1ccc(Br)cc1NS(=O)(=O)c1sc(Cl)cc1Br)N1CCCCC1 +c1cc(C2=NC3(CCCCC3)CO2)ccc1OC1CC(N2CCCCC2)C1 +COCCN(CC1CC1)c1c(OC)nn2c(-c3c(OC)cc(COC)cc3OC)csc12 +CCCOc1ccc(S(=O)(=O)N2CCN(c3ccccc3)CC2)cc1-c1nc(C(C)C)c(Br)c(=O)[nH]1 +COC(=O)C1CC(OC2CCCO2)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +CCCCCCC(C)(C)c1cc(O)c(-c2cc(C)cc(C)c2)c(O)c1 +Cc1ccc(NC(=O)c2ccc3c(c2)CCC3N2CCN(CCO)CC2)cc1Nc1nccc(-c2cccnc2)n1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCc4nocc4C3)[nH]c12 +Cc1cc(Oc2ccccc2S(=O)(=O)NC(C=O)C(=O)O)ccc1C(C)C +CCCCCOc1ccc(C(=O)NCCc2ccc(N)cc2)cc1SCCCCC +O=C(c1ccc2nc[nH]c2c1)N1CCCC2c3cccc(O)c3CCC21 +Cn1cc(-c2cnc3nnn(Cc4cc5cccnc5s4)c3n2)cn1 +CCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +Cc1onc(-c2ccccc2)c1COc1cc(OCc2ccccc2)ccn1 +Cn1c(OCCNc2ccccc2)nc(-c2ccncc2)cc1=O +NCCCNCCCCNCCCNC(=O)Cc1cccc2ccccc12 +COc1ccc(CC2C(O)C(O)C(Cc3ccc(OC)cc3)N(CC3CC3)C(=O)N2CC2CC2)cc1 +CNc1nc(C2CC2)c(-c2ccnc(Nc3ccc(S(N)(=O)=O)cc3)n2)s1 +CCC(C)(C)C(=O)Nc1n[nH]c2nc(N3CCCCC3)c3c(c12)CCN(Cc1ccccc1)C3 +CCc1ccc(-c2ccc3c(n2)C(=O)N(c2ccc(OCCN4CCCC4)c(OC)c2)C3)cc1 +COC(=O)c1ccc(-c2nnn3c2CN(C(=O)CC(N)Cc2cc(F)c(F)cc2F)CC3)cc1 +O=C(Cc1ccc(O)cc1)NN=C1C(=O)Nc2cccc(-c3ccc(F)cc3)c21 +Cc1c(CC(=O)O)c2cccnc2n1C(C)c1ccc(C(F)(F)F)cc1 +Cc1cccc(C(=O)NCC(c2ccc(Cl)cc2)N2CCC(F)(F)CC2)c1C +CC(C)Nc1nc(Nc2ccccc2)nc(Nc2ccc(Cl)cc2)n1 +COC12CCC3(CC1C(C)(C)O)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +O=C(O)CNC(C(=O)N1CCCC1C(=O)NCC#Cc1c[nH]cn1)C(c1ccccc1)c1ccccc1 +CC1CCCC(=NNc2nc(-c3ccc([N+](=O)[O-])cc3)cs2)C1 +CC(C)CC(NC(=O)CCCCC1CCSS1)C(=O)NC(Cc1ccc(Br)cc1)C(=O)C(=O)NCCc1ccccn1 +CS(=O)(=O)c1ccc(CNc2nccn3c(-c4ccc(O)cc4)cnc23)cc1 +CC(C=CC1=C(C)C(n2ccnc2)CCC1(C)C)=CC=CC(C)=CC(=O)O +Cc1nc2c(cnn2-c2ccccc2)c(=O)n1-c1ccc(Br)cc1 +CS(=O)(=O)NCCCCCNc1nc2c(s1)CCCc1ccc(F)cc1-2 +O=C1C=Cc2c(c(-c3ccccc3)cn2S(=O)(=O)c2ccccc2)C1=O +CCc1ccnc(C#CCN(c2cc(OC)cc(OC)c2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)n1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC1CCOCC1 +Cc1cn2cc(-n3ccccc3=O)cc(NCc3c(C)cccc3C)c2n1 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2sc(-c3ccc(C(=O)O)cc3)cc2c1 +O=c1cc(-c2ccn3c(-c4ccccc4)cnc3c2)ccn1CCCO +COc1cc(C(C)NC(C)c2cccc(Cl)c2)nn1-c1ccc(Br)cc1 +C=CCOC1(c2ccc(Br)cc2)SC=C(C)n2c1noc2=O +Cc1cc(C)c(S(=O)(=O)NC(C)CNc2cccc3c2cnn3-c2ccc(F)nc2)c(C)c1 +COCCCCn1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)c2c(F)ccnc21 +COc1ccc2[nH]nc(-c3cc(N4CCOC(C)C4)ncn3)c2c1 +Cc1nnc(SCCCCOc2c3ccoc3cc3oc(=O)ccc23)s1 +CNC(=NS(=O)(=O)c1ccc(Cl)cc1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1 +COc1ccc(Br)cc1CN(c1sc2ccccc2c1Br)S(=O)(=O)c1ccccc1 +COC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n(C2CCCC2)c1=O +COc1cc2c(cc1OC)CN(C=Nc1ccc3c(c1)C(OC(C)=O)CCC3)CC2 +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3ccccc3)ccc21 +O=C1c2ccccc2C(=O)c2c(NCCCO)nnc(NCCCO)c21 +O=C(O)C=Cc1ccc(NC(=O)C2(NC(=O)c3ccc4c(c3)nc(-c3ccoc3)n4C3CCCCC3)CCC2)cc1 +Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)NC(C)C)cc1 +[C-]#[N+]c1ccc2c(c1)C1(N=C(C)C(N)=N1)C1(CCC(OC)C(C)C1)C2 +CC(C)c1nc(OCc2ncon2)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1 +c1cc(-c2n[nH]c3cnc(-n4ccnc4)cc23)nc(N2CCNCC2)c1 +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3cc(-c4cccc5ccccc45)[nH]n3)CC2)C(c2ccccc2)C1 +O=C(C=Cc1ccc(O)c(O)c1)OCC(OC(=O)C=Cc1ccc(O)c(O)c1)c1nnn[nH]1 +CCOC(=O)C#Cc1c(C(=O)OCC)nnn1C1OC(CO)C2OC(C)(c3ccccc3)OC21 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCN1C(=O)CCC1=O +COC(=O)C1=C(Nc2ccc(Cl)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O +Cc1cnc2c(c1)N=C(N1CCN(C)CC1)c1ccccc1N2 +COc1cc2oc(C(=O)NCCCCCCCCCCNc3c4c(nc5ccccc35)CCCC4)cc(=O)c2cc1OC +CCN(Cc1ccccc1)C(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +O=C(O)C1CCCN(S(=O)(=O)c2ccc3cc4ccccc4cc3c2)C1 +CC12CCC3C(CC(Cc4ccccc4)C4=CC(=O)CCC43C)C1CCC2=O +Cc1cc(C(=O)O)nc(N2CC3CC(c4cccc(F)c4Cl)CC3C2)n1 +CCC(c1ccc(C(=O)O)c(Oc2cccc(Cl)c2)c1F)N1CCCC(n2cc(C)c(=O)[nH]c2=O)C1 +Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCCC1CCN(C(=O)CCN2CCCCC2)CC1 +Cc1nc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)cs1 +O=C(CCS(=O)(=O)c1ccc(Oc2ccncc2)cc1)NO +Cc1c(-c2ccc(C#N)cc2)nc(N)nc1N1CCN(C)CC1 +O=C(NCC1(C(=O)N2CCCCC2)CCCC1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CC(C)(Oc1ccccc1)C(=O)NCC(O)CN1CCc2ccccc2C1 +O=S(=O)(Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F)c1cccc(F)c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)Cc1n[nH]c3ccccc13)CC2 +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1OP(=O)(O)O +OC1(c2ccc3c(c2)OCO3)CCC(N2CCN(Cc3cccc(F)c3)CC2)CC1 +Cc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)NCCCCCCCNc1c2c(nc3ccccc13)CCCC2 +CCC(CC)Cc1ccc(OCCN(C)C(=O)OC(C)C)cc1 +COCC(NC(=O)Nc1cc2[nH]nc(-c3ccc(C(F)(F)F)nc3)c2cn1)c1ccc(F)cc1 +CC(C)(O)c1cccc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)n1 +CCCN1CC(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2NCCN(Cc3ccccc3)C2=O)N(C(C)C)C1=O +Cc1ncc(C)n2nc(CCc3nc(N4CC(F)C4)nn3C)nc12 +COc1cc2c(cc1OC)C(=O)C(=Cc1cc(C)c(N)c(C)c1)C2 +CCOC(=O)N1C2CCC1CC(c1ccnc3c(-c4ccc5cc[nH]c5c4)c(-c4ccncc4)nn13)C2 +CC(=O)c1nn(CC(=O)N2C(C(=O)NCC3CC3(Cl)Cl)CC3CC32)c2ccc(OCc3ncccc3F)cc12 +NC1=NC(CCc2ccc(Nc3ncc(C4CCC4)cn3)cc2)CO1 +N#Cc1ccc2nc(Nc3ccc(-c4ccccc4)cc3)[nH]c2c1 +Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(-c4ncccc4F)c(Cl)cc3Cl)n(-c3ccccc3)n2)ccn1 +Cc1ccc2c(=O)n(-c3ccccc3)c(C(C)Nc3ncnc(N)c3C#N)nn12 +CC1CN(c2cccc(C(=N)N)c2)C(=O)N(C2CCN(Cc3ccccc3)CC2)C1 +CC(C)(F)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1Nc1cnn(C(F)F)c1 +O=C(CC1CCCCC1)Nc1cccc(OCCCN2CCOCC2)c1 +CCOC(=O)Nc1ccc(Nc2ncnc3cc(OCCN4CCCCC4)c(OC)cc23)cc1C +CCCCCCCCNC(=O)C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)NC(=O)C1CCC(CN)CC1 +Cc1ccc(F)cc1Nc1nc2ccc(N(C)C(=O)C=CCN(C)C)cc2n2cncc12 +CC(C)N(C)Cc1ccn2c(-c3ccnc(NC(C)(C)C)n3)c(-c3ccc(F)cc3)nc2c1 +CC(=O)N1CCN(c2ccnc(-n3ccnc3)n2)C(CC(=O)NCc2ccc3c(c2)OCO3)C1 +COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)c(F)c1 +CC(C)COCCCNC(=O)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +OCC(CO)c1ncc(-c2cc(F)cc3c2-c2ccccc2C3(O)C(F)(F)F)o1 +N#Cc1ccc(-c2ccc3cc(CCN4CCCC4CF)ccc3c2)cc1 +O=c1[nH]c2ccc(OC3CCN(c4ccccc4)CC3)cc2c2c1CSCC2 +COc1ccc(-c2nn3c(NC4CCCC4)cccc3c2-c2ccnc(NC3CCCC3)n2)cc1 +CNc1nn2c(NC)cc(C)nc2c1S(=O)(=O)c1ccccc1 +CCN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(Cl)cc2)[nH]c2ccccc12 +CN(C(=O)C=Cc1ccoc1)C1CCC2(O)C3CC4=C(CC(O)CC4)C2(CCN3CC2CC2)C1 +COc1ccc(C2Cc3cc(Cl)ccc3N(CCN(C)C)C(=O)C2C)cc1 +Cc1nc2sc(-c3ccc(F)cc3)nc2c(=O)[nH]1 +O=C(CN1CCN(c2ccnc(NCCc3ccc(Cl)cc3)n2)CC1)N(Cc1ccncc1)CC1CCCO1 +CCCN(CCc1c[nH]c2ccccc12)Cc1ccc(C=CC(=O)NO)cc1 +COCCCc1cc(Br)cc(CN(C(=O)C2CNCCC2c2ccn(C)c(=O)c2)C2CC2)c1 +O=C(NC(Cc1ccccc1)CN(Cc1cnc2ccccc2c1)CC(Cc1ccccc1)NC(=O)OCc1nccs1)OCc1cncs1 +CN(C)CCCNC(=O)c1ccc2[nH]c(=O)c3sc4cc(Br)ccc4c3c2c1 +CC(c1ccc2ncccc2c1)c1nnc2ccc(-c3ccc(S(C)(=O)=O)cc3)nn12 +CC(O)(C=Cc1cccc([N+](=O)[O-])c1)CCC1C(C)(O)CCC2C(C)(C)CCCC21C +Cc1cc(F)ccc1C1CC(NC2CC2)CCN1C(=O)N(C)C(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cn1c(N2CCNC(c3ccc(C#N)cc3)C2)nc(-c2ccncn2)cc1=O +Fc1cccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)c1 +CCc1ncnc(-c2ccc(C(=O)N3CCC4(CCN(C)C4)C3)c(OC)c2)c1C#Cc1ccc(N)nc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NC(C)C(=O)NC1C(=O)N(CC(N)=O)Cc2ccccc2C1C +CCOC(=O)C(O)=CC(=O)c1cn(Cc2c(F)cccc2F)c2cccc(OC)c12 +CCOC(=O)c1c(-c2cccc(-c3ccccc3)c2)[nH]c2cc(OC)c(Cl)cc2c1=O +CNc1cc(Oc2ccc(NC(=S)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2F)ncn1 +CNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC(C)C)ncc1Cl +CSc1cccc(Nc2nc(N)c(N=O)c(OCC3CCCCC3)n2)c1 +CC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(C(F)(F)F)n3)CC3CC32)c2cnccc12 +Cc1cccc(C)c1Nc1ncc(-c2ccc(CN3CCCC3)s2)n2cncc12 +O=C(c1ccc(-c2ccc(O)cc2)o1)N1Cc2c(nc3ccccc3c2O)C1c1ccc2c(c1)OCO2 +CC(O)C#Cc1c(N)ncnc1NC(C)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CCOC5)c4)ccn23)c1 +COc1ccc(N2CC(CN3CCC(O)(c4ccc5c(c4)OC4(CCCC4)O5)CC3)OC2=O)cc1 +O=C(C=Cc1ccccc1Cl)NC1(C(=O)NC(Cc2ccccc2)C(=O)NCC2CCN(CC3CCOCC3)CC2)CCCC1 +CON=Cc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccn3)c2c1 +O=C(Nc1cc(OC(F)(F)F)cc(-c2cccnc2)c1)N1CCc2ccc(CO)cc21 +Cc1ccc(C)c(Nc2nc(NCc3ccco3)c3ccccc3n2)c1 +COC1CCN(c2n[nH]c3cc(NC(=O)NC(COC(F)F)c4ccccc4)ncc23)CC1 +CC(C)CCN(CC(=O)NO)C(=O)N1CCCC1C(=O)Nc1ccc2c(c1)OCO2 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)cc1F +COc1cccc(OC)c1C1CCC(=O)N1Cc1cccc(-c2ccccc2)c1 +N#Cc1ccc(Cn2cncc2CNC2CCN(c3ccccc3Cl)C2=O)cc1 +CC(NC(=O)C1(NC(=O)c2ccno2)COC1)c1ncc(-c2cc(Cl)cc(Cl)c2OCC(F)F)cc1F +COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1 +CN(CCN)C(=O)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(CCCCCCC(=O)c1ccc(-c2ccccc2)cc1)NO +COc1ccc(S(=O)(=O)N(CC(O)CN2C(=O)C3(CCCCC3)OCC2Cc2ccccc2)CC2CCCC2)cc1 +O=C(Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3sccc3n2)cc1)Nc1cccnc1 +CN(C)C(=O)Nc1ccccc1-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1 +COc1cc(C=CC(=O)NCCCNc2c3c(nc4ccccc24)CCCC3)ccc1OCCO[N+](=O)[O-] +COc1ccccc1N1CCN(CCCCC(=O)NC2CCCc3c(OC)cccc32)CC1 +CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(Cl)cc3)C2=O)c(F)c1 +CCCn1c(=O)c2nc(-c3cc(NC(=O)Cc4ccc5c(c4)OCO5)nn3C)[nH]c2n(CCC)c1=O +CN(C)c1ncnc2c1nc(N(C)C)n2Cc1cccc(NC=O)c1 +CCCCCc1nc2cc(C=CC(=O)NO)ccc2n1CCNC(C)C +Cc1cnc2cccc(OCc3c(C)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(N5CCCC5=O)cc4)c3C)c2n1 +CCOC(=O)NC1CCC(NC(=O)c2cc(-c3ccnc(OC)c3)n3ncnc(N)c23)CC1 +CNCC(=O)NC(c1cc(Cl)ccc1N1CCN(C(=O)C(C)Cc2ccc(Cl)cc2)CC1)C(C)C +O=C(c1n[nH]c2c1CN(CC1CC1)CC2)N1CCC(c2cccc(F)c2Cl)CC1 +O=C(Nc1ccc(F)cc1)c1c(Nc2ccccc2)[nH]c(=O)n(O)c1=O +c1ccc2oc(NC3=NCC4(CN5CCC4CC5)N3)nc2c1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccc(C)cc2[nH]1)C(F)(F)F +CN1CCN(CCNc2nc3cc(Cl)c(C#CCCO)cc3nc2NCCN2CCN(C)CC2)CC1 +COc1cc(C2c3cc4c(cc3C(CCN3CCCC3CO)C3COC(=O)C23)OCO4)cc(OC)c1O +Nc1ccc(S(=O)(=O)Nc2cccc(S(N)(=O)=O)c2)cc1 +O=C(NC1CC1)c1ccc(N2CCC(Cc3ccccc3)CC2)nc1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=S)NCC +CS(=O)(=O)N1CCCC(c2csc(-c3cc(N4CCOCC4)ccc3NC(=O)c3ncc[nH]3)n2)C1 +COc1ccc2c(ccn2S(=O)(=O)c2cccc(C(=O)Nc3ccc(Cl)cc3C(=O)O)c2)c1 +CC(C)NC(=O)c1ccc(-c2nc(-c3nnc(Cc4ccc(F)cc4)o3)c(O)c3ncccc23)cc1 +Cc1ccsc1-c1c2c(nn1C)CCc1cnc(Nc3cnn(C)c3)nc1-2 +CC(C(=O)Nc1ccccc1)(C(=O)Nc1ccccc1)c1ccc(C(=O)Nc2ccccc2N)cc1 +c1cc(COc2ccc(C3=NCCN3)cc2)ccc1COc1ccc(C2=NCCN2)cc1 +CC(=O)Nc1nc2ccc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(C(F)(F)F)cc4)c3)cc2s1 +CCC(Nc1c(Nc2cccc(C(=O)NC(C)C)c2O)c(=O)c1=O)c1ccccc1 +O=S(=O)(c1ccccc1)c1cn(C2CCCNC2)c2ccccc12 +CN(CC(CCN1CCC(CCCc2ccccc2)CC1)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 +CCN(C(=O)c1ccc2c(c1)nc(NC(=O)c1ccccc1)n2CCC(N)=O)C1CCCCC1 +CCc1nc(N)nc(N)c1-c1ccc2c(c1)N(CCC(=O)OC)CCC2 +Fc1cc(OC2CC3CCC(C2)N3)cc(-c2ccccc2)c1 +O=C(NC1CCN(CCc2cccc(F)c2)C1)C12CC3CC(CC(C3)C1)C2 +CN(C)CCC(Oc1ccc(C(F)(F)F)cc1)c1ccccc1 +CCOc1ccc2[nH]c3c(NCCN(C)C)ncnc3c2c1 +O=C(CN1CCCC(c2ccccc2)(c2ccccc2)C1=O)N1CCN(Cc2cccc(C(F)(F)F)c2)CC1 +Cc1ccc(C(C)N2CCC3(CCC(=O)CC3)OC2=O)cc1 +NNC(=O)CSc1nnc(Cc2csc(NCCC(=O)O)n2)n1NC(=O)c1ccc(Cl)cc1 +CCC(C)NNC(=O)c1cc(C23CC4CC(CC(C4)C2)C3)c2ccccc2n1 +CCc1cccc(CC)c1NC(=O)NCC1(c2ccccc2)CCCCC1 +C=Cc1ccc(-c2cnccc2C2SCC(=O)N2CC(C)C)cc1 +Nc1ncc(NC(=O)c2c(Cl)ccc3c(Nc4cccc(C(F)(F)F)c4)noc23)cn1 +Cc1ccc(-n2cnc3cc(C(=O)N4CCCCC4)ccc32)cc1 +Nc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccc(N)cc4)s3)s2)cc1 +O=C(O)CNC(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +Cc1cc(CN2CCCC2CN(C)c2nc(N)n3nc(-c4ccco4)nc3n2)no1 +O=C(CCC(NS(=O)(=O)c1ccc(-c2ccccc2)cc1)C(=O)O)NCCc1ccccc1 +CN1CCN(CCCN(C(=O)Nc2ccc(F)c(Cl)c2)C2CCC3(c4cccc(NS(C)(=O)=O)c4)CC23)CC1 +CC1(O)CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)C1 +CC(NC(=O)C(O)C(O)C(=O)N1CCCC1c1csc(N(C)C)n1)c1ccc(-n2cccn2)cc1 +CC12CCC3c4ccc(OS(N)(=O)=O)cc4CCC3C1CC(=O)N(CCCCBr)C2=O +CON=C(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OC(C)C)cc2n1Cc1ccccn1 +CCOc1cc(CNC2CCCC2)cc(Cl)c1OCc1ccccc1F +Cc1c(P(=S)(c2ccccc2)c2ccccc2)n2ccccc2[n+]1CCCCc1ccccc1 +CNC(=O)Cc1ccc(Cl)c(F)c1-n1c(C2CCCCC2)nc(-c2nnc(N)o2)c1-c1ccc(F)c(Cl)c1 +O=c1c2ccccc2nc(-c2ccccc2O)n1CCc1cccc(Cl)c1 +CCNC(=O)c1ccc(C(C2=CN(O)C=CC2)=C2CC3CCC(C2)N3Cc2ccoc2)cc1 +COCCN1CCN(c2ncc(-c3cccc(C(C)Nc4cc(-c5ccc6occ(C)c6c5)nc(C)n4)c3)cn2)CC1 +O=c1[nH]c(-c2ccc(Cl)cc2Cl)nc2c1oc1ccc(Br)cc12 +Cc1cccc(N2CCN(Cc3ccc4oc(=O)ccc4c3)CC2)c1 +COc1ccc(C(O)=C(C#N)C(=NC2CCCCN(CC(=O)N3CCCC3)C2=O)Nc2ccc3oc(C)cc3c2)cc1 +CC(=O)N1CCN(C(=O)c2cc(Sc3cnc(NC(=O)c4ccc(N(C)C)cc4)s3)ccc2Cl)CC1 +CN1CCCc2ccc(Nc3nc(N4CCCCC4)nc4c3CCN(c3ncccc3C(F)(F)F)CC4)cc21 +CN(CCCN1C(=O)C2Cc3ccccc3CN2C1=O)Cc1ccccc1 +CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc(Nc3ccc(Cl)cc3)n2)c1 +CC(C)n1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(NC6CCC(O)CC6)c5)nccc34)cn2)cn1 +CN(CCCNC(=O)c1cccc2cc3cc(Br)ccc3nc12)CCCNC(=O)c1cccc2cc3cc(Br)ccc3nc12 +Nc1noc2ccc(-c3cc(Cl)ccc3Oc3cc(F)c(S(=O)(=O)Nc4ncns4)cc3F)cc12 +CC(C)(O)c1cnn2c(-c3ccc(F)c(-c4ncccc4C#N)c3)cnc2n1 +CCCCCCCCCCCCCCC1CC(O)(P(C)(=O)O)CCN1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)NCc2ccccc2)c1 +CCCOC(Cc1ccc(NC(=O)CCCCC2CCSS2)cc1)C(=O)O +COc1cccc(CNCCCNc2ccnc3cc(CCC(C)C)ccc23)c1O +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NC(C(F)(F)F)C(F)(F)F)c12 +COc1ccc(S(=O)(=O)N(Cc2cccnc2)c2c(C)cc(-c3ccccc3)cc2C(=O)NO)cc1 +Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CCC(OCC(C)(F)F)CC1 +CCCS(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)c1ccc(C(C)NS(C)(=O)=O)cc1 +CC(NC(=O)C(F)F)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 +NCc1ccc(NC(CP(=O)(O)C(N)CCc2ccccc2)C(=O)O)cc1 +CCOC(=O)N1CC2CCC(C1)C2NCCNC(=O)c1cccc(OC)c1 +NC(=O)N1CCCc2cc(-c3cncc(COCC(=O)N4CCC5(CC4)CC5)c3)cnc21 +CCc1cc(-c2c(-c3ccc(F)cc3)nc(C(C)C)n2C=CC(O)CC(O)CC(=O)O)cc(CC)c1F +CCN1C(=O)c2nc(-c3ccc(F)cc3)n(Cc3cc(F)cc(F)c3)c2N2CC(C(C)C)N=C12 +Cc1[nH]nc2c1C(c1ccc(Cl)cc1)N(c1ccc(=O)n(C)c1)C2=O +COc1ccc2c3c(c4cc(OC)c(O)cc4c2c1)CC1CCCN1C3 +COC1CCC2(CC1)Cc1ccc(Br)cc1C21N=C(N)N(C)C1=O +COc1ccc(-c2cccn3nc(Nc4ccc(N5CCOCC5)cc4)nc23)cn1 +O=C(NC1CCC(CCN2CCN(c3cccc(Cl)c3)CC2)CC1)C1CCCCC1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]nc(C#N)c1Cl +O=C(NS(=O)(=O)N1CC(F)C1)c1cc(Cl)c(OC2CC3CC3C2)cc1F +COc1cc(-c2cnc(N)c(-c3cc(OC)c(OC)c(OC)c3)c2)ccc1O +CC(C)(O)CCc1c(O)cc(O)c2c1OC(c1cc3c(cc1O)OC(C)(C)C=C3)CC2=O +CC(C)=CCN1CCn2c(=O)[nH]c3ccc(Cl)c(c32)C1C +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2noc(C(F)F)n2)CC1c1ccccc1F +O=C(Nc1cn(CC(=O)N2CCC(N3CCCC3)CC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +O=c1c2c(nc3ccccn32)n(Cc2ccccc2)c(=O)n1CC1CCCCC1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCC(N4CCCC4)CC3)cc2c1=O +CCN(CC)C(=O)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(OS(C)(=O)=O)c(=O)n1C +CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1 +Cc1ccc(C=Nn2c(S)nnc2-c2cccc(Cl)c2)o1 +CC1(C)C2CC=C(COc3ccc4c5c(c(=O)oc4c3)CCC5)C1C2 +CN1CCC(N2CCN(C(=O)CN(C)C(=O)c3nc4ccccc4n3Cc3ccccc3)CC2)CC1 +Cn1c(-c2ccccn2)c(C2CCCCC2)c2ccc(C(=O)NC3(C(=O)Nc4ccc(C(=O)O)cc4)CCC3)cc21 +O=C(c1ccsc1)c1nc(C(F)(F)F)nc2ccsc12 +CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(NCCCO)nc2s1 +O=C(NS(=O)(=O)c1ccc2ccoc2c1)c1ccc(Cl)cc1Cl +Cc1c(Cc2cccnc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O +COC1CCC2(CC1)Cc1ccc(OC(C)C)cc1C21N=C(N)N(C)C1=O +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1=O)NCc1ccccc1-c1ncc[nH]1 +Cn1cnc(-c2ccc3[nH]nc(Cc4ccc(-c5cnn(C)c5)cc4)c3c2)c1 +Cc1ncc(C)n2nc(CCc3ccc4cc(C#N)c(Cl)cc4n3)nc12 +CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(CNC3COC3)n1CCO2 +CC(C)(C)C(=O)NC(C(=O)NO)c1ccc(-c2ccccc2F)cc1 +COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)(F)C(F)F)ccc3[nH]2)c1C +CC(O)CN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCC1 +Cc1ccc(NC(=O)c2nc(C(F)(F)F)[nH]c2-c2ccc(F)c(Cl)c2)cc1Nc1ccc2ncn(C)c(=O)c2c1 +Nc1nc2c(c(=O)[nH]1)CC(CCc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)CN2 +CC12C=CC(=O)C=C1C=C(Cc1ccccc1)C1C2CCC2(C)C(=O)CCC12 +C=CC(=O)Nc1cccc(N2C(=O)N(C)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4C)nc32)c1 +COCCN(CCOC)c1nc(C)nc2c1n(C)c(=O)n2-c1c(C)cc(C)cc1C +Fc1ccc2c(C3=CCN(CCOc4cccc5c4OCCO5)CC3)c[nH]c2c1 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+COc1ncc(-c2nc3c(n2C2CCC2)C(c2ccc(C#N)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1 +Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4CCC(C(=O)NC(C)(C)C)C4)cc3)nn3cccc23)n[nH]1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(F)c(O)c2)c1 +CN1C=C(c2ccc3ccccc3n2)C(c2c[nH]c3ccccc23)c2ccccc21 +CC(C)CCN(CCC(C)C)C(=O)c1ccc2nc(Nc3cccc4[nH]ccc34)n(CCCN3CCCCC3)c2c1 +O=C(O)c1cc(-c2ccc(C3CCNCC3)cc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1 +c1ccc(CN2CCC(CCNc3ccc(-c4ccc5ccccc5c4)nn3)CC2)cc1 +CCc1cc2c(SCC(=O)N(CC)c3c(N)n(Cc4ccccc4)c(=O)[nH]c3=O)ncnc2s1 +N#CCN(CC(=O)N1CCCC(c2ccccc2)C1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +NC(=O)c1c(N2CCCC2)nc2sc3ccccc3n2c1=O +CN(C)C(=O)n1nnc(-c2ccc(Oc3cccc(Cl)c3)cc2)n1 +CC(C)(CC(O)(Cc1cc2cc(S(C)(=O)=O)ncc2[nH]1)C(F)(F)F)c1ccc(Cl)cc1C(N)=O +O=C(Nc1ccccc1)N1CC(Oc2ccc(-c3ccccc3)cc2)C1 +O=C(Nc1cccc(OC(=O)c2ccccc2)c1)NC12CC3CC(CC(C3)C1)C2 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2cnccc2OC)s1 +COc1ccc(N(C(=O)Nc2ccc3nc(-c4cc(-c5cnn(C6CCNCC6)c5)cnc4N)oc3c2)c2ccccc2)cc1 +OC1CCC(Nc2cc(-c3cccc(NC4CCOCC4)n3)c(Cl)cn2)CC1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CCCCc5ccccc54)ncc23)ccn1 +CC(=O)NC(C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1)CO +CCC(=O)Nc1cc(Cl)c(Oc2ccc(O)c(-c3ccc(C(N)=O)cc3)c2)c(Cl)c1 +Cc1noc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)n1 +NC1CCCN(c2cncc(-c3cc4c(-c5ccccc5F)n[nH]c4cn3)c2)C1 +CCOC(=O)c1ccc(Nc2cc(C3CCCNC3)nc3c(-c4cnn(C)c4)cnn23)cc1 +CC(c1ccc(N(C)C(=O)c2ccc(F)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +Cc1ccc(NC(=O)c2cc(C(C)(C)C)nn2C)cc1Nc1nc2ccccc2n1-c1cc(N)ncn1 +CC(C)(NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)Nc1nc(-c2ccc(F)cc2)c(Oc2ccc(F)cc2)s1 +O=C(Nc1ccc(CO)cc1)Nc1ccc(-c2nc(N3CCOCC3)c3ncccc3n2)cc1 +COc1cc(-c2cc(Cl)cnc2OC)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3cccnn3)ccc21 +CC=CCN1C2CCC1CC(N(c1ccc(C(=O)N(CC)CC)cc1)c1cccc(OC)c1)C2 +O=C(CC(CCCC1CCCCC1)c1nc(CNC2CCC2)no1)NO +CC1CCCN1CCc1ccc(-c2ccc(S(=O)(=O)CC3CCOCC3)cc2)cc1 +Cn1cc(Cn2cc(-c3ccc(Cl)c(OC(F)F)c3)cn2)cn1 +CC1CCC2C(C)(C)C3CC12CCC3(C)OC(=O)C(C)(C)c1cccnc1 +COc1cc(C(=O)NC2CCCN(Cc3ccc4c(c3)OCO4)C2)cc(OC)c1C +COc1cc(-c2n[nH]c3cc(NC(=O)NC(C)c4ccc(F)cc4)ncc23)ccn1 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+c1ccc2c(c1)CC(N1CCN(c3cccc4c3OCCO4)CC1)C2 +O=C(O)CN1C(=O)C(=Cc2cc3ccccc3cc2Br)SC1=S +CCCN(CCN1CCN(c2ccc(-c3ccc(OC)cc3)cc2)CC1)C1CCc2nc(N)sc2C1 +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCN2CCCC2)CC1 +Cc1oc2c(O)c3c(c(O)c2c1C(=O)NC1CCNCC1)C(=O)c1ccccc1C3=O +CC1CN(CC2(C(N)=O)CCC2)CCN1S(=O)(=O)c1ccc(C(C)(O)C(F)(F)F)cc1 +CN(c1cc(C=CC2CC2)cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CC2)c1)S(C)(=O)=O +c1cn(-c2ccc(NC3CCCN(Cc4ccc5c(c4)OCO5)C3)cc2)cn1 +Cc1ccc(ON2C(=O)C(NC(=O)OCCCCC3CCCCC3)C2C)cc1 +NC(=O)c1c(NC(=O)Cn2nc(C(F)(F)F)c3cnccc32)sc2c1CCCC2 +CN(C)CCCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 +COc1ccc2c(c1)CN(C(=O)CCN1CCCCC1)CCS2 +Nc1nc(-c2ccccc2)c2c(n1)-c1cc(Cc3cccnc3)ccc1C2=O +OC1(c2ccc3c(c2)OCO3)CCC(N2CCN(Cc3cccc(Br)c3)CC2)CC1 +c1ccc(C2CN3CCCC3c3[nH]c4ccccc4c32)cc1 +COc1ccc2nc(C)c3c(C)nc(-c4ccccc4Cl)n3c2n1 +c1ccc2[nH]c(-c3ccc(OCCCCCOc4ccc(-c5nc6ccccc6[nH]5)cc4)cc3)nc2c1 +Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ccc(-c3cncnc3)cc1)C(=O)N2c1cc(O)ncn1 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4COCc4ccc(C(C)(C)C)cc4)C(C2)N(CC2CC2)CCC315 +COc1c(C(=O)NCCN2CCCC2)sc2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3cccc(N(C)C)c3)nc12 +CNc1ccc(C=Cc2ccc(OCC(CO)CO)cc2)cc1 +Cc1cncc(-c2cc3c(cn2)cnn3-c2cccc(C3=CCNCC3)n2)n1 +CC(C)Cc1ncccc1COc1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl +CCCCc1nc2c(C)cc(-c3ccccn3)cc2n1Cc1ccc2c(ccn2-c2ccccc2C(=O)O)c1 +CN(C)Cc1nccn1-c1ccc(N2CCC(NS(=O)(=O)C=Cc3ccc(Cl)s3)C2=O)c(F)c1 +COc1cccc(Oc2cccc3c2c(C=CC(=O)NS(=O)(=O)c2ccc(F)c(F)c2)cn3C)c1 +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)N(C)C(C)C)c12 +COc1ccc(NCc2ccc(C(=O)Nc3ccccc3N)cc2)cc1 +CC(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CC(C)(C)C)NC(=O)N1CCOCC1 +CC(=O)OC1(C(C)(C)C)CCN2CC(c3ccc(Cl)cc3)CCC2C1 +Cc1cc(O)ccc1NC(=O)c1cc(N(C)C2CCCCC2)ncn1 +Cn1c(Cc2nc3cc(F)ccc3[nH]2)nc(N2CCOCC2)cc1=O +Cc1cc(COc2ccc(N3CCC(N)(CC(=O)NO)C3=O)cc2)c2ccccc2n1 +CN(C)C(=O)Cn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CCC(CC)C(=O)Nc1ccc(C(=O)NC2(C(=O)NCC#N)CCCCC2)cc1F +O=c1[nH]cnc2c1ncn2CCN(CCP(=O)(O)O)CCP(=O)(O)O +CCc1ncnc(-c2cnc3ccccc3c2)c1C#Cc1ccc(N)nc1 +CC(C)(C)c1cccc2ncn(CC(=O)CC3NCCCC3O)c(=O)c12 +O=C(Cc1cc(Cl)cc(Cl)c1)NC1N=C(c2ccccc2)c2ccccc2N(CC(F)(F)F)C1=O +c1ccc(-c2n[nH]cc2-c2ccnc(-c3ccc(CNC4CCCOC4)cc3)c2)nc1 +C=CC(OCC)C(NC(C)=O)C1NC(C(=O)O)CC1C=CC +N=c1ccc(-c2ccc(Cl)cc2)nn1Cc1cc(O)no1 +CC(C)C(N)C(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 +O=C(NN=Cc1ccc([N+](=O)[O-])o1)C1CC1 +O=C(NCc1ccc(C(F)(F)F)cc1Cl)C1COc2ncccc21 +CN1CCN(c2ccc(-c3cc4c(Cl)cc(C(N)=O)nc4n3C)cc2)CC1 +O=C(c1ccccc1)c1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1 +Cc1nc(NCCNC(=O)C2CC2)nc2ccc(NC(=O)C=Cc3ccc(OC(F)(F)F)cc3)cc12 +CCOC(=O)c1[nH]c2ccc(Cl)cc2c1Sc1cc(OC)c(OC)c(OC)c1 +O=C(O)c1cccc2[nH]c(-c3c(F)c(F)c(-c4ccccc4)c(F)c3F)nc12 +CC(c1ccc(C(=O)NCCC(=O)O)cc1)N1C(=O)C(c2cc(Cl)ccc2F)=NC12CCC(C(C)(C)C)CC2 +CC(C)(C)OC(=O)n1c(-c2ccc3c(c2)CC(NS(=O)(=O)c2ccccc2)C3)cc2ccccc21 +CCOc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Sc2ccccc2OC)CC1 +OC1(c2cccc(COc3ccc4c(-c5ccoc5)cncc4c3)n2)CC2COC(C1)O2 +CNC(=O)C1CCN(C(=O)CCC(=O)N(CC(C)(C)C)c2ccc(Cl)cc2C(O)c2ccccc2Cl)CC1 +O=C(Nc1ccc2cc(C(=O)NO)sc2c1)c1ccc2ccccc2c1 +NCCCCCCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +CC(NCC(=O)N1CCN(C(C#N)c2cccnc2)CC1)c1ccccc1 +O=C(NCCN1CCCC1)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 +NCC(CC(=O)O)c1ccc(Cl)c(OCc2cc[n+]([O-])cc2)c1 +CC(=O)OCC1=C(C)CC(C(C)C2CCC3C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC23C)OC1=O +Cc1cc(NC(=O)Nc2cc(C(C)(F)F)ccc2F)ccc1Oc1ccnc(NC(=O)C2CC2)c1 +COc1ccc(-n2nc3c(NS(C)(=O)=O)nc4ccccc4n3c2=O)cc1 +CN(C)c1ccc(Cc2cccc(-c3c(O)c4ccc(Cl)cc4[nH]c3=O)c2)cc1 +O=S(=O)(c1ccc(Cl)cc1)N(Cc1ccc(N2CCCCC2)cc1)c1ccccc1 +CCOc1c(Br)cc(C)cc1CNCCCNc1cc(O)c2ccccc2n1 +NC(=O)N1CC2CC(C1)CN(C(=O)CN1CCCC(NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C1=O)C2 +Cc1cc(NCCN(C)C)cc(C)c1-c1cnnc(NCc2nc3cc(O)ccc3s2)n1 +N#Cc1ccc(-c2ccc(S(=O)(=O)Nc3ccc4ccccc4n3)cc2)cc1 +O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ncco3)ccc1-2 +CCSC(=S)SCC(=O)c1cccc(C(=O)Nc2ccccc2)c1 +COc1cccc(F)c1CNC(=O)Nc1cc2[nH]nc(-c3ccnc(C)c3)c2cn1 +O=C(NC1CC2c3[nH]c4ccccc4c3CC(C(=O)NC(Cc3ccccc3)C(=O)O)N2C1=O)OCc1ccccc1 +CN1CCC(N2CC3CCN(S(=O)(=O)c4ccc(Cl)cc4)CC3Oc3c(NC(=O)C4CC4)cccc3C2=O)CC1 +CCCNCC(O)COc1ccc(OCc2ccccc2)cc1C(=O)CCc1ccccc1 +Nc1nc(COc2cccc(F)c2)nc2c1nnn2CC1CCCO1 +O=C(c1cc(O)c(O)c([N+](=O)[O-])c1)c1ccccc1F +CCn1c(=O)n(Cc2ccc(C(=O)Nc3ccccc3N)cc2)c(=O)c2ccccc21 +CCn1c(=O)c2c(nc3n2CCCN3CCc2ccc(OCCN3CCOCC3)cc2)n(CC)c1=O +COc1ccc(-c2nc3c(=O)[nH]c(C)nc3s2)cc1 +CC1(COc2cccc(-c3ccc(F)nc3F)n2)CCn2cc([N+](=O)[O-])nc2O1 +COC(=O)c1cccc(-c2cnc(C(=O)CCc3ccc(COc4ccccc4)cc3)o2)n1 +O=C(Nc1ccc(F)cc1F)C1C(=O)N2c3ccccc3Oc3cccc1c32 +N#Cc1cc(C#Cc2ccccn2)ccc1-c1ccc(F)cc1 +CCOC(=O)C(C#N)=CC=C1C=CN(CC(=O)N2c3ccccc3Sc3ccccc32)C=C1 +Cc1cc(-c2nnn(CC3CCC(C(=O)O)CC3)n2)cc(C(=O)NCc2cccc(F)c2)n1 +COc1ccc(C(O)=CC(=O)C(=O)O)cc1Cc1ccccc1 +NC1CCN(c2nc(-c3ccncc3)cnc2N2CCCC2)CC1 +NC(=O)c1ccc(F)c2c1CC(N(CCCCn1ccc3c(F)cccc31)C1CCC1)CO2 +COc1ccc(Br)cc1S(=O)(=O)N1CCN(C(=O)Cn2c(=O)oc3ccc(Cl)cc32)C(CN2CCCC2)C1 +O=C1NC(=S)NC(=O)C1=Cc1ccc(-c2ccc3c(c2)COC3=O)s1 +CCOC(=O)C1=CCCCC1S(=O)(=O)Cc1ccccc1Cl +O=C1OC2(CCC(C(=O)Nc3cc(-c4ccccc4)on3)CC2)c2cccnc21 +COc1c(N(C)C(=O)CNC(=O)C=Cc2ccc(C(F)(F)F)cc2)ccc(Cl)c1COc1cccc2ccc(C)nc12 +O=C(CN1C(=O)NC(CCCNC2=NCCN2)C1=O)NCC(NC(=O)OCc1ccccc1)C(=O)O +Cc1nc(-c2ccc(F)cc2Cl)c2c(N3CCc4nc(C5CC5)ncc4C3)ncnn12 +Cc1ccc(C(=O)ON=Cc2c(N3CCOCC3)n(C)c3ccccc23)cc1 +CC(C)C(=O)Nc1nc2ccc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)cc2[nH]1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC2CCN(C(=O)C3CCCN3)CC2)c2ccccc12 +O=C(NC1CCCNC1)c1ccc(O)c2[nH]c(C3CC3)nc12 +NC1=NCC(Cc2ccc(OC(F)(F)F)cc2)C(N)=N1 +Oc1n[nH]c(CN2CCOC3(CCC(c4ccccc4)CO3)C2c2ccccc2)n1 +COCCN(C(S)=Nc1c(C)cc(C)cc1C)C(C)c1cccnc1 +O=C(NO)C1(S(=O)(=O)c2ccc(OCCCc3nnnn3-c3ccc(OC(F)(F)F)cc3)cc2)CCOCC1 +CC(C)Oc1cccc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)c1 +CS(=O)(=O)c1ccc(C=C(c2ccccc2)c2ccc(F)c(F)c2)cc1 +COc1ccc(OCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 +C=C(CCCCC)c1c(C)[nH]c2cc(OC)c(Cl)cc2c1=O +c1ccc2c(c1)Cc1cc(OC3CN4CCC3CC4)ccc1-2 +CCOc1ccc(N2CCN(c3noc(C4(NC(C)=O)CCC4)n3)C(C)C2)c(C)c1 +CNC(=O)C12CC1C(n1cnc3c(NC4CC4c4ccccc4)nc(Cl)nc31)C(O)C2O +O=c1cc(-c2[nH]c(-c3ccc(-c4cn(CCO)nn4)cc3)nc2-c2ccc(F)cc2)cc[nH]1 +O=C(C=Cc1cccc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)c1)NO +CC(NC(=O)Nc1cc2[nH]nc(C3CC3)c2cn1)c1ccc(Cl)cc1 +CC1(C)CC(CCNc2ccc(Cl)cc2)(c2ccccc2)CCO1 +Cc1ccc(NC(=O)c2cccc(-n3cc(NC(=O)Nc4ccccc4F)cn3)c2)cn1 +c1ccc(CN2CCC(CCc3nsc4ccccc34)CC2)cc1 +O=C(O)C(c1ccccc1)N1CCCC(CN2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)C1 +O=C1CCCC(=O)C1C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-] +COc1cccc2c(CNC3(c4nc(-c5ccc(C)cc5)c[nH]4)CCCC3)c[nH]c12 +CC(NC(=O)Nc1cc2[nH]nc(-c3ccn4ncnc4c3)c2cn1)c1ccccc1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CN2)c1C +O=C(Oc1ccc2[nH]c(C(=O)c3cc4ccccc4[nH]3)cc2c1)c1ccc2ccccc2n1 +CCOc1cc(NC(=O)C2(NC(=O)c3ccc4c5c(n(C)c4c3)CCCC53CCCCC3)CCC2)ccc1C=CC(=O)O +CC(CCc1ccc(C2=CCCCC2)cc1)(C(=O)NO)S(C)(=O)=O +Oc1ccc2c3c1OC1c4[nH]c5ccc(C=Cc6ccccn6)cc5c4CC4(O)C(C2)N(CC2CC2)CCC314 +Cc1ccc(Cl)cc1N=C1C=C(NS(=O)(=O)c2cccs2)c2ccccc2C1=O +C=CCC(NC(=O)NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)C(=O)O +CN(Cc1ccc2c(c1)[nH]c(=NC(=O)c1ccc(-c3cn[nH]c3)s1)n2CC(C)(C)O)c1ccccc1 +CN1CC(n2cnc3ccc(-c4cccc(OCC(O)CN5CCc6ccccc6C5)c4)cc32)C1 +O=C(O)CC1CCC2(CC1)CCN(c1cc(F)cc(Cl)c1F)CC2 +O=C1OC2(CCC(CNc3ccc(-c4ccccc4F)nn3)CC2)CN1c1cccnn1 +CCC=CC(CC)CC1(CC)C=C(CC)C(=CC(=O)OC)O1 +CC1CN(c2sc(CN(C)C)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21 +CCOc1cc(=O)n(C)cc1-c1cc(N(Cc2ccccc2Cl)S(=O)(=O)Cc2ccccc2)ccc1Oc1ccc(F)cc1F +COc1cc(OC)cc(C(=O)NCC(=O)NC(C)c2ccccc2)c1 +CN(C)CCCn1c(NC(=O)c2ccc3cc4n(c3c2)CC2(CC2)CNC4=O)nc2ccccc21 +O=C1SCCc2nc(-c3ccc(C(F)(F)F)cc3)[nH]c(=O)c21 +NC(=S)Nc1cccc(OCCCCCN2CCN(c3ccc(Cl)cc3)C2=S)c1 +O=C(O)CC(Cc1cc(OCCc2ccc3c(n2)NCCC3)no1)c1cnc(-c2ccc(Cl)cc2)s1 +Cc1oc(-c2ccccc2)nc1COc1ccc(Cc2ccc(OC(C)C(=O)O)cc2)cc1 +CC1(N2CCC(N(c3ccccc3)c3cccnc3)CC2)CCN(C(=O)c2cccc3ccccc23)CC1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(=O)Cc3ccc(F)cc3)c2)[nH]1 +C=CCCC12CC1(C(=O)OCC)C(=O)Nc1ccc(Br)cc12 +Cc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccccc2[N+](=O)[O-])c(C)c1 +CCS(=O)(=O)c1ccc2[nH]c(-c3cccc(-c4ccccc4)c3C)nc2c1 +CCCN(C)c1nccc(N2CCC(Oc3ccc(C(C)C(=O)NCC)cc3)C2)n1 +N#Cc1c(-c2ccc(C(F)(F)F)cc2)cc(NCCN2CCCC2)n2c1nc1ccccc12 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(F)cc1Oc1ccc2cc(C#N)ccc2c1Br +CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cc(F)c(F)c(F)c1F +COc1ccccc1N1CCN(CCN2C(=O)NC3c4ccccc4N(C)C3C2=O)CC1 +CC(C)C(C)(c1ccc(-c2cnc(N)nc2)cc1)c1noc(N2CCC(O)CC2)n1 +CCN1CCN(c2cc(C)c3cc(NC(=O)CCC(=O)Nc4ccc(F)c(Cl)c4)ccc3n2)CC1 +CCC(COCC1CC1)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(=NOCC(C)(C)O)C5)cn3)n2)s1 +CC(C)CC(NC(=O)Cc1ccc2ccccc2c1)C(=O)NC1CC(=O)OC1O +O=C(Cc1cc2ccccc2cn1)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1 +N#CN=C(NCCCc1ccccc1)NCCCc1c[nH]cn1 +COc1cccc2c1[nH]c1c3ccncc3cc(C(N)=O)c21 +COc1cc(-c2ccc(NC(C)c3ccc(F)cc3)nc2)ccc1-n1cnc(C)c1 +Cn1nc(-c2ccncc2)cc1NC(=O)C(Cc1ccccc1)NCC(=O)O +CN1C(=O)C=CC2(C)C3CCC4(C)C(O)CCC4C3CCC12 +CCCn1c(=O)c2c(nc3[nH]c(C)cn32)n(Cc2cccnc2)c1=O +O=C(c1cccc(F)c1F)N1CCc2nc(COc3cccc(F)c3)oc2C1 +NC(=O)c1ccc(-c2nc(-c3ccccn3)c(-c3ccc4c(c3)OCO4)[nH]2)cc1 +COc1cc(OC)cc(N2CCN(C(=O)Nc3nc4cc(C)ccc4nc3OC)CC2)c1 +COc1cc(=O)oc2cc(OCCCN3CCN(c4ncccn4)CC3)ccc12 +C[Si](C)(C)C#Cc1cn(C2OC(CO)C(O)C2O)c(=O)[nH]c1=O +COc1cc2c(cc1O)C(C)N(Cc1cccc(O)c1OC)CC2 +CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nc2ccccc2n1-c1ccccc1N(C)C +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)NCCC(=O)O)cc12 +COc1ccc(Cn2c(C(Cc3ccccc3)NC(C)=O)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)CO)cc1 +CC(C)C(CO)NCc1nc(-c2ccc(F)c(Cl)c2)ccc1F +O=C(Nc1ccc(Cl)cc1)C1CN(C(=O)c2cccc(-c3cccnc3)c2)CC(F)(F)C1 +Cc1ccc(-c2nn(-c3ccccc3)cc2-c2nc3ccccc3[nH]2)cc1 +COc1cc(OC)cc(N(CCN2CCCC(N)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CCC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)(Oc1ccccc1)C(=O)O +COC(=O)C(C)CNP(=O)(Oc1ccccc1)OC1CC(n2cnc3c(N)ncnc32)CO1 +Cc1nc2c(OC(F)F)cccc2n1-c1ccc(C(=O)NC2CC2)s1 +CCC1CN(c2nc(N)c(C(=O)NCCS(C)(=O)=O)nc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +CC(C)(Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1)C(=O)O +CCCCCCCCn1cc(CN)c2cc(-c3cccc(C)c3)ccc21 +O=C(CCCCCCC(=O)NCc1ccc2ccccc2n1)NO +O=C1NN(c2ccc(I)cc2)C(=O)C1=Cc1cc2c(cc1Br)OCO2 +Cc1ccc(C)c(NS(=O)(=O)c2cc(C(=O)Nc3ccccc3-c3ccccc3)ccc2Cl)c1 +Oc1nc2c(c3nc(-c4ccccc4F)nn13)CCCCC2 +CCCc1nn2ccc(C(=O)NC(CC)c3ccccc3)cc2c1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(F)c(C)n3)C2)cc1 +COCOc1cc(OC)ccc1C(=O)CCC(=O)NC(Cc1ccccc1)C(=O)C(N)=O +O=C(CC1SC(c2ccc(Cl)cc2Cl)N(CC(=O)NCCCN2CCOCC2)C1=O)NCc1csc2ccccc12 +CCN(CC)C(=O)c1ncc(C2=CC3(CCNCC3)Oc3ccccc32)cn1 +O=c1cc(Cn2ccnc2)c2ccc(Oc3ccc(Cl)cc3)cc2o1 +c1ccc(Nc2nc3ccccc3c3[nH]c(C4CCCC4)nc23)cc1 +Cc1cc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5ccc(CN)cc5)nc34)CC2)no1 +CC1CN(C(C)CO)C(=O)c2cc(NC(=O)C3CCCCC3)ccc2OC1CN(C)S(=O)(=O)c1ccccc1Cl +CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1Oc1ccccc1C(=O)O +COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1N1CC(C)NC(C)C1 +Brc1ccc(Cn2ccc3nc(C=Cc4ccccc4)nc-3c2)cc1 +CN(C)C1CCN(c2ccc(N3Cc4cn(-c5ccc(Cl)cc5)nc4C3=O)cn2)C1 +O=C(Nc1cc(Cl)ccc1C1CCCCC1)c1cnn2cccnc12 +CCCN(CC1CC1)C(=O)c1c(CC)nc2n(-c3c(C)cc(C)cc3C)c3ccc(F)cc3n12 +COc1cc(Oc2ccccc2)ccc1-c1nc(C2CCC2)n2ccnc(N)c12 +O=C(Nc1ccc(NC(=O)N2Cc3ccncc3C2)cc1)c1cncs1 +N#Cc1ccc(Oc2cccnc2)c(Oc2cccc(Cl)c2)c1 +CC12CCC(O)CC1CCC1CC3(C)C(CCC34CO4)CC12 +CN1CCN(Cc2cn(S(=O)(=O)c3ccc(F)cc3)c3ccccc23)CC1 +Oc1cccc(-c2nc(N3CCOCC3)c3[nH]cc(C4CCN(Cc5ccc(F)cc5)CC4)c3n2)c1 +CC1CN(c2nnc(-c3ccc(C(F)(F)F)cc3)c3ccccc23)CCN1C(=O)c1ccccc1 +CCCCCCCCC(C)(C)c1cc(=O)c2cc(OS(N)(=O)=O)ccc2o1 +CCNC(=O)Nc1nc2cc(-c3ccn(CCOC)c(=O)c3)c(OC3CCOC3)nc2s1 +COc1cc2c(cc1N1CC(C)NC(C)C1)N(S(=O)(=O)c1ccc3ccccc3c1)CC2 +CC1(NC(=O)CBr)CCC(C(C)(C)NCC(O)COc2cccc3[nH]ccc23)CC1 +C#CCn1c(-c2ccco2)nc2c(N)nc(C#CC3(O)CCCCC3)nc21 +CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CCCC(C)(C)C2)cc1 +CC(C(c1ccc2cc(OCC(C)(C)C)ccc2c1)n1ccnc1)N(C)C +Cc1c(F)ccc(C(=O)Nc2cc(-c3ccc(F)cc3)ccc2N2CCN(C)CC2)c1Cl +COc1cc(C(=O)NCc2ccc(F)cc2Cl)ccc1-c1cn[nH]c1 +Cc1cccc(CN2CCC3(CC2)CCN(C(=O)c2ccccc2)CC3)c1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(N2CCOCC2)cc1F +COc1cc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc(OC)c1 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+O=C(Nc1ccncc1)Nc1ccc(-c2nc(N3CCOCC3)c3ccn(CC(F)(F)F)c3n2)cc1 +CN1CCN(c2ccc(Nc3nc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)cc2)CC1 +Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1cnc(N)cn1 +O=[N+]([O-])c1cccc2c(NCCCCCCCCNc3c4c(nc5ccccc35)CCCC4)c3c(nc12)CCCC3 +Cn1c(SCCCN2CCOC(c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccncc1 +CC1=CCC2C(C1)c1c(O)cc(C(C)(C)c3cccc(Cl)c3)cc1OC2(C)C +Cc1ccccc1N1CC(C(=O)Nc2cccc(C(F)(F)F)c2)CC1=O +CCCOCCn1c(=O)c(N2CC3CC2CN3)nc2cnc(-c3ccc(OC)nc3)cc21 +CC(C)NC(=O)c1cc(-c2ccccc2)nc2c1cnn2Cc1ccncc1 +O=C(NCCCCN1CCCCC1)Nc1ccc(-c2ccccn2)nc1 +COc1ccc(S(=O)(=O)N2CCCc3cc(-c4cccnc4)ccc32)cc1 +CCCS(=O)(=O)NC1CC(N(C)c2ncnc3[nH]ccc23)C1 +CC(C)CCN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O +CCNc1nnc(-c2ccc(C#CC3(CN4Cc5ccc(OC)cc5C4=O)NC(=O)NC3=O)cc2)o1 +CC(C)c1ncc(COCCCCc2nnn[nH]2)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CNc1nc(Nc2cc(F)c(N3CCCCC3=O)cc2OC)ncc1C(F)(F)F +CCOC1(c2ccccc2)Sc2ccccc2-n2c1noc2=O +CCC(C(=O)NCCCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1)(c1ccccc1)c1ccccc1 +Nc1scc(CN2CCN(c3ccc(C(F)(F)F)cc3)CC2)c1C(=O)c1ccc(Cl)cc1 +CCCCCCCCCCCCNC(=O)Oc1cccc(-c2csnn2)c1 +CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)C=Cc1ccccc1 +CCN(CC)C(=O)CN(c1cc(Cl)ccc1N(C)C)S(=O)(=O)c1ccc(OC)c(OC)c1 +Cc1c(C(=O)N2CCc3ccccc3C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1-c1ccccc1 +CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(F)cc12 +CCN(c1cc(-c2ccc(CNCCO)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1 +CN(C)CCOc1ccc(Nc2cc(-n3cnc4cccnc43)ncn2)nc1 +COc1ccc2ccc(OC)c(CCNC(=O)C3CC3)c2c1 +Cc1c(C)c2c(c(C)c1N)CC(C)(CSc1ccc(O)cc1)O2 +CC(c1ccccc1)N1CCN(c2c(Cl)cnc3[nH]c(-c4ccc(N(C)C)cc4)nc23)CC1 +CS(=O)(=O)Nc1ccc(-c2cncc3ccccc23)c(OC(F)(F)F)c1 +COc1cccc(C(C)NC(=O)c2ccc(-c3c(C)n[nH]c3C)cc2OC)c1 +CON=C(CCN1CCN(c2ccccn2)CC1)c1ccccc1C +CC(O)c1cnc(N2CCn3c(nc4ccc(S(C)(=O)=O)cc43)C2C(C)C)nc1C(F)(F)F +OCCCOc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +CCC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)CCC1O +C=CCN(C(=O)OCc1ccc([N+](=O)[O-])cc1)C1CCN(CCC(Cn2cncn2)c2ccccc2)CC1 +CC(C)NCC(O)COc1ccc(CCOCC2CCCC2)cc1 +NC(CC(CC=Cc1ccc([N+](=O)[O-])cc1)C(=O)O)C(=O)O +CCCCNC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)Cc1ccc2ccccc2c1)C(C)CC +C=CC(=O)Nc1ccc2c(c1)CC(=O)Nc1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn1-2 +Cc1nc2sccn2c(=O)c1CCN1CCN(C2CC(c3ccc(F)cc3)c3cc(Cl)ccc32)CC1 +COc1ccc(-c2cc3c(c(=O)o2)CC2(O)C(C)(CCC4(O)C(C)(C)C=CC(=O)C42C)O3)cc1 +Cc1nnc2n1-c1sc(C#CCn3c(=O)ccc4ccccc43)cc1C(c1ccccc1Cl)=NC2 +COc1ccc(OCC(C)(O)C(=O)N2CCc3c(C#N)cccc32)cc1 +CC(C(=O)NC1COC1)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 +CC(C)c1ccc(SCC(=O)N2CCOCC2C(=O)OCCCc2cccnc2)cc1 +CCCn1c(=O)c2c(nc3[nH]c(C)c(C)n32)n(Cc2ccccc2)c1=O +CC(=O)N(c1ccccc1)C1CC(C)N(C(=O)c2cccc(C)c2)c2ccccc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(N2CCC(F)(F)CC2)CC1 +O=C(NC1CCN(Cc2ccc(OC3CCNCC3)c(Br)c2)CC1)c1cc2ccc(-c3ccc(F)cc3)cc2s1 +CCC(=O)Nc1cc2c(NCc3ccccc3)ncnc2cc1OC +CC1C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C2C(OCc2ccccc2)C1 +COc1ccc2ncc(F)c(C(O)CCC3CCN(C4CC(c5ccc(F)s5)C4)CC3C(=O)O)c2c1 +COc1cccc(-c2cn(C3CCN(CC(N)=O)CC3)c3ncnc(N)c23)c1 +Cc1cc(N2CCN(c3ccnc4cc(Cl)ccc34)CC2)nc(Nc2ccccc2)n1 +Cc1noc(C)c1-c1cnc(N)c(-c2ccc(C(=O)NC(CO)c3ccccc3)c(F)c2)n1 +ON=C(CCN1CCN(c2ccccn2)CC1)c1ccc(Cl)cc1 +COc1ccc(S(=O)(=O)N2CCOC(Cn3ccnc3)C2)cc1 +CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCN(C2CCN(C(=O)OC3CCCC3)CC2)CC1 +O=S(=O)(NCC1CCCC1C(O)CCc1ccccc1)c1ccc(OC(F)(F)F)cc1 +CC(C)(Cc1ccc(O)cc1)NCC(O)c1ccc(O)c2c1OCC(=O)N2 +CSCCN1CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +COc1ccc(NC(=O)c2ccc(F)c(Nc3ncnc4cnc(N(C)CCN5CCCC5)nc34)c2)cc1C(F)(F)F +OC1CCN(CCOc2ccc(Oc3nc4ccccc4o3)cc2)CC1 +O=c1n(CCc2ccc3ccccc3n2)nc2cccc(-c3ccncc3)n12 +CCCCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)OCC +COc1ccc(NC(=O)Nc2nc3cn(CCc4ccccc4)cc3c3nc(-c4ccco4)nn23)cc1 +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(CSc2ccncc2)cc1 +Cc1cc(C(=O)NCc2cc(Cl)ccc2-n2cnnn2)cc(N(C2CCCC2)S(C)(=O)=O)c1 +N=C(N)c1ccc(-c2ncc(-c3ccc(C(=N)N)nc3)s2)nc1 +c1ccc2c(CCCCN3C4CCC3c3c([nH]c5ccccc35)C4)c[nH]c2c1 +O=C(c1cc(F)ccc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncon2)c1 +COc1ccccc1-c1ccc2[nH]c(C=CC3CCCCC3)nc2c1 +O=C(c1ncc[nH]1)N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +c1cc(-c2cc3c(cn2)[nH]c2ncc(-c4ccc(CN5CCCCC5)cc4)cc23)cnn1 +COCCc1nc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Nc2ccccc2)N2C1=NC1CCCC12 +COc1cc(C)c(Cc2nc(-c3ccc(-n4cnc(C)c4)c(OC)n3)n[nH]2)cc1C(C)C +COc1c(C)cc(Nc2nccc(-n3cc(C)c(CN4CC(O)C4)c3)n2)cc1C +CN(C)CCN1C(=O)c2cccc3c2c(cc2nc(-c4ccccc4)sc23)C1=O +CN1CCN(c2cccc(C(=O)Nc3n[nH]c4cc(OCCOCc5ccccc5)ccc34)c2)CC1 +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3cnn(-c4ccccc4)c3C(F)(F)F)c3ccccc32)CC1 +COc1ccccc1N1CCN(CCN(C(=O)C23CCC(CF)(CC2)CC3)c2ccccn2)CC1 +O=C(O)c1cc2c(Br)c(Oc3ccc(O)c(C(=O)c4ccc(F)cc4)c3)c(Br)cc2o1 +CC1C(O)C2(C)C(=O)C=CC3=CC(=O)C1(O)CC32C +COCCCN1CCN(C(=O)N2Cc3c(NC(=O)c4ccc(F)cc4F)n[nH]c3C2(C)C)C(C)C1 +CS(=N)(=O)CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 +CCc1cn(-c2nc(C(=O)O)cs2)c2cc(Cl)ccc12 +CC(C)CCN(C(=O)Nc1ccc(OC(F)(F)F)cc1)C1Cc2ccc(SC(C)(C)C(=O)O)cc2C1 +Cc1cnc(NC(=O)c2cc(Oc3cnc(C(=O)N(C)C)cn3)c3cn(C)nc3c2)cn1 +Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2c(F)cncc2F)s1 +O=c1c2cc(F)ccc2[se]n1CCn1[se]c2ccc(F)cc2c1=O +NC(CC(=O)N1CCCC1CNC(=O)c1ccc(F)cc1)Cc1ccccc1F +NCC(c1ccc(Cl)cc1)c1ccc(-c2cn[nH]c2)cc1 +Nc1ncnc2c1ncn2C1OC(COP(=O)(O)CP(=O)(O)OP(O)(O)=S)C(O)C1O +COC1CCC2CCc3c(ccc[n+]3CCc3ccccc3)C2C1 +CN1CCN(c2nccc(NCCCNc3ccnc4cc(Cl)ccc34)n2)CC1 +COc1ccc(B(O)O)c(NC(=O)c2ccc(Oc3ccc(C(F)(F)F)cc3)nc2)c1 +COc1ccccc1Nc1ncccc1C(=O)NCC(O)CN1CCN(c2ccccc2OC(C)C)CC1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(NC(=O)C(N)C(C)(C)C)CC1 +CC(=O)N1CCN(C(=O)c2cc(CSc3cnc(NC(=O)c4ccc[nH]4)s3)cc(C)c2C)CC1 +Cc1cnc(C)c(N2CC3CCN(C(=O)c4c(F)cccc4-n4nccn4)CC32)n1 +CC1=CC(=O)N(Nc2nc(-c3cccs3)nc3sc(C(N)=O)c(C)c23)C1=O +NC(=O)c1ccc(N2CCN(c3ccccc3Cl)CC2)c2cncnc12 +CCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 +COc1cc(C(=O)c2nc(-c3ccc(N(C)C)cc3)c[nH]2)cc(OC)c1OC +COCCc1cc(OC2CC2)c(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C(C)C)n2)cc1C +COc1ccc(C2N(c3ccnc(NC(C)c4ccc(Oc5ccccc5)cc4)n3)C(=O)OC2(C)C)cc1 +O=C(C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1)N1CCC(O)C1 +NC(=O)C1(NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)CCOCC1 +Cn1c(=O)c2c(c(C#N)c(N3CCCC(N)C3)n2Cc2ccccc2)n(C)c1=O +NS(=O)(=O)NCCCCC(NC(=O)Cc1ccccc1)C(=O)Nc1nc(-c2ccccc2)cs1 +CCCC(CC(=O)O)n1ccc2cc(OCCc3ccc4c(n3)NCCC4)ccc21 +O=c1ccc2c(OCCCCOc3ccc4ccccc4c3)c3ccoc3cc2o1 +Cc1ncc(Cn2nc(I)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)s1 +N=C(Nc1ccc2c(c1)Cc1cc(NC(=N)c3ccccn3)ccc1-2)c1ccccn1 +C=CCOC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +CC(O)CNc1nc(NCc2cccnc2)c2ncn(C(C)C)c2n1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(Cl)cc3)nn21 +Cc1cccc(-c2nsc(N3CCN(C(=O)Nc4ccccc4)CC3)n2)c1 +CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(C#Cc4cnc5[nH]c(C)cc5c4)c3)cc2C(F)(F)F)CC1 +COc1cc(-c2cc(C3CCCNC3)n3ncnc(N)c23)cc(F)c1CO +COCCn1nc(N)c2c(-c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)cccc21 +CC(C)N1C(=O)C(C)(C)c2cc(-c3ccc(C#N)n3C)cc(F)c21 +O=C(OCC#CCSc1nnc(-c2cccc3ccccc23)o1)c1sc(Cl)c(Cl)c1Cl +CN(C)C1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NC3CCCC3)CC2)c(C)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(N=CN(C)C)cccc3nc2-1 +Cc1cc(OCCCNCC2CCCN(C)C2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 +FC(F)(F)Oc1ccc(OC2CC2)c(CNC2CCC3NC2(c2ccccc2)CC3c2nnn[nH]2)c1 +C=Cc1ccc(-c2cccc(CNc3nc(C#N)nc4c3ncn4CCCO)c2)cc1 +COc1ccc(COCCOc2ccc3c(NC(=O)c4ccc(N5CCN(C)CC5)cc4)n[nH]c3c2)cc1 +CN(CCCc1ccc(Cl)cc1Cl)c1nc(NCCc2ccc(O)cc2)nc(N2CCNCC2)n1 +Cn1nc(C(F)F)cc1C(=O)Nc1ccc(F)c(C2(C(F)F)N=C(N)OC3CC32)c1 +CN(C)C(=O)CCCCCCCCNC(=O)C(C)(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C +N=C(N)NCCCCNc1ccnc2c1ccc1c(NCCCCNC(=N)N)ccnc12 +CCN(c1cccc2ccccc12)C1CCCc2nc(-c3c(C)cc(OC)cc3C)cc(OC)c21 +Cc1cc(F)ccc1S(=O)(=O)N1CCCC(Cn2ccnc2)C1 +N=C(N)c1ccc(-c2cccc(-c3ccc(C(=N)N)cn3)c2)nc1 +O=C(O)C(=O)CC(=O)c1cccn1Cc1ccc(F)cc1 +CC(C(=O)NCc1cc(Br)cc2nc(O)c(O)nc12)c1ccccc1 +O=C1C(=CC=Cc2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccccc1 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+CCc1ncnc(-c2ccc(C(=O)N3CCN(C4CCOCC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1C +CC(C)n1c(=O)ccc2cnc(Nc3ccc(N4CCNCC4)cc3)nc21 +Nc1nc(NCCCCc2ccccc2)nc2c1ncn2C1OC(CO)C(O)C1O +O=S1(=O)N=C(NC2CCCCC2)OC2(COC2)C12CC2 +Brc1c(Br)c(Br)c2[nH]c(NC3CCNCC3)nc2c1Br +COc1c(Br)cc2nc(O)c(O)nc2c1[N+](=O)[O-] +COc1cc(OC)c(-c2c3cc(O)c(=O)cc-3oc3cc(O)c(O)cc23)cc1OC +CC(C)(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccco3)cc1)C2=O +CC(=O)Nc1ccccc1-c1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1 +COc1cccc2c1nc(N)n1nc(CN3CCN(c4cnn(C)c4)CC3C)nc21 +COC(=O)CSCCCCCC=C(NC(=O)C1CC1(C)C)C(=O)O +CCOc1ccccc1N1CCN(CCCNC(=NC#N)c2ccncc2)CC1 +O=[N+]([O-])c1ccc(-[n+]2c(-c3ccccc3)cc(-c3ccccc3)cc2-c2ccccc2)cc1 +CCC(CC)Nc1nc(C)nc(N(CC)c2ccc(C(C)C)cc2Br)n1 +CN1CCCCCCCCCCCC(=O)OCC2C(CC3CCC2N3C)c2ccc1cc2 +CS(=O)(=O)c1ccc(C(O)C(CO)NC(=O)C(Cl)Cl)cc1 +O=C(Nc1cccnc1)c1ccc(OC(F)F)c(OCC2CC2)c1 +[O-]c1ccccc1-[n+]1c(-c2ccccc2)cc(-c2ccccc2)cc1-c1ccccc1 +O=c1[nH]c(-c2cccc(=O)n2CC2CNCCOC2c2ccc(Cl)c(F)c2)no1 +CCCn1c(=O)[nH]c2[nH]c(-c3ccc(S(=O)(=O)NCCc4ccccc4)cc3)nc2c1=O +CCC(C)C(NC(=O)CC(C)C)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 +O=C(c1ccccc1)N1CCC(CNCc2cccc(-n3cccn3)n2)CC1 +Cc1cc(S(=O)(=O)NC(=N)NNc2ccc(S(N)(=O)=O)cc2)c(SCc2ccccc2)cc1Cl +O=C1Nc2cc(Cl)c(Cl)cc2C1=C1Nc2ccccc2C1=NO +CCCCCCCCCCCCCCCCCC(=O)OCOC(=O)c1cn2c3c(c(N4CCN(C)CC4)c(F)cc3c1=O)OCC2C +Cc1cccc(-c2nc3ccccc3c(C(=O)NC(C)c3ccccc3)c2CN2CCC(N3CCCCC3)CC2)c1 +CC(C)(C)NC(=O)c1ccc2nc3[nH]c4ccccc4c3nc2c1 +CCNc1nc(Nc2cc(OC)c(C(=O)N3CCOCC3)cc2Cl)ncc1C(F)(F)F +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)co1 +O=C(CN1CCCC1)Nc1ccc(C(c2ccc(F)cc2)(c2ccc(NC(=O)CN3CCCC3)cc2)C(F)(F)F)cc1 +Nc1ncc(-c2cc(N3CC(N4CCCC4=O)C3)nc(N3CCC(F)(F)C3)n2)cc1OC(F)F +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC(C)(Cc1ccccc1)C(=O)NCCCCCCCCO +N#Cc1cnc2ccc(NCc3cccnc3)cc2c1Nc1ccc(F)c(Cl)c1 +CCOc1ccc(Cc2cc(C3SC(CO)C(O)C(O)C3O)c(OC)cc2OC)cc1 +O=C1CCc2ccc(OCCCCNCCc3cn(Cc4ccccc4)c4ccccc34)cc2N1 +COc1ccc(C2(c3ccc(F)c(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc1C +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(N3CCN(C4CC4)CC3)nc12 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+O=C(NC(Cc1ccc2oc(CCNc3ccccn3)cc2c1)C(=O)O)c1c(Cl)cccc1Cl +FC(F)(F)c1ccc(Nc2nc(-c3ccncc3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CN(CCc1ccc2cc(-c3ccc(C#N)cc3)ccc2c1)C(C)(C)C +CC(C)CCOc1ccc2c(c1)C1OCCCC1C(C1CCCCC1)N2 +O=C(O)CC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)CC1CCC1 +C=C1CCC2C(C)(C(=O)OC)CCCC2(C)C1CCC1=CCc2c(O)ccc(O)c2C1 +COc1cccc(Cn2c(CCCc3c[nH]c4ccccc34)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)c1 +CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3ccc(C(=O)O)s3)cc12 +Cc1ccc(NC(=S)OC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 +CC(C)(C)c1ccc(CN(Cc2cccs2)n2ccnc2)cc1 +O=C(C(Nc1ccccc1F)c1cc2ccccc2s1)N1CCCC1c1ccccn1 +CC(C)(Cc1ccc(F)cc1)NCC(=O)N1CCCC1C(=O)c1ncon1 +COC(=O)c1ccn2ncc(C=NN(C)S(=O)(=O)c3cc([N+](=O)[O-])ccc3C)c2c1 +COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(C(=O)c1ccc[nH]c1=O)CC2 +CNC(=O)C(Cc1ccc(NC(=N)N)cc1)NC(=O)C(CC(C)C)C(CCCc1ccccc1)C(=O)NO +O=C1C(=Cc2ccc(O)c(O)c2)C(c2ccc(O)c(O)c2)Oc2ccccc21 +O=c1[nH]c2c(-c3ccc(Cl)cc3)c[nH]c2c(=O)n1CCN1CCN(c2ccccc2Cl)CC1 +Cc1cc(-n2cccn2)c2cccc(OCc3c(Cl)cncc3Cl)c2n1 +CCCN1C(=O)C(C2=CC(=O)c3[nH]cc(CCN)c3C2=O)N(C)C1=O +CCCn1c(=O)c2nc(-c3ccc(OCc4nc(-c5ccc(C)cc5)no4)cc3)[nH]c2n(CCC)c1=O +O=C1C(=Cc2ccc(Cl)cc2)CN(C(=O)c2ccc(OCCN3CCCCC3)cc2)CC1=Cc1ccc(Cl)cc1 +COc1ccncc1-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc21 +O=C(O)C(CCC(=O)N1c2ccccc2CC1C(=O)O)CCc1ccccc1 +Cc1nc(-c2ccccc2)c(C(=O)N2CCN(c3ccc(Cl)c(Cl)c3)CC2)o1 +COc1ccc(C2NC(C(=O)O)Cc3c2[nH]c2ccccc32)cc1CN1CCN(c2ccccc2F)CC1 +C=C(NC(c1ccc(Cl)c(F)c1)C1(F)CCNC1)c1ccc2cnc(Nc3ccnn3C)nc2c1 +Cc1ccc(C(N)=O)cc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12 +COc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNC4)CC3)ccc12 +CCCC(=O)N1CCN(c2nc(Cc3ccccc3)c3c(c2C#N)CC(C)(C)OC3)CC1 +COCc1ccc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)cc1 +COc1cc(CCNCCc2ccc(O)c3[nH]c(=O)ccc23)ccc1OCCCc1ccccc1 +Nc1noc2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(F)c(Cl)c5)CC4)cc3)c12 +COc1cc(C(=O)O)ccc1C=C1CCN(C(=O)C(C2CCCCC2)C2CCCCC2)CC1 +COc1c(Cl)cc(C2=C(c3ccc(S(N)(=O)=O)cc3)CCC2)cc1Cl +CC(=O)Nc1ncc(Cc2csc(CCO)c2C)c(N)n1 +COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCCC3)C2=O)CC1 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+O=S(=O)(c1ccccc1-c1ccc(CNC2c3ccccc3CC2O)cc1)N1CCCCC1 +CSc1ncc(C2C(C(=O)OCCc3ccccc3)=C(C)NC(C)=C2C(=O)OCCc2ccccc2)n1Nc1ccccc1 +O=[N+]([O-])c1cc(F)ccc1S(=O)(=O)Nc1cccc2cccnc12 +Cc1cccc(C(=O)N2CC(C)OCC2Cc2cc(-c3ncccn3)ccc2F)c1-n1nccn1 +CCc1[nH]c(=O)c(N(C)C)c(Cc2cc(C)cc(C)c2)c1C +CC1(O)CC(c2nc(-c3ccc(SC4CCCCO4)cc3)c3c(N)nccn23)C1 +CCc1c(Cc2cc(C)cc(C)c2)nc(SCc2ccc([N+](=O)[O-])cc2)[nH]c1=O +Nc1ccc2c(c1)[nH]c1cc(C(F)(F)F)ccc12 +COC1CCC2(CC1)Cc1ccc(CC3CCCCC3)cc1C21N=C(N)N(C)O1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CC4c4ccccc4)ncc23)ccn1 +CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(CC(=O)NCc3c(C)cccc3C)c2)NC(=O)N1 +O=C1c2c(c(O)c3nccnc3c2O)C(=O)N1Cc1cc(Cl)cc(Cl)c1 +O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(Cl)cc3)cc2)cn1 +CC(C)(C)c1ccc(-c2cnc(N)cn2)c(F)c1O +N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCCCCOc3cc(C(F)(F)F)ccc3C(=O)N2)CC1 +CC(C)CC(C(=O)NC(Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)CC(C)C +CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(Cl)cn1)c1nccs1 +CCNC(=O)Nc1cn(-c2ncc(Br)cn2)c2cc(-c3ccn(C)c(=O)c3)cnc12 +O=C(C1CCCN(c2ccc3nc(-c4cc(C5CC5)ccn4)[nH]c3n2)C1)N1CCCC1 +COc1ccc2c(c1)C1(CC1c1ccc3c(C=Cc4cc(F)c(CN5CCOCC5)c(F)c4)n[nH]c3c1)C(=O)N2 +COC(=O)C1(C)CCCC2(C)c3cc(OC)ccc3CCC12 +CCCCCCS(=O)(=O)c1nc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)cc(C(=O)O)n1 +O=[N+]([O-])C=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)Nc1cccc(Oc2ccccc2)c1 +Cc1nn(C)c2ncc(C(=O)NO)c(N(C)S(=O)(=O)c3ccc(F)cc3)c12 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(C)s3)CC2)nc1 +Cc1cc(C2SCC(=O)N2CCCN(C)CCOc2ccc3c(c2)OCO3)cc(C(C)(C)C)c1O +CC(C)N1CCN(C(=O)c2ccc(C(CCN(C)C)Oc3ccc(C(F)(F)F)cc3)cc2)CC1 +CCOc1cc2c3c(c1)-c1c(ccc(O)c1O)CC3N(C)CC2 +C=CCn1c(=O)n(Cc2nc3ccccc3n2CCC(C)C)c2ccccc21 +O=c1[nH]c(N2CCC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CNc1nc(Nc2cc(OC)c(-c3cncn3C)cc2Cl)ncc1C(F)(F)F +O=C(C[n+]1cc(-c2ccc(F)cc2)n2c1CCC2)c1cccs1 +CCCN(CCC)C(=O)C(C)c1c(-c2ccc(Cl)cc2)[nH]c2ccccc12 +O=C(NCc1ccc(F)cc1)c1cn2c(c(O)c1=O)C(=O)N(CCOc1ccccc1)CC2 +O=C1NC(=O)c2c1c1ncccc1c1[nH]c3ccccc3c21 +O=C(NCc1ccc(-c2ccccc2)cc1)c1c(NCc2ccc(-c3ccccc3)cc2)[nH]c(=O)n(O)c1=O 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+Clc1ccc(-c2c(-c3ccc(Cl)cc3Cl)nc(CNC3CCCC3)n2C2CCC2)cc1 +Oc1ccc2c(c1)C13CCCCC1(O)C(C2)N(CC1CCC1)CC3 +OC1CC2CCCCC2CC1N1CCC(c2ccccc2Br)CC1 +Cc1cc(-c2nc3c(cnc4c(F)cccc43)[nH]2)on1 +CCCCCCCCCCCOC(=O)C(CCC(=O)NC(CCCC(N)C(=O)O)C(=O)O)NC(=N)N +O=S(=O)(c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cc1)N1CCCC1 +CC(C)CCc1nn(CCC(C)C)c(=O)c(C2=NS(=O)(=O)c3cc(OCC(N)=O)ccc3N2)c1O +CN(C)C(=O)n1nnc(-c2ccc(Cn3ccc4ccccc43)cc2)n1 +CCCCCN1C(=O)C(=NNC(=O)C(C)(C)C)c2ccc(OC)cc21 +Cc1cn(C2OC(COP(=O)(O)O)C(O)C2O)c(=O)[nH]c1=O +O=C1CCN(Cc2ccc3oc4cccc5c(=O)[nH]nc(c3c2)c45)CC1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(Nc3ccc(-c4ccccc4)cc3)CC2)CC1 +CC(C)(O)Cc1ccc2c(c1)c1cc(OCCCC(F)(F)F)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 +Cc1ccccc1-c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 +CCCCN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1 +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCCCC1 +COc1ccc(C)cc1NC(=O)Nc1cccc(C(=O)c2cn(C3CCCC3)c3ncnc(N)c23)c1 +CCc1cccc2c1c(C(=O)c1ccc(Cn3c(C)nc4cnccc43)cc1)cn2C(=O)N(C)C +CC1=C2CCC3C(CCC4(C)C(O)CCC34)C2(C)CCC1=O +CC(C)CC(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)CNC(=O)NC(C)(C)C +Nc1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2nc(-c3ccc(F)cc3)sc2n1 +CCCS(=O)(=O)Oc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc(C(=O)NN3CCCCC3)c2C)cc1 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4cc(F)c(C#N)c(F)c4)CC3)c2c1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(C4CCCCC4)s3)c2)C(O)C(O)C1O +Cc1nc(N)nc2c1cc(-c1cnn(CC(C)(C)O)c1)c(=O)n2C1CCCC1 +Nc1ccccc1NC(=O)CCCCCNC(=O)c1ccccc1C(=O)c1ccccc1 +COC(=O)Nc1nc2ccc(S(=O)(=O)c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 +C=S(N)(=O)C(C)(C)c1cc(N2CCOCC2C)nc(-n2c(NC)nc3ccc(F)cc32)n1 +Cc1noc(-c2cccc3c2-c2ccccc2C3(O)C(F)(F)F)n1 +Cc1ncn(-c2ccc(Cl)cc2C2=CC(=O)N(C3CCCC(C)C(=O)Nc4ccccc4-c4ccnc3c4)CC2)n1 +COc1ccc(CCNC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cc1 +COc1ccccc1N1CCN(Cc2c(C)nc3cc(C)nc(C)n23)CC1 +O=c1oc2ccccc2n1CC1CCN(Cc2ccc(-c3ccccc3)cc2)CC1 +COc1cc(OC)cc(-c2cncc(-c3ccc(N4CCNCC4)cc3)c2)c1 +Cc1ccc2c(c1)CN(CCc1ccc(C(C)C)cc1)C(=S)N2 +COc1ccc(-c2nc(CN3CCN(Cc4cccc(Cl)c4)CC3)c(C)o2)cc1 +CC(C)(C#N)c1cc(Cn2cncn2)cc(-c2ccc(OS(N)(=O)=O)cc2)c1 +CCCN(c1cc(C(=O)Nc2ccn(CC(=O)O)n2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC +NC1(c2ccc(-c3nc4ccc(-c5ccccn5)cn4c3-c3ccccc3)cc2)CCC1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3ccncc3)cc2)cc1)C(=O)O +S=c1[nH]c2ccc(OCCN3CCN(c4ccccc4)CC3)cc2[nH]1 +O=C(CCc1ccncc1)Nc1ccc(C(=O)c2ccccc2)cc1 +CCCN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +O=C(NCC(c1ccc(Cl)nc1)N1CCC(F)(F)CC1)C1COc2ncccc21 +CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(Cl)cccn12 +O=C(Nc1ccccc1N1CCCC1)c1ccc2ccccc2n1 +COc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Br)cc4)CC3)c2cc1OC +O=C(c1ccco1)N1CCN(c2cnn(CCCN3CCN(c4ccccc4Cl)CC3)c(=O)c2Cl)CC1 +CC(C)CC(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccc(Cl)cc2)cc1 +CC1CCCN1CCc1ccc(-c2ccc(S(=O)(=O)N3CCC(O)C3)cc2)cc1 +O=C(Nc1ccc(C(=O)N2CCc3c[nH]nc3-c3sccc32)cc1)c1ccc(F)cc1Cl +Cc1ccc(Oc2ccc(N(CC(NCc3cccnc3)C(=O)NO)S(C)(=O)=O)cc2)cc1 +CC(=O)N1CCCC(Nc2ncccc2-c2cnc3ccn(C)c3n2)C1 +CC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)CC1CCC(C(=O)O)CC1 +CCc1cccc(CC)c1-c1cc(OC)c2c(n1)CCCC2N(C)c1ccc(OC)c2ccccc12 +C#CCN(Cc1ccc2nc(CO)nc(O)c2c1)c1ccc(C(=O)NCc2cccc([N+](=O)[O-])c2)cc1 +CC(C)(C)OC(=O)NCc1cccc(CNC2CCN(CCc3ccccc3)CC2)c1 +O=C(NCc1nnc[nH]1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +CC1(C)Cc2nc(N3CCOc4ccc(Nc5ccc(N6CCNCC6)nn5)cc43)sc2C(=O)N1 +CC(C)c1cc(NC(=O)C2CCN(CC(=O)N3CCN(c4ccc(-c5ncccn5)cc4)CC3)C2)ccc1O +CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O +CC12CCC(O)C(C)(CO)C1CCc1cc(CO)c(O)cc12 +S=C(NCCCNCCCCNCCCNC(=S)NCC(c1ccccc1)c1ccccc1)NCC(c1ccccc1)c1ccccc1 +COc1cc(OCc2csc(C3(c4ccccc4F)CCOC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +[C-]#[N+]c1ccc(N2C(=O)C3(CCC3)N(c3ccc(CCCC(N)=O)cc3)C2=S)cc1C(F)(F)F +O=Cc1c[nH]c2c1ccc1c3ccc(Br)cc3[nH]c12 +CN(CCCOc1ccc(Oc2ccccc2)cc1)CCC(=O)O +CC(C)C1=C(Sc2ccccc2)C(COCCO)C(=O)NC1=O +CNC(=O)c1cc2c(Oc3ccc(C4(CO)CC4)cc3)cncc2s1 +CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(-c3nc(C(C)C)no3)cc2C#N)CC1 +[C-]#[N+]c1c(Oc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)nn(C)c1C(F)(F)F +CN(C)C(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C +COCC=Cc1c(Cl)c2c(Cl)cc(C(N)=O)nc2n1C1CCCNC1 +Cc1ccc(C(N)=O)cc1Nc1ncnc2c1cnn2-c1ccccc1 +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(CCc3ccncc3)CC2)cc1 +CC(C)OCCCNC(=O)CN1CCC(N(N)CC(=O)N2CSCC2C#N)CC1 +O=C(COc1ccc(Cl)cc1)Nc1nc2nn(CCCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +C=CCCC(=O)N1CC(C(C)OC(=O)CCCc2ccncc2)C1=O +Cc1ccc(NC(=O)c2cccc3c(N)nc(C)nc23)cn1 +COc1cc2c(Oc3ccc(NC(=O)c4nccc(-c5ccccc5)n4)cc3F)ccnc2cc1OCCCN1CCCC1 +N=C(Nc1ccc2c(c1)CCCN2C1CCNC1)c1cccs1 +Cc1nc2cc(OCC(O)CN3CCN(CC(=O)NC(C)c4ccc(F)cc4)CC3)ccc2s1 +Cc1cccc(C)c1-c1ccc(C(=O)NCCNC(=O)c2ccc(OC3C4CC5CC3CC(C(=O)O)(C5)C4)cc2)cc1 +COc1cc(-c2cc3ncccc3c(OCC3CNC(=O)C3)n2)cc(OC)c1OC +N#Cc1ccc(OC(F)(F)F)cc1N1CCC2(CCC(CC(=O)O)CC2)CC1 +CC1(C)CCCC(n2cnc(CC(CCCN)C(=O)O)c2)C1 +CC(C)N1CCCC(COc2ccnc3ccc(C#CCNC(=O)c4cccn(Cc5ccc(F)c(F)c5)c4=O)cc23)C1 +O=C(CCCCCN1CCN(c2cccc(C(F)(F)F)c2)CC1)c1ccccc1O +Cn1ncc2ncn(Cc3nc(CCc4ccc(Cl)cc4)no3)c(=O)c21 +Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC2(CCS(=O)(=O)CC2)c2ccc(N3CCOCC3)cc21 +NC1(c2ccc(-c3nc4cc(C5CC5)ccn4c3-c3ccccc3)cc2)CCC1 +CCc1coc2ccc(-c3cc(NC(C)c4cccc(O)c4)nc(C)n3)cc12 +CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2C2CC(CI)CCC21 +CNS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O +CCCCc1nc(SC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 +CC(C)n1nc(C(=O)NCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc21 +COc1cc2cc(NC(=O)CCCN(C)Cc3ccccc3)c(=O)oc2cc1OC +CC(C)(CCCC=C(c1ccccc1)c1cccnc1)C(=O)O +Cc1cc(OCC2Oc3ccccc3O2)ccc1C(=O)n1c(C)c(CC(=O)O)c2ccccc21 +COc1c(F)cccc1Oc1ccc(C(F)(F)F)cc1C(=O)Nc1ccc(C(=O)O)nc1 +COc1ccc2c(c1)C(=O)c1ccc(-c3nnc(C)o3)cc1S2(=O)=O +Cc1c(Cl)cccc1S(=O)(=O)NC(C)(C)CC(=O)NC1CCCCCC1 +CN1CCC(OC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1 +CN(Cc1ccccc1)C(=O)C(Cc1ccccc1F)NC(=O)C1CC(O)CN1C(=O)c1cn(C)c2ccccc12 +C=CCN1C2CCC1C(C(=O)OC)C(c1ccc(SCC)cc1)C2 +COc1ccc2c(c1)C(=O)C(c1ccc(Oc3ccccc3)cc1)=[N+]2[O-] +CC1CN(CCC(=O)NC2CCCCC2)C2Cc3ccc(O)cc3C1(C)C2 +O=C(CSc1nc2ccccc2c(=O)n1C1CC1)Nc1cc(C(F)(F)F)ccc1Cl 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+O=S(=O)(c1ccc(Nc2nc(SCc3ccccc3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1)C(F)(F)F +COC(=O)c1cccc(-c2cnc(C(=O)CCc3ccc(OC4CCN(C(=O)OC(C)(C)C)CC4)cc3)o2)n1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5Cl)CC4)cc3)cc2n(C)c1=O +CS(=O)(=O)Nc1ccc2ccc3ncc(-c4cnsc4)cc3c(=O)c2c1 +CCC(CC)CNC(=O)c1ccc2c(C)cn(Cc3ccc(C(=O)NS(=O)(=O)c4ccccc4Cl)cc3OC)c2c1 +CN(C)CCCOc1cnc(-c2cccc(Cn3nc(-c4cccc(F)c4)ccc3=O)c2)nc1 +CC1(O)CN(Cc2ccc(Nc3nccc(-c4cnc(N5CCC(F)C5)c(C#N)c4)n3)cn2)C1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(ncn2-c2ccccn2)C1 +COC(=O)c1sccc1NC(=O)Cc1cccc2cnccc12 +CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CNCC2CCCCC2)cc1 +CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(C(=O)NC(CC(=O)O)C(=O)O)n1C +CCCCc1nc2cc(C=CC(=O)NO)ccn2c1CN(CCC)CCCC +CCN1C(C(=O)NCc2cccc(C(F)(F)F)c2Cl)CCS1(=O)=O +O=C(NCCCN1CCOCC1)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COc1ccc(C(=O)NO)cc1NC(C)c1ccc(Cl)cc1 +COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cn1cc(C(C)=O)c2ccc(NC(=O)OC3CCCC3)cc21 +CN1C(=O)N(c2cncnc2)CC1C(=O)NCc1cccc(C(F)(F)F)c1Cl 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+c1ccc(-c2noc(C34CC5CC(CC(C5)C3)C4)n2)nc1 +O=C1NC2(CCCC2)C(=O)NC(Cc2ccccc2)C(=O)NCC=Cc2ccccc2OCCNC1Cc1cscn1 +CC1(C=Cc2cncs2)C(C(=O)O)N2C(=O)CC2S1(=O)=O +CC(c1nc2c(c(=O)[nH]1)C1CCCN1C(=S)N2c1ccccc1)N1CCOCC1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3[S+](C)[O-])c(=O)n(CC(N)c3ccccc3)c2=O)c1F +C=Cc1ccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 +Cc1ccc(C2OC(CO)C(O)C(O)C2O)cc1Cc1ccc(-c2ncccn2)s1 +CSCCc1c(-c2cccnc2)nn(-c2ccc(Cl)c(Cl)c2)c1OCCCC(=O)NC(Cc1ccccc1)C(N)=O +COc1cccc(Br)c1C(=O)NC(Cc1ccc(-c2cn(C)c(=O)n(C)c2=O)c(C)c1)C(=O)O +Cc1nc(-c2cn3c(n2)-c2cc(C(C)N4CCN(C(C)(C)C)CC4)ncc2OCC3)n(C(C)C)n1 +CC(C)c1ccccc1SC1=C(O)OC(c2ccccc2)(c2ccccc2)CC1=O +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N(C)C)nc2c1 +CCc1cc2c(c(OCC(F)(F)F)c(C(=O)NC3CCN(C(=O)CO)CC3)n2C)c(=O)n1CC(=O)c1ccccc1 +O=C(NCc1ccccn1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +COC(=O)c1[nH]c2ccc(Br)cc2c1Cc1cc(O)c(OC)c(OC)c1 +COc1cc(OCc2cccc(-c3ccc4nncn4c3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Cc1cnc(F)c(-c2nc(C(=O)Nc3cnn(C)c3N3CCCC(N)CC3)c(N)s2)c1 +COc1ccccc1-c1cc(NC(=O)c2cccc(NS(C)(=O)=O)c2)ncn1 +CCCCNC(=O)c1cc2ccc(O)cc2oc1=Nc1ccc(OC)cc1 +CCc1ccc(-c2nc3ccc(NCc4cccc(C(F)(F)F)c4)cc3n(CCNC(C)=O)c2=O)cc1 +COc1ccc(S(=O)(=O)n2ccc3c(CN4CCN(C)CC4)cccc32)cc1 +CCN1CCC(F)(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CC1 +CCCN(CCC)c1cc(C)nc2c(-c3ncc(N(CC)CC)cc3C)c(C)nn12 +NC1CC(N2CCn3c(nnc3C(F)(F)F)C2)COC1c1cc(F)ccc1F +NC(=O)c1nc(-c2ccccc2)cc2c1[nH]c1cc(C(=O)N3CCOCC3)ccc12 +O=C(c1ccccc1)c1cccc(C=c2[nH]c(=O)c(=Cc3ccccn3)[nH]c2=O)c1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)n1)c1ccc(F)cc1 +O=S(=O)(c1cccs1)c1nnn2c1nc(NCc1cccs1)c1sccc12 +O=C(c1cccc(F)c1-n1nccn1)N1CCOCC1Cc1cccc(-n2nccn2)c1 +NC(CO)(CCc1ccc(-c2cn(Cc3ccc(Cl)cc3)nn2)cc1)COP(=O)(O)O +Cc1cnc(-c2ccc(C3C(c4ccccc4)C3(Cl)C(=O)NO)cc2)nc1 +[C-]#[N+]c1scc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)cn4)CC3CO2)c1C +O=C(O)Cc1ccc(-n2nc(C3CCCC3)cc2NC(=O)Nc2nc(CCOCc3ccccc3)cs2)cc1 +CN1C2COCC1CC(OC(=O)c1cn(-c3cnn(C)c3)c3ccccc13)C2 +CCC(CC)Nc1cc(C)nc(Oc2c(C)cc(Br)cc2C)c1C +CC(C)(C)C(=O)Oc1ccc(C(=O)c2ccccc2)cc1CCC(=O)O +CN(C)c1ccc(-c2nnc(Nc3ncc(C(=O)NO)cn3)o2)cc1 +CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCCCC2)c1O +COc1cc(Nc2ncc(-c3nc(-c4ccccc4)cs3)c(NC3CC(CO)C(O)C3O)n2)ccn1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1c[nH]c2c(-c3ccccc3)cccc2c1=O +O=C(Nc1cc(Oc2ccncc2)cc(Oc2ccc(F)cc2)c1)N1CCC(O)(c2ccc(F)cc2)CC1 +CN(C)C1(CNCCC2CCCCCC2)COc2ccccc2OC1 +NC(CC(=O)N1CCNc2ccccc2C1)C1CCc2cc(F)c(F)cc21 +Cc1ccc(CN2C(=O)C(C(C#N)C(=O)O)c3ccccc32)cc1 +O=C1NC(=S)SC1=Cc1cc(Br)ccc1OCc1ccccc1Br +Cc1ccc(C=C(Oc2ccc(C=NNc3ccnc4cc(Cl)ccc34)cc2)C(=O)c2ccc(Cl)cc2)cc1 +COc1ccc(S(=O)(=O)N(CCn2cc(COCCOCCOCCOCCOCCF)nn2)C(C(=O)NO)C(C)C)cc1 +O=C(O)CCC(CC=Cc1cccnc1)CCCCNS(=O)(=O)c1ccc(Cl)cc1 +CCCCCn1c(C)c(C(=O)c2cccc3cccc(I)c23)c2ccccc21 +O=C(NC(Cc1ccc(OCCNc2nc3ccccc3[nH]2)cc1)C(=O)O)c1c(Cl)cccc1Cl +CC(C)Cc1ccc(OCC(=O)N(Cc2nc(-c3cccnc3)no2)C(C)C)cc1 +CCC(=O)N(Cc1ccccc1-c1ccccc1)C1CCNC1 +C=C(Br)C(=O)Nc1cccc(-c2cn3c(-c4ccc(OC)cc4)csc3n2)c1 +CC1(C)CC(=O)c2c(oc3c(Br)cc(NS(=O)(=O)c4ccccc4)cc23)C1 +c1cc2[nH]cc(CCCN3CCOCC3)c2cc1-n1cnnc1 +Cc1nccnc1C(C)N1CCc2c(ccc(COc3ccccc3-c3cccc(N4CCC5(C(=O)O)CC5C4)n3)c2C)C1 +CC(C)c1c(OCC(O)CN2CCCCC2)ccc2c1CCC1C(C)(C)CCCC21C +Cc1ccc2nc(C)c3nnc(-c4cc(OC5CCOC5)ccc4Cl)n3c2n1 +O=C(Nc1ccc(I)cc1)c1ccc(CN2CCOCC2)cc1 +CC(C)Oc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +COc1ccc2nc(C)c3c(C)nc(-c4cccn4C)n3c2n1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccncc2[nH]1)C1CCC1 +N#Cc1c(-c2cccs2)cc(-c2cc3c(ccc4ccccc43)oc2=O)[nH]c1=O +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCN5CCCC5)c[nH]4)c3)cc2)c1 +COc1cc(C=C2C(=O)NC(=O)C2=Cc2ccccc2)cc(OC)c1OC +CC1(COc2ccc(Cl)cn2)CN(C(=O)N2CCN(S(C)(=O)=O)CC2)CC1c1ccc(Cl)cc1 +CN(C)CCOc1cc(N2CC3CNCC(C3)C2)cc(F)c1F +Cn1cc(F)cc(C2CCCN2c2ccn3ncc(C(=O)NC4CCC4)c3n2)c1=O +Fc1ccc(C23CCC4CCCCC4(OO2)C(OCc2ccccc2)O3)cc1 +COc1cc2c(cc1OCc1ccccn1)-c1n[nH]c(-c3ccc(-c4ccc(O)cc4)cc3)c1C2 +CC1CC1CNc1cc(C(=O)NC(Cc2ccccc2)C(N)CCC(F)(F)F)cc(N(C)S(C)(=O)=O)n1 +CC12CCC3C(CC4CC45CC(O)CCC35C)C1CC=C2c1cccnc1 +Brc1cnc(Nc2ccc3[nH]cnc3c2)nc1Nc1ccc2[nH]cnc2c1 +CC1(Cc2ccc(Br)cc2)C(=O)N(c2cc(Cl)cc(Cl)c2)c2ncc(S(=O)(=O)N3CCC(O)CC3)n21 +O=C1NCN(C2CCCCC2)c2c1cnc1[nH]ccc21 +COc1cc(OCc2cccc(-c3ccc(C(=O)OC(C)(C)C)nc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CNC(=O)C1OC(n2cnc3c(NC4CCCC4)nc(N)nc32)C(O)C1O +COc1ccc(Nc2ncc(C(C)N3CCN(S(C)(=O)=O)CC3)cc2-c2nc(C)nc(N)n2)cn1 +CCNC(=O)N1CCN(C)C(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2C)C1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4ccc(CO)cc4)nc31)C(O)C2O +COc1cn(C(CC(C)F)C(=O)Nc2ccc(C(=O)O)cc2)c(=O)cc1-c1cc(Cl)ccc1C#N +CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CCC2CC(=O)O)cc1C#N +CCC(c1ccccc1)c1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc1-2 +O=C(O)COc1ccc(C(=O)c2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)cc1 +COc1ccc(CN(C)Cc2ccncc2)cc1-c1ccc(S(=O)(=O)NC2CCC2)s1 +COC(=O)C1=CN(Cc2ccc(OC)c(OC)c2)C=C(C(=O)OC)C1c1cccc(F)c1 +CCCN1CCC(CNCc2cn(-c3ccc(C(F)(F)F)cc3)nc2-c2ccc(C(F)(F)F)cc2)CC1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Cc2cccc(F)c2)C1 +O=C1NC(=O)c2c1c(-c1c(Cl)cccc1Cl)cc1c2c2cc(O)ccc2n1CCCC(=O)n1ccnc1 +CC(NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N1CCCC1CNC(=O)C1CCCN(C(=N)N)C1 +CN(CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1)C(=O)c1ccc2nc(N3CCCC3)oc2c1 +Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(C=CCCN4CCCCC4)ccc23)cc1Cl +CC(C)CN1C(=O)C(=Cc2ccc(N(C)C)cc2)SC1=Nc1ccccc1 +CCCCC(NC(=O)OC1CN(C(=O)Oc2ccccc2)CC1(C)C)C(=O)C(=O)NC(C)c1ccccc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cc(-c2ccc(Cl)cc2)n[nH]1 +COc1ccc(-c2nnc(-c3ccc4nc(-c5c(C)cc(CCC(=O)O)cc5C)[nH]c4c3)o2)cc1 +CC1CN(Cc2ccc(N(C)C)nc2)CC1c1nn2c(C3CCOCC3)ncc2c(=O)[nH]1 +COC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 +CCc1ncnc(-c2ccc(C(=O)N3CCC(N(C)C)C3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +CN1CCN(CCCn2cc(-c3cncc(-c4ccsc4)c3)c3ccccc32)CC1 +COc1n[nH]c2ncc(NC(=O)c3c(F)ccc(NS(=O)(=O)N4CCCC4)c3F)cc12 +CCCCNCC(=O)OC1C2(C(C)C)OC2C2OC23C2CCC4=C(COC4=O)C2CC2OC213 +CCCC(C)Nc1c2c(nn1Cc1ccc(-c3cccc(F)n3)cc1)N1C(=NC3CCCC31)N(C)C2=O +CN1C(=O)CC(c2ccccc2)C1C(O)c1cc(-c2ccccc2)cs1 +CCCCCCCCCCCn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1 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+O=C(O)C1(COc2ccc(-c3ccc(-c4ncc(C(F)(F)F)[nH]4)nc3)cn2)CCCC1 +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCN1CCC(c2ccccc2)CC1)C1CC1 +COc1ccc(Cl)cc1N1CCN(CCCN2C(=O)CC(C)(c3ccccc3)CC2=O)CC1 +CN(CC(=O)N1CCCCC1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCC1CCCO1 +Cc1c(F)cc(C(=O)NC2CC2)cc1-c1c(F)cn2c(-c3ccncc3Cl)nnc2c1F +[H]c1cc(-c2nnc(C34CCC(c5noc(C(C)(F)F)n5)(CC3)CC4)n2C)c(C(F)(F)F)cc1[H] +O=c1ccn(C2C=CC(OCP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1 +NC(=NO)N1CCC(CNC(=O)C2CCC3CN(S(=O)(=O)CCc4ccccc4)CC(=O)N32)CC1 +Cc1cccc(-c2nn(C(=S)Nc3cccc(C#N)c3)cc2-c2ccc3nc(C)nn3c2)n1 +CCc1cc2c(cc1N1CCN(CC3(O)CCNCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +Nc1nc(NCCNc2ncc(N3CCOCC3)c(-c3ccc(Cl)cc3Cl)n2)ccc1[N+](=O)[O-] +CC1(c2cc(NC(=O)c3ncc(Cl)cc3Cl)ccc2F)N=C(N)OCC1(F)F +O=C(Cc1ccccc1)NNC(=O)C(OCC=CBr)C(O)C(O)C(OCC=CBr)C(=O)NC1c2ccccc2CC1O +COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccc(F)c4)ncc(N)c3=O)nc2c1 +CNC(=O)c1nc(-c2ccc(Cl)c(S(=O)(=O)Nc3cccc(C)c3)c2)cnc1N +O=C(O)c1cccc(-c2ncccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 +Fc1ccc(CN2CCC(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +Cc1cc(N2CCN(C(=O)c3ccco3)CC2)n2ncc(-c3ccccc3)c2n1 +COC(=O)CC1(C(=O)Nc2ccc(-c3ccccc3C(=O)OC)cc2)CC(c2cccc(C(=N)N)c2)=NO1 +CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccn3)cc2)n1 +CC(Sc1cc(-c2ccc(C(=O)N3CCN(C(C)C)CC3)cc2)cnc1N)c1c(Cl)ccc(F)c1Cl +COc1ccc(CC(O)CO)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1 +CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)cc2cn(C)nc12)C(=O)C1CC1 +O=C1N(c2ccc(OC(F)(F)F)cc2)CC2CC(NS(=O)(=O)c3cccnc3Cl)CN12 +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2NC2CCCCC2)N2C1=NC1CCCC12 +Cn1c(NC(=O)c2cccc(C#N)c2)nc2cc(C(=O)N3CCCCC3)cnc21 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCn3ccc4cccc(F)c43)c2)c1 +CC(C)(C)C1COCC(COC(=O)N2CCC(CO)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 +CC1CC1c1cc(NC(=O)Nc2ccc(Cl)cc2)n(Cc2ccccc2)n1 +COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)cc(C(=O)N(C)C)c1 +CCCCNC(=O)CCC1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 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+NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1cccc(Cl)c1 +CCN(C(C)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl +CC(O)C(=O)NC(Cc1cccc(-c2nccs2)c1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +CC1CCCCN1c1ccc(N2CCN(S(=O)(=O)c3cccc(Cl)c3)CC2)nn1 +O=C(c1ccc(Oc2ncccc2C2CCCOC2)cc1)c1nc2ccccc2[nH]1 +N#Cc1cccc(-c2ccc3c(c2)CCN(CC(=O)Nc2cc(Cl)cc(Cl)c2)C32CCN(C3CCC3)CC2)c1 +Cc1ccc(NC(=O)N2CCc3nc(N4CCCC4)nc(OC(C)C)c3C2)cn1 +Cc1cc(NC(=O)C(C)(C)c2ccccc2)cc(S(=O)(=O)N2CCOCC2)c1C +CC(Cc1c[nH]c2c(OS(=O)(=O)c3cccnc3)cccc12)NCC(O)c1cccc(NS(=O)(=O)c2cccs2)c1 +CN(C)Cc1ccc(Nc2c(C#N)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)cc1 +CC(C)=CCCC(C)=CCCC(C)=CCN(C)C(=O)C(CP(=O)(O)O)C(=O)O +COc1ccc(Nc2c(-c3ccc(F)cc3)c(C)nn2-c2ccccc2C)c(C(=O)O)c1 +CN(C)c1ccc(C=Cc2sc3cc([N+](=O)[O-])ccc3[n+]2C)cc1 +CN1CC=C(c2c[nH]c3ccc(N4C(=O)c5ccccc5C4=O)cc23)CC1 +COc1cc2c(cc1Nc1nc(Nc3ccoc3C(N)=O)c3cc[nH]c3n1)N(C(=O)CN(C)C)CCC2 +O=C(Nc1ccc(Cl)cc1)N1C2CCC1CC(S(=O)(=O)c1ccccc1)C2 +O=C(NCCCc1cn2c3c(cccc13)CCC2)C1CCC1 +Cc1cc(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C(C)C)n2)c(OC2CC2)cc1C(=O)C(C)C +CCCN(Cc1sc(Nc2c(C)cc(Cl)cc2C)nc1C(F)(F)F)CC1CC1 +COc1cccc(CCCCCc2cccc(OC)[n+]2C)[n+]1C +O=C(NC12CC3CC(CC(C3)C1)C2)c1cn(CC2CCOCC2)c2ccccc12 +C=C(C)C(O)CCC(CO)C1CCC2(C)C3CCC(C(=C)C)C4(CCC(=O)O)CC34CCC12C +CC(=O)Oc1ccc(Cl)c(-c2cc(C)c3nc(Nc4cccc(OCCN5CCCC5)c4)nnc3c2)c1 +Cn1c(Nc2c(F)cccc2Cl)nc2cc(C(=O)Nc3cc(F)cc(C(F)(F)F)c3)c3c(c21)OCCO3 +N#Cc1c(-c2cccc(C=O)c2)[nH]c2nc(N)nc(N3CCCC3)c12 +N#Cc1ccc(Nc2nccc(NCc3cccc(F)c3)n2)cc1 +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(c2ncccn2)CC1 +CN1CCCN(c2ncc3ncnc(Nc4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4F)c3n2)CC1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cn5ncc6ccc(F)cc65)C4)cc23)ccn1 +O=C(NC1CCCC1Nc1cnc(C(F)(F)F)cn1)c1ccccc1-n1cccn1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NNC(C)C)[nH]c3ccc(Cl)cc23)c1 +CCNC(=O)Nc1cc(Nc2ccccc2)c(C(=O)Nc2ccccc2)cn1 +CC1OC(=O)C2(NCC3CC3)CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4C#N)cn3)C12 +CC(C)C(=O)Nc1cccc(C2CCN(CCCNC(=O)C(c3ccccc3)c3ccccc3)CC2)c1 +CC(CO)Nc1ncc2c(n1)CN(C(=O)NC1CNCC1c1ccc(C(F)(F)F)cc1)CC2 +Nc1nccn2c(C3CCC(CNC(=O)c4ccoc4)CC3)nc(-c3cc4ccccc4[nH]3)c12 +O=C(CCCc1ccccc1)N1CCC(Cc2c[nH]cn2)CC1 +CC(C)N1CCC(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)S1(=O)=O +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CN(C(=O)C(C)(C)O)C1)CC2 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)C1CO +CCCCc1nc2ccc(N)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +c1ccc2sc(-c3cn[nH]c3NCCc3cnc[nH]3)nc2c1 +COc1cc(N)ccc1-c1ccc2c(-c3nc4c(N5CCN(C)CC5)cccc4[nH]3)n[nH]c2c1 +O=C(C(=O)N1CCN(C(=O)c2cc[nH]n2)CC1)c1c[nH]c2cccc(F)c12 +COC(C(=O)NC1CCc2ccccc2NC1=O)C(O)C(O)C(O)C=CC(C)(C)C +O=C(CCCCN1CCN(c2ccccc2)CC1)NC1c2ccccc2SCC2CCCCC21 +COc1ccccc1C(c1nnnn1Cc1ccc(F)cc1)N1CCN(C)CC1 +CCOc1cc(Cl)ccc1OC(c1ccccc1)C1CNCCO1 +Cc1ccccc1-c1cnnc(NCc2cc(-c3ccccc3)[nH]n2)n1 +COCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NCC2CCCCC2O)c1 +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCC(CCN2CCCC2)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(NC(=O)c2csc3c(N)ncnc23)c1F +COc1ccc(CN2CCC(NCCCCCCCCn3ccc4ccccc43)CC2)cc1 +O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3ccccc3F)CC2)nc1 +O=C(Nc1cccc2cccnc12)c1ccc(N2C(=O)C3C4CCC(CC4)C3C2=O)cc1 +Cn1cc(N2C(=O)c3nn(C4CC4)cc3C2c2ccc(Cl)cc2)cc(Cl)c1=O +Cc1nc2ccccc2n1Cc1ccc(CNC(=O)C(O)C(O)C(=O)N2CCCC2c2cccs2)s1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccc(C)cc2)c1 +COc1c(C(O)CN2CCN(C(=O)Cc3ccc(-n4cnnn4)nc3)CC2)ccc2c1COC2=O +O=c1n(Cc2nc3ccccc3n2CCCCF)c2cnccc2n1C1CC1 +CC(C)CC(C=O)NC(=O)C(NS(C)(=O)=O)C(C)C +O=C(Nc1cnn(S(=O)(=O)c2ccc(N3CCOCC3)cc2)c1)c1ccccn1 +CC(C)=CC(=O)Nc1sc(Nc2ccc3cc(CO)ccc3c2)nc1C(N)=O +CCOc1ccc2[nH]c3c([N+](=O)[O-])ccc4c3c(nn4CCNCCO)c2c1 +CC(C)N(Cc1cnc[nH]1)c1cccc(Oc2cccc(Cl)c2)c1 +CN1CCN(c2nc(Nc3ccccc3)c3cnn(C)c3n2)CC1 +CC1(C)OC2=C(CC1OC(=O)c1ccc(Br)cc1)C(=O)C(=O)c1ccccc12 +O=C(CNC(=O)c1ccc(Cl)cc1)OC(C(=O)Nc1ccc(Cl)cc1C(F)(F)F)c1ccccc1 +NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCc4ccccc4)nc32)CC1 +c1ccc(C2CCNC3(CCN(c4ncnc5[nH]cnc45)CC3)C2)cc1 +Cc1c(N)c(C)c2c(c1CC(C)C)OC(C)(C)C2 +CC(C)CNC1CCN(c2ccc(NC(=O)C(C)(C)c3ccccc3)cc2Cl)CC1 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+NC(=O)c1ccc(-c2cc(-c3ccc4c(c3)OCCO4)cnc2N)cc1 +CCCCc1nc2ccccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Nc1ncnc2c1c(-c1cccc(O)c1)nn2Cc1cc2cccc(Cl)c2c(=O)n1C1CC1 +CC(C)(C)CC(=O)N1CCC(CNC(=O)c2cc(Cl)ccc2C2CCN(CCN3C(=O)COc4ccccc43)CC2)CC1 +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)c(F)c2)cn1C(C)C +COC(=O)C1C(c2ccc(C)cc2)CC2CCC1N2CC=CCF +CCNC(=O)Nc1nc2cc(-c3ccc4cnnn4c3)c(=O)n(C(C)C)c2s1 +CC(CCC(=O)NCCC(=O)Nc1nnc(S(N)(=O)=O)s1)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C +CC1=CCCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CC3(COC3)C2)c1O +CN(C)CCNC(=O)c1ccc([N+](=O)[O-])c2c(O)c3cccnc3nc12 +CCOc1ccc(Cc2cc(C3OC(SC)C(O)C(O)C3O)c(OC)cc2Cl)cc1 +CCCCc1nnc(SCc2ccc3ccccc3c2)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +COc1cc2nccc(Oc3ccc4c(C(=O)NCC(F)(F)F)cccc4c3)c2cc1OC +N#Cc1nccc(N2CC(S(=O)(=O)c3ccccc3C(F)(F)F)CC2C(=O)N2CCC(F)(F)C2)n1 +CCCN1CCC(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)S1(=O)=O +NC(=O)C1CCC(c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)CC1 +COc1ccc(C2CC3CSC(N)=NC3(c3ccc(F)cc3F)CO2)cc1 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+CCN1C(=O)CCC1C(=O)NCc1ccc(F)c(C(F)(F)F)c1 +COc1cccc2c1c(=O)c1c(NCCN(C)C)ccc3c(CNCCN(C)C)nn2c31 +O=C(Nc1nc(-c2ccccc2)ns1)c1ccc(O)cc1 +COc1cc(CNC(=O)C2(Cc3ccccc3)OC(=O)N(C3CCc4ccccc43)C2=O)cc(OC)c1 +CCC(=O)Nc1cccc(C(=O)Nc2ccc(Nc3cc(-c4[nH]c(SC)nc4-c4ccc(F)cc4)ccn3)cc2)c1 +O=c1n(Cc2ccccc2)ccc2ncc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(F)cc4)c3)n12 +CCOC(O)=C1C(COCCN(C)C(=O)NC)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +O=S(=O)(Nc1c(F)c(F)c(NS(=O)(=O)c2ccc(F)cc2)c(F)c1F)c1ccc(F)cc1 +Cc1cc(C)c(-c2cc3cnc(N)nc3nc2NC(=O)NC(C)(C)C)c(C)c1 +Cc1ccc(NC(=O)c2ccc(C#N)cc2)cc1-n1c(C)nc2ccc(N3CCN(C)CC3)cc2c1=O +CC(C)(C)N1CCN(c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)CC1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1Br +CC(C)C(CN1CCC(c2ccccc2)CC1)NC(=O)C1Cc2ccc(O)cc2CN1 +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)NCc4ccccc4)cc3)cc2n(C)c1=O +Cc1ccc(C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)cc1N +Nc1nccn2c(-c3cccc(NC(=O)c4ccc(Br)cc4)c3)cnc12 +Cn1cc(-c2cc(NS(C)(=O)=O)cnc2Oc2ccccc2)c2cc[nH]c2c1=O +O=S(=O)(c1ccccc1)N(Cc1cccc(OC(F)(F)F)c1)c1sc2ccccc2c1Br +Fc1ccccc1Nc1nc2c(-c3nnc[nH]3)cccc2c2sccc12 +CN(CCc1ccccc1)C1C2C3CC4C2C(=O)C2C4C3C21 +Cc1ccc(CNC(=O)c2nc3ccc(-c4ccc(C5CCC(CC(=O)O)CC5)cc4)cn3n2)cc1 +CCCCNc1nc(NCCCC)nc(NCCc2ccc(S(N)(=O)=O)cc2)n1 +CC(C(=O)O)c1ccc(-c2cn3ccccc3n2)cc1 +CN(C)C(=O)N1C2CCC1CC(c1ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn13)C2 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCNC(=O)CNCC(=O)O)cc3)[nH]c2n(CCC)c1=O +N#Cc1ccc(CN(C(CCC(F)(F)F)C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)c(F)c1 +COc1ccc(-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c(N)c1 +CNC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1N2C +CCC(N)c1ccc(Cl)c(C(=O)c2ccc3c(c2)OCC(=O)N3)c1F +O=C(C=Cc1ccc(C=Cc2ccc3ccc(Cl)cc3n2)cc1)c1cc(-c2nn[nH]n2)ccc1O +CN(CC(CCN1CCC2(CC1)CC(=O)Nc1ccccc12)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 +O=C(OC12C3C4CC5C6C4C1C6C1(OCCCN12)C53)c1n[nH]c2ccccc12 +CCC1CC(=Cc2ccccc2Cl)C2=Nc3ccccc3CN21 +CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(NCCc3ccc(C(F)(F)F)cc3)c(Cl)c2)cc1 +Cc1csc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +Cc1ccc(NNC(=O)C(O)C(N)CSCC(C)C)cc1 +COc1cc(Br)cc(C2Nc3c(c(C)nn3C)C(=O)CS2)c1 +CCCc1nc(CC(NC(=O)c2cnc(C)cn2)C(=O)N2CCCC2C(N)=O)c[nH]1 +O=C(NO)c1ccc(NC2CCN(c3ccc(Cl)cc3)C2=O)cc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cnn(-c2cccc(OC(F)(F)F)c2)n1 +CCCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1cccc(Br)c1 +CCCc1c(OCCCN(C)c2ccc(CC(=O)O)c(C)c2)ccc2c(C(F)(F)F)noc12 +O=C1NOCC1NCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CC(C)c1c(Cl)sc2nc(O)c(-c3cccc(Oc4ccccc4)c3)c(O)c12 +COc1cc2c(cc1OC)C(=O)C(CCC1CCN(Cc3ccccc3)CC1)C2 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4ccccc4Cl)c3)cc12 +CCc1cnc(Oc2ccc(NC(=O)c3ncccc3N)cc2Cl)nc1 +Cc1cc2c(cc1Cc1ccc(C(=O)NCC3CCCC(Nc4nccc(NCC5CCCO5)n4)C3)o1)C(C)(C)CCC2(C)C +Cc1ccc(NC(=O)C(C)C)cc1C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 +Nc1ncnc2nc(-c3ccc(N4CCC(O)CC4)nc3)cc(-c3cccc(Br)c3)c12 +FC(F)(F)c1ccc(Nc2ncnc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +c1ccc(Cn2cc(-c3c[nH]c4ncc(-c5ccncc5)nc34)cn2)cc1 +O=C(O)c1ccc2oc(-c3cccc(C=Cc4ccc5ccccc5n4)c3)cc(=O)c2c1 +COc1cc2cc(CO)c(CO)c(-c3cc(OC)c(OC)c(S(C)(=O)=O)c3)c2cc1OC +Cc1cn(Cc2ccc(Cl)cc2Cl)c2c(-c3cc(NS(=O)(=O)c4ccc(Cl)c(Cl)c4)no3)cc(F)cc12 +CCCCc1ncc(C=C(Cc2ccc(OC)cc2)C(=O)O)n1Cc1ccccc1Cl +O=C(CCc1noc2c1ccc1c(F)c(O)ccc12)NC1=C(C(=O)O)CCCC1 +CCOc1c(C=CC(=O)N2N=Cc3ccccc3C2C=C(C)C)cc(Cc2cnc(N)nc2N)cc1OC +O=C(O)CC(Cc1csc(CCCc2ccc3c(n2)NCCC3)n1)c1ccc(Cl)cc1 +O=C(Nc1ccc(C(=O)N2CCN(c3cccnc3)CC2)cc1)N1Cc2ccccc2C1 +Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(C5CCOCC5)cc4n3Cc3ccccn3)cn12 +CCc1cccc(NC(=O)N2CCc3nc(-c4ccc5ccccc5c4)nc(-c4ccccc4C)c3C2)c1 +CC(O)(c1ccnc(-c2cccc3cc(C(NS(=O)(=O)C4CC4)c4ccccc4Cl)sc23)c1)C(F)(F)F +O=[N+]([O-])c1cc(I)cc(C#Cc2ccccn2)c1 +Cc1ccc(C2COc3cc4[nH]c(=O)cc(C(F)(F)F)c4cc3N2CC(F)(F)F)cc1 +O=C(O)C(CC1CCC1)N1CC(CN2CCC(c3nnc4ccccn34)CC2)C(c2ccccc2)C1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1nccc2ccccc12 +CCCN1CCC(COc2nc3ccccc3c3cccc(F)c23)CC1 +CC1(O)C(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)OC1n1cc(-c2ncon2)c2c(N)ncnc21 +Cn1cnc(S(=O)(=O)NCc2ccc3c(c2)C(Cc2ccccc2)C(CN2CCC2)CC3)c1 +O=c1[nH]n(CC2COC(c3ccccc3)O2)c(=O)c2ccccc12 +CCCCCCCCC#CCCCCCCCC(=O)OCC1(CO)CC(=CCC(C)C)C(=O)O1 +CN1CC=C(c2cc(C(F)(F)F)ccc2-c2cccc3c2CCN(S(=O)(=O)Nc2ncns2)C3)CC1 +CC(C)c1oc2ccccc2c1Cc1ccc(C(=O)NC2CCOCC2C(=O)NO)cc1 +COc1cc(-c2nnc(SCC(=O)OC3CCCCC3)o2)cc(OC)c1OC +COc1ccc(CNC(=O)CCCCCCCCC(=O)NCc2ccc(OC)c(O)c2)cc1O +Clc1ccc2c(c1Cl)CN(CCCCN1CCc3ccc(Cl)c(Cl)c3C1)CC2 +NS(=O)(=O)c1cccc(-c2n[nH]c3ccc(OCc4ccccc4)cc23)c1 +O=c1oc2ccccc2n1CCCCCCCN1CCN(c2ccccc2)CC1 +CN1C(=O)CCc2cc(-c3cncc(CSc4nc5ccccc5o4)c3)ccc21 +Cc1cc(F)ccc1CN1CCN(c2ccccc2C)C(=O)C1=O +Nc1cnc(-c2ccc(-c3ccccc3Oc3cccc(C(F)(F)F)n3)cc2F)cn1 +CC(C)Oc1ccnc2ccc(C#CCNC(=O)c3cccn(Cc4ccc(F)c(F)c4)c3=O)cc12 +CC1CN(CCOC(C)(C)C)c2ccccc2C(C)N1C(=O)Nc1cccnc1 +COC(=O)Cc1cccc(NC(=O)C2(N(C)C)CCN(c3ncnc4[nH]c5c(c34)CC(F)(F)CC5)CC2)c1 +Cc1cc2n[nH]c(=O)n2c2cc(-c3cccc(CO)c3)ccc12 +CCN(CC)Cc1ccc(C=Cc2cc(-c3cc4c(=O)[nH]cnc4[nH]3)ccn2)cc1 +Cc1ccc(C(=O)Nc2cc(OCCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCSCC3)nc12 +Oc1ccccc1-c1nc(NC2CCCNCC2)c2ccccc2n1 +O=C(Nc1ccc(C(=O)N2CCCc3c(S(=O)(=O)O)[nH]c4cccc2c34)cc1Cl)c1ccccc1-c1ccccc1 +CC(C)(C)c1cc(N2CCN(CCCCNC(=O)c3cn4ccccc4n3)CC2)nc(C(C)(C)C)n1 +O=C(NCC(NCC1NCC(O)C1O)c1ccccc1)c1ccccc1Br +COc1cc(N2Cc3ccc(Sc4ccc(F)cc4)nc3C2=O)ccc1OCCN1CCCC1 +COc1ccc(-c2cccc3c2CCC2C3c3cc(O)c(Cl)cc3CCN2C)cc1 +COc1ccc(C)cc1-n1c(-c2ccc(Cl)cc2)cc2c1CC(C)(C)CC2=O +N=C(N)NCCCC(NC(=O)c1ccc2ccccc2n1)C(=O)NCc1ccc(C(F)(F)F)cc1 +COc1ccc(Nc2cc(Oc3cc(C)c(C)nc3-c3ccccn3)ccn2)cc1 +O=c1c2c(O)cc(O)cc2oc2oc3cc(O)ccc3c12 +CC1CN(c2ccc3[nH]c(-c4n[nH]c5ccc(OC(C)c6c(Cl)cncc6Cl)cc45)nc3c2)CC(C)N1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)c(F)c3)nc(CO)c12 +CC(C)C1=C(C(=O)N2CCOCC2)SC2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21 +CC(C)CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CN2CCCC2)cn1 +O=C(C1C=C2c3cccc4[nH]cc(c34)CC2N(C(=O)Nc2ccccc2)C1)N1CCOCC1 +CN(C)CCOc1ccc(Nc2nccc(-c3ccc(N4CCCC4)c(C#N)c3)n2)cn1 +O=C(NCCO)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +Cc1c(F)c(Oc2cccc(CC(=O)N(C)C)c2)nc(Oc2cccc(C(=N)N)c2)c1F +O=C(Nc1ccc(Cl)cc1)c1cccc2cc(Oc3ncnc4[nH]ccc34)ccc12 +CCN1CCN(C(=O)C2CCc3c(sc4ncnc(Nc5ccc6[nH]c(=O)sc6c5)c34)C2)CC1 +CC(C)C(C(=O)NO)N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1 +COc1ccc(-c2c(C(=O)NC3CCN(CC4CC4)CC3)noc2-c2cc(Cl)c(O)cc2O)cc1 +CCCOCCn1c(=O)c(NCC(=O)N2CCOCC2)nc2ncc(-c3ccc(OC)nc3)cc21 +CCCc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 +CC(CC(Cc1ccc(-c2ccccc2)cc1)NC(=O)c1nnn[nH]1)C(=O)O +CCC(CC)(NC(=O)c1ccc(N(CC(F)(F)F)CC(F)(F)F)c(OCC2CC2)n1)C(=O)NC +CCc1nc2c(NC(C)=O)c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 +CCOP(=O)(c1ccc(-c2ccccc2)cc1)N1Cc2ccccc2CC1C(=O)NO +CN(C)C(=O)c1ccc(-c2ccnc3c2c(C=C2Oc4cccc(O)c4C2=O)cn3C)cc1 +O=C(NCC1CC23CCN(CC4CC4)C(Cc4ccc(O)cc42)C3(O)CO1)c1ccccc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2)n2c1COCC2)c1ccccc1 +O=C(Nc1ccc(O)c(O)c1)c1cc(O)c(O)cc1Br +CC1CCN(CCCCCCCCCCCC(=O)Nc2cc(CO)cc(Nc3ccnc4cc(Cl)ccc34)c2)CC1 +CCCS(=O)(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1 +Cc1cc(C#N)cc2nc(-c3ccc(NC(=O)CN4CCN(c5ccccc5Cl)CC4)cc3)oc12 +Cc1ccc(-c2nc3cc(N4CCCC4)ncc3[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +Cc1ccc2c(ccn2-c2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c1 +COc1ccc(-c2nc3c(NCCCNC(=O)c4cccs4)c(Br)cnc3[nH]2)cc1 +Cc1cccc(-c2oc(C3CC3)nc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 +O=C(NCCCCN1CCCC1)C1C(C(=O)NCc2ccc(Br)cc2F)C2C=CC1C21CC1 +CCN1C(=Cc2ccc3cc(OC)ccc3[n+]2CC)Sc2ccc(NC(C)=O)cc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(NCC2CC2)CC1 +COC(=O)c1ccc(C)c(NS(=O)(=O)c2ccc(OC)cc2)c1 +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(CCc3nccn3C)CC2)cc1 +COc1ccc(Nc2nc(-c3ccc(C)cc3)c(C(=O)Nc3sc4c(c3C(N)=O)CCCC4)s2)cc1 +O=S(=O)(c1cccc(F)c1)n1cc(C2=CCCNC2)c2ccccc21 +CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(C#N)c2)cn1 +CC(C)(C)OC(=O)N1CCC(N(C(=O)c2ccc(-c3ccc(C#N)cc3)cc2)C2CC2)CC1 +O=C(O)C(=Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)NC(=O)c1cccnc1Cl +NS(=O)(=O)c1ccc(NCC(=O)Nc2nc3ccc(S(N)(=O)=O)cc3s2)cc1 +Cc1cc(-c2n[nH]c(-c3ccnc(C#N)c3)n2)ccn1 +Cc1cnc2c(C(=O)NCC3CCN4CCCC34)cc(Cl)cn12 +COc1ccc2c3c1OC1CC(O)C=CC31CC[N+](CCCCCCCCN1C(=O)c3ccccc3C1=O)=C2 +O=c1[nH]c2ccccc2n(C2CC3C=CC(C2)N3C2C=CCCCCC2)c1=O +Cc1c(Nc2c(C#N)cncc2C=Cc2cccc(CN3CCCCC3)c2)ccc2[nH]ccc12 +O=C(c1nc2ccccc2[nH]1)N1CCC(Oc2ncccc2C2CCOCC2)C1 +CCc1nc(N)nc(N)c1-c1ccc(NC(C)c2ccccc2)c([N+](=O)[O-])c1 +NC(N)=NCCCC(N)C(=O)NCC1OC(OC2C(N)CC(N)C(O)C2O)C(N)C(O)C1O +O=C(Nc1ccc(Cl)cc1C(=O)O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 +O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccc(C(F)(F)F)cc12 +c1ccc(C23CCCC(OOC(C4CCCCC4)OO2)O3)cc1 +COc1ccccc1CN1CCC(N2CC(c3ccccc3)(c3ccccc3)NC2=O)CC1 +CC(=Cc1ccc(Oc2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cc1)C(=O)O +CC1C2Cc3ccc(O)cc3C1(C)CCN2CCN1CCCCCC1 +Cc1ccc(C2CC(NC(=O)Nc3cccc(Cl)c3)C(=O)N(CC(=O)NC(C)(C)C)c3cc(C)ccc32)cc1 +Cc1cccc2cc(Cn3nc(-c4cc(O)cc(F)c4)c4c(N)ncnc43)n(C3CC3)c(=O)c12 +CC(C)C(NC(=O)CC(C(=O)NCC(O)C(Cc1ccccc1)NC(=O)OCc1ccccc1)C(C)(C)C)C(C)C +Cc1ccccc1NC(=O)C(Cc1nc2ccc(C(=O)c3ccccc3)cc2nc1O)=NNC(=O)c1ccncc1 +Cc1nc2ccccc2n1-c1ccc(C(=O)N2CCC(N3CCCC3)C2)cc1 +CC(=O)NCC1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +N#Cc1ccccc1-n1c(-c2nonc2N)nc2ccccc21 +Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=O)c5cnn(-c6ccccc6)c5-c5ccsc5)cc4F)c3s2)c1 +C=C(C)C1CCC2(C(=O)N3CC(O)C3O)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC(C)(C)C(NC(=O)C(CCCc1ccccc1)CC(=O)NO)C(=O)NC(c1ccccc1)c1ccccc1 +COC1CN(C)CC1NC(=O)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1 +CC(N)C(=O)N1CCC(CC(=O)N2CCC(C3c4ncc(Br)cc4CCc4cc(Cl)cc(Br)c43)CC2)CC1 +O=C1NCc2c1c1c(c3c2c2ccccc2n3CCCO)Cc2ccccc2-1 +N=C(CCCCc1nnc(NC(=O)Cc2cccc(OCCCO)c2)s1)CCC(=N)NC(=O)Cc1ccccc1 +CC1NOC(C)C1c1ccc2c(c1)CN(C)CC2c1ccc2ccccc2c1 +N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(OC(F)F)ccc12 +Fc1cc(F)cc(CNc2cccc(-c3cc(NC4CCNCC4)ncc3Cl)n2)c1 +CCOC(=O)C=Cc1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(Br)cc1 +CCOc1cc(NC(=O)CCCCCCC(=O)Nc2cc(-c3ccccc3)ccc2N)cc2c1OCC([N+](=O)[O-])=C2 +O=c1c(O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 +CS(=O)(=O)c1ccc(C2SCC(=O)N2c2ccccc2)cc1 +Cn1cc(-c2cnc(N)c(C(=O)NCc3cc(F)ccc3F)c2)cn1 +Cc1cccc(NC(=O)Nc2ccc(-c3c(CCC(N)=O)sc4ncnc(N)c34)cc2)c1 +COc1cc2ncc(C(N)=O)c(Nc3cc(F)ccc3F)c2cc1OC +Cc1ccc(C(=O)Nc2cc(CN3CCCCC3)cc(C(F)(F)F)c2)cc1C#Cc1cnc2ccnn2c1 +CC1(CNc2nc(-c3cc(NC4CCC(N)CC4)ncc3Cl)ccc2F)CCOCC1 +Cc1cc(C)c(CNC(=O)c2cc(C#N)cc3c2CCN3C2CCCC2)c(=O)[nH]1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)O)cc3)c(Br)c2n(CCC)c1=O +[N-]=[N+]=Nc1cccc(COC(=O)NCc2ccc(C(=O)Nc3cc(-c4ccccc4)ccc3N)cc2)c1 +CCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCCC3COC)cc(Br)c21 +O=C(CN1C2CCC1CC(c1cccc(O)c1)C2)C1CCCCC1 +CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(O)c(C(=O)O)c1 +CCn1c(Cc2c[nH]c3ccc(OC)cc23)n[nH]c1=S +O=C(c1cccc(CN2CCN(c3ccc4ccoc4c3)CC2)c1)N1CCCCC1 +Cc1cc(OCCN2CCOCC2)nn1-c1ccc(Cl)c(Cl)c1 +COc1cc(C=CC(=O)C=Cc2ccc(N(C)C)cc2)cc(OC)c1 +Cc1noc(C)c1Cn1cc(N2C(=O)NC(CC3CCCC3)C2=O)cn1 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4C[S+]([O-])Cc4ccccc4)C(C2)N(CC2CC2)CCC315 +Fc1ccccc1C(Cc1ccccc1OC(F)F)N1CCNCC1 +CC(=O)NC(C)CCc1ccc(Oc2ccc(OCC3CCC3)cn2)cc1 +COc1cc(F)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +COc1ccc(C=CCN(C)Cc2cccc3cc[nH]c23)c(F)c1 +NC(=O)Nc1cc(-c2ccnn2-c2ccccc2Cl)ccn1 +CC(Cn1ncc2c(Nc3cccc(O)c3)nc(SCCN3CCOCC3)nc21)c1ccccc1 +COc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)c(Cl)c1 +c1ccc(-c2nnc3c4ccccc4c(OCC4CCNCC4)nn23)cc1 +CCCOc1ccc2c(c1)C(=O)N(CCC(NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC)C(=O)O)C2=O +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C(=O)NC1CC1N +Cc1nc(NCC(F)(F)F)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CCc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc3c(c2)CCO3)ccc1OCCN1C(=O)CCC1=O +CCCCN(C)c1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +C=CCN1C(=O)C(C)(C)c2cc(-c3ccc(C#N)n3C)cc(F)c21 +CCN(CC)c1ccc(C(=O)N2CCCCc3ccccc32)c(Cl)c1 +CCOC(=O)c1ccc(OC(=O)c2ccc3c(c2)C(C)(C)CCN3C)cc1 +COc1ccc2c(c1)c(CCNC(C)=O)cn2Cc1ccccc1 +Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)cncc2F)nc1 +COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCCCN1CCOCC1 +COc1ccc2nccc(NC(c3ccc(Cl)cc3)c3ccc(CN4CCCC4)cc3)c2c1 +O=C(O)c1[nH]cc(C(=O)NCc2ccc(F)cc2)c(=O)c1O +COc1cc2c(cc1OC)C(=O)N1C=C(c3cccc(C(=O)NCCCN(C)C)c3)CC1C=N2 +CC(C)(C)OC(=O)N1CCCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)C1 +Cc1nc2cc(C3CC4OC4(C)CCCC(C)C(O)C(C)C(=O)C(C)(C)C(O)CC(=O)O3)ccc2n1C +O=c1[nH]c(=O)n(COCCO)c(Sc2ccccc2)c1C=C(c1ccccc1)c1ccccc1 +COc1cc2ncnc(Nc3cnn(CC(=O)Nc4ccc(N(C)C)cc4)c3)c2cc1OC +Cc1nc(-c2cc3cc(N)cc(C#N)c3[nH]2)sc1C(=O)O +CN(C)C1CCN(C(=O)Cn2c(-c3ccc(Cl)cc3)c(C3CCCCC3)c3ccc(-c4noc(=O)[nH]4)cc32)CC1 +CCCCc1nn(COc2ccc(Cl)cc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCCCCNc1cccc(CNc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NC(C)C=CCCCc1ccccc1 +Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cocn1 +O=C1C=C(c2ccc[n+]([O-])c2)S(=O)(=O)c2ccccc21 +CN=C(NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +CC(=O)Nc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccc3c(c2)OCO3)n1 +CC(C)CC(C=O)NC(=O)C(CO)NC(=O)OCc1ccccc1 +N=C(N)NCCCC(N)C(=O)NCCCCCCCNCCCCCNC(=O)C(CC(N)=O)NC(=O)Cc1ccc(O)cc1O +Cc1cccc(C2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)c1 +Cc1nc2ccc(Oc3ccc4c(c3)OCO4)nc2c(=O)n1CC1CCCN(C(C)C)C1 +Cc1ccc(S(=O)(=O)NC(Cc2cccc(C(=N)N)c2)C(=O)N2CCN(C(=O)OCc3ccccc3)CC2)cc1 +C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CC[N+](C)(C)[O-] +COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(Br)c(N)c2)c(OC)c1 +COc1cnc(Cl)c(Nc2ncnc3cc(OCCCN4CCOCC4)cc(OC(C)C)c23)c1 +COc1c(C2CCC2)ccc(-c2cnc3[nH]cnc3c2)c1F +O=C(c1nnc(-c2ccccn2)o1)C1CCc2cc(Oc3ccccc3)ccc2C1 +O=C(OCCCCCCCCCCCCCCCC[n+]1cccc2ccccc21)c1ccc(O)cc1O +O=C(NC1CCN(C(=O)CCc2cccnc2)CC1)C(c1ccc2ccccc2c1)C1CCCCC1 +COc1ccc(-c2nc(C(=O)N3CCCCC3)c(CN)o2)c2ccc(C(F)(F)F)nc12 +Cc1c(CCN2CCN(C(=O)Cc3cncc(-n4cnnn4)c3)CC2)ccc2c1COC2=O +Cc1ccc(C(=O)NCCCC[N+](C)(C)CCNC(=O)c2nc(Cl)c(N)nc2N)cc1 +CCN1CC(NC(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)nc4)ccc3n2)CC1=O +COC(=O)c1ccc(CNCC(C)C2CCC3=Cc4c(cc(C)oc4=O)OC3C2)cc1 +COc1ccc(CCNCC(O)COc2ccc(OCc3ncc[nH]3)cc2)cc1OC +c1ccc(Nc2ncnc3[nH]c(-c4ccccc4)nc23)cc1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(Cl)cc1-c1c[nH]nc1N +CCC(NC(=O)COc1ccccc1C)C(O)C(O)C1CCCN1C(=O)COc1ccccc1C +O=C(Nc1nc(-c2ccccc2)cn2cc(-c3ccccc3)nc12)c1cccs1 +Cc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccc(S(N)(=O)=O)cc2C)c(C)c1 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+COCCn1c2cnccc2c2cnc(Nc3ccc(N4CCNCC4)cn3)nc21 +NCCNc1cccc(-c2cc(NC3CCC(O)CC3)ncc2Cl)n1 +CC1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1ccc(-c2cscn2)cc1 +COc1cccc(CC2CCN(C(=O)c3nc4cc(O)c(O)cc4[nH]3)CC2)c1 +COc1cc(Nc2ncccc2C(=O)NCc2cn(Cc3cccc(Oc4ccccc4)c3)nn2)cc(OC)c1 +CCS(=O)(=O)c1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)c3[nH]ncc23)c1 +COc1ccc(-c2c(C)cccc2C)cc1COc1ccc(CCC(=O)O)cc1 +CN1C(=O)C(NC(=O)Nc2ccc(Cl)c(Cl)c2)N=C(c2ccccc2)c2ccccc21 +CCN(CCOC)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +CCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2n1)c1ccccc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(C4CCC4)c3F)C2)cc1 +Fc1ccc2onc(C3CCN(c4ccc(-n5ccnc5)nn4)CC3)c2c1 +CN(C1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1)C(CO)Cc1ccccc1 +NC(=O)c1ccc2c(n1)nc(NCc1ccccc1Cl)n2CC1COc2ccccc2O1 +C=CCN(C)CCCCCCOc1ccc2c(c1)c(C)nn2C +CC(C)N=C1SC(=Cc2ccc(CO)cc2)C(=O)N1c1ccccc1 +N#Cc1ccc2c(c1)CN(CCCCCCNC(=O)c1cc3ccccc3[nH]1)CC2 +COCCNC1CCC(Nc2cc(-c3cccc(NCC4CC(C)OC(C)C4)n3)c(Cl)cn2)CC1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1)CC2 +COc1cc2nc(NCCC3CCOCC3)nc(Nc3cnc(OC)c(C)c3)c2cc1OC +CN(C)CC(NC(=O)C1CC2CC2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)c1cccc(Cl)c1F +Cc1ccc(COc2ccc(NC(=O)NC(Cc3ccccc3)C(=O)NCCCN3CCOCC3)cc2)cc1 +c1cc(CN2CCCCC2)ccc1COc1ccc2c(c1)CCCC2 +Cc1ccc(S(=O)(=O)n2ccc(C(O)c3ccc(Cl)cc3Cl)c2)c(C)c1 +O=C(O)CCC(=O)N1CCc2cc(S(=O)(=O)N3CCN(c4cccc(Cl)c4)CC3)ccc21 +CC(=O)N1N=C(c2ccc(C)cc2)OC1c1ccc(Cl)c(Cl)c1 +Nc1c([S+]([O-])CCCCl)sc2nc(-c3cccs3)cc(-c3ccccc3)c12 +Cn1c(N2CCOC(c3ccc(NC4CCOC4)cc3)C2)nc(-c2ccncc2F)cc1=O +COc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)ccc1-c1cccc(-c2ccccc2)c1 +CN1CCCN(c2cncc(-c3cccc(C=CC(=O)O)c3)n2)CC1 +COc1ccc2cc(OC3CCN(c4ncnc5cc(OC)c(OC)cc45)C3)ccc2c1 +COc1cc(C(=O)Nc2ccc(C(=O)N3CCCCC3)c(O)c2)cc(OC)c1OC +CCCCCCC(=O)CCCCCCC=CCC(O)C(O)C(N)(CO)C(=O)O +O=C(NOC1CCCCO1)c1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 +CCc1ncnc(-c2ccc(C(=O)N3CCC(N(C)C)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +COC(=O)c1sccc1NC(=O)Cc1cccc2ncccc12 +O=C(CN1CCC(N2C(=O)OCc3cc(Cl)ccc32)CC1)Nc1ccc(Oc2ccccc2)cc1 +CC(=O)c1cccc(-c2nnnn2CCCN2CCC(Cc3ccccc3)CC2)c1 +Cc1ccsc1CNc1ncc(-c2ccc(CN(C)C)cc2)c2nncn12 +Cc1ncc(-c2nc(Nc3ccc(C(=O)N(C)C)cc3)ncc2F)n1C(C)C +CN1CCN(C(=O)c2ccc(-c3cc(Cl)c4c(c3)C3(CCCCC3)NC(=O)N4)cc2)CC1 +CN(C)CCNC(=O)c1cc(-c2ccccc2)sc1NC(N)=O +OCc1ccc(OCC(O)CNC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)cc1 +CC(C)CN(Cc1ccccc1)S(=O)(=O)c1ccc(-c2ccc(C(N)=O)cc2)cc1 +Cc1cc(Cl)ccc1NC(=O)c1cccc(Br)c1C(=O)NC(C)C +Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4CCC(S(=O)(=O)C(C)(C)C)C4)cc3)nn3cccc23)n[nH]1 +CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]ccc3c2C1 +Cc1cc2c(s1)C13CC1CN(C(=O)OC(C)(C)C)C3=CC2=O +O=C(Cc1ccccc1)OC(Cc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 +O=C(NC(=O)c1ccc(Cl)cc1Cl)Nc1cc(O)c(C(=O)O)cc1Cl +CC(C)NC(=N)c1ccc2oc(CCCc3cc4cc(C(=N)NC(C)C)ccc4o3)cc2c1 +CCCCN(C)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 +CS(=O)(=O)C1CCN(c2cccc3c2cnn3-c2ccnc(NC3CCC(O)CC3)n2)CC1 +CN1C(=O)C(NC(=O)c2cccc(Cc3ccccc3)c2)COc2ccccc21 +Cc1cc(OCCN2CCC(n3cnc4cccnc43)CC2)nn1-c1ccc(Cl)c(Cl)c1 +CCCc1nc(C)n2c(O)nc(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12 +CN1CCN(c2ccc(Nc3ncc4ccc(-c5ccccc5N(C)S(C)(=O)=O)n4n3)cc2F)CC1 +CN(C)c1ccc(C=NNc2ccnc3cc(Cl)ccc23)cc1 +COc1cc(OC)c2c(c1)OC(=Cc1ccccc1O)C2=O +COc1ccccc1N1CCN(CCOc2ccc3nn[nH]c3c2)CC1 +O=C(COc1ccccc1)N1CCCCC1c1nc(-c2cccc(B(O)O)c2)no1 +COc1ccc(F)cc1-c1noc(-c2ccc(N3CCCCC3C)c(C(F)(F)F)c2)n1 +COc1ccc(-c2nnc(Nc3ccc(Oc4ccccc4)cc3)c3ccccc23)cc1 +N=C(CCc1ccc(Cc2c[nH]cn2)cc1)NCc1ccc(Cl)cc1 +Cc1cccc(C)c1Nc1ncc(-c2ccc(OCCN3CCOCC3)cc2)n2cncc12 +COc1ccc(C2(c3ccccc3)C(c3ccccc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1 +O=C(C1CCCN(c2ccc3nc(-c4ccnc(C5CC5)n4)[nH]c3n2)C1)N1CCOCC1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC(F)(F)F)CC3)c(OC)c2)c1C#Cc1ccc(N)nc1 +Cc1ccc(OCC(O)CN2CCCCC2)c(C(=O)CCc2ccccc2)c1 +O=C(O)c1ccc2c(c1)nc(Nc1ccc(Cl)c(C(F)(F)F)c1)c1ccncc12 +Cc1nc(NC(C)c2cccc(-c3cnc4c(c3)OCCN4C)c2)cc(-c2ccc3occ(C)c3c2)n1 +Cn1cc(-c2ccc(-c3cncc4ccc(C(=O)N5CCC5)nc34)cc2)cn1 +CCC1c2ccccc2-c2c([nH]c3ccccc23)C(=O)N1C +CC(C)(O)CNC(=O)c1cc(Cl)ncc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +COc1cc2c(cc1Cl)NC(NC(C)C)=NS2(=O)=O +O=C(C1CC1c1ccccc1)N1CCN(C2CCCCC2)CC1 +O=C(c1ccc(-c2cnc3ccc(NCC4CC4)nn23)cc1)N(Cc1cccc(Cl)c1)CC1CC(F)CN1 +CCCN1CCC2c3cccc(OS(=O)(=O)C(F)(F)F)c3CCC21 +CS(=O)(=O)c1cnc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 +OCC1C(O)C(O)C2CSC(=NCCCCCCCCCc3ccccc3)N12 +c1nc(N2CCC(COCCN3CCCC3)CC2)c2c(-c3ccc4c(c3)OCO4)csc2n1 +C=CC(=O)Nc1cccc(CNc2nc(Nc3cnn(C(C)(C)COC)c3)ncc2Cl)c1 +Cc1ccc(Oc2ccc(N(CC(Nc3cccc(F)c3)C(=O)NO)S(C)(=O)=O)cc2)cc1 +CCCS(=O)(=O)CCC12CCC(c3nnc(-c4ccccc4C(F)(F)F)n3C)(CC1)CC2 +NCc1cccc(-c2cc3c(cc2F)c(=O)c2c(=O)[nH]sc2n3C2CC2)c1 +Cc1ccc(NC(=O)N2CCC(CN3CCC(c4noc5cc(F)ccc45)CC3)CC2)cc1 +O=C(O)c1cc(-c2ccccc2)c2ccc(OCc3c(Cl)ccc(Cl)c3Cl)cc2c1 +CC(C)(CCCO)NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1 +O=C(O)C1=Cc2c(ccc(Cl)c2Sc2ccccc2)OC1C(F)(F)F +O=C(Nc1cccc(OC(F)(F)C(F)F)c1)c1ccc(N2CCCC2)c(C(F)(F)F)c1 +Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(Cl)nc(C(C)(C)C)c1 +CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(F)cc3)c2)CC1 +COCCn1cc(C#N)c2cc(-n3cc(C(=O)O)c(C)n3)ccc21 +Cc1ccc(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C)n2)nc1 +CCCC(CO)Nc1nc(C)nc2c1c(C)nn2-c1ccc(OC)cc1C +COc1ccc(CNC(=O)c2ccc(C)c(NC(C)=O)c2)c(C(F)(F)F)c1 +CCc1nc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)no1 +N#Cc1ccc(-c2cc3c(o2)C(=O)Nc2ccc(C4CCNCC4)cc2C3)cc1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CN(C(c2ccccc2)c2ccccc2)S(C)(=O)=O)CC1 +COCCOc1cc2nccc(Nc3ccc(Cl)cc3F)c2cc1OC +CC(C)OC(=O)C1=CN(C(=O)c2cccc(F)c2)CC(C)(C)c2cc(C#N)[nH]c21 +Cc1cc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)cn2CC(CO)O3)no1 +CC(c1ccc(S(=O)(=O)c2ccccc2)cc1)N1CCN(C)CC1 +C=C(C)CNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(NCCC)c3F)C2)cc1 +O=C1C=CC2(C=C1Cl)OCC(c1cccc(Br)c1)O2 +Cc1ccc(-c2ccc3c(c2)C=CS(=O)(=O)O3)cc1 +FC1(F)CCN(c2nnc(N3CCC(N4CCCCC4)CC3)s2)C1 +COc1cccc(CC(=O)n2c3cc(=O)n(Cc4cccnc4)c(C)c3c(=O)n2-c2ccccc2)c1 +O=C(NOCC(O)CO)c1ncncc1Nc1ccc(I)cc1F +Cn1nc(N2CCCC2)nc1CCc1nc2c(Br)cc(C(F)(F)F)cn2n1 +CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCN(Cc3ccncc3)C2=O)CC1 +Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1 +CCN(CC)C(=O)C1C=C2c3cccc4[nH]cc(c34)CC2NC1 +Cc1ccc(N2CCN(CCN3C(=O)CC4(CCCC4)CC3=O)CC2)c(C)c1 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+CCCc1n[nH]c2c1C(c1ccc(C)cc1)c1c(nc3c(c1N)CSCC3)O2 +O=C(CCCCCCc1ccccc1)c1ncc(-c2cscn2)o1 +Nc1nc(Nc2cccc(Br)c2)c2cc(CCc3ccccn3)[nH]c2n1 +NC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cc(F)cc(Cl)c1 +COC(C)(C)CCOC(=O)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O +CC1CCCN1C1CCC(c2ccc(NC(=O)c3ccccc3OC(F)(F)F)cc2)C1 +COc1ccc(-c2cc(-c3ccsc3)c(=O)n(C)c2-c2ccncc2)cc1 +CC(C)S(=O)(=O)NC1COCC1c1ccc(-c2ccc(F)nc2)cc1 +CSc1c(Cl)nc(N2CCN(C)CC2)nc1Nc1ccccc1 +CCCc1nc(C)c2c(NS(=O)(=O)C(F)(F)F)nc3ccc(OC)nc3n12 +O=S(=O)(Nc1ncns1)c1ccc2c(-c3ccc(C(F)(F)F)c(Cl)c3)nccc2c1 +CCCCc1ccnc(NC(=O)C2(CC(CCC)C(=O)O)CCCC2)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCc4cccnc4)c3)C2)cc1 +CC(=O)NCC(C=O)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +Cn1c(C(C)(C)C)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O +O=C(CCCCCC(NC(=O)c1ccc(Br)cc1)C(=O)NCc1ccncc1)NO +FCC1OC2(CCN(Cc3ccc(F)cc3)CC2)c2ccccc21 +CCc1ccc(Cn2cnc3c(N(C)C)nc(Cl)nc32)cc1 +NS(=O)(=O)c1ccc(C(=O)Cn2cnc3ccccc32)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NC3CCC(N(C)C)CC3)c2cn1)c1ccccc1 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3cc(Cl)ccc3[nH]2)o1 +O=C(c1nccc2[nH]cnc12)N1CCC(F)(F)C(Oc2ccc3ccccc3n2)C1 +CN1CC(Cc2ccccc2)(c2ccc(F)c(OCCN(C)S(=O)(=O)c3cn(C)cn3)c2)C1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(CS(C)(=O)=O)cccc4n3)c(C)c12 +CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2 +O=C(O)c1ccc(C2(NC(=O)C3CC4CC4N3Cc3ccc(C(F)(F)F)cc3)CC2)cc1 +Oc1ccc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1 +NC1CC(N2Cc3nn4cccnc4c3C2)CCC1c1cc(F)ccc1F +COc1ncc(C(F)(F)F)cc1Cn1cc(C(=O)NCCO)c2ncc(C)cc21 +COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3-c3ccccc3F)CC12C +CC(c1ccc(C(F)(F)F)cc1)N1CCC(NC(c2cccnc2)c2ccc(Cl)cc2F)CC1 +CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3ncnc4[nH]ccc34)cn2)C1 +CCc1ccc(N2CC3CN(C(=O)Nc4ccc(OC(F)(F)F)cc4)CC3C2=O)cc1 +Cc1csc2cc(C(C)Nc3ncnc(N)c3C#N)c(Cc3cccc(CN(C)CC(C)C)c3)c(=O)n12 +Cc1cn(Cc2ccc(O)c(C(C)C)c2)c2c(Cl)cc(OCC(=O)O)cc12 +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3cccc(C(=O)NCCN4CCCC4)c3)nnc2c1 +CC(C)c1ccc(CNc2ccc3c(c2)ncn3-c2ccccc2)cc1 +O=C(NCCc1nnn[nH]1)C1CCCN(C(=O)CCC2CCNCC2)C1 +Cc1nc2nc(C(=O)Nc3ccn(C)n3)cn2c(-c2ccc(Cl)cc2Cl)c1CN +CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)N=c1sc(C(C)(C)C)cn1CC1CCCO1 +O=C(c1c(F)cccc1F)N1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Cc1c(Cc2ccccc2)nnc(N2CCN(c3cnc(C(C)(C)O)cn3)C(C)C2)c1CO +CC(C)N1CCC(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1 +COc1nc2ccc(Br)cc2cc1C(c1ccccc1)C(O)(CCN(C)C)c1cccc2ccccc12 +O=C(C=Cc1ccc(C(=C2C3CC4CC(C3)CC2C4)c2ccc(O)cc2)cc1)NCCO +Cc1cc(NC(=O)CC(=O)O)c(C)c(C)c1Oc1ccc(O)c(C(C)C)c1 +Cc1csc(-c2ccc(N)c(NC(=O)c3ccc(CNc4ccncc4)cc3)c2)c1 +CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC1CCCN2C(=S)N(Cc3ccccc3)C(=S)CC12 +c1cnc2nc3c(c(NCCCCCCCNc4c5c(nc6ncccc46)CCCC5)c2c1)CCCC3 +CCCC(NC(=O)C1C2CCCC2CN1C(=O)C(NC(=O)OC(C)C)C(C)(C)C)C(=O)C(=O)Nc1ccccc1 +CCOC(=O)c1c2c(n3cccc(F)c13)C(=O)c1ncccc1C2=O +O=C(CN1CCCCC1)c1ccc(OCCCN2CCCC2)cc1 +O=C1CCc2cc(C(c3ccncc3)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc3c2N1CC3 +O=C1C(CC(F)(F)F)=CC(O)(CSc2cccc[n+]2[O-])N1CCNc1ccnc2cc(Cl)ccc12 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(F)cc1-c1cc(F)ccc1F +CC(Nc1cc(F)cc(F)c1)c1cc(C(=O)NCCF)cc2c(=O)cc(N3CCOCC3)oc12 +O=c1c2scc(-c3ccccc3F)c2ncn1-c1ccc(Cl)cc1 +COc1ccccc1CNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 +Nc1cccc2cc(C(=O)NC3CN4CCC3CC4)sc12 +CC(C)CNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +O=C(c1cccc2ccccc12)c1cn(CCN2CCOCC2)c2ccc(O)cc12 +N#Cc1cnn(C(=O)N2CCN(Cc3ccc4ccccc4c3)CC2)c1 +C=CCC1CCCC(NC(=O)C(S)Cc2ccccc2)C(=O)N1CC(=O)O +CCCCCc1ccc(NC(=O)C2Cc3ccccc3CN2C(=O)c2cc(Oc3ccccc3)ccn2)cc1 +Oc1c(-c2ncc(C(F)(F)F)cc2Cl)cnc2c(F)ccc(F)c12 +CC1(C)CN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5O)c4n3)nn2)CCN1 +OCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 +NC(=O)N1CC(S)C(NS(=O)(=O)c2ccc(Oc3ccccc3)cc2)C1 +Clc1ccc2c(Nc3ccc4oc(NCCN5CCCC5)nc4c3)ccnc2c1 +O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +CC(Cc1ccc(C#Cc2ccc(OCC3CC3)cc2)cc1)NC(=O)C1CC1 +CC(C)CC(C(=O)NC(Cc1ccccc1)C(N)=O)C(CSCC(=NO)c1ccccc1)C(=O)NO +COc1cc2c(cc1OC)CN(C(=O)CCC(=O)OCC#CCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1)CC2 +COc1ccc(COCc2cnc(Nc3cccc4[nH]ccc34)c(-c3nc(C)nc4[nH]cnc34)c2)cc1 +COc1cccc(N2CCC(Oc3ccc(N4N=C(C(F)(F)F)C(C)C4CC(=O)O)cc3)CC2)c1 +CC(Nc1ncc(F)c(N2C(=O)OCC2CF)n1)c1cn(-c2ccc(C(F)F)c(F)c2)cn1 +OCCCCc1nc(-c2ccc(F)cc2)c(-c2ccnc3[nH]c(-c4ccccc4)cc23)[nH]1 +COC(=O)C(C)(C)Cn1c(=O)[nH]c(=Nc2ccc(OC(C)C)nc2)n(Cc2ccc(Cl)cc2)c1=O +CCOC(=O)C1C(=O)C(=Cc2c[nH]c3ncccc23)OC1=Nc1ccc(CN(C)C)cc1C +COc1cccc(C(=O)c2sc(Nc3ccncc3)nc2N)c1 +CCCCCCc1ccc(C(=O)Nc2cccc3c(=O)cc(-c4nn[nH]n4)oc23)cc1 +CCOC(=O)N1CCC(c2ccccc2)(c2nccn2Cc2ccc(O)cc2)CC1 +CC(C)Nc1cc(-c2c[nH]c(C(=O)NC(CO)c3cccc(Cl)c3)c2)c(Cl)cn1 +ClC(Cn1ncc2c(NCc3ccccc3Br)ncnc21)c1ccc(Br)cc1 +CCNC(=O)c1ccccc1Nc1ncnc(Nc2ccc(CN)cc2)n1 +O=C(CCCCCNC(=O)c1ccc(-c2ccc(-c3cc(O)cc(O)c3)cc2)cc1)NO +Cc1cc(C)c(-c2[nH]c(CO)nc2C#N)cc1C(=O)N1CC(F)(c2ccc(C#N)cc2)C1 +CC(C)(C)C(=O)N1CCN(c2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2C#N)CC1 +Cn1nccc1-c1ccc(Cl)c(C(=O)NCC2(O)CCCCCC2)c1 +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCN1CCC2(C=Cc3ccccc32)CC1)C1CC1 +c1ccc(Nc2ncc3nnn(-c4ccccc4)c3n2)cc1 +CN(C)CCOc1ccc(-c2[nH]c3ncnc(NCC4SCCS4)c3c2-c2ccccc2)cc1 +CCNc1nc(C)c(-c2ccnc(Nc3ccc(CNC(C)=O)cc3)n2)s1 +CCOC(=O)CC(=O)NCC1OC(n2cc(Cc3ccc(C4CC4)cc3)c3c(Cl)cccc32)C(O)C(O)C1O +O=C(NCc1ccc(S(=O)(=O)N2CC3(CCOCC3)C2)cc1)N1Cc2ccncc2C1 +COc1cc(Oc2ccccc2F)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CC1=C(c2cn(C3CC(O)C(COP(=O)(O)O)O3)c(=O)[nH]c2=O)C(=O)c2ccccc2C1=O +Cc1cccc(F)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COc1cccc(C2=NNC(=O)C2=NNc2ccccc2Cl)c1 +Cc1ccc2c(c1)ncn2-c1ccc2[nH]cc(C3CCNCC3)c2c1 +Cc1c(C(=O)NCCN2CCN(C)CC2)cc(-c2ccc(-c3ccccc3)cc2)n1-c1ccc(S(N)(=O)=O)cc1 +Cc1cc(C)c2c(Nc3ccc(N4CCN(C)C(C)C4)cc3)c(C)c(C)nc2c1 +COc1cc2[nH]n(CC3(c4ccccc4)NC(=O)NC3=O)c(=O)c2cc1OC +COC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 +Nc1nc(CSc2ccccc2)nc2c1nnn2CC1CCCCO1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1Nc1ccc(N2CCC(N(C)C)C2)nc1 +CN(Cc1ccc(Cl)cc1)C(=O)C1(C)CCN1C(=O)c1csc2ccccc12 +O=C(NO)c1ccc2c(c1)CC(Nc1nccc(-c3cccnc3)n1)CO2 +NC(=O)C12CC3CC(C1)C(NC(=O)c1cccc(NS(=O)(=O)c4c(Cl)cc(Cl)cc4Cl)c1)C(C3)C2 +Cc1ccc(-n2c(C)nnc2SCC(=O)Nc2cccc(Cl)c2Cl)cc1 +CSc1cccc(N(CC(=O)O)C(=O)C(C)CSC(C)=O)c1 +COc1ccccc1C(Cc1coc2nc(N)nc(N)c12)C(C)C +O=C(NO)c1ccc(NC2CCN(c3cccc(Cl)c3)C2=O)cc1 +NS(=O)(=O)c1ccc(Nc2nc3ncnc(Nc4ccc(F)c(Cl)c4)c3s2)cc1 +Nc1c(N=Nc2ccc(-c3ccc(Cl)cc3)nc2)cc(S(=O)(=O)O[Na])c2ccccc12 +NS(=O)(=O)c1cc(S(N)(=O)=O)c(NSC(=S)N2CCOCC2)c(Cl)c1Cl +Fc1ccc(-n2c3c(c4cc(F)ccc42)CN(CCCCc2ccnc4ccccc24)CC3)cc1 +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(N)n[nH]c4c3)CC1)C2 +O=C(NC(CO)CO)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 +Cc1cc(=O)nc2nc(NC(=O)c3ccc(-c4ccc([N+](=O)[O-])cc4)o3)sn12 +CCN1CCN(C(=O)c2cn(C)c3cc(Nc4ncc(C(F)(F)F)c(NC)n4)c(Cl)cc23)CC1 +Nc1nc2c(cnn2CCc2cccc(-c3cccnc3)c2)c2nc(-c3ccco3)nn12 +Clc1ccc2nccc(N3CCC(CN4CCC(c5c[nH]c6ccccc56)CC4)CC3)c2c1 +CNC(=O)C(NC(=O)C(CCc1ccc(Cl)cc1)CP(=O)(O)Cc1ccc(Cc2ccccc2)cc1)C(C)(C)C +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(NS(=O)(=O)c4ccc(OC)cc4)cc3)ncc2F)c1 +COc1ccc(C2=NN(Cc3ccccc3)C(=O)C3CCCCC23)c2c1OC1(CCCC1)C2 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5oc(C#N)cc5c4)CC3)c2c1 +CCc1cc2c(C(F)(F)F)cc(=O)[nH]c2cc1NCC(F)(F)F +COc1cc2c(cc1OC)CN(C(=O)C1CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC1)CC2 +Cn1ncc2cc(-c3n[nH]c4ccnc(OC5CCOCC5)c34)ccc21 +Cc1[nH]c(-c2cc(N)ccc2Oc2ccccc2)c2c1C(=O)CCC2 +Cc1cc(C)c2c(c1)n(CC(=O)Nc1ccc3c(c1)CC1(C3)C(=O)NC(=O)N1C)c(=O)n2CC(N)=O +CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)C(O)C(O)C1O +COc1cccc(C#Cc2ccc3c(n2)CCN(C2CCCC2)C3=O)c1 +C#CCNc1ccnc2sc3c(=O)n(-c4ccc(OC)cc4)cnc3c12 +Cc1cc(C(=O)O)c(O)c(C(=O)C=Cc2cccc(C=Cc3ccc4ccccc4n3)c2)c1 +CCOC(=O)C1=C(C)NC(=Cc2ccn(-c3ccccc3C(F)(F)F)c2)C1=O +Nc1cc(Cn2c(C(=O)O)c(-c3ccc[nH]c3=O)c3cc(Cl)c(Cl)cc32)ccn1 +Nc1ccnc2c1C(=O)c1c(-c3ccccc3[N+](=O)[O-])ccnc1C2=O +Clc1ccc2c(NCCCN3CCN(CCCNCC4CC4)CC3)ccnc2c1 +O=C(O)c1ccn(S(=O)(=O)c2ccc3ccccc3c2)n1 +CC(C)(C)Cc1nc2cc(S(=O)(=O)Cc3ccccc3)ccc2n1CC1CC1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4cc5ccccc5s4)oc3C)ccc21 +CC1(c2ccc(OCCN3CCCCCC3)cc2)c2ccc(O)cc2CCN1c1ccccc1 +NC(COc1cncc(-c2cc3c(Cl)n[nH]c3cn2)c1)Cc1ccccc1 +O=C(Cn1c(=O)n(-c2nccs2)c2ccccc21)Nc1ccc2c(c1)CC1(C2)N=C(c2ccccc2)NC1=O +CC(=O)Nc1cn2cc(C=C3SC(=O)NC3=O)ccc2n1 +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4cocn4)o3)cc2Cl)CS1(=O)=O +CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)c1ccccc1 +Cc1ccc(C(=O)c2coc3c2C(=O)C(=O)c2ccccc2-3)cc1 +Cc1ccccc1-c1ccc2[nH]c(C=CC3CCCCC3)nc2c1 +CCOc1cc2c(-c3cccc(S(N)(=O)=O)c3)n[nH]c2cc1-c1cnn(C)c1 +COC(=O)c1cccc(-c2cnc(C(=O)C3CCc4cc(Oc5ccccc5)ccc4O3)o2)n1 +Cn1cc(C#N)c2ccc(NC(=O)Nc3ccccc3)cc21 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(-c4cccc(Cl)c4)ccc3nc2-1 +CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(c2cc(C)ccn2)CC1 +Cc1ccccc1C(=O)ON=C1CCS(=O)(=O)c2sccc21 +COCC(NC(=O)Nc1cc2[nH]nc(N3CC4CCC(C3)O4)c2cn1)c1ccccc1 +Cc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)cc1C +CC(Cc1ccc(F)c(F)c1)C(=O)NC1N=C(c2ccc3c(c2)OC(F)(F)O3)c2ccccc2N(C)C1=O +O=C(O)C1CCCN(CC[S+]([O-])C(c2ccccc2)c2ccccc2)C1 +COc1ccc(C=CC(=O)c2ccc(OC)c3c2OC(C)(C)C=C3)cc1N +CC(C)(C)c1ccc(CC(O)(CC(C)(C)c2ccccc2)C(=O)Nc2ccc3c(c2)COC3=O)cc1 +COc1ccnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4c(Cl)cnc(N)c34)c(OC)c2)c1 +NS(=O)(=O)c1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 +Cc1cc(N=c2[nH]c(=O)n(CCCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C +CC(OC1CN(C2=CC(=O)N(C)C2)CC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCCCCCC(C)(C)c1cc(NC(C)=O)c2c(c1)OC(C)(C)C1CCC(C)=CC21 +COc1ccc(C#N)c(S(=O)(=O)Nc2ccc(-c3nc(C4CC4)c4c(N)n[nH]c4n3)cc2)c1 +O=C(Nc1ccc(N2CCOCC2)cc1)c1cccnc1NCc1ccncc1 +Cc1cccc(C#Cc2ncn3c2COc2ccccc2-3)c1 +CC(C)COC(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +CN(C)S(=O)(=O)NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2 +Nc1cnc(-c2ccc(-c3ccccc3Sc3cnccn3)cc2F)cn1 +CNS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CN1CCOCC1)CCCC3)C(=O)N2 +CN1C(=N)NC(C)(c2sc(-c3ccnc(-c4cnco4)c3)cc2F)CS1(=O)=O +O=C(NC1CCC(c2cccc(F)c2F)CN(CCOC(F)(F)F)C1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1 +COc1cc(N(CC2CC2)c2ccc(F)c3ccccc23)cnc1C(=O)C1CC1C(=O)O +CCc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F +O=C(NCc1cccc(OCCOc2nc[nH]n2)c1)c1nc2scc(-c3cccc(Cl)c3)c2c(=O)[nH]1 +CCCCCNc1ncc(-c2ccccn2)c(NC2CCC(O)CC2)n1 +Cc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1C +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CC(O)CC(C)(C)O)CC(O)CC1O +COCc1nc2c(C(=O)Nc3ccccc3OC)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CNc1cc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)ccn1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(OC)cc1 +NC1CN(Cc2ccc(-c3csnn3)cc2)CC1C(=O)N1CCCC1 +N=C(N)c1ccc(COc2c(Cl)cc(C(=N)N)cc2Cl)cc1 +COc1cccc(C(=O)c2c(-c3ccccc3)[nH]c3ccccc3c2=O)c1 +Cc1ccc(CC(C)C(=O)N2CCN(c3ccc(C(F)(F)F)cc3C(N)CC(C)C)CC2)cc1C +COc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1NC1CCNCC1 +COc1cc(COc2ccc3c(c2)NCCN(C(C)C(=O)NO)S3(=O)=O)cc(OC)c1 +COc1ccc2nc(-c3noc(C4CCN(C(=O)CCC(F)(F)F)CC4)n3)sc2c1 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NC2CCOC2)cc1 +COCc1cccc(C=CC2C3CCCCC3CC3C(=O)OC(C)C32)n1 +CSCCC(C(=O)O)N(C)C(=O)c1ccc(CNc2cccnc2)cc1-c1ccccc1 +CN1CCN(c2cccc(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 +COc1cc(OC)c2nnc3c(C)nc(-c4ccccc4C)n3c2c1 +COc1ccc(C(=O)c2c[nH]c3c(OC)c(OC)c(OC)cc23)cc1O +CS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2-c2ccc3c(c2)OCCO3)cc1 +CCc1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)C(=O)O)cc1 +COc1cccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)c1 +CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2cccc(CNC(=O)CNC(=O)c3cccnc3)c2)n1 +CCOc1ccc2c(c1)NC(=O)Nc1cnc(C#N)c(n1)OCCC=CCO2 +CN(C)C(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccc(-c3ccccc3)cc21 +Cc1ncc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)cc2)cn1 +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(OCCOC(F)F)c2cn1)c1ccccc1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3cc(OC)c(OC)c(OC)c3)nn21 +CC(F)(F)c1n[nH]c2cc(NC(=O)NCc3ccc(F)cc3)ncc12 +CNC(=O)N1CC2C=C(c3cc4c(-c5cc(F)ccc5OC)ccnc4[nH]3)CC2C1 +COc1ccc(NC(=O)C(=O)Nc2ccc(OC)cc2C(=O)Nc2ccc(N3CCOCC3=O)cc2)cc1 +CCOC(=O)CCN1CCN(c2ccc3c(c2)C2CCN(C(=O)OCc4ccccc4)C3C2)CC1 +CC(CC(=O)Nc1cc(-c2ccnc3c(C(=O)c4cccs4)cnn23)ccc1F)C(F)(F)F +CCc1nc2cc(Cl)ccn2c1C(=O)NCc1ccc(N2CCC(c3ccc(F)cc3)CC2)cc1 +O=C1CC(N2CCN(c3ccc(O)cc3)CC2)C(=O)N1Cc1ccccc1 +CC1(O)C(O)C(COC(=O)NC2CCCC2)OC1n1cnc2c(NC3CCCC3)nc(Cl)nc21 +CCCCC(N)C(=O)Nc1ccc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OCc2ccccc2)cc1N +c1ccc(Cc2ccc(OCCn3cnc4cncnc43)cc2)cc1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(CO)c1ccc(Cl)c(F)c1 +CCCC(N)C(=O)N1c2ccccc2CC1c1ncc[nH]1 +O=C(CN1CCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)[nH]c23)c2oc3ccccc3c12 +Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc(Br)cc1 +CCNc1cnc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(F)cc4F)c3)cc2c1OC +CCc1c(O)ccc2nc3c(c(CC)c12)Cn1c-3cc2c(c1=O)COC(=O)C2(O)CC +Nc1ncc(-c2cccc(Cl)c2)nc1C(=O)NC1CCCC1 +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)C3CCCC3)ncc2c1 +C=CCc1c2c(cc(C(=O)OC)c1C(=O)OC)C1(C)CCCC(C)(C(=O)OC)C1CC2 +Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(-c3ccccn3)cn2)cc1 +Cc1cccc(C)c1CN1CCc2ccc(CC(=O)O)cc21 +CCc1nc2c(c(C(N)=O)n1)CN(C(=O)CCc1ccc(OC(F)(F)F)cc1)CC2 +CN1CCC(c2ccnc(Nc3cc(-c4ccc(OC5CCOCC5)c(C#N)c4)ccn3)c2)CC1 +N#Cc1nc(N2CCOCC2)nc(N(Cc2ccc3c(c2)OCO3)C2CCCCC2)n1 +CCSc1ccccc1-c1ccc(-c2nnc(C3(c4ccc(Cl)cc4)CCC3)n2C)c(Cl)c1 +CC1CCC(NC(=O)c2cc3cc(-c4ccc(F)cc4)cnc3n(CCN3CCOCC3)c2=O)CC1 +O=C1CCc2ccc(NC(=O)NC3CCOc4c3cccc4C(F)(F)F)cc2N1 +CS(=O)(=O)c1ccc(Oc2cc(OC3CCOCC3)cc(C(=O)Nc3nccs3)c2)cc1 +Cc1ccc(NN=C2CCC(C)n3c2ncc(C(=O)O)c3=O)cc1 +O=C(CCN1CCCCC1)Nc1ccc(NC(=O)CCN2CCCCC2)c2c1C(=O)c1ccccc1C2=O +CCc1c(Sc2ccc(Cl)cc2Cl)[nH]c2nc(N)nc(N)c12 +CC(O)(c1ccc(S(=O)(=O)c2cccc(Cl)c2)cc1)C(F)(F)F +CC(=O)NC(C)c1ccc(OC2CCN(c3nccc(N4CC5(CCC5)C4)n3)C2)cc1 +C=CC1CN2CCC1CC2C(c1ccnc2ccccc12)S(=O)(=O)O +COc1nccc2[nH]nc(-c3ccnc(N4CC(C)OC(C)C4)c3)c12 +O=C(NNC(=O)C(OCC=CBr)C(O)C(O)C(OCC=CBr)C(=O)NC1c2ccccc2CC1O)c1ccccc1 +Cn1cc2c(nc(N(Cc3ccccc3)Cc3ccccc3)n3nc(-c4ccco4)nc23)n1 +O=P(O)(O)OC1C(O)C(O)C(OP(=O)(O)O)C(OP(=O)(O)O)C1O +COc1ccc(-c2c(O)ccc3nc(-c4cc(-c5cnn(C6CCNCC6)c5)cnc4N)oc23)cc1 +O=C1OCC(c2ccc(C(F)(F)F)cn2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +O=C(NCc1ccc(F)cc1)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N2CCCCC2)c1=O +CCc1nc2c(-c3ccc(OC)nc3C(F)(F)F)ccnc2n1C(CC)C1CC1 +CCCCC[S+]([O-])c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N +Cc1oc(-c2ccccc2)nc1CCCc1ccc(CC(C(=O)O)n2nccn2)cc1 +Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccn2)cc1Nc1ncnc2cnc(NCc3ccccc3)nc12 +C=CC1OC(n2cnc3c(NOC)nc(Cl)nc32)C(O)C1O +CCCC(C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(C#N)cc1 +Cc1ccc2sc(C(=O)Nc3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)cc2c1 +CCCCCCN1CNC(=O)C12CCN(C1CCCCC1c1ccccc1)CC2 +Cc1cc(-c2nc(C(=O)Nc3cnn(C)c3N3CCC(N)CC(F)(F)C3)c(N)s2)ccn1 +CC(CO)(CO)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 +CC(C)(C)c1ccc(Nc2nc(N3CCCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CCn1nnc(C2OC(n3cnc4c(NCC5CC5)ncnc43)C(O)C2O)n1 +Cc1cccc(C(OC2CC3CCC(C2)N3C)c2ccccc2)c1 +CC(C)c1cccc2c1C(=O)N(COc1ccc(S(=O)(=O)N3CCOCC3)cc1)S2(=O)=O +COCCN1CCn2cc(C(=O)NCc3ccc(F)cc3)c(=O)c(O)c2C1=O +Nc1cccc(Cn2c(-c3ccc(Oc4ccccn4)cc3)ccc2-c2ccccc2Cl)n1 +CC(C)=CCn1c2c(ccc1=O)C(NCCc1ccc(F)c(F)c1)CCC2 +Cc1c2cc(-n3ccc(OCc4ccc(Cl)cc4)cc3=O)ccc2nn1C1CC1 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+O=C(c1n[nH]c2c1CN(CC1CC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 +Cc1c(O)cccc1C(=O)NC(Cc1ccccc1)C(O)C(=O)N1CSC(C)(C)C1C(=O)NC(C)(C)c1ccccc1 +c1cc2cc(-c3ccc(OC4CN5CCC4CC5)nn3)ccc2[nH]1 +CCc1nc(N)nc(N)c1-c1ccc(Cl)c(N=NN(CCOC(C)=O)Cc2ccc([N+](=O)[O-])cc2)c1 +O=CN1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +Clc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +CC(C)(Cc1nc(-c2ccc(O)cn2)no1)C(=O)NC1=C(C(=O)O)CCCC1 +CCCC1(CCC)CC(=O)C(C(c2ccccc2)C2CC2)=C(O)O1 +O=C(O)CCc1ccc(Nc2ncc3nnn(-c4ccccc4)c3n2)cc1 +CCN1CC(N(Cc2cc(F)ccc2Cl)c2ccc(C#N)c(Cl)c2)CC1=O +COc1nc(-c2ccccc2Cl)cc2nc(-c3csc(C(C)C)c3)[nH]c12 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2OC2CCCCC2)c2cc[nH]c2c1=O +CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1CC(F)(F)F +Cc1cccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCCC6)ccn45)cccc32)n1 +O=C(CC(Nc1ccc([N+](=O)[O-])cc1)C1CCCCC1)c1ccc(Br)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2cnc(NC3CCCC3)nc2)cc1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2c(Cl)c(Cl)ccc2o1 +CCCOC(=O)c1c(-c2ccc(F)cc2)nc(CC)c(C(=O)SCC)c1CCC 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+O=C1c2ccccc2C(=O)N1CCCCCCCCCN1CCN(Cc2ccccc2)CC1 +O=C(Nc1ccc(N(CCCl)CCCl)cc1)Nc1c2ccccc2nc2ccccc12 +COc1cc(C(=O)N2CCNCC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)n2ccnc2c1C(N)=O +O=C(O)C1CCC(O)(c2ccc(-c3ccccc3)cc2)C1 +Nc1nc2c(cnn2CCCc2ccc3c(c2)OCO3)c2nc(-c3ccco3)nn12 +Cc1ccc2nc(NC(=O)CNC(=O)c3nn(-c4ccc(F)cc4)c(=O)c4ccccc34)sc2c1 +C1=C(c2cnn3cc(-c4ccncc4)cnc23)CCC1 +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)C2=NOC(CCCCN=C(N)N)C2)C(=O)O)c(C)c1 +N#Cc1ccc2cc1Oc1ccc3c(c1)C(CC3)N1CCC(NCc3cncn3C2)C1=O +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3ccc(F)c(F)c3)ccc2[nH]1 +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2ccc(C(=O)OCC)cc2)C(C(=O)O)C1 +O=C1CC(C(=O)O)Oc2cc(COc3ccc(OCc4ccc5ccccc5n4)cc3)ccc21 +CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NN +CCCN1c2cc3c(cc2C2CCCCC21)c(C(F)(F)F)cc(=O)n3C +Cc1nsc(Nc2ncnc3ccc(Oc4c(F)cccc4S(C)(=O)=O)cc23)n1 +OC1(C(CN2CCNCC2)c2cc(Cl)sc2Cl)CCCCC1 +CN(C)c1ccc(C(F)(F)F)c(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(N)CC3)n2)n1 +Cn1nc(-c2ccc(F)cc2)c(-c2ccc3nc(NC(=O)c4ccnc(N5CCOCC5)c4)cn3n2)c1C1CCOCC1 +CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(C#N)ccc3F)cnc2N)CC1 +COCCCOc1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)ccc1OC +Cc1nc(C)c(-c2ccc3cc(CCN4CCCC4C)ccc3n2)s1 +NC1CN(c2cc(-c3cccnc3)ncn2)CC1c1cc(F)c(F)cc1F +O=C(c1cccc(O)c1)c1ccc(Sc2cccc(O)c2)s1 +Cc1n[nH]c2c(NCC(C)C)cc(NS(=O)(=O)c3cccc(-c4ccccc4)c3)cc12 +CC1(C)C2CC3OB(C(CCCCN)NC(=O)C4CCCN4C(=O)c4ccc(Cc5ccccc5)cc4)OC3(C)C1C2 +c1cnc(Oc2ccc(Nc3nc4ccccc4s3)cc2)c(C2CCCOCC2)c1 +CC1(O)CCC(c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCC(=O)N(Cc3cccc(F)c3)c3ccccc32)n1 +OCC(Nc1ncnc2oc(-c3ccccc3)c(-c3ccoc3)c12)c1ccccc1 +CC(C)CN(c1ccc(C(O)(C#Cc2cccc(C#N)c2)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1 +Cc1nnc2n1-c1sc(C#CCn3c4c(c5cc(Cl)ccc53)CCCCC4)cc1C(c1ccccc1Cl)=NC2 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(C(F)(F)F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +O=C(CCCCNC(=O)c1nc(-c2nccs2)sc1C1CC1)NO +N#Cc1cncc(N2CC(S(=O)(=O)c3ccccc3Cl)CC2C(=O)O)n1 +CCNc1nc2cc(OC)c(Cl)cc2nc1-c1cccc(C(N)=O)c1 +CCCNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)CC2C)c(=O)c1=O 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+CC(C)(C)Nc1cccc2c1SC(OCCCO)C(=O)N2 +O=C(c1cccc(F)c1)N1CCn2nc(COc3cccc(F)c3)cc2C1 +CC1CN(S(=O)(=O)c2cccc3ccccc23)C(C)CN1C(=O)C(C)(O)C(F)(F)F +O=c1[nH]c2cc(CN3CCOCC3)ccc2c2c1CCCN2 +COC(=O)C1CC(c2ccc(Cl)c(Cl)c2)C2CC(=O)C1N2C +CN(CCc1nc2ccccc2n1CC(=O)Nc1ccc2c(c1)CCC2)C(=O)c1ccc2ccccc2c1 +COc1cccc(Cc2noc(-c3[nH]c4ccccc4c3CCN(C)C)n2)c1 +CN(CCO)c1cc(C(=O)O)nc2c(-c3ccc(F)c(CO)c3)nc(N3CCOCC3)nc12 +O=C(Nc1ccc2c(c1)CCN2)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CCC(=O)N1CCCC2(C)C(CCC3(C)C4CC=C(n5ccnc5)C4(C)CCC23)C1 +FC(F)(F)Oc1cccc(-n2nnc3ccc(NC4CCOCC4)nc32)c1 +OCc1cccc(Oc2cccc(-c3c(-c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1 +CCN(CC)CCCC(NC(=O)CCOc1cc(-c2cc(Cl)cc(Cl)c2)nn1-c1ccc2ccccc2c1)C(C)C +NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1Cc1ccccc1C(F)(F)F)Cc1cc(F)c(F)cc1F +CC(C(=O)O)N(C)C(=O)c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1 +CC(=O)Nc1ccc(-n2c(-c3ccc(S(C)(=O)=O)cc3)nc3c2CCCC3)cc1 +CC(=O)c1ccc(-c2sc(NC(=O)NCCC(=O)NC(C)(C)C)nc2C)cc1 +O=C(NC1CC1)c1ccc(-c2cnc3c(NCc4cccs4)nccn23)cc1 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+CC(=NNC(=O)c1ccc(Cl)c(Br)c1)c1cc(Cl)ccc1O +COCCn1c(=O)c2c(nc(Cc3c(F)cccc3F)n2C)n(Cc2ccco2)c1=O +CC(C)OC(=O)Nc1cccc(-c2cccc3c(C(=O)c4cccs4)cnn23)c1 +c1ccc(-c2nn(-c3ccccc3)[n+](-c3ccccc3)n2)cc1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCC(F)(F)CC2)C1=O)c1ccccc1 +O=C(C1=C(c2ccc(CCCOc3c(F)ccc(F)c3Cl)cc2)CC2CNCC1N2)N(Cc1cccc(Cl)c1Cl)C1CC1 +Cc1nc(NC(C)c2cccc(OCC(C)(C)O)c2)cc(-c2ccc3occ(C)c3c2)n1 +CCCCCCC(=O)c1c2c(nc3ccc(OC)cc13)-c1cc3c(c(=O)n1C2)COC(=O)CC3(O)CC +c1ccc(-c2ccc(Oc3ccc(OCC4CCCCN4)cc3)cc2)cc1 +CC1(C2CCCCC2)NC(c2nc(-c3ccccc3)c[nH]2)Cc2c1[nH]c1ccccc21 +C=Cc1ccc(CN2CCC(NC(=O)CNC(=O)c3cc(C(F)(F)F)ccc3N)C2)cc1 +CN(C)Cc1cc(NS(C)(=O)=O)ccc1Oc1ccc(C(F)(F)F)cc1 +CCC1CN(C(=O)C2(C#N)CCC2)CC1Nc1c(C(N)=O)cnn2cc(-c3ccnc(Cl)c3)cc12 +COc1ccc(Cl)cc1Cc1c[nH]c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc12 +CC(O)C(NS(=O)(=O)Cc1ccccc1)C(=O)NC(CCC(N)=O)C(=O)NCc1ccc(C(=N)N)cc1 +O=C(NCc1cccc(OCCOc2nc[nH]n2)c1)c1nc2scc(-c3ccccc3)c2c(=O)[nH]1 +CS(=O)(=O)N1CCCC1c1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cc1 +Cc1ccc(-c2c(CN)c(CC(C)C)nc(C)c2C(=O)OCc2ccc(C(=O)O)cc2)cc1 +CC(C)c1nc(Nc2cc(C(=O)O)nn2C)nc(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +Fc1ccc(-c2ncn(CCCNCc3ccccc3)c2-c2ccncc2)cc1 +COc1ccc(NC(=O)Nc2ccc(-c3ccc(C(=O)NC(C(=O)O)C(C)C)cc3)nc2)cc1 +O=c1oc(N2CCOCC2)cc2c(-c3cccc(-c4ccccc4)c3)cccc12 +CCN(CC)CCn1[nH]c2c3cc(C)ccc3nc3c([N+](=O)[O-])ccc1c32 +COC(=O)c1c(O)cc(O)c(Cl)c1CCc1nccn1Cc1ccc(C)cc1 +CC1CN(c2ccc(C#Cc3ccccc3)cn2)C(=O)OC1(C)C +COc1ccc(-n2c(C)nnc2SCC(=O)Nc2ccc(C)cc2Cl)c2ccccc12 +O=C(NCc1cc(Cl)ccc1-n1cnnn1)C1CC2CC2N1C(=O)C(O)c1cccc(F)c1 +CC1(c2cccc3ccccc23)NC(=O)N(CCCc2c[nH]cn2)C1=O +COc1cccc(CCC2CN(Cc3c[nH]c4cc(F)ccc34)CCC2(F)F)c1 +O=c1[nH]nc(-c2ccc(F)c(Br)c2)c2c1CCCC2 +O=C(c1cn(CCN2CCOCC2)c2ccccc12)C1CCCCC1 +CN(C)C(=O)C1CCC(Oc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)n2)CC1 +C#Cc1ccc2[nH]c(C(=O)N3CC4CC45C3=CC(=O)c3ccccc35)cc2c1 +CCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OCCN1CCOC1=O)S(=O)(=O)c1ccc(OC)cc1 +Cn1nc(-c2ccc(C(=O)NC(C)(C)CO)cc2)sc1=NC1CCCC(O)C1 +CCCn1c(=O)c2c(nc3[nH]c(C(C)C)cn32)n(Cc2ccccc2)c1=O +CC1(C)CN(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c21 +Cc1c(C)c(CNc2ccccc2)c(C)c(C)c1CNc1ccccc1 +COc1ccc(CN2C(=O)CN(C(=O)c3cc4ccccc4o3)CC2Cc2ccccc2)cc1 +COCCNC1CCN(C(=O)N(C)C(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(c2ccc(F)cc2C)C1 +O=C(OC1CCCCC1)c1cnc(Oc2ccc3c(c2)B(O)OC3)cn1 +COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Br)nc2)cc1)n1ccnc1 +O=C1C(Cl)=C(Nc2ccc(CCO)cc2)C(=O)c2cnccc21 +CCCCc1nn2ncccc2c1-c1ccnc(Nc2ccc(N3CCN(C)CC3)cc2)n1 +CCc1c(Sc2ccccc2)n(COCc2cccs2)c(=O)[nH]c1=O +Nc1nc2cc(-c3ccc(CCCc4ccccc4)cc3)ccc2c(=O)n1CC1CCC(c2ccccc2)O1 +CN(C)CCCCNC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +COC(=O)C1(c2cccc(OCc3cccc(OC)c3)c2)CC1C(=O)NO +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)OC1CCCc2ccccc21 +O=C(Nc1ccc(O)c(Cl)c1)C1CCN(CC(=O)N2CCN(c3cccc(Cl)c3)CC2)C1 +CN1CC=C(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 +Cc1cn(-c2cc(F)c(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)cc2F)cn1 +CC1CCCN1CCCOc1ccc(C2=NNC(=O)C(c3ccccn3)C2)cc1 +CON=Cc1c(N)ncnc1Oc1ccc(NC(=O)NCCCCN2CCCC2)c(Cl)c1 +CCC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1 +Cc1csc(-c2cc(-c3cccn3C)c3n(c2=O)CCCc2ccncc2-3)n1 +CN(CCCc1cccc(Oc2ccccc2)c1)C(=O)CP(=O)(O)O +CCc1cc2c(=O)n(N)c(SCCCN3CCN(c4ncccn4)CC3)nc2s1 +Cc1onc(-c2ccccc2)c1CN1CCCC(NC(=O)N2CCc3[nH]nc(-c4ccncc4)c3C2)C1 +Clc1ccccc1-c1cccc(-n2nnc(-c3ccccn3)n2)c1 +O=C(Nc1ccc2c(c1)NC(=O)N(CCO)C2)NC1CC(CF)(CF)Oc2c(F)cccc21 +N#Cc1nc(N2CCC(S(=O)(=O)c3ccc(N4CCN(C5CC5)CC4)cc3Cl)C2)cc(C(F)(F)F)n1 +CSc1nc(NCc2cccnc2)c(C(=O)O)c(SCc2ccccc2)n1 +COC(=O)c1cnc(N2CCN(c3nnc(C(O)c4ccccc4)c(C)c3C)CC2C)cn1 +CCc1noc(C)c1C(=O)N1CCSC1=Nc1cccc(Cl)c1C +O=c1oc(OCCCCC2CCCCC2)c(Cl)c2ccccc12 +CC(C)CNC1=NC(=Cc2ccc3c(c2)OCO3)C(=O)N1C +COc1ccc2c(c1)CCC(=O)C2=Cc1ccc(Cl)cc1 +CC(=NNC(=O)c1cc(Br)ccc1O)c1cc2ccccc2s1 +CCC(=O)c1ccc(C(=O)c2ccc(N(CC3CC3)c3ccc(Cl)cc3)cn2)cc1C(=O)O +COc1ccc(-c2nc(C(C)Sc3nc(N)cc(N)n3)c(C)s2)cc1OCCF +CCOC(=O)CCC(NC(=O)c1ccc(CNc2ccc3nc(N)nc(N)c3c2)cc1)C(=O)OCC +CCC(CC)c1ccc(Cl)c2nc(Nc3c(C)cc(Cl)cc3Cl)n(C)c12 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNCC(C)=O +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(C(F)(F)F)n[nH]c4c3)CC1)C2 +CC(C)(C)c1ccc2c(c1)CC(NC(=O)Nc1cccc3scnc13)C2 +CC(=O)N(C)Cc1ccc(-c2cc(OCc3ncccc3C(N)=O)c3cccnc3c2)cc1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2CCC(=O)Nc1ccccc1 +CC(C[Si](O)(O)C(Cc1ccccc1)NC(=O)c1ccccc1)C(=O)N1CCCC1C(=O)O +Cc1ccn2ncnc(Nc3ccc4c(cnn4Cc4ccccn4)c3)c12 +Cc1ccc2c3c(ccc(N(C)Cc4ccc(S(=O)(=O)c5ccccc5)cc4)c13)N=C2N +CCC#CCOc1ccc(S(=O)(=O)N(C)c2c(C)cc(Br)cc2C(=O)NO)cc1 +O=C(NC(CCCCCCSSc1ccccn1)C(=O)Nc1ccccc1-c1ccccc1)OCc1ccccc1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccc(Br)o1 +Cc1cc(C)n2cc(CSc3nc(-c4ccccc4)cn3C)nc2n1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2ccccc2C1 +Cn1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CC(O)C3)n2)cn1 +Cc1nnc(CNc2cc(OCC3CC3c3ccc(OC(F)F)cn3)nn(C)c2=O)s1 +CCCOc1ccccc1C(=O)NC(=O)NC1CC2CCC(C1)N2C +c1ccc(CNc2nccc(-n3cnc4ccccc43)n2)cc1 +CC12C=CC(=O)CC1CCC1C2CCC2(C)C(O)CCC12 +CC(C)C1CCC(N(Cc2ccc(C(=O)NCCC(=O)O)cc2)C(=O)Nc2ccc(OC(F)(F)F)cc2)CC1 +O=C(C=Cc1ccc(O)cc1)CC(=O)C=Cc1ccccc1-c1cccc2ccccc12 +COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)cc1 +CSc1nn2cc(-c3nc4ccc(OC(C)C)cc4o3)nc2s1 +O=C1N(CCCCCOc2ccc(-c3ccc(Cl)cc3)cc2)CCN1c1ccncc1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CS(=O)(=O)c2ccccn2)no1 +CN1CCC(c2ccc(-c3nc4c(C(N)=O)cccc4[nH]3)cc2)CC1 +COc1cccc2c1CCC=C2CCCN1CCN(c2ccccn2)CC1 +CCCCC(=O)OCc1ccc(C(CN)C(=O)Nc2ccc3cnccc3c2)cc1 +O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2cc(F)c(F)cc2F)CC1 +CC(C)(C)NC(=O)Nc1cnc2ccc(N3CCCC3c3cc(F)ccc3F)nn12 +COCC(C)n1cc(C#N)c2cc(-c3nc(C)c(C(=O)O)s3)ccc21 +N#Cc1cc(F)cc(S(=O)(=O)c2sc3ncc(N)cc3c2-c2cccc(F)c2)c1 +FC(F)(F)c1nnc2c(Sc3ccccc3)nc3ccc(Cl)cc3n12 +Cc1cc(NC(=O)Nc2ccc(N(CCCl)CCCl)cc2)cc(Nc2c3ccccc3nc3ccccc23)c1 +COc1ccc(CN(Cc2ccc(SC)cc2)c2ccc3nc[nH]c3c2)cc1 +NC1CN(C(=O)c2ccc(-n3cncn3)cc2)CC1C(=O)N1CCCC1 +N#CCNC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COc1cc(Nc2cc(C#N)cn(C(C)c3ccc(F)cc3)c2=O)ccc1-n1cnc(C)c1 +CC1(COc2nc(C(=O)NC(C)(C)c3nccs3)ccc2N2CC(F)(F)C2)COC1 +CCOCCc1sc[n+](CCCCCCCCCCCC[n+]2csc(CCOCC)c2C)c1C +CC(C)=CCC=C(C)CCCC(C)=CCCSC(C)CCC=C(C)CCC1OC1(C)C +O=C(NCc1cccnc1N1CCCCC1)c1cncc(-c2ccc(Cl)cc2)c1 +Cc1noc(-c2cc3cc(-c4nc(C(=O)NCc5ccc(C(O)C(F)(F)F)cc5)[nH]c4C)ccc3[nH]2)n1 +COc1ccc(Cc2ccc3c(-c4cnn(C)c4)cc(C(N)=O)nc3c2)cn1 +c1ccc2c(c1)c1cc[n+]2CCCCCCCCCC[n+]2ccc(c3ccccc32)NCCCCCCCCCCN1 +COc1cccc(-n2cc(C(=O)N3CCN(c4ccc5cnccc5c4)CC3)nc2-c2ccc(C)cc2)c1 +COc1ccccc1OCCN1CCN(c2cnn(CCCCCN3CCN(c4ccccc4OC)CC3)c(=O)c2Cl)CC1 +COC(CCS(=O)(=O)c1ccc2ccccc2c1)C(=O)NC1CCCc2cc(CN3CCCCC3)ccc21 +Cn1ccc(Nc2ncnc3ccc(Oc4c(Cl)cccc4S(C)(=O)=O)cc23)n1 +COCc1cc2c3cccnc3cc(CCc3nc(-c4ccccc4)cn3C)n2n1 +O=C(O)C1=C(C(=O)Nc2c(F)cccc2F)CCC1 +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cc(C)cc(CN)c3)cc2N=C(N)C1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(CN2CCC(N)C2)CC1 +CN(C(=O)Cc1ccc(Cl)c(Cl)c1)C(CN1CCCC1)c1ccccc1 +CC(Nc1ncnc2[nH]c(-c3ccc(NC(=O)CCCC(=O)NO)cc3)cc12)c1ccccc1 +NC(Cc1cnc[nH]1)C(=O)N1Cc2[nH]c3ccccc3c2CC1C(=O)O +Cc1cc(C(N)=O)ccc1-c1cc(C(F)(F)F)nc2c(-n3cnc(-c4cnn(C(F)F)c4)c3)cccc12 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+Cn1nc(S(N)(=O)=O)sc1=NC(=O)CNCCNCC(=O)O +CC(Cc1ccc2c(c1)OCO2)CN1CC2CCCCC2C(C(=O)N2CCN(c3cccc(F)c3)CC2)C1 +O=C(Nc1ccc([N+](=O)[O-])cc1O)Nc1ccccc1Cl +Cc1ccc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)cc1Nc1ccc2c(c1)NC(=O)C2=Cc1ccc[nH]1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n3n2CCCC3)n1)C(C)(C)O +CCC1=CC2Cc3nc4cc(C)cc(C)c4c(N)c3C(C1)C2 +CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(-c3ccccc3S(N)(=O)=O)cc1OCC2 +CCC(NC(=O)c1cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2s1)c1ccccc1 +O=C(CNc1cccc(O)c1)Nc1nc2ccc3[nH]ncc3c2s1 +COc1c(OC)c2c(c(CCN(C)C)c1SC)Sc1c(OC)c(OC)c(SC)c(CCN(C)C)c1S2 +CCc1cc(-c2noc(-c3cc(C)c(CNCC(C)C)s3)n2)cc(C)c1OCC(O)CNC(=O)CO +COc1cc(F)ccc1-c1nc(Nc2cc(F)cc(CS(C)(=N)=O)c2)ncc1F +O=C(NO)C1CN(C(=O)c2ccccc2)CCCN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 +CC(C(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1)N1CCCC1 +CC(C)Oc1cccc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +CC(C)S(=O)(=O)Nc1ccccc1N1CCN(C(=O)C(CCCc2ccccc2)NC(=O)C(C)(C)N)CC1 +O=C(NC(C(=O)N1CCC2OCC(=O)C21)C1CCCCC1)c1cccc(-n2cnnn2)c1 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+CCCCn1c(=O)[nH]c2cccc3nc4c(c1c32)Cn1c-4cc2c(c1=O)COC(=O)C2(O)CC +CN(C)c1ccc(-c2cn(-c3ccc(OCCF)cc3)nn2)cc1 +Nc1nc2c(N)[n+]3cnc2n1C1OC(COP(=O)(O)OP(=O)([O-])OCC2SC3C(O)C2O)C(O)C1O +O=C(NCc1ccc(Cc2ccsc2)s1)C(O)C(O)C(=O)N1CCCC1c1cccc(Cl)c1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)N1CC2CN(CCC(NC(=O)C3CCCC3)c3ccccc3)CC2C1 +CS(=O)(=O)N1CC(C(=O)Nc2ccc(Cl)cc2)C(C(=O)Nc2c(F)cc(-n3ccccc3=O)cc2F)C1 +Oc1ccc2nc(-c3ccccc3)n(-c3ccccc3)c2n1 +CCCCCCCC#CC1(C(F)(F)F)CC(c2ccc(C)cc2)=C(c2cn[nH]n2)C(=O)N1 +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1ccccc1 +CCN1CCN(Cc2ccc(Nc3nccc(-c4sc(NC5CCCC5)nc4C)n3)nc2)CC1 +Cc1nc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C +Cc1cccc2c1Oc1c(cccc1C(=O)NCCN(C)C)O2 +CS(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CN(C(=O)Nc4cc(F)ccc4F)C3)cc2C(N)=O)cc1 +Cc1ccn2ncc(C=NN(C)S(=O)(=O)c3cc([N+](=O)[O-])ccc3C)c2c1 +COCCn1c(C)c(C)sc1=NC(=O)C1C(C)(C)C1(C)C +O=C(CCC1CCCCC1)NC(Cc1ccccc1)C(=O)N1CCCC1C(=O)N1CCCCC1 +CS(=O)(=O)Nc1ccc2ccc3ncc(-c4cccnc4)cc3c(=O)c2c1 +O=C(N1CCCCC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +Cc1cc(SCC(F)(F)COc2ccc(C(F)(F)F)cc2)ccc1OCC(=O)O +Fc1cccc(CNc2ccc(Cl)c(-c3ccnc4[nH]c(C5CCCNC5)cc34)n2)c1 +C=CC1CN2CCC1CC2C(OCc1cn(-c2ccc(Cl)cc2)nn1)c1ccnc2ccc(OC)cc12 +Cc1ncc(Cn2cc(CCOP(=O)(O)OP(=O)(O)O)nn2)c(N)n1 +CNC(=O)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 +COC(=O)c1cccc(NC(=O)Nc2cccc(C#N)c2)c1CN1CCC(Cc2ccc(F)cc2)CC1 +CCCCC1Nc2ccc(C(C)C)cc2C(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc2c(=O)cc3n(CCCN(C)C)c4ccccc4nc-3c2c1 +O=C(Nc1ccc(-c2nc3cc(NC(=O)C4CC4)ccc3[nH]2)cc1)c1ccccc1Cl +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(Cl)c(C)c3)nc(C(C)O)c12 +CC1CN(CCC(=O)C2CCCCC2)CCC1(C)c1cccc(O)c1 +Cc1cc(S(=O)(=O)NCc2ccccc2)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +Cc1c(C(=O)NC2CCN(C(=O)NC(C)C)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(C=CCN1CCCCC1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC1CCOC1 +NC(C(=O)N1CCN(c2ccc3[nH]ncc3c2)CC1)c1ccc(Cl)cc1 +NC1=NC(CF)(c2cc(Oc3ncccc3Cl)ccc2F)CC(C(F)(F)F)O1 +Cc1ccc(F)c(-c2nc(C(=O)Nc3cnn(C)c3N3CCCC(N)CC3)c(N)s2)c1F +CCCCOC(=O)NC(CNC(=O)CC1CC(c2ccc(C(=N)N)cc2)=NO1)C(=O)OC 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+COc1cc(C(=O)NCC(O)c2cccc(Cl)c2)ccc1-c1cn[nH]c1 +O=C(c1cc(Cl)ccc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncon2)c1 +Cc1noc(C)c1S(=O)(=O)NC(=O)COc1cccc2[nH]cc(S(=O)(=O)c3ccc4ccccc4c3)c12 +COc1cc(C=C2CCCN3C2=NOC3(c2ccc(F)cc2)C(C)O)ccc1-n1cnc(C)c1 +COc1cc(OC)c(C(=O)C=Cc2cccc([N+](=O)[O-])c2)c(OC)c1 +COCCN(Cc1ccc(-c2ccc(Cl)cc2)cc1)C(=O)Cn1cc(Cc2cnn(C)c2)c(=O)nc1SCc1ccc(F)cc1 +O=C(c1ccnc2ccccc12)N1CCC(N2CCC(Oc3ccc(S(=O)(=O)c4ccc5c(c4)OCO5)cc3)CC2)CC1 +NCCCC(=O)Nc1nc2nn(CCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +CC1(Nc2ccc(C(=O)NO)cc2)CCN(c2ccc3ncccc3c2)C1=O +N=C(N)NCCCC(NC(=O)Cn1c(-c2ccccc2)c(Cl)nc(NCCc2ccccc2)c1=O)C(=O)c1nccs1 +CN(C)C(=O)n1nnc(CNC(=O)CCCCCCCc2ccccc2)n1 +COc1ccc(S(=O)(=O)N2c3ccc(Cl)cc3C(O)(c3ccccc3Cl)C2C(=O)N2CCCC2C(N)=O)cc1OC +Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1CCCCC1COC(C)(C(=O)O)OC1 +COc1ccc(C(NC(=O)CC2CCN(Cc3ccn(-c4ccc(C(F)(F)F)cc4)c3)CC2)c2ccc(F)cc2)cn1 +COc1cc(NS(C)(=O)=O)ccc1S(=O)(=O)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1Cl +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(OC(=O)c2ccc(C)cc2)c1 +COc1ncc(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)cn1 +CCc1cc(O)c(OC)c(C(=O)NCC2CCCN2CC)c1F +CC1(CNC(=O)c2ccc(C#Cc3cccc(F)c3)cn2)COC1 +CCc1cc(C)n(CC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)n1 +CN1CCC(NC(=O)Nc2cccc(C#N)c2)CC1c1nc2ccccc2[nH]1 +COc1cccc2ccc(COc3ccc(-c4nn(C)cc4-c4ccncc4)cc3)nc12 +Cc1cc(-c2ccccc2)cc(=O)n1CCC(C)(C(=O)NO)S(C)(=O)=O +Cc1cccc(NC(=O)NC2N=C(N3CCN(C)CC3)c3ccccc3N(C)C2=O)c1 +CCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc(B(O)O)cc1)c1ccccc1 +CCN(c1cc(C(F)(F)F)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +Cc1ccc(C2=C(C(=O)Nc3nn[nH]n3)C(=O)NC(c3ccc(C4=CCCC4)cc3)(C(F)(F)F)C2)cc1 +COc1cnc(C(=O)Nc2ccc(F)c(C3(C)CS(=O)(=O)C4(CCN(C)CC4)C(=N)N3)c2)cn1 +CC(C)c1csc(Nc2ncc(SCCn3ccnc3)cc2OCc2ccccc2)n1 +O=C1NCCN1c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +COc1ccc(-c2[nH]c(-c3cccs3)nc2CCNS(=O)(=O)N(C)C2CCN(Cc3ccc(Cl)c(Cl)c3)C2)cc1 +CC(C)Nc1nc2ccc(-c3[nH]cnc3-c3ccccc3)cc2s1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)CCC(F)(F)F +CCN(C(=O)OCC(=O)Nc1ccc(-c2ccc(CC(=O)O)cc2)cc1Cl)c1ccc(C(C)(C)C)cc1Cl +O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccc(F)cc1 +CN(C)c1ccc(O)c(C(=O)c2ccc(C(=O)NC3CCCNCC3NC(=O)c3ccncc3)cc2)c1 +COc1ccc(N(Cc2cccc(C#N)n2)C2CCN(C(C)CCNC(=O)c3c(C)cc(F)nc3C)CC2)cc1 +CCOC(=O)c1c(CSc2ccccc2Cl)[nH]c2c1cc(O)c1ccccc12 +Cn1cc(-c2ccc3nc(NC(=O)c4ccccc4)c(Cl)n3n2)c(-c2ccc(F)cc2)n1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2cccc3ccccc23)[nH]c1=O +CC1CN(Cc2ccc(C=Cc3n[nH]c4cc(C5CC56C(=O)Nc5ccccc56)ccc34)cc2)CC(C)O1 +NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1ccc2cn[nH]c2c1 +Cn1cc(C(=O)N2CCC(NC(c3ccc(C(F)(F)F)cc3)c3cccnc3)CC2)c(C(F)(F)F)n1 +Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2ncccc2F)s1 +CCC(C1=C(O)OC(CC(C)C)(CC(C)C)CC1=O)c1cccc(NS(=O)(=O)c2cn(C)cn2)c1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cn(Cc4ccccc4)nn3)c(C(=O)O)n1)CC2 +CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)Nc2onc(C)c2C)c(COCCF)c1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(Cc3ccc(Br)cc3)CC2)CC1 +CC1CCN(C(c2ccc(C(F)(F)F)cc2)c2ccc(C(C)C(=O)O)cc2-c2ccc(C(F)(F)F)cc2)CC1 +CCc1nc(Nc2ccc(-c3cnco3)c(OC)c2)oc1-c1ccccc1 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+O=C1C(N2CC2)=CC(=O)c2c(OS(=O)(=O)c3cccc4cccnc34)cccc21 +Cn1nccc1-c1cc(NC(=O)Nc2ccccc2Cl)ccc1OCCN1CCCCC1 +COc1ccc(Cl)cc1S(=O)(=O)Nc1cc(C(=O)Nc2ccc(C(=O)O)cc2)cn(C)c1=O +CCCCCCCCCCCCn1c(N)c(N)c(=O)n(C)c1=O +CCC(=O)NCCn1c(C(=O)OC)cc2ccc(OC)cc21 +COC(=O)N1C2CCC1CC(O)(C#Cc1cccc(C)n1)C2 +O=C(CCCNC1C(O)C(O)C(O)C(O)C1O)NC12CC3CC(CC(C3)C1)C2 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)c2cc1OCCOC +O=C(c1cccc(F)c1Br)N1CC2CC(Oc3ccc(C(F)(F)F)cn3)C1C2 +CN(CCN1CCOCC1)c1ccc2c(n1)sc1nc(-c3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)cn12 +O=C(NC(c1cccnc1)C(F)(F)F)c1cc(OCc2ccc(F)cc2)c(Cl)cn1 +Cc1ccc(CCN2C3=NCC(Cc4ccc(O)cc4)N3CC2CCCNC(=O)C2CCC2)cc1 +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4ccc(Cl)nc4)c3)ncnc12 +O=C(NCC(=O)N1CCCC1B(O)O)c1c(Cl)cccc1Cl +O=C1C(N2CCC(c3ccc(O)cc3)C(F)(F)C2)CCN1Cc1ccc(F)c(Cl)c1 +Cn1cnc2ccc(-c3c(-c4ccccn4)nn4c3CCC4)cc21 +N=C(N)c1ccc(-c2ccc3cc(-c4cc(C(=N)N)ccn4)[nH]c3c2)cc1 +CCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +N=C(N)N1CCCC(NC(=O)CN2CCCCC(N3C(=O)c4ccccc4CS3(=O)=O)C2=O)C1O +O=C1NCC(c2ccc(F)cc2)C12CCN(C1(c3ccc(F)cc3)CCCCC1)CC2 +NC(=O)C=Cc1ccc(Oc2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cc1 +O=C(Cn1nc(C2CCCCC2)cc(Cc2ccco2)c1=O)NCCc1cccc(F)c1 +COCC(NC(=O)N1CC(=O)Nc2cc(Cl)cnc21)c1ccc(OC(F)(F)F)cc1 +CNC1CCc2c(c3ccccc3n2S(=O)(=O)c2cccc(C(F)(F)F)c2)C1 +Cc1cc(-c2n[nH]c3cc(NC(=O)N(C)Cc4cccnc4)ncc23)ccn1 +CC(CCN1CCN(c2ccc(F)cc2)CC1)NS(=O)(=O)c1ccc2ccccc2c1 +O=C(Nc1ccc2cc[nH]c2c1)c1c[nH]c2ccccc2c1=O +CC(C)Oc1ccc(-c2onc3c2CCc2cc(CNCCC(=O)O)ccc2-3)cc1C#N +Cc1nocc1C(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CCOc1ccccc1N1CCN(CCCn2ncc(N3CCN(CCOc4ccccc4OC)CC3)c(Cl)c2=O)CC1 +CCCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(C(=O)O)c(N)nc3ccccc23)cc1 +CSc1ccc(-n2c(-c3ccc(S(C)(=O)=O)cc3)cc(CC(=O)OCCCCO)c2C)cc1 +CC(C)N1CCC(N(C)C(=O)c2ccc(Cn3cnc4ccccc43)cc2)C1 +Nc1nc(NCC2CCCN2Cc2c(F)cc(F)cc2F)nc2nc(-c3ccco3)nn12 +Cc1cc(C)n(CCNCc2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)n1 +C=CC(=O)Nc1cc(Cl)ccc1C1CCNc2c(C(N)=O)c(-c3ccc(OCC4CC4)cc3)nn21 +CCCn1c(Nc2cccc(C(F)(F)F)c2)nc2nc(C3CCCC3)[nH]c2c1=O +Cc1nn(-c2ccccc2)c2c1C(c1ccc(O)c(O)c1)N1C(=N2)C(Nc2ccccc2)=Nc2ccccc21 +O=C(CSc1ccc(F)cc1)NC(Cc1c[nH]cn1)C(=O)NCCc1ccccc1 +Cc1ccc(CC(=O)Nc2ccc(NC(=O)C=Cc3ccc(-c4ccc5ccccc5c4)o3)cc2C(=O)c2ccccc2)cc1 +N#Cc1ccc(NC(=O)C(CN2CC(O)C2)Oc2ncnc3c2cnn3-c2c(Cl)cccc2C#N)nc1 +CCOc1cc(CN2CCCC(NC(=O)c3cncc(C)c3)CC2)ccc1C +CNC(=O)c1cnc(NCCc2ccc(O)cc2)nc1Nc1cccc(C)c1 +Cc1cc(SC2=C(O)OC(CCc3ccc(O)cc3)(C(C)C)CC2=O)c(C(C)(C)C)cc1NC(=O)c1cccnc1 +O=C(Nc1ccc(CCc2ccc(O)c(O)c2)cc1)c1ccc(Cl)cc1O +CC(=O)N(C)Cc1ccc(CN2CCN(c3ccccc3OC(C)C)CC2)n1C +O=C(c1ccc(Br)s1)C1CCN(C2Cc3ccccc3CC2O)CC1 +CC(C)(C)c1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(=O)(O)OCC(N)C(=O)O)c2)cc1 +N#Cc1ccnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4ccnc(N)c34)c(F)c2)c1 +Cc1cccc(C(=O)N2CC(C)OCC2Cc2cccc(-n3nccn3)c2)c1-n1nccn1 +CS(=O)(=O)N1CCc2oc(-c3ccnc(Nc4ccc(OCCN5CCCC5)cc4)n3)cc2C1 +CN(C)C1CCC(n2cc(C(N)=O)c(Nc3ccc(Cl)cc3)n2)C(C#N)C1 +O=C(O)c1cc(-c2ccc(OC3CCCCC3)c(Cl)c2)ncn1 +c1ccc2c[n+](CCCCCCCCCC[n+]3ccc4ccccc4c3)ccc2c1 +O=C(NCc1cccnc1)C1CN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CCN1C(=O)NC1CCCCC1 +Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OC(F)(F)C(F)F)c1 +Cc1onc(C(=O)N2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)c1[N+](=O)[O-] +O=S(=O)(CC1CC1)NCCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N1CCC1)CC2 +COc1cc(C)c2c(c1)C(c1ccc(O)cc1)(c1ccc(O)cc1)C(=O)N2 +Oc1ccc2c3c1OC1C(OCc4ccc(-c5ccccc5)cc4)CCC4(O)C(C2)N(CC2CC2)CCC314 +CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]c(=NC(=O)c1cscn1)n2CCC(N)=O +OCc1cccc(-c2nc(N3CCOCC3)c3cc[nH]c3n2)c1 +CCCn1c2ccc(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +CC(OC1CN2C(=O)C(O)CC2C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +NC(=O)c1cc(N2CCNCC2CO)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +CCCCOP(=O)(CCCCC1(C(=O)NCc2ccccn2)c2ccccc2-c2ccccc21)OCCCC +Oc1ccc(Cn2cnc3ncc(-c4ccc(F)cc4)nc32)cc1 +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccc(C(F)(F)C(F)(F)F)cc4)O2)C3=O)cn1 +COC(=O)c1cccc(CC2=C(c3ccc4c(c3)OCO4)C(=O)OC2(O)c2ccc(OC)cc2)c1 +CCn1cc(-c2ccnc3[nH]c(-c4ccc(CN5CCCC5)cc4)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1 +COc1ccc(C2CCN(CCCCc3ccccc3)CC2)cc1 +Oc1ccc2cc(-c3nc4ccc(O)cc4o3)ccc2c1 +O=C(O)c1ccc(-c2n[nH]c3c2Cc2cc(CN4CCOCC4)ccc2-3)cc1 +CCOc1cc(C(=CC#N)c2ccc(OC)c(O)c2)ccc1OC +COc1c(C(=O)NCCN2CCN(c3ccc(Cl)cc3Cl)CC2)cc(Br)c2ccccc12 +C=CC(=O)NCc1coc(-c2c(N)ncnc2Nc2ccc(Oc3ccc(F)cc3)c(Cl)c2)n1 +CC(C)c1ccc(-n2c3ccccc3n3c(CN(CC4CC4)CC4CC4)c(C(F)(F)F)nc23)c(Br)c1 +Cc1cc(C=C2C(=O)Nc3ncc(F)cc32)c2ccccc(OCCCN3CCOCC3)c1-2 +CC(=O)N1N=C(c2ccc(C)cc2)CC1c1c(C)nn(-c2ccc(S(N)(=O)=O)cc2)c1Cl +CNC(=O)N1CCC(NC(=O)Nc2nc(C)c(C(C)=O)s2)C(CN2CCCC(Cc3ccc(F)cc3)C2)C1 +O=C(Nc1ccccc1Cl)c1ccc(-c2cc3scnc3cc2Cl)s1 +CC(NC(=O)c1ccc(C#Cc2cccc(F)c2)nn1)C(C)(C)O +Cc1cc(C(=O)N(CC2CC2)CC2CCCO2)ccc1-c1ccccc1 +O=C(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)C1CC(Cl)C1 +N=C(N)c1cccc(C2=NOC(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)C2)c1 +FC(F)n1c2ccccc2c2cc(CCOc3ncccc3-c3cncnc3)cnc21 +COc1ccc(CC(=O)NCC2CCCN(Cc3ccc(SC)cc3)C2)cc1 +COc1cc(CNC(=S)NC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)cc(Cl)c1O +COCC(C)Oc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C)n1 +O=C(NC1C[N+]2(CCCOc3ccccc3)CCC1CC2)C(c1cccs1)c1cccs1 +CC(C)(Cc1ccc2ccccc2c1)NCC(O)COC(c1ccccc1)c1ccccc1 +COc1ccc(C(=O)NCCCCN2CCc3ccc([N+](=O)[O-])cc3C2)c(OC)c1OC +Cc1cc(C)c(Nc2nc3ccccc3n3cncc23)c(Cl)c1 +Cn1c(=O)c2[nH]c(-c3cccc(OCCN4CCCCC4)c3)nc2n(C)c1=O +CC(C)CN1CCC(CNC(=O)c2cc(Cl)cc3[nH]cnc23)CC1 +CN1CCN(Cc2cc3c(nc2C=O)N(C(=O)Nc2cc(NC45CC(C4)C5)c(C#N)cn2)CCC3)C(=O)C1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1CCCS(N)(=O)=O +O=C(CO)NC(CNc1cc(-c2ccncc2)c(-c2cccc3ccccc23)nn1)Cc1ccccc1 +Cc1cccnc1CNC(=O)c1cc(-c2ccccc2)nc(N)n1 +O=[N+]([O-])c1c(Nc2cc(F)cc(C(F)(F)F)c2)ccc2nonc12 +COCCc1sc[n+](CCCCc2ccc(CCCC[n+]3csc(CCOC)c3C)c3ccccc23)c1C +COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cc3cccnc3SC)cc(OC)c21 +OCC1OC(c2cc(Cc3ncc(-c4ccoc4)s3)c(Cl)cc2Cl)C(O)C(O)C1O +N#Cc1cc2c(cc1Cc1cccc(Cl)c1Cl)c(=O)c(C(=O)O)cn2CCO +CN=C1NC(=O)C(=Cc2c[nH]c3ccc(Br)cc23)N1C +N#Cc1ccc(OC(c2ccccc2)C2CCNCC2)cc1Cl 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+CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cc(Cn3c(=O)[nH]c(=O)c4ccccc43)cnc2Cl)C1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(N3CCOC(CO)C3)c2c1=O +O=[N+]([O-])c1cc2nc(C(F)(F)F)[nH]c2cc1[N+](=O)[O-] +CN(Cc1ccc(F)cc1)C(=O)Cc1nc(S(=O)(=O)Cc2ccccc2)c2ccccn12 +COc1ccc(-n2[nH]c3c(cnc4cc(OC)ccc43)c2=O)cc1 +CCCC(Cc1ccc(OC)c(C(=O)NCc2ccc(C(F)(F)F)cc2)c1)C(=O)O +O=C(c1ccccc1-n1cccn1)N1C2CCC1C(COc1ccc(F)cn1)C2 +COc1cc2c(cc1CNC1CCCNC1c1ccccc1)C(C(F)(F)F)OC2 +O=c1c(-c2ccccc2)c[nH]c2c(-c3cccc(C(F)(F)F)c3)cnn12 +Cc1cc(SC2=C(O)OC(CCc3ccccc3)(C(C)C)CC2=O)c(C(C)(C)C)cc1OS(=O)(=O)c1cccnc1 +CC(C)CC(=O)OCC(CO)OC(=O)CC(C(C)C)C(C)C +CC1CCCN1C1CCN(c2ccc(N3CCC4(CCN(S(=O)(=O)c5ccccc5)CC4)C3=O)cc2)CC1 +O=C(OCC1CCc2ccccc2N1S(=O)(=O)c1ccc(Cl)cc1)N1CCC(N2CCCC2)CC1 +COc1nc(N2CC3C(=O)N(C)C(N)=NC3(c3ccc(F)cc3F)C2)nc(C2CC2)c1F +C(#Cc1ncnc2scc(-c3ccccc3)c12)COCCN1CCCC1 +COc1cc(CC2COCC2Cc2ccc3c(c2)OCO3)cc(OC)c1OC +O=C(c1cc[n+]([O-])cc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +COc1cccc(-c2n[nH]c(Cc3cccc(Br)c3)n2)c1 +C#CCN1CC(NC(=O)c2ccc(Cn3c(C(C)(C)C)nc4ccccc43)cc2)C(C(=O)NO)C1 +N#CC1(NC(=O)C2CCCCC2C(=O)N2CCN(c3nc4c(s3)COCC4)CC2)CC1 +CCN(CC)C(=O)C1CCC2C3CC=C4N(N)C(=O)CCC4(C)C3CCC12C +O=C(O)C1CCN(C(=O)C=Cc2ccc(Sc3ccc4c(c3)OCCO4)c3ccccc23)CC1 +CC(=O)N1CCN(Cc2cn3cc(-c4cccc(O)c4)nc(N4CCOCC4)c3n2)CC1 +C=C(C)c1cccc(C(C)(C)NC(=O)N(C)c2ccc(Cl)cc2)c1 +CN1CCN(CCCN(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)C2CCC3(c4nccs4)CC23)CC1 +O=C(c1ccc(O)cc1O)N(Cc1ccccc1)c1ccc(-c2ccccc2Cl)cc1 +O=C(NCc1cc2ccccc2[nH]1)N1CCc2cnc(NC3CCOCC3)nc2C1 +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3ccnn3C)nc12 +O=C(O)c1cccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOCC4)N3)n2)c1 +COc1ccc(C2(Cc3ccccc3)CCN(C(=O)OC(C)(C)C)C2=O)cc1OC1CCCC1 +CN(C(=O)CSc1nc(-c2ccccc2)cn1N)C(c1ccccc1)c1ccccc1 +Clc1ccc(OCCNCc2cccs2)c2c(Cl)c[nH]c12 +COc1ccc(CS(=O)(=O)C=Cc2c(OC)cccc2OC)cc1N +O=c1n(Cc2cnn(-c3ccccc3Cl)c2)nc(-c2ccc(Cl)cc2)n1CC(O)C(F)(F)F +COC(=O)C=Cc1oc(=O)c(COC(C)=O)c(OC)c1CO +Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(CC(C)C)nc2)n1 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+CC(C)S(=O)(=O)NC1Cc2ccc(Cn3cc(CO)c(C(F)(F)F)n3)cc2C1 +Cc1nc(C#Cc2ccc(-c3ccc(F)c(F)c3)nc2)cs1 +O=C(Nc1ccccc1)N1CCN(Cc2cccc(S(=O)(=O)c3ccc(Cl)cc3)c2)CC1 +COc1ccc(S(=O)(=O)NCc2ccc(-c3ccc(CN(C)CCO)cc3)cc2)cc1 +N=C(N)c1ccc2cc(-c3cccc(OCCCOc4ccccc4)c3)oc2c1 +CCCCN(C(=O)c1ccccc1Cl)c1nnc(-c2cc(C)c(CN3CC(C(=O)O)C3)c(C)c2)s1 +CNC(=O)c1ccc(Nc2nc3ccc(C(=O)N(CCC(C)C)CCC(C)C)cc3n2CCCN2CCCCC2)cc1 +CN(CC(=O)Nc1ccc(S(=O)(=O)N=c2sc(S(N)(=O)=O)nn2C)cc1)C(=N)N +CCOc1c(Br)cc(OC)cc1CNCCCNc1nc(O)c2ccccc2n1 +COc1ccc(C=C(C)C(O)c2cc(OC)c(OC)c(OC)c2)cc1O +CCC(O)(C(=O)Nc1nnc(CCCCc2nnc(NC(=O)C(O)(CC)c3ccccc3)s2)s1)c1ccccc1 +CC(=O)NC1CCN(c2ncnc(C)c2C#Cc2ccc(N)nc2)CC1 +COc1cc(C(=O)NCC(C)(C)CN(C)C)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +CNc1nnc(-c2ccc3[nH]cc(-c4cnc5ccccc5c4)c3c2)s1 +CCCCNCc1ccc2n1-c1ccccc1SC2c1ccc(OC)cc1OC +CS(=O)(=O)c1cccc(-c2cc3c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)ncnc3s2)c1 +O=C(CC(Cc1ccc(Br)cc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)C(S)Cc1ccccc1 +O=C(O)Cc1csc(=NC(=O)CS(=O)(=O)c2ccc(-c3ccccc3)cc2)n1O +O=C(Nc1ccc(C2CCNC2)cc1)Nc1ccc(Cl)nc1 +CN(C)CC(NC1CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1)c1ccccc1 +CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(NCC(C)O)c2c1Cl +CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(F)cc12 +COc1ccc(CN2CCN(CCCOc3ccc(C(=O)NC(=N)N)cc3NC(=O)c3ccccc3)CC2)c(OC)c1OC +Oc1ccc2c(c1O)-c1cccc3c1C(C2)N(CCCl)CC3 +COc1ccc(-n2ncc3c(NCC(C)NS(=O)(=O)c4c(C)cc(C)cc4C)cc(C)cc32)cc1 +COc1ccccc1N1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1 +CS(=O)(=O)N1CCc2c(c(-c3ccc(Cl)c(Cl)c3)nn2CCCN2CCC(n3c(O)nc4ccccc43)CC2)C1 +O=C(OC1CCCC1Cc1ccc(O)cc1)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1 +CCOC1CCc2nc3cc(Cl)ccc3c(NCCCCCCCCCNc3c4c(nc5cc(Cl)ccc35)CCC(OCC)C4)c2C1 +N#Cc1ccc(CNC(=O)C2COc3ncccc32)c(Cl)c1 +O=C(Nc1ccccc1Cl)N1CCN(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CN(CCOCCNC(=S)NC(=O)c1ccc(Cl)c(Cl)c1)Cc1ccccc1 +CC1Cn2c(nnc2C(F)(F)F)CN1C(=O)c1cccc(C(F)(F)c2n[nH]c(=O)c3c2CCCC3)c1 +COc1ccc(N2C(=O)c3c(Cl)ccc(NS(=O)(=O)c4ccc(C(C)(C)C)cc4)c3C2=O)c(OC)n1 +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1Cc1nnco1 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+Cc1cncc(-c2cc3c(cn2)cnn3-c2ccc(C(F)(F)F)c(N3CCCC(N)C3)n2)n1 +COc1ccc(C=CC(=O)NCCCCCNc2ccnc3cc(Cl)ccc23)cc1 +CC(C)N1CCN(C(CN2CCN(CCCc3ccc(-c4ccccc4)cc3)CC2)c2ccc(F)cc2)CC1 +COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC=Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1 +COCC1(OC)c2ccccc2-c2ccc(C(=O)N=C(N)N)cc21 +Cc1cc(C)nc(N2CC3CN(C(=O)c4cccc5c4OCCCO5)CC3C2)n1 +O=C(O)c1cccc(S(=O)(=O)NCCc2ccccc2F)c1 +O=S(=O)(c1ccccc1)c1cn(C2CCNC2)c2ccccc12 +Cc1ccccc1Cc1ccc(N2CC(C)CC2CC(=O)O)cc1 +Cc1cccc(C)c1OCC(=O)NC(Cc1ccccc1)C(O)CN(CC(C)C)S(=O)(=O)c1ccc(N)cc1 +Cc1nc(N)cc(OCC(=O)C(C)(C)C)c1CNC(=O)c1cn(Cc2ccccc2)nn1 +COc1ccc(S(=O)(=O)N(CC2COC(=O)N2)CC(O)C(Cc2ccccc2)NC(=O)OC2COC3OCCC23)cc1 +CCN(CC)Cc1ccc(C(c2ccccc2Cl)n2cncn2)cc1 +CC(C)C(NC(=O)c1ccc(N=Nc2ccccc2)cc1)C(=O)NC(C=O)Cc1ccccc1 +O=C(Nc1ccnc(NC(=O)C2CC2)c1)c1c(Cl)cc(CO)cc1Cl +CCC(CC)(Cc1nc2c(F)cc(OCc3ccc(C)cn3)cc2n1Cc1ccc(OC(F)(F)F)cc1)C(=O)O +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2Cc3cn[nH]c3C2)c(-c2cncnc2)c1 +O=C1C(c2ccccc2)=[N+]([O-])c2cc([N+](=O)[O-])c(C=C(Cl)c3ccccc3)cc21 +N=C(N)NCCCC1C(=O)N(C(=O)c2cccs2)C1C(=O)O +CC(=O)N1N=C(c2cc(F)ccc2F)SC12c1cc(F)cc(F)c1OCC2CCN +CC(NC(=O)c1c[nH]nc1C(F)(F)F)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CCOC(=O)C1CCCN(C(=O)C(Cc2ccccc2)NC(=O)Nc2ccc(Br)cc2)C1 +O=C(NCc1ccc(-c2nccs2)cc1)C(O)C(O)C(=O)N1CCCC1c1cccc(Cl)c1 +CC(C)(C)NC(=O)C1CCN(Cc2cc(Br)cc(NC(=O)c3cccc(C(F)(F)F)n3)c2)CC1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1ccc(-c2ncc(C(F)(F)C(F)(F)F)[nH]2)c(Cl)c1 +CNC(=O)c1ccc(Nc2nc(OCCO)c3c(-c4ccc5nc(C)oc5c4)c[nH]c3n2)c(OC)c1 +O=C(c1ccc(Oc2nccnc2N2CCOCC2)cc1)c1nc2ccccc2s1 +Oc1ccc(-n2c(-c3ccccc3)nc3ccccc32)cc1 +COc1cccc(CN2CCC(CCCC(=O)c3ncco3)CC2)c1 +NS(=O)(=O)c1ccc(CCNc2nc(Oc3ccccc3)nc(Oc3ccccc3)n2)cc1 +CCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC(C)CCC(C)=O)S(=O)(=O)c1ccc(OC)cc1 +Cc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C#N)CC3)n2)ccc1F +COc1cc(Nc2c(C#N)cnc3cc4cc(OCCN5CCOCC5)c(OC)cc4cc23)c(C)cc1Cl +CCCCCCOc1ccc(C=CC(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +N#Cc1ccc(-c2cc(C(=O)O)nn2-c2ccc(Cl)c(Cl)c2)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCOCC2)c(-c2ccc(CO)nc2)c1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(OCC(=O)OCC4CCCO4)cc3)ncc2Cl)c1 +COCc1ccccc1C(=O)N(CCc1ccc(Cl)cc1)C1CCC2(CC1)OCCO2 +c1ccc2c(c1)CN(CCCCc1nc3ccccc3s1)C2 +COc1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nc2c(C(C)C)cccc12 +N=C(N)c1ccc(COc2ccc3c(c2)CCC(CC(=O)O)C3=O)cc1 +COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1cc2[nH]c(-c3ccco3)c(C3CCCCC3)c(=O)n2n1 +CCOc1ccc(CNC(=O)n2sc3ncccc3c2=O)cc1OC +COC(C(O)CO)C1OC(C(=O)O)=CC(NC(=N)N)C1NC(C)=O +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(-c2cncnc2)c1 +C=C(c1ccccc1)C12CCCC1CC(CCCCCC)=C2c1ccccc1 +O=C(Nc1ccc(F)c(-c2nc3ncccc3o2)c1)c1cscn1 +CC(NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1 +Fc1cc(-c2ccccc2)cn2c(Cc3ccc4ncccc4c3)nnc12 +CCCCCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4c5ccccc5CC4N(C)C)ncc23)ccn1 +COc1nn2cc(-c3cc4cc([N+](=O)[O-])ccc4o3)nc2s1 +CS(=O)(=O)CCCn1c(CN2C(=O)C(=NOCCF)c3cccnc32)nc2ccccc21 +CN(C)CCCc1ccc(OC(F)(F)F)c(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1c(-c2cccs2)nc2sccn12 +OC1C(O)C(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C2CC12 +CCC1(CC(=O)O)CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(CNS(=O)(=O)C2CCC2)C2CC2)C1=O +O=C1OC2(CCC(C(=O)Nc3ncc(-c4ccccc4F)cn3)CC2)c2ccncc21 +Cn1c2c(c3ccccc31)C(=O)c1c[n+]([O-])c3ccccc3c1C2=O +Cn1c(=O)c2c(cc(C=Cc3ccc(F)cc3)n2C)n(C)c1=O +COc1ccc2cc3cc(C(=O)N4CCN(C5CCCCC5)CC4)oc3nc2c1 +CC1CN(c2ccc(C(F)(F)F)c(-c3cnc(N)c(C(=O)Nc4ncccc4N4CCC(C)(N)CC4)n3)n2)CCO1 +CC(C)(NC(=O)OCc1ccccc1)C(=O)N1CCc2c([nH]c3cccc4c(=O)[nH]nc2c34)C1 +COC(=O)CNC(=O)C1(c2ccc(-c3ccc(CCN4CCCC4C)cc3)cc2)CCCC1 +CNCCN1CCC(c2cc(C)c3[nH]c(-c4ccc(F)cc4OC)nc3c2)CC1 +CCOCCCOc1ccc(S(=O)(=O)N2Cc3cc(O)c(O)cc3CC2C(=O)NO)cc1 +Cc1cc(NN=Cc2ccc(OC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)c2c(Cl)ccc(C)c2n1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CS(=O)(=O)C(c2ccccc2)c2ccccc2)CC1 +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2c(c1)NCC(CN1CCC(O)C1)O2 +COc1ccc(C=CC(=O)SSC(=O)C=Cc2ccc(OC)cc2)cc1 +O=C(Nc1ccc(CO)cc1)c1cnn2c(-c3ccccc3)ccnc12 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+CCOC(=O)Nc1cc2c(cn1)NC(c1ccccc1)C(C)N2 +O=C(Nc1ccc(-c2ccccc2)cc1)c1ccccc1Cn1ccc2ncnc-2c1 +COc1cc2ncnc(Oc3cc(NC(=O)Nc4cc(C(C)(C)C)on4)ccc3F)c2cc1OC +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(Br)cn1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCCOCC4)cc3OC)ncc2C(F)(F)F)c1 +O=c1c(N2CCC(O)CC2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 +CN1C(=N)NC(C)(c2sc(-c3cccc(-c4nnco4)c3F)cc2Cl)CS1(=O)=O +Cc1c(C(=O)NCCN2CCN(c3cccc(Cl)c3Cl)CC2)cc(-c2ccccc2)n1C +Cn1c(=O)c2nc(C3CCCCC3)[nH]c2n(C)c1=O +COc1cc(OC)c(C(=O)C=Cc2cnccn2)c(OC)c1 +O=C(CCc1c(C(=O)O)[nH]c2ccccc12)Nc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 +O=C(C1CCCN(c2ccc3nc(C4(Cc5ccccc5)CC4)[nH]c3n2)C1)N1CCCC1 +O=C(Nc1cccc(CN2CCC(C(=O)NC(CO)C3CCCCC3)CC2)c1)c1cccc(C(F)(F)F)n1 +CN1C(=O)c2cccnc2N(C2CC2)c2cc(Cl)cnc21 +O=C1Nc2ccc(C(=O)CCl)cc2C1=Cc1cnc[nH]1 +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C12CN(Cc1cc(C(=O)O)cs1)CC2c1ccc(C#N)cc1 +O=C(Nc1cccnc1)c1cccc(Oc2ccc3c(c2)c(=O)ncn3Cc2c(F)cc(F)cc2F)c1C(F)(F)F +CC(C)c1noc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)n1 +CCS(=O)(=O)c1ccc2c(c1)nc(C1CC1)n2CC1CCOCC1 +COCC1OC(O)(C(=O)C(=O)N2CCCCC2C(=O)OCC(C)=CC2CCC(O)C(OC)C2)C(C)CC1OC +Cc1ccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CCN(CC4CCOCC4)CC2C)C3(C)C)nc1 +N#Cc1ccc(Cn2cncc2COCc2ccc(C#N)cc2-c2cccc(OC(F)(F)F)c2)cc1 +O=C1C=C(N2CC2)C(=O)C(c2ccc(Oc3ccccc3)cc2)=C1N1CC1 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3C(=O)N(C)CCO)cc2)cs1 +CC(C)C(CC(O)C(N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NC12CC3CC(CC(O)(C3)C1)C2 +COc1ccc(CCNc2cc(-c3cccc(S(N)(=O)=O)c3)nc(OC)n2)cc1 +CC1(C)CN(C(=O)Cn2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cc3c(Oc4cccnc4)ccnc32)C1 +N=C(N)c1cccc(-c2[nH]c(O)nc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +CCN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 +CC(=O)c1ccc(-c2nccnc2OC2CC(Nc3nc4ccccc4s3)C2)cn1 +COc1cc(NS(=O)(=O)c2ccc(Cl)cc2)ccc1-c1cncnc1C +CSC(=S)N1CC2(CCCCC2)COC1=Nc1cc(C(C)(C)C)no1 +CNc1nc(Nc2cc(OC)c(C(=O)N3CCC(F)(F)CC3)cc2Cl)ncc1Cl +[H]C([H])([H])C(c1ccccc1-c1ncc(C)c(NCc2ccc(-n3ccnn3)cc2)n1)C([H])([H])[H] +CCOC(=O)c1cc2ccc(Oc3ccnc(C(=O)NC)c3)cc2s1 +Nc1ccc2c(Nc3ccc(CN4CCCCC4)cc3)c3ccc(N)cc3nc2c1 +FC(F)(F)Oc1cccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCN1CCS(=O)(=O)CC1 +O=S(=O)(c1cccc(C(F)(F)F)c1)c1cc(Cl)c2oc3c(c2c1)CNCC3 +Clc1ccc2[nH]c3c(c2c1)CCN(CCc1ccncc1)C3 +CCC(=O)N(CCCCCCCNC(=N)N)C1CCN(CCc2ccccc2)CC1 +COc1ccc(C2c3[nH]c4ccccc4c3CC3C(=O)N(C4CCCCC4)C(=O)N32)cc1 +Cc1ccc(N2CCN(C(=O)C(C)Cc3ccc(Cl)cc3)CC2)c(C(CC(C)C)NC(=O)CCN(C)C)c1 +CCOc1ccc(-n2c(C)c3c(C)nnc(NCc4cccc5cccnc45)c3c2C)cc1 +CN1CCCC(c2nc3ccccc3n2CCOc2ccccc2)C1 +Clc1ccc(-c2c[nH]c3ncc(-c4ccncc4)nc23)cn1 +CC(=O)c1ccc(-c2ccc(-c3csc(C(=O)NCCN4CCOCC4)c3)cc2)cc1 +O=C(NCC1CN(c2ccc3c(c2)OCc2nccn2-3)C(=O)O1)c1ccc(Cl)s1 +CCCCCCCCCCNC(=S)N1C(CO)C(O)C(O)C1CO +C=CCNc1nc(C#CCO)cn2c(-c3ccc(-c4cnc(C5CC5)[nH]4)cc3)cnc12 +COC(C)(C)CCn1nc(Nc2c(C)cccc2C)c2cnc(Nc3ccc(N4CCNCC4)cc3)nc21 +COC(=O)c1c(O)cccc1OCC=Cc1cccc(-c2onc(C(=O)O)c2CO)c1 +Cc1c(-c2cccc(O)c2)n(Cc2ccc(OCCN3CCCCC3)cc2)c2ccc(O)cc12 +COc1ccc2[nH]nc(-c3cc(N4CC5CCC(C4)O5)ncn3)c2c1 +COc1ccccc1N1CCN(CCn2c(=O)[nH]c3[nH]c(-c4ccccc4)cc3c2=O)CC1 +O=C(CN1CCC(C(=O)c2ccc(OCCC3CC3)cc2)CC1)NCc1nc2c(c(=O)[nH]1)COCC2 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cc2ccccc2[nH]1 +COc1cc(OC(C)c2ccccc2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +COc1cc2cc(-c3cc(F)c(OC)c(F)c3)cnc2cc1OC +O=S(=O)(c1ccccc1)c1cc(Nc2cc(-c3ccc(C(F)(F)F)cc3)[nH]n2)nc(NC2CCC(O)CC2)c1 +Cc1ccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1 +O=c1[nH]c(N2CCC3(CCN(c4ccc(Cl)cc4)C3)C2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +Cc1cc(NC(=O)C(=O)c2cn(Cc3ccno3)c3ccccc23)sn1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])C(=O)Nc1cccc(Cl)c1 +O=C(NCCCCN1CCCC1)C1C(C(=O)NCc2c(F)cc(F)cc2F)C2C=CC1C21CC1 +CCCc1c(CCN(C)C)c2cc(OC)ccc2n1S(=O)(=O)c1ccccc1 +Cc1cccc2cc(C(C)Nc3nc(N)ncc3F)n(-c3ccccc3)c(=O)c12 +CC(=O)NCCNS(=O)(=O)c1ccc(-c2sc(NC(C)=O)nc2C)o1 +CCN(CC)c1ccc(C(NC(=O)C=Cc2ccccc2)NC(=O)C=Cc2ccccc2)cc1 +O=C(OCC1C2CC3CCC1N3CC2=Cc1cccs1)c1ccc2ccccc2c1 +COc1ccccc1N1CCN(CC=CCNC(=O)c2cc3ccccc3o2)CC1 +O=C1NC(=O)c2ccc(-c3ccc(O)cc3)cc2C1=CNc1ccc(CN2CCCCC2)cc1 +CN(C(=O)c1cc(-c2ccccn2)n[nH]1)c1ccc(OCc2ccc3ccccc3n2)cc1 +O=c1n(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)nc2ccc(C(F)(F)F)cn12 +NC(=O)Nc1ccc(-c2cccc3onc(N)c23)cc1 +O=C(O)C1=C(NC(=O)C2(Cc3nc(-c4ccc(O)cn4)no3)CCC2)CCCC1 +Cc1nc2c([N+](=O)[O-])c(Cl)c(Cl)cc2n1Cc1ccc(-n2cccc2)cc1 +COc1cc(-c2ccc(Cl)cc2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ncc(F)cn3)ccc21 +Cc1cccc(N2CCN(CC(O)CNC(=O)c3nc(C(C)C)n(-c4ccccc4)c3C)CC2)c1C +CN(C)c1ccc(-c2cc(-c3ccc(N)cc3)[se+]c(-c3ccc(N)cc3)c2)cc1 +COCCOc1c(OC)cc2c(N)nc(N3CCN(C(=O)C=Cc4ccc(C#N)cc4)CC3)nc2c1F +NC1(c2ccc(-c3nc4nc(O)ccn4c3-c3ccccc3)cc2)CCC1 +Cn1cnc2c(C#N)nc(-c3ccc(OCc4ccccn4)c(C(F)(F)F)c3)cc21 +CN1CC(C(NC(=O)c2ccc3cnccc3c2)c2ccc(Cl)c(Cl)c2)C1 +CCOC(=O)c1ncn2c1CN(Cc1ccccc1)C(=O)c1c(Cl)cccc1-2 +O=C(NC(CS(=O)(=O)c1ccc(Sc2ccccc2)cc1)C(=O)NO)OCc1ccccc1 +CNC(=O)C(NC(=O)C(Sc1ccccc1F)C(O)C(O)C(Sc1ccccc1F)C(=O)NC(C(=O)NC)C(C)C)C(C)C +c1ccc(CN2CCN(CCCNCc3cccnc3)CC2)cc1 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCCC2CCOC2)cc1F +COc1ccc2c(CC(=O)O)nn(Cc3nc4ccccc4s3)c(=O)c2c1 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+CC(C)CN(NC(=O)c1cccc(-c2ccccc2)c1)c1nc(C#N)ncc1Br +N#Cc1c[nH]c(C(=O)Nc2ccc(C3(O)CCOCC3)cc2C2=CCCCC2)n1 +CC(=O)OC1(C)CCC2CC1OOC2(CS(=O)(=O)c1ccccc1)c1ccccc1 +O=c1[nH]c2ccccc2c2c(=O)n(-c3ccc(Cl)cc3)[nH]c12 +COc1ccccc1N1CCN(CCCC(=O)c2cccc3c(=O)c(C)c(-c4ccccc4)oc23)CC1 +Cc1cc(Cl)ccc1NC(=S)NNC(=S)Nc1ccc(F)cc1 +CNc1ncc2cc(-c3cc(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4C)ccc3C)ccc2n1 +COCCCCN1CCN(c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)C1=O +Nc1cccc(-c2nc(N3CCOCC3)c3cnn(-c4ccccc4)c3n2)n1 +Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(-n4nccn4)cc32)cn1 +O=C(C1CC1)N1CCN(C(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Cc1nn(Cc2ccc(-c3nc4ccncc4[nH]3)cc2F)c(C)c1CC(=O)O +CC(=O)NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCCc2cccc3ccccc23)C1=O +CCN(CC)CCn1nc2c3c(c(NCCNCCO)ccc31)C(=O)c1c(O)ccc(O)c1-2 +Cc1ccc(-c2ccc(C(=O)O)c(NS(=O)(=O)c3ccc(C(=O)N(C)C)cc3)c2)c2ccccc12 +Cc1cc(S(=O)(=O)NC(=N)NNc2ccc(S(N)(=O)=O)cc2)c(SCc2cc3c(cc2Cl)OCO3)cc1Cl +NC(N)=NC(=O)c1ccc2c(Cl)cnc(-c3c(F)cccc3F)c2c1 +COc1ccc(Cc2cc(C3OC(SO)C(O)C(O)C3O)c3c(c2Cl)CCCO3)cc1 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+Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccccc4)cc3s2)S(C)(=O)=O)o1 +COc1cc(OC)cc(N(CC#Cc2ncccc2OC)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +NC(=O)Nc1cc(-c2ccnn2-c2ccc(F)cc2Cl)ccn1 +N#Cc1c(Cl)cccc1OCC(O)CN1CCCC1Cc1ccccc1O +Cc1nc(NCCO)cc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)n1 +CS(=O)(=O)N1CCc2c(c(-c3ccc(Cl)c(C#Cc4cccs4)c3)nn2CCCN2CCOCC2)C1 +O=S(=O)(NCC1CC1)c1ccc(NN2CCCCC2)cc1C(F)(F)F +COC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2 +CN(C)c1cc[n+](CCCCCCCCCCCC[n+]2ccc(-n3cnc4cncnc43)cc2)cc1 +COCCNCc1ccc(C=Cc2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)nc1 +O=C1Cc2c([nH]c3ccccc23)-c2cc(I)ccc2N1 +CC#CCOc1cnc(C(=O)Nc2cccc(CNc3cccnc3N)c2)cn1 +CC1(C)CC(=O)c2ccc(OCc3cccc(Cl)c3)cc2O1 +Cc1cnc(Cl)nc1-c1ccc(N(Cc2ccc(CNC(=O)c3cccs3)cc2)C(=O)c2ccc(O)cc2O)cc1 +COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(Br)cc4)c(C)c3)c2cc1OC +O=C(OCCO)c1[nH]c2ccc(Cl)cc2c1C1(c2ccccc2)CC1 +COc1ccc2c(c1)C(=Cc1c[nH]cn1)C(=O)N2 +COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3cccc(C)c3)c2cc1OC +COc1ccc(CN2C(=O)CNC(c3ccccc3)(C(Oc3nc(C)cc(C)n3)C(=O)O)c3ccccc32)cc1 +O=C1NC(=O)C(Cc2ccc(N3CCC(NCC(O)c4cccc(Cl)c4)CC3)cc2)S1 +O=c1cc(C=Cc2ccc(O)c(O)c2)oc2cc(O)ccc12 +N#Cc1ccc(S(=O)(=O)N(Cc2ccc(-c3nnn[nH]3)cc2)Cc2ccccn2)cc1 +Cc1nc2c(s1)C(=O)C=C(Nc1ccc(Br)cc1)C2=O +CC1(C)CCC(C)(C)c2cc3c(cc21)OC1CCCCCC31c1ccc(C(=O)O)cc1 +CC(C)C(CC=C1CC(CO)(COC(=O)c2ccccc2O)OC1=O)C(C)C +Cc1c(CNCC(C)C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1CCCc2ccc(CC(C)C)cc21 +COc1ccc(-n2nnc(-c3ccccc3NC(=O)Nc3ccc([N+](=O)[O-])cc3)n2)cc1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(OCCC4CC4)cc3)C2)cc1 +CCC1(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CCNCC1 +CSc1sc(C(=N)N)cc1-c1nc(-c2ccc(Cl)c([N+](=O)[O-])c2)cs1 +O=C(O)CCc1ccc(OCCN(Cc2ccc(C(F)(F)F)cc2)c2nc3ccccc3s2)cc1 +Nc1nc2c(cnn2CCc2ccc(O)cc2)c2nc(-c3ccco3)nn12 +CC(C)CC1CC(C(O)CC(=O)Cc2ccccc2)C(=O)N1 +CC(C)(C)c1cc2cc[nH]c2cc1NC(=O)c1c[nH]c2ccccc2c1=O +CCCC[S+]([O-])c1cc2c(-c3ccccc3)nc(-c3ccccc3)nc2s1 +O=C(Nc1cccc(O)c1)c1ccc(OCCCN2CCCC2)cc1OCc1cccnc1 +NC1CCCCC1NC(=O)c1c2c(c3c4c(ncnc14)-c1ccccc1C3=O)NC1CCCCC1N2 +OC(CNCc1ccccc1OCCN1CCOCC1)c1cc(Br)cs1 +O=C(O)CCC(=O)Nc1nc2ccc(NC(=O)c3cc(Br)c(Br)[nH]3)cc2s1 +Cc1oc2c(c1CC(=O)Nc1nc(-c3cccc(C(F)(F)F)c3F)cs1)c(=O)n(C)c(=O)n2C +N#CC1CCCN1C(=O)CNC1CC2CC(OC(=O)Nc3ccccc3)CC2C1 +COc1cc(OC(C)c2ccncc2)c(F)cc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +NC(=O)C1CCCN(C(=O)c2cc(-c3ccc4[nH]ncc4c3)on2)C1 +CC(C)Oc1cc2c(-c3cc(N4CCN(C(=O)C5CC5)CC4)ncn3)n[nH]c2cc1F +CN1C2CCC1C(c1ncc(-c3ccccc3)o1)C(c1ccc(Cl)cc1)C2 +CC(c1ccc(F)cc1)N1C(=O)OC(Cc2ccccc2)(c2nc3cc(Cl)ccc3[nH]2)C1=O +O=C(NCC1CC1c1cccc2oc(CCCCc3ccccc3)cc12)C1CC1 +CN1CCN(Cc2ccc(NC(=O)CNc3ccc(-c4ccc(NC(=O)C5CC5)nc4)cc3F)cc2C(F)(F)F)CC1 +CN(CCCNc1ncnc2oc(-c3ccccc3)nc12)c1ccccc1 +FC(F)(F)c1cc(COCc2ccccc2-c2ccccc2)cc(C(F)(F)F)c1 +N#CC(C(=O)Nc1ccc(C(F)(F)F)cc1)=C(O)C1CC1 +Nc1ncnc2c1ncn2C1CCC(OCP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1 +Cc1ccc(Cl)cc1NC(=O)CCCNC(=O)C(C)c1ccc(CC(C)C)cc1 +CC1CCc2cc(C(=O)N(C)Cc3ccnc(Cl)c3)ccc2N1C(=O)c1ccc(O)cc1O +Cc1ccc(Nc2ncnc3sc(NC(=O)CCCCCC(=O)NO)cc23)cc1C +COc1ccc(-c2cc3nc(Br)ccc3c(NCCCN)n2)cc1 +Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccc2nc(-c3cccnc3)nn2c1 +Cc1nc(N)ncc1CNC(=O)Cn1c(C)cnc(NCCc2ccc3c(c2)CCO3)c1=O +CCOC(=O)c1ccccc1NC(=O)Cn1c(-c2nonc2N)nc2ccccc21 +COc1ccc(F)c(-c2ccc3c(NC(=O)c4ccc(N5CC(C)NC(C)C5)cc4)n[nH]c3c2)c1F +O=C1Nc2ccccc2C1=C1Nc2ccccc2C1=NOCCOC1OC(CO)C(O)C(O)C1O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccc(OC)cc1c2C1CCCC1 +CN1CC(n2nccc2-c2cc(F)ccc2Oc2cc(F)c(S(=O)(=O)Nc3cscn3)cc2Cl)C1 +N#Cc1c(N2CCC(c3ccccc3)CC2)ccn(CC2CC2)c1=O +COc1cccc(OC)c1C1COC(=O)N1Cc1ccc(OC(F)(F)F)cc1 +CCC(=O)CCCCCC(NC(=O)C12CCN(CC1)CC2)c1ncc(-c2ccc3ccccc3c2)[nH]1 +O=C(O)CC(NC(=O)Cn1cc(CCCNc2ccccn2)nn1)c1ccc(O)cc1 +CC(=O)c1ccc(N2CCC(OC(=O)N3CCN(C4CCC4)CC3)CC2)nc1 +CCOc1ccc(NC(=O)c2cccc(-n3ncc4cc(Nc5ccccc5F)ccc43)c2)cc1OC +CCC1(C)OC(=O)C(OC(C)C)=C1c1ccc(S(C)(=O)=O)cc1 +CCCNC(=O)C(NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c(C)c1)c1ccccc1 +CC1CC(N)CN(c2ccncc2Nc2ncc3ccc(-c4ncccc4Cl)nn23)C1 +COc1ccc(S(=O)(=O)N(Cc2cccnc2)c2c(C)cc(Br)cc2C(=O)NO)cc1 +O=C1C(=C(O)c2ccccc2)C(=O)N(c2ccc(Cl)cc2)N1c1ccc(Cl)cc1 +COc1cc(CCN(C)C)c2sc3c(O)c(OC)cc(CCN(C)C)c3ssc2c1O +O=c1c2cn[nH]c2c2ccc(-c3cccc(N4CCOCC4)n3)cc2n1CC(F)(F)F +O=C(O)c1cc2cc(OCc3c(Cl)cccc3Cl)ccc2n1Cc1ccc(O)cc1 +[C-]#[N+]c1ccc(Oc2ccc(-c3nc(C(N)=O)cc(C(O)CO)n3)cc2)cc1C(F)(F)F +O=C(CN1CCC(C(=O)c2ccc(Cl)cc2)CC1)NCc1nc2c(c(=O)[nH]1)COCC2 +COc1ccc2nc(C)c3c(C)nc(-c4c(C)nn(C)c4C)n3c2n1 +ON=c1cc(-c2cc3cccn3cn2)oc2ccc(OCCN3CCOCC3)cc12 +CN1CCC(Cn2c(CN(C)C3CCCc4cccnc43)nc3ccccc32)C1 +CCC1CCN(c2c(F)cc3c(=O)n(N)c(=O)n(C4CC4)c3c2C)C1 +CC(C=CC1CC2(CO2)CC(C)(C)O1)=CCC1CCC(NC(=O)C=CC(C)OC(=O)C(F)(F)F)CC1 +COc1ccc(C2OC(CO)C(O)C(O)C2O)cc1Cc1cc2cccccc-2c1 +O=C(NCc1ccc(F)cc1)c1c(O)c2ncc(Cc3ccccc3)cc2n(CCN2CCCC2=O)c1=O +CCCCCCN(C)CNCC(=O)C(CC(=O)O)NC(=O)C(CC)n1cc(CC)nc(NCc2nonc2C)c1=O +COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1 +Cc1c(Cl)cccc1S(=O)(=O)NCC(C)(C)C(=O)NC1C2CC3CC1CC(C(N)=O)(C3)C2 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCOc3ccc(F)cc3)c2)c1 +NC1CCCCC=CCC(C(=O)NCc2ccccc2CC(=O)O)NC(=O)C(Cc2ccc(O)cc2)NC1=O +Cc1cc(-c2nnc(N)nc2-c2ccccc2)cc(C(F)(F)F)n1 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3cc(F)ccc31)CC2 +CCS(=O)(=O)c1cccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)c1 +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Nc1ccc(NC(=O)c2cscn2)cc1 +Fc1cccc(F)c1Cn1c(-c2c(F)cccc2F)nc2c(CCl)cccc21 +Cc1cccc(C)c1Nc1nc2cccc([N+](=O)[O-])c2n2cncc12 +CCCCCn1cc(CC(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(Br)ccc21 +Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)c(Cl)c1 +NCC1CCCN1C(=O)C1CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +NC1=NC2(CCOCC2)N(OCCCOc2cc(Cl)c(Cl)cc2Cl)C(N)=N1 +CNC(C)C(=O)NC(C(=O)N1CCC2CCC(NC(=O)c3ccc4ccccc4c3)C21)C(C)(C)C +O=C(O)c1ccc(Nc2ncc(F)c(Nc3ccccc3C(=O)O)n2)cc1 +CN1CC2(CNC(=O)c3c2[nH]c2c3CCc3cnc(-c4cccc(F)c4)nc3-2)C1 +O=S(=O)(Nc1nc(NCCc2ccccc2)nc2c1CN(Cc1ccccc1)CC2)c1ccc(Cl)c(Cl)c1 +Nc1ncc(-c2cc(N3C4CCC3COC4)nc(N3CC4CC3C4)n2)cn1 +COc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1OC +O=C(NO)C1Cc2ccccc2CN1S(=O)(=O)c1ccc2oc3ccccc3c2c1 +O=C(Nc1nc2ccc(C(=O)N3CCC(NCc4ccc5ccccc5c4)CC3)cc2s1)C1CCCCC1 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+O=Cc1ccc(C2=CCC(N(CCN3CCCC3)C(=O)Nc3ccc(F)c(Cl)c3)CC2)o1 +N#Cc1cc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)ccc1OC1CCCC1 +Oc1cc(Nc2nccc(-c3nccs3)n2)cc(C(F)(F)F)c1 +N#Cc1cc2c(O)c(-c3ccccc3)c(O)nc2cc1Cl +Cc1ccc(C(=O)Nc2cccc(NC(=O)C(C)N)n2)nc1 +O=C(Nc1nccc2nc(-c3c(F)cccc3Cl)sc12)NC1CC1 +COc1cc(OC)cc(N(CCCN2CCC(F)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CNC(CC(C)C)C(=O)NC1CCC2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)CC21 +CCC(CC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1 +CC(C)(N)C(=O)NC(CCC(F)(F)c1ccccc1)c1nnnn1CCOC(=O)NCCCCO +Cc1ccc(C2CC2COc2nc(C)ncc2-c2ccn(CC(F)F)c(=O)c2)nc1 +O=C(Nc1ccc(C2=CCN(CC3CCOC3)CC2)cc1)N1Cc2ccncc2C1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncnc2c1ncn2CC(=O)O +Cc1cc(NC(=O)Nc2ccc(F)c(C(F)(F)F)c2)ccc1Oc1cc(NC(=O)C2CC2)ncn1 +CC(Oc1nc(C(=O)N(C)C(C)(C)C)ccc1C1CC1)C(F)(F)F +NC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCCC3=O)cc2)ncc1Cl +Cc1nc(N2CCN(C)CC2)cc(-c2ccccc2)c1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1ccc(-c2cc(C(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)cc1C +Fc1ccccc1N1CCN(Cc2cn(-c3ccccc3)c(-c3ccccc3)n2)CC1 +O=C(c1ccc(-c2ccc(F)cc2F)s1)c1c(F)ccc(O)c1F +CCCCNC(=O)CC(O)C(COCc1ccc(-c2ccccc2)cc1)NC(=O)C(NC(=O)c1ccccn1)C(C)C +COc1cc(S(=O)(=O)N2CCOCC2)ccc1NC(=O)COC(=O)c1ccccn1 +Cc1nc(-c2nnc3n2CCN(C(=O)c2ccc(F)cc2)C3C)cs1 +CCOCN1C2=C(C(=O)Nc3ccc(OC)cc3F)C(=O)CCN2c2ccc(F)cc21 +COc1cc(C=CC(=O)N2CCC(n3c(O)nc4ccccc43)CC2)c([N+](=O)[O-])cc1OC +COc1cc2c(cn1)C(Oc1ccc(Cn3c(N)nc4cc(-c5cnn(C)c5)cnc43)cc1OC)CCC2 +CC1=C2CCc3cc(-c4ccccc4)ccc3N2CCC1=O +CN(C(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21)c1ccccc1 +Cc1ccc(C)c(S(=O)(=O)N(C)N=Cc2cnn3ccc(C#N)cc23)c1 +Cc1cccc(Nc2ccccc2C(=O)NCCCCCCCNc2c3c(nc4cc(Cl)ccc24)CCCC3)c1C +CCCCC(NC(=O)OCC1(COc2nc(-c3ccccc3)cs2)CCC1)C(=O)C(=O)NC(C)c1ccccc1 +Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccc(CN2CCN(C)CC2)cc1 +COc1ccc2c(c1)c1cc(C(=O)NCCN(C)C)c3ncccc3c1n2C +COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC +Cn1nc(CC(CC(=O)O)c2cnc(-c3ccc(Cl)cc3)s2)cc1OCCc1ccc2c(n1)NCCC2 +O=C(c1ccc(Cl)cc1)N(CC1CC1)c1nnc(-c2cccc(F)c2)s1 +Cc1cnc(N2CCN(C(=O)C3CCS(=O)(=O)CC3)C(c3ccccc3F)C2)nc1 +O=c1ccn2c(-c3ccc(F)cc3F)cccc2c1-c1cc(-c2nnco2)ccc1F +CCc1ncnc(-c2ccc(C(=O)N3CCN(C4CCOCC4)CC3)c(OC)c2)c1C#Cc1ccc(N)nc1 +O=C(Nc1ccc2nc(C3CC3)c(C3CC3)n2c1)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 +COc1cccc(COc2c(C(C)=O)c(O)c(OC)c3occc23)c1 +CC(Nc1nc(Nc2cn(C)cn2)c2cccnc2n1)c1ncc(F)cn1 +NS(=O)(=O)c1ccc(-n2nc(COCc3ccccc3)cc2-c2ccc(Cl)cc2)cc1 +COP(=O)(O)OP(=O)(O)OCC1OC(n2ccc(=O)[nH]c2=S)C(O)C1O +CC(C)NC(=O)c1c[nH]c2ncc(Oc3ccc4c(c3)CCC4)nc12 +CSc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)cnc34)c3ccccc23)cc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(-n4cnc(CCNC(C)=O)c4)cc3)NC(=O)NC1=O)C2 +N#CCc1ccc(Nc2ncnc3ccc(-c4cccc(O)c4)cc23)cc1 +CCOc1ccc(C)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 +CC1CCCN1CCc1cc2cc(C(=O)c3ccccc3)ccc2o1 +c1ccc(-c2ccc3ncnc(Nc4cccc5[nH]ncc45)c3c2)cc1 +O=C(CCCCCCCOc1ccc(-c2nc(N3CCOCC3)c3sccc3n2)cc1)NO +O=C(C=Cc1ccc2[nH]c(C(=O)c3ccccc3)cc2c1)NO +O=C1CCOc2c(OCCNCCCCc3ccc(O)cc3)cc(F)cc21 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(Oc2cccc(Cl)c2C#N)cc1 +O=C(NCCN1CCOCC1)c1cc(-n2ncc3cc(Nc4c(Cl)cccc4Cl)ccc32)ccn1 +CCCCc1ccc(N2CCN(CCn3c(=O)[nH]c4c([nH]c5ccccc54)c3=O)CC2)cc1 +O=C(C=NNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])NCCCCCCCNc1ccnc2cc(Cl)ccc12 +CCC(O)(CC)C1CC(Nc2nc(NCCOC)nc(C)c2-c2nc3c(C)nccc3s2)C(O)C1O +CCCCn1cc(CCCOc2ccc(C(=O)NCCCN3CCCN(c4ccc(O)c5[nH]c(=O)ccc45)CC3)cc2OC)nn1 +COc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2NCCCO)cn1 +COc1ccc(C2=NOC(C(=O)NCc3cccs3)C2)cc1OC +CCCCC(=O)c1cccc2c(C)c(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)sc12 +Cc1cc[n+]([O-])c(C)c1C(=O)N1CCC(C)(N2CCN(C(C)c3ccc(C(F)(F)F)cc3)C(C)C2)CC1 +Cc1c(-c2ccccc2Cl)cc(F)c(Nc2ncccc2C(=O)O)c1F +NC(=O)c1ccc2c(c1)CCOC2CCN1CC=C(c2cccc3ccccc23)CC1 +COc1cccc2c1c(NS(=O)(=O)c1ccc(Cl)s1)nn2Cc1cccc(CN(C)C(C)=O)c1 +O=C(O)c1ccc(Nc2ncc(-c3ccncc3)c(Nc3ccccc3)n2)cc1 +COc1cc2nc(N3CCN(C)CC3)cc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(n1cc(CCC(=O)OCc3ccc(F)cc3)nn1)CC2 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NCC3CCCCC3)CC2)c(C)c1 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+CC1CCCC(N2CCC(c3c(F)ccc(Cl)c3F)=CC2=O)c2cc(ccn2)-c2ccc(Nc3ccccn3)cc2NC1=O +Cc1ncccc1N1CCC(Cc2ccc3oc(-c4cc5sccc5cn4)cc(=NO)c3c2)CC1 +O=C(NCCF)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(C4CCC5(CC4)OCCO5)c3n2)cc1 +CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)on2)CC1 +COc1cc2cc3c(Nc4cc(OC)c(OC)c(OC)c4)c(C#N)cnc3cc2cc1OCCN1CCOCC1 +Clc1ccc(CNc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)cc1 +OC(CCc1ccccc1)CN1CCC(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +CC(C)CC(C(=O)NC(Cc1ccccc1)C(=O)c1c[nH]c2ccccc12)C(O)C(=O)NO +O=S1(=O)C(c2ccccc2)CCCCN1Cc1cc(F)c(N2CC3C(C2)C3n2cnnc2)cc1F +COc1cc(C(=O)NC(=S)Nc2ccc(C)c(NC(=O)c3cccc(-c4ccccc4)c3)c2)cc(OC)c1OC +CCc1nnc2n1-c1ccc(C#CCN3C(=O)c4ccccc4C3=O)cc1C(c1ccccc1F)=NC2 +CS(=O)(=O)c1ccc(-c2[nH]c3ccc(F)cc3c2-c2ccccc2)cc1 +CS(=O)(=O)c1cccc(-c2nc(C(c3ccc(F)cc3)c3ccc(F)cc3)sc2CC(=O)O)c1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C(N)=O +O=C(NCC(Cc1ccccc1)N1CCC(C(F)(F)F)CC1)C1(c2ccc(Cl)cc2)CCCC1 +CN(C(=O)C=CCC(C)(C)N)C(Cc1ccc2ccccc2c1)C(=O)N(C)C(Cc1ccccc1)C(=O)NCC1CC1 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+O=C(c1n[nH]c2c1CN(CC(F)(F)F)CC2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 +NS(=O)(=O)c1ccc(CNS(=O)(=O)C2OC(C(=O)O)C(O)C(O)C2O)cc1 +NC(=O)CNC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc3c(c2)OC(OC)O3)cc1 +CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2cccnc2C(=O)O)cc1 +CCCC(Oc1ccc(-n2cc3cc(F)ccc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 +Nc1ccc(Cl)cc1C(=O)NC1CCN(Cc2ccc3c(c2)OCO3)CC1 +O=C(NCc1cc(Br)cc2nc(O)c(O)nc12)c1ccco1 +O=CN(O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)c1ccccc1 +CC(=NNc1ccc(S(N)(=O)=O)cc1)c1cc2cc(Cl)ccc2oc1=O +CC(C)CC(NC(=O)C(Cc1c[nH]c2ccccc12)NS(C)(=O)=O)B(O)O +c1ccc(-c2cnc3nc(N4CCN5CCC4CC5)oc3c2)cc1 +N#CC(C#N)=C1N(CCCCN2CCCCC2)CCN1CCN1CCCCC1 +Cc1cccc(C)c1Oc1ccc(C#N)c(C(F)(F)F)c1 +O=C(O)CNC(=O)c1c(O)cc(-c2cc(F)cc(Cl)c2)c2ncnn12 +NC(=NCc1ccccc1)Nc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +Nc1nc(NCC2CCCN2Cc2cc3ccccc3o2)nc2nc(-c3ccco3)nn12 +OCC1OC(c2cc(Cc3ccc(C4CCCC4)cc3)c(Cl)c3c2CCO3)C(O)C(O)C1O +O=C(NCCCCc1ccc(Cl)c(Cl)c1)c1ccccc1CNCCc1ccc(O)cc1 +CC(C)(NC(=O)C(NC(=O)C(CCCc1ccccc1)CC(=O)O)C(C)(C)C)c1ccccc1 +COC(=O)c1ccc(NC(=O)c2cccc(-c3cn4ccnc4c(Nc4ccc(OC)c(OC)c4)n3)c2)cc1 +COC1CCC2(CCc3ccc(Br)cc3C23N=C(C)C(N)=N3)CC1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc([N+](=O)[O-])cc4)cc3F)ccnc2cc1OCCCN1CCCC1 +CC(=O)N(CC(CC(C)C)N1CCN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2F)CC1)C(C)C +Cc1ccc(C=C2SC(=S)N(CCCC(=O)NNC(=O)c3ccccc3O)C2=O)cc1 +CN1CCCC1Cc1c[nH]c2ccc(C3=CCN(C(S)=NC45CC6CC(CC(C6)C4)C5)CC3)cc12 +CC(C)c1cccc(C(C)C)c1N(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC1CCCCC1 +COc1cccc(C#Cc2c(-c3ccccc3)oc3cc(O)c(C(=O)O)cc23)c1 +Cc1ccc(F)cc1Oc1c(C(=O)N2CCNCC2)c2ccccc2n1C1C=CCCC1 +Cn1c(NCCN(CCO)CCCc2ccc([N+](=O)[O-])cc2)cc(=O)n(C)c1=O +COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCC1CCNCC1 +C=CC1(C)CC(=O)C2(O)C(C)(O1)C(OC(C)=O)C(O)C1C(C)(C)CCC(O)C12C +CC(=O)c1cccc(OCc2ccc(C(F)(F)F)cc2)c1 +CN1C(=O)c2[nH]c(Cc3ccccc3)nc2N2CC(Cc3ccccc3)N=C12 +COc1cc(Nc2cccc3c2nc(Cc2ccc(F)cc2)n3C)ccc1-n1cnc(C)c1 +CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc([N+](=O)[O-])s2)c1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(OC2C3CC4CC(C3)CC2C4)cc1F +O=C(NCCCCNc1ccnc2cc(Cl)ccc12)c1cccc(Br)c1 +CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)cn4)c3CO)ncc2c1 +O=C(Nc1ccccc1C(=O)O)c1cc(O)c(Br)c(Oc2ccccc2)c1 +CCN(C(=O)OCCCO[N+](=O)[O-])C1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +Cc1ccc2c(c1)sc1nc(-c3ccc(Br)cc3)cn12 +CCOc1ccc(Nc2nc(=O)n(CC(C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1C +CCN1CCC(N2CCC(c3cc(NC(=O)c4cnn5cccnc45)n(-c4ccc(C)cn4)n3)CC2)CC1 +CC(C)(C)C(NC(=O)C(CC1CCCC1)CN(O)C=O)C(=O)c1ccc(N2CCN(CCO)CC2)c(F)c1 +CC(C)Oc1nccc2[nH]nc(-c3cc(C(=O)N4CCOCC4)n(C(C)C)c3)c12 +CC1CCN(S(=O)(=O)c2cccc(-c3ccccc3)n2)CC1 +CCOC(=O)c1nc(-c2ccc(NC(=O)Nc3ccc(NS(C)(=O)=O)cc3)cc2)nc(N2CCOCC2)c1OCC +CC(C)(NC(=O)CCNCC(=O)N1CCCC1C#N)c1ccccc1 +COc1ccc(Br)cc1CCc1c(Cl)cccc1C1=NCCN1 +CS(=O)(=O)c1ccc(S(=O)(=O)n2c(C3(O)C=CC(=O)C=C3)cc3ccccc32)cc1 +CCCN(c1nc(-c2ccc(OC)cc2C)n(C)n1)C(CC)c1ccc(C(F)(F)F)cc1 +OC1C(O)C(n2cnc3c(NC4CC4c4ccccc4)nc(Cl)nc32)C2CC12 +CC1CN(c2noc(C(C)(C)O)n2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)nc31)CNCC2 +COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cccnc3n(CCC(C)C)c1=O)N2 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)c3cccnc3)c2cn1)c1ccccc1 +Cc1cc(C(=O)NCC[N+]2(C)CCCCC2)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +CCNCc1cncc(-c2cnc3c(c2)C(c2nc4cc(F)ccc4[nH]2)N=N3)c1 +O=S(=O)(c1ccc(-c2nnn[nH]2)cc1)N(CCC1CC1)c1cc2ccccc2s1 +COCCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NC4CC4)ccc3C)c2c1C +CN1CCN(c2ccc(-c3cnc4[nH]c5cnc(C(N)=O)cc5c4c3)cc2)CC1 +CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1NC(=O)c1ccc(OC)cc1 +COc1ccc(OCCCOc2ccc3c(c2)CCC3CC(=O)O)cc1 +O=S(=O)(Nc1nncs1)c1ccc(Oc2ccc(OC(F)(F)F)cc2-c2ccnnc2)c(Cl)c1 +CN1CC(NC(=O)c2c(C(N)=O)nc3n2CCOc2cc(F)c(C#CC(C)(C)O)cc2-3)C1 +OCCN(CCO)c1c(Br)cccc1Nc1ncnc2ccncc12 +Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(C(=O)CCC(=O)O)ccc12 +COc1cccc2nc(C=Cc3nc4c(C)ncc(C)n4n3)ccc12 +O=C(C=Cc1ccc2c(c1)nc(-c1ccccn1)n2CCCO)NO +CC(C)(C)c1ccc2c(c1)C(=O)c1ccc(C3=NCCN3)cc1S2(=O)=O +O=c1n(Cc2ccc(F)c(F)c2)ccn1-c1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cc1 +COC(=O)C(NC(=O)NC(C(=O)NC1CCCCNC(=O)C=CC(Cc2ccccc2F)NC1=O)C(C)C)C(C)C +NC(CCC(=O)NC(CSC(C(=O)O)c1ccccc1)C(=O)NCC(=O)O)C(=O)O +c1ccc(C2CCN(Cc3ccn(-c4ccccc4)c3)CC2)cc1 +COC(=O)N(CC(=O)O)Cc1cccc(OCc2csc(-c3ccc(Cl)cc3)n2)c1 +O=c1c2ccccc2nc(C(F)(F)F)n1-c1ccccc1 +CN(C)C(=O)c1cnc(-c2ccc3c(c2)Oc2ccccc2C3C(C)(C)C(=O)Nc2nncs2)nc1 +NC(=O)c1cccc2c(NC(CCN3CCCC3)c3cccc(NC(=O)c4ccc(F)cc4F)c3)ncnc12 +NC(=O)c1cc(F)cc2[nH]c(-c3ccc(-c4ccc(NC(=O)C5CC5)cc4F)cc3F)nc12 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)nc(OCCO)n1 +CCCC(=O)NCC1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COc1cccc(Cn2c3cc(C)sc3c3cnn(C)c(=O)c32)c1 +CCn1nc(-c2cnccc2C)c2ncc(OCc3ccccn3)nc21 +COc1c(Cl)cccc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 +Fc1ccc(-c2ccc3ncc(-c4ccncc4)n3n2)cc1F +O=C(Nc1ccc(O)cc1)c1c(N2CCCCC2)cc(-c2ccccc2)oc1=O +CCOc1cccc(-c2c[nH]c3ccc(-c4nnc(NC)s4)cc23)n1 +COc1ccc(OC)c(S(=O)(=O)N2CCC(N3C(=O)OCc4cccc(C)c43)CC2)c1 +O=C(CN1CCOCC1)NC1CCCC(Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1 +OCC(NCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1F)C1CC1 +COCCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCCCCC(=O)NO +Nc1nc(Nc2ccc(N3CCN(C4CC5CCC4C5)CC3)c(F)c2)nn1-c1ncnc2ccsc12 +O=C(c1cc2c(O)cc(O)cc2[nH]1)N1CCC(Cc2ccccc2)CC1 +N#CC1CCCN1C(=O)C1CCC=C1C(=O)CCCc1ccccc1 +Cc1csc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)c1 +COC(=O)C1C2CC3CCC1N3CC2=Cc1ccc(C(C)C)cc1 +COc1cc(C(=O)NS(=O)(=O)c2ccccc2C)ccc1Cn1ccc2ccc(C(=O)NCC(C)CC(F)(F)F)cc21 +CC1(C(=O)NC(Cc2ccc(O)cc2)C(=O)O)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)=NNC(=O)C2 +NS(=O)(=O)c1ccc(OC2c3ccccc3CC2N2CCCC2)c(Cl)c1Cl +CN(C)C1CCC(Nc2ncnc3sc4ccc(C(N)=O)cc4c23)CC1 +Nc1nc(C(=O)NCc2cccc3cccnc23)c2cccc(Br)c2n1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(C=Cc4cc(C)cc(C)c4)cc3)ncc2F)c1 +Cc1ccc2[nH]c(CNC(=O)c3ccc4c(c3)CNC(=O)C(CC(=O)O)N4)nc2n1 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCCCN1C(=O)c2ccccc2C1=O +Cc1c(Br)c(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1Br +CCCCCCCn1c(=N)n(CC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2ccccc21 +C#Cc1cccc(Nc2ncnc3cc(OC)c(NC(=O)CCCCC(=O)NO)cc23)c1 +Cc1cccc(Nc2ccccc2C(=O)NCCCCCCCCCCCCNc2c3c(nc4cc(Cl)ccc24)CCCC3)c1C +O=C(O)Cc1ccc2c(c1)CC(NS(=O)(=O)c1ccc(Cl)cc1)C2 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cccc(C#N)c1 +O=C(Nc1c(Cl)ccnc1Cl)C(=O)c1cc(Cc2ccc(Cl)cc2)n2ccccc12 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3cn[nH]c3)nc21 +CN1C(=O)N(c2cn(C)cn2)CC1C(=O)NCc1ccc(Cl)cc1Cl +CC(C)(C)C(=O)N1Cc2n[nH]c(=O)c3cc(F)cc4[nH]c(c2c43)C1 +CC1CN(Cc2c[nH]nc2-c2c[nH]c3ncccc23)CCN1c1ccc(C(F)(F)F)cn1 +O=C(OC1CCCC1Oc1ccc(O)cc1)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1 +Nc1ncc(-c2cnn(CC(=O)N3CCOCC3)c2)c2scc(-c3ccc(Oc4ccccc4)cc3)c12 +CCCCC(NC(=O)OC(C(C)C)C(C)C)C(=O)C(=O)Nc1[nH]ncc1Br +Cc1ccc(S(=O)(=O)N(CC(C)C)C(CCCCNC(=O)C(O)Cc2ccccc2)C(=O)O)cc1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccccc3C)cc12 +CCC(CCCCCn1c(C)nc(-c2ccccc2)c1-c1ccccc1)NC(=O)Oc1ccccc1F +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)Nc1ccc2ncccc2c1 +O=C(O)c1cc(F)cc(-c2ccccc2-c2ccccc2OCc2ccccc2)c1 +CNC(=O)Nc1ncc(SCC2CCOCC2)cc1Oc1cccnc1C +COc1cc2nccc(Oc3ccc(NC(=O)Oc4ccccc4)cc3)c2cc1OC +CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(-c2ccc(C)cc2)n1 +NS(=O)(=O)OCC1CC(n2cnc3c(NC4CCc5ccccc54)ncnc32)C(O)C1O +COc1ccc2c(c1)c1c(n2C)CCCCC1CNC(=O)C1CC1 +CC1C(=O)NCC1C(=O)Nc1cc(-c2cccc(OC(F)(F)F)c2)n(C2CCC(F)(F)CC2)n1 +CCCc1cnc(N2CCC(C3Cc4cc(N5CCN(S(=O)(=O)CCC)CC5)ccc4O3)CC2)nc1 +Fc1cccc(Cl)c1-c1nc(-c2ccc(C=Cc3ccccc3)cc2)c[nH]1 +OCCCCCCCCCCCCCc1ccc[n+](CCCCCCCCCCCCCc2cccnc2)c1 +CN(c1ncnc2[nH]ccc12)C1CCC(CS(=O)(=O)N2CCC(CO)(CCO)C2)CC1 +CC(=O)N(c1ccccc1)c1ccc(C(=O)NCCCCCCC(=O)NO)cc1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(OC)cccn12 +COCC1CNC(C)CN1CC(=O)N1CC(C)(C)c2cnc(C(C)(F)F)cc21 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5COCC4CC(=O)C5)cn3)n2)s1 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)Nc3ccccc3C(=O)c3ccccc3)CCC12 +CC1CCC(C)N1CCc1cc2cc(-c3ccc(C#N)cc3)ccc2o1 +CN1CCN(Cc2cccc(-c3cc(NCCCN4CCCC4)c4ccccc4n3)c2)CC1 +N#CCNc1ncnc(-n2c(Nc3cccc(O)c3)nc3ccccc32)n1 +COc1cc(Cl)c(-c2nc(SC(C)C)nc3[nH]cc(C#N)c23)cc1OCCN1CCC(F)(F)C1 +Cc1cccc(NC(=O)NCc2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)c1 +Nc1cc(CN2CCC(C(=O)N3CCC(n4c(=O)n(CCN5CCOCC5)c5ccccc54)CC3)CC2)ccn1 +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(C#N)c3)n3c2CCOC(CF)C3)ccn1 +NC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c5cc6ccccc6cc5oc2c34)C1 +CCc1c2c(nc3ccc(O)cc13)-c1ccc(O)cc1OC2 +Clc1cccc(-c2nc3ccn(Cc4ccc(Br)cc4)cc-3n2)c1 +CCCCCCC(=O)Nc1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +COc1ccc(Oc2cc(N3CCC(Oc4ncc(F)c(N)n4)CC3)ncn2)cc1 +CC(C(=O)NCCF)c1ccc(OC2CCN(c3nc(N(C)C)ncc3F)C2)cc1 +O=C(CCC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1)NC(Cc1ccccc1)C(=O)O +COc1ccc(C=CC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC2CCCc3ccccc32)cc1OC +CC1(COc2ccc(-c3ccc(F)nc3F)cn2)CCn2cc([N+](=O)[O-])nc2O1 +O=c1[nH]c(C2CC(F)CN2)nc2c1oc1ccc(Br)cc12 +C=CC1(CO)C=CC(n2cc(C)c(=O)[nH]c2=O)O1 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(S(=O)(=O)N4CCN(C)CC4)cc3)cc12 +CCCS(=O)(=O)NCCCc1ccc2c(c1)C(Cc1ccc(Cl)cc1)C(NC(=O)OC(C)(C)C)CC2 +N#Cc1cccc(-c2ccc(COCCCCCN3CC(O)C(O)C(O)C3CO)cc2)c1 +CC(Cc1ccc(F)c(F)c1)C(=O)NC1N=C(c2ccc3c(c2)OCO3)c2ccccc2N(CC(=O)N(C)C)C1=O +Cc1nc(C)c(-c2ccnc(Nc3cccc(Cl)c3)n2)s1 +COc1ccc(CN2CCC(NC(=O)c3cc(=O)c4ccc(F)cc4o3)CC2)cc1 +O=C(O)c1cc(N2CCOC2=O)cc(N2C(=O)C3(CC3c3ccc(Cl)cc3)c3ccccc32)c1 +CC(C)(C)c1cc(NC(=O)C2CCCCN2C(=O)c2ccc(Cl)cc2)no1 +CCC(NC(=O)CCc1cc(-c2ccc(-c3ccccc3)cc2)no1)C(=O)NC(CC(=O)O)C(N)=O +O=C(O)CC(NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1)c1ccc(-c2ccccc2OC(F)(F)F)cc1 +NC(=O)COc1cc(-c2cnn(CCO)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(SCCNC(C)=O)ccn34)c12 +CN1C2C=C(c3ccc4c(c3)Cc3ccccc3-4)CC1CC2 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3cn4ccccc4n3)c2)c2cncnc21 +COc1cc(S(=O)(=O)c2ccc(OC(F)F)cc2)cc2c3c(oc12)CCNC3 +CC#CCn1c(=O)c2c(-c3cncn3C)n(Cc3ccnc4ccc(Cl)cc34)nc2n(CC2CC2)c1=O +[O-][S+](Cc1cc(OCc2ccc(F)cc2)ccn1)c1nc2cscc2[nH]1 +CCC(C)Nc1cc(-n2ncc3cc(Cl)c(N)nc32)ncc1C(=O)NCC(F)C(C)(C)O +C=CC=CC(C)C(OC(N)=O)C(C)C(O)C(C)CC(C)=CC(C)C(O)C(C)C=CCCc1ccccc1 +COc1cc2c(cc1OC)CN(CCNC(=O)c1cc(Br)c3ccccc3c1OC)CC2 +CN(C)CCCN(Cc1ccccc1)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 +Fc1ccc(C(CCCN2CCC(c3noc4cc(F)ccc34)CC2)c2ccc(F)cc2)cc1 +CCC(O)(CC)C(F)CNC(=O)c1cnc(-n2ncc3cncnc32)cc1NC(C)C +COc1ccc(C=CC(=O)c2ccccc2-c2ccc(OC)c(OC)c2OC)cc1O +CCOC(CC(=O)O)c1ccc(OC2CCc3c2cccc3C(F)(F)F)nc1 +CCN1c2ncc(COc3cccc(O)c3)cc2C(=O)N(C)c2ccc(Cl)nc21 +COc1cc(N2CCC(N)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2ccc(NC3CCN(C(=O)c4ccccc4Cl)CC3)nc2)c1 +NCc1ccc(C(=O)Nc2ccncc2)cc1-c1cccc(C(=O)OCc2ccccc2)c1 +O=C(O)COCC1CCC(CNC(=O)N(c2ccccc2)c2cccc(Cl)c2)CC1 +CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2Cc2ccco2)cc1 +COc1cc(OC)c2c(c1)OC(c1cc(OC)c(OC)c(OC)c1)C(OC(=O)Cc1cc(OC)c(OC)c(OC)c1)C2 +Cc1c(C(=O)c2nccn2C)oc2cccc(OCCCNCc3cccnc3)c12 +Cn1c(Nc2c(Cl)ccc(CNC(=O)C(C)(C)C)c2Cl)nc2cc(C(=O)NC3CC4CCC3C4)c(OCC(F)F)cc21 +Cc1ccc(-n2cc(C(=O)NCCC(=O)Nc3ccc(C4CCC(CC(=O)O)CC4)cc3)c(C(F)(F)F)n2)cc1 +CN(C)C(=O)C(CC1CC1)NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 +CCCNc1nc(SCc2ccc([N+](=O)[O-])cc2)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Cc1ccc(CCc2cc(-n3nc(C)nc3C)nc(C)n2)nc1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC3CCCCC3)n1)C1(CC1)CN2 +O=C(Nc1cccc(-c2cn3ccnc3c(OCc3ccncc3)n2)c1)Nc1cccc(C(F)(F)F)c1 +O=C(O)c1cncc(-c2ccc(N3CCC(Oc4ccccc4Br)CC3)nn2)c1 +CC12CCC3c4cc(Cl)c(OS(N)(=O)=O)cc4CCC3C1CCC2=O +CNc1nc2cc(-c3cccc(CC(C)=O)c3)sc2n2c(C)cnc12 +CCOc1ccc(-c2nonc2NC(=O)c2ccco2)cc1OCC +Cn1c(CN2CCC(c3ccc(C(F)(F)F)cc3F)CC2)nc2ncccc21 +N#Cc1ccc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(C(=O)C(C)(C)N)CC2)CC1 +CCCCCCC(=O)OCC1(CO)CC(=Cc2ccc(OC)cc2)C(=O)O1 +COc1cc2ncnc(N(C)C3CCN(c4ncnc5[nH]ccc45)C3)c2cc1OC +Nc1ncc(C2CCCCC2)nc1-c1ccc(C(=O)NC(CO)c2cccc(Cl)c2)c(F)c1 +O=C1CC(O)CC(CC2c3ccc(F)cc3-c3cc(Cl)cc(Cl)c32)O1 +O=c1ccc(-c2cccc(C(F)(F)F)c2)nn1CC1CN(c2ncc(-c3cnn(C4CCNCC4)c3)cn2)CCO1 +O=C1CC(C(=O)Nc2cc(-c3cccc(COC(C(F)(F)F)C(F)(F)F)c3)n(-c3ccc(Cl)cc3)n2)CN1 +O=C(NC1CCN(C(=O)CCc2cccnc2)CC1)C(c1ccc(F)cc1)C1CCCCC1 +NC(=O)C(OC(=O)C=Cc1ccc(O)c(O)c1)C(OC(=O)C=Cc1ccc(O)c(O)c1)c1nnn[nH]1 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+CC(C)Oc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)cc3)ncc12 +CCc1nc2c(C(=O)NCc3ccccc3C(F)(F)F)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCCC5CCCCN5)s4)nc23)N1 +Cc1ccc(C)c(CN2CCOC(C(=O)N(Cc3cc(Cl)c4c(c3)OCCCO4)CC(C)C)C2)c1 +O=C(NCc1ccccc1)NCc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1 +COc1cccc(OC)c1C(=O)NCCSC1c2ccccc2COc2ccc(C(=O)O)cc21 +NC1CCCCN(c2ccncc2Nc2cccc3cnc(-c4c(F)cccc4F)nc23)C1 +CCCc1ccccc1OCCCOc1ccc2c(c1)CCC2CC(=O)O +CCC12CC(C(=O)OC)=C3Nc4cc(OC)c(O)cc4C34CCN(C(=O)C3OC31)C42 +CCCCc1ccc(OCCCCCC(O)C2CCC(C3CCC(C(O)CCCCCOc4ccc(CCCC)cc4)O3)O2)cc1 +O=C(O)CC(Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)c1n[nH]c(=O)o1 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3c(c2)CCCC3C(=O)O)cc1 +CCc1nn(Cc2ccc(-c3nc4ccncc4[nH]3)cc2F)c(CC)c1CC(=O)O +CN1CCC(COCc2cc(C(F)(F)F)cc(C3CC3)n2)(c2ccc(Cl)cc2)CC1 +COC(=O)C(C)(C)Nc1cc(C(N)=O)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +O=C1c2ccccc2CCCN1CCN1CCC(n2nnc3ccccc32)CC1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CC(O)C4)c4ccccc4n3)c(C)c12 +CC(C)(C)C(NC(=O)Cc1ccc(C#N)cc1)NC(=NC#N)Nc1cccc2ncccc12 +CCCn1c(-c2ccccc2)cc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)c1C +c1ccc(-c2nnc3c4c(c(OCc5ccncc5)nn23)C2CCC4CC2)cc1 +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3cccc4[nH]cc(C)c34)nc(N3CCC(O)C(C)(C)C3)c2C1 +COCC1CN(c2noc3cc(OCCCF)ccc23)C(=O)O1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(Cn3cccn3)c12 +CC(=O)Nc1c(Cl)cc(CNC(N)=NC(=O)C2CC(OCc3ccccc3)CN2c2ccccc2)cc1Cl +CC(C)C(CO)NCc1nc(C2CCCN(C(=O)OC(C)(C)C)C2)ccc1F +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCC#N)c12 +O=c1cc(OCc2ccc(C(F)(F)F)cc2)ccn1-c1ccc(OCCN2CCCC2)cc1 +CCc1c(S(=O)(=O)c2ccc(O)nn2)oc2ccc(Cl)cc12 +COCC1CNC(C)CN1CC(=O)N1CC2(CN(C(C)=O)C2)c2ccc(Cl)cc21 +CCc1ccc(N=C2SC(=Cc3ccnc(NC(=O)CCC(=O)O)c3)C(=O)N2C)cc1 +CC(=O)C1CCC2C3CCC4CC(O)C(N5CCOC(C(C)C)C5)CC4(C)C3C(=O)CC12C +COc1cccc(CN(C)C(=O)c2cc3ccc(-c4cn[nH]c4)cc3[nH]2)c1 +COc1ccccc1CN(C(=O)CF)c1cnccc1Oc1ccccc1 +CN(OCCNC(=O)Cc1c(C#N)ccc(NCC(F)(F)c2ccccn2)c1F)C(=N)N +Cc1cc(C)c(Oc2cc(NC3CCN(Cc4ccccc4C)CC3)nc3ncnn23)c(C)c1 +CCSC(=S)SCC(=O)CCCCCCC(=O)Nc1ccccc1 +CC(C)(c1ccc(Nc2nn(C3CCCCC3C#N)cc2C(N)=O)cc1)C(O)C(F)(F)F +OCC1CC(O)CCN1CCc1ccc(Nc2nc(-c3cccc(C(F)(F)F)c3F)cs2)cc1 +O=C(NCCCCc1cccnc1)c1ccc(-c2cccc(OC3=CC=CC=CC3)c2)cc1 +CC(=O)Nc1ccc(-c2ccnc(Nc3cccc(C#N)c3)n2)cc1 +COc1cccc(C2SC(c3ccc(F)cc3)=NN2C(=O)c2c(F)ccc(F)c2F)c1OC +CCCCCc1c(CC)c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn12 +Cc1ccc(-c2cc(C(=O)NC3CC3)cc(N3C(=O)OCC3C(C)C)c2)c(F)c1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)C4(C)CCCN4CC(C)C)ncn3)cccc2s1 +COc1ccc2c(c1O)C13CCN(C)C(C2)C1(O)Cc1c([nH]c2ccccc12)C3 +CCCOc1ccc(-c2ccc(-c3ccccc3Cl)n2CC(=O)N=C(N)NCCC2OCCO2)cc1 +COc1cccc(CNCC(O)C(Cc2cc(F)cc(F)c2)NC(=O)C(C)N2CCC(C(C)C)C2=O)c1 +Cc1nsc(-c2nnc3n2CCN(C(=O)c2ccc(C#N)cc2)C3C)n1 +CC(=O)NC1C(N)C=C(C(=O)O)OC1C(O)C(O)CO +CN1CCN(c2nc(N)nc3cc(-c4ccoc4)ccc23)CC1 +Cc1csc(NC(=O)c2cccc(Oc3ccccc3F)c2)n1 +O=C(NCc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)Nc1ccccc1 +Cc1cc(C)c(-n2c3ncccc3n3c(CN4CCC(CCc5ccccc5)C4)c(C)nc23)c(Cl)c1 +NC(=O)CC(N)C(=O)NC(Cc1ccccc1)C(=O)N1CC(OCc2ccc3ccccc3c2)CC1CCCN=C(N)N +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2cccc(Cl)c2)c(Cl)c1 +COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(C)(=O)=O +O=C(CCc1ccncc1)N(Cc1nc2c(c(=O)[nH]1)COCC2)Cc1cccs1 +CCCOc1ccc(CC(CC2CCCCC2)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 +NS(=O)(=O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2SC3)cc1 +COCC(=O)N1CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C(NC(=O)c2nc3c(s2)CN(C)CC3)C1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1 +CNC(=O)c1cccc(CCc2c(C(=O)O)[nH]c(=O)[nH]c2=O)c1 +Cc1cccc(N2CC(C)n3nc(COc4ccc(Cl)cn4)cc3C2=O)c1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2F)nc1-c1ccc(F)cc1C +CCCn1cc(Cc2ccc(C(=O)O)cc2OC)c2cc(NC(=O)OC3CCCC3)ccc21 +CC(C)(O)CC1CCC(c2ccc(N3CCOc4ncnc(N)c4C3=O)cc2)CC1 +Cn1cc(-c2cc3c(-c4ccccc4)n[nH]c3cn2)cn1 +CCOc1cccc(-n2cc(C(=O)N3CCN(c4cnc5ccccc5c4)CC3)nc2-c2ccc(C)cc2)c1 +CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(NS(=O)(=O)O)cc1)c1nc(-c2ccsc2)cs1 +O=C(Oc1cc(F)c(F)cc1F)c1cc2c(cn1)[nH]c1ccccc12 +CC(C)(C)OC(=O)N1C2CCC1CN(c1ccc(C(=O)Nc3ccccc3N)cn1)C2 +CN1CCCC(C(=O)Nc2ccc(-n3cc4cc(F)cc(C(N)=O)c4n3)cc2F)C1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc4c(c3)C(C)Oc3cccnc3-4)NC(=O)NC1=O)C2 +CCCCc1cc2[nH]c(C)nc(N3CCCCC3)c-2n1 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C)nc2C2CC(=O)N(C)C2)n1 +CCCCC(O)C1CC(Cc2ccc(F)cc2)CCN1CCCNC(=O)Nc1cccc(C(C)=O)c1 +Cn1ccc(CN(c2ccc3[nH]ncc3c2)c2nc(-c3ccccn3)cs2)n1 +Cc1ccc(Nc2nc(-n3cc(CO)cn3)nc3c2ncn3C2OC(CO)C(O)C2O)cc1 +c1ccc(Cn2nnnc2C(c2ccc(-c3ccccn3)cc2)N2CCCN(C3CCC3)CC2)cc1 +Cc1cn(C2C=CC(COP3(=O)OCc4cc(CCC(=O)OC(C)(C)C)ccc4O3)O2)c(=O)[nH]c1=O +CCOC(=O)C1(Cc2ccc(OCc3cc(CC)nc4ccccc34)cc2)CC1C(=O)NO +O=C(c1cccc(F)c1-c1cccnn1)N1C2CCC1C(Nc1cnc(C(F)(F)F)cn1)C2 +CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc(C(C)=O)cc3)ccc21 +CNc1cc(NS(C)(=O)=O)ccc1Nc1c2ccc(OC)cc2nc2c(C)cccc12 +CC1(c2cccc(NC(=O)c3cnc(OCC(F)F)cn3)c2)CCSC(N)=N1 +COc1cc(OC)nc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(N4CCOCC4)c3)cn2)n1 +c1ccc2c(c1)[nH]c1c[nH]c3c4ccncc4nc-3c12 +COc1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +CCc1cccc(NC(=O)N2CCc3nc(-c4cnc5ccccc5c4)nc(-c4ccccc4C)c3C2)c1 +CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)N(C)CCN +CCNC(=O)Nc1ncnc2c1ncn2C1OC(COP(=O)(O)O)C2OC(c3ccccc3)OC21 +CC(C)(C)c1cc(NC(=O)C(C)(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)no1 +CCCN(CCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)cc1 +COc1ccccc1N1CCN(CCN(C(=O)c2ccccc2I)c2ccccn2)CC1 +CCN(CC)CCOc1ccc2c(c1)C1(CCOCC1)c1oc3ccccc3c1C2=O +Cc1cccc2c(=O)[nH]c(-c3ccc(C(=O)N4CCN(CC5CC5)CC4)cn3)cc12 +Cc1cc(C)cc(Cn2c(=O)[nH]c3ccc(Cl)cc32)c1 +C=CCOC(=O)NCc1c(Cl)nc(CCCC)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1cc(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)ccc1NC(=O)Nc1ccccc1C +CCCC(C(N)=O)C(CC(F)(F)F)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O +Cc1cccc(NCNC2N=C(c3cc[nH]n3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)c1 +O=c1ccn(C2CCC(OCP(=O)(O)O)O2)c(=O)[nH]1 +COc1cccc(S(=O)(=O)Nc2cccn(CC(=O)NCc3ccc(C(=N)N)cc3F)c2=O)c1 +CC(Oc1cc(-n2cnc3ccc(OC4CCCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl +CCNc1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +CCOC(O)=C(C#N)C(=NC1CCCCN(CC(=O)N2CCCC2)C1=O)Nc1ccc2oc(C)cc2c1 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+CC(C)(O)C1CCN(Cc2nc3c(N4CCOCC4)nc(-c4c(F)ccc5[nH]ccc45)nc3s2)CC1 +CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCC2CCN(C(=O)C3NCCC3O)CC2)cc1 +COc1cc(C2=C(c3c[nH]c4ccc(Br)cc34)C(=O)NC2=O)cc(OC)c1OC +COCCOCCOCCOCCOCCOCC1CC23CCC1(OC)C1Oc4c(OC)ccc5c4C12CCN(CC1CC1)C3C5 +O=C1c2ccccc2C(=Cc2ccc(O)cc2)c2sccc21 +CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 +COc1ccc(C(=O)Nc2ccccc2-c2nnn(-c3ccc(C(F)(F)F)cc3)n2)cc1OC +CNC(C)C(=O)Nc1ccc2c(n1)CN(C1CCCCC1)C(=O)N2c1ccc(Cl)cc1 +COC(=O)c1cccc(NC(=O)C2(CN(C)C)CCN(c3ncnc4[nH]cc(F)c34)CC2)c1 +NCC(C(=O)Nc1ccc2cnccc2c1)c1cccc(C(F)(F)F)c1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)OCC3CCCC3)CC2)C1 +CC(C)(O)C(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +CCCc1ncc(Cc2ccc3c(C(F)(F)F)ccc(O)c3n2)c2cc(OC)c(OC)cc12 +Cc1cccc2cc(Cn3nc(-c4cn[nH]c4)c4c(N)ncnc43)n(-c3ccccc3Cl)c(=O)c12 +Cc1cc(=O)n2nc(N3CC(CN)C(c4cc(F)ccc4F)CC3=O)ccc2n1 +CCN(C)c1ccc(-c2cnc(N)nc2-c2ccccc2O)cc1 +COC1(c2nc(C#N)c(-c3cc(C(=O)N4CC(c5ccc(C#N)cc5)C4)ccc3C)[nH]2)CCOCC1 +NC1(c2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)CC1 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+COc1ccc(-c2c(C(=O)NC3CCN(C(C)=O)CC3)noc2-c2cc(Cl)c(O)cc2O)cc1 +Cc1ncc(CN2CCN(C(=O)OCc3ccccc3)CC2)n1Cc1ccc(C#N)cc1 +CCCCC(NC(=O)OC1CN(C(=O)c2ccc3cc[nH]c3c2)CC1(C)C)C(=O)C(=O)NC(C)c1ccccc1 +O=C(Nc1cc(Nc2cccc3c2OCO3)ccn1)C1CC1 +CCNC(=O)C1OC(n2cnc3c(NOC)nc(C#Cc4ccc(C(C)=O)cc4)nc32)C(O)C1O +COc1ccc(NS(=O)(=O)c2ccc(S(=O)(=O)N(C)C3CCCCC3)cc2)c2ncccc12 +C=C(C)CN(CC)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3CCc2ccccc2)cc1 +Cc1cc(C)c(S(=O)(=O)NC(CCC(=O)N2CCN(c3cccc(NC4=NCCCN4)c3)CC2)C(=O)O)c(C)c1 +Cc1cc(C2CCN(S(=O)(=O)C(C)(C)C(=O)NO)CC2)ccc1-c1cccc(OCCO)n1 +COc1ccc(C(CC(C)C)NC(=O)c2cc(COc3cccc(C#N)c3)ccc2CCC(=O)O)cc1OC +C#CCNCc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C +CCCn1ccc2c(NCc3cccc(OC(F)(F)F)c3)cccc2c1=O +CC(CO)N1CCN(C(=O)OC2CCN(c3ccc(C(N)=O)cn3)CC2)CC1 +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NC(CO)C(=O)O +N=C(N)c1cccc(NC(=O)c2ccc3c(c2)CN(CCc2ccccc2)C(=O)C(CC(=O)O)N3)c1 +COc1cc(OC)cc(C2C(C#N)=C(N)Oc3c2ccc2cc[nH]c32)c1 +CC#CC1(O)CCC2(Cc3ccccc3)c3ccc(O)cc3CCC2C1 +C=CC(=O)Nc1cccc(-n2c(=O)cnc3cnc(Nc4ccc(Cl)cc4)nc32)c1 +CCn1ncnc1COc1nn2c(-c3ccccc3F)nnc2cc1C(C)(C)C +Cc1cc(Nc2nc(Cc3c(Cl)cccc3Cl)c3nc[nH]c3c2C(N)=O)ccc1N1CCNCC1 +CCC1COC2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12 +CC1CN(c2nc(N3CCOCC3)c3sc(-c4ccccc4O)cc3n2)CC(C)O1 +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2cccc(OCCN(C)C)c2)cc1 +O=C1c2cc(F)ccc2N(CC2CCC2)C(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 +COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2nc3ccc(Cl)cn3c2C)cc1 +CCNC(=O)C(=O)C(Cc1ccc(C(C)(C)C)cc1)NC(=O)C(NC(=O)CCCCC1CCSS1)C(C)C +Cn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccnc3)cc21 +O=C(O)CCCOc1cc(-c2cncnc2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(NC(=O)CC(F)(F)F)C5)cn3)n2)s1 +CCCC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(OC)c3)cc2c1Nc1ccc(CN(C)C)cc1 +N#Cc1ccc(C(c2coc3ccccc3c2=O)n2ccnc2)cc1 +COCC1CN(c2ncnc3[nH]cc(-c4cccc(C#N)c4F)c23)CCO1 +CC(C)(C)CC(=O)N(CCCCCCN1CC(O)C(O)C(O)C1CO)C1CCCCC1 +CC(C)c1ccc(O)cc1Nc1ccnc(Nc2cccc(C(N)=O)c2)n1 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+N=C(N)NCCN1C(CCc2ccccc2)CCCC1CCc1ccccc1 +Oc1ccc(Cc2nnc3ccc(-c4cccnc4)nn23)cc1 +CCn1c(=O)ccc2cnc(Nc3cccc(OC(F)(F)C(F)F)c3)nc21 +CCN(c1ccc(NC(=O)COC(=O)CCc2nc3ccccc3n2-c2ccccc2)cc1)C(C)C +Clc1ccnc2[nH]c(-c3ccc(N4CCNCC4)cc3)cc12 +CN1CCc2nc(C(=O)NC3CCCCC3CNC(=O)c3ccc(Cl)s3)sc2C1 +Cn1c(S(=O)(=O)c2ccccc2F)c(S(=O)(=O)N2CCC(CNS(=O)(=O)C(F)(F)F)CC2)c2ccccc21 +Cc1nc(-c2ccc(N3CCN(C)CC3)cc2)nc(NCCN2CCOCC2)c1C +CN1C(=O)C(CN2CCCCC2)CC1c1ccc(C2CCCC2)cc1 +CC1CN(c2ncc(C(=O)O)cc2Cl)CCN1c1nc2c(-c3cc(F)c(F)c(F)c3)cc(C(F)(F)F)cc2[nH]1 +COc1ccc2oc(C(=O)N(C)c3ccc(OC)nc3)cc2c1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCC23COC3)cn1 +N#Cc1ccc(C2(C(N)=O)CC3CCC(C2)N3C(c2ccccc2Cl)c2ccccc2Cl)nc1 +CC1CCCN1CCCOc1ccc(C(CN2CCCCC2=O)=NOC(C)(C)C)cc1 +Cc1cc2c(nn1)-c1cc(OCc3ccccc3)ccc1C2=O +CC(C)C(NC(=O)C(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCc1ccccc1 +COC(=O)CC(C(=O)OC)=C(CCCCCCCCCCCCCCCCOS(=O)(=O)O)C(=O)OC +Cc1oc(-c2ccccc2)nc1CCOc1ccc2c(c1)C(C)(C)CC2CC(=O)O 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+COc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(CC(N)=O)CC2)c(=O)n4C)cn1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(F)c1O +Nc1ncc(-c2ncccc2OC(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)CC1 +NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1 +CC(C)N1Cc2cc(OCc3cccc(-c4ccc(Cl)c(C(=O)O)c4)c3)ccc2C1=O +CCCc1sc(-c2ccc(OC)c(OCCO)c2)nc1CSc1nccc(N)n1 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN2CCSC2)cc1 +CN1CCN(C(=O)CNC2CC2c2ccc(-c3ccc(F)cc3)cc2)CC1 +O=C(C=Cc1cccnc1)Nc1ccc(C(=O)NCC(F)(F)F)cc1 +CCCCn1cc2c(nc(NC(=O)Cc3cccs3)n3nc(-c4ccco4)nc23)n1 +CNC(=N)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(c1ccccn1)C1CC1)CC2 +Cc1nc2c(s1)C(C(=O)NCc1ccc(Cl)cc1Cl)CCC2 +N=C(N)c1ccc(-c2cc(-c3cccc(C(=N)N)c3[N+](=O)[O-])no2)cc1 +O=C1C2C3C=CC(C4CC34)C2C(=O)N1CCCCN1CCN(c2cccc(Cl)c2)CC1 +CCCCCCCCCCc1ccc(NC(=O)C(N)CC(F)OP(=O)(O)O)cc1 +NC(=O)C1CCCN1c1nc(Nc2ncc(Cc3ccccc3)s2)cc(C(F)(F)c2ccc(F)cc2)n1 +C=C1C(=O)C23C(=O)OC4CCC(C)(C)C5C(=O)OCC45C2CCC1C3OC(C)=O +COc1cc2c(c(OC)c1OC)-c1cc3cc(C(C)O)oc3cc1C(O)CC2 +COc1cc2nc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nnc2cc1-c1cccc(O)c1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2[nH]cnc2c1 +CC1(c2nc3c(C(N)=O)cccc3[nH]2)CCCN1 +CCN(CC)CCOc1ccc(NC(=O)Nc2ccc(F)cc2F)cc1 +CCN(CC)C(=O)N(CC)c1cnc(N(CC)CC)nc1NC(Cc1ccc(OC(=O)N2CCCC2)cc1)C(=O)O +c1cc(CNCC2CCN(CCc3c[nH]c4ccc(-n5cnnc5)cc34)C2)co1 +CN(C)C(=O)NCCCCN(Cc1nccc2c1[nH]c1ccccc12)C1CCCc2cccnc21 +O=C(CCN1CCC(c2nc(-c3ccccn3)no2)CC1)NC(c1ccccc1)c1ccc(Cl)cc1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)nc3cc(CN(C)C(C)C)ccn23)n1)c1ccccc1 +COc1cccc(Oc2cc(N3CCC(Oc4ncc(F)c(N)n4)CC3)ncn2)c1 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=S)Nc1ccc(C#N)cc1)CC2 +COc1cc2cc(C(=O)Nc3ccc4c(c3)OCCO4)[nH]c2cc1OC +CCNC(=O)c1ccc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4ccccc4OC)cc32)cc1C +NC(=O)c1ccccc1OCCCN1CCN(c2cccc3c2ccn3Cc2ccccc2)CC1 +CC(C)(C)c1ccc(CCN2CCc3cc(S(=O)(=O)Nc4ccc(OCCCC5CCCCC5)cc4F)ccc3C2)cc1 +COC(=O)N1CCC(CN(C2Cc3cc(C#N)ccc3N(Cc3cncn3C)C2)S(=O)(=O)c2ccccn2)CC1 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+CCOc1ccccc1-c1ccc(-c2nc3ccc(F)cc3c(NCCCC(=O)O)c2C#N)c(C)c1 +Nc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O +COc1ccccc1CNCCCCCCNCCCCCCCCCCCCCCNCCCCCCNCc1ccccc1C +COc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1N(C)C1CCNCC1 +COc1ccc2[nH]cc(C3(CNC(=O)C4CC4)CCC3)c2c1 +CC(=O)OCCNc1c(C(=O)NCc2ccc(F)cc2F)c(=O)n(O)c2ncccc12 +O=C(NCC1OC(=O)N2c3ccc(N4CCOCC4=O)cc3OCC12)Nc1ccc(Cl)cc1 +CC(C)C(CO)NCc1nc(-c2cccc(N3CCOCC3)c2)ccc1F +CCSCc1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 +CC1=C(N2CCC3(CCN(C(C)(C)C(O)c4ccc5c(c4C)COC5=O)CC3)C2=O)COC1=O +CN(CC#N)C(=O)C(N)C12CC3CC(O)(CC(O)(C3)C1)C2 +COC(=O)c1ccccc1CCc1c(C(=O)O)[nH]c(=O)[nH]c1=O +COc1ccc(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)C(CCCCNC(=O)c2ccccc2)C(=O)NO)cc1 +O=C(NCCCCN1CCN(c2cnc3ccccc3c2)CC1)c1ccccc1 +CCc1ccc(-c2c(-c3cnc(C)[nH]3)c(=O)[nH]c3ccc(C#N)cc23)cc1 +CCCN(CCC)C(=O)c1cc(C)cc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2NCCNC2=O)c1 +Cc1nc(-c2ccc(Cl)cn2)nc(NCC(NCCCCc2ccc(O)cc2)c2ccccc2)c1Cl +CC(C)(C)C(O)C(=O)N1CC(c2cc(F)ccc2F)=CC1c1cccc(O)c1 +Nc1nc(O)c2ncn(CC3(OCP(=O)(O)O)CC3)c2n1 +CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(-c4ccc5cn[nH]c5c4)c[nH]c3n2)c(OC)c1 +COc1ccc2c(c1)c(CCN)cn2S(=O)(=O)c1ccccc1 +CC(Cc1c[nH]c2c(OC(C)C)cccc12)NCC(O)c1cccc(Cl)c1 +O=C1C(=CC=Cc2ccccc2)COc2ccc(Cl)cc21 +CC1(C)CC(NC(=O)c2cccc3[nH]ncc23)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 +CC(C)n1cc(Nc2ncc(C3CC3)c(NCCCNC(=O)C3CCC3)n2)cn1 +COC1CC(COC2CCC(C(=O)O)CC2)N(C(=O)Cc2cc(Cl)c(NC(=O)c3cn(C)c4ccccc34)cc2Cl)C1 +COc1cc(CN2N=C(c3ccc(OC)c(OC)c3)C3CCCCC3C2=O)cc(OC)c1 +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2ccc(C#N)cc2)cn1C(C)C +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2ccc(C(=O)O)cc2)C(C(=O)O)C1 +O=C(O)CC(NC(=O)CCCCc1ccc2c(n1)NCCC2)c1ccc(Cl)c(Cl)c1 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)C2)CCN1Cc1ccc(F)cc1 +CCOC1CN(c2cccc(-c3cccc(Cl)c3OCc3cc(C)c4c(c3)CCN(C3CCOCC3)C4)n2)CCC1C(=O)O +CNC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3cnn(C4CCN(C(=O)OC(C)C)CC4)c3n2)cc1 +CC1CN(c2ncc(C(N)=O)cc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +O=C(CCC(=O)c1ccccc1)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +COc1cccc(NC(=O)c2cc(Cl)cc(Oc3cncnc3)c2)n1 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+COc1cccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc(Br)c2OCC(=O)O)c1 +CN(C)c1ccc(C(=O)c2ccc(N(C)C)c3ccccc23)cc1 +Cc1nc(C2(c3cnn(C)c3)NC(c3nc(-c4ccccn4)c[nH]3)Cc3c2[nH]c2ccccc32)no1 +COC1CCCN(c2nc3c(c(Nc4ccc(C(F)(F)F)cc4)n2)CCN(c2ncccc2C(F)(F)F)CC3)C1 +COc1ccc(CCCCNCCOc2cc(F)cc3c2OCC=C3)cc1 +O=C1OC(c2ccc(F)c(F)c2)=NC1=Cc1cccnc1 +Cc1nc2ccc(Oc3ccc(Cl)cc3F)nc2c(=O)n1CC1CCCN(C(C)C)C1 +Cc1c(F)c(Oc2cccc(C(=N)N)c2)nc(N2CCN(C3CCCCC3)CC2)c1F +Cc1ccc(NC(=Nc2nc3nn(C)cc3c3nc(-c4ccco4)nn23)Nc2ccc(C)cc2)cc1 +CC(C)CNCc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +Cc1ccc(CNC(=O)Nc2ccc(OS(N)(=O)=O)cc2)cc1 +NC1=Nc2ccc(Oc3ccccc3)cc2CN1C(COC(=O)NC1CCCCC1)C1CCCCC1 +Cc1ncc(-c2cnc(Nc3cc(N4CCNCC4)ccn3)s2)cn1 +COc1ccc(-c2n[nH]c3cc(NC(=O)NCc4ccc(F)cc4)ncc23)cc1 +COc1ccc(Br)cc1CCc1c(F)cccc1C1=NCCN1 +COc1ccc(NC(=O)CN2CCN(c3nnc(Cc4ccncc4)c4ccccc34)CC2)cc1OC +CC1(c2ccc(OCCN3CCCC3)cc2)c2ccc(O)cc2CCN1c1cccc(O)c1 +N#Cc1cn(-c2cc(C(=O)O)ccn2)cc1C1=CCCCC1 +O=C(Nc1cccnc1)c1ccc(CNS(=O)(=O)c2ccccc2)cc1 +CC(C)n1cc(-c2n[nH]c3ccnc(OC4CCOC4)c23)cn1 +O=C1COc2ccc(CNC3CCN(CCN4C(=O)COc5ccc(Cl)cc54)CC3)nc2N1 +NCCCCN(Cc1nccc2c3ccccc3n(CCN3CCNCC3)c12)C1CCCc2cccnc21 +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(NC(=O)Nc3ccncc3)CCc3ccccc32)c1 +O=C(NC1CCC(CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1)c1ccsc1 +Cc1nc(-c2ccccc2F)c2c(N3CCc4cnn(C5CC5)c4C3)ncnn12 +O=C(NCC1CCNCC1)C1C(C(=O)Nc2ncc(Br)s2)C2C=CC1C21CC1 +CC(C)(C)CC(=O)NC(Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1Cc1ccccc1 +O=C(Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1)Nc1nnc(C2CCCO2)s1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(C#Cc3ccc(CO)cn3)CCC2C)c1 +Fc1ccc(-c2csc3ncnc(N4CCC(COCCN5CCCC5)CC4)c23)cc1 +O=C(NCCn1ccnc1)c1cc(N2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-] +CC(=O)c1cn(CC(=O)N2CC(F)CC2C(=O)NCc2cccc(Cl)c2F)c2cc(OCc3ccccc3)ccc12 +Cc1cc2c(OCC(O)CN3CCC(c4cccc5sccc45)CC3C)cccc2[nH]1 +CC1(C)C2CC=C(CN3CCC(NC(=O)Nc4cc(F)cc(C(F)(F)F)c4)CC3)C1C2 +CCN(CCCCNc1c2c(nc3ccccc13)CCCC2)CCC(=O)Nc1nc(-c2ccc(OC)cc2)cs1 +CCCc1c(C)nc(N2C(=O)CSC2c2c(F)cccc2Cl)nc1C +O=C(Nc1cccc(Oc2ccc3c(C=Cc4ccccc4)n[nH]c3c2)c1)c1ccccc1 +CCn1c2c(c(=O)[nH]c1=O)C(c1ccc(C)cc1)C1=C(CN(Cc3ccccc3)C1=O)N2 +CC(NC(=O)Nc1cc2[nH]nc(NC3CCOC3)c2cn1)c1ccccc1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccc(OCCCO)cc1 +COc1cc(-c2nc3cc(C=CC(=O)NO)ccc3n2CCCO)ccc1OCc1ccccc1 +COc1ccc(-n2cc3c(n2)c(N)nc2ccccc23)cc1 +Cc1c(COc2ccc(Cl)cc2)oc2cccc(OCCNCc3cccnc3)c12 +C=CC1(C(N)C(=O)N2C(C#N)CC3CC32)CCCCC1 +COc1ccc(-n2nc(C)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c(CN)c1 +O=C1OCC2C1Cc1c(F)cccc1C2C=Cc1ccc(-c2cccc(C(F)(F)F)c2)cn1 +COc1cc(OCc2cccc(-c3ccc(O)cn3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +COc1cc(C(F)(F)F)ccc1-c1ccnc2cc(S(=O)(=O)Nc3nccs3)c(F)cc12 +O=C(OC(C(=O)O)C(OC(=O)c1cc(O)c(O)c(O)c1)C(=O)O)c1cc(O)c(O)c(O)c1 +CC1CS(=O)(=O)CCC1N=Nc1ccc([N+](=O)[O-])o1 +Cc1nc2ccc(CN(CCO)c3ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 +COc1cc(O)ccc1-c1ccc2c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)n[nH]c2c1 +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ncco3)cc2N=C(N)C1 +Oc1ncn(-c2ccc(-c3cnc(N4CCOCC4)c4nc(C=Cc5ccc6ccccc6n5)cn34)cc2)n1 +COc1ccc(Cc2cc3ccccc3s2)cc1C1OC(CO)C(O)C(O)C1O +N#CC(=C(N)Sc1ccccc1N)c1cccc(C(O)c2cccc3ccccc23)c1 +CC(C)N1CCN(C(=O)COc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +CCCN(C)c1ncc(Cl)c(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)n1 +O=C(CCCCCNc1c2c(nc3ccccc13)CCCC2)NCCc1c[nH]c2ccc(O)cc12 +CC(C)NC(=O)CN1CCN(CCc2ccc(-c3cccc(N)n3)cc2)CC1 +COc1cc2c(cc1OC)C(=O)N1C=C(c3ccc(OCCCN(C)C)cn3)CC1C=N2 +CCCN(C)Cc1sc(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(CC)c3)no2)cc1CC +CCc1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1 +CC(=O)SCC(C)C(=O)N(CC(=O)O)C1CCCCCC1 +CC1=C(C(=O)OC(C)C)C(c2ccccc2C(F)(F)F)N(C(=O)OC2CCN(Cc3ccccc3)CC2)C(=O)N1 +CCN(CC)C1CCN(C(=O)c2cccc(Nc3nc4nc5c(cnn35)CCCCC(=O)Nc3cccc(c3)N4)c2)C1 +CC(C)N1CCC(Oc2ccc3cc(C(=O)N4CCOCC4)ccc3c2)CC1 +CCN(CC)CCN(C(=O)CCS(=O)(=O)c1ccccc1)c1nc2cc3c(cc2s1)OCO3 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(SCc2ccccc2B(O)O)nc1 +NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3nn[nH]c3n2)cc1 +O=C(O)c1ccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)cc1 +COCc1cc(OC)c(-c2csc3c(N(C4CCC4)C4CCOC4)c(OC)nn23)c(OC)c1 +COc1ccc2c(c1)C1CN(C)C2Cc2ccc(Br)cc21 +Clc1ccc2c(NCCCNCCNc3ccnc4cc(Cl)ccc34)ccnc2c1 +CC(CC1CCC2C3CC(=O)C4=CC(=O)CCC4(C)C3CCC12C)=NO +Cc1c(C2CC2)nc2ccc(NC(=O)c3ncc(-c4ccc(F)nc4)cn3)cn12 +CC(C)NCc1c(C(=O)NC2CCCC(O)C2)noc1-c1ccc(C(F)(F)F)cc1 +Cc1ccccc1S(=O)(=O)N1CCC(N(Cc2ccc3ccc(C(=N)N)cc3c2)S(C)(=O)=O)CC1 +CC(C)n1c(=O)n(C(=O)NC2CC3CCC(C2)N3C)c2ccccc21 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC1COCC1=O +CSc1nc2cc(Cl)c(Oc3cccc(Cl)c3Cl)cc2[nH]1 +O=C(c1cccc(F)c1-n1nccn1)N1C2CCC1C(Nc1cnc(C(F)(F)F)cn1)C2 +CC(C)(COc1ccc(-c2ccc(-c3ncc(C(C)(C)C)[nH]3)cn2)cc1)C(=O)O +COc1ccccc1-n1cc2nc(-c3ccc(C)o3)nc(N)c2n1 +N#Cc1c[nH]c(C(=O)Nc2ccc(C3CCN(C(=O)CCN4CCOCC4)CC3)cc2C2=CCCCC2)n1 +NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccccc4)cc3)c2)c1 +CCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(-n5cnc(C)n5)ccn34)c12 +CC(C)(O)CSc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br +CC(C)N(CCN1CCC(c2noc3cc(F)ccc23)CC1)C(=O)c1noc2ccccc12 +CC1CCN(C(=O)CSc2nc(NCc3ccccc3)c3ccccc3n2)CC1 +Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC2CC2)nc1 +CCCCc1nc(Cl)c(CO)n1Cc1cccc(Oc2ccccc2C(=O)O)c1 +CC1CCCCN1CCCNC(=O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)C2=O +CCCOCCn1c(=O)nc(NC2CCC(O)CC2)c2ncc(-c3ccc(OC)nc3)cc21 +OC1C(O)C(n2cnc3c(NC4CC5CCC4C5)nc(Cl)nc32)C2CC12 +CS(=O)(=O)c1ccc(N2CCC(C3CCN(c4ccccn4)CC3)CC2)cc1 +N#CC(Cc1ccc(-c2csc(C(=O)N3CCN4CCOCC4C3)c2)cc1F)NC(=O)C1NC2CCC1C2 +COc1ccc(C2(O)OC(=O)C(c3cccc(OC)c3)=C2Cc2ccccc2)cc1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2F)nc1-c1cc(F)ccc1C +CN1CC(c2ccc(N=Nc3ccccc3)cc2)CCC1=O +c1coc(CNc2ncnc3ccc(-c4ccc5c(c4)OCO5)cc23)c1 +Cc1ccc(Nc2nccc(N3CCN(c4ccnc5cc(Cl)ccc45)CC3)n2)cc1 +CCC(C)C(N)CN(C(=O)C1CC1c1nc(C)cs1)c1ccc(-c2ccccc2)cc1 +COc1cc2ncnc(N3CCN(C(S)=Nc4cncc(Cl)c4)CC3)c2cc1OC +O=C(NC1CCC(O)C1)c1noc(-c2ccc(F)cc2)c1Cl +c1ccc(C(c2ccccc2)C2CCC3CN2CCN3c2ccc3ccccc3c2)cc1 +CCc1ncnc(NC(C)c2ccc(OC(=O)NCCCNC(C)=O)cc2)c1Cl +Cc1nc2ccc(Oc3ccc(-c4ccccc4)cc3)nc2c(=O)n1CC1CCCN(C(C)C)C1 +CC(=O)N1Cc2cc(C#N)ccc2N(Cc2c[nH]cn2)CC1Cc1ccccc1 +CC1CC=C(C(=O)O)C(C)(c2ccc(Cl)c(Cl)c2)C1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)C1CCC(C(F)(F)F)CC1 +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(C(=O)N2CCCCC2)CN1 +COc1ccc(S(=O)(=O)N(CC(=O)NO)Cc2cccc(C(=O)O)c2)cc1 +CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2c(C)cccc12 +CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)C(=O)CC2)cc1 +COCCn1c(=O)cnn(-c2ccc(Cl)c(C(=O)NCC3(O)CCCCCC3)c2)c1=O +CC(Nc1cccc(F)c1F)c1cc(C(=O)N(C)C)cn2c(=O)cc(N3CCOCC3)nc12 +COC(C)(C)COc1ncnc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c1Cl +Cc1nc2cnc3cc(F)c(-c4ccc(Oc5ncccn5)cc4Cl)cc3c2n1C1CCS(=O)(=O)CC1 +CC1Cn2c(nnc2-c2cnccn2)C(=O)N1Cc1ccccc1OC(F)(F)F +CC(Cc1cc(F)ccc1F)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(CCN(C)C)C3 +COc1cc2nc(-c3ccc(C)cc3)cc(O)c2cc1-c1cnco1 +COC1Cc2sc(C(=O)c3ccccc3)cc2C2(CCN(Cc3ccccc3)CC2)O1 +C=CCOc1ccc(C=CC(=O)N2CC3CC34C2=CC(=O)c2[nH]c(C)c(C(=O)OC)c24)cc1 +CCOC(=O)c1c(CC)[nH]c2ccc3c(c12)CN1CCc2cc(OC)ccc2C1O3 +CC(C)(CC(=O)N1CCCCC1)NCC(=O)N1CC(F)CC1C#N +O=C(Nc1ccncn1)c1cc2c(OCCC3CCCCN3)c(-c3ccc4c(c3)CCC4)c(O)nc2cc1Cl +COc1ccccc1C(=O)C=C1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 +O=C(NCC=CCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2 +Cc1nn(C2CCS(=O)(=O)C2)c(C)c1CN(C)C(=O)C=Cc1sc2ccccc2c1Cl +CC(C)(C)COc1ccc2c(c1)C1(COC(N)=N1)c1cc(-c3cncc(F)c3)ccc1O2 +Cc1cccc2[nH]c(C3C4CC4CN3C(=O)COc3ccc(-c4ccccc4)cc3)nc12 +Cc1cc(N2CC3CN(C(=O)c4cc(F)ccc4-c4ncccn4)CC3C2)nc(C(F)(F)F)n1 +CN1CCCC1CCOCC1CCN(c2nc(N3CCC(C(N)=O)C3)nc3scc(-c4ccccc4)c23)CC1 +OC(CCN1CC=C(Cc2ccccc2)CC1)c1cc2ccccc2s1 +O=C1NC(N2CCCCC2)=NC1=Cc1c[nH]c2ncccc12 +Cc1cc(-c2cnn(C(CO)(CO)CO)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +COc1cc(CCNCC(O)c2ccc(O)c3[nH]c(=O)ccc23)ccc1OCCCc1ccccc1 +CC(c1ccc(-c2ccn(C)c(=O)c2)cc1)N1CCC(CC(C)(C)O)(c2cccc(F)c2)OC1=O +O=C(O)c1ccc2c(c1)nc(NCCCc1ccccc1)c1ccncc12 +O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1ccc(OC(F)(F)F)cc1 +CCCCN(CCc1ccncc1)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)nn(C)c12 +CC(C)Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCC(C)(C)N4CCCC4)cc3)oc2c1 +CCN(CC)C(=O)CCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +Cc1cc(C#N)ccc1N1CCc2c(-n3ccc(-c4nccs4)n3)ccnc21 +Cc1ccc2c(c1)c(C(F)(F)F)c1n2CC(NC(=O)c2c(Cl)cc(-n3cnnc3)cc2Cl)(c2ccccc2)CC1 +CN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(Cc2nc3cc(F)ccc3s2)CC1F +Cc1ccc2c(c1)c(-c1cc(C)nc3ccccc13)c(C)n2CC(=O)O +CCOC(Cc1ccc2c(ccn2Cc2nc(-c3ccc(F)cc3)oc2C)c1)C(=O)O +Cc1ccc(C(CN)C(=O)Nc2ccc3cnccc3c2)cc1 +CC(NNC(=S)c1ccc(C(=O)O)cc1)=C1C(=O)N(c2ccc(C)c(C)c2)c2ccccc21 +CN(Cc1ccc(F)cc1)C(=O)C1(c2ccc(Cl)c(Cl)c2)CC1CN1CCN(C(=O)CN2CCCC2)CC1 +CC(=O)NC1CCC(CCN2CCN(c3ncc(C)c4occc34)CC2)CC1 +Cc1ccccc1-c1[nH]c2ccccc2c1CC(=O)N(Cc1ccncc1)C(C)C +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccc1C(F)(F)F)CC2 +O=C(Nc1cccc(-c2cn[nH]c2)c1)C(Cc1ccccc1)NCc1cscn1 +CC1CCC(C(=O)N(c2ccc(Oc3ccccc3Br)cc2C(=O)O)C(C)C)CC1 +O=C(N1CCc2cnc(NC3CCOCC3)nc2C1)N1CCCC1c1ccccn1 +CN(C)CCN1C(=O)c2cccc3cc4ccc(N)cc4c(c23)C1=O +COC(=O)CC(NC(=O)c1ccc(-c2cn[nH]c2)c(C)c1)c1ccccc1 +COc1ccc(-c2ccc3ncc4nnn(C(C)c5ccc(F)cc5)c4c3c2)cc1 +CC1CC1c1nc(-c2cnc(N)c(OC(F)F)c2)cc(N2CC3CC2CO3)n1 +Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1 +CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]c(=NC(=O)c1ccc(-c3ccccc3)s1)n2CCC(N)=O +CCCn1nc(-c2ccc(OCCCN3CCC(C)CC3)cc2)c2sccc2c1=O +CC(=O)Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2C(C)(C)C +O=C(Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)c1ccco1 +Cc1ncccc1Oc1ccc(NC(=O)N2CCc3ccccc32)cn1 +CC(C)c1nnc2ccc(-c3ocnc3-c3ccccc3Cl)cn12 +Cn1cc(-c2ccc3cnc(Nc4ccc(-n5cnc(N6CCOCC6)n5)cc4)nc3c2-c2ccccc2)cn1 +Cc1cc(F)ccc1C(O)(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)c1ccc(F)cc1C +Cc1ncnc(-c2ccc(C(=O)N3CCN(c4ccccc4)CC3)cc2)c1C#Cc1ccc(N)nc1 +O=C(O)C(CC(=O)C1(S)CCCCC1)Cc1ccc(-c2ccccc2)cc1 +NC(Cc1c[nH]c2ccccc12)C(=O)N1Cc2ccccc2CC1C(=O)O +O=C(NC1CCCC(O)(Cc2ccccc2F)C1)c1ccc2[nH]nc(-c3ccc4nccn4c3)c2c1 +COc1cc(CN(C)c2cnc3nc(N)nc(N)c3c2)cc(OC)c1 +COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1OC +C=C(C)C1CC=C(C(=O)NCc2ccc(O)c(OC)c2)CC1 +Cc1ccc(-c2cc(C(=O)NCc3cnc(C)cn3)cc(-n3c(=O)oc4ccccc43)c2)cc1 +CCN(c1ccc(C(C)C)c(OCC=C(C)C)c1)c1ccc(C(=O)O)cn1 +CN(C)c1ccncc1-c1ccc(-c2csc(NC(=O)C3CC3)n2)cc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCN(Cc3cnc(Cl)s3)CC2)c2ccc(C)c(Cl)c2)CC1 +CCCN(CC=CC(C)=CC(=O)O)c1cc(C(C)(C)C)cc2c1CCC2(C)C +Clc1ccc2c(NCCCCCNc3ccnc4cc(Cl)ccc34)ccnc2c1 +Oc1ccc2c(c1)CCN(c1ccccc1)C2Cc1ccccc1 +O=C(O)CCc1ccccc1-c1cccc(-c2ccccc2OCc2c(Cl)cccc2Cl)c1 +O=C(Nc1cccc(C(F)(F)F)c1)N1CCN(CC2CCCN(C3CC3)C2)CC1 +Oc1nc2ccc(N3CC4CC3CN4)nc2c2ccccc12 +COc1cccc(O)c1C(=O)c1c(O)cc(C(=O)OC2CCCNCC2NC(=O)c2ccc(O)cc2)cc1O +CCOC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c(N)scc12 +COc1ccc(CC2(C(=O)NC(Cc3ccc(NC(=O)c4c(Cl)cccc4Cl)cc3)C(=O)O)CCCCC2)cc1 +CN1CCC(n2cc(S(=O)(=O)c3cccc4ccccc34)c3ccccc32)C1 +CCc1c(-c2ccccc2)oc(-c2ccc(O)cc2)c1-c1ccc(OCCN2CCCCC2)cc1 +COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCOCC4)c(OC)cc23)c(C)cc1Cl +CC(C)C1NC(=O)C(Cc2cccc(Cl)c2)NCCOc2ccccc2CCCNC(=O)C(CNC2=NCCCN2)NC1=O +CCCS(=O)(=O)N1CCC(CNC(=O)c2c(Cl)cccc2Cl)(c2ccccn2)CC1 +CN1CCC2(c3cccc(O)c3)CC(c3ccccc3)CC1C2 +NS(=O)(=O)c1ccc(N2N=C(C(F)(F)F)CC2c2cccc3c2OCO3)cc1 +CCOC(=O)N1C(=S)N=C(C)C(=C(O)OCC)C1c1cccc(Cl)c1 +NC1CN(c2cccnc2)CCC1c1cc(F)c(F)cc1F +Cn1nccc1-c1cc(Cl)ccc1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1F +COc1cccc(-n2ccc3c(sc4nccc(OC)c43)c2=O)c1 +COc1ccc(-n2cc(-c3ccc(S(N)(=O)=O)s3)nn2)cc1Cl +O=C(Cc1cc(F)cc(F)c1)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CNC(=O)C(NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(C)(C)C +Cn1cncc1C(OCc1cn(Cc2cccnc2Br)c(=O)cc1-c1cccc(Cl)c1)c1ccc(C#N)cc1 +Cc1cc(C(=O)O)ccc1-c1ccc(N2C(=O)N(c3cnccn3)C3(CCN(Cc4ncccc4C)CC3)C2=O)cc1 +Cn1c(=O)c2c(ncn2CCCN2CCc3ccccc3C2)n(C)c1=O +COc1ccc(-c2coc3ccc(-c4nnc(SCc5cccc(C(F)(F)F)c5)o4)cc23)cc1 +O=C(NCc1ccncc1)c1ccccc1N1CCCN(C(=O)Cc2ccc(F)c(F)c2)CC1 +CCOc1cc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc(S(C)(=O)=O)c1 +Cc1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1Cl)=[N+]([O-])C2 +O=C(NCCC=Cc1ccccc1)c1ccccc1CN1CCc2ccc(O)cc2CC1 +CCc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1[nH]c(COC)nc1C +COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)nc3)c2cc1OC +CC(C)C(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 +Cc1cccc(NC(=O)c2cc(O)c3cccc(NS(C)(=O)=O)c3n2)c1 +c1cc2c(-c3ccnc4[nH]ccc34)c[nH]c2cn1 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+O=C1c2ccc(COc3cccc(F)c3)nc2CCN1c1ccc(F)cn1 +Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)cc(F)cc2F)cn1 +CCC(=O)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +CCC(CO)c1cc(Cl)c2c(c1Cl)C(=O)N(Cc1c(C)cc(C)[nH]c1=O)CC2 +CC1=CC(C)(C)Nc2ccc(-c3ccc(C#N)s3)cc21 +CC=CC(OC)C1CCC(C)C(O)(C(=O)C(=O)N2CCCCC2C(=O)OCc2ccccc2)C1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)C(=O)NCc1ccccc1 +CCOC(=O)c1nnn2c1nc(N1CCOCC1)c1sccc12 +CCCCCC(O)C=CC1CCC(=O)N1CCc1ccc(C(=O)O)cc1 +CC(C)(C=NOCC(=O)O)Cc1c(SC(C)(C)C)c2cc(OCc3ccccn3)ccc2n1Cc1ccc(Cl)cc1 +COc1cc2cc(C(=O)CC(O)C3CC[N+](C)(Cc4ccccc4)CC3)sc2cc1OC +COc1ccc(-c2cn3c(O)nc4c(c3n2)CN(Cc2ccccc2)CC4)c(F)c1 +CC1CCN(C)C1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +CC#CC(CC(=O)O)c1ccc(OCc2cccc(OC)c2)cc1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3cccc(C)n3)n1)C(C)(C)CN2 +COc1ccc(-c2cc(O)n(-c3nc(C(=O)O)cs3)n2)cc1 +CN1C(=O)C(=Cc2ccccc2F)Sc2ccc(C(=O)NC3CCN(Cc4ccccc4)CC3)cc21 +CN1CCN(C(=O)c2cc(Nc3ncc4cc(-c5cnco5)n(C5CCCC5)c4n3)cn2C)CC1 +COc1ccc(C2CN(C)Cc3cc(OCCCN4CCN(C(C)=O)CC4)ccc32)cc1 +Cc1cc2cccc(C)c2nc1N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(C(=O)O)cc1 +O=c1c2occc2ccn1C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O +C=CCCC(CC1OC(=O)C1CCCCCC)OC(=O)CNC=O +Cc1cccc(-c2nn3c(c2-c2ccnc4ccc(OC(F)(F)F)cc24)CCC3)n1 +Cc1nccc(-c2cn(Cc3ccccc3)c3cnccc23)n1 +O=C1CCCC2=C1C(c1ccc(F)c(Br)c1)C1=C(O)CNCC1=N2 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)c3ccco3)c2cn1)c1ccccc1 +C#CCCCCOc1ccc2oc(=O)c(NC(C)=O)cc2c1 +CCC(NC(=O)C(C)NC(=O)C(C)CC(O)C(CC(C)C)NC(=O)C(NC(=O)CC(C)C)C(C)C)C(=O)O +CN1CCC23Cc4nc5cccc([N+](=O)[O-])c5cc4CC2(O)C1Cc1ccc(O)cc13 +CC1(C)CC(NC(=O)c2ccc(Oc3cccc(-c4cn[nH]c4)c3C#N)c(Cl)c2)CC(C)(C)N1 +CC(C(=O)Nc1ccc(C2CCCNC2)cc1)c1cccc(C(F)(F)F)c1 +CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)C2=O)c(F)c1 +Cn1cc(-c2cc(S(=O)(=O)c3ccccc3)ccc2OCC2CC2)c2cc[nH]c2c1=O +CCNC(=O)Nc1ccc(-c2nc(N3CCOCC3CC)c3c(ccn3C)n2)cc1 +COC(=O)c1ccc(NC2c3cc4c(cc3C(c3cc(OC)c(O)c(OC)c3)C3C(=O)OCC23)OCO4)cc1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2C(=O)N(C)C3)n1 +CCOC(=O)C=CC(=O)N(CC(N)=O)NC(=O)C(C)NC(=O)C(C)NC(=O)CCCCC1SCC2NC(=O)NC21 +CC1Cn2c(nnc2-c2cc(F)ccn2)CN1C(=O)c1cccc(Cl)c1Cl +C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4c(F)cccc34)n2)c(OC)cc1N(C)CC[N+](C)(C)[O-] +O=S(=O)(Nc1cc(-c2cnc3ccc(Cl)nn23)cnc1Cl)c1ccc(F)cc1 +CC(Nc1nc(N)nc(N)c1Cl)c1nc2cccc(Cl)c2c(=O)n1-c1cncc(F)c1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCc1cnnn1-c1ccccc1 +Cn1ncc(C(=O)N2CCC2)c1C(=O)NCCc1nc(-c2ccccc2)nn1Cc1ccccc1 +CCCCC(NC(=O)CCc1ccccc1)C(=O)NC(CCS)C(=O)O +CC(CN)(Cc1cccc(C(F)(F)F)c1)c1nnn[nH]1 +O=C(Nc1ccc(-c2nnc(-c3ccccc3)o2)cc1)c1ccccc1Cl +Cc1cc(C)c(CN2CCc3ccc(OC(C)C)c(Cl)c3C2=O)c(=O)[nH]1 +COC1CCC2(CC1)Cc1ccc(Br)cc1C21N=C(N)c2ccccc21 +O=C(NCc1c(-c2ncco2)n(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(N2CCCCC2)nc1 +Nc1ccc(C(=O)NCCCCN2CCN(c3nsc4ccccc34)CC2)cc1 +c1ccc(CC2CCN(CCSc3nc4ccc[nH]c-4n3)CC2)cc1 +CC(C)(C)c1cc(C(=O)C=CCC2CC2)cc2c1OCC2(C)C +Cc1c(O)nc(SCc2cccc(C#N)c2)nc1Cc1c(Cl)cccc1Cl +CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(Cl)cc3)CC2C)c(=O)c1=O +c1ccc(CN2CCN(CC3COC(c4ccccc4)(c4ccccc4)S3)CC2)cc1 +COCCN1CC(c2cccc(F)c2F)CCC(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)C1=O +CC1CCCN1C1CCN(c2ccc(N3CCC4(CCN(CC5CC5)CC4)C3=O)c(C(F)(F)F)c2)C1 +COc1ccccc1CCN(C(=O)c1ccc(CN2CCCC(c3ccccc3C)C2)cc1)C1CCNC1 +O=C1c2c(cc(N3CCOCC3)nc2-c2ccccc2)OCCCN1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ncc(N)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +c1ccc2c(c1)C(=C1CN3CCC1CC3)c1ccccc1-2 +CCCCC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cc1 +CCCC(CCC)n1ccc2cc(C(=CC(=O)Nc3ccccc3OCCCC(=O)O)CC)ccc21 +CCOC(=O)Nc1cc(CO)cc(Nc2c3ccccc3nc3c(OC)cccc23)c1 +OC1COC(n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)C1O +CN1CC=C(c2c[nH]c3ccc(OCc4ccccc4)cc23)CC1 +Cc1ccnc(N2CCN(CCc3c(C)n4c5c(cc(C(=O)C(C)C)cc35)CCC4)CC2)c1 +O=C(CCCCCCNc1nc(N2CCOCC2)nc2[nH]cnc12)NO +CCCCCC=C(c1cc(Br)c(OC)c(C(=O)OC)c1)c1cc(Br)c(OC)c(C(=O)OC)c1 +O=C(O)COc1cccc(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)c1 +Cc1nc(N)ccc1CNC(=O)Cc1c(Cl)ccc(NCC(F)(F)c2ccccc2)c1F +CCN1c2ncc(CCOc3ccc(C(=O)O)cc3C)cc2C(=O)N(C)c2ccc(OC)nc21 +O=C1COc2c(cccc2N2CCN(CCCc3c[nH]c4ccccc34)CC2)N1 +COc1ccc(-c2cc(C3=Nc4c(C(C)(C)C)nn(CCCO)c4C(=O)NC3)ccc2OC)cn1 +Cc1cc(F)ccc1C(=O)N1CCn2c(nnc2-c2cnccn2)C1 +CC(C)CCCOc1ccc2c(c1)Nc1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn1CC2 +CCCCc1c(C)sc2nc(-c3ccc(O)c(O)c3)[nH]c(=O)c12 +CCNC(=O)Nc1nc2cc(NCCCCN(CC)CC)ncc2cc1-c1cc(OC)cc(OC)c1 +O=C(c1ccc2ccccc2c1)N(CCN1CC=C(c2ccccc2)CC1)c1ccccn1 +O=C(NC1CCCNC1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +CCCC(=O)NCCc1nc(-c2nc(C)cs2)c(-c2ccc3c(c2)OCO3)[nH]1 +COCC1CCN(c2nc(N3C4CCC3CC(O)C4)nc3scc(-c4ccccc4)c23)CC1 +CCCc1cc(Cl)c2oc(Cc3ccc(OC)cc3)c(CCC)c2c1O +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(C(F)(F)F)cn1 +COc1ccc(-c2cc(C(N)=O)c3nc4[nH]c(OC)ccc-4c3n2)cc1 +N#Cc1cc(N2CCN(CCC3CCC(NS(=O)(=O)c4cccc(C#N)c4)CC3)CC2)cc(C(F)(F)F)c1 +CCCCN(C)c1ccc(N=Nc2ncc([N+](=O)[O-])s2)c(C)c1 +OCCCNc1cnc(F)c(-c2cncc(Nc3cccc(Cl)c3)n2)c1 +FC(F)(F)c1ccc(CCNCC(c2ccc(C(F)(F)F)cc2)N2CCN(C3CCCCC3)CC2)cc1 +FC(F)(F)c1cccc(-n2cc(-c3ccccc3NCc3ccncc3)nn2)c1 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+O=C(NCc1ccncc1)c1cnc(Oc2ccc3c(c2)CCC(c2cccc(O)c2)O3)s1 +NCCCCN(CC1Cc2ccccc2CN1Cc1ccncc1)C1CCCc2cccnc21 +COc1ccc2c(c1)C(=O)C(c1cccc(Cl)c1)=[N+]2[O-] +Oc1ccc2c(c1)C13CCN(CCc4ccccc4)C(CCC1O2)C3 +N#CC=C(Nc1cccc2c(Cl)c[nH]c12)NC1CCCCN(CC(=O)N2CCCC2)C1=O +O=[N+]([O-])c1cn2c(n1)OCC(OCc1ccc(-c3ccc(OC(F)(F)F)cc3Cl)nc1)C2 +O=C(NCc1ccc(N2CCCCCC2)c(F)c1)Nc1cccc2[nH]ncc12 +CCc1c(C)nc2c(C)cccc2c1Nc1ccc(N2CCCN(C)CC2)cc1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(F)(F)F)no4)c3)c2cc1OC +CCC(=O)C1C(c2ccc3ccccc3c2)CC2CCC1N2C +CSc1nc(N(C)NC(=O)c2ccc(F)cc2)c2ccccc2n1 +CCc1c(C)[nH]c2cc(OCCCN3CCN(c4ccccc4)CC3)c(Cl)cc2c1=O +CC(=O)c1csc(CNC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)n1 +CC1CN(Cc2ccc(N(C)C(=O)c3ccc(-c4ccc(F)cc4)nc3)cc2)CC(C)N1 +NS(=O)(=O)c1ccc(NC(=O)CN(CCN(CC(=O)O)c2ccccc2O)c2ccccc2O)c(I)c1 +OCC1OC(Oc2ccc(CCc3ccc(O)cc3O)c(O)c2)C(O)C(O)C1O +Cc1cn2c(n1)C(N1CCN(CC(C)(C)C(=O)O)CC1)=Cc1ccccc1C2 +NC(=O)c1cccc(Oc2ccc3c(c2)c(=O)ncn3Cc2c(F)cc(F)cc2F)c1C(F)(F)F 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+Cc1cc(-c2nnn(CC3CCC(C(=O)O)CC3)n2)cc(C(=O)NCc2cccc(O)c2)n1 +Cc1ccc(NC(=O)CC(CC(=O)O)c2noc(C3CC(CC(C)C)C3)c2C2CC2)c(Cl)c1 +CCOc1ccc(-c2nc(C)c(C(=O)O)[se]2)cc1[N+](=O)[O-] +O=c1[nH]cnc2c(CN3CC(O)C(O)C3CO)csc12 +CC(C)CC(=O)NC(Cc1ccccc1)C(=O)C(=O)NCCNS(=O)(=O)c1ccc(-c2ccccn2)s1 +COc1cc2c(Nc3ccc4c(c3)OCO4)ncnc2cc1OCCCN1CCOCC1 +C=CC(C)(C)C1(CC=C(C)C)C(=O)Nc2ccccc2C1=O +NC(=O)N(O)CC1CC1c1cccc(Oc2ccccc2)c1 +CN(C)CCN(C)C(=O)c1cc2[nH]c(=O)c3ccccc3n2n1 +CCc1c(C(=O)NCc2ccc(-c3ccccc3)cc2)c2c(n1CCC(O)CC(O)CC(=O)O)CCCCC2 +CC(C)(C)CCC1(C(=O)c2cnc(N)c(Cl)c2)CCNC1 +COc1ccc(N2C(=O)C(Oc3ccccc3)C2c2ccccc2[N+](=O)[O-])cc1 +Cc1cc(C(N)=O)c2c3ncnc(N4CCN(CCc5ccc(F)c(F)c5)CC4)c3n(C)c2n1 +O=C1CCCN1CCN1CCN(C2CC(c3ccc(F)cc3)c3cc(Cl)ccc32)CC1 +O=C1NCN(c2ccccc2)C12CCN(Cc1ccc3c(c1)OCO3)CC2 +O=C(NCC1(CC2CC2)CN(S(=O)(=O)c2c[nH]nn2)C1)c1ccc(Cl)cc1Cl +O=C(NCC(NS(=O)(=O)c1ccccc1)C(=O)O)c1cc2cc(OCc3ccncc3)ccc2[nH]1 +CC1CCN(CC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)C1 +Cc1ccc(C(=O)C=Cc2ccc(C(=O)NCCNc3ccnc4cc(Cl)ccc34)cc2)o1 +C=C(C)C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +CCCCNc1ncc(C(=O)Nc2ccc(CN3CCOCC3)cc2)c(NC2CCC(O)CC2)n1 +Cn1cc(-c2cc3c(-c4cc(N5CC[S+]([O-])CC5)ncn4)n[nH]c3cc2F)cn1 +CN(C)Cc1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1 +Cn1cncc1CN1CC(N(CC(=O)OC(C)(C)C)S(=O)(=O)c2cccnc2)Cc2cc(C#N)ccc21 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)N3CC(C)(O)C3)c2cn1)c1ccccc1 +CCCN1CCC=C(c2c[nH]c3ccc(C(=O)OC)cc23)C1 +O=C(C1CCN(Cc2ccoc2)CC1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +Cc1ccc2c(c1)NC(c1c(F)cccc1Cl)C1=C(CC3(CCCC3)CC1=O)N2 +Cc1cc(NC(=O)C[N+]23CCC(CC2)C(OC(=O)C2(C4=CC=CC4)CCCCCC2)C3)ncn1 +COc1cccc(C)c1C1CC(Cl)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +O=C(COc1ccc2c(c1)C(O)(C(F)(F)F)c1ccccc1-2)N1CCCC1CO +O=C(Nc1nc(-c2ccccc2)cs1)C1CCCN1C(=O)C(NC(=O)N1CCOCC1)c1ccccc1 +NC(Cc1ccccc1)P(=O)(O)C(O)Cc1ccccc1 +CN1CCC(C(=O)OCc2ccc(-c3ccccc3)cc2)(c2ccc(Cl)c(Cl)c2)CC1 +CN1CC=C(c2c[nH]c3ccc(N=C(N)c4ccco4)cc23)CC1 +Oc1ccc(-c2nc(Nc3cccc(Cl)c3)nc3[nH]cnc23)cc1 +CN(C)c1ccccc1NC(=O)c1cccc2c1C(=O)c1ccccc1-2 +CCCOC1OCc2c(cc3n(c2=O)Cc2cc4ccccc4nc2-3)C1(O)CC +COc1ccc(CNC(=O)C(Cc2ccccc2)NC(=N)NC(=O)Cc2ccc(OC)c(OC)c2)cc1OC +OCCCCNc1ncc(-c2ccccn2)c(NC2CCC(O)CC2)n1 +CCCCc1ncn(Cc2ccccc2)c(=O)c1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(NC(NC(=S)Nc1ccc(F)c([N+](=O)[O-])c1)C(Cl)(Cl)Cl)C(c1ccccc1)c1ccccc1 +CN(C)CCc1ccc(Nc2ncc(Cl)c(-c3ccc(C(C)(C)N)cc3)n2)cc1 +CC(=O)OC1CCCN2C1CC(=O)C(n1cnc3ccccc3c1=O)C2(C)C +CN(C)c1cccc2cc(S(=O)(=O)NCCN3C4C5C6CC7C8C6C4C8C3(O)C75)ccc12 +CNC(=O)c1ccc2cc(C(O)(c3c[nH]cn3)C(C)C)ccc2c1C +CCCNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 +CCOC(=O)C1=C(c2ccc(-n3c(C)nc4cnccc43)cc2)NC(C)=C(C(=O)O)C1c1ccccc1Cl +CCN(CC)C(=O)C=C(C)c1ccc(OCc2c(Cl)cccc2Cl)c(OCC(=O)O)c1 +CC1(O)CCC2CC1OOC2(C)C[S+]([O-])c1ccccc1 +CN(CCCN(C)c1cc(-c2ccco2)nc2cc(-c3ccccc3)nn12)C(=O)c1ccoc1 +CC(C)N(CCN(C(=O)Nc1ccc(F)c(Cl)c1)C1CCC2(c3cccc(CN)c3)CC2C1)C(C)C +COc1cccc(-c2nn(C3c4cc(F)cc(F)c4CC3O)c3c2CN(C(C)=O)CC3)c1 +CC(C)C1C=CC(=O)NCCC=CC(NC(=O)C(NC(=O)NC(C(=O)O)C(C)C)C(C)C)C(=O)N1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1)CC2 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1n[nH]cc1Nc1ncnc2sccc12 +COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3C=Cc3ccccc3)CC12C +CCC(C)C(NC(=O)C(CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCC(N)=O +CC(C)=CCCC(C)=CCCC(C)=CCOC(=O)Nc1cc(CNCCS)nc(CNCCS)c1 +COc1ccccc1N1CCN(CCCN2Cc3ccc4ccccc4c3C2=O)CC1 +COc1ccc(CNC(=O)c2cccc(NC(C)=O)c2)c(C(F)(F)F)c1 +CCCCOC(=O)NS(=O)(=O)c1sc(CCCC)cc1-c1ccc(Cn2ccnc2)cc1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(Cc1ccc(Oc3ccc(C)cc3)cc1)CC2 +Cc1cc(C)c(Oc2cc(NCCN3CCNCC3)nc(Nc3ccc(C#N)cc3)c2)c(C)c1 +Cc1cc(-c2nc3c(cnc4ccccc43)[nH]2)on1 +CC(NC(=O)C=Cc1ccccc1F)c1cccc(-c2cnccn2)c1 +c1ccc(-c2nc(NCCN3CCOCC3)c3nc(NCCN4CCOCC4)c(NCCN4CCOCC4)nc3n2)cc1 +COC1(c2cnc(S(=O)(=O)c3ccc(C(C)=NO)cc3)s2)CCOC(C)C1 +Cc1csc(C(=O)C=Cc2cc3cc(C)ccc3nc2Cl)c1 +CCOc1ccc(Cc2cc3c(cc2Cl)OCCCCCCOCC2OC3C(O)C(O)C2O)cc1 +CC(C)(O)c1cncc(-n2ncc3c(F)ccc(F)c32)c1 +Cn1c(=O)c(-c2ccccc2Cl)cc2cnc(NC3CCOCC3)nc21 +[N-]=[N+]=NCCCCn1c2ccccc2c2ccc3c(C=O)c[nH]c3c21 +O=C(N=C1SSC2=NCCN21)c1cccc2ccccc12 +COc1c(NC(=O)c2ccc(-c3ccc(F)cc3)cc2)ccc2cc(CN3CCCC3)cnc12 +O=S(=O)(c1ccc2c(c1)CCOC2)c1cc(Cl)c2oc3c(c2c1)CNCC3 +CC(C)(C)NC(=O)c1ccccc1CC(O)C(CSc1ccc2ccccc2c1)NC(=O)c1cccc(N)c1Br +O=C(O)CC(NC(=O)C1Cc2ccccc2CN1)C(=O)O +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(OC(=O)NCC(C)(C)C)C(=O)CO +O=C(OCCN1CCC(c2ccccc2)CC1)C1(c2ccc(Cl)cc2)CCCC1 +O=C(Nc1ncc(C(=O)NCCc2ccccc2)c2nc(-c3ccco3)nn12)NC1CCCCC1 +CC1CN(C)CCC1c1cc2c(cc1-c1ccccc1F)OCC1=NNC(=O)C(C)N12 +COc1ccc(C(=O)C(Cc2ccc3c(c2)OCO3)=C(C(=O)O)c2ccc3nsnc3c2)cc1 +CC1CCC(Cn2c(N3CCOC(C)(C)C3C)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CC1CCCN1CCc1ccc(-c2ccc(S(=O)(=O)NCC3CC3)cc2)cc1 +CCCOc1cc(OCCCN2CCCC2)ccc1C(=O)Nc1cccc(O)c1 +O=C(Nc1cnccc1OCC1CCOCC1)c1csc(-c2c(F)cccc2F)n1 +CCOc1ccc(C(=O)Nc2ccc(C3CNCCO3)c(F)c2)cn1 +O=C(C=Cc1ccn2c(CN3CCCC3)c(-c3ccccc3)nc2c1)NO +COc1ccc(CCNCC(O)COc2ccc(-c3nc(C(N)=O)c[nH]3)cc2)cc1OC +Nc1noc2ccc(-c3ccccc3Oc3cc(F)c(S(=O)(=O)Nc4ncns4)cc3F)cc12 +CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccncc21 +COc1cccc(CNCCCNc2ccnc3cc(Cc4cc(C)cc(C)c4)ccc23)c1O +CC(C)c1sc(Cl)nc1C(=O)NCCc1nc(C(=O)Nc2ccc3c(c2)OCO3)cs1 +COc1cccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)c1 +CC(OC1CN2C(=O)CC(O)C2C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)CC5CCOCC5)C4)c3C2)cc1C#N +COc1c(NCCCc2ccccc2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(O)(CC#N)C2 +COC(=N)NS(=O)(=O)c1ccc(NC(C)=O)cc1 +O=C(Nc1ncnc2[nH]cnc12)c1cccc(-c2ccccc2)c1 +COC(=O)c1cccc2[nH]c3c(C(N)=O)cc(-c4cccc(OC)c4)cc3c12 +CC=CC(=O)Oc1ccc2sc(S(N)(=O)=O)nc2c1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1csc2ccccc12 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)cc1C(=O)NCC(CC(C)C)C(N)=O +COC(=O)c1csc(CN2CC(C)(C)C(Oc3ccc(C#N)c(C(F)(F)F)c3)C2=O)n1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)n[nH]2)cc1Nc1ncnc2c(N)nc(N3CC4CC3CN4)nc12 +Cc1cc(C)c(C=C2C(=O)Nc3ccc(-c4ccc5cn[nH]c(=O)c5c4)cc32)[nH]1 +Cc1ccc(C(=O)N2CC(F)(c3ccc(C#N)cc3)C2)cc1-c1[nH]nc(C)c1C +CCCSc1nc(SC(CC)C(N)=O)nc2c1ncn2-c1ccccc1 +COc1c(C=Cc2ccc(NS(C)(=O)=O)cc2)cc(-c2c[nH]c(=O)[nH]c2=O)cc1C(C)(C)C +N=C(N)c1csc(CNC(=O)C2CCCN2C(=O)C(NS(N)(=O)=O)C(c2ccccc2)c2ccccc2)n1 +CCS(=O)(=O)CCOC12COc3c(F)ccc(F)c3C1(S(=O)(=O)c1ccc(Cl)cc1)CCC(=O)C2 +CCc1[nH]c2nc(Oc3cnc4cccnc4c3)nc(N3CC4C(N)C4C3)c2c1Cl +COc1cccc(C(=O)NC(CCC2CCCCC2)C(=O)NC(CN2CCc3cc(F)ccc32)C(C)O)c1 +CC(NC(=O)c1cnn(C)c1)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 +CC(C)(C)c1ncc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1 +CCOC(=O)CCCn1c(=O)oc2cc3ncnc(Nc4ccc(C(=O)OCc5ccc(Cl)cc5)cc4)c3cc21 +COc1ccc(-c2cccc3c(=O)n(-c4ccc(N5CC(C)OC(C)C5)nc4)cnc23)cc1 +CC1CCCN1CCc1cc2cc(-c3cccc(C(C)(C)O)c3)ccc2o1 +CSc1ncc(C2C(C(=O)OCc3ccccc3)=C(C)NC(C)=C2C(=O)OC(C)C)n1Nc1ccccc1 +CC(C)n1nnnc1-c1cccc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3)C2)c1 +O=C(CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1)NO +COc1cc(F)c2[nH]c(-c3c(C)nn(C)c3C)c(C=C3Oc4ccc(NC(=O)Nc5cccnc5)cc4C3=O)c2c1 +CC(C)(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)C(N)C(=O)N1CCCC1C#N +CCCNC(=O)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +O=C(Nc1cccnn1)N1CCN(c2ccnc(-c3ccc(F)cc3F)n2)CC1 +CCN(CC)CC(=O)N1CCc2nc(Nc3ncc4c5ccncc5n(C5CCC(C)CC5)c4n3)ccc2C1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CN(CC(=O)O)Cc2cccc3ccccc23)cc1 +COc1ccccc1N1CCN(Cc2ccc(-c3ccc(F)cc3)[nH]2)CC1 +CCC(C1CC1)n1nc(C)nc(Nc2ccc(OC)nc2C(F)(F)F)c1=O +Cc1c(-c2ccc(C(C)(C)C)cc2)nc2ccc(F)cc2c1C(=O)O +Cc1c(C(=O)OC(C)C(C)(C)C)c[nH]c1C(=O)Oc1c(F)c(F)c(F)c(F)c1F +O=C(O)C1(Cc2cccc(Nc3nccs3)n2)CCC(Sc2cccc(Cl)c2Cl)CC1 +O=C(O)c1csc(-n2nc(C3=CCCCC3)c3ccccc32)n1 +CCOC(=O)c1ccc(-c2nn(Cc3ccccc3F)c3ccccc23)cc1 +Cc1cccc(NC(=O)N(C)Cc2ccc(-c3n[nH]c4c3Cc3cc(CN5CCN(C)CC5)ccc3-4)s2)c1 +O=C(Cc1ccccc1)NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1 +COCc1c(CN2CCNC(=O)C2)c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn12 +CCOc1cccc(F)c1C1CC(C)C(=O)N1Cc1cnc2ccccc2c1 +Cc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)CCC3)cc1 +CC1CCC2(O)C3(C)CC4(O)OC2(C1O)C1(O)C3(O)C(OC(=O)c2cc[nH]c2)C(O)(C(C)C)C41C +CC(C)c1cc(C(C)C)nc(N2CCN(c3ccnc(C(C)O)n3)CC2)n1 +CS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(c2ccccn2)CC1 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+O=C(Nc1cc(Oc2cncnc2)ccn1)c1cccc(Cl)c1 +N#CC(=C1Nc2ccccc2S1)c1ccnc(NCCc2ccc(N)cc2)n1 +Cc1c(C2CCN(Cc3ccccc3)CC2)n[nH]c1-c1ccccc1 +NC(CCc1ccccc1Oc1ccccc1)(C(=O)O)C1CC1C(=O)O +COc1ccc(-c2c(C(=O)O)c(=O)n(Cc3ccccc3OC)c3c2oc2cc(N)ccc23)cc1 +COc1ccc(C(=N)NC(C)C)cc1-c1cc2ccc(C(=N)NC(C)C)cc2o1 +Cn1cc(S(=O)(=O)Nc2ccc(-c3ccc4c(N)n[nH]c4c3)cc2)c(C(F)(F)F)n1 +CN(C)c1ccc(-c2nc3c(s2)C(O)CCC3)c(CO)c1 +CCN1Cc2cccc(Oc3nc(Nc4ccc(C(=O)NC5CCN(C)CC5)cc4OC)ncc3C(F)(F)F)c2C1=O +NC1CCC(Nc2cc(-c3nc(NCC4CCOCC4)c(Cl)cc3Cl)c(Cl)cn2)CC1 +O=C(NCC(c1ccccc1)c1ccc(C(F)(F)F)nc1)c1ccc(Cl)cc1Cl +O=C(O)CC1CCN(C(=O)OC2(C3COCC(C4CC4)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1 +CSc1ccc(Cc2cccc(-c3c(O)nc4cc(Cl)ccc4c3O)c2)cc1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C(C)O)nc1C +C#Cc1cccc(Nc2nc3cc(C(=O)O)ccc3c3cnccc23)c1 +CNCc1cc(OCc2ccc3c(C)cc(N)nc3c2)cc(C#N)c1F +COCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NCc2ccc3ncccc3c2)C(C)C)nn1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CN(C)C)c4ccccc4)ncc23)ccn1 +O=C(O)Cc1c2n(c3cc(Cl)ccc13)CC(N(CC1CC1)c1ncc(F)cn1)CC2 +O=C(O)C(Sc1nc(Cl)cc(Nc2nc(-c3ccc(Cl)cc3)cs2)n1)c1cccc2ccccc12 +CCCc1n[nH]c2c1C(c1ccc(SC)cc1)c1c(nc3c(c1N)CCCC3)O2 +CC(C)C(CO)N=C(N)c1c(O)nsc1Nc1ccc(Oc2cc(Cl)ccc2Cl)cc1 +Cn1c(=O)c(C=Cc2ccc3c(c2)OCO3)nc2ccccc21 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1ccc(C(F)(F)F)cc1 +CCCC(=O)c1cnn(-c2ccc(OC(=O)c3cn(CC(=O)N4CCN(C)CC4)c4ccc(Cl)cc34)cc2)c1C +CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1cc(N)cc(C(=O)O)c1 +CC(NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(C5CC5)ccc34)nc12)C(=O)N1CC(C#N)C1 +O=C1N(c2cccc(Cl)c2)CCN1C1CN2CCC1CC2 +CC(C)N1CCC(NC(=O)c2ccc(OC3CCN(C4CCC4)CC3)cc2)CC1 +CC(C)(C)NC(=O)N1CCC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CC1(C)OB(c2ccccc2NC(=O)c2ccc(Oc3ccc(C(F)(F)F)cc3)nc2)OC1(C)C +COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4c(C)nn(C)c4C)nc3c2)c1 +O=C(c1nn(C2CCCN(CCN3CCOCC3)C2)c2c1CS(=O)(=O)c1cc(F)ccc1-2)N1CCOCC1 +CCC(NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)c1ccccc1 +O=C(O)COc1ccc(OC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 +O=S(=O)(NC(CCCN1CCN(c2ncc(F)cn2)CC1)C1CCCCC1)c1ccc(F)cc1 +COc1ccc2c(c1)COC(=O)N2C1CCN(CC(=O)Nc2ccc3c(c2)-c2ccccc2C3=O)CC1 +CC(C)CCN1CC(C)N(C(=O)CCc2cccnc2)C(C)c2c(F)cccc21 +NC1=NC(CF)(c2cc(NC(=O)c3cc4ccccc4cn3)ccc2F)C2CC2O1 +CCc1nc2c(n1Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)CCCC2 +CCOCn1c(Cc2ccccc2)c(C(C)C)c(=O)[nH]c1=O +COc1ccc(C2=NN(C3CCCCCC3)C(=O)C2(C)C)cc1OCc1ccccc1 +CNc1nc(Nc2cc(OC)c(-c3nccn3C)cc2Cl)ncc1C(F)(F)F +COc1cc(C(=O)N2CCC2c2noc(-c3ccccc3OC(F)(F)F)n2)c(-n2nccn2)cc1Cl +O=C(C1CCN(c2cc(Oc3ccc(F)cc3)ncn2)CC1)N1CCc2ccccc2C1 +COc1cccc(NC(=O)Nc2ccccc2C(O)CN2CCC(Cc3ccccc3)CC2)c1 +CCN(C)c1nc2ccc(C(=O)N(CCN3CCOCC3)CC(O)C(Cc3ccccc3)NC(=O)OCc3cncs3)cc2o1 +O=C(O)CSC(=O)C(CCCCNC(=O)Cc1cccs1)NC(=O)Cc1cccs1 +N#CC1CC1C(=O)N1CCN(c2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(F)c5)CC4)cc3)cc21 +CCN(CC)CCCC(CC(C)C)NC(=O)CCOc1cc(-c2cc(Cl)cc(Cl)c2)nn1-c1ccc2ccccc2c1 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+O=c1ccc(-n2ccnc2)nn1CCN1CCN(c2ccccc2Cl)CC1 +CS(=O)(=O)N1CCCC2C3c4cc5c(cc4CCN3CCC21)OCO5 +Cc1c(P(=S)(c2ccccc2)c2ccccc2)n2ccccc2[n+]1CC=Cc1ccccc1 +CCOC(=O)Nc1noc2cc(-c3c(-c4ccccn4)n[nH]c3C)ccc12 +CONC(=O)c1cnn2ccc(N3CCCC3c3cccc(F)c3)nc12 +Cc1c(F)cccc1Oc1c(C(=O)N2CCNCC2)c2ccccc2n1-c1ccccc1 +N#Cc1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)cc1 +Nc1ccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2cc3ccccc3s2)cc1 +CC(C)(O)Cn1cc(-c2nc(C(C)(c3ccc(-c4cnc(N)nc4)nc3)C3CC3)no2)cn1 +CCCCCCC(NC(=O)c1ccc(C#N)cc1)C(C)(C)C(=O)NC(Cc1ccccc1)C(=O)OCC +Cc1c(C2CC2)nc2ccc(NC(=O)c3ccc(-c4ccc(F)cn4)cc3)cn12 +COCc1cc(COc2ccc(C3(N)CCN(C(C)C(=O)NO)C3=O)cc2)c2ccccc2n1 +[H]C([H])(F)Oc1cccc(NC(=O)c2ccccn2)c1 +CC1OC(=O)C1NC(=O)OCc1ccc(C(C)(C)C)cc1 +CCCC(=O)NCCc1c(-c2ccccc2)[nH]c2ccccc12 +Cn1c(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)nnc1-c1cccnc1C(F)(F)F +COc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C +FC(F)(F)c1ccc(-c2ccoc2C2=CN3CCC2CC3)cc1 +CCCN(CCC)C1COc2c(cccc2-c2ccc(OC)cc2)C1 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+N#Cc1ccc(Cn2cncc2CNC2CCN(Cc3cccc(Cl)c3)C2=O)cc1 +COCCCNc1ncnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)(F)C2)CCN1Cc1ccc(Cl)c(F)c1 +CCc1ccc(NC(c2ccc(Cl)c(C)c2)C(F)(F)F)cc1CN1CCC(C(=O)O)C1 +Cc1ccc(-c2sc(C)nc2C(=O)N2CCC2c2nc(-c3cccc(Cl)c3C)no2)cc1 +CCN(CC)C(=O)c1ccc(C(c2cccc(OC)c2)N2CC(C)NCC2C)cc1 +COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CCC(O)C2)c(OC)n1 +COc1ccc(Cn2c(N=CN(C)C)nc3c2c(=O)n(CC2CC2)c(=O)n3CC2CC2)cc1 +CC(=O)OCC1OC(NC(=O)CCCn2[se]c3ccccc3c2=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +COc1ccc(C#Cc2c(N)ncnc2NC(C)c2nc3c(F)cccc3c(=O)n2-c2ccccc2)nc1 +O=C(NCc1cccc(OC(F)(F)F)c1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +N#CC1CNCC1NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +N#Cc1nccc(N2CC(S(=O)(=O)c3ccccc3C(F)(F)F)CC2C(=O)O)n1 +CN(C)c1ccc2ncc(F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CCCC(=O)NO +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2Cc3ccncc3C2)c(-c2cncnc2)c1 +COc1cc(N2CCN(Cc3ccccn3)CC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)C4CC4)ncc3Cl)C2)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(OC4CCC4)nc3)C2)cc1 +COc1cc(C=C2SC(=O)NC2=O)ccc1Oc1ccc(C#N)c(C#N)c1 +O=C(O)CC(NC(=O)CNC(=O)c1cccc(NC2=NCC(O)CN2)c1)c1cc(Br)cc(Br)c1O +COc1ccc(Oc2c(Cl)cnn(Cc3cccc4ccccc34)c2=O)cc1 +COc1cc(-n2ccnc2)ccc1Nc1cc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +CC(Nc1ncnc(N)c1-c1cc(O)cc(F)c1)c1nn2cccc2c(=O)n1-c1ccccc1 +Cc1c(Br)c(C)c2c(c1Br)OC(C(F)(F)F)C(C(=O)O)=C2 +CC(C)(C)NC(=O)C1CN(CCc2ccccc2)CCN1CC(O)C(Cc1ccccc1)NC(=O)OC1CCOC1 +O=C(c1ccsc1)c1cnn2c1n[n+]([O-])c1ccc(Cl)cc12 +COc1cc(N2CCN(C)CC2)ccc1Nc1nc(N)n(C(=O)NCc2c(Cl)cccc2Cl)n1 +CCCCS(=O)(=O)NC1CCC(Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +CC(O)C(N)C(=O)NC(Cc1cn(C=O)c2ccccc12)C(=O)NC(Cc1ccccc1)C(=O)N(C)Cc1ccccc1 +CCOC(=O)c1ncn2c1Cn1cnnc1-c1cc(OC)ccc1-2 +N=C(N)c1cccc(Oc2ccc(NC(=O)NCC(N)=O)c(Oc3cccc(C(=N)N)c3)n2)c1 +Cc1ccc(NS(=O)(=O)c2ccc(C=CC(=O)NO)cc2)cc1 +C(=Cc1ncc2ccccc2n1)c1cn2c(-c3ccc(N4CCNCC4)nc3)cnc(N3CCOCC3)c2n1 +N=C1SC(=Cc2ccc(-c3cccc(Cl)c3)o2)C(=O)N1c1nccs1 +O=C(NCCCCN1CCN(c2ccc3ccccc3n2)CC1)c1cn2ccccc2n1 +O=C1N(Cc2ccc(CO)cc2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc(CO)cc1 +CCCCOCc1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1ncnc(C)c1C(=O)N1CC2CN(CCC(c3ccccc3)C3CCN(CC(F)F)CC3)CC2C1 +Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(C)c3ccccn3)cc12 +CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)NCc1cccc(F)c1)c1ccccc1)C(C)C +CC(=O)N1CCN(Cc2ccc(-c3cccc4nc(NC(=O)C5CC5)nn34)cc2)CC1 +CN(CCCNC(=O)c1cccc2cccnc12)CCCNc1n[n+]([O-])c2ccccc2[n+]1[O-] +O=C1CCN(c2ccccc2C(=O)NCc2ccc(-n3cccn3)cc2)C(=O)N1 +CN1CCN(C(=O)c2cnccn2)C(C)(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)[nH]2)C1 +Cc1cc(-c2ccccc2S(N)(=O)=O)ccc1C(=O)NC(CCCN=C(N)N)B1OC2CC3CC(C3(C)C)C2(C)O1 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(-c3ncc(F)s3)cc2)c2ccc(OCc3ccccn3)cc12 +COc1ccccc1N1CCN(CCCN2CCCCn3c2nc2c3c(=O)n(C)c(=O)n2C)CC1 +O=C(Nc1cc(-c2ccccc2)nn1-c1ccccc1Cl)c1ccccc1 +O=C(Nc1ccccn1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +COc1cccc(OC)c1-c1cc(C(=O)NC2C3CC4CC(C3)CC2C4)nn1-c1ccnc2cc(Cl)ccc12 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(-c3cccc(OC(F)(F)F)c3)cc2)cc1 +CCNc1c2c(nc(N)n3nc(-c4ccco4)nc23)nn1C +O=C(NC1CCCCC1)c1cccn(Cc2ccccc2)c1=O +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NC1COC1 +Cc1ccc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NC(C)c2ccccc2)cc1 +COc1ccc(C2CN(c3nc(-c4ccncn4)cc(=O)n3C)CCO2)cc1 +O=C(NCC1(c2cnc(C(F)(F)F)nc2)CCC(F)(F)CC1)c1cccc(Cl)c1Cl +CCn1c(Nc2ccc(F)cc2Cl)nc2cnc(Oc3c(F)cccc3F)nc21 +CN1CCN(CCCN(Cc2nccc3c4ccccc4n(CC(=O)N4CCOCC4)c23)C2CCCc3cccnc32)CC1 +CC1CN(Cc2ccc(N(C)C(=O)c3ccc(-c4cccc(F)c4)nc3)cc2)CCN1 +CC(C)(C)c1csc(NC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)n1 +Cc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2CC(=O)O)cc1C +Nc1nnc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)s1 +Cc1cc(NC(=O)c2cnn3ccc(N)nc23)n(-c2cc(Cl)ccc2C)n1 +CN1CCN(c2ccc(C=C(C#N)c3ccccc3Br)cc2)CC1 +CN1CCCC(NC(=O)c2c(C(N)=O)nc3n2CCOc2cc(F)c(C#CC(C)(C)O)cc2-3)C1 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+C=C1C(=O)OC2CC3(C)OC3CCC3(C)OC3CC12 +COc1ccc(COc2nc(N3CC4CC4C3)ncc2C(=O)NCCN2CCOCC2)cc1Cl +Cc1c(C(=O)NS(C)(=O)=O)sc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c12 +Cc1[nH]c2c(c1C(=O)NCCN1CCOCC1)CCCC2=C1C(=O)Nc2ccc(F)cc21 +COCCNC1=NC(=Cc2ccc3c(c2)OCO3)C(=O)N1C +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2cnn(C)c2)cn1C(C)C +CCN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +O=S(=O)(c1ccc(O)nn1)c1oc2ccc(Cl)cc2c1-c1ccccc1 +COC(=O)N1CCN(Cc2cnc(Nc3ccc(OC)nc3)c(-c3nc(C)nc(N)n3)c2)CC1 +CONC(=O)c1cc(Nc2ncnn3cc(NC(=O)OC4CCN(C)CC4)c(C(C)C)c23)c(F)cc1F +CCCCC(N)C(Cc1ccsc1)NC(=O)c1cc(NCC2CC2C)nc(N(C)S(C)(=O)=O)c1 +CN1CCN(c2ccc3c(c2)sc2nc(-c4ccc(NC(=O)Nc5cc(C(C)(C)C)on5)cc4)cn23)CC1 +Cc1c(-c2nnc(-c3ccco3)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCCn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 +Cc1nc2ccccc2nc1CCc1nc(C(=O)NCC2CCCO2)cc(N2CCCC2)n1 +Oc1cccc(-c2cc(-c3cccs3)nc3c2COc2ccccc2-3)c1 +COc1cccc(C(=O)Nc2ccc3c(c2)C(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)C(O)CC3)c1 +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)cc1 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+O=C1N(Cc2ccncc2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc2ccccc2c1 +CN(C)CCNC(=O)c1cccc2c(N)c3cccc(C(F)(F)F)c3nc12 +Cc1n[nH]c2nc3ccc(C(F)(F)F)cc3c(CN3CCCOCC3)c12 +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)c(F)c2)c1 +COC(=O)C(C)NP(=O)(OCC1C=CC(n2cc(C)c(=O)[nH]c2=O)O1)Oc1ccc(C#N)cc1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3cccc(Cc4ccccc4)n3)C12 +COc1n[nH]c2cc(NC(=O)NC3CCCN(C(=O)OCc4ccccc4)C3)ncc12 +CCCCn1c(=O)c(C(=O)NC2CC3CCC(C2)N3C)c(O)c2cccnc21 +COC(=O)C1C(C=NCCO)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +CC1(O)C(O)C(CCl)OC1n1cnc2c(NC3CCCC3)nc(Cl)nc21 +O=c1[nH]c2c(O)ccc(C(O)CNCCc3ccc(CNCCc4ccccc4)cc3)c2s1 +CC(Nc1ncnc2[nH]c(-c3ccc(NC(=O)CCCCCCC(=O)NO)cc3)cc12)c1ccccc1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(nnc2-c2ccncc2)C1 +O=C(c1ccc(C(F)(F)F)cc1)N1CCN(C(c2ccc(Cl)cc2)c2cncnc2)CC1 +CC1(O)CC(c2nc(-c3ccc(C(=O)c4ccccc4)cc3F)c3c(N)nccn23)C1 +COc1ccc(C(=O)C(Cc2ccc(OC)c(OC)c2OC)=C(C(=O)O)c2cc(OC)c3c(c2)OCO3)cc1C +O=C1CC(NC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(Cl)cc3Cl)n(-c3ccccc3)n2)CN1 +CC(=O)NC(C)Cc1ccc(C#Cc2ccc(OCC(C)C)cc2)cc1 +Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(C(=O)NC(C)(C)C)cc1 +COc1ccc(C2=NN(C)C(=O)C3CCCCC23)cc1OC +N=C(N)Nc1ccc(S(=O)(=O)c2ccc(NC(=N)N)cc2)cc1 +COc1ccc(-c2cc(-c3ccc(S(C)(=O)=O)c(F)c3)cnc2N)cn1 +COc1ccccc1C=NNc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Cc1c2c(n3c1CCCN(C(=O)CN)C(C)C(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +CCCCCCCCOc1ccc(-c2cc(C(=O)O)c3cnn(Cc4ccncc4)c3n2)cc1 +Cc1cncc(-c2cnc(NC3CCNCC3OCC3CCCCC3)c3[nH]c(=O)c(C)cc23)c1 +O=C(Nc1cnn(-c2ccccc2)c1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +NC(=O)C(Cc1ccccc1)NC(=O)C(CS)NC(=O)C(F)(F)F +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(C(F)(F)F)ccc2Oc2ccnc(N3CCOCC3)n2)cc1 +COc1cc(OC)cc(C(C)N(C(=O)C2CNCCO2)C2CC2)c1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cccc(C5CCNCC5)c4)nc23)cc1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2ccncc12 +CCNc1nccc(-c2nc(C3CC3)[nH]c2-c2cc(F)cc(NS(C)(=O)=O)c2Cl)n1 +CSc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1ccc2c(c1)OCO2 +N=C(N)c1ccc(-c2cc(-c3ccc(C(=N)N)cn3)on2)cc1 +CC(C)n1cnc2c(-c3ccc(F)c(-c4ccc(S(=O)(=O)C(C)C)cc4F)c3)cnnc21 +CC(OCC(O)CNC(C)(C)Cc1ccc2ccccc2c1)c1cccc(-c2ccc(C(=O)O)cc2)c1 +[C-]#[N+]c1cccc(-c2cc(C(=O)Nc3ccc(C4CNCCO4)cc3)n[nH]2)c1 +Cn1cncc1C(OCc1ccc(C#N)nc1-c1cccc(Cl)c1)c1ccc(C#N)cc1 +c1cc(-c2n[nH]c3ccc(-c4nnn[nH]4)cc23)cs1 +Cc1ccc(Oc2ccc(N(CC(O)C(=O)NO)S(=O)(=O)Cc3ccccc3)cc2)cc1 +CCCCCn1cc(C(=O)NC2C3(C)CCC(C3)C2(C)C)c(=O)c2ccc(Sc3ccccc3)cc21 +Cc1cc(NC(=O)CC(=O)O)c2c(c1Oc1ccc(O)c(CCc3ccc(F)cc3F)c1)CCC2 +O=C(NC(c1ccccc1)c1ccccc1)c1ccc2nc(NC3CCC(O)CC3)c3nccn3c2c1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc[n+]([O-])c2)c1F +CC(=O)Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 +Cc1nnc(C(C)C)n1C1CC2CCC(C1)N2CCCN(C(=O)NCc1ccccc1)c1ccccc1 +O=C1NCC(C(=O)Nc2cc(-c3cccc(COCCC(F)(F)F)c3)n(-c3ccccc3)n2)N1 +COc1ccc2c(c1)-c1[nH]nc(NCc3c(C)cccc3Cl)c1C2 +CC(C)(C(=O)Nc1nncs1)C1c2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)nc2Oc2c(F)cccc21 +NC(=O)c1cc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)no1 +NC(=O)c1cccc2c(NCc3ccc(F)cc3F)ncnc12 +Cc1cc(N2CCNCC2)c2c(c1)N(S(=O)(=O)c1ccccc1C#N)CCO2 +O=C(OC1C[N+]2(CCc3ccccc3)CCC1CC2)C1c2ccccc2Oc2ccccc21 +O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(Oc3ccccc3)ccc21 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2nc(CCc3ccccc3)cs2)cc1 +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)Nc1cnc2ccccc2c1 +CNc1nccc(-c2ccc3c(c2)CCC(C)N3C(=O)c2ccc(O)cc2O)n1 +Cc1ncc(NC(=O)c2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2Cl)s1 +CCCCCCCCCCCC(=O)NC(CNC(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1 +Cc1nc2c3ccccc3nc(SCc3nc(-c4ccccc4)cn3C)n2n1 +Cc1ccc(CN2CCCC2)cc1NC(=O)c1ccc(Nc2ncc(C)c(-c3ccc(OC(F)(F)F)cc3)n2)cc1 +Cc1cc(N2CC3CCN(C(=O)c4cc(F)ccc4-n4nccn4)CC32)ncn1 +O=C(NC1c2ccccc2CC1O)C(Sc1ccccc1F)C(O)C(O)C(Sc1ccccc1F)C(=O)NC1c2ccccc2CC1O +COCCCCN1CCC23Cc4nc5ccccc5cc4CC2(O)C1Cc1ccc(O)cc13 +Cc1cc(C)cc(Sc2c(C)c(=O)[nH]c(=S)n2COCCO)c1 +Cc1nc(N2CCC(N3CCCC3=O)CC2)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +CNC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4cccc(Cl)c4)c(F)cc3F)cc1CC2 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCN(CC(=O)O)CC3)cc12 +Cc1csc(C(=O)NC23CCCC(C#Cc4cnccn4)(CC2)C3)n1 +Cc1cccc(-n2cc3c(n2)c(NC2CCCC2)nc2ccccc23)c1 +O=C1NS(=O)(=O)c2cc(-c3cnc(N4CCOCC4)c4nc(CCc5ccc6ccccc6n5)cn34)ccc21 +Cc1noc(C)c1S(=O)(=O)NC(CCC(=O)N1CCC2(CC1)CCN(c1ccc(C(=N)N)cc1)C2=O)C(=O)O +O=C(Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1)c1ccco1 +Cc1cc2c3c(c1)n(CC(=O)Nc1ccc4c(c1)CC1(C4)C(=O)NC(=O)N1C)c(=O)n3CC(=O)N2 +Cc1ccc(CCc2cccc(C3OC(CO)C(O)C(O)C3O)c2)cc1 +CN(C)CCNc1ccc2c(=O)n(CCN(C)C)c3c4cc5c(cc4ncc3c2c1)OCO5 +CCc1ccc(Cc2nn(C3OC(CO)C(O)C(O)C3O)c3ccccc23)cc1 +NC(CC(CC=Cc1ccc2ccccc2c1)C(=O)O)C(=O)O +N=C(N)Nc1ccc(Cc2ccc(N3C(=O)N(Cc4ccccc4)N=C(C4CCCCC4)c4ccccc43)cc2)cc1 +COC(=O)C1(C)C(O)CCC2(C)c3cc4c(cc3C(O)CC21)[nH]c1ccccc14 +O=C(CCCN1CCc2c([nH]c3ccccc23)C1)c1ccccc1 +CC(O)c1ccc(N2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)nc1 +Clc1cccc(N2CCN(CCCCCCN3CCN(c4cccc(Cl)c4)CC3)CC2)c1 +Oc1ccc(CC2CCN(CCCCc3ccccc3)CC2)cc1 +CC(=O)N1CCc2cc(Br)cc(S(=O)(=O)N(CC(C)C)CC(C)C)c21 +O=C(Nc1ccc([N+](=O)[O-])cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1 +COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O +Cc1nc(-c2cccc(C=CC(=O)NO)c2)n(CCN2CCOCC2)c1-c1ccccc1 +CCOc1ccc2cc(-c3nn(CC(C(C)C)N(C)C)c4ncnc(N)c34)ccc2c1 +Cc1cccc(-n2cc(-c3ccc(S(N)(=O)=O)s3)nn2)c1 +NC1(c2ccc(-c3nc4ccc(-c5ncc[nH]5)cn4c3-c3ccccc3)cc2)CCC1 +CC(C)(C)c1ccccc1N1CCN(C(=O)c2ccc(OCC3CCNCC3)cc2)CC1 +Cc1ccc(NC(=O)c2ccc(N(CCCl)CCCl)cc2)cc1Nc1nccc(-c2cccnc2)n1 +CN1C(=N)NC(C)(c2sc3c(-c4cnn(-c5ccccc5)c4)cccc3c2F)CS1(=O)=O +CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2ccccc21 +COc1ccc2c(Oc3ccc(NC(=O)c4c(CN5CCCC5)n(C)n(-c5ccccc5)c4=O)cc3F)ccnc2c1 +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(Cl)nc4)cc3)nc(N(C)C)nc2c1 +C#CCN(Cc1ccc(OC)cc1)c1cc(OCC2CC2c2ccc(OC)cn2)nn(C)c1=O +CC(C)C(C(=O)NC(CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 +CCOC(=O)C(C)NP(=O)(OCC1OC(n2cc(F)c(=O)[nH]c2=O)CC1O)Oc1ccccc1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(=O)n(C)ccc2n1CC(=O)O +CCC1=CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 +COc1cccc2c1nc(Nc1c(C)cccc1Cl)c1cncn12 +CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(C(Oc2cccc(Cl)n2)c2ccc(OC(F)(F)F)cc2)CC1 +COC(=O)COc1ccc2c(NC(=O)N3C(C(=O)NCc4cccc(Cl)c4F)CC4CC43)cn(C(N)=O)c2c1 +Cc1ccccc1C(=O)Nc1ccc2nc(-c3ccc(N(C)C)cc3)oc2c1 +c1cc(C2=NCCN2)ccc1CC1CCCN(c2ccc(C3=NCCN3)cc2)C1 +CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)C3CCC(NCc4cccc(C(F)(F)F)c4)CC3)sc12 +CC(NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OCC2CC2)c1 +CC(C)(C)NC(=O)C1CCC2C3CCC4=C(O)C(=O)CCC4(C)C3CCC12C +NC(=O)c1ccc(F)cc1OCc1ccc(F)c(C(=O)N2CCNCC2)c1 +CC(=O)C1CCC2(C)C3CCC4C(C)(C)C(=O)CCC45CC35CCC12C +Cn1c(=O)c2c(nc(Br)n2CCSc2nc3ccccc3o2)n(C)c1=O +Cc1cccc(C)c1CNc1nccc2c(C)c(C)[nH]c12 +Cc1cccc(C(CC(C)C)NC(=O)c2cc(COc3cccc(C#N)c3)ccc2CCC(=O)O)c1 +O=C(c1ccc(-c2ccccc2)cc1)c1cc(C(=O)C(F)(F)F)n(-c2cnn(O)c2)c1 +Cn1ccc2ccc3c4[nH]c5c(CCCNCCO)cccc5c4c4c(c3c21)C(=O)NC4=O +COC(=O)CCC(=O)Nc1nc2c(s1)CC(NC(=O)c1cc(Cl)c(Cl)[nH]1)CC2 +O=C(C=Cc1ccc(OC(F)(F)F)c(F)c1)NCC1CCN(Cc2cc(Cl)cc(Cl)c2)C(=O)C(CCN2CCCCC2)N1 +Cc1ccc(O)c(Cn2c(NC3CCN(CC(O)C(C)(C)C)CC3)nc3c(C)cccc32)n1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(Cn5cc6ccccc6n5)C4)cc23)ccn1 +CN(C)CC(C)(C)Oc1ccc(-n2ccc(OCc3ccccc3)cc2=O)cc1 +CNCC1CCC(C(=O)N2CC(c3ccc(C)cc3)C(c3ccc(C#N)cc3)C2)CC1 +CCNc1nc2cc(C#CCCO)c(Cl)cc2nc1NCCCN1CCN(C)CC1 +Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccc(Cl)cc2)s1 +Cc1cccc(CNC(N)=NC(=O)c2ccc(CC(N)C(=O)O)cc2)c1N1CCCCC1 +Cc1ccc(Nc2nc(NCc3ccccc3)c3ccccc3n2)cc1 +CN(C(=Nc1ccc(C(=O)NCCc2ccc(Cl)cc2Cl)cc1)NC1CCCCC1)C1CCCCC1 +O=C(CCC1=CCCN(CCc2ccc(C(F)(F)F)cc2)C1=O)NO +CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc([N+](=O)[O-])cc3)ccc21 +CCC(NC(=O)CCc1ccc(-c2cccc([N+](=O)[O-])c2)cc1)C(=O)NC(CCC(=O)O)C(N)=O +Cn1cc(-c2ccc(-c3cnc(N)c4ccc(-c5nccn5C)nc34)cc2)cn1 +COCCN1CC2C(C1)C2c1cc(-c2cnc(N)c(Cl)c2)nn1CC1CC1 +CC1CCC2(C)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C(=O)O)C5CCC43C)C2C1C +CS(=O)(=O)c1ccc(-c2cc3c(NC4CCCNC4)ncc(C(N)=O)c3s2)cc1 +CN(c1ccc(NC(=O)NC2CCCC2)cc1)c1ccnc(Nc2cccc(CS(C)(=O)=O)c2)n1 +OC1CCC(Oc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 +NC1CCCN(c2cccc(-c3n[nH]c4cnc(-c5cncs5)cc34)n2)C1 +N#Cc1ccccc1Cn1c(N2CCCC(N)C2)nc2[nH]c(Br)cc2c1=O +COc1ccc(NC2=CC(=O)C(=O)c3ccccc32)cc1 +COCCN1CCC(c2cc(C)c3nc(-c4c(NCCn5cc(Cl)cn5)cc[nH]c4=O)[nH]c3c2)CC1 +CN(C(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1)N(C#N)CCc1ccccc1 +Nc1nc(N2CCN(C(=O)C(Cl)Cl)CC2)nc2nc(-c3ccco3)nn12 +CCc1cc2c(cc1N1CCN(C(=O)C3CNC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +Cc1ccc2c(c1)oc(=O)n2CCOc1ccnc2cc(OCCN3CCOCC3)ccc12 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2ccccc2)CC1 +CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)OC(C)=O +CCOc1c(C#N)cc(Br)cc1CNCCCNc1cc(O)c2ccccc2n1 +CCN1c2ncc(CCOc3ccc(CCC(=O)O)cc3C)cc2C(=O)N(C)c2cccnc21 +Cc1nc(N)c(-c2cnn(C3CCN(C)CC3)n2)nc1-c1cnc2ccccn12 +O=C(Nc1ccc(Cl)nc1)c1ccc(-c2ccccc2)cc1 +COc1ccc(CNc2cc(-c3[nH]c(SCc4ccccc4)nc3-c3ccc(F)cc3)ccn2)cc1 +COC(=O)CCC(C(=O)C=Cc1ccc(O)c(OC(F)(F)F)c1)C(=O)C=Cc1ccco1 +CCOC(Cc1cccc2c1ccn2Cc1nc(-c2ccccc2)oc1C)C(=O)O +N#Cc1ccc(C(=O)Nc2cc(Cl)c(F)c(C3(CF)N=C(N)OC4CC43)c2)nc1 +O=C(Cc1nc(N2CCOCC2)cc(=O)n1-c1ccccc1)N1CCc2ccccc21 +CSCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 +CC(NC(=O)C1(C)CC1)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CC(c1ccc(-c2ccc(F)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +O=C(NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCCN2CCC=N2)N1)c1ccc2ccccc2c1 +Cc1nc(N2CCCCC2)c2c(C)c(C(=O)N3CCN(c4cccc(Cl)c4)CC3)sc2n1 +CN(C)C(=O)C1(Cc2cccc(Nc3cc[nH]n3)n2)CCC(Oc2cccc(Cl)c2F)CC1 +COc1ccc(COc2cccc(-c3ccc4sc(C(=N)N)cc4c3)c2)cc1 +O=C(CNC(=O)c1cccc([N+](=O)[O-])c1)NC1CCN(Cc2ccc(Cl)cc2)C1 +Cc1ccc(C=Cn2nc(C(C)(C)C)cc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CC(C)OC(C)C3)c3ccccc23)cc1 +COc1cccc2cc(C(=O)Nc3ccc(-c4ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc4)cc3)oc12 +O=S(=O)(c1ccc2c(c1)OC1CNCCC21)c1ccccc1-c1ccccc1 +COc1ccncc1-c1ccc(NS(C)(=O)=O)cc1OCC(F)(F)F +Nc1ncc(-c2ccc(C3(c4noc(-c5cnccc5Cl)n4)CCC3)cn2)cn1 +CC1CN(C(=O)c2ccccc2)CCN1S(=O)(=O)c1c[nH]c2c(-n3cncn3)ncc(F)c12 +OC12C3C4CC5C6C4C1C6C(C53)N2Cc1cccc(I)c1 +Cc1cc(N2CCC(N3CCCC3C)C2)ccc1NC(=O)c1ccccc1F +COc1ccc(C(=O)C(=NC2CCCC2)n2ncc(C#N)c2N)c(F)c1 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+N#Cc1c(N)nc(NCCCC2CCN(Cc3ccccc3)CC2)c(C#N)c1-c1ccccc1 +CC(NC(=O)C1(NC(=O)C(F)(F)F)CC1)c1ccc(-c2cccc(F)c2-c2nnn(C)n2)cc1F +COc1cccc(CO)c1C(=O)N1CCC2CN(c3cnc4ccccc4n3)C2C1 +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Nc2ccncc2)N2C1=NC1CCCC12 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(C(C)C)C(=O)C4)ncn3)c2c1 +O=C(O)c1cccc(-c2ccc3c(c2)C(=NNc2nc4ccccc4s2)CCN3)n1 +CCCCCN(CCCCC)c1ccc(C=C(C#N)C(=O)O)cc1 +COc1cc(Nc2nc3c(c(COC4CCCC4)n2)COCC3)ccc1-n1cnc(C)c1 +O=S(=O)(O)Nc1ccc(-c2nc3ccccc3s2)cc1Cl +Cc1cc(CNC(=O)c2cc(-c3ccc(OCc4ccccc4)cc3)n(C)n2)ccc1OC(C)(C)C(=O)O +CN1CCN(c2nc(COC(c3ccc(C#N)cc3)c3cncn3C)ccc2C#N)CC1 +CCNc1cccc2c(S(=O)(=O)Nc3ncc(Br)nc3OC)cccc12 +NC1CCC(Nc2cc(-c3ccc(F)c(NCC4CCOCC4)n3)c(Cl)cn2)CC1 +CCOC(=O)C1=C(C)NC(C[S+]([O-])c2ccccc2C)=C(C(=O)OCC)C1c1ccccc1C(F)(F)F +CCC(=O)NC1c2cncc(-c3ccc4c(c3)CCC(=O)N4C)c2CCC1F +COc1ccc(CCNc2nc(N)c3nc(-c4ccco4)sc3n2)cc1 +CCCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1C +COc1ccccc1-c1nc2c(C(N)=O)cccc2[nH]1 +CCn1c2ccccc2c2cc(S(=O)(=O)Nc3ccc(OC)cc3OC)ccc21 +O=C(Cc1ccccc1)NC(=S)Nc1ccc(Oc2ccnc3cc(C(=O)N4CCOCC4)sc23)c(F)c1 +Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1Br +CNc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 +O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(N2CCCNC2=O)CC1 +CC(C)n1c(CCC(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(N)=O +CN1CCN(c2cc(N(C)S(C)(=O)=O)c3nc(C(=O)NCc4ccc(F)cc4)c(O)c(=O)n3c2)CC1 +CCC(NC(=O)N1CC(=NOc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1cccc(C(=O)O)c1 +CC(C)Nc1cc(Nc2ccc3nsnc3c2)ncc1-c1nnc(C(=O)N2CCC(O)C2)s1 +O=C(CC1CC1)NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1 +CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4c(c3)C(CCNC(C)=O)CCC4)cc12 +NC(=O)c1ccc(F)c2c1CC(N(CCc1c[nH]c3ccc(F)cc13)CC1CC1)CO2 +CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(N(Cc2cccc(C#N)c2)c2ccc(C#N)cc2)CC1 +CC(=O)NCCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1N1CCN(C)CC1 +COc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCn1ccnc1[N+](=O)[O-] +O=C(CCS(=O)(=O)c1ccc(Cl)cc1)Nc1nc(-c2ccncc2)cs1 +CCC1COC(c2ccc3c(C(=O)NCc4ccc(F)c(F)c4)c(C(C)C)n(Cc4ncco4)c3c2)=N1 +CCCc1nc2c(n1Cc1ccc(-c3ccccc3S(=O)(=O)Nc3onc(C)c3C)c(CO)c1)C(=O)CCCC2 +CC[n+]1c(C=Cc2ccc(F)cc2)ccc2ccccc21 +CCC(=O)N1CCc2nc(-c3cc(C(=O)N4CCC(c5ccc(C#N)cc5)CC4)c(C)cc3C)[nH]c2C1 +COc1cnc2c(NCc3nnc4ccc(-c5ccc(F)c(Cl)c5)cn34)ccnc2c1 +CC12CC(O)C(C)(O1)C1C(=O)N(c3ccc(C#N)c(I)c3)C(=O)C12 +Cc1cccc(-n2c(SCc3cc(=O)n4ccsc4n3)nc3ccccc32)c1 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(Cl)cc1 +c1cc(-c2nnc[nH]2)c2nc(N3CCOCC3)c3ccsc3c2c1 +Cc1ccccc1-c1ccc(-c2nc(-c3ccc4c(c3)CN(CCC(=O)O)CC4)no2)cc1C(F)(F)F +CC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cc(Cl)cc(C(F)F)c1 +Cc1ccc(N(CC(=O)Nc2cccc(Cl)c2C)S(=O)(=O)c2ccccc2)cc1 +O=c1ccc2c([nH]1)CCCC2NCCCCCCCCCCNC1CCCc2[nH]c(=O)ccc21 +FC(F)(F)c1ccc(-c2cnc(Nc3cccc4cnccc34)o2)cc1 +CC1CN2c3c(cc4c(N5C(=O)OCC5C5CCOCC5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +COCCc1sc[n+](CCOc2ccc(-c3ccc(OCC[n+]4csc(CCOC)c4C)cc3)cc2)c1C +O=C(N1CCCC1)N1Cc2c(-c3ccc(F)cc3)ncn2-c2ccccc21 +CC(C)CC(O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)C2CCCNC2)CC1 +O=C(O)COc1cccc2c1CCC(Cn1ncc(-c3ccccc3)c(-c3ccccc3)c1=O)C2 +Nc1ccccc1NC(=O)CCCCCNC(=O)c1cc2ccccc2cn1 +CCCc1nc(CN2CCN(c3ccccn3)CC2)c(C=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(C)OC(=O)C(C)NP(=O)(COC1C=C(F)C(n2cnc3c(N)ncnc32)O1)Oc1ccccc1 +Nc1ccc(-c2c[nH]c3cc(-c4cncc(OC5CCC(N)CC5)n4)ccc23)c(F)n1 +c1ccc(CN2CCN(c3cccc4[nH]ccc34)CC2)cc1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NC1CCCN(S(C)(=O)=O)C1 +CCNc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NC1CCC(C(C)(C)O)CC1 +Nc1n[nH]c2cc(-c3ccc(C(=O)O)cc3)nc(-c3ccc(Oc4ccccc4)cc3)c12 +Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)sc4n3)c2)n(C)n1 +CN(CCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N1CCCC1)CC2)S(=O)(=O)CC1CC1 +O=C(CCCCCCCSc1nc(=O)c(Cc2cncnc2)cn1CCc1ccccc1)c1ccc(Cl)cc1 +Fc1ccc(C2(CCNCc3ccccc3)CCOC3(CCCCC3)C2)cc1 +CC(=O)OCC1OC(NS(=O)(=O)NO)C=CC1OC(C)=O +COc1cc(Nc2nc3c(s2)CCCC3c2ccccc2)ccc1-c1nnc(C)o1 +CC1CN(C(=O)C(NC(=O)c2ccc(N3CCN(C)CC3)cc2)C2CCCC2)C2C(=O)COC12 +O=C1c2c(ccc(O)c2O)CN1Cc1ccc(F)c(F)c1 +Cc1c(Cc2ccccc2)nc2cc(F)cc(F)c2c1N1CC(C)(C)c2ncc(N3CCOCC3)cc21 +O=C(Nc1cc(C2CCN(C3CCC3)CC2)nn1-c1ccc(Cl)cc1F)c1cnn2cccnc12 +Cc1ccnc(-n2nnc3c2CCN(C(=O)c2cccc(Cl)c2Cl)C3C)c1 +CC(Nc1nccc(N(CC2CCN(S(N)(=O)=O)CC2)C(=O)c2ccc3c(c2)CCO3)n1)c1ccccc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCC(F)(F)F)nc23)N1 +CCCCc1nc(C=Cc2cccc(C(CCc3ccccc3C(C)(C)O)SCC3(CC(=O)O)CC3)c2)ccc1C +Cc1ccc(C2=NC(=O)C(=Cc3cccs3)S2)cc1 +Cc1cccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)n1 +Cc1cccc(Cl)c1-c1nnc2c(C)nc3cnccc3n12 +Nc1ncc(-c2cn3c4c(nc3c(N3CCOCC3)n2)CCN(C(=O)NC2CCCCC2)C4)cn1 +N#Cc1ccc(Oc2ccc3nc(C(=O)NC4CCN(Cc5ccccc5)C4)ccc3c2)cc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C(F)(F)F)n2c1COCC2)c1ccccc1 +Fc1ccccc1-c1cn2ccnc2c(NCc2ccncc2)n1 +O=C(O)CC(NC(=O)C(c1ccccn1)n1cccc(NC(=O)c2ccc3ccccc3c2)c1=O)C(=O)COc1ccccc1 +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cocn1 +CC(C)CCCCC(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)C1(CO)CO1 +CC(=O)N1C(C)(C)C=C(c2nc3c(C(N)=O)cccc3[nH]2)C1(C)C +c1ccc2c(c1)CCCCC2CCN1CCN(c2cccc3c2OCCO3)CC1 +CCOCCOCCOc1cccc(N2CCN(CCCCc3c[nH]c4ccc(C(N)=O)cc34)CC2)c1C#N +O=C(NC(Cc1ccccc1)C(=O)O)c1ccccc1-c1ccccc1C(=O)NC(Cc1ccccc1)C(=O)O +O=C(NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1cc2ccccc2[nH]1 +O=C(NCCCCCCCNc1c2c(nc3ccccc13)CCCC2)c1cc2ccccc2oc1=O +O=C(C=Cc1cc(Cl)ccc1-n1cnnn1)NC1CCCCCNc2cc(NC(=O)OCC3CCCO3)ccc2-c2c[nH]c1n2 +CN1CCN(c2ccc(Nc3nc4c(NCc5cccc(N(C)S(C)(=O)=O)c5)cccn4n3)cc2)CC1 +FC(F)(F)c1ccccc1C1CCN(c2cc(N3CCCC3c3nc4cc(Cl)c(Cl)cc4[nH]3)ncn2)CC1 +COc1ccc(-c2nnc(C(=O)N3CC(Oc4ccc(CN5CC6(CCCO6)C5)cc4)C3)o2)cc1 +O=C(CCCNC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc21)NO +CCCc1ccc(S(=O)(=O)N2CCN(c3ncccc3C(F)(F)F)CC2)cc1 +O=S(=O)(O)OCC1CNCC(OCc2ccc3ccccc3c2)C1c1ccc(OCCCOCc2ccccc2)cc1 +O=C(CP(=O)(O)O)NCCCc1cccc(Oc2ccc(Cl)c(Cl)c2)c1 +Cc1ccc(CN(C(=O)c2ccc(O)cc2O)c2ccc(-c3nc4ccccc4cc3C)cc2)cc1 +OCCN(CCO)c1nc(N2CCc3ccccc3C2)c2nc(N(CCO)CCO)nc(N3CCc4ccccc4C3)c2n1 +Nc1ncc(-c2ccc(-c3ccc(C(F)(F)F)cc3S(N)(=O)=O)cc2F)cn1 +O=C(CC1CCCCC1)N1CCC(c2nc(-c3cccs3)no2)CC1 +Cc1cccc(Cl)c1Nc1nc2ccc(N(C)CCO)nc2n2cncc12 +CCN1CCN(Cc2nc3ccc([N+](=O)[O-])cc3c(=O)n2-c2ccccc2)CC1 +COc1ccc(CN2CCN(c3c(C)c(C)c4c(c3C)CC(C)(C)O4)CC2)cc1 +O=C(NC1CC2CCC1C2)C1(NS(=O)(=O)c2cccc(Cl)c2)CC1 +C=CC1(C)CC(=O)C2(O)C(C)(O1)C(O)C(OC(=O)NCCC(=O)OCC)C1C(C)(C)CCC(O)C12C +CNc1nn2c(OC)cc(-c3cccnc3)nc2c1S(=O)(=O)c1ccccc1 +NC(COc1cncc(-c2ccc3[nH]c(=O)oc3c2)c1)Cc1c[nH]c2ccccc12 +CCCOC(=O)C1=CN(C(=O)c2ccc(F)cc2)CCc2c1[nH]c1ccccc21 +COc1cc2[nH]c(C)c(-c3ccc(C(C)=O)cc3)c(=O)c2cc1Cl +CCOc1ccc(-c2c(C)c3cc(O)ccc3n2Cc2ccc(OCCN3CCCCCC3)cc2)cc1 +CCC(C)Oc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc(N)c1C=O +CS(=O)(=O)c1cnc(OC2CCC(OC3CCN(C(=O)C4(C(F)(F)F)CC4)CC3)CC2)cn1 +CCCCCCC(=O)OCC(C)(C)CC1=C(O)C(=O)c2ccccc2C1=O +COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2c(c1)COC2=O)Cc1ccccc1 +CC(=C1C(=O)Nc2ccc(NC(N)=O)cc21)c1cc(CNC(=O)c2ccncc2)c[nH]1 +O=S(=O)(Nc1ncc(F)s1)c1ccc2c(-c3ccc(C(F)(F)F)cc3C3CCNCC3)cccc2c1 +Cc1ccc2c(c1)C(=Nc1ccc(C)c(N=C3C(=O)Nc4ccc(C)cc43)c1)C(=O)N2 +COc1ccc(Br)cc1N1CCN(Cc2ccc(F)cc2Cl)C(=O)C1=O +COc1ccc2cc(-c3cncc(C(C)O)c3)ccc2c1 +CC(C)Oc1cc(NC(=N)c2ccccn2)ccc1-c1ccc(-c2ccc(NC(=N)c3ccccn3)cc2OC(C)C)o1 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+CC(C)c1ccc(CNc2ccc3c(c2)ncn3-c2ccc(OCCc3ccccc3)cc2)cc1 +CN(Cc1ccc2nc(N)nc(N)c2n1)c1ccc(C(=O)C(F)(F)F)cc1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1c(-c2ccc(OC)c(OC)c2)nc2sccn12 +CCCn1c(CN2CCN(c3ncc(Cl)cn3)CC2)nc2ccccc21 +O=C(Nc1ccccc1)c1cnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1 +Cc1cc(OCCCNCCc2c[nH]cn2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 +O=c1n(Cc2ccncc2)nc(-c2ccnc(NC3CCCCC3)c2)n1-c1ccc2ccccc2c1 +COc1ccccc1NC(=O)Nc1nn(-c2ccccc2)c(=O)c2ccccc12 +CNc1nc(Nc2c(C)cc(C)cc2C)nc(NC2CCN(Cc3ccc(C#N)cc3)CC2)n1 +C=CCN1C2CCC1CC(=C(c1ccc(C(=O)NCC)cc1)c1cccc(OC)c1)C2 +COCCN1CCN(c2nc(N)c3ncnc(Nc4cc(C(=O)Nc5cc(C(C)(C)C)n[nH]5)ccc4C)c3n2)CC1 +CC(NC(=O)CC1SC(c2ccc(Cl)cc2Cl)N(CC(=O)NCCCN2CCOCC2)C1=O)c1cccc2ccccc12 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2C +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN2CCN(C)C2=O)cc1 +CCN(CC)C(=O)c1ccc(C(=Nc2ccccc2)N2CCCN(CCc3ccccc3)CC2)cc1 +NCC(c1ccc(C(F)(F)F)cc1)N1CCN(c2ncnc(N)c2OCC(F)(F)F)CC1 +Nc1ncnc2c1c(-c1ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc1)cn2C1CC(CN2CCCC2)C1 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+CCOc1ccc(OCC(=O)O)cc1CC(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C +O=C1NC(=O)c2c1c1c(ccc3cc[nH]c31)c1[nH]c3ccccc3c21 +Oc1c(Oc2cc(Cl)c(Cl)c(Cl)c2O)cc(Cl)c(Cl)c1Cl +Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnn(CC(F)F)c1N1CCC(N)CC(F)(F)C1 +O=C1NC(=O)C(=Cc2cc(-c3ccccc3)c(O)c(-c3ccccc3)c2)S1 +CCC(C)(C)c1nn(CCO)c2c1N=C(c1ccc(-n3ccnc3C)cc1)CNC2=O +CN1Cc2c(C3=CCCN(CC(=O)N4CC(O)C4)CC3)[nH]c3nccc(c23)-c2cc(F)ccc21 +CCC1C(C)C(Nc2ccccc2)c2ccccc2N1C(=O)c1ccc(Cl)cc1 +CN(Cc1ccc(F)cc1)C(=O)n1cnc(S(=O)(=O)C2CC3CCC2C3)n1 +CCN1CCN(C(=O)OC2(C3CCCC(c4cc(F)cc(F)c4)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1 +NCCCCCNC(=O)Cn1c(-c2ccc3ccccc3c2)nc2ccc(-c3ccccc3)cc2c1=O +CCN(CC)CCCNC1=C(Cl)C(=O)c2ccccc2C1=O +CC12CCC=CC1=CCC1C2CCC2(C)C(O)CCC12 +CC1CC(N)CC(c2ccncc2NC(=O)c2cccc(-c3cc(O)ccc3F)n2)C1 +N#Cc1ccc(C(NC(=O)C2CCC(N3CCOCC3)CC2c2ccc(Br)cc2)c2ccc(Cl)cc2)cc1 +CC1CC(N)CN(c2ccncc2Nc2cccc3cnc(-c4c(F)cccc4F)nc23)C1 +CCCCCc1cc2c(s1)CC1c3cc(O)c(OC)cc3CCN1C2 +CN(C)c1ccc(-c2cn(CCCCCCCCC(=O)NO)nn2)cc1 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+O=C(Nc1ccc(Cl)c(Cl)c1)Nc1cc(C(F)(F)F)ccc1Oc1ccc(Cl)cc1Cl +Cc1cc(CCC#N)cc(C)c1Oc1ccc(N)c(Nc2ccc(C#N)cc2)c1 +Cc1cc(CCC#N)cc(C)c1Nc1ccnc(Nc2ccc(C#N)cc2)n1 +O=C(CCCO[N+](=O)[O-])Oc1ccc(C(=O)Oc2ccc(-c3cc(=S)ss3)cc2)cc1Cl +CC(C)(C(=O)O)N1CCC(C(=O)NC2CCN(Cc3cccc(Oc4ccccc4Cl)c3)CC2)(c2ccccc2)C1 +CC(C)CCC1=C(C(=O)O)C(c2ccc3c(c2)OCO3)Oc2ccc(OC(C)C)cc21 +COc1ccc(NC(=O)C(=O)c2c[nH]c3ccccc23)cn1 +CC(C)(C)OC(=O)Nc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)cc1 +Cc1ncc(-c2ccc3c(c2)C(=O)CC2(CCN(C(=O)c4cc(C)c5[nH]ncc5c4)CC2)O3)o1 +O=C(O)c1cc(-c2ccc(Cl)nc2)nc2c1cnn2Cc1ccncc1 +CC(O)(C(=O)Nc1ccc(C(=O)N2CCCCC2)cc1Cl)C(F)(F)F +COCCNC(=O)c1cccc(Cn2[nH]c(=O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)c1 +CC1(F)C(O)C(CO)OC1n1cc(-c2ncco2)c2c(N)ncnc21 +O=CC(Cc1ccccc1)NC(=O)c1ccccc1COc1ccccc1 +CCN(CC)CCOc1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1OC2 +Cc1ccc(S(=O)(=O)Nc2c(C(=O)NC(C)C(C)(C)C)c(C(F)(F)F)nn2-c2ccccc2)cc1 +CC(C)C(=O)N(O)C(C)c1ccc(OCc2ccccc2)cc1 +N#Cc1sc(NCCNc2nc(-c3ccc(Cl)cc3Cl)cn3nc(C(=O)NCC(=O)O)cc23)nc1N 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+Cc1cc(C)n(CCCCCC2(C)COC(c3nc(-c4ccccc4)c(-c4ccccc4)[nH]3)OC2)n1 +CCNC(=O)c1ccc(Cc2c(C(=O)OC)n(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1 +CCc1ncn(CCC(C(N)=O)(c2ccccc2)c2ccccc2)c1CC +CNC(=O)c1ncn2c1COc1c(CCN3CCN(c4cccc5nc(C)ccc45)CC3)cccc1-2 +Nc1ncnc2c1C(=O)N(c1ccc(-c3ccccc3Cl)cc1)CCO2 +CN1CCN(C(=O)c2cc3cc(Cl)cc(F)c3[nH]2)CC1 +CCCCCc1ccc(CN(CCN(CCCC)CCCC)Cc2ccc(OCc3ccccc3)cc2)cc1 +CC(C)C(=O)NC(c1nnc(CNS(N)(=O)=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 +CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc21 +CCOc1cc2ncc(C#N)c(Nc3cc(Cl)c(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C +CC(CC(=O)O)(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +CNC(=O)C1=CC(=C2C(=O)c3ccccc3C(C)(CCC(C)(C)C)C2=O)Nc2ccc(NS(C)(=O)=O)cc21 +CC1C(O)C(Cc2ccccc2)C(=O)N1c1ccc(C#N)c(Cl)c1 +CCN1C(=O)CC2C3CCc4cc(OS(N)(=O)=O)ccc4C3CCC2(C)C1=O +O=C(Nc1ccc(C2CNCCO2)cc1)c1cnn(-c2ccc(F)cc2)n1 +Cc1csc(NC(=O)C2c3ccccc3C(=O)N(CC(C)C)C2c2cccs2)n1 +O=C(O)COCC1CCC(COC(=O)N(c2cccc(F)c2)c2ccc(Cl)c(F)c2)CC1 +CSc1ccc(NC(=O)NC(Cc2ccccc2)C(=O)N2CCCCC2)cc1 +CCc1oc(-c2ccccc2)nc1C(=O)Nc1ccc(N2CCOCC2)nc1 +O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(COC3COC3)ccc1-2 +CCc1c2c(nc3ccc(Cl)cc13)-c1cc3c(CO)cccc3c(=O)n1C2 +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccsc3)cn2CCN2CCC2)CC1 +Cc1ccc(NC(=O)c2cccn3c(=O)cc(N4CCOCC4)nc23)cc1 +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +CCOc1c(Br)cc(C2C(C(=O)OC)=CN(C)C=C2C(=O)OC)cc1OC +COc1ccc(Cc2nccc3cc(OC)c(OCCF)cc23)cc1F +COc1ccc2[nH]cc(CCNC(=O)c3cc[n+](Cc4ccc(OC(=O)N(C)C)cc4)cc3)c2c1 +CC(=O)NC(C)C#Cc1cnc(Oc2ccc(SC(C)C)cc2)s1 +CSc1sc(-c2cc[nH]n2)c2c1C(=O)NC(C(F)(F)F)C2 +O=C(C1CC1c1ccc(N2CCCC2)cc1)N1CCN(C2CCC2)CC1 +FC(F)(c1ccccc1)c1nnc(-c2sc3ccccc3c2OC2CCNCC2)o1 +O=C(c1ccc(N2CCN(C(=O)c3ccccc3Cl)CC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +COc1ccc(-n2nnnc2C(F)(F)F)cc1CNC1CCN(C(C)=O)CC1c1ccccc1 +Cc1nc(C#Cc2ccc(C3CC4CCC3C4)nc2)cs1 +CN1CC2(CCN(CC(O)Cc3ccc(Br)cc3)CC2)c2ccccc21 +O=C(NCCc1ccc(F)cc1)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CC(C)NC1=NNC(=O)C1=Cc1cc2ccccc2[nH]1 +Cc1ccccc1SC1=C(O)OC(c2ccccc2)(c2ccccc2)CC1=O +COc1ncccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +NC1CCCN(c2nc(-c3n[nH]c4cnc(-c5cccnc5)cc34)ccc2C2CC2)C1 +CC(C)=CCCn1cc(CC(P(=O)(O)O)P(=O)(O)O)nn1 +O=C1OC2(CCC(N3CCC(Cc4cc(F)ccc4F)CC3)CC2)c2ccc3c(c21)OCCO3 +COc1ccc(CCN(C)CCCOc2ccc(S(=O)(=O)c3c(C(C)C)n(C)c4ccccc34)cc2)cc1OC +CCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2c1)c1ccc(F)cc1Cl +Cc1ccc(N2CCC(F)(F)CC2)nc1C(=O)Nc1c(C)cc(C(=O)O)cc1C +Cc1ccc(-c2cc(CC(C)(C)C)[nH]n2)cc1S(=O)(=O)N1CCOCC1 +NCC1OC(OC(CNc2ccc(C3CCCCC3)cc2)C2CC(O)C(n3ccc(=O)[nH]c3=O)O2)C(O)C1O +CCn1cc(Nc2ncc(C3CC3)c(NCCCNC(=O)C3CCC3)n2)cn1 +CCN(CCO)CCOc1ccc(-c2cc3c(NCCc4ccc(NC(=O)Nc5ccccc5)cc4)ncnc3o2)cc1 +O=C(NCCCCCCS(=O)(=O)N(CCN1CCOCC1)CC1CCCCC1)Nc1ccncc1 +COc1ncc(C(CO)Nc2ncnc3c2CN(c2ccc(C)cc2C#N)CC3)cn1 +COc1ccc(-c2cn(CCCCCC(=O)NO)nn2)cc1 +COc1ccc(-c2noc(C)c2C(=O)N=C(N)NCc2cc(Cl)c(N)c(Cl)c2)cc1 +NC(Cn1c(=O)c(-c2cccc(O)c2F)cn(Cc2c(F)cccc2F)c1=O)c1ccccc1 +CC(COC(C)(C)C)Oc1ccc(S(C)(=O)=O)cc1-c1cn(C)c(=O)c2[nH]ccc12 +COc1ccc(C2=NN(Cc3ccc(CN(C)C)cc3)C(=O)C3CC=CCC23)cc1OC +CCCCCCOc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O +CC=CC=CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 +CN(c1ccc2[nH]ccc2c1)c1c(C#N)cncc1C=Cc1ccccc1 +O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2cc(Cl)ccc2c1 +N=C(N)c1cccc(C2CN(Cc3ccc(-c4ccccc4S(N)(=O)=O)cc3)CC2C(N)=O)c1 +O=C(c1ccccc1)c1ccccc1NC(Cc1ccc(OCCOc2ccc([N+](=O)[O-])cn2)cc1)C(=O)O +Cc1[nH]c2cc(S(C)(=O)=O)ccc2c1Cc1ccc(Cl)cc1 +Cn1cc(NC(=O)c2cnn3ccc(N)nc23)c(-c2cc(Cl)ccc2Cl)n1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2ccsc2)cc1Cl +[C-]#[N+]c1ccc(C2(O)CCN(C(=O)C3CCCCC3NC(=O)c3cccc(C(=O)O)c3)CC2(C)C)cc1 +CCN1CCC(CNCc2ccc(C(=O)Nc3cc(-c4ccccc4)ccc3O)cc2)CC1 +CN1CCCCC(Oc2ccc3c(c2)C(=NO)c2ccccc2-3)C1 +CCCCCCCC(C(=O)CS)C(=O)NC(CC(C)C)C(=O)Nc1ccccc1 +CC(C(=O)Nc1ccc(C2CCNC2)cc1)c1cccc(C(=O)c2ccccc2)c1 +CCNc1nc2c(SCc3ccccc3)ncnc2n1C1OC(CO)C(O)C1O +O=c1ccc(-c2ccc(S(=O)(=O)Nc3cc4c(=O)[nH]ccc4cc3F)s2)c[nH]1 +c1ccc(CNCc2ccc(CNCc3ccccc3)cc2)cc1 +COC12CCC3(CC1C(O)CCC1CCCC1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +O=C1Cc2c([nH]c3ccc(I)cc23)-c2ncccc2N1 +CC(C)(C)C(=O)Oc1ccc(Cc2ccc(OC(=O)C(C)(C)C)cc2)cc1 +COCCN1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 +COc1cc(-c2ccncc2)cc(C(C)C#Cc2c(C)nc(N)nc2N)c1 +CC(=Cc1cc(O)cc(O)c1)c1ccc(C(F)(F)F)cc1 +Cc1c(CC(=O)O)c2cc(F)ccc2n1S(=O)(=O)c1cccc(F)c1 +Cc1sc2ncnc(SCC(=O)NS(C)(=O)=O)c2c1C +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(F)c(CNCC4CC4)c3)nc2n1 +COc1cccc(-c2ocnc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 +O=C(c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1)N1CCN(c2cccc(Cl)c2Cl)CC1 +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NCCc1ccccc1 +COCC(NC(=O)Nc1cc2[nH]nc(N3CCC(OC)CC3)c2cn1)c1ccccc1 +O=P(O)(O)OCC1OC(n2cnc3c(-c4ccc(O)cc4)ncnc32)C(O)C1O +CC1(O)CCC2CCC(C(=O)NCc3ccc(C(=N)N)cc3)N2C1=O +COc1ccc2[nH]c3nc4ccnc(NCCCN(C)CCCN)c4c(C)c3c2c1 +CN(CC=CC#CC(C)(C)C)Cc1cccc(OCC(C)(C)OCc2ccsc2)c1 +CN1CCCCCNC(=O)C2=Cc3ccc(Cl)cc3-c3c(C4CCCCC4)c4ccc(cc4n3C2)C(=O)NS1(=O)=O 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+CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2ncn(CCc3ccc(F)cc3)c12 +CCCCN(C1c2cc(C(=O)NCCc3ccccc3)ccc2OC(C)(C)C1O)S(=O)(=O)c1ccc(CC)cc1 +CCOc1ccc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c(F)c1F +Nc1nnc(-c2ccc3[nH]cc(-c4cccc(N5CCOCC5)n4)c3c2)s1 +N=C(N)c1ccc2oc(C(=O)NCCC(=O)NCC(NS(=O)(=O)c3ccccc3)C(=O)O)cc2c1 +CC(C)N1CCN(C(=O)OC2CCN(c3ccc(C(F)(F)F)cn3)C2)CC1 +CC(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1 +O=C(C(=Cc1ccc([N+](=O)[O-])cc1)S(=O)(=O)Cc1ccccc1)c1ccc(Cl)cc1 +Nc1cnc(-c2ccc(C3CCC3)c(OCc3cccc(F)c3)c2F)cn1 +COc1cccc(Nc2nnc(-c3c(NCc4ccncc4)ncn3C)o2)c1 +O=C(c1ccc(F)c(O)c1)c1nc2ccc(O)cc2s1 +COc1cccc(NC(=O)C2CC3CC3N2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC2CC2)cn1 +COc1ccc(-c2c[nH]c(C(=O)c3cc(OC)c(OC)c(OC)c3)n2)cc1 +COC(=O)C(CCSC)NC(=O)C1CC(Oc2ccccc2)CN1CCCCC(N)CS +Cc1cc(C(C)(C)NC(=O)c2cccc(-c3cccc(Cl)c3)n2)on1 +CN(C)C(=O)C(=O)N(C)C1CCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O +CC(C)CC(N)C(=O)NS(=O)(=O)OCC1OC(c2nc(-c3ccc(Oc4ccccc4)cc3)cs2)C(O)C1O 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+S=C(NN=C(c1ccccn1)c1ccccn1)Nc1ccccc1 +OCC1(NCc2cccc(-c3ccc(C(F)(F)F)cc3C(F)(F)F)n2)CCCC1 +O=[N+]([O-])c1ccccc1CN1CCN(c2cc(N3CCCC3)nc(N3CCCC3)n2)CC1 +CN1Cc2c(C(=O)OC(C)(C)C)ncn2-c2ccsc2C1=O +O=C(O)C1CCC(OCC2CC(F)CN2C(=O)Cc2cc(Cl)c(Nc3nc4cc(F)ccc4s3)cc2F)CC1 +O=C(Nc1cccnc1-c1cccc(Cl)c1)c1cnn2cccnc12 +CN1C(=O)c2[nH]c(Cc3ccc(-c4ccccc4)cc3)nc2N2CC3(CCCC3)N=C12 +O=C(c1ccc(O)cc1)c1ccc(Sc2cccc(O)c2)s1 +O=C(O)CCC=CCC1COC(c2cccc(OCCOc3cc(C(=O)O)ccc3OCCn3ccnc3)c2)OC1c1ccccc1O +CCCCC(CC)CNC(=O)c1ccc2c(c1)c(Cc1ccc(C(=O)NS(=O)(=O)c3ccccc3C)cc1OC)cn2C +COc1cccc(N2CCN(C(=O)N3c4ccccc4Oc4cc(C#N)ccc43)CC2)c1 +CC1CCCC(C)N1C(=O)c1ccc(C(=C2CC3CCC(C2)N3CCc2ccccc2)c2ccccc2)cc1 +Cc1cc(C(F)(F)F)nn1-c1ccc(NCc2c(F)cccc2F)nc1 +O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccc2ccccc12 +CN1CCN(c2cc(-c3cccnc3)nc(-c3ccncc3)n2)CC1 +CC1(C2CCCC2)Cc2cc(OCCCCc3nn[nH]n3)c(Cl)c(Cl)c2C1=O +CC1Cc2c(nnn2-c2ncccc2F)CN1C(=O)c1cccc(C(F)(F)F)c1Cl +CNC1CCC(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1 +CC(C)Oc1cc2c(-c3cc(N4CC(O)C(N(C)C)C4)ncn3)n[nH]c2cc1F +CCCC12CCC(C(C)=O)=C1c1c(cc(OCC(=O)O)c(Cl)c1Cl)C2 +COCC(Oc1cc(CC2C[S+]([O-])CC(NCc3cccc(C(C)(C)C)c3)C2O)cc(F)c1N)C(F)(F)F +Cc1cccc(N2CCN(CC(O)CNC(=O)c3nc(C)n(-c4cccc(Cl)c4)c3C)CC2)c1C +CCN(CC)CCCCCOc1ccc2c(=O)c3ccc(OCCCCCN(CC)CC)cc3oc2c1 +O=C(Nc1cccc(C(F)(F)F)c1)c1ccc(CO)c(-c2ccnc(N3CCOCC3)c2)c1 +c1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)c1c-2sc2ccccc12 +CC(=O)NC1CSC(=O)C(Cc2ccccc2)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CO)NC1=O +N#CC1CC(C(=O)NC2CCC2)CCC1n1cc(C(N)=O)c(Nc2ccc(Cl)cc2)n1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1c2cc(F)c(F)cc2-c2n[nH]cc2C1C1CC1 +CNC(=O)C12CC1C(n1cnc3c(NCCc4ccccc4)nc(C#Cc4ccccc4)nc31)C(O)C2O +COc1cccc2cc(C(=O)NCCCCCCNc3c4c(nc5ccccc35)CCC4)oc12 +CCNC(=O)N1CCN(Cc2cc(Nc3nc(C)cn4c(-c5cn[nH]c5)cnc34)sn2)CC1 +O=C(CCOc1ccccc1)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +Cc1cccc(CC(Nc2ccc3c(c2)C(=O)OC3)C(=O)NC(C#N)COCc2cccc(C(=O)O)c2)c1 +COc1cc(C)nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)n1 +CCc1ccc(CNC(=O)C2CCN(C(C)c3cccc4ccccc34)CC2)cc1 +CN(C)CCCC1(c2ccc(F)cc2)OCc2c(I)cccc21 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(OC4COCCC4O)ccc3Cl)nnc12 +COc1ccc(Cc2cc(C3CCN(C(=O)c4ccc(OC)c(OC)c4)CC3)nc(N)n2)cc1 +COc1cc(-c2cc(C(=O)O)c3c(ccc4ccccc43)n2)ccc1OCCCC#N +Cc1ncc(C(CNC(=O)c2cccc(Cl)c2Cl)N2CCOCC2)cn1 +CC(C(=O)Nc1ccc(CC2=NNNN2)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 +COc1ccc(P(=O)(OCCF)N2Cc3ccccc3CC2C(=O)NO)cc1 +CC(=O)Nc1cccc(C(=O)NCC(O)CN2CCc3ccccc3C2)c1 +N#CNC(=NCc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +Cc1ccc(C)n2nc(CCc3nc(-c4cscn4)cn3C)nc12 +COc1ccccc1-c1nc(NCc2ccc(-c3cccnc3)cc2)c2ccccc2n1 +O=S(=O)(Nc1c(Cl)c(Cl)c(NS(=O)(=O)c2ccccc2)c(Cl)c1Cl)c1ccccc1 +Cc1ccc(Cl)c(CNC(=O)Cc2c(C)n[nH]c2C)c1F +Cc1ccsc1C(=CCCN1CCC=C(C(=O)O)C1)c1cccs1 +CCOC(O)=C1C(COCCn2c(C)nc(C)c2C)=NC(C)=C(C(=O)Nc2ccccc2)C1c1ccccc1Cl +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)NCCN4CCCC4)c4ccc(C)cc34)cc2)c1C +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3cccc(Cn4nnc5ccccc54)c3)n2)CC1 +Cn1nc(C(C)(C)C)c(C#N)c1-c1nc2cc(-c3ccccc3F)ncc2[nH]1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cnn(Cc4ccccc4)c3)c(C(=O)O)n1)CC2 +O=C(Nc1ccc(C2=CCN(C(=O)C3CCCO3)CC2)cc1)N1Cc2ccccc2C1 +COc1ccc(-c2ccc3c(c2)ncn3-c2ccccc2)cc1 +CC(C)C(NC(=O)Nc1ccc(C(=O)O)cc1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)F)C(C)C +COc1cccc(F)c1CNC(=O)Nc1cc2[nH]nc(OC)c2c(CO)n1 +O=S(=O)(c1ccc(Cl)s1)c1cn(C2CCCNC2)c2ncccc12 +OC1CN(CCCOc2ccccc2)CCc2cc(OCc3ccccc3)ccc21 +O=C1C(=Cc2ccc(O)cc2)COc2ccc(Br)cc21 +COc1ccc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +CCCCc1nc2cc(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 +COc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)c(OC)n1 +CCNC(=O)Nc1nc2cc(-c3cncnc3)c(=O)n(C(C)C)c2s1 +O=C(O)c1cccc(-c2cccc(NCCNCC(O)c3cccc(Cl)c3)c2)n1 +Oc1nc2ccc(C#CCCN3CCC(Cc4ccccc4)CC3)cc2o1 +CCCSCC1c2cccc(O)c2C(=O)C2=C(O)C3(O)C(O)=C(C(N)=O)C(=O)C(N(C)C)C3C(O)C21 +O=C(CCCCCCc1ccccc1)c1ncc(-c2cccnn2)o1 +NC1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 +Cc1ccc(-c2nc(C3CCCC3)nc3c2CCNCC3)cc1 +CCCCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(CCOc3ccccc3)CC2)cc1 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+Cc1ncccc1C(C#N)N1CCN(C(=O)CC(NC(=O)OCC(C)C)c2ccccc2)CC1 +COc1ccc2c(c1)CCC1(CCCCN1CCc1c(C)cc(C)cc1C)C2=O +CCOC(=O)c1ccccc1-c1cnc(Nc2ccc(-c3cnco3)c(OC)c2)o1 +O=C(N1CCc2ncc(C(F)(F)F)cc2C1)C12CCOC1CC(NC1CCOCC1)C2 +CCn1ccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)n1 +CC(O)CN1C(C)CN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCCC3)CNC5=O)nc2)CC1C +O=C(NCc1cccc(OC(F)(F)F)c1)C1c2ccccc2C(=O)N1CCc1ncc(F)cn1 +CS(=O)(=O)Nc1ccc(CCNC(=O)c2ccc(O)c3nc(-c4ccc(Cl)cc4Cl)[nH]c23)cc1 +COc1ccccc1C1C(C(=O)C(C)(C)C)=C(N)C(=O)N1c1ccc(-c2ccon2)cc1 +Clc1cnc(NC2CCC(NC3CCOC3)CC2)cc1-c1nc(NCC2CCOCC2)ccc1Cl +N#Cc1cc2c(Oc3ccc(Cl)cc3OCCn3ccc(=O)[nH]c3=O)cccc2o1 +COc1ccc(NCCNC(=O)C(CC(C)C)NC(=O)c2ccc(OCc3ccccc3)cc2)cc1 +O=c1cc(NC2CCN(Cc3ccc4ocnc4c3)CC2)c2cc(Cl)ccc2o1 +COc1cc2c(cc1OC)C(=O)N1C=C(c3ccc(C(N)=O)cc3)CC1C=N2 +Cc1ccc(NC(=O)C(=O)c2c[nH]c3ccc(C)cc23)cc1 +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5ccc(F)cc5)no4)cc3)cc2)C(=O)NC(=O)NC1=O +O=C(Nc1ccc2c(c1)NC(=O)C(N1CCOCC1)C2)NC1CCC(c2ccccc2)C1 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+COc1cc(C(=O)c2sc(-c3cccc(Cl)c3)nc2N)cc(OC)c1OC +COc1nc(N)nc2c1ncn2C1OC(COP(=O)(NC2CC2)NC(C)C(=O)OCC(C)(C)C)C(O)C1(C)O +COc1ccc(C2C(=O)N(C3CCN(C(=O)n4cncn4)CC3)C2c2ccc3c(c2)OCO3)cc1 +CCOC(O)=C1C(COCCNc2cc(O)ncn2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +CN1CCC(n2ncc3ccc(NC(=O)c4ccc(F)cc4)cc32)CC1 +O=C1N(c2ccc3scc(C(F)(F)F)c3c2)CCN1c1cnccc1C1CC1 +CC(C)C(NC(=O)C(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(N)=O +CNC(=O)c1cnc(N2CCN(c3nc4cc(C(F)(F)F)ccc4[nH]3)CC2)c(Cl)c1 +CCCNC(c1cc([N+](=O)[O-])cc2nc(O)c(O)nc12)P(=O)(O)O +NC1CCS(=O)(=O)c2sc(S(N)(=O)=O)cc21 +Cc1cnc(NCC(F)(F)c2ccc(F)cc2)c(=O)n1CC(=O)NCc1cnc(N)cn1 +Fc1cccc(Nc2ccnc3cc(-c4cnn(C5CCNCC5)c4)ccc23)c1 +CCC(=O)NCCc1nc(-c2nc(C)cs2)c(-c2ccc3ncsc3c2)[nH]1 +COc1ccc2oc(Cc3c(Cl)cccc3Cl)c(CCNC(C)=O)c2c1 +CCn1nccc1Oc1cc(CC2CCC(C)(O)CC2)cnc1NC(=O)NC +O=C(Cc1ccc2ncccc2c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc4ncccc4c3)s2)s1 +COCCOc1cc(C=CC(=O)NS(=O)(=O)CCC(C)C)n(Cc2ccc(C(F)(F)F)cc2Cl)n1 +CNc1nc(Nc2cc3c(cc2Cl)c(C(=O)N2CC4CC2CO4)cn3C)ncc1C(F)(F)F +O=C(O)Cc1ccc(CNc2cccc(-c3c(C(=O)c4ccccc4)cnc4ccccc34)c2)cc1 +O=C(O)c1cc(-c2cc3ccccc3s2)nc2c1cnn2Cc1ccncc1 +COC(=O)c1ccc(NCc2cncn2Cc2ccc(Br)cc2)cc1-c1ccccc1 +CC(C)N1CCN(CCN2CCN(C3CC(c4ccc(F)cc4)c4cc(Br)ccc43)CC2)C1=O +CCc1ccc(CN2CCC(NC(=O)CNC(=O)c3cccc(C(F)(F)F)c3)C2)cc1 +CCCCOC(=O)Nc1ccc(S(=O)(=O)n2cc(-c3cccs3)[nH]c2=O)cc1C +O=C(O)c1ccc(-c2ccc3c(c2)CC(NCC(O)c2ccc(Cl)cc2)CC3)cc1 +CC1CCC(C(=O)Nc2cc(Oc3ccc(C(=N)N)cc3)cc(Oc3ccc(C(=N)N)cc3)c2)CC1 +Cc1cn(-c2ccc3n(c2=O)CCN(C2CCC2Oc2cccc(C(F)(F)F)c2)C3=O)cn1 +CC(C)n1cc(C2=NCC(=O)N3CCc4c(I)cccc4C3=C2)cn1 +CCCNC(=O)CCCc1nc(-c2nc(C)cs2)c(-c2ccc3c(c2)OCO3)[nH]1 +COc1ccc2c(n1)CCN(C(=O)c1cc3ncc(Br)cn3n1)CC2 +Oc1nc(O)c(-c2ccc(-c3c(C=Cc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cc2)o1 +COc1cc(-c2ccc3cc(OC)ccc3c2)cc(-c2ccc3cc(OC)ccc3c2)c1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(Nc4ccc(N5CCC(N(C)C)C5)nc4)c3c2)cc(Cl)c1O +COC(=O)N(CC(=O)O)C(=O)c1c(F)ccc2c(C(F)(F)F)c(OC)ccc12 +Cc1cc(Nc2ncc(C#N)c(Nc3ccccc3C(N)=O)n2)ccc1N1CCN(C)CC1 +C=C1C(O)C2(O)OCC34C(CC5C(C)=CC(=O)C(O)C5(C)C23)OC(=O)CC14 +CCN1CCN(C(=Nc2cccc(F)c2)c2ccc(C(=O)N(CC)CC)cc2)CC1 +O=C(NCc1cccnc1Cl)c1cncc(-c2ccc(OC(F)(F)F)cc2)n1 +COc1cnc2c(NCc3nnc4ccc(-c5ccc(=O)n(C)c5)nn34)ccnc2c1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc(C4CCNCC4)cc3)nc12 +O=C1NCc2[nH]c3c(ccc4cnc(-c5cccc(OCCN6CCOCC6)c5)cc43)c21 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCNc3ncc4ccccc4n3)c2)c1 +CCOc1ccccc1-c1nnc(SCCCN2CCN(c3ccccc3OC)CC2)s1 +CN(CCO)CCNc1ccc(NCCN(C)CCO)c2c1C(=O)c1c(O)ccc(O)c1C2=O +CCc1c(C2CCN(Cc3ccccc3)CC2)n[nH]c1-c1ccc(Cl)cc1 +CC1=C(CO)C(=O)OC(C(C)C2CCC3C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC23C)C1 +COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(C(O)c3ccco3)CC12C +O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(F)c3)c3nc4ccccc4[nH]3)cc2F)S(=O)(=O)N1 +CN(C)CCCNc1cc(-c2ccc3ccccc3c2)nc2ccccc12 +CCCCC(C(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O +CCCCCCCCCCCCCCCCS(=O)(=O)Nc1c(OC)cc(OC)cc1OC +Cc1ccc(NC(=O)c2ccnc3[nH]c(-c4ccc(F)cc4)nc23)cn1 +NC(=O)c1nnc(NC2CCCCC2N)nc1Nc1cccc2c1ccn2C(F)F +Nc1ccc(-c2nc3ccc(-c4nc5ccccc5s4)cc3s2)cc1I +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1nc2ccccc2n1-c1cc(NCCO)ncn1 +O=C(Nc1ccc(F)cc1F)c1c(NCc2ccccc2)[nH]c(=O)n(O)c1=O +COc1ccc(C=C2SC(c3ccc(Cl)cc3)=NC2=O)c2ccccc12 +CN1CCC(n2cc(S(=O)(=O)c3ccc(F)cc3)c3cccnc32)C1 +Nc1cnc(Sc2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)cn1 +CCc1nn(C2CCCC2)c2c1CCn1c-2nnc1C1(C)CCCCC1 +CC(C)(C)OC(=O)NC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1 +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3cc(Cc4ccccc4)no3)CC2)C(c2ccccc2)C1 +CCOc1ccc(F)c(C2CC2NC(=O)Nc2cc(Cl)cnn2)c1Cl +CCCCCN1C(=O)C(=CNC23CC4CC(CC(C4)C2)C3)C(=O)c2cc(OC)cc(C)c21 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cc(-c4cccnc4)cc(-c4cccnc4)c3)o2)c1 +O=C(O)CCCOc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 +CC(C)C(NS(=O)(=O)c1ccc2oc3cc(NS(=O)(=O)c4ccccc4)ccc3c2c1)C(=O)O +O=C(NCc1ccnnc1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CC(C)CN(CCc1ccccc1)S(=O)(=O)c1ccc(N2CCN(S(C)(=O)=O)CC2)cc1F +COc1ccc2cc(S(=O)(=O)NC(CCCN=C(N)N)C(=O)N3CCC(C)CC3)cc(OC)c2c1 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+C=CC1(C)CC(=O)C2(O)C(C)(O1)C(O)C(OC(=O)NCCc1ccc(N)cc1)C1C(C)(C)CCC(O)C12C +CCOC(=O)c1nc(-c2ccc(NC(=O)Nc3ccc(N4CCOCC4=O)cc3)cc2F)nc(N2CCOCC2)c1OCC +Cc1ccc(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N(C)CCN(C)C)nc12 +O=C(NCCc1c[nH]cn1)c1ccc(-c2ccccc2)cc1 +CC(c1ccc(F)cc1)N(Cc1cccc(C(=O)O)c1)C(=O)c1cc2cc[nH]c2cn1 +Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOCC5)cc4n3Cc3ccccn3)cn12 +CC=CCN1CCC(N2CCN(c3ccccc3)CC2)C(O)C1 +COc1cccc2nc(C)n(-c3ccc(OCCCN4CCCC4)cc3)c(=O)c12 +CCC(=O)Nc1nc(C)c(-c2csc(Nc3cccc(C(C)=O)c3)n2)s1 +CCc1nn(Cc2ccc(-c3nc4ccccc4[nH]3)cc2)c(CC)c1CC(=O)O +O=C(Nc1nnc(-c2ccc3c(c2)CCCC3)o1)c1ccccc1 +COc1cc2nc(N3CCOCC3)nc(NC3CCN(C)CC3)c2cc1OC +O=C(NC(Cc1ccc(O)cc1)C(=O)O)c1cnn2c(C3CCCCC3)c(-c3ccc(F)cc3)cnc12 +CC1(N)CCC(Nc2c(C(N)=O)cnn3cc(-c4cncc(C(=O)O)c4)cc23)C1(C)C +Cc1cnc2[nH]cc(Cc3ccc(NCc4ccc(C(F)(F)F)nc4)nc3F)c2c1 +Cc1cc(CN2CCc3ccccc3C2C(=O)Nc2ccc(Cl)cc2Cl)ccc1OCC(=O)O +CC(NC1CC(CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1)C1OC(n2cnc3c(N)ncnc32)C(O)C1O 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+Cc1nn(-c2ccc3onc(N)c3c2)c2c(=O)n(-c3ccc(-c4ccccc4CN4CCC(O)C4)cc3)c(C)nc12 +CCOC(=O)N=S(C)(=O)Cc1cccc(Nc2ncc(F)c(-c3cccc4c3OCCC4)n2)c1 +Cc1ccc(-c2cc(NCC(C)O)c3ccccc3n2)cc1Cl +Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)nc1 +COc1ccc2c(C)c(C(=O)c3cc(OC)c(OC)c(OC)c3)oc2c1 +CCN(CC)c1ccc(NC(=O)C2CCc3cccc(OC)c3C2)cc1 +COc1cccc(-n2ncc3c(NN=Cc4ccncc4)ncnc32)c1 +CC1CCC(C(C)n2c(N3CCOCC3C)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CCN1C(=Cc2sc3ccc(OC)cc3[n+]2CC)C=Cc2ccccc21 +CC(=O)c1cn(CC(=O)N2CC(F)CC2C(=O)NCc2cccc(Cl)c2F)c2cc(OC(F)(F)F)ccc12 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(-c2ccncc2)cc1 +COc1ccc2ncnc(Nc3ccc(OC4CCN(C(=O)Nc5c(F)cccc5F)CC4)c(C)c3)c2c1 +CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccccc1CC(=O)O +CCOc1ccc(N(C(=O)OCC2CCC(COCC(=O)O)CC2)c2cccc(F)c2)cc1 +Cc1ccc2oc(=O)c3cnn(CC(=O)NC4CCN(Cc5ccccc5)CC4)c3c2c1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCN(C(=O)C3CCCCC3)CC2)c1 +CCCN(C)C(=O)c1ccc2c(c1)nc(Cc1ccc(OCC)cc1)n2CC1CC1 +CC(C)C(NC(=O)OCc1ccccc1Cl)C(=O)NC(CC(=O)O)C(=O)CF +O=C(C(O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(N2CCCC2)CC1 +NC(CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1Cc2conc2C1 +COc1ccc(N=C2c3cccc(Cl)c3C(=O)c3c(Cl)cccc32)cc1 +CC1(c2ccc(C=CC(=O)O)cc2)c2ccc(O)cc2CCN1c1ccc(CC(F)(F)F)cc1 +CN=C1CCc2c1n(C)c1ccc(OC(=O)NC)c(Cl)c21 +NC(=O)c1ccc2[nH]cc(CCCCN3CCN(c4ccc(O)cc4)CC3)c2c1 +Cc1c(Cc2ccccc2)nc(SCOCc2ccccc2)[nH]c1=O +CC(=O)Nc1ccc2c(Nc3cccc(Br)c3)ncnc2c1 +O=C(Nc1ccc(-c2nc3ccccc3s2)cc1)C1CCN(S(=O)(=O)c2cccs2)CC1 +O=C1Nc2ccccc2C1(c1c[nH]c2ccc(Br)cc12)c1c[nH]c2ccc(Br)cc12 +CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccccc2)cc1 +Cc1cc(SC2=C(O)OC(CCc3ccco3)(C(C)C)CC2=O)c(C(C)(C)C)cc1CO +CCCCc1ccc(-c2ccc(S(=O)(=O)NCCc3c[nH]c4ccccc34)cc2)cc1 +c1ccc(-c2nc(Nc3ccc4[nH]ncc4c3)c3cc(OCCN4CCOCC4)ccc3n2)cc1 +CN(C(=O)C(C)(C)C1(O)CCN(CCc2ccccc2Cl)CC1)C1CCCCC1 +O=C(CCCCCCC(=O)Nc1ccc2c(c1)C(=Cc1ccc[nH]1)C(=O)N2)NO +O=C(c1ccc(Cl)cc1Cl)N1CCCC(C(F)(F)F)C1 +COc1ccc(CN2CCN(CCCN3C(=O)c4ccccc4C3=O)CC2)cc1 +CC(=O)N1CCN2CC(C)C(C)(c3cccc(O)c3)CC2C1 +COC1CCC2(CC1)Cc1ccc(OC(F)(F)C(F)F)cc1C21N=C(N)N(C)C1=O +CC1=C2NCC3C(CCC4(C)C(C(=O)NC(c5ccccc5)c5ccccc5)CCC34)C2(C)CCC1=O +CCCN1CCC=C(c2ccc(Nc3nc(Nc4ccccc4C(N)=O)c4cc[nH]c4n3)c(F)c2)C1 +COc1ccc(C2CC(=O)N(Cc3cc(I)cc(C4(C(F)(F)F)N=N4)c3)C2)cc1OC1CCCC1 +CCNC(=O)Nc1nc2ccc(-c3ccccc3OCC)cc2s1 +CCC(=O)NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1 +CCOC(=O)c1cccc(-c2cnc(C(=O)CCc3ccc(-c4ccccc4)cc3)o2)n1 +COc1cccc(-c2cc3nc(NCCN)c4ncc(C)n4c3s2)c1 +COc1ccc(Nc2c3ccccc3nc3c(OCCCCN(CCCl)CCCl)cccc23)cc1N +CNC(=O)c1cnc(N)c2cc(-c3ccc(C(C)(C)C#N)cc3)sc12 +NS(=O)(=O)c1no[n+]([O-])c1-c1ccccc1 +COc1ccccc1N1CCN(CCN2C(=O)c3cc(I)ccc3C2c2ccccc2)CC1 +COc1c(C(=O)O)cc2c(c1CCn1cnc3c1NC=NCC3O)CCCC2 +CCC(CC)C(=O)Nc1cc(-c2ccc(OC)cc2)nc(-c2ccc(OC)cc2)n1 +CCCCC(O)C1CC(Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(C(C)=O)c1 +Cc1ncnc(C)c1C(=O)N1CC2CN(CCC(NC(=O)CC3CCCC3)c3cccc(F)c3)CC2C1 +CCC(=O)c1ccc(OCC(=O)N2CCN(CC(=O)Nc3ccc(C)cc3)CC2)cc1 +CCCCn1c(CC)c(C)cc(C(=O)NC2(C(=O)O)CCCCC2)c1=O +O=C(O)CC(NC(=O)CCC(=O)Nc1ccc2c(c1)CNC2)c1ccc2c(c1)OCO2 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2F)nc1-c1ccccc1Cl +CN1CCN2CC(c3ccc(Cl)cc3)c3ccccc3C2C1 +CNc1ccc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)cc1S(C)(=O)=O +CCC(C)Oc1ccc(CCCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 +CS(=O)(=O)c1cccc(-c2cccc3nc(Nc4ccc(CN5CCOCC5)cc4)nn23)c1 +CN(C)c1nc(N2CCC(COCCN3CCCC3)CC2)nc2scc(-c3ccccc3)c12 +O=C(Nc1ccccc1OCC(O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCCC1 +COc1ccc2c(OCC(O)CO)nc(C#N)c(-c3ccccc3)c2c1 +COc1c(C)cccc1Cc1cc2c(cc1Cl)COC21OC(CO)C(O)C(O)C1O +CC(C)(C)NCC(O)COc1ccc(-c2nc(C(F)(F)F)c[nH]2)cc1 +CCC(CO)NC(=O)Nc1cc2[nH]nc(-c3ccnc(C)c3)c2cn1 +CC1CC2OC2CC(O)C=CC(=O)Cc2cc(O)cc(O)c2C(=O)O1 +CC(C)c1cc2c(c(O)c1O)C1(C(=O)O)CCCC(C)(C)C1CC2 +CCC(C(=O)O)N1C(=O)C(=Cc2ccc(-c3cc(Cl)ccc3Cl)o2)SC1=S +O=C(O)c1ccc2c(c1)C(SCCNS(=O)(=O)c1ccc(C(F)(F)F)cc1)c1ccccc1CO2 +CN1CCc2ccc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4cccc(C#N)c4)c3)cc2C1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2N2N=C(c3ccccc3)NS2=O)cc1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCc1ccc2ccccc2n1 +O=C(CCN1CCCC1)Nc1ccc2nc3n(c(=O)c2c1)CCc1c-3[nH]c2ccccc12 +CCC(CC)n1cc2c3c(nc(C)nc31)N(c1ccc(C#N)cc1Cl)CC2 +COc1nn(Cc2cccc(Oc3ccccc3)c2)c(=O)o1 +COc1cc(C2CCNCC2)ccc1Nc1nc(Cc2cccc(F)c2F)n2cnnc2c1C(N)=O +Cc1noc(C)c1NS(=O)(=O)c1ccc(-c2cccc(C3CCNCC3)c2)cc1 +CCCCN(CC)c1nc(C)nc2c1nnn2-c1ccc(SC)cc1Br +COC(=O)c1ccc(Nc2nc(N(C)C)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2c(F)cccc2F)s1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCN(c2cncnc2)CC1 +CCCS(=O)(=O)N1CC=C(c2ccc3c(c2)CC(C2CCN(c4ncc(C5CC5)cn4)CC2)O3)CC1 +CC(C)CCc1ccc2c(NCCCNCc3ccco3)ccnc2c1 +O=C(O)C1CC2CC(Oc3cc(Cc4ccccc4)ccc3-c3nnn[nH]3)CCC2CN1 +N#Cc1ccc(Nc2nccc(OCc3cc(F)ccc3Br)n2)cc1 +Cc1cccc(-c2nc(C3CN(Cc4ccc(-c5nc6nc(C7CC7)nn6cc5-c5ccccc5)cc4)C3)n[nH]2)n1 +CC1(C2CCCC2)Cc2cc(OCc3ccc(C(=O)O)cc3)c(Cl)c(Cl)c2C1=O +CCCn1c(=O)[nH]c2[nH]c(C3CCCC3)nc2c1=O +Clc1ccc(-c2cc(N(CCCN3CCCCCC3)Cc3ccc4c(c3)OCO4)on2)cc1 +O=C(O)Cc1ccc(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c(OCC(F)(F)F)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1nc(-c2cccc(F)c2)no1 +CC(C)=CCCC(C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC45CC35CCC12C +Cc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4cn3)CC2)c1 +COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(-c2ncccn2)nc1OCCO +NC(=O)C(NC(CP(=O)(O)O)NC(=O)C(Cc1ccc(O)cc1)NC(CP(=O)(O)O)NCc1ccccc1)C(N)=O +CN1C(=O)N(c2ccc(C#Cc3cccc(F)c3)nn2)C2CCCC21 +COc1cc(-c2cnn(C)c2)c(C)cc1Nc1ncc2ccnc(-c3cnn(C)c3)c2n1 +CCC(=O)OC1(C(=O)CO)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C +Cc1cc(C)cc(Cn2c(=O)cc(N)n(Cc3ccccn3)c2=O)c1 +Cc1ccccc1C(=O)C#Cc1cn(COCCO)c(=O)[nH]c1=O +CC1CCN(C(=O)c2cccc(Nc3ccccc3Cl)n2)CC1 +O=c1cc(-c2ccc(Cl)cc2F)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1 +CN(C(=O)C(C#N)=Cc1cn(CC(=O)O)c2ccccc12)c1ccccc1 +O=C(Nc1cccc(Cl)c1)Nc1nc(CCNc2ncnc3ccsc23)cs1 +O=S1(=O)CCCN1C1CCN(C(c2ccc(Cl)cc2)c2cccnc2)CC1 +NS(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2ccccc2Br)c1O +O=C(CSc1ccccc1)NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CCN(CC)CCOc1cc(-c2nc(N)nc3sc(C(=O)NCC(F)(F)F)cc23)c(Cl)cc1Cl +Cc1ccc2c(c1)C(=NNC(=O)CCCN)c1ccccc1C2=O 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+O=P(O)(O)CNC(Cc1ccc2c(c1)Cc1ccccc1-2)c1nnn[nH]1 +CC(C)Cn1c2ccc(Nc3nccc(C(F)(F)F)n3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +CN=C1N(C)CC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCC(C)(C)CC3)c2)CN1C +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(NCC4CC4)c3Cl)C2)cc1 +CCc1c(Sc2cc(C)cc(C)c2)n(CCC2=CCCC2)c(=O)[nH]c1=O +COc1cccc(C(=O)N2CCn3c(-c4nc(C)ns4)nnc3C2C)c1 +CCC(C)C(=O)c1c[nH]c(C(Cc2ccccc2)CC(O)C(Cc2ccccc2)NC(=O)OC(C)(C)C)n1 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3cccc(OC)c3O)cc21 +COc1ncc(F)c(Nc2[nH]nc3c2CN(C(=O)OC(CN(C)C)c2ccccc2)C3(C)C)n1 +Cn1cc(NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)c(C(=O)N2CCC2)n1 +C#CCN(Cc1cc2c(O)nc(C)nc2cc1C)c1ccc(C(=O)NC(CCSc2nn[nH]n2)C(=O)O)c(F)c1 +COc1cccc(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1 +CC(O)(C#Cc1cc2c(cc1F)OCCn1c-2nc(C(N)=O)c1C1CC1)CO +Cc1nc2ccccc2n1Cc1nnc(Nc2ccc(Br)cc2)s1 +O=C(NCCNC(=O)c1ccc(-c2ccccc2)cc1)c1ccc(OC2C3CC4CC2CC(C(=O)O)(C4)C3)cc1 +COc1ccc2c(c1)CCC1N=C(NCC3CCC(CNS(=O)(=O)c4ccccc4)CC3)CC21 +Cc1cc([N+](=O)[O-])cc(C)c1NC1=NCCN1 +COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2Cl)cc1 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+COc1ccccc1N1CCN(CCCCNC(=O)c2sccc2C)CC1 +O=C(CSc1nc2ccc(N3C(=O)c4ccccc4C3=O)cc2s1)Nc1cccc(Cl)c1 +CNC1CCN(C(=O)c2cc3cccc(F)c3[nH]2)C1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3cccc(Cl)c3)c(C(=O)c3ccc(Cl)cc3)s2)cc1 +COc1ccc(C(=O)Nc2ccc(-c3ccc(OC4CCN(C)CC4)cc3)cc2)cc1-c1ccc(Cl)cc1 +COc1ccc(-c2c(C(=O)NC3CCN(Cc4ccncc4)CC3)noc2-c2cc(Cl)c(O)cc2O)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)c2nnn(Cc3ccccc3Br)c2C)CC1 +CN1Cc2ccc(NC(=O)NC3CC(CF)(CF)Oc4c3ccc(Cl)c4F)cc2NC1=O +Cc1ncccc1Oc1ncc(C#N)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +Cn1cc(-c2cc(C(=O)NCC(C)(C)O)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +C=Cc1nn(Cc2cc3cccc(C)c3c(=O)n2-c2ccccc2)c2ncnc(N)c12 +CCCCC(NC(=O)C1Cc2ccccc2CN1S(=O)(=O)c1ccc(OC)c(OC)c1)C(=O)O +CC(C)Nc1ccc(-c2ccccc2)c(CC(=O)NCc2ccc(C(=N)N)cc2)c1F +O=C(c1ccc(Oc2ccc(Cl)cc2O)c(Cl)c1)N1CCOCC1 +O=C(c1ccc(N2CCN(C(=O)c3ccccc3O)CC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +O=C(c1ccccn1)C1CC(Oc2ncccc2C2CCOCC2)C1 +Cc1cccc2cc(Cn3nc(C=C4SC(=O)NC4=O)c4c(N)ncnc43)n(-c3ccccc3F)c(=O)c12 +CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc2c(C(F)(F)F)noc12 +CCOc1ccc(-n2c(C)c3c(C)nnc(-c4ccc(Cl)cc4)c3c2C)cc1 +C=C(C)C(=O)N(CCCCN=c1c2ccccc2nc2n1CCCCCC2)CCCN=c1c2ccccc2nc2n1CCCCCC2 +NC1=NC(CCc2ccc(Nc3nccc(C(F)(F)F)n3)cc2)CO1 +Nc1ccc(-c2ccc3ncc4ncc(=O)n(C5CCN(C=O)CC5)c4c3c2)cn1 +Cc1ccc2oc(=O)n(C(=O)NCCCCc3ccccc3)c2c1 +CCCc1c(OCCCCOc2ccc(C=CC(=O)O)cc2)ccc2c(-c3ccccc3)noc12 +CCOC(O)=C1C(COCCN2CC(=O)NC2=O)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +COc1ccc(C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O +COc1ccc(CNCCCCc2cn(-c3ccc(F)cc3)c3ccccc23)cc1OC +Fc1ccc2nnc(-c3ccc4cccc(OC5CCNCC5F)c4n3)n2c1 +CCCN(CCC)C(=O)Cn1c2nc3ccccc3c(C)c2c(=O)n1-c1ccc(F)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(NCC4CCCCO4)c3Cl)C2)cc1 +Cn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2-c2ccc(C(F)(F)F)cc2)CC1 +Cn1nc(N2CCCC2)nc1CCc1nc2cc(C(F)(F)F)ccn2n1 +NC(=O)c1nn(CC(=O)N2C(C(=O)NCC3CC3(Cl)Cl)CC3CC32)c2cc(F)c(F)cc12 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1Nc1cnn(-c2ncc(F)cn2)c1 +C[S+]([O-])c1ccc(-n2cnc(-c3ccc(F)cc3)c2-c2ccncc2)cc1 +Cc1cn(CCCn2c(=S)[nH]c3ccccc3c2=O)cn1 +Cc1ccccc1CN(CCN(Cc1cncn1C)c1ccc(-c2ccccc2)cc1)S(=O)(=O)c1cn(C)cn1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)cc31)CN1CCC2CC1 +CC(Nc1ncnc(N)c1C#Cc1cccc(CO)n1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +O=C(NO)C1(S(=O)(=O)c2ccc(OCCCc3nc(-c4ccc(OC(F)(F)F)cc4)no3)cc2)CCOCC1 +CC(C)C(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1 +c1ccc2c(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)[nH]nc2c1 +COc1cccc2c1CCc1cc(Nc3ccc(F)cc3F)ccc1C2=O +CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(C(=O)O)cc3)cc(Oc3ccc(F)cc3F)c2)CC1 +CCCC(=O)c1cnc2c(OCCCN(C)CCCc3ccccc3)cccc2c1Nc1ccccc1C +CCN(CC)C(=O)c1nc(C2CCCCN2C(=O)COc2ccccc2)no1 +CCNC(=NC#N)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +O=C1c2ccccc2C(=O)N1CCOC(=S)N(C(=O)c1ccc(Cl)nc1)c1ccc(Cl)cc1 +COC(=O)CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(C)C(C)C)c2)[nH]1 +CC(C(=O)Nc1ccc(C(=O)O)cc1)n1cc(OC(F)F)c(-c2cc(Cl)ccc2C#N)cc1=O +CCCCCCN(C(=O)c1cc2cc(O)ccc2n1C)c1ccccc1 +CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 +O=C(c1ccc(Nc2nc3ccccc3n3nnnc23)cc1)N1CCNCC1 +COc1ccc(OC)c(S(=O)(=O)NC2CCC(N3CCN(c4ccccc4OC(C)C)CC3)CC2)c1 +NC(=O)CCNC(=O)C1C(C(=O)NCc2ccc(Br)cc2)C2C=CC1C21CC1 +O=S(=O)(c1cccc(F)c1)c1ccc2c3c(oc2c1)C1(CCOCC1)NCC3 +COc1cc(Cl)ncc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +O=C1CCc2cc(C=CC(=O)N3CCC(O)(c4ccccc4)CC3)cnc2N1 +CC(=O)n1ccc2cc(-n3c(O)nnc3-c3cc(C(C)C)c(O)cc3O)ccc21 +Cc1nc(Nc2ccccc2)c2[nH]c(-c3ccccc3)cc2n1 +CC1CCC2C(C)C(OCCN(C)Cc3no[n+]([O-])c3C#N)OC3OC4(C)CCC1C32OO4 +Cc1cc(NC(=O)C2(F)CCNCC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 +COc1ccc(NC2=C(N3CCCCC3)C(=O)c3ccccc3C2=O)cc1 +C#CCN1CCc2nc3nc(N4CCCCC4)c(C#N)cc3c(N)c2C1 +Cc1ccc(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)cc1 +Cc1nc2c(s1)C(c1cc(Cl)ccc1OCC(=O)O)N(C(=O)C1CC1c1ccccc1)CC2 +CC1(c2ccc(OCCN3CCCC3)cc2)c2ccc(O)cc2CCN1c1ccccc1 +CC(C)(C(=O)NC1C2CC3CC1CC(C(N)=O)(C3)C2)c1ccc(C#N)cn1 +COC(=O)NCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 +CC(C)(C)OC(=O)NCCCCCCCNC1CCN(CCc2ccccc2)CC1 +CCc1cn(-c2nc(NC)c3ncn(C4OC(CO)C(O)C4O)c3n2)nn1 +CN(C)C(=O)c1cc(CN(CCC#N)c2cc(F)cc(F)c2)c2oc(N3CCOCC3)cc(=O)c2c1 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+COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cn1ccc2ccc(C(=O)NCC3CCCC3)cc21 +Cc1c(C)c(CCO)c(C)c(C(CCCCCC(=O)O)c2ccc(F)cc2)c1O +CC=Cc1sc(-c2nccs2)nc1C(=O)NCCCNC(=O)CS +O=S(=O)(NCCCCN1CCc2ccccc2C1)c1ccccc1 +O=C(Nc1ncc(CCNc2ncnc3ccsc23)s1)Nc1ccccc1Cl +O=C(CCCn1cnc([N+](=O)[O-])n1)Nc1ccc(F)c(Cl)c1 +CC(C)(C)N1CCC(Oc2cc(-c3ccc(F)cc3F)c3ccc(=O)n(-c4c(F)cccc4F)c3c2)CC1 +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)n1cc(-c2cnn3ccc(Cl)nc23)cn1 +COc1ccc(C(=O)Nc2ccc(OCCCN(C)C)cc2)cc1Nc1nccc(-c2cccnc2)n1 +O=C(CCN1CCC(N2CCCC2)CC1)N1CCc2c(nc(O)c3ccccc23)C1 +COc1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 +COc1ccc(Nc2nc3cc([N+](=O)[O-])cc([N+](=O)[O-])c3nc2-c2ccccc2)cc1 +CC(c1ccccc1)c1nnc(-c2sc3ccccc3c2OC2CCNCC2)o1 +CC(C)c1ccc(S(=O)(=O)n2cc(CN3CCN(C)CC3)c3c(Cl)cccc32)cc1 +O=C(c1ccc2nc[nH]c2c1)N1CCCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1 +CN1CCCC(COC(=O)C(C)(c2ccccc2)c2ccccc2)C1 +Cc1ncnc(N2CCN(C)CC2)c1C#Cc1ccc(N)nc1 +CCn1c(C)nc(Cl)c1-c1noc(C2CCCCN2C(=O)COc2ccccc2)n1 +NS(=O)(=O)c1ccc(CNC(=O)Cc2cccs2)cc1 +CCCCc1nnc(SC(C)(C)C)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1cc2c(cc1OC)-c1n[nH]c(-c3ccc(C(F)(F)F)nc3)c1C2 +CCOC(=O)CN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +O=C(N1CCN(C(c2ccccc2)c2ccccc2)CC1)n1nnc2ncccc21 +NC(=O)c1nc(N2CCCC(NC(=O)N3Cc4ccccc4C3)C2)sc1Nc1ccccn1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1nnccc1C(=O)O +CC(C)CC(=O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CN)CC1 +CNC(=O)c1cccc(Nc2nccc(Oc3ccc4c(C(=O)Nc5ccccc5)cccc4c3)n2)c1 +Oc1ccc(-c2[nH]c3ccccc3c2C=NNc2ccccc2)cc1 +CC(=NOCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)c(F)c1 +O=c1cc(OCc2ccccc2)c2ccc3ccccc3c2[nH]1 +CN1Cc2ccc(NC(=O)NC3CC4(CCCC4)Oc4ccccc43)cc2NC1=O +NC(=O)C(Cc1ccccc1)NC(=O)CC(Cc1ccccc1)NC(=O)C1CCCN1C(=O)C(N)Cc1ccc(O)cc1 +CN1CCN(c2ccc(-c3ccc4[nH]c5nccc(C=Cc6ccccc6)c5c4c3)cn2)CC1 +CSC1=C(c2ccc(O)cc2)C(=O)c2cc(O)cc(O)c21 +N#Cc1cccc(S(=O)(=O)N2CCCc3ccc(Oc4cc(-c5nc(C6CC6)no5)cc(Cl)n4)cc32)c1 +COc1ccc(-c2cc(-c3ccc(S(C)(=O)=O)cc3)c(-c3ccncc3)c(=O)o2)cc1 +CNC(=O)COc1cccc(Nc2ncc(F)c(Nc3ccc(C)c(Cl)c3)n2)c1 +O=C(C1CCN(c2nnc(-n3cccc3)s2)CC1)N1CCN(c2cccc(C(F)(F)F)c2)CC1 +Cc1nc2cnc(Nc3ccnc(N4CCC(O)CC4)n3)cc2n1C(C)C +c1ccc2c(-c3cncc(-c4ccsc4)c3)c[nH]c2c1 +CC1=NC(C)=C(C(=O)O)C(c2ccoc2)C1=C(O)OCC=Cc1ccccc1 +Cc1nc(C(=O)O)c2c(n1)N(Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)CC2 +Cc1nc2c(NC3CCc4ccccc43)cc(-n3ccccc3=O)cn2c1C +O=C(c1ccc2nc[nH]c2c1)N1CCCC2c3ccccc3CCC21 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)C(F)(F)F +Cc1cccc(N2CCC(C(=O)Nc3ccc4c(c3)NC(=O)CO4)CC2)c1 +COc1cccc(-c2cc3nc(-c4ccccc4)c(C)c(N4CCN(C(=O)c5ccoc5)CC4)n3n2)c1 +CC1(c2cc(Br)cc(NC(=O)c3ccco3)c2)CCSC(N)=N1 +COc1cccc2c(S(=O)(=O)NC(CCCN=C(N)N)C(=O)N3CCC(C)CC3)cccc12 +Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1 +O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)C1CC(Cc2ccccc2)CN1C(=O)Cn1cncn1 +CC1(C)CC=C(c2cc(C3(O)CCS(=O)(=O)CC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +O=C(Nc1nc(-c2ccccc2)cs1)C1CCCN1C(=O)C(NC(=S)Nc1cccnc1)c1ccccc1 +CN(c1ccccc1)C1CCN(CCCOc2ccc(F)cc2)CC1 +O=S1(=O)NCc2ccccc2N1C1CCN(C2CCC3CCCCC3C2)CC1 +O=C(c1ccco1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21 +Cc1cccc(Cl)c1Nc1nc2cc(N(C)CCN3CCOCC3)ncc2n2cncc12 +COc1cc2nccc(Oc3ccc4c(C(=O)Nc5ccc(C(C)(C)C)cc5)cccc4c3)c2cc1OC +Cc1nc2cnc3cc(F)c(-c4ccc(Oc5nccc(F)n5)cc4Cl)cc3c2n1C1CCN(C(=O)CO)CC1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cc(C)cc(C)c2)c1 +CC(Nc1ncnc(N)c1C#Cc1ccc(F)cn1)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(C#N)c1 +Cc1cccc(S(=O)(=O)NCc2ccc(C(=O)NCCN(Cc3ccccc3)C(C)C)cc2)c1 +O=C(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1cc2ccccc2n1Cc1cccc(OCc2ccccc2)c1 +COc1cc(-c2cccc(C(F)(F)F)c2)c(C#N)cc1-c1nccc2cc(S(=O)(=O)Nc3ccon3)ccc12 +CCCc1nc2c(C)cc(C(=O)NC(COC)c3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCOc1cc(C=Cc2ccc(OC)c(O)c2)cc(OCC)c1OCC +Cc1c(C)c(O)c(C(CCCCCC(=O)O)c2ccc(F)cc2)c(C)c1O +COc1ccc(CN2CC3(CCN(CCc4c[nH]c5ccc(F)cc45)CC3)OC2=O)cc1 +CN(C)c1ccc(-c2nc3cc(OCCOCCOCCF)ccc3o2)cc1 +COc1cnc(C(=O)Nc2ccc(F)c(C3(C(F)F)COCC(N)=N3)c2)c(C)n1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NCc4ccccc4-n4ccnc4)nc23)N1 +CCC(CC)OC1C=C(C(=O)O)CC(NC(=N)NC(=O)CC(C)C)C1NC(C)=O +COc1ccccc1OC(=O)N1c2ccccc2Sc2ccccc21 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+COC1COCCC1NC1CCC(Cc2cccnc2)(C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)C1 +O=C(OC1CCOC1)N1CCC(CS(=O)(=O)N2CCC(c3ccccc3)CC2)(C(=O)NO)CC1 +CC(C)c1nc(C(=O)NC2CCN(CC(C)(C)O)CC2)c2ccccn12 +Cc1cc(Cc2ccc(Cl)c(Oc3cc(Cl)cc(C#N)c3)c2F)n[nH]c1=O +O=C(C1CC1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(O)cc(C(F)(F)F)c2)CC1 +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccc(Cl)c(F)c3)sc12 +CC1CC(Nc2nc(N3CCOCC3)[nH]c(=O)c2-c2ccc3ccccc3n2)C(O)C1O +c1ccc2c(OCC3CCCN3c3ccnc4ncnn34)cncc2c1 +O=C(c1cn(CC(F)(F)F)cn1)N1CCC(O)(c2ccccc2)C2CCCCC21 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(C#CC(C)(C)C)c2)c1 +C#CCN(Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)c1ccc2nc(N)nc(N)c2c1 +O=C1OC(CO)(COC(=O)C(c2ccccc2)c2ccccc2)CC1=Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 +CCc1ncnc(-c2ccc(C(=O)N3CCC(N(C)C)C3)c(C)c2)c1C#Cc1ccc(N)nc1 +COCCNC(=O)c1cccc(Nc2ncc3cc(-c4ccncc4)ccc3n2)c1 +O=C(NCC1CCNCC1F)c1c(F)cccc1-c1cccc(Cl)c1 +Cc1c2ccccc2nc2c1c(=O)n(-c1ccc(F)cc1)n2CC(=O)N(C)c1ccc(Cl)cc1 +CSCCC(NC(=O)c1ccc(COCc2ccc(-c3ccc(F)cc3)o2)cc1-c1ccccc1C)C(=O)O 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+CCCCOc1cc2c(cc1C(=C1CC1)c1ccc(C(=O)O)cn1)C(C)(C)CCC2(C)C +CCc1ccccc1Nc1nccc(-c2c[nH]c3ncccc23)n1 +O=C(NC1CCN(C(=O)c2ccccn2)CC1)NC12CC3CC(CC(C3)C1)C2 +Cc1ccccc1C(C(=O)NC1CCCCC1)N(C(=O)CNc1ccccc1)c1cccc(F)c1 +OC1CC2(n3cnc4c(NCc5ccccc5OCCF)nc(Cl)nc43)CC2C1O +COc1cccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)n1 +O=C(O)c1ccnc2cc(C(OCC3CCC(F)(F)CC3)c3ccccc3Cl)[nH]c12 +FC(F)(F)c1cccc(-c2ccc3nnc(CCl)n3n2)c1 +CCNc1n[nH]c2cc(NC(=O)NC3COc4ccccc4C3)ncc12 +Cn1nc(S(N)(=O)=O)sc1=NSC(=S)N1CCOCC1 +CC(C)(C)C(=O)CN(CCNc1ccnc2cc(Cl)ccc12)C(=O)c1cnccn1 +COCC(C)Oc1nc(C2CCCO2)c(C(=O)NC2C3CC4CC2CC(O)(C4)C3)s1 +O=C(c1ccc(C2=NCCN2)cc1)N1CCN(S(=O)(=O)c2ccc3cc(Br)ccc3c2)CC1 +Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccncc3N(C)C2=O)c1 +c1ccc2c(NCCCNc3c4c(nc5ccccc35)CCCC4)c3c(nc2c1)CCCC3 +NC1=NC2(CCOC1)c1cc(-c3cccnc3F)ccc1Oc1cnc(C3CCC(F)(F)C3)cc12 +CC1CC2(Cc3ccc(C#N)cc3C23N=C(N)N(CCc2ccncc2)C3=O)CC(C)C1O +CCCCN(C)C(=O)Cn1c2nc3ccccc3c(C)c2c(=O)n1-c1ccc(Cl)cc1 +CC(=NNc1ncnc2sc3c(c12)CCCC3)c1ccc2ccccc2n1 +COc1ccc(C(=O)NC(CNCc2ccc(C(=O)Nc3ccccc3N)cc2)Cc2c[nH]c3ccccc23)cc1 +Cc1ccc(Nc2c(Cl)cc(Cl)cc2Cl)c(CC(=O)O)c1 +NC(CNc1nc(-c2ccncc2)nc2c(C3CC3)csc12)Cc1ccccc1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCn1ncnn1 +COc1ccccc1C(=O)NCC1(c2ccc(Cl)cc2)CCOCC1 +COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3F)c2cc1OC +Cc1nnc2ccc(-c3cccc(C(F)(F)F)c3)nn12 +CN(C)CCc1cc(-c2ccncc2)c(-c2ccc(F)cc2)[nH]1 +CNC(=O)C(Cc1ccc2ccccc2c1)N1CCC(=O)N(Cc2ccc(O)c(OC)c2)C(CC(C)C)C1=O +C=Cc1ccc2c(c1)C(=O)N1CCCC1c1c(C(=O)OC(C)(C)C)ncn1-2 +N=C(N)c1cccc(-c2cc(-c3cc(C(=N)N)ccn3)no2)c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(S(N)(=O)=O)CC4)cc3OC)ncc2C(F)(F)F)c1 +CC(Nc1cc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)c1cccc(F)c1 +COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1 +O=C1NC(=O)c2ccc(I)cc2C1=CNCc1ccc(-c2cccnc2)c(O)c1 +CC1CN(S(=O)(=O)CC2CCC(N(C)c3ncnc4[nH]ccc34)CC2)CCN1C +Cc1nc(-c2cn3c(n2)-c2ccc(N4CCCC4CN4CCCC4)cc2OCC3)n(C(C)C)n1 +O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)c1cccnc1 +Cc1ncc([N+](=O)[O-])n1CCOC(c1ccccc1)c1ccccc1Cl +CC(C)(C)CC1NC(C(=O)NC2CCC(O)CC2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(F)ccc12 +O=[N+]([O-])c1ccccc1S(=O)(=O)NCC1CCC(CNCc2ccc3ccccc3n2)CC1 +O=C(NCC1CCOCC1)c1cnc(Nc2ccc(Cl)cc2Cl)cc1C1CCCC1 +COc1ccc(CNc2ncnc3c(CCO)c(OC)c(N(C)C(=O)C(C)C)cc23)cc1Cl +CC(=O)NC1=NN(C(C)=O)C(c2ccc(Br)cc2)S1 +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(OCCN)ccc3N2)c(O)c2cccnc21 +C=CCC(O)(CC=C)c1ccc(OCCCN2CCCCC2)cc1 +CN(C)c1ccc2c(c1)C(C#CC1CC1)(C(F)(F)F)OC(=O)N2 +COc1cc(C(C)=O)ccc1SCCCN1CCC(c2noc3cc(F)ccc23)CC1 +COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(C)cc4)cc3)c2cc1OC +CC1OC(=O)C2CC3COCCC3C(C=Cc3ccc(-c4cccc(C(F)(F)F)c4)cn3)C12 +Cc1c(S(=O)(=O)Nc2ccc(C(=O)NCC(=O)O)cc2S(C)(=O)=O)sc2ccc(F)cc12 +CNc1ncnc2c1ncn2C1OC(COP(=O)(O)O)CC1OP(=O)(O)O +CC(C)n1c2ccc(C(=O)c3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +Cc1cc(Cl)ccc1C1c2c(nn(-c3cccc(C#N)c3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F +COC(=O)c1ccc(F)cc1CS(=O)(=O)Nc1ccc(C)n(CC(=O)NC(CCCN=C(N)N)C(=O)O)c1=O +Cc1cccc(C)c1-c1noc(C)c1NC(=O)NCc1ccc(OC(C)C)nc1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1cc(Cl)c(Cl)cc1F +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NC1CC(F)(F)C1 +COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccccc2)cc1 +CCCN(C(=O)c1ccccc1)C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1 +CN(C)Cc1cc(CC(N)=O)ccc1Oc1ccc(Cl)c(Cl)c1 +Cc1cnnc(N2CCN(C(=O)Nc3ccc(C(C)(C)C)cc3)CC2)c1 +CC(CO)OCC(Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(C#N)cn1 +COc1ccc(Cn2c(CC(C)(C)C(=O)O)c3c4c(c(OCc5ccc(-c6ccccc6)cn5)ccc42)CC(C)S3)cc1 +FC(F)(F)c1ccc(Nc2nc(N3C4CCC3CC4)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccsc3)n(CC(=O)N3CCC(N4CCCC4)CC3)c2c1 +CSc1ccc(Cn2c(CC(C)(C)CC(=O)O)nc3cc(Cl)cnc32)cc1 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccn2cncc2c1 +COc1cccc2c1Cc1c(Nc3ccc4c(c3)OCCO4)n[nH]c1-2 +COc1c(OCC(O)CN2CCC2)ccc2c1N=C(NC(=O)c1cccnc1C)N1CCN=C21 +CN(C)Cc1ccc2c(c1)CN(C(=O)Nc1ccc(-c3n[nH]c(=O)c4ccccc34)cc1)C2 +O=C(O)CCc1ccc(OCc2ccc(CN3CCC4(CC3)CC(Cc3ccccc3F)CCO4)cc2)cc1 +O=C(NC1CCN(Cc2ccccc2)C1)c1cccc(-c2ccccc2)c1 +CCCn1ccc(=O)c2c(N)nc(-c3ccccc3)cc21 +CC(Nc1ncnc2ccc(OCCCCCCC(=O)NO)cc12)c1ccccc1 +COC1(c2ccccc2)CCCN(S(=O)(=O)c2ccc(C(C)(C)C)cc2)CC1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1NC(c1ccccc1)CC2c1ccccc1 +Cn1nc(-c2ccc(C(N)=O)cc2)sc1=NC1CCC(O)CC1 +CCc1ccnc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC4CCCN4CC2C)C3(C)C)c1 +Cc1ccoc1C(=O)Nc1ccc(F)c(-c2nc3ncccc3o2)c1 +Cc1cncc(C(=O)Nc2cccc(CN3CCC(C)(C(=O)NC4CCCCC4)CC3)c2)c1 +COc1ccc(C(=O)ON=C(N)Cc2ccc(Cl)cc2)c(OC)c1 +O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1c2c2cccc3c2n1CCC3CO +Cc1csc(NC(=O)c2cc(Sc3nccn3C)c(F)cc2N)n1 +CNCC(O)C(c1cccc(OC)c1)n1ccc2ccccc21 +O=[N+]([O-])c1cn2c(n1)OCC(OCc1cccnc1-c1ccc(OC(F)(F)F)cc1)C2 +O=[N+]([O-])c1ccc(CCNCC(O)COc2cccc3[nH]ccc23)cc1 +COc1cccc(CCCCCCc2cccc(OC)[n+]2C)[n+]1C +O=C(c1nn(-c2ccc(CN3CCOCC3)cc2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +O=C(CC1Sc2ccccc2N(CC(=O)N2CCCC2)C1=O)NO +C=C(CC)C(=O)c1ccc(OCC(=O)OCCc2ccc(O)cc2)c(Cl)c1Cl +Cc1cc(-c2ccccc2)cc(C)[n+]1CCc1ccc(S(N)(=O)=O)cc1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(NCc4ccccn4)n3)cccc2s1 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+CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccc(OC)cc2)[nH]c2ccccc12 +CCNC(=S)NNC(=O)CSc1nc2sc(C(=O)OCC)c(C)c2c(=O)n1CC +O=C(O)CCCC1(c2ccccc2)CCCN(C(=O)Nc2ccc(Cl)cc2)C1 +CCOC(=O)C1=C(C)Nc2nc3c(c(N)c2C1c1ccc([N+](=O)[O-])cc1)CCCC3 +N#Cc1cccc(Cn2cc(NC(=O)c3n[nH]c4cc(-c5cn[nH]c5)ccc34)cn2)c1 +CCCCc1ccc(-c2nnc(-c3ccccc3C(F)(F)F)n2C)c(C)c1 +COc1ccc2c(c1)CCCC2CCCCN1CCCC(C)(C)C1 +Cc1ccc(CN2CCN(CC(=O)C(O)(c3ccccc3)C3CCC3)CC2)cc1 +Brc1ccc2c3c(cccc13)-c1nc3ccccc3nc1-2 +CC(C)CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C +CC(Nc1ncnc(N)c1C#N)c1nn2ccc(C(F)(F)F)c2c(=O)n1-c1ccccc1 +CN(C)C(=O)CN(C)C(=O)Cn1c(-c2ccc(Cl)cc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CN(Cc1ccccc1)Cc1c[nH]c(-c2cccc(F)c2)n1 +COc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Sc2ccccc2C)CC1 +Cc1ccc(F)cc1C1NC(=O)C=C(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12 +Cn1cc(-c2ccc3nc(NC(=O)c4cccc(F)c4)cn3n2)c(-c2ccc(F)cc2)n1 +CCCn1c(=O)c2nc(C3C(C)(C)CCC3(C)C)[nH]c2n(CCC)c1=O +Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c1 +Cc1ccc(C2CC3CCC(C2c2ccc(C)cc2)N3C)cc1 +Cn1cc(-c2ccc3c(c2)CCC3=NO)c(-c2ccncc2)n1 +FC(F)(F)c1cnc(Nc2ccc(C3CNCCO3)c(Cl)c2)nc1 +O=C(O)c1ccc(Oc2ccc(CN3CCC(N4C(=O)N(C5CCOCC5)CC4c4cccc(Cl)c4)CC3)cn2)cc1 +CS(=O)(=O)c1ccc(-c2nc(-c3ccccc3)sc2-c2ccc(F)cc2)cc1 +Cn1cnc2cc(-c3ccc(N4CCNCC4)cc3)nc(NCCO)c2c1=O +Cn1c(-c2ccc3nccnc3c2)c(-c2ccoc2)c(=O)n1C +CN(C)CCCNC(=O)CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1 +Oc1cc(NCCCNCc2cccc(Cl)c2Cl)nc2ccccc12 +CC(C)Nc1nc(NC(=O)Nc2ccccc2)n2nc(-c3ccco3)nc2n1 +CC1(C)CC=C(c2cc(C3(O)CCOCC3)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +NCCNCCCCNCC1CCN(C(=O)Cc2cccc3ccccc23)CC1 +CCCCCc1cc(O)cc(OCCCCCCCCCCC(=O)NN2CCCCC2)c1 +CSc1ccc(Cc2ccc3c(c2)C2(OC3)OC(CO)C(O)C(O)C2O)cc1 +N=C(NOC(=O)c1ccc(Cl)cc1)c1[nH]ncc1Br +CS(=O)(=O)C(CCc1ccc(-c2ccccc2)cc1)C(=O)NO +N#Cc1ccccc1N1CCN(C(=O)COc2ccc3[nH]cc(CCN)c3c2)CC1 +CN1CCc2cc(O)ccc2Cc2[nH]c3ccccc3c2CC1 +CC(C)(C)C1CC(=Cc2ccccn2)C(=O)C(=Cc2ccccn2)C1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(Nc4ccc(CN(C)C)cn4)c3c2)cc(Cl)c1O +COc1cccc(CC2(c3ccc4[nH]ccc4c3)CCNC2)c1 +CC(=CCN1CCC(Cc2ccccc2)CC1)c1ccccc1 +Fc1ccn(Cc2c(F)ccc3c2CCC3c2ncc[nH]2)n1 +CN1CCC(N(C)C(=O)c2cc3cc(Nc4nccc(-c5cn(C)cn5)n4)cc(Cl)c3[nH]2)CC1 +CCOC(=O)c1cccc(NC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Br)c(C)nc34)c2Cl)c1 +COc1ccccc1N1CCN(CCCCc2cn(-c3ccc(SC)cc3)nn2)CC1 +O=C(Nc1cnn(S(=O)(=O)c2ccc(F)c(F)c2F)c1)c1ccccn1 +CCOC(=O)C1=CC2C(CC(OC(=O)C=Cc3cn(C)cn3)C3(C)C=CC1(OC)O3)C(C)=CCC2C(C)C +CCCn1c(=O)c2[nH]c(-c3cnn(-c4ccc[n+]([O-])c4)c3)nc2n(CC)c1=O +Cc1ncc(COP(=O)(O)O)c(C=NOCC(F)CN)c1O +O=C1COc2ccc(NC(=O)C3CCN(c4cccc(F)c4Br)CC3)cc2N1 +COC(=O)c1cnc(Oc2ccc3c(c2)B(O)OC3)cn1 +CC(CC(=O)Nc1cccc(Br)c1)=NNC(=O)c1ccc(O)cc1O +Cc1nc(NC(C)c2cccc(Br)c2)cc(-c2ccc3occ(C)c3c2)n1 +COCCOc1cc2c(N)nccc2cc1CC(C(=O)O)N1CCC(NS(=O)(=O)c2cnc(N(C)C)s2)C1=O +CC(=O)N1CCCN(c2ccc(OCc3cc4cnc(C#N)nc4n3CCC3CCCCC3)cc2)CC1 +CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(N)=O)cc3)c2)CC1 +CCOC12CCC(C(=O)C1)C1C(=O)N(CCCCN3CCN(c4ccccc4OC)CC3)C(=O)C12 +COc1cccc(-c2cc(COc3cccc(Cl)c3)cc3cccnc23)c1 +CCC(=O)NS(=O)(=O)c1ccc(OC)cc1-c1ccc(Cn2cncn2)cc1 +COc1cccc(Oc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +CC(C)(C)c1ccc(Cn2c(C(=O)O)cc3sccc32)cc1 +CCN1CCC(c2ccccc2)=C(C(=O)OCCc2ccc(F)cc2)C1 +CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3NC3CCCC3)cc2)cc1 +O=C(NC1CCCC1Nc1ccc(C(F)(F)F)cn1)c1c(F)cccc1F +COc1ccc(C=C2CSCC(=Cc3ccc(OC)c(O)c3)C2=O)cc1O +Cc1ccc2ccn(C3CCN(c4ccc(-c5cnn(C)c5)nn4)CC3)c2c1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1NC1CC1 +CCC(C)(C)C(=O)Nc1cc(CN2CCOCC2)c(N)cn1 +CNc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3Cl)c(=O)n(CC3OCC(NC)CO3)c2n1 +CN(Cc1cc2c3c(c1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn3CC(=O)N2C)CC(O)c1ccccc1 +CN1CCC23Cc4nc5ccc(C(F)(F)F)cc5cc4CC2(O)C1Cc1ccc(O)cc13 +COc1ccc(-c2cc3ncccc3c(OCC3CNC(=O)N3)n2)cc1OC +C=CC(=O)Nc1ccc(OC)c(Nc2cc(-c3[nH]c(SC)nc3C)ccn2)c1 +CN1CCN(c2cccc(-c3cnn4c(N)c(-c5ccc(NC(=O)CCC6CCCC6)cc5)cnc34)c2)CC1 +CN(Cc1cccc(-c2cnc(N3Cc4cccnc4C3)nc2)c1)C(=O)CN +COc1ccc(OCCCN(C)CCOc2ccc3c(c2)OCO3)c(C2(OC)Sc3ccccc3N(C)C2=O)c1 +COc1nc2cccnc2n1C1CCC(Nc2nc3ccccc3s2)CC1 +Cc1csc(-c2nc(C3CCC(=O)CC3)[nH]c2-c2ccc3ncsc3c2)n1 +c1ccc2c(c1)CCc1ccccc1N2CSCC1CCCN2CCCCC12 +CC(CCCCNS(=O)(=O)c1ccccc1)C1CCC2C(=CC=C3CC(O)CC(O)C3)CCCC21C +CCCCc1nnc(SCC(C)C)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)cc1 +CC1(C#Cc2ccc(C(=O)Nc3ccc(F)c(C4(C(F)F)N=C(N)OC5CC54)c3)nc2)COC1 +CCCCN1CCN(c2ccc(S(=O)(=O)Oc3ccc(OC)c(OC)c3)cc2)C1=O +CCOc1ccc(N2CC(Oc3ccc(C(C)NC(=O)c4cncs4)cc3)C2)cc1 +CSc1ccc(C=CC(=O)NC(=O)c2ccccc2O)cc1 +CCCCC(OC(Cc1ccccc1)C(=O)N1CCC(O)CC1)C(=O)NC(CC1CCCCC1)C(O)C(O)CC(C)C +Cc1cc(N)nc(C)c1CNC(=O)C1=CN(Cc2nc3ccccc3nc2C)NC1 +Cc1[nH]c(C#N)c(C)c1-c1ccnc(Nc2cccc(O)c2)n1 +Cc1cc2cc(CNc3ccc4c(c3)OCO4)c(=O)n(CCO)c2cc1C +CCNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC(C)C)ncc1C(F)(F)F +CC(CCc1ccc(O)cc1)NC(=O)Cc1c(-c2ccccc2)n(Cc2ccc(OCCCN3CCCCC3)cc2)c2ccccc12 +FC(F)(F)c1ccc(C(NCC2CCCCC2)c2cnccn2)cc1 +CC(C)(C#N)COc1ccc2c(c1)C1(COC(N)=N1)c1cc(-c3cncnc3)ccc1O2 +C=CCN1CCC23c4c5ccc(O)c4OC2C(=O)CCC3(OC)C1C5 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+N#Cc1cc(Cl)c(NC(=O)N2CCN3C(=O)N(C4CC4c4ccccc4)C(=O)C3C2)c(Cl)c1 +CCCS(=O)(=O)Nc1ccc(C)c(Nc2ccc3ncn(C)c(=O)c3c2)c1 +Nc1nc(-c2ncco2)nc2sc(Cc3ccccc3)cc12 +CC(=O)OC1CC2(C)C(CC(O)C3C4(C)CCC(O)C(C)C4CCC32C)C1=C(CCC=C(C)C)C(=O)O +C=C(C(=O)O)C1CCC(C)(O)C2CC(=O)C(C)=C2C1 +NC(C(=O)N1CCC(F)C1)C1CCC(NC(=O)OCc2ccccc2)CC1 +CCNC(=O)c1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccc3)c2c1 +Oc1cccc(C23CCCCC2CN(CCc2ccccc2)CC3)c1 +CCOC(=O)C1=C(C(CC)CC)c2ccc(OCCCc3ccccc3)cc2C1=[N+](C)[O-] +CNC(=O)C1OC(n2cnc3c(NCc4ccc(Br)cc4)ncnc32)C(O)C1O +Cc1cc(C)nc(N2CC3CN(C(=O)c4cnoc4-c4ccccc4)CC3C2)n1 +CCCN(CCC)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3)cc1 +CC(C)C(O)Cc1ccc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nn12 +Cc1ccc(NC(C)c2cc(C(=O)NCCN(C)C)cn3c(=O)cc(N4CCOCC4)nc23)cc1 +OCC1OC(SC2CCCC(n3cc(-c4ccsc4)nn3)C2O)C(O)C(n2cc(-c3ccsc3)nn2)C1O +CCc1cnc(C)nc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4ccc(C(F)(F)F)c(F)c4)o3)cc2Cl)CS1(=O)=O +COc1ccc2ccc(=O)oc2c1C1=NN(C(C)=O)C(c2ccc(C(F)(F)F)cc2)C1 +CC(C)Nc1nc(-c2ccc(C(C)NS(C)(=O)=O)cc2)cc2ncn(C)c(=O)c12 +NC1=NC(CF)(c2cc(NC(=O)c3ccc(Br)cn3)ccc2F)CC(C(F)(F)F)O1 +NC1=C(C=C2COc3ccccc3C2=O)C(=O)C2C=CC=CC2O1 +O=C(c1ccccc1)c1cc(Br)ccc1OCCn1ccc(=O)[nH]c1=O +COCC1OC(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C(O)C1O +Cn1cc(-c2cnc(N)c(C(=O)NCc3c(F)ccc(F)c3Cl)c2)cn1 +COc1ccc(C(=O)Nc2c(C)nn(COc3cccc(C(F)(F)F)c3)c2C)cc1 +COc1cc(CCNCCc2ccc(F)cc2)ccc1NC(=O)Nc1cnc(C#N)cn1 +Cc1ccc(Nc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)cn1 +CCC(O)C(C)C1OC1CC(C)(O)C=CC=C(C)C1OC(=O)CC(O)CCC(C)(O)C(OC(C)=O)CCC1C +N#CC1CN(C(=O)OCC(F)(F)CO)CCC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +CCCCNc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12 +CC1c2cc(O)ccc2CCN1Cc1ccccc1C(=O)NCCC=Cc1ccccc1 +O=C(COc1ccccc1)NC1C(=O)N2C(C(=O)O)=C(Cl)CSC12 +CC(Nc1cc(NCCc2ccccc2)ncn1)c1ccccc1 +Nc1nc(NCC2CCCN2Cc2cccnc2)nc2nc(-c3ccco3)nn12 +Cc1ccc2nsnc2c1S(=O)(=O)NCc1ccc2c(c1)OCO2 +COc1cc(OCc2csc(-c3ccc(C#N)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CC1CN(C2CC(c3ccc(F)cc3)c3ccc(Cl)cc32)CC(C)N1C +O=C(COc1ccccc1)N1CCCCC1c1nc(-c2ccc(=O)[nH]c2)no1 +O=C(O)CCc1ccc(-c2c(C3CC(c4ccc5ccccc5n4)C3)nc3c(N4CCOCC4)ccnn23)cc1 +O=C(Cc1ccccc1)NC1CCN(CCc2ccccc2)CC1 +CC1(C(=O)Nc2cc(C3CC3)n[nH]2)CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5cc6ccccc6s5)cc4s3)o2)CC1 +[C-]#[N+]C1=C(c2ccc(F)cc2F)N=C2COC(=O)C2C1c1ccc2n[nH]c(C)c2c1 +CN(C)CCn1cnnc1-c1cc(Oc2ccc(NC(=O)NN=Cc3cccc(Br)c3)cc2F)ccn1 +N#Cc1cnc2ccc(NCc3cc[nH]n3)cc2c1Nc1ccc(F)c(Cl)c1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccnc(N2CCCC2)c1 +CC1CN(Cc2ccc(-c3cccnc3C(=O)N3CCC(Nc4cccc(F)c4)CC3)cc2)CC(C)N1 +CNC(=O)Nc1nc2ccc(-c3cncc(S(=O)(=O)NC(C)(C)C)c3)cn2n1 +CS(=O)(=O)Cn1cnc2c(N3CCOCC3)nc(-c3cccc4[nH]ccc34)cc21 +Cn1c2c(c3cc(S(=O)(=O)c4cc(F)c5[nH]ccc5c4)ccc31)C1CCC(C2)N1 +N=C(N)c1ccc(OCCC2CCCCN2C(=O)C(CC2CCCCC2)NCC(=O)O)cc1 +Cc1onc(-c2cccc(F)c2)c1CNc1ccc(C(=O)NC(C)C)cn1 +CCCCCCN=c1ccn(Cc2ccc(OC)cc2)c2cc(Cl)ccc12 +Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccn2ccnc2c1 +COc1cccc(C2SC(c3ccc(F)cc3)=NN2C(=O)c2c(F)cc(F)cc2F)c1OC +CC1(O)CC(c2nc(-c3ccc4ccc(-c5ccccc5)nc4c3)c3c(N)ncnn23)C1 +CC(NC(=O)C1(C)CC(C)(Cl)C1)c1ccc2ccccc2c1 +Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccc(O)cc3)C2=O)cn1 +CNc1cc(-c2c(Nc3cc[nH]n3)nc3cccnn23)nc(C)n1 +COc1cncc(C2=CCC3C4CCC5=CC(=O)NCCC5(C)C4CCC23C)c1 +Cc1ccc(-c2cc(C3C(OC(c4ccc(F)cc4)c4ccc(F)cc4)CC4CCC3N4C)on2)cc1 +O=C(O)C1C2CN(C(=O)c3ccc(N4CC(F)(F)C4)c(OCC4CC4)n3)CC21 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1NC(=O)c1ccc2nc(NC(=O)Nc3cccnc3)sc2c1 +C(=Cc1cn2c(-c3ccc(N4CCNCC4)nc3)cnc(C3CCOCC3)c2n1)c1ccc2ccccc2n1 +CCc1cc2c(C3=NNC(=O)C3(C)C)ccc(CC)n2n1 +COc1cc(CN2CCC(C(=O)NC(C)(C)C)CC2)cc(NC(=O)c2ccc(F)cc2)c1 +O=C(Cc1ccc(F)cc1)Nc1nc2nn(CCCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCN(CC(=O)N(C)C)CC1 +CC(Oc1cc(C=C2SC(=S)N(CC(=O)O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 +O=C(c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1)N1CCN(c2cccc(Cl)c2)CC1 +CCCC(NC(=O)c1ccccn1)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 +COCC(=O)N1CCS(=O)(=Nc2cc(C)c3c(Nc4ccc(F)cc4OC(C)c4cc(C)no4)ncnc3c2)CC1 +CCOC(=O)C1=C(Nc2ccc3c(c2)CCCC3)SCC1=O +CCCC(C(N)=O)C(CC(C)C)C(=O)NC1CCCCN(Cc2cccc(-c3ccc(Cl)cc3Cl)c2)C1=O +CCc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(C)c(OC)c3)[nH]c(=O)c12 +Cc1ccc(-c2nc(C(=O)Nc3cccc(C(=O)O)c3)c(CCC34CC5CC(CC(C5)C3)C4)[nH]2)c(C)c1 +CCN(CC)c1ccc2cc(C(=O)NCCCCn3nc(C(=O)NC4CC5CCCC(C4)N5C)c4ccccc43)c(=O)oc2c1 +NC(=O)c1ccc(Nc2nccc(Nc3cccc(C(F)(F)F)c3)n2)cc1 +COc1cccc(C[n+]2ccc(C=C3OCc4c(ccc(OC)c4OC)C3=O)cc2)c1 +COC(=O)N1CCC(c2cccnc2OC2CC(Nc3nc4ccccc4s3)C2)CC1 +C=CCN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCC1 +COc1cccc(-c2cc(NC(C)c3cccc(Br)c3)nc(C)n2)c1Cl +O=C(NC12CC3CC(CC(C3)C1)C2)C1Cc2c(sc3ccccc23)CN1 +C#Cc1cccc(Nc2ncnc3ccc4nc(C(=N)OC)sc4c23)c1 +NCCCCn1c(SCCc2c[nH]c3ccccc23)nnc1-c1cnc2ccccc2n1 +Cc1cc(C#N)cc2nc(-c3ccc(NC(=O)COC4CCN(CC(=O)OC(C)(C)C)CC4)cc3)oc12 +CCC(C)n1ccnc1C=CC(=O)C=Cc1nccn1C(C)CC +CC(Oc1cc(-c2cn(C)nc2C(F)(F)F)cc2ncccc12)C1CNC(=O)C1 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12)N1CC(O)C1 +c1cc(NC2CCCCC2)nc(Nc2ccc3[nH]ncc3c2)n1 +COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(CSc1nnnn1-c1ccccc1)C2=O +CCCc1[nH]c(C2Cc3ccccc3N2C(=O)CN)nc1C(=O)OCC +CCNC(=O)C(C)NC(=O)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +CC(C)=CCN(Cc1ccccc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +Cc1nc(-c2c(F)cc(Cl)cc2-c2cc(F)c3c(c2)CCC3NC(=O)C2(NC(=O)OC(C)(C)C)CC2)no1 +Cc1cccc(-c2nc(CNc3ccc(S(N)(=O)=O)cc3)cn2-c2ccc3c(c2)OCO3)n1 +Cc1cnc(CNCC2(F)CCN(C(=O)c3ccc(F)c(Cl)c3)CC2)cn1 +CNC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1Nc1cccc(OC(C)C)c1 +CC(C)(C)c1cc(-c2nc3nc(-c4ccccc4C(F)(F)F)cc(Cl)c3[nH]2)on1 +O=C(Nc1n[nH]c2cc(C(=O)NC(CN3CCOCC3)c3ccccc3)sc12)c1ccc(N2CCOCC2)cc1 +Cc1c(Cl)cccc1-c1noc(C2CCN2C(=O)c2cc(C(F)(F)F)ccc2-n2nccn2)n1 +CC(C)Oc1nc(Nc2ccc(OC(F)(F)F)cc2)cc(Nc2nccn2-c2cccc(C(F)(F)F)c2)n1 +O=C(NCCN1CC2CC(n3c(=O)[nH]c4ccccc43)CC2C1)c1cc2cc(F)ccc2[nH]1 +Clc1ccc(Cl)c(CN2CCN(c3nc4ccncc4nc3NC3CC3)CC2)c1 +Cc1nc(NC(C)c2ccc(OC(F)(F)F)cc2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2c(C(C)C)nccc2s1 +CCNC(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)cc2)N=C(c2cccc(C)c2)N1 +CS(=O)(=O)N1CCC(O)(c2cncnc2Nc2ccc(F)cc2)CC1 +CC(=O)N1CCN(C(=O)c2cc(Cl)cc(CSc3cnc(NC(=O)c4ccc(N(C)C)cc4)s3)c2)CC1 +CC1CNC(=O)c2cc(-c3ccnc(N)n3)[nH]c21 +Oc1ccc2c(c1)CC1(C2)C(c2ccccc2)=Cc2ccccc21 +COc1ccc(NC(=O)Nc2ccc(-c3ccc(C(=O)C4CCCC4C(=O)O)cc3)cc2F)cc1 +Cc1ccc(-c2ncccn2)c(C(=O)N2CCCOC2Cn2cc(-c3ccc(F)cc3)cn2)c1 +CC1(C)Cc2nc(N3CCOc4ccc(-c5cnn(CCN)c5)cc43)sc2C(=O)N1 +Cc1ccc(C#CC(C=CCOc2ccc(OCC(=O)O)c(C)c2)c2ccc(Br)cc2)s1 +Cc1nc(-c2ccccn2)nc(NCC(NC(=O)CCN2CCN(CCO)CC2)c2ccccc2)c1Cl +NC(Cn1c(=O)c(-c2ccccc2F)cn(Cc2c(F)cccc2C(F)(F)F)c1=O)c1ccccc1 +COC1CCC2(CC1)Cc1ccc(OCC3CCC3)cc1C21N=C(N)N(CC(F)(F)F)C1=O +N#Cc1cccc(Cn2cc(NC(=O)c3n[nH]c4cc(-c5ccncc5)ccc34)cn2)c1 +CCCCCc1[nH]c2ccc3c(c2c1C(=O)OCC)CN1CCc2cc(OC)ccc2C1O3 +CCOC(=O)CCc1cccc(-c2cc(C)cc(Nc3nccc(C4CC4)n3)c2)c1 +N#Cc1c(N)nc(N)nc1NC(c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cccnc1)C1CC1 +CC1c2ncn(-c3ccccn3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1F +Cc1ccc2c(n1)C(=O)C1=C(C2=O)S(=O)(=O)C=CN1 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+Cn1ncnc1COc1nn2c(-c3cccs3)nncc2c1-c1ccccc1 +N=c1c2ccccc2c(-c2ccccc2)nn1Cc1cc(O)ns1 +Cc1cn(-c2ccc3n(c2=O)CCN(CCOc2ccccc2C2CCC2)C3=O)cn1 +CCNc1nc(-c2ccc(S(=O)(=O)CCN(C)C)cc2)cc2ncn(C)c(=O)c12 +CC(=O)N(C)C1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 +CC(C)(C)c1ccc2c(c1)CCC2NC(=S)Nc1cccc2[nH]ncc12 +Cc1cc(OCc2ccccc2)cc(C)c1C=CC1CC(O)CC(=O)O1 +COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)[nH]c3ccc(Cl)cc23)CC1 +COc1ccc2c(c1)C(=O)N(c1nc(C(=O)Nc3cc(F)ccc3N3CCNCC3)cs1)C2 +O=C(O)C(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C1OCOC1C(=O)Nc1nc2ccccc2s1 +C=C(Br)C(=O)Nc1cccc(C=CC(=O)Nc2cccc(F)c2)c1 +CCN1CCN(Cc2ccc(NC(=O)c3cccc(-c4ccc5nc(Nc6ccccn6)sc5n4)c3)cc2C(F)(F)F)CC1 +N=C(N)NCC(=O)NCC1(Nc2ccc(Cl)c(Cl)c2)CCN(Cc2ccccc2)CC1 +CCCCCCN(CCCCCC)C(=O)Cc1coc(-c2ccc(C)cc2)n1 +O=C1CCCN1CCCNc1nc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2o1 +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(Cl)c3)cn2CCN2CCCC2)CC1 +Cc1cc(COc2ccc(S(=O)(=O)CC3(CC(=O)NO)CCCN(C)C3)cc2)c2ccccc2n1 +Cc1cccc(-c2nc(NCc3cccc(F)c3)sc2-c2ccc3ncnn3c2)n1 +COc1cnc(OC)n2nc(NS(=O)(=O)c3c(Cl)cccc3Cl)nc12 +C(=C(c1ccccc1)N1CCN(CCCCc2ccccc2)CC1)c1ccccc1 +N#Cc1ccc(Cn2cncc2CN2CCCN(C(=O)c3cccc4ccccc34)CC2)cc1 +COCCc1ccc(OC)cc1Nc1nc2ccccc2nc1NS(=O)(=O)c1cn(C)cn1 +Cc1cc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)ccc2N2CC(N)C(O)C2)[nH]n1 +OCC1CC(Nc2nc(Nc3cccnc3)ncc2-c2nc3cnccc3s2)C(O)C1O +O=C(NCCCc1ccccc1)c1ccc(NC(=O)N2Cc3cncnc3C2)cc1 +COc1cccc(-c2nc3ccccc3c(C(=O)NC(C)c3ccccc3)c2CN2CCC(N3CCCCC3)CC2)c1 +NC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(-c4c(F)cccc4Cl)c3)CC3CC32)c2cnccc12 +CC1NCc2cncn2Cc2ccc(C#N)c(c2)Oc2ccc3cccc(c3c2)N(C)C1=O +COC(=O)C(C)NP(=O)(OCC1C=CC(n2cc(C)c(=O)[nH]c2=O)O1)Oc1ccc(Cl)c(Cl)c1 +COc1cc(-c2c[nH]c(=O)c(-c3cc(OC)c(OC)c(OC)c3)n2)ccc1O +Cn1c(N2CCN(c3ccccn3)CC2)nc2c1c(=O)n(Cc1ccc(Cl)cc1)c(=O)n2C +N#CCC(=O)N1CCCCC12CCN(c1ncnc3nc[nH]c13)C2 +CNC(=O)COc1ccc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c(C(=O)NC)c1 +Nc1ncnc2c1C(=O)N(c1ccc(C3CCC(Cc4nn[nH]n4)CC3)cc1)CCO2 +CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc32)cc(CCC)c1OC(C(=O)O)c1ccc(CC)cc1 +CCCN1CCc2cc(OCCO)cc3c2C1Cc1cccc(O)c1-3 +Cc1cc(=O)oc2cc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)ccc12 +COCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C#N +O=C(NS(=O)(=O)c1ccc(Cl)cc1)c1cc2ccccc2n1Cc1cccc(C(F)(F)F)c1 +Cc1cn(CCCn2c(=S)[nH]c3sc4c(c3c2=O)CCCCCC4)cn1 +CCC1(CCC(C)C)CN(C2CCCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O +O=C(C#Cc1ccccc1)N1CCN(c2ncccc2[N+](=O)[O-])CC1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCC(C(F)F)C3)n2)cc1OC(F)F +COc1cc(C(=O)NCc2c(F)cc(F)cc2F)ccc1-c1cn[nH]c1 +CC(=O)COc1ccc(C23c4ccccc4C(=O)N2CCN3C(=O)c2ccc(F)cc2)cc1 +CC(C)C(NC(=O)c1cc(C(=O)NCc2cnccn2)c2n1CCOC2)c1ccc(F)cc1 +C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +COc1ccc(Cc2nc3c(ncn3C(CCCc3ccccc3)C(C)=O)c(=O)[nH]2)cc1OC +CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCC(C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +COc1cc2c(Nc3ncc(CC(=O)Nc4ccccc4C(N)=O)s3)ncnc2cc1OCCCN1CCCC1CO +Cc1noc(C)c1-c1ccc2[nH]nc(-c3cc(N4CCOCC4)ncn3)c2c1 +CCCn1c(=O)c2[nH]c(-c3cc(OCC#Cc4cccc(F)c4)no3)nc2n(CCC)c1=O +Cc1cc(Nc2ncc(-c3nc4cnccc4s3)c(NC3CC(CO)C(O)C3O)n2)ccn1 +Oc1cc(O)cc(CNC2COC(C(c3ccccc3)c3ccccc3)CC2O)c1 +O=C(NCC(F)(F)F)Nc1cncc(-c2cnc3cc(Cl)ccn23)c1 +C=CCn1c(=O)c2c(-c3cc(C#N)cn3C)n(Cc3ccnc4ccc(Cl)cc34)nc2n(CC2CC2)c1=O +CCOC(=O)c1nnc(Nc2cccnc2Oc2ccccc2C(C)(C)C)s1 +CCOC(=O)c1c[nH]c2ccc(OCc3ccc(OC(F)(F)F)cc3)cc2c1=O +Cc1nc(C#Cc2ccc(-c3cccc(Cl)c3C)nc2)cs1 +CN(C)C=Nc1nc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(C#N)cc2)n1 +Cc1ccccc1C1=CCC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 +Cc1c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)ccn2cc(C#N)cc12 +Nc1ccccc1-c1ccc2c(c1)sc1c(N)ncnc12 +CCOP(=O)(c1ccc(N)cc1)N1Cc2ccccc2CC1C(=O)NO +O=C(c1cccc2c(CN3CCN(C4CCC4)CC3)c[nH]c12)N1CCCCC1 +N#Cc1c2c(c(O)c3ncc(Cc4cccc(Cl)c4F)cc13)C(=O)N1CCCC21 +COc1cccc(-n2cc(C(=O)N3CCN(c4ccc5ncccc5c4)CC3)nc2-c2ccc(C)cc2)c1 +CC1(C)OC(=O)C(Nc2ccccc2)=C1c1ccc(S(C)(=O)=O)cc1 +COc1cc2c(C(O)CCCN(C)C)cc3c4cc5c(cc4ncc3c2cc1OC)OCO5 +C=CCN1C2CCC1C1CCC2N1C(c1ccc(C(=O)N2CCCC2)cc1)c1cccc(O)c1 +CN(C(=O)Cc1cccc2sccc12)C1CCCCC1N1CCC(CO)C1 +Cc1ccc(C(CO)Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1 +COc1cc(C=C2CCCN3C2=NOCC3C(O)c2ccc(Cl)cc2)ccc1-n1cnc(C)c1 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)CNC(C)(C)CCCC(C)C)cc13)N(C)S(=O)(=O)C2 +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1CCN1CCOCC1 +CN(C)CCNC(C(=O)NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc(F)cc1 +COCC(=O)Nc1ccc2[nH]nc(-c3cc4ccc(C)cc4[nH]3)c2c1 +COc1ccc2c(c1N)CCC=C2c1cc(OC)c(OC)c(OC)c1 +CN(C)C1CCN(CCc2c(COc3ccc(Br)cc3C(N)=O)sc3ccccc23)CC1 +C[Si](C)(CN1CC(O)C(O)C(O)C1CO)c1ccccc1 +O=C1NC(=O)c2c1c1c3ccccc3n3c1c1c2c2ccccc2n1C1CCC3N1 +CC1CN(c2nc(N3CCOCC3)c3ccc(Nc4ccncc4)nc3n2)CC(C)O1 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC2(C)C1(O)C(=O)CSc1nc2ccccc2s1 +Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccsc2)s1 +CC(=O)Nc1cc(N2CCCC2CO)nc(-n2nc(C)cc2C)n1 +c1ccc(CNc2nccc(Nc3cc(C4CC4)[nH]n3)n2)cc1 +c1cc[n+](CCCCCCC[n+]2cccc3ccccc32)cc1 +CNC(=O)c1cnccc1Nc1nc(-c2cc(Cl)ccc2F)nc2ncccc12 +CC(=O)N1CCC(NC(=O)NC23CC4(F)CC(F)(CC(F)(C4)C2)C3)CC1 +CC(C)(C)OC(=O)N1CCC(COC2CCC(c3ccc(S(C)(=O)=O)cc3F)CC2)CC1 +Cn1nc2c(c1-c1ccccc1)-c1nc(Nc3ccn(CCN4CCN(CCO)CC4)n3)ncc1CC2 +CC(=O)Nc1nc(Cc2nnc(SCC(=O)NN=Cc3ccccc3)n2NC(=O)c2ccccc2)cs1 +CC(=O)N1CCC(n2cc(-c3coc4c(OC(C)c5c(Cl)ccc(F)c5Cl)c(N)ncc34)cn2)CC1 +O=C(CCCCCNc1c2c(nc3cc(Cl)cc(Cl)c13)CCCC2)NCCc1c[nH]c2ccccc12 +CCN(CC)C(=O)NC(C(=O)N1CCCC1C(=O)Nc1nc(-c2ccccc2)cs1)c1ccccc1 +CC1=C(N2CCC3(CCN(CC(O)c4ccc5c(c4F)COC5=O)CC3)C2=O)COC1=O +N#CC(Cc1ccc(-c2ccc(C(N)=O)cc2)cc1)NC(=O)C1NC2CCC1CC2 +CCC(CC)C(=O)Nc1cc(-c2ccccc2)nc(-c2ccccc2)n1 +ON=C1c2ccccc2-c2ccc(OCCN3CCCCC3)cc21 +Cc1noc(C)c1S(=O)(=O)N1CCCN(C(=O)c2cccc(Cc3nnc(O)c4ccccc34)c2)CC1 +Cc1ccc(OC(=O)N(CC(=O)O)Cc2cccc(OCc3nc(-c4ccccc4Cl)oc3C)c2)cc1 +COCCCOc1cc(C(=O)N(CC2CNCC2OCc2cccc3ccccc23)C(C)C)ccc1OC +N#Cc1ncc2cc(Cc3ccc(Cl)cc3)n(CCC3CCCCCCC3)c2n1 +COc1cccc2c1c(NS(=O)(=O)c1cccc(Cl)c1Cl)nn2C +O=C(CCCN1CCC(C(=O)c2ccc(F)cc2)CC1)c1ccc(F)cc1 +COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1OCCCN(C)CCO +CN1CC(NC(=O)Nc2cccc(-c3nnnn3C)c2)C(CN2CCCC(Cc3ccc(F)cc3)C2)OC1=O +O=C(c1nn(-c2ccc(CN3CCCCC3)nc2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CCc1ncnc(-c2cc(F)c(C(=O)N3CCN(C)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +[N-]=[N+]=Nc1ccc(CN2CCN(CCCN(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1I +COc1ccc(CCNCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)cc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCNC(=O)CCSSc4ccccn4)cc3)[nH]c2n(CCC)c1=O +O=C(NCC1(c2ccccc2)CCCCC1)C1CCOc2ncccc21 +Cc1cccc(NC(=S)n2cc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)n2)c1 +C=Cc1ccc2c(-c3ccnc(NC4CC4)n3)cnn2n1 +CC(NCCc1ccccc1)c1nc2c(C(N)=O)cccc2[nH]1 +N#CC1CCCN1C(=O)CNCCNc1ccc(C(F)(F)F)cn1 +Cc1c(Cl)cccc1S(=O)(=O)N1CCCC(C(=O)NC2CCCCC2)C1 +c1ccc2c(c1)CCC2CCCN1CCN(c2cccc3c2OCCO3)CC1 +O=C(Nc1ccccc1)C1=C(O)CCn2c1nc1ncccc12 +NS(=O)(=O)OCC1CC(Nc2ncnc3nc(-c4cccc5cccnc45)[nH]c23)CC1O +NS(=O)(=O)c1ccc(NC(S)=NC(Cc2c[nH]cn2)C(=O)NCC(=O)O)cc1 +Cc1cc(O)cc(C)c1CC(C(=O)N1Cc2ccccc2CC1C(=O)O)N(C)C +Cc1ccc2nc(NC(=O)CNC(=O)c3nn(-c4ccccc4)c(=O)c4ccccc34)sc2c1 +O=C(NCc1ccccc1)OC1COC2C(OC(=O)c3ccccc3O)COC12 +CC1(C)CC(=O)c2c(ccc3c2C(c2ccc(Cl)cc2)Oc2ccccc2-3)N1 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+COCCN1CC(C(=O)N2CC(C)C(O)(c3ccccc3)C(C)C2)C(c2ccc(F)cc2F)C1 +O=S(=O)(c1ccc(Cl)cc1)N1CC=C(c2ccc3[nH]cc(CCN4CCCC4)c3c2)CC1 +Cc1ncnc(-c2ccc(C(C)(C)C#N)cc2)c1C#Cc1ccc(N)nc1 +CCS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CCCN1CCN(C(=O)CO)CC1)CCCC3)C(=O)N2 +Cc1csc(Cc2c(C3CCC(c4ccccc4)CC3)[nH]c(=O)[nH]c2=O)n1 +CNCC(=O)NC(c1cccc(F)c1N1CCN(C(=O)C(C)Cc2ccc(Cl)cc2Cl)CC1)C(C)C +O=C(NCC1(c2ccc(Cl)cc2)CCOCC1)c1ccccc1Cl +OCCNc1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12 +CNc1nc(Nc2cnn3c2C(C)OCC3)ncc1C(F)(F)F +CN1CCOCC1c1nc(O)c(O)c(C(=O)NCc2ccc(F)cc2)n1 +CCCCCCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(CN2CCOCC2)c1 +CCNN(CC(=O)N1CSCC1C#N)C1CCN(CC(=O)Nc2ccc(Cl)cn2)CC1 +CCc1ccc2c(c1)[nH]c(=O)c1nc(-c3ccccc3Cl)[nH]c12 +Fc1ccc(C23CCN(CC2)Cc2cc(-c4ccc(C(F)(F)F)nn4)ccc23)cc1Cl +Cc1cnc(Nc2cnn(C)c2)nc1NC1CC2CN(c3ccc(C#N)cn3)CC2C1 +O=C(O)c1ccc2nc(Nc3cccc(Cl)c3)c3cccn3c2c1 +CN1C2CCC1C(C(=O)OCCc1ccc(N)cc1)C(OC(=O)c1ccccc1)C2 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCCc3cccs3)[nH]c3ccc(Cl)cc23)c1 +COCC(=O)n1nc(-c2ccc(C)cc2)nc1NCc1ccc(F)cc1 +CC(=O)CC1(O)c2ccc(Br)cc2-[n+]2ccc3c([nH]c4ccccc43)c21 +O=C(NC1CCCN(CC2CC2)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +COCCNc1cc(Nc2ncc(F)c(-c3cnc(N4CCCOCC4)c(C#N)c3)n2)ccn1 +CCNc1nc(C#Cc2ccc(Cl)s2)nc2c1ncn2C1C(O)C(O)C2(C(=O)NC)CC12 +Fc1ccc(C(OCCN2CCN(Cc3ccc4ncccc4c3)CC2)c2ccc(F)cc2)cc1 +Nc1nc(-c2ccc3c(N)n[nH]c3c2)cc(N2CCCC(NC(=O)c3ccccc3)C2)n1 +CN(C)CCCOc1ccc(-c2nc3ccccc3n2CC=CCn2c(-c3ccc(OCCCN(C)C)cc3)nc3ccccc32)cc1 +C=CCS(=O)(=O)c1ccc(Nc2ncc(C(F)(F)F)c(OC(C)C(C)(C)O)n2)cc1 +CCCCCCCC[n+]1ccc(C(=O)NCCCCCCNC(=O)c2cc[n+](CCCCCCCC)cc2)cc1 +CC1(C)CCN(c2cnc(C#Cc3ccccc3)cn2)C(=O)N1 +CCOC(=O)N1CCC(NCCNC(=O)c2ccccc2C)CC1 +CCN(CC)CCCNc1cc(Nc2cc(C(C)C)[nH]n2)nc(NCc2cc(C(C)C)no2)n1 +CCc1cc(-c2ccc(-n3c(C)cc(C=C4SC(=O)NC4=O)c3C)cc2)ccc1C=C1SC(=O)NC1=O +CCCSc1sc(-c2cc[nH]n2)c2c1C(=O)NCC2CC +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(C(=O)CC#N)CC2)CC1c1ccc(Cl)cc1 +CC(C(=O)NC(CCCCCC(=O)NO)C(=O)Nc1cccc2cccnc12)c1ccc(N2Cc3ccccc3C2=O)cc1 +N#Cc1ccc2[nH]cc(C3=CCC(N4CCCCC4)CC3)c2c1 +COCCOCCOCC(=O)N1CCC(c2nc(-c3ccc([S+](C)[O-])cc3)c(Sc3ccc(Cl)cn3)o2)CC1 +CC(C(=O)OC1C[N+]2(CCOc3ccncc3)CCC1CC2)(c1ccccc1)N1CCCCC1 +O=C(NCC1CCCNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 +CC1(O)CCC2C(CCC3C2CCC2(C)C(C(=O)Cn4ncnn4)CCC32)C1 +CCc1c(N)ncnc1N1CCC(c2nc(-c3cccc(C(F)(F)F)n3)cn2CCN2CCC2)CC1 +CC(Cc1ccc(-c2ccccc2)cc1)SC(=O)C(C)NC(=O)CCC(=O)c1ccccc1 +COc1ccc(-c2c(C(=O)O)c(C(N)=O)cc3ccc4c(c23)OCO4)cc1OC +Cc1csc2c(NC(C)CN3CCN(S(=O)(=O)c4cccc(Cl)c4)CC3)ncnc12 +CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2cc(Br)cc(Br)c2)CC1 +CCS(=O)(=O)N1CCN(Cc2ccccc2C2(O)CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)CC1 +Cc1oc2ccc(NC(=NC#N)NC3CCCCN(CC(=O)N4CCCC4)C3=O)cc2c1C +Clc1cc(NCCCN2CCOCC2)c2cc3c(nc2c1)c1ccccc1n3CCN1CCCC1 +Cc1nc(N)sc1CCCNC(=N)NC(=O)CC(C)c1ccccc1 +CCCCCCCCCCOC(=O)C1=C(c2ccccc2)CCN(CC)C1 +O=C(Cc1cc[n+]([O-])cc1)N1CCN(C2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c32)CC1 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cc(N)cc(C#N)c1 +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)NCc1cccc(F)c1 +CCOC(=O)c1cnc(SC)nc1NN1C(=O)C=C(C)C1=O +Cc1ncoc1-c1nnc(SCCCN2CC3CCN(c4ccccc4)C3C2)n1C +O=c1cc(N2CC3CC2CO3)nc2n1CCC(C(F)(F)F)N2CC1(O)CC1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CCC(C3)N4CC(=O)N(C)CCO)cc12 +c1ccc(-c2cc(CCCCN3CCN(c4ccccc4)CC3)on2)cc1 +COc1ccc2c(c(CCNC(C)=O)c(I)n2C)c1[N+](=O)[O-] +CCC(CC)C(=O)Nc1ccc(N2CCN(C(c3ccccc3)c3nc(C)no3)CC2)c(F)c1 +CCCCN1C(=O)C(=CNC2CCCCC2)C(=O)c2c(C)cccc21 +CONC(=S)NN=C1C(=O)N(CN2CCN(c3ccc(Cl)cc3)CC2)c2ccc(Cl)cc21 +N=C(N)NCCCC(NC(=O)C1c2ccccc2-c2ccccc21)C(=O)NCc1ccc(C(F)(F)F)cc1 +Cc1ccc2[nH]c(-c3ccc[nH]3)c(C3CC(=O)NC3=O)c2c1 +Cc1ccccc1N1CCN(CC(O)CN2CCC(c3ccccc3)(c3ccccc3)C2=O)CC1 +Cc1cccn2cc(-c3ccc(OCCCCN4CCN(c5cccc(Cl)c5Cl)CC4)cc3)nc12 +Cc1cc(C(C)(C)C)nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)n1 +Nc1nc(N)c2nc(CCc3cccc4ccccc34)cnc2n1 +COC(=O)c1ccc(Oc2cccc(C(=N)N)c2)c(NC(=O)c2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN2CCN=C2SC)c1Cl +O=C(Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1)C1CCC2(CC1)OOC1(OO2)C2CC3CC(C2)CC1C3 +OC1COC(C(c2ccccc2)c2ccccc2)CC1NCc1ccccc1 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+O=c1[nH]c(CCCN2CC=C(c3ccccc3)CC2)nc2cccc(Cl)c12 +CC(C)CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O +COc1cc2c(cc1OC)CN(CCCCn1cc(CCF)c3ccccc31)CC2 +c1ccc(C2=NCC(N3CCN(c4ccccc4)CC3)CCN2)cc1 +Cn1nccc1-c1cc(C(F)(F)F)cc2[nH]ncc12 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2(O)Cc1ccc2ccccc2c1 +Cc1ccccc1-n1c(Cn2nc(-c3ccc4nc(N)ccc4c3)c3c(N)ncnc32)cc2cccc(C)c2c1=O +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O +CCCc1nc2c(C)cc(C(=O)NCCCc3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCNc1n[nH]c2cc(NC(=O)NC3CNc4ccccc4C3)ncc12 +Cc1ccc(CN2CCC(Oc3cccc(C(=O)N(C)CCN(C)C)c3)CC2)cc1C +COc1cc(OC)cc(C(=O)NC2CCN(CC=Cc3ccccc3)C2)c1 +CC1CCCN1CCOc1ccc(C2Oc3ccc(O)cc3SC2c2ccc(O)cc2)cc1 +CCCCc1nnc(SCc2ccc(C(=O)O)cc2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(Cc4ncco4)c4ccccc43)CC2)C(C)C)c1 +O=C(O)C(CC#Cc1ccc(F)cc1F)NCP(=O)(O)O +CN(Cc1ccccc1)S(=O)(=O)Nc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 +O=S(=O)(c1ccccc1)c1c[nH]c2cccc(CCNC3CCCC3)c12 +CCOC(c1cccnc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +COCC(F)(F)CN1CCN(C(=O)c2cc3c(cc2C)[nH]c(=O)c2cnn(C4CCOC4)c23)CC1 +COc1cc(-c2ccc(C(F)(F)F)cc2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CCC(C)(C)n1nnnc1C(c1ccc(O)cc1)N1CCc2ccccc2C1 +CCN(CC)c1ccc(CN(CCc2ccccc2)S(=O)(=O)c2ccc(C)cc2)cc1 +CCCCCCCCCCC1(NC(=O)Nc2c(CC)cccc2CC)CCCC1 +CC(=O)N1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc21 +CCOC(=O)c1[nH]c(C#N)c(-c2ccc(OC)c(OC)c2OC)c1Br +NCc1ccc(CNc2nc(NCc3ccccc3Cl)ncc2[N+](=O)[O-])cc1 +CC(C)C(=O)N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +Cc1cccc2sc(-c3ccc(NC(=O)C4CCN(S(=O)(=O)c5cccs5)CC4)cc3)nc12 +NCCCCNC(=O)c1cccc(Nc2nccc(-c3cccnc3)n2)c1 +COc1cc2ncnc(N3CCOC(c4ccccc4Cl)C3)c2cc1OC +CN1C(=N)NC(C)(c2cc(NC(=S)c3ccc(C(F)(F)F)cn3)cc(F)c2F)CS1(=O)=O +COc1cccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC4CCCN4CC2Cc2ccccc2)C3(C)C)c1 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(S(=O)(=O)c3ccccc3)CC2)cc1 +CCCn1c(=O)c2c(nc(C=Cc3cccc([N+](=O)[O-])c3)n2C)n(CCC)c1=O +COc1cnccc1-c1cccnc1Oc1ccc(C(=O)c2nc3ccccc3[nH]2)cc1 +COc1cc2cc(C(=O)N3CC(CCl)c4ccc(N)cc43)[nH]c2cc1OCCN(C)C +CCCc1n[nH]c2c1C(c1ccc(OC)cc1)c1c(nc3c(c1N)CCCC3)O2 +O=C(O)c1ccc(C(=O)Nc2ccc3c(OCc4cccc(Cl)c4)cccc3c2)cc1 +COC(=O)c1cccc(-c2cnc(C(=O)CCc3ccc(-c4ccc(CN5CCSCC5)cc4)cc3)o2)n1 +CCOc1cccc(CN2CCCC(N3CCc4cc(OC)c(OC)cc4C3)C2)c1O +O=C(NCC(O)C(=O)O)c1ccc(CN(C(=O)Nc2ccc(SC(F)(F)F)cc2)c2ccc(C3CCCCC3)cc2)cc1 +O=C(NC1CNCC(F)(F)C1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 +CCN(Cc1cccnc1)C(=O)c1ccc(Cl)c(C2(C)C(=O)N(Cc3ccc(OC)cc3OC)c3ccc(Cl)cc32)c1 +O=C(CCCCCCc1nc(-c2cccc(Br)c2)cs1)NO +C=CCN1CC=C(C2=Cc3ccccc3Oc3ccccc32)CC1 +CC(NC(=O)C(F)F)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 +CC(C)c1nc2ccccc2c(=O)n1-c1ccc(OCCCN2CCCC2)cc1 +O=C(CSc1oc(-c2ccc(Cl)cc2)nc1[P+](c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1 +CC(C)c1nn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-c3cccnc3)c12 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2CC=C(C)C +Cc1cccc(NC(=O)CN2CCN(c3ccccc3C#N)CC2)c1 +CC(C)(C)C(=O)Nc1nc(-c2ccccc2)cc(-c2ccccc2)n1 +Cn1c(=O)c2ccccc2n(Cc2nc3ccccc3n2CCCCF)c1=O +COc1ccc(S(=O)(=O)N(Cc2ccc(N3CCN(C)CC3)cc2)c2c(C)cccc2C(=O)NO)cc1 +COc1cc(N)ccc1C(=O)NC(=O)NC1CC2CCC(C1)N2C +Nn1c(CCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2ccccc2c1=O +OB(O)c1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1 +CC(C)(NC(=O)c1ccc(N2CC(F)(F)C2)c(-c2cccc(Cl)c2)n1)c1nccs1 +O=C1Nc2ccccc2C1=Cc1cc[n+](Cc2ccccc2Br)cc1 +CCOc1c(CN2CC3(CC(N4CCC(C)(C(=O)O)CC4)=NO3)C2)cc(C2CC2)c(-c2ccc(F)cc2)c1C +CCCn1c2cc(OCc3ccccc3)ccc2c2cc[n+](Cc3ccccc3F)c(C)c21 +CCOC(=O)c1csc(C(Cc2ccc([N+](=O)[O-])cc2)NC(=O)c2cccc3ccccc23)n1 +COC(c1ccc(Cl)cc1)(c1ccc2c(c1)c(-c1ccccc1F)cc(=O)n2C)c1cncn1C +Cc1ccc(C2CN(C(=O)C3CCNCC3)CC2c2ccc(C#N)cc2)cc1 +O=C(NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1)C1CC1(F)F +CCCCCCCCCCCCCCCC(=O)OC1=CC2C(=O)C3(C=C(C)C(O)C3(O)C1O)C(C)CC1C2C1(C)CO +CCCc1nc(SC(F)F)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CC2CCCCC2)cc1 +CNC(=O)c1cc(-c2ccc(Cl)cc2Cl)c(CN)c(C)n1 +NCCC(=O)NCCOc1cc(-c2ccccc2Cl)c2ccc(=O)n(-c3c(Cl)cccc3Cl)c2c1 +COc1ccc(CC(=O)N2CCN(c3nc(Nc4cc(C)[nH]n4)c4cccn4n3)CC2)cc1 +FC(F)(F)c1cc(Cl)c(-n2cc3c(n2)CCC3(F)F)c(Cl)c1 +COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=S)s3)c2cc1OC +Nc1ccc(CC(C(=O)O)c2cn(CC3CCCN(C(=O)C(c4ccccc4)c4ccccc4)C3)cn2)cn1 +COC(=O)C(c1ccccc1)C1CCCCN1Cc1ccc(Cl)s1 +CCC(=O)N1c2ccccc2-c2nnc(SC)nc2OC1c1cc(OC)c(OC)c(OC)c1 +Nc1ncc(C(=O)NC2CC2)c2ccc(-c3cccc(F)c3)nc12 +Cc1ccn(CC(=O)C2CCC3C4CCC5CC(C)(O)CCC5C4CCC23C)n1 +C=CCNC(=O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O +O=C1OC(c2ccc([N+](=O)[O-])cc2)=NC1=Cc1cccnc1 +COc1cccc(C2(c3cc(OCc4ccc5ccccc5n4)ccc3-c3n[nH]c(=O)o3)CC3CCC2C3)c1 +COc1ccc(CN2C(=O)c3cccc(N4CCN(Cc5c(F)cccc5F)CC4)c3C2=O)cc1OC +COc1cccc2c1-c1ccc(NS(C)(=O)=O)cc1C(c1cccc(Oc3ccccc3)c1)O2 +CC(=Cc1sc2ccc3occc3c2[n+]1CCO)C=C1Sc2ccc3ccoc3c2N1CCO +CN1CCN(c2ccc(Nc3ncc4cc([N+](=O)[O-])c(=O)n(C5CCCC5)c4n3)cc2)CC1 +CSc1cccc(NC(=O)Nc2ccc(OS(N)(=O)=O)cc2)c1 +O=S(=O)(Nc1ncns1)c1cc(F)c(OCC2CN(CC(F)F)CCC2c2ccc(Cl)cc2)cc1F +Cc1ccc(CN(C)Cc2ccccc2)cc1NC(=O)c1ccc(Nc2ncc(C)c(C)n2)cc1 +CC1(COc2ccc(-c3ccc(F)cc3)nc2)Cn2cc([N+](=O)[O-])nc2O1 +Cn1nnc2ccc(C(c3ccc(OS(N)(=O)=O)cc3)n3cncn3)cc21 +CC(C(O)c1ccc2c(c1)CC(=O)N2)N1CCC(c2ccccc2)CC1 +CC(=O)N1CCC(N(C)C(=O)NC2CCC(c3cc(F)cc(F)c3)CC2)CC1 +Cc1ccc(NC(=O)CC2CC2)cc1-c1ccc(C(=O)NCC2CC2)cc1 +CCNC(=O)c1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)c(C)cc1C1CCC1 +Cc1cc(C)cc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(S(C)(=O)=O)cc2)c1 +CCc1cccc(CC)c1-c1cc(OC)c2c(n1)CCCC2N(C)c1cc(OC)ccc1Cl +CN(C)S(=O)(=O)c1ccc(Nc2cc(NC3CCC(N)CC3)nc3c(Br)cnn23)cc1Cl +CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1OC +CC1CCN(Cc2ccc3nc(NC(=O)NN=Cc4ccc(OCc5ccc(Cl)cc5)cc4O)sc3c2)CC1 +CNCCC(c1cccc(F)c1)N1C(=O)C2(CCCCC2)c2ccccc21 +O=C1Nc2ccc(C(=O)NC(CO)c3ccc(F)cc3)cc2C1=Cc1ccc[nH]1 +CC1(C)CCC(C)(C)c2cc3c(cc21)CCCc1c(-c2ccc(C(=O)O)cc2)cn(Cc2cccnc2)c1-3 +CC(C)N(C(=O)C1CCC2C3CCc4c(ccc(C(=O)O)c4Cl)C3CCC12C)C(C)C +O=C(O)CCN(C1(C(=O)NO)CCC1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1 +CC1CCCN(c2ncnc3[nH]cc(-c4cnc5cc[nH]c5c4)c23)C1 +CN(C)CCNc1n[n+]([O-])c2c3c(ccc2[n+]1[O-])OCCC3 +C=CCNc1nc(NCC=C)nc(N2CCC(NCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)n1 +[H]C([H])([H])N(c1ncc(-c2nc3ccc(O)cc3o2)cn1)C([H])([H])[H] +O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(-c3ncc(C(F)(F)F)[nH]3)c2)cc1Cl +NC(=O)c1ccc2[nH]c(-c3ccc(C(=O)C4CCCCC4)cc3)nc2c1 +c1ccc(CNc2ccc3c(c2)C24CCCCC2C(C3)N(CC2CC2)CC4)cc1 +COc1cccc(-c2cnc(N)nc2-c2c[nH]c3ccccc23)c1 +CN(C)C1CCN(c2ccc(NC(=O)CCCC(=O)c3ccccc3)cc2)C1 +O=c1cc2c(nn1Cc1ccc(C(F)(F)F)cc1)CCNCC2 +COc1ccc(CC(=O)N2CCN(c3ccc(C4=NNC(=O)CC4C)cc3)CC2)cc1 +COc1cc(-n2c(-c3cccc4cc[nH]c34)cccc2=O)cc(OC)c1OC +CC#Cc1cncc(-c2ccc3c(c2)C2(CO3)N=C(N)CC2C(F)(F)F)c1 +C#CCCCn1c(Sc2ccc(Br)cc2Cl)nc2c(N)ncnc21 +CCC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(C#CCCCC(=O)N3CCOCC3)c2c(=O)n1-c1ccccc1 +Cc1nnc(-c2ccc(-c3ccc(-c4nc5nc(OC6COC7C(O)COC67)[nH]c5cc4Cl)cc3)cc2)o1 +COc1c(NC(=O)C(=O)c2ccc(OCCCCN3CCOCC3)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O +CSc1ccc2ccn(C3OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C3O)c(=O)c2c1 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+Cc1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)ccc(F)c2F)cc1 +OC(c1cccnc1)(c1cccc(F)c1)c1ccccc1Cl +O=C(C1CCCN(c2ccc3nc(C4(n5cc(C(F)(F)F)cn5)CC4)[nH]c3n2)C1)N1CCCC1 +CN(CC=Cc1ccc(Cl)cc1)Cc1ccc2c(c1)CCCC2 +CC(NC(=O)Nc1cc2[nH]nc(-c3cnn(C)c3)c2cn1)c1ccccc1 +Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(-c3ccnc(N)n3)cc21 +Cc1cc(OCC(=O)O)cc(C)c1Cc1ccc(O)c(C(C)C)c1 +O=C(O)CN1C(=O)C(NC(=O)C(S)Cc2ccccc2)CSC1c1ccccc1 +Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccccn3)nn2)CC1 +CC(C)(C)c1ccc(NC(=O)c2ccccc2Cn2ccc3cnccc32)cc1 +Fc1cccc(C2CC2CNCCc2ccnc(-n3ccnc3)n2)c1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1Cl +CNC(=O)CCn1cc(-c2cnc(N)c3c(-c4ccc(Oc5ccccc5)cc4)csc23)cn1 +CC(c1ccccc1)c1ccc2c(n1)Nc1ccc(-n3cnc(Cl)c3)cc1NC2=O +CCn1ncc(CN2CCCC(C(=O)c3cccc(OC(C)C)c3)C2)c1C +c1ccc2c(c1)OCC(c1nc3ccc(-c4ccncc4)cc3[nH]1)O2 +Cc1n[nH]c2c(C)cc(C(=O)N3C4CCC3CC3(Cc5cn(C(C)(C)C)nc5C(=O)N3)C4)cc12 +Cn1c2ccnc(Cl)c2c2nc(CN3CCOCC3)nc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c21 +O=C1CC2(Cc3ccc(NC(=O)Cn4c(=O)n(-c5ccccn5)c5ccccc54)cc3C2)C(=O)N1 +NCCCOc1ccc(Cl)cc1C(=O)Nc1ccc2c(c1)S(=O)(=O)C=C2 +O=C1CC2(CCN(c3c(Cl)cncc3-c3ccc(N4CCOCC4)cc3)CC2)C(=O)N1 +O=C(NC1(c2ccccc2)CCCCC1)C1CCCC1c1cc(-c2ccccc2)on1 +Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(N3CCOCC3)ncn2)s1 +CC(C)(Cc1ccc2ccccc2c1)NCCCOc1cccc(Cl)c1C#N +CN1CCCC1C1C[S+]([O-])C(c2ccccc2)(C2CCCCC2)O1 +COc1cccc(C23CC2CN(CCCSc2nnc(-c4ocnc4C)n2C)C3)c1 +COc1ccc(C2=NNC(=O)C3CCCCC23)cc1OC1CCCC1 +CCOC(=O)C(Cc1ccccc1)Nc1nc2ccc(C(C)C)cc2o1 +Cc1nn(-c2ccnc(Nc3ccc4c(cnn4C)c3)n2)cc1CN1CC(O)C1 +CN1CCC(CNc2ccc(C(=O)Nc3n[nH]c4cc(OCCOCc5ccccc5)ccc34)cc2)CC1 +Cc1[nH]nc2c1C(c1cc(-c3ccc(Cl)s3)cc(C(F)(F)F)c1)(C(C)C)C(C#N)=C(N)O2 +Cc1cc(OCCCN2CCCC2=O)cc(C)c1-c1cccc(COc2ccc(CCC(=O)O)c(F)c2)c1 +CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)C(=O)N(c3ccc(C(F)(F)F)cc3)C2)cc1 +CSc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 +CCCNC(CCC(C)C)Cc1ccc(OC)c(OCCc2ccccc2)c1 +C=C(c1cc(C)cc(C)c1OCC(O)CNC(C)C)n1ccnc1 +COCCN(C)c1ccc(NC(=O)c2nc(-c3ccccc3)oc2C(F)(F)F)cc1 +COC(=O)C1C2CCC3CCC1N(CC2=Cc1ccc(-c2ccc(N(C)C)cc2)cc1)C3 +CNc1nc(Nc2ccc(C(=O)N3CCC(C(C)(C)O)CC3)cc2OC)ncc1Br +CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OCCCc1ccc(OC)c(OC)c1 +COc1ccc(Cn2c(CCc3ccccc3)nnc2C(NC(=O)c2ccccc2)c2c[nH]c3ccccc23)cc1 +CN=C(N)Nc1ccc(NC(=O)Nc2ccc(NC(N)=NC)cc2)cc1 +CN(C)CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(N)c1 +Cc1noc(C)c1-c1ccc2c(c1)C(c1ccccc1)(N1CCCC(O)C1)C(=O)N2 +O=C(NCc1ccccc1)OC1COC2C(OC(=O)c3cccnc3)COC12 +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCCCCNC(=O)C2CN(C)CCC2c2ccc(Cl)cc2)C1 +O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1ccccc1F +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)c3ccncc3)CC2)cc1 +COc1cc2cc(c1OCCN1CCCC1)COCC=CCOCc1cccc(c1)-c1ccnc(n1)N2 +COCc1nc2c(C(=O)Nc3nc4ccccc4o3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +Cn1ccnc1C1Nc2cccc3c(=O)[nH]nc(c23)C1c1ccccc1 +O=C(CN1CCCCC1)Nc1cc(COC(=O)CN2CCCCC2)cc(Nc2ccnc3cc(Cl)ccc23)c1 +Nc1noc2cccc(C(=O)Nc3cccc(CNC(=O)Nc4ccc(F)c(F)c4)c3)c12 +N=C(N)c1ccc2[nH]c(-c3cc(C(CC(=O)O)C(=O)O)cc(-c4cccc(OC(F)F)c4)c3O)nc2c1 +CCNC(=O)OCc1c(COC(=O)NCC)c(-c2ccccc2)n2c1Cc1ccccc1C2 +CON=C(C)c1ccc(N2C(=O)c3n[nH]c(C(C)(C)C)c3C2c2ccccc2OC)cc1 +COc1ccccc1N1CCN(CCCOc2ccc3c(c2)SCC(=O)N3)CC1 +CCCN(CCC#N)c1nc(C)nc(N(CC)c2ccc(N(C)C)cc2C)n1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1cccc(CN(C)C)c1 +O=C(c1ccc(F)c(Cl)c1)N1CCC(F)(CNCc2ccc(Cl)cn2)CC1 +COc1ccc2nc3c(c(NCCCCCCNC(=O)C4(C)CCc5c(C)c(O)c(C)c(C)c5O4)c2c1)CCCC3 +O=C(O)Cc1cc(C2CCN(S(=O)(=O)c3cccc(Cl)c3)CC2)c2cc(F)ccc2c1 +Fc1ccc(C(OCCC2CCN(Cc3cc4ccccc4o3)CC2)c2ccc(F)cc2)cc1 +CNC(=O)c1cc2c(Oc3ccc(-c4ccccc4)cc3)cncc2s1 +Oc1nc2ccc(-c3ccc(F)c(F)c3)cc2n1C1CCCC1 +Cc1cc(NCc2c(Cl)cccc2Cl)c2cccc(C(N)=O)c2n1 +CC1CN(Cc2ccccc2)c2ccccc2C(C)N1C(=O)C1CCOCC1 +O=C(NC1CCNC1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(c1ccccc1)c1cc(Cl)ccc1NC(=O)C(c1ccc(F)cc1)N1CCN(CCO)CC1 +CC(C)(C)C1CCC(N2CCC(C(N)=O)(c3ccccc3F)CC2)CC1 +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2Cc2ccccc2C)c1 +O=C(O)CC(=O)NCN1CSC(=S)N(CCCCCCN2CN(CNC(=O)CC(=O)O)CSC2=S)C1 +COc1cc(-c2cc(C(=O)N3CCC(O)CC3)c3c(N)ncnn23)ccn1 +CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(-c3ccccc3OC)cc2F)CC1 +CC(C)CCCc1nc(-c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)no1 +O=C(Nc1nc2cc(F)ccc2n1C1CCC(CO)C1)c1cccc([N+](=O)[O-])c1 +CC(C)=CCC12OC(C)(C)C3CC(C=C4C(=O)c5c(O)cccc5OC431)C2=O +NCCCCN(CC1Cc2ccccc2CN1CC(=O)N1CCOCC1)C1CCCc2cccnc21 +NS(=O)(=O)c1ccc(SCCO)c([N+](=O)[O-])c1 +O=C(O)CSc1cc(NS(=O)(=O)c2ccc3ccccc3c2)c2ccccc2c1O +O=C(O)C=Cc1nc(CSc2c(Cl)cccc2Cl)ccc1OCCCc1ccccc1 +CC(Nc1cc(Nc2ccccc2)ncn1)C(Cc1ccc(Cl)cc1)c1cccc(Br)c1 +N#CC1CCC(Nc2ccc3ncc(-c4cccc(C(F)(F)F)c4)n3n2)CC1 +COc1cc2c(Nc3ccc4nc(N)sc4c3)c(C#N)cnc2cc1OCCCN1CCNCC1 +CNc1nc(-c2cc(OC)c(OC)c(OC)c2)c(-c2ccc(OC)cc2)s1 +O=C1OC2(CCC(c3nc4cc(OC(F)(F)F)ccc4[nH]3)CC2)CN1c1cccnc1F +CN1CCN(c2ccc(Nc3cc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)cc2)CC1 +CC(C)CC(C(=O)NCC#N)c1cccc(-c2cccc(-c3csc(CN4CCNCC4)n3)c2)c1 +CCC1(c2nc3c(C(N)=O)cccc3[nH]2)CCCN1 +CCOc1ccc(S(=O)(=O)N(CC(=O)N2Cc3ccccc3C2C(N)=O)c2ccc(OC)cc2)cc1 +CC(C)Nc1c(C(N)=O)nnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc12 +CC(=O)OCC(Cc1cccc(C(=N)N)c1)C(C=Cc1ccccc1)NC(=O)c1ccc(-c2ccccc2)cc1 +CC(C)N1CCC(Oc2ccc(N3CCN(C(=O)c4ccc(C#N)cc4)CC3=O)cc2)CC1 +O=C(OCC(=O)N1CCC(c2ccccc2)=N1)c1ccc([N+](=O)[O-])s1 +CCOc1cc(C2NC(=O)N=C(c3cnn(C)c3)C2c2ccsc2)cc(C(=O)O)c1O +O=C(c1ccc2[nH]ccc2c1)N1CCC(N2C(=O)OCc3ccccc32)CC1 +Cc1cn(-c2ccc3n(c2=O)CCN(Cc2[nH]c4ccc(Cl)cc4c2Cl)C3=O)cn1 +CCN(CC)C(=O)Nc1cccc(C(Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 +COc1ccc(C2C(C(=O)O)C(c3ccc4c(c3)OCO4)CN2CC(=O)NC(c2ccccc2)c2cc(C)ccc2C)cc1 +CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)cc1 +O=C(O)CC(NC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1)c1cncc(C=Cc2cccc(OCCF)c2)c1 +CC(C)N(c1ccc(Oc2cccnc2)nc1)S(=O)(=O)c1ccc2ccccc2c1 +CC(C(O)c1ccccc1)N(C)S(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1 +O=C(C=Cc1ccc2c(c1)C(=O)N(CCc1ccccc1)C2=O)NO +CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(OC(F)(F)F)cc3)[nH]2)CC1 +O=C(C1=C(O)C(=Cc2cccc(OCCN3CCCC3)c2)CCC1)c1ccccc1 +CCN1CCCC1C(=O)Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1 +CN1CCN(C2=Nc3cc(Cl)ccc3Oc3ncccc32)CC1 +O=C(C=Cc1ccc(O)c(O)c1)c1ccccc1-c1cccs1 +N=C(N)c1cccc(C(=CC(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)Cn2cnnn2)c1 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc5c4OC(F)(F)O5)c3)cc12 +CCC(N)C(=O)NC1CCCCC2CCC(C(=O)NC(c3ccccc3)c3ccc4ccccc4c3)N2C1=O +COC1CCN(c2nccc(Nc3cc4c(cn3)nc(C)n4C(C)C)n2)CC1F +Cc1nn(C(C)C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nnnn4C)CSC23)cc1Cl +Clc1ccc2c(c1Nc1ncnc3cc(OCCc4ccncc4)cc(OC4CCOCC4)c13)OCO2 +CN(CCCCN1C(=O)CCc2ccccc21)Cc1ccccc1 +COc1cc(-c2c3c(cc4c2[nH]c2ccccc24)COC3=O)cc(O)c1O +CN1CC(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)CC2c3cccc4[nH]cc(c34)CC21 +COc1cc(C2c3cc4c(cc3C(Nc3ccc(F)cc3)C3COC(O)C23)OCO4)cc(OC)c1O +COc1ccccc1C(CC(=O)O)NC(=O)CCCCc1ccc2c(n1)NCCC2 +CC(C)(C)OC(=O)NC(Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1CC1CC1 +CCOc1cc(=O)n(C)cc1-c1cc(N(CCc2ccccc2)S(=O)(=O)CC)ccc1Oc1ccc(F)cc1F +O=S(=O)(c1ccc(F)cc1)N1c2ccccc2-c2n[nH]cc2C1C1CC1 +CCCN(CCCCN1CCN(c2ccc(-c3cccc(O)c3)cc2)CC1)C1CCc2nc(N)sc2C1 +CCCN(CC1CC1)c1nc(C)nc(N(CC)c2ccc(N(C)C)cc2C(F)(F)F)n1 +CCNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O +CC(=O)Nc1ccc(-c2ccccc2)n(CC(=O)NC(C(=O)C(F)(F)F)C(C)C)c1=O +NC(=O)C1(c2ccccc2)CCN(C(=O)NC2C3CC4CC(C3)CC2C4)CC1 +OC1CCc2cccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 +NC(=O)Nc1ccc(Nc2cccc(C(F)(F)F)c2)cc1 +O=C(NCCS)C(Cc1cc(Br)cc([N+](=O)[O-])c1)=NO +CCOc1ccc(-n2c(C)c3c(C)nnc(-c4ccc(C)cc4)c3c2C)cc1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(C(F)(F)F)cn2)c1 +O=c1c(-c2ccccc2F)c2ccccn2c(=O)n1CCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1 +Cn1c(SCCC(=O)O)nc2c(Br)c(Br)c(Br)c(Br)c21 +Cc1cc2c3c(c1)C(c1ccccc1)=NC(NC(=O)c1cc(Cl)c(N)c(Cl)c1)C(=O)N3CC2 +COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(C)c2c1 +O=c1[nH]c(Cc2ccccc2-c2ccco2)nc2c1cnn2C1CCOCC1 +Cc1cccc(C)c1Oc1ccc(C(=O)N(Cc2ccccc2)Cc2ccc(C(=O)O)cc2)cc1 +Cc1ccc(-c2noc(C3CC(n4cncn4)C3)n2)cc1NC(=O)c1cnc2ccccn12 +Oc1ccc2c(c1)C1(CCCCc3ccccc3)CCN(CCc3ccccc3C(F)(F)F)CC1O2 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C(F)(F)F)nn3)c2)c2cnccc21 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(CNCC4CC4)o3)nc2n1 +COc1cc(-c2cccc(C(F)(F)F)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ncccn3)c(F)cc21 +NC1(c2ccc(-c3ncc4ccccc4c3-c3ccccc3)cc2)CCC1 +c1cc(C2CNCCO2)ccc1Nc1ccc(C2COC2)cn1 +CNC(=O)Nc1ncc(SC2CCOCC2)cc1Oc1cccnc1C +Cc1nc(NC2CCCOC2C)nc(-n2ccnc2C)c1[N+](=O)[O-] +Cc1c(CN(CCCCc2ccccc2)C2CCN(C(=O)c3cccc4ccccc34)CC2)c(=O)n(-c2ccccc2)n1C +Cc1cc2nc(CC(N)C(=O)O)c(CP(=O)(O)O)nc2cc1C +Cc1cccc(C)c1C(=O)N1CCC(N2CCC(N(Cc3ccccc3)C(=O)C3CC3)C2)CC1 +CCOC(=O)N1CCC(N=C(NC#N)N2CCC(=C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1 +COc1ccc(Nc2nc(-c3cccc(C(=O)Nc4ccc(-c5ncc[nH]5)cc4)c3)cn3ccnc23)cc1OC +CCCOCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)c(C)c12 +C=C(Br)C(=O)Nc1cccc(C=C2CCCC(=Cc3cccc(NC(=O)C(=C)Br)c3)C2=O)c1 +CCCn1nc(-c2ccc(OCCCN3CCCC3C)cc2)c2sccc2c1=O +Cc1ccc2c(c1Br)C(=NNC(=O)Cc1ccc(O)cc1)C(=O)N2 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2cnccn2)CC1c1ccccc1 +O=C(N=S(=O)(CCCO)CCCO)c1cncc(C#Cc2cccc(NC(=O)c3ccc(Cl)c(C(F)(F)F)c3)c2)c1 +CCc1nc(N)nc(-n2c(Nc3cccc(O)c3)nc3ccccc32)n1 +CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2ccccc21 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+O=c1cc(-c2ccccc2)oc2cc(OCCCCN3CCN(CCNc4c5c(nc6ccccc46)CCCC5)CC3)ccc12 +CCOc1cccc(CN2CCN(Cc3cc4ccccc4o3)CC2)c1 +Fc1ccc(-c2ncn(C3CCNCC3)c2-c2ccnc(Oc3ccc(-c4ccccc4)cc3)n2)cc1 +CCCC(CC)n1ccc2cc(C(C)=CC(=O)Nc3ccccc3OCCCC(=O)O)ccc21 +COc1cc2c(ccn2-c2cccc3ncccc23)c(OC)c1OC +CCc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(=O)(=O)CC)cc2)cn1C(C)C +Nc1cnc(-c2ccc(-c3ccc(C(F)(F)F)cc3CN3CCOCC3)cc2F)cn1 +CN1CCCCC1Cn1cc(C(=O)c2cccc3ccccc23)c2ccc(I)cc21 +COCC(=O)N(C)Cc1cccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)c1 +CC1=C(F)CN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CC4CC3CO4)n2)C1 +COc1ccc(CCN(C)CCCOc2ccc(S(=O)(=O)c3c(C(C)C)oc4ccccc34)cc2)cc1OC +CC(c1ccccn1)N(CCCCN)Cc1ncccc1C(C)(C)C +CCNC(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(CC(CC)CC)CC3)cc(Oc3ccc(F)cc3)c2)cc1 +CC(C)(C)c1ccc2ncn(CC(=O)CC3NCCCC3O)c(=O)c2c1 +COc1ccc(CN2CC3CCC(=O)C2CN3CC=C(C)C)cc1 +CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CCN(c2ncccn2)C3)cc1 +C=COC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)CCCNC(=O)OCc1ccccc1)C(C)C +Cc1ccccc1C1CCc2c(C(=O)N(C)C)cn3c(C)c(C)nc3c2O1 +CCCc1cc(N)c2cc(NC(=O)c3ccc(-c4ccc(C(F)(F)F)cc4)cc3)ccc2n1 +COC(=O)C1=C(C)CC(C)=C(C(=O)OC)C1c1ccc(Cl)c(C(F)(F)F)c1 +COc1ccc(-c2ccc(OCc3cc(C(=O)NS(=O)(=O)c4ccccc4C)oc3C)cc2)nc1 +O=C(O)CCN1C(=O)C(=Cc2ccc(Cl)cc2Cl)SC1=S +CCC(CC)C(=O)OC1C(C)=CC23C(=O)C(C=C(CO)C(O)C12O)C1C(CC3C)C1(C)C +CCCCC(NC(=O)OC(Cn1cnc(-c2ccc(C(F)(F)F)cc2)c1)C(C)(C)C)C(=O)C(=O)Nc1nccs1 +CCN(CC)CC(Cc1ccccc1)Nc1ccncc1S(=O)(=O)NC(Cc1ccc(N)cc1)C(=O)N1CCC(CCF)CC1 +O=C(c1ccc2ncccc2c1)N1CCC(N2CCC(Cc3ccc(Cl)c(Cl)c3)C(CF)C2)CC1 +O=C(Nc1ccc(-c2ccc(Cl)c(Cl)c2)cc1)C1=C(O)c2ccc(O)cc2S(=O)(=O)N1 +CCOc1ccc(Cc2cc3c(cc2Cl)OCCCCOCC2OC3C(O)C(O)C2O)cc1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(=O)[nH]c2)c1 +N#Cc1ccc(Cl)c(Oc2ccc(S(=O)(=O)Nc3ccc(F)cn3)cc2C#N)c1 +CN1CCC(c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1=O +COC12CCC3(CC1COCc1ccccc1)C1Cc4ccc(NC(C)=O)c5c4C3(CCN1C)C2O5 +Cc1cc(C)cc(C(CC(C)C)NC(=O)c2cc(COc3ccccc3F)ccc2CCC(=O)O)c1 +O=C(C=Cc1ccc2c(c1)C(=O)CC1(CCN(C(=O)c3ccccc3)C1)O2)NO +Cc1cc(-c2ccc(C(=O)Nc3ccccc3C(=O)O)cc2Oc2ccccc2)ccc1F +OC(COc1cccc2[nH]ccc12)CN1C2C=C(c3ccc4ccccc4c3)CC1CC2 +Cc1cc(C)nc(OCC(=O)Nc2cc(-n3nc(C)cc3C)nc(-c3ccc(C)o3)n2)n1 +CC(C)c1cc(C(=O)N2CCC(NC(=O)C(C)(C)C)C2)n[nH]1 +COC(=O)CCCCCCCNC(=O)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)cc1 +O=C(Nc1ccc(-n2ccc3c(NC(=O)c4ccccc4)nccc32)cc1)c1ccc(N2CCOCC2)c(C(F)(F)F)c1 +O=C1Nc2ccc(-c3csc(C4CCNCC4)n3)cc2C1=Cc1cc2ccccc2[nH]1 +CCOc1c(C(C)=CC=CC(C)=CC(=O)O)cc(C(C)(C)CC)cc1C(C)(C)CC +CC(C)CC(NC(=O)c1ccc(-c2ccccc2)cc1)C(=O)NC1COCC1=O +Cn1c(-c2ccc3nccnc3c2)c(-c2ccc3nonc3c2)c(=O)n1C +O=C(c1ccccc1)C1CCN(CC(O)COc2cccc3[nH]c4ccccc4c23)CC1 +O=C(NC1CCNC1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +Oc1ccc(CCNc2nc(SCCOc3ccc(Cl)cc3)nc(N3CCNCC3)n2)cc1 +CS(=O)(=O)N1CCCC(n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)C1 +CNC(=O)C(Cc1ccccc1)NC(=O)C(CCCCCCc1ccccc1)CC(=O)NO +N=C(NO)c1cccc(N2C(=O)N(c3cccc(C(N)=CO)c3)C(Cc3ccccc3)C(O)C2CCc2ccccc2)c1 +O=C(NC1CCCCC1)c1ccc(OCc2ccccc2)nc1 +O=C1Nc2ccc(S(=O)(=O)Nc3ccc(N4CCOCC4)cc3)c3cccc1c23 +CN1CCN(c2ccc(-c3ccc4[nH]c5nccc(-c6ccc(C(=O)c7ccccc7)cc6)c5c4c3)cc2)CC1 +N#CNC(=NC1CC1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +COc1cccc(CCn2c3c(c4c2-c2ccccc2C4=O)C(=O)CCC3)c1 +N#CC1CCCCC1n1cc(C(N)=O)c(Nc2ccc(F)c(Cl)c2)n1 +CS(=O)(=O)c1ccc2c(c1)CCC1(CCN(C(=O)c3ccc(C(F)(F)F)cc3)CC1)O2 +CCc1ncnc(-c2ccc(C(=O)N(C)OC)c(F)c2)c1C#Cc1ccc(N)nc1 +CCOc1cc(CN2CCC(NC(=O)c3cncc(C)c3)CC2)cc(OCC)c1F +CCCNC(=O)Nc1cccc(-c2ccc(CC(NS(=O)(=O)c3cccc(Cl)c3Cl)C(=O)O)cc2)c1 +Cc1c(-c2nnc(C(C)(C)C)s2)nc(-c2ccccc2Cl)n1-c1ccc(Br)cc1 +O=C(NC1CCN(Cc2ccccc2)C1)c1cccc(-c2cccs2)c1 +CCN1CCN(Cc2cnc(-c3ccc(C(=O)Nc4ccccc4N)cc3)c(F)c2)CC1 +CCN(CC)CCCOc1cc2c(cn1)C(c1ccccc1)CN(C)C2 +CC(=O)c1c(-c2ccccc2)nn(C)c(=O)c1NCCN1CCN(c2ccccc2Cl)CC1 +CCc1cc(-c2ccccc2)cc(CC)[n+]1CC(=O)OCCc1ccc(S(N)(=O)=O)cc1 +CC(NC(=O)C1CC1)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1NC1CCC(O)CC1 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5ccc(F)cc5F)nc4)cccc3c2F)CS1(=O)=O +CN(C)CCn1cnnc1-c1cc(Oc2ccc(NC(=O)NN=Cc3c(Cl)cccc3Cl)cc2F)ccn1 +CCS(=O)(=O)c1ccc(Oc2cc(OC(C)CO)cc(-c3nccc(=O)[nH]3)c2)cc1 +CC(C)c1nn(-c2nc3ccccc3s2)c(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +CC(F)(F)Cn1cnc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc2c1=O +Cc1cc(-c2ccc(CO)o2)cnc1C1(F)CCN(C(=O)Nc2ccc(C(F)(F)F)c(Cl)c2)CC1 +Fc1ccc(CCCN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 +CCCCCCCCCCCCCCC1=C(O)C(=O)C=C(OC)C1=O +CC(C)S(=O)(=O)N1CCC(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CC1 +Cc1[se]c(C=C2C(=O)Nc3cc(-c4cccc(O)c4)ccc32)cc1C(=O)NCCN(C)C +Cc1nc2ccc(F)c(-c3cc4c([nH]3)CCNC4=O)c2nc1NC1(C)CC1 +O=C(Nc1ccc(C(F)(F)F)cc1)N1CCCC1c1ncnn1Cc1ccc(Cl)cc1 +O=C(OC1(C2COCC(CC3CC3)N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CC2CCC(C1)N2CCO +CCCC(CCC)C1C(C(=O)c2ccc(CO)cc2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +ON=CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CCCCCc1ccc(C(=O)OC2CCC(NC(=O)C(OC)C(O)C(O)C(O)C=CC(C)(C)C)C(=O)NC2)cc1 +N#Cc1ccc(OCCCN2CCC(C(O)(c3ccccn3)C3CCCC3)CC2)cc1 +CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)(F)C2)CCN1Cc1ccc(Cl)c(Cl)c1 +O=C(O)C1CC(NC(=O)N(c2ccccc2)c2ccccc2)c2c(Cl)cc(Cl)cc2N1 +CCc1nc(-c2ccccc2)c(-c2ccccc2)n1CCCCCCCC(=O)OC +O=C(NCc1ccno1)c1cnc(Oc2ccc3c(c2)CCC(c2cccc(F)c2)O3)s1 +CN(C)CC(Cc1ccccc1)c1cc(OCCNS(=O)(=O)c2cn(C)cn2)ccc1F +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)cc1C(=O)O +Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(F)c2cnc3ccccc3c2)CC1 +O=C1Cc2c([nH]c3ccc(F)cc23)-c2ccccc2N1 +Cc1cc(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C(C)C)n2)c(OC2CC2)cc1C1CCN(C(C)C)CC1 +N#CCCn1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1 +CC(=O)NC(Cc1ccccc1)C(=O)OCc1cc(C)cc(C)c1 +O=C(CCCN1CCCC1)Nc1n[nH]c2nnc(-c3ccccc3)cc12 +CN(C)c1ccc(C(c2c(O)oc3ccccc3c2=O)c2c(O)oc3ccccc3c2=O)cc1 +CCOC1CN(c2cccc(-c3cccc(C)c3OCc3cc4c(c(OC)c3)CN(C3CCOCC3)CC4)n2)CCC1C(=O)O +COC(=O)c1cccc2c1nc(Nc1c(C)cccc1Cl)c1cncn12 +OCc1cc(C(O)CNCCc2ccc(NCC(O)c3ccc(O)cc3)cc2)ccc1O +COc1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)c(CO)c1 +Fc1cccc(CNc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)c1 +CCOc1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +O=C(NCCc1ccccc1)Nc1ccc2cc(C(=O)NC3CN4CCC3CC4)sc2c1 +OCC#Cc1cn2c(-c3ccc(-c4cnc(C5CC5)[nH]4)cc3)cnc2c(NCCCCO)n1 +Cc1ccc(OCC(=O)N(Cc2cccs2)C(C)C)cc1 +COc1cc(Cc2nc(-c3ccccc3)c[nH]2)cc(OC)c1OC +CC(C)NC(=O)c1cc(F)ccc1CNC(=O)c1nc(C(C)(C)C)n(C)c(=O)c1O +CN1CCN(c2ccc(-c3cncc(-c4ccc(C(=O)NS(C)(=O)=O)cc4)n3)cc2)CC1 +Cc1cc2scnc2cc1-c1ccc(C(=O)Nc2ccccc2F)s1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)C(C)(C)C)CCO1 +COc1cc(O)c2c(=O)cc(-c3ccc(O)c(O)c3)oc2c1O +CC(=O)NC1CC2(CCN(Cc3ccc4[nH]c5ccccc5c4c3)CC2)c2ccccc21 +CCCCN(CC)c1nc(C)nc2c1n(C)c(=O)n2-c1ccc(C(C)C)cc1Br +CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCN2C3=O)CC1 +O=C(CCN1CCCC(n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)C1)N1CCC(F)(F)C1 +COc1cccc(CNC(=O)c2cn(C)c3nc(-c4cn[nH]c4)ccc23)c1 +CC12C=CC(=O)C=C1CC(Cc1ccccc1)C1C2CCC2(C)C(=O)CCC12 +CCC(C(=O)NC(CC(=O)O)C(=O)CNCCCc1ccccc1)n1cccc(NC(=O)c2ccc3ccccc3c2)c1=O +O=C(NC1CCCCC1O)c1cn(Cc2ccc(-n3cccn3)cc2)c2ccccc12 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-c3nc4ccccc4[nH]3)ccc(F)c12 +COC(=O)c1ccccc1-c1ccc(CNc2ncccc2NC(=O)CC(F)(F)F)cc1 +N=C(N)c1ccc(-c2cc(-c3cncc(C(=N)N)c3)on2)cc1 +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccc(Cl)nc4c3)CC1)C2 +CC(C)(C)c1cccc(CNC2C[S+]([O-])CC(Cc3cc(F)c(N)c(OC(CO)C(F)(F)F)c3)C2O)c1 +Cc1ccc(C2=C(NC(=O)c3cnccn3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +CN(CCc1ccccc1)C(=O)c1cc(N)c2nc(-c3ccc(Br)o3)nn2c1 +CCCN(C(=O)OCc1cccc(C)c1)C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1 +O=C(O)c1ccccc1C(=O)C=Cc1ccc(OCc2ccc3ccccc3n2)cc1 +COCC(C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +Cc1nc2ccccc2nc1OCc1cc(OC2CCOCC2)nc(N2CCCC2)n1 +O=C(NC1CCN(CCOc2cccc(-c3ccccc3)c2)C1)c1cccc(F)c1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCC3CCOCC3)c12 +Fc1ccc(C(OCCC2CCN(CCc3ccccc3)CC2)c2ccc(F)cc2)cc1 +C(#Cc1cc(-c2n[nH]c3c2Cc2cc(CN4CCSC4)ccc2-3)cs1)COc1ccccc1 +CS(=O)(=O)N1CC2(CCN(C(=O)Nc3cn(-c4cccc(F)c4)cn3)CC2)c2ccccc21 +COc1cc(C=CC(=O)NO)ccc1OCC(Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1F +COc1cc(-c2nc(-c3cc(C)nc(C(F)F)c3)c3n2CC(C)OCC3)ccc1OC(F)F +NC(CC(=O)N1CCCN(c2ncccn2)CC1)Cc1cc(F)c(F)cc1F +Cc1noc(C)c1C(=O)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +N#Cc1ncc2nc1OCCC=CCOc1ccc(OCCCN3CCOCC3)cc1NC(=O)N2 +CC1(c2nc(NC(=O)c3ncc(OCCF)nc3N)ccc2F)N=C(N)OCC1(F)F +Cc1cccc(CNc2nc(C)nc(C(F)(F)F)n2)c1 +CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(-c4cnn(CCOC)c4)c2)CC3)n1 +O=C(O)CCCC=CCC1C2CCC(C2)C1NS(=O)(=O)Cc1ccccc1 +CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(N(C)CC(N)=O)cc1OCC2 +CN(C)CC(c1ccc(C(F)(F)F)cc1)N1CCN(c2ncnc(N)c2Br)CC1 +Oc1ccc2c3c1OC1C(O)C=CC4C(C2)N(C2CCCCCC2)CCC341 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccnc(F)c3)cc2s1)S(=O)(=O)CCC(F)(F)F +CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(C)c3)ncn2)c1 +Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +CC(C)(C)OC(=O)N1CCC(c2cccc(Nc3nc4c(-c5ccc(S(C)(=O)=O)cc5)cccn4n3)c2)C(O)C1 +CC1CNC(=O)c2[nH]c3ccc(C(=O)Nc4ccc(C(N)=O)nc4)cc3c21 +Cc1ccccc1-c1nc(-c2nc3ccccc3[nH]2)c(N2CCN(C(=O)Cn3cnc4cccnc43)C(C)C2)s1 +O=C(O)c1sc(-c2ccccc2)cc1N1C(=O)CCCC1C1CCCCC1 +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(S(C)(=O)=O)c3)cc2N=C(N)C1 +CNS(=O)(=O)Nc1cccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1C +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(N3CCN(C)CC3)cc12)C(=O)O +COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(=O)OC)CC2)C1c1ccc(F)c(F)c1 +COc1ccc(CC(=O)OCC(=O)Nc2c3c(nc4ccccc24)CCCC3)cc1OC +CCC(CO)Nc1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +O=C(Cc1ccccc1)Nc1nnc(OC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 +CCCc1c(COc2ccc(C(C)c3nnn[nH]3)cc2)ccc(C(C)=O)c1O +CC(=Cc1nc(C(=O)O)c[nH]1)c1cc2c(cc1C)C(C)(C)CCC2(C)C +O=c1cc(C2CCCCC2)oc2ccc(OCCCCCCN3CCC(O)CC3)cc12 +Cc1cn(C2CC(N=[N+]=[N-])C(COP(=O)(O)OCCOc3ccc4ccccc4c3)O2)c(=O)[nH]c1=O +COc1cc(OC)cc(C(=O)N(C)CCCNc2ccnc3cc(Cl)ccc23)c1 +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)C2C4CC6CC(C4)CC2C6)CCC3(O)C1C5 +Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(C(F)(F)F)cc4)c3Cl)cccc2s1 +O=C(Nc1ccc2c(c1)CN(C(=O)c1ccccc1)C2)N1Cc2ccccc2C1 +CC(C)COC(=O)C(Cc1ccccc1)NP(=O)(COC1C=C(F)C(n2cnc3c(N)ncnc32)O1)Oc1ccccc1 +CC(C)CCN1C(=O)C(NC(=O)Nc2ccc(Cl)cc2)C(=O)N(CCN2CCOCC2)c2ccccc21 +CC(C)(C)c1nc(-c2ccn[nH]2)c2c(N)c(C#N)c(N)nc2n1 +CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(N)Cc2ccc(F)cc2)C(CCNc2ccccn2)C1=O +CC(=NOCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cc1 +CCCCCC1=CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 +CCCCCCCCCCCCCCCC(=O)OC(COC(=O)CNCCCOCCOCCOCC)CSCC(N)C(=O)NC(CO)C(=O)O +O=C(Nc1ccncc1-c1ccccc1)N1CCN2C(=O)N(C3CC3c3ccccc3)C(=O)C2C1 +CC(C)c1ccc(-n2nnnc2C(NCC2CCCCC2)c2c(C(=O)O)[nH]c3cc(Cl)ccc23)cc1 +O=C(Nc1cc(-c2ccccc2)[nH]n1)c1ccc2cc3n(c2c1)CCCNC3=O +COc1ccc(Cn2c(CCc3ccccc3)nnc2C(NC(=O)C(C)(C)N)c2c[nH]c3ccccc23)c(OC)c1 +C=C(Cl)COc1cc(-n2nnc3c(cnn3C)c2=O)c(F)cc1Cl +Cn1c(-c2nnc(N)s2)nc(Br)c1[N+](=O)[O-] +COC(=O)C(Oc1nc(OC)cc(OC)n1)C(C)(Oc1ccc(C(C)C)cc1)c1ccccc1 +O=C(Nc1nc2cccc(-c3ccc(NS(=O)(=O)C4CC4)cc3)n2n1)C1CC1 +CCn1cnc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5)cc4F)c3s2)c1 +CN(C)C=CC(=O)c1c[nH]c2ccc(-c3cncc(NCCN(C)C)n3)cc12 +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccc(Cl)cc1Cl +COc1cc(N(CCCNCC(F)(F)F)c2ccc3ncc(-c4cnn(C)c4)nc3c2)cc(F)c1F +COc1cccc(F)c1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C +CC(C)(C)c1cc(C=C2CCN(c3cccnc3)S2(=O)=O)cc(C(C)(C)C)c1O +CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4ccccc4)c(=O)n(C)c3n2)cc1 +CCc1c(-c2ccccc2)ncn1CCCOc1cccc(C)c1NC(=O)NCCC(C)C +Cn1nc(C(C)(C)C)cc1C(=O)NC(Cc1cccc(-c2nncs2)c1)C(=O)NCC#N +Cc1ccc(-c2ncc(Cl)cc2-c2ccc(S(N)(=O)=O)cc2)cn1 +NC1=NC(c2cccc(OCc3ccccc3)c2)N(c2ccc(Cl)cc2)C(N)=N1 +Cc1cc(C(=O)Nc2cccc(C(C)N3CCC(C(=O)NC4CCCCC4)CC3)c2)ccn1 +O=C(O)CC1C(=O)N(Cc2ccc(Br)cc2F)C(=O)c2ccc(F)cc21 +NNC(=O)c1[nH]c2ccc(S(N)(=O)=O)cc2c1-c1c(F)c(F)c(F)c(F)c1F +C=CCC1(C(=O)Nc2cccc(OC(=O)N(C)C)c2)CCN(c2ncnc3[nH]cc(C)c23)CC1 +CC(C(=O)NC1CC1)c1ccc(OC2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 +CNc1ccc(Nc2ncnc3cc(-c4ccccc4)sc23)cc1 +Cc1ccc(C(=O)NC2CCOCC2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +Cc1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CCCNCC3)n2)sn1 +Cc1ncc([N+](=O)[O-])n1CCOC(c1ccccc1)c1cccnc1 +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(C)c(OC)sc4c3=O)CC21 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1cc(C)ccc1Cl)CC2 +O=C1CCc2ccccc2N1CCCCN1CCN(c2ncccn2)CC1 +CCc1c(Sc2cc(C)cc(C)c2)n(CCC2CCCC2)c(=O)[nH]c1=O +O=C(NCC(c1ccc(C(F)(F)F)nc1)N1CCOCC1)C1COc2ncccc21 +O=C(NCc1ccc(F)cc1)c1c(Nc2ccc(-c3ccccc3)cc2)[nH]c(=O)n(O)c1=O +CN(C)CCCN=C1CC(c2ccc(Cl)cc2Cl)Cc2nc3ccc(Cl)cc3c(O)c21 +CNCCNc1ccc2c(cc1=O)C(NC(C)=O)CCc1cc(OC)c(OC)c(OC)c1-2 +COc1cccc(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)c1[N+](=O)[O-] +CCCN(CCC)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(Cl)cc12 +CNC(=O)c1ccc(F)c2c(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12 +CC(Nc1nccc(N(C(=O)Nc2ccccc2Cl)c2ccccc2)n1)C(C)(C)O +CC(C)c1cc(CN(C)C(=O)NCC23CC4CC(CC(C4)C2)C3)no1 +Cc1noc(-c2ccc3c(c2)c2c(n3CCCSc3cc(F)cc(F)c3)CCCC2)n1 +O=C(NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1)c1ccccc1 +COc1cc(Cn2cnc3cc(C#CCCO)cnc32)ccc1OCc1ccc(C(F)F)nc1 +CC1CCCN1CCc1ccc(C2=CCC3CN(Cc4ccccc4)CC23)cc1 +O=C(NC1CC1)c1ccc(CN(C2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 +CC(c1ccc(Cl)c(Cl)c1)C(NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(=O)O +NCc1ccnc(Oc2cccc(C(=O)Nc3ccc(C(=O)O)cc3)c2)c1 +FC(F)(F)C(F)(F)CNCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)S(C)(=O)=O)n2C)CC1 +Clc1ccc2c(NCc3nc(-c4ccccc4)cs3)ccnc2c1 +O=C(CC(CCCc1ccc(F)cc1)C(=O)NC(CC1CCCCC1)C(=O)NCCc1ccccc1)NO +CCC(=O)c1c2c(nc3ccccc13)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC +CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2ccc(OCC(F)F)c(C(=O)Nc3ccc(Br)cc3)c2)c1 +COC(=O)C1=C(Nc2ccc(OC)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O +C=CC(=O)Nc1cccc(N2C(=O)N(C)Cc3cnc(Nc4ccc(N(C)C)cc4OC)nc32)c1 +NS(=O)(=O)c1ccc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)cc1 +COc1ccc(-c2nc(CSc3ccc(OCC(=O)O)c(C)c3)oc2-c2ccc(OC)cc2)cc1 +CC(C)n1c(=O)n(C(=O)NC2CC3CCCC(C2)N3C)c2ccccc21 +Cc1cc(Oc2ccc3cc(C#N)ccc3c2Br)nc(Nc2ccc(C#N)cc2)n1 +COc1ccc(S(=O)(=O)Nc2cc(-c3cnc4nc(N)nc(C)c4c3)cnc2OC)cc1 +COc1ccccc1N1CCN(CCNC(=O)OC(C)(C)C)CC1 +COc1cc(O)cc(N(CCN)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(CCCCCO)[nH]c(=O)c12 +N#CCNC(=O)CNC(=O)C(Cc1ccccn1)NC(=O)Cc1cc(Cl)cc(Cl)c1 +CCCC(CCN1CCCC(Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(-c2nnnn2C)cc(C(C)(C)O)c1 +COc1cc2c(cc1OC)C(c1ccccc1[N+](=O)[O-])N(CCOc1ccccc1)CC2 +COC1CCN(Cc2ccc(C#Cc3ccc4c(c3)CCC4NC(C(=O)NO)C(C)O)cc2)CC1 +O=C(O)c1cccc2c1nc(Nc1ccccc1Cl)c1ccsc12 +O=Cc1cc(-c2ccc(C(=O)N3CCOCC3)cc2)cc(C(F)(F)F)c1O +Cc1nc2ccccc2c(Nc2ccc(N3CCN(C)C(C)C3)cc2)c1C(C)O +COc1cccc2c1c(C(=O)C=C(O)C(=O)O)cn2Cc1ccccc1F +O=C(c1nc2cccc(Cl)c2[nH]1)N1CC(c2nccnc2-c2cccnc2)C1 +CC(c1ccc2c(c1)CCO2)N(Cc1ccc(OCCN2C(=O)CN(C)C2=O)c(Cl)c1)CC1CCC(C(=O)O)CC1 +Cc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C2CCCO2)n1 +CN(C)CCN(CCNCCc1ccc(O)c2[nH]c(=O)sc12)C(=O)CCOCCc1ccccc1 +Cc1[nH]c(-c2ccccc2Oc2ccccc2)cc1C(N)=O +COc1cccc(NC(=O)c2ccc(Nc3nc(Nc4ccc(O)cc4)ncc3F)cc2)c1 +COc1ccc(CN2CCCN(CC3CCCCC3)CC2C)cc1 +CC1CC2C(OC(=O)NC(Cc3ccccc3)C(O)CN3CC4CCCCC4CC3C(=O)NC(C)(C)C)COC2O1 +Cc1nnc(SCc2nc(-c3ccc(Cl)cc3)no2)n1-c1ccc(F)cc1 +COCCNCc1c(C(=O)NC2CCCC(O)C2)noc1-c1ccc(C(F)(F)F)cc1 +COc1cc(-c2onc3c2CCCN3Cc2ccc(F)cc2)ccc1-n1cnc(C)c1 +CN(C)Cc1ccc(CCN2CCn3nc(C(=O)Nc4ccc(F)cc4)cc3C2=O)cc1 +CCNc1ncc2nc(Nc3ccccc3F)n(C3CCCC3)c2n1 +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(O)c1 +CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CCC(C)=CC21 +CN(C)CCCN1c2ccccc2CCc2ccc(C#CCOCCCOc3cccc4ccccc34)cc21 +CNC(=O)C(NC(=O)C(CC(C)C)C(NC(=O)c1cccnc1)C(=O)NO)C(C)(C)C +[H]C([H])([H])OC(=O)c1cc2c3ccccc3nc-2c[nH]1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2Cc3[nH]ncc3C1CC(c1nc[nH]n1)C2 +NC(=NO)c1ccc(NC(=O)CCNCCc2ccccc2)cc1 +O=c1cc(NCCCNCc2ccc(Cl)c(Cl)c2)[nH]c2ccccc12 +CN1CCC(c2ccc(CN(C)Cc3ccc(Cl)cc3)cc2)CC1 +CCOC(=O)N1CCC(c2ccccc2OC)(S(=O)(=O)c2ccc(Cl)cc2)CC1 +COc1ccc(CNc2c(CO)cnc3c(N(C)C)cc(C#N)cc23)cc1Cl +O=C1c2ccccc2C(=O)c2c(-c3ccc(OCCN4CCOCC4)cc3)noc21 +COC1CCC2(CC1)Cc1ccc(-c3cc(F)ccc3C)cc1C21N=C(N)N(C)O1 +O=C(Nc1cccc(F)c1)c1c(O)c2ccc(F)cc2[nH]c1=O +O=C(O)CC(NC(=O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O)C(=O)O +CCN1CCN(C(=O)Nc2cccc3ccccc23)CC1C(C)Nc1nccc(-n2cnc3ccccc32)n1 +O=C(c1ccc(Oc2ncccc2-c2ccnc(F)c2)cc1)c1nc2ccccc2[nH]1 +COC(=O)c1cccc(-c2ccc(O)c(C=O)c2)c1 +Cc1sc(NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3)c(C(N)=O)c1C +COc1cc(C(=O)c2ccn(-c3cccc(N)c3)c2)cc(OC)c1OC +CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NCC#N +CCc1ccc(-n2c(C(CC)N(CCc3ccccc3)C(=O)c3cc(OC)cc(OC)c3)nc3ccccc3c2=O)cc1 +COc1ccc(C(=O)CC(Nc2ccc([N+](=O)[O-])cc2)C2CCCCC2)cc1 +CC(C)(C)OC(=O)NCCCCCNC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccccc1 +CN(C)Cc1cccc(-c2[nH]c3cccc4c3c2CCNC4=O)c1 +CC(=O)N1CC(NC(=O)C=Cc2ccccc2)CC1C(=O)NO +CCc1ncc(Cc2cnc3ccc(N)cc3c2)c2cc(OC)c(OC)cc12 +Cc1ccc(-n2cnc3c(sc4cncc(N(C)C)c43)c2=O)cc1 +CN(C)c1ccc(Nc2c3cc(NC(=O)CCN4CCCC4)ccc3nc3ccc(NC(=O)CCN4CCCC4)cc23)cc1 +COc1ccc2[nH]nc(C(=O)NCC3CCN(Cc4nc(C(=O)O)cs4)CC3)c2c1 +O=C1NC(=O)C(CN2Cc3ccc(F)cc3C2=O)(c2ccc(-c3c[nH]c(=O)c(Cl)c3)cc2)N1 +CC(C)(N)CNc1nc(-c2ccncc2F)cc2cnccc12 +CCCCCCCCCCC=Cc1ccccc1C(SCCC(=O)O)SCCC(=O)O +O=C(NO)C1(S(=O)(=O)c2ccc(Oc3ccc(C(F)(F)F)cc3)cc2)CCNCC1 +CC(=O)c1ccc(Nc2ccc(Cl)cc2)c(C(=O)O)c1 +c1ccc(N2CCN(CCCNC3=Nc4ccccc4OC3)CC2)nc1 +O=C(c1ccc(NCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +CC(NC(=O)c1c(Cl)cccc1Cl)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1 +CC(C)N1CCC(CNc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 +O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc(Cl)cc1 +CNC(=O)n1cc(NC(=O)N2C(C(=O)NC(COC)c3cccc(Cl)c3F)CC3CC32)c2ccccc21 +Cn1c(=O)c2c(nc(SCCCc3ccccc3)n2C)n(C)c1=O +COc1cc2ncnc(N3CCCC(c4ccccc4)C3)c2cc1OCCc1ccccn1 +CCCOc1ccc2[nH]c3c([N+](=O)[O-])ccc4c3c(nn4CCN(CC)CC)c2c1 +C1=C(Cc2ccc(-c3ccccc3)cc2)C2CCN1CC2 +COc1cc(C(CC=C(C)C)OC(=O)C2CCCO2)c(OC)c2c1C(=O)C=CC2=O +[O-][S+](CC1(O)CCN(CCc2c[nH]c3ccc(F)cc23)CC1)c1ccccc1 +Cn1c(-c2ccc(Cl)cc2)c(CCC(=O)N2CCC(O)(Cc3ccccc3)CC2)c2cc(-c3cccnc3)ccc21 +O=C(NO)C1(F)C(c2ccccc2)C1c1ccc(-c2ncc(Cl)cn2)cc1 +O=C(NCCCn1ccnc1)c1ccc(NCc2cc(Cl)cc(Cl)c2)nn1 +COc1cc(C2C(C#N)=C(N)Oc3c2ccc2cnccc32)cc(OC)c1OC +Cc1ccc(Cn2c(=Nc3ccc(OC(C)C)c(F)c3)[nH]c(=O)n(CCC(=O)O)c2=O)cc1 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+Cc1c(NC2CCN(Cc3ccccc3)CC2)ccc2c(=O)n(-c3cccc(Cl)c3)c3nncn3c12 +N#Cc1ccc(N2CCC(O)(c3ccc(F)cc3)C2)cc1Cl +Cc1ccc(-c2ccc(Cn3c(CC(C)(C)C(=O)O)c(SC(C)(C)C)c4cc(OCc5ccccn5)ccc43)cc2)nn1 +Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=O)c5sc(-c6ccccc6)nc5-c5ccccc5)cc4F)c3s2)c1 +COCCOc1cncc(-c2nnc3c(C)nc4ccc(CN5CCOCC5)cc4n23)c1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1cnc(N2CCOCC2)nc1 +CCCNC(=O)OCC(C1CC1)n1cc(Cl)nc(Nc2cc(C)c(OC)nc2C)c1=O +N=C(N)Nc1ccc(C(=O)NCCC(=O)NC(CC(=O)O)C(=O)NC(Cc2ccccc2)C(=O)O)cc1 +NC(=O)c1cc2cc(C3CCCC3)c(C(F)(F)F)nc2nc1N +CCOc1ccc(Cc2cc(C3OC(OC)C(O)C(O)C3O)ccc2C)cc1 +CC(O)(c1ccc(C(=O)N(C2CC2)C2CCC(COC(N)=O)(c3ccccn3)CC2)cc1)C(F)(F)F +CCc1cc2c(c(CC)n1)CCC(=O)N2Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 +CCCNC(=O)N1C(C)C(c2ccc(-c3cccc(F)c3)cc2)C1C#N +CC(NC(=O)CCc1nc2ccccc2c(=O)[nH]1)c1ccc(-n2ccnc2)cc1 +CC(C)(C)c1ccccc1N1CCN(C(=O)Cc2nnn[nH]2)CC1 +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)N(CC(=O)O)Cc3ccccc3)cc12 +O=C1NC2=NC3CCCC3N2c2nn(Cc3ccc(C(F)(F)F)cc3)c(Nc3ccccc3)c21 +Oc1cc2c(cc1Br)CCN(CC=Cc1ccccc1)CC2c1ccccc1 +O=C(Nc1ccsc1-c1ccccc1)OC12CCN(CC1)CC2 +c1ccc(-c2nc(NCCc3[nH]cc4ccccc34)c3ccccc3n2)nc1 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN1CCCCCC1 +OCC1OC(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C(O)C1O +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCNC(=O)C(N)CCCCN)cc3)[nH]c2n(CCC)c1=O +COC(=O)CCCC=C(c1cc(C#N)c(OC)c(C(=O)OC)c1)c1cc(C#N)c(OC)c(C(=O)OC)c1 +Cc1ccc(NC(=O)c2ccc(C(=O)Nc3ccccc3N)nc2)cc1Nc1ncc(-c2cccnc2)s1 +CC1=C(N2CC(C)C3(CCN(CC(O)c4ccc5c(c4C)COC5=O)CC3)C2=O)COC1=O +Cc1cc2c(cc1C)C(C)(F)C(=O)N2CC1CCC(NC(=O)c2cc(Cl)cnc2C)CC1 +Cc1ccccc1N(CCO)C(=O)Nc1ccc(-c2ncnc3[nH]cc(C)c23)cc1 +COCOC(C(CNC(=O)OC(C)(C)C)c1ccc2c(c1)OCO2)C1OC(C)(C)OC1CO[Si](C)(C)C(C)(C)C +O=C(O)Cn1c(=O)c(CCc2ccc(O)cc2)nc2cccnc21 +Nc1ncc(-c2ccc(C3(c4noc(-c5cnccc5O)n4)CCC3)cn2)cn1 +CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1 +Cc1cn(-c2ccc3n(c2=O)CCN(C(C)C2CCC(c4cc(F)c(Cl)c(F)c4)O2)C3=O)cn1 +C=CCc1cc(OC)c(OC(C)C(OC2CC(C)CCC2C(C)C)c2ccc(O)c(OC)c2)c(OC)c1 +CC(C)(C)OC(=O)N1CCC(c2cc3cc(-c4ccc(S(C)(=O)=O)c(F)c4)ncc3o2)CC1 +NC(C(=O)N1CCSC1)C1CCC(NS(=O)(=O)c2ccc(F)c(F)c2F)CC1 +NS(=O)(=O)c1ccccc1N=C1C(=O)Nc2ccccc21 +NC(CSC1(c2ccc(Cl)cc2)c2ccccc2CCc2ccccc21)C(=O)O +CC(c1ccc(-c2ccn(C)c(=O)c2)cc1)N1CCC2(CCCC(O)C2)OC1=O +CNC(C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)c1nc2ccccc2s1)(c1ccccc1)c1ccccc1 +c1ccc(CN(c2ccc3[nH]ccc3c2)C2CCNC2)cc1 +O=C1CC2(CCN(C(=O)Nc3ccc(OC(F)(F)F)cc3)CC2)Oc2c(F)cccc21 +CC(=O)NC(C(=O)NO)C1CCN(c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1=O +COc1ccccc1C(=O)NCC(NS(=O)(=O)c1c(C)cc(C)cc1C)C(=O)O +C=C(C)C(=O)Nc1cc(C)cc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1 +O=C(CCC(=O)c1ccc(Oc2ccc(Cl)cc2)cc1)NO +COc1cc(-c2cn[nH]c2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 +Cc1cnc(-c2cc(Cl)ccc2F)cc1Nc1ccnc2cn(CC(N)=O)nc12 +CC(C)N1CCC(Oc2ccc(CN3CCC(O)CC3)cc2)CC1 +CC(C)C(CO)NCc1nc(-c2cccc(N3CCCC3)c2)ccc1F +Nc1nnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCS(=O)(=O)CC3)cc2F)s1 +CC(c1ccc(-c2cc(F)cc(F)c2)cc1)C(N)C(=O)N1CCC(F)C1 +Cc1ccc(C#Cc2ccc(SC(CCN3C(=O)c4ccccc4C3=O)C(=O)O)cc2)cc1 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+O=C(NCc1ccc(F)cc1)c1nc(-c2nccs2)nc(O)c1O +CCC1CCCC(C2(OC(=O)N3CC4CCC(C3)N4CCO)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCN(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(OC)cc1 +CCCc1cn(-c2nc(N)c3ncn(C4OC(COS(=O)(=O)NC(=O)c5ccccc5O)C(O)C4O)c3n2)nn1 +CNC(=O)Nc1ccc(O)cc1OCC(O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 +Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O +CCCCS(=O)(=O)NCCCCC(C)C1CCC2C(=CC=C3CC(O)CC(O)C3)CCCC21C +CN(c1ncnc2[nH]ccc12)C1CC(NS(=O)(=O)NCCCC#N)C1 +CN1CCC(N2CNc3ccc(NC(=O)c4ccc(F)cc4Cl)cc32)CC1 +O=C(NC(Cc1ccccc1)C(O)CN1CCCCCCCCCCC(c2ccccc2)OC1=O)OC1COC2OCCC12 +COc1ccc(N(C(=O)c2ccccc2)C2CCN(Cc3ccccc3)CC2)cc1 +CNCCON=Cc1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F +CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(-c3nnc(C)o3)c2)cn1 +O=C(C(=NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)C(F)(F)F)c1ccc(Cl)cc1 +Cc1cccc(-c2nc(NCc3cccc(C(N)=O)c3)sc2-c2ccc3ncnn3c2)n1 +COCC(NC(=O)c1cc(-c2ccccc2)nc2ccccc12)c1ccccc1 +CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(-c4nnc(-c5ccccc5)s4)cc32)c1C +CCCCc1nc(CO)c(Cl)n1Cc1ccc(-n2cccc2C(=O)O)cc1 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+CN(c1ccc(NS(=O)(=O)Cc2ccccc2F)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +O=C(Nc1ccccc1)Nc1ccc(C(=O)NCCN2CCOCC2)cc1 +CCC(=O)NC1CCC(CNC(=O)c2ccccc2OC)(c2ccccc2)CC1 +CNCc1cc(C#CCCN2CCOCC2)ccc1Oc1ccc(Cl)cc1 +COCCn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 +Nc1oc2ccccc2c(=O)c1C=C1COc2ccccc2C1=O +CC1c2cccc(C(N)=O)c2C(=O)N1c1ccc(N2CCOCC2)cc1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(O)cc2)nc2c(Cl)cc(Cl)cn12 +Cc1nc(NS(=O)(=O)c2ccc(-c3ccc(C#N)cc3)cc2)ccc1F +NC1CCCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(F)c(O)c(Cl)c5)nc34)cn2)C1 +O=C1NCCN1c1ccc(S(=O)(=O)Nc2cccc(Cl)c2)cc1 +CCCc1c(C(C)C)nc(C(C)C)c(C(C)O)c1-c1ccccc1O +CCc1nccc2c1c(Sc1ccc(Cl)c(Cl)c1)c1n2CCCC1CC(=O)O +COc1cc(OCc2cccc(-c3ccc(F)cn3)c2)c2cc(-c3cn4nc(C(C)F)sc4n3)oc2c1 +OCC(CO)Nc1ncnc2[nH]cc(-c3ccccc3)c12 +Cc1ccnc(N2CCN(CCCCN3C(=O)CC4(CCCC4)CC3=O)CC2)n1 +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(N)=O)cccc2-3)cc1 +CCNC(=O)c1c(-c2ccccc2)c(-c2ccc(F)cc2)c(CCC(O)CC(O)CC(=O)O)n1C(C)C +Cc1cccc(S(=O)(=O)NCCCN2CCN(c3nsc4ccccc34)CC2)c1 +OCC1CCN(c2nccnc2C2CN(c3ncc4cccc(Cl)c4n3)C2)CC1 +Cc1ccc(Oc2cnc(NC(=O)C(OC3CCOC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)cc1C(=O)O +O=C(NCC(c1ccc(C(F)(F)F)nc1)N1CCC(F)(F)CC1)c1c(F)cccc1Cl +CCC(=O)C1(C)CCC2C3CCC4=CC(=O)CCC4=C3CCC21C +COc1ccc2c(c1)C1(CC1c1ccc3c(C=Cc4ccc(CN5C(C)CN(C)CC5C)cc4)n[nH]c3c1)C(=O)N2 +CN(C(=O)c1ccc(C#Cc2cccc(Cl)c2)cn1)C(C)(C)C +O=C(NO)C(CO)OC(CO)c1ccc(C#CC#Cc2ccccc2)cc1 +CC(C)C1(C(=O)N2CCc3ccc(C(F)(F)F)cc3C2)CCC(NC2CCc3c(C#N)cccc32)C1 +Cc1ccc(S(=O)(=O)n2c(CCCN3C(=O)c4ccccc4C3=O)nc3cc(Cl)c(Cl)cc32)cc1 +N#Cc1ccccc1N1CCN(CCCCN2C(=O)C3CCCN3C2=O)CC1 +COc1c(C)c2c(c(O)c1CC=C(C)C=CP(=O)(O)O)C(=O)OC2 +Cc1c(CN2CCc3c(c(=O)n(CCN(C)CCc4ccccn4)c(=O)n3CC3CCCCC3)C2)sc2ccccc12 +N#Cc1ccc2cc1Oc1ccc(C#Cc3ccccc3)c(c1)CN1CCN(CC1=O)Cc1cncn1C2 +O=[N+]([O-])c1ccc(N2CCNCC2)cc1NCc1ccc(Cl)cc1 +Cc1nc(-c2cnn(C)c2-c2ncc(C(F)(F)F)cc2F)c2c(N3CCC3)ncnn12 +COc1cccc(-c2ccc(OCc3cc(C(=O)O)oc3C)cc2)c1 +O=C(O)c1cc(-c2cccc(O)c2)nc2c1cnn2Cc1ccncc1 +NS(=O)(=O)CC(CC(=O)Nc1ccc(Oc2ccc(Cl)c(Cl)c2)cc1)c1ccccc1 +O=C(CCl)Nc1cc(-c2ccccc2)c(-c2nnc3sc(-c4cccc([N+](=O)[O-])c4)nn23)s1 +COCCNC(=O)c1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 +CN(C(=O)C1CCCN1C(=O)C(NC(=O)C=Cc1ccc(OP(=O)(O)O)cc1)C(C)(C)C)c1ccccc1 +CN1CCN(c2cccc(Nc3nc4c(-c5ccc(N(C)S(C)(=O)=O)cc5)cccn4n3)c2)CC1 +CC(C)Oc1nc(-c2ccccc2OC(F)(F)F)cc2nc(-c3c(Cl)c(C(C)(C)C)nn3C)[nH]c12 +Cc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)ccc1-c1nc(C2CCC3CCC(=O)N3C2)n2ccnc(N)c12 +CN(C)CCCn1nc(C2=C(c3cn(-c4cccs4)c4ccccc34)C(=O)NC2=O)c2ccccc21 +CNCc1cc(Br)cc(OCc2ccc3ccc(N)nc3c2)c1 +C=CCN(CCC)Cc1c(C)nc2n(-c3c(C)cc(C)cc3C)c3ncccc3n12 +CC(Oc1cc(-c2cnn(C(F)F)c2)cc2ncsc12)C1CNC(=O)O1 +CC1(C)Oc2ccc(C#N)cc2C(n2ccccc2=O)C1O +CN1C(CC(=O)c2ccccc2)CCCC1CC(OS(=O)(=O)c1ccccc1)c1ccccc1 +COc1cc(-c2ccc(Cl)cc2C)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 +N=C(N)c1cccc(-n2nc(C(F)(F)F)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2F)c1 +CC1(C)c2cc(C(=O)NCCNS(N)(=O)=O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +O=C(c1cccnc1)C(F)(F)CCCCOc1cccc(OCc2ccccc2)c1 +O=C(Nc1cc2ccc(Oc3ccccc3)cc2cn1)C1CC1 +Cc1ccccc1C1CC2CCC(C1)N2C(=O)C(CCCc1ccccc1)NC(=O)C(C)(C)N +CCOc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(OCCO)cc2n1 +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)cn(C)c2=O)C3=O)c(OC)n1 +CC(C)(C)NCC(O)c1ccc2c(c1)C[OH+][BH](O)(O)O2 +CCCOc1c(OCCCO)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)=O +COc1ccc(-c2cc3c(nn2)c(NCC(=O)N(C)C)nc(=O)n3CCOCC(F)(F)F)cn1 +COc1ccc(C2CCCCC2NC(=O)C(c2ccccc2)c2ccccc2)cc1 +Cc1cccc(O)c1C(=O)N1CCC(C)(N2CCN(C(C)c3ccc(C(F)(F)F)cc3)C(C)C2)CC1 +Cc1ccccc1N1CCN(c2ccc(S(=O)(=O)C3(C(=O)NO)CCOCC3)cc2)CC1 +O=c1[nH]c(=O)n(C2CC(O)C3(CO)CC23)cc1I +Cc1nc(C(C)(C)NC(=O)c2ccc(C3CC3)c(OCC3CCOCC3)n2)no1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2cnn3ccccc23)CC1 +Cn1nc(Cl)c2cn3nc(NCCN4CCN(c5ccccc5Cl)CC4)ccc3c2c1=O +CC12CC(=O)C3C(CCC4CC(O)CCC43C)C1CC(=N)N2 +CC(C)(Cn1c(=O)[nH]c(=Nc2cccc(OC(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O +Cc1ccc(C(=O)Nc2cccc3c(=O)cc(C(=O)O)oc23)cc1 +Cc1ccc(N2C(=O)C(=CNc3ccccc3-c3nnc(S)nc3O)c3ccccc3C2=O)cc1C +CCN(CCCCCC(=O)c1ccc(N2CCCC2)cc1)Cc1ccccc1OC +CNc1nc(Nc2cnn(CCC#N)c2C)ncc1C(F)(F)F +O=C(Nc1ccc(CCC2CCCNC2)cc1)c1ccc(Cl)cc1 +CNCC(O)CCN1c2ccccc2N(c2cc(F)ccc2F)S1(=O)=O +COc1cc(OC)cc(N(Cc2ccc(Cl)s2)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1 +CC1(NC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(Cl)cc3Cl)n(-c3ccccc3)n2)COC1 +Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)Cc4ccccc4Br)cc23)c1 +CC(=O)c1nc(CC(=O)N2C(C(=O)NC(CO)c3cccc(Cl)c3F)CC3CC32)n2ccccc12 +CC(NC(=O)c1ccno1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 +CSc1nc(NC(=O)Cc2ccccc2)n2nc(-c3ccco3)nc2n1 +Cc1ccc(CN2CCC(N3Cc4cccc(C(N)=O)c4C3=O)CC2)cc1C +Cc1csc2nc(C(C)NC(=O)C=Cc3ccc(Br)o3)oc(=O)c12 +CC(C)CC(NC(=O)C(NC(=O)COc1ccc2c(c1)Nc1ccccc1S2)C(C)O)C(=O)NC1CCOC1O +O=C(NC1CCOCC1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CCOC(=O)COc1ccc(Oc2cc(-n3nc(C)n(C(F)F)c3=O)c(F)cc2Cl)cc1 +N#Cc1ccc(-c2nc(NCCNc3ccc([N+](=O)[O-])cn3)ncc2C(=O)NCCN)cc1 +COc1cccc2c(O)nc(-c3ccc(C(F)(F)F)cc3)nc12 +COC(=O)C1C(C=Nc2cncnc2N)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2cc(O)ccc2n1Cc1ccccc1 +Cn1c(=NC=Cc2sc3ccc(Cl)cc3[n+]2C)sc2ccccc21 +CC12CCCN(C(=O)c3ccc4nc[nH]c4c3)C1CCc1ccccc12 +CCN(CC)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3CC(c2ccccc2)c2ccccc2)cc1 +COc1cc2ccccc2cc1C=C1SC(=S)N(CC(=O)O)C1=O +O=C1c2cccc3c([N+](=O)[O-])ccc(c23)C(=O)N1C1CN2CCC1CC2 +CCC(=O)N(c1ccccc1)C1(COC(=O)C(C)(C)C)CCN(CCc2cccs2)CC1 +CCOC(Cc1ccc(OCCN2CC=C(c3ccc(OC)cc3)CC2)cc1)C(=O)O +CCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2C(F)F)CCC3)cc1 +Nc1ccc2c(c1)-c1c(cccc1C(=O)NCCCCN1CCN(c3cccc(Cl)c3Cl)CC1)C2 +COc1ccc(C=Cc2cc3c(c(=O)n(C)c(=O)n3C)n2C)cc1 +O=C(c1ccccc1)n1cc(C=Nc2ccc(C(F)(F)F)cc2)c2ccccc21 +CCCCCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)nn1 +O=C(Nc1ccc2c(c1)OCCO2)c1cc2sccc2n1Cc1ccc(F)cc1 +N#Cc1ncc(F)c(N(CCc2cccc(Br)c2)Cc2ccc3c(c2)OCO3)n1 +CC(=O)c1c(C)nc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1NC1CCC(CN(C)C)CC1 +O=C(C1CSC(c2cccnc2)N1)N1CCN(CCCc2ccccc2)CC1 +CCc1ccc2[nH]nc(C(=O)NCC3CCN(CC(=O)O)CC3)c2c1 +N=C(N)c1cccc(Oc2cc(Br)ccc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +COC(=O)c1ccc(C)c(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)c1 +COc1ccc(C(O)(c2cncnc2)c2ccccc2Cl)cc1 +CCC1C(=O)N(C2CCN(CCCc3ccccc3)CC2)c2ccccc21 +Cc1ccc(N2C(=O)C3C(c4ccccc4)NC4(C(=O)c5ccccc5C4=O)C3C2=O)cc1Cl +O=C(CCCCc1cccs1)Nc1ccc2c(c1)COC(C(=O)O)C2 +CCOC(=O)C1=C(CN2CC(F)(F)CC2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Br +CCCCCCNC(=O)CN1CC(=O)N(C)C(Cc2ccc(-c3cc(OC)c(OC)c(OC)c3)cc2)C1=O +Cc1c2c(cc[n+]1Cc1ccc(F)cc1)c1ccc(OCc3ccccc3)cc1n2Cc1ccccc1 +CN1CCC(n2cc(S(=O)(=O)c3ccccc3)c3cccnc32)C1 +O=C(OC1CC2CCC(C1)N2CCc1ccccc1)c1ccccc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCNC(C)=O)cc3)[nH]c2n(CCC)c1=O +CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(C)(C)C(N)=O)CC3)n(C)c2n1 +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)nc2c(F)cccn12 +CCn1cncc1C(OC)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cc3ccccc3)c1)cc(=O)n2C +CN1CCN(Cc2ccc3c(c2)Cc2c(-c4csc(C#CCNC(=O)Oc5ccccc5)c4)n[nH]c2-3)CC1 +CC(C)CC(NC(=O)c1cc(COc2ccccc2)ccc1CCC(=O)O)c1ccccc1F 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+CN1CCc2ccc(NS(=O)(=O)c3ccc(-c4ccc(C#N)cc4)cc3)cc2CC1 +Cc1ccc2oc(C=Cc3ccc(N(C)C)cc3)cc2c1 +O=C(NCC(O)CN1CCc2ccccc2C1)c1cncc(NC2CCOCC2)c1 +NN(C(=O)c1ccc(Cl)cc1Cl)S(=O)(=O)c1ccc2ccccc2c1 +O=C(NCc1ccc(NS(=O)(=O)C2CCCC2)cc1)c1cc2cnccc2[nH]1 +NC1=NC2(c3ccccc3)CN(c3ncc(F)cn3)CC2CS1 +COc1ccc(OC)c(S(=O)(=O)n2cc(CCN(C)C)c3cccc(OC)c32)c1 +Clc1ccc(Nc2nccc(N3CCN(c4ccnc5cc(Cl)ccc45)CC3)n2)cc1 +CCN(C)C(=N)c1ccc(C(=O)N2CCN(S(=O)(=O)c3cc4ccc(Cl)cc4s3)CC2)cc1 +Nc1nc2ccccc2n2c(=O)n(-c3ccc(Cl)cc3)nc12 +CCOc1ccc(OC)c(C2CC2NC(=O)Nc2ccc(Br)cn2)c1F +Cc1cc(F)cc(-c2[nH]c(CNc3ccccc3)nc2-c2ccc3ncnn3c2)n1 +O=C(N1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)C(O)C1)C1(C(F)(F)F)CC1 +O=C(CC(c1ccccc1)c1ccccc1)N1CCN(Cc2cccnc2)CC1 +O=C(O)C1CN(Cc2ccc(-c3nc4cc(Cc5ccc(Cl)cc5)ccc4s3)c(F)c2)C1 +CC1CC(=O)Nc2cccc(C(=O)Nc3cccc(-c4cnco4)c3)c2N1 +CCCN(CC1CC1)C(=O)c1c(CC)nc2n1CCN2c1c(C)cc(C)cc1C +O=C(COc1ccc(-c2ccccc2)cc1)Cn1nnc2ccccc21 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC(C)(Cc1ccccc1)C(=O)NCCCCCCCNC(N)=O +OC(c1ccc(C(F)(F)F)cc1)(c1cccnc1)c1ccc(Cl)cc1F +COc1cc(F)cc2c1nnc1c(C)nc(-c3cccnc3C)n12 +Cn1cncc1C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O +CC(C)C(NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(C(=O)C2CN(C(C)C)CC2c2cccc(Cl)c2)CC1 +O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ncccn3)cc2)c2ccccc12 +COC(c1ccc(C(F)(F)F)cc1)C1CC1c1cc(C)c(OC(C)(C)C(=O)O)c(C)c1 +N#CC(=CC1CC1)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cccc(F)c3)cc2)c2c(N)ncnc21 +COC(=O)C(C)NP(=O)(OCC1OC(n2cc(F)c(=O)[nH]c2=O)CC1O)Oc1ccccc1 +CC(=O)NC1C(O)C=C(C(=O)O)OC1C(O)C(O)Cn1cc(CO)nn1 +N#Cc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)NC(CCO)c3ccccc3)cc1)C2 +CCOC(=O)CCS(=O)(=O)c1nc(-c2ccccc2)cc(C(F)(F)F)n1 +O=C1CN(c2cccc(-c3n[nH]c(C4CCCCN4C(=O)COc4ccccc4)n3)c2)C(=O)N1 +CCC1(C(=O)Nc2cc(CN3CCOCC3)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)C1C +COC(=O)CC1c2ccccc2N=C(NCCCCCN)N1c1ccc(-c2ccccc2)cc1 +CN1C2CCCC1CC(NC(=O)c1cccc3oc(N4CCOCC4)nc13)C2 +CC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cn3nc(C(F)F)c(Cl)c3C)C2SC1 +COc1ccc(C(=O)C(Cc2ccccc2)=C(C(=O)O)c2cc(OC)cc(OC)c2)cc1 +COC(=O)C(=O)OC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +CC1(C)c2cc(Oc3ncccn3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +O=C(NCCO)C1=Cc2c(ncnc2Nc2ccc(Oc3cccc4sccc34)c(Cl)c2)NCC1 +COc1c(C(=N)N)cccc1-c1cc(-c2ccc(C(=N)N)cc2[N+](=O)[O-])no1 +CCC(=O)NC1CC(n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(NCCc4cn(CC)cn4)nc32)C(O)C1O +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCCc1scnc1C)CC2 +CC(C)C#CC1(C(F)(F)F)NC(=O)Nc2ccc(F)c(F)c21 +COc1ccc(C2CC(c3ccccc3)=NN2C(N)=O)cc1 +O=C(Nc1nc2c(s1)COc1ccccc1-2)c1ccc(Nc2ccncn2)cc1 +O=C1CC(O)CC(C=Cc2c(Cl)cc(Cl)cc2OCc2ccc(F)cc2F)O1 +NC(=O)c1cc(-c2ccc(OCCN3CCCOCC3)c(Cl)c2)nc2c1[nH]c1cc(N3CCOCC3)ccc12 +O=C(NCCCCCCCNc1c2c(nc3ccccc13)CCCC2)c1cc2cc(OC(F)(F)F)ccc2oc1=O +CNC(=O)c1c(C(N)=O)nc2n1CCOc1cc(F)c(C#CC(C)(O)c3ccccn3)cc1-2 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC(C)N(S(C)(=O)=O)CC3)cc12 +CN(C)c1ccc(C(=O)N2CCCN(C(=O)Nc3ccc(C(C)(C)C)cc3)CC2)cc1 +O=C1OC2(CCC(N3CCC(Cc4ccccc4Br)CC3)CC2)c2ccc3c(c21)OCCO3 +COc1ccc(-c2ccc(C(=O)N3CCc4cc(OC)c(OC)cc4C3)o2)cc1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1C2CCC1c1nnc(-c3ccc[nH]3)n1C2 +CCCC(C(N)=O)C(CC(C)C)C(=O)NC1CCCCN(Cc2cccc(-c3ccc(F)c(Cl)c3)c2)C1=O +COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(=O)C(C)(C)C)cc1 +N#CCc1cc(-c2ccc(Cl)cc2)n(-c2ccc(S(N)(=O)=O)cc2)n1 +CCC(C)C(NC(=O)C(S)Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)O +COc1cc(Cl)ccc1-c1ccnc2[nH]c(C3CNC(C)(C)CO3)cc12 +COc1ccc(Cc2cc(C3CCN(C(=O)c4ccc5c(c4)OCO5)CC3)ncn2)cc1 +COC(C)(C)c1cnc2n1CC(c1cccc(F)c1F)CCC2NC(=O)N1CCC2(CC1)OC(=O)Nc1ncccc12 +Cc1cc(C)c(S(=O)(=O)NC(C)COc2cccc3c2cnn3-c2ccc(F)cc2)c(C)c1 +Cc1ccc(-c2ccc(S(=O)(=O)C(CCN3C(=O)c4ccccc4C3=O)C(=O)O)cc2)cc1 +c1ccc(-c2nc(OCCCN3CCCC3)cc(C3CC3)n2)cc1 +COCCN(C)S(=O)(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C3CC3)n2)cc1 +CC1(F)OC(n2cc(F)c(=O)[nH]c2=O)C(O)C1O +COC1CCC2(C=C(c3cc(-c4ccc(Cl)cc4)ccc3C)C(=O)N2)CC1 +CC1CCC(COc2ccc(F)cn2)CN1C(=O)c1cccc2cc[nH]c12 +CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)c1cnccn1)B(O)O +CC(O)C(NC(=O)N1CCC(c2ccc(-c3ccccc3)cc2)CC1)C(=O)NO +Cc1ccc2[nH]nc(C)c2c1-c1nc2c(c(N3CCC4OCC4(C)C3)n1)CN(c1c(Cl)c(C3CC3)nn1C)CC2 +Cc1cn(-c2ccc(C(N)=O)c(NC(C)(C)C)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c12 +COc1cc2cc(CO)c(CO)c(-c3ccnc(-n4c(=O)ccc5ccccc54)c3)c2cc1OC +CC(CC(=O)O)NC(=O)N1CCC2(CC1)CCN(c1ccc(C(=N)N)cc1)C2=O +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C(C)C)co1 +CCOP1(=O)N=C(C2=C(O)C(C(C)(C)C)N(CCC(C)(C)C)C2=O)Nc2ccccc21 +NS(=O)(=O)c1ccccc1NC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4c[nH]c(=O)cn4)ccn23)c1 +Cc1cc(OCc2c(-c3ccc(Cl)cc3)noc2C(F)(F)F)c(F)cc1CCC(=O)O +Cc1c(-c2nnnn2C2CCCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Br)cc1 +COCc1ccccc1C1C(C(=O)c2cccnc2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +Cc1nc2nc(C(=O)NCc3ccco3)cn2c(-c2ccc(Cl)cc2Cl)c1CN +COC(=O)c1cnc(N2CCN(c3nnc(C(=O)c4ccccc4)c(C)c3C)CC2C)cn1 +O=C(NC1C2CN(Cc3cccs3)CC21)C(O)(c1ccccc1)C1CCCC1 +CN1CCN(CC(=O)OC2CC3(N4CCCCC4)CC(c4ccccc4)C2C(c2ccccc2)C3)CC1 +CC(=O)N1CCN(c2ccc(Cl)c(C3CC(=O)C(Sc4ccccc4Cl)=C(O)C3)c2Cl)CC1 +COCC(C)Oc1nc(Nc2ccc(S(C)(=O)=O)cc2)ncc1C(F)(F)F +O=C(NCc1ccc(-c2cc[nH]c(=O)c2)cc1)c1cccc(F)c1Cl +OCC(O)COc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +N#Cc1ccccc1-c1cc(-c2ccsc2)cn(-c2ccccc2)c1=O +COc1ccc(C2=NN(C(N)=S)C(c3cccc4ccccc34)C2)cc1 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2o1 +O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2ccccc2O)CC1 +O=C(c1ccco1)N1CCCCC1c1nnn(-c2cccc(Cl)c2)n1 +N=C(N)c1cccc(Oc2ccc(Cl)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +CC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCCC2C(O)c1ccc(Oc2ccccc2)cc1 +COc1cc(OC)nc(OC(C(=O)O)C(OC)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)n1 +O=C1C=CC2(CC(c3coc([N+](=O)[O-])c3)OC(c3coc([N+](=O)[O-])c3)O2)O1 +COc1cc(F)ccc1-c1nncc2cc(S(=O)(=O)Nc3nccs3)ccc12 +CCCCN1c2cccc(Cl)c2CN(CC(=O)NO)S1(=O)=O +Fc1cccc(F)c1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc21 +COCC(C1CC1)n1cc(Cl)nc(Nc2cc(C)c(OCF)cc2C)c1=O +CC(C)(NC(=O)c1cc2c(NC(=O)c3ccc(CN4CCCCC4)cc3)n[nH]c2s1)c1ccccc1 +NS(=O)(=O)OCC1CC(Nc2ncnc3[nH]c(-c4cccc5ccccc45)nc23)CC1O +Cc1ccc2c(c1)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C(F)(F)F)nc1N2 +COc1ccc(C(=O)Nc2ncc(-c3ccc(C(=O)O)cc3OCc3ccccc3C#N)s2)cc1 +COc1cc2ccccc2nc1COc1ccc(-c2nn(C)cc2-c2ccncc2)cc1 +Cc1n[nH]cc1C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(C)(=O)=O)C3)c1-c1ccc(F)cc1 +CC1CN(C)CCC1c1cc2c(cc1-c1cccc(F)c1)OCC1=NNC(=O)C(C)N12 +Cc1ccccc1C1CCc2cc(Oc3ncc(C(=O)NCc4ccnc(Cl)c4)s3)ccc2O1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=NC#N)SC2CCCC2)CC1 +CCCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)C1 +OCC1OC(n2cnc3c(NC4CCCCC4)ncnc32)C(O)C1O +CC(C)CC(NC(=O)C1CCCC1C(=O)c1ccc(CNc2nccs2)cc1)C(=O)NC1CCCCC1c1ccccc1 +CC(=O)c1ccc(-c2ccc(C(=O)C(F)(F)F)s2)cc1 +O=c1oc2ccccc2n1CCCCCCN1CCN(c2ccccc2)CC1 +C#CCN1CCc2c(C)c3c(n2-c2cc(Cl)c(C(N)=O)cc21)CC(C)(C)CC3=O +O=C(OC1C[N+]2(Cc3nc4ccccc4o3)CCC1CC2)C1(C2=CC=CC2)CCCCCC1 +COc1ccc(NC(C)=O)cc1C1CN(c2nc(-c3ccncc3F)cc(=O)n2C)CCO1 +Cn1c(=O)n(-c2cccc(C(F)(F)F)c2)c2c3cc(-c4ccc(S(C)(=O)=O)cc4)ccc3ncc21 +Cc1ccc2c(c1)C1(NC(=O)NC1=O)N(C)C(=O)N2 +COCC(C1CC1)n1cc(Cl)nc(Nc2c(C)nc(OC)nc2OC)c1=O +O=C(Nc1ccc(F)cc1F)c1cc2nc3c(c(C(F)(F)F)n2n1)CCCC3 +CC(O)(c1ccccc1)c1ccnc(Nc2ccc(C#N)cc2)n1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)Cc1ccccn1)C2 +C#Cc1ccc2nc(-n3ccnc3)nc(NCc3ccccc3)c2c1 +CC(=O)Nc1cccc(-c2cc(N3CC(N)C(c4cc(F)c(F)cc4F)C3)ncn2)c1 +CN(CCCCN1C(=O)COc2ccccc21)Cc1ccc(Cl)cc1 +Cc1cncn1CCCNC(=C[N+](=O)[O-])NC1CCCCC1 +S=c1oc(-c2ccc3ccccc3n2)nn1CNc1ccc(Cl)cc1 +CC(C)S(=O)(=O)c1cc(-c2ccc(CCNCC(O)c3ccccc3)cc2)ccc1C(=O)O +O=Cc1ccccc1OCc1cn(Cc2ccc3c(c2)C(=O)c2ccccc2C3=O)nn1 +CC(C)(O)Cc1cn2c(N3CCN(C(=O)CCS(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)cccc2n1 +Cc1ccc(OCc2ccc3c(c2)CCN(C2CCOCC2)C3)c(-c2csc(N3CC4CC4(C(=O)O)C3C)n2)c1 +CCOP(=O)(CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)OCC +CC(NC(=O)CC(N)=O)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 +Oc1nc(NCCCNCc2cc(Br)cc(Br)c2)nc2ccccc12 +CN(Cc1c(C(=O)NC2CCCC(O)C2)noc1-c1ccc(C(F)(F)F)cc1)C1CCOC1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1nc2cc(N3CCCC3)ncc2[nH]1 +CCCCCCCN(CC)CCCCc1ccc([N+](=O)[O-])cc1 +COC12C(=O)CCC1(CO)C2C1(C)OC1CC=C(C)C +Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NC(C)C)cn1 +CCOc1c(Br)cc(Cl)cc1CNCCCNc1nc2ccccc2[nH]1 +Cc1ccc(-c2nnc(-c3ccc(C(=O)C(F)(F)F)s3)o2)cc1 +Cc1nc(N)ccc1CNC(=O)Cn1c(C)cc2c(c1=O)NC(=O)CC2 +O=C(CCCCCNC(=O)NC(=O)c1c(Cl)cccc1Cl)NO +CC(=O)Nc1cc(-c2nnc(SCc3cccc(C#N)c3)o2)ccn1 +CC(C)CN(Cc1ccc(N2CCN(C(=O)CC#N)CC2)cc1)S(=O)(=O)Cc1ccccc1 +COc1c(OCCCCN2CCNCC2)cc(O)c2c(=O)cc(-c3ccccc3)oc12 +Fc1ccc(-n2c3c(c4cc(F)ccc42)CN(CCc2cnccn2)CC3)cc1 +O=C(c1cccc(Cl)c1)N1CCC(CNCc2cccc(-n3cccn3)n2)CC1 +Cc1cc(S(=O)(=O)N2CCC(F)(F)CC2)cnc1-c1ccc2c(c1)CCC(C)N2C(=O)c1ccc(O)cc1O +O=C1N=C(O)SC1=Cc1ccc(OCCc2ccccn2)cc1 +Nc1cc(C(F)(F)F)c(-c2cc(Nc3cnc4ccccc4c3)nc(N3CCOCC3)n2)cn1 +O=C(NCCNc1ccnc2cc(Cl)ccc12)Nc1ccc(Cl)cc1 +O=S(=O)(Nc1cscn1)c1cc(Cl)c(OCC2NCCC=C2c2ccc(F)c(F)c2)cc1F +O=c1[nH]c(=O)n(COC(CO)CO)cc1Cc1cccc(Oc2ccc(F)cc2)c1 +CC1CN2c3c(cc4c(N5C(=O)OCC5CCCO)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ncc(C(C)CC(C)(C)C)s1 +Cc1c(C(O)CN2CCC3(CC2)CCN(c2cn(C)c(=O)cn2)C3=O)ccc2c1COC2=O +CCN(CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1)C(=O)c1ccc2nc(N(C)CC)oc2c1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCCCC3)c3ccccc23)cc1 +CC1(C)C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4cc(Cl)ccc34)nnc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(Cc2cccnc2)CC1 +Cc1nc(-c2ccc(Cl)cc2)sc1C=CC1CCCN(c2cccc(C(=O)O)c2)C1 +CC(CN(C)C)NC(=O)c1c(F)cc(-c2noc(C(F)(F)F)n2)cc1F +CC(CCc1ccc(-c2cccc(C(N)=O)c2)cc1)(C(=O)NO)S(C)(=O)=O +CNCC(O)C(c1cccc(F)c1)N1CC(C)(C)c2cccc(F)c21 +OCCOCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)nc(O)c21 +CN(C)CCn1cc(-c2ccncc2)cc(NC(=O)C(Cc2ccccc2)NC2(c3ccccn3)CC2)c1=O +CCCc1cc2c(=O)c(-c3ccc4c(c3)OCCO4)coc2cc1OS(C)(=O)=O +CC(NCc1cc2ccccc2[nH]1)c1ccc(F)c2ccccc12 +CCC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 +CC(=O)Cn1nc(CNC2CCC(F)C2)c(C)c1-c1cc(F)cc(F)c1 +CCC12CCC(=O)C=C1c1c(cc(OCC(=O)OC)c(Cl)c1Cl)C2 +CC(Nc1cc(-c2sc(C3(O)CCN(C)CC3)nc2-c2ccc(F)cc2)ccn1)c1ccccc1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(C(C)CN(C)CCc3ccccn3)c2=O)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC(C)(C)O)c3)C2)cc1 +COc1cc(CC(=O)O)cc(OC)c1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +CC(c1cccc(O)c1)n1cnc2c(N(C)C)ncnc21 +CCCC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3cccc(C)c3)c3ccccc23)CC1 +OCC1OC(c2cc(Cc3ccc(OC4CCOC4)cc3)c(Cl)s2)C(O)C(O)C1O +COc1cc(NC(=O)NOCCCCCC(=O)NO)c2ncccc2c1 +CCOC(=O)c1cc2c(n1CC)C(=O)C(Oc1ccc(Cl)cc1)=CC2=O +CCC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1NC1CCC(CN(C)C)CC1 +CC1(C)c2cc(-c3nc4c(C(N)=O)cccc4[nH]3)sc2C(C)(C)N1O +COC(=O)C12OCC34C(CC5C(C)C(=O)C(O)CC5(C)C3C(O)C1O)OC(=O)C(OC(=O)C=C(C)C)C24 +O=C(C=CCNC12CC3CC(CC(C3)C1)C2)N1CCc2c(sc3ncnc(Nc4ccc(Cl)c(Cl)c4)c23)C1 +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)cc1)Nc1cc(C(F)(F)F)ccc1Cl +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3)cc2n(C)c1=O +O=C(Cc1ccc(Cl)c(Cl)c1)Nc1nc2ccc(OC(F)(F)F)cc2s1 +CNc1nc(Nc2ccc(-c3cn(C)nc3C)cc2OC)ncc1C(F)(F)F +Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)c(F)c3)cc12 +CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(CN3CCOCC3)n1CCO2)CF +CC(C)n1cnc2c(Nc3cncnc3)nc(C(C)(C)CO)nc21 +CC1(C)C=C(c2ccccc2)Nc2c(C(=O)NC34CC5CC(CC(C5)C3)C4)cnn21 +CC(C)Oc1ccccc1N1CCN(CCCCn2ncc(N3CCN(CC4COc5ccccc5O4)CC3)c(Cl)c2=O)CC1 +CCS(=O)(=O)NC(=O)c1c(-c2ccc[nH]c2=O)c2c3occc3ccc2n1Cc1cc(F)ccc1F +NC(Cc1ccccc1)C(=O)NC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +NS(=O)(=O)c1ccc(COC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)cc1 +CC1CN(Cc2ccc(N(C)C(=O)c3ccc(Oc4cccc(F)c4)cn3)cc2)CCN1 +NC1=NC(c2ccccc2)N(c2ccc(Cl)cc2)C(N)=N1 +CC(C)(CN1CCCC1)n1cnc(NC(=O)C(NC(=O)Cc2cc(F)cc(F)c2)c2ccccc2)c1 +O=C(C=Cc1ccc(Sc2cccc(OC3CCSCC3)c2)c(C(F)(F)F)c1C(F)(F)F)N1CCOCC1 +CCCN(CCC)c1c(CC)c(Nc2ccc(OC)cc2Cl)nc2ccnn12 +CS(=O)(=O)Nc1ccc(Nc2ccc3[nH]nc(N)c3c2)cc1 +CC(C)CC(NC(=O)C(CS)C(C)c1ccccc1)C(=O)O +CCn1nccc1NC(=O)c1ccc(C)c(Nc2nc(N)nc(NC(C)C)c2C#N)c1 +COc1cc(C#CCN(C)C)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2C(=O)N(C)C3)n1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccc(OCCC(F)(F)F)cc2)c1 +Cc1cc(Nc2n[nH]c3ncc(F)cc23)nc(C2CCCCCC2)n1 +C[N+](C)(C)CC1COC(C(c2ccccc2)c2ccccc2)O1 +O=C(C=Cc1cccc2c1N(Cc1ccc3ccccc3c1)C(=O)C2(CO)CO)NS(=O)(=O)c1ccc(F)c(F)c1 +CC(NC(=O)C(CS)C(C)c1ccc2c(c1)OCO2)C(=O)O +NS(=O)(=O)c1ccc(NC(S)=NCCC(=O)O)cc1 +COc1cc(N2CCN(C(=O)Cn3nc(CN)c(Cl)c3C)CC2)ccc1Cl +COc1cc(C(N)=O)c2ncnc(NCc3cccc(C(F)(F)F)c3)c2c1 +COc1cc(OC)cc(C(=O)NCc2n[nH]c(=S)n2-c2cccc(C(F)(F)F)c2)c1 +Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOCC5)cc4n3Cc3ccc(F)cn3)cn12 +Clc1ccc(Cn2cc(-c3ccc4[nH]ncc4c3)nn2)cc1 +Cc1ccc(C(c2ccccc2Cl)N2C3CCC2CC(O)(c2cccc(F)c2)C3)c(Cl)c1 +CCCCC(=O)Oc1cccc2c1-c1cc(OC)cc3c1C(C2)N(C)CC3 +COc1ccc(-c2cccc(-c3c(C)cnc4c(C(F)(F)F)cccc34)c2)cc1S(C)(=O)=O +CCCn1c(=O)c2nc(-c3cnn(Cc4cc(-c5ccccc5Cl)on4)c3)[nH]c2n(CCC)c1=O +CCS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CCCN1CCN(C(C)=O)CC1)CCCC3)C(=O)N2 +CC(CNc1ccc(-c2ocnc2C(=O)O)cc1)NCC(O)c1cccc(Cl)c1 +CSc1nc(Nc2ccccc2)c2cnn(CC(C)c3ccccc3)c2n1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3cccc(C4CCN(CC(=O)N(C)C)CC4)c3)nc12 +CC1CCCN1C1CCC(c2ccc(NC(=O)c3ccc(F)cc3)cc2)C1 +Nc1ncnc2c1nc(Sc1cc3ccoc3cc1Br)n2CCC1CCN(C=O)CC1 +O=C(Nc1ccccc1)N1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 +O=C(NCc1cccc(Cn2cccc2C(=O)O)c1)NC12CC3CC(CC(C3)C1)C2 +O=C(O)CCCN1CC(C(=O)O)Oc2c(NC(=O)c3ccc(OCCCc4ccccc4)cc3)cccc21 +CC(C)(C)c1ncc(Cc2cn(CC(=O)N3CCN(c4ccc(Cl)cc4)CC3)c(SCc3ccc(F)cc3)nc2=O)cn1 +Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC2CCCCC2)c2sccc23)cc1C +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3cc(Cl)c(OC(F)F)cc3C)ncnc21 +NS(=O)(=O)c1cc2c(s1)S(=O)(=O)C(CCN1CCOCC1)CN2 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCOCCOC(=O)CC(=O)OCC +O=C(CN1CC(CNS(=O)(=O)c2ccccc2)=CCC(NC(=O)c2ccc3ccccc3c2)C1=O)NC1CC(=O)OC1O +CCCCc1nnc(SCC2CCCCC2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +CCn1c(=O)c2nc(-c3ccc(Cl)cc3N)[nH]c2n(CC)c1=O +CCC(C)N1C(=O)C(NC(=O)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)N=C(C2CC2)c2ccccc21 +CCCn1c(=O)c2nc(C3CCC(=O)C3)[nH]c2n(CCC)c1=O +Fc1ccc(-[n+]2nc(-c3ccccc3)nn2-c2ccccc2)cc1 +CCCC1c2ccccc2C=NN1C(=O)C=Cc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC +CC(=O)Nc1nc2c(Oc3cc(N4CCN(C(C)c5ccc(C(F)(F)F)cc5)CC4)ncn3)cccc2s1 +O=c1c(Oc2ccc3c(c2)CCC3)c(Cl)cnn1Cc1cccc2ccccc12 +Nc1ncnc(N2CCC(c3nc(-c4ccc(F)c(C(F)(F)F)c4)cn3CCN3CCCC3)CC2)c1-c1ccccc1F +CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)N(C)C(Cc1ccccc1)NC(=O)CNC(=O)C(C)c1ccccc1 +CCS(=O)(=O)c1ccc(Oc2ccc(C#N)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +COc1ccc(C(=O)N2CCCC(c3cc(C)nc4ncnn34)C2)cc1C +CCCCCOc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1 +COc1ccc(OC)c(Cc2cc3c(Nc4cccc(Br)c4)nc(N)nc3[nH]2)c1 +O=C(NC1CCCN(Cc2cccc3ccccc23)C1)N1CCc2[nH]nc(-c3ccc4nccn4c3)c2C1 +CC(=O)C1CCC2C3CCC4CC(O)C(N5CCSC(C)(C)C5)CC4(C)C3CCC12C +CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1[N+](=O)[O-] +CC1OC(=O)C2CC3CCC(O)CC3C(C=Cc3ccc(-c4cccc(C(F)(F)F)c4)cn3)C12 +N#Cc1cc(Cl)cc(Oc2cc(OCc3noc4ncccc34)ccc2Cl)c1 +O=S(=O)(Nc1ccc(F)cn1)c1cc(Cl)c(Oc2ccc(Cl)cc2C2CCNCC2)cc1F +COc1ccc(COc2nccc(-c3ccc4nc(NC(C)=O)sc4c3)n2)cc1 +Cn1c(COc2cccc(C#N)c2)nc(N2CCNCC2)cc1=O +CCc1cccc(NC(=O)Nc2ccc(Oc3ccc4nc(NC(=O)OC)[nH]c4c3)cc2)c1 +Cc1c(C(=O)O)oc2cccc(OCc3ccc4nsnc4c3)c12 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cc(N3CCOCC3)ncc2[nH]1)C(F)(F)F +O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(F)c(-c2ccncc2)c1 +COCCOCC(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1 +NC1CC(c2ccncc2NC(=O)c2ccc(F)c(-c3ccccc3F)n2)CCC1O +COc1ccccc1C1CCC(N2CCN(c3ccccn3)CC2)CC1 +CN1C(=O)N(c2ccc(C#Cc3ccccc3)cn2)CC12CC2 +Nc1c2c(cc3c1C(c1ccc(Cl)cc1)c1c(-c4ccccc4)n[nH]c1O3)CCCC2 +Cn1c(=O)c(Cc2ccc(C(=N)N)cc2)nc2cc(C3(N(C(=O)CC(=O)O)C4CCCC4)CC3)ccc21 +N#Cc1cccc(-c2nc(N)c3cc(CN4CCSCC4)sc3n2)c1 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(OCCCCN(C)C)cc2)nc1 +Cn1cccc(Nc2n[nH]c3ccnc(OC4CCOCC4)c23)c1=O +COc1cc(-c2cnc(C)n2C)ccc1Nc1ncc2cc(C)nc(NCC(C)(C)OC)c2n1 +CC1C(NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccc(-c2ccccc2)cc1 +CC(C)CCN1C(=O)C(C2=NS(=O)(=O)c3ccccc3N2)=C(O)C1C(C)(C)C +COc1cc2c(cc1O)-c1n[nH]c(-c3ccc(-c4ccc(O)cc4)cc3)c1C2 +COc1ccc(Cl)cc1-c1nc(N)cc(Nc2ccc(Br)cc2)n1 +O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(C4CCCCO4)cc3)c(F)c12 +CCC(=O)N1CC(C(=O)N2CCN(c3ccc(C)cc3C(N)C(C)C)CC2)C(c2ccc(Cl)cc2)C1 +Cc1nc(-c2ccccn2)nc(NCC(NCCCCN2CCN(CCO)CC2)c2ccccc2)c1Cl +CC(Oc1cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F 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+O=C(CCCN1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)Nc1ccc(Cl)cc1Cl +NC(Cc1cc(F)c(F)cc1F)C1CCN(C(=O)c2cnc3ncccn23)CC1 +CNC(=O)C(NC(=O)c1ccc(-c2ccc(NC(=O)c3cc4ccccc4o3)cc2)o1)C1CCCCC1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1ccc(CN2CCOCC2)cc1 +O=C(c1ccccc1-n1nccn1)N1C2CCC1C(COc1ccc(F)cn1)C2 +N=C(N)SCc1cccc2c1=c1c(CSC(=N)N)cccc1=2 +Cc1cc(C#Cc2cn(C3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)ccn1 +Fc1ccc(C=CCN2CCC(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +CCCCCCCCC=CCCCCCCCC(=O)c1nc2ncccc2o1 +O=C(Nc1cccc(-c2cnc(-c3c[nH]c4cc(F)ccc34)[nH]2)c1)c1cccnc1 +Cc1noc(-c2sc(NC(=O)c3ccccc3)nc2-c2ccccc2)n1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCn3ccnc3)c3ccccc23)cc1 +Nc1ncnc2nc(-c3ccc(N4CCC(O)(C5CCOC5=O)CC4)nc3)cc(-c3cccc(Br)c3)c12 +[C-]#[N+]C1(C)C(C)CC2CC(C)C3CCC(C)(N=C=S)C4CCC1C2C34 +COc1ncc(Cl)cc1-c1ccc2cc(C(=O)c3cnn(-c4ccc5[nH]c(C)nc5c4)c3N)[nH]c2c1 +O=C(Nc1cnn(S(=O)(=O)c2cc(Cl)ccc2Cl)c1)c1ccccn1 +O=C(OCc1ccccc1)N1CCCC1c1cc(-c2ccncc2)c(-c2ccc(F)cc2)[nH]1 +Nc1nc2c(cnn2CCN2CCN(c3ccccc3F)CC2)c2nc(-c3ccco3)nn12 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+N#CCCNC(N)=NC(=O)Cn1c(-c2ccccc2)ccc1C12CC3CC(CC(C3)C1)C2 +CCCN1CCN(c2cc(-c3ccc(Sc4ccc5c(c4)OCCO5)c(C(F)(F)F)c3)ccn2)CC1 +CC(C)(C)c1cc(Br)ccc1N1CCN(C(=O)CC(=O)O)CC1 +O=c1c(Cl)c(N2CCCCC2)cnn1-c1nc2ccccc2[nH]1 +CCCCc1ccc(Nc2nc(C(C)(C)C(=O)O)cs2)cc1 +Cc1ccc(-c2cc(C#N)ccc2COCc2cncn2Cc2ccc(C#N)cc2)cc1C +CN(C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccnc(N)c2)CC1 +COc1cc2c(Nc3ncc(CC(=O)Nc4cccc(F)c4F)s3)ncnc2cc1OCCCN1CCCC1CO +COc1ccc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +O=[N+]([O-])c1cc(C(F)(F)F)cc([N+](=O)[O-])c1Oc1ccccc1C=NOCc1ccc(Cl)cc1Cl +CC1CCN(CCOc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)CC1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCc1nnn[nH]1 +COc1cc(COc2c(C)cccc2-c2csc(N3CCC(C(=O)O)C(OC)C3)n2)cc2c1CN(C1CCOCC1)CC2 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NC(=O)Cc1cc(N)ccc1-2 +C=CS(=O)(=O)Nc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1 +COc1cc2oc(=O)cc(-c3ccccc3)c2cc1OC(=O)Cc1cccs1 +CCN(C(=O)C1=CCCC1C(=O)NCc1ccc(C(=N)N)cc1)C1CCCCC1 +C=CC(=O)Nc1cccc(Nc2nc(NN=Cc3ccc(F)cc3)ncc2Cl)c1 +CCCCCCCN(CCOCCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)[nH]1)C(=O)NC(C)C +CNC(=O)c1cc2c(Oc3ccc(-c4ccco4)cc3)cncc2s1 +CC(F)(F)c1nc2ccccc2n1Cc1ccc(C(=O)NC2CCOCC2C(=O)NO)cc1 +CCCN(CC1CC1)c1cc(C(O)c2c(CC)cc(CC)cc2CC)nc(C)n1 +CCCCC(C)CC(C)C(=O)N(C)C(CC(C)C)C(=O)NC(C(=O)N(C)C(C(=O)OC)C(C)C)C(C)OO +Fc1cccc(Cl)c1-c1nc2c3cc(Cl)ccc3c3ccccc3c2[nH]1 +O=C(Nc1ccc(F)cc1)Nc1ccc(C=CC(=O)c2ccccc2)cc1 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccc(F)cc2)c1)C(F)(F)F +CNC(=O)c1c(F)cc(F)cc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +CN1C(=O)CCc2cc(-c3cncc4c3CCCC4=O)ccc21 +Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CN(C)C4CCOCC4)cc2)CCC3)cc1 +Cc1cc(C)c2ncc(NC(=O)Nc3ccc(F)cc3F)c(-c3ccccc3Cl)c2c1 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(OC(F)(F)F)c4)c3)cc12 +Cc1nn(Cc2ccc(NC(=O)c3ccc(C(C)(C)C)cc3)cc2)c(C)c1CCC(=O)O +CN(C)Cc1ccc(CSCc2ccc(-c3ccc(CSCc4ccc(CN(C)C)o4)cc3)cc2)o1 +Cc1c2c(n(-c3ccc(Cl)cc3Cl)c1-c1cccc(C(F)(F)F)c1)CCN(C1CCCCC1)C2=O +CC1(C)c2cc(N3CCC(N4CCOCC4)CC3)c(Cl)cc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +COc1cccc(C(=O)Cn2c3c(sc2=N)CCCC3)c1 +O=C(NCCCCCCc1ccccc1)Oc1cccc(N2CCNCC2)c1 +O=C(CNc1ccc(F)cc1)NN=Cc1c(O)ccc2ccccc12 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)cc1-c1cccc(C(F)(F)F)c1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cccc(S(=O)(=O)NCc3ccc(C(=O)O)cc3)c2)c1 +Cc1ccc(-c2ccccc2)c(C(=O)N2CCC2c2nc(-c3ccccc3OC(F)(F)F)no2)c1 +CCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC +Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCN(C)CC2)cc1Cl +NC(=O)OCC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(CC(O)C(F)(F)F)c1=O)c1ccccc1C(F)(F)F +Cn1c(CN2CCN(c3ccccc3C(F)(F)F)CC2)nc2ccccc21 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4CCOC4C3)n2)cc1C(F)(F)F +Cc1noc(C)c1-c1ccc2c(c1)C(c1ccsc1)(N1CCCC(N)C1)C(=O)N2 +CCCN(Cc1ccc(OCCn2c(=O)ccn(C)c2=O)c(C)c1)C(CC(=O)O)c1ccc2c(c1)CCO2 +Cc1cccc2c3c(ccc12)C1=C(C(=O)C3=O)C(C)CO1 +CCN(CC)C1CC(c2ccc(Cl)c(Cl)c2)c2ccc(O)cc21 +CCOC(=O)C(Cc1cc2ccnc(N)c2cc1OC)N1CCC(NS(=O)(=O)c2cnc(N3CCC(F)(F)C3)s2)C1=O +O=C(O)C(C1CCN(C(=O)C=Cc2cc(F)c(F)c(F)c2)CC1)N1CCC(c2c[nH]c3ccccc23)CC1 +COc1cc(I)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)OCCO[Si](C)(C)C(C)(C)C)n1 +NC(=O)N(O)CCON=Cc1ccc(Oc2ccc(F)cc2)o1 +O=C(O)c1ccc(N2CC3(CCN(Cc4cn(-c5ccc(F)cc5)nc4-c4ccc(F)cc4)CC3)OC2=O)cc1 +Cc1cnc2c(c1)C1c3cc(O)c(O)cc3CCC1NC2 +O=C(COc1ccc2[nH]c(-c3ccc(Cl)s3)nc2c1)Nc1ccc(N2CCOCC2=O)cc1 +O=C(NC1c2ccccc2CC1c1ccc(O)cc1)C(c1ccccc1)c1ccccc1 +O=S(=O)(Nc1cc(-c2cccs2)nn1-c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ccc(S(=O)(=O)NC2CCC(CCN3CCC(c4coc5ccccc45)CC3)CC2)cc1 +Cc1cc(OCCCN2CCCC2C)ccc1C(=O)CN1CCOCC1 +Cc1nc(Nc2ccc(F)c(Cl)c2)c2cc(NC(=O)CCN(C)C)ccc2n1 +CC1=C(C=CC#Cc2ccc(C(=O)O)cc2)C(C)(C)CCC1 +CN(C)C(=O)C1Cc2ccccc2N1C(=O)CCN1CCN(c2ccccc2)CC1 +Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)Nc1ccc(NC(=O)CCCCC3CCSS3)cc1)O2 +O=C(Nc1ccc(CC2CCC(C(O)c3cccnc3)N2)cc1)C1CCc2sc(C3CC3)nc21 +CC(NC(=O)c1c(C(F)F)nn(C)c1Oc1cccc(C(F)(F)F)c1)c1ccc(C(=O)O)cc1 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccc(Br)cc3)CC2)n1 +COc1cc(OCc2cccc(OCc3ccc(F)c(C(F)(F)F)c3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CC1(C)CN(Cc2ccccc2)C(=O)C1Oc1ccc(C#N)c(C(F)(F)F)c1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1C)CC2 +COc1cc(OC)cc(Oc2ccncc2-c2n[nH]c(Nc3ccc4c(c3)OCCO4)n2)c1 +CN1CCN(CCCN(c2nc3cc(Cl)c(Cl)cc3[nH]2)C2CCC3(c4cccc(C#N)c4)CC23)CC1 +Cc1ccnc(NCC2CCN(c3ccc(CC(NC(=O)C4(C)CCCCC4)C(=O)O)cc3)CC2)c1 +Cc1cc(CNc2c(C)ccc(OCC(=O)O)c2C)cc(-c2cccc(F)c2)c1 +O=C(NCc1ccccc1)NC1CC2CCCC(C1)N2Cc1ccccc1 +COc1ccc(C2=NN(Cc3ccccc3)C(=O)C3CCCCC23)cc1OC +CC(=O)C1CCC2(C(=O)O)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +Cc1cn(C2CCCN(S(=O)(=O)c3ccc(C(N)=O)c(Oc4cccc(Cl)c4)c3)C2)c(=O)[nH]c1=O +COc1cc(F)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C(NC1CCCCC1)N1CCN(C(c2ccc(Br)cc2)c2ccccc2Cl)CC1 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(O)C5)cn3)n2)s1 +CC(Oc1cc(-n2cnc3cc(-c4cnn(CCN5CCN(C)CC5)c4)ccc32)sc1C(N)=O)c1ccccc1Cl +CC(C)n1cnc2c(NC(=N)N)nc(NCCCO)nc21 +CC(CCc1ccc(-c2ccc3c(c2)CNC3=O)cc1)(C(=O)NO)S(C)(=O)=O +CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCN(C)CC4)nc3)c2n1 +Cn1cc2c(nc(NCc3ccc(C(F)(F)F)cc3)n3nc(-c4ccco4)nc23)n1 +O=C(Nc1ccccc1N1CCNCC1)c1csc(C#Cc2ccccc2)n1 +Cc1nc2ccccc2c(=O)n1CCCCCN1CCN(c2ccc(Cl)cc2)CC1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C(C)CC)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(C#N)cn3)CC2)CC1c1ccc(Cl)c(F)c1 +CC(NC(=O)C(NC(=O)c1ccc2ccccc2c1)C(C)C)C(=O)NC(CC(=O)O)C(=O)COc1ccccc1 +Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc(CNS(C)(=O)=O)cc2)c1 +CCOC(=O)C1=C(C)OC2OC(COCc3ccccc3)C(OCc3ccccc3)C(OCc3ccccc3)C2[S+]1[O-] +O=C(O)c1cccc(S(=O)(=O)Nc2ccc3ccccc3c2)c1 +COc1ncnc(Cn2cc(C(=O)NCC(C)F)c3ncc(C)cc32)c1C +COc1ccc(O)c(C(=O)CC(=O)c2ccc(F)cc2)c1 +COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1noc(C)c1C +CN(c1ncnc2[nH]ccc12)C1CCC(CS(=O)(=O)N2CCC(Cc3cnccn3)C2)CC1 +COc1ccc(NC(=O)N2N=C(c3ccc(Br)cc3)CC2c2ccc(F)cc2)cc1 +CNCCCNc1nc2c(C)cc(C)cc2n1Cc1nc(C)ccc1O +C=CCC(O)C1CCCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C +O=C(NC1CCN(CCO)CC1)c1cc2ccccc2n1Cc1cc(-c2ccc(Cl)s2)on1 +c1ccc(C2(c3ccccc3)CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)cc1 +O=C(NCCC1CCN(C(=O)C=Cc2cc(Cl)cc(Cl)c2)CC1)c1c[nH]c(=O)o1 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+O=C(NCC1(O)COC(CN2C(=O)c3ccccc3C2=O)C1O)c1ccccc1Cl +Cc1cccc(-c2ccc3c(O)oc(=O)c(C(=O)NCC(=O)O)c3c2)c1 +O=c1[nH]c2c(O)ccc(C(O)CNC3CCCC3C3CCCCC3)c2s1 +CC(NC(=O)c1cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CC2)cc2c1CCCO2)c1ccccc1 +Cc1[nH]c(C(=O)NC2CCN(c3ncc(C(=O)O)s3)CC23OCC(C)(C)CO3)c(Cl)c1Cl +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(S(=O)(=O)N3CCOCC3)CC2)cc1 +CC(C)C(=O)N1c2cccc(O)c2NC2=C(C(=O)CC(C)(C)C2)C1c1ccc(OCc2ccccc2)cc1F +COc1cccc(CN(C)C(=O)c2cc3c(Cc4ccccc4)n[nH]c3cc2O)c1 +CCCCCn1cc(C(=O)NN(C)C)c(=O)c2ccc(Sc3ccccc3)cc21 +CCS(=O)(=O)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1C#N +Cc1c2c(n3c1CCN(CCC(C)C)c1cc(C(N)=O)c(Cl)cc1-3)CC(C)(C)CC2=O +OCC(O)CN1C(CCc2cccc3ccccc23)CCCC1CCc1cccc2ccccc12 +CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)ccc2Cl)n1 +CCCCCC#CCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3ccc(Br)cc3)CC2)cc1 +Cc1ccc(-c2nc3cc4c5c(cccc5c3s2)C(=O)N(CCN(C)C)C4=O)cc1 +CC(=O)OCCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 +c1cc(N2CCCN(c3ccc(C4=NCCN4)cc3)CC2)ccc1C1=NCCN1 +COc1ccc(-c2oc3c(OC)c(OC)c(OC)cc3c(=O)c2OC)cc1N +O=C(CCc1ccccc1)c1cc(OCc2ccccc2)ccc1OCC(O)CN1CCN(Cc2ccccc2)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]c(-c4ccc(Br)cc4)nc3c2)c1F +Cc1ccc2cccc(NCc3ccc(C(=O)NO)cc3)c2n1 +CS(=O)(=O)CCCOc1cccc2c1ccn2-c1ccnc(NC2CCC(C(=O)N3CCC(O)CC3)CC2)n1 +COc1cc(C)cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncccn5)ccc43)cc2C)c1 +C=CC(=O)N1CCCC(Oc2nc(Nc3ccc(N4CCC(N5CCN(C)CC5)CC4)cc3)c(C(N)=O)nc2CC)C1 +CCC(CC)OC1C=C(C(=O)Nc2ccccc2)CC(NC(=O)OC(C)(C)C)C1NC(C)=O +C#CCN(Cc1cc2c(O)nc(C)nc2cc1C)c1ccc(C(=O)NC(CCCCC(=O)O)C(=O)O)c(F)c1 +COC(=O)c1c(C(F)(F)F)[n+]([O-])c2ccc(N3CCN(c4ccc(F)cc4)CC3)cc2[n+]1[O-] +COCC(=O)N(Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F)OC +CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)C1CN(C(=O)c2ccncn2)CC1c1ccccc1 +CC(C)c1cc(Oc2c(Br)cc(CCC(=O)O)cc2Br)cc(C=Cc2ccncc2)c1O +CCC=Cc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)O)n2Cc1cc(F)ccc1F +Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCC(C)(C)C3)cc2)c2ccc(O)cc12 +CN1CCN(c2ccc(Nc3cc(-c4nc(NC5CCNC5)c5sccc5n4)ccn3)nc2)CC1 +COC(=O)c1cccc(-c2cc(N3CCN(C(=O)c4ccoc4)CC3)n3nc(-c4cccc(OC)c4)cc3n2)c1 +CCC(N)C(=O)NC1C(=O)N2C(CCC1CNC(=N)N)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +Clc1cccc(-[n+]2nc(-c3ccccc3)nn2-c2ccccc2)c1 +CN1CCN(S(=O)(=O)c2ccc(-c3cnc(N)c(C(=O)Nc4cccnc4)c3)cc2)CC1 +Cc1cn(C2CCCN(Cc3cccc(Oc4cccc(F)c4)c3)C2)c(=O)[nH]c1=O +COc1ccc2cc3[n+](cc2c1OCC=C(C)CCC=C(C)CCC=C(C)C)CCc1cc2c(cc1-3)OCO2 +N#Cc1ncc(F)c(N(Cc2ccc3c(c2)OCO3)CC2CCCC2)n1 +CCOc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCC2)[nH]1 +O=C(c1ccc([N+](=O)[O-])o1)N1CCN(c2nc3ccc(F)cc3s2)CC1 +COCC(O)Cn1cc(-c2ccc3c(c2)N(C2=NC4CC(C)(C)NC(=O)C4S2)CCO3)cn1 +CN(c1ccccc1Cl)S(=O)(=O)c1ccc(NC(=O)c2nccs2)cc1 +CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2c(F)cccc21 +[O-][S+](Cc1nccc(OCC(F)(F)F)c1OCC(F)(F)F)c1nc2cscc2[nH]1 +CC1CCNC(=O)c2cc3ccc(C(=O)Nc4cnn(Cc5ccccc5)c4)cc3n21 +COC(=O)c1cc(O)cc2nc(-c3ccc(O)cc3)oc12 +COc1ccccc1N1CCN(CCCCOc2c(C)cccc2C)CC1 +COCCC1N=C(c2ccc(Cl)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +COc1cc2c(cc1OC)C(=O)N1C=C(c3cccc(N)c3)CC1C=N2 +CN(C)c1ccc(C=CNNC(=O)CCCCCC(=O)NO)c(O)c1 +COC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1cccc(Cl)c1Cl +COc1ccc(CCc2cnc3c(N)nc4cc(CCP(=O)(O)O)ccc4c3c2)c(C)c1 +O=S(=O)(N1CCc2cc(O)ccc2C1)C(F)(F)F +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N(CCO)S(C)(=O)=O)no2)cc1C#N +CCN1CCCN(C(=O)C(Cc2ccccc2)c2ccccc2)CC1 +CC(=CC(C(C)C)N(C)C(=O)C(NC(=O)C(NCCO)C(C)(C)c1ccccc1)C(C)(C)C)C(=O)O +COc1cccc(-c2ccc(C(=O)N3CCN(C(=O)c4ccc5cc[nH]c5c4)C(C)C3)cc2)c1 +CCS(=O)(=O)N(CC(O)C(=O)NO)c1ccc(Oc2ccc(C)cc2)cc1 +CC12CCC(O)CC1=CCC1C2CCC2(C)C(n3ccnc3)=CCC12 +CCCC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NO +CCCN(CCC)CCCOc1cc(C)nc(-c2ccccc2)n1 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nc12 +CCC1CC2=CC(=O)CCC2C2CCC3(CC)C(CCC34C=CC(=O)O4)C12 +CCCN(CCC)C1COc2c(cccc2C(=O)c2ccc(OC)cc2)C1 +NS(=O)(=O)c1ccc(CC[n+]2c(-c3ccccc3)cc(-c3ccccc3)cc2-c2ccccc2)cc1 +O=C(Nc1ccc(C(=O)O)c(O)c1)NC12CC3CC(CC(C3)C1)C2 +CS(=O)(=O)c1csc(NC(=O)c2ccccc2O)n1 +N#Cc1cnc2sc3c(c2c1Nc1ccc(Cl)c(Cl)c1)CCN(C(=O)C=CCN1CCCOCC1)C3 +CCc1nc2c(-c3ccc(Cl)cc3C)nccc2n1C(CC)C1CC1 +COC1CC2CCC(C1)N2c1nc(N2CCCC(C(N)=O)C2)c2c(-c3ccccc3Cl)csc2n1 +CC(C)(C)C1=CSC(=C(C#N)c2ccnc(NC(=O)C3CCNCC3)n2)N1 +CCN(CC)c1ccc(CN(C(=O)Cc2ccccc2)C23CC4CC(CC(C4)C2)C3)cc1 +OCc1cncc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC3)n2)n1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5CCC(C4)N5C)cn3)nc2n1C1CCCC1 +CC(=O)c1cc(NC(=O)NC(C)CCN2CCCC(Cc3ccc(F)cc3)C2)cc(-c2nnnn2C)c1 +CC1CN(C(=O)N2Cc3c(-c4ccc(F)cc4)ncn3-c3cccc(Cl)c32)CC(C)N1C +COc1ccc2[nH]c(C(=O)NC3N=C(c4ccccc4F)c4ccccc4NC3=O)cc2c1 +COc1ccc2c(c1)c(C=C1C(=O)Nc3ccc(C(=O)O)cc31)cn2C +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C12CN(c1ccc(C#N)cn1)CC2c1ccc(C#N)cc1 +Nc1ncc(-c2nc(N3CCOCC3)nc3c2CCN3C2CCN(S(N)(=O)=O)C2)cn1 +CCN(CC)c1ccc(OC)c2nc(-c3c(OC)cc(COC)cc3OC)c(C)cc12 +CC(=O)NC(CCN1C2CCC1CC(n1c(C)nc3c1CNCC3)C2)c1ccccc1 +Cc1nc(C=Cc2c(C)nnn2-c2ccc(F)cc2)sc1C(=O)NC(C)C +Cc1cc(-c2cnn3ccc(N4C(=O)OCC4C(C)C)nc23)ccc1-c1nc[nH]n1 +O=C(CCC(NS(=O)(=O)c1ccc(-c2ccc(Br)cc2)cc1)C(=O)O)NC1CCCCC1 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+O=C1NC(=O)C(c2cncc3ccoc23)=C1c1cn2c3c(cccc13)CNCC2 +C#CCNc1nc(Nc2ccc(S(N)(=O)=O)cc2)ncc1Br +O=C(O)c1ccc(NC(=O)c2ccc3c(c2)N(Cc2cccc(Cl)c2)C(=O)CS3(=O)=O)cc1 +O=C1NCN(c2ccccc2)C12CCN(C1COCCC1(O)c1ccccc1)CC2 +O=[N+]([O-])c1ccc2nc(-c3ccccc3O)[nH]c2c1 +COc1cc2c(cc1NS(=O)(=O)c1cccc(Cl)c1Cl)[nH]c(=O)n2C +O=C1OCC(C2CCCC2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(-c2cn[nH]c2)cc1F +CSc1ccc2c(c1)CCC2C(CS)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +CC1CN(C(=O)C(C)(O)C(F)(F)F)CCN1S(=O)(=O)c1ccccc1 +CC(C)CCC#Cc1cc2c(cc1N1CCN(C3COC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +COc1cccc(-c2ccc3c(c2)Nc2ccccc2NC3=O)c1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(-c2ccccc2Cl)cc1F +O=C(NCc1ccc(F)cc1)C1C(=O)N(O)C(=O)c2cc(Br)ccc21 +COc1cc(-c2ccncc2)cc2cnc(Nc3ccc(C(C)NC(C)=O)cc3)nc12 +CCNC(=O)C1OC(n2cnc3c(N)[n+](Cc4ccccc4[N+](=O)[O-])cnc32)C(O)C1[O-] +OCC1CC(Nc2nc(Nc3cncnc3)ncc2-c2nc(-c3ccccc3)cs2)C(O)C1O +COc1cc(-c2cn(C3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)ccc1-n1ccnc1C 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+O=C(O)c1ccc(CNc2ccc3c(C=Cc4cccc(C(F)(F)F)c4)cccc3c2)cc1 +O=C(COc1cccc2[nH]cc(S(=O)(=O)c3ccccc3Cl)c12)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +CCCC(C)(O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 +CCN(CC)CCCCNC(=O)C1C(C(=O)NCc2ccc(Br)cc2)C2C=CC1C21CC1 +CC(C(=O)O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 +CCN1CCN(c2cccc3c2CN(C(CCCNS(=O)(=O)c2c[nH]cn2)c2ccc(OC)c(OC)c2)C3=O)CC1 +O=C(NC(Cc1ccc(CCCCNc2ccccn2)cc1)C(=O)O)c1c(Cl)cccc1Cl +O=C(C=Cc1cccc2c1N(Cc1ccc(F)c(F)c1)C(=O)C2)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +O=C(Nc1ccc(F)c(OCCCN2CCOCC2)c1)NC12CC3CC(CC(C3)C1)C2 +CC(NC(=O)c1nn(-c2ccc(C(F)(F)F)cc2Cl)c2c1CCCCC2=Cc1ccc(Cl)s1)c1ccccn1 +NC(Cc1cccc(F)c1)C(=O)Nc1ccc(-c2cn[nH]c2)cc1 +Nc1[nH]cnc2c(CN3CC(O)C(CSCc4ccccc4)C3)cnc1-2 +CC(C)N1CCCN(C(=O)C(Cc2ccccc2)c2ccccc2)CC1 +COC(c1ccccc1)c1ccc(-c2nc3cc(C(N)=O)ccc3[nH]2)cc1 +Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)N1CCN(S(C)(=O)=O)CC1 +CN1CCN(c2ccc(Nc3nc4cccc(-c5ccc(NS(C)(=O)=O)cc5)n4n3)cc2)CC1 +O=C(O)CC1(Cc2nc3cc(F)ccc3n2Cc2ccc(Cl)cc2)CCCC1 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+COc1ccc(CCNCC(O)COc2ccc(-c3nc(C(C)(C)C)c[nH]3)cc2)cc1OC +CC(C)(C)C1CCc2onc(C(=O)Nc3cnn(Cc4ccccc4)c3)c2C1 +COC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(C)C +C=CC(=O)N1CC(Oc2cc3c(NC(C)c4ccccc4)ncnc3cc2OC)C1 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(F)cc1 +CCCN(CC1CC1)c1nc(CC)c(-c2ccc(Cl)cc2Cl)nc1CC +Cc1cccc(-c2nc3c(NC4CC(O)C(COS(N)(=O)=O)C4)ncnc3[nH]2)c1C +N#Cc1cnc2[nH]cc(C(=O)c3cccc(NS(=O)(=O)c4c(F)cccc4F)c3F)c2c1 +CN(C)CCOc1ccc2c(c1)Nc1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn1CC2 +CC1Cc2c(ccc(F)c2Cl)N1C(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1 +CCN(C)C(=O)c1ccc(C(c2cccc(NC(=O)C3CCC3)c2)N2CCN(Cc3cccnc3)CC2)cc1 +Cc1nn(-c2ccccc2)c(Cl)c1CN1CCN(c2ccc(F)cc2)CC1 +CC(C)CC(NC(=O)Nc1ccc(Br)cc1)C(=O)NC(C)(C)C(=O)O +CCCN(Cc1ccc2ccccc2c1)c1ccc2nc(N)nc(N)c2c1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(N)Cc3ccccc3)c2=O)c1F +CCCCCCCC(=O)Nc1nn(C)c2ncnc3c2c1cn3C1OC(CO)C(O)C1O +O=C1c2cc3c(cc2C2(CC2)N1CCC1CCN(Cc2c(F)cccc2F)CC1)OCO3 +COc1cc(C#CC2CCCC2)c(F)cc1-n1c(=O)cnc2cc(S(=O)(=O)Nc3ccon3)ccc21 +O=C(O)C1CCC2(CCN(c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)CC2)CO1 +CCc1[nH]c2nc(Sc3ccc4ccc(C(=O)O)nc4c3)nc(N3CCC(N)C3)c2c1Cl +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCCc4ccccn4)nc23)N1 +COc1ccc(C(c2ccncc2)c2cc3c4c(c2)CCN4C(=O)CC3)cc1 +CCCn1c(=O)c2nc(-c3cc(OCC(=O)Nc4ccc(OC)c(OC)c4)nn3C)[nH]c2n(CCC)c1=O +O=C(CN1CCCCC1)Nc1scnc1C(=O)Nc1nccs1 +O=C(O)Cn1c(=O)c(C=Cc2ccc(F)cc2)nc2cc([N+](=O)[O-])ccc21 +Cn1ncc2cc(-c3cccc(OCC(O)CN4CCc5ccccc5C4)c3)ccc21 +CC(C)C(NC(=O)COc1cc2ccccc2cc1C(=O)O)C(=O)NC1CC(=O)OC1O +CCCCCCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc21 +Cc1cc(CSc2nnc(Nc3ccc(Cl)cc3)[nH]2)no1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(N2CCCC2)nc1C +Oc1cc2c(cc1O)C1c3cc(-c4ccccc4)sc3CNC1CC2 +Nc1ncc(CN2CCc3c([nH]c4ccccc34)C2)c(N)n1 +COc1ccc(NC(=O)Nc2nc3nn(C)cc3c3nc(-c4ccc(Br)cc4)nn23)cc1 +O=C(NC(Cc1ccc2nc(-c3cc(C(F)(F)F)ccc3Cl)ccc2c1)C(=O)O)c1c(Cl)cccc1Cl +Cc1ccc(C(=O)N2CCc3c(cc(Cl)c(C(=O)NC(CNC(=O)c4cccs4)C(=O)O)c3Cl)C2)cc1 +COc1ccc(NC(=O)c2cc3n(n2)CCCN(C(=O)c2occc2C)C3)cc1 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+CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3cccc(CN(C)C(=O)C(F)(F)F)c3)nc2n1 +CC1(CO)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 +CN(C)C(=O)CCN1CCN(CC2CC2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(Cl)c(Cl)c2)CC1 +CC(=O)NC1C(NC(=N)NC(=O)CCn2cc(-c3ccccc3)nn2)C=C(C(=O)O)OC1C(O)C(O)CO +Cn1c(=O)cc(N2CCCC(C)(N)C2)n(Cc2cc(F)ccc2C#N)c1=O +O=C(O)c1ccc(O)c(C(=O)C=Cc2ccc(C=Cc3ccc4ccccc4n3)cc2)c1 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cccc(F)c3)c(F)c2)CC1 +COc1cc(-c2c(-c3ccncc3)nn3c(-c4ccc(N5CC6CCC(C5)N6C)cc4)ccnc23)ccc1Cl +C=C(c1cccc(OCCCC)c1)C1CNC(C(=O)O)C1CC(=O)O +COc1cccc2c1CCC2C(CS)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1 +CCNC(=O)C1OC(n2cnc3c(NCc4ccco4)ncnc32)C(O)C1O +O=[N+]([O-])c1ccc(NCCOCCOc2cccc3c2CCCC3CCCN2CCN(C3CCCCC3)CC2)c2nonc12 +COc1ccccc1N1CCN(Cc2cn(-c3cccc4ccccc34)c3ccccc23)CC1 +CNC(=O)COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +COc1cc(-c2cc(C(=O)NC3CCCN(C(=O)C4(N)CC4)C3)c3c(N)ncnn23)ccn1 +CN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(c3ccccc3OC(F)F)=NN12 +CCCC(=O)Nc1n[nH]c2ncc(-c3cccc4ccccc34)cc12 +CCCCCCCCCC=Cc1cc2ccccc2n1C(=O)CCCC(=O)O +CCOn1c(Sc2ccccc2)c(CC)c(=O)[nH]c1=S +CCN1CCN(C(=O)c2cc(Sc3cnc(Nc4cccc(Br)n4)s3)ccc2C)CC1 +COc1cc(-c2ccc3c(-c4nc5c(N6CCN(C)CC6)cccc5[nH]4)n[nH]c3c2)ccc1O +O=C(Nc1ccn2cc(-c3ccc(F)c(F)c3)nc2c1)N1CCC(F)C1 +COc1ccc(C(=O)Nc2ccc(CCN3CCc4cc(OC)c(OC)cc4C3)cc2)cc1NC(=O)c1cnc2ccccc2c1 +[O-][n+]1nc2c(I)cnn2c2cc(-c3ccccc3)ccc21 +O=C(C1CCCN(c2ccc3nc(-c4cncc(C5CC5)n4)[nH]c3n2)C1)N1CCCC1 +CC(NC(=O)C(CS)Cc1ccccc1Cl)C(=O)N1CCCC1C(=O)O +O=C(Cn1ncc2ccccc21)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +CCc1cc(CC)nc(OCCCn2c3c(c4cc(C(=O)OC)ccc42)CCCC3)n1 +O=c1c2cc(O)c(O)cc2oc2cc(O)c(C3OC(CO)C(O)C(O)C3O)c(O)c12 +O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc4ccccc34)ccc1-2 +COc1ccc(-c2ccc(C(N)=O)cc2Cl)cc1OC1CCCC1 +CC(C)(C)CC(O)C(=O)N1CC2CC2C1C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +NC1=NC(=O)C2C(N=C(c3ccccc3)N2C2OC(CO)C(O)C2O)C(=O)N1 +COc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)cc2)c2ccccn2)CC1 +CCCc1c(OCCCCOc2cccc(C(=O)O)c2)ccc2c(-c3ccccc3)noc12 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+N=C(N)NCCCC1CC(OCc2ccc3ccccc3c2)CN1C(=O)C(Cc1ccccc1)NC(=O)CCc1ccccc1 +CN1CCC(COc2ccc3c(Nc4ccc(CC(=O)Nc5ccc(Cl)c(C(F)(F)F)c5)cc4)ncnc3c2)CC1 +O=C(Nc1cc(C2CN(C3CCC3)C2)nn1-c1ccc(C2CC2)cc1F)c1cnn2cccnc12 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc(-c4cccc(S(N)(=O)=O)c4)cn3)C12 +COc1ccc2c(c1)CC(C(=O)Nc1ccc(-c3c[nH]nc3C)cc1SCCN(C)C)NC2 +COc1cccc(COc2ccc3sc4c(c3c2)NCC(C)NC4=O)c1 +Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3cccnc3)nc21 +Cc1cc(C)nc(N2CC3CN(C(=O)c4cccc(F)c4-c4ccccn4)CC3C2)n1 +NC(=O)c1cccc2c(NCc3cccc(OCCN(CCO)CCO)c3)ncnc12 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccc(CC(=O)O)cc3)n2)CC1 +COc1cc(-c2cn[nH]c2)c(F)cc1NC(=O)C1COc2ccccc2C1 +O=C(c1cccc(-c2cccc(O)c2F)n1)c1ccc(F)c(O)c1O +Nc1ncc(-c2nc(N3CCOCC3)c3sccc3n2)cn1 +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cccc(N2CCN(c3ccc(O)cc3)CC2)n1 +CN(Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1)C1=NCCN1 +CCN(CC)CCCOC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)CC1 +COc1ccc(C(C#N)(CCCNC2c3ccccc3CCc3ccccc32)C(C)C)cc1OC 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+O=C(C=Cc1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21OCCO1)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +CC(C)(C)NC(=O)NC1CCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)C1 +Fc1cc(F)c(CNc2ccc(Oc3ccccc3C(F)(F)F)cn2)c(F)c1 +COC(=O)c1c(CNC(=O)c2cccc(F)c2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +CCCn1c(=O)c2nc(-c3cc(OCC(=O)Nc4ccc(OC)c(OC)c4)no3)[nH]c2n(CCC)c1=O +CC(C)(C)c1cc(C(=O)Nc2cccc(CN)n2)n(Cc2ccccc2)n1 +O=C(CCCN1CCN(c2ccc([N+](=O)[O-])cc2)CC1)NC1c2ccccc2CSc2ccccc21 +Cc1ccc2[nH]c(C)c(C=Cc3cc[n+](C)cc3)c2c1 +CC(C)OC(=O)c1oc(N)nc1-c1ccc(P(=O)(O)O)o1 +CC1(O)CCC(NC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(Cl)cc3Cl)n(-c3ccccc3)n2)CC1 +CCc1nc(Nc2ccc(C(=O)O)cc2)nc(-c2ccc(Cl)s2)n1 +CC(C)CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O +CCCCN(CCCC)CCNCC(O)c1ccc(O)c2[nH]c(=O)sc12 +O=c1[nH]c(N2CCC(F)(F)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +O=C(O)Cc1ccc(F)c(-c2cccc3c2CN(C(=O)OCc2ccccc2)CC3)c1 +C=C(C)C1CCC2(NC(=O)NCCO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(-c5cn(C)c6cnccc56)cc34)cn2)CC1 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+CCCCCCCCCCCCn1c2nc(=O)[nH]c(=O)c-2cc2c([N+](=O)[O-])cccc21 +CN(C)CCN1C(=O)c2c(N)ccc3cc4c(c(c23)C1=O)CCCC4 +Cc1cc(OCCC(C)Oc2ccc(C(F)(F)F)cc2Oc2ccccc2)ccc1CCC(=O)O +COCCNC(=O)c1cn2cc(-c3cnc(N)nc3)nc(N3CCOCC3)c2n1 +CC12C=CC(=O)C=C1C=CC1C2CCC2(C)C(=O)CCC12 +C=CCN1CC(C)N(C(c2ccc(C(=O)N3CCCC3)cc2)c2cccc(OC)c2)CC1C +O=C1Nc2ccc(-c3n[nH]c(C4CCCCN4C(=O)COc4ccccc4)n3)cc2CO1 +O=[N+]([O-])c1cccc(NN=Cc2cc([N+](=O)[O-])ccc2O)c1 +CN(C)Cc1ccc(C(=O)Cn2ncc(OCc3ccccc3)cc2=O)cc1 +CS(=O)(=O)c1cnc(OC2CCC(OC3CCN(C(=O)OC(CF)CF)CC3)CC2)cn1 +CCC(C)CNc1cc(-c2[nH]c(SC)nc2-c2ccc(F)cc2)ccn1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1cc(F)cc(F)c1)Oc1ccccc1-3 +O=C(CCCC1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)c1ncco1 +C#CC1(O)CCC2C3CCC4=Cc5nc6nc7ccccc7n6cc5CC4(C)C3CCC21C +Cc1ccc2nc3c(C(=O)NCCCN(C)CCCNC(=O)c4cccc5nc6cc(C)ccc6nc45)cccc3nc2c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3C)C2)cc1 +O=C(Nc1ccccc1)c1ccn(C(=O)c2ccccc2)n1 +CCCCCNC(=O)Nc1c(C)cccc1C[S+]([O-])CCn1cnc(-c2ccccc2)c1C +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2c(cnn2CCO)c1 +CCCOc1ccc(C(=O)C(CN2CCOCC2)c2ccccc2)cc1 +Cc1ccc(NC(=O)c2cc[n+](CCCCCCCCCC[n+]3ccc(C(=O)Nc4ccc(C)cc4)cc3)cc2)cc1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C5CCCC5)no4)c3)c2cc1OC +CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C +Cc1ccc(NC(=O)c2ccc(Cl)cc2)cc1Nc1nc(-c2cccnc2)c[nH]1 +O=C1NC(=O)C(c2cccc(OCCCOc3ccc(Oc4ccccc4)cc3)c2)S1 +Cc1cc(C)cc(NC(=O)c2cccnc2SCc2ccnc(C)c2)c1 +CC1CN(Cc2ccccc2)CC1c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1 +COc1cc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC4CCCN4CC2C)C3(C)C)nc(OC)n1 +N#CC1=C(c2cccc3ccccc23)CN(C(=O)CCc2cncn2Cc2ccc(C#N)cc2)CC1 +COc1ccc(C2(C(=O)NC(Cc3ccc(NC(=O)c4ccnc5ccccc45)cc3)C(=O)O)CCCC2)cc1 +Nc1nc2c(ncn2C=C2CC23CCP(=O)(O)OC3)c(=O)[nH]1 +CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1C(=O)OCC +O=P(O)(O)C(O)(Cc1cccc(Br)c1)P(=O)(O)O +CC(C)(C)N=c1c(O)c(O)c1=NC(Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)C(=O)O +CCC(Nc1ncnc(N)c1C#N)c1nc2cccc(C#CCCCC(=O)N3CCOCC3)c2c(=O)n1-c1ccccc1 +CN(CC1=Nc2c(N)nc(N)nc2N(Cc2ccccc2)C1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +NC(=O)c1cccc2[nH]c(-c3ccc(C4CCCCN4)cc3F)nc12 +CC(NC(=O)C(F)(F)F)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OC2CCC3(CCCCC3)CC2)cc1F +O=C(O)CCCCCCN1C(=O)CCC1C=CC(O)c1cccc(-c2ccccc2)c1 +CC(=O)N(C)CCCOc1ccc(C(=O)N2CCC(N3C(=O)CCc4ccccc43)CC2)cc1 +CON=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1ccc2c(ccn2C)c1 +C#CC1CCC(C#N)N1C(=O)CNC1(C)CCN(c2cc(C(=O)O)ccn2)CC1 +CCCCC(Sc1nc(OCCc2ccsc2)cc(OCCc2ccsc2)n1)C(=O)O +CN(C)C(=O)Cc1cc(-c2ccncc2)c(-c2ccc(F)cc2)[nH]1 +Oc1noc(C2CCNCC2)c1Cc1ccc2ccccc2c1Br +CCOc1ccc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)OCC3(F)F)c2)nc1 +COc1ccn2ncc(C=NN(C)S(=O)(=O)c3cc([N+](=O)[O-])ccc3C)c2n1 +O=C(O)C1CCCN(CCC=C(c2sccc2COc2ccccc2)c2sccc2COc2ccccc2)C1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(C4CC4)c3c2)c1F +CC(C)C(=O)N1CC(CC=CCCC(=O)O)C(c2ccccc2O)C1 +CS(=O)(=O)CC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)CC1CCC1 +CC(C)c1ccc(N2CCc3cc(O)ccc3C2(C)c2ccc(OCCN3CCCC3)cc2)cc1 +CC(C)(C)OC(=O)N1CCC(c2ccc(Cl)cc2)C(COc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1 +CCSC1=C(c2ccc(O)cc2)C(=O)c2ccc(O)cc21 +c1cc2c(c(-c3nc4cccnn4c3-c3ccncc3)c1)OCO2 +CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(-c3cccc(N)c3)ccc21 +COc1ccc2[nH]cc(CCCN3CCN(CCCc4c[nH]c5ccccc45)CC3)c2c1 +CC(=O)Nc1cccc(C2CCN(CCCC(=O)c3ccc(C)c(C)c3)CC2)c1 +Cc1ccc2c(NCCNc3ccnc4cc(C)ccc34)ccnc2c1 +CNC(=O)C(CC(C)C)CC(O)C(Cc1ccccc1)NC(=O)c1cncc(Br)c1 +C#CCOC(=O)CC1C(C(=O)OCC#C)=C(N)Oc2ccc(-c3cc(OC)cc(OC)c3)cc21 +C=CCN1C(=O)C(=C2Sc3ccc(OC)cc3N2C)SC1=Nc1ccccc1-c1ccccc1 +Nc1nc(-c2cc3c(s2)-c2ccccc2OCC3)c(-c2ccccc2Cl)s1 +CC(NC(=O)C1(Cc2ccccc2)OC(=O)N(C(C)c2ccccc2)C1=O)c1cccc(Cl)c1 +CNC(=O)C(NC(=O)C(CC(C)C)C(Sc1ccc2c(c1)CCC(=O)N2C)C(=O)NO)C(C)(C)C +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1cccc2ccccc12 +CC(=O)N1CCN(c2nccnc2OC2CN(C(=O)c3nc4ccccc4[nH]3)C2)CC1 +O=C(CC(NC(=O)c1ccc(C#Cc2ccccc2)cc1)C(=O)NO)NCCCO +CCCn1c(C)c(Cl)c2cc(Nc3nccc(-n4cc(CN5CC(O)C5)c(C)n4)n3)ccc21 +O=C(C=Cc1ccc([N+](=O)[O-])cc1)Nc1cc(-c2ccc(Br)cc2)[nH]n1 +O=C(NCCN1CCCC1)c1cc2cnnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2[nH]1 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+O=C(Nc1ccc(CC(NC(=O)C2CCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)C(=O)O)cc1)c1c(Cl)cccc1Cl +Cc1ccc(CCC(=O)NC23CCC(=O)C4Oc5c(O)ccc6c5C42CCN(C)C3C6)cc1 +COc1ccccc1-n1nc(OC2CC(C)(C)[S+]([O-])C(C)(C)C2)cc1-c1ccc(C#N)cc1 +Cc1cccc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c12 +O=C(CCN1CCCCC1)Nc1ccc2cc3ccc(NC(=O)CCN4CCCCC4)cc3nc2c1 +CC(=O)C1CC(NC(=O)C(N)CCCNC(=N)N[N+](=O)[O-])CN1 +Cc1c(CC(=O)OCCO)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccccc1 +CC(=O)N1CCc2c(ncnc2Oc2ccc3c(ccn3C(=O)Nc3cccc(C(F)(F)F)c3)c2)C1 +O=C(NC(=O)c1c(F)cccc1Cl)Nc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl +N#Cc1c[nH]c(C(=O)Nc2ccc(-c3ccc(N)cc3)cc2C2=CCCCC2)n1 +CC1C(c2ccccc2)C1(NS(=O)(=O)N1CCn2c(nc3ccc(F)cc32)C1)C(=O)O +C=CCCCCCCOCCCCCCOC1CC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CO1 +NCCCCC(NC1CCc2ccccc2N(CC(=O)O)C1=O)C(=O)O +Nc1nccc2ccc(OCCN3Cc4cc(-c5ccccc5S(N)(=O)=O)ccc4C3=O)cc12 +Cc1nc2cnccc2n1CCN1CCN(C(=O)c2cn(C(=O)N(C)C)c3cc(-c4ccc(F)cc4)ccc23)CC1 +COc1ccc2[nH]c(-c3cccc(O)c3)c(-c3ccncc3)c2n1 +Clc1ccc(C(c2cccnc2)N2CCN(c3ccccc3)CC2)cc1 +CSCCOc1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(C(=O)O)c1 +CN1C(=O)N(Cc2cc(F)ccc2F)C(=O)C12C(=O)N(CC(=O)O)c1ccc(Cl)cc12 +COc1cc2ncnc(N3CCN(C(=O)Nc4ccc([N+](=O)[O-])cc4)CC3)c2cc1OC +O=C1NC(=O)c2cc3c(Cl)c(-c4ccccc4)[nH]c3cc21 +Cc1cccnc1-c1cc(N2CCC3(CC2)CN(C)C(=O)O3)ncc1Cl +C[n+]1c(-c2ccccc2)nn(CC(=O)CCc2ccccc2)c1-c1ccccc1 +Cc1cc2c(C)ccc(-n3c(C)nnc3SCC(=O)Nc3ccccc3Br)c2cc1C +O=C(NO)c1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c2ccco2)cc1 +Cc1ccc(C)c(Cn2cc(CC(C)Nc3ncnc4c3ncn4C3OC(C(=O)NC4CC4)C(O)C3O)c3ccccc32)c1 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)C2)CCN1Cc1ccc(Cl)c(Cl)c1 +O=c1[nH]c2cc(-c3ccc(F)cc3)ccc2cc1O +COCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(=O)CC(F)(F)F)c1 +NS(=O)(=O)Oc1ccc2nc(C=C3C4CC5CC(C4)CC3C5)oc2c1 +CN1CC(c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1=O +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)N4CCC4)ccc3N2)c(O)c2cccnc21 +CC(=O)Nc1cccc(Cn2c(C(=O)O)c(-c3ccccc3F)c3cc(Cl)ccc32)c1 +CC(C)(CO)NC(=O)c1nn(-c2cc(F)ccc2F)c2c1CC1CC21 +O=C(Nc1nocc1Cl)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +Cc1cccc(Cl)c1Nc1nc2cc(C(=O)NC3CCC(C(F)(F)F)CC3)c3c(c2[nH]1)OCCO3 +Cc1cn(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2C(F)(F)F)cn1 +O=C1Nc2ccc(C(=O)O)cc2C1=NNc1ccccc1C(=O)O +COc1cc2c(cc1OC)C1(O)C(=O)c3ccc4c(c3OC1CO2)C=CC(C)(C)O4 +CN1C(=O)C(NC(=O)c2ccc(Cl)cc2)N=C(c2ccccc2F)c2ccccc21 +Cc1noc(-c2cnn3c2n[n+]([O-])c2ccc(OCc4ccccc4)cc23)n1 +CC(C)(C(N)C(=O)N1CC(F)CC1C#N)S(=O)(=O)Cc1csc2ccc(Cl)cc12 +CN(C)c1ncc(-c2cccc(OCC(O)CN3CCc4ccccc4C3)c2)cn1 +COc1ccc(C(=O)C=Cc2ccc(O)c(O)c2)c(O)c1 +CC12CCC3c4ccc(O)c(F)c4CCC3C1CCC2(O)Cc1ccccc1 +CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)Nc2nc(CC(=O)NO)cs2)n1 +CN(CCO)c1ccc(C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)cc1 +COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1N(C)CCCN(C)C +N#Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 +NC(=O)c1sc(-c2ccnc(N)n2)nc1-c1ccc(Cl)cc1Cl +C=CC(=O)Nc1cccc(N2C(=O)N(C)Cc3cnc(Nc4ccc(N5CCCCC5)cc4OC)nc32)c1 +CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 +CC(C)(C)NCC(=O)N1CCCC1C(=O)c1noc(-c2ccc(F)cc2)n1 +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCCC(O)CC2)C1 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+O=C(Nc1ccc([N+](=O)[O-])cn1)C1CC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C(O5)C1=O +Nc1nccn2c(C3CCC(CO)CC3)nc(-c3cc4ccccc4[nH]3)c12 +Cc1cc(C(=O)N2CCC3(CC2)CN(C(=O)OCC(C)(C)C)C3)cc2cn[nH]c12 +COCCN1CCC(NC(=O)c2ccc(Nc3ncc4c(n3)-c3c(nn(C)c3-c3ccccc3C)CC4)c(Cl)c2)CC1 +CN(C)CCn1c(=O)c2ccc(NCCN)c3c(=O)c4ccccc4n(c1=O)c23 +COCCCN1CCN(C(=O)c2cc3c(cc2C)[nH]c(=O)c2cnn(CC4CC4)c23)CC1C +CC(Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O)C(C)(C)C +COC(=O)C1=C(CN2CCOCC2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1C +COc1cc(-c2ccc3ncc(C(C)=O)c(NC4CCC(N)CC4)c3c2)cc(Cl)c1O +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)O)cc3)[nH]c2n(CCc2ccc(N)c(I)c2)c1=O +O=C(c1ccc2c(c1)CCNC2)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1 +CC(CSc1ccc(-c2ccccc2)cc1)(C(=O)NO)S(C)(=O)=O +CCCCCCCCC=CCCCCCCCCNC(=O)Nc1c(C(C)C)cccc1C(C)C +CN1CCN(CCCC=Cc2ccc3c(Nc4ccc(Sc5nccn5C)c(Cl)c4)c(C#N)cnc3c2)CC1 +COc1cc(C2=C(c3c[nH]c4cnccc34)C(=O)NC2=O)cc(OC)c1OC +O=C(COc1ccc(C(=O)c2ccccc2)cc1)Nc1cccnc1 +Cc1nnc2n1-c1sc(C#Cc3ccc4c(c3)CCO4)cc1C(c1ccccc1Cl)=NC2 +CCN(C)C(=O)c1ncncc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +O=C(NCC1CCCCC1)c1cccc(C(O)(c2ccc(Cl)cc2)c2cccnc2)c1 +CCC1(c2cccc(COc3ccccc3)c2)Oc2ccccc2-n2cccc2C1=O +COc1ccc(S(=O)(=O)N(Cc2ccccc2)C(C)C(=O)NO)cc1 +O=C(Nc1ccc(C2CCNC2)cc1)c1ccc(Br)cn1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)cc2c(=O)n(CC(N)=O)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +NS(=O)(=O)c1ccc(NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)c(Br)c1 +COc1cc(C(=O)n2ccc3cc(C)ccc32)cc(OC)c1OC +CCCCS(=O)(=O)N(Cc1ccccc1)c1ccc2ncn(Cc3ccc(-c4ccccc4-c4nnnn4C)cc3)c(=O)c2c1 +CCC(C(=O)Nc1ccc(C(=O)O)cc1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O +CCC(C)(C)NCC(O)c1cc(OC(=O)N(C)C)cc(OC(=O)N(C)C)c1 +COc1cc(Sc2c(-c3ccccc3)[nH]c3cc(F)ccc23)cc(OC)c1OC +O=C1NC(=O)C(Cc2ccc(Oc3ccc(Cl)cc3Cl)cc2)S1 +Cc1sc2c(c1C)C(N1CCN(C)CC1)=Nc1cc(F)ccc1N2 +Cn1nc(-c2cnccc2C(F)(F)F)c2ncc(OCc3ccccn3)nc21 +CC(NP(=O)(Nc1ccn(C2CSC(CO)O2)c(=O)n1)NC(C)C(=O)OCc1ccccc1)C(=O)OCc1ccccc1 +COc1cccc(Sc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)noc2C)c1 +N#CC(Cc1ccc(-c2cn[nH]c2)cc1F)NC(=O)C1NC2CCC1C2 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+Nc1ncnc2c1nc(NCc1ccc(F)cc1)n2C1OC(CO)C(O)C1O +CC(=O)OC1CC(Nc2nc3c(nc2N2CCN(Cc4ccc(F)cc4F)CC2)CCN(C(C)=O)C3)C1 +COc1ccc(N(C)c2nc(Cl)nc3ccccc23)cc1OC +COc1ccc(CCNc2nc(NCCCN3CCCCC3C)ncc2C(=O)NCc2ccccc2)cc1OC +COC(=O)c1cccc(-c2nnc(C(=O)CCCCCCc3ccccc3)o2)n1 +Cc1c(Cn2ncc(N3CCNCC3)c(Cl)c2=O)cccc1NC(=O)c1ccc(-c2cccc(C(N)=O)c2)cc1 +Nc1nccc(-c2nc(C3CC3)[nH]c2-c2cc(F)cc(NS(=O)(=O)c3c(F)cccc3F)c2Cl)n1 +CC(=CCN1CCCCC1)c1ccc(-c2ccccc2)cc1 +O=S(=O)(Nc1cccc(B(O)O)c1)c1cccc(S(=O)(=O)Nc2cccc(B(O)O)c2)c1 +CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccnnc2)ncc1Cl +CC1(c2nc(NC(=O)c3ncc(Cl)cc3Cl)ccc2F)N=C(N)OCC1(F)F +COC1N(C2CC(N=[N+]=[N-])C(CO)O2)C(=O)NC(=O)C1(C)Br +COc1ccc(Sc2ccc(Cl)cc2N2CCN(CC(=O)O)C(C)C2)cc1 +CN1C2CCCC1CC(Nc1nc(-c3ccc(Oc4ccc(F)cc4)cc3)c3ccccc3n1)C2 +O=C1c2ccccc2CCCN1CCCN1CCN(c2cccc(Cl)c2Cl)CC1 +CCCC#CCOc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 +Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC2(CCOCC2)c2nc(Cl)c(N3CCOCC3)cc21 +O=C(O)C1=Cc2c(ccc(Cl)c2Oc2ccccc2)OC1C(F)(F)F +O=C(NCCN1CCOCC1)c1ccc(Nc2nccc(Nc3ccccc3Cl)n2)cc1 +CN1C(=O)C(c2ccncc2)(c2cccc(-c3cnccn3)c2)N=C1N +Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3ccc([N+](=O)[O-])cc3)CC2)c(C)c1 +C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(OCc4ccccn4)c(Cl)c3)ncnc2cc1OCCOC +CN(C)CC1CCc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc2C1 +O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cccc(F)c21 +CC(=O)Nc1ccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2F)cc1 +Cc1cc2c(ccc3c(=O)cc(-c4ccccc4)oc32)o1 +COC(=O)C(c1cccc(C)c1C)N1CCC(CCN2C3CCC2CC(n2c(C)nc4ccccc42)C3)(c2ccccc2)CC1 +CC(C)(O)C1CCN(Cc2cc3nc(-c4c(F)ccc5[nH]ccc45)nc(N4CCOCC4)c3s2)CC1 +Cc1ccc(-n2nccn2)cc1CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1ccc(F)c(NS(N)(=O)=O)c1 +Cc1c(-c2ccc(-c3ccc(C(F)(F)F)cc3)nc2)[nH]c2ccccc2c1=O +CCCN(CC1CC1)c1cc(C)nc2c(-c3ccc(OC)cc3OC)c(C)nn12 +O=S(=O)(Nc1ccc2c(c1)C(C1CCNC1)=CC2)c1c(Cl)nc2sccn12 +CCCC(C)(C)C(=O)NCc1ccc2c(cnn2-c2ccc(F)cc2)c1 +CC(C)(C)c1ccc(C(=O)CC(=O)c2cc(Cl)ccc2O)cc1 +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N3CCCCCC3)nc2c1 +NC(=O)c1sc2nc(-c3cccc(F)c3)ccc2c1N +CC12CCC(O)CC1CCC1C2CCC23CC=CC(=O)C2CCC13 +COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cn1cc(Cl)c2ccc(NC(=O)OC3CCCC3)cc21 +Cc1cc(-c2cc(Cl)cnc2Oc2ccc(C(=O)c3nc4ccccc4n3C)cc2)ccn1 +O=C(NC1N=C(c2ccccc2F)c2ccccc2-n2cnnc21)OCc1ccccc1 +COc1ncc(-c2ccc3nc(NC(=O)NCCN4CCOCC4)sc3c2)cc1NS(=O)(=O)c1ccc(F)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CN(C)CC4c4ccc(F)nc4)ncc23)ccn1 +COc1cc2c(N)nc(N3C(C)CN(C(=O)CC(NC(C)C)c4ccc(C#N)cc4)CC3C)nc2c(F)c1OC +CN1CCN(CCN(C)C(=O)c2cc3cc(Nc4nccc(-c5cn(C)cn5)n4)cc(Cl)c3[nH]2)CC1 +NC(=O)CC(Nc1cccc(O)c1)C(=O)Nc1nc2ccc3[nH]ncc3c2s1 +CCOc1nccc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c1OC +COc1cc(-c2cn(C3CCc4ccccc4N(C)C3=O)nn2)ccc1-n1cnc(C)c1 +CC(=O)Nc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 +CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1Nc1nnc(-c3cnccn3)s1)c1c(O)ccc(Cl)c12 +CCC(CCS(C)(=O)=O)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +O=C(O)c1cncc(-c2noc(C3CCCCN3C(=O)COc3ccccc3)n2)c1 +CC(c1ccc(-c2ccccc2)cc1)C(NC(=O)C(C)(C)N)C(=O)NC(c1ccc(Cl)cc1)C(F)F +CC(C)n1nc(-c2ccccn2)cc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1 +CN1CC2CC1CC2OC(=O)C(C)(c1ccccc1)c1ccccc1 +COc1cc(-c2ncn(C)c2-c2ccc3c(c2)c(Cl)cn3C)cc(I)c1OC +Cc1cc(N2CC3CCN(C(=O)c4ccc(C)nc4-n4ccnn4)CC32)nc(C(F)(F)F)n1 +CC(C)c1cccc(C=CC2C3CCCCC3CC3C(=O)OC(C)C32)n1 +Cc1cc(SCc2ccc(OCc3ccc(C(F)(F)F)cc3)cc2)c2c(c1OCC(=O)O)CCC2 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4nccnn4)ccn23)c1 +O=C(O)c1ccc(-c2c(CCc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cc1O +CCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)cn1 +CN(C)CCn1c2c3c(n[nH]c(=O)c4cccc1c34)CN(C(=O)C1CC1)C2 +Nc1nc(NCc2cccc(O)c2)nc2sc(-c3ccco3)nc12 +CC(C)(CNS(C)(=O)=O)c1nc(-c2ccc(Cl)c(O)c2)c(-c2ccncc2)[nH]1 +C=Cc1c(N)ncnc1N1CCN(C(CN)c2ccc(C(F)(F)F)cc2)CC1 +CCSCC1CC(O)(c2ccccc2)CC(c2ccccc2)O1 +COc1ccc2c(c1)C(CCNC(C)=O)CC(c1cccc(NC(C)=O)c1)C2 +OCC1OC(n2cnc3c(CSc4ccc(Br)cc4)ncnc32)C(O)C1O +N#Cc1ccccc1-c1ccc(CSc2nnc(-c3ccncc3)o2)cc1 +O=C1CCC(CCNCc2ccc(Cl)cc2)N1CC1(N2CCCCC2)CCCC1 +CCN(CC)CCn1nc2c3ccc(O)cc3sc3c(NCCN)ccc1c32 +CCCn1nc(CC)c(C(=O)O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(NC(=O)C(F)F)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 +Nc1ccc2c(c1)oc1c(N3CCNCC3)c(F)cc3c(=O)c(C(=O)O)cn2c13 +CC(OC1CCN(C)C(=O)CC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnc2ccc(F)cn12 +Cc1ccc(C(=O)Nc2cc(N(C)CCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCCCC3)nc12 +CCc1nc2cc3c(cc2o1)CCN(CCCSc1nnc(-c2ccc(C(F)(F)F)cc2)n1C)CC3 +COc1cccc(Nc2nc(-c3cccc4onc(C)c34)nc3c2cnn3C)c1 +N#Cc1ccc(NC(=O)N2CCC(O)c3ccc(C=O)nc32)nc1 +CN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4nnc5ccc(-c6ccc(F)cc6)nn45)c3n2)CC1 +O=C(NCc1ccc(Cc2c[nH]cn2)cc1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC1(C)Cc2c(N3CCOCC3)nc3sc4c(NCCN5CCOCC5)ncnc4c3c2C1 +CC1=C([N+](=O)[O-])C(c2ccccc2)C2=C(O)c3ccccc3C2=N1 +Cc1ccc(-c2cc(F)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)c2ccccc2c1 +CCCC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 +CC(C(=O)O)c1ccc(-c2cccc(OC(=O)NCC3CCCCC3)c2)c(F)c1 +CCN(c1nc(C)cc(-c2ccccc2Br)n1)c1ccc(C(C)C)cc1Br +CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)CC3CCCCC3)C2)nc1C +CC(OCc1cc(F)cc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccc(F)cc2)c1)C(F)(F)F +Cc1ccc(-c2cc(C(=O)NC(C)c3cnccn3)cc(-n3c(=O)oc4ccccc43)c2)nc1 +O=C(CCc1ccccc1)N(Cc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +N#Cc1ccccc1Cn1c(N2CCCC(N)C2)nc(-c2ccccc2)cc1=O +Cc1nc(C(CC2CC2)N(C)C(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)no1 +NC1CCCN(c2cccc(-c3n[nH]c4cnc(-c5cncc(F)c5)cc34)n2)C1 +COc1ccc2c(c1)-c1nc(-c3ccc(C4(N)CC(C)(O)C4)cc3)c(-c3ccccc3)n1CO2 +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1OC1COCCC12 +CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)c3ccc(Cl)s3)C2)nc1C +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc(-c2ncccc2C(F)(F)F)nc1O +COC(=O)c1cccc(-c2cnc(C(=O)C3CCc4cc(OCc5ccccc5)ccc4C3)o2)n1 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2ccc3c(c2)OCO3)cc1 +COCCNC(=O)c1ccc(Nc2ncc(C(F)(F)F)c(Oc3cccc4c3C(=O)N(C)C4)n2)c(C)c1 +Cc1n[nH]c(O)c1C(c1ccc(N(C)C)c(Br)c1)c1c(C)n[nH]c1O +CN(C)c1ccc(C(=O)NCC=CCN2CCN(c3ccccc3OCCF)CC2)cc1 +CC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 +Fc1ccc2sc3c(c2c1)CCN(Cc1cncc2ccccc12)C3 +Cc1cnc(NC(=O)C(COC(C)CO)Oc2ncnc3c2cnn3-c2c(Cl)cccc2C#N)cn1 +CCN(CC)CCCn1ccc2ccc(NC(=N)c3cccs3)cc21 +COc1cn(C)c(=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nn1C)C2=O +Cc1ccc(Cc2cc(C3SC(CO)C(O)C(O)C3O)ccc2Cl)cc1 +Cc1cc(C)cc(-c2[nH]c3ccc(C(C)(C)C(=O)N4CCCC4)cc3c2CCNCCCCc2cccnc2)c1 +Cc1cc(C(=O)N2c3cccc(O)c3NC3=C(C(=O)CC(C)(C)C3)C2c2ccc(OCc3ccccc3)cc2F)no1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(NC3CCCCC3N(C)S(C)(=O)=O)n1)C(C)(C)CN2 +O=C(C=Cc1ccc2c(c1)OC(C(=O)O)C(c1ccc(O)c(O)c1)O2)OC=Cc1ccc(O)c(O)c1 +CC(C)(C)c1ccc(C(=O)NCCOc2ccccc2F)cc1 +CCC(C)C(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccc(OC(C)C)cc2)cc1 +Cc1nc(-c2cccc(C(=O)Nc3cccc(CNc4ncnc5c(C(N)=O)cccc45)c3)c2)no1 +CNC1CCC(c2ccc(Cl)c(Cl)c2)c2ccc(CNS(C)(=O)=O)cc21 +CC1=CC(=O)C(O)C2(C)C1CC1OC(=O)C(OC(=O)C(C)CO)C3C(C)C(O)C4(O)OCC13C42 +COc1ccc(C(=O)CNC(=O)CCn2c3c(c(=O)[nH]c2=O)CCCC3)cc1 +O=S(=O)(NC1C2CCN(CC2)C1Cc1cccnc1)c1ccccc1 +OC1(c2ccc(F)cc2)CCN(Cc2c[nH]c3ccccc23)CC1 +COc1ccc(Cl)cc1N1CCN(CCn2c(=O)[nH]c3c([nH]c4ccccc43)c2=O)CC1 +Cc1nc(-c2cn3c(n2)-c2cnc(-c4cnn(C)c4C4CCCN(C(C)C)C4)cc2OCC3)n(C(C)C)n1 +N=C(N)N1CCC(C(=O)NCC(=O)N2CCN(CC(=O)O)C(=O)C2CC(=O)O)CC1 +O=C(Nc1ccc(S(=O)(=O)O)cc1)C(CS)Cc1ccc(-c2ccccc2)cc1 +COCCN(C)c1nc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(C(N)=O)cc3)CC2)nc2ccsc12 +CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(C2=C(c3nn[nH]n3)CCC2)cc1 +CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1ccc(Cl)cc1 +CC(Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)c1ccc(C#N)cc1F)CC2)c1ccc(C(F)(F)F)cc1 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCOCC4)cc3)cc12 +CCN(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)c1ccccc1C(F)(F)F +COc1ccc(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(N4CCN(C)CC4)c(F)c3)n2)c(OC)c1 +CCc1ccc(S(=O)(=O)N2CCCC(O)(c3ccccc3)CC2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)OC3CCOCC3)c2cn1)c1ccc(F)cc1 +COc1ccccc1N1CCN(CCn2nc(-n3ccc4ccccc43)ccc2=O)CC1 +Cc1ccc(-n2cc3c(n2)c(=O)[nH]c2ccccc23)cc1 +CN1CCC=C(c2nsnc2OCCCCCCCC2CCN(CCCN3C(=O)CCc4ccccc43)CC2)C1 +COc1ccc(C=C2CS(=O)(=O)CC(=Cc3ccc(OC)c(OC)c3)C2=O)cc1OC +Cc1ccc(NC(=O)C2CSc3c(C4CC4)c(Cc4cccc(C)c4C)c(N)c(=O)n32)cc1 +COc1ccc(CCn2c(=O)c3ccccc3c3nc4ccc(NCCCn5ccnc5)cn4c32)cc1 +CCCCc1nn(CCCCCC(=O)OCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN1CCN(c2ccc(NC(=O)c3cc(-c4ccc5c(c4)OCO5)cnc3O)cc2)CC1 +O=C(O)CC(Cc1ccccc1)NC(=O)C(CC(=O)NO)Cc1ccccc1 +Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)(F)F)cc2)s1 +Cc1cc(NCC(N)c2ccccn2)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +Nc1ncc(C(=O)N2CCOCC2)cc1-c1ccc(C(=O)NC(CO)c2cc(F)cc(Br)c2)c(F)c1 +CC(C)(C)NC(=O)c1cccc(-c2cc3nccc(-c4ccc(OC(F)F)c(OCC5CC5)c4)n3n2)c1 +CC(C)CC(C)NC(=O)CNC(=O)C(COC(C)(C)C)NC(=O)C(N)Cc1ccc(O)cc1 +COCCOc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OCCOC +CCN(CC)c1ncc(N(CC)C(=O)Nc2ccccc2)c(NC(Cc2ccc(OC(=O)N3CCCC3)cc2)C(=O)O)n1 +COc1ccc2ccc(S(=O)(=O)N(CC(=O)O)C3CCN(Cc4cccc(C(=N)N)c4)C3=O)cc2c1 +O=c1oc2ccc(Cl)cc2c2nc(-c3c(F)cccc3F)nn12 +Cc1ccccc1Nc1ncnn2ccc(CN3CCC(N)CC3)c12 +N=C1NC(c2ccccc2Br)CC2CCC(CCc3ccccc3)N12 +CC(=NNc1nc(-c2ccccc2)c(C)s1)c1ccccn1 +O=C(NC1CCCC1)NC(Cc1ccccc1)(c1cc(F)cc(C(F)(F)F)c1)c1ccc(Cl)cn1 +COc1ccc(C(=O)NC(=O)Nc2ccc3c(c2)NC(=O)C3=Cc2ccc(O)cc2)cc1 +CC(C)CC(NC(=O)Cc1ccccc1)C(=O)NC(CC1CCCCC1)C(O)C(=O)c1ccccc1 +CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCCC(F)(F)C4)cc3c2)CC1 +Cc1ccc(CNCC2CC3(c4ccccc4)CCN2C3)cc1 +Cn1cc(-c2nc(-c3cn(C)c4ncccc34)cs2)c2ccccc21 +FC(F)(F)Oc1ccc(Nc2cc(Nc3nccn3-c3cc(Br)cc(C(F)(F)F)c3)ncn2)cc1 +COc1cc2oc(-c3cccc(OCCCCN4CCN(C)CC4)c3)cc(=O)c2c(OC)c1OC +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)NC1CCN(C(=O)Oc2ccccc2)CC1 +CCOCCC1(Oc2ccc(Oc3cccc(F)c3)cc2)C(=O)NC(=O)NC1=O +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1c(F)cccc1F)C(C)C +COc1cc(C2c3cc4c(cc3C(OC(=O)c3cnc5ccccc5n3)C3COC(=O)C23)OCO4)cc(OC)c1OC +O=S(=O)(c1cccc(F)c1)c1cc(F)c2c(c1)CCCC2CNCCO +COc1cc(-c2nc(-c3cc(C)nc(C(F)F)c3)c3n2CC(CF)OCC3)ccc1Cl +CC1(C)C(=O)NC(=O)c2c1ccc1[nH]c(Nc3c(Cl)cccc3Cl)nc21 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)Cn1ccnc1)C2 +Cc1cc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NC2CCN(C)CC2(C)C)c(C)cc1Cl +COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(O)cc3)oc12 +O=C(Nc1ccc(C(=O)CCl)cc1)Nc1ccc(-c2nc(N3CCOCC3)c3cccnc3n2)cc1 +CN1CCN(c2nc(Nc3ccccc3)nc(Nc3cccc(Nc4ccnc5cc(Cl)ccc45)c3)n2)CC1 +CCOc1ncccc1C1C(C(=O)C2CCCC2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +CC1(n2c(-c3cccnc3)nc3ccc(F)cc32)CC1 +C=CCOC(=O)N1CCCC(C(=O)N2CCN(C(=O)CCc3nc4ccccc4c(=O)[nH]3)CC2)C1 +CCCCN(CCCC)C(=O)C1OC(C(=O)O)=CC(N)C1NC(C)=O +CN(CCO)c1ccc(-c2nc3c(C(=O)NC4CCCNC4)ccnc3[nH]2)s1 +Cc1c(C(=O)NCCCCCCCCNCc2ccccc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +NC(=O)c1ccc(-n2c3c(c4ccccc42)C(=O)CCC3)cc1NC1CCC(O)CC1 +CSc1ccccc1C=CS(=O)(=O)Nc1ccccc1S(N)(=O)=O +Fc1ccc(OCCN2CCC(c3ccc(F)cc3)CC2)cc1 +CS(=O)(=O)c1ccc2c(c1)CCN2c1ncnc2c(C3CCN(c4ncc(F)cn4)CC3)coc12 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3C(F)(F)F)nc12)N1CCC(O)C1 +C#CCN(C)CC(=C)c1cccc(OCc2cccc(OC)c2)c1 +Cc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 +O=C(O)CN(C1(c2ccc(-c3ccccc3OC(F)(F)F)cc2)CCC1)S(=O)(=O)c1ccc(OC(F)F)cc1 +Cc1nnc2sc(C(=O)NC3CN(c4ccc(S(=O)(=O)C(F)(F)F)cc4)C3)c(N)c2c1C 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+O=C(C=Cc1ccc2c(c1)CN(Cc1ccccc1)C2=O)NO +O=C(C=Cc1ccccc1)Nc1nc(-c2ccncc2)cs1 +COC(=O)CNc1nc(-c2ccccc2F)nc2ccccc12 +CCc1cc(-c2ccc(C(N)=O)c(NC(C)(C)C)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c2n1 +Nc1ccn(C2OC(COP(=O)(O)OC(C(=O)Nc3ccccc3)P(=O)(O)O)C(O)C2O)c(=O)n1 +COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cccnc1OC)C2 +O=C1c2ccc(NC3=NCCN3)cc2C(=O)c2ccc(NC3=NCCN3)cc21 +CCCN1CCOc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc21 +COc1ccc(-c2cc3ccccc3nc2C=CC(=O)c2ccsc2)cc1 +CCCNC(=S)Nc1cc(C=CC(=O)NO)ccc1OCCN(CC)CC +Oc1ccc(C23CCC(C2)N(CCc2ccccc2)CC3)cc1 +NC(=O)c1ccc2c(c1)CCOC2CCN1CC=C(c2noc3cc(F)ccc23)CC1 +CC(C)N(C)c1cc(-c2csc(N(C)C(=O)c3ccc(F)cc3)n2)ncn1 +Nc1ccc(S(=O)(=O)N2CCc3cc(O)ccc3C2C(=O)NO)cc1 +O=C(NCC(=O)N1CCC(NC2CCC(O)(c3ccc(-c4cnccn4)cn3)CC2)C1)c1cccc(C(F)(F)F)c1 +COc1ccncc1N1C(=O)c2c(Cl)ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C1=O +CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)n5cccn5)c4)c(C)nc23)ccn1 +CC(C)(C)C1CCN(c2cccc(Nc3cc(-c4cccc(C(N)=O)c4)nn4ccnc34)n2)C1 +O=C(C=Cc1cccn(CCCc2cccc(Cl)c2)c1=O)NO +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2cc(C)nc(NCC(C)(C)C)c2n1 +Cc1cc(C)[n+](CC(=O)Oc2ccc3nc(S(N)(=O)=O)sc3c2)c(C)c1 +COC(=O)CNC(=O)C1CC(NC(=O)c2cc(C3CC3)nn2C)CN1C(=O)c1coc2ccccc12 +CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NCCN(C)C)c4)c(C)nc23)ccn1 +CNC(=O)Oc1cccc(CN(C)CCCCCCCCOc2ccc3c(=O)c4ccccc4oc3c2)c1 +CC(C)OC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 +CCCCc1nn(-c2cc(Cl)ccc2Cl)c(C(=O)O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCN(c3ccc(C#N)cc3)CC2)c2ccc(C)c(Cl)c2)CC1 +CCC1CC(CC)c2cc3c(C(F)(F)F)cc(=O)oc3cc2N1 +COc1ccc(Cn2c(=O)c(NCCN3CCOCC3)nc3ccc(-c4ccc(F)c(F)c4)nc32)cc1 +CNC(=O)C(Cc1ccccc1)NC(=O)c1c(C)n(CCN2CCOCC2)c2c(OC)cccc12 +CN(C)C(=O)c1ccc(Nc2nc3cccc(-c4ccc(C(=O)N5CCOCC5)cc4)c3o2)cc1 +COc1ccc(CN(C(CC(C)C)C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1ccnc(N2CCOC(CO)C2)c1 +Cc1c(C(=O)Nc2ccnc(Cl)n2)nn(C)c1-c1ccc(F)cc1 +CNCCNC(=O)C1C(C(=O)NCc2nc(C(C)=O)cs2)C2C=CC1C21CC1 +NC(=O)c1ccc2[nH]c(-c3ccc(Cc4ccc5ccccc5c4)cc3)nc2c1 +CC(C)CC(NC(c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(F)(F)F)C(=O)NC(C)(C)C#N +CC(Oc1cc(-c2nc(-c3ccc(CN(C)C)cc3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F +O=C(NCC1(O)CCCCCC1)c1cc(-c2ccccn2)ccc1Cl +Nc1cccc(C(=O)NN=C2c3cc(Cl)ccc3C(=O)C3C=CC=CC23)c1 +C=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2n1 +CC(C)(O)COc1ccc2c(c1)c(NC(=O)N1C(C(=O)NCc3cccc(Cl)c3F)CC3CC31)cn2C(N)=O +CC(C)n1nc(Cc2cc(F)cc(F)c2)c2c(N)ncnc21 +COc1cc(CN=C(S)NCCc2ccc(Cl)cc2)ccc1OCCN +Cc1[nH]c2ccccc2c1C=NNc1nc(Nc2ccccc2)nc(N2CCOCC2)n1 +CCCCc1ccc(C2=NN(S(=O)(=O)c3ccc(CCCC)cc3)CCC2)cc1 +COCC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cn3)c2)c2cncnc21 +Cc1ccc(C2C3=C(CC(C)(C)CC3=O)Nc3nc4c(c(N)c32)CCCC4)cc1 +CC1(CCC(=O)NC(Cn2cncn2)CP(=O)(O)O)SCCS1 +COCC1CCCN1c1cc(Nc2nccs2)nc(-n2nc(C)cc2C)n1 +CCCN(CCCCOc1ccc2ccnn2c1)C1CCc2c(O)cccc2C1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(F)c(C(F)(F)F)c4)cn3CCN3CCCCC3)CC2)c1-c1cccc(F)c1 +COc1cccc2c1ncc1c(=O)n(C(C)C)c(=O)n(C3CCCC3)c12 +CC(C)S(=O)(=O)c1c(O)n(Cc2ccc(F)c(F)c2)c(=O)c2ccc(Cl)cc12 +C=C(c1ccccc1)c1ccc2cccc(-c3cc4c([nH]3)CCNC4=O)c2n1 +COc1ccc(CNc2nnc(N3CCC(=O)CC3)c3ccc(C#N)cc23)cc1Cl +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(NCC(C)(C)O)c2n1 +CN(C)CCNC(=O)c1cc(Cl)cc2nc3ccccc3nc12 +CCC(c1ccncc1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +O=C(CCc1cn(Cc2ccccc2)c2ccc(F)cc12)Nc1ccncc1 +COC(=O)c1cc(-c2ccc(C=C3SC(=O)N(CCC(=O)O)C3=O)s2)ccc1O +COc1cc2cc[n+](C)c(Cc3cccc(Cc4c5c(OC)c(OC)c(OC)cc5cc[n+]4C)c3)c2c(OC)c1OC +CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1Br +CC(C)n1cnc2c(Nc3cccc(-c4ncccn4)c3)nc(Cl)nc21 +CSc1nn2cc(-c3cc4c(OCc5ccc(F)cc5)cccc4o3)nc2s1 +CCC(C)C(NS(=O)(=O)c1ccc(Br)c(Br)c1)C(=O)NC(Cc1cscn1)C(=O)NO +CC(c1ccn(-c2ccc(C(F)(F)F)cc2)c1)N1CCC(NC(=O)COc2cccc(Cl)c2)CC1 +CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1cccc(Cl)c1 +CCCCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 +COc1ccc(CC(C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O +CC(C)(O)C1CCC(Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1 +NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1ccccc1Cl +COc1cc(S(=O)(=O)c2ccccc2F)cc2c3c(n(C)c12)CC1CCC3N1 +O=C(Nc1cc(F)ccc1B(O)O)c1ccc(Oc2ccc(C(F)(F)F)cc2)nc1 +CCC(C)C(NS(=O)(=O)c1cc(Br)c(Br)s1)C(=O)NC(CNC(=O)OCc1ccccc1)C(=O)NO +O=C(O)c1cn2c3c(nc(O)c2n1)-c1ccccc1C3 +CN(C)c1ccc(C(=O)C=Cc2ccc(O)c(O)c2)cc1 +N#Cc1ccc(C(=O)Nc2ccc(C3CCNC3)cc2)cc1 +COc1ccc2c(CC3NC(=O)C4CCCN4C3=O)c(CC=C(C)C)[nH]c2c1 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(C4(O)CCOC4)ccc3Cl)nnc12 +CC1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4F)cc32)C(CN2CCOC2=O)CN1 +N=C(N)NCCCCC1CC(C(=O)NCC(NS(=O)(=O)c2cc(Cl)sc2Cl)C(=O)O)=NO1 +Nc1nc(Cc2ccc(Br)cc2)cc(C2CCN(C(=O)c3ccc4c(c3)OCO4)CC2)n1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1OCC(C)(CN)CO1 +CC(C)C(CC(=O)NCCn1c(-c2cccnc2)nc2ccccc21)C(=O)NC(C=O)CC(=O)O +Cc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2)nc1-c1ccc(F)c(C(F)(F)F)c1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cncc(N2CCOCC2)n1 +Cc1cc(Nc2cc(C)c(C#N)c(SCCCCCCN)n2)n[nH]1 +Cc1c(COCC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCNC(=O)OC1=C(c2ccccc2)Oc2ccccc2-n2cccc21 +CCn1cc(-c2ccnc3[nH]ccc23)c(-c2cccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c2)n1 +CCNC(=O)c1ccc(Oc2ccc(Cc3nnn[nH]3)cc2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 +CC(C)Oc1nccc2[nH]nc(-c3cc(C(=O)N4CCCCC4)n(C(C)C)c3)c12 +CCOc1nc2ccc(C(O)(c3ccc(OC)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 +COc1ccc(NC(=O)Nc2ccc(Cl)cc2C(F)(F)F)cc1-c1c(Br)cnn1C +COc1ccc2cc3[n+](cc2c1NCc1ccccc1)CCc1cc2c(cc1-3)OCO2 +COc1ccc(-c2cnc(NC(=O)N3CCC4(CC3)OC(=O)c3ccccc34)nc2)cc1 +COc1ccccc1C=CC(=O)NC(=S)Nc1ccc(S(=O)(=O)N(Cc2ccncc2)c2ccccc2)cc1 +Cc1cccc(N2CCN(C(=O)Nc3ccc(O)cc3)CC2)c1 +CCOc1ccc(Cc2cc(C34OCC(Sc5ccccn5)(O3)C(O)C(O)C4O)ccc2Cl)cc1 +N#Cc1ccc(N2C(=O)C3NN=C(C(=O)c4ccc5ccccc5n4)C3C2=O)cc1 +COc1ccc(S(=O)(=O)c2n[nH]c3ccc(NC4CCNCC4)cc23)cc1 +O=C(NCCCCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)OCc1ccccc1 +CC(C)C(CO)NCc1nc(-c2cc(C(F)(F)F)ccc2F)ccc1F +Cc1ccc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCN(C)CC3)nc12 +Cc1cccc(N2CCN(CCCNC(=NC#N)c3ccncc3)CC2)c1C +CN(c1ncnc2c(-c3ccc(S(C)(=O)=O)cc3)csc12)C1CCN(C(=O)C2CC2)CC1 +Cc1cc(N(C)C)nc2ccc(NC(=O)COc3ccc(C(F)(F)F)cc3)cc12 +Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(S(C)(=O)=O)cc2)c[n+]1[O-] +CCN(Cc1cc(S(C)(=O)=O)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 +Nc1nnc(-c2ccc3[nH]cc(-c4cncc(NC5CCCC5)n4)c3c2)s1 +CN1CCc2cc(F)cc3c2C1Cc1ccc(O)c(O)c1-3 +COc1ccc(-c2cc(Cl)c3c(N)ncnn23)cc1N1CCN(C(C)=O)C(C)(C)C1=O +O=C(O)C(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C1OCOC1C(=O)Nc1c(Cl)cncc1Cl +COc1cccc(-c2cc(COc3cccnc3)ccc2C(=O)NC(CCSC)C(=O)O)c1 +C=CCOC(=O)Nc1ccn(C2OC(CO)C(O)C2(F)F)c(=O)n1 +CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2Cc2csc(Br)c2)n1Cc1ccc(C(=O)OC)cc1 +O=C(NCCCCCCS)c1cc(-c2ccc(F)cc2)nn1CCO +Cc1[nH]cnc1C1CCN(c2ncncc2-c2ccc(F)c(Cl)c2)CC1 +COc1ccc(-n2nc(SC)c3ccc(N4CCNCC4)cc32)cc1 +c1cc2c3cnc(Nc4ccc(N5CCCC5)nn4)nc3n(C3CCCC3)c2cn1 +Cc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2C(N)=O)c1NS(N)(=O)=O +CN(c1c(F)cc(C#N)cc1F)C1CCN(c2ncnc3[nH]ccc23)C1 +CC1CCCC(COC(=O)NCCCn2ccnc2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCOC(=O)C(C(=O)OC1CC2C3OC3C(C1)[N+]2(C)C)c1ccccc1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(Cc1ccc3c(c1)OCCO3)CC2 +CNCc1cn(S(=O)(=O)c2cc(C)ccn2)c(-c2cccnc2F)c1F +N#Cc1cccc(C23CCC(N(CCN4CCC(O)C4)C(=O)Nc4ccc(F)c(C(F)(F)F)c4)CC2C3)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OC4CCC4)n3)C2)cc1 +NC(Cc1ccc(-c2ccccn2)cc1)C(=O)N1CCSC1 +COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)NCCO +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1cccc(F)c1)CC2 +Cc1cc(F)cnc1C(=O)Nc1ccc(F)c(C2(C)N=C(N)C(C)(F)CC2(F)F)c1 +NC1=NC(c2cc(NC(=O)c3ccc(Br)cn3)ccc2F)(C(F)F)C2CC2O1 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3ccc(C(C)C)cc3)cc12 +CCS(=O)(=O)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1C(C)OC +Cc1c(CN(C)c2cccc3c2CCCC3)cnc2nc(N)nc(N)c12 +COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1B1OC(C)(C)C(C)(C)O1 +CC(C)Oc1ccc2[nH]nc(-c3ccnc(N4CCN(C)C(=O)C4)c3)c2c1 +CN1CCN(Cc2ccccc2S(=O)(=O)c2csc(S(N)(=O)=O)c2)CC1 +Cc1cccc(NC(=O)NC(C[S+]([O-])Cc2ccccc2)C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CCN1Cc2cc(-c3nnn(-c4cccnc4F)c3C)ccc2C1=O +CN1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1 +COc1ccc(-c2ccn(-c3ccc4c5c(n(C)c4c3)CCNC5)c(=O)c2)c(C)c1 +O=C(O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1ccc(F)cc21 +COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c(-c3ccc(OC)c(O)c3)[nH]c2c1 +COc1cc(C(=NO)c2noc(-c3ccc(C)cc3)n2)cc(OC)c1OC +Cc1cc(N2CCCN(Cc3csc(-c4ccccc4)n3)CC2)c2nccn2c1 +COc1ccc2c(c1)C=C(C1CC3CN(c4ccccc4)C(=O)C34CCCN14)CO2 +CCOc1ccc(-n2c(C)c(C(C)=O)c3cc(O)ccc32)cc1 +CCCS(=O)(=O)N1CCN(C2(CNC(=O)c3ccc(Cl)cc3Cl)CCOCC2)CC1 +CCOC(=O)CCS(=O)(=O)Cc1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)cc1 +CC12CC(CCCCOS(C)(=O)=O)C3c4ccc(O)cc4CCC3C1CCC2O +O=C(Nc1ccc(Br)cc1F)N1CCNCC1COc1cccnc1 +Cc1ccc(CN2C3CCC2CC(Oc2cccc(C(N)=O)c2)C3)cc1 +CC(C)(F)CCNc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +CCCCc1nc(C)n(Cc2occc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(C)CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cccc(-c3ccccc3)n2)CC1 +Clc1cccc(C2C(NCc3ccccc3Cl)C3CCN2CC3)c1 +Nc1nccc(Nc2ccc3[nH]nc(-c4ccc[nH]4)c3c2)n1 +N#Cc1ccc(CSc2nnc(-c3ccc4c(c3)OCO4)o2)cc1 +COc1cc(C#Cc2nn(C3CN(C(=O)C=CCN(C)C(C)C)C3)c3ncnc(N)c23)cc(OC)c1 +O=C(O)CON=C(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +CNC(=O)N1CCCC(C(C)Nc2nccc(-n3cnc4ccccc43)n2)C1 +O=c1c(-n2ccnn2)c[nH]n1-c1cc(C2CC2)ncn1 +CCCCCOc1c(O)cc(Br)c2c1CN1CCc3cc(OC)c(O)cc3C1C2 +O=C(C1CCOC1)N1CCC(CNc2nc3c(s2)CCCc2ccc(F)cc2-3)CC1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCCOc4cccc(Cl)c4)nc23)N1 +NC1=NC(c2cccc(NC(=O)c3ccc(C(F)(F)F)cn3)c2)(C(F)F)COC1 +O=C(NC1CCOC1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +Cn1ccc(-c2cc3c(-c4cccc(N5CCNCC5)n4)n[nH]c3cn2)cc1=O +Cc1cnc(Nc2cccc3c2OCO3)nc1-c1c[nH]c(C(=O)NC(CO)c2cccc(Cl)c2)c1 +COc1ccc(C(=O)Nc2ncc(-c3ccc(C(=O)O)cc3OCCc3ccccc3)s2)cc1 +Cn1ncc(C(=O)N2CCC2)c1C(=O)NCCc1nc(-c2ccccc2)nn1CC1CC1 +O=Cc1c(O)ccc2nc(-c3ccc(C(=O)NCCN4CCOCC4)cc3)[nH]c12 +Nc1nc(NCc2ccccc2-c2ccccc2)nc(-c2ccc(CC(N)C(=O)O)cc2)n1 +COc1cccc(-c2ccc(S(=O)(=O)Nc3cc(N4CC(C)NC(C)C4)ccc3OC)cc2)c1 +CC12CCC(=O)CC1CCC1C2CCC2(C)C1CCC21CCCO1 +CNS(=O)(=O)c1cccc(Oc2cccc(-c3c(C(C)C)nc4c(Cl)cccn34)c2)c1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1cc(C(F)(F)F)ccn1 +CCOc1ccc(C(C)=O)cc1CSc1nc2cc(F)ccc2n1CC(=O)O +Cc1cnn(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C)n2)c1 +CCC(C)n1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)c(-c2ccnc(C(F)(F)F)c2)c1C +CN(C)CC(C)(C)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3cnccn23)n1 +CN1CCN(Cc2ccc(Nc3ncc(Cl)c(-c4ccc(F)cc4S(=O)(=O)N(C)C)n3)cc2)CC1 +C=C(C)C1CCC2(C(=O)O)CCC3(C)C(CCC4C5(C)CCC6(OCCO6)C(C)(C)C5CCC43C)C12 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCC1CCCCC1)CC2 +COc1cc2c(N)nc(N3CCN(C(=O)CC(N)c4ccc(C(F)(F)F)cc4)CC3C)nc2c(F)c1OC +Clc1ccccc1Nc1cc2[nH]c(-c3cn[nH]c3)cc2cn1 +CCCNc1nccc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c1F +COc1ccccc1N1CCN(CCCC2CCCc3c(OC)cccc32)CC1 +Cc1ccccc1-c1cc(C(OCc2cccc(C#N)c2)c2cncn2C)ccc1C#N +COc1ccc(CCO)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(CCCO)cc2)c1 +CC(C)CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(N)CC1 +Cc1cc(-n2ncc(=O)[nH]c2=O)cc(C)c1Oc1ccc(O)c(Cc2ccc(F)cc2)c1 +COc1cc(-c2cn(C3CCC4CCCCC4N(Cc4ccccc4)C3=O)nn2)ccc1-n1cnc(C)c1 +Cc1c(OCC(=O)O)ccc(F)c1NCc1cc(-c2cccc(F)c2)ccc1F +O=C1c2ccc(C#Cc3ccccc3)cc2C(=O)N1CCc1ccccn1 +CC(CO)Nc1cc(NS(=O)(=O)C(F)(F)F)nc(SCc2ccccc2)n1 +Cc1ccc(-c2csc(NC(=O)Cc3cccc4c3c(=O)n(C)c(=O)n4C)n2)cc1 +CCN(CC)c1ccc(NC(=O)CN2C(=O)CSc3ncccc32)c(C)c1 +COc1ccc2sc(CNc3nncc(-c4cc(-c5ccn[nH]5)ccc4Cl)n3)nc2c1 +Cc1cc(-c2nnc3n2CCCCC3)c(C)n1-c1ccc([N+](=O)[O-])cc1 +COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCOCC1 +O=C(CN1CCCCC1)Nc1ccc2nc3n(c(=O)c2c1)CCc1c-3[nH]c2ccccc12 +CC(C)(C)c1nc(N2CCN(CCCCn3ccc(N4CCC4)nc3=O)CC2)cc(C(F)(F)F)n1 +COc1ccc(S(=O)(=O)N(CCn2cc(CCCF)nn2)C(C(=O)NO)C(C)C)cc1 +COc1ccc(C2c3[nH]c4ccccc4c3CC3C(=O)N(CCc4ccccn4)C(=O)N32)cc1 +Cc1ncnc(C)c1-c1ccc(Oc2nccc3[nH]ccc23)cc1F +Nc1cc(NC(=O)c2cccc(Cl)c2)cc(Oc2cccnc2)c1 +CCCNc1nccc(C2CCCN(CCc3c[nH]c4ccccc34)C2)n1 +O=C1OCC(Cc2ccccc2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc1C +O=C(O)C1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +CCOc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C)c3)cn2CCN2CCCC2)CC1 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccc(C#N)cc3)n2)CC1 +CCCC(=O)c1cnc(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)s3)CC2)c(Cl)c1 +CCCNC1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2C1C +CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3cc(=O)n(C)c(=O)n3C)c2)CC1 +C=C(C)COCn1c(C(F)c2cc(C)cc(C)c2)c(CC)c(=O)[nH]c1=O +COc1cccc2c1c(NS(=O)(=O)c1ccc(C)c(F)c1)nn2Cc1cccc(CNC(=O)C(C)(C)O)c1 +CC(C)Cc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 +CC(C)NC(=O)C1=CC(C)(C)Oc2ccc([N+](=O)[O-])cc21 +CCCCCC(CC(=O)NO)C(=O)NC1CCCCN(CC(=O)OC)C1=O +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc4c(c3)c(N)nn4CCN(C)C)NC(=O)NC1=O)C2 +COc1ccc(NC(=O)Oc2cccc3ccc(C)nc23)cc1 +C=CC1OC2(CCC3=Cc4c(cnn4-c4ccc(F)cc4)CC32C)OC1C=C +CSc1nc(NCCc2ccccc2)c2cnn(CC(Cl)c3ccc(Cl)cc3)c2n1 +Cc1cccnc1-c1cc(N2CCC(C(=O)N3CCCCC3CO)CC2)ncc1Cl +CN1CCC(Oc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3n2)CC1 +CCc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +CC(c1ccc(Cl)cc1)N1Cc2cncn2C(CC(O)c2ccccc2)S1(=O)=O +CCN(CC)CCSc1nc(-c2cc(OC)c(OC)cc2Cl)c2c(C#N)c[nH]c2n1 +O=C(CCN1CCN(c2ccccc2)CC1)NN=Cc1ccc([N+](=O)[O-])o1 +COc1cccc2c1ccc1nc3cccc(C(=O)NC(CN(C)C)C(C)C)c3nc12 +O=C1C(=Cc2ccccc2F)CS(=O)(=O)CC1=Cc1ccccc1F +Cc1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOCC4)N3)n2)cc1 +CCCc1cc2cc(C(=O)C3CCC(OC)CC3)ccc2nc1C +NC(=O)c1ccc2[nH]c(-c3ccc(C(O)c4ccccc4)cc3)nc2c1 +CC1CCC(C)N1C(=O)c1ccc(-c2ccc(OCCCN3CCC(O)C3)cc2)cc1 +CN1C(=O)CC(c2ccccc2)C1C(O)c1ccc(S(=O)(=O)N2CCOCC2)s1 +COc1cc(Nc2nc3n(n2)CCC(O)N3Cc2ccccc2)ccc1-n1cnc(C)c1 +CC(C)Oc1ncc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cc1C(F)(F)F +CCNC(=O)c1cc2c(N3CCOCC3C)ccnc2[nH]1 +Nc1nc(N)c2nc(CNc3c(Cl)cc(C(=O)NC(CCCNC(=O)c4ccccc4C(=O)O)C(=O)O)cc3Cl)cnc2n1 +CCCc1cc(C(=O)NC(Cc2ccccc2)C(O)CNCc2cccc(C(F)(F)F)c2)cc(N2CCCCS2(=O)=O)c1 +Cc1nn(C)c(-c2ccc(F)cc2F)c1-c1ccc2c(c1)NC(=O)CO2 +O=C(O)CCc1c(C=C2C(=O)Nc3ccc(C(=O)O)cc32)[nH]c2c1CCCC2 +CCCCOc1cc(-c2cc3c(O)nc(C)nc3cc2C(C)C)ccc1Cl +COc1cc(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)C23C)c2ccccc2c1 +Cn1c(Cl)nc(C(=O)N2CCC2)c1C(=O)NCCc1nc2ccccc2n1C +C=CCC1CN(C)CCC1(OC(=O)CC)c1cccc(O)c1 +O=C(Nc1ccc(C(=O)N2CCOCC2)cc1)N1Cc2ccncc2C1 +COc1ccc2c(c1)C1(CCNCC1)C(=O)N2Cc1cc2cnc(C#N)nc2n1CC(C)(C)C +CCCC(=O)c1sc2cnccc2c1Nc1ccc2c(c1)CCC2=NO +CS(=O)(=O)N1CCC(C(O)c2cncnc2Cc2ccccc2)CC1 +Cn1cc(C2=C(c3nc(N4CCNCC4)nc4ccccc34)C(=O)NC2=O)c2ccccc21 +COc1cc(Nc2ncnc3ccc(-c4ccc(CN5CC6C(CO)C6C5)cc4)cc23)ccc1Oc1ccccc1 +CC(C)CC(C(N)=O)N(Cc1ccc(CCl)cc1)S(=O)(=O)c1ccc(Cl)cc1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(c2ccc(F)cc2)CCCC1 +CCC(CC)(NC(=O)c1ccc(C2CC2)c(S(=O)(=O)CC(C)C)n1)C(=O)NC +CC1CCC(Cn2c(N3CCOC4CCCC43)nc3cc(C(=O)NS(C)(=O)=O)nc(-c4cncc(Cl)c4)c32)CC1 +Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1 +CC(=O)c1cn(CC(=O)N2C(C(=O)Nc3cccc(Br)n3)CC3CC32)c2ncccc12 +CCNC1CCc2cc(OC)c(OC)c(OC)c2-c2ccc(OC)c(=O)cc21 +CC(C)C(O)CC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2ccccc2[nH]1 +Cn1ncc(OC(F)F)c(-c2ccc(CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)c1=O +COCCN1CCN(C(=O)c2cc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3)cs2)CC1 +COc1cscc1C(=O)NC1C(CC=CCCCC(=O)O)CC2CC1C2(C)C 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+CC(C)(C)OC(=O)N1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)CC1 +O=C(Nc1ccc(C(=O)N2CCc3c([nH]c4ccccc34)C2)cc1)N1Cc2ccccc2C1 +COc1n[nH]c2cc(NC(=O)NC(c3ccc(F)c(C)c3)C(C)(C)O)nc(CO)c12 +O=C1c2cnc3[nH]ccc3c2N(C2CCC(CNCC(F)(F)F)CC2)CN1CC1CC1 +O=c1ncn2nc(Sc3ccc(F)cc3)ccc2c1-c1c(Cl)cccc1Cl +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCCC23CCCN2CCC3)cc1F +Cc1c(N(Cc2cc3cccc(Cl)c3s2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +COc1ccc(S(=O)(=O)N2CC(C(=O)NCCCn3ccnc3)c3ccccc32)c2ccccc12 +CC1CCN(C(=O)C(CCn2cccc2C#N)NS(=O)(=O)c2ccc3[nH]ccc3c2)CC1 +COc1ccc(N(C)c2nc(C)nc3cc(C)[nH]c23)cc1 +O=C(Cc1ccc2ccccc2c1)Nc1cnc(-n2cccn2)nc1O +CC(NS(C)(=O)=O)c1ccc(CN2CCOC(c3ccc(F)cc3)C2)cc1 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncon2)c1 +O=c1oc2c(Br)c(O)c(Br)cc2cc1-c1nnn[nH]1 +N=C(N)Nc1ccc(N2C(=O)N(Cc3ccccc3)N=C(C3CCCCC3)c3ccccc32)cc1 +Cc1nc2c(cc1Nc1nc(Cl)cn(C(C)C3CC3)c1=O)COC2 +Cc1ccccc1C(CC(=NO)c1ccncc1)c1ccc(Br)cc1 +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(OC)cc1)C(=O)c1ccccc1C +CC(C)(C)c1nc2cc(S(=O)(=O)c3ccco3)ccc2n1CC1CCOCC1 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+O=C(NCc1nnc2n1CCCCC2)c1csc(-c2ccccc2)n1 +Cc1cccc(N2CCN(CCCCN3C(=O)CSC3(C)C)CC2)c1 +N#Cc1cccc2c(C3=CCN(CCC4OCCc5cc(C(N)=O)ccc54)CC3)c[nH]c12 +CCCC(C)CN1CCC(c2ccc(C(=O)N(C)C)cc2)(c2cccc(O)c2)CC1 +O=C(Cc1ccccc1)NC1CCN(Cc2ccc3cc(F)ccc3c2)C1 +COCCc1sc(S(=O)(=O)NC(=O)Nc2cc(C(F)(F)F)cc(C)n2)cc1C +COc1cc(CNc2ccc(Cc3c[nH]c4ncc(C)cc34)c(F)n2)c(F)cn1 +N#Cc1ccc(Cl)c(C(=O)c2c[nH]c3ncc(-c4cnn(C5CCNCC5)c4)cc23)c1 +NC(=O)c1cccc2c1C(=O)N(C1CCN(C3CCOCC3)CC1)C2 +Cc1nn(C)cc1-c1cnc(N)c(-c2ccc(C(=O)NC(CO)c3ccccc3)c(F)c2)c1 +O=C(O)C1CC1C(=O)c1ccc(N(Cc2ccc(Cl)cc2)CC2CC2)cn1 +CSc1nc(NC2CC(CO)C(O)C2O)c(-c2nc3ccccc3s2)c(=O)[nH]1 +CN1C(=N)NC(CCC2CCCCC2)(CC2CCCC(NC(=O)Nc3ccccc3)C2)C1=O +COc1cc(OC)cc(N(CCNC2CCN(S(N)(=O)=O)CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1nn(C)c(C)c1-c1cc(Nc2ccc(OC(F)(F)F)cc2)ncn1 +CC(=O)NC(C)c1ccc(OC2CN(c3cnc4ccccc4n3)C2)cc1 +CN(C)CCNC(=O)c1cccc2cc3cccc(F)c3nc12 +N#Cc1ccc(C(O)(c2cscn2)C(F)(F)F)cc1C(F)(F)F +Cc1cc(O)cc(C)c1CC(N)CN1Cc2ccccc2CC(NC(=O)Cc2ccccc2)C1=O +O=C(Nc1ccc(CC(NC(=O)C2CCC(=O)N2Cc2ccccc2)C(=O)O)cc1)c1ccccc1[N+](=O)[O-] +COc1ccc(OC)c(C=CC(=O)C(=Cc2ccc(O)c(F)c2)C(=O)C=Cc2cc(OC)ccc2OC)c1 +O=C(c1nn(-c2ccc(CN3CCC(O)C3)cc2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CN1CCN(C(=O)Nc2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +COc1cc(C(C)C)c(Oc2cnc(NCCNC(C)=O)nc2N)cc1I +CC(=O)N1CCC(C(=O)N2CCC(N(C)C(=O)c3ccc(C)cc3)C(c3ccc(Cl)c(Cl)c3)C2)CC1 +COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(Cc3ccncc3)c2c1 +COC1COCCC1NC1CC2CCCC2(C(=O)N2CCc3ncc(Br)cc3C2)C1 +CC(C)c1n[nH]c(Cl)c1-c1ccnc(Nc2ccc(N3CCC(N(C)C)CC3)cn2)n1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)C1CCC(=O)N1C +O=C(NC1CC1)c1ccc(-c2cnc3c(NCC4CCOCC4)cc(Oc4ccccc4F)nn23)cc1 +NC1CCC(Nc2cc(-c3cnc(Cl)c(NCC4CCOCC4)n3)c(Cl)cn2)CC1 +Cc1ccccc1C(=O)c1cnc(NCCCNS(=O)(=O)c2cccc(F)c2)s1 +O=C(Nc1ccc(C2=CCN(C(=O)c3cnccn3)CC2)cc1)N1Cc2ccncc2C1 +COCCNc1nc(-c2cnn(CCO)c2)cc2ncn(C)c(=O)c12 +O=C(O)c1ccc(-c2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)nc1 +O=c1ccn(CCCCCS(=O)(=O)NCc2cccc(OCC3CC3)c2)c(=O)[nH]1 +c1cncc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)c1 +Cc1ccccc1S(=O)(=O)NC(CNC(=O)c1ccccc1)C(=O)O +Cc1ccc(O)c(Oc2ccc(C#N)c(C(F)(F)F)c2)c1 +CC1CN(C(=O)OC2(C(F)(F)F)COC2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +COc1ccccc1N1CCN(CC(O)CN2C(=O)NC(=Cc3ccc(N(C)C)cc3)C2=O)CC1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2csc(Cc3ccccc3)n2)c1 +CCCCN(CC)c1cc(C)nc2c1NC(=O)CN2c1ccc(C(C)C)cc1Cl +Cc1cccc(NC(=O)Nc2c(-c3ccccc3)c3cc(C)c(C)cc3c(=O)n2C)c1 +Cc1cc2[nH]ncc2c2sc(NC(=O)C3(Nc4ccc(Cl)cc4)CC3)nc12 +NC(=O)c1cc(OC2CCNC2=O)nc(C2=CCC(Oc3ccc(C(F)(F)F)cc3)CC2)n1 +O=C(NO)C1(S(=O)(=O)c2ccc(OCCCn3nnc(-c4ccc(OC(F)(F)F)cc4)n3)cc2)CCOCC1 +N#CC1CC(NC2CC2)CCC1n1cc(C(N)=O)c(Nc2ccc(S(=O)(=O)C(F)(F)F)cc2)n1 +CNCCN1CCC(OCc2ccc(-c3ccccc3)cc2)CC1 +CCCCc1nc(NCc2ccccc2[N+](=O)[O-])c2sccc2n1 +CC(C)n1cc(C(=O)c2ccnc(NC(=O)Cc3coc(C4CC4)n3)c2)c2cnccc21 +CCN(CCOC)c1ccc(NC(=O)c2nc(-c3ccccc3)oc2C(F)(F)F)cn1 +CN(CC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)C(=O)c1ccc(Cl)s1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cnnn1-c1ccc2c(c1)OCCO2 +COc1ccc2cc3[n+](cc2c1OCCSc1ccccc1)CCc1cc2c(cc1-3)OCO2 +C=CC(C)(C)c1c(OC)cc(O)c2c(=O)c(OC)c(-c3ccccc3)oc12 +C=CC(C)(C)c1cc(CCCc2cc(O)c(O)c(CC3OC3(C)C)c2CC=C(C)C)c(O)cc1O +CC1(N)CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(Cl)c(O)c(Cl)c4)cc23)CC1 +O=C(Nc1ccccc1-c1nc2ccccc2[nH]c1=O)c1cccnc1 +CN(CCC1CN(C(=O)OCc2cc(Cl)cc(Cl)c2)CCO1)C(=O)c1c[nH]c(=O)o1 +Cc1ccc(C(=O)N2CCOCC2Cc2cc(-c3ncccn3)ccc2F)c(-n2nccn2)c1 +COc1ccc2c(c1)C(=O)C(=Cc1cc(Br)c(O)c(Br)c1)C2=O +CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(CCCI)C1CCC(CO)CC21 +Cc1cccc(C)c1Oc1cc(Nc2ccc(C#N)cc2)c([N+](=O)[O-])cc1[N+](=O)[O-] +COc1cccc(-c2cc(C(N)=O)c3[nH]c4cc(NC(=O)C5CCOCC5)ccc4c3c2)c1 +CCN(C(=O)c1ccc(CNc2ncnc(N3CCc4cc(F)ccc4C3)n2)cc1)c1cccc(C)c1 +COc1cc(CNC(=S)NC(CCc2ccc(C)c(C)c2)COC(=O)C(C)(C)C)c(I)cc1O +CC(C)(C)C(CO)NCC(=O)N1CCc2ccccc2C1C1CCCCC1 +CN(C(=O)C1C(c2ccccc2)=C1c1ccccc1)C1CCCCC1N1CCCC1 +O=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCC5(CC4)COC5)cc3)cc12 +O=S(=O)(c1cccc(F)c1)c1cccc2oc(N3CCNCC3)nc12 +COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccccc1[N+](=O)[O-] +CC1(C)C2CC3OB(C(CCCCN)NC(=O)C4CCCN4C(=O)c4ccccc4Cc4ccccc4)OC3(C)C1C2 +COc1ccc(OC)c(N2CCOc3cc(S(=O)(=O)Nc4nccs4)ccc32)c1 +CNC(C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl)c1ccccc1 +CC1(O)CCC(Nc2c(C(N)=O)cnn3cc(-c4ccccc4C(N)=O)cc23)CC1 +CC(C)=CCOc1cc(Oc2ccc(S(=O)(=O)N3CCC(F)C3)cc2)cc(C(=O)Nc2cc(C)n(C)n2)c1 +CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)C(CC(C)C)NC(=O)N2CCCCCC2)CC1 +COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)CCC(C)C)CC1)C(=O)C2 +N#Cc1nc(Nc2ccc([N+](=O)[O-])cc2)nc(NC2CCCCC2)n1 +O=C(CCO)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1cccnc1-n1cc2ccccc2n1 +COc1cc(N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1 +COc1cc(C(=O)Nc2cnc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)ccc1F +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCc2ccc(CNC(=O)c3ccc(Cl)cc3)cc2)C1 +CCOC(=O)c1c(-c2cccc(OC)c2)[nH]c2cc(OC)c(Cl)cc2c1=O +COc1ccc2[nH]c(C(=O)c3cccc(N)c3)cc2c1 +COc1cccc(C2(c3cccc(OC)c3)CC3c4ccccc4C2c2cccc[n+]23)c1 +Cc1c(Nc2c(C#N)cncc2C=CCCN2CCC(N(C)C)CC2)ccc2[nH]ccc12 +O=C1NC(=O)C(c2ccc(-c3ccc4ccccc4c3)[nH]c2=O)(C2CCCCC2)O1 +CCc1nc2c(-c3ccc(OC)nc3C(F)(F)F)ccnc2n1C(C)CC +O=C(COc1cccc2[nH]cc(S(=O)(=O)c3ccc4ccccc4c3)c12)NS(=O)(=O)c1cc(F)cc(F)c1 +CCOc1ccc(C(=O)Nc2ccc(C3CCCNC3)cc2)nc1 +COc1cccc(-c2ccc3c(c2)CCN(CC(=O)Nc2cc(Cl)cc(Cl)c2)C3C2CCN(C3CCCC3)CC2)c1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cc(-c2cccc(Cl)c2)[nH]n1 +CC(=NOCc1ccc(-c2ccccc2)cc1)c1ccc(CNCCC(=O)O)cc1 +Cn1ncc(NCc2ccncc2)c1C(=O)Nc1cccc(C(F)(F)F)c1 +CCCOCCn1c(=O)c(NCC(=O)N2CCCC2)nc2cnc(-c3ccc(OC)nc3)cc21 +COc1cc(-c2cn(C3CC(C(F)(F)F)CCN(Cc4ccccc4)C3=O)nn2)ccc1-n1cnc(C)c1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-c2csc(C)n2)c1 +CC(Nc1nc2c(cnn2C2CCCC2)c(=O)[nH]1)C(=O)Nc1ccc(F)cc1 +O=C1NC(CCCN2CC=C(c3ccccc3)CC2)=NC2CCOCC12 +N#Cc1cc(Cl)cc(Oc2cc(OCc3nc4cccc(Cl)c4[nH]3)ccc2Cl)c1 +Cc1ccc(CC(=O)Nc2cc(-c3ccccc3-c3nnn[nH]3)ccc2N2CC3CC2CN3Cc2ccccc2)cc1 +Cn1nccc1-c1cc(Cl)ccc1-c1cn(C)c2cc(S(=O)(=O)Nc3ncns3)ccc12 +CNC(=O)C(=O)C(CCCCN)NC(=O)CN(C)C(=O)c1ccccc1Sc1ccccc1C#N +COc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCC2)[nH]1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NCc4cccc(Cl)c4)nc23)N1 +COCC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1ccccc1 +Nc1cccc(Cn2c(-c3ccc(Oc4cncnc4)cc3)ccc2-c2ccccc2Cl)n1 +CNC(=O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12 +CC(c1ccccc1Cl)N1CCC(n2c(O)nc3ccccc32)CC1 +COc1cc2c(cc1OC)C(=O)C(C(=O)Nc1ccc(C)cc1)C2 +O=C(NCCc1ccc(Cl)c(F)c1)c1ccc2cnc(NC3CCOCC3)cc2n1 +CC1(C(=O)N(CCCC(=O)O)Cc2ccc3ccoc3c2)CCN1C(=O)c1csc2ccccc12 +CCNC(=O)c1cc2c(N3CCCC3c3cccnc3)ccnc2[nH]1 +Oc1ccc2c3c1OC1c4[nH]c5c(OCc6ccccc6)cccc5c4CC4(O)C(C2)N(CC2CC2)CCC314 +COc1ccc(Oc2c(Cl)cnn(-c3cccc4c3CCCC4)c2=O)cc1 +O=C1CCC(=O)N1c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F +O=C(O)CS(=O)(=O)N1CCC(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +Nc1nc(SCc2ccccc2)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1c(C(=O)NCCc2ccc(Cl)cc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +NC(Cc1ccc(O)cc1)C(=O)Nc1nc2ccc(C(=O)c3ccccc3)cc2[nH]1 +CNCCCN1Cc2ccccc2N(c2ccc(F)c(F)c2)S1(=O)=O +CCCC(c1ccccc1)N(CCC)c1nc(-c2ccc(Cl)cc2OC)n(C)n1 +O=C(O)c1cccc(COc2cccc(CCS)c2C(=O)O)c1 +Cc1cn(C2CC(O)C(CNC(=O)Nc3ccc(OCc4cccc(Cl)c4)cc3)O2)c(=O)[nH]c1=O +CC(OCC1(c2ccccc2)CC(NS(C)(=O)=O)C(=O)N1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(C)(C)CC(=O)N1CCC(N(c2ccc(Cl)cc2)c2cccnc2)CC1 +CC(O)Cn1c2cnccc2c2cnc(Nc3ccc(N4CCNC(C)C4)nn3)nc21 +O=C(Nc1ccc2c(c1)CCNC2)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CCCS(=O)(=O)N1CCCC(Nc2ncccc2-c2cnc3nc[nH]c3n2)C1 +CCOc1cc(=O)n(C)cc1-c1cc(CS(C)(=O)=O)ccc1Oc1ccc(F)cc1F +CCC12CCC(=O)C(Br)=C1c1ccc3[nH]ncc3c1C2 +CC(C)(C)OC(=O)n1c(-c2ccc(CCC#N)cc2)cc2ccccc21 +CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N(C)C)c1=O +O=C(NC1CCCCCCC1)c1ccc(CN2C(=O)Nc3ccc(Cl)cc3S2(=O)=O)cc1 +O=[N+]([O-])c1ccc(-c2csc3ncnc(N4CCC(COCCN5CCCC5)CC4)c23)cc1 +COc1cc2c(cc1OC)C1=NOC(CN3CCN(CC(C)=Cc4ccsc4)CC3)C1CO2 +COc1ccc(-c2cc(-c3ccc(F)cc3F)n3c(CN4CCOCC4)cnc3c2C#N)c(OC)c1OC +CC(CCc1ccc(Oc2ccccc2F)cc1)(C(=O)NO)S(C)(=O)=O +O=S(=O)(c1ccc2oc(N3CCNCC3)nc2c1)c1cccc2ccccc12 +COc1ccc(-c2cn(C(C)=O)c(=O)n2-c2cc(OC)c(OC)c(OC)c2)cc1 +CCn1c(=Cc2ccc3ccccc3[n+]2CC)sc(=C2Sc3ccccc3N2C)c1=O +CC(C)Cc1cn(-c2nc(C(=O)O)cs2)c2cc(C(F)(F)F)ccc12 +Cc1cc(C)cc(S(=O)(=O)n2c(SCC(=O)Nc3ccc(C)cc3Cl)nc3ccccc32)c1 +COC1CN(c2nc(-c3cccc(C)c3OCc3cc(C)c4c(c3)CCN(CC3COCCO3)C4)cs2)CCC1C(=O)O +O=C(O)CC(NC(=O)OCc1ccccc1)C(=O)COC(=O)Cc1c(Cl)ccc(Cl)c1Cl +Cc1nc2ccc(N=c3[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n3Cc3ccc(Cl)cc3)cc2o1 +CC(O)(C(=O)Nc1ccc(S(=O)(=O)NCCN2CCCC2)cc1Cl)C(F)(F)F +CCS(=O)(=O)N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +CCN1C(=Cc2sc3ccc(Cl)cc3[n+]2CC)C=Cc2cc(OC)ccc21 +CCN1CCN(c2nc3ccccc3c3c2COc2ccccc2-3)CC1 +CC1=C(c2ncnn2-c2ccccc2F)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])C(=O)Nc1cccc2ccccc12 +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2cc3ccccn3n2)c1 +CCc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)NS(=O)(=O)C1CC1)n2Cc1cc(F)ccc1F +NS(=O)(=O)c1ccc(CNc2ncnc(NCc3ccccc3)c2[N+](=O)[O-])cc1 +CNC1CCN(C(=O)c2ccc(-c3[nH]nc4c3C(=O)c3c(NC(=O)NN5CCOCC5)cccc3-4)s2)C1 +CCCCNC(=O)C(C)CC(O)C1CSCCCCCSCC(NC(C)=O)C(=O)NC(C)C(=O)N1 +CN(C)C1CN(c2cc(-c3cnc(N)c(OC(F)F)c3)nc(N3CCC(F)(F)C3)n2)C1 +CCCCCCCCCCCCC(=O)N1CCC2C(C)C(O)CCC2(C)C1 +OCC(NC1CCN(CCCc2c[nH]c3ccc(Cn4cncn4)cc23)CC1)c1ccccc1 +COc1ccc(C2(C(=S)NCCCn3cncc3C)CC2)cc1OC +O=c1[nH]nc(Cc2ccc(-c3ccc(Cc4n[nH]c(=O)c5c4CCCC5)cn3)nc2)c2c1CCCC2 +CN(C)CCc1c[nH]c2ccc(CCN3CCN(C)S3(=O)=O)cc12 +COc1cc2ncnc(N3CCN(C(S)=Nc4cccc([N+](=O)[O-])c4)CC3)c2cc1OC +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1NC(=O)c1cnc(NC(C)C)nc1 +O=C(O)CN1C(=O)C(=Cc2ccc(-c3cc(C(F)(F)F)ccc3Cl)o2)SC1=S +COCCn1cnc(CCNc2cc[nH]c(=O)c2-c2nc3c(C)cc(N4CCOCC4)cc3[nH]2)c1 +CN(C(=O)c1ccc(N(C)C2CCN(c3ncnc4[nH]ccc34)C2)nc1)c1ccc(F)cc1 +CC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ccc(OCC5CC5(F)F)cn4)C3)cc2)s1 +CCCCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3cccc(OC)c3)CC2)cc1 +COc1ccc(N(C)c2cc(OC)c(OC)c(OC)c2)cc1 +O=C(C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1)N1CC(c2ccccc2)(c2ccccc2)C1 +COc1ccc(C=Cc2ccc3ccc(C(=O)O)c(O)c3n2)cc1O +Cc1cc(N(C)CCN(C)C)nc2ccc(NC(=O)c3ccc(-c4ccccc4)cc3)cc12 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+CCCCCN(C)C(=O)C(=O)c1c(-c2ccc(Cl)cc2)[nH]c2ccc(Cl)cc12 +O=C(CCCCC1CCSS1)NCC(O)CNc1c2c(nc3cc(Cl)ccc13)CCCC2 +COc1nc(Nc2ccc(C#N)c(OCC=C(C)C)c2)nc(OCCN2CCN(C)CC2)n1 +COc1ccc(Nc2snc(SCc3ccc(Cl)cc3)c2C(N)=O)cn1 +O=C(Nc1cccc(-c2ncnc3cc(-c4ccncc4)sc23)c1)c1cccc(C(F)(F)F)c1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1NC1CCOC1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nnc(Nc2cccc(Oc3ccccc3)c2)o1 +Cc1c(C(C)c2c(F)cccc2F)nc(Nc2ccc(C#N)cc2)[nH]c1=O +O=C(NCc1ccc(-c2ccccc2)cn1)C(O)C(O)C(=O)N1CCCC1c1cccc(Cl)c1 +CN(C)CCC=Cc1ccc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2c1 +CC(C)c1ccc(C(O)(c2ccc(C(F)(F)F)cc2)c2cccnc2)cc1 +O=c1[nH]c(C2CNCC2c2ccc(C(F)(F)F)cc2)nc2ccc(-c3cn[nH]c3)cc12 +COc1ccc(C(C)=NNC(=O)C2CC2c2ccccc2)cc1OC +O=C(NC(Cc1ccccc1)C(=O)NC(CCS)C(=O)O)c1cc2ccccc2[nH]1 +NC(=O)c1cc(-c2ccn[nH]2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc12 +CCCOc1ccc(NC(=O)c2ccc(F)cc2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 +COc1ccccc1N1CCN(CCn2nc(N3CCN(C(=O)c4ccco4)CC3)ccc2=O)CC1 +Cc1sc(N)nc1-c1ccc2[nH]c3c4c(c5c(c3c2c1)C(=O)NC5=O)CCC4 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+CNc1nc2[nH]c(-c3cccc(CNC(=O)C4(C)CC4)n3)cc2c2c1ncn2C +Cc1ccc(N2CCOCC2)cc1N1CCN(C(=O)c2cccc(Cl)c2Cl)CC1=O +Cc1cccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)c1 +C=CCC1C(=O)N(CCN(C)C)c2cccc(C(F)(F)F)c2CC1c1ccc(OC)cc1 +N#CCC1(n2cc(C(N)=O)c(Nc3cccnc3)n2)CCN(C(=O)OCC(F)(F)F)CC1 +CCc1ccc(C(=O)NCC2c3[nH]c4ccccc4c3CC3C4c5[nH]c6ccccc6c5CC(C(C#N)N23)N4C)cc1 +N=C(N)c1ccc2cc(C(=O)Nc3ccccc3)cc(Br)c2c1 +O=C(NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1)C1CC(Cl)C1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2c(Br)cccc21 +CCCCN1CC2(CN1Cc1ccc(-c3ccccc3S(=O)(=O)NC(=O)c3ccccc3)cc1)C(=O)CCC2=O +COC(=O)c1c(C(=O)OC)c(C(C)C)n(CCC2CC(O)CC(=O)O2)c1-c1ccc(F)cc1 +N#Cc1ccc2ccc(=O)n(CCN3CCC(NCc4ccc5c(n4)NC(=O)CO5)CC3)c2c1 +CS(=O)(=O)NCCn1ccc2cc(C(=O)N3CCC(N4C(=O)OCc5ccccc54)CC3)ccc21 +CN(Cc1ccc2nc(N)nc(N)c2n1)c1ccc(Cl)c(Cl)c1 +CC(=O)Nc1cccc(OP(=O)(Oc2cccc(NC(C)=O)c2)C2CCCN2C(=O)C2CCCN2)c1 +COc1ccccc1CN(CCCCCCCCN(Cc1ccccc1OC)C(=O)CCCCCN)C(=O)CCCCCN +O=C(NCCc1ccc(-c2ccccc2)cc1)C(CC#Cc1ccccc1F)NCP(=O)(O)O +CN(c1cc(F)c(C#N)c(F)c1)C1CCN(c2ncnc3[nH]ccc23)C1 +CN(C)CCNc1nc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2o1 +CNC(=O)C(C)(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)c1noc(C)n1 +COC(=O)C1(C)CCCC2(C)c3cc(Br)c4nc(N=Cc5cc(Cl)cc(Cl)c5O)[nH]c4c3CCC12 +N#CSc1c(-c2cccc(C(F)(F)F)c2)[nH]c2ccccc12 +O=C1C=C(c2ccccc2)C2(CCN(c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)CC2)O1 +Cn1cc(-c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)cn1 +O=C(O)CCCCCC(CNS(=O)(=O)c1ccccc1)c1cccnc1 +FC(F)(F)c1ccc(Nc2nc(N3CCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CC1CN(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4Cl)nc23)CCN1C(=O)OC(C)(C)C +CC(OC1CCC(N(C)CC2CCC(=O)N2)C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=c1ccc2c(OCCCCCOc3ccccc3)c3ccoc3cc2o1 +CC(C)CCNC(=O)c1ccc(N2CCC(Oc3cccc(F)c3F)CC2)nn1 +COc1ccc(-c2nnc(C(=O)N3CC(Oc4ccc(CN(C)C)c(C)c4)C3)o2)cc1 +O=c1ccc2ccccc2n1CCCCCN1CCN(c2cccc3sccc23)CC1 +Cn1ccc(COc2cc(F)c3nc(C4CCCCC4C(=O)O)n(Cc4ccc(N5CC(F)(F)C5)cc4)c3c2)n1 +CC(c1ccccc1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 +COc1cc(CC2C(C)(C)CC(C)=CC23CC3)c(OC(C)=O)cc1Br +CC1CN(c2nnc(N3CCC(N4CCCCC4)CC3)s2)CC(C)O1 +COc1ccc(F)cc1-c1c[nH]c2c(NC(C)=O)cccc12 +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCc3ccc(CC(C)C)cc3)ccc21 +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3C#N)cc2)cc1 +Cc1ccc(-n2nc(NC(=O)C3CNC(=O)C3C)cc2-c2cccc(OC(F)(F)F)c2)cc1 +Cc1cc(NC(CCCCNCc2ccc(Cl)cc2)C(=O)NO)cc(C)c1F +O=C(Nc1ccc2cc(CN3CCCC3)cnc2c1)c1ccc(-c2ccc(F)cc2)nc1 +Nc1nc2c(s1)CN=C(c1ccccc1F)c1cc(Cl)ccc1-2 +COc1cccc(C(=O)Nc2ccc(OC)cc2C(=O)Nc2ccc(N3CCCCC3=O)cc2)c1 +N#CCCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +NC(=O)N1CCCc2cc(-c3cncc(-c4ccc(S(=O)(=O)NCCO)cc4)c3)cnc21 +OC(CNc1ccc(F)c(F)c1)(c1ccc(Cl)cc1)c1nnn(Cc2ccccc2)c1-c1ccc(Cl)cc1 +O=C(CC1CCCC1)Nc1ccc(NC(=O)N2Cc3ccc(-c4ccncc4)cc3C2)cc1 +Clc1ccc2c(NCCCCCCCCNc3c4c(nc5cc(Cl)ccc35)CCCC4)c3c(nc2c1)CCCC3 +COc1ccc(OCC(=O)Nc2ccc3nc(N4CCN(C)CC4)cc(C)c3c2)cc1 +COc1ccc(-c2cc3c(N)ncnc3nc2-c2cccs2)cc1Br +O=S(=O)(NC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC1 +CC#CCOc1ccc(S(=O)(=O)N2CCCSCC2C(=O)NO)cc1 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+CN(C)S(=O)(=O)c1c(Cl)ccc(NC(=NC#N)Nc2ccccc2F)c1O +COc1cc(-c2cn(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)cn2)cc(OC)c1O +CCCOc1cc(OCCCCN)cc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 +CSc1ccc(NC(=O)c2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1 +N#Cc1ccccc1OCC(O)CNCCNC(=O)Nc1ccc(OCCF)nc1 +COc1ccc2c(c1)C(=O)C(c1ccc(C(C)(C)C)cc1)=[N+]2[O-] +CNC(=O)C(=O)CCCCCCC(=O)Nc1ccc(-c2ccccc2)cc1 +COc1ccc(Cl)cc1N1CCN(C(=O)c2cc(-c3ccc(Cl)cc3)n[nH]2)CC1 +NC1=Nc2ccc([N+](=O)[O-])cc2C2CCCC12 +COC(=O)C(NC(=O)CCC(=O)C=Cc1ccc2c(c1)OCO2)C(C)C +COc1ccccc1N(CC(=O)N1CCCCC1)S(=O)(=O)c1ccccc1 +O=C(CCCCCCCC(=O)c1ccc(-c2ccccc2)cc1)NO +Cc1cc(NC(=O)OC(C)(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1 +COc1ccc(NC(=O)Nc2ccc3c(c2)c2c4c(c5c(c2n3CC(C)C)CCc2nn(C)cc2-5)C(=O)NC4)cc1 +N#Cc1cc(S(=O)(=O)Nc2cscn2)ccc1Oc1ccc(Cl)cc1-c1cn[nH]c1 +COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(OCCN3CCCCC3)cc2)cc1 +CN(C(=O)c1ccc(OCC2CC2)cn1)C1Cc2ccc(CN3CCCCC3)cc2C1 +O=C(C=Cc1ccccc1)c1ccc(Nc2nc(-c3ccccc3)nc3ccccc23)cc1 +O=C(O)C1=C(C=Cc2cccc[n+]2[O-])CS(=O)(=O)C2C(=Cc3ccccn3)C(=O)N12 +O=C(NC1CC1c1ccccc1)N1CCC(c2ncon2)CC1 +CSCCC(NC(=O)c1cccc(CN(Cc2ccc(C#N)cc2)Cc2cncn2Cc2ccc(C#N)cc2)c1)C(=O)O +O=C(COc1ccccc1)Nc1nc2nn(CCCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +CCCCC1CCN(C(C)C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(OCCC)CN2)C1=O +NC1(c2ccc(-c3nc4ccc(O)cn4c3-c3ccccc3)cc2)CCC1 +CCc1nn2ccc(Cl)cc2c1C(=O)NCc1ccc(N2CCC(c3ccc(OC(F)(F)F)cc3)CC2)cc1 +CSc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNC4)C3=O)ccc12 +Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 +CCCCCC(C)NC(=O)C1CCN(Cc2ccc(Cl)cc2Cl)CC1 +CCn1c2ccccc2c2cc(NC(=O)CCN3CCOCC3)ccc21 +Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CN)cc3)ccc2n1 +NC1=NC(c2cc(NC(=O)c3ncc(Br)cc3C(F)F)ccc2F)(C(F)F)C2CC2O1 +Cc1ccc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)F)o1 +COc1ccc(N(C)Cc2ccc3nc(N)nc(N)c3n2)c(OC)c1 +CCN(CC)c1cccc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(C)c34)cc2)c1 +CCCC(C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)c(Cl)c1 +Cc1cccc(Nc2ncnc3c2sc2ccc(N)cc23)c1 +Nc1ncnc2cc(CN3CCN(S(=O)(=O)c4cc5ccc(Cl)cc5s4)CC3=O)ccc12 +O=C(NCc1ccccc1)c1cnc(Nc2cccc(F)c2)nc1C(F)(F)F +CC1CCC(NC(=O)c2cc3cc(Br)cnc3n(CCN3CCOCC3)c2=O)CC1 +CCCCC(=O)NC(c1ccco1)c1cc(Cl)c2cccnc2c1O +Fc1ccc(CN2CCN(c3ccc(-c4nc5ccccc5o4)cc3)CC2)cn1 +Cc1cncn1CCCNC(=C[N+](=O)[O-])Nc1ccc2c(c1)OCO2 +NCCCCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(CCc3ccccc32)CC1 +O=C(CCC1CCCC1)NC1CCC(Nc2ccnc3cc(Cl)ccc23)CC1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)OCc2ccccc2)c1 +COc1ccc(-c2c(N)ncnc2N2CCC(c3nc(-c4ccc(F)c(C(F)(F)F)c4)cn3C)CC2)cc1 +Clc1ccc(OCCN2C3CCC2c2c([nH]c4ccccc24)C3)cc1 +COc1ccccc1CCNCc1ccc(CCNCCc2ccc(O)c3[nH]c(=O)sc23)cc1 +O=C(NCC(CNC(=O)c1ccc[nH]1)OC1OC(CO)C(O)C(O)C1O)c1ccc[nH]1 +N=C(N)NCCCC1NC(=O)CNC(=O)CCSCC(C(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC1=O +N#CC(=Cc1ccc([N+](=O)[O-])o1)c1nc2ccccc2[nH]1 +CN1CCN(c2cc3c4c(cccc4n2)-c2ccccc2-3)CC1 +Cc1csc(C(C)(O)c2nnc(Nc3cc(C4CC4)n(Cc4c(F)cccc4F)n3)s2)n1 +Cn1c(N2CCOC(c3ccc(F)cc3)C2)nc(-c2ccncc2Cl)cc1=O +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(C(F)(F)F)c(F)c3)cn2CCN2CCCC2)CC1 +CCC(C(=O)OC(C)(C)C)N1C(=O)C(C)(Cc2nnn[nH]2)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC(O)CC2 +Cc1cc(C)cc(Cc2c(C)c(C)[nH]c(=O)c2N(C)C)c1 +CCCOc1ccc(-c2nn3c(NC4CCCC4)nccc3c2-c2ccnc(NC3CCCC3)n2)cc1 +COc1cc(Sc2c(-c3ncco3)[nH]c3ccccc23)cc(OC)c1OC +COc1cc(NC(=C[N+](=O)[O-])NCCCn2cncc2C)cc(OC)c1OC +CCc1nc2n(c1C(=O)N(CCC(F)(F)F)CC1CC1)CCN2c1c(C)cc(C)cc1C +O=C(CSc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl)C(F)(F)F +COc1ccccc1N1CCN(CCC(=NO)c2ccsc2)CC1 +Cc1nn(Cc2ccc(-c3cc4ccc(Cl)cc4[nH]3)cc2)c(C)c1CC(=O)O +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)SCCc1ccccc1 +O=C1c2ccccc2C(=O)N1CCCCNCCc1ccccc1 +O=C(O)CCCCc1cc2cc(C(=O)NC3CCCc4ccccc43)ccc2c(=O)n1-c1ccc(F)cc1 +O=C1COc2ccc(N3CCc4ccc(F)cc4CC3)cc2N1 +CC1(C)CCC(Oc2cc(F)c(C(=O)NS(C)(=O)=O)cc2Cl)CC1 +COc1ccc(-c2nc3c(c(Nc4ccc(CC(=O)O)cc4)n2)S(=O)(=O)CCC3)cc1F +O=C(NC1Cc2ccccc2C1O)c1cn(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)n1 +CCC(C)(CC)OC(=O)CC(C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +CC1(F)CC(F)(F)C(C)(c2cc(NC(=O)c3ccc(OC(F)F)cn3)ccc2F)N=C1N +Nc1nc(Nc2ccc(N3CCN(C4CC5CCC4C5)CC3)cc2)nn1-c1ncnc2ccc(Cl)cc12 +COc1cc2oc(-c3cn4nc(SC)sc4n3)cc2cc1Br +COC(=O)CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(C)=O)c2)n1C +CCCOC1C=C(C(=O)O)CC(N=C(N)N)C1NC(C)=O +O=C(Nc1ccccc1)OC1CC2CCCCC2C1C=Cc1ccc(-c2cccc(F)c2)cn1 +Brc1cnc(NCc2cnn(-c3ccccc3)n2)nc1Nc1cc(C2CC2)n[nH]1 +O=C1CC(O)CC(C=Cc2c(Cl)cc(Cl)cc2OCc2cccc(F)c2)O1 +CC(C)(C)OC(=O)NC(C(=O)N1CC2C(C1C(=O)NC(CC1CC1)C(=O)C(N)=O)C2(C)C)C1(C)CC1 +CCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCC)NC(=O)c1ccccc1 +C#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(C)c1 +CCCCc1nc(-c2ccccc2Cl)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN(C)CCCn1nc2c3c1ccc1c(=O)n(CCN(C)C)c(=O)n(c13)-c1ccccc1-2 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)oc3C)ccc21 +COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)COc3ccccc3[N+](=O)[O-])cc1)CC2 +Cc1cccc(-c2c[nH]c3ncc(-c4cccc(NC(=O)C=CCN(C)C)c4)cc23)c1F 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+O=C1N(Cc2cccc3c2OCCN3)CCCC12CCN(c1cnc3ccccc3n1)CC2 +CC(C)N(CCO)Cc1csc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)n1 +CC(C)(C)c1ccc(CN(Cc2ccccc2)C2=NCC(CBr)S2)cc1 +Cc1cn2cc(C(=O)N3CCOCC3)cc2c(C#Cc2cccc(C(F)(F)F)c2)n1 +CCc1ccc2ncc(C(=O)OCC(CC)CC)c(O)c2c1 +COc1ccc(-n2cnc3c(NC(C4CC4)C4CC4)nc(C)nc32)c(C)c1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCc2ccccc2)C1c1[nH]c(CC)nc1Cl +CC1=C(c2ccc(OCCCN3CCCC3C)cc2)SC2=NCc3ccccc3CN21 +CN(CC=Cc1ccccc1C(F)(F)F)Cc1ccc2c(c1)OCCC2 +Cc1c(Cc2c(F)cccc2F)nc(Nc2ccc(C#N)cc2)[nH]c1=O +Cc1cc2c(cc1Cl)N(C(=O)Nc1ccc(OC(CCN(C)C)c3ccccc3)cc1)CC2 +COC(=O)C1C(OC(=O)c2ccc(I)cc2O)CC2CCC1N2C +COC(=O)CCc1ccc(-c2ccc3c(=O)n(CC4CCC(c5ccccc5)O4)c(N)nc3c2)cc1 +COC1CCC(c2cnc(N)c(-c3ccc(C(=O)NC(CO)c4cc(F)cc(Br)c4)c(F)c3)n2)CC1O +CC(=NO)c1ccc(OCCCc2c[nH]cn2)c(C)c1 +Cc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 +COc1ccccc1C1CCCN(c2cc(-c3ccncn3)cc(=O)n2C)C1 +COC(=O)CCCCC(=O)Nc1ccc2c3cccc4c3c(c3ccccc3n4C)[n+](C)c2c1 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(C)s2)CC1 +Cc1cccc(S(=O)(=O)c2c(C(=O)NCCO)[nH]c3ccc(Cl)cc23)c1 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+CC(C)(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1c(N)cc(Cl)cc1Cl +Cc1ccc(Cn2cnc(=O)c3cc(Oc4ncccc4C(F)(F)F)ccc32)cc1 +CCC1CC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2nc(C)ccc2N1C(=O)OC(C)C +Fc1cccc(F)c1-c1nc(-c2ccccc2)c(-c2ccc3nc[nH]c3c2)[nH]1 +O=C1COc2cc(Nc3cccc(C(F)(F)F)c3)ccc2N1 +CC(c1ccc(O)c(I)c1)C(O)C=CC1C2CCC(O2)C1CC=CCCCC(=O)O +CN1C2CCC1C1COC(=O)CCCCCC(=O)Nc3ccc(cc3)C1C2 +CCN1CCN(C(c2ccc(C(F)(F)F)cc2)c2cc(Cl)c3cccnc3c2O)CC1 +CC1(C)Oc2cc(-c3cccc(C(F)(F)F)c3)ccc2-c2[nH]c(-c3c(F)cccc3Cl)nc21 +COc1cccc(OC)c1OCCNCC1COC(c2ccccc2)(c2ccccc2)O1 +O=c1cc(-c2cc(F)ccc2F)oc2c1ccc1ccccc12 +COc1ccc(-c2[nH]c(-c3cccs3)nc2CCNS(=O)(=O)N2CCN(c3ccccc3Cl)CC2)cc1 +CCCCc1ncc(C=C(Cc2ccc(OC)s2)C(=O)O)n1Cc1ccccc1Cl +CCC(CC)(c1cc2ccccc2o1)c1c[nH]c2c(NS(C)(=O)=O)cccc12 +O=C(c1cccc(-n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)c1)N1CCCC(CO)C1 +CC(C)CC(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)N2CCCC2=O)CC1 +Cc1cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)ccc1F +CC1CCN(c2cc(-c3ccnc(NC(C)c4ccccc4)n3)c(-c3cccc(C(F)(F)F)c3)nn2)CC1 +N#CC1(NC(=O)C2CC(S(=O)(=O)c3ccccc3)CC2C(=O)N2CC3CCC(C2)O3)CC1 +CNCc1cc(N)c(Nc2ccc(C#N)cc2)cc1Oc1c(C)cc(C#N)cc1C +O=C1CCN(Cc2ccc(C(F)(F)F)cc2)CC1C(c1ccc(F)cc1)c1ccc(F)cc1 +CC(C)Oc1cccc(-c2ccc(CCNC(=O)c3ccc4c(c3)C3(C)CCN(CC5CC5)C(C4)C3C)cc2)c1 +CC(N)C(=O)N1CCC(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)F)cc2)cs1 +Cn1cc(Nc2ncc(Cl)c(NC3C4CCC(C4)C3C(N)=O)n2)cn1 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3ccccc3Cl)o2)c1 +CSc1ccc(C2CCC(OCC3CCN(C(=O)OC(C)(C)C)CC3)CC2)cc1 +N#Cc1c[nH]c2ccc(C3(Cc4ccccc4)CCNC3)cc12 +CC(C)(C)OC(=O)N1CCN(CCCCOc2ccccc2NC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 +COCC[N+]1(C)C2CCC1CC(CC(C#N)(c1ccccc1)c1ccccc1)C2 +C=C(c1ccc(C(C)(O)C(F)(F)F)cc1)N(C1CCC(c2ccccn2)CC1)C1CC1 +CC1CC(c2ccncc2NC(=O)c2nc(-c3c(F)cccc3F)sc2N)CC(N)C1OCCC#N +CCn1c(=N)n(CC(=O)c2ccc(Cl)cc2)c2ccccc21 +COn1c(NC(c2ccc(Cl)cc2)C(C)C)nc2c(c1=O)CN(C(=O)c1ccc(-n3ccnc3)cc1)CC2 +O=C(NCCS(=O)(=O)O)C1CCCN(C(=O)CCC2CCNCC2)C1 +COc1ccc(CCc2cnc3c(N)nc4cc(C=CP(=O)(O)O)ccc4c3c2)c(C)c1 +COc1ccc(N2Cc3cnc(Nc4ccc(F)cc4)nc3N(C3CCC(O)C3)C2=O)cc1 +O=C(CCCN1CCN(c2cccc(Cl)c2)CC1)NCc1nc2ccc(F)cc2c(=O)n1-c1ccccc1 +Nc1cccc(Nc2nc(NCCO)nc(NCCc3ccc(Nc4nc(NCCO)nc(Nc5ccc(F)cc5)n4)cc3)n2)c1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3Br)ccc2[nH]1 +CC(c1ccc(C(=O)NCCC(=O)O)cc1)N1C(=O)C(c2cccc(Cl)c2)=NC12CCC(C(C)(C)C)CC2 +CC(N)(COP(=O)(O)O)c1nc(-c2ccc(OCCc3ccc(-c4ccccc4)cc3)cc2)c[nH]1 +O=C(NCC(NS(=O)(=O)c1ccccc1)P(=O)(O)O)c1ccc(OCCC2CCNCC2)cc1 +FC(F)(F)c1ccc(Nc2ccnc3nc(-c4ncccc4C(F)(F)F)ccc23)nc1 +CN(C)Cc1ccc(-n2cc3cccc(C(N)=O)c3n2)cc1 +CC(C(=O)NC(C#N)CC(N)=O)N(Cc1ccc(-c2cccc(F)c2)cc1)S(C)(=O)=O +Fc1ccc(Br)c(F)c1C1CC(c2cccc(Br)c2)Nc2nnnn21 +O=C(Nc1cc(-c2cc3c([nH]2)C2(CCCNC2)CNC3=O)ccn1)c1ccc(C(F)(F)F)cc1 +Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)c(F)c3)(C(F)(F)F)C2)cc1 +COc1ccc(-c2csc(=O)[nH]2)cc1S(=O)(=O)NC1CCCC1 +CCN(CC)CCCC(C)Nc1c2c(nc3ccccc13)CCCC2 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C(C)CNCc1cccn1C +CCCC#CC1(C(F)(F)F)OC(=O)Nc2cccc(F)c21 +COc1cc(C2Nc3ccc(C(=N)N)cc3C3c4ccccc4CC23)ccc1O +COCCOCCOCCOCCOCCOCCOCCOCCOCCOC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CCC2)C1O5 +Oc1cccc(C(Nc2nccs2)c2ccc3cccnc3c2O)c1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2c(C)noc21 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cncc3ccccc23)cc1 +CCCCN(C)c1nc(NCc2ccccc2)c(C(=O)O)c(SCc2ccccc2)n1 +CC(C)CC(C(=O)O)c1cc(C=Cc2ccc(-c3ccccc3)cc2)cc(-c2ccc(Cl)c(C(F)(F)F)c2)c1 +CCCCCNC(=O)NCCCCC=CCCCCCCC(=O)NS(C)(=O)=O +COc1n[nH]c2cc(NC(=O)NC(C)c3cccc(Cl)c3)nc(CO)c12 +CNc1cc2nc(C)c(-c3cc(NC(=O)NCCC(C)(C)F)c(F)cc3C)cc2cn1 +COc1ccccc1C(=O)Nc1ccc2c(c1)CCCN2C(=O)c1ccccc1 +Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Br)cc5OC(F)(F)F)CC4)cc3)c12 +COC(=O)C=C1C(=O)N2C(C(=O)O)=C(COC(C)=O)CS(=O)(=O)C12 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(CC(N)=O)cc3)NC(=O)NC1=O)C2 +COc1ccc(C(=O)Nc2cccnc2)cc1OC1CCCC1 +CNC(=O)c1cccc(Nc2ncnc(N3CC(Oc4cc(Cl)ccc4Cl)C3)n2)c1 +C#CCN(C)C(=O)C=C1c2nc3ccccc3cc2C(=O)N1c1ccc(Cl)cc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(-c4cccc(N5CCSCC5)n4)cc3)NC(=O)NC1=O)C2 +CCC1(C)CN(C(=O)CN2CC(C)NCC2COC)c2cc(Cl)ccc21 +Cc1n[nH]cc1-c1cc2nc(CN3CCC(c4ccccc4)C3)[nH]c(=O)c2s1 +CCOC(=O)c1c(-c2cccc(OC(F)(F)F)c2)[nH]c2cc(OC)ccc2c1=O +Nc1nc(N=NNC(=O)Nc2cccc(Cl)c2)nc2c1ncn2C1OC(CO)C(O)C1O +CC(C)Oc1cc(Oc2cnc(C(=O)N(C)C)c(F)c2)cc(-c2nccc(=O)[nH]2)c1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cccc(N5CCN(CC(N)=O)CC5)c4)nc23)cc1 +COc1cc(-c2cc(F)cc(Cl)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +COc1ccc(-c2nc(-c3cccnc3)oc2Sc2ncccn2)c(OC)c1OC +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(-n4ccnc4)c3)s2)nn1 +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1Cl +Cc1cc(C2CN(Cc3c(C)cccc3F)CC2N(C)C)ccc1C(=O)Nc1ccncc1 +N#Cc1cnc(NC(=O)Nc2ccc(CCNCCc3ccc(F)cc3F)c(Cl)c2)cn1 +CCOC(=O)N1CCC(CNc2nc3c(s2)CCCc2ccc(F)cc2-3)CC1 +COc1ccc2c(c1)c1c(n2S(=O)(=O)c2cccc3ccccc23)CCCC1CN(C)C +COc1ccc(CN(CCCOc2cccc(CC(=O)O)c2)CC(c2ccccc2)c2ccccc2)cc1 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+CCN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)c1ccc(CN2CCC(C(N)=O)CC2)cc1 +O=C(c1nn(-c2cccc(OCCn3cccn3)c2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +COc1ccccc1Oc1ccc(S(C)(=O)=O)cc1-c1cn(C)c(=O)c2[nH]ccc12 +CC1CN(c2nc(N3CCOCC3)c3sc(-c4ccccn4)cc3n2)CC(C)O1 +CCc1ccc(S(=O)(=O)N=C2C=C(Nc3ccc(O)cc3)C(=O)c3ccccc32)cc1 +O=C(C=Cc1ccc(Sc2ccccc2OCc2c[nH]cn2)c(C(F)(F)F)c1C(F)(F)F)N1CCOCC1 +Cc1nc(NC(C)c2cccc(-c3cnc(N4CCN(C)CC4)nc3)c2)cc(-c2ccc3ncsc3c2)n1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(=O)O)c2ccccc2)c(C)c1 +O=C(C1CC(N2CCc3cc([N+](=O)[O-])ccc32)CN1)N1CCSC1 +CCN(CC)C(=O)Cc1c(-c2ccc(OC)cc2)nn2c(C)cc(C)nc12 +Cn1cnc(-c2ccnc(Nc3cc(Cl)c4[nH]c(C(=O)NC5CCCNC5)cc4c3)n2)c1 +O=C1N(Cc2cccc(-c3cccnc3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +COc1ccc(NCCNC(=O)C2(Oc3ccc(C4CCCCC4)cc3)CCCCC2)cc1 +NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CCc1ccc(-c2ncccn2)cc1 +CN1CCN(CCCOc2ccccc2Nc2nc(C#N)nc3c2ncn3C2CCCC2)CC1 +O=C1C(NS(=O)(=O)C=Cc2ccc(Cl)s2)CCN1c1ccc(-n2ccnc2CN2CCC(F)C2)cc1F +O=C1OC2(CN3CCC2CC3)CN1c1ccc2c(c1)OCO2 +CC(Cc1nc2cc(C=CC(=O)NO)ccc2n1CC(C)(C)CN(C)C)CC(C)(C)C +COCc1ncc(Cc2ccc3cccc(N)c3n2)c2cc(OC)c(OC)cc12 +COc1cc(C=CC(=O)OCCc2ccc(O)cc2)ccc1O +CC12CC(=O)C3C(CCC4CC(O)CCC43C)C1CC=C2C#N +CC1CN(Cc2ccccc2)CCN1c1nc(-c2ccncn2)cc(=O)n1C +Cc1cccc(Oc2ccc(C#N)c(C(F)(F)F)c2)c1 +Cc1cc(NC(=O)CC2CCCC2)ccc1N1CCC(N2CCCC2C)C1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2ccccc12 +Cc1[nH]cnc1CSCCN=C(NC#N)NCCCc1c[nH]cn1 +CC(C)n1cc(C(=O)c2cncc(NC3CCN(C=O)C3c3ccc(F)cc3)n2)c2c(N)ncnc21 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccoc3)n(CC(=O)N3CCC(C(=O)O)CC3)c2c1 +CC1c2cccc(C(N)=O)c2C(=O)N1C1CCN(CC2CCCCC2)CC1 +COc1cc(CC2COC(=O)C2Cc2ccc(O)c(OC)c2)ccc1O +CNC(=O)c1cc(Oc2ccc3[nH]c(Nc4ccccc4Br)nc3c2)ccn1 +CS(=O)(=O)Nc1cnc2ccc(-c3cnc4ccccc4c3)cc2c1Nc1ccc(N2CCNCC2)c(C(F)(F)F)c1 +C#Cc1cc(Cl)cc(N2C(=O)c3ccccc3C2(O)c2ccc3[nH]c(NC(=O)OC)nc3c2)c1C +C[n+]1c2n(c3ccccc31)N=C(c1ccccc1)C[Se]2 +COc1ccc(-c2nc3cnc4ccc(C)cc4n3n2)cc1 +O=C(C=Cc1ccc(O)cc1)CC(=O)C=Cc1cc(O)ccc1[N+](=O)[O-] +OC1(CCCc2ccccc2)CCN(CC2CN(CC3CCCCC3)CC2c2ccccc2)CC1 +COc1cc2ccc3c(OC)c(O)ccc3c2c(OC)c1O +COc1cccc(CCc2nnc(-c3ccc4[nH]cnc4c3)s2)c1Cl +CC(C1=C(CCN2CCCCC2)Cc2ccccc21)c1ccccn1 +COC1C(F)CN(C(=O)Cn2cc(C(C)=O)c3ccccc32)C1C(=O)NC(C)c1cccc(Cl)c1F +COc1ccc(-n2nc(CC(C(=O)O)c3cccc(Cl)c3)cc2-c2ccc(C)cc2)cc1 +CCOC(CC(=O)O)c1ccc(OC2CCCc3ccccc32)cc1 +CC1CN(Cc2ccccc2)c2ccccc2CN1C(=O)NCc1ccccc1 +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CCc3ccccn3)cc2n1 +CC(C)CCN(C(CO)CCCCNC(=O)N(Cc1ccccc1)Cc1cccc2c1OCO2)S(=O)(=O)c1ccc(N)cc1 +c1ccc2c(NCCCCCSc3c4c(nc5ccccc35)CCCC4)c3c(nc2c1)CCCC3 +O=C(NCC(O)CO)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2 +CCCNC(CC1CCCCC1)C(=O)NC(Cc1ccccc1)C(=O)NCc1ccc(CN)cc1 +Cc1cc(CN2CCCC2CO)ccc1C(=O)Cn1ccc(OCc2ccc(Br)cn2)cc1=O +COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc12 +O=C(NC1CCCCC1)c1ccc(S(=O)(=O)NCCc2c(-c3cc4ccccc4o3)[nH]c3ccccc23)cc1 +O=C(NC1c2ccccc2CC1O)C(O)C(O)C(O)C(Oc1ccccc1)C(=O)NC1c2ccccc2CC1O +COc1cc(OC)c(NC(=O)N(c2ccccc2)c2nnn(CCCCCCCCOC3CCCCO3)n2)c(OC)c1 +COCc1nc2c(NC(C3CC3)C3CC3)nc(C)nc2n1-c1ccc(OC)cc1 +O=C(Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12)N1CCOCC1 +CCOc1cc(=O)n(C)cc1-c1cc(N(CC2COCCO2)S(=O)(=O)CC)ccc1Oc1ccc(F)cc1F +COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(OC)c(NC(C(=O)O)C(F)(F)F)c2)c(OC)c1 +C=C(CN1CCOCC1)C(=O)Nc1ccc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1 +Cc1cc(Cl)cc2cc(C(=O)N3CC(N4CCCC4)C3)[nH]c12 +Cc1cc(OCc2ccc(NC(=O)C3CCN(C(=O)c4ccco4)CC3C(=O)NO)cc2)c2ccccc2n1 +CN(CCO)C1CCN(c2nc3ccccc3n2Cc2ccc(F)cc2)CC1 +O=C(O)CCC=CCC1C(F)CCC1NS(=O)(=O)c1ccc(Cl)cc1 +Cc1cccc(N2CC(=O)N3C(Cc4c([nH]c5ccccc45)C3c3ccc4c(c3)OCO4)C2=O)c1 +CCCCCCCCCCCCCCCCOP(=O)(O)OCC1OC(n2cc(C)c(=O)[nH]c2=O)CC1N=[N+]=[N-] +O=C(NC1CCCCCC1)c1cc(C=Cc2ccccc2)cn(Cc2ccc(F)cc2)c1=O +CC1(C)CC(c2cc(C(C)(C)C)c3c(c2)C(C)(C)CO3)=NO1 +Nc1nc(-c2ccccc2)c2c(n1)-c1cc(OCCN3CCCC3)ccc1C2=O +c1cc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)oc3c2)n2nccc2c1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCC(C(=O)c5ccc(Cl)cc5)CC4)nc3n2)cc1CO +CC(=O)NCc1cc(-c2ccc(C=CC(=O)O)cc2)cc(C23CC4CC(CC(C4)C2)C3)c1O +CCCc1c(OCCCCOc2ccc(C(C)(C)C(=O)O)cc2)ccc2c(-c3ccccc3)noc12 +O=C1CN(c2cccc3c2cnn3-c2ccccc2F)CCN1CC(=O)N1CCC(F)C1 +CCCc1c(OCc2cccc(Oc3ccc(-c4nn[nH]n4)cn3)c2)ccc(C(C)=O)c1O +Cc1ccc(N2CCC(N(c3ccc(C(F)(F)F)cc3)c3cccnc3)CC2)cn1 +Brc1ccc(CN2CCN(Cc3ccc4c(c3)OCO4)CC2)cc1 +O=c1nc(OCC2COCCO2)cc2n1CCc1cc(-c3ccc4[nH]ccc4c3)ccc1-2 +CCOC(=O)c1c(NCc2ccc3c(-c4nnn[nH]4)cc4ccccc4c(=O)c3c2)cc(C)nc1C +NC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +Nc1ncnc(N2CCC(c3nc(-c4cccc(F)c4)cn3CCN3CCCC3)CC2)c1Br +CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(c2ccccc2)c2nnn[nH]2)cc1 +COc1ccc2c(c1)c(CC(=O)NCCCCO)c(C)n2C(=O)c1ccc(Cl)cc1 +COc1ccc(CC(=O)NC(NC(=NC#N)Nc2c(F)cccc2F)C(C)(C)C)cc1OC +FC(F)(F)c1cc(COCC2(c3ccccc3)CCNCC2)cc(-c2nccs2)c1 +CN(C)C1CCN(c2cnc3ccc(Sc4nnc5c(F)cc(-c6cnn(C)c6)cn45)cc3c2)C1 +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(Cc3ccccc3OC)C2=O)cc1 +COc1ccc(C(=O)N2CCN(c3ccc4[nH]c5nc(O)nc-5cc4c3)CC2)cc1OC +CNc1c(Br)cnc2[nH]c(-c3cnn(C4CCN(C)CC4)c3)nc12 +COc1cc(-n2cnnc2)cc(Cl)c1C(=O)NCC(c1ccccc1)c1nc2cc(C)c(C)cc2[nH]1 +O=C1Cc2cc(-c3cc(Cl)ccc3Oc3cc(F)c(S(=O)(=O)Nc4ncns4)cc3F)ccc2N1 +CCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 +CC(C)S(=O)(=O)n1c(=O)n(Cc2nc3ccccc3n2CCCC#N)c2cnccc21 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3ccccc3)cc2)C(=O)C(C)C)c1 +O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)c1cccnc1Nc1cc(F)c(F)c(F)c1 +c1ccc(Cn2c(-c3ccc(OCC(CC4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 +Cc1c(C(=O)Nc2ccc(-c3ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc3)cc2)oc2cccc(N)c12 +O=C(O)CNc1ccc(-c2cnc(N3CCOCC3)c3nc(C=Cc4ccc5ccccc5n4)cn23)cn1 +O=C(O)c1csc(-n2nc(N3CCCCC3)c3ccccc32)n1 +Cc1cc(N(CCNc2ccnc3cc(Cl)ccc23)Cc2ccco2)nc(Cl)n1 +COc1cccc(CCN2CCC(CCc3ccccc3)CC2)c1 +CN(O)CCCc1ccc2c(c1)C(=O)c1ccccc1CO2 +CC1CCC2C(C)(COC(=O)c3ccco3)OC3OC4(C)CCC1C32OO4 +CCCCCCCCCC(=O)NC(Cc1ccc(C)cc1)C(=O)NC1C=CCCNC(=O)C=CC(C(C)C)NC1=O +COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O +COc1ccc(C(=O)Nc2nc(C)nc3cn(-c4ccccc4)nc23)cc1 +COc1ccc(C=C2CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC2=O)cc1 +O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(F)c(Cl)c3)cc2)cn1 +Cc1ccc2[nH]cc(C(=O)OCC34CCN(CC3)CC4)c2c1 +COCCOc1cc2ncnc(NC3=CC(=O)C(SC)=CC3=O)c2cc1OC +O=[N+]([O-])c1cc(CNCP(=O)(O)O)c2nc(O)c(O)nc2c1 +CCc1cn(C2CC(O)C(CNC(=O)Cc3ccccc3-c3ccccc3)O2)c(=O)[nH]c1=O +CS(=O)(=O)c1ccc(-c2cc(C=CCC[N+](=O)[O-])nn2C2CCCCC2)cc1 +Cc1cc(Cc2nc3n(n2)Cc2c(C)ncn2-c2ccccc2-3)on1 +NC(CC(=O)N1CCNCC1Cc1ccccc1)Cc1cc(F)ccc1F +COc1cc(OC)c2c(c1Cl)OC1(C2=O)C(OCc2ccccc2)=CC(=O)CC1C +O=c1ccc(-n2ccc3ccccc32)nn1CCCN1CCN(c2ccccc2Cl)CC1 +CC1(C)OC(=O)Nc2ccc(-c3ccc(C#N)[nH]3)cc21 +CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(OC)cc3)ccc2NC1=O +CCC(COc1ccc(C=C2SC(=S)N(CC(=O)O)C2=O)cc1OC(c1ccccc1)C(F)(F)F)c1ccccc1 +Cn1c2ccccc2c2c(NCCCN)nc3ccc(Br)cc3c21 +COc1ccc2c(c1)c1nn(CCOS(C)(=O)=O)c3cc4c(c(c13)n2C)C=CC(C)(C)O4 +CCc1nc2c(C)ccnc2n1C1CCc2cc(-c3ccccc3-c3nn[nH]n3)ccc21 +FC(F)(F)c1ccc2c(c1)nc(N1CCNCC1)c1cccn12 +Cn1cc(C(=O)NCCCO)c(Nc2ccc(I)cc2F)cc1=O +CCCCCCN1CCN(c2nc3ccccc3n2CCOCC)CC1 +Cc1c(C(C)C)c(=O)on1C(=O)N1CCN(c2ccccc2)CC1 +Cc1ccc(C2CC(c3cc(Br)ccc3O)=NN2C(=O)c2ccco2)cc1 +O=C(Nc1ccc2c(c1)OCC(CN1CCCC1)=C2)c1ccc(-c2ccc(F)cc2)cc1 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+C=CC(=O)Nc1cccc(Oc2nccc(Nc3cc(C)[nH]n3)n2)c1 +Cc1nc2sc(C(=O)NC(C)(C)C)c(N)c2c(C)c1Cl +O=c1ccoc2cc(OCCCN3CCN(CCCNc4c5c(nc6ccccc46)CCCC5)CC3)cc(O)c12 +O=C(c1cccc(O)c1)c1ccc(-c2cc(Cl)c(O)c(Cl)c2)s1 +COc1ccc(-c2cnc(N)nc2-c2ccccc2O)cc1C +Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)N5CCCC(O)C5)c[nH]4)c3)cc2F)c1 +NC(CC(=O)N1CCn2nnc(-c3ccncc3)c2C1)Cc1cc(F)c(F)cc1F +Cc1cc(C)cc(C(=O)N2CCC(NCc3ccnc4ccccc34)CC2Cc2ccc3ccccc3c2)c1 +CC(C)C(O)CC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2cc(O)ccc2[nH]1 +COc1cc(Nc2cc(C)nc3ccc(NC(=O)Nc4ccc(N(CCCl)CCCl)cc4)cc23)cc(OC)c1OC +Cc1cc(S(=O)(=O)NCCN(C)C)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +COc1ccc(-c2cc3c(C)nc(N)nc3n(C3CC(OCCO)C3)c2=O)cn1 +CC1CC(C)CN(c2cc(NC(C)C(Cc3ccc(Cl)cc3)c3cccc(Br)c3)ncn2)C1 +CN(NC(=O)CC(=O)NN(C)C(=S)c1ccc2ncccc2c1)C(=S)c1ccc2ncccc2c1 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccccc4Cl)no3)ccc21 +CC(C)=CCCC(C)=CCCC(C)=CCCC1(C)CCc2c3c(cc(C)c2O1)OCN(CCCCCCCCO)C3 +Fc1ccc(COCC2CCN(Cc3ccc(-c4ccccc4)cc3)CC2)cc1 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+O=c1n(CCc2ccc3ccccc3n2)nc2cccc(N3CCOCC3)n12 +FC(F)(F)c1cnc(Nc2nc(N3CCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cn1 +Cc1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O +Cc1c[nH]c2ncc(-c3cc(C4CCOCC4)n(C4CC(F)(F)C4)n3)cc12 +CSC1C(C)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)CC1N +COC(=O)CCCC=C(c1cc(C)c(OC)c(C(=O)OC)c1)c1cc(Cl)c(OC)c(C(=O)OC)c1 +O=C(NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ccccc2CNCCCN2CCCC2=O)CC1)C1Cc2ccccc2CN1 +O=C(O)C(Cc1cscn1)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc(Cl)c(Cl)c3)n[nH]c2C1(C)C +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(C3C=CC(=O)N=C3)nc2n1 +CC(C)N1CCN(C(=O)c2ccc3[nH]cc(CN4CCOCC4)c3c2)CC1 +C=C(c1cc(Cl)c(Cl)cc1OCC(O)CNC(C)C)n1ccnc1 +O=CN1CCN(c2cc(-c3ccc(Sc4ccc5c(c4)OCCO5)c(C(F)(F)F)c3)ccn2)CC1 +COc1ccc(NC(=O)c2ccc(F)c(Nc3ncnc4cnc(N5CCN(CC6CC6)CC5)nc34)c2)cc1C(F)(F)F +COc1ccc(CC(=O)O)cc1-c1ccc(S(C)(=O)=O)c2c1CN(C(=O)OCc1ccccc1)CC2 +COc1ccc(C2C3c4c(c5ccccc5[nH]c4=O)OC(C)(C)C3C2C2CC2)cc1OCCCO +CCc1onc(-c2ccccc2Cl)c1C(=O)N(CC)c1ccc(Cl)cc1 +CCc1cc(CN2CCC(C(=O)NC(C)(C)C)CC2)cc(NC(=O)c2cncc(C)c2)c1 +Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)c(C(F)(F)F)c1 +Cc1noc(=O)c2ccc(NC(=O)C(O)(Cc3ccccc3)CC(C)(C)c3cc(F)ccc3O)cc12 +CCCC(NC(=O)CCc1cc(F)cc(F)c1)C(=O)Nc1ncc(C(C)CCCC(C)(C)OC)s1 +Cc1nc2ccccc2c(=O)n1N=Cc1ccc(O)cc1O +CCCCN1C(=O)C(=CNC(C)(C)CO)C(=O)c2cccc(C)c21 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1C +O=C(Nc1cc2cccnc2cc1OC1CCNCC1)c1cnn2cccnc12 +O=C(c1cccc2occc12)c1cn(CCN2CCOCC2)c2ccccc12 +COc1ccc(S(=O)(=O)c2cc(C)c3ncc(C(N)=O)c(Nc4cccc(OC)c4)c3c2)cc1 +CC(C)c1ccccc1Sc1ccc(-c2ccnc(N3CCN(C=O)CC3)c2)cc1C(F)(F)F +O=c1[nH]c(CCCCCCCCCCCCc2nsc(=O)[nH]2)ns1 +CCNC(=O)Nc1ccc(-c2cc(N3CCOCC3C)c3ncn(COCCOC)c3n2)cc1 +COC(=O)c1cc(OC)cc(OC)c1C1CC12C(=O)Nc1ccc(Cl)cc12 +CC(C)CC(NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(N)=O +Cn1c(CC(=O)N2CC(C)(C)c3c(F)cccc32)nc(N2CCOCC2)cc1=O +CNC(=O)c1cn(C)c2c1CCc1cnc(NC3CCN(S(=O)(=O)c4ccccc4)CC3)nc1-2 +CCCCCOC(=O)CCC(=O)Nc1nnc(S(N)(=O)=O)s1 +O=C(NCc1ccc(S(=O)(=O)c2cccnc2)cc1)c1cc2cnccc2[nH]1 +CC(=Cc1cc(F)c(Oc2ccc(S(=O)(=O)NCCOCCOCCOCCN)cc2)c(F)c1)C(=O)N=C(N)N +Cc1c(C(C)C)c(=O)on1C(=O)N(C)c1ccccc1 +COc1cc(-c2onc3c2CCCN3Cc2cc(F)cc(F)c2)ccc1-n1cnc(C)c1 +O=C(NC(Cc1ccc(NC(=O)c2ccnc3ccccc23)cc1)C(=O)O)c1ccccc1Br +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4cccnc4)nc23)N1 +O=C(N1CCC(F)CC1)N1CC(OC(c2ccc(Cl)cc2)c2cccnc2Cl)C1 +COc1cccc(-c2c(C(=O)N[n+]3c(C)cc(C)cc3C)[nH]c3ccc(S(N)(=O)=O)cc23)c1 +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OCC(CO)c6ccccc6)ccn5)n4)ccc3[nH]2)CC1 +N#Cc1cc(-c2ccnc(Nc3cnn(C4CCC(O)CC4)c3)n2)ccc1OCC1CCC1 +C[S+]([O-])c1ccc(-c2cnn3ccc(-c4cccc(S(=O)(=O)C5CC5)c4)cc23)cc1 +O=C(Cc1cccc(OC(F)(F)F)c1Cl)NC1COc2ncccc21 +O=C(NC1CCCCC1O)c1cnc(OCC2CC2)c(-c2ccc(Cl)c(Cl)c2)c1 +COc1ccc(S(=O)(=O)C(CCCC(=O)N2CCCc3ccccc32)CC(=O)NO)cc1OC +CCCCNC(=O)C(C)CC(O)C(N)CC(Cc1ccc(OC)c(OCCOC)c1)C(C)C +COc1cccc(C(C)=NNc2ncc(Cl)c(Nc3cccc(NC(=O)C=CCN(C)C)c3)n2)c1 +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(F)c3)cn2CCN2CCCC2)CC1 +O=C(CCCCCCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1)NO 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+O=C(O)CN(CCOc1ccc([N+](=O)[O-])cc1)CCc1ccc([N+](=O)[O-])cc1 +Oc1ccc(-c2ccc3c(c2)OCO3)cc1CNCC1(N2CCCCC2)CCCCC1 +CN(CCCCCCCCCOc1ccc2c(=O)c3ccccc3oc2c1)Cc1ccccc1 +COc1cc(-c2nnc(-c3ccc(O)cc3O)s2)cc(OC)c1OC +CCN(CC)CCCC(C)Nc1nc2ccccc2c2c1c1ccccc1n2C +COc1cc(O)cc2c1C(Br)=C(c1ccc(O)cc1)C2=O +CC(=O)N1CCN(c2ccc3cc2COCC=CCOCc2cccc(c2)-c2ccnc(n2)N3)CC1 +CC1C(c2ccccc2)C1(NS(=O)(=O)N1CCN(c2ccc(Cl)cc2)C(CO)C1)C(=O)O +CN1CCCC(CC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cccnc43)CC2)C1 +CCn1c(=O)ccc2c(-c3cnc(-c4cccnc4)s3)n[nH]c21 +COc1cccc(OC)c1-c1cc(C(=O)NC(C(=O)O)C2CCCCC2)nn1-c1ccnc2cc(Cl)ccc12 +N#CC1(C(=O)N2CC(CF)C(Nc3c(C(N)=O)cnn4cc(-c5cnn(C6CC6)c5)nc34)C2)CC1 +Cc1ccc(N(C(=O)NCCCN2CCC3(CCc4ccccc43)CC2)c2cccc(F)c2)cc1 +Cn1c(=NNC(=O)c2ccco2)sc2cc(OC(F)(F)F)ccc21 +COc1ccccc1N1CCN(CCCCn2cc(-c3ccc(N)cc3)nn2)CC1 +COc1cccc(-c2c(C)n(Cc3ccccc3F)c3nc(C(C)(C)C)c(CN(C)CCc4ccccc4)n3c2=O)c1 +Cc1ccc(NC(=O)c2ccc(CN3CCN(CCO)CC3)cc2)cc1-n1cc(-c2cccnc2)cn1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNCc2cccc(I)c2)c1 +CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(CC)c1=O +c1cc2c(ncn3nnc(C4CCC(CNCC5CCCO5)CC4)c23)[nH]1 +OC(CN1C2CCC1CC(c1ccccc1)C2)c1cccc(Br)c1 +Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCCCCC1 +O=c1c2ccccc2ncn1CCCCN1CCN(c2ccc(Cl)cc2)CC1 +CC(NC(=O)C1(NC(=O)C(F)(F)F)CC1)c1ccc(-c2cccc(Cl)c2-c2nnn(C)n2)cc1F +NS(=O)(=O)Nc1ccc(S(=O)(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1cc(C#N)cnc1C(=O)Nc1ccc(F)c(C2(C(F)F)COCC(N)=N2)c1 +CC(C)(C)CCC1(C(=O)c2cc(Cl)c(Cl)s2)CCNC1 +C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1 +CCCN(Cc1sc(Nc2c(Br)cc(Br)cc2Br)nc1C(F)(F)F)CC1CC1 +CCCCCCCCCCCCCC(=O)OC12C(O)C(C)C3(O)C(C=C(CO)CC4(O)C(=O)C(C)=CC43)C1C2(C)C +CCc1cccc(N(C)C(=N)Nc2cc(SC)cc(Br)c2Cl)c1 +Fc1ccc(Cc2nnc3ncc(-c4cccs4)nn23)cc1 +CN1C2CCC1CC(N(c1ccccc1)c1ccc(C(=O)O)cc1)C2 +CNc1nc(Nc2cc(OC)c(C(=O)N3CCCC3)cc2Cl)ncc1Cl +Nc1nc(NCC(O)c2ccccc2)nc2c1ncn2C1OC(CO)C(O)C1O +CCS(=O)(=O)c1ccc2[nH]c(Oc3cccc(-c4ccccc4)c3)nc2c1 +Cn1ncc2cc(-c3nn(C(C)(C)C)c4ncnc(N)c34)ccc21 +Cc1ccc(CN2C(=O)N(Cc3ccc(C)cc3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)cc1 +CC(C)(C)c1ccc(-n2cc(-c3ccc(S(N)(=O)=O)s3)nn2)cc1 +O=C(Nc1ccc(C(F)(F)F)cc1Cl)N1CCC2(CCc3cccc(Cl)c3O2)CC1 +CCNc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(CO)c12 +Cc1c(Cc2ccccc2Cn2ccnn2)c2c(n1CC(=O)O)CCNC2=O +Cc1sc(-c2ccc3c(c2)OCO3)nc1CCOc1ccc2c(c1)CCC2CC(=O)O +COc1ccccc1N1CCN(CCCCC(Oc2ccc(C(=O)Nc3ccccc3OCCCC(=O)O)cc2)c2ccccc2)CC1 +NCc1ccc(C(=O)NCC(=O)N2CCN(CC(=O)O)C(=O)C2CC(=O)O)cc1 +COc1cccc(C(=O)N=c2sc(C(C)(C)C)c(C)n2CC2CC2)c1 +O=C(CN1CCCCC1)Nc1cnc2c(c1)nc(O)c1ccccc12 +Cc1cc(-c2n[nH]c3cc(NC(=O)N4CCN(c5ccc(F)cc5)CC4C)ncc23)ccn1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(OCC(C)C)c2)c1 +CC1CN(c2sc(C(F)(F)F)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cc(C2CCN(C)CC2)cn1 +O=C(c1ccc(F)cc1-c1ncccn1)N1C2CCC1C(Nc1ccc(C(F)(F)F)cn1)C2 +O=C(O)c1ccc(-c2c(C#Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)s1 +COc1ccc(N=c2oc3cc(O)ccc3cc2C(=O)NCCCO)cc1 +Fc1ccc(-n2cc(CCCCN3CCC4(CC3)OCc3c(F)cccc34)c3ccccc32)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)C4CCCC4)ncc3Cl)C2)cc1 +O=c1[nH]c(N2CCC(N3CC=C(c4ccccc4)CC3)CC2)nc2ccccc12 +CN(C)C1Cc2ccc(O)c3c2C2C(O3)C(=O)CCC21O +Cc1cc2nc(C3CCOC3)n(-c3ccc4c(N)nc(N)nc4c3)c2cc1C +Fc1ccccc1-c1n[nH]c2cnc(-c3cnccc3OCC3CCCNC3)cc12 +CCN(C(=O)c1ccccc1)c1ccnc(NC(C)c2ccccc2)n1 +NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(C4CCNC4)c3)ncc2Cl)CC1 +Cc1cc(C2CCCN(C(=O)c3ccc4ccccc4c3)C2)n2ncnc2n1 +Cc1[nH]c(Br)c(C)c1-c1ccnc(Nc2ccc(F)cc2)n1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2cnc3ccccc3c2)n1 +Nc1ccc2[nH]c(C(=O)NCc3ccc(C(=O)Nc4ccccc4N)cc3)cc2c1 +CC(C)=CCN(Cc1cc2c(=O)n(C)c(C)nc2cc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +CCc1cc(CC)nc(OCCCn2c3c(c4cc([N+](=O)[O-])ccc42)CCCC3)n1 +CCCCc1nc(-c2nc(C)c[n+]([O-])c2C)cn1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c(-c3cccs3)nn(CCC3CCC3)c1=O)N2 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(OC(F)(F)F)c1 +CN1CCc2nc(C(=O)Nc3ccc(C(=O)O)cc3CNC(=O)c3ccc(Cl)s3)sc2C1 +Nc1nc(C=Cc2ccccc2)nc2cn(-c3ccccc3)nc12 +CCC(N)C(=O)NC1CCCCC2CCC(C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O +CCc1ccc(NC(=O)Nc2cc(C(C)(C)C)sc2C(=O)NC)cc1 +O=C(O)COCC1CCC(COC(=O)N(c2ccccc2)c2cccc(Cl)c2)CC1 +CCCCC(NC(=O)c1ccc(CN=C(N)N)cc1)C(=O)NC(CC(C)C)C(=O)NC1CCCCC1c1cccc(Cl)c1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)ncnc1OCC#CCO +CCOC(=O)CCc1ccc(-c2ccc(OC)cc2)n1-c1ccc(C(=O)NCCO)cc1C +CC(C)C(NC(=O)c1cccnc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)C2(CC2)C1 +COc1cncc(C2=CCC3C4CCN5C(=O)CCCCC5(C)C4CCC23C)c1 +N#Cc1ccc(OCCCN2CCC(C(O)(c3nccs3)C3CCCC3)CC2)cc1 +Nc1ccc(Nc2cc(=O)oc3c2ccc2ccccc23)cc1 +Cc1ccc(S(=O)(=O)N(C)C(C)(C)C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)cc1Cl +CC1=CCC2C(C1)c1c(O)cc(CC=CCCCO)cc1OC2(C)C +CC1(C)CC(O)CC(C)(CNc2cc(Cl)cc(C(F)(F)F)c2)C1 +CC(C)c1[nH]nc2c1C(c1cccnc1OCC(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O +COc1cc(OCc2nc(-c3ccnc(F)c3)sc2C)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +COc1ccc2ccn(CCn3cc(NC(=O)c4ncoc4-c4cccc(C)c4)cn3)c2n1 +CCOc1cc(C=C(C#N)c2nc3ccccc3[nH]2)ccc1OCc1ccccc1C#N +CSc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 +CN(C)CCN(C)Cc1ccc2n1Cc1ccccc1N(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1Cl)C2 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+Cc1cc2c(cc1C(=O)N=C(N)N)S(=O)(=O)CCC2 +CONC(=O)c1ccc(F)c2c(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12 +COc1cccc(Nc2ccc(NC(=O)C3CC3)cc2)c1 +C=CCCCCCCC(OC(=O)N(CCCCC=C)CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)c1ccccc1 +Cc1cccc(NC(=O)NC2CC(c3ccccc3C)CC(c3ccccc3)N(CC(=O)Nc3ccccc3Cl)C2=O)c1 +N#CCc1cccc(C#Cc2ccc(CCC(=O)O)cc2)c1 +Cc1ccc(C(NC(=O)c2ccccc2O)C(=O)Nc2c(C)cccc2C)s1 +O=C(Cc1ccc(Br)cc1)NC(CCS)C(=O)NC(Cc1ccccc1)C(=O)O +CCCCN(C)c1ncc(-c2ccccn2)c(NC2CCC(O)CC2)n1 +COc1ccc(CN2CCC(n3c(O)nc4ccccc43)CC2)c(Cl)c1 +CN1CCCN(c2c3cc(Cl)ccc3nc3c2c2ccccc2n3C)CC1 +CCCCc1nc(Cl)c(COC)n1Cc1ccc(NC(=O)c2ccccc2S(=O)(=O)O)cc1 +COc1cccc(-c2cc(-n3cc(CNCC(C)C)c4ccccc43)c(C)cn2)c1 +O=C(Nc1nc2cc(Br)ccc2[nH]1)c1cc2ccc(Br)cc2[nH]1 +COc1cc(Cc2cnc(N)nc2N)cc(OCCCC(=O)O)c1Br +COCc1cc2cc(c1)C(=O)NC(C(O)CNC(C)(C)c1cccc(C(C)C)c1)Cc1cccc(c1)OCCCCN2 +COc1ccc(-c2ccc(Cl)c(C(=O)CC(=O)C(=O)O)c2)cc1 +C#CCn1c(-c2ccccc2)nc2sc3c(c2c1=O)CCC3 +O=C(NCCc1ccc(Cl)cc1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CN1CCN(c2ccc3[nH]c(-c4c(N)c5cc(C(=O)NCc6ccccc6)ccc5[nH]c4=O)nc3c2)CC1 +CCOC(=O)c1c(N(CC)Cc2ccccc2)nc2ccccc2c1-c1ccccc1 +O=C1CC(CCc2ccccc2)(c2ccccc2)OC(O)=C1Sc1ccccc1C1CCCCC1 +CC(C)c1ccc(Cc2cc(C(=O)C(=O)Nc3cccnc3)c3ccccn23)cc1 +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5cncn5c4)c3c2)C1 +CCc1cc2cnc(Nc3ccc(N4CCC(O)CC4)cn3)nc2n(C2CCCC2)c1=O +CCCn1c(=O)[nH]c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)cc21 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(-n3ccnc3)cc2)cc1 +N=C(N)N1CCCC1Cc1nc(-c2ccc(Nc3nc(-c4cccc(C(F)(F)F)c4)cs3)cc2)no1 +CCC(CO)Nc1nc(NCc2cccc(O)c2)c2ncn(C(C)C)c2n1 +COc1ccccc1N1CCN(CCNC(=O)C2CC3CCCC3C2)CC1 +CCc1ccnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4ccnc(N)c34)cc2)c1 +COc1ncccc1-c1csc2ncnc(N3C4CCC3CC(NC3CCC3)C4)c12 +Cc1cc(NCP(=O)(O)O)cc(C)c1Cc1ccc(O)c(C(C)C)c1 +CCCNC(=O)N1C(C#N)C(c2ccc(C#Cc3ccc(F)cc3)cc2)C1CO +O=C(NCc1ccno1)c1csc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)n1 +COc1ccc(Oc2cccc(C(CC(=O)NO)S(=O)(=O)c3ccc(OC)c(OC4CCCC4)c3)c2)cc1 +CC(C)n1nc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c2cc(OCc3ccccc3)ccc21 +COc1ccc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)cc1Cl +O=C(Nc1c(Cl)cccc1Cl)NC1CCC(Oc2ccc(F)cc2)CC1 +O=C(Nc1ccccc1)c1ccc([N+](=O)[O-])o1 +O=C1CN(C2CCCc3c(OCc4ccncc4)cccc32)C(=O)N1C1CCCCC1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CCC2)C1c1ccc(C#N)cc1-c1ccco1 +COC1C(OC(N)=O)CCC2(CO2)C1C(C)=CCC=C(C)C +O=C1CCc2ccc(OCC#CCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1 +COc1ccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 +CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OC(=O)CN +Cc1cc(CC2CNCC2NCCNCCc2cccc(F)c2)cc(N)n1 +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)NC(C)C)c1ccc(Br)s1 +Cc1nc(N2CC3C(=O)N(C)C(N)=NC3(c3cccc(C#N)c3)C2)nc(C2CC2)c1F +O=C1CC2CCCC3(CC(CC(CCCCc4ccccc4)O3)OC(=O)CC(CO)O1)O2 +O=C(CCc1c[nH]c2ccccc12)N1CC2CCCN2CC1Cc1ccccc1 +Cc1[nH]c2ccccc2c1Cc1ccc(C(=O)NC2CNCC2C(=O)NO)cc1 +O=C(Cc1ccccc1Cl)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 +CC(C)Nc1c(C(N)=O)cnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc12 +COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(C3CCC(O)CC3)sc2c1 +COc1cn(-c2ccc3c(c2F)C(C)(C)C(=O)N3C)nc(-c2ccnn2-c2ccccc2)c1=O +Cn1c(N2CCOCC2)cc(OCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O +CON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(C)cccc3C)CC2)CC1 +COc1cc(CC#Cc2cnc(N)nc2N)cc(OC)c1OC +CN(C)c1cccc(OCCCn2cnc(-c3ccccc3)c2)c1NC(=O)NC1CCCC1 +COc1ccc(C2CCN3C(=O)OCC23)cc1OC1CCCC1 +Cc1c(Cn2ncc(N3CCNCC3)cc2=O)cccc1NC(=O)c1ccc(-c2ccccc2)cc1 +O=C(O)c1cccc2nc(-c3c(F)c(F)c(-c4cccc(OCc5ccccc5)c4)c(F)c3F)[nH]c12 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCCC4)ncn3)c2c1 +c1n[nH]cc1-c1cnc2ncc(-c3cn[nH]c3)n2c1 +CC1(C)CN(c2ccc(C#Cc3ccccc3)cn2)C(=O)CO1 +O=C(C(=O)N1CCCC1C(=O)OCCCc1ccccc1)C1CCCCC1 +CCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NC4CCC4)ccc3C)c2c1C +O=c1[nH]c(Cc2ccccc2-c2noc(C(F)(F)F)n2)nc2c1cnn2C1CCOCC1 +COC(=O)Nc1ccc2c(c1)NC(=O)C(C)CCCC(N1CCC(c3cncc(Cl)c3)=CC1=O)c1cc-2ccn1 +CC(C)(C)C(=O)Nc1ccc(N2CCN(C(=O)c3cccc(F)c3)CC2)c(Cl)c1 +COc1cc(-c2ccc3ncc(C(C)=O)c(Nc4cccc(CCN(C)C)c4)c3c2)cc(Cl)c1O +Cc1ccccc1S(=O)(=O)N(C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CCOc1ccccc1-c1nc(O)c2nc3cccc(CC)n3c2n1 +CC1=CC(=O)C(O)C2(C)C1CC1OC(=O)C(OC(=O)CC3(O)CCC3)C3C(C)C(O)C4(O)OCC13C42 +COc1ccc(-n2c(S)nnc2-c2csc(NC(=S)Nc3ccccc3)n2)c(OC)c1 +CC1CN(Cc2c[nH]nc2-c2cc(C(=O)NCCO)c[nH]2)CCN1c1ccc(C(F)(F)F)cn1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C(C)C)nc1Cl +COc1ccc(CCCN2CCN(C)CC2)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12 +CCOC(=O)c1ccc(NC(=O)CCc2nc(-c3ccccc3Cl)no2)cc1 +CC1(C)CCN(c2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)c2ccccc21 +Cn1c(=O)ccc2c(NC(=O)NC3CC(CF)(CF)Oc4c(F)cccc43)cccc21 +Cn1cnc2cc(-c3ccc(C(C)(C)N)cc3)nc(N3CCC(CO)C3)c2c1=O +CN(C)C1CCC(n2cc(C(N)=O)c(Nc3ccc(OC(F)(F)F)cc3)n2)C(C#N)C1 +NC1CCCN(c2ccccc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)C1 +COc1n[nH]c2c(F)c(NC(=O)NC(C)c3ccccc3)ncc12 +CC(O)CNc1nc(NCc2ccc3c(c2)OCO3)c2nc(NCC(C)O)nc(NCc3ccc4c(c3)OCO4)c2n1 +Cc1ccc(S(=O)(=O)Nc2ccc(CN3CCN(C(=O)c4cccc(C#N)c4)CC3)cc2)cc1 +CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc4c(C(=O)NC5CCC5)cccc4c3)n2)c1 +CC(Nc1nc(Cl)cc(N2C(=O)OCC2C(C)O)n1)c1ccc(C(C)(C)F)cc1F +CC1(c2nc(NC(=O)c3ncc(OCF)cc3Cl)ccc2F)N=C(N)OCC1(F)F +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)Nc3c(F)cccc3F)nc12 +COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2C(C)C)c1 +NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4c3ncn4C3OC(CO)C(O)C3O)cc2)cc1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccc(NS(=O)(=O)O)cc3)o2)C(C)O)c(C)c1Cl +COc1cc2c(cc1OC)-c1c(-c3cnc(N4CCOCC4)s3)ncn1CC2 +CC(NC(=O)C1C(C(=O)NCCCCN2CCCC2)C2C=CC1C21CC1)c1ccc(Br)cc1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)cc2c3cccc(C=O)c3nc-2c1O)C(=O)C(F)(F)F +COc1ccc(Br)cc1C(O)C(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)C(C)C +CCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +CCN(CCCc1ccccc1)CCC(O)(P(=O)(O)O)P(=O)(O)O +Cc1nc(C#Cc2cncc(-c3cccc(C#N)c3)c2)cs1 +CN1CCCC1COc1ccc(C(F)(F)F)cc1C(=S)N=c1sc(C(C)(C)C)cn1CC1CCCO1 +CCCCCCCCCCCCCCCC(=O)C1=C(O)C(CO)OC1=O +Cn1cc(-c2cnc3ccc(N(CC4CC4)c4cccc(C#N)c4)cc3n2)cn1 +OC1COCC1Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cccnc1 +CCc1sc(NN=Cc2ccccc2C(=O)O)nc1-c1ccccc1Cl +C=CC=CC(C)C(OC(N)=O)C(C)C(O)C(C)CC(C)=CC(C)C(O)C(C)C=CCCc1sccc1C +CC1OC(=O)C2CC3CC(O)CCC3C(C=Cc3ccc(-c4cccc(Cl)c4)cn3)C12 +COc1ccc(C2=C(C(=O)O)C(c3ccc(OC)cc3OC)Oc3ccc(OC(C)C)cc32)cc1 +CN(CC1CCCCN1C(=O)Cc1ccc2c(c1)CCCC2=O)C1CCCC1 +Cc1ccc(-c2cccc3c(=O)n(-c4ccc(N5CC(C)OC(C)C5)nc4)cnc23)cc1 +COc1ccc(OCC(O)CN2CCN(c3ccccc3C)CC2)c(C(C)=O)c1 +CCc1c(Sc2ccccc2)n(CC=Cc2ccc([N+](=O)[O-])s2)c(=O)[nH]c1=O +COC(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2C2CCN(c3ccccn3)CC2)C1 +Cc1nnsc1C1=NNC(=O)C1=Cc1cn(C)c2ccc(F)cc12 +CC(C)CC(N)C(=O)N1CCc2nc(Cc3ccc(F)cc3Cl)sc2C1 +CN(C)CCNC(C(=O)NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccs1 +Cc1nc(NC2CCOc3ccccc32)cc(-c2ccc3occ(C)c3c2)n1 +O=C(NO)c1cc2c(s1)CCN(C(=O)C1CCCCC1)C2 +Cc1cccc2c(OCc3ccccn3)nn3c(-c4ccccc4)nnc3c12 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Cc3ccc(F)cc3F)c(F)c2)CC1 +COc1cc(-c2nn(C3CCC(N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)Nc1ccccc1 +CC(C)(C)OC(=O)NCCCNC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +O=C(c1cc2ccc(O)cc2[nH]1)N1CCC(CCc2ccccc2)CC1 +O=C(NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1)C(O)C(F)(F)F +O=C(O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2ncccc12 +O=c1c(F)cc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n1C1CCCC1 +CN(CC(CCN1CCCC(n2c(O)nc3ccccc32)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +COCCOc1ccc2cc1CN(C)CC=CCCOc1cccc(c1)-c1ccnc(n1)N2 +Cn1c(-c2ccc(-n3ccnc3C(F)(F)F)cc2Cl)nnc1C1(c2ccc(Cl)cc2)CCC1 +CC(C)=CCn1c2c(ccc1=O)C(NCCc1ccc(Cl)cc1Cl)CCC2 +COc1ccc(-n2cc(-c3ccc4c(c3)C(=O)NCCO4)c(N)n2)cc1 +CCCc1c(OC)ccc2c(-c3cnc(-c4ccc(C(=O)O)c(F)c4)s3)n[nH]c12 +CCCCCC1=NN(C(=O)c2cccc3ccccc23)CC1c1ccccc1 +CN(C)Cc1ccc(CSCCCCSCc2ccc(CN(C)C)o2)o1 +CC(C)(C)c1nc2c(s1)CCc1nc(NC(=O)N3CCC4CC43C(N)=O)sc1-2 +CP(C)(=O)c1ccc(Nc2nc(C3CCCC3)nc3c2ncn3CCc2cccc(O)c2)cc1 +NS(=O)(=O)c1ccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc1 +CC(C)(C)S(=O)(=O)NCC1CCC(Nc2nc(-c3ccc(F)cn3)no2)CC1 +COC(=O)C1=C(CN2CCOCC2(C)C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Cl +CCCCCn1c2ccccc2c2cc(C(=O)N3CCCCC3)ncc21 +CN1C(=O)C2C(N=C(N3CCCC(N)C3)N2Cc2ccccc2)N(C)C1=O +COC(=O)N1CC2Cc3[nH]ncc3C(C1)N2S(=O)(=O)c1ccc(Cl)cc1 +c1cncc(-c2nc(NC3CC4CCC3C4)c3ccccc3n2)c1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-c2ccccc2)c1 +Cc1cn(C2CC(N=[N+]=[N-])C(COP(=O)(O)OCCOc3cccc4ccccc34)O2)c(=O)[nH]c1=O +COCc1cc(F)ccc1C1CCCn2nc(C=Cc3ccc(-n4cnc(C)c4)c(OC)c3)nc21 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OCC1CN(C)CCO1 +C#CCN1C(=O)C(C)(C)c2cc(-c3ccc(C#N)n3C)cc(F)c21 +CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2cc(F)cc(C(F)(F)F)c2)CC1 +CCCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)OCC3)cc1 +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(OCc2cn(Cc3ccc(Cl)cc3)nn2)c1 +CC1(C)C(=O)N(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c21 +O=c1c(Br)cn(C2OC(CO)C(O)C2O)c(=O)n1CCCCCCCCP(=O)(O)O +CNc1ccc(-c2cc3ncn(C)c(=O)c3c(NCCCO)n2)cc1S(C)(=O)=O +CC(=O)NCCNc1nc(-c2ccccn2)nc2c1CN(Cc1ccc(F)cc1)CC2 +Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccccc3OC(F)(F)F)c2)s1 +N=C(N)c1ccc(COc2c(Br)cc(C(=N)N)cc2Br)cc1 +CNc1cc(N2CCCNCC2)ccc1S(=O)(=O)c1cccc(F)c1 +Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)CC(C)(C)CC(=O)O)ccc3n(C)c12 +CC(C)Nc1ncnc2c1ncn2C1OC(COS(=O)(=O)NC(=O)c2ccccc2O)C(O)C1O 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+O=C1C=C(OCc2ccccc2)C(O)(Cc2ccccc2)N1CCCNc1ccnc2cc(Cl)ccc12 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3C(=O)OC(C)C)c1C +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3cc(Cc4ccccc4)on3)CC2)C(c2ccccc2)C1 +CC1CN(c2ccc3c(N4CC(C)NC(C)C4)c(C#N)c4nc5ccccc5n4c3c2)CC(C)N1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)NCc3cccc(F)c3)[nH]c12 +C=C(c1ccc(CC)cc1)C1CNC(C(=O)O)C1CC(=O)O +CCN(C(=O)c1cccnc1C(=O)O)C1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +O=C(N1CCCCC1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 +Cc1cc(-c2ccc(F)c(C)c2)c(CCP(=O)(O)CC(O)CC(=O)O)c(C(C)C)c1 +Cn1cc(NC(=O)c2ccc3cnc(NC4CCCCNC4)nn23)c(C(F)F)n1 +Cn1c(-c2ccccn2)c(C2CCCCC2)c2ccc(C(=O)NC(C)(C)C(=O)Nc3ccc(C=CC(=O)O)cc3)cc21 +Cc1ccn2nc(SCc3nc(-c4ccccc4)cn3C)nc2c1 +Cc1cc(C)[n+](CC(=O)Nc2cc(Cl)c(S(N)(=O)=O)cc2S(N)(=O)=O)c(C)c1 +O=C(CN1C(=O)C2(OCCCCO2)c2cc(Cl)ccc21)Nc1ccc(C(=O)NO)cc1 +C=C1ON=C2N1C(C)=CSC2(O)c1ccc(Br)cc1 +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncnc2ccc(C(=O)O)cc12 +CC#CCOc1ccc(S(=O)(=O)N2Cc3cc(N4CCOCC4)ccc3N(C(C)=O)CC2C(=O)NO)cc1 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+N=C(NCC(O)CO)c1c(O)nsc1Nc1ccc(Nc2ccc(Br)cc2)cc1 +CC(C)CC(NC(=O)c1cc(COc2ccccc2)ccc1CCC(=O)O)c1ccc(Cl)cc1 +CCNC(=N)c1ccc(C2=NOC(CC(=O)NCCC(=O)O)C2)cc1 +Nc1cnc(-c2ccc(C3CCC3)c(OCC(O)Cn3ccncc3=O)c2F)cn1 +CCOC(=O)c1ccc(NC2CCN(c3nnc(Cc4ccccc4)c4ccccc34)C2)nc1 +CCN(C(=O)c1cc(C)ccc1-n1nccn1)C(C)Cc1noc(-c2ccc(F)cn2)n1 +O=C(NCC=CCN1CCN(c2ccccc2OCCF)CC1)c1cc2cc(O)ccc2[nH]1 +O=C(Nc1ccc(C(=O)N2CCN(c3cccc(F)c3)CC2)cc1)N1Cc2ccccc2C1 +N=C(N)Nc1ccc(OC2CC(Oc3ccc(NC(=N)N)c4ccccc34)C(NC(=N)N)CC2NC(=N)N)cc1 +O=C1C(Br)=C(N2CC2)C(=O)C(Br)=C1N1CC1 +O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3ccccn3c2-c2ccnc(Nc3ccc(CCN4CCOCC4)cc3)n2)c1 +Cc1ncnc(C)c1C(=O)NCCC(C)N1CCC(N2C(=O)N(C3CCCCC3)CC2c2ccc(Br)cc2)CC1 +Cc1cc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)cn2CC(CF)O3)no1 +O=S(=O)(c1cnc2ccccc2c1)N1CCC(CN2CCN(c3ccc(Cl)cc3)CC2)CC1 +NC(=O)c1nc(-c2ccncc2)sc1NC(=O)c1ccc(CN2CCOCC2)cc1 +Oc1cccc(-c2cc(-c3cccc(Cl)c3)nc3c2oc2ccccc23)c1 +COc1ccc(NCCNC(=O)C(Cc2ccc3ccccc3c2)NC(=O)c2cccc(C)c2)cc1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC4COC(c5ccccc5)OC4)c3)s2)nn1 +O=C(C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2)Nc1ccc(C(F)(F)F)nc1 +Nc1ncc(-c2ncccc2C(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)(COC(F)F)CC1 +COc1cccc2c1nc(N1CCNCC1)n2Cc1ccccc1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4C(C3)C4(Cl)Cl)n2)cc1OC(F)F +O=C(NN1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Br +c1ccc(CNc2ccc3[nH]nc(-c4nc5cc(N6CCC(N7CCCCC7)CC6)ccc5[nH]4)c3c2)cc1 +O=C(NC(Cc1ccccc1)C(=O)NNC(=O)c1ccccc1)OCc1ccccc1 +O=C(Nc1cc(-c2ccc3c(c2)OCO3)nc(-c2ccccc2)n1)C1CC1 +CC1CCC(Oc2cc(C(F)(F)F)nc3ccccc23)CN1C(=O)c1ccccc1-n1nccn1 +NC(=O)CC(NC(=O)CNC(=O)CNC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +COc1cc(N(O)O)ccc1S(=O)(=O)Nc1cnc2ccccc2c1 +O=S(=O)(c1ccc(F)cc1)N1CC2CC1CN2CCOc1ccccc1-c1ccccc1 +Cc1nc(C2CCCO2)c2c(N3CCc4cnn(C)c4C3)ncnn12 +Cc1cc(CN2CCCC2)ccc1C(=O)Cn1ccc(OCc2ccc(Cl)cn2)cc1=O +CN(CC=CC=Cc1ccc(-c2ccccc2)cc1)Cc1cccc2[nH]ccc12 +O=[N+]([O-])c1ccc(SC(=S)N2CCN(C(c3ccccc3)c3ccccc3)CC2)c([N+](=O)[O-])c1 +N#Cc1ccc(NC(=O)c2ccc3cccnc3c2O)cc1 +N#Cc1ccc2c(Cl)c(C(=O)Nc3ccccc3)sc2c1 +CCCn1ccc(-c2cc(-c3ncc(C)cn3)n3cc(NC(=O)NCC)nc3c2)cc1=O +CSc1nn2c(=O)cc(N3CCOCC3)nc2n1Cc1cccc(C(F)(F)F)c1C +CCCCC12CCC(=O)C(C(=O)OC)=C1c1ccc3[nH]ncc3c1C2 +Nc1nc(OCCc2c[nH]c3cc(Cl)ccc23)nc2c1ncn2C1OC(CO)C(O)C1O +CN(C)C1CCN(C(=O)c2cccc(Nc3nc4nc5c(cnn35)CCCCC(=O)Nc3cccc(c3)N4)c2)C1 +OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 +COc1ccc(OC)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cccnc2)c1 +O=C(Nc1cc2ccc(-c3cnccc3C(F)(F)F)cc2cn1)C1CC1 +Cc1ccc(-c2cncc(C(CC(=O)O)NC(=O)C3CCCN(C(=O)CCC4CCNCC4)C3)c2)cc1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)C1)c1ccc(-c2cccs2)cc1 +Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCC(C)C)CC(=O)N2 +O=S(=O)(c1ccc2ccccc2c1)c1n[nH]c2ccc(NC3CCNCC3)cc12 +CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CC(C4CCOCC4)C3)n(C)c2n1 +Cc1ccc2c(c1)N(C)C(=CC=Cc1oc3ccccc3[n+]1C)O2 +CC(C)COc1cn(-c2ccc(C(=O)O)cc2)cc1C#N +O=C(C1CCCN1S(=O)(=O)c1ccc2ccccc2c1)N1CCN(c2ccnc3cc(Cl)ccc23)CC1 +COc1ccc(CNC2COC(C(c3ccccc3)c3ccccc3)CC2O)c(F)c1 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+Cc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)NC4CCN(C5CC5)CC4)cc3Cl)nc1-2 +CC(C)Oc1cc(C2(Cc3cccc(OC(F)(F)F)c3)CN(CC(O)C(F)(F)F)c3ccccc32)ccn1 +C=CCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(-c3ccco3)ccc21 +O=Cc1ccn(-c2cc3c(cc2C(F)(F)F)nc(O)c2nc(C(=O)O)nn23)c1 +O=C(c1ccccc1N1Cn2c(ccc2-c2ccccc2)C1=O)N1CCCCC1 +CC(C)N1CCc2nc(C#Cc3ccccc3)ccc2C1=O +COc1ccc2c(c1)C1(CCN(C)CCO)CCCCC1C=C2 +CNC(C)C(=O)NC(C(=O)NC1CCCN(CCc2c[nH]c3ccccc23)C1)C(C)(C)C +CN(CCOc1cc(Cl)ccc1Cl)CCN1C(=O)CC2(CCCC2)CC1=O +CCc1ccc(-c2nc(C)oc2-c2ccc(S(C)(=O)=O)cc2)s1 +CC(=O)c1cccc(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)c1 +C=CCC(C(=O)NO)N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 +COc1cccc2c(=O)[nH]c(-c3ccc(C)cc3)nc12 +Cc1nc(NC(C)c2ccnc(Cl)c2)cc(-c2ccc3ncsc3c2)n1 +O=C(Cc1ccccc1O)NCCCNCCCCCCCCNCCCNC(=O)Cc1ccccc1O +CNC(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +c1ccc(C(c2ccccc2)N2CCN(c3ncnc4c3cnn4-c3ccccc3)CC2)cc1 +CC(C)N1CCC(Oc2ccc(C(=O)NC3CCN(C4CCC4)C3)c(F)c2)CC1 +O=C(O)c1ccc(CCCN2C(C=CC(O)Cc3cccc(OC(F)(F)F)c3)CCS2(=O)=O)s1 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+O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1cc(Cl)cn12 +CCOC1CCC(N2CC(NC(=O)CNc3n[nH]c4ccc(C(F)(F)F)cc34)C2)CC1 +O=C1COc2ccc(OCC3CCCN(CCOc4cccc5ncccc45)C3)cc2N1 +CCCNC(=O)Oc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +CN(CCO)Cc1ccn2c(-c3ccnc(N)n3)c(-c3ccc(F)cc3)nc2c1 +O=C1CCCN1c1ccc(S(=O)(=O)NNc2ccc(Br)cc2)cc1 +Cn1cc(NC(=O)c2ccc3nc4n(c3c2)CCCNC4=O)cn1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)cn3)c2)c2cnccc21 +CC(C)(CC(O)(Cc1cc2cc(N3CCOCC3)ncc2[nH]1)C(F)(F)F)c1ccccc1S(N)(=O)=O +Cc1nc(N2CCC(O)C2)ccc1-c1cc(C(F)(F)F)cc2[nH]ncc12 +COc1ccc(C(=Cc2cc(OC)c(OC)c(OC)c2)C(N)=O)cc1N +O=[N+]([O-])c1ccc(Cc2ccc3ccccc3c2O)cc1 +COc1cc(C(=O)N2CCC2c2nc(-c3cccc(F)c3OC)no2)c(-n2nccn2)cc1C +Cn1cc(-c2ccc(Cn3cc(C(=O)NC4CCOCC4(C)O)c4ncccc43)c(F)c2)cn1 +CC1CCC2C(C)C(OCc3ccc(C(=O)O)cc3)(C(F)(F)F)OC3OC4(C)CCC1C32OO4 +Cc1cc(C)[n+](CC(=O)Nc2nccc(Nc3ccc(S(N)(=O)=O)cc3)n2)c(C)c1 +CCn1ncc2c1CN(c1ncnn3c(C)nc(C4CCOC4)c13)CC2 +c1ccc2c(c1)c1cc[n+]2Cc2ccc(cc2)C[n+]2ccc(c3ccccc32)NCc2ccc(cc2)CN1 +CN(C)c1ccc(C(=O)C=Cc2ccc(I)cc2)cc1 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+O=[N+]([O-])c1ccc(NCCNc2ncc(-n3cnnn3)c(-c3ccc(Cl)cc3Cl)n2)nc1 +COC(c1ccc(Cl)cc1)(c1ccc2c(c1)c(-c1ccccc1C(F)(F)F)cc(=O)n2C)c1cncn1C +CC12CCCC(C=CC(=O)NS(=O)(=O)c3ccc(F)cc3)=C1N(Cc1ccc(Cl)cc1Cl)C(=O)C2 +CCCCCCCCC=CCCCCCCC(=O)c1ncc(-c2ccccn2)o1 +O=C(c1cc(Cc2c[nH]c(=O)c3cc(Cl)c(Cl)n23)ccc1F)N1CCC(N2CCC2)CC1 +O=C(Cc1ccccc1)Nc1nc(-c2cccs2)nc2cn(-c3ccccc3)nc12 +COc1cccc(-c2ccc(N3CC4CN(C)CC4C3)cn2)c1 +C=CCNc1nc(N2CCC(NCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)nc2c1ncn2CC=C +Cc1ccccc1-c1ccc2nc(N)c(CCC(=O)NCC3CCCCC3)cc2c1 +CC#CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CCCCC1CCN(C(=O)OC(C)C)CC1)c(=O)n2C +COc1cccc(-c2csc(C3(CNC(=O)c4ccc(Cn5nc(C)cc5C)cc4)CCOCC3)n2)c1 +CC(C)(C)COc1ccc(-c2cc(O)nc(N)n2)cc1C#N +O=C1NC(c2cncc(C#CC3CC(F)(F)C3)c2)C(c2ccc(F)cc2F)O1 +Cc1cc(C)cc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Cl)cc2)c1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3cc(Cl)ccc3[nH]2)n1 +Cc1nc(Nc2c(Cl)cc(C(F)(F)F)cc2Cl)c(=O)n(C(C)C2CC2)n1 +CC(C)(C)N(CCC(N)=O)C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 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+O=[N+]([O-])OCCCN1CCN(Cc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2O)CC1 +O=C(NCc1cccc2ccccc12)c1cc(-c2ccncc2)nc2ccccc12 +CNC(=O)CC1OC(n2cnc3c(NCc4ccccc4)ncnc32)C(O)C1O +CC(C)(C)C1NC(=O)C(CN(O)C=O)CCCCCCCCCCNC1=O +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCCN3C)cc12 +COC(=O)C1CC(OC(=O)CSC#N)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +CCC(CO)Nc1nc(NCc2ccccc2)c2ncc(C(C)C)n2n1 +Cc1cnc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cn1 +CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1Br +COc1ccc(CN2CCC(CCCC(=O)c3ncco3)CC2)cc1 +CCCCn1c(=O)n(CC(=O)NC(C)(C)C)c(=O)c2c(C)cccc21 +CC(=O)Nc1nc(CCc2ccc(-c3c[nH]c(N)n3)cc2)cs1 +CCOC(COC1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1)c1ccccc1 +CC(C)COc1cccc(O)c1-c1cc(C2CCNCC2)c(C#N)c(N)n1 +O=c1[nH]c(C2CCN(C3CCOC3)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +CC(O)CN1c2cccc(-c3cccc(OC(F)(F)F)c3)c2CCC1c1cccc(OC(F)(F)F)c1 +COc1ccc(Cc2cc(C3CCN(C(=O)c4ccc5c(c4)OCO5)CC3)nc(Cl)n2)cc1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3ccccc3)c(Oc3ccccc3OC)s2)cc1 +CC(Nc1cccc(F)c1C#N)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +CCCC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c1ccccc1 +O=C1c2cccc3cc(O)cc(c23)C(=O)N1CC1CCN(CC(O)COc2cccc3[nH]c4ccccc4c23)CC1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)C1CCCCc2ncsc21 +COc1cc(-c2c(C(C)C)cccc2C(C)C)ccc1C(C)C#Cc1c(C)nc(N)nc1N +N#CC(Cc1ccc(-c2cccc(C(N)=O)c2)cc1F)NC(=O)C12CCC(CC1)CN2 +On1cc(C2CCNCC2)c(-c2cn(Cc3ccccc3)c(Cl)n2)n1 +CCC(c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CCC(CC)(c2ccccc2)OC1=O +Cc1nnc(C(N)CCC(=O)Nc2cc(Cl)cc(S(=O)(=O)O)c2O)o1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCC(n4cn[nH]c4=O)CC3)cc2F)cn1 +COc1ccc(-n2nnnc2C(F)(F)F)cc1CNC1CCN(C(=O)C2CN(C(C)=O)C2)CC1c1ccccc1 +CN1CC2CN(Cc3c2c2ccccc2n3Cc2ccc(C(=O)NO)cc2)C1=O +COc1ccccc1N1CCCN(CCCCNC(=O)c2ccc(CCF)cc2)CC1 +CNCC(NC(=O)c1ccc(-c2nc(C3CCC(O)CC3)cnc2N)cc1F)c1cc(F)cc(Br)c1 +Cc1cnc(-c2cccc(Cl)c2)nc1N(C)CCCOc1ccc2c(c1)CCC2CC(=O)O +CCC(c1nc2snc(C)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1N1CCC(O)CC1 +Cc1ccc(-c2cc(Cl)ccc2OCC2CCCC2)n1-c1cccc(C(=O)O)c1 +CC(CCCn1cnnn1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +O=C(Nc1nnc(SCc2ccc(F)cc2)s1)c1ccc(Cl)cc1 +CCc1n[nH]c(CC)c1Oc1cc(C#N)cc(C#N)c1 +COc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3ccc(OCCN4CCCCC4)cc3)CC2)cc1 +O=C(Nc1ccc(F)cc1)NC1C2CCN(CC2)C1Cc1cccnc1 +COc1c(Nc2ncc3c(n2)N(C2CCCC2)CC(F)(F)C(=O)N3C)ccc(C(=O)NC2CCN(C)CC2)c1F +CC(=O)NC1CC(COC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)NC1=O +O=S(=O)(c1ccccc1)c1cc(Nc2cc(-c3ccc(F)cc3)[nH]n2)nc(NC2CCC(O)CC2)c1 +COc1cc(-c2cnc[nH]2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc12 +O=c1c2cn[nH]c2c2ccc(-c3ccncc3NS(=O)(=O)c3cccc(Cl)c3)cc2n1CC(F)(F)F +COc1cccc(C(=O)NCCN2CCN(c3ccccc3Cl)CC2)c1 +CCC1(O)Cc2cc3n(c(=O)c2COC1=O)CC1=C(CN2CCC(C)CC2)C2C=C(C)C(Cl)=CC2N=C13 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CN1CCN(S(=O)(=O)c2ccccc2)CC1 +CCCN1CCC(N(C)CCc2ccc(OC)c(OC)c2)CC1 +CNc1ncnc(-c2cc(C)cnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)ccc2C)n1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc(-c2ncccc2C(F)(F)F)cc1F +N#CC1CC(F)CN1C(=O)C(N)Cc1ccccc1C(F)(F)F +c1cc(N2CCC(N3CCCC3)CC2)ccc1CCN1CCC1 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+O=C(CC1CCCCN1c1cc(-n2ccnc2)nc(-n2ccnc2)n1)NCc1ccc2c(c1)OCO2 +C#CCNC(=O)c1ccc(OC2CCN(CC(c3ccccc3)c3ccccc3)CC2)c(OC)c1 +Oc1ccc(C2=c3ccc4n3C3C(=CC=4)CCCCC23)cc1 +CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)S(=O)(=O)c3ccccc3)ccc21 +C=COC(=O)N(C)N=Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1 +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)c1ccccc1-c1ccccc1 +Cc1nc(-c2ccc3c(c2)c(C#N)cn3CCNS(C)(=O)=O)sc1C(=O)O +COC1CC(CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +CNCCOc1ccc(C(=C(CCCO)c2ccccc2)c2ccc(O)cc2)cc1 +N#CC1CSCN1C(=O)CN(N)C1CCN(CC(=O)Nc2ccc(Cl)cc2)CC1 +COc1ccccc1-c1cc(-c2ccccc2C#N)c(=O)n(-c2ccccc2)c1 +COc1ccc(Cl)cc1CC1CNC(=NOc2ccccn2)CN(C(=O)NC(C)c2ccc(C(=O)O)c(N)c2)C1=O +COc1cc(OCCCN(C)Cc2ccc(OC)c(OC)c2)ccc1NC(=O)c1cccc2c(O)c3cccc(F)c3nc12 +CCC1CN2CCc3cc(OC)c(OC)cc3C2CC1CC1NCCc2c1cc(OC)c(OC)c2Br +Cc1nc2cccc(-c3cc4c([nH]3)C(C)NC4=O)c2nc1NC(C)C +Cc1cc(C(=O)N2CC(C)NC(C)C2)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21 +COCc1nc(NC(=O)NC(c2ccccc2)C2CCCO2)cc2[nH]nc(OC)c12 +CC(C)Oc1cccnc1N(C)C1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +Cn1ncc(NC(=O)c2nc(-c3ccccc3F)ccc2N)c1N1CCC(N)CC(F)(F)C1 +c1cnc(Oc2ccc(Nc3nc4ccccc4[nH]3)cc2)c(C2CCOCC2)c1 +COc1ccc(OC)c(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(N4CCN(C)CC4)cc3)n2)c1 +CCCCCCCCCC(=O)Nc1ccc(CP(=O)(O)O)cc1 +CCc1cc(=NCCC2CCN(Cc3ccccc3)CC2)[nH]nc1-c1ccccc1 +CCCCc1nnc(SCC(=O)c2ccccc2)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +CCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C +CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCC2CCNCC2)cc1 +O=C(c1ccc(-c2ccccc2)s1)c1c(F)ccc(O)c1F +Cc1ccc(CN2CCN(Cc3cccc4c3OCO4)CC2CCO)cc1 +CC1CCC(Cn2c(N3CCOCC3c3ccccc3)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1 +O=C(C=Cc1cccc([N+](=O)[O-])c1)NCCCCNc1c2ccccc2nc2ccccc12 +O=C1CSCN1CCCCN1CCN(c2ccc3ccccc3n2)CC1 +COC(=O)C(C)(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)OC +Cc1cccc(CC(O)C=CC2CCC(=O)N2CCSc2ccc(C(=O)O)s2)c1 +C[Si](C)(C=CCN1CC(O)C(O)C(O)C1CO)c1ccccc1 +CC(NC(=O)C=Cc1ccccc1F)c1ccc2c(c1)N(C)CCO2 +CCCCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(c1ccccc1Oc1ccccc1)N(C1CCC1)C1CCNC1 +Nc1cc(C2CCCNC2)nc2c(-c3cncnc3)cnn12 +COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 +COc1cccc(CNC(=O)C2(Cc3ccccc3)OC(=O)N(C(C)c3ccccc3)C2=O)c1 +O=C1COCC2=C1C(c1ccc(F)c(Br)c1)C1=C(COC1=O)N2 +CN(C)Cc1ccc(NC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)cc1 +CCCCCCN1CCN(c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)C1=O +Cc1cc(NC(=O)C2C(C)(C)C2(C)C)ccc1N1CCC(N2CCCC2C)C1 +O=C(O)C(O)=Cc1cc(OCc2ccc(F)cc2)ccn1 +[H]C([H])(CCCC)C([H])([H])C(C)(O)C1CCC2C3CC(O)C4CC(O)CCC4(C)C3CCC21C +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5ccccc5)co4)cc3)cc2)C(=O)NC(=O)NC1=O +CN1CCC=C(c2nsnc2OCCCCNCCCCCCCCNc2c3c(nc4ccccc24)CCCC3)C1 +CC(C)C12OC1C1OC13C1(C)CCC4=C(COC4=O)C1CC1OC13C2(O)CNc1ccc2c(c1)CC(=O)O2 +CN(CCCNC(=O)c1cccc2nc3cccc(Cl)c3nc12)CCCNC(=O)c1cccc2nc3cccc(Cl)c3nc12 +N#Cc1ccc2c(c1)C1CN(CCCCNC(=O)c3ccc(-c4ccccc4)cc3)CC1CO2 +CCCC(=O)Nc1nc(-c2ccccc2)cc(-c2ccc3c(c2)OCO3)n1 +Cc1cc(S(=O)(=O)NCc2ccncc2)cnc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +Cc1ccc(OCC(=O)Nc2cccc(CCc3n[nH]c(=O)c4c3CCCC4)c2)cc1 +O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1ccc(F)c(F)c1 +CN(C(=O)C1(c2ccccc2)CCCC1)c1ccccc1Cl +CN(C)CCOc1ccc(-c2nc(-c3ccncc3)c(-c3ccc4c(c3)CCC4=NO)[nH]2)cc1 +COc1cc(C2=NCCN2)ccc1-c1cn(-c2ccc(C3=NCCN3)cc2)nn1 +O=C(O)c1ccc(CCC2C(=O)CCC2C=CC(O)Cc2cccc(Br)c2)cc1 +CCOc1cccc(-c2ccc(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)c(OC)c2)c1 +O=C(O)c1cccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)c1 +CCc1cc(C(SCC(N)C(=O)O)(c2ccccc2)c2ccccc2)ccc1C +O=C(N1CCc2ncc(C(F)(F)F)cc2C1)C12CCOC1CC(N1CCC(c3ccccc3)CC1)C2 +O=C(NN=Cc1ccc(O)cc1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC1CCOC1 +O=c1[nH]nc(CN2CCN(c3nc4cc(F)ccc4n4cccc34)CC2)o1 +CC(C)c1onc(COc2c(Cl)cc(F)cc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +CCc1nc(Oc2cc(C)ccn2)c(CC)nc1NC1c2ccccc2CC1OC1CC1 +Cc1cnc2c(C(F)(F)F)cccc2c1-c1cccc(CNc2cccc3c(CC(=O)O)cccc23)c1 +Cc1c(Cc2ccccc2)nnc(N2CCN(c3cnc(C(=O)N4CCOCC4)cn3)C(C)C2)c1C +CCCCc1nc(Cl)c(CO)n1Cc1ccc(C(=O)c2ccccc2C(=O)O)cc1 +O=C(O)C(CCC(=O)N1CCC(CCCC2CCNCC2)CC1)NS(=O)(=O)c1ccccc1 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+COc1cc(Sc2c(-c3ccccc3)[nH]c3cccc(Cl)c23)cc(OC)c1OC +Cc1cc(C)cc(S(=O)(=O)c2c(C(N)=O)[nH]c3ccc(Br)cc23)c1 +CC1CCCCN1CCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)NC(C)(C)C)nc2n1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCN(C(=O)NC#N)CC3)cc12 +CC(C)Nc1nc(-c2ccc(C(C)O)cc2)cc2ncn(C)c(=O)c12 +O=C(O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)C1=O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(CN5CCCC5)s4)nc23)N1 +FC(F)(F)c1ccc(Nc2nnc(-c3ccncc3CCc3ccncc3)o2)cc1 +CCc1c(Sc2ccccc2)n(OCCC2CCCCC2)c(=O)[nH]c1=O +COc1cc(C)c(CC(N)C(=O)NC(C)C(=O)NCCCc2ccccc2)c(C)c1 +COc1cccc(-n2nc(C)c3c(O)c4ccccc4nc32)c1 +CC(C)CC(N)P(=O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)O +Fc1ccc(F)c(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1 +O=S(=O)(Nc1ccc2nccc(N3CCNCC3)c2c1)c1cc(Cl)cc(Cl)c1 +Cc1ccc(C(=O)N2C3CCC2C(Nc2cnc(C(F)(F)F)cn2)C3)c(-n2ccnn2)n1 +CCC(CO)Nc1cc(-c2[nH]c(SC)nc2-c2ccc(F)cc2)ccn1 +O=C(Nc1cc(Cl)ccc1N1CCC(CO)CC1)c1cnn2cc(O)cnc12 +Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCC(=O)c1ccc(F)cc1)CC(=O)N2 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+COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4cccc(C)c4)c3c2=O)CC1 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC(CO)CO +CNC(=O)c1nn(C)cc1NC(=O)c1nc(CC(C)C)ncc1Nc1cncnc1 +COc1ccc(C(=O)N2CCN(c3cc4c(cc3F)c(=O)c(C(=O)O)cn4C3CC3)CC2)c(O)c1 +O=C(c1ccc(O)cc1)N1CCCC2c3ccccc3CC21 +CCC(NC(=O)c1ccc2c(ccn2Cc2ccc(Cl)nc2)c1)c1ccccc1 +COC(=O)C=CC=CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 +O=C1NCCc2ccc3c(c21)CC(N(CCCc1c[nH]c2ccc(F)cc12)C(=O)c1ccccc1)CO3 +Nc1cnc(-c2ccc3c(c2)CN2CCC3(c3ccc(Cl)c(Cl)c3)CC2)cn1 +CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl +CSc1cncc(N2C(=O)CN(c3cccc(C(F)(F)F)c3)CC2C(=O)NC2CCCC2)c1 +CC1CN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CC4CC3CO4)n2)CC1F +COc1ccc(C2=C(c3cccs3)C(=Cc3ccc(C=CC(=O)O)o3)NC2=O)cc1OC +CN1C(=O)c2c(Cc3ccccc3)nn(C)c2N2C1=NC1CCCC12 +Cc1[nH]c(C(=O)NC2CCN(c3ncc(C(=O)O)s3)CC23OCCCO3)c(Cl)c1Cl +OCC1CCCN1CCOc1ccc(C2Oc3ccc(O)cc3SC2c2ccc(O)cc2)cc1 +Cc1nnc(-c2ccc(-c3ccccc3)cc2)n1-c1cccc(OCCCCCCN2CCN(C)CC2)c1 +c1ccc(Cn2nnnc2C(c2ccc(Oc3ncccn3)cc2)N2CCCN(C3CCC3)CC2)cc1 +CC(Nc1c(-c2c(F)cc(NCCCN(C)C)cc2F)c(Cl)nc2ncnn12)C(F)(F)F +CCC(CC)Oc1ccc2n(n1)c(N)n[n+]2CC(=O)c1cc(Cl)cc(OC)c1 +Cc1ncc([N+](=O)[O-])n1CCNS(=O)(=O)ON +Cc1ncc(F)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COc1ccc(C)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 +CCCN1CCC=C(c2ccc(Nc3nc(Nc4cc(F)ccc4C(N)=O)c4cc[nH]c4n3)c(OC)c2)C1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CC(C)(c3ccccc3)CC2C1 +CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(=O)O)c2ccccc2)c(Cl)c1 +CCC1C(C)C(Nc2ccccc2)c2ccccc2N1C(=O)Nc1ccccc1 +COc1cccc(CC2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)c1 +COc1ccc(CN2CCN(CCCCCCCCN3C(=O)c4ccccc4C3=O)CC2)cc1 +CN(C)c1ccc(C=Cc2cc(-c3ccccc3)o[n+]2C)cc1 +O=S(=O)(Cc1ccccc1)N1CCC(NC(c2cnccn2)c2ccc(F)cc2F)CC1 +CCOP(=O)(O)CCCCn1c(-c2cccnc2)c(C)c2ccccc21 +COc1ccc(CNC(=O)c2ccc(CC(NC(=O)C3CCC(=O)N3Cc3ccccc3)C(=O)O)cc2)cc1 +CN(CCCc1ccccc1)C(=O)c1cc2ccccc2[nH]1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3cccc(F)c3)o2)C(C)O)c(C)c1Cl +CC(C)(C)c1ccc(-n2nnnc2SCC(=O)Nc2ccc(S(C)(=O)=O)cc2Cl)c(Cl)c1 +CCCn1c(=O)c2nc(C3CCC(C(=O)N(C)CCN(C)C)CC3)[nH]c2n(CCC)c1=O +O=C(O)c1cnc(NC2CC2)n2nc(-c3ccco3)nc12 +CCOC(=O)c1cccc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 +COc1cccc(C(=O)Nc2cc(-c3ccccc3)nn2-c2ccccc2)c1 +O=C(N1CCC(c2c[nH]c3ncccc23)C1)C1(c2ccc(Cl)cc2)CC1 +CNCc1ccccc1-c1ccc(N2CCc3c(C(N)=O)nn(-c4ccc(OC)cc4)c3C2=O)cc1 +Cc1nc(C)c(CNc2cc(C(=O)NCCc3ccccn3)nc3ccnn23)s1 +CC(O)CNC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1 +COc1ccccc1Cc1c(C(=O)c2ccc(C)cc2C)oc2cc(O)ccc12 +C=CC(=O)Nc1cccc(CNc2nc(Nc3ccc(N4CCNCC4)cc3OC)ncc2C2CC2)c1 +CCC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)nc2c1Nc1ccc(N2CCCC(N)C2)nc1 +c1cc2ccc(-c3nc(N4CCOCC4)c4nc[nH]c4n3)cc2[nH]1 +OCC1CCN(CC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)C1 +COc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)ccc1-c1cccnc1Cl +CN(C)C(=O)Oc1ccc(-c2cn3c(NC(=O)c4ccccc4)cccc3[n+]2C)cc1 +CC(C)n1nc(-c2ccc3c(ccn3C)c2)c2c(N)ncnc21 +CC(C)c1nn(-c2ccc(C(N)=O)c(NCC(F)(F)F)c2)c2nccc(-n3cnc(-c4cnn(C)c4)c3)c12 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(CNCCC(=O)O)cc2C)ncn1 +N#Cc1cc2c(Oc3ccc(F)cc3OCCn3ccc(=O)[nH]c3=O)cccn2c1 +CCCS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1 +c1ccc(C(CCc2nc(CCNCCc3ccccn3)c[nH]2)c2ccccc2)cc1 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(Cl)ccc23)C1(C)C +N=C(N)c1cccc(CN2CCC(NS(=O)(=O)c3ccc4cccnc4c3)C2=O)c1 +O=[N+]([O-])C=C(NCCCn1ccnc1)Nc1ccc2c(c1)OCCO2 +Nc1cc(-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3cccnn3)cc2Cl)ccn1 +Cc1c(C(=O)CSc2ccc(C(=O)Nc3ccc(F)cc3)cn2)sc2ccc(Cl)cc12 +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(C(F)(F)F)c(Nc2ccc(N3CCN(C)CC3)cc2OC)n1 +C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(C(C)C)cc1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccnc(C#N)c1 +Cc1cc(-c2ccccc2)cc(C)[n+]1CC(=O)Nc1ccc2nc(S(N)(=O)=O)sc2c1 +O=C1CN(Cc2cncn2Cc2ccc(-c3cc(Cl)cc(Cl)c3)cc2)CCN1c1cccc(Cl)c1 +CCCN(c1ccccc1Br)S(=O)(=O)c1ccc(O)c(C(F)(F)F)c1 +N=C(N)c1cccc(C2=NOC(Cn3cnnn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3Cl)C2)c1 +CC(C)n1nc(-c2cc3cc(C=O)ccc3s2)c2c(N)ncnc21 +FC(c1ccc(Cl)cc1)(c1cccnc1)c1ccccc1Cl +CN1CCC(NC(=O)c2cnc(NCc3cc(Cl)ccc3Cl)nc2NC2CCCC2)CC1 +O=C1COc2c(cccc2C(O)CNCCN(C(=O)CCNCCc2ccc(Cl)c(Cl)c2)C2CCCCC2)N1 +COC(=O)C(Cc1cccc(C(=N)N)c1)C(C=Cc1ccccc1)NC(=O)c1ccccc1 +Cc1[nH]c(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)NC2CCC(C)CC2)nc1C(=O)O +NS(=O)(=O)c1cc(C(=O)c2ccc(CNCc3ccccc3)cc2)cs1 +Nc1ncnc2c1sc1cc(-c3ccc(CO)cc3)ccc12 +CCC(C)(Cc1ccc(OCCCOc2ccc(C(F)(F)F)cc2Cl)cc1)C(=O)O +OC(CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccc(Br)cc1 +CC(C)S(=O)(=O)NCC1CCC(NC(=O)Cn2ccc3ccccc32)CC1 +CN1C(=N)NC(C)(c2sc(-c3cncc(-c4cnco4)c3)cc2F)CS1(=O)=O +COC(=N)NS(=O)(=O)c1ccc(NC(=O)C(Cc2ccccc2)NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 +CC1(CNCC2CCN(c3ncccn3)CC2)COc2ccccc2O1 +CC#CCC(C)C(O)C=CC1C(O)CC(F)C1CC(=O)CCCCC(=O)O +Cc1cccc(N2Cc3cccc(C(N)=O)c3C2=O)c1 +COc1cc(C=NNC(=O)CC2(C)OCCCO2)ccc1OCc1ccccc1 +COCCNCCc1ccc(-c2cc3ncn(C)c(=O)c3c(NC(C)C)n2)cc1 +O=C(C=CC(=O)NCCCN1CCOCC1)Cc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +O=C(NCCc1cccs1)NCc1cccc(-c2cccc(-c3cc4c[nH]ccc-4n3)c2O)c1 +CC(C)Cc1ccc2c(NCCCNCc3ccco3)ccnc2c1 +CS(=O)(=O)c1cccc(-c2ccc3ncc(-c4cncc(S(C)(=O)=O)c4)n3n2)c1 +Cc1ccccc1NC1=CC(=NS(=O)(=O)c2cccs2)c2ccccc2C1=O +Cc1c(Cl)cccc1CCCCOc1ccc(C#Cc2cccc3c(CCC(=O)O)c(C)n(CCC(=O)O)c23)cc1 +Cc1cc(CN2CCC(O)CC2)ccc1C(=O)Cn1ccc(OCc2ccccc2)cc1=O +COC(=O)c1c(Cc2ccc(C(=O)NC3C4CC5CC3CC(N)(C5)C4)cc2)c(=O)c2cccnc2n1-c1ccccc1 +Cc1cc(Nc2nc(NCc3cc(-c4ccccc4)no3)ncc2Br)[nH]n1 +CN(C)CCNc1n[n+]([O-])c2ccccc2[n+]1[O-] +CC(C)CC(CP(=O)(O)C(N)CC(C)C)C(=O)O +Cn1nc(NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)cc1-c1ccccn1 +N#Cc1cc(-c2nc(N)[nH]c(=O)c2Cl)ccc1OCCCCO +OC1C[N+]2(Cc3ccc(CCc4ccc(C[N+]56CCC(CC5)C(O)C6)cc4)cc3)CCC1CC2 +Cc1cnc(C(CO)Cc2cccc3ccccc23)cc1OC1CCCCC1 +Fc1ccc(Cn2c(NC3CCNCC3)nc3ccccc32)cc1 +OC1(c2ccc3ccccc3c2)c2ccc3ccccc3c2C2=NCCN21 +Cc1c[n+]([O-])cc(C)c1C(=O)N1CCC(C)(N2CCN(C(C)c3ccc(C(F)(F)F)cc3)C(C)C2)CC1 +CCOc1ccc(S(=O)(=O)N2CCC(n3cc(C)c4cc(Cl)ccc43)CC2)cc1 +Cc1c(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)nnn1-c1ccccc1F +NS(=O)(=O)c1ccc(-n2nc(-c3ccc(C4CCCCC4)cc3)ccc2=O)cc1 +CN1CCCC1CCN1CCCc2cc(NC(=N)c3cccs3)ccc21 +COC12CCC3(CC1CNC(=O)CCc1nnn[nH]1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +OCC1OC(Oc2ccc(-c3ccc(C(F)(F)F)cc3)cc2Cl)C(O)C(O)C1O +O=C(Nc1cccnc1)N1CCC2(CCCN2Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +Nc1nc(N)c2c(-c3ccc(F)cc3)c(-c3ccc(F)cc3)[nH]c2n1 +Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(=O)C(C)C)C2=O)c1 +Cc1c[n+](Cc2ccccc2)ccc1C=Cc1ccccc1 +CN(C)Cc1ncccc1-c1ccc(-c2ccc3c(C(N)=O)nn(-c4ccc5onc(N)c5c4)c3c2F)c(F)c1 +Cc1nc(N)nc(-n2c(Nc3ccc4cc[nH]c4c3)nc3ccccc32)n1 +COc1ccc(C(=O)c2cccc(C=c3[nH]c(=O)c(=Cc4nc[nH]c4C(C)(C)C)[nH]c3=O)c2)cc1 +CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(-c2ccc(OCc3ccc(Cl)cc3)cc2)cc1 +COc1ccc(S(=O)(=O)N2CCN(C(=O)NCc3ccccc3)CC2C(=O)NO)cc1 +COc1ccc(N2CC(CN3CCC(O)(c4ccc(Cl)cc4)CC3)OC2=O)cc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCCCCC1=O +CC1C(c2ccccc2)CC(NC(=O)c2cnc3c(c2)CC2(C3)C(=O)Nc3ncncc32)C(=O)N1CC(F)(F)F +CCCNc1ncc(-c2cc(-c3ccc(F)cc3)nc(-c3ccccn3)n2)s1 +CC(Nc1cncc(Cl)n1)c1cccc(NC(=O)c2cncc(Br)c2)c1 +COc1ccc(-c2c(COC(C)=O)c(COC(C)=O)cc3ccc4c(c23)OCO4)cc1OC(C)=O +CC1OC(n2cc(-c3ccccc3)c3c(NCC(=O)NC4CCC4)ncnc32)C(O)C1O +CC1CCC(Oc2nccc3ccccc23)CN1C(=O)c1ccccc1-n1nccn1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=NCCN(C)C +Cn1c(-c2ccccc2)c(C2CCCCC2)c2ccc(C(=O)O)nc21 +CCCCCCN1C(=O)N(CCCC)C(=O)C1=Cc1cnc(CCCC)n1Cc1ccc(C(=O)OC)cc1 +Nc1nc(O)c2ncn(Cc3ccccc3CCP(=O)(O)O)c2n1 +O=C(c1ccc(F)cc1-n1nccn1)N1CCC2CN(c3nc4cc(Cl)ccc4o3)C2C1 +Cc1cc(S(=O)(=O)NCc2cccnc2)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)Nc1ccccc1 +CC1=C2CCc3cc(C(=O)Oc4ccccc4C(F)(F)F)ccc3N2CCC1=O +COC(=O)c1ccc(-c2c(C)[nH]c3cc(OC)c(Cl)cc3c2=O)cc1 +O=P(O)(O)C(CCCc1cccc(Oc2ccc(Cl)cc2)c1)S(=O)(=O)O +O=C(NCCCCN1CCN(c2ccccc2)CC1)c1ccc(Br)cc1 +Cn1cnc(S(=O)(=O)Nc2cccc(C(c3c(O)c4c(oc3=O)CCCCCC4)C3CC3)c2)c1 +O=C(Nc1cc2c(cc1F)C(O)C(F)(F)CC2)c1cc2cc(Cl)ccc2[nH]1 +COc1ccccc1CCNC(=O)c1cc(-c2ccncc2)nc2ccc(Br)cc12 +NS(=O)(=O)NCCCCC(NC(=O)OCc1ccccc1)C(=O)Nc1nc(-c2ccccc2)cs1 +Clc1ccc2c(NCCCNc3ccnc(N4CCCCC4)n3)ccnc2c1 +Cc1ccc(N2C(=O)c3cccc4c(N)ccc(c34)C2=O)c2cccnc12 +O=C(Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)C1OC1CN1CCCCC1 +COc1cccc(C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc2ccccc2)C(N)=O)c1 +CC(C)(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4ccccc4Cl)nc23)cc1 +CC(C)c1csc2nc(N3CCC(COCCN4CCCC4)CC3)ncc12 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccccc2CN2CCN(C)CC2)cc1 +O=C1c2[nH]nc(NS(=O)(=O)c3cccc4ccccc34)c2CCN1C1CCNCC1 +Nc1ccccc1NC(=O)c1ccc(CNC2=NC(c3ccc(O)cc3)CO2)cc1 +NC(CCc1cc(F)cc(F)c1)(C(=O)O)C1CC1C(=O)O +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1Cc1nnn[nH]1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NCCN(C)C)n1)C(C)(C)CN2 +CNc1nc(-c2ccccc2)[n+](-c2ccc(C)cc2)s1 +Cc1c(C(=O)NC2(c3noc(C(F)(F)F)n3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +COc1ccc(C)c(N2CCN(Cc3ccc(F)cc3Cl)C(=O)C2=O)c1 +CC(C)(C)c1ccc(Oc2cccc(CCCC(P(=O)(O)O)S(=O)(=O)O)c2)cc1 +Cc1nc2cnc3ccc(C#CCNC(=O)c4cccn(C(CO)c5cccc(F)c5)c4=O)cc3c2n1C(C)C +O=S(=O)(Nc1nccnc1-c1ccc(COc2ccc(Cl)nc2)cc1)c1ccccc1C(F)(F)F +CC(C)(C)OC(=O)c1ncn2c1CN(C(=O)OC(C)(C)C)c1ccccc1-2 +CCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 +CCOC(O)=C1C(COCCNc2n[s+]([O-])nc2N)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +Cc1ccc(S(=O)(=O)N(CC(=O)Nc2ccc(C#N)cc2)c2ccc(F)cc2)cc1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(C#N)cc3)nc2n1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccc(CN2CCCCC2)cc1Cl +COc1ccc2cc(-c3c(-c4ccncc4)nc(-c4ccc(S(C)(=O)=O)cc4C)n3C)ccc2c1 +COCC(=O)NC1CCC(C(=O)N(C)c2ccc(-c3nc4ccccc4o3)cc2)C1 +COc1cc(-c2ccc3ncc(C(C)=O)c(NC4CCC(CN(C)C)CC4)c3c2)cc(Cl)c1O +Cc1cccc(-c2noc(C3CCCN3C(=O)c3ccc(C)s3)n2)c1 +CN(C)c1ccc(C=C2COc3ccc(Br)cc3C2=O)cc1Br +CC(C)OCCOc1nc(Oc2cc(F)c3c(c2)COB3O)c(Cl)cc1C#N +CC(=O)c1cn(C)c2ccc(Nc3nccc(-n4cc(CN5CC(O)C5)c(C)n4)n3)cc12 +O=C(Nc1cccc2c1OC(c1nnn[nH]1)CC2=O)c1ccc(OCc2ccc3ccccc3n2)cc1 +Cn1cc2c(nc(NC(=O)Cc3cccs3)n3nc(-c4ccco4)nc23)n1 +Cc1cc(S(=O)(=O)c2cncnc2)cc2c3c(n(C)c12)CC1CCC3N1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5C(N)C5C4)cn3)nc2n1C1CCCC1 +O=C(Nc1ccc(N2CCN(C(=O)C3CCOC3)CC2)cc1)N1Cc2ccccc2C1 +CC(C)N(Cc1cn2c(N3CCN(C)CC3)cccc2n1)C1CCCc2cccnc21 +CCCNc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1Cl +CN(CCc1ccccc1)C(=O)Cc1cc(C=CC(=O)O)cc2c(-c3ccccc3)cccc12 +CCN1CCN(c2ccc(Nc3ncc(C)c(Nc4ccc5[nH]ncc5c4)n3)cc2)CC1 +O=C(c1cc(Cl)cc(Cl)c1)N1CCC(NCc2ccnc3ccccc23)CC1Cc1ccccc1 +Cc1cc(C)nc(NC(=S)N2CCN(c3ccc(C(F)(F)F)cc3Cl)CC2)c1 +CCOc1ccc(-c2cc(C(=O)O)c3cc(F)ccc3n2)cc1 +Cc1cnc(COc2ccc3nc(CC(C)(C)C(=O)O)n(Cc4ccc(OC(F)(F)F)cc4F)c3c2)c(F)c1 +O=C(Cn1c(-c2ncco2)cc2cc(F)ccc21)NCc1nc2ccccc2[nH]1 +COC(=O)Nc1ccc2c(c1)NC(=O)C(C)CCCC(N1CCC(c3cc(Cl)ccc3OC)=CC1=O)c1cc-2ccn1 +CC1C(c2ccccc2)C1(NS(=O)(=O)N1CCn2c(cc3cc(Cl)ccc32)C1)C(=O)O +Cc1ccc(-c2nn(CCN3CCN(c4ccccc4OC(C)C)CC3)c(=O)c3ccccc23)cc1 +CCCCN(CCCC)C(=O)c1nn(-c2ccccc2C(=O)N2Cc3ccccc3CC2CN)c(C)c1Cl +CC1CN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2F)CC(C)C1(O)c1cccc(C#N)c1 +CCCCCCC1C(=O)OC1C(=O)NCCCCC(NC(=O)C(C)NC(=O)OCc1ccccc1)C(=O)OCc1ccccc1 +CC(C)Nc1nc(-c2ccc(N3CCOCC3)nc2)cc2ncn(C)c(=O)c12 +O=C(CCCCCCCn1cc(-c2cccnc2)nn1)NCC(c1ccccc1)c1ccccc1 +CCN(CC)C(=O)c1ccc(C(=C2CC3CCC(C2)N3CCCc2ccccc2)c2ccccc2)cc1 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+O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2CCC(c3ccccc3)C1Cc1[nH]ncc12 +CCN(CC)c1ccc(C=NNc2c3c(nc4ccccc24)CCCC3)cc1 +c1cncc(CNc2csnc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c1 +CCCc1nc(C(=O)OCC)c2c(C)nc3ccc(OC)nc3n12 +COCCN(CCOC)c1nn2c(-c3cccc(Cl)c3)nnc2c2ccccc12 +CC(C)c1onc(C[S+]([O-])c2c(Cl)cccc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +N#Cc1c(C2CCCNC2)cc(-c2c(O)cccc2OCC2CCC2)nc1N +Cc1cc(Nc2ccc(Cl)cc2)n2nc(C(F)(F)F)nc2n1 +O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC2CCCC(F)(F)C2)cc1F +CN(CCCc1ccc(CN)cc1)CCNS(=O)(=O)c1ccc2ccccc2c1 +COc1cc(NC(=O)Nc2nccs2)cc(-c2cccnc2)c1OC +CCN(CC)C(=O)c1cccc(Oc2cccc(-c3c(C)cnc4c(Cl)cccc34)c2)c1 +CCCCCCCCCCCCCCCCNC(=O)C1(C)CC(c2ccc(C)cc2)=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1 +O=C(Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1)Nc1cc(F)cc(N2CCOCC2)c1 +Cc1ccc(CC(C(=O)NCc2ccc(C(F)(F)F)nc2SC2CCCCC2)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1ccncc1C)Oc1ccc(F)cc1-3 +COCC(C)N1CCc2nc(C(=O)Nc3cc(C(=O)O)ccc3CNC(=O)c3ccc(Cl)s3)sc2C1 +CCC(CO)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 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+Cc1noc(C)c1-c1ccc2c(c1)C(c1ccccc1)(N1CCC(NC(=O)OC(C)(C)C)C1)C(=O)N2 +Cc1cc(CN2CC(N)C(C(=O)C3CCCC3C#N)C2)ccc1C#N +O=C1NCCN1CCN1CCCC(c2c(-c3ccccc3)[nH]c3ccccc23)C1 +O=C(OCOCCN1CCOCC1)C1(c2ccc(Cl)c(Cl)c2)CCCCC1 +O=C(O)CC1Nc2cc(C(=O)NCCC3CCNCC3)ccc2CN(CCc2ccccc2)C1=O +O=C(O)Cc1cnc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cccc(F)c1 +COC(=O)C1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCO2 +C#Cc1ccc2c(c1)-c1nc(C)ncc1Cc1c(C(=O)OCC)ncn1-2 +COc1ccccc1-c1ccc2c(c1)C(C(C)OCCCc1ccccc1)=CC(C)(C)N2 +Cc1cc(CC(OC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2ccccn2)cc2c(Cl)n[nH]c12 +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(C2CCC(O)CC2)sc2cc(O)ccc12 +c1cc(-c2cnc3c(-c4ccsc4)cnn3c2)ccn1 +CN1Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4CC5)c(F)c3)cc2C1 +COc1cc2nc(N(C)CCCCCCNC(=O)c3ccco3)nc(N)c2cc1OC +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(CCO)CC4)ncn3)c2c1 +CN1C2CCC1CC(OC(=O)c1cc(=O)n(C)c3ccccc13)C2 +CC1(C)CCc2[nH]c3cc(Cl)ccc3c(=O)c2C1 +COc1ccccc1N1CCN(CCCCN2C(=O)Cc3ccccc32)CC1 +Nc1nnc(-c2ccc3[nH]cc(-c4cccc(-n5cccn5)n4)c3c2)o1 +CN1CCCN(c2ncc3ncnc(Nc4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4Cl)c3n2)CC1 +CNC(=O)Cn1cc(-c2cnc(N)c3c(-c4cccc(C(=O)Nc5ccccc5)c4)csc23)cn1 +Cc1nc(N)ccc1CNC(=O)Cn1c(C)cnc(NCCc2ccccc2)c1=O +CC1CN(c2ccc(Cl)cc2)C(=O)c2cc(COc3ccc(F)cn3)nn21 +O=C(O)C(Cc1ccc(-n2c(-c3cccnc3)nc3cccnc32)cc1)NC1=C(Cl)C(=O)C12CCCCC2 +CS(=O)(=O)c1ccc(C2C(Oc3ccccc3)C(=O)N2c2ccc(F)cc2)cc1 +NC(=S)NN=C(C=Cc1ccccc1)c1ccc(Cl)cc1 +CCCCCCOc1ccc2ccn(CCC(CO)n3cnc(C(N)=O)c3)c2c1 +CC1(C)Cc2c(c(-c3ccco3)nc3sc4c(NCCCO)ncnc4c23)CO1 +O=C(Cc1ccsc1)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +Nc1ccc(Cn2ccnc2)c2c(=O)c3ccccc3oc12 +CC1C(Nc2ccc(Br)cn2)CCCN1C(=O)c1ccccc1-n1nccn1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cn(CCN2CCOCC2)c2ccccc12 +CC12CCC3C(CCC4CC5(CCC43C)CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC(=O)O5)C1CCC2=O +COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)cc(OC)c1OC +CC12CCC(O)CC1=CCC1C2CCC2(C)C1CCC2n1ccnc1 +CCCCC(C=NNC(=O)N1CCCc2ccccc21)NC(=O)OC(C)(C)C +O=C(C=Cc1cccc(S(=O)(=O)N2CCN(c3ncccn3)CC2)c1)NO +NC(=O)c1cccc2c1C(=O)N(C1CCN(Cc3cccc(Cl)c3)CC1)C2 +NCCCNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(NC(CO)c1ccc(F)c(Cl)c1)N1CCc2cnc(NCCO)nc2C1 +O=C(NCc1cccc(O)c1)C(=O)c1c[nH]c2ccc([N+](=O)[O-])cc12 +CCCOc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(OC(F)(F)F)c2)c1 +O=C(C1=C(Nc2cccc(Br)c2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1 +CC(C)(Cc1ccc(OC(F)(F)F)cc1)NCC(O)c1ccc(O)c2c1OCC(=O)N2 +CCOC(=O)c1cnn(CC(C)O)c1NC(=O)N1CCN(Cc2ccccc2)CC1 +CCNc1cc(N2CCNCC2)ccc1S(=O)(=O)c1ccccc1 +CCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 +O=C(NCc1ccccc1F)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CCN(CC)C(=O)c1cccc(Oc2ccc(-c3nc4cc(C(N)=O)ccc4[nH]3)cc2)c1 +Cc1oc(-c2ccccc2)nc1CCOc1cccc(CC2C(=O)N(c3ccc(Cl)cc3)C2C(=O)O)c1 +CCC(=O)N(Cc1cccc(OC)c1)c1cc(F)cc(-c2nnn[nH]2)c1 +CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)C(C)c2cc(F)ccc2Cl)ccc1Oc1ccc(F)cc1F +FC(F)(F)c1cccc(N2CCN(CCCCNc3ccc(-c4ccccc4)cn3)CC2)c1 +CN1CCN(c2ccc(Nc3nc4c(-c5cccc(CN(C)S(C)(=O)=O)c5)cccn4n3)cc2)CC1 +O=C(CCc1ccccc1)c1ccc(OCC(O)CN2CCCCC2)cc1 +O=C(NCc1cnc[nH]1)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +CC(=O)N(C)CCCn1c(-c2ccccc2)cc(C(=O)Nc2cccc(C(F)(F)F)c2)c1C +Cc1cc(Br)cc(C(=O)NO)c1N(C)S(=O)(=O)c1ccc(Oc2ccc(C(C)(C)C)cc2)cc1 +COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1C=CCCO +Cc1c(CC(=O)O)c2cc(Cl)ccc2n1C(=O)c1ccc(OCC2CN(C)c3ccccc3O2)cc1 +CC(=O)Nc1ccc(-c2ncnc3c2cc(C(=O)OCc2ccccc2)n3C)cc1 +COc1cc(-c2ccncc2NC(=O)c2nc(-c3c(F)cccc3F)ccc2N)cc(N)n1 +O=C(O)CCCCCc1ccn2cc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)nc2c1 +Cc1ccn2c(CC(=O)O)cc(-c3ccc(C(F)(F)F)cc3Cc3c(C)noc3C3CC3)c2n1 +O=C(Nc1ccc(F)c(-c2nc3ncc(Br)cc3o2)c1)c1ccco1 +Cc1n[nH]c(C)c1-c1nc(NCCN)c2c3c(sc2n1)CCCC3 +[C-]#[N+]c1cccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)c1C +Cc1cc(C#N)cc(C)c1Nc1nc(Nc2ccc(C#N)cc2)ncc1Br +O=C(c1cccc(F)c1-n1nccn1)N1CC2CN(c3ncc4cc(F)c(F)cc4n3)CC2C1 +NCC1CCC2C(c3ccccc3)Nc3ccc(C(F)(F)F)cc3C2O1 +Nc1cccc(C#Cc2cccc(C(=O)N3CCN(c4ccccn4)CC3)c2)c1 +CCCCc1nn2c(-c3ccccc3)cnc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cc(OC)cc(C(=O)N(CCCc2ccccc2)Cc2ccc(-c3ccccc3CCC(=O)O)cc2)c1 +CC(C)(C)c1ccc(C[N+](C)(C)CCCN2c3ccccc3Sc3ccc(Cl)cc32)cc1 +O=C(NN=Cc1ccccc1O)c1cc(-c2ccc(Cl)cc2)nn1Cc1ccc(Cl)nc1 +CC1SC(C)(C)C(=O)N1CCCCN1CCN(c2csc3cc(Cl)ccc23)CC1 +CNC(C)C(=O)NC(CCC(N)=O)C(=O)N1CCCC1C(=O)NC(c1ccccc1)c1ccccc1 +O=C(O)C1=Cc2cc(Cl)cc(-c3ccc(F)cc3)c2OC1C(F)(F)F +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1C(CC#N)COc1ccccn1 +CCCNc1ncc(-c2ccc(F)cc2)cc1C(=O)c1ccc(F)cc1 +Cc1cc(C(=O)O)c(-n2[nH]c3c(cnc4ccccc43)c2=O)s1 +CCN(CC)CCOC(=O)C(CC)(c1ccccc1)c1ccccc1 +COc1ccc2c(c1)CN(C(=O)N1CCCCC1)CCS2 +CC(c1ccc(-c2cnc(N)nc2)nc1)(c1noc(-c2cnn(CC#N)c2)n1)C1CC1 +Cc1c(C(O)CN2CCC3(CC2)CC(=O)N(c2ccc(C#N)cn2)C3)ccc2c1COC2=O +CCCCS(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 +NC(=O)C(CC(O)C(Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C1CCCCC1 +CCC(NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C(=O)N1CC(C#N)C1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(OC4CC4)cn3)C2)cc1 +CN1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1 +Cc1c2c(=O)n(-c3ccccc3)nc-2n(CC(=O)N(C)c2ccc(Cl)cc2)c2ccccc12 +CCCC=Cc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +COc1cc(N2CCCN(C(C)=O)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 +CN1CCN(CC(=O)N2CCc3cccc4c3C2CNC4=O)CC1 +CNC(C)C(=O)NC(C(=O)NC1CCCN(CCc2ccc([N+](=O)[O-])cc2)C1)C(C)(C)C +O=C(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 +CCn1cnc2c(-c3ccc(Cl)c(-c4ccc(S(=O)(=O)CC)cc4OC)c3)cnnc21 +CCc1cccc(C(=O)N(CC)c2ccnc(NC(C)c3ccccc3)n2)c1 +O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1CCCc2cc(-c3cccnc3)ccc21 +COc1ccc(C=CC(=O)NC(=O)c2ccccc2O)cc1 +CC(C)N1CCC(Oc2ccc(C(CCN(C)C)Oc3ccccc3)cc2)CC1 +CC1CN(c2ncc(F)cn2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +O=C(O)COc1cccc(CCn2ncc(-c3ccccc3)c2-c2ccccc2)c1 +CC(O)C1CCN(c2ccc(Cl)cc2NC(=O)c2cnn3cccnc23)CC1 +COc1cc(C=C2SC(=O)N(CC(=O)Nc3ccccc3F)C2=O)cc(Cl)c1O +CCCCc1nnc(SCc2ccccc2C#N)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +COc1ccc(CNc2nc(N3CCCCCC3)nc3c2ncn3C(C)C)cc1 +O=C1C2CCCCN2C(=O)N1CCN1CCN(c2cccc(Cl)c2)CC1 +CCC(=O)NC1CCC(C(=O)N(C)c2ccc(-c3nc4ccccc4n3C)cc2)C1 +COc1cc(NC(=O)Nc2ccccn2)cc(-c2cccnc2)c1OC +COc1cc(OCc2cccc(-c3cncnc3)c2)c2cc(-c3cn4nc(C(C)(F)F)sc4n3)oc2c1 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+Nc1c(N(CCC2=CCCCC2)C(=O)c2ccc([N+](=O)[O-])o2)c(=O)[nH]c(=O)n1Cc1ccccc1 +COc1ccc2c(c1)C(N1CCN(C(=O)C3CC3)CC1)CCC2 +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(Cc1ccccc1)N=Cc1cnn2ccc(C#N)cc12 +CCCS(=O)(=O)Nc1cc(F)cc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC)n2)c1Cl +COc1cc(C(=O)c2ccc(-c3csc(NC(=O)C(N)Cc4ccccc4)n3)cc2-n2cncn2)cc(OC)c1OC +O=C(CN1CCN(c2c(Cl)cnc3[nH]c(-c4ccc(CN5CCOCC5)cc4)nc23)CC1)Nc1nccs1 +Cc1c(S(=O)(=O)Nc2cccc(-c3nnn[nH]3)c2)sc2ccc(N)cc12 +Cc1cccc(-c2oc(C)nc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 +O=C(Nc1ccc(OCCN2CCOCC2)c(F)c1)c1cccc(-c2cccc(O)c2)c1 +CC(O)C(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5cnc6[nH]ncc6c5)nc4c32)CC1 +Cc1cc(-n2ccc(=O)cc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +COc1ncccc1C(C)c1c(CCN(C)C)sc2ccccc12 +C=C(C)C1CCC2(C(=O)NCCCCCO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CCc1nc(Nc2ccc(C#N)c(OCC=C(C)C)c2)nc(OCCOC)n1 +CN(C)Cc1cc(C=NN=C(N)CC(O)c2cc3ccccc3c3ccccc23)ccc1O +CC(C)(c1ccccc1)N1C2CCC1CC(Oc1cccc(C(N)=O)c1)C2 +COc1ccc(Cl)cc1N1CCN(CCN2C(=O)C3Nc4ccccc4C3N=C2C)CC1 +O=C(NCc1cccc(-c2cccc(CN3CCNCC3)c2)c1)c1cccc(C(F)(F)F)c1 +CC(C)C(O)CNc1cc(-n2ncc3cc(Cl)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)c(C)c3)c2cc1OC +Oc1c(Cl)cc(SSc2cc(Cl)c(O)c(Cl)c2Cl)c(Cl)c1Cl +COC(C)(C)c1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1 +CCc1cccc(N(C)C(=N)Nc2cc(C(F)(F)F)cc(CC)c2Cl)c1 +OC(c1ccccc1)(c1ccccc1)C1CCN(CCCOc2ccc(-c3ccccc3)cc2)CC1 +CON=C(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCN1CCN(C)CC1)c1ccc(Cl)c(Cl)c1 +CC1=C(C#N)C(C)(c2ccc(F)cc2)C(C(=O)OC(C)(C)C)=C(C)N1 +N=C(N)c1cc2cc(-c3cccc(OCc4ccc(F)c(Cl)c4)c3)ccc2s1 +COCCCc1cccc2cccc(CN(C(=O)C3CNCCC34OCc3cc(F)c(F)cc34)C3CC3)c12 +O=S(=O)(Nc1ccncn1)c1ccc2c(-c3ccc(C(F)(F)F)cc3C3=CCNCC3)cccc2c1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NCc1cnco1 +CCOC(c1ccccn1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +Fc1ccccc1-c1nc2cnn(Cc3cc(-c4ccc(Cl)cc4)no3)cc-2n1 +Cc1ccc2c(-c3nnc(SCCCN4CCc5nc6cc(C(F)(F)F)ccn6c5CC4)n3C)cccc2n1 +CS(=O)(=O)Nc1cccc(-c2ccc3nc(NC(=O)C4CCCCC4)nn3c2)c1 +Nc1nc(CNC2CCCN2Cc2ccnc(Cl)c2)nc2nc(-c3ccco3)nn12 +O=C(CN1CCC(NC(=O)c2ccc(Cl)s2)C1)Nc1ccc(-n2ccccc2=O)cc1F +CC(C)(C(=O)N1CCC(CC(=O)O)CC1)C(O)C=Cc1ccc(C(=N)N)cc1 +O=C(c1ccc(F)cc1)c1cc2n(c1)CCN(CCc1ccc(CN3CCCCC3)cc1)C2=O +C=C1C(=CC=C2CCCC3(C)C(C(C)CC[S+](=N)([O-])c4ccccc4)=CCC23)CC(O)CC1O +C=CCCCC(OC(=O)C1CCCCN1C(=O)C(=O)C1(O)OCCCC1C)C(C)=CC1CCC(O)C(OC)C1 +c1ccc2c(c1)OCC(c1nc3ccc(-c4ccncc4)cc3n1CCN1CCOCC1)O2 +CC(C)C(C(=O)NO)N(CCn1cc(CNS(=O)(=O)c2ccc(F)cc2)nn1)S(=O)(=O)c1ccc(OCCF)cc1 +CC(C)C(NC(=O)c1ccc2c(c1)OCCO2)C(=O)N(C)N(C#N)Cc1ccccc1 +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(N3CCc4ncsc4C3)c2cn1)c1ccc(F)cc1 +Cc1nc(N)nc(-n2c(Nc3cc[nH]n3)nc3cc(F)c(F)cc32)n1 +N#Cc1cccc(S(=O)(=O)Nc2ccc(Oc3ccccc3)cc2)c1 +O=C(CN1C2=NCCCN2c2ccccc21)c1ccc([N+](=O)[O-])cc1 +NCC1CCC(C(=O)NC(Cc2ccccc2)c2nc(-c3ccc(C(N)=O)cc3)c[nH]2)CC1 +CC(=Cc1ccc(C)cn1)C1CC2OC2(C)CCCC(C)C(O)C(C)C(=O)C(C)(C)C(O)CC(=O)O1 +NS(=O)(=O)c1ccc(CCNC(=O)c2ccccc2S)cc1 +Cc1cc(C#N)ccc1-c1ccnc(NCc2n[nH]c3nc(N)ccc23)c1 +O=c1[nH]c(C2CCN(C3CCCCC3)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +Clc1cccc(CN2CCCC(Nc3cccc4cnccc34)C2)c1 +CCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)nc1 +C=C(C)C1CCC2(COC(=O)n3ccnc3)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC(C)c1c(-c2nnc(CN3CCC(O)C3)o2)cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12 +CCCCc1nc(SC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1 +N#Cc1cc(Cl)cc(-c2cc(-n3cc(F)cn3)ncn2)c1 +O=C1C(c2c(O)[nH]c3ccc(Cl)cc23)=Nc2ccccc21 +CN(C(=O)c1ccccc1-c1nc2cc(-c3cnc(N)nc3)ccc2n1C(C)(C)C)c1ccccn1 +CC1CCC(NC(=O)c2cc3cccnc3n(CCCCF)c2=O)CC1 +CC(Nc1nc(N)nc(NCCc2ccc(F)cc2)n1)c1ccc(F)cc1 +CNC(=O)c1cccc2c1nc(Nc1ccccc1Cl)c1ccncc12 +CC(C)(c1cc(-c2cccc(-c3ccc[n+]([O-])c3)c2)c2ncccc2c1)S(C)(=O)=O +O=C(c1csc2ccccc12)N(CCc1ccc(Cl)cc1)C1CCC(O)CC1 +COc1cc(OCc2csc(C3CCC(F)(F)CC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +CCCCCNC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)CC1CCCCC1 +c1cc(C2CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)ccc1OCCN1CCCC1 +O=C1CCCc2cc3c(cc2N1)[nH]c1cc(C(F)(F)F)ccc13 +COc1ccc2c(nc(Nc3c(C)cccc3C)c3cncn32)c1OC +Cc1cccc(NC(=O)c2nc(C)n(-c3ccc(Cl)cc3)c2C)n1 +CCCCOc1ccccc1-c1ccc(N=Nc2cc(S(=O)(=O)O[Na])c3ccccc3c2N)cn1 +COC(=O)c1c(F)cccc1-c1ccc(CNc2ccc(C(=O)N3CCOCC3)cn2)c(F)c1 +CCCOc1ccc(-c2nc(-c3cccc4c3CCN4CC(N)(CO)CO)no2)cc1Cl +Cc1cccc2cc(Cn3nc(-c4cc(O)cc(F)c4)c4c(N)ncnc43)n(-c3ccccc3Cl)c(=O)c12 +CN1CCC(c2cc3c(-c4cccc(NCCN5CCOCC5)n4)ccnc3[nH]2)CC1 +NC1=NC(CCc2ccc(Nc3cccc4cccnc34)cc2)CO1 +O=C(O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2Oc2ccccc2OC(F)F)cn1 +COc1ccc(C(=O)CCC(=O)NNC(=O)Cn2c(C)nc3ccccc32)cc1 +CN1CCC23c4c5ccc(O)c4OC2C(OC2C=CC(O)C(C(=O)O)O2)C=CC3C1C5 +Cc1ccc2c(C)c(N(Cc3ccc(OC(F)(F)F)cc3)S(=O)(=O)c3ccc(C(=O)O)cc3)ncc2c1 +Cc1ccc(Cn2nc3c(C(F)(F)F)cccc3c2-c2ccc(F)cc2)c(C)c1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cc2ccccc2n1CCCCCO +Cc1cccc(NNC(=O)C(=O)c2c[nH]c3ccccc23)c1 +Cn1cc(C=CC(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(Cl)c3)cccc21 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2ccc(C(C)N(C)O)nc12 +Cc1nc(-c2nc(N)[nH]c2-c2ccc3nccnc3c2)ccc1F +CC1CCCCN1CCOc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccc(Cl)s1 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+CCc1nc(C=Cc2cccc(C(CCc3ccccc3C(C)(C)O)SCC3(CC(=O)O)CC3)c2)ccc1C(F)(F)F +CN(C)CCN(Cc1ccc(Cl)c(Cl)c1)C(=O)c1cc2scc(C(F)(F)F)c2n1-c1ccc(F)cc1 +Oc1ccc(CC2(O)COc3c(ccc(O)c3O)C2O)cc1O +O=C(Nc1ccc(Nc2nc(Nc3ccc(O)cc3)ncc2F)cc1)c1ccccc1F +COc1ccc(C(O)(c2ccc3nc(Cl)c(Oc4ccccc4)c(Cl)c3c2)c2cncn2C)cn1 +COc1cccc(NC(=O)N2CCOC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 +COC1c2ccccc2CC1Oc1cc(OC2CC(O)C(COS(N)(=O)=O)C2)ncn1 +COc1ccc2c(c1)-c1c(ccn1CC(C)N)C2(C)C +CCCCS(=O)(=O)NC(=O)C1=CC(OC(CC)CC)C(NC(C)=O)C(NC(=N)N)C1 +O=C1C(=O)N(CCc2ccc(Br)cc2)c2c(Br)cc(Br)cc21 +CCc1ccc(C(=CCC(N)C(=O)O)c2ccc(F)cc2F)cc1CC +CON=C(C)c1ncn2c1COc1c(CCN3CCN(c4cccc5nc(C)ccc45)CC3)cccc1-2 +COc1cc(C(=O)c2nc(-c3ccccc3)cn2C2CCCC2)cc(OC)c1OC +C#CCCOc1ccc(OC)cc1CCNC(=S)Nc1ccc(Br)cn1 +O=S(=O)(NCCO)c1ccc(-c2cnc(N3CCOCC3)c3nc(C=Cc4ccc5ccccc5n4)cn23)cc1 +CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3ccc(F)cc3F)CC2)CC1 +C=CCn1nc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)c1C(F)(F)F +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C12CN(c1ccc(-c3nnn[nH]3)cn1)CC2c1ccc(C#N)cc1 +CCOc1ccc(CC(NC(=O)c2ccccn2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)c(F)c2)cc1 +COCC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(C)C(=O)C4)ncn3)c2c1 +OCC1CC(n2nnc3c(NC4CC4c4ccccc4)nc(SCCC(F)(F)F)nc32)C(O)C1O +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)OC2COCCOCCOC2)cc1 +COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)C1c1cccc([N+](=O)[O-])c1 +CCCCc1nc2ccccc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN(C)c1ccc(C(=O)NCCCCNc2c3c(nc4ccccc24)CCCC3)cc1 +Clc1ccc(CSc2nnc(-c3ccccn3)n2Cc2cccnc2)cc1Cl +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(C4CCOCC4)C3)cc12 +O=C(Nc1cccnc1)C1CC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C(O5)C1=O +CS(=O)(CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC#N +N#CC1CCCN1C(=O)CNCCN1CCN(c2ccccc2)C1=O +Cn1c(=O)c2cnc(Nc3ccc(C(=O)O)cc3)nc2n1-c1ccccc1 +COc1ccc(-c2c(-c3ccncc3)nnn2CC(=O)Nc2ccc(-c3ccccc3)cn2)cc1 +CSCCNCC(C)(C)c1ccc(NC(=O)c2nc(C#N)c[nH]2)c(C2=CCC(C)(C)CC2)c1 +O=C(NCC1CCN(CCCS(=O)(=O)N2CCN(c3ccc(F)cc3)CC2)CC1)c1cccc2c1OCCO2 +Cn1cnc2cc(-c3ccc(N4CCC(O)C4)c(S(C)(=O)=O)c3)nc(N3CCC(CO)C3)c2c1=O +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(c2nnn[nH]2)CC1 +CN(C)Cc1ccccc1NC(=O)OCC(Oc1cccc2sc(C(=N)N)cc12)c1ccccc1 +O=c1[nH]c2ccccc2n1C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +NC(=O)c1sc(-c2cnc3ccccn23)cc1OCc1ccccc1C(F)(F)F +COc1ccc(C(=O)Nc2nc3ccc4nc(C)sc4c3s2)cc1 +CN(C)CCCN=C1CC(c2ccc(Cl)cc2Cl)CC2Nc3ccc(Cl)cc3C(=O)C12 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN(C(=O)c2ccccc2)c2ccc(C)cc2)cc1 +Cc1cn2nc(C3CCCCN3C(=O)c3cc(Cl)ccc3NS(C)(=O)=O)cc2nc1N1CCCC1 +CS(=O)(=O)N1CCCC(Nc2nc(N)ncc2-c2cnc3[nH]ccc3n2)C1 +CCSCC1(C(=O)Nc2ncc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 +CC1(C)CC2CC(C)(CN2C(=O)c2ccc(-c3ccc(-c4cccc5cccnc45)c(Cl)c3Cl)cc2Cl)C1 +COc1ccc(S(=O)(=O)N2CCc3cc(Br)cc(NC(=O)c4ccco4)c32)cc1 +CCOC(=O)C(O)c1cc(-c2ccc(S(C)(=O)=O)cc2)n(-c2ccc(OC)cc2)c1C +COc1cc(CN2C(=O)N(Cc3ccc(O)c(OC)c3)N(C(=O)CC3CCCC3)CC(O)C2Cc2ccccc2)ccc1O +O=C(NC1(c2ccc(Cl)cc2)CC1)c1nn(-c2ccccc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1 +COc1cc(N2CCN(C)CC2)ccc1Nc1cc(-c2c[nH]c3cnccc23)ncn1 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+O=C(CCCCCCC(=O)c1ncco1)Nc1cc2ccccc2[nH]1 +CN1CCc2c(sc(NC(=O)c3ccc([N+](=O)[O-])o3)c2C(N)=O)C1 +Nc1cc(-c2cccc(NCc3cccc(F)c3)n2)c(Cl)cn1 +O=C(O)C(Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1 +CC(C)(CNC(=O)C1(C#N)CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +COc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccc(S(C)(=O)=O)cc3)s2)cc1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)C1CCCNC1)C2 +CC1CC2=CC(=O)CCC2C2CCC3(C)C(CCC3(C)O)C12 +CCN(CC)c1ccc(C)c2nc(-c3c(OC)cc(COC)cc3OC)c(C)cc12 +O=C(Nc1nc2c(s1)CC(N1CCOCC1)CC2)c1cccc(C2CCCN2C(=O)c2cc(-c3ccncc3)[nH]n2)c1 +Cc1cccc(C#CC2(O)CC3CCC(C2)N3C(=O)C(C)(C)C)c1 +CC(CN1CCC2(C)CC1Cc1c(O)cccc12)OCc1ccccc1 +CNC(C)C(=O)Nc1cc(-c2nn(C)c3ncnc(N)c23)cc(NC(=O)c2ccccn2)n1 +Cc1cccc2c1S(=O)(=O)c1c(C)cccc1C2=O +Cc1nc(-c2ccc(OCC(C)C)c(C#N)c2)[se]c1C(=O)O +CCOC(=O)COCc1ccc(-c2ccc(CCN3CCCC3C)cc2)cc1 +Cc1cc(S(=O)(=O)NCc2cccs2)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)NCCN(C)C)c1=O +CC1(C)CCC2=C(C1=O)C(c1ccc(F)c(Br)c1)C1=C(CCS1(=O)=O)N2 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2c(ccn2S(=O)(=O)c2cccc(C(=O)O)c2)c1 +O=c1[nH]c2ccc(Cl)cc2n1S(=O)(=O)Cc1ccccc1 +COc1cc(Nc2nc3cccc(-c4ccc(NS(C)(=O)=O)cc4)c3o2)cc(OC)c1OC +CC(C)NC(=O)c1sc2ncnc(N3C4CCC3CC(N3CCCC3)C4)c2c1-c1ccccc1 +NCC(NC(=O)c1cc(-c2ccnc3[nH]ccc23)cs1)c1ccccc1 +CN(C)C12CC(OC(=O)CCN3CCCC3)C(C(c3ccccc3)C1)C(c1ccccc1)C2 +Cc1nnsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C)cc1 +CN(c1ncc(Br)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +O=S(=O)(c1ccccc1)c1cnc2cc(-c3ccc(Cl)cc3)nn2c1-c1ccccc1 +Cn1nnnc1CNC(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1 +Cn1c(C2COCC2O)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O +Nc1nc(-c2cncnc2)cn2nc(-c3ccco3)nc12 +O=C1C2=C(C(=O)c3ccccc31)C1(CS2)NC(=O)C(Cc2ccc(O)cc2)NC1=O +O=C(CCCCCC(=O)NCc1cc(C(=O)NCc2ccccc2)c2cc(Br)ccc2n1)NO +Cc1ccc(C(=O)O)c(Oc2nc(Oc3cc(O)cc(-c4cccc(CN)c4)c3)c(F)cc2F)c1 +NC(=O)N1CCCc2cc(-c3cncc(-c4cccc(S(=O)(=O)NCCO)c4)c3)cnc21 +CNCC(Cc1ccccc1)N(C)CC(Cc1ccc(O)cc1)N(C)CC(Cc1ccc(O)cc1)N(C)C 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+Cc1cc(F)cc(C)c1N1CCN(Cc2cccc(C(F)(F)F)c2Cl)C(=O)C1=O +CCC(CC)C(=O)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)Cc1ccccc1 +CCc1c(Sc2ccccc2)n(OC(C)C)c(=O)[nH]c1=O +Cc1ncc(-c2ccnc(Nc3ccc(N4CCN(C(=O)CO)CC4)cc3)n2)n1C(C)C +O=C(Cc1c[nH]c2ccccc12)Nc1ncc(C2CCC2)s1 +O=S(=O)(c1ccc(C=Cc2ccccc2F)nc1)c1ccccc1F +c1ccc(-c2ccc(CNCCCNCc3ccc(-c4ccccc4)cc3)cc2)cc1 +COc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(=O)C(N)c1ccccc1)CC2 +O=C(O)CC(O)CC(O)CCn1c(C(F)(F)F)nc(-c2cccs2)c1-c1ccc(F)cc1 +CN1C2CCCC1CC(NC(=O)n1c(=O)n(C)c3ccccc31)C2 +CCC(=O)OC1=C(c2ccc(OC)cc2)Sc2ccccc2-n2cccc21 +Clc1ccc(-c2cc(Cl)cc3c2N2CCNCCC2C3)c(Cl)c1 +O=C1OCC2C1Cc1ccc(F)cc1C2C=Cc1ccc(-c2cccc(Cl)c2)cn1 +CCN1C(=O)c2c(nc(C(=O)OC)n2Cc2ccc(OC)cc2)N2C1=NC1CCCC12 +c1ccc(CCN2CCC(c3cc(-c4cccs4)[nH]n3)CC2)cc1 +CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1Oc1ccccc1 +CC(C)C1N=CC(=NOc2ccccc2)N1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CC(Oc1cccc(Cl)c1)C(=O)N(Cc1ccc(Cl)cc1)CC1CCCN1 +COC12C(COC(N)=O)C3=C(C(=O)C(C)=C(Nc4ccc(Br)cc4)C3=O)N1CC1NC12 +COc1ccc(-c2nc(C(C)(C)C)sc2CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc1 +COc1ccc(C(=O)NCC(c2cnc(C(F)(F)F)nc2)N2CCC(F)(F)CC2)c(Cl)c1OC +C=C(c1ccc(OC)cc1)c1nc(C)cc2ccccc12 +CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(CCc1ccc(F)cc1)CC2 +CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCC(N(C)C)C4)nc3)c2n1 +C[N+](CCCl)(CCCl)Cc1sccc1[N+](=O)[O-] +Cc1ccc(-c2cc(C(=O)NC(C)c3cnccn3)cc(N3C(=O)Cc4ccccc43)c2)cc1 +Oc1nc(SCCCCCCCCCc2ccccc2)ncc1Cc1cccnc1 +NC(=O)c1[nH]c2ccccc2c1S(=O)(=O)c1cc(Cl)ccc1N +CCCCc1nc2ccc(NCc3ccccc3)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCOC(=O)c1nc2c(O)nc3cc(Cl)c(-n4cnnc4)cc3n2n1 +CC(C(=O)OC1C[N+]2(CC(=O)Nc3cccc(F)c3)CCC1CC2)(c1cccs1)N1CCCCC1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2cc[n+]([O-])cc2)c1F +Cn1c(=O)c2nc(C=Cc3cc(F)cc(F)c3)[nH]c2n(C)c1=O +COc1cc2c(OCC3NC(=O)C4CC34)nccc2cc1C(N)=O +FC1(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CCNCC1 +CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3S(=O)(=O)c2ccc(F)cc2)CC1 +Clc1ccc2c(Nc3ccc(Nc4nc(NCc5ccccc5)nc(N5CCCCC5)n4)cc3)ccnc2c1 +COc1cc(OC)c2c(c1CO)CC1c3cc4c(cc3CCN1C2)OCO4 +Cc1cc(C)c(S(=O)(=O)NC(C)CNc2cc(C)cc3c2cnn3-c2cccc(NC(C)C(N)=O)c2)c(C)c1 +COc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 +Cn1cc(S(=O)(=O)NCCOc2cccc(C(Cc3ccccc3)CN3CCCC3)c2)cn1 +CN(CC1CCCc2cc(S(=O)(=O)c3cccc(F)c3)ccc21)C(N)=O +COc1ccc(Cl)cc1CNC(=O)NC(Cc1ccccc1)c1nc(-c2ccc3c(N)n[nH]c3c2)c(Cl)[nH]1 +COc1ccc(C(Cc2ccccc2)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)cn1 +COc1ccc(OC(F)(F)F)cc1Cn1c(C(=O)NCC(C)(C)O)cc2cc(C#N)ccc21 +Cc1nc2cc(NC(=O)c3ccc([N+](=O)[O-])s3)ccc2s1 +NS(=O)(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccc(Cl)cc2)cn1 +Cc1nc2cnc3cc(F)c(-c4ccc(Oc5cccc(CO)n5)cc4Cl)cc3c2n1C1CCN(C(=O)CO)CC1 +N#Cc1ccc(C2CCCCc3cncn32)c(-c2ccc(F)cc2)c1 +CCCN(CCN1CCN(c2ccccc2)CC1)C1CCc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2C1 +CC(=O)N1CCOc2cc(-c3cncc(F)c3)cnc21 +Nc1ncc(-c2ccc(C3(c4noc(-c5ccc(N6CCCC6CO)nc5)n4)CCC3)cn2)cn1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(F)c2)CC1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(-c3cncnc3)c2n1 +COc1cc(CCC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OC +Cc1c(OCC(=O)O)ccc(Sc2ccc(COc3ccc(C(F)(F)F)cc3)cc2OCC#N)c1C +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCCCCCc1ccccc1 +O=S(=O)(c1ccc(-c2cnc(C3CC3)o2)cc1)N1CCCSc2ccccc21 +CCOc1ccc(NC(=O)CCC(=O)n2nc(C)cc2C)cc1 +N=C(N)c1cccc(COc2ccc(C(=N)N)cc2Br)c1 +O=C(NC(CCCCCS)C(=O)NC1CCCC1)OC1CCCCC1 +CCCC(CCCN(CC)CC)Nc1c2ccccc2nc2ccccc12 +N#Cc1cnc(Nc2ccc3c(c2)CC(=O)N3)nc1NCc1ccccn1 +CCOC(=O)N1CCC(N2CCC(n3c(=O)[nH]c4ccccc43)CC2)CC1 +N=C(N)c1ccnc(-c2cccc(-c3cc(C(=N)N)ccn3)c2)c1 +c1ccc2c(c1)CCN(c1cc[n+](Cc3ccc(C[n+]4ccc(N5CCc6ccccc6C5)cc4)cc3)cc1)C2 +CC(C)Cc1cn(-c2ccc(C(=O)O)cc2)cc1C#N +Cn1c(=O)c2c(nc(C=Cc3cccc(NC(=O)CCCCC(=O)O)c3)n2C)n(C)c1=O +CCC(NC(=O)c1c(S(C)(=O)=O)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +CS(=O)(=O)C1(c2nc(-c3cc(F)cc4[nH]ccc34)nc3c2OCC2COCCN32)CC1 +CCN1CCCC1CNC(=O)c1c(O)c(Cl)cc(C)c1OC +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN1CCCCC1 +CCNC(=O)n1c(=O)n(Cc2nc3ccccc3n2CCC(C)C)c2ccccc21 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(COC3COC3)c12 +CCN(CC)CC(O)CNC1=NC(=NC(=N)Nc2ccc(Cl)c(Cl)c2)N=C(C)C1 +CCC1(c2cccs2)OCC(=O)N(C)c2ccc(-c3ccc(C#N)n3C)cc21 +CC1CCCN(CCC(C)N(C)S(=O)(=O)c2cccc3ccccc23)C1 +Cc1cc(C)c2ncc(NC(=O)Nc3c(F)cc(F)cc3F)c(-c3ccccc3Cl)c2c1 +COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(CCO)CC4)c(OC)cc23)c(Cl)cc1Cl +COC(=O)c1coc(CN2CCC(CNC(=O)c3n[nH]c4ccc(Br)cc34)CC2)n1 +CSc1cnc(-c2ccc(NC(=O)Nc3ccncc3)cc2)nc1N1CCOCC1 +Cc1c(Cn2c(C)nc3c(C(=O)O)cc(N4CCOCC4)nc32)cccc1C(F)(F)F +Nc1cc(C(=O)N2CCSCC2)cc2nc(-c3ccc(Br)o3)nn12 +Cc1nc(NC(=O)c2ccccn2)sc1S(=O)(=O)Cc1ccc(F)cc1F +CC(C)CC(S)C(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)O +COCc1nnc(-c2cnc(-c3ccc(C#N)cc3C)cn2)n1-c1ccc(OC)nc1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F)N1CCN(C(=O)N2CCCCC2)CC1 +O=C(c1nc2c(C(F)(F)F)cc(C3CC3)cn2c1Cl)N1CCC2(OCC3(CC3)CO2)C(O)C1 +C=C(COc1ccc(C(F)(F)F)cc1)COc1ccc(OCC(=O)O)c(C)c1 +CC(C)(C)CN1CC(c2nnc(C(=O)c3nc4ccc(-c5ccc(F)cc5)cc4s3)o2)C1 +NC(=O)C12CC3CC(C1)C(OC(=O)N1CCC(Nc4ncccc4C(F)(F)F)C1)C(C3)C2 +Cc1ccc(-c2cnc(Nc3cccc(N4CCNCC4)n3)s2)cn1 +COc1cc(OC)cc(C(=O)N(C)C2CCN(Cc3ccc4ccccc4c3)CC2)c1 +O=C(CCCCOc1ccccc1OCc1ccccc1)C(F)(F)F +CCCn1c(=O)ccc2c(-c3cnc(-c4ccc(C(C)C)nc4)s3)n[nH]c21 +CC(C)(C)c1ccc(C(=O)NCc2ccc(N)cc2Cl)cc1 +c1ccc(-c2ccc(N=c3ccn(CCCN4CCCCC4)c4cc(-c5cnc6ccccc6c5)ccc34)cc2)cc1 +O=C(CC1CCN(S(=O)(=O)Cc2ccccc2)CC1)N1CCC(C2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c32)CC1 +O=C(NCC1CCCCC1)C1Cc2c(sc3ccccc23)CN1 +CCCCN1CCCC1Cn1nc(Cc2ccc(Cl)cc2)c2cccnc2c1=O +Clc1ccc(-c2cncc(N3CC4CC(C3)N4)c2)c(Cl)c1 +COc1ccc(S(=O)(=O)N(Cc2cccc(C)c2[N+](=O)[O-])C(C)C(=O)O)cc1 +CCc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3cc(Cl)ccc32)ccc1OCCN1C(=O)CCC1=O +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCCc3ccccc3)ccc21 +Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2nccc3n[nH]c(C)c23)cc1 +CC(C)c1cccc(C(C)C)c1NS(=O)(=O)CC(=O)N(Cc1ccccc1)C(C)C +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1cccnc1Cl +CC(C)Sc1ccc(CC2CCN(C3CCN(C(=O)c4cccc5ccc(F)cc45)CC3)CC2)cc1 +N#CCCCn1c(Cn2c(=O)n(Cc3ccc(C#N)cc3)c3ccncc32)nc2ccccc21 +CC1(C)CCCN(C(=O)c2cccc(COc3c(Cl)cc(Cl)cc3Cl)n2)C1 +Nc1cccc(Nc2ncnc3c2ncn3CCOc2ccccc2)c1 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+CC(=O)c1ccc2nc(-c3cc(-c4cnn(C5CCNCC5)c4)cnc3N)oc2c1 +O=C1OC(Nc2ncc3nnn(-c4ccccc4)c3n2)c2ccccc21 +COc1ccccc1C(=O)N1CCN(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1 +Nc1ncnc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)c1C=NOC1CCCC1 +COc1cccnc1Cn1ccc2nc(N)nc(NCc3cc(C)on3)c21 +Nc1ccnc(N2CCC(NC3CC3c3ccccc3)CC2)n1 +Cn1c(-c2cn(CCO)nn2)nc(-c2ccc(F)cc2)c1-c1ccncc1 +CCN=C(NC#N)C1=CC(C)(C)Oc2ccc([N+](=O)[O-])cc21 +COc1cc(O)c(-c2c(C)cc(O)c3c(OC)cccc23)c2c1C(C)N(C)C(C)C2 +O=C(NCc1ccccc1)OC(CCl)COc1cccc(C(F)(F)F)c1 +COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2F)CC2CCC1C2 +C[S+]([O-])CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 +COC1Cc2sc(C#N)cc2C2(CCN(Cc3ccccc3)CC2)O1 +COc1cccc(C2C3C(=O)N(c4ccc(C(=O)O)cc4)C(=O)C3ON2c2ccc(C)cc2)c1 +CC1(C)C(C(=O)O)N2C(=O)C(CS)C2S1(=O)=O +CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 +Nc1ccc(C2OC3CC(=O)OC3C3=C2C(=O)c2ccccc2C3=O)cc1 +N#CC(Cc1ccc(-c2cnn(C3CCOCC3)c2)cc1F)NC(=O)C1NC2CCC1C2 +COc1ccccc1NC(=O)c1cn2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc2n1 +CCS(=O)(=O)N(Cc1ccc(F)c(F)c1)c1sc2ccccc2c1C=O +COc1ccc(N=Cc2c(N)ncnc2Nc2ccc3c(cnn3Cc3cccc(F)c3)c2)cc1 +O=C(Nc1ccc(OCc2ccccc2)cc1)C(O)C12CC3CC(CC(C3)C1)C2 +Cc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)NCCCCCCNc1c2c(nc3ccccc13)CCCC2 +COc1cc2[nH]c(=O)c(-c3cccs3)c(-c3cccc(-c4ccccn4)c3)c2cc1OC +COc1ccc(-n2c(C)nnc2SCC(=O)Nc2ccccc2Br)c2ccccc12 +NCCCNCCCCCCCCNC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccncc1 +NC(=O)c1cccc(NCCCN2CCN(c3ccccc3)CC2)c1 +O=[N+]([O-])c1cccnc1N1CCC(=CC#Cc2ccccn2)CC1 +O=C(c1ccc(CCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +Cc1ccc(-c2c(O)nc3cc(Cl)c(NC(=O)NC4CC4)cc3c2OCCC2CCCCN2)cc1C +O=C(c1cc2cc(Cl)ccc2o1)N1CCCC1CN1CCCC1 +CCCC(=O)NC(Cc1ccc(O)cc1)C(=O)NCCCCCNCCCCCCCCCCCCN +COc1ccccc1C=CC(=O)Nc1nc(N)n(-c2ccccc2)n1 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)c3ccccc3C)CC2)cc1 +Cc1ccc(C(=O)N2CCC(=CC(=O)NC3CCN(Cc4ccc5cc(F)ccc5c4)C3)CC2)c(O)c1 +Cc1nc(N2CCCCC2)c2[nH]c(-c3ccccc3Cl)cc2n1 +O=C(NC(Cc1ccccc1)C(O)CN(OC1CCCC1)S(=O)(=O)c1ccc2c(c1)OCCO2)OC1COC2OCCC12 +CCOC(=O)C(C)(CC(C)C)c1ccnc2c(-c3ccc(Cl)cc3)cnn12 +O=c1[nH]c(N2CCC(c3ccccc3)CC2)c(Cc2ccccc2)c(=O)[nH]1 +O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2c(Cl)cccc2Cl)CC1 +CCc1ncc(Cc2cnc3ccccc3c2)c2cc(OC)c(OC)cc12 +NC1=NC2(CCO1)c1cc(NC(=O)c3cnc(O)cn3)ccc1Oc1ncc(Br)cc12 +CCOc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 +Cc1c(-c2cccc(O)c2)c(=O)n(CCN(C)CCc2ccccn2)c(=O)n1Cc1c(F)cccc1F +O=C(NCCCCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1)c1ccccc1 +CCN(CC)Cc1ccc(-c2cc(S(=O)(=O)CC)ccc2OC)[nH]1 +O=C(Nc1ccc(-c2nc3cc(NC(=O)C4CCCCC4)ccc3[nH]2)cc1)c1ccc(Cl)c(Cl)c1 +COc1ccccc1N1CCN(CCNS(=O)(=O)c2cccc3c(N(C)C)cccc23)CC1 +Nc1sc(-c2ccc(F)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CC1 +O=C(CCC(=O)N1CCN(CC2CC2)CC1)c1ccc(Cl)cc1 +COc1cccc(CN2CCCC3(CCN(c4cnc5ccccc5n4)CC3)C2=O)c1OC +COc1cc(-c2cc(Cl)cnc2OC)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccnc(C)n3)ccc21 +C[N+](C)([O-])CCNc1ccc2nnn3c4ccccc4c(=O)c1c23 +CCCCC(CC)N(Cc1ccc(C(=O)NCCC(=O)O)cc1)C(=O)Nc1ccc(OC(F)(F)F)cc1 +OCC1NC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O +Cc1ncc([N+](=O)[O-])n1CCNC(=S)NCc1ccc(S(N)(=O)=O)cc1 +CC(C)(C)CNC(=O)CC(NC(=O)CCc1ccccc1)C(=O)NC(CCc1ccccc1)C(=O)NCC1CC1 +O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1)c1ccncc1 +NC(CC(=O)N1C(C(=O)NC2CC2)CC2CCCCC21)Cc1cc(F)c(F)cc1F +O=C(CC1CC1)N1N=C(c2cccnc2)CC1c1ccccc1O +O=C(O)CC1CCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 +N#CC1(n2cc(C(NC(=O)c3ccc(C(N)=O)cc3)C3CCCCC3)nn2)CC1 +O=C(Nc1ccc2c(c1)OCO2)c1cc2cc(C3(O)CCN(CCCc4ccccc4)CC3)ccc2o1 +COCCOc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)cc3)c2cc1NC(=O)C=CCN(C)C +COc1cccc(CNC(=O)c2cn(-c3ccccc3)c3cc(-c4cn[nH]c4)ccc23)c1 +O=C(OC1CCN(c2ccccn2)CC1)N1CCN(C2CCC2)CC1 +O=C1NCCCCC1N(Cc1csnn1)S(=O)(=O)c1ccc(Cl)cc1 +CN(Cc1ccccc1)C(=O)C(Cc1ccccc1)NC(=O)C1CCC(O)CN1C(=O)c1c[nH]c2ccccc12 +CN(C)c1ccc(C=Cc2cc3cc(I)ccc3o2)cc1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NC(C)C(N)=O)[nH]c3ccc(Cl)c(F)c23)c1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1cccc(NC(=O)NCCCN2CCC(C3CCCCC3)CC2)c1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Oc3cccc([N+](=O)[O-])c3)n2)n[nH]1 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+O=C1C(Cl)=C(Nc2ccccc2C(F)(F)F)C(=O)c2c1cccc2[N+](=O)[O-] +CCn1ccc2ccc3c4[nH]c5ccccc5c4c4c(c3c21)C(=O)NC4=O +CCN(CC)CCn1nc2c3c(c(NCCNCCO)ccc31)C(=O)c1ccccc1-2 +CS(=O)(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1F +N#Cc1c(Cc2ccc(S(N)(=O)=O)cc2)c(-c2ccccc2)nn1-c1nc(C(=O)O)cs1 +OC1(c2ccc(Br)cc2)CCN(Cc2cc3ccccc3o2)CC1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2cnco2)s1 +COc1cc(OCc2cccc(OCc3ccccc3F)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CNc1nc(NCCCN(C)C)c2sc(-c3ccc(NS(C)(=O)=O)cc3)cc2n1 +CSc1sc(C(=N)N)cc1-c1csc(Nc2ccc(Cc3ccccc3)cc2)n1 +O=C(Nc1nc2c(s1)CC(N1CCOCC1)CC2)c1cccc(C2CCCN2C(=O)c2ccc(-n3ccnc3)cc2)c1 +Cc1ccc(F)cc1Oc1c(C(=O)N2CCNCC2)c2ccc(O)cc2n1-c1ccc(F)cc1 +COc1ccccc1-n1nnc(C)c1C(=O)N1CCN(c2ccc([N+](=O)[O-])cc2Cl)CC1 +O=C(O)CNC1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +Cc1noc(C)c1-c1ccc(-c2nc3ccccn3c2NC(C)(C)C)cc1 +Cc1cccc(-c2ccc3c(c2)SCc2c-3nc3ccc(F)cc3c2C(=O)O)c1 +CS(=O)(=O)c1ccc(-c2cnc(C#N)n2-c2ccc(F)cc2)cc1 +COc1cc(-c2nc(-c3cc(C)nc(C)c3)c3n2CC(CF)OCC3)ccc1OC(F)F 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+N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1F +Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCN)cc3)ccc2n1 +O=C(O)c1cncc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nn2)c1 +CCCc1cc2c(C(F)(F)F)cc(=O)oc2c(CCC)c1OCCCCN1C(=O)NC(C)(c2ccc(OC)cc2)C1=O +Cc1c(N(CCC2CC2)S(=O)(=O)c2ccc(C(=O)O)cc2)sc2ccccc12 +COc1ccc2c(NC(=O)N3C(C(=O)NCc4cccc(Cl)c4F)CC4CC43)cn(C(N)=O)c2c1 +O=C(c1ccco1)c1cnn2c1n[n+]([O-])c1ccc(-c3ccco3)cc12 +Cc1cc(C(N)=O)ccc1-n1c(CCC(=O)O)ccc1-c1cc(-n2ccnc2)cs1 +Cc1ccc(C(=O)NCc2ccccc2)cc1Nc1nc(NC2CCNC2)nc(N(C)CC(C)(C)C)n1 +O=C(O)c1ccc(Cn2[nH]c(=O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)cc1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCCN(Cc2cccc3c2OCCO3)C1 +CN(C)CCS(=O)(=O)Nc1ccccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 +Cc1cnc(CNC(=O)c2ccc(NC(=O)N3Cc4ccc(F)cc4C3)cc2)o1 +CCOC(=O)N1C2CCC1CC(Oc1ncnc(Oc3cccnc3C)c1C)C2 +CN(CCCOc1ccc2cc(-c3ccc(Cl)cc3)c(=O)oc2c1)Cc1cccc(OC(=O)NCCCCCc2ccccc2)c1 +CCCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cccc(-c3ccccc3)n2)CC1 +CCCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NCc2ccn3nccc3n2)C2CCCC2)nn1 +CC(=O)N1c2cccc(O)c2NC2=C(C(=O)CC(C)(C)C2)C1c1ccc(Oc2ccccc2)cc1Cl +CN1CC(c2cccc(F)c2F)CCC(NC(=O)c2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)C1=O +O=C1OCC(C2CCNCC2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +O=C(NCC1CCOCC1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +O=c1c2ccccc2ccn1CCCCN1CCN(c2cccc3sccc23)CC1 +CCC(NC(=O)c1c([S+](C)[O-])c(-c2ccccc2)nc2cc(Cl)ccc12)c1ccccc1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1cn(C)c3ccccc13)CC2 +CN(c1ccc(OCCCCC(=O)NO)cc1)c1ncnc2ccccc12 +COc1cc2[nH]ncc2cc1Nc1ncnc2[nH]c3c(c12)CC(C(=O)NCc1ccccc1)CC3 +COc1ccc(OC)c(N(C)Cc2cnc3nc(N)nc(N)c3n2)c1 +Cc1cc(C)cc(-c2[nH]c3c(c2C(C)CNCCc2ccncc2)CN(C(=O)C2C(C)(C)C2(C)C)CC3)c1 +Cc1ccc(OCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 +CCCCNC(=O)CCn1nnnc1C(COCc1ccccc1)NC(=O)C(C)(C)N +CC(C)CC(NC(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)C(=O)O +O=C(Cc1csc(NC(=O)c2ccc3ccccc3n2)n1)NO +COc1ccc2nc(SCC(=O)Nc3ccc(S(N)(=O)=O)cc3)n(Cc3ccccc3)c(=O)c2c1 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+CC(C)(C)C(=O)NC(C(=O)NO)c1ccc(-n2cccn2)cc1 +CCN(C)CC#CCCC1(C2(O)c3ccccc3Sc3ccccc32)SCCCS1 +CC(C)C(C(=O)O)N1C(=O)C2Cc3ccccc3CN2C1(C)C +CC1=CCCC2(C)OC2C(=O)C2CCC(C)C(C)(CC1)C2COc1ccon1 +N=C(N)c1ccc(C#Cc2cc3ccc(C(=N)N)cc3[nH]2)nc1 +CC(C)COc1cccc(CN2CCN(C(=O)Nc3ccccc3)CC2)c1 +CC(C)(C)c1cc(NC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)no1 +CCOc1ccc(C#Cc2ccc(CC(C)NC(=O)C3(C)CC3)cc2)cc1 +O=C(Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1)C1CCNC1 +CCN1CCCC1CNC(=O)c1cc2cc(Br)ccc2cc1O +Cc1noc(-c2ccc(Nc3nn(C4CCCCC4C#N)cc3C(N)=O)cc2)n1 +COc1ccc(-c2ccc3[nH]nc(-c4cc(N5CC(C)OC(C)C5)ncn4)c3c2)cn1 +CC(C)c1cccc(CNCC(O)C(Cc2ccccc2)NC(=O)C2CCCC(C(C)(C)N3CCCC3=O)C2)c1 +O=C(NN=Cc1cccc2c1ccn2Cc1ccc(C(F)(F)F)cc1)c1ccc(O)c(Cl)c1 +CC1CCC(C)N1CCc1c[nH]c2ccc(-c3cccs3)cc12 +CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(CCC(c2ccccc2)c2cccc(Cl)c2)CC1 +CC(C)(O)c1ccc(C(CNC(=O)c2cccc(Cl)c2Cl)CC2CC2)cn1 +COc1cc(C(=O)NN2c3ccccc3N=C(N3CCN(C)CC3)c3cc(Cl)ccc32)cc(OC)c1OC +CC(C)(C)NC(=O)C1CCC(n2cc(C(N)=O)c(Nc3ccc(Cl)cc3)n2)C(C#N)C1 +CCc1ncc(C(CNC(=O)c2ccccc2Cl)N2CCC(F)(F)CC2)cn1 +Nc1noc2cccc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 +COc1ccccc1-c1cn(CCC(O)CN2CCN(c3ccccc3OC)CC2)nn1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3cc(C(=O)NC(C)C)[nH]c23)cc1 +O=C(Nc1ccc(F)cc1)c1cnc(N(Cc2ccccc2)Cc2ccc(B(O)O)cn2)nc1 +CCCC(=O)NC(c1ccccc1OC)c1ccc2cccnc2c1O +Cc1nc(C)c(-c2ccnc(Nc3cccc(F)c3)n2)s1 +COc1ccc(C2(c3cc(OC)c(OC)c(OC)c3)CC(C#N)=C(c3ccc(F)cc3)O2)cc1O +Cc1cc(-c2cc(C)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccncn5)ccc43)cc2F)ccc1Cl +O=C(NCc1cccnn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CC(C)Oc1ccc(NC(=O)N2CCN(c3ncnc(N)c3C=NOCC(=O)N3CCOCC3)CC2)cc1 +CCN(CC)CCNCc1cc(C(N)=O)c2ncnc(NCc3cccc(NC(O)c4ccc(OC)cc4)c3)c2c1 +Cc1cc(C)cc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Br)cc2C)c1 +c1ccc(CN(CCCCN(CC2Cc3ccccc3CN2)C2CCCc3cccnc32)Cc2ccccc2)cc1 +O=c1[nH]c2c(O)ccc(C(O)CNCCSCCCNCCc3cccc(Cl)c3Cl)c2s1 +CCCC1CCC(N2CCC3(CC2)C(=O)NCN3c2ccccc2)CC1 +c1ccc(CNc2sc3ncnc(N4CCC(COCCN5CCCC5)CC4)c3c2-c2ccccc2)cc1 +Cc1c(=O)n(Cc2ccccc2)c(=O)n2cc(C(=O)N3CCC(Oc4ccccc4C(F)(F)F)C3)sc12 +CC(C)(C)C(=O)Oc1ccc(S(=O)(=O)Nc2ccccc2C(=O)OCCO)cc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cc(Br)ccc3O)NC(=O)NC1=O)C2 +Fc1cccc(Cl)c1-c1nc(-c2ccc(CCc3ccccc3)cc2)c[nH]1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NC(C)CC(N)=O)[nH]c3ccc(Cl)c(F)c23)c1 +CCCCNC(=O)NS(=O)(=O)c1ccc(Oc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc1 +CCc1nn(C2CC2)c2c1C(c1ccc(Cl)cc1)N(c1cc(C)c3nnc(C)n3c1)C2=O +c1ccc(-c2nnc3sc(-c4ccc5c(c4)OCO5)nn23)nc1 +Clc1ccc(COC(Cn2cccc2)c2ccc(Cl)cc2Cl)cc1 +CCCC1(CC(=O)O)OCCc2c1[nH]c1c(Cl)ccc(Cl)c21 +CN(C(=O)Nc1ccccc1)C1CC(C(=O)O)Nc2cc(Cl)cc(Cl)c21 +FC1(F)CCC(NC(=S)c2cnc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)n2)CC1 +N#Cc1ncc2nc1OCCCCCOc1cc(OCc3ccccn3)c(Cl)cc1NC(=O)N2 +O=C(Cc1ccc2ccccc2c1)n1sc2ccccc2c1=O +c1cc(CNc2ncnc3ccsc23)cc(Nc2nc3ccccc3[nH]2)c1 +COc1cccc(Cn2c(=O)n(CC3CC3)c(=O)c3c2nc2cc(OC)ccn23)c1 +CCN(CC)CCNC(=O)c1cc(C=C2C(=O)Nc3cc(-c4cccc(O)c4)ccc32)[se]c1C +Nc1nc2ccc(C(=O)c3ccccc3)cc2n1CC1CCNCC1 +CCN(CC)CCCOC(=O)Nc1cccc(CN2N=C(c3ccc(Cl)cc3)CSC2=O)c1 +Nc1cccc(Nc2nc(NCCO)nc(NCCCCNc3nc(NCCO)nc(Nc4cccc(N)c4)n3)n2)c1 +CCN(CC)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(C(=O)N2CCCCC2)cc1 +COc1cc(CCc2ccc(C3=Cc4ccccc4C4=NCCN34)cc2)cc(OC)c1OC +O=C1c2c(ccc(O)c2O)CN1Cc1ccc(F)c(Cl)c1 +COc1ccc2c(c1)-c1ncnn1Cc1c(C)ncn1-2 +Cc1cc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)sn1 +O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1ccc(F)cc1 +CCOC(=O)C(C#N)C(c1ccccc1C(F)(F)F)c1cccc2ccccc12 +CCCNC1CCN(c2ccc(NC(=O)C(C)(C)c3ccccc3)cc2Cl)CC1 +Cn1cc(C2=C(c3cccc(N)c3)C(=O)NC2=O)c2ccccc21 +N#CC1(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)CCCC1 +CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc32)ccc1OC(C(=O)O)c1ccccc1 +CCCS(=O)(=O)Nc1cc(F)cc(C(=O)Nc2cnc3[nH]ccc3c2)c1F +O=C(O)c1ccc(Cl)cc1OCCN1CCC(c2cn(Cc3ccoc3)c3ccccc23)CC1 +COc1cc(OCC2CCCCC2)c(F)cc1CNC(=O)C1CCCN1 +O=C1Nc2c(ccc(F)c2F)C1(c1ccc(O)cc1)c1cccs1 +CC(C1CN(C(=O)OC(C)(C)C)CCN1C(=O)Cc1ccc(Cl)c(Cl)c1)N1CCCC1 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+O=C(O)c1cc(-c2cccs2)nc2c1cnn2Cc1ccncc1 +O=c1[nH]cnc2c(CNC(CO)C(O)CO)c[nH]c12 +COc1cc2c(Nc3c(F)ccc(O)c3C)ncnc2cc1OCCN1CCCCC1 +C=CCN(C)CC=CCOc1ccc2c(-c3ccc(Br)cc3)coc2c1 +C(#Cc1ccc2c(c1)OCO2)CON=C1CN2CCC1C2 +CCn1cc(-c2cn3ncc(C(N)=O)c(NC4CN(C(=O)C5(C#N)CC5)CC4CF)c3n2)cn1 +Fc1ccc(-c2ncc(C3CCN(Cc4ccn(-c5ccc(C(F)(F)F)cc5)c4)CC3)[nH]2)cc1 +CCn1ncc(-c2ccncc2)c1-c1ccc(OCc2ccc3ccccc3n2)cc1 +CNC1CCN(c2nc(N)nc3c2sc2cc(Cl)ccc23)C1 +COc1ccc(C(=O)c2cn(C)c3c(OC)c(OC)c(OC)cc23)cc1O +CC(=O)OC1C(C)CC(Oc2c(-c3ccc(O)cc3)oc3cc(O)cc(O)c3c2=O)C(O)C1OC(C)=O +COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +COc1ccc(-c2cccn3nc(Nc4cnn(C(C)CO)c4)nc23)cc1 +O=C(Nc1ccccc1)N1CCN(Cc2cccc(-c3ccccc3)c2)CC1 +COc1ccc(NC(C)=O)cc1-c1nn(C(C)c2ccc(Cl)cc2)c(=O)c2c(C)noc12 +Cc1ccccc1Nc1cc(-c2ccnc(Nc3ccccc3C)c2)ccn1 +COC(=O)c1cccc(-n2cc(-c3nc(-c4ccc(F)cc4)c(-c4ccncc4)n3C)nn2)c1 +CS(=O)(=O)c1ccc2c(c1)C(=O)NC(C(=O)NC1(C#N)CC1)Cc1ccc(c(Cl)c1)OCC=CCO2 +CC1(C)C(=O)C(C#N)=CC2(C)C3=CCCC(O)C3(C)CCC12 +CCC(CS(C)(=O)=O)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(C)OCC2Cc2cccc(-c3ncccn3)c2)c1 +Cc1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 +CC(O)Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 +O=C(O)CC(CC1CCN(C(=O)CCc2ccc3c(n2)NCCC3)CC1)c1cccc(F)c1 +CN(C)C1CCN(C(=O)c2ccc(Cn3cnc4ccccc43)cc2)C1 +O=C1C(CC(F)(F)F)=CC(O)(CSc2ncccn2)N1CCNc1ccnc2cc(Cl)ccc12 +CC(C)n1c(=O)n(C(=O)NCN2CCN(C)CC2)c2ccccc21 +CC(NCCc1cccc(Br)c1)c1cccc(COc2nn3c(C(F)(F)F)nnc3c3ccccc23)n1 +C#CCN(C)CC(=C)c1cccc(COc2ccccc2)c1 +O=C(O)C1=C(C(=O)Nc2ccc(-c3cccc(OC(F)(F)F)c3)cc2Cl)CCC1 +Cc1noc(-c2cc(NCCN3CCCC3)c(C)c(N3CCN(c4ncnc5[nH]nc(Br)c45)CC3)c2)n1 +COC1(c2cc(F)cc(OCc3ccc4c(c3)C(C)(C)C(=O)N4C)c2)CCOCC1 +COc1ccc2cc(C(=O)NCCCCCCCNc3c4c(nc5ccccc35)CCCC4)c(=O)oc2c1 +O=C(NC(Cc1ccccc1)C(O)CN(OC1CCCC1)S(=O)(=O)c1ccc(O)cc1)OC1COC2OCCC12 +O=C(NOCc1ccccc1)c1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 +CCOC(=O)CNc1cccc(Nc2ncc(F)c(Nc3cccc(O)c3)n2)c1 +CN(C)S(=O)(=O)c1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +O=C(O)c1ccccc1NC(=O)N1CC2CC(c3ccccc3C(F)(F)F)CC2C1 +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)Nc5ccc(F)cc5C(F)(F)F)cn4c3)cc2)CC1 +COc1cnc2c(C(=O)Nc3cc(Cl)ccc3N3CCC(CO)CC3)cnn2c1 +CC(C)(Cc1cccc(CC(=O)NCc2ccc(O)cc2Cl)c1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1 +CN(C)CCNC(=O)c1cc(NC(=O)CCC(=O)Nc2cc(CO)cc(Nc3c4ccccc4nc4ccccc34)c2)cn1C +Cc1cc(NS(C)(=O)=O)ccc1-c1cnccc1OCC(F)(F)F +CCCNC(=O)c1ccccc1CCC1(O)CCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C +Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3ccc(OCCN4CCOCC4)cc3)n2)cc1 +CN(C)C12CCN(CCN)C(C(c3ccc(Cl)cc3)C1)C(c1ccc(Cl)cc1)C2 +CNCC(O)C(c1ccccc1)n1c(=O)n(C2CCC2)c2ccccc21 +COc1ccc(CNc2nccc(-c3c(-c4ccc(F)cc4)ncn3Cc3cccc(C#N)c3)n2)cc1 +CCCCc1ccc(C2=NN(P(=O)(OC)c3ccccc3)CCC2)cc1 +CCC(C)(C)c1ccc(C=CC(=O)Nc2ccc3c(c2)OCCO3)cc1 +COCCn1ccc(-c2nc(C)nc3c2CC(C)N(C(=O)c2cccc(C(F)(F)F)c2Cl)C3)n1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(c2ccc(CO)cc2)CCCC1 +COC12CCC3(CC1COCc1ccccc1)C1Cc4ccc(C#N)c5c4C3(CCN1C)C2O5 +O=C(c1ccccc1)c1cc(C(=O)C(F)(F)F)n(-c2cnn(O)c2)c1 +CS(=O)(=O)Nc1cc(Cl)cc(-c2[nH]c(C3CC3)nc2-c2ccnc(N)n2)c1F +CNC(=O)C1OC(n2cnc3c(NCc4cccc(I)c4Cl)ncnc32)C(O)C1O +N=C(NC(=N)N1CCN(C(=N)NC(=N)Nc2ccc(Cl)cc2Cl)CC1)Nc1ccc(Cl)cc1Cl +CCNc1nc2ccc(OC)cc2cc1Cc1c(=O)[nH]c(CNS(C)(=O)=O)c2cc(OC)c(OC)cc12 +CC(c1ccccc1)n1cncc1C(=O)OCc1ccc(C(=O)c2ccccc2)cc1 +COC1COCCC1NC1CCC(C(=O)N2CCN(c3nncc(C(F)(F)F)n3)CC2)(C(C)C)C1 +COc1ccc2c(c1)CCC(NCC1CCC(CNS(=O)(=O)c3ccc4ccccc4c3)CC1)C2Cc1ccccc1 +COC(=O)C1C(OC(c2ccccc2)c2ccc(Cl)cc2)CC2CCC1N2C +CN(Cc1ccc(-c2ccc(Cl)cc2)cc1)C(=O)CCCn1cc(Cc2cnn(C)c2)c(=O)nc1SCc1ccc(F)cc1 +O=C(CCC1=CCN(CCCc2ccc3ccccc3c2)C1=O)NO +Cc1c(CCCl)sc[n+]1CCCCCCCCCCCC[n+]1csc(CCCl)c1C +CN1C(=O)Cc2cc(S(=O)(=O)NNc3ccc(Br)cc3)ccc21 +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1nc(Nc2ccc(N3CCN(C(C)=O)CC3)cc2)ncc1F +Nc1nc2ccccc2c2c1ncn2C1OC(COS(=O)(=O)NC(=O)CCCCC2SCC3NC(=O)NC32)C(O)C1O +Cn1cc(-c2cnc3nnn(Cc4ccc5nccn5n4)c3n2)cn1 +Cc1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCC(O)CC1 +Cc1cc(C)c(C=C2C(=O)Nc3ccc(C(=O)NC(CO)c4ccccc4)cc32)[nH]1 +Cc1nc(N2CCCCC2)c2[nH]c(-c3ccccc3)c(-c3ccccc3)c2n1 +COc1cc([S+]([O-])c2ccccc2)cc2c3c(oc12)CCNC3 +CNC(C)C(=O)NC(C(=O)N1c2ncccc2CC1CNC(=O)N(C)C)C(C)C +O=[N+]([O-])C=C1NC=CN1Cc1ccc(Cl)nc1 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC(F)(F)c2ccccc2)C(=O)C(O)CO)c1 +Cc1onc(-c2c(Cl)cccc2Cl)c1NC(=O)OCc1c(F)cccc1Cl +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(C34CCC(CC3)CC4)n2)cc1OC(F)F +CCCCCCOc1c(O)cc(Br)c2c1CN1CCc3cc(OC)c(O)cc3C1C2 +CC(C)CC(NC(=O)C(Cc1cccc2ccccc12)N(C)C(=O)OCc1ccccc1)B(O)O +O=c1[nH]nc(-c2ccnc(NC3CCCCC3)c2)n1-c1ccc2ccccc2c1 +O=C1NC(=O)c2c1c1c3ccc(F)cc3[nH]c1c1c2c2cccc3c2n1CCNC3 +NC1CCN(c2cncc(-c3cc4c(-c5ccccc5F)n[nH]c4cn3)c2)CC1 +CCN1CCCC1CNC(=O)c1c(OC)ccc(S(N)(=O)=O)c1I +CC1(C)C(NC(=O)c2cnccn2)C(C)(C)C1Oc1ccc(C#N)c(Cl)c1 +CCC(C)c1cc2c(C(F)(F)F)cc(=O)[nH]c2cc1N +CCCCN(CC)C1C=C(C(=O)O)CC(N)C1NC(C)=O +CC(C)(CC(O)(Cc1cc2cc(S(C)(=O)=O)ncc2[nH]1)C(F)(F)F)c1ccccc1S(N)(=O)=O +C=C(F)C(=O)Nc1cc(-c2ncnc3[nH]cc(C(=O)OCC)c23)ccc1F 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+CC(C)Cc1cc2c(s1)CNC1CCc3cc(O)c(O)cc3C21 +CCOC(=O)COc1ccc(-c2cc3cc4c(cc3o2)OC(C(C)(C)O)C4)cc1 +O=C(NC(c1ccncc1)c1ccc(Cl)cc1)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1 +O=C(Nc1ccc(CN2CCCC2)cc1)c1sc2ncnc3c2c1[nH]c(=O)n3-c1ccc(F)c(Cl)c1 +O=C(Nc1ccc(CNc2nc(N3CCC3)nc3ccccc23)cc1)c1ccc(F)cc1 +CC1=NC(=S)N(C(=O)OC2CCN(Cc3ccccc3)CC2)C(c2ccccc2[N+](=O)[O-])C1=C(O)OC(C)C +NS(=O)(=O)c1cc(F)ccc1NS(=O)(=O)C=Cc1ccc2ccccc2c1 +CN1C(=N)NC(C)(c2cc(-c3cccc(-c4nnco4)c3)cs2)CS1(=O)=O +COc1cccc(C(=O)N(c2ccccn2)C2CCN(c3cc(N)ccn3)CC2)c1 +CNC(=O)COc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +CC1(c2sc(C(=O)NCc3ccsn3)cc2Cl)CS(=O)(=O)C2(CCCCC2)C(=N)N1 +COc1cc(OC)nc(NCCn2cc(NC(=O)c3ncoc3-c3ccccc3F)cn2)n1 +CCCn1c(=O)c2[nH]c(-c3cnn(Cc4ccccc4)c3)nc2n(CC)c1=O +C=CCN1CC(C)N(C(c2cccc(O)c2)c2cccc(C(=O)N(C)Cc3ccccc3)c2)CC1C +CN(C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1)c1ccccc1 +C=Cc1cc(Nc2cc(=O)n(CCCCOC)c(=O)[nH]2)ccc1C +CC(C)(C)CCc1ccc(-c2cc3cn(C4CC(O)C(CO)O4)c(=O)nc3o2)cc1 +COc1ccc(C2CN(C)CC2NC(=O)c2ccc3cnc(Nc4cc(C)nn4C)cc3c2)cc1 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+COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(OC(F)(F)F)c(F)c4)cc3)c(=O)c2cc1Cl +CC(C)(C)OC(=O)N1CCC(CN(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Nc1ncccc1-c1noc(CCC2(c3ccccc3)CCCCC2)n1 +O=S(=O)(c1ccccc1)N(Cc1ccc(C(F)(F)F)c(F)c1)c1nc2ccccn2c1Br +CC(C)COc1ccc(-c2cc(C(=O)O)nc(N)n2)cc1C#N +O=C(c1c(Oc2cccc(F)c2F)n(-c2ccccc2)c2cccnc12)N1CCNCC1 +O=c1nc(N2CCOCC2)cc(N(CCO)Cc2cccc3ccccc23)[nH]1 +COc1cc(Nc2nc(N)n(-c3ccccc3)n2)ccc1-c1cnco1 +CCCc1c(OCc2ccc(Oc3ccc(-c4nn[nH]n4)cc3)cc2)ccc2c1ccn2CC(C)(C)C +NC(=O)c1cncc(OCc2cccc(NC(=O)C=Cc3ccccc3)c2)c1 +NC1CCC(NC2CC2c2ccc(-c3cccc(C(F)(F)F)c3)nc2)CC1 +Cc1ccc(NC(=O)N(CCCN2C3CCC2CC(n2c(C)nc4c2CCN(C(=O)C2CCC2)C4)C3)c2ccccc2)cc1 +COc1c(C)c[n+]([O-])c(Cn2cnc3c(Cl)nc(N)nc32)c1C +O=c1oc(N2CCOCC2)nc2sc3c(c12)CCN(Cc1ccccc1)C3 +N#Cc1cc(-c2n[nH]c3ccnc(OC4CCOCC4)c23)ccn1 +N=C(N)c1cccc(N2CCCCN(C3CCN(S(=O)(=O)c4ccccc4N)CC3)C2=O)c1 +COc1ccc2c(c1)CCN1CC3CCCN(S(C)(=O)=O)C3CC21 +O=S(=O)(NCCCCCCCCn1cc(-c2cccnc2)nn1)c1ccccc1Br +FC(F)(F)Oc1ccc(Nc2cc(NCCN3CCOCC3)ncn2)cc1 +COc1ccc(C(C)(NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)Nc2ccc(OC)c(OC)c2)cc1 +O=C(O)c1c(CCCOc2cccc3c2CCCC3)c2cccc3c2n1CCS3 +Cc1ncc(C)c(-c2ccc(N(Cc3ccsc3)C(=O)c3ccc(O)cc3O)cc2)n1 +Clc1ccc(C(c2ccc(Cl)cc2)(c2cncs2)n2ccnc2)cc1 +O=C(NCc1cccnc1)c1cc2n(n1)CCN(Cc1ccc(Cl)c(Cl)c1)C2=O +CC(Oc1nnc(-c2ccn(C)c(=O)c2)n1C)c1cc(-c2cccc(Cl)c2)on1 +CNC(=O)C1CC=C(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +CC1CCC(CC(C(=O)NC(CCCN=C(N)N[N+](=O)[O-])C(=O)Nc2nccs2)C(C(C)C)N(O)C=O)CC1 +O=C(Nc1ccc(OC(F)(F)F)cc1)NC1CCN(C(=O)c2ccncc2)CC1 +O=C(O)c1cnc(C(=O)CCc2ccc(-c3ccccc3)cc2)o1 +Cc1ccccc1-c1nnc(-c2nnn(-c3ccccc3)c2C)o1 +CC1CCC2C(C1)c1cc3c(C(F)(F)F)cc(=O)n(C)c3cc1N2C +CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C(C)(C)O)cc2C)c1C +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccc(C#N)cn23)n1 +Cn1c(N2CCNC(c3ccccc3Cl)C2)nc(-c2ccncn2)cc1=O +COc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1-c1ccnn1C +Cc1ccc2c(c1)c(S(=O)(=O)c1ccccc1Cl)c(C)n2CC(=O)O +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2C2CCCC2)c1 +CCc1ncnc(N2CCC3(CC2)OCCO3)c1C#Cc1ccc(N)nc1 +O=C(O)C(Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccc(O)cc4O)sc4ccccc34)cc2)cc1 +Cc1csc2nc(-c3ccncc3)nc(N3CCCNCC3)c12 +CN(C(=O)OC(C)(C)C)c1ccc(-c2nc3ccccc3s2)cc1 +CC(C)CN(c1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1 +CSc1ccc2c(c1)C(=O)N(CC1(C#Cc3cccnc3)NC(=O)NC1=O)C2 +CC(C)(NC(=O)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1)c1ccccc1 +CNCc1cc(C(=O)N(C)C)ccc1Oc1ccc(Cl)cc1C +CC(C)Nc1cc(-c2[nH]c(SC(C)C)nc2-c2ccc(F)cc2)ccn1 +CCCN(CCC)CCNC(=O)c1cc2c(-c3ccc(Cl)cc3)nn(C)c2s1 +Nc1nccn2c(C3CCC3)nc(-c3ccc(C(=O)c4ccccc4)c(Cl)c3)c12 +CCOC(=O)CC1CC(n2cc(-c3ccccc3)c3c(N)ncnc32)CN1C(=O)OC(C)(C)C +O=C(O)Cc1ccccc1OCCC1Oc2ccccc2N(CCCCCCCF)C1=O +NS(=O)(=O)c1ccc(-n2cc(-c3nc4ccccc4[nH]3)c(-c3ccc(Cl)cc3)n2)cc1 +Cc1ccccc1N1CCN(CC(O)COc2cccc(C(=O)c3ccccc3)c2)CC1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccnc2)CC1 +O=[N+]([O-])c1ccc(CSc2ncnc3c2ncn3Cc2cccc(F)c2)cc1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccncc1 +C=CCC1Oc2cccc(Cl)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +COc1cccc2oc3ccc(C#Cc4ccccn4)cc3c(=O)c12 +CC(C)C(=O)OCC1(CO)CC(=Cc2ccc(F)c(Br)c2)C(=O)O1 +COc1nc(-c2cccnc2)nc2c1CN(C(=O)Nc1ccccc1)CC2 +CC1(C)OC2=C(C(=O)C(=O)c3ccccc32)C1n1cc(CNC2=CC(=O)c3ccccc3C2=O)nn1 +CCCCC(NC(C)=O)C1CC(C(=O)O)CC1NC(=N)N +O=C(c1ccc(F)cc1F)N1CCN(c2ccc(OC3CCN(C4CCC4)CC3)cc2)C(=O)C1 +Cc1c(C(=O)Nc2cccc(C(F)(F)F)c2)cc(-c2ccccc2)n1CCCN(C)C(=O)C(C)C +CN(C)C(=O)CCCCCc1ccc(C(=O)Nc2sc(-c3ccncc3)nc2C(N)=O)cc1 +Cc1nc(NC(=O)NC(C)c2ccccc2)cc2[nH]nc(OCCO)c12 +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)Nc3ccc(F)cc3)sc2c1 +CNC(=O)c1cc(CSc2ncccc2C(=O)Nc2cc(C)cc(C)c2)ccn1 +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)C5CNC(=O)C5)C4)c3C2)cc1C(F)(F)F +CCCCc1nn(CCCOC(=O)N(C)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCCCN(CC(O)C(Cc1ccccc1)NC(=O)OCCNC(=O)C(F)(F)F)S(=O)(=O)c1ccc2ncsc2c1 +O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCN(c2cccc3nc(CO)cn23)CC1 +CCCCCCCCCCCCOC1(c2ccc(Br)cc2)SC=C(C)n2c1noc2=O +c1ccc(-c2ncc(-c3cnc(-c4ccccn4)[nH]3)cn2)cc1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1ccc(Cl)cc1 +CC(O)C1C(CO)CC2CCCCC2C1C=Cc1ccc(-c2cccc(C(F)(F)F)c2)cn1 +COc1ccc(COc2nc(N3CC4CC4C3)ncc2C(=O)NCc2cnc(C)cn2)cc1Cl +C=C(c1ccccc1)c1ccc2c(C=Cc3ccccc3)n[nH]c2c1 +Cn1cc(-c2cc3c(-c4cc(N5CCCC(F)(F)C5)ncn4)n[nH]c3cc2F)cn1 +CCC(NC(=O)c1cc(C(=O)N2CCC(F)C2)n2c1CCCC2)c1ccccc1 +CC(CCCCn1cnc2c1NC=NCC2O)(C(=O)O)C(=O)OCc1ccccc1 +CCCS(=O)(=O)c1cccc(C#Cc2cc(F)ccc2OCC(=O)O)c1 +C=C(C)c1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +Cn1ccc(Cc2cnc(SCCCCCCCCc3ccccc3)nc2O)cc1=O +COC(=O)C12CC1CCN(C(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)C1=CCCNC1)C(C)C)C2 +CN1CCN(C2Cc3ccccc3Sc3ccc(-c4ccn(C)n4)cc32)CC1 +CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)N(CCCN(C)C)c3nc4cc(OC)ccc4s3)cc2)CC1 +O=C(O)CC1CCCc2c1n(Cc1cccc(OCCCCCc3cccnc3)c1)c1ccc(F)cc21 +COc1cccc(C#CCN(c2cc(OC)cc(OC)c2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Nc1nc2[nH]c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c2c(=O)[nH]1 +CCOC(=O)c1c(NC(=O)Cn2cnc([N+](=O)[O-])n2)sc2c1CCC(C)C2 +NC(=O)c1ccc2c(c1)CCCN2c1cc(F)c(CNC2Cc3ccccc3C2)c(F)c1 +CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1ccc(-c2ccccc2)cc1 +Cn1c(=O)c(Cl)c(Nc2ccc(Br)cc2F)c2c(=O)n(CC(O)CO)cnc21 +O=C(c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1ccc(CN2CCOCC2)cc1)C1CC1 +COc1cccc2c(=O)[nH]c(-c3ccc(Br)cc3)nc12 +COc1cc(N=[N+]=[N-])c(I)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 +O=S(=O)(c1ccc(F)cc1)N(Cc1ccccc1OC1CCOCC1)c1cc(F)ccc1F +Cc1ncoc1-c1nnc(SCCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)n1C +O=C(O)Cc1cc(Br)c(N(Cc2ccc(Oc3ccccc3Br)cc2)Cc2cc(F)cc(F)c2)c(Br)c1 +Cc1ccccc1OCC(=O)NN=Cc1ccc([N+](=O)[O-])o1 +COc1n[nH]c2ncc(NC(=O)c3c(F)ccc(NS(=O)(=O)Cc4ccccc4)c3F)cc12 +CCCCCNC(=O)NCCCCC=CCCCCCCC(=O)NS(=O)(=O)c1ccccc1 +CC12CCC3C(CCC4CCOCCC43C)C1CC=C2c1cccnc1 +O=C(c1csc(-c2cccc(Cl)c2Cl)n1)N1CCCOCC1 +Cc1ccc(C(=O)NCC(N)=O)cc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12 +CC(C)Oc1ccc2c(c1)C(c1ccc(F)cc1)=C(C(=O)O)C(c1ccc3c(c1)OCO3)O2 +CCc1nn(Cc2ccc(S(=O)(=O)Nc3ccc(C)c(Cl)c3)cc2)c(CC)c1CC(=O)O +CC(C(=O)Nc1ccc(C(=O)O)cc1)n1ccc(-c2cc(Cl)ccc2Cl)cc1=O +COc1cc(CCN2CCN(CCCc3ccccc3)CC2)ccc1OCCF +CN(C)C(=O)CN1CCc2ccc(Nc3nc4c(-c5cccc6c5OC(F)(F)O6)cccn4n3)cc2CC1 +NC1=NC(c2cccc(NC(=O)c3ccc(Cl)cn3)c2)(C(F)F)COC1 +COc1ccc(N2C(=O)Nc3cc(OC)c(OC)cc3C2c2ccc(Cl)cc2)cc1 +O=C(Nc1ccccc1-c1ccc(Cl)cc1)c1cccnc1Cl +Cc1ccc(-c2nc(N)c3cc(Cc4ccccc4Cl)sc3n2)o1 +CC(C)=C1CC(C)(c2cc(NC(=O)c3cnc(C)cn3)ccc2F)N=C(N)S1 +COc1ccc(N(C(=O)c2ccco2)C(C(=O)NC2CCCC2)c2ccccc2F)c(OC)c1 +Cc1nccc(-c2ccc(Cl)c(C(=O)N(C)CCCN(C)C)c2)c1C#Cc1ccc(N)nc1 +CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(C=Cc3ccc(C#N)cc3)ccc21 +COc1cc(C(=O)c2sc(-c3ccccc3Cl)cc2N)cc(OC)c1OC +COc1ccc(N=Nc2sc(N3Nc4onc(-c5ccccc5)c4C3c3ccc(Cl)cc3)nc2C)cc1 +O=C(O)CCc1ccccc1CCC1C2CCC(O2)C1c1nc(C(=O)NCCCCC2CCCCC2)co1 +CN(c1cc(CCC2CC2)cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CC2)c1)S(C)(=O)=O +CCn1nnc(C2OC(n3cnc4c(Nc5ccc(Cl)cc5F)nc(Cl)nc43)C(O)C2O)n1 +CN(C)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +CC(C(=O)NC1CC(=O)OC1O)N1CCCCC(NC(=O)OCc2ccccc2)C1=O +COc1cccc(N2CCN(CCCCOc3ccc4c(C)cc(=O)oc4c3)CC2)c1 +CCCCCCCCCCCCCC(=O)OC1CCC(NC(=O)C(OC)C(O)C(O)C(O)C=CC(C)C)C(=O)N(C)C1 +CN(C)Cc1nc2c(sc3ccc(C#CCCCCN4CCCCC4)cc32)c(=O)[nH]1 +CCCCCCCCCCCCCCCCNC(=O)C(N)COP(=O)(O)O +O=c1ccc2ncc(F)c3c2n1CC3(O)CC12CCC(NCC=Cc3ccccc3)(CC1)CO2 +CCCCCCCCN(C)C(S)=NCc1ccc(O)c(OC)c1 +O=C(c1ccc(F)cc1C(F)(F)F)N(c1ccc(O)cc1)c1ccc(OCCN2CCCCC2)cc1 +CN(c1ncc(F)cn1)C1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 +COC(C)COc1cc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)ccn1 +Cc1nc(O)c2c(Sc3ccc(S(=O)(=O)c4ccccc4)cc3)c(C)ccc2n1 +O=C(NCc1ccncc1)c1cc(F)cc(C(F)(F)F)c1 +O=C(NO)C1CC2(CN1S(=O)(=O)c1ccccc1)OCCO2 +CCCCc1nc2cc(S(=O)(=O)NC(C)C)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(Nc1cccc(O)c1)c1ccc(OCCCN2CCCC2)cc1OCc1cscn1 +CN1CCCCC1C(=O)N1CCC(n2cnc3cnc4[nH]ccc4c32)CC1 +C(=Cc1ccccc1)CN1CCN(CC2ON=C3c4ccccc4NCC32)CC1 +CCCCCc1ccc(S(=O)(=O)NCCc2c[nH]c3ccccc23)cc1 +O=c1[nH]c(N2CCC(N3CC=C(c4ccccc4)CC3)C2)nc2ccccc12 +Clc1ccccc1-c1csc2nc(N3C4CCC3COC4)nc(N3C4CCC3COC4)c12 +CCC(=O)n1c2ccccc2c2cc(CN3CCC4(C=Cc5ccccc54)CC3)ccc21 +Cc1cc(-c2c(O)nc3cc(Cl)c(C(=O)Nc4cnsn4)cc3c2OCCC2CCO2)cc(C)c1C +Clc1ccc2c(NCCCCCCCNc3c4c(nc5cc(Cl)ccc35)CCCC4)c3c(nc2c1)CCCC3 +COc1cc(CNC(=O)c2cc(-c3ccc(C(C)(C)C)cc3)n(C)n2)ccc1OC(C)(C)C(=O)O 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+Cc1cc(CC(NC(=O)N2CCC(c3cccc(Br)c3)CC2)C(=O)N2CCC(N3CCCCC3)CC2)cc2cn[nH]c12 +N#Cc1cc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)oc3c2)ccc1F +COc1cc(-c2ccc(NC(C)c3ccc(F)cc3)nc2)ccc1-c1cc(C)ns1 +Oc1cccc(-c2cc(Nc3cnc4ccccc4c3)nc(N3CCOCC3)n2)c1 +Cn1c(=O)[nH]c2cc(-c3nn(C(C)(C)C)c(N)c3C(N)=O)ccc21 +Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)C(F)(F)F)cn3)n(-c3ncccn3)c2c1 +OCC1OC(n2cnc3c(NCc4cccnc4)ncnc32)C(O)C1O +COc1ccccc1NC(=O)N1CCC(c2nc(-c3cc4ccccc4cn3)no2)CC1 +CC(NC(=O)c1ccc(-c2nc(C3=CCCCC3)cnc2N)cc1F)c1cc(F)cc(S(C)(=O)=O)c1 +O=C(O)C=NOC(c1ccc(OCc2ccccn2)cc1)C1CCCCC1 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3c(F)c(F)c(F)cc3[nH]2)o1 +COC(=O)C(C)CN(c1ccc2c(c1)nc(C)n2Cc1ccc2ccc(C(=N)N)cc2c1)C1CCN(C(C)=N)CC1 +C=CCN(CC#N)C(=O)C(N)C12CC3CC(CC(C3)C1)C2 +CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C#N)cccc32)c1 +CN(C)Cc1c(C(=O)NCCCCN2CCN(c3cc(C(F)(F)F)nc(C(C)(C)C)n3)CC2)[nH]c2ccccc12 +CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cc(F)cc(Cl)c1 +O=C(O)c1cc(-c2ccc(Br)cc2)nc2ccc(OC(F)(F)F)cc12 +COc1ccc(C2CN(C)Cc3cc(OCCCNC4CC4)ccc32)cc1 +Cc1cc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)cc(C2CCCC2)n1 +O=C(NC1CCc2ccccc21)c1cncc(N2CC3CNCC3C2)c1 +CC1(C)OB(c2ccc(C(=O)Nc3nnc(S(N)(=O)=O)s3)cc2)OC1(C)C +COc1cc(C(=O)c2n[nH]c3c(C#CCO)c(OC)ccc23)cc(OC)c1OC +Cc1nc2cc(Cl)c(-c3ccc(C(=O)Nc4ccccc4F)s3)cc2o1 +COc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc(Cl)cc2)ccc1CCCN1C(=O)CCC1=O +O=C(NCC(C(=O)O)S(=O)(=O)c1c(Cl)cccc1Cl)C1=NOC2(CCC(CNc3ncc[nH]3)CC2)C1 +c1ccc(CN2CCN(c3cccc4ccoc34)CC2)cc1 +CCC=CCC=CCC=CCCCCCCCC(=O)OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(O)c(O)c1 +Cn1c2c(c3ccccc31)CN(CCCOc1ccc3ccccc3c1)CC2 +COc1ccc(-c2nc3cc(-c4csc(C(=O)NCCC(C)C)c4)cnc3[nH]2)cc1 +Cn1cncc1CN1CC(N(Cc2ccsc2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21 +CCCOc1cccc(-c2ccc(CCCC(P(=O)(O)O)S(=O)(=O)O)cc2)c1 +O=C(NCCCCc1ccccc1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 +O=C(Nc1ccc(C2CCCCC2)cc1)c1nnc(Nc2ccccc2F)o1 +NS(=O)(=O)OCC1OC(n2cnc3c(CN4Cc5ccccc5C4)ncnc32)C(O)C1O +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)C5CCOCC5)C4)c3C2)cc1Cl +COc1cccc(C(=O)NC(c2ccccc2OC)c2cc(Cl)c3cccnc3c2O)c1 +Cc1nc(N2CCN(C(=O)C3CCC3)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +O=C(CN1CCC(O)CC1)C(O)(c1ccccc1)C1CCC1 +O=C(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1[nH]nc2ccccc12 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NS(C)(=O)=O +CCc1cc(F)c(Cc2cnc(Nc3ccc(Oc4cccnc4)c(Cl)c3)o2)c(F)c1 +Cc1ccc(Cc2ccc3c(c2)CC(=O)N(O)C3=O)cc1 +Cc1ccc(Cn2nc(C(=O)NN3CCCCC3)c3c2-c2c(C)csc2C3)cc1 +Cc1cn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-n3cnc(-c4ccccc4)c3)c12 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccc(OC(F)(F)F)cc4)nc23)N1 +COc1cc(C)cc2cc(-c3c(COCCO)c(CN4CCNC(=O)C4)n4ncnc(N)c34)sc12 +Cc1c(C=C2C(=O)NN=C2c2cnccn2)[nH]c2ccccc12 +O=c1ccn(COCCCS(=O)(=O)NCc2cccc(OCC3CC3)c2)c(=O)[nH]1 +CC(C)(CO)NCc1noc(C(CCCC2CCCCC2)CC(=O)NO)n1 +CCNC(=O)c1ccc(-c2cc3nnn(C4CCN(c5ncc(CC)cn5)CC4)c3cn2)cc1Cl +Cn1cc(C=C2Oc3cc(O)cc(O)c3C2=O)c2c(-c3ccccc3)ccnc21 +Cc1cccc2cc(C(C)Nc3nc(F)nc4[nH]cnc34)n(-c3ccccc3)c(=O)c12 +N#Cc1c2n(c3c(N4CCN(CCc5cccc([N+](=O)[O-])c5)CC4)ncnc13)CCCC2 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(C3CCOCOC3)c2)CCCCC1 +CCCN(CCc1ccccc1)C(=O)C1OC(C(O)O)=CC(N)C1NC(C)=O +CC(C)(C)C#Cc1cnc2c(c1)C1(COC(N)=N1)c1cc(-c3cccnc3F)ccc1O2 +O=C1NCc2nc(Sc3ccc(F)cc3)ccc2N1c1c(F)cccc1Cl +O=C(O)c1cc2cc(OCc3c(Cl)cccc3Cl)ccc2n1Cc1cc2c(cc1Cl)OCO2 +C[S+]([O-])c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1 +COCCOCCOCCOCCOCCOCCOCCOCCOC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CCC2)C1O5 +CCCCCN(CCCCC)c1nc2nn(C)cc2c2nc(-c3ccco3)nn12 +CCCn1c(=O)c2[nH]c(-c3cc(C)n(CC(=O)Nc4ccc(Cl)cc4)n3)nc2n(CCC)c1=O +Cc1ncccc1NC(=NC#N)NC(NC(=O)CCCCc1ccccc1)C(C)(C)C +CCN(CC)CCNC(=O)C1c2ccc(OCc3ccccc3)cc2CCN1C(=O)OC(C)(C)C +CC(C)(C)CN(C(=O)CCC(=O)N1CCC(C(=O)O)CC1)c1ccc(Cl)cc1C(O)c1cccc(F)c1Cl +COc1cc(C=Cc2nc(-c3ccccc3)c[nH]2)ccc1-n1cnc(C)c1 +CCN(C)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3C)cc1 +Nc1ncc(F)n2c(C3CCC4CCC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c12 +COc1cc2c(Oc3ccc(NC(=O)c4cn(-c5ccccc5Cl)nn4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 +Cc1ccc(C2CC3CCC(C2c2nnc(-c4ccccc4)s2)N3C)cc1 +O=C1OC2(CCC(O)CC2)CCN1C(c1ccc(Br)cc1)C1CC1 +N#Cc1nccc(N2CCC(S(=O)(=O)c3ccccc3C(F)(F)F)C2)n1 +CN(C)CCNC(=O)c1c(C(N)=O)nc2n1CCOc1cc(F)c(C#CC(C)(C)O)cc1-2 +N#Cc1cnc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)cc1OCC1CCCO1 +COc1cc(C=Cc2csc3ccccc23)cc(OC)c1OC +CC(C)CC(O)C(O)C(CC1CCCCC1)NC(=O)C(C)OC(Cc1ccccc1)C(=O)N1CCCCC1 +CC(C)CN(Cc1ccc(N2CCC(S(C)(=O)=O)C2)cc1)S(=O)(=O)Cc1ccccc1 +OC1(c2ccc(Cl)cc2)CCN(Cc2coc3ccccc23)CC1 +CCCN(CCC)C1CCn2c(C=C(C#N)C#N)ccc2C1 +Fc1ccccc1-c1ccc2oc(N3CCN4CCC3CC4)nc2n1 +CCCc1nc(C(=O)NCCN2CCN(c3cccc(Cl)c3Cl)CC2)cn1-c1ccc(Cl)cc1 +CCc1cc(Cc2cnc(N)nc2N)cc2c1NC(C)(C)C=C2C +CCNc1ccc(C#Cc2c(CC)ncnc2-c2ccc(C(=O)N3CCC4(CC3)COC4)c(F)c2)cn1 +N#CC(NC(Cc1ccccc1)C(N)=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1 +Nc1nccn2c(C3CCC4CCC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)on4)cc3)c12 +COC(=O)C(NC(=O)c1ccc(Sc2c(C)ccc3nc(N)nc(O)c23)cc1)c1cccc(O)c1 +FC(F)(F)c1ccc2nc(C3CCN(Cc4ccc(-c5nc6ccnn6cc5-c5ccccc5)cc4)CC3)[nH]c2c1 +CN(C)c1nc(NCCCNCCCCCCCCCCCCNCCCNc2nc(N(C)C)nc(N(C)C)n2)nc(N(C)C)n1 +O=C1Cc2ccccc2C2(CCN(C(=O)Nc3cnc(-c4ccccc4)cn3)CC2)N1 +COc1cc(F)ccc1-c1nc(Nc2cc(Cl)cc(CS(C)(=N)=O)c2)ncc1F +Nc1ccc(-c2nc3ccc(-c4nc5ccc(F)cc5s4)cc3s2)cc1 +Cc1cc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)on1 +CCc1c(Cl)nc(NCc2ccc3c(n2)NCCC3)c(=O)n1CC(=O)NC(CC(=O)O)c1cccc(F)c1 +CC(C)C(O)(c1ccc(C#N)c(Cl)c1Cl)C(F)(F)F +O=c1cc(N2CC3CC2CO3)nc2n1CCC(C(F)(F)F)N2CC1CCOCC1 +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2cccc(F)c2)c(C)c1 +COc1ccc(NC(=O)NCc2cnc3scc(-c4ccc(Br)cc4)n23)cc1 +CCCCCCc1nc2cc(C=CC(=O)NO)ccc2n1C1CCNC1 +O=c1[nH]nc(Cc2c(Cl)cccc2Cl)c2ccccc12 +COc1ccc2c(c1)C(=O)C(=Cc1ccc(CN(C)Cc3ccccc3)cc1)C2 +CN(C)C(=O)Oc1ccc(CC(Nc2ncncc2-c2ccncc2)C(=O)O)cc1 +CC(C)c1cccn2c(C3(c4ccc(Cl)cc4)CC3)nnc12 +COC(=O)C=Cc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1 +COc1cccc2c(C(=O)c3cccc4ccccc34)c(C)n(CCN3CCOCC3)c12 +COc1ccccc1C=c1c(=O)[nH]c(=Cc2cccc(Cl)c2Cl)c(=O)n1C +CC1(C)C(=O)C(c2ccc(S(C)(=O)=O)cc2)=C1c1ccccc1 +Nc1ccc(Cl)c[n+]1CCCCCCCCCCCC[n+]1cc(Cl)ccc1N +CCCN(c1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2C)ncn1)C1CCCCC1 +N#Cc1cccc(C(=O)NCCc2nc(-c3cccc(F)c3)cs2)c1 +COc1n[nH]c2ncc(NC(=O)c3cc(NC(=O)c4cccc(C(C)(C)C#N)c4)ccc3C)cc12 +COc1cc2c(-c3cc(OCC4CC4)cc(OCC4CC4)c3)nc(OCCCO)nc2cc1OCCO +CCCCC1NC(=O)CN(C)C(=O)C(CCC)NCCOc2ccccc2CCCNC1=O +Cc1ccc2c3c(ccc2n1)OCC(CN1CCN(c2ccc4ccccc4n2)CC1)O3 +CCCCC1(O)CCN(C(c2ccccc2)c2ccccc2)CC1 +Cc1cccc(C(=O)N2CCc3nc(C#Cc4ccccc4)sc3C2)c1 +C#CCCCn1ncc2c(N)c(C(=O)OCC3CC3)c(C)nc21 +CC(OC(=O)Nc1cnoc1-c1ccc(CSCC(=O)O)cc1)c1ccccc1Cl +COc1ccccc1Sc1ccc(-c2ccnc(N3CCC(CO)CC3)c2)cc1C(F)(F)F +NS(=O)(=O)c1ccccc1NS(=O)(=O)CCc1ccc(OC(F)(F)C(F)F)cc1 +CC1(C)CN(C(=O)c2ccc(Nc3nc(C4CC4)cn4c(-c5cn[nH]c5)cnc34)c(F)c2)CCN1 +O=C(Nc1ccc(Nc2ccc([N+](=O)[O-])c3ncnc(O)c23)cc1)Nc1ccc(C(F)(F)F)cc1Cl +COc1cc(Nc2ncnc(N3CCCc4cc(C)ccc43)n2)cc(OC)c1OC +Nc1c(N=Nc2ccc(-c3ccccc3OCCC[Na])nc2)cc(S(=O)(=O)O[Na])c2ccccc12 +COc1ccc2sc(C3CCN(CC(O)COc4cccc5[nH]ccc45)C(C)C3)cc2c1OC +Cc1cc(Cl)nc(C)c1C(=O)NCCC(C)N1CCC(N(Cc2ccsc2)C(=O)N(C)C)CC1 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+O=[N+]([O-])OCCNCCNc1c2c(nc3ccccc13)CCCC2 +COc1ccc(CCNCCCNC(=O)c2ccc([N+](=O)[O-])cc2)cc1OC +Cc1cccc(C)c1Nc1cccc(C(=O)NCCCCCCC(=O)NO)c1 +O=C(O)CCc1cccc(CC(=O)Nc2cc(-c3ccc(Cl)cc3)n[nH]2)c1 +OCC1OC(n2cnc3c(NCC4=CCCCc5ccccc54)ncnc32)C(O)C1O +COc1cc(-c2noc(NC(C)c3ccc(F)cc3)n2)ccc1-n1cnc(C)c1 +COC(=O)NC(=O)C1CCCN1C(=O)C(CC1CCCC1)CN(O)C=O +O=C(NCCCc1ccccc1)Nc1cccc(CCNCC(O)c2ccc(O)c3[nH]c(=O)ccc23)c1 +Cc1cc2c(OCC(O)CN3CCC(c4cc5c(C)cccc5s4)CC3C)cccc2[nH]1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C(C)(F)F)nc1C +O=C(Cc1ccccc1)N1Cc2c(nc3ccccc3c2O)C1c1ccc2c(c1)OCO2 +N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)F)c3)C3=C2C(=O)CC3)cc1 +O=C(NCC1CCCNC1)c1ccnc2nc(Cc3cccs3)[nH]c12 +CC(=O)c1cccc(C#CC2(O)CCC3(C)C(CCC4C3CCC3(C)C(C(C)=O)CCC43)C2)c1 +CCCCNS(=O)(=O)n1nc(C(N)=O)c2c1-c1c[nH]nc1CC2 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCCCc1cn(CCCO)nn1 +CNC(=O)c1cccc(-c2n[nH]c3ccnc(OC4CCOCC4)c23)c1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(CCc1ccccc1)C(=O)COc1ccccc1 +Cn1nnc(-c2ccc3c(c2)c(C2CCN(CCN4CCNC4=O)CC2)cn3-c2ccc(F)cc2)n1 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+O=C(Cc1ccccc1)NC1CC(C(=O)O)Nc2cc(I)cc(Cl)c21 +O=C(COC(=O)c1ccccc1Br)Nc1nnc(-c2ccccc2)o1 +O=C(O)COCC1CCC(COC(=O)N(c2ccc(F)cc2)c2ccc(Cl)cc2)CC1 +COc1ccc(F)c(CCNC(=S)Nc2ccc(Br)cn2)c1F +O=C(CCCCCCOc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1)NO +Cc1nc(-c2nc[nH]n2)ccc1-c1cnc2c(n1)N(CCC1CCOCC1)C(=O)CN2 +CC(CCn1cc(-c2ccc(Cl)cc2F)nn1)(C(=O)NO)S(C)(=O)=O +CN1C2CCC1CC(OC(=O)N(Cc1ccccc1)c1ccsc1)C2 +O=C(c1ccoc1)N(c1ncccn1)C1CCN(CCc2ccccc2)CC1 +CCCCN(CCCC)CCCNc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCO +O=C(Cc1cn2cc(Cl)ccc2n1)N1CCC2(CC1)CN(Cc1ccc(-c3ncccn3)cc1)C2 +COC(=O)Nc1nc2cc([Se]c3c[nH]c4ccc(C#N)cc34)ccc2[nH]1 +O=C1C(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1c1ccc2c(c1)CCNC2 +CCSC(=S)SCC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 +CCNC(=O)Nc1nc2nc(NCCCN3CCN(C)CC3)ncc2cc1-c1c(Cl)cccc1Cl +COc1ccc(S(=O)(=O)Oc2c3ccccc3cc3ccccc23)cc1 +CC(C)c1ccc2occ(C=C3SC(=O)N(CC(=O)O)C3=O)c(=O)c2c1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(N2CCOCC2)nc1OCCOC(=O)Nc1ccccn1 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+COc1cc2c(cc1OCCCN1CCCCC1)Cc1c-2n[nH]c1-c1ccc(-c2ccc(O)cc2)cc1 +Cc1cn(C2COC(COC(=O)C(N)CCC(=O)O)O2)c(=O)[nH]c1=O +N=C(N)NCCCC1C(=O)N(C(=O)c2ccc(-c3ccccc3)cc2)C1C(=O)O +COc1cc(N2CCN(C3CCOCC3)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1Cc1cccc(Cl)c1)CC2 +O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 +COc1ccc2ccc(=O)oc2c1C1=NN(S(=O)(=O)c2ccc(Cl)cc2)C(c2cccs2)C1 +CC(Cc1ccccc1)Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O +CC1CCC(Cn2c(N3C(C)CCC3C)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +COc1cc(C(=O)C2COC(c3ccccc3)=N2)cc(OC)c1OC +CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1ccc2[nH]ccc2c1 +CC#CCOc1ccc(S(=O)(=O)N2Cc3ccc(CN4CCNCC4)cc3N(C(C)=O)CC2C(=O)NO)cc1 +CC(C)(NS(=O)(=O)c1cccc(OCC2CC2)c1)c1ccc(Cn2ccc(=O)[nH]c2=O)cc1 +CNc1nc(Nc2c(C)cc(C)cc2C)nc(NC2CCN(Cc3ccc(S(N)(=O)=O)cc3)CC2)n1 +O=C(Nc1ccon1)NC12CC3CC(CC(C3)C1)C2 +O=C(NCC(F)(F)F)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 +CCc1cc2cc(C(=O)C3CCC(OC)CC3)ccc2nc1F +CC(c1ccc(F)cn1)c1c(CCN(C)C)sc2ccccc12 +Nc1c2c(nc3c1C(c1ccccc1)c1c(c4ccccc4oc1=O)O3)CCCC2 +O=C(CSc1nc2ccccc2c(=O)[nH]1)NC1CCC(c2nnc(-c3ccccc3)o2)CC1 +Oc1ccc(CC(O)CN2CCC(O)(Cc3ccccc3)CC2)cc1 +CCCCCCCCc1ccc(-c2cc3cn(C4CC(O)C(CO)O4)c(=O)nc3o2)cc1 +O=C(NCc1cccc(Br)c1F)C1CC(F)CN1C(=O)Cn1cc(C(=O)C(F)(F)F)c2ccccc21 +CCOc1cc(C=NNC(=O)C(OC)c2ccc3c(c2)OCCO3)cc(Br)c1OC +NS(=O)(=O)c1ccc(NC(=O)CSC(=O)N2CCCc3cccc(Cl)c32)c(Cl)c1 +O=C(COC(=O)Cn1cnc2ccccc21)Nc1cc2c(cc1Cl)C(=O)c1ccccc1C2=O +C=CC(=O)N1CCC(Oc2cc3c(Nc4ccc(Br)c(Cl)c4F)ncnc3cc2OC)C1 +COc1ccccc1CNC(=O)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O +O=c1[nH]ccc2c(Nc3c(Cl)cc(-c4ccn[nH]4)cc3Cl)nc3ccncc3c12 +COCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCC(N)=O)C(C)C)ccc1OC +CC(CCc1ccc(-c2ccc(C#N)cc2)cc1)(C(=O)NO)S(C)(=O)=O +CC(C)(C)NC(=O)NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Oc1ccc(I)cc1 +C=CCN1CC(C)N(C(c2ccccc2)c2ccccc2)CC1C +CNC(=O)c1cc2cc(OC)c(OC)cc2c2cnc3cc4c(cc3c12)OCO4 +N=C(N)c1ccc2[nH]c(Cc3nc4c(F)cc(F)cc4[nH]3)nc2c1 +O=C1OCc2cc(CCN3CCN(C(=O)Cc4ccc(-n5cnnn5)cc4)CC3)cc(F)c21 +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc(C#CCOC)cc2)cc1 +O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CN(C2CCC(C3CCCCO3)CC2)C1 +CN1CCN(C(=O)Cn2cc(C(=O)N3CCC4(CC3)OCc3ccccc34)c3ccc(Cl)cc32)CC1 +O=C(Nc1ccc(CC(NS(=O)(=O)c2ccccc2)C(=O)O)cc1)c1cccc(NC2=NCCCN2)c1 +Cc1c(Cl)cccc1C(=O)N1CCCC(n2nnc(-c3ccccc3)n2)C1 +N#Cc1cnc(N)nc1N1CCCC1c1nc2cccc(C(F)(F)F)c2c(=O)n1-c1ccccc1 +Cn1cccc1Cc1ncc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)n1 +CCCCCCCOc1ccc(OC)c(Cc2cnc(N)nc2N)c1 +CN1C2CCC1C(C(O)C(F)(F)F)C(c1ccc(Cl)cc1)C2 +O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CN(C2CCC(c3ccccc3O)CC2)C1 +COc1ccc(-c2nnnn2-c2cc(OC)c(OC)c(OC)c2)cc1Cl +CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(Cc2ccccc2)n1 +CC(C)CNCc1cccc(C(=O)c2csc(S(N)(=O)=O)c2)c1 +N#Cc1ccc(NC(=S)NC(=N)Cc2ccc(Cl)cc2Cl)cc1 +COc1ccc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)cc1 +CCNC(=O)Nc1ccc(-c2cc3ccc(OC(=O)N(CC)CC)cc3oc2=O)cc1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1CC=CCC1C(=O)O +Cc1cc(O)cc(C)c1CC(N)C(=O)NC(CCCNC(=N)N)C(=O)NC1Cc2ccccc2CN(CCC(N)=O)C1=O +CCn1c(NC(C)C)nc2c(C3CCNCC3)csc2c1=O +Clc1cccc(-c2cc(NCc3ccncc3)n3nccc3n2)c1Cl +CCCCC1N(CC2CCCCC2)C(=O)OC12CCN(C1CCN(C(=O)c3c(C)cccc3C)CC1)CC2 +CCCCCCCCCCCCCCCCCCOCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(-c2nnc[nH]2)cc1 +N#CC(Cc1ccc(-c2ccc3c(c2)CC(=O)N3)cc1F)NC(=O)C1NC2CCC1C2 +CCCNC(=O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(OCc2ccncc2)cc1 +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)c5cncn5C)C4)c3C2)cc1C(F)(F)F +COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4nc(C)no4)cc3)C2C2CCCCC2)cc1 +Cn1cc(S(C)(=O)=O)nc1-c1c2c(=O)n(C)c(=O)n(CC3CC3)c2nn1Cc1ccnc2ccc(Cl)cc12 +CCCN(C)C1CCN(C(=O)c2ccc(Nc3nccc(-c4cnc(C)n4C(C)C)n3)cc2)C1 +COc1ccccc1N1CCN(CC(O)c2ccc(O)c(C(N)=O)c2)CC1 +COc1ccccc1N1CCN(CCCCn2cc(-c3ccc(Br)cc3)nn2)CC1 +O=C(Nc1ccc(Cl)c(S(=O)(=O)CC2CCNC2)c1O)Nc1cccc(F)c1Cl +COc1cccc(-c2cc3cnc(N)nc3nc2NC(=O)NC(C)(C)C)c1 +CCCCCCCCCCc1cc2cn(C3CC(O)C(CO)O3)c(=O)nc2s1 +COC1C(C)CC2(Cc3ccc(C#N)cc3C23N=C(N)N(CC2CCOCC2)C3=O)CC1C +NCc1ccc(CNC(=O)C(Cc2ccccc2)NC(=O)C(N)CC2CCCCC2)cc1 +CC(C)=CCn1c2c(ccc1=O)C(NCCc1ccc(O)cc1)CCC2 +N=C(N)NCCCC1NC(=O)C2CC(NC(=O)C(CC(=O)O)NC(=O)CNC1=O)C(O)C2O +NCCNc1cc(N2CCN(C(=O)Cc3ccccc3F)CC2)nc2ccccc12 +Cc1nc2cnc3ccc(C#CCNC(=O)c4c(C)n(C)n(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C(C)C +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(Cl)cn5)cc4=O)cc31)CCN1CCCCC21 +O=C(CN1CCCC1=O)NCc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +O=C(O)CC1CC(CNC(=O)CCNc2ccccn2)=CCc2ccccc21 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3cc(C4CC4)on3)n[nH]c2C1(C)C +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCC1OC(C)C(C)O1 +Cc1ccccc1N1CCN(C(=O)COc2ccc(Cl)c(N3CCN(C)CC3)c2)CC1 +CCCCCCC1(N2CCN(C(=O)C(Cc3ccc(Cl)cc3)NC(=O)CC3NCc4ccccc43)CC2)CCN(C)CC1 +Cn1cncc1CN1CC(N(CC2CCN(C(=O)c3ccccc3)CC2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21 +COc1ccc(C=NNC(=O)CSc2cc(C)nc3ccccc23)cc1OC +FC(F)(F)COc1ccc(-c2ccc3nnc(C(F)(F)F)n3c2)cc1 +Cc1nc(-c2cccc(CN3C(=O)CCCC3c3ccccc3-c3ccccc3)c2)cs1 +Nc1nc(CC(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cs1 +O=c1nc(OCC2COCCO2)cc2n1CCc1ccccc1-2 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1cccc(Sc2nc3ccccc3[nH]2)n1 +COCCN(C)c1ccc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)cn1 +Cc1nc2cnccc2n1CC1CCN(C(=O)C(C)c2ccc(N)cc2)CC1 +CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCCNC3)s2)o1 +Cc1cc(C(N)=O)nn1-c1cccc(-c2cccc(F)c2C(F)(F)F)c1 +Cn1cnc2cc(-c3ccc(F)nc3)nc(NC3CC3)c2c1=O +COc1cc(-c2nc(-c3cc(C)nc(C(F)F)c3)c3n2CC(CF)OCC3)ccc1OC(F)F +COc1ccc(Oc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1 +O=C(O)CCCCCOc1cc(-c2ccc(NC(=O)C(F)(F)F)cc2)cc(-c2ccccc2)n1 +COc1cc(OCc2csc(-c3ccno3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +COc1ccc(C2C(c3cc(OC)c(OC)c(OC)c3)C(C)=NN2C(C)=O)cc1O +COC(=O)c1ccc(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)cc1 +COc1ccc(C=CC(=O)c2ccccc2-c2ccc(F)cc2)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)C=Cc2ccc3c(c2)OCO3)CC1 +NC(Cc1nc2cc(Cl)c(Cl)cc2nc1CP(=O)(O)O)C(=O)O +O=S(=O)(NCC1CC1)c1ccc(NC2CN3CCC2CC3)cc1C(F)(F)F +O=C(Cc1cc[n+]([O-])cc1)N1CCN(C2c3ccc(Cl)cc3SCc3cccnc32)CC1 +CC(Nc1nc(Cl)cc(N2C(=O)OCC2C(C)O)n1)c1cnc(-c2ccccn2)s1 +COc1cc(C(=O)c2c[nH]c(-c3ccc(C(F)(F)F)cc3)n2)cc(OC)c1OC +CCc1nc(-c2cnc(C)cc2N(C)C)c(CC)nc1NC(CC)CC +O=C(O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)OCCCCC2CCCCC2)co1 +COc1cc(C(=O)NCCN(C)C)c(C)cc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2C(=O)N(C)C3)n1 +CC(C)C1C(=O)Nc2ccc(NC3CCCCCC3)cc2-c2nc3cc(C(=O)N4CCCN(C)CC4)ccc3n21 +Cn1cc(-c2cc(C(=O)N3CCS(=O)(=O)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +CCN1CCC(Nc2ccc(CN(CC(C)C)S(=O)(=O)Cc3ccccc3)cc2)C(F)(F)C1 +CNC(=O)c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nn1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1C(C)=O +CN(C)c1ccc(-c2nc3c(N4CCN(C(=O)Nc5ccccc5)CC4)c(Br)cnc3[nH]2)cc1 +O=C(Nc1ccc(Cl)cc1)C1CN(CCO)CC1C(=O)Nc1ccc(-n2ccccc2=O)cc1F +COc1ccc(Br)cc1CCc1c(Cl)cccc1-c1nc(C)c[nH]1 +Fc1cccc(F)c1Cc1cnc(Nc2ccc(COc3ccncc3)cc2)o1 +O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(-c3nc4cc5nc[nH]c5cc4nc3-c3ccccc3)cc2)CC1 +Clc1ccccc1Nc1nc2c(-c3nnc[nH]3)cccc2c2scnc12 +Cc1cc(C(=O)O)ccc1N1CC2(CCN(Cc3cn(C(C)(C)C)nc3-c3ccc(F)c(F)c3F)CC2)OC1=O +CC(C(=O)Nc1ccc(-c2ccccc2)cn1)n1nnc(-c2ccncc2)c1-c1ccccc1 +Cc1ccnc2c1C(=NN=C(N)N)CC(c1ccccc1Cl)C2 +Fc1cc(Nc2n[nH]c3cccnc23)cc(C(F)(F)F)c1 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+O=C1c2ccccc2S(=O)(=O)N1Cc1cccc([N+](=O)[O-])c1 +CS(=O)(=O)c1ccc(-n2cc(Cl)c(OC3CCN(c4ncc(C(F)(F)F)cn4)CC3)cc2=O)cc1 +COCCOCC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +COc1cc(C=Cc2nc3cc(Br)cnc3n(CC(=O)O)c2=O)ccc1O +CN1CCC(c2ccc(Cl)cc2)C(C(=O)OCCCCCOC(=O)C2CN(C)CCC2c2ccc(Cl)cc2)C1 +CCNC(=O)Nc1cn(-c2ncc(C)c(CCC(=O)O)n2)c2cc(-c3cccnc3)cnc12 +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)c3ccccc3c12 +NC(=O)c1ccc(NC2CNCCC2c2ccc(C(F)(F)F)c(F)c2)c2cncnc12 +CCCn1cc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cn1 +O=C(NS(=O)(=O)C1CC1)c1cc(C2CC2)c(OC2C3CC4CC2CC(Cl)(C4)C3)cc1F +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCCC1 +CC(C)(C)OC(=O)C(CCCCN)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1ccc(-c2ccccc2)cc1 +Cc1cc(C)cc(S(=O)(=O)NC(=O)Nc2ncc(Br)s2)c1 +O=c1n(-c2ccc(F)c(F)c2)ccc2nc(COc3ccccc3)cn12 +CC(=O)Nc1nc2ccc(-c3nn(Cc4cc5cccc(C)c5c(=O)n4C(C)C)c4ncnc(N)c34)cc2s1 +CC(C)Cc1cn(-c2nc(N)c3ncn(C4OC(COS(=O)(=O)NC(=O)c5ccccc5O)C(O)C4O)c3n2)nn1 +CCNC(=O)N1CCCN(c2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2NC(=O)c2ccsc2)CC1 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+O=C(O)Cc1ccc(OCC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)CC2CCOc4ccccc42)CC3)c1 +O=C(CCN1CC=C(c2ccc(F)cc2)CC1)c1ccc(F)cc1 +Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)C3CCCC3)CC2)n1 +c1ccc(-c2csc3ncnc(N4C5CCC4CC(COCCN4CCCC4)C5)c23)cc1 +O=C(O)CCCOc1ccc(-c2cc(OC3CC3)ccc2F)cc1 +CCCCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1CN1CCNCC1 +CC(NC(=O)CCN1CCC(c2ccccc2)CC1)c1ccc(Br)cc1 +Cc1ccc(-c2cc(C(=O)NC3CCCCC3)no2)cc1 +O=C(c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12)N1CCC(O)CC1 +NS(=O)(=O)c1ccc(C#CC2CCCCN2C(=O)COc2ccccc2)cc1 +CCn1c(C(=O)NCCN)ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 +CC(C)CC(O)C(O)C(CC1CCCCC1)NC(=O)C(C)OC(Cc1ccccc1)C(=O)N1CCOCC1 +O=C(NC1CCCCC1)C(c1cccnc1)N(C(=O)CCl)c1ccc(F)cc1 +CC(C=Cc1ccoc1-c1cc(C(C)C)cc(C(C)C)c1OCCCF)=CC(=O)O +O=C(c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1)N1CCCC1 +CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2C#N)cc1 +CCNCc1ccc(C(=O)Cn2ccc(OCc3ccc(Br)cn3)cc2=O)c(C)c1 +COc1ccc(C(=O)NC(c2ccccc2Cl)c2cc(Cl)c3cccnc3c2O)cc1 +NC(=O)C12CC3CC(C1)C(NC(=O)C1(NS(=O)(=O)c4cc(Cl)c(Cl)cc4F)CC1)C(C3)C2 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+N=C(N)N1CCCC(CC2C(=O)N(C(=O)N3CCN(C(=O)NCCCCc4ccccc4)CC3)C2C(=O)O)C1 +COc1cccc(OC)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCC(OC)CC1 +O=C1NCCc2c1ccc1[nH]cc(CCNCc3cn[nH]c3)c21 +COc1ccccc1C(=O)NC(=O)Nc1ccc(OCC(F)(F)F)c(C(F)(F)F)c1 +COCC(C)CN1C(c2c(F)cc(C=CC(=O)O)cc2F)c2ccc(O)cc2CC1(C)C +CC(=O)NP(=O)(O)OCC1OC(n2ccc(N)nc2=O)C(F)(F)C1O +CC(C)c1c(OCC(O)CN2CCN(c3ccnc4cc(Cl)ccc34)CC2)ccc2c1CCC1C(C)(C)CCCC21C +N#CCNC(=O)C1(NC(=O)c2ccc(-c3csc(N4CCC(N5CCOCC5)CC4)n3)cc2)CCCCC1 +O=C(NO)C1CC(c2ccc(-c3ccc(F)cc3)cc2)C(=O)N1 +CC(C)(NC(=O)c1ccc(C2CCCO2)c(-c2cccc(Cl)c2)n1)c1ncco1 +CNc1ccc(-c2ccc(C(=O)NCC(C)(C)C)cc2C(=O)O)c(C(=O)Nc2ccc3c(N)nccc3c2)n1 +CNC(=O)c1cc(CSc2nc(NCCO)c(C#N)c(-c3ccc(OCCO)nc3)c2C#N)ccn1 +COc1ccc2c(c1)c(CN1CCN(C)CC1)cn2S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(C)(=O)=O)cc2)n(-c2cccc(CN)c2)n1 +O=c1cc(-c2ccc(Cl)c(Cl)c2)oc2cc(O)ccc12 +Cn1nnc(-c2ccc(F)c3c(C(=O)C(=O)N4CCN(C(=O)c5ccccc5)CC4)c[nH]c23)n1 +Cc1c(Cc2c(F)cccc2F)nc(SCc2ccccc2)[nH]c1=O +Nc1ncc(-c2nc3ccncc3s2)c(NC2CC(CO)C(O)C2O)n1 +CNc1cnn(C2CC(C)(C)CC(C)(C)C2)c(=O)c1Cl +CN1CCc2ccc(Nc3nnc(-c4cncc(-c5cccnc5)c4)o3)cc2C1 +COC(=O)Nc1n[nH]c2cc(NC(=O)NC3CCOc4ccccc43)ncc12 +CN(CCCOc1ccc2ccc(=O)oc2c1)Cc1cccc(OC(=O)NCCCCCCCN2CCOCC2)c1 +Cc1cn(Cc2ccc(F)c(F)c2)c2c(-c3cc(NS(=O)(=O)c4ccc(F)c(F)c4)no3)cc(F)cc12 +Cc1ccccc1-c1ccc(Cc2nnn(C(=O)N(C)C)n2)cc1 +Cc1nc(NC(=O)c2cc(CNC(=O)C(C)C)cnc2C(F)F)[nH]c1-c1ccc(C(F)(F)F)cc1 +Nc1nc(N2CCNCC2)c2oc3c(Cl)cc(Cl)cc3c2n1 +Cc1cc(C(=O)Nc2ccc(C3CNCCO3)cc2F)cc(C#N)n1 +O=C(Nc1ccc(C(F)(F)F)c(Cl)c1)N1CCC(F)(c2ncc(C3=NOC(CO)C3)cc2Cl)CC1 +O=C1NCc2nc(Sc3ccccc3)ccc2N1c1c(Cl)cccc1Cl +O=C(Nc1ccc(Br)c(C(F)(F)F)c1)N1CC=C(c2ncc(C(O)CO)cc2Cl)CC1 +COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(C(C)N2CCCC2)cc1 +c1cc(NC2CCNCC2)c2nc(-c3nnc4ccccn34)ccc2c1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)NCC(c2ccc(Cl)cc2)N2CCOCC2)c1 +CCNC(=O)Nc1cccc(-c2n[nH]c(C3CCCCN3C(=O)COc3ccccc3)n2)c1 +O=C(Nc1cncc(Oc2cncnc2)c1)c1cccc(Br)c1 +CSc1cc(C)nc(SC)c1NC(=O)N(Cc1ccc(Oc2ccc(F)cc2)cc1)C(C)c1ccccc1 +COc1c(Cl)cc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1Cl +c1ccc(-c2nc(NCCN3CCOCC3)c3nc(NCCN4CCOCC4)c(N4CCCC4)nc3n2)cc1 +COc1ccc2nc3cccc(C(=O)NCCCN(C)CCCNC(=O)c4cccc5nc6ccc(OC)cc6nc45)c3nc2c1 +O=C(c1cccc(Oc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1)N1CCCCC1 +O=C(NCCCc1cccc2oc(CCCCc3ccccc3)cc12)C1CC1 +Cc1ccc(NC(=O)OCc2ccccc2)c(=O)n1CC(=O)NC(C(=O)C(F)(F)F)C(C)C +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2C#N)c(F)c1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCCC(F)(F)F)c12 +c1ccc(CC[n+]2cc(-c3ccccc3)n3c2CCC3)cc1 +Cc1cc(-c2ccc(NC(=O)C(C)c3cccc(-c4ccc(N(C)C)cc4)c3)cc2)ccn1 +NCCOc1c(-c2ccc(N3CCCC3)c(Br)c2)[nH]c(=O)c2cc(F)ccc12 +COc1ccc(C(=O)Nc2ccc(F)c(C34COC(CF)C3S(=O)(=O)C(C)(C)C(=N)N4)c2)nc1 +NCc1cc(CC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)ccn1 +Cc1c(C(=O)N2CC=C(c3ccc(F)cc3)CC2)sc2c1[nH]c(=O)c1ccccc12 +CCC(=C(c1ccccc1)c1ccc(O)cc1)c1ccc(O)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N4CCCC4C)n3)C2)cc1 +O=C1c2cccc3c(NCCO)ccc(c23)C(=O)N1c1cccc(Cl)c1 +COc1ccc(C=NNc2[nH]nc(C)c2C(=O)Nc2cccc(OC)c2)cc1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(-c4ccc(CN5CCCC5)cc4)c3c2)cc(Cl)c1O +CC(=O)N(CCCCNc1c2c(nc3ccccc13)CCCC2)CCCNc1c2c(nc3ccccc13)CCCC2 +O=C1N=C(NCc2ccccc2Cl)SC1=Cc1ccc2ncccc2c1 +Cc1ccc(NC(=O)c2cc(C(C)(C)C)on2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)n1 +CC(O)(CSc1ccccc1)C(=O)Nc1ccc2c(C(F)(F)F)cc(=O)oc2c1 +CCC(C)(Cc1ccc(OCCCOc2ccc3c(C(F)(F)F)cc(=O)oc3c2Cl)cc1)C(=O)O +c1cc2c3cnc(Nc4ccc(N5CCNCC5)nn4)nc3n(C3CCC3)c2cn1 +NC(=O)COc1ccc2c(c1)S(=O)(=O)C=C(c1c(O)c3cc(F)ccc3n(Cc3ccc(F)cc3)c1=O)N2 +Cc1nc(NC2CCCc3ccccc32)cc(-c2ccc(O)cc2)n1 +COC(=O)CCC(NC(=O)Nc1ccc(N(C)Cc2cnc3nc(N)nc(N)c3n2)cc1)C(=O)OC +CCc1c(Cc2c(Cl)cccc2Cl)c(=O)ccn1Cc1ccccc1 +Cc1ccc(S(=O)(=O)n2c(CN3C(=O)c4ccccc4C3=O)nc3cc(Cl)c(Cl)cc32)cc1 +O=C(Oc1cncc(Cl)c1)c1cccc([N+](=O)[O-])c1 +COc1ccc(-c2cn(C3CCC3)c3ncnc(N)c23)cc1 +COc1ccccc1N1CCN(CC=CCNC(=O)c2cc3cc(OCCOCCOCCF)ccc3[nH]2)CC1 +FC(F)(F)c1cc(COCC2(c3ccccc3)CCNCC2)cc(-c2ccc3ccccc3c2)c1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C(=O)NCCO +CCS(=O)(=O)c1ccc(-c2coc3ccc(-c4ccc(C)o4)cc23)cc1 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+CN(CCCN1c2ccccc2Oc2ccccc21)Cc1ccccc1 +CCCOc1cc(F)c(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 +COc1ncc(N2CCC(C(N)Cc3cc(F)ccc3F)CC2)cn1 +O=C(NC1COc2ncccc21)C1CCc2cc(Cl)cc(Cl)c21 +N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCC=CCOc3ccc(F)c(F)c3C(=O)N2)CC1 +Cc1nn(C)c(C)c1-c1cccc2c1CCC(N(C)C)C2 +O=C(O)c1ccc2c(c1)nc(NCCc1ccccc1)c1ccsc12 +CCOc1ccccc1N1CCN(CCCCCOc2cc(-c3ccccc3)ncn2)CC1 +O=C(Cc1ccc(-c2n[nH]c(=O)c3ccccc23)cc1)N1CCCc2ccccc21 +CC1CC2C3=CC=C(c4cncc(F)c4)C3(C)CCC2C2(C)CCNC(=O)C=C12 +NC(=S)Nc1cccc(OCCCCCCCCNC(=S)Nc2cccc(Br)c2)c1 +CC(NC1CCC(n2cc(C(N)=O)c(Nc3ccc(Cl)cc3)n2)C(C#N)C1)C1CC1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)c(NC(=O)CCC(=O)O)c2)nc2c(Cl)cc(Cl)cn12 +O=C(O)CC(NC(=O)c1ccc(Cl)cc1NC(=O)OCc1ccccc1)C(=O)CF +CC(C)(C)OC(=O)Nc1scnc1C(=O)Nc1nccs1 +CN(C)CCC1(C#N)CCN(c2c(Cl)cncc2-c2ccc3c(c2)CS(=O)(=O)N3C)CC1 +CC1(C)c2cc(C(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +Cc1cc(=O)[nH]c2[nH]nc(-c3cccc(C(F)(F)F)c3)c12 +COC(=O)CCCCCCC(=O)Nc1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)cn1 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+Cc1c(CN(C)C(=O)C=Cc2cnc3c(c2)CN(CCN2CCOCC2)C(=O)N3)sc2ccccc12 +CCN1c2cc(C)c(C)nc2N(C)C(=O)c2cccnc21 +CN=C1NC(=Cc2c[nH]c3c(Br)cccc23)C(=O)N1C +FC(F)(F)c1nc(Nc2c(Cl)cc(Cl)cc2Cl)sc1CN(CC1CC1)CC1CC1 +O=C(NC(c1ccc(Cl)c(Cl)c1)C1CCN(Cc2ccccc2)CC1)c1ccc2cnccc2c1 +CCC(CN1CCC(CNC(=O)c2ccc3cc(Cl)ccc3c2)NC(CNC(=N)N)C1=O)c1ccccc1 +O=C(O)C1COc2cc3nc(-c4cccs4)c(-c4cccs4)nc3cc2O1 +CCOC(=O)C1=C(C)NC2=C(C(=O)C(C(=O)OCC)C(c3cccc(OC)c3)C2)C1c1ccc(Br)cc1 +CCCCC(NC(=O)C(NC(=O)OCc1ccccc1)C(C)C)C(=O)C(=O)NOCc1ccccc1 +CC(C)(C)c1ccc(S(=O)(=O)N2C3CCC2CC(O)(O)C3)cc1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3sccc3-n3cccc3)CC2)nc1 +NC(=O)CN(c1ccccc1)c1cc(-c2ccc(Oc3ccc(F)cc3)cc2)cc(C(N)=O)n1 +Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 +CC(=O)Nc1nc2ccc(CCNC(=O)Nc3ccc(C)c(Cl)c3)cc2[nH]1 +CCCOC(=O)c1ccc(NC(=O)NC(Cc2ccc(O)cc2)C(=O)NC2CCN(Cc3ccc(O)cc3)C2)cc1 +O=C(NCc1cccc(C(F)(F)F)c1)c1cc(N2CCC(N3CCCC3)CC2)cc(C(F)(F)F)c1 +Cc1nnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4ccnc(N)c34)cc2)s1 +CCOC(=O)c1cnn(CC(C)O)c1NC(=O)Nc1cccc(F)c1 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+O=C(O)Cn1nnc(-c2cnc(N3CCC4(CCc5ccccc54)CC3)s2)n1 +O=c1[nH]c(-c2ccc(O)c(O)c2)nc2sc3c(c12)CCC3 +CCCCCCCCCCCCCCCCOP1(=O)OCCC(C(=O)OC)=C(C)O1 +CCOc1cc2c(cc1C(=O)NC)C(=N)N(CC(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C2 +O=S(=O)(c1ccc(Cl)cc1Cl)N1CCN(c2ncccc2C(F)(F)F)CC1 +CCc1nc2c(-c3ccc(Cl)cc3Cl)ccnc2n1C(CCOC)C1CCC1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(C(F)(F)F)cc1-c1ccn[nH]1 +N#CC(=CC1CC1)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cc(F)ccc3F)cc2)c2c(N)ncnc21 +CC1CN(c2scnc2-c2nc3c(F)cccc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21 +NS(=O)(=O)c1nnc(NC(=O)c2ccc([N+](=O)[O-])cc2)s1 +Cc1cc([N+](=O)[O-])cc(C)c1OCC1CCCN2CCCCC12 +O=C(c1ccccc1)N1CC2C(CNc3nc(-c4ccccn4)cs3)C2C1 +Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N2CCOCC2)cn1 +C=CCN1CCC23CC(=O)CCC2(OC)C1Cc1ccc(O)c(OC)c13 +CC(C)C1(C(=O)N2CCc3ccc(C(F)(F)F)cc3C2)CCC(NC2CCc3c(O)cccc32)C1 +CC(NC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(Cc2cccnc2)C1=O)c1ccccc1 +CN1Cc2c(C3=CC4COC(=O)N4CC3)[nH]c3nccc(c23)-c2cc(F)c(F)cc21 +O=C(CCCCCN1C(=O)c2ccc(NC(=O)c3ccc(F)cc3)cc2S1(=O)=O)NO +O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)c(CCCCN3CCOCC3)cc2n1CCO +CCCOc1cc2c(cc1OC)CC(=O)N(c1ccc(OC)cc1)C2c1ccc(Cl)cc1 +Cc1cc(Nc2nc(Nc3ccc(N4CCOCC4)cc3)ncc2Br)n(C)n1 +C=C(C)C1COc2c(C)cc3oc4c(CC(O)C(C)(C)O)ccc(O)c4c(=O)c3c2C1O +O=C1NCc2nc(Sc3cc(Cl)ccc3Cl)ccc2N1c1c(Cl)cccc1Cl +O=C(NC1CCCC1Nc1ccc(C(F)(F)F)cn1)c1c(F)cccc1-n1nccn1 +O=C(NC1CCCCC1)c1ccc(C#Cc2ccccc2)nc1 +COc1cnc(COc2ccc(F)cc2F)cc1-c1cc2c([nH]1)CCNC2=O +Cc1nc2c(N3CCN(C4CCC(c5c[nH]c6ccccc56)CC4)CC3)cccc2[nH]1 +Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)cc(-c3cccs3)oc2c1 +COc1ccc(-c2nonc2NC(=O)c2cccc(C)c2)cc1OC +Oc1ccc(C2Sc3cc(O)ccc3OC2c2ccc(OCCCN3CCCC3)cc2)cc1 +CCCC(CCC)n1cc2c3c(nc(C)cc31)N(c1ccc(C(F)(F)F)cc1C(F)(F)F)CC2 +CCCCC(=Cc1cc(OCc2cc3ccccc3s2)ccc1OCc1ccc(C(F)(F)F)cc1)C(=O)O +CCCCCCn1nc(C(=O)NN2CCCCC2)c(C)c1-c1ccccc1 +C=CC(=O)Nc1cccc(N2C(=O)N(C(C)C)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +CCc1coc2ccc(-c3cc(NC(C)c4cccc(OC)c4)nc(C)n3)cc12 +COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O +CCNCC1CC(NC(=O)c2cc(CC)nn2C)CN1C(=O)c1coc2ccccc12 +CC(Nc1ncnc2sc(-c3cccc(C(=O)O)c3)cc12)c1ccccc1 +Cc1ccc(C(=O)NCc2cccc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCC(F)C3)nc12 +Cc1ccc(-c2cnc(C(=O)N3CCCC3)o2)cc1S(N)(=O)=O +O=c1c(-c2cccc([N+](=O)[O-])c2)nc2ccccc2n1Cc1ccccc1 +O=C(Cc1ccccc1Nc1c(Cl)cccc1Cl)NCCOc1ccc2oc(=O)ccc2c1 +Cc1cc(NC(=O)CC(=O)O)c2c(c1Oc1ccc(O)c(CCc3ccccc3Cl)c1)CCC2 +CC(=NOC(=O)Nc1cccc2ccccc12)c1ccc(-c2ccccc2)cc1 +NC(=O)c1cc(-c2ccc(F)c(Cl)c2)cc2c1[nH]c1cc(C(=O)N3CCOCC3)ccc12 +COc1cc2c(cc1OCc1ccccn1)Cc1c(-c3ccc(C#N)nc3)n[nH]c1-2 +O=C1C2Cc3c([nH]c4ccccc34)C(c3ccccc3Br)N2C(=O)CN1Cc1ccccc1 +CN(CCCNC(=O)CNC(=O)Nc1ccc2ccn(-c3ccccc3Cl)c2c1)C1CCCN(c2ncnc3[nH]ccc23)C1 +CC(C)(O)c1cc2nc(NN=Cc3cn(Cc4cccc(C#N)c4)c4ccccc34)nc(N3CCOCC3)c2s1 +CN1C(=O)C(NC(=O)CCc2ccc(Cl)cc2Cl)N=C(c2ccc(C(N)=O)cc2)c2ccccc21 +CC1CC2CSC(N)=NC2(c2cc(CNCC(F)(F)F)c(F)cc2F)CO1 +O=C1CN(Cc2cn3cc(-c4cccc(O)c4)nc(N4CCOCC4)c3n2)CCN1 +COc1cc(C=c2sc3nc(-c4cccc(Cl)c4)cn3c2=O)cc(OC)c1O +COc1cccc(-c2cccc(C3(c4ccncc4)N=C(N)N4CC(F)(F)CN=C43)c2)c1F +CC(C)C1NC(=O)CC2C=CCCSSCC(NC1=O)C(=O)NCc1[nH]c3ccccc3c1CC(=O)O2 +CC1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)C1 +N#CC1(c2cc(-c3cnc(N)c(OC(F)F)c3)nc(N3CC4CC3C4)n2)CCC1 +Cn1c(-c2cccc(N3CCc4sc(C(=O)Nc5ccc(Br)cc5)cc4C3)c2)nc2ccccc21 +CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4ccsc34)cc2)CC1 +COCCCc1cc(CN(C(=O)C2CNCCC23OCc2cc(F)c(F)cc23)C2CC2)cc(OCCOC)c1 +COc1cccc(OC)c1Oc1nc(N)nc(Nc2ccc(C#N)cc2)n1 +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(NC2CCCCC2)C1 +COc1ccc(C2=NNC(=O)C2=NNc2ccccc2)cc1OC +COc1ccc(C(=O)Nc2ncc(Cc3ccc(F)c(C(F)(F)F)c3)s2)cc1OCCO +Cc1c(N2CC(C)(C)CCC2=O)nc2cc(F)cc(F)c2c1N1CC2(CCOCC2)c2ncc(N3CCOCC3)cc21 +CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1CC[N+](C)(C)C +COc1ccc(S(=O)(=O)n2cc(C3CCN(C)C3)c3ccccc32)cc1OC +O=C(c1cccc(Cl)c1)N1CCc2oc(-c3ccc(F)cn3)nc2C1 +Cc1cc(C2CCN(C(=O)C3CN(C(C)(C)C)CC3c3ccc(F)cc3F)CC2)n(-c2cccc(Cl)c2)n1 +O=C(Cc1cccc(C(F)F)c1Cl)NC1COc2ncccc21 +CC(C)(C)c1cc(NC(=O)Nc2cc(Cl)cc(Cl)c2)n(-c2ccc(Br)cc2)n1 +CCCc1sc(NN=Cc2ccccn2)nc1-c1ccc(Br)cc1 +CS(=O)(=O)c1ccc(-c2cnc3ccc(-c4cccc(C(F)(F)F)c4)nn23)cc1 +O=C(NC1C2CN(CCc3ccc4c(c3)OCO4)CC21)C(O)(c1ccccc1)C1CCCC1 +O=C(Nc1ccccc1)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2ccccc21 +CCOC(=O)C1=C(C)NC(OCC)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1 +O=C(c1ccc(Nc2nc3ccccc3n3nnnc23)cc1)N1CCN(c2ccccn2)CC1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1nc2ccccc2o1 +CC(C)Oc1cc(-c2cc(C3CCN(C4COC4)CC3)n(C3CCC(F)(F)C3)n2)cnc1N +Cc1nc(O)c2cc(CSC(=S)N3CCN(c4ccc(F)cc4)CC3)ccc2n1 +CN(C)CCNCC(=O)C(O)(c1ccccc1)C1CCCCC1 +Brc1cnc(Nc2ccc3[nH]cnc3c2)nc1NC1CCc2ccccc21 +CC(C)(C)C1(O)CCN(CC2c3ccccc3CCc3ccccc32)CC1 +CCN1CCC(NC(=O)c2ccc(Nc3ncc(C(F)(F)F)c(Oc4cccc5c4C(=O)N(C)C5)n3)c(OC)c2)CC1 +COc1cc2cc(C(=O)CCC3CC[N+](C)(Cc4ccccc4)CC3)sc2cc1OC +O=C1CCN1c1cc(Cc2n[nH]c(=O)c3cccnc23)ccc1F +O=C(OCC#CCOC1=C(OCC#CCOC(=O)c2ccccc2)C(=O)c2ncccc2C1=O)c1ccccc1 +CN(C)Cc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CNC(=O)C(Cc1ccccc1)NC(=O)C(CSC)NC(=O)CS +O=C(NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)NC1(C(=O)O)CC1 +COc1cccc(C(CN)Nc2ncnc3c(C(N)=O)cccc23)c1 +COc1ccc(-c2cc(F)ccc2N2CCN(CCCCCC(=O)NCc3ccc(C#N)cc3)CC2)cc1 +COc1cc(OC)cc(N(CC#CC2(O)CCNC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +COc1ccc(Nc2cccnc2-c2nc(C)nc(N)n2)cn1 +O=C(OCC#CCSc1nnc(-c2ccc3ccccc3c2)o1)c1ccc(F)cc1 +COc1cccc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)c1 +COc1cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)C=Cc3ccc(F)cc3)cc2)ncn1 +[C-]#[N+]c1ccc(Cn2c(CC3(C(=O)O)CCCC3)nc3cc(OCc4ccc5ccccc5n4)ccc32)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4csc(CN5CCCC5)c4)nc23)N1 +CNC(=O)C1OC(n2cnc3c(NC4CC(C)(C)NC(C)(C)C4)ncnc32)C(O)C1O +CNC(=O)NCC1CC1c1cccc2c1OC(C(C)C)N2 +OC(CN1CCN(c2ccccc2)CC1)Cn1nc(-c2ccccc2)c2c1CCNC2 +COc1ccc(Nc2nc(-c3cccc(C(=O)Nc4ccc(CC(=O)O)cc4)c3)cn3ccnc23)cc1OC +CCOC(=O)C=CC(=O)N(CC(N)=O)NC(=O)C1CCCN1C(=O)C(NC(C)=O)=C(C)C +O=C1C(=Cc2cccc3cnccc23)CCC1=Cc1cccc2cnccc12 +CCN1CCN(S(=O)(=O)c2cnc(OCCOC)c(-c3nc4c5n(nc4c(=O)[nH]3)CCCC5)c2)CC1 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+CCN1CCC(Oc2ccc(C(=O)Nc3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)nc2)CC1 +O=C1c2ccccc2-c2c1c(NCCN1CCCCC1)nc1ccc(Cl)cc21 +CCOc1cc(C(=O)O)nc2ccc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)cc12 +CCC(C)N(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(S(=O)(=O)c2ccc3[nH]ncc3c2)CC1 +CCC(=O)Nc1cccc(C(=O)Nc2cccc(Nc3cc(-c4c(-c5ccc(F)cc5)nc(SC)n4C)ccn3)c2)c1 +CCCCCCCCc1ccnc(N2CCc3cc(S(=O)(=O)Nc4ccccc4)ccc32)n1 +CC(C)(C)Cc1ccc(S(=O)(=O)N2CCC(NCC(O)COc3cccc4[nH]c5ccccc5c34)CC2)cc1 +Cc1cc(-c2ccncc2)cc2[nH]c(C3COc4ccccc4O3)nc12 +CC(C)(C)Nc1nc2cc(Cl)c(Cl)cc2nc1S(C)(=O)=O +COC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C2c3cc(F)cc(F)c3CC2O)C1 +C[N+](C)([O-])c1ccnc2sc3c(=O)n(C4CCCCCC4)cnc3c12 +CN(C)CCCN1CC(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +NC1CC2(CCN(C(=O)c3cc(NC(=O)c4cc(-c5ncccc5F)c(Cl)cc4Cl)n(-c4ccccc4)n3)CC2)C1 +COc1ccc(NC=CC(=O)c2cc(OC)c(OC)c(OC)c2)cc1Cl +CN(C)c1ccc(C=NNc2ncnc3scc(-c4ccc([N+](=O)[O-])cc4)c23)cc1 +CS(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CCC4(CC3)OCCO4)cc2C(N)=O)cc1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(N2CCN(c3cccc(F)c3)CC2)cc1F +CNc1ncnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +CN1C(=O)CN=C(c2ccccc2)c2cc(C#N)ccc21 +C#CCOc1ccc2c(C3=C(c4cn(C)c5ccc(Br)cc45)C(=O)NC3=O)coc2c1 +CCCN(CCC)c1c(OC)nn2c(-c3c(OC)cc(COC)cc3OC)csc12 +O=C(c1ccc(O)nc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +CCCCCCCCCCCCCc1ccc(NC(=O)Nc2c(C(C)C)cccc2C(C)C)cc1 +Cc1cc(-c2cc(C)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncco5)ccc43)cc2F)ccc1Cl +CCN(C(=O)c1cc(C)ccc1-n1nccn1)C(C)Cn1nnc(-c2ccc(F)cn2)n1 +O=C1COc2c(Cl)cc(Cl)cc2N1Cc1nnc(CCc2ccc(Cl)cc2)n1CCC(F)(F)F +CCc1ncnc(-c2ccc(C(=O)N3CCN(O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +Cc1cccc(C(=O)O)c1Oc1nc(Oc2cccc(-c3cccc(CN)c3)c2)c(F)cc1F +O=c1oc2cc(OCCN3CCN(Cc4ccccc4)CC3)ccc2c2ccccc12 +CN1c2ccc(F)cc2C(=O)N(C2CCN(CCCn3ccnc3-c3ccccc3)CC2)C1c1ccccc1F +O=C(CNC(=O)Nc1ccc2cnccc2c1)NC1CCCC1 +Nc1nc(N)c2nc(CNc3ccc(Cl)cc3Cl)ccc2n1 +COc1cc(C=CC(O)=CC(=O)C=Cc2ccc(OCc3ccccc3)cc2)ccc1O +CCc1c(C(=O)c2cc(C)cc(C)c2)n(CCC2C=CCC2)c(=O)[nH]c1=O +O=C(Cn1nnc(-c2ccncc2)c1-c1ccccc1)Nc1ccc(-c2ccoc2)cn1 +CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CC(=O)NC(C)c1ccc(OC2CN(c3cccc(C(F)(F)F)c3)C2)cc1 +c1ccc(-c2csc3nc(OC4CC5CC4CN5)nc(N4C5CCC4COC5)c23)cc1 +CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)Cc2cnccn2)ccc1Oc1ccc(F)cc1F +O=C(OC1CC2(N3CCCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2)c1ccccc1 +CC(C)Oc1ccc(C=NNC(=O)C(CSCc2ccccc2)NC(=O)c2ccc([N+](=O)[O-])cc2)cc1 +CC#CC(C)(O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 +O=C(Nc1nc2c(s1)CC(N1CCOCC1)CC2)c1cccc(CNC(=O)c2csc(-c3cccnc3)n2)c1 +CCOC(=O)C1C(c2ccc(-c3cccn3CC)cc2)CC2CCC1N2C +O=C1NCc2cc(F)c(OCCCN3CCN(c4cccc5ccccc45)CC3)cc21 +Cn1c(=O)c(-c2c(Cl)ccc(O)c2Cl)cc2cnc(Nc3ccccc3)nc21 +Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccccn4)cc3=O)cn12 +C=CC(=O)N1CC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccc(Cl)cc5)cc4)nn32)C1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1CCOc2ccc(OC(C)C)cc21 +Cc1cc(=NCCC2CCN(Cc3ccccc3)CC2)[nH]nc1-c1ccccc1 +CC12Cc3cnn(-c4ccccn4)c3C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(=O)CSc1nc2ccccc2s1 +COc1cnc(C(=O)Nc2ccc3c(c2)C2(COC(N)=N2)C2(CC2)C(C)(C)O3)cn1 +CCCc1cc(OC)nc2nc(C(=O)c3ccccc3)cn12 +CC#CCOc1ccc(S(=O)(=O)NC(Cc2c(C)n(Cc3cccc(F)c3)c3ccc(OC)cc23)C(=O)O)cc1 +N=C(NCc1ccccc1)c1ccc(OC(F)(F)F)cc1 +O=C(NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1)c1ccc(F)cc1 +CCOc1ccc(-c2nc(C)sc2-c2cc(OC)c(OC)c(OC)c2)cc1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC(C)O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +CC(NC(C)(CCc1ccccc1)C(=O)O)C(=O)N1CCCC1C(=O)O +Cc1nn(CCC(F)(F)CO)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2 +CC1(C)CC(O)(COc2ccc(C3CCC4(CC3)OOC3(O4)C4CC5CC(C4)CC3C5)cc2)CC(C)(C)N1 +Cc1cc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5ccc(Cn6cccn6)cc5)nc34)CC2)no1 +N#Cc1cc(-c2ccnc(Nc3ncc(C4CCNCC4)cn3)c2)ccc1OC1CCOCC1 +O=C(NC(Cc1ccccc1)C(O)CC1(Cc2ccccc2)N=CC(C2CNC(=O)c3ccccc32)=C1O)OC1CCOC1 +Cc1ccc[n+](C(C)C(=O)c2ccc(-c3ccccc3)cc2)c1 +COC(=O)C1(Cc2cccc(F)c2)NCc2cnc3c(-c4ccc(C(F)(F)F)cc4)c(C(N)=O)nn3c21 +COc1cccc2c(=O)[nH]c(-c3ccc(C)cc3)cc12 +NS(=O)(=O)c1ccc(NC(=O)CCCCN2CCOCC2)cc1 +COc1ccc(-c2ccc[nH]c2=O)cc1C(C)(C)C +CCC1CN(C(=O)Nc2ccccc2)c2ccc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)cc2O1 +CS(=O)(=O)N1CC=C(c2cc3cc(C4CCN(c5ccc(C(F)(F)F)cn5)CC4)oc3cn2)CC1 +COc1ccc2cc(-c3cc(C(F)(F)F)nn3C(C)c3ccc(C(=O)NCCC(=O)O)cc3)ccc2c1 +CCCCN1CCN(c2ccc(S(=O)(=O)Oc3cc(OC)c(OC)c(OC)c3)cc2)C1=O +N=C(N)c1ccc(O)c(CN2CCC(NS(=O)(=O)c3cc4c(Cl)nccc4s3)C2=O)c1 +N#Cc1nc(NC2CCCCC2)c(N)c(N2CCOCC2)n1 +CC(C)(C)CCN1C(=O)C(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)SC1c1c(F)cccc1F +CC(C)CC(NC(=O)CCN(C)C)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C2CSCC2c2ccc(Cl)cc2)CC1 +CCCCCc1ccc(-c2nnc(-c3ccccc3C(F)(F)F)n2C)cc1 +COc1ccc(C(=O)n2c(C)c(Cc3cccc(OC(C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc32)cc1 +CC(O)C(NC(=O)Nc1cc2[nH]nc(OCCOC(F)F)c2cn1)c1ccc(F)cc1 +Nc1c(-c2nc3cc(N4CCOCC4)ccc3[nH]2)c(O)nc2ccncc12 +Cn1nccc1-c1cc(C(F)(F)F)ncc1Oc1ccc(S(=O)(=O)Nc2cscn2)cc1C#N +Cc1c(N(CCC2CC2)S(=O)(=O)c2ccc(N3CCOCC3)cc2)sc2ccccc12 +Cc1n[nH]c2nc(-c3ccccc3)c(C#N)c(-c3ccccc3)c12 +CC(C)S(=O)(=O)N1CC2CC=C(c3ccc(CCN4CCCC4)cc3)C2C1 +CCCOC(=O)N1CCc2c(nc(CC(C)(C)C)n2CC2CC2)C1 +COCCCOc1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)cc2ccoc12 +NS(=O)(=O)c1ccc(OCCCN2CCC(C(O)(c3cccc(F)c3)c3nccs3)CC2)cc1 +CCc1nc2c(C)ccnc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +N=c1oc2ccccc2cc1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CN(c1nc2ccc(Cl)cc2s1)C1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 +Cc1cc(CCC(=O)O)ccc1OCc1cccc(Oc2ccccc2)c1 +CC#CCC(C)C(O)C=CC1CC(F)(F)C(=O)N1CCCCCCC(=O)O +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4cnco4)o3)cc2Cl)CS1(=O)=O +CC#CCC(O)(c1ccc(N2CCN(S(=O)(=O)c3ccc(N)nc3)CC2C#CC)cc1)C(F)(F)F +Cc1cccc(S(=O)(=O)n2cc(NC(=O)c3nccs3)cn2)c1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(-c3ccccc3)n[nH]c2C1 +CCCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(Cl)cc3Cl)ccnc21 +Cc1ccc(-c2ccc(C=C3SC(=S)N(C)C3=O)o2)cc1Cl +CCC(C)C(S)C(=O)NC(C(=O)N1CCCC1C(=O)O)C(C)C +CCCCOc1ccccc1N1CCN(CCCN2C(=O)C3CCCN3C2=O)CC1 +COc1ccc(C=Cc2nnc(NC(=O)c3ccccc3OC)s2)cc1OC +NC(=O)Nc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(F)cc2)ccn1 +COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccc(C#N)cc2)CC1 +CC12CCC3C(CC(O)C45CC4CCC35C)C1=CC=C2c1cccnc1 +O=S(=O)(c1cc(Cl)c2oc3c(c2c1)CNCC3)n1ccc2ccccc21 +NC(=O)c1cc(C(O)CO)nc(-c2ccc(Oc3cc(Cl)ccc3F)cc2)n1 +Cn1c(Nc2ccc(C(=O)NCCCCCCC(=O)NO)cc2)nc2ccccc21 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CC3CC1CC(CC(=O)O)(C3)C2 +O=c1c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc2n1NC1CCCCC1 +O=C(NC1CCN(Cc2ccc3c(c2)OCCO3)CC1)c1cc(=O)c2ccc(F)cc2o1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCN2CCOCC2)CCCC1)c1ccc2ccccc2c1 +Cc1cc(CN(CC2CCCC2)C(CC(=O)O)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CN(C)C1=O +CS(=O)(=O)c1ccc(-c2sc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1 +CN(C)CCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1 +CCCN(CCC)C(=O)c1c(C)c2c(C(=O)OCC)ncn2c2ccccc12 +Cc1ccc(C(=O)NC2CC2)cc1Oc1nncc2c1cnn2-c1c(F)cccc1F +CN(C)CC(=O)Nc1ccc2c(-c3c(-c4ccccn4)nn4c3CCC4)ccnc2c1 +CC(C)(Cc1cccc(CC(=O)NCc2ccc(Cl)c(Cl)c2)c1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1 +CCN1C(=O)c2cccc3c(S(=O)(=O)Nc4cccc(C(C)=O)c4)ccc1c23 +C=CC(=O)Nc1cccc(CSc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2Cl)c1 +COCc1csc(-c2nc(C(C)(C)C)nc3nc(N)c(C#N)c(N)c23)n1 +OC1(C(F)(F)F)CCc2c1[nH]c1cc(Cl)c(Cl)cc21 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1ccnc(N2CCOCC2)c1 +COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cncnc4N)ccc23)cc1 +CCc1c(-c2nnc(C(C)(C)C)o2)nc(-c2ccccc2Cl)n1-c1ccc(Br)cc1 +Cc1cccc(Nc2ccccc2C(=O)NCCC(=O)NCCCCNc2c3c(nc4ccccc24)CCCC3)c1C +O=C(CCCCCCCCn1cc(-c2cccnc2)nn1)NCC(c1ccccc1)c1ccccc1 +COc1ccc(NS(=O)(=O)c2ccc(Br)c(C)c2)cc1N1CC(C)NC(C)C1 +O=C(Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1)N1CCN(c2ccc(Cl)cc2)CC1 +Cn1c(=O)c2c(cc(OCc3ccc(Cl)c(C(F)(F)F)c3)n2C)n(C)c1=O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CN4CCC(N5CCCCC5)CC4)c(O)ccc3nc2-1 +CCC(C)(C)C1CCC(N2CCC(N3C(=O)Cc4ccccc43)CC2)CC1 +CC(=O)c1ccc(-c2cccc(-n3cc(C(=O)NC(C)C)c(=O)c4cccnc43)c2)cc1 +COc1cc(OC)cc(-c2c[nH]c3ncc(-c4cccc(N)c4)cc23)c1 +Cc1ccc(-c2c(=O)n(CCCCN3CC=C(c4c[nH]c5ccc(Br)cc45)CC3)c(=O)n3ccccc23)cc1 +COc1ncc(Nc2ncc(C(C)(C)N3CCOCC3)cc2-c2nc(C)nc(N)n2)cc1F +COc1ccc2ccc3oc(CCNC(=O)C4CC4)cc3c2c1 +CNC(=O)CN1CCC2=C(C1)c1c(O)cc(C(C)CCCc3ccc(F)cc3)cc1OC2(C)C +N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)cc3O)o2)nc1 +CCc1ccnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +O=S(=O)(c1ccc2cc[nH]c2c1)N1CCCC1CCN1CCC(c2cc3ccccc3[nH]2)CC1 +O=C(O)CCCOc1ccc(-c2ccc(-c3ncc(C(F)(F)F)[nH]3)cn2)cc1 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1cnc(N(C)Cc2cccc(C(=O)O)c2)c(Cl)c1 +CCCN(c1cc(C(=O)Nc2ncc(CC(=O)O)s2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC +CCCn1c(=O)c2nc(C34CC5CC(CC3C5)C4)[nH]c2n(CCC)c1=O +O=c1cc(-c2ccccc2)oc(O)c1C(SC1CCCCC1)c1ccccc1 +O=C(CCS(=O)(=O)Cc1ccccc1)Nc1nnc(C(F)(F)F)s1 +COc1ccc(N2CCN(CC(O)c3ccc(O)c(C(N)=O)c3)CC2)cc1 +CCCn1c(=O)c2[nH]c(-c3cn[nH]c3)nc2n(CC)c1=O +CN(C)C1CCN(c2cc(-c3c(N)nn4cccnc34)ncn2)C1 +Cc1cccc(NC(=O)C=Cc2cccc([N+](=O)[O-])c2)c1 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)N1CC=C(c2ncc(C(O)CO)cc2Cl)CC1 +CN(C)c1nc(C(F)(F)F)nc2c1ncn2Cc1ccc(Cl)cc1[N+](=O)[O-] +CC1C2CCC3C4CC=C5CC(N(C)C(=O)c6ccccc6)CCC5(C)C4CCC32CN1C +CCN(CC)CCNc1n[n+]([O-])c2ccc(Cl)cc2[n+]1[O-] +COc1ccccc1-c1csc(Nc2ccc3c(c2)OCO3)n1 +Cc1cccc2c1cc(C(=O)NCc1ccc([N+](C)(C)C)cc1)n2Cc1cccc(C(=N)N)c1 +CC1CC(NC(=O)CCc2nc(-c3ccc(O)cn3)no2)=C(C(=O)O)CC1c1cccc(F)c1 +Cc1cc(-c2nc(-c3cnc(OCC4COC(=O)N4)c(C)n3)no2)cc(NC(C)C)n1 +CC(C)(C)OC(=O)N1CCC(c2cc3cc(-c4ccc(NS(C)(=O)=O)cc4)ncc3o2)CC1 +Cn1c(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccco1 +COC(=O)C1=C(Nc2cc[nH]n2)OC(=Cc2c[nH]c3ncccc23)C1=O +CCOC(=O)c1ccc2nc(-c3cccnc3)c3c(c2c1)NCCC3 +Nc1n[nH]c2cc(NC(=O)NCc3ccccc3OC(F)F)ncc12 +N#CCNC(=O)c1ccc(-c2ccnc(Nc3ccc(N4CCSCC4)cc3)n2)cc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1CC(N)CCO1 +CNC(=O)C1CCCCN(C)C(=O)COC(C(=O)NO)C(CC(C)C)C(=O)N1 +CC(C)Oc1ccc(OCC2c3ccc(OC(C)C)cc3CCN2C(=S)c2cccc(Cl)c2)cc1 +O=CC(Cc1ccccc1)NC(=O)C1CCCN1S(=O)(=O)c1ccccc1[N+](=O)[O-] +COc1cc(CNC(=S)NC(CCc2ccc(C(C)(C)C)cc2)COC(=O)C(C)(C)C)cc(Br)c1O +COc1cc(NC(C)CCCNCc2ccc(COC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)c2ncccc2c1 +COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3C)c2cc1OC +O=C(O)c1cnn(-c2cnc(NC(=O)C(OC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)c1 +O=C(c1ccco1)N1CCN(c2c3c(nc4cc(-c5ccc(F)cc5)nn24)CCC3)CC1 +COc1c(C)n(OC)c2c(c1=O)C(CCCCCc1ccccc1)CCC2 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2NS(=O)(=O)c1cccc(F)c1 +O=CC(Cc1c[nH]c2ccccc12)NC(=O)CCc1ccccc1 +Nc1nnc(-c2ccc3[nH]cc(-c4cncc(N5CCCCC5)n4)c3c2)s1 +Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)NC2(C(=O)O)CCCCCC2)c(C)c1 +COCCOC1CN(C(=O)c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)C1 +Cc1cc(-c2ccccc2)cc(-c2ccccc2)[n+]1CCc1ccc(S(N)(=O)=O)cc1 +CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCCN2C3=O)CC1 +COc1ccc(-c2[nH]c3ncc(Cl)cc3c2-c2cccc(CNC(C)=O)c2)cc1 +O=C(Nc1cc(C(=O)N2CCN(C3CC3)C(=O)C2)nn1-c1ccccc1)c1cc(-c2ccccn2)c(F)cc1Cl +Cc1cc(C)c(-c2nc3c([nH]2)CCN(C)CC3)cc1C(=O)N1CC(c2ccc(C#N)cc2)C1 +CN(C)S(=O)(=O)NC(=O)c1ccc(OCC23CC4CC(CC(C4)C2)C3)c(C2CC2)c1 +COC(=O)C(C)c1ccc(C)c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)nc12 +OC(CNCCC(Oc1ccc(C(F)(F)F)cc1)c1ccccc1)COc1ccccc1C1CCCC1 +NS(=O)(=O)c1nc2ccc(OS(=O)(=O)C(F)(F)F)cc2s1 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)NC(CCNC(=O)OCc1ccccc1)C(=O)O +CCCCCC(=O)Nc1ccc2c(c1)CC(CO)NC(=O)C(C(C)C)N2C +c1ccc(-c2c(-c3ccc4[nH]ncc4c3)nc3ncccn23)cc1 +Cc1[nH]cnc1Cc1nc(-c2cccc3cccnc23)cs1 +O=C(C1CCOCC1)N1CCC(Nc2ncnc3c2CN(c2cncc(C(F)(F)F)c2)CC3)C1 +CCOc1ccc(CC(NC(=O)c2ccccc2)C(=O)N(C)C(Cc2ccccc2)C(=O)NCc2ccc(CN)cc2)cc1 +Cn1cc2c(n1)Nc1ccc(F)cc1N=C2N1CCN(CC2CC2)CC1 +Cc1c(C(C)C)c(=O)on1C(=O)N(C)c1ccccn1 +O=C(O)C(CCN1CCC(O)(c2ccc(Cl)c(C(F)(F)F)c2)CC1)(c1ccccc1)c1ccccc1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(nc(C(F)(F)F)nc2-c2ccn[nH]2)C1 +CN1CC(=O)N(CC(=O)NCc2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)C1=O +O=C1C=C(c2ccc(F)cc2)OC12CCN(CCc1ccccc1)CC2 +CCOC(=O)c1c(-c2cccc(-c3ccccc3)c2)[nH]c2cc(OC)c(OC)cc2c1=O +CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]c(=NC(=O)c1cocn1)n2CCC(N)=O +N=C(N)Nc1ccc(C(=O)Oc2ccccc2C(N)=O)cc1 +Nc1ncc(-c2cc(C3C4COCC43)n(C3CCCC3)n2)cc1Cl +C[S+]([O-])c1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc1 +CCN1CCC(N(CC)c2cc(OC)cc3c(=O)cc(C(=O)Nc4ccc(N5CCOCC5)cc4)[nH]c23)C1 +O=C1C(O)=CC(=Nc2ccc(Cc3ccncc3)cc2)c2ccccc21 +COc1ccc(CNC(=O)c2cc(-c3cncc(C)c3)ncc2-c2ccccc2F)nc1OC +COc1cc2c(cc1OC)-c1cc3ccc(OC)c(OC)c3c(=O)n1CC2 +CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccc(Cl)cc1 +CC1CCN(c2ncnc3[nH]cc(-c4cccc(C#N)c4)c23)CC1 +CN1CCC2(C)c3cc(OC(=O)Nc4ccccc4Br)ccc3N(C)C12 +COc1ccccc1-c1cc(OC)c(-n2c(=O)ccc3cc(S(=O)(=O)Nc4ccon4)ccc32)cc1F +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)cc1F)Nc1cc(C(F)(F)F)ccc1F +CCCOCCn1c(=O)c(NCC(=O)NC)nc2ncc(-c3ccc(OC)nc3)cc21 +N=C(CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O)c1ccccc1N +CN(C)CCN1C(=O)c2cccc3c2c(cc2[nH]c(-c4ccccn4)nc23)C1=O +Cn1cc2c3cc(Br)ccc3nc-2c2cc(Cl)cc(F)c21 +Brc1cccc(Nc2ncnc3cnc(NCCN4CCOCC4)cc23)c1 +O=C(O)c1ccc2c(c1)C(SCCN1CCN(c3ccc(F)cc3)CC1)c1ccccc1CO2 +Cc1c(C(=O)NCCN2CCOCC2)[nH]c2cnnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12 +O=C(O)C(=O)C=C(O)c1cn(Cc2ccccc2)c(=O)[nH]c1=O +CCCn1c(=O)[nH]c2[nH]c(-c3ccc(S(=O)(=O)O)cc3)nc2c1=O +CCN(c1cc(-c2ccc(C)nc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +Clc1cccc2[nH]cc(CCCN3CCN(c4cccc5c4OCCO5)CC3)c12 +CC(=O)ON=C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc21 +CC(=O)N1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +CC=CC=CC=CC[N+](C)(C)CCCCCCCCCCCCC +Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnccc1N1CCC(F)CC1 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+Cc1nc2sc(C(=O)NCc3cccnc3)c(N)c2c(C)c1Cl +CCNc1nc2cc(OC)c(Cl)cc2nc1NCCCN1CCCC1 +CCc1ccccc1NC(=O)CCN1CCN2Cc3ccccc3CC2C1 +O=c1c(-c2ccc(F)cc2)c2ccccn2c(=O)n1CCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1 +O=C(c1ccco1)N1CCN2C(=O)c3ccncc3C12c1ccc(Cl)cc1 +COc1cccc(S(=O)(=O)N(Cc2ccc(N3CCN(C(C)=O)CC3)cc2F)C2CCC2)c1 +O=C(NO)c1cnc(NC2(c3cc(F)cc(F)c3)CC2)nc1 +Cc1cc(C)cc(N(C(=O)CSc2nnc(-c3ccoc3C)n2Cc2ccco2)c2ccccn2)c1 +O=C(O)C1CCCN(CCCC=Cc2ccccc2-c2ccc(F)cc2F)C1 +CNC(=O)CC1COc2cc(Br)ccc2N1C(=O)c1ccc2c(c1)NC(=O)CO2 +CNc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(C)c2)ncn1 +CCn1c(C(=O)NC(C)C(=O)O)ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1 +CN(Cc1nc2c(N3CCOCC3)nc(-c3ccncc3)nc2n1C)c1ncc(C(=O)NO)cn1 +O=C1NC(CS)C(=O)N(CC2CCCCC2)C1CC1CCCCC1 +COC(=O)c1c[nH]c2cc(CN3CCN(Cc4ccc(OC)cc4)CC3)ccc2c1=O +CC(C)C1C(=O)N(S(C)(=O)=O)C2CCN(C(=O)C3CN(CC(C)(C)C)C3)C12 +O=C1c2ccccc2CCCN1CCN1CCC(n2ccc3ccccc32)CC1 +COc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Nc2ccc(C)cc2)CC1 +CC(C)(C)S(=O)(=O)N(CCCCCCN1CC(O)C(O)C(O)C1CO)C1CCCCC1 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+c1ccc2c(CC(COc3cncc(-c4cc5ccncc5s4)c3)Nc3cc4ccncc4s3)c[nH]c2c1 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(Cc1cccc(C(F)(F)F)c1S)CC(C)C +CCc1c(C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)oc2ccccc2c1=O +CS(=O)(=O)c1ccc(C(=O)N2CCN(c3ccc(OC4CCN(C5CCC5)CC4)cc3)C(=O)C2)cc1 +CCC1Cc2n[nH]cc2CN1S(=O)(=O)c1ccc(Cl)cc1 +O=c1ccoc2ccc(OCc3ccc(C(F)(F)F)cc3)cc12 +NS(=O)(=O)c1cccc(-c2n[nH]c3ccc(NS(=O)(=O)c4cccs4)cc23)c1 +COc1ccc(N2CCN(C(=O)CN(C)C)CC2)cc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +COc1ccc2nc3cc(Cl)ccc3c(NCCCSCC3CCCN4CCCCC34)c2c1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1cccc(CN2CCCCC2)c1Cl +CC1(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2F)COC(C)(C(F)(F)F)C(N)=N1 +Cc1ccc(NC(=O)c2cccc3ccccc23)c(=O)n1CC(=O)NC(CC(=O)O)C(=O)COc1ccccc1 +CCOc1cccc(F)c1C1CC(C)C(=O)N1Cc1cccc(-c2ncc(C)s2)c1 +COc1cc(OC)cc(N(Cc2ccc(Cl)s2)c2ccc3ncc(-c4cnn(CCO)c4)nc3c2)c1 +CCCCc1nn(Cc2cccc(C(=O)OC)c2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(c1ccccc1)N1CCC(CCCCn2cc(-c3ccccc3)nn2)CC1 +CCCCOC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ccc2ccc3c(C#N)cc(C(=O)c4ccccc4)n3c2c1 +CCCCc1nnc(OCCc2ccccc2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +Cc1nn(-c2ccccc2)c(C)c1C=NNC(=O)c1cc(-c2ccccc2)[nH]n1 +C1=C(c2ccc3ccccc3c2)CCN(CCCCc2ccncc2)C1 +Oc1[nH]c(Nc2cccc(CC(F)(F)F)c2)nc2ncnc1-2 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1Nc1ccc2nc[nH]c2c1 +COc1cccc(OC)c1NC(=O)c1ccc(-c2cc(Cl)ccc2Cl)o1 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC1C(=O)N2CCOC12 +N#CC(C(=O)Nc1ccc(C(F)(F)F)cn1)=C(O)C1CC1 +Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(C(F)(F)F)n2)c(=O)c2ccccc21 +Cc1ccc(Nc2nnc(SCC3CCCCC3)[nH]2)cc1 +COC(=O)CNC(=O)c1ccc(-n2ncc3c(N)ncnc32)cc1 +Cc1c(Oc2ccc(S(C)(=O)=O)cc2F)ncnc1N1C2CC3CC1CC(C2)N3C(=O)OC1(C)CC1 +CC1CCc2cc(-c3ccc(-n4ccnc4)nn3)ccc2N1C(=O)c1ccc(O)cc1O +CN(C(=O)C(CC(=O)O)NC(=O)CCCCOc1ccc(C(=N)N)cc1)C(Cc1ccc(O)cc1)C(=O)O +O=S(=O)(c1ccc2c(c1)CCNCC2)N1CC(Oc2cccc(Cl)c2)C1 +C=C(c1ccc(S(=O)(=O)c2ccc(OC)cc2)cc1)C1CCN(C2CCN(S(=O)(=O)Cc3ccccc3)CC2)CC1 +COc1cc(CNC2COC(C(c3ccccc3)c3ccccc3)CC2O)ccc1O +CN1CCN(c2ccc(Nc3nc4c(-c5ccc(N(C)S(C)(=O)=O)cc5)cccn4n3)cc2)CC1 +Cn1cnc(Nc2nccc(-c3ccc(N4CCCC4)c(C#N)c3)n2)c1 +COc1cc(C2=C(c3c[nH]c4cccnc34)C(=O)NC2=O)cc(OC)c1OC +O=C1c2c(cc(Cl)cc2C(F)(F)F)C2CNCCN12 +CC1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2CN1c1ccnc2[nH]cnc12 +C=CCCCC(=O)OC(C)C1CN(C(=O)CCC=C)C1=O +Cc1nc(C2CCOC2)c2c(N3CCc4cnn(C5CC5)c4C3)ncnn12 +Oc1cc(CC2CCN(CCc3ccc4c(c3)C(O)CCO4)CC2)ccc1Br +C#CCCCN1C(=O)C(C2=NP(=O)(OCC)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)C1C(C)(C)C +Cc1nc(NCc2ccc(C(C)(C)C)cc2)nc(C(F)(F)F)n1 +CN(CCc1ccccn1)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(Cl)cc(Cl)cn12 +CCOC1CN(C2CCC(O)(c3ccc4c(c3)OCO4)CC2)CC1NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 +CCNC1CN(CCCO[N+](=O)[O-])S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2cccc(CNC(=O)Cn3ccnc3)c2)n1 +CCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCC +CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nc2ccccc2n1-c1c(Cl)cccc1Cl +O=C(NCC1CCOCC1)c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1C(F)(F)F +O=c1cc(C(F)(F)F)c2cc(NCC(F)(F)F)ccc2[nH]1 +COc1cc(Cn2c3ccccc3c(=O)c3cc(NC(=O)CCCCCN)ccc32)cc(OC)c1 +CC#CC(=O)N1CCC(n2cc(C#Cc3cc(OC)cc(OC)c3)c3c(N)ncnc32)C1 +Cc1ccc(NC(=O)C2C3(C)CCC(C3)C2(C)C)cc1S(=O)(=O)N1CCOCC1 +N=C(N)c1cccc(C2Oc3ccccc3N(CCCCCN3CCOCC3)C2=O)c1 +O=C(OCC12CCN(CC1)CC2)c1c[nH]c2ccccc12 +Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(N5CCCC5=O)cc4)c3Cl)cccn2c1Br +c1ccc(CNCc2ccc(CC3CCNCCCOCCCNCC3)cc2)nc1 +Cc1ccc(OC(=O)N(CC(=O)O)Cc2cccc(OCc3nc(-c4cccc(Cl)c4)oc3C)c2)cc1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(Cl)cnc1NCc1c[nH]cn1 +Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3OCC(=O)N(C)C)c2n1 +Cc1nn2c(O)cc(-c3ccc([N+](=O)[O-])cc3)nc2c1-c1ccccc1 +N#CCNC(=O)C1(NC(=O)c2cccc(Br)c2)CCCCC1 +NS(=O)(=O)c1ccc(OCC(c2ccccc2)c2ccccc2)cc1 +Cc1cc(C2CCN(C(=O)C3CC(C)(N(C)C)CC3c3ccc(F)cc3F)CC2)n(-c2cc(Cl)ccc2Cl)n1 +O=C(O)c1cc(=O)c2c(ccc3c(=O)cc(C(=O)O)[nH]c32)[nH]1 +Cc1ccc2c(c1)-c1nc(N)nc(C3CCC(Br)O3)c1C2 +COc1cccc(-c2cc3cc4c(cc3o2)OC(C(C)(C)O)C4)c1 +CN1CCN(c2ccc(Nc3nc4c(-c5ccc(S(=O)(=O)N(C)C)cc5)cccn4n3)cc2)CC1 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+O=C(NC(c1ccc(F)cc1)c1ccc(F)cc1)C1CCC(N2CCOCC2)CC1c1ccccc1F +CN(C)CCC(Oc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1)c1ccccc1 +CC(=O)N1CCN(S(=O)(=O)c2ccc(OCc3ccccc3C)cc2)C(C(=O)NO)C1C +CC(C)CN(Cc1ccc(N2CCN(C(=O)C3(O)CC3)CC2)cc1)S(=O)(=O)Cc1ccccc1 +CC1CCCCN1C1(C(=O)N2CC(S(=O)(=O)c3ccccc3Cl)CC2C(=O)NC2(C#N)CC2)CC1 +O=C(O)CCC1(c2cccc(C(F)(F)F)c2)CCCN(C(=O)Nc2ccc(Cl)cc2)C1 +CNC(=O)C1OC(n2cnc3c(NCc4cccc(Cl)c4)ncnc32)C(O)C1O +O=C(C=Cc1ccc(Br)cc1)N1CCN(Cc2cc(F)cc(F)c2)CC1 +CC(Nc1ncc(Cl)c(Nc2cc(C3CC3)[nH]n2)n1)c1ncc(F)cn1 +O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCN(Cc2cccc(Oc3ccccn3)c2)CC1 +Cn1cc(Nc2ncc(C(F)(F)F)c(NC3C4C=CC(C4)C3C(=O)NCCO)n2)cn1 +CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CN(C(=O)Nc2cccc3ccccc23)CCN1Cc1ccccc1 +Oc1cccc(-c2ccc3c(-c4ccccc4)c(O)ccc3c2)c1 +CCOc1cc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(Cl)c3)c2cc1NC(=O)C(F)=CCN(C)C +CNC(=O)c1ccc2c(c1)S(=O)(=O)c1ccc(C(C)O)cc1C2=O +O=C(CCN1CCCCC1)N1CCN(c2ccnc3cc(Cl)ccc23)CCN(c2ccnc3cc(Cl)ccc23)CC1 +CN(C)CCOc1ccc2c3c(oc2c1)C(=O)c1ccccc1C3=O 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+Cc1[nH]c(Cl)c(C)c1-c1ccnc(Nc2ccc(F)cc2)n1 +COc1ccc(C(=O)NCCCCN2CCN(c3nsc4ccccc34)CC2)cc1 +O=c1[nH]nc2c3c([nH]c4cc(F)cc1c43)CCCC2 +CN(C)Cc1cc2nc(-c3cccc(O)c3)nc(N3CCOCC3)c2s1 +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCCCN(C)CCCCNc4c5c(nc6ccccc46)CCCC5)c3C(C1)C2 +CC(C)(O)c1cc2nc(-c3cnc(N)nc3)nc(N3CCOCC3)c2s1 +Oc1cnc(-c2ccc(F)cc2)c(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1 +Cn1cc(-c2cnc(N)c(-c3ccc(C(=O)NCc4cccc(S(C)(=O)=O)c4)c(F)c3)n2)[n+](C)c1 +CNC(=O)C(CC(C)C)N(Cc1ccc(OC)cc1)S(=O)(=O)c1ccc(Cl)cc1 +Cc1ccc(NC(=O)c2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2ccccn12 +Cn1c(-c2cccc(F)c2)nc2c(N)nc(C#CC3(O)CCCCC3)nc21 +CCC(Nc1c(Nc2cc(C)cc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)CC(=O)Nc1cc(NCC)cc(C(F)(F)F)c1 +CN1CCCC(O)(C#Cc2cc3c(cc2F)OCCc2sc(C(N)=O)nc2-3)C1=O +COC(=O)CC(Nc1nc2[nH]c(C)cc(=O)n2n1)c1cccc(Cl)c1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)cc3)nc(C(F)(F)F)c12 +CCCNC(=O)Nc1cccc(-c2ccc(CC(NC(=O)Oc3ccc(OC)cc3)C(=O)O)cc2)c1 +CC(C)(CO)C(=O)Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2Cn2ncnn2)o1 +CCCNc1nccc(N2CCC(Oc3ccc(C(C)C(=O)NCC(F)F)cc3)C2)c1F +COc1ccc(C2CCN(CC3CCC(NC(=O)C=Cc4cc(F)cc(F)c4)C3)CC2)cc1 +Cc1ccc(C)c(OC(CCN2CCC(n3c(O)nc4ccccc43)CC2)C(C)C)c1 +N#Cc1ccccc1-c1cc(F)cc(-n2nnc(-c3ccccn3)n2)c1 +CC1(C)CCCN(CCCCCn2c3ccccc3c3ccccc32)C1 +CCCOc1ccc(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1 +COc1ccc(C(C)NCCc2cc(OC)c(NC(=O)Nc3cnc(C#N)cn3)cc2Cl)cc1 +COc1cc2c3c(cc4ccccc4c3c1OC)NC(=O)C2=O +O=C1NC(=O)C(=Cc2ccc(OCCOc3ccccc3Cl)cc2)S1 +COC(=O)c1cc2occc2n1CC(=O)c1cccc(F)c1 +Cc1cc(F)ccc1COc1ccc(S(=O)(=O)NCC(=O)NO)cc1 +Nc1nc2c(-c3cnc4ccccc4c3)nccc2[nH]1 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCC1CCc2n[nH]cc2C1 +CC(C)(C)OC(=O)N1CC=C(c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)CC1 +COc1cc(OCC(O)CNCCN2CCOCC2)c2c(c1)OC1COc3cc(OC)c(OC)cc3C1(O)C2=O +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)N(C)Cc1ccccc1 +O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1Cl +N=C(N)c1ccc(NC(=O)c2cc3cc4ccccc4cc3cc2O)cc1 +CCCCC(CC1(C(=O)Nc2nnc(CC)s2)CCCC1)C(=O)O +Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccc(Cl)cc3)c2)c1 +COc1ccc(S(=O)(=O)Nc2ccc(C)c(CC(=O)NCc3ccc(C(=N)N)cc3)c2O)cc1OC +Oc1ccc(CSc2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CCN1C2CCC1CC(c1ccnc3c(-c4ccc(C(F)(F)F)c5[nH]ncc45)c(-c4ccncc4)nn13)C2 +CC(O)(C(=O)Nc1ccc(S(=O)(=O)c2cccnc2)cc1)C(F)(F)F +Fc1ccc(CCN2CCN(CC(F)Cc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)cc1 +O=C(CCc1nc(-c2ccc(O)cn2)no1)Nc1ccccc1C(=O)O +CC(CCc1ccc(-c2ccc(Cl)cc2)cc1)(C(=O)NO)S(C)(=O)=O +CNCc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 +NC(=O)C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2 +CCCCOC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCC +CC(C)CN(C)C(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +O=C(O)c1nccc(-c2ccc(F)c(C(F)(F)F)c2)n1 +CC(C)c1cc(Nc2cc(OC3CCN(C)CC3)nc(NCc3cc(C(C)C)no3)n2)[nH]n1 +CC(C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1)NC(N)=O +NC1(Cc2ccc(Cl)cc2)CCN(c2ncnc3[nH]cnc23)CC1 +CC(C)=CCCC1(C)C=CC(OC(=O)C=C(C)C)C(C)(O)C=CC(=O)C(CCl)=CC1 +CC(=O)OCC12CCC(C)=CC1OC1C(O)C(OC(C)=O)C2(C)C12CO2 +O=C(N1CCOCC1)N1Cc2c(-c3ccc(F)cc3)ncn2-c2ccccc21 +CCCC(=O)OCC1(N(C(=O)CCC)c2ccccc2)CCN(CCc2cccs2)CC1 +CC(C)(C)OCCCn1c(NCc2ccccc2Cl)nc2nc(C(N)=O)ccc21 +N#CC1(NC(=O)Cc2nnc(Cc3nc4c(-c5ccccc5)cccc4s3)o2)CC1 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1CC1CCCCC1 +C=CC(=O)Nc1ccc2ncnc(Nc3ccc(C(C)C)cc3)c2c1 +Oc1ccc(-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)cc1 +COc1ccc2c(c1)C(=O)N(CC1(c3cc4ncccc4o3)NC(=O)N(COC(=O)C(C)(C)C)C1=O)C2 +Fc1ccc(-c2cc(NCCN3CCCC3)c3ccccc3n2)cc1 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(C(=O)CCCNS(=O)(=O)c2cccc3c(N(C)C)cccc23)CC1 +CC(C)n1cc(C(=O)c2ccnc(NC(=O)Cc3ccccc3Cl)c2)c2cnccc21 +CC(O)(CS(=O)(=O)c1ccc(N=C=S)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CCN(CC)C(=O)c1ccc(N(c2cccc(CNC)c2)C2CCN(Cc3ccccc3)CC2)cc1 +CCCN(CCc1ccccc1)C(=O)c1c(CC)nc2n1CCN2c1c(C)cc(C)cc1C +CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)(C)C(=O)Nc4ccccc4)cc3)cc2n(CCC)c1=O +OC1CCN(c2nccnc2Oc2ccc(Nc3ccccn3)cc2)C1 +N=C(N)c1ccc(CC(NC(=O)CNS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCC2)cc1 +CCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 +O=C(NCc1cnccn1)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +O=C(O)COCC1CCC(COC(=O)N(c2ccccc2)c2ccc(C(F)(F)F)cn2)CC1 +Cc1nnc(-c2ccc3c(c2)CN2CCC3(c3ccc(Cl)cc3)CC2)s1 +COC(=O)C1=C(Nc2ccc(Br)cc2)CC(c2ccc(Cl)cc2)N(c2ccc(Br)cc2)C1c1ccc(Cl)cc1 +CCCc1c(OCCCCOc2ccc3c(ccn3CC(=O)O)c2)ccc2c(C(F)(F)F)noc12 +Cn1c(N(Cc2ccc(C(=O)Nc3nnn[nH]3)cc2)C2CCC(C(C)(C)C)CC2)nc2cc(Br)ccc21 +O=C(O)c1ccccc1Oc1ccc(F)cc1NS(=O)(=O)c1ccc(Cl)cc1 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC2CCCCC2)C(=O)CCCO)c1 +O=C(CNC1C2CC3CC(C2)CC1C3)N1CCCC1B(O)O +OC(C#Cc1ccc2cc(-c3n[nH]c4cccnc34)[nH]c2c1)C1CCCC1 +CC(C)N1CCC(NC(=O)c2ccc(OC3CCN(C4CCC4)CC3)cc2Cl)CC1 +Cn1nnc(-c2c(F)cc(Cl)cc2-c2cnc(CNC(=O)N(O)C3CCCC3)c(F)c2)n1 +O=C(Cc1cnc[nH]1)NC(Cc1ccccc1)C(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(N4CCN(c5ccccn5)CC4)nc23)N1 +COC(=O)CCC1N=C(c2ccccc2)c2cc([N+](=O)[O-])ccc2NC1=O +C=CCN1CC(C)N(C(c2cccc(O)c2)c2cccc(C(=O)N(C)CCc3ccccc3)c2)CC1C +C=C1C(=O)OC2CC(C)C3CCC(O)C3(C)C(OC(C)=O)C12 +Cc1nc(S(C)(=O)=O)ccc1Oc1ncnc(OC2CCN(C(=O)C(C)(C)F)CC2)c1F +COc1cc(C(=O)NCc2ccc(Cl)cc2Cl)ccc1-c1cn[nH]c1 +N#Cc1cc(-c2ccnc(Nc3ccc(NC(=O)CN4CCOCC4)nc3)n2)cnc1N1CCCOCC1 +CCCCOc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Cc1ccc(-c2cc(NC(=O)c3ccccc3)on2)cc1 +CC1NC(c2ccnc(C#N)c2)=NC1(c1ccc(F)cc1)c1ccc(F)nc1 +Nc1ccc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CC(C)(O)C1CCC(NC(=O)c2cnc(-n3ccc4cc(F)cnc43)cc2NC2CC2)CC1 +CC(=O)OC(CCCN1CCN(c2ncc(F)cn2)CC1)c1ccc(F)cc1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2ccc(Cl)cc2F)C1 +CCCc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)N(CCC)CCC +CN(C)CCn1c2c3c(n[nH]c(=O)c4cc(F)cc1c34)CN(C(=O)C1CC1)C2 +Nc1nc2sc(CCCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)cc2c(=O)[nH]1 +O=C(NN=Cc1cccs1)c1cc(C23CC4CC(CC(C4)C2)C3)c2ccccc2n1 +CC(C)N(CCNC(=O)C1c2ccc(Oc3ccc(C=O)cc3)cc2CCN1C(=O)OC(C)(C)C)C(C)C +NC(=S)NN=C(c1cccc(Br)c1)c1ccc(F)c(Br)c1 +Cc1cc2ccc(OCc3ccc(CN(C)Cc4ccc(C#N)cc4)cc3)cc2oc1=O +O=C(NC1CCC(CNc2ccccc2)CC1)c1cccc(Cl)c1 +N=C(N)c1ccc(CNC(=O)CNC(=O)C(CO)NS(=O)(=O)Cc2ccccc2)cc1 +CCc1ncnc(-c2ccc(C(=O)NCCN3CCOCC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCOc1ccc(Cc2cc(C34OCC(CO)(O3)C(O)C(O)C4O)ccc2Cl)c(F)c1F +CC(=O)Oc1ccccc1C(=O)Oc1ccc(CCO)cc1 +CC1=C(Sc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)C2C(=O)NC(N)=NC2N1 +CNC(=O)c1cccc2c(Nc3cc(N)cc(CO)c3)c3ccccc3nc12 +Fc1ccc(CC2CCN(CCC#Cc3c[nH]cn3)CC2)cc1 +Cc1c(N(CCCCC(F)(F)F)S(=O)(=O)c2cccc(C#N)c2)sc2ccccc12 +O=C(NC1CNC1)c1cccn2c(=O)c3cc4ccccc4cc3nc12 +O=C(NO)C1C[S+]([O-])CN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +CC(=O)Nc1nc2c(Oc3cc(N4CCN(C(c5ccccc5)c5ccccc5)CC4)ncn3)cccc2s1 +O=C(Nc1ccc(-c2nc3cc(NC(=O)c4ccccc4Cl)ccc3[nH]2)cc1)c1ccccc1 +CNC(=O)C(NC(=O)C(CC(C)C)C(NCc1ccc2ccccc2c1)C(=O)NO)C(C)(C)C +CN1CCN(c2ncc(-c3cc(Cl)cc(Cl)c3Cl)c(N)n2)CC1 +CC(=O)NCC1OC2CC3(C)OC4C=CC5OC6C=CC7OC(C=CC=CC=O)C=CC7OC6CC5OC4CC3OC2CC1O +CC(C)c1cccc(NC(=O)c2cccc(N3CCc4c(cncc4C(=O)O)C3)c2)c1 +Fc1cc(Nc2nc(NCc3ccccc3)c3ccccc3n2)ccc1Cl +CC(C)(C)C(NC(=O)C(CCCc1ccccc1)CC(=O)O)C(=O)NC1CCCCC1 +CCOC(=O)c1c(Cc2cccc(Cl)c2)[nH]c2cc(-c3ccc(-c4ccccc4)cc3)c(O)cc12 +CCc1cccc(N(C)C(=N)Nc2cc(Br)cc(SC)c2Br)c1 +COC(=O)c1cccc(N2CCN(CC(=O)Nc3ccc(-c4nc5cc(C#N)cc(C)c5o4)cc3)CC2)c1 +CC(=O)c1sc(NC(=O)NC2CCN(CC(=O)N(C)C)CC2CN2CCCC(Cc3ccc(F)cc3)C2)nc1C +COc1sc(NC(=O)N2CCN(C(=O)C3CN(C(C)(C)C)CCN3)CC2)nc1C +O=C(O)Cn1nnc(-c2cnc(N3CC4(CCN(c5cc(F)ccc5Cl)CC4)C3)s2)n1 +CC(O)C(NC(=O)N1CCN(c2ccc(C#Cc3ccc(N4CCOCC4)cc3)cc2)CC1)C(=O)NO +CN1CCN(C(=O)c2cc3ccc(Br)cc3[nH]2)CC1 +CCCN(CCN1CCN(C(=O)c2cc3ccccc3o2)CC1)C1CCc2c(O)cccc2C1 +O=C(NC1(CO)CCCC1)c1nn(-c2ccc(F)cc2F)c2c1CC1CC21 +Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NCC2CC2)cn1 +Cc1cc(-c2cccc(OC(F)(F)F)c2)ccc1NC(=O)C1=C(C(=O)O)CCC1 +COc1cc(-c2ncn(C)c2-c2ccc3c(c2)c(Cl)cn3C)cc(Cl)c1OC +O=S(=O)(NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2)c1cccnc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCC(Nc3ccc(F)cc3)CC2)c2ccc(Cl)c(Cl)c2)CC1 +CC(C)CCC(=O)NC1CCC(CCN2CCC(c3cccc4c3CCO4)CC2)CC1 +O=C(OCc1ccccc1)c1c(Cl)c2c(c(CCn3cnc4c3NC=NCC4O)c1Cl)CCCC2 +FC(F)(Br)CNC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(CCC(F)(F)F)NC1CCC(CCN2CCC(c3cccc4c3CCO4)CC2)CC1 +O=C(NCc1ccccc1)c1cnc(NCCCn2ccnc2)nc1Nc1ccccc1 +O=C(Nc1ccc(Cl)cc1)c1c(NO)cc(-c2ccccc2)oc1=O +COc1ccc(-c2nn3c(-c4cnc(N5CCN(C)CC5)c(C(F)(F)F)c4)cnc3s2)cc1OC +CC(C)C1(c2cccc(-c3cccc(Cl)c3)c2)NC(=N)N(C)C1=O +CCc1cccc(CCC(O)CCC2C(O)CC(O)C2CCCCCCC(=O)O)c1 +O=C(C1CSCN1C(=O)CC1Cc2ccccc2C1)N1CCCC1 +COc1ccc(-c2ccc(S(=O)(=O)C(CCN3C(=O)c4ccccc4C3=O)C(=O)O)cc2)cc1 +O=C(NCC1(F)CNC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +COC1=CC=C2C3Cc4ccc(O)c5c4C2(CCN3C)C1O5 +Oc1ccc2c(c1)C1c3cc(O)c(O)cc3CCC1NC2 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C(S)c1ccccc1 +O=[N+]([O-])c1c(O)nc2cc(Cl)cc(Cl)c2c1O +O=C(NCCCCN1CCN(c2ccccc2OCCF)CC1)c1ccc(CCF)cc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CCC(C)CC3)c2)[nH]1 +CC(C)(O)Cn1c(=NC(=O)c2ccc(-c3cn[nH]c3)s2)[nH]c2cc(CN3CCCCC3CO)ccc21 +CCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 +CCCCNC(=O)c1ccc(OC2CCN(CC3CCCCC3)CC2)c(Cl)c1 +CC(Nc1nccc(N(CC2CCOCC2)C(=O)c2ccc3c(c2)CCO3)n1)c1ccccc1 +Cc1c(C(=O)Nc2ccncc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCC(=O)N1N=C2c3cc(OC)ccc3CCC2C1c1ccc(OC)cc1 +CC(C)CNC(=O)c1ccc(-c2ccccc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +CCN(CC)C1(CNC(=O)N2CCC(c3nc(-c4ccc5ccccc5n4)no3)CC2)CCCC1 +O=C(O)c1[nH]c(=O)[nH]c(=O)c1CCc1nccc2ccccc12 +COc1ccc2c3c1OC1C(=O)CCC4(NC(=O)CC=Cc5ccc(Cl)cc5)C(C2)N(CC2CC2)CCC314 +COC(=O)C1CCCCC1c1ccc(CNc2nccc(C)c2NC(=O)CC#N)cc1 +Cc1ccccc1-c1ccc(CCC(=O)Nc2ccccc2C(=O)O)cc1 +Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1ncnc2[nH]c(C3=CCC(N(C)C)CC3)cc12 +COc1ccc(CC=Cc2ccccc2C=CC(=O)NS(=O)(=O)c2cccs2)cc1 +Cc1ccccc1N1CCN(c2ccc(C(=O)NCCCN3CCCC3=O)cc2NC(=O)c2coc(C3CC3)n2)CC1 +CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3C#N)c2)c1Cl +CN1C2CCC1CC(OC(=O)N(Cc1cccs1)c1ccccc1)C2 +CN(C)c1ccc(CC(CS)C(=O)Nc2ccc(S(=O)(=O)O)cc2)cc1 +CC(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1nc3ccc(Cl)cc3s1)c1c(O)ccc(C#N)c12 +CCCOCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4c3[nH]c(=O)n4C)cc2)cc1 +COc1cccc(Nc2nc(-c3cccc(C(N)=O)c3)nc3c2cnn3C)c1 +Fc1ccccc1CSc1nnc(Nc2ccccc2-c2ccccc2)[nH]1 +CC(=O)N1CCN(CC(C)(C)c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCC(C)(C)CC3)c2)CC1 +CON(C1CCC2(C)C(CCC3C2CCC2(C)C(C4=CC(=O)OC4)CCC32O)C1)C1OC(CO)C(N)C(O)C1O +c1ccc2c(NCCOCCOCCNc3c4c(nc5ccccc35)CCCC4)c3c(nc2c1)CCCC3 +CCN1COc2ccc3nc4c(cc3c2C1)Cn1c-4cc2c(c1=O)COC(=O)C2(O)CC +CCc1ccc(-c2ccc(COC(=O)N3CCCC3C(=O)NC(C#N)CC(N)=O)cc2)cc1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCCCF)CCO1 +Cc1cnccc1-c1nccnc1OC1CC(Nc2nc3ccccc3s2)C1 +CN1CN(c2ccccc2)C2(CCN(CCCCOc3ccc4c(c3)NC(=O)CC4)CC2)C1=O +O=C(NC1CCN(CCCOc2ccc(F)cc2)CC1)c1ccccc1 +O=C(C1=CC(c2ccc(Br)cc2)CC(OCCCCO)O1)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +CN(C)C1CCN(CCn2nc(Nc3c(Cl)cccc3Cl)c3cnc(Nc4ccccc4)nc32)C1 +CSc1nc2ccc(C(N)=O)cn2c(=N)c1S(=O)(=O)c1ccccc1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCN(C)C2=O +O=C(O)CCn1cc(-c2cnc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +COc1cc(CNCCCN(C)C)ccc1OCc1ccc(F)cc1Cl +O=C(CN1CCCCC1)Nc1cc(CN2CCCCC2)cc(Nc2ccnc3cc(Cl)ccc23)c1 +Clc1ccc(-n2nc(-c3nnc(C4(c5ccccc5)CC4)o3)c(Cn3cncn3)c2-c2ccc(Br)cc2)c(Cl)c1 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+O=c1cc(-c2ccc(OC(F)(F)F)cc2)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1 +CC(Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(-c3ccncc3)nc2c1 +O=C(OCc1ccccc1)N1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +Cc1ccc(F)c(-c2cc(F)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1 +O=C(c1cccc(C(F)(F)F)c1F)N1CCc2c(nnn2-c2ncccn2)C1 +COc1cc(C(=O)c2csc(-c3ccccc3)n2)cc(OC)c1OCCN1C(=O)c2ccccc2C1=O +CC(O)c1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 +NC(=O)Cc1ccc(Nc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)cc1 +CC(C)(CN1CCOCC1)c1ccc(-n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)cc1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cnn(CCN5CCCC5)c4)nc23)cc1 +CCCCCCCNC(=O)C1Cc2c(sc3ccccc23)CN1 +CC(C)c1csc2ncnc(N3C4CCC3CC(COCCN3CCCC3)C4)c12 +NS(=O)(=O)c1ccc(C(=O)N2CCc3cc(O)ccc3C2c2ccccc2)cc1 +O=c1[nH]c(=S)ccn1C1OC(COP(=O)(O)OP(=O)(O)C(F)(F)P(=O)(O)O)C(O)C1O +O=C(NO)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +O=C(NC(Cc1ccccc1)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)N1CCCC1B(O)O)c1cnccn1 +COc1cccc(OC)c1-c1cc(C(=O)NC(CC(C)C)C(=O)O)nn1-c1ccnc2cc(Cl)ccc12 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+COc1nc(-c2ccc3c(c2)S(=O)(=O)c2ccccc2C3=O)no1 +COc1cc(N2C(=O)c3ccc(F)cc3C2=O)ccc1N(C)C +COC(Cc1ccc(NC(=O)CCCCC2CCSS2)cc1)C(=O)O +COc1cc(C=Cc2ccc3c(c2)oc(=O)n3C)cc(OC)c1OC +COc1ccc(C2CN(C)Cc3cc(OCCCN4CCN(C(=O)c5ccncc5)CC4)ccc32)cc1 +CCCCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3ccc(Cl)c(Cl)c3)CC2)cc1 +CCc1nn(Cc2cc(C)n(C)n2)c2cccc(NC(=O)c3cnc4cc(-c5cnn(C)c5)ccn34)c12 +CCOc1c(C)cc(SC)cc1CNCCCNc1cc(O)c2ccccc2n1 +CC(C)CC1C(=O)NC(C(=O)Nc2ccccc2)CCCCNC(=O)OCCCC1C(=O)NO +CNS(=O)(=O)c1ccc(N2CCOCC2)c(Nc2ncnc3[nH]c(-c4cccc(C(F)(F)F)c4)cc23)c1 +CC(C)(C)c1ccc(CNC(=O)c2ccc(NC(=O)c3cccc(CN4C(=O)OCC4Cc4ccccc4)c3)cc2)cc1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc4c(c3)NCCNC4=O)nc2n1 +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc2c(c1)CN(C(CCC(=O)O)C(=O)O)C2=O +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3(CC3)CN(Cc3ccc(F)cc3)C1=O)N2 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cccc(S(=O)(=O)NCCCC(=O)O)c2)c1 +O=C(Nc1nc(-c2ccccn2)nc2ccccc12)c1ccccc1 +COc1ccc(C=Cc2cc(OC)cc(OC)c2C=CC(=O)NCCCCl)cc1 +CC(C)NC(=O)c1cccc(-c2ccc3c(C=O)c(O)ccc3c2)n1 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+O=C(CNC(=O)c1cccn(Cc2ccc(F)c(F)c2)c1=O)Nc1ccc2c(c1)C(=Cc1cnc[nH]1)C(=O)N2 +Cc1cccc(NC(=O)c2cccnc2SCc2ccncc2)c1 +CC(C)COc1ccc(C(NC(=O)C(C)c2ccccc2)C2CCCN2)cc1 +CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)[n+]([O-])c1C=CC(=O)O +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1ccnc(-n2cccn2)c1 +CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc4nonc4c3)c2)cc1 +CC(C(=O)NCC(COC(=O)C(C)(C)C)Cc1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(Cl)c1 +NC(=O)c1cccc2[nH]c(-c3ccc(-n4ccc(CN5CCCCC5)c4)cc3)nc12 +COc1ccc(C(=O)NN=C(C)C(=NNc2ccc(S(N)(=O)=O)cc2)N2CCCCC2)cc1 +COc1cccc(N(C)C(=N)Nc2cccc3ccccc23)c1 +Cc1cn(C2CC(F)C(COCP(=O)(O)O)O2)c(=O)[nH]c1=O +O=C(NCc1ccc(Cl)cc1Cl)N1CCC(Cc2ccccn2)CC1 +O=c1[nH]c(=O)c2cc(-c3n[nH]cc3CN3C4CCC3CN(c3ccc(C(F)(F)F)cn3)C4)ccc2o1 +CC(=O)NC1CC2CCC(C1)N2CCOc1ccc(Oc2nc3ncccc3s2)cc1 +CCc1c(C)[nH]c(=O)c(N(CC)CC)c1Cc1cc(C)cc(C)c1 +O=C(Nc1ccc(C(=O)N2CCCc3c(Cl)[nH]c4cccc2c34)cc1)c1ccccc1-c1ccccc1 +Nc1cnc(-c2ccc(C3CCC3)c(OCC(O)CNc3ccn[nH]3)c2F)cn1 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(Cc3ccc(S(N)(=O)=O)cc3Cl)CC2)n1 +COc1cc(-c2cc3ncccc3c(OCC3CNC(=O)C3)n2)ccc1OC1CCS(=O)(=O)CC1 +N=C(N)SCc1cccc2c1sc1c(CSC(=N)N)cccc12 +COc1cc2[nH]c(C)c(-c3ccncc3)c(=O)c2cc1Cl +Nc1nccn2c(-c3ccc(OCCN4CCOCC4)cc3)nc(-c3ccc(Oc4ccccc4)cc3)c12 +Nc1c(S(=O)(=O)O)cc(Nc2ccc(O)cc2)c2c1C(=O)c1ccccc1C2=O +N#Cc1ccc(-n2nc(C(=O)N3CCCC(N)C3)cc2OCC(=O)N2CCOCC2)cc1 +CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(CO)c1 +Cc1ccc(NC(=O)c2ccnc(N3CCCC3)c2)cc1-c1ccc2c(N)noc2c1 +COc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CN(c3ccc(F)cc3)C2=O)cc1 +COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(CCN3CCN(c4ccccn4)CC3)c2c1 +O=C(O)C=Cc1cn(Cc2ccccc2F)c2ccccc12 +CC(C)[S+]([O-])c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COC(=O)C1CN(C(=O)c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)C1 +CN(c1ncnc2ccccc12)C1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 +Cc1nc(CC(C)C)cc(-c2nc(-c3cc(F)c(OC4CCC(=O)N(C)C4)cc3Cl)no2)n1 +NC(COc1cncc(-c2ccc3cnccc3c2)c1)Cc1ccc2ccccc2c1 +COc1ccc2c(c1O)CCCC=C2c1cc(OC)c(OC)c(OC)c1 +COc1cncc(-c2cncc(-c3ccc(Oc4ccccc4)cc3)n2)c1 +COC1CCC2(CC1)Cc1ccc(CCCC(C)C)cc1C21N=C(N)N(C)C1=O +O=C(O)CC(O)CC(O)COc1c(Cl)cc(Cl)cc1C(F)(F)C1CCCCC1 +COc1ccccc1N1CCN(CCCCCCCn2ncc(N3CCN(C(=O)c4ccco4)CC3)c(Cl)c2=O)CC1 +O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)C=Cc1ccccc1 +COc1ccnc2c1nc(CCn1c(=O)n(C)c3cccnc31)n2-c1ccccc1 +CC12CC3CC(C)(C1)CC(NCC(=O)N1CCCC1C#N)(C3)C2 +Nc1ccc2nc(-c3ccc(C4=NCCN4)cc3)sc2c1 +CCC(O)(CC)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)OC(C)(C)C)CC1 +Nc1ccc2c(c1)NC(=O)C2=C1Nc2ccccc2C1=NO +COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)c4ccccc4)nc3)c2cc1OC +Cc1ccc(C(=O)N2CC(F)(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C2(C)CCOCC2)nc1Cl +O=C(NC(=O)c1ccccc1)Nc1nc2ccccc2n2c(=O)n(-c3ccccc3)nc12 +CC(C)(C)OC(=O)NN(CCC1C=CCC1)c1nc(C#N)ncc1Br +CCCCCCSCC(NC(=O)CCC(N)C(=O)O)C(=O)NC(C(=O)O)c1ccccc1 +O=C(Nc1ccc(Cl)c(Cl)c1)Nc1cccc2cnccc12 +CC(=O)c1ccc2c(c1)Cc1cc3c(cc1-2)C(C)=CC(C)(C)N3 +CC1(O)CCCN(S(=O)(=O)c2ccc(OCc3cnccn3)cc2)C1C(=O)NO +COc1cc2ncc3c(c(-c4ccc(C#N)cc4F)nn3C)c2cc1OC(C(N)=O)c1ccc(F)cc1 +COc1ccc(C2=NN(C(=O)c3ccc(C)nc3)C(c3ccc(Cl)cc3)C2)cc1 +COc1cccc(-c2cc([N+](=O)[O-])cc3cc(C(O)(c4ccc(C#N)cc4)c4cncn4C)oc23)c1 +COc1ccc(CN2CCN(Cc3ccccc3)C(CCO)C2)cc1 +Cc1cccc(NC(=O)c2cccc3oc(=O)[nH]c23)n1 +Nc1nc2c(s1)CCC2C(=O)Nc1ccc(CC2CCC(C(O)c3ccccc3)N2)cc1 +COC(=O)c1cccc(-c2ccc(NCc3cncn3Cc3ccc(C#N)cc3)cc2-c2ccccc2)c1 +Cn1cncc1C(O)(c1ccc(Cl)cc1)c1cc2c3c(c1)c(-c1cccc(Cl)c1)cc(=O)n3CCO2 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccc(C#N)cc3)CC2)n1 +CN1CCN(C(=O)C(COCc2ccccc2)NC(=O)c2cccnc2Oc2c(Cl)cccc2Cl)CC1 +COc1ccc(C(=O)Nc2cccnc2NCC2CCN(c3ccncc3)CC2)cc1 +COc1ncccc1-c1nccnc1C1CN(c2ccc3ccccc3n2)C1 +Cc1ccc(N2CCC(N)CC2)c(NC(=O)c2nc(-c3ncccc3C(F)(F)F)cnc2N)n1 +CN(C)CCN1C(=O)c2ccc(S(C)(=O)=O)c3cc4ccccc4c(c23)C1=O +CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(C)C)NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O +COc1cc(CNCC2CCN(CCCCCC(c3ccc(F)cc3)c3ccc(F)cc3)C2)cc(OC)c1OC +CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2Cl)c(C#N)c1=O +Cc1c(C(=O)N2C3CCC2c2nnc(-c4ccccn4)n2C3)cccc1C(F)(F)F +O=C(NCCc1ccc(Cl)cc1)C1CCCN(c2ncc(F)cn2)C1 +O=C(c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1N1CCN(CCN2CCCC2)C(=O)C1)C1CC1 +O=C1C(=O)N(Cc2ccc([N+](=O)[O-])cc2)c2c(Br)cc(Br)cc21 +COc1cc(C(=O)Oc2cccc3c2C(=O)C=C(N2CC2)C3=O)cc(OC)c1OC +CNC(=O)COc1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cc1 +CCCn1c(=O)[nH]c2[nH]c(-c3ccccc3)nc2c1=O +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)OC(C)(C)C)sc2c1 +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C(F)(F)F +COCc1ccn2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c12 +CC12CC(c3ccccc3)CC(C1)N(CCN1CCN(c3cccc(Cl)c3)C1=O)C2 +Cc1cc(CN2CCN(C(C)C)CC2)cnc1-c1ccc(C(=O)Nc2ccccc2N)cc1 +CC(C)OC(=O)C1=CCCCC1S(=O)(=O)Cc1ccc(F)cc1Cl +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(C)n1)CC2 +CC(C#Cc1ccc2[nH]c(O)nc2c1)N1CCC(Cc2ccc(F)cc2)CC1 +CCOc1ccc(S(=O)(=O)Nc2cc(CC(=O)O)c(NS(=O)(=O)c3ccc(OCC)cc3)c3ccccc23)cc1 +CN(C)CCNC(=O)c1cccc2nc3ccc(Cl)cc3nc12 +O=C(O)C(O)=CC(=O)c1cccc(Cc2ccccc2)c1 +Cc1cc(C#N)cc2nc(-c3ccc(NC(=O)CC4CCN(C(=O)OC(C)(C)C)CC4)cc3)oc12 +O=S(=O)(c1cccc(Cl)c1)c1cn(C2CCNC2)c2ccccc12 +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCC(=O)O +CCOc1ccc(Cc2cc(C3OC([S+](C)[O-])C(O)C(O)C3O)c3c(c2Cl)CC(C)O3)cc1 +Cc1[nH]c2c(c1C(=O)N1CCOCC1)CCCC2=C1C(=O)Nc2ccc(F)cc21 +Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1nc2c([nH]1)CN(C)CC2 +CN(C)C(=S)NN=C(c1ccc(C(C)(C)C)cc1)c1ccccn1 +O=C(c1ccc2[nH]c(=O)[nH]c2c1)N1CCCC2c3ccccc3CCC21 +N#Cc1ccc(N2CCc3c(-n4ccc(-c5nccs5)n4)ccnc32)c(OC(F)(F)F)c1 +FC(F)(F)c1ccc(Nc2nc(NC3CC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +O=C(Nc1cc(-c2ccccc2)nn1-c1ccccc1)c1ccc(Cl)c(Cl)c1 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc(O)cc1 +CC(=O)N1CCN(C(=O)C=Cc2ccc(Sc3ccc4cc[nH]c4c3)c(Cl)c2)CC1 +Cn1cc(C2CCC(CCN3CCN(c4ccccn4)CC3)CC2)c2ccccc21 +NC1=NC2(CCO1)c1cc(NC(=O)c3ccc(Cl)cc3F)ccc1Oc1ncc(Br)cc12 +COc1cc2c(cc1OCCCN1CCN(CCN3C(=O)c4cccc5cccc(c45)C3=O)CC1)N=CC1CCCN1C2=O +CC(NC(=O)C1CC1)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3)C2)cc1 +O=C(Nc1ccc(-c2nc(-c3ccc(Cl)cc3)cs2)cc1)C1CCN(S(=O)(=O)c2cccs2)CC1 +CN(C)CCCNC(=O)c1nc(-c2ccc(Cl)c(O)c2)c(-c2ccncc2)[nH]1 +CCC#CCOc1cc(NC(=O)NC(C)c2ccccc2)ccc1OC +CNCC(=O)Nc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O +COc1ccc(CCC(C)(C)O)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12 +COc1ccc2c(c1)c(NC(=O)N1CC(F)CC1C(=O)Nc1cccc(OC(F)(F)F)c1F)cn2C(N)=O +O=C1c2c(cccc2OCC(O)CN2CCCCC2)CC1Cc1ccccc1 +CC1C(=O)N(C(C)(C)C)CCCN1C(=O)CC(N)Cc1cc(F)c(F)cc1F +COC1C(O)CCC2(C)C3CCC4(C)C(=O)CCC4C3CCC12 +CC1CCC(Oc2ccnc3c(F)cccc23)CN1C(=O)c1ccccc1-c1ccccn1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3cc(Cl)ccc3F)n[nH]c2C1(C)C +Cc1ncnc(-c2ccc(C(=O)N(C)C)c(F)c2)c1C#Cc1ccc(N)nc1 +CC(C)Cn1ncc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)c1-c1ccncc1 +CC(Oc1cc(C(=O)NC2(CC(N)=O)CS(=O)(=O)C2)ncc1C1(F)COC1)C(F)(F)F +O=C1c2ccc(F)cc2NC(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 +Clc1ccc(-c2c(-c3ccc(Cl)cc3Cl)nnn2Cc2ccccc2)cc1 +CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1cccc[n+]1[O-] +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)c5cnccn5)C4)c3C2)cc1C(F)(F)F +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCCC2c1ccncc1 +O=C(NC1CC1)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 +Cn1cc(Cc2cn(CCCC(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)c(SCc3ccc(F)cc3)nc2=O)cn1 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+Cc1cccc(-c2nc(-c3ccccc3F)[nH]c2-c2ccncc2)c1 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCc1ccccc1 +CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(C#Cc4cnccn4)c3)cc2C(F)(F)F)CC1 +COc1cc(Cc2ccc3c(-c4cnn(C)c4)cc(C(N)=O)nc3c2F)cc(C)n1 +CN(Cc1cc(F)cc(F)c1F)C(=O)C1(C)CCCCC1 +CC(=O)c1cc(-c2ccc(O)c(F)c2)nc2ccc(O)cc12 +CC1(O)CC2CCC1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C2(C)C +CC1=NC(C)=C(C(=O)O)C(c2cccc(Cl)c2)C1=C(O)OCC=CC1CCCCC1 +CC(C)Nc1nc2cnccc2nc1N1CCC(Oc2ccc(F)cc2F)CC1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(Nc4ccc(F)cc4F)nc23)N1 +CC(=O)Nc1cccc(Nc2nc3ccccc3n2-c2nc(C)nc(N)n2)c1 +CN(C)CC1CCN(c2c([S+](C)[O-])cnc3ccc(-c4ccc(O)c(Cl)c4)cc23)CC1 +N=C(N)SCCOC1CCC(C2CCC(O)(CC(=O)O)CC2)CC1 +CCN1CC(C)(C)Oc2nc(N3C4CCC3COC4)nc(-c3ccc(NC(=O)OCCO)cc3)c2C1=O +CC(C(=O)OC1C[N+]2(CC(=O)Nc3ccon3)CCC1CC2)(c1ccccc1)N1CCCCC1 +CSc1nn2cc(-c3nc4c(OC(C)C)cccc4o3)nc2s1 +COC(=O)C1=C(C)NC(N2CCOCC2)=NC1c1ccc(F)cc1Cl +CNC(=O)Nc1ccc(OC)c(NC(=O)NC(=O)c2cc(F)c(F)cc2Cl)c1 +NC(=O)N(O)CCC#Cc1ccc(CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)o1 +CC(NC(=O)c1c[nH]c2ncc(C3CC3)nc12)C1CCCCC1 +CNc1ncnn2c(C)nc(-c3cnn(C)c3-c3ccc(C(F)(F)F)cc3)c12 +CN(C)C(=O)Cn1cc(-c2cnc(NC(=O)C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)nn1 +CCCCCC(O)C=CC1CC(F)(F)C(=O)N1CCCCCCC(=O)O +Cc1[nH]nc(-c2cc(Cl)c(O)cc2O)c1-c1ccc2c(c1)OCCO2 +CCCOc1cccc2c1CC(C(=O)Nc1ccc(N(CC)CC)cc1)CC2 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1NS(C)(=O)=O +COc1ccc2nc(NCCCN3CCN(CCCNc4nc5ccc(OC)cc5n5cccc45)CC3)c3cccn3c2c1 +CN(C)C(=O)C(c1ccc(-c2ccc(F)cc2)cc1)C(N)C(=O)N1CC(F)(F)C1 +Cc1nc(N2CCCC2)nc2ccc(NC(=O)COc3ccc(C(F)(F)F)cc3)cc12 +O=C(C=Cc1ccc(Br)cc1)N1CCN(C(=O)c2cccc(B(O)O)c2)CC1 +CC(C)CN(NC(=O)c1ccnn1-c1ccccc1)c1nc(C#N)ncc1Cl +CC(=O)NC(CCCCNC(=O)C1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C)C(=O)NCc1ccccc1 +c1ccc(-c2nnc(C3CCN(Cc4ccc(-c5nnc6n5-c5cccnc5Nc5ccccc5-6)cc4)CC3)[nH]2)nc1 +COc1ccccc1N1CCN(CCCNc2ncc(C#N)cc2C(=O)N(C)C)CC1 +COc1cccc(-c2cccc(C3(c4ccccc4)NC(=N)N(C)C3=O)c2)c1 +Cc1cccc(C)c1CC(NC(=O)C(CCCN=C(N)N)NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCCC(N)=O +O=C(CCc1ccccc1)Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1 +Cc1ccc(NC(=O)c2occc2C)cc1-c1nc2ncccc2o1 +CN1CCN(CC(NC(=O)CC2CNC(=O)c3cc(-c4cc(Cl)ccc4F)cn32)C2CCCCC2)CC1 +Cc1nc(N)sc1CCCNC(N)=NC(=O)CCCCCCCC(=O)N=C(N)NCCCc1sc(N)nc1C +CC(=O)OC1CCC2(C)C(CCC3(C)C2Cc2cc4ccccc4n23)C1(C)C +CCc1nc(N)ccc1C#Cc1c(-c2ccc(C(=O)N3CCN(C)CC3)c(F)c2)ccnc1C +CCCN1CCC2CC3=Nc4ccccc4C3(CC)C3CCCC1C23 +[BH4]P(=O)(OCC1OC(n2cnc3c(N)nc(SC)nc32)C(O)C1O)OP(=O)(O)O +CC(C)(N)CC1CCN(C(=O)C(O)(c2ccccc2)C2CCC(F)(F)C2)CC1 +O=C(Cc1ccccc1F)Nc1onc(-c2ccc(F)cc2)c1-c1ccncn1 +c1ccc2nc(N3CCC(Oc4nccnc4N4CC5(COC5)C4)CC3)ccc2c1 +O=C(C1CCNC1)N1CCC(NS(=O)(=O)c2cc(S(=O)(=O)c3ccccc3)ccc2C(F)(F)F)CC1 +O=C(Nc1ccccc1C(=O)Nc1ccc2c(C(F)(F)F)cc(=O)oc2c1)c1ccccc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NN4CCOCC4)nc23)N1 +COCCOc1cncc(-c2cc3c(ccc4c5c([nH]c43)CCNC5=O)cn2)c1 +CN(C)c1ccc(CNC(=O)C(CSCC2CCCCC2)NC(=O)C2CSCN2C(=O)OC(C)(C)C)cc1 +Cc1cc(Cc2cccc(-c3ccccc3)c2)n(O)c(=O)c1 +Cn1nnc(-c2cccc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)c2)n1 +CN(C)c1nc(N)nc(-c2sc(NC(=O)c3ccco3)nc2-c2ccccc2)n1 +CCC(CC)c1ccc(Cl)c2nc(Oc3c(C)cc(C#N)cc3Cl)n(C)c12 +Nc1ncn(Cc2ccc(CCCCc3ccc(C[n+]4ccc(N5CCCC5)cc4)cc3)cc2)c2ncnc1-2 +N#Cc1ccc2cc1Oc1ccc3cccc(c3c1)C(=O)NCCNCc1cncn1C2 +Cc1ccc(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1F +Cc1cccc(CNc2cc(N3CCOCC3)cc(CSc3nc(CF)c(C)s3)n2)n1 +CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c1C(=O)NC2 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2ccc(C(C)C)n2)n1 +N#Cc1ccc2nc(Nc3cc(Cc4ccccc4)nc(NC4CCC(O)CC4)n3)sc2c1 +N#Cc1ccc(N2CC3(CN4CCC3CC4)OC2=O)s1 +Cc1c(CN(C)C(=O)C=Cc2cnc3c(c2)CNC(=O)CN3)oc2ccccc12 +OC(c1cnc(N2CCN(c3cccc(Cl)c3)CC2)s1)(C(F)(F)F)C(F)(F)F +Cn1cnc(S(=O)(=O)N(CCN(Cc2cncn2C)c2ccc(C#N)cc2)Cc2ccncc2)c1 +CC1=NC2(CCN(c3c(Cl)cncc3-c3ccc4c(c3)CS(=O)(=O)N4C)CC2)C(=O)N1 +Cc1nnc(CN(C(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)C(C)(C)C)o1 +NC(=NO)c1ccc(CN(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCCC2)cc1 +CCOC(=O)C1=C(C)N=C(SCCC(=O)O)NC1c1ccccc1OC +O=C(O)c1ccc(N2C(=O)C3ON(c4ccccc4)C(c4ccccc4)C3C2=O)cc1 +Cn1c(=O)[nH]c2ccc(-c3ccccc3Cl)c(CN)c21 +O=C1NC(=O)c2c1c1c3ccccc3n3c1c1c2c2ccccc2n1CC(O)CCC3 +Cn1nccc1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCSCC1 +Nc1nc(NCCNc2ncc(-c3ncc[nH]3)c(-c3ccc(F)cc3F)n2)ccc1[N+](=O)[O-] +O=c1cc(N2CCOCC2)nc(Cc2nc3cccc(F)c3o2)[nH]1 +COc1ccc(C(=O)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1 +COCCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccccc2)CC3C)n1 +Cc1c(C(C)c2c(Cl)cccc2Cl)nc(N(C)Cc2ccc([N+](=O)[O-])cc2)[nH]c1=O +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cc1 +O=C(CC1CN(Cc2ccccc2)CCN1c1ccnc(-n2ccnc2)n1)NCc1ccc2c(c1)OCO2 +CC(C)(CO)C1CC(Sc2ccccc2)c2cc([N+](=O)[O-])ccc2N1 +CCC(C)C(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccc(COC)cc2)cc1 +Cc1ccc(-c2ccc(OCCN(C)CC(=O)O)c(C(=O)c3cccs3)c2)cc1 +CCC1=NN(C(=O)c2ccccc2O)C(O)(c2ccccc2)C1 +NC(=O)C(=O)N1CC2CC(CN(C(=O)CN3CCCC(NS(=O)(=O)c4ccc5cc(Cl)ccc5c4)C3=O)C2)C1 +CCC(=O)N(c1ccccc1)C1CCN(C(=O)C(N)C(C)c2c(C)cc(O)cc2C)CC1 +CN1CCN(C(=O)CNc2ccnc3cc(Cl)ccc23)CC1 +CC1(O)CCC2C(CCC3C2CCC2(C)C(C(=O)Cn4cccn4)CCC32)C1 +CCCC(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1 +CN1CCN(CC(NC(=O)CC2CNC(=O)c3cc(-c4cccc(Cl)c4)cn32)C(C)(C)C)CC1 +COC(=O)Nc1nc2cc(Oc3cccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c3)ccc2[nH]1 +CC(C)n1cnc2c(NCc3ccc(-c4ccccn4)s3)nc(NC3CCC(N)CC3)nc21 +COCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(SC)cc1 +N#Cc1ncc(C(=O)NCCc2ccccc2)c(NCC2CCC(F)(F)CC2)n1 +COc1cnc2c(Nc3ccc(F)c(C4(CF)CC(C(F)(F)F)OC(N)=N4)c3)nccc2c1 +CN1CCN(NCc2ccc3c(c2)-c2nc(N)nc(-c4ccc(F)cc4)c2C3=O)CC1 +O=C(NCc1ccc(Cl)c(Cl)c1)N1CCCC1CN1CCCC1 +COc1ccccc1CNC(=O)c1c(-c2ccccc2C)c2ccccc2c(=O)n1C +NCCCCCCNC(=O)N=C(N)NCCCC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CN(C(C)=O)C3)cc12 +COc1ccc2c(ccn2S(=O)(=O)c2cccc(C(=O)Nc3ccc(C)cc3C(=O)O)c2)c1C +Cc1cccc(CNC2=NC(=Cc3c[nH]c4ncccc34)C(=O)N2)c1 +Cc1noc(C)c1COC(=O)c1ccc(-c2nc3ccccc3s2)s1 +CCN1CCCC1C(=O)NC12CC3CC(F)(CC(C1)c1ccccc13)C2 +CCC1(OC(=O)C[n+]2cccc(C(C)=O)c2)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 +N#CCCN1C(=O)C(Cc2c[nH]c3ccccc23)N=C(c2ccccc2F)c2ccccc21 +Nc1c(S(=O)(=O)O)cc(Nc2ccc3cc4ccccc4cc3c2)c2c1C(=O)c1ccccc1C2=O +Cc1ccnc(NC(=S)N2CCN(c3cccc(C(F)(F)F)c3)CC2)c1 +Oc1ccc(-c2c(Cl)c3cc(O)ccc3n2Cc2ccc(OCCN3CCCCCC3)cc2)cc1 +N=C(N)c1ccc(-c2ncc(-c3ccc(C(=N)N)nc3)cn2)cc1 +CN(C)CCCCn1c(CCc2ccccc2)nc2cc(C=CC(=O)NO)ccc21 +O=c1[nH]c(CCCN2CCC(c3ccc(F)cc3)CC2)nc2c(Cl)cccc12 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1 +O=C1NCCN1c1ccc(S(=O)(=O)Oc2ccc(Cl)cc2)cc1 +O=C(c1c(Oc2cc(F)ccc2F)n(-c2ccccc2)c2cccnc12)N1CCNCC1 +CCN(C(=O)OCc1ccccc1)C1CCN(C(C)CC(NC(=O)C2CCC2)c2ccccc2)CC1 +O=C(CCCCCCCCc1ccc(O)cc1)c1c(O)cccc1O +CC(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc21 +Cc1ccc(-c2noc(C3CC4(C3)OCCCO4)n2)cc1NC(=O)c1cnc2ccccn12 +CCOC(=O)C1(c2ccccc2)N=C(c2ccc(OC)cc2)N(Cc2ccccc2)C1c1ccc(NC(=N)N)cc1 +CN(C)c1ccc(-c2cc(=O)c3ccc(OCC(=O)NCCCNc4c5c(nc6ccccc46)CCCC5)cc3o2)cc1 +O=[N+]([O-])c1cnc(Sc2nnc(O)n2-c2ccc(OC(F)(F)F)cc2)s1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(F)nc3)cc2s1)S(=O)(=O)CCC(F)(F)F +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NCc1cc(Cl)ccc1F 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+O=C(NCc1cn(-c2ccccc2)nc1-c1ccccc1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 +C=C(c1cc(OC)c(OC)c(OC)c1)c1ccc2c(c1)c(C#N)cn2C +Cc1ccnc(NC(c2cccc(Cl)c2Cl)c2ccc3cccnc3c2O)c1 +CNC(=O)C12CC1C(n1cnc3c(NC4CCC4)nc(N=[N+]=[N-])nc31)C(O)C2O +CCCc1ccc(C(=O)Nc2ccccc2-c2nnn(-c3ccc(SC)cc3)n2)cc1 +O=C(CC(NC(=O)c1ccc(-c2ccccc2CN2CCOCC2)cc1)C(=O)N1CCCCC1)Nc1ccc(Cl)cn1 +CC(c1ccc(F)cc1)N1CCC(N2CCC(c3ccc(O)cc3)C(F)(F)C2)C1=O +CC(=O)N1CCc2ccc(N(C(=O)C=Cc3cccc([N+](=O)[O-])c3)C3CCN(CCC4CCCC4)CC3)cc21 +COc1cc(Cl)ccc1CC(C)C(=O)N1CCN(c2c(F)cccc2C(N)C(C)C)CC1 +COc1cc(NC(=S)n2cc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)n2)cc(OC)c1 +CCCCCCCOc1ccc(C(=O)Nc2cccc3c(=O)cc(-c4nn[nH]n4)oc23)cc1 +CCOC(=O)CCCCOc1cc(-c2ccccc2)nc2cccc(CC)c12 +CCc1cc2c(C(=O)Nc3c(Cl)c[n+]([O-])cc3Cl)cnc(OC(F)F)c2o1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CCNC(=O)c4ccccc4)c3)s2)nn1 +Cc1ccc(NC(=O)Nc2ccc(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)cc2)cc1 +CCN1C(C(=O)NC(Cc2ccccc2)C(=O)C(=O)NCCOC)Cc2cc3c(cc2S1(=O)=O)OCCO3 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+CCC(=O)c1ccc2c(c1)sc(=O)n2CCN1CCCC1 +CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC=CC3)c(Cc3ccccc3C(F)(F)F)sc21 +CC#CCC(C)C(O)C=CC1C(O)CC2(CCCCCN=[N+]=[N-])CC(=CCCCC(=O)O)CC12 +COc1cc(OC)cc(N(CC#Cc2cc(C#N)ccn2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C(OC(C(F)(F)F)C(F)(F)F)N1CC(c2ccn(-c3ccccc3)n2)C1 +CC(NC(=O)c1nc(N2CCC(F)(F)CC2)c2cnccn12)C(C)(C)C +COc1cc(O)cc(CCc2cccc(O)c2)c1-c1c(OC)cc(O)c2c1CCc1cc(O)ccc1-2 +Cc1cc(CC#N)cc(-c2c(O)nc3cc(Cl)c([N+](=O)[O-])cc3c2OCCC2CCCCN2)c1 +CCNC(=NS(=O)(=O)c1ccc(N)cc1)N1CC2(C=N1)CCNCC2 +COc1nc2c(cc1NCc1ccc(F)cc1)c(=O)c(C(=O)O)cn2C(CO)C(C)C +Cn1c(=O)c2c(nc3nc(NCCCN4CCN(c5cccc(Cl)c5)CC4)ccn32)n(C)c1=O +COCC(NC(=O)Nc1cc2[nH]nc(OC3CCOC3)c2cn1)c1ccccc1 +O=C(NO)c1ccc2c(c1)nc(CCc1ccccc1)n2CCCO +CC(=O)c1cccc2c1CCN1C(=O)CN=C(n3cnc(C4CCC4)c3)C=C21 +N#Cc1ccc(C(=O)Nc2ccc(Cl)c(-c3nc4ccccc4[nH]3)c2)cc1 +CCCCCCCCCCC(CC)(CC)C(=O)Nc1c(OC)cc(OC)cc1OC +Cc1cc(-c2nc3c(cnc4cccc(Cl)c43)[nH]2)on1 +COC(=O)C1=C(c2ccc(Cl)c(Cl)c2)CC2CC(O)C1N2C +Cc1nc2ccccc2c(Nc2ccc(N3CCN(C)CC3)cc2)c1C(C)C +CCc1cccc(NC(=N)Nc2cc(C(F)(F)F)cc(CC)c2Cl)c1 +CN(C)CCn1c(CC(C)(C)C)nc2cc(S(=O)(=O)C3CN(C)C3)ccc21 +C=CC(=O)Nc1cc(CCn2c(=O)c(-c3cc(OC)cc(OC)c3Cl)cc3cnc(NC)nc32)ccn1 +CN(C)CC(=O)N1CCC(CNC2CC2c2ccccc2)(Cc2cccc(C#N)c2)CC1 +NC1=NC(CF)(c2cc(Nc3ncccc3F)ccc2F)CC(C(F)(F)F)O1 +Cc1ccc(-c2c(NS(=O)(=O)c3ccc(Br)cc3)ncnc2OCCOc2ncc(Br)cn2)cc1 +O=C(NCC(CCN1CCC(N2CCCCC2)CC1)c1ccc(Cl)c(Cl)c1)Nc1cc(Cl)cc(Cl)c1 +COC(=O)C1CC(NC(=O)c2ccc(OC)cc2OC)CN1CC(c1ccccc1)c1ccccc1 +COc1cccc(-n2ncc3c(NN=Cc4ccc(OCCN(C)C)cc4)ncnc32)c1 +O=C(c1cnccc1Oc1ccc2ncsc2c1)N1CCN(C2CC2)c2ccccc21 +c1ccc(-c2csc3nc(N4CCC(COCCN5CC6CC5CO6)CC4)ncc23)cc1 +C#Cc1cccc(Nc2ncnc3cc(NC(=O)c4ccc(C(=O)Nc5ccccc5N)s4)ccc23)c1 +COC1CCC2(CC1)Cc1ccc(-c3cncc(F)c3)cc1C21N=C(N)N(C(C)C)C1=O +O=C(CCN1CCCC1)Nc1ccc2c(NC3CCCCC3)c3cc(NC(=O)CCN4CCCC4)ccc3nc2c1 +CC(NC(=O)C1(NC(=O)c2ccno2)COC1)c1ccc(-c2cc(Cl)cc(Cl)c2OCC(F)F)cc1F +CC(=O)N1CCOCC1COc1cc(Cl)c(-c2noc(-c3cc(C)nc(NC(C)C)c3)n2)cc1F +O=c1[nH]c(C2CCC(c3ccccc3)CC2)c(Cc2cccc(C(F)(F)F)c2)c(=O)[nH]1 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+COc1ccc2c(OCc3nnc4ccc(-c5cc(F)cc(F)c5)nn34)ccnc2c1 +Cc1noc(=O)c2ccc(NC(=O)C(O)(CC(C)(C)c3cccc4c3OCC4)C(F)(F)F)cc12 +CC(=O)C1=NN(c2ccc(S(N)(=O)=O)cc2)C(=C(C#N)C(=O)Nc2ccc(S(N)(=O)=O)cc2)S1 +O=C(O)CCOc1ccc(C2Oc3cc(O)ccc3C3=C2c2ccc(O)cc2OCC3)cc1 +COc1cc(C(=O)c2ccc3c(c2)c(C=O)cn3C)cc(OC)c1OC +O=C1CC(c2c(Cl)ccc(N3CCNCC3)c2Cl)CC(O)=C1Sc1ccccc1Cl +Nc1nccc2cc(CC(C(=O)O)N3CCC(NS(=O)(=O)c4cnc(N5CCC(F)(F)C5)s4)C3=O)c(Cl)cc12 +O=C(Nc1ccc(O)cc1)c1ccc2c(-c3nc4ccccc4[nH]3)n[nH]c2c1 +CC(O)c1nccc(N2CCN(c3nccc(-c4ccccc4)n3)CC2)n1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(Oc4cc(Cl)ccc4F)nc23)N1 +N#Cc1ccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)cc1 +O=C(O)C=CC(=O)Nc1cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)ccc1O +CC(C)(CNC(=O)C1CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +O=C(O)C1C(Cn2c(=O)nc3ccccn3c2=O)CCC1Sc1ccc(-c2ccc(Cl)cc2)cc1 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(OC(=O)NC1CCCCC1)C(=O)CO +CCCN(CCC)C(=O)C=Cc1c(-c2ccc(Cl)cc2)[nH]c2ccccc12 +CN(C)c1ccc(-c2nc3ncnc(N)c3cc2-c2ccc(C(C)(C)C)cc2)cc1 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+O=c1c(=Cc2ccccc2Cl)sc2nc3cc(Br)cnc3n12 +COc1cccc2c1nc(CCn1c(=O)n(C)c3cccnc31)n2-c1ccccc1 +Cc1nc(NCC2CC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CC(C)c1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 +O=C(O)CNC(=O)C1=C(O)CCN(Cc2cnc(Oc3ccc(C4CC4)cc3)cn2)C1=O +Oc1ccc(-c2nn(C3CCCCC3)c3c(Cl)cccc23)cc1 +Cc1ncn(-c2ccc(CN3CC(N)C(C(=O)N4CCCC4C#N)C3)cc2)n1 +CCOc1ccc(Cc2cc(C3OC(OCc4ccccc4)C(O)C(O)C3O)ccc2Cl)cc1 +N#Cc1ccc(-c2ccc(NCCC3CCN(Cc4ccccc4)CC3)nn2)cc1 +COc1ccc(OCc2ccc(COc3c(Cl)cccc3Cl)cc2)c(Cl)c1 +Cn1cncc1C(OCc1ccc(C#N)cc1-c1ccc(C#N)cc1)c1ccc(C#N)cc1 +COc1ccc(C(Cc2ccncc2)c2ccc(NS(=O)(=O)c3c(F)c(F)c(F)c(F)c3F)cc2)cc1OC1CCCC1 +O=C(NCCSSCCNC(=O)C(Cc1ccc(O)c(Br)c1)=NO)C(Cc1ccc(O)c(Br)c1)=NO +Cc1nn(-c2c(F)cccc2CN(C)C)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12 +Cc1ccc(-c2nn(CCCCN3CCN(CC4COc5ccccc5O4)CC3)c(=O)c3ccccc23)cc1 +CCS(=O)(=O)N1CCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4ccccc34)c2)CC1 +CS(=O)(=O)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3OCC3CC3)CC2)c(F)c1 +N#Cc1ccc(-c2n[nH]c3c2Cc2ccc(OCCCN4CCOCC4)cc2-3)cn1 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+COC(=N)NS(=O)(=O)c1ccccc1[N+](=O)[O-] +CCC(C1CC1)n1cc(Cl)nc(Nc2cc(C)c(C)cc2C)c1=O +COc1ccc(F)cc1C(C)(C)CC(O)(CN1CCC(=O)c2ccccc21)C(F)(F)F +CCCCOc1cc(C(=O)Nc2c(Br)cncc2Br)ccc1OC +CN(C)c1cc[n+](Cc2ccc(CCCCc3ccc(C[n+]4ccc(N(C)c5ccc(Cl)cc5)cc4)cc3)cc2)cc1 +COCCCNc1nc(-c2ccc(N3CCOCC3)cc2)cc2ncn(C)c(=O)c12 +CCC(=O)N1CCC(N2C(=O)N(c3ccc(F)cc3)Cc3cnc(Nc4ccc(N5CCN(C)CC5)c(C)c4)nc32)C1 +CNc1nc(Nc2ccc(C(=O)N3CCC(OC)CC3)cc2OC)ncc1Br +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C1COC(=O)N1 +O=C(CN1CCN(Cc2ccc(Cl)cc2)CC1)N1CCSc2ccccc21 +CC(NC(=O)Nc1cc2[nH]nc(C(=O)NCC3CCN(C4CC4)C3)c2cn1)c1ccccc1 +COc1cc(C(F)(F)F)ccc1N1C(=O)COc2cc(S(=O)(=O)Nc3nccs3)ccc21 +Cc1cc(CN2CCNCC2)ccc1C(=O)Cn1ncc(OCc2ccc(Cl)cn2)cc1=O +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc(NC)cc2)cc1 +COc1ccccc1-n1cc2nc(Cc3ccccc3)nc(N)c2n1 +Cc1cccc2cc(C(C)Nc3ncnc4[nH]cc(C#N)c34)n(-c3ccccc3)c(=O)c12 +C=Cc1c[nH]c(=O)c2c1cc(CCCN)c1ccc(-c3cn[nH]c3)cc12 +NC(=O)n1cc(NC(=O)N2CC(F)CC2C(=O)NCc2cccc(Cl)c2F)c2ccc(O)cc21 +CC(C)(C)c1cc(N2CCC(=O)NC2=O)cc(C(=O)Nc2cccc(NS(C)(=O)=O)c2)c1O +CC(NC(=O)N1CCC(C(=O)Nc2cnccn2)CC1)C(=O)NC(CCc1ccccc1)C(=O)NCc1ccccc1Cl +O=C(NCc1ccccc1)c1c(NO)cc(-c2ccccc2)oc1=O +Cc1nnc(C(C)C)n1C1CCN(CCC(NC(=O)C2CCC(F)(F)CC2)c2ccccc2)CC1 +CCCCC1CN(CC2CCC(OCC)CC2)C(=O)OC12CCN(C1CC3CN(C(=O)c4c(C)ncnc4C)CC3C1)CC2 +COc1ccc(C)cc1NC(=O)OC1CC2CCCC(C1)N2CCF +Cc1cc(-c2cnn(C(CO)CO)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +Cc1c(Nc2c(C#N)cncc2-c2cc3cc(CN4CCNCC4)ccc3o2)ccc2[nH]ccc12 +O=C(CCCCCC(NC(=O)c1ccccn1)C(=O)NCc1ccccc1)NO +COc1cc(OCc2csc(-c3ccc(CO)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +COc1cc(C(=O)N2CCS(=O)(=O)CC2)ccc1Nc1cc2cc(-c3cnn(CC(C)(C)O)c3)ccc2cn1 +CCOC(Cc1ccc(OCCC2c3ccccc3-c3ccccc32)cc1)C(=O)O +O=C1c2ccc(O)cc2C23CCCCC2C1N(CC1CCC1)CC3 +O=C1CC(C(=O)O)Oc2ccc(OCc3cccc(OCc4ccc5ccccc5n4)c3)cc21 +O=C(NC1C(=O)N(c2ccccc2)CC1C(=O)O)c1ccc2ccccc2c1 +CC(c1ccc(-c2ccc(=O)n(C)c2)cc1)C(N)C(=O)N1CCC(F)C1 +Nc1c(C(=O)c2ccccc2Cl)cc[n+]([O-])c1-c1ccccc1Cl +Nc1cc2c3c(c1)c(C(F)(F)F)c(CCCc1ccccc1)n3CCC2 +COc1cc(NS(=O)(=O)Cc2ccc(Cl)cc2)ccc1-c1cncnc1C +CCNC(=O)C1OC(n2cnc3c(N)nc(N4CCN(c5ccc(OCC(=O)OCC)cc5)CC4)nc32)C(O)C1O +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C(F)(F)F)no4)c3)c2cc1OC +O=C(O)C1CCCN1C(=O)c1cccc(COc2ccc(-c3cccc4ccsc34)cc2)c1 +NS(=O)(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 +S=C(NN=C(c1ccccc1)c1ccccc1)N1CCNCC1 +NCCc1cc2c(O)c(c1)Cc1cc(CCN)cc(c1O)Cc1cc(CCN)cc(c1O)Cc1cc(CCN)cc(c1O)C2 +COc1ccc2nc(NC(=O)C3CC3c3ccc(C#N)cc3)sc2c1 +Cc1cc(C)cc(Oc2c(Cn3ccnc3Br)c(C)[nH]c(=O)c2I)c1 +O=C(NCC1CCCCN1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 +CCN(CC)c1cc2oc3cc(=[N+](CC)CC)ccc-3nc2c2ccccc12 +CC(C)N(C(=O)C1CCC2C3CNC4=CC(=O)CCC4(C)C3CCC12C)C(C)C +Oc1noc(C2CCNCC2)c1C(Br)c1ccc2ccccc2c1 +O=C1NCCCCC1N(Cc1cccnc1)S(=O)(=O)c1ccc(Cl)cc1 +CC#CC(=O)Nc1cc(-c2cnc3[nH]cc(Cl)c3c2)ccc1F +CC(NS(=O)(=O)c1ccc(-c2nc3cc(C(N)=O)ccc3[nH]2)cc1)c1ccccc1 +N#Cc1ccc(-c2cccnc2OC2CC(Nc3nc4ccccc4s3)C2)cn1 +NC1CCN(c2cc(Cl)ccc2C=C2SC(=O)NC2=O)C1 +CC(=O)c1cn(CC(=O)N2CC(C)(F)CC2C(=O)NCc2cccc(Cl)c2F)c2cnccc12 +O=S(=O)(c1cccc2ccccc12)c1n[nH]c2cccc(NCC3CCNCC3)c12 +O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(CN3CCOCC3)ccc1-2 +Nc1ncc(-c2ncccc2OC(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)(CO)CC1 +CC(C)C(C)Oc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N5CCN(C)CC5)cc4c3)n2)c1 +Cc1ccc(-c2ncccn2)c(C(=O)N2C3CCC2C(Nc2ccc(Br)cn2)C3)n1 +CC(C)c1ccc(S(=O)(=O)c2n[nH]c3ccc(N4CCC(N)CC4)cc23)cc1 +CCC(Cc1ccccc1C)NS(=O)(=O)c1c(C)cc(C)cc1C +O=Cc1c(O)ccc2nc(-c3ccc(C(=O)N4CCCC4)cc3)ccc12 +COc1ccccc1CNc1ccc2c(c1)n1ncc(I)c1n[n+]2[O-] +COC1CCN(c2c(NC(=O)c3nc(-c4ccccc4F)sc3N)cnn2C)CCC1N +O=C(CCCCCCOc1ccc(N(Cc2ccncc2)C(=O)CCc2c[nH]c3ccccc23)cc1)NO +CN1C(=O)NCC1C(=O)NCc1ccc(Cl)c(C(F)(F)F)c1 +OC1CCc2ccccc2C12CCN(CCc1ccccc1)CC2 +O=C(c1ccccc1)N1CCN(C(c2cncnc2)c2ccc(Cl)cc2F)CC1 +CCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NCc2ccc3ncccc3c2)C2CCC2)nn1 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(SCc3cccs3)c2[nH]1 +COC(=O)c1ccc(CNc2nc(Nc3cc(C)[nH]n3)cc(N3CCOCC3)n2)cc1 +Clc1ccc(-c2cc(C3CCN(Cc4ccccc4)C3)[nH]n2)cc1 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(Cc2ccccc2)C1 +COc1cccc(C=CCC(=O)Nc2nc3ccccc3c(=O)s2)c1 +CN1CCN(c2cccc(Nc3nc4c(OCc5ccccc5C(N)=O)cccn4n3)c2)CC1 +CSCC12CCC(=O)C=C1CCC1C3CCC(=O)C3(C)CCC12 +O=C1c2ccc(Cl)c(Cl)c2C(=O)N1CCCn1ccnc1 +CC1(c2sc(-c3cncc(C(F)(F)F)c3)cc2Cl)CS(=O)(=O)C2(CCOCC2)C(=N)N1 +N=c1oc2c(O)c(O)ccc2cc1C(=O)NCCNC(=O)c1cc2ccc(O)c(O)c2oc1=N +CN1CCN(c2ccc3c(c2)c(S(=O)(=O)c2cccc4ccccc24)nn3Cc2ccccc2)CC1 +Fc1cccc(COc2ccc(Nc3ncnc4ccc(NC(=S)NCCN5CCCCC5)cc34)cc2Cl)c1 +Cn1c(=O)n(C)c2cc(-c3[nH]cnc3-c3ccccc3)ccc21 +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(c2ccccc2)CC1 +O=C(NCCN1CCOCC1)c1cc(N2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-] +COC(=O)CS(=O)(=O)c1nc2ccc(S(=O)(=O)N3CCOCC3)cc2c2c1C(=O)N(CCOC(C)=O)C2=O +CN1C(Cc2c[nH]c3ccc(-n4cnnc4)cc23)CC2CN(CCc3cccc(F)c3)CC21 +NCCCCC(NC(=O)CCCCCNC(=O)C1OC(n2cnc3c(N)ncnc32)C(O)C1O)C(N)=O +CCN1C(=O)C2(CCc3cc(OC)ccc32)C(=O)N(c2ccccc2)c2cc(C(F)(F)F)ccc21 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1Oc1ccc2ccccc2c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(C=NOC(C)(C)C)c(O)ccc3nc2-1 +Cc1ccc2cc(Cn3cc(C(=O)NCc4ccc(N)nc4C)cn3)ccc2n1 +CC1(C)CC(NC(=O)Nc2ccc3c(c2)NC(=O)CC3)c2ccc(Cl)c(F)c2O1 +CC(C)N(Cc1nc2c(c(=O)[nH]1)COCC2)C(=O)CN1CCC(C(=O)c2ccc(F)cc2)CC1 +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NCc1nnn(C)n1 +CCOC(=O)C(c1ccccc1)N1C(=O)C(C)Oc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21 +CCCNc1cc(NCCSCc2ccc(CN(C)C)o2)c([N+](=O)[O-])cc1[N+](=O)[O-] +O=c1ccc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n1C1CCCC1 +CC1CCC2C(C)C(CC(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)OC3OC4(C)CCC1C32O4 +O=S(=O)(c1ccccc1)N(c1ccccc1)c1ccccc1 +CNc1ncc(-c2ccnc(NC3CCC(N)CC3)n2)c(CC2CC2)n1 +COC(C)(C)CC1n2cncc2CN(C(C)c2ccc(Cl)cc2)S1(=O)=O +COCCNc1ncc2ncnc(Nc3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3C)c2n1 +Cc1nc(-c2ccc(OCCCOc3ccc4c(c3)CCC4CC(=O)O)cc2)sc1C(=O)O +CCN(C(=O)c1ccc(-c2ccc(OC)cc2)[nH]c1=O)c1ccc(OC)nc1 +CCOc1cccc(C=NNc2ccc(S(=O)(=O)N(CC)CC)cn2)c1O +c1coc(CNc2ncc(-c3ccc(CN4CCCC4)cc3)c3nncn23)c1 +O=C(c1ccc2[nH]c(=O)c3c(c2c1)CCSC3)N1CCN(CCc2ccccc2)CC1 +CC(=NNC(=O)C1CC1c1ccccc1)c1cccc(O)c1 +O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc21 +COc1ccc(NCCNC(=O)C(CC2CCCCC2)NC(=O)c2cccc(Oc3ccccc3)c2)cc1 +Cc1nc(O)c2c(n1)CCc1ccc(S(=O)(=O)Nc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)cc1-2 +CNC(=O)c1csc(NC(=O)c2ccc3[nH]c4c(c3c2)C(C)CNC4=O)n1 +N=C(N)NCCCNc1ccnc2c1ccc1c(NCCCNC(=N)N)ccnc12 +CCCCOc1ccc(OC(=O)Nc2cc(Cl)ccc2OC)cc1 +CC(C)(C)c1cc2[nH]c(=O)n(O)c(=O)c2s1 +CNCCCN1Cc2ccccc2N(c2ccccc2)S1(=O)=O +COc1ccc(-c2cc(=O)[nH]c(=S)n2CC(=O)NCCN)c(OC)c1 +COc1ccc(NC(=N)NCCCOc2ccc(F)cc2)cc1 +O=C1c2ccccc2CCCN1CCCCN1CCN(c2nsc3ccccc23)CC1 +CCCCCNC(=O)NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Oc1cccc(Cl)c1 +NC(=O)COc1cccc(C=C2SC(=S)N(CC(=O)O)C2=O)c1 +CN(c1ccc(S(=O)(=O)NC2c3ccccc3CC2O)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +CN1CC2CC1CN2c1cnc(-c2ccc3[nH]ncc3c2)cn1 +COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3nccnc23)c1Cl +O=C(c1ccccc1)N(N=C1C(Cl)=C(Cl)C(Cl)=C1Cl)C(=O)c1ccccc1 +COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC(C)(C)C1 +CC(C)c1nc(-c2ccccc2)cc(-c2ccc(F)cc2)c1C=CC1CC(O)CC(=O)O1 +N=C(NCCCNCCCCCCCNCCCNC(=N)NCc1ccccc1)NCc1ccccc1 +Cc1ccc(S(=O)(=O)N=S(C)(=O)n2cc3c(n2)CN(C2COC(c4cc(F)ccc4F)C(N)C2)C3)cc1 +Cc1cccc(CNc2ccc(-c3ccc(Cl)cc3)cc2)c1-c1ccc(C(=O)NCCC(=O)O)nc1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(Cl)cc2)n(-c2ccccc2)n1 +Oc1ccc(C2Oc3cc(O)c(Cl)c(O)c3C(Cl)C2O)cc1O +CC(C)(Cc1cc2ccccc2[nH]1)NCC(O)COc1ccccc1C#N +Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NN)cc1 +O=c1cc(-c2ccccc2)oc2c3c(ccc12)OCC=C3 +CCN1C(=O)CC(C)(C)c2cc(C)c(-c3cc(CCC(=O)O)ccc3OC(F)(F)F)cc21 +CC1(F)CC(C(=O)NC(CO)c2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 +CS(=O)(=O)CCOC12CCCCC1(S(=O)(=O)c1ccc(Cl)cc1)c1c(F)ccc(F)c1OC2 +CS(=O)(=O)Nc1ccc(C(O)(c2ccc(Cl)cc2)c2cccnc2)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2cccc(OC(C)C)c2)cc1 +CC1CCC(NC(=O)C(N)Cc2nc(-c3ccc(O)cn3)no2)=C(C(=O)O)C1 +O=C1CCC2(OCCCc3ccccc3)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +CCC1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1CC(C)C +CCCC1(CCC)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)=C(O)O1 +CCc1cccc(OC)c1NC(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)cc1 +CC#CNC(=O)C12CNCCC1(c1ccc(Cl)c(Cl)c1)C2 +COc1ccc(-c2nc3c(N4CCN(Cc5ccc(Cl)cc5)CC4)c(Br)cnc3[nH]2)cc1 +CC(C)(N)C1CCC(Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1 +CN(C)CCN1C(=O)CCc2cc(NC(=N)c3cccs3)ccc21 +O=C(Nc1ccc(Oc2ccc(Cl)cc2)cc1)c1cc(I)cc(I)c1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNCC4)no2)cc1Cl +NC(CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2C=Cc2ccccc21)C(=O)O +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)C2CCCCC2)c1 +CC1CCCN1c1cccc(Nc2cc(-c3ccc(OCCN4CCCC4)cc3)nn3ccnc23)n1 +COC(=O)CCCCC(=O)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1C(=O)NCc1cccnc1 +O=C(Nc1ccccc1C(=O)O)c1cc(O)c(-c2ccccc2)c(Oc2ccccc2)c1 +CC(C)n1c(=O)c(C(=O)NC2CC3CCC(C2)N3CCCCCCCN2CCOCC2)cc2ccccc21 +CCc1cc(SCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OC(F)C(=O)O +CC(C)n1cnc2c(NCc3ccc(-c4ccccc4Cl)cc3)nc(NC3CCC(N)CC3)nc21 +CCn1cnc2c(Nc3ccc(P(C)(C)=O)cc3)nc(NC3CCOCC3)nc21 +CCNCCNc1cc(-c2ccc(S(C)(=O)=O)cc2)c(C#N)c2nc3ccccc3n12 +C#Cc1cccc(CC(NC(=O)COC)C(O)CNC2CC3(CCC3)Oc3ncc(CC(C)(C)C)cc32)c1F +CC(CNc1cccc(S(C)(=O)=O)c1)NC(=O)C(CC1CCCCC1)Nc1nc2cccc(Cl)c2o1 +COc1ccc(-c2[se]ncc2-c2ccc(Cl)cc2)cc1 +CCN1CCN(c2cncc(-c3cn(-c4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4C)nn3)c2)CC1 +O=C(NC1CCOCC1)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 +CN(c1cc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)C1CCOCC1 +O=C(CCCCC1CCSS1)Nc1ccc2c(c1)CC(C(=O)O)OC2 +CCNC(=O)Nc1cc2c(-c3ccncc3)ccc(Oc3cccnc3)c2cn1 +CN1CCN=C1c1ccc(NC(=O)c2nnnn2-c2cc3ccccc3cc2F)c(F)c1 +O=C(c1ccccc1C(F)(F)F)N1CCC(Cc2ccccc2)CC1 +COc1cc(-c2ccc3nc(NC(C)=O)sc3c2)cnc1N +CN(CCCN1c2ccccc2CCc2ccccc21)CCOCCOCCN(C)CCCN1c2ccccc2CCc2ccccc21 +COCc1cc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)ccc1F +O=C1N=C(NCCc2cccc(Cl)c2)SC1=Cc1ccc2ncccc2c1 +Oc1c(CN2CCCCCC2)ccc2c1CCN(CCCC(c1ccccc1)c1ccccc1)C2 +Cc1cc(C(F)(F)F)ccc1Nc1nc(SC2CCOC2C)nc2c1CCN(c1ncccc1C(F)(F)F)CC2 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(-c3ccsc3)c2)CCCCC1 +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3CC=CCC3N(Cc3ccc(F)cc3)C1=O)N2 +COc1ccc(S(=O)(=O)c2ccc(C(C)N3CCN(C4CCN(C(=O)c5ccccc5C)CC4)CC3C)cc2)c(OC)c1 +O=C(c1ccccc1)N(Cc1cnccc1-c1ccccc1F)S(=O)(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1ccc(CCC(=O)N2CCN(C(=NC#N)Nc3ccccc3C)CC2c2ccccc2)cc1OC +Cc1ccc(S(=O)(=O)NC(C(=O)NC(C=O)CC(C)C)C(C)C)cc1 +CCCOc1cccc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)c1 +CC(=O)c1cnc2ccc(-c3cc(F)c(O)c(F)c3)nc2c1NC1CCC(CN(C)C)CC1 +O=C(O)c1ccc(-c2nc(-c3ccc4oc5c(C(=O)O)cccc5c4c3)cs2)cc1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(OC)c(C#N)c2)n1 +CCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(CN3Cc4ccc(OCC5CC5)cc4C(F)C3)cc2)s1 +O=C(Nn1c(=S)[nH]c2ccc(F)cc2c1=O)c1ccc(CN2CCCCC2)cc1 +COc1ccc(-c2c(-c3cc(Br)c(OC)c(OC)c3)ncn2C)cc1F +CS(=O)(=O)NC(=O)CCCc1c(-c2ccc(F)cc2)[nH]c2ccc(Br)cc12 +Cc1ccccc1C1CN(CCCc2cn(CCCN3CCN(c4ccccc4O)CC3)nn2)CCc2cc(O)c(O)cc21 +CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)N(C)C)cc3)c2)CC1 +COc1ccc2c(c1)OCC1C2C2=C(OC1(C)C)C1=C(C(=O)C2=O)C2c3ccc(OC)cc3OCC2C(C)(C)O1 +COc1cc(-c2ccc3ncnc(Nc4cccc5[nH]ncc45)c3c2)ccc1F +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(Br)c1 +O=C(NCCCN1CCN(c2ccccc2)CC1)c1ccc2c(c1)Cc1ccccc1-2 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+O=c1[nH]nc2[nH]c(CN3CCC(O)CC3)nc3cccc1c32 +CN1C(=N)NC(C)(c2sc(-c3ccnc(-c4cccnc4)c3)cc2F)CS1(=O)=O +CNC(C)C(=O)NC(C(=O)N1c2ccccc2CC1C(=O)Nc1c(F)cccc1F)C(C)C +CCNc1nc(N)nc2c1ncn2C1OC(C(=O)NC)C(O)C1O +CN1CCC=C(c2nsnc2SCCCCCCCSc2nsnc2C2=CCCN(C)C2)C1 +COc1ccc(-n2cnc3c(sc4ncnc(NCCCO)c43)c2=O)cc1 +CC1(C)C(O)C(C)(C)C1NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +O=CNC(=O)c1cnn2c1n[n+]([O-])c1ccc(Cl)cc12 +Cc1ccccc1C(=O)NN(C(=O)c1ccccc1Cl)C(C)(C)C +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccccc1Br +CCCCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCO +CCCCOC(=O)N1CCC(Oc2ncnc3c2CCN3c2ccc(S(C)(=O)=O)cc2F)CC1 +COc1ccc(C=CC(=O)c2ccc(OCC(=O)NCCCCCCNc3ccnc4cc(Cl)ccc34)cc2)cc1 +CN(C)c1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)CN4CCC(CN)CC4)cccc2-3)cc1 +N#Cc1nc(N2CC(S(=O)(=O)c3ccccc3C(F)(F)F)CC2C(N)=O)cc(C(F)(F)F)n1 +N#Cc1cc(-c2ccnc(Nc3nccc(C4CCNCC4)n3)c2)ccc1OC1CCOCC1 +Cn1cc(-c2ccc(Nc3ncc4ccnc(NCC(C)(C)C)c4n3)c(OC(F)(F)F)c2)cn1 +CC(=O)OCC1OC(CCON=C2C3CCn4c(=O)n(-c5ccccc5)c(=O)n4C3C(O)C3OC23)C=CC1OC(C)=O 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+CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)CNC)cc13)N(C)S(=O)(=O)CC2 +CC(C(=O)NCCCNc1c2c(nc3ccccc13)CCCC2)c1ccc(-c2ccccc2)c(F)c1 +CN1CN(C2CCC(CNC3(C#N)CC3)CC2)c2c(cnc3[nH]ccc23)C1=O +Cc1cc(C)nc(N2CC3CN(C(=O)c4cc(F)ccc4-c4ncco4)CC3C2)n1 +Cc1ccc(CN2CC(C)C(c3nn4c(C5CCOCC5)ncc4c(=O)[nH]3)C2)o1 +O=C(OC1(C2CCCC(c3cccc(F)c3)N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC(O)(C2CC2)CC1 +N#Cc1ccc(CN2CCCC(NC(=O)c3ccc4[nH]nc(-c5ccc6c(c5)CCO6)c4c3)C2)cc1 +CC(C)(NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1)c1nccs1 +COC(=O)c1cc(Br)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CCc1nc(N)nc(N)c1-c1ccc(N(CC)Cc2ccccc2)c([N+](=O)[O-])c1 +Nc1ccc(S(=O)(=O)n2cc(C3CCN(Cc4ccccc4)C3)c3ccccc32)cc1 +O=C(Nc1ccc(Cl)cc1)N1CCN(Cc2cnc3ccccc3c2)CC1 +COC(=O)C1Cc2ccc(OCCc3nc(-c4ccc(C(C)(C)C)cc4)oc3C)cc2OC1=O +COc1ccc(CN2C(=O)C(=CC=Cc3ccc(N(C)C)cc3)c3ccccc32)cc1 +O=C(Nc1ccc(N2CCCCC2)cc1)N1CCc2nc[nH]c2C1c1ccc(Cl)cc1 +N=C(N)c1ccc(CNC(=O)C2CCCN2C(=O)C(CC(=O)N2CCOCC2)NS(=O)(=O)Cc2ccccc2)cc1 +Cc1ccc(C)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc32)c1 +O=C(O)C1(c2ccc3c(c2)OCC(Sc2ccccc2)C3O)CCCC1 +COC(=O)C(NC(=O)c1cc(-c2ccco2)nc2ccccc12)c1ccccc1 +Nc1ccc(-c2ccccc2F)cc1NC(=O)c1ccc(CNc2ccncc2)cc1 +Cn1c(C(=O)c2ccc(Oc3ncccc3-c3cc[nH]c(=O)c3)cc2)nc2ccccc21 +CCNS(=O)(=O)Oc1cc(C(C)(C)C)c(SC2=C(O)OC(CCc3ccc(O)cc3)(C(C)C)CC2=O)cc1C +Cc1ccc(CN2C(=O)CNC(c3ccccc3)(C(Oc3nc(C)cc(C)n3)C(=O)O)c3ccccc32)cc1 +CC1CN(c2ccc(C(=O)N(C)C)c(NS(=O)(=O)c3ccc(-c4ccccn4)s3)c2)CC(C)N1 +CC(OCC(O)CNC(C)(C)Cc1ccc2ccccc2c1)c1cccc(Cl)c1 +CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(C(N)=O)ccc2c1=O +O=C(NO)c1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c2cc(Cl)cc(Cl)c2)cc1 +Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c2ccccc12 +O=C(Nc1ccc(C(=O)N2CCCC23CCNC3)cc1)N1Cc2ccc(F)cc2C1 +CCC1(S(=O)(=O)c2ccc(Cl)cc2)CC(CO)Oc2c(F)ccc(F)c21 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(Cc2cccc(F)c2)C1 +O=C(NNc1ncnc2sc3c(c12)CCC3)c1ccccc1O +CC(=O)NCCNS(=O)(=O)c1cnc(-c2ccc(N(Cc3ccccc3)C(=O)c3ccc(O)cc3O)cc2)c(C)c1 +CC(NC(=O)C(C)(C)Oc1ccc(Cl)cc1)C(Cc1ccccc1Cl)c1ccccc1 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+COCCn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2sccc2Cl)CC3)cn1 +O=C(CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5ccccn5)n4)ccc3[nH]2)CC1)N1CCCC1 +CCc1ccccc1-n1nc(C)c(-c2ccc3nccnc3c2)c1Nc1ccc(OC)cc1C(=O)O +CCC(NC(=O)c1cc(C(=O)NCc2nccs2)c2n1CCOC2)c1ccccc1 +Cc1cccc(NC(=O)CN2CCC(c3cccc[n+]3[O-])CC2)c1 +O=C(O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(Br)c2)CCCC1 +Cn1c(=O)c2c(cc(-c3ccc4ccccc4c3)n2O)n(C)c1=O +COc1cccc(OC2=C(Cl)C(=O)c3c(OC(C)=O)ccc(OC(C)=O)c3C2=O)c1 +CCc1nc2c(C(F)(F)F)cccn2c1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1 +Cn1cnc2cc(Cl)c(NCc3ccc(C(=O)NCc4cccnc4)cc3)cc2c1=O +CC(C)CS(=O)(=O)N1CCC2(CCN(c3ccc(OC(F)(F)F)cc3)C2=O)C(O)C1 +CC12Cc3cnn(-c4ccccc4)c3C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(=O)COc1cnc2ccccc2n1 +CCCCCCC(c1ccccc1)N1CCC(O)(c2ccccc2)CC1 +CCOC(=O)C1CN(CCNc2nc3ccccc3n(C3CC4CCC(C3)N4C3CCCCCCC3)c2=O)CC1C(=O)OCC +CNC(=O)c1cc2c(Oc3ccc(-n4ccnc4)cc3)cncc2s1 +Nc1nc(N)c2nc(CNc3ccc(C(=O)NC(CCCNC(=O)CCC(=O)O)C(=O)O)cc3)cnc2n1 +CCc1cc(Cc2ccc(C(=O)NC3CCOCC3C(=O)NO)cc2)c2ccccc2n1 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+CC(C)c1cc(-c2ccccc2)c(-c2ccc(S(C)(=O)=O)cc2)c(=O)o1 +CC(C)CCc1nc(-c2ccc(OCCCN3CCCN(C(=O)C(C)NC(=O)c4ccco4)CC3)cc2F)no1 +NC1CCC(Nc2ccc3ncc(-c4ccc(Nc5ncccc5F)cc4)n3n2)CC1 +O=[N+]([O-])c1cn2c(n1)OC(COCc1ccc(OC(F)(F)F)cc1)C2 +Clc1cccc(N2CCN(CCCCn3cc(-c4ccc(-c5ccccc5)cc4)nn3)CC2)c1Cl +c1cncc(CN(CCCNCc2ccc3c(c2)OCO3)c2nc(-n3ccnc3)ns2)c1 +CN1CC(C(=O)c2cccs2)C(c2ccc(Cl)cc2)C1 +CCCN(CCC)C(=O)C1OC(C(=O)O)=CC(N)C1NC(C)=O +O=c1[nH]c2c(cc1CNCc1cccc(C(F)(F)F)c1)c(C1CC1)nn2-c1ccccc1 +CC(C)C(=O)N(CC=Cc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21)C(C)c1cc(F)cc(F)c1 +CCCN(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)C(c1ccc(Cl)cc1)C(C)C(=O)O +O=C(NN1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCc1c-2cccc1[N+](=O)[O-] +COC(=O)c1ccc(NC(=O)c2c(NO)cc(-c3ccccc3)oc2=O)cc1 +CCS(=O)(=O)CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(-c4cnn(C)c4)c2)CC3)n1 +CC(C)(C)C(=O)SCCOP(=O)(COCCn1cnc2c(N)ncnc21)OCCSC(=O)C(C)(C)C +CN(C)CCCOc1ccc(Nc2ncnc3ccccc23)c(CN(C)C)c1 +CN1CCSCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +Fc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 +Fc1ccc(OCCOc2c(-c3ccccc3)nc3ccccn23)cc1 +O=C(NC1CCS(=O)(=O)CC1)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O +COC1(c2cc(F)cc(OCc3cc(-c4ccccc4)n(-c4ccc(C)c(C)c4)n3)c2)CCOCC1 +CCc1cccc(CC)c1-c1cc(OC)c2c(n1)CCCC2Nc1cc(OC)ccc1C +CCN(C)C(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(N(CCN(C)C)C(C)=O)cc1)c1ccccc1 +CCNC(=O)C1OC(n2cnc3c(N)nc(NCCc4ccc(CCC(=O)OC)cc4)nc32)C(O)C1O +COc1ccc2c(c1)c1c(n2Cc2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)CCN(CCC(=O)O)C1 +CC(=O)OCC12C(=O)C=CC(O)C13OC3CC1C3CCC(C(C)C4CC(C)=C(C)C(=O)O4)C3(C)CCC12 +COc1cc(Nc2ncc3ccn(-c4cccc(C(=O)NCCN5CCCC5)c4)c3n2)cc(OC)c1OC +Cc1cc(O)cc(C)c1CC(N)C(=O)NC1CCCc2ccc(Cc3cccc4ccccc34)cc21 +CC(C(=O)O)c1ccc(C(c2ccc(F)cc2)N2CCC(C(F)(F)F)CC2)c(-c2ccc(C(F)(F)F)cc2)c1 +CCc1c(C(=O)C(N)=O)c2c(CC(=O)O)cc(C)cc2n1Cc1ccccc1 +O=C(O)c1ccc2c(c1)nc(-c1ccc(OCc3ccccc3)cc1)n2C1CCCCC1 +CCN1C(=O)c2c(ncn2Cc2ccc(OC)c(Cl)c2)N2C1=NC1CCCC12 +CCC1CC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(C)=O)c2nc(OC)ccc2N1C(=O)OC(C)C +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-n2cncn2)c1 +CCCCCCC(=O)OC1c2cc3c(cc2C(c2cc(OC)c(OC)c(OC)c2)C2C(=O)OCC12)OCO3 +Cc1cc(Cl)c(OCCOc2ccc(C3=C(C(=O)N(Cc4cccc(Cl)c4Cl)C4CC4)CNCC3)cc2)c(Cl)c1 +CCc1nn(Cc2ccc(NC(=O)C(C)(C)C)cc2)c(CC)c1CC(=O)O +Cc1nc(N)nc(-c2cccnc2Nc2cnc(C)c(NS(C)(=O)=O)c2)n1 +CN(c1ccccc1)c1ncc(Br)c(Nc2cc(C3CC3)[nH]n2)n1 +O=C(O)CS(=O)(=O)c1ccc(C(=O)NCC(c2cccnc2)N2CCOCC2)cn1 +COc1ccc2nc3cc(Cl)ccc3c(NCCCCCCCCCCCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1 +CC(C)Nc1cc(-n2ccc3cc(CNC(=O)C4CCOC4)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +O=C1NC(=O)c2c1c1c3ccccc3ncc1c1[nH]c3ccccc3c21 +COc1ccncc1C#Cc1c(Cl)nc(N)nc1NC1CC(CO)C(O)C1O +Cc1ccc(N2CCc3ncnc(NCc4ccc(Cl)nc4)c3C2)c(C#N)c1 +COC1CN(c2cccc(-c3cccc(C)c3OCc3cc(F)c4c(c3)CCN(C3CCOCC3)CC4)n2)CCC1C(=O)O +CCCc1ccc(C(=O)O)cc1CCn1cnc2c1NC=NCC2O +O=C(O)c1ccc2c(c1)nc(-c1ccc(O)cc1)n2C1CCCCC1 +COc1cc(-c2nccc3[nH]c(-c4cccc5cc[nH]c45)nc23)cc(OC)c1OC +Cc1nc(N)nc(-c2cc(C(C)N3CCN(S(C)(=O)=O)CC3)cnc2Nc2cc(F)c3cccnc3c2)n1 +c1nc(NC2CCCCC2)c2cc(OCCN3CCOCC3)ncc2n1 +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4ccc5nc[nH]c5c4)c3)ncnc12 +CCNC(=O)Nc1ccc2ncc(Nc3ccc(OC)c(OC)c3)nc2n1 +CCC1CCCC(C2(OC(=O)N3CCN(CCO)CC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCCNCC2)c(-c2cccnc2)c1 +CC(c1ccc(F)cc1)C(CS)C(=O)NC(Cc1ccc(O)cc1)C(=O)O +CCOC(=O)c1cc(Cc2ccc(Cl)cc2Cl)c(=O)n2c1CCC2 +COc1ccc(C(CS(C)(=O)=O)N2C(=O)c3ccccc3C2=O)cc1OC1CCCC1 +O=C(CN1CCCCC1)N1CCc2nc(-c3cc4cc(F)ccc4[nH]c3=O)[nH]c2C1 +CNC(=O)N1CCC(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +CNS1(O)CC(C)(c2cc(NC(=O)c3cnc(OC)cn3)ccc2F)NC(=N)C1(C)C +COC(=O)C1(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCC(C)(C)CC3)c2)CCOCC1 +Cc1cn(Cc2cccc(C#N)c2)c2c(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 +COC1CCC2(CC1)Cc1ccc(-c3cc(C#N)ccc3F)cc1C21N=C(C)C(N)=N1 +O=C(NC1CCCC1Nc1ccc(C(F)(F)F)cn1)c1ccccc1Cl +Cn1cc(C(=O)Nc2ccc3oc(SCc4cccc(Br)c4)nc3c2)c(C(F)F)n1 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(=NOC4CCN(C)CC4)C5)cn3)n2)s1 +O=C(c1cc2ncc(Cl)cn2n1)N1CCc2[nH]c(=O)sc2CC1 +CCC(CO)Nc1nc(Cc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1 +Cc1cccc(-c2cnc(N)c(C(=O)NC3CCCC3)n2)c1 +Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CCN(CCO)C3)CC2)nc1 +Cc1c(Cl)cccc1N1CCN(CCCCOc2ccc3c(n2)NC(=O)CC3)CC1 +COc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)OCO3)cc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(C(=O)c2ccccc2)CC1 +O=C1C(c2ccc(F)cc2)=COC12CCN(Cc1ccc(F)cc1)CC2 +COCCCS(=O)(=O)c1ncccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +O=C(NCc1nc2ccccc2[nH]1)C1=CC(c2csc3ccccc23)CC(OCCCCO)O1 +CN1CCC(C(Oc2ccc(F)cc2)c2ccccc2)CC1 +Brc1c(Br)c(Br)c2[nH]c(NCCN3CCN(c4ncccn4)CC3)nc2c1Br +CC[S+]([O-])(=NC)c1ccc(Nc2ncc(C(F)(F)F)c(NC3CCCC3N(C)C)n2)cc1 +O=C(Nc1cccc(Br)c1)NC1CCC(OCc2c(F)cccc2F)CC1 +CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1cccc2ccccc12 +Cc1c(S(=O)(=O)Nc2cncc(C(=O)O)c2)sc2ccc(C(C)C)cc12 +COC(C(=O)NC1CCC(OC(=O)CCc2ccccc2)CNC1=O)C(O)C(O)C(O)C=CC(C)(C)C +CNc1ccc(C(C)(C)C(=O)NC2C3CC4CC2CC(CC(N)=O)(C4)C3)cn1 +CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCOCC4)cc3)c2n1 +CC(C)CC(CP(=O)(O)C(N)CCc1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O +CNC(=O)NCCCCP(=O)(O)CC(CCc1ccccc1)C(=O)NC(CC(C)C)C(=O)Nc1ccccc1 +CC(C)CNc1cc(NS(=O)(=O)c2cccc(-c3ccncc3)c2)cc2c(Cl)[nH]nc12 +c1ccc2c(c1)c1cc[n+]2CCCCC[n+]2ccc(c3ccccc32)NCCCN1 +N#Cc1cccc(-c2ccc(N(CCN3CCC(O)C3)C(=O)Nc3ccc(F)c(C(F)(F)F)c3)cc2)c1 +COc1ccc(C(=O)Nc2ccc(F)c(C3(C(F)F)COCC(N)=N3)c2)nc1 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)OC)cc3c(c2n1Cc1ccccc1)CCCC3 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1ccccc1-n1cnnn1 +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CCC1C(=O)N1CCC1 +COc1n[nH]c2cc(NC(=O)NC(c3ccccc3)C3CCCO3)ncc12 +Cc1nc(N)nc(-c2cc(Cl)cnc2Nc2cnc(C)c(NS(C)(=O)=O)c2)n1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1c1nc2ccccc2[nH]1 +O=C(NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O)c1ccc2c(c1)nc(-c1ccoc1)n2C1CCCCC1 +Cn1c(C2(O)COC2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21 +Cc1ccc(NS(=O)(=O)NC(CNC(=O)CC2CC(c3ccc(C(=N)N)cc3)=NO2)C(=O)O)cc1 +O=C1NCCn2c1cc1cc(F)cc(-c3ccccc3)c12 +CC1(C)CC=C(c2cc(C3(O)CC4(CO)C=CC(CO)(C3)O4)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +O=C(O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c([S+]([O-])Cc3ccccc3)cccc21 +O=C(O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2cc3ccccc3cc12 +COc1ccccc1-c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1 +O=C(c1ccc(F)cc1)C1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1 +O=C(NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(=O)Nc1ccncc1)C1CCCCC1 +CCOc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)ccc1Cl +COc1ccc2c(C)cc(NC3CCCC(NCc4ccsc4)C3)nc2c1 +CC1OC(=O)C2CC3CC(NC(=O)OC(C)(C)C)CCC3C(C=Cc3ccc(-c4cccc(C#N)c4)cn3)C12 +COc1ccc(NCCNC(=O)C(Cc2ccc(Cl)cc2)NC(=O)c2cccc(C)c2)cc1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1 +Cc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(c1)CCc1ccccc1C2=O +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCCC2)c1 +COCCN(C)C(=O)C1CCN(Cc2cccc(NC(=O)c3cncc(C)c3)c2)CC1 +O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1Cc1ccc(OCCCN2CCCCC2)cc1 +Cc1ccc2c(c1C)NC(=O)C2(c1ccc(O)cc1)C1CCCCCC1 +CC#CC(=O)N1CCC2(CC(n3nc(-c4ccc(Oc5ccccc5)cn4)c4c(N)ncnc43)C2)C1 +Cc1ncc(C)n2nc(CCc3cc(O)c4cc(F)ccc4n3)nc12 +CSc1ccc(-c2ccc(C(=O)NC3CCN(Cc4ccccc4)C3)cc2)cc1 +C[Si](C)(C)C#Cc1ccc2[nH]c3cnc(C(=O)OCC(F)(F)F)cc3c2c1 +CCC(C(=O)Nc1cc(F)c(C(=O)O)c(F)c1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O +Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)NCCO)cc1 +CNC(=O)n1cc(NC(=O)N2C(C(=O)NC(CO)c3cccc(Cl)c3F)CC3CC32)c2ccccc21 +CC(NC(=O)Nc1cc2[nH]nc(N3CC(C)(O)C3)c2cn1)c1ccccc1 +CC(=O)Nc1n[nH]c2nc(N3CCCCC3)c3c(c12)CCN(Cc1ccccc1)C3 +O=C(O)CCC(O)c1ccc(C=Cc2cccc(Cl)c2)cc1 +CCOc1ccc(-c2nc(-c3ccc(C(=O)O)cc3)cs2)cc1OCC +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NCC2COCCO2)cc1 +O=C(NC(Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)C(=O)O)c1c(F)cccc1F +Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCC(N3CCCC3)C2)cc1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2ncc3ccccc3n2)C1 +COC(=O)c1c(C(=O)N2CCOCC2)cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1 +CC(=O)c1cc(OCC(F)(F)F)c(=O)n2c1CCC2C(=O)N1CCCC1 +COc1cccc2c1S(=O)(=O)N=C2c1nc(Cc2ccc(F)cc2)c2ccccc2c1O +CC(C)c1cc(-c2ccc(C(N)=O)c(N)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c2n1 +CCCN1CCN(c2nc(CCN(C)C(=O)c3ccc(Cl)cc3)cs2)CC1 +COc1ccc(C2OC34CC(c5ccc(F)cc5)OC(=O)C3=CC2(C)OO4)cc1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccncn2)c1F +O=C1NC(=O)C2=C1c1cn(c3ccccc13)CCOC(CNCc1ccccc1)CCn1cc2c2ccccc21 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+O=[N+]([O-])c1cnc(Sc2nnc(Sc3ncc([N+](=O)[O-])s3)s2)s1 +CC1(C)OCc2c(Nc3n[nH]c4cccc(F)c34)nc(-c3cn[nH]c3)nc21 +CCN1C(=Cc2ccc3ccccc3[n+]2CC)Sc2sc3ccccc3c21 +CC(=O)N1CCN(C(=O)Cc2ccc(C(F)(F)F)cc2)C(CN2CCC(O)C2)C1 +CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(Br)cc1 +CCCCCCNC(=O)Oc1cccc(CN(CCCOc2ccc3c(=O)c4ccccc4oc3c2)C(C)C)c1 +CC(C)CC(=O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NCC2CCOC2)CC1 +c1ccc(CN2CCN(CC3COC4(CCCCC4)O3)CC2)cc1 +COc1ccc(C)cc1S(=O)(=O)n1ccc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 +CCOC(=O)CC(=O)OC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +O=c1oc2ccccc2n1C1CCN(Cc2ccccc2-c2cccnc2)CC1 +CN1CC(=O)N(CC(=O)NC(CC2CCCN(C(=N)N)C2)C(=O)c2nccs2)C(Cc2ccc3ccccc3c2)C1=O +CCC(N)c1ccc(Cl)c(C(=O)c2cccc(O)c2)c1F +CN1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)C2C1CCCC2N1CCC(O)C1 +CC(=O)Nc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +N=C(N)c1cccc(CNC(=O)c2c(Br)c3ccccc3n2Cc2cccc(C(=N)N)c2)c1 +NC(=O)c1cn(-c2ccc(S(N)(=O)=O)cc2)nc1-c1cccs1 +CCCc1ccc(C(=O)NN(C(=O)c2ccccc2Cl)C(C)(C)C)cc1 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+CCCCN(C)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)cc1 +CC(N=C(S)Nc1cc(Br)c(NC(=O)c2ccccc2F)c(Br)c1)c1ccc(F)cc1 +CCNc1cc(N2CCN(C(=O)c3ccc(CC)cc3)CC2)ccc1[N+](=O)[O-] +O=C1C(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1c1ccc(-c2cccnc2)cc1F +Nc1ccccc1NC(=O)CCCCCNC(=O)c1ccc2cn[nH]c2c1 +COS(=O)(=O)c1cccc(-c2ccoc2C2=CN3CCC2CC3)c1 +Cc1ccc(-c2cnc(Nc3cccc4c3CC(O)CC4)o2)cc1 +CNC(=O)C(NC(=O)c1cc(-c2ccccc2)nc2ccccc12)c1ccccc1 +c1ccc2c(c1)C1CC(c3nccs3)(c3nccs3)C2c2cccc[n+]21 +Cn1ncc(NC(=O)c2nc(-c3cc(F)ccc3F)sc2N)c1N1CCC(N)CC(F)(F)C1 +Cc1cc(-c2cn(CCN(C)C(C)C)c(C3CCN(c4ncnc(N)c4C(N)=O)CC3)n2)ccc1F +CCOc1ccc2[nH]nc(-c3cc(N4CCN(C5CC5)CC4)ncn3)c2c1 +CCS(=O)(=O)N1C2CCC1CC1(C2)OOC2(OO1)C1CC3CC(C1)CC2C3 +CCCCN(C)c1cccc(-c2cccc(NC(=O)Nc3ccc(Cl)cc3)c2)n1 +O=C(Cn1c(-c2nccs2)nc2ccccc21)Nc1ccc2ccccc2c1 +COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(C#Cc2cccc(NC(=O)c3cc(C)ccc3F)c2)c1 +CCCOc1ncc(C(C)=O)cc1-c1nc(=O)c2nn(C3CNC3)c(CC)c2[nH]1 +CCS(=O)(=O)c1ccc2c(c1)nc(CC(C)(C)C)n2CC1CC1 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+COc1cc(C=C2CC(C)CC(=Cc3cc(OC)c(OC)c(OC)c3)C2=O)cc(OC)c1OC +COc1cc(F)cc(-c2c[nH]c3ncnc(N4CCCC(O)C4)c23)c1 +CCOc1ccc(CN2CCCC(N3CCN(c4ccc(OC)cc4)CC3)C2)cc1 +CN(C)Cc1ccc(-c2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2)[nH]1 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)C(S)c1ccccc1 +CCCn1c(=O)c2nc(-c3cnn(Cc4noc(-c5cccc(Cl)c5)n4)c3)[nH]c2n(CCC)c1=O +CC(CCOC(=O)NCCCn1ccnc1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +CC1CN(C(=O)c2ccccc2)CCN1c1nnc(-c2ccc(C(N)=O)cc2)c2ccccc12 +Cn1ncc(NC(=O)c2nc(-c3cc(Cl)ccc3F)sc2N)c1C1CCC(N)C(F)CO1 +CCN(C(=O)c1cnn(-c2ccccc2)c1NS(=O)(=O)c1ccc(-c2cnco2)cc1)C1CCCCC1 +CN1CCC(Oc2cccc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)c2)CC1 +CCn1c(C(=O)NCc2cccc(Cl)c2)nc2c(-c3ccccc3)cccc21 +CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccc(I)cc1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cncnc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 +CC1(C)C2CC(CC=CCCCC(=O)O)C(NC(=O)c3ccc[nH]3)C1C2 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)c3ccc(C4CC4)nc3)cc12 +Fc1ccc(CN2CCC(CCNC(c3ccccc3)c3ccccc3)CC2)cc1F +CC1(C)CN=C(N2CCN(c3ncnc4sc(CCF)cc34)CC2)S1 +O=C1C=CC2C(=CC=C(O)O)c3ccc(O)c(O)c3OC2=C1O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ncc(Cl)cc4Cl)nc23)N1 +CCCn1c(=O)c2nc(C3CCC(=O)C3)[nH]c2n(CCc2ccc(N)cc2)c1=O +CC(C)c1cccc(C(C)C)c1NC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC1CCCCC1 +CC(C)C(O)(CC(C)(C)c1ccccc1)C(=O)Nc1ccc2c(c1)COC2=O +CNCCN(c1cc(OC)cc(OC)c1)c1ccc2ncc(-c3cnn(C(C)C)c3)nc2c1 +CC1(C(=O)NNc2cccc3ncccc23)CC2C=CC1C2 +Nc1nc(C(=O)NCP(=O)(O)O)c(-c2cccs2)s1 +Cc1ccc(Oc2ccc(N(CC(NCc3ccncc3)C(=O)NO)S(C)(=O)=O)cc2)cc1 +Clc1ccc2c(NN=Cc3ccc4c(c3)OCO4)ccnc2c1 +COc1ccccc1OCCN1CCN(c2ccc(=O)n(CCN3CCN(c4ccccc4Cl)CC3)n2)CC1 +COc1ccc(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)c(Cl)c1 +CC1=CC2OC3C(O)C4OC(=O)C=CC=CC5OC(CC(C)=CC(=O)OCC2(CC1)C4(C)C31CO1)OC5C +COc1ccc(Cc2cc(C3CCN(C(=O)c4ccc5c(c4)OCO5)CC3)nc(N)n2)cc1 +N=C(NCCC(c1ccccc1)c1ccccc1)SCCCc1c[nH]cn1 +N=c1n(CCN2CCCCC2)c2ccccc2n1CC(O)c1ccc(Cl)c(Cl)c1 +CCc1nc(-c2ccccc2F)c(C(=O)N2CCN(c3cccc(OC)c3)CC2)o1 +CCCCCCCCC(NC(CC)C(=O)N1C(=O)N(Cc2ccccc2)CC1C(=O)O)C(=O)O +CSc1ccccc1N1CCN(CCCCCC(=O)NCc2ccncc2)CC1 +Cc1nc(NC(=O)N2CCN(C3CCCC3)C2=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OC4CCCCC4N(CC)CC)cc3)oc2c1 +COc1cc(-c2cn(C3CCCCN(CC(F)(F)F)C3=O)nn2)ccc1-n1cnc(C)c1 +NS(=O)(=O)c1ccc(C=NCc2ccc(O)cc2)cc1 +COc1cc(OCc2csc(N3CC4CCC(C3)O4)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +COc1ccc(-c2noc(C)c2C(=O)N=C(N)NCc2cc(C)c(NC(=O)C3CC3)c(Cl)c2)cc1 +CN(Cc1ccc(Cl)cc1)C(=O)C1CCOc2ncccc21 +COc1ccc2sc(C(=O)c3cc(OC)c(OC)c(OC)c3)cc2c1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(O)(CN1C(=O)CCC1=O)C2 +CCOC(=O)c1cc2c(n1CC)C(=O)C(Oc1ccc(OC)cc1)=CC2=O +O=C1c2ccccc2S(=O)(=O)N1c1c(F)c(F)nc(F)c1F +N#Cc1c(-c2ccc(F)cc2)c2c(=O)[nH]c(=O)[nH]c2[nH]c1=O +Cc1cc(-c2cccc(F)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +Cc1[nH]c2cc(C3CCCCN3C(=O)c3ccc(F)cc3NS(C)(=O)=O)nn2c(=O)c1C +CC1CN(c2scnc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cc1noc2ccccc12 +CCOc1c(OC)ccc2cc(C(=O)NCCc3ccncc3)c(=O)[nH]c12 +OCc1ccc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)cc1 +CN1CCN(CC(=O)Nc2cc(-n3cccn3)nc(-n3cccn3)n2)CC1 +CN(C)C(=O)Oc1ccc2sc(S(N)(=O)=O)cc2c1 +Cc1cccc(C2CN(C)CCc3c2cc(O)c(O)c3Cl)c1 +CC(C)CC(NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)OCc1ccccc1)B(O)O +Nc1ncc(-c2cc(C3C4CN(C5COC5)CC43)n(C3CCC3)n2)cc1C(F)(F)F +Cc1cc(C)cc(-n2cc(-c3ccccc3)c3c(=O)oc4ccccc4c32)c1 +Clc1cc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c2cc1Cl +CC1CCN(C(=O)c2cccc(Sc3ccccc3Cl)n2)CC1 +CCOc1ccc2nc(NS(=O)(=O)c3ccc4c5c(cccc35)C(=O)N4CC)sc2c1 +CN(c1nc2ccc(NC(=O)CCc3ccc(C(F)(F)F)cc3)cc2[nH]1)C1CCCCC1 +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1)Nc1cc(C2CC2)ccc1F +C#Cc1cccc(-c2nc3ccc(C(F)(F)F)cn3c2NC(C)C)c1 +CCOC(=O)c1sc(Nc2nc(N3CCC(N(C)C)CC3)cc(N3CCNC(C(N)=O)C3)n2)nc1C +O=C(NCc1c(-c2ncco2)n(-c2ccccc2)c2ncccc2c1=O)c1ccc(N2CCC(CO)CC2)nc1 +CCN1C(=O)c2nc(-c3ccc(F)cc3)n(Cc3ccc(F)cc3)c2N2CC(C(C)C)N=C12 +CCN(CC1CC1)C(=O)c1ccc(-c2nc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)cs2)cc1 +CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(CC(C)C#N)c1 +CC(NC(=O)NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)C(=O)O +COc1ccc(Br)cc1-c1nc(CNC2CCN(Cc3ccccc3)CC2)co1 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3C(=O)OC(C)C2CC2)c1C +COC(C)(C)C(O)C(=O)N1CC2CC2C1C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +C=CCN1C(=O)C(=Cc2ccc(O)cc2)SC1=Nc1cccc(C(=O)O)c1 +C#CCn1c(C)c(C(C)(C)C)sc1=NS(=O)(=O)c1ccccc1 +CCC(CC)(CO)COc1cccc2ccc(-c3nnc4ccccn34)nc12 +CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)ccc(C)c1C +COc1ccc(NS(=O)(=O)c2ccc(-c3cccs3)cc2C)cc1N1CC(C)NC(C)C1 +CN(C)c1ccc2c(-c3ccccc3)c3cc4ccc(=[N+](C)C)cc4cc3sc2c1 +CCCc1cnc(-c2ccc(-c3ccc(OCC(C)(C)C(=O)O)cc3)nc2)[nH]1 +NC(=O)c1ccc2[nH]c(-c3ccc(OC4CCC(O)CC4)cc3)nc2c1 +O=C(c1cc(-c2ccc(Cl)cc2Cl)n[nH]1)N(CCO)CCO +CC(NCCc1ccccc1F)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +CN(C)C1=NC2C(CC(C(C)(C)O)C(O)C2O)O1 +Cc1cccc(-c2ccc(OC(C)C)cc2)c1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1C#N +CN(CCN1CCN(c2ccc(F)cc2F)CC1)c1nc(N)n2nc(-c3ccco3)nc2n1 +O=C(NC1CCCCC1)Oc1cccc(-c2cccc([N+](=O)[O-])c2)c1 +COCc1ccc(Oc2cc3[nH]c(-c4ccccn4)nc3cc2C2CCCN2C(C)=O)cn1 +O=C(NCCc1ccc(F)cc1)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +Fc1ccc(-n2cc(C3CCN(CCN4CCN=C4S)CC3)c3ccccc32)cc1 +COc1cc(OCc2csc(C3=CCC(C(=O)OC(C)(C)C)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C1NC(c2ccccc2)(c2ccccc2)CN1C1CCN(Cc2ccccc2)CC1 +NC(=O)C1CCC(CNc2nc(NCc3ccccc3)cc(-c3cccc(C(F)(F)F)c3)n2)CC1 +FC1CNCCCC1Oc1cccc2ccc(-c3nnc4ccccn34)nc12 +CC#CCn1c(N2CCCC(N)C2)nc2ccn(Cc3nc(C)c4ccccc4n3)c2c1=O +CC1CCC(Cn2c(N3CCCC34CCOC4)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +FC(F)(F)Oc1ccc(NC(=S)c2cnoc2C2CC2)cc1 +COc1ccc(C(=O)C=Cc2ccc(O)c(CN3CCN(c4ccnc5cc(Cl)ccc45)CC3)c2)c(OC)c1 +C=CC(=O)N1CCC(Oc2cc3c(Nc4ccc(F)c(Cl)c4F)ncnc3cc2OCCC)CC1 +CCNC(=O)c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F +CN1Cc2cc(C(=O)NCc3c[nH]cn3)ccc2NC(CC(=O)O)C1=O +NC1CN(c2ccc3nnc(C(F)(F)F)n3n2)CCC1c1cc(F)c(F)cc1F +CCCCCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(CF)CC21 +CCOc1ccc(Cc2nc3cc(C(=O)N4CCCCC4)ccc3n2CCC(C)C)cc1 +O=C1Nc2cc(Br)ccc2C1=C1Nc2ccccc2C1=NOCC(O)CO +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCN(c2ccccn2)CC1 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCCN4C(C)CCC4C)cc3)oc2c1 +Cn1c(-c2c[nH]nn2)nc(-c2ccc(F)cc2)c1-c1ccncc1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1ccccc1Br)Oc1ccccc1-3 +CC(Nc1ncc(F)c(N2C(=O)OCC23CCCC3)n1)c1ccc(Oc2ccccc2)cc1 +COc1cccc2cc(CN(CCCCCCNc3c4c(nc5ccccc35)CCCCC4)Cc3cc4cccc(OC)c4o3)oc12 +Cc1nc(C)c2c(n1)N(Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)C(C)C2 +c1coc(-c2nc3nc(NC4CCCCC4)nc(NC4CCCCC4)n3n2)c1 +CN1CCC23c4c5ccc(O)c4OC2c2ncc(-c4ccc(Cl)cc4Cl)cc2CC3C1C5 +CCCc1nc(-c2cccc(C)c2)c(-c2ccnc(NC(=O)c3ccccc3)c2)s1 +CCc1ccc(S(=O)(=O)NCc2ccc(C(=O)NCCN(Cc3ccccc3)C(C)CC)cc2)cc1 +Fc1ccc2nc(Nc3nc(-c4ccccn4)cs3)sc2c1 +N#CCSc1nnc(Cc2c(NC(=O)CCl)sc3c2CCCC3)n1NC(=O)c1ccccc1 +Cc1ccccc1N1CC(C)n2nc(COc3ccc(Cl)cn3)cc2C1=O +CC(C)N(C)C(=O)Cn1c(-c2ccc(Cl)cc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CC(NC1CCN(c2ccc(C(=O)NC(CC(=O)O)C(=O)O)cc2)C1)c1cccc2ccccc12 +CC12CCC3C(CCC4CC(O)CCC43C)C1Cc1snnc12 +CNC(C)C(=O)Nc1ccc(-c2c(-c3cnn(C)c3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1 +CCCOc1ccc(N2CCN(c3noc(CC)n3)C(C)C2)c(C)c1 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+CC(C)COC(=O)N1CCC(CN(C2Cc3cc(C#N)ccc3N(Cc3cncn3C)C2)S(=O)(=O)c2ccccn2)CC1 +CC(O)CNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +CCOC(=O)c1c(C)nc2sc(C(=O)c3ccc(OC)cc3)c(N)c2c1-c1cc(OC)c(OC)c(OC)c1 +O=C(OCC#CCSc1nnc(-c2ccccc2Cl)o1)c1ccc(F)cc1 +CN(C)CCCOc1cccc(-c2n[nH]c3ccc(-c4nnn[nH]4)cc23)c1 +CC(C)Nc1nc(Nc2ccccc2)nc(Nc2ccc(F)cc2)n1 +COCCOc1cc(F)c(N2CCN(Cc3cccc(-c4cc5nc(-c6ccco6)nn5c(N)n4)c3)CC2)c(F)c1 +CN1C(=O)NC(=O)C12Cc1ccc(NC(=O)Cn3c(=O)n4c5c(cccc53)NC(=O)C4)cc1C2 +N#Cc1cc(-c2c[nH]c3ncccc23)cc(NCc2ccccc2)n1 +CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(Cn3ncc4ccccc43)n1CCO2 +COc1ccc(C(=O)C2CCN(C3CN(Cc4cccnc4)CCC3O)CC2)cc1 +CC(C)N1CCN(C(=O)c2ccc(CN3CCCCCC3)cc2)CC1 +Cc1nc2ccccn2c1C(=O)CN1CCN(c2ccc(F)cn2)CC1 +O=C(Nc1ccccc1)c1cccc(Oc2ccc3nccn3n2)c1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CN(S(C)(=O)=O)CC4C3)cc12 +COC(=O)NC(C(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)cc3)ncc12)C(C)C +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)c2cc1OCCN1CCOCC1 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+CCCCNc1cc(NC(C)C(Cc2ccc(Cl)cc2)c2cccc(Br)c2)nc(C(F)(F)F)n1 +Cc1ccc(N2CCOCC2)c(N2CCN(Cc3ccc(F)cc3Cl)C(=O)C2=O)c1 +COc1cc(OC)c2c(c1)OC(c1cc(OC)c(OC)c(OC)c1)C(OC(=O)c1cc(OC)c(OC)c(OC)c1)C2=O +CCOc1cnc2cccc(-c3cc4c([nH]3)CCNC4=O)c2n1 +CC(=O)OC1CCC2(C)C(CCC3C2CCC2(C)C(c4ccc(=O)oc4)C(OC(C)=O)C(O)C32O)C1 +N=C(N)c1ccc2[nH]c(-c3n[nH]c(-c4ccccc4)c3O)nc2c1 +Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCc4ccc(NS(C)(=O)=O)cc4)cc3)c2)o1 +CC(C)(C)NS(=O)(=O)c1ccc(-c2cnc3cccc(Nc4ccccn4)c3c2)cc1 +COCC(O)Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cccc(Cl)c2)n1 +O=C(O)C1C(CC2CCNCC2)C(=O)N1C(=O)N1CCN(C(=O)Cc2ccc3c(c2)CCCC3)CC1 +CC(NC(=O)C1CCNCC1)c1ccc(Nc2ncc3cc(-c4ccncc4)ccc3n2)cc1 +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)CCCCCC(=O)NO)CC2 +Cc1ccc(CN2CC(COC(=O)c3cn(C)c4ccccc34)NC(=O)c3nn(CCc4ccccc4)cc32)cc1 +Cc1cc(OC(F)(F)F)ccc1-c1c(Oc2ccc(C=CC(=O)O)cc2)c2ccc(C(F)F)cc2oc1=O +C=CC(=O)NCCSc1nc(-c2ccc(F)c(C(F)(F)F)c2)c(-c2ccnc(Nc3ccccc3)c2)[nH]1 +CCCc1cc(C(=O)c2ccc(-c3ccccc3)cc2)ccc1OCCCn1ccc2cc(OC(C)(C)C(=O)O)ccc21 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+O=C(CC(=O)N1CCC(Cc2c[nH]cn2)CC1)Nc1cccc(Cl)c1 +O=C(CC12CC3CC(CC(C3)C1)C2)NC1CCC(Oc2ccc(F)cc2)CC1 +CS(=O)(=O)c1ccc(-c2nnn3c2CN(C(=O)CC(N)Cc2cc(F)c(F)cc2F)CC3)cc1 +CCn1nc(Cc2ccccc2)cc1C1CCN(CC2CN(C(C)(C(=O)O)C(C)C)CC2c2cccc(F)c2)CC1 +C#CCN(CCN1CCN(c2ccccc2OC)CC1)C1CCc2nc(N)sc2C1 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccccc3F)CC2)n1 +CCc1nc2c(N(C)C)c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 +CN1CCC(c2cc3c(-c4cccc(NCCCc5ccccc5)n4)ccnc3[nH]2)CC1 +COC(=O)CCc1c(C)[nH]c(C=C2C(=O)Nc3cc(-c4ccc(O)c(OC)c4)ccc32)c1C +O=C(Nc1nc(-c2cccc(Br)c2)cs1)c1ccc(Nc2ccncn2)cc1 +CC(C)(C)C(=O)OCC1(CO)CC(=Cc2ccc(OC(F)(F)F)cc2)C(=O)O1 +Cc1ccc2[nH]c(-n3[nH]c(C)c(Cc4ccc(F)cc4)c3=O)nc2c1 +NC(=NO)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CCNc1nc2sc(-c3cccc(C(C)NC(=O)C4CCN(C)CC4)c3)nc2c2c1ncn2C +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1C(=O)c1ccccc1 +COCCCCn1cnc2cc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c21 +CN1CCC(c2ccc(-c3cc4ncn(C)c(=O)c4c(N4CCC(CO)C4)n3)cc2F)CC1 +CCn1c(=O)c2nc(-c3ccc(N(C)C)cc3)[nH]c2n(CC)c1=O +Cc1cn(-c2ccc3n(c2=O)CCN(CCOc2ccccc2-c2csc(C)n2)C3=O)cn1 +CC(=O)NCCc1ccccc1-c1onc(C2CNCCC2(OCC(O)CO)c2ccc(F)c(F)c2)c1Br +CCOc1ccc(-n2c(C)c3c(C)nnc(N(C)C)c3c2C)cc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2ccon2)CC1 +CCCN(CCN1CCN(c2cccc3ccccc23)CC1)C1CCc2ccc(O)cc2C1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3cccc(F)c3)cc2)cc1)C(=O)O +Fc1ccc(OCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1 +O=C(CN1C(=O)CCc2ncccc21)Nc1scc(Br)c1-c1ncco1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1NC(=O)c1cccc2c(N)nccc12 +CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN(C)C)cc4)c3)cc21 +CC(NS(C)(=O)=O)c1ccc(CN2CCOC(c3cccc(C(F)(F)F)c3)C2)cc1 +CC(=O)N(C)C1CC2CCCCC2C1C=Cc1ccc(-c2cccc(F)c2)cn1 +N=C(N)c1ccc(Cc2ccc(-c3ccc(C(=N)N)nc3)o2)cc1 +CCOC(Cc1ccc2c(ccn2Cc2nc(-c3ccc(F)c(C)c3)oc2C)c1)C(=O)O +O=C(Nc1ccc(Oc2ccncc2-c2cccnc2)c(F)c1)C1=NN(c2ccc(F)c(F)c2)c2ccccc2S1(=O)=O +Cc1ccc(-c2nn(-c3ccc(S(N)(=O)=O)cc3)cc2C(=O)NN)cc1 +CN(CC=Cc1ccc(C(F)(F)F)cc1)Cc1cccc2[nH]ccc12 +c1ccc(C(CCNC2=NCCCCCN2)c2ccccc2)cc1 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+CCCCCCc1cc(O)c2c(c1)OC(C)(C)C1=C2CCN(C)C1 +Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2ncc(Cl)cc2F)s1 +CC(C)c1cccc(C(C)C)c1NC(=O)C1c2ccccc2COc2cc(Br)ccc21 +COc1ccc2nc(NCCCNC(=O)Nc3ccccc3)c3c4ccccc4[nH]c3c2c1 +CC1CN(CC(Cc2ccccc2)C(=O)NC(CCCN)C(=O)O)CCC1(C)c1cccc(O)c1 +O=C(O)c1cccc(-n2cccc2C=C2NC(=O)N(c3ccc(Cl)cc3)C2=O)c1 +O=C(NC(Cc1ccccc1)C(=O)NC(COCc1ccccc1)C(=O)O)C(S)Cc1ccccc1 +CC1CN(CC2CCOCC2)CCN1C(=O)N1Cc2c(NC(=O)c3cn(C)cn3)n[nH]c2C1(C)C +Cc1nn(C2CCOCC2)c2sc(C(=O)NC3CCC(N4CCNC(=O)C4)CC3)cc12 +Cc1cccc(C(=O)N2CCC(O)(c3ccccc3)C3CCCCC32)n1 +COc1nc(C)c(Nc2nc(Cl)cn(C(CCF)C3CC3)c2=O)c(OC)n1 +O=C(NCCNCc1ccc2ccccc2c1)c1ccc2nc(NC(=O)C3CCCCC3)sc2c1 +Cc1cc(OCC2CN(C)c3ccccc3O2)ccc1C(=O)Nc1cccc(CC(=O)O)c1C +COc1cc(Br)ccc1OCCNC(C)Cc1cc(C(N)=O)c2c(ccn2CCCO)c1 +Cc1cc(Oc2cc(NC(=O)C3CC3)ncn2)c(F)cc1NC(=O)Nc1ccc(Cl)c(C(C)(F)F)c1 +COc1cc2nccc(Oc3ccc(NC(=O)Nc4cccc(Cl)c4Cl)cc3)c2cc1OC +CC(C)CC(NC(=O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O)C(=O)O +CCCCOc1ccc2c(c1)C13CCCCC1C(C2)N(C)CC3 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+COc1cc(C(F)(F)F)ccc1-c1cccc2c1C(C)CN(S(=O)(=O)Nc1ncns1)C2 +O=C(O)CNc1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O +CNc1cccc(CCOc2ccc(C3CC3CC(=O)O)cc2)n1 +O=C(c1ccc(O)cc1OCC(O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CC(O)CO1 +CSc1nn2cc(-c3nc4cc(OC(F)(F)F)ccc4o3)nc2s1 +CCOC(=O)COc1cccc2ccc(Cc3cnc(COC)c4cc(OC)c(OC)cc34)nc12 +OCC1OC(Oc2ccc(-c3ccccc3)cc2Cl)C(O)C(O)C1O +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3ccnc4ccccc34)cc2)cc1)C(=O)O +Cc1c(C)n(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 +O=S1(=O)N=C(NC(CCCO)c2ccccc2)OC2CCCCC21 +Cc1cc(Cl)ccc1COc1ccc(S(=O)(=O)N2CCCC(C)(O)C2C(=O)NO)cc1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccccc4C(=O)OCC)c3)nc2n(CCC)c1=O +CC(OCC(N)c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +NCc1cc(F)ccc1CN(Cc1nc2ccccc2[nH]1)C1CCCc2cccnc21 +CCc1ccn2cc(-c3cc(-c4ccccc4)no3)nc2c1 +CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(CO)cc2)c1 +O=C(O)c1nc2ccc(I)cc2c2[nH]c3c(Cl)cccc3c12 +N#Cc1cc(-c2ccnc(N)n2)ccc1OCc1ccc(F)cc1 +CCN(CC)c1nc(Cl)nc(Nc2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)n1 +OC1CCCN(c2cccc(-c3n[nH]c4cnc(-c5cccnc5)cc34)n2)C1 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+CCOC(=O)N1CCCC2C(C=Cc3ccc(-c4cccc(C#N)c4)cn3)C3C(C)OC(=O)C3CC21 +CN(C)C(=O)Nc1ccc(Cn2[nH]c(=O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)cc1 +COc1ccc(C(=O)C=Cc2ccc(C=CC(=O)c3ccc(OC)c(OC)c3)cc2)cc1OC +Cc1cc(NC(=O)Nc2ccc(-c3cc(NC(=O)c4ccc(N5CCN(C)CC5)cc4)[nH]n3)cc2C)no1 +CN(C)CCNc1ccn2ncc(-c3ccc4ccccc4c3)c2n1 +Nc1nc(N)c2nc(CN3c4ccccc4Cc4ccccc43)cnc2n1 +CCCOc1ncc(C(C)=O)cc1-c1nc(O)c2nn(C3CN(C)C3)c(CCC)c2n1 +CCNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2C1OC(C)C(O)C1O +COc1ccc2[nH]c(CN3CCc4ccccc4C3)c(CCNC(C)=O)c2c1 +CCn1c(=O)c2c(nc3ccccn32)n(Cc2ccccc2)c1=O +C(#Cc1ccc(CN2CCCCC2)cc1)CCN1CCOCC1 +Cc1n[nH]c(C)c1CC(=O)NCc1ccc(Cl)cc1Cl +O=C(CCCCCCNC(=O)c1ccc(N(c2cccc(Cl)c2)c2cccc(Cl)c2)cc1)NO +Cc1cc(CN2CCCC2CNc2nc(N)n3nc(-c4ccco4)nc3n2)no1 +O=C(O)C1CCCN(CCC=C(c2sccc2COCc2ccccc2)c2sccc2COCc2ccccc2)C1 +O=C(Nc1cc(-c2c(-c3ccc(F)cc3)nc3n2CCS3)ccn1)c1ccccc1 +COc1cc(C)c2nc3[nH]nc(C)c3c(C(O)c3cncs3)c2c1 +O=C(O)Cc1cc(Br)c(N(Cc2ccc(Oc3ccccc3)cc2)Cc2cccc(F)c2)c(Br)c1 +CC1CN(c2ccc(C(N)=O)cc2)CCN1c1cccc(C(=O)NC2C3CC4CC2CC(O)(C4)C3)n1 +CCC1CN(C2CCN(C(=O)c3ccc4ncccc4c3)CC2)CCC1Cc1ccc(Cl)c(Cl)c1 +CCCCCc1ccc(S(=O)(=O)NCCc2c(-c3ccc(OC)cc3)n[nH]c2CC(C)C)cc1 +c1cc(-c2ccc(OCCCN3CCCCC3)cc2)ccc1CN1CCCCC1 +COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(C#N)c1Cc1ccc(-n2cccn2)cc1 +O=C(NCc1cccnn1)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +N#Cc1cc(C23COC(CF)CC2CSC(N)=N3)c(F)cc1F +CN1CCc2nc(NC(=O)c3cccc(CNC(=O)c4ccc5cc(O)ccc5c4)c3)sc2C1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5ccc(OC)cc5)C4)c3)nc2n(CCC)c1=O +Cc1ncn(C2=NCC(=O)N3CCc4c(cccc4C4CCC4)C3=C2)n1 +CN1CCN(c2nc(N)nc(Cc3ccc(Cl)c(Cl)c3)n2)CC1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccccc3)n(CCN3CCOCC3)c2c1 +O=C(O)COc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +COc1cccc(Cl)c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)cc1 +CCS(=O)(=O)CC(CC1CCCCC1)NCc1ccc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)c1 +COc1ccc(C(Cc2ccccc2)NCC(O)CCc2ccc(O)c(NS(C)(=O)=O)c2)cc1OC +COc1ncccc1-c1cncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1 +CC(=O)OCC(=O)C1C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3=CCC21C +CCCC(NC(C(=O)NO)C(C)O)c1ccc(C#Cc2ccccc2)cc1 +CC(C)C(C)NC1=NS(=O)(=O)c2sc(Cl)cc2N1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(C(=O)NC2CCCCC2)c(Cl)c1 +CCCCCCCC(=O)OCCCC1(CO)CC(=CCC(C(C)C)C(C)C)C(=O)O1 +c1cncc(-c2cc3c(-c4cnn(C5CCNCC5)c4)n[nH]c3cn2)c1 +CS(=O)(=O)CN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21 +Nc1ccc2c(c1)CC(NCC1CCN(CCNS(=O)(=O)c3cccc4ccccc34)CC1)CCC2 +c1csc(-c2ccc3c(-c4cc5cc(CN6CCCCC6)ccc5[nH]4)n[nH]c3c2)n1 +CC[N+](CC)(CC)CCCCCCCC[N+](CC)(CC)CC +Cn1cc(C#N)c2ccc(Nc3ncc(-c4cccc(CN)c4)o3)cc21 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCCC2)CCN(C2CCCC2)C1 +CNc1nc(Nc2ccc(C(=O)N3CCC(O)CC3)cc2OC)ncc1F +CCCOc1sc(C(=O)N2CCC(c3cccc(CN)c3)CC2)c(C)c1Br +COC(=O)c1c[nH]c2cc(CN3CCN(Cc4ccc(OC)cc4)CC3)c(C)cc2c1=O +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)c2cccc(Br)c2)CCC3(O)C1C5 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(SC)cc2)C1O +c1ccc(COCC2CCCCC23OOC2(CCCCC2COCc2ccccc2)OO3)cc1 +Cc1c(F)cc(C(=O)NC2COC2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(CC(=O)O)ccc12 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+CC(C)CCN1C(=O)C(NC(=O)Nc2ccccc2)C(=O)N(Cc2ccccc2)c2ccccc21 +CN(C)CCCNc1nc(NN=Cc2ccc(Cl)cc2)nc2ccccc12 +Nc1ncc(-c2ccc(C3(c4noc(-c5cccc(S(N)(=O)=O)c5)n4)CCC3)cn2)cn1 +O=C(c1cccc(F)c1)N1CCC(F)(F)C(Oc2ccc3ccccc3n2)C1 +CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CN(C(=O)OC(C)(C)C)CC3)cc1 +O=C(NC1CCCCC1)N1CC(Cc2ccccc2)C(c2ccccc2)=N1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cccc(NC(C)=O)c3)ccc2[nH]1 +O=C(NCc1ccc(S(=O)(=O)N2CCN(C3CCOCC3)CC2)cn1)N1Cc2ccncc2C1 +Cc1cn2cc(-c3cccc(O)c3)nc(N3CCOCC3)c2n1 +CN(C(=O)Cc1c[nH]c2ccc(C(=N)N)cc12)c1ccc(-c2ccccc2S(N)(=O)=O)cc1 +O=C(c1ccc(F)cc1F)N1CCn2c(cnc2-c2ccc(F)cc2F)C1 +CC(C)C12OC1C1OC13C1(C)CCC4=C(COC4=O)C1CC1OC13C2(O)CNc1ccc2c(cnn2C)c1 +Fc1cccc(F)c1-c1ccc2[nH]nc(-c3cncc(OC4CCCNC4)n3)c2c1 +Cc1c2c(n3c1CCN(C(=O)CO)CC(C)C(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +CCn1c(C)cc(C=C2NC(=O)N(c3ccccc3)C2=O)c1C +CC1Cc2cccc3c2N1C(=O)C(N1CCN(Cc2ccc(Cl)cc2)CC1)CC3 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1NCC1CCN(C)CC1 +CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cc(F)cc(F)c5)cc34)c(Nc3ccccc3)c2)CC1 +CC(NC(=O)C(=O)c1c[nH]c2ccc(Cl)cc12)c1ccc([N+](=O)[O-])cc1 +COc1cc(N2CCC(N)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 +CC(C)(O)C1CCC(NC(=O)c2cnc(-n3ncc4cc(Cl)cnc43)cc2NC2COC2)CC1 +Cc1ccc(CC2C(c3ccc(C)cc3)CC3CCC2N3C)cc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCN=C(S)Nc4cccc(N=C=S)c4)cc3)[nH]c2n(CCC)c1=O +Cc1n[nH]c(=O)n(CCCN2CCN(c3ccccc3OCC(F)(F)F)CC2)c1=O +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCC(N2CCC(c3ccccc3)CC2)C1 +CN(C)CCCn1cc(NC(=O)c2ccc3cc4n(c3c2)CCCNC4=O)cn1 +O=C(NO)C1Cc2nccnc2CN1S(=O)(=O)c1ccc(Oc2ccncc2)cc1 +NC(=O)c1cc2c(-c3ccc(Br)c(F)c3F)cncc2s1 +COc1ccc2c(c1)CCN(CCCCc1ccccc1)CC2O +CCc1cccc2c(=O)n(C3CN4CCC3CC4)ccc12 +Cc1cnc(N2CC3CCN(C(=O)c4ccccc4-n4nccn4)CC32)cn1 +Cc1c[nH]c(=O)n(CCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O +CC1(C)CC2(CCCN(C3CCN(C(=O)c4c(N)sc5ccccc45)CC3)C2)C(=O)O1 +O=C(NCC#CCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2 +CC(NC(=O)c1ccco1)C(=O)N1CCCN(CCCOc2ccc(-c3noc(C(C)C)n3)c(F)c2)CC1 +COc1ccc2[nH]cc(CCCCN3CC=C(c4ccc5c(c4)OCO5)CC3)c2c1 +Cc1sc(NC(=O)c2ccco2)c(C(c2cccnc2)N2CCC(C)CC2)c1C +CC1=NC2(N=C1N)c1cc(-c3cc(Cl)cc(C#N)c3)ccc1CC21CCC(O)CC1 +Cc1cc(OC(CCC(F)(F)F)c2ccc(C(=O)NCc3nnn[nH]3)cc2)cc(C)c1-c1ccc(C(C)(C)C)cc1 +c1ccc(NCCCCCCCCCCCCNc2c3c(nc4ccccc24)CCCC3)cc1 +Cc1ccc(S(=O)(=O)N2CCNC(=O)C2CC(=O)NC2CCCc3cc(CNC(C)(C)C)ccc32)cc1 +Cc1cccc(N2CCC(C)(c3ccccc3)OC2=O)c1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CNCC(O)C(Cc1ccccc1)NC(=O)C(O)C(F)(F)F +CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C(=O)OC)cc4)cc3)nc2c1=O +CCOc1ccc(C=CCN(C)Cc2cccc3cc[nH]c23)cc1 +Fc1ccccc1Nc1ncnc2ccc(-c3cncs3)cc12 +O=C(NCC1(O)CCCCCC1)c1cc(-c2ccc(CO)cn2)ccc1Cl +O=C(Nc1ccc(Cl)cc1)c1cc(Br)cnc1NCc1ccncc1 +Cn1ccc(COc2ccc3nc(CC4(C(=O)O)CCCC4)n(Cc4ccc(Br)cc4)c3c2)n1 +CC(NC(=O)c1ccc2c(ccn2Cc2ccc(F)cc2F)c1)c1ccc(Br)cc1 +CCC1CC(C(=O)NCC2CCCO2)CN(Cc2nc(-c3ccncn3)[nH]c2C)C1 +O=C(NO)C1c2ccc(O)cc2CCN1S(=O)(=O)c1cc(Cl)ccc1Cl +COc1ccccc1COCCCOc1ccc(N2C(=O)CNCC2COCc2ccc(F)c(C)c2)cc1 +CCN(CC)CCCNc1nc(-c2ccc(NC(=O)Nc3ccccc3Cl)cc2)nc2c(Cl)c(Cl)sc12 +OC1c2ccc(F)cc2CC1N1CCN(c2cc(Cl)cc3c2OCCO3)CC1 +CC(C)C(O)CC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2ccccc2o1 +COc1ccc(-c2nc(C)c(Cl)c(NCC(NC(=O)CCCN3CCNCC3)c3ccccc3)n2)nc1 +CCCN(CCOC)c1nc(C)nc2c1c(C)nn2-c1ccc(OC)nc1C +CCC(=O)NCC1CC1c1cccc2oc(CCCCc3ccccc3)cc12 +Cc1ccc(C(O)(c2ccc(Cl)cc2)c2cncnc2)cc1 +O=C1C(=Nc2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCCN2CCCC2)c1 +Cc1ccc(S(=O)(=O)c2coc(S(N)(=O)=O)c2)cc1 +Cn1ncc(-c2nn(C)c3ncnc(N4CC(F)C4)c23)c1-c1ccc(C(F)(F)F)cc1 +CC(C)NCC(=O)N1CC=CCCOc2cccc(c2)-c2ccnc(n2)Nc2cccc(c2)C1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2ccc(OCc3ccccc3)cc12 +Cc1n[nH]c2cnc(-c3cncc(OCC(N)Cc4ccc(F)c(F)c4F)c3)cc12 +CC(NC(=O)c1ccc(C#Cc2cccc(F)c2)nc1)C(C)(C)O +O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2ccccn2)c1 +Cn1ccc2cc(C(=O)NCCCCCC(=O)Nc3ccccc3N)ccc21 +CC(=O)NC(=Cc1ccco1)C(=O)NC(C(=O)NC(C=C(C)C(=O)O)C(C)C)C(C)(C)C +CCOc1cc(C(c2c(C)n[nH]c2O)c2c(C)n[nH]c2O)ccc1O +Cc1c(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)cccc1C(=O)O +Cc1cccc(Cl)c1Nc1nc2c(N)cccc2n2cncc12 +O=C1c2cc(Cl)cc(Cl)c2OC2c3[nH]c4ccc(O)cc4c3CCN12 +O=C1CC(c2ccccc2)=NCC2(CN3CCC2CC3)N1 +COc1ccc(Cn2c(Nc3ccc(Oc4ncccc4C4CCOCC4)cc3)nc3ccccc32)cc1 +CSc1ccc(-c2cn(C)nc2C2CCC(F)(F)CC2C(=O)NCC#N)cc1 +CC(C)CC(NC(=O)CC(NC(=O)c1ccccc1)c1ccccc1)B(O)O +Cc1c(CC(=O)OCCO)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1cccc(F)c1 +CC(C)C(=O)NCc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2N)cc1 +COc1cccc(-c2ccc(CNC(=O)Nc3cccc(Cl)c3Cl)c3cnccc23)c1 +Cc1c(C2(N(C)C)CCC(c3ccccc3)(N(C)C)CC2)[nH]c2ccccc12 +O=C(CCCCCCc1ccccc1)c1ncc(-c2ccco2)o1 +CCC(N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1)C(C)(O)C(F)(F)F +CC(Cl)(Cl)C(NC(=O)c1ccc(Br)cc1)NC(=NC#N)Nc1ccc(Cl)nc1 +NCCCCC(NC(=O)C(CCC(=O)O)NC(=O)CCc1ccc(-c2ccccc2)cc1)C(N)=O +CC(=O)Nc1nc(C)c(-c2ccc(-n3cccn3)cc2)s1 +Cc1cc(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C3CC3)n2)c(OC(C)C)cc1C1CCNCC1 +CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1-c1ccccc1 +COc1ccc(CNC2CCN(S(=O)(=O)CCC3CCc4ccccc4N3S(=O)(=O)c3ccc(OC)cc3OC)CC2)cc1 +O=C(NCC(=O)N1CCCC1)Nc1ccc2cnc(F)cc2c1 +CCc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3ccnc3)c1)=N2 +N#CSCC1CC(O)(c2ccccc2)C(c2ccccc2)C(c2ccc(Cl)cc2)O1 +O=C(NN=Cc1ccc(-c2ccc([N+](=O)[O-])cc2)o1)C1COc2ccccc2O1 +CC(=O)CCCC(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +Cc1c(C=CCN(C)Cc2ccccc2)nc(O)c2c1ccc1nc(Nc3c(Cl)cccc3Cl)n(C)c12 +CNC(C(=O)NC(C(=O)N(C)C(C=C(C)C(=O)O)C(C)C)C(C)C)C(C)(C)c1cn(C)c2ccccc12 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=NC#N)OC2CCCC2)CC1 +O=C(NC1CCCNC1)c1ccnc2nc(-c3ccc(Cl)cc3)[nH]c12 +N#Cc1c(N)nc(N)nc1NC(CC1CC1)c1nc2cccc(Cl)c2c(=O)n1-c1cccnc1 +OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1ncc[nH]1 +CCCc1ccc(-c2oc(COc3ccc(OCC(=O)O)c(C)c3)nc2-c2ccc(OC)cc2)cc1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)NC(CCCCN)C(N)=O)cc1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCN(C(C)C)CC2)cn1 +COc1ccc(-c2cc(=O)n(CC=Cc3ccccc3)nc2-c2ccc(OC)cc2)cc1 +Cc1ncnc(C)c1OCC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12 +O=S(=O)(c1ccc(C(F)(F)F)nc1)N1C2Cc3[nH]ncc3C1CC(c1ccccc1)C2 +O=C1NCN(c2ccccc2)C12CCN(C1CCc3c(Cl)ccc(Cl)c3C1)CC2 +O=c1[nH]c(C2CCC2c2csc(Cl)n2)nc2c1cnn2C1CCC(F)(F)CC1 +CC(=O)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 +Cc1cccc(NC(=O)Nc2ccc(-c3cncc4[nH]nc(N)c34)cc2)c1 +COCC(C)Oc1ccc2[nH]nc(-c3cc(N4CCOC(C(F)(F)F)C4)ncn3)c2c1 +CNc1nc(Cl)nc2c1ncn2C1OC(C(=O)NCCC(C)C)C(O)C1O +COc1ccccc1N(C)c1cnc2nc(N)nc(N)c2c1 +O=C(O)C(CCCN1C(=O)c2ccccc2C1=O)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 +Cc1c(OCC2CN(C)c3ccccc3O2)ccc(C(=O)n2c(C)c(CC(=O)O)c3ccccc32)c1C +O=C(Nc1cn(CC(=O)N2CC3CN(CC4CCC4)CC3C2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +COCC(N)C(C)Nc1nnc(C(N)=O)c(Nc2cc(C)c3nn(C(C)(C)C)cc3c2)n1 +CCCCc1nc2cc(OC)cc(C(=O)O)c2n1Cc1ccc(N(CC)C(C(=O)O)c2ccccc2)cc1 +CC(=O)N1CCN(c2cccc(-c3cc(-c4ccnn4C4CCOCC4)c4c(N)ncnn34)c2)CC1 +O=C(C=Cc1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCOCC1)NO +O=C(NCC(NS(=O)(=O)c1c(Cl)cccc1Cl)C(=O)O)c1ccccc1 +COc1ccc(CN2CCN(CCOc3ccc(C(=O)NC(=N)N)cc3NC(=O)c3ccc(Cl)cc3Cl)CC2)c(OC)c1OC +O=C(O)c1ccc(Sc2ccc(CN3CCC(N4C(=O)N(C5CCOCC5)CC4c4ccccc4)CC3)cn2)cc1 +Cn1c(-c2ccc(-c3cnc(O)nc3)cc2)nnc1C1(c2ccc(Cl)cc2)CCC1 +O=C(O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c2ccccc12 +c1ccc2c(c1)CCC(CNCCCCNC1=NCCCN1)O2 +O=C(CCN1CCCCC1)NC(Cc1c[nH]c2ccccc12)C(=O)CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CS(=O)(=O)Nc1cccc(C(O)CNCCOc2ccc3c(Cl)n[nH]c3c2)c1 +Cc1ncsc1-c1nnc(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)n1C +c1cn(-c2cncc(-c3cnc(Nc4cc(N5CCOCC5)ccn4)s3)c2)nn1 +CC(C)c1ccc(CCCN2CC=C(CCC(=O)NO)C2=O)cc1 +NS(=O)(=O)c1ccc(NC(=O)CNCCNCC(=O)O)c(I)c1 +CC(C)c1cccc(C(C)C)c1OC(=O)NC(=O)SC1CCCCC1 +COCCN1CCC(Nc2nc(-c3nc4ccccc4n3C(C)c3ccccc3)cn3c(C)nnc23)CC1 +Cc1ccc(-c2ccn(-c3ccc4c(cnn4CCN4CCCC4)c3)c(=O)c2)cc1 +COc1ccc(-c2cccc(CNC(=O)c3ccc4c(c3)OCO4)c2)cc1CN1CCNCC1 +COC1C(=O)N2C(C(=O)OCc3ccc(C(=O)OC(C)(C)C)cc3)=C(COC(C)=O)CS(=O)(=O)C12 +CN1CCCC1Cc1cn(S(=O)(=O)c2ccccc2)c2ccc(Cl)cc12 +O=C(N1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)C1(C(F)(F)F)CCCCC1 +COCCn1cc(-c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)cn1 +CN(C(=O)c1ccc(N(C)C2CCN(c3ncnc4[nH]ccc34)C2)nc1)c1ccccc1 +O=C(O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F +CC(C)c1sc(CO)c(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2sc(CN3CCCC3)cc2c1 +Cc1nnc(N2CCCC2)c2nn(-c3ccc(Cl)cc3OC(F)(F)F)c(C)c12 +Cc1cc(-c2nnn(Cc3ccc(C(=O)O)cc3)n2)cc(C(=O)NCc2ccccc2)n1 +COc1cc(Nc2nc3ccccc3nc2S(=O)(=O)c2ccccc2)cc(OC)c1 +CCCCCCCCCCCCCCCCCCOCCOP(=O)(O)COC(COC)Cn1cnc2c(N)ncnc21 +CC(C)N1CCC(O)(c2cncc(CNc3cc(Cl)c4ncc(C#N)c(Nc5ccc(F)c(Cl)c5)c4c3)c2)CC1 +COC(=O)C1C2CCC(CC1OC(c1ccc(F)cc1)c1ccc(F)cc1)N2 +CCN(CC)CCCCC(CCCCN(CC)CC)Oc1ccnc2cc(Cl)ccc12 +CN1CCN(c2nc3ccccc3c(-c3ccccc3)c2CCO)CC1 +Cc1nc2cc(-n3ncc(C(=O)c4cc5ccc(C6CCN(C)CC6)cc5[nH]4)c3N)ccc2[nH]1 +O=C(NCC(NS(=O)(=O)c1cccnc1)C(=O)O)c1cc2cc(CCC3CCNCC3)sc2s1 +N#Cc1cnn2c(Nc3ccc4c(c3)CCC(=O)N4)cc(N3CCCC3CC(=O)O)nc12 +CCCc1nc(C(=O)NCCCN2CCN(c3cccc(Cl)c3C)CC2)cn1-c1ccc(Cl)cc1 +NC(CCc1ccccc1)C(O)C(=O)NNc1cccc2ccccc12 +Clc1ccc(-c2nc(CNC3CCCC3)cn2-c2ccc(Cl)cc2Cl)cc1 +CC1C(=O)NN=C2COc3cc(F)c(NC4CNC4)cc3N21 +Cc1cccc(-c2c3c(=O)n(C)c(=O)n(C)c3c3n2CC(C)OC3c2ccc(Cl)o2)c1 +CC(C)C#Cc1cccc(C2(c3ccc(OC(F)F)cc3)N=C(N)N(C)C2=O)c1 +[C-]#[N+]c1cc(-c2ccnc(Nc3ccn(C4CCNCC4)n3)c2)ccc1OCC1CC1 +COc1ccc(-n2c(CCc3cn(C(=O)OC(C)(C)C)c4ccccc34)nc3ccccc3c2=O)cc1 +COc1ccc(-c2ccc(C(=O)N3Cc4c(nc5ccccc5c4O)C3c3ccc4c(c3)OCO4)o2)cc1 +CCN(CC)C(=O)C1Sc2c(OC)cccc2-c2c1c1ccccc1n2CCF +CCCn1c(=O)c2nc(C(C3CC3)C3CC3)[nH]c2n(CCC)c1=S +CCCCC(=O)NC1CCCc2c1c1cc(OC)ccc1n2C +N#CC1CC2CC2N1C(=O)C(N)C12CC3CC(CC(F)(C3)C1)C2 +COCCCn1cc(Nc2cc(-c3ccc(OC4CCOCC4)c(C#N)c3)ccn2)cn1 +O=c1c(NCC2CCOCC2)nc2ccc(-c3cnc(O)nc3)nc2n1CC1CCCCC1 +CCCC(=O)Nc1n[nH]c2cc(-c3ccc(O)cc3)c(Br)cc12 +CCCCN(CC)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 +C#Cc1ccc2c(c1)C(=O)N1CCC1c1c(C(=O)OCC)ncn1-2 +CC(NS(=O)(=O)c1ccccc1Cl)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1 +Cc1ccc(Nc2ncc(C(NC(=O)c3nccs3)C(C)C)cc2Cl)cn1 +O=C(C[S+]([O-])C(c1ccc(Br)cc1)c1ccc(Br)cc1)NCCCc1ccccc1 +Cc1ccc(CN2CCC(N3CCC(c4ccc(O)c(F)c4)C(F)C3)C2=O)cc1 +CCc1ccc(-c2nc(C(N)=O)c(-c3ccc(N4CCNC(C)(C)C4)cc3)o2)c2cc[nH]c12 +CCCCS(=O)(=O)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +COc1ccc(C2C(C(=O)O)C(c3ccc4c(c3)OCO4)CN2CC(=O)NC2CCCC2)cc1 +Fc1ccc2[nH]cc(CCCNCCOc3cccc4c3OCC4)c2c1 +O=C(NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1)c1ccc(C(F)(F)F)cc1 +COc1cc(OC2CN(C(=O)c3nnc(-c4ccc(C(F)F)cc4)o3)C2)ccc1CN1CCCC12COC2 +CC(C)CCNC(=O)C(c1cccnc1)N(Cc1ccccc1)C(=O)Cn1nnc2ccccc21 +C=C(CCC12OC(C(=O)O)C(O)(C(=O)O)C(C(=O)O)(O1)C(O)C2O)C(OCC)C(C)Cc1ccccc1 +Cc1nccc2nc(NC3CC3)c(N3CCC(C(F)c4ccc(F)cc4F)CC3)nc12 +c1cc2cc(CCCCc3cc4ccc(C5=NCCN5)cc4o3)oc2cc1C1=NCCN1 +Nc1ccc2c(c1)oc1c(N3CCOCC3)c(F)cc3c(=O)c(C(=O)O)cn2c13 +CC(F)(F)CC(NC(=O)N1CCC2(CCCC2)CC1)C(=O)NC1(C#N)CC1 +NC(=O)c1nn(CC(=O)N2C(C(=O)NCC(F)F)CC3CC32)c2ccccc12 +O=C(Nc1ccccc1C(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC1CCOC1)OCc1ccccn1 +COc1cc(OC)cc(Oc2cnccc2-c2n[nH]c(Nc3ccc4c(c3)OCCO4)n2)c1 +COc1ccc(Cl)cc1Nc1nc(-c2sc(NC(=O)c3ccccc3)nc2C)cs1 +CN(C)CCN1CCN(C(=NS(=O)(=O)c2ccc(Cl)cc2)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)CC1 +COC(=O)Nc1nc2ccc(C(=O)c3ccccc3C(=O)Nc3cccc(I)c3)cc2[nH]1 +Cc1cc(-c2nnc(NCC3OCCO3)o2)nc2c(C(C)(C)C)cc(NCC(F)(F)F)cc12 +Cc1cc(C(C)C)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +Nc1nccn2c(C3CCC4COC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3F)c12 +Cc1c[nH]c2ncnc(N3CCC(O)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12 +CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2C)cc1 +CC(C)C(=O)NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1 +COCC(=O)Nc1ccc2c(-c3cc4ccc(C)cc4[nH]3)n[nH]c2c1 +CSc1cccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(c3ccccc3F)C2=O)c1 +CC(=O)Nc1ccc(-c2ccc(C(O)(c3c[nH]cn3)C(C)C)cc2)cc1 +CC(C)Oc1cccc(Nc2nc3cc(-c4nnn[nH]4)ccc3c3sccc23)c1 +CC(C)C1OC(=O)C1NC(=O)OCc1ccc(-c2ccccc2)cc1 +CC(C(=O)NO)N1CCNc2cc(Oc3cccc([N+](=O)[O-])c3)ccc2S1 +NC(CC(=O)N1CCn2nc(C(F)(F)F)nc2C1C(F)C1CC1)Cc1cc(F)c(F)cc1F +COC12CCC3(CC1C(C)(O)CCC1CCCC1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CCC(c1ccc(Cl)c(Cl)c1)n1c(S)nc(C(N)=O)c1C#N +CN1C(=O)C(NC(=O)c2cc3cc(F)ccc3[nH]2)Cc2ccccc21 +O=C(CC12CC3CC(C1)CC(C1CCCC1)(C3)C2)NN=Cc1ccc([N+](=O)[O-])o1 +Fc1cc(-c2ccccn2)cc(-n2nnc(-c3ccccn3)n2)c1 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2ccc(C(F)(F)F)cc2)cc1 +CCNc1nc(Cl)nc2c1ncn2C12CC(O)C(O)C1C2 +CC#CCNc1ccc(S(=O)(=O)CC2(C(=O)NO)CCCN(S(=O)(=O)C(C)C)C2)cc1 +CNc1cc(-c2cccnc2Nc2c(C)ccc3c(Nc4ccc(Cl)cc4)nccc23)ncn1 +Cc1cc(Oc2cncnc2)cc(C(=O)Nc2cccc(F)n2)n1 +CN1CCc2cc(OCCOCCO)cc3c2C1Cc1ccc(O)c(O)c1-3 +CCC(Cc1ccc(N2CCC(C(=O)NCc3ccccc3C(F)(F)F)CC2)cc1)C(=O)O +CC(C)(C)C(CO)NCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1F +CC(C)(CO)NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +Cc1nc(-c2ccccc2)c(C(=O)N2CCCC(C)C2CNC(=O)c2cccc3cccnc23)s1 +CCC(NC)C(=O)NC1C(=O)N2C(CCC1CCN)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +CC(=O)Nc1nc(C)c(S(=O)(=O)Nc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)s1 +O=C(Cc1ccccc1)NC1CCCc2c1[nH]c1ccc(Br)cc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CN(C(=O)OCCCc2cccnc2)C1 +NC(CC(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O +O=C(c1ccccc1)N1CCOc2ccc(-c3cnc4ccccc4c3)cc2C1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCCc5nc(-n6cnnn6)ccc54)CC3CO2)c1C +O=C(CC1CCN(C(=O)Oc2ccccc2)CC1)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +CCc1c(C)[nH]c(=O)c(N(C)CCOC)c1Cc1cc(C)cc(C)c1 +CCN(CC)C(=O)C1(c2cc3cc(F)ccc3s2)CC1CN +COc1ccc(C=C2N=C(CC(C)C)C(=O)N(O)C2=O)cc1 +CCC(CC)C(=O)C1OC(C(=O)O)=CC(N)C1NC(C)=O +COc1cccc(NC(=O)c2ccc(-c3ccccc3)cc2)c1 +CCOC(=O)C1C2CCC(CC1c1ccc3c(ccn3CC)c1)N2 +Cc1cc(C)c2oc(-c3cc(Br)c(O)c(Br)c3)cc(=O)c2c1 +O=S(=O)(c1ccccc1)c1cc(C(F)(F)F)c2oc3c(c2c1)CNCC3 +Cc1cc(Nc2nn(C(C)C)c(=O)c3cc(CO)ccc23)[nH]n1 +CCCN(CC1CC1)C(=O)c1sc(Nc2c(Cl)cc(Cl)cc2Cl)nc1C +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(C(=O)C2CCCO2)CC1 +CCN(CC)CCOc1ccc(C2Oc3cc(O)ccc3-c3sc4cc(O)ccc4c32)cc1 +COc1cc2ncnc(Nc3cc4ccccc4cn3)c2cc1OC +C=CCN(C(=O)OCc1ccccc1)C1CCN(CCC(C)(c2ccccc2)C2Nc3ccccc3S(=O)(=O)N2)CC1 +CC(C)Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 +CS(=O)(=O)Nc1ccc(OCC(O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2ccccc2O)cc1 +Nc1nccc(Oc2ccc(NC(=O)C3(C(=O)Nc4cccc(F)c4)CC3)cc2F)c1Cl +O=C(C=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cc1)NO +CC1=CC(C)=[N+]2C1=Cc1ccc(C=Cc3ccc(-c4ccc(I)cc4)s3)n1[B-]2(F)F +CC(C)(C)CCN1CCC(CNC(=O)Nc2cccc(Cl)c2)(c2ccccc2)CC1 +Fc1cccnc1ON=C1C=C(C#Cc2ccccn2)CCC1 +O=C(NCc1cccc(F)c1)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CC(NC(=O)c1cccc2c1N(Cc1ccc(-c3ccccc3)cc1)CC2)c1ccc(C(=O)O)cc1 +Nc1ccc(S(=O)(=O)c2cc(Br)nc(N3CCNCC3)c2)cc1 +O=C(COc1cccc2[nH]cc(S(=O)(=O)c3ccc(Cl)cc3Cl)c12)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +O=C1c2ccccc2C(=O)N1CCCCCCCCN1CCN(Cc2ccccc2)CC1 +O=C(NCC1CCN(c2ccc3ccccc3c2)C(=O)C(CCN2CCCCC2)N1)C1=NOC(c2ccc(Cl)cc2)C1 +CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)cn1CCO2)c1ncns1 +CNCC(=O)N1CCN(c2cnc3ccn(S(=O)(=O)c4cccc5nonc45)c3c2)CC1 +CNC(=O)C(CC(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1 +CN(C)CCCNC(=O)c1cc(NC(=O)c2cc(NC(=O)c3cc4ccccc4cn3)cn2C)cn1C +CC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc21 +CC1CCN(CCCC=C(c2ccccc2)c2ccccc2)CC1 +CC12CCCC(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)=C1N(Cc1ccc(Cl)cc1Cl)C(=O)C2 +COc1cc(Nc2cncc(Oc3ccc(NC(C)=O)c4ccccc34)n2)cc(OC)c1OC +COc1cc(OCCN2CCCC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +O=C(Nc1ncccn1)c1oc2cnccc2c1Nc1ccc(Cl)c(O)c1 +COc1ccc(CN(C)CCc2ccc(NC(=O)c3cccc4c(O)c5cccc(C)c5nc34)cc2)cc1OC +CC(=O)NC(C)Cc1ccc(C#Cc2ccc(-n3cccc3)cc2)cc1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(COc2ccc3c(c2)CCCC3)cc1F +CCCCCn1c(=O)n(CC(=O)NC2CCCCC2)c(=O)c2c(C)cccc21 +N#Cc1ccc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)cc1C(F)(F)F +Oc1ccc2c(c1)C13CCN(CC4CCC4)C(C2)C1Cc1c([nH]c2ccccc12)C3 +COCC(C1CC1)n1nc(C)nc(Nc2c(Cl)cc(OC(F)(F)F)cc2Cl)c1=O +Nc1ncc(-c2ccc(-c3ccccc3Oc3nccc(C(F)(F)F)n3)cc2F)cn1 +CC(C)N1CCN(c2cccc3nc(CN(C)C4CCCc5cccnc54)cn23)CC1 +Cc1[nH]c2ccccc2c1CCN(CCF)Cc1ccc(C=CC(=O)NO)cc1 +CCOC(=O)CSc1ccc(C(=O)Nc2ccc(OC)cc2)cn1 +OC(CNCC1CCCO1)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21 +COc1ccc2sc(S(=O)(=O)NC3CCN(Cc4cc(C(=N)N)ccc4N)C3=O)cc2n1 +CC(=O)Nc1nc(C)c(-c2csc(NCCc3n[nH]c(=O)o3)n2)s1 +CC1C=CC=C1C(=O)N1CCN(C(=O)NC2CCN(c3ccc(C(=O)N4CCCC4)cc3)CC2)CC1 +NC(=O)c1ccc(CNC(=O)NCC2CN(Cc3ccc(Cl)c(Cl)c3)CCO2)cc1 +COCCCOc1cc(C(=O)N(CC2CNCC2OCc2cccc(-c3ccccc3OC)c2)C(C)C)ccc1OC +Cc1cc(SC2=C(O)OC(CCc3ccccc3)(c3ccccc3)CC2=O)c(C(C)(C)C)cc1N +COc1ccccc1NCCCCCCNCCCCCCCCNCCCCCCNc1ccccc1OC +CC12CCC3C(CCC4=CC(=O)NCCC43C)C1=CC=C2c1cncc(F)c1 +COc1cc2c(N3CCN(C(S)=NCc4csc(C)n4)CC3)ncnc2cc1OCCCN1CCCCC1 +N=C(NCCCC(N)CNc1ccccc1CCN)N[N+](=O)[O-] +CCCS(=O)(=O)NC1CNCC1CN(C(=O)c1ccc(OC)c(OCCCOC)c1)C(C)C +CC(=NOC(CO)CO)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +CN1C2CCC1C1COC(=O)CCCCCCCCC(=O)Nc3ccc(cc3)C1C2 +CC(C)c1onc(CSc2nnnn2C)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +O=C(Nc1ccc(C2CCN(C(=O)C3CCOC3)CC2)cc1)N1Cc2ccncc2C1 +Cc1nc(-c2ccccc2)oc1CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +CC(C)n1cc(-c2cnc3[nH]cc(-c4cc(C(C)(O)c5ccccc5)nc(N)n4)c3c2)cn1 +CN(c1ccccc1)c1ccc2cc(-c3n[nH]c4ccccc34)[nH]c2c1 +Cc1cc(COc2ccc(C(=O)NCC3(C)NC(=O)NC3=O)cc2)c2ccccc2n1 +O=C(CN1CCC(c2ccccn2)CC1)Nc1c(Cl)cc(Cl)cc1Cl +CC(C)=CCc1cc(C(=O)Nc2cc3ccc(OCCCN(C)C(C)(C)C)c(C)c3oc2=O)ccc1O +COc1ccc(Cl)cc1N1CCN(CCn2cnc3sc4c(c3c2=O)CCN(C)C4)CC1 +O=S1(=O)N=C(Nc2ccccc2F)Nc2c(O)cc(Cl)cc21 +c1cc2c3cnc(Nc4ccc(N5CCNCC5)cn4)nc3n(C34CC5CC(CC(C5)C3)C4)c2cn1 +CC1C2Cc3ccc(C(N)=O)c([N+](=O)[O-])c3C1(C)CCN2CC1CC1 +COc1cc(C=C[N+](=O)[O-])c(C=Cc2ccccc2)c(OC)c1OC +N#Cc1ccc(NC(=O)COc2cccc(C(=O)Nc3nc4c(s3)CC(N3CCN(C5CC5)CC3)CC4)c2)cc1 +Fc1ccc(-n2ncc3c(-c4cncc5ccccc45)ccnc32)cc1 +CN1C2=NC3C=CC=CC3C2=C(NCCCO)c2ccccc21 +CCCCN(CC)c1nc(C)nc2c1ncn2-c1c(Cl)cc(OC)cc1OC +COc1ccc(F)cc1-c1cc(NC(=O)C2CCCNC2)ncn1 +Cc1nc2nc(C(=O)NC3CCN(C(C)C)CC3)cn2c(-c2ccc(Cl)cc2Cl)c1CN +CCC1CC(=O)NN=C1c1ccc2nc(-c3cccc(OCc4cccnc4)c3)oc2c1 +Cn1c(=O)c2c(nc(COc3ccc(Br)cc3)n2C)n(C)c1=O +O=S(=O)(NCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(O)c1 +CC(C)CC(CO)NC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +CCn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(Cl)cc4)cc3=O)cc21 +CC(C)NC(=O)Nc1ccc2c(c1)C(=O)N(C(C)CO)CC(C)C(CN(C)S(=O)(=O)c1ccc(Cl)cc1)O2 +O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCNC2)c1O)Nc1cccc(F)c1Cl +COc1ccc(S(=O)(=O)N2CCC(NCC(O)COc3ccc(O)cc3)CC2)cc1 +CCOc1ccnc(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(C)(N)CC3)n2)c1F 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+CN(C(=O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccncc2)CC1 +CN(O)C(=O)CC(CCCCc1ccccc1)CP(=O)(O)O +O=C(Nc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccccc1)OCc1ccc(Cl)cc1 +CN(CC(=O)Nc1cccc(S(N)(=O)=O)c1)C(=N)N +COc1cc(O)c2c(c1)oc(=O)c1c3cc(O)c(O)cc3oc21 +O=C(O)CN1C(=O)C2(CC(=O)N(Cc3nnc(C4CC4)s3)C2=O)c2cc(Cl)ccc21 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3ccccc3)nc21 +O=C(CCCCCN1C(=O)c2ccc(I)cc2S1(=O)=O)NO +Cc1noc(C2CC3CSC(N)=NC3(c3ccc(F)cc3F)CO2)n1 +CCCCNC(=O)NS(=O)(=O)c1ccc(OCc2no[n+]([O-])c2-c2ccccc2)cc1 +COC(=O)c1ccc(-c2cc(=O)c3ccccc3o2)cc1 +O=C(NCc1ccco1)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 +OCc1cccc(C(O)CNCc2ccccc2OCc2ccccc2)c1 +CC(C)NC(=O)C1CCC(n2c(=NC(=O)c3ccc(F)cc3)[nH]c3ccc(CN4CCCCC4C(=O)O)cc32)CC1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(CCc1cccc(Oc3ccc(C)cc3)c1)CC2 +CCCCCCCCCCCC(c1ccc(Cl)cc1)c1c(O)c2ccccc2oc1=O +C=C(C)C1CCC(C)=CC1c1c(O)cc(CCCCC)cc1O +Fc1cnc(Nc2ccc(N3CCOCC3)cc2)cc1-c1ccn(CCN2CCOCC2)n1 +Cn1nc(C(N)=O)cc1Nc1nccc(-c2ccc(N3CCCC3)c(C#N)c2)n1 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+CN1CCN(c2ccc(NC(=O)c3c(NCCc4ccc(Cl)cc4)cc[nH]c3=O)cc2)CC1 +Cc1cc(C(=O)Nc2cn3nc(-c4cn(C)nc4-c4ccc(F)cc4)ccc3n2)ccn1 +CN(C)CCOc1cc(-c2cn[nH]c2)c(F)cc1NC(=O)C1Cc2ccccc2CN1C(=O)CN(C)C +CC(C)NC(=O)C(F)CNc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +CC(C)(Cc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)NCCCCC2CCCCC2)co1)C(=O)O +Cn1c2c(c3cc(Cl)ccc31)CN(CCCOc1ccc(F)cc1)CC2 +CCCC(Sc1nc(N)c2cnn(-c3ccccc3)c2n1)C(N)=O +COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc([N+](=O)[O-])c(F)c(C)c2Cl)c1 +O=C(NCCc1ccccn1)C(c1cn[nH]c1)N1CCN(c2ccc(Cl)c(Cl)c2)CC1 +Cc1cc(-c2cnn(CCC(=O)O)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CCOCc1cc2cnc(Nc3ccc(N4CCOCC4)cn3)nc2n(C2CCCC2)c1=O +CCOC(=O)C(Oc1ccc2c(c1)CN(C(=N)N)CC2)c1ccc(OC2CCNC2)cc1 +Cc1ncc(C)n2nc(-c3ccn4cc(C5CC5)nc4c3)nc12 +CCN1CCCC1CNC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +CC(c1ccccc1)N(C)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 +O=C(NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(C2CCCCC2Cn2cncn2)CC1)C1Cc2ccccc2CN1 +COc1cc(C(=O)NCCc2cccc(C(F)(F)F)c2)ccc1-c1cn[nH]c1 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+COc1cccc2c1ncc1c(=O)n(-c3cccc(Cl)c3)c(=O)n(C3CCN(S(=O)(=O)c4ccccc4)CC3)c12 +CNCCCN1c2ccccc2N(c2ccccc2F)S1(=O)=O +CC(C)CN(CC(O)C(Cc1cccnc1)NC(=O)OCc1cncs1)C(=O)c1ccc2ncsc2c1 +CCC(C(=O)NC(CC(=O)O)C(=O)CNCN1CCC(Cc2ccccc2)CC1)n1ccnc(NCc2nonc2C)c1=O +CC1CN(C(=O)c2nc(Nc3cc(C4CC4)[nH]n3)c3cc(Cl)ccc3n2)CC(C)N1 +CN(C)CCCCn1cnc2c(O)nc(Nc3ccccc3)nc21 +O=S(=O)(Nc1ncns1)c1ccc2c(-c3ccc(C(F)(F)F)cc3O)nccc2c1 +CS(=O)(=O)CCCOc1ccc(-c2cc(F)cc(C3COc4cc5c(cc4O3)OCC5CC(=O)O)c2)c(Cl)c1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(CO)(Cc5ccccc5F)C4)cc23)ccn1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2Cl)CC1 +CC(NC(=O)C=Cc1ccccc1F)c1cccc(Oc2cccnc2)c1 +COc1cc(-c2ncoc2-c2ccc(OC)c3c2ncn3CCCO)cc(OC)c1OC +CC(N)c1ccc(-c2c(O)cc(Br)c3[nH]c(=O)c4sccc4c23)cc1 +Cc1ncc(CN2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccnc(F)c4)n3)CC2)s1 +CN1CCN(c2ccc(-c3nc(Cl)c4c(n3)N(CCCN3CCCC3)CC4)cc2)CC1 +COc1cc(Cn2c(N)nc3cc(-c4cnn(C)c4)cnc32)ccc1OCc1csc(C(F)(F)F)n1 +Cc1ncc2c(-c3ncc4c(n3)NC(=O)C4(C)C)nn(Cc3cccc(F)c3F)c2n1 +Cc1ccc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)nn1 +O=C(O)c1ccn(Cc2cc(Br)ccc2OCc2ccccc2)n1 +N=C(N)NC(=O)c1ccc(C2CCN(C(=O)c3ccccn3)CC2)c(C(F)(F)F)c1 +CCOC(=O)c1c[nH]c2ncnc(-c3cccc(NC(=O)C4(C)CO4)c3)c12 +O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1cc2ccccc2cn1 +CN1C(=O)C(=O)c2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)cc3)cc21 +COc1nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)nc(N2CCCC2C(N)=O)n1 +NC(=O)c1cc(N(CCBr)CCBr)c([N+](=O)[O-])cc1[N+](=O)[O-] +CC(Nc1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)c1cccc2ccccc12 +CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2nnccc2N)cc1 +O=C(O)C1CCC(NC(=O)C2(CS)CCc3ccccc3C2)CC1 +Cc1cc(C)nc(NS(=O)(=O)c2ccc(N=Cc3c(Cl)c4ccccc4oc3=O)cc2)n1 +Cc1nn(Cc2ccccc2-c2cc3ccc(Cl)cc3[nH]2)c(C)c1CC(=O)O +O=c1c(C2=NS(=O)(=O)c3cc(OCn4cnnn4)ccc3N2)c(O)c2cc(F)ccc2n1CCC1CC1 +CCc1ccc(C(=O)C(=O)N2C3CCCC2C2c4c(cc(OC)cc4OC)CCN2C3=O)cc1 +COc1cccc(C(=CC#N)c2ccc(OC)c(OC)c2)c1 +Cc1nc2cc3c(cc2n1-c1ccccc1)C1CNCC3C1 +O=C(NCc1ccncc1)c1cnc(Oc2ccc3c(c2)CCC(c2cccc(F)c2)O3)s1 +Fc1ccc(C2(c3ccc(F)cc3)CNC(c3cnccn3)=N2)cc1 +Cc1ccc(-c2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)cc1 +CC(C)S(=O)(=O)c1cc(C#Cc2cc(Cl)ccc2OCC(=O)O)ccc1C(=O)N(C)C +O=C(O)C(CC1CC1)N1CC(CN2CCC(CCCc3ccccc3)CC2)C(c2ccccc2)C1 +FC(F)(F)c1cccc(-c2ncccc2CC(c2cccnc2)c2cccnc2)c1 +Nc1cccc(S(=O)(=O)NC(=O)c2c(-c3ccc[nH]c3=O)c3cc(Cl)ccc3n2Cc2ccnc(N)c2)c1 +CC(Cc1ccccc1)(Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1)C(=O)O +CCCCCN(C(=O)c1cccc([N+](=O)[O-])c1)C(CC)c1nc2ccccc2c(=O)n1-c1ccccc1OC +CC(C)(CNCCCc1ccccc1)CNCCOC(c1ccccc1)c1ccccc1 +CC(Nc1ccc(F)cc1)c1cc(C(=O)NCCN(C)C)cn2c(=O)cc(N3CCOCC3)nc12 +N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)nc2)cn1 +O=C(Cc1ccccc1)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +Cc1onc(-c2ccccc2Cl)c1C(=O)N(C)c1cc(Br)c(C)c(Br)c1 +Cc1cc(=O)n2nc(-c3ccccc3)n(Cc3ccccc3Cl)c2n1 +CCOc1ccc(-n2c(C)c3c(C)nnc(Nc4ccc5c(c4)CCC5)c3c2C)cc1 +CC1CCCN1CCc1ccc(-c2ccc(S(=O)(=O)Cc3ccccc3)cc2)cc1 +CN1C(c2nc(CC(=O)O)cs2)C(c2cccc(Cl)c2F)C2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2 +O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(Cl)cc1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3-c3ccccc3)ccc21 +CCOc1ccc(C(C)Nc2nc(N3CCN(C(C)=O)CC3)nc3c2CN(C(C)C)C3=O)cc1F +Nc1cccc(CN2C(=O)N(Cc3ccc4ccccc4c3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)c1 +Cc1nnn(-c2ccc(F)cc2)c1COc1cc(C(=O)NC2(C)COC2)n(C)n1 +O=C(c1ccc([N+](=O)[O-])cc1)C1CCN(CCc2ccccc2)CC1 +NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)cc1 +Cc1cccc(N2CCN(CC(O)CNC(=O)c3nc(C)n(-c4ccccc4)c3C)CC2)c1C +O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccccn1)c1ccc(F)cc1 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3Cl)nc12)N1CCC(O)CC1 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)OCCO3)cc1 +CC(=O)c1ccc2c(c1)N(CCCN1CCN(CCO)CC1)c1ccccc1S2 +COC(=O)c1ccc(Oc2ccc3c(c2)COB3O)nc1 +O=C1CC(c2c(Cl)ccc(N3CCOCC3)c2Cl)CC(O)=C1Sc1ccccc1Cl +Cc1cc(-c2nc(C3CCCCN3C(=O)COc3ccccc3)no2)n(C)n1 +O=C(NCc1ccc(C(F)(F)F)nc1)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +NC(=O)c1c(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)[nH]c2ccccc12 +O=C(OCC1CCCC(c2cc(F)cc(F)c2)N1S(=O)(=O)c1ccc(Cl)cc1)N1CCN(C2CCCCC2)CC1 +C=CCN(C)CC=CCOc1ccc2c(-c3ccc(Br)cc3)noc2c1 +COc1ccc(C2c3nc(NC(C)C)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)c(CCO)c1 +Cc1cc(C#N)cnc1C(=O)Nc1ccc(F)c(C2(C)COC(C)(C(F)(F)F)C(N)=N2)c1 +CC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3cnn(-c4ccccc4)c3n2)cc1 +COc1ccc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 +COc1cc(CC(=O)NCCCc2ccc(C)c(C)c2)ccc1O +CCNC(=O)Nc1nc2cc(-c3ccc(C)nc3)c(OCC3CCOC3)nc2s1 +N#CC(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1NC2CCC1C2 +C#CC1(O)CCC2C3CCC4=Cc5oncc5CC4(C)C3CCC21C +OCC(O)CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +CCN(C)C(=O)Cn1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +CCOc1cc(NC(=O)CCCCCNC(=O)C(N)Cc2ccccc2)cc2c1OCC([N+](=O)[O-])=C2 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(c4ccccn4)CC3)c(C(F)F)c21 +COc1ccc(Cn2nncc2-c2cc(OC)c(OC)c(OC)c2)cc1N +O=C(Cc1cn(Cc2ccc(F)cc2)c2ccc(Cl)cc12)Nc1ccncc1 +CCC1OC(c2ccc(Cl)c(Cc3cnc(-c4ccoc4)nc3)c2)C(O)C(O)C1O +Oc1ccc(-c2ccc3c(-c4ccccc4)c(O)ccc3c2)cc1 +O=C(O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)NCCCCc2ccc(F)cc2)co1 +CN1CC(COc2ccc(C(=O)N(C)c3cccc(CC(=O)O)c3)cc2)Oc2ccccc21 +CC(C)c1ccc(CC(C)(C)NCC(O)c2cc(O)cc3c2OCC(=O)N3)cc1 +Cc1c(C(=O)NC2CCOCC2)cc(-c2cc(C(C)(C)C)c3c(c2)C2(CCO3)CC2)n1CC1CCCCC1 +Cc1ccc(N2CCc3ncnc(NC(C)c4ccc(Cl)cc4)c3C2)nc1 +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)c2cccc(C(F)(F)F)c2)CCC3(O)C1C5 +CCc1nc(Cn2nnc3c(N)nc(C4CC4)nc32)cs1 +O=C(NCC1CCN(c2nsc(Cc3ccc(F)cc3)n2)CC1)Nc1ccc(Cl)c(Cl)c1 +CC(NC(=O)C(=O)Nc1cccnc1N(C)C)C(=O)NC(CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F +COC(=O)NC(C)CNc1nccc(-c2nc(C3CC3)[nH]c2-c2cc(Cl)cc(NS(C)(=O)=O)c2Cl)n1 +Cc1ccc(CNC(=O)C2SC(n3cnc4c(NCc5cccc(I)c5)ncnc43)C(O)C2O)cc1 +CCCCc1nc(-n2cccc2)c(C(=O)O)n1Cc1ccc(NC(=O)C(Cc2ccccc2)n2cccc2C(=O)O)cc1 +CC(C)(C)c1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 +O=C(NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5)c1ccncn1 +CCc1cn(C2CC(O)C(CNC(=O)C3c4ccccc4Cc4ccccc43)O2)c(=O)[nH]c1=O +COc1ccccc1OCCNCC1COCC(c2ccccc2)(c2ccccc2)O1 +Cn1c(CN2CCN(c3nc(Cl)ccc3C(F)(F)F)CC2)nc2cc(C#N)ccc21 +NC(=O)C(c1ccccc1)C1CCCCN1Cc1ccccc1 +COc1ccccc1Cn1c(N2CCCC(N)C2)nc2c3cc(C(=O)O)ccc3n(C)c(=O)c21 +Cc1c(C)c2ccc(OCc3ccc(CN(C)Cc4ccc(C#N)cc4)cc3)cc2oc1=O +CCOC(=O)c1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccn3)c2c1 +Cc1c(-c2cc(Nc3cc4n(n3)CCN(C)C4)c(=O)[nH]n2)cccc1N1CCn2c(cc3c2CCCC3)C1=O +O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1ccc(F)cc1 +CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(C(F)(F)F)n1C1CC2C1 +CC(C)(C)C1(O)CCN(CC2c3ccccc3CCc3cc(Cl)ccc32)CC1 +CNCCN(C)c1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(C#N)cc12 +CCOC(C)CNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CC(C)Oc1ccc2c(c1)C(c1ccc3c(c1)OCO3)=C(C(=O)O)C(c1ccc3c(c1)OCO3)O2 +COc1ccc2c(c1)CCc1c-2c2c(c3c4ccccc4n(CCCO)c13)CNC2=O +CN1C(CC(=O)c2ccccc2)CCCC1CC(OS(=O)(=O)Cc1ccccc1)c1ccccc1 +COc1cc(C=C[N+](=O)[O-])c(C=Cc2ccc(Cl)cc2)c(OC)c1OC +Cc1cnc(NC(C)C)nc1-c1ccc2c(c1)CCC(C)N2C(=O)c1ccc(O)cc1O +CC(C)Cc1ccc(N2CCc3cc(O)ccc3C2(C)c2ccc(C=CC(=O)O)cc2)c(F)c1 +Cc1cccc(OC(CC2CNC2)c2ccc(Cl)c(F)c2)c1 +CC(NC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OCc1cccc(N)c1)c1ccccc1 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCCN4CCSCC4)cc3)oc2c1 +CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2-c2noc(O)n2)cc1 +Cc1oc(C2CC2)nc1CC(=O)Nc1cncc(C(=O)c2cn(C(C)C)c3ccncc23)c1 +Cc1ccc(C(=O)N2CC(F)(c3ccc(C#N)cc3)C2)cc1-c1[nH]nc(Cl)c1C +O=C(NC1CC1)c1cc2c(s1)-c1ccccc1N(C(=O)c1ccc(NC(=O)c3cccnc3N3CCOCC3)cc1)CC2 +COc1ccccc1C1C(C(=O)C2(CO)CCCCC2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +Cc1c(C(=O)NC(C)(C)c2cn3ccsc3n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(CCCCCCNC(=O)c1ccc(C(CO)(c2ccccc2)c2ccccc2)cc1)NO +CCOc1ccc(CC(NC(=O)c2ccc(C)cc2)C(=O)NC(Cc2cscn2)C(=O)NCc2ccc(CN)cc2)cc1 +CN1CCC2(CCN(c3cc(NC(=O)N4CCCc5ccc(C=O)nc54)ncc3C#N)CC2)C1 +CN(CCN1CCCCC1)C(=O)N1CCN(c2cccc(Cl)c2)CC1 +CCOCCn1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc43)cc2)c2c(C(=O)OC)cccc21 +CC1(C(F)F)CC(NC(=O)Nc2ccc3c(c2)NC(=O)CC3)c2ccccc2O1 +COc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2n1 +O=C(C(O)c1ccccc1)N1CCC2CC21C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +CN1C2COCC1CC(NC(=O)c1cn(CC(F)F)c3ccc(F)cc13)C2 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC1(C)C +CC(C)C(CC(N)=O)NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1 +CC(C)(O)Cn1cc(-c2ccc3c(c2)OCCc2sc(-c4ncnn4CC(F)(F)F)nc2-3)cn1 +N#Cc1ncccc1CSc1nc(O)c(C#N)c2c1CCCC2 +Cc1ccc(-c2noc(C3(N(C)C)CC3)n2)cc1NC(=O)c1cnc2ccccn12 +Cc1ccc(S(=O)(=O)NC(=O)c2ccc(Cl)cc2Cl)cc1 +CCCC(=O)C1(c2ccccc2)CCN(C(=O)c2ccc3[nH]ccc3c2)CC1 +CC(C)(C)c1ccc2c(c1Cl)CCN2C(=O)Nc1cccnc1 +Cc1nc(C(F)(F)F)ccc1Cn1c(=O)c(-c2ccncc2)c(-c2ccc(Cl)cc2)c2nn(C)c(=O)n21 +CC(C)c1nc2c(c(Nc3ccc(C(F)(F)F)c(Cl)n3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +Cc1ncc(-c2ccc(Nc3cc4cc(-c5cnn(CC(C)(C)O)c5)ccc4cn3)cc2)n1C +O=c1cc(N2CCOCC2)c2ccc(-c3cccs3)cc2o1 +Cc1cc(NC(=O)N2CC=C(c3ncc(-c4nc(CO)no4)cc3Cl)CC2)ccc1C(F)(F)F +CC(=O)Nc1cc(-c2ccccc2)c(-c2nnc(S)n2N)s1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCNC(CO)CO)CCCC1)c1cc2ccccc2s1 +C=C(Br)C(=O)Nc1cccc(C=C2SC(=O)N(Cc3ccccc3)C2=O)c1 +CC(Oc1ccc2[nH]nc(-c3nc4ccccc4s3)c2c1)c1c(Cl)cncc1Cl +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2N(C)C)N2C1=NC1CCCC12 +O=C(Nc1ccc2cn[nH]c2c1)c1cnc(N2CCOCC2)c(Cl)c1 +N#Cc1cc2ccc(N3CCOCC3)cc2n2c1nc1ccccc12 +O=C1C(=Cc2ccc(F)cc2)CNCC1=Cc1ccc(F)cc1 +CC(C)c1cc(Nc2ccnc(NCc3cc(-c4ccccc4)no3)n2)[nH]n1 +CC(O)(COc1ccccc1C(F)(F)F)C(=O)N1CCc2c(C#N)cccc21 +Cn1nc(S(N)(=O)=O)sc1=NCc1cc(=O)oc2cc(Cl)ccc12 +CC(C)(CNC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1)N1CCOCC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N4CCCC4(C)C)ncc3F)C2)cc1 +CCCCC(NC(=O)OC(C(C)C)C(C)C)C(=O)C(=O)NC(C)c1ccccc1 +CC(C(=O)Nc1ccc(-c2ncc[nH]2)cc1)n1ccc(-c2cc(Cl)ccc2C#N)cc1=O +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(CC3CCN(C(=O)OC(C)(C)C)CC3)C2=O)cc1 +CC(=O)N1Cc2ccc(NC(=O)c3ccccc3)cc2CCc2ccccc21 +N#Cc1c(-c2cc(C(F)(F)F)ccc2Cl)cc(-c2cc(Cl)ccc2O)[nH]c1=O +N=C(N)c1ccc(OCc2ccc([N+](=O)[O-])cc2)c(I)c1 +Cc1nnc2c3ccccc3c(-c3ccc(N4CCOCC4)c(NS(=O)(=O)c4ccccc4Cl)c3)nn12 +O=C(c1ccc(F)cc1)C1CCN(C2CN(C(=O)c3ccccc3)CCC2O)CC1 +Cc1ccnc(NC(=O)c2ccc3cc4n(c3n2)CCCNC4=O)c1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(NC3CCOCC3)cc(-c3ccccc3)n2)CC1 +O=S(=O)(NCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2ccccc2c1 +NC(=O)c1sc(-c2cnn3ccccc23)cc1OCc1ccccc1C(F)(F)F +CN(C1CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)C1)S(C)(=O)=O +CC(NC1=NC(=O)C(C)(C(C)C)O1)c1ccccc1 +CC(C)COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +COc1cccc(C2CCOP(=O)(COc3cc(C)c(C)c4c3-c3ncsc3C4)O2)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1nc(-c2ccc(F)cc2)no1 +CN(C)C(=O)c1sc2ncnc(N3C4CCC3CC(N(C)C3CCC3)C4)c2c1-c1ccccc1 +CCc1cc(OC)c(C(=O)Nc2cccc3c2CCN(C)C3)cc1Cl +CC(C)CC(NC(=O)c1ccc(NCc2c[nH]cn2)cc1-c1ccccc1)C(=O)O +CCn1c(CN2CCN(Cc3ccccc3)CC2)nc2cc(NC(=O)c3cccs3)ccc21 +Cc1ccc2c(c1CCC(=O)C(C)(C)O)C(=O)C(=O)C(C(C)C)=C2 +O=S(=O)(Nc1cccc(OCCNc2ccncc2)c1)c1ccc(F)cc1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1ccccc1OCC(F)(F)F +COc1cc(C(=O)c2cn(Cc3ccccc3)c(-c3ccc(C)cc3)n2)cc(OC)c1OC +C=Cc1cc(-c2ccc(O)cc2)nc2ccc(O)cc12 +CNC(=O)c1cn2ncnc(Nc3cc(NC(=O)c4cc(F)cc(N5CCOCC5)c4)ccc3C)c2c1C +COc1ccc2c(ccn2CCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)c1 +Cc1nc2ccccc2n1Cc1ccc(C(=O)NC2CN(C(=O)OC(C)(C)C)CC2C(=O)NO)cc1 +O=C(OC1CCNC1)C(O)(c1ccccc1)c1ccccc1 +NC(=O)C1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1 +COc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 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+O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(-c3cnccn3)cnc2C1 +COC(=O)C1C(c2ccc(I)cc2)CC2CCC1N2CCF +CC(Oc1cc(-c2cnoc2)cnc1N)c1c(Cl)ccc(F)c1Cl +CCCCNC(=O)C(C)CC(O)C1CSCCCCSCC(NC(C)=O)C(=O)NC(C)C(=O)N1 +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NC(CO)C(O)c1ccccc1 +O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +O=c1ccc(Cc2cc(Oc3cccc(Cl)c3)c3occc3c2)n[nH]1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2Cc3[nH]ncc3C1CC(c1ccccc1)C2 +CC(=O)NC(C)c1ccc(OC2CCN(c3nccc(OCC4CC4)c3F)C2)cc1 +O=c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)nn1-c1ccc(F)c(Cl)c1 +CCOC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +CC(C)N(C)C1CCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)CC1CS(=O)(=O)c1ccccc1 +Cc1nc(-c2ccccn2)nc(N2CCC(Cc3ccccc3)C2)c1Cl +OC12C3C4CC5C6C4C1C6C(C53)N2Cc1ccccc1F +NC(=O)c1cccc(-c2c(-c3ccccc3)oc(=O)c3c2nn2c(-c4ccccc4)ccnc32)c1 +Cn1cc(-c2cnc3ccc4ccc(NS(=O)(=O)N5CCOCC5)cc4c(=O)c3c2)cn1 +Cc1ccccc1C(=CCCN1CCCC(C(=O)O)C1)c1ccccc1 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)CNCc4cccc(OC)c4)cc13)N(C)S(=O)(=O)CC2 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+CC(=O)NC1C(NC(=N)NC(=O)Cn2cc(-c3ccccc3N)nn2)C=C(C(=O)O)OC1C(O)C(O)CO +CC(C)(C)SCC(=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O +Cc1cc(Nc2nc(Cl)cn(C(COC(=O)Nc3ccccc3)C3CC3)c2=O)c(C)nc1OC(F)F +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C(C)CNCc1cccc2[nH]ncc12 +O=C1CCC2c3c(-c4noc(C5CC5)n4)ncn3-c3ccccc3N12 +COc1cc(OC)cc(N(CC(O)CN2CCOCC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C1CCc2cc(C(c3ccco3)n3ccnc3)cc3c2N1CC3 +N#Cc1ccc(-c2ccc(OCCCN3CCC(N)C3)cc2)cc1 +CC(C)(Cc1ccc2ccccc2c1)NCC(O)COc1ccc(CCC(=O)O)cc1C#N +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)cc1OP(=O)(O)OC +O=C(CCCCC(=O)N1CC=CCCOc2cccc(c2)-c2ccnc(n2)Nc2cccc(c2)C1)NO +CCN(CCn1cc(-c2ccc(F)c(C)c2)nc1C1CCN(c2ncnc(N)c2C#N)CC1)C(C)C +CC(=O)NCC1CN(c2ccc3c(c2)CCCc2c(NCCN)n[nH]c2-3)C(=O)O1 +Nc1ncnc2c1ncn2C1OC(CNC(=O)CCCCCCC(=O)Nc2cccc3c2CNC3=O)C(O)C1O +CN(C)CCC=C1c2ccccc2COc2ccc(CC(=O)O)cc21 +COCCOCc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +CCc1cc(C(C)=O)c(O)cc1OCCCOc1cccc(Oc2ccccc2C(=O)O)c1 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+O=C(OCC(C1CCCCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 +CC1(C)OC2=C(C(=O)C(=O)c3ccccc32)C1OC1CCCCC1 +CNC(=O)c1cc(Oc2ccc3nc(NC(=O)c4cc(C(F)(F)F)cc(C(F)(F)F)c4)sc3c2)ccn1 +COc1ccccc1C(C)NC(=O)c1ccc(Sc2ccc(N)cc2)c(Nc2ncnc3nc(C(C)C)ccc23)c1 +CCCCc1cc2c(=O)c(CC)c(C)[nH]c2cc1OCCOc1ccccc1 +Cc1nc(-c2nc(-c3ccc4cc(CCN5CCCC5C)ccc4n3)cs2)cs1 +O=C1C(=Cc2ccccc2)CC2(O)C3Cc4ccc(O)c5c4C2(CCN3CCCc2ccccc2)C1O5 +CN(C)c1ccc(CNC(COCc2ccccc2)C(=O)N2CCC3(CC2)CN(S(C)(=O)=O)c2ccccc23)cc1 +COc1ccc(-c2ccc(C#Cc3cccc(C#Cc4ccc(-c5ccc(OC)cc5)cc4)[n+]3C)cc2)cc1 +O=C(O)CN1CN(Cc2ccc(C(F)(F)F)cc2)S(=O)(=O)c2cc(Br)ccc21 +CCN(CC)CCn1ccc2cc(-c3ccc(Oc4ccc(F)cc4)cc3)ccc21 +O=C(c1ccc(-c2ccc(O)c(Cl)c2)cc1)c1ccc(F)c(O)c1 +Cc1cccc2c(NCCCN(C)C)c3c([N+](=O)[O-])ccc(C)c3nc12 +CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCCCOC)c2sccc23)cc1 +O=C1CCc2cc(Nc3cc(C(F)(F)F)ccn3)ccc2N1 +COc1ccc(S(=O)(=O)N2c3ccccc3CCC2CCS(=O)(=O)N2CCC(NCC3CCOCC3)CC2)c(OC)c1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(CO)c1ccc(F)c(F)c1 +Cc1cc(C)n(-c2nc(Nc3ccccn3)cc(N3CCc4ccccc4C3)n2)n1 +O=C(CCC1CCCC1)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)CC1CCCCC1 +NC(=O)c1cccc(-c2ccc3c(C=O)c(O)ccc3c2)c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)N5CCC(F)(F)CC5)s4)nc23)N1 +NC(=O)C(Cc1ccccc1)NC(=O)C(CS)NC(=O)c1ccc2c(c1)OCO2 +Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C(F)(F)F)ccc3o2)cc1 +COc1cc2cc(-c3ccccc3)n(Cc3cccc(C(=O)O)n3)c2cc1C +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(CC(=O)N(C)C4CC(O)C4)CC3)cc12 +Cc1ccc(C(=O)NC2(C)COC2)cc1-c1ccc2cc(NC(=O)C3CC3F)ncc2c1 +CC12CCC3c4ccc(C(=O)NC5CCCC5C(=O)O)cc4CCC3C1CC=C2c1cncc(F)c1 +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cn(C)nc3C)nc12 +Cc1nc(COc2ccc(C(=O)Nc3cc(NC(=O)c4cc(F)cc(N5CCOCC5)c4)ccc3C)cc2)cs1 +CC(C)c1nc(-c2cccnc2)c(-c2ccc(F)cc2)n1C=CC(O)CC(O)CC(=O)O +COc1ccc(Cc2nnc(C3(C)CCc4c(C)c(O)c(C)c(C)c4O3)o2)cc1OC +O=[N+]([O-])c1cc(O)c2c(c1)S(=O)(=O)N=C(Nc1ccccc1Br)N2 +NC1=NC(=O)C(=C2CCNC(=O)c3[nH]c4c(Br)csc4c32)N1 +Cn1c(-c2ccccn2)c(C2CCCC2)c2ccc(C(=O)NC3(C(=O)Nc4ccc(C=CC(=O)O)cc4)CCC3)cc21 +COc1cccc2c1nc(N)n1nc(CN3CCN(c4ccc(F)cn4)CC3C)nc21 +Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1c(F)cc(O)cc1F +COc1cc(C=CC(=O)OCCCCO[N+](=O)[O-])ccc1OCCCCO[N+](=O)[O-] +N=C1NC(c2ccccc2)(c2cccc(OCc3ccccc3)c2)C(=O)N1C1CCCCC1 +COC(=O)c1cc2occc2n1CC(=O)c1cccc(Br)c1 +COc1ccccc1CNc1ncc(C#Cc2ccc(CC(C)NC(C)=O)cc2)cn1 +N=C(N)c1ccc(C2C3C(=O)N(Cc4cccc(F)c4)C(=O)C3C3CCCN32)cc1 +CC(C)S(=O)(=O)NCC1CCC(NCCN2CCCc3cc(Cl)ccc32)CC1 +CCC1C(C)=NN=C(c2ccc(OC)c(OC)c2)c2cc(OC)c(OC)cc21 +CC1CN(c2ccc(Nc3ncc4c5ccccc5n(C5CCCC5)c4n3)nn2)CCN1 +CC(C)NC(=O)c1nc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cc(N)c1C#N +CC1(c2cccc3ccccc23)C(=O)N(CCCn2ccnc2)C(=O)N1Cc1ccc(CN)cc1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1cccc(CO)c1 +CN(C1CCC1)C(C)(C)c1nc2c(C(N)=O)cccc2[nH]1 +N#Cc1c(-c2ccc(NC(=O)CCCC(=O)O)cc2)cc(-c2ccccc2O)nc1N +CCNC(=O)c1cc(C(N)=O)nn1-c1cccc(-c2ccccc2OC(F)(F)F)c1 +CNc1nccc(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)n1 +Cc1ncc(C)n2nc(CCc3nc(N4CCC(C(F)F)C4)nn3C)nc12 +CCCCCNC(=O)C(=O)C(Cc1ccccc1)NC(=O)C1Cc2cc3c(cc2S(=O)(=O)N1CC)OCCO3 +COc1ccnc(-c2ccnc(Nc3ccc4c(c3)CN(CCN3CCN(C)C3=O)C4)n2)c1 +COc1ccc(C2c3cc(OC)c(OC)cc3C(=O)C(C)C2C)cc1OC +Cc1cc(OCCN2CCN(c3ccccc3)CC2)nn1-c1ccc(Cl)c(Cl)c1 +CCOC(=O)c1cncc(N2CCC(C(N)Cc3cc(F)ccc3F)CC2)c1 +CCn1c(NC2CCCC2)nc2c(C#Cc3cccnc3)csc2c1=O +CC1(C)CC=C(c2cc(C(C)(C)N3CCCCC3)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +CCN(CC)CCn1c(CC(C)(C)C)nc2cc(C=CC(=O)NO)ccc21 +O=C(Nc1nc(-c2ccc(F)cc2)cs1)C(Cc1cnc[nH]1)NC(=O)C1OC1C(=O)O +CCN(CC)Cc1c(C)nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n12 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Cc3ccccc3)cc2F)CC1 +Cc1cccc(F)c1S(=O)(=O)NC1(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)CC1 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCCCC1 +CC1(O)CCCN(S(=O)(=O)c2ccc(OCc3cccc(Cl)c3)cc2)C1C(=O)NO +Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc3ccccc13)cc(=O)n2C +Oc1cc(NCCCNCc2cc(Cl)cc(Cl)c2Cl)nc2ccccc12 +COc1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 +O=c1cc(-c2ccc(Cl)cc2)oc2cc(OCCN3CCN(c4ccccc4)CC3)ccc12 +NC(=S)NN=C(c1cc(Br)cc(C(=O)c2ccccc2F)c1)c1ccccc1F +COc1cc(Nc2nc(NC3CCCCC3N)n3nc(C)nc3c2C(N)=O)cc(OC)c1 +Nc1nc(NCCc2cc(Br)cs2)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1ccc(NS(=O)(=O)c2cccc3ccccc23)c(O)c1CC(=O)NCc1ccc(C(=N)N)cc1 +COc1cc(Cc2cnc(N)nc2N)cc(C#Cc2ccc(C(=O)O)cc2)c1OC +CCN(Cc1c(Cl)cncc1Cl)C(=O)CN1CCN(c2ccnc(NCCc3ccc(Cl)cc3)n2)CC1 +O=C(NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1)c1ccccc1 +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cn(C)nc3C)cc12 +CC(=O)NCC1CN(c2ccc(-c3ccc(CNCc4ccco4)cc3)c(F)c2)C(=O)O1 +CCCCCCCCCCCCCC=CCC(O)C(O)C(N)(CO)C(=O)O +CC(=O)c1cc(F)c(Br)cc1NCC(=O)Nc1ccccc1C(=O)O +Cc1cc(N(C)CCO)nc2ccc(NC(=O)C=Cc3ccc(OC(F)(F)F)cc3)cc12 +Cc1c2c(=O)n(C)[nH]c2cc(=O)n1Cc1ccccn1 +CC(=CCC12OC(C)(C)C3CC(C=C4C(=O)c5c(O)cccc5OC431)C2=O)COC(=O)c1cccnc1 +CN(CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)CO +CS(=O)(=O)c1cccc(-c2cc(N3CCC(c4cc(F)c(F)cc4F)C(N)C3)ncn2)c1 +COc1ccc(N(C)c2nc(C)nc3c(Cc4ccccc4)cn(C)c23)cc1 +CCOC(=N)c1ccc(-c2ccc3cc(CCN4CCCC4C)ccc3n2)s1 +Fc1ccc(OC(c2ccc(F)cc2)C2CCNCC2)cc1 +Fc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cn1 +O=C(O)CCCN1CC(C(=O)O)Oc2c(NC(=O)c3ccc(OCCCCCc4ccccc4)cc3)cccc21 +CC(=NOCc1ccc(-c2ccccc2F)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cc1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nc(-c2ccccc2)oc1Cl +O=C(C=Cc1cccn1Cc1cc(F)ccc1F)CC(=O)C(=O)O +CN1C(=O)CCC1(C)C(=O)NCc1ccc(Cl)cc1Cl +COc1ccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cn2)c(F)c1 +CC(CO)NC(=O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(Cc2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCC(c1cccc(NS(=O)(=O)c2ccc(C#N)cc2)c1)c1c(O)c2c(oc1=O)CCCCCC2 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)CCN1CCCCC1 +O=C(O)c1nc2c(O)nc3cc([N+](=O)[O-])c(-n4cccc4)cc3n2n1 +CC(=O)Nn1c(Cc2csc(NC(=O)CCl)n2)nnc1SCC(=O)NNC(=O)c1ccccc1 +CC1(c2cc(CNCC(F)(F)F)c(F)cc2F)CCSC(N)=N1 +Cc1cccc(NC(=O)NC(CCC(=O)N2CCCC2)C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(-c3ccccc3)c2c1 +CCN(C)c1nc2ccc(C(=O)N(CC(C)C)CC(O)C(Cc3ccccc3)NC(=O)OCc3ccncc3)cc2o1 +COCCn1cc(C2CCN(Cc3ccc(OC)c(C(=O)O)c3)CC2)c2ccc(F)cc21 +COc1ccc(C(=CC=CC(=O)NC(C)CCCc2cccnc2)c2ccccc2)cc1 +Cn1c(=O)n(C2CCOCC2)c2c3nc(-c4cc[nH]n4)ccc3ncc21 +CN(C)c1nn2c(-c3ccccc3)nnc2c2ccccc12 +CN1CCc2cc3c(c4c2C1Cc1ccccc1-4)OCO3 +COc1cccc2c1CCC1CN(CCCn3c(=O)[nH]c4c(sc5ccccc54)c3=O)CC21 +[N-]=[N+]=Nc1cccc(CCN2CCN(c3cccc(C(F)(F)F)c3)CC2)c1 +O=S(=O)(Nc1ccc2nccc(N3CCNCC3)c2c1)c1ccc(I)cc1 +CC(C)c1ccc(S(=O)(=O)NC(=O)C(c2ccc3c(c2)OCO3)c2c[nH]c3cc(C(=O)O)ccc23)cc1 +O=c1[nH]c(CCc2ccccc2)cc(Oc2ccccc2)c1I +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(Cl)cc1 +CC(C(c1ccc2cc(OCc3cccc(C(N)=O)c3)ccc2c1)n1ccnc1)N(C)C +O=C(COc1ccncc1)N1CCCCC1c1nnc(-c2cccc(C(F)(F)F)c2)[nH]1 +CN(C)c1ccc(Nc2ncc(Br)c(Nc3ccccc3)n2)cc1 +CC(c1ccc(-c2ccc(F)cc2)cc1)N1CCC(CCCO)(c2ccccc2)OC1=O +CC1OC(n2cc(-c3ccccc3)c3c(NCC(S)=NC4CC4)ncnc32)C(O)C1O +COc1ccn2c(c1)nc1c2c(=O)n(CCC(C)(C)C)c(=O)n1Cc1ccccc1 +CN1CCN(CCNc2cc(-n3ccnc3Nc3cc(Nc4ccc(OC(F)(F)F)cc4)ncn3)cc(C(F)(F)F)c2)CC1 +C=CCOC(=O)C1(C)CCC2(C)CCC3(C)C4=CC=C5C(=CC(=O)C(O)=C5C)C4(C)CCC3(C)C2C1 +Cc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CN(C)C1=O +CN(C)Cc1ccn2c(-c3ccnc(NCc4c(F)cccc4F)n3)c(-c3ccc(F)cc3)nc2c1 +Cc1cc(N2CCN(CCc3ccc4c(c3)NC(=O)CO4)CC2)c2ccc(C)nc2c1 +CC(C)(C)NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1 +O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc(-c4ccoc4)n3)ccc1-2 +O=C(C=Cc1ccc(Cl)cc1)NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCCN2CCC=N2)N1 +Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(C(F)(F)F)c2)c(=O)c2ccncc21 +N=C(N)NCCCC(NC(=O)CCN1c2ccccc2Sc2ccccc21)C(=O)NC(Cc1ccccc1)C(N)=O +CCOC(=O)N1CCC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +CC(N)=NC(=NS(=O)(=O)c1ccc(F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +O=C(O)c1c(Cc2cc3c(cc2Cl)OCO3)c(-c2ccccc2)nn1CC1CCC(C(=O)O)CC1 +Brc1cccc(Nc2ncnc3cnc(NCCc4ccccn4)cc23)c1 +CCCn1c2ccc(C(C)=NOC)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +O=C(NCC1CC1)N(Cc1ccccc1)Cc1cccc(C#Cc2ccccc2)c1 +CCC(C)C(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccc(CCC(=O)OC)cc2)cc1 +c1ccc(COc2ccc(CNCCCCCCCCCCNCc3ccc(OCc4ccccc4)cc3)cc2)cc1 +Fc1ccc(CC(Nc2nc3cc(F)c(F)cc3o2)c2ccccn2)cc1 +CCc1c2s[nH]c(=O)c2c(=O)n2ccc(-c3cc(C)nc(C)c3)cc12 +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCc1ccccc1 +O=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1cccc(CCc2ccccc2)c1 +CC(C)(C)ONC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O +O=C(O)c1nc2c(O)nc3cc(C(F)(F)F)c(-n4ccnc4)cc3n2n1 +CC(=O)c1ccc2c(c1)C(NC(=O)c1ccc(F)cc1Cl)C(O)C(C)(C)O2 +Clc1ccc(N2CCN(CCc3cc4ccccc4o3)CC2)cc1 +CC(C)c1nnc2ccc(-c3ocnc3-c3cccc(Cl)c3)cn12 +CN(C(COCc1ccccc1)C(=O)NC(C=O)Cc1ccccc1)S(C)(=O)=O +COc1cc(C2C(C#N)=C(N)Oc3c2ccc(N)c3N)cc(Br)c1OC +CCP(=O)(O)C(C(=O)NC=Cc1ccc(F)c(F)c1)c1csc2ccc(Cl)cc12 +Cc1c(-c2nnc(C3(c4ccc(Cl)cc4)CC3)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1cc(Cc2nc3n(n2)Cc2c(C)ncn2-c2ccc(Br)cc2-3)on1 +Cc1cccc(NC(=O)NCC=C(c2ccccc2)c2ccccc2)c1 +COc1cc(C=CC(=O)NCCCCNc2c3c(nc4ccccc24)CCCC3)ccc1OCCCCCCO[N+](=O)[O-] +COc1ccc(Nc2nc(Cl)cn(C(C)C3CC3)c2=O)c(OC)n1 +COc1ccc2c(=O)c(C(=O)NC3CCCCC3)cn(CCN3CCOCC3)c2c1 +CC(N)CNc1nc(-c2cn[nH]c2)nc2sc3c(c12)CCCC3 +CC(C)c1cc(Nc2ccc(C#N)c(Cl)c2)ncc1C(=O)NCC1CCOCC1 +CC1(F)C(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)OC1n1ccc(=O)[nH]c1=O +O=C1c2c(nnn2Cc2ccc3ncccc3c2)CCN1c1ccccc1 +Cc1csc(Nc2ncc(Sc3ccccc3)cc2OCc2ccccc2)n1 +COC(=O)NC1CCN(c2cc(C#N)cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)c2Cl)CC1F +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4ccncc4)o3)cc2Cl)CS1(=O)=O +COc1ccccc1-c1cn2c(-c3ccc(Cl)cc3)c(CN)c(C)nc2n1 +Cc1cc(C)n2nc(CSc3nc(-c4ccccc4)cn3C)nc2c1 +N=C(NC(=N)N1CCN(C(=N)NC(=N)Nc2ccc(Br)cc2)CC1)Nc1ccc(Br)cc1 +CC(C)(C)C(=O)C(=O)N1CCCC1C(=O)OCCCc1ccccc1 +O=C(C(=O)N1CCN(C(=O)c2ccno2)CC1)c1c[nH]c2cccc(F)c12 +O=c1[nH]c2ccccc2n1CCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +COC1Cc2ccccc2C1Nc1ncnc(NC2CC(O)C(COS(N)(=O)=O)C2)n1 +COc1ccccc1N1CCN(CCC(Oc2ccc(NC(=O)c3ccccc3OCCCC(=O)O)cc2)c2ccc(C)cc2)CC1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(CC(=O)NCCO)c4ccccc43)CC2)C(C)C)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)F)n1)c1cc(F)c(-c2cnn(C)c2)cc1F +O=C(O)c1c[nH]c2cc(F)c(-c3ccc(OCCC4CCOC4)cc3)c(F)c12 +NS(=O)(=O)Nc1ccc(NC(=O)NC2CCCCC2)cc1 +COc1cc2nc(SCC(C)C)n(CCCn3ccnc3)c(=N)c2cc1OC +O=C(c1cnccn1)N1CCN(CCCNc2nnc(-c3ccccc3)c3c2cc2ccccn23)CC1 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+COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 +Cc1ncc(Cl)cc1C(=O)NC1CCC(CN2C(=O)C3(CC3)c3cc(F)ccc32)CC1 +Cc1cc(O)c(-c2ccc(C(CN)C(C)C)cc2)c2c1[nH]c(=O)c1sccc12 +CS(=O)(=O)C(C(=O)NCCS(=O)(=O)c1ccc(F)cc1)c1nc2ccc(-c3ccnc(F)c3)cc2s1 +CC1(C)CC=C(c2cc(C3CC4(CO)CCC(CO)(C3)O4)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +CN(C)CCNC(=O)c1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +COC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)ccn2)c1 +Cc1cccc(-c2oc(C)nc2C(=O)Nc2cnn(Cc3nc(C4(O)CC4)co3)n2)c1 +COc1cc(OC)cc(C(=O)N2CCC(N3CC(CC#N)(n4cc(-c5ncnc6[nH]ccc56)cn4)C3)CC2)c1 +Cc1c(C(=O)Nc2ccc(S(=O)(=O)N(C)C3CCN(C)CC3)cc2)oc2c(Cl)cccc12 +Cc1cccc(C(=O)N2CCC(N3CCC(Cc4ccc(C(=O)NC(C)C)cc4)CC3)CC2)c1N +COc1cc2ncnc(C#CC(C)(O)Cc3ccccc3)c2cc1OC +CC(NC(=O)c1cnn(C)c1N)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 +CCC=CCOC(C)C1=CC(C)(C)Nc2ccc(-c3ccccc3OC)cc21 +CCOc1ccc2c(c1)cc(C(=O)NCCCCCC(=O)Nc1ccccc1N)n2C +Cc1ccc(CCCC(CP(=O)(O)O)C(=O)NC(CC2CCCCC2)C(=O)NCCc2ccccc2)cc1 +Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CC[N+](C)([O-])CC4)ccc3OC(F)(F)F)ncc1CC2 +COc1cc(Cl)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CCCCCCCCCCC(=O)C1CCC(C2CCC(C(=O)CCCCC(=O)CCCCCCCC3=CC(C)OC3=O)O2)O1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(OCC)cc1 +CN1CCC(c2cc3c(-c4nc(NCc5ccccc5)ccc4Cl)ccnc3[nH]2)CC1 +CCC(c1ccc2c(c1)CCO2)N(Cc1ccc(OCCN2C(=O)CN(C)C2=O)c(OC)c1)CC1CCC(C(=O)O)CC1 +CCc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +N#Cc1ccc2[nH]c(-c3ccc(F)cc3)c(CCCC(=O)NS(=O)(=O)c3ccccc3)c2c1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2cccnc2)CC1 +CCC1(c2cccs2)OCC(=O)Nc2ccc(-c3ccc(F)c(Cl)c3)cc21 +O=C(Nc1ncc(F)s1)C(CC1CCOCC1)n1ncc2c(S(=O)(=O)C3CC3)cccc21 +COc1c(OCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)cc(C)nc1C +CNC(=O)c1cc(-c2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 +CC(C)(Oc1ccc(S(C)(=O)=O)cc1)C1OCC(CC=CCCC(=O)O)C(c2cccnc2)O1 +COc1ccc(-c2nc3c(c(Nc4ccc(CC(=O)O)cc4)n2)SCCC3)c(F)c1F +O=C(NC1CC1)c1ccc2c(=O)n(C(CC3CCCCC3)C(=O)Nc3ncc(Cl)s3)cnc2c1 +N#Cc1cccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)c1 +CCOC(=O)C(CC)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2nc(OCCCN3CCCCC3)cc2c1=O +CC(=O)OCC1C2CCC(C)C1(C)CCC(C)=CCCC1(C)OC1C2=O +Cc1nc(C)c(C(=O)N2CCc3cc4ccnc(N5CCN(C)CC5)c4cc32)o1 +CC(=O)Oc1c2c(c3ccccc3c1OC(C)=O)OC(C)(C)C=C2 +CNc1nc(C2CC(F)(F)CN2C(=O)C(O)C(O)C(=O)NC(C)c2ccc(-n3cccn3)cc2)cs1 +COc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2cc1OCCCCCn1ccnc1[N+](=O)[O-] +[Li]OC(=O)c1ccc(C(C)NC(=O)C2CCCN2Cc2ccc(C(F)(F)F)cc2)cc1 +Cc1cn(C2CCCN(C(C)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3)C2)c(=O)[nH]c1=O +Fc1ccccc1C1CCN(Cc2ccn3c(CC4CC4)nnc3c2C(F)(F)F)CC1 +NC(CNC(=O)Nc1cccc(S(=O)(=O)O)c1)C(=O)O +N#CC1CCCCC1n1cc(C(N)=O)c(Nc2ccc(OC(F)F)cc2)n1 +COC(=O)c1ccc(CSc2nc3ccccc3c(=O)n2-c2ccccc2)o1 +O=S(=O)(NCCCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc2ncccc2c1 +CN1CCN(c2ccc(OCc3ccccc3)c(NCc3ccco3)c2)CC1 +CN(C)CCCn1c(SCC(=O)N2c3ccccc3Sc3ccccc32)nc2ccccc2c1=O +COc1ccc2nc(C(C)C)c(C=CC3CC(O)CC(=O)O3)c(-c3ccc(F)cc3)c2c1 +CC(C)N(c1cccc(N2CCN(C)CC2)c1)S(=O)(=O)c1cccc2ccccc12 +CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)nc(CNC)cc21 +CC1(C)CN(c2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)c2c(O)ccc(-c3cc(F)cc(F)c3)c21 +NC1=NC(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)(C(F)(F)F)C2CC2O1 +CC#Cc1cncc(-c2cc(Cl)c(C3(C)CC(c4c(C)noc4C)SC(N)=N3)s2)c1 +CCC(C)NC(=O)c1nc(-c2cccc(F)c2)cnc1N +O=C(NC1CCC(Cn2ccc(N3CCNC3=O)n2)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1cccc(C(=O)N2CC3CC(Nc4ccc(C(F)(F)F)cn4)C2C3)c1-n1nccn1 +CCOC(=O)Cc1ccc(OC(=O)CCCNC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 +O=C(c1ccc(CO)cc1Cl)c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12 +CC(C)CC(NC(=O)c1cc2ccccc2o1)C(=O)NC1CCC(C)N(S(=O)(=O)c2ccccn2)CC1=O +CC(F)(F)c1cccc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c1 +CC(C)CS(=O)(=O)c1nc(C(=O)N2COCC2(C)C)ccc1C1CC1 +COc1cccc(C(=O)NCc2nnc(S)n2-c2ccc(Cl)c(Cl)c2)c1 +CNC(C)C(=O)Nc1ccc2c(n1)OC1(CCCC1)C(=O)N2c1ccc(Cl)cc1 +Cc1nnsc1C1=NNC(=O)C1=Cc1cn(C)c2cccc(Br)c12 +CC(C)CC(NC(=O)C(=Cc1ccccc1)CN1CCC(C)(c2cccc(O)c2)C(C)C1)C(=O)O +CC(C)CC(O)c1ccccc1N1CCN(C(=O)C(N)Cc2ccc(Cl)cc2Cl)CC1 +N=C(N)NCCCC(=O)NCCc1ccc(S(N)(=O)=O)cc1 +CC(C)SCc1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 +O=C(c1ccco1)N(c1cc(Cl)ncn1)C1CCN(CCc2ccccc2)CC1 +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CC2CC1CS2 +Fc1cc(Cl)ccc1C(NC1CCN(Cc2ccc(C(F)(F)F)cc2)CC1)c1cccnc1 +CC(C(=O)NCc1ccc(C(=O)O)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 +Cn1c(-c2ccc(-c3ccc(Cl)nn3)cc2)nnc1C1(c2ccc(Cl)cc2)CCC1 +O=C(NNc1cccc(F)c1)C12CC3CC(CC(C3)C1)C2 +CCON=C(c1ccc(F)c(F)c1)c1ccc(CN2CCC3(CC2)OCc2cc(F)ncc23)cn1 +CCOc1cc2cc(-c3c(C)nc(NCc4cc(OC)cc(OC)c4)nc3NC3CC(CO)C(O)C3O)oc2c(C)n1 +O=[N+]([O-])c1cc(NCc2cccc(I)c2)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Nc1c(-c2nc3ccccc3[nH]2)c(O)nc2cnccc12 +CC(C)C(O)Nc1nc(Nc2cccc(-c3cncnc3)c2)c2ncn(C(C)C)c2n1 +CCC(C)C(CN(CC(=O)NC(CCSC)C(=O)OC)Cc1cccc2ccccc12)NCC(N)CS +COC(=O)c1ccc2[nH]c3c(N4CCN(CCc5ccc(F)c(F)c5)CC4)ncnc3c2c1 +Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc(OCC(=O)O)cc2)c1 +CCC(C(C)C)C(O)C(O)C(C)C1CCC2C3CC(=O)C4(O)CC(F)CCC4(C)C3CCC12C +O=C1C(=O)N(CC(CO)NCCCCNc2ccnc3cc(Cl)ccc23)c2ccccc21 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+COc1ccc2c(c1)C(=O)N(CC1(c3cc4cnc(C)cc4o3)NC(=O)NC1=O)C2 +Clc1cc(Nc2ncnc3[nH]nc(OCCN4CCOCC4)c23)ccc1OCc1ccccn1 +CCOC(=O)CNC(=O)C(CC(=O)Nc1ccc(Br)cn1)NC(=O)c1ccc(-c2ccccc2S(N)(=O)=O)cc1 +COC(=O)N(C)C1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +CC(C)(C)c1ccc(CN2CCC3c4ccccc4CCC3C2)cc1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccccc3)o2)C(C)OC(C)=O)c(C)c1Cl +Cc1c(C(=O)NCCC(=O)O)cn2c1C(=O)N(CCC1CCNCC1)CC2 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccc(N4CCOCC4)cc3)cc12 +CC(NC(=O)c1nn(-c2ccc(Cl)cc2)c2c1CCCC2=Cc1ccc(Cl)cn1)c1ccccn1 +Cn1c2c(c3cc(S(=O)(=O)n4ccc5c(F)cccc54)ccc31)C1CCC(C2)N1 +CC1(C)C2CC=C(CN3CCC(NC(=O)Nc4cccc(OC5CCOC5)c4)CC3)C1C2 +Nc1ncc2c(n1)-c1c([nH]c3ccc(Br)cc13)CCC2 +CC1NC(c2cc(C#N)ccn2)=NC1(c1ccc(F)cc1)c1ccc(F)cc1 +CC(C)Cn1c(C(=O)N(C)C)cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(Cl)c21 +COc1nc(-c2ccccc2Cl)cc2nc(-c3c4c(nn3C)CCC43CCCCC3)[nH]c12 +CNC(=O)C1OC(n2cnc3c(Nc4ccc5c(c4)C(C)(C)N([O])C5(C)C)ncnc32)C(O)C1O +Cc1ccc(-c2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)c(C)n1 +CC(C)N(CC(O)COc1ccc(OCc2ccccc2)cc1C(=O)CCc1ccccc1)C(C)C +O=C(NC1CCN(Cc2ccccn2)CC1)C(O)(c1ccccc1)C1CCCC1 +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)N(CC)CC)c3cccc(Cl)c3)CC2)c(F)c1 +Cc1nn2c(O)c3c(nc2c1-c1ccc(F)cc1)CCCC3 +c1ccc(N=c2sc(-c3ccccc3)cn2CCCCCCn2cc(-c3ccccc3)sc2=Nc2ccccc2)cc1 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5ncco5)cc4)nccc3c2Cl)CS1(=O)=O +N#Cc1ccc(N2N=C3c4ccc(C(=O)O)cc4CCC3C2C2CCCC2)cc1 +COc1ccc(S(=O)(=O)N(CC(=O)Nc2cccc(Cl)c2C)c2ccc(C)cc2)cc1OC +CCCCCCOc1c(-c2ccc(O)c(O)c2)oc2cc(OC)c(OC)c(OC)c2c1=O +CCOc1ncccc1-c1noc(C2CCN2C(=O)c2cc(OC)c(F)cc2-n2nccn2)n1 +C=CC1CC(C(=O)O)=CC(OC(C)C)C1NC(C)=O +N=C1c2ccc(OC(F)(F)F)cc2CN1Cc1cccc2ccoc12 +CC(C)(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1 +O=C1c2ccccc2C(=O)N1CCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1 +COCCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccccc2)CC3)n1 +O=C(c1ccc2occc2c1)N1CCC(N2C(=O)OCc3ccccc32)CC1 +Cc1ccc2nc3c(c(Nc4ccc(N(C)C)cc4)c2c1)CCC3 +Cc1nc2ncccc2cc1-c1ccc2cc(CCN3CCCC3C)ccc2n1 +CCn1c(=O)c2c(nc3n2CCCN3c2ccc(F)cc2)n(CC)c1=O +CCOc1ccc(F)c(-c2c[nH]c(-c3cccc(CN4CCCCC4)c3)n2)c1 +Cc1n[nH]cc1-c1cc2nc(CN3CCCCC3)[nH]c(=O)c2s1 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CN(c4ccc(Cl)cn4)C5)cn3)n2)s1 +Cc1ccc(-c2c(CN)c(CC(C)C)nc3ccc(OCCC(=O)O)cc23)cc1 +Cc1ccc(C2=NN(C(N)=S)C(c3ccc(C)cc3)C2)cc1 +CNC(=O)C=C1COc2c1ccc(OS(=O)(=O)c1ccc(OC)cc1)c2C +N#CNC(=NCCCCCCCOc1ccc(Cl)cc1)Nc1ccncc1 +CCCCCCCCCCCCn1nnc(C(NC(=O)c2ccccc2)c2ccccc2)n1 +CC(=CC(=O)O)c1cc2cccc(-c3cc(C(C)C)cc(C(C)C)c3OCC(F)(F)F)c2o1 +[N-]=[N+]=NC1CC(n2cc(-c3cc(CO)on3)c(=O)[nH]c2=O)OC1CO +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NCC(C)(C)N +O=C1COc2ccc(Cl)cc2CNC(=O)C2CCCN2C(=O)C(C2CCCCC2)NC(=O)CCCCN1 +CCCCCOc1cc2ccccc2cc1C(O)CC#CCCCC(=O)OC +O=c1cc(N2CCOCC2)nc(Cc2nc3cc(C(F)(F)F)ccc3[nH]2)[nH]1 +NCCOc1cccc2c1c1cccc3c1n2C(c1ccccc1)CO3 +Cc1ccncc1-c1cc2cnc(NC(=O)C3CC3)cc2cn1 +COc1cc(C)c(C(=O)O)cc1-c1ccc(C#CCO)s1 +CC1CCc2cc(C(=O)N(C)CC(F)(F)F)ccc2N1C(=O)c1ccc(O)cc1O +Cc1cnn(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C(F)(F)F)n2)n1 +CCCc1nc(C)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +N#Cc1ccc2c(C(=O)NCc3ccc(F)cc3)c(O)n(O)c(=O)c2c1 +CNC(=O)CC(C)(NC(=O)c1cc(OC(C)C(F)(F)F)c(C2CC2)cn1)C1CC1 +CCCN(Cc1c(C(F)(F)F)nc2n(-c3c(C)cc(C)cc3Cl)c(Cl)cn12)CC1CC1 +Cc1cc(C)c(Oc2nc(NC3CCN(Cc4ccc(C(N)=O)cc4)CC3)nc3ccsc23)c(C)c1 +O=C(NNc1ccc(F)cc1)C(=O)c1c[nH]c2ccccc12 +CC(=CCCP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)CO +CCN1CC2(CCN(C(=O)c3nn4c(C(F)(F)F)cc(C5CC5)cc4c3Cl)CC2)OC1=O +[C-]#[N+]C1C(C)=NC(C(F)F)=C(C#N)C1c1cc2c(N)nccc2o1 +CNC(=O)Cc1ccccc1CNC(=O)c1nc(N2CCCCS2(=O)=O)c2cccnc2c1O +Nc1cnc(-c2ccc(C3CCC3)c(OCc3ccc(CC(=O)O)cc3)c2F)cn1 +COC(=O)c1ccccc1S(=O)(=O)N1CCCC(Cn2ccnc2)C1 +N#Cc1c2c3ccc(Sc4ccc(Br)cc4)c4cccc(c-2nc1=O)c43 +O=c1c2c([nH]c3ccc(-c4ccc(COc5ccccc5)cc4)cc13)CCSC2 +OCC1CCCCN1CCc1ccc(Nc2nc(-c3cccc(Cl)c3)cs2)cc1 +O=C(NCC(=O)N(CCO)C1CCS(=O)(=O)CC1)c1cc2cc(Cl)ccc2[nH]1 +CCC(NC(=O)c1ccc2c(c1)ncn2Cc1ccc(Cl)cc1)c1ccccc1 +CCOC1CCC(CS)(C(=O)NC(Cc2ccccc2)C(=O)NC)CC1 +COc1cc(C=C(C#N)c2nc3ccccc3[nH]2)ccc1OCC(=O)Nc1ccccc1C(C)C +COc1cc(NC(=O)N(C)c2cc(Nc3ccc(N4CCN(C)CC4)cc3)ncn2)c(Cl)c(OC)c1 +CCc1ccc(-c2ccc(C(=O)N(C)C3CCN(C(=O)N4CCC(N5CCCCC5)C4)C3)cc2)cc1 +COc1ccc2c(c1)c(C(C)N(O)C(N)=O)c(C)n2C(=O)c1ccc(Cl)cc1 +O=C(CC1CCOCC1)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +CN1CCC(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)(S(C)(=O)=O)CC1 +COC(=O)c1c(NCC(OC)OC)n(-c2ccccc2)c(=S)n(-c2ccccc2)c1=O +Nc1ccc2cc(NCCc3ccccc3)cc(Nc3ncccn3)c2n1 +N=C(N)c1ccc(CNC(=O)C2CCCN2C(=O)CCc2ccccc2)cc1 +CCC1CN(C2CC3(C)C(CCC4C5CCC(C(C)=O)C5(C)CC(=O)C43)CC2O)CCO1 +COC(C)(C)c1nnc2cc(-c3cc(C(=O)NC4CC4)cc(F)c3C)ccn12 +CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)cn1C1CC2C1)c1nc[nH]n1 +COc1ccc(-n2c(SCC#N)nc3sc4c(c3c2=O)CCCC4)cc1 +NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CCc1cc(-c2ccccc2)on1 +O=c1c2cccnc2ncn1Cc1nc(CC(F)c2ccc(Cl)cc2)no1 +CC(C)c1cc(Oc2c(F)cc(NC(=O)C(=O)O)cc2F)ccc1O +Cc1ccc2c(-c3nnc(SCCCN4CCc5ccc6nc(C(C)(F)F)oc6c5CC4)n3C)cccc2n1 +CC(C)OCC(Oc1ncnc2c1cnn2-c1ccccc1Cl)C(=O)Nc1ccc(C#N)cn1 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+COc1ccc(-n2nc(C(F)(F)F)cc2C(=O)Cc2ccc(-c3ccccc3CN3CCC(O)C3)cc2)cc1 +O=C(Nc1cc(CN2CCCC2)[nH]n1)Nc1cccc2c1C1CCCN1C2=O +c1ccc2ncc(N3CCC(c4nc(C5CCCCC5)no4)CC3)cc2c1 +Cc1nc2cccnc2n2c(-c3cc(OC4CCOCC4)ccc3Cl)nnc12 +O=C(O)C1CCN(C2CCC3(C2)C(=O)c2cc(F)ccc2Sc2ccccc23)CC1 +Nc1n[nH]c2cccc(-c3ccc4c(C(=O)Nc5cc(Cl)cc(Cl)c5)cccc4c3)c12 +NCC1OC(OC2C(N)CC(N)C(O)C2OC2OC(CO)C(OC3OC(CN)C(O)C(O)C3O)C2O)C(N)C(O)C1O +C[n+]1ccc(Nc2ccc(Cc3ccc(N(CCO)CCO)cc3)cc2)c2ccccc21 +O=c1ccn(CC(CCO)COC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1 +COc1cc2c(NC3CCN(C4CC4)CC3)nc(N3CCS(=O)(=O)CC3)nc2cc1OCCCN1CCCC1 +CN1C(=O)NCc2c(NC(=O)NC3CC(C)(C)Oc4cc(C(F)(F)F)ccc43)cccc21 +CC1(C)CC1C(=O)NC(=CCCCCCSCC(N)C(=O)O)C(=O)O +Cc1cccc(COc2ccc3c(c2)-c2nnc(C)cc2C3=O)c1 +COc1cc(-c2cc(=O)c3c(O)c(OC)c(OC)c(OC)c3o2)ccc1O +CCc1cc(NC(=O)NCCN2CCC(O)(Cc3ccccc3)CC2)c2sccc2n1 +NC1CCN(S(=O)(=O)c2ccc3[nH]c(-c4cc5ccccc5nc4O)cc3c2)C1 +CCCCN(CCCC)C(=S)NN=Cc1c(C)nn(-c2ccccc2)c1O +N#Cc1ccc(C(c2ccc(C#N)cc2)n2ccnc2)cc1 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+Nn1c(S)nnc1-c1sc(NC(=O)CCl)cc1-c1ccccc1 +CC(SC(CCc1ccccc1)C(=O)O)C(=O)N1C(C(=O)O)CC2CCCCC21 +CC(C)(CC(=O)N1CCc2ccccc2C1)NCC(=O)N1CCCC1C#N +O=C(CCCCCCNC(=O)c1cnc(N2CCCNCC2)nc1)NO +CC(C)Nc1c(C(N)=O)nnc2ccc(-c3ccncc3)cc12 +CN1C(=N)NC(C)(c2sc(-c3cccc(-c4ncno4)c3)cc2F)CS1(=O)=O +CC1(C(=O)O)CCC(CC(=O)N2CCc3c(n(Cc4ccc(F)cc4)c4ncccc34)C2)CC1 +CC(C)c1c(Cc2c(F)cccc2Cl)nc(SCC(=O)c2ccccc2)[nH]c1=O +CCCCCN(C(=O)c1ccc(C)cc1)C(C)c1nc2ccccc2c(=O)n1-c1ccccc1CC +O=C(c1cc(CO)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2)N1CCCC1 +CCCCC#Cc1nc(NCc2cccc(Cl)c2)c2ncn(C3SCC(O)C3O)c2n1 +Cc1ccc(-c2ccc(N(CC(N)CC(C)C)C(=O)C3CC3c3ccccc3)cc2)cc1 +C=CC(=O)Nc1cc2c(Nc3ccc(F)c(F)c3F)ncnc2cc1OCC1CCN(C(C)=O)CC1 +O=C1CCC(c2ccc(OCCCN3CCCC3)cc2)=NN1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(c3cccc(C(N)=O)c3)CC2)ncc1[N+](=O)[O-] +CCOC(O)=C1C(COCc2cc(=O)n(C(C)C)c(N)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +CS(=O)(=O)c1ccc(-n2cc(C(F)(F)F)nc2-c2ccccn2)cc1 +COc1cc(OCc2csc(C3(F)CCOCC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CCN1CCC(N=CC(C=N)c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)C1 +COc1cc(C)nc(OC)c1NC(=O)N(Cc1ccc(Oc2ccc(F)cc2)cc1)C1CCCCCC1 +COC(=O)C1C(=O)C2=C(CC1C)NC(=O)CC2c1ccc(Cl)cc1Cl +CC(C)n1ncc2cc(NC(=O)c3ccc4cc5n(c4n3)C(C)CCNC5=O)cnc21 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NC4CCCC4)nc23)N1 +COc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)ccc1O +CCCCCCCc1ccc(NC(=O)Nc2c(C(C)C)cccc2C(C)C)cc1 +CN(C)S(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CCC(=O)O)C(=O)CCC3)C(=O)N2 +Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1CCN(CC(F)F)CC1 +Cc1nn(-c2ccc(Cl)cc2)c(O)c1C(c1cccc(O)c1)c1c(C)[nH]n(-c2ccc(Cl)cc2)c1=O +Cc1ccc2c(=O)c(C(=O)NC3CCCCC3)cn(Cc3ccc(F)cc3)c2n1 +C=C(COC)C1CCC2(COC(=O)n3ccnc3)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCCN(CC3CC3)C2=O)CC1 +COC(=O)N1CCC(N(C)C(=O)CN(CC(=O)NCCN2CCCC2)c2cc(Cl)ccc2Oc2ccc(Cl)cc2)CC1 +Cc1ccc(C)c2c1NC(=O)C2=NNC(=O)CCc1ccc(O)cc1 +CN(c1ccc(Oc2ccccc2)cc1)S(=O)(=O)c1ccc(Cl)cc1 +CCOc1ccccc1C(=O)N1CCN(c2cccc(Cl)c2)CC1 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+Nc1ncnc2c1c(-c1ccccc1)cn2-c1ccc(CO)cc1 +Cc1cccc(C2(O)CCN(C(c3ccccc3)c3ccccc3)CC2)c1 +CCCn1cc(-c2cn3ncc(C(N)=O)c(NC4CN(C(=O)C5(C#N)CC5)CC4CC)c3n2)cn1 +COC(=O)c1ccc(-c2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc2)cc1 +Nc1ncc(-c2nc(N3CCOCC3)nc3c2CCN3C2CN(S(=O)(=O)C3CC3)C2)cn1 +CCC(O)(C#Cc1cn2nc(-c3ccco3)nc2c(N)n1)CC +CC(C)CN(Cc1ccc(N2CCN(C(=O)C3COC3)CC2)cc1)S(=O)(=O)Cc1ccccc1 +OC1CCN(Cc2ccc(I)cc2)CC1N1CCC(c2ccccc2)CC1 +O=C1CCc2ccc(NC(=O)NC3CCc4cc(Cl)ccc43)cc2N1 +CCCCCCCCC[n+]1ccc2c(c1)C1C(CC2)CCN1C +O=C1NC(C(=O)O)Cc2ccc(cc2)OCC=CCOc2cccc(Cl)c21 +Cc1c(F)c(Oc2cccc(OC(C)C)c2)nc(Oc2cccc(C(=N)N)c2)c1F +CCOc1ccc(CCNC(=O)C(CC(=O)O)NC(=O)CCCOc2ccc(C(=N)N)cc2)cc1 +COc1cc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)ccc1C +COCCN(C)c1ccc(-n2c(O)nnc2-c2cc(C(C)C)c(O)cc2O)c[n+]1[O-] +Cc1c(N2CC3CCC(C2)O3)nc2n(c1=O)CCC(C(F)(F)F)N2CCCc1ccccc1 +CCOC(=O)C1CCCN1C(=O)c1cc(C(=O)NC(CC)c2ccccc2)c2n1CCOC2 +NCc1ccc(C(=O)NC(c2ccc(Cl)cc2)c2nc3ccc(-c4cn[nH]c4)cc3c(=O)[nH]2)cc1 +CNc1nc2[nH]c(-c3cccc(N(C)CCOC)n3)cc2c2c1ncn2C +Clc1nc2c(NCc3ccccc3)nc(N3CCNCC3)nc2nc1N1CCCC1 +CCOC(=O)Nc1cc2c(c(N)n1)N=C(c1cccc(NC(=O)c3ccc(N=[N+]=[N-])cc3)c1)C(C)N2 +N=C(N)c1ccc(C=C2CCC(=Cc3ccc(C(=N)N)cc3)C2=O)cc1 +CCC(C)(C)NC1C(=O)C(=O)C1CNc1c(C)cc(Cl)cc1Cl +COC(=O)CC1CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(CC2CC2)C1=O +COC1CCN(c2ncc(Cl)c(N3CCC(Oc4ccc(C(C)NC(C)=O)cc4)C3)n2)CC1 +CN1C(=O)C2(CC(C)(C)Sc3ccc(-c4cncc(Cl)c4)cc32)N=C1N +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2N)cc1 +CCC(CO)Nc1nc(NCc2ccncc2)c2ncn(C(C)C)c2n1 +CC1(O)CCCN(S(=O)(=O)c2ccc(C(C)(C)C)cc2)CC1 +CC(=O)OCC1C2CC3CCC1N3CC2=Cc1ccc2ccccc2c1 +N#Cc1nc(-c2ccnc(Nc3ccc(CN4CCOCC4)nc3)n2)ccc1N1CCC(O)C1 +Cc1cccc2cc(-c3cn4nc(C(C)(F)F)sc4n3)oc12 +CN1CCN(CC(=O)Nc2cccc3c2C(=O)c2c-3n[nH]c2-c2ccc(N(C)C)cc2)CC1 +CC(C)N1CCN(CCN2CCN(c3ccc(F)c(C#N)c3)C2=O)CC1 +CCC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cnn(C)c4cc3F)n2n1 +Cc1ccccc1-n1nc(-c2c(-c3ccc(F)cc3Cl)nc3ccccn23)ccc1=O +CC(C)(C)OC(=O)N1CCC(OC2CCC(Oc3ccc(S(C)(=O)=O)nn3)CC2)CC1 +CCOC(=O)c1ccc(NC2CCCC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +O=S(=O)(Cc1ccc2c(c1)CCNCC2)c1ccc(-c2ccc(F)cc2)nc1 +Cc1cccc(C)c1-c1nc(C(=O)Nc2cccc(C(=O)O)c2)c(CCC23CC4CC(CC(C4)C2)C3)[nH]1 +NC(Cc1ccccc1)C(=O)NCCOCCOCCNC(=O)c1ccc(S(N)(=O)=O)cc1 +O=S(=O)(c1ccc(Cl)c(Cl)c1Cl)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 +Cc1ccc(CNCCC2(c3ccccn3)CCOC3(CCCC3)C2)o1 +CC(=O)N1CCC(C)(c2ccccc2)c2cc(NC(=O)NCc3cccc(Cl)c3)ccc21 +CCCn1c(=O)c2cn[nH]c2c2ccc(-c3ccncc3)cc21 +O=C1COc2ccc(-c3n[nH]c(C4CCCCN4C(=O)COc4ccccc4)n3)cc2N1 +COc1cccc(NC(=O)C(O)C(N)CC2CCCCC2)c1 +O=C(c1ccccn1)C1CCCN1C(=O)C1CCCN1C(=O)CCCc1ccccc1 +O=C1NC(=S)N(Cc2ccco2)C(=O)C1=Cc1ccc(-c2ccc([N+](=O)[O-])cc2)o1 +Cc1cc(=O)oc2cc(OCc3nnc(SCCN4CCOCC4)n3-c3ccc(Cl)cc3)ccc12 +O=C(Cn1c(-c2ccccn2)nc2ccccc21)c1ccc(Cl)cc1 +Cn1c(=O)c2c(-c3cccc(Cl)c3)n3c(c2n(C)c1=O)C(c1ccc(Cl)o1)NCC3 +Cc1ccc(CCN2CCN(c3cccc4cc(C(=O)N(C)C)oc34)CC2)nc1 +C=C1C(=O)OC2C1CC1(O)C3Cc4ccc(O)c5c4C1(CCN3CC1CC1)C2O5 +CCN(CC)c1ccc(CN(C23CC4CC(CC(C4)C2)C3)S(=O)(=O)c2ccc(C)cc2)cc1 +O=C(O)c1cccc(-c2cnccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 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+COc1ccc(CN2CC3CCN(S(=O)(=O)c4ccc(Cl)cc4Cl)CC3Oc3c(NC(=O)C4CC4)cccc3C2=O)cc1 +Cn1cc(-c2cc(OCCCCC(=O)O)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +O=C(O)CCc1cc(Br)c(OCc2cccc(Cl)c2)c(Br)c1 +CCn1c(Cn2ccc(C(F)(F)F)c(Oc3cc(Cl)cc(C#N)c3)c2=O)n[nH]c1=O +CC1OC(n2cnc3c(N)nc(OC4CCCC4)nc32)C(O)C1Oc1ccccc1 +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCc4ccc(OC)cc4)c3)cc2N=C(N)C1 +CCOc1cc(OC2CCNC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 +CCCSc1nc(N2CCC(CC(=O)O)CC2)ccc1C(=O)NC1CCCCC1 +Cc1c(Cl)ccc2[nH]c(-c3ncsc3N3CCN(C(=O)Cn4cnc5cccnc54)C(C)C3)nc12 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5cc(C(F)(F)F)n[nH]5)cc4)nccc3c2Cl)CS1(=O)=O +COc1cccc(N2C(CN3CCOCC3)=Cc3cc(S(N)(=O)=O)sc3S2(=O)=O)c1 +CN(C)Cc1cccc(-c2cc3c(-c4cnn(C)c4)ccnc3[nH]2)c1 +O=C(NCCO)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cccc(Cl)c3Cl)c(F)c2)CC1 +COc1c2occc2c(OC)c2c(=O)c(-c3cc(-c4ccc(F)cc4)[nH]c(=S)n3)c(C)oc12 +CC(C)(O)c1cncc(-c2nc3ccc(F)cc3n2C2CC2)c1 +Cc1cccc2c(C(=O)C3CSC(c4cccnc4)N3)c[nH]c12 +O=c1[nH]c(C2CCN(S(=O)(=O)C3CC3)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +Cn1cnc(S(=O)(=O)NCCOc2cc(C(CN)Cc3ccccc3)ccc2F)c1 +COc1cccc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1OC +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=NC#N)c(F)c2)cn1C(C)C +Cc1oc(-c2c(Cl)cccc2Cl)nc1CN1CCC(C(=O)NCCCN2CC(C)CC(C)C2)CC1 +C#CCOc1ccc2c(c1)n1ncc(I)c1n[n+]2[O-] +CC1CCc2cc(-c3ncnc4cccc(F)c34)ccc2N1C(=O)c1ccc(O)cc1O +CC1CC2CSC(N)=NC2(c2nc(NC(=O)C3CC3)cs2)CO1 +Cc1[nH]c2ccccc2c1CCCN1CCC(c2noc3cc(F)ccc23)CC1 +Cc1ccc2c(c1)nc(CCc1ncc3cccnn13)n2-c1ccccc1 +CC(C)C(C(=O)NC1CCCCC1C(=O)O)N(C)S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(N3CC(CO)C3)c2c1=O +CC1(n2cc(C(=O)c3cncc(NC(=O)Cc4ccc(Cl)cc4)c3)c3cncnc32)COC1 +O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2cc([N+](=O)[O-])ccc2F)CC1 +CC(N)(CCc1ccc2c(c1)CCc1c-2noc1-c1noc(-c2ccccc2)c1C(F)(F)F)C(=O)O +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(=O)N1CCN(C)CC1 +Cc1ncccc1NC(=O)c1ccc2c(c1)CCC1CC(OP(=O)(O)O)(C(F)(F)F)CCC21Cc1ccccc1 +CCCS(=O)(=O)NCCOc1ccc2c(c1)C(Cc1ccccc1)C(N1CCC1)CC2 +Clc1cccc(-c2cccc(-n3nnc(-c4ccccn4)n3)c2)c1 +O=C(c1ccc2occc2c1)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 +Cc1cc(Cl)ccc1C1c2c(nn(C3CCN(C)CC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F +O=C(Nc1ccc(C2=CCN(C(=O)c3cccnn3)CC2)cc1)N1Cc2ccccc2C1 +CNC(=O)c1ccc(NC(=O)Nc2ccc(-c3nc(N4CCOCC4)c4cccnc4n3)cc2)cc1 +Oc1c2cnc3c(c2nn1-c1ccc(OC(F)(F)F)cc1)CCCC3 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(OC(C)C)c2)[nH]1 +CCCCc1cc(OC2CCN(CCS(=O)(=O)CC)CC2)c2ncccc2c1 +Cc1[nH]c(C)c(-c2ccc(Oc3cccc(Cl)c3)cc2)c(=O)c1Br +Cc1cc(N2CCC(N3CCCC3)CC2)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +CC(NC(=O)OCc1ccccc1)C(=O)NC(C)C(=O)NN(CC(N)=O)C(=O)C=CC(=O)NCc1ccc(F)cc1 +C=C1CC(C=CC(C)=CCC2OC(C)C(NC(=O)C=CC(C)OC(C)=O)CC2C)OC(CC(=O)O)C1 +CC(Oc1cc(C(N)=O)nc(-c2ccc(Oc3ccc(C#N)cc3)cc2)n1)C(N)=O +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCN(C(C)(C)C(N)=O)C1 +CC1CCN(c2ncc3cc(F)ccc3n2)CCN1C(=O)c1ccccc1-n1nccn1 +CC(=O)Nc1ccc2[nH]cc(CC(NC(=O)c3ccc4c(c3)nc(-c3ccoc3)n4C3CCCCC3)C(=O)O)c2c1 +CN1CCN(Cc2cn(S(=O)(=O)c3cccc(F)c3)c3ccccc23)CC1 +CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(C)c1 +Cc1cc(C2CNCCO2)ccc1NC(=O)c1ccc(Cl)nc1 +COc1ccc(C(=O)n2nc(-c3ccco3)nc2N)cc1 +Cn1nc(-c2cnc(N)c(-c3nnc(C(C)(C)C)o3)n2)nc1C1(c2ccccc2)CC1 +Cc1ccccc1NC(=O)N(CCCN1C2CCC1CC(n1c(C)nnc1C(C)C)C2)c1ccccc1 +CCC(C1CC1)n1cc(Cl)nc(Nc2cc(C)c(OC)cc2C)c1=O +CC(C)(O)c1cccn2c(-c3ccnc(NC4CCC(NS(C)(=O)=O)CC4)n3)cnc12 +CC(=O)c1ccc(OCc2ccc(Oc3cccc(-c4nn[nH]n4)c3)cc2)c(C)c1O +CC1CC1C(=O)Nc1snc(-c2ccc3nn(C)cc3c2)c1-c1cccc(C2CC2)n1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)c(F)c2)cn1C(C)C +CCCN(CCC)Cc1c(C(=O)NN=CC(C)=Cc2ccccc2)nnn1-c1nonc1N +CCCCOc1ccc(C(=O)NN2Cc3ccccc3NC2c2ccc(OC)cc2)cc1 +CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCCCC4)ccc31)CN(C1CCCC1)C2 +O=C(CCn1nnnc1-c1ccc2c(c1)OCO2)c1ccccc1 +COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)n(CCO)c3ccc(Cl)cc23)CC1 +CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCC(F)C4)n3)cc2)C1=O +CC(Nc1nc(Nc2cn(C)cn2)c2[nH]ccc2n1)c1ncc(F)cn1 +CC1(CC(=O)NCc2ccc(-c3ccc(F)cc3)cc2)CC2(CCCCC2)OO1 +CC(NP(=O)(OCC1OC(C#N)(c2ccc3c(N)ncnn23)C(O)C1O)Oc1ccccc1)C(=O)OC1CCC1 +CCOc1ccc(N(CC(=O)O)C(=O)C(C)CS)cc1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2Cl)nc1-c1cc(C(F)(F)F)ccc1F +CNCc1cc(-c2cccnc2F)n(S(=O)(=O)c2ccccn2)c1 +O=C(Nc1ccccc1C(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccno1)OCc1ccccn1 +Cc1ccc(OCC(=O)Nc2cc(-c3nccs3)nc(-c3ccc(C)o3)n2)cc1 +Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(C(=O)c3c(F)cccc3F)CC2)c(=O)n(-c2ccc(Cl)cc2)n1C +COc1cc(F)ccc1-c1nc(Nc2cc(F)cc(CS(=O)(=NC#N)C3CC3)c2)ncc1F +c1ccc2c3c([nH]c2c1)CC1CCC3N1CCCCc1nccs1 +N=C(N)c1ccc(CNC(=O)C2CCCN2C(=O)C(CO)NS(=O)(=O)Cc2ccccc2)cc1 +CC(C)CCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCc3nnnn3C3CC3)ccc1-2 +Nc1ncc(-c2nc(N3CCOCC3)nc3c2CCN3c2ccc(CN3CCOCC3)cc2)cn1 +O=C(Nc1ccc(C2CCNC2)cc1)Nc1cccc2cccnc12 +CC(=O)Nc1cccc(C2CCN(CCCNc3nc4ccccc4n3-c3cccc(Cl)c3)CC2)c1 +CCCCCCC(Oc1ccc(C(=O)NCCC(=O)O)cc1)C(=O)Nc1ccc(-c2ccc(Cl)cc2Cl)cc1 +N=C(c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2cc3ccccc3cc2F)c(F)c1)N1CCCC1 +Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCC(F)(F)CC1 +CC1(c2ccccc2)CCN(c2cccc(-c3ccc(F)cc3F)c2)C(=O)O1 +COC(=O)c1coc(CN2CCC(CNC(=O)c3n[nH]c4ccc(OC)cc34)CC2)n1 +NC(=O)CCNC(=O)c1ccccc1SC(=O)NC1CCCCC1 +O=C(Nc1cccc(F)c1)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)c2ccccc12 +COc1cc2cc(C(=O)N3CC4CC45C3=CC(=O)c3[nH]c(C)c(CN(C)C)c35)[nH]c2c(OC)c1OC +CCNc1cc(-c2c[nH]c(CN=C(NC)NC#N)n2)ccn1 +CC1(C)Cc2nc(N3CCOc4ccc(-c5ccn[nH]5)cc43)sc2C(=O)N1 +CC(C)(C)c1nc(N2CCN(CCCCNC(=O)C3CCC(c4ccccc4)CC3)CC2)cc(C(F)(F)F)n1 +CS(=O)(=O)c1cccc(-c2cccc(-c3cc(C(F)(F)F)nn3-c3ccccc3Cl)c2)c1 +Nc1nc(C(=O)NCc2cccc3cccnc23)c2ccc(F)cc2n1 +Cc1ccc(S(=O)(=O)Nc2cncc(-c3cnc(N)nc3)c2)cc1 +COCC(NC(=O)Nc1cc2[nH]nc(OCc3ccccc3)c2cn1)c1ccccc1 +COc1cccc(NC(=O)N2CCCC(CCN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 +CC(C)(C)N(NC(=O)c1ccc(F)cc1)C(=O)c1ccccc1Cl +CC(C)(C)c1ccc(S(=O)(=O)c2ccccc2Cl)cc1 +CC(C)CN(Cc1cc(Br)c2c(c1)OCCCO2)C(=O)C(C)CNCc1ccccc1 +COc1cccc(CSc2nc(Cc3ccccc3)c(C)c(=O)[nH]2)c1 +Cc1cc(Nc2nc(N3CCN(C(=O)c4ccccc4C)CC3)nn3cccc23)n[nH]1 +COc1cc(-c2cc(C)cs2)ccc1S(=O)(=O)Nc1cccc(N2CC(C)NC(C)C2)c1 +Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(F)cc1 +O=C(CCCCCc1ccccc1)c1nc2ccc([N+](=O)[O-])cc2o1 +CC1CN2c3c(cc4c(N5C(=O)OCC5C(O)CO)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CCOC(=O)C(C)NP(=O)(OCC1OC(c2cnc3c(N)ncnn23)C(C)(F)C1O)Oc1ccccc1 +O=C(COc1ccc2cc(C(=O)Nc3ccccc3)ccc2c1)NCc1ccc(OP(=O)(O)O)c(OP(=O)(O)O)c1 +CC(=O)N1CCN(C(=O)C=Cc2ccc(Sc3ccc(Cl)cc3Cl)c([N+](=O)[O-])c2)CC1 +OCCC1CCCCN1CCCCn1cnc2c(O)nc(Nc3ccccc3)nc21 +Cc1c[nH]c2ncnc(N3CCN(C(=O)Nc4cccc(C(=O)NCCO)c4)C(C)C3)c12 +CCOc1ccc(N2CC(CN3CCC(O)(c4ccc5c(c4)OCO5)CC3)OC2=O)cc1 +Cc1cccc(-c2c(O)nc3cc(Cl)c([N+](=O)[O-])cc3c2OCCC2CCCCN2)c1 +COc1cc(CNCc2ccncc2)ccc1OCc1cnc(Cl)c(Cl)c1 +c1ccc2c(c1)ccc[n+]2CCCCCC[n+]1cccc2ccccc21 +COc1ccc(COc2ccc(-c3ccn4c(CC5CC5)nnc4c3C(F)(F)F)cc2)cn1 +C=C(CO)COC1(c2ccc(Cl)cc2)c2ccccc2C(=O)N1Cc1ccc([N+](=O)[O-])cc1 +NC(=O)CCNc1ncc2c(n1)c(Nc1cccc(Cl)c1)nc1cc(C(=O)O)ccc12 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+COc1ccc(-c2nnc(N3CCN(c4ncc(C(C)(C)O)c(C(F)(F)F)n4)CC3)c(C)c2C)cc1 +NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)cc1 +CCNC(=O)Nc1ncc2cc(-c3cc(F)ccc3C)ccc2c1Cl +O=C(NC(c1ccc(Cl)cc1)c1cccnc1)c1ccc(Cl)cc1 +O=C(O)c1ccc(CCCN2C(=O)CCC2CCC(O)Cc2ccc(F)cc2)s1 +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(CCc3ccoc3)CC2)cc1 +O=C(O)c1cc(-c2cccc(C(F)(F)F)c2)ncn1 +Cc1cn(-c2ccc3n(c2=O)CCN(C(C)C2CCC(c4ccc(Cl)cc4OC(F)(F)F)O2)C3=O)cn1 +COc1ccc(COc2ccc(-c3cc(C(=O)O)c4cnn(Cc5ccncc5)c4n3)cc2)cc1 +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2[nH]ncc2c1 +COc1ccc(-c2cc(-c3cc(OC)c(OC)c(OC)c3)[nH]n2)cc1 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)Nc2cccc(F)c2C)cc1 +O=c1nc(N2CCOCC2)cc(N(CCCO)Cc2cccc3ccccc23)[nH]1 +CCSc1ccc2ncc(-c3ccnc(Nc4ccc(S(=O)(=O)NCCOC)cc4)n3)n2c1 +O=C1CN(c2ccc(Cl)c(Cl)c2)C(=O)N1S(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(Cn4cccn4)c4ccccc43)CC2)C(C)C)c1 +CC(C)(C)OC(=O)N1CCN(C(=S)SCc2cn(Cc3cc(=O)oc4c(O)c(O)ccc34)nn2)CC1 +O=C(OC12CC3CC(CC(C3)C1)C2)c1cc(N(O)C2CCCO2)on1 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+CC(C)N(CC#CCCC(=O)C(O)(c1ccccc1)C1CCCCC1)C(C)C +NC1CCCN(c2ncncc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)C1 +NS(=O)(=O)c1ccc(Nc2ncnc(Cl)c2[N+](=O)[O-])cc1 +CN(CCCc1ccc2c(c1)C(Cc1cccc(F)c1)C(N)CC2)S(=O)(=O)CC1CC1 +CN1C(=O)N(C)C2(NC(=O)NC2=O)c2ccccc21 +Nc1c2c(nc3c1C(c1ccccc1Br)c1ccc4cccnc4c1O3)CCCC2 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4CCC(F)(F)C4C3)n2)cn1 +COCC(C)(C)OC(=O)N1CCC2(CC1)CC2CNC(=O)N1Cc2ccncc2C1 +Cc1ccc(CN2CCC(C(=O)Nc3ccc(-c4cc5ccccc5[nH]4)cc3)CC2)o1 +Cc1ccc(C(N)=O)cc1Nc1cc(=O)n(C)c2c1cnn2-c1cc(F)ccc1F +CC(C)CC(NC(c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(F)(F)F)C(=O)NC(C#N)c1ccccc1 +CC12CCC(=O)C=C1NCC1C2CCC2(C)C(C(=O)NCc3ccccc3)CCC12 +O=C(O)CN1C(=O)C(NC(=O)c2cc3sc(Cl)c(Cl)c3[nH]2)Cc2ccccc21 +N#CCC(=O)Nc1ccc(Cl)c(-c2nc3cc(C(F)(F)F)ccc3s2)c1 +Nc1nc(N)c2nc(CNc3ccc(C(=O)NC(CCCCP(=O)(O)O)C(=O)O)cc3)cnc2n1 +N#CCNC(=O)C(Cc1cccc(-c2cccnn2)c1)NC(=O)c1ccccc1 +COc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 +Cc1cc(Nc2nccc(-c3nccs3)n2)cc(C(F)(F)F)c1 +N#Cc1ccc2cc(CN3CCN(c4ccccc4Cl)CC3)[nH]c2c1 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+C[N+](C)(Cc1ccc(NC(=O)C=Cc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1)C1CCOCC1 +O=S(=O)(NCc1ccco1)c1ccc(Nc2ccc(F)cc2F)cc1C(F)(F)F +CN(C)C1CC=C(c2c[nH]c3ccc(Br)cc23)CC1 +Cc1cc(C)c(S(=O)(=O)NC(C)CNc2cccc3c2cnn3-c2ccc(F)c(C)c2)c(C)c1 +CCCCOc1cc(Cc2cnc(N)nc2N)ccc1OCc1cc(OC)c(OC)c(OC)c1 +Clc1cccc(-c2nccnc2Oc2ccc(Nc3ccccn3)cc2)c1 +C=C(C)COC1CN(C(=O)C=Cc2cnc3c(c2)CCC(=O)N3)C1 +CSC(=S)N1CC2(CCCCC2)COC1=Nc1ccc(F)c2ccccc12 +C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2)c(F)c1 +CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3Cc2ccoc2)c2c(C)cccc2C)cc1 +Cc1c(OCCN2CCN(C)CC2)cn2ncnc(Oc3ccc(NC(=O)c4cc(Cl)ccc4F)cc3F)c12 +COc1ccc(N2CCN(c3nc(Nc4cc(C(C)(C)C)ccc4C)cc(C(=O)NCC4CCCO4)n3)CC2(C)C)cc1 +Oc1nc2cc3cc(OCCCc4nnnn4C4CCN(CC5CCCCCC5)CC4)ccc3[nH]c-2n1 +Cn1cnc(S(=O)(=O)N(Cc2ccc(F)c(F)c2)c2cc3ccccc3s2)c1 +COc1ccc(-c2csc(Nc3ccc(CCN4CCC(O)CC4CO)cc3)n2)cc1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(C(N)=O)c1ccc(F)cc1 +CC1=NC(=S)N(C(=O)OC2CCN(Cc3ccc(F)cc3)CC2)C(c2ccccc2C(F)(F)F)C1=C(O)OC(C)C +c1cncc(CNc2ncccc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c1 +O=C(c1ccc(Br)c2ccccc12)c1cn(CCN2CCOCC2)c2ccccc12 +O=C(NC1CCC(Nc2cc(-c3cccc(NCC4CCCNC4)n3)c(Cl)cn2)CC1)OCc1ccccc1 +Cc1cccc(CNC(=O)c2cc(-c3ccco3)nc(N)n2)c1 +O=C(Nc1ccc(-c2ccc3ccccc3c2)cc1)Nc1ccc2c(c1)NC(=O)C2=Cc1ccc[nH]1 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)N(c3ccccc3)c3ccccc3)CCC12 +COc1cccc2occ(Cc3coc4ccccc4c3=O)c(=O)c12 +CC(C)c1cc(-c2ccccc2)cc(-c2ccccc2)[n+]1Cc1ccc(S(N)(=O)=O)cc1 +Ic1ccc(CNc2ccc3c(c2)C24CCCCC2C(C3)N(CC2CC2)CC4)cc1 +Cc1cn2c(N3CCN(C(=O)CCS(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)cccc2n1 +CCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2C)OCO3)cc1 +NCCC1CCN(C(=O)C(O)(c2ccccc2)C2CCCC2)CC1 +CCCCC1CN(C2CCOCC2)C(=O)N1C1CCN(C2(C)CCN(C(=O)c3c(C)ncnc3C)CC2)CC1 +NC(C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl)c1ccccc1 +CC(NC(CCc1ccccc1)C(=O)O)C(=O)N1CC(OC(=O)NC(CS)Cc2ccccc2)CC1C(=O)O +Cc1cccc2[nH]c(C(=O)c3cc4cc(OCCN5CCCCC5)ccc4[nH]3)cc12 +OCC1OC(n2cnc3c(Nc4ccccc4F)ncnc32)C(O)C1O +CN(C(=O)c1nn(C)cc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1)C1CCCCC1 +CN(C)c1cccc2c(S(=O)(=O)Oc3cccc4c3C(=O)C=C(N3CC3)C4=O)cccc12 +CC(COc1cc2oc3c(c2cc1Cl)C(=O)c1cccnc1C3=O)N(C)C +COc1cc(C2C=C(c3ccccc3)Nc3ncnn32)cc(OC)c1OC +CC(Nc1ncnc2[nH]c(-c3ccc(CN4CCC(NCCCCCCCC(=O)NO)CC4)cc3)cc12)c1ccccc1 +NS(=O)(=O)c1ccc(N=Cc2ccc(C=Nc3ccc(S(N)(=O)=O)cc3)cc2)cc1 +CC(C)c1cc2oc(N3CCC(C(=O)NC4CCCC(CO)C4)CC3)nc2cc1Cl +N#CCN1CN(C2CCCCC2)c2c(cnc3[nH]ccc23)C1=O +Cn1nc(-c2cccc(N3CCCC(N)C3)n2)c2cc(-c3cccnc3)ncc21 +COC(=O)CNCC(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3CCCS3)c(=O)c2=O)c1O +O=C(OCN1C(=O)C2=C(C3CCC2C3)S1(=O)=O)c1c(Cl)cccc1Cl +COc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCN(S(=O)(=O)c4ccc(C)cc4)CC3)s2)cc1 +CNC(=O)c1cccc(NC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)c1 +CC(C)(Cc1csc2ccccc12)NCC(O)COc1ccccc1C#N +CN1CCC(c2ccc(Nc3nc4c(NCc5ccccc5N(C)S(C)(=O)=O)cccn4n3)cc2)CC1 +Cc1ccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2)cc1C +Nc1nc(NN=Cc2ccccc2F)nc2c1ncn2C1OC(CO)C(O)C1O +CN1C(=CC=Cc2sc3ccc(Cl)cc3[n+]2C)Sc2ccc(Cl)cc21 +O=c1[nH]n(CCCCN2CCN(c3nsc4ccccc34)CC2)c(=O)c2ccccc12 +CCC1=C(C(=O)OCC2CCCCC2)C(c2ccc(O)c(Cl)c2)NC(=O)N1 +CC=CC1(O)CC2CCc3cc(O)ccc3C2(CC)CC1(C)O +NC(=O)c1cnn2cc(-c3ccc(F)cc3)cc2c1NC12CC3CC(O)(CC(O)(C3)C1)C2 +COc1cccc(CNC(=O)c2cc(-c3nnn(CC4CCCCC4)n3)cc(C)n2)c1 +COc1cccc(C2=CCC(N3CCN(c4cccc5ccccc45)CC3)CC2)c1 +Fc1cccc(CCCNC2C3C4CC5C6C4CC3C6C52)c1 +Cc1cc(-c2cnn3c(NCCN4CCOCC4)nc(Oc4cccc(F)c4F)nc23)ccc1C(=O)NC1CC1 +O=C(C=Cc1ccc(F)cc1)NCCCCNc1ccnc2cc(Cl)ccc12 +CCNC(=O)c1noc(-c2cc(-c3ccccc3C)c(O)cc2O)c1-c1ccc(CN2CCCCC2)cc1 +N#Cc1c(N)nc(-c2ccccc2)nc1-c1ccc2c(c1)OCO2 +CC(CO)NC(=O)CCCC=CCC=CCC=CCC=CCCCCc1cccc(C(F)(F)F)c1 +COc1cccc(Cn2c(C(=O)NC3CCN(C(C)C)CC3)c(C#N)c3cccc(C)c32)c1 +COc1cc2c(c3c1C(=O)C(=Cc1ccc(O)c(O)c1)O3)CC(C(C)(C)O)O2 +CC(C)(C)n1ncc(OCc2ccc(CCCCF)cc2)c(Cl)c1=O +COc1cccc(-c2cnc3c(N)nc4ccccc4n23)c1 +CCN1CC2CN(C(=O)CC(N)Cc3cc(F)c(F)cc3F)CCN2C1=O +C=CCN1CC2C(c3ccccc3)=CCC1CN2Cc1ccc(C(=O)N(CC)CC)cc1 +CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1ccc(Cl)cc1 +COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)cc(Cl)c1O +CC(C)CC1C(=O)NC(C(=O)NCC(=O)N(C)C)CCCCN(C)C(=O)OCCCC1C(=O)NO +CC(C)(N)C(=O)N1CCn2c(nc(-c3ccc(F)cc3)c2Nc2ccc(F)c(F)c2)C1(C)C +Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3ccn(C)c3c2)n1 +CC(C)c1sc(C(C)C)c(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +CC(N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCC3 +CCn1nc(C)cc1C(=O)Nc1cccc(Oc2ccc3c(C=Cc4c[nH]cn4)n[nH]c3c2)c1 +CC(C)C(NC(=O)c1cccc(C(=O)O)c1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1 +CCC(=O)NCCCc1cc(OC)ccc1OCc1cccc(OC)c1 +COc1ccccc1C(C)C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(C)c3ccccc3OC)s2)s1 +Nc1c(-c2ccc(F)cc2)c(-c2ccncc2)nn1-c1ccccc1 +COC1CN(c2ncnn3c(C)nc(-c4cnn(C)c4-c4ccc(Cl)cc4)c23)C1 +O=C(OCC#CCSc1nnc(-c2cccc3ccccc23)o1)c1ccc(C(F)(F)F)cc1 +COC(=O)c1c(CNC(=O)C2CCN(S(C)(=O)=O)CC2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +Nc1cc(C(=O)N2CCCC2)cc2nc(-c3ccc(Br)o3)nn12 +COc1cc2c(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)ncnc2cc1OCCCn1nccn1 +CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)c4nnn(-c5nonc5N)c4-c4ccccc4)c3)sc2C1 +CC1(c2nnc3ccc(-c4ocnc4-c4ccc(F)cc4)cn23)CCC1 +NS(=O)(=O)CCNC(=O)C(c1nc2cc(F)c(-c3ccccc3)cc2s1)S(=O)(=O)CCN1CCOCC1 +Cc1c(F)c(Oc2cccc(C(=N)N)c2)nc(Oc2ccc(Cl)c(N(C)C)c2)c1F +c1ncc(CN2CCCNCCNCCCNCC2)cc1CN1CCCNCCNCCCNCC1 +Cc1nc(NC(C)c2cccc(-c3cnc(N4CCOCC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +O=C(NCc1ccc(Cl)cc1Cl)C1CCN(S(=O)(=O)c2ccccc2Br)CC1 +O=S(=O)(Nc1c(O)nc2ccc(C(F)(F)F)cc2c1Cc1cc(Cl)ccc1O)C(F)(F)F +COc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNCC21 +O=C(NCC1CCC2(CCNCC2)CO1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CCCc1cc(=O)n(C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1c(-c2ccn[nH]2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1C +N#CC1(c2ccccc2)CCN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)CC1 +CCn1c(=Cc2cccc[n+]2CCO)sc(=C2Sc3ccccc3N2C)c1=O +COc1cc2c(CN(C)C)c(C)c(=O)oc2c(C=O)c1O +COc1cccc(Nc2nc3cccc(-c4cccc(S(C)(=O)=O)c4)n3n2)c1 +O=C(O)c1ccccc1NS(=O)(=O)c1cccc(-c2cnn(Cc3ccccc3)c2)c1 +CN(Cc1nc2ccccc2[nH]1)C(=O)c1ccc2c(c1)CN(Cc1ccccc1)C(=O)C(CC(=O)O)N2 +O=P(O)(O)C(CCCc1ccc(-c2ccccc2)cc1)P(=O)(O)CO +CN(C)C(=O)n1nnc(Cc2ccc(-c3ccccc3)cc2)n1 +O=C(CCCCc1ccc(O)cc1)NN=Cc1ccc(O)c(O)c1O +Nc1ncc(-c2ccc(-c3ccccc3Sc3cnccn3)cc2F)cn1 +N#Cc1ncc2nc1OCC=CCOc1cc(OC(=O)N3CCC(N4CCCCC4)CC3)c(Cl)cc1NC(=O)N2 +CCc1cc2c(cc1OC)Nc1cc(-c3ccc([N+](=O)[O-])c(OC)c3)ccc1C(=O)N2 +CCS(=O)(=O)Nc1ccc(Oc2ccc(Cl)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +CC1(C)Oc2cc(C(=O)c3coc4ccccc34)cc(O)c2C2CC(O)CCC21 +CCCN(c1c(OC)nn2c(-c3c(OC)cc(COC)cc3OC)csc12)C1CCCOCC1 +CC(=O)n1c2ccccc2c2cc(CN3CCC4(C=Cc5ccccc54)CC3)ccc21 +CN1C(=O)Nc2ccc([N+](=O)[O-])cc2C12NC(=O)NC2=O +CCN(C(=O)CO)C1CN(C(=NC#N)Nc2cccc(OC)c2)N=C1c1ccc(Cl)c(Cl)c1 +Cc1ccc(OCC(=O)NC(=S)Nc2ccccn2)c(Br)c1 +COC(=O)CC1N=C(c2ccc(Nc3ccccc3)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(F)c(CN4CCN(C)CC4)c3)nc2n1 +CCCCS(=O)(=O)NCc1ccc(CC(=O)N(C)C(CN2CCC(O)C2)c2ccccc2)cc1 +CCOC(=O)c1c[nH]c2ncnc(-c3ccc(N4CCS(=O)(=O)CC4)cc3)c12 +COCCN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +O=C1OC2(CCC(CNc3ccc(-c4ncccn4)cn3)CC2)CN1c1ccccn1 +Cn1cc(-c2cc(S(=O)(=O)C(F)(F)F)ccc2NCC2CC2)c2cc[nH]c2c1=O +CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)c(Cl)c2)c(C#N)c1=O +Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C1CCC(C)(O)CC1 +COc1ccc2c(c1NC(=O)C(C)(C)CCCc1ccc(CC(C)C)cc1)OCCC2=O +CC(C)C(C)NC(=O)c1cc(-c2cc3ccccc3n2C)cc(C(=O)NCCc2ccccn2)n1 +Nc1nc(-c2ccc(Oc3ccc(F)cc3)cc2)c2ccccc2n1 +O=C1CCCC(c2cccc3c2OCCO3)N1Cc1cccc(-c2ccccc2)c1 +CCC(CC)(NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(=O)OC +CNc1cc(NS(C)(=O)=O)ccc1Nc1c2cccc(C)c2nc2c(C)cccc12 +CCCCC1(CC(=O)O)OCCc2c1[nH]c1c(Cl)ccc(Cl)c21 +O=C1c2ccoc2CCC1CCN1CCC(c2noc3cc(F)ccc23)CC1 +N#Cc1cc2ccc(N3CCNCC3)cc2n2c1nc1ccccc12 +O=C(Nc1ccc(CCN2CCc3ccccc3C2)cc1)c1cnc2ccccc2c1 +CC(N)CNc1cc2nc[nH]c(=O)c2c(Nc2cccc3cc[nH]c23)n1 +O=C(c1ccc(O)cc1)c1oc2cc(O)ccc2c1-c1cccc2ccccc12 +Cc1nc(-c2nc3c(s2)CN(C(=O)CCc2cccnc2)CC3)cs1 +CN(c1ccc(S(=O)(=O)NC(C)(C)C)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +O=C(c1ccc(F)c(O)c1)c1cccc(-c2ccccc2)n1 +CC(C)CC(NC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)c1)C(N)=O +COc1cc(Nc2cccn(C(C)c3ccc(F)cc3)c2=O)ccc1-n1cnc(C)c1 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+O=C(CN1CCN(Cc2ccc(Cl)cc2)CC1)N1c2ccccc2C2CCCCC21 +Cc1ccn(-c2ccc(C(=O)N3CCC(F)(F)C(=CC(=O)NCc4cnccn4)c4ccccc43)c(Cl)c2)n1 +O=C(CC(NC(=O)c1ccccc1)c1cccc(F)c1)NC(Cc1ccc(F)cc1)B(O)O +NC(CO)(CCc1ccc(-c2coc(-c3cccs3)n2)cc1)COP(=O)(O)O +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1ccnc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)c1C +CCc1nc2cc3c(cc2o1)CCN(CCCSc1nnc(-c2ccc(F)c(F)c2)n1C)CC3 +COC(COc1cccc2ccccc12)CN1CCC(Cc2ccccc2)CC1 +O=C(Cc1ccc(F)cc1)NC(=O)Nc1ccc(Oc2ccnc3[nH]cc(-c4cccnc4)c23)c(F)c1 +Cn1c(CNc2ccc(C(=N)N)cc2F)nc2cc(C(=O)N(CCC(=O)O)c3cc(F)cc(F)c3)ccc21 +CCNC(=O)c1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)cc1 +CNC(=O)c1cc(Oc2ccc3nc(Nc4cccc(OC(F)(F)F)c4)ncc3c2)ccn1 +Nc1nc(N)c(F)c(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)o2)c1F +COc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c4[nH]c(=O)ccc34)cc2)cc1-c1ccccc1 +Cc1sc2[nH]c(=S)n(CCCn3cncc3C)c(=O)c2c1-c1ccccc1 +CN(CCC1CN=C(c2ccccc2)c2ccccc2N1C)C(=O)c1cccs1 +O=C(C=Cc1ccccc1Sc1ccc(Cl)cc1Cl)NCCCn1ccnc1 +COC(=O)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 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+[O-][n+]1nc2c(-n3cccc3)cnn2c2cc(Cl)ccc21 +CCCSc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1cccnc1)CC2 +Oc1ccc2c(c1)C13CCN(CC(F)F)C(C2)C1(O)Cc1cc2ccccc2nc1C3 +CCCCCCNC(=O)CCCn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1 +COCCn1cc(-c2cnc(N)c(C(=O)Nc3ccnc(C)c3)c2)cn1 +CCC1(CC)CC(NC(=O)Nc2ccc3c(c2)NC(=O)CO3)c2cccc(F)c2O1 +CCOn1c(Sc2cc(C)cc(C)c2)c(CC)c(=O)[nH]c1=O +CCOc1ccc2c(NNS(=O)(=O)c3ccccn3)cc(C)nc2c1 +COc1cc2c(Nc3ccc(NC(=O)Nc4ccccc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 +CC(NC(=O)C1COCCN1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 +Cc1ccc(S(=O)(=O)N2CC(=O)NCC2CC(=O)NC2CCCc3cc(CN4CCCCC4)ccc32)cc1 +CCCNC1CCc2c(cccc2CS(=O)(=O)C(F)(F)F)C1 +O=C(C#Cc1ccc2c(c1)OCO2)N1CC2CNCC(C2)C1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1NC(=O)c1cccc(-c2cnn(C)c2)c1 +CCOC1CN(C)CC1NC(=O)Nc1cc2[nH]nc(OC)c2c(CO)n1 +Cc1cc(=O)oc2c(C)c(OC3CCCC3=O)ccc12 +c1ccc2c(c1)CC(Nc1nc(-c3ccsc3)nc3ccccc13)C2 +CN(C)CCNc1cnn(C2CC(C)(C)CC(C)(C)C2)c(=O)c1Br +COc1ncnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12 +Cn1nnnc1-c1ccccc1CNC(=O)Cn1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1=O 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+NCCCC(NC(=O)c1ccc(N(C=O)Cc2cnc3nc(N)nc(N)c3n2)cc1)C(=O)O +Cc1ccc(-n2cc(-c3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)nn2)cc1Nc1nccc(-c2cccnc2)n1 +O=c1n(Cc2nc3ccccc3[nH]2)c2ccccc2n1Cc1ccccc1S(=O)(=O)O +CCOC(=O)c1oc2cnccc2c1Nc1cnc2ccccc2c1 +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccc(C)cc3)nc12 +CCN(CC)C(=O)c1cc2c(OCCC3CCCCN3)c(-c3cc(C)cc(C)c3)c(O)nc2cc1Cl +O=C(O)c1cccc(Nc2cccc(C(F)(F)F)c2)c1 +CCCCCCCCC(SCCCCCC)C(=O)Nc1c(SC)cc[n+](C)c1SC +COc1c(C(=O)NC2CCN(C3CCCCCC3)CC2)cc(Br)c2ccccc12 +CC(C)c1cn2ccccc2c1S(=O)(=O)c1ccc(OCCCNCc2ccccc2)cc1 +Fc1ccc(-c2ccc(-c3cnc4c(-c5nnn[nH]5)cnn4c3C3CCCCC3)cc2)cc1F +O=C(Nc1ccc(-n2cnnn2)cc1)C1CCN(Cc2cc3ccccc3o2)CC1 +Clc1ccc(CN=c2ccn(Cc3ccccc3Cl)c3cc(Cl)ccc23)c(Cl)c1 +COCC1CN(C(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)nc4)ccc3n2)CCN1 +O=C(O)C1CCCC2c3ccccc3CC(CS)C(=O)N12 +Cc1oc2c(cc(NS(=O)(=O)c3ccc4c5c(cccc35)C(=O)N4)c3ccccc32)c1C(=O)OC(C)C +N#CC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1 +CN(C)CC(C)(C)Cn1c(C2CCCCC2)nc2cc(C=CC(=O)NO)ccc21 +CCCCCCC(Sc1nc(Cl)cc(Nc2nc(-c3ccccc3)cs2)n1)C(=O)O +CC(=O)N1CC(c2[nH]c(-c3ccccc3)nc2-c2ccccn2)CCC1c1ccccc1 +COc1cc(C2CCNCC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C2c3cc(Cl)cc(F)c3CC2O)C1 +Cc1ccc2[nH]c(C(=O)N3CCN(C)CC3)cc2c1 +CC(C)(O)CNc1ncc(C(=O)NC2C3CC4CC2CC(O)(C4)C3)c(C2CCC2)n1 +CC(C)(CNC(=O)C1(O)CCCCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +CN(C(=O)c1nccs1)C1CCCN(c2nc(Cl)nc3cc(N4CCOCC4)ccc23)C1 +COc1ccc(CCCCCCCCOc2ccc(CSCc3ccc(C(=O)O)cc3)nc2C=CC(=O)O)cc1 +Nc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)C3CCC(F)(F)C3)CC2)cc1F +CC(C)C(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CC(=O)N1CCOCC1)CC1CCCCC1 +COc1cc(Nc2nc(C)cc(Nc3ccc(Cl)cc3)n2)ccc1-n1cnc(C)c1 +NCCCNc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +Cn1nc2c(c1Cc1ccccc1Cl)-c1nc(Nc3ccn(Cc4ccncc4)n3)ncc1CC2 +NC1CN(c2ccccn2)CCC1c1cc(F)c(F)cc1F +COc1ccc2nc(-n3c(O)nc4c3CCCC4)oc2c1 +CC(C)Cn1c(C(F)(F)F)nc2c1CN(C(=O)CC(N)Cc1cc(F)ccc1F)CC2 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3csnn3)cc2)cc1)C(=O)O +CCSc1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CN(C)c1ccc(C=Cc2sc3ccc(F)cc3[n+]2Cc2ccccc2)cc1 +CONC(=O)c1cn(C)c(=O)c(F)c1Nc1ccc(Br)cc1F +COCc1nc2c(C(=O)NCc3cccs3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +COCn1ccc2cc(C3=NCC(c4cc(OC)c(OC)c(OC)c4)O3)ccc21 +CCn1c(=Cc2scc[n+]2CC)sc(=C2SC3=C(CCCC3)N2C)c1=O +O=c1[nH]c(OCCCOc2ccc(Cl)cc2)nc2ncccc12 +Cc1cc(C)c(S(=O)(=O)NC(Cn2ccc3ncccc32)C(F)(F)F)c(C)c1 +Nc1nc2[nH]cc(Cc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)c2c(=O)[nH]1 +CN1CCN(C2Cc3ccccc3Sc3ccc(-c4ccnn4C)cc32)CC1 +COc1cc(C)c2nc3[nH]nc(C)c3c(C(=O)c3ccncc3)c2c1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)CCCN(CCO)C2 +O=C(O)CC(NC(=O)CCCCCCc1ccc2c(n1)NCCC2)c1cnc2ccccc2c1 +CNc1nc2[nH]c(-c3cccc(CNC(=O)CCOC)n3)cc2c2c1ncn2C +N#CC(C#N)C(C(Sc1ccc([N+](=O)[O-])cc1)=C(O)c1ccccc1)c1cccs1 +CC(C)CCNC(=O)c1cnc(NC(=O)N2Cc3ccccc3C2)s1 +CN1CCC(c2ccc(Cl)cc2)C(c2nc(-c3ccccc3)no2)C1 +CC(C)CC(NC(=O)c1cccc(-c2ccc(Oc3ccc(F)cc3)cc2)n1)C(N)=O +Nc1n[nH]c2cccc(-c3ccc4c(C(=O)Nc5cccc(C(F)(F)F)c5)cccc4c3)c12 +CC1(c2nc(NC(=O)c3ncc(C(F)F)cc3N)ccc2F)N=C(N)OCC1(F)F 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+Cc1cc(C)n(-c2nc(NC(C)C)nc(NC(C)(C)C)n2)n1 +O=C(O)Cc1ccc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1 +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OCCNS(=O)(=O)c2cccs2)c1 +CC(NP(=O)(OCC1C=CC(n2cnc3c(N)ncnc32)C1)Oc1ccccc1)C(=O)OC(C)(C)C +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2Cc3n[nH]cc3C1c1c(F)cccc12 +COc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(N3CCCC3)c2c1 +C1=C(c2ccccc2)CCC(CCN2CCN(c3ccccn3)CC2)C1 +CCCC1CCN(C2C=C(C(=O)O)CC(N)C2NC(C)=O)CC1 +COc1ccc(CCCCN(C)CCOc2cc(F)cc3c2OCCC3=O)cc1 +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C)c3)cn2CCN(CC)CC)CC1 +C=CC(=O)NCCCCC(NC(=O)OCc1ccccc1)C(=O)NCC(=O)O +Cc1ccc(F)cc1OC1CN(C(C)c2nc3c(cnn3C3CCOCC3)c(=O)[nH]2)C1 +CCCCCCCNC(=O)Oc1ccc2c(c1)CN(C)C(c1ccsc1)N2C +CCC(N)(C#Cc1nc(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)cc1C#N)CC +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)N1CC2CC1CN2 +COc1ccc2cc(S(=O)(=O)NN(Cc3cccc(C(=N)N)c3)C(=O)N3CCCCCC3)ccc2c1 +CC(=O)Nc1cccc(Nc2ncnc(N3CCC(OCc4ccc(C)cc4)CC3)n2)c1C +CCC(CC)OC1C=C(C(=O)O)CC(NC(N)=NC)C1NC(C)=O +O=C(NCCCCc1ccccc1)Nc1ccc2ncc(-c3ccc(O)c(F)c3)nc2n1 +CC(C)(C)C(=O)c1c[nH]c2ncc(Nc3ccc(C=C(C#N)c4nccs4)cc3)nc12 +O=C(OCCCC1CCc2ccccc2N1S(=O)(=O)c1ccc(Cl)cc1)N1CCC(N2CCCCC2)CC1 +CS(=O)(=O)NC(=O)CCc1ccc(-c2c(C=Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cc1 +O=C(CCCNc1ccccn1)Nc1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2)C(=O)O)cc1 +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NCc1ccc(C(=O)O)cc1 +Cc1c(-c2cccc(Cl)c2)nc(O)n1C1CCN(Cc2ccccc2)CC1 +O=c1sn(-c2cccc(C(F)(F)F)c2)c(=O)n1Cc1ccc(F)cc1 +Fc1ccc(-c2n[nH]c3cc(C(F)(F)F)cnc23)cc1F +N#Cc1c(-c2ccc(C(F)(F)F)cc2)cc(N2CCNCC2)n2c1nc1ccccc12 +COc1cc(-c2ccc3c(c2)NC(=O)C3=Cc2cc(C(=O)NCCCn3ccnc3)c(C)[se]2)ccc1O +Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)c3ccc(NC(=O)c4ccncc4)cc3n2)cn1 +N#Cc1ccc2c(c1)CC1C2CCCN1C(=O)c1ccc2[nH]cnc2c1 +CN(C)C1CCN(CC2CCC(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(Cl)c(O)c(Cl)c5)cc34)CC2)C1 +CCNc1cc(-n2nc(C(C)C)c3c(-n4cnc(-c5cnn(C)c5)c4)ccnc32)ccc1C(N)=O +Cn1c2cc(CCCCN3CCCC3)c(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +O=C(Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1)Nc1cccc(OC(F)(F)F)c1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCC(C(=O)O)CC2)C1=O)c1ccccc1 +Cc1c(Cc2ccccc2)c(=O)on1C(=O)N1CCCCC1 +CN(C)C(=O)CN1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc21 +CCn1cncc1C(OC)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(-c3ccccc3)c1)cc(=O)n2C +COc1ccc(Cc2ccc(OC)c(OC)c2OC)cc1[N+](=O)[O-] +Cc1ccc2nc(C)c(-c3cc4nc(N5CC(O)C5)cc(NC5CCOCC5)n4n3)nc2c1 +CCc1cc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)nn1CC(C)C +CCN(CC)c1ccc(C=NNC(=O)Cn2nnc3ccccc32)c(O)c1 +Cc1cc(C)cc(Sc2c(CN3CCCCC3)c(C)[nH]c(=O)c2I)c1 +CN(C)C1CCN(c2ccc(-c3coc4cc(-c5ccc(OC(F)(F)F)cc5)ccc4c3=O)cn2)C1 +Nc1nnc(-c2ccc3[nH]cc(-c4cccc(N5CCOCC5)n4)c3c2)o1 +CC(C)(C)C#CC=CCN(c1cccc2c1CCC(=O)N2)S(C)(=O)=O +CC1c2nnn(-c3cnccn3)c2CCN1C(=O)c1ccc(Cl)cc1Cl +CCN1CCC(c2ccccc2)=C(C(=O)OCCc2ccccn2)C1 +CCCSc1nc2cc(-n3nc(C)n(C(F)F)c3=O)c(F)cc2s1 +C[N+](C)(C)CCOC(=O)C(c1ccccc1)c1ccccc1 +N#Cc1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCc4ccc(F)cc4)c3)C2)cc1 +O=C(NO)C1Cc2ccccc2CN1S(=O)(=O)c1ccccc1 +CS(=O)(=O)c1ccc(C2CN3CCCC3c3ccccc32)cc1 +COc1cc(C2C3=C(COC3=O)Nc3cc4c(cc32)OCCO4)cc2c1OCO2 +Cc1c(N(CCOC(C)(C)C)S(=O)(=O)c2ccc(C(=O)O)cc2)sc2ccccc12 +CC(C)c1nc2ccccc2n1Cc1ccc2c(-c3ccc(F)cc3)cc(C(N)=O)nc2c1 +Cc1cc(C2CCN(CCO)CC2)cc2[nH]c(-c3c(NCCn4cc(Cl)cn4)cc[nH]c3=O)nc12 +Nc1nc2c(cnn2CCc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)c2nc(-c3ccco3)nn12 +O=C(Nc1ccc(Cl)cc1)c1ccc2cc3n(c2c1)CCCNC3=O +O=C1CC(c2cccc(-n3ccnc3)c2)=Nc2ccc(C#Cc3ccccc3F)cc2N1 +O=C(Cc1c(-c2ccc(Cl)cc2)nc2ccc(Cl)cn12)N1CCCCC1 +Cc1ccc(Sc2cncc3sc(C(N)=O)cc23)c(C)c1 +O=C(O)CCC(=O)NC(CC(=O)O)Cc1ccc(-c2ccccc2)cc1 +O=c1cc(-c2ccoc2)oc2cc(O)c(O)c(O)c12 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc(O)c(Br)c1 +Cc1cn(-c2cccc(-c3c[nH]c4ccc(-c5nnc(N)s5)cc34)n2)cn1 +CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCCN2CCCC2=O)cc1Oc1ncc(C(F)(F)F)cc1Cl +CSc1nn2cc(-c3nc4ccc(OCc5ccccc5Cl)cc4o3)nc2s1 +Cc1cc(C)cc(-c2nc(C(F)(F)F)n(CCC(O)CC(O)CC(=O)O)c2-c2ccc(F)cc2)c1 +CCCCC1CN(CC2CCOCC2)C(=O)OC12CCN(C1CC3CN(C(=O)c4c(C)ncnc4C)CC3C1)CC2 +CCNC(=O)c1c(-c2ccccn2)c(-c2ccc(F)cc2)c(CCC(O)CC(O)CC(=O)O)n1C(C)C +COc1ccc(C(Cc2ccc(Cl)cc2)NCC(O)Cc2ccc(O)c(NS(C)(=O)=O)c2)cc1OC +OCC1OC(n2cnc3c(SCc4ccc(OC(F)(F)F)cc4)ncnc32)C(O)C1O +CC(=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccccc4OC(F)(F)F)nc23)N1 +CCOc1ccc(OS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +Cc1nnc2n1-c1ccc(-c3cncc(C(C)(C)O)c3)cc1CC2 +Cc1cccc(C)c1N1CC(CN(C)C(C)C)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)C(C)C1=O +CN1C(=O)N2C(=NCC2CN2CCN(c3ccccc3Cl)CC2)c2ccccc21 +NC1CCC(CNC(=O)C2CCCN2C(=O)C(Cc2ccccc2)c2ccccc2)CC1 +O=C1c2ccccc2CCC1CN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +O=C(Nc1ccc(C(=O)N2CC3CSCCN3Cc3ccc(F)cc32)cc1)c1ccccc1-c1ccccc1 +CC(C)=CCc1cc(O)c2c(=O)c3cccc(O)c3oc2c1O +Cc1c(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nn4)CC3CO2)ccc(F)c1C#N +NC(=O)c1ccc(-c2ccc3[nH]nc(-c4cncc(OC5CNCCC56CC6)n4)c3c2)c(F)c1 +COc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3cc(Cl)ccc32)ccc1OCCN1C(=O)CN(C)C1=O +Cn1cc(-c2cc(C(N)=O)nc3cc(Cc4cc(Cl)nc(C(F)(F)F)c4)ccc23)cn1 +COc1cccc(C2=CCC(N3CCN(c4ccccc4)CC3)CC2)c1 +COc1cccc2c1CCCC2CCCNCC(=O)NC1CCCCC1 +CCC(=O)C1OC(n2cnc3c(N)nc(C#Cc4ccccc4)nc32)C(O)C1O +Cn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2-c2ccc(F)c(F)c2)CC1 +Brc1cc(Br)c2c(c1)C(NCCCNc1nc3ccc[nH]c-3n1)CCN2 +CC1(C)OCC(COc2ccc(F)cc2C2CCCN2c2ccn3ncc(C(N)=O)c3n2)O1 +CNc1nn2c(C)ccnc2c1S(=O)(=O)c1ccccc1 +Cc1cccnc1CN1CCC2(NC(=O)N(c3ccc(-c4ccccc4)cc3)C2=O)C(C(=O)O)C1 +CCCOCCn1c(=O)nc(NCCO)c2nnc(-c3ccc(OC)nc3)cc21 +O=C(Cc1ccc(F)cc1)NN=C1C(=O)Nc2ccc(C(=O)N3CCC(NC4CC4)CC3)c(Cl)c21 +CCOC(=O)C1CCCN(CCCCCCOc2ccc3oc(-c4ccccc4)cc(=O)c3c2)C1 +CCC(COC)NC(=O)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +CC(Oc1cc(-c2cc(-c3cc(CN(C)C)cs3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F +NC(=O)c1ccc(N2CCC(CCc3ccccc3)C2)c2cncnc12 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncccn2)c1 +C#Cc1cccc(Nc2cc(C)nc3ccc(NC(=O)Nc4ccc(N(CCCl)CCCl)cc4)cc23)c1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)C3CCC3)cs2)CO1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cnc(N)nc1 +COc1cc(O)ccc1C=CC(=O)OCCc1ccc(O)cc1 +CCOC(=O)c1ccc2[nH]c3c(OC)c4[nH]c5ccc(C(=O)OCC)cc5c4cc3c2c1 +Cc1cccc(-c2[nH]c(CNc3ccc(CC#N)cc3)nc2-c2ccc3ncnn3c2)n1 +CON(C)C(=O)C1C2CC3CCC1N3CC2=Cc1ccc(Cl)c(Cl)c1 +O=C(O)CCc1ccc(OCc2nc(-c3ccc(F)cc3)no2)cc1 +COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(C)cc3c2C)c(S(C)(=O)=O)c1 +O=C(Nc1ccc(F)c(-c2nc3cc(-c4ccccc4)cnc3[nH]2)c1)N1CCCC1 +CC(NC1CCCc2c1[nH]c1ccc(Br)cc21)c1ccccc1 +O=C(NC(Cc1nc2cc(Cl)ccc2[nH]1)C(=O)O)c1cc2ccccc2s1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CCCC1CC(C(=O)O)C2 +CCCN1C2CCC1CC(=C(c1ccccc1)c1ccc(C(=O)N(CC)CC)cc1)C2 +CCC1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2cc3cccc(F)c3nc2-1 +Nc1ncncc1-c1ccnc2c(-c3ccc(F)cc3Cl)csc12 +Cc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(OCc3ccccn3)cc1)CC2 +Cc1ccc(C(N)=O)cc1Nc1ncnn2cc(C(=O)c3ccccc3)c(C)c12 +CC(C)NC(=O)c1ccc(CN(C2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 +Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCc1ccncc1 +COc1ccc(C(NC(=O)c2cc(F)c3cnc(NCC4CC4)nc3c2)c2cnn(C)c2)cc1F +CCCCCCCN=c1ccn(Cc2ccccc2)c2cc(Cl)ccc12 +CNC(=O)c1c(NCC2CCC3(CCC3)CC2)nc(C#N)nc1OCCC1CCN(C)CC1 +CC1NC(=O)c2cc3ccc(C(=O)Nc4cnn(C)c4)cc3n2C1C +Fc1cccc(-[n+]2nc(-c3ccc(OCc4ccccc4)cc3)nn2-c2ccccc2)c1 +Cc1cnc2[nH]cc(C(=O)Nc3cncc(C(=O)c4cn(C(C)C)c5ncncc45)c3)c2c1 +CCOC(=O)N1CCC(N2CCC(C3(c4ccc(S(=O)(=O)c5ccc(OC)cc5)cc4)SCCCS3)CC2)CC1 +Cc1noc(C)c1CN1CCC(CCOc2ccc(-c3cc4c(ncn4C)c(C#N)n3)cc2C(F)(F)F)CC1 +O=C(Cc1ccccc1C(F)(F)F)N1CCC(c2cc(-c3ccc(F)cc3)nn2-c2ncccn2)CC1 +CC(C)NC(=O)c1sc2nc3c(c(-c4cccs4)c2c1N)CN(C)CC3 +CC(C)(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)cc1 +CCCCCN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCNCC2)cc1 +Nc1cncc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1 +COc1cc2c(cc1OCCN(C)C)Cc1c-2n[nH]c1-c1ccc(-c2ccc(O)cc2)cc1 +O=C(C=Cc1ccc(-c2ccc(Cl)cc2)cc1)Nc1ccc(CN2CCCCC2)cc1 +COc1ccc2c(c1)C1(CC1c1ccc3c(C=Cc4ccc(CN5CC(C)OC(C)C5)cc4)n[nH]c3c1)C(=O)N2C +O=C(Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1)N1CCN(c2cccc(Cl)c2)CC1 +Cc1c(-c2cn(C(C)C)cn2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +O=C(CCCc1cccs1)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CCCCCCC(=NOCCCCC(=O)O)C(Cc1ccccc1)n1ccnc1 +Cc1ccccc1C(Oc1cc(OCc2ccsn2)ccc1C#N)C(=O)O +CC(C)(C)C12COC(c3ccccc3N=C=S)(OC1)OC2 +O=C(NC(Cc1ccc(OCCc2ccc3c(n2)NCCO3)cc1)C(=O)O)c1c(Cl)cccc1Cl +COC1=CC(c2ccc[nH]2)=NC1=Cc1[nH]c(Cc2ccc(F)cc2)cc1Cc1ccc(F)cc1 +O=C(Nc1n[nH]c2nnc(-c3cccc(F)c3F)cc12)C1CCCC1 +CC(O)c1nccc(N2CCN(c3cnc4cc(Cl)c(Cl)cc4n3)CC2)n1 +O=C(c1ccc(C(=O)N2CCN(c3ccc(OC4CCN(C5CCC5)CC4)cc3)C(=O)C2)cc1)N1CCC1 +O=C(C=Cc1ccc(Sc2cccc(OC3CCNCC3)c2)c(C(F)(F)F)c1C(F)(F)F)N1CCOCC1 +CCC(C1=C(CCN(C)C)Cc2cc(Cl)ccc21)c1ccccn1 +O=[N+]([O-])c1ccc(Oc2cccc(N(Cc3cccc(OC(F)(F)C(F)F)c3)CC(O)C(F)(F)F)c2)cc1 +COc1ccc(C#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCOCC1)C2=O +COc1ccc(-c2nc(NCc3ccc4c(c3)OCO4)ncc2C(=O)NCCOc2ccccc2)c(OC)n1 +NC(=O)c1cccc2c1C(=O)N(CC1CCN(Cc3ccc(F)cc3)CC1)C2 +C#CCOc1cnc(C(=O)Nc2cnc(F)c(C3(C)CC(C(F)(F)F)OC(N)=N3)c2)cn1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4ccc(-c5ccccc5)cc4)nc31)C(O)C2O 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+COC(=O)c1ccc(CCc2c(C(=O)O)[nH]c(=O)[nH]c2=O)cc1 +CC(Cc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1)C(=O)O +O=C(O)c1ccc2ccc(C=Cc3cn4nc(Cl)cc(N5CCOCC5)c4n3)nc2c1 +NCCCCCCCCCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +CCOc1ccccc1C1C(C#N)=C(N)Oc2cc(N(C)C)ccc21 +Cc1cc2nc(CN(C)Cc3ncccc3C)[nH]c2cc1C +Nc1ncnc2c1c(C(=O)c1ccc(NS(=O)(=O)c3c(F)cccc3F)cc1)cn2C1CCCC1 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C(C)(C)C)cc4)CC3)c2cc1OCCOC +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1ccccc1Cl +CC(C)(C)c1ccc(N(C(=O)CCC(=O)Nc2ccc(-c3ccc(OCC(=O)O)cc3)cc2Cl)C2CC2)c(Cl)c1 +O=C(O)c1ccc(-c2ccnc(Nc3ccccc3)n2)cc1 +CCCN(CC1CCCC1)C(=O)c1cc(Cl)cc(OCCCON=C(N)N)c1 +COc1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1OC +CN(C)N=C1SC(=Cc2ccc(O)c(Cl)c2)C(=O)N1c1ccccc1 +CC(NC(=O)C(Cc1cccc(C#N)c1)NC(=O)C(C)(C)N)c1nc2cc(Cl)c(Cl)cc2[nH]1 +O=C(NCC1(c2ccc(Cl)cc2)CCOCC1)c1cccc(Cl)c1F +CC(C)CC(CC(=O)OCC1(CO)CC(=Cc2cccc(C(=O)O)c2)C(=O)O1)CC(C)C +Cc1cc2c(cc1C(OCc1ccccc1F)c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CCC(O)C3)no2)cc1C#N +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)cn4)CC3CO2)c1C +COc1cc2ccn(C3OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C3O)c(=O)c2cc1F +CCC(C)C(CN(CC(=O)NC(CCSC)C(=O)O)Cc1cccc2ccccc12)NC(=O)CCCCc1ccccc1 +CCCN(C(=O)OCc1ccccc1)C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2cccc(Cl)c2)CC1 +O=C(O)c1csc(-n2nc(-c3cc(F)cc(F)c3)cc2O)n1 +CC(CF)Nc1ncc2c(n1)CN(C(=O)NC(CO)c1ccc(Cl)c(Cl)c1)CC2 +CNc1nc(NCc2ccc(NC(=O)C3CCN(Cc4ccccc4)CC3)cc2)c2ccc(C)cc2n1 +COc1ccc(S(C)(=O)=O)cc1CC(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C +CN1CCC(c2coc3ccc(NC(=O)c4c(F)cccc4Cl)nc23)CC1 +O=C(Cc1cccs1)Nc1cccc(C(=O)C(=O)c2ccccn2)c1 +CN(CCCc1ccc(F)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CCNCC2)n1 +CCN(CC)CCOc1cccc(Nc2nnc3cc(-c4c(C)cccc4C)cc(C)c3n2)c1 +Nc1ncnc2c1ncn2C1OC2CC(CC(=O)O)(C(=O)O)OC2C1O +CC(C)C(CO)NCc1nc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)ccc1F +COc1cccc(-c2ccc(C#N)c(C(F)(F)F)c2)c1 +CC(=O)N1CCN(c2nncc3cc(-c4c(C)ccc5c(NC6CC6)noc45)ccc23)C(C)C1 +COCC1CC2CSC(N)=NC2(c2cc(C#N)c(F)cc2F)CO1 +CN(CC(=O)N(C)C(CN1CCCC1)c1ccc(-c2ccccc2)cc1)c1ccc(Cl)c(Cl)c1 +Cc1nn(CC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)c(C)c1Cl +c1cc(C2=NCCN2)ccc1OCCCOc1ccc(C2=NCCN2)cc1 +Oc1ccc2c3c(sc2c1)-c1ccccc1OC3c1ccc(OCCN2CCCCC2)cc1 +CNC(=O)C(NC(=O)C(CC(C)C)C(O)C(=O)NO)C(C)(C)C +Cc1ccc(-n2nccn2)c(C(=O)N2CCOCC2Cc2cccc(-n3cccc3)c2)c1 +CC(Nc1c(F)ccc(F)c1F)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cn(C)cn1 +N#Cc1ccc(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)nc1 +Nc1nc(-c2ccco2)nc2sc(CN3CCC(F)(F)CC3)cc12 +CC1(C(=O)NC(Cc2ccncc2)C(=O)O)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Cc1[nH]c2ccccc2c1C=Cc1cc(N)c2ccccc2[n+]1C +C=CC(=O)Nc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OCCNC(=O)CN(C)C +CC(=O)c1csc(CNC(=O)C2C(C(=O)NCCCN(C)C)C3C=CC2C32CC2)n1 +NC(=O)c1cccc2c1C(=O)N(C1CCN(Cc3ccsc3)CC1)C2 +CONC1CCC(NCC(O)C(Cc2cc(F)cc(F)c2)NC(C)=O)(c2cccc(C(C)(C)C)c2)CN1 +CCOC(=O)Cn1nc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)c1C(F)(F)F +COc1ccc2c(c1)CCC(O)C2=Cc1cc(OC)c(OC)c(OC)c1 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+Cc1ccc(CN2Cc3nc4ccccc4c(-c4ccccc4)c3C2=O)cc1 +CN(C(=O)Cn1c(=O)oc2cccc(-c3ccccc3)c21)c1ccccc1 +CCS(=O)(=O)NCc1noc(C(CCCC2CCCCC2)CC(=O)NO)n1 +FC(F)(F)c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2[nH]cnc2c1 +CC(C)CC(NC(=O)c1ccco1)C(=O)NC1CCC(C)N(S(=O)(=O)c2ccccn2)CC1=O +CCN(CC)C(=O)c1ccc(C(=Nc2ccccc2Cl)N2CCN(CCc3cccs3)CC2)cc1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)Cc2ccccc2C(=O)O)c1=O)C(=O)C(F)(F)F +C[N+]1(C)C2CC(OC(=O)C(O)(c3cccs3)c3cccs3)CC1C1OC12 +O=C(c1ccc([N+](=O)[O-])cc1)c1nccc2c1[nH]c1ccccc12 +COc1ccc2c(c1)OCCCC=CCCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +Cc1c(C#N)cccc1C1CN2CCN(C(=O)Cc3cnc(-n4cnnn4)nc3)CC2CO1 +O=C(O)c1ccccc1NS(=O)(=O)c1cccc(-c2cnn(Cc3ccc4ccccc4c3)c2)c1 +COc1cc2nc(N3CCC(OCCO)CC3)nc(N)c2cc1OC +CCCCN1CCN2c3c(cccc31)C1CN(CCCC(=O)c3ccc(F)cc3)CCC12 +CC(C)(C)c1cc(NC(=O)C2CCCN2C2CCCCC2)no1 +NC(=S)Nc1ccc2c(c1)Cc1cc(N(Cc3ccccc3)Cc3ccccc3)ccc1-2 +CCCCC1(CC)CS(=O)(=O)c2cc(CCC(=O)NC)c(OC)cc2C(c2ccccc2)N1 +CCN1c2ncc(CSc3ccccc3)cc2C(=O)N(C)c2ccc(Cl)nc21 +COc1ccc(CN(C)CCCCc2ccc(NC(=O)c3cccc4c(O)c5cccc(N)c5nc34)cc2)cc1OC +CC(C)(C)CC(O)C(=O)Nc1sc2c(c1C(N)=O)CC(C)(C)OC2(C)C +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(C2CCCCC2)sc2cc(O)ccc12 +NCCCn1c2c(c3ccccc3c1=O)C(=O)c1ccccc1-2 +Cc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)N3CCN(c4ccccn4)CC3)cc1)C2 +COc1ccc2c(c1)c1c(n2C)CCCC1NC(=O)C1CC1 +CCc1cc(O)ccc1-c1ccc2c(C(N)=O)n[nH]c2c1 +CC(C)CC(NC(=O)c1cccc(S(=O)(=O)CC(C)C)n1)C(N)=O +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3cc(F)cc(F)c3)CC2)cc1 +CCc1cc2c(cc1NC(=O)CN1CC3CN(C)CC3C1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +COc1ccc(C2(O)CCC(NC3CCN(C(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cn1 +CC(C)Oc1cccc2c1CCCC2Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O +CCN(CC)CCn1cc(-c2ccc(F)c(C)c2)nc1C1CCN(c2ncnc(N)c2C#N)CC1 +O=C(Nc1ccc2ncccc2c1)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +COc1ccc(-c2cc(=O)n(Cc3cccnc3)nc2-c2ccc(OC)cc2)cc1 +Nc1ccnc(N2CCC(n3c(=O)n(-c4ccccc4)c4cccnc43)CC2)c1 +COCC(CO)NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 +COC(=O)c1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)NC(C)(C)C)CC3)c2)c1 +O=C(O)C1=Cc2cc(Cl)cc(Cl)c2OC1C(F)(F)F +CCCSc1nc(N2CCC(C(=O)O)CC2)ccc1C(=O)NC1CCCCC1 +O=C(Nc1ccc(Cl)cc1)C1CN(C(=O)c2cc(F)cc(-c3ccncc3)c2)CC(F)(F)C1 +CCn1c(=O)cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc21 +COc1ccc(-c2oc(O)nc2-c2cc(OC)c(OC)c(OC)c2)cc1O +Cc1[se]c(C=C2C(=O)Nc3cc(-c4ccc(O)cc4)ccc32)cc1C(=O)NCCN1CCCC1 +CCC(CC)n1c(CNC2CCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CN(c1cccc(Cl)c1)c1nc2cc(C(=O)O)ccc2c2cnccc12 +O=C1Nc2ccc(F)cc2C(C#CC2CC2)(C(F)(F)F)O1 +CCC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc(F)cc3)n[nH]c2C1(C)C +O=C(Nc1ccc(-c2nnc(NCCCN3CCOCC3)o2)cc1)c1ccccc1F +CCc1ncnc(N2CCCCC2)c1C#Cc1ccc(NC)nc1 +COC(=O)OCC1C2CCC(C)C1(C)CCC(C)=CCCC1(C)OC1C2=O +c1ccc(Nc2ccc(Oc3nccnc3N3CCCCC3)cc2)nc1 +CNc1ncc(C(=O)Nc2cc(C(=O)Nc3cccc(C(F)(F)F)c3)ccc2C)c(Oc2ccccc2)n1 +Cc1nc2c(C)cccc2c(Nc2ccc(N3CCCN(C)C3)cc2)c1C +CC(=O)NC(C)c1ccc(OC2CCN(c3cccc(C(F)F)n3)C2)cc1 +CS(=O)(=O)C1(c2nc(-c3cccc4[nH]ccc34)nc3c2OCC2COCCN32)CC1 +ON=Cc1ccc(-c2ccccc2)c(-c2ccccc2)c1O +CCCNC(=O)Nc1cccc(-c2ccc(CC(NS(=O)(=O)CC34CCC(CC3=O)C4(C)C)C(=O)O)cc2)c1 +CC(C)n1c(O)nc2ccc(-c3cccc(Cl)c3)cc21 +O=C(c1nc2c(N3CCNCC3)cccc2[nH]1)c1cccc2ccccc12 +CN(C)c1ccc(-c2cc3onc(-c4ccccc4)c3c(=O)n2C)cc1 +CC(C)(C)C(NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(N)=O +CCCCN1CCC(C(=O)NO)(S(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CC1 +Cc1ccc2cc(Cn3cc(C(=O)NCc4c(Cl)cc(N)nc4C)nn3)ccc2n1 +CNCc1ccc(C2=NOC(c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)C2)cc1 +CN(C)c1ccc(C2=NN(c3ccc(S(=O)(=O)NC(=S)NC4CCCCC4)cc3)C(c3ccccc3)C2)cc1 +COc1cc(S(=O)(=O)c2ccc3sccc3c2)cc2c3c(oc12)CCNC3 +OC(CNCCCCCCN1CCC(c2ccc(F)cc2)C(COc2ccc3c(c2)OCO3)C1)COc1cccc2[nH]ccc12 +COCCN1CCN(c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)CC1C +O=C(O)c1cc(NC(=O)c2nc3ccccc3nc2Oc2ccc(OC(F)(F)F)cc2)ccn1 +CC(C)C(NC(=O)Cn1ccc2c(=O)n(CC(=O)c3ccccc3)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +COc1cc(CC2C(O)C(O)C(Cc3cc(OC)cc(OC)c3)N(CC3CC3)C(=O)N2CC2CC2)cc(OC)c1 +NCCCCC(NC(=O)c1ccc(F)c(F)c1)C(=O)c1noc(Cc2ccc(C(=O)NCCc3cccc(Cl)c3)cc2)n1 +OC1CCN(c2nc(N3C4CCC3COC4)c3c(-c4ccccc4Cl)csc3n2)C1 +CC1CC(N)CC(c2ccncc2NC(=O)c2nc(-c3cc(O)ccc3F)ccc2F)C1 +O=C(NCc1ncc(-c2ccc(Cl)c(Cl)c2)[nH]1)Nc1ncc(Sc2ccccn2)s1 +COCCN1CCc2ccc(Nc3ncc(Cl)c(NC4CCCCC4NS(C)(=O)=O)n3)cc2CC1 +Cn1c(OC2CCN(c3ccc(-c4ccncc4)cc3)CC2)nc(-c2ccncc2F)cc1=O +N#Cc1c(N)nc(OCc2ccnc(C(=O)NC3CC3)c2)c(C#N)c1-c1ccccc1 +Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NCC2CC2)cn1 +COC(=O)C(C#N)(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 +O=C(O)CC1CC(C(F)(F)F)CN1c1ccc(Oc2ccccc2OC(F)(F)F)cc1 +CC1(C)CC(CCNc2ccc(Cl)c(F)c2)(c2ccccc2)CCO1 +CNC1=C(N(Cc2ccc(Cl)c(Cl)c2)C(C)=O)C(=O)c2ccccc2C1=O +Cc1nc(C)c(CNc2nc(OCC3CC3c3ccc4ncccc4n3)ncc2C)s1 +CCOC(=O)Cc1c(N)nc(N)n(CCOCP(=O)(O)O)c1=O +CN1CCC2(CC1)CC(=O)c1cc(C=CC(=O)NO)ccc1O2 +COc1ccc(NC2=CC(=O)c3sc(C)nc3C2=O)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2ccnc(N(C)C(C)C)n2)cc1 +COCCCNc1ccc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)cn1 +CCc1cccc(NC(=O)c2cc(Cl)c(C3(C)CS(=O)(=O)C4(CCCCC4)C(=N)N3)s2)n1 +CN(C)C(=O)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21 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+Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(NC3CCC(N)CC3)c2c1=O +CCCCCCCCCCn1ccc(=O)c(Cc2c(Cl)cccc2Cl)c1C +NC(=O)c1cc(-c2ccc(OC(F)F)cc2)c2ccccc2n1 +CC1=NCC2CNC(c3ccccc3Cl)c3cc(Cl)ccc3C2=N1 +O=C1OCC2CCCC2N1c1ccc(C#Cc2cccc(F)c2)cn1 +CCc1nccc(-c2ccc(C(=O)N3CCN(C(C)(C)C)CC3)c(F)c2)c1C#Cc1ccc(NC)nc1 +CCOC(=O)c1cn2ncnc(Nc3ccc(F)c(C(=O)NOC)c3)c2c1C(C)C +COc1ccc(CCNc2cc(-c3ccc(N(C)C)cc3)nc(OC)n2)cc1 +O=S1(=O)c2ccccc2CN1c1cccc(Oc2ccccc2)c1 +CC(=NNC(=O)c1cccc(N)c1)c1cccc(Cl)c1 +O=C(COc1ccc(Cl)cc1)NNC(=S)NCCCCC1CCCCC1 +NCc1ccc(Cl)cc1CNC(=O)C1CCCN1C(=O)C1COc2ccccc21 +Fc1ccc(OC(c2cccc(F)c2)C2CCNCC2)cc1 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(N)cc23)C1(C)C +Cn1c(Nc2c(Cl)ccc(CNC(=O)OC(C)(C)C)c2Cl)nc2cc(C(=O)NCC(F)(F)F)c(OCC(F)F)cc21 +COc1ccc(OC)c(CCNC(=S)Nc2ccc(Br)cn2)c1 +C#Cc1ccc2[nH]c3cnc(C(=O)OC(C)(C)C)cc3c2c1 +CN1CCCC(CN(C)C(=O)Cn2c(-c3ccccc3)c(C3CCCCC3)c3ccc(C(=O)O)cc32)C1 +CN(Cc1ccccc1Cl)C(=O)n1cnc(S(=O)(=O)C2CC3CCC2C3)n1 +CC(C)N1C(=O)C(NC(=O)C(Cc2ccccc2OC(F)(F)F)NC(=O)OC(C)(C)C)CCc2cc(F)ccc21 +COc1ccc2c(=O)c3c([nH]c2c1)CCC(F)(F)C3 +Cc1ccc2[nH]cc(C(=O)c3ccccc3NCc3ccc4cn[nH]c4c3)c2c1 +COc1cccc2oc(C(=O)Nc3ccc(-c4ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc4)cc3)cc12 +O=C(Nc1ncnc2[nH]cnc12)c1cccc(-c2cccc(-c3c[nH]cn3)c2)c1 +Cc1nc2ccc(I)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)nc3)cc12 +CCN(CCCCNC(=O)COc1ccc(-c2cc(=O)c3c(OC)c(OC)c(OC)cc3o2)cc1)Cc1ccccc1OC +CCCCCCOc1ccc2c(c1OC)CN1CCc3cc(OC)c(O)cc3C1C2 +Cn1cnc(C(=O)N2CCN(C(=O)c3ccc(Nc4nc5ccccc5n5nnnc45)cc3)CC2)c1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2Cc3ccccc3CC2C(=O)O)c1 +O=C1N(c2cc(Cl)nc(Cl)c2)CCN1c1cnccc1C1CC1 +COc1ccc(-c2cc(CNc3nccc(Nc4cc(C5CC5)[nH]n4)n3)on2)cc1 +OCC1OC(n2c(Nc3ccccc3)nc3c(N4CCc5ccccc54)ncnc32)C(O)C1O +CC(C)(C)c1cc(NC(=O)Nc2ccc(F)cc2)no1 +Cc1cc(OCCCc2c(C(=O)NS(=O)(=O)CCNC(=O)c3ccc(F)cc3)[nH]c3ccccc23)cc(C)c1Cl +CC(NC1=NC(=O)C(C)(C(C)C)S1)c1ccccc1C(F)(F)F +O=C(O)c1cc2cc(O)ccc2n1Cc1ccc(Cl)c(Cl)c1 +c1ccc(C2CCc3cc(Oc4ncc(CNC5CC5)s4)ccc3O2)cc1 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+Cc1cc2ccccc2nc1-c1ccc(N(Cc2cccc3ccccc23)C(=O)c2ccc(O)cc2O)cc1 +O=C(Nc1ccc(C(=O)N2CCN(CCOCCO)CC2)cc1)N1Cc2ccccc2C1 +Cn1cc(-c2cc(C(N)=O)nc3cc(CN4CC(C(F)(F)F)OC(C)(C)C4)ccc23)cn1 +CC(CS)C(=O)NC(CSCc1ccc(I)cc1)C(=O)O +Nc1ncnc(Nc2ccc3c(cnn3Cc3cccc(F)c3)c2)c1C=NNCC(F)(F)F +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)Nc1ccccc1C(=O)NCc1ccc2c(c1)OCO2 +Cc1cscc1-c1noc2cnc(NC(C)c3ccccc3)cc12 +Cc1ccccc1N=C(N)NC12CC3CC(C)(CC(C)(C3)C1)C2 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1c(F)cccc1F)C(C)O +COc1ccc(Cl)cc1NC(=O)C1c2ccccc2C(=O)N(CC(C)C)C1c1cccs1 +CCn1c(NC(C)C)nc2c(C3CCN(c4ccccn4)CC3)csc2c1=O +NC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(OC(F)(F)F)c3F)CC3CC32)c2ccncc12 +O=C1CC(c2c[nH]c3ccccc23)C(=O)N1CCCN1CCC(c2c[nH]c3ccccc23)CC1 +CNc1nc(Nc2ccc(C(=O)N3CCC(C#N)CC3)cc2OC)ncc1Br +N#Cc1cc(-c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)ccn1 +O=C(Cc1ccc(Cl)c(Cl)c1)N1CCC(O)CC1CN1CCCC1 +COc1cc(C2NC(=O)NC(C)=C2C(=O)O)ccc1OCCOc1cc(C)nc2ccccc12 +CNC(=O)C(CC(C)C)NC(=O)c1cccc(-c2cccc(C(F)(F)F)c2)n1 +COC(=O)c1c(CNC(=O)c2ccc(Cl)nc2)c(=O)c2ccc(F)cc2n1-c1ccccc1 +CN1CCc2cc(Cl)c(O)cc2C(c2ccc(CN(Cc3ccccc3)c3ccc(F)cc3F)cc2)C1 +Cc1ccncc1CNC(=O)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +C=CC[N+]1(C)CCN(CCNC(=O)n2c(=O)n(C(C)C)c3ccccc32)CC1 +COc1ccc(-c2cn(-c3cc(C(=O)O)ccn3)cc2C#N)cc1 +Cc1cccc(CN2CCCC(C(=O)N3CCc4ccccc4C3)C2)c1 +COc1cc(-c2cc(NC(=O)Nc3ccc(OCCN4CCCC4)cc3)cc(OC)c2OC)ccc1C(C)=O +CNC1CCc2c(c3cc(OC)ccc3n2S(=O)(=O)c2cccc(C(F)(F)F)c2)C1 +Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)cc(-c3cccc(Cl)c3Cl)c12 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)cc2c(=O)n(C)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +CC(=O)Oc1cccc(-c2nc(N3CCOCC3)c3cc4ncccc4n3n2)c1 +Cn1c(Cc2ccccc2)[n+]([O-])c2cc(C=CC(=O)NO)ccc21 +O=S(=O)(c1ccc2c(c1)CCNCC2)N1CCOCC1 +Cc1ccn(-c2ccc(-n3cccn3)cc2)c(=O)c1-c1ccc2nc(N)ncc2c1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NCc1ccc(F)cc1Cl +COCCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(OC(F)(F)F)cc2)c1 +COc1cccc(CN(Cc2cccc(OC)c2)c2ccc3nc[nH]c3c2)c1 +CC1(C)CC2(C)C(=CC1=O)CCC1C3CCC(=O)C3(C)CCC12 +COc1ccccc1N1CCN(CCn2nc(-n3cnc4ccccc43)ccc2=O)CC1 +CC(C)(C)c1ccc(S(=O)(=O)NCCCCCc2c[nH]cn2)cc1 +CNc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2cc(NC(=O)OC)ccc12 +Cc1ncnc(C)c1C(=O)N1CC2CN(CCC3(c4ccccc4)CN(C(=O)C(C)(C)CO)C3)CC2C1 +O=C(Nc1ccc(Cl)c([N+](=O)[O-])c1)c1ccc2ccccc2c1O +COc1ccccc1-n1nc(C2CCN(S(C)(=O)=O)CC2)cc1-c1ccc(Cl)cc1 +CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3CCCOC)CC1 +CNCCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc([N+](=O)[O-])c1 +OCC1CC(O)CN1CCCc1ccc(Nc2nc(-c3cccc(C(F)(F)F)c3)cs2)cc1 +Cc1nc(-c2ccccc2)c(C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)o1 +CCc1cc2c(cc1-c1cnn(C)c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CN(C(=O)Cc1cccc2occc12)C1CCCCC1N1CCCC1 +COc1ccc(Nc2ncc(N3CCC(CO)C3)cc2-c2nc(C)nc3[nH]cnc23)cn1 +Cc1c(-c2c(F)cc(C(N)=O)c3[nH]c4cc(CCO)ccc4c23)cccc1-n1c(=O)cc2c(F)cccn2c1=O +COC1CCC(C(=O)N2CC=C(c3ccc(NC(=O)N4Cc5ccncc5C4)cc3)CC2)CC1 +CC(=O)NCCCOc1ccc(-c2cc(C)cc(Nc3nccc(C(F)(F)F)n3)c2)cc1C(=O)O +Cc1ccc(Oc2ccc(-c3nc4cc(C(N)=O)ccc4[nH]3)cc2)c(Cl)c1 +COC(=O)C1CCC(CN2CCCC2)N(C(=O)Cc2ccc(Cl)c(Cl)c2)C1 +CC(=O)c1cc(NC(=O)NCCCC2CC(Cc3ccc(F)cc3)CCN2)cc(C(C)=O)c1 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+CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(C)=O)cc4)cc3)[nH]c2n(CCC)c1=O +Nc1ccccc1NC(=O)c1ccc(-c2ncc(CN3CCC3)cc2Cl)cc1 +Cc1cc(-c2cnn3c2C(=O)N(c2ccc(C(F)(F)F)cc2)CC3C)ccn1 +O=S(=O)(Nc1ncns1)c1ccc2c(c1)OCCN2c1cccc(OC(F)(F)F)c1 +CCC(C)N(CC(O)c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc(CNC(=O)C(C)(C)C)cc1 +CSc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 +Cc1ccccc1Nc1nc(N)nc(COC(=O)c2ccc([N+](=O)[O-])o2)n1 +CN(C1CCN(CCOc2ccccc2-c2ccccc2)CC1)S(=O)(=O)c1ccccc1 +COc1ccc2cc1Oc1ccc(cc1)CC1NCCc3cc(OC)c4c(c31)Oc1cc3c(cc1O4)CCN(C)C3C2 +COCCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2noc(C)n2)cc1 +O=C(N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)n1cncn1 +CCCCN(C)S(=O)(=O)c1ccc(C(=O)N(CCN(C)C)c2nc3ccc(C)cc3s2)cc1 +COCc1cccc(-c2cc(CCNC(C)=O)c3cc(OC)ccc3c2)c1 +Cc1c(C(=O)O)c(-c2ccc([N+](=O)[O-])cc2)c(C)n1Cc1ccccc1 +N#Cc1cccc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3F)C2)c1 +Cc1nc(N)nc(-c2c(Nc3cc[nH]n3)nc3ccc(-c4ccccc4C)cn23)n1 +CC(Cc1ccc2c(c1)OC(C(=O)O)(C(=O)O)O2)NCC(O)c1cccc(Cl)c1 +NS(=O)(=O)c1ccc(NS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c(Cl)c1 +O=C(CC(Nc1cccc2ccccc12)C(=O)N1CCC(N2CCCCC2)CC1)N1CCC(N2Cc3ccccc3NC2=O)CC1 +Oc1ccc2c(-c3ccccc3)c3cc4ccccc4cc3nc2c1 +S=C(N1CCCc2ccccc21)N1N=C(c2ccccc2)CC1c1ccccc1 +O=c1ccc2nc(-c3ccccc3)nn(-c3ccccc3)c-2c1 +CN(C)C(=O)c1ccc(-c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)cc1 +CC=CC(=O)N1CC2(CC(n3nc(-c4ccc(Oc5ccccc5)cn4)c4c(N)ncnc43)C2)C1 +O=C(CC12CC3CC(CC(C3)C1)C2)NC1CCCC(OCCCN2CCOCC2)C1 +O=C(c1ccc(-c2ccccc2)c(F)c1)C1CCCN(CCO)C1 +CC(Nc1ncnc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +Cc1cc(-c2cnc(C(C)Nc3nccc(N4C(=O)OCC4C(C)F)n3)nc2)ccc1F +CCCCCC=CCC=CCOc1cccc(C(SCCC(=O)O)SCCC(=O)O)c1 +CCC(O)C(CC)Nc1nc(NCc2ccccn2)c2ncn(C(C)C)c2n1 +CCOC(=O)N1CCN([N+]([O-])=NOc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])CC1 +CN(CCCN(C)Cc1ccc(Cl)c(Cl)c1)CCN1CCCC1 +CN1CCN(c2ccc(-c3cc4ncn(C)c(=O)c4c(N4CC(O)C(CO)C4)n3)cc2)CC1 +COCCN(C)c1ncc2ncnc(Nc3cc(C(=O)Nc4ccc(OC)c(C(F)(F)F)c4)ccc3OC)c2n1 +CCC(=O)NC1Cc2c(OC)cccc2C(c2ccccc2)C1 +O=S(=O)(NCCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1)c1ccc2ccccc2c1 +O=C(O)C(Cc1ccc(F)c(F)c1)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +COc1cc2c3c(c4ccc(NS(=O)(=O)C(C)C)cc4c2cc1OC)CN1CCCCC1C3 +CN1C(=O)C(c2ccc(OC(F)F)cc2)(c2cccc(C=CCCCO)c2)N=C1N +Cc1ccc2[nH]nc(C)c2c1-c1nc2c(c(N3CCC(N(C)C)C3)n1)CN(c1c(Cl)c(C3CC3)nn1C)CC2 +Oc1ccc2c3c1OC1c4nc5ccccc5cc4CC4(O)C(C2)N(CC(F)(F)F)CCC314 +CCN(Cc1cccc(OCc2noc(-c3ccccc3F)n2)c1)C1CCN(C2CC(C)C(C)C2)C1 +O=C(NC1CNC1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=c1[nH]c(C2CNC2)nc2c1oc1ccc(Br)cc12 +Clc1ccc(-c2ccc(C3=NOC(c4cccc(-c5cncnc5)c4)N3c3ccc(N4CCNCC4)cc3)o2)cc1 +[H]C([H])([H])N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 +CCn1c(=O)c2nc(-c3ccc(OCOC(=O)C(C)C)cc3)[nH]c2n(CC)c1=O +CCC1(CC#N)CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +Cn1cc(S(=O)(=O)Nc2ccc(F)c(Nc3ncccc3-c3ncnc4[nH]cnc34)c2F)cn1 +CCN(CC)c1ccc2c(C(F)(F)F)cc(=O)[nH]c2c1 +COc1cc2c(cc1O)CC1c3c(ccc(O)c3O2)CCN1C +CN(C)CCN(C)c1cccc(-c2cc(-c3ccc(F)cc3O)nc(NC(=O)c3ccco3)c2C#N)c1 +C=CC(=O)Nc1cccc(-c2cn3nc(-c4ccc(Oc5ccccc5)cc4)c(C(N)=O)c3[nH]2)c1 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+CCc1nc2ccn(CC(=O)N3CCCCC3)c(=O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(C(=O)C(CCC2CCN(Cc3ccccc3)CC2)C(C)=O)cc1 +CCc1ccc(OCCNC(C)Cc2cc3c(c(C(N)=O)c2)N(CCCO)CC3)c(OC)c1 +Nc1nc(NCCNc2ncc(-c3ncc[nH]3)c(-c3cc(F)c(F)cc3F)n2)ccc1[N+](=O)[O-] +COc1cccc(NC(=O)c2ccc(NC(C)C)c([N+](=O)[O-])c2)c1 +CC(=O)NC(CCCCN)C(=O)N1CCCC(C(=O)NCCC(=O)O)C1 +c1ccc(-n2ccc(-c3nnc4n3CCCCC4)c2)cc1 +CCN1C(=O)N(c2ncc(C#Cc3ccc(F)cc3)cn2)CC1(C)C +COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)cc1 +COc1cccc(S(=O)(=O)N2CCN(C(=O)CN(C)c3ccc(Cl)c(Cl)c3)C(CN3CCCC3)C2)c1 +CN(C)CCC(=O)Nc1ccc2nc3c4[nH]c5ccccc5c4ccn3c(=O)c2c1 +Cn1ccc2ccc3c4[nH]c5c(CCN6CCSCC6)cccc5c4c4c(c3c21)C(=O)NC4=O +CN(C)c1ccc(-c2ccc(-c3ccc(O)cc3)s2)cc1 +Fc1ccc2c(c1)-c1ccnc3[nH]c(C4=CCNCC4)c(c13)CO2 +Cc1nn(C)c2ccc(N3CCN(C(=O)C4CCCCC4C(=O)NC4(C#N)CC4)C(C)C3)cc12 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccc4ncccc4c3)cc21 +CCCc1cc(Oc2ccc(S(C)(=O)=O)cc2)ccc1OCCCOc1ccc2c(c1)OC(CC)(C(=O)O)CC2 +CC(C)(C)OC(=O)N1CCc2c([nH]c3cccc4c(=O)[nH]nc2c34)C1 +O=C(Nc1ccc(F)cc1F)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)c1ccccn1 +O=C1C(O)c2cc(Cl)ccc2N1CCn1cc(COc2ccc(CNNc3ccnc4cc(Cl)ccc34)cc2)nn1 +Cc1cc(C(F)(F)F)c(N)c(=O)n1CC(=O)NCc1cc(Cl)ccc1OCC(=O)NCCCN(C)C +Nc1nccn2c(C3CCC3)nc(-c3cccc(OCc4c(F)cccc4Cl)c3)c12 +COC(=O)c1c(NC2CCN(Cc3ccc4c(c3)OCO4)CC2)c2cc(Cl)ccc2n(C)c1=O +O=C1c2ccc(OCC3CCCO3)cc2CCN1C1Cc2ccc(CNC3CCCCC3)cc2C1 +COc1ccccc1CNC(=O)c1cc(C2CC2)nc2c1cnn2C(C)C +CCN1CCN(c2ccc3c(Nc4cc(CCc5c(Cl)c(OC)cc(OC)c5Cl)[nH]n4)ncnc3c2)CC1 +COc1cc(Sc2c(-c3cc4ccccc4o3)[nH]c3ccccc23)cc(OC)c1OC +O=C(O)c1cc(S(=O)(=O)Nc2ccccc2C(=O)O)ccc1O +O=c1c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc2n1NCc1nccs1 +CCCCCCCCN1NCN(c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)C1=O +O=c1[nH]c2cc(Nc3ccc(F)cc3F)ccc2n1CC1CCCCC1 +N=C(N)c1ccc(CN2CCN(Cc3nc4cc(Cl)ccc4[nH]3)CC2=O)cc1 +CC(=O)NC(Cc1ccccc1)C(O)CNC1CC2(CCC2)Oc2ncccc21 +COc1cc(CNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)cc(OC)c1 +CC(C)c1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cc1 +CN1CCN(c2ccc(Nc3nc4c(CCc5ccccc5N(C)S(C)(=O)=O)cccn4n3)cc2)CC1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCC(F)(F)CO2)C(=O)C1CCN(Cc2ccccc2)C1 +COc1cccc2[nH]c3c(c12)CC1c2cc4c(cc2CCN1C3)OCO4 +Fc1cc(F)c2[nH]cc(Cc3c[nH]c4c(F)cc(F)cc34)c2c1 +CCCN(CCCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12)CCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12 +N#CC(=Cc1ccc2[nH]ccc2c1)c1nc2ccccc2[nH]1 +Cn1c(=O)c(S(=O)(=O)c2ccc(O)cc2)cc2cnc(Nc3ccc4[nH]ccc4c3)nc21 +NC(=O)c1cccc2c1C(=O)N(c1ccc(CN3CCCC3)cc1)C2 +COc1cccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)c1 +CN1C(=O)C(NC(=O)CCCCCCC(=O)NO)N=C(c2ccccc2)c2ccccc21 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c(-c2ccncc2)nn1CC(=O)O +NC(=O)c1ccc(OC(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c2ccccc12 +COC1CCC(Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1 +Cn1c2ccccc2c2[nH]cc3nc4ccccc4c-3c21 +CC1(C)C2CC(CC=CCCCC(=O)O)C(NC(=O)c3csc4c3CCCC4)C1C2 +Cc1cc(-c2nc(-c3ccc(Cl)c(C(F)F)c3)n3c2CCOCC3)ccn1 +Cc1c(NS(=O)(=O)c2ccc(-c3cccc(C(C)(C)N)c3)cc2)c(CC(C)C)nn1C +NCc1ccc(-c2ccc3ncc(-c4ccncc4)n3n2)cc1 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+O=C(NCC(F)(F)F)C1(CCCCP(=O)(OCCCc2ccccn2)OCCCc2ccccn2)c2ccccc2-c2ccccc21 +COc1ccc2nc(-c3ccc(Cl)cc3)n(C(C(=O)NC3CCCCC3)C3CCCCC3)c2c1 +NC(=O)c1cnc2cc(-c3ccncc3)ccc2c1Nc1ccc(F)cc1 +CC1COc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc2N1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(Cl)c(Cl)c3)CC2)nc1 +COC(=O)c1sc2ncnc(Nc3cccnc3OC(C)C)c2c1C +O=C(NCCCCl)NCC1OC(n2cc(Cc3ccc(C4CC4)cc3)c3c(Cl)cccc32)C(O)C(O)C1O +CCC(NC(=O)c1c(Br)c(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 +CC(C)(C)c1cnc(CSc2cnc(NC(=O)Cc3ccc(OCCCCC(=O)NO)cc3)s2)o1 +CC1=CC23C(=O)C(C=C(CO)C(O)C2(O)C1OC(=O)c1c(N)cccc1Cl)C1C(CC3C)C1(C)C +Cc1ccccc1-n1c(Cn2nc(C#CC(C)O)c3c(N)ncnc32)cc2cccc(C)c2c1=O +CN(C(=O)CN(CC(=O)NCCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 +COC(=O)C1C2CC3CCC1N3CC2=CC#Cc1cc(F)ccc1F +COC1CCC2(CC1)Cc1cc(F)c(-c3cccc(C#N)c3)cc1C21N=C(N)N(C)C1=O +O=Cc1c(OCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)nn2ccccc12 +CCS(=O)(=O)N1CCN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)CC1 +COc1ccc(O)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 +CCC(C)C(N)C(=O)N1CCC1C(=O)c1nc2ccccc2s1 +CC(C)Oc1ccccc1OCCN1CCC(NS(=O)(=O)c2cc(Cl)ccc2F)C1 +CC(C)(C)NS(=O)(=O)c1cncc(-c2ccc3nc(NC(=O)NCCc4ccccc4)nn3c2)c1 +COc1ccc(Nc2ncc(Cl)c(Nc3cccnc3C(N)=O)n2)cc1N1CCN(C)CC1 +Cc1cncn1CCCN=C(C[N+](=O)[O-])Nc1ccc2c(c1)OCCO2 +O=C(NCC(c1ccccc1)c1ccnnc1)c1ccc(Cl)cc1Cl +CCNC(=O)Nc1nc2ccc(-c3ccnc(C)c3)cc2[nH]1 +CC1(C)Oc2ncnc(N)c2C=C1c1ccc(C2CCC(CC(=O)O)CC2)cc1 +COCc1nc(CN(C(=O)CCC(C2CCCCC2)N2Cc3cc(Oc4ccccc4)ccc3N=C2N)C2CCCCC2)cs1 +CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1cc(Cl)c(C(=O)O)cc1Cl +CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3CNc3ccccc3)cc2)cc1 +CCCCS(=O)(=O)N1CC2CCC1C(C(=O)Nc1ccc(Cc3ccccc3)cc1)C2 +COCC1CCC(C)C(O)(C(=O)C(=O)N2CCCCC2C(=O)OCc2ccccc2)C1 +C=C(C)Cn1c(SCC(=O)c2cccs2)nc2sc3c(c2c1=O)CCCC3 +CC(C)C(C)NC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=C(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)C1(O)CCCCC1 +CCOC(=O)c1c(-c2nc(CCO)no2)c(CCO)n2nc(N3CCOCC3)cc(-c3ccccc3)c12 +COc1ccc(C(=O)N(C)C2(c3ccccc3)CCC(c3ccccc3)(N(C)C)CC2)cc1 +CC(C(O)c1ccc(O)cc1)N1CCC(O)(Cc2ccccc2)CC1 +O=S(=O)(c1ccccc1)c1cc2c(N3CCNCC3)cccc2[nH]1 +COc1ccc(N=c2oc3cc(O)ccc3cc2C(=O)Nc2ccccn2)cc1 +OC(CNC(Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)CC(F)(F)F +CCOC(=O)c1ccc2c(c1)C1C=CCC1C(C(=O)O)N2 +CC12CCC(O)CC1=CCC1C2CCC2(C)C(c3n[nH]cc3C#N)=CCC12 +Cc1nc(N2CCC(NC(c3cccnc3)c3ccc(Cl)cc3F)CC2)no1 +COc1ccc(C(=O)c2csc(S(N)(=O)=O)c2)cc1 +CC1(C)CC=C(c2cc(Cc3nnn[nH]3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +CNc1nc(C2c3cc(F)ccc3CN2C(=O)C(O)C(O)C(=O)NC(C)c2ccc(-n3cccn3)cc2)cs1 +CNC(=O)C1CCC(Nc2cc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 +Oc1ccc(N2CCN(Cc3cnn(-c4ccc(Cl)cc4)c3)CC2)cc1 +O=C(Nc1cccc(-c2ccnc3c(-c4ccc(CN5CCCC5)cc4)cnn23)c1)c1cccc(C(F)(F)F)c1 +O=C(NCC1CCO1)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CC(Nc1ncnc(N)c1C#N)c1nn2c(C(F)(F)F)ccc2c(=O)n1-c1ccccc1 +O=C(CCCN1CCN(c2ccc(F)cc2)CC1)NC1c2cc(F)ccc2SCC2CCCCC21 +Cc1cc(-c2ccc(NCc3ccc(Cl)cc3-c3ccc(C(=O)NCCC(=O)O)nc3)cc2)ccc1F +Cc1nn(Cc2ccc3c(c2)OCO3)c(=O)c2nc(C)n3nc(-c4ccccc4)cc3c12 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3nccc4[nH]ccc34)c2)c2cncnc21 +CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1)c1ncccc12 +Cc1ccc(C(=O)NC(C)(C)CO)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CCCCn1c(=O)c(C(=O)NC2CCC(C)CC2)c(O)c2cccnc21 +Cc1cc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)OCC3F)c2)nn1C +O=C(NCCCCc1cccnc1)c1ccc2nc3cc(Cl)ccc3c(=O)n2c1 +CCc1ncnc(-c2ccc(C(=O)N3CCc4ncccc4C3)c(F)c2)c1C#Cc1ccc(N)nc1 +CC1(C)CC2CC(C)(CN2C(=O)c2ccc(-c3ccc(-c4cccc5cccnc45)cc3Cl)cc2Cl)C1 +CCS(=O)(=O)Nc1cccc(N(Cc2ccccc2)Cc2ccccc2)c1C +COc1c(OCCN2CCCCC2)cc(F)c2c(-c3ccc(O)c(Cl)c3)nc3[nH]nc(C)c3c12 +CCCCCCCC(=O)CCCCCCC=CC(C(=O)NC(Cc1cccs1)C(=O)O)C(O)(CC(=O)O)C(=O)O +OCc1nccc(N2CCN(c3ccc4ccccc4n3)CC2)n1 +O=C(NC1CCN(Cc2ccccc2)C1)c1cccc(-c2ccsc2)c1 +O=C(NCC1(CC2CC2)C2CN(S(=O)(=O)CC3CC3)CC21)c1ccc(Cl)cc1Cl +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4COc5ccccc5C4)ncc23)ccn1 +Cc1cccc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)n1 +Clc1cccc(-c2ncccc2CC(c2cccnc2)c2cccnc2)c1 +c1ccc(-c2nc(NC3CCCCC3)cc(C3CC3)n2)nc1 +COc1cc(CNc2nc(-c3cccc(C)n3)c(-c3ccc4ncnn4c3)s2)cc(OC)c1 +Cc1oc(-c2ccccc2)nc1CCNc1ccc(CC(C(=O)O)n2cccc2)cc1 +CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCC(=O)OC(C)(C)C)CC1 +Oc1ccc(-c2cc(-c3ccccc3)c(-c3ccc(O)cc3F)s2)c(F)c1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc4cnccc4n3)n[nH]c2C1(C)C +Cn1cc(-c2ccc(-c3cncc4ccc(N5CCOC5=O)cc34)cc2)cn1 +COc1cc2nc(-c3ccccn3)n(-c3ccc4c(N)nc(N)nc4c3)c2cc1OC +Cc1ccc(Sc2cccc3[nH]c4nc(N)nc(N)c4c23)cc1 +CCCN(C)C(=O)OC1=C(c2ccccc2)Oc2ccccc2-n2cccc21 +CCCC(CC1(C(=O)NC2CC2c2ccccc2)CCCC1)C(=O)O +O=C(C=Cc1ccc(CNc2nccc(-c3cccnc3)n2)cc1)NO +COc1c(C)cc(-c2ccccc2)cc1C(=O)NC1CCCCCC1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OC(C)CN(C)C)c(C(=O)O)c2)c1 +CC(Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1C(F)F +COc1cc2ncnc(Oc3ccc(NC(=O)NC4CC4)c4ccccc34)c2cc1OC +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1(S(=O)(=O)c2ccccc2Br)CCCCC1 +O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccc(Cl)cc12 +CC1CC(=O)NN=C1c1ccc2c(c1)CCC(=O)N2C +CCn1c2ccccc2c2cc(NC(=O)N3CCOCC3)ccc21 +O=C1C=CC2(C=C1)OCC(c1cccc(-c3ccc(F)cc3)c1)O2 +Fc1ccc(NC(=S)Nc2cccc(C(F)(F)F)c2)cc1Cl +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(N3CCCC3=O)cc2n1Cc1ccccc1 +O=C1NC(=S)N(C2CCCCC2)C(=O)C1=CNNC(=O)c1ccccc1 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-n3cccn3)ccnc12 +O=c1ccn(CCCS(=O)(=O)N2CCCC2C(O)(c2cccc(F)c2)c2cccc(F)c2)c(=O)[nH]1 +COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc([N+](=O)[O-])ccc1Cl +O=C(NCC1(O)CC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CCN(CC)CCCNC(=O)C1CN(S(=O)(=O)c2ccc(OC)c3ccccc23)c2ccccc21 +O=C(NO)C1CCC(O)CN1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(Cl)cc1-c1cc(N2CCC2)ncn1 +O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCN3CCCCC3)c2=O)cc1 +COc1cccc(CCCCCCC(=O)c2ncc(-c3ccccn3)o2)c1 +CCCn1c(=O)c2nc(-c3ccco3)[nH]c2n(CCC)c1=S +Cc1ccc(NC(=O)Nc2ccc3c(-c4cnco4)c[nH]c3c2)cc1 +OC1CC(OCc2ccc(F)cc2)CCC1N1CCc2ccccc2C1 +Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1nc2cc(N(C)CCO)ncc2[nH]1 +CC1CCN(C(=O)C(CCn2cccc2C#N)NS(=O)(=O)c2ccc3cc[nH]c3c2)CC1 +COc1cc2c(cc1OC)C(=O)N1C=C(c3ccc4ncccc4c3)CC1C(S(=O)(=O)O)N2 +COc1ccc2ccc(OC3CCN(c4ncnc5cc(OC)c(OC)cc45)C3)cc2c1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CC(CC(=O)c1ccccc1)C(=O)NC1c2ccccc2CC1O +CC(Cc1c[nH]c2c(OC(C)C)cccc12)NCC(O)c1cccc(NS(=O)(=O)c2cccs2)c1 +COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccccc2F)cc1 +CC(NC(=O)c1cc(-c2nc3cc(F)ccc3[nH]2)cc(N(C)S(C)(=O)=O)c1)c1ccccc1 +Cc1oc(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)Nc2ccccc2F)nc1C(=O)O +N#Cc1ccc(Cn2cncc2COCc2ccc(C#N)cc2-c2ccc3c(c2)OCO3)cc1 +CC(C)(N)C(=O)N1CCC(CCn2c(Sc3cc4c(cc3Br)OCO4)nc3c(N)ncnc32)CC1 +Cc1cc2c(c(Oc3cccc(NS(=O)(=O)c4ccc(Cl)cc4)c3)n1)C(=O)NC2=O +Cc1nc(N)ccc1CNC(=O)C1C=CCn2c(=O)n(C(CSc3ccc(Br)cc3)C(=O)OC(C)C)c(=O)n21 +CN1CCC(Oc2ccc(-c3n[nH]c4ccc(C(=O)NC(c5ccccc5)C5CC5)cc34)cc2)CC1 +CN1CCN(CCN(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)C2CCC3(c4cccc(C#N)c4)CC23)CC1 +COc1ccc(CCCO)c(Nc2nc3ccccc3nc2NS(=O)(=O)C2CCNCC2)c1 +[C-]#[N+]c1ccc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CO2)cc1F +O=C(Cc1cccc2ccccc12)NCCCCCC(=O)N1CCC(CNCCCCNCC2CCNCC2)CC1 +CC(C)(C)OCCN1CCC(CNC(=O)c2cc(Cl)cc(Cl)c2)CC1 +CCC(C)n1ccnc1C=CC=CC(=O)C=Cc1ccccn1 +O=C(CCc1ccc2ccccc2c1)Nc1ccccc1C(=O)O +O=S(=O)(c1c(Cl)nc2sccn12)n1ccc2ncccc21 +NC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(C4CC4)n3)CC3CC32)c2ccccc12 +N#CC1(NC(=O)C(CS(=O)(=O)Cc2ccccc2-c2ccccc2)NC(c2ccc(F)cc2)C(F)(F)F)CC1 +CCc1cc(-c2noc(-c3cc(OC4CCCC4)cc(C)n3)n2)cc(C)c1OCC(O)CNC(=O)CO +CNC(=O)Nc1ccc(-c2nc(N3C4CCC3COC4)nc3c2C(=O)N(C)CC(C)(C)O3)cc1 +CCc1nc2c(n1C(C1CC1)C1CC1)C(=O)N(C)CN2c1ccc(Cl)cc1Cl +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1CCCC(=O)NCCO +NC1=NC2(c3ccc(F)cc3F)COC(c3ccn(C4CC4)n3)CC2CS1 +COc1cccc(CNC(=O)c2sc3nc(C)cc(C)c3c2N)c1 +CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCc3ccccc3C2)s1 +Cc1ccc(C(=O)Nc2ccc(OC(CCN(C)C)c3ccccc3)cc2)cc1Cl +CN(C)c1ccc2c(COc3ccc(Cl)c(Oc4cc(Cl)cc(C#N)c4)c3)noc2n1 +Cc1ccc(C=CC(=O)Nc2ccc3nc(N(C)CCN(C)C)cc(C)c3c2)cc1 +CNc1ncc2cc(-c3cc(NC(=O)Nc4cccc(C(F)(F)F)c4)ccc3C)ccc2n1 +CC(C)(C)c1ccc(Oc2ccc(-c3cc(C(=O)O)c4cc(F)ccc4n3)cc2)cc1 +NC1=NC2(c3ccc(F)cc3F)COC(C(F)F)CC2CS1 +CC1CC2=C(C3Oc4c(O)ccc5c4C34CCN(CC3CC3)C(C5)C4(O)C2)N(Cc2ccccc2)C1=O +Cc1c(NC2CCCCC2)cccc1-c1ccc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)nc1C(=O)O +O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1)c1ccccc1Cl +C#CCN(Cc1ccc2nc(C)n(C)c(=O)c2c1)c1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1 +N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)N(CC(=O)O)Cc4ccc(CC(=O)O)cc4)ccc3c2)cc1 +NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3ccc(I)cc32)cc1 +CCC(CC)c1nc2c(-c3ccccc3)cc(-c3ccccc3)nc2[nH]1 +Cc1nsc(-c2nnc3n2CCN(C(=O)c2ccc(F)cc2)C3(C)C)n1 +CNC1CCN(c2nc(N)nc3c2Cc2ccccc2-3)C1 +Cc1ccc2c(O)c3c(c(O)c2n1)C(=O)N(Cc1cccc(Br)c1)C3=O +O=C1OC2(CCC(c3nc4cc(OC(F)(F)F)ccc4[nH]3)CC2)CN1c1ccc(F)cc1 +COc1ccc(C#CCN(c2cc(OC)cc(OC)c2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)nc1 +O=C(COc1ccccc1)NC(c1ccccc1)c1cc(Cl)c2cccnc2c1O +CCc1nc(C)c2c(NC(C)=O)nc3ccc(OC)nc3n12 +Cc1cc(N2CCCCC2)nc(NCCCNc2ccnc3cc(Cl)ccc23)n1 +COCCOc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +CCCCN(C)C(=O)C(CC1CCCCC1)NC(=O)C(CC(C)C)NC(=O)Cc1ccc(F)cc1 +N#CC1(NC(=O)C2CCCCC2C(=O)N2CCc3[nH]c4c(F)cccc4c3C2)CC1 +O=C(O)CCC(CP(=O)(O)CC(Cc1ccccc1)C(=O)O)C(=O)O +CCCc1c(OCc2ccc(C(=O)O)cc2F)ccc(C(C)=O)c1O +CCS(=O)(=O)c1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)c3cncn23)c1 +O=C(c1cncs1)c1nc(NCc2cccnc2)nc2ccsc12 +CC(C)CN(NC(=O)c1ccccc1Oc1ccccc1)c1nc(C#N)ncc1Br +COc1ccc(C=CC(=O)OCC(=O)NCc2ccco2)cc1OC +O=C(O)C1CCCN(CCC=C(c2ccccc2F)c2ccccc2F)C1 +O=C(CN(c1ccc(Cl)cc1)S(=O)(=O)c1ccccc1)NN=C1C(=O)Nc2ccccc21 +Cc1cccc(-c2nc(Nc3ccc4ncsc4c3)c3ccccc3n2)n1 +CCCn1c2ccccc2c2cc(C(=O)N3CCCCC3)ccc21 +CCOC(=O)c1c(C)[nH]c(C(=O)NN=Cc2cc([N+](=O)[O-])ccc2O)c1C +CC1CCN(C2CC(Oc3ccc(Cl)cc3)c3c(c4ccccc4n3CC3CCNCC3)C2=O)CC1 +O=C(O)CCc1ccc(OCc2ccccc2-c2ccc(Br)cc2)cc1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(-c2ccncc2)nc1OCC#CCO +COc1cccc(Nc2cc(C)nc3ccc(NC(=O)Nc4ccc(N(CCCl)CCCl)cc4)cc23)c1 +Nc1ccc(N2C(=O)N(c3ccc(N)c(F)c3)C(Cc3ccccc3)C(O)C2CCc2ccccc2)cc1F +N#Cc1ccc2[nH]cc(C3CCC(N4CCOCC4)C3)c2c1 +CCCCc1nc2cccc(COC)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COCC1CCN(c2nc(NCCN3CCCC3)nc3scc(-c4ccccc4)c23)CC1 +CN(C)C(=O)c1ccc2c(c1)OCC(N1CCc3c(nn(Cc4ccccc4)c3Cl)C1=O)C(=O)N2C +CCOC(=O)CNP(=O)(COc1cc(C)c(C)c2c1-c1ncsc1C2)NCC(=O)OCC +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(I)cc12 +CC1CCC(Oc2ncccc2C(C)(C)O)CN1C(=O)c1ccsc1-n1nccn1 +Nc1nonc1-c1nc2cncc(C(=O)N3CCC(N)C3)c2n1CC1CC1 +Cn1cc(-c2cccc(-c3ncc(-c4cnn(C5CCCN(S(C)(=O)=O)C5)c4)cn3)c2)cn1 +C=CC(=O)Nc1cccc(CNc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2C(F)(F)F)c1 +CC(C)CCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 +Cc1cc(C)n(-c2cc(NC(=O)CCN(C)C)nc(-c3ccc(C)o3)n2)n1 +COC12CCC3(CC1COc1ccc(-n4ccnc4)cc1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4cccc(Cl)c4)c23)c1 +O=C(O)Cc1cc(Cl)c(Oc2ccc(O)c(-c3cccc(-c4ccccc4)c3)c2)c(Cl)c1 +CS(=O)(=O)N1CCN(c2ccnc(-n3ccnc3)n2)C(CC(=O)NCc2ccc3c(c2)OCO3)C1 +N#Cc1ccc(-c2n[nH]c3c2Cc2ccc(OCCCCN4CCOCC4)cc2-3)cn1 +CC(=O)c1cncc(-c2cccc(C(C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)c1 +CSCCC(NC(=O)c1ccc(CN(c2cccnc2)S(=O)(=O)c2ccccc2)cc1-c1ccccc1C)C(=O)O +Cc1cc2c(cc1Cl)N(C(=O)Nc1cnc(Oc3cccnc3C)c(Cl)c1)CC2 +COc1ccnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +COc1ccc(NC(=N)c2ccsc2)cc1CSC1CCCC1 +COc1ccc2nccc(NCCCCCCCNc3ccnc4ccc(OC)cc34)c2c1 +CN(C)c1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1 +N#CC1CN(C(=O)OCCC2CC2)CCC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +CC(C)N1C2CCC1CC(c1cc(-c3ccc(F)cc3Cl)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c1)C2 +CC(C)Oc1ccc(Cc2ccccc2)cc1C(=O)CC(=O)C(=O)O +Cc1cc(S(=O)(=O)n2cc(NC(=O)c3ccccn3)cn2)ccc1Cl +CC1=C(C(=O)OCc2ccc3c(c2)OCO3)C(c2ccoc2)NC(=O)N1 +COc1ccc(-c2cc3c(NC4CCC(C)(N)C4(C)C)c(C(N)=O)cnn3c2)cn1 +Cn1c(COc2ccc(C(C)(CCC(=O)O)c3ccc(OCc4ccc5ccccc5n4)cc3)cc2)nc2ccccc21 +COc1ccc(C2C(Oc3ccccc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1N +Nc1nnc(-c2ccc3[nH]cc(-c4cccc(OC5CCC5)n4)c3c2)s1 +COCCOc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 +Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(C(=O)N(C)C)cc4)c3Cl)cccn2c1Br +O=C(O)c1cncc(Oc2cnc(NC(=O)C(OC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)c1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)cc2[nH]c(=O)oc12 +CC(Oc1ccc2ccccc2c1)C(=O)NNC(=S)NC(=O)c1ccco1 +COc1cc(C(=O)N2CCOCC2Cc2cccc(-n3nccn3)c2)c(-n2nccn2)cc1C +CNC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)C4CC4)ccc3C)cc1CC2 +COc1ccc2c(c1)OCC(N1CCC(O)(c3ccc(F)cc3)CC1)C2O +CCCCC(CN(O)C=O)C(=O)NC(C(=O)c1ccc(N)cc1)C(C)(C)C +O=C(O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CS)c1cccc(-c2ccccc2)c1 +CC1CN(CCc2ccncc2)CCN1S(=O)(=O)c1ccc(C(C)(O)C(F)(F)F)cc1 +CC(C(=O)NCC(F)F)c1ccc(OC2CCN(c3nc(N(C)C)ncc3F)C2)cc1 +CN(C)CCCOc1ccc2c(=O)cc(-c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)oc2c1 +COc1ccc(CN2C(=O)C(=O)c3cc(C=CC(=O)N4CCCC4)ccc32)cc1 +COc1ncc(Nc2ncc(CN3CCOCC3)cc2-c2nc(C)nc(N)n2)cc1NS(C)(=O)=O +CCCCC(C)OC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +O=C(Cc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Cl)cnc32)CC1 +CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OC)cc(C)nc34)c2Cl)cc1 +CN(Cc1cccc(B(O)O)c1)c1ccc(C(=O)Nc2ccc(F)cc2)cn1 +Cc1ccc(OCc2ccc3c(c2)CCN(C2COC2)C3)c(-c2cccc(N3CCC4(C(=O)O)CC4C3)n2)c1 +CC(Oc1cccc(Cl)c1)C(=O)N(CC1CCCN1)c1ccccc1 +Cn1c(=O)c2nc(-c3ccc(S(=O)(=O)Oc4cccc([N+](=O)[O-])c4)cc3)[nH]c2n(C)c1=O +CC(=O)N1CCC(Cn2c(C(C)(C)C)nc3cc(S(=O)(=O)c4ccncc4)ccc32)CC1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCCCCC2)C1=O)c1ccccc1 +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C1N(Cc2cccc3ccccc23)CCCC12CCN(c1nc3ccccc3[nH]1)CC2 +CCn1nc(-c2cccc(-c3ccccc3C(=O)O)c2)cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O +CCC(N)COc1cncc(-c2cc3c(cnc4cc(OC)c(OC)cc43)c(N)n2)c1 +O=S(=O)(NCCCCN1CCN(c2noc3ccccc23)CC1)c1ccc2cc(Cl)ccc2c1 +Cc1c(N(Cc2cc3cccc(Cl)c3n2C)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +CCc1cc(Nc2cc(=O)n(CCN3CCN(C(=O)c4ccccc4)CC3)c(=O)[nH]2)ccc1C +O=C(c1ccc(F)cc1Cl)N1CCn2c(nnc2-c2cccc(Cl)c2)C1 +COc1cc(N2CCN(CC(C)O)CC2)c(F)cc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc([N+](=O)[O-])o1 +C#CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +C=CCN1CCN(c2nc(NCCc3ccc(O)cc3)nc(N(C)CCCc3ccc(Cl)cc3)n2)CC1 +CCN(CC)c1ccc(C=CC(=O)c2ccc(OC(=O)C(C)C)c3c2OC(C)(C)C=C3)cc1 +CCOc1ccc(-c2nc(C)c(C(=O)O)[se]2)cc1C#N +O=C(c1ccc(O)c(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)c1)N1CCN(c2ccc(Cl)cc2)CC1 +COC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCc1ccccc1 +CS(=O)(=O)c1cccc(C(=O)Nc2nc3ccccc3n2CCCO)c1 +CS(=O)(=O)c1ccc(CC(NC(=O)c2c(Cl)cc3c(c2Cl)CCN(C(=O)c2ccc(Cl)cc2)C3)C(=O)O)o1 +CSc1nnc(NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3-c3ccnn3C)c(C#N)c2)s1 +CC(C)c1ccc2oc(NC(CN3CCOCC3)c3ccccc3)nc2c1 +Cc1cc(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)n(C)n1 +Cn1c(=O)sc2cc(CCN3CCN(c4cccc(C(F)(F)F)c4)CC3)ccc21 +CC(=O)Nc1cccc2c3c4c(cccc4cc12)C(=O)N(CCN(C)C)C3=O +COc1ncccc1NC(=O)N1CC(C)N(c2ccc(C#N)c(C(F)(F)F)c2)CC1C +COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2cccc(F)c2)CC1 +CCCC(=O)Oc1cccc2c1-c1cccc3c1C(C2)N(CCC)CC3 +CC(=O)n1c2cc(=O)n(Cc3cccnc3)c(C)c2c(=O)n1-c1ccccc1 +Cc1cc(NC(=O)c2ccc([N+](=O)[O-])o2)ccc1NC(=O)c1ccco1 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccc(Cl)cc3Cl)CC2)n1 +O=C(NCCCCCCS)c1cc(-c2c[nH]c3ccccc23)n[nH]1 +COC(=O)N(NC(=O)c1c(CN2CCCCC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +CC(C)(O)c1csc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)n1 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCNc3ccc(F)cn3)c2)c1 +O=C(c1ccccc1)N1CCN(c2nnc(-c3ccc(Cl)c(Cl)c3)c3ccccc23)CC1 +COc1ccc(-c2cc3[nH]c(=O)c4ccccc4n3n2)c(OC)c1 +O=C(Nc1ccn(S(=O)(=O)Cc2cccc(F)c2)c1)c1ccccn1 +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)c(Cl)c1 +CN(Cc1cc2c(s1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C)CC(O)c1ccc(O)cc1 +COc1ccccc1Sc1nccc(-c2ccc3nc(NC(C)=O)sc3c2)n1 +COc1ccc2c3c1OC1c4[nH]c5ccccc5c4C(C)C4C(C2)N(C)CCC314 +CN(Cc1ccc(C2=NCCN2)cc1)C(=O)COCCN(C)S(=O)(=O)c1cccc(Cl)c1Cl +COc1ccc(OC)c(-c2cccc(C(CC(=O)O)c3ncc(C)s3)c2)c1OC +CN(C)CCCNC(=O)c1ccc2c(c1)CC(c1nc3ccc(-c4cn[nH]c4)cc3s1)CO2 +CN1CCN(CCS(=O)(=O)Nc2ccc(C=C3Oc4c(C(N)=O)cccc4C3=O)cc2)CC1 +COc1cc(-c2cc(NC(C)c3cccc(OCc4ccn(C)n4)c3)nc(C)n2)ccc1C +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(-c3ccc(CO)s3)c2c1=O +CC(=O)Nc1cccc(C2CCN(CCCn3c(-c4ccc(Oc5ccccc5)cc4)nc4ccccc43)CC2)c1 +O=C(Nc1cc(-c2ccc(Br)cc2)[nH]n1)c1cccnc1F +CCC(NC(=O)c1c(N)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +COc1ccc(CNC(=O)c2ccc(Oc3ccc(C#CC4(O)CN5CCC4CC5)cc3)cc2)cc1OC +CCC1(OC(=O)N2CCN(c3ncc(OCc4ccncc4C#N)cn3)C(C)C2)COC1 +O=C(c1c(F)cccc1-n1nccn1)N1CCC2CN(c3cnc4ccccc4n3)C2C1 +Cc1ccc(NC(=O)COc2ccc(-c3nc4c(=O)n(C)c(=O)n(C)c4[nH]3)cc2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccccc1F)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1cccc(C)c1Nc1nn(CCCN(C)C)c2nc(Nc3ccccc3)ncc12 +CCCCc1ncc(C(=O)OC)n1Cc1ccc(-c2ccccc2NS(=O)(=O)NC(=O)C2CC2)cc1 +CCCCN(CCCC)C(=O)c1nc(-c2ccccc2)no1 +CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 +CCOc1cccc(-c2cc(F)ccc2C2Cc3nc(N)nc(C)c3C(=O)N2)n1 +O=C(Nc1ccc(F)cc1)c1c(NO)cc(-c2cccs2)oc1=O +CN(C)C(=O)c1cc(N2CCN(C(=O)n3nnc4ccccc43)CC2)ccc1[N+](=O)[O-] +CC(C)NC(=O)Nc1nc2nc(NCCCN3CCN(C)CC3)ncc2cc1-c1c(Cl)cccc1Cl +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NCC(=O)O)cc2C)ncn1 +CCC(C)C(NC(=O)C(CC(O)C(CC1CCCCC1)NC(C)=O)C(C)C)C(=O)NCc1ccccn1 +COc1cncc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)n1 +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1ccccc1Nc1ccccc1 +N#Cc1ccc(Nc2cc(Oc3c(Cl)cc(Cl)cc3Cl)c([N+](=O)[O-])cn2)cc1 +CC(C)CN(NC(=O)c1ccc(-c2ccccc2)s1)c1nc(C#N)ncc1Br +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CC[S+]([O-])CC4)ncn3)c2c1 +O=C(NC1CCN(CC2CCCC2)CC1)C(O)(c1ccccc1)C1CCCC1 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3cccc(Cl)c3)cc12 +CN1CCC(CS(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CC2CC2)CC1 +Cc1c(-c2ccc(CC(NC(=O)c3c(F)cccc3F)C(=O)O)cc2)c(=O)n(C)c(=O)n1C +Brc1cnc2nc(-c3ccc(C4CNCCO4)cc3)[nH]c2c1 +CCOc1ccc(-c2cc(Cl)cc3c2N2CCNCCC2C3)cc1 +Cc1cc(OCc2nc(-c3cncnc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)NCC3(O)CNC3)cc2F)cn1 +CCC1=C(CC)CC2=C(C1)CC(NCC(O)c1ccc(O)c3[nH]c(=O)ccc13)C2 +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1ccccc1I +Cc1ccn(-c2ccc(C(=O)N3Cc4cccnc4N(C)c4ccccc43)c(Cl)c2)n1 +Cc1ccc(-c2nc3c(N)cc(C(=O)N4CCCC4)cn3n2)o1 +CC(Oc1cc(F)ccc1Nc1ncnc2cc(N=S3(=O)CCC3)cc(Cl)c12)C(=O)NCC(F)(F)F +Cc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(C)CC2)c(=O)n4C)cn1 +O=C(NO)C1Cc2c([nH]c3ccccc23)CN1S(=O)(=O)c1ccc(N2CCOCC2)cc1 +COc1ccc(CN2CCC3(CCc4ccccc4C3=O)CC2)cc1 +CCC(C)C1NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)CC(C=Cc2ccccc2)OC(=O)C(C(C)C)NC1=O +c1ccc(CNc2nc(Cc3ccccc3)cc3c2CCNCC3)cc1 +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(OC)cc1)C(=O)C(C)C +O=C(NCC12CCC3(O1)C1Cc4ccc(O)cc4C3(CCN1Cc1ccccc1)C2)c1cccc(O)c1 +CNc1nc(Nc2cc(OC)c(C(=O)N3CCNCC3)cc2Cl)ncc1Cl +COc1ccc(CCC2CCN(CCc3ccccc3OC)CC2)cc1 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)N(C)CC(=O)NC(C(=O)C(F)(F)F)C(C)C +O=C(NC1CNC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)N3CCN(C)CC3)ncc2c1 +Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ncn1 +CCOC(=O)c1cnc2c(c1)CC1(O)C3Cc4ccc(O)c5c4C1(CCN3CC1CC1)C2O5 +CCCCC#CCOC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 +CC(C)c1ccccc1Sc1ccc(-c2cc(N3CCC(c4nn[nH]n4)CC3)ncn2)cc1C(F)(F)F +Cc1cc(C)cc(-c2c(O)nc3cc(Cl)c(C(=O)Nc4cc(C)nc(C)n4)cc3c2OCCC2CCCCN2)c1 +CCOC(=O)c1cc2cc(-c3cc(C(=O)NCc4ccc(CC(=O)OC)cc4)nn3C)ccc2[nH]1 +O=C(NCC(c1ccc(Cl)cc1)C1CCOCC1)c1cccc(Cl)c1Cl +CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2c1 +COc1cccc(C(=O)NN2c3ccc(Cl)cc3N=C(N3CCN(C)CC3)c3cc(Cl)ccc32)c1 +OC12C=C(c3nccc4c3[nH]c3ccccc34)C3CCN(CCCCC=CCC1)CC31CC3C=CCCCCN3C21 +C#Cc1cccc2nc(Cn3nc(-c4cccc(O)c4)c4c(N)ncnc43)n(Cc3ccccc3Cl)c(=O)c12 +CCOC(Cc1ccc(OCCN2CC=C(c3ccccc3C(F)(F)F)CC2)cc1)C(=O)O +COc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 +CN1C2COCC1CC(NC(=O)c1cn(CC(C)(F)F)c3ncccc13)C2 +CSc1nc(N2CCOCC2)c2cnn(CC(Br)c3ccccc3)c2n1 +O=[N+]([O-])c1cccc(NC(P(=O)(O)O)P(=O)(O)O)c1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1ccc(CNC(C)C)cc1 +Cc1ncc(C[n+]2csc(CCOP(C)(=O)OP(=O)(O)O)c2C)c(N)n1 +COc1cnc2ccc(Cc3nnc4ccc(-c5ccccc5)nn34)cc2c1 +COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(OC(F)(F)F)cc4)cc3F)c(=O)c2cc1Cl +CNC(=O)c1cc(-c2ccnc(C)c2C#Cc2ccc(N)nc2)ccc1Cl +CC1c2cc3c(C(F)(F)F)cc(O)nc3cc2NC(C)(C)C1C +CCOC(=O)CC(NC(=O)c1ccc(NCc2ccc3nc(N)nc(N)c3c2C)cc1)C(=O)OCC +CSCCC(NC(=O)c1ccc(COCc2ccc(-c3ccc(C=O)cc3)o2)cc1-c1ccccc1C)C(=O)O +CCCCCNc1ncnc2c1ncn2C1OC(COS(N)(=O)=O)C(O)C1O +CC1CCC2C(C)C(OCCC3ON3C(=O)c3ccccc3O)OC3OC4(C)CCC1C32OO4 +CNC(=O)c1cccc(S(=O)(=O)Nc2ncc(Br)nc2OC)c1-c1ccccc1 +COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 +COc1cc2ncnc(N3CCNC(c4ccc5c(c4)OCO5)C3)c2cc1OC +CCNCC(=O)Nc1ccc(-c2nc(=O)n(CCOC)c3c2oc2cc(-c4ccc5c(c4)CCN(C)C5)ccc23)cc1 +CCn1c(NC(C)C)nc2c(C3CCCN(C(C)=O)C3)csc2c1=O +CN1CCN(CCCc2cccc3c2[nH]c2c4ccc5ccn(C)c5c4c4c(c32)C(=O)NC4=O)CC1 +O=C(Nc1noc2ccccc12)N1CCN(c2nc(-c3ccccc3)cs2)CC1 +CC(C)OP(=O)(OC(C)C)C(Nc1ccc(CNC(=O)C23CC4CC(CC(C4)C2)C3)cc1)C(C)(C)C +COc1cc(OS(=O)(=O)c2ccc(NC(=O)NCCCl)cc2)cc(OC)c1OC +COc1ccccc1C(=Cc1coc2nc(=N)[nH]c(N)c12)C1CC1 +Clc1ccc(-n2nc3c4c(ncc3c2OCC2CC2)CCCC4)cc1 +COc1ccc(-c2cnc3c(N4CC(C)OC(C)C4)snc3c2)cc1OC +c1ccc(C(CCc2nc(CCNCCCCCc3ccncc3)c[nH]2)c2ccccc2)cc1 +Cn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +O=C(Nc1cccnc1)c1ccnc2[nH]c(-c3ccsc3)nc12 +O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCc3ccccn3)c2=O)cc1 +CC1CCC(NC(=O)c2cc3cccnc3n(CCCCCCO)c2=O)CC1 +C#CCN(c1ccc2ncc(-c3cnn(C)c3)nc2c1)c1c(F)c(OC)cc(OC)c1F +Cc1cccc(NC(=O)Nc2ccc(-c3cc4ccccc4n3C(N)=O)cc2)c1 +Cc1cc(C)n(-c2nc(Nc3ccccn3)cc(-n3cccn3)n2)n1 +CN1C(=O)CCC2(C)C3CCC4(C)C(C(=O)c5ccc[nH]5)CCC4C3CCC12 +CC1CCC(CN2C3=NCC(C4CCCCC4)N3CC2C2CCCCC2)CC1 +Cc1c(C2CN3CCN(C(=O)C4CCc5nc(-n6cnnn6)ccc54)CC3CO2)ccc2c1COC2=O +Cc1ccccc1OCc1n(CC(=O)OC2CC(C)CCC2C(C)C)c2ccccc2[n+]1C +CC(=O)OC1C(CO)OC(OCc2cn(-c3ccc(S(N)(=O)=O)cc3)nn2)C(O)C1O +N#Cc1cccc(-c2cc(Cl)ccc2C(Oc2cc(N3CCC4(CC3)CNC(C(=O)O)C4)nc(N)n2)C(F)(F)F)c1 +CCN(Cc1ccccc1)c1nc(O)nc(Nc2ccc3ncsc3c2)n1 +CNC(=O)c1ccc(C(=C2CC3CCC(C2)N3CCc2ccccc2)c2ccccc2)cc1 +Cc1cccc(-c2[nH]c(CNc3cc(C#N)cc(CN4CCOCC4)c3)nc2-c2ccc3ncnn3c2)n1 +Cc1cccn2cc(-c3ccc(NC(=O)CCN4CCCCC4)cc3)nc12 +COc1ccc(CN2C(=O)c3cccn3C3(CC(=O)NC3=O)C2=O)cc1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(C(C)(C)C)c2)CCC(N(O)C(C)=O)NC1 +Clc1ccc(-n2nc3c4c(ncc3c2OCc2ccccc2Cl)CCCC4)cc1 +Cc1ccc(N(CC(=O)NN=C2C(=O)Nc3ccccc32)S(=O)(=O)c2ccc(C#N)cc2)cc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3nc(-c4ccc(N5CCNCC5)nc4)ccc3OC)NC(=O)NC1=O)C2 +CC(C(=O)NC1CC1C)c1ccc(OC2CCN(c3nc(N(C)C)ncc3F)C2)cc1 +Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2c(F)cccc2F)cc1 +Cc1[nH]c2ccc(CCC(=O)O)cc2c1Cc1ccncc1 +O=C(O)CC1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1 +COC(c1ccc(C(=O)N(C)CCCCCCC(=O)NO)cc1)(c1cccc(F)c1)c1cccc(F)c1 +CCCCCCC#CC#CCCCCCCCC(=O)OCC1(CO)CC(=CCC(C)C)C(=O)O1 +CC(Oc1cc2sc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 +CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3cc[nH]c3)sc12 +O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)c1ccc(F)cc1 +CN(C)CCn1c(=O)c2ccc3c4c(nn3CCN(C)C)-c3ccccc3-n(c1=O)c24 +Cc1nc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)ccc1O +CC(C)CC(NC(=O)CC(c1ccccc1)c1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)O +Nc1noc2cccc(C(=O)Nc3cccc(CNC(=O)Nc4ccc(F)cc4)c3)c12 +NC(Cn1c(=O)c(-c2ccc(CO)cc2)cn(Cc2c(F)cccc2C(F)(F)F)c1=O)c1ccccc1 +CS(=O)(=O)c1cc(-c2cc(C(=O)O)cc3cc(-c4ccc(C(F)(F)F)cc4)ccc23)cs1 +CC(C)(C)NC(=O)C1CC(OCc2ccncc2)CCN1CC(O)C(Cc1ccccc1)NC(=O)OC1CCOC1 +CN(C)CCNc1ccc(Nc2nccc(-c3ccc(N4CCCC4)c(C#N)c3)n2)cn1 +NC(C(=O)N1CC(F)C(F)C1)C1CCC(NC(=O)OCc2ccccc2)CC1 +CCCn1c(NCc2cccc(Cl)c2)nc2nc(C3CCCC3)[nH]c2c1=O +CN(C(=O)c1c(-c2ccccc2Cl)noc1C1CC1)c1ccc(Cl)cc1 +O=C(CC1CC1)N1CCC2(CC1)CN(C(=O)Nc1ccc(C(F)(F)F)cc1)CCO2 +CC(C)NC(=N)c1cccc(-c2cccc(-c3cccc(C(=N)NC(C)C)c3)c2)c1 +CCc1nc(N)nc(N2CCC(O)CC2)c1C#Cc1cnc(C)c(NS(C)(=O)=O)c1 +O=C(NOCC1CC1)c1ccc(F)cc1Nc1ccc(I)cc1Cl +Cc1ccc(-c2nc3c(O)cccc3c(=O)[nH]2)cc1 +COc1ccc(Cc2cc3ccccc3cc2-c2cncc(OC)c2)cc1 +CC(OC1CCC2CNCC2C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1cc2cc(Nc3ccnc4cc(-c5ccc(CNCCOCCO)cc5)sc34)ccc2[nH]1 +COc1ccccc1N1C(=O)CSC1c1cccc(C(=O)NCCc2ccccc2)c1 +O=C(Nc1ccc(OC(F)(F)F)cc1)N1CCC2(CCN(C(=O)C3CCCCC3)CC2)C1 +CCN(C(=O)c1cn(C)c2ccccc12)c1ccnc(NC(C)c2ccccc2)n1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1cc2ccccc2s1)c1ccc(NS(C)(=O)=O)c(F)c1 +CC(C)Nc1nc(-c2ccc(C3(N)CC3)nc2)cc2ncn(C)c(=O)c12 +Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(N)cc(C(=O)O)c1 +COc1ccc(C2(C#N)CCN(CC(=O)NO)CC2)cc1OC +CCCCCCC1(c2ccccc2)CC(=O)C(SCc2ccccc2)=C(O)O1 +CCCS(=O)(=O)NCCOc1ccc2c(c1)C(C(C)(C)c1ccc(Cl)cc1)NCC2 +CCCN(CCC)C1COc2cccc(C(=O)NC(C)C)c2C1 +COc1ccc2c(c1)S(=O)(=O)Cc1c(C(=O)N3CCOCC3)nn(C3CCCN(CCN4CC(F)(F)C4)C3)c1-2 +CCCCCCCCCCCCCCC1C(=O)NC(CO)Cc2ccccc2N1C +Cc1nc(NCCCNc2ccnc3cc(Cl)ccc23)nc(-c2ccc([N+](=O)[O-])cc2)c1C(=O)OC(C)C +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(C=CCO)ccn23)c1 +CC(=O)c1nn(CC(=O)N2C(C(=O)NCCCOC(F)(F)F)CC3CC32)c2ccccc12 +COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(I)cc1 +CN(C)C(=O)c1cnn(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)c1 +Cc1cc(Nc2ccc(Cl)cc2)n2nc(S(C)(=O)=O)nc2n1 +Cc1nnc2n1-c1sc(C=Cc3ccc(C4CCCCC4)cc3)cc1C(c1ccccc1Cl)=NC2 +CCc1c(C(C#N)c2cccc3ccccc23)nc(SC2CCCC2)[nH]c1=O +Fc1ccc(CNc2nc(Oc3ccccc3)nc3nc(-c4ccco4)nn23)cc1 +C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(COCCO)c(F)c2F)c(F)c1 +O=C1C(=Cc2ccc(Cl)c(Cl)c2)SC(=S)N1NS(=O)(=O)c1ccccc1 +Cc1ccc(-n2nc(-c3ccc(NS(C)(=O)=O)cc3)cc2NC(=O)c2cnn3cccnc23)cc1 +O=C(CCNS(=O)(=O)c1ccc(C(=O)O)cc1)NO +CC(c1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1)N(C)C +CCCCCCC1=C(c2ccccc2)C2(OCCCC)CCCC2C1 +CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1 +CSCCC(N)CSSCC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)OCc1ccccc1 +CCn1c2ccccc2c2cc(NC(=O)c3cc(OC)c(OC)c(OC)c3)ccc21 +CC1CN(c2scnc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1ccc2ccncc21 +CC(C(=O)NCc1ccc(CC(=O)O)cc1)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 +Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)cn5)cc4=O)nc31)CCNCC2 +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1COC(=O)C1 +CC(=O)c1ccc(N2CCC(CC(=O)Nc3nc4ccc(C)cc4o3)CC2)cc1 +N=c1c(-c2nc3ccccc3[nH]2)cc(C(=O)c2cccs2)nn1-c1ccccc1 +Cc1cnc(C(=O)N2CC3CC(Oc4cnc(C(F)(F)F)cn4)C2C3)c(-n2nccn2)c1 +CC(C)NCc1ccc2c(c1)[nH]c(=O)c1cccn12 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(C3CCOC3)c2)CCCCC1 +Cc1c(Nc2c(C#N)cnc3sc(C=CC(=O)N4CCN(C)CC4)cc23)ccc2[nH]ccc12 +CCC(=O)Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12 +CCc1cc(S(=O)(=O)N2CC(c3ccccc3)NC2=O)ccc1NC(=O)OCC(C)C +CC1(C(=O)NCc2ccccc2)CC(C(=O)NCc2ccc(C(=N)N)cc2)n2c1c(Cl)nc(NC1CCC1)c2=O +CCCc1nc2c(C)cc(C(=O)NC(C)(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)Nc2nnn[nH]2)cc1 +CNc1nc(Nc2cc(F)c(C(=O)N(C)C)cc2OC)ncc1C#N +CC1CCN(CCCCCCCC(=O)Nc2cc(CO)cc(Nc3ccnc4cc(Cl)ccc34)c2)CC1 +COc1ccc(N2CCN(CCc3ccc(CN4C(=O)c5ccccc5C4=O)cc3)CC2)cc1 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+COc1cc2[nH]c(C)c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c(=O)c2cc1Cl +Cc1ccnc(N2CCCC(Cn3nnc4c(N)nc(C5CC5)nc43)C2)n1 +O=C(O)c1ccc2c(c1)nc(NC1CC1)c1nc(NCc3ccccc3)ncc12 +CN1CCN(Cc2ccc(Nc3ncc(Cl)c(-c4ccc(F)cc4S(=O)(=O)N4CCCC4)n3)cc2)CC1 +CCN(CC)CCNC(=O)c1ccc(NCCN(CC)CC)c2cc3ccccc3nc12 +COc1ccc(C(=O)Nc2ccc(Cn3cc4c(=O)[nH]cnc4n3)cc2)cc1 +Cc1cccc(Nc2nc(NC3CCCNC3)nc3cc[nH]c(=O)c23)c1 +Cn1c(CN2CCN(c3ccc(Cl)cc3)CC2)nc2ccccc21 +CN(C1CCc2c(CC(=O)O)c3cc(F)cc(F)c3n2C1)S(=O)(=O)c1ccc(F)cc1 +O=C(C=Cc1ccc2c(c1)CN(S(=O)(=O)C1CC1)C2)NO +CCn1ccc2cc(C=C3CCc4ccccc4C3=O)ccc21 +O=C1OC(=O)c2cc(NS(=O)(=O)c3cccc4nsnc34)cc3cccc1c23 +CC(C)=CC(=O)Nc1sc(Nc2ccc3ccc(F)cc3c2)nc1C(N)=O +Nc1nccn2c(C3CCC4CCCC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3F)c12 +CN1CC(NC(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)CC1=O +Cc1ccccc1COc1ccc(S(=O)(=O)N2CCN(C(=O)CN)C(C)C2C(=O)NO)cc1 +N#Cc1cc(-c2ccnc(Nc3ccc(C(N)=O)nc3)n2)cnc1N1CCC(F)C1 +COc1cc2cncc(Cc3coc4ccccc4c3=O)c2cc1OC +CCc1nc2c([N+](=O)[O-])c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 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+O=C(NCC1CCCC1C(O)CCc1ccccc1)c1ccc(OC(F)(F)F)cc1 +Nc1c2c(nc3c1C(c1ccncc1)c1ccc4cccnc4c1O3)CCCC2 +Cc1cc(C)c2oc3cc(=O)c4ncccc4c-3nc2c1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3OC)n1)CCN(CC(=O)N(C)C)CC2 +CN(C)C1CCC(Nc2ncnc3[nH]cc(C4CCCOC4)c23)CC1 +COc1ccc2[nH]c3c(c(C)c4c(O)nccc4[n+]3C)c2c1 +COc1ccc(-c2[nH]c3nc(N)[nH]c(=O)c3c2C#N)cc1 +Cc1cc(Nc2ncc(Br)c(NCC3CCCO3)n2)ccc1O +c1ccc(COc2ccc(-c3cnc4nnc(Cc5ccc6ncccc6c5)n4n3)cc2)cc1 +CC(C)n1ncc2c(C(=O)Nc3cccc(F)c3)cc(-c3cccs3)nc21 +CC(C)OC(=O)C1OC(n2cnc3c(N)ncnc32)C(O)C1O +COC(=O)CC(O)CC(O)C=Cn1c(C(C)C)cc(-c2ccc(F)cc2)c1-c1cccc(Br)c1 +CCC(NC(=O)CCc1ccc(-c2ccccc2)cc1)C(=O)NC(CCC(N)=O)C(N)=O +C=CCN1CC(C)N(C(c2ccc(C(=O)N(CC)CC)cc2)c2cccc(OC)c2)CC1C +O=c1[nH]nc(CCc2ccc(C(F)(F)F)cc2)cc1O +COc1ncc(-c2ccc3ncc4c(c3n2)n(C2CCN(C(C)=O)CC2)c(=O)n4C)cn1 +CCOC(=O)C1(Cc2ccc(OCc3cc(-c4ccccc4)nc4ccccc34)cc2)CC1C(=O)NO +O=C(Nc1ccc(N2CCN(C(=O)C3CC3)CC2)cc1)N1Cc2ccccc2C1 +Cn1c(N)c(C#N)c2cc(Oc3ccc(NC(=O)CN)cc3)ccc21 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+COc1cc2c(cc1OC)C(O)C(N1CCC(c3cccc4c3OCCO4)CC1)C2 +Cc1cc(NC(=O)c2ccc(CN3CCOCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C +COc1cc(OCc2csc(N3CCC(F)(F)CC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +Cc1cnc2n1CCN(C(=O)c1cccc(C(F)(F)F)c1Cl)C2 +N=C(N)NCCCC(NC(=O)CN1CCN(S(=O)(=O)c2ccc(N)cc2)CC1=O)C(=O)c1nccs1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NC(C)CS(N)(=O)=O)[nH]c3ccc(Cl)cc23)c1 +CCCCn1c(-c2ccc(O)cc2)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 +NC1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5ccccn5)c4)c23)CC1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC(C)c1ccccn1 +CC(C)C#CC(c1ccc(C2(C(F)(F)F)N=N2)cc1)N1CCC(CC(=O)O)CC1c1ccc(C(F)(F)F)cc1 +CCCCCC(O)C#Cc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(OCCC2CC2)cc1F +COc1ccc(C2CC2COc2cc(NCc3nnc(C)s3)n3nccc3n2)nc1 +CC(=O)Oc1cccc(C(=NNC(N)=S)c2cccc(Br)c2)c1 +O=C(Nc1cccc(C(F)(F)F)c1)n1ccc2cc(Oc3ncnc4c3CCNC4)ccc21 +CNCc1cnc2c(C#N)c(-c3ccc(OC)c(OC)c3OC)cc(-c3ccc(F)cc3)n12 +CN(C)c1ccccc1-n1nc(C2CCN(S(C)(=O)=O)CC2)cc1-c1ccc(Cl)cc1 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+CS(=O)(=O)c1ccc(-c2cn(CC(F)(F)F)nc2C2CCC(Cl)(Cl)CC2C(=O)NC2(C#N)CC2)cc1 +Cc1ccc(C)c(CN2CCC(C(=O)N(Cc3cc(Cl)c4c(c3)OCCCO4)CC(C)C)C2)c1 +COc1ccc2[nH]c(O)c(C3=Nc4ccccc4C3=O)c2c1 +CC(=O)c1ccc(OCc2ccc3c(c2)OCO3)cc1OC(CCC(=O)O)c1ccccc1 +Cc1nc(N(C)C2CCc3c(CC(=O)O)c4ccc(Cl)cc4n3C2)c2ccccc2n1 +NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)O)C1OC(CO)C(O)C(O)C1O +Cc1ccccc1-c1ccc(C(C)C(N)C(=O)N2CCC(F)C2)cc1 +CCCN(CCCc1ccc(F)cc1)CC(O)C(C)NC(=O)Nc1cc(CC)cc(-c2nnnn2C)c1 +CC12CCC3c4ccc(O)cc4CC(CCCCC#Cc4ccc5ccccc5c4)C3C1CCC2O +COc1ccc2c(c1)c1c(n2C)CCC1CNC(=O)C1CC1 +NC(N)=NC(=O)c1ccc2c(c1)C(O)c1cccc(CO)c1-2 +COc1cccc2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc12 +CC(C)Nc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br +CC(=O)NC(C)Cc1ccc(C#Cc2cnc(N(C)C3CCCC3)nc2)cc1 +CCCCNc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1C(F)(F)F +O=C(O)c1c(-c2ccccc2F)c2cc(Cl)ccc2n1Cc1ccccc1 +CCCc1ccc2cc1CN1CCN(CC1=O)Cc1cncn1Cc1ccc(C#N)c(c1)O2 +CN(C)c1ccc(F)c(CCNC(=S)Nc2ccc(Cl)cn2)c1F +COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 +NNc1nc(NC(C2CC2)C2CC2)c2ncn(C3C(O)C(O)C4CC43)c2n1 +CC12Cn3cnc(-c4ccc(F)cc4)c3C=C1CCCC2C(O)c1ccc(F)cc1 +COCCNC(=O)c1ccc(OCc2c(C3CCCCN3)noc2C)nc1 +COc1cc2cncc(Cc3ccc4nc(-c5ccc(CO)cc5)oc4c3)c2cc1OC +CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1)C(=O)c1ccc2nc(N(C)CCN(C)C)oc2c1 +CNC(=O)CN1C(=O)OC2(CCN(C3CCCCCC3)CC2)c2ccccc21 +N#Cc1ccc(S(=O)(=O)N2CCCc3ccc(Oc4cc(-c5nc(C6CC6)no5)cc(Cl)n4)cc32)cc1 +CN(c1ccc([N+](=O)[O-])cc1OC1CCCCC1)S(C)(=O)=O +O=C1c2ccccc2C(=O)N1CCOC(=S)N(C(=O)c1ccnc(Cl)c1)c1ccc(Cl)cc1 +CC(=O)OCC1OC(S(=O)(=O)NCCOS(N)(=O)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +CC(=O)c1cccc(C#Cc2c(N)ncnc2NC(C)c2nc3cccc(Cl)c3c(=O)n2-c2ccccc2)c1 +CC(=O)OCC(=O)Nc1scnc1C(=O)Nc1nccs1 +Cc1nc2sc(C(=O)NCc3ncccn3)c(N)c2c(C)c1Cl +CC(C)NS(=O)(=O)c1ccc(NC(=S)NC(=O)c2ccc(-c3ccccc3)cc2)cc1 +CNC(=O)c1ccc(CNC(=O)C2CCN(C(C)c3cccc4ccccc34)CC2)cc1 +O=C1Nc2ccccc2C12CC2c1ccc2c(C=Cc3ccncc3)n[nH]c2c1 +CNC(=O)c1coc(C(=O)CCCCCCc2ccccc2)n1 +O=S(=O)(CCC(S)CS)c1ccc(Oc2ccccc2)cc1 +CN(C)CCOc1ccc2c(C#N)cn(-c3ccc(C(=O)O)c(O)c3)c2c1 +CCc1ncnc(NC(C)c2cc3c(cc2O)CCCC3)c1Cl +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1ccccc1F)CC2 +Cc1ccc(C2(CCN(C)C)CC(c3ccccc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 +CN1CCC(c2ccc(Nc3nc4c(NCc5cccc(S(C)(=O)=O)c5)cccn4n3)cc2)CC1 +CN(C)CCNC(=O)c1cccc2nc3ccc4ccncc4c3nc12 +OC(CCN1CCN(CCCN(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccccc1 +CC(C)(C)NCC(O)COC(=O)c1ccc(C=O)cc1 +CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CC3CC2CN3)n1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2ccsc2)[nH]c1=O +Cn1cc(Br)c(C(=O)N2CCN(CC(=O)c3ccccc3F)CC2)n1 +OC(CNCc1ccco1)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21 +COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCn2ccc3ccccc32)CC1 +O=C(c1ncccc1-n1nccn1)N1CC2CC(Oc3ccc(C(F)(F)F)cn3)C1C2 +O=C(CC(F)(F)F)NCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +COC(=O)C(CO)Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O +Cc1cc(C(=O)N(c2ccccc2)c2ccccc2)nn1-c1ccccc1C(=O)N1Cc2ccccc2CC1CN +O=C(O)c1csc(-n2nc(-c3ccccc3F)cc2O)n1 +CN1C(=O)Nc2ccc(Br)cc2C12NC(=O)NC2=O +Cc1cc(S(=O)(=O)N(C)C)cnc1-c1ccc2c(c1)CCC(C)N2C(=O)c1ccc(O)cc1O +NC(CC(=O)N1CCN(Cn2nnc3ccccc32)C(=O)C1)Cc1cc(F)c(F)cc1F +CN1Cc2c(C(=O)OC(C)(C)C)ncn2-c2ccc(N=[N+]=[N-])cc2C1=O +CN(c1ncc(F)cn1)C1CCc2c(CC(=O)O)c3cc(Cl)ccc3n2C1 +N#Cc1cnc2ccc(NCc3cccc(N)c3)cc2c1Nc1ccc(F)c(Cl)c1 +COc1ncc(Nc2nc(CN3CCOCC3)ccc2-c2nc(C)nc(N)n2)cc1F +O=C(O)c1ccc(-c2c(C#Cc3nc4ccccc4[nH]3)nc3c(N4CCOCC4)ccnn23)cc1 +O=C(Nc1cccc(C(c2ccc(C(=O)N3CCC3)cc2)N2CCN(Cc3ccc(F)cc3)CC2)c1)C1CC1 +CC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(Br)n3)CC3CC32)c2ccccc12 +Cc1ccccc1-c1nc2ccn(Cc3ccc(Br)cc3)cc-2n1 +CN(c1nc2ccccc2o1)C1CCN(CC2=CCC3CC2C3(C)C)CC1 +Cc1cccc(-c2cnc(NC3=NCC4(CN5CCC4CC5)O3)nc2)c1 +Cc1cccc(NC(=O)NC(CSCc2ccccc2)C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CN(C)CC(Cc1cccc(C(F)(F)F)c1)c1cccc(OCCNS(=O)(=O)c2cnn(C)c2)c1 +CC(NC(=O)C1CC(F)CN1C(=O)Cn1nc(C(N)=O)c2ccccc21)C1CC1(Cl)Cl +CC(NC(=O)Nc1cc2[nH]nc(OCCC3CCCCN3)c2cn1)c1ccccc1 +COc1ccc(OC)c(Sc2ccc3nnc(-c4ccn(C)n4)n3n2)c1 +COc1cccc(-c2ccc(CNC(=O)C3CC3c3ccccc3)c3cnccc23)c1 +OC(COc1cccc2[nH]ccc12)CN1CCC(c2cc3ccccc3s2)CC1 +CCCCc1nnc(OCc2ccccc2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +CCCCn1c(=NC(=O)c2cc(C(F)(F)F)ccc2OCC(C)(C)O)sc2ncccc21 +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(C5CCN(CC(C)O)CC5)cc4)c3)c(OCCCF)cc21 +COc1ccc(C2c3nc(NC(C)C)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)c(O)c1 +COC(=O)C=Cc1cc(OC)c2c(c1)C(COC(=O)c1cc(O)c(O)c(O)c1)C(c1ccc(O)c(OC)c1)O2 +CONC(=O)c1ccc(C)c(Nc2ncnn3cc(NC(=O)OC(C)C)c(C)c23)c1 +O=C(Cc1cccc(Cl)c1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1 +CCCc1cc(Oc2ccccc2OCCn2ccc(=O)[nH]c2=O)c(C)c2cc(C#N)ccc12 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(C(O)c5ccccc5)C4)cc23)ccn1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCCO)c3)s2)nn1 +CCOc1ccc(-c2nc(NC(=O)C(N)COCc3ccccc3)sc2-c2cc(OC)c(OC)c(OC)c2)cc1 +Cc1ccc(-c2noc(C3CC(O)C3)n2)cc1NC(=O)c1cnc2ccc(F)cn12 +Cc1ccc(Oc2ccc(NC(=O)CNc3ccccc3N3CCCC3=O)cc2)cc1 +COC(=O)C1C2CCC3CCC1N(CC2=Cc1ccc(-c2cccs2)cc1)C3 +CN(C)C(=O)N1CC2CC(NCC(=O)N3CCCC3C#N)CC2C1 +CN(C)CCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4cccnc4)cc3)nc21 +CN1CCN(c2nccnc2Oc2ccc(Nc3ccccn3)cc2)CC1 +CC(C)C(CO)NCc1nc(-c2ccc(F)cn2)ccc1F +CCOCC(COCC)Oc1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +O=C(NCC#Cc1ccc2nccc(OCC3CCNC3)c2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +CCOc1ccc2nc(C)cc(N3CCN(C(=O)c4ccco4)CC3)c2c1 +CC(C(=O)N(C)C1CCCCC1)C1(O)CCN(CCc2ccccc2Cl)CC1 +N#Cc1ccc(C(c2cccnc2)N2CCC(NC(=O)c3ccccc3F)CC2)cc1 +CC(=O)Nc1cc(C(=O)NC(C)c2ccc(OC3CCN(c4ccnc(OC(C)C)c4)C3)cc2)ccn1 +O=C(O)CC(O)CC(O)CCn1c(C(F)(F)F)nc(-c2ccc(C(F)(F)F)cc2)c1-c1ccc(F)cc1 +CN1CCN(c2nc3ccccc3c(-c3ccccc3)c2CCOC2CCCO2)CC1 +O=C1Cc2c([nH]c3ccc(Br)cc23)-c2ccc(O)cc2N1 +Cc1ccc2ccccc2c1-c1cccc(COc2ccc3c(c2)OCC3CC(=O)O)c1 +CC1CCC2C(CNCCN)=C(C(F)(F)F)OC3OC4(C)CCC1C32OO4 +CC1CCNC(=O)c2cc3ccc(C(=O)Nc4cc(Cc5ccccc5)no4)nc3n21 +Cc1ncc([N+](=O)[O-])n1CCN1CCN(C(c2ccccc2)c2ccccc2)CC1 +CC1CN(c2ccc(F)cc2)CCN1c1nc(-c2ccncn2)cc(=O)n1C +N#Cc1ccc(Nc2nccc(C(=NO)c3ccccc3)n2)cc1 +CC(C)CN(CC(C)C)C(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +CN(C)C1Cc2ccccc2C(c2ccc(C(F)(F)F)cc2)C1 +O=C1C(N2CC(c3ccc(O)cc3)C2)CCN1Cc1ccc(F)cc1 +CCc1ncnc(-c2ccc(C(=O)N3CCn4c(C)cnc4C3)c(F)c2)c1C#Cc1ccc(N)nc1 +COc1cccc(NC(=O)Nc2nc(-c3cc4ccccc4o3)cs2)c1 +CC(Oc1cc(-n2cnc3cc(-c4ccncc4)ccc32)sc1C(N)=O)c1ccccc1Cl +CC(C)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CC1CN(C(=O)N2Cc3c(C(=O)OC(C)(C)C)ncn3-c3cccc(Cl)c32)CC(C)N1 +CCC(c1nc2c(cnn2C(C)C)c(=O)[nH]1)N1CC(Oc2ccc(C)cc2)C1 +Cc1c(Nc2c(C#N)cncc2-c2ccc(OCCN3CCN(CCO)CC3)cc2)ccc2[nH]ccc12 +Cc1cc(=O)oc2c1ccc1sc(C(=O)c3ccccc3)c(-c3ccccc3)c12 +CCc1nc(-c2cc(-c3ccc(CO)cc3)c3c(N)ncnn23)cs1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c1ccc(C(=O)O)cc1 +O=C(O)c1ccc(NC(=O)C(Cc2ccccc2)CC(Cc2ccccc2)C(=O)O)cc1 +CC12CCC3C(C(Sc4cccc5ccccc45)CC4=CC(=O)CCC43C)C1CCC2=O +COCCCNC(=O)C(C)CC(O)C(N)CC(Cc1ccc(OC)c(OCCCOC)c1)C(C)C +O=C(NCC1CC(F)CN1)c1ccc(-c2cnc3ccc(NCCCCCF)nn23)cc1F +CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1 +COc1ncc(-c2cc3c(C)nc(N)nc3n(C3CC(OCC(N)=O)C3)c2=O)cn1 +N#CCc1c(C(=O)Nc2cnc3ccccc3c2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2cnc(Oc3cccc(F)c3)nc2)cc1 +O=c1[nH]c(=NOCCCc2cccnc2)ccn1C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O +Cc1cccc(CNC(=O)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)c1C +COC(=O)C(Nc1cc(CS(=O)(=O)C=Cc2c(OC)cc(OC)cc2OC)ccc1OC)c1ccc(Br)cc1 +COc1ccc(C(=O)NCc2ccc(OC)cc2C(F)(F)F)cc1 +Cc1cn(C2CC(O)C(CNC(=S)Nc3ccc(Cl)c(C(F)(F)F)c3)O2)c(=O)[nH]c1=O +COc1cc(-c2nncn2C)ccc1Nc1ncc2c(C)cnc(NCC(C)(C)C)c2n1 +Cc1cc(C)cc(NC(=O)c2sccc2SCc2ccncc2)c1 +CC(C)NC(=N)c1ccc(-c2cccc(-c3ccc(C(=N)NC(C)C)cc3)c2)cc1 +CCN(c1cc(-c2cnn(C)c2C)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2ccnc3c(Nc4ccc(C(F)(F)F)cc4)nsc23)c1 +CC(Nc1ncnc(N)c1C#Cc1ccc(F)cn1)c1nc2cccc(Cl)c2c(=O)n1N1CCNCC1 +Cn1cnc2cc(-c3ccc4c(c3)CC(=O)N4)nc(NC3CCOC3)c2c1=O +Cc1nc(C(=O)Nc2ccnc(Cl)c2)c(C)n1-c1ccc(F)cc1 +CN1CCN(c2nc3ccccc3c3c2CC2CCC3C2)CC1 +CN(C)CCn1cnc2c(c1=N)C(c1ccccc1)c1ccc3ccccc3c1O2 +NCCCCCCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=C(c1cn2ccn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2n1)N1CCCCC1 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+CC(C)N1CCN(C(=O)N2Cc3c(NC(=O)c4ccccn4)n[nH]c3C2(C)C)C(C)C1 +O=C(c1ccc(Cl)cc1)C1CCN(c2ncnc3sccc23)CC1 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCCCCCC(=O)NO +CCN(CC)CCN1CCC2(C)c3cc(O)ccc3CC1C2C +O=C(NCC1CCN(c2ccncc2)CC1)c1ccc(I)c(OCCc2ccc(Cl)cc2Cl)c1 +O=C(Nc1n[nH]c2nc(-c3ccc(O)c(Br)c3)ccc12)C1CC1 +COCCOC(=O)N1CCC(C(NS(=O)(=O)c2ccc(-c3ccc(SC)cc3)cc2)C(=O)O)CC1 +NC(=O)c1cnc(-c2ccccc2)nc1Nc1ccc(CC(=O)NCC2CC2)cc1 +CC(Oc1ccc(N2CCC3(CCC(O)(CN4CCCC4=O)CC3)C2=O)cc1)C(F)(F)F +O=C1CCC(CCN2CC(N3CCOCC3)C2)(c2ccc(Cl)c(Cl)c2)CN1CC1CCCCC1 +Fc1ccc(C(OCCN2CC3CC(C2)N3Cc2cc3ccccc3o2)c2ccc(F)cc2)cc1 +O=C1N(CCCCCCCCO)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1CCCCCCCCO +CC(C)(C)Cc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(Cc1ccc(Oc3ccc(F)cc3)cc1)CC2 +O=C1CCc2cc(-c3cncc(F)c3)cc3c2N1CC3 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(F)cc(F)c1 +O=C(NC1CCCC1Nc1ncc(C(F)(F)F)cc1F)c1ncccc1-c1ncccn1 +C#Cc1cccc(Nc2ncnc3ccc(NC(=O)Nc4ccc(N(CCCl)CCCl)cc4)cc23)c1 +CS(=O)(=O)c1ccc(C2=C(c3ccc(CO)cc3)C(=O)OC2)cc1 +O=C1NC2(CCc3ccccc32)C(=O)N1CCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +COC(C)(C)CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C +COc1cccc(COc2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2C(F)(F)F)c1 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(Cl)ccnc12 +COCCCOc1cc(C(=O)N(CC2CNCC2OCc2cccc(-c3cccc(C)c3)c2)C(C)C)ccc1OC +COc1cc(CCCC=NN=C(N)N)cc(OS(=O)(=O)c2ccccc2Cl)c1 +CCOCC1CCC(COC2CCC(C(=O)O)CC2)N1C(=O)Cc1ccc2nc(Nc3ccccc3C)oc2c1F +NCCNc1cc(N2CCN(C(=O)C3(c4ccccc4)CCC3)CC2)nc2ccccc12 +CC(C)(C(N)C(=O)N1CC(F)CC1C#N)S(=O)(=O)Cc1ccc(F)cc1 +COC(=O)c1[nH]c2cccc(OC)c2c1C(=O)c1ccc(Cn2c(C)nc3cnccc32)cc1 +CCCCC(=O)Nc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 +Cn1c(=O)[nH]c2cc(N3CCCC(C)(N)C3)n(Cc3ccccc3)c2c1=O +CCOC(=O)N1C(=S)N=C(C)C(=C(O)OCCN(C)Cc2ccccc2)C1c1ccccc1C(F)(F)F +Cc1ccn(CC(=O)N2CCN(C(=NC#N)Nc3ccccc3C)CC2c2ccccc2)n1 +NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C=CC(=O)Nc2ccc(Cl)cc2)cc1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(NC3(C)CCCCC3)c2n1 +COc1cc(OC)c(S(=O)(=O)N2c3ccccc3CCC2C)cc1NC(=O)C=CC(=O)O +COC1CN(CCCc2cccc(NC(=O)C3CC3)c2)CCC1n1c(C)nc2cc(C)ccc21 +Cc1nn(C2CCCC2)c(C)c1S(=O)(=O)NC(C)CNc1cccc2c1cnn2-c1ccc(OC(F)(F)F)cc1 +CC(C)Nc1nc(-c2ccc3c(c2)S(=O)(=O)CC(=O)N3C)cc2ncn(C)c(=O)c12 +Cc1ccc(S(=O)(=O)N(C)c2ccccc2C(=O)c2ccsc2)cc1 +O=C(c1nnc(-c2ccccc2)o1)N1CC(Oc2ccc(CN3CC4(COC4)C3)cc2)C1 +CC1CN(c2ccc(F)c(NS(=O)(=O)c3ccc(-c4cccs4)cc3)c2)CC(C)N1 +CCc1[nH]cnc1CNc1cc(Cl)c2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1 +Cc1nc(-c2[nH]c(CNc3cccc(C(N)=O)c3)nc2-c2ccc3ncnn3c2)ccc1F +CC1(C)C(NC(=O)c2ccn(CCO)n2)C(C)(C)C1Oc1ccc(C#N)c(Cl)c1 +CC(C(=O)NCc1ccc(C(C)(C)C)cc1N1CCN(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +CN1C(=O)C(NC(=O)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)N=C(c2ccccc2)c2ccccc21 +COc1c(C(=N)N)cccc1-c1cc(-c2ccc(C(=N)N)cc2)no1 +COc1ccc(CCN2C(=S)NC3c4cccc(OC)c4OC2(C)C3C(=O)Nc2ccc(C)cc2C)cc1OC +COCc1cc(NC(=O)Cc2nc(N3CCOCC3)cc(=O)[nH]2)ccc1F +CC1(O)CCC2(C)C(CCC3C4CC=C(c5cccnc5)C4(C)CCC32)C1 +CC(C)C(CO)Nc1nc(Nc2ccc(-c3cccnc3)cc2)c2ncn(C(C)C)c2n1 +CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)nc(CN(C)C)cc21 +COC(C)(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(C(=O)O)cc2)cc1F)C(F)(F)F +CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1ccc(C)cc1 +CC(C)c1ccccc1N1CCN(CCCCCC(=O)NCc2ccc(C#N)cc2)CC1 +CCC(C)C(=O)N1CCC(C(=O)NCc2ccc(OC)cc2C(F)(F)F)CC1 +COc1cc2c(cc1OC)C(=O)C(Cc1cc[n+](Cc3ccccc3)cc1)C2 +Cc1ccc(C(CCN(C)C)NC(=O)c2cccc(-c3ccc(Cl)cc3)c2)cc1 +O=S(=O)(O)CCNc1c(Br)cccc1Nc1ncnc2ccncc12 +CC(C)CN(C(CO)CCCCNC(=O)C(Cc1ccccc1Cl)NC(=O)c1ccncc1)S(=O)(=O)c1ccc(N)cc1 +Cc1ccc2[nH]c(-c3sc4nc(C)ccc4c3N)nc2c1 +OC1(CC2CCCN3CCCCC23)c2ccccc2Sc2ccccc21 +CCN(CC)C(=O)c1cc2c(s1)C(=O)c1c(O)cccc1C2=O +COc1cscc1C(=O)N1CCC(F)(CNCc2ccc(C)cn2)CC1 +O=C(O)c1cccc2c(=O)cc(-c3cccc(C=Cc4ccc5ccccc5n4)c3)oc12 +COc1ccc(N2CCN(CCCCc3c[nH]c4ccc(C(N)=O)cc34)CC2)c(OC)c1 +COc1ccccc1-c1ccc2cnc(Nc3cccc(N4CCOCC4)c3)nn12 +Cc1ccc(Oc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCCn1ccnc1[N+](=O)[O-] +COc1ccc(CC2CN3C(=NCC3C)N2CCC2CC3CCC2C3)cc1 +Cc1cccc(-c2nsc(SCC(=O)N3CCCC3)n2)c1 +CC1CCCN1CCCOc1ccc(-c2nn(C(C)C)c(=O)c3ccsc23)cc1 +CC1(CC(=O)O)CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(CS(C)(=O)=O)C2CC2)C1=O +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(-n3cccn3)cc2)nc2ccc(Cl)cn12 +Cc1cc(CC(NC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2cccc(Br)n2)cc2cn[nH]c12 +O=C(O)CCC(NC(=O)c1ccc(CNc2ccc3ncnc(O)c3c2)cc1)C(=O)O +COc1cc2nccc(Oc3ccc4c(C(=O)NC5CC5)cccc4c3)c2cc1C(N)=O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4cccc(F)c4)nc23)N1 +N#Cc1c(C2CCCNC2)cc(-c2c(O)cccc2OCC2CC2)nc1N +COc1cc(-c2ccc3ncc(C(C)=O)c(NC4CCC(CCN(C)C)CC4)c3c2)cc(Cl)c1O +O=C(NC1CCCN(c2nc(Cl)nc3cc(N4CCOCC4)ccc23)C1)c1cscn1 +CC(=O)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccc(F)cc21 +CCCCc1nc(Cl)c(C(=O)OC(C)OC(C)=O)n1Cc1cccc2c1ccn2-c1ccccc1-c1nn[nH]n1 +Cc1c(Cc2ccc(C(=O)O)cc2S(=O)(=O)c2ccccc2)c(-c2ccccc2)nn1CC(=O)O +CSc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2C1CCC1 +COC(=O)NC(C)CNc1nccc(-c2nc(C(C)(C)C)[nH]c2-c2cc(C)cc(NS(=O)(=O)C(C)C)c2)n1 +NC(=O)N1CCCc2cc(-c3cncc(OCCN4CCOC4=O)c3)cnc21 +O=C(c1ccc(Nc2ccc(Cl)cc2)nc1)N1CCCCCC1 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccc(S(=O)(=O)N4CCOCC4)cc3)cc21 +Fc1ccc(C2(c3ccc(F)cc3)CNC(c3ccccc3)=N2)cc1 +CC(C)COc1cccc(C(C)Nc2nccc(N3C(=O)OCC3C(C)O)n2)c1 +CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(NC(=O)C(Cc2cccs2)n2cccc2C(=O)O)cc1 +CC(C)=C1CC(CO)(COC(=O)COc2ccc(C#Cc3ccc(C)cc3)cc2)OC1=O +C=CC(=O)Nc1cccc(-n2c(=O)cnc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +CCn1cc(-c2cc3c(-c4cc(C(C)C)ccn4)n[nH]c3cn2)cn1 +Cc1cnc(Cl)c(-c2c[nH]c3ncnc(N4CCCC(C)C4)c23)c1 +CCCCC(CN(O)C=O)C(=O)NC(CC(C)C)C(=O)N(C)C +COc1cc(Nc2c(C#N)cnc3cc(-c4cccc(CN5CCOCC5)c4)c(OC)cc23)c(Cl)cc1Cl +CC(C)(C)c1cn(CC2CCCO2)c(=NC(=O)c2cc(C(F)(F)F)ccc2ON=C2CCCC2)s1 +CN(C)C1(CNCCc2ccccc2F)COc2ccccc2OC1 +CCCCN1CC(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(OCc3ccccc3)CN2)C(CC)C1=O +O=C1NC(=O)C(c2cnc3cccnn23)=C1c1cn2c3c(cccc13)CN(C(=O)N1CCCCC1)CC2 +COC(=O)CSc1nnc(Cc2csc(NCCC(=O)O)n2)n1NC(=O)c1ccc(Cl)cc1 +CCc1c(-c2nnc(C(C)(C)C)s2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1 +NC1(c2ccc(-c3nc4c(Br)cc(Cl)cn4c3-c3ccccc3)cc2)CCC1 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+CCc1nc(Oc2cc(C)ccn2)c(CC)nc1NC(c1ccccc1)C(C)C +O=C(CCOc1cccnc1)Nc1ccc2nc3c4[nH]c5ccccc5c4ccn3c(=O)c2c1 +N#Cc1c(N)cc2c(c1N)Cc1cc3c(cc1O2)OCCO3 +COc1cccc(-c2c(C(=O)NN)[nH]c3ccc(S(N)(=O)=O)cc23)c1 +CSCCCNC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2C(N)CC(C)C)CC1 +O=c1ccc2cc(OCC(=NO)c3ccccc3)ccc2[nH]1 +Cc1ccnn1-c1ccc(C(=O)N2CCC(F)(F)C(=CC(=O)NCc3ccccn3)c3ccccc32)c(Cl)c1 +Cc1cc(C(C)Nc2ccccc2C(=O)NO)c2nc(N3CCOCC3)cc(=O)n2c1 +O=S(=O)(c1ccc(Cl)cc1)C1(c2cc(F)ccc2F)CCC(CI)CC1 +CN1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +c1ccc(COCCCOc2ccc(C3C(CSc4ccncc4)CNCC3OCc3ccc4ccccc4c3)cc2)cc1 +CC(C)CCN1C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)C2CCCCC21 +COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2cccc(C(C)(C)c3nnn[nH]3)c2)n1 +COc1ccc(-c2nc(CSc3cc(C)cc(C)c3)nc3ccsc23)cn1 +Cc1ccc(S(=O)(=O)NC(Cc2c[nH]c3ccccc23)C(=O)Nc2ccc(C(=O)NO)cc2)cc1 +CN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc4c(c3)NC(=O)CO4)nc2n1 +Cc1ccc(C(=O)C2CCN(CC(=O)NCc3nc4c(c(=O)[nH]3)COCC4)CC2)cc1 +CN1CCOCC1c1nc(C(=O)NCCc2ccccc2)c(O)c(=O)n1C +O=c1ccc(-c2ccc(Cl)cc2)cn1C(CN1CCCC1)c1ccccc1 +CN1CCC2(CC1)Oc1ccccc1C1CC(c3ccc(Cl)cc3)=NN12 +Cc1cc(O)ccc1-n1cnc2cc(O)cc(O)c2c1=O +CN(C)c1ccc(-c2cn(-c3ccc(I)cc3)nn2)cc1 +O=C1CCC(c2ccc3nc(-c4ccccc4)oc3c2)=NN1 +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CCc2nc(C(C)(C)C)ncc2C1 +Cn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(-c4cnn(C)c4)c2)CC3)cn1 +CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCS(=O)(=O)CC2)c1 +O=C(NC1c2ccccc2CC1O)C(Cc1ccccc1)CC(O)CN1C(=O)N(Cc2cccnc2)CC1Cc1ccccc1 +Cc1cccc(S(=O)(=O)NC(CNC(=O)Cc2cc(-c3ccc(C(=N)N)cc3)no2)C(=O)O)c1 +NCCCNC(=O)c1cccc(Nc2nccc(-c3cccnc3)n2)c1 +O=C(OCC1CCN(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)CC1)c1c2n(c3ccccc13)CCCO2 +Cc1cccc(NC(=O)CN2CCC(c3cccc(C#N)n3)CC2)c1 +Cc1n[nH]c(C)c1CC(=O)NCc1cccc(Cl)c1C +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(C2CCC(O)CC2)C3=O)c(OC)n1 +COCc1nsc(N2CCN(C(=O)C3CNC(C(=O)N4CCCC4)C3)CC2)n1 +CC1(C)c2[nH]nc(NC(=O)c3cccs3)c2CN1C(=O)N1CCN2CCCC2C1 +Cc1ccc(-n2nccn2)c(C(=O)N2C(C)COC2Cn2cc(-c3ccc(F)cn3)cn2)c1 +CCN(CC)CCNc1n[n+]([O-])c2ccc(C(C)(C)C)cc2[n+]1[O-] +Cn1ncc(NC(=O)c2csc(-c3c(F)cc4c(c3F)OCC4)n2)c1C1CCC(N)C(F)CO1 +COc1cccc(Cl)c1-c1cc2[nH]c3ccc(O)cc3c2c2c1C(=O)NC2=O +CCc1nn(Cc2ccc(-c3nc4cc(F)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O +CC(=O)C(C)N1CCC(NC(c2ccc(Cl)cc2)c2cccnc2)CC1 +CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(Cl)c23)c1 +S=C(NCCCn1ccnc1)Nc1ccc(OCc2ccccc2)cc1 +NS(=O)(=O)c1ccc(CCn2c(=S)[nH]c3ccccc3c2=O)cc1 +COC(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)cc3)ncc12 +COc1ccc(-c2sc3ccccc3c2C(=O)c2ccc(OCCN3CCCCC3)cc2)cc1 +C=CC(=O)N1CCC(Oc2cc3c(Nc4cccc(C=C)c4)ncnc3cc2OC)CC1 +COc1cccc(OC(C)c2cc(C(=O)N(C)CCO)cn3c(=O)cc(N4CCOCC4)nc23)c1 +COc1ccc(C(=O)Nc2ccc(F)c(C3(C(F)F)N=C(N)OC4CC43)c2)nc1 +Cn1nc(CC(=O)Nc2cccc(-c3ccc(C#N)cc3)c2)c2ccccc2c1=O +COc1cccc(-c2cnc3c(NCc4ccc(S(N)(=O)=O)cc4)nccn23)c1 +CSC1COCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cn2)cc1 +Cc1nc2cnccc2n1-c1ccc(C(=O)NCc2cccc(C(=O)Nc3ccc4c(c3)CN(C)CC4)c2)cc1 +Cc1cc(COc2ccc(NC(=O)C3CN(C)CCC3C(=O)NO)cc2)c2ccccc2n1 +CCCCc1ccc(OCCC(NC(C)C(=O)O)C(=O)N2NCCCC2C(=O)NC)cc1 +CCCCn1cnc2c(NCc3ccc(C)cc3)nc(C#N)nc21 +CCCCC(c1ccc(C(F)(F)F)nc1)N1CCC(CC(=O)O)CC1c1ccc(C(F)(F)F)cc1 +COc1ccc(C(C#N)(CCCN2CCc3cc(OC)c(OC)cc3C2)Sc2ccc(C)cc2)cc1OC +Cc1ccc(C(=O)C=Cc2ccc(O)c(O)c2)c(C)c1 +CN(CCCc1ccc(C(F)(F)F)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CCNCC2)n1 +Cc1cccc2cc(Cn3nc(I)c4c(N)ncnc43)n(-c3ccccc3O)c(=O)c12 +COc1ccc(C(C(=O)NC(C)(C)C)N2C(=O)C(C3Cc4ccccc4C3)NC(=O)C2CC(C)C)cc1 +COc1ccc(S(=O)(=O)N(CC(=O)NCC2CCCCC2)C(CCSCc2ccccc2)C(=O)NO)cc1 +CCN(CC)CCN1C(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +COc1cc2nc(S)n(CCc3ccc(S(N)(=O)=O)cc3)c(=O)c2cc1OC +COC12CCC3(CC1C(C)(O)c1cccs1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+]1(C)CCCCC1 +COc1ccncc1-c1ncccc1CN(C(=O)c1ccc(-c2ccc(C#N)cc2)o1)c1ccc(N2CCNCC2)cc1 +CCNC(=O)C1OC(n2cnc3c(N)nc(C#Cc4ccc(CCC(=O)OC(C)(C)C)cc4)nc32)C(O)C1O +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(c2ccccc2)C1 +CC(C)=CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CC(=O)N1CCCCC1)c(=O)n2C +CCCCN=C(N)c1ccc(C(=O)NC(CC)C(C)(C)C(=O)N2CCC(CC(=O)O)CC2)c(F)c1 +Cc1occc1C(S)=Nc1ccc(Cl)c(CNOC(C)(C)C)c1 +O=C(CN(CCNc1ccnc2cc(Cl)ccc12)C(=O)c1cnccn1)NC1CCCCC1 +COC(=O)N1CCC(OC)(c2nc(C)c(-c3cc(C(=O)N4CC(c5ccc(C#N)cc5)C4)ccc3C)[nH]2)CC1 +COc1ccc(C2C(c3ccc(O)cc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1O +Fc1cccc(C2CCN(CCCNc3nc4ccccc4n3-c3ccc(Cl)cc3)CC2)c1 +O=C1C2Cc3c([nH]c4ccccc34)C(c3ccc4c(c3)OCO4)N2C(=O)CN1C1CCN(CCc2ncc[nH]2)C1 +CCOC(=O)c1cnc(N2CCN(C(=O)NS(=O)(=O)c3ccccc3C)CC2)c(Cl)c1 +COc1ccc(CN(C)C2(c3ccccc3)CCC(c3ccccc3)(N(C)C)CC2)cc1 +Nc1nc(OC(c2ccc(Cl)cc2-c2ccc(Cl)cc2)C(F)(F)F)cc(N2CCC3(CC2)CNC(C(=O)O)C3)n1 +Clc1ccc(CN2CCC(c3cc(-c4ccc(Cl)cc4)on3)CC2)cc1 +NC1CN(c2ccc3nnc(-c4ccc(F)cc4)n3n2)CCC1c1cc(F)c(F)cc1F +COCC1CC2CCC(C1)N2c1nc(N2CCC(C(N)=O)C2)nc2scc(-c3ccccc3OC)c12 +COc1cccc(C2CN3CCCC3c3cc(OCCCN4CCCCC4)ccc32)c1 +CCC1CC(O)=C(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)C(=O)N1Cc1ccc(F)cc1 +CC1CC2(C)CC(=O)C1C1C(=O)N(OCCCN3CCN(c4ccccc4)CC3)C(=O)C12 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+O=C(NCC1CCNCC1)c1c(F)cccc1-c1cccc(Cl)c1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(N(C)C)cc1 +Cc1cccc(S(=O)(=O)c2c(C(N)=O)[nH]c3ccc(Cl)cc23)c1 +COc1ccc(OC2OC(CO)C(OC3OC(CO)C(O)C(O)C3O)C(O)C2O)cc1 +CC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(NCc5cccnc5)ncnc4c23)CO1 +NC(=O)C(Nc1ccccc1[N+](=O)[O-])c1c(Cl)cccc1Cl +Cc1nc2ccccn2c1-c1ccnc(Nc2ccc(Cl)cc2)n1 +CCOc1ccc(-n2c(C)c3c(C)nnc(CCC(C)C)c3c2C)cc1 +CN(CCCN(C)CCCC(O)(c1ccccc1)c1ccccc1)CCCC(O)(c1ccccc1)c1ccccc1 +Cc1ccccc1COc1ccc(S(=O)(=O)N2CCN(Cc3ccccc3)C(C)C2C(=O)NO)cc1 +Cc1cnccc1-c1nc(C)c2c(C)nc3c(F)cc(OC(F)F)cc3n12 +O=C(NC(c1ccc(Cl)cc1)c1cnccn1)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1 +COc1ccc2c(c1)C1(CC1c1ccc3c(C=Cc4ccc(CN5CCOCC5)cc4)n[nH]c3c1)C(=O)N2C +CN1CC=CCCOc2cccc(c2)-c2ccnc(n2)Nc2ccc(OCCN3CCCCC3)c(c2)C1 +O=S(=O)(c1cccc(-c2ccccc2)n1)N1CCCCC1c1nnn[nH]1 +O=C1COc2ccc(CNC3CCN(CCn4c(=O)ccc5ncc(Oc6cccnc6)cc54)CC3F)nc2N1 +O=c1oc2cc(S(=O)(=O)Nc3ncns3)ccc2n1Cc1ccccc1 +Nc1cc(-c2ccccc2)nc2c1cnn2Cc1ccncc1 +c1ccc(CCNc2ccc3nnc(-c4ccccc4)n3n2)cc1 +CCCCCC(O)C=CC1C2CC(OO2)C1CC=CCCCC(=O)O +COc1ccc(-c2ccc(CCNC(=O)c3ccc4c(c3)C3(C)CCN(CC5CC5)C(C4)C3C)cc2)cc1OC +COc1ccc(-c2cc(=O)c3cc(OC)c(OC)c(OC)c3o2)cc1O +Cc1nc(Nc2cc(C#N)ccn2)cc(C2CCCN(C(=O)c3ccccc3)C2)n1 +N#Cc1cc(COc2ccc3[nH]c4c(c3c2)CCNC4CC(=O)O)cc(OC(F)(F)F)c1 +Cc1cnnc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)n1 +Cc1cccc(NC(=O)CN2CCC(c3cccc(F)c3)CC2)c1 +Oc1cc(CCCc2ccccc2)ccc1Oc1ccc(Cl)cc1Cl +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C(O)C(I)I +O=C(CCCCCCC(=NO)c1ccc(-c2ccccc2)cc1)NO +COc1cc2cc(CO)c(CO)c(C3=CCN(C)C(=O)C3)c2cc1OC +Cc1ccccc1-c1nc2cc(-c3nc4cc(N5CCN(C)CC5)ccc4[nH]3)ccc2[nH]1 +CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cn2)C(=O)O3)cc(OCC)c1-c1ccc(F)cc1 +Nc1ncnn2c(CN3CCCC(O)C3)cc(-c3cc(F)c(CO)c(F)c3)c12 +N#Cc1cnc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)cc1OC1CN2CCC1CC2 +O=C(c1cc2n(n1)CCN(Cc1cccc(Cl)c1)C2=O)N1CCCCC1 +COc1cc2c(cc1OC)C1CC(N)C(c3ccccc3)CN1CC2 +Cc1nn2ncccc2c1-c1ccnc(Nc2ccc(N3CCN(C)CC3)cc2)n1 +N#Cc1nccc(N2CCC(S(=O)(=O)c3cccc(Cl)c3Cl)C2)n1 +CS(=O)(=O)c1cc(C#N)ccc1C1NC(=O)N(c2cncc(Br)c2)C2=C1C(=O)CC2 +CCN(CC)C(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 +O=C(NC1CCC1)c1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +CCc1cc(Nc2cc(=O)n(CCCCCO)c(=O)[nH]2)ccc1C +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CCCCC3C)c2)[nH]1 +NC1CCC(Nc2nccn3c(-c4cccc(NCc5ccsc5)n4)cnc23)CC1 +O=C1CC(C(=O)Nc2cc(-c3cc(F)cc(COCC(F)(F)F)c3)n(-c3ccccc3Cl)n2)CN1 +C=CC(=O)Nc1ccc2ncnc(Cc3ccc(CN(C)C)c(Br)c3)c2c1 +CC(NC(=O)Nc1cc2[nH]nc(C3CCC3)c2cn1)c1ccccn1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n(C)n2C)n1)c1ccccc1 +Cc1nnn(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1NC(=O)OC(C)c1ccccc1 +CCCCS(=O)(=O)N1CC(NC(=O)c2ccc(Cc3cc(C)nc4ccccc34)cc2)C(C(=O)NO)C1 +Cn1c2c(c3ccccc31)CCN(CCCOc1ccccc1)C2 +O=C(CCc1ccccc1)c1ccccc1OCCCCN1CCCCC1 +CC(=O)OC(OC(C)=O)c1ccc2c(c1)COP(=O)(OCC1C=CC(n3cc(C)c(=O)[nH]c3=O)O1)O2 +COc1ccc(C(Cc2ccccc2)NCC(O)Cc2ccc(O)c(NS(C)(=O)=O)c2)cc1O +Cc1cc(C)cc(-c2[nH]c3ccccc3c2CCNCCCCc2cccnc2)c1 +CC(O)c1cccc(-c2cc(OC(=O)NC3CCCCC3)ccc2O)c1 +Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(N)c5)cc(C(F)(F)F)nc34)cn2)cn1 +O=C(Oc1cccc(-c2ccccc2)c1)N1CCc2c([nH]c3ccccc23)C1 +O=C(Nc1ccccc1)OCCc1cc(-c2cncc(OCC3CCN3)c2)on1 +CCN(C)Cc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C(Nc1ccc(C(F)(F)F)cn1)N1CCC(F)(c2ncc(C(O)CO)cc2F)CC1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)c2cncc(F)c21 +O=C1OC2(CCN(CCc3c[nH]c4ccc(F)cc34)CC2)CN1Cc1ccccn1 +CNC(=O)C(NC(=O)c1ccc(-c2cccc(CNC(=O)c3ccnc(C(F)(F)F)n3)c2)o1)C(C)C +CCCCS(=O)(=O)Nc1ccc(C(=O)NC(CC2(C)CCCC2)C(=O)NC2C(=O)COC2CC)cc1 +CS(=O)(=O)N1CCN(c2ccnc(Nc3ncc(-c4cncc(C(=O)NCCN)c4)s3)c2)CC1 +CCCCCCN(C(=O)Nc1ccccc1OC)C(C)c1nc2ccccc2c(=O)n1-c1ccccc1OCC +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 +Nc1ncnc2c1c1ccsc1n2C1OC(CO)C(O)C1O +CCCOc1cncc(C2=CCC3C4CCN5C(=O)CCCCC5(C)C4CCC23C)c1 +CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC(F)F +O=C(NCC(O)C(=O)O)c1ccc(CN(C(=O)Nc2cccc(Cl)c2)c2ccc(C3=CCCCC3)cc2)cc1 +CCN1CCN(Cc2ccc(NC(=O)c3ccc(-c4cc(C)cc(OC)c4C)c4nccnc34)nc2)CC1 +CCN(Cc1ccncc1)C(=O)C(C)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O +O=C(CO)Nc1cncc(-c2cncc(Nc3cccc(Cl)c3)n2)c1 +N=C(NCCCc1c[nH]cn1)NCCC(Cc1ccccc1)c1ccc(F)cc1 +COc1cccc(N2CCN(CCNCCOc3ccccc3)C(Cc3ccccc3)C2)c1 +N#Cc1c(-c2ccccc2)c2ccccc2n(CC2CCCNC2)c1=O +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccoc2)c1 +C=CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +CNS(=O)(=O)Cc1ccc2[nH]cc(CC3CCCN3C)c2c1 +O=C(Oc1ccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)cc1)c1ccccc1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccc(-c4ccccc4)cc3)ccc21 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCCC3)n2)cc1OC(F)F +O=S(=O)(Oc1ccc(Cn2ccnc2)cc1)c1ccc(C(F)(F)F)cc1 +O=C1C2C=CC(C3C2C=CC(=O)C32CO2)C12CO2 +OC(CCN1CCN(c2cccc3cccnc23)CC1)c1csc2ccccc12 +CC(=O)Nc1ccc(Nc2cc(C(C)C)nc3c(-c4ccccc4)c(C)nn23)cc1 +Cc1nnsc1C1=NNC(=O)C1=Cc1cn(C)c2cccc(Cl)c12 +CCOc1ccc2c(c1)C(c1ccc(OC)cc1OCC(C)(C)C(=O)O)N(CC(=O)O)C2c1ccc2c(c1)OCO2 +Cc1cccc(F)c1CN1CC(c2ccc(-c3cnn(CC(N)=O)c3)cc2)C(N(C)C)C1 +CCOC(=O)c1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1 +Fc1ccc(C2COC(c3ccc(C4CNCCO4)cc3)=N2)cc1 +CCC(=CCN1Cc2cc(Cl)cc3nc(S)n(c23)CC1C)CC +COc1ccc(C(=O)NCc2cccc(-c3cccc(CN4CCNCC4)c3)c2)cc1 +Cc1ccc(C(=O)NC2COC2)c(F)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)c3cccc(OC)c3)nc21 +CC1CCC(C)N1C(=O)c1ccncc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1 +Cn1ccc(C2CCNCC2C(=O)N(Cc2cn(Cc3ccncc3)c3cccc(F)c23)C2CC2)cc1=O +Cn1cccc1C(=O)N1CCc2ccc(C(=O)NO)cc2CC1 +O=C(Oc1ccccc1)N1CCN(C2c3ccc(Cl)cc3C=Cc3cccnc32)CC1 +COc1ccc2cc(C(=O)NC(CC(C)C)C(=O)NC(CC3CCNC3=O)C(=O)c3nc4ccccc4s3)[nH]c2c1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3Cl)CC2)cc1 +C=CC(=O)NC1C(NCC(C)C)CC(C(=O)O)=CC1OC(CC)CC +O=C(O)CC1CCC(c2ccc(NC(=O)c3nnc(Nc4ccc(F)c(F)c4)o3)cc2)CC1 +CN(CCCCCN1C(=O)CSC1c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)CCOc1ccc2c(c1)OCO2 +CN(C)CCCCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1 +N#CC1CCCC1Nc1nc(-c2ccccc2)nc2c(=O)[nH]ccc12 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1)CC2 +COc1cc(O)c(C(=O)OC(C)C)c(CCCN2C(=O)C=CC2=O)c1 +Cc1cc(CCNCc2ccc3c(C)cc(N)nc3c2)ccc1C#N 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+NS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccc(F)cc2)cc1 +O=[N+]([O-])c1ncn(CCCCNc2nc(-c3ccccc3)nc3ccccc23)n1 +N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCC=CCNc3ccccc3C(=O)N2)CC1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2cccs2)[nH]c1=O +O=C1OCc2cc(CCN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3)ccc21 +CCOC(=O)c1c(C)n(-c2ccc(Cl)cc2)c2ccc(OC(=O)C=Cc3ccccc3)cc12 +CC#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +COC(=O)C(C)NC(=O)CCC(C)=CCc1c(O)c2c(c(C)c1OC)COC2=O +CN1CCCC(n2c(-c3cccc(C=CC(=O)NO)c3)nc3ccccc32)C1 +COc1ccc2c(c1)C(CC(=O)N1CCN(C(=O)c3ccccc3N3CCC(=O)NC3=O)CC1)CC2=O +OCC1OC(Oc2n[nH]c(C3CC3)c2Cc2ccccc2OCc2ccccc2)C(O)C(O)C1O +CCN(c1cc(-c2ccn(C)n2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +COc1cc2c(cc1OC)C(Cc1ccc(OCCCCCCN3CCCCC3C)cc1)NCC2 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CN(c4ncc(C(=O)O)cn4)C5)cn3)n2)s1 +CN(C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)C1CCN(C(=O)N2CCC(NCCCC3CCCCC3)C2)C1 +O=C(NCc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1cc2cnccc2[nH]1 +O=C(COc1ccccc1)NC(c1ccccc1Cl)c1cc(Br)c2cccnc2c1O +O=C1NCC(=O)N(Cc2ccco2)C1CSCc1ccccc1 +CCC(=O)c1ccc(F)c(C2CC2NC(=O)Nc2ccc(C#N)cn2)c1O +Cc1ccc(C23CC4CC(CC(C(=O)N5CCN(CCO)CC5)(C4)C2)C3)cc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C +O=C1COc2ccc(CCN3CCN(c4cccc5nc(-c6ccccc6)ccc45)CC3)cc2N1 +COc1cc(Cc2cnc(N)nc2N)cc(CC(C)O)c1O +CC1CCCN1CCc1ccc(-c2cccc(S(=O)(=O)N3CCCCC3)c2)cc1 +Oc1ccccc1CNCCCCCCNc1c2c(nc3ccccc13)CCCC2 +N#CC1(c2ccccc2)CCN(Cc2cccc3ccccc23)CC1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ccc(C(F)F)cn3)cs2)CO1 +CC(C)C(Nc1cccc(C(F)(F)F)c1)C(=O)N1CCCCN1C#N +COc1ccc(C(NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)Nc2ccc3c(c2)OCO3)cc1 +O=C(c1cc(-c2cccs2)n[nH]1)N1N=C(c2cccnc2)CC1c1ccccc1O +CN(C)c1nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)cc(C(F)(F)F)n1 +CCOc1ccc2c(c1)C1(C)CCN(CC3CC3)C(C2=O)C1C +Cc1cc(-c2nc3ccccc3[nH]2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 +CC12CCN(C(=O)C3CCC(F)(F)CC3)C(Cc3c(O)cccc31)C2(C)C +N=C(N)NCCC1CCN(C(=O)C(Cc2cccc(C(=N)N)c2)NS(=O)(=O)c2ccc(Oc3ccccc3)cc2)CC1 +O=c1[nH]c2cc(-c3ccncn3)c(-c3ccco3)nc2[nH]1 +CN1CCN2c3c(cccc31)C1CN(CCCC(=O)c3ccccc3)CCC12 +COc1ccccc1C=Cc1nc2c(c(=O)n(C)c(=O)n2C)n1C +CC1(N2CCC(N(c3ccccc3)c3ccccc3)CC2)CCN(C(=O)c2ccccc2)CC1 +O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2C(=O)Nc2ccc(-c3ccc(Cl)cc3)cc2)cn1 +O=C(Nc1ccc(N2CCOCC2)cn1)C1CCC2CN1C(=O)N2OS(=O)(=O)O +COc1cc(C(=O)NCC2(c3ccc(F)cc3)CCC2)ccc1-n1cnc(C)c1 +CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)c(F)cc2n1CC(O)CO +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CC(c4cc(C(F)(F)F)cc(Cl)c4F)=NO2)C3=O)cn1 +CCCCOC(C#CC1CC1)(c1cc(CC)c(C)nc1O)C(F)(F)F +O=C(NC(=S)Nc1ccc(S(=O)(=O)N(Cc2ccncc2)c2ccccc2)cc1)c1ccc2cccnc2c1 +CC(=O)N1CCN(c2cccc(-c3cc(C#N)c4c(N)ncnn34)c2)C(=O)C1(C)C +O=C(Nc1ccc(F)cc1)C(=O)Nc1ccc2c(c1)COC2=O +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)OC(C)C)ncc2c1 +NC(=O)NCCn1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21 +COc1ccn2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cnc2c1 +O=C(c1cccc2ccccc12)N1Cc2ccccc2N(Cc2c[nH]cn2)CC1Cc1ccccc1 +CN(C)CCCN(C(=O)c1cccs1)c1nc2cc3c(cc2s1)OCO3 +O=C(c1cccc(-n2cccn2)c1)N1CCC(F)(F)C(Oc2ccc3ccccc3n2)C1 +FC(F)(F)c1cccc(Nc2n[nH]c3cccnc23)c1 +CS(=O)(=O)Nc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)C=Cc4ccc(Cl)c(Cl)c4)CC3)c2c1 +CCOc1ccc(-c2cccc(NS(C)(=O)=O)c2)cc1-c1ccc2c(N)nc(N)nc2c1 +O=C(O)COc1ccc(C(F)(F)F)cc1-c1ccccc1 +Cc1cccc2c(=O)[nH]c(CCN3CCCC3CO)cc12 +O=c1[nH]c2cc(Cl)c(-n3cccc3)cc2c(=O)n1O +Cc1cc2ccn(C)c2c2c3c(c4c5ccccc5n(CCCO)c4c12)C(=O)NC3=O +O=S(=O)(Nc1ccc(CCNCC(O)c2ccccc2)cc1)c1ccc(Cc2nc(-c3ccc4ncccc4c3)cs2)cc1 +O=C(Nc1cc2ccc(Sc3ccccc3)cc2cn1)C1CC1 +Cc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C2CCOCC2)n1 +NS(=O)(=O)OCC1OC(n2cnc3c(C#Cc4ccccc4)ncnc32)C(O)C1O +CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OC)c2)c2cccnc21 +COc1ccccc1-c1sc(N)nc1-c1ccc(P(=O)(O)O)o1 +O=C(O)COc1cc(CC2CCN(CCc3ccc4c(c3)C(=O)C(O)CO4)CC2)ccc1Br +O=C(C1CN(Cc2ccccc2)CC1c1ccc(Cl)cc1)N1CCN(C2(CNCc3ccccc3)CCCCC2)CC1 +CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc(Cl)cc3)ccc21 +COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cc(C)on4)c4ccccc34)c2cc1OC +NC1=NC(CCc2ccc(NC(c3ccc(Br)cn3)C(F)(F)F)cc2)CO1 +Cc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C(O)C(C)C)n1 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+CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)cc(-c3ccc(F)cc3)c2C)cc1 +O=C(c1ccc(-c2cn3c4nc(ncc24)NCCCCCCCC(O)CCCC3)cc1)N1CCOCC1 +N=C(N)NCCCCCCCCCNc1c2c(nc3ccccc13)CCCC2 +CC(C)(C)c1cc(NC(=O)C(=O)c2cccc3ccccc23)n(-c2ccc(OCCC(N)=O)cc2)n1 +COC1CN(c2nc(-c3cc(C)ccc3OCc3ccc4c(c3C)CCN(C3CCOCC3)C4=O)cs2)CCC1C(=O)O +CCc1oc2ccccc2c1C1CCN(CCc2ccccc2)CC1 +Cc1csc[n+]1CCCCCCCCCCCC[n+]1cscc1C +Cn1ncc2cc3c(cc21)ncc1c(=O)n(-c2ccc(Cl)cc2)[nH]c13 +CCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2cc(F)ccc21 +Nc1nc(-c2ccccc2)c2c(n1)-c1cc(CNN3CCCCC3)ccc1C2=O +Cn1cc(-c2ccccc2)nc1SCc1cn2c(C(F)(F)F)cccc2n1 +COc1cc(N2CCN(C)CC2)ccc1Nc1nc(N)n(C(=O)NCc2ccccc2S(=O)(=O)C(C)C)n1 +Nc1ccc(NCCc2ccc(OCCCN3CCCCC3)cc2)nc1 +Nc1ncc2cccc(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2n1 +O=C(c1ccccc1)N1CC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)C1 +CC1C(=O)N(Cc2ccc(F)c(F)c2)c2c(C=CC(=O)NS(=O)(=O)c3cccc(Cl)c3)cccc21 +NS(=O)(=O)c1ccc(C(=O)NC(C(=O)NCC(=O)NCC(=O)OCc2ccccc2)c2ccccc2)cc1 +Cc1cc(Nc2nc(Sc3ccc(Cl)c(Cl)c3)nc3ccccc23)n[nH]1 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+Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCC(NC(=O)C=CCN2CCOCC2)CC1 +COc1cc(N(CC2CC2)c2ccc3c4c(cccc24)CC3)cnc1C(=O)C1CC1C(=O)O +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)cc1OCCCNCC(O)c1ccc(O)c(CO)c1 +Nc1ncnc2c1ncn2C1OC(CSC2CNC(C(=O)O)C2)C(O)C1O +O=C(NCc1cn(-c2ccc(F)cc2)nn1)C(Cc1cscn1)NC(=O)C1OC1C(=O)O +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCCCN(C)C +COCc1c(-c2cc3cc(OC)cc(OC)c3s2)c2c(N)ncnn2c1CN1CCNC(=O)C1 +O=C1C(NCCN2CCCC2)=CC2=NCCc3c[nH]c1c32 +COc1ccc(-c2n[se]nc2-c2ccc3c(c2)OCO3)cc1O +CC(C)(C)c1ccc(-n2c(C(=O)O)c(Oc3cccc(C(F)(F)F)c3)c3ccccc32)cc1 +CC(C)(NC(=O)c1nn(-c2ccc(F)cc2F)c2c1CC1CC21)c1cccnc1 +Cn1cnc2cc(-c3ccc4c(c3)CC(=O)N4)nc(N3CCC(CO)C3)c2c1=O +Oc1ccc2c(c1)C1(CCc3ccccc3)CCN(CCc3ccc(C(F)(F)F)cc3)CC1O2 +Cn1cc(-c2ccc(N3CCC(n4ncc5ccc(C(F)(F)F)cc54)CC3)nn2)cn1 +N#Cc1cccc(C(=O)Nc2ccc(CC(NC(=O)C3CCC(=O)N3Cc3ccccc3)C(=O)O)cc2)c1 +Cn1nc(C(C)(C)C)c(Cl)c1-c1nc2cc(-c3ccccc3C(F)(F)F)nc(N3CCOCC3)c2[nH]1 +N#Cc1cccc(-c2ccc(C3(OCC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)CCN(C4CCCC4)CC3)cc2)c1 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+O=C(NNc1cccc2ncccc12)C1(c2cccc(F)c2)CCCCC1 +COc1cc2c(cc1OC)C1C3Cc4cc(OC)c(OC)cc4C(COC(=O)c4cccs4)N3C(C#N)C(C2)N1C +Cc1ncc(C)c(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)n1 +COc1cccc(N2CCN(CCCN3C(=O)CCc4c(Cl)cccc43)CC2)c1 +COc1cc2ncnc(N3CCC(Oc4cc5ccccc5cn4)C3)c2cc1OC +CSCCC(NC(=O)c1cccc(CN(Cc2ccccc2)Cc2c[nH]cn2)c1)C(=O)O +CCS(=O)(=O)CCc1ccc(-c2nnc(-c3ccccc3C(F)(F)F)n2C)c(C)c1 +CC(NC(=O)C(O)C(N)CCc1ccccc1)c1cccc2ccccc12 +CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ncccc4c3cc12 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc4cc(-c5cccc(C(F)(F)F)c5)ccc4n3)C12 +Oc1ccc(-c2cncc(-c3cc4ccc(O)cc4[nH]3)c2)cc1 +COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2s1 +CC(C)CC(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)N(C)C +N#CC1CCCN(c2cccnc2Oc2ccc(Nc3ccccn3)cc2)C1 +O=C(O)c1ccc(Cl)cc1-c1ccc2c(c1)OCC(Cc1ccc(C(F)(F)F)cc1)C2O +CN1C(=O)c2c(nn(Cc3ccc(-c4cc(F)ccn4)cc3)c2Nc2ccccc2)N2C1=NC1CCCC12 +Fc1ccc(-c2[nH]c(-c3ccc(Br)cc3)nc2-c2ccncc2)cc1 +COc1ccc(N2CCC(NC(c3cccnc3)c3ccc(Cl)cc3F)CC2)cc1F +N=C(N)N1CCCC(CNC(=O)CNS(=O)(=O)c2ccc3ccccc3c2)C1 +O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cc2ccccc2o1 +O=C(NCCNCCO)c1cccc2ccc(-c3ccccc3)nc12 +CC1(c2cccc(O)c2)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O +CC(C(O)c1ccccc1)N(C)C(S)=Nc1ccc(Oc2ccccc2)cc1 +COC(=O)c1ccc(SCc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 +O=C(CCN1CCC(n2ccnc2)CC1)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1 +CCC(C)C1(NC(C)=O)CCN(C(C)C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(O)CN2)C1=O +O=C(NO)c1ccccc1S(=O)(=O)N1CCC(Cc2ccccc2)CC1 +CN(c1ncccc1CNc1c(C(F)(F)F)cnc2[nH]c(-c3ccc(F)cc3)nc12)S(C)(=O)=O +Cn1c(=O)n(C2COC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 +c1ccc(C2CCc3cc(Oc4ncc(CNCC5CC5)s4)ccc3O2)cc1 +CC(C)(CO)n1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +CN(C)C(=O)c1cccc(N=c2c(O)c(O)c2=Nc2ccccc2)c1O +O=C(Nc1nc(CN2CCC(C(=O)NC3CCCC3)CC2)cs1)c1ccc(Cl)cc1 +O=C(Nc1nnc(SCc2ccccc2)s1)c1ccc(Cl)cc1 +Nc1cccc(CN2C(=O)N(Cc3ccc4[nH]ncc4c3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)c1 +Oc1ccc2c3c1OC1c4nc5ccccc5cc4CC4(O)C(C2)N(CC(F)F)CCC314 +COc1cc[nH]c1C=C1C(=O)Nc2ccc([N+](=O)[O-])c(N3CCC(N)C3)c21 +NC(=O)c1ccc(N2CCC(NC(=O)c3ccc(F)c(F)c3)C2)c2cncnc12 +CCOC(=O)c1cc(C(=O)OC)c(C)nc1N1CCC(NC2CCCCC2O)CC1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccccc3C)NC(=O)NC1=O)C2 +CCc1nc2c(c(OCC(F)(F)F)c(C(=O)NC3CCN(C(=O)CO)CC3)n2C)c(=O)n1CC(=O)c1ccccc1 +NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1Br +CC(C)CC(NC(=O)C(Cc1cccnc1)NC(=O)N1CCOCC1)B(O)O +C=CCN(C(=O)NCc1ccc(F)cc1F)C1CCN(CC2CN(C(=O)C3CCCC3)CC2(O)c2ccccc2)CC1 +CC(C)n1nc(-c2cc(-c3cccs3)on2)c(C(N)=O)c1N +N#Cc1cccc(Cn2c(CC3(C(=O)O)CCCC3)nc3cc(OCc4ccc5ccccc5n4)ccc32)c1 +O=C(Nc1ccc(CCNc2ncnc3oc(-c4ccccc4)c(-c4ccccc4)c23)cc1)c1ccccc1 +Cn1c(Cc2nc3c(F)c(F)cc(F)c3[nH]2)nc2ccc(C(=O)NC(CP(=O)(O)O)C(=O)O)cc21 +CC1COCCN1C(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nccnc12 +COc1c(OC2CCC2)ccc2c1CCN(Cc1ccc(C(C)NC(C)=O)cc1)C2 +Cc1cc(C)[n+](-c2ccc(S(=O)(=O)Nc3nnc(S(N)(=O)=O)s3)cc2)c(C)c1C +O=C(C(Nc1ccccc1F)c1ccc(C(F)(F)F)cc1)N1CCCC1c1cccnc1 +N#Cc1cc(Oc2cncnc2)cc(C(=O)Nc2ccc(F)cn2)c1 +O=C(O)CC(NC(=O)CN1CCC(CCc2ccc3c(n2)NCCC3)C1=O)c1cccc(F)c1 +O=C(CCn1c2c(c(=O)[nH]c1=O)COCC2)NCC(=O)N1CCN(c2ncccn2)CC1 +N#Cc1cc(C(=O)Nc2cc(-c3ccccc3)nn2-c2ccccc2Cl)ccc1-c1ccc(F)cc1 +O=C(c1ccccc1)N(O)CCC(c1ccc(Cl)c(Cl)c1)P(=O)(O)O +CCC(Nc1cc(CNCCC(=O)O)c(Cl)cn1)c1ccc(Cl)c(C)c1 +O=CC(CC(=O)O)NC(=O)C1CCCN2C(=O)CCC(NC(=O)OCc3ccccc3)C(=O)N12 +COC(=O)C(C)(C)Cn1c(=O)[nH]c(=Nc2ccc(Cl)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O +N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)NC(Cc3ccccc3F)C(=O)O)c(Cl)c2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(c2ccc(F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1cc(F)cc(C(F)(F)F)c1 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(c5nncs5)CC4)ncn3)c2c1 +COc1ccccc1N1CCN(CCCCNC(=O)C=Cc2ccc(-c3ccccc3)cc2)CC1 +O=C(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1cc2cc(O)ccc2n1Cc1cccc(C(F)(F)F)c1 +CCCN1C2CCC1C(C(=O)OC)C(c1ccc(F)cc1)C2 +O=C(NC(Cc1ccccc1)C(=O)NC(C=CS(=O)(=O)c1ccccc1)CCc1ccccc1)c1cc(F)cc(F)c1 +O=C(Nc1ccc(N2CCN(C(=O)C3CCC(C(=O)O)CC3)CC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F 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+NC(=O)C(CCc1ccccc1)NC(=O)C(N)Cc1ccccc1 +CC(C)(C)c1ccc(-c2cc(=O)cc(N3CCOCC3)o2)cc1 +O=C(c1nc2nccc(C(=O)NC3CCCNC3)c2[nH]1)c1cccs1 +O=c1[nH]c(-c2cccs2)nc2cn(-c3ccccc3)nc12 +Brc1ccc(C2=NN(c3ccccc3)C(c3cccc4ccccc34)C2)cc1 +Cn1cc(-c2cc(C(N)=O)nc3cc(CN4CCCCC4CF)ccc23)cn1 +NCCC(O)CNC1CC(N)C2(CCC(O)C(O)CO2)C(O)C1O +O=C(O)C(=O)CC(=O)c1cccc(Cc2cccc(F)c2)c1 +CC(=N)NCCNc1c2c(c(NCCNC(C)=N)c3sccc13)C(=O)c1ccccc1C2=O +COCCNC(=O)c1ccc(Nc2ncc3cc(-c4ccncc4)ccc3n2)cc1C +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2CC(=O)NCC2CC2)cc1 +CNc1nc2cc(-c3cccc(CCNC(N)=O)c3)sc2n2c(C)cnc12 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2cc(F)cc3c2OCOC3)[nH]c1=O +CCCCN(CCC)c1nc(C)nc2c(-c3c(C)cc(N(C)C)nc3C)c(C)nn12 +CC(C(=O)NCc1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(Br)c1 +O=C(Nc1ccc(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cc1)NN1CCCCC1 +NCCCCC(NC(=O)C1CC1)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 +COc1ccccc1C(=O)N1CCCN(CC(=O)NC2CC(=O)OC2O)C(=O)C(NC(=O)c2ccc3ccccc3c2)C1 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+CNC(=O)c1cccc(Nc2ncnc(N3CCC(c4csc(-c5ccccc5)n4)CC3)n2)c1 +Cc1cc(-c2cn(CC3CNC3)c(C3CCN(c4ncnc(N)c4OCC(F)(F)F)CC3)n2)ccc1F +Cc1c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)ccc2cc(C#N)ccc12 +COc1cc(OC)cc(-c2nccnc2C2CN(C(=O)c3nc4ccccc4[nH]3)C2)c1 +CN1CCC=C(c2nsnc2OCCCCCCCCCCCCOc2nsnc2C2=CCCN(C)C2)C1 +CC(=O)NCCc1c(Cc2ccccc2)oc2ccc(O)cc12 +CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)cc1Cl +CCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ncnc(NCC5CC5)c4Cl)C3)cc2)s1 +O=C(CCCCCCNC(=O)N1Cc2ccccc2C1)NCCCc1ccccc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(C(=O)OCc2ccncc2)CC1 +Cc1cc(COc2ccc(S(=O)(=O)N3CCCC(C)(C(=O)NO)C3)cc2)c2c(n1)CCCC2 +O=C(Nc1cccc(F)c1)Nc1cc(C(=O)NCCN2CCCC2)ccc1Oc1ccc(F)c(F)c1 +O=P(O)(O)OC1C(O)C(OP(=O)(O)O)C(F)(F)C(O)C1OP(=O)(O)O +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)n(-c2ccccc2N)n1 +O=C(O)c1ccc(N2CCC(CN3CCC(Oc4ccc(Cl)c(Cl)c4)CC3)CC2)cc1 +O=C(O)CC(NC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1)c1ccccc1 +CN1C2CCC1CC(OC(=O)c1cn(CC(F)(F)F)c3ccccc13)C2 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3cccc(Cl)c3)cc2)C(=O)C(C)C)c1 +CCCCC(C=O)NC(=O)OC(C)(C)Cc1ccccc1Cl +Oc1cccc(F)c1-n1nc(OC2CCNCC2)c2c1CCCC2 +CC(OCc1cc(Cl)cc(-c2cc(NC(=O)C3CNC(=O)N3)nn2-c2ccc(F)cc2)c1)C(F)(F)F +COC(=O)C1=C(Nc2ccc(C)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O +CC1CN(C(=O)C(C)(O)C(F)(F)F)CCN1S(=O)(=O)c1ccc(C(C)(C)C)cc1 +Cc1sc(NC(=O)C2CCCCC2C(=O)O)c(-c2nc(C3CC3)no2)c1C +COc1ccc(COc2ccc(Cn3c(N)nc4cc(-c5cnn(C)c5)cnc43)cc2OC)cn1 +CN(CC(=O)NC(CCCCN)C(=O)C(=O)Nc1ccccc1)C(=O)c1ccccc1Sc1ccccc1C#N +COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCSCC5)cn4)ccc23)c(Cl)cc1Cl +NC1CCN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc4[nH]ccc4n3)c(F)c2)CC1 +Brc1cnc(Nc2cccc3ccccc23)nc1Nc1cc(C2CC2)[nH]n1 +Cc1cc(C)cc(COC2C3CCN(CC3)C2C(Cc2ccccc2)c2ccccc2)c1 +Cc1cc(NC(=O)C(=O)O)cc(C)c1Oc1cccc(-c2ccccc2)c1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2cc(-c3cc4ccccc4o3)ccc2CC1C(=O)O +COc1cc(CC(=O)NCc2ccc(C(C)(C)C)cc2)ccc1O +Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4CCC(C(=O)N5CCC(F)(F)C5)C4)cc3)nn3cccc23)n[nH]1 +O=C1CC2OC(Cc3ccccc3)C(OCc3ccccc3)C2O1 +Cn1ncc2cc(-c3ccc4oc(NC5CCCCC5)nc4c3)ccc21 +O=S(=O)(c1cccnc1)N(Cc1ccc(C(F)(F)F)c(F)c1)c1sc2ccccc2c1Br +O=CN(O)C(CCc1ccc(C(=O)O)cc1)CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 +O=C(NCc1ccccc1)Oc1ccc2c(c1)C13CCCCC1C(C2)N(CC1CC1)CC3 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(C(=O)NC2CC2)cc1 +O=C(CSc1snnc1-c1ccc(Br)cc1Br)Nc1ccccc1Cl +CCOC(=O)c1c(-c2cccc(OC(F)(F)F)c2)[nH]c2cc(OC)c(F)cc2c1=O +Cc1cc(COc2ccc(S(=O)(=O)CC(CC3CCC(=NO)CC3)N(O)C=O)cc2)c2ccccc2n1 +COc1cc2c(N3CCN(C(S)=NCc4ccc(C(F)(F)F)nc4)CC3)ncnc2cc1OCCCN1CCCCC1 +CC(=O)Nc1ccc2cccc(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2n1 +NC1CC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(Cc2ccccc2)C(=O)NC(Cc2ccccc2)CNC1=O +N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ncccn5)cc4s3)o2)CC1 +CCc1cnc(N2CCC(n3nnc4cc(-c5ccc(S(C)(=O)=O)cc5)ccc43)CC2)nc1 +CC(C)c1ccccc1NC(=O)N1CCOc2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc21 +COc1cc(C(C)C#Cc2c(C)nc(N)nc2N)ccc1-c1ccccc1C +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1OC(=O)NC +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4ncccc4n3)cc2)no1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3cccc(OC)c3OC)ncc2C(F)(F)F)c1 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+O=C(Nc1n[nH]c2nc(-c3cccs3)c(Br)cc12)C1CCCC1 +CN(C)CCNc1cc(Nc2cc(C3CC3)[nH]n2)nc(-c2ccccc2)n1 +CC(C)Oc1cc(N2CCC(Oc3ccc(C(C)NC(=O)C(C)F)cc3)C2)ccn1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CCC(O)CC4)c4ccccc4n3)c(C)c12 +Cc1cc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)c(CN4CCOCC4)n2CCO3)no1 +O=CC1CCCN1C(=O)C1Cc2ccccc2N1C(=O)OCc1ccccc1 +CC(C)N(c1ccccc1)S(=O)(=O)c1ccc(O)cc1 +CC1CN(C(C)C)C(=O)c2cccc(NC(=O)c3cccnc3)c2OC1CN(C)Cc1ccc(Oc2ccccc2)cc1 +COc1cc(OC)cc(C(C#N)=Cc2ccc(C)cc2)c1 +CN(C)CCCCCNc1c(Br)cccc1Nc1ncnc2ccncc12 +CCCCOc1c(O)ccc2c1C13CCN(CC4CC4)C(C2)C1(OC)CCC(=O)C3 +COCCCCNC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NCC(c1ccc(Cl)c(Cl)c1)N1CCC(N(CCO)CCO)CC1 +CC(C)c1ccccc1OCC(O)CN1CCC(CN2C(=O)CCCC2=O)CC1 +O=C(C=Cc1ccc(F)cc1)Nc1cc(-c2ccccc2)[nH]n1 +COc1ccc(N2CCN(c3nc(Nc4cc(C(C)(C)C)ccc4C)cc(S(C)(=O)=O)n3)CC2(C)C)cc1 +CCOC(O)=C1C(COCCNc2n[nH]c(N)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1 +NC(=O)Cc1ccccc1CCc1nc(Nc2ccc(C3CCNC3)cc2)ncc1C(F)(F)F 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+COc1cc2nc(-c3nccs3)n(-c3cc4nc(N)nc(N)c4cc3Cl)c2cc1OC +Cc1cccc(C(=O)N2CCC(N3CCC(n4c(=O)[nH]c5ccccc54)CC3)CC2)c1 +c1ccc(C(OCCCc2c[nH]cn2)c2cccnc2)cc1 +CCc1nc(N)nc(N)c1-c1ccc2c(c1)N(CCCOC)C(=O)C(C)(C)O2 +Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC(C)C)cn1 +CCCOc1cccc(CNC(=O)Nc2nc(-c3ccncc3)cs2)c1 +COC1CN(c2cccc(-c3cc(C)ccc3OCc3ccc4c(c3)CCN(C3CCOCC3)C4)n2)CCC1C(=O)O +COc1cc(C#CC(=O)OCCCCN(C)CCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC +CC(=O)C1CCC2C3CCC4CC(O)C(N5CCOC(C)C5)CC4(C)C3CCC12C +NS(=O)(=O)NCC1OC(n2cnc3c(NCc4cccc5ccccc45)ncnc32)C(O)C1O +CCC(=O)NCC1=Cc2ccccc2C(c2ccccc2)C1 +Cc1nnc(N2C(=O)c3cccc4c([N+](=O)[O-])ccc(c34)C2=O)s1 +O=S(=O)(Nc1ccc(F)c(C#Cc2cnc3[nH]ccc3c2)c1F)c1cccc(Cl)c1 +CC(Oc1ncccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(F)c12)C(F)(F)F +O=C(NNCc1ccc(Cl)cc1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 +CC(C)=CCOc1cc(Oc2ccc(S(=O)(=O)N3CCC(F)C3)cc2)cc(C(=O)Nc2ncc(F)s2)c1 +CC1CC2CC(C1)CC(N1C3CCCC1CC(n1c(=O)c(C(=O)O)nc4ccccc41)C3)C2 +O=C(NCc1ccc(F)c(F)c1)c1c(C2CCCC2)n(Cc2ccccn2)c2ccc(O)cc12 +CC#Cc1cc(C2(c3ccc(OC(F)F)cc3)N=C(N)N(C)C2=O)ccc1F +Cc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1 +COc1ccc(C=CCN2CCN(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 +Cc1cc(-c2nc3cc(C(=N)N)ccc3[nH]2)c(O)c(-c2cc(CNC(N)=O)ccc2O)c1 +CCOc1cc(C2C(C(=O)OC)=CNC=C2C(=O)OC)cc(Br)c1OCC +Cc1[nH]c(C)c(-c2ccc(-c3ccc(Cl)cc3)cc2)c(=O)c1Cl +COc1cc2c(cc1OC)C(=O)C(=Cc1ccc(N3CCN(c4ccccn4)CC3)cc1)C2 +Cc1c(Cl)cccc1-c1cccc(COc2ccc(C(CC(=O)O)c3nccn3C)cc2)c1 +COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OCCCCCCC(=O)O +CSCCC(NC(=O)C1CC(Oc2ccc(-c3ccccc3)cc2)CN1CC=CC(N)CS)C(=O)O +COc1ccc(CC(=O)Nc2cc(-n3nc(C)cc3C)nc(-c3ccc(C)o3)n2)cc1 +CNc1nc(Nc2cc3c(cc2OC)N(C)C(=O)C(C)(C)O3)ncc1C(F)(F)F +CC1CN(C(=O)OC(C)(C)C#N)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)c3nccc(N)n3)cc2F)cn1 +CCCOc1cc2c(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)ncnc2cc1OC +O=S(=O)(Nc1ncc(F)s1)c1ccc2c(-c3ccc(C(F)(F)F)cc3C3=CCNCC3)cccc2c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(Cl)s4)nc23)N1 +CC(C)(O)C1CCCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C 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+O=C1CC(CN2CCN(c3ccccc3)CC2)Cc2occc21 +COCc1ccc2c3nc(N4CCCC(N)C4)n(Cc4ccccc4Cl)c3c(=O)n(C)c2c1 +Cc1cccc2cc(C(C)Nc3ncnc4[nH]nc(Cl)c34)n(-c3ccccc3)c(=O)c12 +CCN1C(=O)c2nc(-c3ccc(-c4ccc(F)cc4F)nc3)n(Cc3ccc(F)c(F)c3)c2N2CC(C)(C)N=C12 +Cc1cccc(-c2[nH]c(CNc3cccc(C(N)=O)c3)nc2-c2ccc3nccnc3c2)n1 +COc1cc2c(cc1OC)C(CC(O)c1ccc(Cl)cc1)N(C)CC2 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCc1cccn1C +Cc1ccccc1NC(=O)C1CCCN1S(=O)(=O)c1ccccc1C(F)(F)F +CC1C2Cc3ccccc3C1(C)CCN2C(=O)C1COc2ccccc2O1 +Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1cccc(CNC(=O)CO)c1 +COc1cccc(OCC(=O)NC(Cc2ccccc2)C(O)C(=O)N2CSC(C)(C)C2C(=O)NC2c3ccccc3CC2O)c1 +CN(CCOc1cccc(NC2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)c1)c1ccnc(F)c1 +CC1CCN(C(=O)C(CCCN=C(N)N)NS(=O)(=O)c2cccc3c2CCCC3)C(C(=O)O)C1 +Cc1nc(NC(=O)NC(c2ccccc2)C(C)(C)O)cc2[nH]nc(OCCO)c12 +Cc1ccc(NC(=O)C=CC(=O)N2CC(=Cc3ccccc3)C(=O)C(=Cc3ccccc3)C2)cc1 +O=C(NCc1ccc(N2CCOCC2)cc1)n1sc2ccccc2c1=O +Cc1cc2nc(C)c(CN3CCN(c4ccccn4)CC3)n2c(C)n1 +CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccc(C(=O)O)cc2)nc1C=CC(=O)O +Cc1ccc(Cn2c(C)c(C)n3c4c(=O)[nH]c(=O)n(C)c4nc23)cc1 +COc1ccc(F)c(CC2CCN(CCc3ccccc3)CC2)c1 +CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)C1 +CC(C)CS(=O)(=O)c1ccc(C=NNC(=O)c2ccc(O)c(Cl)c2)c2ccccc12 +O=c1[nH]cccc1-c1cccn2nc(Nc3ccc4ncccc4c3)nc12 +Cc1c(C(=O)NCC(O)CN2CCN(c3cccc(Cl)c3Cl)CC2)nc(-c2ccccc2)n1-c1ccccc1 +CCc1cccc(C2=CCN(C(=O)C3NCC4(CC4)CC3C(=O)NO)CC2)c1 +COc1ccc(-c2cc3nc(C)c(C)c(N4CCN(C(=O)c5ccco5)CC4)n3n2)cc1 +CN=C(S)C1=CC(C)(C(F)(F)F)Oc2ccc([N+](=O)[O-])cc21 +COc1cc([N+](=O)[O-])ccc1NC(=O)Nn1cnnc1 +O=C(CCC1CCN(Cc2ccccc2)CC1)c1cc2c3c(c1)CC(=O)N3CCC2 +CCOCC1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +CCN1CCC(c2ccn3c(-c4ccnc(N)n4)c(-c4ccc(F)cc4)nc3c2)CC1 +O=C1NCC(=O)N(Cc2ccc(Cl)cc2)C1Cc1c[nH]c2ccccc12 +N#Cc1ccc(N2CCN(C(=O)c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3CC(N)=O)CC2)nc1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(COC(=O)C(N)CO)cccc4n3)c(C)c12 +COc1cc(OCc2cccc(-c3nc(CO)c(C)s3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(O)CCc1ccccc1-c1cccc(-c2ccccc2OCc2ccccc2)c1 +Oc1cc2c(cc1O)C(Cc1cc(I)c(I)c(I)c1)NCC2 +COc1ccc(N2C(=O)c3c(Cl)cccc3C2C)cc1OCCN1CCC(C)CC1 +COc1cc(F)cc(-c2ccc(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)c(OC)c2)c1 +CCN1C(C(=O)NC(Cc2ccccc2)C(=O)C(=O)NC(C)C)Cc2cc3c(cc2S1(=O)=O)OCCO3 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(N)c2)n1C +O=S(=O)(Nc1ncns1)c1ccc(Oc2ccc(-c3ccccc3)cc2)c(Cl)c1 +NS(=O)(=O)OCC1CC(Nc2cc(NC3CCc4ccccc43)ncn2)CC1O +CCCCCN(CCCCC)C(=O)C(CCC(=O)O)NC(=O)c1cc2ccccc2[nH]1 +COCCOc1n[nH]c2cc(NC(=O)NCC(C)c3ccccc3)ncc12 +CC(Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2cnc(C(F)(F)F)cn2)CC1)C(F)(F)F +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C(C)CNCc1ccccc1C(C)C +CN(C)CCCCN(Cc1nc2ccccc2[nH]1)C1CCCc2cccnc21 +CS(=O)(=O)N(Cc1ccc2ccc(C(=N)N)cc2c1)c1ccc(-c2ccccc2S(N)(=O)=O)cc1 +CC(=O)Nc1cnc2c(ccn2-c2cc(NC(C)C)c(C(=O)NCC(F)C(C)(C)O)cn2)c1 +CCCOc1ccc(N2CC(c3ccc(CC(C)NC(C)=O)cc3)C2)c(OC)c1 +Cc1cc(C)[n+](CC(=O)Nc2ccc(S(N)(=O)=O)cc2Br)c(C)c1 +O=C(CN1C(=O)C2C3CCC(C3)C2C1=O)N1CCCC(c2ncncc2-c2ccncc2)C1 +O=C(NO)C(Cc1cccc(Oc2ccccc2)c1)C(=O)N1CCc2ccccc2C1 +Cc1c(N(Cc2ccc(F)c(Cl)c2)S(=O)(=O)c2ccccc2)nc2ccc(Cl)cn12 +CC(NC(=O)N(C)C)c1ccc(OC2CN(c3ccc(OC4CC4)cc3)C2)cc1 +Cc1cc2oc(Cc3cccc(Cl)c3)nc2c(NCC(F)(F)c2ccccn2)n1 +COc1ccccc1-c1cc2c(NC3C4CC5CC3CC(O)(C5)C4)c(C(N)=O)cnn2c1 +Cc1c(C(=O)NC(=O)CC(C)(C)C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)CC(=O)Nc1cc(C(F)(F)F)ccc1NC(=O)OC(C)(C)C +CCOC(=O)c1c(NCCN(C)C)n(-c2ccccc2)c(=S)n(-c2ccccc2)c1=O +NC(=O)c1cc(-c2ccncc2)[nH]c1-c1cccc(F)c1 +Cc1nc2cc(-n3ncc(C(=O)c4cc5cc(-n6ccnc6)ccc5[nH]4)c3N)ccc2[nH]1 +CCCN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCCC4)n3)cc2)C1=O +O=[N+]([O-])C=Cc1cccc(OCc2ccc(F)cc2)c1 +CC(C)(C)CN1CCC(c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)CC1 +CC1CN(c2ccc3ccccc3n2)CCN1CCCN1C(=O)c2ccccc2C1=O +CCN(CC)CCOc1ccc(-c2cc(C(=O)Nc3cccnc3)c(NC(N)=O)s2)cc1 +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(OC)cc3Cl)ccnc21 +O=C(c1ccc2c(c1)C(O)(C(F)(F)F)c1ccccc1-2)c1cccs1 +CN1CCN(c2ccccc2NC(=O)c2ccc([N+](=O)[O-])o2)CC1 +CCCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)CN(C)CC3)cc1 +N#Cc1cccc(C(=O)N2CCCCC2CCOc2ccc(Cl)c(Cl)c2)c1 +CCOCC(CC(C)C)NC(=O)C1CNCC(C(=O)N(c2cc3c(cc2F)OC(C)(C)C(=O)N3CCCOC)C2CC2)C1 +COCC(NC(=O)Nc1cc2[nH]nc(-c3ccc4c(c3)nnn4C)c2cn1)c1ccc(F)cc1 +CC1CN(c2cncnc2)Cc2cc(C(=O)Nc3cc(CN(C)C)cc(C(F)(F)F)c3)ccc21 +CC1(O)C(O)C(CO)OC1n1cnc2c(NCc3ccccc3)ncnc21 +CCCCc1nn(C(C)CC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(NCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2)c1c[nH]c2ccccc12 +NC(=O)c1cc(-c2ccncc2)cc(-c2ccc(S(N)(=O)=O)cc2)c1N +CC(C)(NC(=O)c1nn(-c2ccc(F)cc2F)c2c1CC1CC21)c1ccncc1 +O=C(Nc1nc2ccccc2n2cncc12)c1c(Cl)cccc1Cl +CC(=O)c1cccc(-c2cc(N3CC(N)C(c4cc(F)c(F)cc4F)C3)ncn2)c1 +Cc1ccc(F)c(Nc2ccc(-c3cnc4ccc(NC5CCC(N)CC5)nn34)cc2)n1 +O=C(OCCF)C1C2CCC(CC1c1cccc(C=CI)c1)N2 +O=C(C[S+]([O-])C(c1ccc(F)cc1)c1ccc(F)cc1)N1CCN(CCCc2ccccc2)CC1 +COc1cc(N2Cc3ccc(-c4ccc(C)c(C)c4)nc3C2=O)ccc1OCCN1CCCC1 +CC(C(O)c1ccc2c(c1)CC(=O)N2)N1CCC(Cc2ccccc2)CC1 +O=C(CSC(=S)NN1CCN(c2ccccc2)CC1)NCc1ccc2c(c1)OCO2 +CC(=NOC1CCNC1)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +NC1=NC(CF)(c2cc(C#Cc3ccc4[nH]ccc4c3)ccc2F)CC(C(F)(F)F)O1 +Cn1cc(NC(=O)c2cc(NC(=O)c3ccc(C=Cc4nc5ccccc5o4)cc3)cn2C)cc1C(=O)NCCN1CCOCC1 +C#CCCCC#Cc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +Cn1nc2c(c1Cc1cccc(C(F)(F)F)c1)CC(N)C(=O)N2O +CC(C)c1nc2c(c(Nc3ccc(Cl)c(Cl)c3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +O=C(NC1=NN(c2ccccc2)C(=O)C1)Oc1ccccc1 +O=C(Nc1c(Cl)cncc1Cl)C(=O)c1cc(Cc2ccc(O)cc2)n2ccccc12 +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1Br)c1ccc2ccnc(N)c2c1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2cc(Cl)ccc2Cl)C1 +CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(-c3ccccc3F)cc(N3CCOCC3)nn12 +O=c1cc(-c2cccc([N+](=O)[O-])c2)oc2ccc(Br)cc12 +CC1CCN(CCCOc2ccc3c(c2)N(Cc2ccc(F)cc2)C(=O)CC3)CC1 +N#CC(CC(N)=O)NC(=O)C1CCCN1C(=O)OCc1ccc(-c2cc(F)cc(F)c2)cc1 +O=S(=O)(Nc1ccc2c(C=Cc3ccc4ccc(Cl)cc4n3)cccc2c1)C(F)(F)F +CC(C)CNc1nc(C#CC2CCCCC2)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +Cc1cc(C(=O)O)c2[nH]c(-c3c(F)c(F)c(-c4cccc(OCc5ccccc5)c4)c(F)c3F)nc2c1 +O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1cc(Cl)ccn1 +O=C1NC(=O)C(=Cc2ccc(OCCNc3nc4ccccc4s3)cc2)S1 +Cn1cc(NC(=O)c2csc3ncc(NC4CCCCC4N)nc23)c(C(F)F)n1 +CCc1nc(-c2cccc(Cl)c2)c(-c2ccnc(NC(=O)c3ccccc3)c2)s1 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2noc(COc3ccccc3O)n2)cc1 +NC(CC(CP(=O)(O)O)=NOCc1ccccc1)C(=O)O +Cc1nc(NC2CCSCC2)nc(-n2ccnc2C)c1[N+](=O)[O-] +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2nc3ccccc3n2C)c1 +Cc1ccc(C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCCC3)nc12 +CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1ccc(F)cn1 +Cc1cc(-c2cccc(O)c2F)cc2nnc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nc12 +CCCCCCn1ccnc1C=CC(=O)C=Cc1nccn1CCCCCC +CN(C)C1CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncc(F)c2)CC1O +Cc1nc(Cl)c(Sc2ccc(Cl)cc2)c(N2CCN(C)CC2)n1 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(OCCCN3CCCC3)cc2)nc1 +COC(=O)C(NP(=O)(OCC1OC(C)(C)OC1C(=O)NO)Oc1ccc(C)cc1)C(C)C +COc1ccc2c(c1CN1CCNCC1C)OC(=Cc1n[nH]c3ncccc13)C2=O +CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3ccncc3)c3ccccc23)CC1 +COc1cccc(N2CCN(CCNCCc3ccccc3)C(Cc3ccc(O)cc3)C2)c1 +CCc1ncnc(N2CCC(CC(C)(C)O)CC2)c1C#Cc1ccc(N)nc1 +COc1ccc(-n2nc(CC(C(=O)O)c3ccccc3OC)cc2-c2ccc(C)cc2)cc1 +CCc1nccc(-c2ccc(C(=O)N3CCN(CCOC)CC3)c(F)c2)c1C#Cc1ccc(N)nc1C +O=C1c2c(c(O)c3nccnc3c2O)C(=O)N1Cc1ccc(Br)cc1F +CCc1cc(CN(CC2CC2)C(CC(=O)O)c2ccc(Cl)c(Cl)c2)ccc1OCCN1C(=O)CCC1=O +CCC(CC)(C(=O)O)c1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1 +CCCNc1nc(C)c(-c2nc3ccccc3s2)c(NC2CC(CO)C(O)C2O)n1 +COc1cc(C)c(Nc2nc(C)cn(C(CF)C3CC3)c2=O)cc1C +Nc1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 +CN1CCC(O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)sc2C(O)(C(F)(F)F)CO3)C1=O +Cc1cc(C(=O)N2CCCCc3ccccc32)ccc1CNC(=O)N1CCCC1C(=O)OC(C)(C)C +CCOc1cc2ncnc(Nc3ccc4c(ccn4S(=O)(=O)c4ccccc4)c3)c2cc1NC(=O)C=CCN(C)C +CC(C)C1CNC(=O)c2cc(-c3cccc(OC(F)(F)F)c3)c(-c3ccc(CN)cc3)n21 +Cc1ncc(-c2ccnc(Nc3ccc(N4CCN(C(=O)CN(C)C)CC4)cc3)n2)n1C(C)C +O=C(NC(C(=O)NC1CCCc2ccccc21)c1cccnc1)c1ccc(-n2cncn2)cc1 +Cc1cccc2c1OP(=O)(OCC1CCC(n3cnc4c(O)ncnc43)O1)OC2 +CC1OC(n2cc(-c3ccccc3)c3c(NCC(=O)N(C)C4CC4)ncnc32)C(O)C1O +Cc1ccc(Nc2nc(-c3ccccn3)cc(N3CCCC(O)C3)n2)cc1 +Cc1cc(OCC2(C(=O)O)CCC2)ncc1-c1cnc(-c2ncc(C(F)(F)F)[nH]2)c(F)c1 +O=C(CCCc1ccccc1)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +COC(=O)OC1Cn2c(-c3ccnc(Oc4ccccc4)n3)c(-c3ccc(F)cc3)c(=O)n2C1 +COc1cc(C(=O)OCCCCN2CC(C)N(CCCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2C)cc(OC)c1OC +CCC1CCCC(C2(OC(=O)N3CCC(O)(CC)CC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCn1c(-c2ccccc2)cc2onc(-c3ccccc3)c2c1=O +O=S(=O)(Nc1ncns1)c1ccc(Oc2ccccc2-c2ccccc2)c(Cl)c1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(CCF)CC1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1cccc(NC(=O)NCCCN2CCCCC2)c1 +O=C(NC1C(CO)OC(n2cnc3c(NC4CCCC4)ncnc32)C1O)c1ccc(Cl)c(Cl)c1 +Cn1c(CF)nc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c21 +COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1 +O=C(c1ccc(OC(F)(F)F)cc1)c1ccn(-c2cc(F)c(O)c(F)c2)c1 +Nc1ncc2cc(Cc3nnc4ccc(-c5ccccc5)nn34)ccc2n1 +O=C(Nc1ccc(C2CCNC2)cc1)c1ccc(Cl)cc1Cl +Cc1nc(CNc2nc(OCC3CC3c3ccc4ncccc4n3)nc(Cl)c2C)n(C)n1 +O=C(Cn1cncn1)c1ccc2[nH]c3c4c(c5c(c3c2c1)C(=O)NC5=O)CCC4 +O=C(NS(=O)(=O)C1CC1)c1cc(Cl)c(OC2CCC(F)(F)CC2)cc1F +CCCCc1ccc(NC(=O)CSc2nnc(-c3ccccc3N)[nH]2)cc1 +Cc1ccc2c(-c3nnc(SCCCN4CCc5cc6nc(C7CC7)oc6cc5CC4)n3C)cccc2n1 +CCCCCCC(NC(CCc1ccccc1)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(N)=O)C(=O)OC)C(=O)O +N#Cc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2C2CNC2)CC1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cccc3ncn(CCc4ccccc4)c2c31 +CCCCCCCCCCCCCCCCS(=O)(=O)NCCCNCCCNCCCCNCCCN +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C(C)=O +CC1COC(c2cccc(OC(=O)NC3CCCC3)c2)=N1 +Cc1c(C(=O)NCCCN2CCN(c3cccc(Cl)c3Cl)CC2)cc(-c2ccccc2)n1C +O=C(NCc1ccc(S(=O)(=O)c2ccccc2)cn1)c1cc2ccncc2o1 +O=C(C=CC=Cc1ccccc1)NCCCCNc1c2c(nc3ccccc13)CCCC2 +Cc1nc2cc(F)ccc2n1C1CC2CCC(C1)N2CCC(NC(=O)c1ccc[n+]([O-])c1)c1cccc(F)c1 +CC1(C)CC(=O)N(CCCCN2Cc3ccccc3C2)C(=O)C1 +C#CCOc1cc(F)c(F)cc1-c1ccc(OCc2cccc(C(=O)N3CCCC3C(=O)O)c2)cc1 +COc1cc2ncnc(Oc3ccc(CC(=O)Nc4ccc(N(C)C)cn4)cc3)c2cc1OC +COc1ccc(C(=O)Nc2ccc(N(C)S(C)(=O)=O)c(OCc3cc(C)ccc3C)c2)cc1OC +CN(C)c1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1 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+Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CCc4ccc(C(=O)c5cccnc5)n4C)c3Cl)c2n1 +Cc1c(Cc2ccc(F)c(C(=O)N3CCC4(CCCN4C)CC3)c2)n[nH]c(=O)c1C +O=C(O)c1ccccc1NC(c1ccccc1)c1ccc(Cl)cc1 +Cc1cccc(NC(=O)NNC(=O)c2cc(-c3ccccc3Cl)nc3ccccc23)c1 +O=C1C(Cl)=C(NCCN2CCOCC2)C(=O)c2cnccc21 +COc1cc2c(cc1OC)C(=O)N1C=C(c3ccc4ccc5cccc6ccc3c4c56)CC1C=N2 +NS(=O)(=O)OCC1CC(Oc2cc(NC3CCc4ccccc43)ncn2)CC1O +Cc1cccc(C2CC2c2ccccc2CCC(=O)O)c1OCc1ccccc1 +Cc1ccc(C)c(N2CCN(CC(O)CN3C(=O)NC(C)(c4ccc(F)cc4)C3=O)CC2)c1 +COC(=O)c1c(SC)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N +CC(=O)OC1=C(c2ccc(C)cc2)Oc2cccnc2-n2cccc21 +CC(C)c1[nH]nc2c1C(c1ccccc1C(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O +O=C1CCc2cc(-c3cncc(-c4cc(F)cc(F)c4)c3)cc3c2N1CC3 +CCOC(O)=C1C(COCCNC(=O)NCCN)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CNC4)cc3)ncc2C(F)(F)F)CC1 +N#Cc1ccccc1Nc1cccc(-c2cnc3ccccn23)n1 +CC(C)(C)OC(=O)c1ncn2c1C1CCCN1C(=O)c1cc(Br)ccc1-2 +CC(Nc1nccc(N2C(=O)OCC2C(C)F)n1)c1ccc(-c2ccnc(C(F)(F)F)c2)cn1 +FC(F)Oc1ccc(-c2ccnc3cc(-c4cc(Cl)ccc4Cl)nn23)cc1OCC1CC1 +CC1(C)CCC(C)(C)c2cc3c(cc21)Cc1ccccc1N=C3c1ccc(C(=O)O)cc1 +O=C(Cn1cc(Cc2cnc(C(F)(F)F)nc2)c(=O)nc1SCc1ccc(F)cc1)N1CCN(c2ccc(Cl)cc2)CC1 +CCC1C(=O)N(C2CCN(C(C)CC(c3ccccc3)c3ccccc3)CC2)c2ccccc21 +CN(C)c1ccc(-c2cc(=O)c3cc(OCCOCCF)ccc3o2)cc1 +CC(C)CN(NC(=O)C1CCC2(CC1)OOC1(OO2)C2CC3CC(C2)CC1C3)c1cc(Cl)nc(C#N)n1 +COc1cc2c(cc1OC)-c1c(-c3cncn3C)ncn1CC2 +CCSc1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +COc1ccc(C(CCCN)(c2ccccc2)c2ccccc2)c(F)c1 +O=C(Nc1ccc(N2CCN(C(=O)C3CCCO3)CC2)cc1)N1Cc2ccccc2C1 +CCCC(=O)N1CCN(C(=O)c2nc(-c3ccccc3)nc(CCC)c2C(=O)OCC)CC1C +CCCCCNC(=O)Nc1c(CCC)cccc1OCCCn1cnc(-c2ccccc2)c1C +CC(=O)Oc1ccccc1C(=O)OC(C)OC(=O)c1ccc(SCCCO[N+](=O)[O-])cc1 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCC(=O)N(Cc3cc(F)ccc3F)c3ccccc32)n1 +CC(C)c1cccc(-c2nccnc2C2CN(C(=O)c3nc4ccccc4[nH]3)C2)c1 +CC(C)OC(=O)N1CCC(N2Cc3cn(-c4ccc(S(C)(=O)=O)cc4F)nc3C2)CC1 +CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)cs1 +CSC1OC(c2ccc(C)c(Cc3ccc(OCCCNCC(C)(C)CN(C)C)cc3)c2)C(O)C(O)C1O +Cc1ccc2c(c1)CNC1CCc3cc(O)c(O)cc3C21 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1cccc(F)c1)Oc1c(F)cccc1-3 +Cc1ccc2c(OCCN3CCC(Cc4cccc(N5CC(C)NCC5C)c4)CC3)cccc2n1 +Nc1ncnc2c1c(-c1ccc3ccccc3c1)nn2CC1CC1 +Nc1cccc(C2=NC(c3ccc(F)cc3)(c3ccc(F)cc3)CN2)c1 +O=C(NC1CC1)c1cnn2ccc(N3CCCC3c3cc(F)ccc3OCCN3CCOCC3)nc12 +CC(NC(=O)C1(NC(=O)c2ccnnc2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F +COC(=O)c1ccc(-c2sc(N)nc2-c2ccc(P(=O)(O)O)o2)cc1 +C=Cc1nn(-c2ccc(F)cc2)c2c1CCCC2Cc1cccc2ccccc12 +CSCC(NC(=O)c1cccc(CNC(=O)C(N)CS)c1)C(=O)O +c1ccc(-c2c[nH]c(-c3cc4c([nH]c5ccccc54)c(C4CCCCC4)n3)n2)cc1 +CN(C)C(=O)Oc1ccc(CC(Nc2ncncc2-c2ccccc2)C(=O)O)cc1 +COc1ccc(C(=O)NC(C)c2cccc(C(=O)Nc3ccc4c(c3)CN(C)CC4)c2)cc1OC +CC(C)N1CCC(Oc2ccc(CN3CCOCC3)cc2)CC1 +COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2coc(C)n2)cc1 +NC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2ccccc12 +Fc1ccc(-c2[nH]c3cc(C4CCNCC4)ccc3c2-c2ccncc2)cc1 +CCOc1cccc(F)c1C1CC(C)C(=O)N1Cc1ccc(OC(F)F)c(Cl)c1 +Fc1cccc(Cl)c1CNc1nc(-c2ccccc2)n[nH]1 +COc1cc(CSc2ncccc2C(=O)Nc2cc(C)cc(C)c2)ccn1 +CCn1c(C(C)NS(=O)(=O)c2ccc(C#N)nc2)nc2cnc(C3CC3)cc21 +NC(=O)C=Cc1cccc2c1nn1cc(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc21 +COc1ccc(C(=O)CSc2cnnn2C2CCCCC2)cc1OC +FC(F)(F)Cn1cc(-c2cnc3nnn(Cc4ccn5nccc5c4)c3n2)cn1 +C#Cc1cccc(Nc2ncnc3ccc(OCCCCCC(=O)NO)cc23)c1 +CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1 +CCCn1ncc(CN2CCCC(C(=O)c3cccc(OC(C)C)c3)C2)c1C +O=C(Nc1ccccc1Br)Nc1ccc(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1Br +Cc1cc(C)cc(S(=O)(=O)N2CCCC2C(=O)NC(Cc2ccc(NC(=O)CCCNC(=N)N)cc2)C(=O)O)c1 +CC(NC(=O)c1nn(-c2ccc(Cl)c(Cl)c2)c2c1CCCC2=Cc1ccc(Cl)s1)c1ccccn1 +CN(C)CCn1cnnc1-c1cc(Oc2ccc(NC(=O)NN=Cc3cccc(O)c3)cc2F)ccn1 +O=C(Nc1nc2c(s1)CNCC2)N1CCC(N2CCc3ccc(F)cc32)CC1 +Cn1c(-c2ccsc2)c(C2CCCC2)c2ccc(C(=O)NC3(C(=O)Nc4ccc(C=CC(=O)O)cc4)CCCC3)cc21 +O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2cc(NCCO)ncn2)cc1 +NS(=O)(=O)c1cccc(N=Nc2ccc(NCS(=O)(=O)O)cc2)c1 +CN1c2ccc(OC(=O)Nc3ccc(Cl)cc3)cc2C2(C)CCN(CCc3ccccc3)C12 +NCCNc1ccc2c3c(nn2CCO)-c2c(O)ccc(O)c2C(=O)c13 +NS(=O)(=O)c1ccc(NNSC(=S)N2CCOCC2)cc1 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+CCCc1nc2c(Cl)ccnc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2c(c1)CC(=O)N2 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CCc4ccccc4)cccc3nc2-1 +c1ccc(Cn2cc(-c3ccnc4ccccc34)c(-c3ccccn3)n2)cc1 +O=C(Nc1ccc(-c2ccnc3[nH]cnc23)cc1)Nc1cccc(Cl)c1 +Cc1cnn(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C3CC3)n2)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CCC(F)(F)F)ncc3F)C2)cc1 +CCCCCCCCCC[N+](C)(CCCCCCCCCC)CCCC1(O)CCC2C3CCc4cc(O)ccc4C3CCC21C +CN(C(=O)c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F)C1CCN(C(=O)c2ccco2)CC1 +O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OC4CCCCC4O)cc3)cc12 +Cc1[nH]nc(O)c1C(c1ccc(OCc2ccncc2)cc1)c1c(O)n[nH]c1C +O=C(NC1CCCNC1)c1ccc(O)c2[nH]c(-c3ccccc3)nc12 +C=C1C(=CC=C2CCCC3(C)C(C(C)OCC(=O)OC(C)(CC)CC)=CCC23)CC(O)CC1O +CCN(CC)CCC1=C(C(C)c2ccccn2)c2ccccc2C1 +COc1ccccc1Oc1ccc(Nc2c(C#N)cnn3cc(NC(=O)NCCN4CCOCC4)c(C)c23)cc1 +Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)C2)c2ccc(Cl)cc12 +CC1(C(=O)NC(Cc2ccc(NC(=O)c3ccnc4ccccc34)cc2)C(=O)O)CCCCC1 +CCCCc1nc(SCC(F)(F)F)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 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+CCCCCCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 +CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C(F)F)cccc32)c1 +CC(C)c1cc(-c2ccccc2)cc(CC2CCCCC2)c1OCC(O)CC(O)CC(=O)O +NC1=NC2(CO1)c1cc(NC(=O)c3ncc(Cl)cc3F)ccc1OCC21CC1 +COCC(=O)Nc1nc(-c2ccc(F)c(C)n2)c(-c2ccc3nccnc3c2)[nH]1 +COc1cncc(-c2cncc(N3CCN(c4ccncc4)CC3)n2)c1 +CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)no1 +CC(=O)Nc1c(-c2ccccc2)cccc1S(=O)(=O)NC(CCCc1ccc(N)cn1)C(=O)N1CCC(=C(F)F)CC1 +CCCN(CCC)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 +O=C(O)CC(NC(=O)CNC(=O)c1cc(O)cc(NC2=NCCCN2)c1)c1cc(Cl)cc(Br)c1O +O=C(NCCc1cccc(Cl)c1Cl)c1cnc(N2CCN(c3ccncc3)CC2)c(Cl)c1 +Cc1cc(C)cc(C(=O)N(C)C(Cc2ccccc2)C(=O)NCCc2c[nH]c3ccccc23)c1 +COCC(=O)Nc1ccc(F)c(C23COCC2S(=O)(=O)C(C)(C)C(=N)N3)c1 +CC(C)C1=NC2CCC34CC35C(=O)CC3(C)C(C(C)N(C)C)C(O)CC3(C)C5CCC4C2(C)CS1 +N#Cc1cccc(-c2nc(OS(=O)(=O)C(F)(F)F)cc3cccnc23)c1 +COc1ccc2c(c[n+]3c4c2ccc2c5c(cc(c24)CC3)OCO5)c1OC(=O)c1ccccc1F +COc1cc2cncc(Cc3ccc4c(c3)OCCN4C)c2cc1OC +CC(=O)c1sc(NC(=O)NC2CN(CC#N)CCC2CN2CCCC(Cc3ccc(F)cc3)C2)nc1C 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+C=CC(=O)Nc1ccc(C(=O)Nc2ccc(C)c(Nc3nccc(-c4cccnc4)n3)c2)cc1 +O=C(NO)C1CS(=O)(=O)CN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br +COc1ccc(CCNCC(O)COc2ccc(-c3nc(C)c(Cl)[nH]3)cc2)cc1OC +CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc12 +Cc1nc(-c2ncn3c2Cn2ncnc2-c2cc(F)ccc2-3)no1 +Cc1ncc(-c2nccnc2OC2CC(Nc3nc4ccccc4s3)C2)cn1 +CC(C)OC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCc1ccccc1Cl +CC(CO)NCCNC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +Nc1ccc2c(c1)CN(S(=O)(=O)c1ccc(-c3ccc(Cl)cc3)cc1)C(C(=O)C(=O)O)C2 +N=C(N)NCCCC(C=O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)COc1ccccc1 +COc1ccc(C(=O)Nc2ccccc2-c2nnn(-c3ccc(Cl)cc3)n2)cc1 +OC(COc1cccc2[nH]ccc12)CN1CCC(c2csc3ccccc23)CC1 +CS(=O)(=O)CCCOc1cccc2c1ccn2-c1ccnc(NC2CCC(C(=O)N3CCC(F)(F)CC3)CC2)n1 +CCCCCCCCCC(=O)CC(=O)Nc1c(C(C)C)cccc1C(C)C +O=C1NCC2c3c(cccc31)CCN2C(=O)c1ccc(Cl)cc1 +C=CC(=O)Nc1ccc2c(c1)[nH]c1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn12 +O=C1C2=C(C(=O)c3ccccc31)C1(CS2)NC(=O)N(CCO)C1=O +COc1cc(Cl)ccc1OC1CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 +COCCN(C)c1cc(C(=O)O)nc2c(-c3cccc(O)c3)nc(N3CCOCC3)nc12 +Brc1sc2[nH]nc(N3CC4CC3CC4OCCN3CCCC3)c2c1-c1ccccc1 +CCOC(=O)C1(NC(=O)c2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)CC1 +C#CCn1c(=O)c2[nH]c(C=Cc3ccc4c(c3)OCO4)nc2n(C)c1=O +O=C(c1cccc(CN2CCN(c3cccc4ccccc34)CC2)c1)N1CCCCC1 +COc1ccc(C(=O)NCc2ccccc2)cc1CSc1nc2cc(F)ccc2n1CC(=O)O +NS(=O)(=O)c1ccc(CCNC(=O)CCSSCCC(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +COCC(C)Oc1cc(Oc2cc(F)cc(F)c2)cc(C(=O)Nc2nccs2)c1 +Cn1ccc2cc(C=CC(=O)c3ccc(OS(=O)(=O)c4cc(F)cc(F)c4)c4c3OC(C)(C)C=C4)ccc21 +CC(C)(COc1ccn2c(CC3CC3)nnc2c1C(F)(F)F)c1ccc(F)cc1 +O=C(NC1CCc2cccc3c2N(C1=O)C(C(=O)O)C3)C(S)C1CCCCC1 +CN1C2CCC1CC(NC(=O)C(Cc1ccc(Cl)cc1)NC(=O)Cc1ccc(F)cc1)C2 +Cc1cc(OCC2Oc3ccccc3O2)cc(C)c1C(=O)Nc1cc(CC(=O)O)ccc1Cl +Cc1ccc(-c2cccc(C(=O)N3CCCC(C)(C)C3)n2)cc1F +Cc1noc2ccc(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc43)cc12 +Cc1ccc(-c2ncccn2)c(C(=O)N2C3CCC2C(COc2ccc(F)cn2)C3)n1 +Cc1ccc2nc(-c3ccc(OCC4CCN(C(=O)Nc5ccc(Cl)cc5)CC4)cc3)c(NC(C)C)n2c1 +Cc1n(Cc2c3c(cc4c2OCC4)OCC3)c2ccccc2[n+]1CC(=O)c1ccc2ccccc2c1 +Cc1oc2c(O)c(O)ccc2c(=O)c1Oc1ccccc1F +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCN)sc34)cc2F)c1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Cl)cc1 +Cc1cc(OC(CCCCNCc2ccc(Cl)cc2)C(=O)NO)cc(C)c1F +O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2ccc(Br)cc2F)C2C=CC1C21CC1 +COc1ccc(S(=O)(=O)N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(Cc2cccs2)C(=O)NO)cc1 +Cn1c2c(c(CO)c1C1CC1)C(=O)C(N1CC1)=CC2=O +ON=C1CC2(N3CCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2 +Cn1ncc(NC(=O)c2nc(-c3ccccc3F)cnc2N)c1N1CCC(N)C(F)CC1 +OC1CCN(Cc2ccccc2)CC1N1CCC(c2ccccc2)CC1 +CC(C)C(Cl)C(NC(=O)C(O)Cc1ccccc1)C(=O)N1C(C(=O)NCCCCNC(=N)N)CC2CCC(O)CC21 +Nc1ncnc(N2CCC(c3nc(-c4cccc(F)c4)cn3CCN3CCCC3)CC2)c1C1CCC1 +N=C(N)c1ccc(-c2cc(N)cc(-c3ccc(C(=N)N)cc3)c2)cc1 +CCCCCCCCCOc1ccc(N2C(N)=NC(N)=NC2(C)C)cc1Cl +CCCCC(=O)N(Cc1ccc(C(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 +CN1CCC(c2c[nH]c3ccc(NC(=O)C4CCCCC4)nc23)CC1 +CC(C)(C)c1ccc(NC(=O)C2=CCN(c3nccs3)CC2)cc1 +CCOc1ccc(S(=O)(=O)N(CC(=O)NN=C2C(=O)Nc3ccccc32)c2ccc(C)cc2)cc1 +Nc1nc(-c2cccc(Cl)c2)c(-c2ccc3ncccc3n2)s1 +C1=C(c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)CCOC1 +N#Cc1c[nH]c2c(NS(=O)(=O)c3ccc(N)nc3)cccc12 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCC(=O)N(Cc3ccc(C(F)(F)F)cc3)c3ccccc32)n1 +O=C(NCc1ccc(S(=O)(=O)C2CCN(CC(F)(F)F)CC2)cn1)c1cc2ccncc2o1 +CC1=NOC(CN2CCC(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)C(C#N)C2)C1 +COc1ccccc1N1CC2(CCN(CCCSc3nnc(-c4ccccc4)n3C)CC2)C1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C(N)=O)CC1 +CCOC(=O)C1C2C(=C(O)OCC)C(C)=NC1(C)Sc1ccccc12 +Cc1cc(-c2cc(C(=O)NC3C4(C)CCC(C4)C3(C)C)c(=O)n(Cc3ccc(F)cc3)n2)ccc1Cl +O=C(Nc1ccccn1)Nc1cccc2c1-c1cccn1C2=O +CN(C)CCNC(=O)c1cccc2cc3ccc(F)cc3nc12 +Cc1cc(N2CCOCC2)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +CNC1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(Cl)c(O)c(OC)c4)cc23)CC1 +CN(C)CCc1c[nH]c2ccc(N=C(N)c3cccs3)cc12 +CCC(CC)Nc1nc(OC)c(-c2ccc(Cl)cc2Cl)nc1C +O=C(Nc1ccc(C2CNCCO2)cc1)c1ccc(N2CCOCC2)nc1 +Cc1ccoc1-c1nnc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)s1 +COc1cc(CNC2CCCC2)cc2[nH]c(=O)c3c(c12)NCCC3 +CCCCCCCCCCCCC(C)OC(=O)C(C(=O)Nc1c(OC)cc(OC)cc1OC)c1ccccc1 +CCOCCOc1cc2c(ccn2C(=O)NC)cc1Oc1ccnc(NC(=O)c2ccc(C3CCN(CC(C)O)CC3)cc2)c1 +CN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 +Cc1ccc(C(=O)NCC(=O)O)cc1-c1ccc2c(C)cc(Oc3ccc(C(=N)N)cc3)nc2c1 +COc1ccccc1Oc1cc(N2CCC(Oc3ncc(F)c(N)n3)CC2)ncn1 +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)C1CCCCC1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4(CCCOC4)C3)n2)cc1OC(F)F +O=C(Nc1cn(CC=CCN2CCOCC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +Oc1nc(-c2cc(-c3ccon3)n(Cc3ccccc3)n2)ncc1F +COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc3cc[nH]c3c2)n1 +O=C(NCc1nnn[nH]1)C1NC2(CCCCC2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(Cl)c1F +O=S(=O)(Nc1nccs1)c1ccc(Oc2cc(C(F)(F)F)nn2-c2ccccc2F)c(F)c1 +Cc1c(N(Cc2cccc(OC(F)(F)F)c2)S(=O)(=O)C2CC2)sc2ccccc12 +Cc1ccc2occ(CNCc3ccc(S(N)(=O)=O)cc3)c(=O)c2c1 +Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +Cc1ccn(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)n1 +CC(C)S(=O)(=O)c1ccc2c(c1)nc(CC(C)(C)C)n2CC1CC1 +O=C(NNc1ccc(N(CCCl)CCCl)cc1)Nc1cc(-c2ccccc2F)nc2ccc(N3CCCC3)cc12 +CCCC(=O)Nc1ccc(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3cc(N)c(F)c(C)c3Cl)c2)cc1 +CCOC(=O)CCCCOc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1 +O=C(CCC(=O)c1cccs1)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +O=C(c1ccc(F)cc1)C1CCN(C2CN(Cc3ccccc3)CCC2O)CC1 +NC(CCCCNC(=O)OCc1ccccc1)C(=O)N1CCSC1 +O=C(Nc1cncc(F)c1)N1CC2(CCN(Cc3cccc(Oc4ccc(Cl)cc4)c3)CC2)C1 +Cc1cc2nc(C(C)CNC(=O)c3ccc(-n4cnnc4)cc3Cl)[nH]c2cc1C +O=C(Nc1ccc(Cl)nc1)Nc1ccc(C2CNCCO2)cc1Br +CCNCCN(Cc1ccc(-c2ccc(Cl)cc2)cc1)C(=O)Cn1cc(Cc2cnn(C)c2)c(=O)nc1SCc1ccc(F)cc1 +CCC(C)C(N=C(S)Nc1cccc2ccccc12)C(=O)NC(C=O)Cc1c[nH]c2ccccc12 +COc1ccc(Sc2cc3ccccc3[n+](CCCCCC3CCCCC3)c2)cc1 +O=C(OC1CCCCC1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CC(=O)N1CCN(c2ccc(CN(CC(F)(F)F)S(=O)(=O)Cc3ccccc3)cc2)CC1 +Cn1c(-c2ccccc2)nc2c(N)nc(C#CC3(O)CCCCC3)nc21 +COC(=O)N1CCC(c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)CC1 +Cc1noc(C)c1C(=O)NCC1CN(c2ccc(CNC(=O)c3ccc(Cl)s3)cc2)C(=O)O1 +O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1ccc(Br)s1 +Cc1c(Cc2ccc(=O)n(CCCC(F)(F)F)n2)c2cc(F)ccc2n1CC(=O)O +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(CNCc2ccccc2)cc1 +OCC1CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)C1 +Oc1ccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)cc1 +O=C(c1ccc(-c2cnn3cccnc23)cc1)N(c1ncccc1Cl)C1CCCNC1 +CCCCc1ccc(CN(CCc2ccc(CC(=O)O)cc2)S(C)(=O)=O)cc1 +COc1ccc(F)c(-c2ccc(COc3cccc(C(CC(=O)O)C4CCC4)c3)cc2C(C)(C)C)c1 +Cc1cnc2ccccc2c1Nc1ccc(N2CCN(C)C(C)(C)C2)cc1 +N=C(N)SCCOc1ccc(C2CCC(O)(CC(=O)O)CC2)cc1 +CC1CCc2cccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c2C1 +O=C(O)Cn1c(SCc2cccc(Cl)c2)nc2ccccc21 +Nc1ncc(C2CCC(O)CC2)nc1-c1ccc(C(=O)NC(CO)c2cccc(C(F)(F)F)c2)c(F)c1 +CC(=O)NC1CCN(c2ncnc3ccc(C#CCNC(=O)c4cccn(Cc5ccc(F)c(F)c5)c4=O)cc23)C1 +Cn1cc(CCCCN2CCC3(CC2)OCc2ccccc23)c2ccccc21 +CC(C)CC(C(=O)NCC(=O)CNS(=O)(=O)c1ccccn1)c1cccc(-c2ccccc2)c1 +O=C(Nc1ccc(Oc2cccc3[nH]c(=O)[nH]c23)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C(O)c1ccc2c(c1)[nH]c(=O)c1ccccc12 +CC(C)CN(c1ccc(C(O)(C#Cc2cccnc2)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NCc4ccccc4-n4cncn4)nc23)N1 +CC(Nc1ncc(F)c(N2C(=O)OCC2CF)n1)c1cnc(-c2ccc(Cl)cc2)s1 +CC(=O)c1csc(CNC(=O)C2C(C(=O)NCC3CCNCC3)C3C=CC2C32CC2)n1 +CCC(C)Nc1nc2ccc(-c3ocnc3-c3ccccc3F)cc2s1 +COCCCn1c(NC(=O)c2cccc(C#N)c2)nc2cc(C(=O)NCc3cccc(OC)c3)ccc21 +COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CCN(CC(=O)N4CC(O)C4)CC3)cc12 +CC(C)Oc1cccc(C(=O)C2CCCN(Cc3cnc(N4CCOCC4)s3)C2)c1 +Cc1cc(C)nc(C(=N)Nc2nc(-c3ccccn3)cc3ccccc23)n1 +COc1cc(S(=O)(=O)c2ccc(F)c(F)c2)cc2c3c(oc12)CCNC3 +CC1CC(C)CC(C)C(O)C(C#N)=CC=CCC(C2CCCC2C(=O)O)OC(=O)CC(O)C(C)C1 +O=C(NC1CCN(Cc2ccccc2)CC1)c1cc(-c2ccc(F)cc2)cc(-n2cnnn2)c1 +CC1c2c[nH]nc2-c2ccccc2N1S(=O)(=O)c1ccc(Cl)cc1 +COC(=O)C1C2CCC(CC1c1cc3ccccc3[nH]1)O2 +CCOc1ccc(-c2nc(NC(=O)C(C)N)sc2-c2cc(OC)c(OC)c(OC)c2)cc1 +CC(C)CNCc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2N)cc1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2=O)nc(N2CCOCC2)n1 +CC1(c2cc(NC(=O)c3ccccn3)ccc2F)N=C(N)OCC1(F)F +Cc1[nH]c(-c2ccccc2Oc2ccccc2)c2c1C(=O)CCC2 +CC(=O)NCC1CN(c2ccc(-c3ccc(Cn4ncnn4)cc3)c(F)c2)C(=O)O1 +CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCSC2)c1 +Cc1c(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cnn1C +CCCCOC(=O)NC(CNC(=O)CC1CC(c2ccc(C(=N)N)cc2F)=NO1)C(=O)O +COCCOc1ccc2c(c1)C1(N=C(N)N(C)C1=O)C1(CCC(OC)CC1)C2 +CCNC(=O)Nc1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O +O=C(O)COc1ccc(Nc2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)cc1 +CCCC(NC(=O)C(C#N)=Cc1cccc(C=C(C#N)C(=O)NC(CCC)c2ccccc2)c1)c1ccccc1 +COCCN1CCN(C(=O)c2sc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[n+]2[O-])CC1 +CC1CN2CCN(Cc3cccnc3)CC2CC1(C)c1cccc(O)c1 +CCNC(=O)Nc1ccc2ncc(Nc3cccc(C)c3)nc2n1 +CCOC(=O)C1=CCCCC1S(=O)(=O)Cc1ccsc1 +CC(Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1cc(CO)ccc1Cl +COc1cc(C(=O)N2CCOCC2)ccc1Nc1ncc(Br)c(OC)n1 +CCS(=O)(=O)c1ccc2cc1CNC(=O)C(Nc1ccc3c(N)nccc3c1)c1ccc(cc1)CCOC(=O)N2 +O=C(Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)NC1COC1 +CCCC(C)COc1ccc(C(CNCC(C)CC)NC(=O)C(C)c2ccccc2)cc1 +CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)cc4)nc3c2)ccn1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC3CCC3)n1)CCN2 +Cc1cc(-c2cccc(Oc3ccc4c(c3)c(=O)ncn4Cc3c(F)cc(F)cc3F)c2C(F)(F)F)cnc1N +O=C(NC1CCc2ccccc21)C(=O)c1c[nH]c2ccccc12 +CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 +CNCCC#Cc1cc(Cl)c(C2(C)CS(=O)(=O)C3(CCC3)C(=N)N2)s1 +CCN(CC)CCn1nc2c3c(c(NCCN4CCNCC4)ccc31)C(=O)c1ccccc1-2 +COCCNCc1cc(C2(C)CCSC(N)=N2)c(F)cc1F +O=C(O)c1ccc2c(c1)nc(-c1ccc(OC(c3ccc(Cl)cc3)c3ccc(Cl)cc3)cc1)n2C1CCCCC1 +[C-]#[N+]c1ccc(N2C(=O)C(C)(C)N(c3ccccc3C(=O)O)C2=S)cc1C(F)(F)F +COc1cc(Nc2ncc3ccn(-c4ccc(SC)cc4)c3n2)cc(OC)c1OC +CCCC(C)COc1ccc(C(CNCc2ccccn2)NC(=O)C(C)c2ccccc2)cc1 +CN(CC=Cc1cccc(C(F)(F)F)c1)Cc1ccc2c(c1)OCCC2 +COc1ccccc1CNC(=O)c1cn2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc2n1 +Cc1cccc(N2CCN(CC(O)COc3ccccc3C(=O)CCc3ccccc3)CC2)c1C +COc1cc(OC)c(C=CC(=O)C=Cc2ccc(N(C)C)cc2)c(OC)c1 +CCOc1cccc2cc(C(=O)N3N=C(c4cccnc4)CC3c3ccccc3O)oc12 +O=C(Nc1ccccc1)N(Cc1cc(Br)cc(Br)c1O)c1ccccc1Br +COc1ccc2cccc(C(CO)CNC(=O)C(F)F)c2c1 +CCCCCCCC#CC1(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C(NC(=O)CS(C)(=O)=O)C(=O)N1 +COc1ccccc1Cn1cc2nc(-c3ccco3)nc(N)c2n1 +OCCn1cc(-c2cc(-c3cnn(CCO)c3)c3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +Cc1ccncc1-c1ccnn2c(-c3cc(Cl)cc(Cl)c3)cnc12 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2cccc(CC(F)(F)F)c2)c1)C(F)(F)F +COc1cc(OC)c2c(c1)OC(c1ccc(OC(=O)Nc3ccccc3)c(OC)c1)CC2=O +CC(=O)C1CCC2C3CCC4CC(O)(COCc5ccccc5)CCC4(C)C3CCC12C +CC1OC(=O)C2(N)CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4C#N)cn3)C12 +COc1cc2c(Oc3ccc(NC(=O)c4cc(-c5ccccc5)ccn4)cc3F)ccnc2cc1OCCCN1CCOCC1 +CNC(=O)C(Cc1ccccc1)NC(=O)Nc1n[nH]c(=S)s1 +COc1cc(C)c2cc1C(=O)NCCCOc1cccc(c1)Sc1cc-2nc(N)n1 +CCN(CC(CCN1CCC2(CC1)C[S+]([O-])c1ccccc12)c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccccc1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccc(C(F)(F)F)cc2[nH]1)C(F)(F)F +CC(Cc1ccc(OCP(=O)(O)c2ccccc2)cc1)NCC(O)COc1ccc(O)c(NS(C)(=O)=O)c1 +CCCCCCCCn1ncn(-c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)c1=O +CN1CCN(c2ccccc2C(=O)C=Cc2ccc(C=CC(=O)NO)cc2)CC1 +OC1(c2ccc(F)cc2)CCC(N2CCN(Cc3ccccc3)CC2)CC1 +CC(NC(=O)Nc1cc2[nH]nc(-c3cnn(C)c3)c2cn1)c1ccc(Cl)cc1 +COC(=O)C(C)(C)Cn1c(=O)cc(Nc2cccc(C(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O +CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3ccc(OC4CCNCC4)cn3)cc2)no1 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+O=C(O)COc1c(C(=O)O)sc(-c2cccc(NCC3CCN(C(=O)Nc4ccccc4Cl)CC3)c2)c1Br +N=C(CCl)NCCCC(NC(=O)c1ccccc1)C(N)=O +O=C(NCc1cnccn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +O=C1CN=C(c2ccccc2F)c2cc(Cl)c(Cl)cc2N1 +Cc1ccc(C(CNC(=O)c2ccc(C=Cc3ccccc3)cc2)n2ccnc2)cc1C +CCNCCNc1cc(-c2ccc(C(F)(F)F)cc2)c(C#N)c2nc3cc(Br)ccc3n12 +CC(C)S(=O)(=O)CCOC12COc3c(F)ccc(F)c3C1(S(=O)(=O)c1ccc(Cl)cc1)CCC(=O)C2 +CCN(CC)Cc1cccc(Nc2ccnc3cc(Cl)ccc23)c1O +O=C(C=NNc1c(Cl)cc(C(F)(F)F)cc1Cl)NCCCCCCCNc1ccnc2cc(Cl)ccc12 +COc1cc(-c2nc(-c3ccccc3)c(-c3ccc(O)cc3)[nH]2)cc(OC)c1O +CS(=O)(=O)Nc1ccc(-c2ccnc(Nc3ccc(CN4CCOCC4)cc3)n2)cc1 +CC(=O)NC(C)c1ccc(C#Cc2ccc(OC3CCC3)cc2)cc1 +CCCCCOc1ccc(NC(=S)NC(=O)c2cccnc2)cc1C(F)(F)F +O=S(=O)(Nc1cc(Sc2ncn[nH]2)c(O)c2ccccc12)c1ccc2ccccc2c1 +O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CCN(C2CCC(c3ccc(O)cc3)CC2)CC1 +NC(=S)NN=C(c1ccc(O)cc1)c1cccc(C(=O)c2ccc(O)cc2)c1 +N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)s3)s2)cc1 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3cccs3)nc21 +COC1CN(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)C1 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+CCOc1ccc(Oc2c(Cl)cnn(C3c4ccccc4-c4ccccc43)c2=O)cc1 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4cc(OCC(C)(C)CO)ccn4)n3)ccc2[nH]1 +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccc(Br)o2)[nH]c1=O +Cc1cccc(F)c1CN1CC(c2ccc(N3CCN(c4ccccn4)CC3)cc2)C(N(C)C)C1 +CCCCc1noc(-c2ccc(C(=O)NCC3CCCC3(C)C)cc2)n1 +COc1cc(OC)cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccnc(C)n5)ccc43)cc2F)c1 +CC(C)(C)c1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nn1 +CCc1nc(-c2ccc(C(F)(F)F)cc2OC)c(CC)nc1NC(CC)CC +Cc1cc(C#N)cc(C)c1Oc1cc(Nc2ccc(C#N)cc2)[nH]c(=O)c1 +COc1ccc(C(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CN(C)CC4)c2)cc1OC +CC1(O)CCC2C1CC=C(C=O)C(CCC1C(C)(O)CCC3OC(C)(C)C(O)CCC31C)C2(C)C +Cc1nc(C)n(-c2cc(C3CC3c3nc4ccccc4n3C)nc(N(C)C)n2)n1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)cc1-c1csc2ccccc12 +CC(C)c1cccc(C(C)C)c1OC(=O)NC(=O)SCc1ccccc1 +COc1cc(Cl)c2c(c1)C1(CCCCC1)NC(=O)N2 +CCCN1CCC(N(C)C(=O)c2ccc(-n3c(C)nc4ccccc43)cc2)C1 +CCc1nn2c(-c3c(COC)cc(OC)cc3OC)cccc2c1N(CC1CCOCC1)CC1CC1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CC(C#N)C1 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+O=C(Nc1ccc(N(CCCl)CCCl)cc1)Nc1ccc2ncnc(Nc3cccc(Cl)c3F)c2c1 +O=C(NO)c1ncc(COCc2ccc(F)cc2)c(CO)c1O +CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(C2CC(=O)NS2(=O)=O)cc1)C(N)=O +CCOC(=O)c1ccc2cc(Oc3ccnc(C(=O)NC)c3)ccc2c1 +CC(=O)N(C1=C(N2CCCC2)C(=O)c2ccccc2C1=O)c1ccc(F)c(F)c1 +O=C(Nc1ccc(O)cc1)c1cnc2[nH]cc(-c3ccc(O)cc3)c2c1 +Cc1ccc(F)cc1-c1cc2cnc(NC(=O)C3CC3)cc2c[n+]1[O-] +CCC1(c2cccc(O)c2)CCCCN(CCCCCCCCCCCCN2CCCCC(CC)(c3cccc(O)c3)C2)C1 +CC(=O)Nc1cc(-c2ccc(-c3cc(NC(=O)c4ccnc(N5CCCC5)c4)ccc3C)cc2)[nH]n1 +Cn1c(Cc2nc3cc(C(N)=O)ccc3[nH]2)nc2ccc(C(=O)NC(CCCCCP(=O)(O)O)C(=O)O)cc21 +COC1C(F)CN(C(=O)Cn2nc(C(C)=O)c3cccnc32)C1C(=O)NC(C)c1cccc(Cl)c1F +C[S+]([O-])c1ccc(C2CN3CCCC3c3ccccc32)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cncnc32)cc1NC1CC1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2CCc1ccccc1 +O=C(c1ccc2c(c1)c1ccccc1n2CCCl)N1CCCCC1 +NCC1CCC(CNc2nc(NCCc3ccccc3)ncc2[N+](=O)[O-])CC1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1cccc(Cl)c1 +COc1ccc(Cl)c(OC)c1C1CC(F)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 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+O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(N4CCN(c5cc(C(F)(F)F)ccn5)CC4)nc23)N1 +O=C(O)CCCc1nc(-c2cn(Cc3cc(Br)c(Br)c(Br)c3)nn2)no1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 +CC(C)c1cc(-c2ccc(F)cc2)c(OCC(O)CC(O)CC(=O)O)c(C(C)C)c1 +COc1ccccc1N1CCN(Cc2cn3cc(C)cc(C#N)c3n2)CC1 +CS(=O)(=O)c1ccnc2c1c(Sc1ccc(Cl)cc1)c1n2CCCC1CC(=O)O +O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc3ccccc3c2)=C1c1nn[nH]n1 +CC(C)(C)Nc1nc2c(-c3cc4c([nH]3)CCNC4=O)cccc2nc1Cl +O=C(COc1ccccc1)N1CCCCC1c1nnn(-c2ccc3[nH]ccc3c2)n1 +CC(C)c1ccccc1OCCN1CCC(N(C)S(=O)(=O)c2cnn(C)c2)CC1 +O=C(Cc1ccccc1)NC1CCN(CC(=O)NC2CCc3cc(F)ccc3C2Cc2cccnc2)CC1 +N#CC(c1cccnc1)N1CCN(C(=O)C=C(c2ccccc2)c2ccccc2)CC1 +Cc1cc(N=c2[nH]c(=O)[nH]c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C +CC(C)CCn1c(=O)ccc2cnc(Nc3ccccc3)nc21 +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N3CCNCC3)nc2c1 +O=C1c2ccccc2SC(c2ccc(Cl)cc2)N1CCCCNc1ccnc2cc(Cl)ccc12 +O=C(O)C(O)=CC(=O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccccc2)c1=O +COC1Nc2c(ccc(C)c2O)C(=O)N2C=C(C=CC(N)=O)CC12 +CC(C)c1ccccc1OCCNCCCCN1C(=O)C2CCCN2C1=O +CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccccc1 +OCCNc1nc(NCCc2ccccc2)c2cnn(C=Cc3ccccc3)c2n1 +Cc1c(C(C)c2c(F)cccc2F)nc(N2CCC(C)CC2)[nH]c1=O +CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4cnc(C)nc34)c2Cl)cc1 +C[n+]1c2n(c3ccccc31)N=C(c1ccccc1)CS2 +NCCCCN(Cc1nccc2c3ccccc3n(CCCN3CCNC(=O)C3)c12)C1CCCc2cccnc21 +Cn1cc(C=CC(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc4ncccc4c3)cccc21 +N=C(Nc1ccc(F)c(CSC2CCCC2)c1)c1cccs1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(OC4CCOCC4)c3Cl)C2)cc1 +CC(C)NC1CCC(n2cc(C(N)=O)c(Nc3ccc(S(=O)(=O)C(F)(F)F)cc3)n2)C(C#N)C1 +Cc1c2c(cc[n+]1Cc1ccccc1)c1ccc(OCc3ccccc3)cc1n2Cc1ccccc1 +CCCCOc1cc(C(=O)NC(CCC(=O)O)C(=O)N2CCN(C(=O)OC(C)C)CC2)nc(-c2ccccc2)c1 +COCN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +Cn1c(=O)c2c(CC(=O)Nc3nc(-c4ccc(C(F)(F)F)c(F)c4)cs3)nsc2n(C)c1=O +Cc1ccc2nc(N(C)C)nc(NCc3ccc(C(=O)NC4CCN(Cc5ccc(F)cc5)CC4)cc3)c2c1 +CCN(CC)c1ccc2cc(C(=O)NCC3NC(CO)C(O)C3O)c(=O)oc2c1 +CC(CCc1ccc(-c2ccc(NS(C)(=O)=O)cc2)cc1)(C(=O)NO)S(C)(=O)=O +COCCNc1cc(-c2ccccc2Cl)c(N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cn1 +COc1ccccc1-n1nc2c(c1C(C)C)C(C)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O +NC1CCCC(NC(=O)c2ccc(O)c3[nH]c(C4CC5CCC4C5)nc23)C1 +CCc1nc(N)cc(OC)c1-c1ccc2c(c1)N(CCCOC)CCC2 +CNc1nc(Cl)nc2c1ncn2C1OC(C(=O)NCCC(c2ccccc2)c2ccccc2)C(O)C1O +O=C(NCCCN(C1=NS(=O)(=O)c2ccccc21)c1cccc(F)c1)c1ccc(F)cc1 +COc1ccc(C#Cc2cccc(C(=O)O)c2)cc1Cc1cnc(N)nc1N +COc1cc2c(cc1OC)C(c1ccc(Cl)cc1Cl)CN(Cc1cnc(N)nc1N)C2 +C[N+]1(CC2CC2)CCc2c(sc(NC(=O)Nc3ccc(Cl)cc3)c2C(N)=O)C1 +Cc1ccc(C(=O)NC2CCOCC2)c(F)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +C=C(c1c(C)c(C)cc(Cl)c1OCC(O)CNC(C)(C)C)n1ccnc1 +COc1cccc(C2(O)CCCCC2N2CCC3(CC2)C(=O)NCC3c2ccc(F)cc2)c1 +CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1C +Cc1csc(NC(=O)c2cc(Oc3ccccc3)cc(Oc3cccc(S(C)(=O)=O)c3)c2)n1 +CC(=O)OC1CCCC(NC(=O)Nc2cc3[nH]nc(-c4ccnc(C)c4)c3cn2)C1 +CCN(C)c1nccc(N2CCC(Oc3ccc(C(C)NC(=O)c4cn[nH]c4)cc3)C2)n1 +CC1(C)Cc2ccc(C#N)cc2C1NC(=O)c1cc2cc(Cl)ccc2[nH]1 +CCN(CC)c1nc(Nc2ccc(S(N)(=O)=O)cc2)nc(N(CC)CC)n1 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+CCNC(=O)c1ccc2nc(C)c3nnc(-c4cccnc4OC)n3c2c1 +C=Cc1csc2c(NCC(N)Cc3ccccc3)nc(-c3ccncc3)nc12 +O=C1OCCc2cc(C3CN4CCN(C(=O)Cc5cnc(-n6cnnn6)nc5)CC4CO3)ccc21 +COc1ccccc1COCCCOc1ccc(N2C(=O)CNCC2COCc2ccc(C)cc2)cc1 +CN1CCN(c2nc3ccccc3c3c2CN(C)CC3)CC1 +O=C(NO)c1cnc(NC23CC4CC(CC(C4)C2)C3)nc1 +N=C(NCCO)c1c(O)nsc1Nc1ccc(Nc2ccc(Br)cc2)cc1 +COc1cc(OCc2csc(N(C)CCO)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C#Cc1ccc2ccc3cccc4ccc1c2c34 +CC(NC(=O)C(C)(F)F)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 +Cn1nccc1-c1cc(C(F)(F)F)ccc1N1CCOc2cc(S(=O)(=O)Nc3ncns3)ccc21 +Cc1nccn1-c1cc2nc(O)c(O)nc2cc1[N+](=O)[O-] +CC1CCCN1CCCOc1ccc(C(=O)CN2CCN(C(=O)c3cccn3C)CC2)cc1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1cccc2cccc(Cl)c12 +Cc1cc(NCC(N)c2cccs2)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +CN(C)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3CCc2ccccc2)cc1 +COc1cccc(NC(=O)c2ccc(-n3cccn3)c([N+](=O)[O-])c2)c1 +COc1ccc(-c2nc(COc3ccc4c(ccn4CC(=O)O)c3)sc2-c2ccc(C(F)(F)F)cc2)cc1 +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)Nc3ccc(F)cc3F)nc12 +[N-]=[N+]=Nc1ccc(COc2ccc(C(O)CCC(=O)O)cc2)cc1I +Cc1cccc(Nc2ccccc2C(=O)NCCC(=O)NCCCCCCCNc2c3c(nc4ccccc24)CCCC3)c1C +CNCCCOc1c(C)cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)cc1C +CCOC(=O)C=C1C2C3C=CC(CC3)C2C(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCOC(=O)c1cc(CCn2cnc3c2NC=NCC3O)c2c(c1Br)CCCC2 +Cc1cncc(C(=O)Nc2csc(CN3CCC(C(=O)NC(C)(C)C)CC3)c2)c1 +CS(=O)(=O)c1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +O=C(O)CCCCC=C(c1cccnc1)c1cccc2ccccc12 +Cn1nc(C(C)(C)C)c(C#N)c1-c1nc2nc(-c3ccccc3C(F)(F)F)cc(N3CCOCC3)c2[nH]1 +CC(O)c1cccc(-c2nnc(N3CCC(N4CCCCC4)CC3)s2)c1 +C=CC(=O)Nc1cccc(CN2C(=O)N(C)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc32)c1 +O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCn2cccc2C1 +CCCCCCCC1=CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 +CCc1nc2nc(C)cc(Nc3ccc(C(F)(F)F)cc3)n2n1 +C=C(c1ccc(N(C)C)cc1)c1cc(OC)c(OC)c(OC)c1 +CCCc1cc(-c2cccc(S(C)(=O)=O)c2)nc(C#N)n1 +O=C1CCc2ccc(OCCCCN3CCN(c4cccc5[nH]c(=O)oc45)CC3)cc2N1 +Cc1ccc(C2CC(c3cc(Cl)ccc3O)=NN2C(=O)c2ccco2)cc1 +O=C1NC2(CCCC2)CN(Cc2ccc3cc4c(cc3n2)CC2(C4)C(=O)Nc3ncccc32)C1c1ccccc1 +NC(=O)Nc1sc(C#Cc2ccccc2F)cc1C(N)=O +COc1ccc2c(c1)CCN1C(=O)C3CCCC(C21)N3S(=O)(=O)Nc1cc(F)c(F)cc1F +CC(Cc1cnc2nc(N)nc(N)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +CCCCc1c(C)[nH]c2c(-c3ccccc3)c(C)nn2c1=O +O=C(O)C(Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1Br +COc1cc(O)c2c(=O)c(OC)c(-c3ccc(OC)c(OC)c3)oc2c1 +C=C(Br)CN1C2CCC1C(C(=O)OC)C(c1ccc(I)cc1)C2 +NC(C(=O)N1CCSC1)C1CCC(NC(=O)OCc2ccc3ccccc3c2)CC1 +COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC1CCNCC1 +CCCCCC(O)C=CC1C(O)CC(=O)C1CCSCCCC(=O)O +CN1C2CCC1CC(N(c1ccccc1)c1ccc(C(=O)N3CCCC3)cc1)C2 +COc1cncc(NS(=O)(=O)c2ccccc2C(F)(F)F)c1 +CN(C)c1ccc(-c2nc3ncnc(N)c3c(-c3ccccc3)c2-c2ccccc2)cc1 +NC1CCC(Nc2ccn3ncc(-c4ccc5ccccc5c4)c3n2)CC1 +CCn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C +CN(C)CCOC(=O)N1CCC(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)C(C#N)C1 +Cc1c(COc2ccccc2-c2cccc(N3CCC4(C(=O)O)CC4C3)n2)ccc2c1CCN(C(C)c1ccccn1)C2 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+O=C1NC(=S)NC(=O)C1=NNc1ccc(S(=O)(=O)N2CCc3ccccc32)cc1 +CCC1(O)c2cc3n(c(=O)c2COC(=O)C1OC)Cc1cc2cc4c(cc2nc1-3)OCO4 +Nc1cccc(CN2C(=O)N(Cc3ccc4[nH]ncc4c3)C(Cc3ccccc3)C(O)C2CCc2ccccc2)c1 +CNc1cc2c(cn1)cc(-c1ccc(F)c(NC(=O)Nc3cc(C(C)(C)C)no3)c1)c(=O)n2C1CCOC1 +CCc1ncnc(-c2ccc(C(=O)N3CCCCC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +O=C(NC(c1cccnc1)C(F)(F)F)c1cc(OCC2CC2)c(Cl)cn1 +CN1CCN(C2CCC(c3ccc(OCCCN4CCCCC4)cc3)CC2)CC1 +O=C(Nc1ccc([N+](=O)[O-])cc1)c1cc(Cl)ccc1O +COC1=Nc2ccccc2C2=NC(CN3CCN(c4ccccc4Cl)CC3)CN12 +Cc1nc(NC(C)c2cccc(-c3ccnc(F)c3)c2)cc(-c2ccc3ncsc3c2)n1 +COc1ccc(-c2ccc3c(c2)CCc2nn(-c4ccccn4)c(O)c2-3)cc1 +O=C(O)CN1CCN(c2nc3cccc(F)c3n3cccc23)CC1 +Cc1ncccc1OCC1CN(CC(=O)N2c3ccccc3CC2C)CCO1 +CC1c2nnc(-c3cnccn3)n2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl +CCc1cc2c(C(N)=O)nn(CC(=O)N3CC(F)C(OC)C3C(=O)NCc3cccc(Cl)c3F)c2cn1 +Cc1cc(C)cc(NC(=O)CN2CCC(c3cccc[n+]3[O-])CC2)c1 +CN(C)c1ccc(-c2nc3ccc(OCCOCCOCCF)cc3s2)cn1 +O=C(NCCCCN1CCCC1)C1C(C(=O)NCCc2ccccn2)C2C=CC1C21CC1 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+CC(C)(C)c1ccc(C(=O)NC(=S)Nc2ccc(NC(=O)c3ccccc3Cl)c(N)c2)cc1 +Cc1ccc(-c2c3n(c(=O)c4ncccc24)CCCN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C3=O)cc1 +CNC(=O)c1cccc2c(Nc3ccc(NS(C)(=O)=O)cc3N(C)C)c3cccc(OC)c3nc12 +O=C1N(CCN2CCCCCC2)CCN1c1cccc(C(F)(F)F)c1 +CC1=CC(=O)N(Cc2cccc(F)c2)S(=O)(=O)O1 +O=C(O)c1cccc(S(=O)(=O)C2CCc3ccccc3C2)c1 +O=C(O)c1cccc(C=Cc2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C3CCC3)cc2Cl)c1 +CN(Cc1ccccc1)c1cccc2cc(S(=O)(=O)Nc3ncns3)ccc12 +CCc1c(CCN2CCC(C(=O)O)CC2)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 +CCCS(=O)(=O)Nc1cc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c(F)c1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC(C)(C)c1ccccc1 +CCCOC(=O)N1CCC(C(=O)O)=C(Cc2cccc(OCCc3nc(-c4ccccc4)oc3C)c2)C1 +Nc1ccccc1NC(=O)c1ccc(CNCc2nc(-c3ccc([N+](=O)[O-])cc3)no2)cc1 +Cc1cc(-c2cccc(SCC(=O)Nc3ccc(-c4cnccn4)cn3)c2)ccn1 +COCCN1CCn2cc(-c3nc(Nc4ccnn4C)ncc3C)cc2C1=O +CCCCCCCCCCCCCCCCNC(CNC(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1 +Cc1nc(-c2cnccc2Nc2cccc3[nH]ncc23)c2nc[nH]c2n1 +N#Cc1ccccc1CN1CCN(C(=O)CC(N)Cc2cc(F)c(F)cc2F)CC1=O 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+CC(C)N1CCC(OC(=O)C(O)(c2ccccc2)c2ccccc2)CC1 +CC(C)C(S)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)NC(C(=O)O)C(C)C +Cc1cccc(N)c1C[S+]([O-])c1nc2ccccc2[nH]1 +Cc1ccc(Cn2cnc3c(N(C)C)nc(Cl)nc32)cc1 +CCOC(=O)N1CCC2C(CC3C(=O)OC(C)C3C2C=Cc2ccc(-c3ccccc3F)cn2)C1 +N#Cc1c(-c2ccc(Cl)cc2)cc(-c2ccco2)nc1N +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3CCCC3C(N)=O)cc2n1 +CNC(=O)c1ccc(-c2cc(-c3ccc(S(C)(=O)=O)cc3)cnc2N)cc1 +CC(C)(C)C1CCc2sc(-c3nnc(CCl)o3)cc2C1 +COc1ccc(CC(=O)O)cc1C1=NCC(=O)N(Cc2ccc(Cl)cc2)c2ccccc21 +COc1ccc(Nc2cc(-c3cccc(O)c3)nc(N3CCOCC3)n2)cn1 +c1ccc(-c2nnn[nH]2)c(-c2ccc(Cn3c4ccccc4c4ccccc43)cc2)c1 +Nc1cnc(-c2ccc(-c3ccccc3C(=O)N3CCCC(O)C3)cc2F)cn1 +CC(C)C(N)C(=O)Nc1cnc(NCCNc2ccc([N+](=O)[O-])c(N)n2)nc1-c1ccc(Cl)cc1Cl +Fc1cnc(Nc2ccc3cc[nH]c3c2)nc1Nc1ccc2cc[nH]c2c1 +Cc1[nH]cnc1CSCCNC(=N)NCCSCc1nc[nH]c1C +CC(C)(C)OC(=O)NC(Cc1ccc(F)cc1)C(=O)NN=Cc1ccc(O)c(O)c1O +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CNC(C)(C)CO3)cc12 +CN(CCN1CCCCC1)C(=O)N1CCC(C(=O)c2ccccc2)CC1 +CCOc1ccc(OCC2Cc3ccccc3CN2C(=O)c2cccc3ccccc23)cc1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4ccc(N5CCCCC5)nn4)ccn23)c1 +COc1ccc2c(CCCCN3C(C)CCCC3C)cccc2c1 +[C-]#[N+]C1CCCCC1n1cc(C(N)=O)c(Nc2ccccc2)n1 +COCC1(c2ccc(C)cc2)CC(c2ccccc2)=NN1C(=O)Nc1ccc(F)cc1 +CCOc1ncccc1-c1nc(C2CCN2C(=O)c2cc(OC)c(C)cc2-n2nccn2)no1 +c1ccc2nc(NC3=NCC4(CN5CCC4CC5)O3)ccc2c1 +O=c1c2cncnc2ncn1Cc1nc(CCc2ccc(Cl)cc2)no1 +Cc1c(CO)oc2cccc3c2c1cn3S(=O)(=O)c1cccc2ccccc12 +CCCCCCCOc1ccc(NC(=O)Oc2ccccc2F)cc1 +CNS(=O)(=O)c1cnc(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)c(C)c1 +CCN1C(=O)C(NC(=O)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)N=C(C2CC2)c2ccccc21 +COC1CCC2(CC1)Cc1ccc(-c3cncc(C(F)(F)F)c3)cc1C21N=C(N)N(C2CC2)C1=O +O=C(CCCN1C2CCC1c1c([nH]c3ccccc13)C2)c1ccccc1 +N#CCCc1c(-c2ccccc2)c(O)nc2cc(Cl)ccc12 +COc1cc(C)ccc1S(=O)(=O)NN1CCC(C)=C(CC(=O)NCc2ccc(C(=N)N)cc2)C1=O +CC12CCC3C(CCC4Cc5nc6nc7ccccc7n6cc5CC43C)C1CCC2O +CC(CCCCCNS(N)(=O)=O)C1CCC2C(=CC=C3CC(O)CC(O)C3)CCCC21C +Cc1ccc2c(-c3nnc(SCCN4CCc5cc6nc(C(F)(F)F)oc6c(Br)c5CC4)n3C)cccc2n1 +COC(=O)C(NC(=O)c1cc(-c2cc[nH]c2)nc2ccccc12)c1ccccc1 +Fc1ccc(C2CN(CCc3ccc(Cl)cc3)CCC2c2cc(-c3ccc(Cl)cc3)n[nH]2)cc1 +O=C(c1ccc(-c2nc(COc3ccc(-c4nnco4)cc3)no2)s1)C(F)(F)F +CCCOCC1CC2(C)C(O)CCC2C2CCc3cc(O)ccc3C12 +COc1ccc(N2CC=C(c3cccc(Cl)c3)C2=O)cc1OCCN1CCCCC1 +CCOc1ccc(-n2cnc3cc(CNc4ccc(CC)cc4)ccc32)cc1 +CN(C)c1ncc(S(=O)(=O)NC2CCN(C(Cc3cc4ccnc(N)c4cc3C(F)(F)F)C(=O)O)C2=O)s1 +O=C(C1CCCN1C(=O)CCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCCCC1 +CCc1cccc2c1NC(=O)C(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)N=C2c1cccc(C)c1 +CCc1cccc(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 +Cc1nnc2sc(C(=O)NC3CN(c4ccncc4Cl)C3)c(N)c2c1C +O=C(NCc1ccc(F)cc1F)c1c(NCCc2ccccc2)c2cccnc2n(O)c1=O +COc1ccc(NCc2cnc3nc(N)nc(N)c3c2)cc1OC +CCn1ncc2c(NC3CCOCC3)c(C(=O)NCc3ccccc3)cnc21 +CCN(Cc1cnc[nH]1)c1ccc(OC(F)(F)F)c(Cl)c1 +OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)c1ccc(-c2cccc(F)c2)cc1 +CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CCC(N)CC3)c2c1Cl +CCCCNC(=O)c1ccc2c(c1)nc(-c1cccc(Oc3ccccc3)c1)n2C(CCCNC(=N)N)C(N)=O +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)C(N)CO)CC2)cc1 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+O=C(NC1CCOCC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +NC12CC1CN(C(=O)c1cc(NC(=O)c3cc(-c4ncccc4F)c(Cl)cc3Cl)n(-c3ccccc3)n1)C2 +O=C(NO)c1ccc(-c2ccc(CNCCc3ccc(F)cc3)cn2)s1 +Cc1cc(NS(=O)(=O)c2ccc(NCc3coc4ccccc4c3=O)cc2)no1 +NC(=O)c1cc(-c2c[nH]c3ncccc23)cc(NC2CCC(O)CC2)n1 +Cc1nc(C(=O)Nc2ccc(Cl)cc2)sc1C1(C)CC(c2cccc([N+](=O)[O-])c2)=NO1 +CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1F +O=C(NCc1ccccc1)c1ccc(-c2cc(-c3cc4c([nH]3)CCNC4=O)ccn2)cc1 +COc1ccc(CC(=O)NC(=N)NC(CC(C)C)C(=O)NCc2cccc(-c3nnn[nH]3)c2)cc1OC +ON=C1c2ccccc2-c2ccc(OCCN3CCCC3)cc21 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(-c2ccc(O)c(F)c2)cc1F +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3cnc(C(F)(F)F)cn3)cs2)CO1 +Cc1cn(C2CN(CP(=O)(O)O)CC2O)c(=O)[nH]c1=O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CO)cccc3nc2-1 +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCCCCC2)C1 +CN(C)CCc1c[nH]c(-c2cccc(C(F)(F)F)c2)n1 +NC(=O)C=Cc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2 +CC(C)(C)OC(=O)N1CC2CC1CC2Oc1ncnc(Nc2ccc(S(C)(=O)=O)cc2F)c1[N+](=O)[O-] +COc1ccc2c(c1)c(C1=C(Cl)CN(C)C1)cn2S(=O)(=O)c1ccccc1 +Cn1nccc1-c1ccc(F)cc1Oc1ccc(S(=O)(=O)Nc2nccs2)cc1C#N +CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N(CCC(=O)NC1CCCCNC1=O)Cc1ccc(Cl)c(Cl)c1 +C#Cc1cnn2c(NCc3cccnc3)cc(-c3ccccc3)nc12 +Cc1cc(Nc2nc(N3CCC(N)CC3)nc3ccsc23)n[nH]1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ncc(OC(F)F)cc3Cl)cs2)CO1 +CC1(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)CC(c2cccs2)=NO1 +CC(C)N(C(=O)NC1CCC(CCN2CCN(c3nsc4ccccc34)CC2)CC1)C(C)C +Cc1c(NS(=O)(=O)c2ccc(CCCCC3CCN(C)CC3)cc2)c(CC(C)C)nn1C +O=C(O)C(Cc1ccccc1)CC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +COCCNc1ccc2[nH]c(-c3n[nH]c4ccc(OC(C)c5c(Cl)cncc5Cl)cc34)nc2c1 +COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(-c2ncccn2)nc1OCCOc1ncc(C(F)(F)F)cn1 +COc1cc(C=NNC(=O)C(OC)c2ccc(N3CCCS3(=O)=O)cc2)cc(OC)c1Br +Cc1ccnc(Oc2ccc(-c3cc4c(cc3F)ncc3nc(C)n(C5CCN(S(C)(=O)=O)CC5)c34)c(Cl)c2)n1 +COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OCC1CN(C(N)=NC#N)CCCO1 +O=C(Oc1cccc2c1C(=O)C=C(N1CC1)C2=O)c1ccco1 +CC(CC(=O)O)NC(=O)CN1CCCC(CCC2CCNCC2)C1=O +CC(=O)N1c2ccc(NC(=O)CCCCCCC(=O)NO)cc2C(NC(=O)OC(C)C)CC1C +COCCn1cc(Nc2cc(-n3ncc4cc(C#N)cnc43)ncc2C(=O)NCC(F)C(C)(C)O)cn1 +CCCCc1nnc([S+]([O-])Cc2ccccc2C(=O)OC)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2cnc(-c3ccc(F)cc3)o2)cc1 +CC(C)(C)CCn1nc(-c2cccs2)c(O)c(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)c1=O +Nc1ccc(-n2cc(COC3OC(CO)C(O)C(O)C3O)nn2)cc1 +O=C(Nc1ccc(F)c(F)c1)C(=O)c1c[nH]c2ccccc12 +Cc1cnc2c(c1)CCc1cc(Cl)ccc1C2=C1CCN(C(=O)Cc2ccncc2)CC1 +CS(=O)(=O)Nc1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1 +O=C(NCCc1c[nH]cn1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)c2cc1OCCOC +CCCOc1cc(=O)oc2cc(OCc3cccc(Br)c3)ccc12 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(C(F)(F)F)c1O +Cc1ccc(-c2nn(-c3nc(-c4cc5ccccc5oc4=O)cs3)cc2C=O)cc1 +CC12CCC(O)CC1CCC1C2CCC2(C)C(C=NOCCCN)CCC12O +Cc1ccccc1-c1ccc(C(=O)N2CCN(C(=O)c3ccc4cc[nH]c4c3)C(C)C2)cc1F +CCCc1c(O)c(CCCOc2ccccc2)cc2c1CC(CCc1ccccc1)O2 +CCCCN(C)C(=O)OC1=C(c2ccccc2)Oc2ccccc2-n2cccc21 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+N=C(N)NCCCCC1CC(C(=O)NCC(NS(=O)(=O)c2ccc(F)cc2)C(=O)O)=NO1 +O=C(CN1CCCN(C(=O)c2ccccc2)CC(NC(=O)c2nccc3ccccc23)C1=O)NC1CC(=O)OC1O +Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C)c2C)n1 +Cc1ccc2cccc(-n3c(SCC(=O)Nc4ccc(S(N)(=O)=O)cc4Cl)nnc3C(F)(F)F)c2n1 +CCCCCn1c(-c2ccccc2)c(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)c2ccccc21 +COc1ccc(C2=NN(C(=O)Nc3ccc(Cl)cc3)C(CCO)(c3cccnc3)C2)cc1 +Cc1cccc2c1N(C1CCN(S(=O)(=O)c3cccc4cccnc34)CC1)C(=O)OC2 +COc1cc(N(C)C)ccc1OCCOc1c(Br)cc(C=CC(=O)O)cc1OC +CC(=O)c1ccc(Oc2ccc(-c3ccc(-c4cccc(C#N)c4)n3CC(=O)NC(=N)N)cc2)cc1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1cc(CN2CCOCC2)on1 +COc1cc2c(N3CCN(C(S)=Nc4ccc(-c5ccccc5)nc4)CC3)ncnc2cc1OCCCN1CCCCC1 +CC(=CC(=O)NC(CC(C)C)C(=O)N1CC2CC2C1C(=O)NC(C)CCC(N)=O)c1ccc(OP(=O)(O)O)cc1 +CC(C)=CCc1cc(C(=O)Nc2cc3ccc(OCCCN4CCCC4)c(C)c3oc2=O)ccc1O +CC(Oc1cncc(N2CCNCC2)n1)c1cccc(F)c1 +CC(NP(=O)(COC1C=C(F)C(n2cnc3c(N)ncnc32)O1)Oc1ccccc1)C(=O)OC1CCC1 +Cc1ccc(-n2nccn2)c(CN2CCCN(c3ncc4ccccc4n3)CC2)c1 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+COc1ccc(S(=O)(=O)N2CCCN(C(=O)c3ccc(OC(F)(F)F)cc3)CC2C(=O)NO)cc1 +CC(C)Oc1ccc(C=C2C(=O)Nc3cc(Cl)ccc32)c(OC(C)C)c1 +CC1(COCc2ccc(-c3ccc(F)cc3)cc2)Cn2cc([N+](=O)[O-])nc2S1 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ncc(C3CC3)cn2)CC1c1cccc(F)c1 +CCCc1ccc(Cc2ccc3c(c2)C2(OC3)OC(CO)C(O)C(O)C2O)cc1 +Cc1ccc(NC(=O)c2ccc(C)c(NC(=O)C=Cc3cncnc3)c2)cc1F +N#CC1(CNc2cc(-c3ccnc4[nH]c(C5CCNCC5)cc34)c(Cl)cn2)CCOCC1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C(=O)NCCO +CCc1ccc(CN2CCCC(CNC(=O)c3cccc(OC)c3OC)C2)cc1 +C=CC(=O)Nc1ccccc1Nc1cc(N(C)C(=O)Nc2cc(OC)cc(OC)c2Cl)ncn1 +Cc1ccccc1C#CC1(O)CCC2C3OCC4=CC(=O)CCC4=C3C(c3ccc(N(C)C)cc3)CC21C +Cc1cccc(C(=O)NC(CC(C)C)C(=O)NCCN2CCc3ccccc32)c1 +COc1cnc2ccn(C(C)c3nnc4c(F)cc(-c5cnn(C)c5)cn34)c(=O)c2c1 +Cc1ccc(S(=O)(=O)NCCc2ccc(C(=CCCCC(=O)O)c3cccnc3)cc2)cc1 +CC1SC(N)=NC2(c3ccc(F)cc3F)COC(C3CC3)CC12 +CNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1Nc1cnn(C2CCOCC2)c1 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+COc1ccc(OC)c(C(=O)C=Cc2cn(-c3ccccc3)nc2-c2ccsc2)c1 +COc1c(F)cc2nc(-c3c(N)n[nH]c3C)sc2c1Cl +CCCSc1ncncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 +CCCCCCC1=C(c2ccccc2)C2(OCc3ccccc3)CCCC2C1 +Cc1cccc(Cl)c1CNC(=O)c1cn2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc2n1 +O=C(C1CCOC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +Cc1cccc(CN2CCC(CCC(=O)c3ccc4c(c3)CCN4)CC2)c1 +Nc1cccc2c1CC(O)C(N1CCC(C(=O)c3ccc(F)cc3)CC1)C2 +COc1cc(F)ccc1-c1c(CN(C)Cc2ccccc2)[nH]c2c(NS(C)(=O)=O)cc(C(C)C)cc12 +Cn1cc(-c2ccc3nc(NC(=O)c4ccccc4)c(F)n3n2)c(-c2ccc(F)cc2)n1 +O=C(Oc1c(Br)cc(Br)cc1CNC(=O)c1ccccc1[N+](=O)[O-])c1ccccc1Cl +Cc1nnc(NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3-c3ccnn3C)c(C#N)c2)s1 +FC(F)(F)c1ccc2c(c1)c1cc[n+]2CCCCC[n+]2ccc(c3cc(C(F)(F)F)ccc32)NCCCCCN1 +O=C(O)c1cccc(C(CC(=O)c2ccc(Cl)cc2)CC(=O)c2ccc(Cl)cc2)c1 +C=CCC1(C)OC(S)=Nc2ccc(-c3cccc(Cl)c3)cc21 +O=C(O)C1CCN(c2cc3cccnc3c(-c3cccc(Cl)c3)n2)CC1 +CC1(C)CC=C(c2cc(C(C)(C)OCCN3CCCC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCCC3)n2)cn1 +N#Cc1c[nH]c(C(=O)Nc2ccc(-c3cc[n+]([O-])cc3)cc2C2=CCCCC2)n1 +Cc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)C)n1)CCN2 +COc1ccc2occ(CSC(=S)N3CCCCC3)c(=O)c2c1 +NCCOc1c(-c2ccc(F)cc2)[nH]c(=O)c2cc(F)ccc12 +Nc1ncccc1-c1nc2ccc(-c3ccccc3)nc2n1-c1ccc(CNC(=O)c2ccccc2)cc1 +N#CCCNC(=O)C1=CC(C(F)(F)F)(C(F)(F)F)Oc2ccc([N+](=O)[O-])cc21 +Cc1ccc(Cn2sc(=O)n(Cc3ccc(F)cc3)c2=O)cc1 +CCC(C)C(NC(=O)C(NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(C)C)C(=O)OC +COc1cc(-c2cn(C3CC(C(C)(C)C)CCN(CC(F)(F)F)C3=O)nn2)ccc1-n1cnc(C)c1 +CC(=O)N1CCC(c2nc3c(C(N)=O)cccc3[nH]2)CC1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1)C(=O)O +CC(CS)C(=O)N1C(SCc2ccc(C(C)C)cc2)CCC1C(=O)O +OC(CN1c2cccc(-c3cccc(OC(F)(F)F)c3)c2CCC1c1cccc(OC(F)(F)F)c1)C(F)(F)F +CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(S(C)(=O)=O)c3)ncn2)c1 +CC1(CC(=O)NCc2cccc(I)c2)CC2(CCCCC2)OO1 +O=Cc1ccn(-c2cc3c(cc2Cl)nc(O)n2nc(C(=O)O)cc32)c1 +Fc1ccc(-c2[nH]c(-c3ccc(F)cc3)c3c2CCCC3)cc1 +Cc1c(Oc2ccc(C#N)cc2F)ncnc1N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C 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+CC=CC=CC(=O)NC(CC(=O)NC(C(=O)C1C(=O)N(N(C)C)C(=O)C1C)C(C)C)c1ccccc1 +CC(C)C(CNO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +O=C(NCC1(N2CCOCC2)CCCCC1)c1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1 +Cc1ccc(NC(=O)Nc2ccc(S(=O)(=O)Nc3ccc(CC(C)(C)N)cc3)cc2)cc1 +CCCN(CCC)C1Cc2cc(F)c(O)cc2C1c1ccccc1 +COCCNC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CCCN1CCN(c2ccc3c(c2)C2CC3CCN2C(=O)OCc2ccccc2)CC1 +CNC(=O)c1nc(COC)ccc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +CCCN(CCC)CCc1ccc(O)c(OCCc2ccccc2)c1 +Cc1c(CCOCCO)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccccc1 +O=C(O)Cc1nn(CC(S)=Nc2cc(C(F)(F)F)ccc2Br)c(=O)c2ccccc12 +O=C1NC(=O)c2c1c1c3cc(F)ccc3[nH]c1c1c2c2cc(F)ccc2n1C1OC(CO)C(F)(F)C(O)C1O +CNC(=O)Cc1c(C)nc(CC(C)C)c(CN)c1-c1ccc(C)cc1 +CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CN(S(C)(=O)=O)CCN1C +C=Cc1ccc(-c2ccc(C(=O)NCC(C)(C)C)cc2C(=O)O)c(C(=O)Nc2ccc3c(N)nccc3c2)n1 +COc1ccccc1-n1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)nn1 +COc1ccc(-c2ssc(=S)c2-c2cc(OC)c(OC)c(OC)c2)cc1O +N#Cc1cc(NC(=O)NC2CCC(Oc3ccc(C(F)(F)F)cc3)CC2)cc(C(F)(F)F)c1 +Cc1ccc(C(=O)NCc2ccc(CNC(=O)C3CN(C)CCC3c3ccc(Cl)cc3)cc2)cc1 +Cc1c2ccnc(C(=O)NCCNCCO)c2cc2c3cc(O)ccc3n(C)c12 +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccncc3)sc12 +COc1cc(Br)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)OCCO)n1 +COc1ccc(-n2c(Cn3ccnc3)cc3ccc(Cl)cc32)cc1 +CCOc1ccc(C(Nc2ccc(C(=N)N)cc2)C(=O)NCc2ccccc2)cc1OCC +C#CC1(CO)OC(n2cc(I)c(=O)[nH]c2=O)CC1O +Cc1cc(Br)c(Oc2nc(Cl)nc(Nc3ccc(C#N)cc3)n2)c(Br)c1 +Cc1c(Cl)nc(Cl)nc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)N(CC)CC)c3ccc(Cl)cc3)CC2)c(F)c1 +O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)c1ccc(Cl)c(Cl)c1 +COc1ccc(NC(=S)N2N=C(c3ccc(O)cc3O)CC2c2ccc(O)cc2)cc1 +Cc1cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)cc(C)c1OCCNS(C)(=O)=O +Cc1ccc2nc(-c3ccccc3)c(NCc3ccccc3)n2c1 +COc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +NCCCCn1cc(-c2cccc(OCc3ccccc3)c2)c2c(N)ncnc21 +O=C(Cn1c(=O)n(-c2ccncn2)c2ccccc21)Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21 +CN(CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)CC(c1ccccc1)c1ccccc1 +Cc1ccc(CNC2=NC(=Cc3c[nH]c4ncccc34)C(=O)N2)cc1 +COCCN(CCOC)c1nc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCC3)[nH]c12 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5nccs5)cc4)cccc3c2F)CS1(=O)=O +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(N2CC(F)C2)CC1 +O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccccc5)CC4)cn3)nccc12 +O=S(=O)(c1ccccc1)N(Cc1ccc(OC(F)(F)F)cc1)c1sc2ccccc2c1Br +O=C1NCC(c2ccccc2)C12CCN(C1CCCCC1(O)c1cccc(F)c1)CC2 +CCC(=O)N1CCC(c2ccc(OCc3ccsc3-c3cccc(-n4ncc(C(=O)O)c4C(F)(F)F)n3)cc2)CC1 +COc1ccc(Nc2ncc(NCc3ccccc3)cc2-c2nc(C)nc3[nH]cnc23)cn1 +CCOC(O)=C1C(COCC(C)(O)c2ccco2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +COCCn1cc(-c2cccnc2)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O +CCCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)CC(C)O3)cc1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(Nc4ccc(NC5CCCNC5)nc4)c3c2)cc(Cl)c1O +CN1CCC2c3ccccc3-c3c(C4CCCCC4)c4ccc(C(=O)O)cc4n3CC21 +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(Cl)s1 +Cc1c(Nc2ccc(I)cc2F)c2c(=O)n(CC(O)CO)cnc2n(C)c1=O 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+O=C(O)c1cc(C2CC2)ccc1Nc1cnc(-c2cc(F)ccc2F)nc1 +CNC(=O)c1ccc(C(Cc2ccccc2)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)cc1 +CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NCc3ccccc3C)CC2)nc1C(F)(F)F +CCN(CC)CCCNC(=O)CCc1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)[nH]n3)n2)cc1 +O=C1C=C(Oc2ccc(F)cc2Br)C(=O)c2cc3ccccc3cc21 +Oc1cc(F)cc(-c2nc(N3CCOCC3)c3oc4ncccc4c3n2)c1 +Cc1c(C(=O)Nc2ccc(Cl)cc2)c2ccccn2c1C(=O)c1ccc([N+](=O)[O-])cc1 +CCC(=O)OC1c2c(cc(OC)c3c(=O)c4cc5ccccc5cc4n(C)c23)OC(C)(C)C1OC(=O)CC +C(#Cc1ccc(-c2ccc(OCCCN3CCCCC3)cc2)cc1)CN1CCCCC1 +CC1CCCN1C(=O)c1cc(Nc2ncc3cnn(C4CC5CC5C4)c3n2)cn1C +O=C(O)CCC=CCC1COC(c2ccc(OCCCCCCOc3cc(C(=O)O)ccc3OCCn3ccnc3)cc2)OC1c1ccccc1O +CC1(O)CN(c2nc(C(C)(c3ccc(-c4cnc(N)nc4)cc3)C3CC3)no2)C1 +CC(C)N1CCc2ccc(C#Cc3ccc4c(Cl)c(CN)sc4c3)cc2C1 +CC(C)c1c(C=CC(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)cn1-c1ccccc1 +CCCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +COc1cc(OCc2cccc(OCc3ccc(F)cc3Cl)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=c1[nH]c(N2CCOCC2)nc(NC2CCCNC2)c1-c1nc2cc(C(F)(F)F)ccc2s1 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+O=c1c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc2n1CC1CCCCC1 +N#Cc1ccc(Cn2cncc2CNC2CCN(C(=O)c3cncc(Br)c3)C2=O)cc1 +O=C(NC12CC3CC(CC(C3)C1)C2)NS(=O)(=O)c1cnccc1NC1CC2CCC1C2 +CCC(=O)NC(Cc1cccc(-c2nccs2)c1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1B(O)O +Nc1ccc(C(=O)NC(Cc2ccccc2)CC(O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)cc1O +CN(C)C(=O)CN1CCC(c2ccc(Nc3nc4c(-c5cnn(-c6ccc(F)cc6)c5)cccn4n3)cc2)CC1 +CC1CN(Cc2cn3cc(-c4cnc(N)nc4)nc(N4CCOCC4)c3n2)CCN1S(C)(=O)=O +COc1ccc(-c2ccc3c(c2)CC2CNCC3C2)cc1 +O=C(Cc1cccc(C(=O)NC2CCCc3cc(CN4CCCCC4)ccc32)c1)c1ccccc1 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCn3ccc4ccc(Cl)nc43)c2)c1 +Cc1cccc(CNCC(C)C(=O)N(Cc2cc(Cl)c3c(c2)CCCCO3)CC(C)C)c1C +COc1cccc(CNC(=O)Nc2ccc(C3=NC=NC4NC=CC34)cc2)c1 +CCC1(c2cccc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCOCC1 +Fc1ccc(Cn2c(C3CCCN(Cc4ncco4)C3)nc3ccccc32)cc1 +O=C(NCCCCCCCCCCNC(=O)Nc1ccc(C2=NCCCN2)cc1)Nc1ccc(C2=NCCCN2)cc1 +O=C(NC1CNC1=O)OCc1ccc(C2CCCCC2)cc1 +COc1ccc(C(=O)C=Cc2ccc(C(=O)O)cc2)cc1[N+](=O)[O-] 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+O=C(CCCCc1cn(Cc2ccc(F)c(Cl)c2)nn1)NO +Cc1ccc(CCC(=O)Nc2ncc(Cc3cccc(Cl)c3Cl)s2)o1 +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc(OCCCn4cccc4)c4[nH]nc(N)c34)cc2)c1 +CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1ccc(OC)cc1 +CC(OCC1(c2ccccc2)CC(N)(C(=O)N(C)C)C1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCC(O)(c1ccccc1)N1CCC(NC(=O)c2cccc3ccccc23)CC1 +O=C(O)COc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)NCCCCC2CCCCC2)co1 +CCC(CC)OC1C=C(C(=O)Nc2ccccc2OC)CC(NC(=O)OC(C)(C)C)C1NC(C)=O +CC(c1cccc2ccccc12)C(CS)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +Cc1nn(C(F)F)cc1-c1cnc(N)c(-c2ccc(C(=O)NC(CO)c3cccc(CF)c3)c(F)c2)c1 +COC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC(CN)CN)c2c1C +O=C(Nc1ccc(O)c(Cl)c1)C1CCN(CC(=O)N2CCN(c3nc4ccccc4s3)CC2)C1 +Nc1ncnn2c(C3CCC(CNCCO)CC3)nc(-c3ccc(Oc4ccccc4)cc3)c12 +COc1c(-c2cnn(C)c2)ccc2cnc(Nc3ccc(-n4cnc(N5CCOCC5)n4)cc3)nc12 +CCOC(=O)N1CCC(N2CCC2C(=O)N2CC(Sc3cccc(C(F)(F)F)c3)CC2C(=O)NC2(C#N)CC2)CC1 +O=C(NCC(CC1(C(F)(F)F)CC1)c1ccc(C(F)(F)F)nc1)c1ccccc1Cl +O=C(Nc1ccnc(O)c1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COc1ccc(C2(C#N)CC3CC(C(=O)NO)CC3C2)cc1OC(C)C +NC(=O)c1ccc(CCc2c(C(=O)O)[nH]c(=O)[nH]c2=O)cc1 +C=CC(=O)Nc1cc(Nc2n[nH]c3ccc(-c4ccc5ccccc5c4)cc23)c(OC)cc1N(C)CCN(C)C +OCC1OC(c2ccc(Cl)c(Cc3ccc(OC4CCOC4)cc3)c2)C(O)C(O)C1O +CC(c1ccccc1)c1nc(-c2cnc(N)c(-n3nnc4ccccc43)n2)nn1C +O=C(Cc1ccc(-c2ccccc2)cc1)NCc1ccccc1 +O=C1C2CC(O)(COCC(F)(F)F)CC2CN1c1ccc(OC(F)(F)F)cc1 +COCCNC(CN1CCC2(CC1)CCN(C1=C(C)C(=O)OC1)C2=O)c1ccc2c(c1C)COC2=O +O=C(Nc1ccc2nc(C3CC3)cn2c1)c1ccc(-c2ccccn2)cc1 +O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2cnn1CC(F)(F)F +CCc1cc2cc(-c3c(Cl)nc(N)nc3NC3CC(CO)C(O)C3O)oc2c(CC)n1 +Cc1nc(N2CCC(N3CCCC3=O)CC2)nc2ccc(NC(=O)C=Cc3ccc(Cl)cc3)cc12 +COC(=O)c1ccc(CSc2nc(Cc3c(F)cccc3F)c(C)c(=O)[nH]2)cc1 +Brc1cccc(C=NNc2nc3ccccc3nc2Cc2ccccc2)c1 +Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc([N+](=O)[O-])cc3)ccc2n1 +O=C(Nc1cc(-c2ccccc2)ccc1N1CCNCC1)c1cc2ccccc2oc1=O +CCCC(=O)Nc1n[nH]c2c(F)c(Cl)c(-c3ccccc3)cc12 +CCNc1nc2c(C)c(C)c(O)c(Cc3cccnc3)c2s1 +COC1C=CC(C)C2OC(O)(C(C)C(=O)OC(c3ccccc3)CCCCC1OC)C(OC)C(O)C2C +O=C1c2c(ccc3ccccc23)CN1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1 +O=C(Cc1cc(Br)cc(Br)c1OCc1c(Cl)cccc1Cl)Nc1ccccc1[N+](=O)[O-] +CCn1c2cc(Cl)c(O)cc2c(=O)c2c(=O)o[nH]c21 +CCCCC1(CC)CS(=O)(=O)c2cc(CNC(CCS(C)(=O)=O)C(=O)O)c(OC)cc2C(c2ccccc2)N1 +COc1cc(C(=O)NC2CCN(C)CC2OC)c(F)cc1Nc1ncc(Cl)c(Oc2cccc3c2C(=O)N(C)C3C)n1 +c1ccc2c(NC3CCCCCC3)nc(N3CCC(N4CCCC4)CC3)nc2c1 +NC(=O)c1ccc(-c2ccc(Cl)cc2COc2ccc(-c3nc4cc(C(=O)O)ccc4n3C3CCCCC3)cc2)cc1 +COc1n[nH]c2cc(NC(=O)NCc3c(F)cccc3Cl)ncc12 +CCNC(=O)C1OC(n2cnc3c(NCC)nc(C#CC(O)C4CCCC4)nc32)C(O)C1O +O=C(NC1CCOCC1C(=O)NO)c1ccc(Cc2c(C3CC3)nc3ccccn23)cc1 +COc1ccc(-c2ccc(Cl)c(C(=O)NCC3(O)CCCCCC3)c2)nc1 +O=C(c1ccc(Oc2nccnc2N2CCC(O)CC2)cc1)c1nc2ccccc2[nH]1 +COc1ccc(-n2nc(CCC(=O)N(C)O)cc2-c2ccc(Cl)cc2)cc1 +COc1ccc(C(=O)NC2N=C(c3ccccc3)c3cc(C)cc4c3N(CC4)C2=O)c(OC)c1 +COc1ccc(S(=O)(=O)N(CC(=O)NO)OCc2ccc(Cl)cc2)cc1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)NCC3CNC(=O)C3)[nH]c12 +Cn1c(=O)c2cc(Cl)ccc2n2cnc(C(=O)OC(C)(C)C)c12 +NC(=O)C12CC3CC(C1)C(NC(=O)c1cccc(NS(=O)(=O)c4cccc(F)c4)c1)C(C3)C2 +O=C(c1nccs1)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(-c5cn(C)cn5)sc34)c(F)c2)cnn1-c1ccccc1 +CC(=O)N(O)CCC(n1cc(C(C)(C)C)nn1)P(=O)(O)O +N#Cc1cnc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)cn1 +CC(OC1CCC2NC1(c1ccccc1)CC2(F)c1nnn(C)n1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCc1cc(-c2noc(-c3ccc(CC(C)C)c(C)n3)n2)cc(C)c1OCC(O)CNC(=O)CO +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(CN5CCC(O)C5)cc4)c3)c(OCCCF)cc21 +COCCOCC(=O)N1CCC(CCCCNC(=O)N2Cc3ccncc3C2)CC1 +CC(=O)OC(CC1CCCC(CC(=O)c2ccccc2)N1C)c1ccccc1 +CC1CN(C(=O)c2cc3c(C(=O)C(=O)N(C)C)cn(C)c3cc2Cl)C(C)CN1Cc1ccc(F)cc1 +N#Cc1cccc(C23CCC(N(CCN4CCC(O)C4)C(=O)Nc4ccc(F)c(Cl)c4)CC2C3)c1 +O=C(O)Cc1nn(Cc2nc3cccc(C(F)(F)F)c3s2)c(=O)c2ccccc12 +CC1(C)C2CCC1(CS(=O)(=O)Nc1cccc(S(N)(=O)=O)c1)C(=O)C2 +COC1(C(F)(F)F)CC(c2nc(-c3ccc(C)c(N(C)C(=O)c4cnc5ccccn45)c3)no2)C1 +O=C(Nc1ccncn1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +Cn1c(C2CCCCO2)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O +COCCN1CCC(Nc2nc(-c3nc4ccccc4n3Cc3ccc(F)c(F)c3)cn3c(C)nnc23)CC1 +O=C(CN1C(=O)Cc2c([nH]c3ccc(Br)cc23)-c2ccc(Cl)cc21)NCc1ccc(O)cc1 +CCCCNc1ncc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)c(NC2CCC(O)CC2)n1 +Cn1nc(CC(=O)Nc2ccc3oc4ccccc4c3c2)c2ccccc2c1=O +O=C(Nc1ccc(C(F)(F)F)cc1)N1Cc2ccccc2C1 +COc1cc(Sc2c[nH]c3ccc(OCCO)cc23)cc(OC)c1OC +CC(C)(C)NCC(O)CON=C1CC2CCC1(C)C2(C)C +CCC(C)(C)C(=O)C(=O)N1CCCC1C(=O)SCCCc1ccccc1 +Oc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1CN1CCCCC1 +Cc1cc[n+](CCCCCCCC[n+]2ccc(C)cc2N)c(N)c1 +CCCCCCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(O)c2c1=O +COc1ccc(CCCN2CC=C(CCC(=O)NO)C2=O)cc1 +CCC(C)n1c2cnccc2c2cnc(Nc3ccc(N4CCNC(C)(C)C4)nn3)nc21 +Cc1ccc2nc(-c3ccc(OCc4ccccc4)cc3)c(NC3CCCCC3)n2c1 +CCCn1c(=O)c2nc(C34CCC(C=CC(=O)O)(CC3)CC4)[nH]c2n(CCC)c1=O +C=C1C(=O)OC2OC3(C)CCC4C(C)CCC1C24OO3 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCC(CO)C2)c(-c2cncc(F)c2)c1 +CCOC(=O)c1cn2ncnc(Nc3cc(C(=O)NOC)c(F)cc3F)c2c1C(C)C +OCc1cccc(-c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)c1 +COc1ccc2c(n1)CN(c1ncnn3c(C)nc(C4CCOC4)c13)CC2 +O=C(NCc1cccc(-c2ccc(F)c(CN3CCNCC3)c2)c1)c1ccc2c(c1)OCO2 +c1ccc(COCCCOc2ccc(C3CCNCC3OCc3ccc4ccccc4c3)cc2)cc1 +CCNC(=O)Nc1cccc(-c2cnc3cc(-c4ccnc(C(F)(F)F)n4)ccn23)c1 +Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(c3cccc(C(C)C)c3)C(C)C)cc12 +O=C(O)CCCCOc1cc(Cl)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +O=C1CCC(CCN2CC(N3CCNCC3)C2)(c2ccc(Cl)c(Cl)c2)CN1Cc1ccccc1 +O=S(=O)(c1cccs1)N1Cc2ccccc2N(Cc2c[nH]cn2)C(CCc2ccccc2)C1 +CCN(CC)Cc1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +O=C(CN1C(COc2ccccc2)C(O)C(O)C(COc2ccccc2)N(Cc2ccccc2)S1(=O)=O)Nc1nccs1 +COc1ccc(Nc2ccc3c(c2)C(=CNc2ccc(CN4CCCCC4)cc2)C(=O)NC3=O)cc1 +COc1ccc(NC(=O)Nc2cc(S(=O)(=O)N3CCCCC3)oc2C)cc1 +CC(NCC(O)c1ccc(O)c2[nH]c(=O)sc12)c1ccc2ccccc2c1 +COC1CCC(Nc2ccn3ncc(-c4cccc(OC(F)(F)F)c4)c3n2)CC1 +Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(F)c4Cl)cc3)cnc12 +CCOC(=O)N1CCN(CCCOc2ccc(C(=O)c3cccc(F)c3F)cc2)CC1 +CN1CCN(Cc2ccc(C(=O)NN(CC3CC=CC3)c3nc(C#N)ncc3Br)cc2)CC1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCC4CN(C)CCO4)ncc23)ccn1 +COc1cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5cc(C)ncn5)ccc43)cc2F)ccc1F +C1=C(c2ccccc2)CCN(CCCCc2c[nH]c3ccccc23)C1 +Cc1ccccc1N1CCOc2cnc(NC3CCN(c4ccnc(Cl)c4)CC3)nc21 +Cc1cc(-c2nc(-c3ccc(OC4CC4)c(C)c3)n3c2CCOC(C)C3)cc(CF)n1 +NC(=O)C(Cc1ccccc1)NC(=O)CCCCCCC(=O)NO +NC(=O)c1cc2c(Oc3ccc(C(=O)N4CCOCC4)cc3)cncc2s1 +CCCCCN1CC2N(C(=O)OCCc3ccc(O)cc3)CCC(=O)N2C(Cc2ccccc2)C1=O +CCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 +CCc1ccc(OCCOCCOCCCCCNC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 +CCNC(=O)OCc1c(COC(=O)NCC)c(-c2ccc(F)c(F)c2)n2c1Cc1ccccc1C2 +O=c1nc(OCC2COCCO2)cc2n1CCc1cc(COC3CCCC3)ccc1-2 +CC1(c2ccc(C(=N)N)cc2)NC(=O)N(CC(=O)NC(CC(=O)O)C(=O)NC(C(=O)O)c2ccccc2)C1=O +Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCc1ccccn1 +CCCCc1ncc(C(=O)O)n1Cc1ccc(-c2ccccc2-n2cnnn2)cc1 +COCCN(CC1CC1)c1nc(C)nc2c(-c3ccc(OC)nc3C)c(C)nn12 +CCCc1cc(=O)oc2cc(OCCCCN3CCC(c4noc5cc(F)ccc45)CC3)ccc12 +COc1cc(C(C)=O)ccc1OCCCN1CCC(C(c2cccc(F)c2)c2cccc(F)c2)CC1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCC2CCN(CC3CCOCC3)CC2)CCCC1)c1cc2ccccc2s1 +CCC(NC(=O)c1cc(C(=O)NCc2ncccn2)n2c1COCC2)c1ccccc1 +Cc1ccc(NC(=O)c2cc(NC(=O)c3cc(Cl)ccc3Cl)cc3[nH]c(N(C)C)nc23)cc1Cl +O=C(Nc1ccc2c(c1)C=CS(=O)(=O)O2)c1ccncc1 +CC(C)(O)CC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +COC1Oc2cc(F)ccc2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +COCCOc1cc2c(cc1OC)Nc1ncnc(Nc3cc(OC)c(Cl)cc3Cl)c1C2 +O=S(=O)(c1ccccc1)N1N=C(c2ccccc2O)CC1c1ccc(O)cc1 +O=C(C=Cc1cnccc1-c1cnn(CC(F)(F)F)c1)Nc1ccc(CN2CCOCC2)cc1 +CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(C(F)(F)F)o4)c(C(C)C)c23)c(F)cc1F +CC(C)CCCC(C)C1CCC2C3C(O)C=C4CC(O)CCC4(C)C3CCC12C +CCN(CC)C(=O)c1ccc(C(c2ccccc2)C2CCNCC2)cc1 +COc1c(C)cc(-c2c(-c3cccc(OC(F)(F)F)c3)cc3n2C(CCN)CNC3=O)cc1C +CCCc1cc2c(C(F)(F)F)cc(=O)[nH]c2cc1N +O=c1c(O)c(-c2ncc(Cc3ccc(F)cc3)[nH]2)nc2c(Br)cc(N3CCOCC3)cn12 +C=CCNC(=S)N1CCc2c([nH]c3ccccc23)C1C(F)(F)F +O=C(NCc1ccc(F)cc1)C1C(=O)N(O)C(=O)c2cc(F)ccc21 +CN(c1ccc(NC(=O)Nc2cccc(C(F)(F)F)c2)c(F)c1)c1cc(NC(=O)C2CC2)ncn1 +Cn1c(OCCOc2ccccc2)nc(-c2ccncc2)cc1=O +CCOc1c(F)cccc1C1CC(F)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +CC(=O)C1CCC2C3CCC4CC(O)(C#Cc5ccc(-c6ccccc6)cc5)CCC4(C)C3CCC12C 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+O=C(NCc1cccc(Cl)c1)Nc1cc(-c2ccccn2)n[nH]1 +CCCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1 +CCOC(=O)c1ccc(Oc2c[nH]nc2-c2ccc(OCC(=O)NN)cc2O)cc1 +CC(CCC(=O)O)(NC(=O)c1ccc(CCC2CNc3nc(N)nc(N)c3C2)cc1)C(=O)O +NC(=O)C1=c2ncnc(NCc3cccc(NC(=O)c4ccc(C(F)(F)F)cc4)c3)c2=CCC1 +c1ccc(COCCOCc2ccc(C3CCNCC3OCc3ccc4ccccc4c3)cc2)cc1 +CCCNC(=O)c1cnc(Nc2ccc(C#N)cc2)cc1Oc1c(C)cc(C)cc1C +CN(C)C(=Nc1cccc(C(=CCCCC(=O)O)c2cccnc2)c1)NC#N +Cc1ncnc(-c2ccc(C(=O)N3CCCO3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +O=C(NC(CC1CC1)c1nccs1)c1ccc(C2CCOCC2)c(OCC2CC2)n1 +N#Cc1ccc(OC(c2ccc(F)cc2)C2CCCNC2)cc1 +O=C(CCCCCCc1ccccc1)c1ncc(-c2ccccc2)o1 +NC(=O)C[S+]([O-])C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 +CS(=O)(=O)c1ccc(C2=CC(=O)c3ccccc3S2(=O)=O)cc1 +CSc1ccc(-c2sc(N)nc2-c2ccc(P(=O)(O)O)o2)cc1 +COCCOc1cc(NC(=O)N2c3nc(C=O)c(CN4CCN(C)CC4=O)cc3CCC2C)ncc1C#N +CC(Oc1ccccc1-c1cccc([N+](=O)[O-])c1)C1=NCCN1 +Cc1cccc(-n2cc3c(n2)c(N(C(=O)c2ccccc2)C(=O)c2ccccc2)nc2ccccc23)c1 +O=[N+]([O-])c1cccc(-c2ccccc2CCC2=NCCN2)c1 +O=C(c1ccn2c1CSC2c1cccnc1)c1c[nH]c2cccc(O)c12 +CN(c1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O)C1CCCCC1 +CCC1(CC)CC(NC(=O)Nc2ccc3c(c2)N(C)C(=O)CC3)c2ccc(Cl)c(Cl)c2O1 +CCc1cccc(CC)c1NC(=O)CC(N)C(Cc1ccccc1)NC(=O)C(NC(=O)CCCc1ccccc1)C(C)C +CCCC(O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CCN)CC1 +CN1Cc2c(C3=CC4CNCC4C3)[nH]c3nccc(c23)-c2cc(F)ccc21 +COc1ccc(CCNCC(O)COc2cccc3[nH]ccc23)cc1OC +COC(=O)c1c(F)cccc1-c1ccc(CNc2ccc(C(=O)N3CCN(CC4CC4)CC3)cn2)c(F)c1 +O=C(NCC1CCNCC1)c1ccc(Cl)cc1-c1cccc(Cl)c1 +CC(c1nc2ccccc2o1)n1cc(C=CC(=O)NO)nn1 +Cc1nn(C)c2ncc(C(=O)NO)c(N(C)S(=O)(=O)c3ccc(Oc4ccc(Cl)cc4)cc3)c12 +Cc1nc(-c2ccc3occ(-c4ccc([S+](C)[O-])cc4)c3c2)no1 +Cc1nnc2c(NC(C)C)nc(-c3nc4ccccc4n3Cc3ccccn3)cn12 +Cc1nc(NCC(F)(F)F)nc(NC2CC(CO)C(O)C2O)c1-c1nc2cnccc2s1 +CNC(=O)N1CC=C(c2cc3c(-c4cc(F)c(F)cc4OC)ccnc3[nH]2)CC1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NCc1nnnn1C +Cn1cnc2ccc(-c3cc(NCC(O)CN4CCc5ccccc5C4)ncn3)cc21 +O=c1c2c(oc(O)c1C(c1cccc(NS(=O)(=O)c3cccc(Cl)c3)c1)C1CC1)CCCCCC2 +OCC(NC1CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1)c1ccccc1 +CC(C)n1ncc2c(C(=O)Nc3ccc(F)c(S(N)(=O)=O)c3)cc(-c3cccs3)nc21 +Cc1cc(C(=O)O)nn1Cc1ccccc1OCc1ccc(Cl)cc1Cl +CCCCCCCc1ccc(C(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +NC1CN(Cc2ccc(-n3cnnn3)cc2)CC1C(=O)N1CCCC1 +COc1ccc(N=C2c3cccc(Cl)c3C(=O)c3c(Cl)cccc32)cc1O +COC(=O)C=CC(=O)NC1CC23CCC1(OC)C1Oc4c(O)ccc5c4C12CCN(CC1CC1)C3C5 +O=C(c1ccccc1)N1CCC2(CCCN(c3ncc(-c4ccccc4)c(-c4ccc(Cl)cc4)n3)C2)CC1 +COCC(C)Oc1cc(C#Cc2ccc3[nH]ccc3c2)cc(C(=O)Nc2ccn(C)n2)c1 +Cn1c(SCc2ccccc2)nc(-c2ccccc2)c1-c1ccccc1 +Cc1ccc(C(=O)NC2CCC(CCN3CCC(c4cccc5c4CCO5)CC3)CC2)cn1 +FC(F)(F)c1nc(N2CCCCC2)c2[nH]c(-c3ccccc3)cc2n1 +COc1nc(NCCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +CN(CCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N)CC2)S(=O)(=O)CC1CC1 +CCOc1ccc2cc(-c3nn(CC4CCN(S(C)(=O)=O)CC4)c4ncnc(N)c34)ccc2c1 +Cc1cc(C#N)cc(Cl)c1Oc1nc(NC2CCN(c3cccc(C(N)=O)c3)CC2)ncc1Br +CC1=C(CCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)c2ccccc2C1=O +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1Nc1ccc(CN2CCCC2)cc1 +c1ccc(CCCN2CCC3(CC2)OCc2ccccc23)cc1 +O=C(NCCOCc1ccccc1)n1c(=O)oc2ccccc21 +O=C1CCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(Cc2ccccc2)C(=O)NC(CCc2ccccc2)CN1 +COc1cccc2cc(C(=O)C=Cc3cc[n+](Cc4ccccc4Cl)cc3)c(=O)oc12 +Nc1ccc(C#CCCN2CC=C(c3ccccc3)CC2)cn1 +c1ccc(N2CCN(CC3CCC(Nc4ncccn4)CC3)CC2)cc1 +CC(C)(C)CC(=O)Nc1ccc2c(c1)cc(C(=O)Nc1ccccc1)n2Cc1ccccc1C(F)(F)F +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC2CCC2)C(=O)C(O)CO)c1 +COC12CCC3(CC1C(O)CCC(C)C)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CN1C2CCC1CC(OC(c1ccc(Br)cc1)c1ccc(Br)cc1)C2 +CC(NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CC(C)CC(NC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +COc1ccc(CC2Cc3c(ccc(O)c3O)C(CN)O2)cc1 +Cc1cn(Cc2ccccc2)cc1C(=O)NCc1c(C)cc(N)nc1C +CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2ccc(OC)nc2)c1 +Cc1cc(C)cc(-c2[nH]c3ccc(C(=O)N(C)C)cc3c2CCNCCCCc2ccncc2)c1 +CN(C)CCn1ccc2c1C(=O)c1cnccc1C2=NOCCO +Cc1cn(C2CC(N=[N+]=[N-])C(CO)O2)c(=O)n(CC2CC(CO)=NO2)c1=O +COC1Cc2sccc2C2(CCN(CCCCc3ccccc3)CC2)O1 +O=C(Cc1ccccc1)NC1CCN(C(c2cnccn2)c2ccc(F)cc2F)CC1 +CC1CC2CSC(N)=NC2(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CO1 +O=C(CNC12CC3CC(CC(C3)C1)C2)N1CCCC1B(O)O +COc1cc2c(c3c1c(=O)c1ccccc1n3C)CC(C1(C)CO1)O2 +CCOc1ccccc1-c1nc(O)c2nc3ccc(Br)c(C)n3c2n1 +Cc1ccc(C(=O)N2CC(C)OCC2Cc2cc(-c3ncccn3)ccc2F)c(-n2nccn2)c1C +Cc1ccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)cc1S(=O)(=O)N1CCOCC1 +c1ccc(CN2CCN(c3nc4ccccc4s3)CC2)cc1 +Cc1cc(OCCCON=C(N)N)cc(OS(=O)(=O)c2ccccc2S(C)(=O)=O)c1 +COc1ccc2nc3cc(Cl)ccc3c(Nc3ccc(N4CCCCC4)cc3)c2c1 +Cc1c(Cl)cccc1-n1nnnc1SCC(=O)Nc1ccccc1[N+](=O)[O-] +Nc1nc(-c2ccc(OCC3CCOC3)c(OC(F)(F)F)c2)c(Cl)c(=O)[nH]1 +CC(C)c1ccccc1-c1nc(NCc2ccc(-c3cccnc3)cc2)c2cccn2n1 +CC(C)(F)c1nccn1CC1CC(c2ccccc2)(c2ccccc2)C(=O)O1 +CCCCc1ncc(C(=O)OCC)c(NCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)n1 +CCOP(=O)(OCC)C(=O)OCC1OC(n2ccc(NC(C)=O)nc2=O)CS1 +CCNc1cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CCc3ccccc32)cc(N2CCCCS2(=O)=O)c1 +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)Nc3cccc(C(=O)O)c3)cc12 +Cn1c(=O)c2ccc(-c3cccnc3)cc2n2nc(-c3ccccc3)cc12 +NC(=O)c1ccc2c(c1)CCCN2c1ccc(CNC2Cc3ccc(F)cc3C2)cc1 +CCN(CCO)c1ncc(C(=O)Nc2ccc(SC(F)(F)F)cc2)cc1-c1cncc(F)c1 +COc1cc(NC(=O)C=Cc2cccnc2)ccc1-c1cnco1 +Cc1cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)cc(C)c1OCC(CO)CO +CN(Cc1nc2ccccc2n1CCC1CCCCN1)C1CCCc2cccnc21 +CC#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C +N#Cc1ccc(C(c2cccnc2)N2CCC(NC(=O)c3nccs3)CC2)cc1 +COc1ccc(CNC(=O)c2nn(-c3ccc(F)cc3)c(OCC(O)CC(O)CC(=O)O)c2C(C)C)cc1 +C(COc1ccc(Cc2ccccc2)cc1)=NOC1CCCC1 +CCCCCCNC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1C +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(SC)nc4)cc23)c1F +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(N4CCCC5(CCC(C(=O)NO)CC5)C4)ccc3OCC)nc12 +Cc1oc(-c2cccc(Br)c2)nc1CN(Cc1ccccc1)Cc1ccc(OC(C)(C)C(=O)O)cc1 +CCC(=C(c1ccccc1)c1ccc(O)cc1)c1ccccc1 +COc1ccc(-c2ccc(OCCCCN3CCc4cc(OC)c(OC)cc4C3)cc2)cc1 +CNC(=O)c1ccc(-n2cnc3c(NCC4CCOCC4)cc(Oc4ccc(O)c(F)c4)cc32)cc1C +CCN(CC)Cc1cc(Nc2cccc(C(=O)NC(Cc3ccccc3)C(O)CNC3CCCC3)c2)ccc1O +CC1(c2cc(NC(=O)c3ccc(Cl)cc3)ccc2F)CS(=O)(=O)C2(CCOC2)C(=N)N1 +COc1ccc2c(c1)C1C(CCN1CCN(C)C)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCc3ccc(CC(C)C)cc3F)ccc21 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)O)cc3O)[nH]c2n(CCC)c1=O +NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3cccc(OC(F)(F)F)c3F)c2)n1 +CNC(C)C(=O)NC(C(=O)N1c2ncccc2CC1CNS(C)(=O)=O)C(C)C +COc1ccc(F)c(-c2ccc(COc3cccc(C(CC(=O)O)C4CC4)c3)cc2C2=CCCC2(C)C)c1 +CCC(C)OC(=O)CCC(=O)Nc1nnc(S(N)(=O)=O)s1 +CC1SC(N)=NC2(c3ccc(F)cc3F)COC(c3ncco3)CC12 +CCCCCCCCCCCCOc1c(OC)cc(Nc2c(C#N)cnc3cc(OC)c(OC)cc23)cc1OC +Cc1c(-c2ccc(F)cc2)c(C=CC(O)CC(O)CC(=O)O)c(C(C)C)n1-c1ccccc1 +CC(C)c1onc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +CCc1ccc(N=C2NC(=O)C(=Cc3ccncc3)S2)cc1 +CN(C)CCn1nc2c3c(c(N(C)C)ccc31)C(=O)c1ccncc1-2 +Nc1nc(Nc2cccc(C(=O)O)c2)nn1C(=O)c1c(F)cccc1F +CCC1OC(c2ccc(Cl)c(Cc3ncc(-c4ccsc4)cn3)c2)C(O)C(O)C1O +C=CCN(CC=C)c1ccc(C=C(C#N)C(=O)O)c(OC)c1 +O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(c2[nH]cnc3ncnc2-3)CC1 +CN(C(=O)c1ccccc1)c1nc(-c2ccc(Br)cc2)cs1 +Clc1cccc(Nc2nccc(-n3cnc4ccccc43)n2)c1 +COc1ccc(C2c3[nH]c4ccccc4c3CC3C(=O)N(Cc4ccccc4)CN32)cc1 +CC1(C)OCc2c(Nc3n[nH]c(Cl)c3Cl)nc(-c3cn[nH]c3)nc21 +NC(=O)C1(NC(=O)c2cnc(N3CC(F)(F)C3)c(OCC3CC3)n2)CCCCC1 +CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)c1ccc(N2CCCC2=O)cc1 +O=C(COc1ccc(C=NNC(=O)c2ccc(O)c(Cl)c2)c2ccccc12)Nc1ccc(Cl)cc1 +CC(C)(C)c1ccc(C(=O)Nc2ccc3sc(CN)nc3c2)cc1 +C#CCNC(=O)c1ccccc1Nc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 +CN1CCN(C(=O)CCCOc2cc(C(=O)N3CCCCc4sccc43)ccc2NC(=O)c2ccccc2-c2ccccc2)CC1 +CCN(CC)C(C)C(c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC2(c3ccccc3)CC2)c1 +COc1ccc(-c2cccc(-c3ccc(O)cc3)n2)cc1OC +CN1CCN(c2ccc(C(=O)Nc3sc(Nc4ccc5ncccc5c4)nc3C(N)=O)cc2)CC1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc([N+](=O)[O-])cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2ncoc2c1 +CCN(CC)CCOc1ccc(-n2c3c(c4ccc(O)cc4c2=O)C(=O)c2cc(O)ccc2-3)cc1 +COc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CN(C)CCO1 +COc1cc2c(cc1OC)-c1c(-c3cnc(CN4CCCOCC4)s3)ncn1CC2 +O=C1C(=O)N(Cc2ccnc(F)c2)c2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc21 +CN(C)CCn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2Br)CC1 +CCNC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3c(n2)C(C)(C)OC3=O)cc1 +Cc1c(C(=O)N(C)C2(C#N)CCOCC2)nn(-c2ccccc2Cl)c1-c1ccccc1 +CN1CCN(C(=O)c2cccc(Nc3c(Nc4ccccc4)c(=O)c3=O)c2O)CC1 +CN(C)S(=O)(=O)c1cccc(N2CCC(N(c3ccc(C#N)cc3)c3cccnc3)CC2)c1 +Cc1cccc(C)c1N1CC(CN2CCC(F)(F)C2)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)C(C)C1=O +O=S(=O)(c1ccc(Cl)s1)n1cc(C2CCCNC2)c2ccccc21 +COc1ccccc1Nc1nc(Nc2ccc(O)cc2)ncc1F +CNc1nc2c(N)ncnc2n1C1OC(COCc2ccccc2)C(O)C1O +Nc1ccc2c(c1)c(OCc1ccc3ccccc3c1)nn2CCN1CCCCC1 +CC1CN(CCCn2c3ccccc3c3ccccc32)CC(C)N1 +COc1ccc(CN2C(C(Cc3c[nH]c4ccccc34)NC(=O)C3CCCCC3)=NNC2CCc2ccccc2)cc1 +NC1(c2ccc(-c3nc4c(-c5cccc(F)c5)cccn4c3-c3ccccc3)cc2)CCC1 +Oc1ccc(-c2cnc3[nH]cc(-c4ccc(-c5nnn[nH]5)cc4)c3c2)cc1 +COc1ccc(N2CCN(CCCCc3c[nH]c4ccc(OC)cc34)CC2)cc1 +CCCCCCCCCCCCC(O)C1CCC(C(O)CCCCCCCCCCCCC2=CC(C)OC2=O)O1 +CC1(C)C2CC=C(CN3CCC(Nc4nc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)ns4)CC3)C1C2 +O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cc(F)ccc3F)s2)nn1 +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1scnc1C(=O)O +O=C1C(=O)c2cc([N+](=O)[O-])ccc2-c2ccccc21 +Cc1ncoc1-c1nnc(SCCCN2CCC3CC3(c3ccc(C(F)(F)F)cc3)CC2)n1C +NS(=O)(=O)c1ccc(NC(=O)c2c(-c3ccc(Cl)cc3Cl)noc2NC(=O)c2ccccc2)cc1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc(-c3ccccc3)cc2)nn1 +COc1cc(-c2ccc(OC(F)(F)F)cc2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +O=C(CS(=O)(=O)c1ccccc1)c1ccc(F)cc1 +Cn1cc(NC(=O)c2cc(NC(=O)c3cc(NC(=O)c4sccc4Cl)cn3C)cn2C)cc1C(=O)NCCCN1CCCCC1 +COC1C(F)CN(C(=O)Cn2nc(C(N)=O)c3ccncc32)C1C(=O)NC(C)c1cccc(Cl)c1F +Cc1cc(-c2ccc(N3C(=O)c4n[nH]c(C(C)(C)C)c4C3c3ccccc3OCCO)cc2)on1 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCC2CCCC3(C2)OCCO3)cc1F +Brc1c(Br)c(Br)c2[nH]c(NC3CCCNCC3)nc2c1Br +Cc1cccc(N2CCN(CCCNC(=O)c3cc(-c4ccccc4)n(N4CCCCC4)c3C)CC2)c1C +Cc1cc(NCC(N)c2ccncc2)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +CC1CCN(CCC2CCCN2S(=O)(=O)c2ccc3[nH]cnc3c2)CC1 +COc1ccc(OCCN(C)CCCN2C(=O)CSC2c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1 +Cc1cc(-c2ccc(CNC(=O)c3ccc4c(c3)C(F)(F)c3ccccc3-4)cc2)ccn1 +CN1CC=C(c2cn(C(=O)c3ccccc3)c3ccccc23)CC1 +O=C(Nc1ccc(-n2ncc3c(C(F)(F)F)cccc32)cc1)Nc1ccc(C(F)(F)F)cc1 +CCOc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCN(C(=O)OCC(C)C)CC3)s2)cc1 +COc1cc(C=Cc2ccc(-n3[se]c4cc(Cl)ccc4c3=O)cc2)cc(OC)c1 +Cc1cc(C(=O)Nc2ncc(-c3ccccc3S(N)(=O)=O)cn2)n(-c2ccc3cc(Cl)ccc3c2)n1 +CN(C)CCCn1cc(C2=C(c3csc4ccccc34)C(=O)NC2=O)c2ccccc21 +N#Cc1c2c3ccc(N4CCSCC4)c4cccc(c-2nc1=O)c43 +NC(=O)Cc1ccc2c(O)cc(-c3ccccc3)nc2n1 +COc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(N(C)C)c3ccccc32)cc1 +Cc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)O)cc3Cl)nc1-2 +CCCCCCCN(C)c1ccc(C(=O)Nc2cnc3ccccc3c2)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccno4)ncc23)ccn1 +CC(C)C(NC(=O)OCc1ccc(F)c(F)c1)C(=O)NC(CC(=O)O)C(=O)CF +COc1cc(F)ccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 +COc1n[nH]c2cc(NC(=O)NC(CO)c3ccccc3)nc(C)c12 +N#Cc1cc(-c2ccc(F)cc2)n(-c2ccc(S(N)(=O)=O)cc2)n1 +COc1ncc(-c2ccc3nc(NC(=O)NCCN4CCCC4)nn3c2)cc1NS(=O)(=O)c1ccc(F)cc1 +CC1(C)SC2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)O +CC(C)(O)Cc1ccc2c(c1)c1cc(OCC3CC3)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 +CCCCCCN(CCCCCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2ccc(Cl)cn12 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1ccc(C(F)(F)F)cc1 +OC1C(COC(S)=NC2CCCC2)OC(n2cnc3c(NC4CCOC4)ncnc32)C1O +Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CNc1ccc(OCC(=O)O)cc1 +COc1cc2c(-c3cc(Br)ccc3O)nc3c(c(Cc4ccccc4)nn3-c3ccccc3)c2cc1OC +COc1ccc(Nc2nc3c(-c4ccc(S(C)(=O)=O)cc4)cccn3n2)cc1 +CN1CC=C(c2c[nH]c3ccc(-c4ccsc4)cc23)CC1 +Cn1nc(-c2ccccc2)c2ccc(OCc3ccccn3)nc21 +COc1ccc(C=C(C#N)c2cc(OC)c(OC)c(OC)c2)cc1Br +COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)Cc2ccccc2)C(C)C)C(C)C)ccc1OC +Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCOC1 +O=C(CN(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2cccc(Cl)c2Cl)CC1 +O=C(O)Cc1ccc(-c2noc(-c3ccccc3)c2C(=O)CCCOc2ccc(Cl)cc2Cl)c(Cl)c1 +COC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)cc3)ccn2)c1 +Cc1cccc(-c2ocnc2C(=O)Nc2c(C)nn(CCn3ccc4ccccc43)c2C)c1 +CC(O)C(=O)N1CCC(N(Cc2cc(Cl)ccc2Cl)c2ccc(C#N)c(Cl)c2)C1 +Cn1nc(NC(=O)c2ccccc2Cl)c(Br)c1C(=O)NCCC1CCN(c2ccncc2)CC1 +COc1ccc2c(CC(C)NCC(O)c3cccc(Cl)c3)c[nH]c2c1 +O=S(=O)(c1ccccc1)n1cc(C2CCNCC2)c2ccccc21 +COc1ccccc1N1CCN(CCCCN2C(=O)C3C4C=CC(C5C=CC54)C3C2=O)CC1 +Cc1cc(O)ccc1C1=C(c2ccc(O)cc2C)C2C(S(=O)(=O)Oc3ccccc3Cl)CC1[S+]2[O-] +Cc1cc(OCC(F)(F)F)cnc1C(=O)Nc1ccc(F)c(C2(C(F)F)N=C(N)OC3CC32)c1 +Cc1csc2c(=O)n(CCCn3cncc3C)c(=S)[nH]c12 +Cc1cc(-c2cnn(C)c2)cc(C2CCN(C(=O)c3cc(C4CC4)n[nH]3)C2)n1 +CN(CC(CCN1CCC2(CC1)C[S+]([O-])c1ccccc12)c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccccc1 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(c2ccccc2-c2cnccn2)CC1 +COc1ccc(C(=O)Nc2cnc3c(c2)CN(C)CC3(C)C)cc1Br +O=C(CSc1nnccc1-c1cccc2ccccc12)Nc1ccccc1Cl +O=C(O)CC1CCC(c2ccc(NC(=O)CCNC(=O)c3nc(-c4ccc(Cl)cc4Cl)oc3C(F)(F)F)cc2)CC1 +Cc1cc(C)cc(C(CC(C)C)NC(=O)c2cc(COc3ccc(F)c(F)c3)ccc2CCC(=O)O)c1 +O=C(Nc1cc(Nc2ccc3c(c2)OCc2ccccc2C3=O)ccc1F)c1ccccc1 +O=C(NCCCCC(=O)C(F)(F)F)c1nc(-c2nc3c(s2)CCCC3)sc1C1CC1 +CN1CCN(c2ccccc2-c2ccc(C(=O)Nc3ccc(Cl)cc3C(=O)Nc3ccc(Cl)cn3)cc2)CC1 +O=c1[nH]c(C2CCC(c3ccccc3)CC2)c(Cc2cccc(C(F)(F)F)n2)c(=O)[nH]1 +Cc1cc(N2CCCC2C(=O)NCCc2ccc3c(c2)OCO3)nc(-n2ccnc2)n1 +COc1cc(C=C2CCCN(Cc3cccc(F)c3)C2=O)ccc1-n1cnc(C)c1 +O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2occc21 +COCC(NC(=O)Nc1cc2[nH]nc(-c3ccc4nnn(C)c4c3)c2cn1)c1ccccc1 +Cn1c(CN2CCC(c3ccc(C(F)(F)F)cc3)CC2)nc2ccncc21 +O=C(NN(c1ccccc1)c1ccccc1)c1ccc([N+](=O)[O-])o1 +NC(=O)c1ccc(-c2nccc3c(-c4cncnc4)cccc23)cc1NC1CCC(O)CC1 +COc1ccc(S2=NS(=O)(=O)c3cc([N+](=O)[O-])ccc32)cc1 +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3CCC(F)(F)C3)cc2n1 +Cn1nc(-c2cnc(N)c(-c3cnn(C(N)=O)c3)n2)nc1C1(c2ccccc2)CC1 +CC(C)(C)c1cc(NC(=O)C2CCN2c2ccc(C(F)(F)F)cn2)no1 +CC1CCC(=NNc2ccccc2)c2ncc(C(=O)O)c(=O)n21 +Cc1ccc(NC(=O)c2ccc(C3CCN(C)C3)cc2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CC(=O)NC1C(O)C=C(C(=O)O)OC1C(O)C(O)Cn1cc(-c2ccc(-c3ccccc3)cc2)nn1 +N=C1NC(=O)C(=Cc2ccc(O)c(C(=O)O)c2)S1 +Cc1cccc(CC(NC(=O)c2ccccc2)C(=O)NC(C#N)COCc2cccc(C(=O)O)c2)c1 +C=Cc1ccc([Si](C)(C)COc2cccc(CN(CC)CC=CC#CC(C)(C)C)c2)cc1 +CCOc1c(Cl)cccc1OC(c1ccccc1)C1CNCCO1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1nc(-c2cccc(C(C)(C)C)c2)no1 +CC(C)CC(NC(=O)c1cc(Cl)ccc1O)C(=O)NC(Cc1ccccc1)C(=O)NC(C=O)Cc1ccccc1 +NC1Cc2c(c(C(F)(F)F)nn2Cc2ccccc2)N(O)C1=O +CNCc1nc2cc(-c3c[nH]nc3C)sc2c(=O)[nH]1 +O=C1CCCC1CN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +CN(C)CCNc1nc(Nc2ccc(CCNc3nc(NCCO)nc(Nc4cccc(N)c4)n3)cc2)nc(Nc2cccc(N)c2)n1 +CC1(c2cccc(NC(=O)c3ccc(C(N)=O)cn3)c2)CCSC(N)=N1 +COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccccc2)cc1OC +CN(C)C(=O)CN1CCC(c2ccc(Nc3nc4c(-c5ccc(C#N)cc5)cccn4n3)cc2)CC1 +O=C(CCCCCC(NC(=O)C1CCC(=O)N1)C(=O)Nc1ccccc1)NO +COc1ccnc(OC)c1C1CC(C)C(=O)N1Cc1cccc(-c2nc(Cl)cs2)c1 +COc1ncc(C#N)cc1-c1ccc(C(C)NS(=O)(=O)c2c(C)noc2C)cc1 +CCOC(=O)CNc1nc(N2CCN(C)CC2)nc2ccc(Cl)cc12 +Nc1ncc(C(F)(F)F)c(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)n1 +Cc1cc(C)n2cc(C=Cc3nc(-c4ccco4)cn3C)nc2n1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCc1nn[nH]n1 +CN1CN(C2CCC(CNCC(F)F)CC2)c2c(cnc3[nH]ccc23)C1=O +O=C1N(c2ccnc(C3CC3)c2)CCN1c1cnccc1C1CC1 +COc1ccc(N2Cc3cc(C)cc(C)c3C2=O)cc1OCCN1CCC(C)CC1 +CC(C)C=C(C#N)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cccc(F)c3F)cc2)c2c(N)ncnc21 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCC(n5cccn5)CC4)ncn3)c2c1 +Clc1ccc(Cl)c(Oc2ccccc2NC(=Nc2ccccc2)NCCCNc2ccnc3cc(Cl)ccc23)c1 +c1ccc2c(c1)c1cnc(Nc3ccc(N4CCNCC4)cn3)nc1n2C1CCCC1 +O=C1CN=C(n2cnc(C3CC3)c2)C=C2c3cccc(-c4cnccc4F)c3CCN12 +Cc1cccnc1-c1cc(N2CCN(C(=O)C(C)(C)C)CC2)ncc1Cl +NCc1cccc(C=Cc2nc3ccc(F)cc3c(=O)n2-c2ccccc2Cl)n1 +Cc1c(CC(=O)O)ccc(NCc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1C +COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(F)c(Nc2ccccc2P(C)(C)=O)n1 +Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(F)c(O)c3)C(C)(C)C2=O)cn1 +Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1 +Cc1ncccc1Oc1ccc(-c2ccn(CC3CC3)c(=O)c2C#N)cc1Cl +CC1CC(C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 +CSC(=O)Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(C(=O)C(F)(F)F)C(C)C)c1=O +CNC(=O)c1cccc(C2CN(C)C(=O)c3c(O)c(C(=O)NCc4ccc(F)cc4)nn32)c1 +COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccc(C)o2)cc1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(N3CCC4(CCC4)C3)c2n1 +Cc1cc(Cl)cnc1C(=O)Nc1ccc(F)c(C2(CF)COCC(N)=N2)c1 +O=C(O)CCCC=CCC1C2CCC(C2)C1CNS(=O)(=O)c1ccccc1 +O=C(c1ccc(O)cc1)N1CCc2c(n(Cc3ccc(O)cc3)c3ccccc23)C1 +Cc1cc(C=C2C(=O)Nc3ccc(F)c(F)c32)c2ccccc(OCCCN3CCCCC3)c1-2 +O=C(CCN1CCCC1Cc1ccccc1)c1ccc2c(c1)OCCO2 +CCCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(Cc1cccc2ccccc12)NCC(O)c1cc(O)cc(O)c1 +NS(=O)(=O)OCC1OC(n2cnc3c(C#Cc4ccccc4)ncnc32)CC1O +CC1CCC(Oc2cc(C#N)ccn2)CN1C(=O)c1ccccc1CC(F)(F)F +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)s2)cn1C(C)C +OCCC1CN(Cc2ccc3nonc3c2)CCN1Cc1ccsc1 +CCS(=O)(=O)c1ccc(-c2cc(-c3cnnc4c3ncn4C(C)C)ccc2F)c(F)c1 +CCn1cc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)s2)cn1 +COc1cc(C(=O)c2sc(-c3ccccc3)nc2N)cc(OC)c1OC +COc1ccc(CC2CCCN2C(=O)c2nc(C)sc2-c2ccc3c(c2)CCO3)cc1OC +CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(NC(N)=O)sc5ccccc45)CC3)C2)N=C1C +Cc1ccc(C)c(S(=O)(=O)NC2CCC(C(=O)N3CCC4(C)c5cccc(O)c5CC3C4(C)C)C2)c1 +COC(=O)C1(C)CCCC2(C)C(CCc3ccc4c(OC(C)=O)ccc(OC(C)=O)c4c3)C3(CCC12)CO3 +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CCn2nccc2C1 +CC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1CCS(N)(=O)=O +O=c1[nH]nc(CCc2ccc(C#CC(F)F)cc2)cc1O +CP(=O)(O)CCCC=CCC1C(O)CC(O)C1C=CC(O)COc1ccccc1 +COCCN1CCN(c2ccc(Nc3ncc4ccn(C5CCCCC5)c4n3)cc2)CC1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Nc3ccc(C(=O)OC(C)C)cc3)n2)n[nH]1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(-c3ccccn3)n2)cc1OC(F)F +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1NC1CCOCC1 +O=C(NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1)C1CCOC1 +Cc1cc2nc3ccc(N(C)C)cc3[n+](-c3ccccc3)c2cc1N +CC1(c2cccc(NC(=O)c3ccc(C(F)(F)F)cn3)c2)COCC(N)=N1 +N=C(N)c1ccc(C(=O)Nc2ccc3c(c2)CC(CC(=O)O)CC3)cc1 +O=C(NCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)c1ccc(Cl)nc1 +COc1ccc(CCNC(C)C(O)COc2ccccc2)cc1OC +O=C1CSC(=S)N1CCCCNc1ccnc2cc(Cl)ccc12 +CN(C)C1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +CC1CN(c2cc(-c3n[nH]c4ccc(-c5ccc6ncnn6c5)cc34)ncn2)CC(C)O1 +COc1ccc(-n2nc(C(=O)N3CCOCC3)cc2-c2ccc(Cl)cc2)nn1 +NS(=O)(=O)c1ccc(CCNc2n[n+]([O-])c3cc4c(cc3[n+]2[O-])CCC4)cc1 +N#Cc1c(-c2ccc(OC(F)(F)F)cc2)[n+]([O-])c2ccc(C(F)(F)F)cc2[n+]1[O-] +O=S(=O)(Nc1cc(Sc2ncn[nH]2)c(O)c2ccccc12)c1ccc(C(F)(F)F)cc1 +NC(CCCCB(O)O)(C(=O)O)C1CCN(Cc2ccc(Cl)cc2)CC1 +Cc1cc(C)n(CC2OC(n3cnc4c(NC5CC6CCC5C6)ncnc43)C(O)C2O)n1 +O=C(NCCCOc1cccc(CN2CCCCC2)c1)NC1CCCCC1 +Cc1c(OCC(C)O)cn2ncnc(Oc3ccc4[nH]c(CO)cc4c3F)c12 +CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+]12CCC(CC1)CC2 +Oc1ccc(-c2ccnc3cc(Cl)ccc23)cc1CNC1CN2CCC1CC2 +CC(=O)C1=NN2c3cc(F)ccc3OCC2C1(CCCN1CCOCC1)c1ccccc1 +COc1cccc(NC(=O)NC2CCCCC2CN2CCCC(Cc3ccc(F)cc3)C2)c1 +CCNC(=O)Nc1cn2c(-c3ncc(CC)cn3)cc(-c3cccnc3)cc2n1 +COc1ccc(OC)c(-c2cccc3c(N)c4c(nc23)CN(C2CCC2)C4=O)c1 +CCC(C(O)c1ccc(O)cc1)N1CCC(O)(Cc2ccccc2)CC1 +CC[S+]([O-])c1nc(-c2ccccc2)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +COc1ccc2c(c1)CCC1(CCCCN1CCc1ccccc1)C2=O +COc1cccc2c1ncc1c(=O)n(-c3cccs3)c(=O)n(C3CCCC3)c12 +CC(Nc1nc(N)nc(N)c1Cl)c1nc2c(Cl)cc(F)cc2c(=O)n1-c1ccc(N)nc1 +Cc1c2c(cc3c(C(F)(F)F)ccnc13)C(C)CC(C)(C)N2 +O=C(CCCCCCc1ccccc1)c1noc(-c2ccccn2)n1 +COCCC(C)(F)c1nc(COc2cc(OC)cc3oc(-c4cn5nc(OC)sc5n4)cc23)cs1 +CC(C)CN(CC(C)(C)NCC(=O)N1CC(F)CC1C#N)C(=O)c1ccccc1 +O=c1nc(-c2ccc3[nH]ncc3c2)cc(-c2cccc(F)c2)[nH]1 +CCc1c(C)[nH]c2cc(OCCN(C)C)c(Cl)cc2c1=O +O=C(O)CNC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +CC1(c2cc(NC(=O)c3ncc(C(F)(F)F)cc3Cl)cc(F)c2F)CC(C(F)(F)F)OC(N)=N1 +CCNC1CCC(c2c[nH]c3ccc(N=C(N)c4cccs4)cc23)CC1 +COC1CCN(c2nc(-c3c(C)cc(C)cc3C)nc3c2CN(c2cc(C(C)C)ccc2C)CC3)CC1(C)C +O=C(NO)C1COC(c2ccc(COc3cccc([N+](=O)[O-])c3)cc2)=N1 +CCC(CC)Nc1cc(C)nc(Nc2c(C)cc(C)cc2C)c1C +Cn1ccc(Nc2nccc(-c3ccc(N4CCCC4)c(C#N)c3)n2)n1 +CCCC1CC2(CCC1O)CCN(c1ccc(OC(F)(F)F)cc1)C2=O +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2ccn(CC(C)(C)C)n2)CC1 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc31)CC2 +COc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccc(Cl)s1 +COC(=O)c1scc(-c2ccc(NC(=O)c3cccc(OC(F)(F)F)c3)cc2)c1OC +CC1(C)Oc2cc(C(=O)c3cc4ccccc4s3)cc(O)c2C2CC(O)CCC21 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+O=c1cc(-c2ccccc2F)oc2ccc3ccccc3c12 +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4ccc(Cl)cc4)cc3Cl)nc2c1 +O=C(Nc1cccc(O)c1)C(=O)c1c[nH]c2ccccc12 +Cc1c(C)c2ccc(OCC(=O)NN3C(=O)CSC3=Nc3ccc(Cl)cc3)cc2oc1=O +c1ccc(-c2cc(C3CCN(Cc4ccc(-c5nc6ncccc6cc5-c5ccccc5)cc4)CC3)n[nH]2)cc1 +CCCCc1nc2ccc(N(C)S(=O)(=O)CCC)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(C=Cc1ccc(O)c(O)c1)OCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1 +O=C(Nc1ccccc1)c1nc[nH]c1C(=O)NCCNC(=O)c1[nH]cnc1C(=O)Nc1ccccc1 +C[S+]([O-])c1cccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)c1 +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2cccc(Cl)c2)C(C(=O)NCCCN(CC)CC)C1 +CN(Cc1cccc(-c2cnc(N3CCN(c4ncccc4Cl)CC3)nc2)c1)C(=O)CN +CCN(C(=O)c1cc(C)ccc1F)c1ccnc(NC(C)c2ccccc2)n1 +O=C(O)C1CCC(CN(Cc2ccc(OCCN3C(=O)CCC3=O)c(Cl)c2)C2CCc3cc(Cl)ccc32)CC1 +Cc1ccnc(C)c1C(=O)NCCN1CCCC(CC(c2ccccc2)c2ccccc2)C1 +Cc1ccc2nc(-c3ccc(NC(=O)C4CCN(S(=O)(=O)N(C)C)CC4)cc3)sc2c1 +COc1ccc2sc(C(=O)c3cc(OC)c(OC)c(OC)c3)c(C)c2c1 +CC(C)CC(NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CSC1CCCCC1 +CN(C)CCN1C(=O)c2c(O)ccc3cc4ccccc4c(c23)C1=O +C=C(CN1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(OC)cc1 +CN(C(=O)c1ccc(F)cc1)c1nc(-c2ccncc2)cs1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OC3CCCCC3)c(C(=O)O)c2)c1 +O=C(NCc1cc(Cl)ccc1-n1cnnn1)C1CC2CC2N1C(=O)C(O)Cn1cccn1 +Cc1ncnc(N2CCC3(CCNC3=O)CC2)c1C#Cc1ccc(N)nc1 +CC(C)NC(=O)c1ccc(F)c(-c2nc(C(=O)Nc3cnccc3N3CCCC(N)C3)cs2)c1 +Cc1cc(=O)c(Oc2ccc(Br)cc2F)c(-c2ccc([S+](C)[O-])cc2)o1 +Clc1cc(NCCCN2CCCCC2)c2cc3c(nc2c1)c1cc(Cl)ccc1n3CCN1CCCC1 +CC(C)NC(=O)c1ccc(CC2CCN(C3CCN(C(=O)c4ccc(F)c5ccccc45)CC3)CC2)cc1 +O=C(Nc1ccccc1F)c1ccc(-c2cc3scnc3cc2Cl)s1 +Cc1ccc(CN2CCN(C3CCc4cccc5c4N(C3=O)C(C)(C)C5)CC2)cc1 +Cc1c(CCO)sc[n+]1CCCCc1ccc(CCCC[n+]2csc(CCO)c2C)c2ccccc12 +CS(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CN(C(=O)OC4CCOC4)C3)cc2C(N)=O)cc1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCC4(CC3)CN(C)C4)cc2c1=O +CCCCCC(C)N(Cc1ccc(CC(C)(C)C)cc1)C(Nc1ccc(OC)cc1OC)C1C(=O)OC(C)(C)OC1=O +COC1CC(C(=O)Nc2ccc(F)nc2)N(c2nc(Nc3cc(C4CC4)n[nH]3)c3cccn3n2)C1 +CC(C)NC(=O)NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 +CCOP(=O)(CC)Cc1ccc(Nc2cc(-c3ccccc3OC)ncn2)cc1 +N#CC1CCCN1C(=O)C1CCC(COc2ccc(Cl)cc2C(=O)O)N1 +O=C1NCc2nc(Sc3ccc(F)cc3)ccc2N1c1c(Cl)cc(C(F)(F)F)cc1Cl +O=C(CCCN1CCN(CCC2Cc3ccccc3C2=O)CC1)c1ccc(F)cc1 +CCCC(O)C#Cc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +COc1cc2c(cc1OC)-c1n[nH]c(-c3ccc(Br)cc3)c1C2 +CC1(C)CC(=O)c2ccc(OCc3ccccc3F)cc2O1 +Cc1cccc(C(=O)Nc2cccc(C#Cc3cncc(C(=O)N=S(=O)(CCCO)CCCO)c3)c2)c1 +COc1ccc2cnc3c(C(=O)OCc4ccco4)cnn3c2c1 +C#Cc1ccc(NCc2nc(-c3ccc4c(c3)OCO4)c(-c3cccc(C)n3)[nH]2)cc1 +Nc1ccc2c(c1)C(C#CC1CC1)(C(F)(F)F)OC(=O)N2 +O=C(O)c1cccc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)c1 +CCCCc1ncc(C=C(Cc2cccs2)C(N)=O)n1Cc1ccc(C(=O)O)cc1 +O=C(NCc1cccnc1)Nc1ccc(S(=O)(=O)N2CCC3(CCNC3)CC2)cc1 +COC(=O)C1CCCN1CCOc1ccc(Cc2ccccc2)cc1 +O=c1c(-c2ccccc2)c[nH]cc1-c1cccc(C(F)(F)F)c1 +N#CCC1(n2ccc(-c3ncnc4[nH]ccc34)c2)CN(C2CCN(C(=O)Nc3ccc(F)cc3Cl)CC2)C1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCn1cnnn1 +O=C(NC1CCCC2SCCC(C(=O)O)N2C1=O)C(S)Cc1ccccc1 +O=C(O)c1cc(-c2cccc(COc3ccc4c(c3)CN(C3CCCC3)C4=O)c2)ccc1Cl +CS(=O)(=O)CC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1c(F)cccc1F +Clc1ccc(-c2nn3ncccc3c2-c2ccnc(Nc3ccc4c(c3)OCCO4)n2)cc1 +CCCCN(CCCC)CCCOc1ccc(-c2csc(-c3cccnc3)n2)cc1 +O=C(Nc1ccc(C2=CCN(C(=O)c3ccc(Cl)cc3)CC2)cc1)N1Cc2ccccc2C1 +CNC(=O)C1OC(n2cnc3c(NCc4cccc(NC(C)=O)c4)ncnc32)C(O)C1O +CC(C)c1nc(C2CC2)cc(-c2ccc(F)cc2)c1C#CP(=O)(O)CC(O)CC(=O)O +CCNC(=O)Nc1cn(-c2ncc(C)c(CCCC(=O)O)n2)c2cc(-c3cccnc3)cnc12 +Cc1noc(C)c1-c1ccccc1CN(C(=O)c1ccc(-c2ccc(C#N)cc2)o1)c1ccc(N2CCNCC2)cc1 +CC(=O)Nc1ccc(COc2ccc(-c3ccc(-c4nc5c(C(=O)O)cc(C)cc5[nH]4)cc3)cc2)cc1 +N=C(N)c1ccc(Oc2cc(Oc3ccc(C(=N)N)cc3)cc(C(=O)NC3CCC(O)CC3)c2)cc1 +COc1ccccc1N1CCN(CCCN2C(=O)C3Nc4ccccc4C3N(C)C2=O)CC1 +COC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)c(N2CCCC2)n1C +CCN(Cc1cccs1)c1ncnc2ccc(-c3ccc4c(c3)OCO4)cc12 +CCOc1cccc(C(=O)NCCCCCC(=O)Nc2ccccc2N)c1 +NC1CCCN(c2nc3c4ccccc4[nH]c(=O)c3n2Cc2ccccc2Cl)C1 +CC(O)(COc1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(I)c1 +NCC1CCC(C(=O)NC(Cc2ccccc2)c2nc(-c3ccc(CC(N)=O)cc3)c[nH]2)CC1 +CCc1cccc(CC)c1-c1cc(C)c2c(n1)CC(C)N(c1c(Cl)c(C3CC3)nn1C)C2 +CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1ccc(F)cc1 +CN(C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)C1CCN(C(=O)N(C)C2CCN(C3CCOCC3)C2)C1 +Cc1cc(CNC(C)(C)C)ccc1C(C)Oc1cc(-c2cnc3ccccn23)sc1C(N)=O +Nc1c(S(=O)(=O)O)cc(Nc2cccc(Oc3ccccc3)c2)c2c1C(=O)c1ccccc1C2=O +Cc1cc(F)c(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC2CC2)cc1 +Cc1nc(Nc2cc(-c3cccc(NS(=O)(=O)c4ccccc4)c3)n[nH]2)cc(N2CCC(O)CC2)n1 +Nc1ncnc2c1ncn2Cc1ccc(-c2ccc(C[n+]3ccc(N4CCCC4)cc3)cc2)cc1 +Cc1cc(-c2cnn(C(C)(C)C(=O)O)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)N1CCN(c2ccccc2)CC1 +COP(=O)(OC)C(OC(=O)COc1ccc(Cl)cc1)c1ccccc1 +Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1CNCc1ccc2c(c1)CCO2 +Cn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccsc4)cc3)cc2n(C)c1=O +Cc1nccn1-c1ccc(-c2ccc3c(c2)CCC(C)N3C(=O)c2ccc(O)cc2O)nn1 +CC(O)c1nc2cc(NC(=O)c3ccc(C(C)(C)C)cc3)ccc2s1 +Cc1cc(Br)cc2[nH]c(-c3c(NC(CO)Cc4ccccc4)cc[nH]c3=O)nc12 +O=C(NC(CCN1CC2CN(C(=O)c3ccccn3)CC2C1)c1cccc(F)c1)C1CCOC1 +CC[n+]1c(C=C2Sc3ccccc3N2CCO)sc2ccccc21 +O=C(NCOCCN1CCOCC1)C1(c2ccc(Cl)c(Cl)c2)CCCCC1 +O=C(C[n+]1cc(-c2ccc(Cl)c(Cl)c2)n2c1CCC2)N1c2ccccc2Sc2ccccc21 +CC1CCCN1CCCOc1ccc(N2CCN(C(=O)c3ccc(F)cc3)CC2=O)cc1 +CCCCN1CCC(C(=O)NO)C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 +CC(=NOCCOc1ccc(CC2SC(=O)NC2=O)cc1)c1cccc(-c2ccccc2)c1 +NC1CN(c2ccncc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)CC(N)C1O +CC(C(=O)O)N1CCCCC(NC(=O)C(S)Cc2ccccc2)C1=O +CCCCC(S)C(=O)NC1(C(=O)NC(Cc2ccc(-c3ccsc3)nc2)C(=O)O)CCCC1 +CC1CN(C(C)CO)C(=O)c2cc(NC(=O)Nc3ccc(F)cc3)ccc2OC1CN(C)S(=O)(=O)c1ccc(Cl)cc1 +Nc1nc(N)c2c(n1)CCC(CNc1ccc(Cl)c(Cl)c1)C2 +OCCCCCNc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1 +CC(=O)c1ccc(NCc2cncn2Cc2ccc(-c3ccccc3)cc2)cc1-c1ccccc1 +O=S(=O)(c1ccc(-c2ccccc2)cc1)N1CCN(c2nc(Cl)ncc2Br)CC1 +O=C(NO)c1cccc(-c2csc(CSc3ccccc3)n2)c1 +Cc1ccc(CN2CCOCC2)cc1NC(=O)c1ccc(Nc2ncc(F)c(-c3ccc(OC(F)(F)F)cc3)n2)nc1 +Fc1ccccc1-c1c[nH]c2ccc(-c3nnc(NCc4ccc5[nH]ccc5c4)s3)cc12 +O=C(CCCOc1ccc(OCc2ccc3ccccc3n2)cc1)NS(=O)(=O)c1ccccc1 +Cc1ccc(-c2ncn(-c3ccc(Nc4nccc(-c5cccc(N6CCOCC6)c5)n4)cc3)n2)cn1 +COc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)CC5)ccn34)c12 +NC(N)=NCCCC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 +COc1cc2ncnc(Nc3cc(NC(=O)c4ccnc(N5CCOCC5)c4)ccc3C)c2cc1OCCN1CCCC1 +Cn1c(=O)c2c(nc(OCc3ccc(Cl)cc3)n2C)n(C)c1=O +CON(C)C(=O)C(c1ccc(-c2ccc(F)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)C1CCC(CNC)CC1 +O=C(Cc1ccccc1)Nc1nnc(CCCCc2ccc(NC(=O)C(O)c3cccc(Cl)c3)nn2)s1 +COc1cccc(CNc2nc(N)c3nc(-c4ccco4)sc3n2)c1 +COc1cccnc1Cn1ccc2nc(N)nc(OCc3ncc(C)o3)c21 +CN(C(=O)CCN1CCN(c2ccccc2)CC1)C1c2ccccc2SCC2CCCCC21 +CCCCCCCN(C(=O)Nc1ccc(C(C)C)cc1)C1Cc2ccc(SC(C)(C)C(=O)O)cc2C1 +CC(C)N1CCC(C(CN2CCN(CCCc3ccccc3-c3ccccc3)CC2)c2ccc(F)cc2)CC1 +Clc1csc2cc(Nc3nccc(-c4ccccn4)n3)ccc12 +Cn1cc(-c2ccc(-c3cncc4ccc(N5CCCC5=O)nc34)cc2)cn1 +CCCC(Oc1ccc(-n2cc(Cl)c(C)n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 +CCc1nc(C(Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)C(Cc2ccccc2)NC(=O)OC)sc1-c1ccccc1 +COc1cc(Br)ccc1NC(=O)C1CCC(N2C(=O)C3C4CCC(C4)C3C2=O)CC1 +CCCN(CCC)c1ccc2cc(C#N)c3nc4ccccc4n3c2c1 +CCCN1CCc2cc(OC)cc3c2C1Cc1ccc(O)c(O)c1-3 +Nc1cc(C(=O)NC(=O)NCCCCCC(=O)NO)ccc1Cl +COc1ccc(-c2ccc3ncc(-c4ccncc4)n3n2)cc1OC +Cc1csc2ccc(N3CCN(c4cnccc4C4CC4)C3=O)cc12 +Cc1cccc(C(=O)N2CCOCC2Cc2cc(-c3ncccn3)ccc2F)c1-n1nccn1 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(CCC(F)(F)F)C1 +CN1C2CC(S(=O)(=O)c3ccccc3)C1Cc1cnc3c(-c4ccc(Cl)c(O)c4)c(-c4ccncc4)nn3c12 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cccc3cc[nH]c23)cc1 +COc1csc(-c2ccc(OCCCOc3ccc4c(c3)CCC4CC(=O)O)c(OC)c2)n1 +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(CN5CCC(O)CC5)cc4)c3)c(OC)cc21 +Cn1nnnc1-c1cccc(CC2(C(=O)NC(Cc3ccc(NC(=O)c4c(Cl)cccc4Cl)cc3)C(=O)O)CCCC2)c1 +CCCCN1CCCC(c2ccc(C(=O)N(CC)CC)cc2)(c2cccc(O)c2)C1 +C#CCN1CCN(C(=O)c2c(F)cc(-c3ncnc(CC)c3C#Cc3ccc(N)nc3)cc2F)CC1 +COC(=O)c1ccc2c(Nc3ccc(Cl)cc3)nc(N3CCOCC3)nc2c1 +Cc1cc(-c2nnc(N)nc2-c2cccc(F)c2)cc(C)n1 +COC(=O)C1C2CCC(CC1c1ccc(-c3nccs3)cc1)N2 +O=C(Cn1cc(Nc2nncc3cc(OCCCN4CCCC4CO)ccc23)cn1)Nc1cccc(F)c1 +O=C(NCc1ccc(Oc2ccccc2)cc1)C(CSCC1CCCCC1)NC(=O)C1CSCN1CCO +N#Cc1cc(-c2ccc(F)cc2)ccc1N1CCOc2cc(S(=O)(=O)Nc3nccs3)ccc21 +O=C(O)CC1CC2(CCN(C(=O)NC3C4CC5CC(C4)CC3C5)CC2)c2cc(Cl)ccc21 +CCCN(CCOc1cccc(CN(CC)CC=CC#CC(C)(C)C)c1)S(=O)(=O)c1cccs1 +Nc1nc(-c2cccc(C(=O)N3CCOCC3)c2)cn2nc(-c3ccco3)nc12 +O=C1Nc2c(ccc(F)c2F)C1(CC1CCCCC1)c1ccc(O)cc1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2c(c1)OCO2 +Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2ccc(C(N)=O)cn12 +CN(C)c1cccc2c(S(=O)(=O)NCCNC(=O)NC34CC5CC(CC(C5)C3)C4)cccc12 +O=c1[nH]ccc2cc(OCCCN3CCN(c4cccc5sccc45)CC3)ccc12 +CC(Oc1cc2onc(CCC(=O)O)c2cc1Cl)c1ccc(Cl)cn1 +Cc1c(Cl)cccc1C(=O)N1CCCC(c2nc(-c3ccccc3Br)no2)C1 +Cc1ccccc1C(C(=O)NC1CCOCC1)N(C(=O)Cc1cccs1)c1cccc(F)c1 +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCc2ccc(CNC(=O)c3ccc(C(F)(F)F)cc3)cc2)C1 +COc1cc(C=C2CC(C(C)C)CC(=Cc3cc(OC)c(OC)c(OC)c3Br)C2=O)c(Br)c(OC)c1OC +Cc1cc(-c2cc(C(=O)c3cccc(O)c3)cs2)ccc1O +Cc1c[nH]c2ncnc(N3CC(C)N(C(=O)Nc4cccc(Br)c4)C(C)C3)c12 +O=C(CCCCNC1=NCCCN1)Nc1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2)C(=O)O)cc1 +COc1cc(C=C2CCCN3C2=NOCC3C(C)(C)C)ccc1-n1cnc(C)c1 +Cn1ncc(C(=O)N2CCC(Nc3cc(=O)n(C)c4cc(F)c(F)cc34)CC2)c1Cl +COc1cc2c(cc1N1CC(C)N(C)C(C)C1)N(C(=O)Oc1cccc(C(F)(F)F)c1Cl)CC2 +COc1ccc([N+](=O)[O-])cc1Nc1nc2c(s1)CCCCc1nc(NC(=O)C(C)(C)C)sc1-2 +CC(=O)Nc1nc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(C#N)cc2)n1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCN(C)C +CCCC1SC(=Cc2nc3cccc(C)c3[nH]2)NC1=O +Cc1[nH]c2ccccc2c1CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +O=C(O)COc1ccc(SCc2ccc(OCc3ccc(F)cc3)cc2)c2c1CCC2 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3ccccc3C(F)(F)F)cc2)C1CO +Cn1cc(-c2cccc(F)c2F)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O +COc1ccc2cnn(-c3cnc4[nH]cc(C(=O)NC(C)(C)C)c4n3)c2c1 +O=C(CCCCCCNC(=O)c1nc(-c2nccs2)sc1C1CC1)NO +COc1ccc(-c2cc(=O)[nH]c(=S)n2CCO)c(OC)c1 +CCc1n[n+]([O-])c2cc(OCCN(C)C)ccc2[n+]1[O-] +Cn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)NC3 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2cnc(CC3CCCC3)o2)cc1 +COc1cc(C(=O)c2ccn(-c3cccc(O)c3)c2)cc(OC)c1OC +CCCN(CC1CC1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 +Cc1cc(C#N)cc(C)c1Oc1ccc([N+](=O)[O-])c(NC2CCN(Cc3ccccc3)CC2)c1 +O=C(NCCc1nc(-c2ccc(F)cc2)cs1)c1cccs1 +Cn1cc(-c2cnn3c(Nc4ccccc4)cc(C4CCCNC4)nc23)cn1 +O=C(O)CC(=O)Nc1cccnc1C(=O)Nc1nccs1 +CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c2nncn12 +CCCCn1nc(-c2nc3ccccc3s2)nc2c(=O)n(CC)c(=O)nc1-2 +O=C(CCCCCn1cc(-c2ccc3cccnc3c2)nn1)NO +O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(F)cccc2Cl)c2ccc(=O)[nH]c2c1=O +CCOCCOc1cc2c(ccn2C(=O)NC)cc1Oc1ccnc(NC(=O)c2ccc(C3CCN(CCO)CC3)cc2)c1 +COC(=O)Cc1sc2nc(-c3cccs3)nc(NN3C(=O)C=C(C)C3=O)c2c1C +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4cccc(OCCCO)c4)c3)ncnc12 +Oc1nc(-c2cc(-c3ccon3)n(Cc3ccc(F)cc3F)n2)ncc1F +COCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3cc(Cl)ccc3Br)cc2[nH]1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccc(O)cc1Cl +Cc1c(C(=O)NCCCN2CCN(c3cccc(Cl)c3)CC2)cc(-c2ccccc2)n1C +OCc1ccc(-c2cn3c(-c4cn[nH]c4)cnc3cn2)cc1 +COc1cccc(CCNc2nc(N)c(C(=O)N=C(N)N)nc2Cl)c1 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1ccccc1CCN +Nc1ccccc1NC(=O)C=Cc1cccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)c1 +CC(C)N(C(=O)C1CCC2C3CCc4cc(CP(=O)(O)O)ccc4C3CCC12C)C(C)C +COc1cccc(OC)c1-c1cc(C(=O)NC2(C(=O)O)CCCCC2)nn1-c1ccnc2cc(Cl)ccc12 +O=C(c1cn(C(=O)OCc2ccccc2)c2ccccc12)C1CSC(c2cccnc2)N1 +CC(C)CN(c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1)S(=O)(=O)N(C)Cc1ccc(F)cc1 +CC1COCCN1c1ccnc(-c2c[nH]c3ccc(-c4nnc(N)o4)cc23)n1 +COC=CC12CCC(O)CC1=CCC1C2CCC2(C)C(O)CCC12 +COc1ccc(Nc2ncc(CN3CC4(C3)NC(=O)NC4=O)cc2-c2nc(C)nc(N)n2)cn1 +Cc1nc(O)c2cc(NCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)s3)ccc2n1 +COC(=O)C(Cc1cccs1)NC(=O)c1c(C)n(CCN2CCOCC2)c2c(OC)cccc12 +CC(C(O)c1ccc2c(c1)CN(C)C(=O)N2)N1CCC(O)(c2ccc(F)cc2)CC1 +CN(C)CCNc1cc(-c2ccc(N3CCN(C)CC3)cc2)nc2ccccc12 +Cc1ccc(C(=O)N2CCC3(CC2)OCc2cc(C#N)ccc23)cc1NC(=O)c1ccc(N(C)CCO)nc1 +CSCCC(NC(=O)c1ccc(CSc2cccnc2)cc1-c1ccccc1)C(=O)O +O=C(Cn1c(-c2ccc(F)cc2)nc2ccccc21)Nc1ccc(Cl)cc1 +CCn1cnc2c(Nc3cccc(OC)c3)nc(NCCN)nc21 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+CC(C)(O)C1CC(Nc2nc(-c3cc(F)ccc3O)nc3ccccc23)CN1 +COc1cc(NC(C)CCCN(Cc2ccccc2OC)C(=O)Nc2cccc(F)c2)c2ncccc2c1 +CN(C)C1(c2ccccc2)CCC(c2ccccc2)(N(C)C(=O)NCc2ccccc2)CC1 +COc1ccc2c(c1)C(CCNC(=O)C(F)(F)F)=CC2 +N=C(N)NC1CCC(C(=O)Nc2ccc(CC(NC(=O)C3CCCN3S(=O)(=O)c3ccccc3)C(=O)O)cc2)CC1 +O=C1OC(=CCn2c(=O)[nH]c(=O)[nH]c2=O)C(OCc2ccccc2)=C1OCc1ccccc1 +Nc1nnc(-c2ccc3[nH]cc(-c4nccc(Nc5ccccc5)n4)c3c2)o1 +CC1(c2cc(NC(=O)c3cnc(C(F)F)cn3)cc(F)c2F)CC(C(F)(F)F)OC(N)=N1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN2CCC(C)(C)C2=O)c1C +CN(C)CCOc1ccc(-c2cccc(N)n2)c2ccccc12 +CCSc1ccn(C2OC(COP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)n1 +CCOC(=O)c1nnc(-c2ccccc2)nc1Sc1ccccc1Cl +COP(=O)(O)CNC(Cc1ccc(-c2ccccc2)cc1)C(=O)NCCC(=O)O +CCCCCCCCNC(=O)c1cn2c3c(c(N4CCN(C)CC4)c(F)cc3c1=O)OCC2C +Oc1ccc(-c2ccc(-c3cn(CSc4ccccc4)nn3)cc2)cc1 +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4cc(OC)c(O)cc4[nH]3)CC3CC123 +Cc1cc(OCCCc2c(C(=O)O)sc3ccccc23)cc(C)c1Cl +COc1ccc(S(=O)(=O)N2CCCNCC2C(=O)NO)cc1 +c1ccc(-c2cc(-c3ccncc3)c(-c3cccs3)[nH]2)cc1 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+COc1ccc(C2CC2COc2nc(C)ncc2-c2cc(=O)n(C)cc2C#N)nc1 +O=C(O)CC(NC(=O)CNC(=O)c1cc(O)cc(NC2=NCCCN2)c1)c1cc(Br)cc(Br)c1O +Cc1ccc2nc(C)c3nnc(-c4cc(C(C)O)ccc4Cl)n3c2n1 +COC(=O)c1ccc(Cn2c(=O)n(Cc3nc4ccccc4n3CCN(C)C)c3ccccc32)cc1 +c1cc(-c2ncco2)c2c(c1)C(c1ncc[nH]1)CC2 +O=C(NCc1ccc(OC(F)(F)F)cc1)Nc1cccc2ccc(O)cc12 +CCCCCc1ccc(C(=O)N(CCN2CCC(Cc3ccccc3)CC2)Cc2ccc(-c3ccc4c(c3)OCO4)cc2)cc1 +CCNC(=O)Nc1cn(-c2nccc(C)n2)c2cc(-c3cccnc3)cnc12 +CCOC(=O)C1Oc2ccc(CNC(=O)C3SCCN3C(=O)CC(N)Cc3cc(F)c(F)cc3F)cc2O1 +NC(=O)c1cc(-c2ccccc2)cc2c1[nH]c1ccc(C(=O)N3CCOCC3)cc12 +CCOc1ccc(-n2c(C)c3c(C)nnc(CC(C)C)c3c2C)cc1 +CNc1cccc(F)c1C(=O)OC1C(C)=CC23C(=O)C(C=C(CO)C(O)C12O)C1C(CC3C)C1(C)C +CC1(O)CCC(Nc2ccc3nnc(-c4cccc(C(F)(F)F)c4)n3c2)CC1 +N#Cc1c2c(c(N3CCN(Cc4ccccc4)CC3)n3c1nc1ccccc13)CCC2 +CC(C)C(NS(=O)(=O)c1ccc(-c2cccc(F)c2)cc1)P(=O)(O)O +O=C(Nc1nc2ccccc2n1CCN1CCCC1)c1ccc(Cl)cc1 +COCc1cc(C#N)cnc1C(=O)Nc1ccc(F)c(C2(C(F)F)N=C(N)OC3CC32)c1 +CN1CCN(C)C(C)(c2nc(O)c(O)c(C(=O)NCc3ccc(F)cc3)n2)C1 +C=CCOC(=O)C1=CSC2C(C(C)OC(C)=O)C(=O)N12 +C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(OCC(=O)O)c1 +CC(C)NC(=O)c1ccc2cc(C(O)(c3c[nH]cn3)C(C)C)ccc2c1 +CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(C)ccnc3C)CC2)CC1 +Cc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +O=C(NO)c1cnc(NC2(c3ccc(F)c(F)c3)CC2)nc1 +CC(NC1CCN(c2ccc(C(=O)NC(CO)(CO)CO)cc2)C1)c1cccc2ccccc12 +Cc1cnc2c(NCCN(C)C)nc3cc(-c4ccccc4)sc3n12 +CC1(C(=O)Nc2nccs2)CC2c3ccccc3C1c1ccccc12 +NC1=NC2(CO1)c1cc(Br)ccc1OC(Cc1ccccc1)C21COC1 +O=C(NCCC1(N2CCOCC2)CCCC1)c1cc2[nH]c(=O)c3ccccc3n2n1 +COC1C(O)C(O)C(Oc2ccc3cc(NC(=O)c4cc5ccccc5[nH]4)c(=O)oc3c2C)OC1(C)C +CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(C#N)ccc2OCC(=O)O)c1 +C=CCC(C(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)C(C)C)c1cc(Br)ccc1OC +COCCCn1c(NC(=O)c2ccc(Cl)cc2)nc2cc(CN(C)C3CCCCC3)ccc21 +CN(C(=O)Cc1cccc2occc12)C1CCC2(CCCO2)CC1N1CCCC1 +FC(F)(F)c1cccc(Sc2ccc3nnc(-c4ccncc4)n3n2)c1 +CCOc1ccc(F)c(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)c1 +Cc1ccc(Nc2cnc(-c3cccc(OC(C)C)c3)c(C)c2)c(C(=O)O)c1 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+CCC(=O)N1N=C(c2ccccc2)CC1c1ccc(Cl)cc1 +CCOC(=O)Cn1c2ccc(OC)cc2c2nc3ccccc3nc21 +O=C(NC1Cc2ccccc2C1)c1cccc(-c2n[nH]c3ccc(-c4ncn[nH]4)cc23)c1 +CCCOC(=O)Nc1ccc2oc3cc(S(=O)(=O)NC(C(=O)O)C(C)C)ccc3c2c1 +CCc1cccc(OC)c1CCc1ccc(O)c(C(=O)OC)c1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)CNC(C)C(=O)NCC(C)C)c1 +COC(=O)CCC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1 +O=C(Cc1cc[n+]([O-])cc1)N1CCN(C2c3ncc(Br)cc3CCc3cc(Cl)cc(F)c32)CC1 +CCC1C(C)C(Nc2ccccc2)c2ccccc2N1C(=O)c1ccc(OC)cc1 +Cc1[nH]c(C)c(-c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)c(=O)c1Br +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC(CNS(=O)(=O)N1CCOCC1)c1ccccc1 +CN1CCC(OCC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)CC1 +COc1ccc(-n2c(=O)[nH]c3cc(C(=O)NCc4ccc5c(c4)OCO5)sc3c2=O)nc1OC +Cc1c2c(n3c1CCCNCC(C)(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +COc1ccc(C(=O)C(Cc2cc(OC)c(OC)c(OC)c2)=C(C(=O)O)c2ccc3nsnc3c2)cc1Cl +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccncc4)nc23)N1 +COCCN(CCOC)CCC(C)(C)Nc1nc2c(-c3cc4c([nH]3)CNC4=O)cccc2c(=O)n1C 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+CN1CCN(c2nc(-c3ccco3)cc(-c3cccs3)n2)CC1 +COC(=O)C(N)CCB1OC2(C)CCC3CC2(O1)C3(C)C +CC(C)S(=O)(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1 +CN1C(=N)NC(C)(c2sc(-c3cc(F)cc(-c4cnco4)c3)cc2F)CS1(=O)=O +CC(NC(=O)N1CCC(c2ccc(O)cc2O)CC1)c1ccccc1 +CC(=O)N1CCN(C(=O)c2cccc(Sc3cnc(NC(=O)c4ccc(N(C)C)cc4)s3)c2)CC1 +Cc1c(-c2nnc(C3(c4ccc(Cl)cc4)CC3)o2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +CCNC(=S)Nc1cc(-n2cnc(CN(C)C)c2)ncn1 +CC(C)(C)n1c(=O)[nH]c2cc(Nc3ccccc3)ccc21 +Nc1cccc(N2CCN(CCCN3C(=O)CCc4c(Cl)cccc43)CC2)c1 +Cc1ncoc1-c1nnc(SCCCN2CCC3(CC3c3ccc(F)cc3)C2)n1C +Cc1c(S(=O)(=O)C(F)(F)F)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 +CS(=O)(=O)c1ccc(C(=Cc2ccccc2)c2ccccc2)cc1 +CCCCCCc1csc(-c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)n1 +CNC(=O)Nc1ccc(-c2cc(-c3ccnc(Nc4ccc(C)c(S(=O)(=O)N(C)C)c4)n3)ccn2)cc1 +c1ccc(CCn2c(N3CCNCC3)nc3ccccc32)cc1 +CC1CN(c2ncc(C(=O)NCc3ccc(Cl)c(Cl)c3)cc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +CC(Br)C=CC(=O)N(Cc1ccc(Cl)cc1)CC(C)C +COc1cc(C(C)(C)C(=O)NCc2ccc(C(C)(C)C)cc2)ccc1NS(C)(=O)=O +CCS(=O)(=O)Nc1cc(Cl)cc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +CCn1ncc2c(F)cc(C(=O)Nc3nnc(C4(C)CN(C(C)=O)C4)s3)cc21 +O=C(CCc1cnnn1-c1ccccc1)c1cccc(F)c1 +O=C1Nc2cccnc2N(C(=O)CN2CCCCC2CN2CCCCC2)c2ccccc21 +O=C(Cc1cccc2ccccc12)N1CCC(CNCCCCNCC2CCCCC2)CC1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1-n1cc(-c2cncc(N(C)C3CCOC3)c2)nn1 +COc1ccc2c3c(c(=O)oc2c1)CN(Cc1ccc(C)cc1)CC3 +Cc1noc(-c2ccc(Nc3nn(C4(CC#N)CCN(C(=O)OC(C)(C)C)CC4)cc3C(N)=O)cc2)n1 +O=C(Nc1ccc2c(c1)OC(F)(F)O2)c1ccccc1NCc1ccnc(NCCCn2ccnc2)c1 +COc1cc(-n2cnc3cc(-c4cccc(I)c4)sc3c2=O)ccc1OCCN1CCCC1 +CS(=O)(=O)NC(CNC(=O)c1cc2sc(CCC3CCNCC3)cc2s1)C(=O)O +CC12CCC(C1)C(C)(C)C2NC(=O)c1cn(CCCCO)c2cc(F)ccc2c1=O +CC=C1C(O)CC2C3CCC4CC(N5CCCCC5)CCC4(C)C3CCC12C +COC1Cc2sccc2C2(CCN(CCc3ccccc3)CC2)O1 +CS(=O)(=O)c1ccc(-c2c(-c3ccc(F)cc3)nc3sccn23)cc1 +CC1(C)C=C(CSc2nc3c(C(N)=O)cccc3[nH]2)CC(C)(C)N1O +CS(=O)(=O)c1ccc(-n2nc(C(F)F)c(C#N)c2-c2cc(F)cc(F)c2)cc1 +COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)Cc5ccccc5)cc43)c2=O)CC1 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+O=C1CC(NC(=O)C2COCC3CC=CCC(NC(=O)c4ccc5ccccc5c4)C(=O)N32)C(O)O1 +COc1nc2ccc(C(O)(c3ccccc3)C3CCN(C(C)=O)CC3)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 +CC(=O)OC1(C)CCC2CC1OOC2(C)C[S+]([O-])c1ccccc1 +CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(=O)O)c1C +N#Cc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCO)CC1 +Cc1cc(SC2=C(O)OC(CCC3CCCO3)(C(C)C)CC2=O)c(C(C)(C)C)cc1CO +COc1cc(F)cc(C#Cc2c(N)ncnc2NC(C)c2nc3cccc(Cl)c3c(=O)n2-c2ccccc2)c1 +CCCC[N+]12CCC(CC1)C(NC(=O)c1cc(Cl)c(N)c3c1OCC3)C2 +CC#Cc1ccc2nccc(NC(=O)Nc3cccc(C(F)(F)F)n3)c2c1 +CCOc1cc(=O)n(C)cc1-c1cc(N(Cc2cncnc2)S(=O)(=O)CC)ccc1Oc1ccc(F)cc1F +FC(F)Oc1ccc(Cl)cc1CN1CCN(c2nc3cnccc3nc2NC2CC2)CC1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2cccc(OC(F)(F)F)c2)[nH]c1=O +CCOC(=O)Cn1c2ccc([N+](=O)[O-])cc2c2ncnc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c21 +C=CCn1c(SCC(=O)Nc2cc3oc4ccccc4c3cc2OC)nnc1-c1cnccn1 +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)N1CCCN(C(=O)c2ccccc2O)CC1 +Nc1ccc2ccc(CCNCCCc3cccc(F)c3)cc2n1 +CCN(CC)CCCCNc1cc2nc(NC(=O)NC(C)(C)C)c(-c3cc(OC)cc(OC)c3)cc2cn1 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+COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C(N)=NC#N)CC1 +CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCCCN1CCOCC1 +COc1sc(S(=O)(=O)NC(=O)Nc2ncc(Br)s2)cc1C +CCCCNC(=O)NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(-c3cccc(CO)c3)nc21 +CCCCCC=CCC=CCC=CCC=CCCCC1=NC(C)CO1 +CC12C3CCC(C3)C1CN(c1ccc(C#N)c(C(F)(F)F)c1)S2(=O)=O +O=C1Cc2cccc(Oc3ccc(Nc4ncnc5ccn(CCO)c45)cc3Cl)c2N1 +CC(C)(C)C(=O)OCOP(=O)(COC(CO)Cn1cnc(N)nc1=O)OCOC(=O)C(C)(C)C +COc1ccncc1C(=O)Nc1cn2nc(-c3cn(C)nc3-c3ccc(F)cc3)ccc2n1 +CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(Cl)c5)CC4)cc3)[nH]c2c1=O +COc1ccccc1C(N)CNc1cc(C)nc2nc(NC(CC#N)c3cccc(Cl)c3)nn12 +CC(=O)c1cnc2cc(F)c(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(CN(C)C)CC1 +COc1ccc(S(=O)(=O)N2CCc3cccc(NC(=O)C(C)(C)C)c32)cc1 +CN(C)C1(CNCCc2ccccc2)COc2ccccc2OC1 +CC(C)S(=O)(=O)CC(N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1)C(C)(C)C +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1N1CC2CC2C1 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+O=C(NCC1CCCN1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 +Nc1nc(N)c(CCCN(C=O)c2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)c(O)n1 +NC(=O)c1ccc2[nH]c(-c3ccc(OC4CCCN(Cc5ccc(Cl)cc5)C4)cc3)nc2c1 +O=C(NCc1ccc(OC(F)(F)F)cc1)c1ncc([N+](=O)[O-])[nH]1 +CCOCCn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 +O=C1c2ccc(Cl)cc2CCC12CCN(CCc1ccccc1)CC2 +O=C(Nc1cccnc1)c1cc(Cl)ccc1OCc1ccccc1 +COc1cccc2c1-c1ccc(NS(C)(=O)=O)cc1C(c1cccc(C)c1)O2 +Cc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccc(OCCCN(C)C)cc3Cl)nc1-2 +CCOc1ccccc1-c1cc(F)c(NC(=O)c2cscc2C(=O)O)c(F)c1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2cccnc2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(Nc3ccccc3)c2cn1)c1ccccc1 +COc1ccc2c(Oc3ccc(NC(=O)c4c(-c5cc(C)on5)n(C)n(-c5ccccc5)c4=O)nc3)ccnc2c1 +CCCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2C)cc1 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1cccc2nonc12 +Cc1nsc(C2CCN(C(=O)C3CNC(C(=O)N4CCCC4)C3)CC2)n1 +O=C(O)c1ccc2c(c1)nc(-c1ccc(OC(c3ccc(F)cc3)c3ccc(F)cc3)cc1)n2C1CCCCC1 +CCOc1cc(C=C2CN(C)CC(=Cc3ccc(O)c(OCC)c3)C2=O)ccc1O +Cc1ccc(C(=O)OC2(c3ccc(Cl)cc3)CCN(CCCC(=O)c3ccc(F)cc3)CC2)cc1 +O=C(NCCCCN1CCN(c2ccc(F)cc2)CC1)c1cc2ccccc2cn1 +COc1ccc(-c2cccc3cnc(Nc4ccc(-n5cnc(-c6ccccn6)n5)cc4)nc23)cc1F +N=C(N)c1ccc(OCCCCCCOc2ccc(C(=N)N)cc2)cc1 +O=S(=O)(NC1CCC(N2CCC(c3ccccc3OC3CC3)CC2)CC1)c1ccc2c(c1)OCO2 +COc1cc2[nH]c(=O)n(CCc3c[nH]cn3)c(=O)c2cc1-c1cnco1 +CC(C)CN(c1ccc(F)cc1)S(=O)(=O)c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1 +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5nc(C)sc5c4)c3c2)C1 +Nc1nc(N)c(-c2cccc(Cl)c2)c(CCCc2ccccc2)n1 +OCC1OC(n2cnc3c(CSc4ccc(I)cc4)ncnc32)C(O)C1O +CC(C)COc1cc(-c2ccc(CC(C)NCC(O)c3ccccc3)cc2)ccc1C(=O)O +COC(=O)c1ccccc1S(=O)(=O)CCn1c([N+](=O)[O-])cnc1C +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3ccco3)c3ccccc32)CC1 +O=C(Cc1ccc(Cl)c(Cl)c1)N1CCc2occc2C1CN1CCCC1 +Cc1ccccc1-n1c(Cn2nc(-c3cc(O)cc(F)c3)c3c(N)ncnc32)nc2cccc(C)c2c1=O +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CCC1C(=O)NN(C)C +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccco2)[nH]c1=O +CCCC(=O)N(Cc1ccc2c(c1)OCCO2)c1cc(-c2nnn[nH]2)ccc1F +O=C1COc2cc(Cl)c(Cl)cc2N1CC(=O)N1CCCC(c2ccccc2)C1CN1CCOCC1 +CCCCN(CC)c1cc(C)nc2c1NC(=O)CN2c1ccc(Cl)cc1Cl +CCN(CC)c1ccc(N=Cc2ccc(Sc3nc4ccccc4s3)o2)cc1 +C=C1CC(COC2CCC3(OC(C)=O)C4Cc5ccc(O)c6c5C3(CCN4CC3CC3)C2O6)OC1=O +CN(CC(=O)O)Cc1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)cc1 +CC(NC(=O)CCc1nc2cccnc2n1Cc1ccccc1)c1ccccc1 +N#Cc1ccc(Cn2cncc2CNC2C(=O)N(c3cc(Cl)cc(Cl)c3)CCc3ccccc32)cc1 +CC(C)Oc1ccc(C(C)Nc2ncc(F)c(N3C(=O)OCC3C(C)C)n2)cc1 +NCCCCCNc1cc(-c2ccc(F)cc2)nc2ccccc12 +Nc1nc(Cl)c(-c2nc3ccccc3s2)c(NC2CC(CO)C(O)C2O)n1 +Cc1cn(CCCCN2CCN(c3cc(C(F)(F)F)nc(C(C)(C)C)n3)CC2)c(=O)[nH]c1=O +OCc1csc(-c2ccnc(Nc3cc(O)cc(C(F)(F)F)c3)n2)n1 +FC(F)(F)c1cccc(-c2nnc3ccc(NC4CCOCC4)nn23)c1 +COc1ccccc1-c1ccc2c(ccc3sc4c(c32)NCC(C)NC4=O)n1 +Cc1ccn2nc(CCc3nc(N4CCCC4)n(C)n3)nc2c1C +O=c1c(Nc2ccccc2)c(Nc2ccc(Cl)c(S(=O)(=O)N3CCC(N4CCCCC4)CC3)c2O)c1=O +CCOC(=O)c1cc(CCn2cnc3c2NC=NCC3O)c2c(c1OCc1ccccc1)CCCC2 +CC(C)C1CCC(N2CCC3(CC2)C(c2ccccc2)CC2CN(C)CC23)CC1 +CCN(Cc1ccncc1)C(=O)Cc1c(-c2ccccc2)[nH]c2ccccc12 +FC(F)(F)c1ccc(C(NC2CN(c3ncccn3)C2)c2cccnc2)cc1 +CCOC1(c2ccccc2)c2cc(Cl)ccc2NC(=O)N1C +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(N(C)CCCO)cc3)CC21C +Cc1cccc(C(=O)N2CCN(CC(N)CS)CC2)c1C +NC1(C(=O)O)C(OCc2ccc(-c3ccccc3)cc2)CC2C1C2(F)C(=O)O +COc1ccc(-c2cn(-c3ccccc3)c3ncnc(N)c23)cc1 +N#CCOc1c(-c2ccccc2)c(O)nc2cc(Cl)ccc12 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc(N2CCOCC2)c2sccc2n1 +O=C(NCc1ccc(-c2cc(NC(=O)c3ccc(OCCN4CCCC4)cc3)[nH]n2)cc1)OCc1cccnc1 +CN(C)CC(=O)N1CCC(c2nc(-c3cnc(N)c(-n4nnc5ccccc54)n3)nn2C)CC1 +CC(=O)Nc1cccc(C2CCN(CCCn3nc(-c4ccc(Cl)cc4)c4cc(F)ccc4c3=O)CC2)c1 +Cc1cc(C(=O)NCCc2ccc(-c3ccccc3)cc2)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)O +CN(C)c1ccc(Oc2ccc3c(Cn4ccnc4)cc(=O)oc3c2)cc1 +O=C(O)COc1ccc(Cl)cc1CN1CCCN(S(=O)(=O)Cc2ccccc2)CC1 +CC(=O)c1nn(CC(=O)N2C(C(=O)NCC3C(C)(C)C3(Cl)Cl)CC3CC32)c2ccc(OCc3ncccn3)cc12 +CC(CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)sc12 +CCCCCN(C)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(Cl)cc12 +c1ccc2c3c([nH]c2c1)C(Cc1ccc2c(c1)OCO2)NCC3 +O=C(c1cccs1)N(c1ccccc1)C1CCN(Cc2ccccc2)CC1 +COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccccc2)CC1 +CS(=O)(=O)c1ccc2c(c1)CCN2C(=O)COc1ccc(Cl)c(Oc2cc(Cl)cc(C#N)c2)c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc31)CC2 +COc1cccc2sc(Nc3nc(-c4ccccn4)cs3)nc12 +Cc1ccc(-n2nc(Nc3cc(C)[nH]n3)c3ccccc3c2=O)cc1 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(OCCCN(C)C)cc2)nc1 +CS(=O)(=O)NCCc1cn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 +O=C(NCCCCCCNC(=O)N1Cc2ccncc2C1)c1ccccc1 +O=C(NC1CC(C(=O)O)Nc2cc(Cl)cc(Cl)c21)OCc1ccccc1 +O=C(O)c1cc2[nH]c(-c3ccccc3)c(C3CCCCC3)c2s1 +Cn1nc(C(=O)N2CCc3ccccc3C2)c2c1CCC(N1CCN(Cc3cccc(F)c3)CC1)C2 +CN(Cc1nc(CC2(C3CCCC(C4CC4)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)no1)C(C)(C)CO +CC(O)(c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1)C(F)(F)F +COc1cc(C(=O)c2c(N)sc(C#Cc3ccsc3)c2C)cc(OC)c1OC +C[Se]c1ccc(N(C)c2nc(C)nc3ccccc23)cc1C +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(O)c(C(=O)O)c1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(C(=O)OC(C)(C)C)cc1 +COCCN1CCN(c2cc(-c3n[nH]c4ccc(OC(C)C)cc34)ncn2)CC1 +O=C(NCc1cn(Cc2ccccc2)nn1)c1cn(Cc2ccccc2)nn1 +O=S(=O)(Nc1ccc(CCCC2CCCC2)cc1F)c1ccc2c(c1)CCN(Cc1cnn(C3CCC3)c1)C2 +CCOc1ccc(-c2cc3c(ncn3CCCN3CCOCC3)c(C#N)n2)cc1C(F)(F)F +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C(CO)N(C)C +Cn1c(COC(c2ccc(C#N)cc2)c2c[nH]cn2)c(-c2cccc(Cl)c2)cc(C#N)c1=O +COc1nc(Cl)ccc1-c1nccc2cc(S(=O)(=O)Nc3nccs3)ccc12 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)ccc21 +O=C(NCc1ccccc1)c1cnc2nc(NCCc3ccccc3)ccc2c1O +CC1(C)C=C(c2nc3ccccc3[nH]2)CC(C)(C)N1 +Cc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2[nH]c(CCc3ccccc3)nc12 +COc1cccc(C#N)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CC(CO)Nc1ncc2c(n1)CN(C(=O)NC(C)c1ccc(Cl)c(Cl)c1)CC2 +COc1ccc([N+](=O)[O-])cc1CSc1nc2cc(NC(=O)NC(C)(C)C)ccc2n1C1CC1 +CC(C)CC1CC(O)=C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)C(=O)N1Cc1ccc(F)cc1 +CCCCN(C)C(=O)Cc1c(-c2ccccc2)nc2c(Cl)cc(Cl)cn12 +COc1cccc(NC(=O)c2ccc(Nc3ccccc3)c([N+](=O)[O-])c2)c1 +COc1cccc(-c2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)c1 +CNC(=O)c1ccccc1CCC1(O)CCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C +CCc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2[nH]ncc2c1 +CC1CN(C(=O)C(C)(O)C(F)(F)F)CCN1C(=O)c1ccc(C(=O)c2ccccc2)cc1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCCN(C(C)C)CC3)[nH]c12 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1cccc(O)c1)O2)C(C)=CC(C)(C)N3 +CCN(CC)Cc1ccc(COc2ccc(C(C)=O)cc2)cc1 +CC(=O)c1ccc(NC(=O)CN2CCC(N3C(=O)OCc4ccccc43)CC2)cc1 +O=C(Nc1cccc2cccnc12)c1ccc(N2CC3C4C=CC(C4)C3C2)cc1 +COc1cc2nc(N(C)CCCCCCN(C)C(=O)C3COc4ccccc4O3)nc(N)c2cc1OC +CCC1CN(c2ncc(-c3ncc[nH]3)nc2C)C(C)CN1C1CCN(C(=O)c2ccc(Cl)nc2N)CC1 +O=[N+]([O-])c1ccccc1Nc1nnc(-c2c[nH]c3ccccc23)o1 +NCCCCN(CC1Cc2ccccc2CN1Cc1cccnc1)C1CCCc2cccnc21 +CN1CCc2ccccc2Cc2[nH]c3ccc(O)cc3c2CC1 +NCc1ccc(C(=O)Nc2ccncc2F)cc1-c1cccc(C(=O)Nc2ccc(C(=O)O)cc2)c1 +c1cc(-c2ccc(Cc3ccc(OCC4CCCCN4)cc3)cc2)cs1 +CN(CCCNC(=O)c1cccc2nc3ccccc3nc12)CCCNC(=O)c1cccc2nc3ccccc3nc12 +N#Cc1ccc(Cn2cncc2CN(Cc2cccc(F)c2)c2ccc(N3CCN(C(=O)c4ccc(Cl)s4)CC3)cc2)cc1 +COc1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cc(Cn3c(=O)[nH]c(=O)c4ccccc43)cnc2F)C1 +CCOC(=O)N1CCC(c2cc(O)n3nc(C)c(-c4ccc(F)cc4)c3n2)CC1 +Cc1cc(C)cc(Cc2cc(C)ccc2OCCn2ccc(=O)[nH]c2=O)c1 +COC(=O)C(NC(=O)c1cc(-c2ccccc2F)nc2ccccc12)c1ccccc1 +COc1cc(-c2nnc3n2CCCN3Cc2ccc(F)c(F)c2)ccc1-n1cnc(C)c1 +Cc1cc(OC2CN(C(=O)c3nnc(-c4ccccc4)o3)C2)ccc1CN1CC2(CCCO2)C1 +O=C1c2ccccc2C(=O)c2c1c(NCCNCCO)c1ccoc1c2NCCNCCO +CC(c1ccc(Cl)c(F)c1)n1c2c(c3cc(F)cc(S(C)(=O)=O)c31)CCCC2CC(=O)O +O=c1n(-c2ccccc2)nc2c(NCCCc3ccccc3)nc3ccccc3n12 +Cn1cccc1C(=O)N1CCN(C(=O)Nc2ccc(N3CCC(C(=O)N4CCCCC4)CC3)cc2)CC1 +Cc1nc(NC(C)c2cccc(-c3ccc(F)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +C[N+](C)(C)Cc1c2n(c3ccccc13)Cc1c(C[N+](C)(C)C)c3ccccc3n1C2 +CC1CC(=O)NN=C1c1ccc2c(c1)C(C)(C)C(=O)N2C +CN(C)c1ccnc2sc3c(=O)n(-c4ccc(C(F)(F)F)cc4)cnc3c12 +COc1cc(Nc2nccc(-c3ccc(N4CCNCC4)nc3)n2)cc(OC)c1OC +CCC(C(=O)NCc1ccc(OC)c(OC)c1)n1nc(C)c2c(C)n(-c3ccc(C)cc3)nc2c1=O +Fc1ccc(C(OC2CC3CCC(C2)N3CCCCc2ccc(N=C=S)cc2)c2ccc(F)cc2)cc1 +CNS(=O)(=O)c1ccc(-n2nc(C(N)=O)c3ccc4[nH]ncc4c32)cc1 +CC1CCC2C(C)C(OCc3ccc(CN4CCN(Cc5ccccc5)CC4)cc3)OC3OC4(C)CCC1C32OO4 +Nc1ncnc2c1ncn2C1OC(C(CSCCC(N)C(=O)O)OP(=O)(O)OP(=O)(O)NP(=O)(O)O)C(O)C1O +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Cc2ccc(F)cc2)N2C1=NC1CCCC12 +Cc1c(C(=O)C2C(C)(C)C2(C)C)c2ccccc2n1CCN1CCOCC1 +Clc1cc2nc(C3CCCN3c3cc(N4CCCCC4)ncn3)[nH]c2cc1Cl +CNC(=O)C1CCC(NC(=O)c2cnc(-n3ccc4cc(C#N)cnc43)cc2CCC(C)(C)O)CC1 +COc1cccc2c1OC(c1ccc(OCCCN3CCCCC3)cc1)C(C)S2(=O)=O +c1ccc(-c2nc(SCCCn3cccn3)[nH]c2-c2ccccc2)cc1 +Fc1ccc(-c2nn3cc(Cl)ccc3c2-c2ccncc2)cc1 +CCC1CN(c2ncc(C(=O)NC)nc2C)CCN1C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +CC(C)S(=O)(=O)c1ccc2cc1Nc1nc(ncc1Cl)Nc1ccc(N3CCN(C)CC3)c(c1)CC2 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(CC#N)cc4)cc3)cc2n(CCC)c1=O +Cc1onc(C(=O)N2CCN(C(c3ccccc3)c3ccccc3)CC2)c1[N+](=O)[O-] +Fc1ccc(C2CC3CCC(N3)C2COc2ccc3c(c2)OCO3)cc1 +COc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CC2)[nH]1 +Cc1nc(-c2ccc(S(N)(=O)=O)cc2)c(-c2ccccc2)s1 +CCCn1c(=O)c2[nH]c(-c3cc(C)n(CC(=O)Nc4ccc(OC)c(OC)c4)n3)nc2n(CCC)c1=O +Nc1ncc(-c2cc(C3C4CN(C5COC5)CC43)n(CC3CCC3)n2)cc1OC(F)F +CC(=O)OC1CCC2(C)C(CCC3(C)C2C(=O)C=C2C4CC(C)(NC(N)=O)CCC4(C)CCC23C)C1(C)C +C=CCc1c(C(=O)c2c(C)cc(C)cc2C)nc(C)nc1N(CCC)CC1CC1 +CCCCCCCCN=C1SCC2C(O)C(O)C(O)C(O)N12 +COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1cncn1 +CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)n2nc(-c3ccccc3)cc12 +NC(=O)Nc1cccc2c1C(=O)c1c(C3CCCCC3)n[nH]c1-2 +Cc1c(COc2ccccc2-c2csc(N3CCC4(C(=O)O)CC4C3)n2)ccc2c1CCN(C1CCOCC1)C2 +COc1ccccc1-c1ccc(CC(NC(=O)C2(C)CCCO2)C(=O)O)cc1 +COc1cc(CC(=O)NC(CC(C)C)c2cc(CCC(=O)O)on2)ccc1NC(=O)Nc1ccccc1C +CCOc1cc(C2CC(=O)NC3=C2C(=O)CC(c2cc(OC)ccc2OC)C3)ccc1O +CNC(=O)Cc1ccccc1Oc1nc(Nc2ccc(C(=O)NC3CCN(C)CC3)cc2OC)ncc1C(F)(F)F +CC(=O)NC1C(N)C(CC=Cc2ccc(C)cc2)=C(C(=O)O)OC1C(O)C(O)CO +COc1ccc(OC2CCN(c3nc4cnncc4nc3NC3CC3)CC2)c(F)c1 +CCN1C(=O)C(=Cc2cn(C)c3ccccc23)C(=O)N(CC)C1=S +c1ccc(SCc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1 +Cc1cc2c(OCC(O)CN3CCC(c4cc5cccc(F)c5s4)CC3C)cccc2[nH]1 +FC(F)(Cl)c1nn2cc(-c3cc4ccccc4o3)nc2s1 +Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)CCC(=O)O)O2)c(=O)[nH]c1=O +O=C(NC(=S)Nc1ccc(F)cc1)c1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +CCCC1CC(=O)C2=C(C1)NC(C)=C(C(=O)OCC)C2c1ccc(C(C)(C)C)cc1 +CC1CC(N)CN(c2ccncc2NC(=O)c2csc(C3CCCCC3)n2)C1 +Cc1ccnc2c1C(=NN=C(N)N)CC(c1sccc1Cl)C2 +CCc1ccc(C2CC(NC(=O)c3ccc(-c4cccc(C(F)(F)F)c4)cn3)CN(C(=O)C3CCCC3)C2)cc1 +C=C(c1ccc([Se]C)cc1)c1cc(OC)c(OC)c(OC)c1 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCC1CCCCN1C=O +COCCNc1nc2ccc(C#CC3(O)CCCCC3)cc2n1-c1ccnc(N)n1 +CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(CN5CCOCC5)c4)nc3c2)ccn1 +COc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C(C)C)cc4)CC3)c2cc1OC +N#Cc1nccc(N2CC(S(=O)(=O)c3ccccc3C(F)(F)F)CC2C(=O)N2CCC2)n1 +CCc1cnc(NC2CCC(NC(=O)c3ccc(F)c(F)c3)CC2)nc1N(C)C +COc1cncc(-c2ccc3c(c2)C2(COC(N)=N2)c2cc(OCC(C)(C)C)ccc2O3)c1 +CCCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccc(F)cc2OC)cc1 +Nc1nc(N)c2nc(CN3CCSc4cc(C(=O)NC(CCC(=O)O)C(=O)O)ccc43)cnc2n1 +C(=C1CCCN=C1c1cccnc1)c1cc2ccccc2o1 +Cc1ccc(NCC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)nc1 +Cc1ccc(NC(=O)c2ccsc2)cc1Nc1ccc2c(c1)CCCCC2=O +N#CC1CC2CCCC2N1C(=O)CC(N)Cc1ccc(F)cc1 +O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1cccc(Cl)c1 +CCCCCn1c(NC(=O)c2cccc(C#N)c2)nc2cc(C(=O)N3CCCCC3)cnc21 +CC1(C)c2[nH]nc(NC(=O)c3ccccc3)c2CN1C(=O)N1CCN2CCCC2C1 +CCOc1ccc(S(=O)(=O)N(CC(=O)N2Cc3ccccc3CC2C(N)=O)c2ccc(OC)cc2)cc1 +COc1ccc(COc2ccc(C=C3SC(=O)NC3=O)cc2)cc1 +COc1ccc(-c2cc(-c3ccnn3CC(F)(F)F)c3c(N)ncnn23)cc1N1CCOC(C)(C)C1=O +Cc1ccc(-n2nc(C3CCN(CC(F)(F)F)CC3)cc2NC(=O)c2cnn3cccnc23)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NC3CCCCC3)c2cn1)c1ccccc1 +COc1ccc(C(C(=O)NCCC(c2ccccc2)c2ccccc2)c2ccccc2)cc1 +CNC(=O)c1c(N)n(C2CCOCC2)c2nc(C#CC(C)(O)COC)ccc2c1=O +O=C(O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C3CC3)n3c2CCCC3)c(F)c1 +COc1cc(N2CCN(C(=O)c3ccccn3)CC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +O=C(c1cnccc1Oc1ccccc1)N1CCN(C2CC2)c2ccccc21 +CC(C)=CCCC(C)=CCCC(C)=CCCP(=O)(O)CP(=O)(O)O +N#Cc1cc(S(=O)(=O)Nc2cscn2)ccc1Oc1ccc(C(F)(F)F)cc1-c1ccnn1C1CNC1 +CN1C2COCC1CC(OC(=O)c1cn(-c3cn[nH]c3)c3ccccc13)C2 +CCCCCCCCCCCCOC(=O)c1cc(O)c(O)c(O)c1 +Cc1ccc(S(=O)(=O)Nn2c(=S)[nH]c3ccc(F)cc3c2=O)cc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCCc1[nH]c(=O)cnc1C +Cn1c2ccccc2c2nnc(SCCCn3c(=O)[nH]c4ccccc43)nc21 +CCCCN(CC)CCNC(=O)C1c2ccccc2C(=O)N(Cc2ccc(F)cc2)C1c1ccc(OC)cc1 +COc1ccc(Cl)c(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)c1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(C(C)CNCc3ccccc3C)c2=O)c1F +CC1(C)OCC2=NC3=C(C(=O)COC3)C(c3ccc(F)c(Br)c3)C2=C1O +COC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc(C23CC4CC(CC(C4)C2)C3)c2ccccc2n1 +c1ccc(-c2nnc3c4c(c(OCc5ncccn5)nn23)C2CCC4CC2)cc1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(C3CC4CN(C(=O)c5ncco5)CC4C3)nc21 +CCCCc1ccc(C(=O)c2c(C)n(CCC)c3ccccc23)c2ccccc12 +N#Cc1cccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CC(N)CC4)c2)c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCCF)s4)nc23)N1 +CC(C)(C)n1cc(-c2cc(CO)c3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +CNc1cccc(CNCC2(F)CCN(C(=O)c3ccc(F)c(Cl)c3)CC2)n1 +Cc1cc(-c2cnc(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)nc2)ccc1Cl +O=C1c2cc(N3CCCC3)ccc2NC(Cc2ccccc2)N1c1ccc(O)cc1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCCC(=O)N1CCN(C)CC1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccncc2[nH]1)C1CCCC1 +C=CC[n+]1ccc2c(c1)[nH]c1ccc(Cl)cc12 +COc1ccc2ccc(CC(O)C=CC3CCC(=O)C3CCc3ccc(C(=O)O)cc3)cc2c1 +CCC12CC(O)C(c3ccccc3)CC1CCc1cc(O)ccc12 +NC1(Cc2c(Cl)cccc2Cl)CCN(c2ncnc3[nH]ccc23)CC1 +Cc1onc(-c2ccccc2Cl)c1C(=O)Nc1sc2c(c1C#N)CCC2 +NS(=O)(=O)Nc1cncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)c1 +C#CCOC(=O)CC1C(C(=O)OCC#C)=C(N)Oc2ccc(-c3ccc(N)cc3)cc21 +COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCn2nccn2)CC1 +O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCN(c1nc3cc(Cl)ccc3o1)CC2 +O=C(NC1CCC(CNc2cncc(F)c2)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(F)c3)cc12 +CCN(CC)CCCCNc1nnc(-c2ccc(NC(=O)c3ccccc3F)cc2)o1 +Cc1cc(=O)n(-c2ccc(Cl)cc2Cl)nc1C(=O)Nc1ccc(Oc2ccnc3c2ccn3C)cc1 +Cc1cn(CC(N)C(=O)O)c(=O)n(Cc2cc(-c3ccccc3)sc2C(=O)O)c1=O +CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(-c2ccc(F)cc2)c2ccccc2c(=O)n1C +Cc1cnc(C(=O)CCN(Cc2ccccc2)C(C)C)s1 +Cc1cccc(Nc2ncnc3ccc(NC(=S)NCc4ccccc4)cc23)c1 +CCCCn1c(=O)c2c(ncn2S(=O)(=O)c2cc(C)c(Cl)cc2C)n(CCCC)c1=O 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+CCN(CC)CCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccn(Cc2ccc(Cl)cc2)c(=O)c1 +O=C(O)CCCC=CCC1C(NS(=O)(=O)c2ccccc2)CC2CC21 +COC(=O)Cc1cccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)c1 +N#CC1(NC(=O)C(Cc2ccc(Cl)c(Cl)c2)NC(=O)c2cnn(C3CCC3)n2)CC1 +CC(C)CC(NC(=O)c1cc[nH]n1)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1 +COCc1nnc(N2CC(Oc3ccc(F)cc3C)C2)n1-c1ccc(OC)nc1 +Oc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1CN1CCN(c2nc3ccccc3s2)CC1 +CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nccn5c4)c3c2)CCC1C1CC1 +CC(C)=CCCC(C)=CCCC(C)=CCN=CN(C)CCC=C(C)CCC=C(C)C +C=CC(=O)Nc1cccc(Oc2ncnc3[nH]cc(-c4cccnc4)c23)c1 +CCn1cc(-c2cc3c(-c4cc(C)ccn4)n[nH]c3cn2)cn1 +Cc1ccc(NC2=C(c3ccc(C(F)(F)F)cc3)C(=O)c3ccccc32)cc1F +COc1ccccc1N1CCN(CCCCn2cnc3c(cnc4ccc(C)cc43)c2=O)CC1 +CC(C)C(N)c1cccc(F)c1N1CCN(C(=O)C2CN(C(=O)C3CC3)CC2c2ccc(Cl)cc2)CC1 +CC(C)(C)C(=O)Nc1ccc(NC(=O)c2cccc(O)c2)nc1 +O=C(NCCCCCCCCNC(=O)NS(=O)(=O)c1cccc(Cl)c1)NS(=O)(=O)c1cccc(Cl)c1 +Cc1cccc(NC(=O)CSc2nnc(-c3ccoc3C)n2Cc2ccco2)c1 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+COc1ccc([N+](=O)[O-])cc1OCC1CN(Cc2ccc(Cl)cc2)CCO1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCNC13CC4CC(C)(CC(C)(C4)C1)C3)C2 +Fc1cccc(F)c1CNc1ncc(Oc2ccccc2C(F)(F)F)cn1 +Cc1noc(C)c1Cn1cc(N2C(=O)NC(=Cc3ccccc3)C2=O)cn1 +COc1cc(-c2ccc(C=CC(=O)O)cc2)cc(C23CC4CC(CC(C4)C2)C3)c1OC +O=C(O)c1ccc(S(=O)(=O)N(c2ncc3ccccc3c2C2CC2)C2CCc3cc(OC(F)(F)F)ccc32)cc1 +CCN(CC)CCOC(=O)c1ccccc1Sc1ccc(Cl)cc1 +Cc1noc(C)c1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1 +COc1ccc(C(=O)Nc2ccc(OCCN(C)C)cc2)cc1Nc1nccc(-c2cccnc2)n1 +Cn1ncnc1-c1cc(F)ccc1CNC(=O)c1nc(C2CCOC2)n(C)c(=O)c1O +Nc1nc(-c2ccccc2)cc(-c2cccc(Cl)c2)n1 +CCN(CC)CCOc1ccc(N2C(=O)C(=Nc3cccc(C(F)(F)F)c3)c3ccccc32)cc1 +O=S(=O)(C1=CC=C=C=C1)n1cc2c3c(cccc31)N1CCNCC1C2 +Cc1cccc2c(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)nc(N3CCN(C)CC3)nc12 +CCC(COc1cccc(OC)c1)OC(=O)NCc1ccccc1 +Cc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)N(C(C)C)C(C)C +CC(C)(C)c1ccc(-c2noc(-c3ccc4c(c3)CCO4)n2)cc1 +O=C(Nc1ccc(Cl)c(C(=O)N2CCCCC2)c1O)Nc1cccc(F)c1Cl 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+O=C(O)C1Nc2cc(Cl)cc(Cl)c2S(=O)(=O)N1Cc1cccc(F)c1 +COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2C)CC1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)Oc1cccc(-c2ccccc2)c1 +Cc1nc(-c2cccc(CN3C(=O)CCCC3c3cccc4c3OCCO4)c2)cs1 +Cc1nc(NCc2ccccc2F)cc(-c2ccc3ncsc3c2)n1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCCOc3ccccc3)[nH]c3ccc(Cl)c(F)c23)c1 +CN(C(=O)C(Cc1ccc(C(N)NN)cc1)NS(=O)(=O)c1ccc2ccccc2c1)C1CC1 +COC(=O)C1CC2CC1CN2CCOc1ccc(Cc2ccccc2)cc1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(nnc2-c2cnccn2)C1 +Cc1nsc(-c2ccc(N3CCN(c4ccccc4C(F)(F)F)CC3)nn2)n1 +O=C1NC(=O)c2c1c1c3cccc(O)c3[nH]c1c1c2c2cccc(O)c2n1C1OC(CO)C(O)C(O)C1O +Cc1cc(SC2=C(O)OC(C)(CCc3ccc(O)cc3)CC2=O)c(C(C)(C)C)cc1O +Cc1csc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c1Cl +O=C(NCCN1CCC2(CC1)C(=O)NCN2c1cccc(F)c1)c1ccc(Br)cc1 +C=CCc1cccc(C=NNC(=O)CN2CCN(Cc3ccc(F)cc3)CC2)c1O +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(F)F)nn12 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1c(-c2c(Cl)cccc2Cl)noc1C +CC(=O)C(=Nc1cccc(F)c1)NNc1ccccc1C(F)(F)F +COc1ccc(Br)cc1CCc1c(F)cccc1C(=O)N=C(N)NCC(C)C +O=C(O)c1ccccc1NC(=O)N1CC2C=C(c3ccccc3C(F)(F)F)CC2C1 +N=C(N)c1ccc2[nH]c(-c3cccc(-c4cc(CNC(N)=O)ccc4O)c3O)nc2c1 +COc1ccc(CC(C)(C)NCC(O)COc2ccc(-c3nc(-c4cccs4)c[nH]3)cc2)cc1OC +O=C(Cc1cccc(Cl)c1)NCCCNc1nc2ccccc2[nH]1 +Cc1cccc(Cl)c1Nc1nc2cc(N3CCOCC3)ccc2n2cncc12 +CC(=O)N1CCC(n2cnc3ccc(-c4cccc(OCC(O)CN5CCc6ccccc6C5)c4)cc32)CC1 +O=C(NCC(=O)N1CCC(NC2CCC(O)(c3ccc(-c4ccncc4)cn3)CC2)C1)c1cccc(C(F)(F)F)c1 +CCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +Cc1ccc(C)c(NC(S)=NCC(c2ccccc2)N(C)C)c1 +Cc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)ccc1-c1ccco1 +Cn1cc(NS(=O)(=O)c2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)cn1 +Cc1[nH]c2ccccc2c1CC(=O)Nc1cncc(C(=O)c2cn(C(C)C)c3ncncc23)c1 +CC(C)(C)NC(=O)C1CCCN1C(=O)C(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1 +COc1ccccc1CN(C)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2C)c(O)cc1O +CCN(CC(C)O)c1ccc(Br)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12 +O=C(N1CCc2ccccc21)C12CC3CC(CC(O)(C3)C1)C2 +COc1c(C)cc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1Cl +CCCCCS(=O)(=O)NC(=O)C(C)=Cc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl +CC(C)Oc1cc2c(-c3cc(N4CCC(N(C)C)C4)ncn3)n[nH]c2cc1F +CCCCN1CCCC1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC +NC(=O)c1cnc(NC2CCCNC2)c2nc(-c3ccc4ccccc4c3)cn12 +O=C(c1ccc(Cl)cc1Cl)N1CCc2c(nnn2-c2ncccn2)C1 +CCCN(CCC)C(=O)c1cc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)CNCc2cccc(OC)c2)cc(C(C)N)c1 +CC(C)n1c(=O)c(C(=O)NC2CC3CCC(C2)N3CCCCCCCCS(=O)(=O)O)cc2ccccc21 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C(C)O +O=C(NC1CCNC1)c1cn2ccnc2c(N2CCN(c3ccccn3)CC2)n1 +O=S(=O)(Nc1cc(Sc2nc[nH]n2)c(O)c2ccccc12)c1ccc(Br)cc1 +COc1ccc(S(=O)(=O)C(CC(=O)NO)c2cccc(OCc3ccccc3)c2)cc1OC1CCCC1 +Cn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(Cl)c2)CC3)n1 +COc1ccc(C(O)c2ccnc(Nc3ccc(C#N)cc3)n2)cc1 +CC(C)(COc1ccc(-c2ccc(-c3ncc(C4CCCCC4)[nH]3)cn2)cc1)C(=O)O +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1cccc(-c2ccccc2)c1 +CS(=O)(=O)c1ccc2nc(NC(=O)NCc3nc(-c4ccccc4)c[nH]3)sc2c1 +Cc1ccc(-c2cc(C(=O)NC(C)CN3CCOCC3)cc(-c3scnc3C)c2)cc1 +CNC(C)C(=O)Nc1cc(-c2ccncc2)c(-c2cncnc2)c(C#Cc2ccccc2)n1 +FC(F)(F)c1ccccc1Cn1nnc2c(NC3CC3)nc(-c3ccccc3)nc21 +CC(=O)Nc1cccc(N2CCN(CCCCNS(=O)(=O)c3ccc(C)cc3)CC2)c1 +Cc1ncncc1-c1cc(C(=O)Nc2ccc(OC(F)(F)Cl)cc2)ccc1N1CC(O)C(O)C1 +COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccccn4)cc13)CC2 +CCc1ccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC(C)N(C4CCOCC4)CC2C)C3(C)C)nc1 +CN(C)CCNC(=O)c1cccc2ccc(-c3ccc(Br)cc3)nc12 +N#Cc1ccc(Cc2ccc3c(NCCCNCc4ccco4)ccnc3c2)cc1 +O=C(O)c1cncc(-c2ccc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2)c1 +O=C(O)CSc1ncnc2c(C3CC3)c(C(F)(F)F)sc12 +O=c1cc(N2CCOCC2)oc2c3c(ccc12)CCCC3 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cnc(NC2CCN(C)CC2)nc1 +Cc1nonc1C(=O)Nc1n[nH]c2c1CN(C(=O)N1CC(C)N(CC3CCOCC3)CC1C)C2(C)C +COc1ccc2[nH]cc(CCn3cc(NC(=O)c4ncsc4-c4cccc(C)c4)cn3)c2c1 +Cc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2N(C)C)[nH]1 +CC(C(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NCCN(C(C)C)C(C)C)c1ccccc1 +Clc1cccc(COc2nc(N3CCNCC3)nc3[nH]cnc23)c1 +Cc1ccc(-n2nc(C3CCN(CC(N)=O)CC3)cc2NC(=O)c2cnn3cc(Br)cnc23)cc1 +CCc1cnc(Nc2cccc(S(N)(=O)=O)c2)nc1-c1sc(NC)nc1C +CN(c1ncnc2[nH]ccc12)C1CC(CS(=O)(=O)c2ccccc2)C1 +NC(=O)N1CCC(n2c(=O)cnc3cnc4ccc(-c5ccc(N)nc5)cc4c32)CC1 +NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ncnc3ccccc23)CC1 +O=C1NCC(c2ccc(C(F)(F)F)cc2)C12CCN(C1(c3ccc(F)cc3)CCCCC1)CC2 +O=C(O)C=Cc1ccc(Oc2c(-c3ccccc3)c(C3CC3)cc3cc(O)ccc23)cc1 +CN(c1ccccc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 +O=C(OC1CC2(N3CCCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2)c1cccnc1 +CCCCC1OC2(CCCC3=Cc4c(cnn4-c4ccc(F)cc4)CC32C)OC1CCCC +COc1nc(-c2ccccc2F)cc2nc(-c3c(Cl)c(C(C)(C)C)nn3C)[nH]c12 +CCc1ccc2c(c1)C(C(S)=NC)=CC(C)(C)O2 +NC(Cc1ccccc1)C(=O)N1Cc2ccccc2CC1c1nc(-c2ccccc2)c[nH]1 +CNCc1cc(-c2ccccc2C#N)n(S(=O)(=O)c2cccnc2)c1 +CC(=O)c1cccc(NC(=O)NCCCC2CC(Cc3ccc(F)cc3)CCN2C)c1 +O=C(c1n[nH]c2c1CCN(CC1CC1)C2)N1CCC(c2cccc(F)c2Cl)CC1 +COc1cc(Cn2c(N)nc3cc(-c4cnn(C)c4)cnc32)ccc1OCc1ccc(C(F)(F)F)nc1 +Cc1cc(NC(=O)c2ccc(CO)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C +O=C(NCc1cccnc1)Nc1ccc(S(=O)(=O)N2C3CCC2COC3)cc1 +Cc1cc(COc2ccc(C(=O)NC3CN(S(C)(=O)=O)CC3C(=O)NO)cc2)c2ccccc2n1 +FC(F)(F)c1cccc(-c2[nH]c(N3CCN(c4ncccc4C(F)(F)F)CC3)nc2-c2ccccc2)c1 +O=C(CCc1cnn(-c2ccccc2)c1)Nc1ccccc1C(=O)O +Cc1ccn2c(C(=O)Nc3cc(-c4noc(C5CC(O)(C(F)(F)F)C5)n4)ccc3C)cnc2c1 +Cc1n[nH]c(C)c1CCCOc1cc(C(=O)O)ccc1F +O=C(O)C1CC2CC(Oc3cc(-c4cccs4)ccc3-c3nnn[nH]3)CCC2CN1 +Nc1ncnc2cc(CN3C(=O)CN(S(=O)(=O)c4cc5ccc(Cl)cc5s4)CC3C(=O)O)ccc12 +COc1ccc(NC(=O)COc2ccc(C=C3N=C(c4ccccc4)N(c4ccc(OC)cc4)C3=O)cc2)cc1 +Cc1nn(C)c2nnc(Nc3ccc(S(=O)(=O)NCCO)cc3)nc12 +Cc1cc2c(Cl)cccc2nc1N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(C(=O)O)cc1 +O=[N+]([O-])c1ccc(O)c(C=NNc2ccccn2)c1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCCCC1CNCCCc1ccccc1 +Cc1ccc(OCCNC(=O)C(CC(=O)O)NC(=O)CCCOc2ccc(C(=N)N)cc2)cc1C +COc1cc2nccc(Oc3ccc(Nc4ccc(C(C)C)cc4)cc3)c2cc1OC +CC(=O)Nc1nc2ccc(-c3ccnc(Cc4ccccc4)n3)cc2s1 +CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(S(=O)(=O)Nc4ccc(OCCCC5CCCCC5)cc4F)cc3C2)cc1 +COc1ccccc1NC(=O)c1ccc(-c2cc(-c3nnc(C)o3)ccc2C)cc1 +O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2c(c1)OCO2 +N#CCNC(=O)c1cccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)c1 +NC(=S)NN=Cc1ccc(-c2ccc(SC(F)F)cc2)o1 +C=C(Br)C(=O)Nc1cccc(C=CC(=O)Nc2ccc(Cl)cc2)c1 +COC(=O)C(NC(=O)Nc1cc2[nH]nc(OC)c2c(CO)n1)c1ccccn1 +CCc1cc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)c(Cl)c2)c2c(n1)CCCC2 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(OCC4(C)CC4)ncc3F)C2)cc1 +Cc1ccccc1CN(c1ccc(C#N)c(Cl)c1)C1CCN(S(C)(=O)=O)C1 +COc1c(CN2CCC(C(=O)NC(C)(C)C)CC2)cccc1NC(=O)c1ccc(F)cc1 +CCn1c2ccccc2c2c3c(c4c5ccccc5n(CC)c4c21)C(=O)NC3 +COc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C)nc2C(C)O)n1 +O=C(O)CN1C(=O)C(NC(=O)C(S)Cc2ccccc2)CSc2ccccc21 +Cc1c[nH]c2c(-c3c(F)cc4c(c3F)C(=NOC(C)C)CC(C)(C)N4)cccc12 +Cc1ccc(C(=O)NC2(C(=O)NC(C)c3ccc(-n4nc(Cl)c5ccccc54)cc3F)CC2)cn1 +CC(=O)OC1CC2CCC1C(N(C)C)C2c1ccccc1 +COc1cccc(N2CCN(CCCn3cnc4c(cnc5ccccc54)c3=O)CC2)c1 +O=c1[nH]c(=O)n(COC(CO)CO)cc1Cc1cccc(Oc2cccc(Cl)c2)c1 +CCCCCCCCCCCC(=O)OC1=C(C)C2(OCCO2)C(=O)C2=C1N1CC3NC3C1(OC)C2COC(N)=O +CCc1ncnc(-c2ccc(C(=O)N3CCC(N4CCC(C)CC4)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +C=CC(=O)Nc1cccc(-n2c(=O)cc(C)c3cnc(Nc4ccc(N5CCN(C)CC5)cc4C)nc32)c1 +CC(c1c(F)cc2ncc(-c3cnn(C)c3)cc2c1F)n1nnc2ncc(-c3cnn(CCO)c3)nc21 +CNCC(=O)Nc1ccc(S(=O)(=O)N=c2sc(S(N)(=O)=O)nn2C)cc1 +CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3cccc(Br)n3)c2)CC1 +Cc1cc(C)c2ccn(-c3ccc(C(C)C)cc3Br)c2n1 +Oc1ccc2[nH]c(-c3ccccc3)nc2c1CNC1CCCC1 +COc1ccc(C2CC(=O)C3=C(C2)NC(C)=C(C(=O)OC2CCCC2)C3c2ccccc2F)cc1OC +COc1ccc(-c2cnc(C(=O)N3CCCC3)o2)cc1S(N)(=O)=O +CNc1ccc(C=Cc2ccc(OCCCCCCCCCCF)cc2)cc1 +Nc1ncnc2c1c(COc1cccc(Cl)c1)nn2C1CCOCC1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2cc(CC(C)C)sc2S(=O)(=O)NC(=O)OCCC2CCCC2)cc1 +COC(=O)c1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3ccccc3n(CCC(C)C)c1=O)N2 +Nc1cc(C(=O)N2CCCC2)cn2nc(-c3ccccn3)nc12 +CCOc1cc(F)c(Cn2nc(-c3ncc(OCC4(CO)COC4)c(Nc4ccncc4)n3)c3c2CCC3)c(F)c1 +N#Cc1cnc2sc(C=CC(=O)N3CCCC3)cc2c1Nc1ccc2[nH]ccc2c1 +CCC(O)(c1nnnn1Cc1ccc2c(-c3ccc(F)cc3)cc(C(N)=O)nc2c1)C(F)(F)F +CC(O)C(NC(=O)c1ccc(OCc2ccccc2)cc1)C(=O)NC(CCc1ccccc1)C(=O)NCc1cccc(Cl)c1 +CNC(=O)C(NC(=O)C(CCCc1ccccc1)C(C)N(O)C=O)C(C)(C)C +Cc1cc(-c2nc(C(F)(F)F)cn2-c2ccc(S(C)(=O)=O)cc2)ccc1F +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCCCCCCCC(=O)O)C(=O)O)cc1 +CC(=Cc1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CO2 +O=C(O)c1c(NS(=O)(=O)c2ccccc2NCCC2CCCN2C2CCCCC2)ccc2c1CCCC2 +Fc1ccccc1-c1c[nH]c(C2Cc3c([nH]c4ccccc34)C(C3CCOCC3)N2)n1 +Nc1ncc(C2=CCOCC2)nc1-c1ccc(C(=O)NC(CO)c2cccc(Cl)c2)c(F)c1 +CNc1c2ccccc2nc2cccc([N+](=O)[O-])c12 +C[N+](C)(Cc1ccc(I)cc1)CC1C2CC3CC(C2)CC1C3 +Cc1cc(C(=O)N2CCN(C)CC2)ccc1NC(=O)c1csc2c(=O)[nH]cnc12 +CCCCc1ccc(C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(C=C2SC(c3cccnc3)=NC2=O)cc1 +CC1CCC(N2CCC3(CN(C(=O)c4cc5ccccc5[nH]4)c4ccccc43)C2)CN1 +CN(C)CCNC(=O)c1cccc2ccc(-c3ccncc3)nc12 +Cc1cc2nc(C(CNC(=O)c3ccc(-n4cnnc4)cc3Cl)c3ccccc3)[nH]c2cc1C +CCCN(CCC1(O)CC(NC(=O)c2ccc3ccccc3c2)C1)C1CC1c1ccccc1Cl +O=C1COC(c2ccc(-c3cc4c(cc3Cl)NCC4C(=O)O)cc2)CN1 +Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1cccs1 +Cc1ccc(S(=O)(=O)N(CCN=[N+]=[N-])C(C(=O)NO)C(C)C)cc1 +Fc1cc(C(F)(F)F)cc2c1NC(c1ccccc1)C1CCCOC21 +N=C(N)c1ccc(COc2ccccc2OCc2ccc(C(=N)N)cc2)cc1 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+Fc1ccc(-c2nc3n(c2-c2ccncc2)CCS3)cc1 +O=C(O)COc1ccc(C=Cc2n[nH]c(-c3ccccc3O)n2)cc1 +C#Cc1cc(-c2ccc(O)c(F)c2)nc2ccc(O)cc12 +CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1ccc([N+](=O)[O-])cc1 +O=c1c2cn[nH]c2c2ccc(-c3ccccc3CN3CCCNCC3)cc2n1CC(F)(F)F +Cc1ccc(NC(=O)Nc2ccc(-c3csc4ccnc(N)c34)cc2)cc1 +CC(C)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n(C3CCC(C(=O)NC4CC4)CC3)c2n1 +Fc1ccc(-c2[nH]c3nc(NCc4ccccc4)ccc3c2-c2ccncc2)cc1 +COc1ccc(CNc2cc(OCC3CC3c3ccc(OC)cn3)nn(C)c2=O)cc1 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCn3ccc4cc(Cl)ccc43)c2)c1 +O=S(=O)(NCB(O)O)c1cc2c(Cl)ccc(Cl)c2s1 +COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3cc(I)ccc3[nH]2)CC1 +O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCN(c2cccc(F)c2)CC1 +C[S+]([O-])C=Cc1ccc(-c2cnc(C(=O)CCCCCCc3ccccc3)o2)nc1 +Clc1cccc(CCNc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)c1 +CN1CCN(c2ccc(Nc3ncc4c5ccccc5n(C5CCCC5)c4n3)nc2)CC1 +COc1cc(N2CCC(Oc3ccc(N4N=C(C(F)(F)F)C(C)C4CC(=O)O)cc3)CC2)c(Cl)cn1 +COc1ccc(S(=O)(=O)NC2CCCCN(CC(=O)CC3CCN(C(=N)N)CC3)C2=O)cc1OC +O=C(c1ccncc1)c1cc(Br)ccc1NS(=O)(=O)c1ccc(OC(F)(F)F)cc1 +O=C(c1ccc(C(=O)N2CCC(N3CCC3)CC2)cc1)N1CCC(N2CCC2)CC1 +CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1 +CN(C)C(=O)CC1CNC(C(=O)N2CCCC2C#N)C1 +N=C(N)c1ccc(OC(=O)c2ccc(CC3(C(=O)NC(CC(=O)O)C(=O)O)CCCC3)s2)c(F)c1 +O=C(CN1CCN(Cc2ccc(Cl)cc2)CC1)N1CCc2ccc(Cl)cc21 +N=C(N)Nc1cccc(C(=O)NNC(=O)CC(CC(=O)O)c2cc(Cl)cc(Cl)c2)c1 +N=C(NCc1cc(F)cc(F)c1)c1ccc(OC(F)(F)F)cc1 +Cc1ccc2c(-c3ccnc(Nc4ccccc4)n3)c(-c3ccc(F)cc3)nn2n1 +CS(=O)(=O)c1ccc(CSc2nc(-c3ccc(Br)cc3)c(-c3ccncc3)[nH]2)cc1 +COc1cccc(NC(=O)NC2CCCCC2CN2CCC(Cc3ccc(F)cc3)CC2)c1 +O=C(CCCCCC1NC(=O)C2CCCN2C(=O)C2CCOCCCCOCCC(NC1=O)C(=O)N2)NO +CCCOCC1(O)CC2CN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1 +CCCCNc1nn2c(-c3ccccc3)nnc2c2ccccc12 +COc1c(C(=O)CCc2ccccc2)c(O)c(OC)c2occc12 +OC1CCCC1n1c2cnccc2c2cnc(Nc3ccc(N4CCNCC4)nn3)nc21 +CNC(=O)c1c(NC(=O)c2nc(N3CCC3)cnc2Nc2cncnc2)cnn1C +CSc1ncc2cc(-c3ccccc3)c(-c3ccc(CNCCc4nc[nH]n4)cc3)nc2n1 +COc1cccc(-c2nc3c(oc4ccc(Br)cc43)c(=O)[nH]2)c1Cl +COc1cccc2c1CCC1C2CCCN1C(=O)c1cn(C)c2ccccc12 +CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(O)(O)=S)OC +COc1ccc(C(=O)N2CCN(C(=NC#N)Nc3cccc4ncccc34)CC2c2ccccc2)cc1OC +C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(NC(=O)C=CCN(C)C)cc23)c1 +N#CCC(=O)N(CC#N)CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(Nc1ccc2c(c1F)CCC(F)(F)C2O)c1cc2cc(Cl)ccc2[nH]1 +COc1ccc(S(=O)(=O)N2Cc3ccccc3CC2C(=O)NC(CCCN=C(N)N)C(=O)O)cc1OC +CCCOc1ccc2c(c1OC)CCN(Cc1ccc(C(C)NC(C)=O)cc1)C2 +O=C1N=C(NCCc2cccc(F)c2)SC1=Cc1ccc2ncccc2c1 +CC(NC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1)c1cncnc1 +CC(C)CNc1nc(C#CCN)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +COC1C(F)CN(C(=O)Cn2nc(C(N)=O)c3cnccc32)C1C(=O)NC(C)c1cccc(Cl)c1F +CCCCCCCNCC(OC1OC(CN)C(O)C1O)C1CC(O)C(n2ccc(=O)[nH]c2=O)O1 +COC(=O)c1ccc2sc3c(=O)n(CCN4CC5CCc6c(OC)cccc6C5C4)c(=O)[nH]c3c2c1 +CC(C)OC(=O)N(C)CC(Nc1ncnc2c1=CCCC=2C(N)=O)c1cccc(NC(=O)c2ccc(Br)cc2)c1 +CC(C)(O)Cn1cc(-c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)cn1 +Cc1cc2c(NC(=O)NC3CC(C)(C)Oc4cc(F)ccc43)cccc2cn1 +Clc1ccc(N2CCN3CC2CCC3C(c2ccccc2)c2ccccc2)cc1Cl +COC(=O)N1CCC(O)(Cc2cccc(C(CC#N)Nc3nc4nc(C)ccc4[nH]3)c2)CC1 +CCCCc1ccc2[nH]c(-c3ccc(CC)cc3)c(C=C(C#N)C#N)c2c1 +CS(=O)(=O)Oc1ccc2c(c1)CCC1C2CCN1CCCCNC(=O)c1ccc(-c2ccccc2)cc1 +NC(=O)c1cccc(-c2cc(OC(=O)NC3CCCCC3)ccc2OS(=O)(=O)O)c1 +C=CC(=O)N1CC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5cccc(Cl)c5)cc4)nn32)C1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCC(C(=O)NCc3ccccc3)C2)c1 +CC(C)(C)C(=O)OCc1cc(C(C)(C)C)ccc1CN=C(S)NCc1ccc(NS(C)(=O)=O)c(F)c1 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1(S(=O)(=O)C2CCCCC2)CCCC1 +OCC1OC(n2cc(-c3cccnc3)nn2)C(O)C(O)C1O +CN1CCCC(Cc2ccccc2)(c2cccc(OCCNS(=O)(=O)c3cnn(C)c3)c2)C1 +CCCOc1ccc(C(N)=O)cc1-c1nc(O)c2cc3c(cc2n1)ncn3Cc1ccc(F)cc1 +O=C(C1CCOCC1)N1CCC(Oc2ncnc3c2CN(c2cnc4ccccc4c2)CC3)C1 +Cc1ccc(F)c(NC(=O)c2cccc(Oc3ccnc4cc(C(=O)O)sc34)c2)c1 +Cc1cc(CCCC(CC(=O)NO)C(=O)NC(C(=O)NC(C)c2ccccc2)C(C)(C)C)ccc1-c1ccccc1 +CN1c2ccc(OC(=O)Nc3ccc4c(c3)OCO4)cc2C2(C)CCN(CCc3ccccc3)C12 +CCc1ccc(-n2cnc3c(sc4nccc(NCC(F)(F)F)c43)c2=O)cc1 +CN(C)c1ccc(C2CC3(C)C(CCC3[N+](=O)[O-])C3CCC4CC(C)(O)CCC4C23)cc1 +O=C1C(=Cc2ccc(OCCCCO)cc2O)Oc2c1ccc(O)c2O +COc1ccc(-n2nc(C)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)cc1 +O=C(O)CCCCCCOc1ccc2cc1COCC=CCOCc1cccc(c1)-c1ccnc(n1)N2 +COc1cc(C(=O)NCc2cc(F)cc(F)c2)ccc1-c1cn[nH]c1 +CC(NC(=O)C1CC2CC2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)C1CC1(Cl)Cl +O=C(O)Cc1cnc(C(=O)c2ccc(C(=O)Nc3ccc(Cl)cc3)cc2)c2ccccc12 +CCS(=O)(=O)Nc1cccc(Oc2cc(F)c(F)c(Nc3ccc(I)cc3F)c2C(N)=O)c1 +Cc1ccc2c(c1)CCC2NC(=O)COc1cc(C)c2c(C3CC3)nn(C)c2n1 +Cc1noc(C)c1-c1cc(C(O)(c2ncccn2)c2ccc(F)cc2F)c2nc(C3CC3)[nH]c2c1 +CC(=O)N1CCN(Cc2cn(S(=O)(=O)c3ccccc3Br)c3ccccc23)CC1 +CN(C(=O)NC1CCN(c2cccc(C#N)c2)CC1)C1CCN(S(C)(=O)=O)CC1 +COc1cc(CCN2CCN(CC(OC)c3ccc4c(c3C)COC4=O)CC2)ccc1C#N +O=C(NN1CCN(c2nc(-c3ccc4ccccc4n3)no2)CC1)C1CCC(F)(F)CC1 +NC1(C(=O)NC(CCCN2CCOCC2)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 +O=c1oc2ccccc2n1CCCCCN1CCN(c2ccccc2)CC1 +COc1ccc(C2c3nc(NC(C)C)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)c(CN(C)C(C)=O)c1 +O=C(CCCC1OOC(CCCC(=O)c2ccc(F)cc2)OO1)c1ccc(F)cc1 +O=C(NS(=O)(=O)c1ccc(Cl)cc1)c1ccc(Cl)cc1Br +O=C(CO)N1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncc2)CC1 +CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1 +COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O +CCCOCc1ccc(Cl)c(-c2nnc3c(C)nc4ccncc4n23)c1 +COc1cc(F)ccc1N1CCN(CCCNc2c(C(=O)N(C)C)c[nH]c3ccn[n+]2-3)CC1 +Cc1noc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)c1Br +CC(=O)Nc1cc(-c2cc(S(N)(=O)=O)c(C)s2)no1 +CS(=O)(=O)CC1CCC(Nc2nccc(-n3ccc4c(N5CCN(C(=O)CC#N)CC5)cccc43)n2)CC1 +COc1ccccc1-n1nc(C2CCN(S(C)(=O)=O)CC2)cc1-c1ccc(Cl)s1 +O=C(Cc1ccc(-c2ccccc2)cc1)NC1CCOC1=O +COc1cccc2c1-c1cccc3c1C(C2)N(C(C)C)CC3 +OC(CNC12CC3CC(CC(C3)C1)C2)COc1cccc2[nH]ccc12 +CCN(CCCNC(=O)CCn1c(=O)[nH]c2ccsc2c1=O)c1ccccc1 +COC1Cc2c(csc2-c2ccc(-c3ccccc3)cc2)C2(CCN(Cc3ccccc3)CC2)O1 +O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3ccc(F)cc3)CC2)nc1 +CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5cnccn45)n(C)n3)cc2C(F)(F)F)CC1 +Cc1cc(Oc2nccc3n[nH]cc23)ccc1-n1c(C)nc2cnccc21 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)NC3CCC(N)CC3)cc2F)cn1 +CNC(=O)C(C)(C(=O)NO)N(C)C(=O)c1ccc(C#Cc2ccc(CN3CC(OC)C3)cc2)cc1 +CCCCN(CCCC)CCCOc1ccc(-c2nc(-c3ccccc3)sc2CC)cc1 +O=c1ccc2cnc3ccc(-c4ccc5ccccc5c4)cc3c2n1-c1ccc(N2CCNCC2)c(C(F)(F)F)c1 +CCCCCN(CCCCC)C(=O)c1cc(-c2ccccc2)no1 +CSc1nc(NC(=O)C(c2ccccc2)c2ccccc2)n2nc(-c3ccco3)nc2n1 +COc1ccc(OCC(=O)Nc2ccc3nc(N4CCCC4)nc(C)c3c2)cc1 +CCCN1Cc2n[nH]c(=O)c3cc(F)cc4[nH]c(c2c43)C1 +COc1cc(-c2cn(C3CC(C4CCCCC4)CCNC3=O)nn2)ccc1-n1cnc(C)c1 +O=C(NN=Cc1ccc(Sc2nc3ccccc3[nH]2)o1)c1cccc([N+](=O)[O-])c1 +CC1=C(C#N)C(=O)N(C)C(=O)C1=Nc1ccc(N(C)C)cc1 +COc1cc(NS(=O)(=O)c2ccccc2)ccc1-c1cncc2ccccc12 +Cc1c(C(=O)NCC2CC3CC(C2)C3(C)C)ncn1-c1ccccc1 +O=C(CCCCCN1CCN(c2ccccc2O)CC1)NC1CCCc2ccccc21 +CCCCCCCCCCCCCCCC(=O)OCCSCC(NC(=O)C(F)(F)F)C(=O)NC(CO)C(=O)OC +N#CCCCCCc1cnc(C(=O)CCCCCCc2ccccc2)o1 +Cc1cc(NC(=O)N2CC3CC(c4ccccc4C(F)(F)F)CC3C2)c(C(=O)O)cn1 +COc1cc(Cl)c(Cl)cc1N1CCN(CCn2cnc3sc4c(c3c2=O)CCN(C)C4)CC1 +N#Cc1cc(Cl)cc(Oc2c(Br)ccn(Cc3n[nH]c4ncccc34)c2=O)c1 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+COc1cccc2c1CCN(Cc1ccc(C(C)NC(=O)C3CC3)cc1)C2 +CCCCc1c(C)c(OC)c2c(ccn2C)c1OC(C)=O +CCn1c(C)c(-c2cnc(C)nc2OCC2CC2c2ccc3ccccc3n2)ccc1=O +Cc1cc(NC2CCCC2)nc2ccc(NC(=O)COc3ccc(C(F)(F)F)cc3)cc12 +NCC(=O)NCCOc1cc(-c2ccccc2Cl)c2ccc(=O)n(-c3c(Cl)cccc3Cl)c2c1 +COc1ccc(C=C2CC(CO)(COC(=O)c3ccc([N+](=O)[O-])cc3)OC2=O)cc1 +C=C(C)C1CCC2(C(=O)OCc3ccccc3)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +COC(=O)c1ccc(N2CCN(C)CC2)cc1NCCc1ccccc1 +CNC1Cc2ccc(OCCNS(=O)(=O)c3cn(C)cn3)cc2C1Cc1ccccc1 +O=S(=O)(NCC(c1cccnc1)N1CCN(Cc2ccccc2)CC1)c1ccccc1 +CCc1cc(CCc2ccccc2)nn1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2ccccc2)CC1 +CC(=O)N(CCc1nc2ccccc2c(=O)n1-c1ccc(Cl)cc1)C(C)=O +c1cncc(CCNc2nccn3c(-c4ccc5ccccc5c4)cnc23)c1 +O=C(OCC1CCCC(c2cc(F)ccc2F)N1S(=O)(=O)c1ccc(Cl)cc1)N1CCC(N2CCCCC2)CC1 +Cc1cnc2n1-c1cc(Cl)c(Cl)cc1N=C(c1ccc(-n3c(C)nc4cnccc43)cc1)C2 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(F)(Cc2ccccc2)C1 +CC(C)CS(=O)(=O)N1CCCC(NC(=O)Nc2cnc3[nH]ccc3n2)C1 +Cc1c(N2CCCCCC2)nc(C2CC2)nc1N1CCCCCC1 +COC1CCC(NC(=O)c2n[nH]cc2NC(=O)c2ccccc2C(F)(F)F)CC1 +COc1ccc(Sc2ccc3c(c2)N=C(c2ccc(C(=O)O)cc2)c2cc4c(cc2N3C)C(C)(C)CCC4(C)C)cc1 +Nc1ncnc2c1c(-c1ccc(Nc3nc4cccc(Cl)c4o3)cc1)nn2C1CCC(N2CCOCC2)CC1 +O=C(O)C(CCC(=O)N1CCC(CCCC2CCNCC2)CC1)NS(=O)(=O)c1ccc2ccccc2c1 +COCCNc1cc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)ncc1C(F)(F)F +O=C(Cn1nnc(-c2ccccc2)n1)NN=Cc1cc([N+](=O)[O-])ccc1O +CC(O)CNc1nc(NCc2ccc(-c3ccccn3)cc2)c2[nH]nc(C(C)C)c2n1 +CCCCCCOP(=O)(O)C1=CC(C(NC(C)=O)C(CC)CC)C(NC(=N)N)C1 +CC(C)OC(=O)C1C(=O)C(=Cc2c[nH]c3ncccc23)OC1=NN1CCOCC1 +Cc1ccnc2nc(-c3cccc4ccccc34)cc(O)c12 +COc1ccc2c(c1)CN(C(=O)NCc1ccc3c(c1)CCO3)CCS2 +COc1cccc(C2=C(c3c(C)n(C)c4ccccc34)C(=O)NC2=O)c1 +Cc1nn(Cc2ccccn2)c(C)c1CC(=O)NCc1ccc(F)cc1Cl +O=C(CCCN1C(=O)c2ccccc2S1(=O)=O)Nc1ccc(C(=O)NO)cc1 +O=C1NCN(c2ccccc2)C12CCN(C1CCCCC1c1ccc(Cl)c(Cl)c1)CC2 +O=C(NC1Cc2ccccc2C1)c1cc2sc(Cl)c(Cl)c2[nH]1 +CCNC(=O)N1CCC(N2CCN(C(C)c3ccc(S(=O)(=O)c4ccc5c(c4)OCO5)cc3)C(C)C2)CC1 +N#Cc1cncc(Cc2ccc3c(c2)-c2nc(N)nc(-c4ccccc4)c2C3=O)c1 +[N-]=[N+]=Nc1ccc(S(=O)(=O)Nc2ccnn2-c2ccccc2)cc1 +O=C(Nc1cccc2ccc(O)cc12)NC1CCc2cc(F)ccc2C1Cc1ccc(C(F)(F)F)cc1 +CCCN(CCCc1ccc(F)cc1)CC(O)C(C)NC(=O)Nc1cccc(-c2nnnn2C)c1 +CC(C)CCCC(C)C1CCC2C3=CCn4c(=O)ccc(=O)n4C3CCC21C +Cc1cc(-c2ccc3c(c2)CCN(CCCSc2nnc(C(C)C)n2C)CC3)no1 +Nc1cnc(-c2ccc(C3CCC3)c(Oc3ccnc(N)n3)c2F)cn1 +O=C1NC(=O)C(CC(=O)N2CCN(c3cccc(CNC(=O)c4nc5ccccc5c(=O)[nH]4)c3)CC2)N1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CNC5)c4)ccn23)c1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1ccccc1OC(F)F +CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CC1CCCN1C +CCOC(=O)C1=C(C)NC2=C(C(=O)C(C(=O)OCC)C(c3ccccc3OC)C2)C1c1ccc(OC)c(OC)c1 +CC(C)(C)c1cc(C=Cc2ccc(F)cc2)cc(C(C)(C)C)c1O +CC(C)(C)OC(=O)NCCOc1cccc2c1cnn2-c1ccccc1F +CCCNc1nc(N(C)C)nc2c1cnn2CC(Cl)c1ccccc1 +CC(C)(C)NCc1ccc2c(c1)OCCC2NC(=O)CC(NS(=O)(=O)c1ccc(F)c(Cl)c1)c1ccccc1 +CC(C)C1SC(Nc2ccccc2C(F)(F)F)=NC1=O +O=C(NCCCCN1CCC2c3ccc(O)cc3CCC21)c1ccc(-c2ccccc2)cc1 +CCCCCCCCn1cc2c(nc(NC(=O)NCCCCC)n3nc(-c4ccco4)nc23)n1 +Oc1ccc2c3c1OC1c4c(c5ccccc5n4CCF)CC4(O)C(C2)N(CC2CC2)CCC314 +CC(C)n1cnc2c(NCc3ccc(-c4ccc(Cl)s4)cc3)nc(NC3CCC(N)CC3)nc21 +COc1cc(C(=O)NC(C)c2ccccc2F)ccc1-c1cn[nH]c1 +O=Cc1nc2c(cc1CO)CCCN2C(=O)Nc1ccc(C(F)(F)F)cn1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)Nc1cnc2ccccc2c1 +COC1C(OC(=O)NC(C(=O)NCCC2CCCN2C)C(C)C)CCC2(CO2)C1C1(C)OC1CC=C(C)C +O=C(NCc1ccc(S(=O)(=O)c2ccc(N3CCOCC3)nc2)cn1)c1cc2ccncc2s1 +NC(=O)c1cc(-c2ccnc(NC3CCCCC3)c2)nc(N2CCNCC2)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=NOCCn1c(=O)cc[nH]c1=O +O=C(Nc1ccc(Br)cc1)NC1CCC(Oc2ccc(F)cc2)CC1 +N#CCCNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +CCCOc1ccc(C(=O)NO)cc1NC(=O)c1ccccc1 +O=C(NC1CCC(O)CC1)NC12CC3CC(CC(C3)C1)C2 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OC(F)F)cc2)cs1 +COc1cc(Nc2nccc(Nc3cc(C)[nH]n3)n2)ccc1-c1nc2ccccc2s1 +O=C(CCC(F)(F)F)N1CCC(c2nc(-c3ccccc3)no2)CC1 +Cn1cc(-c2ccc(N3CCC(N4CCc5ccccc54)CC3)nn2)cn1 +O=C(NO)c1ccc(N2CCN(CCCN3CCOCC3)C2=O)cc1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3cncc(Cl)c3)c2)c2cncnc21 +Cn1cnc(-c2cc3nccc(Oc4ccc(NC(CC(=O)Nc5ccc(F)cc5)C(F)(F)F)cc4F)c3s2)c1 +CCN1C(=O)c2nc(-c3ccc(C#N)c(F)c3)n(Cc3ccc(F)c(F)c3)c2N2CC(C(C)C)N=C12 +Clc1ccc(Nc2nc(N3CCNCC3)nc3ccccc23)cc1 +Cc1cccc(C)c1Nc1ccc(C(=O)NCCCCCCC(=O)NO)cc1F +CC1(CC(=O)NCc2ccc([N+](=O)[O-])cc2)CC2(CCCCC2)OO1 +Cc1ccc(N2CCc3ncnc(NC(CO)c4cnc(C)nc4)c3C2)c(C#N)c1 +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccccc2o1 +O=C(NCc1cncc2ccccc12)N1C(=O)OC(c2cccc(C(F)(F)F)c2)C1CO +O=C(O)Cc1sc(C2COc3ccccc3O2)nc1-c1ccc(Cl)cc1 +COCCCn1c(NC(=O)c2cccc(C#N)c2)nc2cc(C(=O)N3CCCCC3)ccc21 +O=C(N1CCN(c2ccccc2[N+](=O)[O-])CC1)n1nnc2ccccc21 +COc1ccc(-c2cnc(C3CCC3)o2)cc1S(N)(=O)=O +CN(C)CCn1c(=O)c2ccc(NCCNCCO)c3c(=O)c4cc(O)ccc4n(c1=O)c23 +COCCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 +O=[N+]([O-])c1cc2c(OCCC3CCCCN3)c(-c3ccsc3)c(O)nc2cc1Cl +CC(C)=CCCC(C)=CCCC(=CCOP(=O)(O)OP(=O)(O)O)CC(C)C +ON=C(CCN1CCN(c2ccccn2)CC1)c1ccccc1Cl +Cn1cc(C2=C(c3cn(C4CCN(Cc5ccccn5)CC4)c4ccccc34)C(=O)NC2=O)c2ccccc21 +O=C1c2ccc(S(=O)(=O)O)cc2C(=O)c2ccc(S(=O)(=O)O)cc21 +COC1CCN(c2ncc(F)c(N3CCC(Oc4ccc(C(C)NC(C)=O)cc4)C3)n2)CC1 +Cn1c(-c2ccc(-c3ccncc3)cc2Cl)nnc1C1(c2ccc(Cl)cc2)CCC1 +CCc1cccc(NC(=O)Nc2csc(-c3cc4ccccc4n3C(N)=O)c2)c1 +CCC(CC)Nc1cc(C)nc2c(-c3ccc(OC)cc3C)c(C)nn12 +N#Cc1cc(F)cc(C(=O)N2CCn3nc(COc4ccccc4)cc3C2)c1 +CCNC(=O)Cn1c(=O)n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c2ccccc21 +OCc1ccc(-c2nnc(SCCCN3CCN(c4nsc5ccccc45)CC3)o2)cc1 +CC(C)CC(NC(=O)CC(NC(=O)C1CCCCC1)c1cccc(F)c1)B(O)O +O=C(NC1CCCOC1)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CCOc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccc(N4CCOCC4)cc3)n1)CCN(CC(=O)N(C)C)CC2 +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(N(C)C(=O)NCCCC)cc3)CC21C +Fc1cccc(-c2cc(-c3cnn(C4CCNCC4)c3)on2)c1Cl +CCCC(C)COc1ccc(C(CO)NC(=O)Cc2ccccc2)cc1 +CC1CCCN1CCCOc1ccc(-c2ccc(=O)n(C)n2)cc1F +O=C(Nc1ccc(-c2cccc3sncc23)cc1)Nc1ccc(F)c(C(F)(F)F)c1 +CN1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cn5ccc(C#N)cc5n4)c3)sc2C1 +Cc1nc(S(C)(=O)=O)ccc1Nc1ncnc(OC2CCN(C(=O)OC(C)C)CC2)c1C1CC1 +Nc1ncc(-c2nc(N3CCOCC3)nc3c(CN4CCN(C(=O)CO)CC4)csc23)cn1 +CC(C)Oc1cncc(C2=CC3CC(C2)CN(C)C3)c1 +CN(C)CCNc1c2c(c(C#N)c3nc4ccccc4n13)CCCC2 +Cc1csc2c(N3CCNCC3)nc(-c3ccncc3)nc12 +CCCCCCC(C(=O)N1CC(Oc2ccccc2)CC1C(=O)O)n1cnc(NC(=O)c2ccccc2S(=O)(=O)O)c1 +N=C(N)c1ccc(CCC(CC(=O)n2cccc2)c2cccc(C(=N)N)c2)cc1 +COC1CCC(CC(=O)NC2CCC(CCN3CCN(c4nccc5occc45)CC3)CC2)C1 +COc1ccc(C(=O)NC(=S)Nc2sc3c(c2C(=O)O)CC(C)(C)OC3)cc1 +CCCCc1c(Oc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)nc2c(C(=O)O)c(N)ccc2[n+]1[O-] +CCCC(CC1CCc2c(cccc2OCC(=O)O)C1)=NOC(c1ccccc1)c1cccnc1 +CC(C)(C(=O)O)c1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1 +O=C(COc1ccc(-c2cccnc2)cc1)Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1 +COc1cccc(C(=O)Nc2cc(-n3ccn4nc(-c5cccnc5)cc34)c(C)cc2C)c1 +CC(NC(=O)N(C)C)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3F)C2)cc1 +CC(=O)N1CCC(COc2ccc3oc(-c4cc5sccc5cn4)cc(=NO)c3c2)CC1 +Clc1ccc(-c2c[nH]c(-c3nccc4ccccc34)n2)cc1Cl +CCCCNc1ccc2oc(-c3cc(-c4cnn(C5CCNCC5)c4)cnc3N)nc2c1 +O=C(NC1CCOCC1C(=O)NO)c1ccc(Cn2c(C(F)(F)F)nc3ccccc32)nc1 +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2ccc(O)cc2)C(C(=O)O)C1 +Clc1ccccc1-c1ccccc1C=NNc1c(Cl)cncc1Cl +OCC1OC(n2cc(F)c3c(-c4ccsc4)ncnc32)C(O)C1O +CCCS(=O)(=O)N1CCN(C2(CNC(=O)c3c(F)cccc3F)CCCCC2)CC1 +CCOc1ccc2c(c1)n1ncc(Cl)c1n[n+]2[O-] +CCNC(=O)OCC1OC(n2cnc3c(NC4CCOC4)ncnc32)C(O)C1O +Cc1cc(Br)cc(C)c1Oc1nc(N)nc(Nc2ccc(C#N)cc2)n1 +CC(C)=CCC12OC(C)(C)C3CC(C=C4C(=O)c5ccccc5OC431)C2=O +O=C(CCCCCCc1ccccc1)c1nc(C(=O)C(F)(F)F)co1 +CC1CCc2nc(CCCN3CC=C(c4ccccc4)CC3)[nH]c(=O)c2C1 +CC(C)NC(=O)OC1(C(=O)CO)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC21C +Cn1cc(-c2ccc3nc(NC(=O)c4cncc(-c5ccc(C#N)cc5)c4)cn3n2)c(-c2ccc(F)cc2)n1 +CCOc1cc2ncnc(Nc3ccc4c(cnn4Cc4ccccc4)c3)c2cc1NC(=O)C=CCN(C(C)C)C(C)C +O=C(Cc1ccc(Cl)c(Cl)c1)N1CCc2sccc2C1CN1CCCC1 +Cc1nc(-c2ccc(N3C(=O)c4n[nH]c(C(C)(C)C)c4C3c3ccccc3OCCO)cc2)no1 +O=C1c2ccc(C(F)(F)F)cc2OCN1CCO[N+](=O)[O-] +CCCCCNC(=O)NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Oc1ccc(C)cc1 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+Nc1nnc(-c2ccc3[nH]cc(-c4cncc(N5CCCC5)n4)c3c2)s1 +CC(NC(=O)CNC(=O)Nc1ccc(C(=N)N)cc1)c1ccc(Br)cc1 +COc1ccc(-c2nnc(NC(=O)c3ccc(C4CCC(CC(=O)O)CC4)cc3)s2)cc1 +O=C(O)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1 +CCN(CC)CCCNC(=O)c1ccc(Nc2ncc(C)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +OCC1OC(n2cnc3c(NC4CC4)ncnc32)C(O)C1O +COc1ccc(N(Nc2ccc(Br)cc2)c2ccccc2N(Nc2ccc(Br)cc2)c2ccccc2OC)cc1 +Cc1ccc2c(c1)NC(c1ccccc1[N+](=O)[O-])C1=C(CC(C)(C)CC1=O)N2 +Fc1ccc(-c2ccc3c(c2)CCC=C3c2ccncc2)cc1 +FC(F)(F)Cn1nccc1-c1ccccc1NCC1=NCCN1 +CCOc1ccc(Cc2cc(C3SC(CO)C(O)C(O)C3O)ccc2O)cc1 +Cc1nc(-n2cnn(CCCC(F)(F)F)c2=O)sc1C(=O)NCc1cccnc1 +O=C(O)CC1OCCn2c1cc1cc(OCc3ccc(OC(CF)CF)c(Cl)c3)ccc12 +COc1cccc(-c2ccc(CCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(N)=O)cc2)c1 +CCC(CC)Nc1nc(C)nc2c(-c3cnc(N(C)C)cc3C)c(C)nn12 +CCC(=O)N1CCC(CN2CCC(NC(=O)c3cc(Cl)c(N)cc3OC)C(OC)C2)CC1 +O=C(c1ccccn1)N1CC2CC34CCC1C2C31CCN(CC2CC2)C4Cc2ccc(O)cc21 +O=C(Nc1nc2ccccc2[nH]1)C12CC3CC(CC(C3)C1)C2 +Nc1cc(C(F)(F)F)nc(SCc2ccc3ccccc3c2)n1 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+CCCCCc1ccc(C(=O)N(CCCC(C)Nc2cc(OC)cc3cccnc23)Cc2ccc(OC)c(OC)c2)cc1 +CN(Cc1n[nH]c(O)n1)CC1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +CCCc1ccc(-c2onc3c2COc2cc(CN4CC(C(=O)O)C4)ccc2-3)cc1 +Cc1cc(Nc2cc(OC3CCCCC3)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1 +N#Cc1ccc(OCc2ccsc2)cc1OC(C(=O)O)c1ccsc1 +COc1ccc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +COc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C +COc1cc(C)nc2c(-c3ccc(Cl)cc3Cl)cccc12 +N#Cc1ccc(N2CC3C(C2)C3NCC(=O)N2CC(F)CC2C#N)cc1Cl +COc1cc(OC)cc(N(CCN)c2ccc3ncc(-c4cnn(CC5CCOCC5)c4)nc3c2)c1 +COc1cc(OC)cc(N(CC2COCC(C)(C)N2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CCS(=O)(=O)N1CC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +O=C(NCCO)c1ccccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +O=C(NO)c1cc2c(cc1F)CCC(NS(=O)(=O)c1cccc(Cl)c1)C2 +O=C(Nc1nnc(SCc2ccccc2)s1)c1ccccc1Cl +Cc1[nH]c(C)c(-c2ccc(OCc3ccc(OC(F)(F)F)cc3)nc2)c(=O)c1Cl +COc1ccc(S(=O)(=O)N(CCC2CCCCC2)CC(=O)NO)cc1 +Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(Cl)cc1 +O=C(NCC1C2CC3CC(C2)CC1C3)C1C2c3ccccc3C(c3ccccc32)C1C(=O)N1CCCC1C(=O)O +C=C1CCN(c2ncc(C#Cc3ccc(CC(C)NC(C)=O)cc3)cn2)CC1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(N(C)Cc3ccccc3)nc12 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CCOC4)ncc23)ccn1 +O=C1C(=O)N(Cc2ccncc2)c2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc21 +COc1c(C(=O)OCC(C)CC2=C(O)C(=O)c3ccccc3C2=O)ccc2ccccc12 +COc1ccccc1NC(=O)N1CC(C(=O)N2CCCC2)C=C2c3cccc4[nH]cc(c34)CC21 +CC(NC(=O)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1)C1CCCCC1 +CCN(C(=O)CO)C1CN(C(=NC#N)Nc2ccc3c(c2)OC(F)(F)O3)N=C1c1ccc(Cl)cc1 +CCOC(=O)C=Cc1cnc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O +CCOc1ccc(CC(NC(=O)c2cnc(Cl)c(Cl)c2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)cc2)cc1 +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CC2OC(=O)C(=C)C2CC(C)C)CC(O)CC1O +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCN(C2CCCC2)CC1 +CNS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(Cn3cnnn3)CC(c3cccc(C(=N)N)c3)=NO2)cc1 +Cc1nn(C)cc1C(=O)N1CCC2(CC1)CC2CNC(=O)N1Cc2ccncc2C1 +O=C(NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1)N1CCCC1Cc1cccnc1 +O=C1N(c2ccc(F)cn2)CCc2nc(COc3ccccc3)cn21 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cc2)cc1C#Cc1nn(C(C)C)c2ncnc(N)c12 +CNc1nc2ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc3ccccc3)NC(=O)OC3COC4OCCC34)cc2o1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(C)c2C)c1 +CC(=O)c1ccc(S(=O)(=O)Nc2cccc(-n3cnnn3)c2)cc1 +COc1cnc(-n2cnc(C)n2)c2[nH]cc(C(=O)C(=O)N3CCc4c(-c5ccccn5)cccc4C3O)c12 +CC(C)=CCC1C(=O)C(C(=O)CC(C)C)=C(O)C(O)(CC=C(C)C)C1=O +Nc1nc2c(c(=O)n(CC3CC3)c(=O)n2CC2CC2)n1S(=O)(=O)c1ccc([N+](=O)[O-])cc1 +Cc1cc(N2CCOCC2)cc2[nH]c(-c3c(NCCc4nc(C)n(C)c4Cl)cc[nH]c3=O)nc12 +COc1cc(C=Cc2ccc3ccccc3c2)cc([N+](=O)[O-])c1OC +C=CC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 +NCc1ccc(CC(CP(=O)(O)C(N)CCc2ccccc2)C(=O)O)cc1 +Fc1ccc(-c2cnc3cc(-c4ccco4)ccn23)cc1 +Cn1c(=O)c2nc(-c3ccc4ccccc4c3)[nH]c2n(C)c1=O +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)c2ccc3c(cnn3CCCNC3=NCCN3)c2)C(=O)O)c(C)c1 +COc1nccc2c3cnc(Nc4ccc(N5CCC(N6CCCC6)CC5)cn4)nc3n(C3CCC(C)(C)CC3)c12 +O=C1NCc2ccc(OCCCN3CCN(c4cccc5cc(F)ccc45)CC3)c(F)c21 +CC(O)CNC(=O)c1c[nH]c(-c2n[nH]cc2CN2CCN(c3ccc(C(F)(F)F)cn3)C(C)C2)c1 +CC1(C)CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 +CCCCCN1CC(C)C(C)(c2cccc(O)c2)CC1CCC +Nc1nc(-n2cc(CO)nn2)nc2c1ncn2C1OC(COS(=O)(=O)NC(=O)c2ccccc2O)C(O)C1O +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3ccc(Cl)cc3)o2)c1 +O=C(CN1C(=O)c2ccccc2S1(=O)=O)c1ccccc1Cl +O=C(Nc1nccc2nn(-c3c(Cl)cccc3Cl)cc12)C1CC1 +NS(=O)(=O)c1cn(CC(=O)NS(=O)(=O)c2ccc(Cl)cc2)ccc1=O +CN(C)CC(=O)NCCc1c[nH]c2ccc3c(c12)CCNC3=O +CCCCCCCCCCCCSC(=O)CS(=O)(=O)Nc1c(C(C)C)cccc1C(C)C +Cc1cccc(COc2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)c1 +O=C(NCc1cccc(-c2cccc(-c3cc4c[nH]ccc-4n3)c2O)c1)C(CO)c1ccccc1 +CN(C)C1CC2CCC(C1)N2c1ccc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)nc1 +CC1CC(N(C)C(C)C)CCC1N1CCC(Nc2ncnc3ccc(C(F)(F)F)cc23)C1=O +CCNC(=O)c1noc(-c2cc(CCc3ccc(F)cc3)c(O)cc2O)c1-c1ccc(CN2CCCCC2)cc1 +O=C(Nc1ccc2sc(CO)nc2c1)c1ccc(Cl)cc1 +CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(O)cc2)CC1 +COc1ccc2[nH]cc(C(=O)OCC34CCN(CC3)CC4)c2c1OC +Cc1ccc(N2CCc3ncnc(NC(C)c4ccc(Br)cc4)c3C2)nc1 +NC(=O)C(Cc1ccccc1)NC(=O)C(CS)NC(=O)COc1ccccc1 +Brc1c(Br)c(Br)c2[nH]c(NCC3CCNCC3)nc2c1Br +NC(=O)N1CCC(Oc2cccc3ccc(-c4nnc5ccccn45)nc23)CC1 +COC(=O)N(NC(=O)c1c(CN2CCN(C(C)C)CC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +COc1cc(Oc2c(C)cc(C#N)cc2C)cc(Nc2ccc(C#N)cc2)n1 +CCc1nc2ccc(OC3CCN(C(C)=N)CC3)cc2n1CC=Cc1ccc(N)cc1 +O=C(NCCO)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1 +CC(CCc1ccc(OC(=O)c2ccccc2)cc1)=NNC(N)=S +Cc1cc(I)ccc1Nc1c(C(=O)O)cc(F)c(F)c1F +CCCCCCCCCCCC(=O)OC1C(OC2(CO)OC(CO)C(O)C2OCC(C)C)OC(CO)C(O)C1OCC(C)C +COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3ccccc3s2)n1 +O=C(CC(NC(=O)c1ccccc1)c1cccc(Cl)c1)NC(Cc1ccc(F)cc1)B(O)O +C=CC1CN2CCC1CC2C(OCCc1cn(-c2ccc(OC)cc2)nn1)c1ccnc2ccc(OC)cc12 +COc1ccc(N2CCN(CCn3cnc4c3nc(N)n3nc(-c5ccco5)nc43)CC2)cc1 +CCOc1c(I)cc(CO)cc1CNCCCNc1cc(O)c2ccccc2n1 +CC(C)(C)OC(=O)Nc1ccc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc1 +Cn1cc2c(nc(NC(c3ccccc3)c3ccccc3)n3nc(-c4ccco4)nc23)n1 +COc1ccc2c(c1)OCCCCCOCCN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +C=C1C(=O)C23CCC4C(C)(C)C(OC(C)=O)CC(O)C4(C)C2C(OC(C)=O)CC1C3 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1cc(Cl)cc(Cl)c1 +O=S(=O)(Nc1nccs1)c1ccc2c(c1)OCCC2c1ccc(C(F)(F)F)cc1Cl +Cc1cc(C)c(C(=O)NC(Cc2ccc(N3CCC(c4ccc5c(n4)NCCC5)CC3)cc2)C(=O)O)c(C)c1 +Cc1nc2cc(-n3ncc(C(=O)c4cc5c(C)cccc5[nH]4)c3N)ccc2[nH]1 +C[N+]1(CC2CCCCC2)CCc2c(sc(NC(=O)Nc3ccc(Cl)cc3)c2C(N)=O)C1 +C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C4CC4)ncn3)CC2)c2cc[nH]c2c1=O +O=C(NO)c1ccc2c(c1)CCN(S(=O)(=O)c1ccc(C(F)(F)F)cc1)C2 +O=S(=O)(c1ccc(Cl)nc1)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1Br +Cc1csc(-c2nc(C)[nH]c2-c2ccc3ncsc3c2)n1 +NS(=O)(=O)c1cc2c(s1)[S+]([O-])CC(=O)N2 +Cc1ccc2cc(C(=O)NC3(C(=O)NC(CCCC4CCN(CC5CCOCC5)CC4)Cc4ccccc4)CCCC3)sc2c1 +Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(CO)CO)C2 +O=C1CC(c2c[nH]c3ccccc23)C(=O)N1CCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +COc1ccc(C(=O)N2CCCC(Nc3cnc(C(F)(F)F)cn3)C2C)c(-n2nccn2)c1 +Cn1cc(F)cc(C2CCCN2c2ccn3ncc(C(=O)NC4CC4)c3n2)c1=O +CC(=O)OC1CC(C(=O)O)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +COc1ccc2[nH]c(C(=O)NCCCN3CCN(c4ccccc4OC)CC3)cc2c1 +CCCN1CCC(N2CC(NCc3ccc4c(c3)c3ccccc3n4CC)CC2C(=O)NCC)CC1 +CC(C)(O)c1ccccc1-c1ccc2[nH]c(C#Cc3ccc(C(F)(F)F)cc3)nc2c1 +O=C(NC1CCCC1Nc1ccc(C(F)(F)F)cn1)c1cc(Cl)ccc1-n1nccn1 +CCCCC(NC(=O)OC(C(C)C)C(C)C)C(=O)C(=O)Nc1ccccn1 +O=C1Cc2c(OCCN3Cc4ccccc4C3)ccc(F)c2N1 +CCOc1cc(CN2CCC(Nc3nc4cc(Cl)ccc4o3)CC2)ccc1OC +CNC(=O)c1cc(-c2ncnc(C)c2C#Cc2ccc(N)nc2)ccc1F +CCN1C(=O)c2c(nc(OC)n2Cc2ccc(O)c(C#N)c2)N2CC(Cc3ccccc3)N=C12 +Nc1ncnc(N2CCN(Cc3cc(Cl)c(Cl)cc3OC3CNC3)CC2)c1-c1ccc(F)cc1 +CC(=O)C1(O)CCC2(C)C1C(O)CC1C3(C)CCC(O)C(C)(C)C3CCC12C +NC1CCC(Nc2cc(-c3cccc(NCc4ccc(OC(F)F)cc4)n3)c(Cl)cn2)CC1 +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2c(cnn2Cc2ccccc2)c1 +O=C1NC(=O)C(c2ccc(-c3ccc4ccccc4c3)[nH]c2=O)(C(F)(F)F)O1 +Cc1ccc(-n2c(C)nc3c(Nc4ccc(-c5ccncc5)cc4)ncnc32)c(C)c1 +CCC(NC(=O)c1ccc2c(ccn2C(=O)c2cccc(F)c2F)c1)c1ccccc1 +CCCN(c1ccccn1)C1CCN(CC2CN(C(=O)N3CCCC3)CC2c2ccccc2)CC1 +COc1ccc2c(c1)CN(C(=S)Nc1ccccc1)CCS2 +NC1(c2ccc(-c3nc4ccc(-c5cnc[nH]5)cn4c3-c3ccccc3)cc2)CCC1 +COc1cc(CN(C)C(C)c2ccc3c(c2)CCO3)ccc1OCCN1C(=O)CN(C)C1=O +O=S(=O)(Nc1ccncn1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1Cl +COC(=O)C(C)(C)Cn1c(=O)[nH]c(=Nc2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCC2)c1=O +CC(C)C(=O)N1CCCC12CCN(c1ncnc3[nH]ccc13)C2 +CCN(Cc1cnc[nH]1)c1ccc(CCc2ccc(Cl)cc2)cc1 +O=C(Cn1nc2ccc(Cl)cc2n1)NCC1CCCN2CCCCC12 +N#CC1(n2cc(C(NC(=O)c3ccsc3)C3CCCC3)nn2)CC1 +Cc1ccccc1-c1noc(Cn2nc(CC(=O)O)c3ccccc3c2=O)n1 +O=S1(=O)NC2(CN1CC(F)(F)F)C1CCC2Cc2cc(-c3cn(-c4ccc(Cl)cc4)cn3)ccc2C1 +Cc1cc(Oc2ncccc2OC(F)(F)F)ccc1-c1c(C)n[nH]c(=O)c1C +CC1C=C(c2c[nH]c(-c3ccc(F)cc3)c2-c2ccncc2)CCN1 +O=c1[nH]c2ccc(Nc3nccc(Nc4ccccc4Cl)n3)cc2[nH]1 +C[n+]1c2ccccc2c(N)c2cc(Nc3nc(N)nc(Nc4ccc5c(c4)c(N)c4ccccc4[n+]5C)n3)ccc21 +CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(=O)O)c2ccccc2C)cc1 +Brc1cccc(Nc2ncnc3cc4[nH]ccc4cc23)c1 +FC(F)(F)c1ccc(Nc2noc3c(-c4ccc5[nH]ccc5c4)cccc23)cc1 +CCn1cc(C2(c3nnc(S)o3)NC(c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 +O=C1c2ccccc2C(=O)N1CCOCCN1CCN(c2nsc3ccccc23)CC1 +CCOCCOCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +c1ccc(CCCCN2CCN(Cc3cc4ccccc4o3)CC2)cc1 +COc1cc2c(cc1O)C1Cc3sc(CC(C)(C)C)cc3CN1CC2 +COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(F)F)cc1 +COc1ccc(S(=O)(=O)N2CCN(C(=O)Cn3c(=O)oc4ccc(Cl)cc43)C(CN3CCCC3)C2)cc1OC +COc1ccc2ccc(S(=O)(=O)NC3CCN(Cc4cc5c(N)nccc5s4)C3=O)cc2c1 +O=C(Nc1cccc(CCCCOCCCCCCNCC(O)c2ccc(O)c(CO)c2)c1)NC1CCCCC1 +CC(=O)c1ccc(OCCCN2CCC(NC(=O)C(C)NC(=O)OC(C)(C)C)C2)cc1 +Cn1cnc2cc(-c3ccc(C4(N)CC4)cc3)nc(NCCCO)c2c1=O +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CC1 +CCn1c(=O)n(CC)c2cc(-c3[nH]cnc3-c3ccccc3)ccc21 +CC(NC(=O)C(CCC(=O)O)NC(=O)Nc1ccc(C(=N)N)cc1)c1cccc(Br)c1 +CC(C)(C)NCc1ccc2c(c1)CCCC2NC(=O)CC1CCCCN1S(=O)(=O)c1cccc(Cl)c1 +CC1c2c[nH]nc2-c2cc(F)ccc2N1S(=O)(=O)c1cnn(C)c1 +O=C(Nc1nnc(-c2ccc3c(c2)CCCC3)o1)c1ccc(Cl)cc1Cl +CC(C)(C)NC(=O)c1ccccc1CC(O)C(CSc1ccc2ccccc2c1)NC(=O)c1cccc2c1CCNC2 +CN(Cc1ccccc1)CC1CCCC1c1c[nH]c2ccc(C#N)cc12 +O=C(NCc1cn[nH]n1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C1NCc2cc(Nc3ccc(F)cc3F)ccc2N1c1c(Cl)cccc1Cl +COC1CCC2(CC1)Cc1ccc(C#CC3CC3)cc1C21CC(=O)N(C)C(N)=N1 +O=S(=O)(NC1CCN(CCCO)CC1)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F +Cc1cc(C(=O)Nc2ccc(C3CCCNC3)cc2)ccc1Cl +CC(=O)c1sc(NC(=O)CCS(=O)(=O)c2ccccc2)nc1C +CC(C(=O)NCc1ccc(C2CC2)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 +COc1nc(Nc2cccc3c2nc(-c2ccc(F)cc2)n3C)ccc1-n1cnc(C)c1 +CCC1NC(=O)c2[nH]c3ccc(F)cc3c2-c2ccccc21 +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccccc3Cl)cc12 +COc1ccc2c(c1)C(NC(=O)CCCCN1CCN(c3ccccc3OC)CC1)CCC2 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1Nc1ccc(OCc3ccncc3)cc1CC2 +CC1Cn2c(nnc2-c2cnccn2)C(=O)N1Cc1c(Cl)cccc1Cl +OCC1OC(c2cccc(CCc3ccccc3)c2)C(O)C(O)C1O +Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3OC(C)CF)c12 +CC(C)(O)c1ccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)cc1 +COc1cc(Nc2cnc(C#N)c(OC(C)CN(C)C)n2)ncc1-c1cnn(C)c1 +OCC(O)CNc1cc(-c2ccc(Cl)cc2)nc2ccccc12 +COCCN(C)c1ncc2ncnc(Nc3cc(C(=O)Nc4ccc(OC)c(C(F)(F)F)c4)ccc3Cl)c2n1 +O=C(NO)C1CN(Cc2ccc(-c3ccc(F)cc3)cc2)C(=O)N1 +Cc1cccc(CCCCCCC(=O)c2ncc(-c3ccccn3)o2)c1 +Cc1cn2cc(CC(C)CN3CC4CCCCC4C(C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)C3)ccc2n1 +CNC(C)C(=O)Nc1ccc2c(n1)CN(c1cccc(Cl)c1)C(=O)N2c1cccc(Cl)c1 +CCCCCC(=O)NCc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F +CC(=O)N1CCC(c2cc(Nc3cc(C(F)(F)F)ccn3)nc(N3CCC(F)(F)C3)n2)CC1 +CC1(C)CC(=O)c2sc(N3CCOc4ccc(-c5ccncc5)cc43)nc2C1 +Cc1cc(C)cc(C(=O)c2cc(Cl)ccc2Oc2ccnc(Nc3ccc(C#N)cc3)n2)c1 +O=C(Nc1cc(Cl)ccc1OC1CCC(O)CC1)c1cnn2cc(O)cnc12 +O=C1C(=Cc2ccc(F)cc2)CCC1=Cc1ccc(F)cc1 +CCN(Cc1ccn(C)n1)C(=O)CN(c1cc(N(C)C)ccc1Cl)S(=O)(=O)c1ccc(OC)c(OC)c1 +COc1ccc2c(=O)c(Cn3ccnc3)c(-c3ccc([N+](=O)[O-])cc3)oc2c1 +COc1ccc(CNc2nc(N3CC4CC4C3)ncc2C(=O)NCc2ccccn2)cc1Cl +O=C(Nc1cnccn1)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CCN1CCN(c2nc3ccccc3c3c2CCc2ccccc2-3)CC1 +COc1ccc(C(=O)N2CCC(=CC(=O)NC3CCN(Cc4ccc5cc(F)ccc5c4)C3)CC2)cc1 +Cn1cccc1C=Cc1cc(C=Cc2ccc(OCc3ccccn3)cc2F)n[nH]1 +COc1ccccc1N1CCN(CCCNc2ccccc2C(=O)c2ccccc2)CC1 +Cc1ccc(NS(=O)(=O)c2ccc(-c3c(C)c(CC(=O)O)cc4ccc(Cl)cc34)cc2)cc1 +CN(c1cc(F)c(F)c(F)c1)c1cnc2nc(N)nc(N)c2c1 +OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 +N=C(N)c1cccc(-c2cccc(C(CCCNc3ccncc3)C(=O)O)c2)c1 +COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(CN3CCOCC3)n(C(C)COC(F)F)c12 +N=C(N)c1ccc(C2=NOC(CC(=O)NCC(NS(=O)(=O)c3ccccc3Br)C(=O)O)C2)cc1 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC2CCCC2)C(=O)CO)c1 +Cc1cnc(C(=O)NC(Cc2nc(I)n(Cc3ccccc3)c2I)C(=O)N2CCCC2C(N)=O)cn1 +C#CCc1cc(OCOCCOC)c(C23CC4CC(CC(C4)C2)C3)cc1C(=O)C=Cc1ccc(C(=O)O)cc1 +COc1ccc(CC(=O)NC(=N)NC(Cc2ccccc2)C(=O)NCCN2C(=O)c3ccccc3C2=O)cc1OC +Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1Nc1ccnc(OCC2CCCN(C)C2)n1 +N=C(NCCCC(N)CC(O)CCCN)N[N+](=O)[O-] +COc1cccc(S(=O)(=O)NCc2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)c1 +O=C(Nc1ncc(Br)s1)C1C(C(=O)NC2CCNCC2)C2CCC1C21CC1 +CCCN(CCN1CCN(C(=O)c2c[nH]c3ccccc23)CC1)C1CCc2c(O)cccc2C1 +O=C(c1cncc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1)N1CCCCCCCC1 +Cc1[nH]c(C(=O)NC2CCN(c3ncc(C(=O)O)s3)CC2N=[N+]=[N-])c(Cl)c1Cl +Clc1ccccc1CSc1nnc(-c2ccc3c(c2)OCCO3)n1-c1ccccc1 +CC1(C)OC2C3CC(C2O1)N(c1cc(Cc2n[nH]c(=O)c4c2CCCC4)ccc1F)C3=O +CCCn1nc(-c2ccnc(Nc3cccc(S(N)(=O)=O)c3)n2)c2ccccc21 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4COCc4ccc(C(O)CO)cc4)C(C2)N(CC2CC2)CCC315 +COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 +COC1CCC2(CC1)Cc1ccc(NC(=O)c3ccc(Cl)cn3)cc1C21N=C(C)C(N)=N1 +O=C(NC1CCN(CC2CCCCCC2)CC1)C(O)(c1ccccc1)C1CCC(F)(F)C1 +CC(C)(C)OC(=O)NC1CCN(C(=O)OC2C3CC4CC2CC(C(C)(C)O)(C4)C3)C1 +O=C(Nc1ccncn1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +CC(=O)N1CCC(n2cc(-c3cnc(N)c(-c4nc5ccc(Cl)cc5o4)c3)cn2)CC1 +NC(=O)c1cccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)c1 +CCc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 +CCOc1cc2c3cc(OC)c(OC)cc3c[n+](C)c2c2cc(OC)c(O)cc12 +CCCCc1nn(CCC2CCCCC2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cccc(-c2cc(N)c(C(=O)c3cc(OC)c(OC)c(OC)c3)s2)c1 +COC(=O)C1OC(n2cc(-c3ccc(S(N)(=O)=O)cc3)nn2)C(O)C(O)C1O +O=C(O)CN1CCCCCCC(NC(CCc2ccccc2)C(=O)O)C1=O +COC(CCc1ccccc1)c1ccccc1OCC(O)CN1CCN(Cc2ccccc2)CC1 +O=C(c1ccccc1)c1ccc2c(c1)oc(=O)n2C(=O)NCCCCc1ccccc1 +N#Cc1ccc(-c2cc3c(o2)C(=O)N(Cc2ccccc2-c2cncnc2)c2ccc(C4CCNCC4)cc2C3(F)F)cc1 +Cn1cc(C2NC(c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 +O=C(c1cc(N=C=S)cc2ccccc12)c1cn(CCN2CCOCC2)c2ccccc12 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C3=NCC(C)(C)O3)cc2n1Cc1ccccc1 +CC(C)Oc1ccc(Nc2ncc(NCCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F +O=C(O)CCCCN1C(=O)C(c2ccc(Cl)cc2)N(C(C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21 +COc1ccc(-c2ncc3c(n2)-c2[nH]c4c(c2CC3)C(=O)NCC4)cc1 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5[nH]c(C(N)=O)cc5c4)CC3)c2c1 +COc1cc(-c2cn(-c3nccc(N4CCOCC4)n3)cn2)cc(OC)c1O +Cc1cnc(Nc2cc(Cc3ccccc3)nc(NC3CCC(O)CC3)n2)s1 +COc1ccccc1C(=O)NC(=O)Nc1ccc(-c2ccccc2)c(C(C)C)c1 +Cc1ccc(C(=O)Nc2cccc(N(C)C)c2)cc1Nc1ncnc2cnc(N3CCN(C)CC3)nc12 +Cc1cc(S(=O)(=O)NC(=N)Nc2ccc(S(N)(=O)=O)cc2)c(SCc2cccc3ccccc23)cc1Cl +COC(=O)C1=C(c2ccc(CNc3nccc(C)c3NC(=O)CC#N)cc2)CCC1 +O=C(CCCOc1ccccc1)NCC(=O)N(O)CCCP(=O)(O)O +CN1CCN(c2nc(NCc3ccccc3)c3cc(Cl)ccc3n2)CC1 +CC12CN(C(=O)c3ccccc3)CC(C)(O1)C1C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C12 +O=C(O)CN(CC1CC(F)CN1)C(=O)c1ccc(-c2cnc3ccc(NCC4CC4)nn23)cc1 +Oc1cccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)c1 +O=C(CCCCCCC(=O)c1ccc(C(F)(F)F)cc1)NO +COc1ccc(F)cc1-c1ccc2c(c1)C(C(C)OCCc1ccccc1)=CC(C)(C)N2 +Cc1cc(=O)oc2c1ccc1oc(C(=O)c3ccccc3)c(-c3ccccc3)c12 +CC(C)c1nc2c(c(Nc3ccc(C(C)(C)C)cc3)n1)CCN(c1ncccc1C(F)(F)F)C2 +Cc1ncc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(C(F)(F)F)cc1NC(=S)C2 +Nc1nc(Cl)c(-c2cc3ccccc3o2)c(NC2CC(CO)C(O)C2O)n1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCN(CC(=O)NC3CCOCC3)C2)cn1 +NS(=O)(=O)c1ccc2[nH]c(-c3ccc(C(=O)c4ccc(Cl)cc4)cc3)nc2c1 +CC(C(=O)NC1CCC1)c1ccc(OC2CCN(c3ncnc(OCC(C)(F)F)c3F)C2)cc1 +Nc1ncnc2c1nc(Br)n2C1OC2COP(=O)(O)OC2C1O +CC(C)N1C(=O)C(NC(=O)C(Cc2cccc(F)c2)NC(=O)OC(C)(C)C)CCc2ccccc21 +CCC(=C(c1ccccc1)c1ccc(C=CC(=O)N(C2CCCCC2)C2CCCCC2)cc1)c1ccccc1 +CONc1nc(C#Cc2ccc(F)cc2)nc2c1ncn2C1OC(CO)C(O)C1O +CCN(CC)CC(C(C)C)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +O=C(NC1CC1c1ccccc1)N1CCC(Oc2ccncc2)CC1 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+O=C(OCCCc1cccnc1)C1CCCN1C(=S)NC1CCCCC1 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4COC(=O)C(N)CC(C)C)C(C2)N(CC2CC2)CCC315 +O=c1c2cn[nH]c2c2ccc(-c3cccnc3N3CCCC3)cc2n1CC(F)(F)F +CC(=O)NCCNC(C)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 +CC(C)N1CCN(C(CN2CCN(CCCc3ccccc3-c3ccc(OC(F)(F)F)cc3)CC2)c2ccc(F)cc2)CC1 +CN(CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21)CCc1ccccc1 +COc1ccccc1N1CCN(CCCC(=O)NC2CCCc3cccc(OC)c32)CC1 +C=CC(=O)Nc1cc(Nc2ncc(Cl)c(-c3cnn4ccccc34)n2)c(OC)cc1N1CCN(C)CC1 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(N2CCC(C(=O)O)CC2)cc1Cl +CCOC(=O)C1=C(c2ccccc2)NC(C)=C(C#N)C1c1ccccc1Cl +CCCCCCC(O)CCCC(O)C1CCC(C(O)CCC(O)C(O)CCCCCCCCCCCCC2=CC(C)OC2=O)O1 +CCOC(=O)c1sc(Nc2nc(NC)c3ncn(Cc4ccc(S(C)(=O)=O)cc4)c3n2)nc1C +CC1CCC(Oc2nc(N)c(C(N)=O)c(OC3CCCC3O)n2)CC1 +O=C(O)CCC(=O)N1CCc2cc(-c3noc(-c4ccc(OC(F)(F)F)cc4)n3)ccc21 +NS(=O)(=O)c1ccc(SCc2cccc(-c3ccccc3)c2)s1 +CC1(C)C2CC3OB(C(CCCCN)NC(=O)Cn4nc(CO)nc4Cc4ccccc4)OC3(C)C1C2 +CCNc1nnc(CSc2nc3sc4c(c3c(=O)n2CC)CCCC4)s1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)cc1)c1nnn(-c2ccc(F)c(F)c2)c1C(F)(F)F +COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)CC(C)O)c1Cl +COC(=O)C(CNC(=O)c1ccc(-c2ccccc2)cc1)Cc1cccc(C(=N)N)c1 +CCCCOc1ccc(OCCCC)c(C(=O)C=Cc2ccc(Cl)cc2)c1 +OC1(c2ccc(OCc3ccccc3)cc2)c2ccccc2C2=NCCCN21 +Cc1c(-c2ccc(Cc3ccc(OC(F)(F)F)cc3)cc2)[nH]c2ncccc2c1=O +Cn1cc(Nc2ncc(Cl)c(NC3CCCC3C(N)=O)n2)cn1 +COc1ccc(C2=NN(CCCCCNCC(O)c3ccc(O)c(CO)c3)C(=O)C3CCCCC23)cc1OC +COc1cc2c(cc1OC)C(=O)C(=Cc1cccc(CN(C)C)c1)C2 +O=C1Nc2cccc(C3CCNCC3)c2C1=Cc1[nH]cc2c1CCNC2=O +Cc1c(C(O)CN2CCN(CC(O)c3ccc4c(c3C)COC4=O)CC2)ccc2c1COC2=O +COc1ccc(Nc2cc(Oc3c(C)cc(C)cc3C)n3ncnc3n2)cc1 +CCC(=O)c1cccc2c(C)c(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)sc12 +O=C(NCc1ccncc1)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +O=C1N(Cc2cc(F)cc3c2OCOC3)CCCC12CCN(c1cnc3ccccc3n1)CC2 +COc1ccccc1N1CCN(c2ccncc2S(N)(=O)=O)CC1 +Cc1cnc(C)c(CCC2CCN(S(=O)(=O)CC3(N(O)C=O)CCOCC3)CC2)c1 +COC1COCCC1NC1CC2OCCC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +CC1CCc2nn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)cc21 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+NCc1ccccc1C1(O)CCN(C(c2ccccc2F)c2ccccc2F)CC1 +COc1ccc(Cl)cc1-c1cc(Nc2ccc(Br)cc2)nc(N)n1 +Nc1ncc(-c2cccc(C(F)(F)F)c2)nc1C(=O)NC1CCCC1 +Cc1nc(C)c(-c2ccnc(Nc3cccc(N)c3)n2)s1 +CC(C)(C)NCc1ccc2c(c1)CCCC2NC(=O)CC1CCCCN1S(=O)(=O)c1cccc2nsnc12 +O=C(CCN1CCCCC1)Nc1ccc(NC(=O)Nc2ccc(N(CCCl)CCCl)cc2)cc1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(CO)c1cc2cc(F)ccc2[nH]1 +CCCC(Nc1nc(N)nc(N)c1C#N)c1nc2ccc(F)c(Cl)c2c(=O)n1-c1ccc(N)nc1 +Brc1cccc(Nc2ncnc3cc4c(cc23)OCCCO4)c1 +CN(C)CCCNC(=O)c1cccc(NC(=O)Nc2ccc(N(CCCl)CCCl)cc2)c1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCN(CCS(C)(=O)=O)CC4)nc12 +CCOCC(Cc1ccc(F)cc1)Nc1nc2cc(C(C)C)ccc2o1 +CC#CCn1ccc(C(=O)Nc2csc(C34COC(C)CC3CSC(N)=N4)n2)n1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2ccoc2)cc1 +CC(CC(=O)O)N1CCC(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +COc1cc(CNC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)ccn1 +Cc1cc(OC2CCN(c3nc(Nc4cc(C(C)(C)C)ccc4C)c4c(ncn4C)n3)CC2)ncn1 +CC(C)CC(=O)NCc1cccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)c1 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+C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OCCOC +CC(c1ccc(-c2cccc(=O)n2C)cc1)N1CCC(CCCO)(c2ccccc2)OC1=O +CC(=O)N1CCN(C(=O)C2CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC2)CC1 +C=C1C(=O)C23CCC4C5(C)CCCC4(OC5=O)C2(C)CCC1(OC)C3 +COc1ccc(C2=NN(C(=O)c3cncc(Br)c3)C(c3ccc(Cl)cc3)C2)cc1 +O=C(NCC1CCOCC1)C1CCN(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +c1cc2[nH]cc(CCN3CCC3)c2cc1-n1cnnc1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(Cl)c2)C1 +O=C(Cc1cccc2cnccc12)Nc1scnc1-c1nc[nH]n1 +CCC(=O)NC(c1cccs1)c1cc(Cl)c2cccnc2c1O +Fc1ccc(-c2nc(F)ccc2-c2ccc(OCc3ccc4ccccc4n3)cc2)cc1 +N#CC1CSCN1C(=O)CN(N)C1CCN(CC(=O)Nc2ccc(S(N)(=O)=O)cc2)CC1 +CCCn1c(=O)c2nc(C=Cc3cc(F)cc(F)c3)[nH]c2n(CCC)c1=O +CC1(C)COP(=O)(Nc2ccc(-c3cc4ccc(OS(N)(=O)=O)cc4oc3=O)cc2)OC1 +CCCn1c(=O)c2nc(-c3ccc(OCc4noc(-c5ccc(C)cc5)n4)cc3)[nH]c2n(CCC)c1=O +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCNC(C)(CO)CO +CC(C)CCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1C(=O)O +COc1ccc(CN(C)S(=O)(=O)c2cccc(Oc3cccc(-c4c(C(C)C)nc5c(Cl)cccn45)c3)c2)cc1 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+COCCOCCOCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +Fc1ccc2c(c1)nc(-c1ccccn1)n2-c1ccc(OCCCN2CCCCC2)cc1 +Cc1c(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)cccc1-c1nc2ccccc2s1 +CN1C(=O)C(c2ccncc2)(c2cccc(-c3cccc(F)c3)c2)N=C1N +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1cc2cc(-c3cnn(CC(C)(C)O)c3)ccc2cn1 +CC1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(CO)C5CCC43C)C2C1 +O=C(CCC1CCCN(Cc2ccc3c(c2)OCCO3)C1)NCc1ccc(F)c(F)c1 +O=C(NCC12CCC3(O1)C1Cc4ccc(O)cc4C3(CCN1Cc1ccccc1)C2)c1ccccc1 +CC(NC(=O)C(C#N)=Cc1ccc(O)c(O)c1)c1ccccc1 +CC(NC(C)(C)C)C(=O)c1cccc([N+](=O)[O-])c1 +CC(c1ccccc1)N1CCCC(CNCc2cc(C(=O)O)ccn2)C1=O +CCCCN(CCO)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 +CCOC(=O)c1cnccc1Nc1nc(-c2nn(Cc3ccccc3F)c3c2CCC3)ncc1Oc1ccccc1C(=O)OCC +Cc1nc(N)ncc1-c1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1F +COc1cccc(-c2cc3c(C)nc(N)nc3n(C3CCCC3)c2=O)c1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4cccc(S(C)(=O)=O)c4)cc23)c1F +N=C(N)c1ccc(-c2ccc(C3=CCC(O)(CC(=O)O)CC3)cn2)cc1 +N=C(N)NCCCC1NC(CNC(=O)C=Cc2c(F)cccc2Cl)CCN(CC(c2ccccc2)c2ccccc2)C1=O +O=[N+]([O-])c1cn2c(n1)OCC(OCc1ccc(-c3ccc(C(F)(F)F)cc3)cn1)C2 +Nc1cccc(-c2cc(COCC3(c4ccccc4)CCNCC3)cc(C(F)(F)F)c2)c1 +Cc1ccc(C2COC(=O)N2c2ccn3ncc(-c4ccc(-c5nc[nH]n5)c(F)c4)c3n2)cn1 +CC1CCc2cc(-c3ncccc3C#N)ccc2N1C(=O)c1ccc(O)cc1O +OC1(CCCc2ccc(-c3nnn[nH]3)cc2)CCN(CC2CN(CC3CCCCC3)CC2c2ccccc2)CC1 +O=C(CCN1CCN2c3ccccc3CCC2C1)c1ccc(F)cc1 +O=S(=O)(Nc1ccc(NS(=O)(=O)c2cccc(F)c2)cc1)c1cccc(F)c1 +CC(C)(O)C#Cc1cc2c(cc1F)C1CC(C1)c1c-2nc(C(N)=O)n1C(F)F +CC1(C)OC(=O)N(C2CCC(NC(=O)c3ccc[nH]3)CC2)C1c1ccccc1 +CN(C)Cc1ccc2nc(NC(=O)NN=Cc3cn(Cc4ccccc4)c4ccccc34)sc2c1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(N1C(=O)C=CC1=O)C2 +CC(=O)OCCn1c(Sc2nc3cccc(Cl)c3s2)nc2c(N)ncnc21 +CNCc1csc(NC(=O)c2cc(C(C)(C)C)nn2Cc2ccccc2)n1 +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1c(Oc2ccccc2)cccc1N1CCCCCC1 +CN1C(=O)OC(C)(C)c2cc(Nc3cccc(Cl)c3Cl)ccc21 +CCCCc1cc(OC2CCN(CCNS(=O)(=O)CC)CC2)c2ncccc2c1 +Nc1ccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2sc3ccccc3c2Br)cc1 +CC(C)(O)c1cnn2c(-c3ccc(F)c(-c4ccc(F)cn4)c3)cnc2n1 +Cc1cccc(N2CCN(CCCCNc3nc(NCc4ccco4)c4ccccc4n3)CC2)c1C +O=c1cc(C(F)(F)F)c2cc(NC3CCCC3)ccc2[nH]1 +CC(C)CC(C)(N)COc1ncc(-c2ccnc3ccccc23)cc1C(F)F +Cc1nn(Cc2c(Cl)cccc2C2CC2)c2cc(-c3nnn[nH]3)cnc12 +O=C(NO)c1cnc(Nc2nnc(-c3ccc(O)cc3)o2)nc1 +CN1CCCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +CN1C(=O)CCN(C2CCCC2)c2nc(Nc3ccc(N4CCC(O)CC4)cn3)ncc21 +Cc1cc(C(N)=O)ccc1-c1c(CCC(=O)O)ccn1-c1ccc(-n2ccnc2)cc1 +O=C(c1cccc(Cl)c1Cl)N1CCc2c(ncnc2-c2ccn[nH]2)C1 +COC1OC(C(O)C(C)(C)O)CC1C1CCC2(C)C3=CCC4C(C)(C)C(=O)CCC4(C)C3CCC12C +COc1ccc(C2CC2COc2cc(N(Cc3ccc(C)nc3C)Cc3ccc(C)nc3C)c(=O)n(C)n2)nc1 +O=C(c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1ccc(CN2CCOCC2)cc1)C1CC1 +Cc1cccc(S(=O)(=O)Nc2ccc(C=CC(=O)NO)cc2)c1 +CCN(CC)CCCS(=O)(=O)NC(CCc1ccccc1)c1nc(-c2ccc(OC)cc2)n[nH]1 +COc1ccc2c(c1)c(C=C1Oc3cc(O)cc(O)c3C1=O)c(C)n2CCCN1CCOCC1 +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(NC4CCN(c5ccc(C(=O)NO)cc5)CC4)ccc3OCC)nc12 +O=C(CNC(=O)c1ccccn1)NC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5 +CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1[N+](=O)[O-] 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+Cc1ccc(CN2CCNCC2)cc1NC(=O)c1ccc(Nc2nc(-c3ccc(OC(F)(F)F)cc3)c3cccn3n2)cc1 +O=C(NC(Cc1ccc(OCCc2cccc(NC3CCCC3)n2)cc1)C(=O)O)c1c(Cl)cccc1Cl +COc1cc2c(cc1OC)C(=O)C(Oc1ccc(C(C)N3CCCC3)cc1)C2 +CCc1nc(NC(=O)NS(=O)(=O)c2cc(C)c(CCO)s2)sc1OC +CCCC(CC(O)N1CCCC(Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(-c2nnnn2C)c1 +N#Cc1ccc(Cn2nc3c(-c4ccncc4)c(-c4ccc(Cl)cc4)c(=O)n(Cc4ccc(C#N)cc4)n3c2=O)cc1 +COc1ccc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(OC)c(N2CCNCC2)c1 +NC(CCC(=O)Nc1cc(Cl)cc(S(=O)(=O)O)c1O)c1nnc(Cc2ccccc2)o1 +COc1cc(C(=O)C=Cc2cccc3[nH]ccc23)cc(OC)c1OC +CC(=O)N1CCN(c2cc(-c3cc(Cl)c4c(N)ncnn34)ccc2C(F)(F)F)C(=O)C1(C)C +CNC(=O)CCCCCC(NC(=O)c1cncs1)c1ncc(-c2ccc3[nH]ncc3c2)[nH]1 +CN1CCN(C(=O)C(CNC(=O)c2ccc(Cl)s2)NS(=O)(=O)c2cccc(N3CCCC3=O)c2Cl)CC1 +CCOc1cccnc1C(=O)NC1CCCC1(C)Nc1cnc(C(F)(F)F)cn1 +CC(=O)c1cccc(-c2cccc(-n3cc(C(=O)Nc4nccc(Cl)c4Cl)c(=O)c4cccnc43)c2)c1 +CC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2c(F)cccc2C(N)CC(C)C)CC1 +CS(=O)(=O)Nc1ccc(Nc2c3ccc(Cl)cc3nc3cc(Cl)ccc23)cc1 +Cc1ccc2c(C3CCN(CCN4CCN(C(C)C)C4=O)CC3)cn(-c3ccc(Cl)cc3)c2c1 +CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4cn[nH]c4)cc3)n2)c(=O)c1=O +CC(C)Nc1ncc2c(n1)CN(C(=O)NC1(c3ccc(Cl)c(Cl)c3)CCNCC1)CC2 +COc1ccc(CN2C(=O)c3ccccc3C2=O)cc1C(=O)Nc1ccccc1N1CCOCC1 +CN(Cc1ccccc1)Cc1ccc(C=C2CCc3cc(OCCCCCN4CCCCC4)ccc3C2=O)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(Cl)c(Cl)c2)CC1 +O=C(C=Cc1ccc(O)c(O)c1)OCC(OC(=O)C=Cc1ccc(O)c(O)c1)C(=O)O +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1CCCCC(=O)NO +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(OC(F)F)c1 +Cc1ccccc1S(=O)(=O)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 +O=C(NCCCO)C(Cc1ccc(Cl)cc1)NC(=O)C1(c2ccc(Cl)cc2)CC1 +N#Cc1ccc(N(CC2CCc3cc(OS(N)(=O)=O)ccc3C2)n2cnnc2)cc1 +COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(C(F)(F)c3ccccn3)n(CC3CCOCC3)c12 +CC(C)CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)N1CCOCC1)B(O)O +CN(C)CCCNC(=O)c1cccc(-c2cc(Cl)c3c(c2)C2(CCCCC2)NC(=O)N3)c1 +O=C(O)COc1cccc(Oc2ccc3c(c2)CC(NCC(O)c2cccc(Cl)c2)CC3)c1 +NS(=O)(=O)c1ccc(N2C(=O)c3c(Br)c(Br)c(Br)c(Br)c3C2=O)cc1 +Cc1csc(-c2nc(CN3CCCC3=O)[nH]c2-c2ccc3ncsc3c2)n1 +FC(F)(F)c1ccccc1CNC1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 +CCCCn1c(=O)c2nc(-c3ccc(OCC(=O)O)cc3)[nH]c2n(CCCC)c1=O +CC1(C)OCC(=O)Nc2ccc(-c3ccc(F)cc3)cc21 +CN1CCN(Cc2cccc3c2c(Br)cn3S(=O)(=O)c2ccc(F)cc2)CC1 +CCC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 +CCc1cc(NC(=O)NC(C)C(O)CN(CC)C(C)CCc2ccc(F)cc2)cc(-c2nnnn2C)c1 +COc1ccc(C(C)(CC(=O)O)NC(=O)C2CCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)cc1 +[H]c1cccc([H])c1-c1nnc(CC2CCCN2C(=O)c2nc(C)sc2-c2ccccc2F)o1 +C=C(C(=O)OCC)C(OCCC(=O)OCC)c1ccc(Cl)cc1Cl +CCCCc1nc2ccn(Cc3cccc(Cl)c3)c(=O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCc1c(C)[nH]c(=O)c(-c2ccco2)c1Oc1cc(C)cc(C)c1 +CN(CCc1ccccc1)C(=O)Cc1cc(C=CC(=O)O)cc2c(OCc3ccccc3)cccc12 +COc1ccc(NCCNC(=O)C2(Nc3cccc(-c4ccccc4)c3)CCCCC2)cc1 +O=C(CCCc1c[nH]nn1)NC1CCCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1 +Cc1cc(S(=O)(=O)NC(CC2CC2)C(=O)NO)ccc1F +COc1ccccc1NC1=C(N2CCCCC2)C(=O)c2ccccc2C1=O +CC(C)c1nc(C(c2ccccc2)c2ccccc2)cc(-c2ccc(F)cc2)c1C#CP(=O)(O)CC(O)CC(=O)O +CC(C)C(NC(=O)Cn1c(-c2ccc(N)cc2)ncc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F +CCOCCOc1ccc(S(=O)(=O)N2CC(O)C(O)C(O)C2C(=O)NO)cc1 +CCc1ccc2c(c1)nc(Cn1c(=O)n(C(C)C)c3ccccc31)n2CCC(C)C +CCc1ccc(NC(=O)Nc2ccc(S(=O)(=O)Nc3ccc(CC(C)(C)N)cc3)cc2)cc1 +CC(C)CC(NC(=O)Nc1ccc(C(F)(F)F)cc1)C(=O)NC(C)(C)C(=O)O +Cc1ccc(-n2nc(C3CCN(C4CCC5CC54)CC3)cc2NC(=O)c2cnn3cccnc23)cc1 +[N-]=[N+]=NCc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F +O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(C(F)(F)F)ccc1O +Cc1n[nH]c(C(=O)O)c1Cc1cccc(-c2cccc(F)c2)c1 +CC(C)(C)c1cc(C=NNC(=O)c2ccccc2)c(O)c(C(C)(C)C)c1 +CC(C)N1CC(N=CC(C=N)c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)C1 +CC(C)(C)Cn1c2ccccc2c2cc(NC(=O)N3CCOCC3)ccc21 +CC1(C)CNc2cc3nc(O)cc(C(F)(F)F)c3cc21 +c1ccc(-c2[nH]c3ccccc3c2C2CCCNC2)cc1 +Cc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1 +CC(C)n1c(CCC(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)c1C(=O)Nc1ccccc1 +CC12CC3CC(C)(CC(C1)C3NC1CCN(Cc3ccc(Cl)cc3F)CC1)C2 +CCN1CCN(C(N=O)c2ccc(C#CC3(CN4Cc5ccc(OC)cc5C4=O)NC(=O)NC3=O)cc2)CC1 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+O=C(CCNc1ccccc1)Nc1ccc2nc3c4[nH]c5ccccc5c4ccn3c(=O)c2c1 +O=C(C1CCCN1)N1CCc2c(nc(O)c3ccccc23)C1 +CC(=O)Nc1cccc2c1C(=O)c1c(-c3sccc3C)n[nH]c1-2 +CCCCCC(C)N(Cc1ccc(OCC(C)C)cc1)C(Nc1ccc(OC)cc1OC)=C1C(=O)OC(C)(C)OC1=O +Nc1ncc(-c2ccc(C3(c4noc(-c5ccnnc5)n4)CCC3)cn2)cn1 +CNCC(O)C(c1cccc(F)c1)n1ccc2cccc(Cl)c21 +CCCC(NC1(C(=O)NC(Cc2nc(-c3ccccc3)co2)C(=O)O)CCCC1)C(=O)O +COc1cc2nc(-c3cccnc3)cc(O)c2cc1-c1cnco1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-n2nccn2)c1 +Cc1nc(N(C)c2ccc(OC(C)C)cc2)c2ccccc2n1 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)c(F)c1 +CCCC(NC(=O)C(C#N)=Cc1cccc(Br)n1)c1ccccc1 +Cc1ccc(C(Br)c2ccnc(Nc3ccc(C#N)cc3)n2)cc1 +Cc1cc(C)c(S(=O)(=O)NC(C)Cc2c[nH]c3cc(F)ccc23)c(C)c1 +COc1cc(C(=O)c2oc3cccc(O)c3c2C)cc(OC)c1OC +Nc1ccc(S(=O)(=O)Nc2nc(-c3cc(C(F)(F)F)ccc3F)cs2)cc1 +COc1cccc(Sc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)noc2CCCC=NO)c1 +Cc1ncc(C)n2nc(CCc3cn(C)c(-c4cscn4)n3)nc12 +O=C(O)c1ccc(COc2cccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)cc1 +CCCCCNC(=O)c1coc(C2C3CCC(O3)C2Cc2ccccc2CCC(=O)O)n1 +CC(C)(N)CNc1cc(-c2ccc[nH]2)c2c3c(ccc(F)c13)NC2=O +CCCN1CCC=C(c2c[nH]c3ccc(OC)cc23)C1 +C=CCNc1nccc(-c2[nH]c(C3OCC(C)(C(=O)N4CCOCC4)CO3)nc2-c2ccc(F)cc2)n1 +O=C(CCCCCCC(=O)NNC=Cc1cc(O)ccc1O)NO +Cc1cc(S(=O)(=O)NCc2cccnc2)cnc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CCc4ccccc43)c2)[nH]1 +c1cc2c3cnc(Nc4ccc(NCC5COCCN5)nn4)nc3n(C3CCCC3)c2cn1 +COCCc1nc2c(c(C(F)(F)F)n1)CCN(C(=O)CC(N)CN1C(=O)CCC(F)(F)C1O)C2 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CCN)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1cccc(C(N)=O)c1)C(=O)O +CC(C)c1nn(-c2ccccc2)c(-c2ccc(F)cc2)c1CCC(O)CC(O)CC(=O)O +NC(=S)Nc1cccc(OCCCCCOc2ccc(N3CCCCC3)cc2)c1 +Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3OC3CCN(Cc4ncon4)CC3)c12 +O=c1ccc(OCCCN2CCCCC2)nn1-c1ccc(Cl)cc1Cl +Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3c(C)c[nH]c3n2)c(OC(C)C)cc1C1CCNCC1 +O=C(C=Cc1ccc(O)cc1)c1ccc(OC2OC(CO)C(O)C(O)C2OC2OCC(O)(CO)C2O)cc1O +O=C(Cc1ccccc1F)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3F)s2)s1 +NC(CC(=O)N1CCc2n[nH]c(C(F)(F)F)c2C1)Cc1cc(F)ccc1F +CC(=O)CCCC(=O)NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCCc2ccccc2)C1=O +Cc1c(Cl)ccc2c1NC(=O)C2(c1ccc(O)cc1)c1ccc(O)cc1 +COC(C)CNC(=O)c1nc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)C(OC)C2)sc1C(=O)O +COC(=O)c1c(Cc2ccc(C(=O)NC3CCC(O)CC3)cc2)c(=O)c2ccc(C)nc2n1-c1ccccc1 +CC(=O)NCCNc1cccc(Nc2nc3ccc(C(=O)Nc4c(C)cccc4Cl)cc3s2)n1 +N#CC(Cc1ccc(-c2ccc3c(c2)CC(=O)N3)cc1F)NC(=O)C1NC2CC1C1CC21 +COc1cc(C(N)=O)c2ncnc(NC(CN(C)C)c3ccccc3OC)c2c1 +Nc1cnc(-c2ccc(C3CCC3)c(OCC(O)Cn3cnccc3=O)c2F)cn1 +Cc1ccc(C(=O)Nc2cccc(N3CCOCC3)c2)cc1-c1ccc2[nH]c(=O)ccc2c1 +COc1ccc(OC)c(Sc2ccc3nnc(-c4ccccn4)n3n2)c1 +N#Cc1ccnc(-c2ncc(C(=O)N3CCN(C(=O)c4ccc(Br)cc4)C(c4ccc(Cl)cc4)C3)o2)c1 +N=C(N)c1cccc(N(CCCc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CCOc2ccccc2)c1 +Cn1cncc1C(OCc1ccc(C#N)nc1-c1ccc2ccccc2c1)c1ccc(C#N)cc1 +Cc1cccc(-n2nc(C(N)=O)c3ccc4[nH]ncc4c32)c1 +COc1cc(C(=O)c2c(-n3ccnc3)[nH]c3ccccc23)cc(OC)c1OC +Cc1noc(CNC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)n1 +C=CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC=C)C1C=Cc1ccccc1OC +COc1cccc(-c2cc(NC(=O)NNc3ccc(N(CCCl)CCCl)cc3)c3cc4c(cc3n2)OCO4)c1 +COc1ccc2c(c1O)C13C=C(C#N)CCC1(O)C(C2)N(C)CC3 +COc1ccc(C(=N)NC(C)C)cc1-n1cc(-c2cccc(C(=N)NC(C)C)c2)nn1 +O=C(Cc1ccc(O)c(F)c1)NN=C1C(=O)Nc2c(Cl)ccc(Cl)c21 +CN1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(Cl)c3Cl)c2O)CC1 +CN1C2CCC1C(c1cc(-c3ccc(F)cc3)no1)C(c1ccc(Cl)cc1)C2 +NS(=O)(=O)c1ccc(-n2cc3c(n2)-c2ccc(Cl)cc2SC3)cc1 +Cc1cccc(-n2nnc3c2CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)C3C)n1 +CCNC(=O)Nc1cc2ccc(-c3cc(F)ccc3C)cc2cn1 +Cc1cccc(OC(c2ccc(Cl)c(Cl)c2)C2CNC2)c1 +COCCN1CC(=O)C(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)CC1=O +CCCN(CCOC)c1nc(C)nc2c1c(C)nn2-c1ccc(C(N)=O)nc1C +Fc1cc(F)c(CN2CCN(c3nc4cnccc4nc3NC3CC3)CC2)cc1F +CN1CCCC1Cc1c[nH]c2ccc(C3=CCN(C(S)=NC4CCCCC4)CC3)cc12 +CCC(C)(C)Cc1c[nH]c(CCc2ccc(-n3cncn3)cc2)n1 +O=C(O)CC1CCN(C(CC2CCC2)c2ccc(C(F)(F)F)nc2)C(c2ccc(C(F)(F)F)cc2)C1 +O=C(Nc1nc(-c2ccc(F)cc2)cs1)c1ccc([N+](=O)[O-])s1 +COc1ccc(-c2ccc(C(=O)O)cc2)cc1OC1CCCC1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCC3=CC(=O)CCC3(Cc3ccc(F)cc3)C2)cc1 +CCNc1nc2cc3c(cc2s1)CC1C2CCCCC32CCN1CC1CCC1 +CCN(CC#N)C(=O)C1CC(C(=O)N2CCOCC2)C(C)N1 +COc1cc(OC)cc(-c2cc3nc(C)ccc3cn2)c1 +Cc1nc(S(C)(=O)=O)ccc1Oc1ncnc(OC2CCN(C(=O)SC3CC3)CC2)c1F +O=C(NC(c1ccc(Cl)cc1)c1cc(Cl)c2cccnc2c1O)c1cccnc1 +CNC(C)(C)CC=CC(=O)N(C)C(Cc1ccc2ccccc2c1)C(=O)N(C)Cc1ccccc1 +O=C(Nc1c(Cl)cccc1Cl)C1c2ccccc2COc2ccc(Br)cc21 +Cc1cc(N2C(=O)c3nn(C4CN(C)C4)c(C)c3C2c2ccc(Cl)cc2)cn(C)c1=O +COc1cc2c(cc1O)C1CC(O)(c3ccc(OC(F)(F)F)cc3)CCN1CC2 +O=S(=O)(c1ccc(F)c(F)c1)N1CCCC(Cn2ccnc2)C1 +CCCCCc1ccccc1-c1ccc(OC(Cc2ccccc2)C(=O)O)cc1 +Cc1cc(C(=O)Nc2ccc(C(=O)N(C)C)cc2)n(-c2ccc3cc(Cl)ccc3c2)n1 +CCCCCCCCCCCCc1noc(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccccc2)n1 +NS(=O)(=O)c1ccc(COC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCC1CCCCC1 +N#CCc1c(C(=O)NCc2ccc(Cl)cc2Cl)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +N#Cc1c(N=Cc2ccc3ccccc3c2)c(C(=O)Nc2ccc(Cl)cc2)n2c1CCC2 +O=CNC1CCC(CCN2CCC(c3cccc4c3CCO4)CC2)CC1 +NC(=O)C1=CC(C2CCCCC2)CC(OCc2ccc(CO)cc2)O1 +CCC(NC(=O)c1c(N=[N+]=[N-])c(-c2ccccc2)nc2ccccc12)c1ccccc1 +COc1ccc(N(C)c2nc(C)nc3[nH]ccc23)cc1 +CCCCCC(C)(C)NCC(O)C(Cc1ccccc1)NC(=O)c1cc(NCC)cc(N2CCCC2=O)c1 +CCn1c(=O)c(C(=O)NCc2ccc(F)cc2)c(O)c2ncsc21 +CC1CNCC(C)N1C(=O)c1cn2c3c(cccc13)OCC2C1CCCCC1 +CC(C)COc1ccc(Sc2nc(N)nc3c2ncn3CCOCP(=O)(OCC(F)(F)F)OCC(F)(F)F)cc1 +COc1ccc([N+](=O)[O-])cc1OCC1CN(Cc2ccc(Cl)cc2)CCCO1 +COc1ccc(OC)c2c1c(OC)cc1c(=O)c(OCCOCCOCCOCCOC(=O)CN)c(-c3cccc(F)c3)oc12 +CCC(=O)N(c1ccccc1)C1CCN(CCC(C(=O)N2CCCC2)(c2ccccc2)c2ccccc2)CC1 +O=C(COc1ccc(Br)cc1Cl)NC1CCN(Cc2ccccc2)CC1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CCCC(F)(F)C3)ns2)n1 +CN(C(=O)Cc1ccc(CNS(=O)(=O)Cc2ccccc2)cc1)C(CN1CCC(O)C1)c1ccccc1 +COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(C(F)(F)F)cc4)nc2-3)cc1OC1CCCC1 +CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc(NS(C)(=O)=O)cc1 +Cc1ccc(COc2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)cc1 +COc1ccc(Oc2cc(Nc3cc(Cl)ccc3C(N)=O)c(C(F)(F)F)cn2)cc1 +COc1cc(OC)cc(N(CCCc2ncccc2OC)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CCCCCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCN +O=C(Cc1cccc(Cl)n1)Nc1ccc(CCNCC(O)COc2ccccc2)cc1 +Cc1ccc2nc(NC(=O)N3CCN(c4ncc(C(O)C(C)O)cc4F)CC3)sc2c1 +O=C(C=CC#Cc1cccc(O)c1)NC1=C(C(=O)O)CCCC1 +COc1cccc(Cn2cc(C)c3cc(F)cc(C=CC(=O)NS(=O)(=O)c4cc(F)c(F)cc4F)c32)c1 +CN(C)CCC(=O)OCc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F +CC(C)Oc1cccc(-c2c[nH]c3ccc(-c4nnc(NC5CCCNC5)s4)cc23)n1 +OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)c1ccc(-c2ccccc2)nc1 +COC1(COc2cccc3ccc(-c4nnc5cc(C)ccn45)nc23)CCNCC1 +CCc1csc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)n1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2ccc(O)cc12 +Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1-c1ccc(C(F)(F)F)cc1 +COc1cc(C(=O)NCC(c2cccnc2)N2CCN(c3ccc(F)cc3)CC2)cc(OC)c1OC +COc1ccc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1-c1c(Br)cnn1C +O=C(CCCCCn1cc(-c2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)nn1)NO +CC1C(=O)c2nn(C(C)(C)C)cc2OC12CCN(C(=O)c1ccc3[nH]ncc3c1)CC2 +CCN(CC1CCNCC1)c1ccc2c(SC)nn(-c3ccccc3)c2c1 +CCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3ccccc3C(F)(F)F)cc2o1 +Cc1c(COc2ccc(CC(C)NCC(O)c3cc(O)cc(O)c3)cc2)no[n+]1[O-] +O=C(Nc1cccc(Cl)c1N1CCCC1)c1cccc(-c2cc3ccccc3oc2=O)c1 +Cc1cc(CN2CCCC(O)C2)ccc1C(=O)Cn1ncc(OCc2ccccc2)cc1=O +CCOC(=O)CC(C)(O)CC(O)CSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1 +O=C(c1cc(O)c(O)c(O)c1)c1ccc(O)c(O)c1O +CNC(=O)COC(=O)C1CCCN1C(S)=Nc1ccc(S(N)(=O)=O)cc1 +CN1CCC2(c3cccc(O)c3)CCC(=Cc3ccc(Cl)c(Cl)c3)C1C2 +CNCCN1CCC(OCc2ccc(C3CCCCC3)cc2)CC1 +CCc1[nH]c2nc(Sc3cnc4c(c3)c(=O)ncn4C)nc(N3CC4C(N)C4C3)c2c1Cl +COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OCCN1CCCC1 +O=C(NC1CCN(Cc2ccc3sccc3c2)CC1)c1cc(=O)c2ccc(F)cc2o1 +CN1CCN(c2ccc3ncc(C(N)=O)c(Nc4ccc(F)cc4F)c3c2)CC1 +O=C1C2CCCN2C(=O)N1CCCCNCCc1cccc2ccccc12 +CN(C)c1ccc(S(=O)(=O)N(CCC2CC2)c2cc3ccccc3s2)cc1 +Nc1ncc(-c2cc(N3C4CCCC3CCC4)nc(N3CC4CC3C4)n2)cn1 +CCCCCCCCCCCCc1cc(CC(=O)Nc2c(OC)cc(OC)cc2OC)on1 +COc1cc(C(=O)NCN2CCC(c3cccc[n+]3[O-])CC2)ccc1Cl +Cc1ccc(CN(CCNC(=O)c2ccc(CNS(=O)(=O)c3cccc(C)c3)cc2)C(C)C)cc1 +CCCCc1sc(-c2ccc(OCCN3CCCC3)cc2)nc1-c1ccc(Oc2ccc(Cl)cc2)cc1 +O=S(=O)(Nc1ncc(Cl)s1)c1cc(F)c(Oc2ccc(F)cc2-c2cn[nH]c2)cc1F +Cc1cccc(Nc2nc(NC3CCCNC3)ncc2C(N)=O)c1 +CCCCCCCCCCCCc1cn(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccccc2)cn1 +CC1CC(O)C2(O)OC3CC4(C=O)C(CCC5C4CC(O)C4(C)C(C6=CC(=O)OC6)CCC54O)CC3OC2O1 +Cc1nc(NC(=O)CN2CCC(N(N)CC(=O)N3CSCC3C#N)CC2)sc1C +OC1(CN2CCCC2)CCN(c2ncnc3scc(-c4ccccc4)c23)CC1 +CNC(=O)c1cnc(Nc2ccc(OC)c(F)c2)cc1NC(c1ccccc1)C(O)CO +O=C(Nc1ccccc1)N1CCN(Cc2ccc3ccc4cccc5ccc2c3c45)CC1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#CC4CC4)nc31)C(O)C2O +O=C(O)COCC1CCC(COC(=O)N(c2cccc(F)c2)c2ccc(F)c(F)c2)CC1 +CNCCN1CCC(NCc2cccc(OC(F)(F)F)c2)CC1 +Cc1nc(C)c(CNc2nc(OCCCc3ccccn3)nc(Cl)c2C)s1 +C#Cc1cccc(Nc2ncnc3ccc(OCCCCOP(N)(=O)N(CCCl)CCCl)cc23)c1 +CCNC(=O)C(CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 +CNS(=O)(=O)Nc1cccc(Cc2c(C)c3ccc(Oc4nccs4)cc3oc2=O)c1F +O=C(OC1CN2CCC1CC2)N1CCc2ccccc2C1c1ccccc1 +Cc1cc(C(CC(c2ccc(-c3ccc(C(=O)O)cc3)cc2)c2ccccc2C)=NO)ccn1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)C1CC1 +CCc1cc(=O)oc2nc(OCc3ccc(C(F)(F)F)cc3)[nH]c(=O)c12 +CCNC(=O)CCc1nc(-c2ccc(C(C)(C)C)cc2)no1 +CC(C)CCn1c(Cn2c(=O)n(Cc3ccc(CP(=O)(O)O)cc3)c3ccccc32)nc2ccccc21 +CC(C)CC(NC(=O)c1cc2ccccc2s1)C(=O)NC1CCN(CCc2ccc(OC3CCNC3)c(Br)c2)C1 +Cn1nccc1Cc1cnc2c(c1)cc(C(=O)NCc1ccc(Cl)cc1)c(=O)n2CC(=O)N1CC(C)(C)C1 +Cc1cccc2cc(C=CC(=O)c3ccc(I)s3)c(Cl)nc12 +COc1ccnc(Nc2ccc(Cl)c(OCc3ccccc3)c2)n1 +COc1cccc(N2CCN(CCCCNC(=O)c3ccccn3)CC2)n1 +N#Cc1cnc(NC(=O)Nc2ccc(CCNCc3ccccc3Cl)c(Cl)c2)cn1 +Fc1ccc(Cl)cc1C(F)(F)C1CCN(c2nc3cnccc3nc2NC2CC2)CC1 +O=C(NO)c1cc2ccc(NS(=O)(=O)Cc3ccccc3)cc2s1 +CCC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(C=O)CC(C)C +O=C(O)CC(Cc1cc(OCCc2ccc3c(n2)NCCC3)n(CC(=O)O)n1)c1ccc2c(c1)OCO2 +O=C(NO)C1CCS(=O)(=O)N1Cc1ccc(-c2ccccc2)cc1 +COc1ccc2c(c1)CCCC2NC(=O)CCCN1CCN(c2ccccc2OC)CC1 +CC(=Cc1ccc(C(=O)O)cc1)c1ccc(O)c(C2(C)CCCCC2)c1 +NCCCCN1C(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +S=C1Nc2c(oc3ncccc23)C(c2cccc(OCc3cccnc3)c2)N1 +O=C(CCC(=O)N1CCN(C2CCCCCC2)CC1)c1ccc(Cl)cc1 +Cc1ccc(NC(=O)c2ccc(CN3C(=O)C=CC3=O)cc2)cc1Nc1nccc(-c2cccnc2)n1 +CC(=NOC(c1ccc(OCc2nc3ccccc3n2C)cc1)C1CCCCC1)C(=O)O +O=c1[nH]c2c(F)cccc2n1C1CCN(C2CCN(Cc3ccccc3C(F)(F)F)CC2)CC1 +CC(C)CC(CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NC(C(N)=O)C(C)C +Cc1ccc(N(C(=O)OCC2CCC(COCC(=O)O)CC2)c2ccccc2)s1 +COCc1ncc(Cc2ccc3cccc(NS(N)(=O)=O)c3n2)c2cc(OC)c(OC)cc12 +CC(C)C(NC(=O)CCC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF +N#Cc1ccc(-c2ccncc2)c(OCCc2ccccc2)c1 +CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(Oc2ccccc2)cc1 +CN1C(=O)C(N2CCn3cc(Cc4ccccc4)nc3C2=O)COc2ccccc21 +CC(C)CN(NC(=O)OC(C)(C)C)c1ccnc(C#N)n1 +O=c1cc(Cn2c(C3CCCC3)nc3nccnc32)c2ccc(F)c(F)c2[nH]1 +CCCc1ccc(S(=O)(=O)N2CCc3cc(O)ccc3C2c2ccc(OCCN3CCCC3)cc2)cc1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2cc(OCC3CC3)ccc12 +C[S+]([O-])c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(N)CC1 +CC(CN1CC(C)(C)c2cc(F)ccc21)NC(=O)OC(CC1CCCCC1)C(=O)N1CCCCC1 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc(O)cc4)CC3)c2c1 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+O=C(NCC1Cc2ccccc2CN1C(=S)NCC1CCCN1Cc1ccsc1)Nc1ccccc1 +COc1ccc(S(=O)(=O)Oc2ccccc2NC(=O)c2ccncc2)cc1 +COc1cccc(C(=O)N2CCN(C(=O)c3ccc(-c4ccc(C)nc4)cc3)CC2)c1 +O=c1[nH]c(Cc2ccccc2-c2cc(C(F)(F)F)ccn2)nc2c1cnn2C1CCOCC1 +Nc1cnc2ccn(S(=O)(=O)c3c(Cl)nc4sccn34)c2c1 +CC1(C)CCc2c([nH]c3cc(Cl)ccc3c2=O)C1 +CCC(C)C(NC(=O)C(CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1cccc(C(=O)N2CCC(CN)CC2)c1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(NC3CCCC3)cc2n1Cc1ccccn1 +CC(O)CCC(=O)N(c1ccc(-c2ccccc2-c2nn[nH]n2)cc1)C(C(=O)O)C(C)C +Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(-c3ncnc4nc[nH]c34)cc21 +COc1ccc(CNC(=O)N2C(C)CN(Cc3ccccc3)c3cnccc3C2C)cc1 +Cc1nc[nH]c1-c1c2c(=O)n(C)c(=O)n(CC3CC3)c2nn1Cc1ccnc2ccc(Cl)cc12 +CCN(CC)C(=O)N1CCN(C(=O)N2C(=O)C(CCCN=C(N)N)C2C(=O)O)CC1 +CC1C(=O)C(C)(C)Nc2ccc3c(c21)C(=Cc1ccccc1)Oc1ccccc1-3 +Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)[nH]c3ccccc23)cc1C +O=C(CC1(C2COC3CCCC3N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC(CO)CC1 +COc1ccc(C2(C(=O)OCCCN3CCC(c4ccccc4)CC3)CCCC2)cc1 +CN1C(C(=O)O)CSC1c1csc(-c2ccc(N)cc2O)n1 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+CCCCc1c(C(=O)NCc2cncn2C)cnn1-c1ncc(C)c(-c2cccs2)n1 +N#CCN1CCN(c2ccc(C(F)(F)F)cc2)c2ccc(-c3cccc(C(O)CO)n3)cc2C1 +Cc1ccccc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1 +O=S(=O)(c1cccc2ccccc12)N1Cc2ccccc2N(Cc2c[nH]cn2)C(CCc2ccccc2)C1 +NC(Cc1ccc(C(=O)NCCc2ccc(-c3ccccc3)cc2)cc1)C(=O)N1Cc2ccccc2CC1C(=O)O +CCCN1CCC2c3cc4cc(Cl)ccc4nc3C(CC)C3CCCC1C23 +CCCCCc1oc(N)nc1-c1ccc(P(=O)(O)O)o1 +Cc1cc(Nc2ncc(-c3nc(-c4ccccc4)cs3)c(NC3CC(CO)C(O)C3O)n2)ccn1 +NCc1cccc(C2CCN(C(=O)c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)CC2)c1 +N#Cc1c(-c2cccc(NC(=O)CCN)c2)cc(-c2ccc(F)cc2O)nc1NC(=O)c1cccs1 +COc1cc(-c2cccc3[nH]c(-c4n[nH]c5ccccc45)nc23)cc(OC)c1OC +O=C(Nc1nc2cc(Cl)ccc2[nH]1)c1ccc2cc3n(c2c1)CCCNC3=O +COc1ccc(OC)c(Sc2ccc(NC3=NCCN3)cc2)c1 +CC(CS)C(=O)N1CC(NC(=O)C(CS)Cc2ccccc2)CC1C(=O)O +Cc1c(O)ccc2c1OC(c1ccc(OCCN3CCCCC3)cc1)C(c1ccc(O)cc1)S2 +CC(C)Cn1cc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1OCCN1CCCC1 +Cc1cc(C)c(C=C2C(=O)Nc3cc(F)ccc32)[nH]1 +CCCn1c(=O)c2nc(-c3cnn(Cc4ccccc4C)c3)[nH]c2n(CCC)c1=O 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+CN(CCCCCNc1ccc(-c2ccccc2)nn1)Cc1ccccc1 +Fc1ccc(CNc2ncnc3c2cnn3CC(Cl)c2ccc(Br)cc2)cc1 +COC(C)CCOC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +CN(C)CCN1C(=O)c2cccc3c2c(cc2cccc(O)c23)C1=O +Fc1cccc(CNC2=NC(c3ccccc3)C(c3ccccc3)N2)c1 +CC(C)Nc1nc(-c2ccc(S(=O)(=O)CCN3CCCC3)cc2)cc2ncn(C)c(=O)c12 +COc1cc(CC=Cc2ccccc2C=CC(=O)O)ccc1OCC[n+]1c(C)cc(C=CC=Cc2ccc(N(C)C)cc2)cc1C +CC(C)(CO)NC(=O)c1ccc(NC2CC2)c(OCC2CC2)n1 +Cc1ccc(-c2cccc(C=CC(=O)Nc3ccc(C[N+]4(C)CCCCC4)cc3)c2)cc1 +Cc1cc(COc2ccc3c(c2)CN(CC2(c4ccc(F)cc4)NC(=O)NC2=O)C3=O)c2ccccc2n1 +O=C1Cc2c(cccc2N2CCN(Cc3ccccc3)CC2)N1 +CC(N=C(S)NCc1ccc(C(C)(C)C)cc1)c1ccc([N+](=O)[O-])cc1 +CN1CCN(c2ccc(NC(=O)c3ccc(C#N)o3)c(N3CCCC(F)C3)c2)CC1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4ccc(C#N)cc4)CC3)CN(C)C1C2 +COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)c4nnc(C)n4c2)C3=O)c(OC)n1 +CNC(=O)c1c(C(N)=O)nn2c1CCOc1ccc(C#CC(C)(O)c3cc(C)on3)cc1-2 +Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(C(C)C)cc4)cc3=O)cn12 +Nc1nc(N)c2c(OCc3cc4ccccc4cn3)cccc2n1 +O=C1CCc2cc(C(c3ccccc3)n3ccnc3)cc3c2N1CC3 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3ccc(N)nc3)nc21 +O=S(=O)(NCCCCC(CCCc1cccnc1)CCC1N=NN=N1)c1ccc(Cl)cc1 +COC1(C#CC(O)(c2cccs2)c2cccs2)CN2CCC1CC2 +O=C(O)c1ccc(Nc2nc3c(-c4cnn(C5CCCC5)c4)cccn3n2)cc1 +O=P(O)(O)C(F)(F)c1ccc(C(F)(F)P(=O)(O)O)cc1 +Cc1cc(N=S2(=O)CCC2)cc2ncnc(Nc3ccc(Cl)cc3OC(C)C(=O)NC(C)C#N)c12 +CNC(=O)c1ccc(-c2nccnc2C2CN(c3ncc4ccccc4n3)C2)cc1F +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(S(C)(=O)=O)CC3)cc12 +Nc1nnc(CC(=O)NN=Cc2cccc(OCCOc3ccccc3)c2)s1 +CC1Oc2ccc(CN3CCC(N(C)C)CC3)cc2NC1=O +CC(C)n1cc(C#N)c2cc(-c3ncc(C(=O)O)s3)ccc21 +Cc1noc(C)c1S(=O)(=O)N(CCCC(F)(F)F)C1CCC(C(N)Cc2cc(F)ccc2F)CC1 +O=C(C1CCCCO1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +COC(=O)c1cc2cc(S(C)(=O)=O)ccc2n1Cc1ccc(Cl)cc1 +O=C(c1ccc(COc2ccccc2)cc1)c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12 +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(CO)C(=O)O +CCN1C(=O)C(=Cc2cc(-c3ccccc3)n(-c3ccc(Cl)cc3)c2-c2ccccc2)C(=O)N(CC)C1=S +CCC(=O)NCC(C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(C)c12 +O=C(O)c1cc2ccn(Cc3cccc(Cl)c3F)c2cn1 +Nc1cccc2c1CC(O)C(N1CCC(C(=O)c3ccc(Br)s3)CC1)C2 +COc1cc(C=CC(=O)c2cccc(NC(=O)c3cccs3)c2)ccc1O +CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(=O)c3ccccc3)cc12 +CCCN(CCC)C1=CC(=O)C(C(C)(C)C)=CC1=O +COc1ccccc1CCCCN1CCN(Cc2cc3ccccc3o2)CC1 +Clc1ccc2c(NC3CCCCC3Nc3ccnc4cc(Cl)ccc34)ccnc2c1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc(Oc3cccc4[nH]c(=O)[nH]c34)c2)cc1 +CNC(=O)c1cccc(S(=O)(=O)c2ccccc2Cc2c3c(n(CC(=O)O)c2C)CCNC3=O)c1 +NC1CCN(c2cncc(-c3n[nH]c4ccc(-c5c(F)cccc5F)cc34)n2)CC1 +COc1ccc(CCNCC(O)COc2ccc(O)c(NS(C)(=O)=O)c2)cc1 +CC(O)CNc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1 +Cn1cc(C#N)c2ccc(Nc3ncc(-c4ccccc4)o3)cc21 +CC(C)(C)C(=O)OCC1(CO)CC(=Cc2ccc(F)c(Br)c2)C(=O)O1 +CNC(C)C(=O)NC1CCCC2CC3CCN(CCc4ccc(Cl)cc4)CC3N2C1=O +COc1cc(COc2cnc(N)nc2N)ccc1OCCCc1ccccc1 +Clc1cccc2[nH]c3c(c12)CCc1c[nH]nc1-3 +COc1ccccc1S(=O)(=O)c1c[nH]c2cccc(OCC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)c12 +COc1cc(F)ccc1Oc1cc(Cl)ccc1C(=O)Nc1cc[nH]c(=O)c1 +C=CCN1C2CCC1C1CCC2N1C(c1ccc(C(=O)N(CC)CC)cc1)c1cccc(O)c1 +O=C(Nc1ccc(C(=O)N2CCCc3c[nH]c4cccc2c34)c(Cl)c1)c1ccccc1-c1ccccc1 +O=c1cc(N2CCCCC2)oc2c(-c3ccc(-c4ccccc4)s3)cccc12 +Cc1cc(C)c(Oc2cc(NC3CCN(Cc4ccccc4F)CC3)nc3ncnn23)c(C)c1 +Cc1cccc(C)c1N=C1SC(CC(=O)Nc2c(C)cccc2C)C(=O)N1CCc1ccccn1 +NC1CCCCC1NC(=O)c1cn2c(ccc3c(C(F)(F)F)cc(C(F)(F)F)nc32)n1 +COc1ccc(-c2cc(C#N)ccc2C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C)cn1 +COc1ccc(Nc2nnc(SCC3CCCCC3)[nH]2)cc1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc(C(F)(F)F)cc2)nn1 +O=C(NO)c1cnc(NCc2ccccc2-c2ccccc2)nc1 +COc1ccc(C2(c3cncnc3)NC(=N)N(C3CCOCC3)C2=O)cc1 +CNc1nc(C)c(-c2ccnc(Nc3cccc(O)c3)n2)s1 +Cn1cc(-c2ccc(-c3cncc4ccc(N5CCNC5=O)nc34)cc2)cn1 +CC(=O)N1CC(O)CC1CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +CN1CCN(c2nc(NCCCc3ccccc3)nc(NCCc3ccc(O)cc3)n2)CC1 +CCCCC#Cc1nc(NCc2cccc(I)c2)c2ncn(C3SCC(O)C3O)c2n1 +COc1cc(-c2nnc3n2CCCC3c2ccc(Cl)c(C(F)(F)F)c2)ccc1-c1cnc(C)o1 +COC(=O)c1ccc(Br)c(CSc2nc3ccccc3n2CC(=O)O)c1 +CCCNc1cc(NC(=O)c2cccnc2)cc(C(F)(F)F)c1 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+CCCCCCCCCCCCCCCCCCNC(=O)OCCSCCOC(=O)N(Cc1cccc[n+]1CC)C(C)=O +Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(C(F)(F)F)cc1 +N#CCc1ccc(Oc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1 +CN(C)Cc1ccc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc2n1 +CCC(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cn1 +CN(C)CCCNc1cc(-c2cccc(C(F)(F)F)c2)c(C#N)c2nc3ccccc3n12 +COc1cccc(C2CN(c3nc(-c4ccncn4)cc(=O)n3C)CCO2)c1 +Cn1cnc2cc(-c3ccc(N4CCC(O)C4)c(S(C)(=O)=O)c3)nc(NC3CC3)c2c1=O +Cc1ccc(-c2c(C)c(C(=O)Nc3cccc(C)n3)nn2C)cc1 +CC1(C)CNc2cc(O)c(C(=O)N3Cc4ccccc4C3)cc21 +Cc1nc(CCO)c(-c2cc(C(=O)N3CC(c4ccc(C#N)cc4)C3)ccc2C)[nH]1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)O +N#Cc1ccccc1S(=O)(=O)NC1CCC(Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(OC)c3c2)c1F +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(CO)C5)cn3)n2)s1 +O=C(NCCCCCCCCn1cc(-c2cccnc2)nn1)c1ccccc1-c1ccccc1 +O=c1[nH]ccn1-c1cccc(OC2c3ccccc3CC2N2CCCC2)c1 +CC(C)N1CCC(Oc2ccc(N3CCN(C(=O)c4ccc(F)cc4)CC3=O)cc2)CC1 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+C=CC1CN(CCF)C(=O)C2CCCC1N2S(=O)(=O)c1cc(Cl)cc(Cl)c1 +O=C(NCc1nc(Nc2cc(C3CC3)n[nH]2)c2cccn2n1)c1ccc(F)nc1 +Clc1ccccc1Oc1cncc(C2=CC3CNCC(C2)C3)c1 +O=c1[nH]c(CN2CCC(O)CC2)nc2c1sc1ccc(Cl)cc12 +O=C(c1ccc(O)cc1O)N(Cc1ccccc1)c1ccccc1 +O=C1NCCc2[nH]c(-c3ccnc(Nc4ccccc4)n3)cc21 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(N4CCOCC4)nc23)N1 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCC(O)CC +Cc1cc(C(F)(F)F)nc(N2C(=O)CSC2c2c(Br)cccc2Br)n1 +O=C(CCCN1CCN(CCC2CCc3ccccc3C2=O)CC1)c1ccc(F)cc1 +O=C(O)CC(O)(CC(O)CCCCCCc1ccc(Cl)cc1Cl)C(=O)O +CC12CCC3c4ccc(CBr)cc4CCC3C1CC(Cc1cccc(C(N)=O)c1)C2O +Cn1cc(C2CCC(Oc3nccnc3-c3cncnc3)CC2)c2ncccc21 +COC(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)(c1cccc(F)c1)c1cccc(F)c1 +Cc1ccc(-c2noc(C3CC(N)C3)n2)cc1NC(=O)c1cnc2ccccn12 +Nc1nc(N2CC3CC2CN3)c2sc3ccc(Br)cc3c2n1 +Cc1nc(-c2cc3cc(-c4ccnc(C(=O)NCc5ccncc5)c4)ccc3[nH]2)no1 +O=C(NCCCCCC(=O)N1Cc2ccccc2CC1C(=O)N1CCCC1)OCc1ccccc1 +CCC(CC)OC1C=C(C(=O)O)CC(NCC=Cc2ccccc2)C1NC(C)=O +CCN(CC)CC(=O)N1c2ccccc2CCc2ccc(NC(=O)OC(C)C)cc21 +O=C1CCc2c(Oc3ccc4c(c3)C3C(O4)C3c3nc4c(Cl)cc(C(F)(F)F)cc4[nH]3)ccnc2N1 +Cc1c(C(C)C)c(=O)on1C(=O)N1CCCC(CO)C1 +CS(=O)(=O)c1cccc(Nc2nccc(N(CCO)c3c(Cl)ccc4c3OCO4)n2)c1 +Cc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1 +N#CC(Cc1ccc(-c2csc(C(N)=O)c2)cc1F)NC(=O)C12CCC(CC1)CN2 +CS(=O)(=O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ncn2)c1 +Cn1ccc(S(=O)(=O)N2CCC(N3CC(CC#N)(n4cc(-c5ncnc6[nH]ccc56)cn4)C3)CC2)n1 +FC(F)COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCNCC4)nc12 +CC(NC(=O)C1CC1)c1ccc(OC2CCN(c3ccnc(N4CCOCC4)n3)C2)cc1 +CCS(=O)(=O)c1ccc(OC)c(-c2ccc(C(C)N3CCCC3)[nH]2)c1 +CCNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)nc3c2C(=O)N(C2CCN(C)CC2)CC(C)(C)O3)cc1 +CC(O)(c1ccc(C(=O)N(C2CC2)C2CCC(C#N)(c3ccccc3)CC2)cc1)C(F)(F)F +CCCOc1c(NC(=O)N(O)CC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC +Cn1c(=O)cnn(CCCCN2CCN(c3ccccc3OCCF)CC2)c1=O +Fc1cc(-c2ccccc2)cc(-n2nnc(-c3ccccn3)n2)c1 +COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 +CCCCN(C)C(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C 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+CCc1cc(CCc2nc3cccc(C)c3o2)c(O)nc1C +Nc1c(C(=O)c2cc3ccccc3[nH]2)cnn1-c1ccc2[nH]c(C(F)(F)F)nc2c1 +CCNc1nc2ccccc2n1-c1nc2c(c(C(C)(C)S(C)(=O)=O)n1)OCC1COCCN21 +CC(C)=CCN(Cc1ccc2ncn(C)c(=O)c2c1)c1ccc(C(=O)NCc2cccnc2)cc1 +Cn1c2c(c3ccccc31)CN(CCCC(=O)c1ccc(F)cc1)CC2 +NC(=O)n1cc(NC(=O)N2CC(F)CC2CNS(=O)(=O)c2ccccc2)c2ccccc21 +CC(C)n1nc(-c2cnc3[nH]cc(C(F)(F)F)c3c2)cc1C1CN(C2COC2)C1 +Cc1ccc(-n2nc(-c3ccc(NS(=O)(=O)c4cccc(N(C)C)c4)cc3)cc2N)cc1 +COc1cccc(CNCC(C)n2c(=O)c(-c3cccc(OC)c3)c(C)n(Cc3c(F)cccc3F)c2=O)c1 +COc1ccc(-c2cnn(C3CCN(CC(=O)NCc4nc5c(c(=O)[nH]4)COCC5)CC3)c2)cc1 +O=C(c1ccccc1)N1CCC(c2ccccc2)(c2nccn2Cc2ccccc2)CC1 +C=C(CN(C)C)C(=O)c1ccc(OS(=O)(=O)c2ccc(C(=O)O)cc2)cc1 +Cc1cc(C2CCN(S(=O)(=O)C(C)(C)C(=O)NO)CC2)ccc1-c1cccc(OCCN(C)C)c1 +Cc1cc(-c2nc(-c3ccc(F)c(OCC4(C)COC4)c3)n3c2CCOC(C)C3)cc(C)n1 +O=C(NCCF)Nc1ccc(-c2nc(C3=CCOCC3)c3cnn(CC(F)(F)F)c3n2)cc1 +Nc1n[nH]c2c1c(Nc1ccc(C(=O)O)cc1)nc1ccccc12 +COc1ccccc1-c1cc2nnc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nc2cc1C +O=C(CC(Nc1ccc([N+](=O)[O-])cc1)c1cccc(F)c1)c1ccccc1 +COc1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1OC +COc1cccc(-c2c(Cc3ccc(C=CC(=O)O)cc3)c3ccc(O)cc3oc2=O)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(C(=O)Nc2ccccc2)cc1 +OC1CCN(Cc2cccc(I)c2)CC1N1CCC2(C=Cc3ccccc32)CC1 +NC(=O)C(c1ccccc1F)N1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)C1 +COc1ccc2[nH]cc(CCCN3CCN(CCCc4c[nH]c5ccc(OC)cc45)CC3)c2c1 +NS(=O)(=O)c1ccc(Nc2nc(Cl)nc(Nc3ccccc3)n2)cc1 +NCCCN1N=C(C=Cc2ccc(O)cc2)c2ccccc2N(Cc2ccc(-c3ccccc3)cc2)C1=O +COc1cc(-c2cnc(N)c(-c3ccc(C(N)=O)cc3)c2)ccc1O +Cc1c(C2CCN(C)CC2)[nH]c(-c2ccc(F)cc2)c1-c1ccncc1 +O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1 +Cn1ccc(-c2ccc(Nc3nn(C4(CC#N)CCN(C(=O)OC(C)(C)C)CC4)cc3C(N)=O)cc2)n1 +COc1c(OCC(C)(C)O)ncnc1N1CCC(Oc2ccc(C(C)NC(C)=O)cc2)C1 +CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)cc2Cl)n2nccc2N1 +NC(=O)c1cccc(Oc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)n2)c1 +Cc1cc(COc2ccc(S(=O)(=O)CC3(CC(=O)NO)CCN(C)C3)cc2)c2ccccc2n1 +CC(C)NC(C)c1nc2c(C(N)=O)cccc2[nH]1 +O=C(NCC(NS(=O)(=O)c1cccs1)C(=O)O)c1ccc2c(c1)C(=O)N(CCC1CCNCC1)C2 +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CC(=O)O)CC(O)CC1O +Cc1ccccc1-n1[nH]c2cc(=O)n(Cc3ccccn3)c(C)c2c1=O +O=C(CCCCCNC(=O)NC(=O)c1cccc([N+](=O)[O-])c1)NO +CCCNc1ncc2c(n1)c(Nc1ccccc1)nc1cc(C(=O)O)ccc12 +NCc1ccc(NC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)nc1 +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(Nc2ccc(CCC(=O)NCCCN3CCN(C)CC3)cc2)n1 +Cc1c(Nc2c(C#N)cncc2C=Cc2ccc(S(=O)(=O)N(C(C)C)C(C)C)cc2)ccc2[nH]ccc12 +CC(=O)NC1CCC2(C)C(CCC3C4CC=C(c5cccnc5)C4(C)CCC32)C1 +CC(=O)N(C1=C(Cl)C(=O)c2ccccc2C1=O)c1ccc(C(=O)O)cc1 +c1ccc(N2CCN(CCC3CCC(c4c[nH]c5ccccc45)CC3)CC2)cc1 +O=C(O)c1ccc2c(c1)nc(Nc1ccccc1)c1nc(NCCCN3CCOCC3)ncc12 +COc1ccc(S(=O)(=O)N2CCOCC2)cc1-c1ccc(CN2CCCCCC2c2ccccc2)[nH]1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(C#N)cc3)c2)c2cnccc21 +CCCn1c(=O)c2nc(-c3cccn3C)[nH]c2n(CCC)c1=O +O=C(Nc1ncnc2[nH]cnc12)c1ccc(-c2ccc(-n3cccc3)cc2)cc1 +Fc1cccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)c1F +Cc1cc(Cl)ccc1C1=CC(C)(C)Oc2cc(NS(C)(=O)=O)ccc21 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+CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C1NC=C(CCc2ccccc2)S1 +CN(C)c1ccc(C(=O)Oc2ccc3nc(S(N)(=O)=O)sc3c2)cc1 +CN(C)C1CN(C(=O)C(COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)C1 +N#Cc1c(Cl)cccc1S(=O)(=O)Nc1ccc(-c2ccc3c(N)n[nH]c3c2)cc1 +Cc1cc(-c2nc(C3CC3)no2)cc(Oc2ccc3c(c2)N(S(=O)(=O)c2ccc(Cl)cc2)CCC3)n1 +O=C(OCCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)c1cc(O)c(O)c(O)c1 +CS(=O)(=O)c1ccc2c(c1)c1c(n2Cc2ccc(Cl)cc2)C(CC(=O)O)CC1 +COc1ccc(CCCCOc2ccc(CSc3c(Cl)cccc3Cl)nc2C=CC(=O)O)cc1 +CCc1ncc(Cc2ccc3cccc(O)c3n2)c2cc(OC)c(OC)cc12 +COc1ncc(-c2ccc3nc(NC(=O)NCCN4CCCCC4)sc3c2)cc1NS(=O)(=O)c1ccc(F)cc1 +O=C(O)c1ccc(CN(CCCCc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 +O=C(Nc1ccc(Cl)c(Nc2nccc(-c3cccnc3)n2)c1)c1ccccc1 +Cc1ccc(S(=O)(=O)NC(Cc2cccc(C(=N)N)c2)C(=O)N2CCN(C(=O)NCCc3ccccc3)CC2)cc1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c4c(ccc3nc2-1)OCCN4CC#N +CC(C)(C)N1CCC(Oc2cc(-c3ccc(F)cc3F)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c2)CC1 +COc1cc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)ccc1F 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+O=C(NC1CCCCN(Cc2ccccn2)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +COc1c(F)cc(CNc2c3c(nc4ccc(C#N)cc24)CCN(C(C)=O)C3)cc1Cl +CCN1Cc2ccc(NC(=O)C(F)(F)F)cc2-c2ccccc21 +COC(=O)C1(c2ccccc2)CCN(CCCCCN2C(C)=NC(C)=C(C(N)=O)C2c2ccc(F)cc2F)CC1 +COC(=O)C1CCCN1C(=O)c1cccc(C(=O)N2CCCC2C(=O)N2CCCC2)c1 +O=C(c1cccnc1)n1nc(NC2CCN(Cc3ccc4c(c3)OCO4)CC2)c2cc(Cl)ccc21 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)N1CCCCN1C#N +CC(C)c1ccc(-c2ccc3c4[nH]ncc4c(=O)n(CC(F)(F)F)c3c2)c(Cl)n1 +Cn1ccc(-c2cc3c(-c4cccc(-n5ccc6cc(C7CC7)cc(F)c6c5=O)c4CO)ccnc3[nH]2)n1 +CCOC(=O)c1cn2ncnc(Nc3cccc(C(=O)NOC)c3)c2c1C(C)C +N=C(N)c1ccc2oc(CCCCCCCCCCCc3cc4cc(C(=N)N)ccc4o3)cc2c1 +CCc1cc(NCc2ccc3c(-c4nnn[nH]4)cc4ccccc4c(=O)c3c2)n2nccc2n1 +CCN(CC)c1ccc2nc3c4ccccc4c(=O)cc-3oc2c1 +CC(=O)N1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccc(N5CCN(C(C)=O)CC5)cc4)n3)cc2)CC1 +Cc1cc(-c2cccc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)c2)on1 +Nc1ccc(CCCCN2C3CCC2CC(OC(c2ccc(F)cc2)c2ccc(F)cc2)C3)cc1 +O=C(Nc1ccccc1)Nc1ccsc1-c1nc(O)c(O)c(C(=O)O)n1 +O=C(c1ccc2c(c1)ncn2-c1ccc(Cl)cc1)N1CCCCC1 +CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCC34CC5CC(CC(C5)C3)C4)cc2C1=[N+](C)[O-] +Cc1cnn(CCOc2cc(Cl)cc(Cl)c2-c2nc(N)nc3c2CN(C(=O)NC24CC(C2)C4)C3)c1 +CC1=C(C)C(=O)C(C(CCCCC(=O)O)c2cccnc2)=C(C)C1=O +CC1(C)OOC2(CCC(C(=O)Nc3ccc4ncnc(Nc5cccc(Cl)c5)c4c3)CC2)OO1 +CCC(CC)CN1CCC(S(=O)(=O)CCCOc2ccc3[nH]c4nc(O)nc-4cc3c2)CC1 +O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2[nH]ncc21 +CCS(=O)(=O)CCOC12CCCCC1(S(=O)(=O)c1ccc(Cl)cc1)c1c(F)ccc(F)c1OC2 +Cc1cc2nc(NC(=O)N3CCN(C(=O)c4cccc(F)c4)CC3)sc2cc1C +Cc1cc(C(O)c2ccccc2Br)nc(Nc2ccc(C#N)cc2)n1 +Cc1ccc(N(C(=O)NCCCN2CCC3(CCc4ccccc43)CC2)c2ccc(F)c(F)c2)cc1 +CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)Cc3c(C)noc3C)cc2F)CC1 +CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(C3CC3)[nH]2)c1O +CN(C)C=NC(=O)c1cnn2c1n[n+]([O-])c1ccc(OCc3ccncc3)cc12 +CCOC(=O)c1cc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O +O=C(Nc1nc(-c2ccccc2)cs1)c1ccc([N+](=O)[O-])cc1 +CN1CCC(C(=O)N2Cc3c(NC(=O)c4cccc(F)c4)n[nH]c3C2(C)C)CC1 +Cc1cc(-n2cc(C(F)(F)F)cn2)ccc1C(Nc1ccc(C(=O)NCCC(=O)O)cn1)C1CCCCC1 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+CCCOC(=O)C=CC(=O)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +O=C(C1CN(S(=O)(=O)c2cccc3cnccc23)C1)N1CCN(c2ccnc(Cl)c2)CC1 +O=C(O)c1ccc2c(c1)nc(Oc1cccc(Cl)c1)c1ccncc12 +COc1cc(-c2nnc3n(C(C)c4ccc(F)cc4)cc(C(C)(F)F)cc2-3)ccc1-n1cnc(C)c1 +CC1(c2nc(NC(=O)c3ncc(F)cc3N)ccc2F)N=C(N)OCC1(F)F +CCOC(=O)CC1CC(n2cc(-c3ccccc3)c3c(N)ncnc32)CN1 +Cc1cc(C)cc(-c2cc(-c3ccc(F)cc3)c(C=CC3CC(O)CC(=O)O3)c(C(C)C)n2)c1 +Cc1cc(Nc2nccc(OCCO)n2)cc(-c2cnc(C3(O)CCC(C(N)=O)C(C)(C)C3)s2)c1 +CC1CCCN1c1ccc(C(=O)N2CCC(F)(F)C(=CC(=O)NCc3ccccn3)c3ccccc32)c(Cl)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCCC4CC4)c3)C2)cc1 +CCn1cc2cc(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)ccc2n1 +CSC1OC(c2ccc(Cl)c(Cc3ccc(OCCCC(=O)NC(C)(C)CO)cc3)c2)C(O)C(O)C1O +O=C(c1ccc(Cn2ccc3cc(Cl)ccc32)cc1)N1CCC(N2CCCC2)C1 +CN1CCN(Cc2ccc(NC(=O)Nc3ccc(-c4nc(N5CCOCC5)nc(N5C6CCC5COC6)n4)cc3)cc2)CC1 +COc1ccc2nc(C(F)(F)F)nc(NN3C(=O)C=C(C)C3=O)c2c1 +CCc1cc2c(C(=O)c3cc(Br)c(O)c(Br)c3)c(OC)ccc2o1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2cccc(Cl)c2)cc1 +CCN(Cc1cc(C(F)(F)F)ccc1-c1nn(CC(=O)O)c2cccc(F)c12)C(=O)C1CC1 +O=c1[nH]c2c(O)ccc(C(O)CNCCCSCCCOCCc3ccccc3)c2s1 +O=c1n(-c2ccccc2)nc2c(NC3CCCCC3)nc3ncccc3n12 +Fc1cccc(COc2ccc(Nc3ncnc4ccc(-c5ccc(CN6CCNCC6)o5)cc34)cc2Cl)c1 +CCCCCCCCCCCOc1ccccc1CCC(=O)OCCCOP(=O)(O)OCC(N)C(=O)O +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccc(F)cc1Cl)CC2 +C=C(C)n1c(=O)n(CCN2CCC(N(C(=O)CC)c3cccc(Cl)c3)CC2)c2ccccc21 +O=C1CCC2CN(CC3CC3)CCC2(c2cccc(O)c2)C1 +CC(C)(C)c1ccc(C(=O)Nc2[nH]nc3c2CN(C(=O)Cc2ccsc2)C3)cc1 +CCc1c(Sc2cc(OC)ccc2OC)[nH]c2nc(N)nc(N)c12 +CC(C)(C)OC(=O)NC(CO)C(=O)N1CC2(CC1C(=O)NCCCCCC(=O)NO)SCCS2 +OC1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCOC5)c4n3)nc2)C1 +COc1ccc(CSc2nc(C(=O)c3ccccc3F)c(C(C)C)c(=O)[nH]2)cc1 +Oc1ccc2[nH]c3c(c2c1)CCN(CCCCc1ccccc1)C3 +CCCN(c1ccccc1Cl)S(=O)(=O)c1ccc(O)c(C)c1 +C=CC(=O)Nc1cccc(CNc2nc(Nc3cnn(CCN4CCOCC4)c3)ncc2Cl)c1 +CC(c1ccncc1)N1CCN(S(=O)(=O)c2ccc(C(C)(C)C)cc2)C(C)C1 +O=C(Cc1ccc(O)cc1)NN=C1C(=O)Nc2cccc(-c3cccc(F)c3)c21 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+CCCCCCCCn1cc(CN(C)C(C)C)c2cc(-c3cccc(C)c3)ccc21 +CC(C)CC(NC(=O)N1CCOCC1)C(=O)NC(C=O)CCc1ccccc1 +COC(=O)c1ccc(-c2ccc(CN3CCc4cc(OC)c(OC)cc4C3)cc2)cc1NC(=O)c1ccc2ccccc2n1 +COc1ccc(Cc2nnc(NC(=O)c3ccc(C4CCC(CC(=O)O)CC4)cc3)s2)cc1 +O=C(Cc1cc(Br)cc(Br)c1OC(=O)c1ccccc1Cl)NC1CCOC1=O +CCN(CC)c1ccc(Nc2cc(N(CCCN(C)C)C(=O)Nc3c(C)cccc3Cl)ncn2)cc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2CC)n2c1COCC2)c1ccc(C(F)(F)F)nc1 +COc1ccc(NC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)NO)cc1 +O=C1NC(=O)c2c1c(-c1ccsc1)cc1[nH]c3ccc(O)cc3c21 +CC(C)[S+]([O-])c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N +Cc1cc([Se]Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OC(C)C(=O)O +Cc1noc(C)c1Cn1cc(N2C(=O)N(CCO)C(C)(C)C2=O)cn1 +COCCN=c1c(O)c(O)c1=NC(Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)C(=O)O +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2ccc(Cl)c(Cl)c2)cc1 +COc1ccc(C=CC(=O)c2ccc(Cl)cc2Cl)c(OC)c1 +c1ccc(-c2nc3c(cnc4ccccc43)[nH]2)cc1 +CC1=CCCC2(C)OC2C(O)C2CCC(C)C(C)(CC1)C2COC(=O)N(C)C +CC1CN(CC(Cc2ccccc2)C(=O)NC(CCc2ccccc2)C(=O)O)CCC1(C)c1cccc(O)c1 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3cc(F)c(N)c(-c4ccoc4)c3)C2O)c1 +CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C(C)O +O=C(OCC12CCN(CC1)CC2)c1c[nH]c2ccc(F)c(Cl)c12 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(C(=O)OCC2CC2(F)F)CC1 +COC(=O)C1(c2cccc(Oc3ccc(C)cc3)c2)CC1C(=O)NO +CC(=O)NC1C(NC(=N)N)C=C(C(=O)NC(CCC(=O)O)C(=O)O)OC1C(O)C(O)CO +CN1CCC(N2Cc3cccc(C(N)=O)c3C2=O)CC1 +CCCCCCCCS(=O)(=O)C(C)(Cc1ccccc1)C(=O)NO +CCNC(=O)Nc1nc2ccc(-c3cccc(C#N)c3)cc2[nH]1 +COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OC +O=C(O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)NCCc2ccc(Cl)cc2)co1 +O=C(Cc1ccccc1)NC(=S)Nc1ccc(Oc2ccnc3cc(-c4nncs4)sc23)c(F)c1 +CC(C)(COc1ccc(-c2cnc(-c3ncc(C(F)(F)F)[nH]3)c(F)c2)cn1)C(=O)O +COc1ccc(S(=O)(=O)Nc2cc(-c3ccc4nc(NC(C)=O)sc4c3)cnc2Cl)cc1 +Oc1cccc(OCC(O)CNC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)c1 +c1ncc(-c2cc3c(cn2)[nH]c2ncc(-c4ccc(CN5CCCCC5)cc4)cc23)cn1 +CC1=NC(C)=C(C(=O)OCCN2C(=O)c3ccccc3S2(=O)=O)C(c2ccccc2Cl)C1=C(O)OC(C)(C)C +Cn1cnc(-c2ccc3c(c2)c(C2CCN(CCn4c(=O)[nH]c5ccccc5c4=O)CC2)cn3-c2ccc(F)cc2)n1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCCF)cc2)cc1)P(=O)(O)O +CCCCCC1=NN(C(=O)NCC2CCC3CC2C3(C)C)CC1c1ccccc1 +Cc1[nH]c(C2Cc3c([nH]c4ccccc34)C(C3CCOCC3)N2)nc1-c1ccccc1 +Nc1ccc(-c2ccc3ncc4ccc(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 +CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc(Cl)s3)ccc21 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(-c2ccccc2OC)n1 +Cc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc(Cl)c(Cl)c2)ccc1OCCN1C(=O)CCC1=O +Cc1ccc(C2=C(c3nnn[nH]3)C(=O)NC(C)(c3ccc(C)cc3)C2)cc1 +COc1ccc(-c2ccn(-c3ccc(O)c([N+](=O)[O-])c3)c2-c2ccc(C(N)=O)cc2C)cc1 +CCCCN(CC(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)c1ccc2oc3ccccc3c2c1 +NCc1cccc(C2CCN(C(=O)c3ccc(C#Cc4ccccc4F)o3)CC2)c1 +Cc1cncc(-c2cc3c(cn2)cnn3-c2cccc(N3CCC(N)CC3)n2)n1 +CN1Cc2c(C3=CC4CCCC(C3)N4CC(=O)O)[nH]c3nccc(c23)-c2cc(F)ccc21 +Oc1ccc2c(c1)OCC1c3cc4c(cc3OC21)OCO4 +CC(C)N1CCC(COc2ccc(NC(=O)Nc3cccnc3Oc3ccccc3C(C)(C)C)c(F)c2)CC1 +O=C(O)c1cnc(Sc2nnc(Sc3ncc(C(=O)O)s3)s2)s1 +CCC(C)c1ccc(Oc2ccccc2S(=O)(=O)NC(C=O)C(=O)O)cc1C +Cn1nccc1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCC1 +CN(C)c1ccc(-c2nc(C(F)(F)F)cn2-c2ccc(S(C)(=O)=O)cc2)cc1Cl +O=C(c1ccccc1)C(Cc1ccc(C(F)(F)P(=O)(O)O)c(Br)c1)c1ccccc1 +CCS(=O)(=O)c1ncn2c1Cn1ncnc1-c1cc(Cl)ccc1-2 +COc1cc(C2c3cc4c(cc3C(n3cc(C(=O)Nc5ccccc5Cl)nn3)C3COC(=O)C23)OCO4)cc(OC)c1OC +Cn1cc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccc(Cl)c(Cl)c2)C(N)CC3)cn1 +CC(c1ccccc1)C(C(=O)O)C(Cc1ccccc1)C(=O)O +CC(=O)NC(C)c1ccc(OC2CCN(c3cccc(N(C)CC(F)F)n3)C2)cc1 +Cc1cc(COc2ccc(S(=O)(=O)NC3CN(C=O)CCC3C(=O)NO)cc2)c2ccccc2n1 +O=c1c(N(Cc2ccccc2)S(=O)(=O)c2ccc(Oc3ccccc3)cc2)cccn1O +COc1c(OCC2CC(F)(F)C2)ccc2c1CCN(Cc1ccc(C(C)NC(=O)C3CC3)cc1)C2 +CN(C)Cc1ccc2ccc(Cl)c(C3=C(c4cn(C)c5ccccc45)C(=O)NC3=O)c2c1 +Cc1nc2c(N3CCOCC3)ncnc2n1Cc1ccc(-c2ccncc2)cc1 +CNC(C)C(=O)NC(C(=O)NC1CC2CCC1N(CCc1ccccc1)C2)C1CCCCC1 +O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1NC(=O)c1scc(CN2CCSCC2)c1Cl +Cc1cnc2[nH]cc(Cc3cnc(NCc4ccc(C(F)(F)F)nc4)c(F)c3)c2c1 +O=C(NC1CCCCC1)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 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+COc1ccc2[nH]c3c(N4CCN(CCc5ccc(F)c(F)c5)CC4)ncnc3c2c1[N+](=O)[O-] +CC(C)OC(=O)c1c(O)cc(OCCN2CCOCC2)cc1CCCN1C(=O)C=CC1=O +COC1C=CC=C(C)C(=O)Nc2ccc(O)c(c2)CC(C)CC(OC)C(O)C(C)C=C(C)C1OC(N)=O +Cc1cc(C)c(Sc2cn(C)c(=O)c(Nc3ccc(C#N)cc3)n2)c(C)c1 +O=C1NC(=O)C(c2ccc(Oc3ccc(Br)cc3)cc2)(N2CCN(c3ccc(I)cc3)CC2)C(=O)N1 +CCc1ccc(CN2CCC(N3Cc4cccc(C(N)=O)c4C3=O)CC2)cc1 +COc1cccc2c(C(=O)NCc3cccc(COc4ccccc4F)n3)nc(N)nc12 +COc1ccc2nc(C)cc(N3CCC(NC(=S)Nc4ccc(Cl)cc4)CC3)c2c1 +O=C(c1ccccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1)N1CCOCC1 +CCNc1nc(C2CC(C)CN2C(=O)C(O)C(O)C(=O)NC(C)c2ccc(-n3cccn3)cc2)cs1 +Cc1ccc(-c2noc(C3CC4(C3)OCCO4)n2)cc1NC(=O)c1cnc2ccccn12 +Cc1ccc(C)c(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +COc1cc(C=CC(=O)OCCc2cccc(O)c2)ccc1O +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccnc(C(F)(F)F)c3)cn2CCN2CCC2)CC1 +Nc1ccc(-c2cccs2)cc1NC(=O)c1cnc2c(C3CC3)c(N3CCNCC3)ccc2c1 +Cc1ccc2cc(-c3n[nH]c4cccnc34)[nH]c2c1 +N#CCOc1cccc(C#Cc2ccc(CCC(=O)O)cc2)c1 +Cc1cccc2cc(Cn3nc(C#CC(C)O)c4c(N)ncnc43)n(-c3ccccc3O)c(=O)c12 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+Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(Cn5ncc6cnccc65)C4)cc23)ccn1 +Cc1cccc2nc(Cn3cnc4ccccc43)cc(=O)n12 +Cc1n[nH]cc1-c1cc2nc(CN3CCC(F)C3)[nH]c(=O)c2s1 +COc1ccc(C(C)C)cc1C1COCC2(C1)OCCNC2c1ccc(F)cc1 +N#Cc1cc(F)cc(S(=O)(=O)c2cnc3cc(Cl)ccc3c2N2CCC(CO)CC2)c1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)nn2C)cc1Nc1ncnc2cnc(N(C)CC3CCCCO3)nc12 +CCCCCCCCNC(=O)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)c1c(F)cc(F)cc1F +NC(C(=O)N1CCCC1)C1CCC(NS(=O)(=O)c2ccc(C(=O)O)cc2)C1 +N#CCNC(=O)Cc1nnc(Cc2nc3c(Br)cccc3s2)o1 +Cc1cc(C(F)(F)C(F)(F)F)ccc1NC(=O)c1cccc(I)c1C(=O)NC(C)C +CN(C)c1ccc2c(c1)OC(N)=C(C#N)C2c1ccc(N(C)C)c2ccccc12 +COc1ccccc1Cc1sc(NCc2ccc3c(c2)CCO3)nc1-c1ccc(Cl)cc1Cl +CCN(C)CC(=O)c1ccc(OC2Cc3cc(OC)c(OC)cc3C2=O)cc1 +CNc1ccc2c(c1)C(C#CC(C)C)(C(F)(F)F)OC(=O)N2 +N#Cc1ccc(-c2cc(NCC(O)c3ccccc3)ncn2)cc1 +CCS(=O)(=O)NC1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)CC1 +CC(C)CC(N)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CN)CC1 +NC1=NCC(Cc2cccc(C(F)(F)F)c2)C(N)=N1 +Cc1ccc(C(=O)C(=O)c2ccccc2)cc1[N+](=O)[O-] +CCS(=N)(=O)c1ccc(Nc2ncc(Br)c(NC(COC)C(C)O)n2)cc1 +Cc1ccc(-c2cnc(N(CCOc3ccccc3)Cc3ccc(C(=O)NO)cc3)s2)cc1 +Clc1ccc(C(c2ccc(Cl)cc2)(c2cc[nH]n2)n2ccnc2)cc1 +O=C(Nc1ccc(-c2ccncc2)c(-c2ccncc2)n1)C1CC1 +CN1CC2(CCN(C(=O)Nc3cc(F)cc(F)c3)CC2)C1c1ccc(Cl)cc1 +CC(CNC(=O)c1cccn2c(=O)c3cc4ccccc4cc3nc12)N(C)C +O=C(NCC1CCCCN1)C1C(C(=O)Nc2ncc(Br)s2)C2CCC1C21CC1 +CCCOC(=O)N1CCc2c(OCCc3nc(-c4ccccc4)oc3C)ccc(CCC(=O)O)c2C1 +O=C(Nc1sc2c(c1C(=O)N1CCOCC1)CCOC2)c1c(Cl)cccc1Cl +Cc1cccc(C)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)CC(F)(F)C1 +CCCCC(NC(=O)N1CCOCC1)C(=O)NC(C#N)CCc1ccccc1 +NCCCCCC(=O)N1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 +CSc1cccc(N(C)C(=N)Nc2cc([S+](C)[O-])ccc2Cl)c1 +Cc1cc(-c2cn3ncc(C(N)=O)c(NC4CN(C(=O)C5(C#N)CC5)CC4C)c3n2)ccn1 +CCCN(CCC)C(=O)c1c(CC)c(N2CCN(C)CC2)nc2ccccc12 +CCN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(C(F)(F)F)cc2)[nH]c2ccccc12 +CN(C)CCc1ccc(Nc2ncc3c(n2)N2CCC(=O)N2C(c2c(Cl)cccc2Cl)=C3)cc1 +COc1ccccc1C1CN(c2nc(-c3ccncc3)cc(=O)n2C)CCN1 +Nc1ccc(C(=O)OC2COC3C(OC(=O)NCc4ccccc4)COC23)cc1 +N#CCCNC(=O)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cccc(F)c3)o2)c1 +COc1cccc(CNCCCNc2ccnc3cc(Oc4cccc(N(C)C)c4)ccc23)c1O +O=C(Nc1ccc(C(=O)NCCN2CCCC2)cc1)Nc1ccc(C(F)(F)F)cc1 +c1ccc2c(c1)Cn1nc(Cc3nc4c(s3)CCCC4)nc1-2 +COc1cc(Nc2c(C#N)cnc3cc(C=Cc4cccnc4)ccc23)c(Cl)cc1Cl +O=C1c2ccccc2C(=O)N1CCCCN1CCN2c3ccccc3Cc3ccccc3C2C1 +O=C(Nc1ccc([N+](=O)[O-])cc1)OCCN1C(=O)c2ccccc2C1=O +CC(O)C(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1c(F)cccc1F +O=C(OCC1CCCC(c2cc(F)cc(F)c2)N1S(=O)(=O)c1ccc(Cl)cc1)N1CCC(N2CCCCC2)CC1 +CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2ccccc2)n1 +CCCc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)OCC +CCOC(=O)CCC(=O)c1ccc(-c2cc3ncn(C)c(=O)c3c(N3CCC(CO)C3)n2)cc1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(C(O)c2ccc(Cl)cc2)CC1 +CCc1nnc(SCC(=O)Nc2ccc(C)cc2Br)n1-c1ccc(C)cc1 +C=C(C)Cn1ccc2c(Oc3ccc(N(C)C)cc3)ncnc21 +NCCCCn1c(SCCc2c[nH]c3ccccc23)nnc1-c1ccc2ccccc2n1 +COc1cc(-c2nc3ccc(Cl)cn3c2NC2CCCCC2)ccc1OCCCNC(=O)Nc1ccc(C(F)(F)F)cc1 +CCN(CC)CCCCCC(=O)Nc1ccc(C(=O)Nc2nccs2)cc1 +CN1CCN(c2ccc3c(C(=O)NCC(c4cnc(C(F)(F)F)nc4)N4CCC(F)(F)CC4)c(Cl)ccc3n2)CC1 +O=c1[nH]c(=O)n(C(CCc2ccc(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc2)c2ccccc2)o1 +Cc1ccc(Nc2ncnc3cc(OC(C)C)c4c(c23)OCCO4)cc1[N+](=O)[O-] +Cc1cc(CNc2nccc(Nc3cc(CCc4ccccc4)[nH]n3)n2)on1 +C=C(C)C(CC)CN1CCC(CNC(=O)c2ccc3cc(Cl)ccc3c2)NC(CCN2CCCCC2)C1=O +CCOC(=O)N1CCC(CN2CCC(N3C(=O)Cc4ccccc43)C2)CC1 +CCOC(=O)C1CCN(C(=O)C(Cc2c[nH]c3ccccc23)NC(=O)Nc2ccc(Br)cc2)CC1 +O=C1C2CCCN2C(=O)N1CCCN1CCN(c2cccc(Cl)c2)CC1 +NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 +COc1cccc(-n2nnc(-c3ccccc3NC(=O)Nc3ccc(NC(=O)CBr)cc3)n2)c1 +COc1cc(C(=O)NC2CCN(C)CC2OC)c(C)cc1Nc1ncc(Cl)c(Oc2cccc3c2C(=O)N(C)C3)n1 +CCC(NC(=O)c1cc(C(=O)NC(CC)c2ccc(F)cc2)n2c1C(C)OCC2)c1ccccc1 +O=C(c1ccccc1)c1sc(NCc2cccs2)nc1-c1ccco1 +OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(C2Cc3ccccc3C2)CC1 +O=S1(=O)NCc2ccccc2N1C1CCN(C2CCCCCCC2)CC1 +NC1=NC2(CCO1)c1cc(NC(=O)c3ccc(Cl)cn3)ccc1Oc1c2cc(C2=CCCOC2)nc1F 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+O=C(NC(CNC(=O)c1ccc2nn(CCCNC3=NCCN3)cc2c1)C(=O)O)OCc1ccccc1 +Fc1cc(-c2nccnc2Oc2ccc(Nc3ccccn3)cc2)ccn1 +CSCCC(NC(=O)CNC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CCCc1ccc(-c2ccc(N(CC3(N)CCOCC3)C(=O)C3CC3c3ccccn3)cc2)cc1 +C=Cc1ccc(C(=O)NCCN2CCC(n3c(=O)[nH]c4ccccc43)CC2)cc1 +CC(Oc1cc(F)ccc1Nc1ncnc2cc(N=S3(=O)CCC3)cc(F)c12)C(=O)NC(C)C(F)(F)F +Cc1c(CN(C)c2ccccc2Cl)cnc2nc(N)nc(N)c12 +O=C(c1cc(-c2[nH]ncc2-c2cccc(Cl)c2)c[nH]1)N1CCOCC1 +Nc1nccc(-c2ccc3nc(C4COc5ccccc5C4)oc3c2)n1 +Cn1cc(F)cc(C2CCCN2c2ccn3ncc(C(=O)NC(CO)C(C)(C)C)c3n2)c1=O +COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2C)ccc1Cl +CN(C)N1C(CCc2ccccc2)CCCC1CCc1ccccc1 +CC1c2ncn(-c3ccc(F)cc3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1F +CON=C1CCC(CNc2cc(F)c(S(=O)(=O)Nc3nccs3)cc2Cl)CC1 +CCN(CC)CCNCCC(=O)Nc1ccc(Nc2nc(-c3ccccc3NC(=O)CCNCCN(CC)CC)nc3ccccc23)cc1 +CC(N)Cc1c2c(c(COCC(=O)Oc3ccccc3)c3c1OCC3)OCC2 +COC(=O)C1C2CCC(CC1c1ccc(C)c(F)c1)N2 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(CN3CCCC3=O)c12 +CC(C)CC(NC(=O)C(NC(=O)c1ccc(-c2ccccc2)cc1)C(C)O)B(O)O 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+CC1Cc2c(OCc3cc(-c4ccccc4)ccn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 +CC(=O)c1ccc2[nH]c(C(=O)N3CC4CC45C3=CC(=O)c3ccccc35)cc2c1 +CCCOc1ccc(C=CC(=O)Nc2ccc(NC(=O)Cc3ccc(C)cc3)c(C(=O)c3ccccc3)c2)cc1 +Fc1ccc2nc(-c3cccc(-c4cn5ccccc5n4)c3)[nH]c2c1 +O=C1CN(c2ccc(CO)cc2)CCN1CC(O)CN1CCc2ccccc2C1 +COc1ccc(CCNCC(O)COC(=O)c2cccc(F)c2)cc1OC +CCNC(=O)C1OC(n2cnc3c(N)nc(C#CCCCC#N)nc32)C(O)C1O +CC(C)CN(c1cccc(F)c1)S(=O)(=O)c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1 +COc1ccc2nc(NC(c3ccccc3O)P(=O)(OC)OC)sc2c1 +Cc1cccc(CC(NC(=O)c2ccc(F)cc2F)C(=O)NCC#N)c1 +CC1(C)CC(=O)c2c(SC(C)(C)C)sc(-c3cc[nH]n3)c2C1 +CCCC(C)=CC1CC2C=CC(C)C(CCC3CC(O)CC(=O)O3)C2C(OC(=O)C(C)(C)CC)C1 +Cc1ccc(C(=O)NN2C(=O)C(=Cc3cccn3C)SC2=S)cc1 +O=C(NN=C(c1ccccc1)c1ccccc1)Nc1ccncc1 +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc(CN4CCOCC4)c4onc(N)c34)cc2)c1 +O=C(O)c1nc(Cc2cc(Cl)ccc2OCc2ccccc2)cs1 +CS(=O)(=O)c1ccc2ccn(C3OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C3O)c(=O)c2c1 +COc1ccc(Nc2ncnc3ccc4nc(C(N)=O)sc4c23)cc1 +COCCOc1cc2ncnc(Nc3ccc(F)c(C#N)c3)c2c2c1OCCO2 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+CCOC(=O)c1c(-c2cccc(-c3ccccc3)c2)[nH]c2cc(OC)ccc2c1=O +CNCc1cc(C#CCCN2CCSCC2)ccc1Oc1ccc(Cl)c(Cl)c1 +NC(=O)c1cccc2c(NC(CCO)c3cccc(NC(=O)C4CC4(F)F)c3)ncnc12 +NCC1CCCCN1C(=O)C1CCC2CN1C(=O)N2OS(=O)(=O)O +O=C(NCc1ccc(OC(F)(F)F)cc1)C1c2cccc(F)c2C(=O)N1CCc1ccccn1 +CCCCCCCCCCCCCCCCCC(=O)c1n[nH]c2c1C(=O)N(c1ccc(Cl)cc1)C2=O +CCc1cccc(Nc2cc(NC3CCCCC3N)nnc2C(N)=O)n1 +CC(=O)OC1C=CC(=O)OC1C(COC(=O)C=Cc1ccccc1)OC(C)=O +C=CS(=O)(=O)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +Cc1cc(CN(C)C)ccc1C(=O)Cn1ccc(OCc2ccc(Cl)cn2)cc1=O +Cc1nc(N)nc(-c2c(Nc3cc[nH]n3)nc3ccc(-c4cncn4C)cn23)n1 +CC(NC1CCCNC1)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)CC2NCCc3ccccc32)CC1 +CN(C)c1ccccc1C(=O)N1CCN(C(=O)C(=O)c2c[nH]c3ccccc23)CC1 +COC12CCC3(CC1CNC(=O)C(CC(C)C)NC(C)=O)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +O=C(c1nnc(C2CCN(Cc3ccc(F)cc3)CC2)o1)c1nc2ccc(-c3ccccc3)cc2s1 +CC(C)N(C)CC#CCCC(=O)C(O)(c1ccccc1)C1CCCCC1 +COc1ccc(C(=O)Nc2ncc(-c3ccc(C(=O)O)cc3OCc3ccccc3Cl)s2)cc1 +CC1=C(C(=O)OC2CCCC2)C(c2ccc(Cl)cc2)C2=C(CC(c3ccc(Cl)cc3)CC2=O)N1 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+N=C(N)NCCCC(NC(=O)C1CCCN1C(=O)C(CC1CCCCC1)NCC(=O)O)C(=O)c1nc2ccccc2s1 +CC1CC(Nc2n[nH]c3cc(NC(=O)NC(C)c4ccccc4)ncc23)C(C)O1 +CCNC(=O)C1OC(n2cnc3c(Nc4ccc(OCC(=O)Nc5ccc6c(c5)OCO6)cc4)ncnc32)C(O)C1O +CC1(C)CC(=O)c2c(NCCO)sc(-c3cc[nH]n3)c2C1 +CC(C)c1[nH]c(=O)c(-c2csc(-c3ccncc3)n2)cc1C(=O)OCCN1CCCC1 +CN(c1ccc([N+](=O)[O-])cc1OCc1ccc([N+](=O)[O-])cc1)S(C)(=O)=O +ClC(Cn1ncc2c(Nc3ccccc3)nc(SCCN3CCOCC3)nc21)c1ccccc1 +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)NCCCCCO)ccc3OCC)nc12 +O=C(NC1CC(C(=O)O)Nc2cc(Cl)cc(Cl)c21)C1CCCCC1 +CCOC(=O)c1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 +CCN(C(=O)c1ccc(CNc2nc(NCCN(C)C)nc(N3CCc4ccccc4C3)n2)cc1)c1cccc(C)c1 +NC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2C(F)(F)F)cc1 +Oc1ccc2c(c1)CCC1CC(O)(C#CCl)CCC21Cc1ccccc1 +O=C(O)Cc1nn(CC(=O)Nc2cc(C(F)(F)F)ccc2Br)c(=O)c2ccccc12 +CN(C)CCn1c(=O)c2ccc3sc4ccccc4c4ccc(c1=O)c2c34 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NCC2CCOC2)cc1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=CC(=O)OC(C)(C)C)cc2)C(=O)c2ccccc2)c1 +CNCCCC1Cc2ccccc2N(c2c(F)cccc2F)S1(=O)=O +Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(Oc4ccccc4)cc3)(C(F)(F)F)C2)cc1 +O=C(O)CCNc1nc(Cc2nnc(SCC(=O)NNC(=O)c3ccccc3)n2NC(=O)c2ccc(Cl)cc2)cs1 +Cc1c(C)c2c(c(Cc3cn(CCCCCC4CCSS4)nn3)c1O)CCC(C)(C)O2 +COc1cccc2cc(C(=O)NCCCN3CCN(CCCNC(=O)c4cc5cccc(OC)c5oc4=N)CC3)c(=N)oc12 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccc2cc[nH]c2c1 +COc1ccc2c(c1)-n1ncc(C(=O)OCc3ccccc3)c1NC2 +O=S(=O)(Nc1ncns1)N1CCc2c(cccc2-c2ccc(C(F)(F)F)cc2C2=CCNCC2)C1 +COc1ccc2ncc(F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCc3cccc(N)c3)[nH]c3ccc(Cl)cc23)c1 +Cc1cc(OCCCCOc2ccc(C(=O)CC(C)C)c(O)c2C)ccc1C(=O)O +Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+](=O)[O-] +O=C1CC(O)CC(CCn2c(-c3ccc(F)cc3)ccc2C(F)(F)F)O1 +COc1ccc(CP(=O)(O)CC(CCC(=O)O)C(=O)O)cc1 +COc1cc(-c2cccc(C)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ncccn3)ccc21 +COc1cc(-c2cc(F)cc(Cl)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3cnccn3)ccc21 +COc1cc(Nc2ncc(C(O)c3ccc(Cl)cc3)s2)ccc1-n1cnc(C)c1 +CC12CCNC(=O)C=C1CCC1C2CCC2(C)C(O)CCC12 +O=C(O)Cn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccc(CNCCCc4ccccc4)c3)cc21 +CCc1ccc(CNCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(=O)NC(C)(C)C)c(C)c1 +N=c1n(CC(=O)NN=Cc2ccc(F)cc2)c2ccc([N+](=O)[O-])cc2n1CC(=O)NN=Cc1ccc(F)cc1 +Cc1cc(NC(=O)N2CC=C(c3ncc(-c4nnc(CO)o4)cc3Cl)CC2)ccc1OC(F)(F)F +CN(C)CCCNC(=O)c1cc(-c2c(O)cc(O)cc2Oc2ccc([N+](=O)[O-])cc2)on1 +Cc1nc2ccccc2n1-c1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +COc1cc(-n2ccnc2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)C)n1)CCN2 +C=CCC1Oc2ccc(OCC#N)c(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +O=C(O)CC1CCC(c2ccc(-c3ccc4c(c3)OCCN4C(=O)NCc3ccccc3)cc2)CC1 +CC(Cc1ccc(C#Cc2ccc(OC3CC3)cc2)cc1)NC(=O)C1CC1 +OCC1CC(Nc2nc(NC3CC3)ncc2-c2nc3cnccc3s2)C(O)C1O +COCCNc1nccc(-c2noc3c(F)c4c(cc23)CC2(C(=O)NC(=O)NC2=O)C2C(C)OC(C)CN42)n1 +Cc1ccc(COc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)cc1C +O=C(O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cccc21 +CC(C)(C)C(=O)Nc1ccc2ccn(Cc3cccc(-c4cccc5c4OCO5)c3)c2c1 +CCn1c(C(C)NS(=O)(=O)c2ccc(Cl)cc2)nc2ccccc21 +COc1ccccc1-c1nnc2c3c(c(OCc4ccccn4)nn12)C1CCC3CC1 +COC1CCC2(CC1)Cc1ccc(-c3cncc(C#N)c3)cc1C21N=C(N)N(C(C)C)C1=O +CCCCC(Sc1cc(OCCc2ccccc2)cc(OCCc2ccccc2)c1)C(=O)O +CC(C)S(=O)(=O)N1CCC(c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)CC1 +CCCCOC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1 +CC=C1C(C2(C)CCCC(C)(C)C2)=CCC2C(OC(C)=O)OC(OC(C)=O)C12 +COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1cccc(C)c1 +C=CCc1c(C)nc(-c2ccsc2)nc1Nc1ccc(C(=O)O)cc1 +CC(C)(C)CC1NC(C(=O)Nc2ccc(OCCO)cc2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-c2cncs2)c1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2cc(OCCO)ccc12 +CC(=O)c1ccc(Cn2nc3c(c2Nc2ccc(F)c(C)c2)C(=O)N(C)C2=NC(C)(C)CN23)cc1 +O=Cc1cn(-c2nc(-c3cc4cc(Br)cc(Br)c4oc3=O)cs2)nc1-c1ccccc1 +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)C(CN2CCOC2=O)CN1 +CNC(=O)c1cc2ccc(CCNC(=O)Nc3cccc(S(=O)(=O)C(F)(F)F)c3)cc2cn1 +CCOc1ccccc1-c1ccc(C(=O)NC(C=Cc2ccccc2)C(Cc2cccc(C(=N)N)c2)C(=O)OC)cc1 +COc1ccccc1-c1noc(C(C)Nc2nccc(N3C(=O)OCC3C(C)C)n2)n1 +O=C(NO)c1ccc(OCCCCCCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1O +COc1ccc(C=C2COc3cc(OCCCCCNc4c5c(nc6ccccc46)CCCC5)ccc3C2=O)cc1 +CC1(c2noc(NC3CCC(CNS(=O)(=O)C(C)(C)C)CC3)n2)CC(F)(F)C1 +COc1cc(Nc2cc(-c3ccccc3)on2)ccc1-c1cnco1 +NC1CN(c2ccncc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)CCC1F +COC(=O)CC1c2ccccc2N=C(Nc2ccc(-c3ccccc3)cc2)N1CCCCCNC(=O)OC(C)(C)C +CCN(CC)CCCNc1c(Cl)cccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +Cc1cccc(Cl)c1NC(=O)c1sc(NC(=O)c2cccs2)nc1C +Cc1cc(=O)oc2cc(OCC=CCN3CCC(c4noc5cc(F)ccc45)CC3)ccc12 +O=C(O)c1cc(-c2ccc(C=C3SC(=S)N(CCc4ccccc4)C3=O)o2)cnc1Cl +O=C(c1cccc(Nc2ncc(-c3ccc4c(c3)OCO4)cn2)c1)N1CCOCC1 +CC(C)CS(=O)(=O)NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1 +COc1cc(-c2c(-c3ccc4[nH]ccc4c3)c(=O)c2=O)cc(OC)c1OC +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc4c(c3)OC(F)(F)O4)C2)cc1 +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1Br)c1cccc(C(=N)N)c1 +O=C1Cc2cc(Cc3ccc(-c4cccs4)cc3)ccc2C(=O)N1O +[O-][n+]1ccc(CC(c2ccc(COc3ccc(F)cc3)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 +CCNc1cc(O)c2c(c1)C=CCC(OC(=O)C(F)(F)F)C(O)C(=O)C=CC(C)C(C)OC2=O +COc1ccc(-c2ccc(C(N)=O)nc2)cc1OC1CC2CCC1C2 +CC(C)n1c(=O)n(Cc2nc3ccccc3n2CCN(C)C)c2ccccc21 +O=C(Cn1c(-c2ccccc2)nc2ccccc21)Nc1ccc(Cl)cc1 +COc1ccc(-c2cc(C(=O)NC3CCCc4c3cnn4-c3ccccc3F)n(C)n2)cc1 +CCCC(CC1(C(=O)NC(CO)Cc2ccccc2)CCCC1)C(=O)O +COc1ccc(CNC(C)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +CCS(=O)(=O)n1cc(C(=O)OC2CC3COCC(C2)N3)c2ccccc21 +CCc1c(C#N)c(-c2ccc(-c3cccc(OC)c3)cc2)c(C(=O)O)n1C +Cc1cc(F)ccc1Nc1nc2cc(F)c(N(C)C(=O)C=CCN(C)C)cc2n2cncc12 +O=C(NC1CCC(CCN2CCC(c3noc4cc(F)ccc34)CC2)CC1)c1ccc(N2CCOCC2)nn1 +CN(C)C(=O)c1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 +Cc1cc(Nc2cc(N3CCCCC3)nc(Sc3ccc(NC(=O)C4CCCCC4)cc3)n2)n[nH]1 +O=C(O)c1cccc(-c2cnc(C(=O)C3Cc4ccc(-c5ccccc5)cc4C3)o2)n1 +COc1ccc(S(=O)(=O)N(Cc2ccc(F)nc2)C(C(=O)NO)C(C)C)cc1 +CC1(C)CC(n2ncc(NCCN3CCOCC3)c(Cl)c2=O)CC(C)(C)C1 +CN1Cc2c(C3=CCN(C4CCC(CC(=O)O)CC4)CC3)[nH]c3nccc(c23)-c2cc(F)c(F)cc21 +O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)F)c3)s2)nn1 +Cc1ncn(-c2ccc(Nc3cc(-c4nocc4C)ccn3)cc2)n1 +COc1ccc(-c2cnn(-c3ccc(S(=O)(=O)Nc4ccc(CCNCC(O)c5cccnc5)cc4)cc3)n2)cc1F +CCC(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CC1CCCCC1)NC(=O)N1CCOCC1 +COc1ccc(C(=O)NCc2cccc(Oc3ccc(OC(C)(C)C(=O)O)c(C)c3)c2)c(C)c1 +CC1CCN(C(=O)c2cccc(COc3c(Cl)cccc3Cl)n2)CC1 +CN(C)CCOCCn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)N(CCN(C)C)C3=O +N=C(N)c1cccc(CN2CCC(NS(=O)(=O)c3cc4nc(Cl)ccc4s3)C2=O)c1 +CC(C)C(NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)C(=O)NO +Cc1ccc(CNC(=O)Nc2cccc3[nH]ncc23)c(N2CCCCC2)n1 +CCNC(=O)c1cc(N)c(Nc2ccc(C#N)cc2)cc1Oc1c(C)cc(CCC#N)cc1C +ON=C(CCCN1CCN(c2ccccn2)CC1)c1ccc(F)cc1 +NC(=O)c1ccccc1-c1cc(F)cc(-n2nnc(-c3ccccn3)n2)c1 +C=CCN1CC(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)OC1=O +CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCN +O=C1C2=C(OC3=CC=CCC13)C([N+](=O)[O-])=CCC2 +CC(C)S(=O)(=O)NCC1CC(c2ccc(-c3ccccc3C#N)c(F)c2)=NO1 +NS(=O)(=O)c1c(F)c(F)c(Sc2nc3ccccc3s2)c(F)c1F +CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(=O)O)c1 +CC(c1ccc(F)c(F)c1)N1CCC2(CCC(O)CC2)OC1=O +COC1CN(C(=O)N2CCC(C)(N3CCc4c(-c5cnc(N)nc5)nc(N5CCOCC5C)nc43)C2)C1 +OCC(CN1CCN(Cc2ccccc2)CC1)OC(c1ccccc1)c1ccccc1 +COc1cc(-c2ccc3c(-c4nc5ccccc5[nH]4)n[nH]c3c2)c(CO)cc1O +NC(C(=O)O)C(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)O +O=C(O)c1cccc(Nc2cccc(S(F)(F)(F)(F)F)c2)c1 +COC12CCC3(CC1(C)C(O)c1cccc(F)c1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CC(O)(c1ccc(N(C(CF)CF)S(=O)(=O)c2ccccc2Cl)cc1)C(F)(F)F +O=C(NCc1ccccc1)OC1COC2C(OC(=O)c3cccc4ccccc34)COC12 +CC(C)(CO)NC(=O)c1cc2cc(Nc3ncc(F)c(Nc4cccc(O)c4)n3)ccc2o1 +c1cc2occc2c(NC2=NCC3(CN4CCC3CC4)O2)n1 +CCc1cc2c(cc1N1CCC(N3CCN(C)CC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(-c4cnc5ccccc5n4)cc32)c1C +COc1ccc(Nc2nc(-c3ccc(C(N)=O)c(F)c3)cn3ccnc23)cc1OC +Cn1c(=O)c2nc(-c3ccccc3N)[nH]c2n(C)c1=O +CN1C(=O)C(N2CCc3cn(Cc4c(F)cccc4F)nc3C2=O)COc2cc(C#N)ccc21 +c1cc(C2CNCCO2)ccc1Nc1ncc(C2CC2)cn1 +CN(c1ccc(Cl)cc1)c1ccc(C(=O)c2ccc(C(=O)C3CC3c3ccccc3)c(C(=O)O)c2)nc1 +Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccccc2)C(N)C3)c1 +CC(C)c1ncc(CO)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +Cc1nnc(Nc2nc(N3CCN(C(=O)Cc4ccccc4)CC3)nn3cccc23)s1 +CC(=O)Nc1cccc(Cl)c1C(=O)OCN1C(=O)c2ccccc2S1(=O)=O +Cc1cccc([P+](Cc2ccc(Oc3ccccc3)cc2)(c2cccc(C)c2)c2cccc(C)c2)c1 +COCCOC1CCC2(CC1)Cc1ccc(Cl)cc1C21N=C(N)N(C)C1=O +FC1CCNCC1n1cc(-c2ccc3c(c2)Cc2c[nH]nc2-3)c(-c2ccncc2)n1 +CCOC(=O)c1cn(C)c(=O)cc1Nc1ccc(I)cc1F +O=S(=O)(c1ccc(Cl)cc1)C12CCOC(CCC(O)CO)C1COc1c(F)ccc(F)c12 +O=C(c1ccc2c(c1)-c1[nH]nc(-c3ccc(-c4ccc(O)cc4)cc3)c1C2)N1CCOCC1 +CC(C)CCNc1ccc2nnn3c4ccccc4c(=O)c1c23 +NC1(c2ccc(-c3nc4ccn5c(=O)[nH]nc5c4cc3-c3ccccc3)cc2)CCC1 +O=C(Nc1nnc(-c2cncs2)s1)C(Cc1ccccc1)NCc1cscn1 +Brc1c(Br)c(Br)c2[nH]c(NCCCn3ccnc3)nc2c1Br +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4nccs4)o3)cc2Cl)CS1(=O)=O +COc1cc(-c2ccc(F)cc2F)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CS(=O)(=O)c1ccc(Nc2nccc(Oc3ccc4c(C(=O)Nc5ccccc5)cccc4c3)n2)cc1 +COc1ccc(-c2cc3c(NC4CCC(C)(N)C4(C)C)c(C(N)=O)cnn3c2)cc1 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+C=CC(=O)Nc1ccc(CNc2nc(Nc3cnn(CCOC)c3)ncc2Cl)cc1 +O=C(NCCc1nc2ccccc2[nH]1)c1ccc(Cl)c([N+](=O)[O-])c1 +CC1CCC(NC(=O)c2cc3cc(Br)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 +CC(O)(C(=O)Nc1ccc(S(=O)(=O)NCCc2ccc(F)cc2)cc1Cl)C(F)(F)F +NC(=O)c1cncc(OCc2cccc(NC(=O)c3cc4ccccc4[nH]3)c2)c1 +O=C(NCC1CCC1)c1ncccc1NC(=O)c1cccc2cccnc12 +NCc1ccn2c(-c3ccnc(N)n3)c(-c3ccc(F)cc3)nc2c1 +COc1nc2cccnc2n1-c1ccc(C(=O)c2nc3ccccc3[nH]2)cc1 +Cc1ccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)s1 +CCNC(=O)C(CCc1ccccc1)NC(=O)C(NC(=O)c1ccc(OCc2ccccc2)cc1)C(C)O +CCCCN1CCN(c2ccc(S(=O)(=O)Oc3cccc(F)c3)cc2)C1=O +CC(C)CC(CC(=O)NO)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)NC(C)c1ccccc1 +COc1ccc(NC(=O)Nc2ccc(N(C)C)cc2)cc1-c1c(Br)cnn1C +O=C(O)c1ccc(-n2c(C=Cc3cccc([N+](=O)[O-])c3)nc3ccc(I)cc3c2=O)cc1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2cccc(Cl)c2)CCN(C(=O)OC(C)(C)C)CC1 +O=C(NCC1(O)CCCCCC1)c1cc(-n2ncc(=O)[nH]c2=O)ccc1Cl +COc1ccc(OC)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc3c(c2)sc(=O)n3C)c1 +NC(=O)c1ccc(Oc2ccc3c(c2)CN(CCc2ccccc2)C3)nc1 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+CC(C)Oc1ccc2cc(-c3nn(C(C)C)c4ncnc(N)c34)ccc2c1 +O=c1cc(C(F)(F)F)c2cc3c(cc2[nH]1)OCC1CCCCN31 +O=C(Nc1ccc(Br)cc1)C1C(C(=O)NC2CCC(CN3CCCC3)CC2)C2C=CC1C21CC1 +O=C(O)Cc1csc(-c2cc(Cl)ccc2OCc2ccccc2)n1 +O=C1C(O)c2ccccc2N1CCn1cc(COc2ccc(CNNc3ccnc4cc(Cl)ccc34)cc2)nn1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cccc(C(N)=O)c3)NC(=O)NC1=O)C2 +CC1(C)C(C(=O)O)C1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(-c2ccc(F)cc2)c1 +COCC1OC(OCCc2ccccc2)C(NCCN)C(OCc2ccc3ccccc3c2)C1O +c1ccc(-c2nnn(-c3ccc(Oc4cccnc4)cc3)n2)nc1 +CCSC(=S)SCC(=O)c1ccc(C(=O)NCc2ccccc2)s1 +Cc1ccc(C2CC3CCC(C2c2cc(-c4ccc(F)cc4)no2)N3C)cc1 +COc1cc(C=CC(=O)NO)ccc1OCC(Cc1c[nH]c2ccccc12)NC(=O)C1CCCN1C(=O)OC(C)(C)C +CN(C)C(=O)c1ccccc1Sc1cc(N)c(Cl)cc1[N+](=O)[O-] +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)NC(C)(C)C)CC1 +COC1(C)CC(O)C2C(C)C(=O)OC2C2C1CCC2(C)O +O=C(Nc1ccc(Cl)cc1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCc1cc(Cl)ccc1-2 +FC(F)(F)c1ccc(Nc2nccc3nc(-c4ncccc4C(F)(F)F)cnc23)nc1 +COCC(C)NC1CCC(Nc2cc(-c3ccc(F)c(NCC4CCOCC4)n3)c(Cl)cn2)CC1 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+CCN1Cc2n[nH]c(=O)c3cc(F)cc4[nH]c(c2c43)C1 +Cc1ccc(OC(=O)NC2CC(C)CCC2C(C)C)cc1 +CN1C(=O)C=CC2(C)C3CCC4(C)C(CCC45CCCO5)C3CCC12 +CC1(C(=O)O)CCC(O)(c2ncc(-c3cccc(Nc4nccc(C(F)(F)F)n4)c3)s2)CC1 +O=C(NCC1CCCCC1)c1cnc(Nc2cccc(Cl)c2)cc1C(F)(F)F +COc1ccc(CSc2nnc(-c3ccc4c(c3)CCO4)o2)cc1Cl +N#CNC(=NCCCCCCOc1ccc(Cl)cc1)Nc1ccncc1 +CCN(CC)CCOC(=O)C1(c2ccc(-n3cnnn3)cc2)CCCC1 +OC(CCCN1CCN(c2ncc(F)cn2)CC1)C1CCCCC1 +O=C(CC(=O)N1CCOCC1)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 +O=C(N1CCc2ncc(C(F)(F)F)cc2C1)C12CCCC1CC(NC1CCCCCC1)C2 +CC(=O)c1ccc(Oc2ncnc3c2cnn3C2CCN(C(=O)OC(C)(C)C)CC2)cc1 +COc1cc(OC)c2nc(C(F)F)n(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)c2c1 +CNc1ccc(-c2noc(C(CCCC3CCCCC3)CC(=O)NO)n2)cn1 +O=C(c1c[nH]c2cc(Cl)ccc12)N1CCC2(CC1)c1ccccc1CS2(=O)=O +Nc1nc(N)c2cc(NCc3cccc4ccccc34)ccc2n1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC2Cc3ccccc3C2)C1c1cccc([N+](=O)[O-])c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1cnc(Oc2ccc(F)cc2)cn1 +CC(OC1CCCNC1c1ccccc1)c1cc(Cl)cc(Cl)c1 +CC1=C(CCCN)C2=C(C)C3(CC3)C(C)(O)C(=O)C2=C1 +COc1cccc2c1cc(CCNC(=O)C1CC1)n2-c1ccccc1 +CC(c1nc2ccccc2c(=O)n1-c1ccc(Br)cc1)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)C(C)C1 +COC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccccc3Cl)C2)C1c1ccc([N+](=O)[O-])cc1 +Cc1cc(C)nc(N2CC3CCN(C(=O)c4cccc(C)c4-n4ccnn4)CC32)n1 +CCn1c(CN2C(=O)COc3cc(OC4CCN(C(C)=N)CC4)ccc32)cc2ccc(C(=N)N)cc21 +CN1CCC(O)(C#Cc2ccc3c(c2)-n2nc(C(N)=O)c(C(F)F)c2CCO3)C1=O +NNC(=O)CSc1nc2ccccc2c(=O)n1CCc1ccccn1 +CC(C)(CN(CC(=O)NC(CCCCN)B(O)O)C(=O)CCc1ccccc1)c1ccccc1 +FC(F)(F)c1ccnc(Sc2ccc3nnc(-c4cncs4)n3n2)n1 +CCN(CCCOc1cc(O)c2c(=O)c3ccccc3sc2c1)Cc1ccccc1N(C)C +CNC(=O)c1cnc(N)c2cc(-c3ccc(C)cc3)sc12 +N#Cc1ccc(Cn2cncc2CNC2C(=O)N(c3ccccc3)CCc3ccccc32)cc1 +Cn1nc(-c2ccc3c(c2)CC2CCC(C3)C23CN(CC(F)(F)F)S(=O)(=O)N3)cc1-c1ccc(Cl)c(Cl)c1 +CCOC(=O)C1CCN(C(=O)CCC(=O)N(CC(C)(C)C)c2ccc(Cl)cc2C(O)c2ccccc2Cl)CC1 +O=C(NO)c1ccc(CN2C(=O)CNC(=O)C2Cc2cccs2)cc1 +CCCCC(=O)c1cc(C(C)(C)C)c2c(c1)C(C)(C)CO2 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3c[nH]c4ccncc34)nc21 +CCc1cc(C2CC2)c(-c2nnc(OC)[nH]2)cc1C(=O)N1CCC(F)(c2ccc(C#N)cc2)CC1 +Cc1c(C)c2ccc(OCc3c(F)c(F)c(F)c(F)c3F)cc2oc1=O +COc1cccc(C(=O)NN2c3ccc(Cl)cc3N=C(N3CCN(C)CC3)c3ccccc32)c1 +CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3ccc4c(n3)C(=O)N(Cc3ccc(F)cc3)CC4)cc12 +COc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3cc(Cl)ccc32)ccc1OCCN1C(=O)CSC1=O +CN1CCC2(CC1)NC(=O)c1cc(C=CC(=O)NO)ccc1O2 +COC1CCN(C(=O)C(C)Oc2cc(F)ccc2Nc2ncnc3cc(N=S(C)(C)=O)cc(C)c23)CC1 +CCCCON=C1C(=O)N2c3ccccc3C34CCN5CC6=CCOC1C(C6CC53)C24 +CCOC(=O)C1CN(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CCO1 +Cc1ccc(CC2(O)CCN(CCOc3ccc(O)cc3)CC2)cc1 +O=C(CCN1CCN(c2ncccn2)CC1)NC12CC3CC(CC(C3)C1)C2 +CCC1(C(=O)Nc2cc(N(C)C)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)C1C +O=C(Nc1ccc(N2CCOCC2)cc1)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 +Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl +O=C(NC1CCN(C2CCc3cc4c(cc32)OCO4)CC1)c1cc(=O)c2cc(F)ccc2o1 +Cn1cc(-c2cc(NS(C)(=O)=O)ccc2OCc2ccccc2)c2cc[nH]c2c1=O +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(Cl)cn3)c2)c2cnccc21 +COc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cc(F)cc34)c2)cc1F +Cc1nc2ccc(CN(C)c3ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(N)c3)cc2c(=O)[nH]1 +CC(C)c1noc(-c2ncn3c2CN(C)C(=O)c2ccccc2-3)n1 +CCOc1ccc(C2=C(c3ccccc3)CCCc3cc(O)ccc32)cc1 +Cc1c(-c2ccc(C(C)N3CCC(CC(C)(C)O)(c4ccccc4)OC3=O)cc2)cc(=O)n(C)c1C +COCCOc1cc(OCCOC)cc(C(=O)NCCOC(=O)C2CCCCN2S(=O)(=O)Cc2ccccc2)c1 +COc1ccc2c(c1)Oc1ncn3nc(CC#N)nc3c1C2c1ccc(Cl)cc1 +Nc1nc2[nH]c(CCCc3ccc(C(=O)O)s3)cc2c(=O)[nH]1 +O=C(CCc1ccccc1)N(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)C1CCCCC1 +NS(=O)(=O)Oc1ccc(NC(=O)N2CCN(c3nccc(-c4cc5ccccc5o4)n3)CC2)cc1 +CN1CCN(C(=O)c2cc(Oc3ccc(Cl)cc3)c3c(c2)c2ccccc2n3CCCN2CCCCC2)CC1 +NCc1ccc(C(=O)Nc2ccncc2F)cc1-c1cccc(C(=O)OC2CCCOC2)c1 +COc1ccc(CC(=O)NC(NC(=NC#N)Nc2cccnc2OC)C(C)(Cl)Cl)cc1OC +Cc1cn(-c2ccc(-c3nc(Nc4cc(C(F)(F)F)ccc4F)n(C)n3)cc2OC(F)(F)F)cn1 +COc1ccc(C=CC(=O)C=Cc2ccc(OC)cc2)cc1 +CCCCCCCCCCCCCCCCN1C(=O)C(=O)c2ccccc21 +Cc1noc(C)c1CN(Cc1ccc2nc(C)n(C)c(=O)c2c1)c1ccc(C(=O)NCc2cccnc2)cc1 +N#CCc1ccc(Nc2ncnc3ccc(-c4cccc([N+](=O)[O-])c4)cc23)cc1 +C=Cc1csc(Sc2cc3c(cc2NS(C)(=O)=O)COC3=O)n1 +CC(Nc1c(Nc2ccnc(Nc3ccc(Br)cc3)n2)c(=O)c1=O)C(C)(C)C +CS(=O)(=O)NC1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 +O=C(NCc1ccc[nH]1)C(=O)c1c[nH]c2ccccc12 +NCC1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1 +CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(CCC(=O)O)CCC43O)C2)C(O)C(O)C1O +COc1ccc(-c2cccc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)n2)cc1 +COC(=O)C(CCSC)NC(=O)c1cccc(CN(Cc2ccc(C#N)cc2)Cc2cncn2Cc2ccc(C#N)cc2)c1 +Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)N1CCNCC1 +Cc1nccn1CCC(C(N)=O)(c1ccccc1)C1CCCCC1 +COc1ccc(C(=O)Nc2ncccn2)cc1Nc1nccc(-c2cccnc2)n1 +CCc1ccn2c(C3CCN(CC4CN(C(CC5CCC5)C(=O)O)CC4c4cccc(F)c4)CC3)cnc2c1 +COCCOc1cc2c(cc1C(=O)Nc1ccc(F)c(Cl)c1)nc(Nc1c(Cl)ccc(CNC(=O)C(C)(C)C)c1Cl)n2C +O=C1NC(=O)C(c2ccc(Oc3ccccc3)cc2)(N2CCCN(C(=O)c3c(Cl)cccc3Cl)CC2)C(=O)N1 +CCCCCOc1cc2ccccc2cc1C(O)CCCCCCC(=O)O +COC(=O)CCc1cccc(-c2nc(NCCc3ccc(F)cc3)nc(OC)n2)c1 +COC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccc(N)c(NC(=O)C(N)CCCNC(=N)N)c1 +CNC(=O)n1cc(NC(=O)N2C(C(=O)NC(CN(C)C)c3cccc(Cl)c3F)CC3CC32)c2ccccc21 +Cc1cnccc1-c1[nH]c(-c2ccc(Cl)cc2)nc1-c1ccc(F)cc1 +OC(COc1ccnc2cc(C(F)(F)F)ccc12)CN1CCN(C(c2ccccc2)c2ccccc2)CC1 +O=C(O)c1nc(-c2ccccc2)n(-c2cccc(Cl)c2)c1-c1cccc(Cl)c1 +Cc1c(Cc2c(Cl)cccc2Cl)c(=O)ccn1CCc1ccc(-c2c[nH]c(CNC(=O)Nc3ncc(Br)s3)n2)cc1 +Cn1cc2c(nc(N=C(Nc3ccc(Br)cc3)Nc3ccc(Br)cc3)n3nc(-c4ccco4)nc23)n1 +COc1ccccc1N1CCN(CCCOC(=O)CC23CC4CC(CC(C)(C4)C2)C3)CC1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(CF)(CF)Oc4ccccc43)cc21 +COc1ccc(S(=O)(=O)c2nc3ccccc3nc2Nc2ccccc2)cc1 +CC(=O)Nc1cccc(Nc2ncnc(N3CCC(c4ccccc4)CC3)n2)c1C +Cn1cc(-c2ccc3nc(NC(=O)c4csc(-c5ccncc5)n4)cn3n2)c(-c2ccc(F)cc2)n1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1Nc1cnn(CC(F)(F)F)c1 +Cn1cc(C2=C(c3c[nH]c4cc(F)ccc34)C(=O)NC2=O)c2ccccc21 +COCCNC(=O)c1c(NC(=O)c2ccccc2OC(F)(F)F)sc2c1CCC(F)(F)C2 +CC(=O)Nc1ccc(OC2OC(CO)C(O)C(O)C2O)cc1 +CN(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1cccc(-c2ccccc2)c1 +CC1CC(O)(CC(=O)O)c2cc(Cl)c(OCc3ccccc3)cc2O1 +Cc1cnc(Nc2ccc(CN3CCN(C)CC3)cc2)nc1-c1cccc(Cl)c1 +NC(=O)Nc1cccc(-c2cnc3cc(-c4nncs4)ccn23)c1 +O=C(Cc1cccc(Br)c1)Nc1ccc(O)c(-c2cc(C(=O)O)ccn2)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CC(C)C)ncc3Cl)C2)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCCN5CCC(F)(F)CC5)s4)nc23)N1 +CN1CCN(c2cccc(C(=O)c3cnn(-c4ccc(F)cc4)c3N)c2)CC1 +CC(C)(C)C1CCc2onc(C(=O)Nc3cnn(Cc4ccc(Cl)cc4)c3)c2C1 +Clc1ccc2c(c1)c(NC1CCN(Cc3ccc4c(c3)OCO4)CC1)nn2-c1ccccc1 +CN(Cc1ccc(Br)cc1)c1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +CN1CC(COc2ccc(S(=O)(=O)Nc3cccc(CC(=O)O)c3)cc2)Oc2ccccc21 +Cc1nc(C(=O)NC2C3CC4CC(C3)CC2C4)c(C)n1-c1ccccc1 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cccc(-c5ccncc5)c4)c3)cc2C1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1cc(Cl)c(F)cc1-c1cn[nH]c1 +CCN(CC)c1ccc(C(=O)c2cc(C#N)c3ccc4ccccc4n23)cc1 +[O-][S+](c1cc(Cl)cc(Cl)c1)c1c(O)c(-c2cccnc2)cc2ccccc12 +COC(=O)COc1cc2c(c3c1c(C(=O)C(N)=O)c(C)n3Cc1ccccc1)CCC2 +Cn1cc2c(Nc3nc(NC4CCCCC4N)nnc3C(N)=O)cccc2n1 +O=C1c2ccc(C3CC3)cc2OCCN1c1cccc(-c2ccnc3[nH]c(-c4ccc(C(O)CO)cc4)cc23)c1CO +CCCCc1nc(-c2ccc(C(=O)OC)c[n+]2[O-])cn1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1ccc(C)c2c1Sc1c(ccc3ccccc13)N2CCCN(C)C +CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(CCC(c2ccccc2)c2ccc(C(N)=O)cc2)CC1 +Cc1cc(Nc2c(C)cccc2C)c2nc(N3CCOCC3)cc(=O)n2c1 +CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)cc(-c2ccc(Cl)cc2)c1F +CNCCN1CCC(c2cnc3[nH]c(-c4cccnc4OC)nc3c2)CC1 +CN1C2CCC1C(C(=O)OCCOS(=O)(=O)c1ccccc1)C(c1ccc(Br)cc1)C2 +CN(C)CC(=O)N1CCC2(CC1)C(=O)Nc1cc(C=C3c4ccccc4COc4cc(F)ccc43)ccc12 +CNC(=O)c1ccc(C)c(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)c1 +Cc1cc(Cl)nc(C)c1C(=O)NCCC(C)N1CCC(N2C(=O)N(C(C)C)CC2c2ccccc2)CC1 +Cc1cc(S(=O)(=O)NC(=O)Nc2ncc(Br)s2)sc1CC(C)C +O=C(NCc1c(Cl)cc(Cl)cc1Cl)C1COc2ncccc21 +CC(C)c1ccc(-n2cc(C(=O)c3ccc(N)cc3)nn2)cc1 +Clc1cccc(N2CCN(CCCCNc3cc(-c4ccccc4)ccn3)CC2)c1Cl +O=C(CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1)N1CCC1 +NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1Cl +NS(=O)(=O)c1ccc(N2C(=O)CSC2c2ccccc2Br)cc1 +Cn1c(=O)c2c(SCC(=O)NCc3ccccc3)ccnc2n(C)c1=O +Cn1cc(-c2cnc3[nH]cc(-c4cc(C5(c6ccccc6)CC5)nc(N)n4)c3c2)cn1 +CNc1cc(-c2cccnc2)ccc1S(=O)(=O)c1ccccc1 +CCCCc1nc2ccc(NC)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(-c2ccc(S(=O)(=O)c3ccccc3CC(=O)NO)cc2)cc1 +CN1CCN(C(=O)c2cc(Oc3ccc(Cl)cc3)c3c(c2)c2ccccc2n3CC2CCN(C3CC3)CC2F)CC1 +O=S(=O)(Nc1nccs1)c1ccc2c(c1)OCCC2Oc1ccc(C(F)(F)F)cc1C1=CCNCC1 +COc1cc(C2=CCCCc3c2ccc2c3c(CO)cn2C)cc(OC)c1OC +c1ccc(CC2CCN(CCCn3nnnc3-c3cccc4ccccc34)CC2)cc1 +Cc1cccc(C(=O)Nc2ccc(Cl)cc2)c1NC(=O)c1sc2ccccc2c1Cl +COc1ccc(-c2cnc3nc(N)nc(N4CCN(Cc5ccccc5F)CC4)c3n2)cc1OC +COc1ccc(Cl)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2ccc(OC(F)F)cc2o1 +CC(CC(C)(CS(=O)(=O)N1CCC(CCc2ccc(C(F)(F)F)cc2Cl)CC1)N(O)C=O)c1ncc(F)cn1 +COCCOCC(C)(C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 +COc1cccc(C2=CC(=O)c3ccc4c(c3=N2)=CC=N4)c1 +N#Cc1ccc(C(c2ccc(C#N)cc2)n2cncn2)cc1 +CCCCN(CCSC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)nn(C)c12 +CC#Cc1cncc(-c2ccc3c(c2)C2(COC(N)=N2)C2(CCC2)CO3)c1 +COC(=O)CCc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1 +NS(=O)(=O)Oc1ccc2c3c(c(=O)oc2c1)CCCCCCCCCCC3 +CCCOc1ccc(-n2cc(CCc3ccccc3)c3cc(CCC(=O)O)ccc32)cc1 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+Cn1cc(-c2cc3c(-c4cccc(N5CC6CC5CN6)n4)n[nH]c3cn2)cn1 +CNC(=O)C(NC(=O)C(CCc1ccccc1)CP(=O)(O)Cc1ccc(Cc2ccc(OC)cc2)cc1)C(C)(C)C +CN(Cc1cccc2c1S(=O)(=O)N=C2C1=C(O)C(C(C)(C)C)N(Cc2ccc(F)cc2)C1=O)S(N)(=O)=O +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc(C(=O)c3ccc(Cl)cc3)c2)[nH]c1=O +CCC(Nc1ncnc(N)c1C#Cc1cnccn1)c1nc2cccc(F)c2c(=O)n1-c1cc(F)cc(F)c1 +CCCc1[nH]c(=O)c(Cc2ccc3oc4ccccc4c3c2)c2cc(OC)c(OC)cc12 +CC1CCCC(N2CCC(c3c(-c4ccccc4)ccc(Cl)c3F)=CC2=O)c2cc(ccn2)-c2ccccc2NC1=O +CC(C)(C)OC(=O)n1cc(-c2cncn2C2CCCCC2)c2ccccc21 +CCC(=O)N(CCCCCCCCNC(=N)N)C1CCN(CCc2ccccc2)CC1 +CC(=O)c1cc(-c2c3c(=O)n(C)c(=O)n(CC4CC4)c3nn2Cc2ccnc3ccc(Cl)cc23)n(C)c1 +CC(=O)Nc1ccc(CCN(C)C2CCN(CCCc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)cc1 +COCC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)C(c2ccc(F)c(F)c2)NC(=O)N1 +CC(=O)NCC1CN(c2ccc3c(c2)CCCc2c(-c4cc(C)on4)n[nH]c2-3)C(=O)O1 +CCC1C(=O)N(C2CCN(C3CCC4CCCc5cccc3c54)CC2)c2ccccc21 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccc(C#N)cc2[nH]1)C(F)(F)F +O=C(CNC(=O)c1ccccc1)NN=Cc1ccc([N+](=O)[O-])s1 +O=C(NC1CCC(OCCCN2CCOCC2)CC1)NC12CC3CC(CC(C3)C1)C2 +CCNC(=O)C1OC(n2cnc3c(N)nc(C#CC(C)(O)CC(C)C)nc32)C(O)C1O +Cc1noc(C)c1-c1ccc2c(c1)C(O)(c1ccc(F)cc1)C(=O)N2 +N#Cc1ccc(-c2cnccc2NS(=O)(=O)C(F)(F)F)c2ccccc12 +c1ccc(-c2n[nH]c(C3CC3)c2-c2ccnc3ccccc23)nc1 +COc1cccc(C(=O)NC(CC(C)(C)C)C(=O)NC(CCS(C)(=O)=O)CN2CCc3cc(F)ccc32)c1 +O=C(Nc1ccccn1)c1cccc(Oc2ccc3c(c2)c(=O)ncn3Cc2c(F)cc(F)cc2F)c1C(F)(F)F +COC12C(COC(N)=O)C3=C(C(=O)C(C)=C(Nc4ccc5[nH]ccc5c4)C3=O)N1CC1NC12 +Cc1nnc(C(NC(=O)c2cc(OC(C)C(F)(F)F)c(C3CC3)cn2)C2(C)COC2)o1 +COc1cccc(CC2NCCc3c2[nH]c2ccccc32)c1 +S=C(NCCCc1cnc[nH]1)NCCCN(Cc1ccc(Cl)cc1)c1ccc(Br)cc1 +CCCn1c(=O)c2nn(-c3ccccc3)cc2c2ccccc21 +Oc1ccc2c(c1)CCCC2CCCN1CCN(C2CCCCC2)CC1 +CC(C)(C)OC(=O)N1CCN(c2ccc(C#Cc3ncnc(N)c3-c3ccc(Cl)cc3)cn2)CC1 +COc1cc(N(C)CCN(C)C)c2[nH]c(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1 +O=C(c1ccc(F)cc1)C1CCN(Cc2ccccc2I)CC1 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(Cc2ccccc2)C1 +Cc1ccccc1NC(=NC#N)N1CCN(C(=O)Cc2ccccc2)C(c2ccccc2)C1 +O=c1c2scc(-c3ccccc3)c2ncn1-c1ccc(F)cc1 +O=C(NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCN2CCOCC2)N1)c1ccc2cc(Cl)ccc2c1 +O=C(Cc1ccc(NC(=O)c2cscn2)nc1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=C(O)CCC(=O)NC(=Cc1ccc(Oc2ccccc2I)cc1)C(=O)O +COn1cc(C2=NC(c3ccc(F)cc3)(c3ccc(F)nc3)C(C)N2)ccc1=O +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)O)cc3)[nH]c2n(CCC)c1=S +Cc1nc2ccccc2c(N2CC(C)(C)c3ccc(N4CCOCC4)cc32)c1C +O=C1c2ccccc2C(=O)N1CCCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +O=C1c2cc(NCCN3CCOCC3)ccc2COc2cc(Oc3ccc(F)cc3F)ccc21 +CCC(C)N(Cc1nc2c(c(=O)[nH]1)COCC2)C(=O)CN1CCC(C(=O)c2ccc(F)cc2)CC1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O +Cc1ccc(S(=O)(=O)N=C(Sc2ccccc2)c2ccccc2)cc1 +COc1cnccc1C(=O)NCC(C)(C)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +CC1CCC(Cn2c(N3CCOCC3c3ccccc3)nc3cc(C(=O)N(C)C)nc(-c4cncc(Cl)c4)c32)CC1 +CC(=O)OC1CCC2C3C=CC4=CC(=O)C=CC4(C)C3CCC12C +NC(Cc1ccc(-c2cnc(NCC3CCc4ccccc4C3)cn2)cc1)C(=O)O +C=C(Br)C(=O)Nc1ccc2[nH]c(C(=O)NCCCNc3nsc4nc5ccccc5n34)cc2c1 +O=[N+]([O-])c1cccc(Nc2nccc(-c3cnn4ncccc34)n2)c1 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+O=C(COc1ccc(SCCCCSc2nccs2)cc1)COc1ccc(C(=O)O)cc1 +Cc1cc(NCCCc2cccnc2)c2n[nH]c(=O)n2c1 +N#Cc1ccc(S(=O)(=O)N2Cc3ccccc3N(Cc3c[nH]cn3)C(CCc3ccccc3)C2)c(Cl)c1 +Nc1nc(SCCN2CCN(Cc3ccccc3Cl)CC2)nc(N)c1Cc1ccccc1Cl +CC(=O)CC(=O)NCCNc1c2c(nc3ccccc13)CCCC2 +Cc1ccccc1Sc1ccc2c(-c3c(Cl)cccc3Cl)c(=O)ncn2n1 +CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1scc[n+]1CC)C(C)=O)OC +CC(=O)Nc1c(C(C)=O)c(O)nc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12 +COc1ccc2c(c1)Cc1c(Nc3cccc(OCC(C)C)c3)n[nH]c1-2 +CC(=O)N1CC=C(c2cccnc2OC2CN(c3nc4ccccc4s3)C2)CC1 +O=c1[nH]c2ccc(C3=NCCN3)cc2c2c1sc1ccccc12 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCCC2CCC2)cc1F +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C=C(F)C(=O)NCCN1CCCC1 +CCn1c(=O)n(-c2cccc(C(F)(F)F)c2)c2c3cc(-c4ccc(N)nc4)ccc3ncc21 +S=C(NCc1cccnc1)SCCc1nnc(-c2ccc3ccccc3n2)o1 +CCN(CC)C(=O)Oc1ccc2c(c1)OC(=Cc1ccc(OCCN3CCCC3)cc1)C2=O +CS(=O)(=O)c1ccc(C(=O)NC(=S)NCCC2CCN(Cc3ccccc3)CC2)cc1 +CCc1c(C)[nH]c(=O)c(N(C)C(C)COC)c1Cc1cc(C)cc(C)c1 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+COc1ccc2c(c1)[n+]([O-])c(C#N)c(-c1ccc(Cl)cc1)[n+]2[O-] +CC(C)Oc1cc(Nc2nc(NC(C)c3ccc(F)cc3)ncc2Cl)n[nH]1 +CC(Nc1nc(Cl)cc(N2C(=O)OCC2C(C)O)n1)c1ccc(C(C)(F)F)cc1F +COc1ccc2c(CCNC(=O)c3cc(=O)c4c(OCc5ccc(Br)cc5)cccc4o3)c[nH]c2c1 +Cc1ccc(N2CCN(C(=O)C3CN(C4CCOCC4)CC3c3ccc(Cl)cc3)CC2)c(C(N)C(C)C)c1 +CCCC(=O)Nc1ccc2c(c1)-c1ccccc1C(=O)C2=O +Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2cc3ccncc3[nH]2)cc1 +CC(C)C(O)CC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2cc(F)ccc2[nH]1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCCCC3)cc12 +CCOc1ccccc1N1CCN(CCCNC(=NC#N)c2ccccn2)CC1 +O=C(Nc1sccc1-c1nc(O)c(O)c(C(=O)O)n1)OCc1ccccc1 +O=C(O)COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2 +CC(C)(C)OC(=O)NCCCCCNC(=O)C1C(C(=O)Nc2ncc(Br)s2)C2CCC1C21CC1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2cccnc2O)c1 +NC(=O)c1cccc(-c2ccc3c(c2)sc2c(N)ncnc23)c1 +O=C1C(CC(F)(F)F)=CC(O)(CSc2ccncc2)N1CCNc1ccnc2cc(Cl)ccc12 +Cc1ccc(CNCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(=O)NCC2CC2)c(C)c1 +Cn1cc(-c2ccc(Cn3c(CC4(C(=O)O)CCCC4)nc4cc(OCc5ccc6ccccc6n5)ccc43)cc2)cn1 +C=C1C(=O)OC2CC3(C)CCC4(C)C(CCC5C6(C)CCC(=O)C(C)(C)C6CCC54C)C3C12 +CN1CCCN(Cc2ccc(-c3ccc(CN4CCCN(C)CC4)c(Cl)c3)cc2)CC1 +COc1ccc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)Nc2ccc(C(=O)Nc3ccc(F)cc3N)cc2)cc1 +COc1cc(-c2cc(C)c(=O)n(C)c2)ccc1CN(C)C +COc1cc(C(=O)NC2CCc3cc(OC)c(OC)c(OC)c3-c3ccc(OC)c(=O)cc32)cc(OC)c1OC +COc1ncc(C(=O)NC2(C(=O)NC3COc4cc(-c5cc(Cl)cc(F)c5-c5noc(C)n5)ccc43)CC2)cn1 +CC(C)(C)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 +CN1CCN(c2ccc(C(=O)Oc3ccccc3)cc2NC(=O)c2ccc(F)c([N+](=O)[O-])c2)CC1 +CNC(C)c1ccc(C(=O)Cn2ncc(OCc3ccc(OC)cn3)cc2=O)c(C)c1 +Cc1ccc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NC2CCC(C)CC2)cc1 +Cc1cc(NC(C)CCC(C)C)n2nc(C)c(-c3cnc(N(C)C)cc3C)c2n1 +O=c1[nH]c(=O)n(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)cc1F +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4C5CCC4CNC5)cn3)nc2n1C1CCCC1 +CC(=O)c1ccccc1-c1ccc2[nH]c(C=Cc3ccc(C(C)(C)C)cc3)nc2c1 +N#Cc1cc2c(O)c(-c3cccc(-c4ccc(F)c(F)c4)c3)c(O)nc2cc1Cl +C#Cc1cn2c(-c3ccc(C(=O)NCC(F)F)c(C)c3)cnc2c(NCCC(F)(F)F)n1 +CC(C)n1c(=O)cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc21 +N#CC(Cc1ccc(-c2ccc(S(N)(=O)=O)cc2)cc1F)NC(=O)C1NC2CC1C1CC21 +CC1(N(Cc2ccccc2)CC(O)C(Cc2ccccc2)NC(=O)OC2COC3OCCC23)C(=O)Nc2ccccc21 +Cn1c(=O)c2nc(-c3ccccc3O)[nH]c2n(C)c1=O +CCCCCCCCC#Cc1ccc2c(c1OC)CC(CO)NC(=O)C(C(C)C)N2C +CC1NC(C)(C)COC1(O)c1cccc(-c2cccc3ccccc23)c1 +Clc1ccc(-c2cc(-c3ccncc3)c(-c3ccccc3)[nH]2)cc1 +Cn1c2ccccc2c(=O)c2c(=O)n(Cc3ccco3)c(COc3ccccc3)nc21 +COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCCc2ccccc2Cl)C(C)C)C(C)C)ccc1OC +Cc1onc(-c2ccccc2)c1COc1ccc(C#N)cn1 +c1ccc2c(NCCCCCCCCCNc3c4c(nc5ccccc35)CCCC4)ccnc2c1 +Cc1nc(-c2cn3c(n2)-c2cc(-c4ccnn4C4CCCN(C5COC5)C4)c(F)cc2OCC3)n(C(C)C)n1 +CC#CCOc1ccc(S(=O)(=O)NC(C(=O)NO)c2ccc(OCCNC)cc2)cc1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(Br)s3)CC2)nc1 +O=C(Nc1cnc2ccccc2c1)c1ccnn1CCc1ccncc1 +CC1CN(C(=O)c2ccccc2)CCN1c1nnc(-c2ccccc2)c2ncccc12 +Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc2c(c1)C(=O)NC2=O +CC1(C)CNc2c(cccc2S(=O)(=O)NC(CCCN=C(N)N)C(=O)N2CCC(CC(F)F)CC2)C1 +NC1(c2ccc(-c3nn4ccccc4c3-c3ccccc3)cc2)CCC1 +O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(cnn2CCN2CCOCC2)c1 +Fc1ccc(-c2c[nH]c(C3CCN(c4ncnc5[nH]ccc45)CC3)n2)cc1C(F)(F)F +N#Cc1ccc(-c2ccc3c(c2)C2(CCCCC2)C(=O)N3)[nH]1 +COc1ccc2c(c1)C(CCCN1CCN(c3cccc(C(F)(F)F)c3)CC1)CCC2 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1ccnc(OC(F)F)c1 +COCCCOc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1cc(NC(=O)CCc2ccc3[nH]c(-c4ccc(Cl)s4)nc3c2)ccc1N1CCOCC1=O +O=C1CC(c2cccc(-n3ccnn3)c2)=Nc2ccc(C(F)F)cc2N1 +CN(C)c1cc(Oc2ccc3c(c2)CC(NCC(O)c2ccc(Cl)nc2)CC3)cc(C(=O)O)c1 +CCOC(=O)C(O)=CC(=O)c1cn(Cc2ccc(F)cc2)c2c(OC)ccc(OC)c12 +O=S(=O)(NCC1CCC(CNC2CCc3cc(F)ccc3C2Cc2cccnc2)CC1)c1ccccc1 +CN(C)CCCNc1nc(NCc2ccc(C(F)(F)F)cc2)nc(NCc2ccc(C(F)(F)F)cc2)n1 +O=C(O)CCn1c2c(c3cc(NS(=O)(=O)c4ccc(F)cc4)ccc31)CCCC2 +O=C(O)C1CC2(CCN(c3ccc(-c4nc5ccc(C(F)(F)F)cc5[nH]4)cn3)CC2)Oc2ccccc21 +CCOC(=O)C(=O)CC(=O)C=Cc1cccn1Cc1cc(F)cc(F)c1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC(F)F)CC3)c(Cl)c2)c1C#Cc1ccc(NC)nc1 +COc1ccc2cc(-c3nn(C(C)(C)C)c(N)c3C(N)=O)cnc2c1 +CSCCN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21 +CC(Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 +CC1(C)C=CC2=C(O1)C(=O)c1ccccc1C2=O +CC(NC(=O)c1ccnnc1)c1ccc(OC2CCN(c3ccnc(OCC(F)F)c3)C2)cc1 +O=C(NC(CCCCNc1cccc2ccccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21 +OC(CNC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1)COc1ccc(F)cc1 +COc1cccc(C(=O)c2cc(OC)c(OC)c(OC)c2)c1 +COc1ccc(CCNc2cc(-c3cccc(S(C)(=O)=O)c3)nc(OC)n2)cc1 +O=C(Nc1cc(C(=O)N2CCC(O)(CO)CC2)nn1-c1ccccc1)c1cc(-c2ccccn2)c(F)cc1Cl +CNc1ccc(C=Cc2ccc(OCCCCCCCCF)cc2)cc1 +Cc1nc(C)n(-c2ccc(Nc3cc(-c4ccn(C)n4)c(F)cn3)cc2)n1 +CCCNC(=O)C1CCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)CC1 +CCCCCN1C(=O)C2(COc3cc(F)c(F)cc32)c2ccccc21 +O=C(NCCC1CCN(Cc2ccccc2)CC1)c1cc[n+]([O-])cc1 +CC(=NN=C(S)N1CC2CCC(CC2)C1)c1cnc(C)cn1 +CCCN(CCC)C(=O)Cc1c(-c2ccccc2)nc2ccc(C(=O)OC)cn12 +CC(=N)N1CCC(Oc2ccc(N(Cc3ccc(-c4cccc(C(=N)N)c4)cc3)S(C)(=O)=O)cc2)CC1 +COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O +O=C(NC1CCCCC1)c1ccc2[nH]c(-c3ccc(NC(=O)C45CC6CC(CC(C6)C4)C5)cc3)nc2c1 +CC(C)c1noc(COc2ccc(Cl)cc2OC2CNC2)n1 +O=C1N(Cc2cccc(Cl)c2)CCCC12CCN(c1nc3ccccc3[nH]1)CC2 +O=C(O)CC1CCc2c(c3ccccc3n2Cc2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)C1 +Cc1c(Br)cccc1C(=O)NCC1(c2ccc(C(F)(F)F)nc2)CCC(F)(F)CC1 +O=C(c1ccccc1)C1Cc2ccc(cc2)OCCCCC(C(=O)NO)C(CCCc2cc(Br)cc(Br)c2)C(=O)N1 +CC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cncc(N)c1 +CC(C)CCn1c(CN2C(=O)C(=NOc3ccccc3)c3ccccc32)nc2ccccc21 +O=C(O)C(=O)C1Cc2ccccc2CN1S(=O)(=O)C=Cc1ccccc1 +CC1(C)Cc2c(-c3ccccc3)c(-c3ccc(Cl)cc3)c(CC(=O)NS(C)(=O)=O)n2C1 +Cc1nc(N2CCN(C(=O)CC(C)C)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +O=S(=O)(c1cccc(F)c1)c1ccc2oc3c(c2c1)C1CCC(C3)N1 +CN(C)c1cc[n+](CCCCCCCCCCC[n+]2ccc(N(C)C)cc2)cc1 +COC1CC2(C)C(CCC3C4CCC(=CC#N)C4(C)CC(=O)C32)CC1O +CC(C)(C#N)c1cc(Cn2cncn2)cc(Sc2ccccc2)c1 +Cc1ccc(-c2ccc3n(c2=O)CC2CNCC3C2)s1 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+O=C(O)c1cccc(-n2c(Cl)ccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 +CCOC(=O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +Nc1c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc2n1CCN1CCOCC1 +Nc1ncc(-c2nc(N3CCOCC3)c3ccc(Nc4cccnc4)cc3n2)cn1 +COc1ccc(C(Cc2ccncn2)c2ccccc2)cc1OC1CCCC1 +COc1ccc(C)cc1NC(=O)OC1CC23CCCCC2(CC(NCc2ccccc2)C3)C1 +Cc1cccc(NC(=O)Nc2ccc(-c3ccc(N)c4c3CNC4=O)cc2)c1 +COc1ccc(-c2ccc(CSc3nnc(-c4ccncc4)o3)cc2)cc1 +[C-]#[N+]c1ccc(C(=O)Nc2cc(F)c(F)c(C3(C)CC(C(F)(F)F)OC(N)=N3)c2)nc1 +NCc1ncc(C23CCC(N(CCN4CCCC4)C(=O)Nc4ccc(F)c(C(F)(F)F)c4)C2C3)s1 +FC(F)(F)Cn1cc(C(NC2CCN(c3ccc(C(F)(F)F)cc3)CC2)c2cccnc2)cn1 +Cc1cc(Cl)cc(Cl)c1CC(=O)NC1COc2nc(Cl)ccc21 +O=C(NS(=O)(=O)c1ccc(F)cc1)N1CCC(N2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)CC1 +O=C(CSc1ccccc1)NCCCN1CCC2(CCc3ccccc32)CC1 +O=c1c2cn[nH]c2c2ccc(-c3ccc(C(F)(F)F)nc3)cc2n1CC(F)(F)F +CN1CCc2c(c3cc(C(F)(F)F)ccc3n2CCc2ccncc2)C1 +O=C(NC(CNC(=O)C1CCCn2c(C=CC3CCNCC3)nnc21)C(=O)O)OCc1ccccc1 +CC(C)Oc1ccc(NC2=CC(O)N(CC(=O)NC(CO)CO)C(=O)N2Cc2ccc(Cl)cc2)cc1F 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+CCCCNC(=O)C1CC(Cc2ccccc2)CN1C(=O)C(N)CC +Cc1c(C#N)[nH]c2ccc(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)cc12 +Cc1cc(C(F)(F)F)ccc1CCc1cc(O)c(=O)[nH]n1 +COc1ccc(CC(Cc2ccc(NS(=O)(=O)O)cc2)(c2nc(C)no2)c2nc(C)no2)cc1 +CNC(=O)c1cccc2c1C(NC)CCC2c1ccc(Cl)c(Cl)c1 +CC(=O)c1c(C)cc(C)c(CSc2nc3ccc(NC(=O)c4ccc(C(C)(C)C)cc4)cc3s2)c1C +COc1ccc(OC)c(C(c2c(C)n[nH]c2O)c2c(C)n[nH]c2O)c1 +CC(=O)Nc1nc(C)c(-c2cnc(-c3cccnc3)o2)s1 +N#Cc1ccccc1Cn1c(N2CCCC(N)C2)ncc(Cl)c1=O +COc1cc2nccc(Oc3ccc4c(C(=O)Nc5ccc(Cl)cc5)cccc4c3)c2cc1C(C)=O +CCCCN1C(=O)C2Cc3c([nH]c4ccccc34)C(c3ccoc3)N2C1=O +COc1cccc(CNC(=O)c2cc3ccc(-c4cn[nH]c4)cc3n2CCN(C)C)c1 +CCc1c(C(=O)N2CCc3cc4ccnc(N5CCN(CC)CC5)c4cc32)cnn1-c1ccc(C#N)cc1 +COC(=O)C(CC(C)C)NC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2 +CC1(c2cc(NC(=O)n3ccc4cc(Oc5ncnc6c5CNC6)ccc43)n[nH]2)CC1 +COc1cccc(N(C)CC(=O)N2CCCC(c3ccccc3)C2CN2CCCC2)c1 +COCCCn1nc(C)c2ccc(C(C)N(C(=O)C3CNCCN3)C3CC3)cc21 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(OC(F)(F)F)c2)c1 +CC1CN(C(=O)C2CN(c3cccnn3)CC2c2ccc(F)cc2F)CC(C)C1(O)c1ccccc1 +Cc1cc(NS(C)(=O)=O)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(-n2ccnc2C)s1 +CC(Nc1nccc(-c2c(-c3ccccc3)nc3nc(N)ccn23)n1)c1ccccc1 +CCOc1ccc(-n2c(C(C)N(C(=O)Cc3ccc(F)c(C(F)(F)F)c3)C3CCOCC3)nc3ncccc3c2=O)cc1 +Cc1cc(C)cc(Sc2c(CNC=O)c(C)[nH]c(=O)c2I)c1 +Oc1cc2c(cc1O)CN(C(=S)NCCc1ccc(Cl)cc1)C2 +O=S(=O)(NCCCCCc1c[nH]cn1)NCc1ccc(Cl)cc1 +CCC(NC(C)CO)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F +CC1(c2cccc(Nc3ccccc3OC(F)F)c2)COCC(N)=N1 +O=C(NC1CC1)c1ccc(Cl)c(Nc2nncc3c2cnn3-c2c(F)cccc2F)c1 +Nc1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +COc1ccc(-c2nc3c(C(=O)NCC(=O)N4CCCC4C#N)ccnc3[nH]2)cc1 +Nc1ccnc(N2CCC(C(=O)Nc3ccc4ccccc4n3)(c3ccccc3)CC2)c1 +CCC(CC)n1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)c(-c2cccc(C(F)(F)F)c2)c1C +O=C1Cc2ccccc2N1CCCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +N#CN=C(Nc1ccc(F)cc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +Nc1ncc(-c2cccnc2)c2scc(-c3cccc(NC(=O)Nc4c(F)cccc4F)c3)c12 +O=C(Nc1cc(-c2ccccc2)cn(CC2CC2)c1=O)N1CCC(n2cc(-c3ccccc3)[nH]c2=O)CC1 +COCCOc1ccc(N(Cc2cnccc2C)C2CCN(C(C)CCNC(=O)c3c(C)cc(F)nc3C)CC2)cc1 +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)NCc1cccc(Br)c1 +CC(=O)c1cnc(N2CCn3c(nc4cc(CO)c(S(C)(=O)=O)cc43)C2C(C)C)nc1C(F)(F)F +O=C(O)c1ccc(NC(=O)c2c(Oc3ccc(F)cc3)cc(C(F)(F)F)cc2C(F)(F)F)cc1 +CCc1sc2ncnc(NN=C(C)c3cc(O)ccc3O)c2c1C +CCCCCCCC=CCCCCCCCC=C1CC(C=CC(=O)OC)(CO)OC1=O +Cc1ccc(C(=O)CSc2nc(O)c(C(C)C)c(Cc3cccc4ccccc34)n2)c(C)c1 +O=c1c2c[nH]nc2c2ccc(Nc3cccnc3)cc2n1CC(F)(F)F +Cc1ccccc1C(=O)NC(Cc1ccccc1)C(=O)CCC(=O)N1CCCC1C(=O)O +Cc1ccc(C(C)n2c3ccccc3c3c(N)nc(-c4ccccc4)nc32)cc1 +CC(Nc1cc(-c2ccc(N(C)C)cc2)nc(-n2cnc3ccncc32)n1)c1ccccc1 +CC(C)CC1(C(=O)O)CC(C(=O)Nc2ccccc2)C(c2nccs2)N1C(=O)c1ccc(C(C)(C)C)cc1 +O=C(NC1COCC1C(=O)NO)c1ccc(Cn2c(C(F)(F)F)nc3ccccc32)cc1 +COc1ccc2c(c1)CCN(c1noc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n1)C2 +COCC(C)Oc1ccc2[nH]nc(-c3cc(N4CCCC(F)(F)C4)ncn3)c2c1 +COc1cccc(CC2C(O)C(O)C(Cc3cccc(OC)c3)N(CC3CC3)C(=O)N2CC2CC2)c1 +CCONC(=N)c1ccc(-c2ccc(-c3ccc(C(=N)NOCC)cc3)o2)cc1 +COc1cccc(CN2C(=O)C3(N=C2N)c2cc(CCC4CC4)ccc2CC32CCC(OC)CC2)c1 +Cc1cc(C)c(Oc2cc(Nc3ccc(C#N)cc3)nc3ncnn23)c(C)c1 +CCN(CC)C(=O)C1CCC2C3CN(CC)C4=CC(=O)CCC4(C)C3CCC12C +COc1cccc(CNC(=O)C#Cc2cn(Cc3ccc(C(=O)O)cc3)c(=O)[nH]c2=O)c1 +CN1CCN(c2ccc(Nc3ncc4cc(C#N)c(=O)n(C5CCCC5)c4n3)cc2)CC1 +CCCC(=O)Nc1cc(-c2ccc3c(c2)OCO3)nc(-c2ccccc2)n1 +Cc1cccnc1-n1nc(C)c(-c2ccc(OC3CCN(C4CCC4)CC3)cc2)cc1=O +OCCN1CCN(c2ccc3cc2COCC=CCOCc2cccc(c2)-c2ccnc(n2)N3)CC1 +O=C(NCc1ccc(S(=O)(=O)N2CCCCC2)cn1)N1Cc2cn[nH]c2C1 +Cc1nc2sc(C(=O)NCc3ccc4c(c3)OCO4)c(N)c2c(C)c1Cl +CCN(CC)c1cccc(Nc2nc(Nc3cccc(NC(C)=O)c3)nc3c(C#N)cnn23)c1 +N#Cc1cc(Oc2ccc(-c3cccc(C(O)C(O)C(N)=O)n3)cc2)ccc1C(F)(F)F +Cc1cc(COc2ccc(S(=O)(=O)N3CCN(C4CCC4)C(C(=O)NO)C3)cc2)c2c(n1)CCCC2 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCC3CCNC(=O)C3)c12 +CCCS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O +N#CCOc1ccc(Nc2nc(Nc3cccc(O)c3)ncc2F)cc1 +COc1cccc(OC)c1C1CCCCC(=O)N1Cc1ccc(-c2ccccc2)cc1 +C=CC(=O)Nc1cccc(CC)c1Nc1ncc(OCc2c(Cl)c(OC)cc(OC)c2Cl)cn1 +CCCn1c(=O)c2nc(-c3cccnc3)[nH]c2n(CCC)c1=O +CC(C)OC(=O)N1CCC(Oc2cccc3c2CCN3c2ccc(S(C)(=O)=O)cc2)CC1 +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2ccccc2Cl)c(C)c1 +Cc1nccn1-c1ccc(-c2cn(CC(=O)Nc3cccc(Cl)c3Cl)nn2)cn1 +CC(NC(=O)Nc1cc2[nH]nc(NCc3ccccc3)c2cn1)c1ccccc1 +O=C1Cc2cc(C(=O)NC3CC4CCC(C3)N4S(=O)(=O)CC3CCNCC3)ccc2N1 +COc1cccc2c3c(=O)n(C4C5(C)CCC(C5)C4(C)C)ccc3n(CCN3CCOCC3)c12 +CC(C)(O)CN1CCC(NC(c2ccc(Cl)cc2)c2cccnc2)CC1 +O=C(NC(=S)Nc1ccc(S(=O)(=O)N(Cc2ccc(O)cc2)c2ccccc2)cc1)c1ccc2cccnc2c1 +Cc1ccc(CN2CCN(CC(=O)N3c4ccccc4CC3C)CC2)cc1F +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3scnc3C)cc2)C(=O)C(C)C)c1 +O=C(Nc1ccc(O)cc1OCC(O)CN1CCC2(CC1)Cc1cc(F)ccc1O2)NC1CC1 +CS(=O)(=O)c1ccc(-c2c(-c3ccc(F)cc3)nn3nc(S(C)(=O)=O)ccc23)cc1 +[N-]=[N+]=Nc1ccc(C(=O)NCCCCCCC(=CC(N)C(=O)O)CP(=O)(O)O)cc1 +N=C(N)NCCCC1C(=O)N(S(=O)(=O)c2ccc(-c3ccccc3)cc2)C1C(=O)O +CCOC(=O)N1CCC(n2cnc(-c3ccc(F)cc3)c2-c2ccnc(N)n2)CC1 +Cn1cc(C=C2C(=O)Nc3ccc(S(N)(=O)=O)cc32)c2ccccc21 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+CCOC(=O)c1ccc(COC2CCN(c3ccc(C)nn3)CC2)cc1 +Cc1ccc(C)c(-c2cc(-c3ccc(F)cc3)c(C=CC3CC(O)CC(=O)O3)c(C(C)C)n2)c1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CN(C(=O)c5ncco5)CC4C3)nc21 +COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCOCC5)cc4)c(OC)cc23)c(Cl)cc1Cl +O=C(CCc1cccc2ccccc12)NC1=C(C(=O)O)CCCC1 +CCCCCCCCCC(CC(=O)NO)C(=O)NC(C(=O)NC)C(C)(C)C +COc1ccc(S(=O)(=O)n2ccc3ccnc(-c4ccc(F)cc4)c32)cc1 +OC1(c2ccc(Cl)cc2)CCN(CCCCc2ccc(F)cc2)CC1 +OCC1OC(n2cnc3c(NCC=Cc4ccccc4)ncnc32)C(O)C1O +Clc1ccc(C2=Nn3c(nnc3-c3cccnc3)SC2)cc1Cl +Cc1nc(N2CCC(O)(CCO)CC2)nc2ccc(NC(=O)C=Cc3ccc(Cl)cc3)cc12 +O=C(NCc1ccc(Cl)cc1Cl)N1CCC(Oc2ccccc2)CC1 +O=S1(=O)C=Cc2cc(-n3cc(-c4ccc(OC(F)(F)F)cc4)nn3)ccc2O1 +CCOc1ccc2c(c1OC)CN1CCc3cc(OC)c(O)cc3C1C2 +CC(C=CC1CC2(CO2)CC(C)(C)O1)=CCC1CCC(NC(=O)C=CC(C)OC(=O)N(C)CCN(C)C)CC1 +O=C(NC1CCN(c2ccccn2)CC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCC2=Cc1ccc(F)cc1 +CC1Nc2cc3c(cc2C1C)c(C(F)(F)F)cc(=O)n3C +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCCNCC1 +COc1ccc(-c2nc3cc(-c4nc5cc(CCN(C)C)ccc5[nH]4)ccc3[nH]2)cc1 +COc1cc(-c2cnc(C)n2C)ccc1Nc1cc2cc(-c3cnn(CC(F)(F)F)c3)ccc2cn1 +N#Cc1cncc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)c1 +CCN(c1cc(OC)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +COc1cc(-c2ccc3c(c2)OCO3)cc(C=O)c1O +COc1cc(Oc2ncccc2-c2n[nH]c(Nc3ccc4c(c3)OCO4)n2)cc(OC)c1OC +CN(CCCCCCCN1C(=O)c2ccccc2C1=O)Cc1cccc(Cl)c1 +Cn1cc(C2=C(C(=O)CBr)C(=O)NC2=O)c2ccccc21 +Cc1cc(-c2nnc(NCC3OCCO3)o2)nc2c(C(C)(C)C)cc(OCC(F)(F)F)cc12 +Cc1ccc(Cn2c(=Nc3ccc(OC(C)C)c(F)c3)[nH]c(=O)n(CC(=O)NC(C)C(=O)O)c2=O)cc1 +Clc1ccc(-n2cncn2)c(Cc2nc3c(NCCC4CCCCN4)nccc3o2)c1 +CCC(=O)NC(C(=O)N1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C +CC(O)(COc1ccc(Cl)c(F)c1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3cnc4[nH]ncc4c3)c2)c2cncnc21 +Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3)ccc12 +Nc1ncnc(N2CCC(C(O)c3ccc(F)cc3)CC2)c1-c1ccc(F)cc1 +O=C(c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1ccc(N2CCC(O)C2)nc1)C1CC1 +CCn1nc(-c2cccc(-c3ccc(O)cc3F)c2)cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O +COCCCNC(=O)c1cn2cc(-c3cnc(N)nc3)nc(N3CCOCC3)c2n1 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F +O=C(O)CC(NC(=O)c1cncc(S(=O)(=O)NC2CC2)c1)C(=O)CSCc1ccc(F)cc1 +COC1COCCC1NC1CC2OCCC2(C(=O)N2COc3ccc(C(F)(F)F)cc3C2)C1 +CN1C(=O)C(=C2CC(c3ccccc3)N(C(=O)CCl)N2)C(=O)N(C)C1=O +CCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)CC(C)S3)cc1 +COc1ccc(Cn2c(C(N)=O)cc3c2-c2nc(Nc4ccccc4)ncc2CCC3)cc1 +N#Cc1cccc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)c1 +O=C(CCCCc1ccn(Cc2ccc(OCc3ccccc3)cc2)n1)NO +O=C(NC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1)c1ccccn1 +CCOc1ccc(NC(=O)c2ccc(Cl)nc2)c([N+](=O)[O-])c1 +CCN1CCCC(n2cc(S(=O)(=O)c3ccc(Cl)s3)c3cccnc32)C1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1NC(=O)c1cncnc1 +CCc1c(COC(=O)NC)c(COC(=O)NC)c2n1-c1ccccc1C2 +CC(NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1)C(C)(C)C +CCN1C(=Cc2cc[n+](CC)c3ccccc23)C=Cc2ccccc21 +Clc1ccc2c(NCCCCCCCNc3c4c(nc5ccccc35)-c3ccccc3C4)c3c(nc2c1)CCCC3 +Cc1c(-c2ccnc(N)n2)sc2ccc(C(N)c3ccccc3)cc12 +CCCCCCC(C)CC1=C(O)C(=O)c2c(C)cccc2C1=O +CC(C)CCC(=O)C(CC1CCCCC1)NC(=O)C(CC(C)C)NC(=O)Cc1ccccc1 +CC(C)n1cc(-c2cnc(Nc3cccc(Cn4nc(-c5cnn(C)c5)ccc4=O)c3)nc2)cn1 +Cc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)s1 +CC(=O)c1cnc2ccc(-c3ccc(O)cc3)cc2c1NC1CCC(CN(C)C)CC1 +COCCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(Br)cc2)c1 +O=C(Cc1cccc2cnccc12)Nc1scnc1-c1cnccn1 +C=CCN(C)CCCCCCOc1ccc2c(-c3ccc(Br)cc3)coc2c1 +CNC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 +Fc1ccc(-n2cc(OCCN3CCOCC3)c3cc(Cl)ccc32)cc1 +O=C(Nc1nccc2ccccc12)C1CCC(N2C(=O)C3C4CCC(C4)C3C2=O)CC1 +NC(=O)COc1ccc(C=C2SC(=O)N(CC(=O)O)C2=O)cc1 +N=C(N)NCCCC(NC(=O)c1coc(C(c2ccccc2)c2ccccc2)n1)C(=O)O +Cc1cc(C)cc(-n2nc(C)c3c(=O)oc4ccccc4c32)c1 +Cn1ncc(C(=O)N2C3CCC2CC(Nc2n[nH]c4ccc(F)cc24)C3)c1Cl +CC1(C)CCC(C)(C)c2cc(C3(c4ccc5cc(C(=O)O)ccc5c4)SCCS3)ccc21 +Cc1cccc(C)c1N1CC(CN(C)C)(C(=O)Nc2cc(C3CC3)cc(C(F)(F)F)c2)C(C)C1=O +CCN(CC)c1nc(NC(=O)Nc2ccccc2)c2ccccc2n1 +COc1ccc2ncc(C(F)(F)F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +CCCN(CCCCCCNc1nc(N)n2nc(-c3ccco3)nc2n1)CCc1cccc2c1CC(=O)N2 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+N=C(N)c1ccc(NC(=O)c2ccc3c(c2)NC(CC(=O)O)CN(CCc2ccccc2)C3)cc1 +Nc1nc2c(cnn2CCCc2ccc(C(=O)O)cc2)c2nc(-c3ccco3)nn12 +CC(O)C1OC(OC2C(N)CC(NC(=O)C(O)CCN)C(O)C2OC2OC(CN)C(O)C2O)C(N)C(O)C1O +O=C(c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)N(Cc1ccccc1)Cc1ccccc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1NC1CCC(N)C1 +CS(=O)(=O)Nc1ccc2[nH]cc(C(=O)CN3CCC(Cc4ccccc4)CC3)c2c1 +Oc1c(-c2nnc(Cc3ccc(F)cc3)[nH]2)ncc2cccnc12 +CNS(=O)(=O)Cc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 +COc1ccc(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)cc1C(=O)O +CN1CCC(CNC(=O)Nc2ccccc2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +CC(C)(C)c1ccc(C(=O)NCCCCNc2ccnc3cc(Cl)ccc23)cc1 +O=C(CC1CCNCC1)N1CCC(NS(=O)(=O)c2cc(S(=O)(=O)c3ccccc3)ccc2C(F)(F)F)CC1 +CC(C)c1cc(-n2cc(-c3ccc(CN4CCN(Cc5ccccc5)CC4)cc3)nn2)c(O)cc1O +CN(C)C(=O)c1cccc(-c2cnc(N)c(-c3nc4cccc(N5CCNCC5)c4n3C)n2)c1 +CC(=O)NCC(C)c1ccc(C#Cc2cnc(OC3CCC3)nc2)cc1 +COC(=O)CCc1cnc2c(c1)c(NCCO)c(C(=O)NCc1ccc(F)cc1F)c(=O)n2O +CCC1(C(=O)O)CCc2ccc(OCCCOc3ccc(C(F)(F)F)cc3Cl)cc2O1 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+COc1cc(CC(=O)NCC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)cc(Br)c1N +COC(=O)c1cc2ccccc2cc1-n1nc(C)cc1C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1 +c1cc(NC2CCCC2)n2nc(-c3ccc(OCC4CC4)cc3)c(-c3ccnc(NC4CCCC4)n3)c2c1 +CCCN(C(=O)c1ccc([N+](=O)[O-])c(C)c1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O +O=C(Nc1cc(-c2ccccn2)nn1Cc1ccccc1)c1nc(C2CC2)ccc1Nc1cncnc1 +Cc1nc(NC(C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc(F)c(F)c2)n1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(F)cccc3nc2-1 +COc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCC(N(Cc4ccccc4)C(C)=O)CC3)cc2)cc1 +COc1ccc(-c2cc(NC(C)=O)cc(-n3cnc4cc(-c5cnn(C)c5)ccc43)c2)c(F)c1 +Clc1cnc(NCC2CCCNC2)cc1-c1cccc(NCC2CCOCC2)n1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(C#N)cc3)c2)c2cncc(F)c21 +CCNc1cc2c(cc1Cl)NC(=O)Nc1cnc(C#N)c(n1)OCCCCCO2 +CC1(O)CCC(NC(=O)c2cc(NC(=O)c3cc(-c4ncccc4F)c(Cl)cc3Cl)n(-c3ccccc3)n2)CC1 +COc1cccc(C2=NN(c3ccccc3)C(c3ccc(Br)cc3)C2O)c1 +NC(=S)Nc1ccc2c(c1)Cc1cc(NCc3ccccc3)ccc1-2 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-c3cnco3)ncc(F)c12 +CN(C(=O)Nc1cnc(-c2ccccc2)cn1)C1CCC2(CC1)OC(=O)c1ccncc12 +O=C1C(NS(=O)(=O)c2ccc3c(Cl)c[nH]c3c2)CCN1c1cc2c(cc1F)CNCC2 +CCC(c1cc2c3c(c1)CCN3C(=O)CC2)n1ccnc1 +Cc1cc2c(cc1C=Cc1ccsc1S(=O)(=O)Nc1onc(C)c1Br)OCO2 +CNC(=O)Nc1cc(CCOc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1 +COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)ccc2Cl)cn1 +CN1CCN(c2cc(C(=O)N(C)Cc3ccccc3)c3ccccc3n2)CC1 +CCN(C1CCC(N2CCN(c3ccccc3OC(C)C)CC2)CC1)S(=O)(=O)c1ccc(OC)c(OC)c1 +O=[N+]([O-])c1ccc2sc3c(Nc4cccc(Br)c4)ncnc3c2c1 +Cc1ccc(N2CC(O)=C(C(=O)Nc3ccc(OCCCCCCCn4cnnn4)cc3)C2=O)cc1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Oc2cccc(CCCC(=O)O)c2)cc1 +COCCc1sc[n+](CCCCc2cccc(CCCC[n+]3csc(CCOC)c3C)c2)c1C +COc1ccc(OC)c(C2CC(=O)C3=C(C2)NC(=O)CC3c2ccc([N+](=O)[O-])cc2)c1 +Cc1cc(Cl)c(C(=O)Nc2cc(C(=O)NCC(C)(C)O)nn2-c2ccccc2)cc1-c1ncccc1F +COc1cc(CNC(=O)C2(Cc3ccccc3F)OC(=O)N(C(C)c3ccccc3)C2=O)cc(OC)c1 +O=C(O)C(=O)Nc1ccc(NC(=O)c2cc(Br)c(Br)[nH]2)cc1 +Cc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CCC2)cc1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)C)C1c1ccccc1C(F)(F)F +CCN(CC)C(=S)NCCCNc1ccnc2cc(Cl)ccc12 +O=C(Cc1ccc(F)cc1)NC(=O)Nc1ccc(Oc2ccnc3[nH]cc(C(=O)NCc4cccnc4)c23)c(F)c1 +CCCN(CCCC(=O)OCC)CCc1cccc2c1CC(=O)N2 +CC#CCOc1ccc(S(=O)(=O)N2CC(S)C2)cc1 +COc1cc(-c2cc(C#N)c(NC(C)c3ccc(F)cc3)nn2)ccc1-n1cnc(C)c1 +Cc1ccc(Nc2ncnc3c2nnn3Cc2ccccc2Cl)cc1 +N#CC1CCCN1C(=O)CNC1CCC(NC(=O)C2CCCCC2)CC1 +CCOC(=O)CCCCC(=O)c1[nH]c(O)nc1CN1CCOCC1 +CN1C(=O)C(NC(=O)NCc2ccccc2)N=C(c2ccccc2)c2ccccc21 +CN1C(=O)CCc2cc(-c3cncc(CC(=O)Nc4cccc(Cl)n4)c3)ccc21 +COC(=O)C(C)(C)NC(=O)c1ccc(N2CCCC2)c(OCC2CC2)n1 +CCCCC(N)C(=O)Nc1ccc(C(=O)NC(Cc2ccc(O)cc2)C(=O)OC)cc1N +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)c2ccc3c(cnn3CCCNc3ccccn3)c2)C(=O)O)c(C)c1 +O=C(NC1CN2CCC1CC2)c1cc2cccc(F)c2s1 +Cc1cc(C)c(S(=O)(=O)NC(Cc2c[nH]c3ccc(C#N)cc23)C(F)(F)F)c(C)c1 +Cc1cc2nc(CCc3nc4c(C)ncc(C)n4n3)ccc2cc1F +CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)COC)nc21 +O=C(Nc1cc2cc[nH]c(=O)c2cc1Cl)C1CCNC1 +Cc1n[nH]c(C)c1-c1cccc(-c2cnc(N)c(C(=O)NC3C4CC5CC3CC(O)(C5)C4)n2)c1 +O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O +CC(C)(C)OC(=O)NC(Cc1ccc(NS(=O)(=O)O)cc1)c1nc(-c2cccc(C(F)(F)F)c2)cs1 +O=C(NCc1ccc(S(=O)(=O)c2ccccc2)cc1)N1Cc2ccccc2C1 +O=C(NCc1ccc(S(=O)(=O)c2cc(F)cc(F)c2)cc1)c1cc2cnccc2[nH]1 +CC(=O)OC1CCC2(C)C(CCC3C2CCC2(C)C(c4ccc(=O)oc4)CCC32O)C1 +CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1cccc(N2CCN(c3cccc(Cl)c3)CC2)c1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)CCC1=NNCCN12 +Cc1nccn1-c1cnn(C)c(=O)c1-c1ccc(CC(NC(=O)c2c(Cl)cccc2Cl)C(=O)O)cc1 +N#Cc1ccc(Oc2ccc(-c3cccc(CNCCN4CCNC4=O)n3)cc2)cc1 +CCn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC(N)C(OC)CC1 +COc1ccc(F)c(-c2ccc(C3CCc4ccc(C(C5CC5)C(C)C(=O)O)cc4O3)nc2)c1 +O=C(C=Cc1ccc(Br)cc1F)N1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1 +O=C(CC1CCN(S(=O)(=O)c2ccccc2)CC1)N1CCC(C2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c32)CC1 +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)C=C(c1c(O)c(-c3cccs3)nn(CC3CCCC3)c1=O)N2 +O=c1c(N2CCc3ccccc32)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCN(C6CC6)CC5)ncn4)c3c2)cn1 +COC(=O)C1C(c2ccc(-c3cccc(F)c3)cc2)CC2CCC1N2C +CC(C)CC(NC(=O)C(CCc1ccccc1)CP(=O)(O)CCCCNC(=O)Nc1ccccc1)C(=O)Nc1ccccc1 +CCOC(=O)CCc1ccc(CCNc2nc(N)c3ncn(C4OC(CO)C(O)C4O)c3n2)cc1 +CC(=O)NCC1OC(n2cnc3c(NC4CC5CCC4C5)ncnc32)C(O)C1O +N#Cc1ccc2c(c1)C(=O)NC(C(=O)NC1(C#N)CC1)Cc1ccc(c(Cl)c1)OCCCCO2 +CC(Oc1cc2onc(CCC(=O)O)c2cc1Cl)c1ccc(F)cn1 +C=CCn1c(NS(=O)(=O)c2ccccc2)c(C#N)c2nc3ccccc3nc21 +Cc1cc(NC(=O)CCNC(=O)Nc2nc(C)c(-c3ccc(S(C)(=O)=O)c(F)c3)s2)no1 +CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)Cc2ccc(Cl)cc2F)ccc1Oc1ccc(F)cc1F +NC1CCN(C(=O)c2ccc3[nH]c(-c4cc5ccccc5nc4O)cc3c2)C1 +COC(=O)Nc1nc2cc(C(=O)c3cc(CC(=O)OC(C)(C)C)cs3)ccc2[nH]1 +O=C(Nc1cccc(O)c1C(=O)O)c1ccc(Br)c(Oc2ccccc2)c1 +c1cncc(Cc2nnc(-c3ccc(N4CCC5(CCc6ccccc6O5)CC4)nn3)o2)c1 +CC1(F)C(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)OC1(C#N)c1ccc2c(N)ncnn12 +Cc1cc2c(cc1Cl)N(C(=O)Nc1ccc(Oc3cnccc3C)nc1)CC2 +N#Cc1ccc(C(=O)NC(=S)N2CCc3c(OCCCCCOc4ccc(Cl)cc4)cccc32)cc1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)nc3cc(CN(C)CCO)ccn23)n1)c1ccccc1 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+CN(C)C1CC=C2C=C3CCC4(C)C(c5ccc6ccncc6c5)CCC4C34CCC2(C1)O4 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NC3CCCCCC3)CC2)c(C)c1 +CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCOCC1)c1ccc(NS(C)(=O)=O)c(F)c1 +O=C(O)c1ccc(C=NOC(c2ccc(OCc3ccc4ccccc4n3)cc2)C2CCCCC2)cc1 +CC(C)N(CC1CC2c3ccccc3Cc3ccccc3N2O1)C(C)C +Cc1sccc1C1(c2cccc(-c3cncnc3)c2)N=C(N)N(C)C1=O +COCC(C)Oc1cc(OC(C)Cc2ccccc2OC)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 +CN(C)c1ccc(-c2c(COc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cn1 +CS(=O)(=O)Nc1ccc(C(=Cc2c(C(=O)O)[nH]c3cc(Cl)cc(Cl)c23)C(=O)O)cc1 +CCCN(C)CCC1=C(Cc2cnccn2)c2ccccc2C1 +CCCS(=O)(=O)NC(C(=O)NC(CCSC)C(=O)NCc1ccc(C(=N)N)cc1)C(C)O +O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2-c2ccccc2)c1)NO +CC(=O)NC(Cc1ccc(F)cc1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +COc1ccc(-c2cncc(C(F)(F)F)c2)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C(O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 +CC(=N)N1CCC(Oc2ccc3c(c2)OCC(=O)N3Cc2cccc(-c3cccc(C(=N)N)c3)c2)CC1 +CCNc1nc2ccc(C#CC(C)(O)c3cc(C)on3)cc2n1-c1ncnc(N)n1 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+O=c1c(Cc2ccccc2)c[nH]c2c(-c3cccnc3)cnn12 +CCCCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1 +CCCCn1cc(C(=O)c2cccc3ccccc23)c2cccc(OC)c21 +CCC(C)(C)C(=O)OC1C(CO)C(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C21 +CN(C)C(=O)N1CCN(C(c2cncnc2)c2ccc(Cl)cc2F)CC1 +Nc1[nH]c2ccccc2c2nc(-c3ccccc3)nc1-2 +O=C(NCCCCCCS)c1cc(-c2ccccc2)n[nH]1 +NCCCN(CCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)CC1CC1 +CCn1cc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cccc(Cl)c2)C(N)CC3)cn1 +Cc1cc(=O)[nH]nc1-c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 +Nc1ncc(-c2ccc(-c3ccc(C(F)(F)F)cc3S(=O)(=O)NCCO)cn2)cn1 +CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(NC(=O)c2cc3c(cn2)COC3)n1 +CCN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(F)cc2)[nH]c2ccccc12 +Cc1nc2n(c(=O)c1CCN1CCN(c3cccc4c3CCS4)CC1)CCCC2O +C=CCNC(=O)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 +Cc1ccc2c(c1)C(=Nc1ccc(NC(=O)Nc3ccc(S(N)(=O)=O)cc3)cc1)C(=O)N2 +CNC(C)C(=O)NC(C(=O)NC1CCCN(C(=O)Cc2ccccc2)C1)C1CCCCC1 +Cc1ccc(C2=NN(c3nc(-c4ccc(Br)cc4)cs3)C(c3cccs3)C2)cc1 +COc1c(OCC(O)CN(C)C)ccc2c1N=C(NC(=O)c1cccnc1)N1CCN=C21 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+[O-][n+]1nc2c(I)cnn2c2cc(Oc3ccccc3)ccc21 +O=C(Nc1ccc(-c2ccc(O)cc2)cc1)Nc1ccc(-c2ccnc3[nH]cnc23)cc1 +CCCCC1Nc2cc(NC(=O)OCC)nc(N)c2N=C1C +CCCCCCNC(=O)Oc1cccc(-c2cc(C(=O)OCC)nn2-c2ccccc2)c1 +Cc1cc(Nc2n[nH]c3ncc(F)cc23)nc(C2CCCCC2)n1 +CN(C)Cc1ccc(-c2ccc(NC(=O)Nc3cccnc3Oc3ccccc3C(C)(C)C)c(F)c2)cc1 +CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2C2CC(O)CCC21 +Cn1cc(-c2cnn3c(N)c(-c4ccoc4)c(C4CCCNC4)nc23)cn1 +CC(C)Nc1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CCCc1[nH]c(=O)c(Cc2cc3cc(OC)ccc3nc2NCCOC)c2cc(OC)c(OC)cc12 +COc1cccc(CC(=O)Nc2nc(-c3ccnc(F)c3)cs2)c1 +Brc1cccc(Nc2ncnc3ccc4cc[nH]c4c23)c1 +[H]C([H])([H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1OCC1CCC1 +COc1ccc(Nc2nccn(C(C)C3CC3)c2=O)c(C(F)(F)F)n1 +O=C(NC(Cc1c[nH]c2ccccc12)C1=NNC(CCc2ccccc2)N1Cc1cccs1)C1CCNCC1 +COc1nccc2c1C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2cccc3ccccc23)cc1 +Oc1cccc(-c2nc(N3CCOCC3)c3[nH]ccc3n2)c1 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NC)cc2C)ncn1 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+COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(sc5cccc(OC)c54)c3=O)CC21 +[N-]=[N+]=NCC1OC(n2cc(Br)c3c(Cl)ncnc32)C(O)C1O +CCNC(=O)C1OC(n2cnc3c(N)nc(NCCN4CCN(c5ccc(C(F)(F)F)cc5)CC4)nc32)C(O)C1O +N#Cc1ccc(N2C(=O)C3C(O)CCN3C2=O)c(F)c1F +CN1C2CNCC1CC(NC(=O)N1CC(C)(C)c3ccccc31)C2 +c1cc(Nc2ncnc3ccc(-c4ccc5[nH]ncc5c4)cc23)c2cn[nH]c2c1 +CNC(=O)c1c(NC(=O)c2nc(N3CCN(C)CC3)cnc2Nc2cncnc2)cnn1C +CNC(=O)C(CC(C)(C)C)NC(=O)c1cccc(Cc2ccc(F)cc2)n1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC1CCC(N)C1 +Cn1cc(-c2cnc(N)c3c(-c4ccc5c(c4)CCN5C(=O)Cc4ccccc4)csc23)cn1 +CCN1CC=C(c2c[nH]c3ccc(NC(C)=O)nc23)CC1 +Cc1nc(-c2ccc3c(c2)c(C#N)cn3Cc2ccccc2)sc1C(=O)O +Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(C)c3cccc(Cl)c3)cc12 +C=CC(=O)Nc1cccc(-n2cnc3cnc(Nc4ccc(OC)cc4)nc32)c1 +COc1cc(C(=O)c2ccc(-c3csc(NC(=O)C(N)Cc4ccc(F)cc4)n3)cc2-n2cncn2)cc(OC)c1OC +CC1CCCC(N2CCC(c3c(F)ccc(Cl)c3F)=CC2=O)c2cc(ccn2)-c2ccc(C#N)cc2NC1=O +COc1cc(F)cc2c1nc(C)c1c(C)nc(-c3cnccc3C)n12 +C=CCN(C(=O)OCc1ccc([N+](=O)[O-])cc1)C1CCN(CCC(Cn2cnc3ccccc32)c2ccccc2)CC1 +Cc1cc(=O)n(CCCOc2cccc(Cl)c2)c(N2CCNCC2)n1 +COc1ccc(NC(=O)Nc2ccc(Cn3cc4c(=O)[nH]cnc4n3)cc2)cc1 +O=C1CCCCCN1Cc1nnc(SCc2nc3ccccc3s2)n1-c1ccccn1 +COC1(c2ccccc2)CCN(Cc2ccn3c(CC4CC4)nnc3c2C(F)(F)F)CC1 +CC1=C(C(=O)c2ccc(F)c(F)c2)C(c2cccc(O)c2)NC(=S)N1C +CCOc1ccc(Cc2nnc(CN(c3cccc(Cl)c3Cl)S(=O)(=O)c3ccc(C(F)(F)F)cc3)o2)cc1 +O=c1cc(-c2ccccc2)oc2cc(OCCN3CCN(c4ccccc4)CC3)ccc12 +O=C(O)c1ccc(OC2CCN(C(=O)NC3CC3c3ccccc3)CC2)cc1 +CC1CN(CCOC(=O)C2Cc3ccc(O)cc3CN2)CCC1(C)c1cccc(O)c1 +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +COc1ccc2c(c1)CCOC21CCN(CCC(C(=O)NCc2cc(F)cc(C(F)(F)F)c2)c2ccc(F)cc2)CC1 +C=C(CN1CCOCC1)C(=O)Nc1cc2c(cc1OC)nc(Nc1ccccc1C)c1cncn12 +Cc1c(Cl)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 +Cc1nn(C2CCCC2)c(C)c1S(=O)(=O)NC(C)CNc1cccc2c1cnn2-c1ccc(C#N)cc1 +Cc1ccc(S(=O)(=O)N2CCc3cc(C(=O)NCCN(Cc4ccc(Cl)cc4)C(C)(C)C)ccc3C2)cc1 +NC(=O)c1cccc2[nH]c(-c3ccc(C4CCCNC4)cc3)nc12 +CN(C)CCCN1c2ccccc2CCc2ccc(C#CCOCCOCCc3cccc4ccccc34)cc21 +O=C(NCc1ccc(Cl)cc1)c1cc2cccc(O)c2cc1O +Cc1cc(NC(=O)c2cnn3cccnc23)n(-c2cc(C#N)ccc2C)n1 +COCCNC(=O)Nc1cc2[nH]nc(OC)c2c(COC)n1 +C=CC(=O)NC1CCN(c2nc(Nc3ccc(N4CCN(C)CC4)cc3)c3ncn(CCO)c3n2)C1 +N#Cc1ccc(C(=O)CC2CCN(CC3CC3)CC2)cc1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC(C(=O)O)C1 +CC1CCN(C2CCN(c3ccc(Nc4ncc5cc6n(c5n4)C4(CCCCC4)CNC6=O)nc3)CC2)C1 +CCc1ccc2c(c1)sc1nc(C(=O)c3ccccc3)cn12 +N=C(N)c1ccc(Oc2ccc3c4ccccc4n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)cc1 +Nc1nc(N)c2nc(CCc3ccc(C(=O)NC(CCCNC(=O)c4ccccc4C(=O)O)C(=O)O)cc3)cnc2n1 +CN1CCc2ccc(C(=O)CCCN3CCC(c4ccc(Cl)cc4)CC3)cc2CC1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(F)cc1-c1ccc(F)nc1 +Nc1ncnc(N2CCC(Cc3ccc(Cl)cc3)CC2)c1Br +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(NC2CCc3cc(Br)ccc32)C1 +CCC(C)C(=O)OC1CCC=C2C=CC(C)C(CCC(=O)CC(O)CC(=O)O)C21 +COc1ccc(CNC2COC(C(c3ccccc3)c3ccccc3)CC2O)cc1F +COC(=O)CCc1ccc(OCC(O)CNC(C)(C)C)cc1 +CC1(C)CC=C(c2cc(C3(N4CCOCC4)CCOCC3)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +Cc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc([N+](=O)[O-])c(N2CCC(C(=O)O)CC2)cc1Cl +CCCNC(=O)NCc1cnc2c(ccn2-c2cc(NC(C)C)c(C(=O)NCC(F)C(C)(C)O)cn2)c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2Cl)c1F +O=C1NC(=S)SC1=Cc1cc(-c2csc3ccccc23)ccc1OCc1ccccc1 +CN(C(=O)c1ccccc1)c1nc(-c2ccncc2)cs1 +c1cc2c(ncn3nnc(C4CCN(Cc5cncs5)CC4)c23)[nH]1 +CC(=O)NC1(Cc2cccc(Nc3nccs3)n2)CCC(Oc2cccc(Cl)c2F)CC1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1-c1nccn1C +CCN(c1cc(-c2ccc(CN3CCOCC3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1Cl)C1CCOCC1 +CC(C)(O)c1cccc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)n1 +CC1=CC(C)(C)Nc2ccc(-c3cc(Br)c(C#N)s3)cc21 +CN(C(=O)OCCOc1ccc2c(c1)CN1CC(=O)NC1=N2)C1CCCCC1 +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(sc5cc(C#N)ccc54)c3=O)CC21 +COCCNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC)ncc1Br +CCC(CC)n1cc(C(=O)NCc2ccc(S(C)(=O)=O)cn2)c(=O)c(-c2cccc(C(F)(F)F)c2)c1C +Nc1ccccc1NC(=O)c1cc2ccc(N3CCNCC3)cc2cn1 +CNC1CCC(N(Cc2cccc(-c3ccncc3)c2)C(=O)c2sc3ccccc3c2Cl)CC1 +c1ccc2sc(Oc3ccc(OCCCN4CCCCC4)cc3)nc2c1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CNCC(O)C(Cc1ccccc1)NC(=O)OCCO 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+COc1ccc(-c2ccc3ncnc(Nc4cccc5[nH]ncc45)c3c2)cc1C=O +c1ccc(CN2CCN(CCCc3ccc(C(c4ccccc4)C45CC6CC(CC(C6)C4)C5)cc3)CC2)cc1 +CCN(CC)CCNC(=O)c1cccc2cc3cccc(I)c3nc12 +CCCCCCCCNC(=O)C(Cc1ccc(OCc2cccc(N)c2)cc1)NC(=O)C1CCC(CN)CC1 +CCCCn1cc(C(=O)c2cccc3ccccc23)c2c(O)cccc21 +NS(=O)(=O)OCC1CC(Nc2cc(NC3CCCc4ccccc43)ncn2)C(O)C1O +Cc1cc(C)c(Oc2cc(Nc3ccc(C#N)cc3)[nH]c(=O)c2)c(C)c1 +Cc1cccc(-c2ccc3c(N4CCOCC4C)nc(N4CC(C)OC(C)C4)nc3n2)c1 +N=C(N)c1ccc(OC(=O)c2ccc(CN3CSCC3C(=O)NC(CC(=O)O)C(=O)O)s2)c(F)c1 +Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 +Cc1ccsc1-c1cn(-c2ccc(C(=O)O)c(O)c2)cc1C#N +COc1cc(OCc2cccc(-c3ccc(C(=O)N(C)C)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C1CC(=O)CC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1 +CCCOC(=O)C1(C)CCC2(C)CCC3(C)C4=CC=C5C(=CC(=O)C(O)=C5C)C4(C)CCC3(C)C2C1 +CC(O)(COc1ccc(F)cc1)C(=O)Nc1ccc(F)c(C(F)(F)F)c1 +CCCCc1ccccc1Oc1cccc(CCCC(P(=O)(O)O)S(=O)(=O)O)c1 +COCC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(C(C)(C)C)cc1)C2 +CCCCc1ccc(S(=O)(=O)NC2CCC3C4CCc5cc(O)ccc5C4CCC23C)cc1 +COc1ccccc1-c1cc2c(NC(CO)c3ccccc3)ncnc2s1 +Cn1nc(C(C)(C)C)cc1NC(=O)C(=O)c1ccc(-c2ccc(CN3CCOCC3)nc2)c2ccccc12 +Cc1ccc(NC2=C(N3CCCCC3)C(=O)c3ccccc3C2=O)cc1 +CCN(CC)CCOc1ccccc1CNc1nnnn1-c1cccc(Cl)c1Cl +CC1(O)CCN(c2ccc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)C1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2ccccn12 +FC(F)Oc1ccc(-c2ccnc3cc(-c4cccc(Cl)c4)nn23)cc1OCC1CC1 +COc1cc(Nc2nc3n(n2)CCCCC3c2ccc(OCC(F)(F)F)cc2)ccc1-n1cnc(Cl)c1 +O=C(c1ccccc1F)c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12 +COc1cc(OC)c2ncn(CC=C3c4ccccc4COc4ccc(C(=O)O)cc43)c2c1 +COc1cc(C(=O)NC2CC3CC(C)CC(C2)N3)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1)CC2 +NS(=O)(=O)c1ccc(NC(=O)CSc2nnc(C(F)(F)F)n2-c2cccc3ccccc23)c(Cl)c1 +CCC(F)(F)c1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(F)c2)c1 +O=C(NC1CCN(Cc2cccc(Br)c2)CC1)c1cccc2ccccc12 +CCOc1cccc(-c2cc(C#N)ccc2C#CC(O)(c2ccc(C#N)cc2)c2cncn2C)c1 +COc1cc(OC)cc(N(CCCNC(=O)C(F)(F)F)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1 +CC1CN(Cc2ccccc2)c2ccccc2C(C)N1C(=O)Nc1cccnc1 +NC1CC2CCC(C1)N2C(=O)C(Cc1ccc(Cl)cc1Cl)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1 +Cc1cccc(-n2ncc3c(N(C)C4CCCCC4)ncnc32)c1 +OC(CN1CCC(c2ccccc2)CC1)c1ccc(Br)cc1 +CC(C)C(=O)Nc1ncc(SCc2ncc(C(C)(C)C)o2)s1 +CN1CCN(c2cnc3cc(C(F)(F)F)cc(OCc4cccc([N+](=O)[O-])c4)c3n2)CC1 +CC(Nc1cc(-c2ccoc2)nc(-n2cnc3ccncc32)n1)c1ccccc1 +COc1cc(CN2CCOCC2)ccc1NC(=O)Nc1cnc(C#N)cn1 +CCNC(=O)c1cnn(-c2nc(NC)c3ncn(C4OC(CO)C(O)C4O)c3n2)c1 +CCCCN(C)C(=O)Cc1c(-c2ccc(Cl)c([N+](=O)[O-])c2)nc2c(Cl)cccn12 +O=C(NC1Cc2ccccc2N(Cc2n[nH]c(-c3ncc[nH]3)n2)C1=O)c1cc2cc(Cl)ccc2[nH]1 +O=C1N(CCO)CN(c2ccccc2)C12CCN(C1CCc3cccc(Cl)c3C1)CC2 +CCCN(CCC)Cc1ccc(-c2ccc(CCN3CCCCC3)cc2)cc1 +CC(=NOCCO)c1ccc2nnc(C(C)c3cc4cccnc4cc3F)n2n1 +CC1Oc2nc(cnc2N)-c2c(nc3ccc(C#N)cn23)CN(C)C(=O)c2ccc(F)cc21 +COC(=O)c1cccc2c3cc(-c4ccccc4)n(CC(=O)NC(C(=O)C(F)(F)F)C(C)C)c(O)c-3nc12 +O=C(O)CCCCON=C(c1ccccc1)C(Cc1ccc(Cl)cc1)n1ccnc1 +NC(=NC(=O)CCCCCCCCCCCCCCC(=O)N=C(N)NCCCc1c[nH]cn1)NCCCc1c[nH]cn1 +CC(C)(C)OC(=O)NCCCC(=O)Nc1ccc(S(N)(=O)=O)cc1 +C#CC(C)(C)N1CCN(c2cc3c(cc2C(C)=O)C(=O)c2c([nH]c4cc(C#N)ccc24)C3(C)C)CC1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(Oc2ccccc2)cc1)Cc1cccc(CCCC(=O)O)c1 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)Cc3ccc(F)cc3)c2cn1)c1ccccc1 +CC(C)Oc1ccccc1N1CCN(Cc2ccc(C(=O)N3CCCCCC3)s2)CC1 +COc1ccc2c(c1NC(=O)C(C)(C)CCCCCCOc1ccc(Cl)cc1)C(=O)CCO2 +CCOC(=O)C1CCN(C(=N)c2ccc(C(=O)Nc3c(OC)cc(Cl)cc3C(=O)Nc3ccc(Cl)cn3)c(F)c2)CC1 +Cc1ccc2nc(Cc3nc(N4CCOCC4)cc(=O)[nH]3)oc2c1 +CCN(Cc1cc(NS(=O)(=O)c2ccc(Cl)cc2)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1 +N#Cc1cccc(C23CCC(N(CCN4CCC(O)C4)C(=O)Nc4cccc(Br)c4)CC2C3)c1 +COc1ccc(Nc2c3c(nc(N)n4nc(-c5ccco5)nc34)nn2C)cc1 +CCN1C(=Cc2sc3ccccc3[n+]2CC)C=Cc2ccccc21 +CS(=O)(=O)N(CC(=O)N1CCCC(c2ccccc2)C1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2ocnc2c1 +CCCc1cnc(N2CCC(n3nnc4c(Nc5ccc(S(C)(=O)=O)cc5F)ncnc43)CC2)nc1 +Cc1c(NS(=O)(=O)c2ccc(CCCCC3CCNCC3)cc2)c(CC(C)C)nn1C +O=C(CCN1CC2CC(C1)c1cccc(=O)n1C2)c1ccc(F)cc1 +CCCCNc1cc(-c2oc3ccccc3c(=O)c2-c2ccc(F)cc2)ccn1 +OCCCn1cnc2ccc(-c3c(-c4ccccn4)nn4c3CCC4)cc21 +COc1ccc2c(CN3CCC4(CC3)CN(c3ccc(C(=O)O)cc3)C(=O)O4)cn(-c3ccccc3)c2c1 +CN(C)CCc1cccc(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)c1 +COc1ccc(C(=O)N(CCC2CCCN2C)CC(C)=Cc2ccc(F)cc2)cc1OC +COc1cc(S(=O)(=O)c2ccc(C3CCOC3)cc2)cc2c3c(oc12)CCNC3 +O=C1NC(=O)C2(CCN(c3nc4ccccc4n(C4CC5CCC(C4)N5C4CCCCCCC4)c3=O)CC2)N1 +Cc1nc(-c2ccc(OCCNCC(O)c3cccnc3)cc2)c(C)o1 +O=C(O)C1CN(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CCO1 +CN(C)C1CCC2(Cc3ccccc3Cc3ccccc32)C1 +CC(OCc1ccc(-c2ccccc2)cc1)(C(=O)NO)C(O)c1ccccn1 +NS(=O)(=O)c1cc(S(N)(=O)=O)c(NC(=O)CN(CCN(CC(=O)O)c2ccccc2O)c2ccccc2O)cc1Cl +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1cccc2ccccc12 +O=C1c2ccccc2NC12CC13CCN(CC4CC4)C(Cc4ccc(O)cc41)C3(O)C2 +C=CC(=O)Nc1cccc(CNc2nc(Nc3cnn(CCOCC)c3)ncc2Cl)c1 +Cc1cc(CC(NC(=O)N2CCC(c3cccc(Cl)c3)CC2)C(=O)N2CCC(N3CCCCC3)CC2)cc2cn[nH]c12 +COC(=O)c1cc(S(N)(=O)=O)ccc1S(=O)(=O)CCCO +CCCC1CCC(N2CCC(N3C(=O)NC4CCCCC43)CC2)CC1 +CCCCC(C=NNC(=O)N1CCc2ccccc21)NC(=O)OC1(Cc2ccccc2)CCCC1 +O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(NCc2ccc(C(F)(F)C(=O)O)cc2)c1 +Cc1ccc2c(c1)-c1nc(N)nc(-c3ccc(C)o3)c1C2 +O=S(=O)(c1ccc2c(c1)C1CNCC2C1)N1CC1 +CC(Nc1cc(F)ccc1Cl)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +COc1ccc(C(c2ccccc2)c2c[nH]c3ccccc23)cc1 +COc1ccc(C)cc1CN1CCCC(C(=O)N(Cc2cc(Cl)c3c(c2)OCCCO3)CC(C)C)C1 +Cn1cc(-c2cc(C(=O)N3CCCC3CO)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +CCC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3cc(C)c[n+]([O-])c3)c2)CC1 +CCc1cc2c(cc1N1CCN(C(=O)C3CCCCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +O=C(NC1CCC(CNCc2cc(-c3ccccc3)on2)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1[nH]c2ccc(OC3CCN(C(C)C)CC3)cc2c1C(=O)N1CCOCC1 +CNC1CCC(c2ccc(Cl)c(Cl)c2)c2ccc(CC(N)=O)cc21 +CN1C(=CC=Cc2oc3ccc(Cl)cc3[n+]2C)Sc2ccccc21 +Fc1ccc(Nc2nc(Nc3ccc4[nH]cnc4c3)ncc2Br)cc1 +c1ccc(CCc2ccc(C3=C(Cc4ccccc4)c4ccccc4C4=NCCCN43)cc2)cc1 +O=c1[nH]c2ccc(Cl)cc2c(=O)n1CCCCn1ccnc1 +CCC1(CCCCN2CCN(c3ccc(OC)cc3)CC2)C(=O)Nc2ccccc21 +O=C(OC1C2CC3CC(C2)CC1C3)N1CCCC1c1nc(-c2ccncc2)cs1 +NC(=O)C1Cc2ccccc2CN1C(=O)CC(N)Cc1ccccc1F +O=C(c1c(F)cccc1F)N1CCc2c(cnn2-c2ccc(F)cc2Cl)C1 +COc1cc2c(cc1OC)-c1n[nH]c(-c3ccc(Br)nc3)c1C2 +Nc1nc(O)c2ncn(-c3cccc(C(F)(F)F)c3)c2n1 +CNC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 +O=C(Nc1ccc(C(=O)N2Cc3ccccc3C2)cc1)N1Cc2ccccc2C1 +CC1CCC(c2ccccc2)S(=O)(=O)N1Cc1ccc(N2CCC(CO)(n3cnnc3)CC2)cc1F +COc1ccc(-n2nc(C3CCN(S(=O)(=O)C4CC4)CC3)cc2NC(=O)c2cnn3cccnc23)c(F)c1 +CCCCN1CCC(C(=O)NO)(S(=O)(=O)c2ccc(OC)cc2)CC1 +Nc1nc(N)c2c(OCC3CCN(S(=O)(=O)c4cccc5ccccc45)CC3)cccc2n1 +CCCCCCCCC(=O)N(CC(C)C(=Nc1ccccc1)Nc1ccccc1)c1ccccc1 +CN1CCN(c2ccc(-c3ccc4[nH]c5nccc(Nc6ccccc6[N+](=O)[O-])c5c4c3)cc2)CC1 +CN1C(=O)C(c2cccc(-c3cccnc3)c2)(c2ccc3c(c2)OCO3)N=C1N +CC(C)c1cccc(-n2nc(C#N)c(=O)n(CCCN3CCCCC3)c2=O)c1 +O=C1NC(=O)C(c2ccc(Oc3ccccc3)cc2)(N2CCCN(C(=O)N3CCOCC3)CC2)C(=O)N1 +CC1(C)c2n[nH]c(Nc3nccc(C(F)(F)F)n3)c2CN1C(=O)NC1CC1c1ccccc1 +O=C(CN(c1ccc(Br)cc1)S(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1)NCCc1ccccc1 +CCc1csc(C(Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)C(Cc2ccccc2)NC(=O)CC(=O)OC)n1 +NC(=O)C(=O)N1CCCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +NS(=O)(=O)N1CC(C(=O)Nc2ccc(Cl)cc2)C(C(=O)Nc2ccc(-n3ccccc3=O)cc2F)C1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)cc2Cl)NC(CCN2CCCCC2)C1=O)c1ccccc1 +O=C(CCCCCNC(=O)NC1CCCCC1)NC(Cc1ccccc1)C(=O)N1CCCC1C(=O)O +O=C1NC(NCC23CC4CC(CC(C4)C2)C3)=NC1=Cc1c[nH]c2ncccc12 +O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc3ccccc3c2)n1 +Cc1cc(Cl)ccc1-c1cc(COc2ccc(C(CC(=O)O)c3nccn3C)cc2)ccc1C +CCOC1CN(c2ccc(Nc3nnc4cc(-c5c(C)cccc5C)cc(C)c4n3)cc2)CCO1 +CN1c2ccccc2C(NCCCCCCC(=O)NCCCCCNc2c3c(nc4ccccc24)CCCC3)c2ccc(Cl)cc2S1(=O)=O +Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2ncccc2F)s1 +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 +COc1ccc2[nH]nc(NC3CCN(Cc4ccc5c(c4)OCO5)CC3)c2c1 +COC(=O)C1CCC(Nc2cnc3cc(OC)c(OC)cc3n2)CC1 +CCCCCCC[n+]1c(C=Cc2ccc(N(CC)CC)cc2)sc2ccccc21 +O=C(Nc1cc(OC2CCOC2)cc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1 +COc1ccc(CNC2(c3nc(-c4ccc(C)cc4)c[nH]3)CCCC2)cc1 +COc1ccc2c(c1)c(C(=O)C=C(O)C(=O)O)cn2Cc1c(C)cc(C)cc1C +CCCN(c1ccccc1Br)S(=O)(=O)c1ccc(O)cc1 +CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)C1CN(C(=O)C2CCCCC2)CC1c1ccccc1 +CCC(CC)CN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +CCCCCNC=C1C(=O)CCC2(C)C1=C(O)C(=O)c1cc3c(cc12)C(=O)C=CC3=O +CC(C)C(=O)N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +Cc1cc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)N2CCCCC(N(C)C)CC2)c(C)cc1Cl +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)c1ccccc1N1CCCCC1 +Cc1noc(-c2ccccc2C(=O)N2C3CCC2C(COc2cccc(C(F)(F)F)n2)C3)n1 +Cc1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(-c3ccc(F)cc3F)no2)n1 +O=c1[nH]c(NCCO)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +COC(=O)CCCCCCCCOC(=O)C=CCC1OCC(NS(=O)(=O)CCCCl)C(O)C1O +O=C(CCCN1CCN(Cc2ccc(F)cc2)CC1)NC1c2ccccc2SCC2CCCCC21 +CC1CCN(c2cnc3c(c2)C(O)c2cccc(C#N)c2C=C3)CC1 +Cc1c(OCCCCCN2CCCCC2C)ccc2c(=O)cc(-c3ccccc3)oc12 +COc1ccc(-c2cc3c(N)cccc3c(=O)[nH]2)cc1 +OCCOc1cc(CC2CCN(CCc3ccc4c(c3)C(O)CCO4)CC2)ccc1Br +COc1cc(N2CCNCC2)ccc1Nc1nc(N2CCCC2)n2ccnc2c1C(N)=O +CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccccc3)nc21 +CC(=O)OC1CC2C3(C)COC(c4ccccc4)OC3CCC2(C)C2C(O)c3c(cc(-c4cccnc4)oc3=O)OC12C +O=C1Nc2cccc3c2C1(CCCCN1CCN(c2ccccc2Cl)CC1)CCC3 +CC(C)C(NC(=O)Cn1c(-c2ccc(F)cc2)ncc(NC(=O)OCc2ccccn2)c1=O)C(=O)C(F)(F)F +Cc1sc(NC(=O)c2ccc(Nc3ccncn3)cc2)nc1-c1ccc(F)c(C(F)(F)F)c1 +N#Cc1ccc(Cn2cncc2CNC2CCN(c3ccccc3)C2=O)cc1 +CC(=CCOP(=O)(O)OP(=O)(O)O)CCC=C(C)COC(=O)C(=[N+]=[N-])C(F)(F)F +CCOc1ccc(Br)cc1-c1cc2nc(N)nc(N)c2cc1C +COc1ccc2c(C)cc(NC3CCCC(NCc4cccc5nsnc45)C3)nc2c1 +NC(=O)CNCC1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +O=C(c1cc(-c2ccccc2O)on1)N1N=C(c2cccnc2)CC1c1ccccc1O +CN(C)C1CCCC1Nc1nc(Nc2ccc([S+](C)(=N)[O-])cc2)ncc1C(F)(F)F +COc1cccc2c(C(=O)NCc3cccc(C4CCC4)n3)nc(N)nc12 +Cc1ccc2c(c1)c(C#N)cn2-c1nc(C)c(C(=O)O)s1 +O=S(=O)(c1cccnc1)c1sc2ncccc2c1-c1ccc(Cl)cc1 +Cc1nc(NC(=O)c2cc(Cl)cc(Oc3cncnc3)c2)ccc1F +Cc1ccc(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCC1CCN(C)CC1 +COCCOc1ccc2c(OCCn3c(=O)oc4cc(C)ccc43)ccnc2c1 +COc1cnc(-c2cc(Cl)ccc2F)nc1Nc1ccncc1C(=O)NCCNCCO +CC(C)C1CC(C(=O)Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)CCN1 +O=[N+]([O-])c1cc2nc(O)c(O)nc2cc1CN1CCCCC1 +COc1cccc(-c2cc(=O)c3cc(Cl)cc(NCCC(O)CO)c3o2)c1N +CC(=O)C1CCC2C3CCC4CC(O)(C(F)(F)F)CCC4(C)C3CCC12C +COc1cccc(Nc2cc(-c3cccc(-c4cc(C(=O)O)ccc4O)c3)nc3c2C(=O)NCC3)c1 +C=C(C)C(O)C1OC2SC(N(C)C)=NC2C(O)C1O +COc1cc(Nc2ncc(F)c(Nc3ccc4c(c3)OCCO4)n2)cc(OC)c1 +CC1CCCN1C1CCN(c2ccc(N3CCCC4(CCN(C(=O)OC(C)(C)C)CC4)C3=O)cc2)C1 +CC(C#Cc1ccc(Cl)cc1)=CCON=C1CN2CCC1C2 +COc1cc(-c2cn(C)c(=O)c3ccccc23)cc(OC)c1CN(C)C +O=C(C1CCCN(c2ccc3nc(Cc4ccc(Cl)cc4)[nH]c3n2)C1)N1CCCC1 +COc1ccc2c(c1OCc1ccccc1)CC(C(=O)O)N(C(=O)Nc1ccc(F)cc1)C2 +CC(C)Nc1ncc2c(n1)CN(C(=O)NC(CCC#N)c1ccc(Cl)c(Cl)c1)CC2 +COC(C)(c1ccc(F)cc1)c1ccc(C(=O)N(C)CCCCCCC(=O)NO)cc1 +O=C1C(=Cc2ccc(O)c(Br)c2)OC(=S)N1c1ccc(C(F)(F)F)cc1 +CCC(COC)N1CCc2cn(-c3ccc(Cl)cc3C#N)c3nc(C)cc1c23 +CCOC(=O)C1CCC(N(CC)c2cc(Cl)cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c2C)CC1 +CC(C)(C)NCC1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 +COc1ccc(C(=O)Nc2ccc(OC)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCC3)nc12 +Cc1cc(Nc2nc(Sc3ccc(NC(=O)C4CC4)cc3)nn3cc(NC(=O)CCN4CCCCC4)cc23)n[nH]1 +N#Cc1cc(S(=O)(=O)Nc2ncc(F)s2)ccc1Oc1ccc(Cl)c(Cn2cccn2)c1 +CCN(CC)CCCC(C)Nc1cc(-c2ccc(C(F)(F)F)cc2)c(C#N)c2nc3ccccc3n12 +CC1(CC=C2CCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21 +CC(NC1CC1)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +COC(=O)CCCc1onc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1Sc1cccc(OC)c1 +Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(C(F)(F)F)cc(C(F)(F)F)c4)cc3)cc2n1 +CCn1c2c(c(=O)[nH]c1=O)C(c1ccc(C)cc1)C1=C(COC1=O)N2 +O=C(c1ccc(-c2ncccn2)cc1)N1CCC(c2nc3ccccc3[nH]2)CC1 +CN1CCN(c2cc(Nc3cc(C4CC4)[nH]n3)nc(NCc3cc(-c4nccs4)no3)n2)CC1 +Cc1ccc(S(=O)(=O)N2CCC(c3cc(CC(=O)O)cc4ccc(F)cc34)CC2)cc1 +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1N1CCC(c2ccccc2)CC1 +O=C(OC1C[N+]2(CC=Cc3ccccc3)CCC1CC2)C(O)(c1ccccc1)c1ccco1 +Nc1ncnc2c(CN3CC(O)C(CSCc4ccccc4)C3)n[nH]c12 +CCc1cc(CC)n2nc(-c3ccc(OC)cc3)c(CC(=O)N3CCCC3)c2n1 +COc1cc(Br)c(CC(=O)NC(=N)NC(CC(C)C)C(=O)NCc2cccc(-c3nnn[nH]3)c2)cc1OC +COc1cccc(-c2cc(C(N)=O)c3[nH]c4cc(C(=O)N5CCN(C(=O)C6CC6)CC5)ccc4c3c2)c1 +CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)[nH]2)CC1 +O=C(NCCN1CCOCC1)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)CCC4 +Cc1c(S(=O)(=O)NCCCCN2CCC(c3noc4cc(F)ccc34)CC2)sc2ccc(Cl)cc12 +Nc1n[nH]c2cc(-c3nc(C(Cc4ccccc4)NC(=O)c4ccc5c(N)noc5c4)[nH]c3Cl)ccc12 +Cc1cnc(NC(=O)C(c2ccc(Cl)cc2)C(C)C)s1 +CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2Cc2csc(N)n2)n1Cc1ccc(C(=O)O)cc1 +CC(N)C1OC(OC2C(O)C(NC(=O)C(O)CCN)CC(N)C2OC2OC(C(C)O)C(O)C(O)C2N)C(O)C1O +COC(=O)Nc1nc2cc(C(=O)c3cc(CNC(=O)OC(C)(C)C)cs3)ccc2[nH]1 +CCCc1cc(-c2ccc(OC(F)(F)F)c(C(F)(F)F)c2)nc(C#N)n1 +CC1C(=O)NC(Cc2ccc(F)cc2)C(=O)NCC#Cc2ccccc2OCCNC(C2CC2)C(=O)N1C +CC(C)(C)CC(=O)N1CCN(C(c2ccc(Cl)cc2)c2cncnc2)CC1 +Cc1ccc(C(C)NC(=O)COc2cc(C(F)(F)F)c3c(C4CC4)nn(C)c3n2)cc1 +O=Nc1c(-c2c(O)[nH]c3cc(Cl)c(Cl)cc23)[nH]c2ccccc12 +COc1cccc(CO)c1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 +O=C(CCCCCCNC(=O)c1ccc(C(O)(c2ccccc2)c2ccncc2)cc1)NO +O=C(O)c1cc(-c2ccsc2)c2ccc(OCc3c(Cl)cncc3Cl)cc2c1 +N=C(N)NCCCC(NS(=O)(=O)Cc1ccccc1)C(=O)N1CCCC1C(=O)NCc1ccc(C(=N)N)cc1 +COc1cc(-c2ccc3c(-c4ccc5ccccc5c4)n[nH]c3c2)ccc1O +NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)CCO)c(NC2CCCCCCC2)c1F +CCN(CCN(C)C)C(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +Nc1nc(-c2ccco2)c2nnn(Cc3cccc(C(F)(F)F)c3)c2n1 +CC(O)C(=O)N1CCC(CCn2c(Sc3cc4c(cc3Br)CCO4)nc3c(N)ncnc32)CC1 +O=C(NCCCCc1ccccc1)n1c(=O)oc2c(Br)cccc21 +COc1nc(-c2ccccc2Cl)cc2nc(-c3c(Cl)c(C(C)(C)CF)nn3C)[nH]c12 +CC1=NC(C)Cc2c(-c3ccc(C(F)(F)F)cc3)ccc(O)c21 +O=C1N=c2cccc(OCC(O)CNC3CCN(c4ccc(CC5SC(=O)NC5=O)cc4)CC3)c2=N1 +Nc1cccc(CCOc2ccc(CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)n1 +O=C(O)COc1ccc(Br)cc1C=NNc1cccc2cccnc12 +CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccccc21)C(=O)C1CC1 +Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)c5ccccc5)c4)CC3)cccc2n1 +COc1ccc(CNc2cc(OCc3ccccn3)ccc2C(=O)c2cc(OC)c(OC)c(OC)c2)cc1Cl +CCCc1c(OCCCCOc2ccc(-c3nn[nH]n3)cc2)ccc2c1cc(C)n2CC(C)(C)C +O=C(Cc1cccc(C(F)(F)F)c1)NC(Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1 +CN1CCC(c2nc(-c3ccc(F)cc3)c(-c3ccncc3)s2)CC1 +CCC(O)CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +Cc1cc(-c2cc(-c3ccccc3Cl)[nH]c(=O)n2)ccc1O +Cn1ncc2c(c1=O)OCCCN2C(=O)CCNCCOc1cccc(Cl)c1 +O=C1OCc2c1cc1cc(OCc3cccc(C4(O)CCOCC4)c3)ccc1c2-c1cccnc1 +O=c1c2c([nH]c3ccc(-c4ccc(C(F)(F)F)cc4)cc13)CCSC2 +CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)C2CC=C(C)CC32)Sc2ccccc2S1 +NS(=O)(=O)c1ccc(NC(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)cc1 +NC(=O)Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1 +Cc1ccc(NC(=O)c2ccc(Cl)cn2)cc1C1(C(F)F)N=C(N)OC2CC21 +CCC(CO)N1C(C)=CC(=Cc2sc3ccccc3[n+]2Cc2ccccc2)C=C1C +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1(C)CCN(C(=O)C(N)C3CC3)C1)CC2 +CN1CCCCC1COc1cc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)ncc1C#N +CCCCCCCCCC(=O)Nc1ccn(C2COC(CO)O2)c(=O)n1 +Nc1ccccc1C(=O)CCCN1CCC2C(C1)c1cccc3c1N2CCC3 +Cc1cncc(-c2cc3c(-c4cccc(N5CCCNCC5)n4)n[nH]c3cn2)n1 +O=C(NC1CCCc2c1[nH]c1ccc(Br)cc21)c1ccccc1F +CC1=C2c3ccc(O)cc3CC2(c2ccccc2)CCC1=O +O=S(=O)(Nc1ncns1)c1ccc2c(-c3ccccc3Cl)cccc2c1 +NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccccc1F +O=C1OC(=O)c2c1[nH]cc1nc3ccccc3c2-1 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+S=C(NCc1ccccc1)N1CCC(c2c[nH]cn2)CC1 +CC(C)c1cc(C(C)C)c(S(=O)(=O)NCC2CCC(C(=O)NNC(=O)c3cccs3)CC2)c(C(C)C)c1 +Cc1ccc2c(NC3CC3)noc2c1-c1ccc2c(c1)NC(=O)C21CCCC1 +COc1cccc2c3c([nH]c12)CCN(C(=O)C1CCCCC1C(=O)NC1(C#N)CC1)C3 +CC(C)(C)c1nc(CCCCCC#N)c2c(N)c(C#N)c(N)nc2n1 +NC(=S)c1cn(OC2OC(CO)C(O)C2O)c2ncnc(N)c12 +CN1CCN(c2ccc(C(=O)Nc3n[nH]c4cc(OC5CCN(Cc6ccccc6)CC5)ccc34)cc2)CC1 +COc1ccc2c(n1)CCN(C(=O)C1CC(C(=O)O)C1)C2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NC3CCOCC3)c12 +CC(C)C(CC(=O)N1CCc2ccccc2C1)NCC(=O)N1CCCC1C#N +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(NCCO)nc1OC1CCC1 +O=C(O)c1ccc2c(c1)nc(-c1ccc(OCc3cc(N4CCCC4=O)ccc3N3CCCCC3)cc1F)n2C1CCCCC1 +CCc1ccc(C#Cc2c3n(c4ncnc(N)c24)C(C)CC3)cc1 +CCc1c[nH]c2ncnc(N3CCC(N)(CNC(=O)c4ccc(F)cc4F)C3)c12 +CCCCCOc1ccc(C(=O)NCCc2ccc(O)cc2)cc1OCCCCC +CCCn1c(=O)c2[nH]c(Cc3ccco3)nc2n(Cc2ccco2)c1=O +CCCc1cc(C2CCOCC2)ccc1OCCCOc1cccc(C2OC(=O)NC2=O)c1 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCCC2)CCN(C2CCCCCC2)C1 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+COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(C)c5o4)cc3)c3c(N)ncnc32)CC1 +O=C1CCCN1C(=O)C1CC2CCCCC2N1C(=O)C1CC1c1ccccc1 +Cc1cc(SC2=C(O)OC(CCc3nccs3)(C(C)C)CC2=O)c(C(C)(C)C)cc1CO +C=CC(=O)N1CCC(N2C(=O)N(Cc3ccccc3)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)CC1 +CC(c1ccc(COCc2ccccc2)o1)N(O)C(N)=O +N#CC1CC(F)(F)CN1C(=O)CNC(=O)c1ccccc1 +CCN(CC(=O)NCC1CCCN(c2ccc(C(F)(F)F)cc2)C1)S(=O)(=O)c1ccc(F)cc1 +O=C(CCN1CCN(c2ccc(Cl)cc2)CC1)c1ccccc1 +OCC1C(O)C(O)C(O)CN1CCCCCCOC1CCCCC1C1CCCCC1 +CNC(=O)c1c(C(N)=O)nn2c1CCOc1ccc(C#CC3(O)CCN(C)C3=O)cc1-2 +O=C(O)CC(Cc1nc(CCCCNc2cc(N3CCOCC3)ccn2)no1)c1ccc2c(c1)OCO2 +C=CCN1CC(C)N(C(c2ccc(C(=O)N3CCCCC3)cc2)c2cccc(OC)c2)CC1C +N#CC(Cc1ccc(-c2ccc3c(c2)NC(=O)CC3)cc1)NC(=O)C1NC2CCC1C2 +CC1OC(n2cnc3c(NCc4ccc([N+](=O)[O-])cc4)ncnc32)C(O)C1O +N#Cc1cnccc1COc1cnc(N2CC3CCC(C2)N3C(=O)OCC(F)(F)F)nc1 +Cn1c(N(CCCCN)CCc2ccccc2)nc(-c2ccncc2)cc1=O +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C1NC(=O)OC1C +COc1ccc(OC2CCN(c3nc4c(nc3NC(C)C)CCN(C)C4)CC2)c(F)c1 +CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 +O=S1(=O)CCC(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nc2)CC1 +COCCn1cc(-c2ccc3cnc(Nc4ccc(-c5cnc(C)n5C)cc4OC)cc3c2)cn1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCCc1ccc(I)cc1 +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C1CCNC1=O +O=C1C(NC2CCCC2)=C(N2CCOCC2)C(=O)c2ccccc21 +O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c2ccccc12 +CCCCCCSc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +CC1CC(COC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)NC1=O +COc1cc(CC2NCCc3cc(O)c(O)cc32)ccc1O +Cc1cc(-c2nc(-c3ccc(F)c(Cl)c3)n3c2CCOC(CF)C3)cc(C)n1 +CC(C)(C)c1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2CCC2CCCCC2)c1 +CCCCCn1cc(C(=O)c2ccc(CCCC)c3ccccc23)c2ccccc21 +O=C(c1ccccc1NCc1ccc2[nH]ncc2c1)c1n[nH]c2ccccc12 +CCn1c2ccccc2c2cc(Nc3cc(C)nc4ncnn34)ccc21 +N=C(N)N1CCCC(NC(=O)CN2C(=O)C(NS(=O)(=O)Cc3ccccc3)Cc3ccccc32)C1O +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CCNCC4)c4ccccc4n3)c(C)c12 +CCCCCCCc1nc2c3cn[nH]c3[nH]c(=O)n2n1 +Cc1ccccc1Oc1ccc([N+](=O)[O-])cc1S(=O)(=O)NC(=O)NC(C)(C)C +O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc2ccccc2c1 +Cc1ncnc(C#N)c1-c1ccc(Oc2nccc3[nH]ccc23)cc1F +O=c1c(-c2cccc(Br)c2)nc2ccccc2n1Cc1ccccc1 +Cc1nnc2c(Nc3cccc(CNC(=O)c4ccccc4)c3)nc3ccccc3n12 +COc1cccc(NC(=O)Nc2ccc(-c3cc4ccccc4n3C(N)=O)cc2)c1 +Cc1c(C(=O)OCC(C)C)[nH]c2c1C(=O)CC(c1ccco1)C2 +c1cc(C2CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)ccc1OCCN1CCNCC1 +CCN(CC)CCCOc1ccc2c(Nc3ccc(NC(=O)NC4CCCCC4)cc3)ncnc2c1 +CN(C(=O)Cn1c(=O)oc2ccc(-c3ccc(OC(F)(F)F)cc3)cc21)c1cccnc1 +CCC(NC(=O)C1CC(S(=O)(=O)c2ccc(-n3cccn3)cc2)CN1C(C)=O)C(=O)c1nc2ccccc2o1 +CCCOCCOC(=O)c1c(C)nc2sc(C(=O)c3ccc(OC)cc3)c(N)c2c1-c1cc(OC)c(OC)c(OC)c1 +CC1c2nnn(-c3cnccn3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NC(C)c1ccccc1 +CCc1cccc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(C)c34)cc2)c1 +CN1CCN(c2cccc3[nH]c(-c4n[nH]c5cc(-c6ccc(CO)cc6)ccc45)nc23)CC1 +Nc1nc2c(cnn2CCN2CCOCC2)c2nn(Cc3ccccc3)c(=O)n12 +O=C(Cn1nc(-c2ccccc2)cc1-c1ccccc1)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +COc1ccc(C=NNC(=O)C(Cc2c[nH]cn2)NC(=O)c2ccc(OC)cc2)cc1 +N#Cc1c(N)nc(SCc2c[nH]cn2)nc1-c1ccc2c(c1)OCO2 +CC(C)Oc1ccc(S(=O)(=O)N2CCN(c3ccc(C(=O)Nc4cnco4)c(OCC(=O)O)c3)CC2)cn1 +COc1cc(C=CC(=O)NO)ccc1OCC(Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1Cl +COc1cc(-c2cnc(C)n2C)cnc1Nc1cc2cc(-c3cnn(CC(C)(C)O)c3)ccc2cn1 +CCOC(=O)c1cccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)c1 +Cc1cccc(-c2[nH]c(NCc3cccc(C#N)c3)nc2-c2ccc3c(c2)OCO3)n1 +COCCn1cc(-c2ccc3[nH]nc(-c4cc(N5CC(C)OC(C)C5)ncn4)c3c2)cn1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(N3CCCOCC3)nc12 +CC(C)COc1cccc(Oc2cc3c(cc2NS(=O)(=O)C2CC2)n(C)c(=O)n3C)c1 +CCOC(=O)C1=NC2(SC1)C(=O)N(C1CCCCC1)c1ccc(Br)cc12 +CCC1COC(c2ccc3c(C(=O)NCc4cncc(F)c4)c(C(C)C)n(Cc4ccccc4)c3c2)=N1 +Cc1cccc2c1NC(=O)C(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)N=C2c1cccc(Cl)c1 +CCOC(=O)C1C(OC(c2ccc(F)cc2)c2ccc(F)cc2)CC2CCC1N2C +c1c(Nc2nc(N3CC4CCC3C4)nc3c2CCC3)n[nH]c1C1CC1 +Cc1[nH]c2ccccc2c1CCN(CCC(F)F)Cc1ccc(C=CC(=O)NO)cc1 +Cc1cc(Nc2nccc(C3CC3)n2)cc(-c2cnc(C3(N)CCC3)s2)c1 +O=S1NC(c2ccc(S(=O)(=O)N(CCC3CC3)c3sc4ccccc4c3Br)cc2)=NO1 +CN(Cc1ccc(Cl)cc1)C(=O)C1CCCN1C(=O)Nc1ccc(C(F)(F)F)cc1 +N#Cc1cnc2c(Br)cc(NCc3cn(CC(=O)O)nn3)cc2c1Nc1ccc(F)c(Cl)c1 +Cn1cc(-c2[nH]c(-c3ccnc(N)n3)cc2C(N)=O)c2ccccc21 +CCN(CCCCCN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O)CCCc1ccccc1 +c1cc2c(ncn3nnc(C4CCC(CNc5ccc(N6CCOCC6)cc5)CC4)c23)[nH]1 +COc1cccc(-c2c3n(c(=O)n(CC(N)c4ccccc4)c2=O)C(c2ccccc2F)CS3)c1Cl +Cc1cc(C)[n+](CC(=O)NCc2ccc(S(N)(=O)=O)cc2)c(C)c1 +CC(=NNC(=N)N)c1c[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc12 +CC1CN(Cc2ccccc2)c2cc(Br)ccc2C(C)N1C(=O)Nc1cccnc1 +Cc1ccc(-n2nc(C)c3cc(CNCc4cccc(C(F)(F)F)c4)c(=O)[nH]c32)cc1 +Nc1nn2cccnc2c1C(=O)Nc1cn(CC(=O)N2CCC(O)C2)nc1-c1cc(Cl)ccc1OC(F)F +CC(=O)N1CCC(NC(=O)NC2CCC(C)(C)CC2)CC1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 +CN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCCC1 +O=C(NO)c1coc(-c2ccc(-c3ccccc3)cc2)n1 +COc1cc(NC(C)CCCN(Cc2ccc(F)cc2)C(=O)C(C)(C)CCl)c2ncccc2c1 +CN1C(=N)NC(C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CS1(=O)=O +CN(C)CCc1ccc(C2=CCC3CN(Cc4ccccc4)CC23)cc1 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+CCCOCCn1nc(CC)c2nc(N3CCNCC3)nc(Nc3ccccn3)c21 +CN(CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21)C1CC=C(c2c[nH]c3ccccc23)CC1 +CCN1C(=O)c2c(nc(C(N)=O)n2Cc2ccc(O)c(Br)c2)N2C1=NC1CCCC12 +COC(=O)c1c(Cl)c2n3ccccc3c(C)c(-c3ccccc3)c-2c1C(=O)OC +CC1CN(Cc2ccc(Cl)cc2)CC[N+]1(C)CC(=O)N1CCc2ccccc21 +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)NC(C)C)c1cc(Br)cs1 +CCCCCC(=O)N1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2Cl)CC1 +COc1cc2cc[n+](C)c(CCCCc3c4cc(OC)c(OC)cc4cc[n+]3C)c2cc1OC +CCS(=O)(=O)c1ccc2cc1CNC(=O)C(Nc1ccc3c(N)nccc3c1)c1ccc(cc1)CCCC(=O)N2 +c1ccc(CN2CCC(CCOC(c3ccccc3)c3cccs3)CC2)cc1 +O=C1NC(C(=O)O)Cc2ccc(cc2)OCCCCOc2cccc(Cl)c21 +Cc1cccc(-c2nn(Cc3cccc(C(N)=O)c3)cc2-c2ccc3ncccc3c2)n1 +CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)no2)CC1 +CS(=O)(=O)c1cccc2c(CCNCC(O)c3cccc(NS(=O)(=O)CC(F)(F)F)c3)c[nH]c12 +CC(c1ccccn1)c1c(CCN2CCCC2)sc2ccccc12 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCC3)CC2)c1)c1ccc(F)cc1 +CN(C)C1CCN(c2ccc(-n3ncc4cc(-c5ccc(Cl)cc5)ccc4c3=O)cn2)C1 +O=C(Cc1ccc(Br)cc1)NCCC(c1ccccc1)c1ccccc1 +CCOC(=O)C(C)=CC(C(C)C)N(C)C(=O)C(NC(=O)C(=Cc1ccco1)NC(C)=O)C(C)(C)C +CCCC1(C(O)CC=CC2C(O)CC(=O)C2CCCCCCC(=O)O)CCC1 +Cc1ccccc1-c1c(C(=O)N(C)Cc2ccccc2Cl)n(C)c(=O)c2ccccc12 +COc1ccccc1C1CN=C(c2ccc(OC(F)(F)F)c(Cl)c2)N1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4cnccn4)ncc23)ccn1 +O=C(CO)N1CCC(c2cc3c(-c4cncc(NCc5cccnc5)n4)ccnc3[nH]2)CC1 +O=S(=O)(c1ccc2ccccc2c1)N1CCC(c2nc(-c3ccncc3)no2)CC1 +O=C1c2ccccc2C(=O)c2oc(-c3ccccc3)nc21 +CCOc1cc(F)ccc1NS(=O)(=O)c1ccc2c(c1)CN(C(=O)Nc1ccc(C(C)(C)C)cc1)C2 +Cc1ccn2c(C)c(N(Cc3ccc(F)c(C(F)(F)F)c3)S(=O)(=O)c3ccccc3)nc2c1 +COC1C(C)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cc(C4(O)CCOCC4)cc3F)n2)CC1N +COc1cc(Cc2cnc(N)nc2N)cc(C#CCCC(=O)O)c1Br +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(OCC2CCCCN2C)n1 +CCC(C)C(N)C(=O)NS(=O)(=O)OCC1OC(c2nc(-c3ccccc3)cs2)C(O)C1O +Cn1c(=O)n(CC2CCC(NC(=O)c3cc(Cl)ccc3Cl)CC2)c2ccccc21 +COc1cc2c(cc1OC)C1C3Cc4cc(OC)c(OC)cc4C(COC(=O)CCCc4ccccc4)N3C(C#N)C(C2)N1C +O=S(=O)(c1ccc(Cl)cc1)N(C1CCNCC1)C1CC1 +NCC1CCCc2cc(S(=O)(=O)c3cc(F)cc4[nH]cnc34)ccc21 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+Cc1cccc(-c2csc(N3CC4CC4(C(=O)O)C3)n2)c1OCc1ccc2c(c1C)CCN(C1CCOCC1)CC2 +Cc1ccsc1C=CC(=O)NC(C)c1nc2scc(C)c2c(=O)o1 +CC(C)Nc1ncc2c(n1)c(NC1CC1)nc1cc(C(=O)O)ccc12 +CC1=CC(C)(C)Nc2cc3c(cc21)-c1cccc(CO)c1C3 +O=S(=O)(c1cccc(F)c1)c1cn(C2CCNC2)c2cc(Cl)ccc12 +NS(=O)(=O)c1ccc(CCN=Cc2cccc(Br)c2O)cc1 +CC(NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1)c1ccccc1 +COc1cc(C(=O)c2sc(Nc3ccc(Cl)cc3)nc2N)cc(OC)c1OC +O=[N+]([O-])C=Cc1cccc(OCc2ccc(C(F)(F)F)cc2)c1 +COc1cc(Sc2c[nH]c3ccc(Br)cc23)cc(O)c1OC +CC(NC(=O)c1cccc2c1N(Cc1ccc(C(F)(F)F)cc1)CC2)c1ccc(-c2nn[nH]n2)cc1 +c1ccc(-c2nc(NCCCn3ccnc3)cc(-c3ccncc3)n2)cc1 +COc1ccccc1N1CCN(CCC(O)c2csc3ccccc23)CC1 +O=C(NC1CCNCC1)c1c[nH]nc1NC(=O)c1c(Cl)cccc1Cl +COc1cccc2cc(-c3cc(Cl)c(C4(C)CS(=O)(=O)C5(CCOC5)C(=N)N4)s3)[nH]c12 +O=C(NC(=S)N1CCc2c(OCCCCCOc3ccc(Cl)cc3)cccc21)c1ccccc1 +Cc1cc(C(F)(F)F)cc(C2(Nc3ncc(C(=O)NO)cn3)CC2)c1 +Cc1cc(F)c(F)cc1-c1ccc(OCc2cccc3c(=O)n(CC(O)CO)[nH]c23)cc1 +CC#CCOC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +CC1(C)Oc2nc([N+](=O)[O-])cn2CC1OCc1ccc(OCc2ccccc2)cc1 +CCC(C)C=CC=CC=CC(=O)C=C(O)C1=C2C=C(CC(O)CO)C(=CNCc3ccccc3)C(=O)C2(C)OC1=O +COc1ccc2c(c1)C(=Cc1cc(C(=O)c3cc(OC)c(OC)c(OC)c3)ccc1OC)C(=O)N2 +CCOc1cc(CN2CC3(CC(N4CCC(F)(C(=O)O)CC4)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +CNCCN1CCC(OCc2cccc(C(F)(F)F)c2)CC1 +CN1C(=O)C(Cc2ccc3ccccc3c2)c2c(CCC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cccc21 +COc1ccccc1-c1cn(-c2ccc(C(=O)O)c(O)c2)cc1C#N +CNC(C)C(=O)NC(C(=O)N1CSCC1C(=O)NCC(c1ccccc1)c1ccccc1)C1CCCCC1 +Cc1oc2c(c1C(=O)c1ccc(Cl)cc1)C(=O)C(=O)c1ccccc1-2 +COc1cc2[nH]c(C)c(-c3ccc4c(c3)OCCO4)c(=O)c2cc1Cl +COc1cc(-c2ccc3ncc(C#N)c(NC4CCC(N(C)C)CC4)c3c2)cc(Cl)c1O +Cn1nnc(C2CC3(c4ccccc4)NC2CCC3OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(CC(=O)NC4CCC4)c4ccccc43)CC2)C(C)C)c1 +CCCCNC(=O)C(C)CC(O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CC(C)C)NC(C)=O +O=C(NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1)C1CC1 +CN1CCN(CC2CC3c4ccccc4Cc4ccccc4N3O2)CC1 +Nc1nc2ncc(CNc3ccc(C(=O)NC(CCC(=O)NCCCCCCCCC(=O)NO)C(=O)O)cc3)nc2c(=O)[nH]1 +O=C(Nc1cccc(Cl)c1)NC1CCN(CCOc2ccccc2-c2ccccc2)CC1 +CN1CCN(c2cc(OCc3cc(F)c(Oc4ccc(Cl)c(C(F)(F)F)c4)c(F)c3)nc(=O)n2C)CC1 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(C(=O)NCCN4CCCC4)o3)nc12 +O=S(=O)(NC1CCN(CCOc2cccc(F)c2)C1)c1cccs1 +NC(CC(=O)N1CC(CO)C(c2ccc(Cl)c(NC(=O)Cc3ccc(F)cc3)c2)C1)Cc1ccc(Cl)cc1 +CCOc1ccc(-n2cc(CCc3ccccc3)c3cc(CCC(=O)O)ccc32)cc1 +Nc1cc2n[nH]c(=O)n2c2cc(-c3ccco3)ccc12 +Fc1cc(F)cc(-c2ccc3c(c2)C2(CCCCC2)C(S)=N3)c1 +O=Cc1cn2c3c1ccc1c4ccccc4n(c13)CC(O)C2 +CC(C)(NC(=O)c1nc(-c2cccc(-c3ccc(N)nc3)c2)cnc1N)C1CCNCC1 +COCCCN(Cc1ccccc1-c1ccc(CN2CCNCC2)cc1)S(=O)(=O)c1ccc(F)cc1 +CC1=CC(C)(C)N(Cc2ccncc2)c2ccc(O)cc21 +CCOc1cnc(Nc2ccc(CCC3COC(N)=N3)cc2)nc1 +CCNC(=O)Nc1cc(-c2cccnc2)c(-c2cncc(C(=O)O)c2)cn1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1nc(C)c(C(C)NCC(C)C)s1 +O=C(CCCN1CCC(Cc2ccccc2)CC1)c1ccc(F)cc1 +CC1CCC(C(C)C)C(NC(=O)Oc2ccc(C(F)(F)F)cc2)C1 +CCN(CC)CCCN(Cc1cc2cc(OC)ccc2[nH]c1=O)C(=S)Nc1cccc(Cl)c1 +N#CCC1(COC(=O)N2CCC(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)C(C#N)C2)CC1 +Cc1cc(C#N)cc(C)c1Oc1ccc([N+](=O)[O-])c(NC2CCN(Cc3ccc(S(C)(=O)=O)cc3)CC2)c1 +CCC(NC(=O)N1CCc2cnc(NC(C)CO)nc2C1)c1ccc(OC)c(Cl)c1 +Cc1c(C#N)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1cccc(F)c1 +Nc1nc(O)c2ncn(CCCCCCC(F)(F)P(=O)(O)O)c2n1 +Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ccc(-c3ccccc3)cc1)c1ccc(C#N)cc12 +CCCCCCCNC(CNC(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1 +COc1ccc(C2=NN(c3nc(-c4ccc(Cl)cc4)cs3)C(c3ccc(O)c(OC)c3)C2)cc1 +COc1cc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)ccn1 +CC(CO)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)c2cncnc21 +COc1ccc(F)c(N2CCC(Oc3ccc(N4CC(C(F)(F)F)CC4CC(=O)O)cc3)CC2)c1 +CNC(=O)c1oc(C(C)(C)C)cc1NC(=O)Nc1ccc(C)cc1 +CCN(NC(=O)c1cc(OC)no1)C(=O)NCc1ccc(-c2cc(Cl)cc(F)c2-c2noc(C)n2)cc1F +NC(Cc1nc2c(Cl)ccc(Cl)c2nc1CP(=O)(O)O)C(=O)O +Cc1ccn(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c(=O)c1CC(=O)NCc1ccc(C(=N)N)cc1 +CSc1ncc(C2C(C(=O)OC(C)(C)C)=C(C)NC(C)=C2C(=O)OC(C)(C)C)n1Nc1ccccc1 +CN(C)c1ncnc2c1nc(O)n2Cc1cccc(NC=O)c1 +CCCCN(c1cccc(-c2ccc(Cl)cc2)c1C)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(F)c1Cl +CCCCN(CC)c1nc(C)nc2c1nnn2-c1c(C)cc(C)nc1C +O=S(=O)(Nc1nccs1)c1ccc(Oc2ccccc2-c2ccccc2)c(F)c1 +NCCn1cc(S(=O)(=O)c2cccc3ccccc23)c2cccnc21 +COc1cc(C(=O)N2CC(OC)C2)ccc1Nc1ncc2ccnc(NCC(C)(C)C)c2n1 +Oc1cccc(CNc2ccc3c(c2)CC2C4CCCCC34CCN2CC2CC2)c1 +COc1cc(NC(=O)C=CC(=O)c2c(C)c(C)cc(C)c2C)cc(OC)c1 +CC(C)n1nc(-c2cccc3[nH]ccc23)c2c(N)ncnc21 +Cn1ncc2c(Cl)cc(-c3ccc(C4(C)CCCNC4=O)c(=O)[nH]3)cc21 +COC(=O)NC(C)CNc1nccc(-c2cn(C(C)C)nc2-c2cc(C)cc(NS(C)(=O)=O)c2F)n1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(c4ccccn4)CC3)c(C(F)(F)F)c21 +CCC(CC)OC(=O)c1cn(Cc2ccccc2F)c2cc(-c3ccc(N)cc3)c(CN(C)Cc3ccccc3)n2c1=O +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4cc(Cl)ccc4n3)cc2)no1 +CC(C)(C)c1cc(C(=O)N2CCS(=O)(=O)CC2)c(NC(=O)Nc2ccc3[nH]ncc3c2)s1 +Cc1ccc(S(=O)(=O)N(CC(C)C)C(CO)CCCCNC(=O)OC2c3ccccc3-c3ccccc32)cc1 +CC1CCCN1CCc1ccc2nc(-c3cc(Br)no3)ccc2c1 +N#Cc1ccc(Cn2cncc2CN(CCCN)C2CCN(Cc3ccccc3)C2=O)cc1 +CN(CCOCCNC(=S)NC(=O)c1ccc2c(c1)C(=O)c1ccccc1-2)Cc1ccccc1 +COc1cc2c3c(c1O)C(=O)c1ccccc1C3=NCC2 +O=C(NC1CCCC1)C1CN(c2cccc(C(F)(F)F)c2)CC(=O)N1c1cccc(OC(F)(F)F)c1 +O=C(NCCCNc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1C1CC1)C1CCC1 +CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2cc(Nc3ccc(Cl)cn3)ncn2)c1 +CC(N)c1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)cc(C(F)(F)F)c1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(C)(C(F)F)Oc4ccccc43)cc21 +CCCOc1cc2oc(-c3ccccc3)cc(=O)c2c(OC)c1OCCC +CC(C)(C)c1ccc(-n2c(O)nnc2Sc2ncc([N+](=O)[O-])s2)cc1 +CCCNC(=O)c1ccc(NC(=O)N2Cc3ccc(C(N)=O)cc3C2)cc1 +NC(=O)C(Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc(O)cc(C(=O)O)c1 +NS(=O)(=O)c1cnccc1N1CCN(c2ccc(Cl)c(Cl)c2)CC1 +Clc1cnc2nc(-c3ccc(CN4CC(c5nnc(-c6ccccn6)[nH]5)C4)cc3)c(-c3ccccc3)cn12 +COc1ccc(Nc2nnc(SCc3ccncc3)[nH]2)cc1OC +Cc1cnc(Cl)nc1-c1ccc2c(c1)CCC(c1cccnc1)N2C(=O)c1ccc(O)cc1O +CC(NCCc1cc(Cl)c(NCC(=O)O)cc1Cl)C(O)c1ccc(O)cc1 +O=C(NCC1CCC(CCOc2ccccc2)CC1)c1ccc(O)nn1 +Cc1ccc(CSCCNS(=O)(=O)c2ccc([N+](=O)[O-])cc2)cc1 +Cc1cccc(NC(=O)c2c(NO)cc(-c3cccs3)oc2=O)c1 +O=C(C=Cc1c(C(=O)O)[nH]c2cccc(Cl)c12)Nc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 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+CCOC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 +Cc1ccc(C(=O)Nc2cc(N(C)CCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N(C)C)nc12 +O=C(COc1cccc(F)c1)NCC(O)CN1CCc2ccccc2C1 +Cc1c(Cl)cc2c(c1C)OC(C(F)(F)F)C(C(=O)O)=C2 +O=C(Cc1cccc2ccccc12)Nc1ccc2c(c1)ncn2Cc1ccccc1 +CCc1cc(=O)oc2cc(OCCCCN3CCC(c4noc5cc(F)ccc45)CC3)ccc12 +O=C1C(c2ccccc2)=COC12CCN(Cc1ccccc1)C2 +CC(NC(=O)C1(NC(=O)C(F)(F)F)CC1)c1ncc(-c2cc(Cl)cc(Cl)c2OCC(F)F)cc1F +CCOc1ccccc1-c1ccc(-c2nc3ccncc3c(O)c2C#N)cc1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2)CC1)C1CCC(=O)N1C(=O)C1CCCCC1 +CC(C)ON(OC1OCC(O)C(O)C1O)C1CCC2(C)C(CCC3C2CCC2(C)C(C4=CC(=O)OC4)CCC32O)C1 +CS(=O)(=O)CC(N)c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1 +CC1CC(N(C(=O)CCCC(=O)O)c2ccccc2)c2ccccc2N1C(=O)c1ccccc1 +Cc1cc(OC2CC2)ccc1N1CCC(Oc2ccc(C(C)NC(=O)c3cn[nH]c3)cc2)C1 +Cn1cc(C2=C(c3c4n(c5ccccc35)CCC(N)CC4)C(=O)NC2=O)c2ccccc21 +CCOc1cc(CN2CC3(CC(CCC(=O)O)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +CC(C)n1nc(C(=O)NC2CC3CCC(C2)N3CC(O)CN2CCC(CNS(C)(=O)=O)CC2)c2ccccc21 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+CCCCCCCN(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)C(=O)Cc1ccc(F)cc1F +COc1ccc(-c2cc3ccc(N(C)C)cc3c(N)n2)cc1OC +c1ccc(CCNc2nc(-c3ccc4[nH]ncc4c3)cs2)cc1 +CCN(CC)c1nc(NCCNC(=O)c2cc(O)c(O)c(OC)c2)c2ccccc2n1 +OCCNc1cc(N2CCc3ccccc3C2)c2ccccc2n1 +O=C(NCC1CCOCC1)c1cnc(Nc2cccc(F)c2F)nc1C(F)(F)F +COc1ccc(CCNC(C)COc2c(C)cccc2C)cc1OC +CC(=O)Nc1ccccc1-c1ccc2[nH]c(C=Cc3ccc(C(C)(C)C)cc3)nc2c1 +N#Cc1cccnc1N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +N=C(N)Nc1cccc(C(=O)NNC(=O)NC(CC(=O)O)c2ccc(Cl)cc2)c1 +CCC12CCC(=O)C(Cl)=C1c1ccc3[nH]nc(F)c3c1C2 +O=c1ccc(Cc2cc(Cc3cccc(Cl)c3)c3occc3c2)n[nH]1 +COC(=O)Nc1noc2cc(-c3c(C)n[nH]c3C)ccc12 +COc1ccc(C2(c3cc(OC)c(OC)c(OC)c3)CC(c3ccc(Cl)cc3)=NO2)cc1O +Clc1ccc2c(NCCN(CCN(Cc3ccccc3)Cc3ccccc3)CCN(Cc3ccccc3)Cc3ccccc3)ccnc2c1 +Cc1ccc(CC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1ccc2nc(N)ncc2c1 +CCCCn1c(CNc2cccc(C(=O)O)c2)nc2cc(OC)c(OC)cc2c1=O +CC(C)Oc1ccc(N=c2[nH]c(=O)n(CC3(C(=O)O)CC3)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +CCc1c(-c2cnc3ccc(N(CCNCC(F)(F)F)c4cc(OC)cc(OC)c4)cc3n2)cnn1C +COc1ccc([N+](=O)[O-])cc1CSc1nc2cc(NC(=O)NC(C)(C)C)ccc2n1Cc1cccnc1 +C=C(c1ccc(OC)cc1)c1cc(C#N)nc2ccccc12 +COc1cc(NC(=O)c2ccc(Cc3ccccc3)cc2)ccc1OCCN(C(C)C)C(C)C +CC(=O)c1cccc(Nc2nc(-c3ccccc3)cs2)c1 +CCCCN(CC)c1nc(C)nc2c1NCCN2c1ccc(OC)cc1C +Oc1cccc(-c2cccnc2Oc2ccc(Nc3ccccn3)cc2)c1 +CC(C)(C)NC(=O)c1ccc(OCC(=CF)CN)cc1 +Cc1nc(NCc2ccc(F)cc2)nc(-n2ccnc2C)c1[N+](=O)[O-] +O=[N+]([O-])c1c(Nc2cccc(Cl)c2)ccc2nonc12 +Cc1nccc(-c2ccc(F)c(C(=O)N(C)C3CCN(C)C3)c2)c1C#Cc1ccc(N)nc1 +[C-]#[N+]CC(=O)N1CCC(CCNC(=O)c2cnc(-n3ncc4cc(C#N)cnc43)cc2NC(C)C)CC1 +FCCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 +COC(=O)N1CC(C(=O)Nc2ccc(Cl)cc2)C(C(=O)Nc2ccc(-n3ccccc3=O)cc2F)C1 +COC(=O)c1c(NC(=O)C23CC4CC(CC(O)(C4)C2)C3)sc2c1CCCC2 +CS(=O)(=O)c1ccc2c(=O)n(C(CC3CCCCC3)C(=O)Nc3ncc(Cl)s3)c(=O)[nH]c2c1 +Cc1ccc(S(=O)(=O)N2CCN(c3nc(SCc4nc5ccccc5[nH]4)nc(-c4ccccc4)c3C#N)CC2)cc1 +CCC1(O)c2cc3n(c(=O)c2COC(=O)C1OC(C)=O)Cc1cc2cc(OC)ccc2nc1-3 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+O=C(NCC(c1cnc(C(F)(F)F)nc1)C1CCC(F)(F)CC1)c1cccc(Cl)c1Cl +N#Cc1cnc(C(=O)Nc2ccc(C=CC(=O)O)cc2C2=CCCCC2)[nH]1 +CC(C)N1CCC(N(C)C(=O)N2CCC(n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)C2)C1 +COc1cc(Cc2cnc(N)nc2N)cc(OCCCC(=O)O)c1OC +NC1(C(=O)O)C(OCc2cccc(F)c2F)CC2C1C2(F)C(=O)O +Cc1ccc(-c2nn(CCCCO)cc2C(=O)Nc2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)cc1 +O=[N+]([O-])c1cn2c(n1)OCC(Oc1ccc(-c3ccc(F)cc3)cn1)C2 +O=C(NCC(c1ccco1)N1CCCC1)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +N#Cc1cnc2c(NC3CC3)nc(Nc3cc(C(F)F)cc(N4CCN(C5(C#N)COC5)CC4)c3Cl)nn12 +CCCCCCCC1CC(C(=O)Nc2c(C(C)C)cccc2C(C)C)C(=O)O1 +CC1CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)CC(N)C1=NO +Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccc(N(C)C)nc3)c1)=N2 +CC(C)CN(CCCN1CCN(CCCNC(=O)c2ccc3ccccc3c2)CC1)CC(C)C +COc1ccc(N2CCN(c3ccc(C)c(C(F)(F)F)c3)C2=O)cc1OCCN1CCCCC1 +Cc1nc(-c2ccccc2C(=O)N2CC(Oc3cc(C#N)ccn3)CCC2C)no1 +O=C(CCc1nc(-c2ccc(F)cc2Cl)no1)Nc1cnc2ccccc2c1 +CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2cc(OC)c(OC)c(OC)c2)c1 +CN(C)NC(=O)Nc1cccc2c1C(=O)c1c(-c3cccs3)n[nH]c1-2 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+O=S(=O)(NCCOC12CCCCC1(S(=O)(=O)c1ccc(Cl)cc1)c1c(F)ccc(F)c1OC2)C(F)(F)F +O=C(NCC1CN(c2ccc(N3CCSCC3)c(F)c2)C(=O)O1)c1cccs1 +CC(NC(=O)c1cn[nH]c1)c1ccc(CN2CCc3c(cccc3C(F)(F)F)C2)cc1 +COC(=O)c1cc(N)c(Nc2ccc(C#N)cc2)cc1Oc1c(Br)cc(CCC#N)cc1OC +Cc1c(NC(=O)NC2CCCCC2)cccc1-c1nc(Nc2ccc(C(=O)N3CCOCC3)cc2)c2nc[nH]c2n1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1ccccc1Br +O=S(=O)(c1c(Cl)nc2sccn12)n1ccc2ncc(-c3cnn(C4CCNCC4)c3)cc21 +O=C1CCC2(O)C3Cc4ccc(O)cc4C2(CCN3CC2CC2)C1 +COc1cc(-c2ccc3ncc(C(=O)C(C)C)c(NC4CCC(N)CC4)c3c2)cc(Cl)c1O +CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +CNC1CC(c2ccc(Cl)c(Cl)c2)c2ccc(F)cc21 +CN(C)c1ccccc1C(=O)OCC1(CO)CC(=Cc2ccc([N+](=O)[O-])cc2)C(=O)O1 +O=C(Nc1ccc(-c2csc3c(=O)cc(N4CCOCC4)oc23)cc1)c1cccnc1 +COc1cc(Cl)ccc1OC(c1cccc(F)c1)C1CNCCO1 +O=C(Cc1ccccc1)NCc1cc(Br)cc2nc(O)c(O)nc12 +CC1(c2cc(NC(=O)c3cnc(-c4ccco4)cn3)ccc2F)CCSC(N)=N1 +Cc1ccsc1-c1ccc(CCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(N)=O)cc1 +c1nc(NC2CCCCC2)c2cc(-c3cncs3)ccc2n1 +COCCOc1n[nH]c2cc(NC(=O)NC(COC)c3ccc(F)cc3)ncc12 +CCN=C(NCc1ccc(Cl)cc1)SCCCc1c[nH]cn1 +CC(C)(C)OC(=O)NC(Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1C(C)(C)C +CCCCCCCCCCC#CC(O)c1ccccc1-c1ccc(Oc2ccc(OCC)cc2)c(S(=O)(=O)O)c1 +COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3OC(F)(F)F)ncnc2cc1OCCCN1CCN(C)CC1 +CCCCc1nn(CC(=O)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1cccn2c(C)c(N(Cc3ccc(F)c(C(F)(F)F)c3)S(=O)(=O)c3ccccc3)nc12 +CSc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1ccccc1C(F)(F)F +COc1ccc(N2CCc3c(-n4ccc(-n5cc[nH]c5=O)n4)cc(C)nc32)c(C)c1 +OC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +CCOc1ccc2c(c1)CCN(Cc1ccc(C(C)NC(=O)C3CC3)cc1)C2 +O=C(NCCN1CCCC1)c1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(-c3ccccc3)no2)n1 +O=c1c2cc(OCCCN3CCCCCC3)ccc2nc2n1CCCc1ccccc1-2 +COc1ccccc1N1CCN(CCCCc2cn(-c3ccc4[nH]ccc4c3)nn2)CC1 +CN(C)CC1CCC(c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)CC1 +Cc1ccc(-c2c(CN)c(CC(C)C)nc3ccc(CCC(N)=O)cc23)cc1 +Fc1ccc(C(NCC2CCN(CCc3ccccc3)CC2)c2ccc(F)cc2)cc1 +CCCCCC(O)C=CC1CCC(=O)N1CCSc1nc(C(=O)O)cs1 +NCCCc1cc2cc[nH]c(=O)c2c2cc(-c3ccc(CN)cc3)ccc12 +CCCOc1c(NC(=O)N(O)C(C)CC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC +CC1CC2OC2C=CC=CC(=O)Cc2cc(O)cc(O)c2C(=O)O1 +CN1CCC(Nc2cc(S(=O)(=O)n3ccc4ccccc43)ccc2F)CC1 +O=C(Nc1cccc(Cl)c1)ON=C1CCCCC1Cc1cccs1 +N=C(N)Nc1nc(C(CCN2CCC(c3ccccc3)CC2)C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cs1 +CN(C)CC=CC(=O)N1Cc2sc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2C1 +O=C(NCc1ccc(S(=O)(=O)c2ccccc2)cc1)c1nc2ccncc2s1 +Brc1ccc(-c2nnc3sc(CN4CCN(c5ccccc5)CC4)cn23)cc1 +O=C(NC1CCCC1Nc1cnc(C(F)(F)F)cn1)c1ccccc1-n1ccnn1 +CC(O)C(N)C(=O)NS(=O)(=O)c1cccc(-c2ccc3c(N)ncnc3c2)c1 +CN1C(=O)C(C)(C)C(C)(c2cc(Nc3cccc(C#N)c3)ccc2F)N=C1N +CCC(Nc1nc2c(c(=O)n1OC)CN(C(=O)c1ccc(C#N)cc1F)CC2)c1ccc(C(F)(F)F)cc1 +COc1ccc2[nH]c(C(=O)c3cc4ccc(Cl)cc4[nH]3)cc2c1 +CCC(c1cc(C)no1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COc1ccc(-c2cc3c(C)nc(N)cc3n(C3CCCC3)c2=O)cn1 +COc1ccc2cc(C(=O)Nc3ncc(Cc4cccc(C(F)(F)F)c4)s3)ccc2c1 +O=C(NCc1ccc(Br)cc1)OCc1cn(-c2cc3nc(C(=O)O)c(O)nc3cc2[N+](=O)[O-])cn1 +Cn1cccc1C(=O)NCc1cc(Br)cc2nc(O)c(O)nc12 +CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC1(CC2)CC1 +Clc1ccc(-c2ccc(-c3nccn3-c3ccc(N4CCNCC4)cc3)o2)cc1 +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)N4CCN(C)CC4)c4cc(Cl)c(C)cc34)cc2)c1C +CS(=O)(=O)c1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)cc1 +O=C(CCCCC#Cc1ccccn1)c1ncc(-c2ccccn2)o1 +CC(Sc1nc(-c2ccc(Cl)c(F)c2)c(C#N)c(=O)[nH]1)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CC1=CC(=O)N(Cc2ccc(C#N)cc2)S(=O)(=O)O1 +O=C1c2cccc3cccc(c23)C(=O)N1CCCNCCCCCCCCNCCCN1C(=O)c2cccc3cccc(c23)C1=O +COCC12CNCCC1(c1ccc(C(F)(F)F)c(Cl)c1)C2 +Fc1ccn(Cc2cccc3c2CCC3c2ncc[nH]2)n1 +Cc1ccc(S(=O)(=O)c2cc3cnc(Nc4ccc5[nH]ccc5c4)nc3n(C)c2=O)cc1 +CCC(NC(=O)C(NC(=O)C(CCCc1ccccc1)CC(=O)O)C(C)(C)C)c1ccccc1 +COc1cc(CCc2nc3c(OC)ccc(C)n3n2)nc2ccccc12 +CCN(CCO)Cc1csc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)n1 +[H]C([H])([H])NCCC(Oc1ccccc1OC)c1ccccc1 +CCc1nnc2n1C1CCN(C(=O)CC(N)Cc3cc(F)c(F)cc3F)CC1CC2 +O=C(CC1(C2COC3CCCC3N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC(O)C1 +c1cc2oc(N3CCN4CCC3CC4)nc2nc1C1CCCC1 +CCN(CC)CCNC(=O)Cc1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +CCS(=O)(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3CC4)cc2)cc1 +COCCN(CC1CCCN(C2Cc3ccccc3C2)C1)C(=O)c1ccc2ccccc2c1 +Cc1c(-c2nnc(C(C)(C)C)o2)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)c1nnn(-c2ccccc2)c1C(F)(F)F +CCCOC(=O)Oc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +Cc1cc(S(=O)(=O)Nc2ccc3c(c2)CCN(C)CC3)ccc1-c1ccc(Cl)cc1 +O=C(c1ccc(F)c(Cl)c1)N1CCC(F)(CNCc2ccc(CO)cn2)CC1 +Cc1ccc(C(CCNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(F)cc2)cc1 +CN(C)Cc1ccc(-c2ccc3ccn(C(N)=O)c3n2)cc1 +Cc1cccc(C)c1C(=O)NCc1ccc(-c2cc[nH]c(=O)c2)cc1 +Cn1cc(-c2ccncc2)c(-c2ccc(OCc3nc4ccccn4n3)cc2)n1 +COc1cc(O)cc(C=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c1 +CN(C)CCn1cc2c3c(cccc31)C1=CC(C(=O)N3CCCC3)CN(C(=O)Nc3ccccc3)C1C2 +N=C(N)c1ccc(OC(=O)c2ccc(CC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)O)o2)cc1 +N#Cc1cc(F)cc(-c2ccc3nc(O)n(-c4ccccc4)c3c2)c1 +CCN(CC)C1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nc2)CC1 +COC(=O)CN1CC(Nc2nc3cc(C)ccc3[nH]2)C(OC(=O)c2ccc(-c3ccccc3)cc2)C1 +CCCC1OC(O)=C2C1=NC1=C(C(=O)COC1)C2c1ccc(Br)c(Cl)c1 +Cc1cnc(-c2cccc(Cn3nc(-c4cc(F)cc(F)c4)ccc3=O)c2)nc1 +Cn1cnc(-c2ccnc(Nc3cc(Cl)c4[nH]c(C(=O)NCC5CCOCC5)cc4c3)n2)c1 +C1=CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +CCCCc1nc(C(F)(F)c2ccc(-c3ccccc3-c3nn[nH]n3)cc2)n(CCCC)n1 +CN(C(=S)Cc1cccc2sccc12)C1CCCCC1N1CCCC1 +COc1cccc(Nc2nc3cc(C(=O)O)ccc3c3scnc23)c1 +COc1ccccc1-c1c[nH]c2ncnc(N3CCC(F)C3)c12 +CNC(=O)C1Cc2ccccc2N1C(=O)COc1ccccc1 +CCc1cccc(NC(=O)N2CCc3nc(-c4cccnc4)nc(-c4c(Cl)cccc4Cl)c3C2)c1 +CC(C)N(C(=O)OC1CN2CCC1CC2)c1ccccc1 +O=C(Cc1ccc(OCc2ccccc2)cc1)N(O)CCc1ccccc1 +O=C1NC(=O)c2c1c1c3ccc(C(F)(F)F)c(CO)c3[nH]c1c1c2c2cccc3c2n1CCNC3 +COc1cccc2nc(C)c3nnc(-c4ccccc4Cl)n3c12 +CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1Oc1ccccc1CC(=O)O +CCOC(=O)c1c(C)nc(Nc2ccc3nc(C)sc3c2)n(Cc2ccc(Cl)cc2)c1=O +NC(=O)n1cc(NC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2cc(OCCN3CCCC3)ccc21 +Cn1c(=O)c2c(nc(N3CCCC(N)C3)n2Cc2ccccc2Cl)c2cc(CC(=O)O)ccc21 +CC1CCC(=O)N1c1ccc2cc(NC(=O)C3CC3F)ncc2c1 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2cc(C#N)cn2)n1 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+C=CCN(C(=O)c1ccc2c(c1)nc(NC(=O)c1ccccc1)n2CCC(N)=O)C1CCCCC1 +COc1cc(-c2cnc(N)c3c(-c4cccc(Cl)c4Cl)csc23)cc(OC)c1OC +Cc1c(-c2ccnc(N)n2)sc2ccc(C(N)C(C)C)cc12 +O=C(c1ccccc1)C1CCN(C2Cc3ccccc3CC2O)CC1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ncc(-n5cnnn5)cc4OC)CC3CO2)c1C +CCCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1nc(C)c(Br)c(=O)[nH]1 +NC(=O)n1cc(NC(=O)N2C(C(=O)NCc3ccccc3F)CC3CC32)c2cc(OCC(=O)O)ccc21 +Cn1c([N+](=O)[O-])cnc1C=Cc1ccc(Cl)cc1 +O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3C2C1 +COc1c(Cl)cc(Cl)c(O)c1C(=O)NCC1CCCN1Cc1ccc(F)cc1 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCCOc3ccccc32)n1 +CCCN(CCCCNc1ccnc2cc(Cl)ccc12)Cc1ccc(C)o1 +Cn1ncc(-c2ccncc2)c1-c1ccc(OCc2cc(OCCOCCF)c3ccccc3n2)cc1 +Fc1cc2nc(SCC3CCCCC3)[nH]c2cc1N1CCNCC1 +CCC(CS(=O)(=O)c1ccccc1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COC1CCN(c2nc(NC3CCCNC3)c(-c3ccc4ccccc4n3)c(=O)[nH]2)C1 +CC[n+]1c(C=C2Sc3oc4ccccc4c3N2C)ccc2cc(C)ccc21 +CC(=O)N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +O=C(NCCO)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 +CCOC(=O)c1nnn(-c2ccc([N+](=O)[O-])cc2)c1C(O)C(O)C(C)O +CC(NC(=O)C1=C(O)C(=O)N(C)C1)c1cccc(-c2cccc(F)c2)c1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)C(CO)c3ccc(Cl)cc3)c2)c2cncnc21 +O=C(CN1CC(O)C(NC(=O)c2ccc(Cl)s2)C1)Nc1ccc(-n2ccccc2=O)cc1F +Cn1cc(-c2cc(Cl)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +O=C(CC1CCCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1)NC1CCCc2cc(CNC3CC3)ccc21 +COC(=O)Nc1cc2c(c(N)n1)N=C(c1ccccc1)C(C)N2 +Cc1cc(C)cc(Nc2nccc(-n3cc(CN4CCC(O)CC4)c(C)n3)n2)c1 +CC12CCC3c4ccc(OS(N)(=O)=O)cc4CCC3C1CC(=O)N(CCC(F)(F)F)C2=O +N#CCOc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +Oc1ccc2c3c1OC1Cc4c([nH]c5ccccc45)C4C(C2)N(CC2CC2)CCC314 +Cc1nn(Cc2ccc(-c3nc4cc(Br)ccc4[nH]3)cc2)c(C)c1CC(=O)O +O=C(CN1C(=O)N(CC(=O)N2CCCC2)c2ccccc2N(c2ccccc2)C1=O)Nc1cccc(C(=O)O)c1 +CC1=CCC2C(C1)c1c(O)cc(C(C)(C)CCCCC(=O)Nc3ccc(S(N)(=O)=O)cc3)cc1OC2(C)C +CC(=CC(C(C)C)N(C)C(=O)C(NC(=O)C(N)C(C)(C)c1ccccc1C)C(C)(C)C)C(=O)O +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ncccn2)CC1c1ccc(F)cc1F +CNC(=O)c1cnn(-c2nc(N)c3ncn(C4OC(CO)C(O)C4O)c3n2)c1 +O=C(CC1CCCO1)NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1 +Cc1ccc(C(=NNC(N)=S)c2cccc(C(F)(F)F)c2)cc1 +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Br)o1)Oc1ccccc1-3 +COc1ccc(CC(Sc2ccc(OCC(=O)O)c(C)c2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1 +O=C(O)CCCC(=O)N1N=C(c2c(-c3ccc(Cl)cc3)c3ccccc3[nH]c2=O)CC1c1ccc(Cl)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccc[n+]([O-])c4)ncc23)ccn1 +Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 +COc1cc(-c2cccc(Cl)c2F)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CCC(CC)(NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC +CC(C)c1cc(Nc2nc(Nc3ccc(N4CCOCC4)cc3)ncc2Br)[nH]n1 +CC(C)n1nc(Cn2nc3ccccc3c2OCCCCO)c2ccccc21 +CCCC#Cc1ccc(-c2c(CC)c(C(=O)NN3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 +O=C1C(c2ccc3ccccc3c2)C(c2ccc(O)cc2)N1c1ccc(O)cc1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)C(C)(C)C(=O)CC2 +CC(C)Oc1ccc(S(=O)(=O)N2CCN(c3ccc(Br)c(OCC(=O)O)n3)CC2)cc1 +O=C(OC1CCCN(Cc2ccccc2)C1)C(O)(c1ccccc1)c1ccccc1 +Cc1c(Nc2c(C#N)cncc2C=CCCCN2CCCCC2)ccc2[nH]ccc12 +CN1CCc2c([nH]c3ccccc23)CC(c2ccccc2)CC1 +O=C(C1CCOCC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +COc1cc(-c2ccc3oc(N4Cc5ccccc5C4)nc3c2)ccn1 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1ccc(F)cc1 +O=C(c1nn(C2CCCN(CCN3CCCC3)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CCn1cc(C(=O)C2CC2)c2cc(Nc3ncc(F)c(-n4cc(CN5CC(O)CO5)c(C)n4)n3)ccc21 +Cc1nc(CN2CCC(COCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)(c3ccccc3)CC2)cs1 +CCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +CCOC(=O)N1CC2CCC(C1)C2NCCNC(=O)c1cccc(Cl)c1 +CCCCn1cc2c(nc(NC(=O)Nc3cccc(OC)c3)n3nc(-c4ccco4)nc23)n1 +CCCCCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(SC3CCCCC3)nc(-c3ccccc3)n2)CC1 +CN1CCc2nc(C(=O)NC3CC(C(=O)N(C)C)CCC3NC(=O)c3[nH]c4ccc(Cl)cc4c3Br)sc2C1 +CC1(C)N2Cc3ccccc3CC2C(=O)N1C(Cc1ccc(O)cc1)C(=O)O +CN1C2CCC1CC(OC(c1ccccc1)c1ccc(C(F)(F)F)cc1)C2 +CCOc1ccccc1C=CS(=O)(=O)Nc1ccccc1S(N)(=O)=O +CCOC(=O)N1CCN(CCOc2ccc(-n3ccnc3)cc2)CC1 +CC[n+]1c(C=Cc2ccc(N(C)C)cc2)sc2cc(NC(C)=O)ccc21 +O=C(Nc1ccc(C(=O)O)c(F)c1)c1ccc2c(c1)N(S(=O)(=O)c1cccc(C(F)(F)F)c1)CC2 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+Cc1nc(-c2c(F)cccc2-c2ccc(C(C)Nc3nccc(Cl)c3NC(=O)CC#N)cc2)no1 +CNc1nccc2c(OC(C)C(=O)N3CCN(C(=O)c4ccccc4)CC3C)cccc12 +COc1ncnc(NCc2ccc(S(N)(=O)=O)cc2)c1[N+](=O)[O-] +Oc1nc2ncc(-c3cnc(N4CCOCC4)c4nc(C=Cc5ccc6ccccc6n5)cn34)cc2[nH]1 +COc1ccc(C(=O)N2CCN(c3ccncn3)CC2)cc1C#Cc1cccc(Cl)c1 +O=C1NC(=O)c2c1c(-c1ccccc1)cc1c2c2cc(O)ccc2n1CCCNc1ccccc1 +COc1cc(OCc2cccc(OCc3ccccc3OC(F)(F)F)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CNC(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1 +N#Cc1c(NCCCNCc2cc(Br)cc(Br)c2)[nH]c2ccccc12 +O=C(Cc1ccc(O)c(Br)c1)NN=C1C(=O)Nc2ccccc21 +CC(=O)N1CC(N2CCC(c3cc(C#N)cc(Nc4nc(NC5CC5)c5ncc(C#N)n5n4)c3Cl)CC2)C1 +CC(C)CC(NC(=O)COc1cccc(N(C)C)c1)C(=O)NC(CC1CCNC1=O)C(=O)c1nc2ccccc2s1 +CCOC(=O)C1=C(CN2CCOCC2)NC(n2cncn2)=NC1c1ccc(F)cc1Br +CC1CC2C3CCC4N(C)C(=O)C=CC4(C)C3CCC2(C)C1O +O=C(NCCCCCCCn1cc(-c2cccnc2)nn1)Nc1ccccc1-c1ccccc1 +c1ccc(CNC2C3CC4CCC(C3)N4C2C(c2ccccc2)c2ccccc2)cc1 +CCCCn1cc2c(nc(N)n3nc(-c4ccco4)nc23)n1 +Fc1ccc(C(c2ccc(F)cc2)C2CCN(CCOc3cccc4ccccc34)CC2)cc1 +COc1cccc2c1c(C(=O)C=C(O)C(=O)O)cn2Cc1cccc(Cl)c1F +COc1ccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)cn1 +CN1CCc2cc(Cl)c(O)cc2C(c2ccc(CN(C)S(C)(=O)=O)cc2)C1 +COC(=O)Nc1ccc2c(c1)NC(=O)C(C)CCCC(N1CCC(c3cc(C)ccc3F)=CC1=O)c1cc-2ccn1 +CCCCNC(=O)NCCc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +O=c1cc(Nc2cccc(C(F)(F)F)c2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 +CC(Oc1cc(C(=O)NC(c2nnn(C)n2)C(C)(C)C)ncc1C1CC1)C(F)(F)F +Cc1c(N=C(N)c2ccccn2)ccc(-c2ccc(-c3ccc(N=C(N)c4ccccn4)c(C)c3C)o2)c1C +CNC1CCN(c2nc(N)nc3c2CCCC32CCCC2)C1 +CC(=O)N1CCn2cc(C3=C(c4cccc5c4OCO5)C(=O)NC3=O)c3cccc(c32)C1 +Nc1nc(N)c2c(OCC3CCN(CC(F)(F)F)CC3)cccc2n1 +COC(=O)C(C)(C)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 +CCCCC(CN(O)C=O)C(=O)NC(Cc1ccc(Cl)cc1)C(=O)N(C)C +COc1ccc2cc(C(C)Nc3nccc(N4C(=O)OCC4(C)C)n3)ccc2c1 +O=C(NC1CCCCC1)N1CCN(C(c2ccc(Oc3ccccc3)cc2)c2ccc(Cl)cc2Cl)CC1 +CC(C)(C)OC(=O)c1ncn2c1CN(C(=O)N1CCNCC1)c1ccccc1-2 +COc1cc2ncnc(Nc3ccc(B(O)O)cc3)c2cc1OC +O=C(NCCN1CC2CC(n3c(=O)[nH]c4ccccc43)CC2C1)c1ccc(Br)cc1 +O=C(C=Cc1ccccc1)OC1C2OC(=O)CC2OC1C(O)c1ccccc1 +O=S(=O)(NC1CCNC1)c1ccc2[nH]c(-c3cc4ccccc4nc3O)cc2c1 +COc1c(C(=O)C=Cc2cc(Br)cs2)c(O)c(OC)c2occc12 +Cc1ccc(C(=O)NC(C)C(N)=O)cc1-n1cnc(OCc2ccc(F)cc2F)c(Cl)c1=O +CCCc1cc(F)c(N)c2nc(-c3ccc(P(=O)(O)O)o3)n(CC(C)C)c12 +Cc1c(COC(=O)NC(C)C)c(COC(=O)NC(C)C)c2n1Cc1c(c3ccccc3n1Cc1ccccc1)C2 +CC(=O)c1cc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3)C2)cc(-c2nnnn2C)c1 +Cc1cccc(C(=O)NC2CC(n3cnc4c(NCC5CCCCC5)ncnc43)C2)n1 +Cc1ccccc1C(=O)c1csc(NCCCNS(=O)(=O)c2cccc(F)c2)n1 +Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3c(C)cccc32)cc1 +Oc1ccc(Br)c(C(Nc2ccccn2)c2ccc3cccnc3c2O)c1 +CCOc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2cccc(C(F)(F)F)c2)CC1 +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)COc1ccc2[nH]c(=O)c(S(C)(=O)=O)c(CCc3ccccc3)c2c1 +CC(C)(C)OC(=O)N1CCC(C2CCN(c3ccc(S(C)(=O)=O)cc3)CC2)CC1 +c1ccc2oc(-c3ccc(OCCCCNc4c5c(nc6ccccc46)CCCC5)cc3)nc2c1 +CC1CN(C)C2(CCCC2)CN1C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C +COc1ccc2c(OCc3nnc4ccc(-c5cc(F)c(F)c(F)c5)nn34)ccnc2c1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(Oc2ccc(Br)c(OCC(=O)O)c2)cc1)Cc1ccc(F)cc1F +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)c1Cl +O=C(c1ccc(Cl)cc1)c1ccc(OC2CN3CCC2CC3)cc1 +Cc1cccc2nc(-c3c(NC4CCCNC4)nc(N4CCOCC4)[nH]c3=O)sc12 +CC(=O)N1c2ccc(-c3ccc(C(=O)O)cc3)cc2C(Nc2ccc(C)cc2)CC1C +C[N+](C)([O-])CCNc1ccc2ncn3c4ccc(F)cc4c(=O)c1c23 +CC(C)(C)c1ccc(-c2ccc(Cl)cc2)cc1NC(=O)C1CCC2C3CNC4=CC(=O)CCC4(C)C3CCC12C +COc1cccc(NC(=O)c2ccc(C)c(Nc3nc4ccccc4n3-c3cc(N)ncn3)c2)c1 +CCC(=C(c1ccccc1)c1ccc(C=CC(=O)N2CCOCC2)cc1)c1ccccc1 +Cc1c(NS(=O)(=O)c2ccc(-c3ccccc3CN(C)C)cc2)c(CC(C)C)nn1C +Cc1cc(NC(=O)c2ccc(C#N)cn2)cc(C2(C(F)F)N=C(N)OC3CC32)c1F +CN(C)CCOc1ccc(C(=C(CCCN=[N+]=[N-])c2ccccc2)c2ccc(O)cc2)cc1 +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OC6CCOc7ccccc76)ccn5)n4)ccc3[nH]2)CC1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3cccs3)ccc21 +COc1cccc(C(=O)NC2(C(=O)NC(Cc3ccccc3)C(=O)NCC3CCN(CC4CCOCC4)CC3)CCCC2)c1 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+CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(Br)c1 +COc1cc(-c2ccc(Cl)c(C)c2)c(C)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CN1CCC(Cc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3n2)CC1 +CCC(N)C(=O)NC1C(=O)N2C(CCC1COC(C)=O)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +COc1ccc(Nc2ncc3c(n2)-c2ccc(C#N)cc2NC(=O)C3)cc1OC +O=S(=O)(NCCN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1)c1ccccc1 +O=S(=O)(c1ccccc1F)C1(F)CCN(CCc2ccc(F)cc2F)CC1 +Cc1ccc(-c2nc(CCCCC3COC(C)(C(=O)O)OC3)c(C)o2)c(C)c1 +O=C(C=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)Nc1ccc(F)cc1[N+](=O)[O-] +O=C(O)C(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C1OCOC1C(=O)Nc1ccccc1F +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc3c(c2)CCN3C)cc1 +CCCc1c(OCCCCOc2ccc(C(=O)O)cc2)ccc2c(-c3ccccc3)noc12 +Oc1cccc(-c2cc(NCc3cccnc3)nc(N3CCOCC3)n2)c1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccccc3)o2)C(C)O)c(C)c1Cl +Cc1c(NC(=O)C(C)Br)cccc1C(=O)NC(N)=O +C=COC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)CCCCNC(=O)OCc1ccccc1)C(C)C +Cc1cccc(-c2cc(NCCN3CCOCC3)c3ccccc3n2)c1 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+CCCC(NC1CCc2ccccc2N(CC(=O)O)C1=O)C(=O)O +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(C)NC3CCCC3)c2=O)c1F +CNc1nnc(-c2cn3ncnc(Nc4cnc5[nH]c(C)cc5c4)c3c2C(C)C)o1 +C=C1C=C(C)CC(C)(C)C1Cc1cc(OC)c(Br)cc1O +COc1ccc(C(=O)C(Cc2cccc(OC)c2)=C(C(=O)O)c2ccc3c(c2)OCO3)cc1 +COc1ccc(C(=O)c2ccc(=O)n(-c3cccc(C)c3)c2)c(O)c1 +CCC(C)C(N)CN(C(=O)C1CC1c1cccc(F)c1)c1ccc(-c2ccccc2)cc1 +Cc1ccc(Nc2nc(C(=O)N3CCC(C)CC3)cs2)cc1 +Cc1cccc(-c2nc(NCc3cccc(C#N)c3)sc2-c2ccc3ncnn3c2)n1 +CCOC(=O)c1sc2nc(CC(=O)NNC(=S)Nc3ccccc3)[nH]c(=O)c2c1C +O=C(CN1CCC(N2C(=O)OCc3cc(Cl)ccc32)CC1)Nc1ccc(C(=O)c2ccccc2)cc1 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)c3ccc(OC(C)C)cc3)cc12 +CC(C)c1onc(COc2ccc(Cl)cc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)Nc3ccccc3F)nc12 +CNCCN1CCC(OCc2ccc(C(F)(F)F)cc2)CC1 +CCN(CC)c1nc2ccc(NC(=O)c3c(C(=O)N4CCC4)cnn3C)cn2n1 +Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1cccc([N+](=O)[O-])c1 +COc1cc(-c2cn(CC(=O)N3CCC(c4nc5ccccc5o4)CC3)nn2)ccc1-n1cnc(C)c1 +COc1ccccc1-c1csc(Nc2ccc(Oc3ccccc3)cc2)n1 +O=C(Cc1ccccn1)N1CCc2nc(-c3cc4ccccc4[nH]c3=O)[nH]c2C1 +CCCN(CCCON1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1 +C=CC1(C)CCC(C2=CCC(C(C)(C)O)OC2)CC1C(=C)C +O=C(O)CN1C(=O)C(=Cc2ccc(OCCc3ccc(OC(F)(F)F)cc3)c(OCc3ccccc3)c2)SC1=S +CC(C)(C)n1c(-c2ccccc2C(=O)NC2CCNCC2)nc2cc(-c3cnc(N)nc3)ccc21 +CNC(=O)NC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc21 +CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C(=O)N1CCS(=O)(=O)CC1 +O=C(O)CCN1CC=C(c2ccc(OCCCc3ccccc3)cc2)CC1 +CCc1ccc(NC(=O)N2CC(CC#N)(n3cc(C(N)=O)c(Nc4ccccc4)n3)C2)cc1 +Clc1ccc(-c2nn(Cc3ccccc3)nc2-c2ccc(Cl)cc2Cl)cc1 +CCCCc1ccc(-n2[nH]c3c(cnc4ccccc43)c2=O)s1 +NC(C(=O)NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(C2(CNC(=O)Cc3ccccc3)CCCCC2)CC1)c1ccccc1 +O=C(c1ccc(Br)cc1NS(=O)(=O)c1cccc2nccnc12)N1CCOCC1 +O=C(c1nn(C2CCC(O)CC2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +O=C(Nc1cccc2c1C(=O)c1c(-c3ccc(C(=O)NCCN4CCCCC4)s3)n[nH]c1-2)NN1CCOCC1 +Cc1ncc(C(CNC(=O)c2cccc(OC(F)(F)F)c2Cl)N2CCC(F)(F)CC2)cn1 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+O=C(O)CCCCCCN1C(=O)CCC1C=CC(O)c1cccc(-c2cccc(Cl)c2)c1 +O=[N+]([O-])c1cc2c(O)c(-c3cc(F)cc(F)c3)c(O)nc2cc1Cl +O=C1c2ccc(-c3ccc(C(F)(F)F)cc3)cc2CCN1CCN1CCCC1 +CCOC(CO)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +COc1cc(-c2cn(C3CC(C(C)(C)C)CCN(CC(C)(C)C)C3=O)nn2)ccc1-n1cnc(C)c1 +Cc1cccc(-c2nn(C(=S)Nc3ccccc3)cc2-c2ccc3nc(C)nn3c2)n1 +COc1ccc(-c2ccc(CN(CCC3CCN(Cc4ccc(C)cc4)CC3)C(=O)NC(C)(C)CO)cc2)cc1 +Cc1cc(Nc2cc(C(F)(F)F)c(Cl)cn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1 +CC(=O)Nc1cccc(Nc2cc(NC3CC3)n3ncc(C#N)c3n2)c1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(N3CC4(CCOC4)C3)c2n1 +COC(=O)CN(c1ccc2nc(C)n(Cc3ccc4ccc(C(=N)N)cc4c3)c2c1)C1CCN(C(C)=N)CC1 +COc1ccc(-n2nnc(-c3ccc(S(=O)(=O)NC(Cc4c[nH]c5ccccc45)C(=O)O)cc3)n2)cc1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)nc3[nH]ccc23)c1 +CC1CCCCN1CCCNc1ncc(C(=O)NCc2ccccc2)c(NC2CCCC2)n1 +O=c1c2ccccc2nc(C=C(O)c2ccccn2)n1-c1ccccc1Cl +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)NCCC3CCCN3C)sc2c1 +COc1ccc(CC(CN(O)C=O)C(=O)NC(C(=O)N(C)C)C(C)(C)C)cc1 +N=C(N)c1ccc(CNC(=O)C2C=CCN2C(=O)C(CC2CCCCC2)NCC(=O)O)cn1 +O=C(Nc1ccc(-c2ccccc2)cc1)c1cc(I)cc(I)c1O +O=S(=O)(Nc1ccccc1)c1ccc(-c2nccnc2Cc2ccccc2)cc1 +Cc1cc(-n2cnc3c(NCC4CCOCC4)cc(Oc4cccc(F)c4)cc32)ccc1C(=O)NC1CC1 +Clc1cncc(Cl)c1NN=Cc1ccccc1-c1c(Cl)cccc1Cl +CC(=O)OCC12CCC(=O)C=C1C1(C)C=C(C#N)C(=O)C(C)(C)C1CC2 +CC(NCC(O)C(Cc1ccccc1)NC(=O)c1ccc(N2CCN(C)CC2)cc1)c1ccc(O)c(CN2CCCCC2)c1 +O=C(O)C1CN(CCNc2nc3ccccc3n(C3CC4CCC(C3)N4C3CCCCCCC3)c2=O)CC1C(=O)O +CCCCOc1nc2c(c(Nc3ccc(C(F)(F)F)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)NO)[nH]c2cc(Cl)ccc12)C(=O)NO +O=c1cc(C2CCCCC2)oc2ccc(OCCCCCCN3CCCCC3)cc12 +Cc1cccc(NC(=O)c2nc(C)ccc2Nc2cccnc2)n1 +COc1cc(C(=O)NC2(C(=O)NC(C)c3ccc(-n4[nH]c(=O)c5ccccc54)cc3F)CC2)on1 +CC(=O)c1ccc(-c2cnc(N)nc2-c2c[nH]c3ccc(Br)cc23)cc1 +NS(=O)(=O)c1c(F)c(F)c(SCCc2ccccc2)c(F)c1NC1CCCCCCCCCCC1 +NC(=O)COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2 +COc1ccc(CN2C(=O)CNC(c3ccccc3F)(C(Oc3nc(C)cc(C)n3)C(=O)O)c3ccccc32)cc1 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+CCCC(C)CNC(=O)c1ccc2c(c1)c(Cc1ccc(C(=O)NS(=O)(=O)c3ccccc3C)cc1OC)cn2C +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc5ccccc5[nH]4)cc3)cc2)C(=O)NC(=O)NC1=O +O=C(Nc1cc(-c2cc3c([nH]2)C2(CCCNC2)CNC3=O)ccn1)c1ccc2ccccc2c1 +CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)NC(=O)C(NC(C)=O)CC3(C)C)ncc1Cl +CC(C(c1ccc2cc(OCc3ccc(OCC(=O)O)cc3)ccc2c1)n1ccnc1)N(C)C +CCCn1c(=O)c2nc(C3Cc4ccccc4C3)[nH]c2n(CCC)c1=O +CCc1ccc2[nH]cc(C(=O)CCC(C)(C)C)c(=O)c2c1 +O=c1c2ccccc2sn1-c1ccc(S(=O)(=O)N2CCOCC2)cc1 +CC(C)(O)CN1CCC(N(c2ccc(C#N)cc2)c2cccnc2)CC1 +CC(C)(C)NC(=O)NC1CCC(CCN2CCc3ccccc3C2)CC1 +CCCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(F)ccc(C(=O)NC)c2C1 +O=C(NCCOCCO)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +C=CC(=O)Nc1cccc(-n2c(-c3nc(-c4cnn(C)c4)cnc3N)nc3ccccc32)c1 +CC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccoc3C)n2Cc2ccco2)cc1 +CCc1ccc(-c2nc(CCOc3ccc4c(c3)CCC4C(CC)C(=O)O)c(C)o2)cc1 +O=C1C(=Cc2ccc(OCCN3CCCC3)c(Cl)c2)Oc2cc(O)ccc21 +COCC(C)Oc1cc(C=Cc2ccccc2OC)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 +CN1CCN(c2ccc(-c3cccc(OCC(O)CN4CCc5ccccc5C4)c3)cn2)CC1 +Cc1sc2nc(Cc3cccc(C(F)(F)F)c3F)cc(=O)n2c1C1CC1CO +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ncc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F +C=C1C(=O)C23C4OC(C)(C)OC25OCC2(C(=O)C=CC(C)(C)C2C5O)C3CCC14 +O=C(c1ccc(F)cc1)N1CCN2C(=O)c3ccncc3C12c1ccc(Cl)cc1 +O=C(NCC1CN(c2ccc(N3CCCC3=O)c(F)c2)C(=O)O1)c1ccc(Cl)s1 +COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccc(F)cc2)CC1 +CNC(=O)c1nn(C)cc1NC(=O)c1nc(C2CC2)ncc1Nc1cncnc1 +COc1cc(NCCN2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)C)n1)CCN2 +COc1c(-c2cn[nH]c2)ccc(C(=O)NC(CO)c2c(F)cccc2F)c1F +O=C(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1cc2ccccc2n1Cc1cc(Cl)ccc1Cl +Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4nnnn4-5)CC3)cccc2n1 +CCCCCCOCCCCCCCCCc1cc2cn(C3CCC(CO)O3)c(=O)nc2o1 +Cc1cccnc1-c1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(C(=O)Nc2nc(CN3CCOCC3)cs2)c1 +CC(C)c1csc(NC(=O)C2c3ccccc3Oc3ccccc32)n1 +CC(C)Cc1ccc(C(C)C(=O)NCCOc2ccc3ccc(=O)oc3c2)cc1 +O=C(NC(c1ccccc1)c1ccccc1)c1cc(-c2ccccc2)nc2ccccc12 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(S(N)(=O)=O)cc3Cl)CC2)ncc1Br +CC(NC(=O)c1ccc(C#Cc2cccc(F)c2)cn1)C(C)(C)F +CCCCN(CCCc1ccc(O)c(OC)c1)C(S)=NCCc1ccccc1 +Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CC(N(C)CCC(F)(F)F)C1 +NS(=O)(=O)c1ccc(F)cc1NS(=O)(=O)C=Cc1ccc(Br)cc1 +Cn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(C(F)(F)F)c2)CC3)cn1 +CCc1nc(C2CC2)nc2c1CN(c1ncnn3c(C)nc(-c4ccccc4F)c13)CC2 +Cc1cc(C)nc(N2CC3CCN(C(=O)c4c(F)cccc4-n4nccn4)CC32)n1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ncc(F)cc3F)cs2)CO1 +CCCCCc1ccc(C#CC(O)(c2ccc(C#N)c(-c3cccc4ccccc34)c2)c2cncn2C)cc1 +Cc1c(CC(=O)O)c2ccsc2n1Cc1ccc(S(=O)(=O)N2CCOCC2)cc1 +CCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)ncn3Cc2ccccc2)cc1 +Cc1cccc2c1N(CC1CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC1)C(=O)C2(C)C +COCCCOc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc3C)CC2)ncn1 +CC1(C)N=C(N)N=C(N)N1OCCCCOc1cccc(C(=O)C=Cc2ccccc2)c1 +Cn1c(=O)cc(Nc2ccc(F)cc2F)c2cnn(-c3ccc(F)cc3F)c21 +CN1CCC(OC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 +COc1ccc(NS(=O)(=O)c2ccc3c(c2)c2cc([N+](=O)[O-])ccc2n3C)c(OC)n1 +O=C(O)CCc1ccccc1C(=O)N1C(=O)CCC1c1nc(C(=O)NCCCCC2CCCCC2)co1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)nc3cc(CN(C)CCCN(C)C)ccn23)n1)c1ccccc1 +NC(=O)Nc1ccc2c(c1)C(=Cc1cc(C(=O)O)c[nH]1)C(=O)N2 +CCc1cn(C2CC(O)C(CNC(=O)Cc3ccccc3Cl)O2)c(=O)[nH]c1=O +Cc1ccc(NC(=O)CSc2snnc2-c2ccc(Br)cc2Br)c([N+](=O)[O-])c1 +Cc1ccc(-c2noc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)n2)cc1 +Oc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(-c3ccccc3)c2c1 +COc1ccc(Oc2c(Cl)cnn(-c3cccc(C(F)(F)F)c3)c2=O)cc1 +CN1CCCCC1CC(=O)N1c2ccccc2C(=O)Nc2cccnc21 +CN1C(=S)OC(C)(C)c2cc(-c3ccc(C#N)[nH]3)ccc21 +Cc1ccc(C2CC2COc2cc(NCc3cnn(C)c3)c(=O)n(C)n2)nc1 +CN(C(=O)c1ccc(OCC2CC2)cc1)C1Cc2ccc(CNCC3CCOCC3)cc2C1 +C#CC(CC)(CC)Nc1nc(NC)nc(-n2cncn2)n1 +CCOC(=O)CC(=O)Nc1scnc1C(=O)Nc1nccs1 +COc1ccc2cc(C(O)C(C)N3CCN(Cc4ccccc4)CC3)ccc2c1Cl +O=C1C2Cc3ccccc3CN2C(=O)N1CCCN1CCN(Cc2ccccc2)CC1 +O=S(=O)(c1cccc(Cl)c1)n1cc(Cl)c2cc3c(cc21)CCNCC3 +COC(CNc1cc(Oc2c(C)cc(C#N)cc2C)cc(Nc2ccc(C#N)cc2)n1)OC +NCCS(=O)(=O)NC(=O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1 +COc1ccc(N2Cc3c(nc(C)c(CN)c3-c3ccc(Cl)cc3Cl)C2=O)cc1 +O=C(Nc1ccc(-c2noc(CNCC3CCCO3)n2)cc1)N1Cc2ccccc2C1 +CC(C)(C)c1ccccc1S(=O)(=O)c1ccc(C(C)(O)C(F)(F)F)cc1 +NS(=O)(=O)Oc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1 +N#Cc1cccc(C2=Nc3cc(N4CCS(=O)(=O)CC4)c(C#Cc4ccccc4)cc3NC(=O)C2)c1 +Cc1ccc(C(=O)Nc2ccc(Cl)cc2)c(NC(=O)c2sc3ccccc3c2Cl)c1 +Cc1cccc2cc(C#N)c(SCC(=O)N3CC(=O)Nc4ccccc43)nc12 +Cc1ccc(-n2cc3c(n2)c(NC2CCCCC2)nc2ccccc23)cc1 +O=C(NC(CO)CO)c1ncncc1Nc1ccc(I)cc1F +CC(=O)OCC(Cc1ccccc1)NC(=O)C(Cc1ccc(O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21 +CCOC(=O)N1C2CCC1CC(c1c(C)cnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn13)C2 +COC1COCCC1NC1CC2CN(C(C)=O)CC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +Cc1ccccc1-c1nccnc1C1CN(c2ncc3ccccc3n2)C1 +C=CCC12CCC(O)CC1=CCC1C2CCC2(C)C(O)CCC12 +NC(=O)n1cc(CC(=O)N2C(C(=O)Nc3cccc(OC(F)(F)F)c3)CC3CC32)c2cc(OCCO)ccc21 +Cc1cccc(Cl)c1NC(=O)c1ccc(-c2cc(Cl)ccc2Cl)o1 +NC(=O)c1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +CCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(F)c4)c3)nc2n(C)c1=O +CCCCCCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1F +O=C(O)Cc1ccc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)cn1 +NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O +Clc1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1Cl +CCOc1ccc2c(c1)cc(CN(C(C)=O)C1CCCC1)c1nnnn12 +CCc1ccc(C2OC(COC(=O)OCC3CC4CCC3C4)C(O)C(O)C2O)cc1Cc1ccc2c(c1)OCCO2 +O=C(Cc1ccc(-c2ccccc2)cc1)Nc1nc2nn(CCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +O=C(O)C1CCN(Cc2cc3nc(O)c(O)nc3cc2Br)CC1 +CCC1(c2ccc(CSc3ccc(Br)cc3)cc2)Oc2ccccc2-n2cccc2C1=O +CSc1ccc(CNC(=O)c2ccc(C(C)(C)C)cc2)cc1 +Cc1cc2c(cc1Cc1ccc(C(=O)NCc3cccc(CNc4nccc(C(F)(F)F)n4)c3)o1)C(C)(C)CCC2(C)C +COc1ccc(C(=O)C=Cc2ccc(CN3CCCCC3)c(O)c2)cc1 +COc1ccccc1-c1ccc(OC2OC(CO)C(O)C(O)C2O)c(Cl)c1 +Nc1ncc(CNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)s1 +N#Cc1cccc(-c2ccc(C(=C3CCN(CC4CC4)CC3)c3nc4cc(F)c(F)cc4[nH]3)cc2)c1 +O=C(Nc1cccc(OCc2ccc(-c3cc(F)c(F)c(F)c3)cc2)c1)C1CCNCC1 +O=C(Nc1ccc(C2CCN(C(=O)C3CC3)CC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F +c1ccc(-c2ccc(Cc3cncc4ccccc34)cn2)cc1 +CC1(C)CCC(C)(C)c2nc(C(=O)Nc3ccc(C(=O)O)cc3)cnc21 +CCCCCCOP(=O)(O)C1=CC(OC(CC)CC)C(NC(C)=O)C(NC(=N)N)C1 +Cc1ccc(C(=O)Nc2cccc(N(C)C)c2)cc1Nc1ncnc2cnc(N3CCCCC3)nc12 +N#Cc1cnc2cnc(NCCN3CCOCC3)cc2c1Nc1ccc(Sc2ccccc2)cc1 +CCCn1c(=O)c2nc(-c3cnn(Cc4noc(-c5ccccc5Cl)n4)c3)[nH]c2n(CCC)c1=O +Cn1c(=O)c2c(CC(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)coc2n(C)c1=O +O=C(c1nn(C2CCCN(CC3CCOC3)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CN(C(=O)c1ccc(-c2ccc(F)cc2)cc1)C1CCc2cc(CN3CCS(=O)(=O)CC3)ccc2C1 +CNC(=O)Cn1cc2nccc(Nc3cc(-c4cc(C)ccc4F)ncc3C)c2n1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3cccc(C(=O)NC4CCOCC4)c3)nc2n1 +COc1cc(OC)nc(Sc2cccc(C(C)=O)c2C(=O)O)n1 +NS(=O)(=O)OCC1CC(Cc2cc(NC3CCc4ccccc43)ncn2)CC1O +Cc1cn(-c2ccc3n(c2=O)CCN(CCOc2ccc(F)c4nc(C(F)(F)F)sc24)C3=O)cn1 +Cn1cnc(S(=O)(=O)N(Cc2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)Cc2c(F)cccc2Cl)c1 +CS(=O)(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2C2CCN(c3ccccn3)CC2)C1 +CCC(C)OC(=O)C(C)NP(=O)(OCC1OC(C#N)(c2ccc3c(N)ncnn23)C(C)(O)C1O)Oc1ccccc1 +COc1ccc(C(=O)c2ccc3c(-c4ccc(OCC(=O)O)cc4)nocc2-3)cc1 +O=C(CCOc1ccc(CN2CCCCC2)cc1)N1CCC(Cc2c[nH]cn2)CC1 +O=C(Nc1ccc(-c2nnc(NCCCCN3CCCOCC3)o2)cc1)c1ccccc1F +OCC1OC(n2ccc3c(-c4cc5ccccc5o4)ncnc32)C(O)C1O +O=C(OCCc1ccccc1)c1cc(NCc2cc(O)ccc2O)ccc1O +COc1cccc2cc(C(=O)Nc3c(C#N)ncn3-c3ccc(F)cc3)c(=N)oc12 +CC(c1ccccc1)N1C(=O)C(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)SC1c1ccccc1 +CCCCCCCCCCC(O)C1CCC(C2CCC(C(O)CCCCCCCCCCC(O)CC3=CC(=O)OC3C)O2)O1 +O=c1nc[nH]c2cc(-c3cnc4nc(N5CCC(N6CCCCC6)CC5)oc4c3)ccc12 +CCOC(=O)c1cc(-c2sc(-c3cccnc3)nc2-c2ccccc2)n[nH]1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1cc(F)c(Cl)cc1-c1cn[nH]c1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1cccc(F)c1F +CC1(C(=O)NC(Cc2cccc(F)c2)C(=O)O)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)n1 +CC1C(=O)N(Cc2ccccc2)c2ccccc2C(C)N1C(=O)NCc1ccccc1 +NC1CCC(Nc2ncc(Cl)c(-c3cccc(NCc4cccc(F)c4)n3)n2)CC1 +[C-]#[N+]C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1[S+](C)[O-] +CCCCc1nc(Cl)c(CO)n1Cc1cccc(C(=O)c2ccccc2C(=O)O)c1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2ccc(F)c(F)c2)CC1 +CCOC(=O)c1nc(-c2ccc(NC(=O)Nc3ccc(NC(C)=O)cc3)cc2)nc(N2CCOCC2)c1OCC +CC1(C(=O)NC(Cc2ccc(C(F)(F)F)cc2)C(=O)O)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CC#CC(CC(=O)O)c1ccc(OCc2ccccc2-c2ccccc2)cc1 +N#Cc1cc(F)ccc1-c1noc(CCC(=O)Nc2ccc3c(c2)c2ccccc2n3CCF)n1 +CCN(CC)CCOc1ccc2c(c1)C(C)(C)c1oc3cc(F)ccc3c1C2=O +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2Cc3[nH]ncc3C1CC(c1ccc(-c3cncs3)cc1)C2 +CN1CCCC1Cc1c[nH]c2ccc(C3=CCN(C(=O)Nc4cccc5ccccc45)CC3)cc12 +O=C(C=Cc1cccn(CCCc2ccc(Cl)cc2)c1=O)NO +COc1cccc(CN2CCC(NC(=O)c3cc(=O)c4ccc(F)cc4o3)CC2)c1 +COc1ccc(-c2nc(COc3cc(OC)cc4oc(-c5cn6nc(C)ccc6n5)cc34)cs2)cc1 +Cn1cc(-c2ccc3ncc4ccc(=O)n(-c5ccc(F)c(Cl)c5)c4c3c2)cn1 +COCc1ccc(Cn2ccc3nc(-c4ccccc4F)nc-3c2)cc1 +C=CC(=O)Nc1c(F)cccc1Nc1cc(N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)ncn1 +COc1ccc2c(Cc3c(Cl)cncc3Cl)n[n+]([O-])cc2c1OC1CCCC1 +COCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5cccc(F)c5)co4)cc3)cc2)C(=O)NC(=O)NC1=O +O=C(C=Cc1cnccc1-c1cn[nH]c1)Nc1ccc(CN2CCOCC2)cc1 +NCCCC1NC(CNC(=O)C=Cc2ccc(Br)cc2)CCN(CC(c2ccccc2)c2ccccc2)C1=O +Cc1cc2c(cc1Cc1ccc(C(=O)NCC3CCC(CNc4nccc(Cl)n4)CC3)o1)C(C)(C)CCC2(C)C +CC(C)(C)c1nc(-n2ccc(=O)[nH]c2=O)c2ccc(-c3ccc(NS(C)(=O)=O)cc3)cc2n1 +CC(CCN1CCOCC1)CC(=O)Nc1ccc(C(=O)Nc2nccs2)cc1 +O=C(NCCn1cccn1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CNC(=O)C12CC1C(n1cnc3cnc(C#Cc4ccc(F)c(F)c4)nc31)C(O)C2O +CCCCc1cn(-c2ccccc2C(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1 +COC(c1ccc(Cl)cc1)(c1ccc2cnccc2c1)c1cncn1C +O=C(O)CC(c1cccc(-c2ccc3c(c2)OCCO3)c1)c1nccs1 +Brc1cc2c(NC3=NCC4(CN5CCC4CC5)O3)ncnn2c1 +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1-c1cc(-c2ccccc2)on1 +O=C(CC1CCCCN1c1cc(-n2ccnc2)ncn1)NCc1ccc2c(c1)OCO2 +CC(C)c1ccc2[nH]c(O)c(N=NC(=O)c3cccc(S(=O)(=O)N4CCCCC4)c3)c2c1 +COc1ccc(OCc2cccc(C(=O)O)c2)cc1Cc1cnc(N)nc1N +Cc1nn(Cc2ccc(-c3nc4ccc(C(F)(F)F)cc4[nH]3)cc2)c(C)c1CC(=O)O +COc1c(O)ccc2c1cnc1c3cc4c(cc3ccc21)OCO4 +CNC(C)C(=O)NC1COc2c(C(=O)N3CCN(CCO)CC3)cccc2N(Cc2ccc(Br)c3ccccc23)C1=O +O=C(NCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +N#CN=C(NCC12CC3CC(CC(C3)C1)C2)Nc1cccc2ncccc12 +COc1cc2c(N)nccc2cc1CC(C(=O)O)N1CCC(NS(=O)(=O)c2cnc(N(C)C)c(C)c2)C1=O +CC(C)(C)NC(=O)NC(Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1 +O=C(CC1(c2ccc(C(F)(F)F)cc2)C2CC3CC1CC(C2)C3O)N1CC(O)C1 +Cc1cc(C2=NNC(=O)CC2C)ccc1N=C1CCCC(O)=C1Cc1ccccc1 +CN(C)Cc1ccc(-n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)cc1 +COc1cc2ncnc(Oc3ccc(NC(=O)NC(=O)c4ccccc4C)cc3)c2cc1OC +CCC(O)C#Cc1csc2c(NCC(N)Cc3ccccc3)nc(-c3ccncc3)nc12 +CC(Oc1ccccc1)C(=O)N1CCN(C(=O)c2cc(COc3ccccc3C(N)=O)ccc2F)CC1 +COc1cccc(Nc2cc(-c3cccc(-c4cccc(C(=O)NC5CC5)c4)c3)nc3c2C(=O)NCC3)c1 +Oc1ccc2c(c1)C13CCN(Cc4ccccc4)C(C2)C1(O)Cc1cc2ccccc2nc1C3 +CCn1c(=O)c2c(nc(COc3ccccc3)n2C)n(CC)c1=O +O=C(C1CCCN(c2ccc3nc(-c4cncc(C5CC5)c4)[nH]c3n2)C1)N1CCCC1 +Cc1ccc2ccc(C(Nc3cccnc3)c3ccccc3F)c(O)c2n1 +COc1cc(Oc2ncnc3ccn(C)c23)ccc1NC(=O)Nc1cccc(C(F)(F)F)c1 +O=C(Nc1cccnc1)C1CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +Oc1ccc(C2CC2CN2CCN(c3ccc(Cl)cc3Cl)CC2)cc1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1ccc(-c2ncc(C3(C(F)(F)F)CC3)[nH]2)c(F)c1 +CC(C)C(NC(=O)C(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCc1ccccn1 +Oc1ccc(OCC(O)CNC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)cc1 +Nc1ncc(-c2cnn(CCCN3CCC(O)C3)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 +Cc1ccccc1CCNCc1cccc(COc2nn3c(C(F)(F)F)nnc3c3ccccc23)n1 +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)cc1-c1ccc(Cl)cc1 +CNC(=O)c1cc(C)nc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 +O=c1c(OCc2ccc(Cl)cc2)c(-c2ccccc2)oc2cc(O)cc(O)c12 +COc1ccccc1OCCN1CCN(c2cnn(CCCN3CCN(c4ccccc4OC(C)C)CC3)c(=O)c2Cl)CC1 +CCNCC#CCCC(=O)C(O)(c1ccccc1)c1ccccc1 +C#Cc1cccc(Nc2nc3c(-c4nnc[nH]4)cccc3c3cnccc23)c1 +CNC(=O)CNC(=O)Nc1nc2ccc(-c3cncc(S(=O)(=O)NC(C)(C)C)c3)cn2n1 +O=C(c1ccc(F)cc1)N1CCN(Cc2ccc(-c3ccc(F)cc3)[nH]2)CC1 +CC1(C)Oc2ccc(-c3cc(F)cc(Cl)c3)cc2C2(COC(N)=N2)C12COC2 +Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCCC1CCN(CCC(C)C)CC1 +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(Cl)c(Cl)c2)CC1 +COc1cc(C=Cc2nc3n(n2)CCCC3c2cc(F)c(F)c(F)c2)ccc1-n1cnc(C)c1 +CCCn1nc([N+](=O)[O-])c(C(C#N)c2nc3ccccc3s2)c(Cl)c1=O +Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)CCCO2 +O=c1[nH]c2ccccc2n1C1CCN(Cc2csc3ccccc23)CC1 +CN1C(=O)C=CC2(C)C3CCC4(C)C(C(N)=O)CCC4C3CCC12 +Cc1c[n+](CC(N)=O)ccc1C=Cc1cccc2ccccc12 +Oc1ccc2c(c1)C1(CCCc3ccccc3)CCN(CCc3ccc(F)cc3)CC1O2 +CCOC(=O)C1=CCCCC1S(=O)(=O)Cc1cccc(Cl)c1 +CCCS(=O)(=O)c1nc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)cc(OC)n1 +Cc1cc2c(c(=O)o1)C=C1CCC(C(C)CNCc3ccc(O)cc3)CC1O2 +O=C1C=C(NCCCNc2ccnc3cc(Cl)ccc23)C(=O)C=C1NCCCNc1ccnc2cc(Cl)ccc12 +CCCn1cc(C(=O)c2ccc(OCC)c3ccccc23)c2ccccc21 +CCN1CCc2cc(O)cc3c2C1Cc1ccc(O)c(O)c1-3 +O=c1cc(-c2ccc(CN3CCCCC3)cc2)oc2ccccc12 +O=C1CSC(=O)N1CCCCCCCCNCC1CCc2ccccc2O1 +CC1(O)CCC(Nc2nccc(-n3ccc4c(N5CCC(S(C)(=O)=O)CC5)cccc43)n2)CC1 +Cc1cnc(-c2cc(Cl)ccc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c(NCCO)n1 +CCn1c(C)c(C)c2cc(-n3ccccc3=O)nc(NCc3c(C)cccc3C)c21 +CC1C(=O)NC(Cc2ccc(F)cc2)C(=O)NCCCCCOCCNC(C2CC2)C(=O)N1C +CN1CCCN(C(=O)c2cc3c(F)cccc3[nH]2)CC1 +CC(C)(O)CNC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +N#Cc1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc1 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+CN(C)c1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccc(C3CC3)cc2n1 +Nc1nc(N)c(-c2ccc(NC(=O)Cc3ccsc3)cc2)c(COCc2ccccc2)n1 +O=C(O)Cc1cccc2c(NCc3cccc(-c4ccnc5c(C(F)(F)F)cccc45)c3)cccc12 +O=C(NC1C(=O)N(c2ccccc2)C1c1cccnc1)c1ccc(Cl)s1 +OCC1OC(n2cnc3c(NC4CC5CCC4C5)nc(Nc4ccccc4)nc32)C(O)C1O +COc1cc(-c2cc(OCC3(CC#N)CC3)c3cccnc3c2)cc(OC)c1OC +N#CC1(n2cc(C(NC(=O)c3ccccc3)C3CCCCC3)nn2)CC1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCN(Cc2ccccc2C(F)(F)F)C1 +COC1CCC(C(=O)N2CCC(N3CCN(C(=O)c4cc(-c5ccccc5)nc(-c5ccccc5)c4)CC3)CC2)CC1 +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(CC(N)=O)ccc3N2)c(O)c2ccccc21 +COc1ccc(C(NC(=O)c2ccc3cnccc3c2)C2CCNCC2)cc1F +NS(=O)(=O)OCC1OC(n2cnc3c(NCc4cccc5ccccc45)ncnc32)C(O)C1O +COc1cc2c(N)nccc2cc1CC(C(=O)O)N1CCC(NS(=O)(=O)c2cnc(N(C)C)s2)C1=O +CCCNc1cc(NC(=O)c2cccs2)cc(C(F)(F)F)c1 +CS(=O)(=O)c1ccc(-c2c[nH]c3ccc(-c4nnc(N)o4)cc23)nc1 +CC(C)N(C)C1CCN(c2nc(-c3ccc(C(=O)NC4(C(=O)NCC#N)CCCCC4)cc3)cs2)CC1 +COc1cccc(S(=O)(=O)N(C)c2ccc(Oc3ccccc3)cc2)c1 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+O=C1N(Cc2ncoc2-c2ccccc2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCC3Cc4ccccc4N3)cc12 +CC(C)NC(=O)c1cnn2ccc(N3CC(O)CC3c3cccc(F)c3)nc12 +CCN1CCN(CCS(=O)(=O)c2ccc(-c3cc4ncn(C)c(=O)c4c(NCCCO)n3)cc2)CC1 +Fc1ccc(CCCCN2C3CCCC2c2c([nH]c4ccccc24)C3)cc1 +Cc1cc(N2CC(C)NCC2C)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +CC1=C2CCc3cc(C=Cc4ccccc4)ccc3N2CCC1=O +CC1CCN(c2nc(C(C)(C)C)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +OCC(O)C1C2CCC(CC2)C1Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F +CCN(CC)CCCN(CC)CCCNc1ccnc2cc(Cl)ccc12 +COc1ccc(C2C(C(=O)O)C(c3ccc4c(c3)OCO4)CN2CC(=O)N(CC(C)C)CC(C)C)cc1 +CCn1ncc2c(-c3cncc(Br)c3)c(C#N)c(C)nc21 +O=C(Cc1ccccc1)N1CCNC2CCCC(N3CCCC3)C21 +O=C(Nc1ccccc1F)C1=C(O)CCn2c1nc1ncccc12 +COc1cc(C(C)C)c(Oc2cnc(NC(C)(C)CO)nc2N)cc1I +O=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC3)cc21 +O=C(c1cccc(C(F)(F)F)c1Cl)N1C2CCCC1c1nnc(-c3cccnc3)n1C2 +COc1cccc(N2CN(CCc3ccccc3)CN=C2S)c1 +COc1ccc(S(=O)(=O)N2CCN(Cc3nc4cccc5c(=O)[nH]nc([nH]3)c45)CC2)cc1 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+Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCN1CCCCC1 +CC(C)c1cn(-c2nc(C(=O)O)cs2)c2cc(Cl)ccc12 +O=C(Nc1cccc(Br)c1)c1ccc(N2CCCC2)c(C(F)(F)F)c1 +Cc1c(OCCCCCN2CCC(O)CC2)ccc2c(=O)cc(-c3ccccc3)oc12 +CCCCC(CC)OC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +O=C(O)COc1cccc2cc(CCNCC(O)c3cccc(Cl)c3)[nH]c12 +COc1cccc(-c2cccc(C3(C)CSCC(N)=N3)c2)c1 +O=C(C1CNCCC1(O)c1ccc(F)c(F)c1)N(Cc1cn(Cc2cccc(OC(F)F)c2)c2cccc(F)c12)C1CC1 +CC(C)(C)OC(=O)Nc1cc(CN2C(=O)N(c3ccc(SC(F)(F)F)cc3)C(=O)C2(C)C)ccn1 +CCC(=O)N(c1ccccc1)C1(C(=O)OCCF)CCN(CCc2ccccc2)CC1 +CCCc1c(OCCCOc2ccc(OCC(=O)O)cc2)ccc2c(-c3ccccc3)noc12 +Cc1nc(NCc2nnc(C)s2)cc(OCC2CC2c2ccc(C3CC3)cn2)n1 +CSC(N)=NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +N=C1NC23C(C4NC(=N)N2CC(OS(=O)(=O)O)(CC2C(CO)CON2C4=O)C3(O)O)N1COC(=O)NO +CCCN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(c3ccc(Br)cc3)=NN12 +CCC(CC)(CNC(=O)C1CCN(Cc2ccc(F)cc2)CC1)c1ccc(F)cc1 +CCCC(C)COc1ccc(C(CNC(=O)C(N)CC2CC2)NC(=O)C(C)c2ccccc2)cc1 +O=C(O)CCC(=O)NC(CC(=O)O)Cc1ccc(-c2cccc(F)c2)cc1 +COc1ccccc1C(=O)Nc1cc2c(cc1N(C)C)n(C)c(=O)n2C +CC(C)Oc1cc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)ccc1F +O=C(NC1CCc2cccc3c2N(C1=O)C(C(=O)O)C3)C(S)Cc1ccc(-c2ccccc2)cc1 +c1ccc2nc(N3CCC(Oc4nccnc4C4CCOCC4)C3)ccc2c1 +Cc1cn(CC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)nc1C +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2cccs2)cc1Cl +Cc1ncoc1-c1nnc(SCCCN2CCc3cc4nc(CC5CC5)oc4cc3CC2)n1C +NCc1ccccc1-n1nc(C(F)(F)F)cc1C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1 +CC1CN(c2sc(Br)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21 +CC(C)(C)OC(=O)N(C(=O)c1ccccc1)C1=NC(C)(c2nc(Br)ccc2F)CC(C(F)(F)F)O1 +CCc1ncnc(-c2cc(F)c(C(=O)N3CCN(C4COC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCC1OC(c2ccc(Cl)c(Cc3ncc(-c4ccoc4)cn3)c2)C(O)C(O)C1O +O=C(C=Cc1cccnc1)c1ccc(-c2ccccc2)cc1 +CC(C)(O)C1CCC(Nc2ccc3ncc(-c4cccc(F)c4)n3n2)CC1 +c1cc(OCCN2CCSCC2)cc(-c2nc(N3CCOCC3)c3oc4ncccc4c3n2)c1 +CNC(c1cccc(O)c1)C(C)(C)C(=O)NCCc1ccccc1 +O=C(C=Cc1ccc(O)c(O)c1)OC(C(=O)O)C(OC(=O)C=Cc1ccc(O)c(O)c1)C(=O)O +Cc1cc(C)c(C=C2C(=O)NN=C2c2snnc2C)[nH]1 +Fc1ccc(CNc2ncnc3c2cnn3CC(Cl)c2ccc(Cl)cc2)cc1 +COC(C)(C)C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +CC(c1cccc(NC(=O)c2ccc(N3CCCC3)cn2)c1)N1CCC(C(=O)NC2CCCCC2)CC1 +COc1ccc(C(NC(=O)c2ccc3cnc(NC4CC(O)C4)nc3c2)c2cnn(C)c2)cc1F +CN1C(Nc2nc3ccccc3s2)=NCC12CN1CCC2CC1 +NC(CC(=O)NC1(c2nnc(-c3ccccc3)o2)CCS(=O)(=O)CC1)Cc1cc(F)c(F)cc1F +O=C(Nc1ccc(Oc2cncc(C(=O)NCCN3CCOCC3)c2)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +COc1ccccc1Cc1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc1-2 +CCOc1cc(N2CCN(C)CC2)ccc1Nc1nc(N)n(C(=O)NCc2ccccc2S(=O)(=O)C(C)C)n1 +O=C(Nc1cccc2cnccc12)NC1CCc2cc(F)ccc2C1Cc1cccs1 +CCCCC(Sc1nc(OCCc2ccc(C(F)(F)F)cc2)cc(OCCc2ccc(C(F)(F)F)cc2)n1)C(=O)O +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc3c(c2)OCC3)cc1 +CN(c1ccnc(Nc2cccc(CO)c2)n1)c1cccc2[nH]ncc12 +FCCc1ccc(C2(c3cccs3)CC3c4ccccc4C2c2cccc[n+]23)s1 +CC(C)C(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)C(=O)Nc1nncs1 +Cc1cccc(CNc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +CN1Cc2cc(CN3CCOCC3)ccc2C(c2cc3ccccc3s2)C1 +CCCCCCN1NN=C(NC(=O)Nc2c(C(C)C)cccc2C(C)C)N1 +CC1=CC(C)(C)Nc2ccc3c([nH]c4ccccc43)c21 +COc1cc(Cl)ccc1-c1cc(OC)c(-n2c(=O)ccc3cc(S(=O)(=O)Nc4ccon4)ccc32)cc1F +CCOC(=O)C1=C(C)NC2=C(C(=O)C(C(=O)OC)C(C)C2)C1c1cc(Br)c(OC)c(OCC)c1 +Cc1ccc2c(c1)[n+]([O-])c(NCCN1C(C)CCCC1C)n[n+]2[O-] +CCC(C)C(NC(=O)c1cccc(CN)c1)C(=O)NC(CCc1ccccc1)C(=O)CO +COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N2CCCC2)c1=O +CNC(=O)C(NC(=O)C(CCc1ccccc1)CP(=O)(O)Cc1ccc(Cc2ccccc2C)cc1)C(C)(C)C +NC(=O)Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 +NCCCNCCCCNCCCNCc1ccc(OC2=CC(=O)c3ccccc3C2=O)cc1 +CCn1ncc2c(NC3CCOCC3)c(C(=O)N3CCCC3)cnc21 +Cc1cc(C(=O)Nc2ccccc2)c2ccc(-c3ccc(OCC(C)(C)C(=O)O)[n+]([O-])c3)cc2n1 +CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(-c2ccccn2)n1 +Cc1c(O)cccc1C(=O)NC(Cc1cc2ccccc2s1)C(O)CN1CC2CCCCC2CC1C(=O)NC(C)(C)C +CC(C)CC(NC(=O)C(Cc1cccc2ccccc12)NC(=O)N1CCOCC1)B(O)O +Cn1c(-c2ccco2)nc2c(NC(=O)Cc3ccccc3)ncnc21 +Cc1ccc2[nH]cc(C(=O)OCC34CCN(CC3)CC4)c2c1C +CCCCCCC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)COc3ccc(O)cc3)cc2)cc1 +CCC(NC)C(=O)NC(C(=O)N1CC2Cc3cc(Cl)ccc3N2CC1C(=O)NC1CCOc2ccccc21)C1CCCCC1 +Cc1nc(N2CCN(C(=O)C3CCCC3)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +c1ccc(COc2ccc3c(c2)CCN(C2CCCC2)CC3)cc1 +CCC1CS(=O)(=O)c2cc(C(=O)N=C(N)N)c(C)cc21 +CC12CCCOC1C1(COC(N)=N1)c1cc(-c3cccnc3F)ccc1O2 +CC(C)(C)OCC(=O)NC1CC2CN(c3ccc(OC(F)(F)F)cc3)C(=O)N2C1 +CCCC(CCC)C(=O)Nc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O +COc1cc2[nH]c(-c3ccccc3)c(C=O)c2cc1-c1cnco1 +Cc1[nH]nc2c1C(=NN=C(N)N)CC(c1ccccc1Cl)C2 +O=C1CN2Cc3cc(OCCCC(=O)N4CCCCC4)ccc3N=C2N1 +COc1ccc(NNC(=O)C(=O)c2c[nH]c3ccccc23)cc1 +O=C(O)c1ccc(C2=CC3(CCNCC3)Oc3ccccc32)cc1 +O=C(Nc1ncc(CCO)s1)N1CCC(c2noc3ccc(F)cc23)CC1 +CC(C)(C)c1ccc(C(=CC(=O)Nc2ccc3c(c2)OCCO3)c2ccc(Cl)cc2)cc1 +O=S1(=O)CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +CCC(CC)C(N)CCN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1 +NNC(=O)c1cn(-c2ccc(S(N)(=O)=O)cc2)nc1-c1ccc(Br)cc1 +CCCC(C)n1c(CC)nc2c(-c3ccc(O)nc3C(F)(F)F)ccnc21 +COc1ccc(C(=O)CSc2nc(CN3CCCc4ccccc43)c(C)c(=O)[nH]2)cc1 +O=C1CC2(CCN(C(=O)Nc3ccc(C(F)(F)F)cc3)CC2)Oc2c(Cl)cccc21 +Cc1cc(CN2CCN(CO)CC2)ccc1C(=O)Cn1ccc(OCc2ccccc2)cc1=O +O=C(Nc1cc(N2CC(F)(F)C2)cc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)cc1F +O=C1NC(=O)C2=C1c1cn(c3ccccc13)CCCOC(CO)CCn1cc2c2ccccc21 +CN1OC2(N=C1N)c1cc(C3CC3)ccc1CC21CCc2ccccc2CC1 +N#CC(Cc1ccc(-n2cc(COC(=O)N3CCCC3)nn2)cc1F)NC(=O)C1NC2CCC1C2 +[N-]=[N+]=NCc1ccc(C(=O)CC(=O)C(=O)O)cc1CN=[N+]=[N-] +Cc1c(Cc2ccc(C(=O)O)cc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCNC2=O +O=C(NCCS(=O)(=O)c1ccc(C(F)(F)F)cn1)c1ccc(Br)cc1F +CC(C)(C)C(=O)NCCCCCN1CCN(c2ccc(Cl)cc2)CC1 +Fc1ccc(C=Cc2ccc(-c3ccc(Br)s3)s2)cc1 +O=C(CCN1CC=C(c2ccc(F)cc2)CC1)c1ccccc1 +O=C(O)CCCCn1nnc(-c2ccc(C(=O)N3CCC(N4CCC(Oc5ccc(Cl)c(Cl)c5)CC4)CC3)cc2)n1 +O=C(NCCCCN1CCCN(C(c2ccccc2)c2ccccc2)CC1)c1cc2ccccc2s1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(c3ncccc3C(F)(F)F)CC2)cc1 +NCCNCCNC(=O)COc1ccc2sc(CNc3nncc(-c4c(Cl)cccc4Cl)n3)nc2c1 +CN(C)CC(=O)NC(COc1cncc(-c2ccc3cnccc3c2)c1)Cc1c[nH]c2ccccc12 +CC1CCC(=O)N1c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1 +O=C(Nc1cccnc1)C(=O)c1cc(Cc2ccccc2)n2ccccc12 +Cn1nnnc1-c1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1 +CC(C)Oc1ccc(Nc2ncc(CCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +O=c1c(-c2ccccc2F)cc(-c2ccccn2)cn1-c1ccccc1 +NS(=O)(=O)c1ccc(Nc2nc(F)nc(NCCO)n2)cc1 +CC1c2c(cc(F)c(-c3cccc4cc[nH]c34)c2F)NC(C)(C)C1OC(=O)Nc1ccc(N(C)C)cc1 +COC(=O)N1Cc2c(-c3ccc(F)cc3)ncn2-c2ccccc21 +OCC1OC(c2ccc(Cl)c(Cc3nnc(C(F)(F)F)s3)c2)C(O)C(O)C1O +Cc1ccc2c(c1)CCN2CC(=O)NC1CCC(CNS(=O)(=O)C(C)C)CC1 +COc1ccc(NC(=NC(=O)c2ccc(F)c(F)c2)NC2CCCCN(CC(=O)N3CCCC3)C2=O)cc1 +Oc1cccc(N2CCc3cc(O)ccc3C2c2ccc(N3CCN(CC4CC4)CC3)cc2)c1 +Cc1ccc2[nH]c(C(=NO)C3CCN(C)CC3)cc2c1 +NC(=O)C(c1cccc(F)c1)(c1cccc(F)c1)c1cccc(F)c1 +O=C(O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCCCC2)c1=O +CC(N)C(=O)N1Cc2[nH]c3ccccc3c2CC1C(=O)O +O=C(NCc1ccc(F)cc1)c1cnc(Nc2cccc(Br)c2)cc1C(F)(F)F +Cc1ccc(-c2cn(-c3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)nn2)cc1Nc1nccc(-c2cccnc2)n1 +CC(=O)Nc1ccc(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)c(C)c1 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+O=C(Nc1ccc(C(F)(F)F)cc1)NC1CCN(C(=O)CC(F)(F)F)CC1 +Cc1ccc2c(Nc3ccc(N4CCN(C)C(C)C4)cc3)c(C)c(C)nc2c1C +N#Cc1c[nH]c2ncnc(N3CCC(N)(CNC(=O)c4ccc(F)cc4F)C3)c12 +COc1cc(Nc2c(C#N)cnc3ccc(C=CCCN4CCOCC4)cc23)c(Cl)cc1Cl +Oc1nc2cccc(N3CCN(Cc4cc(-c5ccc(F)cc5)ccn4)CC3)c2o1 +Cc1cc(-n2ccnc2C)c2cccc(OCc3c(Cl)cncc3Cl)c2n1 +COc1cc2c(cc1OCCO)Nc1cc(-c3ccc([N+](=O)[O-])c(OC)c3)ccc1C(=O)N2 +CC(=O)c1ccc(NC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 +Cc1cccc(NC(=O)OCc2ccc(-c3n[nH]c4c3Cc3cc(CN5CCN(C)CC5)ccc3-4)s2)c1 +CCN(CCCCCCNC1=CC(=O)C(NCCCCCCN(CC)Cc2cccc(OC)c2)=CC1=O)Cc1cccc(OC)c1 +CC1CN(c2cc(NS(=O)(=O)c3ccc(-c4cccs4)cc3)ccc2C#N)CC(C)N1 +Cc1c(Cc2cccc(NS(N)(=O)=O)c2F)c(=O)oc2cc(OC(=O)N(C)C)c(F)cc12 +CC(C)CC(NC(=O)C1CCNCC1)C(=O)NC(CCc1ccccc1)C(=O)c1nc2cc(S(N)(=O)=O)ccc2o1 +O=C1c2cc(OCCN3CCCC3)ccc2-c2ccc(OCCN3CCCC3)cc21 +Cc1cc(Cl)ccc1NC(=O)Nc1ccc(NS(N)(=O)=O)cc1 +CC(NC(=O)c1c(CN2CCC(N)CC2)c(-c2ccccc2)nc2ccccc12)C1CCCCC1 +CCN1CCN(c2cn(S(=O)(=O)c3ccc(F)cc3)c3ccc(Cl)cc23)CC1 +O=C(Cc1ccccc1)NCCCNCCCCNCCCNC(=O)Cc1ccccc1 +Cc1ccc2[nH]c(C(=O)NN(CC(C)C)c3nc(C#N)ncc3Br)cc2c1 +O=C(Nc1ccccc1-c1nc2cccnc2s1)c1cc(N2CCOCC2)nc(-c2ccccc2)n1 +CCCN(CCCNc1ccnc2cc(Cl)ccc12)Cc1cccc(F)c1O +NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CCc1ccc(-c2ccc(-c3ccccc3)cc2)cc1 +CN1C(=O)C(NC(=O)C(Cc2cscn2)NC(=O)OC(C)(C)C)N=C(c2ccccc2)c2ccccc21 +N#CC(Cc1ccc(N2CCNCC2)cc1F)NC(=O)C1NC2CCC1C2 +CCn1c(=O)c(-c2cc(C(=O)NC3CC3)cc(F)c2C)cc2nnc(-c3c(F)cccc3F)n21 +O=C(c1cccnc1)c1cc(-c2ccoc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1 +Cc1ccc(C(=O)NCc2cccc(C(C)(C)C)c2)cc1Nc1ncnc2cnc(N3CCCC3)nc12 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2ccc(C3(O)CCNCC3)nc2)c1 +CC(C)(c1nc(-c2cc(C(F)(F)F)cc3[nH]ccc23)nc2c1OCC1COCCN21)S(C)(=O)=O +CCOc1ccc(C2(CC(C)CCNCCCC(N)=O)CCC2)cc1 +Nc1ccc(Cn2cnc3c(Nc4cccc(N)c4)ncnc32)cc1 +CCOc1ccc2[nH]c(SCC(=O)Nc3ccccc3C(=O)OC)nc2c1 +CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCSCC3)cc2)c(O)cc1O +O=C(CCCCCCC(=O)Nc1ccc(-c2ccccc2)cc1)NO +CN(C)CCC(CNC(=O)Nc1cc(F)cc(F)c1)c1ccc(-c2cccc(C#N)c2)cc1 +c1cc(OCc2ccc3ccccc3n2)cc(OCc2ccccc2-c2nn[nH]n2)c1 +Cc1c(N(Cc2cc(F)c(F)c(F)c2)S(=O)(=O)c2ccc(C(=O)O)cc2)sc2ccccc12 +CN1CCCCC1COC(=O)C(C)(c1ccccc1)c1ccccc1 +NS(=O)(=O)c1ccc2c(c1)sc1nc(-c3cc4cc(Cl)ccc4oc3=O)cn12 +COc1ccc(S(=O)(=O)N(Cc2ccccc2)Cc2ccc(C(=O)NCc3ccccc3)cc2)cc1 +O=C(c1cc(Cl)cc(Cl)c1)c1cc(Cl)ccc1OCCn1ccc(=O)[nH]c1=O +O=C(CCl)Nc1ccc(SCC(=O)Nc2ccc(Cl)cn2)cc1 +COc1ccc(C(Oc2ccc(Cn3c(N)nc4cc(-c5cnn(C)c5)cnc43)cc2OC)C2CC2)cn1 +CC(C)(CC(=O)Nc1ccc(F)c(F)c1)NCC(=O)N1CCCC1C#N +O=C(O)CCNc1sc2c(c1Cc1nnc(SCC(=O)NNC(=O)c3ccccc3)n1NC(=O)c1ccccc1)CCCC2 +Fc1ccc(-c2[nH]c(C=Cc3ccccc3)nc2-c2ccncc2)cc1 +COc1cccc(Oc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ccccn2)c1 +Cc1cccc(Nc2nccc(-c3c[nH]c4ncccc34)n2)c1 +CC(C)(C[N+](C)(C)C)C1OC2CCCCC2C2C=CCCC21 +CCC(NC(C)=O)c1cc(Cl)ccc1C1CCN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2Cl)CC1 +COC(=O)C(C#N)=C(Nc1cccc2cc[nH]c12)NC1CCCCN(CC(=O)N2CCCC2)C1=O +CC(=O)N1CCCC1(Cc1ccc(F)cc1)C(=O)OCc1ccccc1 +CC1NC(=O)C2CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4C#N)cn3)C12 +CCN(CCN)C(=O)c1cc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)ccc1C +NC1CC1c1ccc(NC(=O)c2ccc(N3CCOCC3)cc2)cc1 +Cc1ccc2c(c1)CN(S(=O)(=O)c1cccc(C(=O)O)c1)CC2 +CNC(=O)c1ccc(N2C(=S)N(c3cnc(C#N)c(C(F)(F)F)c3)C(=O)C23CCC3)cc1F +c1ccc(C(CCNC2=NCc3ccccc3CN2)c2ccccc2)cc1 +O=C(Nc1ccc(S(=O)(=O)C(F)(F)F)cc1)c1cnc(N2CCC(O)C2)c(-c2cncnc2)c1 +CC(NC(=O)c1cnc(-c2ccccn2)nc1)c1cccc(-c2noc(C(C)(C)O)n2)c1 +NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3cccc(Oc4ccccc4)c32)cc1 +CN(C)CCn1c2c3c(n[nH]c(=O)c4cc(F)cc1c34)CC(C)(C)C2 +N#CSCC1CC(O)(c2ccccc2)CC(c2ccc(Br)cc2)O1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(Cl)cc1-c1ccnc(NC2CCC2)c1 +CN(C)c1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1F)=NC2 +CC1=C(C(=O)N2CCN(c3ccccc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc3c(n2)NC(=O)CO3)c1F +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc(F)c4onc(N)c34)cc2)c1 +CN(CC(C)(C)N1CCc2c(-c3cnc(N)nc3)nc(N3CCOCC3)nc21)S(C)(=O)=O +CCCCCCN1CC2C(C1)C2(CCC)c1cccc(NS(C)(=O)=O)c1 +CN(C)C12CC(OC(=O)C=Cc3ccccc3)C(C(c3ccccc3)C1)C(c1ccccc1)C2 +CNCC(O)C(c1cccc(F)c1)n1ccc2ccccc21 +N#CC1CCCN1C(=O)C1CC(NS(=O)(=O)c2ccccc2)CN1 +CC1CCCN1C1CCN(c2ccc(NC(=O)N3CCN(c4ccccc4)CC3)cc2)C1 +c1ccc2c(c1)c1cnccc1n2CCCCCCCn1c2ccccc2c2cnccc21 +CN(C)C(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 +COc1cc(C(=O)c2ccccc2)ccc1-c1nc(C2CCC2)n2ccnc(N)c12 +O=S(=O)(Nc1ccc(CCNCC(O)COc2cccnc2)cc1)c1ccc(Cl)c(Cl)c1 +CC(=O)N1CC=C(c2nccnc2OC2CN(C(=O)c3cc(C)c[nH]3)C2)CC1 +CC(C)n1ccc2cc3c(cc21)CCN3C(=O)Nc1cccnc1 +Cc1ccc(-c2ncc(C(=O)NC(C(N)=O)c3ccccc3)nc2-c2ccc(C)cc2)cc1 +O=c1ccc2cnc3ccc(-c4ccsc4)cc3c2n1-c1ccc(N2CCNCC2)c(C(F)(F)F)c1 +Cn1nc(-c2cc(NS(C)(=O)=O)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +O=C(Nc1ccccc1)N1CCN(Cc2cnc3ccccc3c2)CC1 +c1ccc(-c2cc3ccncc3cc2OC2CCNCC2)cc1 +CNC(=O)N(C)CC#Cc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +CCCCN(C)S(=O)(=O)CC1CC(N(C)c2ncnc3[nH]ccc23)C1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1S(=O)(=O)CCO +Nc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +Cn1cc(C2=C(c3cccs3)C(=O)NC2=O)c2ccccc21 +O=C(Nc1cc(Nc2cnccn2)nc(-c2ccnc(N3CCNCC3)c2)c1)c1cccnc1 +O=C1Nc2ccc(NC(=O)C(=O)N3CCC(Cc4ccccc4)CC3)cc2CO1 +COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(NC(C)C)n2)cc1 +CCN1CN(C2CCC(CNCC(F)F)CC2)c2c(cnc3[nH]ccc23)C1=O +COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3ccccc3NC(=O)c3cnc4ccccc4c3)cc1)CC2 +O=C(O)c1ccc(-c2n[nH]c3c2Cc2cc(CNC4CCC(O)CC4)ccc2-3)cc1 +CCC(C)C(NC(=S)Nc1ccc(C(F)(F)F)cc1)C(=O)NC(Cc1ccccc1)C(=O)Nc1cccc(Br)c1 +Cc1ccc(NC(=O)c2cccc(C3(C#N)CC3)c2Cl)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)n1 +CCOC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1-c1ccsc1 +CCCCc1c(C(=O)NCc2cncn2CC(=O)O)cnn1-c1ncc(C)c(-c2cccs2)n1 +COc1cccc(-c2cn(Cc3c(F)cccc3F)c(=O)n(CC(N)c3ccccc3)c2=O)c1F +CCC(CC)N1CCn2nc(-c3ccc(Cl)cc3Cl)c3nc(C)cc1c32 +Cc1c(Cc2ccccc2)nnc(N2CCC(O)(c3ccc(C(C)(C)O)cn3)CC2)c1C +COC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1-c1ccccc1C(=O)NC(Cc1ccccc1)C(=O)OC +Cc1cc(Cl)ccc1C1c2c(nn(CCCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F +NS(=O)(=O)c1nnc(NC(=O)CNC(=O)OCc2ccccc2)s1 +CC(C)c1nnc2ccc(-c3ocnc3-c3ccc(Cl)cc3Cl)cn12 +COc1ccc(-c2sc(N)nc2-c2cc(OC)c(OC)c(OC)c2)cc1N +COc1cc(F)ccc1-c1nc(Nc2cc(CS(C)(=O)=NC#N)cc(C(F)(F)F)c2)ncc1F +O=C(c1ccc(O)c(O)c1)c1nccc2cc(O)c(O)cc12 +CC1=CSC(OCC(F)(F)F)(c2ccccc2)c2noc(=O)n21 +Cn1c(=O)c(S(=O)(=O)c2ccc(F)cc2F)cc2cnc(Nc3cccc4[nH]ccc34)nc21 +O=C(NCC1(c2ccc(Cl)cc2)CCOCC1)c1cccc(Cl)c1Cl +CC1CCC(Cn2c(C(C)(F)c3ccccc3F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CC(=O)N1CC2CN(c3nc4ccccc4n(C4CCN(C5CCCCCCC5)CC4)c3=O)CC2C1 +CCCC(NC(=O)c1ccc(OC)c(Cl)c1)C(=O)OC +Cc1nc(-c2ccc(N(Cc3ccccc3)C(=O)c3ccc(O)cc3O)cc2C)c2ccccc2n1 +COc1ccc(CC(NC(=O)C(NC(=O)C(Cc2ccc(OC)cc2)NC(=O)c2ccc(F)cn2)C(C)C)B(O)O)cc1 +CCC(C)(C)C(=O)Nc1cc(CN2CCOCC2)c(C#N)cn1 +CCCCCCC(Sc1nc(Cl)cc(Nc2nc(-c3ccc(OC)cc3)cs2)n1)C(=O)O +N#Cc1ccnc(Nc2cc(C3CCN(C4COC4)CC3)cc(N3CCC(F)(F)C3)n2)c1 +COc1ccc(C=CC(=O)OC2C(O)c3c(cc(OC)c4c(=O)c5cc6ccccc6cc5n(C)c34)OC2(C)C)cc1 +Cc1cc(Sc2c([N+](=O)[O-])cc([N+](=O)[O-])cc2C(F)(F)F)c(Cl)cc1Cl +COc1cc(C=CC(=O)CC(=O)C=Cc2ccco2)ccc1O +CC(=O)Nc1cccc(C2CCN(CCCCCn3c(-c4ccccc4)nc4ccccc43)CC2)c1 +COc1ccc(-c2cnc3nc(N)nc(N4CCN(c5ccc(F)cc5)CC4)c3n2)cc1OC +COc1ccc2c(c1)nc(CCc1nc(-c3ccccc3)cn1C)n1nc(C)cc21 +CCOC(=O)Nc1cc2c(nc(SCc3ccc4c(c3)OCO4)n2N)c(N)n1 +CC(C)(O)c1cc(Nc2cc(C#N)ccn2)nc(N2CCC(F)(F)C2)c1 +CCCn1c(=O)c2nc(-c3cc(OCC(=O)N4CCN(c5ccc(F)cc5)CC4)nn3C)[nH]c2n(CCC)c1=O +CCCc1ccc(C2=CCN(CCOc3ccc(CC(OCC)C(=O)O)cc3)CC2)cc1 +CC12CC3CC(C)(C1)CC(C(=O)NNc1c(Cl)cncc1Cl)(C3)C2 +O=C(C1CCN(Cc2ccncc2)CC1)N1CCC(n2c(=O)n(Cc3ccc(Cl)cc3)c3ccccc32)CC1 +NCCC(=O)Nc1cccc2c1cnn2S(=O)(=O)c1cccc2ccccc12 +COc1ccc(C2=NN(C3CCN(C(=O)CN4C(=O)CCC4=O)CC3)C(=O)C2(C)C)cc1OCC1CC1 +Cc1cc(C(F)(F)F)c(-c2ccc(CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)c(=O)n1Cc1ccccc1 +Cc1cc(OCc2nc(-c3ccc(N4CCCCC4)cc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O +Cc1cc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)c(C(=O)NCc4cccnc4)n2CCO3)no1 +CCC1Nc2ncnc(N3CCN(c4ccccn4)CC3)c2N(Cc2ccc(Cl)cc2)C1=O +CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccc(F)cc1 +CN(C)C1Cn2c(-c3ccnc(Oc4ccccc4)n3)c(-c3ccc(F)cc3)c(=O)n2C1 +C=CCN(CC(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 +CC(C)Oc1ncccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(F)c12 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+Cn1c(-c2ccoc2)c(C2CCCC2)c2ccc(C(=O)O)cc21 +CS(=O)(=O)c1ccc(-n2nc(C(F)F)cc2-c2ccc(Cl)cc2)nc1 +Cn1c(=O)c(-c2ccccc2Br)cc2cnc(NCc3cccc(N)c3)nc21 +COC(=O)c1sccc1NC(=O)Cc1ccc2ccccc2c1 +O=C(Nc1ccc(F)c(F)c1F)NC1C2CC3CC(C2)CC1C3 +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c2cc(C2=CCCCO2)nc1F +CC(C)(NC(=O)c1ccc2c(c1)CCC1C2CCC2(C)C(c3cncc(F)c3)=CCC12)C(=O)O +O=C(Nc1c(F)cccc1F)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O +COCCCc1cc(CN(C(=O)C2CNCCC2c2cc(=O)n(C)c3cc(Cl)ccc23)C2CC2)cc(OCCOC)c1 +CC(NCc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 +COc1ccc(CCNC(=O)C(=O)C(Cc2ccccc2)NC(=O)CCC(=O)c2cc(OC)ccc2OC)cc1 +COC(=O)C(F)(C1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccn1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3)cc2n(CCC)c1=O +CCc1ccccc1Nc1ncc(C)c(-c2c[nH]c(C(=O)NC(CO)c3cccc(Cl)c3)c2)n1 +N#Cc1ccccc1COc1nn2c(-c3ccccc3)nnc2c2c1C1CCC2CC1 +Oc1ccc2cccc(Nc3ncc(-c4ccc(C(F)(F)F)cc4)o3)c2c1 +O=C1NCCN1c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1 +Cc1cc2ccccc2n1CCNC(=O)C=Cc1ccc(OCCCO)cc1 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+CN1CC(c2cc(OCc3ccc(F)cc3)ncn2)=C(O)C1=O +COc1ccc2nc(Nc3nc(O)c4ccc(N(C)C)cc4n3)nc(C)c2c1 +Cc1[nH]c(C)c(-c2ccc(Oc3ccccc3)cc2)c(=O)c1Br +COc1ccc(-c2cccc3cnc(Nc4ccc(-n5cnc(N6CCOCC6)n5)cc4)nc23)cc1F +CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3nc(-c4cc5ccccc5o4)cs3)cc2)CC(C)O1 +CN1CCCC1COc1cnc(Cl)c(-c2ccnc(F)c2)c1 +CN1CCN(C2CCN(C(=O)n3sc4c(ccc[n+]4[O-])c3=O)CC2)CC1 +O=C(C=Cc1ccc(O)cc1)CC(=O)C=Cc1cc(C(F)(F)F)ccc1F +Cn1nnnc1-c1cc(Br)cc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3)C2)c1 +Cc1cc2[nH]c(=O)c3cnn(C4CCOC4)c3c2cc1C(=O)N1CCC(OCC(F)(F)F)CC1 +COc1ccc(C2CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC2)c(C)c1 +COCCNC(=NC#N)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +O=C(CCCc1c[nH]nn1)NC1CCN(C(=O)OCc2cc(F)cc(Cl)c2)CC1 +CCC(C)CNCCc1c2c(nc3cc4c(cc13)OCCO4)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC +O=C1OCc2cc(CCC3C4CN(C(=O)Cc5ccc(-n6cnnn6)cc5)CC34)ccc21 +CN(C)Cc1nc(-c2ccc3[nH]nc(-c4cccc(C(=O)NCc5ccc(F)cc5)c4)c3c2)n[nH]1 +CC(CCOc1ccc(-c2ccc(Cl)cc2)cc1)CCN1CCN(c2ccncc2)C1=O +CCN(CC)CCOc1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1C(C)=O +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc4[nH]ccc4c3)nc2n1 +O=C(O)CCCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 +CC(Nc1ncnc(N)c1C#Cc1cnc(N)nc1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +CNC(=O)C1[Se]C(n2cnc3c(NCc4cccc(F)c4)nc(Cl)nc32)C(O)C1O +COC(=O)C1CCCN1C(=O)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C +COc1c(C)c2c(c(O)c1CC=C(C)CCC(=O)NC(C)C(=O)O)C(=O)OC2 +COc1cc(C(=O)N2CC(OC)C2)ccc1Nc1cc2c(-c3cnn(C4CCN(C)CC4)c3)cccc2cn1 +O=C(Nc1ccc(Cl)c(C(=O)Nc2cccnc2)c1)c1cccc(F)c1 +Cn1ncc2c1Nc1ccccc1N(C(=O)CCCCCCCN1CCN(Cc3cc(O)cc(O)c3)CC1)C2 +O=C(O)C1(c2ccc3c(c2)CCC(C(c2ccccc2)C2CCCCC2)C3O)CCCC1 +N#Cc1ccc(-c2nc(N)c3cc(Cc4ccccc4)sc3n2)o1 +N#Cc1ccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 +CCc1cc(C(C#CC2CC2)(OC)C(F)(F)F)c(O)nc1C +CC(C)c1ccccc1-c1cc2cccc(NC(=O)Nc3ccc(C(C)(C)C)cc3)c2o1 +CN1CCC(N2CCC(Oc3nc(-c4ccncn4)cc(=O)n3C)CC2)CC1 +Fc1ccc(-c2nc(-c3ccccc3)[nH]c2-c2ncnc3[nH]cnc23)cc1 +CN1CCC(=C2c3cc(Cl)ccc3C=Cn3cccc32)CC1 +COc1ccc2c(c1)c(C(=O)C1C(C)(C)C1(C)C)cn2CC1CCOCC1 +CC(C)c1cccc(C(C)C)c1NC(=O)CC(=O)CCCCCCCCCCOC1CCCCO1 +CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)cnc2OCC2(O)CCCC2)cc1 +CCCN(CCC)[P+](CC)(N(CCC)CCC)N(CCC)CCC +CCCC1=C(C(=O)OCC)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OCC)=C(C)N1 +CCNc1cc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)CCCC(C)C)cc(N2CCCC2=O)c1 +Cn1ccc2ncnc(Oc3cccc(NC(=O)c4ccccc4)c3)c21 +Cn1cc(-c2ccncc2)c(-c2ccc(OCc3nc4ccccc4n3C)cc2)n1 +CCc1ncnc(-c2cc(F)c(C(=O)N3CCN(CCCS(C)(=O)=O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CN3CCNC(c4ccccc4)C3)c2)cc1 +CC(C)CCC(=O)N(C)Cc1ccccc1-c1ccc(CN2CC(C)NC(C)C2)cc1 +CC1CCCN1CCc1ccc(-c2ccc(CCC(=O)NC(C)(C)C(=O)OC(C)(C)C)cc2)cc1 +CC(C)C(NC(=O)C(CC(=O)O)NC(=O)CCCOc1ccc(C(=N)N)cc1)C(=O)N1CCN(C)CC1 +CCCCc1nc2cc(OC)c(OC)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cccc(C(CCc2ccccc2)NCC(O)Cc2ccc(O)c(NS(C)(=O)=O)c2)c1 +Cn1c(-c2ccc(Cl)cc2F)nnc1-c1ccccc1C(F)(F)F +O=S(=O)(Nc1ccc(Br)cc1)c1ccc2c(c1)CNC(CF)C2 +O=C(CC1C(=O)NCCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1)NC1CCCc2cc(CN3CCCCC3)ccc21 +C#CCNc1ncnc2c(Nc3ccccc3C)nc(N3CCNCC3)nc12 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NCc1cc(Cl)ccc1Cl +COc1cccc(C(=O)N(C)N=Cc2ccc(OC)c(OC)c2)c1 +CCCC(c1cc(C(C)(C)C)c(O)cc1C)c1cc(C(C)(C)C)c(O)cc1C +CCCCNc1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#CC=NOCCN1CCOCC1 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(CCN5CCCC5)CC4)cc2)CC3)cc1 +CCN(Cc1ccncc1)C(=O)Cn1c(=O)n(C)c2cnc(-c3ccccc3)nc21 +C#Cc1cccc(Nc2ncnc3ccc(OCc4ccc(C(=O)Nc5ccccc5N)cc4)cc23)c1 +CNCC(Nc1ncnc2c(C(N)=O)cc(-c3ccc(C)cc3)cc12)C1=CCCC=C1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)c1cccn(-c2ccc(F)cc2)c1=O +Cc1ccc(-c2c[nH]c(C3(NCCc4c[nH]c5ccccc45)CCCC3)n2)cc1 +Cc1n[nH]cc1-c1cccc2c1CCC2c1ncc[nH]1 +COc1cc(-c2nnc3n(C(C)c4ccc(F)cc4)cc(CF)cc2-3)ccc1-n1cnc(C)c1 +Cc1ccc(O)c(C2C(=O)NC(=O)N2c2ccc3[nH]cnc3c2)c1 +COc1cc(CN(CC2CCCCC2)C(C)c2ccc3c(c2)CCO3)ccc1OCCN1C(=O)CCC1=O +O=C(CN1CCOc2ccccc21)N1CCN(c2scnc2-c2nc3ccccc3[nH]2)CC1 +CCC(C)C(NCC(N)CS)C(=O)NCc1ccc(C)cc1C +N#Cc1ccc(OCc2ccsc2)cc1OC(C(=O)O)c1ccccc1Br +CCCCCNC(=O)Nc1cc(C=CC(=O)NO)ccc1SCCN(CC)CC +COc1ccccc1CC1=C(Nc2ccc(C3=NNC(=O)CC3C)cc2)CCCC1=O +OC(CNC1CCC(C(c2ccccc2)c2ccccc2)NC1)c1ccc(F)cc1 +CN1C(C(=O)NC(C=O)Cc2ccccc2)Cc2cc(F)ccc2S1(=O)=O +CC(CC(=O)O)N1CC(=O)N(C(C)(C)C)c2c(Cl)cc(C#Cc3ccc(C(=N)N)cc3)cc2C1=O +O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c2ccccc12 +CC(C)C(C(=O)NC1CCC2CN(Cc3cccc(C(F)(F)F)c3)CC21)c1ccccc1 +CC(CC(N)=O)NC(c1ccc(Cl)c(C(=O)c2ccc(CO)cc2)c1F)C1CC1 +CCC1c2c(CO)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 +CC(C)(O)CNc1ncc(C(=O)NC2C3CC4CC2CC(O)(C4)C3)c(C2CC2)n1 +CCCCN(c1cccc(-c2ccc(Cl)cc2)c1C)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(OC)c1Cl +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(C)c(C)ccc4c3=O)CC21 +CCCCCN(CCCCC)C(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1cnc2ccccc2c1 +CCOC(=O)c1ccc(-c2cc(=O)c3ccccc3o2)cc1 +CCCc1cnc(N2CCC(C3Cc4cc(C5=CCN(S(=O)(=O)CCCCO)CC5)cc(F)c4O3)CC2)nc1 +CCCCCC(O)C=CC1C(CC=CCCCC(=O)OC)C(=O)C(C)(C)C1O +Cc1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +C[N+](C)(C)CC(=O)Nc1ccc2nc(O)c3ccccc3c2c1 +COc1cccc(OC)c1-c1ccc(CC(N=C(NCc2ccccn2)C2CCN2S(=O)(=O)c2ccccc2)C(=O)O)cc1 +Cc1ccc(S(=O)(=O)NC(=O)Cc2ccc(NCC(C)NCC(O)c3cccc(Cl)c3)cc2)cc1 +N#Cc1cc(-c2n[nH]c(-c3ccnc(C#N)c3)n2)ccn1 +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(NC2CCc3c(N)cccc32)C1 +O=C(NCc1ccc(N2C3CCCC2CC3)cc1C(F)(F)F)Nc1cccc2[nH]ncc12 +CC1=C(c2nc(-c3ccc(C#N)cc3)cs2)C(c2ccc(C(F)(F)F)nc2)NC(=O)N1 +CCCCc1nnc(S(C)(=O)=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1cc(OCC(=O)Nc2cc(-n3nc(C)cc3C)nc(-c3ccc(C)o3)n2)cc(C)n1 +CSc1[nH]c2cccc3c2c1CC1C3C=C(CO)CN1C +CN1c2ccccc2C(NCCCCCCC(=O)NCCCCNc2c3c(nc4ccccc24)CCCC3)c2ccc(Cl)cc2S1(=O)=O +CC(C)C(C)Nc1ccc(C(=O)O)cc1[N+](=O)[O-] +Cc1nccn2c(-c3ccnc(NCC(C)(C)C(=O)O)n3)c(-c3ccc(F)cc3F)nc12 +COCC(C)(O)CC1(c2ccccc2)CCN(C(C)c2ccc(-c3ccn(C)c(=O)c3)cc2)C(=O)O1 +Cc1cccc(-c2nc(Nc3ccncn3)c3ccccc3n2)n1 +Cc1ccc(C2=CC(c3ccc(N(C)C)cc3)n3nnnc3N2)cc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1cnc(C(C)(F)F)c(Cl)c1 +Cc1c(C)n(C(C)c2ccccc2)c2nc(-c3cnccn3)nc(N)c12 +N#Cc1ccc(OCc2ccc(F)cc2F)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 +Cc1ccccc1OCc1ccnc2c1NC(=O)c1cccnc1N2C1CC1 +O=C(CN1CCC(N2C(=O)OCc3cc(Cl)ccc32)CC1)Nc1ccc2c(c1)-c1ccccc1C2=O +CN(C)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 +CCCCN(C)Cc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +CCC(C)C(CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1)NC(C)=O +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)C(N)C(C)C)CC2)cc1 +COc1cc(OCc2csc(-c3ccc(OC(F)(F)F)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +C=CC(=O)NCCCn1c(NC(=O)c2cccc(C(F)(F)F)c2)nc2cc(C)ccc21 +CCn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +O=C(N1CCC(CCSc2ncc[nH]2)CC1)C12CC3CC(CC(C3)C1)C2 +CCC(C)C(NCN(Cc1ccc(F)cc1)C(=O)c1ccc(F)cc1)C(=O)NC(Cc1cscn1)C(=O)NO +CC(=O)N1CCc2c(nc(C)n2C2CC3CCC(C2)N3CCCN(C(=O)Nc2ccc(F)cc2)c2ccccc2)C1 +Cc1ccc(S(=O)(=O)Nc2c(C(=O)NCc3ccc(C)cc3C)cnn2-c2ccccc2)cc1 +CN1CC(C(=O)N2CCC(C)(N3CCc4c(-c5cnc(N)nc5)nc(N5CCOCC5)nc43)C2)C1 +NC1CCN(C2CCC(NC3CC3c3ccc(-c4cccc(C(F)(F)F)c4)cc3)CC2)C1 +CCc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)cc12 +OC(c1ccc(Cl)cc1)(c1cccnc1)c1cnc(OC(CF)CF)nc1 +[N-]=[N+]=NCCCCCCCCCCCC(=O)OCC1OC(n2ccc(N)nc2=O)CS1 +CCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]nc(C)c2c1)c1ccccc1 +Cc1ccc2ccccc2c1-n1c(C)nc2ccc(O)nc21 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(-c2ccccc2)c1 +CC(=O)c1ccc(N2CCN(C(=O)c3ccc(NC(=O)N4Cc5ccccc5C4)cc3)CC2)cc1 +C=CCNC(=O)OC(C)C1c2ccccc2-c2c3c(c4c([nH]c5ccccc54)c21)CNC3=O +Nc1ncnc2c1nc(Sc1ccc(Cl)cc1)n2C1OC2COP(=O)(O)OC2C1O +O=C(Nc1ccncc1)Nc1ccc(CCN2CCN(c3ccccc3)CC2)cc1 +Cc1c(OCc2cccnc2)ccc2c(N3CCNCC3)cc(=O)oc12 +CC1CN2c3c(cc4c(-c5nccnc5Cl)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +Cc1[nH]c2ccccc2c1CN(C)C(=O)C=Cc1cnc2c(c1)CCC(=O)N2 +CC(=O)Nc1ccc(-c2cccc(C(C)NC(=O)C3=C(O)C(=O)N(c4ccc(F)cc4F)C3)c2)cc1 +OC1OC(n2cnc3c(NC4CCCCC4)ncnc32)C(O)C1O +Cc1ccc(C(=O)NCCCOc2ccc(S(=O)(=O)C3(C(=O)NO)CCOCC3)cc2)c(C)c1 +CC(Oc1cccc(Cl)c1)C(=O)N(Cc1cccc(Cl)c1)CC1CCCN1 +Oc1ccc(C=Cc2cnc(OCCOCCOCCF)c(I)c2)cc1 +Cc1ccc(S(=O)(=O)n2cc(C(=O)C(=O)NCC(=O)O)c3ccccc32)cc1 +COc1cccc(-c2nc3c(c(Nc4ccc(CC(=O)O)cc4)n2)SCCC3)c1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(C(F)(F)F)cc1-c1ccncn1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(CC(C)C)C(=O)N1CCCC1B(O)O +CCOC(=O)c1ccc(NC(=O)NC(Cc2ccc(O)cc2)C(=O)NC2CCN(Cc3cccc(C#N)c3)C2)cc1 +CN1CCC(F)(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CC1 +c1cnc2c(N3CCN(CCCCc4ccc(OCCCN5CCCCCC5)cc4)CC3)cccc2c1 +CC1c2c(ccc(O)c2F)OC(c2ccc(OCCN3CCCCC3)cc2)C1c1ccc(O)cc1 +O=c1cc(N2CCc3[nH]nc(-c4ccncc4)c3C2)ccn1Cc1cccc(F)c1 +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)Nc1cccc2cccnc12 +CC(C)(C)c1cc(NC(=O)Nc2ccc(N)cc2)n(-c2ccccc2)n1 +COc1cc2c(Nc3ccc(F)c(Cl)c3)c(C(N)=O)cnc2cc1OCCN(C)C +CC1SCc2ncnc(N3CCN(C(=O)C(N)Cc4ccc(F)cc4)CC3)c21 +CC(=NNC(=O)c1cc(Br)ccc1O)c1cc2c(F)c(F)ccc2[nH]1 +CCN(CC)c1ncnc2[nH]cc(-c3cccc(C#N)c3)c12 +Clc1ccc2nc(NCCc3ccc(NC4=NCCCS4)cc3)sc2c1 +Nc1ncnc2c1sc1nc(C3CC3)cc(C(F)(F)F)c12 +CN(Cc1ccc2nccnc2c1)C(=O)c1ccc(C(=O)C(F)(F)F)s1 +Oc1ccc2oc(-c3cccc(Cl)c3)cc2c1CN1CCC(N2CCCCC2)CC1 +COc1cccc(-c2[nH]c(-c3ccccc3)nc2-c2ccncc2)c1 +O=C(CCn1c2c(c(=O)[nH]c1=O)CCCC2)NCC(=O)c1ccc2ccccc2c1 +CC(=O)N(c1ccccc1)C1CC(C)N(C(=O)C=Cc2ccccc2)c2ccccc21 +CC(C(=O)NN=C1C(=O)Nc2ccc(C(=O)N3CCC(NC4CC4)CC3)c(Cl)c21)c1ccc(O)cc1 +O=C1CCCc2cc(Nc3cc(C(F)(F)F)ccn3)ccc2N1 +CC(CO)Nc1cc(NS(=O)(=O)c2ccc(C#N)cc2)nc(SCc2ccccc2)n1 +Fc1ccc(C#CCOc2nsnc2C23CN4CC2C3C4)cc1 +O=C1NC(=S)SC1=Cc1csc(-c2ccccc2O)n1 +CN(C)C(=O)c1nc(Nc2cccnc2Oc2ccccc2C(C)(C)C)sc1-c1ccccc1 +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(NCCc3ccccn3)nc2c1 +O=C(Nc1ccc(F)cc1)Nc1ccc(CNc2nc3ccc(OCCN4CCOCC4)cc3s2)cc1 +OC1COc2cccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 +Cn1cc(-c2cc(C(=O)Nc3nccs3)ccc2Oc2ccccc2)c2cc[nH]c2c1=O +O=C1CCc2ccc(NC(=O)NC3CCOc4cc(OC(F)(F)F)ccc43)cc2N1 +CCC(CO)Nc1nc(Nc2cccc(Cl)c2)c2ncn(C(C)C)c2n1 +Cc1cnccc1CCC(C)C1CCC2C34CCC5(CC(N(C)C)CC=C5C=C3CCC12C)O4 +CC(C)Nc1c([N+](=O)[O-])cnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12 +CCn1cc(Nc2nccc(-c3ccn(C(CO)c4ccc(Cl)c(F)c4)c(=O)c3)n2)c(C)n1 +COc1ccc(S(=O)(=O)N(Cc2ccc(-c3nnn[nH]3)c(F)c2)Cc2ccccn2)cc1 +COCC(C)Oc1cc(C=Cc2cccc([N+](=O)[O-])c2)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CO)Cc1ccccc1 +Cc1nc2cc3c(cc2[nH]1)C1(C)CCN(CC2CC2)C(C3)C1C +O=C(CSc1nc2c(c(=O)n1-c1ccccc1)SCC2)Nc1ncc(-c2ccco2)cn1 +N#Cc1cn(-c2c[nH]n(-c3cc(N4CCCOCC4)ncn3)c2=O)nn1 +CC(C)(C)c1ccc(CNC(=O)c2cn3cc(-c4ccc(C5CCC(CC(=O)O)CC5)cc4)ccc3n2)cc1 +Cc1ccnn1CC12CNCCC1(c1ccc(Cl)c(Cl)c1)C2 +CNc1ccc(C=Cc2ccc(OCCCCCCCCCCCCCCCCCCCCCCCCF)cc2)cc1 +CCN(Cc1ccc(-c2cc(OC(C)C3CNC(=O)C3)c3cccnc3c2)cc1)C(C)=O +CN1CC=C(c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Br)oc23)CC1 +COc1cc2c(-c3ccc(O)cc3)nc3c(c(C)nn3-c3ccccc3)c2cc1OC +COC(=O)N1CCN(C(=O)Cc2ccc(F)c(Cl)c2)C2C(N3CCC(F)C3)CCCC21 +Cc1ccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)cc1C +CC(C)(Oc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2)C(N)=O +COc1cc(Nc2nc3n(n2)CCCN3CCC2CC2)ccc1-n1cnc(C)c1 +CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)cc21)C(=O)C1CC1 +O=C(NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21)c1ccccc1 +CCOC(=O)c1ncn2c1Cn1ncnc1-c1cc(C3CC3)ccc1-2 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCc3ccncn3)[nH]c3ccc(Cl)cc23)c1 +CC1=CC(=O)N(Nc2nc(-c3cccs3)nc3scc(-c4ccccc4)c23)C1=O +COc1cccc(C#N)c1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 +COc1ccnc(Nc2nc(-c3sc(C)nc3C)cs2)c1 +Cc1cnn(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C)n2)n1 +NC1(c2ccc(-c3nc4nc(OCCN5C(=O)c6ccccc6C5=O)ccn4c3-c3ccccc3)cc2)CCC1 +ON=C(c1ccc(Sc2cc(F)cc(C3CCOCC3)c2)cc1)C(F)(F)F +CC(=O)NC1C(NC(=N)NC(=O)CSc2cccc3ccccc23)C=C(C(=O)O)OC1C(O)C(O)CO +CC(C)S(=O)(=O)NC1COCC1c1ccc(-c2ccsc2)cc1 +C=CCn1c(=O)c2[nH]c(-c3ccccc3)nc2n(C)c1=O +CC(CCC(=O)NCCc1ccc(S(N)(=O)=O)cc1)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C +CN1CCN(CCn2cc(CNc3c4ccccc4nc4c3oc3ccccc34)nn2)CC1 +O=c1cc(NCc2ccc(C(F)(F)F)cn2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 +NC1=NC(c2ccncc2)(c2cccc(-c3cncnc3)c2)C2=NCCCN12 +COC(=O)COc1ccc2oc(=O)n(Cc3ccc(Cc4ccc(I)cc4)cc3)c2c1 +CC1(c2cc(NC(=O)c3ccc(Cl)cn3)cc(C(F)(F)F)c2)CCSC(N)=N1 +CCOc1c(Cl)cc(Cl)cc1CNCCCNc1nc(O)c2ccccc2n1 +Cn1cc(Nc2ncc(Cl)c(CCc3ccccc3C(C)(C)C(N)=O)n2)cn1 +O=C(Cc1ccncc1)N1CCN(C2c3ccc(Cl)cc3SCc3cccnc32)CC1 +CC(O)CN(CC(O)C(Cc1ccccc1)NC(=O)CC1C=CCC1)S(=O)(=O)c1ccco1 +Cc1cccc(Nc2ccc(C#N)cc2S(=O)(=O)NC(=O)NC(C)(C)C)c1 +CNc1cc(NC(=O)OC)ccc1Nc1c2c(nc3c1C=CCC3(C)C)CC(C)(C)C=C2 +COc1cc2ncnc(Nc3ccc4c(c3F)CCN4C(=O)Cc3c(C)[nH]c4ccccc34)c2cc1OC +CCCc1cc(OC)c(OC)c(C(=O)NCC2CCCN2CC)c1O +FCCc1ccc(-c2cn(C3CN4CCC3CC4)nn2)cc1 +CCCN=C1SC(=Cc2ccc(OCCO)c(Cl)c2)C(=O)N1c1ccccc1C +CCC(C)C1NCCOc2ccccc2CCCNC(=O)C(Cc2ccccc2)NC(=O)C(C)N(CC)C1=O +CN1CC(CNC(=O)c2ccccc2)CC2c3ccc(C(C)(C)C)c4[nH]cc(c34)CC21 +CCCS(=O)(=O)c1nccc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)n1 +COc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2cccc(C(F)(F)F)c2)CC1 +CC(c1ccc(-c2ccc(C#N)cn2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2)OC1=O +Cc1cc(OCCN2CCCCCC2)nn1-c1ccc(Cl)c(Cl)c1 +N=C(Nc1cccc2ccccc12)N(c1ccccc1)c1cccc2ccccc12 +Cc1ccc(-c2noc(COc3ccc(CCC(=O)O)cc3)n2)cc1 +CCN1CCCC1CNC(=O)c1ccc(-c2cnc3ccc(NCC4CC4)nn23)cc1 +COc1ccc(N2C(=O)C(=Cc3ccc(O)c(Br)n3)OC2=S)cc1 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+N=C(N)NOCCNC(=O)Cc1c(Cl)ccc(NCC(F)(F)c2cccc3cnccc23)c1F +Cn1cc(-c2cnc3nnn(Cc4ccc5ncncc5c4)c3n2)cn1 +COc1ccc2c(c1)C(=O)N(CCc1ccc(S(=O)(=O)NC(=O)NC3CCCCC3)cc1)C(=O)C2(C)C +CCCCCCCOc1ccc(CCC(=O)OCC(O)COP(=O)(O)OCC(N)C(=O)O)cc1 +NC(=O)c1ccc2[nH]c(-c3ccc4[nH]c(-c5ccc6ccccc6c5)nc4c3)nc2c1 +OCCN1CCCC(c2nc3ccccc3n2Cc2ccc(F)cc2)C1 +O=C(Cc1ccccc1)NCc1ccc(-c2nc(C(=O)N3CCC(Cl)CC3)co2)cc1 +OC(CNC1CCC(C(c2ccccc2)c2ccccc2)OC1)c1ccc(F)cc1 +COCCN(Cc1ccccc1)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +CC(C)c1ncc(COCCCCCC#N)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +Nc1ccccc1NC(=O)c1ccc(CSC2=NC(c3cccnc3)CO2)cc1 +CNC(=O)c1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(CCOC)c4)nc3c2)c1 +NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1cccc(NS(=O)(=O)N2CCCC2)c1 +COc1cc(CN2CC(C)OC(C)C2)cc2[nH]c(=O)c3c(c12)NCCC3 +O=C1CCc2ccccc2N1CCCN1CCC(c2ccc3[nH]ccc3c2)CC1 +O=C(Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1)c1cc(F)cc(C(F)(F)F)c1 +Cc1cc(NC(=O)c2ccc3cc4n(c3c2)C(C)CNC4=O)no1 +O=C(NCc1ccccc1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +Cc1nn(C)c2c1CN(c1ncnn3c(C)nc(C4CCOCC4)c13)CC2 +CS(=O)(=O)c1ccc(-n2nc(COc3ccc4c(c3)OCO4)cc2-c2ccccc2)cc1 +CCC1(CC)CNC(=O)c2cc(-c3ccncc3)[nH]c21 +CCCCn1cc[n+](CC(O)(P(=O)([O-])O)P(=O)(O)O)c1 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN(Cc2cccnc2)C(=O)c2ccccc2)cc1 +Oc1ccc(Nc2nc(-c3ccccc3)nc3ncccc23)cc1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3cc4ccccc4[nH]3)CC2)nc1 +COc1ccc(-c2ccc3c(O)oc(=O)c(C(=O)NCC(=O)O)c3c2)cc1 +CS(=O)(=O)c1ccc2c(c1)CCN2CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CN1Cc2cc(-c3ccc(CC(C#N)NC(=O)C4CCCCN4)cc3)ccc2C1=O +COc1cc(NC(C)CCCNC2CCC3(CC2)OOC2(C)CCC(C(C)C)=CC2O3)c2ncccc2c1 +Oc1ccc2c(c1)sc1c3cc(O)ccc3n(Cc3ccc(OCCN4CCOCC4)cc3)c21 +CC(NC1CCC(N)CC1)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +CC1COCc2[nH]c(-c3cc(C(=O)N4CCC(c5ccc(C#N)cc5)CC4)ccc3C3CC3)nc21 +CC(=O)NCc1ccccc1-c1ccc(COC2CCC(N3CCCCCC3)C2OCC=CCCC(=O)O)cc1 +CCCC1CC(OC)CC(C)=CC2CC(OC(=O)C(C)=CCCc3coc(C=CCNC(=O)OC)n3)CC(CC(=O)O1)O2 +O=C(NC1CCOCC1O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=c1oc2cc(O)ccc2c(-c2ccc(OCCN3CCCCC3)cc2)c1-c1ccccc1 +c1ccc2c(CCNc3ccc(CN4CCOCC4)cc3)c[nH]c2c1 +Cc1cccc(NC(=O)Nc2ccc(S(=O)(=O)Nc3ccc(CC(C)(C)N)cc3)cc2)c1 +Cc1nnn(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)c1NC(=O)OC(C)c1ccccc1 +CC1CN(C(C)CO)C(=O)c2cc(NC(=O)NC3CCCCC3)ccc2OC1CN(C)S(=O)(=O)c1ccc(Cl)cc1 +Cc1cccc(-c2nn(CC(=O)Nc3cccc(C(N)=O)c3)cc2-c2ccc3ncccc3c2)n1 +COc1ccc2[nH]cc(CCNCCCc3ccccc3)c2c1 +COc1ccc(CN=C2NC(CO)C(O)C(O)C2O)cc1 +Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cnc(N(C)C3CCN(C)CC3)nc12 +CCC1(c2ccc(C)cc2)Oc2ccccc2-n2cccc2C1=O +Cc1cnc2c(C(=O)NC3C4CC5CC3CC(C#N)(C5)C4)cnn2c1 +COc1cc(Oc2ccc3c(N)c(OC)ccc3n2)cc(OC)c1OC +CCN(CC)CCOc1ccc2c(c1)C(C)(C)c1oc3cc(O)ccc3c1C2=O +CCNC(=O)Nc1ncnc2c1ncn2C1OC(CC(=O)O)C2OC(C=Cc3ccccc3)OC21 +O=C(c1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)c(F)c1)N1CCCC1 +Cn1c(-c2cnc(NC(=O)c3cccc(C#N)c3)s2)nc2ccccc21 +CCOC(=O)CNC(=O)C(=O)C(COCc1ccccc1)NC(=O)C(CC1CCCCC1)NC(=O)c1cc(SC)ccc1Cl +CNC(=O)c1cc(Oc2ccc3c(c2)CC(C(=O)Nc2ccc(CN)c(C(F)(F)F)c2)CC3)ccn1 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+O=C1N(Cc2ccc(Br)cc2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc(Br)cc1 +O=[N+]([O-])c1cn2c(n1)OCC(OCc1cccc(-c3ccc(F)cc3)n1)C2 +O=c1[nH]c(-c2ccc(S(=O)(=O)N(CCC3CC3)c3sc4ccccc4c3Cl)cc2)no1 +CC1(C)CC(=O)C2=C(C1)Nc1c(O)cccc1N(C(=O)c1cccnc1)C2c1ccc(OCc2ccccc2)cc1F +COc1c(C)cnc(Cn2cc(CCCO)c3c(Cl)nc(N)nc32)c1C +O=C(Nc1ccc(-n2cncn2)cc1)NC1CCCCC1CN1CCCC(Cc2ccc(F)cc2)C1 +CCc1[nH]c2nc(Sc3ccc4nccnc4c3)nc(N3CC4C(N)C4C3)c2c1Cl +CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C(C)C)C2 +CCCON1C(=O)C(NC(=O)OCCCCC2CCCCC2)C1C +COc1cccc(NC(=O)N2CCNCC2COc2cccnc2)c1 +CC#CCOc1ccc(S(=O)(=O)N2CC(CC(=O)O)SC(C)(C)C2C(=O)NO)cc1 +Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3CC(=O)NC3=O)cc12 +NC(=O)n1cc(NC(=O)N2CC(N)CC2C(=O)NCc2cccc(Br)c2)c2ccccc21 +COc1cc(N2CCN(C)CC2)c2[nH]c(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1 +COc1cc(F)c(-n2c(=O)[nH]c3csc(C(=O)O)c3c2=O)cc1CN(C)c1c(F)cccc1F +CC(=O)Nc1ccc(S(=O)(=O)NNc2cc(Cl)cc(Cl)c2)cc1 +COc1cc(-c2cnn(C)c2CO)ccc1Nc1ncc2ccnc(NCC3(C)CCOC3)c2n1 +CNc1ccc(C(=O)NCCCCCC(=O)Nc2ccccc2N)cc1 +O=P(O)(O)C(CCCc1cccc(Oc2ccc(Cl)c(Cl)c2)c1)S(=O)(=O)O +CN(CCO)CCc1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(Cl)cn1 +CN(C(=O)Cc1ccccc1)C(Cc1ccc2ccccc2c1)NC(=O)C1CCCCC1NC(=O)c1c[nH]c2ccccc12 +O=C(NC1CCC(N2CCOCC2)CC1)c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1 +COc1cc2ccccc2cc1C=NNC(=O)c1cc(O)c(O)c(O)c1 +CC1CN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CCN1c1nsc2ccccc12 +O=C(CC1NCCCC1O)Cn1cnc2cc(Br)c(Cl)cc2c1=O +O=C(O)CN1CN(Cc2ccc(C(F)(F)F)cc2)S(=O)(=O)c2cc(Br)cnc21 +O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)N1CCCCC1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C(=O)NC1CCOCC1 +COc1ccc(CC(=O)NCC2CCCN(Cc3cc(OC)cc(OC)c3)C2)cc1 +CN1CCC(n2cc(Cn3cc(NC(=O)c4cnn5cccnc45)c(-c4cc(Cl)ccc4OC(F)F)n3)nn2)CC1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3nnco3)cc2)c1C +CON=C1CC(C)(C)Nc2cc(F)c(-c3cccc4cc[nH]c34)c(F)c21 +O=C(NC1CC1)c1ccc(-c2cnn3c(NCCN4CCOCC4)nc(Oc4ccccc4)nc23)cc1 +CN1CCN(c2nc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)ns2)CC1 +CC1=CCC2C(C1)c1c(O)cc(CC#CCCO)cc1OC2(C)C +O=C(Nc1ccc(-c2ccc(C(=O)C3CCCC3C(=O)O)cc2)cc1)Nc1ccc(C(F)(F)F)cc1 +NC(=O)c1cccc2c(NCc3ccc(C(F)(F)F)cc3)ncnc12 +Cc1nc2cc(-n3ncc(C(=O)c4cc5cc(C(F)(F)F)ccc5[nH]4)c3N)ccc2[nH]1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(NC(C)c4cccnc4)n3)cccc2s1 +CCCCCCNc1nccc(-c2c(-c3ccc(F)cc3)nc3cc(CN(C)C)ccn23)n1 +Cc1cc(=O)c2c(O)cc(O)c(C3CCN(C)CC3O)c2o1 +COC1CCC2(CC1)Cc1ccc(CCC3CC3)cc1C21N=C(N)N(Cc2ccc(S(C)(=O)=O)cc2)C1=O +CCB(CC)OC(=O)C(N)CCCCNC(=S)NCCc1ccc(S(N)(=O)=O)cc1 +NS(=O)(=O)c1c(F)c(F)c(-n2cc(CCCCCl)nn2)c(F)c1F +COc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2)c1 +CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 +CC(C)CN1CCC([S+]([O-])c2ccc(CNC(=O)c3cc4ccncc4o3)nc2)CC1 +Cc1c(N(Cc2ccccc2)S(=O)(=O)c2ccc(F)c(F)c2)sc2ccccc12 +O=C(O)c1ccc2c(c1)nc(NCc1ccccc1)c1ccncc12 +COc1ccc(N2CCN(CCCNC(=O)Cn3c(=O)c4cccn4c4cccnc43)CC2)c(OC)c1 +CCNCCNc1cc(-c2cccc(C(F)(F)F)c2)c(C#N)c2nc3ccccc3n12 +Cc1ccc(C2CC2COc2nc(C)ncc2-c2nn(C)c(=O)cc2C)nc1 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+O=S(=O)(NCC1CCC(Nc2nc3c(s2)CCSc2ccccc2-3)CC1)c1cccc2ccccc12 +CCc1cc2c(cc1N1CCC(O)(C3CC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CC(C)Nc1nc(-c2ccc(C(C)(C)C#N)cc2)cc2ncn(C)c(=O)c12 +CCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1nc2cc(OC)cc(OC)c2c(=O)[nH]1 +CCC(C)Nc1cc(C(=O)NC2CC3CCC(C2)N3c2ccc(C(=O)C3CC3)cn2)c(C)cc1C(N)=O +O=C(Nc1ccc(F)c(-c2nc3cc(-c4ccccc4Cl)cnc3[nH]2)c1)N1CCCC1 +Cn1ccc2nc(COc3ccc(-c4ccc(=O)[nH]c4-c4ccc(Cl)cc4)cc3)ccc21 +Cc1ccc(C(=CCNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(C)cc2)cc1 +CC1NC(=O)c2cc(-c3c(F)ccc4c(=O)n(C)c(NC(C)(C)C)nc34)[nH]c21 +CCOC(=O)c1cnc(N(C)N2C(=O)C=C(C)C2=O)nc1C(F)(F)F +Cc1ccc(NC(=O)c2cccc(N3CCOCC3)c2)cc1NC(=O)c1ccc(OCc2cccnc2)cc1 +O=C(O)CCNC(=O)c1ccc(-c2cc(C(F)(F)F)ccc2CNc2ccc(-c3ccc(Cl)cc3F)cc2)cn1 +O=C(Nc1ccccc1F)c1ccc(Nc2nc(Nc3ccc(O)cc3)ncc2F)cc1 +COc1ccc(-c2c(-c3cc(OC)c(OC)c(OC)c3)ncn2C)cc1N +CCc1cccc(NC(=O)N2CCc3nc(-c4c(C)noc4C)nc(-c4ccccc4C)c3C2)c1 +COc1ccc(S(=O)(=O)NCC2(c3cccc4ccccc34)CC2)cc1N1CCN(C)CC1 +C#CC1(O)CCC2C3CCC4CC(F)(F)CCC4(C)C3CCC21C 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+COc1ccccc1N1CCN(CCCc2cn(-c3ccc(N(C)C)cc3)nn2)CC1 +Cc1cc(Nc2ccccc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +Cn1cc2c(nc(NC(=O)NC3CCN(Cc4ccccc4)CC3)n3nc(-c4ccco4)nc23)n1 +Fc1cnccc1-c1cc(-c2ccc(F)c(-c3ncccc3F)c2)cnn1 +CC(C)CC(NC(=O)C1(c2ccccc2)CC1CN1CCC2(C)c3cc(O)ccc3CC1C2C)C(=O)NCCCCCCN +O=C(NCc1ccc(Cl)cc1Cl)Nc1cccc2ccc(O)cc12 +O=C(NC1CC1)C1OC(n2cnc3c(NCCc4cn(CCN5CCCCC5)c5ccccc45)ncnc32)C(O)C1O +O=C(CCCn1c(=S)[nH]c2ccccc2c1=O)N1CCC(c2ccccc2)CC1 +COc1cc(C2=NCC(=O)N3CCc4c(I)cccc4C3=C2)ccn1 +CC1CN(Cc2ccc(C(C)Nc3ncc(F)c(N4C(=O)OCC4C(C)C)n3)cc2)CC(C)O1 +Fc1ccc(OCCCN2CCN(c3ncc(F)cn3)CC2)cc1 +Cc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CC(=O)Nc1nc2ccc(-c3nn(Cc4cc5cccc(C)c5c(=O)n4C4CC4)c4ncnc(N)c34)cc2s1 +CNCc1cc(C(=O)N2CCN(C3CC3)CC2)ccc1Oc1ccccc1 +Nc1ncc(-c2cc(C3CC4CCC(C3)N4CC(F)(F)F)nc(N3CC4CC3C4)n2)cn1 +COc1ccc(C2N(c3ccnc(NC(C)c4ccccc4)n3)C(=O)OC2(C)C)cc1 +CC(C)(C)c1ccc(O)c(C(=O)Nc2ccc(CN)cc2)c1 +COc1ccc(C(=O)N2CCC(N3CC(CC#N)(n4cc(-c5ncnc6[nH]ccc56)cn4)C3)CC2)cc1C#N 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+O=c1c2c(oc(O)c1C(c1ccccc1)C1CC1)CCCCCCC2 +COc1ccc(S(=O)(=O)N2CCN(C(S)=NCc3ccccc3)CC2C(=O)NO)cc1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2C)cc1-c1ccc2nc(NCCN3CCCCC3)ncc2c1 +COc1ccc(COC2CC3C(C2C)C2OC(=O)C(C)C24C=CC3(C)OO4)cc1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)c(-c3ccccc3)cc21 +CCCCCCCCC=CCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2cccnc2)cc1 +O=C(Nc1cc2ccc(-c3ccc[nH]3)cc2cn1)C1CC1 +O=C(O)c1ccc(-c2ccc3c(c2)CC(NCC(O)c2cccc(Cl)c2)CC3)cc1 +CN1CCC(=O)N=C1NC(=O)Nc1cccc(C#N)c1 +Cc1cc(NC(=O)Nc2ccc(F)c(F)c2)n(CC(F)(F)F)n1 +O=C(COc1cccc2c1CCCN2Cc1ccccc1)NCC(O)CN1CCc2ccccc2C1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1Nc1cnn(CCCF)c1 +O=C(Nc1ccccc1)c1ccc(OCCCN2CCCC2)cc1OCc1ccccc1 +O=S(=O)(c1ccccc1)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)CC2(CN2CCCCC2)C1 +CCCN(CCC)C1CCc2c(ccc(C(O)Cc3ccc(Cl)c(Cl)c3)c2OC)C1 +CC(C)N(CCOc1ccc(-c2oc3nccc(NCCN4CCNCC4)c3c2-c2ccccc2)cc1)C(C)C +CCN(CC)c1ccc2cc(NC(=O)CCc3ccc(C(F)(F)F)cc3)ccc2n1 +CC(Oc1ccccc1)C(=O)N(Cc1ccc(Cl)cc1)CC1CCCN1 +Nc1ncnn2ccc(C(=O)Nc3cccc(CNC(=O)Nc4cccc(F)c4)c3)c12 +CCC(CNC(=O)NCCCCNC(=O)NCC(CC)C12CC3CC(CC(C3)C1)C2)C12CC3CC(CC(C3)C1)C2 +CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCC(N)C4)cn3)nc2n(C2CCCC2)c1=O +N#CC1CC(NCC(F)(F)F)CCC1n1cc(C(N)=O)c(Nc2ccnc(F)c2)n1 +CCCCCCCCCCCCCCCCCCCCOC1CC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CO1 +O=Nc1c(-c2c(O)[nH]c3ccc([N+](=O)[O-])cc23)[nH]c2ccccc12 +CCS(=O)(=O)Nc1cc(F)cc(CNc2ccc(Cc3c[nH]c4ncc(C)cc34)c(F)n2)c1 +O=C(Nc1c(O)cccc1-c1nc2c(C(=O)O)cccc2o1)c1cc(-c2ccccc2)on1 +O=C(C1CCCNC1)N1CCN(c2nccc(NCc3ccc(Cl)cc3Cl)n2)CC1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F +CN(C)Cc1cc(CNS(C)(=O)=O)ccc1Oc1ccc(OC(F)(F)F)cc1 +CC(C)(C)c1nc(C2CC2)cc(N2CCN(CCCCNC(=O)c3cn4ccccc4n3)CC2)n1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4cccs4)s3)c2)C(O)C(O)C1O +N#Cc1nc(CCCN2CCC(O)CC2)cc(-c2cccc(C(F)(F)F)c2)n1 +Cc1cccc(Nc2cc(CN(Cc3ccccc3C(F)(F)F)CC3CCCCC3)nn2C)c1C +COc1cc(-c2nc(-c3ccnc(C)c3)c3n2CC(C)OCC3)ccc1OC(F)(F)F +CC1=CCC2C(C1)c1c(O)cc(C(C)(C)c3cccc(C#N)c3)cc1OC2(C)C +Nc1nc(O)c2c(n1)NCC(CCNc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)N2 +CS(=O)(=O)c1ccc(-c2ccc(CNC(=O)c3ccc(OCCC(F)(F)F)nc3)cc2)cc1 +CCOc1cnc(N2CCN(c3noc(C(C)(F)F)n3)C(C)C2)c(C)c1 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1(C)CCN(C(=O)C(F)(F)CN)C1)CC2 +NC1CN(c2ccc3nc(=O)ccn3n2)CCC1c1cc(F)c(F)cc1F +Cc1cc(-c2nc3cc(Cl)cnc3n2Cc2ccccc2)cn(C)c1=O +COCCCC(CC(=O)O)N1CCc2cc(OCc3ccc(C(=N)N)cc3)ccc2C1=O +O=C(C#CCO)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +Fc1ccc(F)c(OC(c2ccccc2)C2CCNC2)c1Cl +CCCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCCC2CNS(=O)(=O)c2cccc(Cl)c2)n1 +CCN1CCN(C2CCC(NC(=O)c3cc4c(C)nn(C5CCOCC5)c4s3)CC2)CC1=O +Cc1ccc(C2C3=C(CCCC3=O)NC3=C2S(=O)(=O)CC3)cc1I +O=C(CCc1ccc(-c2ccc(O)cc2Cl)s1)Nc1ccccc1C(=O)O +CONC(=O)c1cnn2ccc(N3CCCC3c3cc(F)cnc3CO)nc12 +Cn1c(CNc2ccc(C(=N)N)cc2F)nc2cc(C(=O)N(CCC(=O)O)c3ccc(F)c(Cl)c3)ccc21 +CCc1nccc(-c2ccc(C(=O)NCCOC)c(F)c2)c1C#Cc1ccc(N)nc1 +Cc1ccc(-n2ncccc2=O)cc1NC(=O)C1=CN(C)C(=O)CC1c1ccc(F)cc1 +CCc1ccc(Cc2sc(C3OC(CO)C(O)C(O)C3O)nc2Br)cc1 +CNc1ccc(-c2ccc(C(=O)NC(CO)CC(C)C)cc2C(=O)O)c(C(=O)Nc2cccc(C(N)=O)c2)c1 +COc1ccc2c(c1)C(CNC(C)=O)Cc1ccccc1C2 +Cn1nc(C(F)(F)F)cc1-c1ccc(Oc2cc(F)c(S(=O)(=O)Nc3nccs3)cc2Cl)c(C#N)c1 +CC(=O)OCCCCC(C1=C(C)C(=O)C(C)=C(C)C1=O)c1cccnc1 +O=C(CCCCO)CCCCCCCC(O)C1NC(CO)C(O)C1O +COC(=O)c1ccc(Cc2n[nH]c(=O)c3c2CCCC3)cn1 +CN(C)CCNc1nccn2c(-c3ccncc3)c(-c3ccccc3)nc12 +Cc1cc(Cl)ccc1-c1cccc(COc2ccc(C(CC(=O)O)c3nnnn3C)cc2)c1 +CCOC(=O)Nc1ccc2cc3ccc4c(c3nc2c1)COCN4 +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2cccc([N+](=O)[O-])c2)cc1 +COc1ccc2c(c1)c(CCN(O)C(N)=O)c(C)n2C(=O)c1ccc(Cl)cc1 +Cc1c(N(Cc2ccc(OCC3CCCC3)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +NC(=O)C12CC3CC(C1)C(NC(=O)c1cccc(NS(=O)(=O)c4cc(Cl)cc(Cl)c4)c1)C(C3)C2 +CSCC(NC(=O)C(Cc1ccccc1)OC(=O)N1CCC(N)CC1)C(=O)NC(CC1CCCCC1)C(O)CCSc1nccs1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)C(C)(C)C(=NNC(N)=O)CC2 +CCC(O)=C(C#N)C(=O)Nc1ccc(OS(=O)(=O)C(F)(F)F)cc1 +CNCC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +O=C(Cc1ccccn1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 +Cn1c(=O)c2c(nc3n2CCCN3CCc2cccc(Cl)c2)n(C)c1=O +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CC(S(C)(=O)=O)C4)ncn3)c2c1 +O=C1CC(N2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)CC2)N1 +CC(=O)N1CCN(C(=O)c2cc(Sc3cnc(Nc4cc(C)cc(C)n4)s3)ccc2O)CC1 +Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)Nc1ccc(N)cc1)c1nnc(C)n1-2 +Cc1nn(C(=O)c2[nH]nc(-c3ccc(Cl)cc3)c2N)c(C)c1Cl +O=C1Nc2ccc(S(=O)(=O)N3CCCC3COc3ccncc3)cc2C1=O +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(F)cc3)NC(=O)NC1=O)C2 +CC(C)(O)C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2 +CC1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)COCCC(N)=N1 +CN(CCCc1ccccc1)CCN(C)CCOC(c1ccc(F)cc1)c1ccc(F)cc1 +O=C1C(=CC=Cc2ccccc2)c2ccccc2N1Cc1ccccc1 +CCS(=O)(=O)c1ccc(S(=O)(=O)NC)cc1Nc1cc(Nc2ccc(Cl)cn2)ncn1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1 +CC(CN1CCC2(CC1)C(=O)NCN2c1ccccc1)NC(=O)c1ccc(F)c(F)c1 +COc1cccc2c1OC1(CCN(C)CC1)N1N=C(c3ccc(F)cc3)CC21 +COc1ccc(-c2[nH]c3ccc(C(C)C)cc3c2C=C(C#N)C#N)cc1 +CN(CCCN1c2ccccc2Oc2ccccc21)CCc1ccccc1 +CCCCN(CC)c1cc(C)nc2c(-c3ccc(OC)cc3OC)c(C)nn12 +CCCCCCCCC=CCCCCCCCC(=O)OCCCOP(=O)(O)OCC(N)C(=O)O +Cn1cc(C(=O)O)c2ccc(N3CCC(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CC4)CC3)cc21 +NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1cccnc1-n1ccc(C2CC2)n1 +CCCC1Oc2ccc(-c3cncnc3)cc2C2(COC(N)=N2)C12COC2 +O=C(Nc1ccc(C(=O)N2CCN(c3cnccn3)CC2)cc1)N1Cc2ccc(C(F)(F)F)cc2C1 +CN1CCC(OC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +CCOC(=O)C1(c2ccccc2)N=C(c2ccc(OC)cc2)N(Cc2ccccc2)C1c1ccc(NCC2CCCCC2)cc1 +Cc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccccc2Cl)c(C)c1 +CC(C)CN1CCC(n2nnnc2CCCOc2ccc3[nH]c4nc(O)nc-4cc3c2)CC1 +CCCCN1CCN(c2nc3c(S(=O)(=O)c4cccc5ccccc45)cccc3o2)CC1 +CS(=O)(=O)N1CC=Cc2cccc(c2)Nc2ncc(C(F)(F)F)c(n2)NCc2cccnc21 +[C-]#[N+]C1(C)CCC2C(C)CC3C=C(C)C(C)C4CCC1C2C34 +COCOC(C)(C)c1ccc(-c2ccnc(NCc3ccc(C(=O)Nc4ccccc4N)cc3)n2)cn1 +Cc1cc(C)nc(-n2nc(C)cc2Nc2ccccc2)n1 +CN1CCC2(c3cccc(O)c3)CC(=O)C(=Cc3cccc(Cl)c3)C1C2 +CCCc1cc2c(OC)noc2c(CCC)c1OC(C)(C)C(=O)O +COc1cc2c(c3c1c(=O)c1cc4ccccc4cc1n3C)C(O)C(OC(=O)C=Cc1ccc(Br)cc1)C(C)(C)O2 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+CC(=O)Nc1nc2ccc(-c3nn(Cc4cc5cccc(F)c5c(=O)n4C(C)C)c4ncnc(N)c34)cc2s1 +CCCC(=O)NCc1nc(-c2ccc3[nH]c4c5c(c6c(c4c3c2)C(=O)NC6=O)CCC5)cs1 +Cn1c2ccc(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +COc1ccc(OC)c(-c2cccn(C(CN3CCC(O)C3)c3ccccc3)c2=O)c1 +Cc1ccc(OCc2nc(-c3ccccc3)no2)c(C)c1 +COc1cccc(-c2cccc(C3(C)N=C(N)CCS3)c2)c1 +COc1cc(N2CCN(S(C)(=O)=O)CC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +Cc1cc2ccccc2nc1-c1ccc(N(Cc2ccc(F)cc2)C(=O)c2ccc(O)cc2O)cc1 +CC(C)C(=O)N(c1ccc([N+](=O)[O-])cc1)C1CCC2C3CCC4N(C)C(=O)CCC4(C)C3CCC21C +N=C(N)Nc1ccc(NC(=O)c2cc3cc4ccccc4cc3c(Br)c2O)cn1 +COc1cc(-c2cn(CC(=O)N(Cc3ccccc3)C(C)c3ccccc3)nn2)ccc1-n1cnc(C)c1 +CC(=O)c1ccc(N2CCN(C(=O)c3cccc(Cl)c3)CC2)s1 +COc1cccc2c1CCN(Cc1ccc(C(C)NC(=O)c3cncs3)cc1)C2 +Cn1c(C#N)ccc1-c1ccc2c(c1)CCCC2(O)c1ccccc1 +Cc1c(COC(=O)NC(=N)N)cccc1-c1cnc(N2CCOCC2)nc1 +COc1cccc(-c2n[nH]c(Cc3ccc(Cl)c(Cl)c3)n2)c1OC +Cc1cc(C)c(S(=O)(=O)NC(=N)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)c(C)c1 +Oc1ccccc1CNCCCCCCCCCNc1c2c(nc3ccccc13)CCCC2 +Cc1ccccc1-c1cn(C2OCC(O)C2O)c2ncnc(Nc3ccc4c(c3)OCCO4)c12 +O=C(O)CC(NC(=O)CNC(=O)c1cc(O)cc(NC2=NCC(O)CN2)c1)c1cc(Cl)cc(I)c1O +CC(C)N1CCC(Oc2ccc3c(c2)CCN(C2CCN(C4CCC4)CC2)C3=O)CC1 +CCCCCCCCCNC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 +OC1CCN(CCOc2ccc(Oc3nc4ccccc4s3)cc2)CC1 +c1ccc2c(NCCCCCCN3CCCCC3)c3c(nc2c1)CCCC3 +C=CCCN1CCN(C(=O)c2ccc(NCc3ccc(-c4cccc(F)c4C(=O)OC)cc3F)nc2)CC1 +Cc1c(-c2ccnc(N)n2)sc2ccc(C(N)c3cccc(Cl)c3)cc12 +COc1cc(C=CC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1 +COc1ccc(-c2[nH]c(-c3ccccc3)nc2CCNS(=O)(=O)N2CCN(c3ccccc3)CC2)cc1 +COc1cccc(C2(N3CCN(c4ccccc4)CC3)C3CC(C)CC32)c1 +COc1ccc(Nc2ncc(C(N3CCN(S(C)(=O)=O)CC3)C(F)(F)F)cc2-c2nc(C)nc(N)n2)cn1 +Cc1cc(N2CCC(C)CC2)nc2ccc(NC(=O)C3CCC(C)CC3)cc12 +CS(=O)(=O)c1ccc(-c2ccc3c(-n4ccnc4)c(C#N)cnc3c2)cc1 +N#Cc1c(N)nc(SCc2csc(-c3ccc(Cl)cc3)n2)nc1-c1ccc(OC(F)(F)F)cc1 +CN(Cc1cccc2ccccc12)C(=O)C(O)C(N)CC1CCCCC1 +O=S(=O)(c1ccc(Cl)cc1)N1Cc2c[nH]nc2CC1c1ccccc1 +CCCC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(OC)c3)cc2c1Nc1ccc(N2CCNCC2)nc1 +O=C(O)c1ccc(N2C(=O)C3ON(c4ccccc4)C(c4ccc([N+](=O)[O-])cc4)C3C2=O)cc1 +Cc1nnc(C)n1-c1ccc(OCCCN2CCCCC2)cc1 +Cn1c(=O)cc2c3c(c(N)ccc31)C(=O)c1ccccc1-2 +CC(CO)n1c2cnccc2c2cnc(Nc3ccc(N4CCC(O)C4)nn3)nc21 +O=C(Cc1cccc(NCC(F)(F)c2ccccn2)[n+]1[O-])NCc1cc(Cl)ccc1-n1cnnn1 +CCC(NC(=O)C1CC(Sc2ccccc2)CN1C(C)=O)C(=O)c1nc2ccccc2o1 +CC(C)(O)COc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +COc1cc(Nc2nc(N)nc(-c3ccccc3)n2)ccc1-c1cnco1 +CCOc1cc(N2CCOCC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OCc2ccc(-c3ccccc3)cc2)C1c1cccc([N+](=O)[O-])c1 +COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(OC)cc2)cc1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1cc(Cl)ccc1-n1cnnn1 +CC(C)(C)NC(=O)Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +Cc1cc(C)cc(CC(=O)N(C)CC(c2cccc3c2OCO3)N2CCC(N3CCCCC3)CC2)c1 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ncc(F)cn2)CC1c1cccc(F)c1 +COc1cc(OCc2csc(CN(C)C)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Nc1ncc2c(n1)-c1ccccc1C(c1ccccc1)=NC2 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(C#N)c2NCc2cccs2)nc1 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+O=Cc1cccc(CN2C(=O)N(Cc3cccc(C=O)c3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)c1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(NCc3cc(-c4ccccc4)no3)n2)[nH]n1 +CCCN(CCC)c1cc(C)nc2c(-c3ncc(C)cc3NC)c(C)nn12 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(N(C)C)c3F)C2)cc1 +O=[N+]([O-])c1ccc2[nH]c3cnc([N+](=O)[O-])cc3c2c1 +Nc1cc(Oc2ccccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)ccn1 +CC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(Cl)c1 +Cc1cn2ccc(N3CCC(OC(=O)N4CCN(C(C)C)CC4)CC3)cc2n1 +O=C1c2ccccc2S(=O)(=O)N1CCCCN1CCC(c2ccccc2)C1 +CC1(C)CC2CC(C)(CN2C(=O)c2cc(Cl)c(-c3csc4ccccc34)cc2Cl)C1 +CCc1nnc2ccc(-c3n[nH]c4ccc(C(=O)NC5CCCN(Cc6c(F)cccc6OC)C5)cc34)cn12 +COc1cc(C=CC(=O)NCCCNc2c3c(nc4ccccc24)CCCC3)ccc1OCCCCO[N+](=O)[O-] +CN(C)C(=O)C1CCN(c2ccnc3c2c(C=C2Oc4cccc(O)c4C2=O)cn3C)CC1 +Clc1cccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)c1 +NC1CC(O)CN(c2ccncc2NC(=O)c2csc(-c3c(F)cccc3F)n2)C1 +O=C(O)CNC(=O)c1c(=O)oc(O)c2ccc(-c3ccc(OC(F)(F)F)cc3)cc12 +O=C1NCc2c1c1c(c3c2c2cc(CO)ccc2n3CCCO)Cc2ccccc2-1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)cc1 +COc1ccc(C2C(c3ccccc3)C(=S)N2c2cc(OC)c(OC)c(OC)c2)cc1 +COc1cc(OC)c(-c2cc3ccccc3o2)cc1C=CC(=O)c1ccc(C(=O)O)cc1 +CCCC1SC(=Cc2nc3ccc(F)cc3[nH]2)NC1=O +CC1=NNC(=O)CC1c1ccc(OC2CCN(C3CCC3)CC2)cc1 +Cc1ccc(C(=O)NC(=S)NNC(=O)COc2ccccc2C)cc1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OC3Cc4ccccc4C3)c(C(=O)O)c2)c1 +Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3Cl)ccc12 +Cc1ccoc1C(=O)Nc1cccc(Oc2ccnc3cc(C(=O)NCCO)sc23)c1 +COCc1nc2c(C(=O)NCc3ccccc3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +O=C(NNc1ncnc2sc3ccccc3c12)c1ccccn1 +CC(C)(CCO)NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CCCCn1c(Sc2cc(OC)c(OC)c(OC)c2Cl)nc2c(N)ncnc21 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCC23CCCC2(O)CCC3)cc1F +FC(F)(F)c1cc(CNCc2cnccc2-c2ccccc2)cc(C(F)(F)F)c1 +Cc1c[nH]c2cccc(OCC(O)CN3CCN(C(c4ccccc4)c4ccccc4)CC3)c12 +O=C(Cc1ccccc1)Nc1nnc(CCSCc2nnc(NC(=O)Cc3ccccn3)s2)s1 +CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(-c4ccncc4)c[nH]c3n2)c(OC)c1 +Cc1c(Br)cc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 +O=C(Cc1ccccc1)NC(Cc1ccc2ccccc2c1)NC(=O)C1CCCCC1NC(=O)c1c[nH]c2ccccc12 +Cc1cc(C)cc(NC(=O)Nc2ccc(NS(N)(=O)=O)cc2)c1 +CCCCC(C)C1CC(=O)NC(Cc2ccccc2)C(=O)NC(CO)C(=O)NC(Cc2ccccc2)C(=O)O1 +COc1ccc(-n2nnnc2N)cc1CNC1CCCNC1c1ccccc1 +O=C(C=Cc1ccc2c(c1)cc(C(=O)c1ccccc1)n2S(=O)(=O)c1ccccc1)NO +COc1cc2nc(N3CCN(C(=O)C4COc5ccccc5O4)C(C)C3)nc(N)c2cc1OC +COC(=O)C1CC(O)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +NS(=O)(=O)Oc1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 +Cc1ccc(N2CCc3ncnc(NC(CO)c4ccc(C(F)(F)F)nc4)c3C2)c(C#N)c1 +CC(C)(C)NC(=O)C1CCN(Cc2cc(NC(=O)c3cccc(C(F)(F)F)n3)ncn2)CC1 +COc1cc2ncnc(Oc3ccc(NC(=O)NC4(C#N)CCCC4)c4ccccc34)c2cc1OC +Cc1cccc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)c1 +CC(CC(=O)O)Cc1nc(CCCc2ccc3c(n2)NCCC3)no1 +CN1CCC(NC(=O)c2cc(-c3c(O)cc(O)cc3Oc3ccc(N4CCCC4)cc3)on2)CC1 +COc1cc(C2=NC(c3ccc(Cl)cc3F)C(C(=O)Nc3cc4cn[nH]c4cc3F)=C(C)N2)ccn1 +CCN(CCCCCCn1c(=O)c(=O)n(CCCCCCN(CC)Cc2ccccc2OC)c2ccccc21)Cc1ccccc1OC +COc1ccc(-c2cc(C(N)=O)nc3cc(C(O)Cc4ccc(Cl)nc4)ccc23)cc1 +Nc1cc(C(=O)N2CCCC2)cc2nc(-c3cccs3)nn12 +O=c1ccc2cc(N3CCN(CCCCc4c[nH]c5ccc(F)cc45)CC3)ccc2o1 +CCN(CC)c1nc2ccccc2n2nc(-c3ccco3)nc12 +CCCCN1CCC(COC(=O)c2ccc(N)c3c2OCCO3)CC1 +Cc1nnc2c(NC3CCN(S(=O)(=O)C4CCNCC4)CC3)cc(N(C)Cc3ccccc3)nn12 +CCN(CC)CCNC(=O)c1cccc2nc3ccc4c(OC)cccc4c3nc12 +CCc1ccc(C(=O)C[n+]2cc(-c3ccc(C)cc3)n3c2CCC3)cc1 +O=C(NCCCNCCNC(=O)OCc1ccccc1)OCc1ccccc1 +Cc1cc(Cl)ccc1NC(=S)NNC(=O)C(O)(c1ccccc1)c1ccccc1 +CCN(CC)C(CNC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO +C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCCn4ccnc4[N+](=O)[O-])cc23)c1 +Cc1ccc(C(=O)Nc2cccc(Br)c2)cc1C#Cc1cnc2ccnn2c1 +O=C(N1CCC(F)CC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +Cc1ccc2c(c1)c1c(n2CCc2ccncc2)CCN(C)C1 +CCOCCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N(Cc1ccccc1)C(C)c1nc(-c2ccccc2)c[nH]1 +CC1(C)OC(c2ccnc(NCCC#N)n2)=C(c2cc(Cl)cc(NS(=O)(=O)c3c(F)cccc3F)c2F)C1=O +CN1CCN(C)C(c2c(-c3ccccc3)[nH]c3ccccc23)C1 +Cc1nnc(NC(=O)CSc2ncnc3c2cnn3-c2ccccc2C)s1 +Cc1ccc2c(OCCN3CCC(Cc4cc5c(cc4F)OCC(=O)N5)CC3)cccc2n1 +CC(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2ncc[nH]2)c1 +O=S(=O)(c1ccccc1)C1CC2(c3ccccc3)NC1CCC2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1cc(C#N)cc(-c2ccc(C3CC3NC3CCC(N)CC3)cn2)c1 +O=C(CNc1ccccc1)NN=Cc1c(O)ccc2ccccc12 +Cc1[nH]c(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)Nc2ccccc2)nc1C(=O)O +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1Br +Cc1[nH]nc2c1C(c1cc(Br)cc(-c3ccc(Cl)s3)c1)(C(C)C)C(C#N)=C(N)O2 +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)c(Br)n2)c(F)c1 +Oc1ccc2c3c1OC1C(Nc4ccccc4)CCC4(O)C(C2)N(CC2CC2)CCC314 +CN(CC(CCN1CCC(n2ccnc2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +c1ccc(Nc2nc3c(N4CCCCC4)ncnc3s2)cc1 +NC(CNc1nc(-c2ccncc2)nc2c(Br)csc12)CC1CCCCC1 +NCCn1cc(S(=O)(=O)c2ccccc2)c2cccnc21 +NCCCNC(=O)c1ccc(NC(=O)CSC(=O)N2CCCc3cc(Cl)cc(Cl)c32)c(Cl)c1 +COc1ccc(-c2nnc(C(=O)C(NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)C(C)C)o2)cc1 +CCN(CC)c1nc(C)nc2c(-c3ccc(Cl)cc3Cl)c(C)nn12 +O=C(CN1CCN(c2ccc(Cl)cc2)CC1)NC1C2CC3CC(C2)CC1C3 +Cc1cccc(-c2c(C(=O)c3ccccc3)oc3ccc4c(C)cc(=O)oc4c23)c1 +O=C(NC1CCCC1NC(=O)c1ccc2c(Cl)c[nH]c2c1)c1ccc(N2CCOCC2=O)cc1 +COc1cc(C(=O)c2cc(Cl)ccc2N)cc(OC)c1OC +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)CCCN(C)C)ncn3)cccc2s1 +CC(=O)OC1(c2ccccc2)CCN2CC(c3ccccc3Cl)CCC2C1 +COc1ccc(-n2cnc3ccc(-c4nnc(SCc5ccc(OC)c(C(F)(F)F)c5)o4)cc32)cc1 +O=C1c2ccc(Nc3ccc(F)cc3F)cc2CCc2ccc(OCCCO)cc21 +CN(C)CCNC(=O)c1ccc(C=NNc2ncnc3c2cnn3-c2cccc3[nH]cnc23)cc1 +Cc1nn(-c2ccccc2)c(C)c1C=NN1CCN(Cc2ccccc2)CC1 +Cn1cc(-c2ccc3nnc(Cc4cccc5c(=O)[nH]ccc45)n3n2)cn1 +CC1CN(Cc2c[nH]nc2-c2cc(C#N)c[nH]2)CCN1c1ccc(C(F)(F)F)cn1 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCC2)CCN(C2CCCCC2)C1 +COC1C(F)CN(C(=O)Cn2cc(C(C)=O)c3ccccc32)C1C(=O)NC1(c2ccc(Cl)cc2)CC1 +CC(C)(C)c1cccc(C=CC(=O)Nc2ccc3c(c2)OCCO3)c1 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCC(F)(F)C2)c(-c2cncnc2)c1 +N#Cc1cccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3ccc(CCN4CCOCC4)cc3)c2)c1 +COc1ccccc1-c1csc2nc(N3CCNC(C(N)=O)C3)nc(N3C4CCC3COC4)c12 +COc1ccc(-c2ccc3c(n2)N(C2=NC(=O)C(C)(C)S2)CCO3)cc1OC +Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OCCF)c(C3CC3)cn2)no1 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+CN(CC=Cc1ccc(-c2ccccc2)cc1)Cc1ccc2c(c1)OCCC2 +CN(Cc1ncc2ccccc2c1CNC(=N)N)C1CCCc2cccnc21 +O=[N+]([O-])c1ccc2c(c1)[nH]c1c3ccccc3nc3cccc2c31 +CN(C)CCOc1cc(-c2cn[nH]c2)ccc1NC(=O)C(N)c1ccc(Cl)cc1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1[N+](=O)[O-] +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)COc2ccc(C(C)(C)O)cc2)CC(O)CC1O +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)C(F)(F)F)CC2 +NC(=O)c1ccc(NC2CCCCC2N)cc1Nc1cccc(-c2ccccc2)n1 +Nc1ccc(-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)nc1 +CC1(COc2ccc3c(c2)C2(COC(N)=N2)c2cc(-c4cccnc4)cc(F)c2O3)COC1 +Cc1cc(C)c(NC(=O)N(Cc2ccc(-n3nccn3)cc2)C2CCCCCC2)c(C)c1 +COc1ncc(Nc2ncccc2-c2nc(C)nc3[nH]cnc23)cn1 +COC(=O)C1(c2cccc(OCC3CCCCC3)c2)CC1C(=O)NO +CN(C)CCNC(=O)c1cccc2cc3c(nc12)-c1ccccc1S3(=O)=O +CC(NC(=O)C1(N)CCN(c2ncnc(N)c2-c2cn[nH]c2)CC1)c1ccc(Cl)cc1 +COc1ccc(C(C#N)(CCCNCCc2ccc(O)c(I)c2)C(C)C)cc1OC +CNC(=O)C=C1COc2cc(OS(=O)(=O)CCC(F)(F)F)ccc21 +CC1(C)OC(S)=Nc2ccc(-c3ccc(C#N)s3)cc21 +Clc1ccc2oc(NC(CN3CCSCC3)c3ccccc3)nc2c1 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+Cc1ccc(F)cc1Nc1nc2ccc(CC(=O)N3C(COC4CCC(C(=O)O)CC4)CCC3CN(C)C)c(F)c2o1 +O=C(O)c1n[nH]c2cc(Cl)c(-c3ccc(C4CCOCC4)cc3)cc12 +CCC(NC(=O)c1cc(C(=O)NC(C)c2cnccn2)n2c1COCC2)c1ccccc1 +Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c(=O)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 +CC(C)(C)CN(C(=O)CCC(=O)N1CCN(S(C)(=O)=O)CC1)c1ccc(Cl)cc1C(O)c1ccccc1Cl +CCC1CN(c2ncc(C(=O)NC)nc2C)CCN1C1CCN(C(=O)c2ccc(Cl)nc2N)CC1 +CNc1nccc(-c2ccc(C(=O)NC(CO)Cc3ccc(Cl)cc3Cl)s2)n1 +Cc1nc2ccccc2nc1N1CCc2ncnc(Nc3ccc(C(C)(C)C)cc3)c2CC1 +CC1(c2nnc(-c3nn(-c4ccc(Cl)cc4Cl)c(-c4ccc(Br)cc4)c3Cn3cncn3)s2)CC1 +Cc1cc(OCC(C)C)ccc1C(C)Nc1nccc(N2C(=O)OCC2C(C)C)n1 +O=C(c1ccc(F)cc1)C1CCN(CC2CC3c4ccccc4Cc4ccccc4C3O2)CC1 +Cc1cc(N)nc(C)c1CNC(=O)c1ccn(S(=O)(=O)c2ccc3c(ccn3C)c2)c1 +Nc1cc(N)c2cc(CCc3ccc(C(=O)NC(CCCNC(=O)c4ccccc4C(=O)O)C(=O)O)cc3)ccc2c1 +Cc1ccc(N2CCN(CCC3CCC(NC(=O)C4CCCCC4)CC3)CC2)cc1C +Cc1ccccc1C#Cc1ccc2c(n1)CCN(C1CCCC1)C2=O +CC(=O)NC1C(N)C=C(C(=O)O)OC1C(=O)N(CCc1ccccc1)C(C)C +CC(C)Oc1ccc(-c2nnc(-n3cc4c(n3)CCN(CCCC(=O)O)C4)s2)cc1C#N 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+CC(NC(=O)c1cc(F)cc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(C(=O)O)cc1 +O=C1C2C3C=CC(C4C=CC43)C2C(=O)N1CCCCN1CCN(c2cccc(Cl)c2)CC1 +N#CC(=Cc1ccc(Sc2ccccc2)o1)c1nc2ccccc2[nH]1 +CCc1cc(O)c(OC)c(C(=O)NCC2CCCN2CC)c1OC +Cc1ccc2oc(=O)c(C=Nc3ccc(S(=O)(=O)NC(=N)N)cc3)c(Cl)c2c1 +NC1CCN(c2ccc(N3Cc4cn(-c5ccc(Cl)cc5)nc4C3=O)cn2)C1 +Cc1cc(F)ccc1C1CN(C(N)=O)CCC1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC1CN(C(=O)OC2CCOC2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Cc1nn(C)cc1-c1nc2c(Oc3ccc(C(=O)NC4CCC4)cc3)c(Cl)cnc2[nH]1 +CCC(CC)NC(=O)C(NC(C)=O)C1CC(C(=O)O)CC1N=C(N)N +CC(O)(c1cncc(N2CCC3(CCOC3)CC2)c1)C(F)(F)F +COc1ccccc1CN=C(N)c1cc2cc(Cl)ccc2[nH]1 +CC1=Nc2cc(=O)n(S(=O)(=O)c3ccccc3)n2C(c2cccc([N+](=O)[O-])c2)C1=C(O)OC(C)C +CN1CC(Cc2ccccc2)(c2ccc(F)c(OCCNS(=O)(=O)c3cn(C)cn3)c2)C1 +FC1(F)CCN(c2cc(-c3n[nH]c4ccc(-c5cccnc5)cc34)ncn2)CC1 +O=C(Nc1ccccc1-c1nc2c(C(=O)O)cccc2o1)c1ccccc1 +CNc1cc(NC(=O)OC)ccc1Nc1c2ccc(Br)cc2nc2c(OC)cccc12 +O=C(O)CCCC(=O)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 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+CCC(=O)c1ccc(F)c(C2CC2NC(=O)Nc2ccc(Br)cn2)c1O +CCC1CCCC(C2(CC(=O)N3CCC(N4CCCCC4)CC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +COc1ccn2c(c1)nc1c2c(=O)n(CCC(C)C)c(=O)n1Cc1ccccc1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(C(=O)CCN)CC2)CC1 +Cc1ccc2c(c1)Oc1sc(Cl)cc1C(N1CCN(CC(C)(C)C(=O)O)CC1)=N2 +Nc1nc(N)c2ncn(CC3COP(=O)(OCC(F)(F)F)CO3)c2n1 +COc1ccc(Cl)c(-c2noc(C(C)C)c2COc2ccc(-c3ccc4c(C(=O)O)cn(C)c4c3)c(C)c2)n1 +CNc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cn1 +CCCCCCCCCCCC(=O)NC1CCc2cc(OC)c(OC)c(OC)c2-c2ccc(OC)c(=O)cc21 +C=C1COC2(CN(c3ncc(C(=O)O)s3)CCC2NC(=O)c2[nH]c(C)c(Cl)c2Cl)OC1 +CCNc1cc(C(=O)NC(Cc2ccccc2)C(O)CNCc2ccccc2)cc(N2CCCCS2(=O)=O)c1 +O=C1NC(=O)c2c1c1c3ccccc3ccc1c1[nH]c3ccccc3c21 +Cc1nc(C)c(CNc2nc(OCC#Cc3ccccn3)nc(Cl)c2C)s1 +COc1ccc(Oc2ccc(NC(=O)NC(Cc3ccccc3)C(=O)NCCCN3CCOCC3)cc2)cc1 +Cc1c(-c2cccc(O)c2)[nH]c2ccc(N3CCCCC3)cc2c1=O +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccnc2)n1 +CCCCCCc1nc2cc(C=CC(=O)NO)ccn2c1NCCC(=O)NC(C)(C)C +CC(=C[S+](C)[O-])n1c(C(=O)c2ccc(Cl)cc2)noc1=O +Cc1c(N(Cc2ccc(C(F)(F)F)cn2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +COc1ccc(N2N=C(S(C)(=O)=O)C3CCN(c4ccc(C5(CN6CCCC6)CC5)cc4)C(=O)C32)cc1 +N#CC1(NC(=O)C2CCCCC2C(=O)N2CCN(c3nc4ncccc4s3)CC2)CC1 +CCCc1ccc2c(c1)sc(=O)n2CCCCN1CCCCC1 +O=C1C2C3C=CC(C3)C2C(=O)N1c1ccc([N+](=O)[O-])c2ccccc12 +O=C(NC(C(=O)N1CCCC1B(O)O)c1ccccc1)c1ccnc2ccccc12 +COc1cccc2c(-c3ccc(O)c4c3CCNC4)ccc(O)c12 +CCN(C(=O)C(C)(C)C1(O)CCN(CCc2ccccc2Cl)CC1)c1ccccc1OC +CCNC(=O)C(=O)C(Cc1ccc(C)cc1)NC(=O)C(NC(=O)CCCCC1CCSS1)C(C)C +Cc1ccc(NC(=O)c2[nH]c(C3(C)CCCCC3)nc2CCC23CC4CC(CC(C4)C2)C3)cc1C(=O)O +Cc1ccc2c(c1)-c1nnc(-c3ccc(C4(N)CCC4)cc3)n1-c1cccnc1N2 +Oc1ccc(C(=C2CCCCCC2)c2ccc(O)cc2)cc1 +C=CCN(c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CCOC(=O)c1cnc(NCc2ccc(OC)cc2)n2nc(-c3ccco3)nc12 +Cc1cc2c(cc1C)-n1cnnc1CC(c1ccc(-n3c(C)nc4cnccc43)cc1)=N2 +CCN(CCCCCCNC1=CC(=O)C(NCCCCCCN(CC)Cc2ccccc2Cl)=CC1=O)Cc1ccccc1Cl +COc1ccc(-c2cc(NC(=O)C3Cc4ccc5ccccc5c4C3)[nH]n2)cc1OC +COc1c(OCC2CC2)ncnc1N1CCC(Oc2ccc(C(C)NC(=O)c3cnco3)cc2)C1 +O=C(Cn1cnc2cccnc21)N1CCN(c2sc(C(F)(F)F)nc2-c2nc3ccccc3[nH]2)CC1 +O=S(=O)(Nc1ccc(Cl)cc1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +CC(=O)c1nn(CC(=O)N2C(C(=O)NC3(C4CCCCC4)CC3)CC3CC32)c2cnccc12 +COc1ccc(C(=O)N2c3ccccc3Oc3cc(C#N)ccc32)cc1 +CC(=O)N1CCC(c2ccc(N3CCOc4ncnc(N)c4C3=O)cc2)CC1 +CS(=O)(=O)N1Cc2cc(Br)ccc2N(Cc2c[nH]cn2)CC1Cc1ccccc1Cl +Nc1ccccc1NC(=O)c1ccc(CN(CCO)Cc2ccc(-c3cccs3)cc2)cc1 +CN(c1cc(CO)ccc1Cl)c1nc(Nc2cc(N3CCOCC3)cc(S(C)(=O)=O)c2)ncc1F +Cc1cc(Nc2nn(Cc3ccc(F)cc3)c(=O)c3ccccc23)n[nH]1 +CCN(CC=CC#CC(C)(C)C)c1cccc2c1CCC(=O)N2 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCc1ccc([N+](=O)[O-])cc1 +Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(NCC6CC6)c5)cc(C(F)(F)F)nc34)cn2)cn1 +COCOc1c(Br)ccc2oc(-c3cn4nc(OC)sc4n3)cc12 +COc1ccc2cnc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)nc2c1C(C)C +Cc1cc(C(C(=O)NC(C)C)N2C(=O)C(C3Cc4ccccc4C3)NC(=O)C2CC(C)C)oc1C +OCC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 +CSCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O +Cc1cc(C)cc(-c2cnc(-c3cccnc3)c(C(=O)N(C)Cc3ccc4c(c3)OCO4)c2)c1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)Oc1ccc2c(c1)[nH]c1ccccc12 +COc1c(Cl)cc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)cc1Cn1ccnn1 +CCn1cc(C(=O)N2CCC(c3cccc(CN)c3)CC2)c2cccc(C)c21 +COCCc1sc[n+](CCCCCCCC[n+]2csc(CCOC)c2C)c1C +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(N(C)c3ccncc3)cc2)cc1 +c1ccc2c(NCCCCCCCCNCc3ccncc3)c3c(nc2c1)CCCC3 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3ccc4[nH]cc(CC(F)(F)F)c4c3)C2O)c1 +O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1cc(Cl)ccc12 +COc1ccc(C23CC2CN(CCCSc2nnc(-c4ocnc4C)n2C)C3)cc1 +CCC(C)(C)NC(C)C(O)c1ccc(C(F)(F)F)cc1 +COc1ccc(CNCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(=O)NC(C)(C)C)c(C)c1 +CN(C)Cc1ccc2c(c1)CCC(N(C)C(=O)c1ccc(-c3cccnc3)cc1)C2 +CCCC(CCC)c1ccc(Cl)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12 +Cn1cc(S(=O)(=O)N2CCC(CNC(=O)c3ccc(Cl)cc3Cl)(CC3CC3)CC2)nn1 +O=C(Cn1cnc2cc([N+](=O)[O-])ccc2c1=O)NC(=O)NCc1ccccc1 +O=C(O)CNc1cc(-c2cccc(NCc3cccc(F)c3)n2)c(Cl)cn1 +CC(=O)N1CCN(C(=O)c2cc(Sc3cnc(Nc4cccc(Br)n4)s3)ccc2O)CC1 +OC(Cc1ccc(F)cc1)C1CCN(CCCc2ccccc2)CC1 +CCC12CC(C)(O)C(O)(c3nccs3)CC1CCc1cc(O)ccc12 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc4c(-c5ccncc5)n[nH]c4c3)NC(=O)NC1=O)C2 +NC(=S)Nc1cccc(OCCCCCCCCNC(=S)Nc2ccc(Br)cc2)c1 +NC(=O)c1ccc2c(c1)nc(-c1ccccn1)n2C1CCCC(NC(=O)c2ccc(Br)s2)C1 +COc1cc(C(=N)N)cc2cc(CCCCCc3cc4cc(C(=N)N)cc(OC)c4o3)oc12 +CC(C)C1CCC2(CO2)C2C(=O)OCC(C(=O)OCc3ccc(-c4ccccc4)o3)=CC12 +CCCSCC1OC(n2cnc3c(NC4CCCC4)ncnc32)C(O)C1O +CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4c(c3)[nH]c3ccccc34)n2)c(=O)c1=O +CC(=O)N1CCCC1c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1 +COc1ccc(-c2snnc2-c2cc(OC)c(OC)c(OC)c2)cc1O +COc1cccc(-c2ccc(CC(CC(=O)NO)C(=O)NC3c4ccccc4CC3O)cc2)c1 +COc1nc(NCCCN2CCOCC2)nc(OC)c1NC(=O)c1ccc(Oc2cc3c(cc2C)CCC3(C)C)o1 +CNc1nc2cc(-c3cccc(C(=O)O)c3)sc2n2c(C)cnc12 +O=C(c1ccc(-c2ccccc2Cl)cc1)N(CC1CC1)CC1CCCO1 +O=C(c1ccccc1-c1ccccc1)N1CC(CN2CCC(c3ccccc3)CC2)C(c2ccccc2)C1 +O=C(Nc1nn[nH]n1)c1ccc(Cn2nc(-c3cc(Cl)cc(Cl)c3)cc2-c2ccc(OC(F)(F)F)cc2)cc1 +CCCCn1c(=O)[nH]c(=O)c2c(C(=O)OCC)cc(-c3cccs3)nc21 +O=CC(Cc1ccccc1)NC(=O)c1ccccc1C#Cc1ccccc1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCC3=CC(=O)CCC3(Cc3ccccc3)C2)cc1 +COc1cc2c(NC3CCN(C(C)C)CC3)nc(N3CCCN(Cc4ccccc4)CC3)nc2cc1OCCCN1CCCC1 +O=S(=O)(NCc1cnccc1-c1c(F)cccc1F)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(C)(C(=O)NC(N)=O)C1c2ccc(-c3ccc(C(=O)N4CCC(F)C4)cc3)nc2Oc2c(F)cccc21 +Cc1nc(N(C)c2ccc(N=[N+]=[N-])cc2)c2ccccc2n1 +Nc1nc(O)c2ncn(COCCCCP(=O)(O)O)c2n1 +CNCC(CC1CCCCC1)NC(=O)N1CCCC(C(OCCCOC)c2cccc(Cl)c2F)C1 +CCN1CCCC12CCN(C(=O)c1cc(Cc3n[nH]c(=O)c(C)c3C)ccc1F)CC2 +O=C(O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2Oc2ccc(OC(F)(F)F)cc2)cn1 +Fc1cc(Cl)ccc1C(NC1CCN(c2c(F)cccc2F)CC1)c1cccnc1 +COc1ccc2nc(C)c3c(C)nc(-c4c(C)n[nH]c4C)n3c2n1 +NC1=NCCCCN1Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 +Cc1ccc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(N)c34)cc2)cc1 +O=S(=O)(NCC(c1cccnc1)N1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 +CN(C)C(=O)c1c(CNC(=O)c2cnn(C)c2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +CCCCCCC=C1CC(CO)(COC(=O)c2ccc(C(F)(F)F)cc2)OC1=O +[O-][S+]1CC(O)C(O)C(O)CC(O)CC(O)C(O)C(O)C(O)C1 +CCc1cc(CC)n2nc(-c3ccc(OC)cc3)c(CC(=O)N(CC)CC)c2n1 +NS(=O)(=O)c1ccc(N=c2scc(-c3ccc(Br)cc3)n2C2CCCCC2)cc1 +O=c1c2c(O)cc(O)cc2ncn1-c1ccc(O)cn1 +COC(=O)c1c(F)cccc1-c1ccc(CNc2ccc(C(=O)N3CCN(C(=O)C(C)(C)C)CC3)cn2)c(F)c1 +CCNC(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)c3ccccc3-c3cccnc3)cc2F)CC1 +CCc1[nH]c2nc(Sc3ccc4c(c3)C(=O)NC4)nc(N3CC4C(N)C4C3)c2c1Cl +O=C(Nc1cc(-c2ccc(O)cc2)cn(CC(F)(F)F)c1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1 +CC1CN(Cc2ccc3c(-c4cnn(C)c4)cc(C(N)=O)nc3c2)CCO1 +Nc1nccnc1-c1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 +CC(C)COC(=O)N1CCC(C#N)C(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)C1 +CN(c1cncnc1)c1cc(C(=O)Nc2cccc(Cl)n2)ccc1F +CN1CCN(CCCNc2nccc(-c3c(-c4ccc(C(F)(F)F)cc4)nn4cc(C(F)(F)F)ccc34)n2)CC1 +CC(=O)SCC(C)C(=O)N(CC(=O)O)c1ccc(C(C)C)cc1 +CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCCNc1ccnc2cc(Cl)ccc12 +Cc1cc(=O)[nH]c(C)c1C(=O)N1CC2CN(CCC(NC(=O)C3CCCC3)c3ccccc3)CC2C1 +O=C1C(=O)N(Cc2cc3ccccc3s2)c2ccc(I)cc21 +CN(c1ncnc2[nH]ccc12)C1CC(CS(=O)(=O)N2CCCC2)C1 +N=C(N)NCCCC(NC(=O)c1ccccc1-c1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O +COc1ccc(NCCNC(=O)C(CC2CCCCC2)NC(=O)c2cccc(C)c2)cc1 +COc1ccccc1NC(=O)Cn1cnc2sc(C(=O)Nc3ccc(F)cc3)c(C)c2c1=O +CCOc1ccccc1-c1cccn2nc(Nc3ccc4c(c3)CCN(CCS(C)(=O)=O)CC4)nc12 +Cc1ccc2ccc(N3CCC(Oc4nccnc4C4CCOCC4)CC3)nc2c1 +Cn1cc(-c2cnc(N)c(-c3ccc(C(=O)NC4CC4c4ccccc4)c(F)c3)n2)cn1 +Cc1c(CN2CCN(c3ccccc3)CC2)cnn1-c1ccccc1 +O=C(Nc1ncc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cn1)c1ccccc1 +Cc1c(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cnn1-c1ccccc1 +NC(CC(O)c1cc2ccccc2c2ccccc12)=NN=Cc1ccccc1 +Cc1c(CNc2ccc(C(=O)NC(CC(=O)O)C(=O)O)cc2)ccc2ncnc(N)c12 +c1ccc(-c2ccc3c(c2)OC(C2=NCCN2)CO3)cc1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4cccnn4)nc31)C(O)C2O +CCOc1cc(CN2CCC(NC(=O)c3ccc(NC)nc3)CC2)cc(OCC)c1-c1ccc(F)cc1 +COC1CCC2(CC1)Cc1ccc(C#CC3CC3)cc1C21N=C(N)N(Cc2nnc(C)s2)C1=O +CC(=O)OCc1cc(-c2ccc(S(C)(=O)=O)cc2)n(-c2ccc(F)cc2)c1C +NC(CNC(=O)c1cc(Br)c(-c2ccnc3[nH]ccc23)s1)c1ccccc1 +CC(C)CNC(=O)c1ccc2c(c1)N=C(c1ccc(Cl)s1)c1ccccc1S2 +COc1ccc2cc3[n+](cc2c1OCCCOc1ccc(-c2cc4ccccc4o2)cc1)CCc1cc2c(cc1-3)OCO2 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+CC(=O)N1CCC(c2nc(C)c(-c3cc(C(=O)N4CC(c5ccc(C#N)cc5)C4)ccc3C)[nH]2)CC1 +CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)N=c1sc(C(C)(C)C)nn1CC1CCC1 +Cn1cc(-c2ccc(-c3cncc(F)c3N3CCC4(CC3)CNC(=O)O4)cc2)cn1 +CC(Cc1ccc(O)cc1)NCC(O)COc1ccc(O)cc1 +Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4ccnc(C(F)(F)F)c4)c(Cl)c3)c21 +Cc1cc(COc2ccc(C(=O)NC3CN(C(C)(C)C)CCC3C(=O)NO)cc2)c2ccccc2n1 +Cc1ccccc1Oc1nc(Nc2ccc(C#N)cc2)nc2ccccc12 +CCC(CN1CCOC(C)(C)C1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCN(C)C)c1ccccc1 +COc1ccc(C)n2nc(CCc3cn(C)c(-c4cccs4)n3)nc12 +Nc1ccccc1NC(=O)c1ccc(CNCc2nc(-c3ccc(F)cc3)no2)cc1 +Nc1ccccc1NC(=O)c1ccc(CNc2cc(-c3ccccc3)[nH]n2)cc1 +COc1cccc(CNC(=O)c2cc(-c3nnn(Cc4ccc(C(=O)O)cc4)n3)ccn2)c1 +CC(C)(O)c1nc2cc(Cl)ccc2n1C1CCC(NCC2Cc3ccc(C(F)(F)F)cc3C2)CC1 +CCCCC(CC(CCc1ccc(Cc2ccccc2)cc1)C(=O)NC(C(=O)Nc1ccccc1)C(C)(C)C)C(=O)O +C#CCn1cc(-c2cnc(N)c3c(-c4ccc(Oc5ccccc5)cc4)csc23)cn1 +Cc1coc(-c2cccc3c2CCN2C(=O)CN=C(n4cnc(C5CC5)c4)C=C32)n1 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+O=C(Cn1c(-c2ccccc2)nc2ccc(-c3cccc(CN4CCCC4)c3)cc2c1=O)NCC1CC1 +Cc1c(C)c2ccc(OCC=Cc3ccccc3)cc2oc1=O +C=CC(=O)Oc1ccccc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2OC)ncc1Cl +Cn1c(=O)cc(NC2CCN(Cc3ccc4c(c3)OCO4)CC2)c2cc(OC(F)F)ccc21 +Cc1cc(C2=CCN(S(=O)(=O)CC(=O)NO)CC2)ccc1-c1ccccc1 +Nc1cccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)c1 +CCCC(Oc1ccc(-n2cc3cccc(Cl)c3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 +Cc1nnc(Nc2cc(C(=O)NC3CC3)ccc2Cl)c2cnn(-c3c(F)cccc3F)c12 +O=C(c1ccc(F)cc1)N1CCN2C(=O)c3ccccc3C12c1cccc(Cl)c1 +Cc1ccc(C2CC2COc2nc(C)ncc2-c2ccc(=O)n(C(C)C)c2C)nc1 +COCCN1Cc2cccc(C(=O)Nc3cccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)c3)c2C1=O +CCc1ccc(-c2ccc(CN3CC(C(=O)O)C3)cc2)cc1 +CS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2ccccc2Cl)cc1 +C=C(C)n1c(=O)n(CCN2CCC(N(C(=O)CC)c3cc(Cl)ccc3Cl)CC2)c2ccccc21 +COc1cc(-c2cc(OC(C)C3CNC(=O)C3)c3cccnc3c2)ccc1C(F)(F)F +O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1ccc(Nc2cc(N3CCC3)ncn2)cc1 +CC(C=CC1CC1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=CC(=O)O +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(OCC(=O)N(C)C)ccc3N2)c(O)c2cccnc21 +O=C(Nc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1)c1ccc(Cl)cc1 +Cc1sc2nc(NC(=O)CCCc3ccccc3)sc(=O)c2c1C +CC12COS(=O)OC1CCC1(C)C2CCC2CC3CC21CCC3(O)CO +O=C(Nc1ccc(Cn2cncn2)cc1)c1ccccc1NCc1ccncc1 +CCOc1ccccc1CN1CCN(Cc2[nH]c3ccccc3c2C)CC1CCO +Cc1ccc(C)c(Cn2cc(CCNc3ncnc4c3ncn4C3OC(C(=O)NC4CC4)C(O)C3O)c3ccccc32)c1 +O=C1NC(=O)c2c1c(-c1c(Cl)cccc1Cl)cc1c2c2cc(O)ccc2n1CCCC(=O)N1CCOCC1 +CC(C(=O)OC1CN2CCC1CC2)(c1ccccc1)c1ccccc1 +COCC(O)Cn1c(=O)cnn(-c2ccc(Cl)c(C(=O)NCC3(O)CCCCCC3)c2)c1=O +O=C(NO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1ccc(I)cc1 +COc1ccc(C2CC(=O)N(Cc3ccc(-c4ccno4)cc3)C2)c2c1oc1ccccc12 +CC1CN(CC(Cc2ccccc2)C(=O)NC(Cc2ccc3ccccc3c2)C(=O)O)CCC1(C)c1cccc(O)c1 +C=CCN1CC2C(Oc3ccccc3)CCC1CN2Cc1ccc(OC)cc1OC +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4ccc(C(F)(F)F)cc4)cc3)nc2c1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(C3CCC(F)C3)n2)cc1OC(F)F +Cn1cc(-c2cnc(N)c(-c3ccc(C(=O)NCc4ccsc4)c(F)c3)c2)cn1 +CCON=C(CCN1CCN(c2cccc(OCC)c2)CC1)c1ccccc1 +COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O +CCSC(=O)N1CCC(Oc2ncnc3c2CCN3c2ccc(S(C)(=O)=O)cc2F)CC1 +CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(F)cc2Cl)CC1 +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)Nc3ccccc3C(=O)O)cc12 +Cc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(N)c3ccccc3)c2=O)c1F +COC1CC2CCC(C1)N2c1nc(-c2cccc3[nH]cc(C)c23)nc2c1CN(c1cc(C(C)C)ccc1C)CC2 +CC(C)N(CC(O)COc1ccc(C(=O)c2ccccc2)cc1)C(C)C +O=C1OCc2cc(CCN3CCN(C(=O)Cc4ccc(-n5cnnn5)cc4)CC3)cc(Cl)c21 +OC1CCCN(c2ccncc2Nc2ncc3ccc(-c4ccccc4Cl)nn23)C1 +CCOC(=O)c1nn(-c2ccccc2)c(=O)c2c(N)scc12 +CC1c2ncn(-c3cnccn3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl +CCCCn1cc2c(nc(NC(=O)Nc3ccc(C(F)(F)F)cc3)n3nc(-c4ccco4)nc23)n1 +Cc1c(N(CCC2CC2)S(=O)(=O)c2ccc(C3=NOS(=O)N3)cc2)sc2ccccc12 +CC(C)NCCOc1cccc2c1ccn2S(=O)(=O)c1ccccc1 +COCCC(C)(C)NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1 +Fc1ccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)nc1 +O=C(O)CC1CCC2(CCN(c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)CC2)O1 +CN(C)CCNC(=O)c1cc2c3ccccc3n(C)c2c2cccnc12 +C#Cc1cc(Nc2ncnc3cc(O)c(OCCCCCCC(=O)NO)cc23)ccc1O +O=C(O)CC(=O)N1CCCN(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +CCCCc1ccc(C(=O)c2cn(CCC)c3ccccc23)c2ccccc12 +CCCc1nc2c(C)cc(C)nc2n1Cc1ccc2c(-c3nnn[nH]3)cc3ccccc3c(=O)c2c1 +N#Cc1ccc(CSc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 +CCCCNC(=O)N1CCC(c2cc(C)nn2-c2ccc(S(C)(=O)=O)cc2)CC1 +CN1CCCn2nc(C(=O)NCc3ccc(F)cc3)c(O)c2C1=O +CC#Cc1cncc(-c2cc3c(cc2C)CC2(CCC(OC)CC2)C32N=C(C)C(N)=N2)c1 +CC1CN(c2nnc(Cc3ccccc3)c3ccccc23)CCN1c1ccc(C#N)cn1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC4(C)CC4)c3)C2)cc1 +[C-]#[N+]c1ccc(N2C(=O)C3(CCC3)N(c3ccc(O)cc3)C2=S)cc1C(F)(F)F +Cn1c(CO)cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21 +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(Cl)c3)n3c2CCOC(C)C3)ccn1 +CCCC1(CCc2ccc(F)cc2)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)=C(O)O1 +CCc1cc2c(cc1Cn1c(C(=O)O)c(Cc3cccc(C(=O)O)c3)c(=O)c3cc(OCCCO)ccc31)OCO2 +COc1ccc2c(c1)C1OC1Cc1cc(OC)c(OC)c(OC)c1-2 +CNCC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2C(=O)CC(C)C)CC1 +O=C(CN1CCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 +COc1ccc(CCN2CCN(CCc3ccc(OC)cc3)CC2)cc1 +Nc1nc(NCC2CCC3CN(c4ncccn4)CCN3C2)nc2nc(-c3ccco3)nn12 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(-n5ccnc5)cc4F)nc23)N1 +CC1CN(Cc2ccc(N(C)C(=O)c3ccc(-c4cccc(C#N)c4)cn3)cc2)CCN1 +C=C(COCC(C)C1CCC2C(=CC=C3CC(O)CC(O)C3=C)CCCC21C)C1=CCCCC1(C)C +N#Cc1ccc(OCc2ccsc2)cc1OC(C(=O)O)c1cccc(Cl)c1 +CC(C)C1CCC(N2CCC(N3c4ccccc4CN(CC(=O)OC(C)(C)C)S3(=O)=O)CC2)CC1 +Oc1ccc(-c2csc(-c3ccc(O)cc3Cl)c2)c(Cl)c1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(Cl)s3)CC2)nc1 +COCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3c(F)ccc(F)c3Cl)cc2[nH]1 +COc1ccc2ncc(C#N)c(CC(O)C34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +O=C(Nc1ccc(-n2cnc3ccccc32)cc1)Nc1cccc(C(F)(F)F)c1 +CCOC1N(C2CC(N=[N+]=[N-])C(CO)O2)C(=O)NC(=O)C1(C)Br +CCOc1ccc(-n2nnc3cc(NCc4ccc(CC)cc4)ccc32)cc1 +O=C(O)c1cccc2c(=O)cc(-c3ccc(OCc4ccc5ccccc5n4)cc3)oc12 +COc1cc(C(=O)c2ccc(OC(C)C)c(N)c2)cc(OC)c1OC +CCOC(=O)c1[nH]c(C)c2cnnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12 +CCc1nn(C)c2c1CN(c1ncnn3c(C)nc(C4CCOCC4)c13)CC2 +CCNC(=O)Cn1c(-c2cccc(Cl)c2)nc2ccc(OCCCN3CCCCC3)cc2c1=O +CC(C)(C)OC(=O)N1CCC(NC(=O)c2nc3c(C(N)=O)cccc3[nH]2)CC1 +CN1CCC(OC(=O)C(C)(c2ccccc2)c2ccccc2)C1 +CC1NC(c2c[nH]c(=O)c(C(F)(F)F)c2)=NC1(c1ccc(F)cc1)c1ccc(F)nc1 +NC(=O)c1c(-c2ccc(NC(=O)Nc3ccccc3)cc2)nsc1NC(=O)NCCCN1CCOCC1 +Cn1ncnc1-c1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1 +COC(=O)n1c(=O)n(-c2ccc(C#N)cc2F)c2c3cc(OCc4ccccc4)c(OC)cc3ncc21 +COCCN1CCN(c2cc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)ccn2)CC1 +CCc1nc(-c2ncn3c2CN=C(c2ccccc2)c2cc(Cl)ccc2-3)no1 +COC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)ccc21 +CCOC(=O)CCN1CCN(CCOC(c2ccccc2)c2ccccc2Cl)CC1 +CC1CCN(C(=O)C(C)NC(=O)c2c[nH]c3ncc(C4CC4)nc23)C1 +CNC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4ccc(Cl)cc4)c(F)cc3F)cc1CC2 +NC(=O)c1nnc(NC2CCCCC2N)nc1Nc1cccc2nn(C(F)F)cc12 +COC1CCN(c2nccc(Nc3cc4c(cn3)ncn4C3CCC3)n2)CC1 +COc1cc(CCCOC(=O)C2CCCCN2S(=O)(=O)c2ccccc2)cc(OC)c1 +Cc1ccc(-c2ccncc2)cc1NC(=O)c1ccc(OCc2ccccn2)cc1 +CCNc1nc(Nc2cc3c(cc2Cl)c(C(=O)N2CCOCC2)cn3C)ncc1C(F)(F)F +Oc1nc(NCc2ccccc2)nc2ccc3c(F)cccc3c12 +O=C(OC1C[N+]2(CCCc3cccs3)CCC1CC2)C(O)(c1cccs1)c1cccs1 +COc1ccc(NCc2ccc(C(=O)Nc3cc(-c4cccs4)ccc3N)cc2)cc1OC +O=C(O)CC(Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)C(F)(F)C(F)(F)C(=O)O +CCOC(=O)c1cc2c(C#Cc3cccc(Cl)c3)nc(C)cn2c1 +Oc1cccc(-c2ccc3c(-c4cccc(O)c4)c(O)ccc3c2)c1 +CC#CCOc1ccc(C(=O)NCC(C(=O)NO)N2CCN(S(C)(=O)=O)CC2)cc1 +O=C(CCN1CCC23CCCCC2C1Cc1cc(O)ccc13)c1cccs1 +CN1C(=C2C(=O)OC(C)(C)OC2=O)Sc2ccccc21 +O=C(Nc1cccc(Oc2ccc3nc(NC(=O)C4CCOCC4)cn3n2)c1)c1cccc(C(F)(F)F)c1 +Oc1ccccc1Nc1nccc(-c2c[nH]c3ncccc23)n1 +COc1cc(-c2cccc(C(=O)NC3CCCCC3)c2)cc(C=O)c1O +Cc1cc(C)c(OCc2ccsc2S(=O)(=O)Nc2onc(C)c2Br)c(C)c1 +CC(C)Nc1c(C(N)=O)nnc2cc(N3CCN(C)CC3)ccc12 +Cn1nc(-c2ccccc2)c2c1NC(=O)C1CCCCC21 +CC(c1nc2c(oc3ccc(Br)cc32)c(=O)[nH]1)N1CCN(C)CC1 +O=C(C1CCN(Cc2ccncc2)CC1)N1CCN(c2ccccc2)CC1 +O=C1NCC2(CCNCC2)c2[nH]c(-c3ccnc(-c4cccc(C(F)(F)F)c4)n3)cc21 +COC1CCC2(CC1)Cc1ccc(C#CC3CC3)cc1C21N=C(N)N(CC(=O)OC(C)C)C1=O +CCOC(O)=C1C(C)=NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cccc(-n2ccnc2)c1 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+CC(C)C1=Cc2ccc3c(c2C(=O)C1=O)CCCC3=O +COc1ccc(CC(N)C(=O)NC2C(CO)OC(n3cnc4c(N(C)C)ncnc43)C2O)cc1 +Cc1nc2ccccc2n1Cc1ccc(CNC(=O)C(O)C(O)C(=O)N2CCCC2c2ccncc2)s1 +CCc1nc(CN2CCN(c3cccc4[nH]c(-c5ccc(C(C)(C)C)cc5)nc34)CC2)cn1C +COc1ccc(Cn2cc(-c3ccc(C(=O)NCCCCN4CCc5cc(OC)c(OC)cc5C4)cc3)nn2)cc1 +CCOC(=O)N1C2CCC1CC(c1ccnc3c(-c4ccc(C)c(O)c4)c(-c4ccncc4)nn13)C2 +COc1cccc(Cn2nc(C(F)(F)F)c(Cc3ccc4c(c3)OCO4)c2OCC(=O)O)c1 +CCC1C(C)CC2C(=O)OC(C)C2C1C=Cc1ccc(-c2cccc(Cl)c2Cl)cn1 +N=C(N)c1ccc(O)c(OCC(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1CC1CCO1 +CCOC(=O)N1CCC(N2CCCC(NC(=O)c3ccccc3C)C2)CC1 +COC(=O)N1CC2CC3CC31C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)N2 +CNc1cccc(CCOc2ccc(CC(NC(=O)c3c(F)cccc3Cl)C(=O)O)cc2)n1 +O=S(=O)(Nc1ncns1)N1CCc2c(cccc2-c2ccc(C(F)(F)F)cc2N2CCOCC2)C1 +CCCCc1ccc2[nH]c(-c3ccc(C(F)(F)F)cc3)c(C=NNC(=O)c3ccccc3)c2c1 +N#CCn1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CCCNCC3)n2)cn1 +Clc1cccc(COc2nc(N3CCNCC3)nc3ccsc23)c1 +COc1c(C)cc(C(=O)N2CCC(CCN3CCC(C(N)=O)(c4ccccc4)CC3)(c3ccc(Cl)c(Cl)c3)C2)cc1C +CCC(C(=O)Nc1ccc2cc(C(=O)NO)sc2c1)c1ccccc1 +CC(C)c1cc(-c2cc(-c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)[nH]n2)cc(C(C)C)c1O +CCc1nc2c(C)cc(C)nc2n1C1CCCCc2cc(-c3ccccc3-c3nn[nH]n3)ccc21 +CCCCOc1ccc(CNc2ccc3c(c2)ncn3-c2ccc(OC)cc2)cc1 +CC(C)CCn1ccc(-c2ccc(OC3CCOCC3)c(Cl)c2)c(C#N)c1=O +O=C1c2ccccc2C(=Cc2c[nH]c3ccccc23)c2sccc21 +Cn1cc(NC(=O)c2cnn3ccc(N4CCNCC4)nc23)c(C(F)(F)F)n1 +Cc1c2ccccc2nc2c1c1cc(NC(=N)N)ccc1n2CCN(C)C +C=C1C(=CC=C2CCCC3(C)C(C(C)OCC(=O)NCC(F)(F)C(F)(F)F)=CCC23)CC(O)CC1O +O=C1Nc2ccc(Cl)cc2C1=C1Nc2ccccc2C1=NO +CN(C)c1ccc(C=CC(=O)C=Cc2c(Cl)cccc2Cl)cc1 +c1cc(C2CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)ccc1OCCN1CCOCC1 +COc1ccc(Cn2c(C)cc3c(c2=O)C=C2CCC(C(C)Cn4cnc(N)c5ncnc4-5)CC2O3)cc1 +Cc1cc(-c2nc(-c3cc(F)c(OC4CNC(=O)C4)cc3Cl)no2)cc(NC(C)C)n1 +N#Cc1cnc2c(Br)cc(NCc3cn(Cc4cccnc4)nn3)cc2c1Nc1ccc(F)c(Cl)c1 +CC1CC(=O)NN=C1c1ccc2nc(-c3ccccc3)oc2c1 +CCOC(=O)c1cn2ccc(-c3noc(C4CCCCN4C(=O)COc4ccccc4)n3)cc2n1 +COc1ccc(-c2ccc(F)c(F)c2)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +FC(F)Oc1ccc2c(c1)CN1CCC2(c2ccc(Cl)c(Cl)c2)CC1 +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CC2CCCN2)CC1 +O=C(Cc1cccc2ccccc12)N1CCC(CNCCCCNCCN2CCCCC2)CC1 +N#Cc1c(-c2ccccc2)cc(N2CCN(C3CCCCC3)CC2)n2c1nc1ccccc12 +CN1C(=O)NCc2c(NC(=O)NC3CC(C)(C)Oc4c(F)cccc43)cccc21 +Cc1cc(F)ccc1NC(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1 +COCCCn1cc(Cl)c2cnc(C(C)N(C(=O)C3CNCCO3)C3CC3)cc21 +CC(=O)Nc1cccc(C2CCN(Cc3ccc(C(=O)c4nc5ccccc5n4-c4ccc(C#N)cc4)cc3)CC2)c1 +Cc1ccc(OCc2cc(C)c3c(c2C)CCN(C2CCOCC2)C3)c(-c2cccc(N3CC4CC4(C(=O)O)C3)n2)c1 +CCN(CC)CCCC(C)Nc1ccnc2cc(OC(F)(F)F)ccc12 +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)CSCC)CC2)cc1 +COc1ccccc1-c1csc2nc(N3CCC(C(N)=O)C3)nc(N3C4CCC3CC(OC)C4)c12 +Cc1ccc(Cl)cc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 +CC1(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)CS(=O)(=O)C2(CCCC2)C(=N)N1 +CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1ccccc1S(C)(=O)=O +Cc1cc(Nc2nc(-c3cccnc3)cn3c(-c4cn[nH]c4)cnc23)sn1 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+CC(=O)C(Cc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 +CN(C(=O)Cn1c(=O)n2c3c(cc(-c4ccccc4)cc31)OCC2)c1ccccc1 +NCC(c1cccc(C(F)(F)F)c1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1 +COc1ccccc1C(=O)Nc1cc2cc(C)c(=O)n(C)c2cc1N1CCCC1 +COc1ccc(O)c(C=NCCc2ccc(S(N)(=O)=O)cc2)c1 +Fc1cc(Oc2cccnc2)cc(-n2nnc(-c3ncc[nH]3)n2)c1 +CC1(C)OC(NC(CCO)c2ccccc2Cl)=NS(=O)(=O)C1(C)C +CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1nc3ccc(F)nc3s1)c1c(O)ccc(Cl)c12 +COC(=O)c1cc2cc(NCc3c(C)cccc3Cl)cnc2[nH]1 +CC(O)CN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +Cc1cc(C)cc(Sc2c(C(C)C)c(=O)[nH]c(=O)n2Cc2ccccc2)c1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCC2C(=O)O)c1 +CN(Cc1ccc(Cl)cc1)C(=O)C(CCN1CCC2(CC1)OC(=O)N(C)c1ccc(F)cc12)c1ccc(Cl)c(Cl)c1 +OCC1CC(O)CCN1CCc1ccc(Nc2nc(-c3ccccc3Cl)cs2)cc1 +COc1ccc(CC(NC(=O)C(NC(=O)C(Cc2ccc(OC)cc2)NC(=O)c2cc(Cl)ccn2)C(C)C)B(O)O)cc1 +C#CCNC(=O)c1cnc(Nc2ccc(C#N)cc2)cc1Oc1c(C)cc(C)cc1C +CCCCCn1c(C)c(C(=O)Cc2ccc(OC)cc2)c2ccccc21 +COc1ccncc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 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+O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2nc(Br)cs2)C2C=CC1C21CC1 +COc1ccc(Cc2c[nH]c3c(OC)c(OC)c(OC)cc23)cc1O +O=C1N(Cc2ccccc2)C(Cc2ccc3c(c2)OCO3)C(O)C(O)C(Cc2ccc3c(c2)OCO3)N1Cc1ccccc1 +COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(Cl)cc4)cc3)c(=O)c2cc1Cl +Nc1ncccc1-c1nc2ccc(-c3cccc(N4CCS(=O)(=O)CC4)c3)nc2n1-c1ccc(C2(N)CCC2)cc1 +CCN1CCCC1CNC(=O)c1c(O)c(C)cc(C)c1OC +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CS(C)(=O)=O)c4ccccc4)ncc23)ccn1 +O=C(Nc1ccc(Cl)cc1)C1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccc(C(F)(F)F)cc2)c1 +Cc1ccc(C)c(NCc2cnc3nc(N)nc(N)c3c2C)c1 +COC(=O)CCCN1C(=O)c2ccccc2NC1c1ccc2c(c1)OCO2 +CCCCC1=NC2(CCCCCC2)C(=O)N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCCCCCCCCCCCCCCC(=O)OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(O)c(O)c1 +Cc1ccccc1NS(=O)(=O)c1ccc2[nH]cc(C(=O)NC3CCCC(C)C3C)c(=O)c2c1 +CS(=O)(=O)c1ccc(-c2nc(SCc3cccs3)cc(C(F)(F)F)n2)cc1 +COC(Cn1c(SCCC(=O)O)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(C)=O)c1)OC +CCOC(=O)CC1N=C(c2ccc(Cl)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +COC(=O)c1cccc2c1C(=O)C=C1N(C(=O)OC(C)(C)C)CC3CC123 +O=C(Nc1ccc(Cl)cc1)c1cccc(O)c1NC(=O)c1sc2ccccc2c1Cl +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4cccc5c4OCCCO5)nc23)N1 +CC(C)CCN(CC(O)C1Cc2ccc(cc2)OCCCCCC(=O)NC(C(C)C)C(=O)N1)NC(=O)NC1CCCCC1 +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCn6ncnc6C5)ncn4)c3c2)cn1 +Cc1nc(O)c2c(ccc3[nH]c(Nc4c(Cl)cccc4Cl)nc32)c1C +O=C(O)c1ccc2c(c1)C(=CCn1cnc3ccc(Cl)cc31)c1ccccc1CO2 +CCOC(=O)C1=C(c2ccc(Cl)cc2)N=C(C)C(=C(O)OCC)C1C=Cc1ccccc1 +N#Cc1cc(F)cc(-c2ccc3c(c2)C2(CCCCC2)C(S)=N3)c1 +O=C1C(N2CC2)=CC(=O)c2c(OS(=O)(=O)C=Cc3ccccc3)cccc21 +CC(C)(CNC(=O)c1ccccn1)NCC(=O)N1CC(F)CC1C#N +c1cnc(N2CCN(CCCNC3=Nc4ccccc4OC3)CC2)nc1 +Cc1cc(-c2c(-c3ccccc3)c3cc([N+](=O)[O-])ccc3[nH]c2=O)on1 +O=c1[nH]c(=O)n(C2OC(COP(=O)(O)CP(=O)(O)O)C(O)C2O)cc1I +CC(=O)NC(C)C#Cc1cnc(Oc2cccc(OCC(C)C)c2)s1 +Clc1cccc2c1CC2CCN1CCN(c2cccc3c2OCCO3)CC1 +Cc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3cc(Cl)ccc32)ccc1OCCN1C(=O)CN(C)C1=O +Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccccc3F)c(=O)c2c1 +CC(NCc1cc2cccc([N+](=O)[O-])c2[nH]1)c1cccc2ccccc12 +COCCN(C)C1CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +CC(C)(C)Cc1nc2c(n1CC1CC1)CCN(S(C)(=O)=O)C2 +COCC(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NC(C)C +Cc1c(C(=O)c2ccccc2F)c2cccc3c2n1C(CN1CCOCC1)CO3 +Cc1ccn2c(NC(C)(C)CC(C)(C)C)c(-c3ccccc3OC(=O)C34CC5CC(CC(C5)C3)C4)nc2c1 +COc1ccc(N(C)C(=O)CNC(=O)C=Cc2ccc(C(F)(F)F)cc2)c(Cl)c1COc1cccc2ccc(C)nc12 +Cc1cccc(C)c1NC(=O)c1ccc2nc(NC(=O)NC(C)(C)C)sc2c1 +Cn1c(=O)c2c(nc(SCCc3cccc(C(F)(F)F)c3)n2C)n(C)c1=O +O=C(CSc1nnc(Nc2ccccc2)s1)NN=Cc1ccc(-c2ccccc2Cl)o1 +CC12C=CC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(O)C(=O)NCc1ccccc1 +CNC(=O)c1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)COC)cc1F +N#CN=C(NCCCCCC(Cc1ccccc1)C(=O)NOC1CCCCC1)Nc1ccncc1 +Cc1ccc(-c2cc(C(=O)NC(C)CO)cc(-n3c(=O)oc4ccccc43)c2)nc1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(C)cc2)[nH]c2ccc(C)cc12 +CCC(CC)c1cc(C)n2nc(-c3cnc(N(C)C)cc3C)c(C)cc12 +O=C1C(=NO)c2cc(F)ccc2N1Cc1cc(F)cc2c1OCOC2 +CN(Cc1ccc(F)cc1)c1cc(O)c(=O)[nH]n1 +COc1ccc(Cn2cnc3c4nc(=O)n(Cc5ccc(Br)cc5)c-4ncnc32)cc1 +NC(=O)C1CCN(c2nc(-c3ccnc(NC4CCOCC4)c3)cc3cnccc23)CC1 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+O=C(Nc1cc2c(c(C(=O)NCc3ccccc3C(F)(F)F)c1)OCC2)c1ccccc1C(F)(F)F +CCS(=O)(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CC3C3CC43)c(F)c2)cc1 +CC(Cc1ccccc1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +Cc1nc(NC2CCCC2)sc1-c1nc(Nc2ccc(N3CCN(C)CC3)cn2)ncc1F +O=C(C[n+]1ccn(C23CC4CC(CC(C4)C2)C3)c1)c1ccc2ccccc2c1 +Cn1cc(-c2cnc3[nH]cc(-c4cnn(Cc5cccc(Cl)c5)c4)c3c2)cn1 +CCCCC(C=NNC(=O)N1CCc2ccccc21)NC(=O)OC(C)(C)C +NCc1c(-c2ccccc2Cl)ccc2ncn(Cc3ccccc3)c12 +CN(C)c1nc2sc3c(c2c(=O)o1)CCN(Cc1ccccc1)C3 +COc1ccc2c(c1)CCN(C)CCc1c([nH]c3ccccc13)C2 +CCCCCCCNC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 +Cn1nc(C(F)(F)F)c(CS(=O)(=O)C2=NOC(C)(C)C2)c1OC(F)F +CCc1cc2c(cc1C1=CCN(C(=O)C3CNC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CC(=O)NNC(=O)CSc1nnc(Cc2csc(NC(=O)CCl)n2)n1NC(C)=O +CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1NC1CCC(O)(CC)CC1 +Cc1ccccc1N1CCc2nc(-c3c(C)cccc3C)nc(N(C)C)c2C1 +CCOCc1nc2c(=O)n(Cc3ccccc3)nc(C)c2c2cc(-c3ccccc3)nn12 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+O=C(CCSc1nc2ccccc2c(=O)[nH]1)NC1CCC(Oc2ccc(Cl)cc2)CC1 +CC(C)COc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +O=C(NC1CCCCC1)N1CCc2cc(S(=O)(=O)Nc3ccc(CCCC4CCCC4)cc3F)ccc2C1 +CC1CCc2cc(C(=O)N(C)Cc3cc4ccccc4[nH]3)ccc2N1C(=O)c1ccc(O)cc1O +c1ccc(Nc2nnc(-c3ccc4[nH]cc(-c5cncc(C6CC6)n5)c4c3)o2)cc1 +O=C(NCCCN1CCCC1)C1C(C(=O)NCc2ccc(Br)cc2)C2C=CC1C21CC1 +CC1(CC(=O)O)c2ccc(F)cc2-c2nc(O)c(O)nc21 +Cc1nc2c3c(c(C(=O)N(C)C)cn2c1C)CCC(c1cccs1)O3 +NC(=O)c1cc(COP(N)(=O)N(CCCl)CCCl)ccc1[N+](=O)[O-] +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(Cn4ccnc4)cc3)ncc2F)c1 +Cc1cc(S(=O)(=O)NC(=O)Nc2ncc(Br)s2)sc1CO +O=C(Nc1ccccc1)N1CCN(Cc2ccc3ccccc3n2)CC1 +O=c1nc(OCC2COCCO2)cc2n1CCc1cc(NC3CCCCC3)ccc1-2 +CCOc1ccc2c(c1)CCN=C2c1ccc(S(N)(=O)=O)cc1 +NC(=O)c1cccc2c(NCc3cccc4ccccc34)ncnc12 +COc1ccc(-c2nc(CCOc3ccc4c(c3)CCC4CC(=O)O)c(C)s2)cc1 +COc1cc(Cl)ccc1-c1cccc2cc(S(=O)(=O)Nc3ncco3)ccc12 +CC=Cc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(CCC)c2)c1 +O=C1N(c2ccc(F)cc2)CCc2nc(COc3ccccc3)c(Cl)n21 +COc1cc(-c2cc(F)cc(Cl)c2)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +O=c1[nH]cnc2c(CN(CCO)CCCO)c[nH]c12 +CC(C)CC(Cc1c[nH]c2ccccc12)(NC(=O)OCc1cc2ccccc2o1)C(=O)NC(C)c1ccccc1 +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CC(=O)O)C(=O)O)cc1 +COc1cccc2nc3c(cc12)CC1(O)C2Cc4ccc(O)cc4C1(CCN2C)C3 +COc1ccccc1N1C(=O)C(=Cc2ccc(O)c(Br)c2)OC1=S +CCCCCCN1C(=O)C(Cc2ccc(-c3cc(OC)c(OC)c(OC)c3)cc2)N(C)C(=O)C1C +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3)CC2)cc1 +O=Cc1ccn(-c2cc3c(cc2[N+](=O)[O-])nc(O)c2nc(C(=O)O)nn23)c1 +CC(O)(CNc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1)c1ccccc1 +CNC(=NC#N)N1CCC(CCN2C3CCC2CC(n2c(C)nc4ccccc42)C3)(c2ccccc2)CC1 +COc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)ccc1-c1coc2ccccc12 +Cc1cc(C)c(Nc2nc(N)nc(NC3CCN(Cc4ccccc4)CC3)n2)c(C)c1 +COc1ccc2oc3nc4ccccc4c-3c(N3CCOCC3)c2c1 +CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(F)ccc3o2)c1)C(=O)O +O=C(Cc1ccc(Cl)cc1)NC(=Cc1ccc(Oc2ccccc2Br)cc1)C(=O)O +CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(=O)O)cc2S(=O)(=O)C4)cc1 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCC(F)(F)F 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+Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1N(C)c1ncnc2cnc(NC3CCOC3)nc12 +COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(Cl)c2)c1 +N#Cc1ccc(OCCN2CCN(CC(=O)Nc3nccs3)CC2)cc1 +OCCn1cc(-c2cc(F)c3ncc(Cc4ccc5ncccc5c4)n3c2)cn1 +CCc1c(O)cccc1C(=O)NC(Cc1ccccc1)C(O)C(=O)N1CSC(C)(C)C1C(=O)NCc1ccccc1C +COc1ccccc1-c1cccc(-c2c(O)nc3cc(Cl)c(C#N)cc3c2O)c1 +CC1(N2CCC(N(c3ccccc3)c3ccccc3)CC2)CCN(C(=O)C2CCCCC2)CC1 +Cc1ccc(NC(=O)c2cc3cc(C)ccc3oc2=O)cc1 +CC(C)(C)OC(=O)N1CCC(C2CCN(c3ccnc(C#N)n3)CC2)CC1 +Cc1nc2cc(CN(c3ncc4ccccc4c3C)S(=O)(=O)c3ccc(C(=O)O)cc3)ccc2s1 +CC(C)(C)NC(=O)NC(C(=O)N1CC2C(C1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(F)F)C(C)(C)C +Cc1cc(-c2nc3cnc(OCC4CC4)cc3n2C(C)c2cccnc2)cn(C)c1=O +C=CCN1CCc2cc(O)cc3c2C1Cc1ccc(O)c(O)c1-3 +CSc1sc(C(=N)N)cc1-c1nc(-c2cccs2)cs1 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CN(S(=O)(=O)C3CNC3)C1)CC2 +CC(C)COC(=O)CNC(=O)C(Cc1ccccc1)CN1CCC(C)(c2cccc(O)c2)C(C)C1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2c(n1CC(=O)O)CCNC2=O +Cn1cncc1C(OCc1c(-c2cc(Cl)cc(Cl)c2)cc(C#N)n(C)c1=O)c1ccc(C#N)cc1 +NCCOc1c(-c2ccc(N3CCOCC3)c(Br)c2)[nH]c(=O)c2cc(F)ccc12 +NS(=O)(=O)c1ccc(NC(=O)Nc2ccc3ccccc3c2)cc1 +CC#CC1CN(S(=O)(=O)c2ccc(N)nc2)CCN1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +COC(=O)C1(C)Nc2c(O)cc3c(c2C1=O)C(CCl)CN3C(=O)c1cc2cc(OC)c(OC)c(OC)c2[nH]1 +CCC1(CCCCN2CCN(c3ccc(F)cc3)CC2)C(=O)Nc2ccc(F)cc21 +Cc1cc(N2CC3CC2CN3C)ccc1-c1ccnc2c(-c3ccc(F)c4[nH]ncc34)c(-c3ccncc3)nn12 +CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2cccn2)CC1 +C#CCN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +O=C(Cc1ccc(NC(=O)c2cscn2)cn1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(=O)C1OC(Oc2ccc(C=C(C)C(=O)NC3C(O)C(O)C4OCOC4C3O)cc2O)C(O)C1O +Cc1cc(C)c(-c2nc3cc(OC4COC4)ncc3[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +Cc1ccccc1C(=O)c1ccccc1NC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O +Cc1ccc2nc(-c3ccc(OCCCN4CCN(c5cccc(Cl)c5Cl)CC4)cc3)cn2c1 +CNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(C4CCC(=O)CC4)c3n2)cc1 +CC(C)CC[n+]1ccccc1C=Cc1ccc(N(C)C)cc1 +Brc1cnc(NCc2ccco2)nc1Nc1cc(C2CC2)n[nH]1 +CCN(CC)CCNc1nc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2[nH]1 +O=C(CCCCN1CCOCC1)Nc1ccc(-c2cccnc2)cc1 +CC1(C)Cc2c(CN3CCC4(CC3)CCN(C(=O)c3ccncc3)CC4)cccc2O1 +CN1C(=O)C2(CC(C)(C)Oc3ccc(-c4cc(Cl)ccc4F)cc32)N=C1N +CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCN(Cc3cccnc3)C2=O)CC1 +O=C1NC(=O)c2c1c(-c1ccccc1)cc1[nH]c3cc(O)ccc3c21 +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)c2cccc(O)c2)CCC3(O)C1C5 +CC(Nc1nccc(N2C(=O)OCC2(C)c2ccccc2)n1)c1ccccc1 +Cc1ccc(-c2nnc(C3CC(F)(F)C3)o2)cc1NC(=O)c1cnc2ccccn12 +CC(C)n1nc(-c2ccc3ccncc3c2)c2c(N)ncnc21 +O=C(CN1CCC(N2C(=O)OCc3cc(Cl)ccc32)CC1)Nc1ccc2ncccc2c1 +COC(=O)c1cc(=O)n(-c2ccc(F)cc2)c(=Nc2ccc(F)cc2)s1 +CC(CCc1cc(-c2ccccc2)no1)(C(=O)NO)S(C)(=O)=O +CN(CCN1CCCCC1)C(=O)N1CCC(C#N)(c2ccccc2)CC1 +C#CCN(Cc1cc2c(O)nc(C)nc2cc1Br)c1ccc(C(=O)NCc2cccnc2)cc1 +N=C(N)c1cccc(C(=O)N2Cc3ccccc3CC2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(-c3cc(OC)cc(OC)c3)o2)cc1 +CCCCSc1nc2c(c(=O)n1CCc1ccccc1)C1(CCCC1)Cc1ccccc1-2 +CN(C)C(=O)Cn1c(N)c(C#N)c2cc(Oc3ccc(NC(=O)CN)cc3)ccc21 +CCOc1nc(NCCc2ccncc2)ncc1-c1nnc(C2CC2)o1 +COC1Oc2ccc(F)cc2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +COc1cccc(-c2noc(C3CN4CCC3CC4)n2)c1 +CN(C)CC1CCN(c2nc(-c3cc(Cl)ccc3OC(F)F)c(NC(=O)c3cnn4cccnc34)s2)CC1 +C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C +CC(C)Cc1c(O)cc(O)c2c1OC(c1ccc(O)cc1)CC2=O +CN(CCN1CCCC1)C(=O)Cc1cccc([N+](=O)[O-])c1 +COc1cc(OCc2nc(-c3ccccc3)sc2C)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CCCCCCOc1c(OC)cc(C(=O)OCCCC[N+](CC)(CC)CC)cc1OC +CCCN(CC1CC1)c1cc([S+](C)[O-])nc2c(-c3ccc(Cl)cc3Cl)c(C)nn12 +C[N+](C)(CCCCNC(=O)c1ccc(Cl)cc1)CCNC(=O)c1nc(Cl)c(N)nc1N +O=C1NCC(=O)N(Cc2ccc(F)cc2)C1Cc1c[nH]c2ccccc12 +Nc1ncnc2c(CN3CC(O)C(C4CC4)C3)c[nH]c12 +O=C(NC1CCOCC1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COCCOc1cc2ncnc(Nc3ccc(NC(=O)C45CC6CC(CC(C6)C4)C5)cc3C)c2cc1OCCOC +COc1cc(N)c(Cl)cc1C(=O)NC1CCCN(Cc2ccccc2)C1 +O=C1NC(=O)C2(CCCN2c2ccc(Oc3ccc(Br)cc3)nc2)C(=O)N1 +CS(=O)(=O)NCCNc1nonc1C(=NO)Nc1ccc(F)c(C(F)(F)F)c1 +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCN(C2CCNC2=O)C1 +N#Cc1cccn1CCC(NS(=O)(=O)c1cccc2[nH]ccc12)C(=O)N1CCC(C(F)(F)F)CC1 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+COc1cc(C(=O)c2coc(-c3ccccc3)n2)cc(OC)c1OC +COc1cc2c(N)nccc2cc1CC(C(=O)O)N1CCC(NS(=O)(=O)c2cnc(N3CCC(F)C3)s2)C1=O +Cc1cc(N2CCN(CCCCc3nc4c(c(=O)n3N)CCCC4)CC2)nc2ccccc12 +CCN1CCc2c(C#N)c(NCc3ccccc3)nc(N(CC)CC)c2C1 +CCc1cccc(NC(=N)Nc2cc(CC)cc(CC)c2)c1 +COC1CN(CC2CCC(COC3CCC(C(=O)O)CC3)N2C(=O)Cc2ccc3nc(Nc4cc(F)ccc4C)oc3c2F)C1 +Cn1cc(C2=C(c3cccc(OCCN)c3)C(=O)NC2=O)c2ccccc21 +CN(C)CCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(F)cc4)cc3)nc21 +CNC(=O)C1OC(n2cnc3c(NCc4cc(Cl)ccc4OCC(=O)O)ncnc32)C(O)C1N +NC(CO)(CCc1ccc(-c2cn(Cc3ccc(F)cc3)nn2)cc1)COP(=O)(O)O +O=C(O)c1ccc(-c2c(C#Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NC4CCC(NC(=O)C5(C(F)(F)F)CC5)CC4)nc23)N1 +Cn1cc(C=C2C(=O)NN=C2c2nccs2)c2cc(F)ccc21 +Cc1ncsc1C(=O)N(Cc1cc(=O)[nH]c2ccc(F)cc12)c1cccc(Cl)c1 +O=C(Cc1nc2ccccc2[nH]1)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +CC12CCC3C(CCC4CC(O)CCC43CO)C1(O)CCC2C1=CC(=O)OC1 +Cn1c(-c2cscn2)c(C2CCCC2)c2ccc(C(=O)NC(C)(C)C(=O)Nc3ccc(C=CC(=O)O)cc3)cc21 +COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccc(-c3cnn(C(C)C)c3)cc1)CC2 +O=C1C(c2ccc(O)cc2)=C(Br)c2ccc(O)cc21 +COc1ccc(C2=C(c3ccc(OC)c(OC)c3)C(=O)OC2)cc1 +CC(NC(=O)c1ccc(C#Cc2cccc(F)c2)cc1)C(C)(C)O +O=C(NO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1ccccc1Cl +CN(C)CCN1CCSc2cc(N=C(N)c3cccs3)ccc21 +NS(=O)(=O)c1ccc(-n2cc(COC3OC(CO)C(O)C(O)C3O)nn2)cc1 +CN(C(=O)c1ccc(F)cc1)C1CCc2c(CC(=O)O)c3ccccc3n2C1 +CC(C(=O)N1CCOCC1)N1CCC(NS(=O)(=O)c2nc3cc(Cl)ccc3s2)C1=O +Cc1c(Cl)cc2c(c1Cl)CCN2C(=O)Nc1cccnc1 +Nc1ncnc2c1c(-c1ccc3[nH]c(Cc4ccc(Cl)c(Cl)c4)nc3c1)nn2C1CCC(N2CCOCC2)CC1 +COC(C)(C)CNc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3c(F)cccc3Cl)cc2[nH]1 +Cc1nc(N2CCC(C(=O)NC(C)C)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +O=CN(O)CC(CC1CCCC1)C(=O)N1CCCC1C(=O)NC(=O)NCCc1c[nH]cn1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(C(=O)c3ccc(Br)cc3)CC2)CC1 +NC(=O)c1cccc2[nH]c(-c3ccc(-c4nnn[nH]4)cc3)nc12 +COc1ccc(C2CC2c2ccc(OC)c(OC)c2OC)cc1 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(C(C)(C)O)ccc3F)nnc12 +CN1CCN(c2cccc(CNc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 +O=c1ccc2c(OCCCCOc3cccc(C(F)(F)F)c3)c3ccoc3cc2o1 +COc1cccc(-c2cc(F)c(Nc3ncccc3C(=O)O)cc2F)c1 +CCN(CC)C(=O)C1CCC2C3CN(C)C4=CC(=O)C=CC4(C)C3CCC12C +CC(c1ccc2ncc(-c3ccc(F)cc3)cc2c1)n1nnc2ncc(-c3ccncc3)nc21 +CC(C)CN(NC(=O)c1cncc(-c2ccccc2)c1)c1nc(C#N)ncc1Br +CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(OC)cc1-2 +O=C(O)c1ccc(N2C(=O)C3ON(c4ccccc4)C(c4ccc(O)cc4)C3C2=O)cc1 +CN1Cc2c(C3=CCN(CC(=O)N4CCC(O)C4)CC3)[nH]c3ncc(F)c(c23)-c2cc(F)ccc21 +c1ccc(-c2cc3c(cn2)ncc2ncn(-c4ccc5nc[nH]c5c4)c23)cc1 +NC1=NCC(Cc2cc(Br)c(N)c(Br)c2)C(N)=N1 +Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4ccc(N5CCOCC5)c(C(F)(F)F)c4)c(Cl)c3)c21 +NC(Cc1ccccc1)C(=O)N1CCCC1CC(=O)NCc1cc(Cl)ccc1-n1cnnn1 +CN(Cc1ccccc1)C(P(=O)(O)O)P(=O)(O)O +CCc1nc(C(F)(F)F)cnc1NC1CCCC1NC(=O)c1ncccc1-c1ncccn1 +CCc1cc2c(cc1N1CCN(CC3(O)CC(C)OC(C)C3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CCS(=O)(=O)N1CCC2(CC1)COC1(OO2)C2CC3CC(C2)CC1C3 +[H]C([H])([H])c1nc(N(C)c2ccc([Se]C)cc2)c2ccccc2n1 +CCOC(=O)C=Cc1cc(-c2ccc(-c3cccc(O)c3)s2)ccc1O +CC(C)C(CC(=O)NO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +O=C(CC(CCCc1ccc(Cl)cc1)C(=O)NC(CC1CCCCC1)C(=O)NCCCCN1CCOCC1)NO +Nc1cnc(-c2ccc(C3CCC3)c(OCCN3C(=O)c4ccccc4C3=O)c2F)cn1 +FC(F)(F)c1cccc(OC(CCN2CCN(c3nsc4ccccc34)CC2)c2ccccc2)c1 +CCCCSc1nc(NC)c2[nH]c(=O)c(=O)n(Cc3ccc(F)cc3)c2n1 +O=C1NCN(c2ccccc2)C12CCN(C1CCOc3ccccc31)CC2 +COc1cc(Cl)cc(OC)c1-c1csc2c(N(CC3CC3)CC3CCOC3)c(OC)nn12 +CC(C)(C(=O)N1CCC(CC(=O)O)CC1)C(NC(=O)c1ccc(C(=N)N)cc1)c1ccc(Cl)cc1 +CCCCCn1c(C)nc2cccc3nc4c(c1c32)Cn1c-4cc2c(c1=O)COC(=O)C2(O)CC +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(CNc2ccccn2)Nc2ccccc2C(=O)c2ccccc2)cc1 +O=C1c2cc([N+](=O)[O-])ccc2OCN1CCO[N+](=O)[O-] +CC(C)c1nc(C(=O)NC2CCN(C(C)C)CC2)c2ccccn12 +COc1ccc2c(c1F)C(=O)N(CC1(c3cc4nc(N5CCC(N(C)C)CC5)ccc4o3)NC(=O)NC1=O)C2 +COC1Cc2sc(-c3ccc(C#N)cc3)cc2C2(CCN(Cc3ccccc3)CC2)O1 +CCC1CCCN1Cc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +Cc1ccc(Nc2nc(Nc3ccccc3)nc(NC(C)C)n2)cc1 +C=CC(=O)N1CCc2ccc(-n3c(=O)ccc4cnc5ccc(-c6cnn(C)c6)cc5c43)cc21 +c1ccc2c(c1)CCC1CN(Cc3ccc4ccccc4c3)CCC21 +Cc1ccc(C(Nc2c(Nc3cccn(C)c3=O)c(=O)c2=O)C2(C)COC2)o1 +CCOC(=O)N1CCC(N2CCC2C(=O)N2CC(Sc3ccccc3OC(F)(F)F)CC2C(=O)NC2(C#N)CC2)CC1 +c1ccc2nc(CCc3cn4c(-c5ccc(-c6nnn[nH]6)nc5)cnc(N5CCOCC5)c4n3)ccc2c1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3cc(F)ccc3[nH]2)n1 +CCCC1CC2OC(=O)c3c(cc(OC)c(OC)c3O)C2O1 +CNC(=O)CCc1cccc(-n2ccc3cnc(Nc4cc(OC)c(OC)c(OC)c4)nc32)c1 +COc1cccc(-c2cnc(Nc3ccc(-c4cnco4)c(OC)c3)o2)c1 +CSc1ccc(C(=O)NC2CCC(NC(C)C)CC2NC(=O)CNC(=O)c2cc(C(F)(F)F)ccc2N)cc1 +O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)N1CCN(C2CCC(O)CC2)C(=O)C1 +CC(NC(=O)c1ccc(-c2nc(C3=CCOCC3)cnc2N)cc1F)c1cc(F)cc(S(C)(=O)=O)c1 +COCCCc1ccc(Cl)c(CN(C(=O)C2=C(c3ccc(OCCOc4c(Cl)cc(C)cc4Cl)cc3)CCNC2)C2CC2)c1 +N#Cc1ccc(C(O)(c2ccc(C(F)(F)F)cc2)c2cccnc2)c(F)c1 +CNC(=O)c1cccc(OCCCCN2CCN(c3cccc4sccc34)CC2)c1 +CCOCCN1CCN(CCCNC(=NC#N)c2ccccn2)CC1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3cc4cc[nH]c4cn3)c2)c2cncnc21 +C=C(C)C1Cc2c(ccc(C(=O)n3c(C)nc4ccccc43)c2OC)O1 +O=S(=O)(Nc1ccc2nccc(N3CCNCC3)c2c1)c1cccc2c(Cl)cccc12 +Cc1ccccc1Nc1nc(N)nc(Nc2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)n1 +COc1ccc2c(c1)Oc1ncn3nc(C)nc3c1C2c1ccc(Cl)cc1 +Nc1ccccc1Nc1ccc2c(c1)CCc1ccccc1C2=O +CNCC(O)C(c1ccccc1)n1ccc2cc(F)ccc21 +CC(=O)NC1CCC(NC(=O)c2cnc(-n3ccc4cncnc43)cc2NC2CCOCC2)CC1 +COc1cccc(C2CCC(N3CCN(c4cccc5ccccc45)CC3)CC2)c1 +CCCc1cc(Oc2ccc(O)cc2)ccc1OCCCOc1cccc(C2SC(=O)NC2=O)c1 +CC(C)CC(NC(=O)Cc1ccc2c(c1)Nc1ccccc1S2)C(=O)NC(CC(C)C)C(=O)NC1CCOC1O +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(Cl)cc3OC(C)C(=O)NCC(F)F)c12 +CC1(c2ccccc2)CCN(CC2CCc3cccnc3C(O)C2)CC1 +COc1cc(OC)c(Nc2ccc3nnc(-c4ccccc4)n3n2)cc1Cl +CCNC(=O)c1ccc(Oc2cccc(CC(=O)O)c2)c(NS(=O)(=O)c2ccc(C)cc2)c1 +C[n+]1c2n(c(=O)c3ccccc31)CCc1c-2[nH]c2ccccc12 +CCNC(=O)c1ccc(-c2ccc(C(=O)N(C3CC3)C3CCN(C(=O)OC(C)(C)C)CC3)cc2)cc1 +CCc1nc(CN2CC(C(=O)O)C2)ccc1-c1cnc(-c2ccc(CC(C)C)c(C)c2)s1 +C=CCN1CC(C)N(C(c2ccc(C(=O)NC(CC)CC)cc2)c2cccc(OC)c2)CC1C +COC1C(F)CN(C(=O)Cn2nc(C(N)=O)c3ccccc32)C1C(=O)NCC1CC1(Cl)Cl +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3OC)ncc2C(F)(F)F)c1 +COc1ccc(C(=O)Nc2ncc(-c3ccc(C(=O)O)c4ccccc34)s2)cc1 +COc1ccccc1N1CCC(C(=O)Nc2ccc(OC)c(N3CCN(C)CC3)c2)CC1 +CCN(CC)c1ncc(N(CC)c2ccc(F)cc2)c(NC(Cc2ccc(OC(=O)N3CCCC3)cc2)C(=O)O)n1 +CC1CN(CC(=O)Nc2ccc(-c3cccn4c(=O)cc(N5CCOCC5)nc34)c3sc4ccccc4c23)CC(C)O1 +Cc1nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)cc(N2CCOCC2)n1 +NS(=O)(=O)c1ccc(NC(=S)NC(=O)Nc2ccc(CC(Cl)Cl)cc2)cc1 +O=C(CCN1CC2CC(C1)c1cccc(=O)n1C2)c1ccccc1 +CCn1nc(Nc2cccc(C)c2)c2c1CCN(C(C)=O)C2 +Cc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(=O)O)C3=O)cn2)cc1 +CC(C)CC(C=O)NC(=O)C(CCS(=O)(=O)c1ccc2ccccc2c1)CC(C)C +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(F)cc5)CC4)cc3)cc2n(C)c1=O +COc1ccc(C2(O)CCN(C(c3ccccc3)c3ccccc3)CC2)cc1 +CN(C)CCN1C(=O)c2c(c3c4ccccc4[nH]c3c3ccccc23)C1=O +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=CC2CCCCC2)[nH]c1=O +Cc1oc(-c2ccccc2)nc1CCOc1cccc(C2CN(C(=O)OCC(C)C)CCC2CC(=O)O)c1 +O=C(C=Cc1ccc(Cl)c(Cl)c1)c1ccnc2ccccc12 +NC(=O)c1cccc2c(Nc3ccc(OCc4ccccn4)c(Cl)c3)ncnc12 +CCNC(=O)N1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +COc1cc(Oc2c(C3CCC3)ccc(-c3cnc4[nH]ccc4n3)c2F)ncn1 +Cn1c(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(-c2ccc(F)cc2)c2cccnc2c1=O +COc1cc(C(=O)Nc2cc(C(=O)NC3CCCCC3)ccc2-c2ccc(Cl)cc2)cc(OC)c1OC +CC(=C(C#N)C(=O)Nc1ccccc1)c1cn(CC(=O)O)c2ccccc12 +Cc1cc2c(cc1N1CCC(N3CCOCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +COc1cccc(Cn2cccc(C=CC(=O)NO)c2=O)c1 +O=C(O)C1CCCCC1NCc1cc([N+](=O)[O-])cc2nc(O)c(O)nc12 +CC(C)Oc1ccc(S(=O)(=O)N2CCN(c3cc(F)cc(OCC(=O)O)c3)CC2)cc1 +CC(C)Oc1ccc(Nc2cc(=O)n(Cc3ccccc3)cc2C(O)c2ccc(Cl)cc2)cc1Cl +Cc1cc(=O)n(-c2ccc(Br)cc2F)nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)cc1 +CSc1ncc(C(=O)N2CCN(C)c3ccccc32)c(Oc2cc(Cl)ccc2Cl)n1 +COC(=O)CCc1nc(C)nn1-c1cc(N2CC(c3nc4ccccc4n3C)C2)nc(C)n1 +CCCCCCC[n+]1c(C=Cc2ccc(N(C)C)c3ccccc23)sc2ccccc21 +CN(C)c1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1 +COc1ccc(C2(C(=O)c3ccc(C(=O)c4ccc(N(C)c5ccc(Cl)cc5)cn4)cc3C(=O)O)CC2)cc1 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1cccc2nsnc12 +CC(C)c1cccc2c(-c3ccccc3)cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)nc12 +Cc1nc(CNC(=O)c2cc3cc(Nc4nccc(-c5cn(C)cn5)n4)cc(C)c3[nH]2)cs1 +CN1CCN(Cc2cc3nc(-c4ccc(NC(=O)Nc5ccncc5)cc4)nc(N4CC5CCC(C4)O5)c3s2)CC1 +COc1ccc(OC(CCN2CCN(c3ccc(Cl)cc3)CC2)c2ccccc2)cc1 +COC1C(O)C(O)C(Oc2ccc3cc(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C +O=C(O)CCc1c(C=C2C(=O)Nc3ccc(S(=O)(=O)Cc4ccc(F)cc4)cc32)[nH]c2c1C(=O)CCC2 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C1=CCOCC1 +Cc1ccccc1CC(NC(=O)c1cccnc1)C(=O)NCCCCC(CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 +Cn1c(=O)c2cc(C#C[Si](C)(C)C)ccc2n2cnc(C(=O)OC(C)(C)C)c12 +COCCNc1ccnc(NC(=O)c2csc(-c3nncn3C(C)C)n2)c1 +O=C(c1cccnc1Oc1ccc(Nc2ccccn2)cc1)N1CC=CC1 +COc1cc(CN(C)CCc2ccccc2)ccc1OCc1ccccc1 +CC(C)CC(NCCc1ccc(-n2c(N)c(C(=O)c3ccc(F)cc3F)ccc2=O)cc1)C(=O)OC(C)(C)C +Cc1ccc(C(=O)Nc2cc(Cl)ccc2OCC(=O)Nc2ccc(S(N)(=O)=O)cc2C)cc1C +Cc1cccc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)c1 +COc1ccc(C(NC(=O)c2cc(F)c3cnc(Nc4ccnn4C)nc3c2)c2cnn(C)c2)cc1F +CC1(COc2ccc(Cl)cn2)CN(C(=O)C2CCN(c3ccc(F)cn3)CC2)CC1c1ccc(Cl)cc1 +CC(C)N1CCN(C(=O)NCc2ccc(Oc3ccccc3)cc2)CC1 +CC(OC1CCn2c(O)nnc2CC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Nc1nc2c(c(=O)[nH]1)NCN2CC(CO)OCP(=O)(O)O +CCn1c2ccccc2c2cc(NC(=O)CCc3ccncc3)ccc21 +CCCCCCCCCCCCCCCNOC(=O)CC1OCC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1 +CCCCCCCCCCCCn1nnc(C(NC(=O)c2c(Cl)cccc2Cl)c2ccccc2)n1 +NCCC1CNC(=O)c2cc(-c3cccc(OC(F)(F)F)c3)c(-c3ccc4c(c3)OCO4)n21 +Cc1c(NS(=O)(=O)c2ccc(CCCC3CCN(C)CC3)cc2)c(CCc2ccccc2)nn1C +CN1CCc2cc(-c3ccc4oc5c(-c6ccccc6)nc(=O)n(CCN6CCC(F)(F)C6)c5c4c3)ccc2C1 +NC1CCC(NC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)C1 +Cc1ccc(CCCCN2CCC(C(O)c3ccccc3)CC2)cc1 +CNC(=O)c1ncncc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +CC(C(=O)NCCCc1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCCCc1nc2cccc(C(=O)NC(C)C)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C1Nc2ccc(F)cc2C1CCCCN1CCN(c2ccc(Cl)cc2)CC1 +O=C(NCc1ccccc1)C1CNCC1C(=O)NCc1ccccc1 +O=C(NCC1(O)CCCCCC1)c1cc(-c2ccccc2C(=O)O)ccc1Cl +Cc1ccc(Nc2nnc(SCc3ccccc3F)[nH]2)cc1 +N=C(N)c1cccc(Cn2c(C(=O)NCCc3ccc(Cl)c(Cl)c3)cc3c(O)cccc32)c1 +CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3cnc4ccccc4c3)C2=O)c(F)c1 +OCC1OC(n2cc(Cc3ccc(C4CCCC4)cc3)c3ccccc32)C(O)C(O)C1O +CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)c1SCC +C=C(COC(=O)CCCCC[n+]1ccccc1)COC(=O)NCCCCCCCCCCCCCCCCCC +CC(c1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1)N1CCN(C2CCCCC2)CC1 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc5cc(C(N)=O)ccc5n4C)c3)cc2C1 +Cc1c[nH]c2ncnc(N3CCC(C)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12 +CC(C)c1cccc(-c2cccc3nc(NC(=O)C4CC4)nn23)c1 +COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCCN1CCCC1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c1ccc(Cl)cc1 +C#CCNC(=O)c1ncn2c1Cn1ncnc1-c1cc(F)ccc1-2 +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)NNC(=O)Nc4ccccc4)cccc2-3)cc1 +CCC(CC)c1cc(C)nn2c(-c3sc(N4CCOCC4)nc3Cl)c(C)nc12 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NC5CC5)s4)nc23)N1 +CCc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 +O=C(O)CC1CCC(c2ccc(C(=O)Nc3nnc(C4CCCC4)s3)cc2)CC1 +c1ccc(C(Nc2nnc(-c3c[nH]c4ncccc34)o2)C2CC2)cc1 +O=C(O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccc(Br)cc2F)n1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 +Cn1nccc1C(NC(=O)c1ccc2cnc(NC3CCOCC3)nc2c1)c1ccc(Cl)c(F)c1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3cc4occc4[nH]3)c2)c2cncnc21 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NS(C)(=O)=O)c1=O)C(=O)C(F)(F)F +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CCNCc3ccccc3)c2=O)c1 +CCn1nnc(C2OC(n3cnc4c(NC5CCCO5)ncnc43)C(O)C2O)n1 +COCC(C)Oc1cc(Oc2ccc(OC)cc2)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 +CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4cccnc4C3=O)CC2)CC1 +O=C(O)c1ccc(CNC(=O)c2cc(F)cnc2Oc2ccc(F)cc2)cc1 +Cn1cc(-c2cnc3ccc(NC(=O)Nc4ccccc4)nc3c2)cn1 +COc1ccccc1N1CCN(CCCCN2CSC(C)(C)C2=O)CC1 +O=C(NO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1ccc2ccccc2c1 +O=C(NC1CCCC1)c1noc(-c2ccc(Br)cc2)c1Br +CCN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1)c1cccc(C)c1 +CCC(CC)[N+](C)(C)Cc1ccc(NC(=O)C2=Cc3cc(-c4ccc(C)cc4)ccc3OCC2)cc1 +c1csc(CN2CCN(c3nc4ccccc4n4cccc34)CC2)c1 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+CN(Cc1ccc(-c2nccnc2NS(=O)(=O)c2ccccc2C(F)(F)F)cc1)c1ccc(F)cc1 +O=S(=O)(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1cc(Br)c(Br)s1 +Fc1ccc(F)c(COC2C3CCN(CC3)C2C(c2ccccc2)c2ccccc2)c1 +Cn1nc(CC(=O)Nc2ccc3ccccc3c2)c2ccccc2c1=O +O=C(NO)c1cc2n(c1)CCN(C(=O)c1cc3ccccc3s1)C2 +CCCN(C)C1C=C(C(=O)O)CC(N)C1NC(C)=O +O=C(C(O)c1cccc(Cl)c1)N1CCC(Nc2ccc3[nH]ncc3c2)CC1 +O=C(C=Cc1cccc(F)c1)NCCCCNc1c2ccccc2nc2ccccc12 +Cn1c(=O)c2c(cc(-n3cc(-c4ccc(Cl)cc4)nn3)n2C)n(C)c1=O +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3C(F)(F)F)CC2)cc1 +O=C(NC1C2CC3CC(C2)CC1C3)N1CCC2(CC1)CC(CCO)c1cccc(Br)c12 +Cc1cccc(-n2ncc(C)c2-c2cc3cnccc3s2)n1 +CCCCCCCCCCCCN(C)C(=O)Cn1cc(Cc2cnc(=O)n(CC(=O)NC)c2)c(=O)nc1SCc1ccc(F)cc1 +Cc1ccc(N2CCc3cc(O)ccc3C2(C)c2ccc(C=CC(=O)O)cc2)cc1 +CCN1C(C(=O)NC(C=O)CC(C)C)Cc2cc3c(cc2S1(=O)=O)OCCO3 +O=C(Nc1cc(F)c(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1Cl)Nc1ccccc1Br +Cc1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(C)n1 +OCC1OC(OC2C(CO)OC(Oc3ccc(CCc4ccc(O)cc4O)c(O)c3)C(O)C2O)C(O)C(O)C1O +Cc1ccnc(NC(c2ccc(F)cc2)c2cc(Cl)c3cccnc3c2O)c1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3N(C)S(C)(=O)=O)n1)CCN2 +COc1cc(-c2cccc(F)c2)ccc1-c1ncnc2cc(S(=O)(=O)Nc3ncns3)ccc12 +CNc1nc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc2[nH]1 +CC(C)(O)CNC(=O)c1ccncc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1 +COc1ccc(-c2nc(-c3cc(C)nc(C)c3)c3n2CC(C)OCC3)cc1OC(F)(F)F +Cc1cc(Nc2nccc(-c3ncn(C)c3C)n2)cc2cc(C(=O)N(C)C)[nH]c12 +CC(C)CS(=O)(=O)Nc1ccncc1-c1ccc(C#N)c2ccccc12 +CCCCCCCCCC=CC=CC(SCCC(=O)O)C(O)c1cccc(-c2nn[nH]n2)c1 +COCCN1CCN(c2ccc(-c3ncc4c(n3)N(CCCN3CCOCC3)CC4)cc2)CC1 +CCNC(=O)Nc1nc2cc(-c3ccc(OCCN(C)C)nc3)c(OCC3CCOC3)nc2s1 +Cc1ccc(C(=O)Nc2ccc3c(c2)C=CS(=O)(=O)O3)cc1 +CCCCCCCCCCOc1ccc2c3cc[n+]4nc(CC)c(CC)cc4c3n(C(=O)OC(C)(C)C)c2c1 +Cc1ccc(S(=O)(=O)NC2CNCC(C(=O)NCC(c3ccccc3)c3ccccc3)C2)cc1 +O=C(Cn1nnc(-c2ccncc2)c1-c1ccccc1)Nc1ccc(-c2ccccc2)cn1 +COc1c(Nc2ncc(Cl)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc2c1CCC(N1CCOCC1)CC2 +CN(c1ccc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)nc1)C1CCCNC1 +Oc1nc2c(Cl)cc3c(c2[nH]1)C1c2ccccc2CCC1NCC3 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+O=C(Nc1ccncc1)C(=O)c1cn(Cc2ccco2)c2ccccc12 +CCn1nc(C#Cc2cc(C(=O)Nc3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)ccc2C)c2c(N)ncnc21 +CCN(Cc1ccnc(C)c1)C(=O)Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cc(N4CCOCC4)ncn3)c(F)c2)no1 +Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(-c2ccccc2C(F)(F)F)n1 +O=C(c1ccc(-c2ccc(O)c(Cl)c2)cc1)c1cccc(O)c1 +Cc1cc(CC(C)C(=O)N2CCN(c3ccc(C(F)(F)F)cc3C(N)CC(C)C)CC2)ccc1Cl +Cc1ccc(Oc2ccc(Nc3nccc(N)n3)cc2)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(C)c4ncccc4C)ncc23)ccn1 +CCC(C)N1C(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +CCCCCCCCC(=O)Oc1ccc2[nH]cc(CCN(C)C)c2c1 +CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)O)cc3)[nH]c2c1=O +COc1ccc2c(c1)c1c(n2S(=O)(=O)c2ccc(C)cc2)CCCC1CN(C)C +COc1ccccc1N1CCN(CCCCN2CCc3cc(C#N)ccc3C2=O)CC1 +COc1cc2nc(N3CCN(C(=O)c4ccco4)C4CCCCC43)nc(N)c2cc1OC +COc1ccc(-c2cc3c(C)nc(N)nc3n(C3CCC(OCCO)CC3)c2=O)cn1 +C#CCOC(=O)Nc1ccc(Cl)c(-c2nc3ccccc3o2)c1 +CCCCCCCNC(=O)Oc1cccc(CN(C)CCCOc2ccc3c(=O)cc(-c4ccccc4)oc3c2)c1 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+CC(C)OC(=O)N1CCN(C2c3ccc(Cl)cc3C(C(O)c3cncn3C)=Cc3cccnc32)CC1 +Cc1ccc(C)n2nc(CCc3cn(C)c(-c4ccco4)n3)nc12 +O=C(Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)c(Cl)c1)c1ccccc1F +N=C(N)N1CCC(CC(=O)CN2CCCCC(NS(=O)(=O)c3ccccc3)C2=O)CC1 +COc1c(C(C)C)cc2c(c1O)C1(C(=O)O)CCCC(C)(C)C1CC2 +CCc1cc(-c2c[nH]c3ncc(-c4ccccc4)cc23)ccc1C(=O)O +NC1CCc2ccc(CNS(=O)(=O)CC3CC3)cc2C1Cc1ccccc1 +CCC(C)Oc1ncnc2[nH]cc(C=CC(N)=O)c12 +FC(F)(F)Cc1nnc2ccc(-c3ocnc3-c3ccccc3)cn12 +CCCCCCOc1ccc(NS(=O)(=O)c2ccc3c(c2)CCN(CCc2ccc(C(C)(C)CO)cc2)C3)c(F)c1 +CCOC(=O)C(=O)OC1(C)CCC2CC1OOC2(C)CS(=O)(=O)c1ccccc1 +COc1ccc(C=CC(=O)c2cccc(Nc3ncnc4cc(OC)c(OC)cc34)c2)cc1OC +Cc1ccccc1C1CCCN(Cc2ccc(C(=O)N(CCc3ccccc3Cl)C3CCNC3)cc2)C1 +CC(C)(C)NC(=O)N1CCC(NC(c2ccc(Cl)cc2)c2cccnc2)CC1 +O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)c1 +OC(C(COCc1ccccc1F)OCc1ccc(F)cc1)C(O)C(COCc1ccccc1F)OCc1ccc(F)cc1 +O=C(NC1CCN(CCCCc2ccccc2)CC1)c1cccc2ccccc12 +COc1ccc(C(C)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O 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+O=c1c2cc([N+](=O)[O-])ccc2[se]n1CCn1[se]c2ccc([N+](=O)[O-])cc2c1=O +CC1CCCC(Nc2ncnc3c2nnn3Cc2ccccc2)C1 +Oc1ccccc1CNCCCCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2 +Cc1c(NC2CCC(N)CC2)nc2ccnn2c1Nc1ccc(F)c(Cl)c1 +CC(=O)Nc1cc(C(C)(C)C)c(SC2=C(O)OC(CCc3ccccc3)(C(C)C)CC2=O)cc1C +Cc1ccc(C(C)(C)C)c(OCCCCCCN2CC(O)C(O)C(O)C2CO)c1 +CCOC1CCC(CS)(C(=O)NC(Cc2ccc(OC)cc2)C(=O)Nc2ccccc2)CC1 +O=c1[nH]nc(Cc2cccc(NS(=O)(=O)c3cccs3)c2)c2c1CCCC2 +O=C(O)C(Oc1ccc(-c2ccc(-c3c(Cc4ccc(O)cc4O)sc4ccccc34)cc2)cc1)c1ccccc1 +CC(C)N1CCC(n2cnc(-c3ccc(F)cc3)c2-c2ccnc(N)n2)CC1 +CNCCN(C)c1cc(F)cc(CCc2cc(C)cc(N)n2)c1 +NS(=O)(=O)OCC1CC(Nc2ncnc(NC3CCc4ccccc43)n2)C(O)C1O +COCCCOc1cc(C(=O)N(CC2CNCC2OC(=O)NCc2ccccc2)C(C)C)ccc1OC +COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OCC1CN2CCCCC2CO1 +COc1cccc(-c2nc3c(C(=O)Nc4cnccc4C)ccnc3[nH]2)c1 +Cc1ccccc1C(Oc1cc(OCc2ccc3ncoc3c2)ccc1C#N)C(=O)O +CC(Cc1ccc(F)c(F)c1)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O +O=C(O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(CCCCC2)C1 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+O=C(OC1(C2COCC(CC3CC3)N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC2(CCN2)CC1 +COc1cc(OC)c2cc(C(=O)c3cnn(-c4ccc5[nH]c(C)nc5c4)c3N)[nH]c2c1 +Cc1n[nH]c2ccc(-c3nnc(NCC(N)Cc4ccccc4C(F)(F)F)s3)cc12 +OCC1C(O)C(O)C(O)CN1CCCCCOCc1ccc(-c2cccnc2)cc1 +C=C1C(O)CC(=CC=CCC(C)(C)CC(C)CCCC(C)(C)O)CC1O +COc1cc(CCNCc2ccc(N3CCN(C)CC3)cc2)c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1 +O=C(Nc1cccc(Nc2ncccc2-c2ncnc3[nH]cnc23)c1)C1CC1 +COc1ccc(-c2nc3cc(-c4csc(C(=O)O)c4)cnc3[nH]2)cc1 +CCCN(CC)C(=O)C(NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1)c1ccccc1 +COc1ncc(-c2cc3c(C)nc(N)cc3n(C3CCCC3)c2=O)cn1 +N=C1NC(c2cccc(-c3cncc(Cl)c3)c2)(C2CC2)C(=O)N1C1CCOCC1 +COCC(NC(=O)Nc1cc2[nH]nc(N)c2cn1)c1ccccc1 +O=C(CC1CCc2ccccc2N1S(=O)(=O)c1ccc(Cl)c(Cl)c1)Nc1ccc(N2CCC(N3CCCCC3)CC2)cc1 +CCOc1ccc(Cl)cc1OCC1CN(Cc2ccc(Cl)cc2)CCO1 +N#Cc1c(-c2ccccc2C(=O)O)cc(-c2ccccc2O)nc1N +c1cc(-c2nn(C3CCCNC3)cc2-c2ccc3c(c2)Cc2c[nH]nc2-3)ccn1 +COc1cc(CCC(=O)NCCCCCC(=O)NNc2c3c(nc4ccccc24)CCCC3)cc(OC)c1OC +Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2c(Cl)cccc2Cl)cc2[nH]c(C3CCCO3)nc12 +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(Cl)cc3Cl)ncnc21 +O=Cc1cn(Cc2cccc(C(F)(F)F)c2)c2ccccc12 +Cc1noc(-c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)n1 +Cc1cncc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)c1 +O=c1c(-c2cccc(CO)c2)cccn1C(CN1CCC(O)C1)c1ccccc1 +COc1cc2c(cc1OC)-c1c(-c3cocn3)ncn1CC2 +O=C(NC(c1ccc(Cl)c(Cl)c1)C1CCN(Cc2ccc(C(F)(F)F)cc2)CC1)c1ccc2cnccc2c1 +COc1n[nH]c2cc(OCCNCC(O)c3cccc(NS(C)(=O)=O)c3)ccc12 +Cc1ccc(CNC(=O)CC2c3ccccc3N=C(N3CCN(CCN(C)C)CC3)N2c2ccc(-c3ccccc3)cc2)cc1 +Cn1cc(-c2ccc3nc(NC(=O)c4cnn(C)c4Cl)cn3n2)c(-c2ccc(F)cc2)n1 +Cc1nnc2c(NC3CCN(S(=O)(=O)CCCN(C)C)CC3)cc(N(C)Cc3ccccc3)nn12 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3cccc(F)c3)cc2)C1COC(C)=O +Cc1nc(NC(C)c2cccc(OCCCN(C)C)c2)cc(-c2ccc3ncsc3c2)n1 +Nc1cnc(-c2ccc(C3CCC3)c(Oc3nccc(C(F)(F)F)n3)c2F)cn1 +Oc1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)C1=C2CCOc2ccccc21 +CC(=O)N(Cc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1)Cc1cn(C)nn1 +COc1cccc(C2c3ccc4cccnc4c3Oc3nc4c(c(N)c32)CCCC4)c1 +O=C1Nc2cc(NC(=O)c3c[nH]cc(-c4ccccc4F)c3=O)ccc2C1=Cc1ccc[nH]1 +Brc1ccc(C2=NN(c3nc(-c4ccc(Br)cc4)cs3)C(c3ccc4c(c3)OCO4)C2)cc1 +COc1cc2c(cc1OC)CC(CC1CCN(CCCNc3c4c(nc5cc(Cl)ccc35)CCCC4)CC1)C2 +Clc1ccc(OCCc2ccccc2)c(CCN2CCN(c3ncccn3)CC2)c1 +c1ccc(C(OCCN2CCN(CCCc3ccco3)CC2)c2ccccc2)cc1 +CCCn1c(=O)c2nc(-c3ccc(OCc4nc(-c5ccccc5C(F)(F)F)no4)cc3)[nH]c2n(CCC)c1=O +CN(C)CCN=C(S)Nc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +COc1cc(C(=O)N(C)C)cc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1 +O=C(O)CCCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21 +CC(C)CC(NC(=O)CCOc1ccc2ccccc2c1)C(=O)NC1CC(=O)OC1O +NC(=O)C(CC1CC1)NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1 +Cc1ccc(C)n2nc(CCc3nc(-c4ccsc4)nn3C)nc12 +COc1cc(C=NNC(=O)C(OC)c2ccc3c(c2)OCCO3)ccc1C(F)(F)F +CC(C)CC(N)CCN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1 +Cc1ccc(NC(=O)CC(C)C)cc1-c1ccc(C(=O)NCC2CC2)cc1 +COc1ccccc1-c1noc(-c2ccc(N3CCOCC3)c(C(F)(F)F)c2)n1 +O=c1cc(-c2ccccc2)nc(NC2CCCCC2)[nH]1 +CS(=O)(=O)c1cccc(Oc2cccc(-c3c(-c4ccccc4)nc4c(C(F)(F)F)cccn34)c2)c1 +COc1ccc(CN(C)C(=O)C2(c3ccc(Cl)c(Cl)c3)CC2CN2CCC(NC(C)=O)(c3ccccc3)CC2)cc1 +CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)c2cnn(C)c21 +Nc1nc(N)c2c(Sc3ccc(N4CCOCC4)cc3)cccc2n1 +CNC(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)nnc1Cl +O=C(NCC1NCCc2ccccc21)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CC(Nc1cccc(Cl)c1)c1cc(C(=O)NCCN(C)C)cn2c(=O)cc(N3CCOCC3)nc12 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4nnn(-c5nonc5N)c4-c4ccccc4)c3)cc2C1 +CC(C)Cc1ccc(C(C)c2nc3ccccc3n2Cc2ccccc2C(F)(F)F)cc1 +CN(C)C1CCN(c2cc(Nc3cc(C4CC4)[nH]n3)nc(-c3cccc(C#N)c3)n2)C1 +CN1C(=O)NC(=O)C12Cc1ccc(NC(=O)CN(Cc3ccccc3)C(=O)C(C)(C)C)cc1C2 +O=C(c1ccccc1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21 +COCC1OC(=O)c2coc3c2C1(C)C1=C(C3=O)C2CC(Br)C(=O)C2(C)CC1OC(C)=O +FC(F)(F)c1cccc(NC(=S)N2CCCC2c2ccncc2)c1 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OC2C3CC4CC(C3)CC2C4)cc1F +Cc1cc2c(N3CCN(CCc4ccc5c(c4)NC(=O)CO5)CC3)cccc2[nH]1 +CCOCCC1(Oc2ccc(Oc3ccc(-c4nnco4)cc3)cc2)C(=O)NC(=O)C(N)C1=O +Cc1ccc(-c2cc(NCC(O)CO)c3ccccc3n2)cc1Cl +Cc1ccccc1CC(NCP(=O)(O)O)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)O +NS(=O)(=O)c1cc2c(s1)C(O)CCS2(=O)=O +O=C(Cc1cnc[nH]1)NC(CCCc1ccccc1)C(=O)Nc1ccc(Oc2ccccc2)cc1 +COCCCCn1c(=O)cc(Nc2ccc(C)c(Br)c2)[nH]c1=O +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5sc(C(N)=O)cc5c4)CC3)c2c1 +CCCCCCC(C(=O)N1CC(Oc2cccnc2)CC1C(=O)O)n1cnc(NC(=O)c2ccccc2S(=O)(=O)O)c1 +O=C1c2sc(COc3ccccc3)nc2CCN1c1ccc(F)cn1 +CC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1ccc(N2CCC(N(C)C)C2)nc1 +Nc1ncc(-c2ccc(CN3CCOCC3)s2)cc1C(=O)Nc1ccnc2ccoc12 +Cc1c(NC(=O)c2ccc(N(C)C)cc2)cccc1-c1cn(C)c(=O)c(Nc2ccc(C(=O)N3CCOCC3)cc2)n1 +CCCOc1ccc(NC(N)=S)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 +O=C(c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1)N1CCN(c2ncccn2)CC1 +COc1ccc(-n2nc(C#N)c3c2C(=O)N(c2ccc(C4(CN5CCOCC5)CC4)cc2)CC3)cc1 +N#Cc1ccccc1OCC(O)CNCCNC(=O)Nc1ccc(Br)nc1 +CCCS(=O)(=O)Nc1ccc(F)c(Nc2ccc3nccnc3c2)c1Cl +COc1cc(N(CC2CC2)c2cccc3c(C(F)(F)F)cccc23)cnc1C(=O)C1CC1C(=O)O +CCNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(CCN(C)C)c3n2)cc1 +CC1CC(C)CN(C(=O)c2cc(Br)ccc2NC(=O)CCC(=O)N(C)C)C1 +CC(C(=O)O)c1ccc2c(c1)OCC(Cc1ccccc1)C2O +CC(C)(C)c1ccc(CNC(=O)NCc2ccc(NS(C)(=O)=O)c([N+](=O)[O-])c2)cc1 +O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 +COc1ccc(Cl)cc1N1CCN(C2CN3CCC2CC3)C1=O +O=C(Nc1ccccc1)N1CCC(Cc2cnc3ccccc3c2)CC1 +Cc1nc(N)nc(-c2cc(CN3CCN(S(C)(=O)=O)CC3)cnc2Nc2ccc3scnc3c2)n1 +O=C1CC(CN2CCC(C(=O)c3ccc(F)cc3)CC2)Cc2[nH]ncc21 +CN(C)CCc1cccc2c1ccn2S(=O)(=O)c1ccccc1 +CC(C)c1onc(-c2ccc(F)cc2)c1-c1ccncc1 +CCCC1(CCc2ccccc2)CC(=O)C(C(c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)C(C)(C)C)=C(O)O1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1nc(C(F)(F)F)c(C(=O)O)s1 +Cc1nnc2n1-c1ccccc1C(c1ccccc1)=NC2NC(=O)Nc1ccc(Cl)cc1 +CCCCCCCN(CCCCCSc1nc(-c2ccc(C)cc2)c(-c2ccc(C)cc2)[nH]1)C(=O)Nc1ccc(F)cc1F +COc1ccccc1-c1ccc(CC(NC(=O)C2(S(=O)(=O)c3ccc(C)cc3)CCCCC2)C(=O)O)cc1 +CC(=O)N1CCCC1Cn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(C(=O)CC(F)(F)F)CC1 +NC(CC(=O)NC(c1ccccc1)c1ccccc1)C(=O)N1Cc2ccccc2C1 +CNC(=O)c1cc(OC)cc(N(CCCN2CCCC2)c2ccc3ncc(-c4cnn(CCO)c4)nc3c2)c1 +CCOC(=O)C1Nc2cc(Cl)cc(Cl)c2S(=O)(=O)N1Cc1cccc([N+](=O)[O-])c1 +Oc1c2c(nc3ccccc13)C(c1ccc3c(c1)OCO3)N(c1ncccn1)C2 +Cn1ccc(CNC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)n1 +Clc1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1Cl +CC(NP(=O)(OCC1C=CC(n2cnc3c(N)ncnc32)C1)Oc1ccccc1)C(=O)OCC(C)(C)C +CC(=O)Nc1cc(-c2cccc(C)c2)nc(-n2nc(C)cc2C)n1 +CN(Cc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)CC1CCCN1C +COc1cc(-c2cccn(Cc3ccc(CCC(=O)O)cc3)c2=O)ccc1NC(=O)Nc1c(C)cccc1C +COc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3)CCC2C(=O)NO)cc1 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3ccco3)nc21 +CCC(=C(c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccc(O)cc1 +O=P([O-])(O)C(O)(C[n+]1cccc(Cc2ccccc2)c1)P(=O)(O)O +Cc1c(CO)nc(O)c2c1ccc1nc(Nc3c(Cl)cccc3Cl)n(C)c12 +Cc1ccc(-c2ncc(C(=O)NCCCN(C)c3ccccc3)nc2-c2ccc(C)cc2)cc1 +CCCC(Cc1cc2cc(-c3ccccc3C)ccc2nc1N)C(=O)NCC1CCCCC1 +O=C(NNc1ccccn1)C12CC3CC(CC(C3)C1)C2 +NS(=O)(=O)c1cc(NC(=O)Nn2ccc3ccccc32)c(Cl)cc1Cl +CC(=O)OC1CC2CCC3C(CCC4(C)C3CC([N+]3(C)CCCCC3)C4OC(C)=O)C2(C)CC1N1CCCCC1 +CN1CCCC(c2nc3ccccc3n2Cc2ccc(F)cc2)C1 +Cc1c(Cc2ccc(S(C)(=O)=O)cc2)c2c(n1CC(=O)O)CCNC2=O +Cc1ncn(-c2ccc3c(c2)CCc2cn(Cc4ccccc4)nc2N3)n1 +O=C(NC(c1ccc(F)cc1)c1ccnc(F)c1)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1 +NC1C2CN(c3ncc(C(=O)Nc4ccc(OC(F)(F)Cl)cc4)cc3-c3cncnc3)CC12 +CCCCc1nn2c(-c3ccccc3)c(C)nc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1ccccc1S(=O)(=O)c1c(C(=O)NNCCO)[nH]c2ccc(Cl)cc12 +Cn1c2c(c3cc(S(=O)(=O)c4cccc(F)c4)cc(O)c31)C1CCC(C2)N1 +CC1CN(C(C)CO)S(=O)(=O)c2ccc(C#Cc3cccnc3)cc2OC1CN(C)C(=S)NC1CCCCC1 +CN(C)CCCOc1cc(F)c(-c2c(Cl)nc(-n3ccnc3)nc2NCC(F)(F)F)c(F)c1 +CNc1nc(Nc2ccc3c(c2OC)CN(C(C)(C)O)C3=O)ncc1C(F)(F)F +O=C(NC1CCCC1NC(=O)c1ccc2c(c1)N=CC2Cl)c1ccc(-n2ccccc2=O)cc1 +CN1CCCCC(c2ccc(C#Cc3ccc(F)cc3)cn2)C1=O +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(Cl)cc2)o1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(OCC4CCC4)cc3)C2)cc1 +CN1CCN(CCCN(C(=O)Nc2ccc(F)c(Cl)c2)C2CCC3(c4cccc(C#N)c4)CC3C2)CC1 +C=CC(=O)N(C)c1cccc(-n2c(-c3nc(-c4cnn(C5CCN(C)CC5)c4)cnc3N)nc3ccccc32)c1 +O=C(NCC1(O)CCCCC1)c1cc(OCC2CC2)c(Cl)cn1 +COC1CCC2(CC1)Cc1ccc(OCC(C)C)cc1C21N=C(N)N(CC(F)(F)F)C1=O +CNC(=O)c1cn(C)c2c1C(C)(C)Cc1cnc(Nc3cccc(OC4CCN(C)CC4)c3)nc1-2 +NC(=O)c1c(-c2ccc(Cl)cc2Cl)csc1NC(=O)Cc1ccccc1 +C=CCNc1nc(N2CCC(NCC(c3ccccc3)(c3ccccc3)c3ccccc3)CC2)nc2c1ncn2CC=C +N=C(N)c1ccc(CNC(=O)CNC(=O)C(CCc2cccc[n+]2[O-])NS(=O)(=O)Cc2ccccc2)cc1 +CCC(=O)Nc1ccc(Sc2nc(Nc3cc(C)[nH]n3)c3ccccc3n2)cc1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)C1CCN(C)CC1 +O=C1c2c(F)cc(C3CC3)cc2OCCN1c1nccc(-c2ccnc3[nH]c(C4=CCNCC4)cc23)c1CO +Cc1csc(NC(=O)NC2C3CC4CC(C3)CC2C4)n1 +O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)C1CCOC1 +CS(=O)(=O)c1ccc(-c2nnc(C=Cc3nnc(-c4ccc(C#N)cc4)o3)n2-c2ccccc2Cl)nc1 +N#CC(c1cccnc1)N1CCN(C(=O)CN(Cc2ccccc2)Cc2ccccc2)CC1 +CC(Nc1cc(-c2c(N)nn3cccnc23)ncn1)c1ccccc1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccsc2S(=O)(=O)NC(=O)c2ccccc2)cc1 +O=C(c1ccc(C(F)(F)F)cc1)C(O)c1ccc(C(F)(F)F)cc1 +CC1(C)c2cc(N3CCC(O)CC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +C1=CCNc2cc[n+](c3ccccc23)CCCCC[n+]2ccc(c3ccccc32)NC1 +CC1CN(C(C)C)C(=O)c2cccc(NC(=O)c3ccncc3)c2OC1CN(C)Cc1ccccc1Cl +COC(=O)C1=C(c2ccc(-c3ccco3)cc2)CC2CCC1O2 +CC1CC(c2ccncc2NC(=O)c2nc(-c3c(F)cccc3F)ccc2N)CC(N)C1O +COc1cc(C=CC(=O)NC2CCC(NC(=O)C(O)C(N)CCc3ccccc3)CC2)cc(OC)c1OC +COc1cc2c(c3c1c(=O)c1c4ccc(Br)cc4ccc1n3C)C(OC(C)=O)C(OC(C)=O)C(C)(C)O2 +CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccc(Cl)cc1n2CCOCCF +Cc1cc(-c2n[nH]c3ccc(C(=O)NC(CO)c4cccc(Cl)c4)cc23)ccn1 +O=C(NCCCCN1CCN(c2ncccn2)CC1)c1cc2ccccc2cn1 +O=C(NCCC1CCN(Cc2ccccc2)CC1)c1cccc(-c2n[nH]c3ccc(-c4nc[nH]n4)cc23)c1 +O=C(CCc1ccccc1)NC(Cc1ccccc1)C(=O)CCl +CCOc1ccc(N=c2[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +FC(F)(F)c1ccc(Nc2nc(N3CCCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1Cl +CN(C(=O)c1ccccc1-c1ccccc1)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCCC(O)C1CC(Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(C(C)=O)c1 +CC(C)n1nc(-c2cc(F)c3cn[nH]c3c2)c2c(N)ncnc21 +O=C(NCCCn1ccnc1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1OCCc3ccccc31)CC2 +Clc1cc(Cl)c2c(c1)oc1c(Cl)c(Cl)c(Cl)cc12 +O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccc(F)cc3F)CCC2)c1 +Cc1oc(-c2ccccc2)nc1CCOc1cccc(Cc2nn(-c3ccccc3)nc2C(=O)O)c1 +COc1cnc(C(=O)Nc2cc(C)c(F)c(C3(CF)CC(C(F)(F)F)OC(N)=N3)c2)cn1 +CN(Cc1c[nH]c2nc(N)nc(N)c12)c1cccc2ccccc12 +NC(CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)C(=O)C1)C(=O)N1Cc2ccccc2C1 +Cc1ccc(-n2ccnc2)c(NC(=O)c2cnc(-c3ccccc3)s2)c1 +COc1ccc(CCNc2cc(N3CCN(C(=O)c4ccccc4F)CC3)ccc2[N+](=O)[O-])cc1OC +Cn1nc(N)c2cn(C3OC(CO)C(O)C3O)c3ncnc1c23 +O=Cc1cccc(-c2ccc(C3(NCC(=O)Nc4ccc(F)c(Cl)c4)CCN(C4CCCC4)CC3)cc2)c1 +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(n1cc(CCC(=O)OCc3ccccc3)nn1)CC2 +Cc1cc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)no1 +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(OC(=O)Nc3ccccc3)CCc3ccccc32)c1 +CCCn1c(=O)c2[nH]c3cnccc3c2n(CCC)c1=O +Cn1cc2c(nc(NC(=O)Nc3ccc(Cl)cc3)n3nc(-c4ccco4)nc23)n1 +CC(CCc1c[nH]c2ccc(F)cc12)N(CC1CC1)C1COc2c(F)ccc(C(N)=O)c2C1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)CNCCO2 +CC1Oc2ccc(CN3CCC(c4ccccc4)CC3)cc2NC1=O +CCCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(F)c4)c3)nc2n(CC)c1=O +Cc1cccnc1C(F)(F)CNc1ccc(C#N)c(CC(=O)NCCONC(=N)N)c1F +Cc1nnc2n1-c1ccc(-c3cncc(C(F)(F)F)c3)cc1CC2 +Cc1ccncc1-c1cc2c[n+]([O-])c(NC(=O)C3CC3F)cc2cn1 +CCC(Nc1ncc(-c2ccccc2)n1C)c1ccc(Cl)cc1 +N=C(N)c1cccc(OC(C(=O)Nc2ccc(-n3ccc(C(F)(F)F)n3)cc2)c2ccccc2)c1 +COc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Sc2ccc(C(C)C)cc2)CC1 +Nc1[nH]cnc2c(C3NC(CSCc4ccccc4)C(O)C3O)cnc1-2 +CC(Nc1ncc(F)c(N2CCOC2=O)n1)c1cc(F)c(Br)cc1F +COc1ccc2nc(COc3cc4c(cc3Cl)OCO4)[nH]c2c1 +CCc1c(C)[nH]c(=O)c(NC)c1Cc1cc(C)cc(C)c1 +CCc1nccc2c1c(Sc1ccc(Cl)c(Cl)c1)c1n2CCC1CC(=O)O +CNC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)C(CSCC(=NO)c1ccc(-c2ccccc2)cc1)C(=O)NO +O=C(O)C1CN(Cc2ccc(-c3cc4cc(OCC5CC5)ccc4o3)c(F)c2)C1 +CNc1cc(CSc2ncccc2C(=O)Nc2cc(C)cc(C)c2)ccn1 +CC1COCCN1c1nc(N2CCCC(CO)C2)nc2nc(-c3cccc(C(N)=O)c3)ccc12 +O=C(CN1CCCCC1)NN1c2ccccc2Sc2cc(Cl)ccc21 +CC(C)C(Oc1ccc(CNC(=O)C2CCCN2C(=O)C(N)C2CCCCC2)cc1)C(=O)O +COc1ccc(C2C3=C(CC(C)(C)CC3=O)Nc3nc4c(c(N)c32)CCCC4)cc1 +CC1Cc2cc(CCN3CCN(CCc4ccc5c(c4)CC(C)OC5=O)CC3)ccc2C(=O)O1 +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)c2cccc3c2cnn3CCCNc2ncc[nH]2)C(=O)O)c(C)c1 +O=S(=O)(c1ccc(OC2CCCC2)c(F)c1)N1CCCC(Cn2ccnc2)C1 +Cn1c(=O)c2c(-c3cc(F)ccc3Br)c(CN)c(O)nc2n(C)c1=O +Cc1c(-c2ccc(F)c(C(F)(F)F)c2)sc2c1c(=O)n(CCCO)c(=O)n2C +CC#CCNc1ccc(S(=O)(=O)N2CCC(S)C2)cc1 +CC(C)(O)CCc1ccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)cc1 +CCOC(=O)N1CCN(CCCOc2ccc(-c3cc[nH]c3)cc2)CC1 +Cn1cc(C2=C(c3nn(CCCN4CCCCC4)c4ncccc34)C(=O)NC2=O)c2ccccc21 +COc1cc2[nH]c(C)c(C3CCCCC3)c(=O)c2cc1Cl +CNc1nc(CC(F)(F)F)c(-c2ccnc(Nc3ccc(O)cc3)n2)s1 +CN1Cc2n[nH]c(=O)c3cccc4[nH]c(c2c43)C1 +O=C1c2cc3c(cc2-c2c1c1ccc([N+](=O)[O-])cc1c(=O)n2CCCN1CCCC1)OCO3 +Cc1cccc(C(=O)C2=C(N(C)C)C(=O)NC3(CCCC3)C23CCCC3)c1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cnn(CC4CCCCO4)c3)c(C(=O)O)n1)CC2 +COc1ccc2c(c1)CN(C)CC2c1ccc(C)c(F)c1 +O=C(NS(=O)(=O)c1ccc(Cl)cc1)c1ccc(Br)cc1Cl +CCOc1cc(C=NN=C(N)CC(O)c2cccc3ccccc23)ccc1O +COc1cc2c(Oc3ccc(Nc4ccc(C(C)(C)C)cc4)cc3)ccnc2cc1OCC(O)CN1CCOCC1 +CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)N3CCC(c4cccc(C(F)(F)F)c4)CC3)sc12 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN(C)C(C)(C)C)C1=O)c1ccccc1 +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)Nc1cccc(F)c1 +CCN(CC)c1ccc(NC(=O)c2c(-c3c(Cl)cccc3Cl)noc2CCC2CCOCC2)cc1 +Cc1ncc(-c2ccn(C)c(=O)c2)c(OCC2CC2c2ccccn2)n1 +Cn1cc(Cc2cn(CC(=O)N3CCN(Cc4ccccc4)C(=O)C3)c(SCc3ccc(F)cc3)nc2=O)cn1 +CCCc1c(Oc2c(C)n(-c3noc4cc(Cl)ccc34)c3ccc(OC(F)(F)F)cc23)cccc1OC(C)C(=O)O +COc1ccc(CCCOC(=O)C2CCCCN2S(=O)(=O)c2ccccc2)cc1OC +Cc1cn(C2C=CC(COP(=O)(OCC(Cl)(Cl)Cl)OCC(Cl)(Cl)Cl)O2)c(=O)[nH]c1=O +CC(C)N1CCN(C(=O)OC2CCN(c3nnc(N4CCOCC4)s3)CC2)CC1 +O=C(O)CCNCc1cc([N+](=O)[O-])cc2nc(O)c(O)nc12 +CCN(CCCCNC1=CC(=O)C(NCCCCN(CC)Cc2ccccc2OC)=CC1=O)Cc1ccccc1OC +Cc1cccc(Cn2c(C)nnc2C2CCN(c3ccccn3)CC2)c1 +N#Cc1cccc(-c2coc(-c3ccc(Oc4ccc(N5CCCC56C(=O)NC(=O)NC6=O)cn4)cc3)n2)c1 +CCOc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(C#N)cnc2cc1OCCCN1CCN(C)CC1 +O=c1ncn(Cc2ccc(F)cc2F)c2ccc(Oc3ncccc3Br)cc12 +CN(C)CC(NC(=O)c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1)c1ccccc1 +CCc1ccc(Oc2ccc(S(=O)(=O)NCCc3ccccn3)cc2F)c(O)c1 +CC(C)(C)[Si](OCc1cnn(Cc2ccccc2)c(=O)c1)(c1ccccc1)c1ccccc1 +CCN1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O +c1ccc(-n2cnc3ccc(OCc4ccc5ccccc5n4)nc32)cc1 +CCCCCS(=O)(=O)NC(=O)CCc1ccccc1Oc1ncc(C(F)(F)F)cc1Cl +COCCCN(C)c1ncc(Cl)c(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)n1 +O=C(O)COc1ccc(C(=O)CNC(=O)c2sc3c(c2Cc2ccccc2)CNCC3)cc1OCC(=O)O +CC(C)c1cc(Oc2c(Br)cc(NC(=O)C(N)=O)cc2Br)ccc1O +CCNc1nc(N=[N+]=[N-])nc2c1ncn2C1C(O)C(O)C2(C(=O)NC)CC12 +Nc1nc(NC2CCS(=O)(=O)CC2)c2sc(-c3ccc(C(F)(F)F)cc3)cc2n1 +CCn1c(-c2ccccc2-c2cccc(NCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 +CC(C)Nc1nc2ccc(-c3ccnn3-c3ccc(F)cc3)cc2s1 +COCCn1c(C)c(-c2cnc(C)nc2OCC2CC2c2ccc(C)cn2)ccc1=O +CC(=NO)c1cccc(C(C)(C)NC(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)c1 +COc1cc2c(cc1F)C1(CO2)C(=O)N(Cc2ccc(C(F)(F)F)o2)c2ccccc21 +COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCC(=O)NO +COc1ccc(C)cc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CCn1c(C)c(-c2ccc(CC(NC(=O)c3c(C)cccc3Cl)C(=O)O)cc2)c(=O)n(CC)c1=O +O=C(CCNCCN1CCCCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 +CC1CN(C(=O)c2cn3c4c(cccc24)OCC3C2CCCCC2)CC(C)N1C +NC(CC(=O)N1CCCC1C(=O)NCCCCc1nn[nH]n1)Cc1ccccc1F +N#Cc1ccc(C2=NOC3CCCCCCC23)cc1C(F)(F)F +CC(C)(Oc1ccc(N2CCOCC2)cn1)C(=O)NC1C2CC3CC1CC(CC(N)=O)(C3)C2 +O=c1c2cn[nH]c2c2ccc(-c3cncnc3C3CCCC3)cc2n1CC(F)(F)F +O=c1c2cc(F)ccc2nc(CNc2ccccc2F)n1-c1ccccc1Cl +CC(C)OC(=O)N1CCN(c2ccnc(-n3ccnc3)n2)C(CC(=O)NCc2ccc3c(c2)OCO3)C1 +CC(C)c1cc(-c2ccccc2)nc(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +CCc1c(C#N)c(-c2ccc(-c3ccccc3SC)cc2)c(C(=O)O)n1C +CCCCCCS(=O)(=O)c1ccc(C(=O)CCN2CCNC(=O)C2)c(Cl)c1 +NCCOc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F +O=C(O)CC(NC(=O)c1cccc(Cl)n1)c1ccc(-c2ccccc2)cc1 +CCCCC(NC(=O)OC1CN(C(=O)c2ccc(-c3ccccc3)cc2)CC1(C)C)C(=O)C(=O)NC(C)c1ccccc1 +N#Cc1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CC3C3CC43)c(F)c2)s1 +CC(C)(CNC(=O)c1cnc2ccccc2n1)c1ccccn1 +CN1CCC(=CCn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +COc1cc(-c2nn(C3CCC(N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2[nH]1 +COC(=O)CCCC#Cc1ccc(CC(NC(=O)c2ccc(S(N)(=O)=O)cc2)C(=O)O)cc1 +Cc1ccc(S(=O)(=O)C2(C(=O)NC(Cc3ccc(-c4ccccc4)cc3)C(=O)O)CCCCC2)cc1 +CCNC(=O)c1ccc(-c2nnc(C3(c4ccc(Cl)cc4)CCC3)n2C)cc1 +COc1cccc(NCCC2(c3ccc(F)cc3)CCOC(C)(C)C2)c1 +COCC1CCCN1C(=O)c1cn2c(n1)CN(c1cc(-c3ncc(C)cc3C)c(Cl)cn1)CC2 +CCS(=O)(=O)Nc1cccc2c1CCCC2c1c[nH]cn1 +COc1cc(Nc2nc3c(s2)CCCC3c2ccccc2)ccc1-c1nc(C)no1 +CCN(CCCN1CCc2cc(OC)ccc2C1)S(=O)(=O)c1ccc(C)cc1 +O=[N+]([O-])c1ccc(C=Nn2c(CO)nc3ccccc32)s1 +CC(Cc1ccc(OCC(N)=O)cc1)NCC(O)c1cccc(Cl)c1 +COc1ccc2c(c1)CCC1N=C(NCC3CCC(CNS(=O)(=O)c4ccccc4F)CC3)CC21 +Cc1cc(-n2[nH]c3c(cnc4ccccc43)c2=O)c(Cl)s1 +CC(C)(C)NC1CCC(n2cc(C(N)=O)c(Nc3ccc(C(F)(F)F)cc3)n2)C(C#N)C1 +CC(CCCc1ccccc1)NC(=O)Nc1ccc2ncc(-c3cnn(C)c3)nc2n1 +CC=CC(C(=O)NCCCC)N1C(=O)c2cc(NC(C)=O)ccc2NC(=O)C1C +O=c1[nH]c2cc([N+](=O)[O-])ccc2oc1=O +NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CCc1cc(-c2ccc(-c3cccc(Cl)c3)cc2)no1 +CC1SCc2ncnc(N3CCN(C(=O)C(Cc4ccc(Cl)c(F)c4)CC4(N)CC4)CC3)c21 +Cc1ncccc1NC(=O)c1cccc(-n2cc(NC(=O)Nc3ccccc3Cl)cn2)c1 +O=C(NC1CCN(Cc2ccc(OC3CCNCC3)c(Br)c2)CC1)c1cc2cc([N+](=O)[O-])ccc2s1 +CCCCCC#CCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +CC1CC(N)CC(c2ccncc2NC(=O)c2cccc(-c3c(F)cccc3F)n2)C1 +c1cc(-c2csc3ncnc(N4CCC(COCCN5CCCC5)CC4)c23)ccn1 +CC(C)(C)OC(=O)N1CCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)C1 +COc1ccc(Oc2ccc3cc4n(c(=O)c3c2)C(=S)NC4=O)cc1 +NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(F)cc3)c2)c1 +N#CC(=Cc1cn(CC(=O)O)c2ccccc12)C(=O)N1CCCc2ccccc21 +CC(CO)n1cc(C(=O)c2cc(NC(=O)Cc3cccc(C(F)(F)F)c3)ccn2)c2cnccc21 +Cc1sc2nc(CSC(C)C(=O)Nc3ccc(Cl)cn3)nc(O)c2c1C +CC(C)c1ccc(Cn2cc(C=NNC(=O)c3ccc(O)c(Cl)c3)c3ccccc32)cc1 +COc1cn(-c2ccc3c(c2F)C2(CCC2)C(=O)N3C)nc(-c2ccnn2-c2ccccc2)c1=O +CN1C(=O)CC(c2ccccc2F)C1C(O)c1ccc(-c2ccccc2)s1 +CC1(C)CC2CC(C)(CN2C(=O)c2ccc(-c3csc4ccccc34)cc2Cl)C1 +O=C1Nc2cc(F)ccc2C1CCCCN1CCN(c2ccccn2)CC1 +CN(C)CCCCN(CC1Cc2ccccc2CN1)C1CCCc2cccnc21 +O=C(c1cccc(-c2cccc(O)c2)n1)c1cccc(O)c1O +COc1cc2ncc(C#N)c(Nc3ccc(Cc4ccccc4)cc3)c2cc1OC +O=C(O)CN1CC(c2nc3ccccc3n2C2CC3CCCC(C2)N3C2CC3CCCCC(C3)C2)C1 +COc1ccc(CCc2cccc3c(=O)c4ccccc4[nH]c23)cc1 +CNC(=O)Nc1nc2cc(Oc3cccc(C#N)c3)ccc2[nH]1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccc(F)cc3)s2)C(C)O)c(C)c1Cl +COC(=O)Nc1ccc2c(-c3c(-c4ccccn4)nn4c3CCC4)ccnc2c1 +Nc1nc2c(ncn2CCN(CCP(=O)(O)O)CCP(=O)(O)O)c(=O)[nH]1 +Nc1cccc(C(=O)n2nc(C(=O)OCC(F)(F)F)c3ccccc32)c1 +Cc1cc(Nc2nc(N3CCN(C(=O)c4ccccc4Br)CC3)nn3cccc23)n[nH]1 +Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(N3CCC(N(C)C)C3)nc12 +COc1ccc2c(c1)OCc1c-2ccc2c1C(C)=CC(C)(C)N2 +CCCCC1(CC)CS(=O)(=O)c2cc(OCCCP(=O)(O)O)c(OC)cc2C(c2ccccc2)N1 +O=C(NCc1ccccc1)c1cccc(Nc2c(O)c(=O)c2=Nc2ccccc2)c1O +CN(CC1CNc2nc(N)nc(O)c2C1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +CN(CCCCCc1ccccc1)CCCCN1CCN(CCCCCCCCCOc2ccccc2)CC1 +C=C(CCC(C)C1CCC2(C)C3CCC4C(C)C(O)CCC45CC35CCC12C)C(C)C +COP(=O)(c1ccccc1)c1c(C(N)=O)[nH]c2ccc(Cl)cc12 +COc1cc(S(=O)(=O)c2cc(F)cc(F)c2)cc2c3c(oc12)CCNC3 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+CC(C)CC(=O)N(Cc1ccccc1-c1ccccc1)C1CCNC1 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(OC(C)C)c1 +CC1(COc2ccc(-c3ccc(F)cc3)cc2)Cn2cc([N+](=O)[O-])nc2O1 +CCc1cc2cc(NS(=O)(=O)c3ccc(C#N)cc3OC)ccc2n(CC)c1=O +CN(C)C=Nc1nsc2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12 +COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)n2)cc1 +COc1ccc(CCNC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)cc1Br +CC1OC(=O)C2CC3CC(C(=O)Nc4cccnc4)CCC3C(C=Cc3ccc(-c4cccc(C(F)(F)F)c4)cn3)C12 +O=C(NC1CCCCCC1)c1cc2cccnc2n(CCN2CCOCC2)c1=O +COCC(NC(=O)c1ccc(Cl)s1)C(=O)Nc1ccc(N2CCOCC2=O)c(C)c1 +COc1ccc(-c2c(-c3nc(C)n4ncnc(N5CCC5)c34)cnn2C)cc1 +O=C1N(CCN2Cc3ccccc3C2)CCN1c1cscc1-c1ccccn1 +CN1CCC(c2ccccc2)=C(C(=O)OCCc2ccc3c(c2)CCO3)C1 +O=C(NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21)c1ccco1 +CC1CN(C(=O)Cc2nc(N3CCOCC3)cc(=O)n2C)c2ccccc21 +O=C(Nc1ncnc2[nH]cnc12)c1cccc(-c2ccc(-c3c[nH]cn3)cc2)c1 +C=C(Br)C(=O)Nc1ccc(C(=O)C=Cc2cccc(OC)c2OC)cc1 +N#Cc1ccccc1OCC(O)CNCCNC(=O)Nc1ccc(OCCCF)cc1 +O=C1OC(c2ccc(F)cc2)CN1Cc1ccc(Cl)cc1Cl +CCCCCCCCCCCCCCC(O)C1CCC(C2CCC(C(C)O)O2)O1 +c1ccc2c(c1)CC(Nc1nc(Nc3ccncc3)nc(N3CCNCC3)n1)C2 +CC(C)(COc1cnc(-c2ccc(-c3ncc(C4(C(F)(F)F)CCC4)[nH]3)cc2)cn1)C(=O)O +CC(C)CC1C(=O)NC(C(=O)NCCc2ccccn2)CCCCNC(=O)OCCCC1C(=O)NO +Cn1c2c(c3cc(S(=O)(=O)c4cccc(OC(F)F)c4)ccc31)C1CCC(C2)N1 +CC1=C(C(=O)OCc2ccc3c(c2)OCO3)C(c2ccco2)N(C)C(=O)N1C +CN(C(=O)c1cc(-c2ccccn2)[nH]n1)c1ccc(OCB2C=Cc3ccccc3N2)cc1 +COCCOc1cc(CC2CCN(CCc3ccc4c(c3)C(O)CCO4)CC2)ccc1Br +O=C(NCC1(O)CCC(F)(F)CC1)c1cc(-c2ncc(F)cn2)ccc1Cl +N#Cc1ccc(Cn2cncc2CNC2Cc3ccccc3CN(Cc3cc(F)cc(F)c3)C2=O)cc1 +CC(NS(=O)(=O)c1ccccc1)C(=O)NC1=NN=C(c2ccc(Br)cc2)CS1 +Nc1nc(=O)n(C2CCC(NS(=O)(=O)c3cccc(-c4ccccc4Cl)c3)C2)cc1F +CC1=C(c2nc(-c3ccc(C#N)cc3)cs2)C(c2ccc(Cl)nc2)NC(=O)N1 +Cc1nc(Cl)ncc1C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=C1N(Cc2cccc3ccccc23)C(CCc2ccccc2)C(O)C(Cc2ccccc2)N1Cc1cccc2ccccc12 +C=Cc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12 +Cc1ccc(C(=O)NC(C)C)cc1C#Cc1cnc2ccnn2c1 +CNCCCN(C)Cc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2O)cc1 +CCOC1CN(CC(=O)Nc2ccc(-n3ccccc3=O)cc2F)CC1NC(=O)c1ccc(Cl)s1 +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1CCCC(=O)NCC(F)(F)F +CC(C)OCC(Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccccn1 +Cc1ncnc(C)c1-c1ccc(Oc2nccc3n[nH]cc23)cc1C#N +O=C(OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1)c1ccc(OCCCN2CCCCC2)cc1 +Cc1cc(-c2cccc3c2CCN2C(=O)CN=C(n4cnc(C5CC5)c4)C=C32)sn1 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cc(Cl)cc(C#N)c1 +CN1C(=O)C(c2ncc(C#Cc3ccccc3)cn2)C2CCCC21 +N#Cc1ccc(-c2ccc(CNCCNc3ccnc4cc(Cl)ccc34)s2)cc1 +CCC(NC(=O)c1cc(C(=O)NC(C)c2ccc(F)cc2)n2c1CSC2)c1ccccc1 +CCCN1CCc2cc(F)cc3c2C1Cc1ccc2c(c1-3)OCO2 +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2cccc(Br)c2)c(C)c1 +c1ccc(N2CCN(CCC3CCC(Nc4ncccn4)CC3)CC2)cc1 +O=C1NCc2ccc(OCCCN3CCN(c4cccc5c4COCC5)CC3)cc21 +CCNC(=O)C(=O)C(Cc1ccc(Cl)cc1)NC(=O)C(NC(=O)CCC1CCCS1)C(C)C +Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(C#N)c(Oc3ccc(F)cc3)c(Cl)c2c1 +CC(=O)N1CCC(C(=O)Nc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +Cc1nc2cc(-n3ncc(C(=O)c4cc5cc(CN6C(C)CCC6C)ccc5[nH]4)c3N)ccc2[nH]1 +Cc1cccc(C(=O)NC2(C(=O)O)Cc3ccc(F)cc3C2)c1CC(C)C +CNC(=O)C(C)(C)CNC(=O)C(CC(O)C(N)CC(Cc1ccc(OC)c(OCCCOC)c1)C(C)C)C(C)C +Cc1cc(Nc2nc(-c3cccc(C)n3)nc3ccccc23)ccn1 +O=C(O)CN1CCC(c2nc3ccccc3n2C2CC3CCCC(C2)N3C2CC3CCCCC(C3)C2)C1 +CC(=O)NC1C(NC(=N)N)C=C(C(=O)OCCCOC(=O)c2cc(N)ccc2O)OC1C(O)C(O)CO +O=C(CC(CCCCc1ccccc1)C(=O)NC(CC1CCCCC1)C(=O)NCCc1ccccc1)NO +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccnc1SCc1ccncc1 +COc1cc2c(c(Cl)c1Cl)C(=O)C(CCN(C)CC(=O)O)(c1ccc(F)cc1)C2=O +Cc1c(C(N)=O)sc2nc(-c3ccncc3)nc(NCC(N)Cc3ccccc3)c12 +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(Nc2ccc3oc(C(=O)NCCN4CCCC4)cc3c2)n1 +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccncc1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCC3)CC2)c1)c1cccc(C(F)(F)F)n1 +O=C1CN(CC(=O)NC2CCN(Cc3ccccc3)CC2)C(=O)c2cc(Oc3ccccc3)ccc2N1 +CC(C)(CNC(=O)NCC(F)(F)F)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1 +Nc1cccc(-c2cc(O)c3cc4c(cc3n2)OCO4)c1 +COc1ccc(-c2cn(-c3ccc(C(=O)O)c(O)c3)cc2C#N)cc1F +COc1ccc2c(Cc3ccccc3)c(-c3ccc(Cl)cc3)c(=O)oc2c1 +CNC(=O)N(C)CCC#Cc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +CC(C)CN(C(=O)C(C)C)c1cccc(C(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)c1 +N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 +CCCCC1=NC(C)(C2CCCC2)C(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC2CCN(C(=O)N3CCN(C)CC3)CC2)c2ccccc12 +O=C(NC1CCC(c2ccc(-c3nc4[nH]c(OC5COC6C(O)COC56)nc4cc3Cl)cc2)CC1)OC1CCCC1 +CCCN1CCN(c2c(-c3ccncc3)c(-c3ccc(F)cc3)c(C(=O)OC)n2C)CC1 +CNC(=O)C(CC(C)(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CCOCC2)n1 +Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2cc(-c3cn(CCO)nn3)ccn12 +Cc1ccc(N2CCc3ncnc(NCc4cccc(C#N)c4)c3C2)c(C#N)c1 +Cn1cc(-c2cc(-c3ccc(N)nc3)ccc2OCC2CC2)c2cc[nH]c2c1=O +CC(C)(C)c1cccc(OCc2cc(=O)[nH][nH]2)c1 +C=C(C)CN1C(=O)N(CC(=C)C)C(Cc2ccccc2)C(O)C(O)C1Cc1ccccc1 +CC1CCC2C(C)C(Oc3ccccc3)OC3OC4(C)CCC1C32OO4 +Cc1cc(NC(=O)C(=O)c2cn(Cc3ccc(Cl)cc3)c3ccccc23)on1 +CSc1nc(C)cc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)n1 +O=C1OC2(CCC(C(=O)Nc3ncc(-c4ccccc4)cn3)CC2)c2cccnc21 +Fc1ccc(-n2c3c(c4cc(F)ccc42)CN(CCc2ccccn2)CC3)cc1 +O=C(CN1CC=CCC(NC(=O)c2ccc3ccccc3c2)C1=O)NC1CC(=O)OC1O +CC1(C)CC(=O)c2cc(C#Cc3ccccc3)cnc2C1 +COc1ccc2c(c1)[n+]([O-])c(C#N)c(-c1ccc(F)cc1)[n+]2[O-] +O=C(NC1CC1)c1cnn2ccc(N3CCCC3c3cc(F)cc(OCC(O)CO)c3)nc12 +N=C(Nc1cccc(F)c1)NC12CC3CC(CC(C3)C1)C2 +COc1cc(C(=O)n2nc(Nc3cccc(C)c3)nc2N)cc(OC)c1OC +FC(F)(F)Oc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3)nc3[nH]cnc23)cc1 +COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 +CN1CC2CC1CN2c1cc(F)c(-c2ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn23)cc1F +CC1(C)OCC(=O)C2=C1N=C1COC(O)=C1C2c1ccc(F)c(Br)c1 +CCCCc1nc(Cl)c(CC(=O)OC)n1Cc1ccc(NC(=O)c2cccc(C)c2NS(=O)(=O)C(F)(F)F)cc1 +CC(C)c1ccc(CNC2CCCCC2NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)cc1 +O=C(NCc1ncco1)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1 +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2C2CC2)OCC3)cc1 +Cc1cc(NC(=O)Nc2cc(C(C)(C)C)nn2-c2cccc(C#N)c2)ccc1Oc1ccncc1 +CCSc1ccc(NC(=O)c2ccc(C(=N)N(C)C)cc2)c(C(=O)Nc2ccc(Cl)cn2)c1 +CCN(CC)CCOc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O 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+CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(C(C)(C)CN2CCOCC2)cn1 +COc1cc(-c2ccc(S(N)(=O)=O)cc2)cc(OC)c1OC +Cc1ccc(C(=O)N(C)CC23CCC4(O2)C2Cc5ccc(O)cc5C4(CCN2CC2CC2)C3)cc1 +Cc1cc(C(=O)O)nn1Cc1cc(Br)cc2sc(N3CC=CCC3)nc12 +Nc1ncc(-c2cn[nH]c2)cc1C(=O)Nc1ccncc1 +CCCCCOc1ccc2c(c1)C(=O)C(=O)C=C2c1ccccc1 +CC(C#N)=Cc1cc(C)c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)c(C)c1 +COc1ccc2[nH]nc(-c3cccc(S(N)(=O)=O)c3)c2c1 +CNC(=O)C12CC1C(n1cnc3c(NCc4cccc(C)c4)nc(Cl)nc31)C(O)C2O +CONC(=O)c1ccc(C)c(Nc2nc(N(C)CC(C)(C)C)nc(N3CCCN(C)CC3)n2)c1 +Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2ccc(-c3ccn(C)n3)cn12 +CCn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(NC3CCOCC3)nc21 +COc1cc(Oc2ncccn2)ccc1-c1cc2c(cc1F)ncc1ncn(C3(C)CCN(CCO)CC3)c12 +O=C(CN1CCN(c2ccccc2F)CC1)Nc1nnc(C(F)(F)F)s1 +Cc1cc(OCc2nc(-c3cnc(OC(C)C)nc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O +CCCS(=O)(=O)N(CCOc1ccc2c(c1)C(Cc1cccc(Cl)c1)C(N)CC2)C1CC1 +Cc1cc(O)c(C(=O)CCc2ccc3c(c2)OCCO3)c(OC2OC(CO)C(O)C(O)C2O)c1 +Cc1c(N2CCC(C(N)c3ccccc3)C2)c(F)cc2c(=O)n(N)c(=O)n(C3CC3)c12 +C=CCCN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +CNC(C)C(=O)NC(C(=O)NC1CCCN(CC(c2ccccc2)c2ccccc2)C1)C1CCCCC1 +CN(C)C(=S)NN=C(c1ccc(F)cc1)c1ccccn1 +COc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 +CC(C)(C)C(=O)CN1C(=O)C(NC(=O)Nc2cccc(N)c2)N=C(c2ccccn2)c2ccccc21 +CC(Nc1nc(N)nc(N)c1Cl)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1O +CCCCCCCCCCCCCCOC1C(OC)OC(CNC(=O)C2CCCN2)C(O)C1OCCCCCCCCCCCCCC +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(S(C)(=O)=O)CCO1 +C=COC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)CCNC(=O)OCc1ccccc1)C(C)C +CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2nc3cc(Cl)ccc3o2)CC1 +NC(=O)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 +O=C(O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2cc3ccccc3c(Br)n2)cc1 +CCN(CC)c1nc2ccc(C(O)(c3ccc(OC)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 +CN(CCCNc1c2c(nc3ccccc13)CCCC2)CCCNc1c2c(nc3cc(Cl)cc(Cl)c13)CCCC2 +CC(C)CC(NC(=O)C1OC1C(=O)O)C(=O)NCCCCNC(=N)N +Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ccc(-c3ccccc3)cc1)C(=O)N2c1cc(O)ccn1 +COc1cc(-c2nc3c(c(C4(S(C)(=O)=O)CCOCC4)n2)OCC2COCCN32)c2cc[nH]c2c1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCCCCCOc1ccc(CN3CCCCC3)cc1)C2 +O=C(CN1CCSCC(NC(=O)c2ccc3ccccc3c2)C1=O)NC1CC(=O)OC1O +COc1cc(C(=O)c2sc3c(OC)cccc3c2N)cc(OC)c1OC +OCC1(N2CCC(n3c(-c4ccc(F)c(Cl)c4)nc4ccccc43)CC2)CCCCC1 +CC(=O)N1CCC(CCOc2ccc(-c3cc4c(ncn4C)c(C#N)n3)cc2C(F)(F)F)CC1 +CC(=O)N1CCC(C(=O)Nc2cnc(Nc3ccc4nc(C)sc4c3)n(Cc3ccc(Cl)cc3)c2=O)CC1 +N=C(N)c1ccc(O)c(CN2CCC(NS(=O)(=O)c3cc4nc(Cl)ccc4s3)C2=O)c1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCCN(C)C2)n1 +CC(C)N=C1SC(=Cc2ccc(O)c(Cl)c2)C(=O)N1CCCCc1ccccc1 +CC(C)(C)C1CSC(c2ccc(C#CCCP(=O)(O)O)cc2)SC1 +Cn1c(-c2ccccc2)nc(-c2nc(C(=O)O)cs2)c1-c1ccccc1 +Cc1ccc(S(=O)(=O)N(CC(C)C)C(CCCCNC(=O)OC2c3ccccc3-c3ccccc32)C(=O)NN)cc1 +NC(=O)Nc1sc(C#Cc2cccc(O)c2)cc1C(N)=O +FC(F)(F)c1ccc(Nc2nc(SCc3ccccc3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +N#Cc1ccc2c(c1)CCN(CCC1CCC(NC(=O)c3ccnc4ccccc34)CC1)C2 +C=CC(=O)OCC1c2cc(OC)c(OC)cc2CC2C3c4cc(OC)c(OC)cc4CC(C(C#N)N12)N3C +O=C1N=C(O)SC1=Cc1ccc(OCCC2CCCCC2)c([N+](=O)[O-])c1 +CCCOC(=O)c1c(-c2ccccc2)nc(CC)c(C(=O)SCC)c1CC +COC(=O)NC1CCC(c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)CC1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(OCCO)cc(-c3ccccc3)n2)CC1 +COCCON=C(C)c1ccc2nnc(C(C)c3c(F)cc4ncccc4c3F)n2n1 +O=C(NCCN1CCCCC1)c1cn2c(ccc3sc4ccccc4c(=O)c32)n1 +COc1ccc2[nH]cc(CCCCN3CCN(c4cc(C)c(OC)c(C)c4)CC3)c2c1 +CCCC(CCC)C(=O)Nc1ccc(Oc2c(Cl)cc(CC(=O)O)cc2Cl)cc1Br +CCCCC(C)C1=C(c2ccccc2)C2(Nc3ccccc3)CCCC2C1 +CS(=O)(=O)N(c1ccc(-c2cnc3ccc4ccncc4c3c2)cc1)S(C)(=O)=O +CCCCCCCCNC(=O)Nc1ncnc2c1ncn2C1OC(C(=O)NCC)C(O)C1O +CC(C)CC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(N)=O +COc1cc(Sc2c(-c3ccccc3)[nH]c3cccc(Br)c23)cc(OC)c1OC +Cc1ccc(-c2ccc(Cn3c(CC(C)(C)C(=O)O)nc4cc(OCc5ccc6ccccc6n5)ccc43)cc2)cc1 +CC1CCCN1CCCOc1ccc(-c2ccc(=O)n(C)n2)cc1Cl +CCn1nc(C)c(-c2ccccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)c1C +CN(C)CCNC(=O)c1cccc2c1nc(-c1cccnc1)c1ccccc12 +CCCCN1CCCc2cc(Oc3ccc(C(N)=O)cn3)ccc2C1 +N=C(N)c1ccc(OCCCCCCCCCCCCOc2ccc(C(=N)N)cc2)cc1 +O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OC2CCC3(CCCCC3)CC2)cc1F +CC(C(=O)Nc1cc(C2CC2)[nH]n1)c1ccc(N2CCCCC2=O)cc1 +COc1ccc(C=C2SC(N3CCN(C)CC3)=NC2=O)cc1OC +Cn1cc(-c2cnc3nnc(C(F)(F)c4ccc5ncccc5c4)n3n2)cn1 +CCOc1cc(F)c(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 +N=C(N)Nc1ccc(C(=O)Oc2ccc(CCN(CC(=O)O)C(=O)Cc3cccc(C(=O)O)c3)c(Cl)c2)cc1 +COc1ccc(CCNCCOc2cc(F)cc3c2OCCC3=O)cc1 +O=C(O)c1ccnc(-c2ccc3c(Nc4ccc(C(F)(F)F)cn4)ccnc3n2)c1C(F)(F)F +CSc1nc2nc3c(c(O)n2n1)CN(Cc1ccccc1)CC3 +NC(CC(=O)N1CCNCC1Cc1ccccc1)Cc1cc(F)c(F)cc1F +CC(C)S(=O)(=O)c1ccc(-c2ccc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1 +NC1CCC(CNC(=O)C2CCCN2C(=O)CC(c2ccccc2)c2ccccc2)CC1 +Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)c4cc[nH]c4)C3C3CCCCC3)cc2)no1 +C=CC(=O)Nc1cccc(-c2c[nH]c3nccc(-c4[nH]c(CCCO)nc4C(F)(F)F)c23)c1 +CC(C(=O)Nc1ccc(CCCC(=O)O)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 +O=C(NCCCCN1CCN(c2cccc(F)c2)CC1)c1cc2ccccc2cn1 +COc1ccc(COc2cccc3oc(-c4cn5nc(SC)sc5n4)nc23)cc1 +CSCOc1cc(Cl)cc(Cl)c1C=CC1CC(O)CC(=O)O1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)(C)C)n1)C(C)(C)CN2 +COc1cccc(-c2ccc(C(=O)N(C)Cc3ccccc3)s2)c1 +c1ccc2oc(SCCCCN3CCN(C4CCCCC4)CC3)nc2c1 +CNC(=O)Oc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +CC(=O)NCCCc1cccc2c1CC(CCCCc1ccccc1)O2 +CCCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 +CCC(C)C1CNC(=O)c2cc3cnc(Nc4ccc(N5CCN(C)CC5)cn4)nc3n21 +CC(C)n1nc(C#Cc2ccc(F)cc2)c2c(N)ncnc21 +CC(C)CCn1cc2c(nc(NC(=O)Cc3c(Cl)cccc3Cl)n3nc(-c4ccco4)nc23)n1 +O=C1N(c2cc(F)c3ccsc3c2)CCN1c1cnccc1C1CC1 +N=C(N)N1CCCC(NC(=O)CNC(=O)C(CCNC(=O)c2nccc3ccccc23)NC(=O)OCc2ccccc2)C1O +COc1cc(C(=O)NCc2cccc(C#N)c2)ccc1-c1cn[nH]c1 +COc1ccccc1-c1ccc2c(c1)C(C(C)OCCc1ccccc1Cl)=CC(C)(C)N2 +CC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCN1CCOCC1)c1ccccc1 +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1C1CCOC1 +CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCCCc3ccccc3)cc2C1=[N+](C)[O-] +NC(=O)c1ccc(Oc2ccc3c(c2)CCN(CCc2ccccc2)C3)nc1 +CC(C)CC(NC(=O)C(N)Cc1cccc2ccccc12)B(O)O +Clc1ccc2c(c1)C(N1CCN(CCc3ccccc3)CC1)=Nc1cccnc1N2 +CCCCCCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC +CN1CCN(Cc2cc(Nc3cc(-c4ccc(F)cc4)nc4ccccc34)cc(CN3CCN(C)CC3)c2O)CC1 +Cc1ncoc1C(=O)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +CC(C)(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(-c2ccccc2CO)cc1F +O=C(NCc1ccc(F)c(Cl)c1)c1cc2cccc(O)c2n(O)c1=O +CN(C1CCc2c(CC(=O)O)c3ccc(-c4ccc(F)cc4)nc3n2C1)S(=O)(=O)c1ccc(F)cc1 +Cc1cc(Cl)ccc1Oc1c[nH]c(COc2ccccc2)cc1=O +CN(C)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)cc1F +C=CC(=O)Nc1c(C)cccc1Nc1cc(N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)ncn1 +COC(=O)Nc1cccc(Cn2nc(-c3cc(F)cc(F)c3)ccc2=O)c1 +CCCN(CCO)c1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CC1(C)CC(=O)C2=C(C1)Nc1c(O)cccc1N(C(=O)c1cccc(Cl)n1)C2c1ccc(OCc2ccccc2)cc1F +O=C(O)c1cccc(NC(=S)NN=Cc2ccccc2OCc2ccc(Br)cc2)c1 +CC(C)(C)C(=O)Oc1ccc(C(=O)c2ccc(OC(=O)C(C)(C)C)cc2)cc1 +CC(CSC(CCc1ccccc1C(=O)N(C)CO)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O +c1csc(C2(c3cccs3)CC3c4ccccc4C2c2cccc[n+]23)c1 +CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(OC)c1CCC(=O)O +Cc1c(C(=O)NC(C)(C)c2cn3cccnc3n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +N#Cc1c[nH]c(C(=O)Nc2ccc(CCO)cc2C2=CCCCC2)n1 +CN(C)c1ccc2c(c1)CCN(c1cccc(-c3cc(Nc4ccc(N5CCOCC5)cn4)c(=O)n(C)c3)c1CO)C2=O +CCCCn1nc(C)c(C(=O)OC)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(S)=NCCc1ccccc1 +c1ccc2c(c1)c(NCCCCN1CCCCC1)cc1c3ccccc3c(NCCCCN3CCCCC3)cc21 +Cc1c(C2CN3CCN(C(=O)Nc4ccc(-n5cnnn5)nc4)CC3CO2)ccc(F)c1C#N +CNC(=O)c1ccccc1Nc1nc(Nc2ccccc2OC)nc2c1CCN2 +COc1ccc(NC(=O)c2ccc(C)c(Nc3ncnc4cnc(N5CCCC5)cc34)c2)cc1C(F)(F)F +CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccc4)c(Cl)c3)c2cc1NC(=O)C=CCN1CCC(O)CC1 +Cc1ccc(CNC(=O)N2CCC(NC(=O)Nc3nc4nn(C)cc4c4nc(-c5ccco5)nn34)CC2)cc1 +O=C(NCC1(O)CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1)Nc1c(Cl)cccc1Cl +c1cnc(NC2CCC(CCN3CCN(c4ccncc4)CC3)CC2)nc1 +O=C(O)c1cc(Br)cc2c(=O)cc(-c3ccc(OCc4ccc5ccccc5n4)cc3)oc12 +Cc1cc(C(=O)NCc2cc(Cl)ccc2-n2cnnn2)cc(-c2c[n+]([O-])ccc2C(C)C)c1 +Cc1nc(N2C(=O)CSC2c2c(F)cccc2F)sc1C +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCCC(O)C2)C1 +O=C(O)C(O)=CC(=O)C1(Cc2ccc(Cl)cc2)CCN(CC2CCCCC2)CC1 +Cn1c(=O)c(-c2c(Cl)ccc(C(=O)O)c2Cl)cc2cnc(Nc3ccccc3)nc21 +COc1ccc(-c2[nH]cnc2-c2cc(OC)c(OC)c(OC)c2)cc1F +c1ccc(OCC2CN(CCN3CCc4ccccc43)CCO2)cc1 +CC(C)C(CN1CCC(C)(c2cccc(O)c2)C(C)C1)NC(=O)C1Cc2ccc(O)cc2CN1CCF +O=C(c1cccnc1)N1N=C(c2ccc(O)cc2)CC1c1ccccc1Br +Oc1ccc2oc(-c3ccccc3OCc3ccccc3)cc2c1CN1CCC(N2CCCCC2)CC1 +Cc1ccc(F)c(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +COc1cccc2c1NC(=O)C(NC(=O)C(CCC(F)(F)F)C(CCC(C)(F)F)C(N)=O)N=C2c1ccccc1 +CCC(CC)=C(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1 +Cc1nc(NC2CCCC2)c2nnn(-c3ccc(C(C)C)cc3Br)c2n1 +CC1=CC(C2Oc3c(F)cc(F)cc3-c3ccc4c(c32)C(C)=CC(C)(C)N4)CCC1 +CN(Cc1ccccc1)C(=O)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 +CCCCCN1C(=O)C(=NNC(=O)CC(C)C)c2ccc(OC)cc21 +Nc1nc2ccc(S(=O)(=O)n3c(CCCC(=O)O)cc4cc(Cl)ccc43)cc2s1 +CN(C)c1ccc(-c2c(N)ncnc2C#Cc2ccc(N3CCOCC3)nc2)cc1 +Oc1ccc(CN(Cc2cccs2)Cc2ccc(O)c3ncccc23)c2cccnc12 +COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(CCN)c(F)c1 +COc1ccc2c(c1)-c1nc(-c3ccc(C4(N)CC(O)(C5CC5)C4)cc3)c(-c3ccccc3)n1CO2 +CC1(c2ccc(N)cc2)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O +CC(=O)OC(C(=O)Nc1cccc2c1C(=O)C(=O)NC2=O)c1ccccc1 +CNC(=O)N1CCCC1c1cc(-c2ccncc2)c(-c2ccc(F)cc2)[nH]1 +CCCOC1C(O)CC(=CC=C2CCCC3(C)C(C(C)SCCCC(O)(CC)CC)=CCC23)CC1O +COc1ccc2c(c1)-c1c(ssc1=S)C(C)(C)N2C(=O)c1ccccc1F +CNC(C)C(=O)NC(C(=O)N1CC2CCCN2CC1C(=O)NC1CCC(F)(F)c2ccccc21)C1CCCCC1 +COc1cc(CNCCCCN2CCC(Cc3ccccc3)CC2)cc(OC)c1OC +COc1ccc(S(=O)(=O)n2c(=O)cc(-c3ccccc3)c3ccccc32)cc1OC +COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cnc1C)C2=O +COc1ccc(C2(CNC(=O)c3cc(C)ccc3Cl)CCCC2)cc1 +Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccc(Cl)c(Cl)c2)C(NC=O)CC3)c1 +Cc1cc(-c2cccc(C(=O)c3cccc(O)c3)n2)ccc1O +COc1ccc(CNc2ccc(-c3ccc(CC(N)C(=O)O)cc3)nn2)cc1OC1CCCC1 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(F)cc3F)CC2)nc2ccsc12 +CC(C)=CCc1cc(C(=O)C=Cc2ccc(O)c(O)c2)c(O)cc1O +CC(C)(C)c1nc(N2CCN(CCCCN3CCC(=O)CCC3=O)CC2)cc(C(F)(F)F)n1 +FC(F)(F)c1cc(C(F)(F)F)c2[nH]c(N3CCN(c4ncccc4C(F)(F)F)CC3)nc2c1 +Cc1cc(NCC(N)c2cccc(F)c2)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +CC(C)Oc1ccnc2[nH]cc(-c3ccnc(N)n3)c12 +O=S(=O)(c1c(-c2nc3ccc(F)cc3[nH]2)[nH]c2ccc(Br)cc12)N1CCCC1 +CC(C)c1noc(-c2cc(Cl)nc(Oc3ccc4c(c3)N(S(=O)(=O)c3ccc(Cl)cc3)CCC4)c2)n1 +O=C(O)c1ccc(S(=O)(=O)N(Cc2ccc3occc3c2)c2ncc(C(F)(F)F)cc2Cl)cc1 +COc1cccc2cc(C(=O)NCCCCCCCNc3c4c(nc5ccccc35)CCCC4)oc12 +CC(C)c1ccccc1OCC(O)CN1CCC(N2C(=O)c3cccc4cccc(c34)C2=O)CC1 +CC(=O)N1CCc2ccc(C(=O)CCCN3CCC(c4ccc(Cl)cc4)CC3)cc2C1 +N#Cc1ccc(NC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +Cc1cncc(N2CC3CN(C(=O)c4ccc(F)cc4-n4nccn4)CC3C2)n1 +O=C(O)C12CCN(c3nc(-c4ccccc4OCc4ccc5c(c4)CCN(C4CCOCC4)C5)cs3)CC1C2 +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3n[nH]cc3C3(c4ccccc4)CC3)CC2)C(c2ccccc2)C1 +NS(=O)(=O)c1ccc(CNS(=O)(=O)c2c(F)c(F)cc(F)c2F)cc1 +CN(C)Cc1nccn1-c1ccc(N2CCC(NS(=O)(=O)c3cc4ccc(Cl)cc4s3)C2=O)c(F)c1 +CC(C)OC(=O)c1ccc(Oc2ccc3c(c2)COB3O)cc1 +CC(O)CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N(C)C)c1=O 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+O=C(CCCCCCc1ccccc1)c1ncc(CCCCCCl)o1 +Cc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc([N+](=O)[O-])c(N2CCNCC2)cc1Cl +O=C(Oc1ccc(Cl)cc1)N1CCN(c2nc(C3=NOC(c4ccccc4)C3)cs2)CC1 +COc1ccc2c(c1)c(CCN1CCCCC1)cn2S(=O)(=O)c1ccccc1 +Cc1ccccc1Oc1ccc(C=C(NC(=O)c2ccccc2)C(=O)O)cc1 +CC(C)c1cc(Oc2c(Br)cc(NC(=O)C(=O)O)cc2Br)ccc1O +Cc1nc(N)ccc1CNC(=O)C1C=CCn2c(=O)n(C(CSc3ccc(Cl)c(Cl)c3)C(=O)OC3CCCCC3)c(=O)n21 +NC1CCC(Nc2cc(-c3nc(NCC4CCOCC4)cnc3C(F)(F)F)c(Cl)cn2)CC1 +NS(=O)(=O)Cc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1 +CCc1cccc(C2(NCC(O)C(Cc3cc(F)cc(F)c3)NC(C)=O)CCCCC2)c1 +O=C(O)CCCCN1CCc2c(c3ccccc3n2Cc2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)C1 +O=C(Nc1cc2ccc(-c3cc(CO)ccc3Cl)cc2cn1)C1CC1 +COCCCN1CCN(C(=O)N2Cc3c(NC(=O)c4ccccn4)n[nH]c3C2(C)C)C(C)C1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(Cl)cc4)cc3)[nH]c2n(CCC)c1=O +N=C(N)c1ccc(NC(=O)COc2ccc(CC(NC(=O)c3ccc4ccccc4c3)C(=O)O)cc2)cc1 +CN(C)C(=O)Cc1ccc2nc(NC(=O)c3cccc(Cn4nc(-c5cccnc5)ccc4=O)c3)[nH]c2c1 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+CC1CN2c3c(cc4c(-c5ccccn5)noc4c3Cl)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +N#Cc1cccc(-c2cc(N3CC(N)C(c4cc(F)c(F)cc4F)C3)ncn2)c1 +Cc1cc(CN2CCCC(Nc3nc(N)n4nc(-c5ccco5)nc4n3)C2)no1 +CC(=O)N(C1=C(N(C)C)C(=O)c2ccccc2C1=O)c1cccc(O)c1 +CCC#CCOC1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 +CCc1c2c(nc3ccc(OCC[n+]4cccc(CO)c4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC +N#Cc1cc(-c2ccc3c(c2)C2(CCCCC2)C(S)=N3)ccc1F +FC(F)(F)c1ccnc(Nc2cc(-c3ccccc3)cc(N3CCOCC3)c2)n1 +COCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCCCC(N)=O)C(C)C)ccc1OC +COc1ccc(Cn2cc(-c3cc(C(F)(F)F)nc(S(C)(=O)=O)n3)ccc2=O)cc1 +CN1CCC(NC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +COc1ccc(CCN2CCC(c3nc(COCC(F)(F)F)c(-c4ccc(F)cc4)o3)CC2)cc1S(N)(=O)=O +CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccc(Cl)nc3)cc12 +CCN(CCCl)CCCCCNc1c2ccccc2nc2ccc(OC)cc12 +Cc1c(C#N)ccc2nc(CCc3nc(N4CCCC4)nn3C)nn12 +Cc1cc(N)nc2cc(CNCCc3ccc(C#N)cc3)ccc12 +CC(=O)Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cn1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1 +O=C(CC1CCc2ccccc2N1S(=O)(=O)c1ccc(Cl)c(Cl)c1)NCCN1CCN(c2ccncc2)CC1 +O=C1Nc2ccc(Cl)cc2C(C#Cc2ccccn2)(C(F)(F)F)N1 +Cc1cc(COc2ccc(C(=O)NC3CN(S(C)(=O)=O)CC34C(=O)NC(=O)NC4=O)cc2)c2ccccc2n1 +O=C(CO)NCC1CCCc2cc(S(=O)(=O)c3cccc(F)c3)ccc21 +O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccccc3)n(-c3ccc(Cl)cc3)n2)c1 +CN(CCCNc1c2c(nc3ccccc13)CCCC2)CCCNc1c2c(nc3ccccc13)CCCC2 +Cc1nc(-n2ccc(C3CC3)cc2=O)sc1C(=O)NCc1ccccc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccccc4-n4ccnc4)nc23)N1 +Nc1nc(=S)[nH]c2c1c(-c1ccc(Br)cc1)cn2-c1ccc(S(N)(=O)=O)cc1 +Clc1ccc(OCCc2ccccc2)c(CCN2CCOCC2)c1 +CCOC(=O)C1=C(C)N=C(C[S+]([O-])c2ccc(OC)cc2)C(=C(O)OCC)C1c1ccccc1C(F)(F)F +COC1C(c2ccc(C#N)c(Cl)c2C)=NN2CC(F)CC12 +O=C(NC1CCNCC1F)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CN(c1ncnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12)C1CCCCC1 +Cc1cc(COc2ccc(NC(=O)C3C(C(=O)NO)CCCN3CC3CC3)cc2)c2ccccc2n1 +NC(=O)c1cccc2[nH]c(-c3ccc(CN4CCOCC4)cc3)nc12 +CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCN(C2CCN(C(=O)OC(C)(C)C(F)(F)F)CC2)CC1 +Cn1nc(S(N)(=O)=O)sc1=NS(=O)(=O)c1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +O=C1CCCC(=O)C1C(=O)c1ccccc1[N+](=O)[O-] +CN1CCC(COCc2cc(C(F)(F)F)cc(N3CCC(C#N)CC3)n2)(c2ccc(F)cc2)CC1 +O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(OCC23CC4CC(CC(C4)C2)C3)cc1F +CN(C(=O)C1CCCCC1)c1ccc2c(c1)nc(NC(=O)c1ccc(C#N)cc1)n2CCc1ccccc1 +CC(NC(=O)Nc1cc2[nH]nc(-c3ccc4nn(C)cc4c3)c2cn1)c1cccc(Cl)c1 +Cn1ncc(NC(=O)c2nc(-c3c(F)ccc(F)c3F)sc2N)c1C1CCC(N)C(F)CO1 +CCCCCC(O)C1C(=O)NC(C(=O)O)(C(O)C2C=CCCC2)C1(C)O +CCOC(=O)CNC(=O)c1ccccc1[Se][Se]c1ccccc1C(=O)NCC(=O)OCC +Cc1ccc(NC(=O)c2cccnc2SCc2ccncc2)cc1C +COc1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 +Clc1ccc(-c2cc(C3CCN(Cc4cccc(Cl)c4)CC3)[nH]n2)cc1 +Nc1c2ccccc2nc2c(C(=O)NC34CC5CC(CC(C5)C3)C4)cccc12 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(C(F)(F)F)c4)c3)cc12 +CC(=O)OC(C(=O)Nc1cnn(Cc2c(C)noc2C)c1)c1ccccc1 +CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1cc(O)ccc1n2CCF +COc1ccc(S(=O)(=O)Nc2ccc3nc(NC(C)c4ccccc4)oc(=O)c3c2C)cc1 +O=C(Cc1ccc(F)cc1)Nc1cccc(-c2n[nH]c3ccc(-c4nc[nH]n4)cc23)c1 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+O=C1CC(C(=O)Nc2cc(-c3cccc(OCC(F)(F)F)c3)n(-c3ccccc3)n2)CN1 +CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc4c(C(N)=O)cccc4c3)n2)c1 +CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(O)cc3)c(O)nc12 +CS(=O)(=O)Nc1ccc(-c2coc3cc(C#CC4CN(C(=O)CO)C4)ccc3c2=O)cc1 +O=C(Nc1cc(-c2cn[nH]c2)cc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1 +O=C(c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1)c1cccs1 +CC1CC(O)C2(O)OC3CC4(CO)C(CCC5C4CC(O)C4(C)C(C6=CC(=O)OC6)CCC54O)CC3OC2O1 +CCCC(=NNS(=O)(=O)c1cc([N+](=O)[O-])ccc1C)c1cnn2ccc(C#N)cc12 +C#Cc1cccc2nc(Cn3nc(-c4cccc(O)c4)c4c(N)ncnc43)n(Cc3cccc(OC)c3)c(=O)c12 +COc1c(C)cccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 +Cc1ccc(C=CC(=O)c2ccc(O)c(CN3CCOCC3)c2)o1 +O=C(NC1CCOC2CCCC(C(=O)O)N2C1=O)C(S)Cc1ccccc1 +Cc1ccc(S(=O)(=O)N(CC(C)C)C(CCCCNC(=O)N(C)Cc2ccccc2)C(=O)O)cc1 +O=C(Oc1ccc(-c2ccc(F)cc2F)cc1C(=O)Nc1cccc(Cl)c1)c1ccccc1 +CN(CCCCn1c(=O)oc2ccccc21)Cc1ccc(Cl)cc1 +NC(=O)c1ccccc1OCCCN1CCN(c2cccc3c2ccn3Cc2cccc(Cl)c2)CC1 +COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4ccco4)cc3)C2C2CCCCC2)cc1 +CC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C1c1cc(F)c(F)c(F)c1 +CC(C)(C)ON=C(c1cc(Br)c(F)cc1O)c1c(O)ccc[n+]1[O-] +CCNC(=O)C1OC(n2cnc3c(N)nc(C#CC(OCC)OCC)nc32)C(O)C1O +CNC(=O)C1Cc2ccccc2N1C(=O)Cc1ccc(Cl)cc1 +Cc1ccccc1-c1ccc2nc(N)c(CC(C)C(=O)NCC3CCCCC3)cc2c1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCCN(C(=O)OCc3ccccc3)CC2)cc1 +O=C(OCc1ccccc1)N(O)CCC#Cc1ccc(OCCCCN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +Cn1ncc2c(Nc3nc(NC4CCCCC4N)nnc3C(N)=O)cccc21 +COCC(NC(=O)Nc1cc2[nH]nc(NC3COC3)c2cn1)c1ccccc1 +O=S(=O)(NCCCCc1c[nH]cn1)c1ccc(OC(F)(F)F)cc1 +OC1C(Cn2cncn2)OC(c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)C(O)C1O +NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +CC(C)Cn1c(=O)n(C)c(=O)c2[nH]c(Cc3cncc4ccccc34)nc21 +Nc1noc2cccc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 +COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +O=C(c1cccc2ccccc12)N1Cc2ccccc2CC1COc1ccc(F)cc1F +Cc1oc(-c2ccccc2)nc1CCOc1ccc2c(c1)CCC2C(CC(F)(F)F)C(=O)O +O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1cc(Cl)cc(Cl)c1 +CCn1cc(-c2cc3c(-c4cccc(N5CCNCC(C#N)C5)n4)n[nH]c3cn2)cn1 +O=C(O)c1ccc(CNC(=O)c2cc(Cl)ccc2Oc2ccc(F)cc2)cc1 +N#Cc1ccc(C(=O)Nc2ccc(F)c(C34CC3CCSC(N)=N4)c2)nc1 +Cc1ccc(NC(O)c2ccc(CN3CC(N(C)C)C3)c(C(F)(F)F)c2)cc1Nc1nccc(-c2cncnc2)n1 +CC1(C)CC(=O)CC(=NNC(=O)c2cc3ccccc3cc2O)C1 +COc1cc(OC)nc(Sc2cccc([N+](=O)[O-])c2C(=O)O)n1 +COc1ncccc1-n1nc(C)c2c1C(=O)N(c1cc(C)c3nnc(C)n3c1)C2c1ccc(Cl)cc1F +CCCC1(CCc2ccccc2)OC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3ccc(C#N)cc3)c2)=C(O)O1 +CC(C)C1CN(C(=O)Nc2ccccc2)c2ccc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)cc2O1 +Fc1ccc(C2=NN(c3nc(-c4ccc(Br)cc4)cs3)C(c3cccs3)C2)cc1 +CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3cccs3)cc2)C1c1cccc[n+]1[O-] +CN1CCN(Cc2ccc(-n3cc4cccc(C(N)=O)c4n3)cc2)CC1 +O=C(Cc1ccc(F)cc1)Nc1ccc2cc(C(=O)NO)sc2c1 +Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2nc(-c3ccccc3)oc12 +COc1cccc(CNc2ccc3c(c2)C24CCCCC2C(C3)N(CC2CCC2)CC4)c1 +Brc1ccc2[nH]cc(C(c3ccccc3)c3c[nH]c4ccc(Br)cc34)c2c1 +Cc1ccc(-c2csc(NN=C3CCc4c(C)cccc43)n2)cc1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC(C)CN)CC2)CC1 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+O=C(Nc1cnc(Oc2ccc(-c3cnc(N4CCCC4=O)s3)cc2)nc1)Nc1cc(C(F)(F)F)cnc1-c1ccccc1 +NC(=O)c1cccc2c(NCC3CC=CC(=NC(O)c4ccn[nH]4)C3)ncnc12 +COc1cc(OC)cc(-c2cc3cnc(NCCCN4CCOCC4)nc3nc2NC(=O)NC(C)(C)C)c1 +Cc1cccc(-c2nc(Nc3ccncc3)c3sccc3n2)n1 +O=C(CN1C(=O)C2(OCCO2)c2ccccc21)c1cccc(Br)c1 +CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(C=CC#N)c1 +COc1ccc(CNC(=O)COc2ccc(-c3oc4cc(O)c(C(=O)O)cc4c3C#Cc3cccc(Cl)c3)cc2)cc1OC +Cc1ccc(-c2ccc(N3CCOc4ncnc(N)c4C3=O)cc2)c(Cl)c1 +Cc1cccc(N2CCN(Cc3ccc(F)cc3Cl)C(=O)C2=O)c1N1CCOCC1 +Cc1ccc(C)c(Cn2cc(CCNc3ncnc4c3ncn4C3OC(C(=O)NC4CC4)C(O)C3O)c3cc(C)ccc32)c1 +COc1cccc(NC(=O)Cn2cc(Oc3ncnc4cc(OCCN5CCCC5)c(OC)cc34)cn2)c1 +O=C(Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1)NCc1ccc(-c2ccccc2)cc1 +NC1=Nc2ccc3cc2CN1C(C1CCCCC1)CCC(=O)N(C1CCCCC1)CCc1cccc(c1)O3 +CCS(=O)(=O)Nc1ccc(CCNC(=O)c2ccnc3[nH]c(-c4ccc(F)cc4)nc23)cc1 +CCOCCC1(Oc2ccc(Oc3ccc(Br)cc3)cc2)C(=O)NC(=O)C(N)C1=O +CN1CCC(c2ccc(Nc3nc4c(Nc5ccccc5CN(C)S(C)(=O)=O)cccn4n3)cc2)CC1 +CSc1cccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(C)c(Cl)c2)c1 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+COc1cc(C2OC(c3ccc(OC(C)C(O)c4ccccc4)c(OC)c3)C(C)C2C)ccc1OC(C)C(O)c1ccccc1 +CC1C(Nc2ccc(C(F)(F)F)cn2)CCCN1C(=O)c1cc(Cl)ccc1-n1nccn1 +COc1cc(CC2CN=C(N)N=C2N)cc(OC)c1OCc1ccccc1 +CCc1c(C(=O)Nc2cc(S(=O)(=O)N(CC)CC)c(C)cc2O)[nH]c(C)c1C(C)=O +O=C(O)c1ccc2c(c1)nc(NCc1cccnc1)c1ccsc12 +CCCS(=O)(=O)N1CCC(CNC(=O)c2cccc(C)c2)(c2ccccn2)CC1 +COc1ccc2c(c1Cl)C(=O)N(Cc1c(C)cc(C)[nH]c1=O)CCC2 +CNC(C(=O)NC(C(=O)N(C)C(CC(C)C(=O)O)C(C)C)C(C)(C)C)C(C)(C)c1cn(C)c2ccccc12 +C#CCNC1CCc2ccc(OC(=O)N(C)c3ccc(OC)cc3)cc21 +COc1ccc(C(=O)Nc2nc(-c3ccccn3)cc3ccccc23)cc1 +O=C(NCP(=O)(O)CC1(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O)CCCC1)OCc1ccccc1 +CNC(=O)c1ccc2[nH]c(-c3ccc(Oc4c([N+](=O)[O-])c(C)nn4-c4ccccc4)cc3)nc2c1 +O=C(NC(Cc1ccc(F)c(Br)c1)C(=O)O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12 +Oc1ccc(C2Nc3ccccc3-c3ccnc4[nH]cc2c34)c(F)c1 +CC(C)CC(NC(=O)C1OC1C(=O)O)C(=O)NCCCCNC(=O)CCCCC1CCSS1 +CC(=O)NC(COCc1cc(C)cc(C)c1)Cc1c[nH]c2ccccc12 +CC(C)(C)OC(=O)Nc1cccc(CCNC(=O)CC2(C)CC3(CCCCC3)OO2)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2-c1ccc2cn[nH]c2c1 +N#Cc1c(-c2ccccc2)nc2[nH]nc(C3CC3)c2c1-c1ccccc1 +NC(=NO)c1cn(C2OC(CO)C(O)C2O)c2nnnc(N)c12 +c1ccc(-n2cnc3cc(-c4ccc(OCCN5CCCCC5)cc4)ccc32)cc1 +Nc1cc(CN2CCC(F)(C(=O)N3CCC(N4CCNc5ccccc5C4)CC3)CC2)ccn1 +CC(C)CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +O=C(CC1CCCC1)Nc1ccc(NC(=O)N2Cc3ccc(Br)cc3C2)cc1 +CN1C(=O)CN(Cc2ccc(-c3cccc(CN4CCCCC4)n3)cc2)C1=O +Cc1ccc(C(=O)c2oc3cccc(OCCCNCc4cccnc4)c3c2C)nc1 +Cc1cc(C#N)ccc1C1CCN(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)OC3CCNC3)CC2)CC1 +CCC(C)c1ccc(OS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +CS(=O)(=O)c1ccc(-c2sc3ncnn3c2-c2cccc(F)c2)cc1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(C)C2 +CN(C)C(=O)c1cc(-c2ccc(Cl)cc2Cl)n[nH]1 +CCC(C)c1ccc(O)c(NC(=S)NC(=O)c2cccnc2)c1 +CCOC(CC(=O)O)c1ccc(Oc2ccc(Cl)c(Cl)c2)cc1 +CC=CC=CC(=O)N1Cc2cc(OCCc3nc(C(C)=CCC)oc3C)ccc2CC1C(=O)O +CC(=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccccc3)CC2C(C)(O)O)c1 +CCCCN(CC)Cc1cnc(NC(=O)C(CCC)NC(=O)Cc2cc(F)cc(F)c2)s1 +COc1ccc(-c2ccc(C(=O)Nc3ccc4cc(CN5CCCC5)cnc4c3)cc2)cc1 +CON=C1C(c2c(O)[nH]c3cc(Br)ccc23)=Nc2ccccc21 +CC12CCC(=O)C(Br)=C1c1ccc3[nH]ncc3c1C2 +CC(C)C1(c2cccs2)OCC(=O)Nc2ccc(-c3ccc(C#N)n3C)cc21 +O=C(NCc1ccc(F)cc1)c1nc(Cc2ccccc2)nc(O)c1O +CC(CN1CC(C)(C)c2cc(F)ccc21)NC(=O)OC(CC1CCCCC1)C(=O)N1CCSCC1 +CCCCCN1CCc2cc(C(=O)CCC3CCN(Cc4ccccc4)CC3)ccc21 +CC(C)(C)c1ccc(C2(N3CCc4cc(S(=O)(=O)Nc5ccc(CCCC6CCCC6)cc5F)ccc4C3)CC2)cn1 +COc1ccc(C(C(=O)N2Cc3ncn(Cc4ccccc4)c3CC2C(=O)O)c2ccc(OC)cc2)cc1 +Cn1cc(CNC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)cn1 +CC(=O)c1ccc(CN2CCC(Nc3cc(Oc4c(C)cc(C)cc4C)n4ncnc4n3)CC2)cc1 +COc1cccc(-c2cn(C3CC(CNCCO)C3)c3ncnc(N)c23)c1 +CCCCCCCCCCCCCCONC(=O)C(N)COP(=O)(O)O +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(N3CCOCC3)c2cn1)c1ccccc1 +CCCCc1ccc(-c2ccc3c(C)c(-c4ccc(C(=O)O)c(O)c4)[nH]c3c2F)cc1 +O=C(NO)C(CNS(=O)(=O)c1cccc(C(F)(F)F)c1)NS(=O)(=O)c1cccc(C(F)(F)F)c1 +Nc1nc(Cl)c2ccn(C3OC(CO)C(O)C3O)c2n1 +CCCC(C(=O)NO)C1CCN(c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1=O +CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C1CC1 +CCCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(C(=O)O)c(C)nc3ccccc23)cc1 +Fc1cc(Cl)ccc1C(c1cccnc1)N1CCN(c2ccccc2)CC1 +O=C(NCCCCNc1ccnc2cc(Cl)ccc12)C(=O)NC1C(=O)N(c2ccc(Cl)cc2)C1C=Cc1ccccc1 +CN(CC1(C)Cn2cc([N+](=O)[O-])nc2O1)c1ccc(OC(F)(F)F)cc1 +O=C(C=Cc1cccnc1)N1CCN(Cc2ccc(OC(F)(F)F)cc2)CC1 +CCCN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(c3ccc(OC)cc3)=NN12 +CN(c1ccc(Cl)cc1)c1ccc(C(=O)c2ccc(C(=O)c3cccs3)c(C(=O)O)c2)nc1 +O=C(Nc1nc2ccccc2c2cn(-c3ccccc3)nc12)c1ccsc1 +O=C(Nc1ccc(-c2ccccc2)cc1)C1CCCN1c1ccc(-n2ccnc2)cc1 +CN(C(=S)SSC(=S)N(C)c1ccccc1)c1ccccc1 +COc1cc2c(cc1OC)C(=O)N1C=C(c3c(F)cccc3F)CC1C=N2 +COc1cc(Nc2nnc(-c3ccccc3)o2)ccc1-c1cnco1 +Cc1cccc(OCC2CC3CCC2N3C(=O)c2ccccc2-c2nc(C)no2)n1 +N=C(N)c1ccc2cc(C(=O)Nc3ccc(C(N)=O)cc3)ccc2c1 +CS(=O)(=O)c1ccc(CN2CCN(c3cn[nH]c3-c3cc(Cl)c(O)cc3O)CC2)cc1 +CCOc1c(Cl)cc(Cl)cc1-c1cnc(C(C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1 +COc1ccc(COc2cc(C(N)=O)c3ncnc(NC(CN(C)C)c4cccc(F)c4)c3c2)cc1 +CNc1cc(-c2ccc(N3CCN(C)CC3)cc2)c(-c2cc(F)c(O)c(F)c2)cn1 +C=CCOC(=O)c1c(C)[nH]c2c1C13CC1CN(C(=O)C=Cc1ccc(OC)cc1)C3=CC2=O +Cc1cc(C(N)=O)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(-c2ccoc2)cc1 +CC(C)(C)OCC(O)CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +COC1CCC(Nc2ccc3nnc(-c4cccc(C(F)(F)F)c4)n3c2)CC1 +O=C(c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cc1)N1CCCCC1 +N#CCC(=O)N1CCC(F)(F)C12CCN(c1ncnc3[nH]ccc13)C2 +Cn1cc(-c2cccc(N3CCn4c(cc5c4CCCC5)C3=O)c2CO)cc(Nc2ccc(N3CCOCC3)cn2)c1=O +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cnn(-c4ccccc4)c3)c(C(=O)O)n1)CC2 +CN(CC(CCN1CCCCC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +CCCCCC(O)c1ccc(N2C(=O)CCC2COCc2ccc(C(=O)O)o2)cc1 +NC1=NC(CCc2ccc(OC(F)(F)F)c(F)c2)CO1 +CC(Oc1cccc(C#Cc2ccc3ccc(Br)cc3n2)c1)C(=O)O +CC1CC(c2ccccc2-c2ccccc2)N(Cc2ccc(OC(F)(F)F)cc2)C1=O +CNC(=O)C1CCCN1c1nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)nc(OC)n1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4cccc(-n5cnnn5)n4)CC3CO2)c1C +CCc1cc(C(=O)NC2CC(C(=O)Nc3ccccn3)N(C(=O)c3coc4ccccc34)C2)n(C)n1 +O=C(CCC1CCN(Cc2ccccc2O)CC1)c1cc2c3c(ccn3C(=O)CC2)c1 +Cc1cc(C)c(S(=O)(=O)NC(C)CNc2cccc3c2cnn3-c2cncnc2)c(C)c1 +CCOC(=O)C1CCCN(C(=O)CCC(=O)N(CC(C)(C)C)c2ccc(Cl)cc2C(O)c2ccccc2OC)C1 +NC1=CC(=O)c2ccc(-c3nc(C(=O)OCCO)cc4c3[nH]c3ccccc34)nc2C1=O +S=C(Nc1cccc(Cl)c1)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +O=C(Nc1ccc2cc(C(=O)NC3CN4CCC3CC4)sc2c1)Nc1c(F)cccc1F +COc1ccc(-c2cnc(C3C(c4ccc(Cl)cc4)CC4CCC3N4C)s2)cc1OC +O=C(CCN1CCC(c2nc(-c3cnccn3)no2)CC1)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1 +CN1CCN(C(=O)c2cc3cc(Cl)cc(N)c3[nH]2)CC1 +N#Cc1ccc(-c2nc(NCCNc3ccc([N+](=O)[O-])cn3)ncc2-n2cncn2)cc1 +CN1CCN(CCn2ccc3c(N4CCOCC4)nc(-c4ccc(NC(=O)Nc5ccncc5)cc4)nc32)CC1 +CNCc1ccc(-n2cc3cc(F)cc(C(N)=O)c3n2)cc1F +O=C(NCCCN1CCC(c2noc3cc(Cl)ccc23)CC1)c1nsc2ccccc12 +O=c1[nH]nc2cc(CNC3CCCNC3)c3ccc(-c4ccc[nH]4)cc3n12 +CC(=O)c1cccc(-c2ccc3oc(CCN4CCCC4C)cc3c2)c1 +CCCCC(N)C(=O)Nc1cc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O)ccc1N +O=C(O)c1ccc(O)c(C=NNC(=S)NC2CCCCC2)c1 +O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1cc2ccccc2s1 +O=C(O)COc1cccc(CC2CCCCC2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1 +Cc1nc(C)c(CNc2nc(OCC3CC3c3cc4ccccn4n3)nc(Cl)c2C)s1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(N5CCNCC5)cc4)nc23)N1 +CC(=NNC(N)=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +COc1ccc2c(c1)c(CC(C)C(=O)O)c(C)n2Cc1ccc(Br)cc1 +CCOc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cc1F +O=C(O)CCC1CCc2cc(-c3cc(OC4CCC4)ncc3F)ccc2O1 +Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCCCCn2ccnc2)cc1Cl +O=C1NCC(c2ccsc2)CCC1NC(=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1 +NS(=O)(=O)c1ccc(CCn2c(=O)c3ccccc3c3ccccc3c2=O)cc1 +Cn1c(-c2ccc3ccccc3c2)nnc1-c1ccccc1C(F)(F)F +CC1CCCCC1Oc1nc(N)c2c(=O)ccn(C3COCC3O)c2n1 +COC(=O)c1c(-c2c(Cl)cccc2Cl)noc1NC(=O)NN1CCCCC1 +CCCC1CN2C(=N1)N(CC)C(=O)c1nc(Cc3ccccc3)n(Cc3ccccc3)c12 +CN(C)Cc1ccn2c(-c3ccnc(NCC(C)(C)C)n3)c(-c3ccc(F)cc3)nc2c1 +NC1=NCN=C2C1N=CN2C1OC(CSCCF)C(O)C1O +CCc1c(C(C)c2c(F)cccc2Cl)nc(SC(C)CC)[nH]c1=O +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccncc1)CC2 +CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2Cl)cc1 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+O=C(OCc1ccccc1F)N1CCC(CNc2ncccn2)CC1 +CN1CCC(CNC(=O)c2cc(Cl)cc(Cl)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +Cc1noc(C(=Cc2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 +CNC(=O)OCc1c(COC(=O)NC)c(-c2ccc(OC)c(OC)c2)n2c1Cc1ccccc1-2 +O=C(Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)cc1)c1cccc(F)c1 +CNc1nc(Nc2cc(F)c(C(=O)N3CCOCC3)cc2OC)ncc1C(F)(F)F +COC(=O)c1sc2cc(C)ccc2c1Nc1cc(OC)c(OC)c(OC)c1 +CC(F)(F)c1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c1 +COc1ccc(COc2ccc3c(c2)OCC3CC(=O)O)cc1-c1c(C)cccc1C +CN(C)C(=O)n1cnc(S(=O)(=O)C2CC3CCC2C3)n1 +c1ccc2nc(CCCCN3CCc4c([nH]c5ccccc45)C3)ccc2c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1COc3ccccc31)CC2 +CN1CCN(Cc2cccc(C(=O)NCc3cccc(-c4cccc(CN5CCNCC5)c4)c3)c2)CC1 +O=C(O)c1ccc(N2CC3(CCN(Cc4nc(-c5ccccc5)oc4-c4ccccc4)CC3)OC2=O)cc1 +COc1ccc(-n2nnc(-c3ccccc3NC(=O)c3cccc([N+](=O)[O-])c3)n2)cc1 +CN(C)c1ccc(C(=O)NC(CCCCCC(=O)NO)C(=O)Nc2cccc3cccnc23)cc1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(C)CCCc3ccccc31)CC2 +c1ccc(-c2cc(NCc3cccnc3)n3ncc(C4CC4)c3n2)cc1 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+CN1CCc2cc(N)cc3c2C1Cc1ccc(O)c(O)c1-3 +CC(=O)N1c2ccc(NC(=O)c3ccc(-c4ccccc4)cc3)cc2C(C)(c2ccc(C)cc2)CC1(C)C +COc1ccc(NC(=O)CN(C)C(=O)C2=COCCO2)cc1 +CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(-n3ccc4ccc(F)cc43)ccc2=O)c1 +CC(C)(C)OC(=O)NC(CSCCC(=O)NCc1cccnc1)Cc1c[nH]c2ccccc12 +COC(=O)C1=C(CN2CCOCC2)NC(c2ccccn2)=NC1c1ccc(F)cc1Cl +Cc1ccc(NC2=C(Cl)C(=O)c3nc(C)[nH]c3C2=O)cc1 +OCc1ccc(Oc2cccc(-c3c(-c4ccccc4)cnc4c(Cl)cccc34)c2)cc1 +CC(C)(C)c1ccc(C(=O)NC(=S)Nc2ccc(NC(=O)c3ccccc3)cc2)cc1 +CN(C)C1Cc2ccccc2C(c2cccc(-c3ccccc3)c2)C1 +Cc1ccc(S(=O)(=O)N2CCN(c3ncccc3C#N)CC2)cc1 +NS(=O)(=O)c1ccc(NNC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +COc1cccc(F)c1-c1cccc2nc(NC3CCCCC3)oc12 +O=C1NCN(c2ccccc2)C12CCN(C1CCc3ccccc31)CC2 +CC1(C)CCC(C)(C)c2cc(C(=O)Nc3cc(F)c(C(=O)O)c(F)c3)c(O)cc21 +COc1cccc(OC)c1-c1ccc(CC(NC(=O)C2(c3cccc([N+](=O)[O-])c3)CCCO2)C(=O)O)cc1 +CC(C)(C)OC(=O)NCC1CCC(CNC(=O)c2cc(-c3ccccc3)nc3[nH]ccc23)CC1 +NC(=O)c1ccc2[nH]c(-c3ccc(OCC4CCN(Cc5ccc(Cl)c(Cl)c5)CC4)cc3)nc2c1 +COc1ccc(Nc2cc(-c3cccc(C(=O)Nc4ccc(C(=O)O)cc4)c3)nn3ccnc23)nc1OC +COc1ccc(C2CC(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1 +CNc1cccc(CCOc2ccc3c(ccn3CCC(=O)O)c2)n1 +COc1cc(-c2nc(C(F)(F)F)cn2-c2ccc(S(C)(=O)=O)cc2)ccc1Cl +O=C(CCCN1CCN(c2ccc(F)cc2)CC1)NC1c2ccccc2Oc2ccccc21 +CC12CCC3C4(C)CCCC(C)(C(=O)O)C4CC(O)C3(CC1=O)C2 +CN1CCC(OC(c2ccccc2)c2ccc(Cl)cc2)CC1 +CCc1ncnc(-c2ccc(N(C)C)nc2)c1C#Cc1ccc(N)nc1 +COc1ccc(C(F)Cn2ccnc2O)cc1OC1Cc2ccccc2C1 +Cc1cccc(C(=O)N2c3ccccc3C(=O)OC2c2ccc3c(c2)OCO3)c1 +CCc1nc(C)cn1-c1ccc2nc(O)c3c(C)nc(CC)n3c2c1 +CCOC(=O)N1CCC(N2CCCC(NC(=O)c3ccccc3)C2)CC1 +Cc1c(Cn2cc(C(=O)NCCF)c3ncccc32)ncnc1N(C)C +CN(CCNC1CCNc2c(Cl)cc(Cl)cc21)c1nc2nc(Cl)ccc2[nH]1 +CN1CCN(c2ccc(NC=C3C(=O)NC(=O)c4ccc(-c5ccoc5)cc43)cc2F)CC1 +COCCOc1cc2nc(-c3ccccc3O)nc(NC3CCNC3)c2cc1OC +COc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3Cl)nn2)s1 +Cn1cc(C2=C(c3cnc4ccccn34)C(=O)NC2=O)c2cc3c(cc21)OCO3 +CCCCCCN1CCC(c2ccn3c(-c4ccnc(N)n4)c(-c4ccc(F)cc4)nc3c2)CC1 +NC(CC(=O)N1C(C(=O)NCC2CC2)CC2CCCCC21)Cc1cc(F)c(F)cc1F +COc1ccc(-c2sc3c(c2CN(C)Cc2ccccc2)c(=O)n(-c2ccccc2)c(=O)n3Cc2c(F)cccc2F)cc1 +Cc1c(-c2nnn(C(C)C)n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCNC2CCOCC2)CCCC1)c1cc2ccccc2s1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)Nc1cnc(N2CCOCC2)nc1 +Nc1nc(N)c(SCCc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)c(O)n1 +COC(=O)c1ccc(C(=O)CN2C(C(=O)c3ccccc3)=C(O)c3ccccc3S2(=O)=O)cc1 +COc1cccc(C=NN(C(=O)C(F)(F)F)c2ccc(CO)cc2C)c1 +CCOn1cc(C2=NC(c3ccc(F)cc3)(c3ccc(F)nc3)C(C)N2)ccc1=O +CCn1c(=O)ccc2cnc(Nc3ccc(N4CCCCC4)cc3)nc21 +CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC(C)(O)CC2 +CC(C)CS(=O)(=O)N1CCCC(Nc2ncccc2-c2cnc3[nH]ccc3n2)C1 +COc1nc2c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c(F)cnc2cc1F +CCN(CC)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc3c(c2)OCCN3)c(F)c1 +Cn1cc(-c2ccccc2)nc1SCc1cn2c(Cl)cccc2n1 +O=C(Nc1ccc(COC2CCNC2)cc1)c1ccc(Cl)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CN)c4ccccc4)ncc23)ccn1 +COc1nn2cc(-c3cc4c(OCc5cccc(OCc6ccccc6)c5)cc(OC)c(Cl)c4o3)nc2s1 +CC(C=CC(=O)NO)=CC(C)C(=O)c1ccc(N(C)C)cc1 +Nc1ncc2ccc(Cl)cc2c1C#Cc1ccc(C2=NC(C3CC3)CN2)cc1 +CC1(CCCCN2CCSCC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 +O=C(O)C(Cc1ccc(I)cc1)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CC(C)c1nnn(-c2c(Cl)cccc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +O=C(c1ccc(O)cc1O)N(Cc1ccsc1)c1ccc(-c2ncnc3cccc(F)c23)cc1 +CS(=O)(=O)Nc1ccc(-c2cnccc2C2CC2)c(C(F)(F)F)c1 +O=C1N(c2ccc(C3CCC(N4CCC4)CC3)cc2F)CCC12CCNCC2 +C1=C[N+]2=C(C1c1cccc3ccccc13)C1c3ccccc3C2CC1(c1ccoc1)c1ccoc1 +CCCC(C)n1c(CC)nc2c(-c3ccc(OC)cc3C(F)(F)F)ccnc21 +CC1(C)CCCC2(C)c3c(oc4c(C(N)=O)c(O)c(O)cc34)CCC12 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2ccc(F)c(C#N)c2)C1 +COC(=O)c1cc(NC(=O)C(C)(C)Cc2ccc(C(=O)Oc3ccc(C(=N)N)cc3F)s2)cc(C(=O)OC)c1 +CCC(CC)(Cc1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1)C(=O)O +Cc1nc2nc(-c3ccc(CN4CC(c5n[nH]c(-c6ccccn6)n5)C4)cc3)c(-c3ccccc3)c(C)n2n1 +Cc1cc(C)c(C(=O)n2nc(Nc3ccc(S(N)(=O)=O)cc3)nc2N)s1 +Nc1ncc(-c2ncccc2C(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)(CCO)CC1 +CCCc1cc2c(=O)n(C(C)C)oc2c(CCC)c1OC(C(=O)O)c1ccc(C(C)C)cc1 +O=S(=O)(c1ccccc1)C1(F)CCN(CCc2ccc(F)cc2F)CC1 +CCc1ncnc(-c2ccc(C(=O)N3CCOCC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCCOc1ccc(Oc2ccc(-c3ccc(C(C)NC(=O)COC)cc3)cc2)cc1 +CCCCCC(=O)Nc1ccc(C(=O)Nc2cccc(CC(C)C(=O)O)c2)cc1 +CN(Cc1ccccc1)C(=O)C(Cc1ccc2ccccc2c1)NC(=O)C1CCCN1C(S)=NCc1ccccc1Cl +COc1cccc(-c2cc(C(=O)Nc3cc4ccc5c(c4oc3=O)NC(=O)C(CCNC3CCCCC3)O5)ccc2OC)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CNC4CC4)c(O)ccc3nc2-1 +COc1ccc2c3c1OC1C(OC)C(C)CC4C(C2)N(C)CCC341 +O=c1cc(-c2cccc([N+](=O)[O-])c2)[nH]c2c(-c3cccs3)c(C(F)(F)F)nn12 +Cc1c(S(=O)(=O)NCc2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)cnn1C(C)C +NC1(c2ccc(-c3nn4c(-c5ccc(F)cc5)c(Cl)nc4cc3-c3ccccc3)cc2)CCC1 +O=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccccc1-n1nccn1 +COC(=O)c1c(F)cccc1-c1ccc(C(C)NC(=O)C2(NC(=O)CC(F)(F)F)CC2)c(F)c1 +COC1CCC(C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +Clc1cccc(N2CCN(CCCCOc3cc4ccccc4cn3)CC2)c1Cl +Cc1cc(CNC(=O)c2ccc(N3CCC(Oc4ccccc4Cl)CC3)nn2)on1 +CCc1cc(-c2noc(-c3cc(OC)cc(CC(C)C)n3)n2)cc(C)c1OCC(O)CNC(=O)CO +CC(C)(C)NC(=O)NCCCc1nc2cc(S(=O)(=O)NCc3ccc(F)cc3)ccc2n1Cc1ccccc1 +Cc1ncn(-c2nccc3c(S(=O)(=O)N4CCN(C(=O)c5ccccc5)CC4C)c[nH]c23)n1 +Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc4ccc(Br)cc34)s2)n1 +CC(=O)N1CCN(C(=O)c2cc3c(s2)CCN(c2cccc(-c4nc5ccccc5n4C)c2)C3)CC1 +CN(C)CC1(c2ccc(-c3c(O)ccc4[nH]c(=O)c5sccc5c34)cc2)CC1 +Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1cccs1)CC2 +Cc1nc(N2CCC(N3CCCC3C)C2)ccc1NC(=O)Cc1ccccc1 +Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(C2CC2)cc1Cl +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ON=C1CCCCCN1 +COc1cc(-c2cccc(OC(C)C)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3cccnn3)ccc21 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C(F)(F)F)nc2C)n1 +O=C(NC1CCCCC1O)c1cnc(OCC2CC2)c(-c2ccc(Cl)cc2)c1 +CC(=O)N1CCc2c(c(-c3ccc(Cl)c(C)c3)nn2CC(O)CN2CCC(n3c(O)nc4ccc(Cl)cc43)CC2)C1 +Cc1nc2ccc(-n3cnc4cnc5cnc(-c6ccccc6)cc5c43)cc2s1 +Nc1cccnc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 +CC1(C)CCN(c2ccc(C#Cc3cc(F)ccc3F)cn2)C(=O)O1 +C#CCN(c1ccc(C#N)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +Cc1cccc(-c2cc(N(CCCN3CCCCCC3)Cc3ccc4c(c3)OCO4)on2)c1 +Cc1ccc(C#N)cc1C#Cc1ccc(CCC(=O)O)cc1 +COC12C(COC(N)=O)c3c(O)c(N=C4C=CC(=O)C(I)=C4)c(C)c(O)c3N1CC1NC12 +CC(=O)c1ccc(-c2sc(N)nc2-c2ccc(P(=O)(O)O)o2)cc1 +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ccccc2)CC1 +O=C(CCc1ccc(Br)cc1)NC=CNCCOC(c1ccc(F)cc1)c1ccc(F)cc1 +CC(F)(F)C(=O)Nc1ccc(F)c(C2(C)CS(=O)(=O)C3(CCOC3)C(=N)N2)c1 +CCc1ccc2ncc(C(=O)OCC(C)CC)c(O)c2c1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)C4CCC(C)N4CC(C)C)ncn3)cccc2s1 +COCCN(C)c1ncc2ncnc(Nc3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3F)c2n1 +OC1CCC(Nc2cc(-c3cncc(NCC4CCCOC4)n3)c(Cl)cn2)CC1 +CN1CCN(c2nc(-c3ccccc3)c(-c3nc4ccccc4c(=O)n3-c3ccccc3[N+](=O)[O-])s2)CC1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(Cc3cc(F)cc(F)c3)CC2)C1 +COc1c(Br)cc(Br)cc1CNC1CCCN(c2nc3nc(Cl)ccc3[nH]2)C1 +O=C(c1c[nH]c2cc(F)ccc12)C1CSC(c2cccnc2)N1 +Cn1ncc2ccc(-c3cc(COCC(O)CN4CCc5ccccc5C4)on3)cc21 +CCN(CC)C(=O)c1ccc(-c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)cc1 +CNC(=O)CN1Cc2ccccc2N(C2CCN(C3CCCCCCCCC3)CC2)S1(=O)=O +O=S(=O)(Nc1nccs1)c1ccc(NC(=S)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)cc1 +Cc1nc(N(C)C)ccc1N1CCc2c(-n3ccc(-c4nccs4)n3)ccnc21 +COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2cccc(C)c2)CC1 +CN1C(=O)C(NC(=O)Nc2cccc(Br)c2)N=C(c2ccccc2)c2ccccc21 +Cc1ccc(-c2nc(C)c(C(=O)NC3CCCN(c4cccc(C(=O)O)c4)C3)s2)cc1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 +C#CCOC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccccc3N3CCC(O)CC3)CC2)nn1 +O=C(c1cccs1)c1no[n+]([O-])c1C(=O)c1cccs1 +CC1=NN(C)C2C(=O)N(c3ccc(=O)n(C)c3)C(c3ccc(Cl)cc3)C12 +COc1cc(C(=O)Nc2cc(C3CC3)ccn2)ccc1-c1nc(C2CCC3C(C)OC(=O)N3C2)n2ccnc(N)c12 +NS(=O)(=O)c1ccc(-c2cn(-c3cccc(Br)c3)nn2)s1 +CS(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CCCCC3)cc2C(N)=O)cc1 +COC1CCC2(CC1)Cc1ccc(C#N)cc1C21N=C(C)C(N)=N1 +O=C(Nc1ccc(Cl)c(Cl)c1)c1ccc2cn[nH]c2c1 +CC(C)OCC#Cc1cc2c(cc1N1CCN(C3COC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CNCCn1c(=O)n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c2ccccc21 +Cn1c(-c2ccc(-n3ccnc3)cc2)nnc1C1(c2ccc(Cl)cc2)CCC1 +COc1ncnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +CC(C)CN1CCC23c4c5ccc(O)c4OC2c2[nH]c4ccccc4c2CC3(O)C1C5 +CC1=CC(C)(C)Nc2cc3c(cc21)-c1ccc(F)cc1C3O +CCC(C)C(NC(=O)C(CC(C)C)C(C(C)C)N(O)C=O)C(=O)Nc1ccccn1 +C#CCn1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 +CS(=O)(=O)N1CCN(C2CCC(Nc3ncnc4ccc(C#N)cc34)CC2)CC1 +COc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3ccnn3)c1)=N2 +Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3Cn3cccc(C(F)(F)F)c3=O)c2n1 +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)c(N)c1N +CCN(C(=O)c1ccc(F)cc1)C1CCN(C(C)CC(NC(=O)C2CCC2)c2ccccc2)CC1 +CC1CC(=O)NN=C1c1ccc2nc(-c3ccsc3)oc2c1 +Cc1ccc(N(C(=O)c2cc(F)cc(F)c2)C(=S)OCCN2C(=O)c3ccccc3C2=O)cc1 +C(=Cc1ccccc1)CN1CCN(C(c2ccccc2)c2ccccc2)CC1 +CC1OC(=O)C2CC3CC(F)(F)CCC3C(C=Cc3ccc(-c4ccccc4Cl)cn3)C12 +CC(=O)NC(Cc1ccc(OP(=O)(O)O)cc1)C(=O)NC1CSCCN(Cc2cccc(-c3ccccc3C#N)c2)C1=O +CC1(O)CCN(c2cccc(C(=O)NC3C4CC5CC3CC(O)(C5)C4)n2)CC1 +CCC(CC)C(=O)Oc1cn(-c2ccccc2)c(CSc2nc3ccccc3s2)cc1=O +O=C1N=C(Nc2ccccc2)N=C2C1N=CN2C1CC(O)C(CO)O1 +CCOc1cccc(NC(=O)C2Cc3cc(OC)c(OC)cc3C2=O)c1 +COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cnc2O)C3=O)c(OC)n1 +CN(C(=O)Oc1ccc(F)cc1)C1(C)CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)CC1c1ccc(Cl)cc1 +N#Cc1cnc(-c2nc(CC(=O)N3CCC3)cs2)c(O)c1 +COC1COC2C(OC(=O)NC(Cc3ccccc3)C(O)CN(CC(C)C)S(=O)(=O)c3ccc(N)cc3)COC12 +CC(=O)NC(C)c1ccc(C2CN(c3ccc4c(c3)OCCO4)C2)cc1 +Cc1c(-c2ccccc2F)c(=O)n(CC(N)c2ccccc2)c(=O)n1C1CCCCC1 +COc1cc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)oc3c2)ccn1 +CN1CCN(CCCNc2ccc(-c3cc4ncn(C)c(=O)c4c(NC4CC4)n3)cc2S(C)(=O)=O)CC1 +COc1cc(-c2cnn(CCN(C)C)c2)ccc1Nc1ncc2ccnc(NC3CCCCC3)c2n1 +COc1ccc(-n2c(C)nnc2N2CCC(Oc3ccc(F)cc3C)C2)cn1 +CCN(CC)CCNC(=O)c1ccc(Nc2ncc(C)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +CN(CCO)Cc1ccc(-c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)cc1 +Cc1cc(OCc2ccc(Cl)c(Cl)c2)ccc1CN1CC(C(=O)O)C1 +CN1CCCC1CCN1CCOc2cc(N=C(N)c3cccs3)ccc21 +O=C(CC1(N2CCOCC2)CCCCC1)Nc1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1 +COc1ccc(N2CCN(CCCOc3ccc(=O)n(-c4ccc(Cl)c(Cl)c4)n3)CC2)cc1 +O=C(CCCCCCCCc1ccccc1)c1nnc(-c2ccccn2)o1 +CCN(CC)Cc1cc(F)ccc1C=C1Oc2ccc(O)c(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +CCNC1=NC(=Cc2ccc(-n3cnc(C)c3)c(OC)c2)C(=O)N1Cc1ccc(F)cc1 +CC12CCC3C(=CCc4cc(O)ccc43)C1CCC2=O +CC(C)(C)C(NC(=O)OC1CCCC1)C(=O)N1CC(Oc2nccc3ccccc23)CC1C(=O)NC1CCCOB1O +CCCn1c(=O)c2[nH]c(-c3ccc(N)cc3)cc2n(CCC)c1=O +COc1ccc(S(=O)(=O)N(CCn2cccc2)C(Cc2cccs2)C(=O)NO)cc1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]c(-c4ccc(Cl)c(Cl)c4)nc3c2)c1F +COc1cc2c(cc1OC)C(=O)C(C(=O)Nc1ccc(Cl)cc1)C2 +O=C(O)CCc1sc(C=C2NC(=O)CS2)nc1-c1ccccc1 +O=C(O)C(Cc1ccc2c(c1)oc1ccccc12)NC(CCc1cccc2ccccc12)P(=O)(O)O +O=S(=O)(c1cccc2ccccc12)N(CCCN1CCN(c2ccccc2)CC1)CC1CC1 +CC(NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CN(C(=O)CC(N)=O)CC2=Cc1ccc(F)cc1)c1ccccn1 +CCCCc1nc(SCCCCO)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 +COc1ccc2nccc(NC(=O)C3CCC(NCc4cc5c(cn4)OCCO5)CO3)c2n1 +CS(=O)(=O)c1ccc(-c2cnc3ccc(-c4cccc(C(=O)NCCO)c4)nn23)cc1 +N=C(N)NCCCC1NC(CNC(=O)C2CCc3ccccc3C2)CCN(CC(c2ccccc2)c2ccccc2)C1=O +Cn1cc(C(=O)OCC2CN(Cc3ccc(Cl)cc3)c3cn(CCc4ccccc4)nc3C(=O)N2)c2ccccc21 +CC(C(=O)OC1C[N+]2(CCCc3ccccc3)CCC1CC2)(c1ccccc1)N1CCCCC1 +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CCCC(C)(C)O)CC(O)C(CCn2ncnn2)C1O +CN1CC=C(c2c[nH]c3ccc(-c4cccs4)cc23)CC1 +CNC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1S)CC(C)C +Cc1cc(S(C)(=O)=O)cc2c(Nc3cccc(C#N)c3)c(C(N)=O)cnc12 +Cc1ccc2nc3ccc(N4CCCC4)nn3c(=O)c2c1 +Cc1cccc(N2CCN(CCCCCCN3CCN(c4ccccc4)CC3)CC2)n1 +CC(CNC(=O)c1cc(Cl)cc(Cl)c1)CNc1nc2ccccc2[nH]1 +CCCCN(c1cccc(-c2ccc(Cl)cc2)c1C)S(=O)(=O)c1ccc(OC(CCC)C(=O)O)c(C)c1C +CCN(CC)CCNC(=O)C=Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 +Cc1c(C(=O)Nc2ccc(C3CNCCO3)cc2)n[nH]c1-c1cccc(C#N)c1 +CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2(C#N)C3CC4CC(C3)CC2C4)cc1F +CCCC(NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)P(=O)(O)O +CC(=O)N(Cc1ccc(F)cc1)C1=C(NCc2ccccc2)C(=O)c2ccccc2C1=O +O=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1cccc(CCn2cccc2)c1 +c1cnc(C2CN(c3nnc(N4CCC(N5CCCCC5)CC4)s3)CCO2)cn1 +Cc1ccccc1Nc1cc[nH]c(=O)c1C(=O)Nc1ccc(N2CCN(C)CC2)cc1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccccc1 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+O=C(Nc1ccc(Br)cc1)N1CCN(CC2CCCN(C3CC3)C2)CC1 +COc1ccccc1N1CCN(CCNC(=O)C2CCCCC2)CC1 +Cc1c(O)cccc1C(=O)NC(Cc1ccccc1)C(O)C(=O)N1CSC(C)(C)C1C(=O)NC1CCCC1 +CC1Cc2nc(NCC(F)F)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2CN1C +CC(C=CCN1CCCC(CCC2CCNCC2)C1=O)CC(=O)O +Cc1nn(C(=O)C=Cc2cccc(C(F)(F)F)c2)c2c1C1C(C2)C1(C)C +C=CCN(C(=O)OCc1ccc(F)cc1)C1CCN(CC2CN(C(=O)C3CCCC3)CC2(O)c2ccccc2)CC1 +CN1CC(n2nccc2-c2cc(C(F)(F)F)ccc2-c2cccc3cc(S(=O)(=O)Nc4nccs4)ccc23)C1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cc5ccccc5F)C4)cc23)ccn1 +CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)c3c2C(=O)N(c2cccnc2)C3=O)cc1 +CCNC(=O)c1cccc(-n2ccc3cnc(Nc4cc(OC)c(OC)c(OC)c4)nc32)c1 +O=C(O)Cc1nn(Cc2nc3cc(F)cc(Cl)c3s2)c(=O)c2ccccc12 +Nc1ccncc1-c1cc(F)cc(-n2nnc(-c3ccccn3)n2)c1 +C[N+](C)(C)CC1CSC(C2CCCCC2)(C2CCCCC2)O1 +N#Cc1ccc(F)c([S+]([O-])c2nc(-c3cnn4ccc(Br)cc34)cs2)c1 +Cc1ccc(-c2cn(C)c(CCc3nc4c(F)cccn4n3)n2)o1 +NC1=NC2(CCS1)c1cc(NC(=O)c3ccc(F)cn3)ccc1Oc1c2cc(-c2ccnc(F)c2)nc1F +O=C(NC(CC1CCCCC1)C(=O)NCCNc1ccc(OC(F)(F)F)cc1)c1ccc(-c2cccc(C(F)(F)F)c2)o1 +CCN1CC(C)(C)Oc2nc(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)NC)cc3F)c2C1=O +O=C(NC1CCCCC1O)C1Cc2c(sc3ccccc23)CN1 +Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3)ccc12 +COc1ccc(-c2nncn2-c2cc(OC)c(OC)c(OC)c2)cc1N +CN1C(=O)NC(=O)C12Cc1cc3nc(Cn4c(=O)n(-c5ccccn5)c5ccccc54)[nH]c3cc1C2 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCNC2 +Cc1nc2cc(F)c(Cn3c(C(=O)O)c(-c4ccc[nH]c4=O)c4c5occc5c(F)cc43)cc2c(=O)[nH]1 +NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1cccnc1N1CCC(c2ccccc2)C1 +O=C(Cc1ccc2c(c1)OCO2)NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1 +Cn1cc(-c2ccccc2Oc2ccccc2)c2cc(-c3ccccc3)[nH]c2c1=O +COCCOc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C)n1 +CCOc1ccc(S(=O)(=O)N(CC(=O)N2Cc3ccccc3CC2CC(N)=O)c2ccc(C)cc2)cc1 +N=C(N)C1(C(=O)Nc2ccc(CCCCCCOCC3CCCCC3)cc2)CC1 +NC1=NC(=O)C2CCCN2c2ccc(cc2)OCC=CCNCC(=O)Nc2c(Cl)cc(cc2Cl)CN1 +CCCCC(=O)NCC1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +CN(C)CCOc1ccc(-c2cccc(N)n2)c2c1CCC2 +Cn1cnc2c(-c3ccc(OCCC4CCN(CC#N)CC4)c(C(F)(F)F)c3)nc(C#N)nc21 +O=C1NCc2ccc(OCCCCN3CCN(c4cccc5ccc(F)cc45)CC3)c(F)c21 +CCC(C(=O)OCC1(CO)CC(=Cc2ccccc2C(F)(F)F)C(=O)O1)c1ccccc1 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)Nc3ccc(N)cc3)CCC12 +CC1(C)C2CCC(NC(=O)c3cc(Oc4c(Cl)cc(-n5ncc(=O)[nH]c5=O)cc4Cl)ccc3O)C1C2 +Cc1cc2nc(-c3ccc(-n4nc5c(c4C)N(C)S(=O)(=O)c4ccccc4-5)cc3)[nH]c2cc1C +CC(=O)Nc1ccc(-c2nc(Nc3ccc(N4CCOCC4)cc3)ncc2C)cc1 +CCOC(=O)c1nn2c(=O)[nH]c3cc(Cl)c(NC(=O)c4ccccc4C(=O)O)cc3c2c1C(=O)OCC +COc1ccc2c(c1)C1(CC(N)=O)CCN(CC3CC3)C(C2)C1CO +COc1ccc(C(=O)NN=C(C)C(=NNc2ccc(S(N)(=O)=O)cc2)S(=O)(=O)c2ccccc2)cc1 +CC(O)c1cc2cnc(Nc3cc(C(=O)N4CCN(C)CC4)n(C)c3)nc2n1C1CCCC1 +CN1CCN(Cc2ccc(C(=O)NN(Cc3ccco3)c3nc(C#N)ncc3Br)cc2)CC1 +O=C1CCN(C(=O)CCSc2ccc([N+](=O)[O-])c3nonc23)CC1 +COC1=CC(=O)c2c(c(COC(N)=O)c(C)n2C)C1=O +Cc1nc2ccccc2c(Nc2ccc(N3CCN4CCCCC4C3)cc2)c1C +O=C(O)C(Cc1ccccc1)NC(=O)C1CCC(=O)N1Cc1ccccc1 +Cc1cc(-c2cccc3ncc(-c4ccc(C(=O)N5CCOCC5)c(C)c4)nc23)ccc1CN1CCOCC1 +O=S(=O)(c1ccc(Cl)cc1)C1(c2cc(F)ccc2F)CCCC(CCCO)C1 +C=C(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc2cc(C(=O)O)ccc2c1 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+CC1=C2NCC3C(CCC4(C)C(C(=O)Nc5c(C(C)(C)C)cccc5C(F)(F)F)CCC34)C2(C)CCC1=O +COc1ccc(Br)cc1CCc1c(Cl)cccc1C(=O)N=C(N)N +NC(CC(=O)NC1(c2nc3c(Cl)cccc3s2)CCS(=O)(=O)CC1)Cc1ccccc1F +O=C(c1ccc(Cl)cc1)N(c1ccccc1)C1CCN(Cc2ccccc2)CC1 +O=C(O)c1ccccc1-c1ccc(Cn2c(C3CC3)nc3c(CO)ccnc32)cc1 +COc1ccc(-c2cnc3c(-c4cccnc4)cnn3c2)cc1 +O=C1CCc2cc(C(c3ccncc3)C3CCCCC3)cc3c2N1CC3 +CC1(c2cccc(-c3cncnc3)c2)N=C(N)c2ccccc2S1 +O=C1NC(=O)C(c2cc(Cl)ccc2S(=O)(=O)NCCCc2ccccc2)N1 +Cc1ccc(-c2c(C(=O)CCl)n(CCCO)c3ncnc(N)c23)cc1 +CC(C)(C)COP(=O)(CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)OCC(C)(C)C +Nc1n[nH]c2cc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccc12 +Cn1ncc(-c2ccc3c(c2)N(c2nc4c(s2)C(=O)NC(C)(C)C4)CCO3)c1N +CCN(C)C1CN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)C1 +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2CC2CCCCC2)cc1 +COc1ccc(OC)c(C=CC(=O)c2ccccc2-c2ccc(F)cc2)c1 +CC(c1ccc(-c2cc[nH]c(=O)c2)cc1)N1CCC(CC(C)(C)C#N)(c2ccccc2)OC1=O +NCC(c1ccccc1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1 +O=C(Nc1cccc(NC(=O)c2ccco2)c1)c1ccccc1 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+Clc1ccc(C2CC3CCC2N3CCCCCCN2C3CCC2C(c2ccc(Cl)nc2)C3)cn1 +CN1CCCC1c1ccc(C(O)(c2ccccc2)c2ccccc2)o1 +N#Cc1cc2cn(S(=O)(=O)c3cccc4ccccc34)c3cccc(o1)c23 +COc1cc(OC)cc(N(CCN(Cc2ccc(N)cc2)C(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1cc(Nc2nc(N3CCN(C(=O)Cc4ccccc4C)CC3)nn3cccc23)n[nH]1 +O=C(O)CCCCCCCOc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1 +NC(=O)c1cccnc1COc1cc(-c2ccc3c(c2)COC(=O)N3)cc2ncccc12 +CNc1nc(CC(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cs1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(Cl)nc1 +COc1cc(C)nc(OC(C(=O)O)C(OC)(c2ccccc2)c2ccccc2)n1 +CCCCC1CC(N(C)C(C)C)CCC1NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCC(N)C4)ncn3)c2c1 +Cc1cc(Nc2ncc(-c3nc4ccncc4s3)c(NC3CC(CO)C(O)C3O)n2)ccn1 +CN1CCN(CC=Cc2ccc3c(c2)CC2CCC(C3)C23CN(CC(F)(F)F)S(=O)(=O)N3)CC1=O +CCN1CCN(C(=O)NC(C(=O)NCB(O)O)c2ccc(O)cc2)C(=O)C1=O +Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1Cc2ccccc2C1 +O=C(NCCCCO)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +CCOc1cc(C(Nc2ccc3cnccc3c2)C(=O)NS(=O)(=O)c2cccc(S(C)(=O)=O)c2)ccc1OC(C)C +C=C(Br)C(=O)Nc1cccc(C=CC(=O)Nc2cc(OC)c(OC)c(OC)c2)c1 +CCCC(C)CN1CCC(c2ccc(C(O)(CC)CC)cc2)(c2cccc(C(N)=O)c2)CC1 +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(N)=O)c12 +CC1CCC(C)N1CCCOc1ccc(-c2ccc(C#N)cc2)cc1 +COc1ncc(N2CCc3ncnc(NC4CCN(C(=O)c5cn(C)cn5)C4)c3C2)cc1C +Cc1cccc(S(=O)(=O)NC(=O)NCCCCCCCCNC(=O)NS(=O)(=O)c2cccc(C)c2)c1 +CCNC(=O)Nc1ccc(CCCCNCCc2c(-c3cc(C)cc(C)c3)[nH]c3ccccc23)cc1 +COc1cc2ncc(C#N)c(Nc3ccc(Cl)c(Cl)c3)c2cc1OC +COc1c(F)cccc1C(=O)N1CCCC(Nc2nc3cc(Cl)ccc3o2)C1C +CNC(C)C(=O)NC(CCC(N)=O)C(=O)N1CCCC1C(=O)NC1CCCc2ccccc21 +O=S(=O)(c1ccccc1)N(c1ccc(O)cc1)c1ccc(OCCN2CCCCC2)cc1 +O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1ccc(Cl)cc1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2ccc(F)cc2F)c1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4cc5ccccc5cn4)CC3)CN(C)C1C2 +O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OC2C3CC4CC2CC(F)(C4)C3)cc1F +CCOC(=O)c1c(NCCNc2ccccc2)n(-c2ccccc2)c(=S)n(-c2ccccc2)c1=O +CCn1c(-c2nonc2N)nc2cncc(OC3CCNCC3)c21 +Cc1cc2c(-c3ccc(NS(=O)(=O)CCN)cc3)ccnc2[nH]1 +COc1cc(NC(=O)NCc2ccc(C=CC(=O)NO)cc2)ccc1-c1cnco1 +COc1ccc2ncc(-c3cccc(C(F)(F)F)c3)n2n1 +Cc1nc(C(C)(C)NC(=O)c2ccc(C3CCOCC3)c(OCC3CC3)n2)no1 +O=C(Nc1cccc(Cl)c1)NC1C(=O)N(c2ccccc2)c2ccccc2N(C2CC3CCC2C3)C1=O +COC(=O)c1[nH]c(C(C)(C)C)cc1NC(=O)Nc1ccc(Cl)cc1 +CN(C1(C(=O)O)CCCC1)S(=O)(=O)c1ccc2c(Cl)cnc(N=C(N)N)c2c1 +O=C(C=CC#Cc1ccccc1F)NC1=C(C(=O)O)CCCC1 +N#Cc1cccc(S(=O)(=O)c2sc3ncccc3c2-c2ccc(Cl)cc2)c1 +CC(C)n1c(=O)n(C(=O)NCCN2CCNCC2)c2ccccc21 +O=C(NCc1ccc(OCC(F)(F)F)cc1)C1c2ccccc2C(=O)N1CCc1ccccn1 +Cc1ccc(C=CC(=O)Nc2ccc3nc(N4CCN(C)CC4)cc(C)c3c2)cc1 +Nc1ccc(CC(=O)Nc2n[nH]c3ccc(N4CCCS4(=O)=O)cc23)cc1 +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)c1ccccc1C(=O)N2C +COc1cc(-c2nc3ccc(Cl)cn3c2NC2CCCCC2)ccc1OCCCNC(=O)Nc1ccc(OC(F)(F)F)cc1 +O=C(CC[n+]1cccc(F)c1)Nc1ccc2nc3c4[nH]c5ccccc5c4ccn3c(=O)c2c1 +COc1ccccc1N1CCN(CCCCCc2cn(-c3ccc(-c4ccsc4)cc3)nn2)CC1 +Cc1ccccc1CN1C(=O)CCc2cc3cc(c21)OCC=CCOC1CC(CO)N(C1)c1cc(n2ncc(Cl)c2n1)N3 +CN1C(=O)C2(N=C1N)c1cc(-c3cccnc3F)ccc1OC1CCCOC12 +O=C(O)C1=C(C(=O)Nc2c(F)cc(-c3cccc(OC(F)(F)F)c3)cc2F)COC1 +COc1ccc(-c2cnnn2-c2cc(OC)c(OC)c(OC)c2)c(O)c1 +NCCCNCCCCNCCCNC(=O)C(Cc1ccc(O)cc1)NC(=O)CC1CCCCC1 +Fc1cnc(OC2CN(c3ccc4ccccc4n3)C2)c(N2CCC(F)(F)CC2)c1 +O=C(Nc1n[nH]c2cc(-c3ccc(O)cc3)ccc12)c1ccc(OCCN2CCCCC2)cc1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(OCC4CCCO4)cc3)ncc2F)c1 +O=C(CSc1nc2ccccc2c(=O)n1C1CC1)c1cccs1 +O=C(O)CCc1ccccc1CC1=C(c2nc(C(=O)NCCc3ccc(Cl)cc3)co2)CCCC1 +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccco1 +CCOC(=O)N1CCC(N(C(=O)c2ccc(-c3cnco3)cc2)C2CC2)CC1 +Cc1nc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1 +CN1CCN(c2ccc([N+](=O)[O-])c(N3CCCCC3)c2)CC1 +CC(C)CN(NC(=O)OC(C)(C)C)c1nc(C#N)ncc1Cl +Cc1cncc(C2=CCC3C4CC=C5CC(NC(=O)C6CC6)CCC5(C)C4CCC23C)c1 +CNC(=O)c1cc2c(Oc3ccc(-n4cncn4)cc3)cncc2s1 +CC(CCc1ccc(OCc2c(F)cc(F)cc2F)cc1)(C(=O)NO)S(C)(=O)=O +C=S(C)(=O)NC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4cccc(C)c4)cc3)ccn2)c1 +Fc1ccc(-c2[nH]cc(C3=CC4CCCCN4CC3)c2-c2ccncc2)cc1 +CN1C(=O)NC(=O)C1=Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 +COc1cc2nc(N(C)C(C)C)nc(NC3CCN(C)CC3)c2cc1OC +O=C(Nc1cccc(OCC(O)CN2CCc3ccccc3C2)c1)c1cnccn1 +COc1ccc(C(=O)N2CC(Oc3nccc(C#N)c3C)CCC2C)c(C2CC2)n1 +CNC(=O)CCn1ncc2cc(Nc3ncc(F)c(Nc4ccc5c(c4)OCCO5)n3)ccc21 +COC(=O)N1Cc2[nH]c(-c3cc(C(=O)N4CCC(c5ccc(C#N)cc5)CC4)c(C)cc3C)nc2CC1C +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc(C(=O)c3ccccc3F)c2)[nH]c1=O +O=S(=O)(c1ccccc1)C1(c2cc(F)ccc2F)CCCCC1 +COc1ccccc1-c1c(C(N)=O)sc2cnc(Nc3cc4c(cc3OC(C)C)N(C)C(=O)CCC4)nc12 +Cc1cc(-n2ccc(N3CCNC3=O)n2)c2c(n1)N(c1ccc(C#N)cc1OC(F)(F)F)CC2 +COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +CCN1CCN(c2ccc(Nc3nccc(-c4sc(NC5CCCC5)nc4C)n3)nc2)CC1 +CCC(C)C1=NC2CCC34CC35C(=O)CC3(C)C(C(C)N(C)C)C(O)CC3(C)C5CCC4C2(C)CN1 +COc1ccc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(C(F)(F)F)nc12 +CC(C)c1ccc2nc3ccc(C(O)=NCCCCc4ccncc4)cn3c(=O)c2c1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(CC(=O)O)cnc3ccccc23)cc1 +COc1cc(OC)cc(N(CC(C)NC(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CC(C)CNc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +CCOC(C)OC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +CC(CO)NC(=O)CCCC=CCC=CCC=CCC=CCCCCc1ccccc1Br +O=C(CCC(=O)Nc1nc(-c2ccccc2)cs1)NCCCCNc1c2c(nc3ccccc13)CCCC2 +COc1cc(F)cc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(OC(F)(F)F)c2)c1 +O=S(=O)(c1ccc2[nH]ccc2c1)c1cc(Cl)c2oc3c(c2c1)CNCC3 +CCCCOc1ccc2c(C#N)cn(-c3ccc(C(=O)O)c(O)c3)c2c1 +Cc1cccc(NC(=O)Nc2cccc(C#Cc3cncc(C(=O)N=S(C)(C)=O)c3)c2)c1 +O=C(c1ccc(OCCCCc2c[nH]cn2)cc1)C1CC1 +CC(=O)N(O)C(c1ccc(OCCc2ccccc2)cc1)C(C)C +CNC(=O)CN1N=C(c2ccccc2)C2(CCN(C3CCC(C(C)C)CC3)CC2)C1=O +CN(CCc1ccccc1)C1CCC(c2c[nH]c3ccc(C#N)cc23)C1 +Cc1ccc2c(c1)C(=O)N(C(C)COC(=S)Nc1ccc(Cl)cc1)C2=O +CN=C(N)c1ccc(C(=O)N2CCN(S(=O)(=O)c3ccc4cc(Br)ccc4c3)CC2)cc1 +CCCc1nn(C)c2c(=O)nc(-c3cc(S(=O)(=O)N4CCN(CC)CC4)ccc3OCC)[nH]c12 +CC(C)(C)Cc1cnc(CCc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 +COc1cc(OC)c(N(C)C(=O)c2cc3c(s2)-c2ccccc2S(=O)(=O)C3)cc1Cl +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4cc(C)ccc4[nH]3)CC3CC123 +c1ccc2c(N3CCN(CCc4ccc5[nH]nnc5c4)CC3)cccc2c1 +CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCN(Cc3ccccc3F)C2=O)CC1 +CC1CN(c2nc(N3CCOCC3C)c3ccc(-c4ccc([N+](=O)[O-])cc4)nc3n2)CC(C)O1 +COc1cccc2cc(C(=O)NCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)oc12 +CCC1OC(O)=C2C1=NC1=C(C(=O)OC1)C2c1ccc(F)c(Br)c1 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccccc3O)cc12 +Cc1cc(COc2ccc(S(=O)(=O)CC3(CC(=O)NO)CCCNC3)cc2)c2ccccc2n1 +Cc1nn(-c2ccc(C#N)c(C(F)(F)F)c2)c(C)c1Cc1ccc(F)cc1 +CCC1CCCC(C2(OC(=O)N3CCN(C(C)(C)CO)CC3)CC2)N1S(=O)(=O)c1cc(F)cc(F)c1 +O=C(CCl)Nc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCOCC1 +CC(C)(C)c1ccc(N2CCN(Cc3ccc4ccc(=O)oc4c3)CC2)cc1 +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCCC(N)C(=O)O +CC1(C)OCc2c(Nc3n[nH]c4c(Cl)cccc34)nc(-c3cn[nH]c3)nc21 +COCCN1CCN(c2ncc3ncnc(Nc4cc(C(=O)Nc5ccc(C#N)c(C(F)(F)F)c5)ccc4C)c3n2)CC1 +CC1(C)CCN(C2C3CC4CC2CC(O)(C4)C3)C(=O)c2cnn(C3CCCCC3)c21 +Cc1cccc(C)c1-c1ccccc1CN(C(=O)c1ccc(-c2ccc(C#N)cc2)o1)c1ccc(N2CCNCC2)cc1 +CCC(=O)n1nc(-c2ccco2)nc1SCc1ccccc1 +O=C(NCC1CCN(CCCCCC(c2ccc(F)cc2)c2ccc(F)cc2)C1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1cc(Cl)nc(C)c1C(=O)NCCC(C)N1CCC(N(Cc2ccsc2)C(=O)NO)CC1 +CCN(CC)CCCC(C)Nc1c2ccccc2nc2ccccc12 +CCOc1cc(C2(C#N)CC3CC(C(=O)O)CC3C2)ccc1OC +CN(C)c1ccc2c3c1OC1C(O)C=CC4C(C2)N(C)CCC341 +COc1cc(N2CCOCC2)ccc1Nc1ncc2cccc(-c3ccccc3)c2n1 +O=C(O)CC1CCCc2c1n(Cc1cccc(OCCCC#Cc3cccnc3)c1)c1ccc(F)cc21 +CSc1ccccc1N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1 +Cc1ccc2[nH]c3c4c5ccccc5nc-4c[nH]c3c2c1 +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCN(C)CC5)sc34)cc2F)c1 +CCN(CC)C(=O)N1CCC(CCN2C3CCC2CC(n2c(C)nc4ccccc42)C3)(c2ccccc2)CC1 +CC1(C)Cc2n[nH]c(=O)c3cccc4c3c2c(n4CCN2CCCC2)C1 +CN1CCN(c2nc(NCCS(=O)(=O)Nc3ccccc3)c3ccc(Cl)c(Cl)c3n2)CC1 +CC12C=CC(=O)C=C1CCC1C2CCC2(C)C(=O)OCC12 +Cn1cnc(-c2cccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)c2)c1-c1cc2c(N)ncnc2s1 +Cc1ccc2c(c1)C(=O)N(CCCCN1CCC(n3c(=O)oc4ccccc43)CC1)S2(=O)=O +CC(Nc1c(F)ccc(OCC(=O)O)c1F)c1cc(-c2cccc(F)c2)ccc1F +CCC(CO)Nc1nc(N2CCOCC2)[nH]c(=O)c1-c1nc2ccccc2s1 +NC(=S)N1N=C(c2cccc(Br)c2)CC1c1cccc(Cl)c1Cl +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(NC(=O)Nc3ccc4ccsc4c3)CCc3ccccc32)c1 +Cc1cn(-c2ccc3n(c2=O)CCN(C2CCC2Oc2ccc(Cl)c(C(C)C)c2)C3=O)cn1 +O=C(Nc1ccc(F)cc1C(F)(F)F)c1cc[nH]n1 +COc1cc(C)c2nc3[nH]nc(C)c3c(N3CCC(O)CC3)c2c1 +CN(C)CCN1C(=O)c2cccc3cc4nc(Cl)sc4c(c23)C1=O +C#CCNCC(=C)c1cccc(OCc2cccc(F)c2)c1 +CNc1nc(Cl)c(Cl)c(N2CCN(CCC3CCC(NC(=O)N4CCOCC4)CC3)CC2)n1 +CN(Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)COc1ccc(Cl)cc1)CC2)c1ccc(Cl)cc1 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cc(C)cc(C)c3)c(F)c2)CC1 +CN(CCN1CCCCC1)C(=O)C1CCC2(CC1)OC(=O)c1ccccc12 +O=C(Oc1cc2oc(=O)c3c(c2cc1Cl)CCCC3)c1cccs1 +COc1ccc(Nc2nc(-c3ccc(C(N)=O)cc3C)cn3ccnc23)cc1OC +Nc1ncc(-c2ccc(-c3ccccc3C(=O)N3CCOCC3)cc2F)cn1 +CCCN1CC(c2ccccc2)N(C2CCN(C(C)CCNC(=O)c3c(C)cc(Cl)nc3C)CC2)C1=O +Cn1ncc(NC(=O)c2nc(C3=CCCC3)sc2N)c1C1CCC(N)C(F)CO1 +CCCCCCCCOc1ccc(C=CC(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +COCCN(CCOC)c1nc(C)nc(Nc2c(C)cc(C)cc2C)c1SC +N#CCCNC1CCC(=CCn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +CC(C)(CC(O)(Cc1cc2ccccc2[nH]1)C(F)(F)F)c1cc(F)cc2c1OCC2 +CC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Cl)cnc32)CC1 +CN(C)c1ccc(C(=O)O)c(Oc2nc(Oc3cccc(-c4cccc(CN)c4)c3)c(F)c(N3CCNCC3)c2F)c1 +Cn1ccc(CNC(=O)c2ccc(NC(=O)N3Cc4cccnc4C3)cc2)n1 +Cc1ccnc(Oc2ccc(-c3cc4c(cc3F)ncc3nc(C)n(C5CCN(C(N)=O)CC5)c34)c(F)c2)n1 +CCC(CC)CN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +CN1CCN(c2cc(C(F)(F)F)nc(N3CCCC(C(=O)NCCc4ccc(C#N)cc4)C3)n2)CC1 +COC(C(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)C(C)C)c1ccccc1 +COc1ccccc1Nc1nc(-c2ccc(-c3ccccc3)cc2)c(CC(=O)O)s1 +O=C(Nc1cc(C(F)(F)F)no1)NC12CC3CC(CC(C3)C1)C2 +COc1cc(OCCO)cc(N(CC2CC2)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1 +O=C(c1ccc(Cl)cc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncon2)c1 +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2ccccc2F)c(C)c1 +O=C(OCCCCN1CCC(OCc2ccccc2)CC1)c1ccc(F)cc1 +COc1ccc(C)n2nc(CCc3nc(-c4cccs4)cn3CCCC#N)nc12 +Cc1c(CC(=O)O)c2ccc(F)cn2c1Sc1ccc(S(C)(=O)=O)cc1F +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(CO)c3)n3c2CCOC(C)C3)cc(C)n1 +CC1CCCC(C)N1Cc1cc2c(N)nc(-c3ccc(C(F)F)o3)nc2s1 +O=C1Nc2cccc3c2C1(CCCCN1CCc2n[nH]cc2C1)CCC3 +NC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +CN(C)C(=O)c1ccc(N(CC2CCCC2)C(=O)c2ccc(O)cc2O)cc1 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(-c3ccccc3)cn2)cc1 +O=S(=O)(NCc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1cccc(F)c1 +NCCCn1nc(C2=C(c3cn(-c4csc5ccccc45)c4ccccc34)C(=O)NC2=O)c2ccccc21 +Clc1cc(Cl)cc(C2OC3(CCN(Cc4ccc(N5CCCC5)cn4)CC3)c3ccccc32)c1 +CCc1cc(C)c(-c2nnc(COC)[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +O=C(NC1CC(c2ccccc2)CCN(CC2CC2)C1=O)N1CCC(n2nc(-c3ccccc3)[nH]c2=O)CC1 +CC(CO)n1c(=O)n(C)c2cnc3ccc(-c4cnn(C)c4)nc3c21 +CON=C(c1ccc(CN2CCC3(CC2)OCc2cc(F)ncc23)cc1)c1ccc(F)c(F)c1 +O=C(C1CCCN(c2ccc3nc(C4(n5cc(F)cn5)CC4)[nH]c3n2)C1)N1CCCC1 +NS(=O)(=O)c1ccc(C2=C(c3ccc(C(F)(F)F)cc3)CCC2)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(C(C)(C)C)cc2)CC1 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-c3nnco3)ccc(F)c12 +CC(=O)Nc1c(Cl)cc(CNC(N)=NC(=O)C2CC(O)CN2c2ccccc2)cc1Cl +CC1=C(C(=O)OC2CCCC2)C(c2[nH]cnc2Cl)C(C(=O)OC2CCCC2)=C(C)N1 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CC(C)CC(C)C1 +Cc1ccc2nc(N(Cc3cccnc3)C(=O)CCc3ccccc3)sc2c1 +NS(=O)(=O)c1ccc(CN2C(=O)c3cc(Cl)c(Cl)cc3C2=O)cc1 +Cc1ncc(Nc2cncnc2)c(C(=O)Nc2cn(C)nc2C(=O)NCC(C)(C)O)n1 +CN1Cc2c(C3=CCN(C(=O)OC(C)(C)C)CC3)[nH]c3ncc(F)c(c23)-c2cc(F)ccc21 +CCN(CC)S(=O)(=O)NC(=NC(C)C)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +CCc1ccc(S(=O)(=O)Oc2ccc(Cn3ccnc3)cc2)cc1 +CC(C(=O)NC1C2CC3CC1CC(O)(C3)C2)N1CCc2ccc3c(c2CC1)OCO3 +CCCC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12 +CS(=O)(=O)c1ccc(-c2ccc3ncc(-c4ccc(C(F)(F)F)cc4)n3n2)cc1 +O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccsc4)c3)cccc12 +O=C(NC(CCCCCCSSc1ccccn1)C(=O)OCc1ccc([N+](=O)[O-])cc1)OCc1ccccc1 +CC1C2Cc3ccc(C(N)=O)c(N)c3C1(C)CCN2CC1CC1 +N#Cc1c(N)nc2sc(C(=O)c3cccc(Cl)c3)c(N)c2c1-c1ccccc1I +COc1ccc(C2CC2c2ccc(OC)c(OC)c2OC)cc1N +CCOC1(OCC)C2c3c(Br)cccc3C([n+]3ccccc32)C1(C)C +CN(C)C1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cn5ccc(C#N)cc5n4)c3)sc2C1 +CCCCCCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +O=c1cc(N2CCOCC2)nc(Cc2nc3c(F)cccc3o2)[nH]1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(N3CCOCC3)cc2n1Cc1ccccn1 +COc1ccc(C=CC(=O)N2CCN(C(=O)c3ccc(C)cc3)CC2)cc1 +COCCNC(=O)CCc1c(C)c2c(OC)cc(O)c(C=O)c2oc1=O +O=C(Nc1ccc(F)cc1)c1ccc(SCc2ccccc2)nc1 +Cc1ccccc1-n1c(Cn2nc(CF)c3c(N)ncnc32)cc2cccc(C)c2c1=O +CCCCCCCc1ccc(NC(P(=O)(O)O)P(=O)(O)O)cc1 +CCc1cc(C(=O)NC2CC(C(=O)NCc3ccc(C(F)(F)F)cc3)N(C(=O)c3coc4ccccc34)C2)n(C)n1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2cn3ccccc3n2)CC1 +COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)CNC(C)=O)C(C)C)C(C)C)ccc1OC +O=C(NC1CCCCC1C(=O)NC(CCc1ccccc1)C(=O)CO)OCc1ccccc1 +COc1ccc2c(c1)N(CCCCCC(=O)NO)C(=O)c1ccccc1S2 +O=C(O)CC(c1ccc(Cl)c(Cl)c1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)CC1CC1 +CC1CCC2C(C)C(OO)(C(F)(F)F)OC3OC4(C)CCC1C32OO4 +CCCN(CCc1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1)C1CCc2c(O)cccc2C1 +O=C(O)c1ccc2c(c1)nc(NCc1cccnc1)c1nc(NC3CC3)ncc12 +CC1COCCN1c1nc(N2CCN(C)CC2)nc2[nH]c(-c3cccc4[nH]ccc34)nc12 +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4cccnc4)cc3)nc2c1 +Clc1cccc(C(c2ccc(CN3CCCC3)cc2)(c2ccccn2)n2ccnc2)c1 +O=C1CC(c2c[nH]c3ccccc23)C(=O)N1CCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1 +COc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)c1F +Cc1cncc(-n2c(C(C)Nc3nc(N)nc(N)c3C#N)nc3cccc(Cl)c3c2=O)c1C +CC(OC1CC(C)N(C)C(=O)CC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(C(O)c1ccccc1)N(C)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)c(F)c2)c(F)c1 +C=CC(=O)Nc1ccc(CCn2c(=O)c(-c3cc(OC)cc(OC)c3Cl)cc3cnc(NCCN(CC)CC)nc32)cc1 +O=c1[nH]cnc2[nH]c(-c3ccnc(C=Cc4ccc(CN5CCOCC5)cc4)c3)cc12 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1ccc(Cl)cc1 +COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1 +NCCNC(=O)c1cc(N(CCCl)CCCl)c([N+](=O)[O-])cc1[N+](=O)[O-] +CCc1cc(C)c(-c2nc3c([nH]2)COCC3C)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +Cn1cnc2cc(-c3ccc(N)c(S(C)(=O)=O)c3)nc(NCCCO)c2c1=O +O=C1c2ccc(F)cc2C(=O)N1CCCCCN1CC=C(c2c[nH]c3ccccc23)CC1 +CCOC(=O)C(C)NP(=O)(OCC1OC(n2cnc3c(N)nc(NN)nc32)C(C)(O)C1O)Oc1ccccc1 +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CC(=O)O)CC(=O)O +O=C(NCC#Cc1ccc2ncnc(NC3CCOCC3)c2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +O=C(O)c1ccccc1Nc1ccnc(OCC2CCCCC2)n1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3CN(C)C)cc2F)n(-c2ccc3cc(Cl)ccc3c2)n1 +COc1cc(-c2nn(C3CCC(N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NCc1ccco1 +CC1(C#N)CCCC1Nc1c(C(N)=O)cnn2cc(-c3ccccc3)cc12 +NC(=O)c1cccc2[nH]c(C3CCC(=O)N3)nc12 +O=C(NCC1CCCC1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +C=CCN1C(=O)C(=Cc2ccc(O)c(Br)c2)SC1=S +O=C(O)C12CCN(c3nccc(-c4ccccc4OCc4ccc5c(c4)CCN(C4CCOCC4)C5)n3)CC1C2 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(C(=Cc2nn[nH]n2)c2ccccc2)cc1 +O=C1NC(=O)c2c1c1c3cc(Cl)ccc3[nH]c1c1cccn21 +CCN(CCCN1CCC2(CC1)OCc1ccccc12)C(=O)C(c1ccc(F)c(F)c1)N1CCCC1=O +COc1ccc(Nc2nnc(Cn3c(C)nc4ccccc43)s2)cc1 +COc1cc(CN2CC(C(=O)O)C2)ccc1OCc1ccccc1Cl +COc1cc2cc(NC(=O)c3ccc(O)c(CC=C(C)C)c3)c(=O)oc2c(C)c1OC1CCN(C)CC1 +Cc1ccc(COc2cc(F)c3nc(CC4(C(=O)O)CCCC4)n(Cc4ccc(C(F)(F)F)cc4)c3c2)nc1 +CN(C)c1ccc(NC(=O)NCCCCCCC(=O)NO)cc1 +CCN1C(=S)N2CCCC2c2c(N3CCOCC3)nc(-c3ccc(OC)cc3)nc21 +O=C(NC(Cc1ccc2nc(-c3ccncc3)ccc2c1)C(=O)O)c1c(Cl)cccc1Cl +NS(=O)(=O)c1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc1 +CN1CCCC(n2cc(S(=O)(=O)C3=C(Cl)NC4SC=CN34)c3cccnc32)C1 +COc1cc2c(NC3CCN(C(C)C)CC3)nc(C3CCCCC3)nc2cc1OCCCN1CCCCC1 +NCCCOc1cc2c(c(-c3ccc(Nc4nc5ccccc5o4)cc3)c1)CNC2=O +Nc1cnc(-c2ccc(C3CCC3)c(OCc3ccc(F)cc3)c2F)cn1 +CNc1cc(NC(=O)OC)ccc1Nc1c2ccccc2nc2c(Cl)cccc12 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1ccc(N2CC(O)C(O)C2)c(-c2ccn[nH]2)c1 +CCNC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)c1ccc2ccccc2n1 +O=C(Nc1cnc(-c2c(F)cncc2F)c(-c2cccnc2)n1)C1CC1 +CC(C)(N)C(=O)NC(CCCc1ccccc1)C(=O)N1CCN(c2ccccc2NS(=O)(=O)CC(=O)O)CC1 +COC(=O)C1=C(c2ccc(F)c(Cl)c2)CC2CCC1S2 +COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cn1)N(c1cc(Cl)ccc1C)C2=O +COc1ccc2c(c1)c(CCN(C)C)cn2S(=O)(=O)c1ccc(NC(C)=O)cc1 +CNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(CN5CCOCC5)c(C(F)(F)F)c4)ccc3C)CC2)ncn1 +CC(C)c1ccc(Cl)cc1-c1[nH]c(-c2ccnc(N)n2)cc1C(N)=O +CC(=O)NC(Cc1ccccc1)C(=O)CCC(=O)N1CCCC1C(=O)O +CCCNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O +CCNC(=O)C1OC(n2cnc3c(N)nc(C#CCN)nc32)C(O)C1O +CCN(CC)C(=O)NC1CCN(C(c2ccc(OC(C)C)cc2)c2cccnc2)CC1 +CCn1ncnc1C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 +NCCCCOCc1ccn2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c12 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccccc3)n(CC(=O)N3CCS(=O)(=O)CC3)c2c1 +O=C(NCCCNc1nc2cccc(Br)c2c2[nH]c3ccccc3c12)Nc1ccccc1 +CCCCCCCCCOc1ccc(NC(=O)ON=C(C)C)cc1 +COc1ccc(C(=O)N=C(Nc2cccc(C)c2)NC2CCCCN(CC(=O)N3CCCC3)C2=O)cc1 +COC(=O)C1CCN(Cc2ccc(OCCCN3CCN(c4ccc([N+](=O)[O-])cc4)CC3)cc2)CC1 +CC1CCc2nc(CCCCN3CCN(c4ccc5ccccc5n4)CC3)n(N)c(=O)c2C1 +CCn1ccc2ccc3c(c4c(c5c6ccccc6n(CCCO)c35)C(=O)NC4=O)c21 +CS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2)c(C(=O)N2Cc3cc(C(F)(F)F)cnc3C2)c1 +CC(=O)OC1OC(C)C2C(C=CC3CCCC(C)N3C)C3CCCCC3CC12 +CC1(C)OB(c2ccc(NC(S)=Nc3ccc(S(N)(=O)=O)cc3F)cc2)OC1(C)C +CC(C)N1CCN(c2ccc(Nc3ncc4cc(C(=O)N(C)C)n(C5CCCC5)c4n3)nc2)CC1 +COc1ccc(S(=O)(=O)N(Cc2ccc(F)c(F)c2)C(Cc2cccs2)C(=O)NO)cc1 +O=C(C=Cc1ccc(Cl)c(Cl)c1)N1CCC(C(CO)N2CCC(c3c[nH]c4ncccc34)CC2)CC1 +CC(C)Oc1cc(C(=O)O)cc(NC(=O)c2nc3c(s2)CN(C(C)C)CC3)c1CCC(=O)Nc1ccc(Cl)cc1 +Cc1cc(Cl)cc2c(C(O)c3ccccn3)c3c(C)n[nH]c3nc12 +NCC1OC(OC2C(N)CC(N)C(OC3OC(CSCCOCCS)C(O)C(N)C3O)C2O)C(N)CC1O +CC(C)CCn1cc(NC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cn1 +C[S+]([O-])CCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 +N=C(N)c1ccc(-c2ccc(-c3cn4c(n3)CCC(C(=N)N)C4)o2)cc1 +O=C(NC(CO)c1ccc(Cl)cc1Cl)C1CCc2ncsc21 +Cc1nc(N2CC3CN(C(=O)c4ccccc4-c4ncn(C)n4)CC3C2)nc(C)c1Cl +Cc1nc(C(=O)N2CCC2c2nc(-c3ccccc3OC(F)(F)F)no2)c(-c2ccccc2F)s1 +Cc1cccc(C)c1Oc1c(C(=O)N2CCNCC2)c2ncccc2n1-c1ccccc1 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4ccccn34)c12 +CSc1nccc(-c2c(-c3ccc(F)cc3)nc3nc(N)ccn23)n1 +CCCCCCCCCc1ccc(CN2CCC(P(=O)(O)O)C2)cc1 +Nc1nc2c(NCc3ccccc3)cccc2c2cn(-c3ccccc3)nc12 +O=C(NCCC1OCCO1)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +NC1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)CC1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1c2ccccc2CC1c1ccccc1 +COc1cnc(C(=O)Nc2ccc3c(c2)C2(CCOC(N)=N2)c2cc(C4CC4)ncc2O3)cn1 +Cc1nnc2sc(C(=O)NC3CN(c4ccccc4F)C3)c(N)c2c1C +COc1nc(NCCc2ccc3c(c2)OC(F)(F)O3)cc(-c2cccnc2)n1 +CC(C)(C)NC(=O)NCCN1CCN(CC(=O)Nc2cc(Cl)cc(Cl)c2)CC1 +O=C1Nc2cc(F)ccc2C1CCCCN1CCN(c2cccc(Cl)c2)CC1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCC(NCC(O)CO)CC3)cc12 +Cc1cccc(C(=O)c2cccc(C(=NNC(N)=S)c3cccc(C)c3)c2)c1 +CCOc1ccc(CC(NC(=O)c2ccncc2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)c(F)c2)cc1 +Cc1ccc(Cc2cc[n+](C)c(COc3ccc(C)cc3)c2)cc1 +CC(C)CN1CCC(S(=O)(=O)CCCOc2ccc3[nH]c4nc(O)nc-4cc3c2)CC1 +O=C(NC1CCCC(O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1CO +C=CC(=O)Nc1cnccc1Nc1nc(NC2CCOCC2)ncc1Cl +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cc1 +Cc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1 +Cc1cnc(Nc2ccc(C(=O)Nc3c(C)cccc3C)cc2)nc1-c1ccncc1 +CN(C)C(=O)C1CC1c1ccc(-c2nc(C3CC3)n(C)c2Sc2ccc(Cl)cn2)cc1 +O=C(Nc1ccncc1)C(=O)c1cn(-c2ccccc2)c2ccccc12 +COc1ccc(-c2c(-c3ccccc3)c3n(c2CC(=O)O)CC(C)(C)C3)cc1 +CN1CCN(C(CN2CCN(CCCCc3cccc4ccccc34)CC2)c2cccc(Br)c2)CC1 +COC(=O)C(Cc1cccc(C(=N)N)c1)C(C)NC(=O)c1ccc(-c2ccc[n+]([O-])c2)cc1 +CCCC1(CCC)CC(C(=O)NCc2ccc(C(=N)N)cc2)n2c1c(Cl)nc(NC1CCC1)c2=O +Cc1ccc(-c2ccc3ncc4[nH]c(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 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+COc1ccccc1Cn1ccc(C(=O)NCc2cn(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1=O +CC(=O)c1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1 +CCCC(NC(=O)c1cocn1)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 +CC(=O)c1ccc(NC(=O)CN2CCC(N3C(=O)OCc4cc(C)ccc43)CC2)cc1 +O=C1C(Nc2ccc(Br)cc2)=C(Cl)C(=O)c2ncncc21 +COc1cc(Nc2nc(-c3ccccc3)cs2)ccc1-c1cnco1 +Cc1cc(-c2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)ccn1 +CCCCCC(O)C=CC=CC=CC(O)CC=CCCCC(=O)NCCO +CN(C(=O)COc1cc(Cl)cc(Cl)c1)C1CCCCC1N1CCCCCC1 +CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cccc(C#N)c3)o2)c1 +Cc1ccnc2oc(-c3ccccc3Cl)cc(=NNC(=N)N)c12 +CSc1ccc2[nH]c3c([N+](=O)[O-])ccc4c3c(nn4CCCN(C)C)c2c1 +COc1ccc(C2=C(C(=O)c3ccc(OCCN4CCCC4)cc3)c3ccccc3CC2)cc1 +Cc1cc(C)cc(-c2[nH]c3ccccc3c2CCNCCCCCc2ccncc2)c1 +COc1cncc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC3)n2)n1 +CCN1CCC(=O)C(=Cc2c(C(F)(F)F)nn(-c3ccccc3)c2-c2ccc(Cl)cc2)C1 +COc1cnc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)COC3F)c2)cn1 +CCOC(=O)N1CCC(N2CCC2C(=O)N2CC(S(=O)(=O)c3cccc(Cl)c3)CC2C(=O)NC2(C#N)CC2)CC1 +COc1cc(NS(C)(=O)=O)cc(OC)c1Oc1ccc(C#N)c(Cl)c1 +CCc1nc(-c2ccc(Cl)cc2Cl)c(CC)nc1NC(COC)COC +Cn1cc(C(=O)C(=O)Nc2ccc(-n3cccc3)cc2)c2ccccc21 +CCc1nccn1CCCOc1ccc(-c2cccc(C#N)n2)cc1C(F)(F)F +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCCOC)CC2 +CCCN(c1ncccn1)C1CCN(CC2CN(C(CC3CCC3)C(=O)O)CC2c2cccc(F)c2)CC1 +COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C +CCC(C)c1ccc(N2CCN(CCn3c(=O)[nH]c4c([nH]c5ccccc54)c3=O)CC2)cc1 +CCC(C)CNC(=O)c1ccc(OC2CCN(CC3CCCCC3)CC2)c(Cl)c1 +O=C(O)C(Sc1nc(Cl)cc(Nc2ccc3c(c2)CCC3)n1)c1cccc2ccccc12 +CN(C)C1CCN(C(=O)c2nn(C)cc2NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)C1 +COc1ccccc1N1CCN(CCN=C(N)C2CCCCC2)CC1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCN(c3ccc(Cl)cc3)CC2)cc1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(Cl)cc1-c1ccnc(N2CCNCC2)n1 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(-c3ccco3)c(C(N)=O)c2)nc1 +O=C(O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3Cl)n3c2CCCC3)c(F)c1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(S(N)(=O)=O)cc3)CC2C(=O)O)nc2ccsc12 +CC1=Nc2ccc(Cl)cc2C(c2ccccc2)N1CCN1CCN(C(=O)c2ccco2)CC1 +Cc1nc2c(C(F)(F)F)cccn2c1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1 +O=C(O)C1CN(Cc2ccc(-c3cc4cc(Cc5ccccc5)ccc4o3)cc2F)C1 +COC1CCC2(CC1)Cc1ccc(-c3cncc(Br)c3)cc1C21N=C(C)C(N)=N1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCCCN(C)C13CC4CC(C)(CC(C)(C4)C1)C3)C2 +O=C(C1CC(Oc2ccccn2)CN1)N1CCCN(C2CCC2)CC1 +CN1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc21 +CC(C)c1nnc(C(=O)C(NC(=O)Cn2c(-c3ccc(F)cc3)ncc(N)c2=O)C(C)C)o1 +CCC1C(=O)CC2CCN(CC3CCCCC3)C3CCCC1C23 +CC(C)(COc1ccc(-c2ccc(-c3ncc(C(F)(F)C(F)(F)F)[nH]3)cn2)cc1)C(=O)O +COc1cccnc1-c1cccnc1Oc1ccc(Nc2nc3ccccc3s2)cc1 +CCN(CC)C(=O)c1ccc(C(c2ccccc2)N(C)CCNC)cc1 +O=C(NC1CC1)c1ccc(-c2cnc3c(SCCCCO)nc(-c4ccccc4)cn23)cc1 +CCC(Oc1ccc([Se]Cc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)cc1C)C(=O)O +CON(C)C(=O)N1N=C(c2cc(F)ccc2F)SC1(CCCN)c1ccccc1 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1n[nH]cc1Nc1nc(Cl)nc2ccccc12 +O=C(OCc1ccc(F)cc1)N1CCC(CNc2ncccn2)CC1 +Cc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(OCc3ncccc3C)nc1)CC2 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+CN(C)CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2sccc2Cl)CC3)n1 +O=C(Cc1ccccc1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 +CS(=O)(=O)c1cccc(-c2noc(-c3cnn(-c4ccccc4F)c3-c3ccncc3)n2)c1 +COc1ccc(CCNC(=O)CN(c2cccc(Cl)c2)S(=O)(=O)c2ccc(C)cc2)cc1OC +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1-c1cnn(C)c1 +Nc1ccc(NC(=O)C=C2CC(C(=O)O)Nc3cc(Cl)cc(Cl)c32)cc1 +CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O +Cc1cc(C)cc(COC(=O)C(Cc2c[nH]c3ccccc23)[N+](C)(C)C)c1 +Cc1cc(Oc2ccc3c(c2)OCO3)nc(Oc2ccc(-n3ccnc3)cc2C(F)(F)F)n1 +Cc1cc(CC(CCCCNC(Cc2ccccc2)c2ccc(F)cc2)C(=O)NO)cc(C)c1F +Cc1cc(-c2cccc(Cl)c2)ncc1C1CCCN1C(=O)c1ccncc1 +CCS(=O)(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21 +CN(C)c1ccc(-c2cnc3[nH]cc(-c4cn[nH]c4)c3c2)cc1 +O=c1[nH]c2c(O)ccc(C(O)CNCCOc3cccc(CNCCc4ccccc4F)c3)c2s1 +C=CC(C)(C)C12CC3C(=O)N4C(CC5(C(C)(C)C=C)c6ccccc6NC45)C(=O)N3C1Nc1ccccc12 +Cc1cnc(N2CCC(Oc3cc(F)ccc3Cl)CC2)nn1 +C[n+]1cc2c3c(ccc2c2ccc4cc5c(cc4c21)OCO5)OCO3 +CN(C)C(=O)C(C)(C)N=CC(C=N)c1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 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+CCCCCC1Oc2cccc(OC)c2-c2ccc(NS(C)(=O)=O)cc21 +CC(C)CCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cn1 +Brc1ccc2c(NC3=NCC4(CN5CCC4CC5)O3)nccn12 +O=C(Nc1ccc2nc(N3CCNCC3)[nH]c(=O)c2c1)c1ccc(C2CCNCC2)cc1 +COc1ccc(C=C2CC(CO)(COC(=O)c3c(C(C)C)cc(C(C)C)cc3C(C)C)OC2=O)cc1 +Cc1ccc(C#Cc2cccc(C#Cc3ccc(C)cc3)[n+]2C)cc1 +CSc1ncc(C(=O)N2CCNc3ccccc32)c(Oc2cc(Cl)ccc2Cl)n1 +CCCCNC(=O)C(C)CC(O)C1CSCCCCCCSCC(NC(C)=O)C(=O)NC(C)C(=O)N1 +CN1CCN(c2cc(N3CCOCC3)cn3c(=O)c(O)c(-c4ncc(Cc5ccc(F)cc5)s4)nc23)C1=O +CC1CCC2C(C)C(OC(=O)CCC(=O)O)OC3C4(C)CCCC1C23OO4 +Cc1cc(Cl)c(OCCOc2ccc(C3CCNCC3C(=O)N(Cc3cc(CNC4CC4)ccc3Cl)C3CC3)cc2)c(Cl)c1 +CCOC(=O)C1CC1Cc1c(Br)cc(OC)c(OC)c1Br +CCn1ccc(CNc2cc(OCC3CC3c3ccc(OC)cn3)nn(C)c2=O)n1 +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)C3CCN(C)C3)ncc2c1 +CC(C)CN1C(=O)N(C)C2(NC(=O)NC2=O)c2ccccc21 +CC(=O)c1cc(Cc2ccccc2)c(O)c2ccccc12 +O=C(CCCCC(=O)Nc1cc2c(Nc3ccc(Cl)c(C(F)(F)F)c3)ncnc2s1)NO +COc1ncccc1-c1nc(N2CCOCC2C)c2ccc(-c3cccc(CO)c3)nc2n1 +CC1CN(c2cc(Nc3cc(C4CC4)[nH]n3)nc(NCc3cc(-c4ccccc4)no3)n2)CCN1 +O=C(O)c1ccc(C2(NC(=O)C3CC4CC4CN3Cc3ccc(C(F)(F)F)cc3)CC2)cc1 +CC(C)Nc1cc(-n2nc(C(C)C)c3c(-n4cnc(-c5cccnc5)c4)ccnc32)ccc1C(N)=O +COc1ccc(-c2cnoc2-c2cc(OC)c(OC)c(OC)c2)cc1 +CC(CO)(CO)n1cc(C(=O)c2cncc(NC(=O)c3cccc(OC(F)(F)F)c3)c2)c2cncnc21 +COCC(c1ccc(Cl)c(Cl)c1)n1c(C(=O)OC)cnc1S +CN1CCC(Nc2cnc3ccc(C#CCNC(=O)c4cccn(C(CO)c5ccc(F)c(F)c5)c4=O)cc3n2)CC1 +O=C(Cc1ccc(Cl)c(Cl)c1)Nc1ccc(S(=O)(=O)O)cc1 +Cc1c(C)c2ccc(OCC(=O)NN3C(=O)CSC3c3ccc(Cl)cc3)cc2oc1=O +O=C(O)C1CCC(OCC2CC(F)CN2C(=O)Cc2ccc(Nc3nc4cc(F)ccc4s3)c(Cl)c2)CC1 +O=C(CCCN1CCN(c2noc3ccccc23)CC1)c1ccc(F)cc1 +CCOC(=O)C1CC12C(=O)Nc1ccc(-c3cccn3C)cc12 +O=C(Nc1cccc(O)c1)c1cccc(S(=O)(=O)Nc2cccc(O)c2)c1 +O=C(CCc1cccc(Cl)c1Cl)NC(Cc1ccccc1)C(=O)CCl +N#Cc1ccc(CC(=O)Nc2cc(C(=O)c3cn(C4COC4)c4ccncc34)ccn2)cc1C(F)(F)F +CCCc1cc(Oc2ccc(Cl)c(C)c2)ccc1OCCCOc1cccc(C2SC(=O)NC2=O)c1 +CC1=C2CC3C(CCC4c5c[nH]nc5CCC43C)C2CCC2(C1)OC1CC(C)CNC1C2C +COc1cc(C(c2c(O)oc3ccccc3c2=O)c2c(O)oc3ccccc3c2=O)ccc1O +CCCCCCc1cc(Cc2ccc(Br)cc2)c(C=C2N=C(c3ccc[nH]3)C=C2OC)[nH]1 +O=S(=O)(Nc1ncns1)c1cc(F)c(Oc2cc(Cl)c(F)cc2-c2ccn[nH]2)cc1F +Cc1c(-c2ccc(Oc3ncccc3C(F)(F)F)c3[nH]ccc23)n(C)c(=O)[nH]c1=O +Cc1ccc(C(=O)Nc2ccc(F)c(C3(C)CS(=O)(=O)N(C)C(=N)N3)c2)nc1 +CC1(C)C2CC=C(CN3CCC(NC(=O)Nc4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)C1C2 +CC1(C)c2cc(OCC(O)CO)c(Br)cc2C(=O)c2c1[nH]c1cc(OC(F)(F)F)ccc21 +O=C(c1cc2cc(OC3CCN(C4CC4)CC3)ccc2[nH]1)N1CCOCC1 +CC1(C)CC(O)(c2cncc(-c3cnc4c(c3)CCN4C(N)=O)c2)CCO1 +O=C(NC1CCCOC1)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +Cc1ccn2nc(C(C)Nc3ncnc(N)c3-c3cncc(OCC(F)(F)F)c3)n(-c3ccccc3)c(=O)c12 +O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1sccc12 +O=C(NC1CNCC1c1ccccc1)N1CCc2[nH]nc(-c3ccncc3)c2C1 +Cn1nc(-c2ccc(F)cc2)c(-c2ccc3nc(NC(=O)c4ccnc(F)c4)cn3n2)c1N1CCN(CC(N)=O)CC1 +COC(=O)c1ccc(C(=O)Nc2ccc(CCN3CCc4cc(OC)c(OC)cc4C3)cc2)cc1NC(=O)c1cnccn1 +OCC1OC(c2ccc(Cl)c(Cc3ccc(OCCOC4CCC4)cc3)c2)C(O)C(O)C1O +Cc1cc(C)cc(-c2cnc(-c3cccnc3)c(C(=O)NCc3ccc4c(c3)CCN4C)c2)c1 +NS(=O)(=O)c1cn(CC(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)ccc1=O +CNc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1 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+C=CC(C)(C)c1c2c(c(O)c3c(=O)c4ccc(O)c(O)c4oc13)C=CC(C)(C)O2 +Clc1ccc(-c2ccc(C#Cc3ccc(NCCN4CCCC4)cc3)nc2)cc1 +NC(=O)c1cc(-c2ccc(Cl)c(Cl)c2)cc2c1[nH]c1ccc(C(=O)NC3CCNC3)cc12 +CCOC(=O)c1c2c(n(C)c1COC)C(=O)C(=O)c1ccc(Br)cc1-2 +COC(=O)C1C(C=Nc2ccccc2O)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +CCC(CN(C)C)NC(=O)c1cccc2nc3ccc4c(OC)cccc4c3nc12 +CN1C(=N)N(C)C(=Cc2c[nH]c3cc(Cl)ccc23)C1=O +CCOC(=O)C(C#N)=CNc1ccc2c(c1)c1ccccc1n2CC +O=C(NCCCN1CCC(Cc2ccccc2)CC1)c1ccc(-c2ccccc2)cc1 +CN1CCN(CCNc2ccc(-c3cc4ncn(C)c(=O)c4c(NC4CC4)n3)cc2S(C)(=O)=O)CC1 +O=C1CCc2cc(C(c3ccncc3)c3cccc(F)c3)cc3c2N1CC3 +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccc(OC(F)(F)F)cc4)O2)C3=O)cn1 +COc1ccc(S(=O)(=O)n2ccc3cccc(-c4ccc(F)cc4)c32)cc1 +C1=C(Cc2ccccc2)CCN(CCC(c2csc3ccccc23)N2CCCCC2)C1 +O=C(O)C(=O)CC(=O)c1cc2ccccc2c2ccccc12 +CCOC(=O)c1cn2c(c1O)C(=O)N(Cc1ccccc1)CC2 +COc1ccc(CN2CCN(Cc3ccc(C)cc3)CC2)c(OC)c1 +COC(=O)C1C(O)C2(O)c3c(OC)cc(OC)cc3OC2(c2ccc(Br)cc2)C1c1ccccc1 +Cc1cc(C)c(CNC(=O)c2cc(-c3cnn(CCN4CCOCC4)c3)cc(N(C)C3CCNCC3)c2C)c(=O)[nH]1 +COc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCCC(NCc4ccccc4)C3)cc2)cc1 +O=C1c2cc(-c3cn[nH]c3)ccc2-c2[nH]c3cc(-c4cn[nH]c4)ccc3c21 +CC1CN(c2ncc(C(=N)N)cc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +CCCCc1cc2c(=O)c(-c3ccc(C)cc3C)c(C)[nH]c2cc1OCCOc1ccccc1 +O=C(C=Cc1ccc2c(c1)CN(S(=O)(=O)Cc1ccccc1)C2)NO +Cn1cnc2cnc(NC3=NCC4(CN5CCC4CC5)O3)cc21 +CCC1NC(=O)C(CCCNC(=N)NC)NC(=O)C(C)(NC(=O)C(C)C)CCNC(=O)C(c2ccccc2)NC1=O +O=C1NC(=S)SC1=Cc1ccc(-c2cccc(C(=O)O)c2)o1 +Cc1[nH]c2nc(-c3ccccc3)nc(NCc3ccncc3)c2c1C +Oc1ccc(C=Cc2ccc(C=Cc3ccc(O)cc3)c(OCCCC(F)(F)F)c2)cc1 +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1 +CC1Cn2c(=S)[nH]c3cccc(c32)CN1CC1CC1 +CCOC(=O)c1sc(NC(=O)c2cc3c(s2)CCC(C)C3)nc1C +CCOC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCc1cccc(Cl)c1 +O=C(NC1CN2CCC1CC2)c1cccc2oc(C3CC3)nc12 +Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N4CCNCC4)nc3)cc3c2C(C)CN3C2CCOCC2)c(=O)[nH]1 +CC1CN2c3c(cc4c(N5CC(CF)OC5=O)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CN1C(=O)CN=C(c2ccccc2F)c2c(Cl)cccc21 +CC(C)CC(CCCCn1cnc2c1NC=NCC2O)(CC(C)C)C(=O)O +CC(C)(C)n1nnnc1C(c1cccc(Nc2ccnc3cc(Cl)ccc23)c1)N1CCOCC1 +COc1ccc(-n2c3cnccc3c3cnc(Nc4ccc(N5CCNCC5)cn4)nc32)cc1 +COC(=O)CCC(=O)N(O)c1cccc(OCc2nc3ccccc3s2)c1 +CSC(=O)N1CC2(CCCCC2)CSC1=Nc1cccc2ccccc12 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)N1CCN(C)CC1 +CN(C)CC1CCC(Nc2c(C(=O)C3CCCC3)cnc3ccc(-c4cc(Cl)c(O)c(Cl)c4)cc23)CC1 +CC1CCCN1C1CCC(c2ccc(NC(=O)c3ccc(Cl)cc3)cc2)C1 +Cc1cc(C)cc(Cn2c(=O)cc(N)n(Cc3ccccc3)c2=O)c1 +Cc1ccc(-c2nnnn2CCCOc2ccc(S(=O)(=O)C3(C(=O)NO)CCOCC3)cc2)nc1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(C)(C)Oc4c(F)cccc43)cc21 +O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1c(Cl)cc(C(F)(F)F)cc1Cl +CC1(C)C(=O)N=C2c3ccccc3C(=O)C(=O)C21 +NC(CC(=O)N1CCCNC(=O)C1Cc1cnccn1)Cc1cc(F)c(F)cc1F +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCCN4CC5CCC4C5)cc3)oc2c1 +NC(=O)c1ccc(N2CCN(CCCCc3c[nH]c4ccc(C(N)=O)cc34)CC2)cc1 +C=CC[N+]1(C)CCC23c4c5ccc(O)c4OC2C(=O)CCC3(O)C1C5 +Clc1cccc2sc(NC3=NCC4(CN5CCC4CC5)N3)nc12 +COC(=O)C1C2CCC3CCC1N(CC2=Cc1ccc(-c2ccc(I)cc2)cc1)C3 +C=C(c1nc2ccccc2s1)C1CCN(CCc2ccc(OC)cc2)CC1 +O=C(NC1CCCC1)C(c1ccc(F)cc1)N(Cc1ccc(F)cc1)C(=O)CCl +CCOC(=O)C=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +CN1CCN(c2cccc(Nc3nc4c(Nc5ccccc5CN(C)S(C)(=O)=O)cccn4n3)c2)CC1 +COC(=O)CSc1nnc(Cc2c(NC(=O)c3ccccc3)sc3c2CCCC3)n1NC(C)=O +CN1CCC(COC(=O)c2cc(Cl)c(N)c3c2OCCO3)CC1 +CC(=O)N1CCc2cc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)ccc21 +CN(c1ccnc(Nc2cccc(S(C)(=O)=O)c2)n1)c1c(Cl)ccc2c1OCO2 +C=CCn1c(-c2cc3c(cc2C=C)OCO3)cc2ccc(OC)c(OC)c2c1=O +CC(C)C(C(=O)Nc1ccc(C(=O)NO)cc1)c1ccccc1 +CC(C)CCCSc1c(C#N)c(C(F)(F)F)nn1-c1ccc(S(C)(=O)=O)cn1 +CC(Oc1ccccc1)C(=O)N(Cc1cccc(Cl)c1)CC1CCCN1 +O=C1c2ccccc2NC(c2ccccc2Cl)N1N=C1CCCCCC1 +N=C(N)c1cccc(N2CC(O)CN(CC3CCN(Cc4ccccc4)CC3)C2=O)c1 +O=C(Nc1ccc2c(c1)OC(F)(F)O2)c1ccccc1NCc1ccnc(NCCO)c1 +c1ccc2sc(-c3ccc(OCCCCNc4c5c(nc6ccccc46)CCCC5)cc3)nc2c1 +CC1(O)CC(c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)C1 +C=CC12c3c4ccc(O)c3OC1C(=O)CCC2(O)C(N(C)CC1CC1)C4 +Cc1cc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5ccnn5C)nc34)CC2)no1 +Cn1cc2c(nc(NCc3ccc(Cl)cc3)n3nc(-c4ccco4)nc23)n1 +N#CC(=C(c1ccccc1)c1ccc(OCCN2CCOCC2)cc1)c1ccccc1 +O=C(NO)c1ccc2c(c1)CC(NS(=O)(=O)c1ccc(F)cc1F)CC2 +CCC(NC(C)(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2cccnc2)c1F +C#CCCCC(=O)c1cc(C(C)(C)C)c2c(c1)C(C)(C)CO2 +CC(C)CNC(=O)COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 +CN1C(CC(=O)c2ccccc2)CCCC1CC(OC(=O)c1ccccc1)c1ccccc1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ccnc(-n5cnnn5)c4)CC3CO2)c1C +CC(=NO)c1ccc(Nc2cc(C=Cc3ccc([N+](=O)[O-])o3)nc3ccccc23)cc1 +COc1ccccc1C(=O)NCCNC(=O)c1ccc(-c2cccc3[nH]nc(N)c23)cc1 +C=Cc1cn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-c3cnc4ccccc4c3)c12 +Cc1nc(Cl)c(-c2cc(C(=O)N3CC(c4ccc(C#N)cc4)C3)ccc2C)[nH]1 +CC(C)(NS(C)(=O)=O)C(NC(=O)c1ccc(-c2cc3cc(F)ccc3o2)cc1)C(=O)NO +Cc1ccc(C(=O)NCCO)cc1-n1cnc(SCc2ccc(F)cc2F)c(Cl)c1=O +CN(C)S(=O)(=O)Nc1ccc2c(c1)C(c1ccccc1Cl)=Nc1c[nH]nc1N2 +CC1CN2CCCC2C(=O)NC(C(=O)O)CSSCC(NC(=O)C23CC4CC(CC(C4)C2)C3)C(=O)N1 +COC(=O)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(=O)OC)C(C)C +COc1ccc(-c2ccc(-c3ccncc3)o2)cc1OC1CCCC1 +COc1cc2ncc3c(N)nc(-c4cncc(OCC(N)Cc5ccccc5)c4)cc3c2cc1OC +Cn1c(C(=O)c2ccc(Cl)cc2)cnc1CCCCN1CCCCC1 +C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(O)ccc3n2Cc2cccc(C(=N)N)c2)cc1 +Cc1c(C)c2c(c(C)c1N)CC(C)(CNCc1ccccc1)O2 +O=C(O)C1=C(C(=O)Nc2ccc(-c3ccccc3)cc2)CCC1 +CC(=O)Nc1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1 +CC(C)Oc1ccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cc1 +CN(CCCNc1ccnc2cc(Cl)ccc12)C(=O)COc1ccccc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(Nc2cccc(Cl)c2)CC1 +O=C(NCCNS(=O)(=O)c1cccnc1)c1cccc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +Clc1ccc2c(N(CCCN3CCCCC3)C(=NCCCN3CCCCC3)c3ccccc3)ccnc2c1 +CCCN(CCC1CCC(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)CC1)C1CCc2nc(N)sc2C1 +O=C(NC1CCN(Cc2ccc(OCCCN(C3CC3)C3CC3)c(F)c2)CC1)c1cc(=O)c2ccc(F)cc2o1 +Nc1cc(C(=O)N2CCCCC2)cc2nc(-c3ccco3)nn12 +COc1ccccc1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 +O=C(Nc1ccc(-c2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1)C1CN2CCC1CC2 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+O=c1[nH]c(O)c(Cc2ccc(OCC3CCCCC3)c(Cl)c2)s1 +CCC(C)(C)c1ccc(S(=O)(=O)Nc2ncnc(OCCOc3ncc(Br)cn3)c2-c2ccc(C)cc2)cc1 +CCCCC1(CC)CS(=O)(=O)c2cc(CP(=O)(O)O)c(OC)cc2C(c2ccccc2)N1 +CCC1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC3CCCC3)nc2N1C1CCCC1 +CC1CCC(Cn2c(N3CCCC3C(=O)N(C)C)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CC(C)(C)CCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2cccs2)c1 +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(N(CCN4CCCC4)C(=O)c4ccccc4)cc3)nnc2c1 +Cc1nc2cccnc2n2c(-c3cc(OCC4(C)COC4)ccc3Cl)nnc12 +COc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COCC(F)(F)F)c2)c1F +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1c(F)cccc1C(F)(F)F +CCCCNC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccccc3F)c2C1 +CONC(=O)c1cccc(Oc2cc(CN)cc(C(F)(F)F)n2)c1 +COc1cc(C(F)(F)F)ccc1-c1ncc(F)c2cc(S(=O)(=O)Nc3nccs3)ccc12 +CC(C)(C)C1CCC2(CC1)CN(c1ccccc1Cl)C(=O)N2Cc1ccc(C(=O)Nc2nn[nH]n2)cc1 +CN(c1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)c(Cl)c1F)C2)S(C)(=O)=O +CCc1cc(CCC(=O)c2sc(CC)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNC(=O)CO +CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NCCO +O=C1C=C(NCCCCCCCCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)c2ccccc21 +CCNc1nc2cc(F)c(OC)cc2cc1Cc1c(=O)[nH]c(CC)c2cc(OC)c(OC)cc12 +COc1ccc(-c2cc(-c3ccc4nccn4c3)cnc2N)cn1 +Cc1ncc(C)n2nc(CCc3nc(-c4cscn4)cn3C)nc12 +CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(N)=O)cc3)cc2s1 +O=S(=O)(c1ccccc1)N(CCN1CCOCC1)c1sc2ccccc2c1Br +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCCc1ccncc1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)N(C)C)n1)CCN2 +COCc1cn(C2=NCC(=O)N3CCc4c(cccc4C4CC4)C3=C2)cn1 +Cc1cc(C#N)cc2nc(-c3ccc(NC(=O)COC4CCN(C(=O)OC(C)C)CC4)cc3)oc12 +N#CC(c1cccnc1)N1CCN(C(=O)C(c2ccccc2)c2ccccc2)CC1 +COc1cccc(NC(=O)N2CCC(c3nc(-c4ccc5ccccc5n4)no3)CC2)c1 +COc1ccc(-c2csc(C=Cc3cccc(C(CCc4ccccc4C(C)(C)O)SCC4(CC(=O)O)CC4)c3)n2)cc1 +OCC1OC(n2c(Nc3ccccc3)nc3c(Nc4ccccc4)ncnc32)C(O)C1O +O=C(NCc1nc(Cc2ccccc2)cs1)C(O)C(O)C(=O)N1CCCC1c1ccccc1 +COc1cc(-c2ccc3ncc(S(C)(=O)=O)c(Nc4ccc(CN(C)C)cc4)c3n2)cc(Cl)c1O +CC(C)Oc1cnc2c(Nc3cc(Cl)c(F)c(C4(CF)N=C(N)OC5CC54)c3)nccc2n1 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+O=c1c2cnc3ccccc3c2ncn1CCCN1CCN(c2cccc(Cl)c2)CC1 +N#CC(Cc1ccc(C2CCCCC2)cc1)NC(=O)C1NC2CCC1C2 +COc1ccc(S(=O)(=O)C(C)(CC=Cc2ccccc2)C(=O)NO)cc1 +O=C(c1cccnc1)N1CCN(c2cnc3ccn(S(=O)(=O)c4cccc5nonc45)c3c2)CC1 +COc1ccc(C)cc1NC(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CSc1ccc(CC2CCN(C3(C)CCN(C(=O)c4c(C)cccc4C)CC3)CC2)cc1 +COc1cc2c(NC3CCN(C(C)C)CC3)nc(N3CCCN(C(C)C)CC3)nc2cc1OCCCN1CCCCC1 +CNCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +O=C1CC(C(=O)Nc2cc(-c3cccc(OC(F)(F)F)c3)n(CCc3ccccc3)n2)CN1 +N#Cc1ccc2nc(Nc3ccc(Oc4ncccc4C(F)(F)F)cc3)[nH]c2c1 +Cc1ncsc1CNc1nc(-n2ncc3ccncc32)nc(N)c1Br +Cc1ccc(C(=O)Nc2ccc3c(c2)C2(CCOC(N)=N2)c2cc(C4=CCCOC4)ncc2O3)nc1 +COc1ccc(Cn2cnc3c2CC(C(=O)O)N(C(=O)C(c2ccccc2)c2ccccc2)C3)cc1F +CNC(=O)c1cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(OC)c2[nH]1 +CCCCCCCCCCCCCCCCC(CC(=O)O)C(=O)NC(C(=O)NC)C(C)(C)C +CC(=O)NCC1CN(c2ccc(-c3ccc(CNCc4ccncc4)cc3)c(F)c2)C(=O)O1 +CC(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccncc3)nn2)CC1 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+CN1CCCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)CC1 +NS(=O)(=O)c1cccc(NC(=[Se])NC(=O)c2ccccc2)c1 +CC(=O)NCCc1c[nH]c2ccc(OC(=O)NCCCCCCCCNc3c4c(nc5ccccc35)CCCC4)cc12 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCN(S(C)(=O)=O)CC4)cc3OC)ncc2C(F)(F)F)c1 +O=C(Nc1cccc(OCCCN2CCOCC2)c1)Nc1ccc2c(c1)OCO2 +COC(C1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1)C1CCCN1C +O=C1OC(CO)(COC(=O)c2ccc([N+](=O)[O-])cc2)CC1=CC1CCCCC1 +O=C(O)CC1CCC(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)CC1 +O=C(Nc1ccc2c(c1)OCO2)c1scnc1CCc1ccncc1 +CCC(=O)Nc1cc(-c2ccccc2)nc(-c2ccccc2)n1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC(NCc1ccccn1)c1ccccc1 +COc1cc2ncnc(N3CCC(Oc4ccccc4C)C3)c2cc1OC +CNC(Cc1ccccc1)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)c1nc2ccc(C(N)=O)cc2s1 +COc1ccccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1 +COCCN(C)C(=O)c1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 +CN1C(=O)C(=C(C#N)C#N)c2cc(S(=O)(=O)N3CCCC3COc3ccccc3)ccc21 +O=S(=O)(NC1(c2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1)c1ccc(F)cc1 +N=C(N)c1cc2cc(-c3cccc(-c4ccccc4)c3O)[nH]c2cc1F 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+COC1=CC(=O)c2c(COc3ccccc3[N+](=O)[O-])c(C)n(C)c2C1=O +Cc1c(OCCN2CCOCC2)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12 +CNCCC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 +COc1ccccc1CNc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CC(C)(C)OC3 +O=C(OC1CNC(C#Cc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2)C1)N1CCNCC1 +Cc1ccccc1C=CC(=O)NC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(C)C2C5 +CCCCCCCCCCCCCCCCCCNC(=O)N1CCN(C(=O)Nc2ccc(Cc3noc(=O)[nH]3)cc2)CC1 +CCn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC(N)C(F)CC1 +CS(=O)(=O)c1cc(Br)c2c(c1)c1c(n2Cc2ccc3ccc(Cl)cc3n2)C(CC(=O)O)CC1 +CCOc1nc(NC(=O)Cc2ccc(C)cc2)cc(N)c1C#N +CC1(C(=O)O)CCCCC1Nc1nc(-c2c[nH]c3ncc(Cl)cc23)ncc1F +O=C(Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c2c1OC1(CCS(=O)(=O)CC1)O2 +Cc1cccc(-c2cc(-c3ccco3)nc(N)c2C#N)c1 +CN(C)CCn1c2c(c3ccccc3c1=O)C(=O)c1cc(O)ccc1-2 +COC1CCC2(C)C3CCC4C(=CCC5C(C)(C)C(OC(=O)CN)CCC45C)CC3(C)CCC2C1(C)C +N#Cc1ccc2c(c1)CN(CCC1CC1CNC(=O)c1cc3ccccc3[nH]1)CC2 +O=C(c1ccc(OCCCN2CC3CC2CN3C(=O)c2ccco2)cc1)C1CC1 +Cc1ccc(SCC(=O)Nc2cc([N+](=O)[O-])ccc2O)cc1 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+O=C(N1CC(O)CCC1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 +COC(C)C(=O)N(c1ccccc1F)C1CCN(CCc2cccs2)CC1C +CCN(CC)CCCn1c(=C2C(=O)Nc3ccc(F)cc32)sc(=Cc2ccc3c(c2)OCO3)c1=O +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c(OCC3CNC3)cc2Cl)cc1 +COc1cc(CC(C(C)=O)C(=O)NCCCCCCNc2c3c(nc4ccccc24)CCCC3)ccc1O +CCCc1ccc(-n2[nH]c3c(cnc4cc(C)ccc43)c2=O)s1 +O=C1OCC(c2ccccc2)N1c1ccn2ncc(-c3ccc(-c4ncc[nH]4)cc3)c2n1 +CSc1c(Cl)nc(-c2ccc(NC(=O)Nc3cccnc3)cc2)nc1N1CCOCC1 +CSC(=S)N1CC2(CCCCC2)COC1=Nc1ccc(C#N)c2c1CCCC2 +Cc1c(Oc2cnc(C(=O)N3CC(C)(O)C3)cn2)ccc2c1B(O)OC2 +N#Cc1ccc(NC(=O)Nc2cccc(-c3cccc(N4CCCC4)n3)c2)cc1 +CC(C)(C)NC(=O)N1CCn2c(c(C(N)=O)c(-c3cccc(F)c3)c2C2CC2)C1 +CC1(C)CC(c2ccccc2)=NN(C(=O)c2ccc(Cl)c(Cl)c2)C1 +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)CN4CCN(C(=N)N)CC4)cccc2-3)cc1 +CCOC(=O)c1c[nH]c2ncnc(-c3cccc(O)c3)c12 +COc1ccc(-n2nnc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)c(Cl)c1 +COc1ccccc1-c1cccc(S(=O)(=O)c2cc(C(=N)N)sc2SC)c1 +CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4c(c3)CCO4)n2)c(=O)c1=O +O=C(Cc1cccc2ccccc12)N1CCC(CNCCCCN2CCCCC2)CC1 +CNC(=O)C(NC(=O)C(CCCCCCCCCCCCCCO)CC(=O)NO)C(C)(C)C +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CC2OC(=O)C(=C)C23CCCC3)CC(O)CC1O +O=C(O)c1ccc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1Cl +CNC(=O)CN1CN(c2ccccc2)C2(CCN(C(=O)OCc3cc4c(cc3Cl)OCO4)CC2)C1=O +O=C(Nc1ccccc1)NC1C(=O)N(CC23CC4CC(CC(C4)C2)C3)c2ccccc2N(C2CCCCC2)C1=O +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2ccnc(F)c2)c1 +CC(=O)NC1C(C(O)C(O)CO)OC(C(=O)O)=CC1N(CCCC(=O)N1CCNCC1)C(=N)N +CC1(C)C(=O)Nc2nc(-n3nc(Cc4ccccc4F)c4cc(F)ccc43)nc(I)c21 +O=C(Nc1ccc(C2CNCCO2)cc1F)c1ccn(-c2ccc(F)cc2)n1 +CCN1CCN(Cc2ccc(-c3ccc4c(Nc5cc(OC)c(Cl)cc5Cl)c(C#N)cnc4c3)cc2)CC1 +COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)c4c(OCc5cccc(Br)c5)cccc4o3)c2c1 +O=C(c1cccc(N(Cc2ccccc2)c2ccc([N+](=O)[O-])cc2)c1)N1CCCC1 +Cc1ccc(N(C(=O)OCC2CCC(COCC(=O)O)CC2)c2cccc(F)c2)s1 +CCOc1cc(C)c(Nc2ccnc(N3CCN(c4ccc(OC)cc4)C(C)(C)C3)n2)cc1C(C)C +Cc1cc(C(=O)c2ccccc2C)ccc1Nc1ccccc1N +Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3ncsc3c2)n1 +CSc1cc(F)cc(C(CO)NC(=O)c2ccc(-c3nc(C4CCOCC4)cnc3N)cc2F)c1 +CCOc1cccc(F)c1CCNC(=S)Nc1ccc(C)cn1 +COCC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C4CC4)nn3)c2)c2cnc(N)nc21 +FC1(F)Oc2ccc(Nc3nnc(-c4cccnc4NCc4ccccn4)o3)cc2O1 +CCC(C1=C(CCN(C)C)Cc2ccccc21)c1ccccn1 +CCCNC(=O)OCC1OC(n2cnc3c(NC4CCCC4)nc(Cl)nc32)C(C)(O)C1O +Cc1ccc2c(-c3nnc(SCCN4CCc5cc6nc(C)oc6c(C)c5CC4)n3C)cccc2n1 +O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cc2ccncc2)c1 +CN(C(=O)C(C#N)=Cc1cn(CC(=O)O)c2cc(Cl)ccc12)c1ccccc1 +COc1ccc(OC)c(-c2cc(NC(C)=O)nc(-c3cc(OC)ccc3OC)c2)c1 +CNC(=O)c1cnc(N)c2cc(-c3ccccc3)sc12 +O=c1cc(-c2ccccc2)n(-c2cccc(-c3ccccc3)c2)cc1O +Cn1cc(C(=O)CCCCCCCc2ccccc2)cc1C=CC(=O)NO +CC(=O)c1ccc(Cl)cc1OCC(=O)Nc1ccccc1C(=O)O +Cc1ccccc1-c1ccccc1CN(C(=O)c1ccc(-c2ccc(C#N)cc2)o1)c1ccc(N2CCNCC2)cc1 +O=C(c1ccnc(Cl)c1)N1CC2(CCN(CC=Cc3ccc(Cl)cc3)CC2)c2cc(F)ccc21 +COc1ccc2c(c1)CC(CCN(C)C)=C2C(C)c1cnccn1 +Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)c(C(=O)Nc2ccc(Br)cc2)c1 +CCN1CCCC(CN2CCN(C(=O)Nc3ccc(Cl)c(Cl)c3)CC2)C1 +COC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(C(=O)NCCCCCCC(=O)NO)cc1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(N2CCOCC2)nc1 +CCC(=O)N1CCC(N2C(=O)N(c3ccccc3C)Cc3cnc(Nc4ccc(N5CCN(C)CC5)c(C)c4)nc32)C1 +CCC(NC(=O)c1c([S+]([O-])CC(=O)N(C)C)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(N(CC)CC)n3)C2)cc1 +CCC1CCCCN1CCCOc1cc2ncc(C#N)c(Nc3ccc(Sc4nc(C)c(C)n4CC)c(Cl)c3)c2cc1OC +N#CC1CCCN1C(=O)CNC(=O)c1ccnc2cnccc12 +O=C(Nc1ccc(C(F)(F)F)cc1)c1csc(Nc2c(Cl)cncc2Cl)n1 +CC(C)n1ncc2c(C(=O)Nc3cc(S(N)(=O)=O)ccc3F)cc(-c3cccs3)nc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCC(C(=O)NCC(F)(F)F)CC1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5cccc(F)c5)C4)c3)nc2n(CCC)c1=O +O=C(O)C(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C1OCOC1C(=O)Nc1c(Cl)cccc1Cl +CCC(=O)C1C2CCC(CC1c1ccc(I)c(F)c1)N2 +CC1CN(c2ccc(-n3cnc4c(-c5ccc(F)cc5)cccc4c3=O)cn2)CC(C)O1 +N#CC1CCN(CCC2CCOCC2)CC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +NC(Cc1cc2ccccc2cc1CP(=O)(O)O)C(=O)O +O=C1OC(CN2CCC(O)(c3ccc4c(c3)OCO4)CC2)CN1c1ccc(F)cc1 +Cc1cc(C)cc(C(F)=C2CCC(NC(=O)c3ccnc4ccccc34)CC2Cc2ccccc2)c1 +CCNC(=O)Nc1nc2cc(-c3cncnc3)ccc2[nH]1 +O=C(OCCCCN1CCC(c2ccccc2)CC1)C1(c2ccccc2)CCCC1 +COc1ccc(OC)c(C=Cc2cc(OC)c(O)c(OC)c2)c1 +CCC(CC(=O)O)c1cccc(OCc2ccc(-c3cc(OC)ccc3F)c(C(C)(C)C)c2)c1 +CN(C)CCn1cc(NC(=O)c2cccc(-n3cc(NC(=O)Nc4ccccc4Cl)cn3)c2)cn1 +Cc1cc(COc2c(C)cccc2-c2csc(N3CCC4(C(=O)O)CC4C3)n2)cc2c1CN(CC1COCCO1)CC2 +CC1OCCC1OC(=O)NC(CSc1ccccc1)C(O)CN1CC2CCSC2CC1C(=O)NC(C)(C)C +CCC(O)(CC)C(C)Oc1ncc(C(F)(F)F)cc1-c1ccc(S(C)(=O)=O)cc1 +CC(CCNCC12CC3CC(CC(C3)C1)C2)Nc1c(F)cnc2ccccc12 +O=C(Nc1ccc2c(c1)S(=O)(=O)C=C2)c1cc(Cl)ccc1OCCN1CCOCC1 +CNc1ccc(C#CCC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N(C)C2CCCC2)cn1 +Cc1c(NC2CC2)nc(C2CC2C)nc1N1CCCCCC1 +COc1cnc2ccc(C(C)(F)c3nnc4c(F)cc(-c5cc(C)no5)cn34)cc2c1 +CC(C)(C#N)Cn1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +O=C(Nc1ccc(C2CCCNC2)cc1)c1ccc(Cl)nc1 +CCCCS(=O)(=O)N1CCN(Cc2c3c(nc4ccccc24)-c2cc4c(c(=O)n2C3)COC(=O)C4(O)CC)CC1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OCCN1CCOCC1 +O=C(CCCCCS)Nc1cc(CCC(=O)c2c(O)cc(O)cc2OC2OC(CO)C(O)C(O)C2O)ccc1O +CCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4CC3C4)n2)cc1C1CC1 +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccc(Cl)c(Cl)c4)O2)C3=O)cn1 +CCNC(=O)C1OC(n2cnc3c(NCC4CC5CC4C4OC54)ncnc32)C(O)C1O +O=C(O)c1cccc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)n1 +CC1CN(CCc2ccccc2)CCC1N(C(=O)c1ccco1)c1ccccc1Cl +CCn1nc2c(c1C)-c1nc(Nc3ccc(CN(C)C)cc3)ncc1CC2 +O=C(NC12CCCC(C#Cc3ccccn3)(CC1)C2)c1ccc(F)cn1 +COc1ccc(C(=O)Nc2ncncc2Cl)c2cc(C(C)=O)oc12 +COC(=O)c1ccc(-c2ccc(OC3OC(CO)C(O)C(O)C3O)cc2)cc1 +COc1ccc(-c2nsc3c2NC(=O)CC3c2ccc3c(c2)OCCO3)cc1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(OCc4ccccc4)c3)C2)cc1 +Cn1c(C(=O)NC2CCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1-c1cn[nH]c1 +Cc1cn(-c2ccc3n(c2=O)CCN(C2CCCC2Oc2ccccc2C(F)(F)F)C3=O)cn1 +Nc1cc2n[nH]c(=O)n2c2cc(-c3ccoc3)ccc12 +CN1CCN(CCNc2nc(Nc3ccc(F)c(Cl)c3)nc3cccnc23)CC1 +CCC1COc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc2N1CC +CCc1cc2c(cc1NC(=O)N1CCC(C(C)(C)O)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3cccc(C(=O)NCCCN4CCN(C)CC4)c3)nnc2c1 +Cc1ccc(C(=O)NCc2ccc(C(C)(C)C)cc2)cc1Nc1ncnc2cnc(N3CCCCC3)nc12 +O=C(NCCCc1ccccc1)C12CC3CC(CC(C3)C1)C2 +COc1cc2nccc(Oc3ccc(NC(=O)c4cc(-c5cccs5)cn(-c5ccccc5)c4=O)nc3)c2cc1OC +CC(C)(Cc1ccc(F)cc1C#N)C1OCC(CC=CCCC(=O)O)C(c2cccnc2)O1 +O=C1N(Cc2cccc(-n3nccn3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +O=C(NCC(NS(=O)(=O)c1ccccc1)C(=O)O)c1cc2cc(CCC3CCNCC3)sc2s1 +NC(=O)c1cccc2[nH]n(C3CCN(Cc4ccco4)CC3)c(=O)c12 +CCOc1ccc(-n2c(C)c3c(C)nnc(NCc4ccc(OC)cc4)c3c2C)cc1 +C=CCn1c(O)c(N=NC(S)=Nc2ccccc2F)c2ccccc21 +Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN(C(C)C)C(C)C)cc2)c2ccc(O)cc12 +CCn1c(NC(=O)c2ccc3cc4n(c3c2)C(C)CCNC4=O)nc2ccccc21 +COc1cc(C(=O)NN=Cc2ccc(OC)c(CN3CCN(c4ccc(F)cc4)CC3)c2)ccc1O +O=c1[nH]c(N2CCOCC2)nc(NCCNCCO)c1-c1ccc2ccccc2n1 +OCc1cc(C(O)CNCCCCCCOCCCCc2ccccc2)ccc1O +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(C)CC2)cc1 +Nc1ccc(-c2ccc3cc(NC(=O)C4CC4)ncc3c2)cn1 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+O=C(NNc1ccc(N(CCCl)CCCl)cc1)Nc1cc(-c2ccccc2)nc2cc3c(cc12)OCO3 +NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2[N+](=O)[O-])cc1 +Cc1ccc(Nc2cnc(-c3ccccc3)c(F)c2)c(C(=O)O)c1 +Cc1ncc(F)cc1C1CCCN1c1ccn2ncc(C(=O)NC3CCC(O)C3)c2n1 +CC1(C(=O)O)CCc2ccc(OCCCOc3ccc(OCC4CC4)cc3Cl)cc2O1 +CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1cccc(Cl)c1 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=S)Nc1cccnc1)CC2 +Cc1cccc(N2CCCCC2)c1CNC(N)=NC(=O)c1ccc(CC(N)C(=O)O)cc1 +CCN(CC)C(=O)Cc1c(-c2ccc(OCc3ccccc3C(F)(F)F)cc2)nn2c(C)cc(C)nc12 +COc1cc(C#CCC[N+]23CCC(CC2)CC3)cc(OC)c1OC +COc1ccc(-n2c(Sc3nnc(N)s3)nc3ccc(Cl)cc3c2=O)cc1 +CCCCNC(=O)c1ccc2c(c1)N=C(c1ccccc1Cl)c1ccccc1S2 +Cc1sc(NC(Cc2ccccc2)(c2cc(F)cc(OC(F)(F)C(F)F)c2)c2ccc(Cl)cn2)nc1C(F)(F)F +Cc1nnc(Nc2cc(C(=O)NC3CC3)ccc2Cl)c2cnn(-c3ccc(F)cc3)c12 +CCCCCCCN(CCc1ccc(OC(C)(CC)C(=O)O)cc1)c1nc2ccccc2o1 +NS(=O)(=O)c1ccc(-n2nc(CCCNC(=O)Nc3ccc(C(F)(F)F)cc3)cc2-c2ccccc2)cc1 +Cc1ccc(-n2nccn2)c(C(=O)N2C3CCC2C(COc2nc4ccccc4nc2C(F)(F)F)C3)c1 +CCCCC(NC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O 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+N#Cc1cc(-c2ccc3c(c2)NC(=O)CO3)n(-c2ccc(F)cc2)n1 +Nc1nc(N2CCNCC2)c2oc3ccc(Cl)c(Cl)c3c2n1 +COCCN(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +CCCCCC[N+]1(C)C2CCC1CC(CC(C#N)(c1ccccc1)c1ccccc1)C2 +O=C(C(NS(=O)(=O)c1cnccc1NC(CO)Cc1ccccc1)c1ccc2ccccc2c1)N1CCC(CCF)CC1 +CCC(C(C)C(C)(C)O)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COC(=O)c1ccc(Nc2nc3ccc(C(=O)N(CCC(C)C)CCC(C)C)cc3n2CCCN2CCCCC2)cc1 +CN(C)CCNS(=O)(=O)c1ccc(-c2ccnc3[nH]ccc23)cc1 +O=C(Nc1cc(Cl)ccc1-c1ccc(F)cc1)NC1(C(=O)O)CC1 +O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)c1ccccc1 +CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCCc1c[nH]c2ccccc12 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2-c1ccc2cc[nH]c2c1 +CC(NC(=O)c1ccnnc1)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +Cc1ocnc1-c1ccc(OCCNCC(O)c2cccnc2)cc1 +CC(O)c1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 +CCCCc1nc(Cl)c(CC(=O)O)n1Cc1ccc(NC(=O)C(Cc2ccccc2)n2cccc2)cc1 +Cc1ccccc1NC(=O)NCc1ccc(-c2n[nH]c3c2Cc2cc(CN4CCN(C)CC4)ccc2-3)s1 +COc1cccc(C(Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)C(C)NS(=O)(=O)C2CC2)c1 +Cn1ncc(NC(=O)c2nc(-c3ccncc3F)sc2N)c1N1CCC(N)CC(F)(F)C1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C(C)C)CC2C +O=C(c1ccc(Oc2nccnc2N2CCCCC2)cc1)c1nc2ccccc2[nH]1 +c1cc(-c2ccc(CCN3CCCCC3)cc2)ccc1CCN1CCCCC1 +COc1cc2c(Nc3c(Cl)ccc4c3OCO4)ncnc2cc1OCC1CCN(C)CC1 +CC(c1ccccc1)N(C)c1ccnc(-n2cnc3ccncc32)n1 +CCC(C)C(CN(CC(=O)NC(CCSC)C(=O)O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccccc1 +O=C(NO)c1cnc(N2CC3C(C2)C3NCC2CCCCC2)nc1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC(CNS(=O)(=O)c1cccc(C(N)=O)c1)c1ccccc1 +NC1CN(c2ccc(-n3ccc(OCc4ccccc4)cc3=O)cn2)CC1c1cc(F)ccc1F +COc1ccccc1Oc1ccc(-c2cn(C3CCCC3)c3ncnc(N)c23)cc1 +O=C(Nc1ccc2[nH]ncc2c1)c1cc(N(CC2CC2)C2CCCCC2)ncn1 +COc1cnc(C(=O)Nc2ccc3c(c2)C2(CCOC(N)=N2)c2cc(-c4ccnc(F)c4)cc(F)c2O3)cn1 +O=C(NO)C1CN(c2ccc(C#CC#CC3CC3)c(F)c2)C(=O)O1 +CNC(=O)c1ccc(Nc2nccc(-c3cnc(COC)n3C(C)C)n2)cc1 +Cc1nc(N)ccc1CNC(=O)Cn1c(C)cnc(NC(C)(C)Cc2ccccc2)c1=O +CC1COC2=C1C(=O)C(=O)c1c2ccc2c1CCCC2(C)C 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+CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCC4(C(F)(F)F)CC4)c3Cl)C2)cc1 +C=CC(=O)Nc1cccc(-c2c[nH]c3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn23)c1 +NC(=O)c1nn(-c2cccc(F)c2)c2c1ccc1[nH]ncc12 +CN(C)CC1CC2c3cc(F)ccc3Cc3ccc(F)cc3N2O1 +N#Cc1ccc(Cn2cncc2CNc2scc(-c3ccc(Cl)cc3)c2C#N)cc1 +C=CCC1Oc2cccc(C(=O)OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +CC(C)CCS(=O)(=O)C1CC2CN(c3ccc(OC(F)(F)F)cc3)C(=O)N2C1 +O=C(CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)N1CCC2(CCCC2)CC1)NC(Cc1ccc(Cl)cc1)C(=O)O +COc1ccccc1N1CCN(CCCCNC(=O)C=Cc2ccc(Cl)cc2)CC1 +c1ccc(COc2ccc(-c3cnc4c(-c5nnn[nH]5)cnn4c3C3CCCCC3)cc2)cc1 +Nc1nc(OCCc2ccccc2Cl)nc2c1ncn2C1OC(CO)C(O)C1O +O=P(O)(O)OC1COC(Cc2ccccc2)C1OC1OC(CO)C(OP(=O)(O)O)C(OP(=O)(O)O)C1O +Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(N5CCCC5=O)cc4)c3Cl)c2n1 +CCN1CCC(c2ccccc2)=C(C(=O)OCCCc2ccc(OC)cc2)C1 +Cn1ccnc1-c1ccc2c(c1)N(c1nc3c(s1)C(=O)NC(C)(C)C3)CCO2 +O=C(c1ccc(F)cc1OCC(O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCC(O)C1 +COc1cc(Nc2c(C#N)cnc3cc(-c4csc(CN5CCOCC5)c4)ccc23)c(Cl)cc1Cl +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(F)c(Nc2ccc(N3CCN(C(C)=O)CC3)cc2OC)n1 +O=C(O)CC(=O)Nc1ccc(-c2cnc(N3CCOCC3)c3nc(C=Cc4ccc5ccccc5n4)cn23)cc1 +Cc1cc(C)c2c(n1)N=C(c1ccc(-n3c(C)nc4cnccc43)cc1)CC(=O)N2C +COc1ccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CCN(CC4CCOCC4)CC2C)C3(C)C)nc1 +O=c1cc(C=Cc2cccc(F)c2)c2cc(C(c3ccc(Cl)cc3)c3nccs3)ccc2[nH]1 +Cc1cc(C)cc(OCC(=O)NNC(=S)NC(=O)C2CC2)c1 +Cc1cc(COc2ccc(C(=O)NC3CC(O)CC3C(=O)NO)cc2)c2ccccc2n1 +CCCOc1ccc2c(-c3ccc4c(c3)OCO4)c(C(=O)O)n(Cc3ccc4c(c3)OCO4)c2c1 +COc1ccc(-c2cc(NCc3cncn3Cc3ccc(-c4ccccc4)cc3)ccc2-c2nc3ccccc3s2)cc1 +COc1cc(-n2cnc3sc(-c4ccccc4)cc3c2=O)ccc1OCCN1CCCC1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(CNc4cc[nH]n4)o3)nc2n1 +COc1cc(N)c(Cl)cc1C(=O)NCC1CCNC(Cc2c[nH]c3ccccc23)C1 +Cn1c(=NNC(=O)CC2CCCC2)sc2cc(OC(F)(F)F)ccc21 +CCN(CC)CCNC(=O)c1cccc(S(=O)(=O)Nc2nnc(S(N)(=O)=O)s2)c1 +CCOC(=O)C1=C(CN2CCOCC2C(=O)O)NC(c2nccs2)=NC1c1cccc(F)c1Cl +Cc1ccc(-c2cnc(NC(=O)c3ccccc3)s2)cc1 +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NCC(c1cc(Cl)cc(Cl)c1Cl)N1CCC(N2CCCCC2)CC1 +Fc1cccc(-c2[nH]c(-c3ccccc3)nc2-c2ccncc2)c1 +Cn1c2cc(S(=O)(=O)CCCN3CCCC3)c(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +COCCCc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +COCC(O)C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +Cc1cc(=O)oc2c1ccc1oc(=N)c(C(=O)NCc3ccccc3Br)cc12 +CC12CCC(O)CC1=CCC1C2CCC2(C)C(c3ccno3)CCC12 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(OCc4ccccc4)cc3)nn21 +CNC(C)C(=O)NC1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(C)=O)C1C +O=C(NCCn1cccc1)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +NC(=O)c1cccc2[nH]n(C3CCN(C4CCC4)CC3)c(=O)c12 +Oc1ccc(-c2c(-c3ccccc3)[nH]c3ccccc23)cc1 +CNC(=O)c1cncc(-c2c[nH]c3ccc(-c4nnc(NC(C)C)o4)cc23)c1 +O=C(NS(=O)(=O)c1ccc(Br)cc1)c1ccc(Cl)cc1Cl +COC(=O)C(Cc1cccc(C(=N)N)c1)C(NC(=O)c1ccc(-c2cccc(CN)c2)cc1)C(C)C +NC1CCN(Cc2ccn3ncnc(Nc4ccccc4)c23)CC1 +N#Cc1ccc(S(=O)(=O)N2CC(O)(COc3ccc(C#N)c(Cl)c3)C2)c(Cl)c1 +O=S(=O)(c1ccc(F)cc1)N(CCCN1CCN(c2ccccc2)CC1)CC1CC1 +CNC(=O)C1OC(n2cnc3c(NCc4cccc(I)c4)nc(NC)nc32)C(O)C1O +CC(C)c1ccccc1OCCN1CC(NS(=O)(=O)c2ccc(F)cc2)C1 +CC1CN(C(=O)C2(C#N)CCC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cnn(C)c3)nc12 +Cc1cc(Oc2cccnc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +COc1cc(CN(CC2CC2)C(CC(=O)O)c2ccc(Cl)c(Cl)c2)ccc1SCCN1C(=O)CCC1=O +COc1ccc(-c2cccc(C(F)(F)F)c2)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C)N(CC(=O)NCC1CCN(c2ccc(C(F)(F)F)cc2)C1)S(=O)(=O)c1ccc(F)cc1 +O=C(NC1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1 +CCN(c1nc(C)cc(-c2cccc3ccccc23)n1)c1ccc(C(C)C)cc1Br +CC(C)(C)OC(=O)NCCCCCNC(=O)c1cc(-c2ccncc2)n2ncnc(N)c12 +CN(CC(C)(CCN1CCC2C(CCC(=O)N2Cc2ccccc2)C1)c1ccccc1)S(=O)(=O)c1ccccc1 +O=C(Nc1ccc(I)cc1)C1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 +Cc1cc(C(=O)N2c3cccc(O)c3NC3=C(C(=O)CC(C)(C)C3)C2c2ccc(OCc3ccccc3)cc2F)nn1C +Cc1nc(C)c(-c2ccc(C34CCC(CC(=O)O)(CC3)CC4)cc2)nc1C(N)=O +COc1ccc(C(C)(NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 +COc1cccc2c1CCCC2CCCN1CCN(CCCC2CCCc3c(OC)cccc32)CC1 +O=C(c1ccccc1)c1sc(NCc2ccc(F)c(F)c2)nc1-c1ccco1 +O=C(O)Cc1cc(CC(=O)O)cc(-c2ccc(C#CCO)s2)c1 +N#Cc1ccc(-c2ccc3c(c2)SC(=N)N2CCCN=C32)cc1 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CCC(CCNS(=O)(=O)c2cccc3c(N(C)C)cccc23)CC1 +CCCNc1ncc(-c2cc(-c3c(Cl)cc(OC4CCCC4)cc3Cl)nc(-c3cnccn3)n2)s1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)OCC(O)=C(C#N)c1nc2ccccc2[nH]1 +Fc1cc(-c2ccncc2)cc(-n2nnc(-c3ccccn3)n2)c1 +COc1ccc2c(c1)CC(C(=O)Nc1ccc(-c3cn[nH]c3)c(OC)c1)CO2 +Cn1c(=N)n(CC(=O)c2ccc(Cl)cc2)c2cccc(Cl)c21 +N#CC1CCN(c2nccnc2OC2CC(Nc3ccc4ccccc4n3)C2)CC1 +CC1Cc2c(Br)cccc2N1C(=O)Cc1nc(N2CCOCC2)cc(=O)n1C +CN(Cc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +COc1ccc2[nH]c(C(=O)O)c(CCN3C(=O)c4ccc(C(=O)O)cc4C3=O)c2c1 +CCc1c(NC(=O)NC(C)c2ccccc2)ncc2c(-c3ccnc(C)c3)n[nH]c12 +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(F)cn3)CC2)CC1c1ccc(Cl)c(F)c1 +Cc1cccc(Nc2ccnc(Nc3ccc(N4CCN(C)CC4)cc3)n2)c1 +Cc1nc2c(N)ncnc2n1C1OC(CN(C)CCCCON)C(O)C1O +CCOC(=O)Oc1c(-c2ccc(Cc3ccc(OC(F)(F)F)cc3)cc2)c(C)nc2ccccc12 +Cc1c(C)c2ccc(OCc3ccc(F)c(F)c3)cc2oc1=O +COc1nc(N)nc2c1ncn2C1OC(CO)C(O)C1C#N +CC12CCC(O)CC1CCC1C2CCC2(C)C(C=CC=NOCCN)CCC12O +COc1ccc(CCN(CCCc2cccc(Br)c2)CCc2ccc3c(c2)OCO3)cc1OC +CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2)s1 +Cc1ccc(CCCCNC(=O)n2c(=O)oc3ccccc32)cc1 +COc1ccc(Cn2c(N3CCC(N(C)C)C3)nc3ccccc32)cc1 +CC(=O)NC(CSC(=O)Nc1ccc(F)cc1)C(=O)O +Nc1ncc(S(=O)(=O)NCCOc2ccc3c(c2)C(C2(c4ccc(Cl)cc4)CCC2)NCC3)cn1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccccc1O +COc1ccc(CN2CCC(NC(=O)CNC(=O)c3cc(C(F)(F)F)ccc3N)C2)cc1 +CCN1C2CCC1CC(OC1c3ccccc3CCc3ccccc31)C2 +Cn1cc(-c2cccc(-n3ncc4cc(C(C)(C)C)ccc4c3=O)c2CO)cc1C(N)=O +c1cc(OCCCCCOc2cccc(C3=NCCN3)n2)nc(C2=NCCN2)c1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2C)nc1-c1ccccc1 +Cc1n[nH]c(CN2C(=O)C(NC(=O)c3cc4cc(Cl)ccc4[nH]3)Cc3ccccc32)n1 +CC(C)(C)c1nc(N2CCN(CCCSc3nccc(O)n3)CC2)cc(C(F)(F)F)n1 +C=CCC(CC=C)(COc1cccc(CN(CC)CC=CC#CC(C)(C)C)c1)OCc1ccsc1 +Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(OCC4CCOC4)cc32)cn1 +O=c1c(CNc2nc3ccccc3s2)cn(-c2ccccc2)c2cc(Cl)ccc12 +COc1ccc(Nc2ncc(CN3CC[S+]([O-])CC3)cc2-c2nc(C)nc(N)n2)cn1 +CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2F)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 +CN1C(=O)Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3F)cc21 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+CN1C(=O)CCC2=C1C1Oc3c(O)ccc4c3C13CCN(C)C(C4)C3(O)C2 +COc1ccc2c(OCc3nnc4c(F)cc(-c5cnc(C)s5)cn34)ccnc2c1 +COc1ccccc1C(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +Cn1cc(-c2ccc3nnc(Sc4ccc5ncc(N6CCCNCC6)cc5c4)n3c2)cn1 +CCc1c(CC2CCCCC2)n(COCc2ccccc2)c(=O)[nH]c1=O +CS(=O)(=O)Nc1ccc(OCC(O)CNCCc2ccccc2Cl)cc1 +COc1ccnc2c1nc(CCn1c(=O)n(C)c3c(C)ccnc31)n2-c1ccccc1 +Cc1nc(C)n(-c2cc(C3CC3c3nc4ccccc4n3C)nc(NC(C)C)n2)n1 +CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCc2ccc(N=[N+]=[N-])cc2)CC1 +CSc1nc(-c2ccccc2)nn1C(=O)c1ccc(C)cc1 +COC(=O)c1c(NC(=O)CSc2ccccc2N)cnn1CCc1ccccc1 +N#CC(Cc1cccc(OCC(=O)O)c1)c1nc(-c2ccccc2)c(-c2ccccc2)o1 +Cc1[nH]nc2c1C(c1cc(N3CCOCC3)cc(C(F)(F)F)c1)(C(C)C)C(C#N)=C(N)O2 +Cc1ncn(C)c1CNc1ccc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1 +Cc1nc(NC(=O)N2CCCC2C(N)=O)sc1-c1ccc(S(C)(=O)=O)cc1 +CCCC1CC(=O)C2=C(C1)NC(C)=C(C(=O)OCC(C)C)C2c1ccc(C(C)(C)C)cc1 +NS(=O)(=O)Oc1ccc(-c2cccc(Cn3cncn3)c2)cc1 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1ccc2c(c1)OCO2 +Cc1sc2ncnc(Nc3c[nH]nc3C(=O)Nc3ccc(CN4CCOCC4)cc3)c2c1C +O=C(Nc1ccc(OC(F)(F)F)cc1)N1CC2CCN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1cccc(I)c1 +Nc1c(C(=O)NCC(O)(CN(CCO)C(=O)c2c(F)cccc2F)C(F)(F)F)cnn1-c1ccc(F)cc1 +COc1nc(NS(=O)(=O)NCc2ccccc2)c(Oc2ccccc2OC)c(OCCOc2ncc(Br)cn2)n1 +N#Cc1ccccc1-c1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 +Brc1cnc2nc(-c3ccc(CN4CC(c5n[nH]c(-c6ccccn6)n5)C4)cc3)c(-c3ccccc3)cn12 +COc1ccccc1N1CCN(CCCN2C(=O)CC(=C3c4ccccc4-c4ccccc43)C2=O)CC1 +CC(C)C(NC(=O)c1cc(C(=O)N2CCCC2C)c2n1CCOC2)c1ccc(F)cc1 +C=C(Br)C(=O)Nc1ccc2c(c1)cc(C(=O)NCCCCCCNc1nsc3nc4ccccc4n13)n2C +NS(=O)(=O)c1ccc(C=C2C(=O)Nc3ccc(F)cc32)cc1 +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccccc3C)cc12 +COc1ccc(-c2cc(-c3ccc(C)cc3O)[nH]n2)cc1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cccc(N5CCC(N6CCOCC6)CC5)c4)nc23)cc1 +CN1CC2CC1CN2CCOC(c1ccccc1)c1ccccc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3nc(C(=O)N4CCN(C)CC4)ccc3OC)NC(=O)NC1=O)C2 +CCCc1cc(Nc2nc(NCc3cc(C)no3)ncc2Br)n[nH]1 +O=C1CCC2(Cc3ccc(Cl)cc3)Cc3cc(O)ccc3C2=C1c1ccc(OCCN2CCCCC2)cc1 +COCCNc1nc(C)c(-c2nc3c(C)nccc3s2)c(NC2CC(C(C)(C)O)C(O)C2O)n1 +OC1(c2ccc(-c3ccccn3)cc2)CN2CCC1CC2 +CC1(C)C(=N)NC2(c3cc(NC(=O)c4cnsn4)ccc3F)COCC2S1(=O)=O +CC(C)CCOC1CCN(Cc2ccc(-n3nc(C(=O)N4CCOCC4)c4c3-c3ccccc3S(=O)(=O)C4)cc2)C1 +Cc1cc(N=Nc2ccc(S(=O)(=O)Nc3ccc(Cl)cn3)cc2)cc(C)c1O +COc1ccc(-c2cc(NCC(C)O)c3ccccc3n2)cc1C +Cc1ccccc1Cc1nnc(N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c2c1CCC2 +CC(=Cc1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CS2 +CC(C)(C)OC(=O)N1CCCN(CC(=O)NC2C3CC4CC(C3)CC2C4)S1(=O)=O +COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csnn2)cc1 +O=C(NCC1(O)CCC1)c1cn(Cc2ccc(-n3cccn3)cc2)c2cccnc12 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4cc(OC5CCC(O)C5)ccn4)n3)ccc2[nH]1 +CS(=O)(=O)CC(=O)N(CCc1ccccc1)CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2 +COc1cccc(OC)c1OCCNC1COCC(c2ccccc2)(c2ccccc2)O1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)C4CCC(C)(C)N4)ncn3)cccc2s1 +Cc1cccc(C)c1CNc1ncnc2c(C)c(C)[nH]c12 +CC1CCC(C(=O)N(c2ccc(Oc3ncccc3C(F)(F)F)cc2C(=O)O)C(C)C)CC1 +Clc1ccc(-[n+]2nc(-c3ccc(-c4ccccc4)cc3)nn2-c2ccccc2)cc1 +COc1cccc(-n2c(=O)n(CC(=O)Nc3ccc4c(c3)CC3(C4)C(=O)NC(=O)N3C)c3ccccc32)n1 +CC1CCC(N(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)c2nc(C#N)ncc2Br)C1 +CC(C)n1nc(-c2cnc(N)c(C#N)c2)cc1C1CCN(C2COC2)CC1 +c1ccc(C2(CCc3nc(-c4ccccn4)no3)CCCCC2)cc1 +CC(C)=CCCC1(C)CCCC2(C)C(Cc3cc(C(=O)O)ccc3O)C(C)=CCC12 +COC(=O)C(CCSC)N(C(=O)c1ccccc1)C1CCN(Cc2cncn2Cc2ccccc2)CC1 +O=C(O)c1cc(F)cc(-c2cccc(COc3ccc4c(c3)CN(C3CCCC3)C4=O)c2)c1 +Cc1ccc(C=CC(=O)N2CCN(c3ccc(C(=O)Nc4ccccc4N)cc3)CC2)cc1 +O=C(Nc1cccc(-c2ccccc2)c1)C1CC(=O)N(C2CC3CCC2C3)C1 +Cc1cc(C)c(Nc2nc3ccccc3n2-c2cc(N)ncn2)c(C)c1 +COc1nn2cc(-c3cc4ccc([N+](=O)[O-])cc4o3)nc2s1 +CC(=Cc1csc(C)n1)C1CC2OC2CCCC(C)C(O)C(C)C(=O)C(C)(C)C=CC(=O)O1 +COc1cccc2c1OCC(C(=O)N1CCCC1c1ncc(-c3cccnc3)[nH]1)=C2 +O=c1oc(-c2cccnc2Oc2ccccc2)nc2cccc(Cl)c12 +Cc1nocc1-c1ccc2[nH]nc(-c3cc(N4CCOCC4)ncn3)c2c1 +Clc1ccc(Cn2c(C=NNc3nc(N4CCOCC4)c4sccc4n3)nc3ccccc32)cc1 +COCc1cnc(N2CCC(C3CC3COCc3ccc(S(C)(=O)=O)c(F)c3)CC2)nc1 +Cc1ccc(NC(=O)c2cccc(N3CCOCC3)c2)cc1NC(=O)c1ccc(OCc2ccccn2)cc1 +Cn1ccc2cc(-c3ccc4oc(Nc5ccc(F)cc5)nc4c3)ccc21 +O=C(NCCN1CCC(Cc2ccccc2)CC1)C(c1ccccc1)c1ccccc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)N1CCOC2(CCN(C(=O)c3cc(Cl)ccn3)CC2)C1 +CCC(Nc1n[s+]([O-])nc1Nc1cccc(C(=O)N(C)C)c1O)c1cc(C(C)C)co1 +Cc1cnc(Nc2ccc(CN3CCN(C)CC3)cc2)nc1-c1ccc(F)c(Cl)c1 +O=C(Oc1cccc2cccnc12)c1cccc(S(=O)(=O)N2CCCCCC2)c1 +COCC(NC(=O)Nc1cc2[nH]nc(OC3CCC(C#N)CC3)c2cn1)c1ccccc1 +CN1C2CCC1C(C(=O)N1CCCCC1)C(c1ccc(Cl)cc1)C2 +Cc1n[nH]cc1-c1nncc2nc(Nc3ccc(F)cc3F)ccc12 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(N2CCOCC2)cc1Cl +Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OC(C)C(F)(F)F)c(C3CC3)cn2)no1 +CC(NC(=O)OC(C)(C)C)C(=O)Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 +CCN1C(=O)c2nc(Br)n(Cc3ccc(OC)cc3)c2N2CC(Cc3ccccc3)N=C12 +CC1(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4Cl)nc23)CCNCC1 +CC(C)N1CCCCC1c1nc2c(C(N)=O)cccc2[nH]1 +Cc1cccc(C)c1Nc1ncc(-c2ccc(N(C)C)cc2)n2cncc12 +CCOC(=O)c1[nH]c2ccc(Br)cc2c1Cc1cc(O)c(OC)c(OC)c1 +O=S1(=O)CCOc2ccc(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)cc21 +CNCCCCNCCCCNCc1c2ccccc2c(CNCCCCNCCCCNC)c2ccccc12 +COc1cccc(C2OC(CC(=O)N(C)CC(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC +COc1cc(C=C2CCCC(=Cc3ccccc3[N+](=O)[O-])C2=O)cc(OC)c1OC +CC(OCc1cc(Cl)cc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1)C(F)(F)F +N#Cc1nn(-c2cccc(C(F)(F)F)c2)c(=O)n(CCN2CCCCC2)c1=O +CC1(C)OC(=O)Nc2ccc(-c3cccc(C#N)c3)cc21 +Cc1ccc(S(=O)(=O)N(C)c2ccccc2N(C)S(=O)(=O)c2ccc(C)cc2)cc1 +CCCC(NC(=O)N1CC(=NOCC(F)(F)F)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 +O=S(=O)(Nc1ccc2[nH]cc(CC3CCCN3)c2c1)c1ccc(I)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC4CC4)c(F)c3)C2)cc1 +CCOc1cc(CN2CC3(CC(c4cccc(C(=O)O)c4)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +COc1cc(Nc2nc3n(n2)CCC(C)(O)CC3c2ccc(F)cc2)ccc1-n1cnc(Cl)c1 +COc1cc(N2CCN(C3CCN(c4cccc5c(OC)cc(C(F)(F)F)nc45)CC3)CC2)c2ncccc2c1 +O=C(Nc1nc2ccc(C3(O)c4ccccc4C(=O)N3c3cccc(Cl)c3F)cc2[nH]1)OCC1CCCN2CCCCC12 +Cc1nc2cnccc2n1Cc1ccc(S(=O)(=O)N(C)C(CC(C)C)C(=O)NCc2cccc(N)c2)cc1 +O=c1[nH]c(Cc2ccccc2)nc2sc3c(c12)CCCCC3 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+Cc1ccc(Oc2ccc(C(=O)NCCN3CCCC3)cc2NC(=O)Nc2ccc(-c3ccccc3)cc2)cc1C +CC1(c2cccc3ccccc23)NC(=O)N(CCCn2ccnc2)C1=O +N#Cc1c[nH]c2nc(N)nc(-c3ccc(CO)cc3)c12 +COc1cc2c(cc1OS(N)(=O)=O)CCC1C2CCC2(C)C(=O)CCC12 +COc1cc(-c2ccccn2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +Cc1cc(C)nc(OCCCn2c3c(c4cc(C#N)ccc42)CCCC3)n1 +CCNC(=O)Nc1cc2c(-c3ccnc(C)c3)ccc(COC(=O)N3CCN(C)CC3)c2cn1 +O=c1cc(-c2ccccc2)oc2ccc3c(c12)OCC=C3 +CS(=O)(=O)c1ccc(-c2[nH]c3ncnc(NCC4CCCO4)c3c2-c2ccccc2)cc1 +CC(C)C(c1ccc(-c2ccccc2)nc1)n1ccnc1 +O=C(O)Cc1sc(Nc2cccc3ccccc23)nc1-c1ccc(Cl)cc1 +CNC(=O)C1OC(n2cnc3c(NC)nc(C#Cc4ccccn4)nc32)C(O)C1O +CC(C)C(CO)NCc1nc(N2CCc3ccc(C(F)(F)F)cc3C2)ccc1F +CCCN1C(=O)C(NC(=O)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)N=C(C2CC2)c2ccccc21 +COc1ccc(CNCC2(N3CCN(C(=O)C4CN(C(C)C)CC4c4ccc(Cl)cc4)CC3)CCCCC2)cc1F +CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(C(=O)NCCOCCO)c2)n1 +CC1CCCCC1Oc1nc(N)c2c(=O)ccn(C3CCCC3O)c2n1 +COc1cc(F)c(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c(F)c1 +CNC(=O)C1CCN(S(=O)(=O)CC2CCC(N(C)c3ncnc4[nH]ccc34)CC2)CC1 +CN1C(=N)NC(=O)C1=Cc1c[nH]c2cccc(Br)c12 +CN1C(=O)Nc2cccc(Cl)c2C12NC(=O)NC2=O +N#Cc1cc(-c2ccnc(Nc3ccc(NC(=O)CN4CCOCC4)nc3)n2)cnc1N1CCC(F)C1 +CCn1c(=Cc2sc3ccccc3[n+]2C)sc(=CC=c2nc3c(o2)=CC=CN3C)c1=O +NC(=S)NN=C(c1cccc(Br)c1)c1cccc(F)c1F +COC1CCN(c2ccc(C(=O)NCc3cn(-c4ccccc4)c4cc(Cl)ccc4c3=O)cn2)CC1 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cc(Cl)cc(C(F)(F)F)c2)cc1 +COc1cccc(CN(CCN2CCCC2)C(=O)c2cc3ccc(-c4cn[nH]c4)nc3n2C)c1 +OC1CCCc2nc3cc(Cl)ccc3c(NCc3ccc(F)cc3)c21 +COc1cc(OCc2nnc(-c3ccccc3)s2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +OC(CN1CCC(c2nnn3cnc4[nH]ccc4c23)CC1)c1ccc(C(F)(F)F)cc1 +NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1cc(Cl)ccc1N +c1ccc(-c2nn3c(c2-c2ccnc4ccccc24)CCC3)nc1 +CCCOc1ccc(Oc2ccc(-c3ccc(C(C)NC(=O)CC)cc3)cn2)cc1 +Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2cccs2)C3)c1-c1ccc(C(F)(F)F)cc1 +Cc1ccc(C(CC(N)=O)NC(=O)CCCOc2c(CCCO)c(-c3cccnc3)nn2-c2ccc(Cl)c(Cl)c2)cc1 +NC(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(c1ccccc1)c1ccccc1 +COC(=O)C1C(CO)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +NS(=O)(=O)c1cccc(N=Nc2ccc(O)cc2)c1 +Nc1nc(Nc2ccc(N3CCOCC3)cc2)nn1-c1ccccn1 +CC1CCC(C(C)C)C(NC(=O)Oc2ccc(Cl)cc2)C1 +O=C(NO)c1ccc2c(c1)CC(NS(=O)(=O)c1cccnc1)CC2 +CCCCN1CCc2cc(Cl)c(O)cc2C(c2ccccc2)C1 +O=C(Nc1nc2cccc(-c3ccc(CN4CCCCC4)cc3)n2n1)C1CC1 +CCCCC(=O)NC(CCC(=O)N1CCC(CCCC2CCNCC2)CC1)C(=O)O +c1ccc2c(c1)CCN=C(NCc1ccc3c(c1)OCO3)N2 +CCOc1n[nH]c2cc(NC(=O)NC(c3ccccc3)C(C)(C)OC)ncc12 +COc1ccccc1-n1nc(OC2CCC(NC(=O)C(F)(F)F)CC2)cc1-c1ccc(Cl)cc1 +CC(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2)c(-c2ccnc(N)n2)s1 +O=C1NC(=O)C(c2cnc3ccncn23)=C1c1cn2c3c(cccc13)CN(C(=O)N1CCOCC1)CC2 +N#CC1CCCN1C(=O)CNCCC(=O)N1CCc2cc(F)ccc2C1 +COc1cccc(CNC(=O)c2cc3ccc(-c4ccncc4)nc3[nH]2)c1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4c[nH]nn4)ncc23)ccn1 +Nc1nn2cccnc2c1C(=O)Nc1cn(C2CCN(Cc3ccccc3)CC2)nc1-c1cc(Cl)ccc1OC(F)F +Cn1cc(-c2c(F)cncc2C=CC(=O)Nc2ccc(CN3CCOCC3)cc2)cn1 +Cc1ccc(C(=O)Nc2cccc(N3CCOCC3)c2)cc1-c1ccc2nc(N)[nH]c(=O)c2c1 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+O=C(CCCCN1CCCCCC1)Nc1ccc(-c2cccnc2)cc1 +O=C(CN(Cc1ccc([N+](=O)[O-])cc1)S(=O)(=O)c1cc(Cl)ccc1Cl)NO +COc1ccc(C)cc1S(=O)(=O)N1CCCc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 +CC1(C)CC(=O)c2sc(N3CCOc4ccc(Br)cc43)nc2C1 +CNc1nnc(-c2ccc3[nH]cc(-c4cccc(OC(C)C)n4)c3c2)o1 +O=C(NC1CCCCN(CCc2ccc(F)cc2)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +Cn1nnc(-c2ccc(Nc3nccc(-c4cc(C#N)cc(N5CCOCC5)c4)n3)cc2)n1 +Cc1ccc2cnc(N(Cc3ccc(OC(F)(F)F)cc3)S(=O)(=O)c3ccc(C(=O)O)cc3)c(C)c2c1 +Nc1ncnc2c1ncn2C1CC(OP(=O)(O)O)C2(COP(=O)(O)O)CC12 +CCNC(=O)Nc1ccc(-c2nn(CC)cc2-c2ccnc3[nH]c(-c4cccc(CN(C)C)c4)cc23)cc1 +Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C#N)nc1N2 +CC1CC(c2ccc3nc(-c4ccccc4)oc3c2)=NNC1=O +CCCCCCCCCCCCCCCNOC(=O)CC1COC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1 +CNS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(OCC(C)C)c(Cl)c2)cc1F +CC(C)(O)c1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(Br)cc2)sc2ccccc12 +O=C(Nc1c(Cl)c[n+]([O-])cc1Cl)C(=O)c1cc(Cc2ccc(O)cc2)n2ccccc12 +COc1ccc(-c2n[nH]c3c2C(C2CCCCC2)N(Cc2cc(C)on2)C3=O)cc1 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+Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCNC(C)(C)C +CCC(C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N3CCCC3=O)cc1)C2c1ccc(Cl)cc1 +Cc1ccc(-c2cc(Br)ccc2OCc2c(F)cccc2C(F)(F)F)n1-c1cccc(C(=O)O)c1 +COc1cnc2c(Nc3ccc(F)c(C4(CF)CC(C(F)(F)F)OC(N)=N4)c3)nccc2n1 +CC1CN(c2ccccn2)CCN1C(=O)C12CC3CC(CC(C3)C1)C2 +Cc1nc(C=O)c2c(n1)N(Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)CC2 +Cn1cc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2(C)C +O=C(C=Cc1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C2)NS(=O)(=O)c1cccc(Cl)c1 +CN1CCN(CCCN2CCC3(N4CCN(C)CC4)CC(c4ccccc4)C2C(c2ccccc2)C3)CC1 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCC3CCC(=O)N3)cc12 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1CC2OCC(OC)C2O1 +O=C(CCCN1CCN(CCC2Cc3sccc3C2=O)CC1)c1ccc(F)cc1 +O=C(Cc1ccc(F)cc1)Nc1nc(-c2ccncc2)cs1 +CCOC(=O)C(=Cc1cc(=O)c(OC)co1)C(=O)OCC +CC(=O)Nc1cc(Cl)ccc1C=CC(=O)N1CC(C)N(Cc2ccc(F)cc2)CC1C +CCOC(=O)C(C)(C)Oc1ccc(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)cc1 +COc1cc(NC(=O)c2ccc(C(C)(C)C)o2)ccc1-c1cnco1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc3ncccc3c2)n1 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+Cc1cc(CC(CC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)c2ccccn2)cc2cn[nH]c12 +Cc1nn(-c2cccc(Nc3ccc4c(c3)c(C(=O)C(F)(F)F)cn4C)n2)cc1CN1CCC(O)C1 +O=c1ccc(-n2cnc3ccccc32)nn1CCCCN1CCN(c2ccccc2Cl)CC1 +COc1ccc(N(C)Cc2cnc3nc(N)nc(N)c3c2C)cc1 +O=C(COc1ccc(C(F)(F)F)cc1)NNC(=S)NCCCCC1CCCCC1 +CC(C)N(Cc1ccccc1)c1nc(O)nc(Nc2ccc3ncsc3c2)n1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCC(N4CCCC4C(=O)O)CC3)cc12 +COc1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1F +COCCN1CCN(c2ccc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)cn2)CC1 +Cc1ccccc1OC(=O)N1c2ccccc2Sc2ccccc21 +Nc1cc2[nH]c(C(=O)NCc3ccc(S(=O)(=O)c4cc(F)cc(F)c4)cc3)cc2cn1 +COc1ccc(Nc2ccnc3ccc(-c4ccc(S(=O)(=O)N5CCOCC5)cc4)cc23)cc1C +COc1ccc2cc3[n+](cc2c1OCCCCOc1ccccc1)CCc1cc2c(cc1-3)OCO2 +COc1cccc2c1CCCC2OCCN1CCN(C2CCCCC2)CC1 +O=C(NC(Cc1ccc(F)c(Br)c1)C(=O)O)c1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 +CC(c1nc2ccccc2c(=O)n1C)N1CCN(C(=O)C(C)(C)C)CC1 +CC(=O)Nc1cccc(N2CCN(CCCCNS(=O)(=O)C(C)C)CC2)c1 +COc1ccc(CC(=O)Nc2nc3nn(C)c(SC)c3c3nc(-c4ccco4)nn23)cc1 +CC(C)c1ccc(CNC(=O)c2cn3cc(-c4ccc(C5CCC(CC(=O)O)CC5)cc4)ccc3n2)cc1 +CCOCC1CC2C(C)SC(N)=NC2(c2ccc(F)cc2F)CO1 +[C-]#[N+]c1cccc(C2CN3CCN(C(=O)C4CCc5nc(-n6cnnn6)ccc54)CC3CO2)c1C +c1cc(OCc2ccc(COc3cccc(C4=NCCN4)c3)cc2)cc(C2=NCCN2)c1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCNC2=O +CC(NC(=O)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1)c1ccc(F)c(Cl)c1 +O=C(CCCc1ccc(N(CCCl)CCCl)cc1)NN=CCN1C(=O)C=CC1=O +CCCOC(=O)C1=C(Nc2ccc3ccccc3c2)SCC1=O +Cc1ccc(C(=O)Nc2nc(-c3ccccn3)cc3ccccc23)cc1C +Cc1c(-c2ccc(Cc3ccc(OC(F)(F)F)cc3)cc2)[nH]c2cc(O)ccc2c1=O +CC1CNC(=O)c2[nH]c3ccc(C(=O)Nc4nc(C(=O)NCCO)cs4)cc3c21 +Cc1n[nH]c2ccc(-c3cc(NC(CO)c4ccccc4)cnc3-c3cccc(F)c3O)cc12 +CC(C)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)c1nc(N)no1 +COc1ccc(NC(=O)C=C2c3nc4ccccc4cc3C(=O)N2c2ccc(Cl)cc2)cc1 +O=C(Nc1c(Cl)cncc1Cl)c1ccc(CO)n2nc(C(F)(F)F)cc12 +COc1cc(-c2cc(=O)c3ccc(C)cc3o2)ccc1O +O=C(NCc1cccnc1)c1ccc(N2CCC3(CCc4ccccc4O3)CC2)nn1 +O=C(O)c1csc(C2CCC3C(CC(O)C3COc3ccccc3F)O2)n1 +Oc1cccc(-c2cc(N3CCOCC3)nc(NCc3ccncc3)n2)c1 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+CC1(COc2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc2C2CC2)CC=CCC1 +CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 +Cc1nc2c(nc1-c1cc3nc(N4CCCC4)cc(NC4CCC(C)(O)CC4)n3n1)CCCO2 +O=C(c1csc(Cc2n[nH]c(=O)c3ccccc23)c1)N1CCN(C(=O)c2ccccn2)CC1 +CC(=O)c1ccc(N2CCN(Cc3ccccc3)CC2)cc1 +CCOC1(C)CN(c2cc(-c3cnc(N)c(OC(F)F)c3)nc(N3CC4CC3C4)n2)C1 +Cc1cc(C)c(C(=O)C=Cc2ccc(O)c(O)c2)c(C)c1 +Cc1cc(C)c(NC(=O)c2ccc3nc(Nc4cc(C)nc(C)n4)sc3c2)c(C)c1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccc2N(C)C)c1C +Fc1ccc(SCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1 +CCC(C)N1CCN(C(=O)C=Cc2ccc(Br)cc2)CC1 +CC(c1ccccc1)C(O)C=CC1C2CCC(O2)C1CC=CCCCC(=O)O +COc1ccc(-c2oc3ncnc(NCCCN4CCOCC4)c3c2-c2ccc(OC)cc2)cc1 +Oc1ccc2c(c1)C13CCN(CC4CC4)CC1(C2)Cc1c([nH]c2ccccc12)C3 +O=C(NCC(=O)N1CCCCC1)c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F +CCc1c(C(=O)O)cccc1-c1cc(C)cc(Nc2nccc(C(F)(F)F)n2)c1 +O=C(CCCN1Cc2cc3c(Nc4cccc(Br)c4)ncnc3cc21)N1CCOCC1 +CC(C)(C)CCN1C(=O)C(C2=NS(=O)(=O)c3ccccc32)=C(O)C1C(C)(C)C +CC(CCn1ccc(C2=CCCCC2)cc1=O)(C(=O)NO)S(C)(=O)=O 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+COc1cc2[nH]c(-c3cccc(Oc4ccccc4)c3)c(C(=O)OCCO)c(=O)c2cc1F +CCCCCN(CCCCC)C(=O)Cc1cc(-c2ccccc2)no1 +CNc1nc(C2c3ccc(F)cc3CN2C(=O)C(O)C(O)C(=O)NC(C)c2ccc(-n3cccn3)cc2)cs1 +O=C1CC2(CCN(CCc3ccccn3)CC2)Oc2ccccc21 +COCC(=O)N1CCN(c2nc(C)c3cc(NC(=O)COc4ccc(Cl)cc4)ccc3n2)CC1 +CCC(O)(CC)c1ccc2cc(-c3n[nH]c4cc(-c5ccccc5)sc34)[nH]c2c1 +CC(c1ccc(C(C)(C)C)cc1)N1CCC2(CCC(O)CC2)OC1=O +Cc1ccc(C(=O)c2ccc(C(=O)c3ccc(C(=O)O)cc3)cc2)cc1 +Cn1c(=N)n(CC(=O)c2ccc(C(C)(C)C)cc2)c2ccccc21 +Cc1ccc(-c2nn(CCCCCCCN3CCN(c4cccc(C(F)(F)F)c4)CC3)c(=O)c3ccccc23)cc1 +CCC(O)Cn1c(C)c(C(=O)Nc2ccc(Oc3ccnc4cc(OC)ccc34)c(F)c2)c(=O)n1-c1ccccc1 +CC(=O)NC(C)c1ccc(CN2CCc3cc(OCCC(F)F)ccc3C2)cc1 +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1CCOC(=O)NCCCn1ccnc1 +COc1cc(Br)c(S(=O)(=O)Cc2ccc(Cl)c(OC3CCN(C)C3)c2)cc1OC +CN(C)C(=O)c1ccc(N(C)C(=O)c2ccc(O)cc2O)cc1 +O=C(NCC(NS(=O)(=O)c1cccnc1)C(=O)O)c1ccc2c(c1)C(=O)N(CCC1CCNCC1)C2 +CS(=O)(=O)c1ccc(N2N=C(C(F)(F)F)CC2c2ccc3ccccc3c2)cc1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(-c3c[nH]cn3)c2)cc1 +CN1C(=O)NCc2c(NC(=O)NC3CCOc4c(OC(F)(F)F)cccc43)cccc21 +Oc1nc(CCCN2CC=C(c3ccccc3)CC2)nc2cc(Cl)ccc12 +O=C(O)c1cccc(Oc2cccc(CCNCC(O)c3cccc(Cl)c3)c2)c1 +CN(C)Cc1cn2c(-c3ccncc3)c(-c3ccc(F)cc3)nc2s1 +Cc1ccc(OCC(=O)Nc2ccc(OCC(=O)O)c(F)c2)cc1 +CN(C)CCCON=C1c2ccccc2-c2nc3c(CN4CCC(N5CCCCC5)CC4)cccc3nc21 +CCCCOc1ccc(C(CC)NC(=O)Oc2ccccc2)cc1 +CCCc1ccc(CSCC(NC(=O)C(C)CS)C(=O)O)cc1 +Cc1cc(NCCCNc2ccnc3cc(Cl)ccc23)nc(NCCCO)n1 +CN1Cc2c(C3=CCN(S(C)(=O)=O)CC3)[nH]c3nccc(c23)-c2cccnc21 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(c3ccc(F)cc3)CC1)CC2 +Cc1ccc2c(c1)C(OC1CC3CCC(C1)N3C)c1ccccc1CC2 +O=C1NN=C(c2ccc3nc(-c4ccc(OCCN5CCOCC5)cc4)oc3c2)C2CC12 +CC(c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1)N1CCOCC1=O +COc1ccc(C)cc1-c1cc(OC)c(-n2c(=O)ccc3cc(S(=O)(=O)Nc4ccon4)ccc32)cc1F +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CC(F)(F)C3)cc2F)cn1 +COc1ccc(C2c3nc(CC(C)C)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)cc1 +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3c(C)ccc4[nH]nc(C)c34)nc(N3CCC3C)c2C1 +O=P(O)(O)OCCCC1OC(CO)C(OP(=O)(O)O)C(OP(=O)(O)O)C1O 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+CC(C)(C)n1ncc(OCc2ccc(OCCCF)cc2)c(Cl)c1=O +COC(=O)c1ccc(C(C)n2[nH]c(=O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)cc1 +N=C(N)c1ccc(-c2cc(-c3ccc(C(=N)N)cn3)no2)cc1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccccn3)[nH]c2c1 +COc1ccc(CN2c3ccc(OC(C)=O)cc3C(C)=CC2(C)C)cc1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(NC4CCC(CN(C)C)CC4)c3c2)cc(Cl)c1O +CC(C)N1CCc2nc(C(=O)Nc3cc(C(=O)O)ccc3CNC(=O)c3ccc(Cl)s3)sc2C1 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4CSc4nncs4)C(C2)N(CC2CC2)CCC315 +COc1ccc(OC)c(-c2ccc(O)c(CNCC3(N4CCCCC4)CCCCC3)c2)c1 +Cc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(C(C)(C)C)c2)c1 +COc1ccc(OCC(O)CN2CCN(C(CNC(=O)c3ccccc3OC)c3ccccc3)CC2)cc1 +O=C(O)c1ccc(N2CC3(CCN(Cc4cc(OC(F)(F)F)ccc4-c4ccc(F)c(F)c4F)CC3)OC2=O)cc1 +Cn1c(=O)c2cn(Cc3cccc4ccccc34)cc2n(CC2CC2)c1=O +CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c(C=CC(=O)NS(=O)(=O)c3ccc(F)c(F)c3)cccc21 +O=C(CSC(=S)NN1CCSCC1)NCc1ccc2c(c1)OCO2 +CC1(C(=O)NC2C3CC4CC2CC(O)(C4)C3)CCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +O=C(Nc1cnc(-c2ccncc2)c(-c2ccco2)n1)C1CCC1 +O=C(NCc1ccc(Cl)cc1Cl)c1ccc(OCC(F)(F)F)nc1 +O=C(Cc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +Cc1cccc2oc(-c3cccc(CC(O)C=CC4CCC(=O)N4CCSc4nc(C(=O)O)cs4)c3)nc12 +Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1Cc1cccc(C(=O)N(C)C)c1 +CN(c1ncccc1CNc1c(C(F)(F)F)cnc2[nH]c(-c3ccc(Br)cc3)nc12)S(C)(=O)=O +COc1ccc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)OCC3(F)F)c2)nc1 +O=S1(=O)c2cccc3cccc(c23)N1CCCCN1CC=C(c2ccccc2)CC1 +CC1=CC(=O)N(Nc2nc(-c3cccs3)nc3sc(C#N)c(C)c23)C1=O +CC(C)Oc1ccc(-c2cc3c(NC(P(=O)(O)O)P(=O)(O)O)ncnc3s2)cc1 +CCCCOP(=O)(CC(CCc1ccccc1)OP(=O)(OCCCC)OCCCC)OCCCC +Cc1n[nH]c(NCC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)c1-c1ccccc1 +Nc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1 +Cc1nnc(CNc2cc(OCC3CC3c3ccc(Cl)cn3)nn(C)c2=O)s1 +COc1ccccc1-n1c(-c2cccc(O)c2)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 +FC(F)Oc1ccc(-c2ccc3c(c2)CN2CCC3(c3ccc(Cl)cc3)C2)nn1 +CCC(NC(=O)c1cc(C(=O)NCc2nccs2)n2c1COCC2)c1ccccc1 +COc1cc(C=Cc2cc(OC)c(OC)c(OC)c2)cc(NC(=O)c2cn(Cc3ccc(F)cc3)nn2)c1OC +O=C(NC1CCCOC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 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+CNC(=O)C12CC1C(n1cnc3c(NCc4cccc(Cl)c4)nc(C#CCCCC(=O)O)nc31)C(O)C2O +c1ccc2c(c1)N=C(N1CCN(CC3CCCO3)CC1)c1ccccc1S2 +O=C(CCS(=O)(=O)N1CCC(Oc2ccc(-n3ccnc3)cc2)CC1)NO +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(C)cc3C)ccnc21 +COc1ccc(C2CN(CCc3ccc(OC)c(OC)c3)CC2CC(=O)Nc2cccc(Cl)c2)cc1 +CN1Cc2c(C3=CCN(C4CCC(C(=O)O)CC4)CC3)[nH]c3ncc(F)c(c23)-c2ccccc21 +Cc1cccc(-c2[nH]c(CNc3cc(C#N)ccc3CN3CCCC3)nc2-c2ccc3ncnn3c2)n1 +CC(CN1CCc2cc(F)ccc21)NC(=O)OC(CC1CCCCC1)C(=O)N1CCOCC1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3cnc(OC4CC4)cn3)cs2)CO1 +CCCCc1cn(CCCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1 +CCn1c2ccccc2c2cc(CNc3cnc(-c4ccc(CC(N)C(=O)O)cc4)cn3)ccc21 +CCOC(=O)CCCOc1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC2CCC1C2 +CCCCOc1ccc(S(=O)(=O)N(CC(=O)NN=C2C(=O)Nc3ccccc32)c2ccc(Cl)cc2)cc1 +Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)CCCC2=O +Cc1nc(NC(C)c2cc(F)cc(-c3cnc(Cl)c(N)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 +O=C(O)CCCc1nc(CCCc2ccc3c(n2)NCCC3)no1 +CN(C)CC(C)(C)COc1ccc(NC(=O)Nc2cccnc2Oc2ccccc2C(C)(C)C)cc1 +ClC(Cl)(Cl)c1nc(Nc2ccc(Br)cc2Br)c2ccccc2n1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC3CN(c4nccc(-c5ccccc5)n4)CC3C2)c1 +CN(C)C(=O)c1coc(C(CCCC2CCCCC2)CC(=O)NO)n1 +CC(=NNS(=O)(=O)c1cc([N+](=O)[O-])ccc1C)c1c(C)nc2ccc(Br)cn12 +CC1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CS(=O)(=O)C2(CCOCC2)C(=N)N1 +O=C1Nc2ccc(F)cc2C1=C1Nc2ccc(O)cc2C1=NO +Cc1cc(OCC2CCC(C(=O)O)C2)c(NC(=O)Nc2cnc(C#N)cn2)cc1Cl +CC(O)(COc1ccccc1F)C(=O)N1CCc2c(C#N)cccc21 +CCN(CC)c1ccc(N2CCN(Cc3ccc(F)cc3Cl)C(=O)C2=O)c(C)c1 +N#Cc1ccc2[nH]c3c(c2c1)CCc1c[nH]nc1-3 +CC(C)CN(c1cccc(C(F)(F)F)c1)S(=O)(=O)c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1 +NCCN1C2=C(C(=O)Nc3ccccc3F)C(=O)CCN2c2ccc(F)cc21 +CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2C3CCCC32)cc1F +CCC(CC1(C)CC(CC)C(CC(=O)OC)OO1)C(=O)OC +O=C(c1ccc(I)cc1NS(=O)(=O)c1cccc2nccnc12)N1CCOCC1 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NCCC(=O)O)cc2C)ncn1 +CCCS(=O)(=O)N1CCN(C2(CNC(=O)c3c(F)cccc3F)CCC(F)(F)CC2)CC1 +COc1cc(F)cc(OC)c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)cc1 +N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)Cc3ccccc3C(=O)O)c(Cl)c2)cc1 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+Cc1ccccc1-c1ccc(OC(Cc2ccccc2)C(=O)O)cc1 +Clc1ccc(-c2ccc(C3=NOC(c4ccc(-c5cncnc5)cc4)N3c3ccc(N4CCNCC4)cc3)o2)cc1 +CCCCCCCCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O +CCOC(O)=C1C(COCCNC(=O)c2cccnc2)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CNC1)C2c1ccc(Sc2nc3c(F)cccc3[nH]2)o1 +CC(C)(O)C1CCN(c2nc(NC3CCCNC3)c(-c3ccc4ccccc4n3)c(=O)[nH]2)C1 +CCC(=NNC(=O)c1cc2ccccc2cc1O)c1cc2c(F)c(F)c(F)cc2[nH]1 +C1=C(c2c[nH]c3ncccc23)CCN(CCOc2cccc3ncccc23)C1 +CC1C=CC(=O)C(O)C(O)CC=Cc2cc(NCC(=O)O)cc(O)c2C(=O)OC1C +O=C(Cc1cccc(Br)c1)NC1CCN(Cc2ccccc2)CC1 +NC(=O)CC(NC(=O)C(N)CCCN=C(N)N[N+](=O)[O-])C(N)=O +CC(C)(C)C1CCC2(CC1)CN(c1cccc(OC(F)(F)F)c1)C(=O)N2Cc1ccc(C(=O)NCCC(=O)O)cc1 +CS(=O)(=O)CCNC1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)CC1 +COc1cccc(NC(=O)N2CCN(c3ncnc4[nH]cc(C)c34)CC2C)c1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCN(CCN4CCOCC4)CC3)[nH]c12 +Cc1cccc(-c2nc(C3CC3)ccc2CNC(=O)C(C)c2ccc(CNS(C)(=O)=O)c(F)c2)c1 +Cc1ccccc1OCC(O)CNC1CCC(NCC(O)COc2ccccc2C)CC1 +CC1CN(Cc2c[nH]nc2-c2ccc(C(N)=O)[nH]2)CCN1c1ccc(C(F)(F)F)cn1 +CCNC(=O)C1CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C(NC(=O)c2nc3c(s2)CN(C)CC3)C1 +CC(CN1CCN(C)CC1)NC(=O)CC1CNC(=O)c2cc(-c3cccc(Cl)c3)cn21 +O=C(Nc1ccc(C(=O)N2CC3C4CCC(C4)N3Cc3cc(Cl)ccc32)cc1)c1ccccc1F +CC1(C)OC(=O)C(Sc2ccccc2)=C1c1ccc(S(C)(=O)=O)cc1 +O=C1C(Cl)=C(N2C(=O)CCC2=O)C(=O)c2ccccc21 +COC1Cc2sccc2C2(CCN(Cc3ccc(F)cc3)CC2)O1 +O=C1C2=NCC3(CCCC3)CN2c2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc21 +CCN(CC)C(=O)Cc1c(-c2ccc(OCCF)cc2)nn2c(C)c(Cl)c(C)nc12 +O=C(Nc1ccnc(NC(=O)C2CC2)c1)c1c(Cl)cccc1Cl +CNC(=O)c1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 +O=C(O)c1cncc(-c2cccc(NCCNCC(O)c3cccc(Cl)c3)c2)c1 +CCOC(=O)c1cnc(N2CCN(C(=O)Nc3cccc(Cl)c3)CC2)c(Cl)c1 +NC(COc1cncc(-c2ccc3c(Cl)nccc3c2)c1)Cc1c[nH]c2ccccc12 +Nc1ccc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1 +Cc1cccc(-n2cnc3cc(C(=O)N4CCC(Br)CC4)ccc32)c1 +CP1(=O)OCC2(CCCC3(S(=O)(=O)c4ccc(Cl)cc4)c4c(F)ccc(F)c4OCC23)CO1 +O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccc(Cl)cc1)C3 +CCNC(=O)c1ccccc1CCC(SCC(CC)C(=O)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 +COc1cc(Nc2nc(-c3ccc4cn[nH]c4c3)cn3ccnc23)ccc1N1CCOCC1 +O=C(O)c1ccc(N2C(=O)C3ON(c4ccccc4)C(c4ccccc4[N+](=O)[O-])C3C2=O)cc1 +CCOC(=O)c1[nH]c(Br)c(-c2ccc(OC)c(OC)c2OC)c1Br +CN1CCN(C(CN2CCN(CCCCc3cccc4ccccc34)CC2)c2ccccc2)CC1 +Cc1cn(-c2ccc3n(c2=O)CCN(Cc2cn(C)c4c(F)cc(C(F)(F)F)cc24)C3=O)cn1 +CCCCN(CC(C)(O)c1ccccc1)S(=O)(=O)c1ccc(O)cc1 +COc1cc(C2C(C#N)=C(N)Oc3cc(N(C)C)ccc32)cc2c1OCO2 +CCCCCC(Cc1ccc(C(=O)NCCC(=O)O)cc1)C(=O)c1cc2cc(OC)ccc2n1-c1cccc(C(F)(F)F)c1 +Nc1nccc2ccc(C(=O)NC(C(=O)N3CCN(c4ccncc4)CC3)c3ccccc3)cc12 +COCCOCCOCCOCCOCCOCCOCCOCCOCc1cn(CCCCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)nn1 +COc1ccccc1CN(C(=O)CF)c1ccccc1OC1CCCC1 +COc1cc(OCc2csc(-c3ccc(C(=O)N(C)C)cc3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +Cc1nc(C(F)(F)F)c(C=CC=CC(=O)C=Cc2nccn2C(C)C)s1 +c1cncc(CNc2ccn3ncc(-c4ccc5ccccc5c4)c3n2)c1 +Cn1nc(-c2ccccn2)cc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +CC(C)CC(N)c1ccccc1N1CCN(C(=O)C(C)Cc2ccc(Cl)cc2)CC1 +O=C(O)CCCCc1cc2cc(C(=O)NC3CCCc4cc(F)ccc43)ccc2c(=O)n1-c1ccc(F)cc1 +CC(=O)Nc1cccc(-c2cc(C(C)Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)c1 +CC(C)(C)C(=O)Oc1ccc2nc(S(N)(=O)=O)sc2c1N +CC(=O)NC(C)c1ccc(CN2CCc3cc(OC(C)C)ccc3C2)cc1 +BrC(COc1cccc2c[n+](Cc3ccccc3)ccc12)CN(Cc1ccccc1)Cc1ccccc1 +CCC(CO)Nc1nc(NCc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1 +CCN(CC)c1ccc(NC(=O)c2c(-c3c(Cl)cccc3Cl)noc2C(C)C)cc1 +CCC1C(C)CC2C(=O)OC(C)C2C1C=Cc1ccc(-c2cccc(C#N)c2)cn1 +CCCC1(CC(=O)O)OCCc2c1[nH]c1c(C)c(OC(C)C)cc(C#N)c21 +Nc1ncc(-c2ccc(C3(c4noc(-c5cncnc5)n4)CCC3)cn2)cn1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1c(F)cccc1F +CCCCc1nn(Cc2cccc(C)c2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(O)COc1ccc(Cl)cc1C#Cc1ccccc1C(F)(F)F +Cc1cccc(C)c1-c1noc(C)c1NC(=O)NCc1c(F)cccc1Cl +Cc1ccccc1CSc1nc(NC(CO)CC(C)C)c2sc(N)nc2n1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(N3CCN(C)CC3)cc2)c1 +Cn1c(SCCCN2CCOC(c3ccc(C(F)(F)F)cc3)C2)nnc1-c1cncc(C(N)=O)c1 +O=C(O)c1nccc(-c2ccc(OCCN3CCOCC3)c(Cl)c2)n1 +O=C(c1ccc(-c2nc(Cc3cccs3)no2)s1)C(F)(F)F +O=C(C1CCc2c(sc3ncnc(Nc4ccc5[nH]c(=O)sc5c4)c23)C1)N1CCN(CC2CC2)CC1 +CN(Cc1ccnn1C)C(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C +CCOc1ccc(Cc2nc3cc(NC(=N)c4cccs4)ccc3n2CCN(CC)CC)cc1 +COc1cccc(C2=CCN(C(=O)C3NCC4(CC4)CC3C(=O)NO)CC2)c1 +CCc1cc(Nc2nccc3nc(-c4c(Cl)cc(C(N)=O)cc4Cl)sc23)ncn1 +CN1CCN(c2nccc3cc4c(cc23)N(C(=O)c2ccccc2Cl)CC4)CC1 +O=C(O)C(=O)CC(=O)c1cccc(Cc2ccccc2Cl)c1 +Cc1ccc(Nc2ccc3c(c2)C(=CNc2ccc(CN4CCCCC4)cc2)C(=O)NC3=O)cc1 +c1ccc(-c2nc(-c3ccco3)[nH]c2-c2ccccc2)cc1 +CCOC(=O)C1CCCN1c1c(C(=O)NCc2ccc(F)cc2F)c(=O)n(O)c2ncccc12 +CCCCCCCCCCCCCC(CC(=O)NO)C(=O)NC(C(=O)NC)C(C)(C)C +CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5cc(Cl)c(F)cc5[nH]4)no3)nc2n(CCC)c1=O +CCCc1sc(-c2ccc(F)c(OCCO)c2)nc1CSc1nc(N)cc(N)n1 +CC(NC(=O)c1cncs1)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 +C#CCNC(=O)C(C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(C)c12 +O=C(Nc1cccc2c(=O)cc(-c3nnn[nH]3)oc12)c1ccc(OCCCCc2ccccc2)cc1 +c1ccc(CN2CCCC(n3nnc4cnc5[nH]ccc5c43)C2)cc1 +O=C(C=Cc1cccn(Cc2cccc(Br)c2)c1=O)NO +c1ccc(CCCN2C3CCC2CC(CCOC(c2ccccc2)c2ccccc2)C3)cc1 +O=C(NCCCCn1cnc([N+](=O)[O-])n1)c1ccc(OC(F)(F)F)cc1 +CCOC(=O)C(C)(C)NC(=O)C(O)C(N)CC1CCCCC1 +Cc1cc(Cc2ccc(C(=O)NC3(CC(=O)NO)CCOCC3)cc2)c2ccccc2n1 +COc1ccc(C(=O)C=Cc2cccnc2)c(OC)c1OC +COc1[nH]cc(C(=O)c2ccc(-c3ccccc3)cc2)c(=O)c1OC +O=C(NCCCO)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O +COc1cc(Nc2nccc(N3CCCC(C(=O)NCc4ccc(C)cc4)C3)n2)cc(OC)c1 +CSc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(F)(F)F)nn12 +COCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ccnc(N(C)CC(F)F)n4)C3)cc2)s1 +O=C(c1ccccc1-c1ccco1)N1CCC2CN(c3cnc4ccccc4n3)C2C1 +CNc1nnc(-c2ccc3[nH]cc(-c4cccc(OC5CCC5)n4)c3c2)s1 +Cc1c(C(=O)NC2CCCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +COCCN(c1sc2ccccc2c1C)S(=O)(=O)c1ccccc1 +Cc1noc(NS(=O)(=O)c2ccccc2C(F)(F)F)c1C +COc1cccc(NC(=O)c2ccc(S(=O)(=O)N3CC(C)CC(C)C3)c(F)c2)c1 +COC1OC(C(=O)O)C(SC2OC(C(=O)O)C(OC3OC(C(=O)O)C(O)C(O)C3O)C(O)C2O)C(O)C1O +CCCn1c(SCc2cc([N+](=O)[O-])ccc2OC)nc2cc(NC(=O)NC(C)(C)C)cc(C(=O)O)c21 +COC(C)(c1ccc(F)cc1)c1ccc(C(=O)NCCCCCCC(=O)NO)cc1 +COC1Oc2c(Cl)cc(Cl)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O +COc1cc2nc(-c3ccc(N4CCOCC4)cc3)cc(O)c2cc1-c1cnco1 +OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cn[nH]c1 +O=C(O)CCCC1c2ccccc2CC1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1 +CNc1cc2c(N(C)C3Cc4ccccc4C3)ncnc2cn1 +O=C(NCCCO)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +c1cc(OC2CCNC2)c2nc(-c3nnc4ccccn34)ccc2c1 +O=[N+]([O-])c1ccc(Nc2nccc(-c3ccc(Cl)c(Cl)c3)n2)cc1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(NC3CCC(CO)C3)c2c1=O +CC(NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(Cl)cc2C(=O)c2ccc(Cl)cc2)cc1 +COc1cc(NC(C)(C)C(=O)Nc2nc3ccc4[nH]ncc4c3s2)ccc1Cl +Cc1cn(C2CC(O)C(C#N)(CO)S2)c(=O)[nH]c1=O +CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3C3Cc4ccccc4O3)cc2)cc1 +CN(c1cc2cc(c1)C(=O)NC(C(O)CNCc1cccc(C(C)(C)C)c1)COCC=CCCNC2=O)S(C)(=O)=O +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)NC3(C(=O)N4CCOCC4)CCCC3)cc12 +Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3cncn3)c1)=N2 +COc1ccc(-c2c(C(=O)O)c(=O)n(Cc3ccccc3C)c3c2oc2ccccc23)cc1 +CC(C)(C)c1ccc(C(=CC(=O)Nc2ccc3c(c2)OCCO3)c2cccc(N)c2)cc1 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+NS(=O)(=O)c1ccc(-c2nn3cc(-c4ccc(Cl)cc4)nc3s2)cc1 +CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3)nc2n(CCCOC)c1=O +O=c1oc2cc(Cc3ccccc3)ccc2n1CCN1CCOCC1 +Cc1c(OCC(F)(F)F)ccnc1COc1cccc(Nc2ncnc3cc4oc(=O)n(CCCN5CCOCC5)c4cc23)c1 +CCCCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1 +Cn1c(=O)c2c(nc(Cc3ccco3)n2C)n(Cc2ccco2)c1=O +CCCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NC(=O)c2ccc3ncccc3c2)C(C)C)nn1 +Cc1ccc(-c2ncc(CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C)cn1 +COc1cccc2sc(N3CCN(C(=O)c4ccc([N+](=O)[O-])o4)CC3)nc12 +CCC(CC)(Cc1nc2ccc(OCc3ccc(C)cn3)cc2n1Cc1ccc(OC(F)(F)F)cc1)C(=O)O +Cc1nc(C(CC2CC2)NC(=O)c2cnc(C3CC3)c(OCC3CC3)n2)no1 +NCC(=O)N1CCn2c(nc(-c3ccc(F)cc3)c2Nc2ccc(F)cc2)C1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(nc(C(F)(F)F)c2-c2ccccc2)C1 +COc1ccc(F)c(-c2ccc3c(c2)C2(COC(N)=N2)C2(COC2)C2(CCC2)O3)c1 +CC1CNc2c(cccc2S(=O)(=O)NC(CCCNC(N)N)C(=O)N2CCC(C)CC2C(=O)O)C1 +NC(=O)c1nn(CC(=O)N2C(C(=O)NCC3CC3(Cl)Cl)CC3CC32)c2ccc(OCc3ncccn3)cc12 +CC(=C1SC(=N)NC1=O)c1ccc(-c2ccc(S(N)(=O)=O)cc2)o1 +COc1ccc(-n2ccc3c(sc4ncnc(NC5CC5)c43)c2=O)cc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCC(C(=O)NCc3ccc(C#N)cc3)CC2)c2cccc(Cl)c2)CC1 +COc1cc2ncc(C#N)c(Nc3ccc(C)c(Br)c3)c2cc1OC +COc1cccc(-n2c(=O)n(Cc3c(F)cccc3F)c3cnc(NCC4CC4)nc32)c1 +O=C(C=Cc1ccc(O)cc1)CC1OC(CO)C(O)C(O)C1O +Cc1cc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4cccc(C(F)F)c4)cc32)ccc1C(=O)NC1CC1 +CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)CC1 +Cn1c(=O)n(-c2ccc(C#N)cc2)c2c3cc(-c4ccc(N)nc4)ccc3ncc21 +CC1CCCN1C(=O)c1cc(C(=O)NCc2ccc(F)cc2Cl)c2n1CCOC2 +C[N+](C)(C)CC1CC(c2ccccc2)(c2ccccc2)C(=O)O1 +CC(C)C(NC(=O)OCc1ccccn1)C(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1 +CC(C)S(=O)(=O)Nc1ccc2[nH]c(Cc3ccc(Oc4ccccc4)cc3)nc2c1 +CC(C)NC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCCC(F)(F)F)c2C1 +O=C1NCc2cc(-c3n[nH]cc3CN3CCN(c4ccc(C(F)(F)F)cn4)CC3CO)ccc2O1 +COc1c(C)c2c(c(O)c1CCOP(=O)(O)CP(=O)(O)O)C(=O)OC2 +Cc1nc(NC(C)c2cccc(-c3cncnc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CC(C)c1sc(C2CCCC2)c(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +C=CCNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 +Cc1cnc(Nc2nc(-c3ccccc3)nc3ccccc23)s1 +CN(C)c1ccc(OS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +Cn1c(-c2cn(-c3cccc(C(=O)NCCCO)c3)nn2)nc(-c2ccc(F)cc2)c1-c1ccncc1 +O=C(CCCN1CCN(c2ccc(F)cc2)CC1)NC1c2ccccc2C=Cc2ccccc21 +O=C1c2cc3c(cc2CN1CCC1CCN(Cc2ccc(F)cc2)CC1)OCO3 +CCCC(=O)N1CCCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)C1 +C=C(Br)C(=O)Nc1cccc(C=CC(=O)Nc2ccc(OC)cc2)c1 +CC1CCN(CCCCCC(=O)Nc2cc(CO)cc(Nc3ccnc4cc(Cl)ccc34)c2)CC1 +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccsc2)sc2cc(O)ccc12 +COCCOc1ccc2c(c1)C1(N=C(N)N(CC(F)(F)F)C1=O)C1(CCC(OC)CC1)C2 +O=C(Nc1cccc(NC(=O)c2cccc(N3CCOCC3)c2)c1)c1cccc(OC2CCN(CC3CC3)CC2)c1 +CCC(=O)c1ccccc1OCC(O)CN1CCC(O)(c2ccccc2)CC1 +COc1ccc(Cn2cc(CCc3cc(OC)c(OC)c(OC)c3)c3c(C)nc(N)nc32)cc1 +Cc1ccc(N2CCC(CO)C2)nc1C(=O)Nc1c(C)cc(C(=O)O)cc1C +C=Cc1cccc(C(=O)c2c(CC)c(C)nc(O)c2N(C)C)c1 +CC(=O)Nc1ccc2c(c1)-c1ccccc1S2(=O)=O +Cc1cccc2c(=O)n(CCc3ccccc3)c(-c3ccccc3O)nc12 +COC(=O)C(C)NP(=O)(OCC1C=CC(Cn2cc(C)c(=O)[nH]c2=O)O1)Oc1ccc(F)cc1 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)C2CCOCC2)C1C +Cc1nc(C#Cc2cnc(-c3cccc(C)c3C)nc2)cs1 +Cc1nnc(SCC(=O)Nc2ccccc2Br)n1-c1ccc(Cl)c2ccccc12 +CCN(CC(=O)NC(CC(=O)O)C(=O)NCCC1CCCCC1)C(=O)CCCC1CCNCC1 +Cn1ccc2ccc3c4[nH]c5cccc(F)c5c4c4c(c3c21)C(=O)NC4=O +CCOC(O)=C1C(COCCN)=NC(C)=C(C(=O)OC)C1c1cccc(-n2ccnc2)c1 +Cc1ccccc1C(=NOCCN1CCC=C(C(=O)O)C1)c1ccccc1C +COc1cc(C(=O)c2cc3c(OC)cccc3o2)cc(OC)c1OC +COc1cc(N2CCN(C3CCN(c4ccc(F)c5c(OC)cc(C(F)(F)F)nc45)CC3)CC2)c2ncccc2c1 +CCOc1nc2nn(C)cc2c2nc(-c3ccco3)nn12 +CC(CCC(=O)NNc1ccc(S(N)(=O)=O)cc1)C1CCC2C3C(=O)CC4CC(=O)CCC4(C)C3CC(=O)C12C +CC(OP(N)(=O)N(CCCl)CCCl)c1ccc([N+](=O)[O-])cc1 +Cc1cc(-c2ccc(C(=N)N)cc2)cn2cc(-c3ccc(C(=N)N)cc3)nc12 +O=C(O)C1=CCCN(CCOC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1 +Cc1c(Nc2c(C#N)cncc2C=CCCN2CCCCC2)ccc2[nH]ccc12 +CCOc1ccc(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1OCC +N#Cc1ccc(C(c2cccnc2)N2CCC(NC(=O)c3ccc(C(F)(F)F)cc3F)CC2)cc1 +O=[N+]([O-])c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 +CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(C)=O)cc1 +Cc1cc(NC(=O)Nc2ccc(N(C)C)cc2)c2cc(F)cc(F)c2n1 +CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OC)c(Br)c1 +CC1COCCN1c1cc(C2(S(=O)(=O)CCCO)CC2)nc(-c2ccc(NC(=S)NCCO)cc2)n1 +COc1ccc(C=C2SC(=Nc3ccccc3)NC2=O)cc1 +COc1cc(N2CCC(c3nc(C(=O)Nc4nc5cc(C(=O)c6ccccc6)ccc5[nH]4)cs3)CC2)nc(OC)n1 +Cc1cc(CC(C(=O)O)c2cn(CCCC(C)C)cn2)cnc1N +Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)C(N)Cc3ccc(O)cc3)O2)c(=O)[nH]c1=O +Cc1[nH]nc2c1C(c1cc(-c3cccc(CCC(=O)O)c3)cc(C(F)(F)F)c1)(C(C)C)C(C#N)=C(N)O2 +CC(=N)C(C#N)=C(O)CSc1nnnn1-c1ccc(C)cc1 +COC(=O)C1CC(OC)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +CCCCN(C)Cc1ccc2c(NC(=O)c3ccc(C)s3)c(C(=O)OC)sc2n1 +Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3cccnc3C(=O)N(C)C)cc2)s1 +CCc1ncnc(-c2ccc(C(=O)N(C)CC3CCCN(C)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +Cc1noc(C)c1CC(=O)NCc1ccc(Cl)c(C(F)(F)F)c1 +CCCCCCCCCN1NN=C(NC(=O)Nc2c(C(C)C)cccc2C(C)C)N1 +CC(C)(CO)NCc1cccnc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CCN)CC1 +COc1ccc(-n2ccc(C(=O)c3cc(OC)c(OC)c(OC)c3)c2)cc1OC(C)C +COC(=O)c1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +CCc1ccc(-c2ccc(NC(=O)Oc3ccccc3F)cc2)cc1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4cccc(C)c4)oc3C)ccc21 +O=C(NC1CC2CCC(C1)N2Cc1ccccc1)c1ccc2ccccc2c1 +CCC(NC(=O)c1cc(C(=O)NC(C)c2ccc(F)cc2)c2n1CCOC2)c1ccccc1 +Cn1cc(C(=O)Nc2cc(F)c(CC(=O)N3CC(O)CC3COC3CCC(C(=O)O)CC3)cc2Cl)c2ccccc21 +Cc1cccc(Nc2nccc(-c3ccc(Br)cc3)n2)c1 +ON=C1CCC(C2CCCC2)=C1c1ccc2c(c1)OCO2 +CC(C)(C)CC(=O)OCC1(CO)CC(=Cc2ccc(Cl)cc2)C(=O)O1 +COCCCn1c(NC(=O)c2ccc(C#N)cc2)nc2cc(CN3CCOCC3)ccc21 +N#CC1CCCN1C(=O)CNC1CC2CN(C(=O)N3CCCCC3)CC2C1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N4C(C)COCC4C)n3)C2)cc1 +CC(=O)Oc1cccc2c1C(=O)c1c(-c3ccc(F)cc3)noc1C2=O +NC(=O)c1ccc(Oc2ccc(CCNCc3cccc(Cl)c3)cc2Cl)nc1 +CC(C)CN(CC(=O)NO)S(=O)(=O)c1ccc(OCC2CCCCC2)cc1 +CNC(=O)NC1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c(F)cc(-c3ccccn3)cc12 +COCCCCN1CCN(C(=O)c2cc3c(cc2C)[nH]c(=O)c2cnn(C4CCC4)c23)CC1 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+CCc1cc2c(cc1N1CCN(CC3(O)CCOCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +O=C(O)CC(CC1CCN(C(=O)CCCc2ccc3c(n2)NCCC3)CC1)c1ccc2c(c1)OCO2 +COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(SC)cc4)sc3n2)cc1 +CC(C)C(=O)N1CCC(Nc2ncccc2-c2cnc3[nH]ccc3n2)C1 +O=C1c2nnc(-c3ccc(F)cc3)n2CCN1Cc1cccc(C(F)(F)F)c1Cl +Cc1cc(C(F)(F)F)cc(-n2ncc(-c3ccc4cc(CCN5CCCC5C)ccc4n3)c2C)n1 +CCCc1cc(=O)[nH]c(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1 +Nc1nc2c3ccc(NCCN4CCCC4)cc3nc(Cc3ccc4c(c3)OCO4)n2n1 +COc1ccc(NC(=O)Nc2cc3ccc(OC4CCN(C)CC4)c(C)c3oc2=O)cc1-c1ccccc1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccc(Cl)cc2)cc1 +COc1cc2c(=O)n(CCc3ccc(S(N)(=O)=O)cc3)c(S)nc2c(OC)c1OC +NCCCCCOCC1OC(OCCc2c[nH]c3ccccc23)C(OCc2ccccc2)C(OCc2ccccc2)C1OCc1ccncc1 +COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(F)c(OC(F)(F)F)c4)cc3)c(=O)c2cc1Cl +CCCN(CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)CCC +CCC1=CC2Cc3nc4cc(F)cc(F)c4c(N)c3C(C1)C2 +COc1ccc(OCC2CCC3CN(c4ncccn4)CCN3C2)cc1 +CC1Cn2c(nnc2-c2cnn(C)c2)C(=O)N1Cc1cccc(C(F)(F)F)c1Cl +CC(Cc1ccc(C#Cc2cnc(OC3CCC3)nc2)cc1)NC(=O)C1CC1 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+Nc1ccc(S(=O)(=O)NCCOc2ccc3c(c2)C(C2(c4ccc(Cl)cc4)CCC2)NCC3)cc1 +CCOc1nc(NC(=O)Cc2cc(OC)c(Br)cc2OC)cc(N)c1C#N +CCOC(=O)Cn1cc(-c2cnc(NC(=O)C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)nn1 +COc1ccc(-c2cncc(-c3cc4c5c(c3)CCN5C(=O)CC4)c2)cc1 +O=C(O)c1cc(-c2ccc(Br)cc2)nc2ccccc12 +Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl +CC(=O)Nc1cc(NC(C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)c2ccccc2)ccc1Cl +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3cnc(-c4ccccc4)[nH]3)CC2)C(c2ccccc2)C1 +COc1cccc(CNc2n[nH]c(-c3cccnc3Nc3cc(OC)cc(OC)c3)n2)c1 +COC(=O)CNc1nc(NCC(=O)OC)nc(NCc2ccc(S(N)(=O)=O)cc2)n1 +Cc1csc(NC(=O)NC23CC4CC(CC(C4)C2)C3)n1 +CNc1nc(Cc2ccccc2)nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)n1 +CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)o1 +O=C(c1ccco1)N1CCN(c2cnn(CCCCN3CCN(c4ccccc4Cl)CC3)c(=O)c2Cl)CC1 +CC(C)c1cccc(NC(=O)Nc2cccc(-c3cccc4[nH]nc(N)c34)c2)c1 +O=[N+]([O-])c1ccc(SC(=S)N2CCN(Cc3ccc(Br)cc3)CC2)c([N+](=O)[O-])c1 +COc1ccc(Nc2c(C(N)=O)cnc3cc(-c4ccncc4)ccc23)cc1F +COCCOc1cccc2c(NCc3ccccc3)nc(-n3c(C)nc4ccccc43)nc12 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCC(=O)N3CCC3)no2)cc1C#N +O=C(NCCC(F)CN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2ccccc2s1 +CC(C)Nc1cc(-c2c(-c3ccc(F)cc3)nn3cc(C(N)=O)ccc23)ccn1 +COc1ccc(-c2nnnn2-c2cc(Br)c(OC)c(Br)c2)cc1O +Cc1ccsc1C(=O)n1nc(Nc2ccc(S(N)(=O)=O)cc2)nc1N +N#CC(=Cc1ccc(O)c(O)c1)C(=O)OCCc1cccs1 +O=C(CCc1ccc(-c2ccc[nH]2)cc1)Nc1ccccc1C(=O)O +CC(C)(C)c1ccc(-c2noc(CCC(=O)NC3CCCC3)n2)cc1 +COc1ccc2nc(C(C)Cc3cc4c(cc3Cl)OCO4)[nH]c2c1 +Cc1cc(CNC(=O)NCC23CC4CC(CC(C4)C2)C3)on1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(NCCO)nc1OCCOc1ncc(Br)cn1 +COc1ccc2c(c1)NC(=O)Cc1cnc(Nc3ccc(OC)c(O)c3)nc1-2 +CCOC(=O)c1nn2c(=O)[nH]c3ccccc3c2c1C(=O)OCC +NS(=O)(=O)c1ccc(N2C(=O)c3cccnc3C2=O)cc1 +CN(C)CCCON=C1c2ccccc2-c2nc3c(C(=O)NCCN(C)C)cccc3nc21 +COc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)C(C)C3)c2cc1OC +OC1(C(F)(F)C(F)(F)F)CCCc2c1[nH]c1cc(Cl)c(Cl)cc21 +CC1(C)CN(Cc2ccc(F)cc2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O +Cc1ccc(C(=O)C=Cc2ccc(C(=O)O)cc2)o1 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+COc1ccc(C=NNc2ccnc3c(OC)cccc23)cc1 +Cc1cccc2c(C(=O)C(C)(C)CSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12 +O=C(NO)C(CCCc1ccccc1)CS(=O)(=O)c1ccc(Cc2ccccc2)cc1 +CCOC(=O)C1C2CCC(CC1c1ccc(-c3cccn3CC)cc1)N2 +CN=C(Cc1c(Cl)cccc1Cl)NC(=O)Nc1ccc(C#N)cc1 +Cc1ccc([N+](=O)[O-])c(OC(CCN2CCC(n3c(O)nc4ccccc43)CC2)C(C)C)c1 +CSc1nc2cc(S(=O)(=O)NCc3ccc(F)cc3)ccc2n1Cc1ccccc1 +COCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ccnc(OCC5CC5)c4)C3)cc2)s1 +O=C(NCCc1ccc(Cl)c(Cl)c1)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CC(C)(O)C#Cc1ccc2c(c1)c1cc(C#CC3CC3)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 +Cc1c(CC(F)(F)F)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 +Cc1ccccc1C(Nc1ccc(Cl)cc1C(F)(F)F)C(=O)CCc1ccncc1 +COc1ccc(C(=O)OCC2(CO)CC(=CC3CCCCC3)C(=O)O2)cc1 +COc1cc2ncc3c(c2cc1-c1cc(C(F)(F)F)nn1C)n(-c1ccc(C#N)cc1F)c(=O)n3C +CN1CCc2nc(NC(=O)c3cccc(OCC(=O)Nc4ccc(C#N)cc4)c3)sc2C1 +O=C(c1ccc(C(=O)C2CC2)c(C(=O)O)c1)c1ccc(N(CC2CC2)c2ccc(Cl)cc2)cn1 +O=C1C(=O)N(c2ccccc2Br)CCN1Cc1ccc(F)cc1Cl +Cc1nn(C)c(C)c1CN(C)S(=O)(=O)c1ccc2ccccc2c1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCN(Cc2ccccc2Cl)CC1 +CC(C)(C)CCC1(C(=O)c2ccc(Cl)c(Cl)n2)CCNC1 +O=C(c1ccncn1)N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1 +N=C(N)NCCCC(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)NCc1ccccc1 +CCCC(NC(=O)C(=O)C(C)(C)C)C(=O)Nc1ncc(C(C)C)s1 +CN1C(=O)c2[nH]c(Cc3ccc(-c4ccccc4)cc3)nc2N2C1=NC1CCCC12 +CN1CC(=O)N(c2cc(Cc3nnc(O)c4ccccc34)ccc2F)C(=O)C1 +CC(C)(C)OC(=O)NC(Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1CC(F)(F)F +Nc1ccc(S(=O)(=O)Nc2cccc(-c3ccc(C4CC4NC4CCC(N)CC4)cc3)c2)cn1 +Cc1cccc(C)c1Oc1c(C(=O)N2CCNC(C)C2)c2ncccc2n1C1CCCCC1 +Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1Cl +CCOC(Cc1ccc(OCC=C(c2ccccc2)c2ccc(-c3ccccc3)cc2)cc1)C(=O)O +CN(CCCN1CCc2oc3ccccc3c2C1)CCc1ccccc1 +Cc1cc(COc2c(C)cccc2-c2csc(N3CCC4(C(=O)O)CC4C3)n2)c(C)c2c1CN(C1CCCOC1)CC2 +CC(NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(C(C)(C)C)ccc34)nc12)C(=O)N1CC(C#N)C1 +C=CC(=O)Nc1cccc(-c2c[nH]c3nccc(Cl)c23)c1 +Cc1cccc2nccc(NCCCNCCNc3ccnc4cccc(C)c34)c12 +CC1CCCCN1C(=O)c1cc(N)n2nc(-c3ccc(Br)o3)nc2c1 +CCCc1nc(C(=O)NCCCN2CCN(c3cccc(Cl)c3C)CC2)c(C)n1-c1ccccc1OC +COC1N=C(c2ccccc2F)c2cc(C#CCN3C(=O)CCc4ccccc43)ccc2-n2c(C)nnc21 +Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccccc1 +Cc1cc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)nc(C(C)(C)C)n1 +COc1ccccc1N1CCN(CCCCNC(=O)OC(C)(C)C)CC1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)c3ccc(F)c(F)c3)CC2)C1 +CCN(CC)CCCOc1ccc2c3c(nccc13)-c1ccccc1C2=O +COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O +COc1ccc2cc(CCc3c(C(=O)O)[nH]c(=O)[nH]c3=O)c(OC)cc2c1 +COc1ccc(S(=O)(=O)N2CC(N3CCCCC3)CC2C(=O)NO)cc1 +CN1Cc2c(C3=CCN(CC(=O)N4CC(O)C4)CC3(C)C)[nH]c3nccc(c23)-c2cc(F)ccc21 +NS(=O)(=O)c1ccc(NC(=O)C=Cc2ccc(Cl)cc2)cc1 +Nc1cncc(-c2c[nH]c3ccc(-c4nnc(N)s4)cc23)n1 +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc(OCCO)cc2)cc1 +CS(=O)(=O)Nc1c(Cl)ccc2c1CCCC2c1ncc[nH]1 +CC(O)CNC(=O)CNC(=O)Cc1nc2ccc(-c3ccccc3)cc2s1 +COC(=O)C1CN(CCCc2ccccc2)CCC1c1ccc(Cl)cc1 +CCCN(C)c1nc(C)nc2c(-c3c(C)cc(OC)cc3OC)c(C)nn12 +CC(=O)c1cc(C(=O)NOC(CO)CO)c(Nc2ccc(I)cc2F)n1C +O=S(=O)(c1ccc(-c2nnn[nH]2)cc1)N(CCCCC(F)(F)F)c1sc2ccccc2c1Br +Cc1ccc(S(=O)(=O)n2ccc3ccc(N4CCN5CCCC5C4)cc32)cc1 +CC1(C)SCC(C(=O)NC(Cc2ccccc2)C(=O)N2CCCC2C(N)=O)N1C(=O)C(N)Cc1ccc(O)cc1 +COC1CC(CF)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +COc1cc(C(F)F)ccc1-c1nccc2cc(S(=O)(=O)Nc3nccs3)ccc12 +CCCC(=O)NCCc1c(CN2c3ccccc3CC2C)[nH]c2ccc(OC)cc12 +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1ccc(S(=O)(=O)CCCN2CCOCC2)cc1 +CCc1cc2c(cc1CC)CC(NCC(O)c1ccc(O)c3[nH]c(=O)c(C)cc13)C2 +Clc1cccc(Cl)c1Cc1sc(NCc2ccc3c(c2)CCO3)nc1-c1ccccc1 +COc1ccc(CO)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 +CC1CN(CCC(O)C2CCCC2)CCC1(C)c1cccc(O)c1 +C=CCN(Cc1ccc(N(CC)CC)cc1)S(=O)(=O)c1ccc(C)cc1 +O=C(NO)c1cnc(NCc2ccc(-c3ccccc3)cc2)nc1 +CC(C)Nc1nc(-c2cnn(CCN3CCOCC3)c2)cc2ncn(C)c(=O)c12 +C=C1CCC2C3Cc4ccc(C(N)=O)c(O)c4C2(CCN3CC2CCC2)C1 +O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(c2ncnc3cc4ccccc4cc23)CC1 +CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cn2)cc1)C(=O)C=Cc1ccccc1 +c1ccc(-c2cccc(CN3CCN(c4cccc5c4OCCO5)CC3)c2)cc1 +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)N(C)c1ccc(Cl)cc1 +O=C(Nc1cnccn1)Nc1ccnc2ccc(C(F)(F)F)cc12 +O=C(NCCCCN1CCCC2c3ccc(O)cc3CCC21)c1ccc(-c2ccccc2)cc1 +COc1cccc(-c2cccn3nc(Nc4ccc(C5CCNCC5)cc4)nc23)c1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(-c3n[nH]c(=O)o3)c12 +CCn1c(=O)ccc2cnc(Nc3ccc(N4CCC(CCCO)CC4)cc3)nc21 +CC(C)(C)c1ccc(C(=O)NC2CCCN(c3nc(C(N)=O)c(Nc4ccccn4)s3)C2)cc1 +CC1(C)CCc2sc(NC(=S)NC(=O)c3ccccc3)c(C(=O)O)c2C1 +N=C(N)NCCNC(=O)C=CC1=C(C(=O)O)N2C(=O)C(=Cc3ccccn3)C2S(=O)(=O)C1 +CC(C)(C)C(O)C(=O)N1CCCC1C(=O)NCc1cc(Cl)ccc1CN +COc1cc(Cc2cnc(N)nc2N)ccc1OCc1ccccc1 +CC1CN(C2CC(c3ccc(F)cc3)c3ccc(Cl)cc32)C(C)CN1C +OC(c1ccccc1)(c1ccccc1)C(c1ccccc1)N1CCOCC1 +CC1CCC(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)C2CCN(S(C)(=O)=O)CC2)CC1 +O=S(=O)(c1ccccc1)N1CCC2(CC1)OOC1(OO2)C2CC3CC(C2)CC1C3 +O=C(O)c1ccc(Nc2cc(N3CCN(C4CCCCC4)CC3)c3noc4c3c2C(=O)c2ccccc2-4)cc1 +CC(C)CC(NC(=O)C(C)NC(=O)CC(O)C(COCc1ccc(Br)cc1)NC(=O)c1c(F)cc(F)cc1F)C(N)=O +Cc1cccc(OCCCn2cnc(-c3ccccc3)c2C)c1NC(=O)NCC(C)(C)C +Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3)C2)c1 +CC(=NNC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1)c1ccco1 +CS(=O)(=O)Cc1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CCOC(=O)C1=C(C)NC(=O)N(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1 +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(CC3CCCCC3)C2=O)cc1 +CC1(C2CCN(c3ncc(C(F)(F)F)cn3)CC2)Cc2cc(C3=CCN(S(C)(=O)=O)CC3)ncc2O1 +CC(=Cc1ccccc1)CC(CC(N)C(=O)O)C(=O)O +CS(=O)(=O)c1cc(Cl)c(NC(=O)N2CCN3C(=O)N(C4CC4c4ccccc4)C(=O)C3C2)c(Cl)c1 +Cc1c(C(=O)Nc2nc3ccccc3[nH]2)oc2c(Cl)cccc12 +CN(CC(=O)NC(CCCCN)C(=O)C(=O)Nc1cccc(N)c1)C(=O)c1ccccc1Sc1ccccc1C#N +COc1ccc2c3c4c(c5c(ccc6ccn(C)c65)c3n(CCCN3CCC(C(N)=O)CC3)c2c1)C(=O)NC4=O +Cc1cccc(-n2c(C=Cc3ccc([N+](=O)[O-])o3)nc3ccccc3c2=O)c1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1cccc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1Cl +CC1CN(Cc2ccccc2)CC1c1nn2c(-c3cccnc3)ncc2c(=O)[nH]1 +COc1ccc2c(c1)C(CCNC(=O)C1CCC1)CC(c1cccc(C(F)(F)F)c1)C2 +CNC(=O)c1ccc(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c(F)c1 +CON(C)C(=O)c1ccc(-c2ccc(OCC3CCN(C(=O)OC(C)C)CC3)cn2)cc1 +CC(=O)Nc1ccc(OCC(C)(O)C(=O)Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)cc1 +COc1ccc(-c2cc3ccccc3oc2=O)cc1NC(=O)c1ccc([N+](=O)[O-])o1 +CC(C)(C)C(O)C(=O)N1CCC2CC21C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +CCCCCCNC(=O)Oc1cccc(-c2ccc(C(C)C(=O)O)cc2Cl)c1 +COc1cccc(CCN2CCN(c3ccccn3)CC2)c1OCCc1ccccc1 +C[N+](C)(CCCCNC(=O)CCc1ccc(OCc2ccccc2)cc1)CCNC(=O)c1nc(Cl)c(N)nc1N +CCN(CC)CCNc1nc(Nc2ccc(C)cc2)nc(Nc2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)n1 +Cn1c(=O)c2nc(C=Cc3cccc(F)c3)[nH]c2n(C)c1=O +COc1ccccc1N1CCN(CCCCNC(=O)c2cc(-c3ccco3)[nH]n2)CC1 +CC(C)CN(NC(=O)Cc1ccc(OCCN2CCOCC2)cc1)c1nc(C#N)ncc1Cl +O=C(NCC#Cc1ccc2nccc(OCC3CCCCO3)c2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +c1cncc(CNCc2ccc(CN(CC3Cc4ccccc4CN3)C3CCCc4cccnc43)cc2)c1 +C=C(C)C1CCC(C)(O)C1CC1=C(O)C(C)(CC=C(C)C)C(=O)C(C(=O)C(C)CC)=C1O +Cc1cc(Cl)c(S(=O)(=O)N2CCCCCC2)cc1OCC(=O)NC1CCCCC1 +N#CC1CC1CN(C(CCC(F)(F)F)C(N)=O)S(=O)(=O)c1ccc(Cl)cc1 +CC(=O)N1Cc2c(n(C)c3nc(-n4ccc(OCc5ccccc5)cc4=O)ccc23)CC1C 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+Cc1ccc2c(c1)C(O)C(N1CCC(c3cccc4c3OCCO4)CC1)C2 +CC(C)C1CCN(CCOc2ccc(C3Oc4ccc(O)cc4SC3c3ccc(O)cc3)cc2)C1 +CN(CCCCC1(C)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1)c1ccccn1 +Nc1nccc(-c2[nH]c(C3CCNCC3)nc2-c2cccc(C(F)(F)F)c2)n1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(COc3ccc(F)c(C)c3)CCCC2C)c1 +CC1C2Cc3cc4ncnc(NCCc5ccc(-c6ccccc6)cc5)c4cc3C1(C)CCN2CC1CC1 +COc1cc2nc(N3CCN(c4ncccn4)CC3)nc(N)c2cc1OC +O=C(c1n[nH]c2c1CCN(CC(F)(F)F)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 +OCCN1CCN(c2cc(Nc3nccc4nc(-c5c(Cl)cccc5Cl)[nH]c34)ncn2)CC1 +CCCc1cc(=O)oc2c3c(c4c(c12)OC(C)(C)CC4)OC(C)C(C)C3O +Clc1ccccc1Cn1cc(-c2ccc3[nH]ncc3c2)nn1 +CS(=O)(=O)NCCCCCNc1nc2c(s1)CCSc1ccc(F)cc1-2 +COc1ccc(CNC(c2ccc(Cl)cc2)c2cccnc2)cc1 +O=C(C=Cc1ccc(S(=O)(=O)N2CCc3cccnc32)cc1)NO +O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1ncc(C(F)(F)F)cc1Cl +CC1CN(CCCC2C3CCCCC3CC3C(=O)OC(C)C32)C(C)CN1 +O=C(c1ccc([N+](=O)[O-])o1)N1CCN(c2nc3c(F)cc(F)cc3s2)CC1 +Cn1c(=O)[nH]c2nccc(Oc3ccc(NC(=O)Nc4cccc(SC(F)(F)F)c4)c4ccccc34)c21 +COc1ccc(O)c(C(=O)c2ccc(C=CC3CCCNCC3NC(=O)c3ccncc3)cc2)c1F +CCC(CC)(COc1cc(C)c(-c2ccc(-c3ncc(C(F)(F)F)[nH]3)c(Cl)c2)cn1)C(=O)O +O=C(NC1CCN(CC(F)(F)F)CC1)c1ccc(N2CCCCC2)nc1 +CCOc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccc3)c2c1 +O=C(Nc1ccc(OC(F)(F)F)c(F)c1)c1cnc(N2CCC(CO)C2)c(-c2cncnc2)c1 +COCc1cccc(CC(O)C=CC2C(O)CC(F)C2CCSCCCC(=O)O)c1 +Cc1cn(C2CC(N=[N+]=[N-])C(COP(=O)(Oc3cccnc3)Oc3ccc(Cl)cc3Cl)O2)c(=O)[nH]c1=O +Cc1ccc2c(c1)nc(N1CCN(Cc3ccccc3)CC1)c1cccn12 +COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccc(F)cc2)cc1 +Cc1cnc(-c2ccnc3c(C(=O)C(=O)N4CCN(C(=O)c5ccccc5)C(C)C4)c[nH]c23)s1 +COC(C)C(=O)Nc1ccc(F)c(C23COCC2S(=O)(=O)C(C)(C)C(=N)N3)c1 +Cc1ccc2cc(C(=O)NC3(C(=O)NC(CCCN4CCC(N5CCOCC5)CC4)Cc4ccccc4)CCCC3)sc2c1 +CN1c2ccccc2C(=O)N2CCc3c(n(C(=O)c4cccc(Cl)c4)c4ccccc34)C21 +CN1CC(COc2ccc(C(=O)Nc3cc(CC(=O)O)ccc3F)c(Cl)c2)Oc2ccccc21 +CCCC(=O)c1c(C)[nH]c2c1C13CC1CN(C(=O)c1cc4cc(OC)c(OC)c(OC)c4[nH]1)C3=CC2=O +NC(=O)c1c(Oc2cccc(NS(N)(=O)=O)c2)cc(F)c(F)c1Nc1ccc(I)cc1F 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+O=C(O)C(=Cc1ccc(Oc2ccccc2Br)cc1)NC(=O)c1ccc(F)c(F)c1 +CC(NC(=O)OCc1ccccc1)C(=O)Nc1ccc(C2SC(=Nc3ccc(C#N)cc3)N(Cc3ccco3)C2=O)cc1 +CC(C)Nc1nc(-c2ccc(C3(O)CCCC3)cc2)cc2ncn(C)c(=O)c12 +CC(NCCCCNc1ccnc2cc(Cl)ccc12)C12CC3CC(CC(C3)C1)C2 +CC1(C)OC(=O)N(c2ccc(C(=O)Nc3cccc4cccnc34)cc2)C1c1ccncc1 +COCCNc1cc(-n2c3c(c4ccccc42)C(=O)CCC3)ccc1C(N)=O +Cc1cc(C(Nc2ccc(F)c(CN3CC(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl +CC(=O)c1ccc(-c2ccc(-c3cc(C(=O)NCC4CCC(C(=O)O)CC4)sc3F)cc2)cc1 +COc1ccc(C(=O)Nc2cccc(C(CCN(C)C(=O)OC(C)(C)C)Nc3ncnc4c(C(N)=O)cccc34)c2)cc1 +CC(c1ccc(F)cc1)N1C(=O)OC(Cc2ccccc2)(c2nc3cc(-c4cccnc4)ccc3[nH]2)C1=O +O=C(NC1CCCC(c2nc3ccccc3[nH]2)C1)c1ccc2c(c1)OCCO2 +Cc1cc(Oc2cccc(N(Cc3cccc(OC(F)(F)C(F)F)c3)CC(O)C(F)(F)F)c2)ccc1Cl +CCOc1ccc2c(c1)CCC2Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O +CCOC(=O)c1cnn2c1n[n+]([O-])c1ccc(Cl)cc12 +CCC(=O)N1Cc2cc(OC)ccc2C(Cc2c(Cl)cncc2Cl)=N1 +CC1(C)CCc2c(C(=O)Nc3cnn(C(c4ccccc4)C4CCS(=O)(=O)C4)c3)n[nH]c2C1 +O=C(NCCN1CCC2(CC1)C(=O)NCN2c1cccc(F)c1)c1cnc2ccccc2c1 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+CC(C)C(=O)N1CCn2cc(C3=C(c4cnc5ccccn45)C(=O)NC3=O)c3cccc(c32)C1 +CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Nc2ccc(Cl)cc2)CC1 +CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O +Cc1ccc(NS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1C +CC1CN(CCCn2c3ccc(Br)cc3c3cc(Br)ccc32)CC(C)N1 +O=c1cc(-c2ccccc2)oc(O)c1C(CC1CC1)SC1CCCC1 +NS(=O)(=O)c1ccc(N2C(=O)CSC2c2cccc(Br)c2)cc1 +COC1CN(c2cc(C3CCN(C4COC4)CC3)cc(-c3cnc(N)c(C(F)(F)F)c3)n2)C1 +CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCNC(C)=O +O=C(c1nc2ccccc2[nH]1)C1CC(Oc2ncccc2C2CCOCC2)C1 +CC1(C(=O)N2CCC(c3ccccc3)CC2)CCCC2(C)c3ccccc3CCC12 +Fc1ccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)cc1F +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)N1CCCN(Cc2c(Cl)cccc2Cl)CC1 +COCCOc1nc(NS(=O)(=O)NCc2ccccc2)c(Oc2ccccc2OC)c(OCCOc2ncc(Br)cn2)n1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC23CC4(F)CC(F)(CC(F)(C4)C2)C3)cc1F +CC1OC(n2cnc3c(N)nc(OCC4CC45CC5)nc32)C(O)C1Cl +COc1ccccc1C=CC(=O)NC1CCC(CCN2CCc3ccc(OS(C)(=O)=O)cc3CC2)CC1 +CCC(NC(=O)C(CS)C(C)c1ccccc1)C(=O)O +CC(C)(O)C(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1c(F)cccc1F 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+CC1CN(C(=O)c2cn3c4c(cccc24)OCC3C2CCCCC2)CC(C)N1CCO +COc1ccc(N2CCCC2=O)cc1COc1ccc(-c2nc3cc(C(=O)O)ccc3n2C2CCCCC2)c(F)c1 +NC(=O)c1cc(N2CCNCC2C(N)=O)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +CCc1ncnc(-c2cc(F)c(C(=O)N3CCn4cnnc4C3)c(F)c2)c1C#Cc1ccc(N)nc1 +CC(C)c1ccccc1OCCN1CCC(N(CC2CC2)S(=O)(=O)c2cccc(F)c2)CC1 +CNC(=O)c1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccccc2)sc2ccccc12 +Cc1cc(C)c(-c2csc(NC(=O)c3ccc(C#N)cc3)n2)c(C)c1 +O=C(Nc1ccc(CCC2CCCCN2)cc1)c1cnc(Cl)cn1 +CCCCc1nnc(SCC2CCCCC2)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cc(C=C2CCCN3CCC(c4cc(F)c(F)c(F)c4)ON=C23)ccc1-n1cnc(C)c1 +CC1CCN(c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)CC1 +CCC(C)C(NC(=O)c1cccc(Cn2ccnc2)c1)C(=O)O +CN1Cc2c(-c3ccc(C(=O)O)cc3)[nH]c3nccc(c23)-c2cc(F)ccc21 +O=C1c2ccc(O)cc2C23CCCCC2C1N(CCF)CC3 +O=C(O)CCCOc1ccccc1-c1cc2ccc(C(=O)NC(c3ccccc3)c3ccccc3)cc2o1 +N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1c(F)c(F)c(F)c(F)c1F +O=C(Cc1c[nH]c2ccccc12)NCCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2 +CC(Nc1ccc(F)c(F)c1)c1cc(C(=O)N(C)C)cn2c(=O)cc(N3CCOCC3)nc12 +CC(=O)NC(c1cccc([N+](=O)[O-])c1)c1ccc2cccnc2c1O +CC(O)(COc1ccccc1)C(=O)N1CCc2c(C#N)cccc21 +N#Cc1nc(-c2ccnc(Nc3ccc(CN4CCOCC4)nc3)n2)ccc1N1CCC2(COC2)C1 +c1ccc(CCN2CCC3(N4CCCC4)CC(c4ccccc4)C2C(c2ccccc2)C3)cc1 +Cc1ccn(-c2ccc(C(=O)N3Cc4cccnc4Nc4ccccc43)c(C(F)(F)F)c2)n1 +CCCn1cc(-c2cn3ncc(C(N)=O)c(NC4CN(c5ncc(C#N)cn5)CC4C)c3n2)cn1 +O=S(=O)(Nc1ccccc1)c1ccc2c(c1)CCN2c1cccc(CCCC2CCCC2)c1 +CN(C)S(=O)(=O)N1CCN(c2ccc(CN(CC(F)(F)F)S(=O)(=O)Cc3ccccc3)c(F)c2)CC1 +COc1ccc2[nH]nc(C(=O)NCC3CCN(Cc4ccc(C(F)(F)F)cc4)CC3)c2c1 +CC1CN(c2ccc(NC=C3C(=O)NC(=O)c4ccc(I)cc43)cc2)CC(C)N1 +CCOc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1F +O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1NC(=O)c1scc(Cn2ccnc2)c1Cl +CCCC(=O)Nc1cccc(-c2nc(Nc3ccc4[nH]ncc4c3)c3cc(OCCOC)c(OC)cc3n2)c1 +CCCCc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNCC21 +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCCCc1ccc(S(=O)(=O)O)cc1 +NCCCCN(Cc1nc2ccccc2s1)C1CCCc2cccnc21 +Nc1ncc(-c2cc(C3C4CN(C5COC5)CC43)n(C3CCC3)n2)cc1OC(F)(F)F +CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(=O)C3CC3)cc12 +CC(O)(CS(=O)(=O)c1ccc(NC(=O)CCl)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +COC1CCC2(CC1)Cc1ccc(-c3ccc4[nH]cc(C)c4c3)cc1C21N=C(C)C(N)=N1 +CNc1ccc(C=Cc2cccc(C=Cc3ccc(NC)c(O)c3)n2)cc1O +N#Cc1c(-c2ccc(C(F)(F)F)cc2)cc(NCCN2CCCCC2)n2c1nc1ccccc12 +CNC(=O)c1ccccc1Nc1nc(Nc2ccc(CN)cc2)n2ccnc2n1 +CCNC(=S)Nc1cc(-n2cnc(CN3CCCC3)c2)ncn1 +COc1ccc(NC(=O)N2CCN(c3ccc(C)cc3C)CC2)cc1N1CCN(C)CC1 +COc1ccc(N2CCOCC2)cc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +COc1cc(C=Cc2nc3n(n2)CCCC3c2ccc(C(F)(F)F)cc2)ccc1-n1cnc(C)c1 +Cc1c[nH]c2c(Nc3nc(NC4CCCCC4N)cc4cc[nH]c(=O)c34)cccc12 +CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1 +NS(=O)(=O)c1ccc(NC(=O)C=Cc2ccccc2OC(F)F)cc1 +CCN(CC)C(=O)c1ccc(-c2c3ccc(=[N+](C)C)cc-3[se]c3cc4c(cc23)C(C)(C)CCN4C)s1 +COCCOc1ccc(-c2c(C)nc3c(N4CCOCC4)nccn23)cn1 +CN(CCCCCCCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1 +Cc1ccccc1-n1ncc(-c2nc(-c3cc(F)ccc3F)no2)c1-c1ccccc1 +O=C(O)C1Nc2cc(Cl)cc(Cl)c2S(=O)(=O)N1Cc1ccccc1 +CCCCc1nc2c(C)ccnc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C1c2ccccc2C2C(C(=O)O)C(C(=O)O)C2c2ccc(-c3ccc(Cl)cc3)cc21 +Clc1cccc(-c2cnc3ccc(N4CCC(N5CCCCC5)CC4)nn23)c1 +O=[N+]([O-])c1cccc2c1CN(c1ncnc3c1ncn3C1OC(CO)C(O)C1O)CC2 +CCCC1(C)SC(NC2C(C)(C)C2(C)C)=NC1=O +CNC(=O)c1sc2ncnc(N3CCC(COCCN4CCCC4)CC3)c2c1-c1ccccc1 +O=c1[nH]nc2c3c([nH]c4cccc1c43)CNC2 +Cc1ccc(C(=O)NC2CC2)cc1-c1ccn2c(C3CCOCC3)nnc2c1 +Oc1ccc(-c2cc(-c3ccccc3Cl)nc3c2oc2ccccc23)cc1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NS(=O)(=O)c1ccccc1 +N=C(N)Nc1ccc(C(=O)Nc2cccc(SC(CC(=O)O)c3cccnc3)c2)cc1 +O=C(Cn1c(=O)n(-c2ccccn2)c2ccccc21)Nc1ccc2c(c1)CC1(C2)NC(=O)NC1=O +O=C(CCN1CCCCC1CCO)Nc1ccc2c(=O)c3cc(NC(=O)CCN4CCCCC4CCO)ccc3[nH]c2c1 +CCN1CCN(Cc2ccc(C(=O)Nc3ccc(C)c(-n4cc(-c5cccnc5)cn4)c3)cc2)CC1 +CCc1n(Cc2cc3ccccc3o2)cc[n+]1CC(=O)c1ccc(OC)cc1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc(C(F)(F)F)cc4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 +CC(Sc1cc(-c2ccc(C(=O)N3CCC(N4CCCC4)CC3)c(F)c2)cnc1N)c1c(Cl)ccc(F)c1Cl +CC(C)(C#N)CCOc1cc(Cl)cc(Cl)c1-c1nc(N)nc2c1CN(C(=O)NC1CCC1)C2 +COCCOc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)c1F +Nc1nnc(-c2ccc3[nH]cc(-c4nccc(OCC(F)(F)F)n4)c3c2)o1 +COc1cc2nncc(-c3cnc(N4CCC(C(C)(C)O)CC4)c(C)c3)c2cc1OC1CC1 +CCCC(O)c1cnc(N2CCn3c(nc4cc(CO)c(S(C)(=O)=O)cc43)C2C(C)C)nc1C(F)(F)F +CC(N)C(=O)N1CCCN(CCCOc2ccc(-c3noc(C4CC4)n3)c(F)c2)CC1 +COC(=O)c1ccc2c3c(cc(N)c2c1)N(C(=O)c1cc2cc(OCCN(C)C)ccc2[nH]1)CC3CCl +CN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc(C(N)=O)c4)c3c2)CC1 +CC(=O)N(Cc1ccccc1Cl)CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(c2ccccc2)CC1 +CC(C)c1nc(C(=O)NCC2C3CN(CC(C)(C)F)CC23)c2ccccn12 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCC(O)(C(F)(F)F)CC4)ncn3)c2c1 +Cc1cccc(-c2nnc(SCC(=O)NC3CCCCC3)n2Cc2ccccc2)c1 +O=C(O)C1OC(Oc2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)C(O)C(O)C1O +CCCCCCCCC=CCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCCC(C)C)cc1 +CCCCCCCCCCOC1=C(C(=O)O)C(c2ccc3c(c2)OCO3)Oc2ccc(OC(C)C)cc21 +O=C(NCCCCc1ccc(C(F)(F)F)cc1)c1ccccc1CNCCc1ccc(O)cc1 +CN(C(=O)CNc1ccc(C(F)(F)F)cc1)C(CN1CCC(O)C1)c1ccccc1 +O=C(Nc1cccc2cccnc12)c1ccc(N2C(=O)C3C4CCC(C4)C3C2=O)cc1 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(C)cc1 +CCN(CC)C(C)(C)CNc1cc(-c2ccccc2)c(-c2ccccc2)nn1 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+O=c1cc(-c2nc3ccccc3n2C2CC3CCCC(C2)N3C2CC3CCCCC(C3)C2)[nH]c(=O)[nH]1 +Cc1cc(O)c(-c2ccc(C(C)CS(N)(=O)=O)cc2)c2c1[nH]c(=O)c1sccc12 +O=C1c2ccccc2C(=O)c2c(NCCCN(CCCl)CCCl)ccc(NCCCN(CCCl)CCCl)c21 +COC(=O)c1c(C)[nH]c(C)c1C(=O)c1ccccc1CCc1ccccc1 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccc(C#N)nc3)n2)CC1 +CC(CCCc1cccnc1)NC(=O)C=CC=C(c1cccc(F)c1)c1cccc(F)c1 +CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1cccc2ccccc12 +COC(=O)C1=C2C=CC(C)C=C2c2nc(-c3ccccc3)nn2C1 +CNC(C(=O)NC(C(=O)N(C)C(C=C(C)C(=O)O)C(C)C)C(C)(C)O)C(C)(C)c1ccccc1 +CC(Cc1cccc(CNCCc2c(Cl)cccc2Cl)c1)NCC(O)c1ccc(O)c2[nH]c(=O)sc12 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)C(=O)NC(CO)Cc1ccccc1 +COc1nc2[nH]c(=O)[nH]c2nc1NS(=O)(=O)c1cccc(Cl)c1Cl +O=C(Nc1ccc(F)cc1F)Nc1cnc2ccc(Cl)cc2c1-c1ccccc1 +CCCCC(N)C(=O)Nc1cc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OCc2ccccc2)ccc1N +O=C(Nc1cccnc1)C(=O)c1cc(Cc2ccc(Cl)cc2)n2ccccc12 +CSc1ccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CCN(C)CCc3ccccn3)c2=O)cc1 +N#Cc1ccc(-c2cn(-c3ccc(C(=O)O)cc3)cc2C#N)cc1 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+COc1ccc(COc2ccc(C(CC(=O)O)c3ccc(F)cc3)cc2)cc1 +C(=Cc1ccccc1)CN1CCC(c2ccc(Oc3ccccc3)cc2)CC1 +COc1ccc(OC)c(CCOc2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2C(F)(F)F)c1 +N#Cc1cccc(-c2ccc(N(C(=O)Nc3cc(Cl)cc(Cl)c3)C3CCN(C4CCCC4)CC3)cc2)c1 +CCOc1cc(C#N)cc(-c2ccc3ccc(C)nc3c2)c1 +O=C(NCC1CNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 +Cc1ccccc1C=CC(=O)c1ccc([N+](=O)[O-])o1 +Cc1cc(Cl)ccc1C1c2c(nn(CC3CCCN3C(=O)N(C)C)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C +Cc1cc2c(cc1C(C)c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C +COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3ccc(C(=O)O)cc3)nc2C=CC(=O)O)cc1 +COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1c(F)c(C)nn1C)C2=O +COc1cccc(OC)c1C1CC(F)C(=O)N1Cc1ccc2oc3ccccc3c2c1 +O=C(Nc1cc[nH]c(=O)c1)c1ccc(Cl)cc1Oc1ccc(F)cc1 +COc1ccc(-c2n[nH]c3ccc(-c4n[nH]c(CN(C)C)n4)cc23)cc1 +CCN(CCCNC1=CC(=O)C(NCCCCCCNC(=O)CCCCC2CCSS2)=CC1=O)Cc1ccccc1OC +COc1ccc2c(c1)C13CCCCC1C(C2)N(C)CC3 +O=C(NCc1ccccc1)c1cccc(NCc2[nH]nc(-c3ccncc3)c2-c2ccccc2)c1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(-n3cccn3)c2)CCCOC1 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+O=C1CC(CN2CCC(C(=O)c3ccc(F)cc3)CC2)Cc2nc(N3CCCC3)sc21 +COc1cnc(OCCOc2ncnc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2-c2ccc(C)cc2)nc1 +Cc1c(C)c2c(c(Cn3cc(-c4ccc(O)c(O)c4)nn3)c1O)CCC(C)(C)O2 +COc1ccc(-c2nc(N)sc2-c2cc(OC)c(OC)c(OC)c2)cc1 +COCCN1CCN(Cc2ccc3oc4cccc5c(=O)[nH]nc(c3c2)c45)CC1 +c1ccc(-c2csc3[nH]nc(N4C5CCC4CC(COCCN4CCCC4)C5)c23)cc1 +N#Cc1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)C2)c1 +O=C(Nc1cccc2c1CC(O)C2)NC1CCC(c2ccccc2F)C1 +CN(C)C(=O)c1sc2ncnc(N3C4CCC3CC(NC3CCC3)C4)c2c1-c1ccccc1 +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NCC(c1ccc(F)cc1Cl)N1CCC(N2CCCCC2)CC1 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3cccc(OC)c3)cc2)C1CO +COc1cccc(C(c2c(C)[nH]n(-c3ccccc3)c2=O)c2c(C)[nH]n(-c3ccccc3)c2=O)c1OC +N#Cc1ccc(-n2cc(C(=O)Nc3ccc(C4CNCCO4)cc3F)cn2)c(F)c1 +Cc1cc(Cl)ccc1N1CCN(C(=O)N2CCOCC2)CC1 +COC(=O)C=C(C)c1ccc(C(=O)N=c2[nH]c3cc(N(C)C(=O)c4ccccc4)ccc3n2CCC(N)=O)s1 +CC(C=O)Cc1cc(C(=O)c2ccccc2)ccc1OC(=O)C(C)(C)C +CCCC1(CC(=O)O)OCCc2c1[nH]c1c(C)c(OCCc3ccncc3)cc(C#N)c21 +CC1CN(c2cc(Nc3cc(C(C)C)[nH]n3)nc(NCc3cc(C(C)C)no3)n2)CCN1 +CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cccc(F)c5)cc34)c(NC3CCOCC3)c2)CC1 +C=C(C)C1CCC2(C(N)=O)CCC3(C)C(CCC4C5(C)CCC(=O)C(C)(C)C5CCC43C)C12 +CC1(C)OC(=O)N(C2CCC(n3c(=O)[nH]c4cc(C#N)cnc43)CC2)C1c1ccccc1 +CCOC(=O)Nc1nc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(C#N)cc2)n1 +COc1cccc(NC(=O)Cc2ccc(Nc3ncnc4cc(OC)c(OC)cc34)cc2)c1 +CCOC(=O)CCCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +CC1OCCC1N(NC(=O)OC(C)(C)C)c1nc(C#N)ncc1Br +Cc1cc(C)n(-c2nc(NCC(F)(F)F)cc(-n3cccn3)n2)n1 +Cc1ccccc1NC(=O)CSc1nnc(-c2ccccc2)[nH]1 +CCOC(=O)C(C)Sc1nc2cc(-n3nc(C)n(C(F)F)c3=O)c(F)cc2s1 +Cn1ncc(Cl)c1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCCC1 +O=C(CC(CS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)NC1CCCc2cc(CN3CCCCC3)ccc21 +CC1CN(Cc2c[nH]nc2-c2c[nH]c(C(N)=O)c2)CCN1c1ccc(C(F)(F)F)cn1 +CC(C)C(N)C(=O)SCCOP(=O)(COCCn1cnc2c(N)ncnc21)OCCSC(=O)C(N)C(C)C +Nc1c(C(=O)c2ccccc2)cc[n+]([O-])c1-c1ccccc1 +CC1CCC(COc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2F)CC1 +NC1(C(=O)N2CCCC2c2ccccc2)CCN(c2ncnc3[nH]ccc23)CC1 +CN(C)CCOc1ccc(-c2oc3ncnc(NCC4CCCO4)c3c2-c2ccccc2)cc1 +CC12CN(c3ncccn3)CC(C)(O1)C1C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C12 +CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1 +CCCOc1ccnc2[nH]cc(-c3ccnc(N)n3)c12 +O=C(Cn1nc(C(F)(F)F)c2c1CCCC2)Nc1sc2c(c1CO)CCCC2 +COc1cc2c(c(OC)c1OC)-c1ccc(=O)c(OC)cc1C(NC(=O)C(F)(F)F)CC2 +CCc1ccc(CN2CCC3(CCN(C(=O)CNC(C)=O)CC3)Oc3ccccc32)cc1 +CC(C)c1ccccc1OCCN1CCC(NC(=O)c2ccc(F)cc2)CC1 +O=c1c2ccc3c(=O)n(CCN=C=S)c(=O)c4ccc(c(=O)n1CCN=C=S)c2c34 +O=C(c1ccccc1)c1ccc2c(c1)sc(=O)n2CCN1CCCC1 +CCN(CC#N)C(=O)C1CC(C(=O)N2CCCC2)C(C)N1 +CNC(=O)Cn1cc(-c2cnc(N)c3c(-c4ccc(Oc5ccccc5)cc4)csc23)cn1 +CC(C)OCCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O +O=C(Nc1cccc(-c2cnc3c(NC(=O)c4ccc(F)c(Cl)c4)nccn23)c1)c1ccc(F)c(Cl)c1 +CC(CO)NC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 +O=C(CCCCCN1CCCCCC1)n1c2ccccc2c2ccccc21 +CC(=O)Nc1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)C(N)Cc1c[nH]cn1)C2 +Nc1ncnc2c1C(=O)N(c1ccc(-c3cccc(Cl)c3Cl)cc1)CCO2 +O=C1N(c2ccc(F)cc2)CCc2nc(COc3cccc(F)c3)cn21 +CCC1CN(c2cccc(C(F)(F)F)c2)C(=O)C1c1cccc(F)c1 +Clc1cccc(N2CCN(CCCCc3cn(-c4ccc5[nH]ccc5c4)nn3)CC2)c1Cl +CCCC(NC(=O)C(Cc1c(Br)[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)N1C(C)CCCC1C)C(=O)O +COc1ccccc1C(=O)c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12 +CC1=CC(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)=CC2C=NNC12 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)Nc3cccc(Br)c3)CCC12 +CCOC(=O)c1c(-c2cccc(C(C)=O)c2)[nH]c2cc(OC)ccc2c1=O +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(C#N)c2SC2CCCCC2)nc1 +Cc1cc2oc(=O)c(Cc3cccc4ccccc34)c(O)c2cc1C +N#Cc1ccc(Oc2ccc(S(=O)(=O)Nc3nccs3)cc2C#N)cc1Cl +O=C(CCCCc1ccc(O)cc1)NNCc1ccc(O)c(O)c1O +O=C(Nc1ccc(Cl)c(Cl)c1)Nc1ccc(Oc2ccnc(-c3ncc(C(F)(F)F)[nH]3)c2)cc1Cl +Cc1cccc(Cl)c1C(=O)N1CC2CN(CCC(NC(=O)C3CCCC3)c3ccccc3)CC2C1 +Cn1nc(-c2ccc(F)cc2)c2c1CCN(C(=O)CC(N)Cc1cc(F)ccc1F)C2 +COC(=O)C1(C)CCCC2(C)c3cc(OC)ccc3C(=O)CC12 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+O=C(Nc1ccc([N+](=O)[O-])cc1O)Nc1ccc(Br)cc1Br +C=CC(=O)Nc1ccccc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2)ncc1Cl +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCCCNC(C)=O +O=C(Nc1ccc(C(F)(F)F)cc1)N1CCN(c2ncc(C(O)CO)cc2Cl)CC1 +COC(=O)CCN1C(=O)c2ccccc2NC1c1ccc(Cl)cc1 +CC(C)Oc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cc1 +COc1cc(-c2ccc(C)cc2)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +Clc1ccc(Sc2oc(C3CCOCC3)nc2-c2ccc(N3CCNCC3)nc2)cc1 +O=C(c1cccc(-c2ccco2)c1)N1CCCC(F)(C(=O)Nc2ccc(Cl)cc2)C1 +C=CC(=O)NCCCn1c(-c2nc(-c3cnn(C4CCN(C)CC4)c3)cnc2N)nc2ccccc21 +Cn1nccc1-c1cc(NC(=O)Nc2cccc(F)c2)ccc1OCCN1CCCCC1 +Cc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 +COc1ccc(C=CCN2CCN(C(=O)CCCCC(c3ccccc3)c3ccccc3)CC2)cc1 +CC1CCCN1CCCOc1ccc(N2CCN(C(=O)c3ccc(F)cc3F)CC2=O)cc1 +Cc1cc(-c2sc(Cc3ccc(Cl)cc3)nc2C)ccc1C(N)=O +C#CC1CCC(C#N)N1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2 +COc1cc(-c2cc(=O)c3c(OC)c(OC)c(OC)cc3o2)cc(OC)c1OC +Cn1nnc(Cc2ccc3c(c2)c(C2CCN(CCN4CCNC4=O)CC2)cn3-c2ccc(F)cc2)n1 +O=C(C1CC(N2CCN(c3nnnn3-c3ccccc3)CC2)CN1)N1CCSC1 +NCCn1nc2c3c(c(NCCNCCO)ccc31)C(=O)c1c(O)ccc(O)c1-2 +FC(F)(F)c1nncn1C1CCN(Cc2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)CC1 +CCC1C=CC(O)C(C)OC(=O)C(C)=CC2C(=O)NC3=CC(=O)c4c(cc(C)c(O)c4C(=O)CC1)C32O +CCCCCC(O)c1ccc(N2C(=O)CCC2CCCc2ccc(C(=O)O)s2)cc1 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(NCc3ccccc3)cc2)cc1 +O=C(c1ccc(-c2ccccc2)[nH]1)N1N=C(c2cccnc2)CC1c1ccccc1O +Clc1ccc(Oc2ccc3c(NCCCNCc4ccco4)ccnc3c2)cc1 +C=CCN(CC=C)Cc1c(C(F)(F)F)nc2n(-c3c(C)cc(C)cc3C)c3ccccc3n12 +CN1CCN(c2ccc3[nH]c(-c4c(N)c5ccccc5[nH]c4=O)nc3c2)CC1 +CCc1cc(C2SCC(=O)N2CCCN(C)CCOc2ccc3c(c2)OCO3)cc(CC)c1O +O=C1CCCN1c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +N=C(N)NCCCn1cc(-c2ccc3ccc4ccc(-c5cn(CCCNC(=N)N)nn5)nc4c3n2)nn1 +O=C1CN2Cc3cc(OCCCc4nnnn4C4CCCCC4)ccc3N=C2N1 +CC(O)CCOc1cc2ncccc2cc1NC(=O)c1csc2cncnc12 +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4ccc(Cl)c(O)c4)cc3)nc2c1 +COc1c(C(C)(C)C)cc(CN2CCN(CCCCCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1C(C)(C)C +CCC1COc2cccc3c(=O)c(C(=O)NC4CCCCC4)cn1c23 +COC(=O)C(Cc1cccc(C(=N)N)c1)C(C)NC(=O)c1ccc(-c2ncc[nH]2)cc1 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+CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2CCCC)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1 +O=C(CSc1nnc(-c2ccccc2)c(-c2ccccc2)n1)c1c[nH]c2ccccc12 +CCCCN(CC)Cc1c(CC)nc2cc(C=CC(=O)NO)ccn12 +Cc1c(CC(=O)OC(C)C)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)c(F)c1 +CC(=O)CC1Cc2sccc2C2(CCN(Cc3ccccc3)CC2)O1 +COc1cc(CN(CC2CC2)C(CC(=O)O)c2ccc3c(c2)CCO3)ccc1OCCn1c(=O)ccn(C)c1=O +COc1cc(CN=C(S)NC(c2ccccc2)c2ccccc2)ccc1O +COc1ccc(C2C(c3ccc(C)cc3)CC3CCC2N3C)cc1 +N#Cc1cc(CN2C(=O)N(Cc3ccccc3)C(CCc3ccccc3)C(O)C2Cc2ccccc2)ccc1F +Cc1ccc(C2CCC(N3CC(NC(=O)CNc4nn(C)c5ccc(C(F)(F)F)cc45)C3)CC2)cn1 +COc1ccc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2c1C1CCCC1 +COc1cc(Cl)ccc1OCC1CN(Cc2ccc(Br)cc2)CCCO1 +CC12CCC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(OC(=O)c1ccco1)C(=O)CSc1nc2ncccc2s1 +Cn1cc(-c2cc3c(-c4cccc(N5CCC(CN)CC5)n4)n[nH]c3cn2)cn1 +COc1ccc(C(=O)Nc2nc(-c3ccccc3)cs2)cc1 +CC1=NC(C)=C(C(=O)OCCCN2C(=O)c3ccccc3S2(=O)=O)C(c2ccccc2Cl)C1=C(O)OCC1CCCO1 +C=C1C(C=CC(=O)OC)=C(C(=O)O)N2C(=O)C(=Cc3ccccn3)C2S1(=O)=O +O=C(O)c1c(CCCOc2ccc(Cl)c3ccccc23)c2cccc3c2n1CCS3 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+O=S(=O)(NCCCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc2cccnc2c1 +Cc1ccc(OCc2ccc(F)cc2)c(-c2ccc(C)n2-c2ccc(F)c(C(=O)O)c2)c1 +O=C(O)CC1(CCc2ccccc2)C2CC3CC(C2)CC1C3 +CCC1CCCC(C2(Cc3nc(CN4CCCC4)no3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +Cc1noc(C)c1CC(=O)NCc1ccc(F)c(Cl)c1F +C=CCCCCC(NC(=O)c1cccc(O)c1OCCC=C)C(O)CN(CC(C)C)S(=O)(=O)c1ccc(OC)cc1 +CN(N=Cc1ccccc1C(=O)O)c1nc(-c2ccccc2Cl)cs1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC=O)c1=O)C(=O)C(F)(F)F +CC(O)CNc1ncnc2oc(-c3ccccc3)c(-c3ccccc3)c12 +CC(C(=O)N1CCOCC1)N1CCC(NS(=O)(=O)C2=Nc3ccc(Cl)cc3C2)C1=O +Cc1cccc(C)c1-c1cccc(COc2ccc(CCC(=O)O)c(F)c2)c1 +CCCCN(NC(=O)C(CCC)N1CCC(CCCN=C(N)N)(NCCCC2CCCCC2)C1=O)C(=O)OCC +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(C(=O)NC#N)cc2)ncc2ccccc12 +O=C(Nc1ccccc1)N1CCN(Cc2ccc(Br)c(Br)c2)CC1 +Cn1c(=O)ccc2cc(NS(=O)(=O)c3ccc(C#N)c(Cl)c3)ccc21 +COC(=O)C1(C)CCCC2(C)c3cc(O)ccc3CCC12 +CCCN(C)C(=O)CCCCCCCC1CC2CC(=O)CCC2(C)C2CCC3(C)C(O)CCC3C12 +CCCN1CCN(CCCOc2cc3ncc(C#N)c(Nc4cc(OC)c(Cl)cc4Cl)c3cc2OC)CC1 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+COc1cc(OC)c(-c2cc3ccccc3[nH]2)cc1C=CC(=O)c1ccc(C(=O)O)cc1 +O=C(NC1CCCCC1CO)c1cccc(C2CCCCC2)n1 +CCOC(=O)c1ccc2c(C(=O)NCc3ccc(F)cc3)c(C(C)C)n(Cc3ccccn3)c2c1 +Cc1cc(Nc2cccc(Cl)c2)n2nc(C(C)(F)F)nc2n1 +CCCc1nc2c(C)ccnc2n1Cc1ccc(-c2cccnc2-c2nn[nH]n2)cc1 +CC(C)C(N)CNc1nc(-c2ccncc2)nc2c(Br)csc12 +CC(Nc1cc2c(-c3cc(Cl)cc(CCC(N)=O)c3)noc2cn1)c1ccccc1 +COC(=O)C(NC(=O)c1c2c(nc3ccccc13)-c1ccccc1CC2)c1ccccc1 +NC(CC(=O)NC1(c2cccc(-c3cncs3)c2)CCS(=O)(=O)CC1)Cc1ccccc1F +CC(c1ccc(C(F)(F)F)cc1)N1CCC(CCC(N)=O)(c2ccc(F)cc2)OC1=O +CC1CC(=O)Nc2cccc(-c3ccc4c(c3)c(C3CC3)nn4C)c2N1 +O=C1OCCc2cc(CCN3CCN(CC(O)c4ccc5c(c4C(F)(F)F)COC5=O)CC3)ccc21 +CS(=O)(=O)c1cc(C(=O)N=C(N)N)c(N)cc1N1CCCC(O)C1 +CN1CCN(c2ccc(Nc3cc(-c4cccc(-n5ccc6cc(C7CC7)ncc6c5=O)c4CO)cn(C)c3=O)nc2)CC1 +O=C(NC1CCN(C(=O)CCc2cccnc2)CC1)C(c1ccccc1)C1CCCCC1 +Cc1cc(NC(=O)CCl)sc1-c1nnc2n1Nc1nc3ccccc3nc1S2 +CC(C)Oc1ccc(S(=O)(=O)N2CCN(c3ccc([N+](=O)[O-])c(OCC(=O)O)c3)CC2)cc1 +Cc1ccc(-c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C4CC4)cc3F)n2)cc1 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+O=c1ccn(CC=CCOC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1 +NS(=O)(=O)Oc1ccc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)c(F)c1 +O=C1CC(CN2CCN(Cc3ccccc3)CC2)Cc2ccccc21 +COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N2CCN(CC3CCN(C)CC3)CC2)c(C)c1 +CCc1ccc(CC)n1-c1c(C)c(C(=O)NC2CCCCC2)nn1-c1ccc(Cl)c(Cl)c1 +Cn1cncc1C(O)(c1ccc(C#N)cc1)c1cc2cc([N+](=O)[O-])cc(-c3ccccc3F)c2o1 +O=C(NC(=S)Nc1ccc(NC(=O)c2cccs2)cc1)c1ccco1 +Cc1ccc(NC(=O)c2ccc(CN)cc2)cc1Nc1nccc(-c2cccnc2)n1 +O=C(c1cccnc1)N1CCc2nc(-c3cc4cc(F)ccc4[nH]c3=O)[nH]c2C1 +CCCC(=O)N1CCc2c(nc(C)n2C2CC3CCC(C2)N3CCCN(C(=O)Nc2ccc(C)cc2)c2ccccc2)C1 +CN(C(=O)c1cc(-c2cccc(O)c2)sc1-c1cccc(O)c1)c1cccc(O)c1 +Cc1cc(CNc2ccc(Cc3c[nH]c4ncc(Cl)cc34)c(F)n2)ccn1 +Cc1cc(S(=O)(=O)NC(=N)NNc2ccc(S(N)(=O)=O)cc2)c(SCc2cccc(C(F)(F)F)c2)cc1Cl +COc1ccc(-c2cc3ncccc3c(OCC3CCC(=O)NC3)n2)cc1OC +Cc1[nH]sc2ncc3c(=O)n(-c4ccc(Cl)cc4)nc3c12 +Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(C(F)(F)F)cc1 +Cc1ccc(C)n2nc(CCc3nc(-c4cccnc4)cn3C)nc12 +Cc1ccc(O)c(Cn2c(NC3CCN(CCC(C)C)CC3)nc3c(C)cccc32)n1 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+CNc1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2c1COC(C)(C)C2 +N#CC1CC(NCC(F)(F)F)CCC1n1cc(C(N)=O)c(Nc2ccc(Cl)cc2)n1 +Cn1c2ccccc2c2cc(CCOc3ncccc3-c3ccc(Cl)cc3)cnc21 +CC(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1 +O=c1[nH]c(=O)n(C2COC(CO)O2)cc1C=CI +COC1(c2cc(OCc3ccc4c(ccc(=O)n4C)c3)cc(F)c2C)CCOCC1 +COC1COCCC1NC1CCC(C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)(C2CCOC2)C1 +CCC(Nc1cccc(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 +O=C1C2CCCC2N1c1ccc(C#Cc2ccccc2)cn1 +CC(CCC(=O)Nc1ccc(S(N)(=O)=O)cc1Br)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C +COCCOCC1(C(=O)Nc2cccc(OC(=O)N(C)C)c2)CCN(c2ncnc3[nH]cc(C)c23)CC1 +CCc1cc(CNC)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 +O=C1C=C(c2cc[n+]([O-])cc2)S(=O)(=O)c2ccccc21 +Nc1ncnc2c1c(-c1cccc3[nH]ccc13)nn2C1CCCC1 +COc1ccc(OC)c(CNC(=O)c2ccc(Oc3ccc(C(C)(C)C)cc3)cc2)c1 +COc1ncccc1-c1cccn2nc(Nc3ccc(C4CCN(CC(=O)N(C)C)CC4)cc3)nc12 +CC(C)N(Cc1cccc2c1OC(C)(C)C=C2)C(=O)c1ccc(-c2ccccc2)cc1 +CCOC(=O)c1cc(N2CCN(C)CC2)nc2ccccc12 +C[N+](C)(CCOc1ccccc1)CC1COC(c2ccccc2)(c2ccccc2)O1 +O=C(Nc1ccccc1CCO)NC1CCN(Cc2ccc3cc(F)ccc3c2)C1 +CCC(O)c1c(F)cncc1-c1cnc2c(c1)CCCN2C(N)=O +CNCc1cn(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)nc1C(F)(F)F +CN(C)C1CCc2c(c3ccccc3n2S(=O)(=O)c2ccc(Br)cc2)C1 +CN=C(S)OCC1OC(n2cnc3c(NC4CCOC4)ncnc32)C(O)C1O +CCCCCCCN1C(=O)NC(c2ccc(Br)cc2)(c2ccc(Br)cc2)C1=O +CCOC(=O)c1cc2c(CC)c3c(nc2cn1)-c1cc2c(c(=O)n1C3)COC(=O)C2(O)CC +CC1CCC(C(=O)N(c2ccc(Oc3ccccc3C(C)(F)F)cc2C(=O)O)C(C)C)CC1 +CCCc1nnc2n1CCc1c(CC)nn(C3CCCC3)c1-2 +CCN(CC)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3C(=O)c2ccc3c(c2)OCO3)cc1 +COc1cc(NC(=O)Nc2cccc3c2C2CCCCN2C3=O)nc2ccccc12 +NC(=O)c1ccc(-c2ccc3c(c2)nn2cc(-c4ccccc4)c(-c4ccc(C5(N)CCC5)cc4)nc32)cc1 +CCNS(=O)(=O)Oc1cc(C(C)(C)C)c(SC2=C(O)OC(CCc3ccccc3)(C(C)C)CC2=O)cc1C +CN(C)CCCN1CCSc2cc(N=C(N)c3cccs3)ccc21 +N#Cc1cc(-c2ccnc(Nc3cncc(-c4cccnc4)c3)c2)ccc1OC1CCOCC1 +COc1cc(-c2nnc3n2CCOC3c2ccc(Cl)c(Cl)c2)ccc1-c1cnc(C)o1 +Cc1ccsc1C(=O)Nc1cccc(Oc2ccnc(-c3cc(C(=O)O)c[nH]3)c2)c1 +O=C(O)c1ccccc1C(=O)N1CCC(N2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)CC1 +COc1cc(-c2ccc(C(=O)N(C)C)cc2)cc(C=O)c1O +COCCNc1cc(Nc2nccc(-c3cnc(N4CCC(F)C4)c(C#N)c3)n2)ccn1 +CCCC1CN(C(=O)c2cc3cc(C#N)ccc3[nH]2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 +CC(NC(=O)Nc1ccon1)c1ccc(OC2CCN(c3ccnc(N4CCOCC4)n3)C2)cc1 +CC(Nc1ncc2ncn(-c3cc(C4CC4)[nH]n3)c2n1)c1ccc(F)cn1 +CCCS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c(-c3cccs3)nn(CCC(C)C)c1=O)N2 +Cc1nc2cc(-c3c(C)noc3C)cc(-c3c(C)n[nH]c3C)c2[nH]1 +Cn1cc(S(=O)(=O)NCCOc2ccc3c(c2)C(C2(c4ccc(Cl)cc4)CC(F)(F)C2)NCC3)cn1 +CCCC#Cc1nc(N)c2ncn(C3OC(C(=O)NCC)C(O)C3O)c2n1 +CC(C)(NC(=O)c1ccc2nc(NC3CCC(O)CC3)c3nccn3c2c1)c1ccccc1 +CCCCCCCCCCc1ccc[n+](CC(P(=O)([O-])O)P(=O)(O)O)c1 +CC(C)c1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O +CCC(CC)ON(CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)S(=O)(=O)c1ccc(OC)cc1 +CCOc1cccc(NC(=O)c2ccc(N3CCCC3)c(C(F)(F)F)c2)c1 +COc1cc2ccccc2cc1C(=O)C(=NC1CCCC1)n1ncc(C#N)c1N +CC(Oc1cc(-c2cccc(S(C)(=O)=O)c2)cnc1N)c1cc(F)ccc1-n1nccn1 +Cc1cccc(C)c1NC(=O)c1ccc(-c2ccsc2)o1 +O=S(=O)(Nc1ncns1)c1ccc2c(-c3ccc(Cl)cc3C3=CCNCC3)cccc2c1 +O=C1NCCn2c(-c3ccc(F)cc3)cc3cccc1c32 +COc1cc(OC)cc(N(CCCN2CCC(C3CC(C)OC(C)C3)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)Nc3onc(C)c3C)cc2)o1 +NC(=O)c1c(Nc2ccc(N3CCNCC3)cc2OC(F)(F)F)nc(Cc2c(Cl)cccc2Cl)c2nc[nH]c12 +COc1cccc(-c2ccc3c(c2)CCc2c-3nc3ccc(F)cc3c2C(=O)O)c1 +CN1C2COCC1CC(OC(=O)c1cn(-c3cnccn3)c3ccccc13)C2 +Cc1cn(CCCn2c(=S)[nH]c3sc(Cc4ccccc4)cc3c2=O)cn1 +CCCCCC=CCC1(O)C=C(Cl)C(=O)C1CC(OC(C)=O)C(CCCC(=O)OC)OC(C)=O +CC1CCc2cc(-c3ccnn3C)ccc2N1C(=O)c1ccc(O)cc1O +CC1=C(Sc2cccc(Br)c2)C(COCCO)C(=O)NC1=O +CCOC(=O)c1cn(Cc2cccc(Cl)c2F)c2nc(N3CCN(c4nc5ccccc5o4)CC3)ccc2c1=O +O=C(Cc1cccc2ccccc12)Nc1cn(C2CC(NC(=O)c3ccccn3)C2)cn1 +COc1cc2c(OC3OC4COC(C)(C)OC4C(O)C3O)c3c(c(-c4ccc5c(c4)OCO5)c2cc1OC)C(=O)OC3 +O=C(Nc1nc2cccc(-c3ccc(CNC4CCS(=O)(=O)C4)cc3)n2n1)C1CC1 +N#CC1CCCN1C(=O)CNC1CCC(Nc2ccc(C(F)(F)F)cn2)CC1 +CCOc1ccc(OC)c(C(=O)C=Cc2ccc(O)c(O)c2)c1 +CC1CCc2cc(-c3nc4ccc(Cl)cc4cc3CO)ccc2N1C(=O)c1ccc(O)cc1O +CCOc1ccc(Cl)c(-c2nnc3c(C)nc4ccc(CN5CCOCC5)cc4n23)c1 +Cc1cc(Oc2cncnc2)cc(C(=O)Nc2cc(F)ccn2)n1 +C=CCCC(=O)OC1CCC2(C)C(CCC3(C)C2CCC2C4C(C(=C)C)CCC4(C(=O)O)CCC23C)C1(C)C +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(Cc1nc(-c2ccccc2)cs1)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +C=C1C(=O)OC2CC(C)C3C(OC(C)=O)CC(O)C3(C)C(OC(C)=O)C12 +CN(C)c1ncnc2c1c(I)cn2C1OC(CO)C(O)C1O +CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(SCC(=O)O)c(O)c3ccccc23)cc1 +CN(CC#N)CC1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)CC1 +CC1CC(C)(C)NC(CCOP(=O)(OCC2OC(n3ccc(=O)[nH]c3=O)CC2O)N(C)CCBr)O1 +CN(C)CCCN1C2=C(C(=O)Nc3ccccc3F)C(=O)CCN2c2ccc(F)cc21 +Cn1c2nc3ccccc3c-2c(NCCc2c[nH]c3ccccc23)c2cc(Cl)ccc21 +CC1(c2ccc(CCC(=O)O)cc2)c2ccc(O)cc2CCN1c1ccc(F)cc1 +FC(F)(F)c1cc(COC2CCC(CN3CCCCC3)C2c2ccccc2)cc(C(F)(F)F)c1 +O=c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)nn1-c1cc(Cl)ccc1Cl +COc1ccc(C(=O)C2C(=O)C(=O)N(c3nc4cc(OC)ccc4s3)C2c2ccccc2OCCO)cc1 +O=C(NC1CCCC1Nc1ncc(C(F)(F)F)cc1Br)c1ccccc1-n1nccn1 +CC(NC(=O)C1CC(S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1ccnc(C#N)n1)C(F)(F)F +COc1ccc(-n2nc3c(N4CCC(C(=O)N5CCCCCC5)CC4)nnc(C)c3c2C)cc1 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+CC(C)C1CN(CC2COCCN2)C(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1 +O=c1c(CN2CCN(Cc3ccccc3)CC2)coc2ccccc12 +CCC(C)c1ccc(N2C(=O)c3ccccc3NC2c2ccc(C(C)C)cc2)cc1 +CC(C)(O)c1ccccc1CCC(SCC1(CC(=O)O)CC1)c1cccc(C2CC2c2ccc3sc(Cl)c(Cl)c3n2)c1 +Cc1cc(O)c(Cl)cc1-c1ccc2ncc(C(=O)C3CC3)c(N3CCC(CN(C)C)CC3)c2c1 +Cc1ccncc1CN1CCc2c(sc3ccc(F)cc23)C1 +CNC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1O2 +CC(=O)c1c(C)c2cnc(NC3CCCCN3c3cccnc3)nc2n(C2CCCC2)c1=O +CS(=O)(=O)Nc1cccc(-c2ncc(-c3ccc(Oc4ccccc4)cc3)c3c(N)n[nH]c23)c1 +CCC(C)C(N)CN(C(=O)C1CC1c1ccsc1)c1ccc(-c2ccccc2)cc1 +CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2(C#N)CCCCC2)cc1F +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cccc(N)c2)c1 +CN1CCN(c2nc(NCc3cccs3)c3cc(Cl)ccc3n2)CC1 +COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2ccc(C(=O)O)cc2)cc2c1OCCO2 +COCCc1nnc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)s1 +CCc1nc2cc(C=CC(=O)NO)ccc2c(=O)n1CCc1ccc(F)cc1 +CC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12 +CNC(=O)COc1ccc2nc(CC(C)C)c(CN)c(-c3ccc(C)cc3)c2c1 +O=C(O)c1cccc(NC(=O)c2[nH]c(C3CC3)nc2CCC23CC4CC(CC(C4)C2)C3)c1 +NCCCCC1C(=O)Nc2ccc(O)cc2C(=O)N1C(C(=O)NCC(=O)O)c1cccnc1 +CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc2ccccc21 +Cc1ccc(C(=O)Nc2nccc3ccccc23)cc1S(=O)(=O)N1CCCCC1 +O=C1NCCc2c1ccc1[nH]cc(CCNCc3ccccc3)c21 +CCn1cnc2c(Nc3ccc(P(C)(C)=O)cc3)nc(C(C)C)nc21 +C#CCN(Cc1ccc2nc(CC#N)nc(O)c2c1)c1ccc(C(=O)NCc2cccc([N+](=O)[O-])c2)cc1 +CCOc1ccc(C(=O)Nc2ccc(C3CNCCO3)cc2F)cn1 +O=C1NC(=O)c2cc(Nc3cccc(O)c3)c(Nc3cccc(O)c3)cc21 +C=Cc1ccc2c(NC(C)c3ccc(NC(=O)c4ccc(Cl)nc4)cc3)nc(N(C)C)nc2c1 +CN(C)C1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1 +CN(CCc1cc(CCC(=O)O)cc(Cc2cccnc2)c1)S(=O)(=O)c1ccc(Cl)cc1 +CCn1cnc2c(Nc3cccc(Cl)c3)nc(NCCO)nc21 +CC=C1NC(=O)c2csc(n2)CNC(=O)CC(C=CCCSC(=O)CCCCCCC)OC(=O)C(C(C)C)NC1=O +COC1(C#CC(O)(c2ccccc2)c2ccccn2)CN2CCC1CC2 +COCCOCCOc1ccc(S(=O)(=O)N(CC(=O)NN=C2C(=O)Nc3ccccc32)c2ccc(Cl)cc2)cc1 +CC1Cc2c([nH]c3cc(F)c(F)cc23)C2(N1)C(=O)Nc1ccc(Cl)cc12 +O=C(NC1CC2COCC(C1)N2)c1cn(CC(F)(F)F)c2ccc(F)cc12 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+NC1CC(N2Cc3nn4c(C(F)(F)F)ccnc4c3C2)CCC1c1cc(F)c(F)cc1F +Cc1cc(N2CCOCC2)nc(N(CCCNc2ccnc3cc(Cl)ccc23)Cc2ccco2)n1 +O=C(CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)NC1CCOc2cc(CNC3CCCCC3)ccc21 +O=C(O)c1ccc(CN(CCC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 +Cc1nn(Cc2cccc3cccnc23)c2cc(CC(=O)O)ccc12 +CC1CCC(NC(=O)C(CC2(C)CCCCC2)NC(=O)c2ccco2)C(=O)CN1C(=O)c1ccccn1 +NS(=O)(=O)c1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +O=C(Nc1ccc(OC2CCN(C(=O)C3CCC3)C2)cc1)N1Cc2ccncc2C1 +Cc1cc(O)c(CN2CCCC2)c2c1C(=O)C(=Cc1ccco1)O2 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)c2ccccc2C(F)(F)F)cc1 +CC(C)CCOc1ccc2c(c1)C1OCCCC1C(C1CCCC1)N2 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1-c1ccn(C)c(=O)c1 +CC(C)c1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1 +CCCCCn1c(C)c(C(=O)c2ccc(OCC)c3ccccc23)c2ccccc21 +Nc1cc(C2CCC(CNS(=O)(=O)c3ccccc3[N+](=O)[O-])CC2)nn1-c1cccc(C(F)(F)F)c1 +Clc1ccc(-c2[nH]c3ccccc3c2C=NNC2=NCCN2)cc1 +CCc1nn(Cc2ccc(C(=O)Nc3ccc4ccccc4n3)cc2)c(CC)c1CC(=O)O +COc1ccc(Oc2c(C)[nH]c3cc(S(C)(=O)=O)ccc23)cc1 +O=C(NC(c1ccc(F)cc1)c1ccc(F)cc1)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1 +CC(Nc1cc(NCCOc2ccc(F)cc2)ncn1)c1ccccc1 +CC(C)(CC(O)(Cc1ccccc1)C(=O)Nc1ccc2c(c1)COC2=O)c1cc(F)ccc1O +O=C(CN1CCN(c2ccc(F)cc2)CC1)Nc1ccc2c(c1)Cc1c-2nc(O)c2ccccc12 +Nc1nc(O)c2nn(-c3cccc(C(=O)NCc4ccccc4Sc4ccccc4CO)c3)nc2n1 +C=C(C)CN1CCC23c4c5ccc(O)c4OC2c2ncc(-c4ccc(Cl)cc4)cc2CC3(O)C1C5 +Cc1ccc(S(=O)(=O)n2c(N)nc3ccccc32)cc1 +CC(C)(O)COc1ccc(C(F)(F)F)cc1C(=O)N=c1sc2ccncc2n1CC1CCC1 +CC(=O)c1cnc2ccc(-c3ccc4nc[nH]c4c3)cc2c1Nc1ccc(OCCN(C)C)nc1 +CCCCN(CC)c1nc(C)nc2c1n(C)c(=O)n2-c1c(C)cc(C)cc1C +Cc1nc(N2CCC(N3CCOCC3)CC2)nc2ccc(NC(=O)C=Cc3ccc(Cl)cc3)cc12 +O=P(O)(O)C(F)(Cc1cncc(-c2cn[nH]c2)c1)P(=O)(O)O +CCOc1ccc(S(=O)(=O)N(CC)CC)cc1-c1nnc2c(n1)c(C)nn2C +O=C(c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1)N1CCCCC1 +O=C1NCCc2c(-c3ccccc3Cl)[nH]c3cccc1c23 +Cc1cc(C)cc(Nc2nccc(-c3cnn4ncccc34)n2)c1 +CC(C)CC(NC(c1ccc(-c2ncccn2)cc1)C(F)(F)F)C(=O)NCC#N +CCNC(=O)c1ccc2nc(C)c3nnc(-c4ccccc4Cl)n3c2c1 +CCOC(=O)C=CS(=O)(=O)c1ccc(NC(C)=O)cc1 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+CNCC1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)C1 +CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1cccc(OC)c1n2CCF +O=C(C=Cc1ccc(S(=O)(=O)n2ccc3ccncc32)cc1)NO +CN1C(=N)NC(C)(c2sc(-c3cc(-c4nnco4)ncc3F)cc2F)CS1(=O)=O +O=C(O)Cc1cccc(NC(=O)CCC(NC(=O)c2cc(Cl)cc(Cl)c2)C(=O)N2CCC3(CCCC3)CC2)c1 +Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(S(C)(=O)=O)cc1 +CN1CCN(C(=O)c2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3)o2)CC1 +O=C(NC1c2ccccc2CC1O)C(OCC=CBr)C(O)C(O)C(OCC=CBr)C(=O)NC1c2ccccc2CC1O +N#CC(C#N)=C1C(=O)Nc2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc21 +Cc1cc(Br)ccc1CNCC(NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1N)C(=O)NC(C)(C)C +CC1CN(c2noc(C3CC3)n2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Cc1ccc(-c2nccnc2C2CN(c3ncc4ccccc4n3)C2)cc1 +O=C(O)C1NC2(CCCCC2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(Cl)c1F +CCCCCCCNC(=O)Oc1ccc2c(c1)CN(C)C(c1c(Cl)cccc1Cl)N2C +COc1cc(-c2cnc(NC(C)c3ccc(F)cc3)nc2)ccc1-n1cnc(C)c1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OCCc2ccccc2)C1c1[nH]cnc1Cl +Oc1ccc2c(-c3ccc(F)cc3)c(Oc3ccc(Cl)cc3)sc2c1 +CN1C(=N)NC(c2cccc(-c3cncc(F)c3)c2)(C2CC2)C1=O +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(I)cc1 +Cc1ccc(S(=O)(=O)Nc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)cc1 +CN1CCCC1CCNCC1CCN(c2ncnc3scc(-c4ccccc4)c23)C1 +CC(=O)CCCCCC(NC(=O)C1CCCCN1C)C(=O)Nc1nc(-c2ccccc2)cs1 +CC(c1ccc2ncccc2c1)c1nnc2ccc(-c3ccc4c(c3)OCCO4)nn12 +CCC(NCC1Cc2cccc(c2)OCCNC(=O)c2cc(cc(N(C)S(C)(=O)=O)c2)C(=O)N1)C(=O)NCC(C)C +CN(C)C1CCc2c(c3cc(F)ccc3n2S(=O)(=O)c2ccccc2Br)C1 +CSc1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1 +N#Cc1ccc(Nc2nccc(C(=O)c3c(F)cc(F)cc3F)n2)cc1 +O=CC(Cc1ccccc1)NC(=O)C1CCCN1S(=O)(=O)c1cccc2ccccc12 +O=C(NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1)C(F)(F)F +c1cc2[nH]nc(-c3cnn(C4CCOC4)c3)c2c(OC2CCOCC2)n1 +CNCC(C)(C)Cn1c(C(C)(C)C)cc(C(=O)Nc2cccc(C(F)(F)F)c2)c1C +Brc1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cc1 +O=C(c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1)C1CC1 +Cc1cccc(NC(=O)NC(CS(=O)(=O)Cc2ccccc2)C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CN(C)c1ccc2cc(C(=O)NCCCCCC(=O)Nc3ccccc3N)[nH]c2c1 +O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)ccc2n1CC[S+]([O-])c1nnc[nH]1 +C=CCSc1nc2sc3c(c2c(=O)n1-c1ccccc1)CCN(C)C3 +Cc1[nH]nc(N)c1-c1nc2cc(F)c(Br)cc2s1 +COc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 +CC(C)CCN1CCC2(CC1)OCCc1c2cnn1-c1ccccc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(=O)O)cc4)cc3)[nH]c2n(CCC)c1=O +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4ccc(OC)cc4[nH]3)CC3CC123 +Cc1ncsc1C(=O)N(Cc1cncc2c(F)cccc12)c1cccc(Cl)c1 +COc1ccc(CNc2nnc(NCc3ccccn3)c3ccc(C#N)cc23)cc1Cl +CN(C)CCOc1ccc(Cn2c3ccccc3c3sc4cc(O)ccc4c32)cc1 +O=C(NC(C(=O)O)c1ccc(O)cc1)c1cc2[nH]c(-c3ccco3)c(C3CCCCC3)c(=O)n2n1 +COc1ccc2nc(C=CC3C4CCCCC4CC4C(=O)OC(C)C43)ccc2c1 +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(Nc2ccc(CCNC(=O)OC(C)(C)C)cc2)n1 +CC(C)CN=C(Nc1cccc(C(=CCCCC(=O)O)c2cccnc2)c1)Nc1nn[nH]n1 +N#CCCN(CCC#N)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +Nc1cccc(SCC2COC(CCc3ccc(Cl)cc3)(Cn3ccnc3)O2)c1 +Cc1cc(C#Cc2cn(-c3cccc(C#N)c3)c(C)n2)ccn1 +COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3cccc4c(O)c5cccc(F)c5nc34)cc1)CC2 +O=c1nc(OCCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)[nH]cc1Cc1cncnc1 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +CC1(c2cc(NC(=O)c3ncc(C(F)F)cc3Cl)cc(F)c2F)CC(C(F)(F)F)OC(N)=N1 +N#Cc1cccc2c1C=Cc1ncc(-c3cccc(F)c3)cc1C2O +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 +CCCN(CCC)C1CCc2ccc3[nH]cc(CN(C)C)c3c2C1 +Fc1c(Cl)cccc1-c1nc2ccn(Cc3ccc(Br)cc3)cc-2n1 +CC1(C)CCC2(CCCCCCCCCCC(=O)O)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3nc(OCCN5CCNCC5)ccc34)cc2)no1 +COc1ccc2c(c1)c(CCN(C)C)cn2S(=O)(=O)c1ccccc1Cl +CCCCC(NC(=O)C(NC(=O)C(NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(O)CC(=O)O +CN(C)CCNC(=O)c1cccc2nc3ccc4[nH]cnc4c3nc12 +CC(NC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2)C1CCCCC1 +Cc1c(CCN2CCc3nc(-c4ccc5c(c4)COC5=O)oc3C2)ccc2c1COC2=O +CC1OC(C#CC2CC2)(C(F)(F)F)c2c(ccc(F)c2F)NC1=O +COc1ccc2nc3cc(Cl)ccc3c(NCCCN(C)CCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1 +Cc1cc(C)cc(C(O)c2cc(Cl)ccc2OCC(=O)Nc2ccc(S(N)(=O)=O)cc2C)c1 +CS(=O)(=O)N1CCN(Cc2cn3c(Cl)c(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3n2)CC1 +N#Cc1nc(NCc2cccc(-c3ccoc3)c2)c2ncn(CCCO)c2n1 +CCCC1CC(OC)CC(C)=CC2CC(OC(=O)C=CCCc3coc(CCCNC(=O)OC)n3)CC(CC(=O)O1)O2 +COc1cc(OCc2cccc(OCc3ccc(I)cc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CC1=C(O)C(=O)C=C2C1=CC=C1C2(C)CCC2(C)C3CC(C)(C(=O)O)CCC3(C)CCC12C +O=C1NCc2cc(-c3n[nH]cc3CN3C4CCC3CN(c3ccc(C(F)(F)F)cn3)C4)ccc2O1 +CCCCCCC1(c2ccccc2)CC(=O)C(SCCc2ccccc2)=C(O)O1 +Clc1cnc2c(Nc3ccc(N4CCOCC4)cc3)nc(-c3cccnc3)cn12 +CN(c1ncnc2[nH]ccc12)C1CC(CS(=O)(=O)N2CCC(F)(F)CC2)C1 +Cn1cc(-c2cn(-c3ccnc4c3c(C(F)(F)F)nn4-c3ccc(C(N)=O)cc3NC3CCCC3)cn2)cn1 +CCCCN(CCCC)CCCOc1ccc(-c2cn3cccc(C)c3n2)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NC1CCN(c2ncc(F)cn2)C1 +CN(C)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +O=C(O)Cc1ccc(CCCC2(O)CCN(CC3CN(CC4CCCCC4)CC3c3ccccc3)CC2)cc1 +Oc1cccc(-c2cc(-c3ccccc3)c(-c3cccc(O)c3)s2)c1 +N#Cc1ccc(Cn2cncc2CN2CCN(C(=O)c3ccccc3)CCC2c2ccccc2)cc1 +CNC(=O)CN1CCC(Oc2cc3c(Nc4ccc(F)c(Cl)c4F)ncnc3cc2OC)CC1 +O=C1N(Cc2ccccc2)C(CCCc2ccccc2)C(O)C(O)C(CCCc2ccccc2)N1Cc1ccccc1 +O=c1[nH]nc2cc(CO)c3ccc(-c4ccncc4)cc3n12 +Nc1nccn2c(C3CCC3)nc(-c3cccc(O)c3)c12 +CN1CCC(c2cc(NC(=O)Nc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cn3)cc(C(F)(F)F)c2)CC1 +CC(=NNC(=O)c1ccccc1)C(=NNc1ccc(S(N)(=O)=O)cc1)S(=O)(=O)c1ccccc1 +Cc1ccc2c(c1)CCN2C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 +CCCCNc1ccc2ncc(-c3ccc(C(=O)NCC4CC(F)CN4)c(F)c3)n2n1 +CC(C)N(C(=O)C1C2CCCCC21)c1cc(C#CC(C)(C)C)sc1C(=O)O +Cc1cccc(C(=O)N2CCN(CCN3CCC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)c1 +Cc1cc(-c2nc(-c3ccc(OC(F)F)c(CO)c3)n3c2CCOC(C)C3)cc(C)n1 +NC1=NC(CF)(c2nc(NC(=O)c3nn(C(F)F)cc3Cl)ccc2F)CC(C(F)(F)F)O1 +Cc1nsc(S(=O)(=O)NC(=O)c2ccc(N3CCN(Cc4ccccc4-c4ccc(Cl)cc4)CC3)cc2)c1Cl +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1cccc(O)c1 +CC(=O)c1ccc(-c2nnn(-c3cccnc3)c2C)cc1 +COC1(c2cccc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCOCC1 +COc1cc(N)c(Cl)cc1C(=O)OC1CN2CCC1CC2 +CN(CCCNc1ccnc2cc(Cl)ccc12)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Fc1cc(OC2CCNCCC2F)c2nc(-c3nnc4ccccn34)ccc2c1 +Cc1nccc(Nc2ncc3c(n2)CN(C(=O)NC(C)c2ccc(Cl)c(Cl)c2)CC3)n1 +CCn1nnc(C2OC(n3cnc4c(NCc5cccc(F)c5)nc(Cl)nc43)C(O)C2O)n1 +O=C(OCc1ccc(Cl)c(Cl)c1)C1(c2ccc(Cl)c(Cl)c2)CCNCC1 +Cc1ccc(Nc2nc(Cl)nc(Nc3ccc(C#N)cc3)n2)c(Br)c1 +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc(N)c2)[nH]c1=O +Cc1c(CN(C)CC(O)c2cc[nH]n2)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12 +CCCN(CCC)C1CCc2c(ccc(C(O)Cc3ccccc3)c2OC)C1 +Cn1nc(C(F)(F)F)c(-c2ccc(F)cc2)c1NC(=O)Nc1ccccc1 +OC1(C(F)(F)F)c2ccccc2-c2c(-c3cnn(C45CC6CC(CC(C6)C4)C5)c3)cccc21 +O=C1C(N2CCC(c3ccc(O)cc3)CC2)CCCN1Cc1ccccc1 +Cc1ccc(C)c(C[S+]([O-])c2nc3ccccc3[nH]2)c1N +CC(C)CN1CCN(CCOc2ccc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)CC1 +CC1(c2ccccc2)CCCN(C(=O)NCCc2ccc3nccnc3c2)C1 +Cn1c2c(c3ccc(-n4ccc(-c5ccc(Cl)cn5)cc4=O)cc31)CCNC2 +CNC(=O)Nc1nc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(F)cc4)c3)cc2s1 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(CCC2CC2)C1 +NC1=NC2(c3ccc(F)cc3F)COC(c3ncc(F)cn3)CC2CS1 +CC(C)Oc1ccc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cc5ccccc5F)C4)cc23)cn1 +COc1ccc(S(=O)(=O)N2CCc3cccc(-c4ccc(O)cc4)c32)cc1 +N=C(N)c1ccc(CNC(=O)C2CCCN2C(=O)C(NS(N)(=O)=O)C(c2ccccc2)c2ccccc2)s1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1CC1CC1 +Cc1ccccc1C(C(=O)NC1CCCCC1)N(C(=O)Cn1cncn1)c1cccc(F)c1 +CN(Cc1n[nH]c(O)n1)C(COCc1cc(Cl)cc(Cl)c1)c1ccccc1 +COC(=O)CCCC=CCC1C(=O)C(C)(C)C(O)C1C=CC(O)Cc1cc2ccccc2s1 +CONC1=NC(=O)C(=Cc2cc(C(C)C)c(O)c(C(C)C)c2)S1 +CC1=CC(C)(C)C2(O)COC(c3ccc(O)cc3Cl)C1C2 +Cc1ccccc1Oc1cc(N2CCC(Oc3ncc(F)c(N)n3)CC2)ncn1 +Fc1ccc2c(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)[nH]nc2c1 +Nc1nc(Nc2ccc(C(=O)O)cc2)nc(OCC2CCCCC2)c1C=O +O=C1NC(=O)C(c2ccccc2[N+](=O)[O-])=C1Nc1cccc(O)c1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C(=O)c5ccccc5)cc4)cc3)cc2n(CCC)c1=O +COc1cc2nc(-c3ccc(C)c(Br)c3)cc(O)c2cc1-c1cnco1 +O=C(Nc1cc(CNC2CCCCC2)[nH]n1)Nc1cccc2c1C1CCCN1C2=O +CCC(CC)Oc1cc(C)c(-c2cc(-c3cnc(NC(=O)NC)s3)nc(-c3cnccn3)n2)c(C)c1 +COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C(C)c1ccccc1)CC2 +Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccn2)cc1-n1cc(-c2cncc(N(C)CCN3CCCC3)c2)nn1 +CCCCOC(=O)C1=CCC23CCC(C(C)(C=CC=C(C)C(=O)O)OC2=O)C3(OC(C)=O)CC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3cc(OCC4CC4(F)F)ncc3F)C2)cc1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1-c1ccccc1 +COC(=O)C1=C(c2ccc3ccccc3c2)CC2C(O)CC1N2C +CCC(CC)c1cc(C)n2nc(-c3cc4c(cc3C)OCO4)c(C)cc12 +CC(=O)N1C2C=C(CN3CCC(Nc4ccc5ccc(C(F)(F)F)cc5n4)CC3)CC1CCC2 +CC(NC(=O)C(=O)Nc1ccc2c(c1)CCC2)C(=O)NC(CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F +O=C(NO)c1ccc(NC2CCN(Cc3ccccc3)C2=O)cc1 +CN(C)C1CCN(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1 +CC(C)n1cc(Nc2[nH]nc3ccnc(OC4CCOCC4)c23)cn1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC1CNC(=O)CCCCOC(=O)C(O)C(CC2CCCCC2)NC1=O +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CO)C(F)(F)F)ncc23)ccn1 +CCCc1nc(-c2cc(N)ccn2)c(-c2ccccc2C)s1 +O=C1OC2(CCN(c3nc4cc(Br)ccc4[nH]3)CC2)c2ccccc21 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=NC#N)N2CCN(C)CC2)CCO1 +COc1cccc2c1CCN=C2c1sc2cccc(C)c2c1Cl +CC(=O)N1N=C(c2ccc(O)cc2O)CC1c1cccc(O)c1 +c1csc(C2CN3CCCC3c3cc(OCCCN4CCCCC4)ccc32)c1 +Cc1c(S(=O)(=O)NCCCN2CCN(c3noc4ccccc34)CC2)sc2ccc(F)cc12 +Cc1nc(C(=O)N2C3CCC2C(Nc2cnc(C(F)(F)F)cn2)C3)c(-c2ccc(F)cc2)s1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(CC(C)NC3CCCC3)c2=O)c1 +CSc1cc(F)c(F)cc1-c1ccc(OCc2cccc(C(=O)N3CCCC3C(=O)O)c2)cc1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCC(F)(F)CC3)n2)cc1OC(F)F +CC(C)CC(NC(=O)C(NC(=O)c1cccc(-c2ccccc2)c1)C(C)O)B(O)O +CCc1sc(SCc2cc(N3CCOCC3)cc(NCc3cccc(C)n3)n2)nc1CF +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccco3)cc12 +CNC(C)C(=O)Nc1cc(-c2nc(C)nc3nn(C)c(C)c23)cc(C#Cc2cccs2)n1 +Oc1ccc(OCC(O)CN2CCN(c3ccc(Cl)cc3)CC2)cc1 +CCCCOc1ccc(S(=O)(=O)N2CCC(NCC(O)c3ccc(O)c(NS(C)(=O)=O)c3)C2)cc1 +COc1cc(C=CC(=O)c2cccc(NC(=O)c3ccc(Cl)cc3Cl)c2)ccc1O +COc1cc(C(=O)N2C(c3nccs3)C(CO)CC2(CC(C)C)C(=O)O)ccc1C(C)(C)C +O=C(CCCCCCC(=O)Nc1ccc(-c2cn(CC(O)c3cccc(Br)c3)nn2)cc1)NO +CC(=O)OC(c1ccc(Br)cc1)C(Cn1ccnn1)c1ccccc1 +CCNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)nc3c2C(=O)N(CC)CC(C)(C)O3)cc1F +COC1CCN(C2CCC(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 +CS(=O)(=O)N1CCN(c2cc(-c3n[nH]c4ccc(-c5cnccn5)cc34)ncn2)CC1 +Cn1cc(-c2ccc(Cc3n[nH]c4ccc(C(=O)N5CCC(O)C5)cc34)cc2)cn1 +CN1C(=O)Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(OCc4ccccc4)c3)cc21 +Cc1cc2[nH]c(=O)c3cnn(C4CCOC4)c3c2cc1C(=O)N1CCC(OCC(C)(F)F)CC1 +Cc1c2c(cn1C)-n1c(C)nnc1C(CC(=O)N1CC3(CCS3(=O)=O)C1)N=C2c1ccc(Cl)cc1 +CC(C)Cc1cc(-c2ccc(CCNCC(O)c3ccc(N)nc3)cc2)ccc1C(=O)O +Nc1ccncc1C(O)CNCCc1ccc(-c2ccc(C(=O)O)c(OC3CCCCC3)c2)cc1 +CC12CCC(=O)C=C1NCC1C2CCC2(C)C(C(=O)N3CCNCC3)CCC12 +COc1cc2ncc(C(N)=O)c(Nc3ccccc3Br)c2cc1OC +Cc1cccc(C)c1-n1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n2c3ccccc3nc12 +Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2ccc(-n3cncc3C)cn12 +Cn1c(C2(C)CC2)cc(=NC(=O)c2cc(C(F)(F)F)ccc2OCC(C)(C)O)n1CC1CCCO1 +CN1CC2(C1)CN(C(=O)Cn1cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n1)C2 +N#Cc1ccc2c(c1)C(N1CCCC1=O)=CC(CF)(CF)O2 +CCCn1cc(C#N)c2ncnc(N3CCN(CCc4ccccc4)CC3)c21 +CCN1C2CCC1CC(c1ccnc3c(-c4ccc(Cl)c(OC)c4)c(-c4ccncc4)nn13)C2 +CC(C)Nc1ncc2c(n1)CN(C(=O)NCc1ccccc1)CC2 +COc1ccc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c2ccnn12 +Cc1cn(Cc2ccc(Cl)cc2Cl)c2c(-c3ccc(NS(=O)(=O)c4cc(Cl)c(Cl)s4)nc3)cc(F)cc12 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCN3CCOCC3)no2)cc1C#N +CC(C)(C)OC(=O)N1CCC(c2coc3c(N4CCCc5cc(S(C)(=O)=O)ccc54)ncnc23)CC1 +CCNC1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)NC(C)C)n3)c(OC)c2)C1 +Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3ccccc3)cc21 +CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1ccc(F)cc1 +O=C(c1ccccc1)N(c1ccccc1)C1CCN(Cc2ccccc2)CC1 +COC(=O)Cc1ccc(C#CC2(CN3Cc4ccc(OC)cc4C3=O)NC(=O)NC2=O)cc1 +COc1cc(OC)cc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)c1 +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)B(O)O +CC#CCOc1ccc(S(=O)(=O)NC(Cc2c(C)n(Cc3ccc(C#N)cc3)c3ccc(OC)cc23)C(=O)O)cc1 +CC1(F)CCN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CCN4CCCC4C3)n2)C1 +COc1cc(OC)cc(C(=O)N(CCN2CCC(OCC(=O)O)CC2)c2ccc(C)cc2)c1 +CCCCCCCCCCCCn1nnc(C(NC(=O)c2ccnc(SC)c2)c2ccccc2)n1 +FC(F)(F)c1ccc(C(NCC2CCCCC2)c2cccnc2)cc1 +CC(C)(Nc1nc(NO)nc(Nc2ccc3ncsc3c2)n1)c1ccccc1 +CC(c1nc(-c2ccc(S(C)(=O)=O)cc2)no1)C(N)C(=O)N1CCCC1 +CC1=CC(=O)N(Cc2c(F)cccc2F)S(=O)(=O)O1 +O=C(NO)c1ncc(CCc2ccc(F)cc2)c(CO)c1O +CC(C)(C)c1ccc(-n2cc(-c3cccc(NC(=O)CCCCCCC(=O)NO)c3)nn2)cc1 +Nc1nc(-c2ccco2)c2c(n1)-c1ccccc1C2=O +C=C1CCC2C(C)(C(=O)OC)CCCC2(C)C1CCc1ccc2c(c1)C(=O)C=CC2=O +Cc1nc(CO)nc(N2CC(C)N(c3ccnc(C(C)O)n3)C(C)C2)n1 +O=C1CCCCC1CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1 +O=C1C(=O)N(Cc2ccc(Br)cc2)c2c(Br)cc(Br)cc21 +O=C(C1CC(Oc2ccccc2)CN1)N1CCCN(C2CCC2)CC1 +CC(=O)NC(C)c1ccc(C#Cc2ccc3c(c2)CCO3)cc1 +Cc1cc2c(cc1N1C(=O)c3cccc4c(Cl)ccc(c34)C1=O)n(C)c(=O)n2C +COc1cc2cc(Cl)ccc2nc1-c1ccc(N(Cc2ccsc2)C(=O)c2ccc(O)cc2O)cc1 +CC(C)Oc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +COc1ccc(C2=NN(Cc3ccccc3)C(=O)CC2)c2cc(C(C)C)nn12 +COc1ccc(N(Cc2nc(-c3ccccc3)cs2)S(=O)(=O)c2ccccn2)cn1 +CC(CCC(=O)Nc1ccc(S(N)(=O)=O)cc1)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C +c1ncc(-c2cc3sc(N4CCC(N5CCCCC5)CC4)nc3cn2)cn1 +Cc1nn(C2CCCCC2)c2sc(C(=O)NCC(C)(C)CN3C(=O)CNC3=O)cc12 +COC(=O)CC1CCN(c2ccc(Nc3ncc4c5ccnc(F)c5n(C5CCCC5)c4n3)nc2)CC1 +Cc1nc2cnccc2n1CC1CCN(C(=O)CC(C)(C)c2ccccc2)CC1 +COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3ccccc3)c2cc1OC +Cc1cnn(CC(=O)Nc2cncc(C(=O)c3cn(C(C)C)c4ccncc34)c2)c1 +Brc1ccc(CCN(Cc2ccc(Oc3ccccc3)cc2)Cc2c[nH]cn2)cc1 +NC1CCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(F)c(O)c(Cl)c5)cc34)cn2)C1 +COc1ccc(C(C)(C)C)cc1NC(=O)c1ccc(C)c(Nc2ncnc3cnc(N4CCCN(C)CC4)nc23)c1 +O=C(Nc1ccc(C(F)(F)F)cn1)N1CC=C(c2ncc(CCO)cc2Cl)CC1 +Cc1c(C#N)ccnc1OC1CCC(C)N(C(=O)c2ccncc2-c2ccccc2)C1 +Cc1cncc(-c2c[nH]c3ncnc(N4CCCC(C)C4)c23)c1 +CS(=O)(=O)N1CCC(CCC(=O)Nc2ccc(F)c(F)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +O=C(NCc1ccccn1)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +Cc1ccc(-n2nc(C3CCN(S(C)(=O)=O)CC3)cc2NC(=O)c2cnn3cc(NC=O)cnc23)nc1 +N#Cc1cccc(S(=O)(=O)C2CCN(CCc3ccc(F)cc3F)CC2)c1 +[H]C([H])(c1ccccc1)N1CC(C)N(C(=O)Nc2cccnc2)C(C)c2ccncc21 +COCCC(=O)Nc1cccc(-c2n[nH]c3ccc(-c4nn[nH]n4)cc23)c1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCc3ccnc(N)c3)c3ccccc23)cc1 +Nc1nc(-c2cccc(C(=O)N3CCN(Cc4ccccc4)CC3)c2)cn2nc(-c3ccco3)nc12 +Nc1ccc(C2CCCCC2)nc1C(=O)Nc1cnccc1C1CCCC(N)C1 +O=C(Nc1ccc(CCO)cc1)C1CCN(C(=O)Cn2c(=O)sc3ccc(Cl)cc32)CC1 +CC(C(=O)N(C)O)c1ccc2c(c1)C(=O)c1ccccc1CO2 +COC(=O)c1cccc(COC(c2ccc(C#N)c(-c3ccccc3C)c2)c2cncn2C)c1 +O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)NCc1ccccc1F +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)Nc1ccccc1CC1c2ccccc2CCN1C +COc1cc(O)c2c(c1)C=CCC(O)C(O)C(=O)C=CC(C)C(C)OC2=O +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)c2cccc(N)c2)CCC3(O)C1C5 +COc1c(C(=O)Nc2ccc(C)cc2C(=O)Nc2ccc(Cl)cc2)sc2ccccc12 +CCOc1ccc(CC(NC(=O)c2sc(C)nc2C)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)cc2)cc1 +COCCNS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 +COc1cc(-c2cncn2C)ccc1Nc1cc2cc(-c3cnn(C)c3)ccc2cn1 +COc1ccc(NC(=O)Nc2ccc(OS(N)(=O)=O)cc2)cc1 +CN(CC=CCOc1ccc(C(=O)c2ccc(Br)cc2)cc1)C1CC1 +O=C(CCCCCNc1c2c(nc3ccccc13)CCCC2)NCCc1c[nH]c2ccccc12 +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Cl)o1)OC(C)(C)C3 +COc1cc(N2CC3CN(CCO)CC(C2)O3)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +NS(=O)(=O)c1ccc(CCN=Cc2cc(Br)ccc2O)cc1 +COc1ncc(-c2ccc3nc(N)nc(-c4ccncc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +O=C(O)c1ccc(-c2ccc(C(Nc3ccccc3F)C(=O)N3CCCC3c3ccccc3F)cc2)cc1 +CCC(Nc1nc(NCc2ccc(C(F)(F)F)nc2)c2ncn(C(C)C)c2n1)C(C)O +C=C(C)n1c(=O)n(Cc2nc3ccccc3n2CCCCCCO)c2ccccc21 +CN1C(=O)N(CC2CC2)CC1C(=O)NCc1ccc(Cl)cc1Cl +CN(C)C(=O)Cn1c(-c2ccccc2)c(C2CCCCC2)c2sc(C(=O)O)cc21 +O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccccc3)c(-c3ccccc3)o2)c1 +CCOC(=O)NC1CCC2C(C1)CC1C(=O)OC(C)C1C2C=Cc1ccc(-c2ccc(OC)cn2)cn1 +CCn1cc(-c2cc3c(-c4cccc(N5CCNC(C)(C)C5)n4)n[nH]c3cn2)cn1 +N#Cc1cccc(Nc2cc(-c3ccccc3)nc3c2C(=O)NCC3)c1 +O=C(O)CCCC=CCC1C2CCC(C2)C1NS(=O)(=O)c1ccc2ccccc2c1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccc(CO)cc1 +Cc1c(C)c2ccc(OCC=CC3=CC(=O)C(C)(C)O3)cc2oc1=O +COC(=O)COc1cc(Br)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +NC(C(=O)N1CCCC1C(=O)NCCc1c[nH]cn1)C(c1ccccc1)c1ccccc1 +CCCCc1cnc(C(CCCC)Cc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 +O=C(NC1CCCCC1)OCC1OC(n2cnc3c(NC4CCOC4)ncnc32)C(O)C1O +C=Cc1ccc(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)c(C)c1 +Cc1ccc2c(c1Br)CCN2C(=O)Nc1ccc(Oc2cccnc2C)nc1 +CC(C)NC(=N)c1cccc(-c2cc3ccc(C(=N)NC(C)C)cc3o2)c1 +NC1CN(c2cc(-c3ccsc3)ncn2)CC1c1cc(F)c(F)cc1Cl 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+COc1ccc2c(c1)OC(=Cc1cc[n+](Cc3cccc(F)c3)cc1)C2=O +Cc1nc2cccnc2n2c(-c3cc(OCCC(C)O)ccc3Cl)nnc12 +CC(NP(=O)(COCCn1cnc2c(N)ncnc21)NC(C)C(=O)OCC(C)(C)C)C(=O)OCC(C)(C)C +CN1C(=O)C(c2ccc(OC(F)F)cc2)(c2cccc(CCCC(F)(F)F)c2)N=C1N +Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C[N+](C)(C)CCCO)cc2)CCO3)cc1 +CN(C)CC(=O)Nc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 +N#Cc1cccc(-c2cc(NC(N)=O)c(C(=O)NC3CCCNC3)s2)c1 +O=C(COc1ccc(Cl)cc1C(=O)c1ccccc1)Nc1ccccc1 +CN(Cc1cccc2ccccc12)C(=O)c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +COc1cc(C)cc(-c2nn(C)cc2-c2cc(NCCCCO)nc(-c3cccnc3)n2)c1 +COc1ccc(C(=O)NCCc2ccccc2)cc1C(=O)NCCc1ccccc1 +Cc1ncsc1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 +O=C(Nc1ccccc1F)NC1CCN(Cc2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)CC1 +O=C(CN1CC(CNCc2ccccc2)=CCC(NC(=O)c2ccc3ccccc3c2)C1=O)NC1CC(=O)OC1O +CC1CCCC1NC(=O)C1CCN(c2nc3cc(Cl)ccc3o2)CC1 +COc1ncc(-c2sc3ncnc(-c4ccncc4)c3c2C)cc1NS(=O)(=O)c1ccc(F)cc1F +CC(C)Cc1cc(=O)nc(Nc2ccc(Cl)c(S(=O)(=O)C(C)C)c2O)[nH]1 +CCC1c2c(C3=CCN(S(C)(=O)=O)CC3)[nH]c3nccc(c23)-c2cc(F)ccc2N1C +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCC(F)(F)C5)ncn4)c3c2)cn1 +CC(C)N1C(=O)C(NC(=O)C(Cc2ccc(F)cc2)NC(=O)OC(C)(C)C)CCc2ccccc21 +CCOc1ccc2ncnc(NCc3ccc4c(c3)OCO4)c2c1 +NCc1cn(S(=O)(=O)c2ccc(N)cc2)c2ccccc12 +O=C(CCCN1CCN(CC=Cc2ccccc2)CC1)NC1c2ccccc2CSc2ccccc21 +CCCn1c(=O)[nH]c2nc(-c3cnn(Cc4ccccc4)c3)[nH]c2c1=O +CS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCNCC(O)c3ccccc3)cc2)cc1OC1CCCCC1 +CN(C)Cc1ccc(-c2[nH]c3cccc4c3c2CNC4=O)cc1 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3cc(F)c(F)cc3[nH]2)o1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccnn3C)n[nH]c2C1(C)C +COc1cc(NC2=CC(=O)c3ncncc3C2=O)cc(OC)c1OC +CCc1nc(N)nc(N)c1C#CCc1cc(-c2ccccc2C(=O)O)ccc1OC +CCCCCc1ccc(NS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +COc1ccc(-c2c(SC)nn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)c2N)cc1 +Cc1cc(=O)oc2c1ccc1oc(C(=O)c3ccccc3)c(-c3ccco3)c12 +COc1cc(O)ccc1C=CC(=O)OCCCc1ccc(O)cc1 +CCCN1C(=O)c2cc(N)ccc2Oc2c(C)cc(C)cc21 +CCC(=O)N1Cc2nc(-c3ccccc3)nn2-c2cc(C)ccc21 +O=C(Nc1ccc(C2CNCCO2)cc1)c1ccn(-c2ccc(Cl)cn2)n1 +CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4cccc(Br)c4)ccc3Sc3ccc(N)cc3)ncnc2n1 +CCC(C)Oc1ccc2c(c1Cl)CCN(Cc1ccc(C(C)NC(C)=O)cc1)C2 +CC(C)C1NC(=O)CC2C=CCCSSCC(NC1=O)C(=O)NCc1cc(OC(F)(F)F)ccc1CC(=O)O2 +CN1CCN(C(=O)c2ccc(-c3ccc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4c3)o2)CC1 +CCC(C(=O)O)n1c(=O)c2ncccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O +NCc1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CN(C=O)C(c2ccccc2)c2ccccc2)CC1 +Cc1cccc(C2CC2COc2cc(NCc3cnn(C)c3)c(=O)n(C)n2)n1 +Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)c1C#CCO +COc1ccc(C2CC3(N(C)C)CCNC2C(c2ccc(OC)cc2)C3)cc1 +Cc1ccc(-c2c(=O)n(CCCCN3CCC(c4c[nH]c5ccccc45)CC3)c(=O)n3ccccc23)cc1 +CC(C)(C)c1ccc(OCC2CN(c3cccc(C#N)c3)C(=O)O2)cc1 +O=C(O)c1[nH]c2cc(Cl)cc(Cl)c2c1CN1CC(=O)N(c2ccc(Cl)cc2)C1=O +CNc1nc(Nc2cc(OC)c(C(=O)N3CC(C)OC(C)C3)cc2Cl)ncc1C(F)(F)F +COc1ccc(-c2cnc(N)c(-c3ccc(C(N)=O)cc3)c2)cc1OC +FC(F)(F)c1ccc2[nH]c(-c3ccc(N4CCC(c5ccccn5)CC4)nc3)nc2c1 +CC(C)(C)c1cc(N2CCC(=O)NC2=O)cc(C(=O)NCc2ccccc2)c1O +Cc1ccc2on(CC3CC4c5ccccc5Oc5ccc(Br)cc5C4O3)c2c1 +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(NS(C)(=O)=O)cc12)C(=O)O +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCN2CCC(F)(F)C2)CC1 +O=C(Nc1cc[nH]c(=O)c1)c1cc(OC(F)(F)F)ccc1Oc1ccccc1 +CN(CCN1CCCCC1)C(=O)N1CCC(c2ccccc2)CC1 +O=C(c1c(F)cccc1-c1ncccn1)N1CC2CC(Oc3ccc(C(F)(F)F)cn3)C1C2 +N=C(N)NCC(=O)NCC1(Nc2ccccc2)CCN(Cc2ccc3ccccc3c2)CC1 +COc1ccc(CN(C)CCCOc2ccc(NC(=O)c3cccc4c(O)c5cccc(C)c5nc34)c(C)c2)cc1OC +NCCc1cn(S(=O)(=O)c2ccc(Cl)c(Cl)c2)c2ccccc12 +CS(=O)(=O)N1CCN(CCC(CS(=O)(=O)c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)N(O)C=O)CC1 +Cc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +CCOc1nc(C)c(Nc2nc(Cl)cn(C(C)C3CC3)c2=O)cc1C +CCN1CCN(c2nc3ccccc3c3c2oc2ccccc23)CC1 +Cc1cccc(-c2[nH]c(CNC(=S)c3ccccc3)nc2-c2ccc3ncnn3c2)n1 +CC(C1CC1)N(Cc1cnc[nH]1)c1cccc(Cl)c1 +COC(C(=O)NC1CCC(OC(=O)C=Cc2ccccc2)CNC1=O)C(O)C(O)C(O)C=CC(C)(C)C +CC(C)c1ccc2nc3ccc(C(=O)N(C)CCCCc4cccnc4)cn3c(=O)c2c1 +CCSc1nnc2c(n1)OC(c1ccco1)N(C(C)=O)c1ccccc1-2 +O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1cc(F)cc(N2CCOCC2)c1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3nc(N)ccc3O)NC(=O)NC1=O)C2 +Nc1nc(Cl)c(C#Cc2ccncc2)c(NC2CC(CO)C(O)C2O)n1 +N#Cc1ccc(COc2ccc3c(=O)cc(N4CCOCC4)oc3c2)cc1 +CCC(COC)N(C)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3C#N)cc2)cc1 +COc1ccc(-n2nc3c(N(C(=O)c4ccccc4)C(=O)c4ccccc4)nc4ccccc4n3c2=O)cc1 +N#Cc1cc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)ccc1Oc1ccnc(NC(=O)C2CC2)c1 +CC1CNC(=O)c2[nH]c3ccc(C(=O)Nc4cccc(C#N)c4)cc3c21 +COc1ccc(OC)c(NC2=CC(=O)c3c(cnc4c3C(=O)CCC4)C2=O)c1 +O=C(O)CCCCCCC(CNS(=O)(=O)c1ccc(Cl)cc1)c1cccnc1 +O=S(=O)(c1cccc(C(F)(F)F)c1)c1cc(F)c2oc3c(c2c1)CNCC3 +CCOP1(=O)N=C(C2=C(O)C(C(C)(C)C)N(CCC(C)(C)C)C2=O)Nc2ccc(OCC(N)=O)cc21 +CCOC(=O)N1CCC(N2CCC(C3(c4ccc(S(=O)(=O)c5ccc6c(c5)OCO6)cc4)OCCO3)CC2)CC1 +COC(=O)c1c(Br)c(OC)c2c(c1-c1c3c(c(OC)c(Br)c1C(=O)OC)OCO3)OCO2 +O=C(O)CC(NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)s1)C(=O)CSCc1ccccc1Cl +N#Cc1nc(NCc2cccc(-c3ccccc3C(F)(F)F)c2)c2ncn(CCCO)c2n1 +CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(N2CC(F)(F)C2)cn1)C(N)=O +CC(=O)NC(C)(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 +CCNc1n[nH]c2c(C)c(NC(=O)NC(C)c3ccccc3)ncc12 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C1CCCN1C(=O)CC +NC(=O)c1ccc(NC2CCCCC2N)cc1Nc1ccccc1Br +Nc1ncc(-c2ccncc2)nc1-c1ccc(C(F)(F)F)nc1 +N#CC1(NC(=O)C2Cc3ccc(cc3)OCC=CCCc3ccccc3C(=O)N2)CC1 +CCCCc1nnc(C(=O)C(NC(=O)Cn2c(-c3ccc(F)cc3)ncc(N)c2=O)C(C)C)o1 +N#Cc1cccc(C(=O)Nc2ccc(C3CNCCO3)cc2F)n1 +COc1ccc(COc2ccc(-c3cc(C=C4CN5CCC4CC5)on3)cc2)cc1 +CCCCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C +O=C(CCCc1ccccc1)OC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nccn5c4)c3c2)CC(C(=O)O)C1 +CN(C)CCN(C)C(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)N1CCCC1C(=O)O)C(CS)Cc1ccccc1 +Nc1nccc(-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)n1 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)CC5)ccn34)c12 +O=C1C2Cc3c([nH]c4ccccc34)C(c3ccc4c(c3)OCO4)N2C(=O)CN1C1CCN(CC2CCCCC2)C1 +NS(=O)(=O)c1ccc(-n2nc(C(F)F)cc2-c2ccc(Cl)cc2)cc1 +Cc1ccccc1-c1ccc2c(ccc3sc4c(c32)NCC(C)NC4=O)n1 +Cn1ncnc1-c1c2c(=O)n(C)c(=O)n(CC3CC3)c2nn1Cc1ccnc2ccc(Cl)cc12 +Cc1cccnc1NCC1CCC(NC(=O)c2cc(C(F)(F)F)ccc2Cl)CC1 +O=C(NNC(=O)C12CC3CC(CC(C3)C1)C2)c1ccncc1 +CC(C)Oc1ccc(-c2nc(-c3ccc4c(CCC(=O)O)c[nH]c4c3)no2)cc1Cl +CN(C)c1nc2ccc(NC(=O)c3c(C(=O)N4CC(F)C4)cnn3C)cn2n1 +Cc1c(C(=O)N2CCN(C(=O)c3ccc(Br)cc3)C(c3ccc(Cl)cc3)C2)cnn1-c1cccc(C#N)c1 +COc1cccc2c(C3=C(c4cn(C)c5cc(I)c(F)cc45)C(=O)NC3=O)coc12 +Cc1cc(-c2nnc3c4c(c(OCc5ccccn5)nn23)CCCC4)no1 +c1ccc(N2CCN(CCCOc3ccc(-c4nc5ccccc5[nH]4)cc3)CC2)nc1 +COc1cccc2c1OC(CN1C3C=C(c4ccc5ccccc5c4)CC1CC3)CO2 +O=c1[nH]c(C2CCC(c3ccccc3)CC2)c(Cc2c(Cl)cccc2Cl)c(=O)[nH]1 +CC(=O)Nc1ccccc1Nc1ccc(C(=O)c2ccccc2C)c(Cl)c1 +COc1ccc(S(=O)(=O)n2ccc3ccnc(-c4ccc([N+](=O)[O-])cc4)c32)cc1 +CCCCC(OP(=O)(O)CCCCc1ccccc1)C(=O)N1CCCC1C(=O)O +O=C(Cc1ccccc1)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12 +O=C(O)CCCOc1cc(Cl)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CCS(=O)(=O)N1CCCCC(=O)N2CCc3cc(ccc32)Nc2ncc(C(F)(F)F)c(n2)NCc2ccccc21 +CCOc1ccccc1-c1cc2[nH]c3ccc(O)cc3c2c2c1C(=O)NC2=O +Cc1cccc(-c2cc(C(=O)NCc3ncccc3C)nc(N)n2)c1 +Cc1ncc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)c1ccc(N2CCCC2)nc1 +Cc1cccc2cc(C=CC(=O)c3ccc(Br)s3)c(Cl)nc12 +O=C(Nc1ccc(N2CCN(C(=O)C3CCC(C(=O)O)CC3)CC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F +COC(=O)CNCCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1 +Cc1ccc2c(c1)nc(C)n2C1CCC(NCC2Cc3ccccc3C2)CC1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)n(-c2ccccc2)n1 +COc1cc(OC)c2c(C)[n+](-c3ccc(C(C)C)cc3C(C)C)c(C)cc2c1 +O=C(O)CCn1cc(Cc2ccc(F)cc2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc21 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)Nc1cnn(CC(F)F)c1 +O=C(Nc1ccn2ccnc2c1)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +CCOC(=O)C1=C(N)N=C2c3c(-c4ccc(Br)cc4)cn(-c4ccc(S(N)(=O)=O)cc4)c3N=CN2N=C1 +COc1cc(OC)c(C2C(c3ccccc3)C(=O)N2c2ccc(S(N)(=O)=O)cc2)cc1OC +CCCC[S+]([O-])c1sc2nc(-c3nccs3)cc(-c3nccs3)c2c1N +COCCn1cc(C2CCN(Cc3cccc(C(=O)O)c3)CC2)c2ccc(F)cc21 +COc1ccc2c(c1)OCCc1sc(NCC3CCC(NS(C)(=O)=O)CC3)nc1-2 +CCN1CC(O)CC1CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +COc1ccc(N2CCN(CCCCn3ncc(=O)n(C)c3=O)CC2)c(C#N)c1 +CCn1ncc(C(C)(C)c2ccccc2)c1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2ccccc2)CC1 +CCCN(C)C(=O)c1cc(N)n2nc(-c3ccc(Br)o3)nc2c1 +O=C(O)CCNc1ncc2c(n1)c(Nc1cccc(Cl)c1)nc1cc(C(=O)O)ccc12 +CC(=O)N1CCN(c2cccc(-c3cc(-c4cnn(C5CC5)c4)c4c(N)ncnn34)c2)C(=O)C1(C)C +O=C(CBr)N(c1ccccc1)S(=O)(=O)c1cc(Cl)sc1Cl +CN1CCN(c2cccc(CCNC(=O)c3cnc(C#N)nc3NCC(C)(C)C)c2)CC1 +CSc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F +O=C(Nc1ccccc1Cl)Nc1cccn(Cc2ccccc2Cl)c1=O +COc1ccc(Cc2nccc3cc(OC)c(OCCF)cc23)cc1Br +CCC(C1CCC(=O)O1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cn1c(=O)c2c(cc(C=Cc3ccc(C#N)cc3)n2C)n(C)c1=O +O=C(NO)C(CCCc1cccc(Oc2ccccc2)c1)P(=O)(O)O +O=c1[nH]nc2[nH]c(CNCCc3cccc(C(F)(F)F)c3)nc3cccc1c32 +N#Cc1ccc(Cc2cc(C(=O)C(=O)Nc3cccnc3)c3ccccn23)cc1 +COc1ccc(-c2nc3n(Cc4ccccc4F)c(C)c(-c4cccc(F)c4)c(=O)n3c2CN(C)CCc2ccccn2)cc1 +O=C(NCCNC(=O)c1cn(-c2ccccc2)nc1C(F)(F)F)c1ccc(-n2cccn2)cc1 +O=C(NCC(O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1)c1c[nH]nc1C1CC1 +O=c1[nH]c(Cc2ccccc2-c2cc[nH]n2)nc2c1cnn2C1CCOCC1 +Oc1ccc(-c2cc(-c3ccoc3)cc(-c3cccc(O)c3)n2)cc1 +COc1ccccc1N1CCN(CCCCCCCn2ncc(Cl)c(N3CCN(CC4COc5ccccc5O4)CC3)c2=O)CC1 +O=S(=O)(Nc1cncc(-c2ccc3ncc(-c4ccccc4)n3c2)c1)c1ccccc1 +[C-]#[N+]c1cnc2c(NCC)nc(Nc3cc(C#N)cc(N4CCC(NCC(C)O)CC4)c3Cl)nn12 +COc1ccc(CNC(C)c2ccc(F)cc2)cc1-c1ccc(C(F)(F)F)cc1 +COCCNc1nc(-c2ccc(C3(O)CCC3)cc2)cc2ncn(C)c(=O)c12 +OCC1C(O)C(O)C(O)CN1CCCCCOCc1cc2ccccc2c2ccccc12 +COc1c(C(=O)NCCN2CCCC2)n(C)c2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21 +CCCOC(=O)N1CCC(N(C(=O)c2ccc(-c3cnco3)cc2)C2CC2)CC1 +O=C(NC1CCN(Cc2ccc(C(F)(F)F)cc2)CC1)c1ccc2ccccc2c1 +CC(C)(C)c1cc(NC(=O)Cc2cccc(Oc3ccc4nccn4n3)c2)no1 +CC(=O)N1CCN(c2cccc(-c3cc(-c4ccnn4CC(F)(F)F)c4c(N)ncnn34)c2)C(=O)C1(C)C +Cc1cccc(Nc2ccccc2C(=O)NCCCCCC(=O)NCCCCCCNc2c3c(nc4cc(Cl)ccc24)CCCC3)c1C +N#Cc1ccc2ncc(C#N)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)cc1NC(=O)CC(C)C +O=C(NCC(c1cccnc1)N1CCN(c2ccc(F)cc2)CC1)c1ccco1 +COc1ccc(CN2CCN(Cc3ccccc3)C(CO)C2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1Cc2ccccc2C1)c1ccc(NS(C)(=O)=O)c(F)c1 +CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl +CC(C)CCN(CCC(C)C)CC(O)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21 +O=C(O)Cc1c2n(c3ccccc13)CC(N(Cc1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1)CC2 +CCCCOC(=O)c1ccc(NC(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1ncn(-c2ccc(Nc3ncc4cccc(-c5nccs5)c4n3)cc2)n1 +CC(C)COP(=O)(CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)OCC(C)C +Cc1ccccc1C(C)(C)CC(O)(Cn1ccc(=O)c2ccccc21)C(F)(F)F +CC(=O)OCC1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C +CCCNC(=O)Nc1cccc(-c2ccc(CC(NC(N)=O)C(=O)O)cc2)c1 +Clc1ccc(-n2cc3c(n2)c(NC2CCCCC2)nc2ccccc23)cc1 +O=C(O)c1ccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2sc3ccccc3c2C2CCC2)cc1 +Cc1ccc(F)c(CNc2ccc(C(=O)Nc3onc(C)c3C)nn2)c1F +Cn1c(=S)c2nc(C3CCCC3)[nH]c2n(C)c1=O +O=c1ccc(OCCCN2CCN(c3nsc4ccccc34)CC2)nn1-c1ccc(Cl)c(Cl)c1 +COc1ccccc1N1CCN(CC2COC3(CCN(C(C)=O)CC3)O2)CC1 +COCC1CCC(C)N1c1cc(NC(C)=O)nc(-n2nc(C)cc2C)n1 +CCN1Cc2ccc(NC(=O)c3ccc(C(=O)N4CCC(C5CCCN5)CC4)c(Nc4ccccc4)c3)cc2C1 +O=C(Nc1ccc(-c2nnc(NCCCCN3CCCCC3)o2)cc1)C1CCCCC1 +CCOC1CN(Cc2ccc(C#Cc3ccc(C(=O)N(C)C(C(=O)NC)C(=O)NO)cc3)cc2F)C1 +CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCCc3c(C)cccc3C)c2)NC(=O)N1 +O=C1c2ccccc2CC1CCC1CCN(Cc2ccccc2)CC1 +CC(C)CC(NC(=O)CNc1cccc(Oc2ccccc2)c1)C(=O)NC1CC(=O)OC1O +CC(C)CCNC(=O)C1CCN(Cc2cccc(NC(=O)c3cccc(C(F)(F)F)n3)c2)CC1 +c1ccc(-c2cc[n+](Cc3cccc(-c4cccc(C[n+]5ccc(-c6ccccc6)cc5)c4)c3)cc2)cc1 +O=C(NC1CCCc2c1[nH]c1ccc(Cl)cc21)c1ccccc1F +Cc1nccc(-n2c(Nc3cccc(O)c3)nc3ccccc32)n1 +Nc1nc(-c2cc(=O)oc3cc(Sc4ncc(C(O)(C(F)(F)F)C(F)(F)F)s4)ccc23)cs1 +OCc1cc(OCC(O)CNC2CCN(c3ncnc4sccc34)CC2)ccc1O +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(Oc4cnccn4)cc3)C2)cc1 +O=C(NCc1ccc(Br)cc1)Nc1ccc(-c2ccnc3[nH]cnc23)cc1 +COCCOC(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +C=C(c1ccccc1)C12CCCC1CC(CCCCCC)=C2CCCC +CCOC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +CCCN1CCN(c2cc(-c3ccc(Sc4ccccc4OC)c(C(F)(F)F)c3)ccn2)CC1 +O=c1cc(-c2ccc(OC3CCN(C4CCC4)CC3)cc2)cn[nH]1 +COc1ccc(C2CC2COc2cc(NCc3ncccc3C)c(=O)n(C)n2)nc1 +C=CC(=O)N1CCCC(Nc2ncnc(N)c2C(=O)c2ccc(Oc3ccccc3)cc2)C1 +CCN(CC)CCCCNc1cc2nc(N)c(-c3c(Cl)cccc3Cl)cc2cn1 +CN1CCC(NC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)CC1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1ccccn1 +O=C(NO)C1(NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CC2CCC(C1)O2 +CN(C)c1ccc(C=C2C(=O)N(Cc3ccccc3)c3ncccc32)cc1 +CC(=O)NC(C(=O)O)C1CCC(=C2SCCCS2)C1 +O=C1COC2(CCN(S(=O)(=O)c3ccc(-c4cccc5cnccc45)cc3)CC2)CN1C1CC1 +CC(C)COc1ccc(-n2cc(C(=O)O)cn2)cc1C#N +COc1ccc(Br)cc1Cn1c(C(=O)NCCCO)cc2cc(C#N)ccc21 +COc1ccccc1N1CCN(CCC(=O)NC2CCc3c(cccc3OC)C2)CC1 +CCC(C)C(N)C(=O)NS(=O)(=O)OCC1OC(c2nc(-c3ccccc3OC)cs2)C(O)C1O +Cc1noc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)n1 +CCOC1CCC(CS)(C(=O)NC(Cc2ccccc2)C(=O)NC2CCCC2)CC1 +CCN1CC(C)(C)Oc2nc(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)Nc4cccc(OC)c4)cc3)c2C1=O +COC1(C(=N)C=C(O)OCc2ccc3ccccc3c2)CCOCC1 +CN(C)C(=O)C(c1ccc(-c2ccc(F)cc2F)cc1)C(N)C(=O)N1CCC(F)C1 +O=C(C=Cc1ccccc1)NC1COC(=O)CCCC(CN2CCOCC2)OC(=O)C(O)C(CC2CCCCC2)NC1=O +c1cc2nc3ccc(N4CCCCC4)cc3[o+]c2cc1N1CCCCC1 +CNc1nc2cc3c(cc2[nH]1)N(Cc1ccc(S(=O)(=O)c2ccccc2)cc1)CCC3 +CC(OC1OCCN(Cc2n[nH]nc2CN2CCC2)C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(=O)NCCOc1ccc(C(=O)N2CCC(N3C(=O)CCc4ccccc43)CC2)cc1 +O=C(O)CCc1cc(Br)c(OCC2CCCCC2)c(Br)c1 +c1cc(COc2ccc(-c3nc4ccccc4[nH]3)cc2)cc(COc2ccc(-c3nc4ccccc4[nH]3)cc2)c1 +COc1ccc(CC(=O)NC(NC(=S)Nc2ccccc2C)C(Cl)(Cl)Cl)cc1OC +CNS(=O)(=O)Nc1cccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1 +CC(=O)c1cccc(-c2cc3nc(N)nc(N)c3cc2C)c1 +COc1cccc(OC)c1C1CCC(=O)N1Cc1cccc(-n2cccn2)c1 +CC(N=C1C=C(O)c2cccnc2C1=O)C(O)c1ccccc1 +CN1CCCC(Nc2ncnc3[nH]cc(-c4cccc(C#N)c4)c23)C1 +CC(C)C(=O)Nc1ccc2nn(-c3ccc(Cl)cc3)nc2c1 +COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)CC2c2ccc(OC(C)C)cc2)cc1 +Cc1ccc(C(C#N)=C(c2ccc(O)cc2)c2ccc(O)cc2)cc1 +N#Cc1ccc(NCC(F)(F)c2ccccn2)[n+]([O-])c1CC(=O)NCc1cc(Cl)ccc1-n1cnnn1 +O=C(C=Cc1ccc(CNCCc2c(-c3cccs3)[nH]c3ccccc23)cc1)NO +CC(C)CC1NC(=O)C2Cc3c([nH]c4ccccc34)CN2C1=O +CCc1ncc(C(CNC(=O)c2c(Cl)cccc2Cl)N2CCC(F)(F)CC2)cn1 +Cc1cccc2nc(N3CCN(Cc4ccc(Br)s4)CC3)c3cccn3c12 +COc1ncc(-c2cc(NC(=O)c3ccnc(C(C)(C)C#N)c3)ccc2C)cc1N1CCOCC1 +COCCN(C)CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(Cc1ccc(Cl)cc1Cl)NC1COc2cnc(Cl)cc21 +C#CCC(C(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)C(C)C)c1cc(Br)ccc1OC +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ccccn2)CC1 +Cc1cc2c(OCC(O)CN3CCC(c4cc5cc(F)ccc5s4)CC3)cccc2[nH]1 +C=CCN1CCC23c4c5ccc(O)c4OC2C(=NNC(=O)c2ccccc2)CCC3(O)C1C5 +Cc1ccc(Nc2ccc(-c3cc(OC(C)C)ccc3F)nc2)c(C(=O)O)c1 +CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(-c3ccc(O)cc3)n2n1 +N#Cc1cccc(NC(=O)Nc2ccc(C3CNCCO3)cc2Cl)c1 +N=C(N)N1CCCC1Cc1nc(-c2ccc(Nc3nc(-c4ccc(F)c(C(F)(F)F)c4)cs3)cc2)no1 +NC(C(=O)N1CCC(F)C1)C1CCC(NC(=O)c2ccccc2C(F)(F)F)CC1 +CCCCCCCCCCCCCCCCCCSCC(COC)COP(=O)([O-])OCC[N+]1(C)CCCCC1 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+CN(CCNc1ccnc2cc(Cl)ccc12)CCN1C(=O)C=C(OCc2ccccc2)C1(O)Cc1ccccc1 +O=C(O)CCNc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 +CC(C)(C)CCN1CCCc2cc(Oc3ccc(C(N)=O)cn3)ccc2C1 +NC(=O)C1(c2ccccc2CCc2nc(Nc3cncnc3)ncc2Cl)CC1 +CN(C)c1nc(NN=Cc2ccc([N+](=O)[O-])o2)nc(N(C)C)n1 +COc1cc(C(F)(F)F)ccc1-c1nccc2cc(S(=O)(=O)Nc3nccs3)ccc12 +O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1cccc2ncccc12 +CN1CCN(c2nc(NCc3ccccc3)c3c(n2)-c2ccccc2CC3)CC1 +CCC(=O)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)CC1CCCCC1 +CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)N1CCC(C(N)=O)CC1 +COc1cc(S(=O)(=O)c2cccc(-n3cccn3)c2)cc2c3c(n(C)c12)CC1CCC3N1 +Cc1ccc(Br)c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)c1 +COCCOC1CCN(c2cc(C)c3nc(-c4c(NCC(O)c5cccc(Cl)c5)cc[nH]c4=O)[nH]c3c2)CC1 +CN(C)C(=O)c1sc2c(c(N3CCC(COCCN4CCCC4)CC3)nn2C)c1-c1ccccc1 +CSc1ncc2cc(-c3ccccc3)c(-c3ccc(CN4CCC(C(=O)Nc5ccncc5)CC4)cc3)nc2n1 +O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccnc(Cl)c1 +COc1ccccc1C=CC(=O)NCCn1c(C)cc2ccccc21 +CNC(=O)CC1COc2cc(Cl)ccc2N1C(=O)c1ccc2c(c1)NC(=O)CO2 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1ccc(N)nc1 +O=C(Nc1ccsc1-c1ccccc1)OC1CN2CCC1CC2 +COC(=O)CN1C(=O)C2(CCN(CC3CCCCCC3)CC2)c2ccccc21 +COc1cc(NC(=O)C=Cc2cccc(C)c2)ccc1-c1cnco1 +COc1ccc2c(OCc3nnc4ccc(-c5cc(C)no5)cn34)ccnc2c1 +O=C(Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)c1ccc(-c2ccccc2N2CCCCC2)cc1 +CC1CN(C(c2cccc(O)c2)c2ccc3c(c2)CN(CC(=O)O)C3)C(C)CN1Cc1ccccc1 +N#Cc1ccc(C(=O)N2CCC3(CC2)Nc2cc(Cl)ccc2-n2cccc23)cc1 +O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCCCSC(CCO)C(=O)O)c1 +O=C(Cn1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2Cl)n1)NCc1ccc(F)cc1 +Cc1ccc2c(-c3nnc(SCCCN4CC5CC5(c5ccc(C(F)(F)F)cc5)C4)n3C)cccc2n1 +CC(C)(Cc1ccc(-c2cccc(-n3cc(C(=O)NC4CC4)c(=O)c4cccnc43)c2)cc1)C(=O)O +CCc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(-c4ccccc4CN(C)C)cc2)CC3)cc1 +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)Nc2cccc(NC(=O)NCC(=O)O)c2)cc1 +COc1cc(C)c2c(Oc3cccc(C(F)(F)F)c3)c(OC)cc(NC(C)CCCN)c2n1 +CC(=O)Nc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1 +Cc1cc(Nc2nc3ccc(C(=O)Nc4c(C)cccc4Cl)cc3s2)ncn1 +CCCCNC(=O)C1CCN(CC(=O)Nc2cc(N)c(C#N)c(OCC)n2)CC1 +CCCCC(CC(CCc1ccc(-c2ccc(C(=O)OC)cc2)cc1)C(=O)NC(C(=O)NC)C(C)(C)C)C(=O)O +Cc1c(I)c(=O)n(C2CCCC2)c2nc(Nc3ccc(N4CCNCC4)cc3)ncc12 +O=C(CCCCCCCCCCCCc1ccc(C(F)(F)F)cc1)Nc1ccc2nc([N+]34CCC(CC3)CC4)ccc2c1 +CCOC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCc1ccccc1Cl +Cc1c(OC2CCN(CC3CCN(C(Cc4ccccc4)C(=O)O)CC3)CC2)ccc(Cl)c1Cl +COc1ccc2c(c1)CCCC2CCCN1CCCC(C)(C)C1 +OCc1cc(N2CCCC2)ccc1-c1nc2c(s1)C(O)CNC2 +CN1CCN(C(CN2CCN(CCCCc3cccc4ccccc34)CC2)c2ccc(Br)cc2)CC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OC4CCOC4)c3)C2)cc1 +c1ccc2c(c1)COC21CCN(CCCCc2cn(-c3nccs3)c3ccccc23)CC1 +CNC(=O)C(NC(=O)C(CC(C)C)C(NS(=O)(=O)CCc1ccncc1)C(=O)NO)C(C)(C)C +CCC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +CN(C)c1ccc(C(O)c2ccc(N(C)C)c3ccccc23)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3cccc(N4CCOC(C)(C)C4)n3)C2)cc1 +CNC1c2cc3c(ccn3S(=O)(=O)c3ccccc3)cc2C1CCO +CC(C)c1cccc(C(C)C)c1NC(=O)NCCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1 +COc1ccc(N(C)c2nc(C)nc3ccc(N(C)C)cc23)cc1 +N#Cc1cc2c(F)c(F)cc(-c3ccc(OCc4cccc(C(=O)N5CCCC5C(=O)O)c4)cc3)c2o1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCc1cccc(I)c1 +N#CC(=C(c1ccccc1)c1ccc(O)cc1)c1ccc(O)cc1 +CCC12CC(C)(O)C(O)(c3ccccc3)CC1C=Cc1cc(O)ccc12 +CCC(NC(N)=O)C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +COc1cc(-c2ccc(Cl)c(C)c2)c(F)cc1-n1c(=O)cnc2cc(S(=O)(=O)Nc3ccon3)ccc21 +N#CCC1(n2cc(-c3c(F)cnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)c3ccc(O)c(F)c3)CC2)C1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)O)c1ccc2c(c1)nc(-c1ccoc1)n2C1CCCCC1 +COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +CC(O)CC(c1ccccc1)c1c(O)oc2ccccc2c1=O +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2C(c2ccccc2)c2cccnc2)c1 +Cc1cccc(-c2nn3c(c2-c2ccnc4ccc(Br)cc24)CCC3)n1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)NC)cc1 +CN1CCC(c2c[nH]c3ccc(NS(=O)(=O)c4cccc5c(Cl)cccc45)cc23)CC1 +COc1cc(N2C(=O)c3ccccc3C2=O)ccc1NC(=O)c1occc1C +Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NC(C)C)cn1 +O=C(Nc1cn2nc(-c3cn(C4CC4)nc3-c3ccc(F)cc3)ccc2n1)c1ccnc(F)c1 +CNC(C)C(=O)NC1C(=O)N(Cc2cccc3c2cc(C#N)n3-c2ccccc2C#N)c2ccccc2SC1(C)C +C#CCN(Cc1ccc2cccc(O)c2n1)C(C#N)CC1CCN(Cc2ccccc2)CC1 +CCN(CC)Cc1cccc2c1-c1nc(N)nc(-c3ccccc3)c1C2=O +CC(C)CC(NC(=O)c1cccs1)C(=O)NC1COCC1=O +CC1C2Cc3cc(N)c(C(N)=O)cc3C1(C)CCN2CC1CC1 +COc1cc(-c2cccc(C#N)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C)c1c(Oc2ccccc2)cc(CCc2ccccc2)[nH]c1=O +CS(=O)(=O)N1CCC(c2nccnc2Oc2ccc(Nc3ccccn3)cc2)CC1 +CN(C)C1CCN(c2ccc(Nc3c(S(C)(=O)=O)cnc4ccc(-c5cc(F)c(O)c(Cl)c5)cc34)cn2)C1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2ccc(NC3CCN(C(=O)CCCN4CCCC4=O)CC3)nc2)c1 +Nc1ncnc(N2CCC(c3nc(-c4ccnc(C(F)(F)F)c4)cn3CCN3CCC3)CC2)c1Br +CSc1c(C2=C(c3cn(C)c4ccccc34)C(=O)NC2=O)c2ccccc2n1C +CS(=O)(=O)Nc1cc(C2C([N+](=O)[O-])C(c3ccccc3Br)CCN2Cc2cccnc2)ccc1O +O=C(Nc1c[nH]nc1C(=O)Nc1ccc(F)cc1)c1ccccc1 +OCC1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)C1 +Cc1noc(C2CCCN(Cc3ccc(-c4nnc5n4-c4cccnc4Nc4ccccc4-5)cc3)C2)n1 +CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3ccc(F)cc3)c2)CC1 +c1ccc2nc(N3CCC(Oc4nccnc4-c4ccncc4)CC3)ccc2c1 +COc1ccc(C(CC(=O)O)Cc2csc(CCCCNc3cc(N4CCSCC4)ccn3)n2)cn1 +O=C(NCc1ccncc1)c1sc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1C(F)(F)F +NC1CCCCC1NS(=O)(=O)c1ccc(-c2ccc(CSc3nc4c(c(=O)[nH]3)CCC4)cc2)cc1 +Nc1nccn2c(C3CCC3)nc(-c3cccc(OCc4ccc(Cl)cc4)c3)c12 +CCC(=O)c1ccc(OCC(O)CN2CCN(c3ccccc3C)CC2)cc1 +COc1cncc(-c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)n1 +N#CC(Cc1ccc(-c2ccc3c(c2)COC3=O)cc1)NC(=O)C1NC2CCC1C2 +CC(NC(=O)c1cncc2cccnc12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1 +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)C(N)Cc3ccncc3)CC2)cc1 +CC1(O)CC(N)(c2ccc(-c3nc4n(c3-c3ccccc3)COc3cccnc3-4)cc2)C1 +NS(=O)(=O)c1ccc(-c2ccc(NC(=O)C3CN4CCC3CC4)cc2)cc1 +CN(CCCCNC(=O)c1cc2ccccc2o1)C1Cc2cccc3[nH]c(=O)n(c23)C1 +COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)C(CO)C2)ccc1Cl +Nc1ccc(-c2ccc(Cl)cc2)n[n+]1CCCC(=O)O +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nc(C)sc5c4)c3c2)CCC1C(N)=O +Cc1c(Cc2ccccc2)nc(SCCCc2ccccc2)[nH]c1=O +NS(=O)(=O)c1ccc(NC(=O)NCCN2CCN(Cc3ccccc3)CC2)cc1 +CC1(C(=O)N2CCOCC2)COC(c2nc(-c3ccc(F)cc3)c(-c3ccnc(NCC4CC4)n3)[nH]2)OC1 +CC(C)c1cccc(C(C)C)c1NC(=O)NC1=NN(CCCCCCCCCCCO)NN1 +CC(NCC(O)C(Cc1ccccc1)NC(=O)c1ccc(N(C)c2ccncc2)cc1)c1ccccc1 +O=C(c1cncc2ccccc12)N1C2CCC1C(Nc1cnc(C(F)(F)F)cn1)C2 +OC1CCN(Cc2ccc(F)cc2)CC1N1CCC2(CCc3ccccc32)CC1 +CCCN(c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1)S(C)(=O)=O +O=C(Cc1ccc(-c2ccccc2)cc1)NC1CCN(Cc2ccc3c(c2)OCO3)CC1 +CNC(=O)C(NC(=O)c1ccc(-c2cccc(CNC(=O)c3occc3C)c2)o1)C1CCCCC1 +c1nc(CC2CCN(CCCOc3ccc(N4CCNCC4)cc3)CC2)c[nH]1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4ccccc4C#N)CC3)CN(C)C1C2 +Cn1cnc(C(=O)N(Cc2cccc(Cl)c2)C2CCC(N)CC2)c1 +COc1cc(C=C2SC(=S)NC2=O)ccc1OCc1ccccc1 +COc1cc(CCNCc2cccc3ccoc23)c(OC)cc1Br +NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4cccs4)nc3)c2)c1 +OC1CCCN(Cc2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nc2)C1 +c1cc(-c2cnn3nc(N4CCOCC4)ccc23)nc(NC2CC2)n1 +CS(=O)(=O)NCC1CC2CCCCC2N1C(=O)CC(N)Cc1cc(F)c(F)cc1F +CCc1nc(N)nc(N)c1-c1ccc2c(c1)N(CCNC(C)=O)C(=O)C(C)(C(F)(F)F)O2 +c1ccc(Nc2ccc(Oc3ncccc3-c3ccsc3)cc2)nc1 +CCN(CC)CCCOc1ccccc2c(C=C3C(=O)Nc4ccc(F)cc43)cc(C)c1-2 +COc1cc(C2CCNCC2)ccc1Nc1nc(Cc2cccc(Cl)c2Cl)n2cnnc2c1C(N)=O +O=C(NO)C1CCS(=O)(=O)N1c1ccc(-c2ccccc2)cc1 +COc1cnn(C)c(=O)c1-c1ccc(CC(NC(=O)N(c2ccccc2)C(C)C)C(=O)O)cc1 +CCCOc1ccc(-c2csc(C)n2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 +O=C(O)C(Cc1ccc(N2CCN(c3cnccn3)CC2)cc1)NC(=O)C1CCCN1S(=O)(=O)c1ccccc1 +CCCCC(C=O)NC(=O)OC(C)(C)Cc1ccc(OC)cc1 +CCCCC(=O)N(Cc1ccc2ccccc2c1)c1cc(-c2nnn[nH]2)ccc1F +O=C(c1cccc(F)c1-c1ncccn1)N1CCC2CN(c3cc(C(F)(F)F)ccn3)C2C1 +NC(=O)c1cn2c(n1)-c1cc(C#CC(O)(CF)CF)c(F)cc1OCC2 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cccc(C(C)(C)C)c4)c3)c2cc1OC +CCCC(=O)NC(c1ccccc1Cl)c1ccc2cccnc2c1O +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(Cl)s1 +Cc1cc(C2CCN(C)CC2)cc2[nH]c(-c3c(NCCn4cc(Cl)cn4)cc[nH]c3=O)nc12 +COc1cc(C(=O)NCc2cccc(-c3ccccc3)c2)ccc1-c1cn[nH]c1 +CCOC(=O)CC1(c2ccccc2)C(=O)Nc2ccc(-c3c(C)noc3C)cc21 +Cc1cccc(C(CO)NC(=O)c2ccc(-c3cc(-c4cn(C)nc4C)cnc3N)cc2F)c1 +NC(=O)N1CCCc2c1ncc(-c1cncc(C3(O)CCOCC3)c1)c2F +O=C(Nc1ccc(N2CCOCC2)cc1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 +Cc1c(C(F)F)nn(-c2ccc(S(C)(=O)=O)cn2)c1-c1ccccc1 +CN1CCC(c2c(O)cc(O)c3c(=O)cc(SC(C)(C)C)oc23)C(O)C1 +CCCc1c(OCCCOc2ccc3c(c2)CCC3CC(=O)O)ccc2c1ccn2C +CC(=NOCC#N)c1ccc(Sc2cc(F)cc(C3CCOCC3)c2)cc1 +O=C(Nc1ccc(OCC(F)(F)C(F)F)c(C(F)(F)F)c1)c1ccccc1O +N#Cc1cnn2c(Nc3ccc4c(c3)CCC(=O)N4)cc(N3CCCC3CO)nc12 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NCC1COC1 +CN1CCN(Cc2ccc(C(=O)NN(CCC3CCCC3)c3nc(C#N)ncc3Br)cc2)CC1 +CCN(Cc1cc([N+](=O)[O-])cc2nc(O)c(O)nc12)CP(=O)(O)O +Cc1ccc2c3c(nn2c1)CCC(NC(=O)c1c(Cl)cc(-n2cnc(C)n2)cc1Cl)(c1cccc(F)c1)C3 +Cc1ccc(-n2c(C)nnc2SCC(=O)Nc2ccccc2C#N)cc1 +O=C(Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)cc1)c1c(F)cccc1F +CN1CCN(CCCNC(=O)c2c(O)c3ncc(Cc4ccc(F)cc4)cc3[nH]c2=O)CC1 +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2COc2ccccn2)o1 +O=C(NC1(C(F)(F)F)CCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1 +Cc1nc(N2CCC(N3CCCC3C)C2)ccc1NC(=O)c1cccc2ccccc12 +Cc1cc(N2CC3CN(C(=O)c4ccccc4-n4nccn4)CC3C2)nc(C)n1 +CN(CCO)c1ccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncs1 +N=C(N)c1ccc2[nH]c(-c3cc(C(CC(=O)O)C(=O)O)cc(-c4cccc(CN)c4)c3O)nc2c1 +CC(C)NCC1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 +CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(N)Cc2ccc(F)cc2)C(CCN(C)C)C1=O +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)cc(C(=O)O)c1 +FC(F)(F)c1cccc(Nc2ncnc3ccc(-c4cncs4)cc23)c1 +C=CCN(C)CCCCCCOc1ccc2c(-c3ccc(Br)cc3)csc2c1 +Cc1ccc(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1-c1[nH]c(C2CC2)nc1Cl +O=C(Nc1ncccn1)C1=C(O)CCn2c1nc1ccccc12 +CCOC(=O)C1C2NC(CC(=O)O)C(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C21 +Cc1nc(C2CC3CSC(N)=NC3(c3ccc(F)cc3F)CO2)co1 +Cc1nnc2c(NC3CCN(S(=O)(=O)C4CCNC4)CC3)cc(N(C)Cc3ccccc3)nn12 +O=S1(=O)NCCCNc2nc(ncc2Br)Nc2cccc1c2 +CN1CCN(C(=O)NC23CC4CC(CC(C4)C2)C3)CC1 +O=C(Cc1ccc2cccnc2c1)Nc1cncc(C(=O)c2cn(C(CO)CO)c3ncncc23)c1 +CC1(c2ccc(OCCN3CCCC3)cc2)c2ccc(O)cc2CCN1c1ccc(Cl)cc1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(C(F)(F)F)cc2F)c1 +COc1ccc(CCN2C=CC=C3C2=Nc2ccccc2N(C)S3(=O)=O)cc1 +O=c1ccc2ncc(F)c3c2n1CC3(O)CN1CCC(NCc2cc3c(cn2)OCCO3)CC1 +CNC(=O)Cn1c(=O)n(C2CCN(C3CCC4CCCCC4C3)CC2)c2ccccc21 +COCCN1CCCC(c2cc3c(-c4cc(F)ccc4OC)ccnc3[nH]2)C1 +NC1CC1NC(=O)c1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +Cc1cccc(N2CCN(CCCNC(=O)c3cc(-c4ccc(Cl)cc4)[nH]c3C)CC2)c1C +CCCCCCCCCCCCCCN(C)S(=O)(=O)NC(=O)Nc1c(C(C)C)cccc1C(C)C +Cn1c(=O)[nH]c2nc(-c3ccccc3)n(C)c2c1=O +COc1cc(Cc2c(C)nc(N)nc2N)cc(OC)c1OC +COc1ccc(Oc2c(-c3ccc(S(C)(=O)=O)cc3)oc(C)cc2=O)c(Cl)c1 +CC(C)N1CCN(c2ccc(C3c4ccc(O)cc4CCN3c3cccc(O)c3)cc2)CC1 +Cc1ccncc1NC(=O)N1CCc2nc(-c3ccc(O)nc3)nc(OC(C)C)c2C1 +COc1ccc2c(c1)[nH]c1c3ccncc3cc(CN(C)C)c21 +COCC(=O)Nc1cccc(NC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Br)c(C)nc34)c2Cl)c1 +COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccnc(NCCO)c2c(=O)n1Cc1ccnc(C)c1 +CC1CCC(CC(CC(=O)N2CCOCC2)C(=O)NC2(C#N)CCN(C3CCCCC3)C2)CC1 +COc1ccc(CN2C=NC3CN(C(=O)C(c4ccccc4)c4ccccc4)C(C(=O)O)CC32)cc1C +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(Cl)c[nH]c4c3)CC1)C2 +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3cc(Cl)ncn3)sc2c1 +O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3CO)s2)s1 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1cccc(C(F)(F)F)c1C)O2)C(C)=CC(C)(C)N3 +COc1ccc2c(c1)C(=Cc1cnc[nH]1)C(=O)N2 +CC1(C)CCC(C)(C)c2cc3c(cc21)CCc1c(-c2ccc(C(=O)O)cc2)nn(Cc2cccnc2)c1-3 +Cn1cncc1C(O)C1=Cc2cccnc2C(N2CCN(C(=O)NCc3ccccc3)CC2)c2ccc(Cl)cc21 +CCc1c(CN2CCCc3ccccc32)nc(SCC(=O)c2ccc(OC)cc2)[nH]c1=O +Cc1cc2n[nH]c(=O)n2c2cc(-c3ccc(CO)cc3)ccc12 +c1cc2c3cnc(Nc4ccc(N5CCC(N6CCOCC6)CC5)nn4)nc3n(C3CCCC3)c2cn1 +O=C1CC(NC(=O)C2CNCC3CCCCC(NC(=O)c4nccc5ccccc45)C(=O)N32)C(O)O1 +CN1CCN(c2ccc(-c3ccnc(Nc4ccc5ncsc5c4)n3)cc2)CC1 +Cc1c(NC(c2nnc(-c3ccc(C#N)cc3)o2)C(C)O)ccc(C#N)c1Cl +CCC1CCCC(NC(=O)C=Cc2cc(Cl)ccc2-n2cnnn2)c2nc(c[nH]2)-c2ccc(NC(=O)OC)cc2NC1=O +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCC(c5ncc[nH]5)CC4)c23)c1 +N#Cc1ccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)cc1 +CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccccc3)C2=O)c(F)c1 +Cc1ccc(NC(=S)N2N=C(c3ccccc3O)CC2c2ccccc2O)cc1 +NC1=NC(c2cccc(F)c2)(c2cccc(NC(=O)c3ncc(Cl)cc3Cl)c2)CS1 +CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)S(=O)(=O)c1cccc(N)c1 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(CN(C)CC(=O)O)cc2C)ncn1 +O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccc(F)c(Cl)c1 +O=C(CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21)NCCO +O=C(C=Cc1ccc2c(c1)CN(C(=O)C1CC1)C2)NO +O=C(NCc1ccc(F)cc1)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCC2=O)c1=O +CC(C)C1NC(=O)C(Cc2cccc(Cl)c2)NCCOc2ccccc2CCCNC(=O)C(CNC(N)=NC#N)NC1=O +NC(=O)c1ccccc1NC(=O)Nc1ccc(Cl)c(Cl)c1 +Cc1cc(N2CCN(C)CC2)nc2ccc(NC(=S)N3CCN(c4ccc(Cl)cc4)CC3)cc12 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCC2CCC3(CCC3)CC2)cc1F +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)Nc2ccc3c(c2)OCO3)C(=O)O)cc1 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1 +CC(=O)NC(CC(C)N1CCC(n2c(C)nnc2C(C)C)CC1)c1ccccc1 +Cc1c(C(=O)Nc2ccc(O)cc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CNC(=O)c1cccc(-c2[nH]nc3cc(C)nc(OC4CCOCC4)c23)c1 +CCOC(=O)C1=C(Nc2ccc3c(c2)c2ccccc2n3CC)SCC1=O +CCCCOc1ccc(C(=O)Oc2ccccc2-c2nc3cc(C)ccn3c2NC(C)(C)CC(C)(C)C)cc1 +N#Cc1ccc2nc(NCCC(F)(F)F)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2c1 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+O=C(O)c1ccc(CN2C3CCC2CC(Nc2ccc(Cc4ccncc4)cc2)C3)cc1 +Cc1cccc(-n2nc(C(C)(C)C)cc2C(=NO)C(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)c1 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OCCOCCOCCN(CCO)CCO)cc2)C1O +CCCCCCN1CC2C(C1)C2(C)c1cccc(NS(=O)(=O)c2cccnc2)c1 +Fc1ccc(-c2cc(-c3cccc(Cl)c3)[nH]c2-c2ccncc2)cc1 +CC(F)(F)c1cc(NC(=O)Nc2cc(F)cc(Oc3cc(NC(=O)C4CC4)ncn3)c2)ccc1Cl +Cc1cc(C)c(NC(=O)c2ccc3nc(NC(=O)C4CC4)sc3c2)c(C)c1 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1 +CC(C)C(NC(=O)C(S)C(C)c1ccccc1)C(=O)N1CCCCC1C(=O)O +COCCN(C)C(=O)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +Fc1ccc(-n2cc(CCCCN3CCC4(CC3)OCc3cccc(F)c34)c3ccccc32)cc1 +COc1ccc(-n2c(C3CC(F)(F)C3)nc3c(NC(C4CC4)C4CC4)nc(C)nc32)cc1 +COc1cc2ncccc2cc1NC(=O)c1csc2cnc(N(C)C(C)C)nc12 +O=C1C(=NO)c2cc(Cl)ccc2N1Cc1cc(F)cc2c1OCOC2 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC(C)(C)CN1CCOCC1 +Cc1ccc(CC(CNC(=O)Cc2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C +CN(C)C(=O)C(c1ccc(-c2ccc(F)cc2)cc1)C(N)C(=O)N1CCCC1 +O=C(Nc1cc(Nc2ccc3c(c2)OCc2ccc(C(=O)N4CCOCC4)cc2C3=O)ccc1F)c1cccs1 +Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc3c(c2)OCO3)c1Cl +C[n+]1c2ccccc2nc2ccc(NC3CCCCC3N)cc21 +CN(CCC(=O)O)C(=O)C1CCCN(C(=O)CCC2CCNCC2)C1 +O=c1cc(-c2ccccc2)oc2cc(OCCCCCCN3CCC(O)CC3)ccc12 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3ccc(C4CC4)n3)c2)c2cnc(N)nc21 +O=C(O)c1n[nH]c2cc(F)c(-c3ccc(C4CCOCC4)cc3)cc12 +CCN(CC#N)C(=O)c1ccc(-c2nc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)cs2)cc1 +CCCCCCCCCCC=C(NC(=O)C1CC1(C)C)C(=O)O +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3ccccc3N3CCN(C)CC3)c3ccccc32)CC1 +CNC(C)C(=O)NC(C(=O)NC1CCCN(CCc2ccccc2OC)C1)C(C)(C)C +CS(=O)(=O)c1ncc(C(=O)Nc2ccc(CCN3CCOCC3)cc2C2=CCCCC2)[nH]1 +COC(=O)c1ccc2c(c1)c1c(n2CCCN2CC(C)OC(C)C2)CCCC1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)c3ccc4ncccc4c3)CC2)C1 +Cc1ccc(C2(O)C(=O)Nc3ccc(-c4c(C)noc4C)cc32)cc1 +OCCCNc1nccc(-c2c(-c3ccc(F)cc3)nn3cc(C(F)(F)F)ccc23)n1 +Cc1cn(C2CC(O)C(CO)(N=[N+]=[N-])S2)c(=O)[nH]c1=O +CCOC(=O)C(C)=CC(C(C)C)N(C)C(=O)C(NC(=O)C(NC)C(C)(C)c1cccc(C)c1)C(C)(C)C 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+FC(F)(F)Oc1cccc(-n2nnc3ccc(NCC4CC5(CCNCC5)C4)nc32)c1 +CN1CCC(Nc2nc(NN=Cc3ccc(Cl)cc3)nc3ccccc23)CC1 +O=C(NC(Cc1c[nH]c2ccc(O)cc12)c1cscn1)c1ccc2c(c1)nc(-c1ccco1)n2C1CCCCC1 +O=C(C=Cc1cn(C(C=Cc2ccccc2)Cc2ccc3ccccc3c2)nn1)NO +CCCc1nc2c(C)cc(NC(=O)c3ccc(C)cc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCNC(=O)C1OC(n2cnc3c(Nc4ccc(OCC(=O)Nc5ccc(N6CCOCC6)cc5)cc4)ncnc32)C(O)C1O +CCCOc1cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc(N(O)C(=O)NCC)c1OCCC +O=C(NC1CC1)c1ccc(-c2nc3cccnc3n2C2CCCC2)cc1 +Cc1ccc(-c2nc(C)c(Cl)c(OCCCN3CCCCC3)n2)cc1 +CCN(Cc1ccccc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +COc1cccc(N(C)C(=N)Nc2cc(SC)ccc2Cl)c1 +COc1cc(CC(=O)NCC(COC(=O)C(C)(C)C)Cc2ccccc2)ccc1O +CCOC(=O)C(Cc1ccc(C(=O)NCc2ccccc2C(F)(F)F)cc1)c1ccccc1 +O=C(O)Cc1nn(Cc2nc3c(ccc4ccccc43)s2)c(=O)c2ccc(Cl)cc12 +CN1C(=O)C(NC(=O)C(Cc2ccc(Cl)c(Cl)c2)c2ccncc2)N=C(c2ccccc2)c2ccccc21 +CC1NC(C(=O)N(CC#N)C2CC2)CC1C(=O)N(C)C +CC(C)=CCc1cc(C(=O)Nc2cc3ccc(OC4CCN(C)CC4)c(C)c3oc2=O)ccc1O +Cc1ncc(CO)c(CNc2ccc(OCCCCCCC(=O)NO)cc2F)c1O +O=C(Nc1ccc(OC(F)(F)F)c(F)c1)c1cccc(-c2cncnc2)c1 +CN1CCC(NC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cccnc43)CC2)CC1 +O=C(Cc1ccccc1)Nc1cc2cc[nH]c(=O)c2cc1Cl +O=C(NCc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1cnc2[nH]ncc2c1 +COc1ccc2c(nc(Nc3c(C)cccc3Cl)c3cnc(C=O)n32)c1OC +CC(C#N)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +C=CCNC(=O)c1ccc2c(c1)N=C(c1ccc(F)cc1)N(CCCC)C2 +Nc1ccccc1NC(=O)c1ccc(N2CCN3CCCCC3C2)nc1 +O=C(NC1CC1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 +COc1ccccc1CC(=O)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1 +CCCOCC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(C(F)(F)F)cc1)C2 +CN(C)c1ccc(-c2nc3c(c(Nc4ccc(CC(=O)O)cc4)n2)SCCC3)cn1 +OC1(c2ccc(Cl)c(Cl)c2)CC2CCC(C1)N2Cc1csc2ccccc12 +CC1CN(Cc2c[nH]nc2-c2nc(C#N)c[nH]2)CCN1c1ccc(C(F)(F)F)cn1 +CC(CCc1ncc[nH]1)C1CCC2(C)C3=C(CCC12C)C1(C)CCC(O)C(C)(C)C1CC3 +Cc1ccc(C(C)(C)C)c(SC2=C(O)OC(CCc3ccccc3)(C(C)C)CC2=O)c1 +O=C(NCc1nccs1)c1ccc2[nH]c(-c3ccc(C(=O)c4ccccc4C(F)(F)F)cc3)nc2c1 +Cc1c(Cc2ccccc2)c(=O)oc2cc(OC(=O)N(C)C)c([N+](=O)[O-])cc12 +Cc1nn(-c2ccc(Cl)cc2)c2c1c(=O)oc1ccccc12 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)NCc2ccccc2)c1=O)C(=O)C(F)(F)F +Cc1noc(C)c1Cn1cc(NC(=O)c2cccc3c2OCO3)cn1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2ccc(CN3CCCC3)cc2)c1 +CCCOc1c(OC)ccc2cc(C(=O)NC3CCCCC3)c(=O)oc12 +COCC(Nc1ncnc2c(C(N)=O)cccc12)c1ccccc1 +O=S(=O)(Nc1ccc(Cl)cc1)c1ccc2c(c1)CNC(CF)C2 +CN1Cc2c(-c3ccc(CC(=O)O)cc3)[nH]c3nccc(c23)-c2cc(F)ccc21 +Cc1cccc(-c2cc(Nc3ccncc3)c3ccccc3n2)n1 +Nc1cnc(-c2cc(Nc3cnc4ccccc4c3)nc(N3CCOCC3)n2)cn1 +Cc1nc(SCC(=O)C2(OC(=O)c3ccco3)CCC3C4CCC5=CC(=O)CCC5(C)C4C(O)CC32C)sc1C +Cc1cccc(Cl)c1C(=O)NC(Cc1ccc(-c2c(C(F)(F)F)n(C)c(=O)n(C)c2=O)cc1)C(=O)O +CC1COCCN1Cc1ccc(Nc2nccc(-c3cc(C#N)c(N4CCC(F)C4)c(C#N)n3)n2)cn1 +CN1CCN(Cc2ccc3c(c2)Cc2c(-c4ccc(-c5ccc(O)cc5)cc4)n[nH]c2-3)CC1 +Cc1cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)cc(C)c1OCCCNCCO +CCc1cc2c(cc1-c1cnoc1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +C=C=CC1(O)CCC2C3CCC4=CC(=NO)CCC4C3CCC21C +Cc1ccccc1-c1nc(C)c2c(C)nc3c(OCC(F)(F)F)cc(F)cc3n12 +CCN(CC)C1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +CCSc1nnc2c(n1)OC(c1ccc(OC)cc1OC)N(C(C)=O)c1ccccc1-2 +CCn1nc(-c2cccc(C#N)c2)cc1C(=O)Nc1ccc(C2CNCCO2)cc1 +CCn1cc2c(n1)N=C(NC(=O)Nc1ccc(C)cc1)N1NC(c3ccco3)=NC21 +O=C(O)C1CCCCC1C(=O)Nc1cc(Cl)cc(Cl)c1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(C)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1ccc2c(c1)nc(N1CCNCC1)n2Cc1ccccc1 +COc1cc2nc(N3CCN(C(=O)c4ccccc4)CC3)nc(N)c2cc1OC +CS(=O)(=O)CCNC1CCC(Nc2cc(-c3ccc(F)c(NCC4CCOCC4)n3)c(Cl)cn2)CC1 +CCc1nc(N)ccc1C#Cc1c(-c2ccc(C(=O)N3CCCC3)c(F)c2)ccnc1C +Cn1nc(C(N)=O)c2c1-c1nc(NCc3cccnc3)ncc1CC2 +COc1cc(O)c(CC=C(C)C)c2oc(-c3ccc(O)cc3)c(O)c(=O)c12 +COc1cccc2c(=O)n3c(nc12)-c1[nH]c2ccccc2c1CC3 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(N4CCN(C(=O)C5CC5(F)F)CC4)nc23)N1 +COc1ccc(NC(=O)C(=O)c2c[nH]c3cc(C#N)ccc23)cc1 +COc1cc(C2=NN(C(=O)c3ccc(F)cc3)C(c3ccc4c(c3)OCO4)C2)cc(OC)c1OC +COc1ccc(-n2nc(C#N)c3ncn(-c4ccc(-c5ccccc5CN5CCCC5)cc4)c(=O)c32)cc1 +O=C(c1cccc(F)c1-n1nccn1)N1CCC2CN(c3nc4cc(Cl)ccc4o3)C2C1 +CCc1ccccc1-c1cc(OC)c2c(n1)CCCC2N(CC)c1cccc2ccccc12 +CC1CN(c2cc(-c3n[nH]c4ccc(-c5ccc(C#N)cc5)cc34)ncn2)CC(C)O1 +Cc1oncc1CN(C(=O)CCC(C1CCCCC1)N1Cc2cc(Oc3ccccc3)ccc2N=C1N)C1CCCCC1 +O=C(O)c1ccc(-c2ccc3c(c2)CC(NCC(O)c2ccc(C(F)(F)F)cc2)CC3)cc1 +O=C(O)CC(c1ccc(Cl)c(Cl)c1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)CC1CCCC1 +N=C(N)NC(=O)c1ccc(C2CCN(C(=O)c3ccccc3Cl)CC2)c(C(F)(F)F)c1 +CC(C)(C)NC(=O)C1CCC2C3CNC4=CC(=O)C5CC5C4(C)C3CCC12C +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1ccccc1OCc1nonc1C#N +O=C(NCc1cccnc1)c1ccc(Br)c(S(=O)(=O)N2CCCCC2)c1 +O=C(NCCNc1ccnc2cc(Cl)ccc12)Nc1ccc(F)cc1 +CCC(CN1CCOCC1)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COc1cccc(Oc2c(NCCOc3ncccn3)ncnc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1 +CC(=O)Nc1ccc2ccn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 +O=C1c2cnn(C3CCCCCC3)c2CCCN1C1C2CC3CC1CC(O)(C3)C2 +O=C(Nc1cc[nH]c(=O)c1)c1ccc(C(F)(F)F)cc1Oc1ccc(F)cc1F +O=C(O)CCC(=O)Nc1cc(Cl)c(-c2cccc3c(Br)c(O)ccc23)c(Cl)c1 +O=S(=O)(c1ccccc1)c1cn(C2CCN(Cc3ccccc3)C2)c2ccccc12 +Cc1n[nH]c(=O)cc1-c1ccc(OCCCN2CCCCC2)cc1 +O=C1NCCCN1CC1CNCCOC1c1ccc(Cl)c(F)c1 +O=C(O)CCCN1CC(c2nnn[nH]2)Oc2c(NC(=O)c3ccc(OCCCCc4ccccc4)cc3)cccc21 +O=C1NCCc2[nH]c(-c3ccnc(-c4cnc5ccccc5c4)c3)cc21 +CN1CCC(NC(=O)Nc2cccc3[nH]ncc23)c2ccccc21 +CNc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 +CCCc1ccc(Nc2ncnn3cc(C(=O)OC)c(C)c23)cc1O +COc1ccccc1N1CCN(C(=O)c2cc(-c3ccc(C#N)cc3)n[nH]2)CC1 +CCCCCCOc1cc2c(cc1OC)-c1c(OC)c(OC)cc3c1C(C2)N(C)CC3 +C=CCC1Oc2ccc(CO)c(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +OC(COc1cccc2ncccc12)CN1CCN(C2c3ccccc3C3C(c4ccccc42)C3(Cl)Cl)CC1 +O=C(OC1CC(n2cc(F)c(=O)[nH]c2=O)OC1CO)c1cccnc1 +COc1cc(-c2nnc3n2CCCC3(CO)Cc2ccc(F)c(F)c2)ccc1-c1cnc(C)o1 +COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(C(C)(C)C)cc1C(=O)NC1CC1 +N#CCNC(=O)C1(NC(c2ccc(-c3ccc(N4CCNCC4)cc3)cc2)C(F)(F)F)CCCCC1 +COc1cc(-c2c(C#Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)ccc1C(=O)O +O=c1[nH]c(=O)n(C2CC(O)C(COP(=O)(O)O)O2)cc1Br +O=C(Nc1ccc(N2CCCCC2)cc1)C1=C(O)C(CCc2ccccc2)NC1=O +Cn1cc(C2=C(c3nnc4ccccn34)C(=O)NC2=O)c2ccc(Br)cc21 +Cn1cc(-c2cnc3ccc(NC(=O)NCCCC(C)(C)c4ccccc4)nc3n2)cn1 +CCN1CCN(c2cc(C)c3cc(NC(=O)C=Cc4ccc(OC(C)C)cc4)ccc3n2)CC1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(C(=O)NO)c1ccc(F)cc1 +CN(C)c1ccc(C=Cc2cnc(OCCO)c(Br)c2)cc1 +CC(=O)Nc1nc(C)c(C(=O)Nc2c(C)cc(C)cc2C)s1 +CCc1cc2c(cc1N1CCC(N3CCC(O)CC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +O=c1[nH]nc(CCc2ccc(C(F)(F)F)c(F)c2)cc1O +CC1CCC(C)N1Cc1cccc2c1-c1nc(N)nc(-c3ccccc3)c1C2=O +Cc1noc2cc(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc43)ccc12 +O=C(O)c1cccc2[nH]c(-c3c(F)c(F)c(-c4ccc(OCc5ccccc5)cc4)c(F)c3F)nc12 +COC1=CC(=O)CC(C)C12Oc1c(Cl)c(OC)cc(OCc3ccccc3)c1C2=O +NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(NC(=O)c3c(F)c(F)c(F)c(F)c3F)cc2)s1 +COc1cc(OCc2cccc(-c3ncc(Cl)cc3Cl)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Cc1nc2c(N3CCOCC3)nccn2c1-c1ccc(N2CCCC2)nc1 +CCCC=CCCCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +O=C1C=CC2(C=C1)CCC1(CC(O)CC3(CCC4(C=CC(=O)C=C4)O3)O1)O2 +Cc1nn(C)c2nnc(Nc3ccc(S(=O)(=O)N4CCN(C)CC4)cc3)nc12 +O=C(NCC#Cc1ccc2ncccc2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +CN(C(=O)Cc1ccc(Cl)c(Cl)c1)C(CN1CCCC1)c1cccc(OCC(=O)O)c1 +Nc1ncnc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)c1C=NOC1CCCCC1 +COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 +COc1cc(Nc2ncc3c(C)nc(-c4ccc(F)cc4)n3n2)cc(OC)c1OC +CCC(C)C=Cc1cc(C(=O)OC)cc2ccc(C(=N)N)cc12 +FC1(COc2cccc3ccc(-c4nnc5ccc(-c6ccccc6)cn45)nc23)CCNCC1 +CC(C)CC(NC(=O)C(Cc1ccccc1)N1CN(C(=O)CNC(=O)C(N)Cc2ccc(O)cc2)CC1=O)C(N)=O +O=C(NCc1ccc(Br)cc1)Nc1ccc2[nH]ncc2c1 +O=S(=O)(c1ccccc1)c1cn(C2CCCNC2)c2ncccc12 +Nc1ncnc2c1ncn2C1OC(CSCCCNC(=O)Nc2ccccc2)C(O)C1O +O=C1c2ccccc2S(=O)(=O)N1COc1nc2ccccn2c(=O)c1Cl +Cc1c(C(=O)NC2(C#N)CCOCC2)nn(-c2ccccc2F)c1-c1ccccc1 +COc1ccccc1N1CCN(CCCN2C(=O)CC(c3ccc([N+](=O)[O-])cc3)CC2=O)CC1 +Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cccc(Cl)c2)n1 +CC(C)Oc1cc(NC(=N)c2ccccn2)ccc1-c1ccc(NC(=N)c2ccccn2)cc1OC(C)C +CC(=O)Nc1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Br)c(C)nc34)c2Cl)cc1 +Cc1onc(-c2ccc(Cl)cc2)c1C(=O)N(C)c1ccc(Cl)cc1 +COCC(NC(=O)c1cc(C)on1)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1 +CC(=O)NCC(C)(C)c1ccc(C#Cc2cnc(NC3CCC3)nc2)cc1 +O=C(O)COCC1CCC(COC(=O)N(c2ccccc2)c2ccccn2)CC1 +COCCN1CCc2[nH]c(-c3ccnc(NC4CCOCC4)n3)cc2C1=O +Cc1cc(C(=O)Nc2ccc(N3CCOCC3=O)cc2)n(-c2ccc3cc(Cl)ccc3c2)n1 +CSc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1cccs1 +CC(=O)N1CCN(C(=O)C=Cc2ccc(Sc3ccc4c(c3)OCC(CO)O4)c(Cl)c2)CC1 +CCC(C)COc1ccc(C(CC(=O)O)c2ccccc2)cc1 +Fc1ccc2occ(CCN3CC=C(c4c[nH]c5ccccc45)CC3)c2c1 +NCCNc1ccc([N+](=O)[O-])c2[nH]c3ccccc3c(=O)c12 +COCC(C)n1c(-c2cn3c(C)nnc3c(NC(C)C)n2)nc2cnc(N3CCOCC3C)cc21 +O=S(=O)(c1ccccc1)n1ccc2c(N3CCN(CCCNc4c5c(nc6ccccc46)CCCC5)CC3)cccc21 +CCN(CC)CCOc1ccc(Nc2cc(N(C)C(=O)Nc3c(Cl)cccc3C(F)(F)F)ncn2)cc1 +N#CCCn1c(C(=O)N2CCC(C(N)=O)(N3CCCCC3)CC2)cc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +COc1cc(F)ccc1-c1ccnc2[nH]c(C3CNCCO3)cc12 +COc1cc(-c2cn(C3CCc4ccccc4N(CC(F)(F)F)C3=O)nn2)ccc1-c1ccncc1 +COc1cccc2[nH]c3c(N4CCC(C)CC4)ncnc3c12 +O=c1cc(-c2cccc(C=Cc3ccc4ccccc4n3)c2)oc2ccc(-c3nn[nH]n3)cc12 +COC(CC(CCN(C)Cc1ccc(-c2ccc(F)c(C)c2)cc1)C(=O)NO)c1ccc(F)cc1 +CN(c1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1)C1CCCCC1 +C#Cc1ccc2nc(-c3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)cn2c1 +Fc1ccc(-c2nn(CCCc3ccccc3)c3c2CNCC3)cc1 +COc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 +O=C(NCc1ccc(OC(F)(F)F)cc1)C1c2ccccc2C(=O)N1CCN1CCOCC1 +COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc5c(cn4)OCCO5)C(OC)C3)c2c1 +OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccc(F)c1 +Nc1nccc2c1CCC(C(=O)NC(Cc1ccccc1)c1nc(-c3ccc4c(N)n[nH]c4c3)c(Cl)[nH]1)C2 +COc1ccc(COc2nc(N3CCC4(CC4)C3)ncc2C(=O)NCc2ccc(F)cc2)cc1Cl +O=C(Nc1ccc(C(=O)N2CCN(c3ccc(Cl)cn3)CC2)cc1)N1Cc2ccccc2C1 +CCOC(CC(=O)O)c1ccc(OCc2cccc(OCOC)c2)cc1 +Nc1nc(N)c2cc(S(=O)(=O)c3ccc4ccccc4c3)ccc2n1 +Cc1nc(N)nc(-c2cc(CN3CCN(S(C)(=O)=O)CC3)cnc2Nc2cn[nH]c2)n1 +COc1cccc(C#CCOC(=O)c2c(O)nc3cc(Cl)ccc3c2O)c1 +CCCN(CCC1CCC(NC(=O)C=Cc2cccc(Cl)c2)CC1)C1CCc2nc(N)sc2C1 +CCCS(=O)(=O)Nc1cccc(Nc2ncnc3cc(OC)c(OC)cc23)c1 +C=CS(=O)(=O)N(C)C1CCN2CCc3ccccc3C2C1 +COc1ccc(CN2CCOC(COc3ccccc3)C2)cc1Cl +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccccc3)sc12 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(C)c4cc(Cl)ccn4)ncc23)ccn1 +CN1CCC(N(C)C(=O)c2cccc(Nc3nc4nc5c(cnn35)CCCCC(=O)Nc3cccc(c3)N4)c2)C1 +COc1ccc(CN2CCc3nc(N4CCCCC4)sc3C2)cc1 +Cc1ccc(-c2c(CN)c(CC(C)(C)C)nc(CC(C)C)c2C(=O)O)cc1 \ No newline at end of file diff --git a/Experiments/BACE/running utils/vocab.csv b/Experiments/BACE/running utils/vocab.csv new file mode 100644 index 0000000000000000000000000000000000000000..a8d112ae53e12daec50e4a32374afc22776e5794 --- /dev/null +++ b/Experiments/BACE/running utils/vocab.csv @@ -0,0 +1,2787 @@ +,Functional grp name,SMARTS,Smiles +0,Acid halides,"[F,Cl,Br][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +1,Acid azides,"[CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C=O +2,Sulphonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[Cl,Br]",*S(C)(=O)=O +3,Sulphonyl azides,"[Sv6X4](=[OX1])(=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",*S(=O)=O +4,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +5,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O +6,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1 +7,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O +8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1 +9,Thioesters,[CX3](=[SX1])[SX2],SC=S +10,Haloalkanes,"[CX4][Cl,Br,I]",*C +11,Dialkylsulfates/ sulfonates,"[$([#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6]),$([#6][Sv6X4](=[OX1])(=[OX1])[OX2][#6])]",* +12,N-Trihalomethyl imides,"[CX3](=[OX1])[NX3]([CX4]([Cl,Br,I])([Cl,Br,I])[Cl,Br,I])[CX3](=[OX1])",*C(*)(*)N(C=O)C=O +13,Quinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]",* +14,Hydroquinones and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1][cR1][cR1]([OX2][#1,CX4])[cR1][cR1]1",*Oc1ccc(O*)cc1 +15,Catechols and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1]([OX2][#1,CX4])[cR1][cR1][cR1][cR1]1",*Oc1ccccc1O* +16,"α, β-Unsaturated aldehydes, amides, esters and ketones","[$([CX3]([#6,$([NX3]([CX3]=[OX1])([#6])[#6]),$([OX2]([CX3]=[OX1])[#6]);!$([OH][CX3]=[OX1]);!$([O-][CX3]=[OX1])])(=[OX1])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX3H1](=[OX1])[CX3]([#6,#1])=[CX3])]",* +17,"Precursors of α, β-unsaturated aldehydes, amides, esters and ketones (1)","[$([CX4]([OX2])([OX2])([#6,#7,#8])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX4H1]([OX2])([OX2])[CX3]([#6,#1])=[CX3])]",* +18,"1,3-Diketones","[CX4,a!r0][CX3](=[OX1])[CH2][CX3](=[OX1])[CX4,a!r0]",*C(=O)[CH2]C(*)=O +19,Aldehydes,"[CX3]([H])(=[OX1])[#1,CX4,a!r0]",*C([H])=O +20,Ketones,"[CX4,a!r0][CX3](=[OX1])[CX4,a!r0]",*C(*)=O +21,Formaldehyde donors,"[$([NX3][CH2][NX3]),$([NX3][CH2][OX2]),$([CX4]([F,Cl,Br,I])([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])[CH2][OH1])]",* +22,Precursors of aldehydes and ketones,"[CX4]([OX2])([OX2])([CX4,a!r0])[CX4,a!r0]",*C(*)(O)O +23,Enol precursor of aldehydes and ketones,"[CX3]=[CX3]([#6,#1])[OX2]",*C(=C)O +24,Aromatic primary and secondary amines,"[a!r0][$([NX3H2]),$([NX3H1][CX4,a!r0])]",** +25,N-Haloimides,"[CX3](=[OX1])[NX3]([Cl,Br])[CX3](=[OX1])",*N(C=O)C=O +26,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl +27,Disullides,"[CX4,a!r0][SX2][SX2][CX4,a!r0]",*SS* +28,Phenyl carbonates,"c1ccccc1[OX2][CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)Oc1ccccc1 +29,Epoxides,[CX4]1[CX4][OX2]1,C1CO1 +30,1.2-Dicarbonyls,"[CX4,a!r0][CX3](=[OX1])[CX3](=[OX1])[#1,CX4,a!r0]",*C(=O)C(*)=O +31,Thiazolones,"[$([SX2]1[CX3]([CX4,a!r0])=[CX3]([CX4,a!r0])[CX3](=[OX1])[NX3]1([CX4,a!r0])),$([sX2]1[cX3]([CX4,a!r0])[cX3]([CX4,a!r0])[cX3](=[OX1])[nX3]1([CX4,a!r0]))]",* +32,"1, 2-Diamines","[CX4,a!r0][NX3H1][CX4][CX4][NX3H1][CX4,a!r0]",*[NH]CC[NH]* +33,Quaternary ammonium cation,"[NX4+]([CX4,a!r0])([CX4,a!r0])([CX4,a!r0])[CX4,a!r0]",*[N+](*)(*)* +34,Activated N-heterocycle halides,"[$(n1c([F,Cl])ncnc1),$(n1c([F,Cl])ccnc1),$(n1c([F,Cl])nccc1)]",* +35,Aromatic sulphuric acids and salts,"[a!r0][Sv4X3](=[OX1])[$([OH]),$([O-])]",*S(*)=O +36,Iso(thio)cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +37,Acid imides,"[NX3]1([#1,#6])[CX3](=[OX1])[CX3]([!R])=[CX3]([!R])[CX3]1(=[OX1])",*C1=C(*)C(=O)N(*)C1=O +38,Activated N-heterocycles,"[$(n1c([F,Cl,$([CX2]#[NX1])])nccc1),$(n1cnccc1([F,Cl,$([CX2]#[NX1])])),$(n1cncnc1([F,Cl,$([CX2]#[NX1])]))]",* +39,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +40,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC +41,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1 +42,Aldehydes and precursors,"[$([#1,#6;!$(C=C);!$(C#C)][CX3]([H])(=[OX1])),$([CX4;H1]([OX2])[OX2])]",* +43,"α, β-Unsaturated carbonyls","[CX3]=[CX3][CX3](=[OX1])[$([OX2]([CX3]=[OX1])[!#1]),$([#1][CX3]=[OX1]),$([NX3H2]([CX3]=[OX1])),$([NX3]([CX3]=[OX1])),$([CX4][CX3]=[OX1])]",*C(=O)C=C +44,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +45,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH] +46,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1 +47,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1 +48,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1 +49,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH] +50,Thiols,[#16X2H1],[SH] +51,Disulfides,*[#16X2][#16X2]*,*SS* +52,Diaryl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[a!r0],*C(=O)OOC(*)=O +53,Arylacyl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[A],*C(=O)OOC(*)=O +54,Haloamides,"[#6][CX3](=[OX1])[NX3]([F,Cl,Br,I])[#6]",*N(C)C(C)=O +55,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH] +56,"1,2-Dihydroxy aromatic compounds",[OH1]aa[OH1],[OH]*:*[OH] +57,"1,4-Dihydroxy aromatic compounds",[OH1]aaaa[OH1],[OH]*:*:*:*[OH] +58,2 or 4-Hydroxysubstituted alkylphenyl ether,"[$(c1c([OX2][CX4])c([OH1])ccc1),$(c1c([OX2][CX4])ccc([OH1])c1)]",* +59,Aromatic amines,"[a!r0][$([NX3H2]),$([NX3H1][#6])]",** +60,Aromatic amines precursors,"[$([a!r0][NH1][CX3](=[OX1])),$(c1c([NX2]=[NX2][a!r0])ccc([$([NX3]([CX4])([CX4])),$([NX3H1][CX4]),$([NH2]),$([OH1])])c1)]",* +61,Alkyl or aryl sylfonyl halides,"[CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +62,Sulfonamides,"c1c([Sv6X4](=[OX1])(=[OX1])[NX3H1][$([#1]),$([CX4]),$([a!r0])])ccc([NX3H2])c1",*[NH]S(=O)(=O)c1ccc([NH2])cc1 +63,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S +64,Hydrazines,"[#6&!$([CX3]=[OX1,SX1,NX2])][NX3H1][NX3H2,$([NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])])]",*[NH]C +65,Aromatic nitro (general),"[a!r0][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",** +66,Aromatic amine (general),[a!r0][NX3H2],*[NH2] +67,Three-membered heterocycles (general),"[NX3H1,SX2,OX2]1[CX4][CX4]1",*1CC1 +68,Nitroso (general),[NX2]=[OX1],N=O +69,Unsubstituted heteroatom-bonded heteroatom (general),"[$([NX3H2]-[#7]),$([NX3H2]-[#8]),$([OX2H1]-[#7]),$([OX2H1]-[#8])]",* +70,Azo-type (general),[NX2]=[NX2],N=N +71,Aliphatic halide (general),"[CX4][Cl,Br,I]",*C +72,Polycyclic aromatic system (general),"[$([aR3]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))])]",* +73,Aromatic nitroso (specific),[a!r0][NX2]=[OX1],*N=O +74,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O +75,Nitrosamine (specific),"[OX1]=[NX2][NX3]([#6,#1])[#6,#1]",*N(*)N=O +76,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1 +77,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1 +78,Azide (specific),"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +79,Diazo (specific),"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +80,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N +81,Aromatic hydroxylamine (specific),[a!r0][NX3H1][OH1],*[NH][OH] +82,Aliphatic halide (specific),"[Cl,Br,I][$([CX4]);!$([CX3](=[OX1,SX1,NX2]));!$([CH2][CH2][SX2,NX3])]",** +83,Carboxylic acid halide (specific),"[Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +84,Nitrogen and sulphur mustard (specific),"[Cl,Br,I][CH2][CH2][SX2,NX3]",*[CH2][CH2]* +85,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1 +86,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1 +87,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O +88,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O +89,Aliphatic N-nitro (additional),"[NX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1][O-]))]",*N +90,Diazonium (additional),"[$([a!r0][NX2+]#[NX1]),$([a!r0][NX2]#[NX1])]",* +91,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +92,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH] +93,1-Aryl-2-monoalkyl hydrazine (additional),[a!r0][NX3H1]-[NX3H1][CX4],*[NH][NH]C +94,Aromatic methylamine (additional),[a!r0][NX3;H1][CH3],*N[CH3] +95,Aromatic hydroxylamine ester (additional),[a!r0][NH][OX2][CX3](=[OX1]),*[NH]OC=O +96,Polycyclic planar system (additional),[*R1]1[*R2]2=[*R1][*R1]=[*R1][*R1]=[*R2]2[*R1][*R2]3=[*R1][*R1]=[*R1][*R1]=[*R2]13,*1*2=**=**=*2**2=**=**=*12 +97,Acyl halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +98,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +99,Monohaloalkene,"[CX3]([CX4,#1])([F,Cl,Br,I])=[CX3]([CX4,#1])[!F!Cl!Br!I]",*C(*)=C(*)* +100,S or N mustard,"[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +101,Propiolactones or propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +102,Epoxides and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +103,Aliphatic halogens,"[CX4;!H0][Br,Cl,I]",*C +104,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O +105,Simple aldehyde,"[CX3]([H])(=[OX1])[#1,#6&!$([CX3]=[CX3])]",*C([H])=O +106,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN +107,Aliphatic azo and azoxy,"[$([C,#1][NX2]=[NX2][C,#1]),$([CX3]=[NX2+]=N),$([CX3]=[NX2+]=[NX1-]),$([CX3-][NX2+]#[NX1]),$([CX3][NX2]#[NX1]),$(C[NX2]=N(=O)[*]),$(C[NX2]=[N+]([O-])[*])]",* +108,Isocyanate and isothiocyanate groups,"[NX2]=[CX2]=[OX1,Sv2X1]",*=C=N +109,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +110,Thiocarbonyl,"[$([NX3][CX3](=[Sv2X1])[NX3]),$([CX3;!$(C[OH]);!$(C[SH]);!$(C[O-]);!$(C[S-]);!$(CO[#6])](=[Sv2X1])[NX3])]",* +111,Heterocyclic polycyclic aromatic hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +112,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O +113,Azide and triazene groups,"[$([NX2!R]=[NX2!R][NX3!R]),$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",* +114,Aliphatic N-nitro group,"[NX3]([#1,C])([#1,C])[$([NX3+](=[OX1])[O-]),$([NX3](=O)=O)]",*N(*)* +115,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC +116,Aromatic nitroso group,[a!r0][NX2]=[OX1],*N=O +117,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +118,Coumarins and furocoumarins,"[$(c1cccc2c1oc(=O)cc2),$(C1=CC(=O)OC2=CC=CC=C12),$(C1=CC(=O)Oc2ccccc12)]",* +119,Halogenated benzene,"c1ccccc1[$([Br,Cl,F,I]);!$([Br,Cl,F,I]aa[Br,Cl,F,I]);!$([Br,Cl,F,I]aaa[Br,Cl,F,I]);!$([Br,Cl,F,I]aa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aaa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aa([OH])a([OH])aa[OH])]",*c1ccccc1 +120,Halogenated PAH,"[Br,Cl,F,I][$([cR1]1[cR1][cR1][cR1][cR1][cR1]1-[cR1]2[cR1][cR1][cR1][cR1][cR1]2),$([cR1]1[cR1][cR1][cR1][cR2]2[cR2]1[cR1][cR1][cR1][cR1]2)]",** +121,Halogenated dibenzodioxins,"[OR1]1[CR2]2=[CR1][CR1]=[CR1][CR1]=[CR2]2[OR1][CR2]3=[CR1][CR1]([F,Cl,Br,I])=[CR1][CR1]=[CR2]13",*C1=CC=C2OC3=CC=CC=C3OC2=C1 +122,Primary and secondary aromatic amines,"[$([a!r0][NX3;H2]),$([a!r0][NX3;H1][CH3]),$([a!r0][NX3;H1][CH2][CH3])]",* +123,Tertiary aromatic amines,"a[NX3]([$([CH3]),$([CH2][CH3])])[$([CH3]),$([CH2][CH3])]",*N(*)* +124,Secondary aromatic acetamides and formamides,"[$([a!r0][NX3;H1][CX3;H1](=[OX1])),$([a!r0][NX3;H1][CX3](=[OX1])[CH3])]",* +125,Nitroarenes,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=O)(=O))]",** +126,Nitrosoarenes,[a!r0][NX2]=[OX1],*N=O +127,Arylhydroxylamines,"[a!r0][NX3;H1][OX2][#1,#6]",*NO* +128,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O +129,N-Nitroso-N-alkylamides,"[CX4,a!r0][CX3](=[OX1])[NX3]([CX4])[NX2]=[OX1]",*C(=O)N(C)N=O +130,N-Nitroso-N-alkylureas,"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[NX3H1][CX4,a!r0]",*[NH]C(=O)N(C)N=O +131,N-Nitroso-N-alkylcarbamates (aka urethanes),"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)N(C)N=O +132,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O +133,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O +134,Benzylic halides,"[a!r0][CH2][Cl,Br,I]",*[CH2]* +135,Oxiranes and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +136,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +137,Alkyl esters of sulfonic and sulphuric acids,"[$([CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,a!r0][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])])]",* +138,Alkyl esters of phosphonic and phosphoric acids,"[$([CX4,a!r0][Pv5X4](=[OX1])([OX2][$([CH3]),$([CH2][CH3])])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,#1][OX2][Pv5X4](=[OX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])])]",* +139,Mixed alkyl esters of thiophosphoric acid,"[CX4][OX2][Pv5X4](=[SX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])]",*OP(=S)(O*)OC +140,Haloethylamines,"[NX3]([#1,#6])([#1,#6])[CH2][CH2][Cl,Br,I,F]",*[CH2][CH2]N(*)* +141,Haloalkylethers,"[$([#6][OX2][CH2][CH2][Cl,Br,I]),$([#6][OX2][CH2][Cl,Br,I])]",* +142,α-Halocarbonyl or a-halohydroxy,"[$([CX3](=[OX1])[CH2][Cl,Br,I]),$([CX4!H0]([OH1])[CH2][Cl,Br,I])]",* +143,Haloamines,"[#6][NX3]([#6])[Cl,Br,I,F]",*N(C)C +144,Allylic halides and alkoxides,"[CX3]=[CX3][CH2][$([Cl,Br,I]),$([OX2])]",*[CH2]C=C +145,Halogenated methanes,"[CX4]([H,F,Cl,Br,I])([H,F,Cl,Br,I])([H,F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)* +146,Vinyl halides,"[CX3]=[CX3H1][Cl,Br,I]",*[CH]=C +147,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O +148,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S +149,Alkyl esters of phosphonic or sulphonic acids,"[$([CX4,a][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]),$([CX4,a][Pv5X4](=[OX1])([OX2][#1,CX4])[OX2][CX4])]",* +150,Aromatic nitro groups,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=[OX1])=[OX1]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +151,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +152,Aromatic mono- and dialkylamino groups,"[a!r0][$([NX3H1][CH3]),$([NX3H1][CH2][CH3]),$([NX3]([CH3])[CH3]),$([NX3]([CH3])[CH2][CH3]),$([NX3]([CH2][CH3])[CH2][CH3]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +153,Alkyl hydrazines,"[NX3]([CX4])([#1,CX4])[NX3]([#1,CX4])[#1,CX4]",*N(*)N(*)C +154,Alkyl aldehydes,"[$([CX3]([H])(=[OX1])[#1,CX4])&!$([CX3]([H])(=[OX1])[CX3]=[CX3])]",* +155,Monohaloalkenes,"[CX3]([CX4,#1])(Cl)=[CX3]([!F!Cl!Br!I])[CX4,#1]",*C(*)=C(*)Cl +156,"β-Haloethyl N, S - mustards","[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +157,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl +158,Propiolactones and propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +159,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1 +160,Aromatic and aliphatic substituted primary alkyl halides,"[F,Cl,Br,I][CH2][CX4,a]",*[CH2]* +161,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O +162,Aliphatic and aromatic epoxides,"[$([CX4]1[OX2][CX4]1),$([#6]1=[#6][#8]1)]",* +163,Activated halo- or nitropyridines,"[$(c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])cc1),$(c1([F,Cl,Br,I,$(N(=O)=O)])ncccc1([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)]))]",* +164,2-Halo- or 2-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncccn1",*c1ncccn1 +165,4-Halo- or 4-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncncc1",*c1ccncn1 +166,Activated 2-halo- or 2-nitropyrazines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])nc1",*c1cnc(*)cn1 +167,Halo- or nitro s-triazines,"c1nc([F,Cl,Br,I,$(N(=O)=O)])ncn1",*c1ncncn1 +168,Formaldehyde and thioformaldehyde,"[CH2]=[OX1,SX1]",*=C +169,Aliphatic aldehydes and thioaldehydes,"[CX4][CX3H1]=[OX1,SX1]",*=[CH]C +170,Aromatic aldehydes,[a][CX3H1]=[OX1],*[CH]=O +171,"α, β-Unsaturated carbonyl and thiocarbonyl compounds","C(C)(C)=CC=[OX1,SX1]",*=CC=C(C)C +172,"α, β-Unsaturated ketones and thioketones","[C;!r5]([C;!r5])=[C;!r5][C;!r5](C)=[OX1,SX1;!r5]",*=C(C)C=CC +173,α-Diketones and α-dithiones,"[#6]C(=[OX1,SX1])C(=[OX1,SX1])[#6]",*=C(C)C(=*)C +174,β-Diketones and β-dithiones,"[#6]C(=[OX1,SX1])[CX4]C(=[OX1,SX1])[#6]",*=C(C)CC(=*)C +175,"C-Nitroso compounds, iso(thio)cyanates, (thio)cyanate esters","[#6][$([NX2]=O),$(N=C=O),$(OC#N),$(SC#N),$(N=C=S)]",*C +176,Primary alkyl amines,[CH2][NH2],[CH2][NH2] +177,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3] +178,"α, β-Unsaturated alkoxy","[$(CC(C)=[CH][CH2][OH]),$(CC=C(C)[CH2][OH])]",* +179,Three-membered heterocycles derivatives,"[CH,CH2,CH3;!$([CH2]CC=[O,S])]([F,Cl,Br,I,$(OS(=O)(=O)[#6,#1]),$(OS(=O)(=O)O[#6,#1])])[#6]1[O,N,SX2][#6]1",**C1*C1 +180,Lactones and their thio analogues,"C1C(=[O,S])[O,S][CH2,CH]1",*=C1**C1 +181,Esters of aromatic and unsaturated alcohols and their thio analogues,"[$(C=C),$(C#C),a][CH2,CH][O,S][$([CH]=O),$([CH]=S),$(C(C)=O),$(C(C)=S)]",**** +182,Aryloxy (arylthio) containing unsaturated compounds,"[$(C=C),$(C#C),a][CH2,CH][O,S][a]",**** +183,Aliphatic N-(thio)nitroso compounds,"[CH2,CH3][NX3][NX2]=[O,S]",*NN=* +184,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1 +185,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +186,Activated alkene (Michael acceptor) (1),"[CH2,CH]=[CH][$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*[CH]=* +187,Activated alkene (Michael acceptor) (2),"[CH2]=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C +188,Activated alkene (Michael acceptor),"aC=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C* +189,Activated alkine,"C#C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C#C +190,Activated conjugated dienes,"[CH2,CH]=[CH]C=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C[CH]=* +191,Alkenes containing a gem-dihalo-substituted terminal double bond,"C=C([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)=C +192,Ortho-disubstituted benzenes,"c1c([O,NH2,NH])c([O,NH2,NH])ccc1",*c1ccccc1* +193,Para-disubstituted benzenes,"c1c(=[O,NH2,NH])ccc(=[O,NH2,NH])c1",*=c1ccc(=*)cc1 +194,Haloanhydrides,"[F,Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +195,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1 +196,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21 +197,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +198,Phosphorus halogen derivatives (1),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#6])[#6]",*P(C)(C)=O +199,Phosphorus halogen derivatives (2),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#6]",*P(C)(O)=O +200,Phosphorus halogen derivatives (3),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#8]",*P(O)(O)=O +201,Phosphorus halogen derivatives (4),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#7])[#6]",*P(C)(N)=O +202,Phosphorus halogen derivatives (5),"[Pv5X4]([F,Cl,Br,I])([#6])([#6])=[SX1]",*P(C)(C)=S +203,Phosphorus halogen derivatives (6),"[Pv5X4]([#8])([#6])([F,Cl,Br,I])(=[SX1])",*P(C)(O)=S +204,Phosphorus halogen derivatives (7),"[Pv5X4](=[SX1])([F,Cl,Br,I])([#16])[#6]",*P(C)(S)=S +205,Phosphorus V derivatives,[Pv5X4]([!#1])([!#1])([!#1])=[NX2],*P(*)(*)=N +206,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC +207,Thiocyanates,[SX2][CX2]#[NX1],N#CS +208,Sulfonylhalides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +209,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O +210,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +211,Alkylsulfates,"[#6,#1][OX2,OH1][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]",**S(=O)(=O)OC +212,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O +213,All types of 3-valent phosphorus and similar (2),"[Pv3X3]([#8])([#8])[F,Cl,Br,I]",*P(O)O +214,All types of 3-valent phosphorus and similar (3),"[Pv3X3]([#8])([#6])[F,Cl,Br,I]",*P(C)O +215,All types of 3-valent phosphorus and similar (4),"[Pv3X3]([#6])([#6])[F,Cl,Br,I]",*P(C)C +216,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C +217,All types of 3-valent phosphorus and similar (6),"[Pv3X3]([#8])([#7])[F,Cl,Br,I]",*P(N)O +218,All types of 3-valent phosphorus and similar (7),"[Pv3X3]([#7])([#7])[F,Cl,Br,I]",*P(N)N +219,All types of 3-valent phosphorus and similar (8),"[#16][Pv3X3]([#6])[F,Cl,Br,I]",*P(C)S +220,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N +221,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C +222,Hydroxamic acid haloanhydrides,"[CX3]([#6])([F,Cl,Br])=[NX2][#8]",*C(C)=NO +223,Halothioanhydrides,"[#6][CX3](=[SX1])[F,Cl,Br,I]",*C(C)=S +224,Halocarbonates,"[#8][CX3](=[OX1])[F,Cl,Br,I]",*C(O)=O +225,Halocarbamates,"[#7][CX3](=[OX1])[F,Cl,Br,I]",*C(N)=O +226,Isocyanides,"[#6][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +227,Azides,"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +228,Thione esters,"[#6,#1][CX3](=[SX1])[OX2][#6]",*C(=S)OC +229,Acylsulfides,"[#6,#1][CX3](=[OX1])[SX2][#6]",*C(=O)SC +230,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S +231,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S +232,Peroxides,[OX2][OX2],OO +233,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS +234,Nitroso,[#6][NX2]=[OX1],CN=O +235,Nitrates,"[#6][OX2][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*OC +236,N-Nitro,"[#7][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*N +237,N-Nitroso,[#7][NX2]=[OX1],NN=O +238,Azo,[#6][NX2]=[NX2][#6],CN=NC +239,Azoxy,"[#6][$([NX2]=[NX3+]([O-])[#6]),$([NX2]=[NX3](=[OX1])[#6])]",*C +240,Nitroso dimers,"[$([#6][NX3+]([OX1-])=[NX3+]([OX1-])[#6]),$([#6][NX3](=[OX1])=[NX3](=[OX1])[#6])]",* +241,Sulfenyl halides,"[#6][Sv2X2][F,Cl,Br,I]",*SC +242,Sulfinyl halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +243,Diazonium salts,"[$([NX2+]#[NX1]),$([NX2]#N)]",* +244,Cyclic and linear haloamidines,"[CX3](=[#7])([#7])[Cl,Br,I]",*C(N)=N +245,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC +246,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C +247,Hydroxylamines,[OH1][NX3][#6],CN[OH] +248,N-Oxides,"[$([OX1-,OH1][#7X4+]([*])([*])([*])),$([OX1]=[#7X4v5]([*])([*])([*])),$([OX1]=[Nv5X3&!$([Nv5X3](=[OX1])=[OX1])](=[*])([*])),$([OX1-,OH1][#7X3+R](~[R])(~[R])),$([OX1]=[#7v5X3R](~[R])(~[R]))]",* +249,Aminals,N[CX4]N,NCN +250,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C +251,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C +252,α-Haloketones and similar,"[#6][CX3](=[OX1])[CX4][Cl,Br,I]",*CC(C)=O +253,β-Haloamines,"[NX3][CX4][CX4][Cl,Br,I]",*CCN +254,β-Halosulfides,"[Sv2X2][CX4][CX4][Cl,Br,I]",*CCS +255,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O +256,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O +257,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C +258,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O +259,Nitrovinyl,"[CX3]=[CX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +260,Acrylonitriles,[NX1]#CC=C,C=CC#N +261,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O +262,Vinylpyridines and similar,"[$(n1c([CX3]=[CX3])cccc1),$(n1cc([CX3]=[CX3])ccc1),$(n1ccc([CX3]=[CX3])cc1)]",* +263,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1 +264,Ketenes,[CX3]=[CX2]=[OX1],C=C=O +265,Allenes,C=C=C,C=C=C +266,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1 +267,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1 +268,Aziridines,[CX4]1[NX3][CX4]1,C1CN1 +269,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1 +270,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1 +271,Selen in chain,[Sev2X2],[SeH2] +272,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O +273,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N +274,Benzylhalogenides and similar,"c1ccccc1([CX4][Cl,Br,I])",*Cc1ccccc1 +275,Halomethyl ethers,"[F,Cl,Br,I][CX4][#8]",*CO +276,Halomethyl thioethers,"[F,Cl,Br,I][CX4][#16]",*CS +277,Halomethyl amines,"[F,Cl,Br,I][CX4][#7]",*CN +278,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O +279,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S +280,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S +281,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S +282,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S +283,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O +284,Positively charged N-heterocycles,[#7v4X3R],N +285,Organometallic compounds,"[$([Te]~[#6]),$([As]~[#6]),$([Ge]~[#6]),$([Hg]~[#6]),$([Co]~[#6]),$([Fe]~[#6]),$([Mn]~[#6]),$([Cr]~[#6]),$([Ti]~[#6]),$([Sn]~[#6])]",* +286,"Isothiazolinone, isothiazolinthione and their derivatives","[#6]1=,:[#6]C(=[OX1,SX1])N[SX2]1",*=C1C=CSN1 +287,Acyl and thioacyl halides,"[!$(C=C);!$(C#C)]C(=[O,SX1])[F,Cl,Br,I]",*C(*)=* +288,Imidoyl halides,"[!$(C=C);!$(C#C)]C(=N)[F,Cl,Br,I]",*C(*)=N +289,Esters of aromatic alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][a]",**C(*)=* +290,Acid anhydrides and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N]C(=[O,SX1,N])",*C(=*)*C=* +291,Esters of unsaturated alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,S,N])[O,S][$(C=C),$(C=N),$(C#C),$(C#N)]",**C(*)=* +292,"β-Lactones, β-lactams and their thio analogues","[#6]1C(=[O,S])[O,N,S][#6]1",*=C1*CC1 +293,Benzo-fused five-membered heterocycles,"[C,N,O,S,a]c1[n,o,s]c2ccccc2[n,o,s]1",*c1*c2ccccc2*1 +294,(Thio)carbonyl and imine derivatives of five-membered heterocycles,"[#6]1[#6](=[N,O,S])[#7,#8,#16][#6][#7,#8,#16]1",*=C1*C*C1 +295,Phthalic anhydrides and their thio and aza analogues,"[C,O]=[#6]1[#7,#8,#16][#6](=[O,N,SX1])c2ccccc12",*=C1*C(=*)c2ccccc21 +296,Acylating agents,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][CX4,O,S][$(C=O),a,$(C=C),$(C#C),$(C=N),$(C#N)]",***C(*)=* +297,Heteryl-substituted benzenes,"C1=[C,N][$(S(=O)(=O)),$(C=[N,O]),$(S=O)][C,N]=C1c2ccccc2",*1*=CC(c2ccccc2)=*1 +298,Cyclopentanone and cyclopentathione derivatives,"[CH2,CH]=C1C(=[OX1,SX1])**C1",*=C1**CC1=* +299,"Ortho-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])c([OH,NH2,NH,$(N=N),$(N(C)C)])ccc1",*c1ccccc1* +300,"Para-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])ccc([OH,NH2,NH,$(N=N),$(N(C)C)])c1",*c1ccc(*)cc1 +301,"Meta-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])cc([OH,NH2,NH,$(N(C)C)])cc1",*c1cccc(*)c1 +302,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH] +303,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1 +304,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1 +305,Haloethyl-substituted aromatic compounds,"C([F,Cl,Br,I])[CH2,CH][a]",**C* +306,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1 +307,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1 +308,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12 +309,vic-Difluoroalkyl group,"F[CH2,CH]C(F)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(F)*F +310,vic-Dichloroalkyl group,"Cl[CH2,CH]C(Cl)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Cl)*Cl +311,vic-Dibromoalkyl group,"Br[CH2,CH]C(Br)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Br)*Br +312,vic-Diiodoalkyl group,"I[CH2,CH]C(I)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(I)*I +313,Carboxylic acid anhydrides,"[$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6]1),$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6][#6]1)]",* +314,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl +315,Lactones,"[$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6]1),$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6][#6]1)]",* +316,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O +317,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC +318,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC +319,Cyclic sulfonic acid esters,"[$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +320,Cyclic sulfuric acid esters,"[$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +321,Halo acetates,"[F,Cl,Br,I][#6][CX3](=[OX1])[OX2H1]",*CC(=O)[OH] +322,Halo acetamides,"[F,Cl,Br,I][#6][CX3](=[OX1])[NX3]",*CC(N)=O +323,Halo ethers,"[$([F,Cl,Br,I]C[OX2]C),$([F,Cl,Br,I]CC[OX2]C)]",* +324,Haloethyl sulfides (S-mustard),"[F,Cl,Br,I][CX4][CX4][SX2]",*CCS +325,Haloethyl amines (N-mustard),"[F,Cl,Br,I][CH2][CH2][NX3]",*[CH2][CH2]N +326,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O +327,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N +328,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C +329,"α, β-Unsaturated nitro compounds","[#6]=[#6][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +330,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O +331,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C +332,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH] +333,"α, β-Unsaturated carbonyl compounds",[#6]=[#6][CX3](=[OX1])([!#1!$([OH1])]),*C(=O)C=C +334,Alkyl halide,"[*!$([a])&!$(C=C)&!$(C#C)][CX4][F,Cl,Br,I]",*C* +335,Aryl halide,"[a!r0][F,Cl,Br,I]",** +336,Halogenated allylic group,"[F,Cl,Br,I][CX4][CX3]=[CX3]",*CC=C +337,Halogenated benzylic group,"c[CX4][F,Cl,Br,I]",*Cc +338,Diazo compounds,"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +339,Organo metallic compounds,"[$([Cu][#6]),$([Ag][#6]),$([Au][#6]),$([Zn][#6]),$([Cd][#6]),$([Hg][#6]),$([Sn][#6]),$([Pb][#6]),$([As][#6]),$([Sb][#6])]",* +340,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C +341,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C +342,Iodine,II,II +343,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H] +344,Sulfoxides,[Sv4X3](=[OX1]),O=S +345,Sulfenyl iodides,[SX2][IX1],SI +346,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS +347,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S +348,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS +349,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH] +350,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1 +351,(Dithio) carbamates,"[OX2,SX2][CX3](=[OX1,SX1])[NX3]",*C(=*)N +352,Organotin compounds,[Sn][#6],C[Sn] +353,Pyrethroids,"[$(CC(=C[CH]1C([CH]1C(=O)OC1C(=C(C(=O)C1)CC=CC=C)C)(C)C)C),$(C(=C[CH]1C([CH]1C(=O)O[CH]1C(=C(C(=O)C1)CC=CC=C)C)(C)C)(C)C(=O)OC)]",* +354,Organophosphorothionate esters,"[Pv5X4](=[SX1])([OX2][#6])([OX2,SX2][#6])([OX2,SX2][#6])",C*P(=S)(*C)OC +355,Acetates,"[CH,$([C!R](=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R,NX3!R][$([a;r6]),$([a;r5]),$(C=C),$(C#C)]",***=* +356,Acyclic anhydrides,"[CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R][CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])]=[O,SX1]",*=***=* +357,Dialkyl carbamoylhalides,"[NH2!R,$([NH!R](C=O)[#6!R]),$(N(C=O)([#6!R])[#6!R])]C(=O)[F,Cl,Br,I]",*C(*)=O +358,Phosphonic acid halides,"[#6]O[P!R](=O)(O[#6])[F,Cl,Br,I,$(C#N)]",*P(=O)(OC)OC +359,Cyclopropenones,"[#6]1([#1,#6])=,:[#6]([#1,#6])-,:[#6]1=O",*C1=C(*)C1=O +360,β-Lactones,C1C(=O)OC1,O=C1CCO1 +361,Thio-lactones,C1C(=O)SC1,O=C1CCS1 +362,Azlactones,"C1=[O,SX2,NX2,CX3]CC(=[O,SX2])[O,SX2,NX3]1",*=C1*C=*C1 +363,Cyclic anhydrides,"[#6R,#8R,#16X2R][#6R](=[O,SX1])[#8R,#16X2R][#6R]([#6,#8R,#16X2])=[#8,#16X1]",*C(=*)*C(*)=* +364,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC +365,Polarised alkene-aldehydes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][CH]=O",*=*[CH]=O +366,Polarised alkene-ketones,"[$([$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[#6]);!$([#6X3]1=,:[#6X3H][CX3](=[OX1])[#6X3]=,:[#6X3][#6X3]1(=[OX1]));!$([CX3]1(=[OX1])[CX3](=[OX1])[#6X3]=,:[#6X3H][#6X3]=,:[#6X3]1)]",* +367,Polarised alkene-esters,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)O[#6]",*=*C(=O)OC +368,Polarised alkene-amides,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)*=* +369,Polarised alkene-nitros,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",**=* +370,Polarised alkene-cyanos,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C#N",*=*C#N +371,Polarised alkene-alkyl sulphonates,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)O[#6]",*=*S(=O)(=O)OC +372,Polarised alkene-alkyl sulfones,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)[#6]",*=*S(C)(=O)=O +373,Polarised alkene-alkyl sulfinyls,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][SX3](=O)[#6]",*=*S(C)=O +374,Polarised alkene-oximes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C=[NX2][OH]",*=*C=N[OH] +375,Polarised alkene-pyridines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncccc1),$(c1ccncc1)]",**=* +376,Polarised alkene-pyrazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]c1nccnc1",*=*c1cnccn1 +377,Polarised alkene-pyrimidines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncc1),$(c1ncccn1),$(c1cncnc1)]",**=* +378,Polarised akene-triazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1),$(c1nnncc1),$(c1cnnnc1)]",**=* +379,Azocarbonamides,"[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]C(=O)N=NC(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)N=NC(*)=O +380,Allyl alcohols,"[CH2,$([CH](=C)[#6])]=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",*=*[CH2][OH] +381,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH] +382,Polarised alkyne-aldehydes,"[CH,$(C(#C)[#6])]#C[CH]=O",*#C[CH]=O +383,Polarise alkyne-ketones,"[CH,$(C(#C)[#6])]#CC(=O)[#6]",*#CC(C)=O +384,Polarised alkyne-esters,"[CH,$(C(#C)[#6])]#CC(=O)O[#6]",*#CC(=O)OC +385,Polarised alkyne-amides,"[CH,$(C(#C)[#6])]#CC(=O)[$([NH2]),$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)C#* +386,Polarised alkyne-nitros,"[CH,$(C(#C)[#6])]#C[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C#* +387,Polarised alkyne-cyano,"[CH,$(C(#C)[#6])]#CC#N",*#CC#N +388,Polarised alkyne-alkyl sulphonates,"[CH,$(C(#C)[#6])]#CS(=O)(=O)O[#6]",*#CS(=O)(=O)OC +389,Polarised alkyne-alkyl sulfones,"[CH,$(C(#C)[#6])]#CS(=O)(=O)[#6]",*#CS(C)(=O)=O +390,Polarised alkyne-alkyl sulfinyls,"[CH,$(C(#C)[#6])]#C[SX3](=O)[#6]",*#CS(C)=O +391,Polarised alkyne-pyridines,"[CH,$(C(#C)[#6])]#C[$(c1ncccc1),$(c1ccncc1)]",*C#* +392,Polarised alkyne-pyrazines,"[CH,$(C(#C)[#6])]#Cc1nccnc1",*#Cc1cnccn1 +393,Polarised alkyne-pyrimidines,"[CH,$(C(#C)[#6])]#C[$(c1ncccn1),$(c1cncnc1),$(c1ncncc1)]",*C#* +394,Polarised alkyne-triazines,"[CH,$(C(#C)[#6])]#C[$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1)]",*C#* +395,Propargyl alcohols,"[CH,$(C(#C)[#6])]#C[CH2][OH]",*#C[CH2][OH] +396,Benzoquinones,"[$(C1(=O)[#6]=,:[#6]C(=O)[CH]=C1),$(C1(=O)C(=O)[#6]=,:[#6][CH]=C1)]",* +397,Quinone-imines,"[$(C1(=O)[#6]=,:[#6][$(C=[NH]),$(C=N[CX4])][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])]C=[CH][#6]=,:[#6]1)]",* +398,Quinone-diimines,"[$([CH]1=C[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][$(C=[NH]),$(C=N[CX4])]1),$([CH]1=C[$(C=[NH]),$(C=N[CX4])][$(C=[NH]),$(C=N[CX4])][#6]=,:[#6]1)]",* +399,Aminophenols,"[$(c1([OH])c[cH]c([NH2])cc1),$(c1([OH])c([NH2])cc[cH]c1)]",* +400,Benzenediamines,"[$(c1([NH2])c[cH]c([NH2])cc1),$(c1([NH2])c([NH2])cc[cH]c1)]",* +401,Quinone-methides,"[$(C1=CC(=O)[#6]=,:[#6]C1(=[CH][CX4])),$(C1(=[CH][CX4])C(=O)[#6]=,:[#6]C=C1)]",* +402,Pyranones,"[$([cH]1cc(=[O,NH])cc[o,n]1),$([cH]1cc(=[O,NH])[o,n]cc1),$(c1cc(=[O,NH])[o,n][cH]c1)]",* +403,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1 +404,Mono-aldehydes,"[CH2,$([CH](=O)[CX4]),$([CH](=O)c1a(*)caaa1),$([CH](=O)c1a(*)aaa1)]=O",*=O +405,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2] +406,"Di-substituted α,β-unsaturated alkenes (polarized by an aldehyde moiety)","[$(C(=C)([#6])[#6]);!$(C(=C)([#6])C=[CH2,CH])]=C[CH]=O",*=C[CH]=O +407,Di-substituted allyl alcohols,"C([#6])([#6])=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",CC(C)=*[CH2][OH] +408,"1,2-Dicarbonyls","[CH,$(C(=O)(C=O)[CX4]),$(C(=O)(C=O)c1a(*)aaaa1),$(C(=O)(C=O)c1a(*)aaa1)](=O)[CH,$(C(=O)(C=O)[#6]);!$(C(=O)(C=O)C=[CH2,CH]);!$(C(=O)(C=O)C#C)]=O",O=**=O +409,"1,3-Dicarbonyls","[CH,$(C(=O)([CX4]C=O)[CX4]),$(C(=O)([CX4]C=O)c1a(*)aaaa1),$(C(=O)([CX4]C=O)c1a(*)aaa1)](=O)[CX4][CH,$(C(=O)([CX4]C=O)[#6]);!$(C(=O)([CX4]C=O)C=[CH2,CH]);!$(C(=O)([CX4]C=O)C#C)]=O",O=*C*=O +410,Ethylenediamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][NH2]),$([NH]1[CH2][CH2][NH][CH2][CH2]1)]",* +411,Ethanolamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][OH]),$([NH]1[CH2][CH2]O[CH2][CH2]1)]",* +412,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1 +413,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1 +414,Alkyl halides,"[CH3,$([CH2]([F,Cl,Br,I])[#6]),$([CH]([F,Br,Cl,I])([#6])[#6]);!$([CH2,CH]C=O);!$([CH2,CH][CX4][NX3,SX2]);!$([CH2,CH][CX4][F,Cl,Br,I])][F,Cl,Br,I]",** +415,Alkyl diazos,"[CH3,$([CH2](N=N)[#6]),$([CH](N=N)([#6])[#6])][NX2]=[NH,$(N(=N)[#6])]",*N=* +416,Alkyl sulfates,"[#6]OS(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(=O)(=O)OC +417,Alkyl sulphonates,"[#6]S(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(C)(=O)=O +418,Alkyl (thio)phosphates,"[#6][O,SX2]P(=[O,SX1])([O,SX2][#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(*C)*C +419,Alkyl (thio)phosphonates,"[#6][O,SX2]P(=[O,SX1])([#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(C)*C +420,Allyl acetates,"[#6]C(=[O,SX1])[O,SX2][CH2,$([CH]([O,SX2])[#6])][c,CX3,CX2]",***C(=*)C +421,α-Halocarbonyls,"[$([CH]=[O,SX1]),$(C([#6])=[O,SX1])][CH2,$([CH](C=[O,SX1])[#6])][F,Cl,Br,I]",*** +422,α-Haloalkynes,"[CH,$(C(#C)[#6])]#C[$([CH2](C#C)[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH](C#C)([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*C#* +423,α-Halobenzyls,"[c][$([CH2]([c])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH]([a])([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*c +424,Sulfuranes,C1[SX2]C1,C1CS1 +425,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1 +426,Nitrosoureas,"[NX3]C(=O)[$([NH](C=O)[NX2]=O),$(N(C=O)([#6])[NX2]=O)]",*C(N)=O +427,Nitrosoguanidines,"[NX3]C(=[NH])[$([NH](C=[NH])[NX2]=O),$(N(C=[NH])([#6])[NX2]=O)]",*C(N)=N +428,N-Acytoxy-N-acetylphenyls,"[a][NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)* +429,N-Acytoxy-N-alkoxyamides,"[#6]O[NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)OC +430,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O +431,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O +432,Aromatic sulphonic acids,[a][SX4](=O)(=O)[OH],*S(=O)(=O)[OH] +433,Isothiazol-3-ones,"[cH,$(c(c)([sX2])[#6])]1[cH,$(c(c)(c=O)[#6])]c(=O)[nH,$(n(c=O)([sX2])[#6])][sX2]1",O=c1*:*s*1 +434,Isothiazolin-3-ones,"[CH2,$([CH](C)([SX2])[#6])]1[CH2,$([CH](C)(C=O)[#6])]C(=O)[NH,$(N(C=O)([SX2])[#6])][SX2]1",O=C1**S*1 +435,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl +436,Polarized alkenes with a halogen leaving group,"C=[CH][F,Cl,Br,I]",*[CH]=C +437,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C +438,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C +439,Polarized alkenes with an alkyl (thio)phosphonate leaving group,"C=[CH]OP(=[O,SX])(O[#6])[#6]",*=P(C)(OC)O[CH]=C +440,Polarized alkenes with an alkyl (thio)phosphate leaving group,"C=[CH]OP(=[O,SX])(O[#6])O[#6]",*=P(OC)(OC)O[CH]=C +441,Mustards,"[NX3,SX2][CH2,$([CH]([NX3,SX2])([CX4])[CX4])][CH2,$([CH]([CX4])([Cl,Br,I])[CX4])][Cl,Br,I]",**** +442,"1,2-Dihaloalkanes","[Cl,Br,I][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][Cl,Br,I]",**** +443,Activated pentafluorobenzenes,"c1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-]),$([CH]=O),$(C#N),$(C(=O)[CH3])])c(F)c(F)c(F)c(F)c1(F)",*c1c(F)c(F)c(F)c(F)c1F +444,Formaldehyde releasers (1),"[$(O1COCC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C1),$([OX2H1]CC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C[OX2H1])]",* +445,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH] +446,Formaldehyde releasers (3),"C1(=[OX1])[NX3H1]C(=[OX1])[NX3H1][CX4]1(C[OH1])[NX3H1][CX3](=[OX1])[NX3!H0][#1,#6]",*NC(=O)[NH]C1(C[OH])[NH]C(=O)[NH]C1=O +447,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH] +448,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1 +449,"Hydrazine, hydrazides","[#6,#1][NX3H1][NX3H1][#6,#1]",*[NH][NH]* +450,Nitrobenzenes,"a[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",** +451,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21 +452,Benzylamines,"[#1,CX4!R][NX3]([#1,CX4!R])[CH2]c1ccccc1",*N(*)[CH2]c1ccccc1 +453,Propargyl amines,"[#1,CX4,$(c1ccccc1)][CX2]#[CX2][NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*C#CN(*)* +454,Cyclopropyl amines,"[CX4]1[CX4][CX4]1[NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*N(*)C1CC1 +455,"N-Substituted-4-aryl-1,2,3,6-tetrahydropyridines","[NX3]1([CX4!R])[CX4][CX3]=[CX3](c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2=CCN(C)CC2)c(*)c1* +456,N-Substituted-4-arylpiperidin-4-ol,"[NX3]1([CX4!R])[CX4][CX4][CX4]([OH1])(c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2([OH])CCN(C)CC2)c(*)c1* +457,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O +458,Hydantoins (glycolylurea),"[NX3H1]1[CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NX3H1][CX3]1(=[OX1])",*C1(*)[NH]C(=O)[NH]C1=O +459,Thioureas,"[#1,#6][NX3]([#1,#6])[CX3](=[SX1])[#7]",*N(*)C(N)=S +460,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O +461,Ortho- or parahydroquinones,"[$(c1([OH1])c([OH1])cccc1),$(c1([OH1])ccc([OH1])cc1)]",* +462,Ortho- or paraquinones,"[$([#6]1(=[OX1])-,:[#6]=,:[#6]-,:[#6](=[OX1])-,:[#6]=,:[#6]1),$([#6]1(=[OX1])-,:[#6](=[OX1])-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)]",* +463,Ortho- or paraalkylphenols,"[$(c1([OH1])c([CX4]([#1,#6])[#1,#6])cccc1),$(c1([OH1])ccc([CX4]([#1,#6])[#1,#6])cc1)]",* +464,Quinone methide,"[$([OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]-,:[#6X3]1=[CX3]([#1,#6])[#1,#6]),$([OX1]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[CX3]([#1,#6])[#1,#6])-,:[#6]=,:[#6]1)]",* +465,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1 +466,3-Methylene indoles,"c1ccc([nX3]2([#1,#6]))c(c([CH2][#1,#6])c2)c1",*[CH2]c1cn(*)c2ccccc12 +467,Furans,c1ccc[oX2]1,c1ccoc1 +468,Thiophenes,c1ccc[sX2]1,c1ccsc1 +469,Thiazoles and 2-amino derivatives,"[$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([#1,CX4!R])[sX2]1),$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([NX3]([#1,CX4!R])[#1,CX4!R])[sX2]1)]",* +470,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O +471,2- or 4-Halopyridines,"[$(n1c([Cl,Br,I,F])cccc1),$(n1cccc([Cl,Br,I,F])cc1)]",* +472,Alkynes,"[#6][CX2]#[CX2][#1,#6]",*C#CC +473,Alkylhalides,"[$([CX4]([F,Cl,Br,I])([H,!F!Cl!Br!I])([H,!F!Cl!Br!I])[H,!F!Cl!Br!I]),$([CX4]([#6])([F,Cl,Br,I])([F,Cl,Br,I])[H,!F!Cl!Br!I])]",* +474,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH] +475,Fluoroethyl ethers and amines,"[$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][OX2][#1,#6]),$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][NX3][#6])]",* +476,Three-membered heterocycles,"[#6]1~[#6][#7,#8,#16]1",*1C~C1 +477,Thioles,[Sv2X2H1],[SH] +478,Chlor(brom)anhydrides,"[CX3](=[OX1])[Cl,Br]",*C=O +479,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O +480,Trihalogensubstituted ketones,"[CX3](=[OX1])[CX4]([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C=O +481,Monohalogen substituted ketones,"[CX3](=[OX1])C[Cl,Br,I]",*CC=O +482,Sulphonhalogenanhydrides,"S(=[OX1])(=[OX1])[F,Cl,Br,I]",*S(=O)=O +483,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH] +484,Phosphorus,P,P +485,Selen,[Se],[SeH2] +486,Bor,B,B +487,Silicium,[Si],[SiH4] +488,"Isocyanates, isothiocyanates","[NX2]=[CX2]=[OX1,SX1]",*=C=N +489,Thione,[CX3]=[SX1!R],C=S +490,β-halogen substituted carbonyls,"[CX3](=[OX1])CC[F,Cl,Br,I]",*CCC=O +491,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH] +492,gem-Dihalo propane and cyclopropane,"CC([Cl,Br,I])([Cl,Br,I])C",*C(*)(C)C +493,Activated halides (o-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cc[F,Cl,Br]",*cc* +494,Activated halides (p-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cccc[F,Cl,Br]",*cccc* +495,Activated halides (α-halogen substituted N-heterocycles),"nc[F,Cl,Br]",*cn +496,Activated halides (γ-halogen substituted N-heterocycles),"nccc[F,Cl,Br]",*cccn +497,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S +498,Barbiturates,"N1C(=[OX1,SX1])NC(=[OX1,SX1])C(=C)C1(=[OX1,SX1])",*=C1NC(=*)C(=C)C(=*)N1 +499,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2] +500,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O +501,Crown ethers,[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C,*C~C*C~C*C~C*C~C*C~C*C~C +502,Coumarins (1),"c1cccc2c1oc(=O)c([$(C=[OX1]),$(C=[SX1]),$(S=[OX1]),$(C#[NX1]),F,Cl,Br,I,$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]));!$([CX3](=[OX1])[OH1])])[c!H0]2",*c1cc2ccccc2oc1=O +503,Coumarins (2),"[cH1]1[cH1]c2c3[cH1][cH1]c(cc3oc(=O)c2[cH1]c1[OX2][$([CH2]),$([CH3])])[OX2][C!H0]",*Oc1[cH][cH]c2c([cH]1)c(=O)oc1cc(OC)[cH][cH]c12 +504,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1 +505,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1 +506,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1 +507,Coumarins (6),"c1([F,Cl,Br,I])cc([F,Cl,Br,I])cc2c1oc(=[NX2H1])c([CX3](=[OX1])[NH2])[c!H0]2",*c1cc(*)c2oc(=N)c(C([NH2])=O)cc2c1 +508,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1 +509,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1 +510,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O +511,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N +512,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O +513,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N +514,o-Quinones (3),"CC(=[OX1])C(=[OX1])[#6,#7]",*C(=O)C(C)=O +515,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S +516,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12 +517,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O +518,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH] +519,N-N Single bound not in a ring,[N!R][N!R],NN +520,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC +521,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O +522,Acyl and sulfinyl cyanide,"[$(C(=[OX1])[CX2]#[NX1]),$(S(=[OX1])[CX2]#[NX1])]",* +523,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1 +524,Hydrazine and other nucleophilic NH2-groups,"[NX3H2][#7,#8]",*[NH2] +525,Activated halo- and sulfonyl-aromatics,"c1([F,Cl,Br,I,$(C(C)=NO),$([CX2]#[NX1]),$([CX3]=[OX1]),$([CX4](F)(F)F),$([SX4](=[OX1])=[OX1]);!$([CX3](=[OX1])[OH1])])na([F,Cl,Br,I,$([SX4](=[OX1])(=[OX1])C)])a([!#7])a([!#7])a1",**1:*c(*)n*(*):*:1* +526,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O +527,Acyclic gem-dihalosubstituted carbon atom,"[C!R]([Cl,Br,I])[Cl,Br,I]",*C* +528,Imines,"[N!R]=[C,N]",*=N +529,Michael acceptors (carbonyl containing acrylonitrile derivatives),C[CX3H1]=[CX3!R](C(=[OX1])[!#1]~[!#1])[CX2]#[NX1],*~*C(=O)C(C#N)=[CH]C +530,Over halogenated rings,"a1c([F,Cl,Br,I])c([F,Cl,Br,I])ac([F,Cl,Br,I])a1",*c1*:*c(*)c(*)*1 +531,o-Quinones (1),"[CX3]1(=[!#1!#6])[CX3](=[!#1!#6])[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1",*=C1C=CC=CC1=* +532,o-Quinones (2),CC(=[!#1!#6;!R])C(=[!#1!#6;!R])C,*=C(C)C(=*)C +533,o-Quinones (4),CC(=[!#1!#6;!R])S(=[OX1])(=[OX1]),*=C(C)S(=O)=O +534,p-Quinones (1),"[#6X3]1=,:[#6X3][CX3](=[!#1!#6])[#6X3]=,:[#6X3][#6X3]1(=[!#1!#6])",*=C1C=CC(=*)C=C1 +535,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3 +536,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3 +537,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1 +538,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23 +539,Acid anhydrides and analogues,[!#1](=O)O[!#1]=O,O=*O*=O +540,Acyl halides and analogues,"[C,S](=[O,S])[F,Br,Cl,I]",**=* +541,Cyano carbonyl compounds ,N#CC(=O),N#CC=O +542,Methylendiamines (1),"[!$([C,S]=O)]N([!$([C,S]=O)])[CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*N(*)CN(*)* +543,Methylendiamines (2),"[!$([C,S]=O)][NH][CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*[NH]CN(*)* +544,Methylendiamines (3),"[!$([C,S]=O)][NH][CX4][NH][!$([C,S]=O)]",*[NH]C[NH]* +545,N-Acetoxy amines and their thio analogues,"[#7][#8][C,S]=O",NO*=O +546,α-Halogen substituted N-heterocycles,"[F,Br,Cl,I]-cn",*cn +547,Activated haloaromatics,"[F,Cl,Br,I][$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",** +548,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N +549,Benzyl ammoniums,cC[NX4+],cC[N+] +550,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O +551,Cations,"[#6+,#17+,#53+,#15+,#16+]",* +552,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N +553,Halogen-bonded heteroatoms,"[!#1&!#6][F,Cl,Br,I]",** +554,Cumulated double bonds,"[C,N]=C=[C,O,N,S]",*=C=* +555,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O +556,Singel acyclic N-N bonds,[#7]!@-N,N~N +557,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N +558,Activated double bonds (2),[!c][C!H0]=CC=O,*C=CC=O +559,Activated double bonds (3),"[C!H0]=C[S,N]=O",C=C*=O +560,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O +561,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS +562,Acetoxy group attached to the substituted aromatic ring,"C(=O)O[$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",*OC=O +563,"Oxetanes, thietanes","C1[O,S]CC1",*1CCC1 +564,Trihalomethyl ketones,"CC(=O)C([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C(C)=O +565,Phosphonates,[#6]P(=O)O[#6],COP(C)=O +566,Phosphorus containing compounds ,"NP(=[N,O,S])",*=PN +567,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +568,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O +569,"C, N, O, P and S atoms in unusual valence states","[#6!v4+0,#7!v3+0,#8!v2+0,#15!v3!v5+0,#16!v2!v4!v6+0]",* +570,Sulfurous acid esters,[!#1]OS(=O)O,*OS(O)=O +571,Heteroatom-bonded thiocarbonyls,"C(=S)[O,S,N]",*C=S +572,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS +573,Thiocarbonyls,C(=S)[!#1!H0],*C=S +574,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O +575,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F +576,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O +577,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1 +578,Double acyclic N=N and N=S bonds,"[NR0,SR0]=[NR0]",*=N +579,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1 +580,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC +581,"Iodosos, chlorosos","[Cl,I]=O",*=O +582,Acid grops,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +583,Phosphocyanates,PC#N,N#CP +584,α-Hydroxy nitriles,N#CC[OH],N#CC[OH] +585,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O +586,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO +587,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N +588,Nitrites,[!#1]ON=O,*ON=O +589,Nitroso compounds,[NX2]=O,N=O +590,"Any atoms except organogens, halogens, P, S, K, Na, Mg, Ca",[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +591,Double P=S and P=C bonds,"P=[S,#6]",*=P +592,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F +593,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +594,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1 +595,Phosphorus derivatives,[P!v5],P +596,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C +597,Carboxylic acid esters,[CX4]C(=O)O[#6][!#1],*COC(C)=O +598,"N,N-Dialkyl aniline derivatives (1)","[CX4][NX3]([CX4])c1cc([$([CX4]),$(O[CX4][CX4])])c([#7])[cH]c1",*c1cc(N(C)C)c[cH]c1N +599,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1 +600,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1 +601,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1 +602,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1 +603,"N,N-Dialkyl aniline derivatives (4)","[CX4]N([CX4])c1ccc([CX4][$([OH]),$(C=[C!H0]),$(N[CX4])])cc1",*Cc1ccc(N(C)C)cc1 +604,"N,N-Dialkyl aniline derivatives (5)","[CX4]N([C!H0])c1[cH][cH]c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH][cH]1 +605,"N,N-Dialkyl aniline derivatives (6)","[CX4]N([C!H0])c1[cH]c([CX4])c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH]c1C +606,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O +607,Five-membered heterocycles (1),"C1(=C)C(=O)[#7,#8,#15,#16]N=C1",C=C1C=N*C1=O +608,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O +609,Six-membered heterocycles,"[#7,#8,#15,#16]~C1~[#7,#8,#15,#16]~C[#7,#8,#15,#16][CX3](=[#7,#8,#15,#16])[CX3]1(=[C!H0])",*~C1C(=C)C(=*)*C~*~1 +610,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1 +611,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC +612,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH] +613,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1 +614,"1,2-Diimines, 1,2-diketones and their thio- and phospho-analogues","[#6][#6](=[#7,#8,#15,#16])[#6](=[#7,#8,#15,#16])[#6,Sv6]",*C(=*)C(=*)C +615,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21 +616,NH-Indoles,"[nH]1c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1[nH]c2ccc[cH]c2c1C +617,N-Alkyl substituted indoles,"n1([CH2])c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1c(C)c2[cH]cccc2n1[CH2] +618,Macrocycles,"[*r10,*r11,*r12,*r13,*r14,*r15,*r16,*r17,*r18,*r19,*r20,*r21,*r22,*r23,*r24,*r25,*r26,*r27,*r28,*r29,*r30]",* +619,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH] +620,N-Allophanoylamides and their thio analogues,"NC(=[O,S])NC(=[O,S])NC=[O,S]",*=CNC(=*)NC(=*)N +621,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1 +622,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21 +623,N-Phenylpyrrole derivatives,N1(c2[!#1]cccc2)C([CX4])=C[C!H0]=C1[CX4],CC1=CC=C(C)N1c1cccc*1 +624,"Quinones, quinone-(di)imines and their thio- and phospho-analogues","[#7,#8,#15,#16]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[#7,#8,#15,#16])-,:[#6]=,:[#6]1",*=C1C=CC(=*)C=C1 +625,Five-membered heterocycles (2),"[#7]=C1S[CH]=C([$([CH2]),$(c:c)])N1",*C1=[CH]SC(=N)N1 +626,Five-membered heterocycles (3),"[#7]=C1SC([$([CH2]),$(C=O)])=C([$([CH2]),$(c:c)])N1",*C1=C(*)SC(=N)N1 +627,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c +628,Acethylenes,"[CH2,CH3]C#C[CH2,CH3]",*C#C* +629,α-Halonitriles,"[F,Cl,Br,I][CX4][CX2]#[NX1]",*CC#N +630,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N +631,Benzthiozolium like compounds,"[#7,#8,#16]1-,:[#6]=,:[#6]-,:[#7+]2=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6]21",*1C=C[N+]2=**=**=C12 +632,Cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +633,Di-carbonyls,"[#1,#6][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(*)=O +634,Haloalkyl,"[C!H0]([#1,#6,#7,#8,#16])[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])[Cl,Br,I]",*CC(*)(*)* +635,"Haloalkyl group attached to S, N or O atoms","[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])([Cl,Br,I])[#7,#8,#16]",*C(*)(*)* +636,Haloethylenes,"[CX3!H0]=[CX3]([#1,Cl,Br,I])[Cl,Br,I]",*C(*)=C +637,Halopyridines,"c1([F,Cl,Br,I])n[c,n][c,n][c,n][c,n]1",*c1*:*:*:*n1 +638,Heptanes,"[CH3][CH2][CH2][CH2][CH2][CH2][CH2,CH3]",*[CH2][CH2][CH2][CH2][CH2][CH3] +639,N-Oxides (six-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1)]",* +640,N-Oxides (five-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1)]",* +641,Phosphorus cations,[#15+],[PH4+] +642,Peroxide like compounds,"O[F,Cl,Br,I]",*O +643,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O +644,Double P=O bonds,[#15]=O,O=P +645,Pyridinium like compounds,"[#6][#7+]1=,:[#6]-,:[#6,#7]=,:[#6]-,:[#6,#7]=,:[#6]1",C[N+]1=C*=C*=C1 +646,Quinolizinium like compounds,"[#6,#7]1=,:[#6,#7]-,:[#6,#7]=,:[#7+]2-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6]2=,:[#6,#7]1",*1=**=[N+]2*=**=*C2=*1 +647,Sulfates,"[Sv6X4](=[OX1])(=[OX1])([#8])[#6,#8]",*S(O)(=O)=O +648,Thio aldehydes,"[#6,#1][CX3]([H])=[SX1]",*C([H])=S +649,Thio halogens,"[#16][F,Cl,Br,I]",*S +650,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH] +651,Thiozolium like compounds,"[#6][#7+]1=,:[#6]-,:[#7,#8,#16]-,:[#6]=,:[#6]1",C[N+]1=C*C=C1 +652,Acyl Halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +653,Sulphonyl Halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +654,Alkyl Halides,"[CX4][F,Cl,Br,I]",*C +655,Activated Halides,"[$(c([F,Cl,Br,I])c[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])aac[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])n),$(c([F,Cl,Br,I])aan)]",* +656,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +657,Aldehydes (including aminoformyl moieties),"[$([#1,#6][CX3]([H])=[OX1]),$([#7]([#1,#6])([#1,#6])[CX3H1]=[OX1])]",* +658,Nitrosos,[NX2]=[OX1],N=O +659,Picrates,"c1([OH1,O-])c([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])",*c1cc(*)c(*)c(*)c1 +660,Perchlorates (periodates),"[$([Clv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-]),$([Iv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-])]",* +661,Simple anilines and phenols,"[$(c1([NX3]([#1,#6])[#1,#6])ccccc1),$(c1([OH1])ccccc1)]",* +662,Vinyl ketones (Michael acceptors),[CX3]([!R])([!R])=[CX3][CX3](=[OX1])[!$([OH1])!$([OX2][CH2])!$([NH2])!$([CX2]#[NX1])!a],*C(=O)C=C(*)* +663,Metals,[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +664,Non-organic chemistry atoms,[!#6!#1!#7!#8!#9!#17!#35!#53!#15!#14!#16],* +665,Atoms not supported in ALOGPS program,[!#1!#6!#7!#8!#16!#15!#9!#17!#35!#53],* +666,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F +667,Carbonyl compouns: aldehydes or ketones,"[$([H][CX3]([#1,#6])=[OX1]),$([#6&!$(C#N)][CX3](=[OX1])[#6&!$(C#N)])]",* +668,Thiocarbonyl compounds: thioaldehydes or thioketones,"[$([#1,#6][#6X3](=[SX1])[#1,#6]),$([#6]=[CX2]=[Sv2X1])]",* +669,Thioaldehydes,"[#1][CX3]([#1,#6])=[SX1]",*C([H])=S +670,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S +671,Hydrazones,"[CX3]([#1,#6])([#1,#6])=[NX2][#7X3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)* +672,Semicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=O)N(*)* +673,Thiosemicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=S)N(*)* +674,Oximes,"[#1,#6][CX3]([#1,#6])=[NX2][OH1]",*C(*)=N[OH] +675,Oxime ethers,"[#1,#6][CX3]([#1,#6])=[NX2][OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NOC +676,Ketene acetal derivatives,"[#1,#6][CX3]([#1,#6])=[CX3]([!#6!#1])[!#6!#1]",*C(*)=C(*)* +677,Carbonyl hydrates,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OH1]",[OH]*[OH] +678,Hemiacetals / Hemiketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*[OH] +679,Acetals / Ketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*OC +680,Hemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,*])[#1,*]",*O*N(*)* +681,Thiohemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[NX3]([#1,*])[#1,*]",*S*N(*)* +682,Thioacetals / Thioketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[SX2,OX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)]",C**SC +683,Enols,"[CX3]([#1,#6])([#1,#6])=[CX3]([OH1])[#1,#6]",*C(*)=C(*)[OH] +684,Enolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([OX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]",*C(*)=C(*)OC +685,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH] +686,Alcohols,"[$([CX4][OH1])&!$(C([OH1])[#7,#8,#15,#16,F,Cl,Br,I])]",* +687,Primary alcohols,"[$([#6][CH2][OH1]),$([CH3][OH1])]",* +688,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH] +689,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH] +690,"1,2-Diols","[CX4]([OH1])([#1,#6])([#1,#6])[CX4]([OH1])([#1,#6])([#1,#6])",*C(*)([OH])C(*)(*)[OH] +691,"1,2-Aminoalcohols","[CX4]([#1,#6])([#1,#6])([OH1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([CX4][CX4][OH1])[#6&!$([CX3]=[OX1,SX1,NX2,C])])]",*C(*)(*)C(*)(*)[OH] +692,Phenols,c[OH1],c[OH] +693,Diphenols,"[$(c([OH1])c([OH1])),$(c([OH1])[aR1]c([OH1])),$(c1([OH1])aac([OH1])aa1)]",* +694,Enediols,"[CX3]([#1,#6])([OH1])=[CX3]([#1,#6])([OH1])",*C([OH])=C(*)[OH] +695,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC +696,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc +697,Diarylethers,c[OX2&!$([OX2r3])]c,cOc +698,Hydroperoxides,"[#1,#6][OX2][OX2H1]",*O[OH] +699,Hydrazine derivatives,"[$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])][$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])]",** +700,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +701,Primary aromatic amines,[NX3H2]c,c[NH2] +702,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C +703,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C +704,Secondary aromatic amines,[NX3H1](c)c,c[NH]c +705,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C +706,Tertiary mixed amines (aryl alkyl),"c[NX3]([CX4&!$([CX4]([NX3])[O,N,S,P])])[c,CX4&!$([CX4]([NX3]c)[O,S,N,P])]",*N(c)C +707,Quaternary ammonium salts,"[NX4,NX4+]([#6])([#6])([#6])[#6]",C*(C)(C)C +708,"Halogen derivatives (alkyl, alkenyl, aryl)","[CX4,CX3,c;!$([#6]=[OX1])][F,Cl,Br,I]",** +709,Aryl fluorides,aF,*F +710,Aryl chlorides,aCl,*Cl +711,Aryl bromides,aBr,*Br +712,Aryl iodides,aI,*I +713,Organolithium compounds,[Li][#6],[Li]C +714,Organomagnesium compounds,[Mg][#6],C[Mg] +715,Carboxylic acid derivatives,"[#1,#6][CX3](=[OX1])[!#1!#6!$([SH1,SX2])]",*C(*)=O +716,Carboxylic acid salts,"[#1,#6][CX3](=[OX1])[OX1-]",*C(=O)[O-] +717,Carboxylic acid amides,"[#1,#6][CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=O)N(*)* +718,Carboxylic acid primary amides,"[#1,#6][CX3](=[OX1])[NX3H2]",*C([NH2])=O +719,Carboxylic acid secondary amides,"[#1,#6][CX3](=[OX1])[NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)[NH]C +720,Carboxylic acid tertiary amides,"[#1,#6][CX3](=[OX1])[NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)N(C)C +721,Lactams,"[#6R][CX3R](=[OX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=O +722,Carboxylic acid hydrazides,"[$([#6,#1][#6X3](=[OX1])[#7X3&!$([#7X3]([*]=[OX1,SX1])[#7X3]([*]=[OX1,SX1]))][#7X3]),$(C1(=O)[NX3][NX3]C(=O)cc1)]",* +723,Carboxylic acid azides,"[#1,#6][CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C(*)=O +724,Hydroxamic acids,"[#1,#6][CX3](=[OX1])[NX3][OH1]",*C(=O)N[OH] +725,Carboxylic acid amidines,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,N])]",*N=C(*)N(*)* +726,Carboxylic acid amidrazones,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)N(*)N(*)* +727,Nitriles,"[#1,#6&!$([CX3]=[OX1,SX1])][CX2]#[NX1]",*C#N +728,Acyl fluorides,"[#1,#6][CX3](=[OX1])F",*C(=O)F +729,Acyl chlorides,"[#1,#6][CX3](=[OX1])Cl",*C(=O)Cl +730,Acyl bromides,"[#1,#6][CX3](=[OX1])Br",*C(=O)Br +731,Acyl iodides,"[#1,#6][CX3](=[OX1])I",*C(=O)I +732,Acyl cyanides,"[#1,#6][CX3](=[OX1])[CX2]#[NX1]",*C(=O)C#N +733,Imido esters,"[#1,#6][CX3](=[NX2][#1,#6])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*N=C(*)OC +734,Thiocarboxylic acid derivatives,"[$([#1,#6][CX3](=[SX1])[!#1!#6]),$([#1,#6][CX3](=[OX1])[SX2])]",* +735,Thiocarboxylic acids,"[$([#1,#6][CX3](=[SX1])[OH1,SH1]),$([#1,#6][CX3](=[OX1])[SH1])]",* +736,Thiocarboxylic acid esters,"[$([#1,#6][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#1,#6][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +737,Thiolactones,"[$([#6R][CX3R](=[SX1])[OX2R,SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])]),$([#6R][CX3R](=[OX1])[SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])])]",* +738,Thiocarboxylic acid amides,"[#1,#6][CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=S)N(*)* +739,Thiolactams,"[#6R][CX3R](=[SX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=S +740,Imidothioesters,"[#1,#6][CX3](=[NX2][#1,#6])[SX2][C&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)SC +741,Oxohetarenes,"[$(c(=[OX1])[$(n[#1,#6]),o,s]),$(c(=[OX1])a[$(n[#1,#6]),o,s]),$(c(=[OX1])aa[$(n[#1,#6]),o,s]),$(c(=[OX1])aaa[$(n[#1,#6]),o,s])]",* +742,Thioxohetarenes,"[$(c(=[SX1])[$(n[#1,#6]),o,s]),$(c(=[SX1])a[$(n[#1,#6]),o,s]),$(c(=[SX1])aa[$(n[#1,#6]),o,s]),$(c(=[SX1])aaa[$(n[#1,#6]),o,s])]",* +743,Iminohetarenes,"[$(c(=N)[$(n[#1,#6]),o,s]),$(c(=N)a[$(n[#1,#6]),o,s]),$(c(=N)aa[$(n[#1,#6]),o,s]),$(c(=N)aaa[$(n[#1,#6]),o,s])]",* +744,Orthocarboxylic acid derivatives,"[CX4&!$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]))]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])([!#1!#6])([!#1!#6])[!#1!#6]",*C(*)(*)* +745,Carboxylic acid orthoesters,"[#1,#6][CX4]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*C(OC)(OC)OC +746,Carboxylic acid amide acetals,"[CH1,$([CX4][#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[NX3]([#1,*])[#1,*]",*N(*)*(OC)OC +747,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O +748,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O +749,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O +750,CO2 derivative (general),"[$([Cv4X4]([!#1!#6])([!#1!#6])([!#1!#6])[!#1!#6]),$([CX3](=[!#1!#6])([!#1!#6])[!#1!#6]),$([CX2](=[!#1!#6])=[!#1!#6]),$([CX2](#[!#1!#6])[!#1!#6])]",* +751,Carbonic acid derivatives,"[$([CX3](=[OX1])([!#1!#6])[!#1!#6])&!$([CX3](=[OX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +752,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH] +753,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC +754,Carbonic acid ester halides,"[#6][OX2][CX3](=[OX1])[F,Cl,Br,I]",*C(=O)OC +755,Thiocarbonic acid derivatives,"[$([CX3](=[SX1])([!#1!#6])[!#1!#6])&!$([CX3](=[SX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5]),$([CX3](=[OX1])([!#1!#6])[SX2])&!$([CX3](=[OX1])([#7,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +756,Thiocarbonic acid monoesters,"[$([OH1,SH1][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([OH1][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([SH1][CX3](=[SX1,OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +757,Thiocarbonic acid diesters,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +758,Thiocarbonic acid ester halides,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[F,Cl,Br,I]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[F,Cl,Br,I])]",* +759,Carbamic acid derivatives,"[NX3]([#1,*])([#1,*])[CX3](=[OX1])[!#1!#6!#16!$([Pv5])]",*C(=O)N(*)* +760,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH] +761,Carbamic acid esters (urethanes),"[#6][OX2][CX3](=[OX1])[NH2,NH1,NX3]",*C(=O)OC +762,Carbamic acid halides,"[F,Cl,Br,I][CX3](=[OX1])[NX3]",*C(N)=O +763,Thiocarbamic acid derivatives,"[$([NX3&!$([NX3]([CX3]=[SX1])[CX3]=[OX1,SX1,NX2])][CX3](=[SX1])[!#1!#6!#7!$([Pv5])]),$([NX3&!$([NX3]([CX3]=[OX1])[CX3]=[OX1,SX1,NX2])][CX3](=[OX1])[SH1,SX2])]",* +764,Thiocarbamic acids,"[$([OH1,SH1][CX3](=[SX1])[NX3]),$([SH1][CX3](=[OX1])[NX3])]",* +765,Thiocarbamic acid esters,"[$([#6][OX2,SX2][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])]),$([#6][SX2][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])])]",* +766,Thiocarbamic acid halides,"[F,Cl,Br,I][CX3](=[SX1])[NX3]",*C(N)=S +767,Isoureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([OX2])=[NX2][#1,#6]",*N=C(O)N(*)* +768,Isothioureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([S&!$([SX2]([CX3]=N)C=C)])=[NX2][#1,#6]",*N=C(S)N(*)* +769,Guanidines,"N[CX3](=[NX2][#1,#6])N",*N=C(N)N +770,Semicarbazides,"[$([NX3][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[OX1])[NX3]N=C)]",* +771,Thiosemicarbazides,"[$([NX3][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[SX1])[NX3]N=C)]",* +772,Isonitriles,"[#6&!$([CX3]=[OX1,SX1])][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +773,Sulfuric acid derivatives,[!#1!#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(*)(=O)=O +774,Sulfuric acid,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])[OX2,O-]",*S(*)(=O)=O +775,Sulfuric acid monoesters,"[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(=O)(=O)OC +776,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC +777,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O +778,Sulfuric acid amides,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])N",*S(N)(=O)=O +779,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O +780,Sulfuryl halides,"[!#1!#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +781,Sulfonic acid derivatives,[#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(C)(=O)=O +782,Sulfonic acids,"[#6][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(C)(=O)=O +783,Sulfonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +784,Sulfones,"[#6][Sv6X4](=[OX1,SX1,NX2])(=[OX1,SX1,NX2])[#6]",*=S(=*)(C)C +785,Sulfinic acid derivatives,[#6][Sv4X3](=[OX1])[!#1!#6],*S(C)=O +786,Sulfinic acids,"[#6][Sv4X3](=[OX1])[OH1,O-]",*S(C)=O +787,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O +788,Sulfinic acid halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +789,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O +790,Sulfenic acid derivatives,[#6][Sv2X2][!#6!#1!S],*SC +791,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH] +792,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC +793,Sulfenic acid halides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][F,Cl,Br,I]",*SC +794,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C +795,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH] +796,Thiophenols,c[Sv2H1],c[SH] +797,Phosphoric acid derivatives,"[OX1]=[Pv5X4]([H,!#6!$([SX2])])([H,!#6!$([SX2])])[H,!#6!$([SX2])]",*P(*)(*)=O +798,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH] +799,Phosphoric acid esters,[OX1]=[Pv5X4]([OX2][#6])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(=O)OC +800,Phosphoric acid halides,"[OX1]=[Pv5X4]([F,Cl,Br,I])([!#6!$([SX2])])[!#6!$([SX2])]",*P(*)(*)=O +801,Phosphoric acid amides,[OX1]=[Pv5X4]([NX3])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(N)=O +802,Thiophosphoric acid derivatives,"[$([SX1]=[Pv5X4]([H,!#6])([H,!#6])[H,!#6]),$([OX1]=[Pv5X4]([SX2])([H,!#6])[H,!#6])]",* +803,Thiophosphoric acids,"[$([SX1]=[Pv5X4]([OH1,SH1])([O,S])[O,S]),$([OX1]=[Pv5X4]([SH1])([O,S])[O,S])]",* +804,Thiophosphoric acid esters,"[$([SX1]=[Pv5X4]([OX2,SX2][#6])([!#6])[!#6]),$([OX1]=[Pv5X4]([SX2][#6])([!#6])[!#6])]",* +805,Thiophosphoric acid halides,"[$([SX1]=[Pv5X4]([F,Cl,Br,I])([!#6])[!#6]),$([OX1]=[Pv5X4]([F,Cl,Br,I])([SX2,SH1])[!#6])]",* +806,Thiophosphoric acid amides,"[$([SX1]=[Pv5X4]([NX3])([!#6])[!#6]),$([OX1]=[Pv5X4]([NX3])([SX2,SH1])[!#6])]",* +807,Phosphonic acid derivatives,[OX1]=[Pv5X4]([#6])([!#6])[!#6],*P(*)(C)=O +808,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH] +809,Phosphonic acid esters,[OX1]=[Pv5X4]([#6])([OX2][#6])[!#6],*P(C)(=O)OC +810,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C +811,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O +812,Boronic acid derivatives,[Bv3X3]([#6])([!#6])[!#6],*B(*)C +813,Boronic acids,"[BX3]([#6])([OH1,SH1])[O,S]",*B(*)C +814,Boronic acid esters,"[BX3]([#6])([OX2][#6])[H,!#6]",*B(C)OC +815,Aromatic compounds,[a!r0],* +816,Heterocyclic compounds,[*R]~[*R&!#6]~[*R],*~*~* +817,Aromatic heterocyclic compounds,[a!#6!r0],* +818,α-Aminoacids,"[OH1][CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([#6])[#6])&!$([NH1](CC(=O)[OH1])[CX3]=[OX1,SX1])]",*C(*)(*)C(=O)[OH] +819,α-Hydroxyacids,"[OH1][CX3](=[OX1])[CX4]([OH1])[#1,#6]",*C([OH])C(=O)[OH] +820,"1,2-Diamines","[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])[CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CCN(*)* +821,"1,2-Dithiols","[CX4]([SH1])([#1,#6])([#1,#6])[CX4]([SH1])([#1,#6])([#1,#6])",*C(*)([SH])C(*)(*)[SH] +822,"1,2-Aminothiols","[SH1][CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CC[SH] +823,α-Oxoacids,"[OH1][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(=O)[OH] +824,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH] +825,Dithiophenols,"[$(c([SH1])c([SH1])),$(c([SH1])[aR1]c([SH1])),$(c1([SH1])aac([SH1])aa1)]",* +826,Aminothiophenols,"[$(c([SH1])c[NX3]([#1,#6])[#1,#6]),$(c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]),$(c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1)]",* +827,Aryl halides,"a[F,Cl,Br,I]",** +828,Primary amines,"[NX3H2][c,CX4&!$([CX4]([NH2])[O,N,S,P])]",*[NH2] +829,Secondary amines,"[NX3H1]([c,CX4&!$([CX4]([NX3H1])[O,S,N,P])])[c,CX4&!$([CX4]([NX3H1])[O,S,N,P])]",*[NH]* +830,Tertiary amines,"[NX3]([c,CX4&!$([CX4]([NX3])[O,S,N,P])])([c,CX4&!$([CX4]([NX3])[O,S,N,P])])[c,CX4&!$([CX4]([NX3])[O,S,N,P])]",*N(*)* +831,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C +832,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C +833,Alkynyl halides,"[F,Cl,Br,I][CX2]#[CX2]",*C#C +834,Benzyl halides,"a[CX4][F,Cl,Br,I]",*C* +835,Benzyl fluorides,a[CX4]F,*CF +836,Benzyl chlorides,a[CX4]Cl,*CCl +837,Benzyl bromides,a[CX4]Br,*CBr +838,Benzyl iodides,a[CX4]I,*CI +839,Alkali metals,"[#3,#11,#19,#37,#55,#87]",* +840,Alkaline earth metals,"[#4,#12,#20,#38,#56,#88]",* +841,Transition metals,"[#21,#22,#23,#24,#25,#26,#27,#28,#29,#30,#39,#40,#41,#42,#43,#44,#45,#46,#47,#48,#72,#73,#74,#75,#76,#77,#78,#79,#80,#104,#105,#106,#107,#108,#109,#110,#111,#112]",* +842,Lanthanoids,"[#57,#58,#59,#60,#61,#62,#63,#64,#65,#66,#67,#68,#69,#70,#71]",* +843,Actinoids,"[#89,#90,#91,#92,#93,#94,#95,#96,#97,#98,#99,#100,#101,#102,#103]",* +844,Post-transition metals,"[#13,#31,#49,#50,#81,#82,#83,#113,#114,#115,#116]",* +845,Metalloids,"[#5,#14,#32,#33,#51,#52,#84]",* +846,Nonmetals,"[#1,#6,#7,#8,#15,#16,#34,#9,#17,#35,#53,#85,#117,#2,#10,#18,#36,#54,#86,#118]",* +847,Halogens,"[#9,#17,#35,#53,#85,#117]",* +848,Noble gases,"[#2,#10,#18,#36,#54,#86,#118]",* +849,Chalcogens (oxygen group),"[#8,#16,#34,#52,#84,#116]",* +850,Pnictogens (nitrogen group),"[#7,#15,#33,#51,#83]",* +851,Tetragens (carbon group),"[#6,#14,#32,#50,#8,#114]",* +852,Thioenolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([SX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]",*C(*)=C(*)SC +853,Thioenols,"[CX3]([#1,#6])([#1,#6])=[CX3]([SH1])[#1,#6]",*C(*)=C(*)[SH] +854,Enethiodiols,"[CX3]([#1,#6])([SH1])=[CX3]([#1,#6])([SH1])",*C([SH])=C(*)[SH] +855,Alkynyl alcohols,[CX2]#[CX2][OH1],C#C[OH] +856,Alkynyl thiols,[CX2]#[CX2][SH1],C#C[SH] +857,Thioquinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[SX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1,SX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]",* +858,4halo_pyrimidine_2_6EWG,"n1c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[n;R1]c([F,Cl,Br,I])cc1([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])",*c1cc(*)nc(*)n1 +859,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O,NC(COP(O)(O)=O)C(O)=O +860,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O,CC(OP(O)(O)=O)C(N)C(O)=O +861,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O +862,sulphonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O +863,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S,O=C(S)C(F)(F)F +864,2halo_pyrazine_5EWG,"[n;R1]1c([F,Cl,Br,I])[c;!$(c-N)]nc([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[c;!$(c-N)]1",*c1cnc(*)cn1 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+873,4halo_pyrimidine_5EWG,"n1c[n;R1]c([F,Cl,Br,I])[#6]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])c1",*C1cncnc1* +874,alpha_halo_EWG,"[$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-])]-[CH,CH2]-[Cl,Br,I,$(O(S(=O)(=O)))]",*** +875,2halo_pyrazine_3EWG,"[n;R1]1c([F,Cl,Br,I])c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])ncc1",*c1nccnc1* +876,boron_warhead,"[C,c]~[#5]",*~B +877,diamino_sulfide,"[N,n]~[S;!R;D2]~[N,n]",*~S~* +878,dicarbonyl_sulfonamide,"[$(N(-C(=O))(-C(=O))(-S(=O))),$(n([#6](=O))([#6](=O))([#16](=O)))]",* +879,acyl_imidazole,"[C;!$(C-N)](=O)n1[c;H1,$([#6]([*;!R]))]n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1ccnc1 +880,halo_phenolic_sulfonyl,"S(=O)Oc1c([Cl,F])[cH1,$(c[F,Cl])]c([F,Cl])[cH1,$(c[F,Cl])]c1([F,Cl])",*c1*c(*)c(OS=O)c(*)*1 +881,oxaziridine,"C1~[O,S]~N1",*1~CN~1 +882,sulf_D3_nitrogen,"[S;D3](-N)(-[c,C])(-[c,C])",*[SH](*)N 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+1093,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1 +1094,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1 +1095,Thio_dibenzo,"[SX1]=[#6]1-,:[#6]=,:[#6]-,:[!#1!#6]-,:[#6]=,:[#6]1",S=C1C=C*C=C1 +1096,Het_65_A,"[OX1]=CC1=C2N=C([CH2,CH3])C=C([OH1])N2N=C1",*C1=NC2=C(C=O)C=NN2C([OH])=C1 +1097,Het_6_tetrazine,"N~c1[n,$(c(N))][n,c!H0,$(c[N!H0])]c([N!H0,$([OX2][CH2,CH3])])nn1",*c1*:*c(~N)nn1 +1098,Imidazole_A,"[#7]1-,:[#6](-c2ccccc2)=,:[#6](-c3ccccc3)-,:[#7!H0]-,:[#6]1-ca",*cC1NC(c2ccccc2)=C(c2ccccc2)N1 +1099,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH] +1100,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1101,Anisol_A,"c1(O[CH2,CH3])c([H,CH2,CH3])[cH]c(O[CH2,CH3])c([CH2][$([N!H0]C(=[OX1])[CH2][CH2][CH2,CH3]),$([C!H0]([CH2,CH3])[N!H0]C(=[SX1])[N!H0])])[cH]1",*[CH2]c1[cH]c(O*)c(*)[cH]c1O* +1102,Anisol_B,"[CH2,CH3](c4c([cH][cH]c([cH]4)[CH2][N!H0][CX4])O[CH2,CH3])",*Oc1[cH][cH]c([CH2]NC)[cH]c1* +1103,Anthranil_acid_B,"c3cc(C(=[OX1])[N!H0]c4ccccc4C(=[OX1])[OH1])cc1c3C(=[OX1])N([CH2,CH3])C1=[OX1]",*N1C(=O)c2ccc(C(=O)Nc3ccccc3C(=O)[OH])cc2C1=O +1104,Anthranil_acid_C,"[#6]1(=,:[#6]([NH2])-,:[#7](-c7ccccc7C(=[OX1])[OH1])-,:[#7]=,:[#6]1C=[OX1])[$(C#[NX1]),$(C=S)]",*C1=C([NH2])N(c2ccccc2C(=O)[OH])N=C1C=O +1105,Anthranil_acid_D,"c12ncccc1-,:[#6]([NH2])=,:[#6](C(=[OX1])~[OX1,O-])-,:[#16]2",*~C(=O)C1=C([NH2])c2cccnc2S1 +1106,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH] +1107,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH] +1108,Anthranil_acid_G,"c1([cH][cH]c(O[CH2,CH3])[cH]c1(C(=[OX1])[OH1]))[N!H0]cc",*Oc1[cH][cH]c(Ncc)c(C(=O)[OH])[cH]1 +1109,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1 +1110,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1 +1111,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH] +1112,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1 +1113,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1 +1114,Anil_alk_A,"[CH2,CH3]Occ[CH2][N!H0]c1[cH]c2n[cH]n([#6!H0])c2[cH][cH]1",*Occ[CH2]Nc1[cH][cH]c2c([cH]1)n[cH]n2C +1115,Anil_alk_B,"[N!H0](c1[cH][cH]c([CH2,CH3])[cH][cH]1)[CH2][CH2]c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c([CH2][CH2]Nc2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1116,Anil_alk_C,"[N!H0](c1ccccc1)C([#6])([#6])c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c(C(C)(C)Nc2ccccc2)[cH][cH]1 +1117,Anil_alk_D,"[N!H0](c1[cH][cH]c([C!H0]([CH2,CH3])[CH2,CH3])[cH][cH]1)[CH2][CH2]N([CH2,CH3])[CH2,CH3]",*C(*)c1[cH][cH]c(N[CH2][CH2]N(*)*)[cH][cH]1 +1118,Anil_alk_thio,c1ccc2c(c1)C3=C(C([#6])([#6])N2)SSC3=*,*=C1SSC2=C1c1ccccc1NC2(C)C +1119,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2 +1120,Anil_di_alk_F,"c1c(ccc(N([H,CX4])([H,CX4]))c1)[CX4]c2ccc(cc2)N([H,CX4])([H,CX4])",*N(*)c1ccc(Cc2ccc(N(*)*)cc2)cc1 +1121,Anil_di_alk_J,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6!H0]=[#7][#7]=[#6]([#6])-cc)[cH][cH]1",*N(*)c1[cH][cH]c(C=NN=C(C)cc)[cH][cH]1 +1122,Anil_di_alk_I,"[cH]1c([N!H0]C(=[OX1])c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=O)c2ccccc2)[cH]1 +1123,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1 +1124,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12 +1125,Anil_di_alk_ene_B,"[CH2,CH3]N([CH2,CH3])C1=Cc2ccccc2[CH2]1",*N(*)C1=Cc2ccccc2[CH2]1 +1126,Anil_di_alk_furan_B,"[CH2,CH3]N([CH2,CH3])c1[cH][cH]c(o1)[C!H0]=CC#[NX1]",*N(*)c1[cH][cH]c(C=CC#N)o1 +1127,Anil_di_alk_indol,"c12[cH][cH]c(N([CH2,CH3])[CH2,CH3])[cH]c1-,:[#6](S(=[OX1])=[OX1])=,:[#6H]-,:[#7!H0]2",*N(*)c1[cH][cH]c2c([cH]1)C(S(=O)=O)=[CH]N2 +1128,Anil_no_alk_indol_A,"c12[cH][cH]c([NH2])[cH]c1[cH][cH]n2[CH2,CH3]",*n1[cH][cH]c2[cH]c([NH2])[cH][cH]c21 +1129,Anil_NH_alk_A,"c1([N!H0][CH2,CH3])[cH][cH]c2c([cH]1)[#7!H0]-,:[#6](=[OX1])-,:[#7!H0]2",*Nc1[cH][cH]c2c([cH]1)NC(=O)N2 +1130,Anil_NH_alk_B,[N!H0](c1ccacc1)c2ccc([N!H0][C!H0])cc2,CNc1ccc(Nc2cc*cc2)cc1 +1131,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC +1132,Anil_NH_alk_D,"[NH2]c1c([N!H0][C!H0]([#6])[C!H0][CH2,CH3])c[cH][cH][cH]1",*CC(C)Nc1c[cH][cH][cH]c1[NH2] +1133,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1 +1134,Anil_NH_no_alk_B,"[NH2]c1c([N!H0]S(=[OX1])=[OX1])[cH]c([N!H0][CH2,CH3])c([F,Cl,Br,I])[cH]1",*Nc1[cH]c(NS(=O)=O)c([NH2])[cH]c1* +1135,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1 +1136,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH] +1137,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12 +1138,Anil_OC_alk_A,"[cH]1[cH][cH]c2c([cH]1)c3c(o2)[cH]c([N!H0][CH2,CH3])c(O[CH2,CH3])[cH]3",*Nc1[cH]c2oc3[cH][cH][cH][cH]c3c2[cH]c1O* +1139,Anil_OC_alk_B,"c2ccccc2N1C(=[OX1])C([N!H0]c2ccc(O[CH2,CH3])cc2)=C([F,Cl,Br,I])C1=[OX1]",*Oc1ccc(NC2=C(*)C(=O)N(c3ccccc3)C2=O)cc1 +1140,Anil_OC_alk_C,"[H,CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2]c2nccn2",*Oc1[cH][cH][cH][cH]c1N[CH2]c1nccn1 +1141,Anil_OC_alk_D,"[CH2,CH3]Oc1[cH][cH]c([CH2,CH3])[cH]c1[NH][CH2]c2c([CH2,CH3,$(O[CH2,CH3])])cccc2",*Oc1[cH][cH]c(*)[cH]c1[NH][CH2]c1ccccc1* +1142,Anil_OC_alk_E,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2][C!H0]([OH1])[CH2,CH3]",*Oc1[cH][cH][cH][cH]c1N[CH2]C(*)[OH] +1143,Anil_OC_alk_F,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][C!H0]([#16])C=[OX1]",*Oc1[cH][cH][cH][cH]c1NC(S)C=O +1144,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1 +1145,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2] +1146,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1 +1147,Anil_no_alk_B,"[NH2]c1c(n2cccc2)[cH]c([CH2,CH3])c([CH2,CH3])[cH]1",*c1[cH]c([NH2])c(n2cccc2)[cH]c1* +1148,Anil_no_alk_D,"n1c([NH2])c([CH2,CH3])[cH]c([CH2,CH3])c1[NH2]",*c1[cH]c(*)c([NH2])nc1[NH2] +1149,Anil_no_alk_C,"[NH2]c1[cH][cH]c([cH][cH]1)-c2[cH]c(C=[OX1])c([CH2,CH3])o2",*c1oc(-c2[cH][cH]c([NH2])[cH][cH]2)[cH]c1C=O +1150,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12 +1151,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1 +1152,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12 +1153,Hzone_acyl_misc_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C(=[OX1])[N!H0]N=C([H,CH2,CH3])c2cc(*-*-*c3occc3)ccc2",*C(=NNC(=O)c1[cH][cH]c(*)o1)c1cccc(***c2ccco2)c1 +1154,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1 +1155,Hzone_thiophene_A,"[cH]2[cH][cH][cH]c1c2c([C!H0]=N[N!H0]([$(c3nc[cH]s3),$(c[cH][cH]),$(cncncn),$(cnnnn)]))c([H,$([OH1]),CH2,CH3])[a!c]1",*NN=Cc1c(*)*c2[cH][cH][cH][cH]c12 +1156,Hzone_thiophene_B,"c1(s[cH][cH]c1[H,CH2,CH3])[C!H0]=N[N!H0]c2ccccc2",*c1[cH][cH]sc1C=NNc1ccccc1 +1157,Hzone_phenone,"C(c1[cH]cc([H,CX4])[cH][cH]1)(c2[cH][cH]c([H,Cl])[cH][cH]2)=[$(NO[CH2][CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(NO[CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(N[N!H0]C(=[NH1])[NH2]),$([#6!H0][#7])]",*c1c[cH]c(C(=*)c2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1158,Hzone_furan_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[N!H0]c2nccs2",*C(=NNc1nccs1)c1[cH][cH]c(*)o1 +1159,Hzone_furan_B,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[NH]c2ccncc2",*C(=N[NH]c1ccncc1)c1[cH][cH]c(*)o1 +1160,Hzone_furan_C,c1ccccc1N(c2ccccc2)N=[C!H0]c3ac([cH][cH]3)-c4cc(C(=[OX1])[OH1])ccc4,O=C([OH])c1cccc(-c2*c(C=NN(c3ccccc3)c3ccccc3)[cH][cH]2)c1 +1161,Hzone_furan_E,[OH1]C(=[OX1])c1cc(ccc1)-cacC=N[N!H0]C(=[OX1])[CH2][#8],O[CH2]C(=O)NN=Cc*c-c1cccc(C(=O)[OH])c1 +1162,Hzone_naphth_A,"[cH]1[cH][cH]c2[cH][cH]c(C=N[N!H0][$(cc),$(C=[SX1])])[cH]c2c1",*NN=Cc1[cH][cH]c2[cH][cH][cH]cc2[cH]1 +1163,Hzone_acid_A,"[cH]1[cH]c(O[CH2,CH3])[cH]c2C(=N[N!H0]c4[cH][cH]c(C(=[OX1])[OH1])[cH][cH]4)c3[cH]c(O[CH2,CH3])[cH][cH]c3c12",*Oc1[cH][cH]c2c([cH]1)C(=NNc1[cH][cH]c(C(=O)[OH])[cH][cH]1)c1[cH]c(O*)[cH][cH]c12 +1164,Hzone_acid_D,[OH1]C(=[OX1])c1ccc(cc1)NN=[C!H0]c2ac([cH][cH]2)-c3ccccc3,O=C([OH])c1ccc(NN=Cc2*c(-c3ccccc3)[cH][cH]2)cc1 +1165,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1 +1166,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1 +1167,Het_5_C,"N1=C(c2ccccc2)[CH2]C([OH1])([CX4](F)(F)F)N1[$(cccccc),$(C(=S)cccccc)]",*N1N=C(c2ccccc2)[CH2]C1([OH])C(F)(F)F +1168,Het_5_D,"N1(c2ccccc2)N=C([CH2,CH3])[C!H0](S[#6])C1=[OX1]",*C1=NN(c2ccccc2)C(=O)C1SC +1169,Het_5_E,"N1(c2cccc3ccccc23)N=C([CH2,CH3])[CH2]C1=[OX1]",*C1=NN(c2cccc3ccccc23)C(=O)[CH2]1 +1170,Het_5_ene,"C1(=[OX1])C(=C([CH2,CH3])[N!H0][CH2][CH2][CH2,CH3])N=C(c2ccccc2)O1",*[CH2][CH2]NC(*)=C1N=C(c2ccccc2)OC1=O +1171,Het_5_inium,"[#7]1(c2ccccc2)[#6!H0]=[#7+,#7v4](c3ccccc3)[#6](=Nc4ccccc4)N1",C1=*(c2ccccc2)C(=Nc2ccccc2)NN1c1ccccc1 +1172,Het_5_pyrazole_OH,"n1(c2[cH][cH][cH][cH][cH]2)nc([CX4])c([H,C!H0])c1[OH1]",*c1c(C)nn(c2[cH][cH][cH][cH][cH]2)c1[OH] +1173,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1 +1174,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1 +1175,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1 +1176,Het_6_pyridone_NH2,[OH1]c2nc([NH2])acc2[CH2]C(=[OX1])[#8],[NH2]c1*cc([CH2]C(O)=O)c([OH])n1 +1177,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1 +1178,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2 +1179,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1 +1180,Het_65_B,a1a3a(aaa1)[N!H0]N(C3=O)[#6],CN1N*2:*:*:*:*:*:2C1=O +1181,Het_65_C,"C1=CC=CC2=NC([$(C([!#1])=[C!H0]cc),$(coc)])=C(Ncc)N12",*C1=C(Ncc)N2C=CC=CC2=N1 +1182,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1183,Het_65_F,"[#16]1-,:[#6]2:[#6](-,:[#6]([CH2,CH3])=,:[#6]1[CH2,CH3])c(ncn2)NN=C[#6]3=,:[#6]-,:[#6]=,:[#6]-,:[#8]3",*C1=C(*)C2:C(ncnc2NN=CC2=CC=CO2)S1 +1184,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1 +1185,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1 +1186,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12 +1187,Het_65_J,"o1c([#6](~[#8])~[#8])cc2[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c12",*Oc1[cH]c2cc(C(~O)~O)oc2[cH]c1O* +1188,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1 +1189,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O +1190,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12 +1191,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21 +1192,Het_65_pyridone_A,"c1([CH2][CH2,CH3])c([CH2,CH3])c2C(=[!#1!#6X1])N([C!H0][$(C(=O)O),$(cc)])C([H,$(S(C)[CH2,CH3])])=Nc2[a&!c;X2]1",*CN1C(=*)c2c(*c([CH2]*)c2*)N=C1* +1193,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1 +1194,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1 +1195,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1 +1196,Het_66_B,"c1ccc4c(c1)nc(nc4)[N!H0]C2=NC(C=C[N!H0]2)([CH2,CH3])[CH2,CH3]",*C1(*)C=CNC(Nc2ncc3ccccc3n2)=N1 +1197,Het_66_C,c1ccc2nc([C!H0]=C([OH1])[#6])c([C!H0]=C([OH1])[#6])nc2a1,CC([OH])=Cc1nc2*cccc2nc1C=C(C)[OH] +1198,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc +1199,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1 +1200,Het_66_anisole,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0]c2c3c(O[CH2,CH3])ccc(O[CH2,CH3])c3ncc2",*Oc1[cH][cH][cH][cH]c1Nc1ccnc2c(O*)ccc(O*)c12 +1201,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1 +1202,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3 +1203,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21 +1204,Het_565_indole,"[#6!H0]1=,:[#6!H0]-,:[#7]([CH2,CH3])c7c1c9[#6!H0]=,:[#6!H0]-,:[#7](c9c(c7O[CH2,CH3])O[CH2,CH3])[CH2,CH3]",*Oc1c(O*)c2c(c3c1N(*)C=C3)C=CN2* +1205,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21 +1206,Het_666_B,"c1cccc9c1Oc2c(N9[CH2][CH2,CH3])cccc2",*[CH2]N1c2ccccc2Oc2ccccc21 +1207,Het_666_C,"c13cc2ccccc2cc1-,:[#7]([CH2,CH3])-,:[#6](=[OX1])-,:[#6](-cc[N!H0][CH2,CH3])=,:[#7]3",*NccC1=Nc2cc3ccccc3cc2N(*)C1=O +1208,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12 +1209,Het_pyridiniums_B,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:*2=,:[#6]1-,:*=,:[#7+,#7v4](~cc)-,:*=,:[#6]2[H,*]",*C1=**(~cc)=*C2=*1C=CC=C2 +1210,Het_pyridiniums_C,"[#6]1~[#6]~[#6]~[#7+,#7v4]2~[#6](~[#7]1)~[#6]3~[#6]~[#6]~[#6]~[#7](-cc)~[#6]3~[#7]2",ccN1~C~C~C~C2C~1~N*1~C~C~CN~C~1~2 +1211,Het_thio_5_A,"[CH2,CH3][SX2]c1n(-!@[CH2,CH3])c(-c2ccccc2)[cH]n1",*Sc1n[cH]c(-c2ccccc2)n1* +1212,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1 +1213,Het_thio_5_C,"[SX1]=[#6]1-,:[#7!H0]-,:[#7]=,:[#6](c2[cH][cH]c(O[CH2,CH3])[cH][cH]2)-,:[#8]1",*Oc1[cH][cH]c(C2=NNC(=S)O2)[cH][cH]1 +1214,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1 +1215,Het_thio_5_imine_B,"N1([CH2,CH3])C(=S)N(-cc)C(=N-cc)C1=N-cc",*N1C(=S)N(cc)C(=Ncc)C1=Ncc +1216,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc +1217,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1 +1218,Het_thio_6_furan,"[CH2,CH3][SX2]c1nc(-c2o[cH][cH][cH]2)c(-c3o[cH][cH][cH]3)nn1",*Sc1nnc(-c2[cH][cH][cH]o2)c(-c2[cH][cH][cH]o2)n1 +1219,Het_thio_65_A,"[#7]1=,:[#6]([SX2][CH2,CH3])-,:[#7]=,:[#7]-,:[#6]2=,:[#6]1-,:[#6]([CH2,CH3])=,:[#7]-,:[#7]2-c3cccccc3",*SC1=NC2=C(N=N1)N(c1cccccc1)N=C2* +1220,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1 +1221,Het_thio_65_C,"n1c2ccccc2n([CH2,CH3])c1S[CH2]C(=[OX1])[N!H0]N=[C!H0][C!H0]=[C!H0]",*n1c(S[CH2]C(=O)NN=CC=C)nc2ccccc21 +1222,Het_thio_65_D,"c1(S[CH2]C(=[OX1])[NH]-cc)nc2[cH]c([F,Cl,Br,I])c[cH]c2[nH]1",*c1c[cH]c2[nH]c(S[CH2]C(=O)[NH]cc)nc2[cH]1 +1223,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1 +1224,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1 +1225,Het_thio_67_A,"[CH2,CH3][SX2]c1nc2OC=Ncc-c2nn1",*Sc1nnc2c(n1)OC=Ncc-2 +1226,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21 +1227,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12 +1228,Het_thio_656c,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]2-,:[#7+,#7v4]=,:[#6]3-,:[#7](N=C(c5ccccc5)[CX4]S3)-,:[#6]12",*1=C2SCC(c3ccccc3)=NN2C2C=CC=CC12 +1229,Het_thio_665,"c1ccc7c(c1)NC3=C(S7)SC(=C3)[CH2,CH3]",*C1=CC2=C(S1)Sc1ccccc1N2 +1230,Het_thio_666_A,"[cH]1[cH][cH][cH]c5N([H,CH3,$([CH2][C!H0])])c7c(~[H,$([N!H0][CX4]),$(cc)])c(~[H,$(cc)])c([H,NH2,$([OX2][CX4])])[cH]c7Sc15",*~c1c(~*)c2c([cH]c1*)Sc1[cH][cH][cH][cH]c1N2* +1231,Het_thio_676_A,"c1ccc4c(c1)Sc8[cH][cH]c([cH]c8C(C4)N([H,CX4])([H,CX4]))[H,#8,#16X2,CX4,$(N([H,CX4])[H,CX4])]",*c1[cH][cH]c2c([cH]1)C(N(*)*)Cc1ccccc1S2 +1232,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21 +1233,Het_thio_pyr_A,"n1c(S[C!H0])c(C#[NX1])c(c2ccc(O[Ch2,CH3])cc2)[cH]c1(cc)",*Oc1ccc(c2[cH]c(cc)nc(SC)c2C#N)cc1 +1234,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1 +1235,Het_thio_N_5B,"[#6]1~[#6](~[#7]~[#7]~[#6](~[CH2,CH3])~[CH2,CH3])~[#7]~[#16]~[#6]1",*~C(~*)~N~N~C1~CC~S~N~1 +1236,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1 +1237,Het_thio_N_55,[C!H0]c1nn(c3ccccc3)s2[a!c]acc12,Cc1nn(c2ccccc2)s2*:*cc12 +1238,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2 +1239,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc +1240,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1 +1241,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21 +1242,Styrene_B,"c1ccc4c(c1)[SX2,CX4]c8ccc(cc8C4=CC)[H,Cl,CX4]",*c1ccc2c(c1)C(=CC)c1ccccc1*2 +1243,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2 +1244,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21 +1245,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc +1246,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21 +1247,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN +1248,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S +1249,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N +1250,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1 +1251,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1 +1252,Ene_five_het_G,"C1(=[OX1])C(=[C!H0][$(c2ccccc2),$(c2ccc[a!c]2)])N=C(aaa)[#16,$(Naa)]1",*C=C1N=C(*:*:*)*C1=O +1253,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S +1254,Ene_five_het_I,c1(ccco1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2,O=C1C(=Cc2ccco2)*c2ccccc21 +1255,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S +1256,Ene_five_het_K,"[#7]1([#6])-,:[#6H]=,:[#6H]-,:[#6H]=,:[#6]1([CH]=C2C(=[OX1])[!#6]C=,:*2)",CN1[CH]=[CH][CH]=C1[CH]=C1*=C*C1=O +1257,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1 +1258,Ene_five_het_M,"C1=,:C[O,S]C(=CC=[OX1])C1=[OX1]",O=CC=C1*C=CC1=O +1259,Ene_five_het_N,"C1(=[OX1])C(=[C!H0]c2cc([F,Cl,Br,I])ccc2O[CH2,CH3])N=C(S[CH2,CH3])S1",*Oc1ccc(*)cc1C=C1N=C(S*)SC1=O +1260,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1 +1261,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O +1262,Ene_six_het_D,[OX1]=C1NNC(aa)=NC1=[C!H0],*:*C1=NC(=C)C(=O)NN1 +1263,Ene_quin_methide,"aaC([H,$(C#[NX1])])=[#6]1-,:[#6]=,:[#6]-,:[#6](=[OX1,N!R])-,:[#6]=,:[#6]1",*C(*:*)=C1C=CC(=*)C=C1 +1264,Ene_rhod_C,"S1C(=Ncc)N([H,$([CH2][CH2]O),$(cc)])C(=[OX1])C1(=[C!H0][$(cccCl),$(c[a!c])])",*C=C1SC(=Ncc)N(*)C1=O +1265,Ene_rhod_D,"S1C(=!@N[H,$([N!H0](N)cc)])N([H,$(cnccs)])C(=[OX1])C1=[C!H0]cc[Cl,$(O[C!H0])]",*ccC=C1SC(=N*)N(*)C1=O +1266,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S +1267,Ene_rhod_F,"n1ccc([C!H0]=C2C(=[OX1])NC(=[!#1!#6])N2)c1[CH2,CH3]",*c1nccc1C=C1NC(=*)NC1=O +1268,Ene_rhod_G,[OH1][CX3](=[OX1])c1cccc(c1)cac[C!H0]=C2C(=[!#1!#6])NC(=[!#1!#6])[!#1!#6]2,*=C1*C(=Cc*cc2cccc(C(=O)[OH])c2)C(=*)N1 +1269,Ene_rhod_H,"N1=C([CH2,CH3])C(=[OX1])N=C2N1C(=[OX1])C(=[C!H0]cc)S2",*C1=NN2C(=O)C(=Ccc)SC2=NC1=O +1270,Ene_rhod_I,"N1([CH2,CH3])C(=S)[N!H0]C(=[C!H0]c2cc(Br)ccc2)C1(=O)",*N1C(=O)C(=Cc2cccc(Br)c2)NC1=S +1271,Ene_rhod_J,"[CH2,CH3]N1C(=[#16,#7])[!#6]C(=[#6]2-,:[#6H]=,:[#6H]cc-,:[#7]2[CH2,CH3])C1=[OX1]",*N1cc[CH]=[CH]C1=C1*C(=*)N(*)C1=O +1272,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1 +1273,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O +1274,Ene_misc_C,"c1ccc4c(c1)N(C(C=C4)([CH2,CH3])[CH2,CH3])C(=[OX1])[N!H0]c3ccc(c(c3)O[CH2,CH3])O[CH2,CH3]",*Oc1ccc(NC(=O)N2c3ccccc3C=CC2(*)*)cc1O* +1275,Ene_misc_D,"c12[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c1C([#6])=C([#6])S[CH2]2",*Oc1[cH]c2c([cH]c1O*)C(C)=C(C)S[CH2]2 +1276,Ene_misc_E,"c1(O[CH2,CH3])c(O[CH2,CH3])[cH]c2C=C[C!H0]Sc2[cH]1",*Oc1[cH]c2c([cH]c1O*)SCC=C2 +1277,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1 +1278,Dhp_amino_CN_A,"[NH2]C1=C(C#[NX1])[C!H0](cc)C([CH2,CH3])=C(C=C)O1",*C1=C(C=C)OC([NH2])=C(C#N)C1cc +1279,Dhp_amino_CN_B,"[NX3H2,OX2H1]C1=C(C#[NX1])[C!H0](cc)c2c(n(C)nc2)O1",*C1=C(C#N)C(cc)c2cnn(C)c2O1 +1280,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N +1281,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21 +1282,Dhp_amino_CN_E,"[CH2,CH3][SX2]C1=C(C#[NX1])[C!H0](cc)C(C#[NX1])C(=O)N1",*SC1=C(C#N)C(cc)C(C#N)C(=O)N1 +1283,Dhp_amino_CN_F,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](c2cccs2)-,:[#6](C(=[OX1])O[#6])=,:[#6]([CH2,CH3])-,:[#8]1",*C1=C(C(=O)OC)C(c2cccs2)C(C#N)=C([NH2])O1 +1284,Dhp_amino_CN_G,"[SX2]1C=C(C#[NX1])C([#6])(C=[OX1])C([$(C=[OX1]),$(C#[NX1])])=C1[NH2]",*C1=C([NH2])SC=C(C#N)C1(C)C=O +1285,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N +1286,Dhp_keto_A,"[#7]1([H,CX4])-,:[#6]=,:[#6](C(=[OX1])ccc)-,:[#6]([#6])-,:[#6]([$(C=[OX1]),$(C#[NX1])])=,:[#6]1[CH3]",*C1=C([CH3])N(*)C=C(C(=O)ccc)C1C +1287,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2] +1288,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1 +1289,Сyano_keto_A,"[CH2,CH3][C!H0](C#[NX1])C(=[OX1])[#6]",*C(C#N)C(C)=O +1290,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N +1291,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N +1292,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc +1293,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O +1294,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O +1295,Cyano_pyridone_C,"C1(C([CH2,CH3])=C(C#[NX1])C(~[#8])~[#7]~[#6]1(~[#8]))=[C!H0]cc",*C1=C(C#N)C(~O)~N~C(~O)C1=Ccc +1296,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O +1297,Cyano_pyridone_E,"ac[#6]1=,:[#6!H0]-,:[#6](co)=,:[#6](C#[NX1])-,:[#6](=[OX1])-,:[#7!H0]1",*cC1=CC(co)=C(C#N)C(=O)N1 +1298,Cyano_pyridone_G,"N1(c2ccc(O[CH2,CH3])cc2)C(=[OX1])C(C#[NX1])=CC(n3cncc3)=N1",*Oc1ccc(N2N=C(n3ccnc3)C=C(C#N)C2=O)cc1 +1299,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12 +1300,Thio_aldehyd_A,"[#1,#6][C!H0](=[SX1])",*C=S +1301,Thio_amide_A,"[#6!H0]1=,:[#6]-,:[#8]-,:[#6](=,:[#6!H0]1)C(=[SX1])N5[CH2][CH2]*[CH2][CH2]5",S=C(C1=CC=CO1)N1[CH2][CH2]*[CH2][CH2]1 +1302,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc +1303,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1 +1304,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C +1305,Thio_amide_E,"c1cccnc1C(=S)[N!H0]c2ccccc2O[CH2,CH3]",*Oc1ccccc1NC(=S)c1ccccn1 +1306,Thio_amide_F,acC(=S)[N!H0][N!H0]ca,*cNNC(=S)c* +1307,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1 +1308,Thio_ester_B,"ccC(=[SX1])[SX2][C!H0][CH2,CH3,$(cc)]",*CSC(=S)cc +1309,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1 +1310,Thio_ene_amine_A,"S=CC([CH2,CH3])=C([CH2,CH3])N([CH2,CH3])[CH2,CH3]",*C(C=S)=C(*)N(*)* +1311,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O +1312,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1 +1313,Thio_pyridine_A,c1(nanc(c2o[cH][cH][cH]2)n1)S[CX4],CSc1n*nc(c2[cH][cH][cH]o2)n1 +1314,Thio_thiomorph_Z,"[OX1]=C(N3CCSCC3)c9c([cH][cH][cH][cH]9)S[CH2,CH3]",*Sc1[cH][cH][cH][cH]c1C(=O)N1CCSCC1 +1315,Thio_urea_A,"c1c([N!H0][CX3](=[SX1])[N!H0][CH2][CH2][CH2]N([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1316,Thio_urea_B,"c1c([#7!H0]C(=S)[#7!H0][CH2][CH2][#7]([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1317,Thio_urea_C,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]C(=[OX1])c2a[a!c]cc2,O=C(NNC(=S)Nc1ccccc1)c1*:*cc1 +1318,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1 +1319,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1 +1320,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1 +1321,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1 +1322,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1 +1323,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1 +1324,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S +1325,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12 +1326,Thio_urea_L,[CX4][SX2]C(=N-aaaa)[N!H0]N=[#6],*:*:*:*N=C(NN=C)SC +1327,Thio_urea_M,"cc[#7]([CH2,CH3])[CH2][CH2][CH2][#7!H0]C(=S)[#7!H0]c1c([F,Cl,Br,I])[cH]c([CH2,CH3])[cH][cH]1",*c1[cH][cH]c(NC(=S)N[CH2][CH2][CH2]N(*)cc)c(*)[cH]1 +1328,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1 +1329,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1 +1330,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2 +1331,Thio_urea_Q,"[cH]1[cH][cH][cH]c2[cH][cH][cH]c(c12)C([CH2,CH3])=N[N!H0]C(=S)[N!H0]ccc",*C(=NNC(=S)Nccc)c1[cH][cH][cH]c2[cH][cH][cH][cH]c12 +1332,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1 +1333,Thio_carbam_A,"[CH2,CH3]SC(=S)[N!H0][CH2]-cc",*SC(=S)N[CH2]cc +1334,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1 +1335,Thio_carbonate_B,"[OX1]=[#6]1-,:[#16]c2cccc(O[CH2,CH3])c2-,:[#8]1",*Oc1cccc2c1OC(=O)S2 +1336,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N +1337,Thio_imine_ium,"[CX4][#7+,#7v4]([CX4][OH1])=CS[C!H0]",CSC=*(C)C[OH] +1338,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12 +1339,Thiophene_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=CC(=[OX1])c1c([SX2])sc([$(C#[NX1]),$(C=[OX1])])c1",*c1cc(C(=O)C=CN(*)*)c(S)s1 +1340,Thiophene_D,"s1[cH][cH]c(O[CH2,CH3])c1C(=[OX1])[N!H0][N!H0]",*Oc1[cH][cH]sc1C(=O)NN +1341,Thiophene_E,"c1(sc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])C(=[OX1])[NH]c2nccs2",*C(C(=O)[NH]c1nccs1)c1[cH][cH]c(*)s1 +1342,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C +1343,Thiophene_amino_B,"c2ccccc2[#7!H0]c1sc([$([#6]=[#8]),$(C#[#7]),$([#6]([#8!H0])=[#6])])c([#7])c1[$(C#[#7]),$([#6](n)n)]",*c1sc(Nc2ccccc2)c(*)c1N +1344,Thiophene_amino_C,"[C!H0][CH2]c1sc([N!H0]C(=[OX1])CCC=[OX1])c([$(C(=[OX1])O),$(C#[NX1])])c1[CH2,CH3]",*c1c([CH2]C)sc(NC(=O)CCC=O)c1* +1345,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N +1346,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1 +1347,Thiophene_amino_F,[NH2]c1sc([NH]C(=[OX1])c3ccccc3)c(C#[NX1])c1c2aaaaa2,N#Cc1c([NH]C(=O)c2ccccc2)sc([NH2])c1c1*:*:*:*:*1 +1348,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH] +1349,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc +1350,Keto_naphthol_A,"[#6]C(=[OX1])c1cccc2cccc([OH1,NH2])c12",*c1cccc2cccc(C(C)=O)c12 +1351,Keto_thiophene,"c1(sc2ccccc2c1([CH2,CH3]))C(=[OX1])[CH2][CH2,CH3]",*[CH2]C(=O)c1sc2ccccc2c1* +1352,Keto_phenone_A,c1cccc5c1C(c8c5nacc8)=[OX1],O=C1c2ccccc2c2n*ccc21 +1353,Keto_phenone_B,c1cccc5c1C(C8C5=N[!#1!#6]=CC8)=[OX1],O=C1C2CC=*N=C2c2ccccc21 +1354,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12 +1355,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1 +1356,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1 +1357,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O +1358,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH] +1359,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O +1360,Keto_keto_beta_F,"[CH2,CH3]C([OH1])=C(C(=[OX1])[CH2,CH3])[C!H0]C#C",*C(=O)C(CC#C)=C(*)[OH] +1361,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21 +1362,Thiaz_ene_C,"[#6]1([F,Cl,Br,I,$([#7v4R,#7v4R+](=,:[#6R])-,:[#6R])])=,:[#6](-!@C=N)-,:[#16]-,:[#6](=[OX1])-,:[#7]1",*C1=C(C=N)SC(=O)N1 +1363,Acyl_het_A,"[#7v4,#7+](=,:*-,:*=,:*)-,:*=O",*=**=**=O +1364,Anil_di_alk_G,"[CX4]N([CX4])c1[cH][cH]c([#6]2=,:[#7]-,:[#6]=,:[#6]-,:*2)[cH][cH]1",CN(C)c1[cH][cH]c(C2=NC=C*2)[cH][cH]1 +1365,Anil_di_alk_H,"[cH]1c([N!H0]S(=[OX1])(=[OX1])c2caccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NS(=O)(=O)c2c*ccc2)[cH]1 +1366,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1 +1367,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21 +1368,Anil_di_alk_O,"[cH]1c([N!H0]C(=S)[N!H0]c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=S)Nc2ccccc2)[cH]1 +1369,Anil_di_alk_P,"[CH2,CH3]N([CH2,CH3])c1cc2nc(S[CH2,CH3])sc2cc1",*Sc1nc2cc(N(*)*)ccc2s1 +1370,Anil_di_alk_ene_A,"[CH2,CH3]N([CH2,CH3])C1=[C!H0]c2ccccc2[SX2]c3ccccc13",*N(*)C1=Cc2ccccc2Sc2ccccc21 +1371,Anil_di_alk_dhp,"N1C=C(C=[OX1])C(-c3ccc(N([CH2,CH3])[CH2,CH3])cc3)C2=C1(~[#7]~[#6](~[#16])~[#7]~[#6]2~[#7])",*N(*)c1ccc(C2C(C=O)=CNC3=C2C(~N)~N~C(~S)~N~3)cc1 +1372,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21 +1373,Anil_di_alk_coum,"c2ccccc2N([C!H0])[C!H0][C!H0][C!H0][N!H0]C(=[OX1])[#6]1-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6](=[OX1])-,:[#8]-,:[#6]([CH2,CH3])=,:1",*C1=CC(=O)OC(*)=C1C(=O)NCCCN(C)c1ccccc1 +1374,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1 +1375,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O +1376,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O +1377,Ene_one_amide_A,"c1ccccc1[C!H0]NC(=[OX1])C([N!H0][CH2,CH3])=[C!H0]C(=[OX1])c2ccc(O[CH2,CH3])cc2",*NC(=CC(=O)c1ccc(O*)cc1)C(=O)NCc1ccccc1 +1378,Ene_one_amide_B,"c13ccc2ccccc2c1[C!H0][CX4]NC3=[C!H0]C(=[OX1])N([CH2,CH3])[CH2,CH3]",*N(*)C(=O)C=C1NCCc2c1ccc1ccccc21 +1379,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1 +1380,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O +1381,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C +1382,Imine_one_B,"[N!H0](c1ccccc1)N=C(C(=[OX1])[CH2,CH3])[N!H0][$([N!H0]),$(cc)]",*NC(=NNc1ccccc1)C(*)=O +1383,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1 +1384,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1 +1385,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21 +1386,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C +1387,Imine_imine_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=NC([CH2,CH3])=NN([CH2,CH3])cc",*C(N=CN(*)*)=NN(*)cc +1388,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O +1389,Imine_one_fives_C,cc[N!R]=C2C(=[!#1!#6])c5ccccc5N2,*=C1C(=Ncc)Nc2ccccc21 +1390,Imine_one_fives_D,C1(=[!#1!#6])C(N=CS1)=O,*=C1SC=NC1=O +1391,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH] +1392,Imine_naphthol_A,"c12c([cH][cH][cH][cH]1)c(c([cH][cH]2)C(=N-cc)[CH2,CH3])[OH1]",*C(=Ncc)c1[cH][cH]c2[cH][cH][cH][cH]c2c1[OH] +1393,Pyrrole_C,"[#7]1([CX4])-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6!H0]=,:[#6]1cc",*C1=CC=C(cc)N1C +1394,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S +1395,Pyrrole_E,"[#7]1(c2[cH]a[a!c]a2)-,:[#6]([CX4])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CX4]",CC1=CC=C(C)N1c1*:*:*[cH]1 +1396,Pyrrole_F,[cH]1[cH]n(-c2[a!c]ccc2C#[NX1])c[cH]1,N#Cc1cc*c1-n1c[cH][cH][cH]1 +1397,Pyrrole_G,"n1(c2c[cH]c([$([NH2]),$(cn)])c[cH]2)[cH][cH][cH][cH]1",*c1c[cH]c(n2[cH][cH][cH][cH]2)c[cH]1 +1398,Pyrrole_H,"C1=[Nv4,N+]([#6])CC[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]12",C*1=CC2=CC=CN2CC1 +1399,Pyrrole_I,"[#7]1([CH2,CH3])-,:[#6]2=,:[#6](-,:[#6]:[#6]-,:[#6]2=[OX1])-,:[#6]=,:[#6]1[CH2,CH3]",*C1=CC2=C(C(=O)C:C2)N1* +1400,Pyrrole_J,"[#6]1(=,:[#6]2-,:[#6](=,:[#6](-,:[#7]1C(O)=[OX1])[CH2,CH3])S[CH2]S2)[CH2,CH3]",*C1=C2S[CH2]SC2=C(*)N1C(O)=O +1401,Pyrrole_K,"[#6]1(-,:[#7!H0]-,:[#6](c2[cH][cH][cH][cH][cH]2)=,:[#6]([CH2,CH3])-,:[#6H]=,:1)C(=[OX1])[OH1]",*C1=C(c2[cH][cH][cH][cH][cH]2)NC(C(=O)[OH])=[CH]1 +1402,Pyrrole_L,"[n!H0]1c(C(=[OX1])O[CH2,CH3])c([CH2,CH3])c([CH2][CH2,CH3])c1[CH2][CH2,CH3]",*[CH2]c1nc(C(=O)O*)c(*)c1[CH2]* +1403,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1 +1404,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1 +1405,Pyrrole_O,"[#7]1([CH2,CH3])-,:[#6]([CH2,CH3])=,:[#6](C(=[OX1])[#6])-,:[#6]=,:[#6]1-cc",*C1=C(C(C)=O)C=C(cc)N1* +1406,Thiaz_ene_D,"c2ccccc2[#7][#6]1=,:[#7+,#7v4]-,:[#6](c3ccccc3)=,:[#6][#16]1",*1=C(Nc2ccccc2)SC=C1c1ccccc1 +1407,Thiaz_ene_E,"C1(S[#6R])=C([C!H0]([#6])[#6])SC(N1([H,CH2,CH3]))=[OX1]",*N1C(=O)SC(C(C)C)=C1SC +1408,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21 +1409,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O +1410,Quinone_D,"[!#1!#6]=[#6]1[#6]=,:[#6][#6]=,:[#6][#6]1=[!#1!#6]",*=C1C=CC=CC1=* +1411,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1 +1412,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1 +1413,Diazox_C,N2=Nc1n[a!c]nc1N=Ncc2,*1nc2c(n1)N=NccN=N2 +1414,Diazox_D,[C!H0]1([OH1])c2n[a!c]nc2[C!H0]([OH1])C=C1,[OH]C1C=CC([OH])c2n*nc21 +1415,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2] +1416,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1 +1417,Sulfonamide_C,[cH]1c([N!H0]S(=[OX1])(=[OX1])c2ccc([!#1!#6])cc2)[cH]c3c(O[CH2]O3)[cH]1,*c1ccc(S(=O)(=O)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)cc1 +1418,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1 +1419,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc +1420,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1 +1421,Sulfonamide_G,"[CH3]c5nc([N!H0]S(c2[cH][cH]c([cH][cH]2)O[CH2][CH2][CH2,CH3])(=[OX1])(=[OX1]))[cH][cH][cH]5",*[CH2][CH2]Oc1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]c([CH3])n2)[cH][cH]1 +1422,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1 +1423,Sulfonamide_I,"S(=[OX1])(=[OX1])(c1cn([CH2,CH3])cn1)[N!H0]c2cnn([CH2]ccO[CH2,CH3])c2",*Occ[CH2]n1cc(NS(=O)(=O)c2cn(*)cn2)cn1 +1424,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1 +1425,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc +1426,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1 +1427,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1 +1428,Thiazole_amine_B,"c1(ccc([CH2,CH3])cc1)-c2nc([NH2])sc2[CH3]",*c1ccc(-c2nc([NH2])sc2[CH3])cc1 +1429,Thiazole_amine_C,"c1([N!H0][CH2]c2[cH][cH][cH]o2)nc(aaa([$(O[CH2,CH3]),CH2,CH3])aa)[cH]s1",**(:*:*):*:*c1[cH]sc(N[CH2]c2[cH][cH][cH]o2)n1 +1430,Thiazole_amine_D,"[#16]1-,:[#6]([N!H0]c2c([CH2,CH3,$(cc)])cccc2)=,:[#7+,#7v4]([CH2,CH3])-,:[#6]([#6])=,:[#6H]1",**1=C(Nc2ccccc2*)S[CH]=C1C +1431,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O +1432,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1 +1433,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1 +1434,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1 +1435,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1 +1436,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3 +1437,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1 +1438,Thiazole_amine_M,"c1([N!H0]cc[CH2,CH3])nc(c2ccncc2)[cH]s1",*ccNc1nc(c2ccncc2)[cH]s1 +1439,Thiazole_amine_N,"[CH2,CH3]Oc1[cH][cH]c(O[CH2,CH3])[cH]c1[N!H0]c2scc(-c3ccc(O[CH2,CH3])cc3)n2",*Oc1ccc(-c2csc(Nc3[cH]c(O*)[cH][cH]c3O*)n2)cc1 +1440,Furan_acid_A,"c1(oc([CH2,CH3])c([CH2]Occ)[cH]1)[CX3](=[OX1])[OH1]",*c1oc(C(=O)[OH])[cH]c1[CH2]Occ +1441,Furan_A,"c1(oc([CH2,CH3])[cH][cH]1)[C!H0]([OH1])C#C[CX4]",*c1[cH][cH]c(C([OH])C#CC)o1 +1442,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N +1443,Colchicine_B,"[CH2,CH3]Sc1ccc(cc1)C2=CC(=[OX1])[#6]3=,:[#6]-,:[#8]-,:[#6]=,:[#6]3C([OH1])=C2",*Sc1ccc(C2=CC(=O)C3=COC=C3C([OH])=C2)cc1 +1444,Colchicine_het,"c1cccc3-,:[#7]([CH2,CH3])-,:[#6](=NN=[#6]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]2)-,:[#16]-,:c13",*N1C(=NN=C2C=CC=CC=C2)Sc2ccccc21 +1445,Rhod_sat_B,"N1(c2c([CH2,CH3])cccc2)C(=S)N([CH2]aaaaa)[CH2]C1=[OX1]",*c1ccccc1N1C(=O)[CH2]N([CH2]*:*:*:*:*)C1=S +1446,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1 +1447,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O +1448,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1 +1449,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1 +1450,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1 +1451,Melamine_A,"o1[cH][cH][cH]c1[CH2][N!H0]c1c2ccccc2nc([N!H0]c4c([H,CH2,CH3,SX2,$(O[C!H0])])cc([H,CH2,CH3,SX2,$(O[C!H0])])c([H,CH2,CH3,SX2,$(O[C!H0])])c4)n1",*c1cc(*)c(Nc2nc(N[CH2]c3[cH][cH][cH]o3)c3ccccc3n2)cc1* +1452,Melamine_B,"n1c(N([CH2,CH3])[CH2,CH3])nc(N([CH2,CH3])[CH2,CH3])nc1N([C!H0])C=[OX1]",*N(*)c1nc(N(*)*)nc(N(C)C=O)n1 +1453,Imidazole_B,"[CH2,CH3][CH2]S[CH2][#6]1=,:[#6]-,:[#7!H0]-,:[#6]=,:[#7]1",*[CH2]S[CH2]C1=CNC=N1 +1454,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2 +1455,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1 +1456,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1 +1457,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23 +1458,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2 +1459,Naphth_ene_one_A,"c1cc3c4c(c1)cccc4C(=CC3=[OX1])O[CH2,CH3]",*OC1=CC(=O)c2cccc3cccc1c23 +1460,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F +1461,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2 +1462,Coumarin_A,"c1(O[C!H0])[cH][cH]c2c3[cH][cH]c(O[CH2,CH3])[cH]c3-,:[#6](=[OX1])-,:[#8]c2c1",*Oc1[cH][cH]c2c([cH]1)C(=O)Oc1cc(OC)[cH][cH]c12 +1463,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O +1464,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1 +1465,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1 +1466,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1 +1467,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O +1468,Coumarin_G,"c1c([F,Cl,Br,I])cc2c(c1[F,Cl,Br,I])OC(=[N!H0])C(C(=[OX1])[NH2])=[C!H0]2",*c1cc(*)c2c(c1)C=C(C([NH2])=O)C(=N)O2 +1469,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1 +1470,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O +1471,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O +1472,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1 +1473,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH] +1474,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH] +1475,Tetrazole_A,"[CH2,CH3][#6]1=,:[#7]-,:[#7]=,:[#7]-,:[#7]1c2[cH][cH]c(O[CH3])[cH][cH]2",*C1=NN=NN1c1[cH][cH]c(O[CH3])[cH][cH]1 +1476,Misc_aminal_acid,"c1ccc4c(c1)COC(N4C(=[OX1])[CH2,CH3])(C(=[OX1])[OH1])[CH2,CH3]",*C(=O)N1c2ccccc2COC1(*)C(=O)[OH] +1477,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1 +1478,Misc_anilide_A,"c1([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH][cH]c([CH2,CH3])c([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH]1",*c1[cH][cH]c(NC(=O)[CH2][CH2]cc)[cH]c1NC(=O)[CH2][CH2]cc +1479,Misc_anilide_B,"c1([N!H0]C(=[OX1])[N!H0][CH2][CH2][CH2,CH3])c([CH2,CH3])[cH]c(Br)[cH]c1[CH2,CH3]",*[CH2][CH2]NC(=O)Nc1c(*)[cH]c(Br)[cH]c1* +1480,Misc_anisole_A,"c1(c([cH]c5c([cH]1)c([cH]c([cH]5)c3[cH][cH]c(c([cH]3)O[CH2,CH3])O[CH2,CH3])[N!H0][CH3])O[CH2,CH3])O[CH2,CH3]",*Oc1[cH][cH]c(c2[cH]c(N[CH3])c3[cH]c(O*)c(O*)[cH]c3[cH]2)[cH]c1O* +1481,Misc_anisole_B,"c1([cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH][cH]1)C(=[OX1])[CH2]N([CH2,CH3])c2ccc([CH2,CH3])cc2",*Oc1[cH][cH]c(C(=O)[CH2]N(*)c2ccc(*)cc2)[cH]c1O* +1482,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3] +1483,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1 +1484,Misc_furan_A,"c3c([CH2,CH3])c([CH2,CH3])oc3[CH2]N[CH2][C!H0](O[CH2,CH3])[CH2]Oc1ccc2c(O[CH2]O2)c1",*OC([CH2]N[CH2]c1cc(*)c(*)o1)[CH2]Oc1ccc2c(c1)O[CH2]O2 +1485,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1 +1486,Misc_phthal_thio_N,"c1(c2ccccc2)nc(N([CH2,CH3])[CH2][CH2]NC(=[OX1])c3c(C(=[OX1])[OH1])cccc3)sn1",*N([CH2][CH2]NC(=O)c1ccccc1C(=O)[OH])c1nc(c2ccccc2)ns1 +1487,Misc_pyridine_OC,"[OX1]=C(c1[cH]c(O[CH3])nc(O[CH3])[cH]1)[N!H0][C!H0]([CH2,CH3])[CH2,CH3]",*C(*)NC(=O)c1[cH]c(O[CH3])nc(O[CH3])[cH]1 +1488,Misc_pyrrole_benz,"[#7]1(-c2[cH][cH][cH][cH]c2C(=[OX1])[N!H0][C!H0]([CH2,CH3])[CH2]O-cc)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",*C([CH2]Occ)NC(=O)c1[cH][cH][cH][cH]c1N1C=CC=C1 +1489,Misc_pyrrole_thiaz,"c1([C!H0]([CH2,CH3])[CH2][CH2]N[CH2]c2[n!H0]ccc2)nc(-c3ccccc3)[c!H0]s1",*C([CH2][CH2]N[CH2]c1cccn1)c1nc(-c2ccccc2)cs1 +1490,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH] +1491,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH] +1492,Misc_urea_A,"c1(C([CX4])([CX4])[N!H0]C(=[OX1])N([CH2][CH2,CH3])[CH2][CH2][CH2][CH2]-cc)[cH][cH][cH]c(C(=[CH2])[CH2,CH3])[cH]1",*[CH2]N([CH2][CH2][CH2][CH2]cc)C(=O)NC(C)(C)c1[cH][cH][cH]c(C(*)=C)[cH]1 +1493,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1 +1494,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1 +1495,Pyrazole_amino_A,"[#6]1=,:[#6]([NH2])-,:[#7]-,:[#7]=,:[#6]1-[#6]2=,:[#6]([CH2,CH3])-,:[#8]-,:[#6!H0]=,:[#6!H0]2",*C1=C(C2=NNC([NH2])=C2)C=CO1 +1496,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1 +1497,Indole_3yl_alk_B,"c12[cH][cH][cH][cH]c1-,:[#6]([CH2,CH3])=,:[#6](-cc)-,:[#7]2-!@cc",*C1=C(cc)N(cc)c2[cH][cH][cH][cH]c21 +1498,Mannich_B,"c1c[cH]c2O[CH2]N(ccO[CH2,CH3])[CH2]c2[cH]1",*OccN1[CH2]Oc2[cH]cc[cH]c2[CH2]1 +1499,Mannich_catechol_A,"[cH]1c([#8])c([#8])[cH]c2c1O[CH2]N([CH2,CH3])[CH2]2",*N1[CH2]Oc2[cH]c(O)c(O)[cH]c2[CH2]1 +1500,Dyes7A,"c1ccccc1N([CH2,CH3])[C!H0]=[C!H0]C=!@[C!H0][C!H0]=CC=&@Nc2ccccc2",*N(C=CC=CC=CC=Nc1ccccc1)c1ccccc1 +1501,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1 +1502,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1 +1503,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH] +1504,Retinoic acid derivatives_1,"[$([OH1][CX3](=[OX1])c1[cH][cH]c(-c2c[cH]c3[cH]c([H,CX4])c([H,CX4])[cH]c3[cH]2)[cH][cH]1),$([OH1][CX3](=[OX1])c1[cH]c2[cH]cc(-c3[cH]c([H,CX4])c([H,CX4])[cH][cH]3)[cH]c2[cH][cH]1)]",* +1505,Thiazole_amine_I,"[CH2,CH3][N!H0]C=N[N!H0][#6]1=,:[#7]-,:[#6](-cc)=,:[#6!H0]-,:[#16]1",*NC=NNC1=NC(cc)=CS1 +1506,Indol_3yl_alk,"[H,CH2,CH3][#7]1-,:[#6]([CH2,CH3,$([a!c](:[#6]-,:[#7])),$([C!H0][#7]),$([C!H0]([CH2,CH3])[N!H0][CH2,CH3]),$([C!H0]([CH2,CH3])[CH2][N!H0][CH2,CH3])])=,:[#6]([CX4!H0])-,:c2[cH]cccc12",*C1=C(C)c2[cH]cccc2N1* +1507,Tetrazole_hzide,"a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])[N!H0][N!H0][#6]2=,:[#7]-,:[#7]=,:[#7]-,:[#7]2[#6]",CN1N=NN=C1NNC(=O)C=C*1:*:*:*:*:*:1 +1508,Three-membered heterocycles (LS),[!#6!#1]1~*~*~1,*1~*~*~1 +1509,Three-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~1,*1~C~C~1 +1510,Saturated three-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-1,*1CC1 +1511,Unsaturated three-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1~[#6]=[#6]~1),$([!#1!#6]1=[#6]~[#6]~1)]",* +1512,Three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[#6]~1,*1~*~C~1 +1513,Saturated three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[#6]-1,*1*C1 +1514,Unsaturated three-membered heterocycles with two heteroatoms (LS),"[$([!#1!#6]1=[!#1!#6]~[#6]~1),$([!#1!#6]1~[!#6!#1]=[#6]~1)]",* +1515,Three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~1,*1~*~*~1 +1516,Saturated three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-1,*1**1 +1517,Unsaturated three-membered heterocycles with three heteroatoms (LS),[!#1!#6]1~[!#1!#6]=[!#1!#6]~1,*1~*=*~1 +1518,Three-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~1,*1~*~*~1 +1519,Three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6&R1]~[#6&R1]~1,*1~C~C~1 +1520,Saturated three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6&R1]-[#6&R1]-1,*1CC1 +1521,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1 +1522,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1 +1523,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1 +1524,Unsaturated three-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1~[#6R1]=[#6R1]~1),$([!#1!#6;R1]1=[#6R1]~[#6R1]~1)]",* +1525,Azirines (HS),"[$([#7R1]1-[#6R1]=[#6R1]-1),$([#7R1]1=[#6R1]-[#6R1]-1)]",* +1526,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1 +1527,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1 +1528,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1 +1529,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1 +1530,Three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~1,*1~*~C~1 +1531,Saturated three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-1,*1*C1 +1532,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1 +1533,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1 +1534,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1 +1535,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1 +1536,Unsaturated three-membered heterocycles with two heteroatoms (HS),"[$([!#1!#6;R1]1=[!#1!#6;R1]~[#6R1]~1),$([!#1!#6;R1]1~[!#6!#1;R1]=[#6R1]~1)]",* +1537,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1 +1538,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1 +1539,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1 +1540,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1 +1541,Three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~1 +1542,Saturated three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**1 +1543,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1 +1544,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1 +1545,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1 +1546,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1 +1547,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1 +1548,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1 +1549,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1 +1550,Unsaturated three-membered heterocycles with three heteroatoms (HS),[!#1!#6;R1]1-[!#6!#1;R1]=[!#6!#1;R1]1,*1*=*1 +1551,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1 +1552,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1 +1553,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1 +1554,Four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~1)]",* +1555,Saturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1-[!#6!#1]-[#6]-[#6]-1),$([!#6!#1]1-[#6]-[!#6!#1]-[#6]-1)]",* +1556,Unsaturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]=[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]=[#6]~1),$([!#6!#1]1=[#6]~[!#6!#1]~[#6]~1)]",* +1557,Four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~C~*~1 +1558,Saturated four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[#6]-1,*1*C*1 +1559,Unsaturated four-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]=[#6]~1)]",* +1560,Four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~1 +1561,Saturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1***1 +1562,Unsaturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*=*~1 +1563,Four-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~1 +1564,Four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~1 +1565,Saturated four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6R1]-[#6R1]-[#6R1]-1,*1CCC1 +1566,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1 +1567,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1 +1568,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1 +1569,Unsaturated four-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]=[#6R1]~[#6R1]~1)]",* +1570,Azetines (HS),"[$([#7R1]1=[#6R1]-[#6R1]-[#6R1]-1),$([#7R1]1-[#6R1]=[#6R1]-[#6R1]-1)]",* +1571,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1 +1572,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1 +1573,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1 +1574,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1 +1575,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1 +1576,Four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1577,Saturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-[#6R1]-1),$([!#6!#1;R1]1-[#6R1]-[!#6!#1;R1]-[#6R1]-1)]",* +1578,Diazetidines (HS),"[$([NR1]1[CR1][CR1][NR1]1),$([NR1]1[CR1][NR1][CR1]1)]",* +1579,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1 +1580,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1 +1581,Dioxetanes (HS),"[$([OR1]1[OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]1)]",* +1582,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1 +1583,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1 +1584,Dithietanes (HS),"[$([SX2R1]1[SX2R1][CR1][CR1]1),$([SX2R1]1[CR1][SX2R1][CR1]1)]",* +1585,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1 +1586,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1 +1587,Unsaturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]=[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]=[#6R1]~1),$([!#6!#1;R1]1=[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1588,Diazetines (HS),"[$([#7]1=,:[#7]-,:[#6]-,=,:[#6]-,:1),$([#7]1-,:[#7]=,:[#6]-,:[#6]-,=,:1),$([#7]1-,:[#7]-,:[#6]=,:[#6]-,=,:1),$([#7]1=,:[#6]-,:[#7]-,=,:[#6]-,:1)]",* +1589,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1 +1590,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1 +1591,Four-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~1,*1~C~C~C~1 +1592,Saturated four-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-[#6]-1,*1CCC1 +1593,Unsaturated four-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]=[#6]~[#6]~1)]",* +1594,Diazirenes (HS),"[$([#7R1]1-[#7R1]=[#6R1]-1),$([#7R1]1=[#7R1]-[#6R1]-1)]",* +1595,Four-membered heterocycles (LS),[!#6!#1]1~*~*~*~1,*1~*~*~*~1 +1596,Five-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~1,*1~*~*~*~*~1 +1597,Five-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~1 +1598,Saturated five-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCC1,*1CCCC1 +1599,Unsaturated five-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=CCCC1),$([!#6!#1]1C=CCC1),$([!#6!#1]1CC=CC1),$([!#6!#1]1=CC=CC1);!$(n1cccc1)]",* +1600,Aromatic five-membered heterocycles with one heteroatom (LS),[a!#6]1cccc1,*1cccc1 +1601,Five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1602,Saturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCC1),$([!#6!#1]1C[!#6!#1]CC1)]",* +1603,Unsaturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]C-,=CC1),$([!#6!#1]1[!#6!#1]=CCC1),$([!#6!#1]1[!#6!#1]C=CC1),$([!#6!#1]1=C[!#6!#1]-,=CC1),$([!#6!#1]1C[!#6!#1]CC=1),$([!#6!#1]1C[!#6!#1]C=C1)]",* +1604,Aromatic five-membered heterocycles with two heteroatoms (LS),"[$([a!#6]1[a!#6]ccc1),$([a!#6]1c[a!#6]cc1)]",* +1605,Five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1606,Saturated five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]C1)]",* +1607,Aromatic five-membered heterocycles with three heteroatoms (LS),"[$([a!#6]1[a!#6][a!#6]cc1),$([a!#6]1[a!#6]c[a!#6]c1)]",* +1608,Five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~1 +1609,Saturated five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]C1,*1**C*1 +1610,Unsaturated five-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1][!#6!#1]-,=[!#6!#1][#6]1),$([!#6!#1]1[!#6!#1]=[!#6!#1][!#6!#1][#6]1),$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1][#6]=1)]",* +1611,Aromatic five-membered heterocycles with four heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6]c1,*1:*:*c*:1 +1612,Five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~1 +1613,Saturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1****1 +1614,Unsaturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1=[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1**=**1 +1615,Aromatic five-membered heterocycles with five heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6][a!#6]1,*1:*:*:*:*:1 +1616,Five-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~1 +1617,Five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~1 +1618,Saturated five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1]1,*1CCCC1 +1619,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1 +1620,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1 +1621,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1 +1622,Unsaturated five-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1]=[CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1]=[CR1][CR1]1),$([!#6!#1;R1]1=[CR1][CR1]=[CR1][CR1]1);!$(n1cccc1)]",* +1623,Pyrrolines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1624,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1 +1625,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1 +1626,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1 +1627,Dihydrofurans (HS),"[$([OR1]1[CR1]=[CR1][CR1][CR1]1),$([OR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1628,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1 +1629,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1 +1630,Dihydrothiophenes (HS),"[$([SR1]1[CR1]=[CR1][CR1][CR1]1),$([SR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1631,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1 +1632,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1 +1633,Aromatic five-membered heterocycles with one heteroatom (HS),[a!#6;R1]1[cR1][cR1][cR1][cR1]1,*1cccc1 +1634,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1 +1635,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1 +1636,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1 +1637,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1 +1638,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1 +1639,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1 +1640,Five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1)]",* +1641,Saturated five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1]1)]",* +1642,Diazolidines (HS),"[$([NR1]1[NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1]1)]",* +1643,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1 +1644,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1 +1645,Dioxolanes (HS),"[$([OR1]1[OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1]1)]",* +1646,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1 +1647,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1 +1648,Dithiolanes (HS),"[$([SR1]1[SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1]1)]",* +1649,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1 +1650,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1 +1651,Pyrazolines (HS),"[$([NR1]1=[NR1][CR1][CR1][CR1]1),$([NR1]1[NR1]=[CR1][CR1][CR1]1),$([NR1]1[NR1][CR1]=[CR1][CR1]1)]",* +1652,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1 +1653,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1 +1654,Imidazolines (HS),"[$([NR1]1=[CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1]=[CR1][CR1]1),$([NR1]1[CR1][NR1][CR1]=[CR1]1)]",* +1655,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1 +1656,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1 +1657,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1 +1658,Dioxolenes (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]=[CR1]1)]",* +1659,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1 +1660,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1 +1661,Dithiolenes (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]1),$([SR1]1[CR1][SR1][CR1]=[CR1]1)]",* +1662,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1 +1663,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1 +1664,Aromatic five-membered heterocycles with two heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][cR1][cR1][cR1]1),$([a!#6;R1]1[cR1][a!#6;R1][cR1][cR1]1)]",* +1665,Diazoles (HS),"[$([nR1]1[nR1][cR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][cR1]1)]",* +1666,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1 +1667,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1 +1668,Oxazoles (HS),"[$([oR1]1[nR1][cR1][cR1][cR1]1),$([oR1]1[cR1][nR1][cR1][cR1]1)]",* +1669,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1 +1670,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1 +1671,Thiazoles (HS),"[$([sR1]1[nR1][cR1][cR1][cR1]1),$([sR1]1[cR1][nR1][cR1][cR1]1)]",* +1672,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1 +1673,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1 +1674,Five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1675,Saturated five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1676,Triazolidines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1]1)]",* +1677,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1 +1678,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1 +1679,Trioxolanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1]1)]",* +1680,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1 +1681,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1 +1682,Trithiolanes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1]1)]",* +1683,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1 +1684,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1 +1685,"1,2,3-Triazolines (HS)","[$([NR1]1=[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][NR1][CR1][CR1]=1),$([NR1]1[NR1][NR1][CR1]=[CR1]1)]",* +1686,"1,2,4-Triazolines (HS)","[$([NR1]1=[NR1][CR1][NR1][CR1]1),$([NR1]1[NR1]=[CR1][NR1][CR1]1),$([NR1]1[NR1][CR1]=[NR1][CR1]1)]",* +1687,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1 +1688,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1 +1689,Aromatic five-membered heterocycles with three heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][a!#6;R1][cR1][cR1]1),$([a!#6;R1]1[a!#6;R1][cR1][a!#6;R1][cR1]1)]",* +1690,Triazoles (HS),"[$([nR1]1[nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1]1)]",* +1691,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1 +1692,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1 +1693,Oxadiazoles (HS),"[$([oR1]1[nR1][nR1][cR1][cR1]1),$([oR1]1[nR1][cR1][nR1][cR1]1),$([oR1]1[nR1][cR1][cR1][nR1]1),$([oR1]1[cR1][nR1][nR1][cR1]1)]",* +1694,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1 +1695,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1 +1696,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1 +1697,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1 +1698,Five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~1 +1699,Saturated five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1][CR1]1,*1**C*1 +1700,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1 +1701,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1 +1702,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1 +1703,Unsaturated five-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1][!#6!#1;R1]-,=[!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1]=[!#6!#1;R1][!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][#6R1]=1)]",* +1704,Aromatic five-membered heterocycles with four heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][cR1]1,*1:*:*c*:1 +1705,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1 +1706,Oxatriazoles (HS),"[$([oR1]1[nR1][nR1][nR1][cR1]1),$([oR1]1[nR1][nR1][cR1][nR1]1)]",* +1707,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1 +1708,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1 +1709,Thiatriazoles (HS),"[$([sR1]1[nR1][nR1][nR1][cR1]1),$([sR1]1[nR1][nR1][cR1][nR1]1)]",* +1710,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1 +1711,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1 +1712,Five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~1 +1713,Saturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1****1 +1714,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1 +1715,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1 +1716,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1 +1717,Unsaturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1=[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**=**1 +1718,Aromatic five-membered heterocycles with five heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][a!#6;R1]1,*1:*:*:*:*:1 +1719,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1 +1720,Six-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~*~1,*1~*~*~*~*~*~1 +1721,Six-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~C~1 +1722,Saturated six-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCCC1,*1CCCCC1 +1723,Unsaturated six-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1=C~C~C~C~C~1),$([!#1!#6]1~C=C~C~C~C~1),$([!#1!#6]1~C~C=C~C~C~1);!$([a!c]1ccccc1)]",* +1724,Aromatic six-membered heterocycles with one heteroatom (LS),[a!c]1ccccc1,*1ccccc1 +1725,Six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1726,Saturated six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCCC1),$([!#6!#1]1C[!#6!#1]CCC1),$([!#6!#1]1CC[!#6!#1]CC1)]",* +1727,Aromatic six-membered heterocycles with two heteroatoms (LS),"[$([a!c]1[a!c]cccc1),$([a!c]1c[a!c]ccc1),$([a!c]1cc[a!c]cc1)]",* +1728,Six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1729,Saturated six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CCC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]CC1),$([!#6!#1]1C[!#6!#1]C[!#6!#1]C1)]",* +1730,Aromatic six-membered heterocycles with three heteroatoms (LS),"[$([a!c]1[a!c][a!c]ccc1),$([a!c]1[a!c]c[a!c]cc1),$([a!c]1c[a!c]c[a!c]c1)]",* +1731,Six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[!#6!#1]~[#6]~1)]",* +1732,Saturated six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1][!#6!#1]C[!#6!#1]C1),$([!#6!#1]1[!#6!#1]C[!#6!#1][!#6!#1]C1)]",* +1733,Aromatic six-membered heterocycles with four heteroatoms (LS),"[$([a!c]1[a!c][a!c][a!c]cc1),$([a!c]1[a!c][a!c]c[a!c]c1),$([a!c]1[a!c]c[a!c][a!c]c1)]",* +1734,Six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~*~1 +1735,Saturated six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-C-1,*1**C**1 +1736,Aromatic six-membered heterocycles with five heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c]c1,*1:*:*c*:*:1 +1737,Saturated six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1*****1 +1738,Unsaturated six-membered heterocycles with six heteroatoms (LS),[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1739,Aromatic six-membered heterocycles with six heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c][a!c]1,*1:*:*:*:*:*:1 +1740,Six-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~*~1 +1741,Six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~C~1 +1742,Saturated six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1][CR1]1,*1CCCCC1 +1743,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1 +1744,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1 +1745,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1 +1746,Unsaturated six-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1=[CR1]~[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]=[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]~[CR1]=[CR1]~[CR1]~[CR1]~1);!$([a!c]1ccccc1)]",* +1747,Tetrahydropyridines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1][CR1]1)]",* +1748,Dihydropyridines (HS),"[$([NR1]1=[CR1][CR1]-,=[CR1]-,=[CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]-,=[CR1]-,=1),$([NR1]1[CR1]=[CR1][CR1]=[CR1][CR1]1)]",* +1749,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1 +1750,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1 +1751,Aromatic six-membered heterocycles with one heteroatom (HS),[a!c;R1]1[cR1][cR1][cR1][cR1][cR1]1,*1ccccc1 +1752,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1 +1753,Six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~1)]",* +1754,Saturated six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1][!#6!#1;R1][CR1][CR1]1)]",* +1755,Hexahydrodiazines,"[$([NR1]1[NR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1][NR1][CR1][CR1]1)]",* +1756,Dioxanes,"[$([OR1]1[OR1][CR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][CR1][OR1][CR1][CR1]1)]",* +1757,Dithianes,"[$([SR1]1[SR1][CR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][CR1][SR1][CR1][CR1]1)]",* +1758,Dioxines (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]=[CR1]1),$([OR1]1[CR1]=[CR1][OR1][CR1]=[CR1]1)]",* +1759,Aromatic six-membered heterocycles with two heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][cR1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][cR1][a!c;R1][cR1][cR1]1)]",* +1760,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1 +1761,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1 +1762,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1 +1763,Six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1764,Saturated six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1765,Hexahydrotriazines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][NR1][CR1]1)]",* +1766,Trioxanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][OR1][CR1]1)]",* +1767,Trithianes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][SR1][CR1]1)]",* +1768,Aromatic six-membered heterocycles with three heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][a!c;R1][cR1]1)]",* +1769,Triazines (HS),"[$([nR1]1[nR1][nR1][cR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][nR1][cR1]1)]",* +1770,Saturated six-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][!#6!#1;R1][CR1]1)]",* +1771,Hexahydrotetrazines (HS),"[$([NR1]1[NR1][NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][NR1][CR1]1),$([NR1]1[NR1][NR1][CR1][NR1][CR1]1)]",* +1772,Tetroxanes (HS),"[$([OR1]1[OR1][OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][OR1][CR1]1)]",* +1773,Tetrathianes (HS),"[$([SR1]1[SR1][SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][SR1][CR1]1)]",* +1774,Aromatic six-membered heterocycles with four heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][a!c;R1][cR1][a!c;R1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][a!c;R1][cR1]1)]",* +1775,Tetrazines (HS),"[$([nR1]1[nR1][nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][nR1][cR1][nR1][cR1]1),$([nR1]1[nR1][cR1][nR1][nR1][cR1]1)]",* +1776,Six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~*~1 +1777,Saturated six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[CR1]-1,*1**C**1 +1778,Aromatic six-membered heterocycles with five heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][cR1]1,*1:*:*c*:*:1 +1779,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1 +1780,Six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~*~1 +1781,Saturated six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1*****1 +1782,Unsaturated six-membered heterocycles with six heteroatoms (HS),[$([!#6!#1;R1]1=[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1783,Aromatic six-membered heterocycles with six heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][a!c;R1]1,*1:*:*:*:*:*:1 +1784,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1 +1785,Six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~*~1 +1786,Dithiines (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]=[CR1]1),$([SR1]1[CR1]=[CR1][SR1][CR1]=[CR1]1)]",* +1787,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1 +1788,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1 +1789,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1 +1790,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C +1791,Allyl halides,"[CX3]=[CX3][CX4][F,Cl,Br,I]",*CC=C +1792,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF +1793,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl +1794,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr +1795,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI +1796,Vinyl fluorides,F[CX3]=[CX3],C=CF +1797,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl +1798,Vinyl bromides,Br[CX3]=[CX3],C=CBr +1799,Vinyl iodides,I[CX3]=[CX3],C=CI +1800,Alkynyl fluorides,F[CX2]#[CX2],C#CF +1801,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl +1802,Alkynyl iodides,I[CX2]#[CX2],C#CI +1803,Alkynyl bromides,Br[CX2]#[CX2],C#CBr +1804,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC +1805,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc +1806,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc +1807,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH] +1808,"1,3 – Diphenols",c([OH1])[aR1]c([OH1]),[OH]c*c[OH] +1809,"1,4 - Diphenols",c1([OH1])aac([OH1])aa1,[OH]c1*:*c([OH])*:*1 +1810,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH] +1811,"1,3 – Dithiophenols",c([SH1])[aR1]c([SH1]),[SH]c*c[SH] +1812,"1,4 – Dithiophenols",c1([SH1])aac([SH1])aa1,[SH]c1*:*c([SH])*:*1 +1813,"1,2 – Aminophenols","c([OH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[OH] +1814,"1,3 – Aminophenols","c([OH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[OH] +1815,"1,4 – Aminophenols","c1([OH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([OH])*:*1 +1816,"1,2 – Aminothiophenols","c([SH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[SH] +1817,"1,3 – Aminothiophenols","c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[SH] +1818,"1,4 – Aminothiophenols","c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([SH])*:*1 +1819,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C +1820,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C +1821,Carbonic acid esters,"[#1,#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*OC(=O)OC +1822,Phosphonic acid amides,[OX1]=[Pv5X4]([NX3])([#6])[!#6!$([SX2])],*P(C)(N)=O +1823,Aldehyde,[CX3H1](=O)[#6],C[CH]=O +1824,AliphaticEther,[!$(C=O);$([C&!a])][OX2&H0][!$(C=O);$([C&!a])],*O* +1825,AminoAcids,"[$([NX3,NX4+][CX4H]([*])[CX3](=[OX1])[O,N]),$([$([$([NX3H2,NX4H3+]),$([NX3H](C)(C))][CX4H2][CX3](=[OX1])[OX2H,OX1-,N])])]",* +1826,AromaticHalogen,"[$([a][F,Cl,I])]",* +1827,AromaticNGroups,"[$([a]N(~O)~O),$([a]N([#1])[*]),$([a]N([#1])[!#1])]",* +1828,AromaticSulphonicAcid,"[$([#16X4](=[OX1])(=[OX1])([a])[OX2H,OX1H0-]),$([#16X4+2]([OX1-])([OX1-])([a])[OX2H,OX1H0-])]",* +1829,AzoGroup,[$([!R&N]=[!R&N])],* +1830,CyanoGroupOnMoreThanEightAtomsChain,[N]#[C]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0],*~*~*~*~*~*~*~*~C#N +1831,Epoxide,[$(C1OC1)],* +1832,Esters,[#6][CX3](=O)[$([OX2H0]([#6])[#6])],*C(C)=O +1833,Formaldehyde,[CX3H2](=O),C=O +1834,Ketone,[C][C](=O)[C],CC(C)=O +1835,MoreThanTwoHydroxyOnAromaticRing,"[$([a&R]([OX2H])[a&R]([OX2H])),$([a&R]([OX2H])a[a&R]([OX2H])),$([a&R]([OX2H])aa[a&R]([OX2H]))]",* +1836,Nitrile,[C]#[N],C#N +1837,NNitroso,[$(NN=O)],* +1838,PyridineRing,[$(n1ccccc1)],* +1839,TerminalTertButyl,[$([C]([CH3])([CH3])([CH3])([*]))],* +1840,TertiaryAmine,[!R&NX3&H0],* +1841,TriazineRing,"[$(n1nnccc1),$(n1ncncc1),$(n1cncnc1)]",* +1842,Trifluoromethyl,[$([*]C(F)(F)F)],* +1843,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1 +1844,Phenoxazines,"[OX1,N]=[#6]1-,:[#6]=,:[#6]2-,:[#16X2,#8X2]-,:[#6]3=,:[#6]-,:[#6](=,:[#6]-,:[#6]=,:[#6]3-,:[#7]=,:[#6]2-,:[#6]=,:[#6]1)",*=C1C=CC2=NC3=CC=CC=C3*C2=C1 +1845,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1 +1846,Imidazotriazoles,"[c,n]1cnn2c([NH])cnc12",[NH]c1cnc2*cnn12 +1847,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21 +1848,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21 +1849,NCCN,"[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]-[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]",** +1850,Picolylamines_A,"[$([NX3][CH2]c1ncnc([NX3])c1),$([NX3][CH2]c1nccc([NX3])n1)]",* +1851,Picolylamines_B,"[$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]n([H,CH3])cc1),$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]ccn1[H,CH3])]",* +1852,Picolylamines_C,"c1cccnc1[CH2!R][NX3!R]([H,CH3])[CH2!R]",*N([CH2])[CH2]c1ccccn1 +1853,Bis-picolylamines,"[nv3X2]c([c,s,n])[CX4][NX3]([H,C])[CX4]c([c,s,n])[nv3X2,nv3X3H1]",*N(Cc(*)*)Cc(*)n +1854,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1 +1855,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1 +1856,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n +1857,Diarylmethanes,"[$(c1[nX2][c,n][c,n][c,n]1),$([cr6][nX2r6])][CX4H2!R][$(c2[nX2][c,n][c,n][c,n]2),$([cr6][nX2r6])]",*[CH2]* +1858,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12 +1859,Heterylamides_A,"[$([cr5][n,s;r5][n,o;r5]),$([cr5]([nr5])[s,o,n;r5])][Nv3X3H1!R][CX3!R](=[OX1])[$([cr5][nv3X2r5]),$(c1ncccc1),$(c1c([OX2][CH3])cccc1)]",*[NH]C(*)=O +1860,Heterylamides_B,"[$(c1nnc[o,n]1),$(c1nccs1)][Nv3X3H!R][C!R](=[OX1])[CX4!H0]([H,CX4])[SX2,n]cc",*[NH]C(=O)C(*)*cc +1861,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1 +1862,8-Quinolinols,"[H,C][OX2]c1c([CX4][NX3])ccc2cccnc21",*Oc1c(CN)ccc2cccnc12 +1863,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1 +1864,Perchloroquinone,"[OX1]=[CX3]1C([F,Cl,Br,I])=C([F,Cl,Br,I])[CX3](=[OX1])C([F,Cl,Br,I])=C1[F,Cl,Br,I]",*C1=C(*)C(=O)C(*)=C(*)C1=O +1865,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn +1866,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1 +1867,A3,"[OH][CX3](=[OX1])[#6]1-,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:1",O=C([OH])C1=CC=CC=*1 +1868,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1 +1869,B5,"[#6]1=,:[#6]-,:[#6]=,:[#6]([OH])-,:[#6]2=,:[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]2",[OH]C1=CC=CC2=C1*=CC=C2 +1870,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12 +1871,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12 +1872,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12 +1873,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1 +1874,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1 +1875,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1 +1876,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1 +1877,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1 +1878,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1 +1879,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1 +1880,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12 +1881,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12 +1882,"C10, C11","[CH3]c1nc([OH])cc([OH,CH3])n1",*c1cc([OH])nc([CH3])n1 +1883,"C10*, C11*","[CX4]c1nc([OH])cc([OH,CX4])n1",*c1cc([OH])nc(C)n1 +1884,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH] +1885,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S +1886,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH] +1887,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH] +1888,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S +1889,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C +1890,"E6, E8","O=[#6]1-,:[#7]([H,CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",*N1C=CC=C([OH])C1=O +1891,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH] +1892,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C +1893,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S +1894,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S +1895,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH] +1896,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH] +1897,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH] +1898,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH] +1899,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1 +1900,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1 +1901,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1 +1902,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1 +1903,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1 +1904,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1 +1905,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21 +1906,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1 +1907,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12 +1908,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH] +1909,"G9,G10","c1ccc(c(c1)[OH,SH])[OX2][CX4]",*c1ccccc1OC +1910,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH] +1911,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH] +1912,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH] +1913,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH] +1914,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH] +1915,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1 +1916,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1 +1917,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1 +1918,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1 +1919,H8 - H12,"C[CX3](=[OX1])[CX4!H0]([H,CX4,Cl])[CX3](=[OX1])C",*C(C(C)=O)C(C)=O +1920,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O +1921,Salts_C,"[!#1!#2!#5!#6!#7!#8!#9!#10!#14!#15!#16!#17!#18!#32!#33!#34!#35!#36!#51!#52!#53!#54!#84!#85!#86]~[#6,#7,#8,#16]",*~* +1922,Pt,[Pt],[Pt] +1923,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +1924,β-lactones and γ- sultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +1925,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O +1926,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +1927,Heterocyclic Polycyclic Aromatic Hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +1928,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1929,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1 +1930,Azafluorenones,"[OX1,SX1]=[#6X3]1c2c([nX2][cX3,nX2,nX3][cX3,nX2,nX3][cX3,nX2,nX3]2)[c,n]2c1[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])]2",*=C1c2cccc*2c2n*:*:*c21 +1931,Cyanothioazinones,"[SX1]=[#6X3]1-,:[#7X3H1]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#7X2,#6X3!$([#6X3]=[A])]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#6X3]1([CX2]#[NX1])",N#CC1=**=*[NH]C1=S +1932,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1 +1933,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1934,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1 +1935,Benzoxathiolones,"[$([#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]),$([#8]1-,:[#6](-,:[#16]c4ccc(cc14)[#7,#8])=[OX1,SX1])]",* +1936,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21 +1937,Pyrazolones,"[#7X2]1=,:[#6X3]-,:[#6X3](-,:[#6X3](-,:[#7X3]1)=[SX1,OX1])=,:[#6X3H1](-,:[#7X3H1])",*=C1NN=CC1=[CH][NH] +1938,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1 +1939,Pyrimidinones_A,"[OX1,SX1]=[#6X3]1[#7X3](-,:[#7X2]=,:[#6X3][NX3H1][#6])-,:[cX3!$([#6X3]=[A])]=,:[#7X2]-,:[cX3!$([#6X3]=[A])]=,:[cX3!$([#6X3]=[A])]1",*=C1c=cN=cN1N=C[NH]C +1940,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12 +1941,Pyrimidinones_C,"[OX1,SX1]=[#6X3]1[#7X3]-,:[#6X3!$([#6X3]=[A])](-[NX3])=,:[#7X2]-,:[#6X3]2([nX2][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])]c12)",*=C1NC(N)=NC2nCCCc21 +1942,Pyrimidinodiones,"[#6X3]1(=[OX1,SX1])-,:[#7X3H1]-,:[#6X3](=[OX1,SX1])-,:[#7X3,#7X2]~[#6X3]([#7X2,#7X3;R1])-,:[#6X3]1[sX2r5R1,nX2r5R1,$([nx2r6R1]([cX3])[cX3])]",*C1C(*)C(=*)[NH]C(=*)*~1 +1943,Thienopyrimidinone_A,"[OX1,SX1]=[#6X3]1-,:[#7X3H1]-,:[#6X4]-,:[#7X3H1]-,:[#6]2-,:[#16X2,#8X2]-,:[#6]3[CX4][NX3,CX4][CX4][CX4]-,:[#6]3-,:[#6]12",*=C1[NH]C[NH]C2*C3C*CCC3C21 +1944,Piperazinediones,"[#7X3]1-,:[#6X3](=[OX1,SX1])-,:[#6X3](=[OX1,SX1])-,:[NX3]-,:[#6X3]2[cX3!$([#6X3]=[A])][cX3]([NX3H1][CX3]=[OX1])[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3]12",*=C1NC2cc([NH]C=O)ccc2NC1=* +1945,4-Heteryl-thiazoles,"s1[c,nX2][c,nX2](-c(c)[nX2,nX3,sX2])[nX2]c1",*c(c)-*1:*scn1 +1946,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1 +1947,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH] +1948,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1 +1949,Cyanothioethers,"[NX1]#[CX2][CX4H2][SX2]c1n[c,n][c,n][c,n]n1",N#C[CH2]Sc1n*:*:*n1 +1950,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1 +1951,Fused azacycles_A,"[nX2R1][c,n;R2]1[c,n;R2]([c,n;R1])[c,n][c,n][c,n;R2]([c,n;R1])[nR2]1[nX2R1]",*:*1:*:*:*(:*)n(n)*:1n +1952,Fused azacycles_B,"[NX1]#[CX2]c1[c!$([#6]=[OX1])]n[n,c!$([#6]=[OX1])]2[c,n][c!$([#6]=[OX1])][c!$([#6]=[OX1])]nc12",N#Cc1cn*2:*ccnc21 +1953,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12 +1954,Arylethanolamines,"[$([NX3]([CX4,H])([CX4,H])[CX4]),$([OX2]([H,CX4])[CX4])][CX4!H0][CX4H2][NX3H1]c[nX2r6R1][nX2,nX3][nX2,cX3;R1][cX3,nX2][cX3,nX2][sX2,cX3][cX3]",*C[CH2][NH]cn*:*:*:*:*c +1955,Azaspironones,"[X4;R2]12(-,:;@[#6X3]-,:;@[#6X3]-,:;@[#7X3]-,:;@[#6X3]-,:;@1)-,:;@[#16X2]-,:;@[#6X3]=,:;@[#7X2]-,:;@[#7X3]-,:;@2",C1C*2(CN1)NN=CS2 +1956,Radical,[#16;X3v3+0],S +1957,N⋯X halogen bonding,"N[F,Cl,Br,I]",*N +1958,Charged atoms,"[+,-]",* +1959,Benzyl Imidazole scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*-,=*c:3:c:c:c:c:c:3",*(*c1ccccc1)*1:*:*2:*c*c*:2:*:1 +1960,6-Phenyl Napthaline type scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s][c,n,o,s]2)*~*c:3:c:c:c:c:c:3",*(~*c1ccccc1)*1:*:*:*2:*c*c*:2:*:1 +1961,2-(2-(1H-pyrrol-2-yl)ethyl)-1H-benzoimidazole scaffold,"[c,n]:1:c:c2:c(:[c,n]:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*~*c3ccc*3",*(~*c1ccc*1)*1:*c2*c*cc2*:1 +1962,2 - Olefin group,"[$([CX3H2]=[CX3H1]),$([CX3H1]=[CX3H1]),$([CX3H2]=[CX3H0]),$([CX3H1]=[CX3H0]),$([CX3H0]=[CX3H0])]",* +1963,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +1964,6 - Methanol,[CX4H3][OX2H1],[CH3][OH] +1965,7 - Water,[OX2H2],O +1966,9 - Сarbonyl,"[$([CX4H3][CX3](=[OX1])[#6]),$([CX4H2][CX3H0](=[OX1])[#6])]",* +1967,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O +1968,11 - Acetate group,"[$([CX4H3][CX3](=[OX1])[OX2][#6]),$([CX4H2][CX3](=[OX1])[OX2][#6])]",* +1969,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +1970,14 - Primary amine,"[$([CX4H3][NX3H2]),$([CX4H2][NX3H2]),$([CX4H1][NX3H2])]",* +1971,16 - Tertiary amine,"[$([CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]),$([CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6])]",* +1972,19 - CCN,"[$([CX4H3][CX2]#[NX1]),$([CX4H2][CX2]#[NX1])]",* +1973,20 - COOH,"[$([CX3H0](=[OX1])[OX2H1]),$([CX3H1](=[OX1])[OX2H1])]",* +1974,21 - CCl,"[$([CX4H2!$([CX4H2](Cl)Cl)]Cl),$([CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl]),$([CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl])]",* +1975,22 - CCl2,"[$([CX4H2]([Cl])[Cl]),$([CX4H1]([!Cl!F])([Cl])[Cl]),$([CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F])]",* +1976,23 - CCl3,"[$([CX4H1]([Cl])([Cl])[Cl]),$([CX4H0]([!Cl!F])([Cl])([Cl])[Cl])]",* +1977,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +1978,26 - CNO2,"[$([CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)])]",* +1979,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S +1980,29 - CH3SH,"[$([CX4H3][SX2H1]),$([CX4H2][SX2H1])]",* +1981,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +1982,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +1983,32 - Iodo compounds,[I],I +1984,33 - Bromo compounds,[Br!$([Br][cR])],Br +1985,34 - Carbon triple bond,"[$([CX2H1]#[CX2H0]),$([CX2H0]#[CX2H0])]",* +1986,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +1987,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +1988,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl +1989,39 - DMF,"[$([CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3]),$([CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2])]",* +1990,40 - CF2,"[$([CX4](F)(F)(F)[!Cl!F]),$([CX4](F)(F)([!F!Cl!H])([!F!Cl!H])),$([CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]))]",* +1991,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +1992,42 - SiH2,"[$([SiX4H3]),$([SiX4H2]([!$([OX2])])([!$([OX2])])),$([SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])])),$([SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]))]",* +1993,43 - SiO,"[$([SiX4H2][OX2]),$([SiX4H1][OX2]),$([SiX4H0][OX2])]",* +1994,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +1995,47 - OCCOH,"[$([OX2H0!R][CX4H2][CX4H2][OX2H1]),$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +1996,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +1997,52 - Sulphones,"[$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2]),$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1])]",* +1998,53 - Oxides,"[$([CX4H2]1[OX2][CX4H2]1),$([CX4H2]1[OX2][CX4H1]1),$([CX4H2]1[OX2][CX4H0]1),$([CX4H1]1[OX2][CX4H1]1),$([CX4H1]1[OX2][CX4H0]1),$([CX4H0]1[OX2][CX4H0]1)]",* +1999,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2000,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C +2001,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH] +2002,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C +2003,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C +2004,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C +2005,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c +2006,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +2007,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH] +2008,17 - H2O (7 - Water),[OX2H2],O +2009,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O +2010,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O +2011,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O +2012,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O +2013,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O +2014,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +2015,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3] +2016,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2] +2017,28 - THF (13 - Ether),[OX2R!r3!$([OX2]C=[OX1])!$([OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1)]([R])[CX4H2R],*O[CH2] +2018,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2] +2019,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2] +2020,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2] +2021,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3] +2022,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2] +2023,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH] +2024,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3] +2025,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2] +2026,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1 +2027,39 - C5H4N (18 - Pyridine),"[$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]:[cX3H1]1)]",* +2028,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N +2029,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N +2030,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH] +2031,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH] +2032,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl +2033,46 - CHCl (21 - CCl),[CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl],*[CH](*)Cl +2034,47 - CCl (21 - CCl),[CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl],*C(*)(*)Cl +2035,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl +2036,49 - CHCl2 (22 - CCl2),[CX4H1]([!Cl!F])([Cl])[Cl],*[CH](Cl)Cl +2037,50 - CCl2 (22 - CCl2),[CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F],*C(*)(Cl)Cl +2038,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl +2039,52 - CCl3 (23 - CCl3),[CX4H0]([!Cl!F])([Cl])([Cl])[Cl],*C(Cl)(Cl)Cl +2040,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +2041,55 - CH3NO2 (26 - CNO2),"[CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH3] +2042,56 - CH2NO2 (26 - CNO2),"[CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH2] +2043,57 - CHNO2 (26 - CNO2),"[CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH] +2044,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S +2045,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH] +2046,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH] +2047,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +2048,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +2049,64 - I (32 - Iodo compounds),[I],I +2050,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br +2051,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C +2052,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C +2053,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +2054,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +2055,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl +2056,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O +2057,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O +2058,74 - CF3 (40 - CF2),[CX4](F)(F)(F)[!Cl!F],*C(F)(F)F +2059,75 - CF2 (40 - CF2),[CX4](F)(F)([!F!Cl!H])([!F!Cl!H]),*C(*)(F)F +2060,76 - CF (40 - CF2),[CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]),*C(*)(*)F +2061,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +2062,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3] +2063,79 - SiH2 (42 - SiH2),[SiX4H2]([!$([OX2])])([!$([OX2])]),*[SiH2]* +2064,80 - SiH (42 - SiH2),[SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[SiH](*)* +2065,81 - Si (42 - SiH2),[SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[Si](*)(*)* +2066,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2] +2067,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH] +2068,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si] +2069,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +2070,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl +2071,87 - CCl2F (45 - CClF),[CX4H0]([Cl])([Cl])([F])[!Cl!F],*C(F)(Cl)Cl +2072,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl +2073,89 - HCClF (45 - CClF),[CX4H1](Cl)(F)([!F!Cl]),*[CH](F)Cl +2074,90 - CClF2 (45 - CClF),[CX4H0](Cl)(F)(F)[!Cl!F],*C(F)(F)Cl +2075,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl +2076,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl +2077,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl +2078,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O +2079,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O +2080,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O +2081,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O +2082,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O +2083,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O +2084,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH] +2085,101 - C2H4O2 (47 - OCCOH),"[$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +2086,102 - CH3S (48 - CH2S),[CX4H3][SX2H0][*],*S[CH3] +2087,103 - CH2S (48 - CH2S),[CX4H2][SX2H0!$([SX2H0]([CX4H2])[CX4H3])][*],*S[CH2] +2088,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +2089,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1 +2090,107 - C4H3S (50 - Thiophene),"[$([#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H0]=,:1),$([#6X3H1]1-,:[#16X2]-,:[#6X3H0]=,:[#6X3H1]-,:[#6X3H1]=,:1)]",* +2091,109 - NCO (51 - NCO),[*][NX2]=[CX2]=[OX1],*N=C=O +2092,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O +2093,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O +2094,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1 +2095,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1 +2096,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1 +2097,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1 +2098,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1 +2099,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1 +2100,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2101,phosphorodithionate,[$([SX2H0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2102,"O,O-diethylphosphorodithionate",CCOP(=S)(OCC)SC([*:1]),CCOP(=S)(OCC)SC[*:1] +2103,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O +2104,"O,O-dimethylphosphoryl",COP(=O)(O([*:1]))OC,COP(=O)(OC)O[*:1] +2105,phosphorothionate,[$([OH0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2106,diethylphosphorothionate,CCOP(=S)(O([*:1]))OCC,CCOP(=S)(OCC)O[*:1] +2107,O-phenyl phenylphosphonothioate,S=P(O([*:1]))(Oc1ccc([*:1])cc1)c1ccccc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])c1ccccc1 +2108,O-phenyl phosphonothioate,S=P(O([*:1]))(O([*:1]))Oc1ccc([*:1])cc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])O[*:1] +2109,carbamate,[$(N([!H])C(=O)[OH0])]C(=O)[OH0],*C(O)=O +2110,"2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-(aminosulfanyl)-N-methylcarbamate",CN(SN([*:1])([*:1]))C(=O)Oc1cccc2CC(C)(C)Oc12,CN(SN([*:1])[*:1])C(=O)Oc1cccc2c1OC(C)(C)C2 +2111,methyl(propoxysulfanyl) carbamate,CN(SOCCC([*:1]))C(=O)O([*:1]),CN(SOCCC[*:1])C(=O)O[*:1] +2112,phenyl carbamate,O=C(N([*:1]))Oc1ccccc([*:1])1,O=C(N[*:1])Oc1ccccc1[*:1] +2113,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C +2114,dimethylcarbamate,CN(C)C(=O)O([*:1]),CN(C)C(=O)O[*:1] +2115,barbiturates,*C1(*)[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]1=O,*C1(*)C(=O)NC(=O)NC1=O +2116,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1 +2117,Phenothiazine,*-[#7]-1-c2ccccc2-[#16]-c2ccccc-12,*N1c2ccccc2Sc2ccccc21 +2118,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1 +2119,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1 +2120,"2,4-dichloro-benzene-1,3-dicarbonitrile",N#Cc1c([*:1])c([*:1])c(Cl)c(C#N)c1Cl,N#Cc1c(Cl)c(C#N)c([*:1])c([*:1])c1Cl +2121,R1 - Reactive alkyl halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2122,R2 - Acid halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2123,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O +2124,R4 - Sulphate esters,"COS(=O)O[C,c]",*OS(=O)OC +2125,R5 - Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2126,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O +2127,R7 - Peroxides,OO,OO +2128,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2129,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1 +2130,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O +2131,R11 - Isocyanates & Isothiocyanantes,"N=C=[S,O]",*=C=N +2132,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2133,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S +2134,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2135,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-] +2136,R16 - beta carbonyl quaternary Nitrogen,"C(=O)C[N+,n+]",*CC=O +2137,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O +2138,"R18 - Quaternary C,Cl,I,P or S","[C+,Cl+,I+,P+,S+]",* +2139,R19 - Phosphoranes,C=P,C=P +2140,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl +2141,R21 - Nitroso,[N&D2](=O),N=O +2142,R22 - P/S Halides,"[P,S][Cl,Br,F,I]",** +2143,R23 - Carbodiumide,N=C=N,N=C=N +2144,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+] +2145,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2146,R26 - Cyanohydrins,N#CC[OH],N#CC[OH] +2147,R27 - Acyl cyanides,N#CC(=O),N#CC=O +2148,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O +2149,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2150,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N +2151,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2152,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC +2153,I2 - Compounds with 4 or more acidic groups,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2154,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2155,I4 - Disulphides,SS,SS +2156,I5 - Thiols,[SH],[SH] +2157,"I6 - Epoxides, Thioepoxides, Aziridines","C1[O,S,N]C1",*1CC1 +2158,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2159,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2160,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2161,I10 - Thiocyanate,SC#N,N#CS +2162,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+] +2163,I12 - Thioesters,"C[O,S;R0][C;R0](=S)",C*C=S +2164,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N +2165,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1 +2166,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2167,I16 - Betalactams,N1CCC1=O,O=C1CCN1 +2168,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1 +2169,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2170,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2171,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2172,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2173,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2174,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1 +2175,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2176,"A1 - e.g., carboxylic acid","[OH1][P,C,S](=O)",O=*[OH] +2177,"A2 - e.g.,imide","[NH1]([P,S]=O)([P,S]=O)",O=*[NH]*=O +2178,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1 +2179,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1 +2180,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1 +2181,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O +2182,A8,[nH1]1ncoc1=O,O=c1[nH]nco1 +2183,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1 +2184,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1 +2185,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1 +2186,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1 +2187,A13,[nH1]1occc1=O,O=c1cco[nH]1 +2188,A14,[OH1]c1oncc1,[OH]c1ccno1 +2189,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1 +2190,A16 - tetrazole,[nH1]nnn,nnn[nH] +2191,A17,[nH1](n)nn,nn[nH]n +2192,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1 +2193,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1 +2194,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1 +2195,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1 +2196,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1 +2197,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1 +2198,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1 +2199,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21 +2200,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21 +2201,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21 +2202,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH] +2203,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1 +2204,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH] +2205,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F +2206,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O +2207,A33 - phenol,"[OH1]c1c[c,n]ccc1",[OH]c1c*ccc1 +2208,B1 - primary amine,[NH2][CX4],C[NH2] +2209,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C +2210,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C +2211,B4SUB,"[C,c](=N)N",N*=N +2212,B5EXC,"[C,c](=N)N[C,S](=O)",N=*N*=O +2213,B6,"[$([C,c](=N)N);!$([C,c](=N)N[C,S](=O))]",* +2214,B7EXC,n(:c)(:c):a,*n(c)c +2215,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1 +2216,B8EXC,"[N,n;+1]",* +2217,B9,"[$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]",* +2218,E1 - alkyl and aryl ketones and aldehydes,"[C;H1](=[O,S])[C,c]",*C=* +2219,"E2 - e.g., carboxylic esters","[C,P;H1](=[O,S])[O,S]",**=* +2220,"E3 - e.g., carbonates","[C](=O)([C,c,O,S])[C,c,O,S]",*C(*)=O +2221,E4EXC,C(=O)[OH1],O=C[OH] +2222,E5EXC,C(=O)[SH1],O=C[SH] +2223,E6,"C(=[O,S])(N)Oc",*=C(N)Oc +2224,"E7 - e.g., aryl carbamates","C1(=O)NS(=O)(=O)[C,c]=,:[C,c]1",O=C1*=*S(=O)(=O)N1 +2225,E8SUB,"P(=O)[O,S]",*P=O +2226,E9EXC,P[OH1],[OH]P +2227,E10,"[$(P(=O)[O,S]);!$(P[OH1])]",* +2228,E11,c(=O)(~c)~c,c~c(~c)=O +2229,E12EXC,"[$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)]",* +2230,E12,"[$(c(=O)(~c)~c);!$([$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)])]",* +2231,E13 - imides,C(=O)-N-C=O,O=CNC=O +2232,N1 - pimary amines,[NX3H2][CX4],C[NH2] +2233,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C +2234,N4EXC,"N=[O,C,N,S]",*=N +2235,N5EXC,"N-[C,c,N]=[C,c,N,n,O,S]",*=*N +2236,N6,"[OH1][C,c,N;!$(C=O)]",*[OH] +2237,N7EXC,[OH1]C=C,C=C[OH] +2238,N8EXC,"[OH1]NC=[O,S]",*=CN[OH] +2239,N9,"[$([NX3H2]!:c),$([NX3H1]([CX4])!:c),$([NX3H0]([CX4])([CX4])!:c)]",* +2240,NUC,"[$([NH2][CX4]),$([NH]([CX4])[CX4]),$([OH1][C,c,N;!$(C=O)]),$([$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]);!$(N=[O,C,N,S]);!$(N-[C,c,N]=[C,c,N,n,O,S]);!$([OH1]C=C);!$([OH1]NC=[O,S])]",* +2241,> 2 ester groups,"C(=O)O[C,H1].C(=O)O[C,H1].C(=O)O[C,H1]",*OC=O.*OC=O.*OC=O +2242,2-halo pyridine,"n1c([F,Cl,Br,I])cccc1",*c1ccccn1 +2243,Acid halide,"C(=O)[Cl,Br,I,F]",*C=O +2244,Acyclic C=C-O,C=[C!r]O,C=CO +2245,Acyl cyanide,N#CC(=O),N#CC=O +2246,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O +2247,Aliphatic long chain,[R0;D2][R0;D2][R0;D2][R0;D2],**** +2248,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1 +2249,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1 +2250,Azido group,N=[N+]=[N-],[N-]=[N+]=N +2251,Azo group,N=N,N=N +2252,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1 +2253,Benzidine,"[cR2]1[cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2][cR2]1[cR2]2[cR2][cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2]2",*c1ccc(c2ccc(*)cc2)cc1 +2254,Betaketo/anhydride,"[C,c](=O)[CX4,CR0X3,O][C,c](=O)",O=***=O +2255,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2256,Carbo cation/anion,"[C+,c+,C-,c-]",* +2257,Catechol,"c1c([OH])c([OH,NH2,NH])ccc1",*c1ccccc1[OH] +2258,Charged oxygen or sulfur atoms,"[O+,o+,S+,s+]",* +2259,Chinone (1),"C1(=[O,N])C=CC(=[O,N])C=C1",*=C1C=CC(=*)C=C1 +2260,Chinone (2),"C1(=[O,N])C(=[O,N])C=CC=C1",*=C1C=CC=CC1=* +2261,Conjugated nitrile group,C=[C!r]C#N,C=CC#N +2262,Crown ether,"[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]",*~C~C~*~C~C~* +2263,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1 +2264,Cyanamide,N[CH2]C#N,N[CH2]C#N +2265,Cyanate/aminonitrile/thiocyanate,"[N,O,S]C#N",*C#N +2266,Cyanohydrins,N#CC[OH],N#CC[OH] +2267,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1 +2268,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1 +2269,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1 +2270,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1 +2271,Diaminobenzene (1),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])c([N+R0,NX3R0,nX3R0])[cR2][cR2]1",*c1ccccc1* +2272,Diaminobenzene (2),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2]c([N+R0,NX3R0,nX3R0])[cR2]1",*c1cccc(*)c1 +2273,Diaminobenzene (3),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2][cR2]c1([N+R0,NX3R0,nX3R0])",*c1ccc(*)cc1 +2274,Diazo group,[N!R]=[N!R],N=N +2275,Diketo group,"[C,c](=O)[C,c](=O)",O=**=O +2276,Disulphide,SS,SS +2277,Enamine,[CX3R0][NX3R0],CN +2278,Ester of HOBT,C(=O)Onnn,nnnOC=O +2279,Four member lactones,C1(=O)OCC1,O=C1CCO1 +2280,Halogenated ring (1),"c1cc([Cl,Br,I,F])cc([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1ccc(*)c(*)c1 +2281,Halogenated ring (2),"c1ccc([Cl,Br,I,F])c([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1cccc(*)c1* +2282,Heavy metal,"[Hg,Fe,As,Sb,Zn,Se,se,Te,B,Si]",* +2283,Het-c-het not in ring,"[NX3R0,NX4R0,OR0,SX2R0][CX4][NX3R0,NX4R0,OR0,SX2R0]",*C* +2284,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1 +2285,Hydroxamic acid,C(=O)N[OH],O=CN[OH] +2286,Imine,C=[N!R],C=N +2287,Isolated alkene,"[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]=[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]",*=* +2288,Ketene,C=C=O,C=C=O +2289,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1 +2290,Michael acceptor (1),"C=!@CC=[O,S]",*=CC=C +2291,Michael acceptor (2),"[$([CH]),$(CC)]#CC(=O)[C,c]",*C(=O)C#* +2292,Michael acceptor (3),"[$([CH]),$(CC)]#CS(=O)(=O)[C,c]",*S(=O)(=O)C#* +2293,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O +2294,Michael acceptor (5),"[$([CH]),$(CC)]#CC(=O)O[C,c]",*OC(=O)C#* +2295,N oxide,"[NX4,nX3][OX1]",*O +2296,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1 +2297,N-c-halo,"NC[F,Cl,Br,I]",*CN +2298,N-halo,"[NX3,NX4][F,Cl,Br,I]",** +2299,N-hydroxylpyridine,n[OH],n[OH] +2300,Nitro group,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]",* +2301,N-nitroso,[#7]-N=O,NN=O +2302,Oxime (1),"[C,c]=N[OH]",*=N[OH] +2303,Oxime (2),"[C,c]=NOC=O",*=NOC=O +2304,Oxygen-nitrogen single bond,"[OR0,NR0][OR0,NR0]",** +2305,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F +2306,Peroxide,OO,OO +2307,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1 +2308,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1 +2309,Phosphor,P,P +2310,Phthalimide,"[cR,CR]~C(=O)NC(=O)~[cR,CR]",*~C(=O)NC(~*)=O +2311,Polycyclic aromatic hydrocarbon (1),"a1aa2a3a(a1)[a,A]=,:[a,A]-,:[a,A]=,:[a,A]3A=AA2",*1*=**2:*3:*1:*:*:*:*:3:*=**=2 +2312,Polycyclic aromatichydrocarbon (2),a21aa3a(aa1aaaa2)aaaa3,*1:*:*:*2:*:*3:*:*:*:*:*:3:*:*:2:*:1 +2313,Polycyclic aromatichydrocarbon (3),a31a(a2a(aa1)aaaa2)aaaa3,*1:*:*:*2:*(:*:1):*:*:*1:*:*:*:*:*:1:2 +2314,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C +2315,Quaternary nitrogen (1),"[s,S,c,C,n,N,o,O]~[nX3+,NX4+](~[s,S,c,C,n,N])~[s,S,c,C,n,N]",*~*(~*)~* +2316,Quaternary nitrogen (2),"[s,S,c,C,n,N,o,O]~[n+,N+](~[s,S,c,C,n,N,o,O])(~[s,S,c,C,n,N,o,O])~[s,S,c,C,n,N,o,O]",*~*(~*)(~*)~* +2317,Quaternary nitrogen (3),[*]=[N+]=[*],*=[N+]=* +2318,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2319,Silicon halogen,"[Si][F,Cl,Br,I]",*[Si] +2320,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1 +2321,Sulfinic acid,"[SX3](=O)[O-,OH]",*S=O +2322,Sulfonic acid,"[C,c]S(=O)(=O)O[C,c]",*OS(*)(=O)=O +2323,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2324,Sulfur oxygen single bond,[SX2]O,OS +2325,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-] +2326,Sulphur nitrogen single bond,[SX2H0][N],NS +2327,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1 +2328,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1 +2329,Thiocarbonyl group,"[C,c]=S",*=S +2330,Thiol (1),[S-],[SH-] +2331,Thiol (2),[SH],[SH] +2332,Three-membered heterocycle,"*1[O,S,N]*1",*1**1 +2333,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2334,Triphenyl methylsilyl,"[SiR0,CR0](c1ccccc1)(c2ccccc2)(c3ccccc3)",c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2335,Triple bond,C#C,C#C +2336,Aromatic NO2,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-c(:*):*",*c(:*):* +2337,Deuterium,[2H],[2HH] +2338,C13,[13#6],[13CH4] +2339,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1 +2340,"Si,B,Se atoms","[Si,B,Se]",* +2341,Hetero imides,[!#6]-[CH2]-N1C(=O)CCC(=O)1,*CN1C(=O)CCC1=O +2342,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O +2343,Acyclic imines,"C-!@[NX2]=[C!R,#1]-C",C*=NC +2344,Alkyl esters of S or P,"[S,P](=O)OC",CO*=O +2345,Ugly P compounds,"P(=[O,S])[C,N]([C,N])[C,N]",**(*)P=* +2346,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN +2347,Acyclic N-C-N,N-!@[CX4]-!@N,NCN +2348,Acyclic N-S,N-!@[SX2]-*,*SN +2349,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O +2350,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O +2351,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1 +2352,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O +2353,Acyl halide,"O=C-[F,Cl,Br,I]",*C=O +2354,Alpha halo carbonyl,"O=C-C-[F,Cl,Br,I]",*CC=O +2355,Sufonyl halide,"S(=O)(=O)-[F,Cl,Br,I]",*[SH](=O)=O +2356,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N +2357,26,N-C(=S)-N,NC(N)=S +2358,Terminal vinyl,[CH2D1]=[CD2]-!@*,*C=C +2359,28,S=P~*,*~P=S +2360,Thio cyanates,S-C#N,N#CS +2361,Thionyl,[Sv4](=O)(-!@[!#1])-!@[!#1],*S(*)=O +2362,N-Haloamines,"N-[F,Cl,Br,I]",*N +2363,N-C-Hal or cyano methyl,"N-C-[F,Cl,Br,I,$(C#N)]",*CN +2364,Alpha beta-unsaturated ketones; center of Michael reactivity,"[$(C#N),$(N(~O)~O),$(C=O),$(S(=O)=O),$(C(F)(F)F),Cl][C!H0]=[C!H0]",*C=C +2365,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O +2366,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2] +2367,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2] +2368,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N +2369,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO +2370,42,S-S,SS +2371,43,O~O,O~O +2372,Aziridine-like N in 3-membered ring,N~1~*~*1,*1~*~N~1 +2373,Aryl iodide,I-c:*,*:cI +2374,Aryl bromide,Br-c:*,*:cBr +2375,Multiple aromatic rings,a1aaa2a(a1)aaa(a2):a,*:*1:*:*:*2:*:*:*:*:*:2:*:1 +2376,S/PO3 groups,"[P,S](~O)(~O)~O",O~*(~O)~O +2377,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3 +2378,Too many cyano groups (>1),C#N.C#N,C#N.C#N +2379,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH] +2380,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O +2381,Chlorates,Cl~O,O~Cl +2382,High halogen content (>3),"[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I]",*.*.*.* +2383,Filter1_2_halo_ether,"[Cl,Br,I][CX4][CX4][$([O,S,N]*),Cl,Br,I]",*CC* +2384,Filter2_acyl_phosphyl_sulfonyl_halide,"[C,S,P](=O)[F,Cl,Br,I]",**=O +2385,Filter3_allyl_halide,"[F,Cl,Br,I][CX4]C=C",*CC=C +2386,Filter4_alpha_halo_carbonyl,"[Br,Cl,I][C!H0]C=[O,S]",*CC=* +2387,Filter5_azo,"[!#7,#1]~[NX2R0]=[NX2R0]~[!#7,#1]",*~N=N~* +2388,Filter6_benzyl_halide,"[Br,Cl,I][CX4]c",*Cc +2389,Filter7_diazo,[!#7]~[NX2]~[NX1],*~N~N +2390,Filter8_thio_isocyanat_diimin,"N=C=[N,O,P,S]",*=C=N +2391,Filter9_metal,"[!#1!#6!#7!#8!#9!#15!#16!#17]~[*,#1]",*~* +2392,Filter10_Terminal_vinyl,"[CH2]=[CH][N,O,P,S;R0]",*[CH]=C +2393,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O +2394,Filter12_nitroso,"[*,#1]~[NX2]~[OX1]",*~N~O +2395,Filter13_PS_double_bond,"S=P~[*,#1]",*~P=S +2396,Filter14_thio_oxopyrylium_salt,"c1ccc[s,o;X2]c1",*1ccccc1 +2397,Filter15_thiosulfate,[SX4](~S)(~O)(~O)~*,*~S(~O)(~O)~S +2398,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C +2399,Filter17_trialkyl_phosphin2,[PX4](~[!O!S])([#6])([#6])[#6],*~P(C)(C)C +2400,Filter18_oxime_ester,"[!#7,#1]C=NO[C,S,P](=O)*",*C=NO*(*)=O +2401,Filter19_hydroxyimide_ester,O=C[NX3](C=O)OC(=O)*,*C(=O)ON(C=O)C=O +2402,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN +2403,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH] +2404,Filter22_sulfonium_salt,*[SX3](*)*,*S(*)* +2405,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O +2406,Filter24_react_imide,"*C([F,Cl,Br,I,$(OS(=O)(=O)*)])=[NX2]*",*N=C(*)* +2407,Filter25_sulfonyl_halide,"*S(=O)(=O)[F,Cl,Br,I]",*S(*)(=O)=O +2408,Filter26_alkyl_halide,"AA[CH2][F,Cl,Br,I,$(OS(=O)(=O)*)]",**[CH2]* +2409,Filter27_anhydride,"*[C,S](=O)O[C,S](=O)*",**(=O)O*(*)=O +2410,Filter28_halo_pyrimidine,"c1nc(ncc1)[Br,I]",*c1ncccn1 +2411,Filter29_thioester,"CC(=[OX1,SX1,NH])[SX2][*,#1]",*SC(=*)C +2412,Filter30_beta_halo_carbonyl,"[#6,#1]C(=O)CC[Br,I]",*CCC(*)=O +2413,Filter31_SO_bond,"[*,#1][SX2R0]O[*,#1]",*OS* +2414,Filter32_OO_bond,"[*,#1][OR0]O[*,#1]",*OO* +2415,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3] +2416,Filter34_isotope,"[2#1,3#1,13C,14C,15N,125I,23F,22Na,32P,33P,35S,45Ca,57Co,103Ru,141Ce]",* +2417,Filter35_PP_bond,P-P,PP +2418,Filter36_SS_double_bond,S=S,S=S +2419,Filter37_silicate,[Si]~O,O~[SiH4] +2420,Filter38_aldehyde,O=[CH]*,*[CH]=O +2421,Filter39_imine,C[CR0]=[NR0][*!O],*N=CC +2422,Filter40_epoxide_aziridine,"C1C[N,S,O]1",*1CC1 +2423,Filter41_12_dicarbonyl,*C(=O)C(=O)*,*C(=O)C(*)=O +2424,Filter42_12_dicarbonyl_tautomer,[*!$(C[OH])]=C([OH])C(=O)*,*C(=O)C(=*)[OH] +2425,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O +2426,Filter44_michael_acceptor2,"[#6,#1,OH0][C!$(C1(=O)C=CC(=O)C=C1)](=O)C=[C!$(C[Nv3X3,OH])]",*C(=O)C=C +2427,Filter45_allyl_halide2,"[Br,Cl,I][CX4]C=[C,N,P]",*CC=* +2428,Filter46_nhalide,"N[F,Cl,Br,I]",*N +2429,Filter47_SO2F,O=S(=O)(*)F,*S(=O)(=O)F +2430,Filter48_FOSO,O=S(*)OF,*S(=O)OF +2431,Filter49_halogen,"[*,#1]~[F,Cl,Br,I]~[*,#1]",*~*~* +2432,Filter50_grignard,"C[Mg][F,Cl,Br,I]",*[Mg]C +2433,Filter51_PN3,N[PX3](N)N,NP(N)N +2434,Filter52_NC_haloamine,"NC[F,Cl,Br,I]",*CN +2435,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +2436,Filter56_SS_bond,S-S,SS +2437,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1 +2438,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1 +2439,Filter59_phoshorous_ylide,C=P,C=P +2440,Filter60_Acyclic_N-S,N!@[SX2],N~S +2441,Filter61_phosphor_halide_and_P_S_bond,"[#15]~[F,Cl,Br,I,#16]",*~P +2442,Filter62_oxo_thio_halide,"[O,S]~[Cl,Br,I]",*~* +2443,Filter63_polyaromatic,a1aaaa2ccc3ccccc3c12,*1:*:*c2*(:*:1)ccc1ccccc12 +2444,Filter64_halo_ketone_sulfone,"[#6][C,S](=[O,S])C[F,Cl,Br,I]",*C*(=*)C +2445,Filter65_alkyl_sulfonate,"[#6][P,S](~[OX1])(~[OX1])O[C!H0]",CO*(C)(~O)~O +2446,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F +2447,Filter67_S_or_O_C_triplebond_N,"[O,S]C#N",*C#N +2448,Filter68_anthracene_acridine,a1aaac2cc3ccccc3cc12,*1:*:*c2cc3ccccc3cc2*:1 +2449,Filter69_thio_carbonate,"[O,S]C(=[O,S])[O,S]",*C(*)=* +2450,Filter70_AlkylCN2,*(C#N)C#N,N#C*C#N +2451,Filter71_thio_anhydride,"*C(=[O,S])[O,S]C(=[O,S])*",*C(=*)*C(*)=* +2452,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH] +2453,Filter73_thio_ketone,CC(=S)C,CC(C)=S +2454,Filter74_thiol,*[SX2H],*[SH] +2455,Filter75_alkyl_Br_I,"[C!H0][Br,I]",*C +2456,Filter76_S_ester,CC(=S)O,CC(O)=S +2457,Filter77_alkyl_NO2,"[*!#7]~[#6]-,=CN(~O)(~O)",*~CCN(~O)~O +2458,Filter78_bicyclic_Imide,*~@C1C(=O)NC(=O)C(~@*)1,*~C1C(~*)C(=O)NC1=O +2459,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1 +2460,Filter80_Thioepoxide_aziridone,"[N,S]1[C,N,S][C,N,S]1",*1**1 +2461,Filter81_Thiocarbamate,"S!@C(=!@[O,S])!@[#7]",*=C(~N)~S +2462,Filter82_pyridinium,"[c,n]1[c,n][c,n][c,n][c,n]n(C)1",Cn1*:*:*:*:*1 +2463,Filter83_per_halo_chain,"[F,Cl,Br,I]C-,=;!@C([F,Cl,Br,I])-,=;!@C([F,Cl,Br,I])",*CC(*)C* +2464,Filter84_nitrogen_mustard,"[N,P,Se,S][C!H0]C[Br,Cl,I]",*CC* +2465,Filter85_keto_acrylonitrile,*C(=O)C(=!@[C!H0])C#N,*C(=O)C(=C)C#N +2466,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N +2467,Filter87_crowns,"[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[O,N]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@C",*C~C*C~C*C~C*C +2468,Filter88_ene_sulfone,[C!H0]=CS(=O)(=O)*,*S(=O)(=O)C=C +2469,Filter89_hydroxylamine,"[*!$(C=O)]!@N!@O[*,#1]",*~N~O* +2470,Filter90_N_double_bond_S,N=!@S,N=S +2471,Filter92_trityl,*(c1ccccc1)(c1ccccc1)(c1ccccc1),c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2472,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O +2473,Filter94_2_halo_pyridine,"c1nc(ccc1)[Br,I,Cl,F]",*c1ccccn1 +2474,Anhydride,C(=O)OC(=O),O=COC=O +2475,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1 +2476,Any carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2477,HOBT ester,C(=O)Onnn,nnnOC=O +2478,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-] +2479,Imine2,"[#6,#8,#16]-[CH1]=[NH1]",*C=N +2480,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N +2481,Cyanohydrin,N#CC[OH],N#CC[OH] +2482,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl +2483,P/S halide,"[P,S][F,Cl,Br,I]",** +2484,Quaternary,"[C+,Cl+,I+,P+,S+]",* +2485,Unacceptable atoms,[!#6;!#7;!#8;!#16;!#1;!#3;!#9;!#11;!#12;!#15;!#17;!#19;!#20;!#30;!#35],* +2486,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2487,b-Carbonyl quaternary nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2488,Benzylic quaternary nitrogen,cC[N+],cC[N+] +2489,Phosphorane,C=P,C=P +2490,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S +2491,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2492,Sulfonate,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2493,Heteroaryl sulfonate,"a-S(=O)(=O)-O[$([a&!#6]),$(c[a&!#6]),$(cc[a&!#6]),$(ccc[a&!#6]),$(cccc[a&!#6]),$(ccccc[a&!#6])]",*OS(*)(=O)=O +2494,Sulfate ester,"COS(=O)O[C,c]",*OS(=O)OC +2495,Polyacidic,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2496,Thiol,[SH],[SH] +2497,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1 +2498,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +2499,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2500,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2501,Allene,*=C=*,*=C=* +2502,Azide,"[$(*-[NX2-]-[NX2+]#[NX1]),$(*-[NX2]=[NX2+]=[NX1-]),$(N=N=N)]",* +2503,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O +2504,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2505,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH] +2506,Ester,[#6]-C(=O)O-[#6],COC(C)=O +2507,Imine 1,"[#6,#8,#16]-C(=[NH1])[#6,#8,#16]",*C(*)=N +2508,Imine 3,C=[NH],C=N +2509,Thioketone,CC(=S)C,CC(C)=S +2510,Thionoester,COC(=S)C,COC(C)=S +2511,Thioamide,CC(=S)N,CC(N)=S +2512,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC +2513,Long aliphatic chain,"[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]",******* +2514,Unbranched chain,"[$([A&D2]),$([A&D1])]!@[A&D2]!@[A&D2]!@[A&D2]!@[A&D2]!@[$([A&D2]),$([A&D1])]",*~*~*~*~*~* +2515,Dye 25,acC=&!@Cca,*cC=Cc* +2516,Isonitrile,[N+]#[C-],[C-]#[NH+] +2517,Thiocyanate,SC#N,N#CS +2518,Dye 16 (1),"c[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c +2519,Nitro aromatic 2+,"a-[$([NX3](=O)=O),$([NX3+](=O)[O-])].a-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",**.** +2520,Dye 29,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-caac-[$(N(C)C),$([NH]C),$([NH2])]",*c*:*c* +2521,Dye 1 (1),"c1cccc(C(=O)[C,c]([#7])=,:[C,c]([#7])C2(=O))c12",N*1=*(N)C(=O)c2ccccc2C1=O +2522,Dye 7,"N=C1[#6]:,=[#6]C(=[C,N])[#6]:,=[#6]1",*=C1C:CC(=N)C:C1 +2523,Dye 11,"*=,:[#6]C([#6]=,:*)[#6]=,:*",*=CC(C=*)C=* +2524,Dye 9,ac-*=&!@*-&!@C(=O)-&!@ca,*c*=*C(=O)c* +2525,Dye 32,"c1cccc2C(=O)C(C:,=*)C(=O)c12",*:CC1C(=O)c2ccccc2C1=O +2526,Dye 6,c12cccc(C(=O)C(ca)C(=O)3)c2c3ccc1,*cC1C(=O)c2cccc3cccc(c23)C1=O +2527,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1 +2528,Dye 2,OCccCO,OCccCO +2529,Dye 26,c1ccccc1-n2nnnc2[CH2]*,*[CH2]c1nnnn1-c1ccccc1 +2530,Perhalo_ketone,"O=CC(-[F,Cl,Br,I])([F,Cl,Br,I])-[F,Cl,Br,I]",*C(*)(*)C=O +2531,Beta halo carbonyl,"O=CCC[F,Cl,Br,I]",*CCC=O +2532,4-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[n]:[c,n]:[c,n]1",*c1*:*n*:*1 +2533,2-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[c,n]:[c,n]:[n]1",*c1*:*:*:*n1 +2534,Hetero_hetero,"*[N,S,O]-&!@[N,S,O][#6]",***C +2535,Disulfide,SS,SS +2536,Vinyl michael acceptor1,"[#6]-[CH1]=C-C(=O)[#6,#7,#8]",*C(=O)C=CC +2537,Vinyl michael acceptor2,"[CH2]=C-C(=O)[#6,#7,#8]",*C(=O)C=C +2538,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N +2539,Michael acceptor 6,"[#6,#7]-&!@[#6](=&!@[CH])-&!@C(=O)-&!@[C,N,O,S]",*C(=[CH])C(*)=O +2540,Alkynyl michael acceptor1,"[#6]-C#CC(=O)[#6,#7,#8]",*C(=O)C#CC +2541,Alkynyl michael acceptor2,"[CH1]#CC(=O)-[#6,#7,#8]",*C(=O)C#C +2542,Nitroalkane,"C[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*C +2543,Nitrate,"[#6]-O-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*OC +2544,Oxalyl,O=C-&!@C=O,O=CC=O +2545,Dipeptide,*-C(=O)-&!@[NH]-C-&!@C(=O)-&!@[NH]-*,*NC(=O)CNC(*)=O +2546,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-] +2547,Triphenylphosphine,a-P(-a)-a,*P(*)* +2548,Phosphoric acid,[OH]-P(=O)(-O)-*,*P(=O)(O)O +2549,Phosphoric ester,COP(=O)(-*)O,*P(O)(=O)OC +2550,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2551,Tri phosphoric esters,[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6],*P(=O)(OC)OC.*P(=O)(OC)OC.*P(=O)(OC)OC +2552,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O +2553,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12 +2554,Poly(azo(anthracene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1[c,n]c3:[c,n]:[c,n]:[c,n]:[c,n]:c3[c,n]2",*1:*:*c2*c3*:*:*:*c3*c2*:1 +2555,Poly(azo(phenanthrene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1:[c,n]:[c,n]:c3:[c,n]:[c,n]:[c,n]:[c,n]:c23",*1:*:*c2c(*:1)*:*c1*:*:*:*c12 +2556,Dye 31,a1aaac2ac3acac4aaac(c34)c12,*1:*:*c2c(*:1)*c1*c*c3*:*:*c2c31 +2557,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21 +2558,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O +2559,"Epoxide, aziridine, thioepoxide","C1[O,S,N]C1",*1CC1 +2560,Propiolactone,C1(=O)OCC1,O=C1CCO1 +2561,b-Lactam,N1CCC1=O,O=C1CCN1 +2562,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2563,Aromatic sulfonic ester,"[#6,#7]-S(=O)(=O)Oc",*S(=O)(=O)Oc +2564,Quinone,"[$([o,n]=c1ccc(=[o,n])cc1),$([O,N]=C1C=CC(=[O,N])C=C1),$([O,N]=C1[#6]:,=[#6]C(=[O,N])[#6]:,=[#6]1)]",* +2565,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2566,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2567,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2568,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1 +2569,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2570,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1 +2571,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2572,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2573,Acid_anhydrides,C(=O)OC(=O),O=COC=O +2574,Acid_halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2575,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1 +2576,Active_phosphate,"P(=S)([OH1,O$(O[#6])])([OH1,O$(O[#6])])[S,O]",*P(*)(*)=S +2577,Acyl_cyanide,C(=O)-C#N,N#CC=O +2578,Adjacent_ring_double_bonds,[*;R]=[*;R]=[*;R],*=*=* +2579,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F +2580,Alkyl_halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2581,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C +2582,Alpha_halo_carbonyl,"[C;!$(C[N])](=O)!@[C;h1,h2;H1,H2][F,Cl,Br,I]",*C~C=O +2583,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O +2584,Aminonitrile,NC#N,NC#N +2585,Any_carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2586,Aromatic_azides,"c[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*c +2587,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-] +2588,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2589,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1 +2590,B-carbonyl_quaternary_nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2591,Benzylic_quaternary_nitrogen,"cC[N+,NX4]",*Cc +2592,Beta-carbonyl_quaternary_nitrogen,"C(=O)C[N+,n+,NX4,nX4]",*CC=O +2593,Beta-fluoro-ethyl-on,"[C;H2$(CF),H1$(C(F)F)]!@[CH2][N,O]",*[CH2]~C +2594,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2595,Carbazides,"C(=O)[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*C=O +2596,CCl3-CHO_releasing,"C(Cl)(Cl)(Cl)C([O,S])[NX3]",*C(N)C(Cl)(Cl)Cl +2597,Conjugated_dithioether,SC(=[!r])S,*=C(S)S +2598,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1 +2599,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1 +2600,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1 +2601,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2602,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2603,Diacetylene,C#CC#C,C#CC#C +2604,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-] +2605,Diazonium_salt,[N+]#N,N#[NH+] +2606,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O +2607,Dinitrobenzene_1,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc1",*c1ccccc1* +2608,Dinitrobenzene_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])c1",*c1ccc(*)cc1 +2609,Dinitrobenzene_3,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1cccc(*)c1 +2610,Dithiocarbamate,NC(=S)S,NC(S)=S +2611,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1 +2612,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1 +2613,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS +2614,Enyne,C=!@CC#C,C#CC=C +2615,"Epoxides,_thioepoxides,_aziridines","C1[O,S,N]C1",*1CC1 +2616,Ester_of_HOBT,C(=O)Onnn,nnnOC=O +2617,Flavin,"c1cccc(NC(=NC(=[N,S,O])NC(=O)3)C3=N2)c12",*=C1NC(=O)C2=Nc3ccccc3NC2=N1 +2618,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2 +2619,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF +2620,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F +2621,Four_member_lactones,C1(=O)OCC1,O=C1CCO1 +2622,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN +2623,Geminal_dinitriles,N#CCC#N,N#CCC#N +2624,"Halo-pyridine, -diazoles and -triazoles","[Cl,Br,I]c1[c,n][c,n][c,n][c,n]n1",*c1*:*:*:*n1 +2625,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1 +2626,Imines_(not_ring),"[#6][CR0](=[NR0,OR0])[#6]",*=C(C)C +2627,Isocyanates_and_isothiocyanates,"N=C=[S,O]",*=C=N +2628,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S +2629,Michael_phenyl_ketone,c1ccccc1C(=O)C=!@CC(=O)!@*,*~C(=O)C=CC(=O)c1ccccc1 +2630,Nitrobenz-azadiazole_1,"c1ccc(n[o,s]n2)c2c1[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c1cccc2n*nc12 +2631,Nitrobenz-azadiazole_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc(n[o,s]n2)c2c1",*c1ccc2n*nc2c1 +2632,Nitrosamine,N-[N;X2](=O),NN=O +2633,Noname,"N1=C[S,NH1]C(=[C,N,P][C,N,O,P])C1(=O)",**=C1*C=NC1=O +2634,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-] +2635,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN +2636,Orthoester,C(O)(O)[OH],OC(O)[OH] +2637,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH] +2638,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1 +2639,P_or_S_halides,"[P,S][Cl,Br,F,I]",** +2640,P-aminoaryl_diazo,Nc1aaa(N!@=N)aa1,Nc1*:*:*(N~N):*:*1 +2641,PCP,PCP,PCP +2642,Paranitrophenyl_esters,"C(=O)Oc1ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1ccc(OC=O)cc1 +2643,Pentahalophenyl,"c1c([F,Cl])c([F,Cl])c([F,Cl])c([F,Cl])c1([F,Cl])",*c1cc(*)c(*)c(*)c1* +2644,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2645,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34 +2646,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1 +2647,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O +2648,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2649,Phosphorus_halide,"[S,P][F,Cl,Br,I]",** +2650,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2651,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc +2652,Polyines,CC#CC#CC,CC#CC#CC +2653,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1 +2654,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12 +2655,Polysulfide,*[SX2][SX2][SX2]*,*SSS* +2656,Sulphur_halide,"[#16][F,Cl,Br,I]",*S +2657,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34 +2658,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1 +2659,Reactive_carbonyls,"[C;!r](=[O,S])[S;!r]",*=CS +2660,Ring_triple_bond,"[C,c;R]#[C,c;R]",*#* +2661,S=N (not_ring),[S;R0]=[N;R0],N=S +2662,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O +2663,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2664,Sulphate_ester,"COS(=O)O[C,c]",*OS(=O)OC +2665,Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2666,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S +2667,Tetraazinane,C1NNC=NN1,C1NNC=NN1 +2668,Thioles_(not_aromatic),[!a][SX2;H1],*S +2669,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S +2670,Three_membered_heterocycle,"*1[O,S]*1",*1**1 +2671,Tri_pentavalent_S,"[#16v3,#16v5]",* +2672,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1 +2673,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1 +2674,Triphenylphosphines,P(c1aaaaa1)(c1aaaaa1)(c1aaaaa1),*1:*:*c(P(c2*:*:*:*:*2)c2*:*:*:*:*2)*:*:1 +2675,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1 +2676,Vinyl_halide,"[Cl,Br,I]C=[!O!R]",*C=* +2677,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O +2678,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O +2679,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1 +2680,Oxime,"[#6]C(=!@N[$(OC),$([OH])])[#6]",*N=C(C)C +2681,Hydrazone,[#6]C(=!@NNa)[#6],*NN=C(C)C +2682,Nitrosone_not_nitro,[$(N(~!@[#6])!@O);!$([N+]([O-])=O)],* +2683,Thiocarbonyl_group,C=S,C=S +2684,Enamine_like,C=[NH],C=N +2685,Analine,"c1ccccc1[NH2,NH3+]",*c1ccccc1 +2686,Acid_anhydrides_2,"[#6]C(=O)!@OC(=!@[N,O])[#6]",*=C(C)O~C(C)=O +2687,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F +2688,Triple_bond,[#6]C#[CH],CC#C +2689,Thiatetrazolidine,"[$(Sc1nnn[nH,n-]1),$(Sc1nn[nH,n-]n1)]",* +2690,Glycol,"[#6][O;R0][$(C([#6])[#6]),$([CH][#6]),$([CH2])][O;R0][#6]",CO*OC +2691,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O +2692,Formate_formide,"O=[CH][O,N][#6]",C*[CH]=O +2693,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1 +2694,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1 +2695,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1 +2696,Thiazolidinone,O=C1CSCN1,O=C1CSCN1 +2697,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1 +2698,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1 +2699,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1 +2700,Ethene,C=[CH2],C=C +2701,Cyclobutene,C1CC=C1,C1CC=C1 +2702,Poly_sub_atomatic,*!@c1c(!@*)c(!@*)c(!@*)c(!@*)c1,*~c1cc(~*)c(~*)c(~*)c1~* +2703,Isotopes,"[2#1,3#1,11C,11c,14C,14c,125I,32P,33P,35S]",* +2704,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C +2705,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-] +2706,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-] +2707,Sulphur atom (1),[SX2H1],[SH] +2708,Sulphur atom (2),"[$([SX2H0]);!$([S][#6X3,#7X2]);!$([S][CX4H0])]",* +2709,Sulphur atom (3),"[$([SX2H0][#6X3,#7X2]);!$([S](~[#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2710,Sulphur atom (4),[$([S][*D4H0]);$([SX2H0])],* +2711,Sulphur atom (5),"[$([SX2H0]([#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2712,Sulphur atom (6),[sX2r5],s +2713,Sulphur atom (7),[$([#16X3](=[OX1]));$([#16]);!$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2714,Sulphur atom (8),[$([#16X3](=[OX1]));$([#16]);$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2715,Aldehyde carbon atoms,[$([CX3H1](=O)[#6])],* +2716,Phosphor with double bonded sulphur,[$([PX4]);$([P]=[S])],* +2717,sp3 hybridized carbon atoms (1),[$([CX4]([#6X3])([#6X3])[#6X3]);!$([CH0])],* +2718,sp3 hybridized carbon atoms (2),"[$([CX4][N]);!$([CH0]);!$([C][N]([#6X3,#7X2])[#6X3,#7X2]);!$([C][N]=[#6X3]);!$([CX4][NX3][C]=[O])]",* +2719,sp3 hybridized carbon atoms (3),"[!$([CH0]);$([CX4]([#6X3])[#6X3]),$([CX4][#7]=[#6X3]),$([CX4]([#8])[#8]);!$([CX4]([#8])[#8][C]=[O])]",* +2720,sp3 hybridized carbon atoms (4),[$([CX4][S]);!$([CH0]);!$([C][S]=[O])],* +2721,sp3 hybridized carbon atoms (5),"[$([CX4][#6X3]~[#8]),$([CX4][#6X3](~[#7])~[#7]),$([CX4][#6X2]),$([CX4][CX3]=[CX3]-[#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3]);!$([CX4][#6X3](=[#8])-[#8]);!$([CX4][CX3]([CX3])=[CX3]-[#6X3])]",* +2722,sp3 hybridized carbon atoms (6),[$([CX4][O]);!$([CH0]);!$([C][O][C]=[O]);!$([CX4]1[O][C]1)],* +2723,sp3 hybridized carbon atoms (7),[$([CX4][#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3])],* +2724,sp3 hybridized carbon atoms (8),"[$([CX4][#7](~[#6X3,#7X2])~[#6X3,#7X2]);!$([CH0])]",* +2725,sp3 hybridized carbon atoms (9),[$([CX4][S](=[O])=[O]);!$([CH0])],* +2726,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C +2727,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C +2728,sp3 hybridized carbon atoms (12),[$([CX4][NX3H1][C]=[O]);!$([CH0])],* +2729,sp2 hybridized carbon atoms (1),"[$([CX3H2]);$([C]=[#6X3,#7X2]-[#6X3,#7X2])]",* +2730,sp2 hybridized carbon atoms (2),"[$([CX3H1]);$([C]=[#6X3,#7X2]-[#6X3,#7X2]);!$([C](-[#6X3,#7X2])=[#6X3,#7X2]-[#6X3,#7X2])]",* +2731,sp2 hybridized carbon atoms (3),[$([cH1]);$([c](:[#7]):[#7])],* +2732,sp2 hybridized carbon atoms (4),"[$([ch1]);!$([ch1]1:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]:[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]1);$([ch1]1:[c](-[NX3]):[c]:[c]:[c]:[c]1),$([c]1:[c]:[c]:[c](-[NX3]):[c]:[c]1)]",* +2733,sp2 hybridized carbon atoms (5),"[$([CX3]);$([CX3]=[CX3]);!$([CH0]);!$([CX3](-[#6X3,#7X2])=[CX3]);!$([CX3]=[CX3]-[#6X3,#7X2])]",* +2734,sp2 hybridized carbon atoms (6),[$([cH1]);$([c]:[#16])],* +2735,sp2 hybridized carbon atoms (7),"[$([ch1]);$([c]1:[c]:[c]:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]1),$([c]1:[c]:[c]:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1)]",* +2736,sp2 hybridized carbon atoms (8),"[$([ch1]);!$([c]1:[c]:[c]:[c](-[O]-[C]=[O]):[c]:[c]1);$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1),$([c]1:[c]:[c]:[c](-[O,SX2]):[c]:[c]1)]",* +2737,sp2 hybridized carbon atoms (9),[$([cH1]);$([c]1:[c]:[#16]:[c]:[c]1)],* +2738,sp2 hybridized carbon atoms (10),"[$([ch1]);$([ch1]1:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]1:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]:[c]-[O,SX2]);!$([ch1]:[c]-[O]-[C]=[O])]",* +2739,sp2 hybridized carbon atoms (11),"[$([CX3H1,cX3H1]);!$([ch1]1:[c]:[c]:[#7]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]1);!$([ch1]:[#7])]",* +2740,sp2 hybridized carbon atoms (12),"[$([ch1]1:[c]:[c]:[#7]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]1),$([ch1]:[#7])]",* +2741,Nitrogen atoms (1),"[$([NX3H0]);!$([NX3][#6X3,#7X2])]",* +2742,Nitrogen atoms (2),"[$([NX3]);$([H1,H2])]",* +2743,Nitrogen atoms (3),[$([N]([#6X3]1)[#6X3]=[#6X3][#6X4][#6X3]=1)],* +2744,Nitrogen atoms (4),"[$([NX3H0]);$([NX3][#6X3,#7X2]);!$([NX3]([#6X3,#7X2])[#6X3,#7X2])]",* +2745,Nitrogen atoms (5),"[$([nr6]),$([NX2]=[C])]",* +2746,Nitrogen atoms (6),"[$([N]);$([NX3H0]([#6X3,#7X2])[#6X3,#7X2]),$([NX2H1][C]=[O])]",* +2747,Nitrogen atoms (7),[nr5H0],n +2748,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21 +2749,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C +2750,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1 +2751,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1 +2752,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1 +2753,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1 +2754,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1 +2755,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1 +2756,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1 +2757,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1 +2758,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1 +2759,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1 +2760,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1 +2761,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2 +2762,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC +2763,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1 +2764,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1 +2765,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1 +2766,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1 +2767,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1 +2768,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1 +2769,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1 +2770,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1 +2771,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1 +2772,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12 +2773,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1 +2774,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1 +2775,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1 +2776,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1 +2777,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1 +2778,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1 +2779,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2 +2780,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2 +2781,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1 +2782,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2 +2783,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +2784,4-chlorobenzene,Clc1ccc([*:1])cc1,Clc1ccc([*:1])cc1 +2785,4-nitrobenzene,[O-][N+](=O)c1cc([*:1])c([*:1])cc1,O=[N+]([O-])c1ccc([*:1])c([*:1])c1 diff --git a/Experiments/BBBP/BBBP.csv b/Experiments/BBBP/BBBP.csv new file mode 100644 index 0000000000000000000000000000000000000000..7645031a19ee4e07244f83b4ac7ca50f8cc06209 --- /dev/null +++ b/Experiments/BBBP/BBBP.csv @@ -0,0 +1,2051 @@ +num,name,p_np,smiles +1,Propanolol,1,[Cl].CC(C)NCC(O)COc1cccc2ccccc12 +2,Terbutylchlorambucil,1,C(=O)(OC(C)(C)C)CCCc1ccc(cc1)N(CCCl)CCCl +3,40730,1,c12c3c(N4CCN(C)CC4)c(F)cc1c(c(C(O)=O)cn2C(C)CO3)=O +4,24,1,C1CCN(CC1)Cc1cccc(c1)OCCCNC(=O)C +5,cloxacillin,1,Cc1onc(c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C(O)=O +6,cefoperazone,1,CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(O)=O)CSc4nnnn4C)c5ccc(O)cc5)C(=O)C1=O +7,rolitetracycline,1,CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)c4c(O)cccc4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(/O)NCN5CCCC5)C1=O +8,ondansetron,1,Cn1c2CCC(Cn3ccnc3C)C(=O)c2c4ccccc14 +9,diltiazem,1,COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O +10,Amiloride,1,NC(N)=NC(=O)c1nc(Cl)c(N)nc1N +11,M2L-663581,0,OCC(C)(O)c1onc(c2ncn3c2CN(C)C(c4c3cccc4Cl)=O)n1 +12,alovudine,1,CC1=CN([C@H]2C[C@H](F)[C@@H](CO)O2)C(=O)NC1=O +13,18,1,C(Cl)Cl +14,24959,1,C1N(C(CC2CCCCC12)C(NC(C)(C)C)=O)CC(C(Cc1ccccc1)NC(C(NC(c1nc2c(cccc2)cc1)=O)CC(N)=O)=O)O +15,methadone,1,CCC(=O)C(CC(C)N(C)C)(c1ccccc1)c2ccccc2 +16,alfentanil,1,CCN1N=NN(CCN2CCC(CC2)(COC)N(C(=O)CC)c3ccccc3)C1=O +17,BRL53080,1,CN(C)C(=O)C(CCN1CCC(O)(CC1)c1ccc(Cl)cc1)(c1ccccc1)c1ccccc1 +18,hyoscyamine,1,CN1C2CCC1CC(C2)OC(=O)[C@H](CO)c3ccccc3 +19,glyburide,1,COc1ccc(Cl)cc1C(=O)NCCc2ccc(cc2)[S](=O)(=O)NC(=O)NC3CCCCC3 +20,lamotrigine,1,Nc1nnc(c(N)n1)c2cccc(Cl)c2Cl +21,2-Methylpentane,1,CCCC(C)C +22,Dexamfetamine,1,C[C@H](N)Cc1ccccc1 +23,SKF-93619,0,c1cc2c(cc(CC3=CNC(=NC3=O)NCCSCc3oc(cc3)CN(C)C)cc2)cc1 +24,nadolol,1,CC(C)(C)NCC(O)COc1cccc2C[C@@H](O)[C@@H](O)Cc12 +25,sufentanil,1,CCC(=O)N(c1ccccc1)C2(CCN(CCc3sccc3)CC2)COC +26,12,0,CCNC(=NC#N)NCCSCc1c(cccn1)Br +27,zolpidem,1,CN(C)C(=O)Cc1n2cc(C)ccc2nc1c3ccc(C)cc3 +28,clozapine,1,CN1CCN(CC1)C2=C3C=CC=CC3=Nc4ccc(Cl)cc4N2 +29,Org12692,1,FC(F)(F)c1c(Cl)nc(N2CCNCC2)cc1 +30,piperacillin,1,O.CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(O)=O)c4ccccc4)C(=O)C1=O +31,Pentobarbital,1,CCCC(C)C1(CC)C(=O)NC(=O)NC1=O +32,Levofloxacin,1,C[C@H]1COc2c(N3CCN(C)CC3)c(F)cc4C(=O)C(=CN1c24)C(O)=O +33,compound 40,1,c1ccc(C(NCCCOc2cc(CN3CCCCC3)ccc2)=O)cc1 +34,RO19-4603,1,CC(C)(C)OC(=O)C1=C2CN(C(=O)C3=C(N2C=N1)C=CS3)C +35,fentanyl,1,CCC(=O)N(C1CCN(CC1)CCc2ccccc2)c3ccccc3 +36,etomidate,1,CCOC(=O)c1cncn1C(C)c2ccccc2 +37,11a,0,CN(C)c1cc(C2=NC(N)=NN2)ccn1 +38,prochlorperazine,1,CN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 +39,2-(3'-Iodo-4'-aminophenyl)-6-hydroxybenzothiazole,1,IC1=C(N([H])[H])C=CC(C2=NC3=CC=C(O[H])C=C3S2)=C1 +40,compound 34,0,O=C(C)Nc1cc(c2csc(N=C(N)N)n2)ccc1 +41,granisetron,1,CN1[C@H]2CCC[C@@H]1CC(C2)NC(=O)c3nn(C)c4ccccc34 +42,thiamphenicol,1,C[S](=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl +43,16,1,c1ccc(cc1)c1csc(n1)N=C(N)N +44,mexiletine,1,CC(N)COc1c(C)cccc1C +45,dextropropoxyphene,1,CCC(=O)O[C@@](Cc1ccccc1)([C@H](C)CN(C)C)c2ccccc2 +46,Nor-1-chlorpromazine,1,ClC1=CC=C(C2=C1)SC3=C(N2CCCNC)C=CC=C3 +47,compound 37,1,CN(C)Cc1ccc(c2cccc(NC3C([N+]([O-])=O)=CC=N3)c2)o1 +48,cefamandole,1,Cn1nnnc1SCC2=C(N3[C@H](SC2)[C@H](NC(=O)[C@H](O)c4ccccc4)C3=O)C(O)=O +49,Y-G 15,1,n(ccc1)c(c1)CCN(C)C +50,Org13011,1,O=C1N(CCC1)CCCCN2CCN(CC2)c3cc(C(F)(F)F)ccn3 +51,Quinidine,1,COc1ccc2nccc([C@H](O)[C@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1 +52,38480,1,c1(ccccc1)CC +53,17,1,c1ccc(cc1N)c1csc(n1)N=C(N)N +54,vinblastine,1,CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C)[C@H]7[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@H]89)C(=O)OC)C1 +55,Bacitracin,1,c1(c(cc(NC(CCC)=O)cc1)C(C)=O)OCC(CNC(C)C)O +56,Nor-2-chlorpromazine,1,ClC1=CC=C(SC(C=CC=C2)=C2N3CCCN)C3=C1 +57,compound 36,1,CN(C)Cc1ccc(CSCCNC2=C([N+]([O-])=O)C(Cc3ccccc3)=CN2)o1 +58,19,0,CNC(=NC#N)Nc1cccc(c1)c1csc(n1)N=C(N)N +59,Y-G 14,1,n(ccc1)c(c1)CCNC +60,15,1,O=N([O-])C1=C(CN=C1NCCSCc2ncccc2)Cc3ccccc3 +61,sertraline,1,[Cl-].CN[C@H]1CC[C@@H](c2ccc(Cl)c(Cl)c2)c3ccccc13.[H+] +62,22767,1,c1(nc(NC(N)=[NH2])sc1)CSCCNC(=[NH]C#N)NC +64,vincristine,1,CC[C@]1(O)C[C@H]2CN(CCc3c([nH]c4ccccc34)[C@@](C2)(C(=O)OC)c5cc6c(cc5OC)N(C=O)[C@H]7[C@](O)([C@H](OC(C)=O)[C@]8(CC)C=CCN9CC[C@]67[C@H]89)C(=O)OC)C1 +65,SB-222200,1,CCC(NC(=O)c1c(c(nc2c1cccc2)c1ccccc1)C)c1ccccc1 +66,SB-656104-A,1,ClC1=CC=CC(OC2CCN(CCC3CCCN3S(C4=CC(N([H])C=C5)=C5C=C4)(=O)=O)CC2)=C1 +67,compound 38,1,CN(C)Cc1ccnc(c2cccc(NC3C([N+]([O-])=O)=CC=N3)c2)c1 +68,maprotiline,1,CNCCCC12CCC(c3ccccc13)c4ccccc24 +69,compound 43,1,N1(Cc2cc(OCCCNc3nccs3)ccc2)CCCCC1 +70,MIL-663581,0,OC(C)(C)c1onc(c2ncn3c2CN(C)C(c4c3cccc4Cl)=O)n1 +71,cefotaxime,1,[Na+].CO\N=C(C(=O)N[C@@H]1[C@@H]2SCC(=C(N2C1=O)C([O-])=O)COC(C)=O)\c3csc(N)n3 +72,carbamazepine-10,1,C1=CC=C2C(=C1)C3C(O3)C4=CC=CC=C4N2C(=O)N +73,Cyclohexane,1,C1CCCCC1 +74,2,1,Cc1csc(n1)N=C(N)N +75,SKF89124,1,CCCN(CCc1c2c(c(cc1)O)NC(=O)C2)CCC +76,Org5222,1,Clc1cc2c(Oc3ccccc3C3CN(CC32)C)cc1 +77,compound 35,0,CN(C)Cc1oc(CSCCNC2C([N+]([O-])=O)=CC=N2)cc1 +78,cefuroxime,1,CO/N=C(C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(O)=O)COC(N)=O)/c3occc3 +79,compound 45,1,N1(Cc2cc(OCCCNc3oc4ccccc4n3)ccc2)CCCCC1 +80,Org4428,1,OC12c3c(Oc4c(C)cccc4C2CN(CC1)C)cccc3 +81,compound 32,1,[O-][N+](C1=CC=NC1NCCSCc2ccccn2)=O +82,Bretyliumtosilate,1,c12c(nc([nH]1)NC(OC)=O)cc(SCCC)cc2 +83,Y-G 20,0,c1cccn2c1nc(c2)CCN +84,ornidazole,1,Cc1ncc(n1CC(O)CCl)[N+]([O-])=O +85,SKF101468,1,CCCN(CCc1c2c(ccc1)NC(=O)C2)CCC +86,Org30526,1,Clc1cc2c(Oc3ccccc3C3CNCC32)cc1 +87,36,1,CN(CCC=C1c2ccccc2CCc2ccccc12)C +88,ceftriaxone,1,CO/N=C(C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C(O)=O)CSC3=NC(=O)C(=O)NN3C)/c4csc(N)n4 +89,compound 42,1,N1(Cc2cccc(OCCCNc3ccccn3)c2)CCCCC1 +90,Org32104,1,OC12c3c(Oc4c(C)cccc4C2CNCC1)cccc3 +91,compound 31,1,[O-][N+](C1=CC=NC1NCCSCc2ncccc2Br)=O +92,SB204457,1,c12c3c(C(NC(C)=O)CCc2cc(c(c1OC)OC)OC)cc(=O)c(cc3)OC +93,compound 41,1,C1CCN(CC1)Cc1cc(OCCCO)ccc1 +94,clomethiazole,1,Cc1ncsc1CCCl +95,celiprolol,1,CCN(CC)C(=O)Nc1ccc(OCC(O)CNC(C)(C)C)c(c1)C(C)=O +96,"""1,1,1-Trifluro-2-chloroethane""",1,ClCC(F)(F)F +97,33,1,CN1C(=O)c2c(cccc2Cl)n2cnc(c2C1)c1noc(n1)C(C)C +98,cefoxitin,1,CO[C@]1(NC(=O)Cc2sccc2)[C@H]3SCC(=C(N3C1=O)C(O)=O)COC(N)=O +99,Org34167,1,NC(CC=C)c1ccccc1c2noc3c2cccc3 +100,9-OH Risperidone,1,OC1C(N2CCC1)=NC(C)=C(CCN3CCC(CC3)c4c5ccc(F)cc5on4)C2=O +101,acetaminophen,1,CC(=O)Nc1ccc(O)cc1 +102,acetylsalicylate,0,CC(=O)Oc1ccccc1C(O)=O +103,allopurinol,0,O=C1N=CN=C2NNC=C12 +104,Alprostadil,0,CCCCC[C@H](O)/C=C/[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O +105,aminophylline,0,CN1C(=O)N(C)c2nc[nH]c2C1=O.CN3C(=O)N(C)c4nc[nH]c4C3=O.NCCN +106,Amiodarone,0,CCCCc1oc2ccccc2c1C(=O)c3cc(I)c(OCCN(CC)CC)c(I)c3 +107,amoxicillin,0,O.O.O.CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(O)=O +108,ampicillin,0,CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccccc3)C(=O)N2[C@H]1C(O)=O +109,androsan,0,C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C +110,oxaflumazine,1,OC(=O)CCC(O)=O.FC(F)(F)c1ccc2Sc3ccccc3N(CCCN4CCN(CCC5OCCCO5)CC4)c2c1 +111,oxazepam,1,OC1N=C(c2ccccc2)c3cc(Cl)ccc3NC1=O +112,oxiperomide,1,O=C1Nc2ccccc2N1C3CCN(CCOc4ccccc4)CC3 +113,oxycodone,1,COc1ccc2C[C@H]3N(C)CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O +114,oxymorphone,1,CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@]2(O)CCC4=O)c35 +115,pecazine,1,CN1CCCC(C1)CN2c3ccccc3Sc4ccccc24 +116,pemoline,1,NC1=NC(=O)C(O1)c2ccccc2 +117,pentazocine,1,C[C@@H]1[C@H]2Cc3ccc(O)cc3[C@]1(C)CCN2CC=C(C)C +118,Ethionamide,1,CCc1cc(ccn1)C(N)=S +119,Etoposide,0,COc1cc(cc(OC)c1O)[C@H]2[C@@H]3C(COC3=O)[C@H](O[C@@H]4O[C@@H]5CO[C@@H](C)O[C@H]5[C@H](O)[C@H]4O)c6cc7OCOc7cc26 +120,Famotidine,1,NC(N)=Nc1scc(CSCCC(N)=N[S](N)(=O)=O)n1 +121,Fluconazole,1,OC(Cn1cncn1)(Cn2cncn2)c3ccc(F)cc3F +122,Foscarnetsodium,1,[Na+].[Na+].[Na+].[O-]C(=O)[P]([O-])([O-])=O +123,Gabapentin,1,NCC1(CCCCC1)CC(O)=O +124,Nafcillin,0,[Na+].CCOc1ccc2ccccc2c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C([O-])=O +125,Nalidixicacid,0,CCN1C=C(C(O)=O)C(=O)c2ccc(C)nc12 +126,Nelfinavir,0,Cc1c(O)cccc1C(=O)N[C@@H](CSc2ccccc2)[C@H](O)CN3C[C@H]4CCCC[C@H]4C[C@H]3C(=O)NC(C)(C)C +127,Astemizole,0,COc1ccc(CCN2CCC(CC2)Nc3nc4ccccc4n3Cc5ccc(F)cc5)cc1 +128,atropine,0,CN1C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3 +129,Auxeomycin,0,[Cl-].CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)c4c(O)ccc(Cl)c4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(N)/O)C1=O.[H+] +130,Betamethasone,0,C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO +131,carbenicillin,0,CC1(C)S[C@@H]2[C@H](NC(=O)C(C(O)=O)c3ccccc3)C(=O)N2[C@H]1C(O)=O +132,carbidopa,0,C[C@@](Cc1ccc(O)c(O)c1)(NN)C(O)=O +133,carteolol,0,CC(C)(C)NCC(O)COc1cccc2NC(=O)CCc12 +134,Cefazolin,0,[Na+].Cc1sc(SCC2=C(N3[C@H](SC2)[C@H](NC(=O)Cn4cnnn4)C3=O)C([O-])=O)nn1 +135,cephapirin,0,CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSc3ccncc3)C2=O)C(O)=O +136,chlorambucil,0,OC(=O)CCCc1ccc(cc1)N(CCCl)CCCl +137,pergolide,1,CCCN1C[C@H](CSC)C[C@H]2[C@H]1Cc3c[nH]c4cccc2c34 +138,perlapine,1,CN1CCN(CC1)C2=Nc3ccccc3Cc4ccccc24 +139,perphenazine-HCl,1,OCCN1CCN(CCCN2c3ccccc3Sc4ccc(Cl)cc24)CC1 +140,pethidine,1,CCOC(=O)C1(CCN(C)CC1)c2ccccc2 +141,phencyclidine,1,C1CCN(CC1)C2(CCCCC2)c3ccccc3 +142,phenelzine sulfate,1,NNCCc1ccccc1.O[S](O)(=O)=O +143,phenobarbital,1,CCC1(C(=O)NC(=O)NC1=O)c2ccccc2 +144,phenprobamate,1,NC(=O)OCCCc1ccccc1 +145,physostigmine,1,CNC(=O)Oc1ccc2N(C)[C@H]3N(C)CC[C@@]3(C)c2c1 +146,Norepinephrine,0,NCC(O)c1ccc(O)c(O)c1 +147,Omeprazole,0,COc1ccc2nc([nH]c2c1)[S](=O)Cc3ncc(C)c(OC)c3C +148,Oxacillin,0,Cc1onc(c2ccccc2)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C(O)=O +149,Pentostatin,1,OC[C@H]1O[C@H](C[C@@H]1O)n2cnc3[C@H](O)CN=CNc23 +150,Phenoxymethylpenicillin,0,CC1(C)S[C@@H]2[C@H](NC(=O)COc3ccccc3)C(=O)N2[C@H]1C([O-])=O +151,chloramphenicol,0,OCC(NC(=O)C(Cl)Cl)C(O)c1ccc(cc1)[N+]([O-])=O +152,chlorothiazide,0,N[S](=O)(=O)c1cc2c(NC=N[S]2(=O)=O)cc1Cl +153,chlorpropamide,0,CCCNC(=O)N[S](=O)(=O)c1ccc(Cl)cc1 +154,Chlortetracycline,0,CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)c4c(O)ccc(Cl)c4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(N)/O)C1=O +155,chlorthalidone,0,N[S](=O)(=O)c1cc(ccc1Cl)C2(O)NC(=O)c3ccccc23 +156,clofibrate,0,CCOC(=O)C(C)(C)Oc1ccc(Cl)cc1 +157,clofibric acid,0,CC(C)(Oc1ccc(Cl)cc1)C(O)=O +158,clotrimazole,0,Clc1ccccc1C(n2ccnc2)(c3ccccc3)c4ccccc4 +159,corticosterone,0,C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2C(=O)CO +160,Cortisone,0,C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)CC(=O)[C@H]23 +161,piflutixol,1,OCC[C@@H]1CCN(CC\C=C2/c3ccc(F)cc3Sc4ccc(cc24)C(F)(F)F)CC1 +162,pimozide,1,Fc1ccc(cc1)C(CCCN2CCC(CC2)N3C(=O)Nc4ccccc34)c5ccc(F)cc5 +163,pinoxepin,1,OCCN1CCN(CC\C=C/2c3ccccc3COc4ccc(Cl)cc24)CC1 +164,pipamperone,1,NC(=O)C1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)N3CCCCC3 +165,prazepam,1,Clc1ccc2N(CC3CC3)C(=O)CN=C(c4ccccc4)c2c1 +166,pregnanolone,1,CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C +167,primidone,1,CCC1(C(=O)NCNC1=O)c2ccccc2 +168,procaine,1,CCN(CC)CCOC(=O)c1ccc(N)cc1 +169,procyclidine,1,OC(CCN1CCCC1)(C2CCCCC2)c3ccccc3 +170,promazine,1,CN(C)CCCN1c2ccccc2Sc3ccccc13 +171,Pindolol,1,CC(C)NCC(O)COc1cccc2[nH]ccc12 +172,Plicamycin,1,CO[C@@H]([C@@H]1Cc2cc3cc(O[C@H]4C[C@@H](O[C@H]5C[C@@H](O)[C@H](O)[C@@H](C)O5)[C@H](O)[C@@H](C)O4)c(C)c(O)c3c(O)c2C(=O)[C@H]1O[C@H]6C[C@@H](O[C@H]7C[C@@H](O[C@H]8C[C@](C)(O)[C@H](O)[C@@H](C)O8)[C@H](O)[C@@H](C)O7)[C@H](O)[C@@H](C)O6)C(=O)[C@@H](O)[C@@H](C)O +173,Pravastatin,0,CC[C@H](C)C(=O)O[C@H]1C[C@H](O)C=C2C=C[C@H](C)[C@H](CC[C@@H](O)C[C@@H](O)CC(O)=O)[C@@H]12 +174,Praziquantel,1,O=C1CN(CC2N1CCc3ccccc23)C(=O)C4CCCCC4 +175,Trimethoprim,1,COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC +176,Trimetrexate,0,COc1cc(NCc2ccc3nc(N)nc(N)c3c2C)cc(OC)c1OC +177,Trometamol,0,NC(CO)(CO)CO +178,Trovafloxacin,1,NC1[C@H]2CN(C[C@@H]12)c3nc4N(C=C(C(O)=O)C(=O)c4cc3F)c5ccc(F)cc5F +179,Urea,1,NC(N)=O +180,coumarin,0,O=C1Oc2ccccc2C=C1 +181,dapsone,0,Nc1ccc(cc1)[S](=O)(=O)c2ccc(N)cc2 +182,Dehydrocholic acid,0,C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@H]3[C@H](CC(=O)[C@]12C)[C@@]4(C)CCC(=O)C[C@H]4CC3=O +183,dicumarol,0,OC1=C(CC2=C(O)Oc3ccccc3C2=O)C(=O)c4ccccc4O1 +184,dicyclomine,0,CCN(CC)CCOC(=O)C1(CCCCC1)C2CCCCC2 +185,Diethylstilbestrol,0,CC\C(c1ccc(O)cc1)=C(\CC)c2ccc(O)cc2 +186,Digitoxin,0,C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]2[C@@H](O)C[C@@H](O[C@@H]2C)O[C@H]3[C@@H](O)C[C@@H](O[C@@H]3C)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5CC[C@]7(C)[C@@H](CC[C@]67O)C8=CC(=O)OC8)C4 +187,Digoxin,0,C[C@H]1O[C@H](C[C@H](O)[C@@H]1O)O[C@H]2[C@@H](O)C[C@@H](O[C@@H]2C)O[C@H]3[C@@H](O)C[C@@H](O[C@@H]3C)O[C@H]4CC[C@@]5(C)[C@H](CC[C@@H]6[C@@H]5C[C@@H](O)[C@]7(C)[C@H](CC[C@]67O)C8=CC(=O)OC8)C4 +188,Domperidone,0,Clc1ccc2N(C3CCN(CCCN4C(=O)Nc5ccccc45)CC3)C(=O)Nc2c1 +189,promethazine-HCl,1,CC(CN1c2ccccc2Sc3ccccc13)N(C)C +190,propiomazine,1,CCC(=O)c1ccc2Sc3ccccc3N(CC(C)N(C)C)c2c1 +191,propofol,1,CC(C)c1cccc(C(C)C)c1O +192,protriptyline,1,CNCCCC1c2ccccc2C=Cc3ccccc13 +193,pyridazinone,1,O=C1C=CNN=C1 +194,quazepam,1,Fc1ccccc1C2=NCC(=S)N(CC(F)(F)F)c3ccc(Cl)cc23 +195,rescinnamine,1,CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)\C=C\c6cc(OC)c(OC)c(OC)c6 +196,reserpine,1,CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5cc(OC)ccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 +197,secobarbital,1,CCCC(C)C1(CC=C)C(=O)NC(=O)NC1=O +198,spiclomazine,1,[H+].[Cl-].Clc1ccc2Sc3ccccc3N(CCCN4CCC5(CC4)NC(=O)CS5)c2c1 +199,Atovaquone,0,OC1=C(C2CCC(CC2)c3ccc(Cl)cc3)C(=O)C(=O)c4ccccc14 +200,Azelaicacid,0,OC(=O)CCCCCCCC(O)=O +201,Azithromycin,0,CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)C(C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)CN(C)[C@H](C)[C@@H](O)[C@]1(C)O +202,Bacitracin,0,CCC(C)C(N)C1=NC(CS1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCCCC[C@@H]2NC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@H](Cc3[nH]cnc3)NC(=O)[C@@H](Cc4ccccc4)NC(=O)[C@@H](NC(=O)[C@@H](CCCN)NC2=O)[C@@H](C)CC +203,Bethanechol,0,[Cl-].CC(C[N+](C)(C)C)OC(N)=O +204,Bretyliumtosilate,0,CC[N+](C)(C)Cc1ccccc1Br.Cc2ccc(cc2)[S]([O-])(=O)=O +205,Bromocriptine,0,CC(C)C[C@@H]1N2C(=O)[C@](NC(=O)[C@H]3CN(C)[C@@H]4Cc5c(Br)[nH]c6cccc(C4=C3)c56)(O[C@@]2(O)[C@@H]7CCCN7C1=O)C(C)C +206,Buprenorphine,1,c12[C@]34[C@@]56[C@H]([N@@](CC7CC7)CC4)Cc2ccc(c1O[C@H]3[C@](OC)([C@H](C5)[C@](C(C)(C)C)(C)O)CC6)O +207,dopamine,0,NCCc1ccc(O)c(O)c1 +208,doxorubicin,0,COc1cccc2C(=O)c3c(O)c4C[C@](O)(C[C@H](O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5)c4c(O)c3C(=O)c12)C(=O)CO +209,doxycycline,0,O.C[C@@H]1[C@H]2[C@H](O)[C@H]3[C@H](N(C)C)C(=O)C(=C(N)/O)/C(=O)[C@@]3(O)C(=O)C2=C(O)c4c(O)cccc14 +210,Dyclonine,0,[Cl].CCCCOc1ccc(cc1)C(=O)CCN2CCCCC2 +211,Econazole,0,Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)cc1 +212,enkephalin,0,CC(C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(N)=O +213,Ephedrine,0,CN[C@@H](C)[C@H](O)c1ccccc1 +214,epinephrine,0,CNC[C@H](O)c1ccc(O)c(O)c1 +215,erythromycin,0,CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O +216,estradiol,0,C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@H]2O +217,tacrine,1,Nc1c2CCCCc2nc3ccccc13 +218,temazepam,1,CN1C(=O)C(O)N=C(c2ccccc2)c3cc(Cl)ccc13 +219,tetrabenzine,1,COc1cc2CCN3CC(CC(C)C)C(=O)CC3c2cc1OC +220,thc,1,CCCCCc1cc(O)c2[C@@H]3C=C(C)CC[C@H]3C(C)(C)Oc2c1 +221,thebaine,1,COC1=CC=C2[C@H]3Cc4ccc(OC)c5O[C@@H]1[C@]2(CCN3C)c45 +222,thiethylperazine,1,CCSc1ccc2Sc3ccccc3N(CCCN4CCN(C)CC4)c2c1 +223,thioridazine,1,CSc1ccc2Sc3ccccc3N(CCC4CCCCN4C)c2c1 +224,thiothixene,1,CN1CCN(CC/C=C/2c3ccccc3Sc4ccc(cc24)[S](=O)(=O)N(C)C)CC1 +225,tranylcypromine,1,[Cl-].N[C@@H]1C[C@H]1c2ccccc2.[H+] +226,trazodone,1,Clc1cccc(c1)N2CCN(CCCN3N=C4C=CC=CN4C3=O)CC2 +227,Busulfan,1,C[S](=O)(=O)OCCCCO[S](C)(=O)=O +228,Cefradine,0,CC1=C(N2[C@H](SC1)[C@H](NC(=O)[C@H](N)C3=CCC=CC3)C2=O)C(O)=O +229,Chloroquine,1,CCN(CC)CCCC(C)Nc1ccnc2cc(Cl)ccc12 +230,Cisapride,1,O.COC1CN(CCCOc2ccc(F)cc2)CCC1NC(=O)c3cc(Cl)c(N)cc3OC +231,Cladribine,1,Nc1nc(Cl)nc2n(cnc12)[C@H]3C[C@H](O)[C@@H](CO)O3 +232,Clidiniumbromide,0,[Br-].C[N+]12CCC(CC1)C(C2)OC(=O)C(O)(c3ccccc3)c4ccccc4 +233,estrone,0,C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CCC2=O +234,Ethacrynic acid,0,CCC(=C)C(=O)c1ccc(OCC(O)=O)c(Cl)c1Cl +235,ethinylestradiol,0,C[C@]12CC[C@H]3[C@@H](CCc4cc(O)ccc34)[C@@H]1CC[C@@]2(O)C#C +236,fenoterol,0,CC(Cc1ccc(O)cc1)NCC(O)c2cc(O)cc(O)c2 +237,floxuridine,0,OC[C@H]1O[C@H](C[C@@H]1O)N2C=C(F)C(=O)NC2=O +238,Flucloxacillin,0,Cc1onc(c1C(=O)N[C@H]2[C@H]3SC(C)(C)[C@@H](N3C2=O)C(O)=O)c4c(F)cccc4Cl +239,fluorouracil,0,FC1=CNC(=O)NC1=O +240,furosemide,0,N[S](=O)(=O)c1cc(C(O)=O)c(NCc2occc2)cc1Cl +241,ganciclovir,0,NC1=NC(=O)c2ncn(COC(CO)CO)c2N1 +242,glycopyrrolate,0,[Br-].C[N+]1(C)CCC(C1)OC(=O)C(O)(C2CCCC2)c3ccccc3 +243,trifluperidol,1,OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3cccc(c3)C(F)(F)F +244,triflupromazine,1,CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(F)(F)F +245,trifluroperazine,1,CN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 +246,trihexyphenidyl,1,OC(CCN1CCCCC1)(C2CCCCC2)c3ccccc3 +247,trimetozine,1,COc1cc(cc(OC)c1OC)C(=O)N2CCOCC2 +248,trimipramine,1,CC(CN(C)C)CN1c2ccccc2CCc3ccccc13 +249,tybamate,1,CCCCNC(=O)OCC(C)(CCC)COC(N)=O +250,uridine,1,OCC1OC(C(O)C1O)N2C=CC(=O)NC2=O +251,valproicacid,1,CCCC(CCC)C(O)=O +252,zimelidine,1,CN(C)C/C=C(/c1ccc(Br)cc1)c2cccnc2 +253,Clofazimine,0,CC(C)N=C1C=C2N(c3ccc(Cl)cc3)c4ccccc4N=C2C=C1Nc5ccc(Cl)cc5 +254,Colchicine,0,COC1=CC=C2C(=CC1=O)[C@H](CCc3cc(OC)c(OC)c(OC)c23)NC(C)=O +255,Cromoglicicacid,0,OC(COc1ccc2OC(=CC(=O)c2c1)C(O)=O)COc3cccc4OC(=CC(=O)c34)C(O)=O +256,Cycloserine,1,NC1CONC1=O +257,Hydroxycarbamide,1,NC(=O)NO +258,Ipratropiumbromide,0,[Br-].CC(C)[N+]1(C)C2CCC1CC(C2)OC(=O)C(CO)c3ccccc3 +259,guanabenz,0,NC(N)=N\N=C\c1c(Cl)cccc1Cl +260,guanethidinesulfate,0,NC(N)=NCCN1CCCCCCC1 +261,homatropine,0,CN1C2CCC1CC(C2)OC(=O)C(O)c3ccccc3 +262,hydralazine,0,NNc1nncc2ccccc12 +263,Hydrochlorothiazide,0,N[S](=O)(=O)c1cc2c(NCN[S]2(=O)=O)cc1Cl +264,Hydrocortisone,0,C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@](O)(C(=O)CO)[C@@]4(C)C[C@H](O)[C@H]23 +265,hydroflumethiazide,0,N[S](=O)(=O)c1cc2c(NCN[S]2(=O)=O)cc1C(F)(F)F +266,ibuprofen,0,CC(C)Cc1ccc(cc1)C(C)C(O)=O +267,indomethacin,0,COc1ccc2n(c(C)c(CC(O)=O)c2c1)C(=O)c3ccc(Cl)cc3 +268,35,0,c12c(c(ccc1)Cl)C(N(Cc1n2cnc1c1nc(on1)[C@](CO)(C)O)C)=O +269,1-47,0,NCCc1cn2c(n1)cccc2 +270,1-48,1,CCCN(CCC)CCc1ccc(c2c1CC(N2)=C)O +271,9-OH-risperidone,1,c1(c2c(cc(F)cc2)on1)C1CCN(CCc2c(n3c([C@@H](CCC3)O)nc2C)=O)CC1 +272,Alprazolam,1,Cc1nnc2CN=C(c3ccccc3)c4cc(Cl)ccc4n12 +273,BCNU,1,ClCCNC(=O)N(CCCl)N=O +274,Itraconazole,0,CCC(C)N1N=CN(C1=O)c2ccc(cc2)N3CCN(CC3)c4ccc(OC[C@H]5CO[C@@](Cn6cncn6)(O5)c7ccc(Cl)cc7Cl)cc4 +275,Kanamycin,0,NCC1OC(OC2C(N)CC(N)C(OC3OC(CO)C(O)C(N)C3O)C2O)C(O)C(O)C1O +276,Ketoprofen,1,CC(C(O)=O)c1cccc(c1)C(=O)c2ccccc2 +277,Ketorolac,0,OC(=O)C1CCn2c1ccc2C(=O)c3ccccc3 +278,Metaraminol,0,C[C@H](N)[C@H](O)c1cccc(O)c1 +279,isoniazid,0,NNC(=O)c1ccncc1 +280,Isoproterenol,0,CC(C)NCC(O)c1ccc(O)c(O)c1 +281,Isoquercitrin,0,OC[C@H]1O[C@@H](OC2=C(Oc3cc(O)cc(O)c3C2=O)c4ccc(O)c(O)c4)[C@H](O)[C@@H](O)[C@@H]1O +282,Ketoconazole,0,CC(=O)N1CCN(CC1)c2ccc(OC[C@H]3CO[C@@](Cn4ccnc4)(O3)c5ccc(Cl)cc5Cl)cc2 +283,labetalol,0,CC(CCc1ccccc1)NCC(O)c2ccc(O)c(c2)C(N)=O +284,levodopa,0,N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O +285,mannitol,0,OCC(O)C(O)C(O)C(O)CO +286,Meclocycline,0,CN(C)C1C2C(O)C3C(=C)c4c(Cl)ccc(O)c4C(=C3C(=O)C2(O)C(=O)\C(=C(N)/O)C1=O)O +287,Meclofenamate,0,Cc1ccc(Cl)c(Nc2ccccc2C(O)=O)c1Cl +288,Mefenamic_acid,0,Cc1cccc(Nc2ccccc2C(O)=O)c1C +289,Cimetidine,0,CN=C(NCCSCc1nc[nH]c1C)NC#N +290,Clonidine,1,Clc1cccc(Cl)c1NC2=NCCN2 +291,Didanosine,0,OC[C@@H]1CC[C@@H](O1)n2cnc3C(=O)N=CNc23 +292,Metoprolol,1,COCCc1ccc(OCC(O)CNC(C)C)cc1 +293,Metronidazole,1,Cc1ncc(n1CCO)[N+]([O-])=O +294,Mifepristone,0,CC#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c5ccc(cc5)N(C)C +295,Minocycline,1,C1[C@@H]2[C@](C(=C3C(c4c(ccc(c4C[C@@H]13)N(C)C)O)=O)O)(C(C(C(N)=O)=C([C@H]2N(C)C)O)=O)O +296,Moclobemide,1,Clc1ccc(cc1)C(=O)NCCN2CCOCC2 +297,Propanthelinebromide,0,[Br-].CC(C)[N+](C)(CCOC(=O)C1c2ccccc2Oc3ccccc13)C(C)C +298,Pyrazinamide,1,NC(=O)c1cnccn1 +299,Pyridostigminebromide,1,[Br-].CN(C)C(=O)Oc1ccc[n+](C)c1 +300,Pyrimethamine,1,CCc1nc(N)nc(N)c1c2ccc(Cl)cc2 +301,Quinine,0,COc1ccc2nccc([C@@H](O)[C@@H]3C[C@H]4CCN3C[C@@H]4C=C)c2c1 +302,melphalan,0,NC(Cc1ccc(cc1)N(CCCl)CCCl)C(O)=O +303,mepenzolatebromide,0,[Br-].C[N+]1(C)CCCC(C1)OC(=O)C(O)(c2ccccc2)c3ccccc3 +304,mepiramine,0,COc1ccc(CN(CCN(C)C)c2ccccn2)cc1 +305,mequitazine,0,C1CN2CCC1C(C2)CN3c4ccccc4Sc5ccccc35 +306,mestranol,0,COc1ccc2[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]4(O)C#C)[C@@H]3CCc2c1 +307,methantheline,0,CC[N+](C)(CC)CCOC(=O)C1c2ccccc2Oc3ccccc13 +308,methotrexate,0,CN(Cc1cnc2nc(N)nc(N)c2n1)c3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O +309,Methyclothiazide,0,CN1C(CCl)Nc2cc(Cl)c(cc2[S]1(=O)=O)[S](N)(=O)=O +310,methyldopa,0,C[C@](N)(Cc1ccc(O)c(O)c1)C(O)=O +311,Icotidine,0,[Cl-].[Cl-].[Cl-].COc1cccnc1CCCCNC2=NC=C(Cc3ccc(C)nc3)C(=O)N2.[H+].[H+].[H+] +312,L-663581,1,CC(C)c1onc(n1)c2ncn3c2CN(C)C(=O)c4c(Cl)cccc34 +313,Lupitidine,0,Cc1ccc(CC2=CN=C(NCCSCc3oc(cc3)C(C)(C)N)NC2=O)cn1 +314,Mianserin,1,CN1CCN2C(C1)c3ccccc3Cc4ccccc24 +315,Midazolam,1,Cc1ncc2CN=C(c3ccccc3F)c4cc(Cl)ccc4n12 +316,Ritonavir,0,CC(C)[C@H](NC(=O)N(C)Cc1csc(n1)C(C)C)C(=O)N[C@H](C[C@H](O)[C@H](Cc2ccccc2)NC(=O)OCc3scnc3)Cc4ccccc4 +317,Saquinavir,0,CC(C)(C)NC(=O)[C@@H]1C[C@@H]2CCCC[C@@H]2CN1C[C@@H](O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(N)=O)NC(=O)c4ccc5ccccc5n4 +318,Sevoflurane,1,FCOC(C(F)(F)F)C(F)(F)F +319,Sodiumamidotrizoate,0,[Na+].CC(=O)Nc1c(I)c(NC(C)=O)c(I)c(C([O-])=O)c1I +320,Sotalol,1,CC(C)NCC(O)c1ccc(N[S](C)(=O)=O)cc1 +321,Stavudine,1,CC1=CN([C@@H]2O[C@H](CO)C=C2)C(=O)NC1=O +322,Streptomycin,0,CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@H]2[C@@H](O[C@@H](C)[C@]2(O)C=O)O[C@H]3[C@H](O)[C@@H](O)[C@H](N=C(N)N)[C@@H](O)[C@@H]3N=C(N)N +323,Sulfadiazine,1,Nc1ccc(cc1)[S](=O)(=O)Nc2ncccn2 +324,Sulfafurazole,1,Cc1noc(N[S](=O)(=O)c2ccc(N)cc2)c1C +325,Methylprednisolone,0,C[C@H]1C[C@H]2[C@@H]3CC[C@](O)(C(=O)CO)[C@@]3(C)C[C@H](O)[C@@H]2[C@@]4(C)C=CC(=O)C=C14 +326,Miconazole,0,Clc1ccc(COC(Cn2ccnc2)c3ccc(Cl)cc3Cl)c(Cl)c1 +327,nandrolone,0,C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@H]2O +328,neodicoumarol,0,CCOC(=O)C(C1=C(O)Oc2ccccc2C1=O)C3=C(O)Oc4ccccc4C3=O +329,Nicotinyl alcohol,0,OCc1cccnc1 +330,norethindrone,0,C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@H]34)[C@@H]1CC[C@@]2(O)C#C +331,norfenefrine,0,NCC(O)c1cccc(O)c1 +332,nylidrin,0,CC(CCc1ccccc1)NC(C)C(O)c2ccc(O)cc2 +333,Oxandrolone,0,C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4CC(=O)OC[C@]4(C)[C@H]3CC[C@]12C +334,Oxaprozin,0,OC(=O)CCc1oc(c2ccccc2)c(n1)c3ccccc3 +335,Mirtazapine,1,CN1CCN2C(C1)c3ccccc3Cc4cccnc24 +336,Nevirapine,1,Cc1ccnc2N(C3CC3)c4ncccc4C(=O)Nc12 +337,Org12962,1,C1NCCN(C1)c1ccc(c(n1)Cl)C(F)(F)F +338,Org30526,1,c1c2c(cc(c1)Cl)[C@@H]1[C@H](c3ccccc3O2)CNC1 +339,Org32104,1,c1c2c(ccc1)[C@@]1([C@@H](c3cccc(c3O2)C)CNCC1)O +340,Org34167,1,c1ccc(c(c1)[C@H](CC=C)N)c1c2c(on1)cccc2 +341,Org4428,1,c1c2c(ccc1)[C@@]1([C@@H](c3cccc(c3O2)C)C[N@](CC1)C)O +342,Org5222,1,c1c2c(cc(c1)Cl)[C@@H]1[C@H](c3ccccc3O2)CN(C1)C +343,Ranitidine,0,CNC(/NCCSCc1oc(CN(C)C)cc1)=C\[N+]([O-])=O +344,Sulfamethoxazole,1,Cc1onc(N[S](=O)(=O)c2ccc(N)cc2)c1 +345,Tamoxifen,1,CC/C(c1ccccc1)=C(c2ccccc2)/c3ccc(OCCN(C)C)cc3 +346,Ticarcillin,1,[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](C([O-])=O)c3cscc3)C(=O)N2[C@H]1C([O-])=O +347,Topotecan,1,CC[C@@]1(O)C(=O)OCC2=C1C=C3N(Cc4cc5c(CN(C)C)c(O)ccc5nc34)C2=O +348,Zalcitabine,1,NC1=NC(=O)N(C=C1)[C@H]2CC[C@@H](CO)O2 +349,Zonisamide,1,N[S](=O)(=O)Cc1noc2ccccc12 +350,AmphotericinB,0,C[C@H]1O[C@@H](O[C@@H]\2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C/C=C\C=C/C=C\C=C/C=C\C=C2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O +351,Calcium-folinate,1,[Ca++].NC1=NC(=O)C2=C(NCC(CNc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)N2C=O)N1 +352,oxytetracycline,0,O.O.CN(C)[C@H]1[C@@H]2[C@@H](O)[C@H]3C(=C(O)c4c(O)cccc4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(N)/O)C1=O +353,papaverine,0,COc1ccc(Cc2nccc3cc(OC)c(OC)cc23)cc1OC +354,penicillin G,0,CC1(C)S[C@@H]2[C@H](NC(=O)Cc3ccccc3)C(=O)N2[C@H]1C(O)=O +355,phenacetin,0,CCOc1ccc(NC(C)=O)cc1 +356,phenazopyridine,0,Nc1ccc(N=Nc2ccccc2)c(N)n1 +357,pheniramine,0,CN(C)CCC(c1ccccc1)c2ccccn2 +358,Phenolphthalein,0,Oc1ccc(cc1)C2(OC(=O)c3ccccc23)c4ccc(O)cc4 +359,phenoxybenzamine,0,CC(COc1ccccc1)N(CCCl)Cc2ccccc2 +360,Phenylbutazone,0,CCCCC1C(=O)N(N(C1=O)c2ccccc2)c3ccccc3 +361,pirbuterol,0,CC(C)(C)NCC(O)c1ccc(O)c(CO)n1 +362,Risperidone,1,CC1=C(CCN2CCC(CC2)c3noc4cc(F)ccc34)C(=O)N5CCCCC5=N1 +363,Phenserine,1,CN1CC[C@]2(C)[C@H]1N(C)c3ccc(OC(=O)Nc4ccccc4)cc23 +364,Temelastine,0,Cc1ccc(CC2=CN=C(NCCCCc3ncc(Br)cc3C)NC2=O)cn1 +365,Tibolone,1,C[C@@H]1CC2=C(CCC(=O)C2)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]4(O)C#C)[C@H]13 +366,Ceftazidime,1,CC(C)(O/N=C(C(=O)N[C@H]1[C@H]2SCC(=C(N2C1=O)C([O-])=O)C[n+]3ccccc3)/c4csc(N)n4)C(O)=O +367,Flucytosine,1,NC1=C(F)C=NC(=O)N1 +368,Guanadrel,0,NC(N)=NCC1COC2(CCCCC2)O1 +369,Lomustine,1,ClCCN(N=O)C(=O)NC1CCCCC1 +370,Mesna,0,[Na+].[O-][S](=O)(=O)CCS +371,Streptozotocin,0,CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O +372,Teniposide,1,COc1cc(cc(OC)c1O)[C@H]2[C@@H]3[C@H](COC3=O)[C@H](OC4OC5COC(OC5C(O)C4O)c6sccc6)c7cc8OCOc8cc27 +373,Thiotepa,1,S=[P](N1CC1)(N2CC2)N3CC3 +374,Vancomycin,0,CN[C@H](CC(C)C)C(=O)NC1[C@H](O)c2ccc(Oc3cc4cc(Oc5ccc(cc5Cl)[C@@H](O)[C@@H]6NC(=O)[C@H](NC(=O)[C@@H]4NC(=O)[C@H](CC(N)=O)NC1=O)c7ccc(O)c(c7)c8c(O)cc(O)cc8[C@@H](NC6=O)C(O)=O)c3O[C@@H]9O[C@H](CO)[C@@H](O)[C@H](O)[C@H]9O[C@H]%10C[C@](C)(N)[C@H](O)[C@H](C)O%10)c(Cl)c2 +375,Polythiazide,0,CN1C(CSCC(F)(F)F)Nc2cc(Cl)c(cc2[S]1(=O)=O)[S](N)(=O)=O +376,prednisolone,0,C[C@]12C[C@H](O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO +377,prednisone,0,C[C@]12CC(=O)[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CC[C@]2(O)C(=O)CO +378,probenecid,0,CCCN(CCC)[S](=O)(=O)c1ccc(cc1)C(O)=O +379,progesterone,0,CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C +380,propranolol,0,CC(C)NCC(O)COc1cccc2ccccc12 +381,proscillaridin,0,CC1OC(O[C@H]2CC[C@]3(C)[C@H]4CC[C@]5(C)[C@H](CC[C@]5(O)[C@@H]4CCC3=C2)C6=COC(=O)C=C6)C(O)C(O)C1O +382,puromycin,0,COc1ccc(C[C@H](N)C(=O)NC2[C@@H](O)[C@@H](O[C@@H]2CO)n3cnc4c(ncnc34)N(C)C)cc1 +383,ribavirin,0,NC(=O)c1ncn(n1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O +384,Tiotidine,1,CN=C(NCCSCc1csc(N=C(N)N)n1)NC#N +385,Zolantidine,1,OC(=O)\C=C/C(O)=O.OC(=O)\C=C/C(O)=O.C1CCN(CC1)Cc2cccc(OCCCNc3sc4ccccc4n3)c2 +386,1-hydroxymidazolam,1,OCc1ncc2CN=C(c3ccccc3F)c4cc(Cl)ccc4n12 +387,111-trichloroethane,1,CC(Cl)(Cl)Cl +388,111-trifluoro-2-chloroethane,1,C(CCl)(F)(F)F +389,2-methylpropanol,1,CC(C)CO +390,"""2,2-dimethylbutane""",1,CCC(C)(C)C +391,Vidarabine,1,Nc1ncnc2n(cnc12)C3OC(CO)C(O)C3O +392,Bis-hydroxylated-L-663581,0,c12c(C(N(Cc3n1cnc3c1noc(n1)C(CO)(CO)C)C)=O)c(ccc2)Cl +393,ICI17148,1,Cc1nc(sc1)\[NH]=C(\N)N +394,Mono-hydroxylated-L-663581,0,c12c(C(N(Cc3n1cnc3c1noc(n1)C(O)(C)C)C)=O)c(ccc2)Cl +395,Thioperamide,1,S=C(NC1CCCCC1)N2CCC(CC2)c3[nH]cnc3 +396,rifampin,0,CC1C=CC=C(C(=O)NC2=C(C3=C(C(=C4C(=C3C(=O)C2=CNN5CCN(CC5)C)C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)C +397,salicylic acid,0,OC(=O)c1ccccc1O +398,scopolamine,0,CN1[C@@H]2CC(C[C@H]1[C@@H]3O[C@H]23)OC(=O)[C@H](CO)c4ccccc4 +399,Spironolactone,0,CC(=O)S[C@@H]1CC2=CC(=O)CC[C@]2(C)[C@H]3CC[C@@]4(C)[C@@H](CC[C@@]45CCC(=O)O5)[C@H]13 +400,Stanozolol,0,C[C@]1(O)CC[C@H]2[C@@H]3CC[C@H]4Cc5[nH]ncc5C[C@]4(C)[C@H]3CC[C@]12C +401,sulfasalazine,0,OC(=O)C1=C\C(C=CC1=O)=N/Nc2ccc(cc2)[S](=O)(=O)Nc3ccccn3 +402,Terconazole,0,CC(C)N1CCN(CC1)c2ccc(OC[C@H]3CO[C@@](Cn4cncn4)(O3)c5ccc(Cl)cc5Cl)cc2 +403,testolactone,0,C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1CCC(=O)O2 +404,testosterone,0,C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O +405,TetraCycline,0,CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)c4c(O)cccc4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(N)/O)C1=O +406,3-methylhexane,1,CCCC(C)CC +407,3-methylpentane,1,CCC(C)CC +408,4-hydroxymidazolam,1,Cc1ncc2C(O)N=C(c3ccccc3F)c4cc(Cl)ccc4n12 +409,Aminopyrine,1,CN(C)C1=C(C)N(C)N(c2ccccc2)C1=O +410,Atenolol,0,CC(C)NCC(O)COc1ccc(CC(N)=O)cc1 +411,Benzene,1,c1ccccc1 +412,Bretazenil,1,CC(C)(C)OC(=O)c1ncn2c3cccc(Br)c3C(=O)N4CCC[C@H]4c12 +413,Bromperidol,1,OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Br)cc3 +414,Mefloquine,1,OC(C1CCCCN1)c2cc(nc3c2cccc3C(F)(F)F)C(F)(F)F +415,Ofloxacin,1,CC1COc2c(N3CCN(C)CC3)c(F)cc4C(=O)C(=CN1c24)C(O)=O +416,Tifluadom,1,CN1C(CNC(=O)c2cscc2)CN=C(c3ccccc3F)c4ccccc14 +417,aldosterone,0,C[C@]12CCC(=O)C=C1CC[C@H]3[C@@H]4CC[C@H](C(=O)CO)[C@]4(C[C@H](O)[C@H]23)C=O +418,BRL52537,1,c1(cc(c(cc1)Cl)Cl)CC(N1CCCC[C@H]1CN1CCCC1)=O +419,BRL52580,1,c1(cc(c(cc1)Cl)Cl)CC(N1[C@@H](c2c(CC1)cccc2)CN1CCCC1)=O +420,BRL52656,1,c1(ccc(cc1)C(F)(F)F)CC(N1[C@@H](CCCC1)CN1CCCC1)=O +421,BRL52871,1,c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)scc2)CN1CCCC1)=O +422,theophylline,0,CN1C(=O)N(C)c2nc[nH]c2C1=O +423,thioguanine,0,NC1=NC(=S)c2[nH]cnc2N1 +424,tolazamide,0,Cc1ccc(cc1)[S](=O)(=O)NC(=O)NN2CCCCCC2 +425,tolbutamide,0,CCCCNC(=O)N[S](=O)(=O)c1ccc(C)cc1 +426,Triamcinolone,0,C[C@]12C[C@H](O)[C@@]3(F)[C@@H](CCC4=CC(=O)C=C[C@]34C)[C@@H]1C[C@@H](O)[C@]2(O)C(=O)CO +427,Triamterene,0,Nc1nc(N)c2nc(c3ccccc3)c(N)nc2n1 +428,Trichlormethiazide,0,N[S](=O)(=O)c1cc2c(NC(N[S]2(=O)=O)C(Cl)Cl)cc1Cl +429,valinomycin,0,CC(C)[C@@H]1NC(=O)[C@H](C)OC(=O)C(NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC(=O)[C@@H](NC(=O)[C@H](C)OC(=O)[C@H](NC(=O)[C@H](OC1=O)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C)C(C)C +430,verapamil,0,COc1ccc(CCN(C)CCCC(C#N)(C(C)C)c2ccc(OC)c(OC)c2)cc1OC +431,warfarin,0,CC(=O)CC(c1ccccc1)C2=C(O)Oc3ccccc3C2=O +432,Butanone,1,CCC(C)=O +433,Cyclopropane,1,C1CC1 +434,Desmethyldesipramine,1,N1(c2c(CCc3c1cccc3)cccc2)CCCN +435,Dichloromethane,1,ClCCl +436,Diethylether,1,CCOCC +437,Divinylether,1,C=COC=C +438,Enflurane,1,FC(F)OC(F)(F)C(F)Cl +439,BRL52974,0,c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)[nH]cn2)CN1CCCC1)=O +440,BRL53087,1,c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](CN2CCCC2)CC(CC1)(C)C)=O +441,carebastine,0,CC(C)(C(O)=O)c1ccc(cc1)C(=O)CCCN2CCC(CC2)OC(c3ccccc3)c4ccccc4 +442,cetirizine,0,OC(=O)COCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 +443,ciprofloxacin,0,OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O +444,cp102,0,c1cn(CCO)c(CC)c(O)c1=O +445,cp107,0,c1cn(CCCCO)c(CC)c(O)c1=O +446,yohimbine,0,COC(=O)[C@H]1[C@@H](O)CC[C@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 +447,zidovudine,0,CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O +448,acepromazine,1,CN(C)CCCN1c2ccccc2Sc3ccc(cc13)C(C)=O +449,acetophenazine,1,CC(=O)c1ccc2Sc3ccccc3N(CCCN4CCN(CCO)CC4)c2c1 +450,acetozalamide,1,CC(=O)Nc1sc(nn1)[S](N)(=O)=O +451,allobarbital,1,C=CCC1(CC=C)C(=O)NC(=O)NC1=O +452,amantadine,1,[Cl-].NC12CC3CC(CC(C3)C1)C2.[H+] +453,amitriptyline,1,CN(C)CCC=C1c2ccccc2CCc3ccccc13 +454,amobarbital,1,CCC1(CCC(C)C)C(=O)NC(=O)NC1=O +455,amphetamine,1,CC(N)Cc1ccccc1 +456,Ethanol,1,CCO +457,Ethylbenzene,1,CCc1ccccc1 +458,Flumazenil,1,CCOC(=O)c1ncn2c1CN(C)C(=O)c3cc(F)ccc23 +459,Flunitrazepam,1,CN1C(=O)CN=C(c2ccccc2F)c3cc(ccc13)[N+]([O-])=O +460,Fluroxene,1,FC(F)(F)COC=C +461,Halothane,1,FC(F)(F)C(Cl)Br +462,Heptane,1,CCCCCCC +463,Hexane,1,CCCCCC +464,cp20,1,CN1C=CC(=O)C(=C1C)O +465,cp21,1,CCN1C=CC(=O)C(=C1C)O +466,cp24,1,CCCCN1C=CC(=O)C(=C1C)O +467,cp25,1,CCCCCN1C=CC(=O)C(=C1C)O +468,cp29,1,c1cn(CCCCC)c(C)c(O)c1=O +469,cp41,0,c1cn(CCCO)c(C)c(O)c1=O +470,cp94,1,CCN1C=CC(=O)C(=C1CC)O +471,difloxacin,0,CN1CCN(CC1)c2cc3N(C=C(C(O)=O)C(=O)c3cc2F)c4ccc(F)cc4 +472,antipyrine,1,CN1N(C(=O)C=C1C)c2ccccc2 +473,apomorphine,1,CN1CCc2cccc3c2[C@H]1Cc4ccc(O)c(O)c34 +474,arecoline,1,COC(=O)C1=CCCN(C)C1 +475,azaperone,1,Fc1ccc(cc1)C(=O)CCCN2CCN(CC2)c3ccccn3 +476,benactyzine,1,[H+].[Cl-].CCN(CC)CCOC(=O)C(O)(c1ccccc1)c2ccccc2 +477,benperidol,1,Fc1ccc(cc1)C(=O)CCCN2CCC(CC2)N3C(=O)Nc4ccccc34 +478,benzocaine,1,CCOC(=O)c1ccc(N)cc1 +479,benzquinamide,1,CCN(CC)C(=O)C1CN2CCc3cc(OC)c(OC)cc3C2CC1OC(C)=O +480,benztropine,1,CN1C2CCC1CC(C2)OC(c3ccccc3)c4ccccc4.O[S](O)(=O)=O +481,biperiden,1,OC(CCN1CCCCC1)(C2CC3CC2C=C3)c4ccccc4 +482,Hexobarbital,1,CN1C(=O)NC(=O)C(C)(C1=O)C2=CCCCC2 +483,Indinavir,1,CC(C)(C)NC(=O)[C@@H]1CN(CCN1C[C@@H](O)C[C@@H](Cc2ccccc2)C(=O)N[C@@H]3[C@H](O)Cc4ccccc34)Cc5cccnc5 +484,Isoflurane,1,FC(F)OC(Cl)C(F)(F)F +485,Methohexital,1,CCC#CC(C)C1(CC=C)C(=O)NC(=O)N(C)C1=O +486,Methoxyflurane,1,COC(F)(F)C(Cl)Cl +487,Methylcyclopentane,1,CC1CCCC1 +488,Nor-1-chlorpromazine,1,N1(c2c(Sc3c1cccc3)ccc(c2)Cl)CCCNC +489,Nor-2-chlorpromazine,1,N1(c2c(Sc3c1cccc3)ccc(c2)Cl)CCCN +490,doxylamine,1,CN(C)CCOC(C)(c1ccccc1)c2ccccn2 +491,EMD60400,0,c1ccc([C@H](C[N@]2CC[C@H](C2)O)N(C(Cc2ccccc2N)=O)C)cc1 +492,enoxacin,0,CCN1C=C(C(O)=O)C(=O)c2cc(F)c(nc12)N3CCNCC3 +493,fleroxacin,0,CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN(CCF)c3c2F)C(O)=O +494,GR85571,1,c1(cc(c(cc1)Cl)Cl)CC(N1[C@@H](CN2CCCC2)CN(CC1)C(=O)C)=O +495,GR88377,1,c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)occ2)CN1CCCC1)=O +496,GR89696,1,c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN(CC1)C(=O)OC)CN1CCCC1)=O +497,bromazepam,1,Brc1ccc2NC(=O)CN=C(c3ccccn3)c2c1 +498,buclizine,1,CC(C)(C)c1ccc(CN2CCN(CC2)C(c3ccccc3)c4ccc(Cl)cc4)cc1 +499,bufotenine,1,CN(C)CCc1c[nH]c2ccc(O)cc12 +500,bupropion,1,CC(NC(C)(C)C)C(=O)c1cccc(Cl)c1 +501,buramate,1,OCCOC(=O)NCc1ccccc1 +502,butabarbital,1,CCC(C)C1(CC)C(=O)NC(=O)NC1=O +503,caffeine,1,Cn1cnc2N(C)C(=O)N(C)C(=O)c12 +504,cannabidiol,1,CCCCCc1cc(O)c(C2C=C(C)CC[C@H]2C(C)=C)c(O)c1 +505,capuride,1,CCC(C)C(CC)C(=O)NC(N)=O +506,carbamazepine,1,NC(=O)N1c2ccccc2C=Cc3ccccc13 +507,Northioridazine,1,CSc1ccc2Sc3ccccc3N(CCC4CCCNC4)c2c1 +508,Org13011,1,C1N(CCN(C1)c1cc(ccn1)C(F)(F)F)CCCCN1C(CCC1)=O +509,Paraxanthine,1,Cn1cnc2NC(=O)N(C)C(=O)c12 +510,Pentane,1,CCCCC +511,Propanol,1,CCCO +512,Propanone,1,CC(C)=O +513,GR89696_et,1,c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN(CC1)C(=O)OCC)CN1CCCC1)=O +514,GR89696_pr,1,c1(CC(N2[C@H](CN(CC2)C(=O)OCCC)CN2CCCC2)=O)cc(c(cc1)Cl)Cl +515,GR91272,1,c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](c2c(CC1)occ2)C[N@@]1C[C@@H](CC1)O)=O +516,GR94839,0,c1(ccc(c(c1)Cl)Cl)CC(=O)N1[C@H](CN(C(=O)C)CC1)C[N@@]1C[C@H](O)CC1 +517,GR94839_A,0,c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)ccc(C(F)(F)F)cc1 +518,GR94839_B,0,c1(ccc(cc1)SC)CC(N1[C@H](CN(CC1)C(=O)C)C[N@]1CC[C@H](C1)O)=O +519,GR94839_C,0,c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)cc(cc(c1)F)F +520,GR94839_D,0,c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)cc(ccc1)OC +521,GR94839_E,0,c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc(N(=O)=O)cc1 +522,GR94839_F,0,c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](C2)O)=O)ccc(OC)cc1 +523,carphenazine,1,CCC(=O)c1ccc2Sc3ccccc3N(CCCN4CCN(CCO)CC4)c2c1 +524,cartazolate,1,CCCCNc1c(cnc2n(CC)ncc12)C(=O)OCC +525,centazolone,1,NN1C=Nc2cc3ccccc3cc2C1=O +526,chloralhydrate,1,OC(O)C(Cl)(Cl)Cl +527,chlordiazepoxide,1,CN=C1CN(O)C(=C2C=C(Cl)C=CC2=N1)c3ccccc3 +528,chlorpromazine,1,CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13 +529,chlorprothixene,1,CN(C)CC\C=C/1c2ccccc2Sc3ccc(Cl)cc13 +530,chlorzoxazone,1,Clc1ccc2OC(=O)Nc2c1 +531,choline,1,C[N+](C)(C)CCO +532,clobazam,1,CN1C(=O)CC(=O)N(c2ccccc2)c3cc(Cl)ccc13 +533,RO19-4603,1,CN1Cc2n(cnc2C(=O)OC(C)(C)C)c3ccsc3C1=O +534,SKF101468,1,C1C(Nc2c1c(ccc2)CCN(CCC)CCC)=O +535,SKF89124,1,C1C(Nc2c1c(ccc2O)CCN(CCC)CCC)=O +536,Salicyluricacid,1,OC(=O)CNC(=O)c1ccccc1O +537,Sulforidazine,1,CN1CCCCC1CCN2c3ccccc3Sc4ccc(cc24)[S](C)(=O)=O +538,Teflurane,1,FC(Br)C(F)(F)F +539,Theobromine,1,Cn1cnc2N(C)C(=O)NC(=O)c12 +540,Thiopental,0,CCCC(C)C1(CC)C(=O)NC(=S)NC1=O +541,Toluene,1,Cc1ccccc1 +542,Triazolam,1,Cc1nnc2CN=C(c3ccccc3Cl)c4cc(Cl)ccc4n12 +543,GR94839_G,0,c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)cc(ccc1)N(=O)=O +544,GR94839_H,0,c1(ccccc1)CC(N1[C@H](CN(CC1)C(=O)C)C[N@]1CC[C@H](C1)O)=O +545,GR94839_I,0,c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc([S@](=O)C)cc1 +546,GR94839_L,0,c1(CC(N2[C@H](CN(CC2)C(=O)C)C[N@]2CC[C@H](O)C2)=O)ccc(S(=O)(=O)C)cc1 +547,ICI197067,1,CC(C)[C@@H](CN1CCCC1)N(C)C(=O)Cc2ccc(Cl)c(Cl)c2 +548,ICI199441,1,c1(ccccc1)[C@H](CN1CCCC1)N(C(=O)Cc1ccc(c(c1)Cl)Cl)C +549,isoxicam,0,CN1C(=C(\O)Nc2cc(C)on2)/C(=O)c3ccccc3[S]1(=O)=O +550,Levallorphan,1,Oc1ccc2C[C@@H]3[C@@H]4CCCC[C@]4(CCN3CC=C)c2c1 +551,lomefloxacin,0,CCN1C=C(C(O)=O)C(=O)c2cc(F)c(N3CCNC(C)C3)c(F)c12 +552,loperamide,0,CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4 +553,clomipramine,1,CN(C)CCCN1c2ccccc2CCc3ccc(Cl)cc13 +554,clonazepam,1,[O-][N+](=O)c1ccc2NC(=O)CN=C(c3ccccc3Cl)c2c1 +555,clopenthixol,1,OCCN1CCN(CC\C=C/2c3ccccc3Sc4ccc(Cl)cc24)CC1 +556,clopimozide,1,Fc1ccc(cc1)C(CCCN2CCC(CC2)N3C(=O)Nc4cc(Cl)ccc34)c5ccc(F)cc5 +557,cocaine,1,COC(=O)[C@H]1[C@H](CC2CCC1N2C)OC(=O)c3ccccc3 +558,codeine,1,COc1ccc2C[C@@H]3[C@@H]4C=C[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C +559,cyclazocine,1,CC1C2Cc3ccc(O)cc3C1(C)CCN2CC4CC4 +560,cyclophenazine,1,FC(F)(F)c1ccc2Sc3ccccc3N(CCCN4CCN(CC4)C5CC5)c2c1 +561,deanol,1,CN(C)CCO +562,demerol,1,[H+].[Cl-].CCOC(=O)C1(CCN(C)CC1)c2ccccc2 +563,Trichloroethylene,1,ClC=C(Cl)Cl +564,Trichloromethane,1,ClC(Cl)Cl +565,Y-G14,1,c1c(nccc1)CCNC +566,Y-G15,1,c1c(nccc1)CCN(C)C +567,Y-G16,1,n1c(scc1)CCN +568,Y-G19,0,n1c(scc1c1ccccc1)CCN +569,Y-G20,0,c1c(nc2n1cccc2)CCN +570,m-Xylene,1,Cc1cccc(C)c1 +571,loratadine,0,CCOC(=O)N1CCC(CC1)=C2c3ccc(Cl)cc3CCc4cccnc24 +572,meloxicam,0,CN1C(=C(/O)Nc2sc(C)cn2)/C(=O)c3ccccc3[S]1(=O)=O +573,Nalorphine,1,O[C@H]1C=C[C@H]2[C@H]3Cc4ccc(O)c5O[C@@H]1[C@]2(CCN3CC=C)c45 +574,naltrexone,1,Oc1ccc2C[C@H]3N(CC[C@@]45[C@@H](Oc1c24)C(=O)CC[C@@]35O)CC6CC6 +575,norfloxacin,0,CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCNCC3 +576,pefloxacin,0,CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCN(C)CC3 +577,piroxicam,0,CN1C(=C(/O)Nc2ccccn2)/C(=O)c3ccccc3[S]1(=O)=O +578,roxindole,1,C[S](O)(=O)=O.Oc1ccc2[nH]cc(CCCCN3CCC(=CC3)c4ccccc4)c2c1 +579,deserpidine,1,CO[C@H]1[C@@H](C[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@H]3C[C@@H]2[C@@H]1C(=O)OC)OC(=O)c6cc(OC)c(OC)c(OC)c6 +580,desipramine,1,CNCCCN1c2ccccc2CCc3ccccc13 +581,diazepam,1,CN1C(=O)CN=C(c2ccccc2)c3cc(Cl)ccc13 +582,dihydrocodeine,1,COc1ccc2C[C@@H]3[C@@H]4CC[C@H](O)[C@@H]5Oc1c2[C@]45CCN3C +583,dihydromorphine,1,CN1CCC23C4CCC(O)C2Oc5c(O)ccc(CC14)c35 +584,diphenhydramine,1,CN(C)CCOC(c1ccccc1)c2ccccc2 +585,diphenhylhydantoin,1,O=C1NC(=O)C(N1)(c2ccccc2)c3ccccc3 +586,dixyrazine,1,CC(CN1CCN(CCOCCO)CC1)CN2c3ccccc3Sc4ccccc24 +587,DMT,1,COC(=O)c1ccc(cc1)C(=O)OC +588,o-Xylene,1,Cc1ccccc1C +589,p-Xylene,1,Cc1ccc(C)cc1 +590,2-propanol,1,CC(C)O +591,Carbamazepineepoxide,1,NC(=O)N1c2ccccc2C3OC3c4ccccc14 +592,SB-222200,1,c12c(nc(c(c1C(N[C@@H](CC)c1ccccc1)=O)C)c1ccccc1)cccc2 +593,Tertbutylchlorambucil,1,c1cc(ccc1CCCC(OC(C)(C)C)=O)N(CCCl)CCCl +594,Delavirdine,0,CC(C)Nc1cccnc1N2CCN(CC2)C(=O)c3[nH]c4ccc(N[S](C)(=O)=O)cc4c3 +595,Ebastine,0,CC(C)(C)c1ccc(cc1)C(=O)CCCN2CCC(CC2)OC(c3ccccc3)c4ccccc4 +596,Pirenzepine,1,CN1CCN(CC1)CC(=O)N2c3ccccc3C(=O)Nc4cccnc24 +597,RP60180,1,c1ccc2N([C@H](CN3CCCC3)C)c3c(ccc(C(=O)NCCC)c3)Sc2c1 +598,rufloxacin,0,CN1CCN(CC1)c2c(F)cc3C(=O)C(=CN4CCSc2c34)C(O)=O +599,salbutamol,0,CC(C)(C)NCC(O)c1ccc(O)c(CO)c1 +600,Sankyo,1,c1(ccc(c(c1)Cl)Cl)CC(=O)N1[C@H](C[N@@](C)CC1)CN1CCCC1 +601,SB201708,1,c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN2CCCC2)c2n(CC1)ccn2)=O +602,SB204454,0,c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](C[C@]2(CC1)NC(NC2=O)=O)CN1CCCC1)=O +603,SB204459,0,c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](C[N@@]2C[C@@H](CC2)O)c2n(CC1)ccn2)=O +604,SB204484,1,c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](CN2CCCC2)c2n(CC1)ncn2)=O +605,SB205563,0,c1(ccc(c(c1)Cl)Cl)CC(N1[C@@H](C[N@@]2C[C@@H](CC2)O)C[N@](CC1)CCO)=O +606,doxepin,1,[H+].[Cl-].CN(C)CC\C=C/1c2ccccc2COc3ccccc13 +607,doxylamine succinate,1,CN(C)CCOC(C)(c1ccccc1)c2ccccn2.OC(=O)CCC(O)=O +608,droperidol,1,Fc1ccc(cc1)C(=O)CCCN2CCC(=CC2)N3C(=O)Nc4ccccc34 +609,ectylurea,1,CC\C(=C/C)C(=O)NC(N)=O +610,emylcamate,1,CCC(C)(CC)OC(N)=O +611,estazolam,1,Clc1ccc2n3cnnc3CN=C(c4ccccc4)c2c1 +612,etaqualone,1,CCc1ccccc1N2C(=Nc3ccccc3C2=O)C +613,etazolate,1,CCOC(=O)c1cnc2n(CC)ncc2c1NN=C(C)C +614,ethchlorvynol,1,CCC(O)(\C=C\Cl)C#C +615,ethinamate,1,NC(=O)OC1(CCCCC1)C#C +616,5-6,1,s1cc(CSCCN\C(NC)=[NH]\C#N)nc1\[NH]=C(\N)N +617,5-66,1,c1cc(CCNC)ncc1 +618,5-67,1,c1cc(CCN(C)C)ncc1 +619,5-68,1,s1c(ncc1)CCN +620,5-69,1,c1nc(C2CCN(CC2)C(NC2CCCCC2)=S)c[nH]1 +621,7-K06,1,c1ccc2Oc3c(cc(cc3)Cl)[C@@H]3[C@@H](c2c1)C[N@](CC3)C +622,7-K08,1,c1c(Cl)nc(N2CCN(CCCCN3C(CCC3)=O)CC2)cc1C(F)(F)F +623,7-K10,1,c1ccc2Oc3c(cc(cc3)Cl)[C@@H]3[C@@H](c2c1)CNCC3 +624,SB205605,0,c1(ccc(c(c1)Cl)Cl)CC(N1[C@H](C[N@@]2C[C@@H](CC2)O)c2c(CC1)[nH]cn2)=O +625,skb_a,1,c1ccc2nc(c(c(C(N[C@@H](CC)c3ccccc3)=O)c2c1)O)c1ccccc1 +626,skb_c,1,c1cc2c(C(N[C@@H](CC)c3ccccc3)=O)c(c(nc2cc1)c1ccccc1)OCCCN(C)C +627,skb-d,0,c1cc2c(C(N[C@@H](CC)c3ccccc3)=O)c(c(nc2cc1)c1ccccc1)OCC(O)=O +628,skb-e,0,c1cc2c(C(N[C@@H](CC)c3ccccc3)=O)c(c(c3ccccc3)nc2cc1)OCCCC(O)=O +629,skb-f,0,c1ccc2c(c(C(N[C@@H](CC)c3ccccc3)=O)c(OCCNC(Cc3c(cccc3)C(=O)O)=O)c(c3ccccc3)n2)c1 +630,skb-g,0,c1cc2c(c(OCCNC(Cc3ncccc3)=O)c(c3ccccc3)nc2cc1)C(N[C@@H](CC)c1ccccc1)=O +631,skb-h,0,c1cc2c(c(c(c3ccccc3)nc2cc1)OCCNC([C@@H]1CCCN1)=O)C(=O)N[C@@H](CC)c1ccccc1 +632,skb-i,0,c1cc2c(C(N[C@@H](CC)c3ccccc3)=O)c(c(nc2cc1)c1ccccc1)Cn1cncc1 +633,sparfloxacin,0,C[C@H]1CN(C[C@@H](C)N1)c2c(F)c(N)c3C(=O)C(=CN(C4CC4)c3c2F)C(O)=O +634,ethosuximide,1,CCC1(C)CC(=O)NC1=O +635,etymemazine,1,CCc1ccc2Sc3ccccc3N(CC(C)CN(C)C)c2c1 +636,flupentixol,1,OCCN1CCN(CC\C=C/2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 +637,fluphenazine,1,OCCN1CCN(CCCN2c3ccccc3Sc4ccc(cc24)C(F)(F)F)CC1 +638,flurazepam,1,CCN(CC)CCN1C(=O)CN=C(c2ccccc2F)c3cc(Cl)ccc13 +639,glaziovine,1,COc1cc2CCN(C)C3CC4(C=CC(=O)C=C4)c(c1O)c23 +640,glutethimide,1,CCC1(CCC(=O)NC1=O)c2ccccc2 +641,haloperidol,1,OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c3ccc(Cl)cc3 +642,harmalol,1,CC1=C2NC3=CC(=O)C=CC3=C2C=CN1 +643,harman,1,Cc1nccc2c1[nH]c3ccccc23 +644,12,0,c1c(c(ncc1)CSCCN\C(=[NH]\C#N)NCC)Br +645,14,1,c1cc(ncc1)CSCCNc1c(cc[nH]1)[N+](=O)[O-] +646,15,1,c1(cc(nc(c1C)C)C(SC(CNc1c(cc[nH]1)[N+](=O)[O-])(C)C)(C)C)C +647,16,1,n1c(csc1\[NH]=C(\N)N)c1ccccc1 +648,17,0,n1c(csc1\[NH]=C(\N)N)c1cccc(c1)N +649,18,0,n1c(csc1\[NH]=C(\N)N)c1cccc(c1)NC(C)=O +650,19,0,n1c(csc1\[NH]=C(\N)N)c1cccc(c1)N\C(NC)=[NH]\C#N +651,2,1,s1cc(nc1\[NH]=C(\N)N)C +652,22,1,c1(c(oc(c1C)C(N(C(C)(N)C)C(N)(C)C)(C)C)C)C.C[NH+]O.[OH-] +653,23,1,[NH]C(CC(C)C([N@@](C(C)(C)C)C(N)(C)N)(C)C)c1c(c(c[nH+][o+]1)C)[O-] +654,tamitinol,1,CCNCc1c(O)c(C)ncc1CSC +655,tenoxicam,0,CN1C(=C(\O)Nc2ccccn2)/C(=O)c3sccc3[S]1(=O)=O +656,terfenadine,0,CC(C)(C)c1ccc(cc1)C(O)CCCN2CCC(CC2)C(O)(c3ccccc3)c4ccccc4 +657,U50488,1,CN(C1CCCC[C@H]1N2CCCC2)C(=O)Cc3ccc(Cl)c(Cl)c3 +658,heroin,1,CN1CC[C@]23[C@H]4Oc5c(OC(C)=O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4OC(C)=O)c35 +659,hexapropymate,1,NC(=O)OC1(CCCCC1)CC#C +660,homophenazine,1,[H+].[H+].[Cl-].[Cl-].OCCN1CCCN(CCCN2c3ccccc3Sc4cc(ccc24)C(F)(F)F)CC1 +661,hydrocodone,1,COc1ccc2C[C@@H]3[C@@H]4CCC(=O)[C@@H]5Oc1c2[C@]45CCN3C +662,hydroxyphenamate,1,CCC(O)(COC(N)=O)c1ccccc1 +663,hydroxyzine,1,OCCOCCN1CCN(CC1)C(c2ccccc2)c3ccc(Cl)cc3 +664,imipramine,1,CN(C)CCCN1c2ccccc2CCc3ccccc13 +665,ketamine,1,CNC1(CCCCC1=O)c2ccccc2Cl +666,kynurenic acid,1,OC(=O)C1=CC(=O)c2ccccc2N1 +667,24,1,C1CN(CCC1)Cc1cccc(c1)OCCCNC(=O)C +668,25,1,C1CN(CCC1)Cc1cccc(c1)OCCCNC(=O)c1ccccc1 +669,26,1,C1CN(CCC1)Cc1cccc(c1)OCCCO +670,27,1,C1CN(CCC1)Cc1cccc(c1)OCCCNc1ncccc1 +671,28,1,C1CN(CCC1)Cc1cccc(c1)OCCCNc1nccs1 +672,30,1,C1CN(CCC1)Cc1cccc(c1)OCCCNc1nc2c(o1)cccc2 +673,4,0,c1c(oc(c1)CN(C)C)CSCCNc1nc(c(c[nH]1)Cc1cc2c(cc1)cccc2)=O +674,8-5,0,CN(C)Cc1oc(cc1)CSCCNC=1NC=C(CN1)Cc1cnc(cc1)C +675,BBcpd10,0,c1(nccc(c1)c1nc([nH]n1)N)N(C)C +676,9-C1,1,n1(c(c2nc[nH]c2n(c1=O)C)=O)C +677,lenperone,1,Fc1ccc(cc1)C(=O)CCCN2CCC(CC2)C(=O)c3ccc(F)cc3 +678,levorphanol,1,CN1CC[C@]23CCCC[C@H]2[C@H]1Cc4ccc(O)cc34 +679,lidocaine,1,CCN(CC)CC(=O)Nc1c(C)cccc1C 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numnamep_npsmiles
01Propanolol1[Cl].CC(C)NCC(O)COc1cccc2ccccc12
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numnamep_npsmiles
01Propanolol1[Cl].CC(C)NCC(O)COc1cccc2ccccc12
12Terbutylchlorambucil1C(=O)(OC(C)(C)C)CCCc1ccc(cc1)N(CCCl)CCCl
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numnamep_npsmiles
01Propanolol1[Cl].CC(C)NCC(O)COc1cccc2ccccc12
12Terbutylchlorambucil1C(=O)(OC(C)(C)C)CCCc1ccc(cc1)N(CCCl)CCCl
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"[2050 rows x 4 columns]" + ] + }, + "execution_count": 2, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "df= pd.read_csv('BBBP.csv')\n", + "df" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [], + "source": [ + "import numpy as np\n", + "np.savetxt(r'bbbp.txt', df.smiles.values, fmt='%s')" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": {}, + "outputs": [], + "source": [] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.9.5" + }, + "orig_nbformat": 4, + "vscode": { + "interpreter": { + "hash": "a4329ea539b1232b51730207fd9c93849c82cf9ff2a2d6356a1e6b85d15167f8" + } + } + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/Experiments/BBBP/bbbp.txt b/Experiments/BBBP/bbbp.txt new file mode 100644 index 0000000000000000000000000000000000000000..af1c8abdfa31f8fa1fee079e0462bd55c326c669 --- /dev/null +++ b/Experiments/BBBP/bbbp.txt @@ -0,0 +1,1567 @@ +[Cl].CC(C)NCC(O)COc1cccc2ccccc12 +C(=O)(OC(C)(C)C)CCCc1ccc(cc1)N(CCCl)CCCl +c12c3c(N4CCN(C)CC4)c(F)cc1c(c(C(O)=O)cn2C(C)CO3)=O +C1CCN(CC1)Cc1cccc(c1)OCCCNC(=O)C +Cc1onc(c2ccccc2Cl)c1C(=O)N[C@H]3[C@H]4SC(C)(C)[C@@H](N4C3=O)C(O)=O +CCN1CCN(C(=O)N[C@@H](C(=O)N[C@H]2[C@H]3SCC(=C(N3C2=O)C(O)=O)CSc4nnnn4C)c5ccc(O)cc5)C(=O)C1=O +CN(C)[C@H]1[C@@H]2C[C@H]3C(=C(O)c4c(O)cccc4[C@@]3(C)O)C(=O)[C@]2(O)C(=O)\C(=C(/O)NCN5CCCC5)C1=O +Cn1c2CCC(Cn3ccnc3C)C(=O)c2c4ccccc14 +COc1ccc(cc1)[C@@H]2Sc3ccccc3N(CCN(C)C)C(=O)[C@@H]2OC(C)=O +NC(N)=NC(=O)c1nc(Cl)c(N)nc1N +CC1=CN([C@H]2C[C@H](F)[C@@H](CO)O2)C(=O)NC1=O +C(Cl)Cl +C1N(C(CC2CCCCC12)C(NC(C)(C)C)=O)CC(C(Cc1ccccc1)NC(C(NC(c1nc2c(cccc2)cc1)=O)CC(N)=O)=O)O 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+[N+](=NCC(=O)N[C@@H]([C@H](O)C1=CC=C([N+]([O-])=O)C=C1)CO)=[N-] diff --git a/Experiments/BBBP/outputs/FSR/bbbp probab.ipynb b/Experiments/BBBP/outputs/FSR/bbbp probab.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..129d42a833d50962166d33d179aa63978ec3b30e --- /dev/null +++ b/Experiments/BBBP/outputs/FSR/bbbp probab.ipynb @@ -0,0 +1,92 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [], + "source": [ + "import pandas as pd" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [], + "source": [ + "df = pd.read_csv('bbbp_probab.csv')" + ] + }, + { + "cell_type": "code", + "execution_count": 6, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "(array([ 1., 0., 0., 1., 0., 0., 1., 1., 13., 3., 5., 4., 7.,\n", + " 3., 22., 13., 14., 4., 5., 3.]),\n", + " array([0.50096005, 0.5194553 , 0.53795054, 0.55644578, 0.57494103,\n", + " 0.59343627, 0.61193151, 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+CC(C)(O)C(O)c1ccc(O)cc1 +CCC +Cc1cc(O)ccc1C=C1[C]2CN(C)C2CC1=O +CCNc1cccc(C)c1C=Cc1ccccc1 +CC(=O)c1cncn1CC1CCCCC1 +CCCC(C)C1(C)C(=O)NC(=O)NC1=O +CCN(CC)C(=O)C1CCn2cnc1c2C(C)C +CC(C)C +C=C +NCCc1ccccc1 +CNCCc1ccccn1 +CN(C)CCON1c2ccccc2C=Cc2ccccc21 +CN1C(=O)CC(c2ccccc2)C1=O +NC1=NC(=O)C1N(C(=O)C1=CC1)c1ccccc1 +Cc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2C +NC(=O)NO +NC(=O)Nc1cccc(O)c1O +CN1C(=O)CCC1Cc1ccccc1 +Cc1ccc2[nH]c(=O)nc(-c3ccccc3)c2c1 +CCN1c2ccccc2Sc2ccccc21 +CC(=C1CCC(=O)NC1=O)c1ccccc1 +COc1ccc2c(c1)N(CC(C)CN(C)C)c1ccccc1S2 +CCOC(=O)Oc1ccccc1C(C)C +C=C +CCCC(=O)C(=O)n1c2ccccc3sc3ccc(C)cc21 +NC1OCC(c2ccccc2)=NC1=O +CCC +CC1CC(CNC(=O)c2cc(S(C)(=O)=O)ccc2N)N1C +C=C +CCc1ccccc1 +CC1CCCCN1 +O=C(O)Oc1cc2ccccc2s1 +CCC(O)CC1(CC)C(=O)NC(=O)NC1=O +Cc1ccc2c(c1)N(C)CCC(C)C2=O +CC(C)(C)OC(=O)C(C)(C)c1ccccc1 +CN(CCc1ccccc1)CCn1c(=O)[nH]c2ccccc21 +CC(=O)NC(C)NNC(O)c1ccccc1 +NC1CCCCCN1c1ccccc1 +CCCN1CCN(c2cccc(C)c2C)CC1 +C=C(C)OC(=O)O +O=C(O)C1CCN(c2ccccc2)C1 +CN(C)CCC(N)N1c2ccccc2Sc2ccccc21 +C[N+](C)(C)CCO +CCN(CC)CCOC(=O)c1ccc(NC2CCCCC2)cc1 +CCC +NC(N)=O +CC(NN)c1ccccc1 +CN1CCN(CCCCOC2c3ccccc3N(C)c3ccccc32)CC1 +COc1cccc(C(O)(O)OC(C)C)c1 +CN(C)CCC=C1c2ccccc2C(C)(C)c2ccccc21 +CC1OC(c2cccc(Br)c2)CN(C)CCN1C +CCN1N=NNC(=O)C(c2ccccc2)=C1SS +Cc1cccc(C2=NCC(=O)N(C)c3ccc(C)cc32)c1 +Cc1ccc2c(c1)N(CC(C)CN(C)C)c1ccccc1S2 +CCCCCC +COC(=O)C1(c2ccccc2)NNC(=O)NC1=O +CC(C)C +Cc1ccc(CCN(C)C)cc1O +CCN1CCCC1CNC(=O)C1=C(C)C(C(O)N(CC)C(=O)OC(C)(C)O)=C1 +CCOC(CC)CC(N)=O +CNS(=O)(=O)c1ccc2c(c1)N(CCC1CCN(CCOC)CC1)c1ccccc1S2 +CN(C)c1cnccn1 +CCC +CN1CCCC([C]([C]2CCCC2)c2ccccc2)CC1 +CCC(=O)c1ccc(C)cc1 +C=C +CC(=O)C1(O)CCCCC1 +CN(C)c1cnccn1 +Cc1ccc2c(c1)N(CCCN(C)C)c1ccccc1S2 +CN1C(=S)CN=C(c2ccccc2)c2ccccc21 +CN(C)CCC(=O)CCn1c2c(ccccc3ccccc31)S2 +CC(N)C(=O)NNC(Br)c1ccncc1 +CN(C)CCCc1c2c(nc3ccc(O)cc13)N2C +CC(=O)Nc1ccc(C)cc1 +CC(C)C1CCC(=O)OC1(C)C +C=C +Cc1cccc(C)c1OCC1CCCN(C)C1 +C=C +CCCCCCC +Cc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2C +Cc1ccc(C(=O)NCCN2CCN(c3ccccc3)CC2)cc1 +CCn1ccc(=O)c(O)c1C +CCCCCCC +CCCCN1CCC(C(C)=O)CC1 +CCN1C(=O)CN=C(CN2CCN(C)CC2)c2cc(Br)ccc21 +CCOC(=O)c1ccc(O)cc1 +CC(O)Cn1c2ccccc2n1C +CCC1(CC)C(=O)NC(=O)NC1=O +Cc1ccc2c(c1)C(c1ccccc1)=NCC(=S)N2CC(=O)O +Cc1ccc2c(c1)N(CC(C)CN(C)C)c1ccccc1S2 +C1CCCCC1 +NC(N)=Nc1nc(-c2ccccc2)cs1 +Cc1cccc(C)c1NC1=NCC=C1 +CN(C(=O)O)c1cc[nH]c(=O)c1-c1ccccc1 +CN(C)CCc1ccccn1 +Cc1cccc(C(=O)C(=O)N(C)C)c1 diff --git a/Experiments/BBBP/outputs/FSR/bbbp_imp.txt b/Experiments/BBBP/outputs/FSR/bbbp_imp.txt new file mode 100644 index 0000000000000000000000000000000000000000..e991caa6f77cfe446b9ccd495a5a02d4a932221c --- /dev/null +++ b/Experiments/BBBP/outputs/FSR/bbbp_imp.txt @@ -0,0 +1,100 @@ +CC(N)=O +CCNC +O=C1C(=O)C2(CCCC2)N2CCC1CC2 +CC(C)O +CCCl +CC(C)NCC1C2=CC=CC=C1c1ccccc1O2 +CCCCC +C=C(CC)CCNC(Cl)c1ccccc1 +CCO +CC(C)C +C[CH]C(C)CC(CCCCCCC)COC(=O)NC +CCCCCC +CC(C)c1ccc(OCCCN(C)C)cc1 +O=C1CCc2ccccc2C(CCCCO)=NC1 +CN(C)CCNC1c2ccccc2Sc2cccc(Cl)c21 +Nc1ccccc1 +CNC(N)=O +CCC(C)CCN +CCCc1cccc(C)c1 +CN(O)CCCCl +CCOCC +C=C +CC(C)CO +CC(CC1C2=C(C=CC=Cc3ccccc31)S2)N(C)C +ClC(Cl)Br +Clc1ccc2c(c1)C(C1CCNCC1)=NC2 +ClCCl +CCCCCCC +CCO +CCONC(C)=O +CCCl +CC=CCC(SCCO)c1ccccc1 +CCC(=O)NNC(N)=O +CCO +CC(O)Cl +COc1cccc(C)c1C +CC1CCC(c2ccc3c(c2)CC3c2ccccc2)C1 +CCC(=O)OC(O)C(C)c1ccccc1 +CCCl +Cc1cccc(C(NCCCO)NC(C)C)c1 +CC(C)O +CCCCCC1CC(=O)NC(=O)C(CC)C1 +N#CC=CCCN1CCNCC1 +CCOCC +CCC(N)=O +CCCCCCC1CCCCC1 +ClCCl +OC1CCCCC1 +CCN(COc1ccccc1)C1=CC(c2ccccc2)C1=O +CC(C)O +CCC(C)C +CN1CCOc2cccc(c2)C(c2ccccc2)C1 +ClCCl +CCOCCN(CCCCCC(N)C(C)O)N=O +CCC(C)=O +CCCC(=O)OCCO +CC(C)(C)C +CCCCCl +CCCNCC(C)c1ccccc1 +CC1NNCCN1C1=CC=CCCC1 +CC(C)OC(=O)c1ccc(Cl)nc1N +CN(C)CCCOC1c2ccccc2Cc2ccccc21 +CCCCC +CCOCC +CC(C)O +CCCl +CCCCC +CC(C)NC(C)c1ccccc1 +CC(C)(C)CN +CCC(O)NO +COc1cc(C)cc(C(N)=O)c1 +CC(C)C +CCCCCC +CCO +CC(C)O +CCCl +CC(=O)NC(NC(C)c1ccc(C)cc1)C(C)O +CCC +CCC(N)=O +C=CCl +C=C +ClC(Cl)(Cl)Cl +COC(N)=O +CCCC(N)=O +CCCCCCl +CCCCCCCC +CC(C)C +NCCO +OCCCc1ccccc1 +CCC(F)(F)F +OC(F)(F)C(Cl)Cl +CCC(N)=O +CCCCN +CC(N)=Nc1nc(C)cs1 +CC(C)O +OCCCNCCO +CCO +Cc1ccccc1C(O)N(C)C +CN(C)CCCl +NC(N)=O diff --git a/Experiments/BBBP/outputs/FSR/bbbp_probab.csv b/Experiments/BBBP/outputs/FSR/bbbp_probab.csv new file mode 100644 index 0000000000000000000000000000000000000000..22771b67dc31f21411c10afb78a88dc059b1c1cc --- /dev/null +++ b/Experiments/BBBP/outputs/FSR/bbbp_probab.csv @@ -0,0 +1,101 @@ +SMILES,Probability +CC(N)=O,0.7296579480171204 +CCNC,0.730619490146637 +O=C1C(=O)C2(CCCC2)N2CCC1CC2,0.7930776476860046 +CC(C)O,0.6664993762969971 +CCCl,0.8035035729408264 +CC(C)NCC1C2=CC=CC=C1c1ccccc1O2,0.8006647825241089 +CCCCC,0.7700357437133789 +C=C(CC)CCNC(Cl)c1ccccc1,0.8625566363334656 +CCO,0.6506184935569763 +CC(C)C,0.7700357437133789 +C[CH]C(C)CC(CCCCCCC)COC(=O)NC,0.8528176546096802 +CCCCCC,0.7885003685951233 +CC(C)c1ccc(OCCCN(C)C)cc1,0.8366795182228088 +O=C1CCc2ccccc2C(CCCCO)=NC1,0.6943302750587463 +CN(C)CCNC1c2ccccc2Sc2cccc(Cl)c21,0.8010733723640442 +Nc1ccccc1,0.7228365540504456 +CNC(N)=O,0.7177274823188782 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+CC(=O)NC(NC(C)c1ccc(C)cc1)C(C)O,0.6520267724990845 +CCC,0.7700357437133789 +CCC(N)=O,0.7750377058982849 +C=CCl,0.7708366513252258 +C=C,0.7302247285842896 +ClC(Cl)(Cl)Cl,0.7651368975639343 +COC(N)=O,0.7267969846725464 +CCCC(N)=O,0.7750377058982849 +CCCCCCl,0.821830153465271 +CCCCCCCC,0.8128822445869446 +CC(C)C,0.7700357437133789 +NCCO,0.5009600520133972 +OCCCc1ccccc1,0.7062258124351501 +CCC(F)(F)F,0.795904278755188 +OC(F)(F)C(Cl)Cl,0.784778892993927 +CCC(N)=O,0.7750377058982849 +CCCCN,0.6831572651863098 +CC(N)=Nc1nc(C)cs1,0.6887747645378113 +CC(C)O,0.6664993762969971 +OCCCNCCO,0.6277199387550354 +CCO,0.6506184935569763 +Cc1ccccc1C(O)N(C)C,0.7967138290405273 +CN(C)CCCl,0.7917399406433105 +NC(N)=O,0.720016598701477 diff --git a/Experiments/BBBP/outputs/bbbp.png b/Experiments/BBBP/outputs/bbbp.png new file mode 100644 index 0000000000000000000000000000000000000000..75733b6c7f8f6e0c07493c154db0727f0103911d Binary files /dev/null and b/Experiments/BBBP/outputs/bbbp.png differ diff --git a/Experiments/BBBP/outputs/bbbp_gen.txt b/Experiments/BBBP/outputs/bbbp_gen.txt new file mode 100644 index 0000000000000000000000000000000000000000..7008c50f43be06d61b5c80cfbabdef607e63bee7 --- /dev/null +++ b/Experiments/BBBP/outputs/bbbp_gen.txt @@ -0,0 +1,100 @@ +Cc1cccc(Cl)c1 +CCCCC(C)C1c2ccc(Cl)cc21 +CC(C)(C)SCC(=O)O +COC1C=C(C)CCCC1 +COCCC(C)CCC(Cl)c1ccccc1 +CCCCCCCCCCC +O=C(O)Cl +Cc1ccc(O)cc1 +CCCC(O)c1ccc(O)cc1 +CC1(C)C=CC=C2NC(=O)NC(=CCc3ccccc3)C2=C1 +CCCC1CCCN(CCC)CN1 +C1CCCCC1 +CC(C)(C)Cl +CCC(=O)c1cccc(C)c1 +CN(C)CCCc1ccc2c(c1)CCc1ccccc1CO2 +CC(C)Cl +CC(C)CN1c2ccccc2CCc2ccccc21 +NC(O)=NC(=O)N1CCCCC1 +CC1CC=CC(O)C1 +Cc1ccccc1CCN1CCC(c2ccc(F)cc2)CC1 +CC1CCN(C(=O)CC2CCCCN(C)CC2)CC1 +CN1CCCCCN(CCCN2c3ccccc3Sc3ccccc32)CC1 +CN1CCC(=O)N(N(C)C(=O)O)C1=O +OCCN1CCN(CCCC2=NCC3(C=CC=CC3)Sc3ccc(Cl)cc32)CC1 +Clc1ccccc1-c1ccc(CCC2CCCCN2)cc1 +Cc1ccc(C(N)=O)cc1 +CCN1CCN(CCC(=O)c2ccccc2)CCC(c2ccccc2)C1O +C=CC1C(O)CCN(CCCC2c3ccccc3Sc3ccccc32)CCN1CCC +C1=CCCC2CCN(CC2)C(c2ccccc2)C=C1 +Cc1ccc(C(=O)N2CCCC2)cn1 +FCC(F)(F)F +CCCC(O)c1cccc(OC)c1 +CCc1ccc(C(C)CC)cc1 +CC(C)Cl +NNCCSC1c2ccccc2Sc2ccccc21 +FC(F)(Cl)CCCl +CN(C)CCCc1ccc(C2=CCCN2)cc1 +CN1CCN(CCCn2c3c(ccccc4ccccc42)S3)CC1 +CC1CCN(CCCC2C3=C(C=CC=Cc4ccccc42)S3)CC1 +C#CC=CC(C)(C)C +CCC(C)OC(=O)c1cccc(C)c1 +COC(=O)c1ccc(O)cc1 +Oc1ccc(F)cc1O +CCCCCC(C)c1ccc(C(=O)CCC)cc1 +CCC(N)=O +CCN(C)CCOc1ccc(C)c(C)c1 +Clc1ccc(C2CCCN2Cc2cccnc2)cc1 +CCCN(C)C +CC1=CC(=O)CSCCCCC1 +CCC1(C)CCC1 +CCOC(=O)C(=O)c1ccccc1 +CCNCC(=O)c1ccccc1 +CCC(N)=O +FC(F)(Cl)Br +CCC(C)NCC(O)c1ccccc1OC +NC(N)C(=O)c1ccccc1 +CC1CCCCC1=O +CNCCc1ccc2c(c1)CCC2c1ccccc1 +C=C1CCc2ccccccc(n2O)C1 +CN1CCCC(c2ccccc2)C1 +CC(=O)C(CC1(C)CC1=O)c1ccccc1 +CON1C(=O)CC=C1CCNCC(O)C(=O)N1CCCC1 +CN1CCCNC1=O +COC1CN=C(c2ccccc2Cl)c2ncccc2O1 +CN1CCC2CC1C(O)CNC(C(=O)O)O2 +CCCC(C)OC(C)(C)c1ccc(C)cc1 +CC(C)CCC(C)C1CNC(=O)C1C +CC(C)NCCC(O)c1ccc(O)cc1 +NCCCC(CNc1ccccc1)N1CCCC1 +NC=O +CCCCC1CCC1 +CC(C)CCC=CC(=O)c1cncnc1 +CN1CCCC1 +FC(F)C(F)(F)C(F)(F)F +CC(CCCCC1CCCCN1)C1=CCC=CC=C1 +C=C(CCCCCCCC)c1ccccc1 +CCC(C(C)=O)c1cccc(N)c1OC +CCCC1CCCCCC2CCN1C=CC=Cc1ccccc12 +CCc1ccc(C(=O)c2ccc(Cl)cc2)cc1 +C#C +CCSC(c1ccccc1)c1ccccc1 +CCCCOc1ccc(O)cc1 +CCCCCCC +CC(C)(O)c1ccc2c(c1)NCCCCC2 +CC1=CC=CC=NC1(CCCN(C)C)Cc1ccccc1 +CC(C)(C)C +CCCCCCCCCC1C(=O)NC1=O +NC(=O)C(=O)NCCSCC(N)Cc1ccccc1 +COC1=C(C)N(C(c2ccccc2)c2ccc(Cl)cc2)CCCN1 +Cc1ccc(CCNN2CCCC2)c(O)c1 +CC(F)(CF)CCCl +COc1ccc(S)c(O)c1 +[Cl-] +CCCCCl +COC(C)(C)Cl +CC(=O)NC(c1ccccc1)c1ccccc1 +CCC(F)N(C(Cl)(Cl)Cl)C(F)(F)OC(F)F +CCCC(C)C +CCCCCCCCCCCCCCC(C)C +CCCO diff --git a/Experiments/BBBP/running utils/base_config.json b/Experiments/BBBP/running utils/base_config.json new file mode 100644 index 0000000000000000000000000000000000000000..4e3312a802a1796e76ebe4fe6459770cce1aa73d --- /dev/null +++ b/Experiments/BBBP/running utils/base_config.json @@ -0,0 +1,23 @@ +{ + "exp_name": "LSTM_Chem", + "data_filename": "/content/medium.txt", + "data_length": 0, + "units": 300, + "num_epochs": 4, + "optimizer": "adam", + "seed": 71, + "batch_size": 128, + "validation_split": 0.1, + "verbose_training": true, + "checkpoint_monitor": "val_loss", + "checkpoint_mode": "min", + "checkpoint_save_best_only": false, + "checkpoint_save_weights_only": true, + "checkpoint_verbose": 1, + "tensorboard_write_graph": true, + "sampling_temp": 0.8, + "smiles_max_length": 128, + "finetune_epochs": 10, + "finetune_batch_size": 1, + "finetune_data_filename": "/content/bbbp.txt" +} \ No newline at end of file diff --git a/Experiments/BBBP/running utils/functions.csv b/Experiments/BBBP/running utils/functions.csv new file mode 100644 index 0000000000000000000000000000000000000000..6083018652154fe92e56e4909d0ed2e5428e23ae --- /dev/null +++ b/Experiments/BBBP/running utils/functions.csv @@ -0,0 +1,1246 @@ +,Len,Functional grp name,SMARTS,Smiles,Validity +0,7,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +1,8,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O,Valid +2,15,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1,Valid +3,5,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O,Valid +4,8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1,Valid +5,4,Thioesters,[CX3](=[SX1])[SX2],SC=S,Valid +6,13,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl,Valid +7,5,Epoxides,[CX4]1[CX4][OX2]1,C1CO1,Valid +8,12,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +9,13,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC,Valid +10,11,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1,Valid +11,18,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +12,16,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH],Valid +13,18,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1,Valid +14,16,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1,Valid +15,16,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1,Valid +16,14,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH],Valid +17,4,Thiols,[#16X2H1],[SH],Valid +18,7,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH],Valid +19,7,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S,Valid +20,3,Nitroso (general),[NX2]=[OX1],N=O,Valid +21,3,Azo-type (general),[NX2]=[NX2],N=N,Valid +22,5,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O,Valid +23,5,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1,Valid +24,8,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1,Valid +25,4,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N,Valid +26,32,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1,Valid +27,32,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1,Valid +28,11,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O,Valid +29,6,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O,Valid +30,8,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +31,11,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH],Valid +32,7,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +33,5,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O,Valid +34,2,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN,Valid +35,5,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O,Valid +36,6,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC,Valid +37,18,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +38,8,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O,Valid +39,10,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O,Valid +40,11,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O,Valid +41,8,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +42,5,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O,Valid +43,5,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S,Valid +44,18,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +45,7,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl,Valid +46,5,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1,Valid +47,7,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O,Valid +48,10,Primary alkyl amines,[CH2][NH2],[CH2][NH2],Valid +49,18,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3],Valid +50,20,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1,Valid +51,22,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +52,13,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1,Valid +53,19,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21,Valid +54,7,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +55,7,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC,Valid +56,4,Thiocyanates,[SX2][CX2]#[NX1],N#CS,Valid +57,21,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O,Valid +58,12,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +59,6,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O,Valid +60,6,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C,Valid +61,6,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N,Valid +62,12,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C,Valid +63,7,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S,Valid +64,7,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S,Valid +65,2,Peroxides,[OX2][OX2],OO,Valid +66,2,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS,Valid +67,4,Nitroso,[#6][NX2]=[OX1],CN=O,Valid +68,4,N-Nitroso,[#7][NX2]=[OX1],NN=O,Valid +69,5,Azo,[#6][NX2]=[NX2][#6],CN=NC,Valid +70,5,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC,Valid +71,5,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C,Valid +72,6,Hydroxylamines,[OH1][NX3][#6],CN[OH],Valid +73,3,Aminals,N[CX4]N,NCN,Valid +74,12,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C,Valid +75,9,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C,Valid +76,9,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O,Valid +77,9,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O,Valid +78,9,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C,Valid +79,10,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O,Valid +80,6,Acrylonitriles,[NX1]#CC=C,C=CC#N,Valid +81,12,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O,Valid +82,14,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1,Valid +83,5,Ketenes,[CX3]=[CX2]=[OX1],C=C=O,Valid +84,5,Allenes,C=C=C,C=C=C,Valid +85,5,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1,Valid +86,5,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1,Valid +87,5,Aziridines,[CX4]1[NX3][CX4]1,C1CN1,Valid +88,6,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1,Valid +89,6,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1,Valid +90,6,Selen in chain,[Sev2X2],[SeH2],Valid +91,12,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O,Valid +92,12,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N,Valid +93,4,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O,Valid +94,7,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S,Valid +95,7,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S,Valid +96,7,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S,Valid +97,7,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S,Valid +98,11,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O,Valid +99,1,Positively charged N-heterocycles,[#7v4X3R],N,Valid +100,18,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH],Valid +101,20,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1,Valid +102,22,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1,Valid +103,25,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1,Valid +104,27,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1,Valid +105,18,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12,Valid +106,12,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl,Valid +107,12,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O,Valid +108,13,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC,Valid +109,13,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC,Valid +110,9,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O,Valid +111,6,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N,Valid +112,11,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C,Valid +113,10,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O,Valid +114,10,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C,Valid +115,12,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH],Valid +116,12,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C,Valid +117,9,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C,Valid +118,2,Iodine,II,II,Valid +119,8,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H],Valid +120,3,Sulfoxides,[Sv4X3](=[OX1]),O=S,Valid +121,2,Sulfenyl iodides,[SX2][IX1],SI,Valid +122,4,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS,Valid +123,8,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S,Valid +124,8,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS,Valid +125,7,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH],Valid +126,41,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1,Valid +127,5,Organotin compounds,[Sn][#6],C[Sn],Valid +128,8,β-Lactones,C1C(=O)OC1,O=C1CCO1,Valid +129,8,Thio-lactones,C1C(=O)SC1,O=C1CCS1,Valid +130,10,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC,Valid +131,26,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH],Valid +132,14,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1,Valid +133,11,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2],Valid +134,14,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1,Valid +135,11,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1,Valid +136,5,Sulfuranes,C1[SX2]C1,C1CS1,Valid +137,11,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1,Valid +138,12,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O,Valid +139,8,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O,Valid +140,16,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl,Valid +141,17,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C,Valid +142,18,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C,Valid +143,39,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH],Valid +144,19,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH],Valid +145,15,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1,Valid +146,30,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21,Valid +147,11,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O,Valid +148,24,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O,Valid +149,20,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1,Valid +150,7,Furans,c1ccc[oX2]1,c1ccoc1,Valid +151,7,Thiophenes,c1ccc[sX2]1,c1ccsc1,Valid +152,17,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O,Valid +153,10,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH],Valid +154,4,Thioles,[Sv2X2H1],[SH],Valid +155,8,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O,Valid +156,11,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH],Valid +157,1,Phosphorus,P,P,Valid +158,6,Selen,[Se],[SeH2],Valid +159,1,Bor,B,B,Valid +160,6,Silicium,[Si],[SiH4],Valid +161,3,Thione,[CX3]=[SX1!R],C=S,Valid +162,9,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH],Valid +163,7,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S,Valid +164,25,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2],Valid +165,12,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O,Valid +166,16,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1,Valid +167,16,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1,Valid +168,16,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1,Valid +169,16,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1,Valid +170,17,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1,Valid +171,6,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O,Valid +172,6,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N,Valid +173,16,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O,Valid +174,10,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N,Valid +175,12,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S,Valid +176,34,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12,Valid +177,40,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O,Valid +178,16,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH],Valid +179,2,N-N Single bound not in a ring,[N!R][N!R],NN,Valid +180,11,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC,Valid +181,10,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O,Valid +182,12,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1,Valid +183,15,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O,Valid +184,18,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3,Valid +185,18,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3,Valid +186,21,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1,Valid +187,18,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23,Valid +188,6,Cyano carbonyl compounds ,N#CC(=O),N#CC=O,Valid +189,5,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N,Valid +190,6,Benzyl ammoniums,cC[NX4+],cC[N+],Valid +191,8,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O,Valid +192,9,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N,Valid +193,7,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O,Valid +194,3,Singel acyclic N-N bonds,[#7]!@-N,N~N,Valid +195,11,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N,Valid +196,7,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O,Valid +197,2,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS,Valid +198,8,Phosphonates,[#6]P(=O)O[#6],COP(C)=O,Valid +199,16,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +200,14,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O,Valid +201,4,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS,Valid +202,13,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O,Valid +203,11,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F,Valid +204,4,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O,Valid +205,20,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1,Valid +206,15,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1,Valid +207,3,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC,Valid +208,4,Phosphocyanates,PC#N,N#CP,Valid +209,8,α-Hydroxy nitriles,N#CC[OH],N#CC[OH],Valid +210,6,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O,Valid +211,2,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO,Valid +212,11,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N,Valid +213,3,Nitroso compounds,[NX2]=O,N=O,Valid +214,19,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F,Valid +215,22,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +216,17,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1,Valid +217,1,Phosphorus derivatives,[P!v5],P,Valid +218,12,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C,Valid +219,22,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1,Valid +220,18,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1,Valid +221,17,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1,Valid +222,17,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1,Valid +223,7,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O,Valid +224,15,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O,Valid +225,14,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1,Valid +226,6,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC,Valid +227,16,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH],Valid +228,18,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1,Valid +229,20,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21,Valid +230,14,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH],Valid +231,17,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1,Valid +232,15,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21,Valid +233,6,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c,Valid +234,11,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N,Valid +235,6,Phosphorus cations,[#15+],[PH4+],Valid +236,10,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O,Valid +237,3,Double P=O bonds,[#15]=O,O=P,Valid +238,5,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH],Valid +239,7,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +240,3,Nitrosos,[NX2]=[OX1],N=O,Valid +241,10,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F,Valid +242,7,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S,Valid +243,5,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH],Valid +244,12,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH],Valid +245,12,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH],Valid +246,5,Phenols,c[OH1],c[OH],Valid +247,3,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC,Valid +248,3,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc,Valid +249,3,Diarylethers,c[OX2&!$([OX2r3])]c,cOc,Valid +250,6,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid +251,6,Primary aromatic amines,[NX3H2]c,c[NH2],Valid +252,6,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C,Valid +253,6,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C,Valid +254,6,Secondary aromatic amines,[NX3H1](c)c,c[NH]c,Valid +255,6,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C,Valid +256,5,Organolithium compounds,[Li][#6],[Li]C,Valid +257,5,Organomagnesium compounds,[Mg][#6],C[Mg],Valid +258,7,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O,Valid +259,10,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O,Valid +260,7,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O,Valid +261,11,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH],Valid +262,9,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC,Valid +263,10,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH],Valid +264,13,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC,Valid +265,12,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O,Valid +266,11,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O,Valid +267,8,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O,Valid +268,7,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O,Valid +269,6,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH],Valid +270,4,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC,Valid +271,7,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C,Valid +272,5,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH],Valid +273,5,Thiophenols,c[Sv2H1],c[SH],Valid +274,13,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH],Valid +275,13,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH],Valid +276,6,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C,Valid +277,10,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O,Valid +278,12,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH],Valid +279,6,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C,Valid +280,7,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C,Valid +281,7,Alkynyl alcohols,[CX2]#[CX2][OH1],C#C[OH],Valid +282,7,Alkynyl thiols,[CX2]#[CX2][SH1],C#C[SH],Valid +283,21,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O,NC(COP(O)(O)=O)C(O)=O,Valid +284,24,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O,CC(OP(O)(O)=O)C(N)C(O)=O,Valid +285,31,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,Valid +286,10,sulphonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +287,14,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S,O=C(S)C(F)(F)F,Valid +288,5,hydroxamate_warhead,C([N;H1]([O;D1]))=O,ONC=O,Valid +289,12,thiol_warhead,NC(C[S;D1])C(O)=O,NC(CS)C(O)=O,Valid +290,6,acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +291,25,pentafluorophenylester,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +292,10,acyl_imidazole,"[C;!$(C-N)](=O)n1[c;H1,$([#6]([*;!R]))]n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1ccnc1,Valid +293,16,ortho_hydroiminoquinone,c1c([N;D1])c([N;D1])c[cH1][cH1]1,Nc1c[cH][cH]cc1N,Valid +294,3,phosphorus_phosphorus_bond,P~P,P~P,Valid +295,10,acyl_pyrazole,"[C;!$(C-N)](=O)n1n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1cccn1,Valid +296,12,acyl_123_triazole,"[#7;R1]1=,:[#7;R1]-,:[#7;R1](-C(=O))-,:[#6]=,:[#6]1",O=CN1C=CN=N1,Valid +297,7,alpha_dicarbonyl,C(=O)!@C(=O),O=C~C=O,Valid +298,14,trifluoroacetate_ester,C(F)(F)(F)C(=O)O,OC(=O)C(F)(F)F,Valid +299,2,sulf_D2_nitrogen,[S;D2](-[N;!$(N(=C));!$(N(-S(=O)(=O)));!$(N(-C(=O)))]),NS,Valid +300,18,triflate,OS(=O)(=O)(C(F)(F)(F)),OS(=O)(=O)C(F)(F)F,Valid +301,15,rhodanine,C(=C)1SC(=S)NC(=O)1,C=C1SC(=S)NC1=O,Valid +302,5,NO_phosphonate,P(=O)ON,NOP=O,Valid +303,3,azo_filter3,[N;!R]-[N;!R]-[N;!R],NNN,Valid +304,30,disulfonyliminoquinone,S(=O)(=O)N=C1C=CC(=NS(=O)(=O))C=C1,O=S(=O)N=C1C=CC(=NS(=O)=O)C=C1,Valid +305,28,perchloro_cp,C1(Cl)(Cl)C(Cl)C(Cl)=C(Cl)C1(Cl),ClC1C(Cl)=C(Cl)C(Cl)C1(Cl)Cl,Valid +306,20,meldrums_acid_deriv,O=C1OC(C)(C)OC(C1)=O,CC1(C)OC(=O)CC(=O)O1,Valid +307,2,sulf_D2_oxygen_D2,[S;D2][O;D2],OS,Valid +308,3,azo_filter2,[N;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!r3;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!$(N-S(=O)(=O));!$(N-C=O)],NNN,Valid +309,2,hydrazine,[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))]-[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))],NN,Valid +310,10,isonitrile,[N+]#[C-],[C-]#[NH+],Valid +311,14,gte_3_COOH,C(=O)[O;D1].C(=O)[O;D1].C(=O)[O;D1],OC=O.OC=O.OC=O,Valid +312,3,phosphorus_sulfur_bond,P~S,P~S,Valid +313,9,polyene,C=[C;!R][C;!R]=[C;!R][C;!R]=[C;!R],C=CC=CC=C,Valid +314,4,azo_amino,[N]=[N;!R]-[N],N=NN,Valid +315,7,nitrone,[C;!R]=[N+][O;D1],C=[N+]O,Valid +316,1,sulfonium,[S+;X3;$(S-C);!$(S-[O;D1])],S,Valid +317,3,polysulfide,[S;D2]-[S;D2]-[S;D2],SSS,Valid +318,6,acrylate,[CH2]=[C;!$(C-N);!$(C-O)]C(=O),C=CC=O,Valid +319,15,four_nitriles,C#N.C#N.C#N.C#N,C#N.C#N.C#N.C#N,Valid +320,3,phosphorane,C=P,C=P,Valid +321,20,gte_7_aliphatic_OH,C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1],CO.CO.CO.CO.CO.CO.CO,Valid +322,9,gte_2_free_phos,P([O;D1])=O.P([O;D1])=O,OP=O.OP=O,Valid +323,22,benzidine_like,c([N;!+])1ccc(c2ccc([N;!+])cc2)cc1,Nc1ccc(c2ccc(N)cc2)cc1,Valid +324,9,hydrazothiourea,[N;!R]=NC(=S)N,NC(=S)N=N,Valid +325,4,nitrosamine,N-[N;X2](=O),NN=O,Valid +326,10,gte_10_carbon_sb_chain,[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R],CCCCCCCCCC,Valid +327,10,betalactam,C1(=O)~[#6]~[#6]N1,O=C1NC~C~1,Valid +328,3,peroxide,[#8]~[#8],O~O,Valid +329,18,paraquat_like,[#6]1[#6][#6]([#6]2[#6][#6][#7;+][#6][#6]2)[#6][#6][#7;+]1,C1CC(C2CCNCC2)CCN1,Valid +330,5,azo_aryl,c[N;!R;!+]=[N;!R;!+]-c,cN=Nc,Valid +331,2,disulfide_acyclic,[S;!R;X2]-[S;!R;X2],SS,Valid +332,5,gte_3_iodine,[#53].[#53].[#53],I.I.I,Valid +333,17,porphyrin,"[#6;r16,r17,r18]~[#6]1~[#6]~[#6]~[#6](~[#6])~[#7]1",C~C1N~C(~C)~C~C~1,Valid +334,7,thio_xanthate,[S;!R]-[C;!R](=[S;!R])(-[S;!R]),S=C(S)S,Valid +335,13,double_trouble_warhead,NC(C[S;D1])C([N;H1]([O;D1]))=O,NC(CS)C(=O)NO,Valid +336,13,Hzone_phenol_A,c1ccc(c(c1)[#8!H0])[#6]=[#7][#7],NN=Cc1ccccc1O,Valid +337,3,Azo_A,[N!R]=N,N=N,Valid +338,14,Mannich_A,N[CX4]c1c([OH1])cccc1,NCc1ccccc1[OH],Valid +339,15,Ene_rhod_A,N1C(=S)SC(=C)C1=O,C=C1SC(=S)NC1=O,Valid +340,18,Hzone_phenol_B,c1(ccc(cc1)C=N[#7])[OH1],NN=Cc1ccc([OH])cc1,Valid +341,20,Imine_one_isatin,[OX1]=C2C(=;!@N[#7])c3c(cccc3)N2,NN=C1C(=O)Nc2ccccc21,Valid +342,18,Anil_di_alk_B,c1c(ccc(c1)[#6]=[#6])[#7]([CX4])[CX4],CN(C)c1ccc(C=C)cc1,Valid +343,16,Catechol_A,c1ccc(c(c1)[OH1])[OH1],[OH]c1ccccc1[OH],Valid +344,21,Ene_five_one_A,c2ccc1C(=[OX1])C(=C)C(=[OX1])c1c2,C=C1C(=O)c2ccccc2C1=O,Valid +345,12,Ene_five_het_B,C1(=C)C(N=CS1)=O,C=C1SC=NC1=O,Valid +346,15,Ene_five_het_D,C1(=C)C(=[OX1])NNC1=[OX1],C=C1C(=O)NNC1=O,Valid +347,27,Ene_five_het_F,c1(ccccc1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)S2,O=C1C(=Cc2ccccc2)Sc2ccccc21,Valid +348,20,Ene_one_ester,[#6][#6](=[#8])[#6!H0]=[#6]([#7!H0][#6])[#6](=[#8])[#8][#6],CNC(=CC(C)=O)C(=O)OC,Valid +349,18,Ene_one_D,c([OH1])c-C(=[OX1])[C!H0]=C([#6])[#6],CC(C)=CC(=O)cc[OH],Valid +350,19,Ene_cyano_A,[#6](C#[#7])(C#[#7])=Cc1ccccc1,N#CC(=Cc1ccccc1)C#N,Valid +351,21,Hzone_pyrrol,n1(C)[cH1][cH1][cH1]c1C=NN,Cn1[cH][cH][cH]c1C=NN,Valid +352,45,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2,C=NNC(=O)c1[cH]c2[cH][cH][cH][cH]c2[cH]c1[OH],Valid +353,19,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1,O=C1CC(=O)c2ccccc21,Valid +354,22,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1],N#CC=C([NH2])C(C#N)C#N,Valid +355,20,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1,N#CC(C#N)=NNc1ccccc1,Valid +356,20,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9,C1C=CC2C1CNc1ccccc12,Valid +357,21,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7],Nc1c2ccccc2nc2ccccc12,Valid +358,13,Thiophene_hydroxy,"[#16]1-,:[#6]=,:[#6]-,:[#6](=,:[#6]1)[OH1]",[OH]C1=CSC=C1,Valid +359,25,Sulfonamide_B,c1c(ccc(c1)[NH]S(=[OX1])=[OX1])[OH1],O=S(=O)[NH]c1ccc([OH])cc1,Valid +360,7,Thio_ketone,"[#6]-,:[CX3](=[SX1])-,:[#6]",CC(C)=S,Valid +361,13,Rhod_sat_A,"[#7]1-,:[#6](=[#16])-,:[#16]-,:[#6X4]-,:[#6]1=[#8]",O=C1CSC(=S)N1,Valid +362,20,Imine_one_sixes,C1(C(=[OX1])NC(=[OX1])NC1(=[OX1]))=N,N=C1C(=O)NC(=O)NC1=O,Valid +363,22,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1,Valid +364,21,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1,Valid +365,21,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH],Valid +366,34,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +367,46,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH],Valid +368,31,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH],Valid +369,31,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1,Valid +370,51,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1,Valid +371,25,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH],Valid +372,36,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1,Valid +373,14,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1,Valid +374,27,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2,Valid +375,72,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1,Valid +376,39,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12,Valid +377,24,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC,Valid +378,27,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1,Valid +379,40,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1,Valid +380,32,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH],Valid +381,45,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12,Valid +382,38,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1,Valid +383,21,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2],Valid +384,39,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1,Valid +385,27,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12,Valid +386,31,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1,Valid +387,34,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12,Valid +388,52,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1,Valid +389,25,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1,Valid +390,30,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1,Valid +391,18,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1,Valid +392,46,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1,Valid +393,18,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1,Valid +394,22,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1,Valid +395,34,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2,Valid +396,18,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1,Valid +397,46,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +398,39,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1,Valid +399,32,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1,Valid +400,34,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12,Valid +401,17,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1,Valid +402,29,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O,Valid +403,21,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12,Valid +404,29,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21,Valid +405,48,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1,Valid +406,48,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1,Valid +407,22,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1,Valid +408,38,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc,Valid +409,34,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1,Valid +410,45,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1,Valid +411,19,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3,Valid +412,33,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21,Valid +413,22,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21,Valid +414,28,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12,Valid +415,18,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1,Valid +416,14,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1,Valid +417,20,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc,Valid +418,13,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1,Valid +419,26,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1,Valid +420,42,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1,Valid +421,18,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1,Valid +422,41,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21,Valid +423,48,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12,Valid +424,52,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21,Valid +425,10,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1,Valid +426,22,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1,Valid +427,16,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2,Valid +428,19,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc,Valid +429,44,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1,Valid +430,24,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21,Valid +431,26,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2,Valid +432,29,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21,Valid +433,30,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc,Valid +434,33,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21,Valid +435,15,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN,Valid +436,15,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S,Valid +437,12,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N,Valid +438,65,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1,Valid +439,25,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1,Valid +440,12,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S,Valid +441,23,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S,Valid +442,24,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1,Valid +443,47,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1,Valid +444,16,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O,Valid +445,17,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S,Valid +446,15,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1,Valid +447,41,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O,Valid +448,19,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1,Valid +449,31,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N,Valid +450,28,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21,Valid +451,21,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N,Valid +452,39,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2],Valid +453,48,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1,Valid +454,19,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N,Valid +455,27,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N,Valid +456,24,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc,Valid +457,16,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O,Valid +458,14,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O,Valid +459,19,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O,Valid +460,22,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12,Valid +461,23,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc,Valid +462,25,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1,Valid +463,15,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C,Valid +464,15,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1,Valid +465,18,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1,Valid +466,29,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O,Valid +467,33,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1,Valid +468,24,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1,Valid +469,28,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1,Valid +470,10,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1,Valid +471,22,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1,Valid +472,26,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1,Valid +473,25,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1,Valid +474,18,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S,Valid +475,18,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12,Valid +476,44,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1,Valid +477,52,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1,Valid +478,19,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2,Valid +479,22,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1,Valid +480,11,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1,Valid +481,22,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N,Valid +482,20,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12,Valid +483,27,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C,Valid +484,30,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N,Valid +485,28,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1,Valid +486,32,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH],Valid +487,23,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc,Valid +488,33,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12,Valid +489,35,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1,Valid +490,13,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1,Valid +491,20,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O,Valid +492,10,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH],Valid +493,27,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O,Valid +494,20,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21,Valid +495,20,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1,Valid +496,50,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21,Valid +497,42,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21,Valid +498,33,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1,Valid +499,13,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O,Valid +500,22,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O,Valid +501,21,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1,Valid +502,30,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O,Valid +503,11,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C,Valid +504,20,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1,Valid +505,20,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1,Valid +506,16,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21,Valid +507,11,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C,Valid +508,17,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O,Valid +509,15,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH],Valid +510,22,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S,Valid +511,24,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1,Valid +512,34,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1,Valid +513,32,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21,Valid +514,36,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O,Valid +515,24,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1,Valid +516,15,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1,Valid +517,29,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2],Valid +518,40,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1,Valid +519,26,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1,Valid +520,15,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc,Valid +521,25,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1,Valid +522,54,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1,Valid +523,34,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1,Valid +524,22,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc,Valid +525,12,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1,Valid +526,24,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1,Valid +527,24,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O,Valid +528,26,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1,Valid +529,18,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1,Valid +530,46,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1,Valid +531,26,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1,Valid +532,26,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3,Valid +533,25,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1,Valid +534,16,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N,Valid +535,28,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1,Valid +536,36,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O,Valid +537,38,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1,Valid +538,25,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1,Valid +539,38,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1,Valid +540,72,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2,Valid +541,56,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1,Valid +542,40,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1,Valid +543,20,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23,Valid +544,22,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2,Valid +545,35,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F,Valid +546,27,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2,Valid +547,35,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O,Valid +548,21,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1,Valid +549,38,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1,Valid +550,28,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1,Valid +551,32,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O,Valid +552,36,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1,Valid +553,29,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O,Valid +554,32,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O,Valid +555,61,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1,Valid +556,87,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH],Valid +557,27,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH],Valid +558,57,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1,Valid +559,59,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3],Valid +560,49,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1,Valid +561,49,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1,Valid +562,40,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH],Valid +563,23,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH],Valid +564,35,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1,Valid +565,39,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1,Valid +566,25,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1,Valid +567,81,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1,Valid +568,22,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1,Valid +569,31,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH],Valid +570,5,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1,Valid +571,5,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1,Valid +572,5,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1,Valid +573,6,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1,Valid +574,6,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1,Valid +575,6,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1,Valid +576,6,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1,Valid +577,5,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1,Valid +578,5,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1,Valid +579,5,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1,Valid +580,5,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1,Valid +581,6,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1,Valid +582,6,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1,Valid +583,6,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1,Valid +584,6,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1,Valid +585,5,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1,Valid +586,5,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1,Valid +587,5,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1,Valid +588,5,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1,Valid +589,5,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1,Valid +590,5,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1,Valid +591,5,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1,Valid +592,6,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1,Valid +593,6,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1,Valid +594,6,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1,Valid +595,6,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1,Valid +596,6,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1,Valid +597,6,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1,Valid +598,7,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1,Valid +599,7,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1,Valid +600,8,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1,Valid +601,7,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1,Valid +602,7,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1,Valid +603,6,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1,Valid +604,6,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1,Valid +605,6,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1,Valid +606,6,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1,Valid +607,6,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1,Valid +608,6,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1,Valid +609,7,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1,Valid +610,7,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1,Valid +611,7,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1,Valid +612,7,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1,Valid +613,7,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1,Valid +614,8,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1,Valid +615,8,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1,Valid +616,8,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1,Valid +617,8,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1,Valid +618,8,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1,Valid +619,8,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1,Valid +620,8,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1,Valid +621,7,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1,Valid +622,7,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1,Valid +623,7,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1,Valid +624,13,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1,Valid +625,13,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1,Valid +626,13,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1,Valid +627,7,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1,Valid +628,7,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1,Valid +629,7,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1,Valid +630,7,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1,Valid +631,7,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1,Valid +632,7,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1,Valid +633,8,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1,Valid +634,8,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1,Valid +635,8,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1,Valid +636,8,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1,Valid +637,8,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1,Valid +638,8,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1,Valid +639,8,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1,Valid +640,8,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1,Valid +641,8,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1,Valid +642,7,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1,Valid +643,7,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1,Valid +644,7,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1,Valid +645,7,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1,Valid +646,7,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1,Valid +647,7,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1,Valid +648,7,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1,Valid +649,7,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1,Valid +650,7,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1,Valid +651,7,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1,Valid +652,7,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1,Valid +653,7,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1,Valid +654,8,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1,Valid +655,8,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1,Valid +656,7,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1,Valid +657,7,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1,Valid +658,7,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1,Valid +659,7,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1,Valid +660,7,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1,Valid +661,7,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1,Valid +662,7,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1,Valid +663,7,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1,Valid +664,7,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1,Valid +665,7,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1,Valid +666,7,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1,Valid +667,7,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1,Valid +668,7,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1,Valid +669,7,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1,Valid +670,7,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1,Valid +671,7,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1,Valid +672,7,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1,Valid +673,7,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1,Valid +674,8,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1,Valid +675,8,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1,Valid +676,8,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1,Valid +677,9,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1,Valid +678,9,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1,Valid +679,8,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1,Valid +680,8,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1,Valid +681,8,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1,Valid +682,8,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1,Valid +683,8,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1,Valid +684,8,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1,Valid +685,8,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1,Valid +686,8,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1,Valid +687,8,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1,Valid +688,5,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C,Valid +689,5,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF,Valid +690,6,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl,Valid +691,6,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr,Valid +692,5,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI,Valid +693,4,Vinyl fluorides,F[CX3]=[CX3],C=CF,Valid +694,5,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl,Valid +695,5,Vinyl bromides,Br[CX3]=[CX3],C=CBr,Valid +696,4,Vinyl iodides,I[CX3]=[CX3],C=CI,Valid +697,4,Alkynyl fluorides,F[CX2]#[CX2],C#CF,Valid +698,5,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl,Valid +699,4,Alkynyl iodides,I[CX2]#[CX2],C#CI,Valid +700,5,Alkynyl bromides,Br[CX2]#[CX2],C#CBr,Valid +701,3,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC,Valid +702,3,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc,Valid +703,3,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc,Valid +704,10,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH],Valid +705,10,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH],Valid +706,5,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C,Valid +707,5,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C,Valid +708,7,Aldehyde,[CX3H1](=O)[#6],C[CH]=O,Valid +709,3,Formaldehyde,[CX3H2](=O),C=O,Valid +710,7,Ketone,[C][C](=O)[C],CC(C)=O,Valid +711,3,Nitrile,[C]#[N],C#N,Valid +712,27,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1,Valid +713,42,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1,Valid +714,19,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21,Valid +715,17,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21,Valid +716,14,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1,Valid +717,10,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1,Valid +718,14,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n,Valid +719,21,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12,Valid +720,21,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1,Valid +721,16,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1,Valid +722,10,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn,Valid +723,17,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1,Valid +724,18,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1,Valid +725,18,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12,Valid +726,18,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12,Valid +727,23,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12,Valid +728,26,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1,Valid +729,18,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1,Valid +730,18,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1,Valid +731,26,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1,Valid +732,18,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1,Valid +733,25,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1,Valid +734,21,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1,Valid +735,21,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12,Valid +736,18,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12,Valid +737,16,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH],Valid +738,16,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S,Valid +739,16,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH],Valid +740,16,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH],Valid +741,16,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S,Valid +742,22,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C,Valid +743,16,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH],Valid +744,22,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C,Valid +745,23,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S,Valid +746,19,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S,Valid +747,21,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH],Valid +748,22,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH],Valid +749,14,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH],Valid +750,11,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH],Valid +751,19,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1,Valid +752,16,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1,Valid +753,24,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1,Valid +754,21,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1,Valid +755,20,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1,Valid +756,11,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1,Valid +757,27,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21,Valid +758,30,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1,Valid +759,22,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12,Valid +760,16,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH],Valid +761,18,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH],Valid +762,22,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH],Valid +763,22,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH],Valid +764,28,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH],Valid +765,27,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH],Valid +766,25,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1,Valid +767,25,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1,Valid +768,29,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1,Valid +769,25,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1,Valid +770,13,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O,Valid +771,4,Pt,[Pt],[Pt],Valid +772,7,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +773,9,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O,Valid +774,34,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +775,28,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1,Valid +776,51,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1,Valid +777,46,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +778,33,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1,Valid +779,36,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21,Valid +780,11,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1,Valid +781,32,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12,Valid +782,35,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1,Valid +783,18,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH],Valid +784,21,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1,Valid +785,32,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1,Valid +786,19,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12,Valid +787,1,Radical,[#16;X3v3+0],S,Valid +788,4,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +789,9,6 - Methanol,[CX4H3][OX2H1],[CH3][OH],Valid +790,1,7 - Water,[OX2H2],O,Valid +791,7,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O,Valid +792,8,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +793,13,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +794,5,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S,Valid +795,15,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +796,18,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +797,1,32 - Iodo compounds,[I],I,Valid +798,2,33 - Bromo compounds,[Br!$([Br][cR])],Br,Valid +799,15,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +800,9,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +801,5,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl,Valid +802,8,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +803,26,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +804,27,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +805,7,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +806,6,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C,Valid +807,9,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH],Valid +808,3,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C,Valid +809,6,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C,Valid +810,3,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C,Valid +811,5,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c,Valid +812,4,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +813,9,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH],Valid +814,1,17 - H2O (7 - Water),[OX2H2],O,Valid +815,11,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O,Valid +816,11,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O,Valid +817,7,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O,Valid +818,12,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O,Valid +819,12,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O,Valid +820,8,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +821,7,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3],Valid +822,7,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2],Valid +823,10,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2],Valid +824,10,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2],Valid +825,9,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2],Valid +826,10,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3],Valid +827,10,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2],Valid +828,9,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH],Valid +829,10,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3],Valid +830,10,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2],Valid +831,23,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1,Valid +832,8,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N,Valid +833,8,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N,Valid +834,7,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH],Valid +835,10,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH],Valid +836,7,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl,Valid +837,9,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl,Valid +838,12,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl,Valid +839,13,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +840,5,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S,Valid +841,9,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH],Valid +842,9,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH],Valid +843,15,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +844,18,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +845,1,64 - I (32 - Iodo compounds),[I],I,Valid +846,2,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br,Valid +847,3,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C,Valid +848,3,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C,Valid +849,15,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +850,9,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +851,5,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl,Valid +852,19,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O,Valid +853,19,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O,Valid +854,8,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +855,6,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3],Valid +856,7,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2],Valid +857,6,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH],Valid +858,5,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si],Valid +859,26,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +860,12,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl,Valid +861,11,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl,Valid +862,10,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl,Valid +863,10,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl,Valid +864,11,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl,Valid +865,8,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O,Valid +866,12,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O,Valid +867,12,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O,Valid +868,16,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O,Valid +869,16,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O,Valid +870,16,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O,Valid +871,15,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH],Valid +872,27,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +873,21,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1,Valid +874,19,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O,Valid +875,18,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O,Valid +876,13,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1,Valid +877,12,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1,Valid +878,9,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1,Valid +879,11,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1,Valid +880,8,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1,Valid +881,5,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1,Valid +882,7,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +883,10,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O,Valid +884,11,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C,Valid +885,35,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1,Valid +886,11,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1,Valid +887,18,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1,Valid +888,14,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O,Valid +889,7,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O,Valid +890,2,R7 - Peroxides,OO,OO,Valid +891,25,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +892,21,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1,Valid +893,7,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O,Valid +894,18,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +895,7,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S,Valid +896,10,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +897,12,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-],Valid +898,5,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O,Valid +899,3,R19 - Phosphoranes,C=P,C=P,Valid +900,8,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +901,3,R21 - Nitroso,[N&D2](=O),N=O,Valid +902,5,R23 - Carbodiumide,N=C=N,N=C=N,Valid +903,10,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +904,13,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +905,8,R26 - Cyanohydrins,N#CC[OH],N#CC[OH],Valid +906,6,R27 - Acyl cyanides,N#CC(=O),N#CC=O,Valid +907,10,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O,Valid +908,16,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +909,6,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N,Valid +910,7,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +911,7,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC,Valid +912,7,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +913,2,I4 - Disulphides,SS,SS,Valid +914,4,I5 - Thiols,[SH],[SH],Valid +915,17,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +916,18,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +917,9,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +918,4,I10 - Thiocyanate,SC#N,N#CS,Valid +919,6,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+],Valid +920,9,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N,Valid +921,8,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1,Valid +922,19,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +923,8,I16 - Betalactams,N1CCC1=O,O=C1CCN1,Valid +924,16,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1,Valid +925,12,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +926,25,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +927,15,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +928,14,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +929,17,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +930,55,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1,Valid +931,14,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +932,13,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1,Valid +933,13,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1,Valid +934,20,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1,Valid +935,17,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O,Valid +936,12,A8,[nH1]1ncoc1=O,O=c1[nH]nco1,Valid +937,13,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1,Valid +938,15,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1,Valid +939,16,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1,Valid +940,13,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1,Valid +941,12,A13,[nH1]1occc1=O,O=c1cco[nH]1,Valid +942,11,A14,[OH1]c1oncc1,[OH]c1ccno1,Valid +943,12,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1,Valid +944,7,A16 - tetrazole,[nH1]nnn,nnn[nH],Valid +945,7,A17,[nH1](n)nn,nn[nH]n,Valid +946,16,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1,Valid +947,16,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1,Valid +948,18,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1,Valid +949,18,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1,Valid +950,16,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1,Valid +951,16,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1,Valid +952,16,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1,Valid +953,26,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21,Valid +954,26,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21,Valid +955,22,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21,Valid +956,16,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH],Valid +957,13,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1,Valid +958,8,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH],Valid +959,21,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F,Valid +960,12,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O,Valid +961,6,B1 - primary amine,[NH2][CX4],C[NH2],Valid +962,6,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C,Valid +963,6,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C,Valid +964,8,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1,Valid +965,7,E4EXC,C(=O)[OH1],O=C[OH],Valid +966,7,E5EXC,C(=O)[SH1],O=C[SH],Valid +967,5,E9EXC,P[OH1],[OH]P,Valid +968,9,E11,c(=O)(~c)~c,c~c(~c)=O,Valid +969,7,E13 - imides,C(=O)-N-C=O,O=CNC=O,Valid +970,6,N1 - pimary amines,[NX3H2][CX4],C[NH2],Valid +971,6,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C,Valid +972,7,N7EXC,[OH1]C=C,C=C[OH],Valid +973,4,Acyclic C=C-O,C=[C!r]O,C=CO,Valid +974,6,Acyl cyanide,N#CC(=O),N#CC=O,Valid +975,9,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O,Valid +976,13,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1,Valid +977,33,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1,Valid +978,11,Azido group,N=[N+]=[N-],[N-]=[N+]=N,Valid +979,3,Azo group,N=N,N=N,Valid +980,38,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1,Valid +981,14,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +982,6,Conjugated nitrile group,C=[C!r]C#N,C=CC#N,Valid +983,16,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1,Valid +984,9,Cyanamide,N[CH2]C#N,N[CH2]C#N,Valid +985,8,Cyanohydrins,N#CC[OH],N#CC[OH],Valid +986,9,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1,Valid +987,9,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1,Valid +988,10,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1,Valid +989,10,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1,Valid +990,3,Diazo group,[N!R]=[N!R],N=N,Valid +991,2,Disulphide,SS,SS,Valid +992,2,Enamine,[CX3R0][NX3R0],CN,Valid +993,7,Ester of HOBT,C(=O)Onnn,nnnOC=O,Valid +994,8,Four member lactones,C1(=O)OCC1,O=C1CCO1,Valid +995,13,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1,Valid +996,8,Hydroxamic acid,C(=O)N[OH],O=CN[OH],Valid +997,3,Imine,C=[N!R],C=N,Valid +998,5,Ketene,C=C=O,C=C=O,Valid +999,10,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1,Valid +1000,11,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O,Valid +1001,14,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1,Valid +1002,5,N-hydroxylpyridine,n[OH],n[OH],Valid +1003,4,N-nitroso,[#7]-N=O,NN=O,Valid +1004,10,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F,Valid +1005,2,Peroxide,OO,OO,Valid +1006,15,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1,Valid +1007,15,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1,Valid +1008,1,Phosphor,P,P,Valid +1009,6,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C,Valid +1010,25,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1011,21,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1,Valid +1012,10,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1013,2,Sulfur oxygen single bond,[SX2]O,OS,Valid +1014,14,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-],Valid +1015,2,Sulphur nitrogen single bond,[SX2H0][N],NS,Valid +1016,15,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1,Valid +1017,15,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1,Valid +1018,5,Thiol (1),[S-],[SH-],Valid +1019,4,Thiol (2),[SH],[SH],Valid +1020,18,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +1021,3,Triple bond,C#C,C#C,Valid +1022,5,Deuterium,[2H],[2HH],Valid +1023,7,C13,[13#6],[13CH4],Valid +1024,10,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1,Valid +1025,23,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O,Valid +1026,2,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN,Valid +1027,3,Acyclic N-C-N,N-!@[CX4]-!@N,NCN,Valid +1028,6,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O,Valid +1029,27,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O,Valid +1030,20,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1,Valid +1031,7,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O,Valid +1032,9,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N,Valid +1033,7,26,N-C(=S)-N,NC(N)=S,Valid +1034,4,Thio cyanates,S-C#N,N#CS,Valid +1035,11,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O,Valid +1036,12,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2],Valid +1037,30,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2],Valid +1038,3,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N,Valid +1039,2,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO,Valid +1040,2,42,S-S,SS,Valid +1041,3,43,O~O,O~O,Valid +1042,18,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3,Valid +1043,7,Too many cyano groups (>1),C#N.C#N,C#N.C#N,Valid +1044,15,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH],Valid +1045,12,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O,Valid +1046,4,Chlorates,Cl~O,O~Cl,Valid +1047,5,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O,Valid +1048,6,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C,Valid +1049,2,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN,Valid +1050,8,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH],Valid +1051,14,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O,Valid +1052,50,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3],Valid +1053,2,Filter35_PP_bond,P-P,PP,Valid +1054,3,Filter36_SS_double_bond,S=S,S=S,Valid +1055,8,Filter37_silicate,[Si]~O,O~[SiH4],Valid +1056,6,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O,Valid +1057,6,Filter51_PN3,N[PX3](N)N,NP(N)N,Valid +1058,16,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +1059,2,Filter56_SS_bond,S-S,SS,Valid +1060,15,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1,Valid +1061,15,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1,Valid +1062,3,Filter59_phoshorous_ylide,C=P,C=P,Valid +1063,3,Filter60_Acyclic_N-S,N!@[SX2],N~S,Valid +1064,24,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F,Valid +1065,14,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH],Valid +1066,7,Filter73_thio_ketone,CC(=S)C,CC(C)=S,Valid +1067,7,Filter76_S_ester,CC(=S)O,CC(O)=S,Valid +1068,20,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1,Valid +1069,4,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N,Valid +1070,3,Filter90_N_double_bond_S,N=!@S,N=S,Valid +1071,12,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O,Valid +1072,7,Anhydride,C(=O)OC(=O),O=COC=O,Valid +1073,26,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1,Valid +1074,7,HOBT ester,C(=O)Onnn,nnnOC=O,Valid +1075,12,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-],Valid +1076,6,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N,Valid +1077,8,Cyanohydrin,N#CC[OH],N#CC[OH],Valid +1078,8,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +1079,13,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +1080,6,Benzylic quaternary nitrogen,cC[N+],cC[N+],Valid +1081,3,Phosphorane,C=P,C=P,Valid +1082,7,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S,Valid +1083,16,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +1084,4,Thiol,[SH],[SH],Valid +1085,20,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1,Valid +1086,18,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +1087,17,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1088,18,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1089,7,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1090,9,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +1091,13,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH],Valid +1092,8,Ester,[#6]-C(=O)O-[#6],COC(C)=O,Valid +1093,3,Imine 3,C=[NH],C=N,Valid +1094,7,Thioketone,CC(=S)C,CC(C)=S,Valid +1095,8,Thionoester,COC(=S)C,COC(C)=S,Valid +1096,7,Thioamide,CC(=S)N,CC(N)=S,Valid +1097,6,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC,Valid +1098,10,Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +1099,4,Thiocyanate,SC#N,N#CS,Valid +1100,21,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1,Valid +1101,6,Dye 2,OCccCO,OCccCO,Valid +1102,2,Disulfide,SS,SS,Valid +1103,11,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N,Valid +1104,6,Oxalyl,O=C-&!@C=O,O=CC=O,Valid +1105,15,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-],Valid +1106,19,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1107,10,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O,Valid +1108,18,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12,Valid +1109,26,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21,Valid +1110,28,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O,Valid +1111,8,Propiolactone,C1(=O)OCC1,O=C1CCO1,Valid +1112,8,b-Lactam,N1CCC1=O,O=C1CCN1,Valid +1113,14,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +1114,25,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1115,17,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +1116,14,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +1117,57,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1,Valid +1118,15,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +1119,28,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1,Valid +1120,17,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1121,18,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1122,7,Acid_anhydrides,C(=O)OC(=O),O=COC=O,Valid +1123,20,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1,Valid +1124,6,Acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +1125,19,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F,Valid +1126,12,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C,Valid +1127,28,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O,Valid +1128,4,Aminonitrile,NC#N,NC#N,Valid +1129,13,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-],Valid +1130,7,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1131,21,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1,Valid +1132,14,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +1133,14,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1,Valid +1134,17,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1,Valid +1135,20,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1,Valid +1136,7,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +1137,19,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1138,6,Diacetylene,C#CC#C,C#CC#C,Valid +1139,11,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-],Valid +1140,7,Diazonium_salt,[N+]#N,N#[NH+],Valid +1141,15,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O,Valid +1142,7,Dithiocarbamate,NC(=S)S,NC(S)=S,Valid +1143,10,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1,Valid +1144,10,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1,Valid +1145,3,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS,Valid +1146,6,Enyne,C=!@CC#C,C#CC=C,Valid +1147,7,Ester_of_HOBT,C(=O)Onnn,nnnOC=O,Valid +1148,30,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2,Valid +1149,8,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF,Valid +1150,10,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F,Valid +1151,8,Four_member_lactones,C1(=O)OCC1,O=C1CCO1,Valid +1152,3,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN,Valid +1153,7,Geminal_dinitriles,N#CCC#N,N#CCC#N,Valid +1154,14,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1,Valid +1155,7,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S,Valid +1156,4,Nitrosamine,N-[N;X2](=O),NN=O,Valid +1157,8,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-],Valid +1158,3,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN,Valid +1159,9,Orthoester,C(O)(O)[OH],OC(O)[OH],Valid +1160,20,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH],Valid +1161,13,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1,Valid +1162,3,PCP,PCP,PCP,Valid +1163,25,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +1164,26,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1165,13,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1,Valid +1166,12,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O,Valid +1167,10,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +1168,12,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +1169,11,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc,Valid +1170,8,Polyines,CC#CC#CC,CC#CC#CC,Valid +1171,20,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1,Valid +1172,22,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12,Valid +1173,26,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1174,11,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1,Valid +1175,3,S=N (not_ring),[S;R0]=[N;R0],N=S,Valid +1176,9,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O,Valid +1177,10,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1178,3,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S,Valid +1179,9,Tetraazinane,C1NNC=NN1,C1NNC=NN1,Valid +1180,14,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S,Valid +1181,15,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1,Valid +1182,29,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1,Valid +1183,32,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1,Valid +1184,17,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O,Valid +1185,11,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O,Valid +1186,14,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1,Valid +1187,3,Thiocarbonyl_group,C=S,C=S,Valid +1188,3,Enamine_like,C=[NH],C=N,Valid +1189,14,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F,Valid +1190,4,Triple_bond,[#6]C#[CH],CC#C,Valid +1191,15,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O,Valid +1192,12,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1,Valid +1193,17,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1,Valid +1194,8,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1,Valid +1195,9,Thiazolidinone,O=C1CSCN1,O=C1CSCN1,Valid +1196,14,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1,Valid +1197,12,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1,Valid +1198,15,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1,Valid +1199,3,Ethene,C=[CH2],C=C,Valid +1200,7,Cyclobutene,C1CC=C1,C1CC=C1,Valid +1201,1,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C,Valid +1202,17,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-],Valid +1203,21,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-],Valid +1204,4,Sulphur atom (1),[SX2H1],[SH],Valid +1205,1,Sulphur atom (6),[sX2r5],s,Valid +1206,1,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C,Valid +1207,1,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C,Valid +1208,1,Nitrogen atoms (7),[nr5H0],n,Valid +1209,27,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21,Valid +1210,16,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C,Valid +1211,25,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1,Valid +1212,24,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1,Valid +1213,31,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1,Valid +1214,25,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1,Valid +1215,24,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1,Valid +1216,27,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1,Valid +1217,27,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1,Valid +1218,20,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1,Valid +1219,19,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1,Valid +1220,19,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1,Valid +1221,23,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1,Valid +1222,22,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2,Valid +1223,22,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC,Valid +1224,21,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1,Valid +1225,16,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1,Valid +1226,27,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1227,32,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1228,34,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1,Valid +1229,20,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1,Valid +1230,20,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1,Valid +1231,16,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1,Valid +1232,22,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1,Valid +1233,22,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12,Valid +1234,21,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1,Valid +1235,14,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1,Valid +1236,17,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1,Valid +1237,17,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1,Valid +1238,32,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1,Valid +1239,20,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1,Valid +1240,12,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2,Valid +1241,11,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2,Valid +1242,19,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1,Valid +1243,15,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2,Valid +1244,6,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid diff --git a/Experiments/BBBP/running utils/medium.txt b/Experiments/BBBP/running utils/medium.txt new file mode 100644 index 0000000000000000000000000000000000000000..21b65a9a233c409ecd425a64054237c77538aa21 --- /dev/null +++ b/Experiments/BBBP/running utils/medium.txt @@ -0,0 +1,180652 @@ +O=C1Nc2cc(NC(=O)c3c[nH]cc(-c4ccc(C(F)(F)F)cc4)c3=O)ccc2C1=Cc1ccc[nH]1 +CC(NC(=O)Nc1cc2[nH]nc(N3CC(C(C)(C)O)C3)c2cn1)c1ccccc1 +N=C(N)C1CCCC(NC(=O)CN2CCCCC(NS(=O)(=O)c3ccccc3)C2=O)C1O +CCN1C(C(=O)NC(Cc2ccccc2)C(=O)C(=O)NCCCN2CCCC2=O)Cc2cc3c(cc2S1(=O)=O)OCCO3 +COCC(=O)NC1CCC(CCN2CCC(c3cccc4occc34)CC2)CC1 +O=C(c1cc(-c2ccc3[nH]ncc3c2)on1)N1CCCCC1 +CN(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1cccc(F)c1 +CC1(C)Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 +CCC(C)C(=O)C1CCC2C3CCC4NC(=O)C=CC4(C)C3CCC12C +C=CCc1cnc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)s1 +CC(C)CC(NC(=O)c1ccc(N2CCN(C)CC2)cc1)C(=O)N1CCC2OCC(=O)C21 +CCOc1ccc(-c2cccc(S(=O)(=O)NC(Cc3cccc(C(=N)N)c3)C(=O)N3CCC(CCN)CC3)c2)cc1 +COC(=O)C1OC(SNCc2ccc(S(N)(=O)=O)cc2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCCCCC2)CC1 +CCC(=O)NCC1CCCc2c1c1cc(OC(F)(F)F)ccc1n2C +Cc1ccnc(-c2nc3cc(F)cc(F)c3c(N3CC4(CCOCC4)c4ncc(N5CCOCC5)cc43)c2C)c1 +CC1CN(Cc2cccc(-c3cc(CNC(=O)c4cccc(CN5CCNCC5)c4)ccc3F)c2)CCN1 +O=C(O)C1CCCCC1NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CCCCC(CC)C(=O)OCC1(CO)CC(=Cc2ccccc2C(F)(F)F)C(=O)O1 +COc1cc(C(=O)NC2(C(=O)NC(C)c3ccc(-c4cc(Cl)cc(F)c4-c4nnn(C)n4)cc3F)COC2)on1 +O=S(=O)(c1cccc2ccccc12)n1ccc2c(N3CCNCC3)c(Cl)ccc21 +Cn1c(=O)c2c(nc(OCc3cccc(C(F)(F)F)c3)n2C)n(C)c1=O +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCCCC2)cc1 +COc1ccccc1NC(=O)N1CCN(Cc2ccc(Br)c(Br)c2)CC1 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccccc3CN(C)C)cc21 +COc1ccc(C(=O)NCC(c2ccccc2)N2CCN(CC(O)COc3ccc(Cl)cc3)CC2)cc1 +CCCCC(CC(CCc1ccc(-c2ccc(C=O)cc2)cc1)C(=O)NC(C(=O)NC)C(C)(C)C)C(=O)O +CN1C2CCC1C(c1cnc(Cl)c(-c3ccccc3)c1)C2 +Cc1cc(O)cc(C)c1CC(N)C(=O)NCCc1nc(O)c(CCNC(=O)C(N)Cc2c(C)cc(O)cc2C)nc1C +CC1(c2cc(NC(=O)c3cnc(-c4ncco4)cn3)ccc2F)C=CSC(N)=N1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCN(CC(=O)N(C)C)C4)nc12 +O=C(CCCN1C2CCC1c1c([nH]c3ccccc13)C2)c1cccs1 +N=C(N)Nc1ncc(Cl)c2ccc(-c3cccc(C(=O)O)c3)cc12 +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(OC(C)C(N)=O)ccc3N2)c(O)c2cccnc21 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=Nc1ccccc1C +COC(=O)c1ccc2nc(Nc3c(C)cccc3Cl)c3cncn3c2c1 +Cc1cc(NC(C)C)nc2ccc(NC(=O)COc3ccc(C(F)(F)F)cc3)cc12 +NS(=O)(=O)c1ccc(NC(S)=NC(CCC(=O)O)C(=O)O)cc1 +CC(C)(C)C1(O)CCN(CC2c3ccccc3C=Cc3ccccc32)CC1 +CC(C)C(=O)NC1CC2(O)C3Cc4ccc(O)cc4C2(CCN3CC2CC2)CC1=O +CCOC(=O)c1cncc(-c2cccc(C(C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)c1 +COc1ccc2c(c1)C(c1ccc(Cl)cc1)=NC(CC(=O)Nc1cccs1)c1nnc(C)n1-2 +CC(CNc1ccc(C(=O)O)cc1)NCC(O)c1cccc(Cl)c1 +CN(C)CCNc1ccc2c(=O)n(CCN(C)C)c(=O)n3c4ccccc4c(=O)c1c23 +CC(C)Oc1ccc(-c2cc3ncccc3c(OCC3CNC(=O)C3)n2)cc1 +Nc1ncnc2c1ncn2C1OC(C(=O)NC23CC4CC(C2)C(C4)C3)C(O)C1O +O=C(c1cc(Br)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2)N1CCC1 +NC(=O)C1C2C=CC(C2)C1Nc1nc(Nc2cnn(CC3CCCN3)c2)ncc1Cl +COc1cc(OCc2csc(N3CCN(c4ccccc4)CC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +O=C(O)c1ccc(-c2ccc(Cl)c(OC3OC(CO)C(O)C(O)C3O)c2)cc1 +CC(C)(C)n1ncc2c1C(=O)NC1(CCN(C(=O)c3ccc4n[nH]cc4c3)CC1)C2 +O=C1C(SCCO)=C(SCCO)C(=O)N1c1ccc(-c2ccccc2)cc1 +O=C1C2CCCCN2C(=O)N1CCCCN1CCN(c2ccccc2)CC1 +COc1noc2c(F)c3c(cc12)CC1(C(=O)NC(=O)NC1=O)C1C(C)OC(C)CN31 +CN(C)CCNC(=O)c1cccc(Nc2nc3cc(C(=O)O)ccc3c3sccc23)c1 +CCN(c1ccc(OCC(C)C)c(C(C)C)c1)c1ccc(C(=O)O)cn1 +CCCOc1ccc(-c2ccc(-c3ccccc3Cl)n2CC(=O)N=C(N)NCc2cccs2)cc1 +OC(CN1CCN(C(c2ccccc2)c2ccccc2)CC1)Cn1cnc2c(-n3cccn3)ncnc21 +COc1ccccc1N1CCN(CCCCn2nc(-n3ccnc3)ccc2=O)CC1 +CC(C)(C)c1ccc(NC(=O)c2cccc(N3CCc4nc(N)ncc4C3)c2)cc1 +CC(C)(N)c1cc2nc(-c3cnc(N)nc3)nc(N3CCOCC3)c2s1 +CCc1cc(C(=O)O)c(NC(=O)c2ccc([N+](=O)[O-])o2)s1 +O=C(Nc1ccc(I)cc1)c1ccc(Cl)[n+]([O-])c1 +O=C(CCCCCCc1ccccc1)c1nc(C(F)(F)F)co1 +Cc1scnc1C(=O)Nc1ccc(N2Cc3c(Cl)cccc3C2=O)c(Cl)c1 +NC(=Nc1ccc2ccn(CCCN3CCOCC3)c2c1)c1cccs1 +O=S(=O)(CC(F)(F)F)N(Cc1cccnc1)c1cccc(OC2CCC2)c1 +CCOC(=O)C1CCC2(CC1)OOC1(OO2)C2CC3CC(C2)CC1C3 +OC1(c2ccccc2)CCN(Cc2cc3ccccc3s2)CC1 +N#Cc1cccc(-c2nc(N)c3cc(CN4CCOCC4)sc3n2)c1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cnc(Cl)c3Cl)c2)c2cncnc21 +CN(C)CCn1c(=O)c2ccc3c4c(nn3CCN3CCCC3)-c3ccccc3-n(c1=O)c24 +CCOC(=O)c1cn2ncnc(Nc3ccc(Br)c(C(=O)NOC)c3)c2c1C(C)C +CC(O)c1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1 +CC(Nc1nc(NCCc2ccc(S(N)(=O)=O)cc2)nc(NC(C)C(=O)O)n1)C(=O)O +CC(=O)Nc1cccc(-c2ccc(C(O)(c3c[nH]cn3)C(C)C)cc2)n1 +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCN(C(=O)CC(F)(F)F)C1 +CCCCCC(O)c1ccc(OCc2ccc3ccccc3n2)cc1 +CC(Cc1ccccn1)N1C(=O)c2ccccc2C1C(=O)NCc1ccc(OC(F)(F)F)cc1 +CC(Nc1cc(F)cc(F)c1)c1cc(C(=O)N2CCSCC2)cc2c(=O)cc(N3CCOCC3)oc12 +OC1C(CCl)OC(n2cnc3c(NC4CCCC4)nc(Cl)nc32)C1O +COc1ccc2cccc(OCC(=O)NCC(O)CN3CCc4ccccc4C3)c2n1 +C=C(c1cc(Cl)cc(Cl)c1OCC(O)CNC(C)(C)C)n1ccnc1 +O=C(O)CCC(c1nc2ccccc2o1)n1cc(C=CC(=O)NO)nn1 +COc1cccc(OC)c1-c1cccc2c1CCC(N(C)C)C2 +Nc1nc(OC(c2ccccc2-c2ccco2)C(F)(F)F)cc(-c2ccc(CC(N)C(=O)O)cc2)n1 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+COc1cc(-c2ccc3c(c2)Nc2ccc(CCOc4ccc(N5CCOCC5)cc4)cc2NC3=O)ccc1CC#N +NC(=O)N1CCCc2cc(-c3cncc(F)c3C3(O)COC3)cnc21 +COC(=O)COc1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC2CCC1C2 +COc1c(Cc2ccccc2)cc(-c2ccccc2)cc1C(=O)NC1CCCCCC1 +COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CCN(CC(=O)N4CC(O)C4)CC3)c(C#N)c12 +Cc1cc(CC(NC(=O)c2c(C)cccc2Cl)C(=O)O)ccc1-c1c(C)n(C)c(=O)n(C)c1=O +O=c1c2c(O)cccc2oc2ccc3c(c12)CC(C1(CO)CO1)O3 +Cn1ccnc1C(CC(=O)O)c1ccc(OCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NC3CC(N)C3)c2cn1)c1ccccc1 +COc1cc(C(=O)n2nc(Nc3ccccc3)nc2N)cc(OC)c1OC +Cc1cccc(NC(=O)Nc2ccc(-c3c(Cc4ccccc4)sc4ncnc(N)c34)cc2)c1 +CCN(CC)CCOc1ccc(NC(=O)c2cccc(-c3cccc(O)c3)c2)cc1F +CC(C)(C)OC(=O)NCCC1NC(=O)C2(C)CSC(=N2)c2csc(n2)CNC(=O)CC(C=CCCS)OC1=O +CCN(CCCCNc1ccnc2cc(Cl)ccc12)CCNS(=O)(=O)c1cccc2c(N(C)C)cccc12 +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(NC2CCOC2)nc1C1CCC1 +CCS(=O)(=O)c1cccc(Oc2cccc(-c3c(C)nc4c(C(F)(F)F)cccn34)c2)c1 +CC(=O)c1c[n+](Cc2ccccc2C)ccc1CC1Cc2cc3c(cc2C1=O)OCO3 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+O=C(NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1)N1CCC(c2ccccc2O)CC1 +COc1cccc(CNc2nc(Nc3cc(OC)cc(OC)c3)c(C(N)=O)c3nccn23)c1 +CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2F)c(=O)n(C2CCCOC2)c2ncnn12 +CN(C)CC(NC(=O)Nc1cc2[nH]nc(N)c2cn1)c1ccccc1 +CCN1CCC(CC(=O)Nc2n[nH]c3nnc(-c4cccc(F)c4F)cc23)CC1 +CN(Cc1ccc(-c2cccs2)s1)C(=O)C1CCCC1N(C)Cc1ccc(-c2ccccc2C(F)(F)F)cc1 +O=C(Nc1ncc(F)s1)C(CC1CCOCC1)c1ccc(S(=O)(=O)C2CCC2)cc1 +CC(C)(C)c1ccc(CCNc2ncnc3c(O)cccc23)cc1 +CC(=O)NC(C(=O)N1CC(O)CC1C(=O)NCc1ccc(-c2scnc2C)cc1)c1ccccc1 +O=C(c1csc(-c2ccncc2)n1)N1CCC(O)(c2ccccc2)C2CCCCC21 +CCOC(=O)c1ccc2c(c1)-n1c(-c3ccccc3)c3c(=O)n(C)c(=O)n(C)c3c1C(c1ccc(Br)o1)O2 +Cc1ccc(S(=O)(=O)N2CCCc3ccc(Oc4cc(-c5nc(C6CC6)no5)cc(Cl)n4)cc32)cc1 +O=[N+]([O-])c1ccc(NCCN(CCc2ccccn2)c2ncc(-n3ccnc3)c(-c3ccc(Cl)cc3Cl)n2)nc1 +CNc1cncc(-c2cccc3c(-c4ccc(C(N)=O)c(NC5CCC(O)CC5)c4)nccc23)c1 +COc1cccc(C2OC(CC(=O)NC(CC(C)C)C(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC +COc1cc2nc3c(c(N)c2cc1OC)CC(CNC(=O)c1ccoc1)C3 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+O=C(O)c1ccc2c(c1)nc(Nc1ccc(F)c(Cl)c1)c1ccncc12 +CN(Cc1cc(Cl)cc(Cl)c1)C1CC2c3[nH]c4ccccc4c3CCN2C(=O)C1CO +O=C(Cc1cccc2ccccc12)N1CCN(c2ccccc2)CC1CN1CCCC1 +Fc1ccc2[nH]cc(C3CCC(NCc4ccccc4)CC3)c2c1 +Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1[nH]c(C2CC2)nc1Cl +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(C(=O)OC2CCOCC2)CC1 +COc1cccc(Sc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)noc2CO)c1 +CCCN(CC1CC1)C(=O)C(NC(C)=O)C1CC(C(=O)O)CC1N=C(N)N +O=C(NCc1ccc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cn1)c1cnc2[nH]ncc2c1 +Cc1cc2c(N3CCN(CCCCN4C(=O)SC5(CCCC5)C4=O)CC3)nccc2o1 +COC(=O)c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1 +Cc1sc(NC(=O)N2CCCC2C(=O)O)c(-c2nc(C(F)(F)F)no2)c1C +Clc1ccc(NCc2cncn2Cc2ccc(-c3ccccc3)cc2Cl)cc1 +N#CC(Cc1ccc2oc3ccccc3c2c1)NC(=O)C1NC2CCC1C2 +COC1CN(c2cccc(-c3cccc(C)c3OCc3ccc4c(c3C)CCN(C3CCOC3)CC4)n2)CCC1C(=O)O +CN(C)c1ccnc2sc3c(=O)n(C4CCCCCCC4)cnc3c12 +O=C(O)C1=Cc2cc(OC(F)(F)F)ccc2OC1C(F)(F)F +CCc1nn2cc(-c3cc4cccc(OC)c4o3)nc2s1 +COCc1nc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C 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+CC(=O)OC1C(N=[N+]=[N-])C2=CC(=O)CCC2(C)C2CCC3(C)C(=O)CCC3C12 +C[N+](C)(C)CC(CC(=O)[O-])OC(=O)CCCCC(=O)Nc1ccn(C2OC(CO)C(O)C2(F)F)c(=O)n1 +O=S(=O)(c1ccc(-c2ccnc(Nc3ccc(Cl)cc3)n2)cc1)N1CCNCC1 +Clc1ccc(Sc2nnc(Cc3ccncc3)c3ccccc23)cc1 +Cn1cc(-c2nc(C3(c4ccc(-c5cnc(N)cn5)nc4)CCC3)no2)cn1 +CN(C)C(=O)c1cccc2cc(CCc3c(C(=O)O)[nH]c(=O)[nH]c3=O)ccc12 +COc1cc(C=C2CCC(=Cc3ccc(OCCCCN4CCCCC4)c(OC)c3)C2=O)ccc1OCCCCN1CCCCC1 +COc1cccc(N2CCC(NC(=O)N(C)C3CCN(S(C)(=O)=O)CC3)CC2)c1 +Fc1cccc(CSc2cc3ccccc3[n+](CCCCCC3CCCCC3)c2)c1 +COc1ccc(NCCNC(=O)C(Cc2cccc(Cl)c2)NC(=O)c2cccc(C)c2)cc1 +O=C(NC1CCCOc2c1nn(-c1ccccc1Cl)c2-c1ccc(Cl)cc1)C1CCOCC1 +COC1CN(c2nc(C(=O)N(C)C)c(C(=O)O)s2)CCC1NC(=O)c1[nH]c(C)c(Cl)c1Cl +FC(F)(F)c1cccc(-c2cn(CC3CC3)c(-c3cccc(CN4CCOCC4)c3)n2)c1 +O=C(O)C1CCCN(CCOCCN2c3ccccc3C=Cc3ccccc32)C1 +CCCN1CC=C(c2c[nH]c3ccc(C(=O)OC)cc23)CC1 +CC1(C)CN=C(c2ccc(-c3cccc(-c4ccc(C5=NCC(C)(C)CN5)cc4)c3)cc2)NC1 +COc1ccc2c(c1)c(CC(=O)O)c(C)n2C(=O)c1ccc(C(F)(F)F)cc1 +CCOC(=O)NC(=NCC1CCCCC1)NCCCc1c[nH]cn1 +COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccn(CC(=O)O)n3)cc21 +CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCOCC1)C2 +O=c1ccc2c(-c3ccccc3S(=O)(=O)O)c3ccc(O)c(O)c3oc-2c1O +Cc1cccnc1C(CC(=O)N1CCC(N2Cc3ccccc3NC2=O)CC1)Cc1cc(C)c2[nH]ncc2c1 +N=C(N)c1ccc(Oc2ccc(C(=O)N3CCC(CCN)CC3)c(Oc3ccc(C(=N)N)cc3)n2)cc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1ccnn1-c1ccccc1 +COc1cc2c(cc1N1CC(C)N(C)C(C)C1)N(C(=O)Cc1cccc(F)c1C(F)(F)F)CC2 +O=C(NC(CO)CC1CCC1)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(C)n1)CC2 +COc1ccc2c(OCc3nnc4ccc(-c5ccc[nH]5)cn34)ccnc2c1 +NCCC(NC(=O)OCc1ccccc1)C(=O)Nc1ccc2nc(N3CCNCC3)[nH]c(=O)c2c1 +Cc1nc2ccc(CNc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3F)cc2c(=O)[nH]1 +c1cc(NC2CCCNC2)nc(-c2cnc3ccccn23)c1 +CC(C)(C)OC(=O)NCc1ccc(C(=O)NC2CCOC2=O)cc1 +CC1(c2ccc(C(=N)N)cc2)NC(=O)N(CC(=O)NC(CC(=O)O)c2ccc3c(c2)OCO3)C1=O +NCC(=O)N1CCN(c2ccncc2NC(=O)c2nccnc2N)CC1 +COc1cccc(OC)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCC(C)CC1 +Cc1ccc(Nc2nc(N)c(C(=O)c3ccccc3)s2)cc1 +COc1cc(N2CCNCC2)c2c(c1)N(S(=O)(=O)c1ccccc1F)CCO2 +N#Cc1cnc2c(Nc3cc(F)c(F)c(C4(CF)CC(C(F)(F)F)OC(N)=N4)c3)nccc2c1 +O=C(NCCCCCCCCn1cc(-c2cccnc2)nn1)Nc1ccccc1-c1ccccc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(CC=Cc2ccccc2)CC1 +O=C(CCCCCCc1ccccc1)c1nnn(-c2cccs2)n1 +CN(C)C(=O)CCCCc1ccc(C(=O)Nc2sc(-c3ccncc3)nc2C(N)=O)cc1 +CCCC1NCCOc2ccccc2CCCNC(=O)C(Cc2ccccc2)NC(=O)C2(CCCC2)NC1=O +CN(C(=O)Nc1ccn(-c2ccccc2F)n1)C1CCC2(CC1)OCc1ccccc12 +Cc1cc(OCC2(C(=O)O)CCC2)ncc1-c1ccc(-c2nc(C(F)(F)F)c[nH]2)c(Cl)c1 +O=C(c1ccc(Cl)cc1Cl)N1CCn2c(nnc2-c2ccc(F)cc2F)C1 +COC(c1ccc(F)cc1)(c1ccc(F)cc1)c1cnn(C(=O)N2CCCCC2Cc2ccccc2)n1 +CC(Oc1cccc(Cl)c1)C(=O)N(CC1CCCN1)c1ccccc1Cl +COc1cc(C=NNc2nc(Nc3ccc(C)cc3)nc(-n3nc(C)cc3C)n2)cc(OC)c1OC +N#CCC(=O)N1CCCC(n2nnc3cnc4[nH]ccc4c32)C1 +O=C1NCN(c2ccccc2)C12CCN(C(c1ccccc1Cl)c1ccccc1Cl)CC2 +Cc1cc(CCN2CCCC2)c(C)c2c1N(CCN1CCCCC1)C(=O)C2=NNC(=O)C(C)c1ccc(O)cc1 +COCCCN1C(C=Cc2ccc(-n3cnc(C)c3)c(OC)c2)=NOC1(C)c1ccc(F)cc1 +O=C(c1ccc2c(c1)[nH]c(=O)c1cnn(C3CCCC3)c12)N1CCc2cc(Cl)ccc21 +COc1cc2c(N)nc(N3CCN(C(=O)CC(c4ccc(F)cc4)N4CCCC4)CC3)nc2c(F)c1OC +Cc1cccc(NCc2nc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)[nH]2)c1 +CSc1ccc(CN2CCC(Oc3ccc(C(=O)N4CCCC4)cc3)CC2)cc1 +NCCc1c[nH]c2ccc(Cc3nc(-c4ccccc4)no3)cc12 +O=C(Nc1cccc2[nH]ncc12)NC1CCc2cc(Cl)ccc21 +CCC(Oc1nc(-c2ccc(OC(C)C)c(OC)c2)cc2ncccc12)C1CNC(=O)C1 +O=C(Nc1ccc(F)cc1F)Nc1cccnc1Oc1cccc(C(F)(F)F)c1 +CC(C)Oc1cc(CCC(=O)NS(=O)(=O)C2CCCCC2)n(Cc2ccc(Cl)cc2Cl)n1 +ON=Cc1c(O)ccc(-c2ccc(O)cc2)c1-c1ccc(O)cc1 +CN1CCN(CCCCOc2ccc(N3C(=O)C(=Cc4ccc(Oc5ccc(C(N)=O)cc5)cc4)SC3=S)cc2)CC1 +CCc1c(-c2cncc(C)c2)nn2c1N(C)C(=O)CC2 +CC(C)(O)Cn1cc(-c2cc(CO)c3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +O=C(Nc1ccccc1)N1CCN(Cc2cccc(Oc3cccc(Cl)c3)c2)CC1 +CCCSc1nc2c(c(Nc3ccc(C(F)(F)F)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +Nc1ncnc2c1ncn2C1OC(OCP(=O)(NC(Cc2ccccc2)C(=O)OC2CCC2)Oc2ccccc2)C=C1F +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OC[Si](C)(C)c2ccc(F)cc2)c1 +CC(C)(CO)Nc1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +CS(=O)(=O)Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F +CCOCCNC(CC(C)C)C1(c2ccc(Cl)c(Cl)c2)CCC1 +CC(C)(C)NCC(=O)N1CCCC1C(=O)c1nnc(C2(C)CCCCC2)o1 +N#Cc1ncc(F)c(N(Cc2ccc3c(c2)OCO3)C2CCSCC2)n1 +COc1ccc(Nc2c(C(N)=O)cnc3cc(-c4ccncc4)ccc23)cc1 +CCOC(=O)c1cnc2c(OC)cccc2c1Nc1ccc(OC)c(OC)c1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2CCC(=O)Nc1cnc2ccccc2c1 +CNC(=O)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +COc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1cc(F)cc(-c3cccnc3)c1)CC2 +COc1nc(-c2ccccc2C(F)(F)F)cc2nc(-c3cc(C(C)(C)C)nn3C)[nH]c12 +N=C(N)NCCCC(NC(=O)CN1CCN(S(=O)(=O)c2cccc3cnccc23)CC1=O)C(=O)c1nccs1 +O=C1OCc2cc(CCN3CCN(CCc4ccc5c(c4)COC5=O)CC3)ccc21 +COc1cc(C=Cc2ccc3cccnc3c2)cc(OC)c1OC +CCOC(=O)c1ncn2c1Cn1ncnc1-c1cc(C)ccc1-2 +COC1CN(C2CCN(C(=O)c3nccc4ccccc34)CC2)CCC1Cc1ccc(Cl)c(Cl)c1 +COc1ccc2c(Oc3ccc(NC(=O)c4c(C5CCCN5)n(C)n(-c5ccccc5)c4=O)cc3F)ccnc2c1 +CCN(CCOC)c1ccc(OC)c2nc(-c3c(OC)cc(COC)cc3OC)c(C)cc12 +COc1ccc(OC)c(S(=O)(=O)n2cc(CCN(C)C)c3cc(OC)ccc32)c1 +Cc1ccc(NC(=O)NC2COC(C)(C)OC2c2ccccc2)c(C)c1 +CCN1c2ncc(CCOc3ccc(C(=O)O)cc3C)cc2C(=O)N(C)c2ccc(Cl)nc21 +NC1(C(=O)NC(CCCN2CCCC2)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 +Cc1cn(CCCNc2cccc(C)c2-c2ccc(F)cc2)cn1 +COc1cccc(COc2ccc(CCCNC(C)=O)cc2OC)c1 +O=C(Nc1ccccc1)OCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1 +COC12CCC3(CC1C(C)(C)O)C1Cc4ccc(O)c5c4C3(CCN1CCCF)C2O5 +COc1cc(OC)c2c(c1)OC(c1cc(OC)c(OC)c(OC)c1)C(OC(=O)c1cc(OC)c(OC)c(OC)c1)C2 +CC1CN(Cc2ccc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)cc2)CC(C)N1 +CCc1ccccc1C1CCN(Cc2cccnc2)C(c2ccc(O)c(NCc3ccccc3)c2)C1[N+](=O)[O-] +CN1N=C(c2ccc(O)cc2O)CC1c1ccc(Cl)cc1 +COc1ccc2nc3[nH]nc(C)c3c(CN3CCCOCC3)c2c1 +Cc1c(-c2ccccc2F)nc2cc(Cl)ccc2c1N1CC2(CCOCC2)c2ccc(N3CCOCC3)cc21 +COc1ccc(S(=O)(=O)n2c(C)c(CC(=O)NCCCN3CCN(C)CC3)c3cc(F)ccc32)c(C)c1C +O=C(Cc1ccc(O)c(F)c1)NN=C1C(=O)Nc2ccccc21 +CN1CCN(CCCN(c2nc3cc(F)c(F)cc3[nH]2)C2CCC3(c4cccc(CN5CCCC5)c4)CC3C2)CC1 +CS(=O)(=O)c1ccc(-c2cnc3ccc(-c4cccc(S(=O)(=O)C5CC5)c4)nn23)cn1 +CC(C)(C)OC(=O)N1CCC(NC(=O)C2C(C(=O)Nc3ccc(Br)cc3)C3C=CC2C32CC2)CC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N4CC5CC4CO5)ncc3F)C2)cc1 +COc1ccc(NC(=O)C(=O)c2c[nH]c3cc(Cl)ccc23)cc1 +C=CC(=O)N1CCCC(n2c(NC(=O)c3cccc(C(F)(F)F)c3)nc3cc(C)ccc32)C1 +CCn1c(=Cc2scc[n+]2Cc2ccccc2)sc(=C2Sc3cccc(F)c3N2C)c1=O +CCOC(=O)C1=C(CN2CCOCC2CO)NC(c2nccs2)=NC1c1ccc(F)cc1Br +CCOC(=O)C(=CNc1ccc2ncnc(Nc3ccc(Oc4cccc(C(F)(F)F)c4)c(Cl)c3)c2c1)C(=O)OCC +CCOC(=O)c1c(C(=O)OCC)c2c(-c3ccccc3)cc(N3CCOCC3)nn2c1COC +COc1ccc(OCCOc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 +Cc1ccc(-c2cccc3cnc(Nc4ccc(-n5cnc(C)n5)cc4)nc23)cn1 +COC(=O)CNC(=O)C=CCC=CNC(=O)C=C(C)C=CC(C)C(OC)C(C)C(C=Cc1ccccc1)OC +CN(C)Cc1cc(C(=O)NC2CCc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cc3C2)cc(C(F)(F)F)c1 +CN(C)c1ccc(CN(C2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 +O=C(O)Cc1sc(Cc2cccc3ccccc23)nc1-c1ccc(Cl)cc1 +COc1cc(Cc2cnc(N)nc2N)cc2c1N(CCOC(C)=O)CCC2C +CC(C)C(=O)OC1C=C2c3cc4c(c(O)c3C(=O)NC2C(O)C1O)OCO4 +CCCCC1=NC2(CCN(C(=O)C(F)(F)F)CC2)C(=O)N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cc1cccc(Cl)c1Nc1nc2c(Nc3ccc(C(F)(F)F)cc3)ncnc2s1 +CC(=O)c1cnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc2c1NC(C)C 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+N=C(N)c1cc2c(OC(COC(=O)Nc3cccc(F)c3)c3ccccc3)cccc2s1 +Cc1cc(C)[n+](CC(=O)OCCc2ccc(S(N)(=O)=O)cc2)c(C)c1 +CCc1c(Cc2ccccc2)nc(SCC(=O)c2ccc(OC)cc2)[nH]c1=O +COc1ccc(S(=O)(=O)NCCc2cccc3cc(F)ccc23)cc1N1CCNCC1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CC(F)(F)C(F)(F)C3)ns2)n1 +O=C1C(N2CCCCC(c3ccc(O)cc3)C2)CCN1Cc1ccc(F)cc1 +CCCCCCCNC(=O)Oc1ccc2c(c1)CN(C)C(c1cccc(C)c1)N2C +CNc1n[nH]c2ccc(C(=O)N3CCCC3c3ccc(Cl)cc3)cc12 +CN(C(=N)Nc1cccc2ccccc12)c1cccc(Br)c1 +Cc1noc(C)c1Cn1cc(NC(=O)c2cccc(Cl)c2)cn1 +CCc1cc(C=CC(=O)O)ccc1NC(=O)c1cccc(NC2=NCCN2)c1 +CCCc1cc(C2=NC3OCCCC3S2)ccc1OCCCOc1ccc2c(c1)CCC2CC(=O)O +CC(C)(C)c1cc(-c2ccccc2)cc(-c2ccccc2)[n+]1Cc1ccc(S(N)(=O)=O)cc1 +CCN1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 +Cc1cc(NC(=O)C(C#N)=C(O)C2CC2)ccc1C#N +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCC5CC5)s4)nc23)N1 +CC(NC(=O)CCc1nc2ccncc2n1Cc1ccc(OC(F)(F)F)cc1)c1ccc(Cl)cc1 +C(=CCN(CC1Cc2ccccc2CN1)C1CCCc2cccnc21)CNCc1ccncc1 +CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1C1CCC(F)(F)C1 +COc1cc(OCCN2CCc3ccccc3C2)ccc1C=NNC(=O)c1ccc(O)c(Cl)c1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1 +CCCn1c(=O)c2nc(C3CCc4ccccc4C3)[nH]c2n(CCC)c1=O +CC(C)C1c2[nH]cnc2CCN1C(=O)OCCOc1ccccc1 +CN1C(=O)c2ccccc2[S+]([O-])c2ccc(C(=O)NCc3cccnc3)cc21 +O=C(NCc1ccc(Br)cc1OC(F)(F)F)c1ccc(OCCC(F)(F)F)nc1 +CS(=O)(=O)Nc1cccc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC3(C#N)CC3)n2)c1Cl +COc1cccc(C(=N)NCCCCCCCCCCCCNC(=N)c2cccc(OC)c2)c1 +COc1c(OCC(C)(C)OC)ncnc1N1CCC(Oc2ccc(C(C)NC(C)=O)cc2)C1 +O=C(C=Cc1ccc(C(F)(F)F)nc1N1CCCCC1)Nc1ccc2c(c1)OCCO2 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(N2CCOCC2)cc1 +O=S(=O)(NCc1ccco1)c1ccc(NC2CC3CCC2C3)cc1C(F)(F)F +O=S1(=O)c2cccc3cccc(c23)N1CCCN1CC=C(c2c[nH]c3ccc(O)cc23)CC1 +COc1ccc2c(c1)c(CN1CCNCC1)cn2S(=O)(=O)c1ccccc1Br +COCC1CN(c2n[nH]c3cc(NC(=O)NC(C)c4ccccc4)ncc23)C1 +Cc1nsc(-c2nnc3n2CCN(C(=O)c2ccc(F)c(F)c2)C3C)n1 +CC(=O)N(C)Cc1cc(-c2ncco2)ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C +COCC(COC)N1CCc2cn(-c3ccc(Cl)cc3C#N)c3nc(C)cc1c23 +COc1cc(O)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(=O)NC1CCS(=O)(=O)C1 +CCCOCCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +O=C(NCc1cc(Br)cc2nc(O)c(O)nc12)c1ccncc1 +Cc1nc(-c2c(F)cc(Cl)cc2-c2cnc(C(C)NC(=O)C3(NC(=O)c4nnc(C)o4)COC3)c(F)c2)no1 +Cn1c(=O)c2c(nc(C=Cc3ccc(Cl)cc3)n2C)n(C)c1=O +Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4n3)c2)on1 +COc1cccc(N(C(C)c2ccccc2OCCCN2CCCC2)S(=O)(=O)c2ccc(Cl)cc2)c1 +CCCCCCCCCCCCc1cc(C(C(=O)Nc2c(C(C)C)cccc2C(C)C)c2ccccc2)on1 +CC(=Nc1ccc2c(c1)C(NC(=O)c1ccc(Br)cc1)C(O)C2)NCCc1ccc(F)cc1 +Cc1cnc(N2CCN(CCC3CCC(NC(=O)C4CCOCC4)CC3)CC2)c2ccoc12 +COC(=O)NCc1cc(-c2sc(-c3cccnc3)nc2N2CCCCC2)n[nH]1 +Cc1cc(C2CCN(C)CC2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 +O=C(Nc1ccc(-c2nc(N3CCOCC3)c3cccnc3n2)cc1)Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1 +CN1CC=C(c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)CC1 +COc1cccc(S(=O)(=O)Nc2cc3c(cc2Oc2ccccc2)n(C)c(=O)n3C)c1 +CCOc1cc(NC2(CCCN)CC2)c2nc(C(F)(F)F)ccc2n1 +CC(C)(C)C(=O)CS(=O)(=O)c1cnnn1-c1ccccc1 +Cc1nnc2n1-c1c(F)cc(-c3cncc(F)c3)cc1CC2 +CNc1cccc(Nc2nc(N)c(C(=O)c3cccc(F)c3)s2)c1 +N#Cc1c[nH]c2nc(Nc3ccccn3)cc(-c3ccccc3)c12 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3ccc(C4CC4)cc3)cc2)C1CO +NCCCC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1 +Cc1cc(N2CCCC2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +Nc1nc(SCCO)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 +O=C(O)c1ccc(NC(=O)c2nc3ccccc3nc2Oc2ccc(F)cc2F)cn1 +COc1ccnc2c1C(=O)c1c(-c3ccccc3NC(=O)C(F)(F)F)ccnc1C2=O +CN1CCN(C2CC(c3ccc(F)cc3)c3ccc(C(F)(F)F)cc32)CC1(C)C +CCC(O)=C(C#N)C(=O)Nc1ccc(-c2cccnc2)c(C(=O)OC)c1 +CC(C)CN1CCN(c2nc3c(c(Nc4ccc(C(F)(F)F)cc4)n2)CCN(c2ncccc2C(F)(F)F)CC3)CC1 +Cc1ccccc1-c1ccccc1C=NNc1c(Cl)cncc1Cl +CCCCCCSCC1C2CCC(O2)C1CC=CCCCC(=O)O +COc1cc(C(=O)NC(Cc2ccccc2)C(O)CO)ccc1-c1cn[nH]c1 +CC(C=NOCCCN)=CC1CCC2(O)C3CCC4CC(O)CCC4(C)C3CCC12C +CC(C)N1CCc2nc(O)n3nc(-c4ccccc4F)nc3c2C1 +CC(C)Cn1c(=O)n(C)c(=O)c2c(S(=O)(=O)N3CCC(O)C3)c(Cc3ccccc3C(F)(F)F)sc21 +Cc1cc(SSc2cc(C)nn2-c2ccccc2)n(-c2ccccc2)n1 +COc1ccc(C2(Cc3ccncc3)CCNC2=O)cc1OC1CCCC1 +O=C(CN1CCCCC1)N1CCc2nc(O)c3ccccc3c2C1 +CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCC(C)C4)n3)cc2)C1=O +COC1CCN(C(=O)c2ccc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)cc2F)CC1 +O=C(O)CC(NC(=O)CNC(=O)c1cncc(NC2=NCC(O)CN2)c1)c1cc(Cl)cc(I)c1O +COc1ccc(NC(=O)Nc2ccc(C(F)(F)F)cc2)cc1-c1c(Br)cnn1C +CCCCNC(=O)c1cnc(N2CCN(C3CCN(Cc4ccc(Cl)cc4)CC3)CC2)c(Cl)c1 +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1nccs1 +O=c1[nH]n(Cc2ccncc2)c(=O)c2c(=O)c3ccc(Cl)cc3[nH]c12 +Cc1nc(N)ccc1CNC(=O)C1C=CCn2c(=O)n(C(CSc3ccc(Cl)cc3)C(=O)O)c(=O)n21 +Cc1ccc(OCC(=O)NC2c3cc(NC(=O)COc4ccc(C#N)cc4C)ccc3CC2O)cc1 +O=C(C(c1ccc(Cl)cc1)c1cccnc1)N1CCN(c2nccs2)CC1 +CCOc1ccc(CC(NC(=O)c2ccccn2)C(=O)NC(Cc2cccs2)C(=O)NCc2ccc(CN)cc2)cc1 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1ccc2c(c1)ncn2Cc1ccccn1 +CCS(=O)(=O)c1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2CN2C(=O)COC2=O)cc1 +N#CC1(NC(=O)C(Cc2ccc(Cl)c(Cl)c2)NC(=O)c2cnn(C3COC3)n2)CC1 +NC(CNc1cc(-c2ccncc2)c(-c2cccc3ccccc23)nn1)Cc1ccc(F)cc1 +Oc1nc2cc(C#CCN3CCC(CCc4ccc(F)cc4)CC3)ccc2[nH]1 +CCC(NC(=O)c1ccc(C(=N)N)cc1)C(C)(C)C(=O)N1CCC(CC(=O)O)CC1 +Cc1cn2cc(C(F)(F)F)cc2c(C#Cc2ccc(F)cc2)n1 +CCOc1ccccc1C(=O)c1cnc(NC2CCN(C(C)=O)CC2)nc1N +Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccnnc3)c1)=N2 +COc1cc2c(cc1OC)CN(Cc1ccc(-c3ccc(O)cc3)cc1)CC2 +Cc1[nH]cnc1CSCC(=O)NC(=N)NCCCc1c[nH]cn1 +COC(=O)c1c(Cl)cc(Cl)cc1-c1ccc(C(C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1 +COc1cnc(N2CCOCC2)c2sc(NC(=O)C(C)(C)Oc3ccc4c(c3)OCO4)nc12 +N#CC1CCCN1C(=O)C(N)CCC(=O)N1CCc2ccccc2C1 +Cc1ccc(C=CC(=O)NC(Cc2ccccc2)C(=O)NC(C=O)CC2CCNC2=O)cc1 +COc1c(C)cnc(CN2c3nc(N)nc(Cl)c3NC(=O)C2C(C)C)c1C +O=C(CSc1nc2ccccc2s1)N1c2ccccc2Sc2ccc(C(F)(F)F)cc21 +N#CSc1ccc(CCCN2CCN(CCCN(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1I +Fc1ccccc1N1CCN(Cc2cnn(-c3ccccc3)c2)CC1 +COc1cc(C2c3cc4c(cc3C(CCN(C)N(C)C)C3COC(=O)C23)OCO4)cc(OC)c1O +CC(C)n1cc(-c2cccc(-c3cnc(N)c(C(=O)NC4C5CC6CC4CC(O)(C6)C5)n3)c2)cn1 +COCCNC(=O)Nc1cc2[nH]nc(-c3cc(C)nc(OC)c3)c2cn1 +CCC1(CC)CC(=O)C(C2C3=C(CC(CC)(CC)CC3=O)Oc3ccccc32)=C(O)C1 +Cc1cc(-c2ccc3c(c2)CCN(CCCSc2nnc(-c4cccn4C)n2C)CC3)no1 +CCC(CC(O)C(N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NCC1(CO)CCCC1 +CC(=N)N1CCC(Oc2ccc(NCC(C)=Cc3cccc(C(=N)N)c3)cc2[N+](=O)[O-])CC1 +Cc1cc(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2)nc(C)n1 +O=C1C(=NNc2cccc3c(=O)[nH][nH]c(=O)c23)C(c2ccccc2)=NN1c1ccccc1 +NS(=O)(=O)c1nnc(NC(=O)CCNC(=O)c2c(F)c(F)c(F)c(F)c2F)s1 +CC1CCC2C(C)C(OC(=O)c3ccc(C=CC(=O)c4ccccc4)cc3)OC3OC4(C)CCC1C32OO4 +Clc1ccc(-c2ccc(C#Cc3ccc(OCCN4CCCC4)cc3)nc2)cc1 +Clc1cc(Nc2nc(NCc3ccccc3)c3ccccc3n2)ccc1Br +COc1cc(-c2cn[nH]c2)ccc1NC(=O)C1COc2ccc(C)cc2C1 +COC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4ccsc4)c(F)cc3C)cc1OC2 +CCCc1cc2c(cc1N1CCN(C3CCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +O=C(Nc1cccc2nsnc12)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OC4CCCC4O)c3)C2)cc1 +COc1cc(-c2ccc(F)c(C)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccnc(C)n3)ccc21 +O=C(CSc1nnc(Nc2ccccc2)s1)NN=Cc1ccc(-c2cccc(Cl)c2)o1 +CCOc1ccc(S(=O)(=O)N2CCN(CCO)CC2)cc1-c1nc(O)c2nnc(C3CCCC3)n2n1 +COc1cc(Cn2nc(C(=O)O)cc2C)c2nc(N3CC=CCC3)sc2c1 +Oc1ccc(-c2c(-c3ccc(OCCN4CCCCC4)cc3)nn3c(C(F)(F)F)cc(C(F)(F)F)nc23)cc1 +CCC(=O)Oc1cccc(-c2nc(N3CCOCC3)c3cc4ncccc4n3n2)c1 +Cc1cc(Br)cc(C)c1Oc1cc(Nc2ccc(C#N)cc2)nnc1Cl +CN(CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21)Cc1coc2ccccc12 +Cc1cccc(CNc2nc(-c3ccccc3C(C)C)ncc2C)c1 +CCNC(=O)c1c(C2CC2)nc(CC)n1Cc1ccc2oc(-c3ccccc3NS(=O)(=O)C(F)(F)F)c(Br)c2c1 +CN(C)C1(C(=O)Nc2cccc(-c3ccncc3)c2)CCN(c2ncnc3[nH]c4c(c23)CCCC4)CC1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCN(C)CC2)n1 +CCOc1cc(CN2CC3(CC(c4ccc(CO)cc4)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +CCN(CC)S(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1 +COC(=O)c1oc(C(C)(C)C)cc1NC(=O)Nc1ccc(C)cc1 +Cn1cc(S(=O)(=O)c2ccc3c(c2)c2c(n3C)CC3CCC2N3)c2ccccc21 +Nc1ccnc(N2CCC(NC(=O)C3CCCO3)(c3ccccc3)CC2)c1 +NS(=O)(=O)Oc1ccc2cc(-c3cc(F)c(F)c(F)c3)c(=O)oc2c1 +[C-]#[N+]C1=C(C)Nc2oncc2C1c1ccc2[nH]nc(OC)c2c1 +COc1ccc(C2C(c3ccc(NC(=O)C(N)CCCCN)cc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1 +COCCNc1ncc(Oc2cc(I)c(OC)cc2C(C)C)c(N)n1 +Cn1c(=O)c2c(nc(COc3cccc(Br)c3)n2C)n(C)c1=O +CC(NC(C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)O)C(C)C)C(=O)O +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CCN(C(=O)NC(C)(C)C)C1)CC2 +CC1(O)CCCN(S(=O)(=O)c2ccc(OCc3ccc(F)cc3Cl)cc2)C1C(=O)NO +C=CCCCCCCCCCCCCCCOCCOP(=O)(O)COC(CO)Cn1cnc2c(N)ncnc21 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1CCCc2ccc(C(C)(C)C)cc21 +COc1cc(-c2cncc(NC(C)c3cccc(NC(=O)c4cccnc4)c3)n2)ccc1O +NC(=O)c1cc(-c2cnc(Nc3ccc(N4CCOCC4)cc3)c3nccn23)co1 +CCOC(O)=C1C(COCCN(C)C)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +O=C1c2cccnc2-c2nccc3c2c1nc1ccc(N(CCCl)CCCl)cc13 +O=c1ccc2c(N3CCN(CCCCOc4ccn5nccc5c4)CC3)ccc(O)c2[nH]1 +OCCCc1n[nH]c2c(Cl)ccc(Nc3c(-c4ncccn4)oc4cnccc34)c12 +COc1cc(N2C(=O)c3ccc(-c4ccccc4)cc3C2=O)ccc1OCCN(C(C)C)C(C)C +CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1CC2OCOC2C1)S(=O)(=O)c1ccc(CO)cc1 +O=C(Nc1cc(Cl)c(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1Cl)Nc1ccccc1Br +O=C(NC(c1ccc(Cl)c(F)c1)C1CCCN1)c1ccc2cnc(NC3CCOCC3)nc2c1 +NC(=O)c1sc2nc(NC3CC3)nc(-c3cccc(O)c3)c2c1N +O=C(OCc1ccoc1)c1cnn2c1n[n+]([O-])c1ccc(Cl)cc12 +CC(C)(C)c1cc(NC(=O)Nc2cc(Br)cc(Br)c2)no1 +CN(C)CCC(NC(=O)C=Cc1ccccc1)c1ccc(Cl)cc1 +CCC1CCCC(C2(CC(=O)N3CC4CCC(C3)N4C)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCCCC(CC)CNc1ncc(C(=O)OCC)c2nc(-c3ccco3)nn12 +CC(c1ccc(F)c(OC(F)(F)F)c1)N1C(=O)CS(=O)(=O)c2ccsc21 +Cc1cccc(OCC(=O)N2CCN(c3nc(N)nc4sccc34)CC2)c1 +C#Cc1cccc(Nc2nc3cc(-c4nnn[nH]4)ccc3c3sccc23)c1 +COC1CCCN(c2cc(-c3n[nH]c4ccc(OC(C)C)cc34)ncn2)C1 +COc1ccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cc1Cl +O=C(C=Cc1ccc(N2CCCCC2)cc1)c1ccc(OC(=O)N2CCCC2)cc1O +COC1C(=O)N(C(C)=O)C1C(C)=Cc1ccccc1 +CS(=O)(=O)Oc1cccc(CC2CN=C(N)N=C2N)c1 +Fc1ccc(Cn2c(N3CCC(n4cccn4)CC3)nc3ccccc32)cc1 +CCn1c(=O)n(C(=O)NCCN2CCN(C(C)C)CC2)c2ccccc21 +NS(=O)(=O)c1ccc(C2=C(c3ccc(C(F)(F)F)cc3)CC3(CC3)C2)cc1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(F)nc4)cc23)c1F +CC(C)OC(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +O=C(Cn1c(-c2ccc(Cl)cc2)nc2cccnc21)Nc1ccccn1 +CCn1nc2c(c1C)OC1(CCN(C(=O)c3cc(C)c4[nH]nc(C)c4c3)CC1)CC2=O +CCCS(=O)(=O)Nc1ccc(Cl)c(-c2cc3cnc4[nH]ncc4c3cc2OC)c1Cl +O=C(Nc1cc2[nH]nc(OCC(F)F)c2cn1)NC(c1ccccc1)C1(O)CCCC1 +CCC(C)C(N)C(=O)N1C[S+]([O-])CC1C#N +COC(=O)C1C(C=Nc2ccc(OC)cc2)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +Cc1c(C(=O)OC(C)C(C)(C)C)cn2c1C(=O)N(CCF)CC2 +O=C(COc1cccc2[nH]cc(Sc3ccc(F)cc3Cl)c12)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +CCC(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +Cc1cc(C(=O)NC(CC(=O)NCC(C)(C)C)C(=O)NC(CCc2ccccc2)C(=O)NCc2ccccc2)no1 +N#Cc1c(NNC(N)=S)nc(SCc2nc3ccccc3[nH]2)nc1-c1ccccc1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-n3cccn3)cc2)c1C +Cc1nc(-c2c(F)cc(Cl)cc2-c2cnc(C(C)NC(=O)C3(NC(=O)c4ccno4)COC3)c(F)c2)no1 +CCOc1cc2c(-c3cccc(S(N)(=O)=O)c3)n[nH]c2cc1-c1cn[nH]c1 +CN(N=Cc1cc(Br)cc(Br)c1O)c1cccc(C(F)(F)F)n1 +CCCCC1=NC(C)(C)C(C(=O)OCC)=C(Cl)N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(c1ccc(OCc2ccccc2)cc1)N(CCc1ccccc1Cl)C1CCNC1 +CCN(C)C(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(N(CCN(C)C)S(C)(=O)=O)cc1)c1ccccc1 +OC1CCC(Nc2cc(-c3cccc(NCC4CCCNC4)n3)c(Cl)cn2)CC1 +CC1(C)C2CCC(C[N+](C)(C)Cc3ccc(-c4ccccc4I)cc3)C1C2 +CC(C)(C)NC(=O)c1ccccc1CC(O)C(Cc1ccccc1)NC(=O)C(CSCc1ccccc1)NS(C)(=O)=O +Nc1nccn2c(C3CCCCC3)nc(-c3ccc(Oc4ccccc4)cc3)c12 +Cc1cc(Oc2ncccc2F)ccc1-c1c(C)c(=O)[nH]c(=O)n1C +CSc1nn2cc(-c3cc4c(OCc5cccc(OCc6ccccc6)c5)cc(OS(=O)(=O)C(F)(F)F)cc4o3)nc2s1 +CON(C)C(=O)C=Cc1ccc(C(=O)NCc2ccccc2C(F)(F)F)cc1 +CCN(CC)CC1CCCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)C1 +CCCC12CCC(=O)C(Br)=C1c1ccc3[nH]ncc3c1C2 +CNC(C)C(=O)Nc1ccc2c(n1)CN(C1CCN(C(C)=O)CC1)C(=O)N2c1cccc(Cl)c1 +COCCN(C)C(C)(C)c1ccc(NC(=O)c2ncc(C#N)[nH]2)c(C2=CCC(C)(C)CC2)c1 +CCCNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc3C)CC2)ncn1 +C=C(c1ccccc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +COc1cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)ccc1F +C=C(C)n1c(=O)n(Cc2nc3cc(C(=N)N)ccc3n2CCC(C)C)c2ccccc21 +O=C1NC(C(=O)O)CCCCCCc2cccc(c2)CC1CS +CCCCC(Sc1nc(OCCc2ccccc2)cc(OCCc2ccccc2)n1)C(=O)O +N#Cc1ccc(-c2ccc(C(=O)N(Cc3ccccc3-c3cccnc3)c3ccc(N4CCNCC4)cc3)o2)cn1 +CC(C)=CCCC(C)=CCOC(=O)C=Cc1ccc(O)c(O)c1 +O=C(OC1CCCCC1OC(=O)c1cc(O)c(O)c(O)c1)c1cc(O)c(O)c(O)c1 +COCC[n+]1ccc(CCC(=O)C2Cc3cc(OC)c(OC)cc3S2)cc1 +COc1cc(C=NNc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)ccc1OC(=O)c1ccco1 +Nc1nccc(-c2c(-c3ccc(F)cc3)nn3ccccc23)n1 +CCCn1cc(-c2cn3ncc(C(N)=O)c(NC4CN(C(=O)C5(C#N)CC5)CC4C)c3n2)cn1 +Cn1cc2c(nc(N3CCCCC3)n3nc(-c4ccco4)nc23)n1 +CCCn1c(=O)c2nc(-c3cnn(Cc4cc(-c5ccc(OC)cc5)on4)c3)[nH]c2n(CCC)c1=O +CN1C(=CC=Cc2oc3ccc(Cl)cc3[n+]2C)Sc2ccc(Cl)cc21 +CC(C)CC(CC=C1CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC1=O)CC(C)C +Fc1ccc(-c2n[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOCC4)N3)n2)cc1 +CC(C)C1CCC(N2CCC3(CC2)C2CN(c4ccccc4)CC2CN3c2ccccc2)CC1 +COc1ccc(-c2nc(C(=O)NCCCCC(=O)NO)cc3c2[nH]c2ccccc23)cc1 +N#Cc1cc(-c2ccnc(N)n2)ccc1OCc1ccc(F)cc1C(F)(F)F +COc1ccc(CSc2nc(O)c(C)c(Cc3c(F)cccc3F)n2)cc1 +Nc1nc(-c2cccc(C(=O)NCCc3ccc(O)cc3)c2)cn2nc(-c3ccco3)nc12 +COc1ccc2cc3[n+](cc2c1OCCC(=O)Nc1ccccc1)CCc1cc2c(cc1-3)OCO2 +CC(=O)NC(C)c1ccc(OC2CN(c3ccc(C(C)(C)C)cc3)C2)cc1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C#N)ccc43)s2)c1 +O=C(Nc1n[nH]c2nc(-c3cccs3)c(Br)cc12)C1CC1 +CC(C)c1nn2ccccc2c1Cc1ccc(C(=O)NC2CCOCC2C(=O)NO)cc1 +CCOCC(NC(=O)CCN)c1cc(F)ccc1N1CCN(C(=O)CCc2ccc(Cl)cc2Cl)CC1 +COc1ccc(Nc2nnc(-c3cccnc3NCc3ccccn3)o2)cc1 +COc1ccc(S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2C(=O)NO)cc1 +CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCc2ccccc2)CC1C +N#Cc1ccc(Cn2cc(C(=O)C(=O)Nc3ccc4ncccc4c3)c3ccccc32)cc1 +COc1ccc2ncc(-c3ccc(C(F)(F)F)cc3)n2n1 +CCc1[nH]c(=O)c(Cc2ccc3oc4ccccc4c3c2)c2cc(OC)c(OC)cc12 +CCCc1nc(-n2cccc2C(=O)O)c(C(N)=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1coc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)F)c1 +Cc1cc(C(=O)N(C(=S)OCCN2C(=O)c3ccccc3C2=O)c2ccc(Cl)cc2)ccc1Br +Cc1ccc(C(=O)n2nc(-c3cccnc3)nc2N)cc1 +OCC1C2CN(Cc3ccccc3)C(c3ccccc3)C2C1N1CCCC1 +CCCn1c(=O)n(Cc2ccc(N=[N+]=[N-])c(I)c2)c(=O)c2[nH]c(-c3ccc(OCC(=O)O)cc3)nc21 +NC1=NC(=O)C2CCCN2c2ccc(cc2)OCC=CCCCNCC(=O)Nc2c(Cl)cc(cc2Cl)CN1 +O=C(NC1CCCCCC1)C1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1 +COc1cc2c(N)nc(N3CCN(C(=O)CC4CCCNC4)CC3c3ccccc3)nc2c(F)c1OC +COc1cc(C=C2COc3ccc(Br)cc3C2=O)cc(OC)c1 +CCCOCCn1c(=O)c(NCCOCC)nc2cnc(-c3ccc(OC)nc3)cc21 +CN(C)Cc1ccc(CN2CCN(c3ccc(C(=O)NO)cc3)C2=O)cc1 +O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1)c1ccc2nn[nH]c2c1 +CC1(C)C=C(Cn2cnc3c(C(N)=O)cccc32)C(C)(C)N1O +NC(=O)C12CC3CC(C1)C(NC(=O)C1(CNS(=O)(=O)c4ccc(F)cc4C(F)(F)F)CC1)C(C3)C2 +COc1ccc2cc1Oc1ccc(cc1)CC1c3c(cc(OC)c4c3Oc3cc5c(cc3O4)CCNC5C2)CCN1C +CCC1CN(C(=O)c2cc(C)ccc2-n2nccn2)C(Cc2cccc(-n3nccn3)c2)CO1 +CCCc1nc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)cn1-c1ccc(F)cc1 +NC(=O)c1ccc2[nH]c(-c3ccc(C(O)c4ccc(Cl)c(C(F)(F)F)c4)cc3)nc2c1 +Cc1cccc(-n2c(-c3ccc(S(N)(=O)=O)cc3)coc2=O)c1 +CN1CC(c2csc(N)n2)n2nc(C(=O)NCc3ccc(F)cc3)c(O)c2C1=O +Nc1nccnc1C(=O)Nc1cnccc1N1CCCC(N)C1 +N#Cc1nc(-c2ccnc(Nc3ccc(NC(=O)CN4CCC(F)C4)nc3)n2)ccc1N1CCC(O)C1 +NS(=O)(=O)C(F)(F)c1ccc([N+](=O)[O-])cc1 +Cc1cc(C)c(-n2c[n+](CC(=O)c3ccc4ccccc4c3)c(C)c2C)c(C)c1 +CNC(=O)CN1CCC(c2cc3c(-c4cc(F)ccc4OC)ccnc3[nH]2)CC1 +Cn1c(CNc2ccnc3cc(Cl)ccc23)nc(-c2ccccc2)c1CN1CCCC1 +Cc1nn(C)c(C)c1N(CC(F)F)S(=O)(=O)c1c(Cl)cc(CCCOC2CCN(C)CC2)cc1Cl +CN(C)Cc1nc2c(sc3ccc(-c4ccc(OC(F)(F)F)cc4)cc32)c(=O)[nH]1 +COCC(C)Oc1cc(C#Cc2cccc(N)c2)cc(C(=O)Nc2ccn(C)n2)c1 +O=C(NCCCN1CCN(c2cccc(Cl)c2)CC1)c1nc(-c2cccnc2)no1 +CCCCNC(=O)CC(O)C(Cc1ccccc1)NC(=O)C(NC(=O)c1ccc(OC)cc1OC)C(C)CC +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(Cc2ccc(-c3ccccc3)cc2)CC1 +CCS(=O)(=O)N1CCN(C(=O)C(Cc2cccc(C(=N)N)c2)NS(=O)(=O)c2ccc3ccccc3c2)CC1 +CN1CCN(CCCN(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)C2CCC3(c4ccc(F)c(C#N)c4)CC23)CC1 +CC1(C)c2cc(N3CCN(C4CCC4)CC3)c(C3CC3)cc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +Cc1c(C(=O)NC(CCCNC(=N)N)C(=O)O)nc(C(c2ccccc2)c2ccccc2)n1C +COC(=O)Nc1ccc2c(c1)NC(=O)CC(C)C=CCC(NC(=O)c1c(F)cc(C)cc1F)c1nc-2c(Cl)[nH]1 +O=C(O)C1CC(N=C(S)Nc2ccccc2)c2c(Cl)cc(Cl)cc2N1 +CC(C)CC(N)CN(C(=O)C(C)Cc1ccccc1)c1ccc(-c2ccccc2)cc1 +COc1ccc(C=CC(=O)c2ccc(OC)c3c2OC(C)(C)C=C3)cc1OC(=O)Cc1ccc(Cl)c(Cl)c1 +O=[N+]([O-])c1cccc(C(=NNC(=S)Nc2ccccc2)c2ccccn2)c1 +CC(C)C1CC(O)=C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)C(=O)N1Cc1ccc(F)cc1 +O=C(NO)c1cnc(NC2c3ccccc3-c3ccccc32)nc1 +CNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(OCCCN5CCOCC5)c(C(F)(F)F)c4)ccc3C)CC2)ncn1 +CC(=O)N1CCN(c2nc(C#N)nc(NCC(C)C)c2N)CC1 +CC(=O)Nc1cc(-c2c(-c3ccc(F)cc3)nc(SCC(=O)N(C)C)n2C)ccn1 +CCC(=C(c1ccccc1)c1ccc(OC(C)=O)cc1)c1ccc(S(C)(=O)=O)cc1 +OC1CNC(CNC(COCc2ccccc2)c2ccccc2)C1O +CCCc1cnc(N2CCC(Oc3cc(=O)n(-c4ccc(N5CCC(O)C5=O)c(C)n4)cc3Cl)CC2)nc1 +Cn1nc(C(C)(C)C)cc1NC(=O)c1cc(Cl)cc(Nc2ncnc3cnc(N4CCOCC4)nc23)c1 +N#Cc1ncc(Nc2cc3cccc(Cl)c3cn2)nc1OCC1CCNCC1 +CNC(C)C(=O)NC(C(=O)NC(CCCNC(=N)N[N+](=O)[O-])C(=O)NC1CCCc2ccccc21)C(C)C +N#Cc1cnc2ccc(NCc3ccco3)cc2c1Nc1ccc(F)c(Cl)c1 +COc1ccccc1-c1ccc2c(Cl)cnc(N=C(N)N)c2c1 +CCN(CCNC(=O)C(C)N)Cc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1O +Cc1c(CC(=O)O)c2ccccc2n1C(=O)c1ccc(OCC2CN(C)c3ccccc3O2)cc1 +O=C(NO)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +COc1cc2c(Nc3ccc(Br)c(C)c3)ncnc2cc1OCC1CNCCO1 +O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(OCc2ccccc2Br)cc1 +CC(NC(=O)c1cccc2c1N(Cc1cccc(Cl)c1)CC2)c1ccc(C(=O)O)cc1 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3Cl)nc12)N1CC(O)C1 +CC(=O)NC(C)Cc1ccc(C#Cc2ccnc(N3CCC4(CCCC4)C3)n2)cc1 +CC[Si](CC)(CC)OC1CC(C)CC2C1CC(O[Si](C)(C)C(C)(C)C)C1C(C)(CO)CC(O)CC21C +CCN(CC)c1ccc2cc(-c3nc4ccccc4[nH]3)c(=O)oc2c1 +Nc1ccc(-c2ccccn2)nc1C(=O)Nc1cnccc1N1CCCC(N)C1 +CCC(CC)C(O)C1OC(C(=O)O)=CC(N)C1NC(C)=O +N#Cc1ccccc1-c1cc(-c2ccccn2)cn(-c2ccc(F)nc2)c1=O +CC(C)CC(C[Si](O)(O)CNC(=O)CCc1ccccc1)C(=O)NC(CC(C)C)C(=O)O +COC(=O)C(NC(=O)C(CCCCN)NC(=O)C(CO)NC(=O)Cc1ccc(CCCCn2ccnc2C)cc1)C(=O)O +CN(Cc1ccc(C#N)cc1)Cc1ccc(COc2ccc3cc(C#N)c(=O)oc3c2)cc1 +C=C1C(=CC=C2C(C)CCC3(C)C2CCC3C(C)CCCC(C)(C)O)CC(O)CC1O +CCOc1cccc(NC(=O)c2ccc(OC)c(C(=O)Nc3cccc(OCC)c3)c2)c1 +S=C(NCc1cccc(I)c1)N1CCC(c2c[nH]cn2)CC1 +CCN(C(=O)c1cnc(C(C)(C)C)nc1NCc1ccco1)C1CCCNC1 +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2Cc2ccc(F)cc2)c1 +O=C1c2ccccc2CN1CCC1CCN(CC2COc3ccccc3O2)CC1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(OCCO)c2)c1 +Cc1cc(-c2ccc(C(=O)c3cccc(O)c3)s2)ccc1O +NC(=O)c1cc(CN2C(=O)NC(CCc3ccccc3)C(O)C2Cc2ccccc2)ccc1F +Cc1nc2ccccc2nc1-c1cc2nc(C3=CCCC3)cc(NC3CCOCC3)n2n1 +COc1ccc(C(N)c2nc3ccc(-c4c[nH]nc4C)cc3c(=O)[nH]2)cc1 +C=C(C)CCN1C2CCC1CC(=C(c1ccc(C(=O)NCC)cc1)c1cccc(C(C)=O)c1)C2 +COc1ccccc1N1CCN(CCCCOc2ccc3c(c2)NC(=O)CC3)CC1 +Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4ccncc4)c(Cl)c3)c21 +Cc1ncn(CCC(C(N)=O)(c2ccccc2)c2ccccc2)c1C +CN1CCN(c2cc(C(F)(F)F)ccc2N2CCOc3cc(S(=O)(=O)Nc4nccs4)ccc32)CC1 +COc1cc2nccc(Oc3ccc(NC(=O)N4CCN(c5ccccc5)C4=O)cc3)c2cc1OC +COc1ccc(-c2nnnn2-c2cc(OC)c(OC)c(OC)c2)c(O)c1O +CC1(CCC(=O)O)CC(=O)c2ccc(OCc3cccc(OCc4ccc5ccccc5n4)c3)cc2O1 +OCc1cc(Cl)c(Nc2nc3c(Nc4ccc(C(F)(F)F)cc4)ncnc3s2)c(Cl)c1 +O=C(Nc1cnccc1N1CCNCC1)c1csc(N2Cc3ccccc3C2)n1 +Cc1cc(CCC#N)cc(C)c1Oc1cc(Nc2ccc(C#N)cc2)c(N)cc1C(F)(F)F +CC(C)S(=O)(=O)n1c(N)nc2ccc(-c3[nH]c(-c4c(Cl)cccc4Cl)nc3-c3ccc(F)cc3)cc21 +Nc1nc(N)c(-c2ccc(NCc3cc(F)c(S(=O)(=O)C(F)(F)F)c(F)c3)cc2)c(COCc2ccccc2)n1 +Cc1cc(C(=O)Nc2ccc(N3CCCC3=O)cc2F)n(-c2cc3ccccc3cc2S(C)(=O)=O)n1 +NS(=O)(=O)c1ccc(NCc2cc(Br)cc(Br)c2O)cc1 +COc1ccc(-n2nc3c(NC(=O)NCc4ccccc4)nc4ccccc4n3c2=O)cc1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CC(NC(=O)c2cccnc2O)c2ccccc2)CC1 +NC(=O)c1cnc(NC2CCCCC2)c2c1[nH]c1cccc(Cl)c12 +COc1nc(Oc2cccc(Cl)c2C)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CCC1(CC(O)(CNC(=O)c2cnn(-c3ccc(F)cc3)c2N)C(F)(F)F)CCCc2ccccc21 +CC(C)c1cc2c(cc1NC1CNC1)N1C(=NNC(=O)C1C)CO2 +O=C(Nc1cnccc1OC1CCNCC1)c1csc(-c2c(F)cccc2F)n1 +COc1ccccc1CCNCc1cccc(CCNCC(O)c2ccc(O)c3[nH]c(=O)sc23)c1 +CC(C)OCCCNC(=O)c1cccc(C(O)(c2ccc(Cl)cc2)c2cccnc2)c1 +CCOCCOCCOc1ccc(Cc2cn(C3OCC(O)C(O)C3O)c3cccc(Cl)c23)cc1 +CCCCN(CC)c1nc(C)nc2c1nc(C(F)(F)F)n2-c1ccc(C(C)C)cc1Br +CC(C)(Sc1ccc2c(c1)CC(NC(=O)Nc1ccc(OC(F)(F)F)cc1)C2)C(=O)O +O=C1CCC(C=CC(O)Cc2ccccc2)N1CCCCSc1nn[nH]n1 +CC(C)(C)C(NC(=O)C(CC1CCCC1)CN(O)C=O)C(=O)N1CCC(NCc2cc(F)c(F)cc2F)CC1 +Nc1nccc(-c2ccc3nc(C4COc5ccc(C(=O)NC6CC6)cc5C4)[nH]c3c2)n1 +CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(N(C)C)cc4)cc3)nc2n(CCCOC)c1=O +COc1ccc(C2=NN(CCCCOc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)C3CC=CCC23)cc1Cl +CC(C)S(=O)(=O)N1CCC(N2CCC(Oc3ccc(S(=O)(=O)c4ccc5c(c4)OCO5)cc3)CC2)CC1 +CC(=O)N1CC2CC1CN2Cc1cc2ccc(Oc3nc4ncccc4s3)cc2o1 +CCN(NC(=O)c1cc(OC)no1)C(=O)NCc1ncc(-c2cc(Cl)cc(F)c2-c2nnn(C)n2)cc1F +CCc1ccc(-c2cc3cn(C4CC(O)C(CO)O4)c(=O)nc3s2)cc1 +O=[N+]([O-])c1cccc(-c2nc(-c3ccco3)cc3cccnc23)c1 +ON=C1CCc2cc(Nc3c(-c4ccccc4)nc4cnccn34)ccc21 +O=c1[nH]c2c(O)ccc(C(O)CNCCc3ccc(CN4CCCC4)cc3)c2s1 +N#Cc1ccc(Cn2cncc2CNC2CCN(C(=O)c3cccnc3N)C2)cc1 +Cc1nnc(Cl)c2nn(-c3ccc(Cl)cc3)c(C)c12 +CCCCCOc1cnc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)s1 +COC(=O)c1cc2c3ccccc3n(C(C)=O)c2cn1 +c1c[nH]c(CN2CCN(CCCc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)n1 +Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3cccc(C)c3F)c2)s1 +CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(=O)O +NCCCCCNCc1ccc(OC2=CC(=O)c3ccccc3C2=O)cc1 +CN(C)C(=O)n1nnc(-c2ccc(-n3cccn3)cc2)n1 +COc1cc(OC)cc(N(CCN2CCNCC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(Nc2ccc(CCC(=O)NCCCN3CCCC3)cc2)n1 +CCn1nnc(C2OC(n3cnc4c(NC)ncnc43)C(O)C2O)n1 +COc1cc2ccc(C(C(C)C)n3ncnn3)cc2cc1OC +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N(C)C4CCCC4)c3)C2)cc1 +CNS(=O)(=O)N(C)C1CCN2CCc3ccccc3C2C1 +O=c1c(C(c2cccs2)c2c(O)oc3ccccc3c2=O)c(O)oc2ccccc12 +Cc1ccc(-c2c(CN)c(CC(C)C)nc3ccc(N4CC(=O)NCC4=O)cc23)cc1 +Cc1nnc(C(=O)COc2ccc(OCc3ccccc3)cc2)o1 +Cc1ccc(C(O)c2cccc(C(C#N)=C(N)Sc3ccccc3N)c2)cc1 +COc1cccc(SCCOc2ccc(CC(Nc3ccccc3C(=O)c3ccccc3)C(=O)O)cc2)n1 +O=C(Nc1ccc(C(=O)N2CCCc3c[nH]c4cccc2c34)cc1)c1ccccc1-c1ccccc1 +CC(C)n1c(C#CP(=O)(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c2ccccc21 +NS(=O)(=O)c1ccc(N=Nc2cnc(O)c(O)c2)cc1 +CC1(CCC2CCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21 +Cn1cc(C=C2Oc3ccc(NC(=O)Nc4cccnc4)cc3C2=O)c2c(N3CCOCC3)ccnc21 +CCCCCCCn1cc(C)c2ccc(C(=O)Nc3c(Cl)cncc3Cl)cc21 +O=C(O)C(Cc1ccc(N2C(=O)CCC(c3ccccc3)C2=O)cc1)NC(=O)C1CCC(=O)N1Cc1ccccc1 +N#Cc1ccc(CCOC(=O)N2CCN(CCCc3ccccc3)CC2)cc1 +O=C(C1C=C2c3cccc4[nH]cc(c34)CC2N(C(=O)Nc2ccsc2)C1)N1CCCC1 +COC12C=CC3(CC14CCCC4O)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +Cc1ccc(-n2nc(N3CCN(CC(C)C)CC3)cc2NC(=O)c2cnn3cccnc23)nc1 +O=C(NC1c2ccccc2CCC1c1cccc(O)c1)C(c1ccccc1)c1ccccc1 +CCOC(=O)c1c(-c2ccccc2)oc2ccc(OC(C)C(=O)O)cc12 +CCCCC1c2ccccc2C=NN1C(=O)C=Cc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(Nc2ccc(CCC(=O)NCCN3CCCCC3)cc2)n1 +COc1cc(OC)c2ccn(S(=O)(=O)c3ccc(N)cc3)c2c1 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2nc(-c3cnc4ccccc4c3)cs2)cc1 +C=CCC(O)(CC=C)C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +CCc1ccc(Cc2cc3c(cc2Cl)OC2(C3)OC(CO)C(O)C(O)C2O)cc1 +CC#CCC(C)C(O)C=CC1C(O)CC2(CCC#CCCCO)CC(=CCCCC(=O)O)CC12 +N#Cc1cnc2c(Cl)cc(NCCc3c[nH]cn3)cc2c1Nc1ccc(F)c(Cl)c1 +Cc1c(-c2ccncc2)nnc(N2CCN(c3cnc(C(C)(C)O)cn3)C(C)C2)c1C +COc1ccc(CC(NC(=O)OCc2ccccc2)C(=O)NCC#N)cc1 +CC(C)c1cc(C(=O)N2Cc3ccc(C(=O)N4CCN(C)CC4)cc3C2)c(O)cc1O +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ccc(CCCN)cc3)cc2N=C(N)C1 +OC(CF)CN1c2cccc(-c3cccc(OC(F)(F)F)c3)c2CCC1c1cccc(OC(F)(F)F)c1 +CNS(=O)(=O)c1ccc(Oc2cc(C(=O)Nc3cnc(C)cn3)cc3nn(C)cc23)cc1 +Fc1cccc(COc2ccc(Nc3ncnc4sc(-c5ccc(CNCc6ccccc6)o5)cc34)cc2Cl)c1 +CNCCCn1cc(C2=C(c3coc4ccccc34)C(=O)NC2=O)c2cc(Br)ccc21 +Nc1cccc(C(=O)c2ccc3c(C=Nn4cccc4)n[nH]c3c2)c1 +C(=Cc1ccccc1)CN1C2CCC1c1c([nH]c3ccccc13)C2 +CCCCCN(CC(O)C(Cc1ccccc1)NC(=O)OCCN1CCNC1=O)S(=O)(=O)c1ccc(OC)cc1 +Nc1ccccc1NC(=O)c1ccc(CSC2=NC(Cc3ccccc3)CS2)cc1 +CC(C)(C)C(COc1ccc(C(F)(F)F)cc1C(=O)N=c1sc(C(C)(C)C)cn1CC1CCCO1)=NO +O=C(Nc1ccc(Cl)cc1)c1nnnn1CCc1ccncc1 +COC(=O)C1(Cc2ccc(OCc3cc(C)nc4ccccc34)cc2)CC1C(=O)NO +COc1cc(CNC(=S)NC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)c(Cl)cc1O +CS(=O)(=O)Nc1ccc(OCCNCCNc2ccc(Cl)c(Cl)c2)cc1 +O=C(O)CC(NC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1)c1cnc2ccccc2c1 +CNC(=O)OCc1c(COC(=O)NC)c(-c2ccc(OC)cc2)n2c1Cc1cc(OC)ccc1-2 +Nc1ncc(-c2ccc[nH]2)cc1C(=O)Nc1ccncc1 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)CNCc4ccccc4)cc13)N(C)S(=O)(=O)CC2 +CS(=O)(=O)c1ccc(Cl)cc1Cn1cc(Cl)cc(C(N)=O)c1=N +CN1CCCC(n2cc(S(=O)(=O)c3cccc(F)c3)c3cccnc32)C1 +OCC12COC(c3ccc(Cl)c(Cc4ccc(O)cc4)c3)(O1)C(O)C(O)C2O +N#CC1CCCN1C(=O)C(N)Cc1ccc([N+](=O)[O-])cc1 +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCC(C(N)=O)CC4)ccc3OCC)nc12 +Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)Nc4ccc(NS(C)(=O)=O)cc4)cc3)c2)o1 +CCCCCCCCOC(=O)C1=C(c2ccccc2)CCN(CC)C1 +O=C(NCc1ccc(F)cc1)c1cn2c(c(O)c1=O)C(=O)N1CCOC1C2 +C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C4CC4)nc(C)n3)CC2)c2cc[nH]c2c1=O +O=C(CBr)NCCc1c(-c2ccccc2)[nH]c2ccccc12 +CN1CCN(CCC(=O)NS(=O)(=O)c2ccc(Nc3nc(N)n(C(=O)c4c(F)cccc4F)n3)cc2)CC1 +Cc1nnc(C2CC(S(=O)(=O)c3ccccc3Cl)CN2c2ccnc(C#N)n2)o1 +Cc1ccc(S(=O)(=O)NCCCCOc2ccc(Cc3cnc(N)nc3N)cc2)cc1 +O=C(CC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1)NC(c1ccncc1)c1ccc(Cl)cc1 +COc1cccc(CNC(=O)c2nc3scc(C)c3c(=O)[nH]2)c1 +O=C(CCN1CCCC1)Nc1ccc2c(c1)C(=O)c1cccc3ccnc-2c13 +N#Cc1ncc2nc1OCCC=CCOc1ccccc1NC(=O)N2 +CCCc1c(OCCCOc2cc(NC(=O)c3nn[nH]n3)c(C)cc2Cl)ccc(C(C)=O)c1O +CN(C)c1nc(-c2ccc(N3CCOCC3)cc2)cc2ncn(C)c(=O)c12 +CCCNc1c(C)nc(-c2c(C)cc(C)cc2OC)c2ccccc12 +COc1ccccc1NC(=O)N1CCNCC1COc1cccnc1 +NC(=O)c1nc(Nc2cccc3ncccc23)sc1NC(=O)c1ccsc1 +CC(C)(C)N=C(NC#N)Nc1cccc(C(=CCCC(=O)O)c2cccnc2)c1 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+COc1cc(OC)cc(N(CCCN2CCCC2=O)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +COc1cc2c(=O)c(-c3cc(OC)c4c(c3OC)OCO4)coc2cc1OCc1ccccc1 +OC1CCN(c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)C1 +O=C(C(=O)N1CCCCC1)c1c(-c2ccccc2)[nH]c2ccccc12 +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)F)C(C)C +Cc1c(Nc2ccc(I)cc2F)c2c(=O)[nH]cnc2n(C)c1=O +CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3COCc3ccccc3)cc2)cc1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc4cc(NC(=O)c5ccccc5)ccc4n3)C12 +CCCCC(C)(O)C1CCCC2=Cc3c(-c4ccc(F)cc4)ncn3CC21C +NC(=O)c1cnc(N2CCC3(CC2)CCN(Cc2cccc(C(F)(F)F)c2)c2ccccc2O3)s1 +CC1=NCCc2cc(Cl)c(O)cc2N1c1ccc(C)cc1 +O=C(Nc1ccn(S(=O)(=O)c2ccc(Cl)nc2)c1)c1ccccn1 +CCC(CC)(c1ccc(OCC(O)C(C)(C)C)c(C)c1)c1ccc(OC(CCO)CCO)c(C)c1 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cccc(O)c23)C1(C)C +O=C(NCc1cccc(-c2cccc(-c3cc4c[nH]ccc-4n3)c2O)c1)Nc1ccccc1Cl +CC(=O)Nc1ccc(OC(=O)CNC(=O)C(C)c2ccc(Nc3ccnc(C(F)(F)F)c3)cc2)cc1 +CC(=NNC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1)c1ccccc1O +CCNS(=O)(=O)c1ccc(NC2CC3CCC2C3)c(NCc2ccncc2)c1 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+CC(NC(=O)COc1nc2cccnc2n1Cc1ccc(F)cc1)c1ccc(F)cc1 +CS(=O)(=O)N(Cc1ccc(F)c(F)c1)c1cc2ccccc2s1 +COCCNC(=O)c1ccc2c(-c3ccc(C#N)cc3)n[nH]c2c1 +O=c1[nH]c(=O)c2c(CCC3CCC3)cc(=O)oc2[nH]1 +Cc1cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)ccc1OCCO +COc1cc(C(=O)NC2CCN(CC(N)=O)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +Cc1cc(Nc2nccc(-n3ccnc3-c3ccccc3)n2)ccn1 +O=c1nc2oc(-c3ccccc3)cc2cn1C1CC(O)C(CO)O1 +CCCCc1c(C)n(C(=O)N2CCC(C)CC2)oc1=O +N#CC(Cc1ccc(-c2cnc3n2CCC3)cc1F)NC(=O)C1NC2CCC1C2 +COc1ccc2c(S(=O)(=O)c3ccccc3)cn(CCN(C)C)c2c1 +COC(=O)c1ccc(N(Cc2ccccc2)c2cc(C(=O)N3CCCC3)n(C)c2)cc1 +Nc1ncc(-c2nc(N3CC4CCC(C3)O4)c3sccc3n2)cn1 +O=C(NCCN1CCN(c2ccccc2)CC1)c1cnc2ccccc2n1 +Cc1cc(F)cc(NC(C)c2cc(C(=O)N(C)C)cc3c(=O)cc(N4CCOCC4)oc23)c1 +COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)ccc1F +CN1CCN(CCCn2c3ccc(O)cc3c3c4c(c(-c5c(Cl)cccc5Cl)cc32)C(=O)NC4=O)CC1 +CCNC(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(N(CCN(C)C)S(C)(=O)=O)cc1)c1ccccc1 +NC(=O)Nc1ccc(-c2ccc(S(=O)(=O)C(F)(F)F)cc2)cc1 +CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(C(F)(F)S(C)(=O)=O)o4)c(C(C)C)c23)c(F)cc1F +COc1cccc(C2CCC(N3CCN(c4ccccn4)CC3)CC2)c1 +Cc1nc2ccccc2n1Cc1nc2c(O)cccc2[nH]1 +CCN(CC)CCCNc1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(-c3ccccc3)no2)n1 +C=CC(=O)N1CCC(Oc2cc3c(Nc4ccc(Cl)c(Cl)c4F)ncnc3cc2OC)CC1C(N)=O +COc1ccc(-c2c(CO)c(CO)cc3ccc4c(c23)OCO4)cc1O +ClC(Cn1ncc2c(Nc3ccccc3)nc(SC3CCCC3)nc21)c1ccccc1 +C1=C(c2c[nH]c3ccccc23)CCN(Cc2ccccc2)C1 +C=CCn1nc(C(=O)N2CCCC2)c2c1CCC(N1CCCCCC1)C2 +CCC(C)C(=O)N1CC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)C1 +O=C(NNC(=O)C1CCC(CNS(=O)(=O)c2cccs2)CC1)c1cccs1 +CCCCN(CCCC)CCCNc1nc(Nc2cccc(C(F)(F)F)c2)c2ccccc2n1 +CCCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NCc2ccc3ncsc3c2)C(C)C)nn1 +CC1CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1C +CC1CCC(Cn2c(N3CCCC4CCCC43)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +N=C(N)NCCCOc1ccc(CC(NS(=O)(=O)c2cccc(C(F)(F)F)c2)C(=O)O)cc1N +COc1cccc(CO)c1-c1cccc(C(CC(=O)O)c2nnc(C)o2)c1 +Nc1c2c(nc3c1C(c1cccs1)c1c(c4ccccc4oc1=O)O3)CCCC2 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+CCCN(CC1CC1)C(=O)c1c(C(F)(F)F)nc2n(-c3c(C)cc(C)cc3C)c(Cl)cn12 +O=C(NCC(CCNC1CCCC1)c1ccc(-c2cccnc2)cc1)Nc1cc(Cl)cc(Cl)c1 +CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1nc3ccc(Cl)nc3s1)c1c(O)ccc(F)c12 +Cc1ccccc1CNC(=O)c1nc(-c2ccc(F)cc2)n(CCC(O)CC(O)CC(=O)O)c1C1CC1 +COc1ncc(Cc2cn(CC(=O)N(C)Cc3ccc(-c4ccc(F)cc4)cc3)c(SCc3ccc(F)cc3)nc2=O)cn1 +CC(Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(Cl)c12)C(F)(F)F +C=C1C(=O)OC23CCC4C(C)(COC(C)=O)CCCC4(C)C2CCC1(O)C3 +COc1ccc(Nc2ccc(NC(=O)c3cccc(Cc4n[nH]c(=O)c5c4CCCC5)c3)cc2)cc1 +CC1(C)CC(=O)C(C2C3=C(CC(C)(C)CC3=O)Oc3cc(Cl)ccc32)=C(O)C1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(F)c(Cl)c4)cn3CCN3CCCC3)CC2)c1Br +CCONC(=O)c1ccc(C)c(Nc2ncnn3cc(C(=O)OC)c(C)c23)c1 +Cc1cn2ccnc(Nc3ccc(F)c(C4(C(F)F)COCC(N)=N4)c3)c2n1 +Cn1c(=O)c2c(nc(C=Cc3ccc(Cl)c(Cl)c3)n2C)n(C)c1=O +COc1ccc(N(C)c2nc(NN)nc3ccccc23)cc1 +CN(C)c1nc(Cl)nc2c1ncn2Cc1ccc(C(C)(C)C)cc1 +O=C(Nc1ccccc1Cl)c1c(NC(=O)C(F)(F)F)sc2c1CCCCC2 +CC(C)C(N)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 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+Fc1ccc(CC2(c3ccc4[nH]ccc4c3)CCNC2)cc1 +CCCCNC(=O)C1CCCC1C(O)C(CC(C)C)NC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(C)=O +O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CN(C2CCCCC2)C1 +CCOc1ccc(C2=NN(c3ccc(C4=NNC(=O)CC4C)cc3)C(=O)C3CC=CCC23)cc1OCC +CC(=O)C(=Nc1cccc(Cl)c1)NNc1ccccc1[N+](=O)[O-] +COc1ccccc1NC(=O)NC(C(=O)N(CC(=O)NO)CC1CCCC1)C(C)(C)C +NC(=O)C1CCCN(C(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)C1 +Cc1cc(C)[n+](CCc2ccc(S(N)(=O)=O)cc2)c(C)c1 +O=C(O)CSc1cc(C(=O)c2ccccc2O)cn2c(=O)c3c4c(sc3nc12)CCCC4 +N=C1Sc2cc(-c3cc4ccccc4o3)ccc2C2=NCCCN12 +O=C(Cc1ccccc1)Nc1nc2nn(CCc3ccccc3)cc2c2nc(-c3ccc(-c4ccco4)cc3)nn12 +CN1C(=O)C(NC(=O)c2cc3cc(C(F)(F)F)ccc3[nH]2)Cc2ccccc21 +NC(C(=O)N1CCSC1)C1CCC(NC(=O)c2ccc(F)c(F)c2)CC1 +COc1cc(OC)nc(Oc2cccc(OC)c2C(=O)O)n1 +C=C1OC(CC)=NC12CCC1C3CCC4=CC(=O)CCC4=C3C(c3ccc(C(C)=O)cc3)CC12C +COc1ccc(NC(=O)c2cc3cc(C4(O)CCN(CC(C)(C)C)CC4)ccc3o2)cc1OC +Oc1ccc(-c2cc(-c3ccccn3)cc(-c3cccc(O)c3)n2)cc1 +O=C(C=C(c1ccccc1)c1ccccc1)NCCCCc1cccnc1 +CCc1nc2c(-c3ccc(Cl)cc3Cl)ccnc2n1C(C)C1CCC1 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+O=C(NCc1cccnc1)c1ccc(N(Cc2ccccc2)Cc2ccccc2Cl)cc1 +Nc1nc(-c2ccccc2)cn2c(=O)n(-c3ccc(O)cc3)nc12 +CC1(O)CC(c2cccc(C(F)(F)F)c2)(C(O)c2ccccn2)C1 +CC(C)CCNCc1ccc(N2CCCc3cc(C(N)=O)ccc32)cc1 +O=c1nc(N2CCOCC2)cc(N(Cc2cccc3ccccc23)CC(O)C(F)(F)F)[nH]1 +NC(CC(=O)N1CCCC1CNS(=O)(=O)c1ccc(Cl)cc1)Cc1ccccc1F +CC(C)NC(=O)Sc1ccccc1C(=O)NC(C)C(N)=O +CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCc1nccc2ccccc12 +Fc1cc(-c2c(F)cccc2F)cc(-n2nnc(-c3ccccn3)n2)c1 +CONC(=O)N(Cc1ccsc1)C1CCN(C(C)CCNC(=O)c2c(C)cc(C(=O)NC(C)C)nc2C)CC1 +O=C(Nc1ccc2c(c1)C=CS(=O)(=O)O2)c1ccccc1 +COc1cc(-c2cn(C3CCc4ccccc4N(CCF)C3=O)nn2)ccc1-n1cnc(C)c1 +O=C1OCC2(O)Nc3c(c4cccnc4c4ncccc34)C(c3cccc(C(F)(F)F)c3)C12 +N=C(NC(=N)N1CCN(C(=N)NC(=N)Nc2ccccc2)CC1)Nc1ccccc1 +CCCCCc1noc(C2CN(CC)CC=C2c2ccccc2)n1 +COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OCCOC)C1c1cnc(SC)n1Nc1ccccc1 +CN1CCC(N(C)C(=O)N2CCC(n3cnc4cc(-c5ccc(C(F)(F)F)cc5)sc4c3=O)C2)C1 +CC(=O)N1c2ncncc2NC2=C(C(=O)CC(C)(C)C2)C1c1ccc(Cl)cc1Cl +COc1ccccc1-c1ccc(CC(NC(=O)C2CCCO2)C(=O)O)cc1 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+CC1C2Cc3cc([N+](=O)[O-])c(C(N)=O)cc3C1(C)CCN2CC1CC1 +Nc1ccc(CNc2nccc(Nc3cc(C4CC4)[nH]n3)n2)cn1 +CCn1nc(CC2CCCCC2)cc1C1CCN(CC2CN(C(C(=O)O)C(C)C)CC2c2cccc(F)c2)CC1 +COC1CCC2(CC1)Cc1ccc(C#CC3CCC3)cc1C21N=C(C)C(N)=N1 +CN(c1ccc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)cc1)c1cccc(F)c1 +Nc1ccccc1Nc1ccc2c(c1)SCc1ccccc1C2=O +COc1cc2nccc(Oc3ccc(NC(=O)c4cc(Cc5ccccc5)cn(-c5ccccc5)c4=O)nc3)c2cc1OC +CC(=O)Nc1cccc(C2CCN(CCCCn3c(-c4ccccc4)nc4ccccc43)CC2)c1 +CN(C)c1cccc2c(S(=O)(=O)NCCCNC3CCC4(CC3)OOC3(O4)C4CC5CC(C4)CC3C5)cccc12 +COc1cccc(OC)c1C(=O)N1C2CCC1C(COc1ccc(F)cn1)C2 +O=S(=O)(NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2)c1c[nH]cn1 +OCC12COC(C(n3cnc4c(NCc5cccc(I)c5)ncnc43)O1)C2O +CNCCn1c(=O)c2cc(OC)c(OC)cc2c2cnc3cc4c(cc3c21)OCO4 +CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(C(=O)NC)n2n1 +O=C(c1ccc(Cl)cc1)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 +CNC(=O)CC(NC1=NS(=O)(=O)C2CCCCC2O1)c1ccccc1 +O=C(O)c1ccc(C(=O)Nc2cc(Nc3cnccn3)nc(-c3ccnc(N4CCNCC4)c3)c2)cc1 +CCCCN(CCCC)c1cc(C)nc2c(-c3c(C)cc(C)cc3Cl)nn(C)c12 +O=C(c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1cnc(N2CCNCC2)nc1)C1CC1 +CSc1nn2cc(-c3nc4ccc(OCc5cc(F)cc(F)c5)cc4o3)nc2s1 +O=C(NC(Cc1ccccc1)C(=O)NC1C(=O)N2CCOC12)OCc1ccccc1 +CCC1CN2CCC34c5ccccc5N5C=C6C7CC8N(CCC89c8ccccc8N(C=C(C1CC23)C54)C69)CC7CC +C=CCNc1nc(N2CCC(NCC3c4ccccc4CCc4ccccc43)CC2)c2ncn(CC=C)c2n1 +CNC(=O)C(NC(=O)C(CCCCOc1cccc(C)c1)CC(=O)NO)C(C)(C)C +CC(C)CNCc1ccc(-c2ccccc2S(=O)(=O)N2CCC(F)(F)C2)cc1 +O=C(NCc1cccc(Cl)c1)C(=O)c1c[nH]c2ccccc12 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(C=CC(N)=O)cccc3nc2-1 +Nc1nc2cc3c(cc2s1)CC1C2CCCCC32CCN1CC1CCC1 +O=C(O)CCC(NC(=O)Sc1cc[n+]([O-])cc1)C(=O)O +CCN1CN(c2ccccc2)C2(CCN(C(c3ccccc3)c3ccccc3)CC2)C1=O +NCCCCC(NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccc2ccccc2c1)NC(=O)c1ccc(CN)s1)C(N)=O +CC(c1ccc2[nH]c(=O)sc2c1)c1ccn(-c2ccccn2)n1 +CCOc1ccc2c(c1)CCN(c1ccc(C(=O)Nc3cccc(C)n3)cn1)C2 +Fc1cccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1F +COc1cccc(N2CCN(C3=Nc4c(F)cccc4C(CC(=O)O)N3c3cc(C(F)(F)F)ccc3OC)CC2)c1 +O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cn2ccnc2)c1 +N=C(N)c1cccc(-n2nc(C(F)(F)F)cc2C(=O)Nc2ccc(-n3cnc4ccccc43)cc2F)c1 +CN(C)CC1CC2c3ccccc3Cc3cccc(Cl)c3N2O1 +COc1ccc(-c2nnc(N3CCN(C(=O)c4ccccc4)CC3)c3ccccc23)cc1 +O=S(=O)(Nc1ccc2nccc(N3CCNCC3)c2c1)c1ccc2c(Cl)cccc2c1 +Cc1nnc2n1-c1sc(C#CCn3c4c(c5ccccc53)CCCCC4)cc1C(c1ccccc1Cl)=NC2 +CNCC(Cc1ccc(O)cc1)N1CCN(CCCC(C)C)CC1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1cccc(OCc2ccccc2)c1 +CN1CCc2cc(O)c(O)c3c2C(C1)CN3c1ccc(F)cc1 +COc1cncc(-c2cc(OC(C)C3CNC(=O)C3)c3cccnc3c2)c1 +CS(=O)(=O)c1ccc2ncc(C(N)=O)c(Nc3cccc(Cl)c3F)c2c1 +Cc1ccccc1-c1cc(-c2ccoc2)cc(-c2ccc(Cl)s2)n1 +CCN(CCC(=O)NCCNc1c2c(nc3ccccc13)CCCC2)C1CCCCC1 +N=C(NCCCOc1ccc(F)cc1)Nc1ccc(C(F)(F)F)cc1 +Cc1cc(NCc2cnc3nc(N)nc(N)c3c2C)c(Cl)cc1F +CN(C)CCCc1cc(Cl)cc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 +O=C(c1ccccc1)c1c[nH]c2nncc-2c1OC1CCCCC1 +COc1ccccc1N1CCN(CCCCNS(=O)(=O)c2cccc3cccnc23)CC1 +CN1Cc2c(NC(=O)NC3CC(CF)(CF)Oc4cc(Cl)ccc43)cccc2N(C)C1=O +COc1ccc(-c2csc(NC(=O)C3CSCCN3S(=O)(=O)c3ccc(C)cc3)n2)cc1 +c1cnc2c(c1)ncn2-c1ccc2[nH]cc(CC3CCCN3)c2c1 +CC(c1ccc(C(F)(F)F)cc1)n1c2c(c3cc(F)cc(S(C)(=O)=O)c31)CCCC2CC(=O)O +CN(C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)C1CCN(C(=O)N(C)C2CCNC2)C1 +CC1(C)C=C(c2cccc[n+]2[O-])c2cc(C(F)(F)C(F)(F)F)ccc2C1=O +CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2Cc2c(C)noc2C)n1Cc1ccc(C(=O)OC)cc1 +Cc1ccc2[nH]c(-c3ccc(Cn4nc(C)c(CC(=O)O)c4C)c(F)c3)nc2c1 +c1cc2[nH]nc(-c3ccc4c(c3)OCO4)c2cc1-c1nnn[nH]1 +Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)C3CCC(F)(F)C3)CC2)n1 +CC(C)(C)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)NO +CC(OC1CN2C(=O)C=CCC2C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(C(N)=O)nc3)nc2n1 +CC(N)P(=O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(N)=O +CCOc1ccccc1-c1cc(C(=O)NCc2ncccc2C)nc(N)n1 +CCCc1cc(C(=O)c2ccc(F)cc2)ccc1OCCCOc1ccc2c(ccn2CC(=O)O)c1 +CC1(O)C(O)C(CO)OC1n1cnc2c(=O)[nH]c(N)nc21 +COc1cc(-c2ccc3c(c2)NC(=O)C3=Cc2ccc[nH]2)ccc1O +CCCC1(O)CCOC(C(=O)NC(Cc2ccccc2)C(O)CN(CC(C)C)S(=O)(=O)c2ccc(OC)cc2)C1 +CCOc1nccc(Br)c1C(=O)N1C2CCC1C(COc1ccccn1)C2 +CN(C)CCCON=C1c2ccccc2-c2nc3c(C(=O)NCCN4CCCC4)cccc3nc21 +CC(C)(C)OC(=O)N1CC2CC(Oc3ncnc(Nc4ccc(S(C)(=O)=O)cc4F)c3[N+](=O)[O-])C1C2 +CC(=O)N1CCN(C2CCC(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 +O=CC(Cc1ccccc1)NC(=O)C1CCCN1S(=O)(=O)c1ccccc1 +CC(CC(=O)OCC1(CO)CC(=Cc2ccccc2C(F)(F)F)C(=O)O1)CC(C)(C)C +COC(=O)c1cccc2c1c(C(=O)c1ccc(Cn3c(C)nc4cccnc43)cc1)cn2C(=O)N(C)C +C#Cc1cc2c(cc1N1CCN(C3CCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CCCN(CCC)Cc1ccc(-c2ccc(CN3CCCCC3)cc2)cc1 +O=C(Nc1ccc(CC2CCC(C(O)c3cccnc3)N2)cc1)C1CCc2scnc21 +CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(F)cc2)c1=O +CCCCOC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 +O=C(Cc1ccc(Cl)cc1)NCc1ccc(-c2nc(C(=O)N3CCCCC3)co2)cc1 +CC(F)(F)c1cccc(NC(=O)Nc2ccc(Oc3cc(NC(=O)C4CC4)ncn3)c(F)c2)c1 +NC(=O)OC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(CC(O)C(F)(F)F)c1=O)c1cccc(Cl)c1Cl +CN(CCCNc1ccnc2cc(Cl)ccc12)Cc1cc(=O)c(OCc2ccccc2)cn1C +CCC(=O)CCCCCC1NC(=O)C2CCCN2C(=O)CC(CC(C)C)NC(=O)C(Cc2c[nH]c3ccccc23)NC1=O +Cc1ccsc1C(=CCCN1CCCC(C(=O)O)C1)c1sccc1C +Oc1ccc2c3c1OC1c4c(c5c(n4Cc4ccccc4)CCCC5)CC4(O)C(C2)N(CC2CC2)CCC314 +Cc1cc(SCC(COc2ccc(C(F)(F)F)cc2)OCc2ccccc2)ccc1OCC(=O)O +NS(=O)(=O)c1ccc(-n2c(S)nc3c(F)cccc3c2=O)cc1 +c1cnn2ncc(-c3ccnc(Nc4ccc5c(c4)OCCO5)n3)c2c1 +COc1cc2c(ccc3c(CCN(C)C)c(Br)c(O)c(OC)c32)cc1O +CNC(=O)C(C)(C(=O)NO)N(C)C(=O)c1ccc(C#Cc2ccc(CNC3CC3)cc2)cc1 +O=C(O)Cn1c(=O)c(C=Cc2ccc(O)c(O)c2)nc2cc(Br)cnc21 +CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc3ccc(NC(=O)NCCC)cc3c2=O)cc1 +c1cc(OCc2ccc3ccccc3n2)cc(OCc2nn[nH]n2)c1 +c1ccc(-c2nc(-c3ccccc3)c3nc(C4CCCC4)nc-3[nH]2)cc1 +N#Cc1ccc(S(=O)(=O)N2CCC(O)(COc3ccc(C#N)c(F)c3)CC2)c(C#N)c1 +Cc1ccc(NC(=O)CCc2nnc(CCC3CCCCC3)n2C2CC2(F)F)c(C)c1 +COc1ccc(-c2nc(N3CCOCC3)c3nc(CN(C)c4ncc(C(=O)NO)cn4)n(C(C)C)c3n2)cn1 +CN1CCN(c2ccc(-n3cc(-c4ccncc4OCC4CCNCC4)cn3)cc2)CC1 +CC(C)c1nc(N2CCN(c3ncc(OCc4ccncc4C#N)cn3)C(C)C2)no1 +CCCN1CC=C(c2c[nH]c3ccc(OC)cc23)CC1 +COc1cc(OCc2cccc(OCc3ccc(F)cc3C(F)(F)F)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(c1nccs1)c1nc(NCc2cccnc2)nc2ccsc12 +COc1ccc(C)n2nc(CCc3c[nH]c(-c4ccccc4)n3)nc12 +CCCCCCN=c1ccn(Cc2ccccc2Cl)c2cc(Cl)ccc12 +CN(C(=O)N1CCC(n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)C1)C1CCN(C2CCC(C)(C)CC2)C1 +CN(C)C(=O)c1ccc(N(Cc2ccc(F)cc2)C(=O)c2cc(Cl)c(O)cc2O)cc1 +Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1ccc(CCCCCCn2ccnc2)cc1 +CCCCCCNC(=O)NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Oc1ccc(C)cc1 +CCn1c(=O)n(-c2cnn(Cc3c(C)noc3C)c2)c(=O)n1Cc1ccccc1 +CC(Sc1cc(-c2cnn(C)c2)cnc1N)c1c(Cl)ccc(F)c1Cl +CC(Nc1c(-c2c(F)cc(OCCCCO)cc2F)c(Cl)nc2ncnn12)C(F)(F)F +O=C(NC(CCc1ccccc1)C(=O)c1ncco1)C(CC(=O)N1CCOCC1)CC1CCCCC1 +N#Cc1ccc2[nH]cc(C3CCC(N4CCN(c5cccc6[nH]ccc56)CC4)CC3)c2c1 +COc1cc(C)cc(-c2ccc(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)c(OC)c2)c1 +COc1ccc(Cc2cnc(N)nc2N)cc1OS(C)(=O)=O +C#CCOCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(C)=O)c1 +CN1CCC(N(C)C(=O)c2cn(C)c(=O)c3[nH]ccc23)CC1 +CS(=O)(=O)CCCCC1(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)CCCC1 +Cc1ccc(C=CC(=O)O)c(OCCC2(C)CCc3c(C)c(O)c(C)c(C)c3O2)c1 +CC(C)CCOc1c(C(=O)c2ccccc2)c[nH]c2nncc1-2 +Cc1ccn(-c2cc(Cl)ccc2C(Oc2cc(N3CC4CCC(C3)N4CC(N)C(=O)O)nc(N)n2)C(F)(F)F)n1 +O=C(O)CCC1(O)OC2=CC(=O)c3c(O)cc(O)cc3C2=C1c1ccccc1 +Cn1ccnc1CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5ccccn5)n4)ccc3[nH]2)CC1 +CCCCC(OCC(O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 +CCc1nc(-c2ccc(Cl)cc2Cl)c(OC)nc1NC(CC)CC +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1ccc(F)cc1C(=O)N1CCCCC1)O2)C(C)=CC(C)(C)N3 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ncc(C(O)(C(N)=O)C(F)(F)F)s1 +COc1ccc(-c2cc(F)cc(C(CC(=O)O)c3ncc(C)s3)c2)c(OC)c1 +CCCCCCCCCCCCCCCCOCCCOP(=O)(O)COCCn1cc(F)c(N)nc1=O +O=C(CCCC(F)(F)F)N1CCC(c2nc(-c3nccs3)no2)CC1 +O=C(COc1ccccc1)Nc1ccc2ncn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2c1 +COC(=O)N1CCC(O)(C#Cc2cccc(C)c2)CC12CCC2 +O=C1CN2Cc3cc(OCCCC(=O)N4CCCC4)ccc3N=C2N1 +CCc1cc(NC2CCN(C(=O)CCNCC(=O)O)CC2)nc(NCc2cn(CCCNCCCNC3CCCCC3)nn2)n1 +Nc1ccccc1NC(=O)c1ccc(C(=O)Nc2cccc(Nc3ncc(-c4cccnc4)s3)c2)s1 +CS(=O)(=O)c1ccc(-c2c(-c3ccccc3)sc3ncnn23)cc1 +COc1ccc(NCc2nc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)[nH]2)cc1 +CC(C)(C)CC(=O)Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CC1(C)N=C(N)N=C(N)N1c1cccc(OCc2ccc(C(N)=O)cc2)c1 +CCc1c(Nc2ccc(S(C)(=O)=O)nc2C)ncnc1OC1CCN(C(=O)OC(C)C)CC1 +Cc1c[nH]c2c(Nc3nc(NC4CCCCC4N)nnc3C(N)=O)cc(F)cc12 +CS(=O)(=O)N1CCC(C(=O)N(CCCN2CCC(Cc3ccc(C(N)=O)cc3)CC2)c2ccc(Cl)c(Cl)c2)CC1 +COc1ccccc1N1CCN(CCCNC(=O)c2ccncc2)CC1 +Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)c1CO +CCc1n[nH]c(CC)c1CC(=O)NCc1ccc(F)c(F)c1F +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)NC(C)C)c1ccc(C(F)(F)F)o1 +CCCCCCCCCCCCCCCCCNC(=O)OCCSCCOC(=O)N(Cc1cccc[n+]1CC)C(C)=O +CS(=O)(=O)N1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +CCN(CCCCCCNc1c2c(nc3ccccc13)CCCC2)CC(=O)Nc1nc(-c2ccccc2)cs1 +O=C(C=Cc1c2ccccc2c(Br)c2ccccc12)N1CCOCC1 +Cc1nc(Nc2cc(C(F)(F)F)ccn2)cc(C2CCCN(C(=O)c3ccccc3)C2)n1 +OCC1OC(n2cc(I)c3c(Cl)ncnc32)C(O)C1O +O=C(O)CNc1ccc(-c2ccc(Cl)cc2)c(COc2ccc(-c3nc4cc(C(=O)O)ccc4n3C3CCCCC3)cc2)c1 +CCCCCCCCCCCCCCCC(=O)Nc1c(C)cc(C)c2c1OC(C)(C)C2 +CCOC(=O)c1c(C)nc(NCCNc2ccnc3cc(Cl)ccc23)nc1-c1ccccc1 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+CN(Cc1nc(N)nc(N)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1)c1ccccc1 +CCCC1(C)SC(NC23CC4CC(CC2C4)C3)=NC1=O +CC(C)(C)N(NC(=O)c1ccccc1F)C(=O)c1ccccc1Cl +O=C1CC2(CCCC2)CCN1OCCCN1CCN(c2nsc3ccccc23)CC1 +CNS(=O)(=O)c1ccc(NC=C2C(=O)Nc3ccccc32)cc1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2ccccc2-c2csnn2)n1 +CCN1CCCCC1c1nc(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)cs1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(F)c(Cl)c3)CC2)nc1 +Cc1ccc(C2c3c(C)c(N)c(C)c(C)c3OC2(C)C)cc1 +CCc1ccc(OP(=O)(NC(C)C(=O)OC)OCC2C=CC(n3cc(C)c(=O)[nH]c3=O)O2)cc1 +O=C1N(CCC2CCN(CC3COc4ccccc4O3)CC2)CCN1c1ccc(F)cc1 +Cc1ccc(COc2ccc(C=CC(=O)NC(CCCCCC(=O)NO)C(=O)Nc3cccc4cccnc34)cc2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(N3CCC(O)CC3)c2cn1)c1ccccc1 +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4ccc(OCc5ccccc5)cc4)o3)cc2Cl)CS1(=O)=O +Cc1cc(C=CC#N)cc(C)c1Nc1ccc(F)c(Nc2ccc(C=CC#N)cc2)n1 +COc1cc(-c2cnn(CCO)c2)ccc1Nc1ncc2ccnc(NC3CCCCC3)c2n1 +NCCCCC(NC(=O)CN(Cc1ccccc1)C(=O)CCc1ccccc1)B(O)O +CS(=O)(=O)N1CC2(CCN(C(=O)Nc3ccc(-c4ccccn4)cc3)CC2)c2ccccc21 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+O=C(CCN1CCC(c2cnccn2)CC1)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1 +COc1ccc2c(c1OC)CN(C)c1c-2ccc2cc3c(cc12)OCO3 +[H]c1c(Cl)ccc(COc2cccc(C(=O)O)c2OCc2ccc(Cl)c([H])c2Cl)c1Cl +O=C(NCc1cc(F)c(N2CCOCC2)c(F)c1)Nc1cccc2cnccc12 +COc1cccc(COc2ccc(OC)cc2CCCNC(C)=O)c1 +CC(C)(C)C(=O)Oc1cc(C(C)(C)C)ccc1CN=C(S)NCc1ccc(NS(C)(=O)=O)cc1 +CN(C#N)N(C)C(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C +CCS(=O)(=O)NCCN(C1CCN2CCc3ccccc3C2C1)S(=O)(=O)CC +CCCCC(=O)c1c[nH]c2ccc(CCc3ccccc3)cc2c1=O +CN1CCC(Nc2cc(-c3ccc(C(F)(F)F)cc3)c(C#N)c3nc4ccccc4n23)CC1 +CCCc1ccc(S(=O)(=O)NCC2CCCN2c2nc(NCc3csc(-c4ccccc4)n3)nc(NCC(C)C)n2)cc1 +CN1CCC(c2c(O)cc(O)c3c(=O)cc(-c4ccc(F)cc4)oc23)C(O)C1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1cc(C(F)(F)F)nn1-c1ccccc1F +CC(C)(NS(=O)(=O)c1cc(F)c(F)cc1F)C(=O)NC1C2CC3CC1CC(C(N)=O)(C3)C2 +CSc1nn2cc(-c3nc4cc(C(C)(C)C)ccc4o3)nc2s1 +COc1cc(OC)c(OC)cc1CNc1cnc2nc(N)nc(N)c2c1 +CSc1ccc(-c2nc(-c3ccncc3)c(-c3ccc(F)cc3)n2C)cc1 +O=C(Nc1ccccc1)N(Cc1cc(Br)ccc1O)c1ccc(Br)cc1 +O=C(CCCCCCNC(=O)N1Cc2ccccc2C1)NCC1CCOC1 +O=C(CC1CCCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1)NCc1ccncc1 +O=C(NC1COCCC1NC1CCC1)c1ccc(C(F)(F)F)cc1C1CC1 +CCOc1cc(COc2ccc3c(c2)NCCN(C(CCC(=O)OC)C(=O)NO)S3(=O)=O)cc(OCC)c1 +CC(C)CCOCc1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 +CCCC(=O)N1CCC(N2CCN(C(=O)c3c(NC(=O)NCC)sc4ccccc34)CC2)CC1 +CCCCc1ccc(Nc2nc3cc(Oc4ccnc(C(=O)NC)c4)ccc3s2)cc1 +CCCc1nc2cccnc2n1-c1ccc(Nc2nc3ccccc3s2)cc1 +CC(C)CCn1cc(-c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)nn1 +CCCCNc1ncc(-c2ccccn2)c(NC2CCNCC2)n1 +CCCOc1ccc(C#Cc2ccc(CC(C)NC(=O)C3CC3)cc2)cc1 +CC1(C)CN(c2ccc(C#Cc3ccc(F)nc3)cn2)C(=O)O1 +COC1CC(C)(C)c2ccccc2C1Nc1cc(OC2CC(O)C(COS(N)(=O)=O)C2)ncn1 +CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(C(=O)O)cc2)c([N+](=O)[O-])c1 +CC(Cc1c[nH]c2ccccc12)(NC(=O)CC1C2CC3CC(C2)CC1C3)C(=O)NC(CC(=O)O)Cc1ccccc1 +Cc1c(Cc2cccc(NS(N)(=O)=O)c2)c(=O)oc2cc(OC(=O)N(C)C)ccc12 +CC(=O)CCCCCC(NC(=O)C1CCCN(C)C1)c1ncc(-c2ccccc2)[nH]1 +OC(CNc1cc(-c2ccc(C(F)(F)F)c(Cl)c2)ncn1)c1ccccc1F +C=CC(=O)Nc1cc2c(Nc3ccc(Br)c(F)c3F)ncnc2cc1OCCNC(=O)CN(C)C 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+CCOCCOc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O +O=C(c1ccc(O)cc1)N1CCc2cc3c(cc2C1c1cccc(O)c1)OCO3 +Cc1ccc(OCCCc2cc(N)cc(CCCOc3ccc(C)cc3)n2)cc1 +CNc1nc(C)c2cc(-c3ccc(OC)nc3)c(=O)n(C3CCCC3)c2n1 +CC(NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C(=O)N1CC(C#N)C1 +O=S(=O)(Nc1ccncn1)c1ccc2c(-c3ccc(C(F)(F)F)cc3C3=CCNC3)cccc2c1 +O=C1NCCN1CCN1CCC(c2cn(-c3ccc(F)cc3)c3ccc(C(F)(F)F)cc23)CC1 +CC1(C)c2cc(S(=O)(=O)CCC(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +COC(=O)c1ccc(COc2ccc(-c3cnc4c(-c5nnn[nH]5)cnn4c3C3CCCCC3)cc2)cc1 +CCN1C(=O)c2cccc3c(NS(=O)(=O)c4ccc(C)cc4)ccc1c23 +NCc1ccc(Cl)cc1CNC(=O)C1CCCN1C(=O)C1NCc2ccccc21 +CNc1nc(Nc2ccc(-n3cncn3)cc2OC)ncc1C(F)(F)F +Cc1cc(C(F)(F)F)ccc1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCN(C(=O)C3CCC3)CC2)CC1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2ccc(CN3C(=O)CCC3=O)cc2)c1 +O=C(O)C1CN(C2CCC3(Cc4ccccc4Oc4ccccc43)C2)C1 +CC(NC(=O)C(CO)NS(=O)(=O)Cc1ccccc1)C(=O)NC1CCCN(C(=N)N)C1O +CC1=C(c2ncnn2C2CCC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 +CCC(O)(CC)C(=O)NC1CCc2c(Cl)c(OC)c(OC)c(OC)c2-c2ccc(OC)c(=O)cc21 +Cc1cc(NC2CC2c2ccccc2)n2nc(NC(C)c3cccc(Cl)c3)nc2n1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nnc(Nc2ccccc2)o1 +OCCCNc1ccc2c(c1)nc(-c1ccc3c(c1)OCO3)n1ncnc21 +CC(C)Oc1cc2c(-c3cc(N4CCNC(=O)C4)ncn3)n[nH]c2cc1F +CCCCCC(=O)c1ccc(OCCCN2CCN(S(=O)(=O)c3ccc(C#N)cc3)CC2)cc1 +CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCC(=O)N(CC)CC)cc1Oc1ncc(C(F)(F)F)cc1Cl +CCN(CCCS(C)(=O)=O)c1cc(C)nc2c1NC(=O)CN2c1ccc(C(C)C)cc1Br +CSc1ccc(CCCCCCC(=O)c2ncc(-c3ccccn3)o2)cc1 +COc1ccc(Nc2ccc(C(C)=O)cc2C(=O)O)cc1 +CN1C(=O)C(NC(=O)C2(C(=O)NCCC3CCCC3)CCC2)N=C(c2ccc(C(F)(F)F)cc2)c2ccccc21 +Cc1cc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4cccc(OC(F)F)c4)cc32)ccc1C(=O)NC1CC1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cc(COc3cccnc3)n[nH]2)cc1 +COCC1(c2ccc(F)cc2)ON=C2C(=Cc3ccc(-n4cnc(C)c4)c(OC)c3)CCCN21 +CCn1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CCC(O)CC3)n2)cn1 +CC1CN(c2nnc(Cc3ccccc3)c3c2CCC3)CCN1c1cnc(C(C)(C)O)cn1 +Cc1ccc(O)c(C(CCN2CC3CC3(C)C2)c2ccccc2)c1 +FC1(F)CCC(C=Cc2nc3cc(-c4ccccc4C(F)(F)F)ccc3[nH]2)CC1 +COc1cccc(S(=O)(=O)c2ccc(CNC(=NC#N)Nc3ccncc3)cc2)c1 +CC(C)CNc1nc(Nc2ccc(C(F)(F)F)cc2)c2nc(Nc3c(Cl)cccc3Cl)sc2n1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(N4CCOCC4)nc3)nc2n1 +O=C(CBr)Nc1cccc(Cn2c3c(c4ccccc42)CC2(O)C4Cc5ccc(O)c6c5C2(CCN4CC2CC2)C3O6)c1 +CC(NC(C)c1ccccc1Cl)C(=O)Nc1cccc(S(=O)(=O)N2CCCCC2)c1 +O=C(Nc1ccc(C(F)(F)F)cc1)NC1CCN(S(=O)(=O)C2CC2)CC1 +CN1CCN(OC(=O)NC2CC3(C)OC2(C)C2C(=O)N(c4ccc(C#N)c(C(F)(F)F)c4)C(=O)C23)CC1 +Cc1ccc2c(c1)CC(CCN(C)C)=C2C(C)c1cnccn1 +COC(=O)c1sc(Br)cc1S(=O)(=O)N1c2cc(Cl)ccc2NC(=O)C1C +O=C(NO)c1ccc(CNC(=O)c2cccc3ccccc23)cc1 +COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cnc(C)nc4)ccc23)cc1 +Cc1ccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-n1ccnc1 +OC1CCc2cccc(Nc3ncc(-c4ccccc4)o3)c2C1 +Cc1nn(-c2ccnc(Nc3ccc4[nH]cc(C(=O)C(F)(F)F)c4c3)n2)cc1CN1CC(O)CO1 +O=C(O)C1CCCN(CCC=C(c2ccccc2F)c2ccccc2Cl)C1 +CCn1cc(-c2cccc(C(C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)cn1 +O=C1C(=O)N(Cc2cccc3ccccc23)c2c(Br)cc(Br)cc21 +CN1C(=O)C(c2cccc(-c3cccnc3)c2)(c2ccc3c(c2)OCCO3)N=C1N +CC1(C)CCc2c(N3CCOCC3)nc3sc4c(NCCN5CCOCC5)ncnc4c3c21 +O=C(Cc1ccc(F)cc1)Nc1ccc2c(c1)CC(=O)N(O)C2=O +CCN(CC)S(=O)(=O)c1ccc(C(=O)NCc2nnc(SCC(=O)N3CCc4ccccc43)n2-c2ccccc2OC)cc1 +Oc1nc(-c2ccc(-c3c(COc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cn2)no1 +O=C(NCc1ccccn1)c1ccc2c(c1)Cc1c(-c3ccc(-c4ccc(O)cc4)cc3)n[nH]c1-2 +Cc1ccc(S(=O)(=O)Nc2cc(C3C([N+](=O)[O-])C(c4ccccc4Br)CCN3Cc3cccnc3)ccc2O)cc1 +CC(C)C(C(=O)O)N1CC(CN2CCC(c3ccc(F)cc3)CC2)C(c2ccccc2)C1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)c1C +CCCOC(=O)Nc1ccc(S(=O)(=O)N2CC(c3ccccc3)NC2=O)cc1CC +N#Cc1ccc(NC2CNC(C(=O)N3CCCC3C#N)C2)cc1C#N +O=C(c1cc2ccccc2o1)N1CC(=O)N(Cc2ccc(Cl)cc2)C(Cc2ccccc2)C1 +CC(=CC(O)CC(C)=CCCc1ccoc1)CCC(O)C1(C)CCC(=O)O1 +CC(C)Oc1cccc(-c2c[nH]c3ccc(-c4nnc(N)o4)nc23)c1 +COc1ccc(CC(N)c2nc3ccc(-c4cn[nH]c4)cc3c(=O)[nH]2)cc1 +COc1ccc(S(=O)(=O)C(C)(Cc2ccc(OCCN(C(C)C)C(C)C)cc2)C(=O)NO)cc1 +CCN(CCN1CCN(c2ccc(OCCOC)cc2)CC1)c1cc2nc(-c3ccco3)nn2c(N)n1 +CCN(CC)C(=O)Cn1c(-c2ccc(OC)cc2)nc2c(C)cc(C)cc21 +O=C(O)CCCCC=C(c1cccnc1)c1cccc(F)c1 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+O=C(O)c1n[nH]c2cc(Cl)c(-c3ccc4c(c3)CCO4)cc12 +CC(NC(=O)c1cccc(CN2C(=N)NC(C)(C(C)C)CC2=O)c1)c1ccccc1 +CNc1nc(-c2ccccc2Cl)c2c(n1)N(c1c(Cl)cccc1Cl)C(=O)NC2 +CCOc1ccc(Cc2ccccc2OC2CC(CO)C(O)C(O)C2O)cc1 +Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(C#N)c(Oc3ccccc3)c(C#N)c2c1 +COc1ccc(-c2ccccc2N2CCN(CCCCCC(=O)NCc3ccc(OCCN4CCOCC4)cc3)CC2)cc1 +Cc1c(CN2CCCC2)cc(-c2ccc(N)cc2)n1Nc1ccnc2cc(Cl)ccc12 +Cc1cccc(CNc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1C +CNC(=O)C1CC(O)C(n2cnc3c(NC)ncnc32)O1 +O=C(Nc1cccnc1)N1CCC(Cc2cccc(Oc3ccc(Cl)cn3)c2)CC1 +O=C1c2ccc(CN(CCO)CCO)cc2C(=O)c2nccnc21 +CC1(C)N=C(N)N=C(N)N1OCCCOc1cc(Cl)c(Cl)cc1Cl +O=C(CCCN1CCN(C(=O)c2ccccc2)CC1)NC1c2ccccc2CSc2ccccc21 +Cc1cc(CCCCCCC(Cc2cc(C)c(F)c(C)c2)C(=O)NO)ccc1F +Fc1ccc(-c2nc(CN3CCN(c4ccccc4)CC3)cn2-c2ccc(F)cc2)cc1 +O=C(NC1CC(O)CC1OC(=O)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1)c1ccc(O)cc1 +CC(C)CCNC(=O)C(C)NC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)C(C)(C)C)C(C)C +Cc1cc(C(=O)O)c2nc(-c3c(F)c(F)c(-c4ccc(NC(=O)C5CCCN5)cc4)c(F)c3F)[nH]c2c1 +Oc1ccc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)cn1 +Cc1ncoc1-c1nnc(SCCCN2CCC3CC3(c3ccc(C(F)(F)F)cc3)C2)n1C +C=C(c1ccc(F)cc1)n1cc(Cl)cc2c(-c3ccc(-n4cnc(C)c4)c(OC)c3)nnc1-2 +CNS(=O)(=O)c1ccc(NC2CCCCC2)c(NCc2ccncc2)c1 +Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cc(F)cc1-c1ncnc2[nH]c(C3=CCOCC3)cc12 +CC1C=CC(=O)C(O)C(O)CC=Cc2cc(CCCn3ccnc3)cc(O)c2C(=O)OC1C +Cc1ccc2oc(S(=O)(=O)c3ccc(O)nn3)c(C)c2c1 +CCc1nnc(NC(=O)C(C#N)=Cc2ccc(OCc3ccc(F)cc3C(F)(F)F)c(OC)c2)s1 +Cc1c(CN(CCc2ccc(F)cc2)C2CCN(C(=O)c3c(F)cccc3F)CC2)c(=O)n(-c2ccc(F)cc2)n1C +C=C1C(=CC=C2CCC(CCCCCCC(C)(C)O)C3(C)C2CCC3C(C)CCO)CC(O)CC1O +CCn1c(C(F)(F)F)nc2c1CN(C(=O)CC(N)Cc1cc(F)ccc1F)CC2 +CCc1nn(Cc2ccc(C)nc2)c2cccc(NC(=O)c3cnc4ccccn34)c12 +Cc1cc(CC(C)C)ccc1-c1ccccc1S(=O)(=O)Nc1onc(C)c1C +O=C(Nc1nc(-c2ccc(C(F)(F)F)cc2)cs1)c1ccc(Nc2ccncn2)cc1 +NCC=Cc1cncc(-c2cnc(Nc3cc(N4CCOCC4)ccn3)s2)c1 +COc1nccnc1C(C)C1=C(CCN(C)C)Cc2cc(C)ccc21 +CCCCCCCCCCCCCCN1CC(CO)NC(=O)C1C(C)C +CCCc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1-c1ccccc1 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+O=C(c1ccccc1)n1cc(C2=CCNCC2)c2cc(F)ccc21 +CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2Cc2cnccc2Cl)C1 +CC(C)c1ccc(S(=O)(=O)n2c(CCN3C(=O)c4ccccc4C3=O)nc3cc(Cl)c(Cl)cc32)cc1 +COc1ccc(C2SCC(=O)N2CCNc2ccnc3cc(Cl)ccc23)cc1O +Cc1ccc(-n2nc3c4cc(CCc5ccccn5)ccc4[nH]c(=O)n3c2=O)cc1 +O=C(N=C1SSC2=NCCN21)c1ccc(C(F)(F)F)cc1 +O=C1NCCN1c1ccc(S(=O)(=O)Nc2ccc3c(c2)CCC3)cc1 +Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCCc3ccccc3)C2=O)cn1 +CN(C)c1cccc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)n1 +CC1(O)c2ccc(C#Cc3cc(Cl)ccc3OCC(=O)O)cc2S(=O)(=O)C1(C)C +Oc1ncnc2nc(-c3ccc(F)cc3)c(-c3ccc(F)cc3)nc12 +CN1C2CCC1C(C(=O)OCCc1ccc(N=C=S)cc1)C(OC(=O)c1ccccc1)C2 +CC(C)C(OC(=O)N1CCN(C(=O)N2C(=O)C(Cc3cccc(CN)c3)C2C(=O)O)CC1)C(C)C +CCCCc1nc(Cl)c(C(=O)Oc2ccc3c(c2)CCC3)n1Cc1cccc2c1ccn2-c1ccccc1-c1nn[nH]n1 +Nc1ccc(I)cc1C(=O)NCC(=O)NC1CCN(Cc2ccc(Cl)cc2)C1 +COc1ccc(NC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NCC2(c3cccnc3)CCCCC2)cc1 +O=C(O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(C#Cc2ccc([N+](=O)[O-])cc2)s1 +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(-c3noc(C4CCC4)n3)cc12)C(=O)O +CN(C)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +C=CCN(CC=C)c1ccc2c(c1)CC(CCN(C)C)(c1ccc(Cl)cc1)OC2=O +COc1ccc(C(=O)c2cc(OC)c(OC)c([Se]C)c2)cc1Br +O=S(=O)(c1cc(Cl)c2oc3c(c2c1)CNCC3)c1ccccc1Cl +Cc1ccc2c(C)ccc(-n3c(C)nnc3SCC(=O)Nc3ccc(S(N)(=O)=O)cc3Cl)c2c1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCc2ccccc2)CCO1 +COCCOc1n[nH]c2cc(NC(=O)NCc3ccc(F)cc3)ncc12 +COCC(C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O +N#Cc1ccc(OC2CCC(NC(=O)Nc3ccc(OC(F)(F)F)cc3)CC2)cc1 +CC1SCc2ncnc(N3CCN(C(=O)C(Cc4ccc(Cl)cc4)CN4CCCC4)CC3)c21 +COc1cc(C=NNC(=O)C(OC)c2cccc(N3CCCC3)c2)cc(OC)c1Br +Cc1nc(NCCc2cccnc2)cc(-c2ccc3ncsc3c2)n1 +CCN(CC)CCCC(C)Nc1c2ccc(OC)cc2nc2ccc(Cl)cc12 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3cccc(Cl)c3)n[nH]c2C1(C)C +CN(C)c1ccc(-c2cn(CCCCCCC(=O)NO)nn2)cc1 +N#Cc1c(N=Cc2cccnc2)c(C(=O)Nc2ccccc2)n2c1CCC2 +NS(=O)(=O)c1ccc(-c2[nH]c3ccc(Br)cc3c2-c2ccccc2)cc1 +O=C(c1ccc(Cl)c(Cl)c1)N1CCC(CNCc2cccc(Cl)n2)CC1 +COCCOc1cnc2ccc(C(C)n3nnc4ccn(-c5cc(C)ns5)c(=O)c43)cc2c1 +Clc1ccc(N2CCN(CCc3nc4ccccc4o3)CC2)cc1 +COC(=O)C1C(c2ccc(-c3ccc(N=[N+]=[N-])c(I)c3)cc2)CC2CCC1N2C +O=C(Cc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(O)cnc32)CC1 +O=C(c1ccc(Cl)cc1)N(c1ccc(Br)cc1)C1CCN(Cc2ccccc2)CC1 +CN1C(C(=O)NC(C=O)Cc2ccccc2)Cc2ccccc2S1(=O)=O +Cc1nc(S(C)(=O)=O)ccc1Nc1ncnc(OC2CCN(C(=O)OC(C)C)CC2)c1OC(F)F +O=C(Cc1ccccc1O)NCCCNCCNCCCNC(=O)Cc1ccccc1O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CN4CCN(C)CC4)c(O)ccc3nc2-1 +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)c1cccc(CO[N+](=O)[O-])c1)CC2 +O=C(NC1CCCC1NC(=O)c1cc2ccc(Cl)cc2[nH]1)c1ccc(-n2ccccc2=O)cc1 +Cc1cc(-c2nnc3n2CCCCC3)c(C)n1-c1ccc(Cl)cc1 +COc1ccc(OC(CCN2CCN(c3noc4ccccc34)CC2)c2ccccc2)cc1 +CCc1[nH]c(N)nc2ncc(CCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)c1-2 +CCN(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)C(CC)(C(=O)OC)c1ccccc1 +Cc1cc(-c2cccc3cc[nH]c23)c(Cl)c2c1NC(C)(C)C(=O)C2C +COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OCCCCC(=O)O +Cc1ccc(O)cc1C(=O)NC(CSc1ccc2ccccc2c1)C(O)Cc1ccccc1C(=O)NC(C)(C)C +O=C(Nc1ccc(C(=O)N2CCC3(CCCNC3)C2)cc1)N1Cc2ccncc2C1 +Cc1c(C(=O)NCCCN2CCN(c3ccc(F)cc3)CC2)cc(-c2ccccc2)n1C +CC(C)Cc1ccc(C(C)C(=O)N2CCC(C(=O)Nc3ccccc3[N+](=O)[O-])CC2)cc1 +CCCCC(NC(=O)OC1C(=O)N(C(=O)CCCc2ccccc2)CC1(C)C)C(=O)C(=O)NC(C)c1ccccc1 +Cn1c(-c2cccc(F)c2)nc2c(N)nc(C#CC(C)(C)O)nc21 +CC1=CC(C)=[N+]2C1=C(c1ccc(OCCCN3CCCCC3)cc1)c1c(C)cc(C)n1[B-]2(F)F +Cc1ccc(-c2cc(C(=O)NC(C)CO)cc3c2cnn3-c2ccccc2C)nc1 +COc1ccc(-c2cc(-c3ccc(C(=O)NCCN4CCOCC4)cc3)cnc2N)cn1 +CC(C)(O)Cc1ccc2c(c1)c1cc(OCCC3CC3)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 +CNc1ccc(-c2nc(=O)n(CCC3CCCO3)c3c2oc2ncc(-c4cnn(C)c4)cc23)nc1 +O=C(NCc1ccccc1)Nc1[nH]nc(-c2ccccn2)c1C1CC1 +O=C(Nc1ccc2[nH]cc(C3CCN(CCc4ccccc4)CC3)c2n1)c1ccc(F)cc1 +Cc1cnc(-c2cc(N3CCN(C(=O)CO)CC3)ncc2Cl)c(C)c1 +Cn1ccc(CNC(=O)N2C(=O)N(c3cccc(C(F)(F)F)c3)C3=C(C(=O)CC3)C2c2ccc(C#N)cc2)n1 +CCC(CN1CC2CCC(C1)O2)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +O=S(=O)(Nc1ccc2c(c1)ncn2Cc1ccccc1)c1ccccc1F +CCC(C1CC1)n1nc(C)nc(Nc2cc(C)c(OC)cc2C)c1=O +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)OC)c3ccccc3)CC2)c(F)c1 +COc1ccc(F)c(-c2nc(C(=O)Nc3cnccc3C3CC(C)CC(N)C3)ccc2F)c1 +O=C(O)Cn1c2c(c3ccccc31)CN(C(=O)c1cccc(Cl)c1)CC2 +O=C(NCCc1nc(-c2ccccc2F)cs1)c1cccs1 +Cn1nc(C(C)(C)C)cc1C(=O)NC(Cc1cccc(-c2nnc(CO)o2)c1)C(=O)NCC#N +O=c1[nH]c(-c2cccc(C#Cc3ccccc3)c2)ncc1O +O=C(NCc1ncc(S(=O)(=O)c2ccccc2)cn1)c1ccc2nccn2c1 +C=CC(=O)N1CCCCC(n2c(NC(=O)c3cccc(C(F)(F)F)c3)nc3cccc(C)c32)C1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4nncs4)ccn23)c1 +COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(C1CCOCC1)C2=O +Nc1nc(OC2CCCC2)nc2c1ncn2C1OC(CO)C(F)C1O +CCCCC1CN(CC2CCCCC2)C(=O)OC12CCN(C1CCN(C(=O)c3c(C)cccc3C)CC1)CC2 +NC(=O)c1cc(-c2ccc(CN3CCOCC3)cc2)nc2c1[nH]c1cc(N)ccc12 +NCCCCNCc1ccc(OC2=CC(=O)c3cc4ccccc4cc3C2=O)cc1 +CC1OC(=O)C2CC3CCCCC3C(CCCN3CCc4ccccc4C3)C12 +COc1ccc(C2CN(C(C)c3nn4c(C5CCOCC5)ncc4c(=O)[nH]3)C2)c(F)c1 +Cc1ccc(NC(=O)CC(N)C(=O)O)cc1-c1cccc(C(F)(F)F)c1 +COc1nc(Nc2nc3n(n2)CCCC3c2ccc(F)cc2)ccc1-n1cnc(C)c1 +CC(=O)c1ccc(OCCCN2CCC(NS(=O)(=O)c3ccc(C#N)cc3)C2)cc1 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+CCN(CC)Cc1cc(N(c2cc(C)nc3cc(Cl)ccc23)S(=O)(=O)c2ccc3ccccc3c2)ccc1O +CC1C(=O)NCC1C(=O)Nc1cc(-c2cccc(COC(C)C(F)(F)F)c2)n(-c2ccccc2)n1 +COc1cc2c(N)nc(N3CCN(C(=O)CC(N)c4ccccc4)CC3)nc2c(Br)c1OC +CC(CS)C(=O)N1C(SCc2ccccc2)CCC1C(=O)O +NC(Cc1nc2cccc(Cl)c2cc1CP(=O)(O)O)C(=O)O +CN1CCN(Cc2ccc(Nc3ncc(Cl)c(Nc4ccccc4C(=O)N(C)C)n3)cc2)CC1 +CN(C)CC1CC2c3ccccc3Cc3ccc(-c4ccccc4)cc3N2O1 +CCCc1cc(Nc2ccnc3cc(Cl)ccc23)cc(CNC(C)(C)C)c1O +COC(=O)c1cc(-c2c[nH]c3ccccc23)[nH]n1 +C#CCN(Cc1cnc2nc(N)nc(N)c2c1C)c1cc(OC)c(OC)c(OC)c1 +Cc1nn(Cc2ccc(-c3nc4cc(Cl)ccc4[nH]3)cc2)c(C)c1CC(=O)O +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(CC3CCN(C)CC3)C2=O)cc1 +Cc1csc(-c2cc(-c3c(C)noc3C)c3n(c2=O)CCCc2ccncc2-3)n1 +CONc1nc(C#Cc2ccc(CC#N)cc2)nc2c1ncn2C1OC(CO)C(O)C1O +COCCOc1c(C=C2SC(=O)NC2=O)cccc1C(F)(F)F +COc1cc(F)ccc1-c1nc2c(NCCCNC(=O)C3CCC3)c(Br)cnc2[nH]1 +O=c1cc(C=Cc2ccc(O)c(O)c2)oc2cccc(O)c12 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc(-c5cccnc5)n[nH]4)c3)cc2C1 +Cc1ccc(N2CCN(C(=O)C3CCS(=O)(=O)CC3)C(c3cccc(F)c3)C2)nc1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cn2ccnc2)cc1 +CC1CCC2(C(=O)N3CCNCC3)CCC3(C)C(=CCC4C5(C)Cc6cn[nH]c6C(C)(C)C5CCC43C)C2C1C +C#Cc1c(Oc2ccc(-n3cc(C(=O)NCc4ccc(F)cc4)ccc3=O)cc2F)ccnc1N +NC(=O)Nc1sc2c(c1C(N)=O)CCc1nn(C3CCCN(Cc4ccc(Cl)cc4)C3)cc1-2 +Cc1ccc2nc(N(Cc3ccc(F)c(C(F)(F)F)c3)S(=O)(=O)c3ccccc3)c(C)n2c1 +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)Nc5ccc(Cl)c(Cl)c5)cn4c3)cc2)CC1 +CC(=O)N1CCC(c2nc(-c3ccc([S+](C)[O-])cc3)c(Sc3ccc(Cl)cn3)o2)CC1 +O=C(O)c1cc(-c2ccsc2)c2ccc(OCc3c(F)cc(F)cc3F)cc2c1 +CCOC(=O)c1cccc(NC2=NC(N)=NC3(CCCCC3)N2)c1 +Cc1ccc2c(-c3ccnc(Nc4ccc5c(c4)OCCO5)n3)c(-c3ccc(F)cc3)nn2n1 +CCc1c(C#N)c(-c2ccc(-c3cccc(F)c3)cc2)c(C(=O)O)n1C +O=C(OCCC12CC3CC(CC(C3)C1)C2)c1cc(N(O)C2CCCO2)on1 +COc1ccc(C=C2CNCC(=Cc3ccc(OC)c(O)c3)C2=O)cc1O +COCC(=O)NC(C)CNc1nc(-c2ccc(C(C)(C)O)nc2)cc2ncn(C)c(=O)c12 +CC1C(c2ccc(F)cc2)OC(=O)N1c1cc(F)cc(C#N)c1 +COCOc1cc(OC)c(OC)cc1-c1c(C(=O)OC)[nH]c(C(=O)OC)c1-c1ccc(OC)c(OC)c1 +CC(C)(C)c1cc(COCC(c2ccccc2)N2CCNCC2)cc(C(C)(C)C)c1 +CC(c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2)OC1=O +Cc1cc(F)ccc1Nc1nc(N(C)c2ccccc2)c2cccc(OCCO)c2n1 +COc1ccc2ccc(=O)oc2c1C1=NN(S(=O)(=O)c2ccc(Cl)cc2)C(c2ccc(SC)cc2)C1 +CCC#CCC(C)C(O)C#CC1C(O)CC(F)C1CC(=O)CCCCC(=O)O +COc1cc(Nc2nc3n(n2)CCC(=O)N3Cc2ccccc2C)ccc1-c1cnnc(C)c1 +O=c1[nH]c(CN2CCCCC2)nc2cc(-c3cn(Cc4ccccc4)c4ccccc34)sc12 +Cc1ccc(C(O)C2CCCC3=Cc4c(cnn4-c4ccc(F)cc4)CC32C)cc1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCOC1CCN(Cc3ccccc3)CC1)C2 +CCOC(=O)c1sc(-c2ccncc2)nc1-c1ccccc1Cl +Cc1ccc(-c2ccc(-c3cc(=O)cc(N4CCOCC4)s3)cc2)c2ccccc12 +N#CCNC(=O)C(Cc1ccccc1)NC(=O)c1ccc(CN=[N+]=[N-])cc1 +CN(C)Cc1cc(C(N)=O)ccc1Oc1ccc(OC(F)(F)F)cc1 +CN1CC(N2CCN(c3cc(C(F)F)cc(Nc4nc(NC5CC5)c5ncc(C#N)n5n4)c3Cl)CC2)C1 +CC(=O)NC(C)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 +CC(C)C(=CC(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)N)c1 +O=C(Oc1ccc(S(=O)(=O)c2ccc(OC(=O)C(Cl)=C(Cl)Cl)cc2)cc1)C(Cl)=C(Cl)Cl +OCC1OC(c2ccc(Cl)c(Cc3ccc(O)cc3)c2)C(O)C(O)C1O +OCC1OC(c2cccc(Cc3ccc4cccc-4cc3)c2)C(O)C(O)C1O +CCCCCCNC(=O)N1CCc2cc(S(=O)(=O)Nc3ccccc3)ccc21 +O=c1[nH]c2ccc(Nc3cccc(C(F)(F)F)c3)cc2s1 +CN1CCc2c[nH]c3c2C1=CC(=[NH+]C=Cc1ccc(O)cc1)C3=O +CCOCN(C)CNCC(=O)C(CC(=O)O)NC(=O)C(CC)n1ccnc(NCc2nonc2C)c1=O +Cc1ccc(CNC(=O)c2ccc(Cn3cc(-c4ccc(C)cc4)nc3-c3ccncc3)cc2)cc1 +CC(C)(N)C(=O)N1CCC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCCCC3)c2)CC1 +CCCC(CCC)C(=O)OCC1(CO)CC(=Cc2ccc(Cl)cc2)C(=O)O1 +Cn1cc(-c2cnc(N)c(-c3ccc(C(=O)NC4CC4c4ccccc4)c(F)c3)c2)cn1 +Cc1n[nH]c2nccc(-c3ccc(NC(=O)NC4CCC4)cc3)c12 +N=C(N)c1cccc(Oc2ccc(N)c(Oc3cccc(C(=N)N)c3)n2)c1 +Cc1c(Cl)cccc1N1CCN(CCCNC(=O)c2nc(-c3ccccc3)n(-c3ccccc3)c2Cn2cncn2)CC1 +CC(C)CNC(=O)c1cnc(NCCCn2ccnc2)nc1NCC1CCCCC1 +NC1=NC(CCc2ccc(Nc3cccc4cccc(Cl)c34)cc2)CO1 +O=c1[nH]c(CNc2ccccc2)nc2c1sc1ccc(Cl)cc12 +CCCN1C(=O)C(NC(=O)Nc2ccc(N3CCC(c4ccncc4)CC3)cc2)N=C(CCc2ccccc2)c2ccccc21 +CC(C)(C)NS(=O)(=O)c1ccc(NC2C3CC4CC(C3)CC2C4)c(NCc2ccccc2)c1 +COc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(CCCOc3ccccc3)CC2)cc1 +COCCCOc1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)cc2occc12 +CON=Cc1c(N)ncnc1N1CCN(C(=O)Nc2ccc(C3CCCCC3)cc2)CC1 +NC(C(=O)Nc1cc(C2CC2)[nH]n1)c1ccccc1 +O=C(O)C(=O)c1cccc(OCc2ccccc2Cl)c1OCc1ccccc1Cl +COc1ccc(S(=O)(=O)N2CCC(CCCC(=O)NO)CC2)cc1OC +CCCS(=O)(=O)Nc1cc(F)cc(-c2[nH]c(C3CC3)nc2-c2ccncn2)c1Cl +Cc1ccc(-c2nnc(-c3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)o2)cc1Nc1nccc(-c2cccnc2)n1 +Cc1cc(C(N)=O)ccc1-n1nc(C(F)(F)F)c2c(-n3cnc(-c4cccnc4)c3)cccc21 +N#CCNC(=O)C(Cc1cccc(-c2nnco2)c1)NC(=O)c1ccccc1 +O=C(C=Cc1cccn1Cc1ccccc1)CC(=O)C(=O)O +CC(C)n1c(Nc2ccc(C(=O)Nc3cccc(F)c3)cc2)nc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21 +CC(C1=C(CCN(C)CC#N)Cc2ccccc21)c1cnccn1 +CNc1cccc(NC(=O)CN2C(=O)N(CC(=O)C(C)(C)C)c3ccccc3N(C3CCCCC3)C2=O)c1 +CCC(=O)NCCOCCOCCOCCNS(=O)(=O)c1cccc(C2CN(C)Cc3c(Cl)cc(Cl)cc32)c1 +O=C(Nc1cccc(Nc2cc3c(cc2Cl)C(=O)NC3=O)c1)c1cccc(Cl)c1 +CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3Cc2ccoc2)c2cccc(C(C)=O)c2)cc1 +Nc1ccc(S(=O)(=O)c2ccc(-c3ncc(C(O)(C(F)(F)F)C(F)(F)F)cc3C#CCO)cc2)cn1 +N#Cc1ccc2c(c1)C(c1ccc3c(n1)CCCC3O)C(=O)N2 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+NS(=O)(=O)c1nnc(NC(=O)CCN2C(=O)c3cccnc3C2=O)s1 +CCOc1cc(CNCCCN2CCOCC2)cc(Br)c1OCc1ccccc1Cl +CCC(NC(=O)c1cc(C(=O)NC(CC)c2ncccc2OC)n2c1COCC2)c1ccccc1 +O=C(C1CCN(c2cc(Oc3ccc(F)cc3F)ncn2)CC1)N1Cc2ccccc2C1 +CC(C)(C)NC(=O)NCCc1nc2cc(S(=O)(=O)NCc3ccc(C(F)(F)F)c(F)c3)ccc2n1Cc1ccccc1 +CC1(C)OC2CCC(C)(O)C(CCC3C(C=O)=CCC4C(CCC4(C)O)C3(C)C)C2(C)CCC1=O +CC(=O)NNC(=O)CSc1nnc(Cc2csc(NCCC(=O)O)n2)n1NC(=O)c1ccccc1 +O=C(Nc1ccc(O)cc1)c1ccc(N2CCN(C(=O)OCc3ccccc3)CC2)cc1 +Cc1nnc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)sc2C(F)(F)CO3)o1 +COc1ccc(CNC(=O)c2ccc(OC(F)F)cc2)c(C(F)(F)F)c1 +NC(=O)c1cccc2c(NCc3ccc(NC(=O)c4cc(C(F)(F)F)n[nH]4)cc3)ncnc12 +CCc1c(-c2ccc(N3CCc4cccc(C(=O)Nc5nc6ccccc6s5)c4C3)nc2C(=O)O)cnn1CC1CCCCC1 +CN1CCCN(Cc2cccc(-c3cccc(CNC(=O)c4ccc5c(c4)OCO5)c3)c2)CC1 +COC(=O)c1cc([N+](=O)[O-])c(NC(C)=O)cc1OC(C)C +O=C(Nc1ccc(F)c(C(F)(F)F)c1)C1CCN(C(=O)Cn2c(=O)sc3ccc(Cl)cc32)CC1 +O=C(CCCCCN1C(=O)c2ccc(NC(=O)c3ccc([N+](=O)[O-])cc3)cc2S1(=O)=O)NO +O=C(Nc1cn(CC(O)CN2CCCCC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 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+CC(=O)Nc1ccc2[nH]cc(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 +O=C(CCCCN1CCC(c2ccccc2)CC1)n1c2ccccc2c2ccccc21 +Cc1cccc(OCC(=O)NCC(=O)NN=Cc2cc(Br)cc(Br)c2O)c1 +COC(=O)c1c(-c2c(F)cccc2Cl)noc1C=CNc1ccc(OC)cc1 +CCCN1CCc2cccc3c2C1Cc1cccc(OCCCn2cc(CN4CCN(c5ccccc5OC)CC4)nn2)c1-3 +CC(=Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NC(CO)C(=O)O +COc1ccccc1N1CCN(CCC2Cc3ccccc3C2=O)CC1 +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1nc(Cl)cs1)COCC3 +CN1CCN(CCCNCc2cn(-c3ccc(C(F)(F)F)cc3)nc2-c2ccc(Cl)cc2)CC1 +NC(=O)n1cc(NC(=O)N2C(C(=O)NCCOC(F)(F)F)CC3CC32)c2ccccc21 +COc1cc(Nc2ncc(C(=O)NO)cn2)cc(C(F)(F)F)c1 +COC(=O)c1cc(C(O)CN2CCC(n3c(O)nc4ccccc43)CC2)ccc1O +Oc1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)c1c-2ccc2cc(O)ccc12 +CC(C)(C)c1nc(N2CCN(CCCCNC(=O)c3cn4cccnc4n3)CC2)cc(C(F)(F)F)n1 +CCC(CC)(NC(=O)c1cc(OCC2(C)COC2)c(C2CC2)cn1)C(=O)NCCCF +O=C1NN=C(c2cnns2)C1=Cc1cc2c([nH]1)CCCC2 +CCNC(=O)Nc1cc(Nc2ccccc2)c(C(=O)Nc2cccc(Cl)c2)cn1 +COc1ccc(CNCc2cc(-c3ccnc4cc(Cl)ccc34)ccc2O)c(OC)c1 +COC(=O)N1CCC(Nc2ncccc2-c2cnc3[nH]ccc3n2)CC1 +CC(=NOC(=O)Nc1ccc(F)cc1)c1cccc(-c2ccccc2)c1 +COc1ccc(S(=O)(=O)N(Cc2ccccc2)c2ccccc2C(=O)NO)cc1 +COc1cc(-c2cccc(Cl)c2C)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C)Oc1ccc(-c2nc(-c3cccc4c(C(=O)O)c[nH]c34)no2)cc1Cl +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)OCCN3C)cc1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(Cl)cc2)c2c(n1CC(=O)O)CCNC2=O +COc1ccc(-c2noc(C)c2C(=O)N=C(N)NCc2cc(Cl)cc(Cl)c2)cc1 +N#Cc1cc(C(=O)c2ccc(Cl)cc2)n2c1ccc1ccccc12 +CCOc1cc2c(cc1C(=O)c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C +Cc1nc(NC(=O)c2ccc(C(=N)N)cc2)sc1CCC(=O)O +CCOc1ccc2cc(-c3nn(C(C)C(C)C)c(N)c3C(N)=O)cnc2c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3cccc(N(C)CC4CCCO4)n3)C2)cc1 +CCC(NC(=O)c1c(OCCCN(C)C)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +Clc1cc(C2CNCCO2)ccc1Nc1ncc(C2CC2)cn1 +Cc1cc(C)n(CC(C)NC(=O)c2ccc(NC(=O)N3Cc4ccc(F)cc4C3)cc2)n1 +CN(CC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +O=C(Nc1ccc(CC2=NCCCN2)cc1)c1ccc(C(=O)Nc2ccc(CC3=NCCCN3)cc2)cc1 +N#Cc1cnc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)nc1N +COc1cc(C)c(C(=O)NS(C)(=O)=O)cc1-c1ccc(C#CCO)s1 +Fc1ccc(NN=Cc2ccc(N3CCOCC3)cc2)c(F)c1 +COc1ccc(NC(=O)c2cc3c(cc2OC)C2(C)CCC(O)C(C)(C)C2CC3)cc1 +CCOc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1nc(Nc2ccc(N3CCN(C(C)=O)CC3)cc2OC)ncc1F +COC(=O)Nc1nc2cc(Oc3ccc(NC(=O)Nc4cccc(C(=O)O)c4)cc3)ccc2[nH]1 +O=S(=O)(c1cccnc1)N(CCCC(F)(F)F)c1sc2ccccc2c1Br +COC1CN(c2nc(-c3cccc(C)c3OCc3cc(C)c4c(c3)CCN(C3CCOCC3)C4)cs2)CCC1C(=O)O +NS(=O)(=O)c1ccc(C(=O)NCC(=O)NCC(=O)NCC(=O)NC(Cc2ccc(F)cc2)C(=O)O)cc1 +COc1cc(OC)c(NC(=O)C2c3ccccc3C(=O)N(C)C2c2cccs2)cc1Cl +O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1ccccc1 +CS(=O)(=O)NC1CCN(c2cc(-c3ccc(Cl)cn3)c(Cl)cn2)CC1 +C1=CC2(CCN(Cc3ccc4[nH]c5ccccc5c4c3)CC2)c2ccccc21 +CCCc1nc(SC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NC2CCCCC2)cc1 +O=C(NC1CN2CCC1CC2)c1cc2cccc(Cl)c2s1 +O=C(O)CCC1CCc2cc(-c3cc(OC4CCC4)cnc3F)ccc2O1 +NC(Cc1cc(F)ccc1F)C1CCC(N2CCCC(O)C2)CC1 +COCC(Cc1c[nH]c2ccccc12)(NC(=O)OCc1cc2ccccc2o1)C(=O)NC(C)c1ccccc1 +COc1cc(OC)cc(N(CCCN)c2ccc3ncc(-c4cnn(CCS(C)(=O)=O)c4)nc3c2)c1 +CNc1ccc2c(c1)N(C(=O)c1cc3cc(OC)c(OC)c(OC)c3[nH]1)CC2CCl +CN1C2CCC1CC(OC(c1ccccc1)c1ccccc1F)C2 +CCCN(CCCNC(=O)N(CC)CC)C1CCc2c(O)cccc2C1 +COCCOc1ccc(S(=O)(=O)N2CC(NOC)CC2C(=O)NO)cc1 +CCc1ncnc(N2CCC(O)C(C)C2)c1C#Cc1ccc(N)nc1 +Cc1ccc(NC(=O)c2nccnc2C(=O)Nc2ccc(F)cc2)c(-c2cccnc2)c1 +O=C(CCc1ccccc1)NNC(=S)NC(=O)c1ccc(Cl)cc1 +CCn1ncc2c(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)Nc4ccc(CO)cc4)cc3)nc21 +CC(=O)N1CCC(NC(=O)NC23CC4CC(F)(CC(F)(C4)C2)C3)CC1 +COc1ccc2c(c1)CN(C(=O)C(N)Cc1c(C)cc(O)cc1C)C(C(=O)O)C2 +CC12CCC(=O)C(Sc3ccccc3)=C1CCC1C2CCC2(C)C(O)C(C#N)CC12 +N#Cc1cc(-c2ccnc(Nc3cnn(CCO)c3)c2)ccc1OC1CCOCC1 +COc1cc2nc(N3CCN(C(=O)C4COc5cccc(C)c5O4)CC3)nc(N)c2cc1OC +O=C(c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1NC1CCC(CN2CCC(O)C2)CC1)C1CC1 +CCOC1(OCC)C2c3c(O)cccc3C([n+]3ccccc32)C1(C)C +CCCc1nc(C)n2nc(NC)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4cccc(=O)n4C)CC3)CN(C)C1C2 +Fc1ccc(SCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1 +CC(C)(C)OC(=O)NCC(=O)NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1 +CCCC(CCC)(c1ccc(O)c(CC)c1)c1ccc(O)c(CC)c1 +O=C(Nc1[nH]nc(C(=O)NC2CCCCNC2=O)c1Br)c1ccccc1Cl +CN1CCN(CCCN2CC3C(c4ccccc4)CC(N(C)C)(CC3c3ccccc3)C2)CC1 +COc1cnc(C(=O)Nc2cc(F)c(F)c(C3(C)CC(C(F)(F)F)OC(N)=N3)c2)c(C)c1 +CN(Cc1ccccc1)Cc1ccc(-c2cc3cc([N+](=O)[O-])ccc3oc2=O)cc1 +O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2ccc(Br)cn2)C2C=CC1C21CC1 +CCOC(=O)c1ccc(NC(=O)Cn2nnc(-c3ccc(C)cc3)n2)cc1 +O=C(Nc1ncc(F)s1)C(CC1CCOCC1)n1ncc2c(S(=O)(=O)C3CC3)cc(F)cc21 +CC(=O)Oc1ccccc1C(=O)OCOC(=O)CCCCC(CO[N+](=O)[O-])O[N+](=O)[O-] +O=C(NCC(c1ccc(C(F)(F)F)nc1)N1CCOCC1)c1c(F)cccc1Cl +O=C(NCC(C(=O)NO)N1CCN(Cc2ccccc2)CC1)c1ccc(OCc2c(C(F)(F)F)nn3ccccc23)cc1 +COc1ccc(NC(=O)c2ccc(Cl)c(Nc3ncnc4cnc(N5CCCN(C)CC5)nc34)c2)cc1C(F)(F)F +O=C(Oc1cn(-c2ccccc2)c(CSc2nc3ccccc3s2)cc1=O)c1ccccc1 +Cc1nnc(-c2c(-c3nnc(C4(C(F)(F)F)CC4)o3)nn(-c3ccc(Cl)cc3Cl)c2-c2ccc(Br)cc2)o1 +OC1CCCCCCCNc2ncc3c(C4CCOCC4)cn(c3n2)CCCC1 +CCOc1ccc2c(c1)c(C#N)cn2-c1ccc(C(=O)O)c(O)c1 +COc1cncc(-c2cc3c(-c4cccc(N5CCNCC5)n4)n[nH]c3cn2)c1 +CCCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)C2)cc1 +CC(C)N1CCN(C(=O)c2ccc3c(CN4CCCCC4)cn(S(C)(=O)=O)c3c2)CC1 +Cc1nc(-c2ccc(S(=O)(=O)Nc3cccc(-c4nnn[nH]4)c3)s2)cs1 +N=C(N)NCCCC(NC(=O)c1ccc(-c2ccccc2)cc1)B(O)O +O=C(C=Cc1cccc(S(=O)(=O)c2ccc3cccc(F)c3n2)c1)NO +CS(=O)(=O)c1ccc(Nc2ncnc(N3CCC(c4nc(C5CC5)no4)CC3)c2[N+](=O)[O-])cc1 +O=C(O)CCCOc1cccc(C=Cc2ccc3cc(Cl)ccc3n2)c1 +COCCOc1ncccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccco2)cc1 +CN1CCN(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c3ncccc23)CC1 +CCOC(=O)Oc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(C)=O)CC2 +Nc1nc(N)c2c(-c3cccc(Cl)c3)c(-c3ccc(F)cc3)[nH]c2n1 +O=C(NCCc1ccccc1Cl)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +OC1C(F)C2N=C(N3CCC3)SC2OC1C(O)C(F)(F)F +CS(=O)(=O)c1ccc(-c2sc3nc(C(F)(F)F)nn3c2-c2cccc(F)c2)cc1 +Cc1ccc2cccc(C)c2c1-n1c(C)nnc1SCC(=O)Nc1ccccc1Br +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2ccc(Cl)cc2)c(C)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=NOCc1ncc[nH]1 +COc1ccccc1N1CCN(CCN2C(=O)CC(c3ccc(Cl)cc3)CC2=O)CC1 +CCCN(C(=O)CCc1ccccc1)C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1 +CC(C)(O)C(=O)Nc1cccc(-c2ccc3nc(-c4cccnc4N)n(-c4ccc(C5(N)CCC5)cc4)c3n2)c1 +O=c1cc(OCc2ccc(F)cn2)ccn1-c1ccn2c3c(nc2c1)CCNC3 +CCCc1c(-c2ccc(O)cc2)cn(-c2ccc(O)cc2)c1-c1ccc(O)cc1 +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2nc3ccccc3s2)c1 +O=C1OCc2c1cc1ccc3c(c1c2-c1ccc2c(c1)OC(F)(F)O2)OCO3 +O=C(CCNC(=O)c1ccc(OC(F)(F)F)cc1)NC1CCCc2ccccc21 +O=C(Nc1nc2ccccc2c2cn(-c3ccccc3)nc12)c1ccco1 +O=C(NCc1ccc(S(=O)(=O)N2CC3(CCOCC3)C2)cc1)c1cnc2[nH]ncc2c1 +CN(C)CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccnc(N(C)C)c2)c1 +NC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1ccccc1 +COc1cc2c3c(c4ccc(O)cc4c2cc1OC)C(O)C1CCCN1C3 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n3n2CC2(C3)OCCO2)n1)c1ccccc1 +CN1CCN(c2cccc(Nc3nc4c(-c5ccc(P(C)(C)=O)cc5)cccn4n3)c2)C(=O)C1 +CC1CCN(CCCCCC(=O)n2c3ccccc3c3ccccc32)CC1 +CC(C)CC(CO)NC(=O)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +COc1ccc(C(=N)N2CCC(Oc3ccc(C(Oc4ccc5c(c4)CN(C(=N)N)CC5)C(=O)O)cc3)CC2)cc1 +CC(C)c1[nH]nc(OC2OC(CO)C(O)C(O)C2O)c1Cc1ccccc1 +O=c1oc2c3c(ccc2c(O)c1Cc1cccc2ccccc12)CCCC3 +COc1ccc(C(=O)NCCO)cc1C=Cc1ccc(Cl)cc1 +CC1OC23CC(c4ccc(C(F)(F)F)cc4)OC(=O)C2=CC1(C)OO3 +O=Cc1cc(-c2ccc(C(=O)O)cc2)cc(F)c1O +Cc1cnc2c(-c3ccc(F)cc3)c(-c3ccc(S(C)(=O)=O)cc3)nn2c1C +CCCOc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cc1Cl +COc1ccc2ccn(C3CCN(c4ccc(-c5cnn(C)c5)nn4)CC3)c2c1 +O=C1c2ccc(-c3ccc(F)cc3)cc2CCN1CCN1CCCCC1 +Nc1nn2cccnc2c1C(=O)Nc1cn(CC(=O)N2CC3CN(CC4CC4)CC3C2)nc1-c1cc(Cl)ccc1OC(F)F +CCn1cc(C(O)C2CCCN(c3nnnc4cc(N5CCOCC5)ccc34)C2)cn1 +O=CC(CC1CCCNC1=O)NC(=O)C(Cc1ccccc1)NC(=O)CCc1ccccc1 +COc1ccccc1N1CCN(CCCOc2c(C)cccc2C)CC1 +O=C(Nc1ccc(Cl)cc1)Nc1cccnc1Oc1cccc(C(F)(F)F)c1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1ccccc1F +CC(C)NCc1ccc(-c2ccccc2-c2ccc3c4n[nH]cc4c(=O)n(CC(F)(F)F)c3c2)o1 +O=c1n(Cc2nc3cc(Cl)ccn3c2CCCCO)c2cnccc2n1C1CC1 +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccsc1 +CC#CCn1c(N2CCCC(N)C2)nc2ccn(Cc3ccc4ccc(Cl)cc4n3)c2c1=O +CCOC1CCN(c2ncnc(CC)c2C#Cc2ccc(C)nc2)CC1 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+CCCNc1ncc(-c2ccc(Oc3ncc(NC(=O)Nc4cc(C(F)(F)F)ccc4S(=O)(=O)N(C)C)cn3)cc2)s1 +CCN(CC)CCN(CCNCCc1ccc(O)c2[nH]c(=O)sc12)C(=O)CCOCCc1cccc(F)c1 +CCCc1nc(COC)n2nc(O)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCCc1nc2[nH]ncc2c2nc(-c3ccc(C)cc3)nn12 +Cn1cc(C2=C(c3c4n(c5ccccc35)CCC(N)C4)C(=O)NC2=O)c2ccccc21 +CCCN1CCc2cccc3c2C1Cc1ccc2c(C)c(C)oc2c1-3 +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(-c3nccs3)cc12)C(=O)O +CN(C(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C)C1COC1 +CN(C(=O)CC(N)C1CCN(C(=N)N)CC1)C1CNC(NC(N)=O)=NC1=O +Cn1cnc(-c2ccnc(Nc3cc(Cl)c4[nH]c(C(=O)N5CCN(c6nccn6C)CC5)cc4c3)n2)c1 +Clc1ccc(C(OC2CC3CCC(C2)N3)c2ccccc2)cc1 +NC(=O)c1c(Oc2ccc(F)c(NS(N)(=O)=O)c2F)cc(F)c(F)c1Nc1ccc(I)cc1F +O=C(Nc1cc(C(=O)N2CC3CC2CN3)nn1-c1ccccc1)c1cc(-c2ncccc2F)ccc1Cl +CC(C)N1CCC(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CC1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4cccc([N+](=O)[O-])c4)cc3F)ccnc2cc1OCCCN1CCCCC1 +OCC(O)CN1C(CCc2cccc(F)c2)CCCC1CCc1cccc(F)c1 +CCNC(=O)OCc1c(COC(=O)NCC)c2n(c1CC)Cc1c(c3ccccc3n1C)C2 +COCCn1ccn2cc(C(=O)NCc3ccc(F)cc3)c(=O)c(O)c2c1=O +COc1cc(C#Cc2cn(C3CN(C(=O)C=CCN(C)C)C3)c3ncnc(N)c23)cc(OC)c1 +O=C(NC1CC1)c1ccc(Cl)c(Nc2nncc3c2cnn3-c2cc(F)ccc2F)c1 +CN1CCN=C1c1ccc(C(=O)N2CCN(S(=O)(=O)c3cc4cc(Cl)ccc4[nH]3)CC2CC(=O)O)cc1 +COc1cc2ncc(C#N)c(Nc3ccc(Br)cc3Cl)c2cc1OC +COc1cc2c(Cc3cnc4ccccc4c3)cnc(CC(C)C)c2cc1OC +CN(C)C1CCC(Nc2ncnc3ccc(C4CC4)cc23)CC1 +O=C(c1ccc(Cl)cc1)N1CCCC(c2nc(-c3ccccc3)no2)C1 +CC1(O)C2OC3(O)OC1C1C(O)NC(=N)NC1(C2O)C3O +Cc1ccc2c(c1)c(S(=O)(=O)c1c(Cl)cccc1Cl)c(C)n2CC(=O)O +CNC(C)C(=O)NC(C(=O)NC1CCCN(CCc2ccccn2)C1)C(C)(C)C +NC1CCN(Cc2ccn3ncnc(Oc4ccc(NC(=O)NC(=O)Cc5ccc(F)cc5)cc4F)c23)CC1O +CCN(CC)CCn1c(=N)n(CC(O)c2ccc(Cl)c(Cl)c2)c2ccccc21 +CC(C)N(C)CC=Cc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +COc1cc(OC)cc(N(c2ccc3ncc(-c4cnn(C)c4)nc3c2)C(C)CN)c1 +CCCCOn1c(Sc2cc(C)cc(C)c2)c(C(C)C)c(=O)[nH]c1=O +COc1ncc(-n2ncc3c(NCC(C)NS(=O)(=O)c4c(C)nn(C5CCCC5)c4C)cccc32)cn1 +CC(C)(C)c1cncc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC3)n2)n1 +CC(Nc1cc(-c2[nH]c([S+](C)[O-])nc2-c2ccc(F)cc2)ccn1)c1ccccc1 +CN1CCN(C(=O)n2oc(=O)c(-c3ccc(F)cc3)c2-c2ccncc2)CC1 +CC1(C)CN(C2=CCCC2=O)c2cc(C(F)(F)F)ccc2S1 +Cc1c(Cc2ccc(F)c(C(=O)N3CCN(C(=O)C4CCNC4)CC3)c2)n[nH]c(=O)c1C +CCCCN1CC(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(OCc3ccccc3)CN2)CC1=O +CN(C)C(=O)Cn1c(=O)c(C(=O)NCc2ccc(F)cc2)c(O)c2ncc(Cc3ccc(F)cc3)cc21 +N#Cc1ccccc1N1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +c1cc(-c2n[nH]c3cnc(-c4cncs4)cc23)nc(N2CCNCC2)c1 +Cc1cc(NC(=O)C(=O)c2cn(Cc3cc(C(C)C)no3)c3ccccc23)sn1 +CC(F)CS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(c2ccccn2)CC1 +CN1CC(=O)N(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1=O +CN(C)c1ccc(C(=O)NCCCCCCCC(=O)NO)cc1 +Cn1cncc1C(O)(c1ccc2nc(Cl)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1)c1cncn1C +C=C1C(O)CC(=CC=C2CCCC3(C)C2CCC3C(C)Cn2ccnc2)CC1O +CC(CNCc1ccccc1)C(=O)NC(CCc1ccc2c(c1)OCCCO2)C(C)C +CCCn1c(=O)c2nc(-c3cnn(Cc4cc(-c5cccc(OC)c5)on4)c3)[nH]c2n(CCC)c1=O +CC1=NC(C)=C(C(=O)O)C(c2ccccc2[N+](=O)[O-])C1=C(O)OCC=Cc1ccccc1 +CC(=O)NC(C)Cc1ccc(C#Cc2cnc3ccccc3c2)cc1 +O=C(CSc1nc2ccc(Nc3nc(N4CCCC4)nc(N4CCCC4)n3)cc2s1)NCc1ccco1 +Cc1ccc2nc(NC(=O)Nc3ccccc3N3CC4(CCN(CC(C)(C)C)CC4)c4c(Cl)ccc(O)c43)sc2c1 +CCCN(c1nccc(-c2c(OC)cc(OC)cc2OC)n1)C1(c2cccs2)CC1 +NCCCc1cc2cc[nH]c(=O)c2c2cc(-c3cn[nH]c3)ccc12 +N#Cc1ccc2c(c1)CCN(S(=O)(=O)c1cccc(C(=O)O)c1)C2 +CCCC(CCC)n1cnc2c1C(=O)N(C)CN2c1ccc(Cl)cc1Cl +COc1ccc(N2C(=O)OC(=Cc3ccc(O)c(Br)c3)C2=O)cc1 +Cn1c(CN2CCC(c3ccc(OC(F)(F)F)cc3F)CC2)nc2ncccc21 +COc1ccc(S(=O)(=O)N(Cc2ccc(C(C)C)cc2)C(C)C(=O)O)cc1 +CC1(C(=O)Nc2cnccn2)CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(C)O)oc12 +N#CCNCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(NC1CCC(CNc2cccnc2)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1cc(=O)oc2c1ccc1oc(C(=O)c3ccccn3)c(-c3ccccc3)c12 +Cc1sc(-c2noc(N)c2S(N)(=O)=O)cc1S(N)(=O)=O +CCCCCc1cc(O)c(CC=C(C)CCC=C(C)CCC=C(C)C)c(O)c1 +CS(=O)(=O)c1cc(Cl)ccc1CNC(=O)c1ccc(OCCC(F)(F)F)nc1 +CCCC(c1ccc(C(=O)NCCC(=O)O)cc1)C(c1ccc(Cl)cc1)c1c(C)sc2ccccc12 +Cn1nccc1-c1cc(NC(=O)c2ccc(F)c(F)c2)ccc1OCCN1CCOCC1 +COC(=O)C1CC(OS(=O)(=O)c2ccccc2)CN1S(=O)(=O)c1ccc(C)cc1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(C3CC3COC)nc(-c3ccccc3)n2)CC1 +O=C(NO)C1C(c2ccccc2)C1c1cncc(C(F)(F)F)c1 +Cc1cccc(-c2[nH]c(CNc3ccccc3F)nc2-c2ccc3ncnn3c2)n1 +CC1(c2ccc(OCCN3CCCCC3)cc2)c2ccc(O)cc2CCN1c1cccc(Cl)c1 +O=C(Nc1ccc(OC2CCN(C(=O)C3CCCC3)CC2)nc1)N1Cc2ccccc2C1 +O=C(NCc1cccc(-c2cccc(-c3cc4c[nH]ccc-4n3)c2O)c1)Nc1c(F)cccc1F +O=C1Nc2ncc(Br)cc2C1=Cc1cccc(Oc2ccccc2)c1 +CCC(C)(Cc1ccc(OCCCOc2ccc(C3CCCCC3)cc2Cl)cc1)C(=O)O +COc1ccn2c(c1)nc1c2c(=O)n(CC2CC2)c(=O)n1Cc1ccc(Cl)cc1 +O=C(Nc1ccc(-c2ccnc3[nH]cnc23)cc1)Nc1cccc(C(=O)NC2CCCC2)c1 +CCCC[S+]([O-])c1sc2nc(-c3cccs3)ccc2c1N +CC(C)(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccon3)cc1)C2=O +CCCCCC(O)C=CC1CC(F)(F)C(=O)N1CCc1ccc(C(=O)O)cc1 +CCCCCN1CCC(COc2nc3ccsc3n3cccc23)CC1 +CCCCCc1ccc(CN(C(Nc2ccc(OC)cc2OC)=C2C(=O)OC(C)(C)OC2=O)C(C)CCCCC)cc1 +Cc1cccc(C)c1COc1ccc2c(-c3ccccc3)cc(C(=O)O)cc2c1 +CC(Cc1n[nH]c(=O)c2c1CCCC2)c1cccc(C(=O)O)c1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(C)(C)Oc4c3ccc(Cl)c4F)cc21 +O=C(O)c1sc(-c2ccccc2)cc1-c1conc1-c1ccc(Cl)cc1 +CC(C)(O)c1coc(Cn2ncc(NC(=O)c3ncoc3-c3ccc(F)cc3)n2)n1 +Cc1nnc2c(NC3CCN(C)CC3)cc(N(C)Cc3ccccc3)nn12 +CCCn1c(=O)c2nc(-c3ccc(S(=O)(=O)NCCN(C)C)cc3)[nH]c2n(CCC)c1=O +CN(C)c1ccc(-c2cc(-c3ccc(N)cc3)[se+]c(-c3ccc(N4CCOCC4)cc3)c2)cc1 +O=C(CCCCCCNC(=O)c1ccc(C(O)(c2cccc(F)c2)c2cccc(F)c2)cc1)NO +Oc1ncnc2c(C3OC(CI)C(O)C3O)c[nH]c12 +COc1cc(C2C(C#N)=C(N)Oc3cc(N(C)C)ccc32)cc(OC)c1OC +Cc1ccc(N2CCN(C(=O)C3C(c4ccc(Cl)cc4)CCN3C(=O)C(C)(C)C)CC2)c(C(N)C(C)C)c1 +COC(O)=C1C(C)=NC(C)=C(C(=O)OCCCN2C(=O)c3ccccc3S2(=O)=O)C1c1cccc(Cl)c1Cl +CCCc1c(OCCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1Oc1ccccc1C(=O)O +CCCOc1cc(CN)cc2[nH]c(=O)c3c(c12)NCCC3 +O=C(Nc1ccc(C(=O)N2CC3COCC3C2)cc1)N1Cc2ccccc2C1 +CC1CCNC(=O)c2cc3ccc(C(=O)Nc4cnn(C)c4)cc3n21 +O=C(O)CCCC(O)C=CC=CC=CC(O)CC=CCCCCC(F)(F)F +CN(C)c1ccc(F)c(CCNC(=O)Nc2ccc(Br)cn2)c1F +CCc1nn(C2CCCC2)c2c1CCn1c(-c3ccccc3C)nnc1-2 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+CC(C)(C)OC(=O)Cc1nc(-c2ccc3[nH]c4c5c(c6c(c4c3c2)C(=O)NC6=O)CCC5)cs1 +O=C(NCc1ccc(C(F)(F)F)cc1)C1CCOc2ncccc21 +CCCCCc1cc2c(c3c1CCCO3)C1CC=CCC1C(C)(C)O2 +COc1ccc(Nc2nc3c(N4CCS(=O)(=O)CC4)cccn3n2)cc1 +O=C1N(c2ccc3sc(Cl)cc3c2)CCN1c1cnccc1C1CC1 +O=C(NCc1nc2ccccc2[nH]1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 +O=C(NCc1ccc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cn1)c1cnc2nccn2c1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(COC3CCCC3O)c12 +O=C(CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1)Nc1ccccc1Cl +CC(C)Nc1ncc2c(n1)CN(C(=O)NC(c1ccc(F)c(Cl)c1)C(C)O)CC2 +CC1(C)CC=C(C#Cc2ccccc2)c2cc(C=Cc3ccc(C(=O)O)cc3)ccc21 +O=C(NC1CC1)c1ccc(-c2cnc3c(NCC4CCOCC4)nccn23)cc1 +CN(C)CCCn1c(CN(C)C2CCCc3cccnc32)nc2ccccc21 +CN(C)CCNc1ccc2ncnc3c2c1C(=O)c1ccccc1-3 +COCc1cc(COc2c(C)cccc2-c2cccc(N3CCC(C(=O)O)C(OC)C3)n2)cc2c1CN(C1CCOC1)CC2 +CC1C(c2ccccc2)C1(NS(=O)(=O)c1cc2nn3cc(Cl)ccc3c2s1)C(=O)O +O=C(Nc1nc(-c2ccc(F)cc2)cs1)C(Cc1cscn1)NC(=O)C1OC1C(=O)O +CCCCCCCCN1C2CCC1CC(NC(=O)c1cc3ccccc3n(C(C)C)c1=O)C2 +NC1=NC2CCC(NC(=O)c3cccc(Cl)c3)CC2CS1 +CC1CNCCN1c1cc(=O)n(C)c(CCc2ccccc2C(F)(F)F)n1 +Cc1ccc(C=CCN(C)Cc2ccc3c(c2)CCCCC3)cc1 +N=C(N)c1cccc(CN2CCC(NS(=O)(=O)c3cc4cccnc4s3)C2=O)c1 +Cc1cc(C)n2nc(C(C#N)=Cc3ccccn3)c(C#N)c2n1 +O=S(=O)(N1CCOCC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +CCN(c1cccc(C(=O)NCC(O)CN2CCc3ccccc3C2)c1C)C1CCOCC1 +N=C(Nc1ccc(Oc2ccc(NC(=N)c3ccccn3)cc2)cc1)c1ccccn1 +O=C1Cc2c(cccc2Oc2ccc(Nc3ncnc4ccn(CCO)c34)cc2Cl)N1 +CC(C)CNc1ccc2cc(C#N)c3nc4ccccc4n3c2c1 +Cc1nnc(Sc2sc(-c3cc[nH]n3)c3c2C(=O)CC(C)(C)C3)s1 +CCCC1NC(=O)c2[nH]c3ccccc3c2-c2ccccc21 +CCC(CC=NOCCN)C1(C)CCC2C(CCC3CC(O)CCC32C)C1=O +COc1ccc(CNC(=O)c2ccc(C(=O)C(F)(F)F)s2)cc1 +Cc1ccc(NC(=O)Nc2cccc(C#Cc3cncc(C(=O)N=S(C)(C)=O)c3)c2)cc1 +COc1cc2c(cc1OC(C)CN(C)C)Cc1c-2n[nH]c1-c1ccc(-c2ccc(O)cc2)cc1 +COC(=O)C(Cn1ccc2ccccc21)NC(=O)C(CC(=O)O)N1CCC(NC(=O)Cc2ccc(C(=N)N)cc2)C1=O +CCCCCCCCc1nc(-c2ccc(CNC(=O)C3NCCC3O)cc2)no1 +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2cccnc2)sc2ccccc12 +N=C(N)NN=Cc1ccc(Cl)c([N+](=O)[O-])c1 +COc1c(CO)cccc1-c1cc2c(NC(C)c3ccccc3)ncnc2s1 +O=C(CCCC1CCNCC1)Nc1nc2ccc(C(=O)c3ccccc3)cc2[nH]1 +Cc1nn(Cc2ccccc2)c(=O)c2nc(C)n3nc(-c4ccc(Cl)cc4)cc3c12 +COc1ccccc1N1CCN(CCC=C2CCCc3ccccc32)CC1 +O=C(CCN1CCCC1)Nc1ccc2c(NCc3cccnc3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nnc(Nc2ccc(F)c(F)c2)o1 +COc1cccc(-c2cc(N3CCN(C)CC3)nc(N)n2)c1 +Cc1nccc2c1[nH]c1cc(OCCN3CCOCC3)ccc12 +N#Cc1ccc(C2CN3CCCC3c3cc(OCCCN4CCCCC4)ccc32)cc1 +O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2cc(Cl)cc(Cl)c2)CC1 +c1ccc(C(c2ccccc2)C2CCC(NCc3cccs3)CN2)cc1 +FC(F)(F)c1cc(-c2cccnc2Oc2ccc(Cc3nc4ccccc4[nH]3)cc2)ccn1 +Cc1[nH]c2c(c1C)CC1(O)C3Cc4ccc(O)c5c4C1(CCN3CC1CC1)C2O5 +O=C(O)c1[nH]c2cc(Cl)cc(Cl)c2c1CN1CC(=O)N(c2ccccc2)C1=O +COc1ccc2c(c1)OCC=CCCCCN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +CN1C(=O)C(NC(=O)Nc2cccc(CC(=O)O)c2)N=C(c2ccccc2)c2ccccc21 +Cc1ccc(-c2nc(SCC3CC(C)(O)CC(=O)O3)[nH]c2-c2ccc(C)cc2)cc1 +COC(=O)CNC(=O)C(=O)c1cn(S(=O)(=O)c2ccc(C)cc2)c2ccccc12 +CNC(=O)c1ccc(-c2c[nH]c(C(Cc3ccccc3)NC(=O)C3CCC(CN)CC3)n2)cc1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCC3CNC(=O)O3)c12 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C(Cc1ccccc1)NCP(=O)(O)O +CC(C)(C(=O)O)N1CCC(c2cc(-c3ccc(F)cc3Cl)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c2)CC1 +O=S(=O)(c1ccccc1)c1cc(Nc2cc(-c3ccc(OC(F)(F)F)cc3)[nH]n2)nc(NC2CCC(O)CC2)c1 +CCCC(C)Oc1cccc(C(C)NS(=O)(=O)CCCOCn2ccc(=O)[nH]c2=O)c1 +O=C(c1cc2ccccc2[nH]1)c1cc2c(Nc3ccc(F)cc3)ncnc2s1 +CNCc1ccccc1N1CCC(NC(=O)c2cc(C(F)(F)F)nn2-c2ccc3onc(N)c3c2)CC1 +CC(C)Oc1ccc(NC(=O)C2CC3CCC2N(S(=O)(=O)c2ccsc2)C3)cc1 +CN(C)C(=O)C(c1ccc(-c2ccn3nccc3n2)cc1)C(N)C(=O)N1CCC(F)C1 +CCN(c1ccc2ncc(-c3cnn(C)c3)nc2c1)c1cc(OC)cc(OC)c1Cl +COC1Cc2cc(-c3ccc(C#N)cc3)sc2C2(CCN(Cc3ccccc3)CC2)O1 +CCc1nc2ccccc2n1C1CCN(C(=O)c2cc3cc(OC)ccc3[nH]2)C1 +CC(CSC(=O)c1ccccc1)C(=O)N1CC(Sc2ccccc2)CC1C(=O)O +COCCOc1ccc(N2CCN(CCCCc3c[nH]c4ccc(OC)cc34)CC2)cc1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCN2CCOCC2)CCCC1)c1cc2c(Cl)cccc2s1 +O=C(CC1CCCO1)N1CCC(CCCCNC(=O)N2Cc3ccncc3C2)CC1 +CC(C)(CCOCC(O)CO)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2[nH]1 +O=C(NCc1ccc(C(=O)OCN2C(=O)c3ccccc3S2(=O)=O)cc1)Nc1ccccc1 +O=C(C1CCCN1C(=O)CCCC1Cc2ccccc2C1)N1CCCC1 +Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc(C(CC(=O)O)c2ncco2)cc1 +CC(C(=O)O)c1ccc2c(c1)N(CCCN1CCCN(c3cc(=O)n(C)c(=O)n3C)CC1)c1ccccc1S2 +COc1ccc(-c2c3cc4c(cc3cc(=O)n2NC(=O)Nc2ccc(SC)cc2)OCO4)cc1 +CNS(=O)(=O)CCNC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 +NC(=O)CC(NC(=O)c1cccc(-c2ccc(Oc3ccc(F)cc3)cc2)n1)C(N)=O +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)NC3CCCC3)s2)nn1 +Cc1c(CSc2ccccc2)oc2cccc(OCCCNCc3cccnc3)c12 +Cn1cc(-c2cc3c(-c4cccc(N5CC(N)CC(F)C5)n4)n[nH]c3cn2)cn1 +COCCn1cccc1C(OC)(c1ccc(N(C)S(=O)(=O)c2ccccc2)cc1)C(F)(F)F +C#Cc1cccc(Nc2ccnc3cc(OC)c(OC)cc23)c1 +COCCNC(=O)c1ccc(OC2CCN(Cc3ccc(F)c(F)c3)CC2)c(Cl)c1 +O=C(C(O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(n2cc[nH]c2=O)CC1 +CCC(=O)c1ccc2c(c1)sc(=O)n2CCCCCCN1CCCCCC1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CN(C(=O)OCCF)C1 +COc1ccc(-c2ccccc2C(=O)Nc2ccc(C(=O)N3CC4COCCN4Cc4ccccc43)c(Cl)c2)cc1 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1(S(=O)(=O)c2ccccc2)CCCC1 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+COc1cc(-c2cc3c(ccc[n+]3[O-])c(OC(C)C3CNC(=O)C3)n2)cc(Cl)c1OC +CN1CCN(CCCNc2ncc3cc(-c4c(Cl)cccc4Cl)c(NC(=O)Nc4ccc(C(F)(F)F)cc4)nc3n2)CC1 +c1ccc(CN2CCN(CCCc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)nc1 +CC(C)Sc1sc(C(=O)O)c(-c2ccc(Cl)cc2)c1C#N +Cc1ccc(-c2ncccn2)c(C(=O)N2CC(COc3ccc(F)cn3)CCCC2C)c1 +Cc1c(Cl)cccc1NCc1cnc2nc(N)nc(N)c2c1C +CCCc1c(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)nnn1Cc1ccccc1 +COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(C)=O)cc1 +CCCCc1cc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)cc1COc1cccnc1 +Nc1ccc(F)cc1NC(=O)c1cnc2cc(N3CCNCC3)ccc2c1 +Cc1cc(-c2nc(-c3ccc(OC4CC4)c(C)c3)n3c2CCOC(C)C3)cc(C)n1 +COCC(C)NC1CCC(Nc2cc(-c3nc(NCC4CCOCC4)ccc3C(F)(F)F)c(Cl)cn2)CC1 +c1ccc2c(-c3cnn4cc(-c5ccc(N6CCOCC6)cc5)cnc34)csc2c1 +O=C(COc1ccc(OCCCCCc2ccco2)cc1)COc1ccc(C(=O)O)cc1 +CN1CCCC(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)C1 +O=C(O)CCn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2ccccc21 +CCNC(=O)N1CCCC(Nc2ncc(Cl)c(-c3c[nH]c4ccccc34)n2)C1 +COc1ccc2c(c1)C(=O)N(c1ccc(N3CCCCC3=O)cc1)CN2C(=O)Cc1cccc(Cl)c1 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+CC(C)C(CC(O)C(N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NC1CCCCC1 +COc1ccc(-n2nccn2)c(C(=O)N2CCC3CN(c4cc(C)ccn4)C3C2)c1 +O=C(O)COc1cccc2c1CCC(Cn1cc(C(c3ccccc3)c3ccccc3)ccc1=O)C2 +CN1CCC(NC(=O)Nc2ccc(C#N)cc2)CC1c1nc2ccccc2[nH]1 +Cc1cc(C)c(-c2[nH]nc(CC(F)(F)F)c2C)cc1C(=O)N1CC(c2ccc(C#N)cc2)C1 +Cc1ccc(F)c(-c2cc(F)cc(C(CC(=O)O)c3ncco3)c2)c1 +Cn1cc(-c2cc(NS(=O)(=O)CC(F)(F)F)ccc2Oc2ccccc2)c2cc[nH]c2c1=O +CN(C)CCN1Cc2n[nH]c(=O)c3cccc4[nH]c(c2c43)C1 +COc1ccc(Cl)c(C(=O)NCC2(c3ccc(F)nc3)CCC(F)(F)CC2)c1 +CCc1ncnc(N2CCC(CCO)CC2)c1C#Cc1ccc(C)nc1 +O=C(O)CC1(Cc2ccccc2)C2CC3CC(C2)CC1C3 +CN1CCN(c2ccc(Nc3ncc(Cl)c(NCC4CCCO4)n3)cc2)CC1 +CCOc1ccc(-c2ccc(=O)n(-c3ccc(S(N)(=O)=O)cc3)n2)cc1 +COC(C)(C)CCn1nc(Nc2c(C)cc(C)cc2C)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21 +Cn1nc(-c2ccc(OC3CCN(C4CCCC4)CC3)nc2)ccc1=O +CN(Cc1cccc2ccccc12)C(=O)C(Cc1ccccc1)NC(=O)C1CCCN1C(S)=NCc1ccccc1Cl +CCN(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(S(=O)(=O)c2ccc3cn[nH]c3c2)CC1 +Cc1n[nH]c2ccc(-c3cncc(OCCC(N)Cc4ccccc4)c3)cc12 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+O=S(=O)(NCC1CC2(c3ccc(F)cc3)NC1CCC2NCc1cc(OC(F)(F)F)ccc1OC1CC1)c1ccccc1 +CC(=O)Nc1nc(-c2ccccc2)c(-c2noc(C)n2)s1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NC2CC2)CCCCC1)c1cc2ccccc2s1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)cc1C(=O)NCCCN1CCCC1 +N#Cc1ccc(N2CCOc3cc(S(=O)(=O)Nc4nccs4)ccc32)cc1 +Cc1ccc(-c2ccc(COC(=O)NC3C(=O)OC3C)cc2)cc1 +c1cn(-c2ccc(-c3ccnc(Nc4ccc5ncsc5c4)n3)cc2)cn1 +Cn1nc(C(C)(C)C)c(Cl)c1-c1nc2cc(-c3ccccc3Cl)nc(OCCN3CCOCC3)c2[nH]1 +N#Cc1c(-c2cc(Cl)c3c(ccn3CC3CC3)c2)ccn2c(CC(F)(F)F)cnc12 +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1CC2CCC1(C)C2(C)C)C(=O)NC(CO)Cc1ccccc1 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3ccc(N)c(F)c3)C2O)c1 +C#CCN(Cc1ccc2nc(N)nc(N)c2n1)c1ccc(C(C)=O)cc1 +Oc1ccc2c3c1OC1c4nc5ccccc5cc4CC4C(C2)N(CC2CC2)CCC314 +COC(=O)CCc1ccc(Oc2cc3cc(-c4ccc(C(F)(F)F)cn4)[nH]c3cc2C2CCC(=O)N2C)cc1 +CN1C(=O)c2ccccc2SSc2ccccc2NC(=O)C(CC(=O)O)NC(=O)CNC(=O)C1CCCN=C(N)N +O=C(NCc1cccc(Cl)c1)c1cncc2nnc(-c3ccc(OC(F)F)cc3)n12 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CO)c4cccc5cc[nH]c45)ncc23)ccn1 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+NS(=O)(=O)c1cc2c(s1)CC(O)CS2(=O)=O +CC(C)CCn1c(Cn2c(=O)n(CC(=O)OC(C)(C)C)c3ccccc32)nc2cc(C(=N)N)ccc21 +COc1cccc(CCC(NC(Cc2ccc3c(c2)oc2ccccc23)C(=O)O)P(=O)(O)O)c1OC +NC(=O)c1nn(-c2ccccc2)c2c1CCc1cnc(NC3CCCC3)nc1-2 +c1ccc(Nc2nc3cnc(Nc4ccc(N5CCOCC5)cc4)nc3n2C2CCCC2)cc1 +NC1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccnc5)c4)c23)CC1 +CCCCCN(CCCCC)C(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1ccc2ccccc2c1 +CN1C(=O)C2CN(Cc3c2c2ccccc2n3Cc2ccc(C(=O)NO)cc2)C1=S +O=C(CC(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)C(=O)NC1c2ccccc2CC1O)NO +CN1CC(C(=O)NCc2cccc(C(F)(F)F)c2Cl)NC1=O +CCc1ncnc(-c2cc(Cl)c(C(=O)N3CCC(C(C)O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCC(c5ccccc5)CC4)nc3n2)cc1CO +COc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1cncc(-c3cnccc3C)c1)CC2 +CCCOc1cc(CN2CCOCC2)cc2[nH]c(=O)c3c(c12)NCCC3 +CCOC(=O)c1ccc(NC(=O)Cn2ncc(Cl)c(Cl)c2=O)cc1 +CNCc1cc(NC(=O)Nc2cccc3c2C2CCCN2C3=O)[nH]n1 +Cc1noc(C)c1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 +O=C(NC(Cc1ccccc1)C(O)CN(CCN1CCCC1)C(=O)c1ccc2nc(N3CCCC3)oc2c1)OCc1cncs1 +COc1ccc2c(c1)C(=O)c1ccc(Nc3cc(F)cc(F)c3F)cc1CC2 +CCN(CCc1ccc(Cl)cc1)C(=O)C1CCN(CCCN(C(=O)C2CCN(C(C)=O)CC2)c2cccc(Cl)c2)CC1 +Cc1ccc(CN2CCOCC2)cc1NC(=O)c1ccc(Nc2ncc(C)c(-c3ccccc3)n2)cc1 +Cn1cc2c(nc(N)n3nc(-c4ccc([N+](=O)[O-])cc4)nc23)n1 +Cc1ccccc1Cc1cc2c(N(C)c3cccc(Br)c3)nc(N)nc2[nH]1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCCCC2)cc1 +CCCc1nc2c(C)cc(C(=O)NCCc3ccccc3F)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(NC1(c2ccccc2)CCC1)C1CCCC1c1cc(-c2ccc(C(F)(F)F)cc2O)on1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(COC(=O)C(C)N)cccc4n3)c(C)c12 +N#CCc1cc(O)cc2cc(-c3ccc(O)cc3)oc12 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(-c3ccc4c(c3)OCO4)nc2)cc1 +Cn1nccc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2ccc(F)cn2)cc1Cl +O=c1ccc2ncc(F)cc2n1CCN1CCC(NC(=S)Nc2ccc([N+](=O)[O-])cc2)CC1 +CN1CCN(Cc2ccc(-c3nc4c(C(N)=O)cccc4[nH]3)cc2)CC1 +COc1ccc(CNC(=O)c2ccc(NC(C)=O)cc2)c(C(F)(F)F)c1 +COc1ccc(C(=O)NCc2cccc(C(=O)Nc3ccc(CN(C)C)cc3)c2)cc1Cl +Cc1nc(-c2cc(Cl)ccc2Cl)n2c1nnc1ccc(Cl)cc12 +Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCCCNc1c3c(nc4cc(Cl)ccc14)CCCC3)O2 +O=C(CCCCCCNC(=O)c1c[nH]c2ccccc12)NO +CC(C)(C)c1ccc(C(=O)NNc2c(Cl)cccc2Cl)cc1 +CN1CCC(N(C)C(=O)N2CCC(N(C)C(=O)c3ccc(-c4cccc(Cl)c4)s3)C2)C1 +CC(C)n1c(Nc2ccccc2)nc2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3)nc21 +COc1cc(CC(=O)Nc2nc3ccc(OC(F)(F)F)cc3s2)cc(OC)c1OC +OCc1ccc2c(c1)nc(Nc1cccc(Cl)c1)c1ccncc12 +CC1=C(Sc2cccc(F)c2)C(COCCO)C(=O)NC1=O +O=C(NCC1Cc2ccccc2CN1C(=S)NCC1CCCN1Cc1ccccn1)Nc1ccccc1 +COc1ccc(-n2nc(CC(C(=O)O)c3ccc(Cl)cc3)cc2-c2ccc(Cl)cc2)cc1 +CC1CCC(COc2ccc(F)cn2)CN1C(=O)c1cc(F)ccc1-n1nccn1 +CC(Nc1nccc(N2C(=O)OCC2(C)c2ccc(F)cc2)n1)c1ccc(Oc2ccccc2)cc1 +COc1cc(Cl)ccc1-c1ncnc2cc(S(=O)(=O)Nc3ncns3)ccc12 +CCCCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2 +COc1ccccc1N1CCN(CCCCCCn2ncc(N3CCN(CC4COc5ccccc5O4)CC3)c(Cl)c2=O)CC1 +CC(C)Oc1ccc(Nc2cc(=O)n(CCCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +COC(=O)CC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)C2C(N3CCCC3)CCCC21 +CC1(CS(=O)(=O)N2CCC(Oc3ccc(OCc4cccc(C#N)c4)cc3)CC2)NC(=O)NC1=O +CN(c1ncccc1CNc1c(C(F)(F)F)cnc2[nH]c(-c3ccc(F)cc3)cc12)S(C)(=O)=O +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CNC1)C2c1ccc(Sc2nc3cccc(Cl)c3[nH]2)o1 +CC(C)CN(NC(=O)c1ccc(CN2CCN(C)CC2)o1)c1nc(C#N)ncc1Br +CC(C)Cc1nc2ccc(OCC(N)=O)cc2c(-c2ccc(F)cc2)c1CN +c1cc(-c2c[nH]c3ccc(-c4nncs4)cc23)nc(N2CCOCC2)c1 +O=C(CCN1CCC(c2ncccn2)CC1)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1 +CC(C)c1cccc(C(C)C)c1NS(=O)(=O)NCC1(c2ccccc2)CCCC1 +CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CCC(O)C3)c(Cc3ccnc4ccccc34)sc21 +CC(=O)Nc1c2ccccc2c2c3c(cccc13)C(=O)C(CCN(C)C)C2=O +CC1=C(c2ncnn2C2CCC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C(F)(F)F)cc2N1 +Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cccc(F)c2)C(N2CCC2)CC3)c1 +OC1(c2ccccc2Cl)CCN(Cc2c[nH]c3ccccc23)CC1 +Cc1c(Cn2c3ccccc3n3c(=O)cc(N4CCOCC4)nc23)cccc1C(F)(F)F +Cc1cc(C)c(Nc2nc(N)nc(NC3CCN(Cc4ccncc4)CC3)n2)c(C)c1 +CCC(CO)Nc1nc(Nc2cc(Cl)cc(C(=O)O)c2)c2ncn(C(C)C)c2n1 +CCc1c(C(=O)C(N)=O)c2c(OC)cc3ccccc3c2n1Cc1ccccc1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(NCC3CCO3)c2n1 +CCC(=O)C(c1ccc(O)cc1)C1CCN(CCc2ccccc2)CC1 +Cc1onc(-c2ccc(F)c(F)c2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 +CN1CCN(c2cccc(Nc3nc4c(-c5cccc(S(C)(=O)=O)c5)cccn4n3)c2)CC1 +CN(CCN)c1nc(-c2ccncc2)nc2sc3c(c12)CCCC3 +COCC(C)Oc1cc(CCc2ccccc2OC)cc(C(=O)Nc2ccn(C)n2)c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(NS(=O)(=O)c4ccc(C)cc4)c(C)c3)ncc2Cl)c1 +NS(=O)(=O)NCCNc1nonc1C(=NO)NCc1cc(Br)co1 +CCC1(CC)Oc2nc(NC(=O)C(C)NC)ccc2N(c2ccc(Cl)cc2)C1=O +CNc1ncnc2c1ncn2C1OC(C(=O)O)C(O)C1O +COc1ccc(Cn2c(CCc3ccccc3)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 +CCCCCC(O)(C#CC1(OC)CN2CCC1CC2)c1ccccc1 +CCOc1cc(=O)n(C)cc1-c1cc(NCc2ccc(Oc3ccccc3)cc2)ccc1Oc1ccc(F)cc1F +COc1cccc(OC)c1-c1cccc(C(CC(=O)O)c2ncc(C)s2)c1 +COCCn1cc(-c2ccc(-c3c4c(nn3C)CC(C)c3cnc(Nc5ccn(C)n5)nc3-4)cc2)cn1 +CCOC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(C)cc1Cl +O=C(NC1CC1c1ccccc1)N1CCC(n2cncn2)CC1 +CCC1CCC(Sc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +N=C(N)NCCCC(NC(=O)CN1CCCCC(NS(=O)(=O)Cc2ccccc2)C1=O)C(=O)c1nccs1 +CCOc1ccc2c(c1Cl)CCN(Cc1ccc(C(C)NC(C)=O)cc1)C2 +CC(C)(SCCCc1ccccc1)C(N)C(=O)N1CC(F)CC1C#N 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+Clc1ccc2c(Nc3ccc(Nc4nc(NCCCN5CCOCC5)nc(Nc5ccccc5)n4)cc3)ccnc2c1 +N#Cc1cc(-c2nc(Nc3ccc(CN4CCOCC4)nc3)ncc2F)cnc1N1CCC(F)C1 +CC1C2c3cc(N4CCOCC4)ccc3CC(c3ccc(N4CCOCC4)cc32)N1C +O=C(C=Cc1cccn(CC=Cc2cccc(Br)c2)c1=O)NO +CCNC(=O)NCC1CC1c1c(Cl)ccc2c1CC(CCCCc1ccccc1)O2 +COc1cccc(Nc2c(C(N)=O)cnc3ccc(S(=O)(=O)c4ccc(C(C)(C)C)cc4)cc23)c1 +O=S(=O)(c1ccc(C(F)(F)F)nc1)N1C(C2CC2)c2cn[nH]c2C(F)(F)C12CC2 +Nc1nc(NC(=O)CCCC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1ccc(C(C(=O)NCCCN2CCC(C#N)(c3ccccc3)CC2)c2ccc(C)cc2)cc1 +CCCCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +Oc1cccc2c1OC1CCCC3CN(CCc4ccccc4)CCC231 +COc1cccc(CCCCN2CCN(c3ccccn3)CC2)c1 +CC1(O)CC(N)(c2ccc(-c3nc4n(c3-c3ccccc3)COc3ccc(-c5ccn[nH]5)cc3-4)cc2)C1 +CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(C(C)(C)CNCC(F)(F)F)cn1 +CCCCNC(=O)c1sc2nc(OC)c(Cl)c(C)c2c1N +CC1CCCC(C)N1CCCNC(=O)C(c1ccccc1Cl)c1ccccc1Cl +Cc1csc2nc(C(C)NC(=O)C=Cc3ccccn3)oc(=O)c12 +CC(c1cc(F)cc(Cl)c1)N(C(=O)c1ccccc1)C(C(N)=O)c1ccccc1 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+COCCNC1CCC(Nc2cc(-c3cccc(NCC4CCOCC4)n3)c(Cl)cn2)CC1 +CC(=O)CCCCCC(NC(=O)C1CCCCN1C)C(=O)NCCc1c(-c2ccccc2)[nH]c2ccccc12 +O=C(O)CCNC(=O)C(CC(=O)NO)Cc1ccccc1 +ON=C1c2ccccc2-c2ccc(OCCN3CCOCC3)cc21 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(N4CCCCC4)cc2)CC3)cc1 +Cn1c(NCC(N)Cc2ccccc2)nc(-c2ccncc2)c(-c2ccc3ccccc3c2)c1=O +Cc1cncc(-c2cc3c(cn2)cnn3-c2ccc3c(n2)CC(CN)CO3)n1 +Cc1cc(C)[n+](CC(=O)Nc2ccc(S(N)(=O)=O)cc2I)c(C)c1 +O=C(C=Cc1ccc2c(c1)nc(CCc1ccccc1)n2CC(O)CO)NO +COC12C=CC3(CC1C(=O)NCCCCCCNC(=O)OC(C)(C)C)C1Cc4ccc(O)c5c4C3(CCN1C)C2O5 +Cc1nc(NC(=O)N2CCCC2C(N)=O)sc1-c1ccnc(C(C)(C)C)n1 +Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCCCC2)CC1 +COc1ccccc1-c1ccc(CC(NC(=O)C2(S(=O)(=O)c3ccccc3)CCOCC2)C(=O)O)cc1 +Cc1ccc(C(=O)C=Cc2ccc(C=CC(=O)NO)o2)cc1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C#N +CCc1cccc(NC(=O)C2CCCN2C(=O)Nc2cn(C(N)=O)c3ccccc23)n1 +COC(=O)C(Cc1ccccc1)NC(=O)c1c(C)n(CCN2CCOCC2)c2c(OC)cccc12 +COc1ccccc1S(=O)(=O)Oc1cc(C)cc(OCCC=NN=C(N)N)c1 +O=C(Cc1ccccc1)NC(=S)Nc1ccc(Oc2ccnc3ccsc23)cc1 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+O=C(O)C1CN(Cc2ccc(-c3noc(-c4cnn(CC5CC5)c4-c4ccncc4)n3)cc2)C1 +CCC(C)Sc1c(C#N)c(C(F)(F)F)nn1-c1ccc(S(C)(=O)=O)cn1 +CC1(C)C2CC3OB(C(CCCCN)NC(=O)Cn4nc(CS(C)(=O)=O)nc4Cc4ccccc4)OC3(C)C1C2 +CN(C)S(=O)(=O)NCC1CCC(NC(=O)CN2C(=O)CCSc3ccccc32)CC1 +O=C(O)c1ccc(CN(Cc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 +CCCc1nc(-n2cccc2C(=O)C(F)(F)F)c(C#N)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN(C)C(=N)c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c(N2CCCCC2)c1 +O=C(Cc1ccc(O)cc1)NN=C1C(=O)Nc2ccccc21 +Cn1c(N2CCCN(CCC=C3c4ccccc4COc4ccc(CC(=O)O)cc43)CC2)cc(=O)n(C)c1=O +CC1(C)CN(C(=O)CC#N)C12CCN(c1ncnc3[nH]ccc13)C2 +Cc1nc(-c2cn3c(n2)-c2cnc(N4CCCC4C4CCCCN4C)cc2OCC3)n(CC(F)(F)F)n1 +OCC1CCCN1CCc1c[nH]c2ccc(-c3cccs3)cc12 +COC(C)C1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +CN(c1cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CC2)cc(C(=O)C2CCCCC2)c1)S(C)(=O)=O +CNCCc1cc(C#N)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 +COC(=O)c1ccc(NC(=O)C(CC(C)C)NC(=O)C(CC(=O)NO)CC(C)C)cc1 +CCOC(=O)C(=O)C=C(O)c1ccc2c(c1)c(=O)c(C(O)=CC(=O)C(=O)OCC)cn2Cc1ccc(F)cc1 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+O=C(CNCCn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1)OC1CCCC1 +Nc1nc(N)nc(NCCc2ccc(S(N)(=O)=O)cc2)n1 +CCC(COc1cc(Cl)cc(Cl)c1)OC(=O)NCc1ccccc1 +CCSC1=NS(=O)(=O)c2cc(C)cnc2N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COCCC(CC1(C(=O)Nc2nnc(Cc3ccccc3)s2)CCCC1)C(=O)O +O=C(Nc1ccc(N2CCC(N3CCCCC3)CC2)c(Cl)c1)C1(c2ccccc2)CCC1 +CC1(C)CC(=O)N(c2cc(Cc3nnc(O)c4ccccc34)ccc2F)C1=O +CNC(C)C(=O)NC1CC=CCC2C(Cc3ccccc3)CC(C(=O)NC3CCCc4ccccc43)N2C1=O +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc4c(c3)CC(=O)N4)nc2n1 +COc1cc2c(c(OC)c1OC)CC(Sc1nc3ccccc3[nH]1)C2=NN=C(N)N +O=C(Cn1c2ccccc2c(=O)c2ccc(Cl)cc21)Nc1cccc(Cl)c1 +NC(C(=O)N1CCCC1C(=O)NCc1cccc(O)c1)C(c1ccccc1)c1ccccc1 +CCc1c(COc2ccc(Cc3nnn[nH]3)cc2)ccc(C(C)=O)c1O +CCCCC1=NS(=O)(=O)c2ccccc2N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cc1ccccc1C(=O)N(C(=S)OCCN1C(=O)c2ccccc2C1=O)c1ccc(Cl)cc1 +O=c1cc(C2CCNC(CCc3ccccc3)C2)o[nH]1 +CCN1CCN(C2(C(=O)N3CC(S(=O)(=O)c4ccccc4Cl)CC3C(=O)NC3(C#N)CC3)CC2)CC1 +Cc1cc(N2CCN(CCCO)CC2)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 +CCCCCCCCCCC(C)(C)C(=O)Nc1c(OC)ccc2c(=O)ccoc12 +C#CCn1c(=O)c2c(nc(C=Cc3ccc(OC)c(OC)c3)n2C)n(C)c1=O +CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCN(C)C3CCCCC3)cc2C1=[N+](C)[O-] +CCC(CC)(Cc1nc2ccc(OCc3ccc(C)cn3)cc2n1Cc1ccc(OC(F)(F)F)c(Cl)c1)C(=O)O +COC(=O)C(CCCC(=O)NO)NC(=O)CCCCC(=O)Nc1ccccc1 +NS(=O)(=O)c1ccc(CNS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc1 +CC1(c2cc(NC(=O)c3ccn(C(F)F)n3)ccc2F)N=C(N)OCC1(F)F +Cn1nc(C(=O)N2CCOCC2)c2c1-c1cccc(F)c1S(=O)(=O)C2 +O=C(O)C(O)=CC(=O)c1ccccc1OCc1ccc(Cl)cc1 +COc1cnc(-c2ccc(NC(=O)Nc3ccc(N4CCN(S(C)(=O)=O)CC4)cc3)cc2)nc1N1CCOCC1 +O=[N+]([O-])c1cn2c(n1)OC(COc1ccc(-c3ccc(F)cc3)cn1)CC2 +NCCCC(NC(=O)OCc1ccccc1)C(=O)N1CCCC1 +O=C(c1cc2cc(Nc3nccc(-c4cc(OC5CCOCC5)ccn4)n3)ccc2[nH]1)N1CCOCC1 +FC(F)(F)c1cccc(NC(=S)N2CCCC2c2ccccc2Cl)c1 +Cn1cc(-c2cc(Oc3ccc(NC(=O)N4CCN(c5ccc(F)cc5)C4=O)nc3)ccn2)cn1 +Cc1ccc(CN2CCC(N3CC(c4ccc(O)cc4)C3)C2=O)cc1F +CCOc1ccc(C2c3[nH]c4ccccc4c3CC3C(=O)N(C4CCCCC4)C(=O)N32)cc1 +COc1ccc2[nH]c(-c3n[nH]c4ccccc34)cc2c1 +Cc1ccc2cc(-c3n[nH]c4ccc(NC(=O)c5ccco5)cc34)[nH]c2c1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccccc3F)CC2)nc2ccsc12 +CCCc1cc(N2CCC(O)CC2)nc2sc(C(N)=O)c(N)c12 +O=C(OCC#CCSc1nnc(-c2cccc3ccccc23)o1)C1CC1 +CC(NCCNc1ccnc2cc(Cl)ccc12)c1nc(Cc2ccccc2)c(N2CCOCC2)o1 +CC(C=CC(=O)NO)=Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 +CC(C)(C)c1ccc(C(=O)Nc2ccc3sc(CO)nc3c2)cc1 +CC(C)(CCCCOc1cc(-c2ccc(Cl)cc2)c2ccccc2n1)c1nnn[nH]1 +CCCCN1CCN(Cc2ccc(-c3ccccc3)cc2)C(CCO)C1 +CN(C(=O)Cc1ccccc1)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 +NCc1ccc(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(Cl)c(O)c(Cl)c4)cc23)cc1 +NCC1CCC(C(=O)NC(Cc2ccccc2)c2nc(-c3ccc(C(N)=O)cc3)c(Br)[nH]2)CC1 +CCCCc1nc(C)n(Cc2sccc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C1CCC2=C1C(c1ccc(F)c(Br)c1)C1=C(O)CSCC1=N2 +Cc1cc(C)n2nc(OCCO)c(S(=O)(=O)c3ccccc3)c2n1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1cccc(F)c1F +CCCc1nc(-c2ccc(Oc3ccc(CC(=O)O)cc3OC)c(NS(=O)(=O)c3ccc(Cl)cc3Cl)c2)n[nH]1 +O=C(NC1CCC(O)CC1)C1NC2(CCCCC2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(Cl)c1F +CCCCCCCOc1ccc(NC(=O)ON=Cc2ccc(F)cc2)cc1 +Cc1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1)=NC2 +CNc1ccc(Nc2nccc(-c3sc(C)nc3C)n2)cc1 +CCCN(CC1CC1)C(=O)c1c(C)nc2n(-c3c(C)cc(C)cc3C)c(Cl)cn12 +Cc1ccc(C2=C(n3cnnc3C)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +NCC(Cc1cccc(F)c1)NC(=O)c1cc(Br)c(-c2ccnc3[nH]ccc23)s1 +CC1CCCCN1CCCNc1ncc(C(=O)NCc2ccccc2)c(NCC2CCCCC2)n1 +CNC(=O)c1cccc(Nc2nccc(N3CC(Oc4ccc(F)cc4)C3)n2)c1 +O=C(NCc1ccccc1)NC12CC3CC(CC(C3)C1)C2 +COc1cccc(C(=O)c2cc(C(=O)C(F)(F)F)n(-c3cnn(O)c3)c2)c1 +Brc1ccc(Br)c2c1C1CC(c3ccoc3)(c3ccoc3)C2c2cccc[n+]21 +Cc1noc(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 +C=COC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)CCCCCNC(=O)OCc1ccccc1)C(C)C +CN(C)C=Nc1nn(-c2ccc(C(=O)O)cc2)cc1C#N +CC#CCOc1cccc2c1-c1cccc3c1C(C2)N(CCC)CC3 +Cc1cn(-c2ccnc(Nc3cc(C)c(OCC(=O)N4CCCC4)c(C)c3)n2)cc1CN1CC(O)C1 +CCOc1cc(NS(C)(=O)=O)c(OCC)cc1CNC(=O)Nc1ccc(OC)cc1 +Cc1ccc(C=Cc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4cccs4)cc23)cc1 +CCC(=O)N(Cc1ccc(OC)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 +CC(C)C1C(=O)N(c2ccccc2)C(=O)N1Cc1ccc(C(=O)NO)cc1 +O=P(OC1CCCC1)(c1ccccc1)N1CCCC(c2ccc(Cl)c(Cl)c2)=N1 +Cc1cc(C(=O)N2CCC3(CC2)Cc2cnn(C(C)(C)C)c2C(=O)N3)cc2c[nH]nc12 +Cc1nc(Cc2cccc3ccccc23)c(CCC(=O)O)c(C=O)c1O +Cn1c(-c2c(N)n(C3CCCC3)c3nc4ccccc4nc23)nc2ccccc21 +CC1CCC(NC2=NC(=Cc3c[nH]c4ncccc34)C(=O)N2)CC1 +Cc1cc(C)cc(Oc2c(C(C)C)c(=O)[nH]c(=O)n2CC2CCCCC2)c1 +COc1ccc(Br)cc1CCc1ccccc1-c1nc(C)cn1C +CCOc1ccc(-n2c(C(C)N(Cc3cccnc3)C(=O)Cc3ccc(OC(F)(F)F)cc3)nc3cnccc3c2=O)cc1 +COc1ccc(-c2ccc(N3CCC4CN(C)CC43)cc2)cc1 +CC(C)(O)C(NC(=O)N1CCN(c2ccc(-c3ccccc3)cc2)CC1)C(=O)NO +COc1ccc(Cn2c(C)c(C)c3cc(C(=O)NC(C)c4ccc(C(C)(C)C)cc4)ccc32)cc1OC(C)C(=O)O +O=c1[nH]c2nc(NC3CCOCC3)ncc2cc1Oc1ccc(F)cc1F +CN(CCc1ccc2c(c1)OCO2)C1CCCCC1N1CCCC1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2C)nc1-c1ccccc1F +CC(NS(=O)(=O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1)c1ccccc1CC(=O)O +Cc1ccc(Cl)cc1-n1c(-c2ccccc2)nc(C(=O)O)c1-c1cccc(Cl)c1 +CC(=O)NC1CC2CCC(C1)N2C(=O)c1ccc(Nc2nc(-c3sc(C)nc3C)cs2)nc1 +CC1CN(c2nnc(C(F)(F)F)o2)CCN1c1ncc(OCc2ccc(S(C)(=O)=O)cc2F)cn1 +O=C(CCc1ccc(O)cc1)N(Cc1nc2c(c(=O)[nH]1)COCC2)Cc1cccs1 +CC(=O)Nc1cc(Nc2cc(NC3CC3)n3ncc(C#N)c3n2)c(F)cc1C +C=C(c1ccc(S(=O)(=O)c2ccc(OC)cc2)cc1)C1CCN(C2CCN(C(=O)CCC)CC2)CC1 +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)N4CCNCC4)c4ccc(C)cc34)cc2)c1C +Cc1cc(S(C)(=O)=O)cc2c1N(C(=O)OCCC1CCN(C(=O)OC(C)(C)C)CC1)CC2 +O=C(Cc1ccc(F)cc1)NC(=O)Nc1ccc(Oc2ccnc3[nH]cc(C(=O)CN4CCC(O)C4)c23)c(F)c1 +CN1C2CCC1C(C(=O)OCCc1ccc(N)c(I)c1)C(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3ccc(F)cc3NC(=O)c3cnc4ccccc4c3)cc1)CC2 +O=C(NCCCN1CCOCC1)c1c[nH]c2ccc(S(=O)(=O)N3CCc4ccccc43)cc2c1=O +OCC1CCCN1c1ncnc2sc(Nc3cccc(Br)c3)nc12 +CN1C(=O)CCc2cc(-c3cncc(COc4ncccn4)c3)ccc21 +C=C(CN(C)C)C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)c(C#N)cnc2cc1OCC +CCCC1(CCc2ccc(O)cc2)CC(=O)C(Sc2cc(C)c(N)cc2C(C)(C)C)=C(O)O1 +CN(CCCCN1C(=O)C2Cc3ccccc3CN2C1=O)Cc1ccccc1 +COc1cc2c(N)nc(N3CCN(C(=O)CC(N)c4ccoc4)CC3)nc2c(F)c1OC +CCCS(=O)(=O)N1CCC(CNC(=O)c2ccccc2OC(F)(F)F)(c2ccccn2)CC1 +NC(Cc1c[nH]c2ccccc12)C(=S)N1CCCC1B(O)O +CC(C)Oc1ccc(F)c(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(OC(F)(F)F)c2)c1 +COc1cc(C(=O)NC(C)c2cccc(CN3CCN(C)CC3)c2)ccc1-c1cn[nH]c1 +Cc1ccc(-c2cc(C(=O)OCCOc3ccc4ccc(=O)oc4c3)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 +CC(C)(N)C(=O)N1CCn2c(nc(-c3ccc(F)cc3)c2Nc2ccc(Cl)c(F)c2)C1 +CCC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c1ccccc1 +COc1cc(C(=O)c2ccc(-c3csc(NC(=O)C(N)Cc4ccc(Cl)cc4)n3)cc2-n2cncn2)cc(OC)c1OC +Cc1cn(C2CC(n3cc(Cc4ccccc4)nn3)C(CO)O2)c(=O)[nH]c1=O +CCOC(=O)c1[nH]c2ccc(Cl)cc2c1C(OC)c1ccccc1 +NC(=O)Cn1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21 +COc1cccc(N2CCN(C(=O)c3ccc(C[S+]([O-])c4ccc(Cl)cc4)o3)CC2)c1 +CC1CC2CC(c3cc(F)ccc3F)(S(=O)(=O)c3ccc(Cl)cc3)CCC2NS1(=O)=O +O=C(Cc1ccccc1)Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3ccc4c(c3)CCNC4)n2)c1 +CSc1ccc(Oc2ccc(NS(C)(=O)=O)cc2CN(C)C)cc1F +O=C(O)c1ccc(C(=O)c2ccc(C(=O)c3ccc(Cl)c(Cl)c3)cc2)cc1 +CC(C)n1nccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +O=C(NCC1CCCNC1)c1ccc(O)c2[nH]c(-c3ccccc3)nc12 +CCCN(CCC)CCC1OC2OC3(C)CCC4C(C)CCC(C1C)C24OO3 +O=C(Nc1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cccc([N+](=O)[O-])c1 +CCc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(O)c(O)c3)[nH]c(=O)c12 +CC(C)(C)c1ccccc1N1CCN(C(=O)NCC(=O)O)CC1 +CC(C)(C)OC(=O)NC(C(=O)N1CCCC1C(=O)NC(C=O)CCCN=C(N)N)c1cccc2ccccc12 +Cc1oc(-c2ccccc2)nc1CCOc1cccc(C2CN(C(=O)Oc3ccccc3)CCC2CC(=O)O)c1 +Cc1ccc2nc(NC(=O)CSc3nc4c(c(=O)n3-c3ccccc3)SCC4)sc2c1 +O=c1[nH]ccc(NC2CCC(NCC(F)F)CC2)c1-c1nc2ccccc2[nH]1 +Clc1cc(-c2c[nH]c3ncccc23)nc(NC2CCCCC2)n1 +O=C(O)c1ccc2cc(-c3ccc(CC(O)CO)c(C45CC6CC(CC(C6)C4)C5)c3)ccc2c1 +Nc1nc(NCc2ccc(C(=O)Nc3ccccc3N)cc2)c2nc[nH]c2n1 +O=C(C=Cc1ccc(O)c(O)c1)NCCNc1c2c(nc3ccccc13)CCCC2 +CCOc1ccccc1N1CCN(CCCCc2cc(-c3cccs3)no2)CC1 +CC12CCC3c4ccc(O)cc4CCC3C1CC(CCCI)C2O +CCn1ncc(C(=O)N2CCC(Nc3cc(=O)[nH]c4ccc(F)cc34)CC2)c1Cl +CCCn1c(=O)c2nc(-c3cnn(Cc4cccc(Cl)c4)c3)[nH]c2n(CCC)c1=O +CCCCc1nnc(C(=O)NCc2ccccc2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +CCC(CC)(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)N1CC(F)(F)C1 +Cc1cc(C)cc(C(=O)N2CCN(C(=O)CNC3CCNCC3)C(c3ccc(Cl)c(Cl)c3)C2)c1 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+COc1ccc(S(=O)(=O)NC(C)CCN2CCN(c3cccc(C(F)(F)F)c3)CC2)cc1 +O=C(O)CCC(O)c1ccc(OCc2cccc(Br)c2)cc1 +Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4CCC([S+]([O-])C(C)(C)C)C4)cc3)nn3cccc23)n[nH]1 +COC(=O)C1CC(OC(=O)C=C(C)C)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +CC1CCCN1C(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C +O=C1CC2(C=CN1CCN1CCN(c3cc(Cl)ccc3Cl)CC1)CCCC2 +COc1cccc2c1C(=O)c1c(OC)cc(C[N+](C)(C)C)cc1C2=O +CNc1cc(N2CCC(C(=O)NCc3ccccc3C(F)(F)F)CC2)nc(C)n1 +CN(C)CCNC(=O)C(CC(=O)Nc1ccc(Br)cn1)NC(=O)c1ccc(-c2ccccc2S(N)(=O)=O)cc1 +CN(C)C(=O)c1c(CNC(=O)c2ccc3c(c2)OCCO3)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +Oc1ccc(C2Sc3cc(O)ccc3OC2c2ccc(OCCN3CCC(O)CC3)cc2)cc1 +O=C1C(c2ccccc2)=COC12CCN(CCc1ccccc1)CC2 +CCCN1CCN(Cc2ccc(S(=O)(=O)Nc3cccc(C)c3)cc2)CC1 +CCOc1nn2c(=N)n(CC(=O)c3cc(OCCO)cc(C(C)(C)C)c3)nc2c(CC)c1C +O=C(c1ccnc(F)c1)N1CC2(CCN(CC=Cc3ccc(Cl)cc3)CC2)c2cc(F)ccc21 +COc1ccc(N(C(=O)c2ccoc2C)C(C(=O)NCC(C)O)c2ccccc2F)c(OC)c1 +CN1CCN(c2ccc(-c3nc4ccc(I)cc4s3)cc2)CC1 +CCC(CO)Nc1nc(NCc2cc(Cl)ccc2O)c2ncn(C(C)C)c2n1 +COc1ccc2cc(CNCCc3ccc(Br)cc3)c(-c3ccccc3)nc2c1 +Nc1cc(C(=O)N2CCOCC2)cc(-c2cnc3[nH]cc(-c4ccncc4)c3c2)c1 +NS(=O)(=O)c1ccc(-n2cc(COC3OC(CO)C(OC4OC(CO)C(O)C(O)C4O)C(O)C3O)nn2)cc1 +CCN(CC)CC(=O)Nc1cccnc1C(=O)Nc1nccs1 +CCCCCCCN(C=O)C1CCC2C3CCC4N(C)C(=O)CCC4(C)C3CCC21C +O=C1c2ccccc2-c2nnc(-c3ccc(Cl)cc3)cc21 +Nc1cc(Cn2c(C(=O)O)c(-c3ccc[nH]c3=O)c3cc(-c4cccc(=O)[nH]4)ccc32)ccn1 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1cnc(N)nc1 +COc1cc(C2=C(c3cn(C)c4ccccc34)C(=O)NC2=O)cc(OC)c1OC +Cc1ncc(-c2cc3ncn(C)c(=O)c3c(NC(C)C)n2)s1 +O=c1c2c(oc(O)c1C(c1ccccc1)c1ccccc1)CCCCCC2 +CN(C)C(=N)c1ccccc1-c1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 +CC1CN(c2ncccc2Cl)CCN1c1nc2ccc(C(C)(C)C)cc2[nH]1 +N#Cc1cc(S(=O)(=O)Nc2nncs2)ccc1Oc1ccc(Cl)cc1-c1ccnc(N2CCOCC2)c1 +CC1CCCN1C(=O)CN1CCCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O +COc1cc(C(C)=O)ccc1OCCCN1CCC(C(c2ccccc2)c2ccccc2)CC1 +CS(=O)(=O)N1CCCC(c2csc(-c3ccccc3NC(=O)c3nc(Cl)c[nH]3)n2)C1 +CC(C)CC(NC(=O)COc1ccccc1-c1ccccc1)C(=O)NC1CC(=O)OC1O 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+CC1CCC2C(C)C(CCN3CCOCC3)OC3OC4(C)CCC1C32OO4 +O=S(=O)(NCC1CC1)c1ccc(NC2CC3CCC2C3)cc1C(F)(F)F +Nc1nc(OCc2cc(Br)cs2)c2ncn(CCOC3OC(CO)C(O)C(O)C3O)c2n1 +COc1ncc(F)cc1C1CCCN1c1ccn2ncc(C(=O)NCC(O)CO)c2n1 +CC1CNC(=O)c2cc(-c3cccc4ccc(Nc5ccccc5)nc34)[nH]c21 +CCc1ncc(Cc2cc3cc(OC)ccc3nc2O)c2cc(OC)c(OC)cc12 +COC(=O)N(NC(=O)c1c(OC)c(-c2ccccc2)nc2ccccc12)c1ccccc1F +COc1ccc(Nc2ncc(Br)cc2-c2nc(C)nc(N)n2)cn1 +O=C(Nc1ccccc1-c1ccccc1)OCCCCCCCn1cc(-c2cccnc2)nn1 +O=C(CCCCCCc1ccn(Cc2ccc(-c3ccccc3)cc2)n1)NO +COc1ccc(S(=O)(=O)Oc2ccccc2NC(=O)c2ccccc2)cc1 +CCCC(CCC)CN(NC(=O)c1ccc(CN2CCN(C)CC2)cc1)c1nc(C#N)ncc1Br +O=C(CCCCCCOc1ccccc1C(=O)Nc1ncnc2[nH]cnc12)NO +CC1SC(N)=NC2(c3ccc(F)cc3F)COC(c3cccc(C#N)c3)CC12 +CCOC(=O)c1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 +O=C1N(CCN2CCC(c3ccc(Cl)cc3)CC2)CCN1c1cccc(Cl)c1 +CC(CC(=O)O)c1cc2cc(-c3cc(OC(F)(F)F)ccc3F)ccc2o1 +CCS(=O)(=O)c1ccc(Oc2cc3cc(-c4ccc(C(F)(F)F)cn4)[nH]c3cc2C2CCC(=O)N2C)cc1 +CN(C)C(=O)c1cccnc1NCCCN1CCN(c2ccccc2OCC(C)(C)C)CC1 +CCOC(=O)N1CCN(c2cc(N3CCN(CC)CC3)c(F)cc2[N+](=O)[O-])CC1C +Cc1cccc2c1nc1n2CCC(O)=C1C(=O)Nc1ccccc1 +NC(=O)c1cccc2c1Nc1nnc(Cl)cc1C(=O)N2 +Cn1cc(-c2ccc3nc(NC(=O)c4ncccc4Cl)cn3n2)c(-c2ccc(F)cc2)n1 +CCC(C)C(NC(=O)c1ccc(C(CC)(CC)c2ccc(OCC(O)C(C)(C)C)c(C)c2)n1CC)C(=O)OC +CCOc1ccc2c(c1)c(=O)c(Cc1cccc(C(=O)O)c1)c(C(=O)O)n2Cc1cc2c(cc1CC)OCO2 +O=C(c1c(F)ccc(NS(=O)(=O)c2c(F)cccc2F)c1F)c1c[nH]c2ncc(Cl)cc12 +CCC1CN(C(=O)N2Cc3c(NC(=O)c4ccccn4)n[nH]c3C2(C)C)C(C)CN1C +CC1(C)CC(NC(=O)Nc2ccc3c(c2)NC(=O)CO3)c2ccccc2O1 +CCC(C)(C)N=c1c(O)c(O)c1=NCc1ccc(Cl)cc1Cl +CN(c1ccc([N+](=O)[O-])cc1OCC1CCCCC1)S(C)(=O)=O +COCCOCC(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +COc1ccc(Nc2ncc(C(C)(O)C(F)(F)F)cc2-c2nc(C)nc(N)n2)cn1 +N#Cc1cc(-c2ccnc(Nc3cnn(CCN4CCCC4)c3)n2)ccc1OC1CCOCC1 +CN(C)CCNc1cc(-c2ccc3ccc4ccccc4c3c2)nc2ccccc12 +CC(C)OC(=O)C(O)=CC(=O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccc(F)cc2F)c1=O +Oc1ccc(-c2cnc(N3CCc4c([nH]c5ccccc45)C3c3ccc4c(c3)CCO4)nc2)cc1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)Nc3cccnc3)cc2F)cn1 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+O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccccc3)cc2-c2ccc([N+](=O)[O-])cc2)cc1 +COC(=O)C1=Cc2c(ncnc2Nc2ccc(Oc3cccc(C(F)(F)F)c3)c(Cl)c2)NCC1 +CC(O)(C1CCN(c2nccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1)C(F)(F)F +CN(C)CCNC(=O)c1cccc2c(N)c3cccc(S(C)(=O)=O)c3nc12 +Cc1nc(CN2CCC(Oc3ncnc4c3ccn4Cc3ccccc3)CC2)cs1 +Nc1ncnc(N2CCC(c3nc(-c4ccnc(C(F)(F)F)c4)cn3CCNCCCCl)CC2)c1Br +CN(C)C12CCN(CCN3CCCC3)C(C(c3ccccc3)C1)C(c1ccccc1)C2 +O=C(C#CCCN1CCCCC1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cn1 +CCNc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +COc1ccc(C(=O)N2CCN(c3ccc(NC(=O)N4Cc5ccccc5C4)cc3)CC2)cc1 +CCN(CC)CCN(C(=O)c1cccc([N+](=O)[O-])c1)c1nc2ccc(OC)cc2s1 +CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3C#N)CC2)C(c2ccc(F)c(F)c2)NC(=O)N1C +CCCCS(=O)(=O)N(Cc1ccc(F)c(F)c1)c1cc2ccccc2s1 +Cc1cc(C(=O)NC(Cc2cccc(Cl)c2)C(=O)NCC#N)c2cc(C)ccc2c1 +CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccc(Cl)cc1n2CCOCCOCCF +CC1CN(c2ccccc2)CCN1C(=O)C1CCCCC1C(=O)NCC#N +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5Cl)CC4)cc3)cc2n(C)c1=O +CCCOC(=O)C1=CC2C(CC(OC(=O)C=Cc3cn(C)cn3)C3(C)C=CC1(OC)O3)C(C)=CCC2C(C)C +[C-]#[N+]c1ccccc1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C +CCC12CCC(=O)C=C1c1c(cc(OCC(=O)OCC(=O)O)c(Cl)c1Cl)C2 +CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(C(C)(C)CF)[nH]2)c1O +CC(C)c1cccc(C(C)C)c1NC(=O)NC1CCc2ccccc2C1 +CCc1nnc2c(NC3CCCCC3)nc3ccc(Cl)cc3n12 +CN(C)C(=O)c1c(CNC(=O)c2cnc(N3CCC(CO)CC3)s2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +FC(F)(F)c1ccc(Nc2nc(CN3CCOCC3)nc3cc(-c4ncccc4C(F)(F)F)ccc23)cn1 +CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1)B(O)O +O=C1CCC(c2cccc(C(=O)N3CCOCC3)c2)(C2CCN(Cc3ccc(Br)cc3)CC2)C(=O)N1 +CCC(CC)Oc1cccc(N(Cc2cccnc2)S(=O)(=O)CC(F)(F)F)c1 +CC(C)(CCl)Cn1c(-c2ccc(P(=O)(O)O)o2)nc2c(N)ncnc21 +N#Cc1ccc2sc(C(=O)NC3CCN(Cc4ccc(OC5CCNCC5)c(Br)c4)CC3)cc2c1 +CCCCC(C(=O)NO)C(=O)N1CCCC1c1nc2ccccc2o1 +CN1CCC23c4c5ccc(C(N)=O)c4OC2C(O)C=CC3C1C5 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +Cc1ncnc(C)c1C(=O)N1CC2CN(CCC(c3ccccc3)C3CCN(S(=O)(=O)CC(F)(F)F)CC3)CC2C1 +O=C(Nc1cccc(-c2nc3sccn3c2-c2ccnc(Nc3cccc(N4CCOCC4)c3)n2)c1Cl)c1ccccc1F +CCOC(O)=C1C(Cn2ccnc2)=NC(Cn2ccnc2)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1 +OCC1OC(n2ccc3c(-c4c[nH]cn4)ncnc32)C(O)C1O +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3CC3CCCCC3)ccc2[nH]1 +CCOC(=O)c1ncn2c1Cn1ncnc1-c1cc(NC(=O)C(C)C)ccc1-2 +Cc1cnc(Nc2cccc3[nH]ccc23)c(-c2nc(C)nc(N)n2)c1 +CCn1ncc2cc3nc(c21)CCCOCC(c1ccccc1)NC(=O)N3 +CCc1cc(C2C(c3ccc(C)cc3)CC3CCC2N3C)on1 +CCc1ccc(Oc2ccc(Cn3c(=O)oc4ccc(OCC(=O)OC)cc43)cc2)cc1 +CCC(=O)NCC(=O)N(C)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl +Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4cccs4)cc3=O)cc21 +CCn1c(CNc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCC(=O)O)c3cc(C)ccn3)ccc21 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2c(F)cccc2F)c1 +O=C(O)CCC(Cc1ccccc1)NC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)N1CCC2(CCCC2)CC1 +CNc1nc2c(N)ncnc2n1C1OC(CN(C)CCCCON)C(O)C1O +COc1ccc(NC(=O)Nc2nc3nn(Cc4cccc5ccccc45)cc3c3nc(-c4ccco4)nn23)cc1 +COc1c(C(=O)NCCN2CCCCC2)n(C)c2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21 +CS(=NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Br)cc1)c1ccccn1 +Fc1ccc(NCc2ccccc2)cc1-c1c(Cl)cnc2[nH]c(C3CCNCC3)cc12 +Fc1ccc(CNCCCCCCNCCCCCCCCNCCCCCCNCc2ccc(F)cc2)cc1 +O=c1c(C(c2cnc3ccccc3c2)c2c(O)oc3ccccc3c2=O)c(O)oc2ccccc12 +COc1ccc(CN(C)CC(O)COc2ccc(-c3ccccc3)cc2)cc1OC +CN(C)CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(NCCCN1CCCC1=O)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +COc1ccc(-c2nc(NC(=O)Cc3nn(C)c(=O)c4ccccc34)sc2C)cc1 +N#Cc1ccc(Nc2cc(Oc3c(Br)cc(Br)cc3Br)c(=O)[nH]n2)cc1 +CC(CCC(=O)O)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1 +COCCN(C)S(=O)(=O)Nc1cc(Nc2ncc(Cl)cc2-c2nc(C)nc(N)n2)cnc1Cl +Cn1c(CNc2ccc(C(=N)N)cc2)nc2cc(C(=O)N(CCCC(=O)O)c3ccccc3)ccc21 +C=CCOC(=O)N1CCCc2cc(S(=O)(=O)N3CC(c4ccccc4)NC3=O)ccc21 +COc1cc2nccc(Oc3ccc4oc(Nc5ccc(Cl)c(CN6CCN(C)CC6)c5)nc4c3)c2cc1OC +CC1CCC(C(=O)N2CCc3nc(C#Cc4ccccc4)sc3C2)CC1 +CC1(c2ccccc2)CCN(c2ccc(Cl)cc2)C(=O)O1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(-n2cccc2)cc1 +O=C(O)C1CN(Cc2ccc(-c3noc(C(F)(F)C(O)C4(c5ccc(Cl)cc5)CC4)n3)cc2)C1 +COc1cc(COc2cc3nccc(C(=O)O)c3[nH]2)ccc1Cl +COCCCCCCCC=C1CC(CO)(COC(=O)C(C)(C)C)OC1=O +O=C(Nc1ccc(Cl)c(Cl)c1)N1CCN(CC2CCCN(CC3CC3)C2)CC1 +CCCCCCCCc1ccc(OCC(=O)Cn2cc(C(C)(C)C)c3cc(C(=O)O)ccc32)cc1 +CC(C)CNC(=O)c1cnc(NCCCN)nc1NC1CCCC1 +COc1cccc(CNCC(C)Oc2cccc3ccc(N)nc23)c1 +CNc1cc(Nc2cnc(C#N)c(OC3CCNC3)n2)ncc1C(=O)OC +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4c(Cl)cccc4Cl)nc23)N1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(NCCN(C)C)nc3)NC(=O)NC1=O)C2 +O=C1c2ccccc2C(=O)N1CCCN1CCN(Cc2ccccc2)CC1 +CC(C)(C)Nc1cc(NCC2CCOCC2)c2ncc(-c3ccc(C(=O)NC4CC4)cc3)n2n1 +N#CC(C#N)=C1C(=O)N(Cc2ccc(OCCF)cc2)c2ccc(S(=O)(=O)N3CCC3COc3cccnc3)cc21 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(C(O)(O)C(F)(F)F)cc3)NC(=O)NC1=O)C2 +CCCC(=O)Nc1cc(-c2ccoc2)nc(-c2ccoc2)n1 +N=C(N)NOCCCOc1cc(Cl)cc(C(=O)N(CCc2cccnc2)CC2CC2)c1 +O=C(NS(=O)(=O)c1ccccc1)c1nc2cc(Cl)c(Cl)cc2nc1O +COC(=O)c1cccc(NC(=O)Nc2cccc(C(C)=O)c2)c1CN1CCC(Cc2ccc(F)cc2)CC1 +CN1C(=O)C(NC(=O)C(c2ccc(F)cc2)C(CO)c2ccc(F)c(F)c2)N=C(c2ccccc2)c2ccccc21 +COc1cccc(N2CCC(CNC(=O)Nc3c(C(C)C)cc(N)cc3C(C)C)(c3cccc(OC)c3)CC2)c1 +C=CC(=O)Nc1ccc(CNc2nc(Nc3cnn(CC(=O)NC)c3)ncc2Cl)cc1 +COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3)c2cc1OC +COc1ccc(OC)c(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1OC +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCCCc1ccccc1 +COCc1cc(OC)c(-c2csc3c(N(CCCF)c4cccnc4)c(OC)nn23)c(OC)c1 +COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(OCCO)cc2)ccc1O +CC(O)COc1ccc2c(c1)CCC1(CCN(C3CCC3)CC1)O2 +COC1COCCC1NC1CC2OC(C)CC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1=O)NCc1ccccc1 +COc1ccc(C(C)(O)c2nc(C)nc3ccccc23)cc1 +COc1ccc(C=C2CN(C(=O)CN)Cc3c(C(=O)NC(C)c4ccccc4)nn(-c4ccc(Cl)cc4Cl)c32)cc1 +CC(C)C1CN(C2CCNCC2)C(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1 +CCCCC(C)c1nnc(-c2nc(-c3ccc(Cl)cc3Cl)n(-c3ccc(Cl)cc3)c2C)s1 +N#Cc1cc(-c2ccnc(Nc3ccnc(N4CCOCC4)c3)n2)cnc1N1CCC(F)C1 +N#Cc1cccc(NC(=O)Nc2ccccc2C(O)CN2CCC(Cc3ccccc3)CC2)c1 +CS(=O)(=O)c1ccc(-c2nc3c(s2)CN(C(=O)CC(N)Cc2cc(F)ccc2F)CC3)cc1 +O=C(NCCc1c[nH]c2ccc3c(c12)CCNC3=O)c1cccnc1 +COc1cc(-c2cc(C)c(=O)n(C)c2)c(OC)cc1CN(C)C +CCOc1cc2ncnc(Nc3ccc(NS(=O)(=O)c4ccccc4)cc3)c2cc1NC(=O)C=CCN1CCCC1 +CCCOc1ccc2[nH]c3cnc(C(=O)OCC)c(COC)c3c2c1 +CC(=O)N1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)C(CN2CCCC2)C1 +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CC2(COC2)C1 +CC(C)(C)c1csc(C=Cc2cccc(C(CCc3ccccc3C(C)(C)O)SCC3(CC(=O)O)CC3)c2)n1 +N#Cc1ccc(Cn2c3cc(O)c(O)cc3c3ccc(O)c(O)c32)cc1 +O=C(CCCN1CCN(c2ccc(Cl)cc2)CC1)NCc1nc2ccccc2c(=O)n1-c1ccccc1 +CCN(CC)c1ncc(-c2ccccc2C)c(NC(Cc2ccc(OC(=O)N(C)C)cc2)C(=O)O)n1 +O=C1C(Cc2ccccc2)CC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +N#Cc1cc(Cl)cc(-c2cc(-c3cccnn3)ncn2)c1 +CCc1cc2c(ccc3c(CC)nn(CC(C)N)c32)o1 +COc1ccc(C=Cc2c(OC)ccc(OC)c2OC)c(OC)c1 +CCOc1ccc(C2CC2C(=O)NO)cc1-c1nc2c(CC)nn(C)c2c(=O)[nH]1 +C=CC(=O)NCC1(C)CCNc2c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn21 +COc1ncccc1-c1nccnc1OC1CC(Nc2nc3ccccc3s2)C1 +CC(C)CSc1nc2sc3c(c2c(=O)n1-c1ccccc1)CCN(Cc1ccccc1)C3 +COc1cc(C)nc(OC(C(=O)O)C(OCCc2ccc(OC)c(OC)c2)(c2ccccc2)c2ccccc2)n1 +NC(=O)N1CCOc2cc(-c3cncc(F)c3)cnc21 +Cc1ccc2cc(-c3n[nH]c4ccc(NC(=O)Nc5ccccc5)cc34)[nH]c2c1 +N#Cc1ccc(N2N=C3c4ccc(C(=O)O)cc4CCC3C2C2CCC2)cc1Cl +CN(C)C(=O)CN1CCC=C(c2[nH]c3nccc4c3c2CN(C)c2ccc(F)cc2-4)C1 +O=C(NC(CO)c1ccc(Cl)cc1)c1cc(-c2[nH]ncc2-c2cccc(Cl)c2)c[nH]1 +CCCC(=O)c1cnc2c(F)cccc2c1Nc1ccc(O)cc1C +CNc1nc2c(cc(C(=O)N(C3CC3)C3CC3)n2CCCO)c2c1ncn2C +CNCCN(C)Cc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2O)cc1 +CCc1ccc(-n2nnc(C(=O)Nc3ccccc3Cl)c2C)cc1 +CC(C)CN(CC(C)C)c1c([N+](=O)[O-])cc(S(N)(=O)=O)cc1[N+](=O)[O-] +CC1(C)OC(S)=Nc2ccc(-c3cccc(C#N)c3)cc21 +COC(=O)CCC(=O)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)CC1CCCCC1 +Cc1cc(S(=O)(=O)n2cc(-c3ccco3)[nH]c2=O)ccc1NC(=O)OC(C)C +CCC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(OC)c3)cc2c1Nc1ccc(CN(C)C)cc1 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(Cl)cc1 +COc1cc2c(N3CCN(C(S)=Nc4ccc(-c5cccc[n+]5[O-])cc4)CC3)ncnc2cc1OCCN1CCCCC1 +COc1ccc2c(c1)sc1nc(C)c(C)c(C)[n+]12 +CC(c1ccc2[nH]c(=O)sc2c1)c1ccn(-c2ccc(CCC(C)(C)O)cn2)n1 +O=C(Cc1ccccc1)Nc1ccc2c(c1)CC(=O)N(O)C2=O +O=C(NCCN1CCOC1=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)c1OC +COc1cc(C)ccc1S(=O)(=O)NC(=O)C(c1ccc2c(c1)OCO2)c1cn(C)c2cc(C#N)ccc12 +Cc1noc(C)c1-c1ccc(CNS(=O)(=O)c2c(C)noc2C)cc1 +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NO)c[nH]4)c3)cc2F)c1 +CC(C)NC(=O)Nc1c(C#N)cnn1CC(O)c1ccccc1 +COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)c(F)c1)N(c1cccc(Cl)c1F)C2=O +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CNCC(C)(C)O1 +Cn1c(=N)n(CCOc2ccc(Cl)cc2)c2cccc(Cl)c21 +COc1cc(-c2ccc3ncc(S(C)(=O)=O)c(NC4CCC(CN(C)C)CC4)c3c2)cc(Cl)c1O +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2C)c1 +CCCCOCC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(Cn2ccnc2)cc1 +NN(C(=O)c1ccc(Cl)cc1Cl)S(=O)(=O)c1ccc2c(c1)OCO2 +O=C(NCc1nc(Cc2ccccc2)co1)C(O)C(O)C(=O)N1CCCC1c1ccccc1 +CC1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1c[nH]c2c(-c3ncon3)ccc(F)c12 +O=C(C1Cc2ccccc2CN1C(=O)CCCc1ccccc1)N1CCCC1 +CC(C)n1c(=O)n(C(=O)NC2CCNCC2)c2ccccc21 +CC(c1ccc(F)cc1)N(Cc1cccc(C(=O)O)c1)C(=O)c1cn2ccccc2n1 +Nc1nc(N)c2nc(CN3c4ccccc4C=Cc4cc(OCCC(=O)O)ccc43)cnc2n1 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+O=C(O)c1cc(-c2cccc(COc3ccc4c(=O)n(C5CC5)sc4c3)c2)ccc1Cl +COc1cc(C#N)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC(NCc1ccoc1)c1ccccc1 +COC(=O)N1CCc2c(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)n[nH]c2C1 +CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)cc2OC2COC2)c1 +CC(Nc1cc(-c2[nH]c(SCc3ccccc3)nc2-c2ccc(F)cc2)ccn1)c1ccccc1 +CC(=NNC(=O)Cn1c(=O)c(Cc2ccccc2)nc2ccccc21)c1ccc(O)cc1 +COC1(c2cc(F)cc(OCc3ccc4c(c3)sc(=O)n4C)c2)CCOCC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(C(F)(F)F)ccc3F)C2)cc1 +CC(O)(c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1)c1nccs1 +O=C(NCCCCCCS)c1cc(-c2ccc(F)cc2)nn1CCCO +CCCCC(NC(=O)OCC1(CC)CCCCC1)C(=O)C(=O)NC(C)c1ccccc1 +COCC1CC(O)CN1Cc1cn(-c2ccnc(Nc3ccc4c(c3)c(Cl)c(C)n4C)n2)nc1C +CCN1C(=O)c2c(nc(C#N)n2Cc2ccc(OC)cc2)N2C1=NC1CCCC12 +CC(C)NCCCCN(CC1Cc2ccccc2CN1)C1CCCc2cccnc21 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cccc(-n2cccn2)c1 +CCCCCCCCCCCCCCCCCCOC(=O)N1CCN(C(=O)c2ccc(Cc3noc(=O)[nH]3)cc2)CC1 +CN1CCc2c(sc3c2c(=O)n(-c2ccccc2)c2nnc(SCc4ccccc4)n32)C1 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+Cn1ccc2c(N3CCN(CCCCN4C(=O)SC5(CCCC5)C4=O)CC3)nccc21 +CN(C)CCNCCC(=O)Nc1csc2c1C(=O)c1ccccc1C2=O +CCCC(=O)c1cccc(NC2=NC(N)=NC3(CCCCC3)N2)c1 +Cc1ccc(NC(=O)c2cc(C(C)C)ccc2O)cc1-n1ccn2nc(-c3cccnc3)cc12 +N#CC1=C(c2ccc(C#N)cc2)CC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)NC1=O +CC(C)C(N)=NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +CCc1nn(-c2ccc(F)cc2)c2c1CCN(c1cccc(OC)c1)C2=O +CCNC(=O)Nc1cc2c(-c3ccncc3)ccc(CNC(=O)OCCN3CCOCC3)c2cn1 +CCCOC1CNC(C(O)C(Cc2cc(F)cc(F)c2)NC(=O)C(CCc2ccccc2)N2CCC(CC(C)C)C2=O)C1 +O=C(CCCCCCCNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1)NO +Cc1cc(C(=O)Nc2cccc3ccccc23)nn1-c1cccc(C(F)(F)F)c1 +CCCN1C(=O)C(NC(=O)Nc2cccc(C(F)(F)F)c2)N=C(N2CCN(C)CC2)c2ccccc21 +Cc1ccc(Cl)c2nc3cccc(C(=O)NCCCN(C)CCCNC(=O)c4cccc5nc6c(Cl)ccc(C)c6nc45)c3nc12 +NS(=O)(=O)c1ccc(Oc2cn(-c3nc(C(=O)O)cs3)nc2-c2ccccc2)cc1 +Nc1nccc(-c2cc3c([nH]2)C(CCF)CNC3=O)n1 +O=C(c1cc(F)ccc1-n1nccn1)N1CCC2CN(c3cc(C(F)(F)F)ccn3)C2C1 +Cc1cc(C)cc(-c2[nH]c3ccc(C(=O)N4C5CCC4CC5)cc3c2CCNCCCCc2ccncc2)c1 +O=C(C=Cc1ccc(Br)cc1)Nc1cc(-c2ccc(Br)cc2)[nH]n1 +Cc1sccc1C(=O)NC1C(CC=CCCCC(=O)O)CC2CC1C2(C)C +COC(=O)c1nn(C(=O)c2cccc(OC)c2)c2ccc([N+](=O)[O-])cc12 +CNCC(CC1CCCCC1)NC(=O)N1CCCC(C(O)(CCCNC(=O)C2CC2)c2cccc(Cl)c2)C1 +CC(=O)N1CCC(n2cc(-c3ccn4c(-c5cccc(NC(=O)NCC(F)(F)F)c5)cnc4c3)cn2)CC1 +O=C(O)CCc1csc(NC(=O)c2cc3c(n(CC4CCCCC4)c2=O)CCCCCC3)n1 +Nc1cc(Cn2c(C3=NS(=O)(=O)c4ccccc4N3)c(-c3ccc[nH]c3=O)c3cc(Cl)ccc32)ccn1 +NCCn1nc2c3ccccc3sc3c(NCCNCCO)ccc1c32 +O=C(CSC(c1ccc(Br)cc1)c1ccc(Br)cc1)NCCCc1ccccc1 +CN1CC=C(c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)CC1 +COc1ccccc1CCN1Cc2cccc(C(=O)Nc3cccc(-c4nc5ccccc5[nH]4)c3)c2C1=O +CC(C)C(NC(=O)C(CO)NC(=O)NCCCCNC(=N)N)C(=O)NC1CCCN(C(=N)N)C1O +O=C(Nc1ccc2c(c1)C(=O)N(CCC1CCN(Cc3ccccc3)CC1)C2=O)c1ccccc1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(N3CCC(CO)CC3)cc(-c3ccccc3)n2)CC1 +CCCC(Oc1cc(C)c(-n2cc(C3CC3)cn2)c(C)c1)c1ccc(C(=O)NCCC(=O)O)cc1 +NC(=O)c1ccc(-n2c3c(c4ccccc42)C(=O)CCC3)cc1NCC1CC1 +COc1cc(Cl)cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncc(F)cn5)ccc43)cc2F)c1 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+Cn1c(=O)[nH]c2nccc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c4ccccc34)c21 +CNS(=O)(=O)N1CC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +O=C1C(Cl)=C(Cl)C(=O)N1c1ccc(Cl)c(Cl)c1 +NS(=O)(=O)c1ccc(NC(S)=NC(Cc2c[nH]cn2)C(=O)O)cc1 +O=C(O)C(CSCCO)=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 +Cc1cccc2c(=O)[nH]c(-c3ccc(CN)cc3)nc12 +O=C(O)Cc1ccc(CNc2cccc(-c3c(C(O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)cc1 +Fc1ccc(F)c(CNc2ncnc3c2cnn3CC(Cl)c2ccc(Br)cc2)c1 +NC(=O)c1ccc2c(ccn2CC(=O)COc2cccc(-c3ccccc3)c2)c1 +O=C(O)c1cccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)c1OC(F)F +Fc1ccc(CNc2nc(Nc3ccccc3)nc(Nc3ccccc3)n2)cc1 +O=C(NC1CN(Cc2c(F)cccc2F)CC(F)(F)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCN1CCC(c2ccccc2)CC1)c1cscn1 +CCOCCn1cc(C2CCN(Cc3cccc(OCC(=O)O)c3)CC2)c2ccccc21 +O=C1CCCC2=C1C(c1ncccc1Br)N=C(Nc1nc3ccccc3o1)N2 +Cc1cc(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C(C)C)n2)c(OCC2CC2)cc1C1CCNCC1 +CN1C(=O)C=CC2(C)C3CCC4(C)C(O)C(=Cc5cncnc5)CC4C3CCC12 +Cc1c(C(=O)NC2CCCC2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(C)ccc1C +O=C(O)C(CCCCCCCc1ccc2c(n1)NCCC2)NS(=O)(=O)c1ccccc1 +CCn1cc(C(=O)c2cc(OC)c(OC)c(OC)c2)c2ccc(OC)cc21 +CC1=CC(=O)N(Nc2nc(-c3cccs3)nc3sc(-c4cccc(O)c4)c(C)c23)C1=O +CC(C)CN(CC(C)C)c1ccc(C(CC(=O)O)C(F)(F)F)cc1NC(=O)Nc1ccc(F)cc1F +Cc1nccc2cc(NC(=O)NCC(=O)N3CCCC3)ccc12 +CCCn1c(=O)ccc2c(-c3cnc(-c4ccc(CO)nc4)s3)n[nH]c21 +O=C(O)C(Cc1ccccc1)N(Cc1cccc([N+](=O)[O-])c1)C(=O)c1ccc(Cl)cc1Cl +COc1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CC1CCCN1CCN1CCc2cc(-c3ccc(F)cc3)ccc2C1=O +CCC(C#Cc1cc(-c2ccc(C)cc2)n(-c2ccc(OC)cc2)n1)N(O)C(C)=O +O=C(Oc1ccccc1)c1cc2cc(CCl)ccc2oc1=O +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCCCN(C)CCCNc4c5c(nc6ccccc46)CCCC5)c3C(C1)C2 +Cc1cc(OCC(O)CN2CCN(c3ccc(Cc4ccc(F)cc4)cc3)CC2)c(C)c(C)c1N +O=C(NCCO)c1cccc(-c2cccc3cn(Cc4cccc(C(F)(F)F)c4)nc23)c1 +O=C(C=Cc1cccc2cc[nH]c12)CC(=O)C=Cc1cccc2cc[nH]c12 +COc1ccc(-c2ocnc2C(=O)Nc2cnn(CCn3ccc4cc(OC)c(OC)cc43)c2)cc1 +CCCn1c(=O)c2nc(C3CCCC3)[nH]c2n(CCCOC(=O)c2cccc(S(=O)(=O)F)c2)c1=O +CCOC(=O)C1=C(C)NC(=Cc2cc(C)n(-c3ccc(CN(C)C)cc3)c2C)C1=O +O=C(Nc1nc2c(Cl)cccc2s1)NC1CCCCC1CN1CCCC(Cc2ccc(F)cc2)C1 +CC(C)c1nc2c(Cl)cccn2c1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1 +COc1cccc(-c2ccc3cccc(C(=O)NCCN(C)C)c3n2)c1 +CCc1c(Sc2ccccc2)n(OC(C)C)c(=S)[nH]c1=O +O=P(O)(O)OC1C(CO)OC(OC2C(CO)OC(OCCCc3ccccc3)C2OP(=O)(O)O)C(O)C1OP(=O)(O)O +CCNC(=O)NCCC(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1 +Cc1cc(C(=O)Nc2cc(Cl)cc(N3CCCCC3)c2)cc(C)c1OCCN +Nc1ncc(-c2cc(N3CC4CC(C3)N4C3COC3)nc(C3CC3)n2)cc1OC(F)F +CONC(=O)c1ccc(C)c(Nc2ncnn3cc(C(=O)OC)cc23)c1 +Cc1cc(F)ccc1CNc1ccc(-c2nc3c(cc2Cl)OCCO3)cn1 +Cc1cc(CN(C)C)ccc1C(=O)Cn1ncc(OCc2ccc(Br)cn2)cc1=O +COc1ccc(Cn2c(CCC3C=Nc4ccccc43)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)CN)cc1 +COCCNC(=O)c1ccc(Nc2cc3cc(-c4cnn(CC(C)(C)O)c4)ccc3cn2)c(OC)c1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c(C2CC2)c1C +CC[N+](C)(CC)CCOC(=O)C(O)(c1ccccc1)c1ccccc1 +Cc1cn(C2C=CC(COP3(=O)OCc4cc5ccccc5cc4O3)O2)c(=O)[nH]c1=O +CCN1c2ncccc2C(=O)Nc2c(C)cc(NCCO)nc21 +Cn1ncnc1COc1cccc(-c2cnnc(-c3ccccc3)c2)c1 +COc1ccccc1CNCCn1c(=O)c2ccc3c(=O)n(CCNCc4ccccc4OC)c(=O)c4ccc(c1=O)c2c34 +CC(C)(O)c1cncc(-n2nc(C(F)(F)F)c3ccccc32)c1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc4cc(OCC(=O)O)ccc4n3)C12 +CCCN(CCCNc1ccnc2cc(Cl)ccc12)Cc1ccco1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1ccc(F)cc1F +Cc1ccccc1C(=O)NCCNC(=O)c1ccc(-c2cccc3[nH]nc(N)c23)cc1 +C#CC(C)n1[nH]c(=O)c2[nH]c3cc(Cl)ccc3c(=O)c2c1=O +N#CCNC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +N#Cc1c2n(c3c(N4CCN(CCc5ccccc5Cl)CC4)ncnc13)CCCC2 +COC(=O)c1csc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3ccccc3[nH]2)o1 +CC#CCn1c(N2CCCC(N)C2)nc2c1C(=O)N(Cc1nc(C)c3ccccc3n1)C1=NCCCN12 +Cc1ccn2c(=O)n(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)nc2c1 +Cc1nn(Cc2ccc(NC(=O)c3cc4cc(Cl)ccc4o3)cc2)c(C)c1CC(=O)O +OC1CCC(Nc2ncc(Cl)c(NC34CC5CC(CC(O)(C5)C3)C4)n2)CC1 +Nc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 +CC(=O)N1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cc(-n2nccn2)ccc1F +CCc1cc(NC(=O)NC(C)C(O)CN2CCCC(Cc3ccc(F)cc3)C2)cc(-c2nnnn2C)c1 +COc1ccc(-c2nsc(C)c2C(=O)N=C(N)NCc2cc(Cl)c(NC(=O)CN3CCC3)c(Cl)c2)cc1 +O=C(c1ccc(F)cc1)C1CCN(CC(=O)N(Cc2ccccc2)Cc2nc3c(c(=O)[nH]2)COCC3)CC1 +CN1c2ccc(-c3cncc(Cl)c3N3CCC4(CCCN4CCCS(C)(=O)=O)CC3)cc2CS1(=O)=O +O=C(NC1CC(O)C1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +O=C(Nc1ccc(B(O)O)cc1)c1ccc(C=C2SC(=O)N(Cc3ccc(F)cc3)C2=O)cc1 +O=C(NCc1cc(Cl)cc(Cl)c1)C1CCCC1C(O)CCc1cccc(OC(F)(F)F)c1 +O=C(NC1CCOCC1O)c1cn(Cc2ccc(-n3cccn3)cc2)c2cccnc12 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)cc1-c1ccc(F)cc1 +COC(=O)N1CCC(Sc2cccc(C(CC#N)Nc3nc4nc(C)ccc4[nH]3)c2)CC1 +CCOC(=O)C1(Cc2ccccc2)CCc2cnc3c(-c4ccc(Cl)cc4)cnn3c21 +O=C(O)C12CC3CC(C1)C(NC(=O)C1(N4CCN(c5ccc(C(F)(F)F)cn5)CC4)CCC1)C(C3)C2 +CN1CCC(O)(C#Cc2ccc3c(c2)-n2nc(C(N)=O)cc2C2(COC2)CO3)C1=O +N#Cc1cc(C(=O)NC(CO)c2ccccc2)ccc1-c1cn[nH]c1 +O=c1cc(-c2ccc(F)c(F)c2)oc2c1ccc1ccccc12 +O=S(=O)(NCCN1CCc2ccccc2C1)c1ccc2ccccc2c1 +COc1nc(N2CC(OC)C2)nc(OC)c1NC(=O)CC(C)(C)C +COC(=O)C1C2CC3CCC1N3CC2=Cc1ccc(I)s1 +CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccccc4)c3)cc21 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+CCCC1(O)CCC2(C)C(CCC3C4CCC(=O)C4(C)CCC32)C1 +COc1ccc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c2cc(C(F)(F)F)nn12 +CC1CN(CCC(=O)N(c2ccccc2)C(Cc2ccccc2)C(=O)O)CCC1(C)c1cccc(O)c1 +O=C(Nc1cc2cc[nH]c(=O)c2cc1Cl)C1CNCCC1c1ccccc1 +O=c1c(=Cc2ccco2)sc2nc3cc(Br)cnc3n12 +CCC(CC(C)C)NC(=O)C1CNCC(N2CC(=O)N(c3ccccc3Cl)CC2(C)C)C1 +CC(C)CN(Cc1ccc(NC2CCN(S(C)(=O)=O)CC2)cc1)S(=O)(=O)Cc1ccccc1 +Nc1ncc(C2CCOCC2)cc1-c1ccc(C(=O)NC(CO)c2ccccc2)cc1Cl +O=C(Nc1cccc2c1OC(c1nnn[nH]1)CO2)c1ccc(OCCCCc2ccccc2)cc1 +COc1cccc(CNC(=O)n2sc3ncccc3c2=O)c1 +O=[N+]([O-])c1cn2c(n1)OC(COc1ccc(-c3ccc(F)cc3)nn1)CC2 +Cc1c(C(O)CN2CCC3(CC2)CCN(C2=C(C4CC4)C(=O)OC2)C3=O)ccc2c1COC2=O +CC12CCC3C(C(Cc4ccc(N)cc4)=CC4=CC(=O)CCC43C)C1CCC2=O +c1ccc(Cn2c(SCc3ccncc3)nnc2-c2cccs2)cc1 +COc1ccc(C(=O)C=Cc2ccc(OC)c(OP(=O)(O)O)c2)cc1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)cc1C(=O)NCc1ccncn1 +O=C(OCCOc1cccnc1)C1CCCCN1S(=O)(=O)Cc1ccccc1 +c1ccc(-c2noc(COc3ccc(C4CCNCC4OCc4ccc5ccccc5c4)cc3)n2)cc1 +N#Cc1ccc(-c2cnc(N)c(-c3ccc(C(N)=O)cc3)n2)cc1 +O=C(c1ccc(F)cc1)N1CCN2C(=O)c3ccccc3C12c1ccc(Cl)cc1 +Cc1cc(OCc2cccc(-c3c(C)cccc3C)c2)ccc1CCC(=O)O +CN1OC2(N=C1N)c1cc(-c3cc(Cl)cc(C#N)c3)ccc1CC21CCc2ccccc2CC1 +CC1Cc2ccccc2N1C(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1 +NC(=O)c1cccc2[nH]c(-c3ccc(C4CCCN4)cc3F)nc12 +CC(=O)N(C)c1ccc2ccn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 +CN1CC=C(c2cc(C(F)(F)F)ccc2N2CCOc3cc(S(=O)(=O)Nc4ncns4)ccc32)CC1 +COCCOCCOCCOCCOC(=O)OC[n+]1ccc(NC(=NCCCCCCOc2ccc(Cl)cc2)NC#N)cc1 +Cc1ccc(NC(=O)NS(=O)(=O)c2ccc(OCCCN3CCCCC3)cc2)cc1 +COc1ccc2[nH]c3c([N+](=O)[O-])cc4cn[nH]c4c3c2c1 +COc1ccc(CN2CCN(CCCC(=O)NC3c4ccccc4SCC4CCCCC43)CC2)cc1 +Cc1ccc2c(N3CCN(CCc4ccc5c(c4)OCC(=O)N5)CC3)cccc2n1 +CN(C1CCN2CCc3ccccc3C2C1)S(=O)(=O)CC(C)(C)C +c1ccc(-c2csc(Nc3nc(N4CCOCC4)nc(N4CCOCC4)n3)n2)cc1 +N#Cc1ncc2nc1OCCCCCOc1cc(NCc3ccncc3)c(Cl)cc1NC(=O)N2 +CC(=O)N1CCN(c2cnc3cccc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +c1ccc(CNCC2CCN(CCc3c[nH]c4ccc(-n5cnnc5)cc34)C2)cc1 +O=C(c1cccnc1)N1CC2C(CNc3nc(-c4ccccn4)cs3)C2C1 +COc1cccc(C(C)Nc2cc(-c3cccc(C)c3)nc(C)n2)c1 +CCCCCc1cc(O)c2c(c1)OC(C)(C)C1CC(O)C(C)=CC21 +O=C(Nc1nnc(-c2ccc(Cl)cc2)s1)c1ccccc1F +COCCc1sc(S(=O)(=O)NC(=O)Nc2ncc(SC)s2)cc1C +Cc1nccc2c1[nH]c1cc(OCc3ccccc3)ccc12 +CNC(C)C(=O)NC(C(=O)NC(CCCNC(=O)OCc1ccccc1)C(=O)NC1CCCc2ccccc21)C(C)C +O=C(CCc1ccccc1)c1ccc2nc3c(cc2c1)CCCO3 +COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)C3CCOCC3)CC1)C(=O)C2 +Cn1cc(-c2cnc3nc(OCc4ccc(Oc5ccc(Cl)c(C(F)(F)F)c5)cc4)ccn23)cn1 +Cn1cc(-c2cn(-c3ccnc4c3c(C(F)(F)F)nn4-c3ccc(C(N)=O)cc3Br)cn2)cn1 +NC(CC1CCCCC1)P(=O)(O)CC(=Cc1ccc(Br)cc1)C(=O)O +O=C(C=CCN1CCCOCC1)N1CCc2c(sc3ncnc(Nc4ccc(F)c(Cl)c4)c23)C1 +CCCCNC(=O)C1CCN(C(=O)CCC(=O)N(CC(C)(C)C)c2ccc(Cl)cc2C(O)c2ccccc2Cl)CC1 +O=C(Cc1c(-c2ccccc2)[nH]c2ccccc12)N1CCCC1 +Cn1cc2c(OCC(=O)NCC(O)CN3CCc4ccccc4C3)cccc2n1 +O=C(NO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1ccc(Cl)cc1 +CCCCCCCCCCCCCCCCNCCOc1ccc(C(=O)c2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cc1 +NC1CCC(Nc2nc(NCc3ccc(-c4cccs4)nc3)c3ncn(C4CCCC4)c3n2)CC1 +CN(C1(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)CC1)S(=O)(=O)c1ccccc1F +COC1CCN(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C(C)C1 +CC(C)=CCOc1cc(Oc2ccc(S(=O)(=O)N3CCOCC3)cc2)cc(C(=O)Nc2cc(C)n(C)n2)c1 +CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(COc3ccccn3)n1CCO2 +COc1ccc2c(c1)c(C(C)C(C)C(=O)O)c(C)n2Cc1ccc(Br)cc1 +C[N+](C)(CC#CCN1CCCC1=O)CCCCCC[N+](C)(C)CCCN1C(=O)c2ccccc2C1=O +CC(=O)N1N=C(c2cc(F)ccc2F)CC1(CC(F)CN)c1ccccc1 +CN1CCN(CCCCN(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)C2CCC3(c4ccc(C#N)cc4)CC23)CC1 +CCC12CCC3C4CCC(=O)C=C4C(CO)CC3C1CCC21C=CCO1 +O=C(Nc1ccc(Nc2ncnc3cc(OCCCN4CCOCC4)ccc23)cc1)NC1CCCCC1 +Cc1cccc(C)c1N1CC(CC(C)C)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1=O +COc1cccc(CCCOC(=O)C2CCCCN2C(=O)NCC(C)(C)C)c1 +O=C(Nc1ccc(Cl)cc1)c1cccc2cc(Oc3ccncn3)ccc12 +CC(C)(CO)CNC(=O)c1cc2cc(C#N)ccc2n1Cc1cccc(OC(F)(F)F)c1 +Cc1ccc(C(=O)Nc2ccc(N3CCOCC3)c(C(F)(F)F)c2)cc1NC(=O)C=Cc1cccnc1 +CCCCCCCCCCCC(CC1OC(=O)C1CCCCCC)OC(=O)CCNC=O +CNC(=O)CCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(O)c1 +c1ccc(C2(c3nnc4n3CCCCCC4)CCCCC2)cc1 +CC(C)(C)NC(=O)C1CCC2C3CCc4cc(C(=O)O)ccc4C3CCC12C +Cc1nc(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)c2ccccc2n1 +Cc1nn(C)c(C)c1N(C(F)F)S(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1 +O=C1NC2CSC(CCCCCc3cn(Cc4ccc(C(=O)O)cc4)nn3)C2N1 +O=C1CN=C(n2cnc(C3CC3)n2)C=C2c3cccc(C4CC4)c3CCN12 +CCOc1ccc(-c2nc(-c3ccc(C(=O)O)o3)cs2)cc1OCC +COc1ccc(C2CC(c3ccc4ccccc4c3OC(C)=O)=NN2C(C)=O)cc1 +N=C(N)c1ccc2ccc(CN(CCc3c[nH]cn3)C(=O)c3cccc4ccccc34)cc2c1 +CC1CC(c2cc3c(F)cccc3s2)CCN1CC(O)COc1cccc2[nH]ccc12 +COc1cc2cc(C(=O)C3CCC[N+](C)(Cc4ccccc4)CC3)sc2cc1OC +CCCCCCCCCCCCCCCNOC(=O)CC1CCC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1 +COc1ccccc1C1=C(c2ccccc2)C(=O)NC1=Cc1ccc(C=CC(=O)O)o1 +Cc1nc(C#Cc2cncc(N(C)c3cccnc3)c2)cs1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(C(CC(=O)O)c2ccccc2Cl)cc1 +COCCS(=O)(=O)NC(=O)c1cnc(OCC23CC4CC(CC(C4)C2)C3)c(C2CC2)c1 +CN1C(=O)C2(N=C1N)c1cc(-c3cccnc3)ccc1CC21CCc2ccccc2CC1 +O=C(Cn1nc(C2CCCCC2)c2ccccc2c1=O)NC1Cc2ccccc2C1 +Cc1nc(N2CCCCC2)c2[nH]c(-c3ccccc3)nc2n1 +O=C(Nc1nc(Cc2cc(F)cc(F)c2)no1)c1ccc(OC2CCC(C(=O)O)CC2)cc1 +COc1ccc2c(c1)CCC(NCC1CCC(CNS(=O)(=O)c3ccccc3)CC1)C2Cc1cccnc1 +CC(C)(CO)CNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +COc1ccc(C(=O)NC(=O)Nc2ccc3c(c2)NC(=O)C3=Cc2[nH]c(C)c(CCC(=O)O)c2C)cc1 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)N4CCC(O)CC4)nc3)cc12 +O=C(O)CC(NC(=O)OCc1ccccc1)C(=O)COC(=O)Cc1coc2ccccc12 +Nc1nn2cccnc2c1C(=O)Nc1cn(CC(=O)N2CCN(CC3CC3)CC2)nc1-c1cc(Cl)ccc1OC(F)F +Cc1[nH]c(-c2cc(S(C)(=O)=O)ccc2Oc2ccc(F)cc2F)c2c1C(=O)NCC2 +Cn1c(NCC(=O)c2ccccc2F)nc(-c2ccncc2)cc1=O +Nc1nc2c(cnn2CCN2CCc3ccc(Cl)cc3CC2)c2nc(-c3ccco3)nn12 +Cc1cccc(-c2noc(C3CCCCN3C(=O)c3cccs3)n2)c1 +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +CCOC(Cc1ccc(OCC=C(C)c2ccc(-c3ccccc3)cc2)cc1)C(=O)O +CC(NC(=O)Nc1cc2[nH]nc(CC#N)c2cn1)c1ccccc1 +Cc1nc(CCCCCCC(=O)c2ccccc2)n2nc(N3CCCC3)ccc12 +CCN(c1cc(C(C)C)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +CCOC(=O)OC1=C(C)C2(OCCO2)C(=O)C2=C1N1CC3NC3C1(OC)C2COC(N)=O +CC(C)C(S)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)O +O=C(OCc1cccs1)c1cnn2c1n[n+]([O-])c1ccc(C(F)(F)F)cc12 +COc1ccc2c(Nc3ccc(Cl)cc3Cl)c(C#N)cnc2c1 +O=C(Cc1ccccc1)Nc1ccsc1-c1nc(O)c(O)c(C(=O)O)n1 +CCON=C1c2c(cc(F)c(-c3cccc4c(C)c[nH]c34)c2F)NC(C)(C)C1O +NCC(=O)Nc1ccc(S(=O)(=O)Nc2nnc(S(N)(=O)=O)s2)cc1 +Cc1cc(-c2ccc(C(N)=O)c(NC(C)(C)C)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c2n1 +CC(C)S(=O)(=O)NCC1CCC(NC(=O)Cn2ccc3cc(Cl)ccc32)CC1 +COc1ccc(CCNC(=O)CC(C)(C)NCC(=O)N2CCCC2C#N)cc1OC +COCc1cc(C(=O)Nc2cncc(C(=O)c3cn(C(C)C)c4ncncc34)c2)nn1C +O=C(O)C1CCCN1C(=O)c1cccc(COc2ccc(-c3cc(F)c(F)c4cc(CO)sc34)cc2)c1 +CCC1OCC(=O)C1NC(=O)C(CC1(C)CCCC1)NC(=O)c1ccc(NS(=O)(=O)c2cccc(OC)c2)cc1 +O=C(Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cccc(Cl)c3F)ccc2[nH]1)C1CC1 +COc1ccc(CCN2C(=O)C(O)=C(C(=O)c3ccccn3)C2c2cccc(Cl)c2)cc1 +COC(=O)c1cccc2c1c(C(=O)c1ccc(Cn3c(C)nc4cnccc43)cc1)cn2CC(=O)N(C)C +CCCN(CCC)S(=O)(=O)c1cc(Br)cc2c1N(C(C)=O)CC2 +CSCCC(NC(=O)NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)C(=O)O +COCCNc1n[nH]c2cc(NC(=O)NC(COC)c3ccc(F)cc3)ncc12 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+O=C(c1ccn(-c2cc(F)c(O)c(F)c2)c1)c1ccc(Br)cc1F +COCCOCC(=O)N1CCC(c2nc(-c3ccc([S+](C)[O-])cc3)c(Sc3ccc(Cl)cn3)o2)CC1 +CC(C)n1c(=O)c(C(=O)NC2CC3CCC(C2)N3CCS(=O)(=O)O)cc2ccccc21 +O=c1[nH]nc2[nH]c(CNCc3ccc(Cl)c(Cl)c3)nc3cccc1c32 +[H]C([H])(c1ccccc1)N1CC(C)N(C(=O)NCc2ccccc2)C(C)c2ccncc21 +Oc1nc2ccccc2n1C1CCN(Cc2ccc(-c3nc4ccccc4cc3-c3ccccc3)cc2)CC1 +COc1cnc(C(N)=O)nc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(C)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 +Cc1cn(Cc2ccc(Cl)cc2Cl)c2c(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 +CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1CSC(=S)N(CC)CC +O=S(=O)(CCCF)NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2 +CNCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(OC)cc2)c1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(C=O)C(C)C +CCOC(Cc1cccc(C2=NOC(c3ccccc3)C2)c1)C(=O)O +Cn1cc(S(=O)(=O)NC2CCN(CCOc3ccccc3-c3ccccc3)CC2)cn1 +COCOc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2noc(C)n2)cc1 +CN(C(=O)C(Cc1ccc2ccccc2c1)N(C)C(=O)c1cccc(CN)c1)C(CO)Cc1ccccc1 +CCCCCCCc1cc(=O)c2cc([N+](=O)[O-])ccc2[nH]1 +COC(=O)C1C(OC(=O)c2ccccc2)CC2CCC1N2CCO +O=C(c1ccc(-c2ccccc2C(F)(F)F)nc1)N(Cc1ccccc1)CC1CCCO1 +CC1(C)CC1C(=O)NC(=CCCCCCNC(C)(C)P(=O)(O)O)C(=O)O +CS(=O)(=O)N1CCC(n2cnc3cnc4[nH]ccc4c32)CC1 +CC1CN(c2sc(C3CC3)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21 +NCCn1cc(NC(=O)c2c(N)nn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1 +Cn1cnc(S(=O)(=O)N(CCN(Cc2cncn2C)c2ccc(C#N)cc2)Cc2cccc(C#N)c2)c1 +O=S(=O)(NCc1ccc(F)cc1)c1ccc2c(c1)nc(SCCNCc1ccccc1)n2Cc1ccccc1 +CCOC(=O)c1sc(N2C(=O)C(O)=C(C(=O)c3ccco3)C2c2cccc(Cl)c2)nc1C +Clc1ccc(-c2n[nH]cc2-c2ccnc(NC3CC3)n2)cc1 +CNNC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1C +CC(C)n1nc(-c2ccc(O)cc2)c2c(N)ncnc21 +Fc1cccc(-c2cc(N(CCCN3CCCCCC3)Cc3ccc4c(c3)OCO4)on2)c1 +Cc1nc(NCc2nccs2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CCC(=O)NC1CCc2c(-c3ccc(C(F)(F)F)c(F)c3)cncc21 +COc1ccccc1C(=O)NCCSC1c2ccccc2COc2ccc(C(=O)O)cc21 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCN(Cc2cccc3cc[nH]c23)C1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(N3CCCCC3=O)c2)CCCCC1 +O=C(Nc1ccc(N2CCN(C(=O)c3cccc(F)c3)CC2)cc1)N1Cc2ccccc2C1 +Fc1cc(Cl)ccc1C(NC1CCN(c2ccc(Cl)cc2)CC1)c1cccnc1 +Cc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cnccc2[nH]1)C1CC1 +CC1CCCC(n2c(=O)[nH]c3cnc4[nH]ccc4c32)C1 +CC(C)n1cnc2cnc(NC(=O)N3CCCc4cc(CN5CCCC5=O)c(C=O)nc43)cc21 +CC(=O)c1c(N(CCCF)S(=O)(=O)c2ccccc2)sc2ccccc12 +CC(C)(N)C(NC1COCc2cc(C#Cc3ccc(CN4CCOCC4)cc3)ccc21)C(=O)NO +NCC(NC(=O)c1ccc(-c2cn[nH]c2)c(OCCO)c1)c1ccccc1 +CC(C)CS(=O)(=O)N1CCCC2CN3CCc4cc5c(cc4C3CC21)OCO5 +COc1ccc(CCOc2cc(C3=NN(C4CCCCCC4)C(=O)C3(C)C)ccc2OC)cc1 +COc1nc(-c2nc3n(n2)CCCC3c2cc(-c3ccc(C(F)(F)F)cn3)ccc2Cl)ccc1-n1cnc(C)c1 +O=CC(CC1CCNC1=O)NC(=O)C(CC1CCCCC1)NC(=O)OCCc1cccc(Cl)c1 +C[n+]1c2ccccc2cc2[n-]c3c([N+](=O)[O-])cc([N+](=O)[O-])cc3c21 +O=C1c2cccnc2C(=O)c2c1c(C(=O)OCCCN1CCCCC1)c1ccccn21 +CC(c1ccccc1)N1C(=O)c2ccc(C(=O)Nc3cc(Cl)ccc3C(=O)O)cc2C1=O +COC(=O)CSc1nnc(Cc2csc(NCCC(=O)O)n2)n1NC(C)=O +O=C(NC(Cc1ccccc1)CN(Cc1ccccc1)CC(Cc1ccccc1)NC(=O)OCc1nccs1)OCc1cncs1 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+CCOC(=O)Cc1cc(-c2ccc(F)cc2)n(-c2ccc(S(C)(=O)=O)cc2)c1C +COC(=O)C(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 +[C-]#[N+]c1ccc(CCN2CCN(C(=O)Cc3ccc(-n4cnnn4)cc3)CC2)cc1F +COc1ccc(C(O)(c2ccc3nc(OC)c(Cc4ccc(-n5cccn5)cc4)c(Cl)c3c2)c2cncs2)cn1 +NS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccn(C(F)F)c(=O)c2)cc1 +O=S(=O)(NCCc1c[nH]cn1)c1ccc2ccccc2c1 +COc1ccc(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)C(CSc2ccc(C)cc2)C(=O)NO)cc1 +CNC(=O)C(c1ccccc1)N1CCn2c(C3CC3)nc(Cl)c2C1CCc1ccc(C(F)(F)F)cc1 +C=CCNc1ccc2c(c1)C(=O)c1ccc(C3=NCCN3)cc1S2(=O)=O +Cc1ccc(-c2cc3c(N)ncnc3nc2-c2ccc(C=Cc3ccccn3)cc2)cc1 +c1coc(CNc2ncccc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c1 +O=C1NCCN1CCN1CCC(n2cc(-c3ccc(F)cc3)c3cc(F)ccc32)CC1 +O=C(c1cccs1)N1CCCC(c2nnn(-c3cccc(Cl)c3)n2)C1 +O=C1NCCc2c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)[nH]c3cccc1c23 +CCC(NC(=O)c1ccc2c(c1)c(SC)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 +CCSCC1CC(O)(c2ccccc2)C(c2ccccc2)C(c2ccc(Cl)cc2)O1 +O=C(O)c1ccc(Cn2cnc3cnc(C(=O)NCc4ccc(C(F)(F)F)cc4)cc3c2=O)cc1 +COc1cc2c(Nc3nc4ccccc4s3)c(C#N)cnc2cc1OCCN1CCN(C)CC1 +NC(=O)C1CCCN1CCn1c(=O)nc(-c2ccccc2)c2oc3ccc(Cl)cc3c21 +OCCCCNc1cc(-c2cccc(NCc3cccc(F)c3)n2)c(Cl)cn1 +O=C(Cn1cnc([N+](=O)[O-])n1)N1CCC(Cc2ccccc2)CC1 +COc1ccc(-c2c(-c3cc(OC)c(OC)c(OC)c3)c(=O)c2=O)cc1N +CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCC(C)C +O=C(CC1CCCC1)c1c[nH]c2ccc(Cc3ccccc3)cc2c1=O +COc1ccc(Nc2ncc(C#N)c(Oc3cccc4c3C(=O)CC4)n2)cc1 +COc1cc(OC)c2c(c1Cl)OC1(C2=O)C(OCCc2ccccc2)=CC(=O)CC1C +O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(C#Cc2ccccc2)C(F)(F)F)cc1 +O=C(C=Cc1cccc2c1N(Cc1ccc3ccccc3c1)C(=O)C2)NS(=O)(=O)c1ccc(F)c(F)c1 +Cc1ccc(C(=O)NC(Sc2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1 +COc1ccc2[nH]c(-c3ncsc3N3CCN(C(=O)Cn4c(=O)n(C)c5ccccc54)CC3)nc2c1 +Fc1c(CN2CCCNCCNCCCNCC2)cccc1CN1CCCNCCNCCCNCC1 +Cn1c2c(c3cc(F)ccc31)CN(CCCC(=O)c1ccc(F)cc1)CC2 +O=C(Nc1ccc(Oc2ncnc3[nH]cnc23)c(F)c1)c1cccn(-c2ccc(F)cc2)c1=O +Cc1cn(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cn1 +CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C(C)=O)cccc32)c1 +CCCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)CNCC3)cc1 +COc1cc(-c2nc(C3CCC3)n3ccnc(N)c23)ccc1Oc1cccc(C)c1 +CC1CN(c2n[nH]c3cc(NC(=O)NC(c4ccc(F)cc4)C(C)(C)O)ncc23)CC(C)O1 +CN(C)Cc1ccn2c(-c3ccnc(NCc4ccc(Cl)cc4)n3)c(-c3ccc(F)cc3)nc2c1 +CN(c1ccc(NC(=O)C2CCCCC2)cc1OCc1ccccc1)S(C)(=O)=O +COc1ccc(-c2cc3ccccc3nc2C=CC(=O)c2ccc(F)cc2)cc1 +COCC1CNC(C)CN1CC(=O)N1CC(C)(C)c2cc(F)c(S(=O)(=O)c3ccccc3)cc21 +O=C(NS(=O)(=O)c1ccc(Br)c(Br)c1)c1ccc(Cl)cc1Cl +Nc1cc(C(=O)O)ccc1Cn1cc(-c2ccc(-c3ccccc3COc3cc(C(F)(F)F)ccc3Cl)cc2)nn1 +Cc1ccc(-c2ncccn2)c(C(=O)N2CCCC(Nc3ccc(C(F)(F)F)cn3)C2C)n1 +Cc1ccn(CC(=O)N2CCN(c3scnc3-c3nc4ccccc4[nH]3)CC2)n1 +CN1CCc2c(cccc2Nc2cnn(C)c(=O)c2Cl)C1 +COc1ccc(-c2c(F)c(C(=O)NN3CCCCC3)nn2-c2ccccc2Cl)cc1 +CCc1cn(Cc2c(C)cccc2C)c2cc(C(=O)O)ccc12 +CC(=O)N1CCN(c2ccc(CN(C(C)(C)C)S(=O)(=O)Cc3ccccc3)cc2)CC1 +O=C1N=C(N2CCCCC2)SC1=Cc1ccc(N2CCC(NCC(O)COc3ccccc3)CC2)cc1 +CC(=O)CCCC(=O)NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCCc2ccc3ccccc3c2)C1=O +CC(=NNC(N)=S)c1ccc2ncc(Cc3cc4cccnc4cc3F)n2n1 +CC(CF)n1cnnc1-c1cccc(N2Cc3ccccc3C2=O)n1 +COc1ccc(NC(=S)N2N=C(c3ccccc3O)CC2c2ccc(O)c(OC)c2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccc(F)c(Cl)c1)c1ccc(NS(C)(=O)=O)c(F)c1 +COc1cccc(C(CC(=O)NC(CC(C)C)B(O)O)NC(=O)Cc2cccc3c2CCCC3)c1 +OC1CCN(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncc2)CC1 +CCc1nc(C)c(CN2CCN(c3cccc4[nH]c(-c5ccc(C(C)(C)C)cc5)nc34)CC2)o1 +CN1CC2(CNC(=O)c3c2[nH]c2c3CCc3cnc(-c4ccccc4F)cc3-2)C1 +Cc1ccc2c(CC(=O)O)cn(-c3ccc(Cl)cc3Cn3c(C)nnc3C3CC3)c2n1 +CC(C)C(CNC(=O)c1nccnc1Oc1ccc(Nc2ccccn2)cc1)c1ccccn1 +COc1ccc(C23Oc4cc(OC)cc(OC)c4C2(O)C(O)C(C(N)=O)C3c2ccccc2)cc1 +CCCc1nc(-c2ccccc2)c(CNCCCN2CCN(c3cccc(C(F)(F)F)c3)CC2)o1 +O=C(O)COCC1CCC(COC(=O)N(c2ccccc2)c2ccc(F)cn2)CC1 +COc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)ccc1-c1nc(C2CCC3CCC(=O)N3C2)n2ccnc(N)c12 +N#Cc1nc(NCc2cccc(-c3cc(Cl)cc(Cl)c3)c2)c2ncn(CCCO)c2n1 +Cc1c(Cl)cccc1-c1nc(C2CCN2C(=O)c2cc(F)ccc2-c2ncccn2)no1 +CC(C)CC(NC(=O)CC(NC(=O)Cc1cccc2c1CCCC2)c1cccc(F)c1)B(O)O +CN1C2COCC1CC(NC(=O)c1cn(-c3cccnc3)c3ccccc13)C2 +O=C(NCCN1CCN(c2ccccc2)CC1)c1ccc(F)cc1 +OC(CNCCOc1ccc(-c2coc(COCc3ccccc3)n2)cc1)c1cccnc1 +CCOC1CCN(c2ccc(-c3cnnc4cc(OC)c(OC)cc34)cn2)CC1 +CC(=O)c1sc(NC(=O)NC2CCCOC2CN2CCCC(Cc3ccc(F)cc3)C2)nc1C +O=C1C(NS(=O)(=O)c2ccc3c(Cl)c[nH]c3c2)CCN1c1ccc(C2CCCN2)cc1F +Cc1cccc(-c2ccc(OCCCOc3ccc4c(c3)CCC4CC(=O)O)cc2)n1 +COc1cccc(OC)c1C(=O)NNC(=O)c1cccc(COc2ccc3c(c2)CCC3)c1 +CCC1(O)c2cc3n(c(=O)c2COC1OCC(F)(F)C(F)(F)F)Cc1cc2ccccc2nc1-3 +COc1cc(OCc2cccc(-c3ccc(F)cn3)c2)c2cc(-c3cn4nc(C(C)(F)F)sc4n3)oc2c1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cccc(Cc4ccccc4)c3)ccc2[nH]1 +CCCCCCCCCOc1cccc(C(SCCC(=O)O)SCCC(=O)O)c1 +CCc1cc2cc(C(=O)C3COc4ccccc4C3)ccc2nc1C +COc1cc2ncnc(N3CCC(Oc4ccc(OC(F)(F)F)cc4)C3)c2cc1OC +COc1cccc(-c2cccn3nc(Nc4ccc(C5CCN(C(=O)OC(C)(C)C)CC5)cc4)nc23)c1F +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c4c(ccc3nc2-1)OCCN4 +N=C(c1ccc(CN2CCN(S(=O)(=O)c3cc4cc(Cl)ccc4[nH]3)CC2=O)cc1)N1CCCCC1 +CSCCC(C(=O)NS(=O)(=O)c1ccccc1)N1C(=O)C(=Cc2ccc(-c3ccccc3)cc2)SC1=S +Cc1sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c(-c2nc(C3CC3)no2)c1C +CN1CCCC1C(=O)N1CC(COc2ccc(-c3nc(C#N)nc4c3ccn4C)cc2C(F)(F)F)C1 +CCCn1c(Oc2cccnc2Cl)nc2nc(C3CCCC3)[nH]c2c1=O +COc1cccc(Nc2cc(-c3ccncc3)nc3c2C(=O)NCC3)c1 +Cc1nn(Cc2ccc(NC(=O)OCc3ccccc3Br)cc2)c(C)c1CC(=O)O +OC1COC(n2cc(Cc3ccccc3)c3c(Br)cccc32)C(O)C1O +CCC(NC(=O)N1CCC2(CC1)C(=O)N(c1cccc(F)c1)C2c1ccc(Cl)cc1)c1ccccc1 +COc1ccc(Cl)cc1-c1cc(N(C)C)c(C(=O)N=C(N)N)o1 +CCc1cc(C)c(NC(=O)NCC2CCCO2)cc1C(=O)N1CCC(F)(c2ccc(C#N)cc2)CC1 +O=C(O)CC1CCCn2c1c(Sc1ccc(Cl)c(Cl)c1)c1c(C3CC3)nccc12 +COc1cnc2n1Cc1ccccc1C=C2N1CCN(CC(C)(C)C(=O)O)CC1 +CCOc1cccc(Oc2c(C(=O)O)n(-c3ccc(C(C)(C)C)cc3)c3ccccc23)c1 +CNc1cccn2c(=O)c(O)c(C(=O)NCc3ccc(F)cc3)nc12 +CCN(CC1CC(F)CN1)C(=O)c1ccc(-c2cnc3ccc(NCC4CC4)nn23)cc1 +CCC(C)C(CN(CC(=O)NC(CCSC)C(=O)O)Cc1ccccc1)NC(=O)CCS +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)CCc3ccccc3)c(F)c2)CC1 +OC1C(COC2CC2)OC(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C1O +CC(C)(C)OC(=O)Nc1ccc(CCN2CCc3ccccc3C2)cc1 +N#Cc1cc(S(=O)(=O)c2ccc(F)cc2)cc2c3c(oc12)CCNC3 +CC(C)C(C(=O)NO)N(CC#N)S(=O)(=O)c1ccc(OCCF)cc1 +CN(C)CCN1C(=O)c2cccc3cc4cc(O)ccc4c(c23)C1=O +CCCCCCC=CCCCCCCCC(=O)Nc1cccc(OP(=O)(O)O)c1 +CCN(CCCl)CCCCNc1c2ccccc2nc2ccc(OC)cc12 +CCN(c1nc(C)cc(C)n1)c1ccc(C(C)=O)cc1SC +CNC(=O)Nc1ccc(-c2cc(-c3ccnc(Nc4ccc(C)c(S(N)(=O)=O)c4)n3)ccn2)cc1 +CCSCC1OC(n2cnc3c(NC4CC5CCC4C5)ncnc32)C(O)C1O +Nc1nc(OCCc2c[nH]c3ccc(Cl)cc23)nc2c1ncn2C1OC(CO)C(O)C1O +COC(=O)C=Cc1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(Cl)cc1 +CC(NC(=O)c1cc(-c2ccc(OCC(=O)N3CCOCC3)cc2)cnc1N)c1c(Cl)ccc(F)c1Cl +O=C(Nc1cccnc1C(=O)N1CCCC1)c1nc(C2CC2)cnc1Nc1cncnc1 +CCOc1ccc(-c2ccc(Cn3c(CC4(C(=O)O)CCCC4)nc4cc(OCc5ccc6ccccc6n5)ccc43)cc2)cn1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nnc(Nc2ccccc2F)o1 +O=C(O)c1ccccc1Nc1nc(Nc2ccccc2)ncc1F +O=C(O)C=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +COCC(Cc1ccccc1)NC(=O)Nc1cc2[nH]nc(-c3ccnc(C)c3)c2cn1 +CCCN1CCN(c2nc(CCN(C)C(=O)c3ccc([N+](=O)[O-])cc3)cs2)CC1 +Fc1ccccc1Nc1nccc(-c2c[nH]c3ncccc23)n1 +COC(=O)c1cccc(-c2ccc(NCC(N)CS)cc2)c1 +O=C(C1CCc2c(Cl)cc(OCc3cc(F)cc(F)c3F)c(=O)n21)N1CCCC1 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+Cc1ccc(-c2noc(C3CCCC3)n2)cc1NC(=O)c1cnc2ccccn12 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3ccc(F)c(C)c3)ccc2[nH]1 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4Cl)no3)ccc21 +CCOc1cc2ncc(C#N)c(Nc3ccc(OC4CCc5ccccc54)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C +CNC(=O)N1N=C(c2ccc(N3CC4(CCS4(=O)=O)C3)cc2)c2cc(OC)c(OC)cc2CC1C +COC(=O)c1ccc(-c2ccc(OC)c(OC3CCCC3)c2)cc1 +CCOC(=O)C1=C(C)N=C(C[S+]([O-])c2ccncc2)C(=C(O)OCC)C1c1ccccc1C(F)(F)F +CC(C)(O)Cc1nnc2ccc(-c3c(-c4ccc(F)cc4F)nc4occn34)nn12 +CN(Cc1ccccc1)C(=O)c1cn2nc(-c3ccco3)nc2c(N)n1 +CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-c4cn[nH]c4)ccc3n2)cc1 +O=C(Nc1cn2nc(-c3cn(C4CC4)nc3-c3ccc(F)cc3)ccc2n1)c1csc(-c2ccncc2)n1 +CCCCCNc1nc(Nc2ccc([N+](=O)[O-])cc2)nc(OCC(F)(F)F)n1 +COC(=O)c1cn2ncnc(Nc3ccc(C)c(O)c3)c2c1C(C)(C)C +COC1CCC2(CC1)Cc1ccc(Br)cc1C21NC(=S)N(C2CCOCC2)C1=O +CC(c1ccc(-c2ccn(C3CC3)c(=O)c2)cc1)N1CCC2(CCC(O)C2)OC1=O +O=c1[nH]nc(Cc2cccc(CN3CCCC3)c2)c2c1CCCC2 +COc1cncc(-c2nc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)cs2)c1 +O=C(Nc1nc2cc(CN3CCOCC3)ccc2n1C1CCC(O)CC1)c1cccc([N+](=O)[O-])c1 +CCCSc1c(C(=O)NC2C3CC4CC2CC(OC)(C4)C3)cnn1-c1ccc(C(=O)O)cc1 +Cn1c(=O)c(F)c(Nc2ccc(I)cc2F)c2c(=O)n(CC(O)CO)cnc21 +Cc1cc2c(NC(=O)NC3CC(CF)(CF)Oc4cc(F)ccc43)cccc2cn1 +Cc1nc(C)c(CC(=O)Nc2cccc(CN3CCC(C(=O)NC(C)(C)C)CC3)c2)s1 +COc1c(C#Cc2ccc(NS(C)(=O)=O)cc2)cc(N2CCC(=O)NC2=O)cc1C(C)(C)C +Cn1nc2ccc(N3CCC(c4cc(F)c(F)cc4F)C(N)C3)nn2c1=O +CCCCCOc1c(OC)ccc2c1C(=O)N(CCc1ccc(O)cc1)C2=O +CC(C)(NCC(O)C(Cc1ccccc1)NC(=O)c1cccc(-c2ccccc2)c1)c1ccccc1 +CCCCCCCCC(=O)NCc1ccc(CC(O)CO)c(OC)c1 +O=C(NCCC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1)c1nn[nH]n1 +CC(C)(C)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(CC(=O)O)c2)cc1 +NC1(c2ccc(-c3nc4c5cc(-c6ccc(CO)cc6)ccc5nn4cc3-c3ccccc3)cc2)CCC1 +COc1cc2c(cc1CO)CCC1C(C)(CO)CCCC21C +O=C(CCCCCCc1ncc(-c2ccc(-c3ccc(Cl)cc3)cc2)o1)NO +COc1cccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)c1 +CCCC(C)(CO)NC(=O)c1cc(OCC2CC2)c(Cl)cn1 +COc1ccc2ncn(CC=C3c4ccccc4COc4ccc(C(=O)O)cc43)c2c1 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+CNC(=O)Nc1ccc2c(c1)C(=O)C(=Cc1c(-c3c(C)nn(C)c3C)[nH]c3ccc(OC)cc13)O2 +O=C1c2ccccc2C(=O)N1CCOC(=S)NC1CCCCC1 +CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)CS +c1ccc(-c2cc3nc(-c4ccco4)cc(N4CCNCC4)n3n2)cc1 +CCCc1c2c(nc(-c3ccccc3)c1C(=O)OCC)CCSC2=O +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3cc(C(=O)O)[nH]c3c2)cc1 +COc1ccc2[nH]c(C(=O)c3cc4ccccc4[nH]3)cc2c1 +O=C(N1CCN(Cc2ccc(Cl)cc2)CC1)n1nnc2ccccc21 +CCS(=O)(=O)NCC(C)(C)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1 +Cc1nc(C)c(-c2nnc(-c3ccc(OC(C)C)c(Cl)c3)s2)s1 +COC(=O)CCCN(C)CCCn1c(-c2ccccc2)cc(C(=O)Nc2cccc(C(F)(F)F)c2)c1C +NC(=O)NCc1noc(C(CCCC2CCCCC2)CC(=O)NO)n1 +COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)c(Br)cc1O +CN(C)CCC(CNC(=O)Nc1ccc(F)c(F)c1)c1ccc(-c2cccc(C#N)c2)cc1 +CCc1cccc(Oc2cccc(N(Cc3cccc(OC(F)(F)C(F)F)c3)CC(O)C(F)(F)F)c2)c1 +Cc1cn(-c2ccc3c(c2O)CCN(Cc2cccc(C(F)(F)F)c2)C3=O)cn1 +COCCN1CCC(NC(=O)c2cc(OC)c(Nc3ncc4c(n3)-c3c(nn(C)c3C(C)C)CC4)cc2Cl)CC1 +COC(=O)N1CCC(Cc2ccncc2)(c2ccc(OC)c(OC3CCCC3)c2)C1=O +Cc1cccc(C)c1-c1cccc(COc2ccc(CCC(=O)O)s2)c1 +Nc1ccc2c(c1)oc1c(N3CCC(N)C3)c(F)cc3c(=O)c(C(=O)O)cn2c13 +O=C(NCc1ccc(S(=O)(=O)N2CCOCC2)cc1)N1Cc2ccncc2C1 +CC(Nc1cc(N2CCOCC2)ncn1)C(Cc1ccc(Cl)cc1)c1cccc(Br)c1 +COc1cc(Sc2c(-c3ccc(F)cc3)[nH]c3ccccc23)cc(OC)c1OC +Cc1cccc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1 +Nc1ccn(C2OC(CO)(CCl)C(O)C2F)c(=O)n1 +Cc1cc(Cl)ccc1OC1CCN(CC2CCN(C(C)(Cc3ccc(F)cc3)C(=O)O)CC2)CC1 +CCCN(C1CCCC1)C1COc2cccc(C(N)=O)c2C1 +N#Cc1ccc(C(=O)NCC2CCN(c3ccncc3)CC2)cc1OCCc1ccc(Cl)cc1Cl +N#CCNC(=O)C1CCCCC1CSc1cc(Cl)c(Cl)cc1Cl +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC4CC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +FC(F)(F)c1ccc(CN2CCC(c3[nH]c(=S)n4cnc5[nH]ccc5c34)CC2)cc1 +O=C(O)CC(O)CC(O)CCn1c(C(F)(F)F)nc(-c2ccc(F)cc2)c1-c1cccc(Cl)c1 +O=C(NCC(=O)N1CCCC1)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 +COCCC(CC1(C(=O)NC2CC2c2ccc(F)cc2)CCCC1)C(=O)O +NCCCCC(NC(=O)C1CCC2CN(C(=O)CCc3ccccc3)CC(=O)N21)C(=O)c1nccs1 +Nc1ncnc2c1ncn2C1OC(COP(=O)(O)OP(=O)(O)OCC2NCC(O)C2O)C(O)C1O +CC(C)C(Oc1ccc(CNC(=O)C2SCCN2C(=O)CC(N)Cc2cc(F)c(F)cc2F)cc1)C(=O)O +CC(C)Cn1c(N)nc2ccc(-c3[nH]c(-c4c(F)cccc4F)nc3-c3ccccc3)nc21 +O=C(C1CC(N2Cc3ccccc3C2)CN1)N1CCSC1 +Cc1cc(N2CCOCC2)cc2[nH]c(-c3c(NCCn4ncc(Cl)c4C)cc[nH]c3=O)nc12 +COCc1cccc(CN2CCCC3(CCN(c4cnc5ccccc5n4)CC3)C2=O)c1 +COC(=O)c1c(C)[nH]c(C(=O)OCc2ccc(F)cc2)c1C +CCC(C)=CC=CC1CCC(=O)N1CCc1ccc(C(=O)O)cc1 +O=C(NC(c1cccnc1)C(F)(F)F)c1nc(N2CCOCC2)c2cnccn12 +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1CC(=O)N1CCOCC1 +COc1ccc(CCc2nnc(-c3ccc4[nH]cnc4c3)s2)c(OC)c1 +COc1cc(C(=O)O)ccc1Cc1nn(C)c2ccc(NC(=O)CC3CCCC3)cc12 +Cc1ccc(COc2ccc(S(=O)(=O)N3CCCC(C)(O)C3C(=O)NO)cc2)c(C)c1 +CCCCCCCOc1ccccc1NC(=O)OC(C)CN(CC)CC +O=C1C(=O)N(Cc2ccccc2F)c2ccc(S(=O)(=O)N3CCC3COc3ccccc3)cc21 +OC1CN(C2CCN(c3ccc(Nc4ncc5c6ccncc6n(C6CCCC6)c5n4)nc3)CC2)C1 +CN(C)c1ccc(C=Cc2ccc3ccccc3[n+]2C)cc1 +CCCOC(=O)c1cccc(Nc2nc(-c3cccnc3)nc3ccccc23)c1 +COc1ccc(CNC(=O)C2CN(c3cc(OC)nc(OC)n3)CCN2S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cc1 +CCCCCCN(C)C(=O)N1CCN(S(=O)(=O)c2ccc(Br)cc2)C(C(=O)NO)C1 +COc1ccc([N+](=O)[O-])cc1-c1ccc(C=C(C#N)c2nn(CCO)c(N)c2C#N)o1 +O=C(CCCCC(c1ccc(F)cc1)c1ccc(F)cc1)N1CCN(CC=Cc2ccccc2)CC1 +Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(c1)NC(=O)C21CCCC1 +Cc1nn(C)c(Oc2ccccc2)c1C(=O)N1CCCCC1c1cccnc1 +Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)N2CCSCC2)cn1 +CCCc1c(O)c(O)c(C(=O)O)c2cc(C)c(C)cc12 +O=C(CCc1ccccc1)c1ccccc1OCCCCCCN1CCCCC1 +O=C(OCCCCSc1nnc(-c2cccc3ccccc23)o1)c1ccc(F)cc1 +CCCc1cc(NC(CC(C)C)C(=O)NCCCOCC)nc(-n2cnc(-c3ccccc3OC(F)(F)F)c2)n1 +O=C1CCCN1CCCCN1CCN(C(c2ccccc2)c2ccccc2)CC1 +CN(c1ncnc2[nH]ccc12)C1CC(NS(=O)(=O)N2CC3CC3(C#N)C2)C1 +O=C1Cc2c([nH]c3ccc(F)cc23)-c2ncccc2N1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCCC2)cc1 +Cn1cc(C2=NCC3(CC4CCC(C3)N4Cc3ccccc3)O2)c2ccccc21 +CCCCN(CC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)c(C)nn12 +CCN(Cc1cccs1)C(=O)COc1ccc2c(c1)COC2 +Cc1cc(-c2nnn(CC3CCC(CO)CC3)n2)cc(C(=O)NCc2ccc(F)cc2)n1 +Cn1c(=O)nc2n(CCC3CC3)nc(-c3ccc4c(c3)OC(F)(F)O4)nc-2c1=O +O=C(NC(Cc1ccccc1)C(O)CN(OC1CCCCC1)S(=O)(=O)c1ccc2c(c1)OCO2)OC1COC2OCCC12 +O=C(Nc1ccc(N(CCCl)CCCl)cc1)Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1 +Oc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1CN1CCCC1 +COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(Cl)c2-c2ccccc2)nc1 +CCC(C)NC(=O)c1nn(-c2ccc(Cl)cc2)c(=O)c2ccccc12 +O=C1C(Cl)C(c2ccc([N+](=O)[O-])cc2)N1Nc1ccnc2cc(Cl)ccc12 +Cc1cccc2cc(C(=O)NC3CCN(C(C)C)CC3)n(CC(=O)Nc3ccc(Cl)cc3)c12 +CCCc1c(C(=O)Nc2cc(S(C)(=O)=O)ccc2C)cnn1-c1ccccc1 +CS(=O)(=O)c1cccc(Oc2cccc(-c3ccnc4c(Cl)cccc34)c2)c1 +CC(=O)NC(CNC(=O)c1cc2n(n1)CCN(CCC1CCNCC1)C2=O)C(=O)O +Cc1cccc(-c2cccc(NCc3cncn3Cc3ccccc3)c2)c1 +O=C(Nc1ccc(C2=NCCN2)cc1)c1ccc(C(=O)Nc2ccc(C3=NCCN3)cc2)cc1 +CC(C)(C)c1ccc(-c2ccc(-c3nc4cc(C=C5SC(=S)NC5=O)ccc4[nH]3)o2)cc1 +CN(C)CCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1 +O=C(C1CC(N2CCN(c3cnccn3)CC2)CN1)N1CCC(F)(F)C1 +O=C(Cc1ccccc1B(O)O)N1CCC(Oc2ccc(C(F)(F)F)nc2)CC1 +Cc1ncc2cc(C(=O)Nc3cc(C(=O)NC(CCN)c4ccccc4)ccc3Cl)c(=O)[nH]c2n1 +O=C(Nc1ccc(C2CCNC2)cc1)Nc1ccc(Cl)cc1Cl +CCNC(=O)Nc1nc2cc(-c3ccc(=O)n(CCOC)c3)c(=O)n(C(C)C)c2s1 +CCc1cc(CC2CS(=O)(=O)CC(NCc3cccc(C(C)(C)C)c3)C2O)cc(F)c1NC(C)=O +COc1ccc(S(=O)(=O)N2CCc3cccc(-c4ccc(F)nc4)c32)cc1 +COc1ccc(CCO)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(NC(=O)CN(C)C)cc2)c1 +Cc1cc2cc(C(N)=O)c(N)nc2nc1C(F)(F)F +COC(=O)C1C(O)C2(O)c3c(cc4c(c3OC)OCO4)OC2(c2ccc(OC)cc2)C1c1ccccc1 +CC1=CC2OC3CC4OC(=O)C=CC=CC(=O)OCCC(C)C(O)C(=O)OCC2(CC1)C4(C)C31CO1 +Cn1cc(-c2cc(S(=O)(=O)N3CCc4ccccc43)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +CC1(c2cc(Nc3nc(N4CCN(C(=O)Cc5ccccc5)CC4)nn4cccc34)n[nH]2)CC1 +CCC1CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 +NCCCCNC(=O)C1C(C(=O)Nc2ncc(Br)s2)C2CCC1C21CC1 +COc1ccc(Nc2nc(N3CCCCC3)nc3ccccc23)c(OC)c1 +CN1CCC(Cn2c(N)nc3ccc(C(=O)c4ccccc4)cc32)CC1 +Cc1ncc(C(CNC(=O)c2cccc(Cl)c2Cl)N2CC(F)(F)C(F)(F)C2)cn1 +Cc1nn(Cc2ccc(-c3nc4c(F)cc(F)cc4[nH]3)cc2F)c(C)c1CC(=O)O +CC1CN(C(=O)N2Cc3c(C(=O)OC(C)(C)C)ncn3-c3ccc(Cl)cc32)CC(C)N1 +CCOC(Cc1ccc(OCc2nc(-c3ccc(-c4ccccc4)s3)oc2C)cc1)C(=O)O +CCOC(=O)c1ccc(N2CCC(OC(=O)N3CCN(C(C)C)CC3)CC2)nc1 +CCn1c(NC(C)C)nc2c(C3CCN(C(=O)c4ccccn4)C3)csc2c1=O +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(-c2ncccn2)nc1OCCOC(=O)Nc1ccccn1 +COc1cc(C)cc(OC)c1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 +COc1cc(Cl)ccc1CC(C)C(=O)N1CCN(c2ccc(Cl)cc2C(N)CC(C)C)CC1 +Nc1ccc2c(c1)CC(n1nc(-c3cc(F)c4c(c3)NCCO4)c3c(N)ncnc31)C2 +NS(=O)(=O)c1ccccc1N1C(=O)c2c(Cl)c(Cl)c(Cl)c(Cl)c2C1=O +Brc1ccc2cc(CCc3cc4ccc(Br)cc4[nH]3)[nH]c2c1 +O=C(NCCCN1CCCC1=O)C1CC1c1ccc(Sc2ccccc2N2CCCC2)c(C(F)(F)F)c1 +Cc1ccc(-c2ncc(C(=O)c3ccc(F)cc3)n2S(=O)(=O)c2ccccc2)cc1 +CNC(=O)c1ccc(C)c(Nc2ncnc3c2cnn3-c2ccc(F)cc2)c1 +Cc1ccsc1C(=O)NC1CCC(CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1 +Cc1cnc(-c2cc(N3CCn4cc(C(=O)Nc5cccnc5)nc4C3)ncc2Cl)c(C)c1 +O=C1NC(C(=O)O)Cc2cn(nn2)CCCCOc2ccc(Cl)c1c2 +CCCn1c(=O)c2nc(-c3cnn(Cc4noc(-c5ccc(C(F)(F)F)cc5)n4)c3)[nH]c2n(CCC)c1=O +CCCc1cc(-c2nc(OCC)cs2)ccc1OCCCOc1ccc2c(c1)CCC2CC(=O)O +COc1ccc(-c2c(SCc3ccncc3)oc3cc(O)ccc3c2=O)cc1 +CC(C)N1CCC(NC(=O)c2cc3c(Cl)cccc3n2Cc2cc(-c3ccc(Cl)s3)on2)CC1 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1n[nH]cc1Nc1ncnc2[nH]ccc12 +Cc1cc2c(s1)Cc1c(C(=O)NN3CCCCCC3)nn(-c3ccc(Cl)cc3Cl)c1-2 +Cc1cccc(C)c1Oc1c(C(=O)N2CCNCC2)c2ncc(O)cc2n1-c1ccccc1 +CCCCCCCNC(=O)Nc1cc(C=CC(=O)NO)ccc1OCCN(CC)CC +COc1ccccc1CNCCc1ccc(NC(=O)Nc2cnc(C#N)cn2)cc1Cl +CC(C)(C)C(=O)N(CCCCCCN1CC(O)C(O)C(O)C1CO)C1CCCCC1 +O=C(Nc1ccc(Br)cc1)NC(c1ccc(Br)cc1)c1ccc(Br)cc1 +Cc1ncc(Cl)cc1C(=O)NC1CCC(Cn2nc(-c3cccnc3)cc2C)CC1 +COc1ccc(Nc2nccc3ccn(S(=O)(=O)c4ccc(OC)cc4)c23)cc1 +c1ccc(CN2CCC(c3cc(-c4ccccc4)[nH]n3)CC2)cc1 +CC(C)n1c(=O)c2c(-c3ccc(F)cc3)ncn2c2cccc(Cl)c21 +N#Cc1ccc2c(NC3=NCC4(CN5CCC4CC5)O3)ncnn12 +Cc1ccc(C(=O)Nc2cccc3cc(Oc4cncc(C(N)=O)c4)ccc23)cc1[N+](=O)[O-] +c1ccc(CNc2ccsc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)nc1 +CCOC(=O)N1CC(C(=O)Nc2ccc(Cl)cc2)C(C(=O)Nc2ccc(-n3ccccc3=O)cc2F)C1 +COc1cc(NC(=O)c2cc3nc(C)cc(C)n3n2)c(OC)cc1Cl +CNc1n[nH]c2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 +Cn1nc(C(=O)N2CCN(CC(=O)c3ccc(F)cc3)CC2)cc1-c1ccco1 +Clc1cccc(Nc2nc(-c3ccccc3)nc3ncccc23)c1 +O=C(O)c1ccoc1-c1cccc(NCCNCC(O)c2cccc(Cl)c2)c1 +CCCOc1cc(C#N)cc(OC)c1Oc1nc(Nc2ccc(C#N)cc2)nc2ccccc12 +COC(=O)c1cc(-c2ccc(Cl)c(Cl)c2Cl)[nH]n1 +Cc1ccc(S(=O)(=O)NC(=O)N2CCC(N3CCC(Oc4ccc(Cl)c(Cl)c4)CC3)CC2)cc1 +O=C(O)C1CCN(c2ccc(-c3c(C=Cc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cc2)CC1 +Cc1cc(C)c(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(-c2ccccc2)c1 +CCCOc1cc(C)c2c(c1C)CC(C(C)C(=O)Nc1ncc(C)s1)CC2 +NC(=O)c1ccc(-n2c3c(c4cc(F)ccc42)C(=O)CCC3)cc1NC1CC1 +COc1ccc(C2=NC(=O)C(=Cc3cc(OC)c(OC)c(OC)c3)O2)cc1 +CC1CN(Cc2ccc(NS(=O)(=O)c3ccc(-c4ccc(F)cc4)nc3)cc2C(F)(F)F)CCN1 +O=S(=O)(c1ccccc1)c1cc(OC(F)(F)F)c2oc3c(c2c1)CNCC3 +COc1ccc(Cn2c(CCc3c[nH]c4ccccc34)nnc2C(NC(=O)Cc2ccccn2)c2c[nH]c3ccccc23)cc1 +O=C1OC2(CN3CCC2CC3)CN1c1ccc2ccccc2n1 +COc1cc(CC(=O)O)ccc1Oc1ccc(C(=O)NC2CCC2)cc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1Cl +c1ccc(CCNc2ncnc3nc(-c4ccc(N5CCOCC5)nc4)cnc23)cc1 +CC(C)(CO)CNC(=O)c1cc2cc(C#N)ccc2n1Cc1cc(Cl)cc(Cl)c1 +CCCS(=O)(=O)Nc1ccc(F)c(-c2cc3cncc(Br)c3cn2)c1F +O=C(CCCN1C2CCC1c1c([nH]c3ccccc13)C2)c1ccc(F)cc1 +CC(C)CC(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C2CCOC2c2ccc(Cl)cc2)CC1 +OCC(Nc1cncc2nnc(-c3ccc(OC(F)F)cc3)n12)c1ccc(F)c(F)c1 +COC(=O)c1cccc(Nc2nc(-c3cccnc3)nc3ccccc23)c1 +Cn1ncc2cc(Cc3n[nH]c4ccc(C(=O)N5CCC(F)(F)C5)cc34)ccc21 +Cc1ccccc1COCC(C#N)NC(=O)C(CC(C)(C)C)NC(=O)N1CCOCC1 +CCCCC12CCC(=O)C(C)=C1c1ccc(O)cc1C2 +COC(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)(c1ccc(F)cc1C)c1ccc(F)cc1C +COc1ccc2[nH]cc(CCn3cc(NC(=O)c4ncoc4-c4ccccc4)cn3)c2c1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc([S+]([O-])c3ccccc3)ccc21 +COCCOc1cc2ncnc(Sc3nc(C)c(CC(=O)Nc4cccc(C(F)(F)F)c4)s3)c2cc1OCCOC +NC(=O)c1c(Nc2cc(Cl)c(N3CCNCC3)c(Cl)c2)nc(Cc2c(Cl)cccc2Cl)n2cnnc12 +Cc1ncn(-c2ccc(Nc3nccc(-c4cc[nH]n4)n3)cc2)n1 +CC(C)c1ccc(NC(=O)C=CC(=O)c2cccc3c2CCCC3)cc1 +COc1cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncco5)ccc43)cc2F)ccc1Cl +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2ccc(-c3ccccc3)cc2)cc1 +CC(Oc1cc(-c2ccc3c(c2)ncn3C)cc2ncccc12)C1CNC(=O)C1 +Cc1ccc(C2C(=O)Nc3ccc(-c4cncc(OCC(N)Cc5c[nH]c6ccccc56)c4)cc32)o1 +CC(C)C(NC(=O)Cn1ccc2c(=O)n(-c3ccccc3)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +C#CCNc1ncnc2sc3c(=O)n(-c4ccc5ncsc5c4)cnc3c12 +COc1ccccc1N1CCN(CCCNC(=O)c2ccc[nH]2)CC1 +O=C(O)c1nc2c(O)nc3cc(C(F)(F)F)c(-n4cccc4)cc3n2n1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCCCC2)C1=O)c1ccccc1 +O=C(NS(=O)(=O)c1ccc2ccccc2c1)c1cc2ccccc2n1Cc1cccc(C(F)(F)F)c1 +Cc1cc(C)cc(-c2c(O)nc3cc(Cl)c(C(=O)Nc4ccncn4)cc3c2OCCC2CCCC(C)N2)c1 +CC(C)(CNC(=O)c1cccc(C(F)(F)F)c1)CN(C1=NS(=O)(=O)c2ccccc21)c1ccccc1 +O=C(Nc1cc(-c2ccccc2)ccc1O)c1ccccn1 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCC2CCCOC2c2ccccc2)cc1F +COCC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)cn3)c2)c2cnc(N)nc21 +CC(C)(CCCON=C(c1ccccc1)C(Cc1ccccc1)n1ccnc1)C(=O)O +CC(=O)NC(C)Cc1ccc(C#Cc2cnc(OCc3cccc(F)c3)nc2)cc1 +CN(C)c1ccc(C=Cc2sc3ccccc3[n+]2Cc2ccc3ccccc3c2)cc1 +COc1cccc(CCNC(=O)CC(O)C(COCc2ccc(Br)cc2)NC(=O)c2c(F)cc(F)cc2F)c1 +NCCCn1cc(-c2ccc3ccc4ccc(-c5cn(CCCN)nn5)nc4c3n2)nn1 +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc(C(C)=O)cc4)c3c2)C1 +N#Cc1c2n(c3c(N4CCN(CCc5cccc(Cl)c5)CC4)ncnc13)CCCC2 +CC(C(=O)N(C)O)c1ccc(OCc2ccccc2)cc1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OCc3ncco3)cc2n1Cc1ccccc1 +CN1CCC(CCNCC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)C1 +CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCC(C(C)(C)O)CC3)[nH]c2n1 +O=C1NCc2cccc(c2)CNC(=O)c2coc(n2)-c2csc(n2)-c2cccc(n2)-c2nc(co2)-c2nc1co2 +NC(=O)c1nc(Nc2ccc3cnccc3c2)sc1NC(=O)c1ccsc1 +Cc1ccc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCCC3)nc12 +Cc1nc(N)ncc1CNC(=O)Cn1c(C)ccc(NS(=O)(=O)Cc2cccc3c2OCCO3)c1=O +O=C1NC(NCc2ccccc2)=NC1=Cc1c[nH]c2ncc([N+](=O)[O-])cc12 +c1cc2c(ncn3nnc(C4CCC(CN5CCOCC5)CC4)c23)[nH]1 +CN1CCN(c2ccc(Nc3ncc4c5cc[nH]c(=O)c5n(C5CCCC5)c4n3)nn2)CC1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NS(=O)(=O)c1ccc(C)cc1 +NC1(c2ccc(-c3nc4ccc(-n5cccn5)cn4c3-c3ccccc3)cc2)CCC1 +COc1ccc(C(=O)c2cn(CC3CCCCN3C)c3ccccc23)c2ccccc12 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cnc(C#N)cc1c2C +Cn1ccnc1S(=O)(=O)Nc1cccc(C(c2c(O)cc(C(CC3CC3)CC3CC3)oc2=O)C2CC2)c1 +N=C(c1ccc(C(=O)N2CCN(S(=O)(=O)c3cc4ccc(Cl)cc4s3)CC2)cc1)N1CCCCC1 +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3ccccn3)sc2c1 +COc1cc2nc(Sc3nnc(N)s3)n(-c3ccc(Oc4ccccc4)cc3)c(=O)c2cc1OC +CC1(C)CCC(C)(C)c2cc(C=CC(=O)NCc3ccc(NS(C)(=O)=O)c(F)c3)ccc21 +COc1cccc(CNC(=O)Nc2nc(-c3ccncc3)cs2)c1 +Cc1cncc(-c2cnc(NC3CCNCC3OCC3CCS(=O)(=O)CC3)c3[nH]c(=O)c(C)cc23)c1 +CN1C2CCC1CC(NC(=O)c1cccc3[nH]cnc13)C2 +COc1ccc(-c2ccc3ncnc(Oc4cccc(O)c4)c3c2)cc1 +Cc1cc(C)cc(-c2cnc3cc(Cl)c(-c4ccc(Cl)nc4)cc3c2OCCC2CCCCN2)c1 +CC(C)CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1C(=O)N(C)N(C(C)C)C(=O)c2ccccc21 +[N-]=[N+]=Nc1ccc(I)c(-c2cc(Cc3ccncc3)cc3cccnc23)c1 +O=C(Nc1cccc(Oc2ccc3c(C=Cc4c[nH]cn4)n[nH]c3c2)c1)c1ccccc1 +O=C(NCC1CC1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +CCc1cc(CNc2nc(Nc3cc(C4CC4)n[nH]3)cc(N3CCN(C)CC3)n2)on1 +CCCC[S+]([O-])c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N +Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCCc1ccncc1 +O=C(Nc1ccc(-c2cc(N3CC4CCC(C3)O4)c3nccn3n2)cc1)Nc1cccnc1 +O=C(O)c1ccnc2cc(C(OCCCN3CCCCC3)c3ccccc3Cl)[nH]c12 +O=C(O)CCCC(=O)N1CCC2(CC1)CCN(c1ccncc1)CC2 +CCN(CC)CCCNc1cc(-c2cccc(F)c2)c(C#N)c2nc3ccccc3n12 +Cc1c(-c2nsc(N(C)C)n2)sc(NC(=O)C2=C(C(=O)O)CCC2)c1-c1nc(C2CC2)no1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NC4CCC(NS(=O)(=O)CCC(F)(F)F)CC4)nc23)N1 +O=C(Nc1ccc(CCC2CCCCN2)cc1)c1ccc(Cl)cc1 +O=C(O)CC(=O)N1CCC(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(C2CCCCC2)cc1 +CCC(c1ccc(-c2ccc(F)cc2)cc1)N1CCC(CCCO)(c2ccccc2)OC1=O +Cc1ccc(NC(=O)Nc2cc(-c3cc(Cl)cc(C(=O)O)c3)ccc2Oc2ccccc2C(C)(C)C)cc1 +CCCN(CCN1CCN(c2ccc(-c3ccccc3OC)cc2)CC1)C1CCc2nc(N)sc2C1 +O=C(Cc1ccc(O)cc1)Nc1nc(-c2ccncc2)cs1 +O=C1NC(=O)C2=C1c1cn(c3ccccc13)CCOC(CN1CCOCC1)CCn1cc2c2ccccc21 +Cc1cncc(C2C(C#N)=C(N)Oc3cc(N(C)C)ccc32)c1 +CC1CCC2C(C)C(OCc3cccc(CN4CCN(c5ccc(Cl)cc5)CC4)c3)OC3OC4(C)CCC1C32OO4 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(CN5CCOCC5)s4)nc23)N1 +O=C(C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2)Nc1cccc(F)c1 +CCCCNC(=O)c1ccc2c(c1)nc(NC(=O)c1cccc(C#N)c1)n2CCCOC +COC(=O)N1CCOC(C(=O)N2CCC(c3cc(-c4ccncc4)c(-c4ccc(F)cc4)[nH]3)CC2)C1 +C=CCN1CCC23c4c5ccc(O)c4OC2c2c(c4ccccc4n2C)CC3(OC)C1C5 +CCC(Nc1ccc(Cl)c(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 +Cc1ccc(C2(c3nc4ccc(N5CCCC(C(=O)N6CCCC6)C5)nc4[nH]3)CC2)cc1 +CC(C(=O)OC1C[N+]2(CC(=O)Nc3cncc(Cl)n3)CCC1CC2)(c1cccs1)N1CCCCC1 +CC(C)Nc1nc2ccc(C#N)cc2nc1N1CCC(C(F)c2ccc(F)cc2F)CC1 +NC1CCC(Nc2nccc(Nc3cc(C4CC4)[nH]n3)n2)CC1 +CC1(C)SCN(CCCCN2CCN(c3cccc(C(F)(F)F)c3)CC2)C1=O +Cc1ccc2cc(C(=O)NC3(C(=O)NC(CCCN4CCN(Cc5ccsc5)CC4)Cc4ccccc4)CCCC3)sc2c1 +CN(C)C1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCOC5)c4n3)nc2)CC1 +NS(=O)(=O)c1ccc(CNC(=O)OCCCCc2ccc(N(CCCl)CCCl)cc2)cc1 +CC(=O)N1Cc2cc(-c3ccc(C#N)cc3)ccc2CCc2cc(Cl)ccc21 +N#Cc1c(-c2ccc(S(=O)(=O)NC(CO)CO)cn2)n(C2CCC2)c2cc(OC(F)F)ccc12 +COC1CCC(=Cc2sc(-c3ccc(C)cc3)nc2O)CC1 +Cc1cccc(NC(=O)c2nccc3c(-c4ccccn4)c[nH]c23)n1 +CCCCc1nn(C(C)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCS(=O)(=O)CCCc1ccc(-c2nnc(-c3ccccc3C(F)(F)F)n2C)c(C)c1 +CCCCCn1c2ccccc2c2cc(CN3CCN(C)CC3)ccc21 +Cc1ncc(-c2ccc(C(=O)N=c3[nH]c4cc(CN(C)c5ccccc5)ccc4n3CC(C)(C)O)s2)o1 +CC(=O)OCCOc1ccc2c(c[n+](C)c3c4cc5c(cc4ccc23)OCO5)c1O +COc1ccc(CNC(=O)Nc2cc(-c3cccnc3F)ccn2)cc1 +COCCN(C(=O)c1cnc(-c2cccc(C)c2C)cn1)c1ccc(OC)nc1 +CC1CCCN1CCc1cc2cc(Nc3ccc([N+](=O)[O-])cn3)ccc2o1 +CCOc1ccc(-n2c(C)c3c(C)nnc(NC4CCc5ccccc54)c3c2C)cc1 +COc1ccc2cc(O)c(C(=O)NCc3ccc(Cl)cc3)cc2c1 +COc1ccc(OCC(=O)Nc2cccc(-c3nc4ncccc4o3)c2)cc1 +Cc1nc2cnc3ccc(C#CCNC(=O)c4cccn(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C(C)C +NC1=NC(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)(C(F)F)C2CC2O1 +[C-]#[N+]c1ccc(N2C(=S)N(c3ccc(C)cc3)C3(CCC3)C2=NC)cc1C(F)(F)F +c1ccc(Cn2ccc3nc(-c4ccccc4)nc-3c2)cc1 +O=C(c1ccccc1-n1nccn1)N1C2CCC1C(Nc1nc3cc(Cl)ccc3o1)C2 +N#Cc1ccc2[nH]c(C3CCC4(CC3)CN(c3ccccn3)C(=O)O4)nc2c1 +Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(C)c3ccc(C(C)C)cc3)cc12 +O=C(NO)C1CCCC1C(=O)Nc1ccc(OCc2cc(Cl)cc(Cl)c2)cc1 +CC(O)(c1ccc(C(=O)N(CC2CC2)C2CCCCC2)cc1)C(F)(F)F +CCOC(=O)C1=C(Nc2ccc(C)c(C)c2)SCC1=O 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+Clc1cccc(C(Nc2ccnc3cc(Cl)ccc23)c2ccc(CN3CCN(c4ccnc5cc(Cl)ccc45)CC3)c(Cl)c2)c1 +CCCN(CCC)C(=O)C1CCC(NC(=O)c2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CN1Cc1c(F)cccc1OC +CC(C)C(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1N1CCC(CN2CCCC2)CC1 +CC1CN(Cc2ccccc2)c2ccccc2C(C)N1C(=O)NC1COC1 +O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(Cl)c1 +CC1CC1C(=O)Nc1snc(-c2ccc3nn(C)cc3c2)c1-c1cccc(C2CCC2)n1 +CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(N)=O)cc2C4)cc1 +Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(O)c(O)c3)C(C)(C)C2=O)cn1 +COc1cc2nc(N3CCN(C(=O)C4COc5cccc(OC)c5O4)CC3)nc(N)c2cc1OC +CCOC(=O)C1CCC(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)CC1 +NCc1ccc(Oc2cc(Oc3ccc(CN)cc3)cc(C(=O)NC3CCC(N)CC3)c2)cc1 +NC(=O)c1cc(-c2ccncc2)[nH]c1-c1cccc([N+](=O)[O-])c1 +CCCc1cnc(N2CCC(C3Cc4c(F)c(C5=CCN(S(=O)(=O)CCC(C)(C)O)CC5)cc(F)c4O3)CC2)nc1 +CCCN(CCC)CCc1ccc(OC)cc1OCCc1ccccc1 +CN1CCNC(C(=O)NC(Cc2ccc(F)cc2)C(=O)N2CCC(CC3CCC3)(C(=O)NC(C)(C)C)CC2)C1 +COc1cc(-n2c(SCc3c(F)cccc3Cl)nc3c2C(c2ccc(Cl)c(OC)c2)CCC3)ccc1F 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+O=C(O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(CC(=O)O)c4)s3)s2)c1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3ccccn3)cc2)C(=O)C(C)C)c1 +COCn1c2c(c3ccccc31)CCN(CCCCC13CCCc4cccc(c41)NC3=O)C2 +CC1CC(C)CN(Cc2ccc(-c3cnc4[nH]c5cnc(C#N)cc5c4c3)cc2)C1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(F)cc2)cc1)P(=O)(O)O +CCCCSc1nc(Nc2cccc(O)c2)c2cnn(CC(Cl)c3ccccc3)c2n1 +COc1ccccc1Oc1c(NS(=O)(=O)NCc2ccccc2)nc(C2CC2)nc1OCCOc1ncc(Br)cn1 +OC1CN(Cc2cccc(Br)c2)CCC1N1CCN(c2ccccc2)CC1 +O=c1cc(OCc2ccccc2)ccn1-c1ccc(OCCN2CCCCC2)cc1 +CCc1nc(N)nc(N)c1C#CC(C)c1ccc(-c2ccccc2)cc1OC +CCc1ccccc1NC(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CC(C)(C)c1nnc(NC(=O)c2ccc3c(c2)OCCO3)s1 +Cc1c(C(=O)NC(C)(C)c2noc(C(F)(F)F)n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCC(CC)CNC(=O)C1C(C(=O)NCCCCN2CCCC2)C2C=CC1C21CC1 +Cc1c(-c2nnnn2Cc2ccccc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1ccc(-n2nc(C3CCN([S+]([O-])c4sc(C)nc4C)CC3)cc2NC(=O)c2cnn3cccnc23)cc1 +Cc1ccc(C(c2ccccc2)N2CCN(C(=O)CC(c3ccccc3)c3ccccc3)CC2)c(C)c1 +COc1nc2ccc(F)cc2nc1NC(=O)N1CCN(c2cc(C)cc(C)c2)CC1 +O=C1C(Nc2ccccc2Br)=C(Cl)C(=O)c2ncncc21 +c1ccc2ncc(Nc3ccnc(Nc4ccc(OCCCN5CCCCC5)cc4)n3)cc2c1 +COc1ccc(S(=O)(=O)n2cc(C3CCCNC3)c3ccccc32)cc1 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCC(O)C2)c(-c2cccnc2F)c1 +CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc4c(c3)CNC4=O)cc2s1 +COc1cc(=O)n2c3c(cccc13)OC(C1=NCCN1)C2 +Cc1cc(CC(=O)O)ccc1-c1ccc(-c2nc(C(N)=O)c(C)nc2C)cc1 +c1ccc(-c2[nH]c3ccccc3c2-c2ccccc2)cc1 +CN(C)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1 +OCC(O)CN1C(CCc2ccc3c(c2)OCO3)CCCC1CCc1ccc2c(c1)OCO2 +NS(=O)(=O)c1cccc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)c1 +O=C(c1ccccc1F)c1cc(F)ccc1C=COCCN1CCCC(C(=O)O)C1 +O=C(O)c1cc2[nH]c(-c3ccc(OCc4cccc(C(F)(F)F)c4)cc3)c(C3CCCCC3)c(=O)n2n1 +COc1cc(CN2CCOC(COc3ccccc3)C2)ccc1Cl +CC1(C)CC2CC(C)(CN2C(=O)c2cc(Cl)c(-c3cccc4ccccc34)cc2Cl)C1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1csc(-c2ccccc2)n1 +CNC(=O)c1ccccc1Nc1cc(Nc2ccc(N3CCOCC3)c(C)c2)ncc1C(F)(F)F +COc1ccc(CNC(=O)c2ccc(OC)c(OC3CCCC3)c2)c(C(F)(F)F)c1 +N#CCC1(n2cc(C(N)=O)c(Nc3cncc(F)c3)n2)CCN(C(=O)OCC(F)(F)F)CC1 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+Nc1ccccc1NC(=O)c1ccc(CNC(=O)CN2C(=O)C3(OCCCO3)c3cc(Cl)ccc32)cc1 +Cc1cc(C(=O)Nc2ccc(CN3CCCC3)cc2)nn1Cc1cc(Cl)ccc1OCc1ccccc1 +CC(CO)CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(C)c1=O +O=C1C(O)CC(c2c(F)cccc2OCCF)N1Cc1ccc(OC(F)(F)F)cc1 +CCCCP1(=O)OC(C2COC(C)(C)O2)C2OC(C)(C)OC2C1O +CN1Cc2c(C3=CCC(NC(C(=O)O)C(C)(C)C)CC3)[nH]c3nccc(c23)-c2cc(F)ccc21 +Cc1nc(-c2cccnc2Nc2cccc3[nH]ccc23)c2[nH]cnc2n1 +CCNC(=O)Nc1cc2c(-c3cnn(C)c3)ccc(C)c2cn1 +CCC(C)OC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(Cl)cc3)C2)C1c1ccccc1F +O=C(CCCCCCc1ccccc1)c1nc(-c2cccc(I)n2)no1 +CCn1cc(N2C(=O)c3nc(-c4ccccc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2C)cc(Cl)c1=O +O=S(=O)(Nc1ccc(CCNCC(O)c2ccccc2)cc1)c1ccc(Cc2nc(-c3cc4ccccc4o3)cs2)cc1 +CC1CC(NC(=O)c2cccc(-c3cccc(Cl)c3)n2)CCO1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(CO)c(S(=O)(=O)NC3CC3)c2)n1 +Cc1cc(C=CC#N)cc(C)c1Oc1cc(Nc2ccc(C#N)cc2)c(N)cc1CO +COc1ccccc1N1CCN(CCC(Oc2ccc3c(c2)OCO3)c2ccccc2)CC1 +CN1CCN=C1c1cccc(Oc2nc(Oc3cc(C(=N)N)ccc3O)c(F)c(N(C)CC(=O)O)c2F)c1 +c1ccc2oc(CNCCCCCCNc3c4c(nc5ccccc35)CCC4)cc2c1 +CCOC(=O)c1nnn(-c2ccccc2Br)c1C(O)C(O)C(C)O +Cc1cc(Nc2nc(NCc3ncccc3C)ncc2Br)n[nH]1 +CN(C)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 +Cc1cc(CCNCc2ccc3ccc(N)nc3c2)ccc1C#N +O=C(NC1CCCC1)c1cc(-c2ccc(C(F)(F)F)cc2)on1 +C=CCN1CCC23c4c5cccc4OC2C(O)CCC3C1C5 +C1CCN(CCCOc2nc3c(s2)CCN(CCCN2CCCCC2)C3)CC1 +CSc1ccc(OCc2ccc(F)cc2)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 +CN1CCC23c4c5ccc(O)c4OC2C2(CCC3(O)C1C5)CO2 +CCCc1ccc2c(c1)sc(=O)n2CCCCN1CCCCCC1 +O=C(NCCN1CCOCC1)c1ccc2c(c1)CC(c1nc3ccc(-c4cn[nH]c4)cc3c(=O)[nH]1)CO2 +COc1ccc(-c2ccc(-c3ccc(OC)c(OC)c3)o2)cc1OC +Cc1cccc(Sc2c(C(=O)NCCO)[nH]c3ccc(Cl)cc23)c1 +CC(C)n1nc(-c2cnc(N)c(C(F)(F)F)c2)cc1C1CCN(C2COC2)C1 +NC(=O)c1cc(-c2ccc(Cl)cc2)nc2c1[nH]c1cc(C(=O)N3CCOCC3)ccc12 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccnc(NN)c3)nc2n1 +CN1CCN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCCC3)CNC5=O)nc2)CC1 +O=C1NCN(c2ccc(Cl)cc2)C12CCN(C1CCCCC1(O)c1ccc(F)cc1)CC2 +COC(=O)C(NC(=O)c1cc(-c2ccc(O)cc2)nc2ccccc12)c1ccccc1 +COc1cc2nccc(Oc3ccc(NC(=O)NC4CCCCC4)cc3)c2cc1OC 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+CCCSc1nc2c(C)cc(C(=O)NCC(C)c3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=S(=O)(Nc1n[nH]c2nc(Oc3ccc(F)cc3F)ncc12)c1ccccc1 +N#Cc1cc(N2CCOc3cc(S(=O)(=O)Nc4nccs4)ccc32)ccc1F +N=C(N)NCCCC(NC(=O)CN1CCCC(CCC2CCNCC2)C1=O)C(=O)c1nccs1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc(Nc3ncnc4ccc(N)cc34)c2)cc1 +Oc1ccc(C2Nc3ccc4ccccc4c3C3C=CCC32)cc1 +COc1ccc2c(c1)C(=O)C(c1ccc(N)cc1)=[N+]2[O-] +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1ncnc2c(N)nc(N3CCN(C(C)C)CC3)nc12 +CS(=O)(=O)N1CCCC(Nc2nc(N3CCOCC3)ncc2-c2cnc3[nH]ccc3n2)C1 +CCOC(=O)NC(Cc1ccccc1)C(O)CN1CC(C)Cc2ccccc2S1(=O)=O +CC1CNC(=O)c2cc(-c3cccc4ccc(Cl)nc34)[nH]c21 +COc1cc(-n2cnc3cc(-c4ccccc4Cl)sc3c2=O)ccc1OCCN1CCCC1 +CC(C)CCNc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CN(CCCN1CCC2(CC1)OCc1ccccc12)C(=O)C(c1ccccc1)c1ccc(F)c(F)c1 +C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(CN3OCCC3=O)c(F)c2F)c(F)c1 +O=C1Cn2c(Cl)cnc(c2=O)NC(Cc2ccccc2)CNCCCCCOc2ccc(Cl)cc2CN1 +CN1C2CCC1C(C(=O)C(F)(F)F)C(c1ccc(Cl)cc1)C2 +COCCOc1cnc2c(c1)CN(CCn1ncc3c1nc(N)n1nc(-c4ccco4)nc31)CC2 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+COc1ccc2c3c1OC1c4[nH]c5ccccc5c4CC4(O)C(C2)N(CC2CC2)CCC314 +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(NC2CCS(=O)(=O)CC2)nc1OC1CCC1 +Cc1nc(-c2c(F)cc(Cl)cc2-c2cnc(C(C)NC(=O)C3(NC(=O)c4ccnnc4)COC3)c(F)c2)no1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1-n1cc(-c2cncc(N3CCC3)c2)nn1 +CCNC(=O)NC(=O)C1CCCN1C(=O)C(CC1CCCC1)CN(O)C=O +Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CC(=O)NCc1cnc(N)cn1 +CCCCCC=CCC=CC=CC=CC(Sc1ccc2c(=O)cc(C(=O)O)oc2c1)C(O)CCCC(=O)O +CCOc1cc(=O)n(C)cc1-c1cc(NS(=O)(=O)CC)ccc1Oc1ccc(Cl)cc1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)Nc2ccccc2Cl)cc1 +COc1ccc(NC(=O)Nc2ccc(-c3ncnc4[nH]cc(C)c34)cc2)cc1 +CN(C)C(=O)c1ccccc1CCC(SCCC(=O)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2cccnc2)C1 +CN(C)CC=CC(=O)Nc1ccc(C(=O)Nc2cccc(Nc3nccc(-c4cccnc4)n3)c2)cc1 +CC(C)CC(NC(=S)NCc1ccccc1)C(=O)NC1CCOC1O +O=C1C2CCCN2C(=O)N1CCCCNCCOc1cccc(C(F)(F)F)c1 +CC1(C)C=CC(=O)C2(C)OOC3CC12CCC3(O)CO +Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(Cc3n[nH]c(C)n3)C2=O)c1 +O=C(NCC1CCC(CNC(=O)NS(=O)(=O)c2cccc(Cl)c2)CC1)NS(=O)(=O)c1cccc(Cl)c1 +CC(C)n1c(=O)c(C(=O)NCCCN2CCCCC2)c(O)c2ccsc21 +O=C(C1CCCCN1C(=O)COc1ccccc1)N1Cc2ccc(C3CCOCC3)cc2C1 +O=C(NCC1COC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(NC1CC1)c1cnn2ccc(N3CCCC3c3cc(F)cc(OCCN4CCOCC4)c3)nc12 +CC(=O)c1ccc(OCCCN2CCC(NC(=O)c3csc(-c4cccnc4)n3)C2)cc1 +N#CC1(NC(=O)C2CC(S(=O)(=O)c3ccccc3)CC2C(=O)Nc2ccc(F)cc2)CC1 +CN1C(=O)CCC1c1cc2[nH]c(-c3cnccn3)cc2cc1Oc1ccc(S(C)(=O)=O)nc1 +CCc1nccn1CCC(C(N)=O)(c1ccccc1)c1ccccc1 +Cc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1cncs1 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1cccc2c1ccn2C)C(C)C +N#Cc1cnn2c3cc(nc12)N1CCC(C1)OCC=CCOc1cc(cc2c1NC(=O)CC2)N3 +COc1ccc(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cc1 +CC(C)(O)C#Cc1ccc2c(c1)c1cc(Cl)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 +Fc1ccc(C(c2cc3ccccc3o2)n2cncn2)cc1 +COCCNc1nc(-c2ccc(OC)c(OC)c2)cc2ncn(C)c(=O)c12 +O=C(CC1CCN(C(=O)Cn2cncn2)CC1)N1CCC(C2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c32)CC1 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+COc1cc(C(F)(F)F)cc(C2OC(=O)N(C(=O)NCc3cncc4ccccc34)C2CO)n1 +Cn1cc(-c2cc(C(=O)N3CC(O)C3)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +CC(Cc1ccc2[nH]c(C(=O)NCc3nccs3)cc2c1)NCC(O)c1ccc(O)c(CO)c1 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCCO3)n2CCC1CCN(C=O)CC1 +COc1cc2c(c(OC)c1OC)-c1cc3ccn(C)c3cc1C(=O)CC2 +COc1ccc(-c2cc(C(=O)O)nn2-c2cccc(Br)c2)cc1 +O=C(c1ccc(-c2ccc(OCCCN3CCC(O)C3)cc2)cc1)N1CCCC1 +O=C(Nc1ccc(F)c(-c2nc3ncccc3o2)c1)c1ccco1 +COC(C(=O)NC(CCN(C)C)c1ccc2ccccc2c1)c1ccccc1 +CCOC(=O)c1ncn2c1CN=C(c1cccc([N+](=O)[O-])c1)c1cc(Cl)ccc1-2 +O=C(c1ccc(Cl)cc1Cl)C1(n2cncn2)Oc2ccccc2C1O +CCCn1c(=O)c2[nH]c(C3C4CC5OC(=O)C3C5C4)nc2n(CCC)c1=O +Oc1ccc(Cl)c(Nc2cc(C(F)(F)F)nc(-c3cnccn3)n2)c1 +Cn1cc(C2=C(c3nn(CCCN4CCOCC4)c4ncccc34)C(=O)NC2=O)c2ccccc21 +CC1(C)Oc2ccc(C(F)(F)F)cc2C(n2ccccc2=O)C1O +[O-][n+]1nc(CCCN2CCCCC2)[n+]([O-])c2ccccc21 +O=C(Nc1ccc(Nc2ncnc3sccc23)cc1)Nc1cccc(Br)c1 +CCOC(=O)CCc1ccc(-c2ccc(CCN3CCCC3C)cc2)cc1 +CCCCCNC(CNC(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1 +CC#CCn1c(N2CCCC(N)C2)nc2ccn(Cc3cccc4ccccc34)c(=O)c21 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+CCCC1(CCc2ccccc2)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3ccc(F)cc3)c2)=C(O)O1 +O=C(O)c1ccnc(-c2cc(C(=O)NCCc3ccccc3)ccn2)c1 +NC(=O)c1ccc2[nH]c(-c3ccc(C(=O)c4ccc5ccccc5c4)cc3)nc2c1 +O=c1cc(C(F)(F)F)c2cc3c(cc2[nH]1)OCC(c1ccccc1)N3CC(F)(F)F +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccoc3)n(CC(=O)N3CCN(CCO)CC3)c2c1 +Cc1cc(C)cc(C(=O)c2c(OCC(=O)Nc3ccc(S(N)(=O)=O)cc3C)ccc3ccccc23)c1 +O=C(NNc1nc(OCCc2c[nH]c3cc(Br)ccc23)nc2c1ncn2C1OC(CO)C(O)C1O)c1ccco1 +Cc1nc2cccc(-c3cc4c([nH]3)C3(CCOCC3)NC4=O)c2nc1NC(C)(C)C +Cc1nc(N)nc(-c2cc(CN3CCN(S(C)(=O)=O)CC3)cnc2Nc2cnc3c(c2)ncn3C)n1 +CC1CN(Cc2ccc(-c3ccc(F)c(Cl)c3)nc2)C(=O)O1 +CCc1ccccc1N(CC(=O)NCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(C)cc1 +COc1ccc(CCOC(=O)C2=C(c3ccccc3)CCN(C)C2)cc1 +CC1(C)NCC(c2ccc(Cl)c(Cl)c2)c2ccc(-c3ccc(N)nn3)cc21 +Cc1ccc(NC(=O)C2=C(c3ccc(C)cc3)CC(c3ccc(OCCC(F)(F)F)cc3)(C(F)(F)F)NC2=O)cc1 +CCCc1ccc(NC(=O)c2ccccc2NC(=O)Nc2ccccc2[N+](=O)[O-])cc1 +CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2OC)CC1 +COc1ccc(P2(=S)Oc3ccccc3-c3ccccc3O2)cc1 +COc1cc(Cl)cc(COc2cccc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)c2)c1 +CCCC(=O)c1cnc2c(OC)cccc2c1Nc1ccc(O)cc1 +CC(C)COc1ncnc2[nH]cc(C=CC(=O)NCC3CC3)c12 +COc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)cc1F +COc1cccc(NC(=O)CCCNC(=O)C(C)c2ccc(CC(C)C)cc2)c1 +O=c1[nH]c(-c2ccn(CC3CNCCOC3c3ccc(Cl)c(F)c3)c(=O)c2)no1 +COc1ccc(Cl)c(OC)c1C1CC(O)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +COc1cn(C(CC(C)(C)C)C(=O)Nc2ccc(C(=O)O)cc2)c(=O)cc1-c1cc(Cl)ccc1C#N +CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)c2ccccc21 +Cc1cccc(-c2nc3c(=O)n(Cc4ccccc4)nc(C)c3c3cc(-c4ccccc4)nn23)c1 +CN1CCC(NC(=O)c2cc(C#N)ccc2C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C)C1 +COCCCn1c(C)nc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc21 +O=C(OCC#CCSc1nnc(-c2cccc3ccccc23)o1)c1cccnc1F +CCCc1c(OCC(O)CN2CCN(Cc3ccc(Cl)cc3)CC2)ccc2c(O)c([N+](=O)[O-])c(=O)oc12 +COc1cc(N2CCN(C(C)C)CC2)ccc1Nc1nc(Nc2cc(F)c(F)cc2C(N)=O)c2cc[nH]c2n1 +CC(=O)Nc1cccc(C2CCN(Cc3ccc(C(=O)c4nc5ccccc5n4-c4ccc(F)cc4)cc3F)CC2)c1 +COc1cc(C(=O)O)ccc1OCCCCOc1ccc(C(=O)CC(C)C)c(O)c1C +O=S(=O)(c1ccccc1)c1nnn2c1nc(NC1CCCCC1)c1sccc12 +Fc1ccc(Cl)cc1-c1cc(Nc2ccnc3cn(CC4CCNCC4)nc23)ccn1 +Cc1ccc(C(=O)N2CCCCC2)cc1S(=O)(=O)N1CCCCC1 +COc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccccc3)nc1-2 +c1ccc2c(NCCCCCCNc3c4c(nc5ccccc35)CCCCC4)c3c(nc2c1)CCCCC3 +CCCN(CCC)c1c(C)nc(-c2c(C)cc(C)cc2OCCN2CCOCC2)c2ccccc12 +O=C(NC(CCCCCCSSc1ccccn1)C(=O)Nc1nc(-c2ccccc2)cs1)OCc1ccccc1 +COC(=O)c1c[nH]c2cc(CN3CCN(c4ccc(F)cc4)CC3)c(C)cc2c1=O +NS(=O)(=O)c1ccc(CNC(=O)Cc2ccccc2)cc1 +Cc1c[nH]c2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCCCC3)c12 +O=C(O)c1cccc(S(=O)(=O)N2CCc3cc(Br)ccc3C2)c1 +CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(-n2nccn2)cc1)C(=O)O +COc1ccc2cc(-c3nn(CC4CCNCC4)c4ncnc(N)c34)ccc2c1 +N#CCOc1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)C(=O)O)cc1 +CCC(CO)Nc1nc(SCc2ccccc2)nc2[nH]c(=O)sc12 +Cc1cc(SCc2cc(-c3ccc(C(F)(F)F)cc3)cc(-c3ccc(C(F)(F)F)cc3)c2)ccc1OCC(=O)O +CN(C)CCC(Oc1ccc([N+](=O)[O-])cc1)c1ccc(OCCCN2CCCCC2)cc1 +COC(=O)c1c(O)cccc1OCCCCNC(C)CCc1ccc(N(C(=O)C(=O)O)c2ccccc2C(=O)O)c2ccccc12 +COc1ccc(C2(CNC(=O)c3cccc(C)c3C)CCCC2)cc1 +Nc1ccc2ncnc(Nc3cccc(C(F)(F)F)c3)c2c1 +O=C(CN1CCSCC(NC(=O)c2ccccc2)C1=O)NC1CC(=O)OC1O +N#Cc1ccc(NC2CNC(C(=O)N3CCSC3)C2)cc1 +COc1ccc(CN2CCc3sc(C=C4C(=O)N5C(C(=O)O)=CSC45)cc3C2)cc1 +Cn1cc(-c2cc(NS(C)(=O)=O)cc(F)c2Oc2ccccc2)c2cc[nH]c2c1=O +Cc1ccc(-n2nc3c(=O)n(C)c4ccccc4n3c2=O)cc1 +Cc1cc2cc(C#N)ccc2c(C)c1Nc1nc(Cl)nc(Nc2ccc(C#N)cc2)n1 +COC(=O)C1C2CC3CCC1N3CC2=Cc1ccc(C)s1 +CCNC(=O)c1ccc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4cccc(F)c4OC)cc32)cc1C +CC1CCCN(S(=O)(=O)c2ccc(N3CCCC3=O)cc2)C1 +CC(C)n1cc(C(=O)c2cc(NC(=O)Cc3cnn(C4CC4)c3C(F)(F)F)ccn2)c2cnccc21 +c1ccc([Si]2(c3ccccc3)CCC(N3CCN(c4ccccn4)CC3)C2)cc1 +COc1ccccc1CC(=O)N1CCC2(CC1)CN(C(=O)Nc1ccc(OC(F)(F)F)cc1)CCO2 +CS(=O)(=O)c1ccc(-n2cc(COc3ccc(Cl)cc3)nc2-c2ccc(Cl)cc2)cc1 +Cc1cccc(C(=O)Nc2ccc(C(=O)N3CCC4(C=CCCC4)Cc4ccccc43)cc2)c1 +Cc1cc(-c2ccc(NC(=O)C(C)c3cccc(-c4ccc(NC(C)C)nc4)c3)cc2)ccn1 +Cn1nc(C(C)(C)C)c(Cl)c1-c1nc2cc(-c3ccccc3C(F)(F)F)nc(N3CCCC3)c2[nH]1 +CCCc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1C +Cc1nc2c(O)cccn2c(=O)c1CCN1CCN(c2cccc3sccc23)CC1 +c1ccc(Oc2ccc3n[nH]c(-c4nc5cc(N6CCC(N7CCCCC7)CC6)ccc5[nH]4)c3c2)cc1 +O=C1c2cccc3nc(-c4ccccc4Cl)n(c23)CCN1C1CN2CCC1CC2 +Nc1ccc2c(c1)C(=O)c1ccc(Nc3ccccc3F)cc1OC2 +CC1CC(=O)N(CCN2CCN(c3cccc4c3OCCO4)CC2)C1=O +COc1ccc(Cc2cc(C3OC(CO)(CO)C(O)C(O)C3O)ccc2Cl)cc1 +COc1ccc(CCC2=NN(CCCCN)C(=O)N(Cc3ccc(-c4ccccc4)cc3)c3ccccc32)cc1 +CC(C)CN1C(=O)CSC1c1ccncc1-c1ccc(Br)cc1 +CC(C)(O)C1CCC(Nc2ccn3ncc(-c4cccc(Cl)c4)c3n2)CC1 +CC(C)C(C)NC(=O)c1noc(-c2ccc(C(F)(F)F)cc2)c1CO +CCN(CC)C(=O)c1ccc(-c2ccc(OCCCN3C(C)CCC3C)cc2)cc1 +CCN(CC)Cc1ccc(C(c2cccc(Cl)c2)n2ccnc2)cc1 +CN1CCN(c2ccc(-c3ccc4c5[nH]ncc5c(=O)n(CC(F)(F)F)c4c3)cc2)CC1 +O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1cc([N+](=O)[O-])ccc1Cl +CC(C)(O)CCNC(=O)c1cnc(-n2ccc3cc(Cl)cnc32)cc1NC1CCOCC1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(C2CCN(C)CC2)n1 +COc1cccc(CN2CCC(N3CC(c4ccccc4)(c4ccccc4)NC3=O)CC2)c1 +CN(C)c1cccc2c(S(=O)(=O)Nc3cnc(Br)cn3)cccc12 +Cn1cnc(-c2cc3nccc(Oc4ccc(N5CCCc6c(cnn6-c6ccccc6)C5=O)cc4F)c3s2)c1 +Cc1onc(-c2ccccc2)c1CNCC(O)c1ccc(O)c2[nH]c(=O)sc12 +COC(OC)C1=C(C(=O)OCC=Cc2ccccc2)C(c2ccc(Cl)c(Cl)c2)C(C(=O)O)=CN1 +Nc1ccc2c(c1)C(=O)C(=O)c1cc(N)ccc1-2 +Cn1cnc(S(=O)(=O)N2CC3C(C2)C3(CNC(=O)c2cc(Cl)cc(Cl)c2)CC2CC2)c1 +COc1ccc(C2CC(=O)C3=C(C2)NC(C)=C(C(=O)OC(C)C)C3c2ccc(F)cc2)cc1OC +COC1C(OC(=O)NN2CCOCC2)CCC2(CO2)C1C1(C)OC1CC=C(C)C +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NCCF)c12 +Cn1c(=O)c2c(nc(N3CCCC(N)C3)n2Cc2ccccc2F)c2cc(C(=O)O)ccc21 +O=C(C(=O)N1CCCC(C(=O)NCc2ccccc2)C1)c1c[nH]c2ccccc12 +NC(=O)c1ccc(-c2ccc3c(C=O)c(O)ccc3c2)cc1 +N#CC(CC(N)=O)NC(=O)C1CCCN1C(=O)OCc1ccc(-c2ccc(Cl)cc2)cc1 +Fc1cc2[nH]ncc2cc1-c1ccccc1C(F)(F)F +N#Cc1cccc(-c2nc(C3CCC(C(=O)O)CC3)cc3cccnc23)c1 +Nc1ccc(-c2ccccc2)c[n+]1CCCc1ccc(CCC[n+]2cc(-c3ccccc3)ccc2N)cc1 +N#Cc1ccc(-c2ccc(CNCCCNc3ccnc4cc(Cl)ccc34)s2)cc1 +CC(NC(=O)c1ccco1)C(=O)N1CCCN(CCCOc2ccc(-c3noc(CC(C)(C)C)n3)c(F)c2)CC1 +NC1CC(N)C(OC2OC(CNC(=O)c3ccc4ccc5cccc6ccc3c4c56)C(O)C(O)C2N)C(O)C1O +c1ccc2cc(-c3ccc4[nH]c(-c5ccc6[nH]c(-c7ccc8[nH]cnc8c7)nc6c5)nc4c3)ccc2c1 +CCCCCCOC(=O)C(C)NP(=O)(OCC1OC(n2ccc(N)nc2=O)C(F)(F)C1O)Oc1ccccc1 +CCOC(O)=C1C(COCCN(C)C(=NC)NC#N)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +CN(C)CC(c1cccc(C(F)(F)F)c1)C1(O)CCCCC1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN2CCN(C)C2=O)c1C +O=C(NCC#CCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc2c(c1)Cc1ccccc1-2 +COC1C(CO)OC2C(C1O)n1c3ccc(CO)cc3c3c4c(c5c6cc(CO)ccc6n2c5c31)C(=O)NC4=O +NC(=O)c1cnc(NC2CCNC2)c2cc(-c3ccc(Cl)cc3)sc12 +Cn1ccnc1-c1cccc(C2=Nc3ccc(C#Cc4ccccc4)cc3NC(=O)C2)c1 +N#Cc1cc(S(=O)(=O)c2nc(-c3cnn4ccc(Br)cc34)cs2)ccc1NCCN1CCOCC1 +Cc1cc(-c2nc(-c3ccc4cc(CCN5CCCC5C)ccc4n3)cs2)no1 +CC(C)(C)C(NC(=O)C(CC1CCc2ccccc2C1)C(O)C(=O)NO)C(N)=O +CCCCS(=O)(=O)NC(CNC(=O)c1cc2cc(CCC3CCNCC3)sc2s1)C(=O)O +CSc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(C)=O)cccc2-3)cc1 +COc1cc(Oc2cnc(N)nc2N)c(C(C)C)cc1OC +CC1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 +Cc1ccc(S(=O)(=O)n2c(C)c(CC(=O)O)c3cccnc32)cc1 +O=S(=O)(NCc1ccccc1Cl)c1ccc2c(c1)CCNCC2 +CSc1ccc(NC(=O)Cn2c(-c3cscn3)nc3ccccc32)cc1 +CCCCNc1cc(NC(C)C(Cc2ccc(Cl)cc2)c2cccc(Br)c2)nc(C)n1 +CC(=NNc1nc(-c2ccc(F)cc2)cs1)c1ccncc1 +O=C(OC1C[N+]2(CCCOc3ccccc3)CCC1CC2)C(c1cccs1)c1cccs1 +Cn1cc(-c2cc3cnc(Nc4ccc(-c5cncn5C)cc4Cl)cc3n2C(=O)OC(C)(C)C)cn1 +CC(=O)c1cccc(NC(=O)NCCCC2CC(Cc3ccccc3)CCN2)c1 +CCCCC(=O)N(Cc1cccc(OC)c1)c1cccc(-c2nnn[nH]2)c1 +NC(=O)n1cc(NC(=O)N2CCSC2C(=O)NCc2cccc(Cl)c2F)c2cc(OCCO)ccc21 +COC(=O)Nc1ccc2c(c1)oc1cc(S(=O)(=O)NC(C(=O)O)C(C)C)ccc12 +CCNC(=O)Nc1cccc(CCCCOCCCCCCNCC(O)c2ccc(O)c(CO)c2)c1 +COc1ccc(OC)c(C=CS(=O)(=O)Cc2ccc(OC)c(N)c2)c1 +Cc1ccnc(NC(c2ccncc2)c2ccc3cccnc3c2O)c1 +CCC1CCC(n2cnc(CC(CCCN)C(=O)O)c2)CC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC(C)(C)F)cn3)C2)cc1 +CCC1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=Nc1ccc(Cl)cc1 +OCC1CCN(Cc2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +Cc1ccc(-n2cccn2)cc1CC1COCCN1C(=O)c1cccc(C)c1-n1nccn1 +Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(C#N)c2ccc(Cl)cc2F)CC1 +COC1=CC(=O)C(O)=C(CC2(C)CCC3(C)C(C)=CCCC3C2C)C1=O 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+O=C1OC2(CCN(c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)CC2)CC1Cc1ccc(F)cc1 +Cn1cnnc1S(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(CC2CC2)CC1 +COc1cnc(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)cc1OC +CCCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)c2cc1OC +CCOC(=O)c1c(OC2CC(C)(C)CC(C)(C)C2)c(CC)c(C)[nH]c1=O +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1CC2CCC1(C)C2(C)C)C(=O)NCCc1ccccc1 +CC1CN(C)CCC1c1cc2c(cc1-c1ccc3c(c1)OCCO3)OCC1=NNC(=O)C(C)N12 +Clc1ccc(-c2ccc(-c3nccn3-c3ccc(C4C=CCNC4)cc3)o2)cc1 +O=C(Nc1cc2ccccc2cn1)N1CCN(c2ccccc2C(F)(F)F)CC1 +O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O)Nc1cccc(Cl)c1Cl +Cc1ccc(NC(=O)N2CCOc3ccc(C=O)nc32)nc1 +CCCNC(=O)c1cccc(-c2cc(C=O)c(O)c([N+](=O)[O-])c2)c1 +Nc1ncc(C2CCOCC2)nc1-c1ccc(C(=O)NCc2ccccc2)c(F)c1 +CSCC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C +Clc1ccc(Nc2nnc(SCc3ccccc3)[nH]2)cc1 +COc1cc(Nc2nc(NC3CCCCCC3N)n3ccnc3c2C(N)=O)cc(OC)c1 +O=C(NCC1CC(F)CN1)c1ccc(-c2cnc3ccc(NCCCF)nn23)cc1F +CC(O)C(O)c1cnc(N2CCN(C(=O)Nc3nc4ccc(F)cc4s3)CC2C)c(F)c1 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+Cc1c(C)c2ccc(OCCCN(C)Cc3ccccc3)cc2oc1=O +CC(C)(Cc1ccc(NC(=O)CCCNC(=N)N)cc1)NCC(O)c1ccc(O)c2c1OCC(=O)N2 +CC(C)(C)c1ccc(Cn2c(=N)n(CC(=O)c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)c3ccccc32)cc1 +Nc1ncnc2c1ncn2C1OC(CNS(=O)(=O)NC(=O)c2ccccc2O)C(O)C1O +COC(C)c1cn(C2=NCC(=O)N3CCc4c(cccc4C4CC4)C3=C2)cn1 +O=C(NCC#Cc1ccc2ncnc(-c3ccccc3)c2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +O=C(c1ccc(-c2oc3ncnc(NCC4CCCO4)c3c2-c2ccccc2)cc1)N1CCOCC1 +COC(=O)c1ccccc1C1CCC(CNc2nccc(C)c2NC(=O)CC#N)CC1 +O=C(NS(=O)(=O)C1CC1)c1cc(C2CC2)c(OCC2CCC3CC3C2)cc1F +CSc1nc2c(c(-c3ccc(N(Cc4cccnc4)C(=O)c4ccc(O)cc4O)cc3)n1)CCC2 +O=C(CCCCCNC(=O)NC1CCCCC1)NC(Cc1ccccc1)C(=O)O +O=C(O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(C4CC4)cc3)nc2)C1=O +O=C(Nc1cccc(Cc2nnc(O)c3ccccc23)c1)C(F)(F)F +COc1ccc(C(=O)N2CCN(C(=NC#N)Nc3ccccc3C)CC2c2ccccc2)cc1OC +Cn1cc(-c2cc(-c3cccc(F)c3)ccc2OCC2CC2)c2cc[nH]c2c1=O +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2ccccc2)c(Br)c1 +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)N)c1 +CCOc1ccc2cc(-c3nn(C4CCCCC4)c(N)c3C(N)=O)cnc2c1 +CSC(=S)N1CC2(CCCCC2)COC1=Nc1ccc(C#N)c2ccccc12 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1cccc(F)c1)CC2 +C[N+]1(CCCC(=O)Nc2ccc3c(c2)C(=O)c2cccc4ccnc-3c24)CCCC1 +NC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4ccccc4)c(F)cc3F)cc1CC2 +Cc1ccc(C)c(C(=O)NC(C)C(=O)N2CCN(CCCOc3ccc(-c4noc(CC5CCCC5)n4)c(F)c3)CC2)c1 +CN1C(=N)NC(CC2CC2)(c2cccc(-c3cccc(Cl)c3)c2)C1=O +Cc1cc(-c2cc(F)c(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)cc2F)ccn1 +CCN(CC)CCNC(=O)Nc1nc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(C)cc4)c3)cn2n1 +COc1ccc(C=C2c3ccccc3C(=O)c3ccccc32)c(OC)c1O +O=C(Nc1ccc(Cl)cc1)c1cc(F)ccc1NC(=O)c1sc2ccccc2c1Cl +CN(C)c1cccc2c(S(=O)(=O)NCCCNc3ccnc4cc(Cl)ccc34)cccc12 +CCCCCCCCCCOc1ccc(OCC(=O)COc2cccc(OCC(=O)O)c2)cc1 +CN(C)c1ccc(NC(=O)NC2C3CCN(CC3)C2Cc2cccnc2)cc1 +CCOc1cc(COc2ccc3c(c2)NCCN(C(C)C(=O)NO)S3(=O)=O)cc(OCC)c1 +Cc1c(C(=O)CS(=O)(=O)c2ccccc2)sc2ccccc12 +COc1ccc(-c2nc(COc3ccc(OCC(=O)O)c(C)c3)oc2-c2ccc(OC(F)(F)F)cc2)cn1 +CC(C)OC(=O)N1CCC(Oc2ncnc(N3CCc4cc(S(C)(=O)=O)ccc43)n2)CC1 +O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CCC(C(=O)Nc1ccc(-c2ccccc2)cn1)n1nnc(-c2ccncc2)c1-c1ccccc1 +OCC1OC(n2ccc3c(-c4cccs4)ncnc32)C(O)C1O +O=C(Nc1cccc(N2CCN(CCCCNS(=O)(=O)CC3CCCCC3)CC2)c1)C1CC1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCCC(C)(C)NS(C)(=O)=O +CN1CCCC1c1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1 +Cc1nc(NCc2cccc(OC(F)(F)F)c2)nc(-n2ccnc2C)c1[N+](=O)[O-] +CCCCCCCCC(O)C=Cc1cccc(CC(O)c2cccc(C(=O)O)c2)n1 +CN(Cc1cccc(O)c1)C(=O)c1ccc(-c2cccc(N(C)C)c2)s1 +CC(=O)Nc1ccc2nc(Nc3c(C)cccc3Cl)c3cncn3c2c1 +COc1ccc(C2CC2COc2nc(N)nc(NCc3nnc(C)s3)c2F)nc1 +CCC(C)C(CC(=O)O)NC(=O)C(CC)(CC)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 +C=C1CC2C(CCC3(C)C(c4cncc(F)c4)=CCC23)C2(C)C=CC(=O)C=C12 +COc1cc2c(cc1NS(=O)(=O)c1ccccc1)cc(C)c(=O)n2C +CCOc1ccc(Cl)cc1-c1cc(Nc2ccc(Cl)cc2)nc(N)n1 +O=C(NC1CCC1)C1SC(n2cnc3c(NCc4cccc(I)c4)ncnc32)C(O)C1O +N#Cc1ccc(-c2n[nH]c3cc(OC(F)(F)F)ccc23)cc1 +Cc1ccc(C)c(S(=O)(=O)Nc2onc(C)c2Br)c1 +NC(CC(=O)N1CCSC1C(=O)NCc1ccc2c(c1)OCC(C(=O)O)O2)Cc1cc(F)c(F)cc1F +O=C1N(c2ccc3c(c2)OC(F)(F)O3)CCN1c1cnccc1C1CC1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3cccc(C(F)(F)F)c3)cc2)C(=O)C(C)C)c1 +Cc1ccccc1OC1CCN(c2nc(Cl)cn(C)c2=O)CC1 +OC1CCN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)CC1 +COc1ccc(C(=O)C2CCN(CC(=O)N(Cc3nc4c(c(=O)[nH]3)COCC4)CC(F)F)CC2)cc1 +c1ccc(CCCNC2CCCCN(CCOC(c3ccccc3)c3ccccc3)C2)cc1 +N#Cc1cccc(-c2cnc(C(=O)CCc3ccc(-c4ccccc4)cc3)o2)n1 +Cc1cc(Nc2ccccn2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +O=C(N1CCN(Cc2ccc3ccccc3c2)CC1)n1cc(I)cn1 +COCCN1CC2C(C1)C2c1cc(-c2cnc(N)c(OC(F)F)c2)nc(C2CC2)n1 +CCCCCn1nc(C(=O)NC(C(N)=O)C(C)C)c2ccccc21 +N=C(N)c1cccc(CN2CCC(NS(=O)(=O)c3ccc(-c4cccnc4)s3)C2=O)c1 +CS(=O)(=O)c1ccc(Oc2cc(OC3CCOC3)cc(C(=O)Nc3nccs3)c2)cc1 +CC1CCCCC1Oc1nc(N)c2c(=O)ccn(CC3CC(O)C(O)C3)c2n1 +Cc1ccc(-c2csc(=N)n2CC(=O)N2CCN(C)CC2)cc1 +CCOc1nc2c(n1Cc1ccc(OC)c(Cl)c1)C(=O)N(CC)C1=NC3CCCC3N12 +COc1cc(-c2ccc3c(c2)Nc2ccccc2NC3=O)ccc1[N+](=O)[O-] +CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)nn1-c1ccccc1 +CN(CC(CCN1CCC2(CCc3ccccc32)CC1)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 +CC(C)C(CO)NCc1nc(-c2cccc(S(=O)(=O)N3CCCCC3)c2)ccc1F +CC(C)COc1ccc(-c2n[nH]c(-c3ccncc3)n2)cc1C#N +Cc1nc(C)c(COc2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)o1 +Nc1ncnc2c1c1c(Cl)cccc1n2C1OC(CO)C(O)C1O +Cc1ccc(COc2ccc3nc(C4CCCCC4C(=O)O)n(Cc4ccc(OC(F)(F)F)c(Cl)c4)c3c2)nc1 +O=C(NC1CC1)c1ccc(Nc2nc(Nc3ccc(O)cc3)ncc2F)cc1 +Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccccc1S(=O)(=O)N1CCCCC1 +CC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCC2C(O)c1cccc2ccccc12 +O=C(Nc1cccc(-c2ccn[nH]2)c1)C(Cc1ccccc1)NCc1cscn1 +CC12CCC(Cc3ccccc3)C(=O)N1C(C(=O)NC(CCCN=C(N)N)C(=O)c1nccs1)CS2 +CCCC1C(C#N)=C(N)Oc2[nH]nc(C(C)(C)C)c21 +Nc1cccc(Nc2nc(NCCO)nc(NCCc3ccc(Nc4nc(NCCO)nc(Nc5ccc(Cl)cc5)n4)cc3)n2)c1 +O=C(c1cc(=O)c2cc(O)ccc2[nH]1)N1CCC(Cc2ccccc2)CC1 +CC(C)N(c1ccc(Nc2ncc3cnn(C4CCCCCC4)c3n2)cc1)S(C)(=O)=O +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)cc(-c3cccc(C#N)c3)c2C)cc1 +N#Cc1ccc(Oc2ccnc3cc(-c4cnn(C5CCNCC5)c4)ccc23)cc1 +CC(c1ccc(-c2ccc(C(=O)O)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +CN1CCC(Nc2ccc3nnc(-c4cccc(C(F)(F)F)c4)n3n2)CC1 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+Cc1cc(Nc2cc(-n3cc(C)cn3)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1 +O=C1CC(c2ccc(CC(NS(=O)(=O)c3c(F)cccc3F)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 +O=c1[nH]nc(-c2cc(Br)c(O)cc2O)n1-c1ccccc1F +OC(c1ccc(Cl)cc1)(c1cccnc1)c1ccc(C(F)(F)F)cc1F +CN1CCC(Oc2ccc(Nc3cc(-n4cnc5ccccc54)ncn3)nc2)CC1 +CCc1c(C)nc(SCC(=O)c2cccs2)c(C#N)c1C +O=C1NCc2cc(Oc3ccc(Nc4ncnc5ccn(CCO)c45)cc3Cl)ccc21 +CCOC(=O)c1cn(Cc2ccccc2F)c2cc(-c3ccc(NC(C)=O)cc3)c(CN(C)Cc3ccccc3)n2c1=O +O=C(NCC(CC1CC1)c1cnc(C(F)(F)F)nc1)c1ccccc1Cl +O=C(Nc1cc2ccccc2s1)c1nc(-c2cccs2)nc(O)c1O +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2ccccc2Cl)s1 +CCc1cc(OCc2ccc(-c3ccc(Cl)cc3-c3nn[nH]n3)cc2)c2c(n1)CCCC2 +CCC1(c2cccc(Oc3cc(Cn4ccnc4)ccc3C#N)c2)CCCCNC1 +CCOC(=O)c1c(-c2ccccc2)c(-c2ccccc2)n(CCC2CC(O)CC(=O)O2)c1C(C)C +COc1ccc(CC(S)C(=O)NCC(=O)N2C(C(=O)O)CCC2c2ccccc2OC)cc1 +COc1cc2cc(CO)c(CO)c(-c3ccnc(-n4ccc(=O)c5ccccc54)c3)c2cc1OC +CCNC(=O)c1ccc(Oc2ccccc2)c(-c2[nH]c(C)c3c2CCCC3=O)c1 +COCC(NC(=O)Cc1cccc(OCc2ccccc2)c1)C(=O)NC(CCc1ccccc1)C(=O)NCc1ccc(C)cc1 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+COc1ccc(Nc2ncc(CNCCO)cc2-c2nc(C)nc(N)n2)cn1 +N#CNc1ccc(Nc2ncc(C(F)(F)F)c(Nc3ccc4[nH]cnc4c3)n2)cc1NC#N +COc1ccc(C(=O)Nc2cccc(C(CCCO)Nc3ncnc4c(C(N)=O)cccc34)c2)cc1 +CN1CCN(CCNC(=O)c2ccc3c(c2)C(=O)c2ccc(Nc4ccc(F)cc4F)cc2CC3)CC1 +Brc1ccc(Br)c(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)c1 +Cc1cc(C(N)=O)ccc1-n1nc(C(F)(F)F)c2c(-n3cnc(-c4cccnc4)c3)ccnc21 +CCC(=O)N(Cc1ccc(S(C)(=O)=O)cc1)c1cccc(-c2nnn[nH]2)c1 +CCCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccccc3)C2)C1c1ccc(Cl)cc1Cl +Cc1c(C(=O)Nc2cccc(S(F)(F)(F)(F)F)c2)nn(-c2cc(Cl)cc(Cl)c2)c1-c1ccc(Cl)cc1 +CC(C)N1CCN(CCN2CCN(c3cccc(Cl)c3F)C2=O)CC1 +COc1cccc(Oc2ccc(-c3ccc(C(C)NC(C)=O)cc3)cc2)c1 +CN(C)Cc1ccc(NC(=O)c2cccc(CNC(=O)Nc3ccc(C(N)=O)cc3)c2)cc1 +O=C(c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12)N1CC(CO)C1 +CCCCN(CCCC)CCCNC(=O)C(Cc1ccccc1)NC(=O)C1(NC(=O)c2cc3ccccc3s2)CCCCC1 +CN1CCC(n2cc(-c3cnc(N4CCOC(Cn5nc(-c6ccc(F)c(F)c6)ccc5=O)C4)nc3)cn2)CC1 +O=C(Nc1ccc(-c2ccncc2)c(-c2ccccc2F)n1)C1CC1 +CC(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccncc3)c2)s1 +C=CCn1c(SCC(=O)Nc2ccc(S(N)(=O)=O)cc2)nc2ccc(C)cc2c1=O +CC1(C)C(C(=O)NO)N(S(=O)(=O)c2ccc(Br)cc2)CCCS1(=O)=O +O=C1C(=O)c2c(nc3cnccn23)-c2ncccc21 +COC(=O)c1cc(-c2ccc(OC)cc2)c(-c2ccncc2)n(C)c1=O +CCCN(CCC)C(=S)N1CCC(c2cccc(Cl)c2)=N1 +COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1F +COc1ccc(Nc2ncccc2C(=O)NCC(O)CN2CCN(c3ccccc3OC)CC2)cc1 +O=C(Nc1ccc(S(=O)(=O)NC2CCCCC2)c2ccccc12)c1ccccc1 +N#CC(=Cc1cc(O)c(O)c(O)c1)C(N)=C(C#N)C#N +N#Cc1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +CC(=CC(C)C(=O)c1ccc(N(C)C)cc1)CCC(=O)NO +O=C(NN1CCOCC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1Cc1cc(C3CC3)ccc1-2 +CCONC(=O)c1cn(C)c(=O)c(F)c1Nc1ccc(Br)cc1F +CCCN(CCC)C(=O)c1cc(C)cc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(CC3CCCCC3)CCN2)c1 +O=C(C1Cc2ccccc2CN1C(=O)CCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCCCC1 +COc1cc(OC)cc(N(CCC2CCN(C(C)C)CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C1c2ccccc2C(=O)c2c(NCCN3CCCCC3)nnc(NCCN3CCCCC3)c21 +NC(Cc1c[nH]c2ccccc12)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O 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+O=C(Cn1nnc(-c2ccccc2C(F)(F)F)c1-c1ccccc1)Nc1ccc(-c2ccccc2)cn1 +C(=C(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1)c1ccccc1 +CCc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3c2ccc(Cl)c3F)ccc1OCCN1C(=O)CCC1=O +Nc1ncc(-c2cc(C3CC4CC(C3)CN(C3COC3)C4)nc(C3CC3)n2)cc1OC(F)F +Cc1cc(-n2ncc(=O)[nH]c2=O)cc(Cl)c1Oc1ccc(O)c(S(=O)(=O)N2CCCCC2)c1 +Cc1ccc(C(=O)Nc2cc(N3CCCN(C)CC3)cc(C(F)(F)F)c2)cc1Nc1ncnc2ccc(N3CCOCC3)nc12 +CCCCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc2c(ccn2-c2ccccc2-c2nnn[nH]2)c1 +COc1ccc(S(=O)(=O)N(Cc2cccnc2)c2c(C)cc(N(C)C)cc2C(=O)NO)cc1 +CCN(CC)CCOc1ccc2c(c1)C1(CCNCC1)c1[nH]c3ccccc3c1C2=O +CCn1nc(Cc2ccccc2)cc1C1CCN(CC2CN(C(C(=O)O)C3CCC3)CC2c2ccccc2)CC1 +CC(C)N1CCN(C(=O)OC2CCN(c3ccc(=O)n(C)n3)CC2)CC1 +O=C(Nc1cccc(C#Cc2ccc3nccn3n2)c1)c1cccc(C(F)(F)F)c1 +CCCCCN=C(N)Cc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +Cc1ccc(Sc2cnc(Nc3cccc(Br)n3)s2)cc1C(=O)N1CCN(C(=O)C(C)N)CC1 +O=C(O)CCNC(=O)c1cccc(C(=O)NCCC2CCNCC2)c1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)c1sc2ncccc2c1-c1ccc(Cl)cc1 +NS(=O)(=O)c1ccc(Nc2ccnc(NS(=O)(=O)C(F)(F)F)n2)cc1 +CC(C)(CCCOc1ccc(C=Cc2ccc(Cl)cc2)cc1)C(=O)O +Nc1ncc(-c2cnn(C3CCC(O)CC3)c2)c2c(-c3cncs3)c(-c3cccc4nnsc34)oc12 +CCN1C(=O)C(=Cc2ccc(-c3ccccc3C(F)(F)F)o2)SC1=S +Nc1nonc1-n1nnc(C(=O)NN=Cc2cc(Br)ccc2O)c1CNc1ccccc1 +COc1cc(S(=O)(=O)c2cccc(C3CCOC3)c2)cc2c3c(oc12)CCNC3 +COc1ccc(C2CC2C(=O)N2CCc3c(F)ccc(-c4cc(CC(=O)O)ccc4OC)c3C2)cc1 +CCN1CCN(c2cc(-c3n[nH]c4ccc(OCCOC)cc34)ncn2)CC1=O +COCCCOc1cc(C(=O)N(CC2CNCC2OCc2cccc(OC)c2)C(C)C)ccc1OC +Cc1cc(C(=O)Nc2cnn(Cc3ccc(Cl)cc3Cl)c2)no1 +Cc1ncc(CN2CC(C)C(c3nc4c(cnn4C4CCOCC4)c(=O)[nH]3)C2)cn1 +Cc1nnnn1-c1ccc2c(c1)C=CS(=O)(=O)O2 +O=C(NC(=S)Nc1cc(C(F)(F)F)ccc1Cl)c1ccccc1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5cccc(F)c5)C4=O)c3)nc2n(CCC)c1=O +Cc1cc(C(=O)O)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21 +Cn1c(C(=O)Nc2ccccc2COc2ccc(CC3CCNC3)cc2)cc2sccc21 +CCOC(=O)c1cn(Cc2ccccc2F)c2nc(-c3ccc(OC)cc3)c(CN(C)Cc3ccccc3)n2c1=O +NC1=NC(c2ccnc(C(F)(F)F)c2)(c2ccc(F)c(-c3cncnc3)c2)c2cccc(F)c21 +COc1cc(-c2cn[nH]c2)ccc1C(=O)NC(CO)C(O)c1ccccc1 +[H]C([H])(F)Oc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(Cl)c(C(C)(C)O)c2)n1 +NC(=O)C(NC1CCC(c2c[nH]c3cccnc23)CC1)C1CCN(C(=O)C=Cc2ccccc2)CC1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(Cc4nc(C)no4)c4ccccc43)CC2)C(C)C)c1 +CN(CC(=O)NN)C(=O)Oc1ccc(Cl)cc1C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCNCCn1c(CC(C)CC(C)(C)C)nc2cc(C=CC(=O)NO)ccc21 +NCCc1cn(C(=O)c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)cn1 +CS(=O)(=O)c1nnc(-c2ccc3[nH]cc(-c4cccc(N5CCOCC5)n4)c3c2)s1 +CC1CN(S(=O)(=O)NCCCCCNc2nc(-c3ccccn3)cs2)CC(C)O1 +CC1(C)OC2=C(C(=O)C(=O)c3ccccc32)C1Nc1ccc(C(=O)C=Cc2ccccc2)cc1 +COc1cc(C(C)n2c(N)nc3cc(C#CCCO)cnc32)ccc1OCc1ccc(C(F)(F)F)nc1 +CC(C)Oc1ccccc1N1CCN(C2CCC(NS(=O)(=O)c3ccc(S(C)(=O)=O)cc3)CC2)CC1 +Cc1ccc(NC(=O)OCc2ccccc2)c(=O)n1CC(=O)NC(CC(=O)O)C(=O)COc1ccccc1 +c1ccc(Oc2ccc(-c3cc(N4CCNCC4)[nH]n3)cc2)cc1 +COc1ccc(-c2nn3c(-c4ccccc4F)nnc3s2)cc1 +C=C(CCC(C)C1CCC2(C)C3CCC4CC(OC(C)=O)CCC45CC35CCC12C)C(C)C +O=C(Cc1ccc(-c2ccc3cccnc3n2)cc1)NCc1ccc(-c2ccc(F)c(C(F)(F)F)c2)cc1 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+COC(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccc(Cl)cc3)ncc12 +O=C(O)c1ccccc1-c1ccc(CN2CCC(CNC(=O)c3c4n(c5ccccc35)CCCO4)CC2)cc1 +CC1c2nnc(-c3nc(C(F)(F)F)ns3)n2CCN1C(=O)c1ccc(F)cc1 +Cc1c(C(=O)c2csc3ccccc23)c2ccccc2n1CCN1CCOCC1 +CN1CCC23c4c5ccc(O)c4OC2c2ncc(-c4ccc(Cl)cc4)cc2CC3(OCc2ccccc2)C1C5 +CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3ccc(C(=O)NC)cc3)sc12 +COc1cnc2c(NCc3nnc4ccc(-c5cnc(C)s5)nn34)ccnc2c1 +CC(C)(CC(=O)N1CCSC1)NCC(=O)N1CC(F)CC1C#N +CNc1ncnc2ccc(C#CCNC(=O)c3cc(OC)nn(Cc4ccc(F)c(F)c4)c3=O)cc12 +C#CCOc1cnc(C(=O)Nc2ccc(F)c(C3(CF)N=C(N)OC4CC43)c2)cn1 +N#Cc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(F)c3)cn2CCN2CCCC2)CC1 +O=C1CCc2c(Oc3ccc4c(c3)CC(NC(=O)c3cc(-c5cnc[nH]5)cc(C(F)(F)F)c3)CC4)ccnc2N1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCN(c3nc(Cl)c(C(F)(F)F)cc3Cl)CC1)C(=O)C2 +COc1cccc(Nc2cncc(-c3cc4c(cnc5cc(OC)c(OC)cc54)c(N)n3)c2)c1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C(C)C)c2cc1OC +COc1ccc(Oc2ccc(C3(N4CCN(CCO)CC4)C(=O)NC(=O)NC3=O)cc2)cc1 +COCCCn1c(CN2C(=O)C(=NOCCC3CCCCC3)c3ccccc32)nc2ccccc21 +CC(C)CC(NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +C=CCN(C)CC=CCOc1ccc(-c2nsc3cc(Br)ccc23)cc1 +CNS(=O)(=O)NC(=O)c1cc(Cl)c(COc2ccc3c(c2)CCC(C)(C)C3)cc1F +COc1cc2c(cc1S(=O)(=O)NC1C3CCC(C3)C1CC=CCCCC(=O)O)oc1ccccc12 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2cc(-c3cccc(C(=O)O)c3)sc2c1 +Nc1ncc(-c2ccccc2Cl)nc1C(=O)Nc1ccccc1 +COc1cc(OCc2cccc(-c3cnc(F)c(C)c3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +N#Cc1c(Cl)nc(SCc2cccc(C(=O)O)c2)nc1-c1ccccc1 +O=C(Nc1ccc(CCc2ccc(O)c(O)c2)cc1)c1c(O)ccc2ccccc12 +Fc1ccc2[nH]cc(C3CCC(N4CCN(c5cccc6ncccc56)CC4)CC3)c2c1 +Oc1nc2ccccc2n1C1CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1 +O=C(O)C(Sc1nc(Cl)cc(Nc2cccc(-c3ccccc3)c2)n1)c1cccc2ccccc12 +Cn1ccc(NC(=O)c2cccc(-n3cc(NC(=O)Nc4ccccc4Cl)cn3)c2)n1 +Cc1nc(NC(=O)N2CC(O)CC2(C)C(N)=O)sc1-c1ccnc(C(C)(C)C)n1 +COc1cccc2oc(-c3cnc4ccc(OCCCS(C)(=N)=O)nn34)cc12 +Nc1nc(C(=O)NCc2ccccc2)c2cccc(F)c2n1 +COC(C)c1ccnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4ccnc(N)c34)cc2)c1 +CCS(=O)(=O)c1ccc2c(c1)nc(C(C)(C)C)n2C1CC1 +CCOc1ccc2cc(-c3nn(C4CCC4)c(N)c3C(N)=O)cnc2c1 +N=C(N)c1ccc(CNC(=O)Cn2c(-c3ccccc3)c(Cl)nc(NCCc3ccc(Cl)cc3)c2=O)cc1 +Cc1ocnc1C(=O)Nc1n[nH]c2c1CN(C(=O)N1CC(C)N(C)CC1C)C2(C)C +CC1CN(CCC2CCN(Cc3ccccc3)CC2)C(=O)N(c2cccc(C(=N)N)c2)C1 +CCOCC1CN(C(=S)SSC(=S)N2CCCOC(COCC)C2)CCCO1 +CSCC(CN(Cc1ccccc1)Cc1c[nH]c2c(=O)[nH]cnc12)C(O)CO +N#Cc1ccc(Nc2nc(N)nc(Oc3ccc4ccccc4c3Cl)n2)cc1 +Cc1cc(OCc2ccccc2)cc(N2C(=O)c3ccccc3C2=O)c1 +O=c1[nH]c(-c2cc(-c3ccc(Cl)c(Cl)c3)ncn2)no1 +COc1ccc(NC2=CC(=O)C(=NO)c3ccccc32)cc1 +CC(C)CS(=O)(=O)N(C)C1CCN2CCc3ccccc3C2C1 +O=C(NCc1ccc(Cl)cc1Cl)C1CCC(=O)N1C1CCC1 +O=C(Nc1ccc(OCc2ccccc2)cc1)Nc1ccc2cnn(CCN3CCCC3)c2c1 +NCCCCC(NC(=O)C(Cc1ccc(-c2cccs2)cc1)NC(=O)OCc1ccccc1)C(N)=O +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCCC1CN(C)CC(C)(C)O1 +CN1CCN(c2ncc3ncnc(Nc4cc(Cl)cc(C(=O)Nc5cc(C(C)(C)C)nn5C)c4)c3n2)CC1 +CN(C(=O)COc1ccc(Cl)c(Cl)c1)C1CCCCC1N1CCCC1 +O=C(CCC1CCN(Cc2ccccc2[N+](=O)[O-])CC1)c1cc2c3c(ccn3C(=O)CC2)c1 +Brc1cccc(Nc2ncnc3cc4c(cc23)OCCSCCO4)c1 +O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2ccc(Cl)cc2)c1 +CCOC(=O)C(C)NP(=O)(OCC1(N=[N+]=[N-])OC(n2ccc(N)nc2=O)C(O)C1O)Oc1ccccc1 +Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)cc1-c1ccc2c(N)noc2c1 +CCCCCn1cc2c(=O)n(C3CCCCC3)nc-2c2ccccc21 +CCC(c1nncn1C)N(Cc1ccccc1Cl)c1ccc(C#N)c(Cl)c1 +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)NCC(=O)O)cc12 +CC(=O)NC1CCc2c(-c3noc(-c4ccc(OC(C)C)c(C#N)c4)n3)cccc21 +Nc1ccccc1-c1nnc(Nc2ccc3c(c2)OCCO3)o1 +O=C(NCc1ccc([S+]([O-])c2cccc(OC(F)(F)F)c2)cn1)c1cc2ccncc2o1 +COc1cc2c(c(OC)c1)C1C3CCCC(C(=O)N1CC2)N3C(=O)C(=O)c1ccc(F)cc1 +O=S(=O)(C(Cl)=Cc1cccc2ccccc12)c1ccccc1 +CC(C)n1cnc2c(Nc3cccc(Cl)c3)nc(NC3CCCCC3N)nc21 +Cc1nccc(-c2ccc(F)c(C(=O)N(C)CCO)c2)c1C#Cc1ccc(N)nc1 +COc1cccc2c3c(c(NCCO)nc12)CCN3c1ccccc1C +CCOc1ccc(-c2nc(C#N)nc3c2ccn3CC(=O)NC2CCN(C)CC2)cc1C(F)(F)F +O=C(O)CCCC=CCC1C2CCC(C2)C1NS(=O)(=O)c1ccc2sc3ccccc3c2c1 +CCCS(=O)(=O)Nc1cccc(C(=O)Nc2cnc3[nH]nc(OC)c3c2)c1F +CCOC(=O)NN=C(C)c1ccc(C(C)=NNC(=O)OCC)cc1 +CN(C)CCn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(OC(F)F)cc2)CC3)cn1 +Oc1cc(NCCCNC2CCCc3c(Cl)cc(Cl)cc32)nc2ccccc12 +Cc1c(-c2ccc(C(=O)OC(C)C)cc2)nnn1-c1cccnc1 +CCCCCCCCCN1CCc2c(C)c(CC(=O)O)c(C)c(NC(=O)C(C)(C)C)c21 +Cc1ccc(C2c3ccc4ccccc4c3Oc3nc4c(c(N)c32)CCCC4)cc1 +CN(C)C1CCN(c2ccc(NC(=O)C3CCC(c4ccccc4)CC3)cc2)C1 +CCC(O)c1cnc(C(Cc2ccccc2)CC(O)C(Cc2ccccc2)NC(=O)OC(C)(C)C)s1 +CCCN(CCC)c1nc(C)nc2c(-c3ccc(OC)cc3C)c(C)nn12 +NC(=O)c1cccc(OC2CC3CCC(C2)N3Cc2ccccn2)c1 +CCC#CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +CC(C)CCNC(=O)c1ccc2[nH]c(-c3ccc(Oc4ccccc4C(F)(F)F)cc3)nc2c1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc([S+]([O-])C(F)F)cc3)n2)CCC(Nc2ccccc2O)CC1 +O=C(CCCCN1CCCCC1)Nc1cc(-c2ccccc2)[nH]n1 +Cc1ccc2c(-c3nnc(SCCCN4CCc5ccc(-c6cc(C)nn6C)cc5CC4)n3C)cccc2n1 +COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)Cn2cc(CN(C)C)nn2)C(C)C)C(C)C)ccc1OC +Cc1cccc(C2CN(C3CCCCC3)C(=O)N2C2CCN(C(C)CCNC(=O)c3c(C)ncnc3C)CC2)n1 +O=C1NC(=S)NC1=Cc1cc2cc(-c3ccc4c(c3)COC4=O)ccc2s1 +c1ccc2ncc(N3CCC(c4nc(-c5ccncc5)no4)CC3)cc2c1 +CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(CN2CCOCC2)cc1C +c1ccc2sc(SCCCCN3CCN(CCCCSc4nc5ccccc5s4)CC3)nc2c1 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+COc1ccc2sc(CNc3nncc(-c4c(OC)cccc4OC)n3)nc2c1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc2ccccc2c1F +CNC(=O)N1CCN(c2ccnc(-n3ccnc3)n2)C(CC(=O)NCc2ccc3c(c2)OCO3)C1 +O=C(Nc1ccccc1)N1CCN(Cc2ccc(Br)cc2)CC1 +Cc1c(CC(C)C)c(=O)on1C(=O)N1CCC(c2ccccc2)CC1 +COc1ccc(NC(=O)C2Cc3ccc(OCC(=O)NO)cc3CN2C(=O)C(N)Cc2ccc(O)cc2)cc1 +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OCC(F)(F)F)ccn5)n4)ccc3[nH]2)CC1 +COCC(C)Oc1cc(C=Cc2c(F)cccc2F)cc(C(=O)Nc2ccn(C)n2)c1 +Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(C(=O)NCc1ccc(F)cc1)CC(=O)N2 +Cc1c(N2C(=O)C3C(O)CCN3C2=O)ccc(C#N)c1C(F)(F)F +O=S(=O)(NC1C2CCC1Cc1cc(OCCN3CCC(O)C3)ccc1C2)c1ccc(Cl)s1 +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(C5CN(CC(C)O)C5)cc4)c3)c(OCCOC)cc21 +NC(=O)c1cc(NCc2ncc[nH]2)cc2c(NCc3ccccc3)ncnc12 +CN1CCN(CCCNc2cc3nc(NC(=O)NC(C)(C)C)c(-c4ccccc4)cc3cn2)CC1 +CCc1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)cc(CCCNC(=O)OC)n1 +NC(Cc1ccc(O)cc1)C(=O)N1Cc2ccccc2CC1c1nc(-c2ccccc2)c[nH]1 +O=C(NCCc1nc(-c2ccccc2)cs1)c1ccccc1 +O=C1CC(CCc2ccccc2)(c2ccccc2)OC(O)=C1SCc1ccccc1 +COc1ccc2c(=O)c(C=CC(=O)Nc3cccc(Cl)c3)coc2c1 +COc1ccc(-c2nc(CNC(=O)CSC)sc2-c2ccc(OC)cc2)cc1 +CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccn3)cc2)cc1)C(=O)CCC1CCCC1 +COc1ccc2[nH]cc3nc(-c4ccon4)nc-3c2c1 +Nc1nc2c(c(=O)n(CC3CC3)c(=O)n2CC2CC2)n1S(=O)(=O)c1ccccc1 +C=C1CCC(O)CC1=CC=C1CCCC2(C)C1CCC2C(C)(O)CCCC(C)C +CC(C)(C)C(=O)OCC(CNC(=O)Cc1cc(Cl)c(O)c(Cl)c1)Cc1ccc(C(C)(C)C)cc1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1cc(Cl)cc(Cl)c1OC +CCC(F)(F)c1nc2nc(C)cc(Nc3ccc(S(F)(F)(F)(F)F)cc3)n2n1 +CCOC(O)=C1C(COCCN2CCN(Cc3ccc(Cl)cc3)CC2)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +CN(CCC#N)c1ccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +CCC(=O)c1ccc2c(c1)sc(=O)n2CCCN1CCCCC1 +CC1CN(C(=O)c2ccccc2)CCN1S(=O)(=O)c1c[nH]c2c(-n3ccnc3)ncc(F)c12 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncc(OC4CC4)cc3F)C2)cc1 +CC1(C)OC1CCC(=O)Nc1cccnc1C(=O)Nc1nccs1 +c1cc(Nc2ncnc3[nH]cnc23)cc(-c2nc3ccccc3s2)c1 +O=C(NCc1ccc(S(=O)(=O)c2ccc(N3CCOCC3)nc2)cc1)c1cnc2[nH]ncc2c1 +O=C(c1ccccc1)N1CCC(C(=O)N2CCC(Oc3ccccc3Cl)CC2)CC1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCC(F)(F)CO)ncc23)ccn1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc2cc[nH]c2c1 +O=C(Nc1cc2ccc(-c3ccncc3Cl)cc2cn1)C1CC1 +O=S(=O)(Nc1nccs1)c1ccc2c(-c3ccc(C(F)(F)F)cc3Cl)nccc2c1 +NC(CNc1nc(-c2ccncc2)nc2sc3c(c12)CCC1(C3)OCCO1)Cc1ccccc1 +C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(CN(OC)C(=O)CC)c(F)c2F)c(F)c1 +Cc1nc(-c2ccc(S(N)(=O)=O)cc2)c(-c2ccc(Cl)cc2)s1 +COc1ccc(-c2cc(N3CCOCC3)cc(=O)o2)cc1 +COc1cc(CN(CC2CC2C(=O)O)C(C)c2ccc3c(c2)CCO3)ccc1OCCN1C(=O)CCC1=O +CCCN1CCc2cc(F)cc3c2C1Cc1ccc(O)c(O)c1-3 +CCOC(=O)N1CCC(C(NS(=O)(=O)c2ccc(-c3ccc(OC)cc3)cc2)C(=O)O)CC1 +CCn1c(S)nnc1Cc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +COc1ccc(S(=O)(=O)N2CCN(C(=O)N(C)Cc3ccccc3)CC2C(=O)NO)cc1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C=Cc1ccc(CN2CCOCC2)cc1 +Cn1cc(-c2cccc(C#N)c2)c2sc(C(=N)NC3CCS(=O)(=O)CC3)cc2c1=O +COc1ccc(C)cc1N1CCN(CCn2cnc3sc4c(c3c2=O)CCN(C)C4)CC1 +CCCCC(CC)C(=O)OCC1(CO)CC(=Cc2ccc(C(F)(F)F)cc2)C(=O)O1 +CCOC(O)=C1C(COCc2cc(O)nc(CO)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +O=C1CCc2cc3cc(c2N1)OCCCCOC1CC(CO)N(C1)c1cc(n2ncc(Cl)c2n1)N3 +CC(O)(c1ccc(N(C2CCCC2)S(=O)(=O)c2ccccc2Cl)cc1)C(F)(F)F +COCCCN(Cc1ccccc1-c1ccc(CN2CCNCC2)cc1)C(=O)COc1ccccc1 +COc1cc(-c2ccccc2)nc2cc(-c3nc(C4CC(C)(O)C4)n4ccnc(N)c34)ccc12 +CCCN(CCC)C(=O)c1c(-c2ccc(Cl)cc2)nc2ccc(Cl)cn12 +CCCNC(=O)C1(C)COC(c2nc(-c3ccc(F)cc3)c(-c3ccnc(NCc4ccco4)n3)[nH]2)OC1 +Cc1ccc(C(C)NC(=O)COc2cc(C)c3c(-c4cnccn4)nn(C)c3n2)cc1 +O=C(Nc1cc(N2CCC(O)CC2)cc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1 +Nc1cc(Cl)ccc1Cn1cncc1CNc1ccc(F)c(-c2ccccc2)c1 +Cc1nc(SCC(=O)c2ccc(S(N)(=O)=O)c(Cl)c2)[nH]c(=O)c1Cc1ccccc1 +CN(CC(=O)Nc1ccccc1S(N)(=O)=O)C(=N)N +CN(c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1)c1ccc2c(C=Cc3ccc4c(c3)OCO4)n[nH]c2c1 +O=C(O)Cc1cccc(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1F +O=C1Nc2ccc(Cl)cc2C12CC2c1cc2ccccc2o1 +COc1cc2cc(C(=O)O)n(C)c2cc1OCc1ccccc1 +CCCNC(=O)c1ccc(C)c(Nc2nncc3c2cnn3-c2ccc(F)cc2F)c1 +Nc1ccn(C2OC(CO)C(O)C2O[N+](=O)[O-])c(=O)n1 +CCCCNc1nc(NC2CCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc(C(F)(F)F)nc3)n2)cn1 +N#Cc1ccccc1CSc1nnc2c3ccccc3n(C(=O)c3cccc(C(F)(F)F)c3)c2n1 +Cc1cc(N(CCNc2ccnc3cc(Cl)ccc23)Cc2ccco2)nc(N2CCOCC2)n1 +CCc1c(CNC2CCC(F)C2)nc(-c2ncccc2Cl)n1-c1ccc(C)nc1 +COc1ccc2c(c1)C(=Cc1ccc3c(C=Cc4ccncc4)n[nH]c3c1)C(=O)N2 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(Cl)cc2)CC1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NC1CCOC1 +CNC(=O)c1c(NCC2CCC3(CCC3)CC2)nc(C#N)nc1OCC1CCN(C(C)=O)CC1 +CCn1ccc2ccc(OCCCN3CCN(c4cccc5sccc45)CC3)cc2c1=O +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OCC6CC6(F)F)ccn5)n4)ccc3[nH]2)CC1 +Cc1ccc(C=CC(=O)NC(C)c2nc3scc(C)c3c(=O)o2)s1 +COc1cc(-c2ccc(F)cc2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ncco3)ccc21 +COC(=O)C1C2CCC3CCC1N(CC2=Cc1ccc(-c2ccccc2)cc1)C3 +CCn1c(=Cc2cccc[n+]2CC)sc(=C2Sc3cc(F)ccc3N2C)c1=O +COc1ccc2c(OCc3nnc4ccc(-c5ccco5)nn34)ccnc2c1 +COCCNc1cc(C(=O)O)nc2c(-c3ccc(CO)cc3)nc(N3CCOCC3)nc12 +CN1CCc2nc(C(=O)NC3CC(C(=O)N(C)C)CCC3NC(=O)c3cc4c(F)c(Cl)ccc4[nH]3)sc2C1 +NC1CCC(Nc2cc(Nc3ccc(F)c(Cl)c3)n3ncc(Br)c3n2)CC1 +CC(C)c1cc(Nc2cccc(C(F)(F)F)c2F)ncc1C(=O)NCC1CCOCC1 +CN1CCCC1CCn1c(N)nc2ccc(C(=O)c3ccccc3)cc21 +O=C(NC1COc2cccc(-c3ccc(CO)nc3)c2C1)c1ccc(OCCOCC(F)(F)F)nc1 +COc1ccc(NS(=O)(=O)c2ccc(-c3ccoc3)s2)cc1N1CC(C)NC(C)C1 +CCOC(CC(=O)O)c1ccc(OCc2cccc(-c3c(C)cccc3C)c2)nc1 +N#Cc1cc(Cl)cc(Oc2cc(CCc3cccc(Cl)c3)[nH]c(=O)c2Cl)c1 +CC(=O)Nc1cc(-c2c(-c3ccc(F)cc3)nc(SC=CC(=O)O)n2C2CCC2)ccn1 +COc1cccc2c1CCC(=O)N2CCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +O=C1C(=Cc2ccc(O)c(Br)c2)SC(=S)N1C1CCOCC1 +Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(N)=O +CC(=Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)N(CCCO)CCS(=O)(=O)O +OC1C(=Cc2cn(Cc3ccccc3)c3ccccc23)N2CCC1CC2 +Cc1ccc(Cc2cc(C3C(c4ccc(C)cc4)CC4CCC3N4C)on2)cc1 +Cc1ccc(N2CCN(C(=O)C3CN(C(C)C)CC3c3ccc(Cl)cc3)CC2)c(C(NC(=O)CN(C)C)C(C)C)c1 +Cn1c(=O)cnn(CCCCN2CCN(c3ccccc3)CC2)c1=O +Fc1ccc(NC(=S)N2CCC(c3cccc(Cl)c3)=N2)c(F)c1 +O=CN(O)C(CCCc1ncccn1)CS(=O)(=O)N1CCN(c2ccc(Br)cn2)CC1 +CC(C)Oc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(CN(C)C)n(Cc3ccccn3)c2c1 +O=C(Nc1ccc(Cl)cc1)c1cncnc1NCc1ccncc1 +CN(CCOc1ccc(-c2ccc3c(c2)OCO3)cc1-c1cccs1)CC(=O)O +O=C(C=Cc1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C2(F)F)NS(=O)(=O)c1cccs1 +Cc1csc(CNc2ncnc3ccc(-c4ccc5c(c4)OCO5)cc23)c1 +Nc1c(F)c(NCCNc2ccccn2)cc2c1c(=O)c(C(=O)O)cn2C1CC1 +CC12CCN(C(=O)C3CCCN3S(=O)(=O)c3ccccc3)C(Cc3ccccc31)C2(C)C +CCCN(c1ncc(C)c(-c2ccc(OC)cc2OC)n1)C(C1CC1)C1CC1 +CC(=O)Nc1cc(C(=O)O)cc(-n2c(C)ccc2-c2cc(Br)ccc2OCc2ccc(F)cc2F)c1 +Cc1ccc(-c2nc(NC3Cc4ccccc4C3)c3ccccc3n2)cn1 +Cn1nccc1C(O)c1ncc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)s1 +COCC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +c1ccc(-c2csc3[nH]nc(N4CC5CC4CC5OCCN4CCCC4)c23)cc1 +Cc1ccccc1-c1nc(C(F)(F)F)cn1-c1ccc(S(N)(=O)=O)cc1 +COc1cc(C(C)C(=O)NCc2ccc(C(F)(F)F)nc2N2CCCC2)ccc1CNS(C)(=O)=O +CC(C)(C)n1nnnc1C(NCCCNc1ccnc2cc(Cl)ccc12)c1ccc(Cl)cc1 +OCC1OC(c2ccc(Cl)c(Cn3nc4ccccn4c3=S)c2)C(O)C(O)C1O +CCOc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)C)n1)CCN2 +Cc1ccc(CC(=O)NCCCC[N+](C)(C)CCNC(=O)c2nc(Cl)c(N)nc2N)cc1 +O=C1CCCN1c1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(C(=O)Nc1ccc(C(F)(F)F)cc1)CC2 +Cc1ccccc1-c1ccc(CCOc2ccc(NC(=O)C(C)(N)COP(=O)(O)O)cc2)cc1 +COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CCN(C)C)cc4)sc23)c(Cl)cc1Cl +O=C1NC(=O)N(CCc2ccc(F)cc2)C(=O)C1=CC=Cc1ccccc1 +C=CCNC(=O)OC1CCC(CNC(=O)c2cc(Cl)ccc2OC)(c2ccccc2)CC1 +CCOC(=O)CCCC(=O)NC(CC(=O)O)Cc1ccc(-c2cccc(Cl)c2)cc1 +CCc1ccc(CN(C(=O)c2cc3ccccc3oc2=O)C2CCS(=O)(=O)C2)cc1 +Cc1cccc2c1c(=O)n(CC1CCC(C(=O)O)CC1)c(=O)n2Cc1cccc(C(F)(F)F)c1C#N +O=C(Cn1c2c(c(-c3cc(Cl)ccc3Br)cc1=O)C(=O)CC2)Nc1ccc(-c2noc(=O)[nH]2)cc1 +CN(C)CCNc1ncc2ncnc(Nc3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3F)c2n1 +OC(c1cnc(N2CCN(c3ccccc3)CC2)s1)(C(F)(F)F)C(F)(F)F +CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(C(F)(F)F)cc3)[nH]2)CC1 +Cc1cc2c(c(Oc3cccc(NS(=O)(=O)c4ccc(Cl)cc4)c3)n1)C(=O)N(C1CCCC1)C2=O +O=C(Cc1cccc2[nH]ccc12)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccc4[nH]ccc34)s2)s1 +CCOC(=O)c1c(C)nc(-c2ccccc2)c(C(=O)OCC)c1CC +COc1ccc(C2=NN(C(C)=O)C(c3ccc(Cl)c(Cl)c3)O2)cc1 +COc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(C)=O)CC3)c1 +Cc1cc(COc2ccc(S(=O)(=O)NCC(C(=O)NO)N3CCCCC3)cc2)c2c(n1)CCCC2 +CCCn1c(=O)c2[nH]c(-c3cc(OCC(=O)Nc4ccc(Br)cc4)n(C)n3)nc2n(CCC)c1=O +CCC(=O)N1CCc2cc(-c3cncc4ccccc34)ccc21 +COc1cc(-c2ccccc2Cl)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CCCCN1C(=O)C2Cc3c([nH]c4ccccc34)C(c3ccsc3)N2C1=O +COC(=O)C1=CNC=C(C(=O)OC)C1c1ccc(Cl)c([N+](=O)[O-])c1 +Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)C3CCC(F)(F)C3)CC2)c1 +COc1ccc(CCN2C(=O)N(CCN(C)C)C(=O)C23CCN(Cc2ccc(O)cc2)CC3)cc1 +NC1(C(=O)NC(c2ccc(Cl)cc2)C2CC2)CCN(c2ncnc3[nH]ccc23)CC1 +O=C(Nc1cc(Br)cc2c(=O)cc(C(=O)O)oc12)c1ccc(Cl)c(Cl)c1 +Cc1ccc(-c2nn3c(C)nnc3c3ccccc23)cc1S(=O)(=O)N(C)C +CN(C)c1ccc2cc(C(=O)NC3CCC4(O)C5Cc6ccc(O)c7c6C4(CCN5CC4CC4)C3O7)ncc2c1 +Cn1cc(-c2cc(F)c3nnc(Sc4ccc5ncc(N6CCC(F)(F)CC6)cc5c4)n3c2)cn1 +CC1(c2ccc(F)cc2)NC(=O)N(CC(O)CN2CCN(c3ccc(F)cc3)CC2)C1=O +NC(=O)C1CCC(CNc2nc(NCc3ccccc3)cc(-c3cccnc3)n2)CC1 +O=C1N(CCN2Cc3ccccc3C2)CCN1Cc1cccc(C(F)(F)F)c1 +CCC(COC)N1CCn2nc(-c3ccc(Cl)cc3Cl)c3nc(C)cc1c32 +CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nc2ccccc2n1-c1ccccc1C(F)(F)F +O=c1ccc2cnc(Nc3ccc(N4CCC(CCCO)CC4)cc3)nc2n1C1CC2CCC1C2 +CCN(CC)C1CN(C(=O)c2cc3cc(Nc4nccc(-c5ccccn5)n4)ccc3[nH]2)C1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4(CCC4)C3)n2)cc1OC(F)F +CNc1cc(Nc2cnc(C#N)c(OC(C)CN(C)C)n2)ncc1-c1cnn(C)c1 +O=C(c1ccc(Oc2ccccc2)cc1)c1cc2c(OCCN3CCNCC3)cccc2[nH]1 +CCCc1c(OCCCCOc2ccc(-c3nn[nH]n3)cc2)ccc2c1cnn2CC(C)(C)C +COC1CCC(NC(=O)c2cc(C)n(Cc3cc(Cl)cc4cc(C(C)C)oc34)n2)CC1 +Cc1nc(Nc2cccnc2)cc(-c2c(Nc3cc[nH]n3)nc3cccnn23)n1 +NC1CCC(Nc2cc(-c3cccc(NCc4cccc(C(F)(F)F)c4)n3)c(Cl)cn2)CC1 +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)N2CCC(C(=O)O)CC2)sc2ccccc12 +CNC(C)c1ccc2c3c(c(=O)[nH]c2c1)CCCN3 +COc1ccc(C2CN(C)Cc3cc(OCCCN4CCCC(F)(F)C4)ccc32)cc1 +Cc1csc(CNc2nc3c(S(=O)(=O)c4ccc(C(C)(F)F)cc4)nnn3c3ccsc23)c1 +CCCS(=O)(=O)c1ccc2c(c1)N=C(c1ccc(C(=O)O)cc1)c1cc3c(cc1N2C)C(C)(C)CCC3(C)C +CC1CN(Cc2c[nH]nc2-c2ccc3c(c2)CNC(=O)N3)CCN1c1ccc(C(F)(F)F)cn1 +OCCCCNc1nc(Nc2ccccc2)nc(Nc2ccc(F)cc2)n1 +COc1ccc(C2(Cc3ccncc3)C(=O)N(C(=O)OC(C)(C)C)c3ccccc32)cc1OC1CCCC1 +CC(=O)OC12CC3CC(CC(NCC(=O)N4CCCC4C#N)(C3)C1)C2 +CN(C)C1CCc2nc(NC(=O)c3cccc(CNC(=O)c4ccc(-c5ccncc5)s4)c3)sc2C1 +O=C1c2ccc(-c3nc4ccc(F)cc4s3)cc2N=CC2CCCN12 +CCCNC(=O)c1ccc(F)c2c1CC(N(CCCc1c[nH]c3ccc(F)cc13)C1CCC1)CO2 +CC(C)(C)c1ccc(-c2ccc(CCC(=O)N3CCCC3c3ncc(-c4ccccc4)[nH]3)cc2)cc1 +COCCN1CC(C)(C)Oc2nc(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)Nc4ccon4)c(F)c3)c2C1=O +CC(C)CC1CCCC(NC(=O)C(S)Cc2ccccc2)C(=O)N1CC(=O)O +CNCc1ccc(C(F)(F)F)cc1Oc1ccc(Cl)c(Cl)c1 +O=P(O)(O)CNC(Cc1ccc(-c2ccccc2)cc1)c1nn[nH]n1 +O=C(O)C(Cc1ccccc1)Oc1ccc(COc2ccccc2)cc1 +COc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2CCO)cc1C +CC1(C)CCNCC1Oc1cncc(-c2n[nH]c3ccc(-c4c(F)cccc4F)cc23)n1 +N#Cc1c(NCc2ccc(Cl)cc2)nn2c(=O)cc(Cc3ccoc3)[nH]c12 +O=[N+]([O-])c1cn2c(n1)SC(COCc1ccc(Oc3ccccc3)cc1)C2 +NC(CNc1nc(-c2ccncc2)cc2cnccc12)Cc1ccccc1 +COc1ccc(Cl)c(Nc2ncnc3cc(OC)cc(OCCCN4CCOCC4)c23)c1 +CC1=C(C(=O)N2CCCC2c2ccc(F)cc2)C(c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 +COCCn1c(C)c(C(C)(C)C)sc1=NC(=O)c1ccc(C(F)(F)F)cc1 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+N#Cc1ccc(-c2cc(COCC3(c4ccccc4)CCNCC3)cc(C(F)(F)F)c2)cn1 +CC1C(O)CCC2(C)C1CCC1C3CC=C(c4cccnc4)C3(C)CCC12 +CC(N)(CF)c1nc(-c2ccc(OC(F)(F)F)cc2)c[nH]1 +CC(C)CC(N)c1cc(Cl)ccc1N1CCN(C(=O)C2NCCC2c2ccc(Cl)cc2Cl)CC1 +CN1C(=O)C(=Cc2ccc3c(c2)OCO3)N=C1Nc1ccc2c(c1)OCCO2 +CC(CCC(SCCC(=O)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)CC(=O)N(C)C +COc1cc(C2=NCCN2)cc2cc(CCCCCc3cc4cc(C5=NCCN5)cc(OC)c4o3)oc12 +COc1ccc(Oc2ccc(S(=O)(=O)Cc3cccn(O)c3=O)cc2)cc1 +COCCOc1cccc2oc(-c3cn4nc(OC)sc4n3)cc12 +Nc1nc(Nc2ccc(N3CCN(C4CC5CCC4C5)CC3)c(Cl)c2)nn1-c1ncnc2sccc12 +COc1ccc(OC)c(-c2ccc(O)c(CN3CCCCCC3)c2)c1 +NCC1CN(c2nc(N)nc3c2oc2ccc(Cl)cc23)C1 +Cc1cc(COc2ccc(C(=O)NC3(CC(=O)NO)CCN(CCF)CC3)cc2)c2ccccc2n1 +CC(C)(C)c1ccc2c(c1)C1OCCCC1C(c1cccs1)N2 +N#Cc1cccc(-c2nc(N3CCC(C(N)=O)CC3)cc3cccnc23)c1 +CCCN1CCC2c3c(cccc3C(=O)C(C)C)CCC21 +CCCCCCCCC=CCCCCCCCC(=O)NCCc1ccc(OC)cc1OC +CN1CCN(Cc2cccc3c2ccn3S(=O)(=O)c2ccccc2)CC1 +O=C(O)c1cccc(Oc2ccc3c(c2)CC(NCC(O)c2ccc(Cl)nc2)CC3)c1 +CS(=O)(=O)N1CCC(c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccccc3)n2)CC1 +CCn1c(=O)c2nc(-c3ccc(S(=O)(=O)N4CCSCC4)cc3)[nH]c2n(CC)c1=O +CC(C)(C)OC(=O)N1CCC(NC(=O)NCc2cn(-c3ccccc3)c3cc(Cl)ccc3c2=O)CC1 +CC1CN(C(=O)N2Cc3c(NC(=O)c4ccccn4)n[nH]c3C2(C)C)C(C)CN1CCC1CCOCC1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NC(C)c3cccc(Cl)c3F)CC3CC32)c2cnccc12 +CC=CCn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc21 +Cc1cc(F)ccc1C(=C(C=CC(O)CC(O)CC(=O)O)c1nnnn1C)c1ccc(F)cc1C +COc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)cc1 +CCCc1cnc(N2CCC(C3Cc4c(ccc(C5=CCN(S(=O)(=O)CCC)CC5)c4F)O3)CC2)nc1 +CC(=O)NC(C)c1ccc(C2CN(c3ncnc(OCC4CC4(F)F)c3F)C2)cc1 +CN(Cc1ccccn1)c1ccc(C#N)cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(C#N)cc12 +CCCc1nc(CC)c(C(=O)OC)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)C2CC2)cc1 +CCC1CNCCN1c1c(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)cnn1C +CCc1cc(-c2ncnc(CC)c2C#Cc2ccc(N)nc2)ccn1 +O=C(NNc1ncnc2sc3c(c12)CCC3)c1ccccn1 +COc1cc(OC)cc(N(Cc2ccco2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +COc1cc2c(cc1OC)C1CC(O)C(CC(C)C)CN1CC2 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1Nc1ccc(OCCO)cc1CC2 +CN(C)c1ccnc2sc(S(=O)(=O)c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c12 +NS(=O)(=O)Nc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +O=C(c1nn(-c2cccc(F)c2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +NC(=S)NN=C1CCS(=O)(=O)c2ccc(Br)cc21 +CCN(CC)Cc1cc(C=NN=C(N)CC(O)c2cc3ccccc3c3ccccc23)ccc1O +CCc1cccc2onc(NCC(C)(C)c3ccccc3)c12 +CC(=O)c1ccc(OCCCN2CCN(Cc3ccccc3)CC2)cc1O +Cc1ncc(C#Cc2c(C)ncnc2N2CCOCC2)cc1NS(=O)(=O)c1ccccc1Cl +Cc1ccc(NC(=O)c2ccno2)cc1-c1ccc(C(=O)NCC2CC2)cc1 +OCC1NC(=NCc2ccc(C(F)(F)F)cc2)C(O)C(O)C1O +Cc1cc(Cl)c(OCCOc2ccc(CC(CN)c3ccc(-c4ccccc4CCOC(N)=O)cc3C)cc2)c(Cl)c1 +CN1C(=N)NC(C)(c2sc(-c3cncc(-c4nnc(C5CC5)o4)c3)cc2Cl)CS1(=O)=O +CCC(CNc1cc(C)nc2c1NC(=O)CN2c1ccc(Cl)cc1Cl)OC +CCOc1ccc2nc(NC(=O)CS(=O)(=O)Nc3nc4ccc(OCC)cc4s3)sc2c1 +C#CC(CC(=O)O)NC(=O)CN1CCc2ccc(-c3ccncc3)cc2C1=O +COCC(NC(=O)Nc1cc2[nH]nc(N3CCC(O)CC3)c2cn1)c1ccccc1 +CCc1cccc(N2C(=O)CN(C3CCN(CC4=CCC5CC4C5(C)C)CC3)C2=O)c1 +O=C(O)CCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1ccc[n+]([O-])c1 +COc1cccc(C2OC(CCC(=O)N3CCC(COCC(=O)O)CC3)c3cccn3-c3ccc(Cl)cc32)c1OC +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3cc(C)c(OC)nc3C)ccnc21 +CN(C(=O)C(Cc1ccccc1)NC(=O)c1ccc2c(c1)OCCO2)N(C#N)CCc1ccccc1 +COC(=O)CCCCC(CCSSC(CCO)=C(C)N(C=O)Cc1cnc(C)nc1N)SC(C)=O +CS(=O)(=O)c1ccc(-c2c(Br)sc(Br)c2-c2ccc(F)cc2)cc1 +CCN(CC)CCCNc1ccc(C(F)(F)F)cc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +CCCN(CCC)CCc1ccc(OC)c(OCCc2ccc(F)cc2)c1 +N=C(N)Nc1cccc(C(=O)NNC(=O)NC(CC(=O)O)c2cc(Cl)cc(Cl)c2)c1 +COc1ccccc1N1CCN(C2CC3CC(NC(=O)c4ccc5ccccc5c4)CC3C2)CC1 +CC1=C(CCN(C)C)c2cc(NS(=O)(=O)c3csc4ccccc34)ccc2C1 +CCCc1[nH]c(=O)c(Cc2cc3cc4c(cc3nc2N(C)C)OCO4)c2cc(OC)c(OC)cc12 +CCN(CC)C(=O)C=C(C)c1ccc(OC(C)c2ccccc2)cc1 +NC(=O)c1cc(N(CCCl)CCBr)c([N+](=O)[O-])cc1[N+](=O)[O-] +O=C1NCCn2c1cc1cc(OC3CCN(CC4CC4)CC3)ccc12 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccc(C(F)(F)F)cc2)cc1 +COC1=CC(=O)C(=O)C(CCCCCCCCCCCO)=C1OC +Cc1cncc(-c2cc3c(cn2)cnn3-c2ccc(C#N)c(N3CCCC(N)C3)n2)n1 +CC(Sc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br)C(C)(C)O +CC(C)Oc1ccccc1N1CCN(Cc2cccc(C(=O)N3CCC(O)CC3)c2)CC1 +CN(C)CCn1c2ccc(O)cc2c2c3c(c(-c4ccccc4)cc21)C(=O)NC3=O +COCC1CCCN1CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +CC(O)CNC(=O)C(Cc1cccs1)N(C)C(=O)C(Cc1ccc2ccccc2c1)N(C)C(=O)C=CCC(C)(C)N +CC(C)S(=O)(=O)c1ccccc1Nc1nc(NC(=O)N2CCCc3ccc(C=O)nc32)ncc1Cl +COC(=O)Nc1nc2c(C)cc(C(=O)c3cccs3)cc2[nH]1 +CNC(=O)Nc1ccc(-c2nc(CS(=O)(=O)C3CCCCC3)cc(N3CCOCC3C)n2)cc1 +CCN(CC)c1cccc(NC(=O)Nc2ccc(C)c(Nc3nccc(-c4cccnc4)n3)c2)c1 +CCc1sc(CCc2cc(OCC3(C)CC3)cc(NCc3cc(Cl)cc(NC(=O)OC(C)C)c3)n2)nc1C +CCCCC=CN(NC(C)=O)C(=O)C(CO)N=[N+]([O-])CCCCCC +N=C(N)c1ccc(O)c(CN2CCC(NS(=O)(=O)c3ccc(-c4cccnc4)s3)C2=O)c1 +CC(C)C1CCCC(C2(OC(=O)N3CCN(C(C)(C)CO)CC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CC(C)(C)CC(=O)Nc1sc2c(c1C(=O)NCC1CC1)C(C)(C)CC2 +Cc1cc(Nc2nn(-c3cccc(-n4ncc5cc(C(C)(C)C)ccc5c4=O)c3CO)cc2C(N)=O)nn1C +O=C(NC1(c2nccs2)COC1)c1cc(OCC2CC2)c(Cl)cn1 +CSc1nc(NCCCCNc2ccnc3cc(Cl)ccc23)c(C#N)c(-c2ccc([N+](=O)[O-])cc2)n1 +CC(C)(C)NCc1c(-c2ccccc2)nc2cc(C=CC(=O)NO)ccn12 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+COc1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cc1Cl +CCN(CC)c1ccc(C=NNC(=O)CNC(=O)C2COc3ccccc3O2)c(O)c1 +COc1ccc(CCN(C)CCCCc2cn(-c3ccc(F)cc3)c3ccccc23)cc1 +CCc1ccc(-c2ccc(S(=O)(=O)NCCc3c[nH]c4ccccc34)cc2)cc1 +CCN1C(COc2ccccc2)C(O)C(O)C(COc2ccccc2)N(Cc2ccccc2)S1(=O)=O +CCN(CC)CCN(C)Cc1ccc(Nc2nnc3cc(-c4cc(O)ccc4Cl)cc(C)c3n2)cc1 +NC1(c2ccc(-c3nc4ccc(Br)cn4c3-c3ccccc3)cc2)CCC1 +COc1ccc(CC(N)C(=O)N2CCN(c3ncnc4ccccc34)CC2)cc1 +CC(C)Nc1cc(-n2ccc3cc(CNC(=O)CC(C)(C)O)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +Cc1ccccc1C1CN(C)CC1NC(=O)N1CCc2[nH]nc(-c3ccc4c(c3)CCO4)c2C1 +O=C(NC1CCCCN(CCc2cccc(F)c2)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +CCOCN1C2=C(C(=O)Nc3c(F)cccc3F)C(=O)CCN2c2ccc(F)cc21 +CCOc1cc2ncnc(Nc3ccc(F)c(-c4csc(C)n4)c3)c2cc1OCC +Nc1ncnc2c1C(=O)N(c1ccc(C3CCC(CCC(=O)O)CC3)cc1)CCO2 +COc1ccc(C2CNCc3cc(OCCCN4CCOCC4)ncc32)cc1 +CC(C)N1CCC(Oc2ccc(-c3ccc(=O)n(C)n3)cc2)CC1 +O=C(Cc1ccccc1)Nc1ncc(C(=O)NCCc2ccccc2)c2nc(-c3ccco3)nn12 +CN(c1ccc(Cl)cc1)c1ccc(C(=O)c2ccc(C(=O)c3cccc(OC(F)(F)F)c3)c(C(=O)O)c2)nc1 +COc1ccc(S(=O)(=O)NC2CCN(CCOc3ccccc3OC)CC2)cc1OC +Cc1cc(N)nc(C)c1CNC(=O)C1CCCN1C(=O)C(NC(=O)OC(C)(C)C)C(C1CCCCC1)C1CCCCC1 +N#Cc1ccc2c(-c3cc4cc(CN5CCOCC5)ccc4[nH]3)n[nH]c2c1 +Cn1cnc(-c2ccnc(Nc3cc(Cl)c4[nH]c(C(=O)N5CCn6cnnc6C5)cc4c3)n2)c1 +O=C1NC(=O)C(Cc2ccc(Oc3cccc4ccccc34)cc2)S1 +COc1cc(C=C(C#N)c2nc3cc(C)ccc3[nH]2)c(Br)cc1O +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(F)c1 +COC(=O)c1c(Cl)cccc1-c1ccc2c(c1)CCC2NC(=O)C1(NC(=O)C(F)(F)F)CC1 +COC(=O)c1cccc(CCC(SCC(C)C(=O)O)c2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)c1 +CCc1cc(C(F)(F)F)ccc1C(=O)NCc1cccc(Oc2ccc(OC(C)(C)C(=O)O)c(C)c2)c1 +O=C(NS(=O)(=O)C1CCOC1)c1cc(C2CC2)c(OCC23CC4CC(CC(C4)C2)C3)cc1F +CN(C)CC(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +CCOC(=O)c1c(Cl)cccc1-c1cnc(C(C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1 +C=C(CCC(C)C1CCC2C3=C(C(=O)CC21C)C1(C)CCC(O)C(C)(O)C1CC3=O)C(C)C(=O)O +Cc1c(Cc2ccccc2)nnc(N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c1C +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCCC5(CNC(=O)C5)C4)c23)c1 +O=C(c1ccccc1)c1c2c(cc3sc4ccccc4[n+]13)-c1cccc3cccc-2c13 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+CCCC1OC(C#CC2CC2)(C(F)(F)F)c2cc(Cl)ccc2NC1=O +COc1ccc(-c2ccc3c(c2)SN2CCCN=C32)cc1 +Cc1ccc(Oc2ccc(NC(=O)CCC(N)C(N)=O)cc2)cc1 +CC1CCCN1c1cccc(Nc2cc(-c3ccc(O)cc3)nn3ccnc23)n1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCCc1cccc(I)c1 +NCC#CCN(Cc1nc2ccccc2[nH]1)C1CCCc2cccnc21 +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CC=C(C#C[Si](C)(C)C)CC1 +Cc1nccn2c(-c3ccnc(NCC(C)(C)CO)n3)c(-c3ccc(F)cc3F)nc12 +CCOc1ccccc1-c1nnc2ccc(-c3ocnc3-c3ccc(F)cc3)cn12 +COc1ccc(C(=O)Nc2cc(C(=O)NC(=N)N)ccc2OCCCN2CCN(Cc3ccc(OC)c(OC)c3OC)CC2)cc1 +COc1ccc(C(=O)N2c3ccccc3[S+]([O-])c3ccccc32)cc1O +Cc1cccc(C)c1OCC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12 +O=C(c1cccc(Cl)c1Cl)N1CCc2c(ncn2-c2ccn[nH]2)C1 +CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(-c3nc(C)no3)cc2F)CC1 +O=C(Nc1ccc2cnn(-c3ccc(Br)cc3)c(=O)c2c1)c1c(F)cccc1Cl +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NCC(c1cccc2ccccc12)N1CCC(N2CCCCC2)CC1 +Cc1nc2c(OCCF)cccc2n1-c1ccc(C(=O)NC2CC2)s1 +Cc1cc(C)n(CC(=O)NN=Cc2cc(Br)cc([N+](=O)[O-])c2O)n1 +O=c1[nH]cnc2cc(C3NC(CO)C(O)C3O)[nH]c12 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+O=C1Nc2cc(C(=O)C3CCCN3)ccc2C1=C(Nc1ccc(CN2CCCCC2)cc1)c1ccccc1 +CCCN1Cc2c(c3cc(OC)c(OC)cc3c3cc(OC)c(OC)cc23)C(O)C1 +CC1Cc2c(ccc(F)c2F)N1C(=O)Cc1nc(N2CCOCC2)c(F)c(=S)[nH]1 +Cc1nc2nc(-c3ccc(CN4CCC(c5n[nH]c(-c6cnccn6)n5)CC4)cc3)c(-c3ccc(F)cc3F)cn2n1 +CC(C)(COc1ncc(-c2ccc(-c3ncc(C(F)(F)F)[nH]3)c(Cl)c2)cc1F)C(=O)O +CS(=O)(=O)N1CCC(Nc2ncc(C(=O)c3c(F)cccc3F)c(N)n2)CC1 +c1cc(-c2ccc(OCCCN3CCCCC3)cc2)ccc1CCCN1CCCCC1 +O=C(NCCCCCCNc1ccnc2cc(Cl)ccc12)NC1C(=O)N(C2CCCCC2)C1C=Cc1ccccc1 +Cc1nc(NC2CCCc3cc(N)ccc32)cc(-c2ccc3ncsc3c2)n1 +COc1ccc(Cn2cnc3c(N(C)C)nc(C(F)(F)F)nc32)cc1C +NC(=O)c1ccc(F)c2c1CC(NCC1CCc3[nH]c4ccc(F)cc4c3C1)CO2 +CNC(=O)c1ccc(-c2cnc3ncc(Cc4ccc5ncccc5c4)n3n2)cc1C +CCCCS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)NC(c1c(O)c3cccnc3n(CCC(C)C)c1=O)=N2 +CNCc1cc(F)ccc1Oc1ccc(-c2ccccc2)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccc(CN5CCCC5)cc4)nc23)N1 +CC(C)N(C(=O)CN1C=CN(c2ccccc2)C(=O)C(Cc2n[nH]c3ccccc23)C1=O)c1ccc(O)cc1 +N#Cc1ccnc(Nc2cc(C3(C#N)CCOCC3)cc(N3CCC(F)(F)C3)n2)c1 +Nc1nc(N)c2cc(NCc3cccc4c3CCCC4)ccc2n1 +C=CCCCCCCCCCCn1nnc(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccccc2)n1 +CCCCN(CC)c1cc(C)nc2c1NCCN2c1ccc(C(C)=O)cc1C +O=c1c(=O)c2ccc([N+](=O)[O-])c3c([N+](=O)[O-])ccc1c32 +CSc1nc(NCc2ccccc2)c2c3c(sc2n1)CN(C)CC3 +NC(=O)c1cnc(NC2CCCCC2)c2c1[nH]c1cc(-c3ccn[nH]3)ccc12 +Fc1ccc(-n2ncnc2-c2cc3c(s2)-c2ccccc2OCC3)c(F)c1 +COc1ccc(C2(C#N)CCN(C(C)C(=O)NO)CC2)cc1OC1CCCC1 +O=C1NC(NCCO)=NC1=Cc1c[nH]c2ncccc12 +O=C(C=Cc1ccc2c(c1)C(=O)CC1(CCCN(CCc3ccccc3)CC1)O2)NO +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cccnc2[nH]1)C(F)(F)F +Clc1ccc(-c2cc(C3CCCCC3)c(-c3ccncc3)[nH]2)cc1 +O=C(Nc1ccc(Cl)cc1)N1CCN(CC2CCCN(C3CC3)C2)CC1 +COC(O)=C1C(C)=NC(C)=C(C(=O)NCCCN2CCC(c3ccccc3)(c3ccccc3)CC2)C1c1ccc(C)cc1 +CC(C)c1n[nH]c2c(NCc3ccc(-c4ccccn4)cc3)nc(NCCN(C)C)nc12 +O=C(NC1CCC(CO)CC1)c1cn(Cc2ccc(-n3cccn3)cc2)c2cccnc12 +N#Cc1cncc(Nc2ncc(-c3ccncn3)c(-c3ccco3)n2)c1 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1cccc2c1CCC2 +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2ccc(OC)c(OC)c2OC)cc1 +CC#CC1CN(S(=O)(=O)c2ccc(N)nc2)CCN1c1ccc(C(O)(CO)C(F)(F)F)cc1 +CN1C(=N)NC2(c3cc(-c4cccc(C#N)c4)cs3)CN(c3ncc(F)cn3)CC2C1=O +COC(=O)c1cccc(-c2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +O=c1sc2ccccc2n1CCCCN1CCN(c2ccccc2)CC1 +c1ccc(CCN2C3CCC2CC(N2CCC(c4c(-c5ccccc5)[nH]c5ccccc45)CC2)C3)cc1 +C=C(C=O)C1CC(=O)C(C(=O)OC)C2OC(C)(CC2=O)CC2OC(=O)C3(OC23)C(OC(C)=O)C1 +COc1ccc(C(=O)C(C)[n+]2cccc3ccc4cccnc4c32)cc1 +Nn1c(-c2ccc(-c3ccccc3)s2)n[nH]c1=S +CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)N(CCCN(C)C)c3ccc(Cl)cc32)c1C +Cc1n[nH]c2ccc(-c3cncc(SCC(N)Cc4c[nH]c5ccccc45)c3)cc12 +Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1cccnc1OCCN1CCCC1 +CCCn1c(=O)c2nc(-c3cnn(Cc4cc(Cl)ccc4Cl)c3)[nH]c2n(CCC)c1=O +CC(=O)c1cccc(NC(=O)Nc2cc3c(cc2C[N+]2(C)CCC(Cc4ccc(F)cc4)CC2)OCO3)c1 +CC(C)c1nc(N(C)S(C)(=O)=O)nc(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)NO +CN(C(=O)C=Cc1ccoc1)C1CCC2(O)C3Cc4ccccc4C2(CCN3CC2CC2)C1 +C#CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)sc2Cl)cc1 +COc1ccc(-c2c3c(nn2C)CCc2cnc(Nc4ccc(C(=O)NC5CCN(C)CC5)cc4OC)nc2-3)c(Cl)c1 +Nc1ncc(-c2ccc(C3(c4noc(-c5cnccn5)n4)CCC3)cn2)cn1 +CCc1ccc2[nH]c(=O)c(CN(Cc3ccc(OC)cc3)C(=S)NCCCN(CC)CC)cc2c1 +COc1ccccc1S(=O)(=O)NC(=O)N1CCC(N2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)CC1 +CC(C)Oc1ncccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +COc1ccc(N(Cc2csc(-c3ccccc3)n2)S(=O)(=O)c2ccccn2)cc1 +Cc1[nH]nc2c1N=C(c1ccccc1Cl)c1cc([N+](=O)[O-])ccc1N2 +O=c1c(Nc2ccccc2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 +Cc1cccc(C)c1N1CC(CN2CCCCC2)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(C)C1=O +OC(CCN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1)c1cccc(F)c1 +COc1ccc(CNc2ncccc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)cc1 +CCn1cc(C2(c3ccc(F)c(-c4cccnc4F)c3)N=C(N)N(C)C2=O)cn1 +Cc1ccc(-c2cc3c(NC4C5CC6CC4CC(O)(C6)C5)c(C(N)=O)cnn3c2)cc1 +O=C(CN1CCC(c2nnc(-c3ccccc3)o2)CC1)NCc1nc2c(c(=O)[nH]1)COCC2 +O=C(NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCN2CCCC2)N1)c1ccc2cc(Cl)ccc2c1 +COc1cccc(-n2cc3nc(-c4cccnc4C)n(CC4CCCN(Cc5cnco5)C4)c(=O)c3n2)c1 +CN1c2ccc(-c3cnc(N)c(Cl)c3N3CCC4(CC3)CNC(=O)O4)cc2CS1(=O)=O +Cn1ncc(NC(=O)c2csc(-c3c(F)ccc(C4CC4)c3F)n2)c1C1CCC(N)C(F)CO1 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+O=S(=O)(NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1)c1ccccc1 +CCCCCC=CCC=CCCCCCCCCNC(CO)Cc1ccc(O)cc1 +O=[N+]([O-])c1cc(CNCCP(=O)(O)O)c2nc(O)c(O)nc2c1 +O=C(c1ccncc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +Cc1cncc(C(=O)Nc2cccc(CN3CCCC(C(=O)NC(C)(C)C)CC3)c2)c1 +CC(=O)c1cc2c3c(cccc3c1)C(=O)N(CC(=O)O)C2=O +CC(CCC(=O)O)(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +O=C(Nc1cc(Br)cc2c(=O)cc(C(=O)O)oc12)c1ccccc1 +O=C(Nc1ccc(CN2CCCCC2)cc1)Nc1ccc2ncnc(Nc3cccc(C(F)(F)F)c3)c2c1 +O=C(NN=Cc1cc(Cl)c2ncccc2c1)C1CC1c1cccc(Cl)c1 +NC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)C1CCN(C(=O)C(N)Cc2ccc(O)cc2)C1 +O=S(=O)(c1ccccc1)n1c2c(c3ccccc31)CCNCC2 +O=C(N1CCc2cc(O)ccc2C1c1cccs1)C(F)(F)F +COc1cc2ncnc(N3CCN(C(=O)NCc4ccc(C(C)(C)C)cc4)CC3)c2cc1OC +CN1CCN(c2ccc(OC(C)(C)C(=O)NC3C4CC5CC3CC(C(N)=O)(C5)C4)nc2)CC1 +O=C(Nc1cc(Nc2ccc3c(c2)CCCCC3=O)ccc1F)c1ccccc1 +c1ccc(CNCCCNCCCCCCCCCCCCNCCCNCc2ccccc2)cc1 +NC(=O)COc1cccc(CN2CCC(Nc3cccc4cnccc34)C2)c1 +NC(=O)N1CCCc2cc(-c3cncc(F)c3)cnc21 +N#Cc1nc(-c2ccc(OCCC3CCN(CCO)CC3)c(C(F)(F)F)c2)c2ccn(CC3CCCO3)c2n1 +CCOC(=O)c1c(N2CCN(C)CC2)nc2cccc3c2c1-c1ccccc1-3 +Nc1c(C(=O)c2cc3ccccc3[nH]2)cnn1-c1ccc2[nH]ccc2c1 +Cc1ccc(NC(=O)CCC(F)(F)F)cc1N1CCc2nc(Nc3ccc(OCCN4CCCC4)cc3)ncc2C1 +N#Cc1cc(NS(=O)(=O)c2ccccc2C#N)ccc1Cl +COc1ccc(-n2cnc3ccc(-c4nnc(SCc5cccc(C(F)(F)F)c5)o4)cc32)cc1 +COc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3oc(C)c(OC)c3c2Cl)cc1 +CCc1cccc(CC)c1NC(=O)c1cn(C)c2c1CCCc1cnc(Nc3ccc(N4CCN(C)CC4)cc3OC)nc1-2 +CCCNc1ncc(-c2ccncc2-c2ccc(OC)cc2C(F)(F)F)s1 +COc1ccc(Oc2c(Cl)cnn(Cc3cccc4ccccc34)c2=O)cc1OC +NC1CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cc2-c2cncnc2)C1 +CC(CO)(CO)C(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)CC1CCCC1 +CCOc1ccc(C(CC)Nc2nc(N3CCN(C(C)=O)CC3)nc3c2CN(C(C)C)C3=O)cc1 +c1ccc2c(c1)c1c(n2Cc2ccc(Cn3c4c(c5ccccc53)CCCCC4)cc2)CCCCC1 +O=C(C1CC(N2CCN(c3ncccn3)CC2)CN1)N1CCC(F)C1 +CCC(=O)Nc1ccc(Sc2nc(C)cc(Nc3cc(C)[nH]n3)n2)cc1 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-c3cc[nH]n3)ncnc12 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+CC1CN(C(=O)OC2(C(F)(F)F)COC2)CCN1c1ncc(OCc2ccc(CS(C)(=O)=O)cc2F)cn1 +O=S(=O)(c1ccc(F)cc1)N1CC=C(CCc2ccc(F)cc2F)CC1 +NC(=O)c1ncc(NC2CCCCC2N)cc1C#Cc1ccccc1 +Nc1nccc(Oc2ccc(NC(=O)C3CCCN(c4ccccc4)S3(=O)=O)cc2F)c1Cl +Cc1ccc(CC(COC(=O)C(C)(C)C)CN(O)C(S)=NCc2ccc(NS(C)(=O)=O)cc2F)cc1C +Cc1ccc(OCC2CCC(C(=O)N3CCCC3C#N)N2)cc1 +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(Cl)c3)n3c2CCOCC3)cc(C)n1 +COc1cc(OCCCON=C(N)N)cc(OS(=O)(=O)c2ccccc2S(C)(=O)=O)c1 +Nc1onc(-c2ccc(F)cc2)c1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C1NC(=O)c2c1ccc1c2c2cc(O)ccc2n1CCC(=O)N1CCOCC1 +COc1cc(OCc2csc(N3CCN(C)C(C)C3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +O=C(CCCCCSc1nc(Cc2ccccc2)cc(=O)[nH]1)NO +CC12CCC3C(CC(=CCO)C4CC(=NOCCN)CCC43C)C1CCC2=O +CCOC(=O)c1c(CSc2cc(Cl)cc(Cl)c2)[nH]c2c1cc(O)c1ccccc12 +Cc1c(NC2CCOCC2)cccc1C(=O)NCC(O)CN1CCc2ccccc2C1 +O=C1Nc2ccc3ncsc3c2C1=CNc1ccc2c(c1)CS(=O)(=O)C2 +O=C(NCCC(c1ccccc1)c1ccccc1)c1ccc(=O)[nH]c1 +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)O +COc1cc(OCc2cccc(C3=CCOCC3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=S(=O)(c1ccc(F)cc1)C1(F)CCN(CCc2ccc(F)cc2F)CC1 +O=C(Nc1ccccc1)Nc1cccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)c1 +CC(C)c1ccc(C=C2SC(=O)N(CC(=O)NCCCn3ccnc3)C2=O)cc1 +N#Cc1ccc2cc(-c3cc4cc(CN5CCC(CN)CC5)ccc4[nH]3)c(=O)[nH]c2c1 +C#CC1CCC(C#N)N1C(=O)CNC1(C)CCN(c2ccc(C#N)cn2)CC1 +Nc1ncnn2c(C(O)C3CCOCC3)cc(-c3cc(F)c(CO)c(F)c3)c12 +O=C(NO)c1cc(CS(=O)(=O)c2ccc(Cl)cc2)on1 +O=C(Nc1ccc(Oc2ccnc3ncc(=O)[nH]c23)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1cc(OCCNCCCO)ncc1Cl +Cc1ncnc2c1c1sccc1n2C1OC(CO)C(O)C1O +COc1ccc(C2=[N+]([O-])c3cc([N+](=O)[O-])ccc3C2=O)cc1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCC(O)CO)no2)cc1C#N +CC(Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1)C(F)(F)F +CC(C)CC(NC(=O)c1ccc(N2CCC(CNCC(O)c3ccc(O)c(NS(C)(=O)=O)c3)CC2)cc1)C(=O)O +CCOc1cc(-c2ccccc2)nc2c(F)c(-c3nc(C4CC(C)(O)C4)n4ccnc(N)c34)ccc12 +CN1CCN(C2CC(c3ccc(F)cc3)c3ccc(Cl)cc32)CC12CCCCC2 +CC(C)C(NC(=O)Cn1c(-c2ccccc2Cl)ccc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F +COc1ccc(Cn2cnc(N)c3nc(C(C)(C)O)nc2-3)cc1OC1CCCC1 +NC(=O)C(Cc1ccccc1)NC(=O)C(N)Cc1ccccc1 +COc1ccc(S(=O)(=O)Nc2ccc(-c3cccnc3)c3cccnc23)cc1 +Cc1cc(CNCCCCC(Oc2cc(C)c(F)c(C)c2)C(=O)NO)ccc1F +CCC1CN(c2cccc3cc(S(=O)(=O)Nc4ncns4)ccc23)CCO1 +CCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ccnc(NCC5CC5)c4Cl)C3)cc2)s1 +CSc1ccc(-c2ccc(S(=O)(=O)NC(CC#Cc3ccccc3)C(=O)O)cc2)cc1 +CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(C)nc(C)nc3C)CC2)CC1 +COc1cc2nc(N3CCN(S(=O)(=O)c4no[n+]([O-])c4-c4ccccc4)CC3)nc(N)c2cc1OC +CN1CCN(C2=Nc3ccccc3N(NC(=O)c3ccc(C#N)cc3)c3ccc(Cl)cc32)CC1 +CN(Cc1ccccc1)Cc1ccc(C(=O)c2ccc(OCCCCCCN3CCCCC3)cc2)cc1 +O=C(Nc1cccc(-c2cnc3c(NC(=O)c4ccc(Cl)c(C(F)(F)F)c4)nccn23)c1)Nc1ccc(F)cc1F +CC(C)C1CCCC(COC(=O)N2CCC(N3CCCCC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +N#Cc1cnc(-c2cnc3c(Nc4ccc(C(F)(F)F)cn4)ccnc3n2)c(C(F)(F)F)c1 +C=CC1CC(Cc2ccc(OC)c(O)c2)C2C(=O)C=CC(=C)C12 +Cc1ncnc(N2CCC(CC(=O)NCCN(C)C)CC2)c1C#Cc1ccc(N)nc1 +O=C(c1ccc(Cl)c(Cl)c1)N1CCC(F)(CNCc2cccc(N3CCC3)n2)CC1 +COc1ccc(Cl)cc1NC(=O)Nc1cc(C)nc2ccccc12 +O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1c2c2cccc3c2n1CCNC3 +O=C(c1cnc2ccc(-c3ccc(O)c(Cl)c3)cc2c1NC1CCC(N2CCCC2)CC1)C1CC1 +Cc1cc(-n2nc(Cc3cc(F)cc(C(F)(F)F)c3)nc2C)ccc1C(N)=O +Cc1cc(F)ccc1Nc1nc(N(C)c2ccccc2)c2cccc(OCCCN(C)C)c2n1 +CC(C)CC(NC(=O)COc1c(Cl)cc(Cl)c2ccccc12)C(=O)NC1CC(=O)OC1O +COc1c(Cl)cc(C(C)(C)C)cc1NC(=O)C(=O)c1ccc(OCCN2CCOCC2)c2ccccc12 +CCOc1ccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cc1F +COc1nc(NCCc2ccc(F)cc2)nc(-c2cccc(C(C)=O)c2F)n1 +COc1cc(-c2ccc3ncc(C(=O)C(C)C)c(Nc4ccc(CN(C)C)cc4)c3c2)cc(Cl)c1O +CC(C)(O)C#Cc1cc2c(cc1F)C1CC(C1)n1c-2nc(C(N)=O)c1-c1nc(C2CC2)no1 +O=C(c1cc(-c2cnn[nH]2)ccn1)N1CCc2nc(NC3Cc4ccccc4C3)ncc2C1 +CCCn1c(=O)c2[nH]c(-c3cc(OCC4CC(=O)N(c5ccc(F)cc5)C4)no3)nc2n(CCC)c1=O +COc1cc2ncnc(N3CCN(C(S)=NCc4ccco4)CC3)c2cc1OC +COC(=O)CC1Cc2ccccc2C(CCN2CCCCC2)O1 +Cc1ccc(C(CN2CCC2)N2CCN(c3ncnc(N)c3-c3cn[nH]c3)CC2)c(F)c1F +CC(CSC(CCc1ccccc1[N+](=O)[O-])c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O +CCN(CC)CCOc1ccc(N(C)C(=O)c2ccc(-c3ccccc3)cc2)cc1OC +CC(Nc1nccc(NCCc2ccccc2)n1)c1ccccc1 +Fc1ccc2[nH]c3c(c2c1)CN(CCCc1cccnc1)CC3 +O=C(NCc1ccc(Cl)cc1)c1cn2c(CN3CCCCC3CO)cc3cc(CN4CCOCC4)cc(c1=O)c32 +CCC(CC)CNC(=O)c1cnc(Nc2cccc(Cl)c2)cc1C(C)C +COc1cc(N2Cc3ccc(Sc4ccc(F)c(F)c4)nc3C2=O)ccc1OCCN1CCCC1 +O=C(O)C1=C(C(=O)Nc2c(F)c(F)c(-c3cccc(OC(F)(F)F)c3)c(F)c2F)COC1 +Cc1ccc(C)c(CNC(=O)c2cc(-c3ccc(C)o3)nc(N)n2)n1 +O=C(Cn1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)n1)NCc1ccc(F)cc1 +CC(=O)Nc1ccc(Oc2ccc(C(=O)O)c(C(=O)O)c2)c(NC(=O)c2cccc([N+](=O)[O-])c2)c1 +CCC1=CC2Cc3nc4cccc(F)c4c(N)c3C(C1)C2 +CC12CCC3c4ccc(C(=O)NCCC(=O)O)cc4CCC3C1CC=C2c1cncc(F)c1 +CNc1nc(C#Cc2ccc(Cl)s2)nc2c1ncn2C1C(O)C(O)C2(C(=O)OCCC3CCCCC3)CC12 +CC(C)C12OC1C1OC13C1CCC4=C(COC4=O)C1CC1OC13C2OC(=O)CN1CCCCC1 +Nc1ncnc2c1ncn2C1C(F)=C(CCO)C(O)C1O +CS(=O)(=O)c1cccc2c(CCNCC(O)c3cccc(NS(=O)(=O)c4cc(Cl)c(Cl)s4)c3)c[nH]c12 +COC(=O)c1ccc2c(c1)C(=Cc1ccc[nH]1)C(=O)N2 +OC1COC(n2cnc3c(NCc4cccc(I)c4)ncnc32)C1O +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C(C)CNCc1ccccc1[N+](=O)[O-] 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+Cc1c(C(=O)NCCCCCCCCCN(C)CCCCCCCCCN)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(OCCCCN1CCC(OC(c2ccccc2)c2ccccc2)CC1)c1ccc(Cl)cc1 +O=C1Nc2ccccc2C1=Cc1cc[n+](Cc2ccccc2F)cc1 +Cc1ccc(C(=O)Oc2ccccc2-c2nc3ccccn3c2NC(C)(C)CC(C)(C)C)cc1[N+](=O)[O-] +COc1ccc(C2(C(F)(F)F)CC(c3ccc(C)cc3)=C(C(=O)Nc3ccc(F)cc3)C(=O)N2)cc1 +COc1ccccc1CNCCCCCCNCCSSCCNCCCCCCNCc1ccccc1OC +Cc1ccc(C2=C(C(=O)NC3CC3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +C=CCc1cc(O)cc2nc(-c3ccc(O)cc3F)oc12 +CC(C)(N)COC(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CCN1CCN(Cc2cc(-c3cnn4c(-c5cccc(NC(=O)c6cccc(C(F)(F)F)c6)c5)ccnc34)co2)CC1 +C=CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(Cc1ccccc1)CC2 +COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(C(C)(C)S(C)(=O)=O)cc2)CC3)cc1 +Cc1ccc(C(=O)Nc2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cnc(N3CCC(F)C3)nc12 +CCCCCNC(=O)Nc1ccccc1OCCCn1cnc(-c2ccccc2)c1C +COc1ccc(C#CC=CC#Cc2cc(OC)c(OC)c(OC)c2)c([N+](=O)[O-])c1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)n2)cc1CN1CCC(C(=O)NC(C)(C)C)CC1 +COCCCCC(CO[N+](=O)[O-])O[N+](=O)[O-] +CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(C(Oc2ccccc2C(F)(F)F)c2ccc(C(F)(F)F)cc2)CC1 +O=C1OC2CCCCC2N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1 +CCCn1c(=O)c2nc(-c3ccc(S(=O)(=O)O)cc3)[nH]c2n(CCC)c1=O +Cc1ccc(-c2cc(CCC(=O)N3CCN(Cc4ccc(C(C)(C)C)cc4)CC3)nn2-c2ccc3ccccc3n2)cc1 +COCCOC(=O)Nc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 +COc1ccccc1CS(=O)(=O)C(C)(C)C(N)C(=O)N1CC(F)CC1C#N +NCCCCn1c(SCCc2c[nH]c3cc(F)ccc23)nnc1-c1ccc2ccccc2n1 +CC(Nc1ccccc1)c1ccc(C(C)Nc2ccccc2)cc1 +CNc1nc(NCc2ccc(Cl)cc2)cc(-c2ccccn2)n1 +CC(NC(=O)Nc1cc2[nH]nc(C3CC3)c2cn1)c1ccccn1 +COc1cc2c(NC3=CC(=O)C(OCC#Cc4ccccc4)=CC3=O)ncnc2cc1OCCCN1CCCC1 +COC(=O)c1cccc2c1CCN(c1nc(-c3ccc(C(C)(C)O)nc3)cc3ncn(C)c(=O)c13)C2 +CC(C)CC(C(=O)NCC(=O)CNS(=O)(=O)c1ccc(Oc2ccccc2)cc1)c1cccc(-c2ccccc2)c1 +Cc1ccccc1S(=O)(=O)c1c(C(=O)NCCO)[nH]c2ccc(Cl)cc12 +CN1CCC(n2c(=O)n(C)c3cnc4ccc(-c5ccc(N(C)C)nc5)nc4c32)CC1 +CCCn1c(=O)c2[nH]c(-c3cc(=O)[nH]n3C)cc2n(CCC)c1=O +Cc1ccc2c(-c3nnc(SCCCCN4CCc5cc6nc(C)oc6c(Br)c5CC4)n3C)cccc2n1 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+CNc1nc(Nc2ccc(C#N)cc2)nc(Oc2ccc(Cl)c3ccccc23)n1 +O=C(NCCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1)c1ccccc1 +COC(=O)C(C(=O)OC1CC2C3OC3C(C1)[N+]2(C)C)(c1ccccc1)C1CCCC1 +CN(C)CCCn1c(NC(=O)c2ccc3cc4n(c3c2)C(C)(C)CNC4=O)nc2ccccc21 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccccc3)oc2c1 +CN1C(=O)CCc2cc(-c3cncc4c3CCCC4NC(=O)C3CC3)ccc21 +CN(CCC(N)CC(=O)NC1C=CC(n2ccc(N)nc2=O)OC1C(=O)O)C(=N)N +O=C(NC1CCCCC1O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 +CCCN(CCN1CCN(c2ccc(-c3cccc(O)c3)cc2)CC1)C1CCc2c(O)cccc2C1 +Cc1nnc(S(=O)(=O)CC(=O)C23CC4CC(CC(C4)C2)C3)s1 +CSc1ccccc1N1CCN(CCCCCC(=O)N2CCCC2C(N)=O)CC1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCc3ccccc3)c2)n1C +COc1ccc(Nc2ncc(CN3CCN(S(C)(=O)=O)CC3)cc2-c2nc(C)nc(N)n2)cn1 +COc1ccnc(N2CC3CN(C(=O)c4cccc5ccccc45)CC3C2)n1 +O=C(Nc1cccc(F)c1)c1ccc(N2CCCC2)c(C(F)(F)F)c1 +c1ccc2c(c1)CC(CN1CCN(c3ccc4c(c3)OCCO4)CC1)C2 +Cc1nsc(N2CCC(N3CCC3C(=O)N3CC(S(=O)(=O)c4ccccc4Cl)CC3C(=O)NC3(C#N)CC3)CC2)n1 +Cc1cccc(-c2nn(CCC(=O)Nc3cccc(C#N)c3)cc2-c2ccc3ncccc3c2)n1 +CC(C)(C)c1cc(-c2nnc(NC#N)o2)cc(C(C)(C)C)c1O +Cn1c(SCCCN2CC3CCN(c4ccccc4C(F)(F)F)C3C2)nnc1-c1cnccn1 +O=C(Nc1cnc(C(=O)NO)c(O)c1CO)c1ccc(F)cc1 +O=C(Nc1cccc(C#Cc2ccc3nccn3n2)c1)c1ccccc1 +COc1cc2c(cc1OC)CC(CC1CCN(CCNc3c4c(nc5cc(Cl)ccc35)CC3C=C(C)CC4C3)CC1)C2 +Cn1ccnc1S(=O)(=O)Cc1cccc(C(c2c(O)cc(C(CC3CC3)CC3CC3)oc2=O)C2CC2)c1 +Clc1ccc2[nH]c(-c3cc4ccc(Br)cc4[nH]3)cc2c1 +COc1cc(NCc2cnc3nc(N)nc(N)c3c2C)c(O)cc1-n1cccc1 +O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccc(Cl)cc3F)CCC2)c1 +Nc1ncc(-c2ncnc3[nH]cc(F)c23)nc1C(=O)Nc1ncccc1N1CCC(N)CC1 +O=C(O)C(Sc1nc(Cl)cc(Nc2cccc(Cl)c2)n1)c1cccc2ccccc12 +CC(C)CC(NC(=O)C(Cc1ccccn1)NS(=O)(=O)c1cccc2cccnc12)B(O)O +COC(=O)c1cc(CNC(=O)c2ccc(-c3cn[nH]c3)c(OC)c2)ccc1F +CC1=CC(=O)OCC23CC(O)C(C)=CC2OC2CC(OC(=O)C=CC=CC(=O)OCC1)C3(C)C21CO1 +CCNc1ccc(C(=O)N2CCCCc3ccccc32)c(Cl)c1 +COc1ccc2c(c1)C(=Cc1ccc(OC)c(OC)c1)C(=O)CC2 +COc1ccc(C=C(C(=O)c2ccc(Cl)cc2)C(=O)C(F)(F)F)cc1OC +CC(C)CC(C(=O)NCC#N)c1cccc(-c2ccc(C3COCCN3)cc2)c1 +COC(=O)c1nnn2c1CN(C(=O)CC(N)Cc1cc(F)c(F)cc1F)CC2 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+O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1ncccc1O +Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)C1=C(Cl)C=C(CCCN2CCCNCC2)CC1Cl +Oc1nc2c(-c3cccc(Br)c3)nnn2c2ccccc12 +Cn1c(=O)c(S(=O)(=O)c2ccc(Cl)cc2)cc2cnc(Nc3ccc4[nH]ccc4c3)nc21 +CCCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 +N#Cc1ccccc1-c1cccc(-c2cnc3nc(C(F)(F)F)ccn23)c1F +CCc1ccc(Oc2ccc(C(=O)NCCOCC(=O)NCC(=O)OC)cc2)cc1 +CC(C)C(O)CCC(C)C1CCC2C3CC=C4CC(O)CCC4(C)C3CCC12C +O=C(NCCN1CCC(C(=O)c2ccc(F)cc2)CC1)c1nsc2ccccc12 +Cc1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)CCO)sc2ccccc12 +COc1ccc2[nH]c(C)c(CC(=O)NC(CCCCNS(N)(=O)=O)C(=O)Nc3nc(-c4ccccc4)cs3)c2c1 +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc(C(F)(F)F)c2)[nH]c1=O +O=C(OC1CNC(C#Cc2cc3ncnc(NCc4cccc(Oc5ccccc5)c4)c3s2)C1)N1CCOCC1 +CC1CCC(Oc2cc(C#N)ccn2)CN1C(=O)c1cc(C(N)=O)ccc1-n1nccn1 +O=C(Nc1ccc(Oc2ccccc2)cc1)NC(CN1CCCC1)c1ccccc1 +CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc32)ccc1OC(C(=O)O)c1ccc2c(c1)OCO2 +O=C1Nc2ccc(Cl)cc2C(CNC(=O)c2cccc(F)c2)(C(F)(F)F)O1 +Cn1c(-c2cccc(C=CC(=O)NO)c2)nc2ccccc21 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+COc1cc(C=CC(=O)OCCSc2nc(-c3ccc(S(C)(=O)=O)cc3)n(-c3ccccc3)n2)ccc1O +CN1Cc2cc(C(=O)N(Cc3nc4ccccc4[nH]3)C3CCCCC3)ccc2NC(CC(=O)O)C1=O +COC(=O)C1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCCCO2 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(CNc1ccc(N2CCOCC2)cc1)Cc1ccccc1 +CN(CCCl)CCNN=Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1 +CCN(CC)CCNc1cc(-c2ccc(F)cc2)c(C#N)c2nc3ccccc3n12 +Cc1cc(Cl)cc(C)c1OCc1noc(C(C)C)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +Cc1ccc(C(=O)NCc2ccc(C(F)(F)F)cc2)cc1Nc1ncnc2cnc(N3CCCC3)nc12 +CN(C)CCNc1nc2c3c(cccc3n1)C(=O)c1ccccc1-2 +CN(Cc1ccccc1)Cc1ccn(-c2cc3c(cc2[N+](=O)[O-])[nH]c(=O)c(=O)n3CCC(=O)O)c1 +O=C(c1ccc2[nH]ccc2c1)N1CCCC2c3ccccc3CCC21 +N#Cc1cnn2ccc(NC(=O)CCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc12 +CC(C)=CCn1cc2c(nc(NC(=O)Nc3cccc(Cl)c3)n3nc(-c4ccco4)nc23)n1 +CCc1nc2n(c1C(=O)N(CC)CC1CC1)CCN2c1c(C)cc(C)cc1C +O=P(O)(O)OC1C(O)C(O)C(OP(=O)(O)O)C(OP(=O)(O)O)C1F +CN1C(=O)c2ccccc2C1C(=O)NCc1ccc(Cl)cc1Cl +CN1C(=O)NCc2c(NC(=O)NC3CCOc4cc(F)ccc43)cccc21 +CC(=O)c1ccc(OCc2ccccc2)cc1OC(CCC(=O)O)c1ccccc1 +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3CCCS3(=O)=O)cc2n1 +Cn1ncc(NC(=O)c2csc(-n3ncc4ccccc43)n2)c1C1CCC(N)C(F)CO1 +NCCNC(=O)NC(=O)C1CCCN1C(=O)C(CC1CCCC1)CN(O)C=O +CCN(CC)CCCCCCCNc1ccc2c3c(nn2CCN(CC)CC)-c2ccccc2C(=O)c13 +COc1cc2c(cc1OC)C(=O)N1C=C(c3cccc(C)c3)CC1C=N2 +COc1ccc(-c2cc(-c3c(C)oc4c(OC)c5occc5c(OC)c4c3=O)[nH]c(=N)c2C#N)cc1OC +Cc1ccncc1-c1cc(F)c2c(c1)CCc1nnc(C)n1-2 +CC1(C)CC(O)(C(F)(F)F)C(Nc2cccc3[nH]c(=O)ccc23)c2ccc(F)c(O)c21 +Cc1ccc(-n2nccn2)c(C(=O)N2CCOCC2Cc2cccc(-n3cncn3)c2)c1 +c1ccc(C(OCCN2CCN(CCOC(c3ccccc3)c3ccccc3)CC2)c2ccccc2)cc1 +ClCCN(CCCl)CCCCOc1ccc(Nc2c3ccccc3nc3c(OCCN(CCCl)CCCl)cccc23)cc1 +COC(=O)C(C)NP(=O)(OCC1C=CC(n2cc(C)c(=O)[nH]c2=O)O1)Oc1cccc(Cl)c1 +CCc1nnc(C(Cc2ccccc2)NS(=O)(=O)c2ccc(Cl)cc2)n1C +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2cccc(=O)[nH]2)cn1C(C)C +CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cccc1OC +CCc1nc(-c2ncn3c2CN=C(c2ccccc2)c2c(F)cccc2-3)no1 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccc3c(c2)CCCC3)c1)C(F)(F)F +CC(=O)Nc1ccc(C#Cc2ccc(NC(C)=O)cc2)cc1 +CCc1c(-c2nnc(C3(c4ccc(C)cc4)CC3)s2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1 +O=C(C(=Cc1ccc(F)cc1)Oc1ccc(C=NNc2ccnc3cc(Cl)ccc23)cc1)c1ccc(Cl)cc1 +CN(C)CCCCN1CCN(CCCCCCCCCOc2ccccc2)CC1 +Cc1c(Nc2c(C#N)cncc2C=Cc2ccc(CN3CCC(N(C)C)CC3)cn2)ccc2[nH]ccc12 +Cc1cccc(C(=O)N2C(C)COCC2Cc2cccc(-n3nccn3)c2)c1-n1nccn1 +Cc1cc(CCC(=O)c2sc(C)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNCCC(=O)O +COc1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)cc1)C2O +c1ccc(CNCC2CCC3(CC2)OOC2(CCCCC2)OO3)cc1 +CN(C)c1ccc(C(=O)NCCCCCCNc2c3c(nc4ccccc24)CCCC3)cc1 +N#CNC(N)=Nc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1cccc(Cl)c1)CC2 +O=C(NO)c1ccc(CNC(=O)c2[nH]c(-c3ccccc3)cc2-c2ccc(F)c(F)c2)cc1 +CC(C)(CO)CNc1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +CCCC(=O)Nc1ccc2nc(C=CC3C4CCCCC4CC4C(=O)OC(C)C43)ccc2c1 +COc1cc(NC(=O)Nc2ccncc2)cc(-c2cccnc2)c1OC +Cc1nnc(Cl)c2nn(-c3cccc(Cl)c3)c(C)c12 +O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(C4(O)CCC4)c(F)c3)cc12 +CN(C)CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1F)c1cccc(C(=N)N)c1 +Cc1ccc(N(C(=O)c2cccs2)C(=S)OCCN2C(=O)c3ccccc3C2=O)cc1 +COC(=O)c1ccc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)n2c1 +CCc1nn(C2CCCC2)c2c1CCn1c(-c3ccccn3)nnc1-2 +O=C(CCCCCCc1ccccc1)c1nc(-c2cccs2)no1 +CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(F)cccc3C(F)(F)F)CC2)CC1 +CC(C)(C(=O)Nc1nccs1)C(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C1CCCC1 +CC(=O)c1ccc(C(C)=O)c2c(C)c(C(=O)Nc3cc(C)c4ccccc4n3)sc12 +N#CC(=C1Nc2ccccc2S1)c1ccnc(NCCCN2CCOCC2)n1 +CC(C)n1ncc2c(NC(=O)NCc3ccc(C(F)(F)F)cc3CCC(C)(C)C)cccc21 +Cc1cc(C(N)=O)ccc1-n1c(Cc2nnn[nH]2)ccc1-c1ccc(Br)cc1 +Cc1ccc2nc(SCC(=O)Nc3ccc(S(N)(=O)=O)cc3)n(Cc3ccccc3)c(=S)c2c1 +COc1cc(N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccc(N3CCOCC3)cc2OC)n1 +COc1cc(Oc2c(C)cc(C)cc2C)cc(Nc2ccc(C#N)cc2)n1 +O=C1C(=O)N(Cc2ccccc2)C(=O)c2ccccc21 +O=C(O)CCCCCCCCCCCNC(=O)Nc1ccc2ccccc2c1 +CCC(CC)C(NS(=O)(=O)c1ccc(Cl)s1)c1ccnn1-c1ccc(OC)cc1 +CCOC(=O)c1cnn(CC(O)CC)c1NC(=O)Nc1ccc(F)cc1 +Cc1ccc2c(c1)Oc1ccccc1C(N1CCN(C)CC1)=N2 +COc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N(C)C)cc4c3)n2)c1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)c1cn(CCO)cc(-c2ccc(F)cc2)c1=O +COc1cc(OC)cc(N2CCN(C(=O)c3onc(C)c3-c3ccc(F)cc3)CC2)c1 +COc1ccc2c(c1)C(=NNC(=O)c1cnn(-c3ccc(S(N)(=O)=O)cc3)c1-c1ccccc1)C(=O)N2 +CCCCCC12CCC(COc3cc(F)c(C(=O)NS(=O)(=O)N(C)C)cc3Cl)(CC1)CC2 +CC1CCN(C(=O)c2ccc3nc[nH]c3c2)C2Cc3ccccc3C12 +COC(=O)c1cccc(-c2cnc(C(=O)C3COc4cc(Oc5ccccc5)ccc4C3)o2)n1 +O=C(O)CCCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O +C=CC=CC(C)C1OC(=O)C=CC=CC(C)C(O)CC(O)CCC(C)C(O)C(C)CC(C)CCC(O)C1C +CC(C)Oc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3ccccc31)CC2 +Cc1nc(N2CC3CN(C(=O)c4ccccc4-n4nccn4)CC3C2)ncc1F +Cc1c(O)cccc1C(=O)NC(Cc1ccccc1)C(O)C(=O)N1CSCC1C(=O)NC(C)(C)C +CS(=O)(=O)N1CCc2[nH]nc(C(=O)N3CCC(c4cccc(F)c4Cl)CC3)c2C1 +O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(c1)CCN2C1CN(CCF)C1 +COc1ccc(C2(c3ccc(OC)cc3)C(c3ccccc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1 +CC(C)CC(NC(=O)c1cnccn1)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1 +O=C(CN1CCN(c2ccnc(NCCc3ccc(Cl)cc3)n2)CC1)N(Cc1ccccc1)Cc1ccncc1 +CCC1CCCC(C2(OC(=O)N3CCC(N4CCCCC4)CC3)CC2)N1S(=O)(=O)c1ccc(F)c(F)c1 +CN1CCc2c([nH]c3ccccc23)Cc2[nH]c3ccccc3c2CC1 +O=C(c1ccc(C(=O)N2CCCC3CCCCC32)cc1)N1CCCc2ccccc21 +Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)n1C1CCCCC1 +Cc1cnc(NC(=O)c2cc(Sc3nncn3C)ccc2N)s1 +CCN1CCCC(n2c(-c3cccc(C=CC(=O)NO)c3)nc(C)c2-c2ccccc2)C1 +CNS(=O)(=O)c1ccc(NC(=O)Nc2ncccc2OCc2ccccc2)cc1 +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(C(C)=O)cn3)CC2)CC1c1ccc(Cl)cc1 +O=C(O)Cn1c(=O)c(-c2ccc(O)cc2O)nc2ccc(Br)cc21 +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(N3CC4C5CCC(C)(O5)C4C3)c2cn1)c1ccc(F)cc1 +CCCS(=O)(=O)Nc1ccc(F)c(-c2cc3cnccc3cn2)c1F +O=C(NCCc1ccc(OCCN2CCCC2)c(Br)c1)c1cccc(C(F)(F)F)n1 +COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2S(=O)(=O)C(C)C)n1 +CC(O)c1nc2cnc3[nH]ccc3c2n1C1CCC(CCC#N)CC1 +O=C(Cc1ccc(C(F)(F)F)cc1C(F)(F)F)NC1N=C(C2CC2)c2ccccc2N(CC(F)(F)F)C1=O +CCc1nc2c(C)cc(C)nc2n1Cc1ccc2c(c1)CCN2C(C(=O)OC)c1ccccc1 +COCC(NC(=O)Nc1cc2[nH]nc(Nc3ccccc3)c2cn1)c1ccc(F)cc1 +CCc1csc(C(Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)CNC(=O)OC)n1 +O=C(CCc1ccc(OCc2ccccc2)cc1)c1nc2ncccc2o1 +COc1cc(Cn2c(CCc3ccccc3)nc3cc(CCC(=O)NO)ccc32)cc(OC)c1OC +C=CC(=O)Nc1ccccc1Nc1ncc2cc(-c3c(Cl)c(OC)cc(OC)c3Cl)ccc2n1 +O=C(Nc1nc(-c2ccccc2)cs1)C1CCCCN1C(=O)N1CCS(=O)(=O)CC1 +Cc1noc(C)c1C(=O)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CCCCc1nc(CN2CCN(c3ccccn3)CC2)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +N#Cc1cc(NCCCn2ccnc2)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +COCc1cccc(-c2cnc3ccc(NC(=O)NC(C)CCCc4ccccc4)nc3n2)c1 +CCCC(NC(=O)C1(NC(=O)c2ccc(OC(F)(F)F)cc2)CCCCC1)C(=O)c1nnc(-c2ccccc2)o1 +O=C1NC(=O)C2(CCN(CCC3CC(=O)c4ccccc4C3)CC2)N1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(O)(CNC(=O)Cc1ccccn1)C2 +O=C(OC1CCN(Cc2ccc(F)cc2)C1)C(O)(c1ccccc1)c1ccccc1 +Cc1cn(-c2ccc3n(c2=O)CCN(C(C)C2CCC(c4ccc(C(F)(F)F)cc4Cl)O2)C3=O)cn1 +CC1=NN(c2nnn[nH]2)C(=O)C1=Cc1cc(Cl)c(O)c(Cl)c1 +FC(F)(F)c1cc(COCC2(c3ccccc3)CCN(Cc3ncon3)CC2)cc(C(F)(F)F)c1 +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3cccc4[nH]cc(C)c34)nc(N3CCCC(O)C3)c2C1 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+CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)C4CCCN4CC(C)C)ncn3)cccc2s1 +CC(C1C(O)CC2(C)C3CCC4C5(C)COC(C(C)(C)F)=NC5CCC45CC35C(=O)CC12C)N(C)C +CS(=O)(=O)C1CCc2c(c(-c3ccc(C(F)(F)F)c(SCCO)c3)nn2CCCN2CCC(N3CCCC3=O)CC2)C1 +Cc1cnccc1N1CCN(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CC1 +O=C(NC1CCNC1)c1ccc2[nH]c(-c3cc4ccccc4nc3O)cc2c1 +Cc1cccnc1C1CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +N=C(N)c1cccc(Oc2ccc(N)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +O=C(O)C=NOC(c1ccc(OCc2nc(-c3ccccc3)cs2)cc1)C1CCCCC1 +COc1cc(-c2cc3cc(C(C)N(O)C(C)=O)ccc3o2)cc(OC)c1OC +CCn1c(C=CC=C2N(C)c3ccccc3C2(C)C)[n+](CCCOC(C)=O)c2nc3ccccc3nc21 +COc1cc(OC)c2c(C(=O)C=C(O)C(=O)O)cn(Cc3ccc(F)cc3)c2c1 +Cc1nc(NC2CCCc3ccccc32)cc(-c2ccc3ncsc3c2)n1 +CCNCCNc1cc(-c2ccc(C(F)(F)F)cc2)c(C#N)c2nc3cccc(Cl)c3n12 +CCNc1ncc(C(=O)OCC)c2nc(-c3ccco3)nn12 +CC(C)c1ccc(-n2ncc(Cl)c(Oc3ccc(CO)cc3)c2=O)cc1 +CC(=O)c1ccc(-c2ccc(C(=O)NCCCCN3CCc4ccc(OS(=O)(=O)C(F)(F)F)cc4C3)cc2)cc1 +Cc1ccc2c(N3CCN(CCc4cc(F)c5c(c4)NC(=O)CO5)CC3)cccc2n1 +COc1ccc(-c2noc(CSc3nnc(C)n3-c3cccc(C)c3)n2)cc1 +CS(=O)(=O)c1ccc2c(c1)CCC1(CCCN(C(=O)NC3CC3c3ccccc3)CC1)O2 +CC(C)(CNc1nc(NCCO)nc(Nc2cccc(N)c2)n1)CNc1nc(NCCO)nc(Nc2cccc(N)c2)n1 +Cc1cc(C(N)=O)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(Cl)cc1NC=O +CN(C)CCCN1CCCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)C1 +CCCCCCc1nccn1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +CC(C)CNC(=O)c1cc(-c2cc(F)c(Cl)cc2Cl)n[nH]1 +NC1CCN(C2CCC3(CC2)OOC2(OO3)C3CC4CC(C3)CC2C4)CC1 +COc1ccc(C2=NN(CCNCC(O)c3ccc(O)c(NC=O)c3)C(=O)C3CCCCC23)cc1OC +CCn1cc(-c2cc3c(-c4cc(C#N)cc(N5CCCNCC5)n4)n[nH]c3cn2)cn1 +CC1(C)OC(c2ccnc(N)n2)=C(c2cc(Cl)cc(NS(=O)(=O)c3ccc(F)cc3F)c2F)C1=O +c1ccc2c(c1)NC1CCCCC1=C2NCCCCCCCCNC1CCNC2CCCCC21 +Cc1cccc(C(=O)NC(CC(=O)O)C(=O)CF)c1NC(=O)OCc1ccccc1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4ccc(C(F)(F)F)cn4)CC3)CN(C)C1C2 +N#CC1CC(F)CN1C(=O)CNCCNc1ccc(C(N)=O)cn1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1ccc(F)cc1 +CCCC1(C2CCCC2)Cc2cc(OCCCC(=O)O)c(Cl)c(Cl)c2C1=O +COc1nccc2[nH]nc(-c3cc(C(=O)N(C)C)n(C(C)C)c3)c12 +O=c1c(-c2ccc(F)cc2)c(-c2ccnc(NCc3ccccn3)n2)n2n1CCC2 +Cc1cc(N)nc(CCc2cc(N)cc(CCc3cc(C)cc(N)n3)c2)c1 +NC(=O)c1ccc(NC(=O)c2ccc(-n3ccccc3=O)cc2)c(NC(=O)c2ccc(Br)cc2)c1 +CC(NC(=O)c1cccn1C(C)C)c1c(F)cccc1Cl +CC(C)COc1ccc(S(C)(=O)=O)cc1-c1cn(C)c(=O)c2[nH]ccc12 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc(OC(F)(F)F)cc4)cc3F)ccnc2cc1OCCCN1CCCCC1 +Nc1ncc(CNC(=O)Nc2ccc(S(=O)(=O)c3ccccc3)cc2)cn1 +Cc1ccc(F)cc1C1CC(=NN=C(N)N)c2ccccc2C1 +CCOc1ccc(C(C)=O)cc1NC(=O)c1cc(COC2CCCCO2)cc(C(=O)O)c1 +CCN(CC)CCNC(=O)c1ccc(-c2cnc(N)c(SC(C)c3c(Cl)ccc(F)c3Cl)c2)cc1 +CN(CC=Cc1ccc(Br)cc1)Cc1cccc2cc[nH]c12 +COC(=O)C1(CNC(=O)c2cc(Cl)cc(Cl)c2)CCN(Cc2ccc(C(F)(F)F)cc2)CC1 +Nc1ncnc2c1ncn2C1OC(CNC(=O)COC2=C(c3cccc(Cl)c3)C(=O)OC2)C(O)C1O +CCOc1cc(CN2CCC(NC(=O)c3cncc(C)c3)CC2)cc(OCC)c1-c1ccccc1 +C=CCN(c1cccnc1)C1CCN(CC2CN(C(=O)C3CCCCC3)CC2c2ccccc2)CC1 +Cc1ncc(OCC2(c3ccccc3)CC2C(=O)Nc2ccccn2)c(C)n1 +Cc1cc(C)n(CC(=O)N2CCN(c3scnc3-c3nc4ccccc4[nH]3)CC2)n1 +O=C(O)CCc1ccc(OC2CCN(C(=O)NC3C(c4ccc(F)cc4)C3c3ccc(F)cc3)CC2)cc1 +Cn1cc2cc(-c3n[nH]c4ccc(C(=O)NC5CC(C(F)(F)F)CN(Cc6c(F)cccc6F)C5)cc34)ccc2n1 +c1ccc(Oc2ccc3c(NCCCNCc4ccco4)ccnc3c2)cc1 +Cc1ncc2ccc(Oc3c(C)ccc(C(=O)c4c(-c5ccccc5)n(C)n(-c5ccccc5)c4=O)c3N)cc2n1 +C=CC(=O)Nc1ccc(OC)c(Nc2cc(-c3[nH]c(SC)nc3-c3ccc4ccccc4c3)ccn2)c1 +CC(C)Cc1sc(-c2nccs2)nc1C(=O)NCCCCCC(=O)NO +CCCCCCCCCCCOc1ccccc1CCC(=O)OCc1ccccc1OP(=O)(O)OCC(N)C(=O)O +CC(c1ccccn1)c1c(CCN2CCC2)sc2ccccc12 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)c(-c3ccc(Cl)cc3)cc21 +Nc1nc(=O)c2c(CCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)c[nH]c2[nH]1 +C#CCC1CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 +CC(C)n1c(CNC2CCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CN1CN(c2ccccc2)C2(CCN(Cc3csc4ccccc34)CC2)C1=O +COc1ccc(-c2c(O)nc3cc(Cl)c([N+](=O)[O-])cc3c2OCCC2CCCCN2)cc1OC +CC(=O)Nc1nc(C)c(-c2csc(Nc3cccnc3)n2)s1 +CN1C(=O)CN=C(c2ccccc2)c2cc(Cl)c(Cl)cc21 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(N)C5)cn3)n2)s1 +O=C(O)CCCCC=C(c1cccnc1)c1cccc(Br)c1 +O=C1c2c(c(-c3c(F)cccc3F)c3cccnc3c2O)CN1Cc1ccc(F)cc1 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+O=C(Cc1ccccc1)NC(NC(=O)Cc1ccccc1)c1ccc(N2CCCCC2)cc1 +COC(=O)C(C)NC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)C(NC(=O)CC(C)C)C(C)C)C(C)C +CCc1cc(C)c(-c2nnc(CCOC)[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +O=C(c1ccccc1)N1CC2CC34CCC1C2C31CCN(CC2CC2)C4Cc2ccc(O)cc21 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cnn(-c2ccc(C(F)(F)F)cc2)n1 +O=S(=O)(c1cccc(F)c1)c1cn(CCN2CCCC2)c2ncccc12 +CC1(CF)C=C(C(S)=NCCC#N)c2cc([N+](=O)[O-])ccc2O1 +COCC1OC(=O)c2coc3c2C1(C)C1=CCC2(C)C(=O)CCC2C1C3=O +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)NNC(=O)C(N)=O)cccc2-3)cc1 +CC1COCCN1c1nc(-c2ccc(Nc3nn(C)c(=O)[nH]3)cc2)nc2c1CCN(c1ncccn1)C2 +COc1ccc(C2C(=O)N(c3cc(OC)c(OC)c(OC)c3)C2c2ccc(OC)cc2)cc1 +COc1ccc(C(C(=O)NCCCN2C(C)CCCC2C)c2ccc(OC)c3ccccc23)c2ccccc12 +CN(CCOc1ccc(CC(Nc2ccccc2Oc2ccccc2)C(=O)O)cc1)c1nc2ccccc2o1 +O=C(Cc1ccccc1)Nc1nonc1NC(=O)c1ccccc1 +CSc1cc(NC(=O)CCC2OC3OC4(C)CCC5C(C)CCC(C2C)C35OO4)cc(SC)c1 +CSc1ccccc1C(=O)C1CCCN(Cc2cnn(-c3ccccc3)c2)C1 +CCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2C)c(F)c1 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+O=c1c2c(oc(O)c1C(c1cccc(NS(=O)(=O)c3ccc(OC(F)(F)F)cc3)c1)C1CC1)CCCCCC2 +CNc1nc(Nc2cnn3c2C(C)N(C)CC3)ncc1C(F)(F)F +CCCCN(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)C(CC(=O)O)c1ccc(Cl)c(F)c1 +CCOC(=O)CN(C(=O)C(CC(=O)NCC1CCCN(C(=N)N)C1)NS(=O)(=O)c1ccc2ccccc2c1)C1CC1 +N=C(Nc1cccc(C2(O)CCN(CCc3cccc(Cl)c3)CC2)c1)c1cccs1 +NC(=O)c1ccc2c(c1)N=C(C=Cc1ccccc1)N(C1CC1)C2 +Cn1c(C(N)=O)cc2c(-c3ccc(NC(=O)C4CCCN4C(=O)OC(C)(C)C)cc3)ncnc21 +CC1CCCN1CCc1ccc(C2=CCC3CN(C(=O)c4cccnc4)CC23)cc1 +CCCCCCCCCCc1cc(NC(=O)Nc2c(C(C)C)cccc2C(C)C)on1 +CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CC4CCNC4C3)c2c1Cl +N#Cc1c(N2CCC(c3cccc(C(F)(F)F)c3)CC2)ccn(CC2CC2)c1=O +COc1ccc(S(=O)(=O)N(Cc2ccc(F)cc2)CC2CCC(C(=O)O)CC2)cc1 +CNC(CC(C)C)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1 +CC(C)(CNC(=O)C1(C#N)CCOCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +Cc1ccc(NCc2ccc(-c3ccc(F)cc3)nc2)cc1 +CCOC(=O)C(Cc1ccccc1)Nc1nc2ccccc2o1 +O=C(Nc1ccc(F)cc1)c1ccc(SCc2ccccc2O)nc1 +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(C5CCN(C)CC5)cc4)c3)c(OC)cc21 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+CC(F)(F)c1cccc(N2C(=O)CN(c3cccc(C(F)(F)F)c3)CC2C(=O)NC2CCCC2)c1 +CC1CCN(C(=O)N2CCCC2)CC1N(C)c1ncnc2[nH]ccc12 +COc1ccccc1N1CCN(CCn2c(C)nc3c(sc4ccccc43)c2=O)CC1 +CN(C)C(=O)n1nnnc1CNC(=O)c1cccc(-c2ccccc2)c1 +COc1ccccc1C1CCN(c2[nH]c(=O)[nH]c(=O)c2Cc2ccccc2)CC1 +Cc1cccc(C(=O)c2nccc3c2[nH]c2ccccc23)c1 +O=C(NO)c1cc2ccn(Cc3ccc(F)cc3)c2cn1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C4CC4)nn3)c2)c2cncnc21 +O=C(NCc1ccc(S(=O)(=O)c2cnc(N3CCOCC3)nc2)cn1)c1ccc2nccn2c1 +Cc1cc(C(=O)Nc2ccc(C(F)(F)F)cc2)ccc1-c1ncccc1C(F)(F)F +Cc1ccc(C(=O)N2CCC3(CC2)OCc2cc(C#N)ccc23)cc1NC(=O)c1ccc(N2CCCC2)nc1 +CCOC(=O)N1CCC(Nc2ncc3c(n2)-c2c(c(C(=O)NC)cn2C)CC3)CC1 +NS(=O)(=O)c1ccccc1-c1ccc(C(=O)NCCC(=O)Nc2ccc(Br)cc2)cc1 +CN(C)CCn1cnc(-c2ccc(F)cc2)c1-c1ccc2[nH]ncc2c1 +Cc1nnc(C(C)C)n1C1CCN(C(C)CC(NC(=O)C2CCOCC2)c2ccccc2)CC1 +CC(C)Oc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCN(C)C)CC1 +COc1nn(C)c2ncnc(NS(=O)(=O)c3cccc(Cl)c3Cl)c12 +CCCCNC(=O)Oc1ccc2c(c1Br)c1c(n2C)C(=NC)CC1 +CCN(CC)CCNC(=O)c1nn(-c2ccc(C)cc2)c(=O)c2c1c1ccccc1n2C +Nc1ncc(-c2cc(N3CC(N4CCC(F)(F)CC4)C3)nc(N3CCC(F)(F)C3)n2)cc1OC(F)F +COc1cc(C(=O)N2CCC2c2noc(-c3ccccc3OC(F)(F)F)n2)c(-n2nccn2)cc1F +CCc1cc(OCCc2ccc(C(=N)N)c(O)c2)cc(OS(=O)(=O)c2cc(Cl)cc(Cl)c2OC)c1 +N#Cc1cc(Cl)cc(Oc2c(Cl)ccc(CNC(=O)c3[nH]c(CO)nc3Cl)c2F)c1 +Cc1nn(CCO)c(C)c1CC(=O)NCc1cccc(Cl)c1C +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5cccc(OC)c5)C4)c3)nc2n(CCC)c1=O +CC(=O)Nc1ccc(-c2csc(-c3ccc(S(=O)(=O)Nc4ccc(CCNCC(O)c5cccnc5)cc4)cc3)n2)cc1 +Cc1ccc(C(=O)NC2CC2)cc1-c1cc2nnc(-c3c(F)cccc3Cl)n2n(C)c1=O +O=C1CCC(C(=O)NC(CCCCCS)C(=O)Nc2cccc(C(F)(F)F)c2)N1 +COC(=O)NC1(c2ccc(N3CCc4c(C(F)(F)F)nn(-c5ccc(OC)cc5)c4C3=O)cc2)CC1 +Cc1cc(OCc2ccccc2)cc(C)c1-c1cccc(COc2ccc(CCC(=O)O)cc2)c1 +COc1c(OCC(O)CN2CCCCC2)ccc2c1N=C(NC(=O)c1cncs1)N1CCN=C21 +CS(=O)(=O)Nc1ccc(S(=O)(=O)N(CCC2CC2)c2sc3ccccc3c2Cl)cc1 +CCCCc1cn(-c2c(C(C)C)cccc2C(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1 +CCC(NC(=O)c1cc(C(=O)NC(C)c2ncccn2)c2n1CCOC2)c1ccccc1 +c1ccc(CN2CCN(CC3COC(C4CCCCC4)(C4CCCCC4)O3)CC2)cc1 +O=C1Nc2ccc(Cl)cc2C(C#Cc2ccncc2)(C2CC2)N1 +Cc1ccc(C(=O)N2C3CCC2C(Nc2cnc(C(F)(F)F)cn2)C3)c(-n2nccn2)n1 +CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C)cc1O)CCCC3 +CN(C)C12CC(NC(=O)CN3CCCCC3)C(C(c3ccccc3)C1)C(c1ccccc1)C2 +CCOCCn1nc(CC)c2nc(N3CCNCC3)nc(Nc3cccc(C)n3)c21 +CON=C(CCN1CCN(c2ccccn2)CC1)c1ccccc1 +N#Cc1cccc2c1C=Cc1ncc(N3CCCCC3)cc1C2O +N#Cc1cncc(N2CCC(S(=O)(=O)c3ccccc3C(F)(F)F)C2)n1 +N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)cn3)o2)cc1 +CC(C)Oc1ccc(N=c2[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2CC2CCCC2)cc1Cl +CCCCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +CC(NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2c(N)cccc2F)cc1 +CCCCC#Cc1ccc(-c2c(C)c(C(=O)NC3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 +COc1ccccc1N1Cc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)c2C1=O +CCCCCCCCCCCCCCCC(=O)Nc1cccc(OP(=O)(O)O)c1 +COc1cccc(CNC(=O)c2cc3c(O)cccc3n2Cc2cccc(C(=N)N)c2)c1 +CCCC(C)N1CCC(C2NC(CNC(=O)c3ccc4cc(Cl)ccc4c3)CCN(CC(CC)c3ccccc3)C2=O)CC1 +O=C1NC(C(=O)O)Cc2ccc(cc2)OCC=CCOc2ccc(Cl)c1c2 +O=C1C(=O)N(CCc2ccccc2)c2c(Br)cc(Br)cc21 +O=C(C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2)Nc1ccccc1 +CCCCCCCCCCCCCC(=O)OCCCOP(=O)(O)OCC(N)C(=O)O +CC1(C)CNC(=O)c2sc(Nc3ccc(I)cc3Cl)c(C(=O)NCCC(O)CO)c2C1 +COc1ncc(Cl)cc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(Br)cc2)cc1)C(=O)O +COc1ccc2c(c1)C1(Nc3ccccc3-c3nc4ccccc4n31)C(=O)N2 +Cc1ccccc1-c1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2n1 +N#Cc1cccc(-c2nn(Cc3ccc(F)cc3F)c3c2CN(C(=O)c2ccncc2F)CC3)c1 +CC1=CC(=O)N(Cc2ccc(F)cc2)S(=O)(=O)O1 +COc1ncc(Cc2cn(CCCC(=O)N3CCN(c4ccc(Cl)cc4)CC3)c(SCc3ccc(F)cc3)nc2=O)cn1 +COCCN(CC(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)c1ccc2oc3ccccc3c2c1 +Cc1ccc2c(OCCN3CCC(Cc4cccc(N5CCN(C)CC5=O)c4)CC3)cccc2n1 +CC(=O)N1CCN(c2cc(-c3cccc(O)c3)nc(N3CCOCC3)n2)CC1 +O=C(CC1CCCC1)Nc1cnc(-c2ccncc2)c(-c2ccco2)n1 +COCC(COc1nc(Oc2ccc3c(c2)COB3O)c(Cl)cc1C#N)OC +COc1cc2ncnc(N3CCN(C(=NCc4ccc(C)cc4)NC#N)CC3)c2cc1OC +COCCOC(=O)C1=C(C)NC2=C(C(=O)CCC2)C1c1ccc(OC)c(OC)c1OC +CN1CCC(C(CCCCC(=O)N2CCC(CNC(=O)c3cc(Cl)cc(Cl)c3)C2)c2ccccc2)CC1 +O=C(O)c1[nH]c(=O)[nH]c(=O)c1CCc1cccc2ccccc12 +Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(Cl)c5)cc(C(F)(F)F)nc34)cn2)cn1 +CNC(=O)c1sc(C(C)(C)C)cc1NC(=O)Nc1ccc(C)cc1 +CCCN(CCC)c1cc(C)nc2c(-c3ncc(C)cc3Cl)c(C)nn12 +COCCC1CN(Cc2c(C)[nH]c(=O)c(I)c2Sc2cc(C)cc(C)c2)CCO1 +CCCCOP(=O)(CCCCC1(C(=O)NCCN2CCOCC2)c2ccccc2-c2ccccc21)OCCCC +CCNC(=O)c1ccc(-n2c(C)nc3cc(C)ccc32)s1 +CCNC(=O)OCc1c(COC(=O)NCC)c(-c2ccc(Cl)cc2)n2c1Cc1ccccc1C2 +CCOC(=O)C(O)=CC(=O)c1cn(Cc2cc(F)ccc2F)c2cccc(OC)c12 +c1ccc2cc3c(Nc4ccc(N5CCCCC5)cc4)ccnc3cc2c1 +Nc1ncc(-c2ccc(-n3cccn3)cc2)cc1C(=O)Nc1ccncc1 +CC12CCC(=O)C=C1CCC1C2CCC2(C)C(c3cccnc3)=CCC12 +COc1cccc(C2OC(CCn3ccc(CC(=O)O)n3)c3cccn3-c3ccc(Cl)cc32)c1OC +COc1nc(-c2ccncc2)nc2c1CN(C(=O)Nc1ccccc1)CC2 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)C1CCCCC1 +CC(C)=CCCC(C)SCCC(C)=CCCC=C(C)CCC=C(C)CCC1OC1(C)C +Clc1ccc(-n2cc(COCCCN3CCN(c4ccccc4)CC3)cn2)cc1 +O=C1CC2(CCN(C(=O)c3cc(-c4ccccc4)nc(-c4ccccc4)c3)CC2)Oc2cc(N3CCCC3)ccc21 +CC(=Cc1ccc(Cl)cc1)S(=O)(=O)Nc1cc(F)ccc1S(N)(=O)=O +CC(=O)NCCc1ccc(C(=O)CCCN2CCC(c3ccc(Cl)cc3)CC2)cc1 +CCC(CO)Nc1nc(Nc2cncnc2)c2ncn(C(C)C)c2n1 +COc1ccc(Cn2c(CC(C)(C)C(=O)O)nc3cc(OCc4ccc5ccccc5n4)ccc32)cc1 +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1cc(-c2ccc(F)cc2)c2ncccc2c1 +COc1ccccc1CNC(=S)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O +Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C(C)C +CC(C)(C)OC(=O)N1CC(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(c2ccccc2)C1 +COC(=O)CCCCCNC(=O)c1ccccc1N=Cc1ccccc1 +O=c1[nH]nc(Cc2ccc(F)c(CNC3CCOCC3)c2)c2c1CCCC2 +Oc1cc(Oc2cccnc2)cc(-c2cccc3[nH]ccc23)c1 +Cc1cccc(C2CC2COc2cc(NCc3ncc(C)s3)c(=O)n(C)n2)n1 +CCOC(=O)Cn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CCC1Cc2cc3c(C(F)(F)F)cc(O)nc3cc2NC1CC +CC(CO)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)c(C(F)(F)F)c3)c2)c2cncnc21 +CC1CN2c3c(cc4c(C(=O)N5CC(F)(F)C5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(C3CCN(C(=O)c4ccon4)CC3)nc21 +Clc1ccc2c(NCCNc3cc(Cl)nc(Cl)n3)ccnc2c1 +CCC1CN(c2nc(N)c(C(=O)NCC(F)(F)F)nc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +N=C(NCCCC(N)C(=O)NC1CCCNC1)N[N+](=O)[O-] +CCCn1c(C2CCN(C)CC2)nc(-c2ccc(Cl)c(Cl)c2)c1-c1ccnc(NC2CC2)n1 +CCCCN1CCN(C(=O)c2ccc(NCc3ccc(-c4cccc(F)c4C(=O)OC)cc3F)nc2)CC1 +CS(=O)(=O)N1CCc2c(-c3cnc(N)nc3)nc(N3CCOCC3)nc21 +COc1ccc2cc1Oc1ccc(cc1)CC1c3c(cc(OC)c(OC)c3Oc3cc4c(cc3OC)CCNC4C2)CCN1C +CCNC(=O)c1ccc(OCc2conc2C2CCC(F)CN2)nc1 +CCn1ncc2c(NCc3ccc(OC)c(Cl)c3)c(C(=O)NCCCCCO)cnc21 +Cc1cc(C)cc(Sc2c(CN3CCOCC3)c(C)[nH]c(=O)c2I)c1 +O=c1n(Cc2ccc(C(F)(F)F)nc2)nc2c(-c3ccncc3)c(-c3ccc(Cl)cc3)cnn12 +CN1CCC(c2ccc(Cl)cc2)C(COc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1 +CC(C)CN(NC(=O)OC(C)(C)C)c1nccc(C#N)n1 +O=C(Nc1ccc2cc(CN3CCCC3)cnc2c1)c1ccc(-c2ccc(Cl)cc2)cc1 +CNC(=O)Oc1cccc(CN(C)CCCCCCCOc2ccc3c(c2)OC(=Cc2c4ccccc4cc4ccccc24)C3=O)c1 +CN(C(=O)C1(c2ccc(F)cc2)CCC1)C1CCc2c(CC(=O)O)c3cccnc3n2C1 +Cc1c(C2CC2)sc(NC(=O)C2=C(C(=O)O)C3CCC2CC3)c1-c1nc(C2CC2)ns1 +COc1cc2c(N)nc(N3CCN(C(=O)CC(c4ccc(F)cc4)N4CCCCC4)CC3)nc2c(F)c1OC +COC1COCCC1NC1CC2CN(C(=O)OCC(C)(C)C)CC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +NC1CCC(C(=O)Nc2cc3cc[nH]c(=O)c3cc2Cl)C1 +COc1ccc(CNC(=O)c2cccc(NCc3nnc(-c4ccncc4)[nH]3)c2)cc1 +CS(=O)(=O)Oc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 +CC1CCCC(N2CCC(c3c(F)ccc(Cl)c3F)=CC2=O)c2cc(ccn2)-c2ccc(Nc3ncccn3)cc2NC1=O +CCC(CC)(NC(=O)c1ccc(N2CCC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC +Cc1nc(-c2ccc(F)cc2)ncc1C(=O)N(C)c1ccc(CN2CCNC(C)C2)cc1 +CCNC(=O)Nc1cc2c(-c3ccnc(C)c3)ccc(Cn3ccnn3)c2cn1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncc(Cl)cc1C(=O)O +O=C1CCC(=O)N1c1ccc(F)c(S(=O)(=O)Nc2cc(Sc3ncn[nH]3)c(O)c3ccccc23)c1F +COc1ccc2c(c1)CN(C(=O)CCN1CCCCC1c1nnc(Cc3ccccc3)o1)CCS2 +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCNC(=O)C5)ncn4)c3c2)cn1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1ccc(OCC(F)(F)F)cn1 +Cc1nc2ccccn2c1C(=O)NN=Cc1c(-c2ccccc2)no[n+]1[O-] +COc1ccnc(NCCCOc2ccc(CC(CC(=O)NO)NC(=O)c3ccc(OC(C)C)cc3)cc2)c1 +CCN(CC)C(=O)COCC(C)C1CCC(C)C(N(C)c2ncnc3[nH]ccc23)C1 +CNc1nc(NC2(C#N)CCCCC2)nc(-n2cnc(C)n2)n1 +O=C(C=Cc1ccc(Cl)c(Cl)c1)NCCCCCN1CCC(c2c[nH]c3cccc(O)c23)CC1 +NCCCc1cc2c(-c3ccc(Cl)cc3)c[nH]c(=O)c2c2cc(-c3cn[nH]c3)ccc12 +O=S(=O)(c1ccc(C2=CC3N=CN=C(Nc4ccc(OCc5ccccc5)c(Cl)c4)C3S2)cc1)N1CCOCC1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4cnccn4)s3)c2)C(O)C(O)C1O +COc1ccc(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)C(CCC(=O)NCC2CCCCC2)C(=O)NO)cc1 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCC1OCCO1 +N#Cc1ccc(Nc2nc(O)nc(Cc3c(Cl)cccc3Cl)n2)cc1 +COc1ccccc1N1CCN(c2ncnc3c2cnn3C2CCCC2)CC1 +Cc1ccc(C[n+]2cc(-c3ccc(F)cc3)n3c2CCC3)cc1 +CCCN(CCC)C(=O)Cn1c(=O)n2c3c(cc(-c4ccccc4)cc31)CCC2 +COCCOc1cncc(-c2cc3c(cn2)CCc2c-3[nH]c3c2C(=O)NCC3)c1 +Cc1ccc(C(=O)NN=C(Cn2c([N+](=O)[O-])cnc2C)c2ccc(Br)cc2)cc1 +CCCn1cc(-c2cc(C3C(=O)N(CC)c4ccc(C(F)(F)F)cc4N(c4ccccc4)C3=O)cc(OC)c2O)cn1 +CC1CCN(CCCOc2nc(-c3ccccc3)nc3c2CCCC3)CC1 +Cc1nnc2n1-c1sc(C#CCN3C(=O)COc4ccc(Cl)cc43)cc1C(c1ccccc1Cl)=NC2 +CC1=C(C(=O)Nc2cc3cn[nH]c3cc2F)C(c2ccc(C(F)(F)F)cc2)CC(=O)N1 +Cc1cccc(-c2ccc(OC(Cc3ccccc3)C(=O)O)cc2)c1 +O=C(O)CC(O)CC(O)C=Cc1c2c(nn1-c1ccc(F)cc1)C(Cc1ccc(Cl)cc1)CCC2 +Cc1ccc(-n2nc(C)c3c(=O)c4cc(Cl)ccc4n(O)c32)cc1 +Cc1cc(CNc2cc(OCC3CC3c3ccn(C)n3)nn(C)c2=O)nn1C +COc1ccc(S(=O)(=O)N(Cc2cn(C3OC(CO)C(O)C(O)C3F)nn2)C(C(=O)NO)C(C)C)cc1 +CC1CN(C(=O)N2Cc3c(NC(=O)c4ccn(C)n4)n[nH]c3C2(C)C)C(C)CN1CC1CCOCC1 +CCN(CCO)CCN(C(=O)Nc1ccc(F)c(Cl)c1)C1CCC2(c3cccc(C#N)c3)CC2C1 +Cc1cccc(NS(=O)(=O)c2ccc(C(F)(F)F)cc2)n1 +COc1ccc(-n2c(C)nnc2N2CCC(Oc3cc(F)cc(F)c3C)CC2)cn1 +CS(=O)(=O)Nc1ccc(OCC(O)CN(CCc2ccc(Cl)c(Cl)c2)CCc2ccccc2O)cc1 +COc1ccc(S(=O)(=O)C(CC(=O)NO)CN(C)C(=O)c2ccccc2)cc1OC1CCCC1 +CC(=O)NC1CCC(NC(=O)c2cnc(-n3ncc4cc(C#N)cnc43)cc2NC(C)C)CC1 +CCOc1ccc(OCC)c(NCC2CCc3nc(N)nc(N)c3C2)c1 +O=C(C1CC(N2CCN(Cc3ccccc3)CC2)CN1)N1CCSC1 +CCc1c(Sc2cc(C)cc(C)c2)n(CC2CCCC2)c(=O)[nH]c1=O +CC(=O)NNC(=S)NC(=O)C(c1ccccc1)c1ccccc1 +Cn1c(=O)c2nc(-c3cccc(O)c3)[nH]c2n(C)c1=O +CC(C(=O)NCCN(c1ccccc1)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCn1ccc(=Nc2ccc(Oc3ccccc3)cc2)c2ccc(Cl)cc21 +COc1ccc(-c2ccncc2)cc1C(C)(C)CC(O)(Cc1cc2ccncc2[nH]1)C(F)(F)F +COc1ccc(Cl)c(Nc2ncnc3cc(OC)cc(OC4CCN(C)CC4)c23)c1 +N#Cc1cccc(C(=O)Nc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)c1 +CCN(C(=O)c1cnn(-c2ccccc2)c1C)c1ccc(OC)nc1 +N#Cc1cccc(-c2cn(-c3ccc(C(=O)O)cc3)cc2C#N)c1 +c1ccc(OCCCN2CCc3c([nH]c4ccccc34)C2)cc1 +COc1cc(-c2c3c4cc(OC)c(O)cc4oc(=O)c3n3ccc4c(O)c(OC)c(OC)cc4c23)ccc1O +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nccn5c4)c3c2)CCC1=O +COc1cccc(-c2cc(C#N)ccc2COC(c2ccc(Cl)cc2)c2cncn2C)c1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C(C)C)nc1C +CS(=O)(=O)c1ccc(-c2c(-c3ccc(F)cc3)nn3ncccc23)cc1 +CC(NC(=O)N(C)NC(=O)c1cc(F)cc(C(F)(F)F)c1)c1ncc(C(=O)N2C(C)CCC2C)cc1F +O=S(=O)(Nc1nccs1)c1ccc2c(c1)OCCN2c1ccc2c(c1)OC(F)(F)O2 +CCN1CC(N(Cc2cc(Cl)ccc2Cl)c2ccc(C#N)c(Cl)c2)CC1=O +O=C(Nc1ccc(O)cc1)c1cccc(S(=O)(=O)N2CCCCC2)c1 +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CCCC2C(=O)NCCCCCC(=O)O)cc1 +CCNC(=O)c1ccc(Oc2cccc(CC(=O)O)c2)c(NS(=O)(=O)c2ccccc2)c1 +Cc1ccc(-c2nc(C)c(C(OC(C)(C)C)C(=O)O)c(-c3ccc4c(c3)CCCO4)c2C)cc1 +c1ccc(CCC2CNCCN2c2ccc3[nH]ncc3c2)cc1 +O=C(CCCCCCc1ccccc1)c1ncc(-c2nccs2)o1 +OC1CCN(c2cc(-c3cnc4ccc(N5CCCC5c5cccc(F)c5)nn34)ccn2)CC1 +CC(NC(=O)c1ccc2[nH]nc(-c3ccncc3)c2c1)c1cccc(Cl)c1 +CCOc1ncc(Oc2ccc(S(=O)(=O)Nc3ccc(F)cn3)cc2C#N)cc1Cl +CC(=O)N1C2CCC1CN(c1ccc(Nc3ncc4cc(C(=O)N(C)C)n(C5CCCC5)c4n3)nc1)C(=O)C2 +COc1cc2c(Oc3ccc(NC(=S)NN=Cc4ccco4)cc3F)ccnc2cc1OCCCN1CCCCC1 +O=C(N1CCOCC1)N1CCN(c2ccccc2C(F)(F)F)CC1 +CCOC(O)=C1C(COCCn2c(C)nc3ccccc32)=NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccc1Cl +Cc1cc(S(=O)(=O)N2C(CO)CCC2c2ccc(F)cc2)cc(Cl)c1F +Nc1cccc(CC2CNCC2OCCNCCc2cccc(F)c2)n1 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3C(F)F)nc12)N1CCC(O)C1 +COc1ccc(-n2nnnc2S(=O)(=O)CC(=O)N2CCCCC2)cc1 +CN1C2CCC1C(c1ncc(-c3ccc([N+](=O)[O-])cc3)s1)C(c1ccc(Cl)cc1)C2 +Cc1cc2c(OCC(O)CN3CCC(c4ccc5sccc5c4)CC3C)cccc2[nH]1 +CC(C)NC(=O)N(C(=O)C1CCC2C3CCC4NC(=O)CCC4(C)C3CCC12C)C(C)C +O=C(NNc1cccc2cnccc12)C12CC3CC(CC(C3)C1)C2 +CN(C(=O)CCC(=O)Nc1ccccc1)C(CN1CCC(O)C1)c1ccccc1 +Nc1nc2cc(-c3ccccc3)ccc2c(=O)n1CC1CCC(c2ccccc2)O1 +Cc1c(CCOCCCCCCOCCc2sc[n+](Cc3ccccc3)c2C)sc[n+]1Cc1ccccc1 +O=C(Nc1ccc(F)cn1)c1cc(Oc2cncnc2)cn2cnnc12 +C=CC(=O)Nc1c(C(=O)NCC)noc1-c1cc(Cl)c(O)cc1O 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+c1ccc(CN2CC(CN3CCC(c4ccccc4)CC3)C(c3cccc(-c4ccsc4)c3)C2)cc1 +O=c1n(-c2ccccc2)nc2c(NS(=O)(=O)c3ccccc3)nc3ccccc3n12 +CCC(C)(C)C(=O)C(=O)N1CCCC1C(=O)OCCCc1cccnc1 +CC1(C)C=Cc2c(ccc3c2OCC(c2ccc(O)cc2O)C3)O1 +CSCCCNC(=O)c1ccc2c(c1)NC(=O)C2=Cc1[nH]c(C)cc1C +CN(C)c1cc(NC(=O)Nc2ccccc2)c2ccccc2n1 +CCOC(=O)C1=C(N)N2C(=O)CCC(=O)N2C1c1ccccc1O +CC(Cl)(Cl)C(NC(=O)c1ccc(Cl)cc1)NC(=NC#N)Nc1cccnc1Cl +COc1ccccc1N1CCN(CCN(C(=O)c2ccc(CCl)cc2)c2ccccn2)CC1 +O=C(c1ccccc1Cl)N1CCC(CNCc2cccc(-n3cccn3)n2)CC1 +N#Cc1ccc(Cn2cncc2CNC2Cc3ccccc3CN(CC3CCCCC3)C2=O)cc1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2cc(Cl)ccc2o1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4cc5ccccc5o4)s3)c2)C(O)C(O)C1O +Cc1ccc(-c2cc(Br)ccc2OCc2cccc(F)c2F)n1-c1cccc(C(=O)O)c1 +CCOC1CN(C2CCN(C(=O)c3ccc4ncccc4c3)CC2)CCC1Cc1ccc(Cl)c(Cl)c1 +CCNC(=S)NNC(=O)Cc1nc2sc(C(=O)OCC)c(C)c2c(=O)[nH]1 +Cc1cccc(NCC(O)CON=C(C2CC2)C2CC2)c1 +COc1ccc(-c2snnc2-c2cc(OC)c(OC)c(OC)c2)cc1[N+](=O)[O-] +Cc1noc(C)c1CCNC(=O)Nc1nc2ccc(-c3cncc(S(=O)(=O)NC(C)(C)C)c3)cn2n1 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+O=[N+]([O-])c1ccc(N2CCN(c3nc(NCCc4c[nH]c5ccccc45)c4ccccc4n3)CC2)cc1 +CCCCn1cc2c(nc(NC(=O)Nc3ccccc3OC)n3nc(-c4ccco4)nc23)n1 +O=c1oc2cc3ncnc(Nc4ccc(F)c(Cl)c4)c3cc2n1CCCN1CCOCC1 +FC(F)(F)c1cc(CCCC2(c3ccccc3)CCNCC2)cc(C(F)(F)F)c1 +O=C1CCC(CCN2CC(N3CCC(O)CC3)C2)(c2ccc(Cl)c(Cl)c2)CN1CC1CC1 +O=C(c1ccc(O)cc1O)N(Cc1cccnc1)c1ccc(-c2nc(C(F)(F)F)ccc2C(F)(F)F)cc1 +O=C(C=Cc1ccc(-c2nnc(Cc3cccc4ccccc34)o2)cc1)NO +Cc1ncc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)c(=O)n(C)n1 +CC#CCOc1ccc(S(=O)(=O)C(C(=O)NO)C2CCCCC2)cc1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(c4ccccn4)CC3)c(C(F)F)c21 +N=C(N)NCCCC1C(=O)N(C(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)C1C(=O)O +CC(CN1CCCC1)Oc1ccc(C2Oc3ccc(O)cc3SC2c2ccc(O)cc2)cc1 +CC(O)(c1ccc(Cl)cc1)C(CN1CCCCC1)c1ccccc1 +Cc1nnc2n1-c1ccc(N3CCNCC3)cc1Cc1cc(-c3ccc(Cl)cc3)oc1-2 +CC(=Cc1cc(C)ccn1)C1CC2OC2(C)CCCC(C)C(O)C(C)C(=O)C(C)(C)C(O)CC(=O)O1 +CCN(CC)c1ccc(C=CC(=O)c2ccc(OC(=O)C3CC3)c3c2OC(C)(C)C=C3)cc1 +COc1cc2c3c(c4ccc(OC(=O)c5cccnc5)cc4c2cc1OC)CN1CCCCC1C3 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+N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCC#CCOc3c(F)cc(F)cc3C(=O)N2)CC1 +O=C1c2ccccc2C(=Cc2ccc(O)c(O)c2)c2sccc21 +CC(c1ccc(F)c(F)c1)n1cccc(C(=O)NCC#Cc2ccc3ncc(NC4CCN(C5COC5)CC4)nc3c2)c1=O +O=C1CN=C(n2cnc(C3CCC3)n2)C=C2c3cccc(-c4ccc(F)nc4)c3CCN12 +Cc1cnc(Nc2cccc(O)c2)nc1Nc1cccc(O)c1 +O=C(COc1ccccc1)N1CCCCC1c1noc(-c2ccc3[nH]c(=O)c(=O)[nH]c3c2)n1 +COc1cc(OCc2cccc(-c3ccc(Cl)cn3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CC(=O)Nc1nn(C)c2nc3nc4c(c(N)c3cc12)CCCC4 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CN2)c1C +COc1cccc2c1C(NCC1(c3ccccc3)CCC(NC(=O)OCC(F)(F)F)CC1)=NS2(=O)=O +CC(C)c1nc(C(=O)NC2CCN(CC(C)(C)F)CC2)c2ccccn12 +CC1=NNC(=O)C1=Cc1cn(-c2ccccc2)nc1-c1ccccc1 +CCN(C(C)=O)C1CCN(c2nc(-c3ccccn3)nc3c2CN(Cc2ccc(OC)cc2)CC3)C1 +CC(C)(COc1ccc(-c2ccc(-c3ncc(CC(F)F)[nH]3)cn2)cc1)C(=O)O +Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nn5)cc4=O)nc31)CNCC2 +N=C(N)NNS(=O)(=O)c1c(Br)c(Br)c(Br)c(Br)c1C(=O)O +O=C(O)c1cccc(Cc2c(-c3ccccc3)nn3cc(Cl)ccc23)c1 +CCc1sc2c(NC(=O)C3(O)CC3)c(OC)nn2c1-c1c(OC)cc(COC)cc1OC 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+CCN(C(=O)Cc1ccc(OC(F)(F)F)cc1)C1CCN(CCC(c2ccccc2)c2ccccc2)CC1 +COc1cc2c(=O)n(CCNC(C)C)c3c4cc5c(cc4ncc3c2cc1OC)OCO5 +COc1ccc(C(=O)NCC2(C(F)(F)F)OC(=O)Nc3ccc(Cl)cc32)cc1 +OCc1cccc(-c2nc(N3CCOCC3)c3ncn(C4CCN(c5ccc(F)cc5F)CC4)c3n2)c1 +Cc1ccc(NC(=O)C2CSc3c(C4CC4)c(Cc4cccc5ccccc45)c(N)c(=O)n32)cc1 +O=C(Nc1ccccc1)c1ccc(CC2CCN(C3CCN(C(=O)c4ccc(F)c5ccccc45)CC3)CC2)cc1 +CC(NC(=O)c1ccc2[nH]nc(-c3ccncc3)c2c1)c1ccccc1Cl +COc1cccc(-c2cccc(C3(C)CCSC(N)=N3)c2)c1 +O=c1[nH]c2c(O)ccc(C(O)CNC3CCCCCC3)c2s1 +COc1ccc2c(CC(=O)Nc3cc(Br)ccc3N3CCN(C(=O)OC(C)(C)C)CC3)cc(=O)oc2c1 +CC(NC1=NC(=O)C(C)(C(C)C)S1)c1ccccc1Br +O=c1nc(-c2ccc3[nH]ncc3c2)cc(-c2cccc(Cl)c2)[nH]1 +CN(C(=O)c1ccc(CN2C(=O)Nc3ccc(Cl)cc3S2(=O)=O)cc1)C1CCCCCC1 +COc1ccc(S(=O)(=O)N(Cc2cn(CCOCCOCCOCCN=[N+]=[N-])nn2)C(C(=O)NO)C(C)C)cc1 +O=C1NC2CSC(CCCCCc3cn(Cc4ccc(F)cc4)nn3)C2N1 +CCCCCC12CCC(COc3cc(F)c(C(=O)NS(C)(=O)=O)cc3Cl)(CC1)CC2 +COc1ccc(Nc2ncc3c(n2)-c2ccc(C)cc2NC(=O)C3)cc1OC +CC(C)(C(=O)N1CCC(CC(=O)O)CC1)C(NC(=O)c1ccc(C(=N)N)cc1)c1ccc2ccccc2c1 +Cc1[nH]nc2c1C(c1cc(N3CCS(=O)(=O)CC3)cc(C(F)(F)F)c1)(C(C)C)C(C#N)=C(N)O2 +[H]c1cc([H])c([H])c(-c2nc3c([nH]2)C2=NC(CC)CN2C(=O)N3C)c1 +Cc1cc(Oc2cc(NC(=O)C3CC3)ncn2)ccc1NC(=O)Nc1cc(NC(C)C)cc(C(F)(F)F)c1 +CN1C(=N)NC(C)(c2cc(-c3cccc(C#N)c3)cs2)CC1=O +Cc1cc(NC(=O)Nc2ccccc2)n(-c2ccccc2)n1 +Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3N3CCOCC3)cc2)no1 +CCOCCN1CCN(c2cncc(-c3cn(-c4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4C)nn3)c2)CC1 +C#CCSc1nc(Sc2ccccn2)c2nnn(Cc3ccccc3)c2n1 +CC(C)c1cc(Nc2cc(OCCN3CCOCC3)nc(NCc3cc(-c4ccccc4)no3)n2)n[nH]1 +CC1OC(OC2C(CO)OC(O)C(O)C2O)C(O)C(O)C1NC1C=C(CO)C(O)C(O)C1O +Nc1nc(Cl)c(C#Cc2ccccc2)c(NC2CC(CO)C(O)C2O)n1 +Cc1ccccc1Cc1cc(CCC(=O)O)c2c(c1)CC(NS(=O)(=O)c1ccc(Cl)cc1)CC2 +CCC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2Cc2ccc(F)cc2F)C1 +Fc1ccc(C(OC2CC3CCC(C2)N3CCOCCN2CCOCC2)c2ccc(F)cc2)cc1 +Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(Cl)cc3)n2)c1 +COc1ccc(-c2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1OCCN(C)C +CC1CCC2C(C)C(CC(=O)NCCCCNCCCN)OC3OC4(C)CCC1C32OO4 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(F)c(F)c3)nn21 +CNC(C)C(=O)Nc1cc(-c2nccc3cccc(C)c23)cc(NC(=O)c2ccc(Cl)cn2)n1 +CN(C)C(=O)C1CCC(C(=O)N2CCC3(C)c4ccccc4CC2C3(C)C)CC1 +CCc1cc(C#N)cc2c(NCc3ccc(OC)c(Cl)c3)ccnc12 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)C=CC(C)=O)cc1 +CCC(NC(=O)N1CC(=O)Nc2cccnc21)c1ccc(OC(F)(F)F)c(F)c1 +Cc1ccccc1-c1ccc(C=CC2C3CCC(O)CC3CC3C(=O)OC(C)C32)nc1 +CNCc1cc(C#CCCN2CCCCC2)ccc1Oc1ccc(SC)cc1 +CC(=O)c1ccc(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1 +CCS(=O)(=O)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1 +CN1CCC=C(C2CN(C(=S)Nc3ccc(Cl)cc3)CCO2)C1 +N#Cc1ccc(-c2ccc(C(=O)C(F)(F)F)s2)cc1 +COc1ccc(OC(C)(C)C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)cc1 +O=C(Nc1cccc(Nc2nccc(-c3cccnc3)n2)c1)C1CCCCC1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)N1CCCC1B(O)O +CC(=O)CCCC(=O)NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCCc2ccccc2Cl)C1=O +O=S(=O)(Nc1ccc(Nc2c3ccccc3nc3ccccc23)cc1)c1ccccc1 +COc1cc(OC)cc(C(=O)NC(NC(=NC#N)Nc2ccccc2C)C(C)(C)C)c1 +Cc1ccc2[nH]cc3c(=O)n(-c4csc(C)c4)nc-3c2c1 +CC1(C)C=C(c2nc3cc(C(N)=O)ccc3[nH]2)CC(C)(C)N1 +Cc1cn(CC(CO)OCP(=O)(O)O)c(=O)[nH]c1=O +Cn1nc(NCC(=O)NC2CN(C3CCC(C#N)CC3)C2)c2cc(C(F)(F)F)ccc21 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)C2)CCN1Cc1ccc(F)c(Cl)c1 +COc1cc(C#N)cc(-c2cc3nc(C)ccc3cn2)c1 +COC(=O)c1c(NC(=O)c2ccc([N+](=O)[O-])o2)sc2c1CCN(C(C)C)C2 +O=C(NCCCn1ccnc1)c1cnc(N(Cc2ccc(F)cc2)C(=O)CN2CC=CCC2)s1 +COCCOCCOCCOCCOC1CCC2(O)C3Cc4ccc(OC)c5c4C2(CCN3C)C1O5 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1Cc1cccs1 +N=C(N)Nc1ccc(Oc2cccc(Oc3ccc(NC(=N)N)cc3)c2)cc1 +COc1ncc(-c2cnc3[nH]cc(C(=O)c4c(F)ccc(NS(=O)(=O)c5c(F)cccc5F)c4F)c3c2)cn1 +CC#CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CC(=O)c1ccccc1)c(=O)n2C +CCCC1CCCCN1C(=O)C(NC(C)=O)C1CC(C(=O)O)CC1N=C(N)N +COc1cc2nc(-c3ccc(OC)c(N4CCN(C)CC4)c3)cc(O)c2cc1-c1cnco1 +Cc1c(C(Cc2ccc(F)c(F)c2)P(=O)(OC(C)C)OC(C)C)sc2ccccc12 +O=C(Nc1cnc2[nH]ccc2c1)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +NC(=O)Cn1c(=O)c(=O)n(C2CCN(C3Cc4cccc5cccc3c45)CC2)c2ccccc21 +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(C)nn2C)C3=O)c(OC)n1 +Cc1c(Cc2ccc(=O)n(Cc3ccc(C(F)(F)F)cc3)n2)c2cc(F)ccc2n1CC(=O)O +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(N2CCOCC2)nc1OCCNS(=O)(=O)c1cccs1 +CCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1ccc(Cl)cc1Cl +COC(=O)C1Cc2ccc(OCCc3nc(-c4ccc(OC)cc4)oc3C)cc2OC1=O +C=C(c1c(C)ccc(C)c1OCC(O)CNC(C)(C)C)n1ccnc1 +CCCNC(=O)Nc1cc(C=CC(=O)NO)ccc1SCCN(CC)CC +COc1ccc2nc(SCc3ccc(C(=O)Nc4ccccc4N)cc3)[nH]c2c1 +Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)cc1C(F)(F)F +Cn1c(-c2ccccc2Cl)csc1=NC(=O)c1ccccc1 +Cc1nc2cc(-c3cc(OC(C)C4CNC(=O)C4)c4cccnc4c3)ccc2n1C +COCCN1Cc2cccc(C(=O)Nc3ccc(-c4nc5ccccc5[nH]4)cc3)c2C1=O +CCc1ccc(NCc2cnc3nc(N)nc(N)c3n2)cc1C(=O)N1CCC(C(=O)OC)CC1 +CNC(=O)OCc1ccc(Cl)c(CN(C(=O)C2CNCCC2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(Cl)c3)cc12 +CCNC(=O)Nc1nc2ccc(-c3ccc(OC)cc3OC)cc2s1 +CCCc1cc(C(=O)NC(Cc2ccc(-c3cccc(C(F)(F)F)c3)nc2)C(=O)NCCN(C)C)sc1C +Nc1ncc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCCCCC3)cn2)cn1 +Cn1cncc1CN(CCN(CC1CCCCC1)S(=O)(=O)c1ccccn1)c1ccc(C#N)cc1F +CC(NC(=O)Nc1cc2[nH]nc(-c3cnc(O)nc3)c2cn1)c1ccccc1 +CCOC1Oc2c(Br)cc(Br)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O +N#Cc1ccccc1C(O)(c1ccc(Cl)cc1)c1cccnc1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cnn(C)c2)CC1 +CC(C)(C)c1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CC(=O)c1ncc(CNC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)s1 +CC(C)c1n[nH]c2c(=O)[nH]c(CC3CCCCC3Nc3ncccn3)nc12 +CC1(c2ccccc2)CCN(Cc2ccc(Br)cc2)C(=O)O1 +CCn1cc(-c2nc3c(N4CCN(Cc5cc(C)on5)CC4)c(Cl)cnc3[nH]2)cn1 +COc1ccc(C=NNc2cc(N3CCCC3)nc(N3CCCC3)n2)cc1 +CN(C)CCn1cc(S(=O)(=O)c2cccc(Cl)c2)c2cccnc21 +CC(C)COc1ncc(N2C(=O)C3(CC3)c3cc4c(NS(C)(=O)=O)noc4cc32)cc1Cl +O=C(NC(CCC(=O)N1C(C(=O)O)CC2CCCCC21)C(=O)O)OCc1ccccc1 +CC1NC(CO)(CNC(=O)C(N)CO)C(O)C(O)C1O +CC1(C)Oc2ccc(S(=O)(=O)c3ccccc3)cc2C(N=C(NC#N)Nc2ccc(Cl)cc2)C1O +O=C(c1cccc2c1C(=O)N(Cc1ccccc1)C2)N1CCCC1 +CC1=C2C3OC(=O)C4(CC(c5ccc(Br)c(F)c5)=NO4)C3CCC2(C)C=CC1=O +Cc1ccc(CN2CC(C)OC(C)C2)cc1NC(=O)c1ccc(Nc2ncc(C)c(-c3cnn(C)c3)n2)cc1 +CC(=O)Nc1cc(-c2ccc(C)cc2)cc(-c2ccc(C)cc2)n1 +CCN(CC)C(=O)c1ccc(NC(=O)NC(Cc2ccc(O)cc2)C(=O)NC2CCN(Cc3ccc(C#N)cc3)C2)cc1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccn(Cc2cccc(Cl)c2)c(=O)c1 +CCN(Cc1cccc2ccccc12)c1cc(N2CCOCC2)nc(=O)[nH]1 +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cn[nH]c3)nc12 +O=C(CC1CNCCN1c1cc(Cl)nc(-n2ccnc2)n1)NCc1ccc2c(c1)OCO2 +CC(O)C(O)C(=O)N(CCCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1ccccc1 +COc1cc(Nc2ncnc(-c3cccnc3Nc3cccc(C(=O)Nc4ccc(Oc5ccccc5)cc4)c3)n2)cc(OC)c1OC +COc1cncc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +COc1ccc(Cn2ccc3nc(N)nc(NCc4cc(C)on4)c32)nc1OC +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(Cl)cc3)nc(CO)c12 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCC(NCc2ccc(Cl)cc2)CC1 +N#CC1CN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)C1 +CC(C)c1n[nH]c2c(=O)[nH]c(CC3CCCCC3OCCN3CCOCC3)nc12 +Nc1nnc(-c2ccc3[nH]cc(-c4csc(-n5ccccc5=O)n4)c3c2)s1 +COc1ccc(N(Cc2ccc3ccccc3n2)C(=O)c2ccc(C=CC(=O)NO)cc2)cc1 +c1ccc(CCn2nnnc2C(c2cccnc2)N2CCN(c3nc4ccccc4s3)CC2)cc1 +Nc1nccc(-c2c[nH]c3cc(C(F)(F)F)ccc23)n1 +COc1cc2cc(CO)c(CO)c(-c3cccc(-n4nc(-c5cccnc5)c5ccccc5c4=O)n3)c2cc1OC +C1=CCc2c(-c3ccccc3)[nH]c(-c3ccccc3)c2C1 +CC1CCN(C(=O)c2ccc3c(c2)c2c(n3S(=O)(=O)N(C)C)CCN(C3CCCC3)C2)CC1 +O=C(Cc1c(-c2ccccc2)nc2c(Cl)cc(Cl)cn12)N1CCc2ccccc2C1 +CCCc1nc2[nH]c(-c3ccccc3)nc(-c3ccccc3)c-2n1 +c1ccc2c3c([nH]c2c1)C(C1CCOCC1)NC(c1nc(C24CC5CC(CC(C5)C2)C4)c[nH]1)C3 +CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OCCCCc1ccccc1 +Cc1cc(C2C3CCC(CC2c2ccc(F)cc2)S3)on1 +CCc1cc(Oc2c(C)cc(NC(=O)C(=O)O)cc2C)ccc1O +O=C(O)C1=CCCN(CCOC(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)C1 +CC(C)COc1ccc(CN(Cc2ccc(F)cc2)C(=O)NC2CCN(C)CC2)cc1 +c1cc(C[n+]2ccc(C3CCCCC3)cc2)cc(-c2cccc(C[n+]3ccc(C4CCCCC4)cc3)c2)c1 +COc1cnc(NCc2ccccc2)nc1-c1cc2c([nH]1)CCNC2=O +NC(=O)c1cc(S(N)(=O)=O)c2c(c1)nc(NCc1ccccc1Cl)n2CC1CCCCCC1O +CCN(CC)CCOc1cccc(-c2cc(C(=O)NC3CCCNC3)c(NC(N)=O)s2)c1 +Cc1ccccc1C(CC(=O)O)NC(=O)c1cc(Sc2ncccn2)ccn1 +CCNc1c(C(N)=O)nnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc12 +O=C(c1ccc(C(=O)N2CCCc3ccccc32)cc1)c1cnc2ccccn12 +COc1nc(-c2cn3c(n2)C(c2cc(Br)ccc2C(F)(F)F)CCC3)ccc1-n1cnc(C)c1 +CCc1cn(-c2ccc(C(N)=O)c(NCCN3CCOCC3)c2)c2nccc(-c3cnc4ccccc4c3)c12 +Cc1c(C(=O)NCCO)sc2ncnc(Nc3ccc(F)cc3OC(CO)CO)c12 +Cc1cc(C)c(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1NC(=O)c1ccc(N2CCOCC2)nc1 +CCNc1cc(Cl)cc2c1[nH]c1cnc(NCc3ccccc3)cc12 +Nc1ncnc2nc(-c3cccs3)c(Cc3cccc(Br)c3)cc12 +Oc1nc2cc(-n3ccnc3)c(C(F)(F)F)cc2nc1O +CNc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2F)ncn1 +CCN(Cc1ccc(OC)cc1)Cc1ccc(-c2cc(S(=O)(=O)CC)ccc2OC)[nH]1 +O=C(c1nnco1)C1CCc2cc(Oc3ccccc3)ccc2C1 +COc1cc(CN(CC2CCCC2)C(C(=O)O)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CCC1=O +CC(=O)c1cccc(CC(NC(=O)c2c(Cl)cc3c(c2Cl)CCN(C(=O)c2ccc4ccoc4c2)C3)C(=O)O)c1 +CC(NC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1)c1cnn(C)c1 +CN1CCC(NC(=O)c2csc(NC(=O)c3ccc4cc5n(c4c3)C3(CCC3)CNC5=O)n2)CC1 +NC1=NC(c2cccc(NC(=O)c3ncc(Br)cc3O)c2)(C(F)F)COC1 +CC1CN(C(C)(C)CO)CCN1C(=O)CC1(C2COCC(C3CC3)N2S(=O)(=O)c2ccc(F)cc2)CC1 +N#Cc1cccc(N=Nc2c(Cl)nc(N)nc2NC2CC(CO)C(O)C2O)c1 +C=CCN1CCC23c4c5ccc(O)c4OCOC46CCC2(OC(C(=O)N4Cc2ccccc2)C63)C1C5 +COc1ccc(S(=O)(=O)N(Cc2cccnc2)C(CCF)C(=O)NO)cc1 +CC(C)S(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CCC(N4CCC(F)(F)CC4)CC3)cc2C(N)=O)cc1 +Cc1cccc(CCOC(=O)C2=C(c3ccccc3)CCN(C)C2)c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(OCc4ccc(Cl)cc4)nc23)N1 +CC(C)CC(C(=O)NCC#N)c1cccc(-c2cccc(-c3csc(N4CCN(C)CC4)n3)c2)c1 +CC(=O)NC(C(=O)N1CCCCC1)C1CC(C(=O)O)CC1N=C(N)N +Cc1c(N)cc(-n2c(C)ccc2-c2cc(C(F)(F)F)ccc2OCc2ccccc2)cc1C(=O)O +CC(=O)OC(C)C(=O)Nc1cccc(-c2n[nH]c3ccc(-c4nn[nH]n4)cc23)c1 +C[N+](C)(C)CCOc1cnc2c3c(cccc13)C(=O)c1ccccc1-2 +NC(=O)C[S+]([O-])C(c1ccccc1)c1cccc(Br)c1 +CCCCCCCCNC(=O)C1CCC2C3CCC4N(C)C(=O)C=CC4(C)C3CCC12C +CC(C)(C)n1nnnc1C(c1cccc(Nc2ccnc3cc(Cl)ccc23)c1)N1CCCC1 +COc1cc(O)c2c(c1C(=O)NCc1cc(OC(C)=O)cc3ccccc13)OC1=CC(O)=C(C(C)=O)C(=O)C12C +O=C(Nc1ccc(Cl)cc1)NC1N=C(c2ccccc2)c2ccccc2N(CC(O)CO)C1=O +O=C(CN1CCN(Cc2ccccc2)CC1)c1c[nH]c2ccc(O)cc12 +OCCn1cc(-c2cc(OCCC34CC5CC(CC(O)(C5)C3)C4)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +Cc1ccc(N(CC2=NCCN2)c2cccc(O)c2)cc1 +N#Cc1cc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cnc1N1CCC(O)C1 +Cc1nnc2n1-c1sc(C#CCn3ncc4ccccc43)cc1C(c1ccccc1Cl)=NC2 +CC(C)n1cnc2c(NCc3ccc(-c4ccoc4)s3)nc(NC3CCC(N)CC3)nc21 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCCN(C(=O)C(C)C)C2)cc1 +NC(CC(=O)N1CCn2nnc(-c3ccoc3)c2C1)Cc1cc(F)c(F)cc1F +CCCCCc1nc(N)c2nc(-n3nccn3)n(C)c2n1 +O=C(C=Cc1ccc(O)c(O)c1)c1ccc(S(=O)(=O)N2CCCCCC2)cc1 +Nc1ccn(C2OC(COP(=O)(O)OC(C(=O)N3CCCCC3)P(=O)(O)O)C(O)C2O)c(=O)n1 +O=C(Cc1ccccc1)Nc1nc2nn(CCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +NC(C(=O)N1CCN(c2ccc3[nH]ncc3c2)CC1)c1cccc(Cl)c1 +Nc1nccn2c(C3CCC3)nc(-c3cccc(OCc4c(F)cccc4F)c3)c12 +O=C(O)CC(c1ccc(OCc2cccc(-c3ccc(C(F)(F)F)cc3)c2)cc1)c1cccnc1 +Cc1ccccc1N1CCN(Cc2ccc(C(O)c3ccccc3)cc2)CC1 +O=C(Nc1cc(-c2cccc(NS(=O)(=O)c3ccccc3)c2)n[nH]1)c1ccc(N2CCOCC2)cc1 +CC(C)(C)OC(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 +COc1ccc(-c2cc3c(NC(=O)CC4CCCC4)ncnc3o2)cc1 +CN(CCO)c1nc(NC2CCCC2C#N)c2cc[nH]c(=O)c2n1 +N#Cc1ccc(N(Cc2ccc(OS(N)(=O)=O)c(F)c2)n2cnnc2)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)C2CC3C=CC2C3)CC1 +CC(C)(C)COc1cc(C(C)(C)C)ccc1CN=C(S)NCc1ccc(NS(C)(=O)=O)cc1 +Cn1cc(C(=O)N2CCC(c3cccc(CN)c3)CC2)c2ccccc21 +CC(C)Oc1nc(NC2CCOC2)ncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 +COc1ccc(Cl)cc1S(=O)(=O)N1COc2c(F)cc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 +CCc1nc(N)nc(N)c1-c1ccc(NCc2ccnc(Cl)c2)cc1 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCCC2)CC1 +Cn1ccc2cc(C(=O)N3CCc4c(cnn4-c4ccccc4Cl)C3)ccc21 +Cc1cc(C)cc(C(CC(C)C)NC(=O)c2cc(COc3cccc(Cl)c3)ccc2CCC(=O)O)c1 +C=C1C(=O)C23C(=O)OC4CCC(C)(C)C5C(O)OCC45C2CCC1C3OC(=O)c1ccc(OC)cc1 +Oc1ccc(-c2cnc3c(-c4ccnc5ccccc45)cnn3c2)cc1 +CC(C)=CCn1cc(C[N+](C)(C)C)c2ccccc21 +CC(C)c1cn2ccccc2c1S(=O)(=O)c1ccc(OCCCNCCc2ccccc2)cc1 +COCCN1C(=O)Cc2ccc(-c3ccc(CC(C#N)NC(=O)C45CCC(CC4)CN5)c(F)c3)cc21 +COc1cc2c(cc1N1CC(C)N(C)C(C)C1)N(C(=O)Nc1cccc(C(F)(F)F)c1F)CC2 +Cn1c2c(c3cc(C(=O)N4CCCCC4)ccc31)CN(C1CCOCC1)CC2 +Cc1cc(Oc2ccnc(NC(=O)C3CC3)c2)ccc1NC(=O)Nc1cc(C(C)(F)F)ccc1F +O=S(=O)(Nc1cccc(CCc2ccccn2)c1)c1cc(Cl)ccc1Cl +CC(O)CNc1nccc(-c2nc(C3CC3)[nH]c2-c2cccc(NS(C)(=O)=O)c2F)n1 +CC1(COc2cc(F)c(C(=O)NS(=O)(=O)N3CCC3)cc2C2CC2)CCC(C(F)(F)F)CC1 +COc1ccc(-c2nc(-c3ccncc3)cnc2N)cc1OC +COCC(=O)NCCNc1nc(-c2ccc(C(C)(C)O)nc2)cc2ncn(C)c(=O)c12 +Cc1ccc(C(=O)N2CCOCC2Cc2cc(Cl)cc(-n3nccn3)c2)c(-n2nccn2)c1 +CCOC(=O)c1nc(-c2ccc(F)cc2)c(-c2ccc(S(C)(=O)=O)cc2)s1 +CCCCc1ncc(CO)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(CNC(=O)CCCCCN2CCN(c3ncccc3-c3ccncc3)CC2)cc1 +Nc1nc(C(=O)N2Cc3ccccc3C2)c2cc(O)ccc2n1 +CNC1CCN(C2CCC(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 +O=S(=O)(NCCCN1CCOCC1)c1ccc2c(c1)Cc1c-2nc(O)c2ccccc12 +COc1ccc(C(C)C)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 +CCCN(CCN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)c(F)c1)S(=O)(=O)CC(C)C +CCC(Cc1ccccc1)c1cc(O)c(C(c2cccc(NS(=O)(=O)c3cccc4cccnc34)c2)C2CC2)c(=O)o1 +CCc1nc(-c2ccccc2)c(C)c(-c2ccc(F)cc2)c1CCP(=O)(O)CC(O)CC(=O)O +CNc1ncnc2c1ncn2C1OC(CN(CCCNC(=O)Nc2ccc(C(C)(C)C)cc2)C(C)C)C(O)C1O +Nc1ccc(Nc2nc3c(Br)c(Br)c(Br)c(Br)c3[nH]2)cc1 +Cc1cc2nc(-c3cccc(O)c3)nc(N3CCOCC3)c2s1 +CCOc1cc(=O)n(C)cc1-c1cc(N(Cc2cccnc2)S(=O)(=O)Cc2ccccc2)ccc1Oc1ccc(F)cc1F +c1ccc2c(-c3cnn4cc(-c5ccc(N6CCOCC6)cc5)cnc34)ccnc2c1 +NC(=O)c1ccc(Oc2ccc(CCNCc3cccc(F)c3)cc2Cl)nc1 +CC(=NNC(=O)c1cc2ccccc2cc1O)c1ccccn1 +CCc1cnc(N2CCC(n3nnc4cc(-c5ccc(S(C)(=O)=O)cc5)ncc43)CC2)nc1 +O=C(Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)Nc1ccccc1 +O=C(O)c1ccccc1Nc1cccc([N+](=O)[O-])c1 +COc1c(OCC2CC2)ncnc1N1CCC(Oc2ccc(C(C)NC(=O)C3(C)CC3)cc2)C1 +CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCO)cc1C(C)(C)C +Cc1ccc(-c2ncccn2)c(C(=O)N2CCCOC2Cc2cnn(-c3ccc(F)cn3)c2)c1 +COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2c(F)cc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 +CCCCCCNC(=O)CCC(NS(=O)(=O)c1ccc(-c2ccccc2)cc1)C(=O)O +O=C(Nc1cnc2[nH]nc(C3CC3)c2c1)c1c(F)ccc(NS(=O)(=O)CCCF)c1Cl +C=CCCn1c2c(n3ccnc3c1=O)Cc1c(-c3cccnc3)cccc1-2 +[N-]=[N+]=NCCSSCCn1cc(C(=O)CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)nn1 +CC(C)CCn1c(Cn2c(=O)n(CCCCC#N)c3ccccc32)nc2ccccc21 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+N#Cc1cc(-c2ccnc(Nc3ccc4c(c3)CC(=O)N4)n2)ccc1N1CCCC1 +O=C(C1CCCN(c2ccc3nc(-c4cncc(C(F)(F)F)n4)[nH]c3n2)C1)N1CCCC1 +Cc1ccc(C(Nc2nsnc2Nc2cccc(C(=O)N(C)C)c2O)C(C)(C)C)o1 +CC(C(=O)Nc1ccc(C(=O)O)cc1)n1ccc(-c2cc(Cl)ccc2C#N)cc1=O +COc1ccc(C2CC2COc2cc(NCc3cc(C)on3)c(=O)n(C)n2)nc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc4[nH]ccc4c3)NC(=O)NC1=O)C2 +COC1(c2cc(Sc3ccc4c(c3)OCC(=O)N4C)cc(F)c2C)CCOCC1 +CCOc1ccc(S(=O)(=O)N2CCOCC2)cc1-c1nnc2c(n1)c(C)nn2C +C#CCn1c(=O)c2c(nc3n2CCCN3C2CCC2)n(C)c1=O +CCCCCCCCNC(=O)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)Cc1ccccc1 +CC1CC(=O)NN=C1c1ccc(N)c([N+](=O)[O-])c1 +C#CCN(C)CC(=C)c1cccc(OCc2ccc(OC)cc2)c1 +OCC1OC(c2cc(Cc3ncc(-c4ccco4)s3)c(Cl)cc2F)C(O)C(O)C1O +CC(C)c1cccc(NC(=O)C2CC(N)CN2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 +Fc1ccccc1CC1=NC(c2ccccc2)C(c2ccccc2)N1 +NS(=O)(=O)NCCCCC(NC(=O)OCc1ccc(Cl)cc1)C(=O)Nc1nc(-c2ccccc2)cs1 +NCC(O)CNc1cc(N2CCC(c3ccccc3)CC2)nc2ccccc12 +COc1cc(NC(=N)NC(=O)c2ccccc2)ccc1-c1cnco1 +CN1CCN(c2ccc3[nH]nc(S(=O)(=O)c4cccc(F)c4)c3c2)CC1 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+CCCCC1(CCCC)C(O)C(c2cccc(NC(=O)CCCCBr)c2)c2cc(N(C)C)ccc2S(=O)(=O)N1C +Cc1ccccc1CC(O)C=CC1C(O)CC(=O)C1SCCCSCC(=O)O +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2cc(Cl)ccc12 +CC(Oc1cc(-c2ccc3[nH]cnc3c2)cc2ncccc12)C1CNC(=O)C1 +CCc1c(Sc2ccc(Br)cc2)[nH]c2nc(N)nc(N)c12 +CC(C)OC(=O)Nc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1)Nc1ccc(C(F)(F)F)cc1Cl +Cc1ccc(C#N)c(OCc2ccc(C(=O)Nc3ccccc3N)cc2)n1 +Cc1nc(NC(C)c2cccc(OCCn3ccnc3C)c2)cc(-c2ccc3ncsc3c2)n1 +COc1ccc(C(=O)CC(=O)CC2CCN(Cc3ccccc3)CC2)cc1OC +COC1(c2ccc(Cl)cc2)CCN(Cc2c[nH]c3ccccc23)CC1 +O=C(Nc1ccc(Cl)nc1)c1ccc(C(F)(F)F)c(F)c1 +Nc1ccccc1NC(=O)c1ccc(NC(=S)NCc2nc3ccccc3[nH]2)cc1 +CC1(C)CC(Nc2ccccc2S(=O)(=O)Nc2ccc3c(c2C(=O)O)CCCC3)CC(C)(C)N1 +Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4nc(C)c(C)n4-5)CC3)cccc2n1 +Cn1c(C#Cc2cc3ccc(Br)cc3[nH]2)cc2ccc(Br)cc21 +[C-]#[N+]c1cccc(-c2ccc3c(c2)CN2CCC3(c3ccc(Cl)cc3)CC2)c1 +C=CCN1C(=O)n2c(cc3c(OC)cc(OC)cc32)C1=S +NC(=S)Nc1cccc(OCCCCCOc2ccc(-c3ccccc3)cc2)c1 +O=C(CCc1c[nH]c2ccccc12)NCCCN1CCC2(CCc3ccccc32)CC1 +Cc1cc2cc(OCC(=O)O)cc(Cl)c2n1Cc1ccc(O)c(C(C)C)c1 +COc1ccccc1N1CCN(CCC2CCc3ccc(N)cc3C2=O)CC1 +COc1ccc(Cl)c(NC(=O)Nc2cc(Nc3ccc(N4CCN(C)CC4)cc3)ncn2)c1Cl +CNC(=O)c1c(NCC2CCC3(CCC3)CC2)nc(C#N)nc1OC1CC(C)(C)NC(C)(C)C1 +COc1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)cc1CCCN(C)C +CCN(CC)Cc1ccc(-c2cccc(CN(C)C(=O)CN)c2)cc1 +CC(C)c1nc2cc(Cl)c(Cl)cc2nc1S(C)(=O)=O +CNC(=O)C1Cc2cc(-c3ccncc3)ccc2N1C(=O)COc1ccc(F)cc1 +O=C(Nc1ccc(F)cc1)Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +Cn1c(=O)ccc2c(NC(=O)NC3CC(CF)(CF)Oc4cc(Cl)ccc43)cccc21 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)CNCc2cccc(OC)c2)c1 +COc1cc2c(cc1-c1ccc(I)cc1)NC(=O)CC(c1cccc(-n3ccnc3)c1)=N2 +NC(=O)c1c(NC(=O)c2ccc(OCc3ccccc3)cc2)sc2c1CCN(Cc1ccccc1)C2 +Cc1cc(C(=O)NC(C)(C)C)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 +O=C(COCc1ccncc1)N1CCC(c2ccc(F)cc2Cl)CC1 +[O-][n+]1nc2c(I)cnn2c2cc(OCCCl)ccc21 +CN(C)CCCCCNc1c2ccccc2nc2cccc([N+](=O)[O-])c12 +CCOc1cc(F)cc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)c1 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+CC1=CCCC(C)C(C)OC(=O)Cc2c(Cl)c(O)cc(O)c2C1=O +COc1ccc(C2=CCCC(CN3CC=C(c4ccccc4)CC3)C2)cc1 +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCC(F)CC4)c23)c1 +CCC1Cn2nc(-c3ccc(C(F)(F)F)cc3Cl)c3nc(C)cc(c32)N1CC1CC1 +Oc1nc2ccccc2n1CCCN1CCC(c2noc3ccc(F)cc23)CC1 +COc1c(O)c(O)c2oc(-c3ccccc3)cc(=O)c2c1OC +CC(Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Br)c2c(=O)n1-c1cccnc1 +CC1c2[nH]nc(NC(=O)c3ccccc3F)c2CN1C(=O)N1CC2CCCN2CC1Cc1ccccc1 +CCc1ccc(-c2cc(C#CC(C)N(O)C(=O)C(C)C)nn2-c2ccc(OC)cc2)cc1 +CCc1ccc(C(=O)Nc2cccc3c2CCN(C)C3)c(OC)c1 +NC(=O)c1ccc(OCCCN2CCC(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +CCC(C)Oc1ccc(-c2nnc(-c3ccc(CCC(=O)O)cc3C)s2)cc1C#N +Nc1nc2c(nnn2Cc2cccc(F)c2)c2nc(-c3ccco3)nn12 +CC1C(N)CCCN1c1ccncc1Nc1ncc2ccc(-c3c(F)cccc3F)nn12 +CC(O)(CSc1cccc(N)c1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CC(C)CCCC(C)C1CCC2C3=CCC4C(=O)C=CC(=O)C4C3CCC21C +O=C(Cn1c(=O)ccc2ccc(C(F)(F)F)cc21)Nc1scc(Br)c1-c1ncn[nH]1 +Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3ccccc3Cc3ccccc32)cc1 +CCn1nnc(C2OC(n3cnc4c(N)nc(NC(CO)Cc5ccc(OC)cc5)nc43)C(O)C2O)n1 +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)c5cnco5)C4)c3C2)cc1C(F)(F)F +Cc1cc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2cc1-c1cccnc1Cl +COc1cc2c(C)[nH]c(=O)c(Cc3cnc4cccc(OC)c4c3)c2cc1OC +COc1cc(C(=O)N2CCC2c2noc(-c3ccccc3OC(F)(F)F)n2)c(-n2nccn2)cc1C +O=C(c1ccc(O)cc1O)N(Cc1cccnc1)c1ccc(-c2nc3ccc(Cl)cc3cc2CO)cc1 +CCC(C)Cn1c(-c2c(F)cc(F)cc2F)c(Cl)nc(-n2cccn2)c1=O +COc1ccc(CNC(C)=O)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +Cc1ncccc1Oc1ncnc(OC2CC3C=CC(C2)N3C(=O)OC(C)C)c1C +Cn1c(C#N)ccc1-c1cc(F)c2c(c1)C1(CCCC1)C(=O)N2 +CSc1ccccc1CNc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1C(N)=O +CCCCC(NC(=O)OC1CC2CCC1C2)C(=O)C(=O)NC(C)c1ccccc1 +NC(=O)c1cccc2c(NCc3cc(F)cc(Cl)c3)ncnc12 +COC1COC(c2c(NC(=O)c3nc(-c4cc(Cl)ccc4F)sc3N)cnn2C)CCC1N +CS(=O)(=O)Cc1cc(N2CCOCC2)nc(-c2ccc(NC(=O)Nc3ccc(F)cc3)cc2)n1 +COC(=O)C1C(OC(=O)Nc2cccc(N=[N+]=[N-])c2)CC2CCC1N2C +COC(=O)c1ccc(COC(c2ccc(C#N)c(-c3ccccc3C(F)(F)F)c2)c2cncn2C)nc1 +CCn1c2ccccc2c2cc(S(=O)(=O)Nc3ccc(OC)nc3)ccc21 +COc1ccccc1CCn1c(NC(=O)c2ccc(C#N)cc2)nc2cc(N(C)C(=O)C3CCCCC3)ccc21 +O=S(=O)(c1cccc(C(F)(F)F)c1)N1C2Cc3n[nH]cc3C1c1cc(F)c(F)cc12 +CN(Cc1ccccc1)C(=O)c1cc2ccccc2c(-c2ccccc2Cl)n1 +Cc1cc(-c2cccc(Cl)c2C=CC2CC(O)CC(=O)O2)ccc1F +c1ccc2c(CCNc3ccc(Nc4ccncc4)cc3)c[nH]c2c1 +CCN(CC)CCCS(=O)(=O)c1ccc2nc(NC(=O)NC(=O)c3cc(N4CCOCC4)ccc3Cl)sc2c1 +N#Cc1ccc(C(=O)NC2CCCC(n3c(-c4ccccn4)nc4cc(C(N)=O)ccc43)C2)s1 +COCc1nc2c(n1Cc1ccccc1)C(=O)N(C)C1=NC3CCCC3N12 +CC1CCCN1c1cccc(Nc2cc(-c3cccc(CN4CCCC4)c3)nn3ccnc23)n1 +N#CC1(c2ccc(NC(=O)c3cccnc3NCc3ccncc3)cc2)CCCC1 +COc1cc(C(=O)C(=O)N2CCN(C(=O)c3ccccc3)CC2C)ccc1-c1cc(C)no1 +C=CC(=O)Nc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OCCNC(=O)CS(C)(=O)=O +CCc1ccccc1OCCNCCCCN1C(=O)C2CCCN2C1=O +O=C(O)CNC(=O)c1cccc2c1ncn2-c1ccccc1 +COc1cc(CCC(=O)Nc2ccc(C(=O)NO)cc2)ccc1OCc1cccs1 +Cn1c(-c2ccc(CN3CCCC3)cc2)nc2onc(-c3ccccc3Cl)c2c1=O +Cc1ccc2c(OCCN3CCC(Cc4ccc5c(c4F)NC(=O)CO5)CC3)cccc2n1 +CC(C)(C)OC(=O)N(Cc1ccccc1)Cc1ccc(C=CC(=O)NOC2CCCCO2)cc1 +CC(=O)NCc1cccc(-c2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +COCCN(c1cc(OC)cc(OC)c1)c1ccc2ncc(-c3cnn(C)c3)nc2c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3n[nH]c4ccccc34)cc(N3CCN(C)CC3)n2)c1 +CCc1cccc2cc3cccc(C(=O)NCCN(C)C)c3nc12 +Cc1c(CC(=O)O)c2cccnc2n1S(=O)(=O)c1ccc(F)c(Cl)c1 +CCn1nc(Cc2ccccc2)cc1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2cccc(F)c2)CC1 +CN1C(=O)NCC1C(=O)NCc1ccc(F)c(C(F)(F)F)c1 +O=[N+]([O-])c1cccc(-c2cc(-c3cc(Br)ccc3O)n[nH]2)c1 +Cc1noc(C)c1-c1ccc2c(c1)C(CCCN1CCN(C)CC1)(c1ccccc1)C(=O)N2 +COc1cccc(CNCCCNc2ccnc3cc(-c4ccccc4)ccc23)c1O +Nc1ccccc1NC(=O)c1ccc(CNC2=NC(=O)C(Cc3c[nH]c4ccccc34)N2)cc1 +COc1cc(C(=O)c2c[nH]c3c(Cl)c(OC)ccc23)cc(OC)c1OC +COc1ccc(N(C)c2ccc3nc(N)nc(N)c3n2)cc1 +CCC1(O)c2cc3n(c(=O)c2COC(=O)C1OC(C)=O)Cc1c-3nc2ccccc2c1C1CCN(C)CC1 +CN1CCN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)CC1 +O=C1CCC(=O)N1CCCOc1ccc(C2Oc3cc(O)ccc3C3=C2c2ccc(O)cc2OCC3)cc1 +O=C(COc1ccccc1-c1ncc[nH]1)NCC(O)CN1CCc2ccccc2C1 +CC(=O)N1CC2C=C(c3cnc(NCc4ccc5c(c4)OCC5)c(C(=O)NCC4COc5ccccc5O4)c3)CC1CC2 +CCCCNc1nc(NCCCCCCC(=O)NO)c2ncn(Cc3ccccc3)c2n1 +CCOC(=O)c1c[nH]c2ncnc(-c3cccc(Cl)c3)c12 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCn1c([N+](=O)[O-])cnc1C +NC(=O)CCn1ccc2c(Nc3ccc(OC(F)(F)F)cc3)ncnc21 +Cc1cc(C)c(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Cl)c(C(=O)C2CC2)c1 +CCc1cc2c(cc1-c1cnn(C3CCOC3)c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CCCC(CC)Nc1nc(C)nc2c1ncn2-c1ccc(C(C)C)cc1Br +Cc1oc(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)Nc2ccccc2)nc1C(=O)O +CC(C)(C)CN(Cc1ccc(C=CCN2CCC(N3CCCCC3)CC2)cc1)c1ccnc(C#N)n1 +COc1ccc(Cn2c(=O)n3ncnc3c3c4c(sc32)CN(CC2CCOCC2)CC4)cc1 +Cc1ccn2cc(C3CC3c3cc(-n4nc(C)nc4C)nc(C)n3)nc2c1 +C=C(C)c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)c(OC)c1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cc4ccccc4o3)cc2)no1 +COc1cccc(CC(=O)Nc2ccc3cc(C(=O)NO)sc3c2)c1 +CC(C)CS(=O)(=O)N1CCC(NC(c2cnccn2)c2ccc(F)cc2F)CC1 +CNc1cc(-c2ccccc2)cc(C(Cc2ccccc2)NC(=O)C2CCC(CN)CC2)n1 +O=C(NC1CCC(O)CC1)c1cnn2ccc(NC3CCc4ccccc43)nc12 +CCCCNC(=O)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1C(=O)NCc1cccnc1 +CCc1ccccc1-n1c(Cn2nc(-c3cc(O)cc(F)c3)c3c(N)ncnc32)cc2cccc(C)c2c1=O +Cc1nc(C2CC2c2nc3ccc(Cl)cc3[nH]2)cc(-n2nc(C)nc2C)n1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCc1ccccc1 +CC(C)(C)c1cc(NC(=O)c2ccc(F)c(Nc3ncnc4cnc(NC5CCOC5)nc34)c2)no1 +Fc1cccc(F)c1-c1ccc2[nH]nc(-c3cncc(OC4CNCCC45CC5)n3)c2c1 +O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCNCC1 +NS(=O)(=O)C1OC(COP(=O)(O)O)C(O)C(O)C1O +O=c1oc(-c2cccc([N+](=O)[O-])c2)ns1 +CCCS(=O)(=O)N1CC2C(C1)C2(CNC(=O)c1ccc(Cl)cc1Cl)CC1CC1 +CC(C)N1CC(C(=O)N2CCN(c3ccccc3CN3CCC(N)CC3)CC2)C(c2ccc(Cl)cc2)C1 +CCOc1ccc(C(=Cc2cc(OC)c(OC)c(OC)c2)C(=O)N2CCC=CC2=O)cc1 +CC1(C)Oc2cc(C#Cc3ccccc3C(F)(F)F)ccc2-c2nc(-c3c(Cl)cncc3Cl)[nH]c21 +O=C(CCCCc1cccs1)Nc1ccc2c(c1)CC(C(=O)O)OC2 +COC1CCC2(CC1)Cc1ccc(C(C)C)cc1C21N=C(N)N(C(C)C)C1=O +CCc1nc(N)nc(N)c1-c1ccc(Cl)c(N=NN(CCOC(C)=O)Cc2ccc3ccccc3c2)c1 +O=c1[nH]c2ccccc2c(=O)n1CCN1CCN(C2CC(c3ccc(F)cc3)c3ccccc32)CC1 +NS(=O)(=O)NCCCCC(NC(=O)OCc1ccccc1)c1nc2ccccc2[nH]1 +Cc1[nH]c2ncccc2c1C1CCN(C(=O)C(C)(C)c2ccc(Cl)cc2)C1 +CCC(=O)c1oc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c1N +CNc1cc2c(c3ccccc13)C(CCl)CN2C(=O)c1cc2cc(OC)c(OC)c(OC)c2[nH]1 +CN1CCc2c(c3ccc(-n4ccc(-c5ccc(F)cc5)cc4=O)cc3n2C)C1 +CCOCC(COCC)Oc1cc(F)ccc1Nc1ncnc2sc(C(N)=O)c(C)c12 +N=C(N)c1cccc(Oc2cc(O)ccc2NC(=O)c2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +O=C(c1ccc(S(=O)(=O)Cc2ccccc2)cc1)N(CCC1CCN(Cc2ccccc2)CC1)c1ccccc1 +CN(c1ccccc1)c1cc[n+](Cc2cccc(-c3cccc(C[n+]4ccc(N(C)c5ccccc5)cc4)c3)c2)cc1 +Cc1cccc(Oc2c(C(=O)N3CCNCC3)c3ccccc3n2-c2ccccc2)c1 +CC(NC1=CC(=O)NCC1)c1ccc(Nc2ncc3cc(-c4ccncc4)ccc3n2)cc1 +Cc1cccc(C#CC=C2CCN(c3ccccc3)CC2)n1 +CCC1(CC(=O)O)CCC(Cc2ccccc2)c2c1[nH]c1ccccc21 +CNC(=O)c1nccnc1NCC(=O)N1CCC(Oc2c(Cl)cccc2Cl)CC1 +O=C(O)CC(NS(=O)(=O)c1cccc(-c2cccc(Nc3ncc[nH]3)c2)c1)c1ccccc1 +CC(C)N(C(=O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1)C(C)C +O=C(Cc1ccc(F)cc1)Nc1ccc2c(c1)C(=O)N(O)C(=O)C2 +Cc1ncc(C)n2nc(CCc3nc(N4CCC(F)(F)C4)nn3C)nc12 +COc1cccc(-c2cn(-c3ccc(OCCNCCO)cc3)c3ncnc(N)c23)c1 +CCC(Sc1nc(-c2ccc(Cl)cc2)c(C#N)c(=O)[nH]1)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1ccc(C(=O)NCCN2CCOCC2)cc1 +CCn1cc(C(=O)O)c(=O)c2ccc(Oc3ccnc(Nc4ccc(C#N)cc4)n3)cc21 +COc1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1S(C)(=O)=O +Cc1ccncc1C1=CC=C2C3CC=C4CC(O)CCC4(C)C3CCC12C +O=C(NCC(c1ccccc1)c1ccnnc1)c1cccc(Cl)c1Cl +CC(C)(CC(=O)O)Cc1nc2ccccc2n1Cc1ccc(Br)cc1 +CCCNc1ncc(-c2ccc(OCC)cc2)cc1C(=O)c1ccc(F)cc1 +CC(=O)Nc1ccc(S(=O)(=O)NNc2ccc(Cl)c(Cl)c2)cc1 +COCCn1cc(-c2ccc(O)cc2)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O +O=C1NC(c2ccccc2)(C2CC2)C(=O)N1CCCN1CCN(c2ccccc2)CC1 +CC(C)c1nn(-c2ccc(C(N)=O)c(N(O)C3CCCCC3)c2)c2nccc(-n3cnc(-c4ccncc4)c3)c12 +N=C(N)NCCCC1NC(CNC(=O)c2ccc(Cl)c(Cl)c2)CCN(CC(c2ccccc2)c2ccccc2)C1=O +COC1(c2csc(Sc3ccc4c(c3)OCCC4=NOCC#N)c2)CCOCC1 +OCc1cc(-c2ccccc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1 +CCN(CC)CCCOc1ccc2nc3n(c(=O)c2c1)CCc1ccccc1-3 +Cc1onc2c1CC1(CC2)Cc2ccc(C#CC3CC3)cc2C12N=C(N)N(C)C2=O +CC(F)(F)c1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 +CCCCN(C(=O)c1ccc(C(F)(F)F)cc1)c1nnc(-c2cccc3[nH]cc(Cl)c23)s1 +CC(C)(C)C(=O)NC(Cc1ccc(NS(=O)(=O)O)cc1)c1nc(-c2ccc(-c3ccccc3)cc2)cs1 +NC(=S)NN=C(COc1ccc(F)cc1)c1ccc(Br)cc1 +CC(NS(=O)(=O)C(F)(F)F)c1ccc(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)cc1 +COc1cc(C(F)(F)F)ccc1N1C(=O)COc2cc(S(=O)(=O)Nc3ncns3)ccc21 +O=C(CCN1CCCCC1)Nc1ccc2sc3ccccc3c(=O)c2n1 +CCCCn1c(=O)c(C(=O)Nc2nnc(C(C)C)s2)c(O)c2ccccc21 +O=C(O)C1CN(Cc2ccc(-c3noc(-c4ccc(C5CCC(F)(F)C5)cc4)n3)cc2)C1 +COc1ccc(N=c2oc3cccc(O)c3cc2C(=O)Nc2ccccn2)cc1 +CC(=O)Nc1nc2c(Oc3cc(C4=CCC(C(F)(F)F)CC4)ncn3)cccc2s1 +CC1=C(Sc2ccccc2)C(COCc2ccccc2)C(=O)NC1=O +O=C(O)CCCn1cc(C(=O)O)c(=O)c2c(C=Cc3ccc(OCCCCOc4ccccc4)cc3)cccc21 +CN(C)CC(COc1ccccc1CCc1cccc(Cl)c1)OC(=O)CCC(=O)O +CC(CN1CCOCC1)n1cc(C(=O)c2cccc3ccccc23)c2ccccc21 +O=C(CCCCN1C2CCCC1c1c([nH]c3ccc(F)cc13)C2)c1ccccc1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2CCNc1ccccc1 +CN(C)C1(c2ccccc2)CCC(NC(=O)Cc2ccccc2)CC1 +Cc1ccc(S(=O)(=O)NCc2cccn3c(=O)cc(N4CCOCC4)nc23)cc1 +CCN1C(=O)c2c(nc(OC)n2Cc2ccc(OC)c(Br)c2)N2C1=NC1CCCC12 +O=C1c2ccccc2C2=Nc3ccccc3SC(c3ccc(Cl)cc3)C12 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCn4ccnc4C3)[nH]c12 +Oc1c(-n2ccnn2)cnn1-c1cc(N2CCOCC2)ncn1 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+N#CC1(NC(=O)C2CCCCC2C(=O)N2CCN(c3nc(-c4ccccc4)cs3)CC2)CC1 +O=C(O)c1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O +CN1CCN(c2ccc3[nH]c(-c4c(N)c5cc(F)c(F)cc5[nH]c4=O)nc3c2)CC1 +NC(=O)c1ccc(NC2CCCCC2N)cc1Nc1cccc(-c2cccc(F)c2)n1 +COc1ccc(S(=O)(=O)n2ccc3cccc(-c4ccc(C#N)cc4)c32)cc1 +CCc1nn(Cc2csc(C(C)C)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)CC5)ccn34)c12 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccc(Oc2cc(NC(=O)C3CC3)ncn2)c(F)c1 +CC(C)CN(C)C(=O)C1CCN(Cc2cccc(NC(=O)c3cncc(F)c3)c2)CC1 +COC1C(CO)OC(n2c3ccccc3c3c4c(c5c6ccccc6[nH]c5c32)C(=O)N(N)C4=O)C(O)C1O +CN(C)CCCn1c(=O)c2ccc3c4c(nn3CCN(C)C)-c3ccccc3-n(c1=O)c24 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c(C=NOC(C)(C)C)c3ccccc3[n+]([O-])c2-1 +CCCOc1ccc(-c2ccc(NC(=O)N3CCCC3C(=O)N3CCC4C3C(C)C(=O)N4C(=O)C3CC3)cc2)cc1 +COc1cccc(CN(c2sc3ccccc3c2Br)S(=O)(=O)c2ccccc2)c1 +CN1C(=O)C2(CC1c1ccc(OCc3cc(-c4ccccc4)nc4ccccc34)c(F)c1)CC2C(=O)NO +CN(C)C(=O)n1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccccc3)cc21 +Clc1ccc(-c2n[nH]c(N3CCCC4CCCCC43)c2-c2ccncc2)cc1 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+CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCc4ccccn4)cc3)oc2c1 +Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2CC1CCNCC1 +CC(O)CN(Cc1cccc2ccccc12)c1cc(N2CCOCC2)nc(=O)[nH]1 +CCSCc1ccc(-c2sc3cc(O)ccc3c2C(=O)c2ccc(OCCN3CCCCC3)cc2)cc1 +CCN(C)c1cc(C(F)(F)F)cc(COCC2(c3ccc(F)cc3)CCN(C)CC2)n1 +Cc1nc(N)nc(-c2cc(C(C)(C)O)cnc2Nc2cncc(F)c2)n1 +COC(=O)c1cccc(Cn2cnc3c(-c4ccco4)nc(N)nc32)c1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-n3ccnc3)ccc21 +Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ccc(-c3ccc(C(=O)O)cc3)cc1)C(=O)N2c1cc(O)ncn1 +CS(=O)(=O)CCC1OCCC2(S(=O)(=O)c3ccc(F)c(F)c3)c3c(F)ccc(F)c3OCC12 +Cc1c(OC2CCCCC2)cccc1-c1ccc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)nc1C(=O)O +CCCOC(=O)c1cc(N2C(=O)C3=C(CCCC3)C2=O)ccc1Cl +O=C(CN(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)NO +CC1CCc2ccccc2N1C(=O)c1cc(Cl)c(O)cc1O +CCCCNc1ncc(-c2ccc(S(=O)(=O)N3CCOCC3)cn2)c(NC2CCC(O)CC2)n1 +COc1ccc(-c2cc3c(cc2C2CCN(C)CC2C)N2C(=NNC(=O)C2C)CO3)cc1 +COc1ccc(-c2ccc3c(c2)c(C#N)cn3-c2ccc(C(=O)O)cc2)cc1 +O=C(NC1CCCCC1C(=O)NO)c1ccc(Cn2c(C(F)(F)F)nc3ccccc32)nc1 +Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccc3c(c2)OCO3)c1Br +CC1(C)OC(=O)C(Oc2cccc3cnccc23)=C1c1ccc(S(C)(=O)=O)cc1 +O=C(OC1CCc2ccccc21)N1CCC2(CC1)C(=O)NCN2c1ccccc1 +COc1cc2c(c(OC)c1OC)CC(Sc1nc3cc([N+](=O)[O-])ccc3[nH]1)C2=NN=C(N)N +O=C1N=C(c2ccccc2)SC1=Cc1c2ccccc2cc2ccccc12 +CC(C)(C)COc1ccc2c(c1)C1(COC(N)=N1)c1cc(-c3ccncc3)ccc1O2 +O=C(C1CCCN(c2ccc3nc(COc4ccc(Cl)cc4)[nH]c3n2)C1)N1CCCC1 +CCN(CCN(C)c1nc2ccccc2o1)C(=O)c1cc(C)ccc1-n1nccn1 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCOC5(CC5)C4)ncn3)c2c1 +CNC(=O)CCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1 +CCCCc1nnc(SCc2ccc(OC)cc2)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +Cc1cc(N)nc(CC2CNCC2N(C)CCNCCc2cccc(F)c2)c1 +Cc1cn2cc(C(N)=O)cc2c(C#Cc2ccsc2)n1 +O=C(O)C(Cc1ccc(C=Cc2ccc([N+](=O)[O-])cc2)cc1)NC(=O)C1CCC(=O)N1Cc1ccccc1 +CCN(CC)c1ccc(-c2sc(Nc3ccccc3)n[n+]2-c2ccc(F)cc2)cc1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(N3CCN(CC4CCN(C)CC4)CC3)nc12 +COc1cc(OC)c2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc2c1 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+O=C(c1ncc(-c2ccccn2)o1)C1Cc2ccc(Oc3ccccc3)cc2C1 +CCCCn1c(CNc2ccc(C(=N)N)cc2F)nc2cc(C(=O)N(CCC(=O)O)c3ccc(F)c(Cl)c3)ccc21 +CN1CCN(C2(c3nc(-c4cnc(N)c(-n5nnc6ccccc65)n4)nn3C)CC2)CC1 +COc1cccc(C(Nc2ccccn2)c2oc(CO)cc(=O)c2O)c1 +COc1cc(N2CC(=O)N(c3ccc(Oc4ccccc4)cc3)C2=O)ccc1OCCN1CCCC1 +CC(NC(=O)C(O)C(O)C(=O)N1CCCC1c1csc(N2CCCCC2)n1)c1ccc(-n2cccn2)cc1 +COc1ccc(-c2cc(-c3ccco3)nc(N)c2C#N)cc1 +O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(O)c1 +COc1cccc(-n2ncc3c(NN=Cc4ccc(N)cc4)ncnc32)c1 +Cc1nc2c(NCc3ccncc3)cc(Cl)nn2c1-c1cccc(S(=O)(=O)N(C)C)c1 +COc1cccc2c1ncc1c(=O)n(-c3ccc4c(c3)OCO4)c(=O)n(C3CCCC3)c12 +Cc1nn(C)cc1CC(=O)Nc1cncc(C(=O)c2cn(C(C)(C)C)c3ncncc23)c1 +Cc1cc(C#N)cnc1C(=O)Nc1cnc(F)c(C2(CF)CC(C(F)(F)F)OC(N)=N2)c1 +CC(Nc1ncnc2[nH]c(-c3ccc(NCCCCCC(=O)NO)cc3)cc12)c1ccccc1 +COc1cc2ncc(C(N)=O)c(Nc3cccc(C)c3)c2cc1OC +Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(N2CCC3(CCNC3)CC2)nc1 +Cc1nc(O)c2cc(CN(C)c3cc(F)c(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c3)ccc2n1 +CC1=CC2Cc3[nH]c(=O)ccc3C3(C1)C2CCCN3C(=O)CN(C)CCCCCCCCCCCCN(C)Cc1ccc(F)cc1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(C)c3c2)c1F +COc1cc(C2CC(c3ccc(C)cc3)=NN2C(=O)CO)cc(OC)c1OC +CC1CC=C(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +CC(c1ccc(-c2ccc(=O)n(C(C)C)c2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2)OC1=O +CCCS(=O)(=O)Nc1ccc(OC2CCOCC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +CC(Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2ccc(C(F)(F)F)nn2)CC1)C(F)(F)F +CN1C(=O)C(NC(=O)CCc2cccc(Cl)c2Cl)N=C(c2ccc(C(N)=O)cc2)c2ccccc21 +NS(=O)(=O)c1ccc(NSC(=S)N2CCOCC2)c(Cl)c1 +Cc1cccc(Cl)c1S(=O)(=O)N1CCCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)C1 +COc1cc(C2Nc3ccc(C(=N)N)cc3C3c4ccccc4CC23)c(-c2ccc(C(=O)O)cc2)cc1O +NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cccc(Cl)c1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(C4(C)NC(=O)NC4=O)nc3)NC(=O)NC1=O)C2 +CN(C)CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(OC(F)F)cc2)CC3)n1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc(C(=O)N(C)C)c2)n1 +Cc1cc2ccccc2nc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 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+CC1CN(CCC(O)c2csc3ccc(F)cc23)CCN1c1cccc2c1OCO2 +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCCC1C(N)=O +COc1ccc(-c2cnnn2-c2cc(OC)c(OC)c(OC)c2)cc1[N+](=O)[O-] +CC(C)CC1C(=O)NC(C(=O)NC(C)C(=O)N2CCOCC2)CCCCNC(=O)OCCCC1C(=O)NO +CN(C)CCCCNC(=O)c1cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(Cl)c2[nH]1 +O=C(NCC(NC(=O)c1c(Cl)cc(CCC(O)c2cccc(O)c2)cc1Cl)C(=O)O)c1cccs1 +CC(C)(C)COc1ncnc2[nH]cc(C=CC(N)=O)c12 +Cc1noc(C)c1-c1ccc2c(c1)C(c1ccccc1)(N1CCC(N)C1)C(=O)N2 +COc1ccc2c(c1)C(=O)C(c1ccc(C)cc1)=[N+]2[O-] +CC(CC(O)N1CCCC(Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(-c2nccn2C)c1 +Cc1cnc(NC(=O)C2(C)CC3c4ccccc4C2c2ccccc23)s1 +O=C(Nc1ccc(OC2CCN(CC3CCCC3)CC2)cc1)N1Cc2ccncc2C1 +Oc1nc2ccc(C#CCN3CCC(O)(Cc4ccc(F)cc4)CC3)cc2s1 +CCCCN(CCCC)CCCOc1ccc(S(=O)(=O)c2c(CC)cn3ccccc23)cc1 +CCc1nn(Cc2ccc(OCc3cccc(C)c3)cc2)c(CC)c1CC(=O)O +Cc1ccc(C2(O)CCC(N3CCC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cn1 +CCc1nccc(-c2ccc(C(=O)N3CCN(C4CCCC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +Cc1ccc(S(=O)(=O)N2CCN(C)C(=O)C2CC(=O)NC2CCCc3cc(CN4CCCCC4)ccc32)cc1 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+Cn1cc(-c2ccc3cn[nH]c3c2)c(-c2ccncc2)n1 +Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)CCCC(=O)O)O2)c(=O)[nH]c1=O +CCN(CC(=O)N(C)C)Cc1ccc(CCNC(=O)c2ccc(-c3ccc(Cl)cc3)cc2)cc1 +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc(N(C)C)cc2)cc1 +CCOC(=O)c1c(-c2cccc(Oc3ccccc3)c2)[nH]c2cc(O)ccc2c1=O +CC(C)N(C)C(=O)c1nc(-c2ccccc2Cl)c2ccccc2n1 +Cc1c(Cc2ccc(F)c(C(=O)N3CCN(C(=O)C4(NCC5CC5)CCCC4)CC3)c2)n[nH]c(=O)c1C +O=CC(Cc1ccccc1)NC(=O)c1ccccc1C=Cc1ccccc1 +CN1N=C2CCN(C(=O)C(COCc3ccc(F)c(F)c3)NC(=O)C(C)(C)N)CC2(Cc2ccccc2)C1=O +COC=C(C(=O)OC)c1ccccc1COc1nc(Nc2ccc(Cl)cc2Cl)nc(C(F)(F)F)c1C +COc1cc(OCc2nsc(-c3ccccc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C1C=C2N(C(=O)c3cc4cc(Cl)ccc4[nH]3)CC3CC23c2ccccc21 +COc1cc2c(cc1OC)C(c1ccnc(-n3nc(-c4cccnc4)c4ccccc4c3=O)c1)=NC(CO)C2 +CCCCCCCCCC(=O)OCc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F +Cc1cc(C)nc(N2CC3CN(C(=O)c4c(C)cccc4C)CC3C2)n1 +Fc1ccc(CN(CCC(F)(F)F)Cc2sc(Nc3c(Cl)cc(Cl)cc3Cl)nc2C(F)(F)F)cc1 +COc1cccc(Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1Cl 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+CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 +N#Cc1ccc(Cn2cncc2CNC2CCN(C(=O)c3cncc(Br)c3)C2)cc1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)nc31)CN1CCC2CC1 +N=C(N)C1CCCC(NC(=O)CN2CCCC(NS(=O)(=O)c3cccc4ccccc34)C2=O)C1O +Cc1nc2ccc(Br)cc2c(-c2ccccc2)c1C(=O)O +CCOC(=O)c1c(-c2ccc(-c3ccc(OC(F)(F)F)cc3)cn2)[nH]c2ccccc2c1=O +CC(F)c1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(=O)c1ccc(OC(C)C)c(-n2c(CN3CCN(C(=O)COc4ccc(Cl)cc4)CC3)nc3ccccc3c2=O)c1 +Cc1cc(C(C)C)nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)n1 +CCCN1CCC(CNC(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)(C(=O)NO)CC1 +Cc1cccc(-c2csc(N3CCC4(C(=O)O)CC4C3)n2)c1OCc1ccc2c(c1C)CCN(C1CCOCC1)CC2 +C=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1CCC)C(C)(C)CCC2(C)C +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(Cc2cccc3cc[nH]c23)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2ccc(N)nc2)c1F +O=C(c1ccc(Br)cc1)N1CCN(C(=O)c2ccc(-c3nccs3)cc2)CC1 +COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C(=O)N2 +O=C(CN1CCCC(c2nc3ccccc3n2Cc2ccc(F)cc2)C1)N1CCCCC1 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+N#Cc1cc(-c2ccnc(Nc3ccc(CN4CCNC(=O)C4)nc3)n2)cnc1N1CCC(F)C1 +CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NC(CO)CC(C)C +CCCCCC(O)C=CC1C=CC(=O)C1CCCCCCC(=O)O +CN(C)C(=O)c1ccc(Nc2cc3c(-c4cnn(C)c4)cccc3cn2)c(Cl)c1 +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccc(C)cc2)c2ccc(Cl)c(Cl)c2)CC1 +CCCCn1cc2c(nc(NC(=O)Nc3ccccc3Cl)n3nc(-c4ccco4)nc23)n1 +COc1cc(-c2cc(=O)c3cc(Cl)cc(Cl)c3o2)ccc1O +COc1ccc2c(c1)OC(C)(C)c1cn(CNC(=O)CN3CCN(c4ccccc4OC)CC3)nc1-2 +CCC(C)C(CNC(C(=O)NC(CCO)C(=O)O)C(C)CC)NC(=O)C(N)CS +NS(=O)(=O)c1ccc(Nc2nc(=O)[nH]c(=O)[nH]2)cc1 +O=C(C1=C(O)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccc(Cl)cc1 +CC1(C(=O)N(CC#N)Cc2ccc(Cl)cc2)CCN1C(=O)Cc1csc2ccccc12 +Clc1ccc(Nc2nccc(-c3ccc4c(c3)OCO4)n2)cc1 +CNCC(Nc1ncnc2c1=CCCC=2C(N)=O)c1cccc(NC(=O)c2ccc(C(F)(F)F)cc2)c1 +COc1ccc2c(c1)CN(c1ccc(N(C)C)cc1)C2=O +CN1CC(C(=O)NCc2ccccc2-c2ccccc2)=C(O)C1=O +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(C2CCCCC2)cc1 +CC1CN(CCC(=O)N(Cc2ccc(-c3ccccc3)cc2)C(Cc2ccccc2)C(=O)O)CCC1(C)c1cccc(O)c1 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+O=C(NCCc1nc(-c2ccncc2)n[nH]1)C12CC3CC(CC(C3)C1)C2 +CCC(C)N(CC(=O)Nc1cc(F)cc(F)c1)C(=O)c1ccc(-c2ccccn2)cc1 +O=c1[nH]c(=O)n(C2CC(O)C(COP(=O)(O)O)O2)cc1Cl +CCCN1CCC(Cc2ccc(F)cc2)CC1CCCNC(=O)Nc1cccc(C(C)=O)c1 +COc1ccc2ccn(CCn3cc(NC(=O)c4ncoc4-c4cccc(C)c4)cn3)c2c1 +CCCn1cc(C(=O)c2cccc3ccc(C)cc23)c2ccccc21 +Cn1c2cc(OCCCN3CCCC3)c(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +CCOc1cc2ncnc(Nc3ccc4c(cnn4Cc4ccccc4)c3)c2cc1NC(=O)C=CCN1CCN(C)CC1 +COc1ccc(NCc2cncn2C)c(C(=O)NC2CCN(Cc3ccc4c(c3)OCO4)CC2)c1 +COc1cc2c(N)nc(N3CCN(C(=O)CC4CCCCN4)CC3c3ccccc3)nc2c(F)c1OC +Cc1ccc(N2CCc3ncnc(NC(CO)c4cccnc4)c3C2)nc1 +CCC(CNCc1cccc2[nH]ccc12)C(=O)N(Cc1cc(Cl)c2c(c1)OCCCO2)CC(C)C +CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2cccc(Cl)c2)CC1 +COc1cc(-c2cc(NC(=O)Nc3ccc(OCCCN4CCOCC4)cc3)cc(OC)c2OC)ccc1C(C)=NO +Cc1cccc(C)c1N(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)c1ncccn1 +COc1cc2oc(C(=O)NC3CCN(Cc4ccc5c(c4)OCO5)CC3)cc(=O)c2cc1F +N=C(N)c1ccc(-c2ccc(N3CCN(CC(=O)O)CC3)cc2)cc1 +N=C(N)Nc1ccc(CNC(=O)N2CCN(C(=O)NC3CCC(c4ccccc4)(c4ccccc4)CC3)CC2)cc1 +OCC(O)CN1CCC(c2cc3c(-c4cncc(NCc5ccccc5)n4)ccnc3[nH]2)CC1 +Fc1ccc(NC(=S)c2ccco2)cc1-c1nc2ncccc2o1 +O=S(=O)(Nc1ncns1)c1cc(F)c(Oc2ccc(C(F)(F)F)cc2C2=CCNCC2)cc1F +CCN1CCN(C(=O)c2ccc(NCc3ccc(-c4cccc(F)c4C(=O)OC)cc3F)nc2)CC1 +Cc1cc(OC(F)F)cnc1C(=O)Nc1ccc(F)c(C2(C(F)F)COCC(N)=N2)c1 +O=C(NC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1)c1ccc2cn[nH]c2c1 +COc1ccc(CCNCC(O)COc2ccc(Cc3nc(C(C)=O)c[nH]3)cc2)cc1OC +N#CCC1(n2cc(C(N)=O)c(Nc3cncc(F)c3)n2)CCN(C(=O)OCC(F)F)CC1 +Cn1c(=O)c2c(nc3n2CCN3C2CCCCCCC2)n(C)c1=O +Cc1ccc(CNCC2(F)CCN(C(=O)c3cc4ccccn4n3)CC2)nc1 +COc1ccc2c(c1)CCN1C(=O)C3CCCC(C21)N3S(=O)(=O)Nc1ccc(F)c(F)c1 +O=C(c1ccc2cc(OCCCN3CCCCC3)ccc2c1)N1CCC(CO)CC1 +O=C(NC1CCC(CCN2CCc3sccc3C2)CC1)c1cc2ccccc2[nH]1 +Cc1ccc(S(=O)(=O)c2c(C(=O)NNCCO)[nH]c3ccc(Cl)cc23)cc1 +CC(C)(C)OC(=O)N1CCC(C(NS(=O)(=O)c2ccc(-c3ccccn3)s2)C(=O)O)CC1 +O=C(NO)c1ccc(-c2ccn(CCNCc3ccc4occc4c3)n2)s1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCC(NCc2ccccc2Cl)CC1 +CCc1nc2cc(O)ccc2c(Oc2ccc(C=CC(=O)O)cc2)c1-c1ccccc1 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+O=C(Nc1ccc2c(c1)OCO2)C1C(c2ccc(Cl)c(Cl)c2)OC2(C(=O)c3ccccc3C2=O)C1C(=O)O +CCCCOc1ccc(-c2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)cc1Cl +O=c1cc(OCc2ccc(F)cn2)ccn1-c1ccc2c3c([nH]c2c1)CCNCC3 +CC(C)c1cc(CNc2nc(Nc3cc(C(C)C)[nH]n3)cc(N3CCOCC3)n2)on1 +O=C1N(c2ccc(OCc3ccccn3)nc2)CCN1c1ccc(Cl)c(Cl)c1 +Nc1nc(NCCNc2ncc(NC(=O)CCCN3CCOCC3)c(-c3ccc(Cl)cc3Cl)n2)ccc1[N+](=O)[O-] +Cc1cccc(N2CCCCCC2)c1CNC(N)=NC(=O)c1ccc(CC(N)C(=O)O)cc1 +O=C(c1ccc(Nc2nc3ccccc3n3nnnc23)cc1)N1CCN(C2CCOCC2)CC1 +CSc1nc(-c2ccc(OC(F)(F)F)cc2)nn1C(=O)N(C)c1ccccc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC(N)C(O)CC1 +CCN(CC)c1c(NC(Cc2ccc(-c3ccccc3OC)cc2)C(=O)O)c(=O)c1=O +NCC1CN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)C1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)cn3)c2)c2cnc(N)nc21 +O=C(c1ccc2[nH]ccc2c1)C1(Cc2ccccc2)CCCCNC1 +COc1cc(C(=O)NCCN(C)C)cc(OC)c1-c1cc2c(NC(C)c3ccccc3)ncnc2s1 +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NCc1cccc(F)c1F)CC2 +COc1ccc(CNC(=O)CN(C(=O)c2cc3ccccc3[nH]2)C(C(=O)NC(C)(C)C)c2ccc(OC)cc2)cc1 +CC(C)N(C)C(=O)Cn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +OC(COc1ccc2[nH]c(=S)[nH]c2c1)CN1CCN(c2ccc(Cl)cc2)CC1 +Clc1ccc(CN(Cc2ccc(Cl)s2)n2ccnc2)c(Cl)c1 +COCC(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3cccc(C(F)(F)F)n3)c2)CC1 +CS(=O)(=O)N1CCN(c2ccc(N3CCN(C(=O)NC4C5CC6CC4CC(O)(C6)C5)c4ccccc43)nc2)CC1 +CCN(CC)CCN(C)C(=O)c1ccc2c(c1)-c1nc(N)nc(-c3ccccc3)c1C2=O +Cc1cc(COc2ccc(NC(=O)C3CCN(C(=O)OC4CC4)CC3C(=O)NO)cc2)c2ccccc2n1 +N#Cc1cc(-c2ccoc2)c2ccc(OCc3cncc(C4(O)CCOCC4)c3)cc2c1 +COc1cc(C=CC(=O)NCCCCCCNc2c3c(nc4ccccc24)CCCC3)ccc1OCCO[N+](=O)[O-] +CC1CCC(=NNc2nc(-c3ccc(F)cc3)cs2)CC1 +COc1cccc2c1C1CCCN(C(=O)c3ccc4nc[nH]c4c3)C1CC2 +Nc1n[nH]c2cccc(-c3cccc(NC(=O)Nc4ccccc4F)c3)c12 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCS(=O)(=O)CC4)cc3OC)ncc2C(F)(F)F)c1 +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCc3ccccc3C2)C1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCC3=Cc4c(cnn4-c4ccc(F)cc4)CC3(CN3CCCCC3)C2)cc1 +Cn1c(CN2CCN(c3ncc(C(F)(F)F)cc3Cl)CC2)nc2ccncc21 +CC(C)C1NC(=O)C(Cc2ccc(O)cc2)NCCOc2ccccc2CCCNC(=O)C(CCN)NC1=O 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+N#CC1CC(F)CN1C(=O)C(N)Cc1ccc(OCc2ccccc2)cc1 +NS(=O)(=O)c1ccc(N2CCN=C2c2ccc(Cl)c(Cl)c2)cc1 +COc1cc(-c2[nH]c(-c3ccoc3)nc2-c2ccc(N(C)C)cc2)cc(OC)c1OC +Cc1c(Sc2ccc(Cl)cc2)c2c(NS(C)(=O)=O)cccc2n1CC(=O)O +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N4CCC(C)(C)C4)n3)C2)cc1 +O=C(c1ccc(F)nc1)N1CCCC1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +N#CC1CN(c2cnc(C(=O)Nc3csc(-c4nncn4C4CC4)n3)cc2-n2cnc(C3CC3)c2)C1 +COc1cc(Nc2c(C#N)cnc3cc(-c4cc(CN5CCC(O)CC5)cs4)ccc23)c(Cl)cc1Cl +O=C1OCC2=C1C(c1ccc(F)c(Br)c1)C1=C(CCCS1(=O)=O)N2 +CCCNC(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +CCCCCCCCCCCCn1nnc(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccc(F)cc2)n1 +Clc1cccc(N2CCN(CCCCN3CC4CCCN4C3)CC2)c1 +COc1cc(C=Cc2ccc(N(C)C)c(N)c2)cc(OC)c1OC +CCCOc1cc(CN2CCN(C)CC2)cc(-c2ccc(S(=O)(=O)Nc3c(C)nn(C)c3C)cc2)c1 +CC1=C(C)C(=O)C(CCC(C)(O)CCCC(C)CCCC(C)CCCC(C)C)=C(C)C1=O +COc1ccc2cc1COCC=CCOCc1cccc(c1)-c1ccnc(n1)N2 +COc1ccc(-c2c[nH]c3ncc(-c4ccc(OCCN5CCOCC5)c(N)c4)cc23)cc1OC +COc1cc(N2CCC(N(C)C)C2)c2[nH]c(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1 +CCCN1CCC(N2CC(NC3CCN(CCc4ccccc4)CC3)CC2C(=O)NCCc2ccc3c(c2)OCO3)CC1 +c1ccc(Oc2ccc(CN3CCC(c4c[nH]c5ncccc45)CC3)cc2)cc1 +Cc1cc(C)c(-c2ccc(C(=O)N(C)O)cc2)c(C)c1 +COc1ccc(N2C(=O)c3ccc(C(=O)NCCCN4CCN(c5ccccc5OC(C)C)CC4)cc3C2=O)cc1 +CC(C)(C)OC(=O)N1CCC(n2ncc3c(Oc4cc(F)c(F)cc4F)ncnc32)CC1 +COc1cccc(C=CC(=O)c2ccc(Nc3ncnc4cc(OC)c(OC)cc34)cc2)c1 +O=C(Nc1ccc(F)cc1)c1ccc(SCc2cc(OC(F)(F)F)ccc2O)nc1 +CCN1CCC(N(C(=O)NCc2ccc(F)cc2)c2ccc(CO)cc2)CC1 +N#Cc1cc(Cl)c(C(=O)Nc2ccnc(NC(=O)C3CC3)c2)c(Cl)c1 +CC(=O)N(C)CC1CCC(Nc2nc(Nc3ccc(Cl)cc3)c3ccccc3n2)CC1 +COc1ccc(CC2(O)CCC3C4CCc5cc(OS(N)(=O)=O)ccc5C4CCC32C)cc1 +FC(F)(F)c1ccc(C=CCOCC2CCN(Cc3ccccc3)CC2)cc1 +O=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1nc2ccccc2[nH]1 +NC(CC(=O)N1CCCNC(=O)C1)Cc1cc(F)c(F)cc1F +Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(CN4CCOCC4)nc3)cc(N(C)C3CCCCC3)c2C)c(=O)[nH]1 +NC(CCC(=O)Nc1ccc(OCC(O)c2ccccc2)cc1)C(=O)O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc4ncoc4cc3nc2-1 +NS(=O)(=O)OCC1OC(n2cnc3c(C#CC4CC4)ncnc32)C(O)C1O +NC(CC(=O)N1CCN(CCN2CCOCC2)C(=O)C1)Cc1cc(F)c(F)cc1F +CC(=O)Nc1cccc(CNC(=O)C2CCN(C(C)c3cccc4ccccc34)CC2)c1 +Cc1cnc(-c2cc(N3CCn4cc(C(=O)N5CCCC5)nc4C3)ncc2Cl)c(C)c1 +O=C1COc2cc3ncnc(Nc4cccc(Cl)c4)c3cc2N1CCCN1CCOCC1 +Cc1cc(OCC2(C(=O)O)CCC2)ccc1-c1ccc(-c2ncc(C(F)(F)F)[nH]2)cn1 +O=C(Nc1ccccc1Cl)OC1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 +CC(N=C(S)Nc1ccc(NC(=O)c2ccccc2F)c(C#N)c1)c1ccc(F)cc1 +COC(=O)NC(C(=O)N1CCCC1c1ncc(-c2ccc(-c3ccccc3)cc2)[nH]1)C(C)C +Cc1[nH]ncc1C(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 +N#Cc1ccc(OCC2CCC(C(=O)N3CCCC3C#N)N2)cc1 +COc1ccnc(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(N)(CC#N)CC3)n2)c1C#N +COc1ccc(-c2nc3c(N4CCN(Cc5cccnc5)CC4)c(Br)cnc3[nH]2)cc1 +CCC(C)C(NC(=O)C(CC1CCCCC1)NC(=O)c1ccno1)C(N)=O +COc1ccc(-c2ccnn2C)c(Oc2ccc(S(=O)(=O)Nc3nccs3)cc2C#N)c1 +CCOc1cc(CNC2CCCC2)cc(Cl)c1OCc1ccc(Cl)cc1 +CC(C)N1CCN(C(=O)c2ccc(CN3CCOCC3)cc2)CC1 +COc1ccc(CC(NC(=O)CCc2c[nH]cn2)C(=O)N2CC(OCCCCO)(c3ccccc3C)C2)cc1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ncc(C(C)NC(C)C)s1 +Cc1c(NC2CC2)nc(C2CC2)nc1N1CCc2ccccc2C1 +Cc1nc(C(CC2CC2)NC(=O)c2ccc(N3CC(F)(F)C3)c(-c3cccc(Cl)c3)n2)no1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCC(O)C(F)F)ncc23)ccn1 +CC(Cc1c[nH]c2c(OS(C)(=O)=O)cccc12)NCC(O)c1cccc(OS(=O)(=O)c2ccccc2)c1 +O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(Cc2ccc(F)cc2)C1 +CCCc1nc(SC(F)F)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)C(C)c2ccccc2)cc1 +Cc1cncc(-c2c(C#N)c(=O)oc3c2ccc2c3ccn2C)c1 +O=C(O)CCCCCCCOc1ccc(NC(=O)c2c(O)nc3cc(-c4cc5ccccc5s4)ccc3c2O)cc1 +O=C(Nc1ccccc1C(=O)NC(Cc1ccccc1)C(=O)O)c1cc2c(F)cccc2[nH]1 +CN1CCN(Cc2cccc3c2ccn3S(=O)(=O)c2ccc(F)cc2)CC1 +O=C(C=Cc1ccc(Br)cc1)N1CCN(Cc2ccc(F)cc2C(F)(F)F)CC1 +CCCc1nc2cc(Br)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cc1cccc(C)c1N1CC(CO)(C(=O)Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1=O +O=C(Nc1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1)c1ccccc1 +CC(C)Oc1ccccc1N1CCN(CC(=O)CC(=O)CN2CCCCC2=O)CC1 +COc1ccccc1N1CCN(C(C)CCN2C(=O)NC3c4ccccc4SC3C2=O)CC1 +[C-]#[N+]c1ccc(-c2ccc3ncc4c(c3n2)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C4)cn1 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+N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(Cc3ccc4c(c3)OCCO4)CC2)C1 +O=C(NCc1ccc(F)cc1)c1nc2n(c(=O)c1O)CCCCC2N1CCOCC1 +Nc1ccc2cccc(OCCCNc3ccc4c(c3)OC(F)(F)O4)c2n1 +CCN(C)C(=O)c1cc2c(-c3cc(NS(C)(=O)=O)ccc3Oc3ccccc3)nn(C)c(=O)c2[nH]1 +Cc1nc(-c2cccnc2)sc1C(=O)Nc1cn2nc(-c3c(-c4ccc(F)cc4)nn(C)c3C3CCOCC3)ccc2n1 +COc1ccc(C(=O)Nc2ccc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO +O=C(Cc1ccc(O)c(Cl)c1)NN=C1C(=O)Nc2ccccc21 +CCn1nc(C)cc1-c1nnc(Sc2ncc([N+](=O)[O-])s2)n1C +CN(c1ccc([N+](=O)[O-])cc1OCc1ccccc1)S(C)(=O)=O +O=C(Nc1cccc(NC(=O)c2cccc(O)c2O)c1)c1cccc(O)c1O +CC(NC(=O)c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1)c1ccccn1 +CC(C)CCn1c(=O)ccc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21 +CS(=O)(=O)Oc1ccc(CC2CN=C(N)N=C2N)cc1 +O=C(O)CCn1cc(C(=O)O)c(=O)c2cc(Cc3cccc(Cl)c3Cl)ccc21 +CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC2CCC(C(F)(F)F)CC2)cc1F +O=C(NC(c1ccccn1)C(F)(F)F)c1cc(OCC2CC2)c(C2CC2)cn1 +CNS(=O)(=O)c1cncc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)c1 +Cc1ccc(C(=O)NCc2ccccc2)cc1Nc1ncnc2c1cnn2-c1ccccc1 +Cc1cc(N(C)c2cncnc2)cc(OCc2cccc(Cl)c2)n1 +O=C(NCCc1ccc(CN2CCCC2)cc1)c1ccc(-c2ccc(F)cc2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CC=C(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C=Cc1ccccc1 +COCCNC(=O)C1CC(Sc2nc3ccccc3[nH]2)CN1Cc1ccc2ccccc2c1 +CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1cc(OC(F)(F)F)ccc1n2CCF +O=C(NCC(F)(F)F)C1CN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)C1 +CC(=O)Nc1ccc(Sc2nc(Nc3cc(C)n[nH]3)c3ccccc3n2)cc1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCc4[nH]ncc4C3)cc2F)cn1 +[C-]#[N+]C1=C(C(F)F)Nc2onc(C)c2C1c1cc2c(C)n[nH]c2cc1F +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCCCCCNC(=O)C=Cc2ccc(Cl)cc2)C1 +CCN(CC)CCOc1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(C(C)C)no2)n1 +CNC(=O)CN1CCC(Oc2cc3c(Nc4cccc(Cl)c4)ncnc3cc2OC)CC1 +Cc1ccc2sc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N4CCCCCC4)cc3)nc2c1C +COc1ccc(CNCCc2cc(OC)c(NC(=O)Nc3cnc(C#N)cn3)cc2Cl)cc1 +O=c1[nH]nc2[nH]c(CN3CCN(c4ccncc4)CC3)nc3cccc1c32 +COC(=O)C1CCN(C(=O)NC2CCc3c(-c4noc(-c5ccc(OC(C)C)c(C#N)c5)n4)cccc32)CC1 +O=C(CCc1ccc(-c2ccccc2)cc1)N1CCCC1c1ncc(-c2cccc(F)c2)[nH]1 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+OCC(O)C(O)C(O)C(O)C[S+]1CC(O)C(O)C1CO +O=c1cc(CSc2ccc(C(F)(F)F)cn2)c2ccc(O)cc2o1 +CC(CO)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2)cc(C(=O)Nc2cc[nH]n2)c1 +COc1cnc(NC2=NCC3(CN4CCC3CC4)O2)cn1 +Cc1nncn1C1CCN(Cc2cc3nc(-c4cccc(O)c4)nc(N4CCOCC4)c3s2)CC1 +CSc1nc(-c2ccc(Cl)cc2)nn1C(=O)N(C)c1ccccc1 +C=CC(=O)Nc1cccc(CNc2c(C(N)=O)cnn3cccc23)c1 +CCCCCOc1ccc2cc(-c3noc(C4CCCN4C(=N)N)n3)ccc2c1 +Cc1ccc(C(C)Nc2nc3cc(F)ccc3o2)cc1NC(=O)c1cnc2ccccn12 +N=C1NC(c2ccccc2)(c2cccc(Oc3ccccc3)c2)C(=O)N1C1CCCCC1 +CCCCCS(=O)(=O)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1 +CC(CC#CC(C)(C)O)C1CCC2C(=Cc3ccc(CO)c(CO)c3)CCCC21C +Cc1cccc2cc3cccc(C(=O)NCCCN(C)CCCNc4n[n+]([O-])c5ccccc5[n+]4[O-])c3nc12 +CCN(CCCCCC1Cc2cc(OC)c(OC)cc2C1=O)Cc1ccccc1OC +CC(C)Oc1cc(-c2ccc(CCNC(C)C(O)c3ccccc3)cc2)ccc1C(=O)O +C=CCn1cc(C2=NCC3(CN4CCC3CC4)O2)c2ccccc21 +Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1nc2cc(N3CCCC3)ncc2[nH]1 +Nc1ncc(Cc2ccc(OCCCOCCCOc3ccccc3)cc2)c(N)n1 +O=C(CCN1CCN2Cc3ccccc3CC2C1)Nc1ccccc1Cl +CC1(COc2ncc(C(F)(F)F)cn2)Cn2cc([N+](=O)[O-])nc2O1 +CCN1c2ncc(CCc3ccnc(C(=O)OC)c3)cc2C(=O)N(C)c2ccc(Cl)nc21 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OC4CCOCC4)cc3)oc2c1 +Cc1cc(Sc2cc(C#CCN3CCOCC3)nc(C#Cc3ccc(C(F)(F)F)cc3)c2)ccc1OCC(=O)O +COC(=O)CN1C(=O)c2ccccc2NC1c1ccccc1 +Cc1ccnc(CO)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)n1)c1ccccc1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCC(Oc3ccc(-n4cnnn4)cc3)CC2)cc1 +C[N+]1(C)CCC(C(=O)c2c[nH]c3ccccc23)CC1 +O=C(c1ccc(OCc2ccccc2)cc1)N(O)CCc1ccccc1 +Cc1c(C(=O)NCc2cccc(C(=O)Nc3nc4c(s3)CN(C)CC4)c2)nnn1-c1nonc1N +CCCN(C(=O)COc1ccccc1)C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1 +NCCCn1nc2c3c(c(NCCNCCO)ccc31)C(=O)c1c(O)ccc(O)c1-2 +CCCN(CCCOc1cccc(Cl)c1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 +O=C(Nc1cnc(-n2nc(-c3cccnc3)cc2C(F)(F)F)cn1)c1ccccc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NCCNC(=O)C(N)Cc1c(C)cc(O)cc1C +CN(C)C(=O)c1cc(NCc2c[nH]cn2)cc2c(Nc3ccc(F)c(Cl)c3)c(C#N)cnc12 +COc1cc(OC)c(NC(=O)C2c3ccccc3C(=O)N(CC(C)C)C2c2cccs2)cc1Cl +Cc1ccccc1NC(=O)NCCNCC(O)COc1ccc(OCCOC2CCCC2)cc1 +OC1(c2ccc(Cl)c(Cl)c2)CCN(Cc2n[nH]c3ccccc23)CC1 +CCC(CC)OC1C=C(C(=O)O)CC(NC(=N)NC(=O)c2cc(C)cc(C)c2)C1NC(C)=O +CC(C)(C)OC(=O)N1CCC(C(C(=O)NO)C(Cc2cccc(O)c2)C(=O)NC2c3ccccc3CC2O)CC1 +O=c1cc(-c2ccc(OC(F)(F)F)cc2)[nH]c2ccccc12 +CCC(NC(=O)C1CC(S(=O)(=O)c2ccccc2)CN1C(=O)C(F)(F)F)C(=O)c1nc2ccccc2o1 +C#Cc1cn(Cc2ncc(C)c(OC)c2C)c2nc(N)nc(Cl)c12 +CN1CCN(C2CC(Oc3ccc(Cl)cc3)c3c(c4ccccc4n3CC3CCNCC3F)C2=O)CC1 +COC1CC(Oc2cc(F)c(F)c(-c3ccc4c(c3)CCC(CCc3nnn[nH]3)O4)c2)C1 +Cn1c2c(c3cc(S(=O)(=O)c4cncc(F)c4)ccc31)C1CCC(C2)N1 +CCCCc1ccc(S(=O)(=O)Oc2ccc(Cn3ccnc3)cc2)cc1 +CC(C)Oc1ccc(-c2nc(-c3ccc4c(c3)cc3n4CCC3CC(=O)O)no2)cc1C#N +CS(=O)(=O)CCNC1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1 +CC1=CC(=O)C(O)C2(C)C1CC1OC(=O)C(O)C3(O)C(C)C(O)C4(O)OCC13C42 +CN(C)C(=O)NC1CCC(CCN2CCN(c3cc(Cl)ccc3Cl)CC2)CC1 +Cc1cccc(C)c1Nc1ccnc(Nc2ccc(C#N)cc2)n1 +COc1ccc(C2CC(=O)C3=C(C2)NC(C)=C(C(=O)OC(C)C)C3c2cccc(Br)c2)cc1OC +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)NCc1cccc(Cl)c1 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+Cc1ccc2c(c1)c(C#N)cn2-c1ccc(C(=O)O)cn1 +CCC1OC(c2ccc(Cl)c(Cc3cnc(-c4ccccc4)nc3)c2)C(O)C(O)C1O +Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)CCN1CCCCC21 +Clc1ccc(C2=CC3CCC(C2)N3CCOc2cccc3[nH]ccc23)cc1Cl +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(nnn2-c2ccccc2)C1 +CC(NC(=O)c1cn[nH]c1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 +CCOC(=O)C(C)(C)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +O=c1c(NCC2CCOCC2)nc2ccc(-c3ccncc3)nc2n1CC1CCCCC1 +COC(=O)c1cc(-c2ccc(S(N)(=O)=O)cc2)c(-c2ccc(F)cc2)s1 +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1Cc1cn[nH]c1 +O=C(CCCCCCC(=O)Nc1cc2c(Nc3ccc(N4CCCC4)cc3)ncnc2s1)NO +CC(=O)NCCOc1ccccc1C(=O)NCCCCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O +O=C(C=Cc1ccc2c(c1)ncn2Cc1ccccc1)NO +COc1ccccc1N1CCN(CNC(=O)c2ccc(C)cc2)CC1 +CCn1nc(C(F)(F)F)cc1C(=O)Nc1cccc(C(C)Nc2ncnc3c(C(N)=O)cccc23)c1 +CCCOc1ccc(C23c4ccccc4C(=O)N2CCN3C(=O)c2ccc(F)cc2)cc1 +COc1ccc2nc(NC(Cc3ccc(C4CC(=O)NS4(=O)=O)cc3)c3nc4ccccc4[nH]3)sc2c1 +CC(C)Cc1ccccc1C(=O)N(CCc1ccc(Cl)cc1)C1CCC2(CC1)OCCO2 +CC(C)(C)C1CCC(C(=O)N2CCc3cc(S(=O)(=O)Nc4ccc(CCCC5CCCC5)cc4F)ccc3C2)CC1 +COc1ccc(NC(=O)CC2(CC(=O)NC3C4CC5CC(C4)CC3C5)CCCC2)cc1 +O=C(CCCn1c(=S)[nH]c2ccccc2c1=O)N1CCN(Cc2cccc3ccccc23)CC1 +CN(C)CCCNC(=O)Cn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(C)c4)cc2)CC3)n1 +CC1=CSC(O)(c2ccc(C)cc2)c2noc(=O)n21 +Clc1ccc2c(NCCCn3cnc4c(N5CCSCC5)nc(Cl)nc43)ccnc2c1 +COc1ccc(OCC(=O)N2CCC3(CC2)CN(Cc2ccc(-n4nccn4)cc2)C3)cc1 +COc1ccc2c(c1OC)CN(C)CCc1cc3c(cc1C(=O)C2)OCO3 +O=C(c1ccccc1)N1CCC2(CC1)CC(C(=O)N1CCN(C3CCC3)CC1)C2 +Fc1ccc(OCc2cc(OCC3COC3)nc(-c3ccccn3)n2)c(F)c1F +COc1ccc(COc2nn3c(-c4ccccc4)nnc3c3ccccc23)cc1 +C(#Cc1nc2ncccc2nc1OCCc1ccccn1)c1ccccc1 +CC(C)=CCn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc21 +O=C1CC(O)CC(C=Cc2c(F)cc(F)cc2-c2ccc(F)cc2)O1 +O=C(NCC1CCCNC1)c1ccc(O)c2[nH]c(Cc3cccs3)nc12 +CNc1nc(Nc2cc3c(cc2OC)C(=O)N(CC(C)(C)O)C3)ncc1C(F)(F)F +CC(C(N)=O)c1ccccc1CCc1nc(Nc2cnn(C3CCNCC3)c2)ncc1Cl +Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +COc1cccc(-c2cccc(CCC3(C)CC(=O)N(C)C(N)=N3)c2)c1 +COC(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3F)ncc12 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C)CCC2 +CCC(=O)Oc1cc(C=CC(=O)c2ccc(OC)c3c2OC(C)(C)C=C3)ccc1OC +Cc1nc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC(C)N(CC4CCOCC4)CC2C)C3(C)C)c(C)o1 +COc1cccc(OC)c1-c1ccc(CC(NC(=O)C2(C)OC(C)CC2=O)C(=O)O)cc1 +O=c1c2cnc3ccc(Br)cc3c2[nH]n1-c1ccccc1 +CN1C(=O)Cn2c(=O)n(CC(=O)Nc3ccc4c(c3)CC3(C4)C(=O)NC(=O)N3C)c3cccc1c32 +CC12CCC3c4cc([N+](=O)[O-])c(O)cc4CCC3C1CCC2NS(=O)(=O)c1cccc(Br)c1 +CC#CCn1c(N2CCNCC2)nc2c1c(=O)n(Cc1ccc3ccccc3n1)c(=O)n2C +CN1C2CCC1CC(OC(=O)c1nn(CC(F)(F)F)c3ccccc13)C2 +O=C1Nc2cccnc2N(C(=O)CN2CCNCC2)c2ncccc21 +CC1CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)=CC(O)C1 +O=C(NC1CC(O)c2ccccc21)c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F +CC1(C)Oc2nc(C(F)(F)F)nc(N)c2N=C1c1ccc(C2CCC(CC(=O)O)CC2)cc1 +Nc1ncnc2c1ncn2C1OC(CO)C(OC2OC(CO)C(OP(=O)(O)O)C(OP(=O)(O)O)C2O)C1O +CCOC(=O)C=CC(CCC(N)=O)NC(=O)C(CC(=O)C(NC(=O)SCc1ccccc1)C(C)C)Cc1ccccc1 +CC1(O)CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)CC1 +c1ccc(Nc2nc3c(N4CCOCC4)ncnc3s2)cc1 +CC#Cc1cncc(-c2cccc(C3(C4CC4)NC(=N)N(C)C3=O)c2)c1 +CN1CCN=C1c1cccc(Oc2cc(C(=O)O)cc(Oc3cc(C(=N)N)ccc3O)n2)c1 +CCCCCCCCCCCCCCOc1cccc(OP(=O)([O-])Oc2cccc(C[n+]3ccsc3)c2)c1C(=O)OC +C#CCCCON=c1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)[nH]1 +O=C(COC(=O)c1ccc2c(c1[N+](=O)[O-])C(=O)c1ccccc1C2=O)NC1CC1 +COc1cc2c(cc1OC)CN(Cc1cnc(N)n3nc(-c4ccco4)nc13)CC2 +CC(C)c1cc(Oc2c(Br)cc(CC3NC(=O)NC3=O)cc2Br)ccc1O +CC(NC(=O)c1cc2c(c(C(=O)NC(Cc3ccccc3)C(O)CNC3CC3)c1)CCCO2)c1ccccc1 +COc1ccc(F)cc1Oc1ccc(C(F)(F)F)cc1C(=O)Nc1cc[nH]c(=O)c1 +CC1CCCN1C1CCC(c2ccc(NC(=O)C3CCOCC3)cc2)C1 +COc1cc(Nc2ncc(-c3ccccc3N(C)C(=O)CN3CCOCC3)o2)ccc1-c1cocn1 +CC1=CC(C)(C)Nc2ccc3c(c21)Cc1cc([N+](=O)[O-])ccc1-3 +N#CCC(=O)Nc1ccc(Cl)c(-c2nc3cc(Cl)ccc3o2)c1 +COCCOc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +COc1cc2c(cc1OC)C(c1ccc(F)cc1)N(C(=O)c1ccc(S(N)(=O)=O)cc1)CC2 +Clc1ccc(-c2ccc(-c3nc4ccccc4n3-c3ccc(N4CCNCC4)cc3)o2)cc1 +COCCNCc1c(C(N)=O)nc2n1C1CC(C1)c1cc(F)c(C#CC(C)(C)O)cc1-2 +O=C(CCCCCCCn1cc(-c2cccc(-c3ccccc3)c2)nn1)NO +COCC1CCCN1C(=O)c1cc(N)n2nc(-c3ccc(Br)o3)nc2c1 +N#Cc1ccccc1C(=O)Nc1cccc(CNc2ncnc3c(C(N)=O)cccc23)c1 +CN(Cc1ccccc1)C1C2C3CC4C2C(=O)C2C4C3C21 +CC(C)CC(NC(=O)OC(C)(C)C)C(=O)NCC#N +CCN(CC)C(=O)c1ccc2c(c1)nc(Cc1ccc(OC(F)(F)F)cc1)n2CCC(C)C +CC(C)COc1ccc(-c2n[nH]c(-c3ccncc3)n2)cn1 +Cc1ccc2[nH]c(NC3CN(C(=O)OC(C)(C)C)CC3OC(=O)c3cccc(-c4ccc(F)cc4)c3)nc2c1 +O=C(c1ccc(N2CCN(Cc3ccccc3)CC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +NCc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F +CNC(=O)c1ccc2c(c1)nc(-c1ccccc1)n2C1CCCC(NC(=O)c2ccc(Br)s2)C1 +Cn1cncc1CNc1cc2c(cc1Cl)NC(=O)Nc1cnc(C#N)c(n1)OCCCCCO2 +Cn1c(=N)n(CCOc2ccc(-c3ccccc3)cc2)c2ccccc21 +COC(=O)Nc1ccc2c(c1)NCCCC=CCC(NC(=O)C=Cc1cc(Cl)ccc1-n1cnnn1)c1nc-2c[nH]1 +N#Cc1ccc(C(=O)NC2CCC(CCN3CCC(c4coc5ccccc45)CC3)CC2)cc1 +Cc1nc(-c2ccc(Cl)s2)c(-c2ccc(S(C)(=O)=O)cc2)o1 +Cc1cc(OC(F)(F)F)ccc1NC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +C=CC(=C)CCC1(C)C(C)C(O)C(O)C23C(=CC(OC(=O)CCC)CC12)C(OC(C)=O)OC3OC(C)=O +COc1ccc(Oc2cccc(-c3c(C)cnc4c(C(F)(F)F)cccc34)c2)cc1S(C)(=O)=O +CC(=O)OCC1OC(CC(=O)C=Cc2cc(Cl)cc(Cl)c2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +c1csc(CN2CCN(c3nc4cccnc4n4cccc34)CC2)c1 +CCOC(=O)C1=CCCCC1S(=O)(=O)Nc1c(F)cccc1F +Cc1cc(-c2nc(-c3ccc(OC(F)F)c(C)c3)n3c2CCOC(CF)C3)cc(C(F)F)n1 +Cc1nc(N2CCC(NS(=O)(=O)N(C)C)CC2)nc2ccc(NC(=O)C=Cc3ccc(OC(F)(F)F)cc3)cc12 +N#CC(=CC1CC1)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cccc(F)c3F)cc2F)c2c(N)ncnc21 +CC(C)C(NC(=O)Cn1ccc2c(=O)n(C)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +Cn1c(C(F)(F)F)nc2cc(Cl)c(Oc3cccc4ccccc34)cc21 +COc1ccc(CC2NCCc3c2[nH]c2ccc(C)cc32)cc1OC +COc1ccccc1-c1ccc(CC(NC(=O)Cn2cnnn2)C(=O)O)cc1 +CCCCC1(CC)CS(=O)(=O)c2cc(CN(C)CC(=O)O)c(OC)cc2C(c2ccccc2)N1 +Cc1cc(C(CC(c2ccc(C(=O)O)cc2)c2ccccc2C)=NO)ccn1 +N=C(N)NOCCCOc1cc(Cl)cc(C(=O)N(CCc2ccccn2)CC2CC2)c1 +COc1ccc(S(=O)(=O)N2CCc3cc(OCc4ccccc4)ccc3C2C(=O)NO)cc1 +CCCn1c(=O)c2nc(-c3ccc(C(N)=O)cc3)[nH]c2n(CCC)c1=O 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+O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCCCC4COC4)cc3)cc12 +CC(C)(C)NC(=O)C1CCCCN1CC(O)C1Cc2ccc(cc2)OCCCC(=O)NC(CC(N)=O)C(=O)N1 +O=c1[nH]c(Cc2ccccc2-c2ccncc2)nc2c1cnn2C1CCOCC1 +Cn1cnc(S(=O)(=O)n2ncc3c2CN(C2COC(c4cc(F)ccc4F)C(N)C2)C3)c1 +COc1ncc(Nc2ncc(C(C)N3CCN(S(C)(=O)=O)CC3C)cc2-c2nc(C)nc3[nH]cnc23)cc1F +C[n+]1cn(-c2ccc(-c3ccc(-n4c[n+](C)c5ccccc54)cc3)cc2)c2ccccc21 +COc1ccc(Sc2ccc(F)cc2CSC(=N)N)c(CSC(=N)N)c1 +CNc1cccc(CN2C(=O)N(Cc3ccc4[nH]ncc4c3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)c1 +COC(=O)c1c(C)n(C)c2ccc3c(c12)CN1CCc2cc(OC)ccc2C1O3 +O=C(Nc1ccccc1)c1ccc(-c2cc3ccncc3cc2OC2CCNCC2)s1 +COc1ccc2c3c(c(=O)oc2c1)CN(C(=O)c1ccccc1)CC3 +CN(CCCCCCC(=O)NO)C(=O)c1ccc(N(C(=O)c2ccccc2)c2ccccc2)cc1 +O=[N+]([O-])c1ccc(S(=O)(=O)N2CCC(CCN3CCC(c4noc5cc(F)ccc45)CC3)CC2)cc1 +C(=CC1CCCN(CCCOc2ccccc2)C1)c1ccccc1 +O=C(O)c1cc(-c2cccc3cccnc23)nc2c1cnn2Cc1ccncc1 +CNCCNc1cnn(Cc2cccc(NC(=O)c3ccc(-c4ccc(OC)nc4)cc3)c2C)c(=O)c1Cl +O=C(NCc1csc2ccccc12)c1nc(-c2cccs2)nc(O)c1O +O=C1Nc2c(Cc3ccccc3O)ccnc2N(C2CC2)c2ncccc21 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+N#Cc1c(NC(=O)c2cc(S(=O)(=O)N3CCOCC3)c(Cl)cc2Cl)sc2c1CCC(c1ccccc1)C2 +O=C(NS(=O)(=O)c1cccs1)c1ccc(Cl)cc1Cl +Cn1c(=O)c2c(nc3n2CCCN3c2ccc(F)cc2)n(C)c1=O +NC(=O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O +Cc1cccnc1-c1nc(N2CCC(CS(C)(=O)=O)CC2)ncc1Cl +Cc1cc(C)c(-n2c(Cl)cn3c(CN(CCc4ccccc4)CC(F)(F)F)c(C(F)(F)F)nc23)c(C)c1 +CCCCCCCCCCC(=O)Nc1ccn(C2OC(CO)C(O)C2(F)F)c(=O)n1 +CC(C)(C)NC(=O)C(C1CC1)N1C(=O)c2cc(O)ccc2NC(=O)C1CCCCN +N#Cc1ccc(COc2ccc(Br)cc2C(=O)Nc2cccnc2)cc1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC2CCN(C(=O)N3CCC3)CC2)c2ccccc12 +Cc1ncccc1NS(=O)(=O)c1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl +CCc1ccc(CCc2ccc(CCC(N)(CO)COP(=O)(O)O)cc2)cc1 +NCCNc1nc(NCCO)nc(Nc2ccc(CCNc3nc(NCCO)nc(Nc4cccc(N)c4)n3)cc2)n1 +COC(=O)Nc1nc2cc(Oc3cc(OC)cc(OC)c3)ccc2[nH]1 +Cn1nccc1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCC(O)CC1 +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCCCCCCCCCCCCNc4c5c(nc6ccccc46)CCCC5)c3C(C1)C2 +COc1ccc2cc(CNCc3ccc(C)cc3)c(-c3ccsc3)nc2c1 +Cn1cc(CN2C3CCC2CC(Oc2cccc(C(N)=O)c2)C3)cn1 +COc1ccc2c(Oc3ccc(NC(=O)c4c(C5CCCN5)n(C)n(-c5ccccc5)c4=O)nc3)ccnc2c1 +CCN1CCN(c2nc(Nc3ccccc3)n3ncc(C#N)c3n2)CC1 +CCn1cnc2c(Nc3ccc(OC)cc3)nc(NCCN)nc21 +O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2)c2ccccc12 +Cn1cc(-c2cccc(N3CCn4c(cc5c4CCCC5)C3=O)c2CO)cc(Nc2cc3n(n2)CCOC3)c1=O +CN1CCN(C(=O)CNC2CC2c2ccc(-c3ccc(S(C)(=O)=O)cc3)cc2)CC1 +O=C(NN=Cc1c(O)ccc2ccccc12)c1ccccc1 +Cc1ccc(Cn2c(=Nc3ccc(OC(C)C)c(C)c3)[nH]c(=O)n(CCCC(=O)O)c2=O)cc1 +CCN1C(=CC=c2sc(=Cc3sc4ccccc4[n+]3CC)n(C)c2=O)Oc2ccccc21 +CCCc1cc(N)c2cc(NC(=O)C=Cc3ccc(Cl)cc3Cl)ccc2n1 +Cn1cncc1C(O)(c1ccc2nc(Cl)c(-c3ccccc3)c(Cl)c2c1)C1CC1 +COc1ncccc1CN(C(=O)CF)c1ccccc1Oc1ccccc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1ccc(Cl)nc1 +CCc1cccc(NC(=O)Nc2cc(Cl)cn(Cc3ccccc3Cl)c2=O)c1 +COc1ccc(CNC2CCC3(CC2)OC(OC)Cc2ccccc23)cc1 +Cc1ccc(S(=O)(=O)NC(CNC(=O)c2ccc3oc(-c4ccc(C(=N)N)cc4)nc3c2)C(=O)O)cc1 +CCNC(=O)Nc1ccc2ncc(-c3cnn(C)c3)nc2n1 +CN1CCN(C2=C(Cl)C(=O)N(c3ccc(Cl)c(Cl)c3)C2=O)CC1 +CCN(CC)C(=O)C1CCC2C3CN(Cc4ccccc4)C4=CC(=O)CCC4(C)C3CCC12C +Cn1ccnc1COc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl +COc1c(C)c(C)c(Cl)c(N)c1CC=C(C)CCC(=O)O +CC1CCC(Oc2cc(C#N)ccn2)CN1C(=O)c1cccc(F)c1-n1nccn1 +COc1cc(OC(C)C)c2cc(-c3cn4nc(Br)sc4n3)oc2c1 +NC(=O)c1cc(N(CCOS(N)(=O)=O)CCOS(N)(=O)=O)c([N+](=O)[O-])cc1[N+](=O)[O-] +COc1ccc(-c2nn3c(N)nc4ccccc4n3c2=O)cc1 +O=P(O)(O)C(F)(F)c1ccc(CC(Cc2ccc(-c3ccccc3)cc2)(c2ccccc2)n2nnc3ccccc32)cc1 +CC(C)N1CCN(C(CN2CCN(CCCc3ccccc3-c3ccc(-c4ccccc4)cc3)CC2)c2ccc(F)cc2)CC1 +CN(C)CCOc1ccc(C(=C(CCCl)c2ccccc2)c2ccccc2)cc1 +CCC(C)C(NC(=O)C(S)C(C)C)C(=O)N1C(C(=O)O)CC2CCCCC21 +O=C(NCc1cn(-c2ccccc2F)c2cc(F)ccc2c1=O)c1ccc(Cl)nc1 +CCCCNc1cccn2c(-c3ccnc(NC4CCCC4)n3)c(-c3ccc(F)cc3)nc12 +O=C1Nc2ccc3ncsc3c2C1=CNc1ccc(S(=O)(=O)N[n+]2ccc3ccccc3c2)cc1 +COc1ccc(CC2CC(C)(C)N(C)C(C)(C)C2)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1 +COc1ccc2[nH]cc(CCNC(=O)CCc3cc[n+](Cc4ccccc4F)cc3)c2c1 +COc1ccc2cc(C(C)(O)CCN3CCCCC3)ccc2c1 +CC(C)(C)C(=O)Oc1coc(CSc2nc3ccccc3o2)cc1=O +CCc1nc2c(-c3ccc(OC)nc3C)ccnc2n1C(CC)C1CC1 +CCN(CC)C(=O)c1ccc(C(c2cccc(OC)c2)N2CC(C)N(Cc3ccccc3)CC2C)cc1 +CC(NC(=O)c1cc(-c2cnn(C)c2)cnc1N)c1c(Cl)ccc(F)c1Cl +COc1cc(C(=O)NC2CC2c2ccccc2)ccc1-c1cn[nH]c1 +CN(Cc1ccccc1)C(=O)CN(C#N)NC(=O)OC(C)(C)C +Cc1nn(Cc2ccc(Cl)cc2)c(C)c1NC(=O)c1ccc([N+](=O)[O-])cc1 +O=c1c2cnc3ccccc3c2ncn1CCCCN1CCN(c2cccc(Cl)c2)CC1 +CN(C)c1ccc(C=CC=C2C(=O)N(C)c3ccccc32)cc1 +COc1cccc(N(C)C(=O)c2ccc(-c3cccc(C)c3)s2)c1 +COc1ccc(-c2c(-c3nc(C)c4c(=O)[nH]c(C)nn34)c(C)nn2C)cn1 +CS(=O)(=O)c1ccc(-c2cnc3ccc(-c4ccc(C(F)(F)F)nc4)nn23)cc1 +CCNC(=O)C1OC(n2cnc3c(N)nc(C#Cc4ccc(C(F)(F)F)cc4)nc32)C(O)C1O +FC(F)(F)Oc1cccc(-n2nnc3ccc(NCCc4cccnc4)nc32)c1 +CCCC[S+]([O-])c1sc2nc(-c3nccs3)cc(-c3ccc(COC(=O)NCC)cc3)c2c1N +O=C(CCCSCC(NC(=O)c1ccc(Br)cc1)C(=O)NCc1ccccc1)NO +CC(C)c1c(C(=O)N(C)Cc2ccccc2F)nn(-c2ccc(F)cc2)c1CCC(O)CC(O)CC(=O)O +Cc1ccc(Oc2ccc(N(CCC(=O)NO)S(C)(=O)=O)cc2)cc1 +O=C(CC(CCCc1ccccc1)C(=O)NC(CC1CCCCC1)C(=O)NCCc1ccc(S(=O)(=O)O)cc1)NO +Cc1nc(C(=O)NCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c(C)n1-c1ccccc1C(F)(F)F 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+CS(=O)(=O)Nc1ccc2ccc3ncc(-c4ccccc4)cc3c(=O)c2c1 +CCC(C)Sc1ccc(-c2nc3ccc(C)cn3c2NC2CCCCC2)cc1 +NC1=NC(c2ccco2)NC(NCCCOc2ccc(Cl)cc2)=N1 +CC(CN)c1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4sccc4c23)cc1 +C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(C=NOCCO)c(F)c2F)c(F)c1 +CC(C)C(=O)OCC(C)(C)CC1=C(O)C(=O)c2ccccc2C1=O +CN(C)C(=O)CN(C)C(=O)C1CCc2c(sc3ncnc(Nc4ccc5[nH]c(=O)sc5c4)c23)C1 +CC(=O)C1CCC2C3CCC4N(C)C(=O)CCC4(C)C3CCC12C +Cc1cc(-c2ccccc2)cc(C)[n+]1CC(=O)Nc1ccc(S(N)(=O)=O)cc1I +COc1cccc(OC)c1C(=O)Nc1c[nH]nc1C(=O)NC1CC2CCC1C2 +CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3ccccc3)c(Oc3ccc(Cl)cc3)s2)cc1 +CC1COCCN1c1nc(N2CCOCC2)nc2[nH]c(-c3cnc4cc[nH]c4c3)nc12 +CN(CCCNc1nc2ccc(Cl)cc2n2cccc12)CCCNc1nc2ccc(Cl)cc2n2cccc12 +N#Cc1ccc(C(=O)Nc2cc(-c3ccccc3)nn2-c2ccccc2)cc1 +O=S(=O)(c1cccc(C(F)(F)F)c1)c1sc2ncccc2c1-c1ccc(Cl)cc1 +CCCC#Cc1ccc(C(CO)NC(=O)C2CC2c2cccs2)c(OC)c1 +NC(C=C(CCCCCCNC(=O)c1ccccc1)CP(=O)(O)O)C(=O)O +COc1ccccc1N1CCN(CCCN2CC(=O)N3CCCCC3C2=O)CC1 +CCc1nccc(-c2ccc(C3CC3)nc2)c1C#Cc1ccc(N)nc1 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+Cc1cn(CC=CCN2c3cccc4c3N(CCC4)S2(=O)=O)c(=O)[nH]c1=O +Cc1ccnc(Nc2ccc(Oc3ncccc3-c3ccccc3)cc2)c1 +O=C(CCCCN1C(=O)CN=C(c2ccccc2)c2ccccc21)NO +COc1nc(Br)cnc1NS(=O)(=O)c1cccc(C(N)=O)c1-c1ccccc1 +COc1cccc(CC2(C(=O)NC(Cc3ccc(NC(=O)c4c(Cl)cccc4Cl)cc3)C(=O)O)CCCC2)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc2ccccc2c1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NCc1cnoc1 +CCc1ccc2cc(OC)ccc2c1C(=O)c1cc(OC)c(OC)c(OC)c1 +CCCc1c(OCC(O)COc2ccc3c(O)c([N+](=O)[O-])c(=O)oc3c2CCC)ccc(C(C)=O)c1O +CCCN(CCCCc1c[nH]c2ccc(F)cc12)C1COc2c(ccc3ncccc23)C1 +O=C(O)CCC=C(c1ccc(-c2nc(C(=O)NCCCCC3CCCCC3)co2)cc1)c1cccnc1 +CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4ccccn4)ccc3Sc3ccc(N)cc3)ncnc2n1 +COc1ccc2c(c1)C(CC(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NCc1c(F)cccc1F)CC2=O +FC(F)(F)c1cc(COCC2(c3ccccc3)CCC(N3CCCCC3)CC2)cc(C(F)(F)F)c1 +Cc1ncc(Cl)cc1C(=O)NC1CCC(Cn2nc(C)c(C)c2C)CC1 +C=CC(C)(C)c1cc(-c2ccc(N3CCOCC3)nc2)nc2ncnc(N)c12 +CCCc1c(C(=O)OCC)cn2ncnc(Nc3ccc4c(cnn4Cc4ccccc4)c3)c12 +CC(C)c1ccc2c(c1)CCCN2C(=O)c1ccc(O)cc1O 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+O=C(Nc1ccc2c(c1)OCO2)c1ccccc1Cn1ccc2ncnc-2c1 +CC1CCC(C(O)c2ccc(Cl)c(Cl)c2)N1C(=O)Nc1ccc(CNC(=O)C(C)(C)C)cc1 +N#Cc1ccc(S(=O)(=O)C2CCN(CCc3ccc(F)cc3F)CC2)cc1 +COCC1CCCN1C(=O)c1cn2c(-c3ccc(Cl)cc3Cl)c(CN)c(C)nc2n1 +CC1CCCCC1N(C(=O)c1cc(C2CC2)on1)C1CCCCCC1 +CCOc1ccc(C=CC(=O)N2CCN(S(=O)(=O)c3ccc(Br)cc3)CC2)cc1 +O=C(Nc1ccccc1)NC1C2CCN(CC2)C1Cc1cccnc1 +N#Cc1cc2cc(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)c(O)cc2n1Cc1cn[nH]c1 +CC(C)Oc1cc2c(-c3cc(N4CCOC(C)C4)ncn3)n[nH]c2cc1F +O=C1C(=O)N(Cc2cccc(I)c2)c2ccc(S(=O)(=O)N3CCCC3CF)cc21 +FC(F)(F)Oc1cccc(-n2nnc3ccc(N4CCC5(CCNCC5)C4)nc32)c1 +COc1ccccc1N1CCN(CCCCCNC(=O)c2nnn(Cc3ccccc3)c2C)CC1 +COc1ccc2c(c1)C(C)=CC(C)(C)N2S(=O)(=O)c1ccc(NC(C)=O)cc1 +COc1cc(NC(=O)Cc2cccc(C(F)(F)F)c2)ccc1C=NNC(=O)c1ccc(O)c(C#N)c1 +Cc1nc(O)c2cc(CN(C)c3ccc4c(c3)CN(C(CCC(=O)O)C(=O)O)C4=O)ccc2n1 +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCOCC1 +Cc1ccc(NC(=O)CN2C(=O)NC(=Cc3cccn3-c3ccc(C(=O)O)cc3)C2=O)cc1 +COc1ccc(S(=O)(=O)n2c(C)c(C(=O)N3CCCNCC3)c3cc(C)ccc32)c(C)c1C +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=S)Nc1cccnn1)CC2 +NC(=O)c1cccc2[nH]c(-c3ccc(-c4noc(=O)[nH]4)cc3)nc12 +COc1ccc2c(c1)OCCC=CCN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3cccc(Cl)c3)ccc2n1 +Cn1cc(C2=C(c3cn(CCCn4ccnc4)c4ccccc34)C(=O)NC2=O)c2ncccc21 +Cc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCCO2)[nH]1 +COc1cccc2c1-c1ccc(NS(C)(=O)=O)cc1C(c1cc(C)cc(C)c1)O2 +Cc1ccc(-c2cc(NCCCn3ccnc3)c3ccccc3n2)cc1 +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccccc4C(F)(F)F)O2)C3=O)cn1 +Cc1cn2c(n1)CN(C(=O)c1cccc(C(F)(F)F)c1Cl)CC2 +Cc1cc(NC(=O)Nc2cc(C3CC3(F)F)nn2-c2ccccc2)ccc1F +CCOc1ncc2c(n1)c(NC1CC1)nc1cc(C(=O)O)ccc12 +O=C(Nc1n[nH]c2ccc(Cc3cc(F)cc(F)c3)cc12)c1ccc(CN2CCCCC2)cc1NC1CCOCC1 +NCC1CCC2CN(c3cc(N)n4nc(-c5ccco5)nc4n3)CCN2C1 +CC(C)(C)c1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1 +CCCCCCN(CCCCCC)C(=O)C1CCCc2c1c1ccccc1n2CCF +CCC(C)CCC=C(C)CC(C)CCC=CC(O)C1(C)CCC(=O)O1 +COc1cc(OC)c(F)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3ncccc23)c1F +COc1ccc(NC(=O)c2ccc(C(F)(F)F)c(Nc3ncnc4cnc(N(C)C)nc34)c2)cc1C(F)(F)F +COc1cccc(C(=O)Cn2cnc3c(C#N)c(N4CCNCC4)n(Cc4ccccc4)c3c2=O)c1 +Cc1ccc2[nH]c3c(c2c1)CCOC31CCC(c2ccccc2)(N(C)C)CC1 +O=C(Nc1ccc(O)cc1)C(=O)c1c[nH]c2ccccc12 +CC(C)(O)c1ccccc1CCC(SCC1(CC(=O)O)CC1)c1cccc(C=Cc2ccc3sc(Cl)cc3n2)c1 +Cc1c(C)c2c(c(C)c1Nc1ccc3c(c1)CC(C)(C)O3)CC(C)(C)O2 +CCCOc1ccc2c3cc[n+]4nc(CC)c(CC)cc4c3n(C(=O)OC(C)(C)C)c2c1 +CC(C)c1cccc(C(C)C)c1NC(=O)CC(CC(c1ccccc1)c1ccccc1)=NO +CC(=O)NCc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2N)cc1 +Cc1ccc([P+](Cc2ccc(C(=O)c3ccccc3)cc2)(c2ccc(C)cc2)c2ccc(C)cc2)cc1 +CNC(=O)Nc1nc2cc(Oc3cc(OC)cc(OC)c3)ccc2[nH]1 +Cc1cc2nc(NC(=O)N3CCN(c4ncc(C(O)C(C)O)cc4F)CC3)sc2cc1C +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3cccc(C#N)c3)CC2)nc2ccsc12 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)CCN1C(=O)CNCC21 +Cc1ccc(C(=O)NC(=O)Nc2ccc3c(c2)NC(=O)C3=Cc2ccc[nH]2)cc1 +O=C1Nc2ccccc2C1=Cc1cc[n+](Cc2c(F)cccc2Cl)cc1 +O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCC(Cc2cccc(Oc3ccccc3)c2)CC1 +CC(Cc1ccccc1)Nc1cc(Cl)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1ccc(F)cc1Nc1cc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +CCC=Cc1cccc(C(=O)c2c(CC)c(C)nc(O)c2N(C)C)c1 +O=C(CC1CCC2(CC1)OOC1(O2)C2CC3CC(C2)CC1C3)N1CCNCC1 +COc1ccc(CC(=O)N2CCC(Oc3ccc(C(F)(F)F)cn3)CC2)c(B(O)O)c1 +C=C1CCC(O)CC1=CC=C1CCCC2(C)C1CCC2C(C)CC[S+](=N)([O-])c1ccccc1 +CCN(CC)CC(=O)Nc1ccc2nc3n(c(=O)c2c1)CCc1c-3[nH]c2ccccc12 +CCCCCCOc1ccc(NC(=O)ON=Cc2ccc(F)cc2)cc1 +CC(Nc1nc(Nc2ccc(S(=N)(=O)C3CCCC3)cc2)ncc1Br)C(C)(C)O +COc1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1OC +CC(C)CC(CNC(=O)Nc1ccc(Cl)cc1)N1CCN(C2CCCCC2)CC1 +CC(=O)OC1C(c2ccc(=O)oc2)C2(C)CCC3C(CCC4CC(O)CC(O)C43C)C23OC13 +N#CCC(=O)N1CC(F)(F)C12CCN(c1ncnc3[nH]ccc13)C2 +Cc1ccc(S(=O)(=O)c2ccc3oc4c(c3c2)CNCC4)cc1 +COc1cc(C(=O)N2CCC2c2noc(-c3cccc(Cl)c3OC)n2)c(-n2nccn2)cc1C +CCOC(=O)C1C(OC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC2CCC1N2C +OC1(c2ccc3c(c2)OCO3)CCC(N2CCN(Cc3ccccc3Cl)CC2)CC1 +O=C(Nc1cccc(SC(F)(F)F)c1)Nc1cccc2cnccc12 +CCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)C(O)C(C)C)S(=O)(=O)c1ccc(OC)cc1 +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2nc(CN3CCN(CCN4CCOCC4)CC3)ccc2c1 +COc1ccc(-c2c(C(=O)NS(C)(=O)=O)n(Cc3cccc(C(F)(F)F)c3)c3ccccc23)cc1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4ccnnc4)s3)c2)C(O)C(O)C1O +Cc1ccc2nc(Cl)c(C=CC(=O)c3ccc(C)s3)cc2c1 +C=CC(=O)NC1=CC=C2N=CN=C(Nc3ccc(OCc4ccccc4)cc3)C21 +COC1CN(c2nc(-c3nccs3)c(C(=O)O)s2)CCC1NC(=O)c1[nH]c(C)c(Cl)c1Cl +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cscn1 +CC#Cc1cc2cc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)ccc2cn1 +COc1c(C)c(O)c(C=O)c2c1C(O)CC(c1ccccc1)O2 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)NC1CCC(Oc2ccc(C(F)(F)F)cn2)CC1 +CCOCc1noc(N)c1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CCNC(=O)c1cnc(N)c2cc(-c3ccc(N4CCOCC4)cc3)sc12 +N#Cc1cnc(-n2cc(C(=O)Nc3ccc(C4CNCCO4)c(F)c3)cn2)cn1 +NC(=O)c1cccc(-c2ccc3c(c2)nn2cc(-c4ccccc4)c(-c4ccc(C5(N)CCC5)cc4)nc32)c1 +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccccc2)nc2cc(Cl)ccn12 +O=C(c1ccc(OCC(F)(F)F)nc1)N1CCC(O)(c2ccccc2)C2CCCCC21 +CC1NCc2cncn2Cc2ccc(C#N)c(c2)Oc2ccc3cccc(c3c2)NC1=O +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccccc4F)ncc23)ccn1 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+COc1ccc(NC(=O)Nc2nn(-c3ccccc3)c(=O)c3ccccc23)cc1 +O=C(C(c1ccc(Cl)cc1)c1cncnc1)N1CCN(c2ccc(C(F)(F)F)cc2)CC1 +Cc1nc(NC(C)c2cccc(OCc3nc(C(=O)O)co3)c2)cc(-c2ccc3ncsc3c2)n1 +CC1(O)CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)C1 +Cc1cccc(-c2c(-c3cccc(OC(F)(F)F)c3)cc3n2C(CCNC(=N)N)CNC3=O)c1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1Nc1cnn(CC(F)(F)F)c1 +CC(C)CC(NC(=O)C(O)C(N)Cc1ccccc1)C(=O)N1CCCC1C(=O)N1CCCC1C(=O)O +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(Cn2cc(F)cn2)CN1 +O=C(O)c1ccc(COc2ccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)cc2)cc1 +Cn1cc(Nc2ncc(Cl)c(NC3CC4CNCC4C3)n2)cn1 +O=C(O)c1ccc(N2CC3(CCN(Cc4nc(-c5ccccc5)oc4-c4cc(F)c(F)cc4F)CC3)OC2=O)cc1 +Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(c1)OCc1ccc(OCC3COC(C)(C)O3)cc1C2=O +CC(C)(CC(=O)N1CCOCC1)NCC(=O)N1CC(F)CC1C#N +Fc1cc(-c2ccccn2)cn2c(C(F)(F)c3ccc4ncccc4c3)nnc12 +CN1CC(C)(COc2ccc(C(=N)N)cc2)Oc2cc(N(CC(=O)O)Cc3ccc(F)c(F)c3)ccc21 +CC(C)N1CCCN2C(=O)c3c(O)c(=O)c(C(=O)NCc4ccc(F)cc4)cn3CC21 +CCOc1ccccc1-c1ccc(-c2nc3ccc(F)cc3c(NCC(=O)O)c2C#N)cc1 +Cc1cc(-c2cc(C(=O)NC3C4(C)CCC(C4)C3(C)C)nn2-c2ccccc2)ccc1Cl +CC1CCC(Oc2ccc3ccccc3n2)CN1C(=O)c1ccccc1-n1nccn1 +CC1CN(Cc2ccc(Cl)cc2Cl)C(=O)C(=O)N1c1ccccc1 +CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(C(=O)Nc2ccccc2)c(F)c1 +CN(CC(=O)NC(CCCSC(=N)N)B(O)O)C(=O)CCc1ccccc1 +O=C(CCCc1ccccc1)Nc1nc2ccccc2c(=O)s1 +CCCCc1nc(SCSC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 +O=C1NC(=O)C(Cc2ccc(Oc3ccc(F)cc3)cc2)S1 +NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)CCO)c(F)c1F +CC(C)(C)c1ccc(-c2cccc(NC(=O)Nc3ccc(Cl)cc3)c2)cc1 +OC(O)(CCCCCNc1c2c(nc3ccccc13)CCCCC2)C(F)(F)F +CC(C)CC(NC(=O)C1(c2ccccc2)CC1CN1CCC2(C)c3cc(O)ccc3CC1C2C)C(=O)NCCCCN +CC(=O)Nc1nc(C(CCN2CCC(c3ccccc3)CC2)C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cs1 +c1ccc2c(CCN3CCCC(c4ccnc(NC5CC5)n4)C3)csc2c1 +CCNC(=O)c1ccc(-n2cnc3cc(Cl)ccc32)s1 +CC(=O)c1cn(C)c2ccc(Nc3nccc(-n4cc(CN5CC(O)CO5)c(C)n4)n3)cc12 +CCC(=O)CCC(=O)NC(Cc1ccccc1)C(O)CN(CC(C)CC)S(=O)(=O)c1ccc(OC)cc1 +O=C(NCC(c1cnc(C(F)(F)F)nc1)N1CCOCC1)c1ccc(Cl)cc1Cl +COc1ccc(C2=C(c3ccc(F)cc3)C(=O)OC2)cc1 +O=C1NC(=Nc2nc3ccccc3s2)SC1=Cc1ccccc1Cl +CCCn1c(=O)[nH]c2nc(-c3cnn(CC#Cc4cccc(C(F)(F)F)c4)c3)[nH]c2c1=O +Clc1ccc(N2CCN(CCCCc3nc4ccccc4o3)CC2)cc1 +COc1cc2[nH]c(=O)n(C)c(=O)c2cc1-c1cnco1 +COc1c(C)cc(S(=O)(=O)N2CCCC(Cn3ccnc3)C2)cc1C +O=S(=O)(Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1)c1ccc(I)cc1 +O=C(O)c1ccc(S(=O)(=O)N(CCCC(F)(F)F)c2sc3ccccc3c2Cl)cc1 +c1c2c(cc3c1SSc1cc4c(cc1SS3)OCCO4)OCCO2 +CC(C)n1cc(C2=NCC(=O)N3CCc4c(cccc4-n4cccn4)C3=C2)cn1 +Cn1cccc1-c1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3F)c2s1 +COc1ccc(CCc2cnc3nc(N)nc(N)c3c2)cc1OC +Cc1cc(C)c(S(=O)(=O)N2CCC(C(=O)NC3CCCC3)CC2)c(C)c1 +COc1ccccc1-c1cccn2nc(Nc3cccc(N4CCN(C)CC4)c3)nc12 +Cc1ccc(C(C)(C)NC(=O)COc2cc(C)c3c(C4CC4)nn(C)c3n2)cc1 +Cc1cc(C(Nc2ccc(Cl)c(CNCCC(=O)O)c2)C(F)(F)F)ccc1Cl +Cc1ncccc1C(C#N)N1CCN(C(=O)CC(NCc2ccccc2)c2ccccc2)CC1 +Oc1nc(NCCCNC2CCNc3c(Br)cc(Br)cc32)nc2ccsc12 +CN(C)CCNC(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C +COc1ccc(Br)c(CC2CCN(CCc3ccc4ccccc4c3)CC2)c1 +OCc1ccc(C#Cc2cncnc2Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)o1 +Cc1cc(CCN2CCOCC2)ccc1Nc1nccc(-c2c[nH]c3ncccc23)n1 +CC(C)c1nc(C(=O)NC2CCN(CCF)CC2)c2ccccn12 +Clc1ccc(Cl)c(-c2cc(Cl)cc3c2N2CCNCCC2C3)c1 +O=C(Nc1ccccc1)c1cccc(-c2cnc(-c3c[nH]c4ccccc34)[nH]2)c1 +c1ccc(C2=NN(c3ccccc3)C(c3ccc4ccccc4c3)C2)cc1 +CC1OC(=O)C2(NCc3cscn3)CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4C#N)cn3)C12 +CC1=CC(C)(C)N(Cc2ccccc2)c2ccc(OC(=O)C3CCCCC3)cc21 +O=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1nc2ccccc2[nH]1 +O=S(=O)(Nc1cccc2cccnc12)c1ccc(Cl)cc1F +O=C1CC(O)CC(CSc2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)O1 +O=C(c1ccco1)N(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Cc1cnccc1-c1ccccc1 +C#Cc1ccc2c(c1)N(CCCN(C)C)c1ccccc1CC2 +CC(=O)CCCCC(=O)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1C(=O)NCc1cccnc1 +COc1ccc(O)c(CNc2ccc(S(N)(=O)=O)cc2)c1 +Oc1c(-c2ccncc2)c(-c2ccc(F)cc2)nn1-c1ccc(Cl)cc1 +O=C(O)CCc1c(C(=O)O)[nH]c2cc(Cl)ccc12 +O=C(NCCC1CN=C(c2ccccc2)c2ccccc2N1)c1ccc(F)cc1 +Fc1cccc2c1[nH]c1c3c4ccccc4nc-3c[nH]c12 +O=C(O)COc1cccc2c1CCC(COC(=O)N(c1ccccc1)c1ccccc1)C2O +C=C(C)C1CCC2(NC(=O)NC(C)(C)CO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +COc1cc(C=CC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OC +CC(NS(=O)(=O)C(C)C)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1 +Cc1ccc(-c2ccn[nH]c2=O)cc1NC(=O)C1=CN(C)C(=O)CC1c1ccc(F)cc1 +Cc1c(C(O)CN2CCC3(CCCN(C(=O)c4ccc(-n5cnnn5)nc4)C3)C2)ccc2c1COC2=O +CCNC(=O)c1ccc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4ccc(OC)cc4F)cc32)cc1C +O=C1SC(=Cc2cccc(OCc3ccc(B(O)O)cc3)c2)C(=O)N1Cc1ccc(F)cc1 +COC1CCC(Nc2cc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 +CCn1c(CNc2ccc(Cl)cc2)nnc1SCC(=O)Nc1cccc(C)c1C +O=C(Nc1nc(-c2ccccc2)nc2nn(CCc3ccccc3)cc12)c1cccc(Cl)c1 +COc1ccccc1N1CCN(CCCn2nc(-n3cnc4ccccc43)ccc2=O)CC1 +CCC1OCC(=O)C1NC(=O)C(CC1(C)CCCC1)NC(=O)c1ccc(NS(=O)(=O)c2cccc(F)c2)cc1 +Cc1cccc(C)c1N1CC(C(=O)Nc2cc(N3CCCC3)cc(C(F)(F)F)c2)CC1=O +Cc1nn(-c2cccc(N)c2)c2oc3ccccc3c(=O)c12 +CCCCn1nc(C(C)C)c(C(=O)O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCCC)C(C)C)ccc1OC +COc1ccccc1N1CCN(CCCCCC(=O)n2c3ccccc3c3ccccc32)CC1 +O=S(=O)(Nc1cncc(Br)c1)c1ccccc1C(F)(F)F +C=CCOCC(O)CN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 +C[N+]1(C)CCC2(CC1)OC(=O)C(c1ccccc1)(c1ccccc1)O2 +CN1CCN2CC(c3ccc(N)cc3)c3ccccc3C2C1 +N#Cc1ccc2[nH]c(-c3ccc4[nH]c(-c5ccc6ccccc6c5)nc4c3)nc2c1 +COc1nccc2oc(-c3cnc4ccc(OCC5CNCCO5)nn34)cc12 +O=C(O)CC1CCc2cc(OCCCOc3ccc(-c4nc5c(s4)CCCC5)cc3)ccc21 +CCS(=O)(=O)Nc1cccc2c1CCC1C2c2cc(O)c(Cl)cc2CCN1C +COc1ccc(S(=O)(=O)N(Cc2cccnc2)c2c(C(=O)NO)cnc3c(OC)cccc23)cc1 +N#Cc1cccc(Cc2ccc(C(=O)NCc3c[nH]c4ccc(Cl)cc34)cc2)c1 +CN(Cc1cc(-c2ccccc2)ccc1O)CC(O)c1ccccc1 +CCc1c(C(=O)c2cc(C)cc(C)c2)n(COCc2ccc(F)cc2)c(=O)n(O)c1=O +COc1cc(C(C)=O)ccc1OCCCN1CCC(c2noc3ccccc23)CC1 +CCC(C)C1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)N(C)C)c1ccc(C)[n+]([O-])c1 +CCCn1cc(C(=O)c2cccc3cccc(Cl)c23)c2ccccc21 +CC(C)(F)CCNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1NC(C)(C)C +O=C(c1cccc2[nH]ccc12)N1CCC(F)(F)C(Oc2ccc3ccccc3n2)C1 +Nc1[nH]nc2ccc(CN3C(=O)N(Cc4ccccc4)C(Cc4ccccc4)C(O)C3CCc3ccccc3)cc12 +Cc1cc(C2(O)C(=O)Nc3ccc(-c4c(C)noc4C)cc32)ccc1F +CCCC(=O)Nc1n[nH]c2cc(Cl)c(-c3ccc(F)cc3)cc12 +CCC(NC(=O)c1c(O)c(-c2ccccc2)nc2cc(OC)ccc12)c1ccccc1 +CC1(C)CC(C)(C)c2cc(CN3CCC4(CC3)CN(c3ccc(C(=O)O)cc3)C(=O)O4)ccc2O1 +CCOCn1nnc(-c2ccc(F)cc2)c1-c1ccnc(NC(C)c2ccccc2)n1 +CCCCCCCCC=CCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2cc(OC)c3ccccc3n2)cc1 +CN(C)C1(c2ccccc2)CCC(c2ccccc2)(N(C)Cc2cccc(F)c2)CC1 +CC(C)S(=O)(=O)N1CCC(c2c[nH]c3c(C(N)=O)cc(-c4ccccc4)cc23)CC1 +CNc1cc(N(C)Cc2ccc(F)cc2)nn2c(C)nnc12 +C=C(CC)C(=O)c1ccc(OCC(=O)NCCc2ccc(OP(=O)(OC)OC)cc2)c(Cl)c1Cl +COCCc1ccc(-c2c(C)nc3c(N4CCOCC4)nccn23)nc1 +CN(C(=O)CNc1ccccc1C#N)C(CN1CCC(O)C1)c1ccccc1 +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(C4(C#N)CC4)cc3)nnc2c1 +COc1c(O)c(OC)c2c(=O)cc(-c3ccc(O)cc3)oc2c1OC +COCCN(C)C(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +CNC(Cn1c(=O)c(-c2cccc(OC)c2F)c(C)n(Cc2c(F)cccc2F)c1=O)c1ccccc1 +CC(NC(=O)C(C)(C)C#N)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CCOc1ccc(Cc2cc(C3CCN(CC4CN(C(C(=O)O)C(C)CC)CC4c4cccc(F)c4)CC3)n(CC)n2)cc1F +CCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccccc3)C2)C1c1ccccc1Cl +Cc1cc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)ccc1Cl +CC(C)C#CC(c1ccc(Cl)cc1)N1CCC(CC(=O)O)CC1c1ccc(C(F)(F)F)cc1 +COc1cc(C(=O)n2nc(Nc3ccc4c(c3)OCO4)nc2N)cc(OC)c1OC +CN(C)S(=O)(=O)CC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1 +COc1ccccc1C(CC(=O)O)NC(=O)c1cc(=O)n(-c2ccccc2F)[nH]1 +c1ccc(-c2cncc(N3CC4CC(C3)N4)c2)cc1 +COC(=O)C=Cc1ccc2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)n2c1 +CCCCSC=C1C(=O)OC(COC)C2(C)C1=C(O)C(=O)C1=C2C(OC(C)=O)CC2(C)C(=O)CCC12 +CCn1c2ccccc2c2cc(S(=O)(=O)Nc3ccc(OC)c(Cl)c3)ccc21 +Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)NCCc1cnc[nH]1)c1nnc(C)n1-2 +O=c1[nH]nc2c3c([nH]c4cc(F)cc1c43)CCC2 +CC(C)CC(CC(=O)NO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCc1ccccn1 +COCCN1CCC(Cn2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)CC1 +CC1(C)CC(NC(=O)Nc2cccc3[nH]ncc23)c2ccc(F)cc2O1 +NC(Cn1c(=O)c(-c2ccccc2F)c2n(c1=O)C(c1ccccc1)CO2)c1ccccc1 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+CN(C(=O)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cnc(N2CCCC2CO)cc1-c1ccccc1Cl +COc1cccc(-c2cn3cc(OCCCN4CCCCC4)cc3c(=O)n2CC(=O)NC2CC2)c1 +Cc1ccc(NC(=O)N2CC(CC#N)(n3cc(C(N)=O)c(Nc4ccccc4)n3)C2)cc1F +CCCCc1nc(CCC)c(CCC(=O)OCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 +O=C(NC1CCCCN(Cc2c(F)cccc2F)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +O=C(Nc1cc(Cl)cc(Cl)c1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1 +CC(C)N1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cn(C)cn5)n4)cc(Cl)c3[nH]2)CC1 +Nc1nc2[nH]c(SCc3ccc(Br)cc3)nc2c(=O)[nH]1 +COc1cc2c(c(OC)c1)C1C3CCCC(C(=O)N1CC2)N3C(=O)C(=O)c1ccc(Cl)cc1 +O=C(O)CCC1(O)OC2=CC(=O)c3c(O)cc(O)cc3C2=C1c1ccc(O)cc1 +CN(CC12CCC3(O1)C1Cc4ccc(O)cc4C3(CCN1CC1CC1)C2)C(=O)c1ccccc1 +CCCCN(CCCC)C(=O)C1OC(C(=O)O)=CC(N=C(N)N)C1NC(C)=O +CC(=O)N1CCCC1C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1 +CCCCCCCCc1nc(-c2cc(S(=O)(=O)N3CCN(C)CC3)ccc2OCC)[nH]c(=O)c1Br +Cc1c(NS(=O)(=O)c2ccc(-c3cccc(CNC(C)C)c3)cc2)c(CC(C)C)nn1C +NS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)CC3(CCC3)C2)cc1 +Cc1ccc(-c2cc(C(=O)NCc3ncc[nH]3)nc(N)n2)o1 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+COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CCN(C(=O)CCCc1ccccc1)C2 +CNCC(Nc1ncnc2c(C(N)=O)cccc12)c1ccccc1 +Fc1ccc(C(CCCN2CCN(C(c3ccccc3)c3ccccc3)CC2)c2ccc(F)cc2)cc1 +O=C(NC1c2ccccc2CC1O)C(Cc1ccccc1)CC(O)CN1C(Cc2ccccc2)CC(Cc2ccccc2)S1(=O)=O +CS(=O)(=O)N1CCC2(CC1)OOC1(CCCCCCCCCCC1)OO2 +COc1cccc(-c2cc(N3CC(N)C(c4cc(F)c(F)cc4F)C3)ncn2)c1 +CC(C)(C)C(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +CCCN(c1nc(-c2ccc(Cl)cc2Cl)n(CC)n1)C(C1CC1)C1CC1 +NC(=O)c1cc(-c2cccc(N)c2)cc2cccnc12 +CCc1ccc(CCNCCCSCCNCC(O)c2ccc(O)c3[nH]c(=O)sc23)cc1 +Cc1ccc(O)c(Nc2c(Nc3ccccc3)c(=O)c2=O)c1 +N#CN=C(NCCCN1CCN(c2cccc(C(F)(F)F)c2)CC1)c1ccncc1 +O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCC(c2ccccc2)CC1 +Cc1[nH]nc2c1C(c1ccccc1F)c1c(nc3c(c1N)CCCC3)O2 +Cc1nc(NC(=O)C2(C)CC3c4ccccc4C2c2ccccc23)sc1C +COc1cc(Nc2cccc3c2nc(-c2ccc(F)cc2)n3C)ccc1-n1cnc(C)c1 +COCCN1CCCC(n2nc(C(=O)N3CCOCC3)c3c2-c2cccc(F)c2S(=O)(=O)C3)C1 +CCCCn1c(=O)cc(C(=O)OC2CC3CCC(C2)N3C)c2cc(C)ccc21 +O=C(OC1CN2CCC1CC2)C(O)(CN1CCCC1)c1ccccc1 +c1ccc(Nc2ccc(Oc3nccnc3N3CCNCC3)cc2)nc1 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+[C-]#[N+]c1cc(N2CCc3ncnc(OC4CCN(C(=O)c5ccn(C)n5)C4)c3C2)cnc1OC +Clc1ccc(-c2nccnc2C2CN(c3ncc4ccccc4n3)C2)cc1 +CS(=O)(=O)N(CCN1CCOCC1)c1ccc(Nc2ncc3cnn(C4CCCCCC4)c3n2)cc1 +Clc1ccc(NCc2ccccc2)nc1-c1ccnc2[nH]c(C3CCCNC3)cc12 +CCC(COc1cccc(C(F)(F)F)c1)OC(=O)NCCc1ccccc1 +Oc1cccc(Nc2nc(NCC3CCCO3)c3ccccc3n2)c1 +Cc1c(N(Cc2ccc(F)c(F)c2)S(=O)(=O)N(C)C)sc2ccccc12 +CCN1CCC23Cc4nc5ccccc5cc4CC2(O)C1Cc1ccc(O)cc13 +COc1cc(C(Nc2ccc(C(=N)N)cc2)C(=O)O)ccc1OCc1ccccc1 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc(C(N)=O)cc4)CC3)c2c1 +Nc1ncc(-c2ccc(=O)[nH]c2)nc1-c1ccc(C(=O)NC(CO)c2ccccc2)cc1 +CSc1nccc(N2CCC(N(C)Cc3c(F)cccc3Cl)CC2)n1 +COc1cccc(-n2ncc3c(NN=Cc4ccccc4)ncnc32)c1 +CC(C)(C)C(=O)Oc1cccnc1C(=O)Nc1nccs1 +CCn1c(=O)n(CC2CC2)c(=O)c2[nH]c(-c3cnn(Cc4ccccc4)c3)nc21 +CC(C)(C)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccc(C(=O)O)c2)cc1 +COc1cc(C)c2[nH]c(=O)c3sccc3c2c1-c1ccc(C2(CN)CC2)cc1 +CNCC(O)CN(c1cc(OC)cc(OC)c1)c1ccc2ncc(-c3cnn(C)c3)nc2c1 +c1ncc(-c2cc(CNc3nc(Nc4cc(C5CC5)n[nH]4)cc(N4CCOCC4)n3)on2)cn1 +CCCCOc1nc(N)c2c(n1)N(Cc1cccc(CN3CCCC3)c1)CC(=O)N2 +O=C(NC1CCCCC1NCc1cccc(O)c1)c1ccc(F)cc1 +O=c1[nH]c(-c2ccc(=O)n(CC3CNCCOC3c3ccc(Cl)c(F)c3)c2)no1 +COC(=CC=Cc1cc2cc(Cl)c(Cl)cc2[nH]1)C(=O)NC1CC2CCC(C1)N2C +Cn1nnnc1C(C=CC(O)CC(O)CC(=O)O)=C(c1ccccc1)c1ccc(F)cc1 +CCn1c(C(=O)c2cc(C)cc(C#N)c2)c(C(C)(C)C)c(=O)[nH]c1=O +COc1ccc(Cl)cc1S(=O)(=O)N1COc2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc21 +CCc1cc(NC(=O)NCC2CCCN(CCc3ccc(N(C)C)cc3)C2)cc(-c2nnnn2C)c1 +Cc1cccc(Cl)c1Nc1nc2ccc(N)cc2n2cncc12 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(C(C)=O)C3)cc12 +COC(C)(C)c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1 +CCn1c(Sc2ccc(Nc3c(C#N)cnc4cc(OCCCN(C)C)c(OC)cc34)cc2Cl)nc(C)c1C +Cc1ccc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C2(C)CCOCC2)o1 +CCOC(=O)c1ncn2c1C(C)N=C(c1ccccc1)c1ccccc1-2 +CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(-c2cncs2)c1)C(=O)O +O=c1ccc2ccc(F)c3c2n1CC3CN1CCC(NCc2cc3ccccc3o2)CC1 +CC(CCC(=O)O)Cc1cccc(OCc2ccc3ccccc3n2)c1 +COc1ccc(N(C)c2nc(C)nc3c2CC(C)N3)cc1 +O=C(Cc1ccc(F)cc1)NC1CCN(Cc2ccccc2)CC1 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+CC1CN2c3c(nc4c(-c5nccs5)noc4c3Cl)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CC1CN(CC2CC2)CCN1C(=O)OCC1CCCC(c2cccc(F)c2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCc1cccc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 +CCN1CCc2c(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n[nH]c2C1 +CC(C=CCN(C)c1cc(C(C)(C)C)cc(C(C)(C)C)c1)=CC(=O)O +COc1ccc2cc3[n+](cc2c1OCCCOc1ccc(-c2cc4ccccc4[nH]2)cc1)CCc1cc2c(cc1-3)OCO2 +Cc1ccc(CN2CCC(CC(=O)N3c4ccccc4CC3C)CC2)cc1 +Cc1nnc2sc(C(=O)NC3CN(C(=O)c4ccccn4)C3)c(N)c2c1C +COC(=O)c1ccc(C)c(NS(=O)(=O)c2ccc(C)cc2)c1 +COc1cc2c(cc1O)CCN1Cc3c(ccc(O)c3OC)CC21 +CC(C)c1ccnn1CC(=O)Nc1cncc(C(=O)c2cn(C(C)C)c3ccncc23)c1 +CN(CCC(F)CN1CCN(c2cccc(Cl)c2Cl)CC1)Cc1ccc2c(c1)Cc1ccccc1-2 +Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)CN(c1ccc(F)cc1)C2=O +CC(C)(C)Cc1nc2cc(S(=O)(=O)C(C)(C)CO)ccc2n1CC1CC1 +CC1CC(C(=O)N2CCc3nc(C#Cc4ccccc4)sc3C2)C1 +O=[N+]([O-])c1cccc(S(=O)(=O)NC(P(=O)(O)O)P(=O)(O)O)c1 +CSCCOc1cnc(C(=O)Nc2cccc(C3(C)CCSC(N)=N3)c2)cn1 +Cc1ccc(Nc2ccc([N+](=O)[O-])cc2S(=O)(=O)NC(=O)N2CCCCC2)cc1 +O=C(NC1(CO)CC1)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12 +Fc1ccccc1N1CCN(Cc2nc3ccccc3[nH]2)CC1 +CC(CNc1cc(Nc2cc(Cl)ccc2F)nc2c(C=C3NC(=O)NC3=O)cnn12)N1CCOCC1 +Cc1ccccc1CNc1nc(C)c([N+](=O)[O-])c(-n2ccnc2C)n1 +Cc1cccc(-c2noc(C3CN(C(=O)C4CCC(F)(F)CC4)C3)n2)c1 +COCc1c(N)[nH]cc2nc3ccc(OCc4ccccc4)cc3c1-2 +Cc1cc2c(cc1C(=O)N=C(N)N)S(=O)(=O)CCCC2 +CCCCOc1ccc(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2(O)C#CCCCCC#Cc1cccc2c(=O)cc(-c3ccccc3)oc12 +NC(=O)N(O)CCC#Cc1ccc(CN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)o1 +O=C(O)C1=CC(OP(=O)(O)O)C(O)C(OC(OP(=O)(O)O)(C(=O)O)C(F)(F)F)C1 +CCOc1cc(OCC)n2sc(=NC(=O)c3ccc(Cl)nc3)nc2n1 +CCCCCCCCc1cc(CCCCCCCC)c(C=C2N=C(c3ccc[nH]3)C=C2OC)[nH]1 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)OC2CCOCOC2)cc1 +CCc1nn(Cc2ccc(-c3nc4ccncc4[nH]3)cc2)c(CC)c1CC(=O)O +CC1=CC2Cc3nc4ccccc4c(NCCCCCCCCCCNc4c5c(nc6ccccc46)CCCC5)c3C(C1)C2 +COc1cc(Br)c2c(C(=O)OCC34CCN(CC3)CC4)c[nH]c2c1 +CCC1CCCC(C2(OC(=O)N3CC4CCC(C3)N4CCO)CC2)N1S(=O)(=O)c1ccc(F)cc1 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+O=C(O)c1ccc(CNC(=O)C2NC3(CCCCC3)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)cc1 +Cc1cc(S(N)(=O)=O)c(S(=O)(=O)C(C)C(=O)O)cc1Cl +CN(C)CCCOc1cc(-c2ccccc2)n(-c2ccccc2)n1 +N#CC1(c2cccc(C(F)(F)F)c2)CCC(CNc2ncccc2NC(=O)CC(F)(F)F)CC1 +O=C(NO)c1cnc(N2CC3C(C2)C3NCc2ccc(OC(F)(F)F)cc2)nc1 +Cc1cc(-c2nnn(CC3CCC(CO)CC3)n2)cc(C(=O)NCc2cccc(Cl)c2)n1 +COC(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(-n2cccc2CN2CCNCC2)cc1)c1ccccc1 +COc1ccc2[nH]c(C(=O)c3ccc(OC)c(OC)c3)cc2c1 +COc1cc(OC)cc(N(CCCO)c2ccc3ncc(-c4cnn(C5CCCCO5)c4)nc3c2)c1 +O=C(NC1(CO)CCCCC1)c1cnc(C2CC2)c(OCC2CC2)n1 +O=C1NC(=O)c2c1c1c3ccc(O)cc3[nH]c1c1c2c2ccc(O)cc2n1C1OC(CO)C(O)C(O)C1O +CCCN(CCO)CCCOc1cc2ncnc(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)c2cc1OC +O=C(Nc1ccc(-n2cc(-c3ccncc3)c(-c3ccc(Cl)c(O)c3)n2)cc1)c1ccc(Cl)c(C(F)(F)F)c1 +Cc1cc(COc2ccc(C(=O)NC3(CC(=O)NO)CCN(C(=O)CC(C)(C)C)CC3)cc2)c2ccccc2n1 +COc1ccc(N)cc1CN1CCC(=O)C(C(c2ccccc2)c2ccccc2)C1 +CN(C)CCOc1ccc(C(=O)N2CC(=Cc3ccccc3)C(=O)C(=Cc3ccccc3)C2)cc1 +O=C(NCCCCCS(=O)(=O)N(OCCN1CCOCC1)C1CCCCC1)Nc1ccncc1 +COC12CCC3(CC1(C)C(O)c1cccs1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CCc1ncnc(-c2ccc(C(=O)N3CCn4c(COC)nnc4C3)c(F)c2)c1C#Cc1ccc(N)nc1 +COc1ccc(C2=NN(c3ccc(-c4ccc(O)nn4)cc3)C(=O)C3CC=CCC23)cc1OC +Cc1ccc(-n2cc3c(n2)c(NC(=O)C(c2ccccc2)c2ccccc2)nc2ccccc23)cc1 +Nc1ncnc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)c1C=NOCC(=O)N1CCOCC1 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)C2CC3(CCCO3)CCO2)cc1 +COc1ccc(CS(=O)(=O)C=Cc2c(OC)cc(OC)cc2OC)c(NC(C)C(=O)O)c1 +O=C(C1CCCCC1)N1CCN(C(c2ccc(Cl)cc2)c2cncnc2)CC1 +CNc1cc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2cn1 +COCC(C)Oc1ccc2[nH]nc(-c3cc(N4CCC(CO)C4)ncn3)c2c1 +Nc1n[nH]c2c1c(Nc1ccc(Cl)cc1)nc1ccccc12 +COc1cccc2c1nc1n2CCC(O)=C1C(=O)Nc1c(F)cccc1F +N#Cc1cccc(COc2nn3c(-c4ccccc4)nnc3c3ccccc23)c1 +COc1ccc2cc(CN3CCc4cc(OC)c(OC)cc4C3)ccc2c1 +CS(=O)(=O)c1ccccc1Nc1nc2c(Nc3ccc(C(F)(F)F)cc3)ncnc2s1 +OCc1ccc(-c2nn(Cc3c(F)c(F)cc(F)c3F)c3ccccc23)o1 +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCCCc1ccc(OCC(O)CO)cc1 +CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(-c3ccncc3)n2)cc1 +CC(C)CCNC(=O)c1nc(-c2ccc(CN3CCOCC3)cc2)[nH]c(=O)c1O +NC(COP(=O)(O)OCC1OCCCC1OC(=O)CCc1ccccc1OCc1cccc(Oc2ccc(Cl)cc2)c1)C(=O)O +COc1cccc(C(=O)Nc2ccc(-c3nc4ccccc4[nH]3)cc2)c1 +CN1CCN(CCCn2nc(C3=C(c4cn(-c5ccc6ccccc6c5)c5ccccc45)C(=O)NC3=O)c3ccccc32)CC1 +COc1cc(OC)cc(-c2cc3cnc(NCCCN4CCN(C)CC4)cc3nc2N)c1 +COc1cccc2c(=O)c(C)c(-c3ccc(Cc4ccc(OC(F)(F)F)cc4)cc3)[nH]c12 +CC1(C)Oc2ncnc(N)c2N=C1c1ccc(C2CCCCC2)cc1 +COc1ccc(C=CC(=O)N2CC(CCl)c3c2cc([N+](=O)[O-])c2ccccc32)cc1O +Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)OCC=CCO)O2)c(=O)[nH]c1=O +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCC2)C1 +CC=CC(CC(=O)O)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +COC(=O)c1ccc(OCC(C)(O)C(=O)N2CCc3c(C#N)cccc32)cc1 +CN(C)S(=O)(=O)NC1CCC(Nc2nccc(-c3cnc4c(C(C)(C)O)cccn34)n2)CC1 +COC(=O)C1CCC2(CCC3C4CCc5cc(O)ccc5C4CCC32C)OC1=O +CCN(CCC#N)c1nc(C)nc2c(-c3c(C)cc(OC)cc3OC)c(C)nn12 +O=S(=O)(c1cccnc1)N(CC(F)(F)F)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +Cc1nnc(-c2cccc(-c3cc(Cl)c(C4(C)CS(=O)(=O)N(C)C(=N)N4)s3)c2)o1 +Cc1cc(C)c2c(N)c(C(=O)NN=Cc3cccc4ccccc34)sc2n1 +CN1CCN(c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)CC1 +COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(C)O)CC1)C(=O)C2 +Fc1cc(OC2CCNCC2F)c2nc(-c3nnc4ccccn34)ccc2c1 +COc1ccccc1C1=C(c2cn(CCCN)c3ncccc23)C(=O)NC1=O +Cc1cc(-n2cnnn2)ncc1NC(=O)N1CCN2CC(c3ccc(F)c(C#N)c3C)OCC2C1 +Cn1cc2c(nc(NC(=O)Nc3ccccc3)n3nc(-c4ccco4)nc23)n1 +Cn1c(O)nc2nc3ccc(OCCCC(=O)N4CCN(Cc5ccccc5)CC4)cc3cc21 +CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)c(=O)c1=O +Cc1cc(NC(=O)Nc2cc(F)ccc2F)c2ccccc2n1 +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1cc(F)ccc1F +COC(=O)Cc1c(C)n(C(=O)c2ccccc2Cl)c2ccc(OC)cc12 +CN(C)c1cccc2c(S(=O)(=O)Nc3cnc(Cl)cn3)cccc12 +CN(C(=O)c1ccc2c(c1)nc(NC(=O)c1cccs1)n2CCC(N)=O)C1CCCCC1 +Cc1cc(C)c2c(CCC(=O)O)c(C(=O)O)[nH]c2c1 +CC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4cccc(C(F)(F)F)n4)C3)cc2)s1 +COc1ccc(C2=Nc3c(N)ncnc3OC2(C)C)cc1 +CCN(C)CCc1c(-c2ccccc2)[nH]c2ccccc12 +NS(=O)(=O)c1ccccc1NS(=O)(=O)CCc1ccc(C#CC2CCCCC2)nc1 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+CS(=O)(=O)c1ccc(C2=C(c3ccc(OC(F)(F)F)cc3)CC3(CC3)C2)cc1 +FC(F)(F)c1cccc(Cn2cc(C=NNc3nc(N4CCOCC4)c4sccc4n3)c3ccccc32)c1 +O=C1NC2C(NCc3ccc(Cl)cc3)CCCC2N(Cc2ccc(Cl)cc2)C1=O +CCCCN1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 +O=C(CN1CCN(Cc2ccccc2)CC1)C(O)(c1ccccc1)c1ccccc1 +CCNCc1cc(-c2ccc3c(c2)OCO3)n(S(=O)(=O)c2ccc(C)cc2)c1 +CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCN(C2CCN(C(=O)C3CCCC3)CC2)CC1 +N#CCC1(n2cc(C(N)=O)c(Nc3cncc(Cl)c3)n2)CCN(C(=O)OCC(F)(F)F)CC1 +CC(=O)c1ccc(NC(=O)C2CCC(N3C(=O)C4C5CCC(C5)C4C3=O)CC2)cn1 +O=C(NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1)c1ccc(-n2cccn2)cc1 +CCOC(=O)c1cnc(-n2nc(C)cc2C)nc1Nc1ccc(C)cc1 +Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(F)c(C(F)(F)F)c5)CC4)cc3)c12 +COc1cc(C2c3cc4c(cc3C(CCN(C)CCN3CCOCC3)C3COC(=O)C23)OCO4)cc(OC)c1O +O=c1c2ccccc2ccn1C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O +O=S(=O)(c1ccccc1)C1(CCCN2CCc3ccccc3C2)CCC1 +Oc1ccc(C=Cc2ccc(-c3ccc(Br)s3)s2)cc1 +CCOc1ccc(-c2csc3ncnc(SCCC(=O)O)c23)cc1 +CCCCOc1ccc(S(=O)(=O)N2CCCS(=O)(=O)C(C)(C)C2C(=O)NO)cc1 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+O=S(=O)(c1ccccc1)n1ccc2c3c(ccc21)C1CCNCCC31 +Cc1cc(C)c(NC(=O)c2ccc3nc(Nc4ccccn4)sc3c2)c(C)c1 +CCN(C(=O)C1=CCCC1C(=O)NCc1ccc(C(=N)N)cc1)c1cc(Cl)ccc1C +CCNC(=O)C1OC(n2cnc3c(NC(=O)Nc4cccc(Cl)c4)nc(I)nc32)C(O)C1O +CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)c4cn5cc(C#N)ccc5n4)c3)sc2C1 +NC1=NC(CCc2ccc(Nc3cnc(Cl)nc3)cc2)CO1 +COc1cc(-c2cc(C3CCN(C4COC4)CC3)n(C(C)C)n2)cnc1N +Cc1csc(C#CC23CC4CC(C2)CC(NC(=O)c2ccn(C)n2)(C4)C3)n1 +Cc1nc[nH]c1CN1CCN(C(=O)NC(CC(C)C)C(=O)O)C(Cc2ccccc2)C1=O +COc1ccc(CCOc2c(I)cc(CC(N)C(=O)O)cc2I)cc1 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1(S(=O)(=O)c2cccc3ccccc23)CCCC1 +CN(C)CC=CC(=O)N1CCCc2[nH]c3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn3c2C1 +CN(C(=O)Nc1ccc(-c2ccccc2)cc1)C1CCN(C(=O)N(C)C2CCN(CCCc3ccc(Cl)cc3)C2)C1 +CS(=O)(=O)NC(=O)Cc1ccccc1Oc1ccccc1F +CC(CS(=O)(=O)c1ccc(Oc2ccccc2)cc1)(NCc1ccccc1)C(=O)NO +COc1ccc(-c2cc3nc(NC(C)C)[nH]c(=O)c3s2)cc1 +CN=C(N)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O +N#Cc1ccc(Oc2ccc(Cc3ccncc3)cc2O)c(Cl)c1 +CC(C)C(CN1CCCC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +Cn1ccc(-c2ccc(Cn3cc(C(=O)NC4CCCCC4O)c4ncccc43)cc2)n1 +O=C(NCc1ccc(Cl)cc1Cl)N1CCC(Oc2ccc(F)cc2)CC1 +Cc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3sccc3Cc3ccccc32)cc1 +CN1CCN(CC2CCCN2c2cc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)ccn2)CC1 +O=C(NCCCO)C1C(C(=O)Nc2ncc(Br)s2)C2CCC1C21CC1 +CSc1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 +CCNC(=O)C1OC(n2cnc3c(NCc4ccccc4OC)ncnc32)C(O)C1O +CC1(C)Nc2c(cc(-c3cccn4nccc34)c3c2CCC3)C(C)(C)C1=O +Nc1nonc1C(=O)NN=C1c2ccccc2-c2nc3nonc3nc21 +COCC(NC(=O)Nc1cc2[nH]nc(OC)c2c(C)n1)c1ccccc1 +N#Cc1cccc(Cn2cccc2C=CC(=O)CC(=O)C(=O)O)c1 +CC(C)CC1C(=O)NC(C(=O)c2c[nH]c3ccccc23)Cc2ccc(cc2)OCCCCCC1C(=O)NO +CCSc1ccc(CNC2CCNCC2NC(=O)CNC(=O)c2cc(C(F)(F)F)ccc2N)cc1 +O=S(=O)(c1cccc(Cl)c1)N1CC2CC1CN2CCOc1ccccc1-c1ccccc1 +O=C(Nc1cc(-c2ccccc2)no1)c1ccc2cc3n(c2n1)CCCNC3=O +COc1cc(Br)c(-n2c(C)nc3c(-c4ccccc4C(F)(F)F)nc(C)nc32)c(OC)c1 +COc1ccc(N(CCCCCCC(=O)NO)c2ccccn2)nc1 +Cc1cccc(-c2csc(NC(=O)CCCCCCC(=O)NO)n2)c1 +CCCc1c(C(=O)Nc2cc(S(=O)(=O)N(C)C)ccc2C)cnn1-c1ccc(Cl)cc1 +C=CCC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(P(=O)(c4ccccc4)c4ccccc4)cc3)CC21C +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1ccc(-c4ccccc4)cc1)O2)C(C)=CC(C)(C)N3 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(CNC(C)C(=O)O)cc2C)ncn1 +COc1ccc(-c2cncn2-c2cc(OC)c(OC)c(OC)c2)cc1F +CN1CCN(c2ccc3c(c2)N(S(=O)(=O)c2ccc4ccccc4c2)CCC3=O)CC1 +OCC1OC(c2ccc(C(F)(F)F)c(Cc3ccc(-c4ccsc4)s3)c2)C(O)C(O)C1O +CC(=O)OC(COP(=O)(O)O)C(OC(C)=O)C(=O)NO +COC(=O)CCC(=O)Nc1nnc(S(N)(=O)=O)s1 +COc1ccc2c(c1)c1c(n2C)CN(c2ccc(OC)c(OCCN3CCCCC3)c2)C1=O +CN1CC2CC1CN2c1ccc(-c2ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn23)c(Br)c1 +CCOC(=O)c1c(Cc2cccc(Cl)c2)[nH]c2c1cc(O)c1ncccc12 +CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2CC2CCOCC2)cc1 +COc1cc(N2CCC(Oc3ccc(N4N=C(C(F)(F)F)C(C)C4CC(=O)O)cc3)C(F)C2)c(Cl)cn1 +CC(C)(C)NC(=O)c1cc(C(F)(F)F)ccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +CC(=O)NC1CCC(CCN2CCC(c3noc4cc(F)ccc34)CC2)CC1 +N#Cc1ccc(Nc2nc(Oc3ccc(Cl)cc3Cl)c3ccccc3n2)cc1 +O=C(O)CC1CC1c1ccc(OCCc2ccc3c(n2)NCCC3)cc1 +CCN(CC)CCC(=O)Nc1cc(-n2cccn2)c2[nH]c3c(-n4cccn4)cc(NC(=O)CCN(CC)CC)cc3c2c1 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)CN1CCC(Nc2nccc(Oc3c(C)cc(C#N)cc3C)n2)CC1 +COCC(NC(=O)N1CC(=O)Nc2cc(OC)cnc21)c1ccc(OC(F)(F)F)c(F)c1 +O=C(CCCCCCC(=O)Nc1cc2ncnc(Nc3cccc(Cl)c3)c2s1)NO +COCC(C)Oc1ccc2[nH]nc(-c3cc(N4CCC(F)(F)CC4)ncn3)c2c1 +O=C(O)COc1cccc(C=C2SC(=O)N(CC(=O)O)C2=O)c1 +CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC(C)C +COc1cccc(C(=O)Nc2cccc(C#Cc3cc(C(=O)N=S(=O)(CCCO)CCCO)cnc3N)c2)c1 +CCOC(=O)C1=C(C)N=C(C)C(=C(O)OCC)C1c1cccc(-c2cccnc2)c1 +COc1ccccc1COCCCOc1ccc(N2C(=O)CNCC2COc2ccc3c(c2)N(CCC(=O)O)CCC3)cc1 +C#CC(C)(C)Nc1ccnc2sc3c(=O)n(-c4ccc(C)cc4)cnc3c12 +O=C(c1ccc2cc(OCCCN3CCCCC3)ccc2n1)N1CCC1 +COc1ccccc1CNC(=O)c1cccc(NCc2nnc(-c3ccncc3)[nH]2)c1 +CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Cl)cc1Cl)C(=O)O +COc1ccccc1N1CCN(CCC(=NO)c2ccc(C)s2)CC1 +CC(=O)N1C(=O)C(C)C2C1CCN2C(=O)C1CCCN1S(=O)(=O)c1cccc2c(N(C)C)cccc12 +OCC1C(O)C(O)C(O)c2nc(COc3ccccc3)cn21 +CCOC(=O)C(CCc1ccccc1)NC(C)C(=O)N1CCCC1C(=O)O 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+CSc1ccc(-c2ccc(C(NC(CC(C)C)C(=O)NCC#N)C(F)(F)F)cc2)cc1 +CN1CCC(Nc2ccc3ncc(-c4cnn(-c5ncc(F)cn5)c4)n3n2)CC1 +CN(C)C(=O)CN1CC=C(c2[nH]c3nccc4c3c2CN(C)c2ccc(F)cc2-4)C(C)(C)C1 +CC(=O)Nc1nc2ccc(-c3cccc(NS(C)(=O)=O)c3)cn2n1 +COCCOc1ccc2[nH]nc(-c3cc(N4CCOC(C)C4)ncn3)c2c1 +O=C(Nc1nnc(CCc2ccccc2)s1)c1ccc(I)cc1 +S=C(c1cn(CCOc2ccccc2)c2ccccc12)N1CCCC1 +COc1ccc2cc(C(O)CCN3CC=C(Cc4ccccc4)CC3)ccc2c1Cl +NC1CCC(Nc2ccc3ncc(-c4cnc(Nc5ncccc5F)nc4)n3n2)CC1 +COC(=O)C(Oc1cccc2sc(C(=N)N)cc12)c1ccccc1 +COc1ccc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)cc1 +CC(=O)N(C)C1CCC(C(C(=O)N(C)C)C(N)C(=O)N2CCC(F)C2)CC1 +COc1cc(OCc2csc(C3(O)CCC4(CC3)OCCO4)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CCCCCCOc1ccc(CC=CC(SCC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(=O)O)C(O)CCCC(=O)O)cc1 +O=C(NCCc1cccnc1Cl)c1ccnc2[nH]c(-c3ccoc3)nc12 +COc1cc(-c2ccccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)ccc1C#N +O=C(NCCc1ccc(OCCN2CCCC2)c(Br)c1)c1ccc(Br)o1 +COC(=O)c1cccc(C2CCCN2C(=O)c2cc(Cl)c(O)cc2O)c1C +COc1cccc(CNC(=O)c2cc3ccc(-c4cn[nH]c4C)nc3[nH]2)c1 +O=C(O)Cc1nc(NC(=O)c2nc(Sc3ccccn3)ccc2Sc2ccc(F)cc2)sc1Cl +Cc1cc(NN=Cc2ccc(OC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)c2ccc(C)c(C)c2n1 +CC1(c2ccccc2)CCCN(C(=O)NCc2ccc(-c3ccccn3)cc2)C1 +NC(CCCCB(O)O)(CCN1Cc2ccccc2C1)C(=O)O +CNCCN1C(=O)C(OC(C)=O)C(c2ccc(OC)cc2)Cc2c1cccc2C(F)(F)F +O=c1c(O)c(-c2ccc(O)c(O)c2)oc2ccc3ccccc3c12 +CC1(c2cc(NC(=O)c3ncc(Cl)cc3Cl)ccc2F)COCC(N)=N1 +C1=C(c2cccs2)CN(c2ncnc3cc(N4CCOCC4)ccc23)CC1 +Cc1cc(CC(NS(=O)(=O)c2ccccc2C#N)c2nc3ccccc3[nH]2)ccc1C1CC(=O)NS1(=O)=O +CC(=O)N1Cc2cc(Nc3ncc4c(=O)n(-c5ccccc5Cl)c5nccn5c4n3)ccc2C2(CC2)C1 +CCNCCCCNCC1CC1CNCCCCNCC1CC1CNCCCCNCC +COc1ccc(Nc2nc(-c3ccc4[nH]ncc4c3)cn3ccnc23)cc1OC +Nc1nc(CCl)nc(N(c2ccccc2)c2ccccc2)n1 +CC(C)(CCCCOc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccccc2)n1)C(=O)O +CN1CCN(C(=O)c2ccc(NC(=O)Nc3ccc(-c4nc(OC5CCOC5)nc(N5CCOCC5)n4)cc3)cc2)CC1 +C#Cc1cccc2[nH]cc(C(=O)c3ccc(Cn4c(C)nc5cnccc54)c(F)c3)c12 +COc1cc(C(=O)c2c(-c3ccccc3)[nH]c3ccc(Cl)cc23)cc(OC)c1OC +CN(Cc1ccsc1)C(=O)C12CC3CC(CC(C3)C1)C2 +CC1CNC(=O)c2[nH]c3ccc(C(=O)Nc4nc(C(=O)N(C)C)cs4)cc3c21 +O=C(Nc1ccc(OC(F)(F)F)cc1)N(Cc1cccc(-c2nccs2)c1)C1CC1 +COc1cc(C(=O)Oc2ccc(-c3cc(=S)ss3)cc2)ccc1OC(=O)CCCO[N+](=O)[O-] +Cn1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1=O +Cc1c(C(=O)NCCO)sc2ncnc(Nc3ccc(F)cc3OCC(F)F)c12 +CCn1c(=O)c2c(nc(Cc3cccs3)n2C)n(Cc2cccs2)c1=O +Cc1nc(N2CCC(O)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +Cc1c(N(Cc2cccc(C(F)(F)F)c2)S(=O)(=O)c2ccc(C(=O)O)cc2)sc2ccccc12 +CS(=O)(=O)CCC1OCCC2(S(=O)(=O)c3ccc(C#N)cc3)C3=C(OCC12)C(F)(F)C=CC3=O +CC(=O)N1CCc2ccc(COCCCCN3CCN(c4cccc5sccc45)CC3)cc2C1 +COCc1cccnc1-n1cc(CN2CCC3(CC2)OCCc2cc(Cl)sc23)c(C)n1 +CNC(=O)Nc1ccc(O)cc1OCC(O)CN1CCC2(CC1)Cc1cc(F)ccc1O2 +O=C1NC(=O)C(c2ccc(Oc3ccccc3)cc2)(N2CCCN(C(=O)Cc3cccs3)CC2)C(=O)N1 +O=C(NCc1ccccc1)c1cnc(NCCCN2CCCC2)nc1NCC1CCCCC1 +COc1ccc(C(C)(C)c2cnc(SCCOc3ccc(-n4cncn4)cc3)n2-c2ccc(F)cc2)cc1OC +CC(NC(=O)C(S)Cc1ccccc1)C(=O)N1CCCCC1C(=O)O +CCCCCCCCc1ccc(OCC(=O)Cn2cnc3ccc(C(=O)O)cc32)cc1 +CCc1c(Cc2c(Cl)cccc2Cl)nc(SCC(=O)c2ccccc2)[nH]c1=O 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+CN1C(=N)NC(C)(c2cc(-c3ccc(-c4nnco4)[nH]3)ccc2F)CS1(=O)=O +Cc1nc(-c2cc(Cc3ccc(S(C)(=O)=O)cc3)cnc2Nc2ccc(N)nc2)c2nc[nH]c2n1 +Cc1cccnc1-c1cc(N2CCC(NC(=O)CC(C)(C)O)CC2)ncc1Cl +COc1ccc(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc1 +CCC(=O)Nc1nc(-c2ccc3c(c2)OCO3)cc(-c2ccc3c(c2)OCO3)n1 +CC1(C)CN=C2C(=O)c3cc(S(=O)(=O)N4CCCC4COc4cc(Cl)ccn4)ccc3N2C1 +CC(=O)c1nn(CC(=O)N2C(C(=O)Nc3nccc(C(F)(F)F)n3)CC3CC32)c2ncccc12 +CC(C)(C)OC(=O)N1CCC(Sc2ncnc3c2cnn3-c2ccc(S(C)(=O)=O)cc2)CC1 +COc1ccc2c(C#N)cn(-c3ccc(C(=O)O)c(O)c3)c2c1 +CN(C)CCn1nc2c3c(c(NCCC=CCCN4CC4)ccc31)C(=O)c1ccncc1-2 +O=C(O)C(=Cc1ccc(Oc2ccccc2Br)cc1)NC(=O)c1ccccc1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CO2)c1Cl +O=C(NCc1cc(Cl)ccc1-n1cnnn1)C1CCNN1C(=O)C(O)c1ccccc1 +O=S(=O)(c1ccc2[nH]c(-c3cc4ccccc4nc3O)cc2c1)N1CCNCC1 +CC1=C2CCc3cc(OCc4ccccc4Cl)ccc3N2CCC1=O +CC(C)Sc1nc(Nc2cccc(O)c2)c2cnn(CC(Cl)c3ccccc3)c2n1 +CC(c1ccccc1)(c1ccccc1)c1nc(-c2ccc(F)cc2)c(CC(=O)O)s1 +O=C(COC1CC(CNc2ccccn2)N(C(=O)OCc2ccccc2)C1)NCC(NS(=O)(=O)c1ccccc1)C(=O)O +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C#CCOCc1ccc2c3cccc4cccc(c5cccc1c52)c43 +COc1ccc(C(C#N)(CCCCCN2Cc3cc(OC)c(OCCn4ccnc4)cc3C2)Sc2ccc(C)cc2)cc1OC +CC(NC(=O)c1cc(C(=O)N2CCCC2C(F)(F)F)c2n1CCOC2)c1ccc(F)cc1 +CC(=O)c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1 +Cn1cc(C2=C(c3coc4ccc(F)cc34)C(=O)NC2=O)c2cc3c(cc21)OCO3 +NC(CC1c2ccccc2Oc2ccccc21)(C(=O)O)C1CC1(F)C(=O)O +COc1ccc(CNc2nnc(N3CC=CCC3)c3ccc(C#N)cc23)cc1Cl +CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCCCC2)c1 +CC(C)N1CCC(C(=O)Nc2cc(Oc3ccc4c(c3)nc(Nc3cccc(C(C)(C)C)c3)n4C)ccn2)CC1 +CN(C)CCCn1c(NC(=O)c2ccc3nc4n(c3c2)CCCNC4=O)nc2ccccc21 +CCCC(O)C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +CC1=C(c2cc(C(C)(C)N3CCCCC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CCCC1C +CCN(c1nc(C)cc(-c2c(C)cc(C)cc2C)n1)c1ccc(C(C)C)cc1Br +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)NCc5ccc(Oc6ccc(F)cc6)cc5)cn4c3)cc2)CC1 +CCC1(CC(O)(Cc2cc3c(C)cc(C#N)cc3[nH]2)C(F)(F)F)CCCc2ccccc21 +O=C1c2ccccc2S(=O)(=O)N1CCCCN1CCN(c2ccc(Cl)cc2)CC1 +Cc1cc(C)c(N2CCCn3c2nc(C(F)(F)F)c3CN2CCSCC2)c(C)c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4cccc(N5CCCCC5)c4)nc23)N1 +CCOC(=O)C1(C(C)=O)Cc2ccc(C3(O)CCC4C5CCc6cc(O)ccc6C5CCC43C)cc2C1 +Cc1nccn1Cc1c(C(N)=O)nc2n1CCOc1ccc(C#CC(C)(C)O)cc1-2 +Nc1nc2c(s1)C(C(=O)NCc1ccc(Cl)cc1Cl)CCC2 +COc1ccc(Nc2nc(-n3c(C)nc4ccccc43)cs2)cc1 +CCCCCCCCCCCCCCCCNC(=O)OCC1(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CCCC1 +CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(=O)O)c2ccccc2Cl)cc1 +Cc1c(C(=O)NCCc2ccc(Cl)cc2)nn(-c2ccc(F)cc2F)c1-n1cccc1 +Cn1c(CC(=O)Nc2ccc(F)cc2)nc(N2CCOCC2)cc1=O +Oc1noc(C2CCNCC2)c1Cc1ccc(-c2ccccc2)cc1 +CC1(c2nc(NC(=O)c3ncc(OCC(F)(F)F)nc3N)ccc2F)N=C(N)OCC1(F)F +COc1cc(CC(C)(C)C)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CCCC1CCNc2cc3nc(O)cc(C(F)(F)F)c3cc21 +CCCCNC(=O)C(C)CC(O)C(N)CC(CNC(=O)c1cn(CC)c2ccccc12)C(C)C +NC(=O)c1ccc(-c2cc(-c3scc4c3OCCO4)cnc2N)cc1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(C#N)cc1F +CCCCc1nc2ccc(C3C4C(=O)OCC4ON3C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(C)n1c(=O)ccc2cnc(NC3CCC(NC(=O)NC4CCCC4)CC3)nc21 +CNc1nc(-c2ccc3c(N)n[nH]c3c2)cc(N2CC(C(=O)Nc3ccccc3)CCC2C)n1 +O=C1c2c(ccc(O)c2O)CN1Cc1cc(Cl)c(F)cc1F +Cn1c2c(c3ccc(N4CCN(CCc5ccccc5)CC4=O)cc31)C1CCC(C2)N1 +CNc1nc(Nc2cc(OC)c(-c3nc(C)no3)cc2Cl)ncc1C(F)(F)F +O=S(=O)(c1ccc(C(F)(F)F)cc1)c1cccc2oc(N3CCNCC3)nc12 +Cc1c(CN2CCC(N3Cc4cccc(C(N)=O)c4C3=O)CC2)cnn1C +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(Oc2ccc(C#N)cc2)C1 +COc1cc2c3c(c4cc(O)ccc4c2cc1OC)CC1CCCN1C3 +c1ccc2nc(N3CC(Oc4nccnc4-c4ccc(OCC5CC5)nc4)C3)ccc2c1 +Cc1ccc(C(=O)N2CCC(F)(c3ccc(C#N)cn3)CC2)cc1NC(=O)c1ccc(NC(C)C)nc1 +COc1cccc(Cn2cc(C)c3cc(F)cc(C=CC(=O)NS(=O)(=O)c4ccc(F)c(F)c4)c32)c1 +CCNc1nc(Nc2ccc(C#N)cc2)nc(Oc2ccc3ccccc3c2Cl)n1 +COc1ccc2[nH]cc(CCNC(=O)CCCCCCNc3c4c(nc5cc(Cl)cc(Cl)c35)CCCC4)c2c1 +C=C(c1ccccc1)c1cc2c(cn1)C(C)(C)CN2C(=O)CN1CC(C)NCC1COC +Cc1cc(C)cc(Oc2ccc(CCC(=O)O)c(C(=O)NC(CC(C)C)c3cc(C)cc(C)c3)c2)c1 +CCC(=O)Nc1cc2c(Nc3ccc4c(c3)CCN4Cc3ccccc3)ncnc2cc1OC +CCOC(=O)c1c(CN(CC)Cc2ccccc2)nc2ccccc2c1-c1ccccc1 +Cc1cc2n[nH]c(=O)n2c2cc(-c3ccc(C(=O)N4CCOCC4)cc3)ccc12 +COc1cccn2c(C(=O)N3CCCCC3)c(C(F)(F)F)nc12 +O=P(O)(O)C(CCc1cccc(Oc2ccccc2)c1)S(=O)(=O)O +CNC(=O)c1ccccc1-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc21 +COc1cccc2c(C(=O)NC(C)Cc3ccccc3)c(C)n(CCN3CCOCC3)c12 +CCN(CC)C1CCN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCCC3)CNC5=O)nc2)CC1 +O=C(NCCCCCCNc1c2c(nc3ccccc13)CCCC2)c1cc2ccccc2o1 +C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC +Nc1nc(-c2cc(F)cc(F)c2)nc2sc(CN3CCOCC3)cc12 +COc1ccc(OCCN(CC(=O)NCc2ccccc2)Cc2ccc(F)cc2)cc1OC +Cc1cc(-c2c(C(N)=O)nc3n2CCOc2cc(F)c(C#CC(C)(O)c4noc(C)n4)cc2-3)[nH]n1 +Cc1nnc(CNc2c(F)c(OCC3CC3c3ccccn3)nc3ccnn23)s1 +Cc1[nH]n(-c2ccc(I)cc2)c(=O)c1N=Nc1c(O)cc(S(=O)(=O)O)c2ccccc12 +O=C(Nc1ccccc1-c1cn2c(CN3CCC(O)C3)csc2n1)c1ccc2ccccc2c1 +COCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCCCO)C(C)C)ccc1OC +O=c1c2c([nH]c3cc([N+](=O)[O-])ccc13)CCCC2 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCCC1 +Cc1ccc(F)cc1Cc1ccc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3NC3CCOCC3)c2c1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCC(C(=O)O)CC3)cc12 +CC(NC(=O)CC#N)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 +CCCCCCCCCCCCCCOc1ccc(C(=O)N(Cc2cccc[n+]2CCC)C(C)=O)cc1OC +COc1cc2c(cc1OC)-c1c3c(cc4c1C(C2)N(C)CC4)OCO3 +O=C(Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +OCC1OC(n2cnc3c(NCCCCc4ccccc4)ncnc32)C(O)C1O +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)O)C(CS)Cc1cccc(-c2ccccc2)c1 +O=C(Nc1ccc(C(=O)c2ccc(Cl)cc2)c(Cl)c1)C1=C(O)c2ccccc2S(=O)(=O)N1 +CCOc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCN(CCS(C)(=O)=O)CC4)nc12 +COc1cc(C)cc2cc(-c3c(CN4CCCC4)c(CN4CCNCC4)n4ncnc(N)c34)sc12 +COc1cc2cc(C)[nH]c2cc1NC(=O)c1cnn2cccnc12 +C=CC(=O)Nc1cccc(-n2c(-c3nc(-c4cnn(C5CCN(C)CC5)c4)cnc3N)nc3cnccc32)c1 +Cc1cccc(C)c1N1CC(CN2CCC(F)(F)CC2)(C(=O)Nc2cc(Cl)cc(C(F)(F)F)c2)C(C)C1=O +CC1CN(c2ccc(F)c(NS(=O)(=O)c3ccc(-c4ccoc4)cc3Cl)c2)CC(C)N1 +COc1ccc(CCn2c(=O)c3ccccc3c3nc4ccccn4c32)cc1 +CCN(CC)C(=O)c1ccc(N(c2cccc(CO)c2)C2CCN(Cc3ccccc3)CC2)cc1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CN(C)C)cn1 +CNC(=O)c1cncc(NC(=O)c2cc(NC(=O)c3cccc(C(C)(C)C#N)c3)ccc2C)c1 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+COc1ccc(-c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C)cc3)n2)cc1OC +O=C(Cn1c(-c2ccccn2)nc2ccccc21)Nc1ccc(Cl)cc1 +O=C(O)CC(COc1ccc(-c2nc3ccccc3n2Cc2ccccc2)cc1)n1c(-c2ccccc2)nc2ccccc21 +COc1cc(CNCC(C)C(=O)N(Cc2cc(Cl)c3c(c2)OCCCO3)CC(C)C)ccc1F +Cc1cc(-c2c(F)cc3c4nn(CCCN(C)C)c(=O)c-4cn(C4CC4)c3c2F)cc(C)n1 +CCCC(CO)NCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1F +COc1nccc2cc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)ccc12 +CCc1ccc(-c2cc3ncn(C4CCN(C(=O)N(C)C5CCN(C6CCOCC6)C5)C4)c(=O)c3s2)cc1 +COCc1ncn(C2=NCC(=O)N3CCc4c(ccc(F)c4C4CC4)C3=C2)n1 +CN(Cc1ccc(C(=O)O)cc1)CC1CCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1 +COc1cc(CN(c2ccc(C#N)cc2)n2cnnc2)cc(Cl)c1O +CC(Cc1cc(C(=O)Oc2ccc(C(=N)N)cc2F)cs1)C(=O)O +CN(C)CCCNc1c2ccccc2nc2c(Cl)ccc([N+](=O)[O-])c12 +C=CC(=O)Nc1nc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCN(C)CC1 +CN(c1ncc2cccc(-c3cc4c([nH]3)CCNC4=O)c2n1)C(C)(C)C +c1ccc(CCCCNCCOc2cccc3[nH]ccc23)cc1 +Cc1nc(C)n(-c2cc(C3CC3c3nc4ccccc4n3C)nc(N)n2)n1 +CC(C)c1ccc2nc3c(nc2c1)C(=O)c1ccncc1C3=O +CC1CN(c2ncc(NC(=O)CO)cc2Cl)CCN1c1nc2c(-c3ccc(F)cc3)cc(C(F)(F)F)cc2[nH]1 +CC1CNC(=O)c2[nH]c3ccc(C(=O)Nc4nc(C(=O)NCCC(N)=O)cs4)cc3c21 +Cc1ncccc1NC(=O)c1ccc2c(c1)C=CC1CC(O)(C(F)(F)F)CCC21Cc1ccccc1 +CCC(C)C(NCC(N)CS)C(=O)NC(CNC(CCSC)C(=O)O)Cc1ccccc1 +C=CC1CN2CCC1CC2C(OCCc1cn(CCCc2ccccc2)nn1)c1ccnc2ccc(OC)cc12 +Cc1nsc(-n2nccn2)c1C(=O)N1CC(Oc2cc(C#N)ccn2)CCC1C +COc1cc(CCc2ccccc2OCc2cc(OC)c(OC)c(OC)c2)cc(OC)c1OC +CCNC(=O)N(CCCN(C)C)C(=O)C1CC2c3cccc4c3c(cn4C)CC2N(C)C1 +CSc1nc2c3ccccc3ccn2c(=N)c1S(=O)(=O)c1ccccc1 +COc1ccc(-c2cnc(C(=O)N3CCN(c4cnc5ccccc5c4)CC3)nc2-c2ccc(F)cc2)cc1 +Cc1c(F)ccc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)c1Cl +COc1cc(-c2cnn(C)c2C)ccc1Nc1ncc2ccnc(N3CCC4(COC4)C3)c2n1 +CC(C)CN(C)Cc1ccc(-c2ccccc2S(=O)(=O)N2CCCC2)cc1 +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCN2CCCC2C1 +Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnn(C2CC2)c1N1CCC(N)C(F)CC1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(N3CCCCC3)nc21 +CC(C)C1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(C)(C)C(=O)O)cc3)c2)C1 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+O=C(Cc1cccc2ccccc12)Nc1cn(C2CCC2)cn1 +CCOC(=O)c1cc2ccc(OC3CCCCCC3)cc2oc1=O +CCCc1c(OCCCOc2cc(O)c(-c3ccccc3)cc2CC)cccc1Oc1ccccc1Cc1nnn[nH]1 +O=C(Nc1cnc2ccccc2c1)c1cccc(-n2cnnn2)c1 +CCCCCCCCCCCCCCNC(=O)C1CSC(c2ccc(OC)c(OC)c2)N1 +CNC(=O)c1cc(Cl)c(Nc2ncc(C(F)(F)F)c(NC)n2)cc1OC +CC(=O)c1cn(CC(=O)N2CC(F)CC2C(=O)NCc2cc(-c3nnn[nH]3)cc(Cl)c2F)c2ccccc12 +CN(C)CCCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12 +CC(C)c1nc2c(c(C3CCCCC3)c1C(=O)c1ccc(C(F)(F)F)cc1)C(O)CC1(CCC1)C2 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCC(N(C)C)C3)cc2c1=O +COc1ccccc1C(=O)OCC#CCSc1nnc(-c2cccc3ccccc23)o1 +CCC(=O)C1OC(c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)C(O)C(O)C1O +CCc1ccc(Cc2c(Cl)ccc3c2COC32OC(COC(C)=O)C(O)C(O)C2O)cc1 +COc1cc(Nc2nc3cccc(-c4ccc5ncccc5c4)c3o2)cc(OC)c1OC +COc1cc(-n2cncc2-c2ccc3c(ccn3C)c2)cc(OC)c1OC +COc1cc2nccc(Oc3ccc4nc(NC(=O)c5ccc(F)cc5)sc4c3)c2cc1OC +COCCOCc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 +CC(=O)OCC1OC(Oc2ccc(C=NNC(N)=S)cc2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +CC(=O)Nc1cc(Oc2ccc(CNC(=O)Nc3cc(C)c(Cl)cc3OCCN(C)C)cc2C)ccn1 +CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(C(=O)O)ccc12 +CCCSC(=O)C(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +CC(NC(=O)c1ccc(C#Cc2ncccc2F)cn1)C(C)(C)O +CN1CC2CC(OC(=O)C(c3ccccc3)c3ccccc3)CC1C2 +CC1(N)CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1 +COc1cc(C=C2CCCCN3C2=NOCC3c2ccc(F)cc2)ccc1-n1cnc(C)c1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCN2CCOCC2)CCCC1)c1ccc([N+](=O)[O-])cc1 +COc1ccc2c(c1)C13CCN(CC4CC4)C(C2)C1Cc1sc(NC(C)=O)nc1C3 +O=S1(=O)C=Cc2cc(-n3nncc3-c3cccc(F)c3)ccc2O1 +Cc1c(C(=O)NCCCCCCCCNC(=O)c2ccccc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(Nc1ccc(O)cc1C(F)(F)F)c1cc(NC2CCCCC2)ncn1 +COCCOCOc1cc(C)c(-c2ccc3cc(C(=O)O)ccc3c2Cl)cc1C12CC3CC(CC(C3)C1)C2 +CNc1ccccc1C(=O)OC1C(C)=CC23C(=O)C(C=C(CO)C(O)C12O)C1C(CC3C)C1(C)C +Cc1cc(C)c2nc(-c3cnc(NCCCC4CCN(C)CC4)nc3C)[nH]c2c1 +Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCNC1CCCC1 +COC12COC(c3ccc(Cl)c(Cc4ccc(OCCOC5CC5)cc4)c3)(O1)C(O)C(O)C2O +O=C(C1CCN(Cc2ccncc2)CC1)N1CCC2(CC1)C(=O)NCN2c1ccccc1 +COc1ccccc1N1CCN(CCCNC(=NC#N)c2ccccn2)CC1 +CN(C)Cc1nnc(-c2ccc3[nH]nc(-c4ccc(F)cc4)c3c2)[nH]1 +O=C(Nc1ccc(O)cc1O)c1ccc2c(-c3nc4ccccc4[nH]3)n[nH]c2c1 +CC(C)CC(Nc1ccc(C(=O)NCCC(=O)O)cn1)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1 +COC(=O)c1sc(C(C)(C)C)cc1NC(=O)Nc1ccc(Cl)cc1 +CCC(CC)c1nc(-c2ccc(OCCCN3CCCN(C(=O)C(C)NC(=O)c4ccco4)CC3)cc2F)no1 +CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCCN2CCNC(COC)C2)cc1 +Cc1cc(-c2c(-c3cccc(OC(F)(F)F)c3)cc3n2C(CCN)CNC3=O)ccc1F +N=C(NO)c1cccc(C#Cc2c(N)ncc3ccc(Cl)cc23)c1 +COc1ccc(Cn2cnc3c2CC(C(=O)O)N(C(=O)C2(c4ccccc4)CCCC2)C3)cc1C +COc1cccc(-c2nn(C(C)C)cc2C(=O)Nc2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)c1 +CC(C)C(Cc1ccc(C(F)(F)F)cc1)C(=O)NCC1(C2CC2)NC(=O)NC1=O +NCc1cccc(C2CCN(C(=O)c3ccc(C#Cc4cccs4)o3)CC2)c1 +COC(=O)CCCCN(C(=O)C(C)C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +COc1ccc(CCC(=O)O)cc1-c1cc2c(cc1C)C(C)(C)CC(=O)N2C(C)C +NCC(=O)Nc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +CCc1cc(Cc2cnc(N)nc2N)cc(CC)c1OCCOCc1ccccc1 +CN1CCc2nc(C(=O)NC3CC(C(=O)O)CCC3NC(=O)c3cc4cc(Cl)ccc4[nH]3)sc2C1 +COc1ccc(Cl)cc1N1CCN(C(=O)c2oc(C)nc2-c2ccccc2F)CC1 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+O=c1ccn(C2C(O)C(O)C3(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)CC23)c(=O)[nH]1 +CCN1CCCC1CNC(=O)c1c(O)c(Br)cc(N)c1OC +Cc1ccc(N2CCc3ncnc(NC(C)c4cccc(F)c4)c3C2)nc1 +CNc1ncnc2c(Nc3ccccc3C)nc(N3CCNCC3)nc12 +Cc1cc(CN2CCN(C)CC2)ccc1C(=O)Cn1ncc(OCc2ccc(Cl)cn2)cc1=O +CC1=C(c2nc(-c3ccc(C#N)cc3)cs2)C(c2ccc(Oc3ccccc3)nc2)NC(=O)N1 +Cc1cc(-n2ccc(N3CCNC3=O)n2)c2c(n1)N(c1ccc(OC(F)(F)F)cc1C)CC2 +CN1C(=O)CC2CN(CC(=O)Nc3ccc4c(c3)CC3(C4)C(=O)Nc4ncccc43)c3cccc1c32 +Cc1noc(-c2cc3cc(-c4cc(C(=O)NCc5ccc(C(=O)O)cc5)ncc4C)ccc3[nH]2)n1 +CCCCCCCCc1ccccc1CCCCCCCC(=O)C(F)(F)F +CCCS(=O)(=O)NCc1ccc2c(c1)CC(C(=O)N(C)C(CN1CCC(O)C1)c1ccccc1)O2 +Nc1nc2c(-c3ccc(C(F)(F)F)cc3)cccn2n1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCC(O)CF +COc1cccc(-c2cccc(C3(C)COCC(N)=N3)c2)c1 +O=C(c1cc(-n2ccc3ccccc32)c(O)cc1O)N1CCc2ccccc2C1 +Cc1cc(-c2c(C(N)=O)c3cc(F)c(OC(F)F)cc3n2C2CCCCC2)ccc1NS(=O)(=O)C(C)(C)C +Clc1ccc(-c2nn(Cc3ccccc3)c3c2CNCC3)cc1 +CC(=NOCC(=O)O)c1ccc(Sc2cc(F)cc(C3CCOCC3)c2)cc1 +C=CCn1c(=O)c(-c2cccc([N+](=O)[O-])c2)nc2ccccc21 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+O=C(c1c2ccccc2cc2ccccc12)N1CCC(N2CCCC(C(=O)N3CCOCC3)C2)CC1 +O=C1CNC(=O)N1Cc1cccc(CCCCOCCCCCCNCC(O)c2ccc(O)c(CO)c2)c1 +CCN1CCN(c2cn(S(=O)(=O)c3ccc4ccccc4c3)c3cc(Cl)ccc23)CC1 +Cn1cnc2cc(-c3ccc(C(C)(C)O)nc3)nc(OCc3ccncc3)c2c1=O +O=c1c(-c2ccc(F)cc2)c2ccccn2c(=O)n1CCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +CCCCCCCCOC(=O)c1cc(O)c(=O)c2c(O)c(O)c(OC)cc2c1 +CCC(C1CC1)n1nc(C)nc(Nc2cc(C)c(C#N)cc2C)c1=O +CC1C2CCC3C4CC=C5CC(N(C)C(=O)c6ccc(C#N)cc6)CCC5(C)C4CCC32CN1C +COc1cccc(Oc2ccc3c(NCCCNCc4cccc(OC)c4O)ccnc3c2)c1 +COc1ccc(-c2c[nH]c3ncc(-c4cnc(N)nc4)cc23)cc1OC +O=C(O)C1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(-c2ncccn2)cc1 +Cc1ccc(C2CC2COc2nc(C)ncc2-c2ccc(=O)n(CCC#N)c2)nc1 +CCCCCC1(CCCCC)NC(c2nc(-c3ccccc3)c[nH]2)Cc2c1[nH]c1ccc(C)cc21 +CC(C)CC(NC(=O)c1cc(NCc2ccncc2)ccc1-c1ccccc1)C(=O)O +COc1ccc(NC(=O)c2coc(C3C4CCC(O4)C3Cc3ccccc3CCC(=O)O)n2)cc1 +Cc1cccc(-c2noc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)n2)c1 +CCCCc1nc2cc(C=CC(=O)NO)ccc2n1CCN(C)C(C)C +CC(=O)NC(C)c1ccc(OC2CCN(c3cc(OC4CCC4)ncn3)C2)cc1 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+CC(C)c1ccc(CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +Cc1cc(F)ccc1-n1nc(NC(=O)C2CNC(=O)C2)cc1-c1cccc(OC(F)(F)F)c1 +CN(Cc1ccccc1)c1nc2sc3c(c2c(=O)o1)CCN(Cc1ccccc1)C3 +CSc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +CN(C)c1ccc(-c2noc(C(CCCC3CCCCC3)CC(=O)NO)n2)cn1 +Nc1ccc(S(=O)(=O)NCCCCc2c[nH]cn2)cc1 +COCC(=O)N(C)c1ccc(NC(=O)c2nc(-c3ccccc3)oc2C(F)(F)F)cn1 +O=C(O)c1cccc(OCC2CCN(c3ccc(NC(=O)c4ccc5ccccc5n4)cn3)CC2)c1 +Cc1ccc(C2CC2COc2nc(C)ncc2-c2ccn(C(F)F)c(=O)c2)nc1 +COc1cccnc1COc1ccc(-c2nn(CCCF)cc2-c2ccncc2)cc1 +Cc1ccccc1-n1c(-c2cc(C(=O)N(C)Cc3ccccc3-c3cccnc3)c(O)cc2O)n[nH]c1=O +CC(=O)N(C)Cc1ccc2ccc(Cl)c(C3=C(c4cn(C)c5ccccc45)C(=O)NC3=O)c2c1 +COCCCN1C(=O)COc2ccc(OCC3CNCC(=O)N3c3ccc(OCCCOCc4ccccc4OC)cc3)cc21 +O=C(Nc1ccc(Cl)c(Cl)c1)c1ccc2[nH]ccc2c1 +Cn1cnc(-c2cc3nccc(Oc4ccc(N5CC=Cc6c(cnn6-c6ccccc6)C5=O)cc4F)c3s2)c1 +Cc1ncc(-c2ccnc(Nc3ccc(S(=O)(=O)CCCN(C)C)cc3)n2)n1C(C)C +COC(=O)NCc1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCOc1ccc2cc(-c3nn(C(C)C(C)(C)CO)c(N)c3C(N)=O)cnc2c1 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+CN1C2CCCC1CC(N1CCc3cn(C)c4cccc(c34)C1=O)C2 +O=c1[nH]c(=O)n(CCn2ccc3cccnc32)nc1O +COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(C3CC(OC)OC3OC)CC12C +c1ccc2sc(-c3ccc(OCCCCCCNc4c5c(nc6ccccc46)CCCC5)cc3)nc2c1 +CCN(c1nc2ccc(NC(=O)CCc3ccc(C(F)(F)F)cc3)cc2[nH]1)C1CCCCC1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1nc(-c2ccc(OC(F)(F)F)cc2)no1 +Cc1ccccc1-c1c(C(=O)O)n(CCCOc2cccc3ccccc23)c2ccccc12 +CC1=C(C(=O)OC(C)C)C(c2ccsc2)n2c(nc3ccccc32)N1 +CCC(=CC(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)N)c1 +N#Cc1ccc(Cn2cncc2CNC2Cc3ccccc3CN(c3cccc([N+](=O)[O-])c3)C2=O)cc1 +CC(C)C(NC(=O)C(CC(=O)O)NC(=O)CC1CCCN1C(=O)C=Cc1ccc(NC(=N)N)cc1)C(=O)O +Cc1ccc(C2=NC(=O)C(=Cc3ccccc3)S2)cc1 +CC(C)(CN)CNC(=O)C1C(C(=O)Nc2ncc(Br)s2)C2C=CC1C21CC1 +COc1ccc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)cc1 +CC(=O)c1ccc(OCc2ccccc2)c(C=CCc2ccccc2C=CC(=O)O)c1 +COc1ccc2sc3c(c2c1)N(Cc1cccc(Cl)c1)CCNC3=O +CSc1ccc(Oc2ccc(C(=O)N3CCN(C(C)C)CC3)cn2)cc1 +Cc1c2c(nn1Cc1ccccc1)N(O)C(=O)C(N)C2 +CC(C)(C)CC1NC(C(=O)Nc2ccc(C(N)=O)cc2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12 +CN(C)CCN(C)C(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C +O=C(Nc1cc(Oc2cccnc2)ccn1)c1cccc(Cl)c1 +CSc1ccc(C=C(C(=O)NCc2ccc(C(=O)NO)cc2)c2cccnc2)cc1 +COc1cc(NC(=O)NC(C)Cc2ccc(F)cc2)ccc1-c1ccnc(C)c1 +Cc1ccc2cc(-c3cn4nc(C(F)(F)Cl)sc4n3)oc2c1 +CCC(c1ccccc1)c1c(O)c2c(oc1=O)C(C)CCCCCC2 +CNC(=O)C=C(c1ccc(C)cc1)c1ccc2nc(NCC(=O)NC)c(-c3ccc(F)cc3)n2n1 +Cn1c(-c2ccc(O)cc2)cc(C(F)(F)F)c1C#N +CCN(CC)CCCCc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +CC(C)(NC(=O)c1cc2[nH]c3ccccc3c(=O)c2cc1F)c1ccccn1 +Cc1nn(Cc2ccccc2)c(=O)c2ncn3nc(-c4ccccc4)cc3c12 +O=C(O)CC(c1ccccc1Cl)n1ccc2cc(OCCc3ccc4c(n3)NCCC4)ccc21 +O=C(NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1)c1ccc(-c2cccnc2)cc1 +Nc1sc(-c2cncnc2)cc1C(=O)c1ccc(Cl)cc1 +CCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc2ccc(F)cc21 +COc1ccc2c(c1)NC1(CCN(C(=O)c3ccc(N(C)C)c(OC)c3)CC1)c1cccn1-2 +CC1CC2C(CCC3(S(=O)(=O)c4ccc(C(F)(F)F)cc4)c4c(F)ccc(F)c4OCC23)NS1(=O)=O +COc1cc(Oc2c(C)cc(C#N)cc2C)cc(NC2CCN(Cc3ccc(C(N)=O)cc3)CC2)n1 +COC(=O)c1cccc(CNC(=O)c2ccc(-c3cn[nH]c3)c(C)c2)c1 +CC(=O)c1cc(C(=O)N2CCC2)cc2c1-c1ccccc1C2(O)C(F)(F)F +CC(C)=CCCC1(C)C=CC(OC(=O)C=C(C)C)C(C)(O)C=CC(O)C(C=O)=CC1 +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)c3cccc(F)c3)ncc2c1 +Cc1nc(C(C)(C)NC(=O)c2ccc(N3CCCC3)c(OCC3CC3)n2)no1 +COc1ccc(-c2nc(CN3C(=O)CC4(C3=O)C(=O)N(CC(=O)O)c3ccc(Cl)cc34)no2)cc1 +CCC(COC)n1c(=O)c(C)nc2c(-c3ccc(Cl)cc3Cl)ccnc21 +CC1(C)CC1Cn1ncc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)c1=O +O=C(NC1CCCCN(CCc2cccc3ccccc23)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +Cc1cc(-c2ccccc2)cc(C)[n+]1CC(=O)NCCC(=O)Nc1nnc(S(N)(=O)=O)s1 +CN(CCO)c1ccc(-c2csc(NC(=O)CCCCCCC(=O)NO)n2)cc1N +O=C(NC1CCC2CN(Cc3cccc(C(F)(F)F)c3)CC21)C(C1CCCCC1)C1CCCCC1 +O=C(O)CCC(=O)NC1c2ccccc2-c2nc(O)c3nc(C(=O)O)cn3c21 +CN(c1ncnc2[nH]ccc12)C1CC(NS(=O)(=O)CC(F)(F)F)C1 +COCCN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(C)(C)CO +CC(C)c1cccc(C(C)C)c1OC(=O)NC(=O)SCCc1ccccc1 +Cc1ccc(-c2oc3cc(O)c(C(=O)O)cc3c2-c2cn(CCCC(=O)NCc3ccccc3)nn2)cc1 +CCc1nc(N)nc(N)c1-c1ccc(Cl)c(N=NN(CCCO)Cc2ccccc2)c1 +CC(C=CC1(c2cc3c(cc2C)C(C)(C)CCC3(C)C)CC1)=CC(=O)O +Oc1nc2c(c3nc(-c4ccccc4F)nn13)CN(Cc1cccnc1)CC2 +CCc1nc(-c2ccccc2)cc(-c2ccc(F)cc2)c1C=CC1CC(O)CC(=O)O1 +CN(C)CCC(c1ccccc1)n1cc(NC(=O)c2n[nH]c3c2CCC(C)(C)C3)cn1 +C=C(Br)C(=O)Nc1cccc(C=C2CCCCCC(=Cc3cccc(NC(=O)C(=C)Br)c3)C2=O)c1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC(O)C(C)(N)CC1 +CNc1n[nH]c2cc(NC(=O)NC(c3ccccc3)C3CCCO3)ncc12 +COc1ccc(Cn2c(CCc3ccccc3)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)c2ccc(Cl)nc2)cc1 +Cc1cc2ccccc2nc1N1CCN(CCCCc2nc3c(c(=O)n2N)CCCC3)CC1 +CNC(=O)c1cc(Oc2ccc3nc(Nc4cccc(C(C)(C)C)c4)ncc3c2)ccn1 +O=C(NCC1CCCO1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +O=C(NC1CCC(CN2C(=O)Cc3cc(Cl)ccc32)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)ccc2N2CC(O)C(O)C2)cn1 +COCCCn1c(=O)nc(-c2ccc(N3CCN(C)CC3)nc2)c2oc3ccc(-c4cnn(C)c4)cc3c21 +Nc1c(C(=O)NCc2ccco2)c2nc3ccccc3nc2n1CCN1CCCCC1 +CC1CCCN1CCCOc1ccc(C(=O)CN2CCN(C(=O)c3cc4ccccc4s3)CC2)cc1 +O=C1N(Cc2cccc(Cl)c2)c2cscc2S(=O)(=O)N1Cc1ccccc1 +Nc1cc(Oc2ccccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)ncn1 +COc1cccc(C2=C(c3cn(C)c4ccc(Cl)cc34)C(=O)NC2=O)c1 +CCCCCC(=NO)c1ccc(OCCCc2c[nH]cn2)cc1 +CCCCc1nc(SC(F)(F)F)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 +N=C(N)c1ccc2[nH]cc(C(Cc3ccccc3)C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)c2c1 +CCC(=C(c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1 +CC(C)C1(N2CCN(C(=O)C(Cc3ccc(Cl)cc3)NC(=O)CC3NCc4ccccc43)CC2)CCN(C)CC1 +Cc1cccc2c1CCCC2N1CCC2(CC1)C(=O)NCN2c1ccccc1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccsc2)c1 +Cc1cc2nnc(SCc3cn4ccccc4n3)n2c2ccccc12 +COc1cccc2c1-c1ccc(NCc3ccccc3)cc1C(c1ccccc1)O2 +CCC1CC(O)=C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)C(=O)N1Cc1ccc(F)cc1 +Cc1nc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cc(Cl)cc(C#N)c1 +N#Cc1c2n(c3c(N4CCN(CCc5ccccc5)CC4)nc(-c4ccccc4)nc13)CCCC2 +O=C(NC(C(=O)N1CC(F)C2OCC(=O)C21)C1CCCCC1)c1cccc(-n2cnnn2)c1 +O=C(Nc1ccc(Cl)cc1)N1CCC(Cc2c[nH]cn2)CC1 +CCCC1N(CC2CCCCC2)C(=O)OC12CCN(C1CCN(C(=O)c3c(C)cccc3C)CC1)CC2 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+FC(F)(F)c1cccc(Nc2nc3c(-c4nnc[nH]4)cccc3c3sccc23)c1 +O=C(NC1COCCC1NCC1CC1)c1ccc(C(F)(F)F)cc1C1CC1 +CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3Cc2ccoc2)c2cccc(-c3nn[nH]n3)c2)cc1 +CSCCC(NC(=O)c1ccc(C=Cc2cnccn2)cc1-c1ccccc1C)C(=O)O +CCCCCCCCCCC(O)C1CCC(C2CCC(C(O)CC)O2)O1 +CCCCCCNC(=O)NCCc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +CC(C)CCC(c1ccc(C(F)(F)F)nc1)N1CCC(CC(=O)O)CC1c1ccc(C(F)(F)F)cc1 +Cc1cccc(CN2CCCC(C(=O)N(Cc3cc(Cl)c4c(c3)OCCCO4)CC(C)C)C2)c1 +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(CCc3ccco3)CC2)cc1 +COC1CCN(c2nccc(Nc3cc4c(cn3)nc(C)n4C(C)C)n2)CC1 +CC(C)(O)C(F)CNC(=O)c1cnc(N2CCc3cc(C#N)cnc32)cc1NC1COC1 +CCc1nc2c(C)cc(CC(C)C)nc2n1C1CCc2cc(-c3ccccc3C(=O)O)ccc21 +CC(CC(=O)O)CC(=O)N1CCC2(CC1)CCN(c1ccc(C(=N)N)cc1)C2=O +NC(c1cccc(Cl)c1)C1CCN1C(c1cccc(F)c1)c1cccc(F)c1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2F)n(-c2cc3ccccc3cc2S(C)(=O)=O)n1 +Cn1cc(C2=C(c3c4n(c5ccccc35)CCCCC4)C(=O)NC2=O)c2ccccc21 +CC(C)c1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNCC21 +Cn1c(CN2CC3C(COc4cccc(Cl)c4)C3C2)nc2cnccc21 +O=C(Cc1ccccc1)Nc1cc(-c2c(-c3ccc(F)cc3)nc3n2CCS3)ccn1 +O=C(Nc1ncc(Br)s1)C1C(C(=O)NC2CCCNC2)C2CCC1C21CC1 +Cc1cc(C)n2nc(CCc3nc(-c4cccs4)cn3C)nc2n1 +c1ccc(CCCN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +COc1cc(N2CCN(CCNCC(=O)N3CCCC3C#N)C2=O)cc(OC)c1OC +CCC(CC)OC1C=C(C(=O)NS(=O)(=O)c2ccccc2)CC(N)C1NC(C)=O +COc1cc(Cc2c(-c3ccc(CCN4CCCC4)cc3)sc3cc(O)ccc23)ccc1CN1CCCC1 +COc1ccc(COc2ccc(Cn3c(N)nc4cc(N5CCN(C)CC5=O)ccc43)cc2OC)cn1 +COc1cc2c(N)nc(N3CCN(C(=O)c4cc5ccccc5[nH]4)CC3)nc2c(F)c1OC +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(Cl)c2ccccc12 +O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1)C(=O)c1ccccc12 +N=c1n(CC(=O)c2ccc(Cl)cc2)c2cccc(Cl)c2n1CCCN(C(=O)c1cccc2cccnc12)C1CC1 +CCc1cc2c(N3CCN(C(=O)CCOc4ccccc4)CC3)nc(NC(=O)NCCC(=O)O)nc2s1 +COC(C)c1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCOC(=O)C(=O)CC(=O)C=Cc1cccn1Cc1ccccc1OC +Cc1cc(NC(=O)CS(=O)(=O)c2cn(Cc3ccc(-c4cnn(C)c4)nc3)c3cc(F)cc(F)c23)no1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCCCCCCCCCOc1ccc(CN3CCCCC3)cc1)C2 +O=C(NCCCCCCS)c1cc(-c2ccccn2)n[nH]1 +O=C(C=CC(=O)N(Cc1ccccc1)c1ccc(I)cc1)N(Cc1ccccc1)c1ccc(I)cc1 +CC1(C)Cc2nc(C3CCOCC3)c3c(c2C(O)C1)C1(CCCC1)OC3c1ccc(C(F)(F)F)cc1 +CN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +CCCc1c(OCCCCCCc2cccc(OCCCCCC(=O)O)c2CCC(=O)O)ccc2c1CCCC2=O +COc1ccc(Cl)cc1C=C1CNC(=O)CN(S(=O)(=O)c2cc(F)c(Cl)cc2OC)C1=O +CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(Cc1ccccc1)NC(=O)OC12CCOC1OCC2 +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(C(=O)N2CCCC2)CN1 +COc1ccc(C(=O)C2CCN(C3CCN(Cc4nc5c(c(=O)[nH]4)COCC5)C3=O)CC2)cc1 +Cc1cccc(CCC(C(C)O)n2cnc3c(N)ncnc32)c1 +O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CN(C2CCC(CNC(=O)C(F)(F)F)CC2)C1 +CC(C)C(O)CN1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +CS(=O)(=O)c1ccc(C(=O)NC2CCC(CCN3CCC(c4cccc5c4CCO5)CC3)CC2)cc1 +CCCCCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(CCCCCO)cc(-c3ccccc3)n2)CC1 +CC12CCC3c4cc(Br)c(O)cc4CCC3C1CCC2=O +CCCCC(NC)C(=O)NC1CCC2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC21 +O=C(CNC(=O)c1ccc(F)cc1)NC(c1ccccc1)c1ccc(Cl)cc1 +CN(C)CC(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)N(O)C=O 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+CC1CN(c2scnc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cc1n[nH]c2ccccc12 +CC1(F)C(O)C(CO)OC1n1ccc(=O)[nH]c1=O +CCCCn1cc(C(C)(C)C)ccc1=NC(=O)c1cc(C(F)(F)F)ccc1ONC(C)(C)C +O=S(=O)(c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)c(Cl)c2)=N1 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1ccc(C)cc1)O2)C(C)=CC(C)(C)N3 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1ccccn1 +COc1cc(F)ccc1N1CCN(CCCNc2c(C(=O)N(C)C)cnc3c(C(N)=O)cccc23)CC1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCCO)c2)[nH]1 +OC(c1ccccn1)C1(c2cccc(OC(F)(F)F)c2)CCC1 +CC(C)NC(=O)NC1CC2(C)OC1(C)C1C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C12 +O=C(NC1CCC(Oc2ccnc3c(Br)cccc23)CC1)c1ccc(C(F)(F)F)c(F)c1 +CC1COCCN1c1cc(C2(S(C)(=O)=O)CCOCC2)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 +CCc1cc2c(=O)n(N)c(SCCCN3CCN(c4ccccc4[N+](=O)[O-])CC3)nc2s1 +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccc(F)cc2)c2cccs2)CC1 +CC(C)(C)OC(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccc(OCc3ccccc3)cc21 +COc1cc(C=C2SC(=O)N(Cc3ccccc3)C2=O)ccc1OCc1ccc(C(=O)O)cc1 +COc1ccc2[nH]nc(C(=O)NCC3CCN(Cc4ccc(C(=O)O)o4)CC3)c2c1 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+CC(=O)N1CCc2ccc(N(C(=O)C=Cc3ccccc3)C3CCN(CCC4CCCC4)CC3)cc21 +O=C1C(Sc2nnc[nH]2)=CC(=NS(=O)(=O)c2cccs2)c2ccccc21 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1cc(F)c(OCC(F)(F)F)cc1F +CCCCc1cc2c(=O)cc(C)[nH]c2cc1OCCOc1ccccc1 +CCC(NC(Cc1ccccc1)C(=O)Nc1cc(-c2ccncc2)c[nH]c1=O)c1ccccn1 +O=C(CCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1)NC1CCCCC1 +O=C1CC(COc2nc(-c3ccc4c(c3)OCO4)cc3ncccc23)CN1 +CN(C)S(=O)(=O)c1ccc2oc(NC(Cc3ccc(F)cc3)c3ccccn3)nc2c1 +COc1ccc(CN2CC3CN(C(=O)CC(N)Cc4cc(F)c(F)cc4F)CCN3C2=O)cc1 +CCc1ccc(-c2ccc(C(=O)NCC(=O)NC3CNCc4ccccc43)cc2)cc1 +CC(C)=CN1Cc2c(F)ccc3[nH]c(=S)n(c23)CC1C +N#Cc1cc(Cl)cc(Oc2cc(F)c(Cl)c(OCc3n[nH]c4ncccc34)c2)c1 +O=C(OC1CC2COCC(C1)N2)c1cn(-c2nccs2)c2ccccc12 +CC(=O)OC1CCC2(C)C(=CCC3C2CCC2(C)C(C(=O)ON=C(C)N)CCC32)C1 +CNC(C)C(=O)NC1C(=O)N(Cc2c(C3CC3)cnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)C1C +CCSC(=S)SCC(=O)c1ccc(-c2ccc(CNc3cnc4ccccc4c3)cn2)s1 +COCCN(c1c(OC)nn2c(-c3c(OC)cc(COC)cc3OC)csc12)C1CCCCC1 +c1cnc2[nH]cc(-c3ccnc(NC4CCCCC4)c3)c2c1 +O=C(CCCc1ccccc1)Nc1nc2ccsc2c(=O)s1 +NC1=NC(c2cccc(Oc3ccccc3)c2)N(c2cccc(Cl)c2)C(N)=N1 +COc1cccc2c1ccc1nc3ccc(O)c(C(=O)NCCN(C)C)c3nc12 +COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc(C(F)(F)F)c(Oc2cccc(C)c2C#N)n1 +CSC(=O)c1ccc(-c2cnc(C(=O)CCCCCCc3ccccc3)o2)nc1 +FC(F)(F)c1cccc(-c2noc(-c3cc(-c4ccccc4)c(C(F)(F)F)s3)n2)c1 +Oc1nc(-c2ccccc2)cn1C1CCN(Cc2ccccc2)CC1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4c(F)cccc4Cl)ncc23)ccn1 +CCc1ccc(-c2cc(O)c3c(c2)OC(C)(C)C2CC=C(C)CC32)cc1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3cc4ccsc4s3)CC2)nc1 +CCOc1ccc(S(=O)(=O)Nc2ccccc2COC)cc1N1CCNCC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CC(C)O)ncc3Cl)C2)cc1 +O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCNC2)c1O)Nc1cccc2c1OC(F)(F)O2 +O=C1NC(=O)c2ccc(Nc3ccc4c(c3)OCO4)cc2C1=CNc1ccc(CN2CCCCC2)cc1 +CC(c1ccc(-c2ccc(=O)[nH]c2)cc1)N1CCC(CC(C)(C)C#N)(c2ccc(F)cc2)OC1=O +CCCCCCCCOc1ccc(-c2noc(C3CCCN3C(=N)N)n2)cc1C(F)(F)F +COc1cc(F)ccc1-c1ccc(C(CC(=O)O)NC(=O)C2(C)CCCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)cc1 +Cc1cc(C)c(Nc2nc(Nc3ccc(C#N)cc3)ncc2Br)c(C)c1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)Nc1cnn(C2CCOCC2)c1 +COc1cccc(-c2[nH]c3ccc(C)cc3c2CCC(=O)N2CCN(c3ccccc3OC)CC2)c1 +Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc(C(=N)NO[Si](C)(C)C(C)(C)C)s1 +COC(=O)c1cccc(-n2c(=O)n(Cc3ccccc3)c(=O)c3ccccc32)c1 +COc1cc(Cl)ccc1N1C(=O)COc2cc(S(=O)(=O)Nc3nccs3)ccc21 +COc1cc(-c2ccc3ncnc(Nc4ccc(F)c(O)c4F)c3c2)ccc1O +O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2Br)cc1)c1ccncc1F +CCCCC(NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CN1CCN(c2cncc(-c3c[nH]c4ccc(-c5nnc(N)s5)cc34)n2)CC1=O +CCNC(=O)c1cc(NC(C)(C)C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)ccc1Cl +COc1cc(OCc2cccc(OCc3ccccc3)c2)c2cc(-c3cn4nc(Br)sc4n3)oc2c1 +c1ccc2c(c1)ccn2CCCCN1CCN(C2CCCCC2)CC1 +COC(=O)CSc1nnc(Cc2c(NCCC(=O)O)sc3c2CCCC3)n1NC(=O)c1ccccc1 +Cc1occc1-c1ccc(CC(C#N)NC(=O)C2NC3CCC2C3)c(F)c1 +NC(CC(=O)N1CCCC1CN(C1CC1)S(=O)(=O)C(F)(F)F)Cc1cc(F)c(F)cc1F +CCOC(=O)c1ccc(CCCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 +CN1c2ccc(-c3cnc(N)c(F)c3N3CCC4(CC3)CNC(=O)O4)cc2CS1(=O)=O +O=C(Nc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccccc1)OCc1ccccc1 +O=C(O)CC1CCc2cc(OCCCOc3ccc(-n4cncn4)cc3)ccc21 +CNc1nc(NC(=O)c2cccc(I)c2)c2ncn(C3OCC(O)C3O)c2n1 +Nc1nc(OCCC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(=NOCC(N)=O)C5)cn3)n2)s1 +Cc1noc(-c2cnc(C3=CCN(C(=O)Nc4ccc(C(F)(F)F)cc4)CC3)c(Cl)c2)n1 +COc1ccc(C2=Nc3c(C(C)(C)C)nn(CCO)c3C(=O)NC2)cc1-c1cnn(C)c1 +CC(C)NC(=O)Oc1cc(-c2ccnc3c(C(=O)c4cccs4)cnn23)ccc1F +CC(CCc1ccc(-c2ccc(N3CCN(S(C)(=O)=O)CC3)cc2)cc1)(C(=O)NO)S(C)(=O)=O +NC(Cc1cc2ccccc2[nH]1)C(=O)N1Cc2ccccc2CC1C(=O)O +COC(=O)CCCC(=O)Oc1ccc2c(c1)c1cc3c(C(=O)NCCN(C)C)nccc3c(C)c1n2C +c1cncc(Cn2ncc3cc(Nc4ncnn5ccc(COCC6CNCCO6)c45)ccc32)c1 +O=C(NO)c1cnc(N2CC3CN(Cc4cc(Cl)cc(Cl)c4)CC3C2)nc1 +CN1Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4(N)CCOCC4)cc3)cc2C1=O +COc1ccc(Nc2nc3ccc(N4CCN(C(=O)N(C)C)CC4)cn3c2-c2nc(C)nc(N)n2)cn1 +O=C(NCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3CO)n[nH]2)c1 +CCOc1ccc(CC(NC(=O)c2ccccn2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)c(Cl)c2)cc1 +CC1CNC(C2CC2)C(=O)N(C)C(C)C(=O)NC(Cc2ccc(F)cc2)C(=O)NCCCc2ccccc2O1 +CN1c2cc3c(cc2N=C(c2ccc(C(=O)O)cc2)c2ccc4ccccc4c21)C(C)(C)CCC3(C)C +CCCCCCCCC=CCCCCCCCC(=O)NCCC(=O)P(=O)(O)O +Cc1c(-c2nnc(C3(c4ccc(Cl)cc4)CC3)s2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +CC(C)(C)OC(=O)CC1CC(c2ccc(O)c(F)c2)=NO1 +CC(C)(C#N)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +Cc1n[nH]c(=O)c2c1c1cc(Br)ccc1n2Cc1cccc(C#N)c1 +CCN(C(=O)c1ccc(CNc2nc(NCc3ccccc3)nc(N3CCc4ccccc4C3)n2)cc1)c1cccc(C)c1 +COCC1CCCN1C(=O)CC(C)(C)C(N)C(=O)N1CCCC1C#N +CCn1cc(-c2ccccc2)nc1CCc1nc2cc(C)cc(C)n2n1 +Cn1c(C#N)ccc1-c1ccc(C(=O)c2cccs2)cc1 +CCCc1cc2c(=O)c(-c3ccccn3)coc2cc1OC +Cc1cc(N2CCN(S(C)(=O)=O)C(CC(=O)NCc3ccc4c(c3)OCO4)C2)nc(-n2ccnc2)n1 +O=C(Nc1nc2ccccc2s1)c1ccc(-c2ncc(CC(O)CO)cc2F)cc1 +N#Cc1cnc2c(Nc3ccc(F)c(C4(CF)CC(C(F)(F)F)OC(N)=N4)c3)ncc(F)c2c1 +COc1c(COc2ccc(NS(C)(=O)=O)cc2)cc(N2CCC(=O)NC2=O)cc1C(C)(C)C +CCN(CC)Cc1cc2c(N)nc(-c3ccco3)nc2s1 +CC#CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CC(=O)c1ccccc1-c1ccccc1)c(=O)n2C +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2cc(CO)ccc2c1 +O=[N+]([O-])c1cnc(NC2CCC(O)CC2)nc1Nc1ccccc1 +Clc1ncc(C2CC3CCC2N3)cc1-c1cccc(Br)c1 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+COc1ccc(-c2nc(SC)nc(NCCCCNc3ccnc4cc(Cl)ccc34)c2C#N)cc1OC +Cc1cccc(Br)c1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O +CCC(OC)(c1cccc(OCc2ccc3c(-c4ccccc4)c4c(cc3c2)C(=O)OC4)c1)c1nccs1 +Brc1cnc(NC2CCc3ccccc32)nc1Nc1cc(C2CC2)[nH]n1 +CC(c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2F)OC1=O +Cc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4Br)CC3)n2)ccc1F +O=C(Nc1ccc(-c2nc3cc(NC(=O)C4CCC4)ccc3[nH]2)cc1)c1ccccc1Cl +CC(C)(C)NC(=O)C1CN(Cc2ccccc2S)CCN1CC(O)CC(Cc1ccccc1)C(=O)NC1c2ccccc2CC1O +CN(C)c1nc2ccc(C(O)(c3ccncc3)c3cncn3C)cc2c(Cl)c1-c1ccccc1 +Cc1ccc(C(=O)NC2CC2)cc1Nc1nnc(C)c2c1cnn2-c1ccc(F)cc1 +COc1ccc(C(F)(F)F)cc1N1CCOc2cc(S(=O)(=O)Nc3nccs3)ccc21 +COc1cc(Cl)ccc1-c1ccnc2cc(S(=O)(=O)Nc3nccs3)ccc12 +OC12CCC(c3nnc4c(Oc5ccccc5F)cccn34)(CC1)C2 +CC(Oc1ccc(Cl)cc1)C(=O)Nc1cc(C(F)(F)F)ccc1-n1cncn1 +CC(Cc1ccc(Oc2nonc2S(=O)(=O)c2ccccc2)cc1)NCC(O)c1cc(O)cc(O)c1 +CC(C)S(=O)(=O)c1ccccc1Nc1nc(Nc2cccc(NC(=O)CCCN)c2)ncc1Cl +COc1ccc(NC2=C(c3ccccc3)C(=O)N(C)C2=O)cc1 +CC1CN(c2cccc(NS(=O)(=O)c3ccc4ccccc4c3)c2)CC(C)N1 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+CCCC(CCC)N1CCn2c(=O)n(-c3ccccc3OC)c3nc(C)cc1c32 +CC(C)Oc1ccc(-c2ccccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)cc1 +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)N(CC)CC)c3ccc(OC(F)(F)F)cc3)CC2)c(F)c1 +O=C(O)c1cc(=O)c2ccc(OCCCN3CCC(C(O)(c4ccccc4)c4ccccc4)CC3)cc2o1 +NC(=O)c1cccc2c(NC3CNCC(c4ccccc4)C3)ncnc12 +CCC(CC)(NC(=O)c1cc(OCC2(C)COC2)c(C2CC2)cn1)C(=O)NCC(F)CCl +O=C1CSC(=NNc2nncc3ccccc23)N1c1ccc(Cl)cc1 +COc1cccc(-c2ccc3c(c2)Nc2ccc(CCC(=O)N(C)C)cc2NC3=O)c1 +Nc1cc[n+](Cc2ccc3c(c2)-c2cc(C[n+]4ccc(N)c5ccccc54)ccc2C3)c2ccccc12 +O=C(Nc1nc(-c2ccncc2)cs1)N1CCN(CC2CCCO2)CC1 +Cn1cnc2c(NCCNCCO)nc3sc(-c4ccc(F)cc4)nc3c21 +CC(C)c1ccccc1SC1=C(O)OC(CCCCC(=O)N2CCSCC2)(c2ccccc2)CC1=O +CC(=O)C1=CCC2C3(C)CCC4C(C)(C)CCCC4(C(=O)O)C3CC(=O)C2(C)C1C=O +COc1cnc(-n2cnc(C)n2)c2[nH]cc(C(=O)C(=O)NC3C4CN(C(=O)c5ccccc5)CC43)c12 +O=C(Nc1ccc(OC2CCN(C(=O)C3CCCCC3)CC2)cc1)N1Cc2ccccc2C1 +COC1CC(C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +COc1ccc(-c2cc(-c3ccc(-n4cncn4)cc3)cnc2N)cn1 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+O=C(O)Cc1cn(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccncc1 +CCOC(=O)c1ncn2c1c(CO)c(-c1ccccc1)c1ccccc12 +CN=C(N)NCCCC(NS(=O)(=O)c1cccc2c(N(C)C)cccc12)C(=O)N1CCCCC1 +COc1cccc(N2CCN(C(=O)C3CN(S(=O)(=O)c4ccc(OC)c5ccccc45)c4ccccc43)CC2)c1 +O=c1[nH]c(Cc2ccccc2)nc2c1cnn2C1CCOCC1 +CC(=O)n1c(=O)n(Cc2c(F)cccc2F)c2cc(Cl)ccc21 +CN1CCN(CCCOc2ccc(-n3c(-c4ccccn4)nc4cc(F)ccc43)cc2)CC1 +COc1cc(-c2cc(NC(C)c3cccc(OCC(N)=O)c3)nc(C)n2)ccc1C +CC(C)c1ccccc1Nc1nc(SCc2cccs2)n[nH]1 +COc1ccc2cc(-c3cccc(CBr)c3)cc(CCNC(C)=O)c2c1 +CN(C)C(=O)C(CC1CC1)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 +COC(=O)c1cccc(CN2CC3(CCN(CCc4c[nH]c5ccc(F)cc45)CC3)OC2=O)c1 +CC(C)(C)CCC1(C)CN(C2CCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O +Cc1ccc(NC(=O)CN2C(=O)SC(=Cc3cc(Cl)c(OCC(=O)O)c(Cl)c3)C2=O)cc1 +Nc1nc(C#CC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CCC(CO)Nc1ccc2ncc(-c3cccc(C(=O)O)c3)n2n1 +N#Cc1c2ccccc2cn1CCCNC12CC3CC(CC(C3)C1)C2 +O=C(NC1CCc2c(Cl)cc(Cl)cc21)C1COc2ncccc21 +CNC(=O)C(C)C(C)(C)NC(=O)c1cc(OCC2CC2)c(Cl)cn1 +CCCCOc1ccc(C(CC)NC(=O)Oc2ccccc2F)cc1 +COC1(C#CC(O)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CN2CCC1CC2 +COCCOCc1csc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c1Cl +O=C(O)c1ccc(OC2CCN(C(=O)NCc3ccc(Cl)cc3Cl)CC2)cc1 +CSc1nn(-c2ccccc2)c2cc(NC(=O)C3(F)CCNCC3)ccc12 +CC1(C)C(=O)C(C#N)=CC2(C)C3=CC(=O)C(C#N)=CC3(C#Cc3ncc[nH]3)CCC12 +CC1(C)C(=O)Nc2cc3nccc(Oc4ccc(NC(=O)Nc5ccc(F)c(C(F)(F)F)c5)cc4Cl)c3cc21 +CS(=O)(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1ccc(N2CCCC(N)C2)nc1 +C#CCN(C)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)cc1 +Cc1cc(C(C)(C)C)ccc1Nc1nc2ccc(C#N)cc2[nH]1 +O=C(Nc1cccc2c(S(=O)(=O)c3cccc4ccccc34)n[nH]c12)C1CCNCC1 +CCOc1cc(N=S2(=O)CCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NCC(F)(F)F)c12 +CC1(N2CCOCC2)CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +CC#CC1CN(S(=O)(=O)c2ccc(N)nc2)CCN1c1ccc(S(=N)(=O)C(F)(F)F)cc1 +Clc1ccc(-n2cc(COc3ccnc4ccccc34)nn2)cc1 +Cc1cnc(-c2nnc3n2CC(C)N(Cc2cccc(C(F)(F)F)c2Cl)C3=O)cn1 +CN1CCN(c2ccc(-c3ccc4[nH]c5nccc(N6CCC(Cc7ccccc7)CC6)c5c4c3)cc2)CC1 +CCCCCN1CCCc2cc(Oc3ccc(C(N)=O)cn3)ccc2C1 +O=S(=O)(c1ccc(F)cc1)n1cc(C2=CCCNC2)c2ccccc21 +CCCN(c1nc(-c2ccc(Cl)cc2OC)n(C)n1)C(C(C)C)C(C)C +CC(C)(CO)n1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1 +Cc1nnc(CNC(=O)C(c2nc3ccc(-c4ccc(F)cc4)cc3s2)S(=O)(=O)Cc2ccccc2)o1 +CCC(C)(C)NC(=O)Nc1nc2ccc(C(=O)Nc3c(C)cccc3Cl)cc2s1 +CCOc1ccc2c(c1)OC(N)=C(C#N)C2c1cc(Br)c(OC)c(OC)c1 +CC1(C)OC(=O)N(C2CCC(NC(=O)c3cn4ccccc4n3)CC2)C1c1ccccc1 +Cc1ccc2cc(-c3n[nH]c4ccc(C)cc34)[nH]c2c1 +NC1CCCN(c2cncc(-c3cc4c(-c5ccccc5F)n[nH]c4cn3)n2)C1 +COc1ncc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)cnc2C)cc1N1CCOCC1 +CCOCCC1(Oc2ccc(Oc3ccc(-c4cn[nH]c4)cc3)cc2)C(=O)NC(=O)C(N)C1=O +CC(=O)NC1C(NC(=N)NC(=O)Cn2cc(-c3ccc(F)cc3)nn2)C=C(C(=O)O)OC1C(O)C(O)CO +CCON=Cc1cccc2c1CCC1C2c2cc(O)c(Cl)cc2CCN1C +CC(C)(C)c1cc(NC(=O)C2CCCCN2C(=O)N2CCCCC2)no1 +O=C(Cc1cccc(F)c1)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3cccc(F)c3)s2)s1 +CC(Cc1nc2cc(C=CC(=O)NO)ccc2n1CCCO)c1ccccc1 +O=C(Nc1ccc(Br)cc1)NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCN2CCOCC2)CCCC1 +O=C1NCN(c2ccccc2)C12CCN(C1CCc3ccccc3C1)CC2 +CCC1=C(c2ccc3c(c2)OCO3)C(=O)OC1(O)c1ccc(OC)cc1 +CCOC(=O)Nc1cccc(N2CCN(CCCCNC(=O)c3ccc4ccccc4c3)CC2)c1 +CC(=O)c1c2c(n3cccc(F)c13)C(=O)c1ncccc1C2=O +C[N+]12CCC(OC(=O)Nc3ncsc3-c3ccc(F)cc3)(CC1)CC2 +COc1cc2nc(N3CCC(OCC(C)OC)CC3)nc(N)c2cc1OC +CCOC(=O)CC(=O)Nc1cccnc1C(=O)Nc1nccs1 +O=C(NC1CC=C(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1)C1CCOCC1 +O=S1NC(c2ccc(S(=O)(=O)N(CCCCC(F)(F)F)c3sc4ccccc4c3Cl)cc2)=NO1 +CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(OC)cc1 +COC(=O)C(C)NP(=O)(O)OCC1CCC(n2cnc3c(N)ncnc32)C1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(C#Cc3cnccc3O)CCC2C)c1 +O=C(O)C1CC1c1ccc(NCc2ccc(-c3ccccc3)cc2)cc1 +Cc1nnc(CC23CC(F)(F)C(C)C(C=Cc4ccc(-c5ccccc5Cl)cn4)C2C(C)OC3=O)o1 +N#Cc1cnc2[nH]cc(C(=O)c3cccc(NS(=O)(=O)c4cccc(F)c4)c3F)c2c1 +CCCn1c(=O)n(CC(C)C)c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5)CC4)cc3)cc21 +NS(=O)(=O)Oc1ccc(C(c2ccc(OS(N)(=O)=O)c(Br)c2)n2cncn2)cc1Br +COc1cc(-c2c(COC(=O)NC(C)C)c(COC(=O)NC(C)C)c3n2Cc2ccccc2C3)cc(OC)c1OC +O=C(NO)c1cc2ccc(NS(=O)(=O)c3cccc4ccccc34)cc2s1 +CC(CCc1ccc(O)cc1)NC(=O)Cc1c(-c2ccccc2)[nH]c2c(OCCN3CCCCC3)cccc12 +Cc1cccc(C)c1C(=O)NC(Cc1ccc(NC(=O)c2c(Cl)cccc2Cl)cc1)C(=O)O +COCCOCCN1C(=O)C(c2ccc(Cl)cc2)N(C(C)c2ccc(Cl)cc2N)C(=O)c2cc(I)ccc21 +O=C(O)CCCOc1ccc(-c2cc(Oc3cccc(F)c3)ccc2Cl)cc1 +CC(=O)N1CCN(c2cccc(-c3cc(-c4ccnn4CC(F)(F)F)c4c(N)ncnn34)c2)CC1 +CCc1cc(C(=O)NC(Cc2cccc(Cl)c2)C(=O)NCC#N)n(C)n1 +Nc1nc(Cl)c(C#Cc2cccnc2)c(NC2CC(CO)C(O)C2O)n1 +O=C(c1ccc(F)cc1)N1CC2CCN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1 +COC1CCC2(CC1)Cc1ccc(Br)cc1C21NC(=S)N(C2CCN(C)CC2)C1=O +Cn1ncc2c1CCCN2c1cnc2[nH]cc(C(=O)NC(C)(C)C)c2n1 +COc1cccc2c1CCCC2NC(=O)CC1C(=O)NC=CN1S(=O)(=O)c1ccc(C)cc1 +COc1ccc(OCCCON2C(N)=NC(N)=NC23CCOCC3)cc1 +COc1ncc2c(n1)nc(Nc1c(C)cccc1Cl)c1cncn12 +CCOc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2ccc(OC)cc2)CC1 +CN(C)CCc1cn(-c2ccc(F)cc2)c2cc(Cl)ccc12 +CCOc1ccc(-c2cccn3nc(NC(=O)C4CC4)nc23)cc1 +O=[N+]([O-])c1ccc(-c2cn(Cc3ccccc3)c3c2CNCC3)cc1 +CCCC(NC(=O)c1ncco1)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 +Cc1cc(-c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4n3C)cc2)ccn1 +CC(C)c1ccc2occ(C=C3C(=O)N(c4c(Cl)cccc4Cl)c4ccccc43)c(=O)c2c1 +O=C(O)CN1CCN(c2cc(-c3cnc4ccc(N5CCCC5c5cccc(F)c5)nn34)ccn2)CC1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc(C(F)(F)F)cn3)n[nH]c2C1(C)C +CC(=O)NCCCC1OCC(Oc2ccc(OC3CCCC3)cc2)CO1 +CCNC(=O)c1ccc(-c2cc3nnn(C4CCN(c5ncc(CC)cn5)CC4)c3cn2)c(F)c1 +CC1CCCN(c2ncnc3[nH]cc(-c4cccc(C(=O)O)c4)c23)C1 +NC(CS)C(=O)Nc1ccc(NC(=O)Cc2cccc3ccccc23)c(C(=O)c2ccccc2)c1 +COC(=O)c1ccc(NC(=O)CCN2CCC(Cc3c[nH]cn3)CC2)cc1 +O=C(Cn1ncc2c(=O)oc3ccccc3c21)Nc1ccc(F)cc1 +OC(CNCc1ccccc1)Cn1c2ccc(Br)cc2c2cc(Br)ccc21 +Cc1cc(C)c2cc1C(=O)NCCCNC(=O)CCSc1cc-2nc(N)n1 +Cc1nc(-c2ccccn2)nc(NCC(NC(=O)CCN2CCNCC2)c2ccccc2)c1Cl +COc1cc(CCN2CCC(O)(c3ccc(Cl)cc3)CC2)ccc1OCCSSCCN +Cc1cccc(-n2cnc3cc(C(=O)N4CCCC4)ccc32)c1 +CC(C)c1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1 +Fc1ccc(-n2ncc3c(-n4ccnc4)ccnc32)cc1 +COCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3cc(C)ccc3C(F)(F)F)cc2[nH]1 +CC[N+]1(CC2=CCCCCCC2)CCC(NC(=O)C2c3cc(Br)ccc3Oc3ccc(Br)cc32)CC1 +COc1cc2c(C)[nH]c(=O)c(Cc3ccnc4ccccc34)c2cc1OC +O=C(Cc1cn2cc(Cl)ccc2n1)N1CCC2(CC1)CN(Cc1ccc(-n3nccn3)cc1)C2 +O=C1Nc2c(Br)cccc2C1=C1Nc2ccc(C=NO)cc2C1=O +CCc1ncc(Cc2ccc3nc(C)ccc3c2)c2cc(OC)c(OC)cc12 +O=C1NC(Nc2ccc(O)cc2)=NC1=Cc1ccc2c(c1)OCO2 +CC(C)c1csc(NC(=O)C(CC2CCOCC2)c2ccc(S(=O)(=O)C3CC3)cc2)n1 +CN1CCC(c2cc3c(-c4nc(NCC5CCNCC5)ccc4Cl)ccnc3[nH]2)CC1 +c1coc(C2CNC(=Nc3ccc4c(c3)CCCC4)N2)c1 +CC(NC(CCCCCCCCCN)C(=O)NC(CCCN=C(N)N)C(=O)Nc1ccccc1)C(=O)O +CCCCCCC(=CCCCCCCCC(=O)O)[N+](=O)[O-] +O=C1NC(=S)SC1=Cc1csc(-c2ccccc2C(F)(F)F)n1 +CC(C)COC(=O)N1CC2CC1CN2C(=O)C1(C(C)C)CCC(NC2CCOCC2F)C1 +COc1ncc(-c2ccc(F)c(C)c2)c(N2CCC(c3[nH]cnc3C)CC2)n1 +NCc1c(N)nc(N2CCC2)nc1-c1ccc(Cl)cc1Cl +Cc1cc(S(=O)(=O)N2CC(F)(F)C2)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +CN(C)CC1CCc2cc(-c3ccccc3F)ccc2C1(O)c1cccc(O)c1 +Cc1cccc(N2CCN(CC(O)COc3ccc(C(=O)CCc4ccccc4)cc3)CC2)c1C +COc1ccccc1N1CCCN(CCCCNC(=O)c2ccc(-c3ccccc3)s2)CC1 +CCN(C(=O)c1ccccc1OCc1ccccc1)C1CCCC(N)C1 +O=C(Nc1ccc(C(F)(F)F)cc1)N1C2CCC1CC(S(=O)(=O)c1ccncc1)C2 +CC1(c2cc(NC(=O)c3ncc(F)cc3F)ccc2F)CS(=O)(=O)C2(CCC2)C(=N)N1 +CCCCN1C(=O)C2(CCCC2)CC(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccccc1N1CCN(CCOc2ccc3nc[nH]c3c2)CC1 +COc1c(N2CCOCC2)cccc1N1CCN(Cc2ccc(F)cc2Cl)C(=O)C1=O +CCCc1cc(Cc2cnc(N)nc2N)cc2c1OC(C)C2C +COC1CCC(NC(=O)c2n[nH]cc2NC(=O)c2ccccc2)CC1 +CCC(CN1CCC(CNC(=O)c2ccc3ccccc3c2)NC(CCC2CCCCC2)C1=O)c1ccccc1 +O=C(CCCCCCc1ccccc1)c1nnc(-c2cccs2)s1 +CCCCC(O)c1ccc(NC(=O)N2CCCc3ccc(C=O)nc32)nc1 +Cn1cc(-c2cnc(N3CCOC(Cn4nc(-c5cccc(C#N)c5)ccc4=O)C3)nc2)cn1 +COc1ccc(-c2cccc(C(=O)O)c2)cc1OC1CCCC1 +Cc1cccc(CS(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1 +Cc1cc2c(s1)Nc1ccccc1N=C2N1CCN(C)CC1 +CCOc1ccc(COc2c(OC)cc(C=CC(=O)N3CCN(Cc4ccc(Cl)c(Cl)c4)CC3)cc2OC)cc1 +CC1C2Cc3ccc4c(NCc5ccccc5)ncnc4c3C1(C)CCN2CC1CC1 +CCN(CC)CCCc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +O=C(Nc1n[nH]c2nc(-c3ccc(O)cc3)c(-c3ccccc3)cc12)C1CC1 +N=C(N)c1ccc(CNC(=O)Cn2c(-c3ccccc3)c(Cl)nc(NCCc3ccccc3)c2=O)cc1 +O=C(O)CCC(=O)NC(CC(=O)O)Cc1ccc(-c2cc(Cl)ccc2Cl)cc1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccc2[N+](=O)[O-])c1C +CNS(=O)(=O)N(C)C1CC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +O=C1CN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CCN1Cc1cc2c[nH]ccc-2n1 +CC(O)(C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2)c1cnccn1 +CN1CCN(c2cccc3nc(CN(CC(F)(F)F)C4CCCc5cccnc54)cn23)CC1 +CC(C)NCC(O)COc1ccc(C(C)C)cc1OCC(O)CNC(C)C +CC(C)NC(=O)NC(=O)C1CCCN1C(=O)C(CC1CCCC1)CN(O)C=O +CN(C)Cc1ccc(CSCCNc2cc(N)c([N+](=O)[O-])cc2[N+](=O)[O-])o1 +CCc1ncnc(-c2ccc(C(=O)N3CCC4(CCN(C)CC4)CC3)c(OC)c2)c1C#Cc1ccc(N)nc1 +O=S1(=O)Nc2c(ccc3cccnc23)CN1c1ccccc1 +CC1CN(c2ncc(C#Cc3ccc(F)cc3)cn2)C(=O)OC1(C)C +CCCCCCC1=C(c2ccccc2)C2(Nc3ccc(Cl)cc3)CCCC2C1 +Clc1ccc(-c2c[nH]c(-c3cccnc3)n2)cc1Cl +O=C(Nc1nc2ccc(F)cc2s1)C(Cc1c[nH]cn1)NC(=O)C1OC1C(=O)O +CCC(=O)CCCCCC(NC(=O)C1CCN(C)CC1)c1ncc(-c2cc3ccccc3cn2)[nH]1 +COc1ccc(CNCCCNC(=O)C(C)(C)NS(=O)(=O)c2ccc(Cl)c(COc3cccc4ccc(C)nc34)c2Cl)cc1 +CC(C)CCn1cc2c(nc(NC(=O)NC3CCCCC3)n3nc(-c4ccco4)nc23)n1 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+O=C(NC(CCCn1cc(-c2ccc(Br)cc2)nn1)C(=O)O)OCC1c2ccccc2-c2ccccc21 +CN(C)CCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCCOC2)c(=O)n4C)cn1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(CCN(C)Cc4ccccc4)c4ccccc43)CC2)C(C)C)c1 +Cc1[nH]c2ccc(OS(=O)(=O)C(F)(F)F)cc2c1C1=CCNCC1 +O=C(Nc1cc(-c2ccc(Br)cc2)no1)c1nc(C2CC2)ccc1Nc1cncnc1 +COc1ccc(CNC(=O)N(c2ccc(Br)cc2)C2CCN(C3CCCC3)CC2)cc1 +C=Cc1cccc2c1N(CCCC)Cc1cc(OC(C)=O)c(OC(C)=O)cc1-2 +CN1CCCCC1C(=O)N1CCC(O)(c2ccccc2)C2CCCCC21 +CC(c1ccc(OC(F)F)cc1)N1CCC(CCC(N)=O)(c2ccc(F)cc2)OC1=O +COCCOc1cccc2oc(-c3cn4nc(Br)sc4n3)cc12 +CCC(CC)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)NCC1CC1 +CC(O)C(NC(=O)N1CCN(c2ccc(-c3ccccc3)cc2)CC1)C(=O)NO +CCc1c(-c2nnc(C3(c4ccc(Cl)cc4Cl)CC3)s2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1 +CC(C)(C)c1ccc2c(c1)CCC2NC(=O)Nc1cccc2[nH]ncc12 +O=C(Cc1ccccc1)Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1 +CC(NP(=O)(OCC1OC(n2ccc(N)nc2=O)C(F)(F)C1O)Oc1ccccc1)C(=O)OC1CCCCC1 +CC1CN(CC2CC2)CCN1C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C +O=C(O)c1ccc(CCN2C(=O)CCC2C=CC(O)Cc2cccc(Cl)c2)cc1 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+CN(C)CCN1C(=O)c2c(c3c4cc(O)ccc4[nH]c3c3cc4ccccc4cc23)C1=O +CCC1(N(CCO)C(=O)c2ccccc2CCC(O)Cc2ccc(C)cc2C(=O)N(CCO)C(C)(C)c2ccccc2)CCCC1 +Cc1cc2cc(NC(=NC(=O)c3ccc(C(N)=O)nc3)NC3CCCCN(CC(=O)N4CCCC4)C3=O)ccc2o1 +COc1ccc(Cl)cc1C(=O)NNC(=S)NC(=O)c1cc(-c2ccc(Cl)cc2)nc2ccccc12 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)cc1 +NC(=O)C1CCCN1C(=O)CCC(=O)c1ccc2[nH]c3c4c(c5c(c3c2c1)C(=O)NC5=O)CCC4 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2cc(C3CC3)nc(N3CCC4(COC4)C3)c2n1 +CC(NC(=O)COc1cc(C(F)(F)F)c2c(-c3ccccn3)nn(C)c2n1)c1ccccc1 +N=C(N)SCCCn1c(-c2ccc3ccccc3c2)c(C2=CC(=O)NC2=O)c2ccccc21 +NS(=O)(=O)c1ccc(CNC(=S)NC(=O)c2ccc(Cl)c(Cl)c2)cc1 +N#Cc1cc(Cl)cc(Oc2c(C(F)(F)F)ccn(Cc3n[nH]c(=O)[nH]3)c2=O)c1 +C#Cc1cc2c(s1)-n1c(C)nnc1CN=C2c1ccccc1Cl +CC(C)(C)c1ccc(-n2c(C(=O)O)c(Oc3cccc(C(F)(F)F)c3)c3cccnc32)cc1 +CNC1CCN(C(=O)c2cc3cccc(C)c3[nH]2)C1 +Cc1c(C(=O)NCCN(C)C)cc(-c2ccc(-c3ccccc3)cc2)n1-c1ccc(S(N)(=O)=O)cc1 +CC(=O)N1CCc2c(c(-c3cccc(C(F)(F)F)c3)nn2Cc2ccc(Cl)nc2)C1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2ccc3nsnc3c2)[nH]c1=O +CCc1c(C(=O)c2cccc3ccccc23)n(COCc2ccc([N+](=O)[O-])cc2)c(=O)[nH]c1=O +C=C(COC)C(=O)Nc1cccc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1 +COc1cccc(CNC(=O)c2c[nH]c3nc(-c4cn[nH]c4)ccc23)c1 +O=C1c2cccc(O)c2C(=O)c2c(-c3cc[n+](Cc4ccccc4)cc3)noc21 +Cc1nc(S(C)(=O)=O)ccc1Oc1ncnc(OC2CCN(C(=O)C(F)(F)F)CC2)c1F +Cc1ccccc1-c1cc(C(OCc2ccc(OC(F)(F)F)cc2)c2cncn2C)ccc1C#N +CCCCOC(=O)NS(=O)(=O)c1cc(CC(C)C)ccc1-c1cccc(Cn2ccnc2)c1 +Cc1cc(N2CCC3(CC2)OCCO3)cc2[nH]c(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)nc12 +CCCCCOc1c(OC)ccc2cc(C(=O)NCc3ccccc3)c(O)nc12 +CCCCCCN1C(=O)CNC1=Nc1ccc2cc3ccc(N=C4NCC(=O)N4CCCCCC)cc3nc2c1 +COc1ncc2cc(C(=O)Nc3cc(C(=O)Nc4ccccc4)ccc3Cl)c(=O)[nH]c2n1 +Cc1ncc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 +Cn1cc(-c2ccc3nc(NC(=O)C45CC6CC(C)(CC(C)(C6)C4)C5)cn3n2)c(-c2ccc(F)cc2)n1 +NC(CC(=O)N1CCC(N2CCCCC2)CC1)C(=O)N1Cc2ccccc2C1 +CCOc1ccc(-c2cc(NCC(O)c3ccccc3)ncn2)cc1Cl +CNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(CCO)c3n2)cc1 +N#Cc1cccc(CNC(=O)C2COc3ncccc32)c1Cl +CCCCN(CC)c1nc(C)nc2c1ncn2-c1c(C)cc(C)cc1C +COC(=O)c1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(O)cc3)sc2c1 +COc1cc(C=NNc2cc(N3CCOCC3)nc(N3CCOCC3)n2)cc(OC)c1O +CCc1nc2ccccc2n1C(COC(=O)C1CCN(c2nc3ccccc3n2Cc2ccsc2)CC1)C1CCNCC1 +Cc1nc(Nc2ccc(N3CCOCC3)nn2)cc(-c2c(Nc3cc[nH]n3)nc3cccnn23)n1 +CCCCN(c1sc2ccccc2c1C=O)S(=O)(=O)c1ccc(C(=O)OC)cc1 +CCCc1c(-c2ccccc2)noc1-c1nc(-c2ccc(CN3CC(C(=O)O)C3)cc2)no1 +COc1cccc(OC)c1C(=O)NC1CCCC1Nc1cnc(C(F)(F)F)cn1 +Cc1ccc(F)c(-c2cc(Nc3ccnc4cn(CC(N)=O)nc34)c(C)cn2)c1 +CC(O)CCCn1cc(C(=O)c2cccc3ccccc23)c2ccccc21 +CCc1cc(NC(=O)NCC2CCCN(CCc3ccccc3F)C2)cc(-c2nnnn2C)c1 +COc1ccc(C(=O)N2CC3CN(c4nc5ccccc5s4)CC3C2)c(OC)c1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NC(C)(C)C#N +CCCCOc1ccc(S(=O)(=O)N2CC(=NOCC)CC2C(=O)NO)cc1 +CC(=O)N1CCc2c(c(Nc3ccc(-c4cnn(C)c4)cc3)nn2C2COC2)C1 +O=c1c(CNc2ncnc3cc(F)ccc23)cn(-c2ccccc2)c2cc(Cl)ccc12 +CC(C)C(C)Nc1cc(-c2nc3ccccc3nc2-c2ccc(F)cc2)ccn1 +Cc1csc(C(O)C2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)n1 +O=C(c1cccc(Cc2nnc(O)c3ccccc23)c1)N1CCCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 +COc1cc(Nc2ncc(-c3ccccc3N(C)C(=O)CO)o2)ccc1-c1cnco1 +COc1cc(-c2nc(Nc3ccc(Cl)cc3)c3ccccc3n2)cc(OC)c1OC +CCCCCC1=NN(C(=O)NCC2CCCCC2)CC1c1ccccc1 +NCC(c1ccc(C(F)(F)F)nc1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1 +COc1ccc(S(=O)(=O)c2ccc(F)cc2)c(Cc2c(C)c(CC(=O)O)c3ccncn23)c1 +CCn1nc(-c2cccc(-c3cccc(CC(=O)O)c3)c2)cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O +COc1cc2c(cc1OCCCCCN1CCN(C3=NS(=O)(=O)c4ccccc4N3C(C)C)CC1)N=CC1CCCN1C2=O +COc1cccc2c(CC(C)NCC(O)c3cccc(NS(=O)(=O)c4cccs4)c3)cn(Cc3ccccc3)c12 +CC(CCOCC(O)CNC(C)(C)Cc1ccc2ccccc2c1)c1ccccc1 +Cc1ccc(C=C2CN(C(=O)c3ccc(OCCN4CCCCC4)cc3)CC(=Cc3ccc(C)cc3)C2=O)cc1 +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2nnc(N)s2)c(F)c1 +CC(O)(c1ccc(C(=O)N(C2CC2)C2CCC(CCC(N)=O)(c3ccc(F)cc3)CC2)cc1)C(F)(F)F +COc1cc(-c2ccc(Cl)c(C)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)c(F)cc21 +COc1ccc(-c2ccc3cnc(Nc4ccc(N5CCN(C)CC5)c(Cl)c4)nn23)cn1 +CN1CCN(CCNC(=O)C2NC(CC(C)(C)C)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)CC1 +CC1c2ccccc2C=C(C2=CCN(C)CC2)c2ccccc21 +CC1(C)C=C(n2ccccc2=O)c2cc(C(F)(F)F)ccc2O1 +COCCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1ccc(F)cc1 +COc1cc(C)c(-c2cc3cnc(Nc4ccccc4)nc3n(C)c2=O)c(C)c1 +COc1ccccc1-c1cn2c(-c3ccccc3)c(CN)c(C)nc2n1 +CCNCC(=O)Nc1ccc(-c2nc(=O)n(CCCOC)c3c2oc2ccc(Cl)cc23)cc1 +CC1CN2c3c(cc4c(C(F)F)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +Cc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(=O)O)C3=O)cn2)cc1Cl +CC(C)c1nnc2ccc(-c3[nH]cnc3-c3cc(F)ccc3F)cn12 +O=C(c1nc2cc(O)ccc2[nH]1)N1CCC(Oc2ccc(Cl)cc2)CC1 +COc1ccc(-c2ccc(C(N)=O)c(Cl)c2)cc1OC1CCCC1 +Cc1c(Cc2c(F)cccc2F)nc(N(C)c2ccccc2)[nH]c1=O +COc1cccc(CNC(=O)c2ccc(-c3ccncc3)cc2)c1 +O=C(NCCCc1ccc(Cl)c(Cl)c1)C1=C(O)C(=O)N(Cc2ccccc2)C1 +COc1ccc(Nc2c(-c3ccc(OC)c(OC)c3)c(C)nn2-c2ccccc2C)c(C(=O)O)c1 +CC1CCCN1C1CCN(c2ccc(NC(=O)C3CCCO3)cc2)C1 +Cc1cc(N2CCN(c3ccnc4cc(Cl)ccc34)CC2)nc(Nc2ccc(Br)cc2)n1 +O=C1NCc2c1c1c3ccccc3n3c1c1c2c2ccccc2n1CC(O)C(O)C3 +CN(C(=O)CNC(=O)Cc1ccccc1)C(CN1CCCC1)c1ccccc1 +Cc1c(C(=O)OC(C)(C)C)c[nH]c1C(=O)OCC1CC1 +COc1ccc2nc(NCCCN)c3c4ccccc4[nH]c3c2c1 +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(NCc2nc(C(=O)NCCc3ccccc3F)cs2)n1 +C=CC(=O)N1CCC(n2cc(C#Cc3cc(OC)cc(OC)c3)c3c(N)ncnc32)C1 +O=S(=O)(c1ccccc1)N1CCC2(CC1)COC1(OO2)C2CC3CC(C2)CC1C3 +Cn1cc(-c2cc(OCCC(=O)O)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +COc1ccc(CCNC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)c(OC)c1 +COc1ccc(-n2cnc3cc(NCc4ccc(C)cc4)ccc32)cc1 +O=C(O)C1=CSC2C(=Cc3cn4c(n3)sc3cc(F)ccc34)C(=O)N12 +CN1Cc2c(C3=CC(CO)NCC3)[nH]c3nccc(c23)-c2cc(F)c(F)cc21 +O=C(CC1CCCCC1)NC1CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 +O=C(Nc1ccc(OC(F)F)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O +CCC(CC)(NC(=O)CCc1ccccc1)C(=O)NC(C=O)Cc1ccccc1 +O=S(=O)(c1ccc(-n2cccn2)cc1)N(Cc1ccc(OC(F)(F)F)cc1)c1nc2ccccn2c1Br +NC(=O)c1ccnc(Oc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)n1 +CNC1Cc2cccc3c2n(c(=O)n3CCCCCCCCCCCCOc2ccc3c(c2)NC(=O)CC3)C1 +O=C(CCc1ccccc1Cl)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +O=C(C=Cc1c(F)cccc1Cl)Nc1nc2ccccc2[nH]1 +CN1CCC(NC(=O)c2ccc(Oc3ccc(C#CC4(O)CN5CCC4CC5)cc3)cc2)CC1 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+COC(=O)C1C(c2ccc(C)c(C)c2)CC2CCC1N2C +O=[N+]([O-])c1cc2nc(O)c(O)nc2nc1[N+](=O)[O-] +CC(=O)CN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O +Cc1nnc2n1-c1sc(C#CCn3c(=O)c4cc(Cl)ccc4c4ccc(Cl)cc43)cc1C(c1ccccc1Cl)=NC2 +CNC(=O)C(CCOC)NC(=O)C(OCc1ccccc1)C(O)C(O)C(OCc1ccccc1)C(=O)NC1c2ccccc2CC1O +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(c3cccc(C(N)=O)c3)CC2)ncc1Br +CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC1CCCN2C(=O)N(Cc3ccccc3)C(=S)CC12 +Cc1noc(-c2cc3cc(-c4nc(C(=O)NCc5ccncc5)[nH]c4C)ccc3[nH]2)n1 +COc1ccc(Cn2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)cc1 +CC(CCc1ccc(O)cc1)NC(=O)Cc1c(-c2ccccc2)[nH]c2cc(OCCCN3CCCC3)ccc12 +CC1CN(c2cc(-c3n[nH]c4ccc(-c5ccncc5)cc34)ncn2)CC(C)O1 +Oc1cccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccccc4C(C)C)no3)ccc21 +Cc1cncc(NS(=O)(=O)c2ccccc2C(F)(F)F)c1 +COc1ccc2c(c1)CN(C(=O)C(C)C)N=C2Cc1c(Cl)cncc1Cl +Cc1nc2ccc(S(=O)(=O)Nc3ccc(-c4nc5cccnc5s4)cc3)cc2s1 +O=c1[nH]c(N2CCOCC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(C(=O)NCCCO)c2)n1 +Cc1ccc2c(c1)c(=O)c1c3n2CCN(C(=O)CCl)C3CC1 +CC(C(=O)O)N1C(=O)C(=Cc2ccc(-c3ccc(Cl)c(Cl)c3)o2)SC1=S +O=C(NC(Cc1ccccc1)CN1CCN(c2ncccn2)CC1)C12CC3CC(CC(C3)C1)C2 +CCNC(=O)n1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccc(F)cc3)cc21 +O=C(Nc1nc(-c2ccccc2)c(C(=O)c2ccccc2)s1)c1ccccc1 +COC1(CCO)CCN(c2nccc(Nc3cc4c(cn3)nc(C)n4C(C)C)n2)CC1 +O=C(O)c1csc(C2CCC3C(CC(O)C3C=CCOc3ccccc3)O2)n1 +N#Cc1cnc2ccc(-c3ccc(CN4CCOCC4)cc3)cc2c1NC1CC1c1ccccc1 +N#Cc1ccc(-c2cc(-c3cc4c([nH]3)CCNC4=O)ccn2)cc1 +Cc1cc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5ccc(N6CCN(C)CC6)c(F)c5)nc34)CC2)no1 +CCNC(=O)OCCc1cc(-c2cncc(OCC3CCCN3)c2)on1 +OCC1OC(n2c3ccc(Cl)cc3c3c(-c4ccco4)ncnc32)C(O)C1O +CC(C)C(Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(-c3ccncc3)nc2c1 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3C(=O)OC2CCC2)c1C +COc1ccccc1-c1cccc(N2CCN(CCOCCC(=O)NCc3ccc(F)nc3)CC2)c1 +O=c1n(Cc2ccccc2)c2sc3c(c2c2ncnn12)CCN(CC1CCOCC1)C3 +C(#Cc1ccccn1)C1=CCC(Nc2ccc3ccccc3c2)CC1 +COCCN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc(Cl)cc2)cn1 +CONC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(CCN4CCN(C)CC4)cc3)ncc2c1=O +Cc1ccccc1N1CCC(Oc2nc(-c3ccncn3)cc(=O)n2C)CC1 +CC1(C)COC(c2cccc(OC(=O)NC3CCCC3)c2)=N1 +CCN1CC=C(c2ccccc2)C(C(=O)OCCc2ccccc2)C1 +CCOC(=O)C=C1CC(CC)(CC)CC(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Oc1ccc(C2Nc3ccccc3-c3ccnc4[nH]cc2c34)cc1 +OCCOCCNc1nc(Nc2ccccc2)nc(Nc2ccc(F)cc2)n1 +N=C(N)c1ccc(-c2cc(-c3ccc(C(=N)N)cc3)on2)cc1 +CC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)cc1)CC1CCC(C(=O)O)CC1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Nc2ccccc2)cc1 +NC(CSC(c1ccccc1)(c1ccccc1)c1cccc(Cl)c1)C(=O)O +CC(C)(C)CN(C(=O)CCC(=O)N1CCCC(C(=O)O)C1)c1ccc(Cl)cc1C(O)c1cccc2c1OCCO2 +Cc1ccccc1S(=O)(=O)Nc1ccc2c(c1)CN(C)C(=O)N2 +COc1cc(-c2nc(-c3ccccc3)c(-c3ccc(Br)cc3)[nH]2)cc(OC)c1O +CC(C)CC(NC(=O)Nc1ccc(-c2noc(-c3cccs3)n2)cc1)C(=O)N(C)N(C)C#N +NC(CCNCc1ccccc1OCc1ccccc1)C(=O)N1CCCCC1 +Cc1ccc(C(C(=O)NC(C)C)N2C(=O)C(C3Cc4ccccc4C3)NC(=O)C2CC(C)C)cc1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CCOCC3CO)ns2)n1 +CC=C1CCC2C3CCC4CC(NC(=O)c5ccc(C#N)cc5)CCC4(C)C3CCC12C +Oc1ccc(C(=Nc2ccccc2)c2ccc(O)cc2)cc1 +OCCn1cc(-c2cc3c(-c4cccc(N5CCNCC5)n4)n[nH]c3cn2)cn1 +Cc1cccnc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COc1cc(NC(=O)c2cccc(NC3=NCCCN3)c2)ccc1CC(NC(=O)OC(C)C)C(=O)O +Cc1nccn1-c1ccc(COc2cc(F)cc(C3(C(=O)N(C)C)CCOCC3)c2)cc1 +Cc1cc(CCC(=O)O)cc(C)c1-c1nc2ccc(C(=O)Nc3ccc4ccccc4n3)cc2[nH]1 +O=S(=O)(Nc1cscn1)c1cc(F)c(Oc2ccc(Cl)cc2C2CNC2)cc1F +C[S+]([O-])c1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CCCCC3)c2)[nH]1 +CCc1cn(C2OC(CNC(=O)C3c4cccc(C)c4Oc4c(C)cccc43)C(O)C2F)c(=O)[nH]c1=O +COc1nccnc1CC1=C(CCN(C)C)Cc2ccccc21 +CCCCCC(=O)OCC(CO)OC1OC(COC(=O)CCCCC)C(O)C(O)C1O +Cn1nc(-c2ccc(F)cc2)c(-c2ccc3nc(NC(=O)c4ccnc(F)c4)cn3n2)c1N1CCN(CCCF)CC1 +Cc1cc(NC(=O)C=Cc2ccccc2)c(C(C)C)cc1O +COc1cccc(N(C(=O)CCl)C(C(=O)NCCc2ccccc2)c2cccs2)c1 +CC1C=CC(C)N1C(=O)c1ccc(-c2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)s1 +CC(NC(=O)CNC(=O)Nc1ccc(C(=N)N)cc1)c1ccc(N2CCOCC2)cc1 +CN(C)c1cc[n+](Cc2ccc(C[n+]3ccc(N4CCCC4)cc3)cc2)cc1 +CC(=O)c1ccc(OCc2ccsc2)cc1OC(CCC(=O)O)c1ccccc1C +Cc1noc(C2C(c3ccc(Cl)cc3)CC3CCC2N3C)c1-c1ccc(Cl)cc1 +Cc1cc(C2CCC2)c(-c2nc3c([nH]2)COCC3)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +CC(C)Cn1cnc2c(NCCCCCCC(=O)NO)nc(NCc3ccccc3)nc21 +O=C1Nc2ccc(C(=O)NC(CO)c3ccccc3)cc2C1=Cc1ccn[nH]1 +CS(=O)(=O)N1CCC(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +Cc1ccc(N(CCCCCCC(=O)NO)c2ccccn2)nc1 +CN(C)c1cccc2c(S(=O)(=O)NCCCCCCCNc3ccnc4cc(Cl)ccc34)cccc12 +CCN(CC)CCN1C(=O)C(O)(c2cc3ccccc3cc2Cl)c2c1cc(C(N)=O)cc2C(F)(F)F +CC1CN(c2noc(C(F)F)n2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Cn1cc(NC(=O)c2ccc3ccc(NC4CCCCC4N)nn23)c(C(F)(F)F)n1 +O=C(CCCn1cnc([N+](=O)[O-])n1)Nc1cccc(Cl)c1 +CNc1ncc2ncnc(Nc3cc(C(=O)Nc4cc(CN5CCCC5)cc(C(F)(F)F)c4)ccc3C)c2n1 +CN1C(=O)Cc2cc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4CC5)cc3)ccc21 +NNc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Cc1c(S(=O)(=O)NCCO)cc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)n1CC1CCCCC1 +Cc1ccc(N2CCc3ncnc(NC(C)c4cccc(Cl)c4)c3C2)nc1 +CCc1cc(OC)cc2nc(-c3cccnc3N3CCN(CCN(C)C)CC3)oc(=O)c12 +COc1ccc(CNCCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)cc1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCC4(CC4)C3)n2)cc1OC(F)F +CC(C)(C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 +COc1cccc(CNC(=O)CC2(C)CC3(CCCCC3)OO2)c1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(CCCC(=O)O)cc1)Cc1ccc(Oc2ccccc2)cc1 +CCC1OCC(O)=C2C1=NC1=C(C(=O)COC1)C2c1ccc(F)c(Cl)c1 +COc1cccc(-c2cccc(NC(=O)Nc3cc4ccc(OC5CCN(C)CC5)c(C)c4oc3=O)c2)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(NC4CCCC4)c3Cl)C2)cc1 +O=C(O)C1CN(c2cc3c(cc2F)-c2noc(-c4onc(-c5ccccc5)c4C(F)(F)F)c2CC3)C1 +CC1(Cc2ccccc2)COc2ccc(C(=O)NC3CCCCC3)cc21 +Nc1nc(N)c2nc(CNc3ccc(C(=O)NC(CCC(=O)Nc4cccc(C(=O)O)c4)C(=O)O)cc3)cnc2n1 +CC(=O)N1C2C=C(CN3C4CCC3CC(Nc3ccc5ccc(OC(C)C)cc5n3)C4)CC1CCC2 +COCCN(C)C1CCC(OC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccc(F)cc1 +CCC1(O)CCC(C)(C(=O)Nc2nc3c(OC)ccc(N4CCOCC4)c3s2)CC1 +CC(=O)Oc1c(C)cc(Cl)c2c1C(=O)C=CC2=O +Cc1ccc2c(c1)-c1nc(NCC3CCN(C(=O)C(C)C)CC3)sc1CCO2 +CCN(c1ncccc1NC(C)C)C1CCN(C(=O)c2cc3cc(NS(C)(=O)=O)ccc3[nH]2)CC1 +CC(C)(CNC(=O)c1cnc(N2CCC(CO)CC2)cn1)c1ccccc1 +CC(C)(CNS(=O)(=O)c1ccc2c(Cl)cnc(N=C(N)N)c2c1)C(=O)O +COc1ccc(-c2c(-c3ccccc3)nc3ccccn23)cc1 +CN(C)C1CCc2c(c3cc(Br)ccc3n2S(=O)(=O)c2cc(C(F)(F)F)ccc2Cl)C1 +Cc1c(CCO)sc[n+]1CCOc1ccc(Cc2ccc(OCC[n+]3csc(CCO)c3C)cc2)cc1 +O=C(Nc1ccc(N2CCN(C(=O)OC3CCCC3)CC2)nc1)c1oc(N2CCCCC2)nc1C(F)(F)F +O=C(CN1CCC(O)CC1)OC1CC2(N3CCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2 +COC(=O)C(C)(C)Cn1c(=O)[nH]c(=Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(C)cc2)c1=O +Cc1ccc(F)cc1C(=O)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +COc1ccc(C(O)=CC=Nc2cccc(C)n2)cc1OC +O=C1CSC(c2ccccc2)N1CCNc1ccnc2cc(Cl)ccc12 +CCC(=O)OC1CCN(CCCC(=O)c2ccc(F)cc2)CC1 +COc1cc(-c2oc3ncnc(NCC4CCCO4)c3c2-c2ccccc2)ccc1OCCN1CCCCC1 +COc1ccc(C2(c3ccc(C#N)c(-c4cccnc4)c3)N=C(N)N(C)C2=O)cc1C +CC(C(c1ccc2cc(OCc3ccc(C#N)cc3)ccc2c1)n1ccnc1)N(C)C +COc1ccc(-[n+]2c(-c3ccc(Br)cc3)cn3c2CCc2ccccc2-3)cc1 +NC(=O)c1nc(-c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)nc(N2CCOCC2)n1 +CCS(=O)(=O)c1ccc(-c2ccc(-c3n[nH]c4c3Cc3cc(O)c(OC)cc3-4)cc2)cc1 +CC12CCC3C(CCC4CCCCCC43C)C1CC=C2n1ccnc1 +O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cn[nH]c1 +Cn1c(=O)n(C)c2cc(-c3[nH]c(-c4cccs4)nc3-c3ccccc3F)ccc21 +Nc1cnc(-c2ccc(C3CCC3)c(OCc3cccc(Cl)c3Cl)c2F)cn1 +CC(NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OC2CCOCC2)c1 +CCCCNS(=O)(=O)n1nc(C(=O)NC)c2c1-c1c[nH]nc1CC2 +Cc1noc(-c2c(F)cccc2C(=O)N2C3CCC2C(Nc2cnc(C(F)(F)F)cn2)C3)n1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3scnc3C)cc2)C(=O)C2CCCCC2)c1 +CC1CCCC(n2cnc(CC(CCCN)C(=O)O)c2)C1 +COc1cc(C(=N)N)ccc1-c1cc(-c2ccc(C(=N)N)cc2)on1 +N#Cc1cccc(-c2cc(C(F)(F)F)ccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)c1 +Cc1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)NC(C)(C)C)CC3)c2C)c1 +CC12CC(c3ccoc3)(c3ccoc3)C(c3ccccc31)c1cccc[n+]12 +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1cccc(Oc2cncc(-c3ccc(S(C)(=O)=O)cc3)n2)c1 +O=C(O)CON=CC=C(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +CNc1nc(Nc2cc3c(cc2Cl)C(=O)N(C)C3)ncc1C(F)(F)F +O=C(Nc1cc2ccc(C3(O)CCCCC3)nc2cn1)C1CC1 +Cc1cc(C(=O)Nc2cc(OC(C)C)cc(OC(C)C)c2)cc(C)c1OCCN +COc1ccc(S(=O)(=O)NCC(O)C(Cc2ccccc2)NCc2cc(Cl)ccc2-n2cnnn2)cc1 +CCC(Oc1ccccc1)C(=O)N(Cc1ccccc1)CC1CCCN1 +N=C(N)c1ccc2[nH]c(-c3cc(CC(=O)O)cc(-c4cccc(C(=O)O)c4)c3O)cc2c1 +Nc1ncc(CCCCc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)c(N)n1 +O=C(Cc1c[nH]c2ccc(Br)cc12)NC1CCN(Cc2ccccc2)CC1 +CC(=O)NCCC1=C(C(C)C)Cc2ccc3c(c21)CCO3 +CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc(N4CCCC4)nc3)c2)cc1 +Cc1ncc(-c2nc(C(F)(F)F)cn2-c2ccc(S(N)(=O)=O)cc2)s1 +CCOC(=O)c1ncn2c1CN(C)C(=O)c1cc(OCCF)ccc1-2 +Cc1c(C(=O)NC2CCN(C)CC2)sc2ncnc(Nc3ccc(C#N)cc3OC(CF)CF)c12 +CN1CCN(c2ccc(Nc3cc(-c4c[nH]c5ccccc45)ncn3)cc2)CC1 +COc1cccc(CNC(=O)C=C2c3ccccc3N(C(=O)c3ccc(-n4ccc(C)n4)cc3Cl)CCC2(F)F)n1 +CCN(C1CCN(Cc2cccc(C(=N)N)c2)C1=O)S(=O)(=O)c1ccc2ccc(OC)cc2c1 +NC(COc1cncc(-c2cccc3cnccc23)c1)Cc1c[nH]c2ccccc12 +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3c(Cl)cccc3Cl)c3ccccc32)CC1 +COc1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 +CCOc1n[nH]c2cc(NC(=O)NC(c3ccccc3)C(O)COC)ncc12 +N#CCc1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1 +CC(OCC1(c2ccccc2)CCC2(CN1)NC(=O)NC2=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +N=C(N)NCCCC(NC(=O)C1CCC2CN(C(=O)C(O)Cc3ccccc3)CC(=O)N21)C(=O)c1nccs1 +CCn1c(=O)c2cnc3c(OC)cccc3c2n(C2CCC(C)CC2)c1=O +CCOc1cccc(-n2cc(C(=O)N3CCN(c4ccc5ccccc5c4)CC3)nc2-c2ccc(Cl)cc2)c1 +CC(C)(C)c1ccc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 +CC(Nc1nc(Nc2ccc(S(=O)(CC=O)=NS(=O)(=O)CC[Si](C)(C)C)cc2)ncc1Br)C(C)(C)O +COc1cc(C)c2nc3[nH]nc(C)c3c(N3CCN(C(N)=O)C(C)C3)c2c1 +Nc1nc(Nc2ccccc2)c2c(n1)[nH]c1ccccc12 +Fc1cccc(COc2cncc(-c3ccnc4[nH]c(C5CCNCC5)cc34)n2)c1 +CC(c1ccc(C(F)F)cc1)N1CCC2(CCC(O)CC2)OC1=O +COc1ccc(NC(=O)c2ccc(C)c(N(C)c3ncnc4cnc(N5CCOCC5)nc34)c2)cc1C(F)(F)F +CN(C)CCNc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +Nc1cccc(CN2C(=O)N(Cc3ccc4[nH]nc(N)c4c3)C(CCc3ccccc3)C(O)C2Cc2ccccc2)c1 +O=C1c2ccc(Br)cc2C(=O)c2cc(O)c(O)cc21 +COc1nc(N(C)C)ncc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)cn(C)c1=O)C2=O +COC(=O)c1ccc(Oc2ccc(C(=O)Nc3ccc(C4CNCCO4)cc3)cc2)cc1Cl +CCc1ccc(C(=O)NN(C(=O)c2cc(C)cc(C)c2Cl)C(C)(C)C)cc1 +COc1ncccc1CN1CC(c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C)cc3)n2)C1 +CN1CCC(C(=O)N2CC=C(c3ccc(NC(=O)N4Cc5ccncc5C4)cc3)CC2)C1 +COc1ccc(Cn2c(NCCNC(=N)N)nc(=O)n(Cc3ccc(F)cc3)c2=O)cc1 +NC1CCCC1Oc1cncc(-c2cc3c(cn2)cnn3-c2ccccn2)n1 +CC(=CC(=O)c1ccccc1)NC(Cc1ccc(OCCCOc2ccc(C=Cc3ccc(Cl)cc3)cc2)cc1)C(=O)O +N=C(N)c1ccc2[nH]c(-c3cc(CC(=O)O)cc(-c4cc(CNC(N)=O)ccc4O)c3O)nc2c1 +COc1cccc(CNC(=O)c2nc(-c3cccs3)nc(O)c2O)c1 +O=C(Cc1ccccc1)Nc1ccc(OC2CCN(c3ccc(NC(=O)Cc4ccccc4)nn3)CC2)nn1 +CC1(O)CC(N)(c2ccc(-c3nc4n(c3-c3ccccc3)COc3cnccc3-4)cc2)C1 +Cc1cccc(COc2cc(=O)n3cc(Oc4cccnc4)ccc3n2)n1 +CCCc1nc(-c2ccc(F)cc2)oc1C(=O)NC(C)CN1CCN(c2nccs2)CC1 +CC(C)=CCCC(C)=CCCC(C)=CCNCc1ccncc1 +CCCCC1=NC(CC)(C2CCCCC2)C(=O)N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3cccc(C(=O)O)c3)cc2)cc1)C(=O)O +CSc1sc(C(=N)N)cc1-c1csc(Nc2cccc(Cl)c2C)n1 +COC(=O)CSc1cc(-n2c(=S)n3n(c2=S)CCCC3)c(F)cc1Cl +O=C(CN1CCCCC1)Nc1cc(CNCc2ccc(C(F)(F)F)cc2)cc(Nc2ccnc3cc(Cl)ccc23)c1 +CNC(=O)CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21 +CC1(O)CC(=O)OC(CSc2nc(-c3cccc(Cl)c3)c(-c3cccc(Cl)c3)[nH]2)C1 +COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COc1nc3ccccn3c(=O)c1Cc1ccccc1)C2=O +COC1CCC2(CC1)Cc1ccc(-c3cc(Cl)cc(C#N)c3)cc1C21N=C(C)C(N)=N1 +Cc1cccc(Nc2ncc3ccn(-c4ccccn4)c3n2)c1 +O=C1c2cc([N+](=O)[O-])ccc2-n2c1nc1cccc(Br)c1c2=O +CNC(=O)Nc1ccc2c(c1)C(=O)C(=Cc1cn(C)c3nccc(N4CC5CCC(C4)O5)c13)O2 +CCOc1ccc(-c2cc(-c3cnc(NC(C)C)s3)nc(-c3cnccn3)n2)c(Cl)c1 +CNC(=O)c1ccc(OC2CCC(NC(=O)NC34CC5CC(CC(C5)C3)C4)CC2)cc1 +CC(=O)c1nc([N+](=O)[O-])c(Sc2c(Cl)cncc2Cl)s1 +COc1ccc(C(F)(F)F)cc1NC(=O)Nc1ccc(Oc2cccc(C(=O)Nc3ccc(N4CCOCC4)cc3)c2)cc1 +O=C(Nc1cccc2nonc12)N1CC2(CCN(Cc3cccc(Oc4ccc(Cl)cc4)c3)CC2)C1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)N1CC(=O)C(NC(=O)c2ccc(Oc3ccccc3)cc2)C1 +COc1ccc(C=CC(=O)C(C=CC#N)=C(O)C=Cc2ccc(OC)c(OC)c2)cc1OC +CN(C)CCCCn1ccc2ccc(NC(=N)c3cccs3)cc21 +COc1cc(NCc2cc3ccccc3o2)c2nccc(C)c2c1Oc1cccc(C(F)(F)F)c1 +Cc1cc(N2C(=O)OCC2C(C)O)nc(NC(C)c2cnc(-c3ccc(Cl)cc3)s2)n1 +CC1(C)C(C(=O)O)C1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(Br)cc1F +Cc1ccc(COC(=O)NC(=O)c2cc(-c3ccc(OC(F)(F)F)cc3)cs2)cc1 +CN1c2ccc(-c3cncc(Cl)c3N3CCC4(CC3)C(=O)NN=C4C(F)(F)F)cc2CS1(=O)=O +CCCCSc1nc(NC(C)=O)cc(OCc2ccc(Cl)cc2)n1 +COCCOc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1OCCCCCCC(=O)NO +O=C(C=Cc1ccc(O)c(O)c1)OCCc1cccc(OCCc2cccc(O)c2)c1 +CN(C)C(=N)c1ccc(NC(=O)c2nnnn2-c2ccc3cc(Cl)ccc3c2)c(F)c1 +NC1=NC2(CO1)c1cc(-c3cc(Cl)cnc3F)ccc1OC1(CCC1)C21COC1 +CC(c1cccc(C(F)(F)F)c1)N1CC(c2cccc(C(F)(F)F)c2)N(CC(O)C(F)(F)F)c2ccccc21 +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NCc1ccccc1 +CSc1c(CC(N)=O)c2cc(O)ccc2n1Cc1ccccc1 +CC(C)(C)c1ccc(C(O)c2ccnc(Nc3ccc(C#N)cc3)n2)cc1 +COc1ccc(C(=O)Nc2c(Cl)cccc2Cl)cc1OC1CCCC1 +O=C(O)COc1ccc(Cl)cc1N(C1c2scnc2CCN1C(=O)OCc1ccccc1)S(=O)(=O)C1CC1 +COC(=O)CCC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)CC1CCCCC1 +CCCCN(CC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)nn(CC)c12 +CC(=NNC(N)=S)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +CCCCOc1ccc(S(=O)(=O)N2CC(N3CCCS3(=O)=O)CC2C(=O)NO)cc1 +CC1CCC(NC(=O)c2cc3cccnc3n(CCCO)c2=O)CC1 +CC(=O)N1Cc2c(-c3nc(C4CC4)no3)ncn2-c2ccccc21 +FC(F)(F)CNCc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +O=C(c1nn(C2CCN(CCC3CCOCC3)C2)c2c1CS(=O)(=O)c1c(F)cccc1-2)N1CCOCC1 +CNc1cc(C(=O)O)nc2c(-c3cccc(F)c3O)nc(N3CCOCC3)nc12 +Nc1ncc(C2CNC(=O)C2)cc1-c1ccc(C(=O)NC(CO)c2ccccc2)c(F)c1 +Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc([N+](=O)[O-])cc1 +OC1(c2ccc(Cl)cc2)c2cc3ccccc3cc2C2=NCCN21 +N#Cc1cccc(C(=O)NCCc2nc(-c3ccc(F)cc3)cs2)c1 +CCCCN(c1sc2ccccc2c1Br)S(=O)(=O)N(C)C +CCOC(=O)CCN1c2c(ssc2=O)Sc2ssc(=O)c21 +Cc1nc(-c2ccccn2)nc(NCC(NS(=O)(=O)CCN2CCNCC2)c2ccccc2)c1Cl +COCCNC(=O)c1cnc(Nc2ccc(OC)nc2)c(-c2nc(C)nc(N)n2)c1 +COc1cc2c(cc1OC)-c1n[nH]c(Nc3cccc(Cl)c3)c1C2 +CSc1nnc(C2CC(S)CN2S(=O)(=O)c2ccc3ccccc3c2)n1-c1c(F)c(F)cc(F)c1F +CCN1C(=O)CCC1C(=O)NCc1c(F)ccc(C)c1Cl +Cc1c(F)ccc(C(=O)Nc2cc(C(=O)OC(C)C)ccc2N2CCN(C)CC2)c1Cl +O=C(NCCc1ccc(OCCN2CCCC2)c(Br)c1)c1cccc(Cl)c1 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)Cc1nc2c(C(F)(F)F)cccc2[nH]1 +Cc1cn(C2CCCN(S(=O)(=O)c3ccc(O)c(Oc4ccc(Cl)cc4)c3)C2)c(=O)[nH]c1=O +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1CN1CCOCC1 +COc1ccc(C(=O)CC(=O)C(=O)O)cc1Cc1ccccc1 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+O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(Oc2cnc(OCC(F)(F)C(F)F)c(Cl)c2)cc1F +O=C(O)c1c(O)c(-c2ccc(-c3ccc(O)cc3)cc2)nc2ccccc12 +CCOc1ccccc1N1CCN(CCCC(=O)NCc2nc3ccccc3c(=O)n2-c2ccccc2)CC1 +Nc1ccc(-c2cc(C=C3CN4CCC3CC4)on2)cc1 +CC1(C)CC1C(=O)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O +O=c1n(-c2ccc(F)cc2)ccc2nc(COc3ccccc3)cn12 +Cc1c(Sc2ccc(Cl)cc2)c2ccc(Cl)cc2n1CC(=O)O +CCCCn1cc2c(nc(NC(=O)Cc3ccc4ccccc4c3)n3nc(-c4ccco4)nc23)n1 +CC1c2c([nH]c3ccc(C(F)(F)F)cc23)CC2CCN(CCc3ccccc3)CC21 +O=C(Nc1ccc(-c2ccc(C(=O)C3CCCC3C(=O)O)cc2)cc1)Nc1cccc(F)c1 +Cc1ccc2[nH]c(NC(CC#N)c3cccc(Cl)c3)nc2n1 +NS(=O)(=O)c1ccc(-n2cc(-c3nc4ccccc4[nH]3)c(-c3ccccc3)n2)cc1 +O=C(Cc1ccccc1)Nc1ccc2c(c1)Cc1c-2nc(O)c2nccn12 +CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccc(O)cc1 +CCN(C)C(=O)Oc1cccc2c1CCN2CCC(=O)OC +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OCC(C)(C)C)ccn5)n4)ccc3[nH]2)CC1 +CCn1cc(-c2cc3c(-c4cccc(N5CCOCC5)n4)n[nH]c3cn2)cn1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)c4cccc(F)c4)nc23)N1 +O=C(NCc1ccsc1)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 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+O=[N+]([O-])c1cc(-c2cc3ccccc3[nH]2)ccc1-c1cc2ccc(Br)cc2[nH]1 +CCCCCC(O)C=CC1C(O)CC(=O)N1CC=CCCCC(=O)O +CCc1ncnc(-c2ccc(C(=O)N3CCC(N4CCC(C)CC4)C3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +O=C(O)c1ccc(NC(=O)c2cc3ccccc3nc2Oc2ccc(F)cc2F)cc1 +c1ccc(N2CCNCC2)c(COc2ccccc2C2CC2)c1 +Cn1cc(S(=O)(=O)c2ccc(CNC(=O)c3cc4ccncc4s3)nc2)cn1 +CCCCCCCCC=CCCCCCCCCCC1(O)C(=O)C=CC(O)C1O +CNc1ncc2cc(-c3ccccc3)c(-c3ccc(CN4CCC(c5nnc(-c6ccccn6)[nH]5)CC4)cc3)nc2n1 +COc1cc(C=C2CCCC(=Cc3cccc(Cl)c3)C2=O)cc(OC)c1 +O=C(O)c1ccc2c(c1)C(=CCCN1CCCC1)c1ccccc1CO2 +Cc1cn2cc(CNc3ncnc4ccc(N5CCCC5c5cc(F)ccc5F)nc34)nc2s1 +O=C(NC1CCC2CN(Cc3cccc(OC(F)(F)F)c3)CC21)C(C1CCCCC1)C1CCCCC1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccccc5)cc4=O)cc31)C1CCCCN1CC2 +NC(N)=NN=C1c2ccccc2CC1Sc1nc2ccccc2[nH]1 +CN1CC(Cc2c(F)cccc2F)CC(NC(=O)c2ccc3[nH]nc(-c4ccc5ncsc5c4)c3c2)C1 +CC(C)(C)C(=O)OCC1(CO)CC(=CCCCCCCCCCCCCCCCN=[N+]=[N-])C(=O)O1 +Cn1cc(-c2ccc3nnc(Sc4ccc5ncc(CN6CCOCC6)cc5c4)n3c2)cn1 +NC(=O)c1cnn2ccc(N3CCCC3c3cc(F)cc(OCCN4CCOCC4)c3)nc12 +CNC(=O)c1ccc(Nc2nn(C3CCCCC3C#N)cc2C(N)=O)cc1 +CC1CCCCN1C(=O)Cc1ccc(C=NNC(=O)c2ccc(O)c(C#N)c2)c2ccccc12 +COC(=O)c1cn(-c2ccc(S(N)(=O)=O)cc2)nc1-c1ccc(F)cc1 +[C-]#[N+]c1cc(C2CN3CCN(C(=O)Cc4cnc(-n5cnnn5)nc4)CC3CN2)ccc1F +CN1CCN(c2nccnc2OC2CC(Nc3ncc4ccccc4n3)C2)CC1 +CN(CCCCc1c[nH]cn1)C(=O)CC(c1ccc(Cl)cc1)c1ccccn1 +CC1CCN(CCCOc2ccc(-c3ccc(C(=O)N4CCC(C)CC4)cc3)cc2)CC1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(Cc1ccc(C(=O)Nc3ccccc3)cc1)CC2 +O=[N+]([O-])c1ccc(S(=O)(=O)NCC(c2cccnc2)N2CCc3ccccc32)cc1 +CCCc1ccc2c(c1)[nH]c(=O)c1nc(-c3ccccc3Cl)[nH]c12 +CCOC(=O)c1c(NC(=O)Cc2ccccc2)sc2c1CCN(C(=O)OCC)C2 +CC=CC=C(CC(=O)NO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC +CN1CCN(C2=Nc3cc(OS(C)(=O)=O)ccc3Nc3ccccc32)CC1 +O=C(C=Cc1ccc(C(F)(F)F)cc1)N1CCCC1CN1CCCC1 +COC1(c2ccccn2)CCCN(c2nnc(N3CCC(N4CCCCC4)CC3)s2)C1 +O=C(O)c1ccc(-c2cc(=O)c3ccccc3o2)cc1 +O=S(=O)(NCCCN1CCN(c2noc3ccccc23)CC1)c1cc2ccccc2s1 +C=C(COc1ccc2c3c1OC1C4(OC)CCC5(CC4C(C)(C)O)C(C2)N(CC2CC2)CCC315)C(=O)OC +CC(C)CC(N)c1cccnc1N1CCN(C(=O)C(C)Cc2ccc(Cl)cc2Cl)CC1 +C#Cc1cccc(Nc2ncnc3c2C(=Cc2[nH]c(C(=O)NCCN4CCOCC4)cc2C)C(=O)N3)c1 +COc1cc(C(=O)O)ccc1Cc1cn(C)c2ccc(NC(=O)CC3CCCC3)cc12 +C#CC=CC#CNC(=O)N1CCCN(S(=O)(=O)c2ccc(OCC#CC)cc2)C(C(=O)NO)C1 +CC(=O)OC(OC(=O)c1ccccc1)C1=CC=CC(O)C1OC(C)=O +Clc1cnc(NC2CCCNC2)cc1-c1cccc(NCc2ccncc2)n1 +CC(C)Oc1ccc(Nc2nc(=O)c(C=CC(=O)O)cn2Cc2ccc(Cl)cc2)cc1Cl +CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CCCN(C(=O)Oc2ccccc2)C1 +CCN(CC)c1ccc(NC(=O)Nc2ccc(C(C)=O)cc2)cc1 +CCN1CCC(=NNc2nc3ccccc3s2)c2cc(-c3cccc(C(=O)O)n3)ccc21 +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C1CCC1)CC2 +NCCc1ccc(-c2c(O)cc(Cl)c3[nH]c(=O)c4sccc4c23)cc1Cl +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)CCC1C(=O)N(C)C +CCC(C)c1cc2cc(OC)c(Cl)cc2n1Cc1cccc(C(=O)O)n1 +CC(C)(C)CNc1ncnc2c1ncn2C1OC(CO)C(O)C1O +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)Nc1ccccc1CCO +Cc1c(CCOCCO[N+](=O)[O-])cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1cccc(F)c1 +O=C(CCl)NNC(=O)CSc1nnc(Cc2c(NC(=O)c3ccccc3)sc3c2CCCC3)n1NC(=O)c1ccc(Cl)cc1 +O=S(=O)(NCCCCN1CCN(c2ccc(Cl)cc2)CC1)c1cncc2ccccc12 +COc1cc(F)cc2c1nnc1c(C)nc(-c3ccncc3C)n12 +O=c1[nH]c(N2CCC(F)(F)CC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +Cc1nc(NC(C)c2cncc(-c3cnc(N4CCC(O)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CCN(C)c1nc2ccc(C(=O)N(CC(C)C)CC(O)C(Cc3ccc(F)cc3)NC(=O)OCc3cncs3)cc2o1 +Cc1csc2cc(C(C)Nc3ncnc(N)c3C#N)c(-c3cccc(CNCCN4CCOCC4)c3)c(=O)n12 +CN1C(=O)C(NC(=O)c2cccc(Br)c2)N=C(c2ccccc2F)c2ccccc21 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(OCC4CC(F)(F)C4)c3F)C2)cc1 +O=C(Nc1cccc(Cn2ccnc2C(c2ccccc2)c2ccccc2)c1)c1ccc(Cl)cc1Cl +CC(=O)Oc1ccc2c(c1)C(C)=CC(C)(C)N2Cc1ccc(Cl)c(Cl)c1 +Cn1ccc(Nc2cc(-c3cc(C#N)cc(N4CCNCC4)n3)ccn2)n1 +N#Cc1cccc(C2CCN(c3cc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)CC2)c1 +CC(=O)c1cc2nc(N3CCOCC3)nc(N3CCOCC3)c2s1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(C(O)C3CC3)c12 +N#Cc1ccc(N2N=C(c3ccc(C(=O)O)c(OC(F)(F)F)c3)CC2C2CCCC2)cc1Cl +CS(=O)(=O)N1CCC(Nc2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 +CCC(=O)NCCc1c(OCCO)ccc2ccc(OC)cc12 +CCc1ccc(OC(C)CCOc2ccc(CCC(=O)O)c(C)c2)c(Oc2ccccc2)c1 +COc1ccc(C(Cc2ccccc2)NCC(O)Cc2ccc(O)c(NS(C)(=O)=O)c2)cc1 +NC(Cc1ccccn1)C(=O)N1CCCC1CC(=O)NCc1cc(Cl)ccc1-n1cnnn1 +CN(C)C(=O)c1cccc(-c2ccc3nc(-c4ccccc4)n(-c4ccc(C5(N)CCC5)cc4)c3n2)c1 +COC(=O)c1cc2c(c(C(C)=O)c1C(=O)OC)CCC1C(C)(C(=O)OC)CCCC21C +CN(Cc1ccc(-c2ccccn2)cc1)C(=O)CNC(=O)c1nc2ccccc2n1Cc1ccccc1 +CC1CN(CCOC(c2ccccc2)c2ccccc2)C(C)CN1CCOC(c1ccccc1)c1ccccc1 +COc1ccc(C(F)(F)F)cc1-n1c(CN2CCNCC2)nc2ccccc2c1=O +N=C(N)NCCCC(=O)Nc1ccc(CC(NC(=O)C2CCCCN2S(=O)(=O)c2ccccc2)C(=O)O)cc1 +O=C(O)C1CC(N2Cc3ccccc3CC2=O)c2c(Cl)cc(Cl)cc2N1 +CCc1nc(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)c(C)c2ccccc12 +Cc1ccc(-n2nccn2)c(C(=O)N2CCOCC2Cc2cccc(-n3nccn3)c2)c1 +COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(OC)c(N)c2)c(OC)c1 +O=C(Nc1ccc(C(=O)N2CCN(C(=O)c3ccccc3)CC2)cc1)N1Cc2ccccc2C1 +CN(Cc1cccc(-c2ccc(Cl)cc2)c1)C(=O)CN +COc1cc(CSc2ccc(-c3nn(C)cc3-c3ccncc3)cc2)nc2ccccc12 +Cc1c(C(=O)NCc2ccccc2)[n+]([O-])c2cc(C(F)(F)F)ccc2[n+]1[O-] +Cc1cccc(N(C(=O)c2nsc(Cl)c2Cl)C(C(=O)NC2CCCC2)c2ccc(O)cc2)c1 +O=C(O)C(O)=CC(=O)c1cn(CCCCc2ccccc2)c2ccccc2c1=O +NC(CSC(Cc1ccccc1)(c1ccccc1)c1ccc(Cl)cc1)C(=O)O +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(CO)(Cc5ccc(F)cc5)C4)cc23)ccn1 +CCCN(CCC)C(=O)Cc1c(-c2ccccc2)nc2ccc(C(N)=O)cn12 +COc1c(C)cnc(CN2CC(=O)Nc3c(Cl)nc(N)nc32)c1C +CCN1C(=O)c2c(nc(Cc3ccccc3)n2Cc2ccc(O)cc2)N2CC(Cc3ccccc3)N=C12 +CS(=O)(=O)NC1CCC(Nc2nccc(-n3ccc4c(N5CCN(C(=O)CO)CC5)cccc43)n2)CC1 +CCCC(=O)Nc1cc(C=CC(=O)Nc2cc(C(=O)Nc3ccc(N(CCCl)CCCl)cc3)n(C)c2)n(C)c1 +CC(Nc1cc(Nc2nccc(-c3ccc(C(=O)NO)cc3)n2)ccn1)c1ccccc1 +CC(C)OC(=O)C1=CN(C(=O)c2ccc(OCCCN3CCOCC3)cc2)CC(C)(C)c2c1[nH]c1cc(F)ccc21 +CN1CCC2(C)c3cc(OC(=O)NCc4ccccc4)ccc3N(C)C12 +CN(C)C1CCN(Cc2cc3nc(-c4cccc5nccn45)nc(N4CCOCC4)c3s2)CC1 +CCN(CC)CC1CCCC1c1c[nH]c2ccc(C#N)cc12 +COc1ccc(N(C(=O)CCl)C(C(=O)NCc2ccccc2)c2cccs2)cc1Cl +COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2cccc(C(F)(F)F)c2)CC2CCC1C2 +COc1ccc(-n2cc3nc(-c4cccs4)[nH]c(=O)c3n2)cc1 +CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(Cc1ccccc1)NC(=O)OC1CCSC1 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+O=C(NC1N=C(c2ccccc2)c2ccccc2N(CC(F)(F)F)C1=O)N1CCC(N2Cc3ncccc3NC2=O)CC1 +CCC(C)C1NCCCCC=CCCNC(=O)C(Cc2ccccc2)NC(=O)C(C)N(C)C1=O +CN(C)c1ccc(C#Cc2ncnc(N)c2-c2cccc(Cl)c2)cc1 +C=CCCCC[N+]1(C)C2CCC1CC(CC(C#N)(c1ccccc1)c1ccccc1)C2 +O=C(CCc1ccc(-c2ccccc2)cc1)c1ncc(C(=O)C(F)(F)F)o1 +O=C1NC(=O)C(Cc2ccc(Oc3ncc(Cl)cc3Cl)cc2)S1 +CC1CCC(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)C2CCN(C(=O)c3cccnc3)CC2)CC1 +C=C=CCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1O +CCOC(=O)CNC(=O)N1CCC(CC(=O)N2CCC(C3c4ncc(Br)cc4CCc4cc(Cl)cc(Br)c43)CC2)CC1 +COc1cccc(-c2ccc(C(=O)NC3CCN(CC(F)(F)F)CC3)cn2)c1 +CC(C)N1CC(C(=O)N2CCN(c3ccccc3CC3CCNCC3)CC2)C(c2ccc(Cl)cc2)C1 +NS(=O)(=O)c1ccc2c(c1)CN(C(=O)C1CCCCN1C(=O)COc1ccccc1)CC2 +CCCCCCC(C)(C)c1cc(OC)c2c(c1)OC(C)(C)c1ccc(C(=O)OCCC)cc1-2 +O=C(COc1cccc(-c2ccccc2)c1)Cn1ccc2cc(C(=O)O)ccc21 +O=C(c1ccc(F)cc1Cl)N1CCn2c(-c3ccc(F)cn3)cnc2C1 +CN(C)CCC(O)CNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)(F)C2)CCN1Cc1ccc(F)cc1 +Clc1cc(Cl)cc(CNCCCc2nc3ccc(Cl)nc3[nH]2)c1 +COC(=O)c1cc2occc2n1CC(=O)c1cccc(Cl)c1 +COc1ccc2c(c1)C(CC(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC1CCc3ccccc31)CC2=O +Cn1c(=O)[nH]c2c(Oc3ccc(NC(=O)Nc4cc(C(C)(C)C)nn4-c4ccccc4)cc3)ccnc21 +O=C(Nc1cccc(-c2c[nH]cn2)c1)c1ccc2cc3n(c2n1)CCCNC3=O +CCCOc1ccccc1N1CCN(Cc2nc3c(C(=O)NC4CN5CCC4CC5)cccc3[nH]2)CC1 +Cc1ccc(COc2ccc(S(=O)(=O)N3CC(O)CC(C)(C)C3C(=O)NO)cc2)cc1 +CN1CC2CC1CN2c1ncc(-c2ccc3sccc3c2)cn1 +Cc1cc(=O)oc2cc(OCCCCN3CCC(C(=O)c4ccc(F)cc4)CC3)ccc12 +Cc1c(C(=O)N=C(N)N)cc(S(C)(=O)=O)c(Cl)c1[N+](=O)[O-] +CCn1nc2c(n1)C(N1CCN(C)CC1)=Nc1cc(F)ccc1N2 +Cc1nn(Cc2ccc(-c3nc4cc5ccccc5cc4[nH]3)cc2)c(C)c1CC(=O)O +Cc1cnccc1COc1cc(C(CN)CC(=O)O)ccc1Cl +COc1cccc(Oc2ccc3c4c(C#N)c(=O)nc-4c4cccc2c43)c1 +O=c1[nH]c2ncc(-c3ccc(O)cc3)nc2n1CC1CCOCC1 +CN(C)c1ccc(C=CC=C2C(=O)Nc3ccc(O)cc32)cc1 +COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN2CCN=C2C)c1Cl +Cc1ccn(-c2ccc(C(=O)N3Cc4cnn(C)c4Nc4ccccc43)cc2C)n1 +CC(C)C12OC1C1OC13C1(OC1CC1(Cl)C4=C(CCC13C)C(=O)OC4)C2=O +CC1(O)C(O)C(CO)OC1n1cc(-c2cc[nH]n2)c2c(N)ncnc21 +C#Cc1cc(Nc2ncnc3cc(OC)c(OC)cc23)ccc1F +N#Cc1cc(NCC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)ccc1F +NC(=O)c1ccc(NC2CNCC2c2cccc(OC(F)(F)F)c2)c2cccnc12 +CN1CCN(c2ccc(C(=O)NC(Cc3ccccc3)C(O)CNCc3ccc(O)c(CN4CCCC4)c3)cc2)CC1 +CCN(CC)c1cc2oc(=O)ccc2cc1-c1ccc(Cl)cc1 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(C)C)cc2)cs1 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 +Cc1ccc(S(=O)(=O)N(CCCC(C)C)c2cc(Cl)ccc2CO)cc1 +COc1cc(Cl)ccc1OC(c1ccccc1F)C1CNCCO1 +COc1ccc(S(=O)(=O)N2CC(C(=O)NC3CC4CCC(C3)N4C)c3ccccc32)c2ccccc12 +COc1cc(S(=O)(=O)c2ccccc2)cc2c3c(oc12)CCNC3 +Cc1nc(-c2cn3c(n2)-c2ccc(OC4(CC(C)C)CN(C(C)C)C4)cc2OCC3)n(C(C)C)n1 +Cn1c2c(c3ccccc31)C1CCC(C2)N1CCCC(=O)c1ccc(F)cc1 +CN1Cc2c(c(O)c3ncc(Cc4ccc(F)cc4)cc3c2N(C)S(C)(=O)=O)C1=O +CC(C)(C)C(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +COc1cc(NC(=O)C(C)c2cccc(F)n2)ccc1-c1ccnc(C)c1 +C#CCN(C)C(C)Cc1ccc(OCCCCCCNc2c3c(nc4ccccc24)CCCC3)cc1 +O=C1C(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCCN1CC(=O)N1CCCC1c1cccnc1 +CS(=O)(=O)c1ccc(C2=C(Oc3ccccc3)C(=O)CC2)cc1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1-c1ccco1 +Oc1ccc(C2=COc3cc(O)c(CNCCc4ccccc4)cc3C2)cc1 +CC(C)c1ccc(COc2ccc(C=NNC(=O)c3ccc(O)c(Cl)c3)c3ccccc23)cc1 +CCCn1c(-c2ccc(C(C)C)cc2)nc2c(C)ccc(OC)c21 +COc1cc(C(=O)Nc2ccc(NC(=O)C3CCCCN3)cc2)cc(-c2c[nH]c(=O)[nH]c2=O)c1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccc(I)c([N+](=O)[O-])c1 +CN(C)C(=O)c1sc2[nH]nc(N3CCC(COCCN4CCCC4)CC3)c2c1-c1ccccc1 +CC#CC(=O)N1CCC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccc(F)cc5)cc4)nn32)CC1 +CN(C)CC1(c2cccc(F)n2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +CCN(C)C(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(N(CCCN(C)C)C(C)=O)cc1)c1ccccc1 +Cc1ccc(-n2nc(C3CCN(C4CCC(N(C)S(C)(=O)=O)CC4)CC3)cc2NC(=O)c2cnn3cccnc23)nc1 +Fc1ccc(C(CCNc2ncnc3c2[nH]c2ccccc23)c2ccco2)cc1 +CCn1cc(CC(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(-c3ccccc3)ccc21 +O=c1[nH]nc(CCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1O +CNc1nc(Nc2ccccc2)nc(NC2(C#N)CCCCC2)n1 +Cc1nnc(CNC(=O)c2cc(NC(=O)c3cc(-c4ncccc4F)ccc3Cl)n(-c3ccccc3)n2)o1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)OC +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(CC(=O)O)C(=O)O +CCOC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCc1cccc(F)c1 +COc1ccc2c(c1)CC(c1nc3c(F)cc(-c4ccnc(N)n4)cc3[nH]1)CO2 +O=C(C=Cc1ccc(Cl)c(Cl)c1)NCCCCCCN1CCN(C(=O)Nc2ccc(Cl)c(Cl)c2)CC1 +O=C(NO)c1cnc(Nc2nnc(-c3ccc([N+](=O)[O-])cc3)o2)nc1 +Cc1nc(NC(C)C)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CCCCC(CN(O)C=O)C(=O)NC(C(=O)c1ccccc1)C(C)(C)C +COC(=O)C1CCC(CN(Cc2ccc(OCCN3C(=O)CCC3=O)c(OC)c2)C2CCc3cc(Cl)ccc32)CC1 +CC1(C)N=C(N)N=C(N)N1OCCOc1cccc(C(=O)C=Cc2ccccc2)c1 +CN(C)C(=O)c1ccc(-c2ccc(O)c(C=O)c2)cc1 +CCC(CC)NC(=O)CCc1cc(-c2cccc(C(F)(F)F)c2)nc(C#N)n1 +CC#Cc1cncc(-c2ccc3c(c2)C2(COC(N)=N2)C2(COC2)C(C)(C)O3)c1 +CCN1CCN(C(=NO)c2cnc(C#CC3(CN4Cc5ccc(OC)cc5C4=O)NC(=O)NC3=O)c(OC)c2)CC1 +COc1ccccc1N1CCN(CCCn2nnc3ccccc32)CC1 +CCC(NC(=O)c1ccc2nc(NC3CCC(O)CC3)c3nccn3c2c1)c1ccccc1 +Cc1csc(NC(=O)c2cc(Sc3ccccn3)ccc2N)n1 +COc1cc(NC(=O)N2CCc3nc(-c4ccc(Cl)nc4)nc(OC4CCOC4)c3C2)ccn1 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+COc1ccc(N2CCN(C(CNS(=O)(=O)c3cc(F)ccc3F)c3cccnc3)CC2)cc1 +CCCCNC(=O)C(C)CC(O)C(N)CN(C(=O)c1ccc(OC)c(CCCCOC)c1)C(C)C +Cn1c(CNc2cccc(C(=O)NCc3cccc(C(F)(F)F)c3)c2)nnc1-c1ccncc1 +CC(=O)c1cn(CC(=O)N2CC(F)CC2C(=O)NCc2cccc(Cl)c2F)c2cc(CO)ccc12 +CNC(=O)c1cnc(N)c2cc(-c3ccc(S(=O)(=O)NC(C)(C)C)cc3)sc12 +CC(C)(C)OC(=O)n1c(-c2ccc3c(c2)CC(NS(C)(=O)=O)C3)cc2ccccc21 +FC(F)(F)c1cnc2[nH]c3ccc(C4CNCCO4)cc3c2c1 +CCc1ccc(Cc2sc(C3OC(CO)C(O)C(O)C3O)cc2C)cc1 +c1ccc(-c2nnc3c4c(c(OCc5nccs5)nn23)C2CCC4CC2)cc1 +Cc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +COc1cc(OCc2csc(-c3ccc(C(=O)N4CC(OC)C4)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3nccn3C)cc2)c1C +O=C(CN1CCCc2ccccc21)N1CCN(c2scnc2-c2nc3ccccc3[nH]2)CC1 +O=C(Cn1ccc(-c2ccc(C(=O)NO)s2)n1)Nc1cccc2cccnc12 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NCc4ccccc4F)nc23)N1 +Cn1cc(-c2ccc(-c3cncc4ccc(S(N)(=O)=O)cc34)cc2)cn1 +CS(=O)(=O)c1ccc(C2C(Oc3ccccc3)C(=O)N2c2ccc(Cl)cc2)cc1 +O=S(=O)(c1cccc(Cl)c1)n1cc(C2=CCCNC2)c2ccccc21 +COc1ccccc1-c1cc2c(NCc3ccncc3)ncnc2s1 +CC1CC(C)CN(C(=O)c2cc(Br)ccc2NC(=O)CCC(=O)c2ccccn2)C1 +Nc1ncc(-c2cnc3sc(-c4cccc(S(=O)(=O)N5CCOCC5)c4)nn23)cc1C(F)(F)F +COc1cc(OCc2csc(N3CCC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(N4CCCCC4)nc23)N1 +Cc1c(Cl)cccc1S(=O)(=O)N1CCCC1(C)C(=O)NC1C2CC3CC(C2)CC1C3 +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(OC)cc1)C(=O)C1CCC1 +COc1ccc(C(NC(=O)c2ccc3cnc(Nc4ccnn4C)nc3c2)c2ccnn2C)cc1F +CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)C2CC=C(C)CC32)CC1(Br)Br +Cc1cc2c(-c3ccc(S(=O)(=O)NC4CCS(=O)(=O)CC4)cn3)ccnc2[nH]1 +CNC(C)C(=O)NC1C(=O)N(Cc2c(C)cnc3ccccc23)c2ccccc2N(C(=O)CS(C)(=O)=O)C1C +Cc1c(O)ccc(C=NNc2ncccc2[N+](=O)[O-])c1O +O=C(Nc1ccc(Oc2ccnc3cc(-c4cn(CCCN5CCCC5)cn4)sc23)c(F)c1)N1CCN(c2ccccc2)C1=O +CS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCNCC(O)c3ccc(N)cc3)cc2)cc1OC1CCCCC1 +COc1cc(OC)cc(N(CC2CCCO2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Oc1ccc(CN2CCC(COCc3ccc(F)cc3)CC2)cc1 +CCCCCCN1CC(C)C(C)(c2cccc(O)c2)CC1CCC +O=S(=O)(c1cccc(CCCCOCCCCCCNCC(O)c2ccc(O)c(CO)c2)c1)N1CCCCC1 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+FC(F)(F)c1cccc(N2CCN(CCC3CCC(Nc4ncccn4)CC3)CC2)c1 +CCCCCCS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O +OC(COCc1ccccc1)CN1CCC2(CC1)OCc1c2ccc2ccccc12 +NS(=O)(=O)c1ccc(N2N=C(c3cccs3)CC2c2ccc(C(F)(F)F)cc2)cc1 +Nc1nc(-c2cccc(F)c2)nc2sc(Cc3ccccc3)cc12 +CC(=O)NCc1cc(-c2cc3nc(NC4CC4)c4ncn(C)c4n3n2)ccc1F +CC(C)NCc1cc(NC(=O)Nc2cccc3c2C2CCCN2C3=O)[nH]n1 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C4CCN(C)CC4)cc3)cc12 +O=C(Nc1ccc(-c2nnc(NCCCCN3CCC(F)CC3)o2)cc1)c1ccccc1F +COc1ccc2cnc(Nc3ccccc3)nc2c1C1CCCC1 +O=C(Nc1ncc(CCNc2ncnc3ccsc23)s1)NC1CCCCC1 +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1NN=C(C)C +COc1cc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)ccc1OCC1CCCN1 +COc1ccc2nc(C(=O)Nc3ccc(C4CCNC4)cc3)ccc2c1 +CC(C)CCN(CC(O)C(Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)OCc1ccccc1)C(=O)NC(C)(C)C +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc2cc(F)ccc2c1 +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCN(C(=O)C2CCC2)C1 +O=C(C1CC(N2CCN(c3ccnc4ccccc34)CC2)CN1)N1CCSC1 +N#Cc1ccc(N2CCN(CCNC(=O)c3ccc(F)cc3)CC2)cc1 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+CCCCN(CCCCCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)[nH]1)c1nc2ccccc2o1 +Clc1ccc2c(NCCCN3CCN(CCCNCCCc4ccccc4)CC3)ccnc2c1 +Cc1cc(=O)oc2c(OCCCN(C)C)c3oc4ccccc4c3cc12 +CC(C)(CCC(C(N)=O)(c1ccccc1)c1ccccc1)N1CC(Oc2ccc(Cl)c(O)c2)C1 +Cc1noc(C)c1Cn1cc(C)c2cc(F)cc(C=CC(=O)NS(=O)(=O)c3ccc(F)c(F)c3)c21 +Cc1[nH]c(-c2cc(Cl)ccc2Cl)nc1C(=O)N=C(N)N +COc1ccc(C(C)(C)C)cc1Cn1c(C(=O)NCC2(CO)CC2)cc2cc(C#N)ccc21 +COc1cc(-c2cc(=O)c3cc(Br)cc(Br)c3o2)ccc1O +CC1CN(Cc2cccnc2)CC1c1nn2c(C3CCOCC3)ncc2c(=O)[nH]1 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)c3c(Cl)cncc3Cl)CC2)cc1 +CNCC(=O)NC(CC(C)C)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)N2CCCC2=O)CC1 +CN1CCN2c3c(cccc31)C1CCN(CCCC(=O)c3ccc(F)cc3)CCC12 +O=C(Cn1nc2ccccc2n1)NCC1CCCN2CCCCC12 +Cc1ncnc(-c2ccc(S(C)(=O)=O)cc2)c1C#Cc1ccc(N)nc1 +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3ccccc3F)ccc21 +COc1ccc2c(c1)-c1nc(N)nc(-c3ccc(Br)o3)c1C2 +O=C(Nc1cncc(C(=O)c2cn(C(CO)CO)c3ncncc23)c1)c1cccc(OC(F)(F)F)c1 +O=c1nc2oc(CCCCCCCCCOCCCCCl)cc2cn1C1CC(O)C(CO)O1 +N#Cc1ccc(C(=O)Nc2ccc(C3CNCCO3)cc2Cl)cn1 +CN(C)C(=O)C(NC(=O)C(CN(O)C=O)c1ccc(Cl)cc1)C(C)(C)C +CNC1CCN(c2ccc(-n3ncc4cc(-c5ccc(Cl)cc5)sc4c3=O)cn2)C1 +COc1cc2c(cc1OC)CN(CCCCNC(=O)c1cn(Cc3ccc(O)cc3)nn1)CC2 +Cc1cc(-c2ncc(CNC(=O)c3ccc4c(c3)[nH]c3ccccc34)cc2C)ccn1 +Cc1ccccc1C=c1[nH]c(=O)c(=Cc2ncoc2C(C)(C)C)[nH]c1=O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(-n5cccn5)cc4F)nc23)N1 +O=c1[nH]cnc2ccc(Cc3nnc4ccc(-c5ccccc5)nn34)cc12 +CC(C)c1nn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-n3cnc(-n4ccnc4)c3)c12 +CCc1ccc(CN2CCc3c(c(=O)n(CCN(C)CCc4ccccn4)c(=O)n3Cc3c(F)cccc3F)C2)cc1 +CN1CCC(O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)sc2C2CC3C2)C1=O +O=c1oc2ccccc2c2nc3c(c(-c4ccccc4)c12)CCCC3=Cc1ccccc1 +O=S(=O)(c1ccc(Cl)cc1)C1(c2cc(F)ccc2F)CCC(CO)CC1 +CCc1cc(C(F)(F)F)nn1-c1nc(-c2cccc3[nH]ccc23)nc(N2CCOCC2)n1 +CCNC(=O)N1CCCC12CCCN(c1ncnc3[nH]ccc13)C2 +C=CCNCC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1 +COc1ccc(C(=O)NC2CCN(CCn3c(=O)ccc4ncc(F)cc43)CC2)cc1Cl +CC(C)CC(NC(=O)c1ccc2ccccc2c1)C(=O)NC1CCOCC1=O +O=C(NCC1CCOC1)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CCCc1cc(Oc2ccc(S(C)(=O)=O)cc2)ccc1OCCCOc1ccc(C2SC(=O)NC2=O)cc1 +Cc1ccc(-[n+]2c(-c3ccc(Br)cc3)cn3c2CCc2ccc4cccnc4c2-3)cc1 +CC(C)C(NC(=O)Cn1c(-c2ccc(F)cc2)ncc(N)c1=O)C(=O)c1nnc(-c2ccccc2)o1 +Fc1ccc(-c2[nH]c(SCCCc3ccccc3)nc2-c2ccncc2)cc1 +CN(c1nc2ccccc2[nH]1)C1CCN(CC2=CCC3CC2C3(C)C)CC1 +O=C(NCCCCN1CCN2c3ccccc3CCC2C1)c1ccc2ccccc2c1 +Cc1oc(-c2ccccc2)nc1CN1CC(C(=O)NCc2cccc(N)n2)CC(c2ccccc2)C1 +NC1(c2ccccc2)CCC(N2CC(NC(=O)CNC(=O)c3cccc(C(F)(F)F)c3)C2)CC1 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OCC(=O)NCC(=O)O)cc2)C1O +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C(CO)C(N)=O +CC(C)CNc1nc(C#Cc2ccccc2F)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +CC1=CCC2C(C1)c1c(O)cc(C(C)(C)c3ccc(C)cc3)cc1OC2(C)C +Cn1nc(-c2ccc(F)cc2)c(-c2ccc3nc(NC(=O)c4ccncc4)cn3n2)c1C1CCN(Cc2nccs2)CC1 +NC(=O)N1CCCc2cc(-c3cncc(-c4cc[nH]n4)c3)cnc21 +CC(C)N1CCN(c2nc(-c3ccncn3)cc(=O)n2C)C(C)C1 +COc1ccc(I)c(Sc2nc3c(N)ncnc3n2CCCNC(C)C)c1 +COc1cc(N2CCN(S(C)(=O)=O)CC2)ccc1Nc1ncc2ccn(C3CCCCC3)c2n1 +CCOC(=O)C1CC1Cc1c(Br)c(Br)c(OC)c(OC)c1Br +Cc1noc(NS(=O)(=O)c2sccc2-c2ccc(C(C)C)cc2)c1Br +O=C(O)C1(O)CCN(c2nc3ccccc3n(C3CC4CCC(C3)N4C3CCCCCCC3)c2=O)C1 +CCCCOP(=O)(O)C1=CC(OC(CC)CC)C(NC(C)=O)C(N)C1 +CCOc1ccccc1OCCN1CCN(c2cnn(CCCCCCCN3CCN(c4ccccc4OC)CC3)c(=O)c2Cl)CC1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(C=O)c(O)ccc3nc2-1 +O=C(C=Cc1ccc(O)c(O)c1)c1ccccc1-c1cccnc1 +CCc1cn(C2CC(n3cnc4c(NCC(CC)CC)nc(NCCc5cn(CC)cn5)nc43)C(O)C2O)nn1 +CN1CCC23c4c5ccc(O)c4OC2C(NC(=O)COCC(=O)O)CCC3(O)C1C5 +O=C(O)CCSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O +O=C(c1cc(F)ccc1-n1nccn1)N1CCC2CN(c3nc4cc(Cl)ccc4o3)C2C1 +Cc1cccc(-c2nn(CC(=O)Nc3cccc(C(N)=O)c3)cc2-c2ccc3nccnc3c2)n1 +O=C(NC(c1ccc(Cl)c(Cl)c1)C1CCNCC1)c1ccc2cnc(Cl)cc2c1 +O=C(O)C1C2c3ccccc3C(c3ccccc32)C1C(=O)NCC1C2CC3CC(C2)CC1C3 +N#Cc1cnc(NC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)s1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)c2n1CCOC2)c1ccccc1Cl +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CN(C(=O)OCc2ccccc2)C1 +COC(=O)C1CC(NC(=O)c2ccc(OC)cc2OC)CN1Cc1ccc(C)cc1C +CCOC(=O)c1ccc(C=C2c3ccccc3C(=O)c3ccccc32)cc1 +CCOC1Oc2ccc(F)cc2C(=O)C1=CNc1cccc(S(N)(=O)=O)c1 +O=C(O)Cc1cccc(-c2ccn(C(F)F)c(=O)c2)c1 +O=C(c1ccoc1)N1CCN2C(=O)c3ccncc3C12c1ccc(Cl)cc1 +CCNC(=O)Nc1ccc(-c2nc(N3CC4CC3CO4)c3c(cnn3C)n2)cc1 +COc1ccc(C(=O)Nc2c(Cl)cc(C#N)cc2Cl)c2cc(C(C)=O)oc12 +CCCCn1c(=NC(=O)c2cc(C(F)(F)F)ccc2ONC(C)(C)C)cc(C(C)(C)C)n1C +Cc1ccc(COc2ccc(S(=O)(=O)N3CCC(O)CC3C(=O)NO)cc2)cc1 +N=C(N)c1cccc(NC(=O)Nc2ccc(S(=O)(=O)NCc3ccc(S(N)(=O)=O)cc3)cc2)c1 +O=c1[nH]n(Cc2ccno2)c(=O)c2c(=O)c3ccc(Cl)cc3[nH]c12 +CC(COc1cc(N)nc(N)n1)Nc1ccnc2cc(Cl)ccc12 +[C-]#[N+]c1ccc(N2C(=O)C(C)(C)N(c3ccc(C)cc3)C2=S)cc1C(F)(F)F +Cc1ccnc(Oc2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)n1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(Cl)cnc1NCc1nccs1 +CCCCCCC1C(=O)NC(C(=O)O)(C(O)C2C=CCCC2)C1(C)O +Cc1cc(N)nc(C)c1CNC(=O)c1cc(Cn2ccc3ccccc3c2=O)oc1C +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(N1C(=O)CCC1C(=O)O)C2 +CN1C(=O)CCc2cc(-c3cncc(COc4ccccn4)c3)ccc21 +Cc1c(NC(=O)c2ccc(C3CC3)cc2)cccc1-c1cn(C)c(=O)c(Nc2ccc(C(=O)N3CCOCC3)cc2)n1 +COc1cccc(CCC2CCCCN2C(=O)c2cc(C)ccc2-n2nccn2)c1 +CC(C)CN(Cc1ccc(N2CC3COCC3C2)cc1)S(=O)(=O)Cc1ccccc1 +CC(C)n1c(=O)c(C(=O)NC2CC3CCC(C2)N3CCCCCS(=O)(=O)O)cc2ccccc21 +COc1ccc(C(=O)NN(C(=O)c2ccccc2Cl)C(C)(C)C)cc1 +Cc1noc2c(F)c3c(cc12)CC1(C(=O)NC(=O)NC1=O)C1C(C)CC(C)CN31 +Cc1ncc([N+](=O)[O-])n1CCNC(=S)Nc1ccc(S(N)(=O)=O)cc1 +CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(N=C=S)cc12 +O=C(CN1CCC(C(=O)c2ccc3c(c2)CCO3)CC1)NCc1nc2c(c(=O)[nH]1)COCC2 +Cc1nnc(SCC(=O)Nc2ccccc2Br)n1-c1cccc2cccnc12 +OCC1OC(n2cnc3c(SCc4ccccc4Br)ncnc32)C(O)C1O +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2CN2CCOC2=O)o1 +CNc1nc(C2CCCCC2)nc(N2CCC(C(=O)NCc3ccccc3C(F)(F)F)CC2)n1 +COCCN1C(=O)NC2(C1=O)c1cc(C#N)ccc1CC21CCc2ccccc2CC1 +CCC(=O)c1ccc2c(c1)sc(=O)n2CCN1CCCCC1 +COc1cc(Nc2ncc3ccn(-c4cccc(C(=O)NCC#N)n4)c3n2)cc(OC)c1OC +O=C(NC1CCCC1Nc1ncc(C(F)(F)F)nc1C1CC1)c1ccccc1-n1nccn1 +Cc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(C=Cc5ccccn5)n[nH]c4c3)c2)cc(Cl)n1 +O=C(CN1CCCCC1)Nc1cccc(-c2cnc3ccccc3n2)c1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1-c1ccco1 +CC(C)S(=O)(=O)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +COc1ccc(C(=O)C(=NC2CCCC2)n2ncc(C#N)c2N)c(OC)c1 +CC(C)(C(=O)NC1CC2CC(C1)CC(C(N)=O)C2)N1CCN(c2ccc(C(F)(F)F)cn2)CC1 +COC(=O)C1C2CCC3CCC1N(CC2=Cc1ccc(-c2ccc(Cl)cc2)cc1)C3 +CCC(N)C1CCN(c2c(F)cc3c(=O)n(N)c(=O)n(C4CC4)c3c2C)C1 +CC(C)(C)c1cccc(CNC2C[S+]([O-])CC(Cc3cc(O)c(N)c(F)c3)C2O)c1 +O=C(c1ccc2ccccc2c1)N(C1CCC1)C1CCNCC1 +N=C(N)Nc1ccc(CNC(=O)CC(=O)NCc2ccc(CNC(=O)CC(=O)NCc3ccc(NC(=N)N)cc3)cc2)cc1 +CC1CN(c2ccc([N+](=O)[O-])cc2)CCN1S(=O)(=O)c1ccc(C(C)(C)C)cc1 +CC(C)(N)C(=O)N1Cc2n[nH]c(=O)c3cccc4[nH]c(c2c43)C1 +COc1cc(-c2nc(C)nc3[nH]cc(C#N)c23)c(Cl)cc1Cl +FC(F)(F)c1ccc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)oc3c2)cc1 +Cn1c2c(c3ccc(-n4ncc(OCc5ccc(C(F)(F)F)nc5)cc4=O)cc31)CCNCC2 +COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCNCC5)o4)sc23)c(Cl)cc1Cl +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(C(=O)NCCN4CCOCC4)cc3OC)ncc2Cl)c1 +CCCCc1nc2ccc(C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2cccs2)cc1 +CCN(CC)CCCCNC(=Nc1ccnc2cc(Cl)ccc12)C(C)C +CC(=O)c1ccc2[nH]c(-c3ccc(-c4ccc([N+](=O)[O-])cc4)cc3)nc2c1 +COc1nc2ccc(C(O)(c3cnnn3C)c3cnc(C)n3C)cc2c(C#N)c1Cc1ccc(C(F)(F)F)cc1 +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4cc(OC(F)(F)F)ccc4[nH]3)CC3CC123 +COc1ccc2c(c1)c(CC(=O)N1CCOCC1)c(C)n2C(=O)c1ccc(Cl)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NCC3CC(C(C)(C)O)C3)c2cn1)c1ccccc1 +Cc1cc(F)ccc1C1CNCCN1C(=O)N1CCCC1c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC1(C)CC1C(=O)NC(=CCCCCC(=O)O)C(=O)O +CNC(=O)NCc1ccccc1-c1ccc(CN2C(=O)C(NC(=O)CC(C)(C)N)CCc3ccccc32)cc1 +COc1ccc(-c2cc3c(NC(=O)C(C)C)ncnc3o2)cc1 +CCNC(=O)N1CC(OC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(c2ccc(F)cc2)C1 +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)cc1F +Cc1csc(-n2[nH]c3c(cnc4cc(C)ccc43)c2=O)c1 +COc1ccc(C(=O)N2CCC(CNCc3cccc(-n4cccn4)n3)CC2)cc1Cl +Cc1ccc(COC(c2ccc(C#N)c(-c3ccccc3C)c2)c2cncn2C)cc1 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+[C-]#[N+]c1c[nH]c2ccnc(Oc3ccc(-c4c(C)ncnc4C)c(C)c3)c12 +COc1ccc(F)c(-c2nc(C(=O)Nc3cnn(C)c3C3CCC(N)C(OC)CO3)cs2)c1F +O=c1oc2ccccc2c(O)c1C1c2ccccc2Oc2c1c(=O)oc1ccccc21 +CN1CCN(Cc2ccc3c(c2)Cc2c(-c4ccc(C#CCOc5ccccc5)s4)n[nH]c2-3)CC1 +CCOC(O)=C1C(COCCNC(=O)c2ccc(O)nc2)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +Cn1c(=O)c(Cc2ccc(C(=N)N)cc2)nc2cc(C(C)(C)C(=O)N3CCCC3)ccc21 +CN(C)c1ccc(-c2nc3cccnc3n2-c2ccc(CC(NC3=C(Br)C(=O)C34CCCCC4)C(=O)O)cc2)cn1 +CN1CCC23Cc4nc5cc(F)ccc5cc4CC2(O)C1Cc1ccc(O)cc13 +O=C(NO)C(NCc1cccc(C(F)(F)F)c1)c1cccc2ccccc12 +COc1cc(N2CCOCC2)ccc1Nc1nc(Nc2ccccc2S(=O)(=O)C(C)C)c2cc[nH]c2n1 +COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cn(C)c(=O)n(C)c2=O)C3=O)c(OC)n1 +COCOc1ccc(C(=O)C(CCC2CCN(Cc3cccc(C)c3)CC2)C(C)=O)cc1OC +CCC1=C2C(Nc3ccc4c(cnn4Cc4ccccc4)c3)=NC=NC2N=C1NC(=O)OCC1CCCNC1 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCCC2)CCNC1 +CC(C=Cc1ccc(Oc2ccc(F)cc2)o1)N(O)C(N)=O +O=C(Nc1noc2ccccc12)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +Cc1ccc(-n2c(-c3ncccc3Cl)nc(CNC3CCCC3)c2C)cn1 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+NC1CN(c2ncnc(N3CCC(F)(F)C3)n2)CC1N1CC(F)(F)CCC1=O +CCOC(=O)c1cn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)n1 +CC12CCC(=O)C=C1CCC1C2CCC2(C)C(O)CCC12 +Fc1ccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)cc1 +CC(OCC(c1ccccc1)N1CCN(CC(=O)O)CC1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=C(CSC(c1ccc(Br)cc1)c1ccc(Br)cc1)NCCCCc1ccccc1 +CN(CCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N1CCCC1)CC2)S(=O)(=O)C1CCC1 +O=C(O)c1ccc(S(=O)(=O)Oc2ccc(C=C[N+](=O)[O-])cc2)c(O)c1 +O=C(c1cccc(C#Cc2ccccn2)c1)N1CCN(c2ccccn2)CC1 +Cc1ccsc1-c1nn(CCC(C)C)c(=O)c(C2=NS(=O)(=O)c3cc(OCC(N)=O)ccc3N2)c1O +CCCn1c(C)c(C(=O)c2ccc(OC)c3ccccc23)c2ccccc21 +COc1cccc(Nc2nc3c(-c4nnc[nH]4)cccc3c3cnccc23)c1 +CC(C)(C)c1[nH]nc2c1C(c1ccccc1OCCO)N(c1ccc(-c3ccoc3)cc1)C2=O +COc1cccc2c3c(c(C)nc12)CCN3c1ccccc1 +COc1cc(NC(=O)c2ccc(C)c(Nc3ncnc4c(N)nc(N5CCN(C)CC5)nc34)c2)cc(C(F)(F)F)c1 +Nc1ncnc2c(CN3CC(O)C(O)C3CO)c[nH]c12 +Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2C)c(C(F)(F)F)c1 +CC1(C)CC(O)CN(S(=O)(=O)c2ccc(OCc3cc(Cl)ccc3F)cc2)C1C(=O)NO 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+COc1cc(Nc2nccc(Nc3ccc4nccnc4c3)n2)cc(OC)c1OC +CNc1nc(Nc2cc(F)c(-c3nnnn3C)cc2OC)ncc1C(F)(F)F +COc1ccc(CNc2nc(Cl)c(SC)c(N3CCN(C)CC3)n2)cc1 +COC(=O)CCC#Cc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +CCOC(=O)c1c(C)nc2c(cnn2CCCC(C)(C)C)c1N +O=c1[nH]c(C2CC(O)CN2)nc2c1oc1ccc(Br)cc12 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(S(=O)(=O)c2ccco2)CC1 +N=C(Nc1cccc(C2(O)CCN(CCc3ccc(Cl)c(Cl)c3)CC2)c1)c1cccs1 +COC(=O)C1CCC(C(=O)NCCCc2ccccc2)CC1 +CC1=C(N2CCC3(CCN(CC(O)c4cc5c(cc4Cl)Cn4nnnc4-5)CC3)C2=O)COC1=O +Cc1cc(OCc2ccc3c(-c4nnn[nH]4)cc4ccccc4c(=O)c3c2)c2c(n1)CCCC2 +O=C1C(O)Cc2c(-c3ccccc3Cl)cc(O)cc2N1c1c(Cl)cccc1Cl +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2ccc(C(=O)N3CCNCC3)cc2Cl)n1 +O=C(NCc1cccn2c(=O)c(O)c(C(=O)NCc3ccc(F)cc3)nc12)c1ccccc1 +NC(CC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)Cc1cc(F)c(F)cc1F +Cn1cccc1-c1nnc2n1CCN(C(=O)c1cccc(Cl)c1Cl)C2 +O=C1CCCC(=O)C1=C(O)c1ccccc1[N+](=O)[O-] +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Cl)cc1F +Brc1cnc(Nc2ccccc2Cc2ccccc2)nc1Nc1cc(C2CC2)[nH]n1 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+O=C(CCCCCCCCCCS)Nc1ccc(CCCN2CCN(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +CCOc1ccc2c(c1)Oc1cc(O)ccc1C21c2ccccc2C(=O)N1N=Cc1ccccc1OC +C[N+](C)(C)Cc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +CC(=O)OC1CC2C(CCC3CC4(CCC32C)OOC2(CCC(C)CC2)OO4)C2CCC(C(C)CCC(=O)O)C12C +CC(Cl)(Cl)C(NC(=O)c1ccc(I)cc1)NC(=NC#N)Nc1ccc(Cl)nc1 +Cc1cc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)sn1 +Cn1cc(C=C2Oc3cccc(O)c3C2=O)c2c(-c3ccc(C(=O)N4CC5CCC(C4)O5)cc3)ccnc21 +COc1cc(-c2ccc(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncccn5)ccc43)c(OC)c2)ccc1Cl +CCCN1CCC(c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C)cc3)n2)CC1 +CON(C)C(=O)c1ccc(-c2csc3c(N(C)C4CCN(C(=O)OC(C)(C)C)CC4)ncnc23)cc1F +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCN(C(=O)N2CC(C#N)C2)C1 +Cc1nc(-c2ccc3c(c2)c(Cl)c(C)n3CC(C)C)sc1C(=O)O +O=C1NCCN1CCN1CCC(n2cc(-c3ccc(F)cc3)c3ccc(Cl)cc32)CC1 +N#Cc1cccc(-c2cc(C(=O)NC3CCCNC3)c(NC(N)=O)s2)c1 +COc1cc(OC)nc(N2CC3CN(C(=O)c4cc(F)ccc4-n4nccn4)CC3C2)n1 +CC(=O)c1cccc(CNc2cc(C(F)(F)F)cc3ncc(N4CCN(C)CC4)cc23)c1 +O=C(c1ccc(Cl)cc1)N1CCc2c(n(Cc3ccc(O)cc3)c3ccccc23)C1 +COc1cc2oc(-c3ccc(O)c(O)c3)c(OC)c(=O)c2c(O)c1OC +Cn1ccc2c(Nc3cccc(Cl)c3)ncc(C(=O)N3CCOCC3)c21 +Cc1cccc(-c2[nH]c(CNC(=S)c3cccc(C#N)c3)nc2-c2ccc3ncnn3c2)n1 +O=C(NC1N=C(c2ccccc2)c2ccccc2N(CC(F)(F)F)C1=O)N1CCC(N2CCNC2=O)CC1 +COc1cc2c(Oc3ccc(-c4cnc(Nc5ccccc5)n(C)c4=O)cc3F)ccnc2cc1OCCCN1CCOCC1 +CC=CC(C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +CN(C)CCn1nc2c3c(c(NCCC4CCCN4C)ccc31)C(=O)c1ccncc1-2 +O=S(=O)(Cc1cccc(OCc2ccc(CN3CCCC3CO)cc2)c1)c1ccccc1 +COc1ccc(-c2c3nc(cc4ccc(cc5nc(cc6ccc2[nH]6)C=C5)[nH]4)C=C3)cc1 +O=C(Nc1ccc(S(=O)(=O)N2CCC(O)CC2)cc1)c1ccc([N+](=O)[O-])o1 +CN(C)CCSc1c(S(=O)(=O)c2ccccc2)no[n+]1[O-] +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccc4cc[nH]c4c3)sc12 +O=C(CO)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)CC12CC3CC(CC(C3)C1)C2 +Cn1nc(-c2ccc(C(=O)O)cc2)sc1=NC1CCCCC1 +Cc1ccc(Oc2ccc(C(=O)c3nc(C(=O)O)cc4cc(O)c(O)cc34)cc2F)cc1 +N#Cc1cccc(-c2c[nH]c3ncc(-c4cncc(NS(=O)(=O)c5ccccc5)c4)cc23)c1 +NC(=O)N1CCCc2cc(-c3cncc(CC(=O)N4CCC(O)C4)c3)cnc21 +CCC(C(C)S(=O)(=O)CC)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CCCCCN(C(=O)c1ccc(Br)cc1)C(CC)c1nc2ccccc2c(=O)n1-c1ccccc1OC +O=C(NCCN1CCOCC1)c1nc(Nc2ccccc2Cl)nc(Nc2cc(C3CC3)n[nH]2)c1[N+](=O)[O-] +CN1CCC(NC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1 +O=C(CCc1ccccc1)c1ccccc1OCC(O)CNC(c1ccccc1)C1CCCCC1 +CN(CC(=O)Nc1nccc(Nc2ccc(S(N)(=O)=O)cc2)n1)C(=N)N +Cc1ccc2sc(S(=O)(=O)NC(=O)Nc3ncc(Br)s3)cc2c1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(CC(C)C)cc2CO)c1C +COCCCc1cc(CN(C(=O)C2CNCCC2(O)c2ccc(F)c(F)c2)C2CC2)cc(OCCOC)c1 +Cc1cc(-c2nc(-c3ccc(Cl)c(OC(F)F)c3)n3c2CCOCC3)cc(C)n1 +CCNCCS(=O)(=O)CCC1OCCC2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OCC12 +CC(CN1CCC(n2c(=O)[nH]c3cc(F)ccc32)CC1)NC(=O)c1ccc(F)cc1 +OCCNCCNc1nc2ccc(F)cc2c2[nH]c3ccccc3c12 +Fc1ccccc1-c1cc(-c2c[nH]nc2-c2ccccn2)ccn1 +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCCCN)C(=O)O)cc1 +CC1CN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2F)CC(C)C1(O)c1ccc(C(F)(F)F)cc1 +CC(C)Nc1cncc(-c2cnc3[nH]nc(-c4nc5c(-c6cncc(F)c6)cncc5[nH]4)c3c2)c1 +CCN1CCN(c2ccc(S(=O)(=O)N3CCCCC3)cc2NC(=O)Cc2c(Cl)cccc2Cl)CC1 +CC(Cc1cc2cc(-c3ncccc3C#N)ccc2nc1N)C(=O)NCCC(C)(C)C +CCCCOc1ccc(S(=O)(=O)N2CC(=NO)CC2C(=O)NO)cc1 +O=C(OC1(C2COCC(CC3CC3)N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CC2CC1CN2CCO +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)cc1-c1cc(F)cc(F)c1 +CCOC(O)=C1C(COCCNc2nc(N)n(C)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +COc1ccc(C(=CC=CC(=O)NC(CCCc2cccnc2)C(C)C)c2ccc(OC)cc2)cc1 +CC(C)(C)OC(=O)NC1CCCN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)C1 +Cc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)NCC3CCCC3)cc1)C2 +CN1CCN(c2cc(N3CCCCC3C(=O)NCCc3ccc(C#N)cc3)nc(C(F)(F)F)n2)CC1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(Cc1ccc(Br)cc1)C2 +O=C(NC(C(=O)N1CCCCC1)c1ccccc1)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1 +CCSCC1OC(n2cnc3c(N)nc(NN=CCC(C)C)nc32)C(O)C1O +O=C1OC2(CCN(CCc3c[nH]c4ccc(F)cc34)CC2)CN1Cc1ccc(Cl)cc1 +O=C(Nc1c[nH]nc1C(=O)Nc1ccc(CN2CCOCC2)cc1)c1ccccc1 +O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1ccc(-c2ccccc2Cl)s1 +Cc1ccc2c(c1)-c1nc(O)c(O)nc1C2(C)CC(=O)O +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCNCC3)cc12 +Cc1ccc(COc2ccc3nc(CC(C)(C)C(=O)O)n(Cc4ccc(Br)cc4)c3c2)nc1 +C1=CCOCc2cc(ccc2N2CCOCC2)Nc2nccc(n2)-c2cccc(c2)COC1 +C[S+]([O-])(CCN)=NP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1O +Oc1cccc(-c2cc(O)c3cc4c(cc3n2)OCO4)c1 +CNC(C)C(=O)NC1CCCC2CC3CCN(C(=O)OCc4ccccc4)CC3N2C1=O +Cc1cc(C)n2cc(C=Cc3nc(-c4cnccn4)cn3C)nc2n1 +O=C(c1nn(C2CCCN(CC3CCOC3)C2)c2c1CS(=O)(=O)c1c(F)cccc1-2)N1CCOCC1 +Cc1cc(Nc2cc(C(F)F)ccn2)nc(-c2ccc(C(C)(O)C3CCC(C(=O)OC(C)C)CC3)nc2)c1 +O=C(Nc1ccc2c(c1)C(N1CCN(C(=O)c3ccc4[nH]ccc4c3)CC1)c1ccccc1-2)c1ccco1 +Clc1ccccc1CNc1ncc(Br)c(Nc2cc(C3CC3)[nH]n2)n1 +COc1ccc(-c2ssc(=O)c2-c2cc(OC)c(OC)c(OC)c2)cc1 +CC(C)(NS(=O)(=O)c1cccc(OC2CCCC2)c1)c1ccc(Cn2ccc(=O)[nH]c2=O)cc1 +CNC(=O)c1cccc(-n2ccc3cnc(Nc4cc(OC)c(OC)c(OC)c4)nc32)c1 +O=S(=O)(Nc1cc(Cl)cnc1Oc1cccnn1)c1ccc(Cl)c(Cl)c1 +CC(NC(=O)C(=O)C(CCCCNC(=O)N1CCOCC1)NC(=O)OCC1(Cc2ccncc2)CCC1)c1ccccc1 +CC1CN(Cc2cncnc2)CC1c1nn2c(C3CCOCC3)ncc2c(=O)[nH]1 +COc1ccc(Cl)cc1-c1nc(CN(C)Cc2ccccc2)c[nH]1 +Cc1cccc(S(=O)(=O)Nc2ccc(C)n(CC(=O)NCCONC(=N)N)c2=O)c1 +COc1ccc(C2=NN(C3CCCCCC3)C(=O)C2(C)C)cc1OCc1ccccn1 +COc1cc(OCc2csc(-c3ccc(C(=O)N(C)CC4CC4)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(NCc1ccccc1)c1cc(C2CCNCC2COc2ccc3c(c2)OCO3)ccc1F +CCOC(=O)C1C2CCC(CC1c1ccc(-c3ccc(-c4ccccc4)n3C)cc1)N2 +COc1ccc(CCNC(=O)CN(c2cccc(Br)c2)S(=O)(=O)c2ccc(C)cc2)cc1OC +O=C(NCC(O)CO)c1cnn2ccc(N3CCCC3c3cc(F)ccc3C(F)(F)F)nc12 +Cc1c(Cc2c(F)cccc2F)nc(SCc2ccncc2)[nH]c1=O +CCn1c(C)c(C(c2ccc(F)cc2)n2ccnc2)c2ccccc21 +Cc1cc2c(C(C)C)c(O)c(O)c(C(=O)O)c2cc1Cc1ccc(C(F)(F)F)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccnc(-c2cncnc2)c1 +CN1CCN(c2ccc(Nc3ncc4ccc(-c5ccccc5)n4n3)cc2)CC1 +CC(COC(=O)NCCCn1ccnc1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(C2CC2C(=O)Nc2nc3ccc(-c4cc[nH]c(=O)c4)cc3s2)cc1 +CCCOc1cccc(O)c1-c1cc(C2CCCNC2)c(C#N)c(N)n1 +CN(C)CCN(C)c1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 +C[N+](C)(CCCCOc1c(Br)cc(Br)cc1Br)Cc1ccc([N+](=O)[O-])o1 +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCCCCCCC#N)c3C(C1)C2 +Cc1ccc(C(=O)NC2CC2)cc1Nc1nncc2c1cnn2-c1ccc(F)cc1F 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+Cc1ccccc1Cc1ccc(N2CC(C(F)(F)F)CC2CC(=O)O)cc1 +CN(C)CCOc1cc(-c2cn[nH]c2)ccc1NC(=O)C1Cc2cc(F)ccc2CN1 +CCCN1CCc2cc(N)cc3c2C1Cc1ccc(O)c(O)c1-3 +N=C(N)NCCCC(C=O)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)Cc1ccccc1 +COc1ccc(CC(=O)O)cc1C1=NCC(=O)N(Cc2ccc(F)c(F)c2)c2ccccc21 +Cc1cc(NC(=O)c2ccc3ccccc3c2)ccc1-c1ccc(OCC(C)(C)C(=O)O)nc1 +O=C(CCN1CCCC1)Nc1ccc2c(NC3CCCCCC3)c3ccc(NC(=O)CCN4CCCC4)cc3nc2c1 +CN(CCNCc1nccc2c1[nH]c1ccccc12)CCNCc1nccc2c1[nH]c1ccccc12 +CC1(C)CN=C(N2CCN(c3ncnc4sc(CC(F)(F)F)cc34)CC2)S1 +Clc1ccc(C2CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)cc1 +Cc1c(Cc2ccc(=O)n(Cc3ccc(F)cc3)c2)c2cc(F)ccc2n1CC(=O)O +COc1cccc(Cn2[nH]c(-c3ccccc3)c(Cc3ccc4c(c3)OCO4)c2=O)c1 +CCOC(=O)c1cnc2ccccc2c1Nc1ccc(C(C)=O)cc1 +CCCN(C)CC1CCCCN1C(=O)Cc1ccc2c(c1)CCCC2=O +CN1CCN(C2CCC(n3nc(-c4ccc(Nc5nc6cccc(C#N)c6o5)cc4)c4c(N)ncnc43)CC2)CC1 +CCC(c1nc2ccccc2c(=O)n1-c1ccccc1OC)N(CCc1ccccc1)C(=O)c1cccc(OC)c1 +COCCOc1cc2ncnc(Sc3nc(CC(=O)Nc4cccc(C(F)(F)F)c4)cs3)c2cc1OCCOC +CC1C2c3cc(Nc4ccccc4)ccc3CC(c3ccc(Nc4ccccc4)cc32)N1C 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+c1ccc2sc(NC3=NCC4(CN5CCC4CC5)O3)nc2c1 +CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(OC(=O)c3ccccc3)c3ccccc23)CC1 +CC(C)(C)C(N)C(=O)N1CC(c2cc(F)ccc2F)=CC1c1ccccc1 +COc1ccc(C2(Cc3ccccc3)CCNC2=O)cc1OC1CCCC1 +Nc1nc(N2CCN3CCCCC3C2)nc2nc(-c3ccco3)nn12 +O=C(NCC1CCc2n[nH]cc2C1)C1CCCN1C(=O)C(CC1CCCCC1)NS(=O)(=O)Cc1ccccc1 +O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1F +CS(=O)(=O)c1ccc(OC2CCCCC2)c(C(=O)N2CCN(c3ccc(C#N)cc3F)CC2)c1 +CC1(C)Cc2c(n(CC(N)C(=O)O)c(=O)[nH]c2=O)C1 +O=C(CCCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCc2ccccc2C1 +CC(=O)CSc1cc(F)c(F)cc1-c1ccc(OCc2cccc(C(=O)N3CCCC3C(=O)O)c2)cc1 +COc1cnc2c(NCc3nnc4ccc(-c5cc(F)cc(F)c5)nn34)ccnc2c1 +COc1ccc2ccc(=O)oc2c1C1=NN(S(=O)(=O)c2ccc(Cl)cc2)C(c2ccc(C(F)(F)F)cc2)C1 +CCOc1ccc(CC(NC(=O)c2cccc(C)c2)C(=O)NC(Cc2cccnc2)C(=O)NCc2ccc(CN)cc2)cc1 +CC1CC(C#N)C(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CO1 +COC(=O)c1sccc1S(=O)(=O)N1c2cc(Cl)ccc2NC(=O)C1C +COc1cccc(-n2cc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)cn2)c1 +CC(C)c1ccccc1N1CCN(CCCCCCC(=O)N2CCCC2C(N)=O)CC1 +CC(=NNC(=O)c1cc2ccccc2cc1O)c1cc2ccccc2[nH]1 +CCN(CC)C(=O)c1nn(C)c2nc(OCc3ccccn3)ccc12 +Cc1cccc(C2(CC(=O)N3CC(O)C3)C3CC4CC2CC(C3)C4O)c1 +COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(F)cc4)sc3n2)cc1 +Cc1nc2c3ccccc3nc(SCc3cn4cccnc4n3)n2n1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(F)cc(F)c2Oc2ccnc(N3CCOCC3)n2)cc1 +Cn1cc(-c2ccncc2)c(-c2ccc(OCc3cc(OCCOCCF)c4ccccc4n3)cc2)n1 +O=C(Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)C1CCSS1 +CN1CCN(CCCOc2ccc(-c3ccccc3)cc2)CC1 +NC(CC(=O)N1CCn2ncnc2C1)Cc1cc(F)c(F)cc1F +CCCCC(CC(=O)NN)C(=O)NC(C(=O)N(C)C)C(C)(C)C +O=C1CN(C(=O)n2sc3c(ccc[n+]3[O-])c2=O)CCN1 +NS(=O)(=O)c1ccc(-c2ccccc2-c2ccc(F)cc2)cc1 +CC(C)CCn1c(Cn2c(=O)n(C(C)C)c3ccccc32)nc2c(CO)cccc21 +CC(C)N1CCN(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 +CCCN(CCC)C(=O)C(=O)c1c(-c2ccc(C(=O)OC)cc2)[nH]c2ccccc12 +COc1cc(C(=O)N2CCC(n3c(=O)[nH]c4cc(F)ccc43)CC2)ccc1C +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1F +CN1CC(C(=O)Nc2ccc(Cl)nn2)CC2c3cc(C(C)(C)C)cc4[nH]cc(c34)CC21 +O=C(NCCc1cccc2ccccc12)C(CC#Cc1ccc(F)cc1F)NCP(=O)(O)O +CCCc1cc2c(=O)c(-c3csc(C)n3)coc2cc1O +CNC(=O)c1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +CC(=O)c1ccc(S(=O)(=O)NC(=O)c2ccc(Cl)cc2Cl)cc1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CC(C)OCC3C)ns2)n1 +CN(C)c1ccc(C(=C2C=CC(=[N+](C)C)C=C2)c2ccc(N(C)C)cc2)cc1 +COc1ccc(Oc2ncnc3cc(OC)c(OC)cc23)cc1OC +COc1ncc(Nc2nc3ccc(N4CCNCC4)cn3c2-c2nc(C)nc(N)n2)cc1F +COc1cccc(C(CC(=O)O)n2ccc3cc(OCCc4ccc5c(n4)NCCC5)ccc32)c1 +Clc1ccccc1CNc1cccc(-c2ccnc3[nH]c(C4CCNCC4)cc23)n1 +CNS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CCCN1CCN(C)CC1)CCCC3)C(=O)N2 +Cc1c[nH]c(NC(=O)c2nc(C)cc3cc[nH]c23)n1 +NC(=O)c1cc(NCc2cccnc2)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +COc1cnn(Cc2nc(NC(=O)NC(C)c3ccccc3)cc3[nH]nc(OC)c23)c1 +CN(C)C(=O)c1ccc(-c2ccc(-c3cc(NCc4cccnc4)n4ncc(Br)c4n3)cc2)cc1 +CCC(C)CNC(=O)N1CCCCC1C(=O)OCCCc1cccnc1 +Cc1ncc(C#Cc2c(C)ncnc2N(C)C(C)C)cc1NS(=O)(=O)c1ccc(F)cc1F +Cc1onc(C(=O)N2C3CCC2CC(Nc2cc(=O)n(C)c4nccnc24)C3)c1C +CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1ccccc1-c1ccccc1Cl +Cc1ccccc1Cn1c(=N)n(CC(O)c2ccc(Cl)c(Cl)c2)c2ccccc21 +CC(=O)N1CC2CN(CCOc3ccc(Oc4nc5ncccc5s4)cc3)CC2C1 +CCNCc1ccc2nc(C)c3nnc(-c4ccccc4Cl)n3c2c1 +CNc1nc(NCCCN(C)C)c2sc(-c3ccc(C#N)cc3)cc2n1 +c1ccc2c(c1)CNC(CN(Cc1ccc(CNCC3CCOCC3)cc1)C1CCCc3cccnc31)C2 +CCc1ccc(-n2cnc3c(sc4cccc(N(C)C)c43)c2=O)cc1 +COc1nc(OCc2cc(F)c(F)c(F)c2)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +COc1cccc(C(Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)C(C)NC(=O)C(F)(F)F)c1 +Cc1ccc(NC(=O)c2cnn(-c3ccccc3)c2C)c(C)c1 +Fc1ccc(C2CC(Oc3ccn4c(CC5CC5)nnc4c3C(F)(F)F)C2)cc1 +Oc1noc(C2CCNCC2)c1Cc1ccc2cccc(Br)c2c1 +CCOc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Cc1ccccc1 +O=C(c1ccc(-c2ccc3oc(CCN4CCCCCC4)cc3c2)cc1)N1CCOCC1 +O=C(Nc1cnccc1C(=O)N1CCC(O)C1)c1nc(C2CC2)ccc1Nc1cncnc1 +Cc1ccc(NC(=O)c2cccc(O)c2NC(=O)c2ccc(N3CCCN(C)CC3)cc2)cc1 +COc1cc(Nc2ncc3c(n2)CCN(C(=O)c2cccnc2)C3)cc(OC)c1 +CC1(C)CC(=O)c2ccc(C#Cc3ccccn3)nc2C1 +COc1ccc(NC(=O)c2ccc(C(=N)N(C)C)cc2F)c(C(=O)Nc2ccc(Cl)cn2)c1 +Cc1[nH]c2ccc(Cl)c(Cl)c2c(=O)c1-c1ccccc1 +COCC(NC(=O)Nc1cc2[nH]nc(OC3CCOCC3)c2c(C)n1)c1ccccc1 +CCC(=O)N1CCC(N(Cc2cc(Cl)ccc2Cl)c2ccc(C#N)c(Cl)c2)C1 +CC(C)NC(=O)c1ccc(-c2cnn3c(NCC4CCOCC4)nc(OC4CCCC4)nc23)cc1 +Cc1c(S(=O)(=O)c2ccccc2)c2cccnc2n1CCN(C)C +ClCCN(CCCl)CCOc1ccc(Nc2c3ccccc3nc3c(OCCN(CCCl)CCCl)cccc23)cc1 +O=C(OC1C[N+]2(Cc3cc(-c4ccccc4)on3)CCC1CC2)C1(C2=CC=CC2)CCCCCC1 +O=C(Nc1ccc(F)cc1)Nc1ccc(Nc2nc(-c3ccccc3)nc3c2nnn3Cc2ccccc2)cc1 +O=c1[nH]c(N2CCN(c3ccccc3Cl)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(n2cc(C3CC3)nn2)CC1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1cccnc1 +COc1ccc(CCNc2ncnc3c2[nH]c2ccccc23)cc1 +Nc1nc2c(ncn2C2COC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1 +Cc1nn(-c2ccccc2Cl)c2c1c1c(c3cccn32)C(=O)NC1=O +COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(c1ccc(N(C)CC3CCC(N(C)C)CC3)cc1)C(=O)C2 +COC(=O)c1cc2nccc(Oc3cccc(NC(=O)c4occc4C)c3)c2s1 +CC(C)(C)c1ccc(-c2ccc(CN3C(C(=O)NO)CCCS3(=O)=O)cc2)cc1 +CCCCCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(C(=O)N(C)C)cc(-c3ccccc3)n2)CC1 +CCCCCc1ccc(C#Cc2cn(CCC(COC(C)=O)COC(C)=O)c(=O)n(C(=O)c3ccccc3)c2=O)cc1 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+O=C1NC(=O)c2ccc(I)cc2C1=CNCc1ccc(-c2ccccn2)c(O)c1 +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2ccccc2)C(C(=O)OC)C1 +Oc1ccccc1-c1cc(Nc2ccc3[nH]ncc3c2)nc(N2CCOCC2)n1 +CCC(NC(C)=O)c1cc(Cl)ccc1C1CCN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(C(F)(F)F)cc2F)CC1 +CC1CN(c2ccc(F)c(NS(=O)(=O)c3ccc(-c4ccoc4)cc3)c2)CC(C)N1 +N#Cc1c(-c2ccccc2)nc(NNc2csc(Nc3ccc(S(N)(=O)=O)cc3)n2)[nH]c1=O +Cc1c2c(n3c1CCN(CC#N)c1cc(C(N)=O)c(Cl)cc1-3)CC(C)(C)CC2=O +CCCCC1CN(C(=O)c2cccc(C)c2C)CCN1CC(N)CS +Cc1nc(N2CCC(O)C2)ncc1-c1cc(C(F)(F)F)cc2[nH]ncc12 +CN(C)CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1C2COCC21 +CC1(CC(O)(Cn2ccc(=O)c3ccccc32)C(F)(F)F)CCCc2ccccc21 +CCCCNC(=O)C(CC(O)C(N)CC(C)(C)CC(=O)N1CC(NC(=O)OC)Cc2ccccc21)C(C)C +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4ccncc4)s3)c2)C(O)C(O)C1O +O=C(c1ccccc1)c1nc2ccccc2n2c(-c3ccc([N+](=O)[O-])cc3)nnc12 +CCCc1ccc(-c2ccc3c(n2)Oc2ccccc2C3C(C)(C)C(=O)Nc2nncs2)cc1 +Cn1c(=O)c2[nH]c(-c3ccc(S(C)(=O)=O)cc3)c(O)c2n(C)c1=O +O=C(O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2ccc(N3CCCCC3)cc2)CCCC1 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+CCOC(=O)C1=C(C)N=C(C)C(=C(O)OCC)C1c1ccccc1-n1ccnc1 +O=C(O)c1ccccc1-c1ccc(CCc2ncc(Cc3ccccc3)[nH]2)cc1 +CC(Oc1cc(-c2cnn(C3CCNCC3)c2)cnc1N)c1cc(F)ccc1Cl +Cc1nc(C(C)(C)NC(=O)c2cnc(C3CC3)c(-c3cccc(Cl)c3)n2)no1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2CCC3C)n1 +CN(CC1CCCO1)C(=O)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +COC1CCN(c2nc3ccc(NC(=O)c4c(C(=O)N5CCOCC5)cnn4C)cn3n2)C1 +CCOc1ccc(Br)cc1-c1cc(Nc2cccc(C#N)c2)nc(N)n1 +CCCCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O +Fc1ccc(CNCCCNc2ccnc3cc(Cl)ccc23)cc1 +CC(=O)C(C)N(CC(F)(F)F)c1ccc2[nH]c(=O)cc(C(F)(F)F)c2c1 +CC(=O)N1CCC(n2nc(C(N)=O)c3c2-c2nc(NC4CCCC4)ncc2CC3)CC1 +CNC(=O)C=C1COc2c1ccc(OS(=O)(=O)CCC(F)(F)F)c2C +O=C(NCC(NS(=O)(=O)c1ccc(C(F)(F)F)cc1)C(=O)O)c1ccc2c(cnn2CCCNc2ncc[nH]2)c1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc(-c4cccs4)cn3)C12 +CCCOc1ccc(-c2ccc(C(=O)NCC(C)(C)C)cc2C(=O)O)c(C(=O)Nc2ccc3c(N)nccc3c2)n1 +CN(C)C(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1 +CC(=O)N1CCC(CN(C)C(=O)c2ccc(S(=O)(=O)Nc3ccccc3)cc2)CC1 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+O=C(NC1c2ccccc2CC1O)C(SCc1ccccc1)C(O)C(O)C(SCc1ccccc1)C(=O)NC1c2ccccc2CC1O +O=C(c1ccc(F)cc1)c1oc2cc(O)ccc2c1-c1cccc2ccccc12 +Nc1nccc(-c2cc3c([nH]2)C(CCC(F)(F)F)CNC3=O)n1 +COc1ccc(CC(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)C(=O)O)cc1 +COC(=O)C1CCc2cc(Nc3nc(C)cc(Nc4cc(C5CC5)n[nH]4)n3)ccc2N1 +CC(C)N1CCN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCC3)CNC5=O)nc2)CC1 +O=C1c2ccccc2C(=O)C1CC#CCN1CCCCCCC1 +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(Cc3cccnc3)C2=O)cc1 +CC(O)CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1 +O=C(NO)c1cnc(NC2(c3ccccc3)CCCC2)nc1 +O=C(Nc1cc2c(=O)n(O)c(=O)[nH]c2cc1Cl)c1ccccc1 +CCC(CO)Nc1nc(NCc2ccc(C)s2)c2ncn(C(C)C)c2n1 +O=C(NCC(c1cnc(C2CC2)nc1)N1CCC(F)(F)CC1)c1c(F)cccc1Cl +O=C(O)c1cc(F)cc(C(=O)C=Cc2ccc(OCc3ccc4ccccc4n3)cc2)c1O +Cc1c(C(=O)OC(C)C(=O)N(C)Cc2ccccc2)oc2ccccc12 +Cc1ccc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1C +O=C(OCC1C(O)C(O)C(O)C2NC(=O)c3c(cc4c(c3O)OCO4)C12)c1ccccc1 +CC(C)(C)N(CCC(=O)c1ccc(Cl)cc1)Cc1ccccc1 +Cc1cccc2[nH]nc(NCC3CCC(NC(=O)c4cc(C(F)(F)F)ccc4Cl)CC3)c12 +O=C(CNCC1CCCO1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 +CC(C)CNc1nc(-c2cccc3ncccc23)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(NC(=O)c3ccc(C)c(OC)c3)cc2)cc(OC)c1 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(CNC5CCCC5)CC4)cc2)CC3)cc1 +CCOc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1Cc1ccccc1)CC2 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CCCNC4)ncc23)ccn1 +CCN(C(=O)CCCOc1cc(-c2cccnc2)nn1-c1ccc(Cl)c(Cl)c1)C(CC(N)=O)c1ccc(C)cc1 +COc1cc(OCc2cccc(-c3cnc(OC)cc3C)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Cc1[nH]c(-c2cccnc2)nc1-c1ccc(Cl)cc1 +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2cc3ccccc3[nH]2)c1 +COC1(C#CC(O)(c2ccccc2)C2CCCCCC2)CN2CCC1CC2 +CCOC(=O)c1ccc(NC(=O)NCc2ccn(-c3cc4nc(O)c(O)nc4cc3C(F)(F)F)c2)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCC(CO)C2)c(-c2ccc(CF)nc2)c1 +CN(C)CC(O)COc1ccc(Nc2nccc(Nc3cc(C(F)(F)F)ccc3F)n2)cc1 +CNc1nc(NC2(C#N)CCC(C)CC2)nc(-n2cncn2)n1 +COc1cccc(C2(OCC(F)(F)F)SC=C(C)n3c2noc3=O)c1 +Oc1cncc(-c2nc(N3CCOCC3)c3ncn(C4CCNCC4)c3n2)c1 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+O=C(NCC(NS(=O)(=O)c1ccc2ccccc2c1)C(=O)O)c1ccc2c(cnn2CCCNc2ncc[nH]2)c1 +CCC1(CCCCN2CCN(c3ccccc3Cl)CC2)C(=O)Nc2ccccc21 +O=C(NC1CCCc2cc(CN3CCCCC3)ccc21)C(O)C(O)CS(=O)(=O)c1ccccc1C(F)(F)F +Fc1ccc(-n2c3c(c4cc(F)ccc42)CN(CCc2ccncc2)CC3)cc1 +CC(C)C(=O)NCc1ccc(Cl)c(-c2nc3cc(-c4ccc(C(F)(F)F)cc4)ncc3c(=O)[nH]2)c1 +Cc1nn(C)c2ncc(C(N)=O)c(Nc3ccccc3)c12 +Cc1c(Nc2nc3c(Br)c(Br)c(Br)c(Br)c3[nH]2)cccc1-c1nncn1C +N#Cc1ccc(OCC2CCN(Cc3ccccc3Br)CC2)cc1 +CCCCOc1cc(C=CC(=O)O)ccc1OC(=O)CCc1ccccc1 +CCN(SC(=S)N1CCOCC1)C1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(Cn5cnc6cccnc65)C4)cc23)ccn1 +N#Cc1c(Oc2cccc(NC(=O)Nc3ccccc3C(F)(F)F)c2)ccc2nc(NC(=O)C3CC3)sc12 +COc1cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncccn5)ccc43)cc2F)ccc1Cl +CCc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1Br +Cn1c(C(=O)Nc2ccccc2CCc2ccc(OC3CCNCC3)cc2)cc2sccc21 +CC(C)CC(NC(=O)CC(NCc1cccnc1)c1cccc(Cl)c1)B(O)O +c1ccc2oc(Oc3ccc(OCCN4CCCC4)cc3)nc2c1 +CNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3sccc3n2)cc1 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+O=C(NC1CCC(C(=O)Nc2ccc(-c3ccccc3F)cc2)CC1)c1ccon1 +CCCCc1nnc(SCc2ccc(Cl)cc2)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +CS(=O)(=O)Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1 +CN(C)C1CN(C2COc3cccc(F)c32)CC1c1cn(C)c2ccccc12 +CON(C)C(=O)c1cc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)ccc1F +Cc1n[nH]c(C(C#N)=Cc2ccc([N+](=O)[O-])o2)n1 +CC(NS(=O)(=O)c1cccc(-c2ccccc2)c1)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1 +CCc1nn(CCN)c(CC)c1Oc1cc(Cl)cc(C#N)c1 +O=C(Nc1nnc(-c2cccs2)o1)c1cccc(Oc2ccccc2)c1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC(F)F)CC3)c(OC)c2)c1C#Cc1ccc(N)nc1 +CC(C)(C)OC(=O)NNc1ccc(C(F)(F)F)cc1C(=O)N=c1sc(C(C)(C)C)cn1CC1CCCO1 +CC(C)CC(=CC(=O)Nc1ccc2c(c1)OCCO2)c1ccc(C(C)(C)C)cc1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4cnccn4)nc31)C(O)C2O +Cc1ccc(Cl)c2c1[nH]c1nc3nnc(Cc4ccc(O)cc4)n3nc12 +CC(C)(C)c1nnc2n1CCN(C(=O)c1cccc(C(F)(F)F)c1Cl)C2 +CCc1ncnc(-c2ccc(C(=O)NC3CCN(C)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +O=C1C(=Cc2ccc(Cl)cc2)CCCC1=Cc1ccc(Cl)cc1 +CN(CCc1ccccc1)C1CCN(c2nc3ccccc3n2Cc2ccc(F)cc2)CC1 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+Clc1ccc(-c2nn(-c3ccccc3)c3c2CCCC3)cc1 +O=C(O)Cc1ccc2oc(-c3ccc(C=CC(=O)Nc4ccc(Cl)c(Cl)c4)cc3F)nc2c1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccc(C(F)(F)F)cc4)oc3C)ccc21 +COc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(C2=NCCS2)cc1 +Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(Br)c(Cl)c1 +CCN(CC)c1nc(C)nc2c(-c3cnc(OC)cc3C)c(C)nn12 +[O-][n+]1nc2c(-c3ccc[nH]3)cnn2c2cc(-c3ccsc3)ccc21 +O=C(O)c1ccc(NC(=O)C2NC3(CCCCC3)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)o1 +O=P(O)(O)OC1COCC1OC1OC(CO)C(OP(=O)(O)O)C(OP(=O)(O)O)C1O +COC(=O)C(C)NC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)CC(C)C)C(C)C +[H]C([H])([H])Oc1cc(F)cc(N(CCN)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CN(C)NC(=N)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)cc1 +CCCN(CC1CC1)c1cc(C)nc(C(=O)c2c(OC)cc(OC)cc2OC)n1 +Cc1ccccc1CN1CCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C1 +O=C(Nc1ccc(-c2nc(N3CCOCC3)c3ncccc3n2)cc1)Nc1cccnc1 +CC(C)Nc1nc(S(=O)(=O)c2ccc(N)nc2)ccc1-c1ccc(C(C)(O)C(F)(F)F)cn1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCCN(Cc2cccc3c2OCC3)C1 +Cc1csc(N(C)C2CCc3c(c4cc(F)ccc4n3CC(=O)O)C2)n1 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+Cc1nc(C2CC(C(=O)C=Cc3cnc4c(c3)CCC(=O)N4)C2)no1 +COc1ccc(-n2nc(CC(C(=O)O)c3ccc(C)cc3)cc2-c2ccc(C)cc2)cc1 +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(Cc2cccs2)CC1 +Cc1cc(C)c2c(c1NC(=O)C(C)(C)CCCCCOc1ccc(Cl)cc1)OCCC2=O +CCN(CC)CCNC(=O)c1ccc2cc(Nc3nc(C)cc(Nc4cc(C5CC5)n[nH]4)n3)ccc2c1 +CON(C)C(=O)C=CC1(C)C(C(=O)O)N2C(=O)CC2S1(=O)=O +Cc1ccc(Cn2ccnc2C=NNc2nc(NC3CCN(C)CC3)c3ccccc3n2)cc1 +CC(CO)Nc1nc(Nc2ccc(S(C)(=O)=NS(=O)(=O)CC[Si](C)(C)C)cc2)ncc1Br +Cc1cc(-c2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)ccc1C(=O)O +Fc1cc(Nc2cc(Nc3ccccc3)ncn2)ccc1Oc1ccncc1-c1cccnc1 +Cc1cccnc1-c1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 +Cc1n[nH]c2c1C(c1ccc(F)c(F)c1)c1c([nH]c(=O)[nH]c1=O)O2 +CC(C)Nc1ncc(Cl)cc1C(=O)NC1CCN(Cc2ccc3c(c2)OCO3)CC1 +CC(N=C(S)Nc1ccc(S(N)(=O)=O)cc1)C(=O)NC(Cc1ccccc1)C(=O)O +Cc1cc(-c2n[nH]c3ccc(C(=O)NN4CCCC4CCc4ccccc4)cc23)ccn1 +Cc1csc(N2CCc3cc(S(=O)(=O)Nc4ccccc4)ccc32)n1 +COc1ccc(Cc2nc(O)c3c(C)nc(C(CCCc4ccccc4)C(C)O)n3n2)cc1OC +CS(=O)(=O)N1CCC(C(CCC(=O)Nc2ccc(F)c(F)c2)c2ccc(-c3cccc(C#N)c3)cc2)CC1 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+CCCCCCN(C(=O)Nc1ccc(N(C)C)cc1)C1Cc2ccc(SC(C)(C)C(=O)O)cc2C1 +NC(Cc1ccccc1)C(=O)NC(=S)NCCc1ccc(S(N)(=O)=O)cc1 +CN1CCN(CC(O)Cn2c3ccccc3c3ccccc32)S1(=O)=O +CCCNCc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1 +COc1cc(Cc2c(-c3ccc(OCCN4CCCC4)nc3)sc3cc(O)ccc23)ccc1CN1CCCC1 +COCCNCCC(=O)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 +N#Cc1c(-c2ccc(C(F)(F)F)cc2)cc(NC2CCNCC2)n2c1nc1cc(Cl)cc(Cl)c12 +OC1CCC(Nc2ncc3nc(Nc4c(F)cc(F)cc4F)n(C4CCOC4)c3n2)CC1 +CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3cnc(Cl)c4ccccc34)cc12 +Cn1cc(-c2ccc3ncc(N(CCN)c4cc(F)cc(OCCO)c4)nc3c2)cn1 +CN(C)CCN(c1ccncc1)c1ccc(-c2ccc3c(C(N)=O)nn(-c4ccc5onc(N)c5c4)c3c2F)c(F)c1 +CN1CCC23c4c5ccc(O)c4OC2c2[nH]c4ccccc4c2CC3(O)C1C5 +Cc1cc(C)cc(C(=O)N2CCC(NC(=O)c3ccnc4ccccc34)CC2Cc2ccccc2)c1 +NC(=O)C(O)CC1CCc2sc3ncnc(OC4CCC(N5CCOCC5)CC4)c3c21 +Cc1n(C(C)c2ccc3oc4ccccc4c3c2)cc[n+]1CC(=O)c1ccc2ccccc2c1 +OB(O)c1ccccc1OCc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1 +COc1ccc(C=CC(=O)N2CC3CC34C2=CC(=O)c2[nH]c(C)c(Br)c24)cc1 +COc1cnc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)nc1OC +CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)C(=O)N4CCc5ccccc5C4)cc3)cc2n(CCC)c1=O +CC(C)NC(=O)N1CCCc2cc(OCCCN3CCCCC3)ccc2C1 +Nc1nc(OCCc2c[nH]c3ccc(I)cc23)nc2c1ncn2C1OC(CO)C(O)C1O +CCN(CC)CCCN1CCC2(N3CCN(C)CC3)CC(c3ccccc3)C1C(c1ccccc1)C2 +CCN(CC)CCNc1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(C(C)C)no2)n1 +CC(C)N1CCN(CCN2CCN(C3CC(c4ccc(Cl)cc4)c4cc(Cl)ccc43)CC2)C1=O +CC(C)N(CC(=O)Nc1cc(C(C)(C)C)nn1-c1ccc(Cl)c(Cl)c1)C(=O)c1ccc(Cl)c(Cl)c1 +O=C(NC1CN2CCC1CC2)c1cc2cccc(Br)c2o1 +C#Cc1ccc2c(c1)C(=O)N(C(C(=O)O)c1ccc(Cl)cc1)C(c1ccc(Cl)cc1)C(=O)N2 +CN1CCN(CCOc2ccc(-c3cccc(N)n3)c3ccccc23)CC1 +COc1ccc(C2Nc3ccc([N+](=O)[O-])cc3C3C=CCC32)cc1[N+](=O)[O-] +CC1CCC(Cn2c(N3CCOCC3c3ccccc3F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CCCCc1ccc(-c2[nH]c3ccc(CC)cc3c2C=O)cc1 +COc1cccc(-c2nc(CCOc3ccc4c(c3)CCC4CC(=O)O)c(C)s2)c1 +O=S(=O)(Nc1ccc(Oc2ccc(Cl)cc2O)c(Cl)c1)c1ccccc1 +Cc1nnc2n1-c1sc(C#CCN3Cc4cccc5cccc(c45)C3=O)cc1C(c1ccccc1Cl)=NC2 +O=C(NC(=O)c1ccccc1C(F)(F)F)NC1c2ccccc2-c2ccccc21 +COc1ccccc1Oc1cccc(CN2CCC(NC(=O)C3(c4ccccc4)CCNCC3)(C(=O)O)CC2)c1 +O=C(Nc1cc(Cl)ccc1N1CCC(O)C1)c1cnn2cccnc12 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(-c2cscn2)c1 +COC(=O)NC(C)CNc1nccc(-c2cn(C(C)C)nc2-c2cc(F)cc(NS(=O)(=O)C3CC3)c2F)n1 +NCC1CCC(Nc2cc(-c3cncc(NCC4CCOCC4)n3)c(Cl)cn2)CC1 +COc1ccc(CN(CCCOc2cccc(CC(N)=O)c2)CC(c2ccccc2)c2ccccc2)c(F)c1 +O=C1CCC(c2ccc(OCCCN3CCCCC3)cc2)CC1 +COc1cc(N)c(Cl)cc1C(=O)NC1CC2CCC(C1)N2Cc1ccco1 +CNc1nc(C)c(-c2ccnc(Nc3cccc([N+](=O)[O-])c3)n2)s1 +Cc1cc2c(cc1C(=O)c1ccc(C(=O)O)s1)C(C)(C)CCC2(C)C +O=C(O)c1ccc(CCCN2C(=O)CCC2CCC(O)Cc2cccc(C(F)(F)F)c2)cc1 +CC(Nc1nccc(C2CCCN(CCc3c[nH]c4ccccc34)C2)n1)C1CC1 +N#CC(COCc1cccc(C(=O)O)c1)NC(=O)C(Cc1ccccc1)Nc1ccccc1 +CC(O)(C#Cc1ccc2c(c1)-n1nc(C(N)=O)cc1C(F)(F)CO2)CF +CC(C)(N)C(=O)NC(COCc1cccc(Cl)c1Cl)c1nnnn1CCOC(=O)NCCCCO +O=C(CCOCCc1ccccc1)NCCNCCc1ccc(O)c2nc(O)sc12 +O=C(c1nc(-c2ccccc2Cl)c2ccccc2n1)N1CCCCC1 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+Cn1c(OC2CCN(Cc3ccccc3)CC2)nc(-c2ccncn2)cc1=O +CC1CC(N)CC(c2ccncc2NC(=O)c2csc(-c3c(F)cc(O)cc3F)n2)C1 +COc1cc(Nc2ccc(S(=O)(=O)NCC3CCCO3)c(F)c2)cc(OC)c1 +CN1C(=O)NS(=O)(=O)c2cc(-c3cnc(N4CCOCC4)c4nc(C=Cc5ccc6ccccc6n5)cn34)ccc21 +CSc1ccc(C2CN(C)Cc3cc(OCCCN4CCOCC4)ccc32)cc1 +Cc1nc(NCc2ccc(F)c(F)c2)nc(-n2ccnc2C)c1[N+](=O)[O-] +C=CC(=O)N1CCC2(CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)CC1 +O=C(CCCCCN1CCN(c2nc3ccccc3[nH]2)CC1)c1ccccc1O +O=C1NC(=O)c2c1c1c3ccccc3ccc1c1c2c2cccc3c2n1C(CO)CC3 +O=C1OC2(CCC(CNc3cnn(-c4ccccc4F)c3)CC2)CN1c1cnccn1 +CCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(C(N)=O)cc2)c([N+](=O)[O-])c1 +O=C(CSc1nnccc1-c1cccc2ccccc12)Nc1ccccc1F +CN(C)CCOc1cc(C(N)=O)c2ncnc(NCc3cccc(NC(=O)c4ccnc(N5CCCC5)c4)c3)c2c1 +Cn1ccc2c(CCNS(=O)(=O)c3ccc(C=CC(=O)NO)cc3)cccc21 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cc(Cl)c(F)cc3F)ccc2[nH]1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cnn(CCN4CCOCC4)c3)cc2s1)S(=O)(=O)CC1CC1 +CCN(c1nc(C)nc(N(CCOC)CC2CC2)n1)c1c(C)cc(C)cc1C +CCOc1ccc(C#Cc2ccc(CC(C)NC(=O)N(C)CC)cc2)cc1 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+COc1ccc(-c2cc(NC(=O)Nc3ccccn3)cc(OC)c2OC)cn1 +O=C(Nc1ncns1)C1CC(F)CN1c1nc(Nc2cc(C3CC3)n[nH]2)c2cccn2n1 +CCN1CCC(c2ccc(-c3cc4ncn(C)c(=O)c4c(NC4CCOC4)n3)cc2)CC1 +CC(C)(C)n1c(-c2cc(F)cnc2-n2cncn2)nc2cc(-c3cnc(N)nc3)ccc21 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(-n4cnc5cc(C(=O)NCCCN6CCCC6)ccc54)nc23)N1 +C=CCN1C(=O)C(=CNc2ccc(Cc3ccncc3)cc2)C(=O)NC1=S +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCNC1=O +C=CS(=O)(=O)Nc1cccc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCCC(O)C2)c(-c2ccn[nH]2)c1 +CN(CCOc1ccc(-c2ccc(Cl)cc2)cc1)CCN1CCN(c2ccncc2)C1=O +Nc1ncnc(C#Cc2ccccn2)c1-c1ccc(Cl)cc1 +N#Cc1nccc2nc(NC3CC3)c(N3CCN(Cc4ccc(F)cc4F)CC3)nc12 +O=S(=O)(O)OCC1CCC2(CC1)OOC1(O2)C2CC3CC(C2)CC1C3 +O=C(c1cnc2ccc(-c3ccc(O)c(Cl)c3)cc2c1N1CCN(CCN2CCCC2)CC1)C1CC1 +Cc1cnc(NCC(F)(F)c2ccccc2)c(=O)n1CC(=O)NCc1ncccc1F +CNCCCOc1cc(F)c(C2=C(NCC(F)(F)F)N3N=CNC3N=C2Cl)c(F)c1 +CC(C)Oc1ccc(Cl)c(C2CC(=O)C(Sc3cc(O)ccc3C#N)=C(O)C2)c1Cl +Cc1n[nH]c(C)c1-c1cc(C(=O)c2nc3nc(N4CCNCC4)ccc3[nH]2)ccn1 +COc1cc(-c2nc(NCCc3ccccc3)ncc2C(=O)NCCOc2ccccc2)cc(OC)c1OC +O=C(O)CC(NC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1)c1cccnc1 +FC(F)(F)c1ccccc1-c1cc(Br)c2[nH]c(C3=NOC4(CCCCC4)C3)nc2c1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1cc(C(F)(F)F)nn1-c1ccccc1 +CCCON=C(c1ccc(C(=O)O)cc1)c1cc2c(cc1C)C(C)(C)CCC2(C)C +N#CCN1C(=O)N(Cc2cc(F)cc(F)c2)S(=O)(=O)c2cscc21 +NC1CCN(c2ncc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(F)c(O)c(Cl)c5)cc34)cn2)C1 +NP(=O)(OCCOc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)N(CCCl)CCCl +COc1cc2nc(N3CCN(C(=O)C4COc5ccc(S(=O)(=O)N(C)C)cc5O4)CC3)nc(N)c2cc1OC +O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1cnc(N2CCC(C(=O)O)CC2)c(Br)c1 +Fc1ccc(Nc2ncnc3ccc(-c4cncs4)cc23)cc1Cl +Fc1ccc(C(c2nnnn2Cc2ccccc2)N2CCN(C3CCC3)CC2)cc1 +CCCc1ncccc1CN(CCCOc1ccc2c(c1)N(C)C(=O)C(C)(C)C(=O)N2CC)CCn1ccc2oc(C)cc2c1=O +CN1C(=O)CCc2cc(-c3cncc(COc4ccc(Cl)cn4)c3)ccc21 +CCNC(=O)Cc1ccc(Cl)c(CN(C(=O)C2CNCCC2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1 +Cc1ccc2oc(=O)c(-c3cccc(OC(=O)c4ccccc4)c3)cc2c1 +O=C(NC1c2ccccc2CC1O)C(Cc1ccccc1)CC(O)CN1C(=O)N(Cc2ccncc2)CC1Cc1ccccc1 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+O=C(Nc1cc(F)c(CC(=O)N2CC(F)CC2COC2CCC(C(=O)O)CC2)cc1Cl)c1nccc2ccccc12 +O=C1Nc2cccc3c2C1(CCCCN1CC=C(c2ccccc2)CC1)CCC3 +CCc1c2ccccc2[n+](C)c2c1[nH]c1ccccc12 +O=C(Nc1ccc(CC(NC(=O)C23CC4CC(CC(C4)C2)C3)C(=O)O)cc1)c1ccnc2ccccc12 +CC(C)(C)c1cc(C#N)cc2nc(-c3ccc(C(=O)NCC4CCN(c5ccc(C(F)(F)F)cn5)CC4)cc3)oc12 +O=C(NCc1cccs1)c1cc(C(=O)c2c(Cl)cccc2Cl)c[nH]1 +COc1cc(CCNCc2ccc(F)cc2F)ccc1NC(=O)Nc1cnc(C#N)cn1 +COc1cc(CNC(=S)NCc2ccc(C(C)(C)C)cc2)c(I)cc1O +Cc1ccc2c(CC(=O)O)cn(-c3ccc(C(F)(F)F)cc3CN(CC3CC3)C(=O)C3CC3)c2n1 +Cc1ccccc1-n1nc(-c2c(-c3ccc(F)cc3)nn3c2NCC(CO)C3)ccc1=O +CC1(C)CC(CCNc2ccc(OC(F)(F)F)cc2)(c2ccccc2)CCO1 +CNc1nc2nc(SCc3cccc(F)c3F)nc(NC(C)CO)c2s1 +O=C1c2c(O)cccc2Cc2cc(Cc3ccc(O)cc3)cc(O)c21 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)NC(CCC(=O)O)C(N)=O)cc1 +NS(=O)(=O)c1cc(S(=O)(=O)c2cccc(O)c2)cs1 +CC(C)N1CCN(c2cc(N3CCOCC3)cn3c(=O)c(O)c(-c4ncc(Cc5ccc(F)cc5)[nH]4)nc23)C1=O +Cc1ccc(C(=O)O)c(Oc2nc(Oc3cc(-c4cccc(CN)c4)ccc3N)c(F)cc2F)c1 +Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1COc1ccc2c(c1)OCC2CC(=O)O 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+CCCCCCCN(CCCCCSc1nc(C2CCCCC2)c(C2CCCCC2)[nH]1)C(=O)Nc1ccc(F)cc1F +CCOC(=O)c1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 +CC(c1ccc(O)cc1)C(O)C=CC1C2CCC(O2)C1CC=CCCCC(=O)O +CC(C)CNC(=O)CC1Sc2sc(S(N)(=O)=O)cc2NC1=O +Cc1nc(NC2COCC2C)nc(-n2ccnc2C)c1[N+](=O)[O-] +COc1ccc2c(c1)c(CC(=O)NCc1ccncc1)c(C)n2C(=O)c1ccc(Cl)cc1 +COc1ccc2c(c1)CNC(C(=O)N1CCCC1C#N)C2 +O=C1OC2(CCN(C(=O)Nc3cc(-c4ccccc4)n[nH]3)CC2)c2ccccc21 +CNC(=O)CN1CCN(c2cc(C)c3nc(-c4c(NCC(O)c5cccc(Cl)c5)cc[nH]c4=O)[nH]c3c2)CC1 +CN(CCN(C)c1nc2ccc(Br)cc2s1)c1nc2ccc(Br)cc2s1 +CCCC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)s1)C(=O)NC(CC(=O)O)C(=O)O +CN(C)CC(OC(=O)N1Cc2c(n[nH]c2Nc2ccnc(C(F)(F)F)n2)C1(C)C)c1ccccc1 +CNC(=O)c1cc2c(Oc3ccc(C(=O)NCCN4CCOCC4)cc3)cncc2s1 +Cc1c(-c2cnc(N)c(-c3ccc(C(=O)NC(CO)c4cccc(C(F)F)c4)c(F)c3)c2)cnn1C(F)F +CN(CCCNCc1ccc(C(=O)O)cc1)CC(=O)Nc1ccc(Oc2ccccc2)cc1 +O=C(c1cccnc1)N1CCC(c2nc(-c3cnc(-c4ccccc4)nc3)c[nH]2)CC1 +Cc1cccc(C)c1C1CCN(CCC(=O)N2c3ccccc3CC2C(=O)N(C)C)CC1 +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)Nc3ccccc3O)nc12 +Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OC(C)C(F)(F)F)c(C3CCC3)cn2)no1 +CC12CCC(O)CC1CCC1C2=C(O)C(=O)C2(C)C(c3ccc(=O)oc3)CCC12O +CCCS(=O)(=O)c1ccc2cc(-c3cccc(-c4ccccc4)c3)[nH]c2c1 +O=C(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)c1ccccc1 +CCN(CC)c1ccc2nc(-c3ccccc3C(F)(F)F)[nH]c(=O)c2c1 +Oc1ccc(CC2Sc3cc(O)ccc3OC2c2ccc(OCCN3CCCCC3)cc2)cc1 +N#Cc1ccc(Nc2nc(C#N)nc(NC3CCCCC3)n2)cc1 +COc1ccc(C(=O)Nc2ccc(-c3ccc(OC4CCN(C)CC4)cc3)cc2)cc1-c1cccc(Cl)c1 +CCCN(CC1CC1)c1nc(C)nc2c1sc(=S)n2-c1c(C)cc(C)cc1C +O=C(CCCCN1CCC(c2ccccc2)CC1)c1nc2ccccc2s1 +CCOP1(=O)N=C(C2=C(O)C(C(C)(C)C)N(CCC(C)C)C2=O)Nc2ccc(NS(C)(=O)=O)cc21 +Cc1cc(F)ccc1Oc1cc(C(C)(C)C)ccc1C(=O)Nc1ccc(C(=O)O)nc1 +CCCCN1CC2CCC(OCc3ccccc3)C1CN2Cc1ccccc1 +COc1ccc2c(c1)CCC(CCN1CCN(c3ccccc3)CC1)C2 +Cc1cccc(C#Cc2ccc(N3CC(C)(C)N(C)C3=O)nn2)c1 +N=C(N)c1cc2[nH]c(-c3cccc(OCC4CCCNC4)c3O)nc2cc1F +COc1ncc(C(=O)NC2(C(=O)NC(C)c3ncc(-c4cc(Cl)cc(F)c4-c4noc(C)n4)cc3F)COC2)cn1 +Cc1cc(C)n(Cc2ccc(Cn3cc(C(=O)NCc4c(C)cc(N)nc4C)cn3)cc2)n1 +Cc1cccc2c1N(C1CCN(S(=O)(=O)c3cccc4ccccc34)CC1)C(=O)OC2 +COc1ccc(CNC(=O)CCCCC=CCCCCCCCCCCCCC(=O)NCc2ccc(OC)c(O)c2)cc1O +CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC(C)(O)C3)c(Cc3ccccc3C(F)(F)F)sc21 +CCC(=NNC(N)=S)c1cccc([N+](=O)[O-])c1 +CCC(C)Oc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc2[nH]cnc12 +CN1CCCN(CCCOc2ccc(-c3nc4cc(C(C)(C)C)ccc4[nH]3)cc2Cl)CC1 +COc1ccc(-c2nc3c(c(=O)[nH]2)COCC3)cc1 +CCCCc1nc2ccc(C3CC4CCC(C)(C)N4O3)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(C(F)(F)F)n2)c2c(N)ncnc21 +CC(=O)c1ccc(N2CCN(Cc3cccnc3)CC2)cc1 +O=C(NCc1ccc(F)c(F)c1)c1cc2cccc(O)c2n(O)c1=O +COc1ccc(N2CCN(C(=O)C3CCCCC3C(=O)NCC#N)CC2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccccc1)c1ccc(CNS(C)(=O)=O)c(F)c1 +CCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OCC(C)C(=O)OC)S(=O)(=O)c1ccc(OC)cc1 +O=S(=O)(NCC(c1ccc(C(F)(F)F)cc1)N1CCN(CC(O)COc2ccc(F)cc2)CC1)c1ccccc1Cl +CN1CCC23c4c5ccc(O)c4OC2C(O)C=CC3C1C5 +CC(=NNC(=O)c1ccccc1)C(Cl)=NNc1ccc(S(N)(=O)=O)cc1 +O=C(Nc1ccc(F)cc1F)NC(Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1 +O=C(O)CCC(=O)Nc1cc(CO)cc(Nc2c3ccccc3nc3ccccc23)c1 +O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(N2CCc3c(cnc4ccccc34)C2)c1 +COc1ccc(NC(=O)Nc2cccc(C=CC(=O)CC3OC(CO)C(O)C(O)C3O)c2)c([N+](=O)[O-])c1 +COc1cccc(-c2cn(Cc3c(F)cccc3S(=O)(=O)C(C)C)c(=O)n(CC(N)c3ccccc3)c2=O)c1F +N=C(N)c1ccc(CNC(=O)CN2C(=O)C(NS(=O)(=O)Cc3ccccc3)CSc3ccccc32)cc1 +CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1NC1CCC(C)(O)CC1 +Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3cnc4ncccn34)n2)cc1 +CNC(=O)Cn1cc(-c2cnc3ccc(N(CCO)c4cc(OC)cc(OC)c4)cc3n2)cn1 +COc1ccc(C(=O)Nc2cc(Br)cc3c(=O)cc(C(=O)O)oc23)cn1 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCc3c(C(=O)O)nc(C)n3-c3ccccc32)n1 +COc1cc(OC)c(-c2cc3ccccc3s2)cc1C=CC(=O)c1ccc(C(=O)O)cc1 +O=c1[nH]cnc2c(C3OC(CO)C(O)C3O)n[nH]c12 +CCN(CC)CCNc1ccc(CNS(C)(=O)=O)c2sc3ccc(O)cc3c(=O)c12 +Cc1cc(F)c(F)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CC(C)N(C(=O)c1ccc2ccccc2c1)C1CCNC1 +CCN(CC)CCCNC(=O)c1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(-c3ccccc3)no2)n1 +CCCCCCCCCCCNC(=O)C(N)CCC(=O)NC(CCCC(N)C(=O)O)C(=O)O +COc1cccc2c1CCCC2CN(C)CCc1ccc2ccoc2c1 +CC(C)(C)C(=O)Oc1coc(CSc2nc3cc(C(=O)O)ccc3o2)cc1=O +Cc1cc(Nc2cc(C)c(C#N)c(NCCOc3ccccc3F)n2)n[nH]1 +Cc1ccccc1N1CCN(C(=O)c2ccc(F)cc2Cl)CC1=O +Nc1nc(N)c2c(Cl)c(NC(=O)Cc3ccc(Br)cc3)ccc2n1 +NC1(Cc2cccc(Cl)c2)CCN(c2ncnc3[nH]ccc23)CC1 +O=C(C[n+]1ccn2cccc2c1-c1ccccc1)c1ccccc1 +O=C(O)C=Cc1ccc2c(c1)c(CCc1ccccc1)cn2-c1ccccc1 +COc1ccc(Br)c(Cn2cc(CCCCC(=O)NO)nn2)c1 +CCC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 +COc1cc(-c2cn(CC(=O)Nc3cccc(F)c3F)nn2)ccc1-n1cnc(C)c1 +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OC[Si](C)(C)c2ccccc2C)c1 +CCCC(CCC)n1cc2c3c(nc(C)nc31)N(c1ccc(C#N)cc1C)CC2 +O=C(NCCCN1CCCC1)c1ccc(C=C2CCCn3c2nc2cc(Cl)ccc2c3=O)cc1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(I)cc1-c1cn[nH]c1 +CC1(C)CC1COc1cc(C(F)(F)F)ccc1C(=O)Nc1cc[nH]c(=O)c1 +Cc1n[nH]c2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)cc3)cc12 +NCCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1 +Cc1c(S(=O)(=O)Nc2ccc3nccc(N4CC(C)NCC4C)c3c2)sc2ccc(Cl)cc12 +O=C(O)c1cccc(S(=O)(=O)N2CCc3ccc(F)cc3C2)c1 +CC(C)n1c(-c2ccnc(N)n2)cc2c1CCNC2=O +CCn1c(-c2ccc(NS(=O)(=O)C3CC3)cc2)c(C#N)c2ccc(OC(F)F)cc21 +CCN1CCC(c2ccc(C(=O)Nc3cc(Oc4cc5ccn(C(=O)NC)c5cc4OCCCF)ccn3)cc2)CC1 +CNC(C)C(=O)NC1CCCC2CC3CCN(CCc4ccccc4F)CC3N2C1=O +Cc1oc(-c2cccc(-c3ccn[nH]3)c2)nc1C(=O)N(CC(=O)O)Cc1nc2ccccc2s1 +C#CCN1CCN(c2c(Cl)cccc2NC(=O)c2ccc(Br)o2)CC1 +COc1ccc2c(c1OCCNCC1COc3ccccc3O1)CCCC2 +O=C(Nc1ccc(CO)cc1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=C(NC1C2CC3CC(C2)CC1C3)C1CCCN1Cc1ccc(Cl)cc1 +CC1CN(c2ccc(Nc3ncc4c5cc[nH]c(=O)c5n(C5CCCC5)c4n3)nn2)CCN1 +CCOCn1nnc(-c2ccc(F)cc2)c1-c1ccnc(Oc2cccc(NC(C)=O)c2)n1 +Cc1nc(-c2cnn(C)c2-c2ccc(Cl)cc2C#N)c2c(N3CCC3)ncnn12 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(CO)CC4)cc2)CC3)cc1 +CCCC(CCC)C1=C(Br)c2nc3ccccn3c2C(=O)C1=O +Cc1cc(C)c(CN2CCc3ccc(OC4CCOC4)c(Cl)c3C2=O)c(=O)[nH]1 +COC(=O)CN(Cc1ccccc1OC)CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(c2ccccc2)CC1 +CCCOC(=O)NC1CCN(C(=O)OC2C3CC4CC(C3)CC2C4)C1 +N=C(Nc1ccc2ccn(CCN3CCCCC3)c2c1)c1cccs1 +Cc1ccc(C(C)(O)c2ccnc(Nc3ccc(C#N)cc3)n2)cc1 +O=C(NCCc1ccccc1)NC1C2CC3CC(C2)CC1C3 +Cc1c(C(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CN(C)CC4)c2)nnn1-c1nonc1N +CCOC(=O)c1nnc2n1CCN(C(=O)CC(N)Cc1cc(F)ccc1F)C2 +Nc1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2nc(CCCCc3ccc(F)cc3)sc2n1 +C=C1CCC2C(C)(C)CCCC2(C)C1CCC(C)=CCn1c[n+](C)c2nc[n-]c(=NOC)c21 +CCOC(=O)C1CCc2c(sc3ncnc(Nc4cc5sc(=O)[nH]c5cc4OC)c23)C1 +O=C(NCc1cccc(O)c1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 +CC(C)C(=O)Nc1ccc(F)c(C2(C)N=C(N)N(C)C(=O)C2(C)C)c1 +COc1ccc(CNc2nc(-c3ccccc3)c(Cc3ccccc3OC)s2)cc1 +COc1cc2ncnc(N3CCN(C(S)=Nc4ccc(Cl)c([N+](=O)[O-])c4)CC3)c2cc1OC +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)CCc1ccccc1)C2 +O=C(NC(Cc1ccccc1)C(=O)NC(C=C[N+](=O)[O-])CCc1ccccc1)OCc1ccccc1 +C[Si](C)(C)CCOCOc1cc(C(F)(F)F)ccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(S(=O)(=O)NCCCN4CCCC4)cc3)nnc2c1 +CNC(=O)N1C(=O)N(c2cncc(Cl)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1S(C)(=O)=O +CC12CCC3C4CCC(=O)C=C4CCC3C1CCC21CCCO1 +CC1(C)C2CC=C(C[N+](C)(C)Cc3ccc(-c4ccccc4Cl)cc3)C1C2 +O=C(OCCCCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)c1ccc(O)cc1O +COc1cc(C)c(-c2nc3ccc(C(=O)Nc4ccc(C)c(C)c4)cc3[nH]2)c(C)c1 +Cc1cc(C)cc(Nc2nccc(-n3cc(C)c(CN4CC(O)C4)c3)n2)c1 +COc1nc(-c2nc3n(n2)CCCC3c2cc(C(C)(C)C#N)ccc2Cl)ccc1-n1cnc(C)c1 +CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(F)nc3)cc2s1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2ccc(Cn3ccc(=O)[nH]3)cc2)c1 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccn1)CC2 +O=c1[nH]c2ccc(O)c(-c3ccc(S(=O)(=O)NCCBr)cc3)c2c2ccsc12 +O=c1[nH]c2c(C(F)(F)F)cccc2c(=O)n1CCCCCn1ccnc1 +COc1cc2c(NC3CCN(C(C)C)CC3)nc(N3CCCN(C(C)C)CC3)nc2cc1OCCCN1CCCC1 +CC1C(=O)NCC1C(=O)Nc1cc(-c2cccc(OC(F)(F)F)c2)n(-c2cccc(F)c2)n1 +CN1C2CCCC1CC(NC(=O)n1c(=O)[nH]c3ccccc31)C2 +CCOP(=O)(O)c1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 +CN1C2COCC1CC(NC(=O)c1cn(-c3cnccn3)c3ccccc13)C2 +CCc1c(-c2nsc(-c3ccc(CC(C)C)c(C#N)c3)n2)ccnc1CCCC(=O)O +CC(C)C#Cc1csc2c(NCC(N)Cc3ccccc3)nc(-c3ccncc3)nc12 +O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c2c1OC1(CCSCC1)O2 +CC(Cc1ccc(Cl)cc1)S(=O)(=O)Nc1ccccc1S(N)(=O)=O 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+CN(C(=O)c1ccc(Cn2cccn2)cc1)C1CCN(C2CCC2)C1 +COc1cc2c(=O)n(Cc3ccc4c(c3)OCO4)cnc2c(OC)c1OC +O=C(O)C1=Cc2cc(C(F)(F)F)ccc2OC1C(F)(F)F +CCCCCCC(Cc1ccc(OC)c(OCCc2ccccc2)c1)NCCC +O=c1[nH]nc2c3c([nH]c4cccc1c43)CN(C1CCCCC1)C2 +COCC(C)NC(=O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12 +Cn1c(CN2CCC(c3cccc(C(F)(F)F)c3)CC2)nc2ccccc21 +O=C(Nc1cnccc1Br)c1cccc(-c2ccc3ccccc3c2)c1 +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5ccccc5F)no4)cc3)cc2)C(=O)NC(=O)NC1=O +CC12CCC3C(C(SCc4ccccc4)CC4=CC(=O)CCC43C)C1CCC2=O +O=C(NS(=O)(=O)c1cccc(Br)c1)c1ccc(Cl)cc1Cl +CC1CCCN1c1cccc(Nc2cc(-c3cccc(C(N)=O)c3)nn3ccnc23)n1 +CN(C)CCCN1CCN(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 +O=C(Nc1nc2ccc(C(F)(F)F)cc2s1)N1CCC(F)(c2ncc(CC(O)CO)cc2Cl)CC1 +COc1cccc(NC(=O)Nc2nc3nn(C)cc3c3nc(-c4ccco4)nn23)c1 +N#Cc1cccc(-c2cc(COCC3(c4ccccc4)CCNCC3)cc(C(F)(F)F)c2)c1 +O=C(O)c1ccc(Oc2ccc3c(c2)B(O)OC3)cc1 +CC(NC(=O)Nc1cc2[nH]nc(N)c2cn1)c1ccc(F)c(F)c1 +CCCCN(C)CCNC(=O)c1ccc(Cn2c(=S)[nH]c3ccc(Br)cc3c2=O)cc1 +Oc1ccccc1-c1nc(NC2CCNC2)c2ccccc2n1 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+CCCCOC(=O)c1ccc(NC(=O)Nc2cc(C(C)(C)C)nn2C)cc1 +CC1CCCCN1C(=O)C(CCn1cccc1C#N)NS(=O)(=O)c1cc(Cl)c(N)c(Cl)c1 +CC(C)(C)Cc1nc2cc(S(=O)(=O)C3CNC3)ccc2n1CC1CC1 +O=C(O)Cc1sc(Nc2ccccc2Cl)nc1-c1ccc(Oc2ccccc2)cc1 +COc1cc(C2=C(c3c[nH]c4ccc(I)cc34)C(=O)NC2=O)cc(OC)c1OC +C=CCN1CCC(C(=O)NO)C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 +CC1(C)NC(=O)N(CC(COc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)N(O)C=O)C1=O +CCN(Cc1ccc(-c2cc(OCc3ncccc3C(N)=O)c3cccnc3c2)cc1)C(C)=O +CC(Oc1ccc2[nH]nc(-c3nc4cc(CCO)ccc4[nH]3)c2c1)c1c(Cl)cncc1Cl +CCS(=O)(=O)c1ccc(-c2cc(Cl)ccc2OCC(=O)O)c(C)c1 +CN1CC(CNC(=O)OCc2ccccc2)CC2c3ccc(C(C)(C)C)c4[nH]cc(c34)CC21 +CN1CCN(c2nccc(NCCNc3ccnc4cc(Cl)ccc34)n2)CC1 +COc1ccc2[nH]c(CN3CCc4ccccc43)c(CCNC(=O)C3CCC3)c2c1 +CC1CCN(C(=O)C(CCn2cccc2C#N)NS(=O)(=O)c2cccc3cc[nH]c23)CC1 +CCOc1cc(C)c(CC(N)C(=O)NC(C)C(=O)NCCCc2ccccc2)c(C)c1 +Cc1cc(CCC2COC(N)=N2)ccc1Nc1ncc(Cl)cn1 +COc1ccc(CN2C(C(Cc3c[nH]c4ccccc34)NC(=O)C(N)Cc3ccccc3)=NNC2CCc2ccccc2)cc1 +CN1CCN(Cc2cccc(C(=O)C=Cc3ccc(C=CC(=O)NO)nc3)c2)CC1 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+CNC(=O)C=Cc1cnc(N)c2c(-c3ccc4c(c3)OCO4)csc12 +O=C(Nc1nnc(S)s1)NC(Cc1ccccc1)C(=O)NCc1ccccc1 +O=c1[nH]c(C2CCC2c2ccccn2)nc2c1cnn2C1CCC(F)(F)CC1 +COc1ccc(CCCC(=O)NC(NC(=NC#N)Nc2ccccc2C)C(C)(C)C)cc1 +Cc1c(C(=O)NC(=O)C2CCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +COc1cc(-c2nc(Cc3ccc4[nH]ncc4c3)c3ccccc3n2)cc(OC)c1OC +CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1nc(-c2ccccc2)c2ccccc2n1 +COc1ccc(-c2c(-c3cc(OC)c(OC)c(OC)c3)coc2C=O)cc1 +COC(=O)c1c(C)[nH]c2c1C13CC1CN(C(=O)c1cc4cc(OC)c(OC)c(OC)c4[nH]1)C3=CC2=O +CC1CC(=O)NN=C1c1ccc2c(NCc3ccccc3)ncnc2c1 +C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(Br)ccc3n2Cc2cccc(C(=N)N)c2)cc1 +CC1CCCN1C1CCN(c2ccc(NC(=O)NC3CCCCC3)cc2)C1 +CC(C)Oc1ccccc1OCCNCc1cccc(C2CCCC2)c1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1=O)NCc1ccccc1-c1c[nH]cn1 +CCC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3cccc(Cl)c3)n[nH]c2C1(C)C +COc1ccccc1-c1ccc(CC(NC(=O)C2(C(=O)N3CCCC3)CCCO2)C(=O)O)cc1 +OC(CNC1CCC(C(c2ccccc2)c2ccccc2)OC1)c1ccccc1 +CN1C2CCC1CC(OC(=O)c1cn(CC(F)F)c3ccc(F)cc13)C2 +NC(COc1cncc(C=Cc2ccncc2)c1)Cc1ccc2ccccc2c1 +CC(C)(CC(=O)NC1CC1c1ccccc1)NCC(=O)N1CCCC1C#N +CCCC1=Nc2cc(C(=O)NCCCOCC)ccc2Sc2ccccc21 +COc1cc(OC)c(F)c(-c2ccc(C(=O)Nc3ncc(CN4CCCC4)[nH]3)c3nccnc23)c1F +Cc1ccccc1S(=O)(=O)Oc1ccc2ccc(O)cc2c1 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CC(C)(C)C1)C2c1ccc(Sc2nc3ccccc3[nH]2)o1 +CC(=O)NC1CCC(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +COc1c(C(C)=O)c(O)c(OCc2ccc(Br)cc2)c2occc12 +CC(=O)Oc1cc(OCCCCO[N+](=O)[O-])cc2oc(-c3ccccc3)cc(=O)c12 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c(C)c1 +COCc1ncc(-c2ccc3nn(C)c(C4CCOCC4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +CCCCC1CN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CCN1C(=O)Cc1cc[n+]([O-])cc1 +O=C(O)COc1cc2c(c(Cl)c1Cl)C(=O)C(CC1CCCC1)C2 +COc1cc(C2C(C#N)=C(N)Oc3cc(N)ccc32)cc(Br)c1OC +Cc1nc(-c2ccccn2)nc(NCCc2ccccc2)c1Cl +CN(C)S(=O)(=O)N(CCC(F)(F)F)c1sc2ccccc2c1Br +COCCOc1n[nH]c2cc(NC(=O)NC3CCCN(Cc4c(F)cccc4OC)C3)ncc12 +CCCN1CCC=C(c2c[nH]c3ccc(NC(C)=O)cc23)C1 +CCC(=O)NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21 +OCC1OC(c2cccc(-c3ccccc3)c2)C(O)C(O)C1O +CC1CC(c2ccc3[nH]c(-c4ccc(Br)s4)nc3c2)=NNC1=O +CCCCCCN(C(=O)c1ccc(CCCCC)cc1)C(CC)c1nc2ccccc2c(=O)n1-c1ccccc1OC +CCOC(=O)N1CCc2c(sc(N)c2C(=O)c2cc(OC)c(OC)c(OC)c2)C1 +COc1cc(C=C2CCC(=Cc3ccc(OCCn4ccnc4C)c(OC)c3)C2=O)ccc1OCCn1ccnc1C +CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(CCC(c2ccccc2)C2CCN(S(C)(=O)=O)CC2)CC1 +CC(C)C(NC(=O)c1nn(Cc2ccc(F)cc2)c2ccccc12)C(N)=O +CCCCC(CCCC)CN(NC(=O)c1ccc(CN2CCN(C)CC2)cc1)c1nc(C#N)ncc1Br +COCC1OC(n2cnc3c(Nc4ccc(O)c(F)c4)ncnc32)C(O)C1O +CCCN1C(=O)C(O)(CC(=O)c2cccnc2)c2cc(Br)ccc21 +O=c1[nH]c2cc(-c3ccc(Cl)cc3)[nH]c2c(=O)n1CCN1CCN(c2ccccc2Cl)CC1 +CCOC(=O)N1CCCOc2ccc(Nc3ncc(Cl)c(Nc4c(F)cccc4C(=O)NC)n3)cc21 +O=C(C=Cc1ccc(Cl)c(Cl)c1)NCCCCCN1CCC(c2c[nH]c3cc(O)ccc23)CC1 +CC1CC(O)(c2ncc(-c3cc(Nc4nccc(C(F)(F)F)n4)cc(-c4cn[nH]c4)c3)s2)CCC1C(=O)O +COc1ccc(C=C(C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O +OC1(C(F)(F)F)c2ccccc2-c2c(-c3cnco3)cccc21 +CCCCCS(=O)(=O)CCCCCCCCCCC(=C(CC)c1cccc(O)c1)c1ccc(O)cc1 +CC12CCC3c4ccc(O)cc4CCC3C1Cc1c(CO)n[nH]c12 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+CN(CC(O)Cn1c2ccccc2c2ccccc21)S(C)(=O)=O +NCc1ccc(CNC(=O)C2C(C(=O)Nc3ncc(Br)s3)C3C=CC2C32CC2)cc1 +CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c3nc(OC)n4C)c2Cl)cc1 +c1cnc2ccc(Cc3nnc4ncc(-c5cnn(C6CCNCC6)c5)nn34)cc2c1 +CCN(c1cc(-c2ccc(CN3CC(F)C3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1 +O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)c(OCCCN3CCOCC3)cc2n1CCO +CC(OC(=O)Nc1c(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)nnn1C)c1ccccc1 +O=C(NC1CN2CCC1CC2)c1cc2cc(F)ccc2s1 +COc1ccc(S(=O)(=O)N(C)c2nc3ccccc3c(=O)o2)cc1 +O=C(O)C1CN(Cc2ccc3c(c2)OCc2c-3noc2-c2onc(-c3ccccc3)c2C(F)(F)F)C1 +CC(C)CC(=O)NC1(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)COC1 +O=C(c1n[nH]c2c1CN(CC(F)(F)F)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 +C=C(c1ccc(N(C)C)c(C#N)c1)c1cc(OC)c(OC)c(OC)c1 +CC=C1C(=O)CC2C3CCC4=CC(=O)CCC4(C)C3CCC12C +CC(=O)Nc1nc2ccc(-c3ccc(N)nc3)cc2s1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(Cc3c(F)cccc3Cl)CC2)C1 +CC(C)CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1C(=O)N(C)N=Cc2ccccc21 +COc1nccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)c1Cl +COCC(NC(=O)Nc1cc2[nH]nc(NC(C)C(F)(F)F)c2cn1)c1ccccc1 +NC1=NC(c2cc(NCc3nn(C(F)F)cc3Cl)ccc2F)(C(F)F)C2CC2O1 +CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C(C)c2ccc(F)cc2)C1 +COc1ccc2c(c1)-c1nc(-c3ccccc3)[nH]c1CC2 +Cc1nnc2n1-c1ccc(C#CCN3C(=O)CSc4ccccc43)cc1C(c1ccccc1F)=NC2 +COc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)NCCCc3ccccc3)cc1)C2 +COc1cc(OC2CCN(C(C)=O)CC2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +O=c1c(NCCc2ccc(Oc3ccccc3)cc2)c(Nc2ccncc2)c1=O +CCc1cc(-c2ccccc2)cc(CC)[n+]1-c1ccc(S(N)(=O)=O)cc1 +CCCCCCC(C)(C)c1ccc(C2CCCC(O)C2)cc1 +CC1(C)C(=O)N(C(=O)NCC2CCN(CC3(O)CCOCC3)CC2)c2cc(F)ccc21 +Cn1ccc(-c2cc(S(=O)(=O)c3ccccc3)cc3c4c(oc23)CCNC4)n1 +CC(C)c1nc(-c2ccccc2)cc(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +COc1ccc2cc(C3C(O)C(=O)N3c3cc(OC)c(OC)c(OC)c3)ccc2c1 +N#Cc1c(-c2cccc(F)c2)c2c(=O)[nH]c(=O)[nH]c2[nH]c1=O +COc1ccc(-c2c[nH]c3ccc(-c4nnc(N)s4)cc23)nc1OC +Cc1cccc(Cl)c1-c1nc(CN2CCC(C(=O)NCCCN3CCC(C(C)C)CC3)CC2)c(C)o1 +COc1ccccc1C=C1Oc2ccc(F)cc2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +CN(C(=O)Cc1ccccc1)C1CC2(CCCO2)CCC1N1CCCC1 +CCN(c1cc(-c2ccc(CN3CCCNCC3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1cccs1 +COc1cc2c(cc1O)oc(=O)c1c2c(-c2ccc(O)cc2)c2c3cc(OC)c(O)cc3ccn21 +O=S(=O)(c1ccccc1)N(Cc1ccccc1OC(F)(F)F)c1cc2ccccc2s1 +CCCNCc1c(-c2ccccc2)c2cc([N+](=O)[O-])ccc2n1C +NC1=NC2(c3cc(-c4cccnc4F)ccc3Oc3c(F)cc([N+]4=CCOCC4)cc32)c2nccn21 +Cc1cccc(C)c1OCC(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)NC(=O)OC1COC2OCCC12 +Cn1c(N2CCCCC2)cc(OCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O +Cc1ccc2c(C3CCN(CCN4CCN(C(C)C)C4=O)CC3)cn(-c3cccc(C(F)(F)F)c3)c2c1 +Cc1cccc(NC(=O)c2cncc(N3CC4CNCC4C3)c2)c1 +CN(Cc1ccc(C(=O)O)cc1)CC1CCCCN1CC(=O)Nc1ccc(Oc2ccccc2)cc1 +CCCCCCOP(=O)(O)C1=CC(OC(CC)CC)C(NC(C)=O)C(N)C1 +Nc1cnc(-c2ccc(C3CCC3)c(OCc3cccnn3)c2F)cn1 +O=c1sc2ccccc2n1CCCCN1CCN(Cc2ccccc2)CC1 +COc1ccc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)cc2F)c(F)c1 +COc1ccc(-n2[nH]c3c(cnc4ccc(Cl)cc43)c2=O)cc1 +O=C(O)C1(COc2ccc(-c3ccc(-c4ncc(C(F)(F)F)[nH]4)cn3)cc2)CCOCC1 +O=c1[nH]sc2c1c(=O)c1cc(F)c(-c3cccnc3)cc1n2C1CC1 +O=C(O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2Oc2ccccc2)cc1 +Cn1c(N2CCNC(c3ccc(Cl)c(Cl)c3)C2)nc(-c2ccncc2)cc1=O +CC(=O)Nc1ccc(C=CC(=O)N(C)Cc2cc3ccccc3n2C)cn1 +CCc1c(C)[nH]c(=O)c(-n2cccc2)c1Cc1cc(C)cc(C)c1 +Cc1cncn1CCCn1c(=S)[nH]c2sc3c(c2c1=O)CCC3 +Cc1ccc(-c2ccccc2C=NNCCN2CCCC(C(=O)O)C2)cc1 +CCOC(=O)CC1OP(=O)(OCC2C=CC(n3cc(C)c(=O)[nH]c3=O)O2)Oc2cccc(Cl)c21 +CCCc1cc(-c2cncc(OCC(N)Cc3c[nH]c4ccccc34)c2)cc2c(C)n[nH]c12 +Oc1cc(-c2ccccc2)ccc1Cn1cncc1CNc1ccc(-c2nc3ccccc3s2)c(-c2ccccc2)c1 +CCOC1CC(C(=O)Nc2ccc(N3CCOCC3=O)cc2)N(C(=O)Nc2ccc(Cl)cc2)C1 +Cc1nn2c(N3CCN(C)CC3)cc(C(C)(C)C)nc2c1-c1ccccc1 +O=C(CC12CCC(C(=O)O)(CC1)CC2)N1CCc2c(n(Cc3ccc(Cl)cc3)c3ncccc23)C1 +COC(=O)Nc1ccc2c(c1)OCCCCCCC(NC(=O)C=Cc1cc(Cl)ccc1-n1cnnn1)c1nc-2c[nH]1 +O=C(NC(=O)c1c(F)cccc1Cl)NC1c2ccccc2-c2ccccc21 +O=C(Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)c(F)c1)c1ccccc1F +Cc1ccc(NN2C(=O)OC(C)(c3ccc(Oc4ccccc4)cc3)C2=O)cc1 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+O=C(c1cn(CC(F)(F)F)c2ccc(Nc3nccc(-n4cc(CN5CC(O)CO5)cn4)n3)cc12)C1CC1 +CCCCN(CCCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2ccc(Cl)cn12 +COc1cc(-c2ccc3ncc(C(C)=O)c(Nc4ccc(CCN(C)C)cc4)c3c2)cc(Cl)c1O +CCC(NCCc1cccs1)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)CCN)CC1 +CC(C)NC(=O)N1CC2CC=C(c3ccc(CCN4CCCC4)cc3)C2C1 +CNC(=O)Cn1c(=O)n(C2CCN(C3CCC(c4ccccc4)CC3)CC2)c2ccccc21 +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Br)o1)Nc1ccc([N+](=O)[O-])cc1-3 +NC(=O)c1ccc(NC2CCCCC2N)nc1Nc1cccc(-n2nccn2)c1 +CNCCCn1c(-c2ccccc2)cc(C(=O)Nc2cccc(C(F)(F)F)c2)c1C +O=c1[nH]nc2c3c([nH]c4cccc1c42)CCCC3 +CC1CN(c2cc(-c3n[nH]c4ccc(-c5ccc(C(=O)NCCO)cc5)cc34)ncn2)CC(C)O1 +COCCOc1ccccc1C1c2c(n[nH]c2C(C)(C)CO)C(=O)N1c1ccc(-c2ccon2)cc1 +O=C(O)c1c(NS(=O)(=O)c2ccccc2NCCc2ccccn2)ccc2c1CCCC2 +CCN(CC)CCCN(CC)CCCOc1ccnc2cc(Cl)ccc12 +O=C1CCc2ccc(CC3CC4CCC(C3)N4CC3COc4c(ccc5c4CC(=O)N5)O3)cc2N1 +O=C1C=CC2(CC(c3cccc(Cl)c3)OC(c3cccc(Cl)c3)O2)O1 +CN(C)CCCNC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +CS(=O)(=O)Nc1ccccc1C1CCN(C(=O)C(COCc2ccc(Cl)c(Cl)c2)NCc2ccccc2)CC1 +Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)nc5)cc(C(F)(F)F)nc34)cn2)cn1 +N#Cc1c(N)nc(SCc2cccc(C(N)=O)c2)c(C#N)c1-c1ccccc1 +CC1(C)CC(CCNc2cccc(C#N)c2)(c2ccccc2)CCO1 +COc1cc(OCc2csc(-c3ccc(C(=O)N4CCC4)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CNC(=O)N1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(-c3ccsc3)nc(-c3ccccc3)n2)CC1 +CC1CN(Cc2cc(Cl)ccc2CC(=O)O)CCN1S(=O)(=O)Cc1ccccc1 +Nc1ccccc1-c1cnnn1-c1ccc2c(c1)C=CS(=O)(=O)O2 +C=CCN1c2ccccc2NC(=O)C1(C#CC1CC1)C(F)(F)F +CC#Cc1ccc(C2CC3CCC(C2C(=O)OC)N3C)cc1 +O=S(=O)(c1ccc(N2CCOCC2)nc1)N(Cc1ccc(OC(F)(F)F)cc1)c1nc2ccc(Cl)cn2c1Cl +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2cccc(Cl)c2)CC1 +O=S(=O)(c1cccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)c1)N1CCCC1 +Nc1nc(OC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CCOC(=O)C(=O)C=C(O)c1cn(Cc2ccccc2)c2ccccc12 +CCCC(Cc1ccc(C(=O)NCCC(=O)O)cc1)C(=O)c1cc2cc(Cl)ccc2n1-c1ccc(Cl)cc1 +O=c1cc(Cn2c(C3CCC3)nc3c(Cl)ccnc32)c2ccc(F)c(F)c2[nH]1 +C=C(c1cc(N(CCC)CC2CC2)nc(C)n1)c1c(OC)cc(OC)cc1OC +CC1(C)CCC(C)(C)c2nc(-c3cc(-c4ccc(C(=O)O)cc4)cs3)cnc21 +NCC1(c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)cn(C)c2=O)C3=O)c(OC)n1 +Cc1cc(C)cc(C(=O)N2CCC(NCc3cnc4ccccc4c3)CC2Cc2ccccc2)c1 +COc1cc(S(=O)(=O)c2cc(Cl)cc(Cl)c2)cc2c3c(oc12)CCNC3 +Nc1ncnc2c1nc(Sc1cc3c(cc1I)OCO3)n2CCNCCCCCCC(=O)NO +CN(C)C1CCC(Nc2ncnc3[nH]cc(C4CC4)c23)CC1 +Cc1ccc(N(CCN2CCC(OCC(=O)O)CC2)C(=O)c2ccccc2)cc1 +CCOP(=O)(OCC)C(Cc1ccc(F)cc1)c1cc2ccccc2s1 +O=C(O)c1ccc(CN(Cc2ccccc2)C(=O)c2ccc(Oc3c(F)cccc3F)cc2)cc1 +CC1CCNc2cc3oc(=O)cc(C(F)(F)F)c3cc21 +CC(O)CN1CCC(c2ccc(Nc3ncc4ccc(-c5ccccc5N(C)S(C)(=O)=O)n4n3)cc2)CC1 +COc1ccc(-c2cnnn2-c2cc(Br)c(OC)c(Br)c2)cc1O +CCc1c(N)ncnc1N1CCC(c2nc(-c3cccc(Cl)c3)cn2CCN2CCCC2)CC1 +COc1ccc(C)n2nc(CCc3nc(-c4cncs4)cn3C)nc12 +CCCCNc1c(CCCC)nc2ccc(C=CC(=O)NO)cn12 +Cc1sc(C(C)Nc2nccc(N3C(=O)OCC3C(C)C)n2)nc1-c1ccc(Cl)cc1 +CSc1ccccc1-c1cc2[nH]c3ccc(O)cc3c2c2c1C(=O)NC2=O +CC(=O)N1CCC(C(=O)N2CCC(N(C)C(=O)c3ccc(N4CCOCC4)cc3)C(c3ccc(Cl)c(Cl)c3)C2)CC1 +CC(C)CC(NC(=O)c1cccc(-c2cccc(Cl)c2)n1)c1nccs1 +CCOC(=O)C1=C(N)N(c2cccnc2)C2=C(C(=O)CC(C)(C)C2)C1c1c(C)nn(-c2ccc(C)cc2)c1Cl +CC1CCN(CCCOCCCOc2ccc(C(C)(C)C)cc2)CC1 +CCCn1c(=O)c2[nH]c(-c3ccccc3)nc2n(CC[S+]([O-])CC)c1=O +Cc1cn(C2C=CC(COP3(=O)OCc4cc(CCC(=O)OCc5ccccc5)ccc4O3)O2)c(=O)[nH]c1=O +O=C(O)c1cc(NCCO)c2nc(N3CCOCC3)nc(-c3ccccc3O)c2n1 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2cccc(C)n2)c1 +COc1cccc(Oc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCCOc2ncc(C)cn2)c1 +CCCc1c2ccc(C)n2cc[n+]1CC(=O)c1ccc(OC)cc1 +COCc1cc(-c2nn(C)c3cnc4cc(OC)c(OC)cc4c23)ccc1C#N +Cc1cc(Nc2n[nH]c3ncc(F)cc23)nc(-c2ccccc2)c1C +CCCSc1[nH]c2cccc3c2c1CC1C3C=C(C)CN1C +CC1(O)CC(NC(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)cn4)ccc3n2)C1 +COc1cccc(CN(C(=O)OC2CC3CCC(C2)[N+]3(C)C)c2ccccc2)c1 +CC(C)(C)OC(=O)N1CCC(Oc2cccc3c2CCN3c2ccc(S(C)(=O)=O)cc2)CC1 +CCC(C)C(NC(=O)C(C)NC)C(=O)N1CCCC1C(=O)NC(c1ccccc1)c1ccccc1 +COc1ccc(-c2nc(NCc3ccc(O)cc3)sc2Cc2ccccc2)cc1 +CCN(CC)CCNC(=O)c1cccc2c(Nc3cc(I)c(NS(C)(=O)=O)cc3OC)c3ccccc3nc12 +CC(C)N(C(=O)C1CCC2C3CCC4NC(=O)C=CC4(C)C3CCC12C)C(C)C +CC(C)CN1CCCCC1C(=O)Nc1cc(C(C)(C)C)on1 +Cc1ccc(-c2ncccn2)c(C(=O)N2CCOC2Cn2ccc(-c3ccc(F)cc3)n2)c1 +O=C(O)C=NOC(c1ccc(OCc2nc3ccccc3s2)cc1Cl)C1CCCCC1 +CC(C)(CO)NC(=O)c1c[nH]c2ncc(Nc3cccnc3)nc12 +NS(=O)(=O)c1ccc(Oc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc1 +CCc1nc2ccn(Cc3ccccc3C(F)(F)F)c(=O)c2n1C1CCc2cc(-c3ccccc3-c3nnn[nH]3)ccc21 +O=C(Cc1ccc(Cl)cc1)Oc1ccc2c(c1)OS(=O)(=O)CC2 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc3c(cc1c2Cn1ccnc1)OCCO3 +O=C(Nc1ccccc1-c1nc2ccccc2nc1O)c1cccs1 +CCCCC(C=O)NC(=O)OC(Cc1ccccc1)CC(C)C +Nc1ncc(-c2ccc(C3(c4noc(-c5cocn5)n4)CCC3)cn2)cn1 +CN(C)C1CCN(C(=O)c2ccc3c(c2)ncn3-c2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)C1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCC(O)C2)c(-c2ccccc2)c1 +CN(Cc1cc(-c2ccc(F)cc2)ccc1O)CC(O)c1ccccc1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccsc2)c1C +[N-]=[N+]=Nc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 +C=CCNCC(O)COc1cccc2c(=O)c3ccccc3oc12 +C#CC(C)(C)Nc1c(C#N)cnc2cnc(NCc3cccnc3)cc12 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1nccc2ccccc12)C(C)C +CCN1CCCC1CNc1[nH]cnc2c3cc(Cl)ccc3nc1-2 +COc1ccnc2[nH]cc(C(=O)c3c(F)ccc(NS(=O)(=O)c4cc(F)ccc4F)c3F)c12 +O=C1CC(c2c(Cl)ccc(NC3CCOCC3)c2Cl)CC(O)=C1Sc1ccccc1Cl +O=C(CN(CCC1CCCC1)C(=O)N1CCCC1C(=O)Nc1ccc2c(c1)OCO2)NO +COCCCN1CCC(O)(CNC(=O)c2nc(C(C)C)n3ccccc23)CC1 +CCCc1ncc(Cc2cnc3ccccc3c2)c2cc(OC)c(OC)cc12 +CC(C)(C)c1nc2cc(S(=O)(=O)CC3CC3)ccc2n1CC1CCN(C=O)CC1 +O=C1OC(c2ccccc2Cl)CN1c1ccc2c(c1)CNCC2 +CN(C)c1ccc(-c2oc3c(ccc4ccccc43)c(=O)c2O)cc1 +N#Cc1cnn(CC(O)COc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)c1N +CC1CCCCN1c1nn(CC(C)(C)O)cc1NC(=O)c1cnn2cccnc12 +CC1c2c([nH]c3ccccc23)C2Oc3c(O)ccc4c3C23CCN(CC2CC2)C(C4)C13 +CCCC(Oc1cnn(-c2ccc(C)cc2)c1)c1ccc(C(=O)NCCC(=O)O)cc1 +Sc1nc(-c2ccc(Cl)cc2Cl)nn1Cc1cccc(Oc2ccccc2)c1 +Cc1oc(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)Nc2ccccn2)nc1C(=O)O +CCc1ccnc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 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+O=S1(=O)NC2(CN1CC(F)(F)F)C1CCC2Cc2cc(-c3cn(-c4cccc(F)c4)cn3)ccc2C1 +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)Nc5cc(F)c(F)c(F)c5)cn4c3)cc2)CC1 +CCNC(=O)C1OC(n2cnc3c(NNC(=O)c4ccc(C)o4)ncnc32)C(O)C1O +CC(C)CN(CCCN1CCN(CCCNCc2ccc(Cl)cc2)CC1)CC(C)C +NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(C(F)(F)F)cc2)cc1 +CCOc1cccc(Cl)c1C1CC(O)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +Fc1cccc(CNc2cccc(-c3cc(NCCN4CCOCC4)ncc3Cl)n2)c1 +CC(C)(C)c1cc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)ccc1N1CCCC1 +CC1(C(=O)Nc2nncs2)CC2c3ccccc3C1c1ccccc12 +CN1CCC(OC(=O)C(O)(c2ccccc2)c2ccccc2)CC1 +O=C(c1ccc(OCCCN2CC3CC2CN3C(=O)c2ccc(F)cc2)cc1)C1CC1 +CCC(C)(C)C(=O)C(=O)N1CCCC1C(=O)NCCCc1ccccc1 +NS(=O)(=O)NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F +O=C(NCc1ccccc1)c1ccc2c(c1)nc(NC1CCC(O)CC1)c1nccn12 +CC(C)COC(=O)OCC1OC(c2ccc(C3CC3)c(Cc3ccc4c(c3)OCCO4)c2)C(O)C(O)C1O +COc1cc2nccc(Oc3ccc4c(Nc5ccccc5)nn(C)c4c3)c2cc1OC +CN1CCN(c2ccc3nc(-c4ccc(=O)n(C)c4)n(Cc4ccccc4)c3c2)CC1 +NC1=NC2(CCO1)c1cc(NC(=O)c3ccc(Cl)cn3)ccc1Oc1ncc(C3=CCCOC3)cc12 +CC(C)c1cccc2c1C(=O)N(COC(=O)c1c(Cl)cccc1Cl)S2(=O)=O +CN1C2CCC1CN(S(=O)(=O)c1ccc(C(C)(C)C)cc1)C2 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cc(F)cc(-n2nccn2)c1 +O=C(CN1CC(CO)C(NC(=O)c2ccc(Cl)s2)C1)Nc1ccc(-n2ccccc2=O)cc1F +CC(C)N1CCC(CNc2ccc3nnn(-c4cccc(OC(F)(F)F)c4)c3n2)CC1 +COC(=O)c1ccc2c(c1)nc(SCCn1ccnc1)n2C +CC(C)OCCN(CCO)c1nc(N2CCCCC2)c2nc(N(CCO)CCOC(C)C)nc(N3CCCCC3)c2n1 +CCCCC12CC1(C(=O)CCC)C(=O)Nc1ccc(Cl)cc12 +OCCN1CCN(c2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1 +COc1cccc(CN2Cc3cc(OC)c(OS(N)(=O)=O)cc3CC2C)c1 +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCS(=O)(=O)CC5)ncn4)c3c2)cn1 +O=C(O)Cc1ccc(Oc2ccc(C(=O)NC3CCC3)cc2NS(=O)(=O)c2ccc(Cl)cc2)c(Cl)c1 +CC1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccccc4)cc32)C(Cn2cc(F)cn2)CN1 +CC(C)(NC(=O)c1cccc(-c2cccc(Cl)c2)n1)c1ncon1 +CCCCCc1ccc(S(=O)(=O)NCCc2c[nH]c3c(C)cccc23)cc1 +O=S1(=O)C=C(c2cccc(I)c2)S(=O)(=O)CCC1 +COC(=O)CC1(C(=O)Nc2cccc(C(=N)N)c2)CC(c2ccc(C(=N)N)cc2)=NO1 +CC(Nc1nc(NCC(O)CO)c(Cl)c(Nc2cc(C3CC3)[nH]n2)n1)c1ccc(F)cc1 +CN(C)c1ccc(N2Cc3cccc(C(N)=O)c3C2=O)cc1 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+O=C(O)C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc2ccccc2c1 +Cc1cc2c(-c3nc4c(c(C5(S(C)(=O)=O)CCC5)n3)OCC3COCCN43)cccc2[nH]1 +CCN(C(=O)COc1ccc2ccccc2c1)c1ccc(OC)nc1 +Cn1c2nc3ccccc3c-2c(NCCCN2C(=O)CCSC2c2ccc(F)cc2)c2ccccc21 +O=C1Cn2c(Cl)cnc(c2=O)NC(Cc2ccccc2)CNCCCCNCc2ccccc2CN1 +COc1cc2c(cc1OC)CN(CCCCn1cc(-c3ccoc3)c3ccccc31)CC2 +O=C(O)CCC(NC(=O)c1cccc(-c2ccccc2)n1)C(=O)N1CCN(C(=O)OCC(F)(F)F)CC1 +Nc1ncnc2c1c(-c1cc3c(Cl)cccc3[nH]1)nn2CC1CCNCC1 +CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C=O)cc2C)c1C +C=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCNC(C)=O +Cn1cc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cccc(Cl)c2)C(N2CCC2)CC3)cn1 +COc1ccc2c(c1)NC(=O)Cc1cnc(Nc3ccc(O)c(Cl)c3)nc1-2 +COc1cc(-c2cc(-c3cc(C)cc(Cl)c3O)nc3ncnc(N)c23)ccc1O +COc1ccc2c(c1)N(CC1CC1)C(C#CC1CC1)(C(F)(F)F)C(=O)N2 +CNC(=O)c1cc(S(=O)(=O)N2CCN(c3ccccn3)CC2)cs1 +Cc1cnc(NC(=O)c2cc(Oc3cnc(C(=O)N4CCCCC4)cn3)c3cc(C)oc3c2)cn1 +CCN(Cc1ccc2ncnc(S)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +CCOc1ccc(F)c(-c2nc(C)c3nnc4ccc(OC)nc4n23)c1 +CC1(C)CCCN(Cc2ccc(-c3cnc4[nH]c5cnc(C#N)cc5c4c3)cc2)C1 +CCCC1Cc2cc3c(C(F)(F)F)cc(O)nc3cc2NC1CC +CC(C)CC(C(=O)O)c1cc(Cc2cc(F)cc(F)c2)cc(-c2ccc(C(F)(F)F)cc2)c1 +CCc1c(CC)c(OC)c2c(C)cccc2c1OC(C)=O +NS(=O)(=O)Oc1ccc2sc(-c3ccccc3)cc(=O)c2c1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1C(=O)N1CCOCC1 +Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)OCc4ccccc4)c3Cl)cccc2s1 +COC1COCCC1NC1CCC(C(=O)N2CC3CC2CN3C(=O)CC(C)(C)C)(C(C)C)C1 +O=C(c1ccc(F)cc1)c1cc(F)ccc1C=COCCN1CCCC(C(=O)O)C1 +COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OC1COC2C(O)COC12 +O=c1cc(N2CCOCC2)oc2c(-c3ccc(Cl)cc3)csc12 +CC(O)(CSc1ccccc1Cl)c1cc2cc(Cl)c(C(F)(F)F)cc2[nH]1 +CCCCc1cc(=O)n2nc(-c3ccccc3)nc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(Nc1ccc[n+]([O-])c1)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +COc1cc(O)c(Cc2ccc(O)cc2)c2ccc3cc(O)ccc3c12 +COc1cc2c(Nc3ccc(Cl)cc3Cl)c(C#N)cnc2cc1OCCCN1CCOCC1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(N(C)CC)n3)C2)cc1 +NS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2ccccc2)cc1 +CC(C)(O)c1cn(-c2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)c(C(C)(C)c2ccccc2Cl)n1 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+COc1cc2nc(NC(=O)CN3CCN(Cc4ccc(C(F)(F)F)cc4)CC3)sc2cc1OC +Nc1ncnc2c1c(-c1ccc3ccccc3c1)cn2C1OC(CO)C(O)C1O +Cc1nc(-c2ncn3c2CN(C)C(=O)c2ccccc2-3)no1 +Cc1ccc2oc(=O)c(-c3cccc(OCCCN(C)C)c3)cc2c1 +COc1ccc(-c2cnnn2Cc2cc(OC)c(OC)c(OC)c2)cc1O +CNc1ccccc1C(=N)CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +COc1ccc2c(c1)c(CC(=O)Nc1cccc(SC)c1)c(C)n2C(=O)c1ccc(Cl)cc1 +CC1CN=C(c2ccc(NC(=O)c3ccc(C(=O)Nc4ccc(C5=NCC(C)N5)cc4)c(N)c3)cc2)N1 +O=C(O)C1=C(C(=O)Nc2ccc(OCc3c(F)cccc3Cl)c(Cl)c2)CCC1 +COc1cccc2c1OC1CCCC3CN(CCc4ccccc4)CCC231 +Cc1c(NC(CC(C)C)c2ccc(C(=O)NCCC(=O)O)cc2)cnc2ccccc12 +O=C(O)c1ccc(CCCN2C(=O)CCC2CCC(O)Cc2cccc(Cl)c2)cc1 +CCc1cccc(CC)c1-c1cc(SC)c2c(n1)CCCC2N(CC)c1cccc2ccccc12 +O=C(CCCO[N+](=O)[O-])Oc1cccc(C(=O)Oc2ccc(-c3cc(=S)ss3)cc2)c1Cl +O=C(O)CCc1ccc(OCc2ccccc2-c2ccc(F)cc2)cc1 +Cc1ccc2c(OCCN3CCN(Cc4cccc5cccnc45)CC3)cccc2n1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cccc(C(C)(C)C)c3)ccc2[nH]1 +OCC1OC(n2cnc3c(NN4CCCC(Sc5ccccc5)C4)nc(Cl)nc32)C(O)C1O +O=C(Nc1ccccc1)c1c(NO)cc(-c2ccc(Cl)cc2)oc1=O +CCCCCCCC(=O)N1CCN(C(C#N)c2cccnc2)CC1 +O=C1c2ccccc2CCCN1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1 +CCc1c(C(C)c2c(F)cccc2F)nc(SC2CCCC2)[nH]c1=O +Nc1ncc(-c2ccc(-c3cccnc3S(=O)(=O)C3CCS(=O)(=O)CC3)cc2F)cn1 +Cc1c(CCN2CCc3c(cnn3-c3ccc4c(c3)COC4=O)C2)ccc2c1COC2=O +OC(CNc1cccc2ccccc12)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21 +C=CC(=O)Nc1cc(Br)cc(-n2c(=O)cc(C)c3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +COC1COCCC1NC1CCC(C(C)C)(N2CCN(C(=O)OC(C)(C)C)CC2)C1 +COc1cc(N2CCCCC2)ccc1Nc1ncc2ccnc(NCC(C)(C)C)c2n1 +Cc1nc(C(=O)COc2ccc(OCCCCCc3ccccc3)cc2)sc1CCCC(=O)O +CCC(CO)Nc1cc(-n2ncc3cc(Cl)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +O=C(c1ccc(-n2cccc2)cc1Cl)N1CCCCc2ccccc21 +CC(=O)Nc1ccccc1COc1ccc(-c2ccc(-c3nc4c(C(=O)O)cc(C)cc4[nH]3)cc2)cc1 +COc1ccc(CCCc2nc(N)c3nn(-c4ccccc4)cc3n2)cc1 +CS(=O)(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1C#N +CNC(=O)c1cccc(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1C +CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)n1 +Brc1ccc(-n2c(-c3c(-c4ccccc4)[nH]c4ccc(Br)cc34)nc(-c3ccccc3)c2-c2ccccc2)cc1 +CCC1(CC)OC(S)=Nc2ccc(-c3ccc(C#N)n3C)cc21 +COc1ccc(Cn2ncc3[nH]c(-c4cc(NC(=O)Nc5ccc(Cl)c(Cl)c5)ccc4C)nc32)cc1 +O=C(Nc1ccc(C(=O)N2CC3COCCN3Cc3ccccc32)cc1)c1ccccc1-c1ccccc1 +O=S(=O)(NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1)c1ccccc1 +COc1cc(C(=O)c2c[nH]c(-c3ccc(N(C)C)cc3)n2)cc(OC)c1OC +CC1CCCN(S(=O)(=O)c2ccc(NC(=O)NCc3cccnc3)cc2)C1 +COc1ccc(Oc2ccc(NC(=Nc3ccccc3)NCCNc3ccnc4cc(Cl)ccc34)cc2)cc1 +CC(=O)OCC(COC(C)=O)c1ccc(NC(=O)c2ncc(C#N)[nH]2)c(C2=CCCCC2)c1 +CC(O)C(c1ccccc1)N1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +COCCCS(=O)(=O)c1cccc(Oc2cccc(-c3c(C)cnc4c(C(F)(F)F)cccc34)c2)c1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(N2CCNCC2)cc1 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1c(C)cccc1F)C(C)C +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2CF)o1 +COc1ccc(CC(C(=O)c2ccc(OC)cc2)=C(C(=O)O)c2ccc3nsnc3c2)cc1 +COc1ccccc1N1CCN(CCn2c(=O)[nH]c3cc(-c4cccc(Cl)c4)[nH]c3c2=O)CC1 +Cc1ccc(NC(=O)Nc2ccc(C=CC(=O)c3ccc(Cl)cc3)cc2)cc1 +COCc1nc2c(C(=O)Nc3nc4ccc(Cl)cc4o3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CC1c2ncn(-c3ccc(F)cn3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl +CCCCN(CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(c2ccccc2)CC1)C(C)=O +NC1=NC2(CCSCC2)N(OCCCOc2cccc(Cl)c2)C(N)=N1 +COc1ccc(CC(NC(=O)C(CC(=O)O)NC(=O)CCCOc2ccc(C(=N)N)cc2)C(=O)O)cc1 +Cc1cccc2c1[nH]c(=O)n2CC(=O)Nc1ccc2c(c1)CC1(C2)C(=O)NC(=O)N1C +CN1CCN(Cc2ccc3n2Cc2ccccc2N(C(=O)c2ccc(NC(=O)c4ccccc4-c4ccccc4)cc2Cl)C3)CC1 +COc1ccc2c(c1)-c1ccc3c(c1CO2)C(C)=CC(C)(C)N3 +CN(C)CCCOc1ccc(NC(=O)c2cc([N+](=O)[O-])c(Sc3c(Cl)cncc3Cl)s2)cc1 +NC(CNc1cc(-c2ccncc2)c(-c2cccc3ccccc23)nn1)Cc1ccccc1 +CCCn1c(=O)c2nc(C3CCC(OC(=O)c4cccc(S(=O)(=O)F)c4)C3)[nH]c2n(CCC)c1=O +CCCCCCCCC(C)(C)c1ccc(C2CC(O)CCC2CCCO)cc1 +CS(=O)(=O)c1ccc2c(c1)N(CCCN1CCC(C(=O)O)CC1)c1ccccc1S2 +OCC1OC(n2cnc3c(NC4CC4)ccnc32)C(O)C1O +COC(=O)c1ccc(CS(=O)(=O)NCB(O)O)cc1 +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccc(NC(=O)Nc3ccccc3)cc2o1 +COc1ccc(-c2ccc3ncc4c(c3n2)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C4)cn1 +CN1CCC(c2cc3c(-c4cncc(NCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +O=C(NCc1ccccc1)Nc1cccc(CCNCC(O)c2ccc(O)c3[nH]c(=O)ccc23)c1 +COc1ccccc1C(=O)C=Cc1ccccc1[N+](=O)[O-] +CC(C)c1cc(C(=O)N2Cc3ccc(Cl)cc3C2)c(O)cc1O +Fc1ccc(-c2ccc(OCC3CCN(CC4CC4)CC3)cc2)cc1 +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)N(CC)CC)c3ccc(F)cc3F)CC2)c(F)c1 +CCOCCn1nc(C)c2nc(NC3CCNCC3)nc(Nc3cc(C)ccn3)c21 +CC(C)CC(C(=O)O)c1cc(-c2ccc(C(F)(F)F)cc2)cc(-c2ccc(C(F)(F)F)cc2)c1 +O=C(Nc1ccc(-c2cccnc2)cc1)Nc1ccc(OC(F)(F)F)cc1Br +NC(=O)N1CCCc2cc(-c3cncc(C4CCC(=O)N4)c3)cnc21 +CCOCc1ccc2c(c1)nc(NC(=O)c1cccc(C(F)(F)F)c1)n2C1CCC(O)CC1 +CCCN(CCCNc1ccnc2cc(Cl)ccc12)Cc1ccsc1 +CCC(C1CC1)n1cc(C#N)nc(Nc2cc(C)c(OC)nc2C)c1=O +CC(C(=O)NO)N1CCC(C)(c2ccc(-c3ccccc3)cc2)C1=O +COc1cccc(-n2c(=O)n(CCC(N)c3ccccc3C)c(=O)n(Cc3c(F)cccc3F)c2=O)c1 +O=C1CC(NC(=O)C2COCC3CC=CCC(NC(=O)c4ccc(Cl)cc4)C(=O)N32)C(O)O1 +CCOC(=O)N1CC2CCC(C1)C2NCCNC(=O)c1ccccc1 +Oc1ccc2c3c1OC1C(OCc4ccccc4N=C=S)CCC4(O)C(C2)N(CC2CC2)CCC314 +O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OCc4ncccn4)cc3)cc12 +NS(=O)(=O)c1ccc(N2C(=O)c3c(Br)c(Br)c(Br)c(Br)c3C2=O)c(F)c1 +[C-]#[N+]c1ccc(Oc2ccc(-c3nc(NC(C)C(N)=O)cc(C(N)=O)n3)cc2)cc1 +OCC#Cc1cn2c(-c3ccc(-c4cnc(C5CC5)[nH]4)cc3)cnc2c(NCCC(F)(F)F)n1 +CC(C)c1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccccc2)nc2ccccn12 +C=CC(=O)Nc1ccccc1Nc1nc(Nc2ccnn2C)ncc1C +COc1cc2cncc(Cc3ccc4nc(C)ccc4c3)c2cc1OC +COc1ccc(C2CCCc3nc(SCc4c(F)cccc4Cl)n(-c4ccc(F)cc4)c32)cc1OC +Fc1ccccc1OC(CCN1CCN(c2noc3ccccc23)CC1)c1ccccc1 +COc1cccc(CNc2ccc(S(=O)(=O)Nc3cccc(C(C)(C)C)c3)cc2)c1O +CCc1c2c(nc3ccc4c(c13)N(C)CCO4)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC +Cc1cc(Cl)ccc1C1c2c(nn(-c3ccc(C(N)=O)cc3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F +CCCCCCCCCCCCCCCNC(=O)OCC1OCC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1 +COc1cc2c(cc1N1CCN(C)CC1)N(S(=O)(=O)c1ccc3ccccc3c1)CCC2=O +O=S(=O)(c1ccccc1)C1CCN(CCc2ccccc2)CC1 +CN(C)Cc1cccc(C23CCC(N(CCCN4CCN(C)CC4)c4nc5cc(F)c(F)cc5[nH]4)CC2C3)c1 +CC(C)(C)OC(=O)N1CCCC1CNc1cc(Nc2cccc(Cl)c2)nc2c(C=C3NC(=O)NC3=O)cnn12 +CC(=O)N1CCc2nc(N3CCN(Cc4ccc(F)cc4F)CC3)c(NC3CC(F)C3)nc2C1 +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCCCc1ccc(O)c(O)c1 +O=C(O)CCC=C1CC2CC(O)C(C=NNC(=O)Nc3ccc(Cl)c(Cl)c3)C2C1 +CN1C(=O)c2c(nn(Cc3ccc(-c4ccccc4)cc3)c2Nc2ccccc2)N2CC(C3CCOC3)N=C12 +COc1cc(OC)cc(N2C3CCC2CC(c2cnc(N)nc2N)C3)c1 +CC1CCC2C(C)C(OCCNCCNc3ccnc4cc(Cl)ccc34)OC3OC4(C)CCC1C32OO4 +COc1cc(-c2cccc(OC(F)F)c2)c(F)cc1-n1c2c(ccc1=O)CN(S(=O)(=O)Nc1ccon1)CC2 +O=C(CCO)NC1CCC(CCN2CCC(c3noc4cc(F)c(F)cc34)CC2)CC1 +CCC(=O)N1CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C(NC(=O)c2nc3c(s2)CN(C)CC3)C1 +[C-]#[N+]c1cccc(S(=O)(=O)c2ccc3c(c2)c2c(n3C)CC3CCC2N3)c1 +O=S(=O)(NCCCCCN1CCN(c2ccc(Cl)cc2)CC1)c1cnc2ccccc2c1 +Cc1ccc(-c2cn(CCCCCn3cccc(O)c3=S)nn2)cc1 +c1ccc2c3c([nH]c2c1)C(C1CCCCC1)NC(c1nc(-c2ccncc2)c[nH]1)C3 +COc1cc(C=C2SC(=Nc3ccccc3)NC2=O)ccc1O +CCOc1ccc(-c2c(NC(=O)c3ccc(OC(C)C)cc3)c(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1 +O=C(NCC1CN(c2ccc(N3CCCCC3=O)c(F)c2)C(=O)O1)c1ccc(Cl)s1 +O=C(Nc1ccc(C(F)(F)F)nc1)Nc1ccc(C2CNCCO2)cc1F +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccc(Cl)s2)[nH]c1=O +CN(C)CCc1c[nH]c2ccc(-n3cnc4cccnc43)cc12 +O=C(Cc1cccs1)Nc1cccc(-c2nc3ccccc3[nH]2)c1 +O=C(O)c1ccc2c(c1)nc(-c1ccc(OCc3cccc(-c4ccccc4)c3)cc1)n2C1CCCCC1 +Cc1nn(Cc2ccc(-c3nc4cc(F)ccc4[nH]3)cc2)c(C)c1CC(=O)O +Cc1ccc(-c2nc(NN=Cc3ccccc3[N+](=O)[O-])c3ccccc3n2)cc1 +O=C(NC1CCc2cc(F)ccc2C1Cc1cccnc1)C1CCC(CNS(=O)(=O)c2ccccc2F)CC1 +CCCC[S+]([O-])c1sc2nc(-c3nccs3)cc(-c3ccc(CO)cc3)c2c1N +N#Cc1ncc2nc1OCCCCCOc1cc(CC(O)CO)c(Cl)cc1NC(=O)N2 +Cc1ccccc1C#CC1CC(CN2CCCCC2)C(=O)N1C +CS(=O)(=O)CCNCc1nc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cs1 +CCCCCn1c(C)c(C(=O)c2ccc(OC)c3ccccc23)c2ccccc21 +COc1ncc(-c2ccc3nccc(-c4ccc(CN(C)CCO)cc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +Cc1c(C)n(Cc2cccc(OC(C)(C)C(=O)O)c2)c2ccc(C(=O)NC(C)c3ccc(C(C)(C)C)cc3)cc12 +COc1cc2ncnc(Oc3cnn(CC(=O)Nc4ccc(N(C)C)cn4)c3)c2cc1OC +NC(Cc1ccc(O)cc1)C(=O)NCCCCCCCCNC(=O)C(N)Cc1ccc(O)cc1 +CC1CN(c2nc(-c3ccncc3)nc3sc4c(c23)CCCC4)CCN1 +C(=CC1CCCN(CCCc2ccccc2)C1)c1ccccc1 +CN1CCN(c2cnc3c(NCCc4ccncc4)nc(-c4ccccc4)nc3n2)CC1 +O=C1CSC(c2c(F)cccc2F)N1c1cccc(Br)n1 +CC(C)n1c(Cn2nc(-c3cccc(O)c3)c3c(N)ncnc32)cc2ccccc2c1=O +CCN(C)c1nccc(N2CCC(Oc3ccc(C(C)NC(=O)c4sc(NC(C)=O)nc4C)cc3)C2)n1 +Cn1ccc(NC(=O)c2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)n1 +O=C(Nc1cc2[nH]nc(OCCO)c2cn1)NC(COC(F)F)c1ccccc1 +CC(C)(CCCOc1ccc(-c2ccc(Cl)cc2)cc1)CN1CCN(c2ccncc2)C1=O +CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1cc[nH]n1 +COc1cc2[nH]c(=S)n(Cc3ccncc3)c(=O)c2cc1-c1cnco1 +Oc1ccc(-c2nnc(-c3cc(O)c(O)cc3Br)s2)cc1O +Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCCCCCNc1c3c(nc4cc(Cl)ccc14)CCCC3)O2 +CC(=O)OCC1OC(n2c(Cl)nc3c(Cl)c(Cl)c(Cl)cc32)C(OC(C)=O)C1OC(C)=O +O=C(Nc1ccc(C(F)(F)F)c(Cl)c1)c1ccnn1CCc1ccncc1 +CC(C)OC(=O)C(C)NP(=O)(OCC1OC(n2ccc(=O)[nH]c2=O)C(C)(Cl)C1O)Oc1ccccc1 +CN(C(=O)C(C)(C)C)C1CCC(C(N)Cc2cc(F)ccc2F)CC1 +COc1cc(CC=Cc2ccccc2C=CC(=O)O)ccc1OCCNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-] +Cc1cc(Nc2ccc(Cl)c(Cl)c2)n2nc(C)nc2n1 +O=S(=O)(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(CCc2ccccc2)CC1 +CC(NC(=O)C1CC2C3CCc4cc(O)ccc4C3CCC2(C)C1O)c1ccccc1 +Cc1cc(Oc2ncccc2OC(F)(F)F)ccc1-c1c(C)c(=O)[nH]c(=O)n1C +CC(C)(C)c1ccc(-c2noc(C(=O)NNC(=S)Nc3ccc(C(F)(F)F)cc3)n2)cc1 +COc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)cn1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(C(=O)C2(C(F)(F)F)CC2)CC1 +COc1ccc2c(=O)c(C)c(-c3ccc(Cc4ccc(OC(F)(F)F)cc4)cc3)[nH]c2c1 +CC1CC(=O)NN=C1c1ccc(NC(=O)c2ccccc2C(F)(F)F)cc1 +CNC(=O)C(NC(=O)c1ccc(-c2cccc(CNC(=O)c3ccnc(Cl)c3)c2)o1)C1CCCCC1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1CCC(C(=O)O)CC1 +COc1ccc(-c2cccc3nc(Nc4ccc(C(=O)O)cc4)nn23)cc1 +NC(=O)NN=Cc1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +CCOc1cc(C(=O)C[n+]2nc(N)n3nc(OC(CC)CC)ccc32)cc(C(C)(C)C)c1OCC +O=C(CCCCCC(NC(=O)c1cc2ccccc2[nH]1)C(=O)NC1(Cc2ccccc2)CCCC1)NO +CCc1cn2c(NC(=O)C3CCCC3)nc(-c3ccccc3)nc2n1 +COc1cc(Nc2ncccc2-c2nc(Nc3ccc4c(c3)OCCO4)n(C)n2)cc(OC)c1 +Nc1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2(Cl)Cl)c(=O)n1 +O=C(NCc1ccccc1)N1CCC(CN2CCC(c3noc4cc(F)ccc34)CC2)CC1 +Nc1nc(-c2ccco2)c2cnn(Cc3c(F)cccc3F)c2n1 +CC(C)(C)C(=O)NC(CCCCN)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 +CC(C)(C)c1n[nH]c2nc(-c3ccccc3)c(C#N)c(-c3ccccc3)c12 +CCC(=NO)c1ccccc1NS(=O)(=O)c1ccc(OC(=O)C(C)(C)C)cc1 +COc1cc2ccn(CCn3cc(NC(=O)c4ncoc4-c4cccc(C)c4)cn3)c2cc1OC +CNc1nn2c(C)cc(CN)nc2c1S(=O)(=O)c1ccccc1 +O=C(Nc1cccc(F)c1)c1ccc2cc(Br)c(C(F)(F)P(=O)(O)O)cc2n1 +CCS(=O)(=O)N1CCN(c2ccc3cc2COCC=CCOCc2cccc(c2)-c2ccnc(n2)N3)CC1 +CN1CCC(c2n[nH]c3ccc(S(=O)(=O)c4ccc(F)cc4)cc23)CC1 +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5c(c4)CCO5)c3c2)C1 +NCCCCC(NC(=O)CN(CC1(c2ccccc2)CCCC1)C(=O)CCc1ccccc1)B(O)O +O=C(c1cccc(OC(F)(F)F)c1)N1CCC(N(C2CC2)S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 +NC(CNC(=O)Nc1cc(S(=O)(=O)O)ccc1F)C(=O)O +NC(=O)c1ccccc1Nc1ccnc(Nc2ccc3ccccc3c2)c1 +CCCOC(=O)c1cccc(NC(=O)COc2ccccc2Cl)c1 +COc1cc(C(=O)NCc2ccc(Cl)cc2F)ccc1-c1cn[nH]c1 +CC(NC(=O)c1ccco1)C(=O)N1CCN(CCCOc2ccc(-c3noc(-c4ccccc4)n3)c(F)c2)CC1 +CCC(Nc1ncnc2[nH]cnc12)c1cc2cccc(C)c2c(=O)n1-c1ccc(F)cc1 +CN(C)CC(=O)NC1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1 +Cc1ncc(C)n2nc(CCc3ccc4cc5c(cc4n3)OC(F)(F)O5)nc12 +Cc1nc(C)c(C(c2ccccc2)c2c[nH]cn2)s1 +Cc1cccc(COc2cc(-n3cnc4ccccc43)sc2C(N)=O)c1 +NS(=O)(=O)Oc1ccc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)cc1F +CC1CN(C(=O)c2ccccc2-n2nccn2)C(Cc2cccc(-c3ncccn3)c2)CO1 +COc1ccc(-c2cncc(C#N)c2Nc2cccc3[nH]ccc23)cc1OC +O=C1CN2Cc3cc(OCCCC(=O)N4CCCC5CCCCC54)ccc3N=C2N1 +CCC(=O)Nc1cc2c(Nc3ccc(Oc4ccc5c(c4)OCO5)cc3)ncnc2cc1OC +CN(C)CCN(C)C(=O)c1cccc(Cc2nnc(O)c3ccccc23)c1 +CN1C(=O)CC(c2ccccc2)C1C(O)c1ccc(-c2ccccc2)s1 +COc1cc(C=C(C(=O)N2CCC=CC2=O)c2ccc(C)cc2)cc(OC)c1OC +CCN(CC(N)=O)c1ccc(Br)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12 +COc1cc(C(CC(=O)c2ccc(C)cc2)Nc2ccc([N+](=O)[O-])cc2)cc(OC)c1OC +O=C1N(c2ccc(C#Cc3ccccc3)cn2)CC2CCCCN12 +COc1ccc2nc(-n3nc4c(c3O)-c3ccccc3CC4)sc2c1 +CC(Cc1ccc2c(=O)ccoc2c1)CN1CCN(c2ccccn2)CC1 +CC(C)(O)CC(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +C=CC(=O)NC1CCN(S(=O)(=O)c2ccc(C(=O)NC3CC3c3ccccc3)cc2)CC1 +COc1ccc(C(=O)NC2C(CC=CCCCC(=O)O)CC3CC2C3(C)C)cc1 +O=S(=O)(c1ccc(Cl)cc1)N(Cc1ccc(-c2cccc(Cl)c2)cc1)Cc1ccccn1 +Cc1cccc(C(=O)NC2(C(=O)O)Cc3ccccc3C2)c1OC1CCC1 +OCCN1CCC2(N3CCCCC3)CC(c3ccc(Cl)cc3)C1C(c1ccc(Cl)cc1)C2 +CCOC(=O)c1cc(C(=N)N)ccc1OCCCCCOc1ccc(C(=N)N)cc1C(N)=O +O=C(NCCCCNc1ccnc2cc(Cl)ccc12)C1CCCC1 +CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3[N+](=O)[O-])cc2)cc1 +Cc1cc2c(cc1O)C1c3ccccc3CCC1N(C)CC2 +CN1CCN(c2c(-c3ccc4nc(NC(=O)c5ccnc(F)c5)cn4n3)c(-c3ccc(F)cc3)nn2C)CC1 +O=C(O)c1ccc(C(=O)C(=Cc2ccc(F)c([N+](=O)[O-])c2)SCc2ccc(Cl)cc2Cl)cc1 +Oc1cc(-c2c(-c3ccncc3)nn3c(-c4ccc(N5CC6CC5CN6)cc4)ccnc23)ccc1F +CC(C)C1NC(=O)C(Cc2ccccc2)NC(=O)C(CC(=O)O)NC(=O)NNC(=O)C(CCCN=C(N)N)NC1=O +CNC1CCC(c2ccc(Cl)c(Cl)c2)c2ccc(S(=O)(=O)NC)cc21 +Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4ccccc4)cc3)ccc12 +CNC(=O)CC(C)(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C1CC1 +O=C(NCCC(=O)N1CC(O)C1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 +COc1ccc(-n2c3cssc-3c(NC(=O)c3ccco3)c2=O)c(OC)c1 +Cc1cnc(-c2ccc3c(c2)CCN(CCCSc2nnc(-c4ccc5[nH]ccc5c4)n2C)CC3)o1 +COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCCC(=O)N(C)C)C(C)C)C(C)C)ccc1OC +O=S(=O)(NCCCN1CCc2ccccc2C1)c1ccc2ccccc2c1 +Cc1ncccc1C#Cc1c(Cl)nc(N)nc1NC1CC(CO)C(O)C1O +N#Cc1cc(C(=O)NN=Cc2cccc3c2ccn3Cc2ccc(C(F)(F)F)cc2)ccc1O +CCCCc1nc2ccc(C)cc2c(=O)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCOC(=O)NC1CCC2C(C1)CC1C(=O)OC(C)C1C2C=Cc1ccc(-c2cccnc2)cn1 +Clc1cccc(Nc2cncc(-c3cncc(NCCCn4cncn4)c3)n2)c1 +CC(C)Oc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C(N)=O +CCOCC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(C(C)(C)C)cc1)C2 +O=C1NC(=O)C(CN2Cc3cc(Cl)ccc3C2=O)(c2ccc(F)cc2)N1 +Cc1c(CN(C)C(=O)C=Cc2cnc3c(c2)NCCC(=O)N3)[nH]c2ccccc12 +COc1cccc(OC)c1CNc1nc(NC2CCCCC2)nc2ccc(Cl)cc12 +CC(=O)OCC(Cc1ccccc1)NC(=O)C(NC(=O)OCC1c2ccccc2-c2ccccc21)C(C)C +O=C(NCC12CCC3(O1)C1Cc4ccc(O)cc4C3(CCN1CC1CC1)C2)c1ccccc1 +Cc1nc(C)c(-c2nnc(SCCCN3CCC4(c5ccc(C(F)(F)F)cc5)CC34)n2C)s1 +COc1cc(OC)c(C(=O)Nc2c[nH]nc2C(=O)NC2CCC(OC)CC2)c(OC)c1 +CC1CCC(CC(=O)N2Cc3ccccc3CC2C(=O)N2CCCC2)CC1 +CC(CCC(O)C(C)(C)O)C1CCC2(C)C3CCC4C(C)C(O)CCC45CC35CCC12C +COc1cc(NC(=O)c2ccccc2F)ccc1-c1nnc(NCCCCN2CCCCC2)o1 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+O=C(c1ccc(F)cc1-c1ncccn1)N1CC2CC(Oc3ccc(C(F)(F)F)cn3)C1C2 +CCc1cc(-c2ccccc2)cc(CC)[n+]1CC(=O)Nc1nccc(Nc2ccc(S(N)(=O)=O)cc2)n1 +CNc1ccc(-c2cc(=O)c3cc(OCCOCCOCCF)ccc3o2)cc1 +COc1c(O)c(CN2CCCC2CO)c2c(c1O)C1OC(CO)C(O)C(O)C1OC2=O +CCCOc1c(CN(C)C(=O)C=Cc2cnc3c(c2)CC2(CCNCC2)C(=O)N3)cccc1OC +O=C(OC1CN2CCC1CC2)c1cc(Cl)cc2nc[nH]c12 +O=C1NC(=O)c2c1c(-c1c(Br)cccc1Br)cc1[nH]c3ccc(O)cc3c21 +COc1cccc(C=C2SC(=Nc3ccccc3)NC2=O)c1OC +NC(=O)c1cnc(Nc2ccc(CCO)cc2)nc1NCc1ccccc1 +CC(C)C1NCCOc2ccccc2C=CCNC(=O)C(Cc2ccccc2)NC(=O)C2(Cc3ccccc3C2)NC1=O +NC(=O)c1ccc2c(c1)nc(NCc1ccccc1Cl)n2CC1CCCCCC1O +CC(C)C1CCC(N2CCC(C(N)=O)(c3ccccc3F)CC2)CC1 +NC(=O)c1cc(I)ccc1NC(=O)C=Cc1ccccc1 +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3ccccc3Cl)c3ccccc32)CC1 +Nc1c2c(nc3c1cc(-c1ccccc1)n3-c1ccccc1)CCCC2 +CCC12CCC(O)CC1=CCC1C2CCC2(C)C(O)CCC12 +CN(C(=O)Cc1cccc2ccccc12)C1CCC2(CCCO2)CC1N1CCCC1 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(CN5CCC(O)C5)CC4)cc2)CC3)cc1 +COc1ccc(OC)c(C(=O)CCCCN2CCC3(CC2)NC(=O)NC3=O)c1 +CC(C)N1C2C=C(c3cnc(NCc4ccc5c(c4)OCC5)c(C(=O)NCC4COc5ccccc5O4)c3)CC1CC2 +O=C(NC1CCC(CCN2CCC(c3cccc4c3CCO4)CC2)CC1)C1(O)CC1 +CCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OC +CCCC(CC(=O)O)n1ccc2cc(NC(=O)Cc3ccc4c(n3)NCCC4)ccc21 +Cc1c(F)cc(C(=O)NC2CC2)cc1-c1cc2cnn(-c3c(F)cccc3F)c2n(C)c1=O +NC1CN(c2nccc(-c3ccccc3)n2)CC1c1ccc(Cl)cc1Cl +CN(C)Cc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 +CN1C(=O)C(c2ccc(C#Cc3ccccc3)nn2)CC1(C)C +O=C(O)CCNC(=O)C1CCCCN(C(=O)CCC2CCNCC2)C1 +COc1ccc(-c2ccc[nH]2)c(C(=O)c2cc(OC)c(OC)c(OC)c2)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c4c(ccc3nc2-1)OCN(c1ccc(C)cc1)C4 +CC(C)(NC(=O)c1ccc2c(=O)c3ccccc3[nH]c2c1)c1cccnc1 +Brc1sc2nccc(N3CCC(COCCN4CCCC4)CC3)c2c1-c1ccccc1 +CCCNCC(=O)Nc1c(C)[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c1C +COc1cc2c(cc1OC)-c1c(-c3cccc(Br)c3)ncn1CC2 +COc1c(CNC2CCC(NS(C)(=O)=O)CC2)cc(-c2ccc[nH]c2=O)cc1C(C)(C)C +CNC(=O)c1ccc(-c2cc3c(NC4CC5CN(C(=O)C(C)(C)O)CC5C4C)c(C(N)=O)cnn3c2)cn1 +CS(=O)(=O)c1ccc(-c2cccc(-n3cc(C(=O)NC4CC4)c(=O)c4cccnc43)c2)cn1 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+COc1cc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)ccn1 +COc1cc(OC)c2c3c(n(S(=O)(=O)c4ccc(N)cc4)c2c1)CCCC3 +Cc1nn(C)cc1-c1cccc2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC(F)(F)F)cc12 +C#CCOc1cc2c(Nc3cccc(Cl)c3)ncnc2cc1OC +Cc1cc(C)c(CNC(=O)c2cc(Br)nc3c2cnn3C(C)C)c(=O)[nH]1 +N=C(N)c1cccc(COc2c(Cl)cc(C(=N)N)cc2Cl)c1 +COC(=O)C1C(c2ccccc2)CC2CCC1N2CC#CCF +Cc1c(Cc2c(F)cccc2Cl)nc(SCC(=O)c2ccc(F)cc2)[nH]c1=O +O=C(CN1CCC(NC(=O)c2ccccc2)C1)NC1CCc2cc(F)ccc2C1Cc1cccnc1 +O=C1NC(=O)C(c2ccc(Oc3ccccc3)cc2)(N(CCO[N+](=O)[O-])CCO[N+](=O)[O-])C(=O)N1 +Cc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)NS(=O)(=O)C1CC1)n2Cc1ccccc1F +CN1CCc2c(c3cc(C(C)(C)C)ccc3n2Cc2ccc(C(=O)NO)cc2)C1 +Cc1[nH]c(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)OC(=O)NC2CCCCC2)nc1C(=O)O +Cn1cc(-c2cc(NS(C)(=O)=O)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +COC1Cc2ccccc2C2(CCCN(CCCc3ccccc3)C2)O1 +Cc1ccc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NC2CCN(CC(C)(C)C)CC2(C)C)cc1 +CN(C)CCCNC(=O)c1ccc2c(c1)CC(c1nc3ccc(-c4ccnc(N)n4)cc3[nH]1)CO2 +O=C1c2ccccc2CCCC1CCN1CCC(Oc2ccccc2)CC1 +O=C1COc2ccccc2N1CCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1 +O=C(O)c1cccc2c3c(n(Cc4ccc(F)cc4)c12)CCCC3 +COCc1cc(Nc2cccc(Cl)c2)nc(-c2ccccn2)n1 +COc1cc(Nc2c(C#N)cnc3cc4c(cc23)ncn4CCN2CCOCC2)c(C)cc1Cl +Cc1cccc(OCC(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)c1 +Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4cccnc4)c3Cl)c2n1 +Oc1c2c(nc3cc(-c4ccc(Br)cc4)nn13)CCCC2 +CCC(O)(c1cn(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)cn1)C(F)(F)F +Cc1nnc(-c2ccc(-c3cc(NC(=O)c4ccc(CN5CCN(C)CC5)cc4)ccc3C)c(C)c2)o1 +CNC(=O)c1cc(-c2ccnc(C)c2C#Cc2ccc(C)nc2)ccc1Cl +CN(C)CCNC(=O)c1ccc(-c2nn(C)c(=NC3CCCCC3)s2)cc1 +FC(F)(F)c1ccccc1-c1cc(Cl)c2[nH]c(C3=NOC4(CCCCC4)C3)nc2c1 +CC(C)NC(=O)c1cn(-c2cccc(Br)c2)c2ncccc2c1=O +Cc1nc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)cc(N2CCC(CO)CC2)n1 +O=C(c1ccco1)N1CCN(c2cnn(CCN3CCN(c4ccccc4Cl)CC3)c(=O)c2Cl)CC1 +C(#Cc1ccccc1)CNC1CCN(Cc2ccccc2)CC1 +Cc1cc2ncc(-c3ccc4cc(CCN5CCCC5C)ccc4n3)c(C)n2n1 +COc1ccccc1N1CCN(CCSc2nc3ccccc3[nH]2)CC1 +COc1ccc2c(c1)[n+]([O-])nc(NCOC(C)c1ccccc1)[n+]2[O-] +O=C(NC1CCCC1Nc1cnc(C(F)(F)F)cn1)c1ccccc1-n1nccn1 +O=C1C(N2CCC(c3ccc(O)cc3)CC2)CCN1Cc1ccc(OC(F)F)cc1 +C#CCOc1cc(-n2nnc3c(cnn3C)c2=O)c(F)cc1Cl +Cc1cccc2cc(C(C)Nc3nc(Cl)nc4[nH]cnc34)n(-c3ccccc3)c(=O)c12 +O=C(Nc1ccc(C(=O)N2CCN(CCOCCO)CC2)cc1)N1Cc2cccnc2C1 +CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1C#N +O=C(O)c1ccc(C2CCCN2C(=O)C(Nc2ccccc2F)c2cc3ccccc3s2)cc1 +CC1CCN(C(=O)c2coc(-c3ccc(CNC(=O)Cc4cccs4)cc3)n2)CC1 +COc1ccc(CN2CCN(C3CCC(O)(c4ccc5c(c4)OCO5)CC3)CC2)cc1 +Cc1nn(-c2cccc([N+](=O)[O-])c2)c2oc3cc(O)ccc3c(=O)c12 +CN1CCN(c2cc(N3Cc4ccccc4C3)nc(N)n2)CC1 +Cc1ccc(CNC(=O)c2[nH]c3ccc(Cl)cc3c2S(=O)(=O)c2cc(C)cc(C)c2)cc1 +CC(Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CN2CCS(=O)(=O)CC2)cc1Cl +COc1cc2c(N3CCN(C(S)=Nc4ccc(-c5ccccn5)cc4)CC3)c(C#N)cnc2cc1OCCCN1CCCCC1 +NS(=O)(=O)c1cccc(Nc2nccc(-c3ccnc(N4CCCCC4)c3)n2)c1 +CS(=O)(=O)N(CC(=O)Nc1ccccc1)c1ccccc1Cl +O=C(NN1CCCC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1Cc1cc(C3CC3)ccc1-2 +Cc1ccc2c3c(ccc2n1)OCC(CN1CCN(c2ccc4cc(OC(F)(F)F)ccc4n2)CC1)O3 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+CC(C)(C)NC(=O)Cc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 +O=C(NC1CCN(C2CCNCC2)C1=O)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CC1CN(C(=O)c2ccc(NC(=O)c3cc(OC(C)c4c(Cl)ccc(F)c4Cl)c(N)nn3)cc2)CC(C)N1 +CN1C2=NC3C=CC=CC3C2=C(N2CCOCC2)c2ccccc21 +CN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCS(=O)(=O)C2)cn1 +CC(C)c1[nH]nc(OC2OC(CO)C(O)C(O)C2O)c1Cc1ccc(CCCCC(N)=O)cc1 +CCCc1cc(N)c2cc(NCCCc3ccc(C(F)(F)F)cc3)ccc2n1 +c1ccc(CCN=C2CCCc3c2[nH]c2ccccc32)cc1 +COc1cnc(C(=O)Nc2ccc3c(c2)C2(CCSC(N)=N2)c2cc(C4=CCCOC4)nc(F)c2O3)cn1 +COc1ccccc1C(=O)c1cnc(NC2CCN(C(=O)Nc3cccc(F)c3)CC2)nc1N +CC#Cc1ccc2c(c1)C1CCCN(C(=O)c3ccc4nc[nH]c4c3)C1C2 +CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3)CC2)C(c2ccc(F)c(F)c2)CC(=O)N1 +CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]ccc23)c1 +COC(=O)C1(O)CC2OC1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 +COc1ccc2c(c1)CCCC2CCCCN1CCCCC1(C)C +CC(F)(F)c1nn2cc(-c3cc4c(Cl)cc(Cl)cc4o3)nc2s1 +CC(C)(CCCC(=O)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1)N1CCC(c2nc(-c3ccccn3)no2)CC1 +O=C(NC1(c2ccccn2)CC1)c1nn(-c2ccc(C(F)(F)F)cc2Cl)c2c1CCCC2=Cc1ccc(Cl)s1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCCCn1cnc2c(N)ncnc21 +O=C(Nc1ccc(SC(F)(F)Cl)cc1)c1cnc(N2CCC(O)C2)c(-c2cncc(F)c2)c1 +Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NCC2CC2)cn1 +CCOc1cncc(C2=CCC3C4CCC5COCCCC5(C)C4CCC23C)c1 +CC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCCC2C(O)CCc1ccccc1 +CCOC(CC(=O)O)c1ccc(OC2Cc3ccccc3C2)cc1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(C)(C)Oc4ccc(F)cc43)cc21 +CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(NCCCc3ccccc3)c3ccccc23)CC1 +Cc1ccc(C=Cc2cccc(C(CCc3ccccc3C(C)(C)O)SCC3(CC(=O)O)CC3)c2)nc1C(C)C +CC12CCC3c4ccc(O)cc4CCC3C1CCC2(O)C#Cc1cccc2c(=O)cc(-c3ccccc3)oc12 +CCOC(C)(C)c1cnc2n1CC(c1cccc(F)c1F)CCC2NC(=O)N1CCC2(CC1)OC(=O)Nc1ncccc12 +COC1CCC2(CC1)Cc1ccc(-c3cccnn3)cc1C21N=C(N)N(C)O1 +CCC1CC(=O)NN=C1c1ccc2nc(-c3cccc(OCCN4CC(C)OC(C)C4)c3)oc2c1 +O=C(c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)N1CCN(C(=O)N2CCOCC2)CC1 +Cc1n[nH]cc1-c1cc2nc(CN3CCCC3)[nH]c(=O)c2s1 +Cc1cc(C)c(-c2[nH]c(C3CCOCC3)nc2C)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +O=P(c1ccccc1)(c1ccccc1)N(Cc1ccccn1)c1cccnc1 +O=C(c1cc2cc(F)ccc2[nH]1)c1cc2cc(OCCN3CCCCC3)ccc2[nH]1 +CNC(NCCNCc1ccc(CN(C)C)o1)=C(C#N)C#N +COc1cc2nc(CO)c(CO)c(-c3ccnc(-n4nc(-c5cccnc5)c5ccccc5c4=O)c3)c2cc1OC +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(NC3CCOC3)nc12 +CC(=O)N1C(=O)Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)cc3)cc21 +Cc1noc(C)c1Cn1cc(NC(=O)c2ccccn2)cn1 +CC(=O)OC1CC(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C21 +CS(=O)(=O)c1ccc(N(c2ccccc2)c2nc(-c3ccc(F)cc3)c(CC(=O)O)s2)cc1 +CCC1CN(c2ccc(C(F)(F)F)cc2C#N)c2ccc(S(=O)(=O)Nc3nccs3)cc2O1 +CC(C)COc1cc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n(C2CCCC2)c1=O +Cc1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCC4)CC3)c2)c1 +CCNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 +COCCCc1cc(CN(C(=O)C2CNCCC2c2ccn(C)c(=O)c2)C2CC2)c2ccccc2n1 +N#Cc1cnc(N2CCC(NC(c3cccnc3)c3ccc(Cl)cc3F)CC2)s1 +CC(C)Cn1c(=O)c2[nH]c(Cc3ccccc3)nc2n(Cc2ccco2)c1=O +CN(c1nc2cc(F)ccc2o1)C1CCc2c(CC(=O)O)c3cc(Cl)ccc3n2C1 +CCCc1c2c(cc(OC)c1C(=O)OC)C1(C)CCCC(C)(C(=O)OC)C1C=C2 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+O=C(NCC(c1cccnc1)N1CCN(c2ccccc2)CC1)Oc1ccccc1 +C=C(C)CNc1ccnc2sc3c(=O)n(-c4ccc(Br)cc4)cnc3c12 +CC(C)C(C(=O)NC1Cc2ccccc2C1O)C(O)C(O)C(CC1CCCCC1)NC(=O)c1ccccc1OCOc1ccccc1 +Cc1cc2sc3ccc(C#CC4(O)CCCCC4)cc3c(=O)c2cc1C +CN1CCC(c2cc(C(F)(F)F)ccc2-c2cccc3cc(S(=O)(=O)Nc4ccncn4)ccc23)CC1 +CC(C)(C=NOCC(=O)O)Cc1c(SC(C)(C)C)c2cc(OCc3cccc(Cl)n3)ccc2n1Cc1ccc(Cl)cc1 +CCOc1ccc(S(=O)(=O)N2CCCNCC2)cc1-c1nnc2c(n1)c(C)nn2C +COc1cc2c(cc1O)CCC1C2CCC2(C)C(c3ccc4cnccc4c3)CCC12 +CN(Cc1ccc2[nH]cnc2c1Cl)c1nccc(Nc2cc(C3CC3)[nH]n2)n1 +COc1ccc(C(=O)Nc2ccc(C)c(Nc3ncnc4cnc(N(C)C)nc34)c2)cc1C(F)(F)F +CN(CC1CCOCC1)c1cccc(-c2cc(NC3CCC(N)CC3)ncc2Cl)n1 +N#CC(Cc1ccc(N2CCN(c3ccccc3)CC2)cc1F)NC(=O)C1NC2CCC1C2 +CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(c2ccncc2)CC1 +Cc1ccc2cccc(OCc3c(Cl)ccc(S(=O)(=O)NC(C)(C)C(=O)N4CCN(CCCCCCN)CC4)c3Cl)c2n1 +COC(=O)N(NC(=O)c1c(OC)c(-c2ccccc2)nc2ccc(F)cc12)c1ccccc1 +Cc1c(C(O)CN2CCC3(CC2)CCN(c2ccc(C#N)cc2)C3)ccc2c1COC2=O +Cc1cc(C)cc(-c2cnc(-c3cccnc3)c(C(=O)NCc3ccc(C(F)(F)F)c(F)c3)c2)c1 +CN(C)c1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +COCCOc1cc(-c2ccc3nc(NC(C)=O)cn3n2)cnc1N +CC(c1cc(=O)[nH]c(N(C)C)n1)c1c(F)cccc1F +CCCCN(c1sc2ccccc2c1Cl)S(=O)(=O)c1ccc(N(C)C)cc1 +CCCCn1c(=O)c2cc(N)ccc2c2cnc3cc4c(cc3c21)OCO4 +CCCNC(=O)c1cn(C2CCCC(OC3OC(CO)C(O)C(n4cc(C(=O)NCCC)nn4)C3O)C2O)nn1 +C=CC(=O)N1CCCC(c2c(Cl)c(-c3ccc(Oc4cccc(Cl)c4)c(OC)c3)c3c(N)ncnn23)C1 +CN(C)CCCn1nc(C2=C(c3cn(-c4ccc5ccccc5c4)c4ccccc34)C(=O)NC2=O)c2ccccc21 +CC(C)NC(=O)N(C1CCCCCCC1)C1CCN(CCCOc2ccc(F)cc2)CC1 +CCOC(=O)CN1C(=O)C(NC(=O)c2cc3ccccc3[nH]2)CCc2ccccc21 +CCP(=O)(CC)c1ccccc1Nc1nc(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)cc2OC)ncc1Cl +O=C(Nc1ccn2cc(-c3cccc(F)c3)nc2c1)N1CCCC1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCCS(=O)(=O)CC(C)C +CCS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccccc3)cc2s1 +N#Cc1ccn2cc(C(=O)NCc3cccc(C(=O)Nc4nc5c(s4)CC(N4CCOCC4)CC5)c3)nc2c1 +COCCOc1ccc(C(C)NC(=O)n2sc3ncccc3c2=O)cc1OC +CCN(C(=O)C(C)C1(O)CCN(CCc2ccccc2Cl)CC1)c1ccccc1OC +CCN(CC)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +Cc1cc(C)nc(SCc2ccc(C(=O)NNC=C3C=CC=C(O)C3=O)cc2)n1 +COc1ccc(N2C(=O)C(C)(C)C2c2ccc(F)cc2)cc1 +CC(C)(C)n1nc(-c2cnc3cc(OC(F)(F)F)ccc3c2)c(C(N)=O)c1N +Cc1cncc(-c2cc3c(cn2)cnn3-c2cc(N3CCCC(N)C3)c(=O)n(C)c2)n1 +Nc1nc(O)c2c(Cl)c(NCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)ccc2n1 +O=C(c1cccc(O)c1)c1ccc(-c2cccc(O)c2)s1 +Fc1ccc(C2(CCCSc3nnc4c(n3)[nH]c3ccccc34)OCCO2)cc1 +OC1CCN(Cc2cccc(I)c2)CC1N1CCC2(CCCc3ccccc32)CC1 +CC(=O)NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21 +CCOC(=O)c1cc2ccc(OC(=O)c3ccco3)cc2oc1=O +NCc1ccc(CN(CC2Cc3ccccc3CN2)C2CCCc3cccnc32)cc1 +CCCn1c(=S)sc2c1ncn1nc(-c3ccco3)nc21 +Cn1nccc1-c1ccc(I)cc1Oc1ccc(S(=O)(=O)Nc2nccs2)cc1C#N +CCN(CC)c1nn2c(=N)n(CC(=O)c3cc(OCCCO)c(OC)c(C(C)(C)C)c3)nc2c(C)c1C +N#Cc1ccc(N(CC(=O)N2CCC(CN)CC2)Cc2ccc(C(N)=O)cc2)cc1 +NC(=O)c1nc(Nc2ccc3ccccc3c2)sc1NC(=O)C#CCCCn1ccnc1 +COc1cc(-c2ncoc2-c2ccc(OC)c3ncn(CCO)c23)cc(OC)c1OC +CN(Cc1ccc(C#N)cc1)Cc1ccc(COc2ccc3ccc(=O)oc3c2)cc1 +O=C(Nc1cc2ccc(N3CCC(O)C3)cc2cn1)C1CC1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C(C)CNCc1c(F)cccc1F +COc1ccccc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +Nc1ncc(-c2cccc(-c3cnn(CC(F)(F)F)c3)c2)nc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 +COc1ccc(Nc2cc3nc4ccccc4n(-c4ccccc4)c-3cc2=NCCCCC23CCCCN2CCCC3)cn1 +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C12CN(c1cnc(C(=O)O)cn1)CC2c1ccc(C#N)cc1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C=Cc1cccnc1)CC2 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(Nc4cnc(N5CCNCC5)nc4)c3c2)cc(Cl)c1O +CCC(C(=O)Nc1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2C(=O)O)cc1)c1ccccc1 +COc1cc(NC(S)=NC(C)c2ccc(F)cc2)ccc1NC(=O)c1ccccc1F +CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3c(ccn3CCc3ccc(C#N)cc3)c2)cc1 +COc1ccc([P+](CCCCCCCCCCN2C(=O)c3ccccc3C2=O)(c2ccc(OC)cc2)c2ccc(OC)cc2)cc1 +CN1CC(CNC(=O)c2cc(NC(=O)c3cc(-c4ncccc4F)ccc3Cl)n(-c3ccccc3)n2)OCC1=O +CC(NC1CCN(c2ccc(S(=O)(=O)NCCN(C)C)cc2)C1)c1cccc2ccccc12 +O=C(Oc1cccc(-c2ccccc2)c1)N1CCN2CCC1CC2 +CCCCC(Sc1ccc(OCCCOc2ccccc2)cc1)C(=O)O +CN(C)c1nc(NCC2CCC(CN(C)S(=O)(=O)c3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12 +CN(C)CCCc1c[nH]c2ccc(N=C(N)c3cccs3)cc12 +O=C1Nc2c(C(F)(F)F)cccc2C1(c1ccc(O)cc1)C1CCCCCC1 +CCCCC(C)C1CC(=O)NC(Cc2ccccc2)C(=O)NC(C)C(=O)NC(Cc2ccccc2)C(=O)O1 +Cc1nc(C2CC2c2nc3ccccc3n2CC2CCCCO2)cc(-n2nc(C)nc2C)n1 +Cc1cc(N2CCN(C3CNC(C(=O)N4CCSC4)C3)CC2)n(-c2cccnc2)n1 +O=C(CCNC(=O)c1nc2ccccc2n1Cc1ccccc1)Nc1ccc2nc[nH]c2c1 +CC(C)NCc1cccc(C=Cc2nc3ccc(F)cc3c(=O)n2-c2ccccc2Cl)n1 +Cc1ccc2sc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3)nc2c1C +CCCCC#Cc1nc(N)c2ncn(C3OC(CSCCC)C(O)C3O)c2n1 +CC(C)OC(=O)N1CCC(Oc2ncnc3c2CCN3c2ccc(C#N)c(F)c2)CC1 +Fc1ccc(-c2c(-c3ccncc3)n(CCN3CCOCC3)c3cccnc23)cc1 +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)CC(F)(F)C1 +O=C1CCc2cc(OCCCN3CCN(c4cccc5sccc45)CC3)cc(F)c2N1 +CCNC(=O)Nc1ccc(-c2nc(N3CCOCC3C)c3c(n2)C(C)(CC2CC2)OC3)cc1 +CCCC(c1cccc(NS(=O)(=O)c2ccc(F)cc2)c1)c1c(O)c2c(oc1=O)CCCCCC2 +COc1cc(C(N)=O)ccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1NC1CCC(N)CC1 +CCON=C(C)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +Cc1cc(OC2OC(CO)C(O)C(O)C2O)c2c(CCc3ccc4c(c3)CCO4)n[nH]c2c1 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+CC(C)c1ccc(C(SCC(N)C(=O)O)(c2ccccc2)c2ccccc2)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2ccc(OC(F)F)cc2)cc1 +CC(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(=O)O +COCC1OC(n2cc(I)c3c(Cl)ncnc32)C(O)C1O +COc1ccc(CC(C)Nc2ccncc2S(=O)(=O)NC(Cc2ccc(N)cc2)C(=O)N2CCC(CCF)CC2)cc1 +CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1ccccn1 +CCCS(=O)(=O)Nc1cccc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +COc1nc(OC2CCCCC2C)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +COc1ccc(Nc2c3ccccc3nc3c(C)cccc23)cc1NC(=O)Nc1ccc(N(CCCl)CCCl)cc1 +CCC(C)N1C(=O)C2(N=C1N)c1cc(C#CC3CC3)ccc1CC21CCC(OC)CC1 +CC=C(C)C(=O)OC(C)(C)C1Cc2cc3ccc(=O)oc3cc2O1 +CN1CCC(n2cc(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c3ccccc32)CC1 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4cccc(Cl)c4)no3)ccc21 +O=C(OCc1cccs1)c1cnn2c1n[n+]([O-])c1ccc(-c3ccco3)cc12 +Cc1nc2c3cccnc3nn2c(C)c1CCC(=O)Nc1ccccc1F +CCCCc1nc(Cl)c(C(=O)NC(Cc2ccccc2)C(=O)OC)n1C +CCc1nc(NC(=O)c2ccccn2)sc1S(=O)(=O)Cc1cccc(Cl)c1F +CC(C)Nc1cc(-n2ccc3cc(CNC(=O)Cc4ccccc4)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +COc1cccc(O)c1C(=O)N1CCC(=CC(=O)NC2CCN(Cc3ccc4cc(F)ccc4c3)C2)CC1 +Clc1ccc(N2CCCN(CCCCc3nc4ccccc4s3)CC2)cc1 +CN(C)CC(=O)N1CCC(Oc2ccc(-c3n[nH]c4ccc(C(=O)NC(c5ccccc5)C5CC5)cc34)cc2)CC1 +CC(C)C(C(=O)Nc1ccc2[nH]nc(-c3cccc(S(N)(=O)=O)c3)c2c1)c1ccccc1 +CCCCCCCn1c(=O)c(C(=O)Nc2cnccn2)c(O)c2ccccc21 +Cc1cc(C)cc(-c2cnc3cc(Cl)c(C(=O)Nc4ccncn4)cc3c2OCCC2CCCCN2)c1 +CN(c1ccc2ccccc2c1)c1ccc2nc(N)nc(N)c2n1 +CCc1nc(Cc2ccccc2)sc1C1CCN(CC2CN(C(CC(C)C)C(=O)O)CC2c2ccccc2)CC1 +COc1cccc(CCCc2nc(N)c3nn(-c4ccccc4)cc3n2)c1 +CCCCCC1=NN(C(=O)NC2CCCCC2)CC1c1ccccc1 +Fc1ccc(OCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)n(-c2cccc(CN)c2)n1 +Cc1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1NC(=O)c1ccc2nc(OCCCN3CCCCC3)ccc2c1 +NS(=O)(=O)c1nc2ccc(NC(=O)CNCCNCC(=O)O)cc2s1 +O=C(NCC1(N2CCCC2)CCCC1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +Nc1n[nH]c2cccc(-c3ccc4c(C(=O)Nc5cccc(Br)c5)cccc4c3)c12 +Cc1ccc(Oc2ccc(Nc3ncnc4cccc(OC(C)C(=O)N5CCOCC5)c34)cc2C)cn1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccc(C#N)cc3)o2)C(C)O)c(C)c1Cl +Cc1nc(NC(=O)c2ccc(NC(=O)CC(C)(C)C)cc2)sc1C +CCCC(Cc1ccc(C(=O)NCCC(=O)O)cc1)C(=O)c1cc2cc(Cl)ccc2n1-c1ccc(Cl)c(C(F)(F)F)c1 +COc1cccc2c1-c1ccc(NC(C)=O)cc1C(c1ccccc1)O2 +CC12COS(=O)(=O)CC1=C(c1ccccc1Br)C(=O)O2 +CCCCCCCCc1ccc(OCC(=O)Cn2ccc3cc(S(N)(=O)=O)ccc32)cc1 +c1ccc(Nc2nc3cc(-c4nnn[nH]4)ccc3c3cnccc23)cc1 +CCCCN(C)C(=O)C(NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1)c1ccccc1 +Cc1nc(N)nc(-c2c(Nc3cc[nH]n3)nc3ccc(-c4ccncc4)cn23)n1 +COc1ccc(CN2CCC(NC(=O)CNC(=O)c3cccc(C(F)(F)F)c3)C2)cc1 +O=c1cc(Cn2ccnc2)c2ccc(Oc3ccccc3)cc2o1 +COc1ccc2c(c1)CCCC2Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O +Cc1nc(OCc2ccc3ccccc3n2)cc(-n2nc(C)nc2Cc2nc(C)sc2C)n1 +COc1ccccc1N1CCN(CCCCNC(=O)Oc2ccc(-c3ccccc3)cc2)CC1 +CN(C)CCCCN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +Nc1ccc2[nH]c(-c3cc(CC(=O)O)cc(-c4cccc([N+](=O)[O-])c4)c3O)cc2n1 +O=C(OC1C[N+]2(CCc3ccccc3)CCC1CC2)N(Cc1ccccc1)c1ccccc1 +Nc1nc(NCc2ccccc2)nc(-c2ccc(CC(N)C(=O)O)cc2)n1 +COc1cccc(NCc2nc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)[nH]2)c1 +Fc1cnc(Cl)nc1NCc1ccc(CNc2ccnc(NCCN3CCOCC3)n2)cc1 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cc2)cc1C#Cc1ccc(N)nn1 +COCCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(CCN5CCOCC5)c4)cc2)CC3)n1 +O=C(O)c1cncc(C2CC2c2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C3CC3)cc2Cl)c1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCn4c(cnc4C)C3)[nH]c12 +O=C(NCC1CCCCO1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +NC(=O)C1CCCN1C(=O)CCCNC(=O)c1ccc(F)cc1 +CC1Nc2ccc(-c3ccc(C#N)s3)cc2C(C)(C)O1 +CC(=O)c1ccc(Oc2ccc(-c3ccc(-c4ccccc4Cl)n3CC(=O)NC(=N)N)cc2)cc1 +NC1=NC(c2ccc(OC(F)(F)F)cc2)(c2cccc(-c3cccnc3F)c2)C2=NCCN12 +CN(C)c1cc(N2CCNCC2)ccc1S(=O)(=O)c1ccccc1 +CC(C)CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)C(O)C(O)C1O +CCNC(=O)c1cn2cc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)c2n1 +Nc1ncnc2c1c(-c1ccc3ncccc3c1)nn2CC1CCNCC1 +CC(C)Oc1ccc(-c2cc(C(=O)O)nn2-c2ccc(Oc3ccccc3)cc2)cc1 +Cc1ccc(CSCC(CO)NC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cc1 +Nc1cccc(-c2cc(-c3c(-c4ccc(O)cc4)n[nH]c3N)ccc2O)c1 +CN1C2COCC1CC(OC(=O)c1cn(CC(F)F)c3ncccc13)C2 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+CCOc1cc(C(=O)Nc2ncc(C)s2)ccc1-c1nc(C2CCC3CCC(=O)N3C2)n2c(Cl)cnc(N)c12 +CC(C)C(NC1=NS(=O)(=O)N=C1Nc1cccc(C(=O)N(C)C)c1O)c1cccc(F)c1 +O=C(NCC(c1cnc(C(F)(F)F)nc1)C1CCOCC1)c1c(F)cccc1Cl +COc1ccc2c(c1)CCCC2CCCCN1CCC(C)(C)CC1 +Cc1ccccc1C(CC(=O)O)NC(=O)c1cc(=O)n(-c2ccccc2)[nH]1 +Cc1nc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(N)c3ccccc3)c2=O)cs1 +N=C(N)NCCCC(N)COP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1O +CC(C)(C)N1CCC(Oc2cc(-c3ccc(F)cc3Cl)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c2)CC1 +Cc1onc(-c2ccccc2Cl)c1C(=O)N(C)c1cccc(F)c1 +O=C(Nc1cc(-c2ccccn2)nn1CC(F)(F)F)c1nc(C2CC2)ccc1Nc1cncnc1 +CC#CC(CC(=O)O)c1ccc(OCc2cccc(CN(C)Cc3ccsc3)c2)cc1 +COc1cc(C)c(C(=O)NS(=O)(=O)c2ccccc2)cc1-c1ccc(C#CCO)s1 +O=C(c1ccc(F)cc1)C1CCN(CCc2ccc(I)cc2)CC1 +CSc1ccccc1Nc1nc(N2CCNCC2)nc2c(NCC3CC3)ncnc12 +CNC(=O)c1c(NC(=O)c2nc(C(C)C)cnc2Nc2cncnc2)cnn1C +Cc1cc(C)cc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(C)cc2Br)c1 +O=C1Nc2cc(-c3ccc(O)cc3)ccc2C1=Cc1ccc(C(=O)NCCN2CCCC2)[se]1 +CCNc1nc2ccccn2c(=N)c1S(=O)(=O)c1ccccc1 +COC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1ccccc1 +CC(c1cc2c3c(c1)CCN3C(=O)CC2)(n1ccnc1)n1ccnc1 +CC1CN2c3c(cc4c(C(=O)NCC(F)F)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CCn1c(O)cn(-c2ccc(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)cc2)c1=O +NC(CC(=O)N1CCc2c(C3CC3)n[nH]c2C1)Cc1cc(F)ccc1F +NCCCC(Cc1cn(C2CCC(Oc3ccccc3)CC2)cn1)C(=O)O +CCNC(=O)c1noc2c1CN(C(=O)c1cc(C(C)C)c(OC(C)=O)cc1OC(C)=O)CC2 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(OC(F)(F)F)c(F)c2)c1 +CN1C(=O)C(c2ncc(C#Cc3ccc(F)cc3)cn2)CCC1(C)C +O=C(c1cccc2ccccc12)N1CCC2(CC1)NC(=O)N(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C2=O +Cn1c(C(=O)NCC(F)(F)F)nc2c(N3CCC(n4c(=O)[nH]c5ncccc54)CC3)ncnc21 +COc1ccc(F)c(CN2CCN(C3CCC(O)(c4ccc5c(c4)OCO5)CC3)CC2)c1 +CC(C)c1cccc(C(C)C)c1NC(=O)CC(=O)CC(c1ccccc1)c1ccccc1 +Oc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CCCCc1nc(C)n(Cc2ccccc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCCC(NC(=O)c1nccs1)c1cnc(Nc2cnc(C)nc2)c(Cl)c1 +CC=C1C(O)CC2C3CCC4CC(N5CCCC5)CCC4(C)C3CCC12C +Cc1ncccc1N1CC(C(=O)NCc2ccc(F)c(F)c2Cl)N(C)C1=O +CCc1c2c(n(C)c1CC)CCCC2=NOC(=O)Nc1ccccc1 +CC1OC(=O)C2(N)CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4-c4nnn[nH]4)cn3)C12 +Cc1cccc(-c2nc3ccc(C)cn3c2NCc2ccccc2)c1 +Fc1ccc(Oc2cncc3sc(-c4nnn[nH]4)cc23)cc1 +CNc1cnc(-c2ccc(C3(c4noc(-c5cnn(C6COC6)c5)n4)CCC3)cn2)cn1 +O=C1NCC2(CCNCC2)c2[nH]c(-c3ccnc(-c4cnc5ccccc5c4)n3)cc21 +Cc1cc(C)nc(SCC(=O)c2ccc(S(N)(=O)=O)cc2)n1 +O=c1cc(Cn2ccnc2)c2ccc(OCc3cccc(OC(F)(F)F)c3)cc2o1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CCC2)C1c1ccc(C#N)cc1C1=CCNCC1 +CC(C)(C)C(=O)OCOP(=O)(CC=CCn1cnc2c(=O)[nH]c(N)nc21)OCOC(=O)C(C)(C)C +CC(C)Oc1nc(-c2cccnc2)nc2c1CN(c1nc3ccccc3o1)CC2 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C4COC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1C +COc1ccc(-c2nnnn2-c2cc(OC)c(OC)c(OC)c2)cc1F +NC(=O)c1cc(N2CCOC(C(N)=O)C2)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +CCC1CN(CC(F)(F)F)c2cc3c(C(F)(F)F)cc(=O)[nH]c3cc2O1 +O=C(NCCCNc1nc2ccccc2[nH]1)c1cccc(OC(F)(F)F)c1 +COc1ccc(C(Cc2ccncc2)c2ccc(NS(=O)(=O)Cc3ccccc3)cc2)cc1OC1CCCC1 +O=C1c2ccccc2C(=O)c2c1c(O)c1[nH]cc(CNC3CCNC3)c1c2O +CC1(C)CC(=O)C2=C(C1)Nc1c(O)cccc1N(C(=O)c1cscn1)C2c1ccc(OCc2ccccc2)cc1F +C[N+]1(C)C2CCC1CC(CC(O)(c1cccs1)c1cccs1)C2 +Cc1cc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)ccc1Oc1ccnc(NC(=O)C2CC2)c1 +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCCCCCNC(=O)C2CN(C)CCC2c2ccc(Cl)cc2)C1 +COc1ccc(CN2C(=O)C(=CC=Cc3ccc([N+](=O)[O-])cc3)c3ccccc32)cc1 +C#CCN(C)C(=O)CC1CN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CCN1C(=O)c1ccc(C2=NCCN2C)cc1 +COc1cccc(-n2cnc3c(NN=Cc4ccncc4)ncnc32)c1 +CC1c2cc(Cc3ccccc3)c(-c3ccccc3)n2CCN1Cc1cnc(N)nc1N +NS(=O)(=O)c1nnc(NS(=O)(=O)c2cccc(C(=O)O)c2)s1 +CCOC(=O)c1nnn(-c2cccc([N+](=O)[O-])c2)c1C(O)C(O)C(C)O +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCNCC1 +CCc1cc2c(cc1F)c(C(N)=O)c(-c1ccc(NS(=O)(=O)C(C)C)cc1)n2C1CCCC1 +CC(O)C(C(=O)NO)N1Cc2cc(C#Cc3cccc(-c4ccccc4)c3)ccc2C1=O +C=C(C)n1c(=O)n(Cc2nc3ccccc3n2CCCC#N)c2ncccc21 +CN1CCN(S(=O)(=O)c2cc(C(=O)Nc3cc(F)c(F)c(F)c3)c(Cl)cc2Cl)CC1 +O=C(O)CC(NC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1)c1cccc(OCCOCCOCCF)c1 +COCCCCCCCOc1c(OC)cc(CC2CN=C(N)N=C2N)cc1OC +CSc1ccc2c(c1)c1c(n2S(=O)(=O)c2ccccc2)CCC(N(C)C)C1 +CCCCOc1c(OC)cc(C(=O)NCC(C)(C)N(C)C)cc1OC +COc1cc(-c2ccc(NC(C)c3cccc(F)c3)nn2)ccc1-n1cnc(C)c1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(C)(=O)=O)cc2F)n(-c2cc3ccccc3cc2F)n1 +COc1cccc(NC(=O)c2ccc(N3CCCC3)c([N+](=O)[O-])c2)c1 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC2(CC(=O)c3ccccc3O2)C1 +CC(COc1ccc(C2=NNC(=O)C3CC23)cc1)CN1CCCC1C +O=S(=O)(c1cccc(F)c1)c1cn(C2CCNC2)c2cc(F)ccc12 +Cc1c(C)c2c(c(C)c1O)CCC(C)(CCCC(C)CCCC(C)CCCC(C)C)O2 +Cn1c(=O)c2c(nc3n2CCCN3C2CCCCC2)n(C)c1=O +CCc1ccc(-c2cc(Br)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 +CC(C)N1CCN(C(=O)c2ccc(NC(=O)Nc3ccc(C(F)(F)F)cc3)cc2)CC1 +CC(=O)C=CC1CCC(CC(=O)OCc2ccccc2)OO1 +NCC1CCN(c2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)C(=O)C1 +C[n+]1cn(C2OC(COP(=O)(S)OP(=O)(O)OP(=O)([O-])O)C(O)C2O)c2nc(N)[nH]c(=O)c21 +CN(C1CCc2c(CC(=O)O)c3c(F)cccc3n2C1)S(=O)(=O)c1ccc(F)cc1 +CC(=O)Nc1cc(F)ccc1CN1Cc2c(c(O)c3ncccc3c2N(C)S(C)(=O)=O)C1=O +Cc1ccc(S(=O)(=O)N2CCN(Cc3cc([N+](=O)[O-])c4cccnc4c3O)CC2)cc1 +CC(Nc1cc(F)cc(F)c1)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3C)oc12 +CN1OC2(N=C1N)c1cc(-c3cccc(C#N)c3)ccc1CC21CCc2ccccc2C1 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+O=c1[nH]ccc2c(Cc3nnc4ccc(-c5ccccc5Cl)nn34)cccc12 +c1ccc(CC2CCN(CCCCn3nnnc3C(c3ccccc3)c3ccccc3)CC2)cc1 +[C-]#[N+]C1CC([N+]2(C)CCC2)CCC1n1cc(C(N)=O)c(Nc2ccc(C(F)(F)F)cc2)n1 +COc1cc(O)c(C(=O)C=Cc2ccc(N3CCCC3)cc2)cc1OC +OCc1cccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)c1 +Cc1ccc2nc(C)c(CCN3CCc4oc5ccccc5c4C3)c(=O)n2c1 +Cc1cccc(S(=O)(=O)c2ccc3[nH]nc(C4CCN(C)CC4)c3c2)c1 +O=C(O)Cc1sc(C=C2NC(=O)CS2)nc1-c1ccc(Br)cn1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc4ccccc4n3)c2)c2cncnc21 +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(CC(=O)O)cc1 +NC(=O)c1nc(Nc2cccc3cccnc23)sc1NC(=O)c1ccc(Cn2ccnc2)cc1 +O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCN(C(=O)N2CCOCC2)CC1 +CN(CCS(C)(=O)=O)C1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CC1 +Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccn2c(C(C)(C)N(C)C)nnc2c1 +Cc1ccc(-c2cc3ncn(C4CCN(C(=O)N(C)C5CCN(C)C5)C4)c(=O)c3s2)cc1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(c3ccccc3)C2)ncc1Br +CC1(CC(=O)NCc2ccccc2N2CCCCC2)CC2(CCCCC2)OO1 +CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(C)(C)C)CC3)n(C)c2n1 +N#Cc1cnc(C(=O)Nc2ccc(F)c(C3(C(F)F)N=C(N)OC4CC43)c2)c(F)c1 +CCCCCNC(c1c(C(=O)O)[nH]c2cc(Cl)ccc12)c1nnnn1-c1ccc(F)c(Cl)c1 +CC(C)=CCc1c(O)c(CC=C(C)C)c2oc3c(O)ccc(O)c3c(=O)c2c1O +NC(=O)C1Cc2ccccc2CN1C(=O)CCCCCN1CCN(c2ccc(F)cc2)CC1 +CN(C)c1ccc(C=Cc2sc3ccccc3[n+]2C)cc1 +CS(=O)(=O)N1CCc2c(c(-c3ccc(C(F)(F)F)c(SCCN4CCCCC4)c3)nn2CCCN2CCOCC2)C1 +O=C(O)c1c[nH]c2cc(F)c(-c3ccc(OCCC4CCCO4)cc3)c(F)c12 +CC(C)(C(=O)Nc1ccc(N2CCN(C(=O)c3ncccc3C(F)(F)F)CC2)c(Cl)c1)c1ccccc1 +COc1cn(-c2ccccc2)nc1C(=O)NC(CC(=O)O)c1ccccc1C +NC(=O)n1cc(NC(=O)N2CCSC2C(=O)NCc2cccc(F)c2F)c2ccccc21 +COc1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)nc2ccccc12 +CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)CCCc1ccccc1)c1ccccc1)C(C)C +Nc1ccc2c(c1)Cc1c-2nc(O)c2nc(C(=O)O)cn12 +CC(CCC(=O)O)=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +COc1cccc(NCCC2(c3cccc(F)c3)CCOC(C)(C)C2)c1 +O=C(c1ncc(I)o1)C1COc2cc(Oc3ccccc3)ccc2C1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3cccc(C(N)=O)c3)nc2n1 +O=C(Nc1ncc(Br)s1)C1C(C(=O)NC2CCNCC2)C2C=CC1C21CC1 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+CC(C)(C)c1ccc(C(=O)NC2CCC(CCN3CCN(c4nccc5c4CCO5)CC3)CC2)cc1 +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccc(F)c(F)c3)sc12 +COc1cc(OC2CCNCC2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +CC(=CC(=O)NC(C(=O)N1CCCC1C=CCCc1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 +CC(C)(C)c1cc(NC(=O)C2CCCCN2C(=O)N2CC[S+]([O-])CC2)no1 +NC(=O)C1CCCN1C(=O)CCCCCN1CCN(c2ccccc2Cl)CC1 +COc1cc(C=CC=CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O +O=C(OC1C[N+]2(Cc3csc(-c4ccccc4)n3)CCC1CC2)C1(C2=CC=CC2)CCCCCC1 +COC(CN1CCC2(CC1)CC(=O)N(C1=CC(=O)OC1)C2)c1ccc2c(c1C)COC2=O +CC(C)(Nc1ccc(Cl)c(C(=O)NCC(N)=O)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 +COCCc1ccc(OCC(O)CNC(C)(C)CSc2ccccc2C)cc1 +O=C(c1cc2ccccc2[nH]1)c1cc2cc(OCCN3CCCCC3)ccc2[nH]1 +O=C(Nc1ccccc1)N(Cc1ccc(Br)cc1O)c1cc(-c2ccccc2)[nH]n1 +CCc1cc(-c2ccc(C(N)=O)c(N)c2)c2cccc(-c3cnc4ccccc4c3)c2n1 +CC(C)(N)c1ccc(N2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)nc1 +O=C(c1ccc(-c2ccc(=O)n(-c3ccc(F)cc3)n2)cc1)N1CCCC1CN1CCCC1 +CN1CCN(CCNC(=O)c2c(C(N)=O)nc3n2CCOc2cc(F)c(C#CC(C)(C)O)cc2-3)CC1 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+COc1cccc2c1CCN(Cc1ccc(C(C)NC(=O)c3cn[nH]c3)cc1)C2 +CN1CC2CN(c3nc4ccccc4n(C4CCN(C5CCCCCCC5)CC4)c3=O)CC2C1 +O=C(CCc1ccccc1)NC1CCC(c2ccc(O)cc2)CC1 +COc1cc(-c2cccc(C)c2OC)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +Cc1cc(Cl)cnc1C(=O)Nc1cccc(C2(C(F)F)COCC(N)=N2)c1 +COc1cccc2c1nnc1c(C)nc(-c3ccccc3C)n12 +O=C(Nc1cccc(Nc2cc3c(=O)[nH][nH]c(=O)c3cc2Cl)c1)c1cccc(I)c1 +C=CNC(=O)NCCOc1cc2ncnc(Nc3ccc(Br)cc3F)c2cc1NC(=O)C=C +Cc1cc(OC(CCCCNCc2ccc(Cl)cc2)C(=O)NO)ccc1F +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccccc3N)cc21 +CS(=O)(=O)Nc1cccc(-c2n[nH]c(C3CCCCN3C(=O)COc3ccccc3)n2)c1 +Cc1c(C)c2c(c(C)c1O)CCC(C)(c1cc(C3CCCC3)on1)O2 +CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)c2ccc(C(=O)OC)cc21 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2ccccc2cn1 +Cc1ccc(C2CCC(N3CC(NC(=O)CNc4n[nH]c5ccc(C(F)(F)F)cc45)C3)CC2)cn1 +CN(C)C1(c2ccccc2)CCC2(CC1)OCCc1c2[nH]c2ccccc12 +NCCCCCOCC1OC(OCCc2c[nH]c3ccccc23)C(OCc2ccccc2)C(OCc2ccccc2)C1OCc1cccnc1 +O=C(NCc1ccc(S(=O)(=O)c2cc(F)cc(F)c2)cn1)N1Cc2ccncc2C1 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+O=C(Nc1cc(Cl)ccc1-c1ccccc1)NC1(C(=O)O)CCCC1 +COc1cc2c(C)[nH]c(=O)c(Cc3ccc4ccccc4n3)c2cc1OC +COc1cccc2c1ccc1nc3cccc(C(=O)NC(C)CN(C)C)c3nc12 +CCCc1cc2c(C(F)(F)F)noc2c(CCC)c1OC(C)(C)C(=O)O +O=C(c1cc(-c2ccc(Cl)cc2Cl)n[nH]1)N1CCN(CCO)CC1 +c1cc(Nc2nccc(-c3ccco3)n2)cc(OCCn2ccnc2)c1 +Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1 +Cc1c(NS(=O)(=O)c2ccc(CCCCC3CCN(C)CC3)cc2)c(Cc2ccccc2)nn1C +O=c1ccc2c(OCCCCCOc3ccc4ccccc4c3)c3ccoc3cc2o1 +CCC(CC)NC(CC(=O)O)C(=O)N1CCCCC1CCOC1CCN(C(=N)N)CC1 +Cc1cc(Cl)cnc1C(=O)Nc1ccc(F)c(C2(C)N=C(N)OCC2(F)F)c1 +NS(=O)(=O)c1cc2cc(C(=O)NCCN3CCSCC3)sc2s1 +Cc1cc(C)c2nc(NNC(=O)c3ccc(S(=O)(=O)N4CCc5ccccc5C4)cc3)sc2c1 +Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(CN2CCC3(CCCN3)CC2)cc1 +CCN(C1CCN(C(C)c2ccccc2)C1)S(=O)(=O)NCCc1c(-c2cccs2)n[nH]c1-c1cnccn1 +CCCCCCCCCCCCCC(=O)Nc1ccc(C(Br)P(=O)(O)O)cc1 +Cc1ccc(-c2cc3c(-c4cccc(N5CCNCC5)n4)n[nH]c3cn2)cn1 +CCN(CC)C(=O)C1CCC2C3CCC4N(C)C(=NO)CCC4(C)C3CCC12C +OCCCCCOc1cc(Cl)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 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+O=C(O)COc1cnc(C(=O)CNC(=O)c2cc3c(s2)CCNC3)cc1OCC(=O)O +O=C(NCC(=O)N1CCCCCC1)Nc1ccc2cnccc2c1 +CN(C)C1CC23CCC4(O2)C(=CCC2(C)C(c5ccc6ccncc6c5)CCC42)C=C3C(O)C1O +CCOC(=O)C=CC1CCC(CC(=O)OCc2ccccc2)OO1 +Cc1nc2ccccc2n1CCOC(=O)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 +CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1ccnn1C +COc1cc(C2NNCc3nc4ccccc4n32)cc(OC)c1OC +COc1ccc(-c2c(CO)c(CO)cc3cc(OC)c(OC)cc23)cc1OC +CN(C)CCn1cc(S(=O)(=O)c2cccc3ccccc23)c2cccnc21 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC2(CCNC2)CC1 +CCOCCOc1ccc(Cl)c(C(=O)Nc2cc(C(=O)Nc3cccc(Cl)c3C)c3nc(COC)[nH]c3c2)c1 +CCNC(=O)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1 +COc1c2n(cc(C(=O)NCc3ccc(F)c(Cl)c3F)c1=O)C1CCCC13OCCN3C2=O +NCCCCN(Cc1cc2ccccc2cn1)C1CCCc2cccnc21 +CC(C)n1cnc2c(NCc3cc(Cl)ccc3O)nc(NC(C)C(C)(C)O)nc21 +O=C(Nc1ccc(-c2nnc(NCCCN3CCC(F)CC3)o2)cc1)c1ccccc1F +O=C(Cn1c(-c2cscn2)nc2ccccc21)Nc1ccc(Br)cc1 +CC1CCC(C(C)C)C(OC2OC(=O)C(Br)=C2Sc2nnc(-c3ccc([N+](=O)[O-])cc3)s2)C1 +O=C(O)CC1CCC(c2ccc(C(=O)Nc3noc(Cc4ccccc4)n3)cc2)CC1 +C(#Cc1ccc(CN2CCCCC2)cc1)CCN1CCCCC1 +COc1cccc(C(=O)CCCCN2CCN(c3ccccc3OC)CC2)c1 +O=C(Cn1nnc(-c2ccncc2)c1-c1ccccc1)Nc1ccc(-c2ccccn2)cc1 +Cn1ncc(NC(=O)c2ccc(F)c(-c3c(F)cc(C(O)(CO)CO)cc3F)n2)c1C1CCC(N)C(F)CO1 +CC(=O)NC(C)(C)CC1(c2ccccc2)CCN(C(C)c2ccc(-c3ccc(=O)n(C)c3)cc2)C(=O)O1 +Cc1c(S(=O)(=O)Nc2ccc3ncc(N4CCNCC4)cc3c2)sc2ccc(Cl)cc12 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(OCC(C)(C)O)ccc3Cl)nnc12 +COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cc1nn(C)c2ccc(NC(=O)OC3CCCC3)cc12 +Nc1ccc(C(NS(=O)(=O)c2cnccc2NC(CO)Cc2ccccc2)C(=O)N2CCC(CCF)CC2)cc1 +Cc1c(N(Cc2ccc(F)c(F)c2)S(=O)(=O)c2cn(C)cn2)sc2ccccc12 +Cc1ccc(C(=O)Nc2cccc(C(C)C)c2)cc1N1CCc2nc(N)ncc2C1 +Cn1ncc2cc(C3CN(C(=O)C4CCC(N)CC4)CC3c3ccc(C#N)cc3)ccc21 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1(C)CCCN(C(=O)OC(C)(C)C)C1)CC2 +CCN(C(C)=O)c1ccc(Cl)c2nc(NC(=O)c3ccc(F)cc3)sc12 +O=C(NCCCOC1CCN(C(=O)c2ccccc2)CC1)N1Cc2ccccc2C1 +C1=C(c2c[nH]c3ccccc23)CC2CCC1N2CCOc1cccc2c1OCCO2 +O=c1c2c(Nc3ccc(I)cc3F)cncc2cnn1CC(O)CO +Cc1cc(C)nc(N2CC3CN(C(=O)c4c(-n5nccn5)ccc5c4OCO5)CC3C2)n1 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+Cc1occc1C(=O)NN=Cc1ccc(-c2ccccc2)cc1 +CCc1ccc2cc(CCn3ncc4c3nc(N)n3nc(-c5ccco5)nc43)ccc2n1 +COc1ccc(CNc2nc(N3CCCC3CO)ncc2C(=O)CCN2CCOCC2)cc1Cl +N#CC1CN(C(=O)OCCN2CCOCC2)CCC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +Nc1[nH]c(N=Nc2nc(-c3ccccc3)cs2)c2ccccc12 +CNC(=O)c1cccc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(C)c5)cc4)csc23)c1 +Cc1cc(CNc2nc(Nc3cc(C4CC4)n[nH]3)cc(N3CCN(C)CC3)n2)on1 +O=C1c2ccc(-c3ccc(OC(F)(F)F)cc3)cc2CCN1CCN1CCCC1 +O=C(NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1)c1ccc(Cl)cc1 +NC1(C(=O)O)CCN(c2nc3ccccc3n(C3CC4CCC(C3)N4C3CCCCCCC3)c2=O)C1 +COCCOC(=O)N1CCC(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)C(C#N)C1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2cccc(-c3ccncc3)c2)C(=O)N2CCC(CCN)CC2)c1 +COc1ccc(C2=NC(=Cc3cccnc3)C(=O)O2)c(Br)c1 +COC1CN(c2ccc(C(=O)NC3(CC(N)=O)COC3)nc2OCC2CC2)C1 +O=C(CN1CC(c2ccccc2)CC1=O)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +Cc1cc(F)ccc1-c1nccnc1OC1CN(c2ccc3ccccc3n2)C1 +CN(C)Cc1ccc(-c2nnc(Nc3cccnc3Oc3ccccc3C(C)(C)C)s2)cc1 +COc1ccc(N(C)C(=O)NC(C)c2ccccc2)cc1OCCCC(C)C +CN1C(=N)NC2(c3cc(-c4cccc(C#N)c4)cs3)CN(c3ccc(F)cc3)CC2C1=O +CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(C(=O)N3CCC(C(C)(C)O)CC3)n(C)c2n1 +O=C(O)CN1C(=O)C(NC(=O)c2cc3ccccc3[nH]2)N=C(c2ccccc2F)c2ccccc21 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2ccc(C(=O)N3CCNC4(CC4)C3)c(Cl)c2)n1 +O=c1[nH]c(-c2ccc(O)cc2)cn2c(=O)n(-c3ccccc3)nc12 +CCC(OC(C)=O)C(CC(C)N(C)C)(c1ccccc1)c1ccccc1 +COc1ccc(-c2cnc(NC(=O)c3ccc(F)cc3)n2C)cc1 +OCC1CCN(c2ccc3ncc(-c4cc5ccccc5o4)n3n2)C1 +CCCCn1cnc(CN2CCN(c3cccc4[nH]c(-c5ccc(C(C)(C)C)cc5)nc34)CC2)c1C +COc1cccc(S(=O)(=O)Nc2cccn(CC(=O)NCc3ccc(C(=N)N)cc3)c2=O)c1 +CN(C)C(=O)c1ccc(CCC(COc2ccc(-c3cccc([N+](=O)[O-])c3)cc2)N2C(=O)CCC2=O)cc1 +CNc1c(Br)cnc2[nH]c(-c3ccnc(N)c3)nc12 +COc1ncc(-c2cnc3ncnc(-c4ccncc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +Cc1c(CNC2CCC(F)C2)nn(C)c1-c1ccc(F)c(F)c1 +CC(C)(C)c1cc(CN2CCc3cc(S(=O)(=O)Nc4ccc(OCCC5CCOCC5)cc4F)ccc3C2)ccn1 +CC(C)(Nc1ccc(Cl)c(OCC(O)CO)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 +Cc1nc(-c2cccc(-c3nc4c(n3C(C)C)C(c3ccc(Cl)cc3)N(c3cc(Cl)ccc3C)C4=O)c2)c[nH]1 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+NC(=O)c1cccc2c(NCc3cccc(NC(=O)N4CCCCC4)c3)ncnc12 +CCNS(=O)(=O)c1ccc(NC(=S)N2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 +CC(C)CC(O)(c1ccc(C#N)c(Cl)c1Cl)C(F)(F)F +Cn1cc(-c2ccc3ncc4[nH]c(=O)n(-c5ccc(C(C)(C)C#N)cc5)c4c3n2)cn1 +Cc1ccc2nc(-n3nc4c(c3O)-c3ccccc3CC4)sc2c1 +Cc1c(N(Cc2ccc(F)c(F)c2)S(=O)(=O)c2ccc(O)cc2)sc2ccccc12 +CC(C)Oc1ccc2c(C#N)cn(-c3ccc(C(=O)O)c(O)c3)c2c1 +Nc1cccc2c1nc(N)c1nn(-c3ccc(O)cc3)c(=O)n12 +O=S(=O)(Nc1cc(-c2ccc3nccc(-c4ccc(CN5CCOCC5)cc4)c3c2)cnc1Cl)c1ccc(F)cc1F +CN1C(=O)c2cc(C=CC(=O)NO)ccc2OC12CCN(Cc1ccccc1)CC2 +CCCc1nc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)c(C)n1-c1ccccc1OC +CN(C)c1ncc(-c2cncn2CCOc2ccc(Cl)cc2)cn1 +CCN1CCOCCN(CC)CCn2cc(c3ccccc32)C2=C(C(=O)NC2=O)c2cn(c3ccccc23)CCOCC1 +NC1CCC(NC2CC2c2ccc(-c3cccnc3)cc2)CC1 +CCCCC(C=NNC(=O)N(C)C)NC(=O)OC(C)(C)C +O=C(NCCN1CCCCC1)c1ccc(OC2CCN(CC3CCCCC3)CC2)c(Cl)c1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1N(C)c1ncnc2cnc(N3CCOCC3)nc12 +CN(Cc1c(-c2ccccc2)c2ccccc2c(=O)n1C)C(=O)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 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+CC#CCOc1ccc(S(=O)(=O)N(C)c2c(C(=O)NO)cnc3snc(C)c23)cc1 +COc1ccc(C2=C(c3ccc(OC)c(OC)c3)C(=O)N(CC(=O)c3ccc(S(C)(=O)=O)cc3)C2=O)cc1OC +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)F)c3)C(=O)N2C(=O)NCCO)cc1 +Cc1ccc(NC(=O)NC(=O)c2ccc(OCc3ccccc3F)cc2)cc1-c1nc2ccccc2[nH]1 +C=CCOc1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 +Clc1cccc(-c2ccc3ncc(-c4ccncc4)n3n2)c1 +NC(CC(=O)N1CCN(Cc2ccc(F)cc2)C(=O)C1)Cc1cc(F)c(F)cc1F +N=C(N)NCCC(N)C(=O)NCCCCCNCCCCCCCNC(=O)C(CC(N)=O)NC(=O)Cc1c[nH]c2ccccc12 +Cc1ccc2c(c1O)-c1cccc3c1C(C2)N(Cc1ccccc1)CC3 +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N(Cc1ccccc1)C1(C(F)(F)F)CC1 +CCN(c1cc(Cl)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CN(C)C1 +COc1ccc(Cl)c(NC(=O)CC23CC4CC(CC(C4)C2)C3)c1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)NC3CCCNC3=O)cc2F)cn1 +O=[N+]([O-])c1cc(NC(=S)OCCc2ccccn2)ccc1Cl +Cc1ccc(Cl)c2c(C3=NC(=S)NC3=O)c(O)[nH]c12 +CCn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1OCCN(C)C)C2=O +Cc1ccc(-n2nc(C3CCN(C4CCC(NS(C)(=O)=O)CC4)CC3)cc2NC(=O)c2cnn3cccnc23)cc1 +CCc1cn(C(C)C2CC2)c(=O)c(Nc2ccc(OC)nc2C(F)(F)F)n1 +CC12CC(Cc3ccccc3)CC(=O)N1C(C(=O)NC(CCCNC(=N)N)C(=O)c1nccs1)CS2 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCCC(NCC2COC2)CC1 +Cc1ccc(-n2cc(CC(=O)O)c3ccc(C)nc32)c(Cn2nncc2C)c1 +O=C(NO)C(CNS(=O)(=O)c1ccc(OCc2ccccc2)cc1)N1CCCC1 +CCC(C)c1ccc(-n2ncc(Cl)c(Oc3ccc(OC)cc3)c2=O)cc1 +Oc1ccc2c(c1)C1CC(c3ccoc3)(c3ccoc3)C2c2cccc[n+]21 +Nc1cc(Cn2c(C(=O)O)c(-c3ccc[nH]c3=O)c3cc(OC(F)(F)F)ccc32)ccn1 +COC1CCN(CCCOc2ccc(-c3cc4c(C(=O)O)c[nH]c4cc3Cl)cc2)CC1 +Cc1cccc(C(O)CNC(=O)C2CCN(C(=O)Cn3c(=O)sc4ccc(Cl)cc43)CC2)n1 +N#CCC(=O)N1CCC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)CC1 +CCC1(O)CC(C)(C)c2cc(-c3ccc(C#N)n3C)ccc21 +CC(NS(=O)(=O)c1ccc(-c2c(C#N)c3ncc(Cl)cc3n2C2CCC2)nc1)C(F)(F)F +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(c3ccccc3F)CC1)CC2 +Nc1c(S(=O)(=O)O)cc(Nc2ccc(Oc3ccccc3)c(S(=O)(=O)O)c2)c2c1C(=O)c1ccccc1C2=O +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NC(C)C(F)(F)F)c12 +O=C(O)c1ccc(-c2ccc(-c3cc4c(F)ccc(F)c4o3)[nH]2)cc1 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+O=C(c1cccc(C(F)(F)F)c1Cl)N1C2CCCC1c1nnc(-c3cscn3)n1C2 +C=Cc1c(OC)cc(O)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12 +Nc1nc(-c2ccco2)c2cnn(Cc3ccccc3[N+](=O)[O-])c2n1 +CC(NC(=O)Nc1cc2[nH]nc(NC3CC3)c2cn1)c1ccccc1 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc(O)c(F)c1 +CC1(C)NCC(c2ccc(Cl)cc2)c2ccc(-c3cnc(C(F)(F)F)cn3)cc21 +Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C[N+]4(C)CCCCC4)cc2)CO3)cc1 +Cn1ncc(C(=O)N2CCC2)c1C(=O)NCCc1nc(-c2ccccc2)nn1-c1ccccc1 +COc1cccc(-c2ccc(O)c(CN3CCC(Cc4ccccc4)CC3)c2)n1 +CC(C)C1=C(C(=O)N2CCNC(=O)C2)SC2=NC(C)(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21 +COc1ncc(-c2cnc3nc(N)nc(C)c3c2)cc1NS(=O)(=O)c1ccccc1 +O=C(CNCc1ccc(Cl)cc1)Nc1cc(CO)cc(Nc2ccnc3cc(Cl)ccc23)c1 +Nc1nc(-c2ccccc2)c2c(n1)-c1cc(Cc3ccncc3F)ccc1C2=O +CC(=O)N1CCC(C(=O)Nc2ccc(COc3ccnc4cc(C(F)(F)F)ccc34)cc2)C(C(=O)NO)C1 +CCc1nc(C)nn1-c1cc(N2CC(c3nc4ccccc4n3C)C2)nc(C)n1 +CC(=O)Nc1cccc(C#Cc2cncnc2Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)n1 +c1ccc(CCN2CCC(c3cc(C4CCCCC4)n[nH]3)CC2)cc1 +CC(C)(NC(=O)c1cncs1)C(=O)Nc1nc(-c2ccc(F)cc2)c(Oc2ccc(F)cc2)s1 +CC1(C)CC(=O)C=C(c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)C1 +O=C1CC2(CCN(c3c(Cl)cncc3-c3ccc(N4CCOCC4)cc3)CC2)CN1 +CC(C)c1ccc(OCC(=O)NNC(=S)NC(=O)C2CC2)cc1 +CC(C)CC(CC(=O)NO)C(=O)NC(Cc1ccccc1)C(=O)NCc1ccccc1 +CC1C(=O)NCC1COc1nc(-c2ccc(C#N)cc2)cc2ncccc12 +CC(c1ccc(Cl)cc1)N1C(=O)c2cc(I)ccc2N(CCCCC(=O)O)C(=O)C1c1ccc(C(F)(F)F)cc1 +Cc1nn(-c2cc(Br)c(Cl)cc2F)c(=O)n1C(F)F +O=C(NCCCCCCNc1c2c(nc3ccccc13)CCCC2)c1cc2c([nH]c3ccccc32)c(-c2ccccc2)n1 +CCCCCCC(C)(C)C1=CC(=O)C2=C(OC(C)(C)c3cn(C)nc32)C1=O +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc([N+](=O)[O-])c2)[nH]c1=O +c1cc2c(cc1OC1CCOCC1)CCC1(CCN(C3CCC3)CC1)O2 +CCCCCCCNC(=O)Oc1cccc(CN(CCC)CCCOc2ccc3c(=O)c4ccccc4oc3c2)c1 +Cc1[nH]c(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)NC2CC3CCC2C3)nc1C(=O)O +NC1(c2ccc(-c3nc4ccc(-c5cccnc5)cn4c3-c3ccccc3)cc2)CCC1 +Cc1cc(OCC2CCN(C(=N)N)CC2)cc(OS(=O)(=O)c2cccc3ccccc23)c1 +Cc1cc2c(OCC(O)CN3CCC(c4cc5cc(Cl)ccc5s4)CC3)cccc2[nH]1 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+Cc1cnc(Cl)nc1-c1ccc(N(Cc2cccc(CN3CCC(F)(F)C3)c2)C(=O)c2ccc(O)cc2O)cc1 +O=C(c1ccc(-c2cccc(C(F)(F)F)c2)cc1)N1CCN(c2ncccn2)CC1 +CCN(C(=O)CO)C1CN(C(=NC#N)Nc2cccc(OC(F)F)c2)N=C1c1ccc(Cl)c(C)c1 +O=S(=O)(c1ccccn1)N(Cc1ccc(F)c(F)c1)c1cc2ccccc2s1 +CCCN(Cc1ccc(OCCn2c(=O)ccn(C)c2=O)c(C)c1)C(CC(=O)O)c1ccc(Cl)cc1 +N#CC1(n2cc(C(NC(=O)c3ccc(F)cc3)C3CCCCC3)nn2)CC1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3cccc(NS(C)(=O)=O)c3)[n+]([O-])c2n1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(CO)c1cccc(F)c1 +Cc1nc(-c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)co1 +CCCCCCCCCCOC(=O)CC(=O)Nc1c(C(C)C)cccc1C(C)C +CC(C)CCC1(C)CN(C2CCCCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O +Cc1cc(OCP2(=O)OCCC(c3cccc(Cl)c3)O2)c2c(c1C)Cc1scnc1-2 +CC(C)=CCN1CCn2c(=S)[nH]c3cccc(c32)C1C +CC(OC(=O)C12CC3CC(CC(C3)C1)C2)c1ccncc1 +O=C(O)c1cc(-c2cccc(-c3ccc4c(c3)CN(C3CCCC3)C4=O)c2)ccc1Cl +CC1=C(c2ccccc2)CCN(C(=O)C2NCC3(CC3)CC2C(=O)NO)C1 +COc1ccc(-c2ccc(C(=O)NCC(C)(C)C)cc2C(=O)O)c(C(=O)Nc2ccc(C(=N)N)cc2)n1 +Cc1cc(C(=O)N(C)C)cc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(Cl)c3)CC2)n1 +CN(CCN1CCCC1)C(=O)Cc1ccccc1[N+](=O)[O-] +CCCc1nc(C(=O)NCC(O)CN2CCN(c3cccc(Cl)c3C)CC2)cn1-c1ccc(Cl)cc1 +O=C(Nc1ccc(C2=CCN(C(=O)c3ccccc3)CC2)cn1)N1Cc2ccccc2C1 +COc1ccc(C(NC(C)CC(N)=O)C2CC2)c(F)c1C(=O)c1cccc(F)c1 +O=C(CNc1n[nH]c2ccc(C(F)(F)F)cc12)NC1CN(C2CCC(O)CC2)C1 +CCS(=O)(=O)N(Cc1ccccc1-c1ccccc1)C1CCNC1 +NC(=O)CNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +O=S(=O)(Nc1ccc2c(CCC3CCN(Cc4ccccc4)CC3)noc2c1)c1ccccc1 +C=CCc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)c(OC)c1 +CCS(=O)(=O)Nc1cccc(-c2cc(C)cc(Nc3nccc(C(F)(F)F)n3)c2)c1 +COCc1c(-c2ccc(C(=N)N)cc2)oc(-c2ccc(C(=N)N)cc2)c1COC +O=C(NOCC(O)CO)c1c(Nc2ccc(I)cc2F)c(F)c(=O)n2c1CCC2 +CC(C)N1CCC(C(CN2CCN(CCCc3ccccc3-c3cccc(F)c3)CC2)c2ccc(F)cc2)CC1 +CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(I)cc32)c1C +CC1CC(C)(C)CCC12OOC1(CCC(C)(C)CC1C)OO2 +Cn1c(SCC(=O)C2(O)CCC3C4CCC5=CC(=O)C=CC5(C)C4C(O)CC32C)nc2ccccc21 +CC(C)COC(=O)c1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl +C=C(c1ccccc1)c1ccc(C2CC3CCC(C2C(=O)OC)N3C)cc1 +O=C(O)Cc1ccccc1S(=O)(=O)c1ccc(-c2ccc(NC(=O)CF)cc2)cc1 +Cc1cc(OCF)cnc1C(=O)Nc1ccc(F)c(C2(C)COC(C)(C(F)(F)F)C(N)=N2)n1 +CC(C)Nc1ncc(-c2ccnc(-c3ccccc3Cl)n2)s1 +N=C(N)NCCCC1CC(C(=O)NCC(NC(=O)OCc2ccccc2)C(=O)O)=NO1 +NS(=O)(=O)c1ccc(N2N=C(C(F)(F)F)CC2c2cccc3ccccc23)cc1 +Clc1ccc(-c2nc(-c3ccc(-c4ccccc4)cc3)c(-c3ccncc3)[nH]2)cc1 +COc1cnc2[nH]cc(Cc3ccc(NCc4ccccc4Cl)nc3F)c2c1 +O=C1NC(C(=O)O)Cn2cc(nn2)CC=CCOc2ccc(Cl)c1c2 +Cc1ncc(-c2ccnc(Nc3ccc(C(=O)NC4CCN(C)CC4)c(F)c3)n2)n1C(C)C +CCN1C(=O)N(c2cccc(C(=O)NC)c2)C(=O)N(c2ccccc2)c2cc(C(F)(F)F)ccc21 +N#Cc1ccc(OCc2ccc3nonc3c2)cc1OC(CCC(=O)O)c1ccccc1 +Cc1cc(CN2CCC(O)CC2)ccc1C(=O)Cn1ncc(OCc2ccc(Br)cn2)cc1=O +CN(C)Cc1cccc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)c1 +O=C(NCc1ccc(OC(F)(F)F)cc1)C1CCCC1C1=NOC(c2ccc(Cl)cc2)C1 +CCN1CC(C)(C)Oc2nc(N3CCOCC3C)nc(-c3ccc(NC(=O)Nc4cnc(N5CCOCC5)cn4)cc3)c2C1=O +CN(CP(=O)(O)O)C(Cc1ccc(-c2ccccc2)cc1)c1nnn[nH]1 +O=c1sc2ccccc2n1CCCCCN1CCN(C2CCCCC2)CC1 +O=C(Oc1ccc[n+]([O-])c1)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +O=C(Oc1ccc2c(c1)CCC2)N(Nc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CC(C)S(=O)(=O)NCC1CCC(NCCN2CCOc3ccc(F)cc32)CC1 +N#Cc1ncccc1CSc1nc(O)c(C#N)c2ccc(F)cc12 +CC(C)CC(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)OC(C)(C)C +CC(C)NC(=O)CCc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1 +CCCOc1cc(C2(c3cccc(-c4cccnc4)c3)N=C(N)N(C)C2=O)ccc1OC +Cc1ccc2c(c1)nc(CCn1c(=O)c(C)nc3cccnc31)n2-c1ccccc1 +Cn1cncc1C(=O)NC1CCCC(Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1 +CC(C)C(NC(=O)c1cc(Cl)ccc1C(F)(F)F)C(=O)c1ccc([N+](=O)[O-])cc1 +COc1ccccc1N1CCN(CCNC(=O)Cc2ccsc2)CC1 +COC1CCC2(CC1)Cc1ccc(Sc3ccccc3)cc1C21NC(N)N(C)C1=O +COc1nc(NCCc2ccc(OCF)cc2)nc(-c2ccc(OC)c(C(C)(C)O)c2)n1 +O=C(O)c1cccc2c3c(n(Cc4ccccc4F)c12)CCCC3 +COc1ccc(C2=NN(CCCCc3ccc(C4=NNC(=O)CC4C)cc3)C(=O)C3CC=CCC23)cc1Cl +CCN(CC(=O)NC(CC(=O)O)C(=O)NC(CCCC1CCCCC1)C(=O)O)C(=O)CCCC1CCNCC1 +C#CCCC(=O)Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)C(C)(C)CO3)cc1 +COC12CCC3(CC1CNC(=O)C(N)CO)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +NCc1cccc(-c2nc(-c3ccc(F)cc3)c(-c3ccnc4[nH]c(-c5ccccc5)cc34)[nH]2)c1 +Cc1ccc(-c2nc3ccc(C)cn3c2NCc2ccccc2)cc1 +O=C(O)c1ccc(CN(Cc2cccc(F)c2)S(=O)(=O)c2ccccc2)cc1 +Cc1cc(C(=O)Nc2cccc3c2CCCC3)nn1-c1cccc(C(F)(F)F)c1 +O=C(Oc1ccc(Oc2ccc(C(F)(F)F)cn2)cc1)N1CCC(O)CC1 +CN1CC2CCN(c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3)C2C1 +Cc1ccc2c(c1)c1c(n2CCc2cccnc2)CCN(C)C1 +Cc1cc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c(C)c(C)n1 +Cc1c(Nc2c(C#N)cncc2C=CCCN2CCN(S(C)(=O)=O)CC2)ccc2[nH]ccc12 +CC(=NNC(=O)COc1cccc2cccnc12)c1cccs1 +COc1cc(OC)cc(C(=C(C)C)c2ccc(OC)c(O)c2)c1 +CC1(C)COCCN1c1nnc(-c2ccc3[nH]cc(-c4cncc(C5CC5)n4)c3c2)o1 +COC(=O)Nc1ccc2c(c1)NC(=O)CCCCC(NC(=O)C=Cc1cc(Cl)ccc1-n1ccnn1)c1nc-2c[nH]1 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(Cc2ccc(C(F)(F)F)cc2)C(=O)CO)c1 +Cc1cc(C)cc(S(=O)(=O)N2CCc3ccc(C(=O)Nc4nc(CC(=O)O)cs4)cc32)c1 +CN(C)CCC(CNC(=O)Nc1ccc(F)cc1)c1ccc(-c2cccc(C#N)c2)cc1 +CC(C)C(C)(c1ccc(-c2cnc(N)nc2)nc1)c1noc(-c2cnn(CC#N)c2)n1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(-n2cc(Cl)c3cc(-c4ccc(F)cc4F)cnc32)cc1F +CC(C)CC(NC(=O)C1OC1C(=O)O)C(=O)Nc1c(F)cccc1F +CC(C)(CO)Nc1ccc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)nn1 +O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(c2cnc3n2CCCC3)CC1 +O=C(NC1CCCC1COc1ccccc1)C1CCN(c2nc3cc(Cl)ccc3o2)CC1 +COc1cccc2c1NC(=O)C(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)N=C2c1cccc(C)c1 +O=C(c1ccccn1)N(Cc1cccs1)C1(C(=O)NC2CCCCC2)CCCCC1 +CN(C)CCOc1ccc2c(c1)CCn1nc(-c3ccc(NC(=O)Nc4c(Cl)cccc4Cl)cc3)c(C(N)=O)c1N2 +O=C(Nc1ccc(OC2CN(C(=O)C3CCCC3)C2)cc1)N1Cc2ccncc2C1 +O=S(=O)(Nc1cccnn1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1C1=CCNCC1 +CC(C)c1ccc(C(=CCCCCC(=O)O)c2cccnc2)cc1 +CN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(F)cc2)n(C)c2ccccc12 +CC1(C)CC(NC(=O)Nc2ccc3c(c2)NC(=O)C(N2CCCOCC2)C3)c2ccc(F)cc2O1 +COc1ccc(-c2ccc3c(c2)NC(=O)C3=Cc2[nH]c(C)c(CCC(=O)O)c2C)cc1 +O=C(C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2)Nc1ncccc1F +Cc1nc(-c2nc(C(=O)NC(C(=O)OCC=CCCS)C(C)C)cs2)cs1 +Cn1c(=O)c2c(nc(N3CCCC(N)C3)n2Cc2ccccc2Cl)c2ccc(-c3ccccc3)cc21 +COc1ccccc1N1CCN(CCCC(=O)Nc2ccn3nccc3c2)CC1 +Fc1ccccc1CNc1ncnc2c1cnn2CC(Cl)c1ccccc1 +CC1C(=O)NCC1C(=O)Nc1cc(-c2cccc(OC(F)(F)F)c2)n(CC2CCOCC2)n1 +O=c1c2cc(Br)ccc2n2nnc3ccc(NCCCO)c1c32 +CC(C)CN(Cc1ccc(-c2ccc(NS(C)(=O)=O)cc2)cc1)S(=O)(=O)Cc1ccccc1 +Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCN(C)c3cccc(C)c32)cc1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)n[nH]2)cc1Nc1ncnc2cnc(NCc3ccccc3)nc12 +CC(C)c1c2cc(-c3ccnc(NC4CCC(NC5CCOCC5)CC4)n3)ccc2nn1C +OC(c1ccc(Cl)cc1)(c1cccnc1)c1cnc(OCC2CC2)nc1 +CC(C)=CCCC(C)=CCCC(=CCOP(=O)(O)OP(=O)(O)O)C(C)(C)C +COCCNc1ncc2c(F)cc(C(=O)NC(c3ccc(OC)c(F)c3)c3cnn(C)c3)cc2n1 +CN1CC2CC1CN2c1ccc(-c2ccc3sccc3c2)cn1 +NC1CCN(Cc2ccn3ncnc(Nc4ccc(OCc5cccnc5)c(Cl)c4)c23)CC1 +CN(C)CCc1c[nH]c2ccc(Cc3nc(-c4ccc(NS(C)(=O)=O)cc4)no3)cc12 +CCNC(=O)C(c1ccccc1)C1CCN(c2ccc(NC(=O)Nc3c(C)cccc3C)cc2F)CC1 +O=C(Nc1ccc2nc(CO)cn2c1)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 +COc1ccc(-n2cnc3cc(NCc4cccc(OC)c4OC)ccc32)cc1 +CCCc1ccc(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(CC)c3)no2)cn1 +CSCCC(NC(=O)Cc1ccccc1)C(=O)SCC(=O)O +O=C(O)c1ccc(-c2ccc(Cl)cc2)c(COc2ccc(-c3nc4cc(C(=O)O)ccc4n3C3CCCCC3)cc2)c1 +O=C1OCCN1c1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(C(O)C(F)F)cc2)c1 +CCCCCn1cc(C(=O)NC2C3(C)CCC(C3)C2(C)C)c(=O)c2cc(Br)ccc21 +CSCCC(NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CN1C(=NC(=O)OC(C)(C)C)NC(C)(c2cc(-c3cccc(-c4ncco4)c3)ccc2F)CS1(=O)=O +Oc1cc(-c2cccc(Cl)c2)nc2cc3c(cc12)OCO3 +CC(C)(C)c1cc(C(=O)Cn2c(=N)n(Cc3ccccc3)c3ccccc32)cc(C(C)(C)C)c1O +CC(C)c1cccc(C(C)C)c1OC(=O)NCC(NC(=O)OC(C)(C)C)c1ccccc1 +COCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccccc2)c1 +OCCN(CCO)CC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1 +Cc1ccc(N(C(=O)NCC2CCC(COCC(=O)O)CC2)c2ccccc2)cc1 +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)NN(C)C)c1 +CC1(CCC2CCCCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21 +CC1CCCN1c1cccc(Nc2cc(-c3ccc(OCCN4CCCCC4)cc3)nn3ccnc23)n1 +NC(=O)c1cccc2c1C(=O)N(c1cccc(C3CCNCC3)c1)C2 +Cc1ccc(NC(=O)C2CCCO2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +C=CC(O)C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +CC(NC(=O)C(C)(C)Oc1cc(F)cc(F)c1)C(Cc1ccc(Cl)cc1)c1ccccc1 +CCCCCCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +CC1(O)C(O)C(CCl)OC1n1cnc2c(NC3CC4CCC3C4)nc(Cl)nc21 +COC1CC(NC(=O)C2CCCC2c2cc(-c3ccccc3)on2)(c2ccccc2)C1 +Cc1ncoc1-c1nnc(SCCCN2CCC3(CCCc4cc(Br)ccc43)C2)n1C +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCC(C)c1ccccc1)CC2 +FC(F)(F)c1cc(N2CCOCC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2c(C)ccc3ccccc23)c(Cl)c1 +O=c1ccc(-c2ccc(OCCCN3CCCC3)cc2)n[nH]1 +O=C(NC1CCN(Cc2ccccc2)CC1)C(O)(c1ccccc1)C1CCC(F)(F)C1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1cc(C(F)(F)F)nn1Cc1ccccc1 +O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(OCC2(C(F)(F)F)CCCC2)cc1F +CS(=O)(=O)c1ccc(-n2cc(C(F)(F)F)nc2-c2ccc(Cl)cc2)cc1 +O=C(NC(CO)c1ccc(F)cc1)c1cc(-c2[nH]ncc2-c2cccc(Cl)c2)c[nH]1 +CC1=C(c2nc(-c3ccc(C#N)cc3)cs2)C(c2ccc(F)nc2)NC(=O)N1 +Fc1cccc(-c2cc(Cl)ccc2Cl)c1-c1nc(C2CCNCC2)no1 +Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c1[nH]c1ccc(O)cc12 +COc1ccc2nc3c4c(nccc4c2c1)-c1ncccc1C3=O +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(=O)cc(N2CCOCC2)[nH]1 +COc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)oc3ccccc23)cc1Cl +NS(=O)(=O)c1ccc(CCNC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +CCN1c2ncc(CCOc3ccc4c(C(=O)O)cccc4c3)cc2C(=O)N(C)c2cccnc21 +CCC1CN(c2ncc(-c3nnc[nH]3)nc2C)C(C)CN1C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1ccc(Cn2nc(C(=O)NC3CC4CCC3(C)C4(C)C)c(C)c2-c2ccc(Cl)c(C)c2)cc1 +Nc1nc2c(N)[n+]3cnc2n1C1CC(O)C(COP(=O)(O)OP(=O)([O-])OCC2OC3C(O)C2O)O1 +COc1cc2c(N)nc(N3CCN(C(=O)CC4CCCN4)CC3c3ccccc3)nc2c(F)c1OC +CC1(C)CC(=O)c2c3c(n(-c4ccc(C(N)=O)c(NC5CCOC5)c4)c2C1)CCCC3 +Cn1nccc1CC(=O)NCc1cccc(C(F)(F)F)c1Cl +CC(C)Cn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)NC3=O +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(N3CCOC3=O)cc12)C(=O)O +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(N)CC2 +COC1C(c2ccc(C#N)c(Cl)c2C)=NN2CC(O)CC12 +CN1C2CCC1CC(CCOC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +Cc1ccc(C2=NN(c3nc(-c4ccc(Cl)cc4)cs3)C(c3ccc([N+](=O)[O-])cc3)C2)cc1C +O=C(Cn1c(=O)ccn(CCCCCOc2ccc(Br)cc2)c1=O)Nc1ccc(Cc2ccccc2)cc1 +O=C(NCc1ccc(F)c(F)c1)c1c(C2CCCC2)n(Cc2ccccc2)c2ccc(O)cc12 +CCN(c1ccc2nc(O)cc(C(F)(F)F)c2c1)C(C)C +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(C)cn3)CC2)CC1c1ccc(Cl)c(F)c1 +Cc1nc2c([N+](=O)[O-])c(Cl)c(Cl)cc2n1Cc1ccc(O)cc1 +Cc1ccc(C(=O)Nc2cccc(C(C)(C)C)c2)cc1-c1ccc(C(=O)NCC2CC2)cc1 +O=C(C1CCc2c(Cl)cc(OCc3ccc(C(F)(F)F)cc3)c(=O)n21)N1CCCC1 +CCN1C(=O)CNc2ncc(-c3ccc(-c4nc[nH]n4)nc3C)nc21 +O=S(=O)(Nc1nccnc1-c1ccc(Cn2c(-c3ccccn3)cc3ccccc32)cc1)c1ccccc1C(F)(F)F +CCOc1cc(Cl)ccc1-c1onc(C(=O)NC2CCOCC2)c1C +Cc1cc(NC(=O)c2ccccc2CO)nn1Cc1cc(Cl)ccc1OCC(C)C +O=C(NO)C1CC2(CC2)CNC1C(=O)N1CCC(c2ccccc2)C1 +COc1ccc(-c2c[n+](CC(=O)c3ccc(C)cc3)c3n2CCC3)cc1 +Nc1nc(NCCCCC2CCCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CCCCc1ccc(-c2n[nH]c3cnc(-c4cccnc4)cc23)nc1N1CCCC(N)C1 +O=C(N1CCC(c2c[nH]c3ncccc23)C1)C1(Oc2ccc(F)cc2)CC1 +O=C(Oc1cccc2c1C(=O)C=C(N1CC1)C2=O)c1ccc(F)cc1 +CCNC(=O)C1OC(n2cnc3c(NC45CC6CC(CC(C6)C4)C5)ncnc32)C(O)C1O +NC(=O)c1ccc2[nH]c(-c3ccc(C(O)c4ccc5c(c4)OCCO5)cc3)nc2c1 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+COc1ccc(Nc2ccc3c(c2)C(=O)N(C)C3=O)cc1 +CN(C(=O)C1C(c2ccccc2)=C1c1cccc(Cl)c1)C1CCCCC1N1CCCC1 +COc1cc(CC(C(=O)c2cc(OC)c(OC)c(OC)c2)=C(C(=O)O)c2ccc3nsnc3c2)cc(OC)c1OC +Cc1ccc(S(=O)(=O)NC(=N)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)cc1 +Fc1cc(F)c(-c2c(Cl)nc(-c3ccco3)nc2NCC(F)(F)F)c(F)c1 +CC(C)c1ccc(S(C)(=O)=O)cc1C#Cc1cc(C#N)ccc1OCC(=O)O +OC1C(O)C(n2cnc3c(NCc4cccc(Cl)c4)nc(C#Cc4ccccc4)nc32)C2CC12 +Cc1nc(NCc2nnc(C3CC3)s2)cc(OCC2CC2c2ccccn2)n1 +COc1cc(C2(C)CCCc3nc(SCc4ncccn4)n(-c4ccc(F)cc4)c32)ccc1Cl +N#CC1CC(F)CN1C(=O)C1CC(CC(=O)N2Cc3ccccc3C2)C(=O)N1 +CC(C)CCN1CCN(c2ccnc(-n3ccnc3)n2)C(CC(=O)NCc2ccc3c(c2)OCO3)C1 +COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1ccc(C(N)=O)cc1C)C2=O +Cc1ncc2c(-c3ncc4c(n3)NC(=O)C4(C)C)nn(Cc3ccccc3F)c2n1 +O=C(c1nn(-c2cccc(CN3CCC(O)CC3)c2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +O=C(NCCCCCCNC(=O)N1Cc2ccccc2C1)N1Cc2ccccc2C1 +O=C(NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCCN2CCC2)N1)c1ccc2ccccc2c1 +C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc(C(=O)NC(C(=O)O)C(C)C)cc1 +C=CC(=O)Nc1cccc(Cl)c1Nc1ncc(OCc2cc(OC)cc(OC)c2Cl)cn1 +CCC(c1cc(O)nc(SC(C)C)n1)c1cccc2ccccc12 +CC1c2c([nH]c3ccc(C(F)(F)F)cc23)CC2CCN(CCCC3(C(=O)O)CCOCC3)CC21 +CC(=O)OCCCCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)nc(O)c21 +Nc1ncnc2c1nc1n2C2OC(COS(=O)(=O)NC(=O)C(N)CCC1)C(O)C2O +COc1ccc(Nc2ncc(-c3ccccn3)cc2-c2nc(C)nc(N)n2)cn1 +CC(C(=O)Nc1cc(C2CC2)[nH]n1)c1ccc(N2Cc3ccccc3C2=O)cc1 +FC(F)(F)Oc1cccc(-n2cc(-c3ccccc3NCc3ccncc3)nn2)c1 +CC(CC1=NC2C(C=NN2c2ccccc2Cl)C(=O)N1)C(F)(F)F +CCN(CCCCCCOc1cccc(-c2cc(=O)c3c(O)c(OC)c(OC)cc3o2)c1)Cc1ccccc1OC +CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCCC3COC)cc(Br)c21 +Cc1nc2cc(-n3ncc(C(=O)c4cc5ccc(Cl)cc5[nH]4)c3N)ccc2[nH]1 +CC(C)CNC(=O)c1ccc(-c2ccc(-c3ccsc3)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +CCCN1CCC(NC(=O)c2nc3c(C(N)=O)cccc3[nH]2)CC1 +CCC#CCOc1cc(CNc2ccc(C(F)(F)F)cc2)ccc1Sc1ccc(OCC(=O)O)c2c1CCCC2 +Cc1cc(OCC2COc3ccccc3O2)cc(C)c1C(=O)Nc1cc(CC(=O)O)ccc1Cl +O=C(NN=Cc1ccc(O)c(O)c1O)c1ccc(O)cc1 +O=C(O)c1cccc(C(=O)C=Cc2ccc(OCc3ccc4ccccc4n3)cc2)c1O +COc1ccc(CNC(=O)c2cccc3c(-c4cccnc4)coc23)cc1OC +COc1ccc2nc3cc(Cl)ccc3c(Nc3cc(CN4CCCC4)c(O)c(CN4CCCC4)c3)c2n1 +CC(=O)Nc1nc(Cc2nnc(SCC(=O)NNC(=O)CCl)n2NC(=O)c2ccc(Cl)cc2)cs1 +Cc1cccc(NC(=O)NC2N=C(c3ccccn3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)c1 +COc1ccc(S(=O)(=O)N(CC(O)C(Cc2ccccc2)NC(=O)OC(C)(C)C)OC2CCCC2)cc1 +Cc1cc(C2CCC2)c(-c2ncc(C#N)[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +COc1cc(CN2CCN(c3ccc(Cl)cc3)CC2)ccc1OCCF +OCC1OC(n2cnc3c(NN4CCCCC4)nc(F)nc32)C(O)C1O +Cn1cccc1-c1n[nH]c2cnc(-c3cncc(OCC(N)Cc4ccccc4)c3)cc12 +COc1cc(NC(=O)c2cccc(NC(=N)N)c2)ccc1CC(NC(=O)OC(C)C)C(=O)O +CC(=O)NCC(NC(=O)c1ccc(-c2nc(C3CCC(O)CC3)cnc2N)cc1F)c1cccc(Cl)c1 +CC(=O)c1ccc2[nH]cc(C3=CCCN(C)C3)c2c1 +NC(=O)c1cncc(Oc2ccc3c(NC(=O)c4cccc([N+](=O)[O-])c4)cccc3c2)c1 +Cc1ccc(Oc2ccc3c(c2)S(=O)(=O)NCN3C)cc1 +CN1CC2C(CCC3(C)C(C(=O)NC(c4ccccc4)c4ccccc4)CCC23)C2(C)CCC(=O)C=C12 +CCS(=O)(=O)c1ccc(OC)c(-c2ccc(C(C)N3CCCCC3)[nH]2)c1 +CC1CN(c2ncnc3[nH]cc(-c4cccc(F)c4)c23)CCO1 +COc1cccc(Cc2ccc3sc(-c4ccnc(N)n4)c(C)c3c2)c1 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+COc1ccc2c3c1OC1C4(OC)CCC5(CC4CNCC(N)=O)C(C2)N(CC2CC2)CCC315 +Nc1ccn(C2CC(O)C(COP(=O)(O)CP(=O)(O)OP(=O)(O)O)O2)c(=O)n1 +CN(C(=O)c1ncccc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1)C1CCOCC1 +Fc1ccc(-c2cnn3c(-c4cccs4)ccnc23)cc1 +O=C(Nc1ccc(O)cc1)N1CCN(c2ccccc2)CC1 +O=C(O)CC(Cc1nc(CCCc2ccc3c(n2)NCCC3)no1)c1cnc(C2CC2)s1 +Cc1nc(NCc2ccc(C(F)(F)F)cc2)nc(-n2ccnc2C)c1[N+](=O)[O-] +COc1cc(C2C(C#N)=C(N)Oc3cc(N(C)C)ccc32)cc(Cl)c1OC +N=C(N)c1cc2cc(-c3cccc(OCc4cccc(F)c4)c3)ccc2s1 +COCC1CNC(C)CN1CC(=O)N1CC(C)(C)c2cc(=O)n(Cc3ccccc3)cc21 +CCCCCCCCCCCC(O)CC(=O)NC(CC(N)=O)C(=O)NC(C(=O)NC(C=O)CC(C)C)C(O)CC(N)=O +COCCCN(C)c1ncnc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c1F +COC(=O)c1cn(-c2ccc3c(c2)C=CS(=O)(=O)O3)nn1 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCC(O)CC4)cc3)cc12 +N#CC(O)C(CC1CCCNC1=O)NC(=O)C(Cc1ccccc1)NC(=O)C=Cc1ccccc1 +OC1COC(n2cc(-c3ccccc3)c3c(Nc4ccc(F)cc4)ncnc32)C1O +CC(N)(CCc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O +Cc1ccoc1-c1c2c(nn1C)CCc1cnc(Nc3ccccc3)nc1-2 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+COc1cc2c(cc1OC)C(=O)C(=Cc1ccc(CN(C)C)cc1)C2 +CCCOc1[nH]cc2nc3ccc(OCc4ccccc4)cc3c-2c1COC +O=S(=O)(c1cccc2ccccc12)c1n[nH]c2ccc(NCC3CCNCC3)cc12 +CC(C)Oc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +CC(C)(C)C(O)C(=O)N1CC2CC2C1C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +Cn1cc(-c2ccc(-c3cnc(N)c4ccc(C(=O)N5CC(F)(F)C5)nc34)cc2)cn1 +CNC(C)C(=O)NC1CCc2ccccc2N(Cc2c(C)ccc3ccccc23)C1=O +Cc1c(C(O)CN2CCCC3(CCN(CC(O)c4ccc5c(c4C)COC5=O)C3)C2)ccc2c1COC2=O +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1cccnc1O +COc1cc(C(O)CN2CCN(CCc3ccc4c(c3)COC4=O)CC2)c(F)cc1C#N +N#Cc1ccnc(Nc2cc(C3CCN(C4COC4)C3)n(C3CCCC3)n2)c1 +Cc1cncc(-n2nnc3c2CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)C3C)n1 +COC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5 +CCCN(CC)Cc1ccc(CCn2ccc(OCc3ccc(F)cc3)cc2=O)cc1 +O=C(CCC(NC(=O)OCc1ccccc1)C(=O)OCc1ccccc1)NNc1ccc(OCc2ccccc2)cc1 +COC1COCC1NC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1 +CCOc1ccccc1CNc1nc(Cl)nc2c1ncn2C1C(O)C(O)C2CC21 +CCc1cccc(N(C)C(=N)N(C)c2cc(Br)ccc2Br)c1 +Cc1nc2ccc(-n3ncc(C(=O)c4[nH]c5ccccc5c4F)c3N)cc2[nH]1 +NC1CCCN(c2ccncc2Nc2ncc3ccc(-c4cc(C(=O)NC5CC5)ccc4F)nn23)C1 +Cn1cc(-c2ccc3c(c2)CCN3C(=O)Cc2cccc(F)c2)c2c(N)ncnc21 +O=C(Cc1ccc(-n2cnnn2)cc1)N1CCN(CCc2ccc3nonc3c2)CC1 +CCCc1nc(-c2cccnc2)cn2c(CC(=O)NC(CC3CCCCC3)C(O)C3CCCCC3)nnc12 +Cc1cc(C)c(CNC(=O)c2cc(-c3cnn(C)c3)cc(N(C)C3CCC(N)CC3)c2C)c(=O)[nH]1 +CCCCN1CCC(CNC(=O)c2cccc3c2OCCO3)CC1 +CNc1nc2c(N(C)C)ncnc2n1Cc1cccc(NC=O)c1 +COCCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(C)c4)nc2)CC3)n1 +c1cc(C[n+]2ccc(N3CCCCC3)cc2)cc(-c2cccc(C[n+]3ccc(N4CCCCC4)cc3)c2)c1 +CC(C)(C)OC(=O)N1CCN(c2ncc(OCc3ccc(S(C)(=O)=O)cc3)nn2)CC1 +c1ccc(CCN2C3CCC2c2c([nH]c4ccccc24)C3)cc1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C(F)(F)F)nn3)c2)c2cnc(N)nc21 +O=C(NCCN1CCC2(CC1)C(=O)NCN2c1ccc(Cl)cc1)c1ccc2ccccc2c1 +CN(C)CCOc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccon2)cc1 +Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCCCn2ccnc2)cc1Cl +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(C#N)c2OCC2CCCC2)nc1 +O=C(C(=Cc1ccccc1)n1cncn1)c1ccc(Cl)cc1Cl 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+CCCc1c(OCCCCCCc2cccc(OCCCCCCCCC(=O)O)c2CCC(=O)O)ccc2c1OCCC2=O +NC(=O)CC(N)C(=O)NS(=O)(=O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1O +CN1CCC(c2c[nH]c3ccc(NS(=O)(=O)c4cccc5ccccc45)cc23)CC1 +O=C(c1ccc(Oc2ccccc2)cc1)c1cc2c(Cl)c(O)ccc2[nH]1 +O=C(c1ccc(SCc2ccccc2B(O)O)nc1)N(Cc1ccncc1)c1ccc(F)cc1 +Cc1onc(C(=O)N2CCC(Nc3cc(=O)n(C)c4cc(F)c(F)cc34)CC2)c1C +OCc1cnn2cc(-c3c(F)cccc3F)c(-c3ccc(CN4CC(c5n[nH]c(-c6ccccn6)n5)C4)cc3)nc12 +COc1ccc(-c2cc(-c3cccc(NS(C)(=O)=O)c3)nc(N)c2C#N)cc1 +CCCCCC(=O)Nc1ccc2c(c1)C(C)(c1ccccc1)CC(C)(C)N2C(C)=O +Cc1nsc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)n1 +O=C(O)c1ccc2c(C3CCCCC3)c3n(c2c1)CCOc1ccccc1-3 +O=C(NC1CCCC1Nc1ncc(C(F)(F)F)cc1F)c1cc(F)ccc1-c1ncccn1 +Cc1cc(C)n2nc(-c3ccc(S(C)(=O)=O)cc3)c(-c3ccc(F)cc3)c2n1 +CCC1CN2CCc3cc(O)c(OC)cc3C2CC1CC1(O)NCCc2cc(O)c(OC)cc21 +COc1cc(Nc2nc3cc(N)cc(N)c3nc2-c2ccccc2)cc(OC)c1 +Nc1ncnc2scc(C(=O)Nc3ccc(NC(=O)Nc4ccccc4)cc3)c12 +COc1ccc(-c2ccn(CCC(C)(C(=O)NO)S(C)(=O)=O)c(=O)c2)cc1 +CNC(=O)c1nc(C2CC2)ccc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +O=C(NC1CCCCCC1)C(=O)N1CCN(C(c2ccc(Cl)cc2)c2ccccc2Cl)CC1 +O=C(Nc1ccc(CC2CCC(C(O)c3cccnc3)N2)cc1)C1CCc2sc(-c3ccc(F)cc3)nc21 +Cc1nc(NCCC(F)(F)F)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +N#Cc1c(-c2ccc(-c3cccnc3)cc2)nc2ccncc2c1O +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5ccncc5)no4)cc3)cc2)C(=O)NC(=O)NC1=O +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccco2)c1 +CC1(C)CC(Nc2ncnc(NC3CC(O)C(COS(N)(=O)=O)C3)c2F)c2ccccc21 +NS(=O)(=O)c1ccc(C(=O)NNC(=O)Nc2ccc(C34CC5CC(CC(C5)C3)C4)cc2)cc1 +Oc1nc(Oc2cnn(CCN3CCOCC3)c2)nc2cnccc12 +CCc1ccc(S(=O)(=O)NC2c3cc(NC(=O)C4CCCN4Cc4cccc(OC)c4)ccc3CCC2O)cc1 +CCOC(=O)c1cc(F)cc(Nc2cc(NCC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +Cc1oc(S(=O)(=O)Nc2ccccc2)cc1NC(=O)Nc1ccccc1 +CNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4cccc(Cl)c4)ccc3C)CC2)ncn1 +O=C(O)c1cccc(Oc2ccc(CN3CCC(N4C(=O)N(C5CCCCC5)CC4c4ccccc4)CC3)cc2)c1 +O=C(c1nc(-c2c[nH]c3cc(Cl)ccc23)c[nH]1)c1c[nH]c2cc(Cl)ccc12 +CCc1nc2c(-c3ccc(OC)nc3C)ccnc2n1C(C)C1CCC1 +CCOc1ccc(-c2cn3c([n+]2Cc2ccccc2)SCCC3)cc1 +O=C(NC(c1ccc(OC(F)(F)F)c(F)c1)C1CNCCO1)c1ccc2cnc(NC3CCOCC3)nc2c1 +COc1cc2c(Nc3ccc(Cc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1OCCCN1CCOCC1 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CCC(F)(F)C1)CC2 +O=S(=O)(Nc1ccc(CCNCC(O)c2ccccc2)cc1)c1ccc(Cc2nc(CCc3ccccc3)cs2)cc1 +CN(C1CCC(C(N)Cc2cc(F)ccc2F)CC1)S(=O)(=O)c1cccc(C(N)=O)c1 +Cc1cn(C2CC(OCP(=O)(NC(C)C(=O)OC(C)C)Oc3ccccc3)CO2)c(=O)[nH]c1=O +CCOC(=O)CN(C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(C)(C)C +CN(C(=O)Cc1ccccc1Cl)C1CCCCC1N1CCCC1 +CC1Cc2cc(F)ccc2N1C(=O)Cc1nc(N2CCOCC2)c(F)c(=O)[nH]1 +NC(=O)c1cccnc1COc1cc(-c2ccc3c(c2)CCNC3=O)cc2ncccc12 +CC(C)CC(NC(=O)Cc1ccc2c(c1)OCO2)C(=O)NC1CCN(Cc2ccc(OCCCN(C)C)cc2)C1 +Cc1cc(-n2[nH]c3c(cnc4cc(Cl)ccc43)c2=O)cs1 +COC(=O)c1ccc(NC(=O)CN2CCC(Nc3cc(Oc4c(C)cc(C)cc4C)n4ncnc4n3)CC2)c(Cl)c1 +COc1cccc2[nH]cc(CN3CCC(n4c(=O)[nH]c5ccccc54)CC3)c12 +COc1cc(-c2cc(NC(=O)Nc3cc(OCCN4CCOCC4)ccc3C)cc(OC)c2OC)ccc1C(C)=O +CC(C)CNC(=O)c1ccc(-c2ccc(C#CCO)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +CNC(=O)C(NC(=O)C(CCc1ccccc1)CP(=O)(O)Cc1ccc(Cc2cccc(F)c2)cc1)C(C)(C)C +CCN1C(C)CN(c2cc3c(cc2OC)CCN3C(=O)c2ccc(-c3cccc(C)n3)c3ccccc23)CC1C +Cc1cc(CNC(CO)C(=O)O)c(OCc2cccc(C#N)c2)cc1OCc1cccc(-c2ccc3c(c2)OCCO3)c1C +CNc1nc(NCCCN(C)C)c2sc(-c3ccc(N4CCNCC4)cc3)cc2n1 +O=C(O)c1cc(C(F)(F)F)ccc1N1CCC(OCC2CC2)C1 +CC(=O)NCC(=O)N1CCC2(CC1)CCN(Cc1cccc(C(F)(F)F)c1)c1ccccc1O2 +O=c1c2cnc3cccc(O)c3c2[nH]n1-c1ccccc1 +CC(=O)NC12CC3CC(C1)C(OC(=O)N1CCC(NC(=O)OC(C)(C)C)C1)C(C3)C2 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1c(Cl)cccc1Cl +CC(C)=CCCC(C)=CCCCCCCC(P(C)(=O)O)P(=O)(O)O +Cc1csc(-c2nc(N)nc3c2nnn3Cc2ccccc2F)n1 +CCCC1(CC(=O)O)OCCc2c1[nH]c1c(C)c(OCc3cnccn3)cc(C#N)c21 +Cc1ccccc1OC(CCN1CCC(n2c(O)nc3ccccc32)CC1)C(C)C +O=C1NCC2=C1C(c1ccc(F)c(Br)c1)C1=C(O)CCCC1=N2 +CC1CCC2C(CSc3ccccc3)C(=O)OC3OC4(C)CCC1C32OO4 +O=C(NCCc1ccccc1)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 +COc1cc(N)c(Cl)cc1C(=O)NCC1CC[N+]2(C)CCCC12 +CC(c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-c3c(C(=O)N(C)C)sc4c(C)ccc(C)c34)cc2)cc1 +CC(O)(CC(=O)OC(C)(C)C)CC(O)CSc1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)[nH]1 +O=C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)Nc1ccc(Cc2nnn[nH]2)cc1 +CC(C)c1ccc(S(=O)(=O)c2n[nH]c3ccc(NC4CCNCC4)cc23)cc1 +Cc1cccc(C)c1NC(=O)c1ccc(-c2ccccc2)o1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1ccc(F)cc1F)Oc1ccccc1-3 +COc1ccc(Cn2c(N3CCNCC3)nc3ccccc32)cc1 +CCOc1ccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(CCN3CCOCC3)C2=O)cc1 +CCS(=O)(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(S(C)(=O)=O)cc2)[nH]1 +O=C(C=Cc1c(C(=O)O)[nH]c2c(Cl)cccc12)Nc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 +O=S(=O)(c1ccc(CNCCc2ccc(Cl)cc2Cl)cc1)N(Cc1c[nH]cn1)CC1CCCCC1 +N#Cc1nc(NCc2ccc(Cl)c(Cl)c2)c2ncn(Cc3ccccc3)c2n1 +COc1ccc(-c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)cc1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(C#CCO)ccn23)c1 +Cc1cc(C)cc(Sc2c(Cn3cnc(C)n3)c(C)[nH]c(=O)c2I)c1 +CCc1ccccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCCNC2)c1O +O=C(Cc1c(Cl)ccc(NCC(F)(F)c2ccccn2)[n+]1[O-])NCc1ncccc1F +COc1cc(-c2ccc3ncnc(Nc4cccc([N+](=O)[O-])c4)c3c2)ccc1O +CC(C1=C(CCN(C)Cc2nccs2)Cc2ccccc21)c1cnccn1 +COc1ccc(NCCNC(=O)C(CC2CCCCC2)NC(=O)C2CCN(c3ncc(Br)cn3)CC2)cc1 +CNC(=O)N1CCC(N2C(=O)c3cc(-c4cnc(OC)nc4OC)n(C(C)C)c3C2c2ccc(Cl)cc2)CC1 +COc1ccc2nc(NC(=O)CN3CCN(CCCN(C)C)CC3)sc2c1 +COc1cc(C#Cc2cn(C3CCN(C(=O)C#CC(C)(C)O)C3)c3ncnc(N)c23)cc(OC)c1 +Oc1ncn(-c2ccc(-c3c(CCc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cc2)n1 +COc1cc(C(=O)OCCCN2CCCCC2)c2ccccc2n1 +CC(C)(C)OC(=O)c1ccc(-c2cc(-c3cccnc3)c3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1 +CC(C)c1ccccc1COc1ccc(S(=O)(=O)N2CC(O)CCC2C(=O)NO)cc1 +Cn1cc(-c2cnn3c(N)c(Br)c(C4CNCCO4)nc23)cn1 +COC(=O)Nc1nc2cc([S+]([O-])c3ccccc3)ccc2[nH]1 +COc1ccc(S(=O)(=O)N=C(N=C(C)N)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)cc1 +COc1cc(Nc2nc3cccc(-c4c(F)cccc4OC(C)C)c3o2)cc(OC)c1OC +CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)c1nnc(CCCc2c[nH]c3ccccc23)n1Cc1ccccc1 +COCCC1CC1c1cncc(N2CC3CN(C)CC3C2)c1 +COc1cc(OCc2csc(C3CCN(S(=O)(=O)c4ccccc4)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Oc1ccc2c(Oc3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(F)cc3)sc2c1 +O=C(O)Cc1cc(Br)c(Oc2ccc(O)c(Oc3ccccc3C(F)(F)F)c2)c(Br)c1 +Fc1cc(F)cc(Nc2nc3c(-c4nnc[nH]4)cccc3c3sccc23)c1 +Cc1cc(C)cc(C(=O)N2CCC(NCc3cccc4ccccc34)CC2Cc2ccccc2)c1 +c1cc(-c2cnc3ncc(-c4cn[nH]c4)cn23)n[nH]1 +Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(CCCc1ccccc1)CC2 +Cc1cc(C)cc(C(=O)N2CCC(NCc3ccnc4ccccc34)CC2CCc2ccccc2)c1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(OC(=O)OC(C)(C)C)c2)c1 +COc1ccc(C(CC(C)C)NC(=O)c2cc(COc3ccccc3)ccc2CCC(=O)O)cc1F +NC(=O)c1ccc(CC(N)C(=O)N2CCCCC2c2nc(-c3ccccc3)c[nH]2)cc1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(Cc3ccc(C(F)(F)F)cc3)CC2)CC1 +CCOc1ccnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +N#Cc1ccc(-c2ccc3cc(CCC4CCNC4)ccc3c2)cc1 +COc1ccc(S(=O)(=O)NC(C)CCN2CCN(c3ccc(F)cc3)CC2)cc1 +CC(=O)N1CCC(NC(=O)CC2C(=O)NC=CN2S(=O)(=O)c2ccc(C)cc2)c2ccccc21 +Cc1ccc2sc(COC(=O)NC3C(=O)OC3C)cc2c1 +CCN(CC)c1ccc2nc3ccc(N4CCOCC4)cc3[o+]c2c1 +Cc1cnc(NC(=O)C(COC2CCC2)Oc2ncnc3c2cnn3-c2ccccc2Cl)cn1 +O=C(NC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)C(S)Cc1ccccc1 +Nc1ccc(-c2cccc(F)c2)cc1NC(=O)c1ccc(CNc2ccncc2)cc1 +Cc1ccc(CN2CCCC(COc3ccc(-c4nc5cc(C(N)=O)ccc5[nH]4)cc3)C2)cc1 +Fc1cc(-c2nc(N3CCN(c4ncccc4C(F)(F)F)CC3)[nH]c2-c2cc(F)c(F)c(F)c2)cc(F)c1F +O=C(O)CCC=CCC1COC(c2cccs2)OC1c1cccnc1 +Cc1ccc(NC(=O)C2CCN(C)CC2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COc1ccc(C(=O)C=Cc2ccc(C(=O)OC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)cc1OC +Nc1ncnc2c(CN3CC(O)C(CSCc4ccccc4)C3)c[nH]c12 +C=CCCCN(C)C1CCC2(C)C(C(C)CCCC(C)C)CCC2(C)C1O +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C(F)F +Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2cc(F)c(F)c(F)c2)c2cc[nH]c2c1=O +Cc1ccc(CN2CCC(F)(F)C(CCc3ccccc3)C2)cc1C +Cn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2-c2ccc(F)nc2)CC1 +C=CCNc1nc(N2CCC(NCC3c4ccccc4N(CCC)S(=O)(=O)c4ccccc43)CC2)nc2c1ncn2CC=C +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cccc(Cl)c3F)ccc2[nH]1 +O=C(C1CCCN(c2ccc3nc(-c4ccnc(C5CC5)n4)[nH]c3n2)C1)N1CCC(F)C1 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+CCCCN(c1cccc(-c2ccc(Cl)cc2)c1C)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(F)c1F +N#Cc1ccc(CN(Cc2nc3c(c(=O)[nH]2)COCC3)C(=O)CN2CCC(C(=O)c3ccc(F)cc3)CC2)s1 +Cc1ccc(OCc2cc(C)c3c(c2)CCN(CC2COCCO2)C3)c(-c2csc(N3CCC4(C(=O)O)CC4C3)n2)c1 +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCCCc1ccccc1OCC(O)CO +O=C(CN1CCNCC1)Nc1ccc(-c2cccn3c(=O)cc(N4CCOCC4)nc23)c2sc3ccccc3c12 +O=C(CCCl)NCC1OC(n2cc(Cc3ccc(C4CC4)cc3)c3c(Cl)cccc32)C(O)C(O)C1O +COc1ccc(C(=O)N2CCOCC2Cc2cc(-n3nccn3)ccc2F)c(-n2nccn2)c1 +CCCCC1CN(C(=O)c2cccc3ccccc23)CCN1Cc1cncn1Cc1ccc(C#N)cc1 +CCCCC1(CC)CS(=O)(=O)c2cc(CN(O)CC(=O)O)c(OC)cc2C(c2ccccc2)N1 +N#Cc1ccc(CNC(=O)CCOCCN2CCN(c3cccnc3-c3ccccc3)CC2)cc1 +CCCCCN=c1ccn(Cc2ccc(Cl)cc2)c2c(F)cccc12 +C=CC(=O)NC1CCC(N2C(=O)N(Cc3ccccc3)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)CC1 +CCCSCCCNC12Cc3c([nH]c4ccccc34)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5 +O=C(C1=Cc2cc(Br)ccc2S1(=O)=O)N1CCCCC1 +CCCCCCCCCCCCCCC1C(=O)OC(CO)C1OC(C)=O +COC(=O)Nc1ccc2c(c1)NC(=O)CC(C)CCCC(NC(=O)c1c(F)cc(C)cc1F)c1nc-2c(Cl)[nH]1 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+O=C(Nc1ccccc1)N1CCC(Nc2cc[nH]c(=O)c2-c2nc3ccccc3[nH]2)CC1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)nc2ccc(-c3cccc(CN(C)C)c3)cc2c1=O +COc1ccc(C=C2SC(c3ccccc3Cl)=NC2=O)cc1 +O=C(Nc1nc(-c2ccncc2)cs1)NC(c1ccccc1)c1ccccc1 +Nn1c(SCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2cc([N+](=O)[O-])ccc2c1=O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)OCc4ccccc4)nc23)N1 +O=C(NC(Cc1cccnc1)C(=O)NC1C(=O)N2CCS(=O)(=O)C12)OCc1ccccc1 +CC1(C)C2CCC(CCN3C4CCC3CC(n3c(=O)c(C(=O)O)nc5ccccc53)C4)C1C2 +Cc1ccn(-c2ccc(C(=O)N3Cc4cccnc4Nc4ccccc43)c(Br)c2)n1 +O=C(NO)c1cnc(N2CC3C(C2)C3NCc2ccc(Cl)cc2)nc1 +Cc1ccc(C(CNC(=O)c2ccccc2C)CC(C)C)cn1 +NC(=O)c1ccc(NC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)cc1 +NC(=O)c1nn(-c2ccc3onc(N)c3c2)c2c(F)c(-c3ccc(N4CCCCC4=O)cc3F)ccc12 +COc1cc2oc(-c3ccc(O)c(O)c3)c(OC)c(=O)c2c(O)c1O +CSc1nnc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)n1 +Cc1ccc(CN2C3CCC2CC(=CCOC(c2ccccc2)c2ccccc2)C3)cc1 +CCN(CC)CCc1c[nH]c2ccc(NS(=O)(=O)c3cccc4c(Cl)cccc34)cc12 +CCC(CN(c1ccccc1F)S(C)(=O)=O)N1C(=O)C(CC(=O)O)OC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CCNCC(C)(C)COc1cccc2ccc(-c3nnc4ccccn34)nc12 +O=C(OCc1ccccc1)N1CCCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +O=C(Nc1ccc(C(=O)N2CC3CSCCN3Cc3cccc(Cl)c32)cc1)c1ccccc1-c1ccccc1 +COc1cc(OCc2cccc(-c3cnn(C)c3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CN1CC(CO)C=C2c3cccc4[nH]cc(c34)CC21 +Cc1cccc(Cl)c1Nc1nc2cc3c(cc2n2cncc12)OCCO3 +CC1(C)CCC(C(N)=O)N1C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 +CC(=O)OCC1OC(CC(=O)C=Cc2ccc(Cl)c(Cl)c2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +Nc1nc(N2CCN(Cc3c(Cl)cncc3Cl)CC2)nc2nc(-c3ccco3)nn12 +Nc1ccncc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1 +CCc1nn(C2CCCC2)c2c1CCn1c(-c3ccccc3OC)nnc1-2 +CNC(=O)N1CC=C(c2cc3c(-c4cccc(F)c4F)ccnc3[nH]2)CC1 +O=C(Nc1cccnc1)c1cc(Br)ccc1OCc1ccccc1F +CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC(CC)(CC)CC2 +CC1CN(Cc2cccn2S(=O)(=O)c2ccccc2)CCC1(C)c1cccc(C(N)=O)c1 +CCc1nnc2n1CCN(C(=O)c1cccc(C(F)(F)F)c1Cl)C2 +NC(=NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)c1ccccc1F +CC(c1ccc(-c2ccc(=O)n(C)n2)cc1)N1CCC(CC(C)(C)O)(c2ccc(F)cc2)OC1=O +CC1(c2cc(NC(=O)c3ncc(Cl)cc3F)ccc2F)N=C(N)OCC1F +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cn5cnc6ncccc65)C4)cc23)ccn1 +O=C(Cc1cccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)c1)NN1CCNCC1 +Cc1ccc(C(=O)Nc2ccc(C(=O)N3CCCC3C(N)=O)cc2)cc1 +O=C1N(Cc2ccccc2)c2cscc2S(=O)(=O)N1Cc1ccccn1 +Nc1c(S(=O)(=O)O)cc(Nc2cccc3ccccc23)c2c1C(=O)c1ccccc1C2=O +CC(C)n1c(-c2ccnc(N)c2)nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +Cn1cc(-c2cnc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +CCN(CC)Cc1cccc(C=Cc2nc3ccc(F)cc3c(=O)n2-c2ccccc2Cl)n1 +Cn1cncc1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 +Cc1c(C(=O)Nc2cccc(F)c2)nnn1-c1ccc(C(C)C)cc1 +COc1cc2c(cc1OC)C(=O)C(C1CC[N+](C)(Cc3ccccc3)CC1)=C2 +CCC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(C)c1)CC1CCC(C(=O)O)CC1 +CSc1ccc(CN(C)CCOc2ccc(NC(=O)c3cccc4c(O)c5ccccc5nc34)cc2)cc1 +COc1cc2c(Nc3cc(Cl)c(Cl)cc3F)ncnc2cc1OC1CC2OCC(OC)C2O1 +Cc1cccc(C2=NC(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)C(=O)Nc3ccccc32)c1 +CC=CCCC1C(C(=O)O)C(c2ccc3c(c2)OCO3)CN1CC(=O)N(CCCC)CCCC 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+COc1cc(-c2cc(F)cc(F)c2)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +Fc1ccc(C(Cc2ccccc2OC(F)(F)F)N2CCNCC2)cc1 +O=C(NC(=S)NCCC1CCN(Cc2ccccc2)CC1)c1ccccc1[N+](=O)[O-] +CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C#N +O=S(=O)(c1ccc(-c2ccc3c(Nc4ccc(OCc5ccccc5)c(Cl)c4)cnnc3c2)cc1)N1CCOCC1 +CN(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)CCC1c2ccccc2-c2ccccc21 +CCCc1nc2c(C)cc(C(=O)NCCc3ccc(F)cc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1ccccc1Nc1ncc(C(=O)NCc2ccccc2)c(C(F)(F)F)n1 +O=C(O)COc1ccc(-c2ccc(Cl)cc2)cc1C(=O)c1cnn(-c2ccccc2)c1 +CCc1c(C)nc(N2CCN(c3ccccc3F)CC2)nc1O +Cc1cc(S(=O)(=O)NC(=N)Nc2ccccc2S(N)(=O)=O)c(SCc2ccccc2)cc1Cl +CNCc1cn2c(-c3c[nH]c4ccccc34)cc(-c3ccc(F)cc3Cl)c(C#N)c2n1 +CN=C(S)C1c2cc([N+](=O)[O-])ccc2OC(C)(C)C1O +OC1CCN(C2(c3cc4ccccc4s3)CCCCC2)CC1 +CC12CCC(O)CC1CCC1C3CC4OC5(CC(C)(C)C(C)(C)O5)C(C)(O)C4C3(C)CC(O)C12 +Oc1nc2ccccc2cc1C(C#CC1CC1)(OCc1ccccc1)C(F)(F)F +Oc1cccc(Nc2nc(-c3ccccc3)nc3ccccc23)c1 +COc1ccc(-c2nc(O)n(C3CCN(Cc4ccccc4)CC3)c2C)cc1 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+CN(C)C1(C(=O)Nc2cccc(-n3ccnc3)c2)CCN(c2ncnc3[nH]c4c(c23)CCCC4)CC1 +COc1ccc(Nc2nc(N)c(N=O)c(OCC3CCCCC3)n2)cc1 +CCc1nnc(NC(=O)C2(CC(CCc3ccccc3)C(=O)O)CCCC2)s1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCC(C)F +CC(C)NC(=N)c1ccc(OCc2ccc3c(COc4ccc(C(=N)NC(C)C)cc4)cccc3c2)cc1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC1CCC(=O)NCCCC(O)C(O)C(CC2CCCCC2)NC1=O +COCC1CCCN1c1nc(Nc2ccc(-c3cnco3)c(OC)c2)nc(-c2ccccc2)n1 +CC1(CS(=O)(=O)c2ccc(Cl)cc2)COC2(CCCC2)OO1 +COc1ccc(Cl)cc1CNc1ncnc2c1ncn2C1OC(CO)C(CN)C1O +CCc1ccc(-n2cnc3c(sc4nccc(NC)c43)c2=O)cc1 +O=C1CC(c2ccc(O)cc2)Oc2c1ccc1ccccc21 +CCOC(=O)N(C)CC1=Cc2ccc(NC(=O)c3ccc(-c4ccc(Cl)cc4)cc3)cc2CC1 +Clc1ccc(CCC2(Cn3ccnc3)OCC(CSc3ccc(Br)cc3)O2)cc1 +O=C(NC1CCCCC1NS(=O)(=O)c1ccc(-n2ccccc2=O)cc1)c1ccc2c(Cl)c[nH]c2c1 +Cc1cc(NC(=O)C(C#N)=C(O)C2CC2)ccc1OC(F)(F)F +CC(C)n1ncc2cc(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)ccc21 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cccc(C)c2[nH]1)C(F)(F)F +O=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1nc(Cl)c(Cl)[nH]1 +NCc1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)s1 +CC1CC2C(C1)C2(c1ccc(F)cc1)N1CCN(c2ccccc2)CC1 +CC1(c2sc(-c3cncc(C#N)c3)cc2Cl)CS(=O)(=O)C2(CCOCC2)C(=N)N1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)NCc2ccncc2)c1=O)C(=O)C(F)(F)F +CCCn1c(=O)c2nc(-c3ccc(C#N)cc3)[nH]c2n(C)c1=O +OC1(CCCc2cccnc2)CCN(CC2CN(CC3CCCCC3)CC2c2ccccc2)CC1 +CC(C)c1onc(-c2ccccc2Cl)c1C(=O)N(C)c1ccc(Cl)cc1 +O=C(Nc1cc(-c2cc3c([nH]2)C2(CCCNC2)CNC3=O)ccn1)c1cccc(F)c1 +CN1CCN(Cc2cc3cc(-n4cnc5cc(-c6ccc(Cl)cc6)sc5c4=O)ccc3s2)CC1 +N#Cc1ccc(CC(=O)Nc2cncc(C(=O)c3cn(C4(CO)CC4)c4ncncc34)c2)cc1 +Cc1cn(-c2cc(NC(=O)c3ccc(C)c(Nc4nc(-c5cccnc5)cs4)c3)cc(C(C)C)c2)cn1 +COc1ccc(-c2oc3c(O)c(O)ccc3c(=O)c2O)cc1OC +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C1CCCC1)CC2 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCN(Cc2cccc3c2ccn3C)C1 +O=C1C(=O)N(CCCn2cc(COc3ccc(C=NNc4ccnc5cc(Cl)ccc45)cc3)nn2)c2ccc(F)cc21 +N#CC1CCCN1C(=O)CNC1CCN(c2ccc(C(F)(F)F)cn2)CC1 +Cc1cc(C)c(NC(=O)N(Cc2ccc(-n3ccnc3)cc2)C2CCCCCC2)c(C)c1 +O=S(=O)(NCCCN1CCN(c2nsc3ccccc23)CC1)c1cccc2scnc12 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(C(=O)O)n(C)c(=O)c3ccccc23)cc1 +COc1ccc(-c2cnc3c(N(C)C)snc3c2)cc1OC +O=C(Nc1cccc(-c2cccnc2)c1)N(CCC(c1ccccc1)c1ccccc1)CCN1CCOCC1 +COc1cc(OCc2csc(C3(c4cccc(Cl)c4)CCOCC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(c1cccc2cc(N=C=S)ccc12)c1cn(CCN2CCOCC2)c2ccccc12 +O=C(O)c1ccc2c(c1)C(=CCn1cnc3cc(C(=O)NCc4ccccc4)ccc31)c1ccccc1CO2 +COc1cc(NC(=O)c2nn3c(C(F)(F)F)cc(-c4ccc(Br)cc4)nc3c2Cl)cc([N+](=O)[O-])c1 +c1ccc(COc2cccc(C3CC(c4ccc5c(c4)OCCO5)=NN3c3ccccc3)c2)cc1 +COc1ccc(S(=O)(=O)Nc2c(C)cc(Cl)cc2C)cc1 +CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc3ccc(Cl)cc23)c1 +CCCCCCCCCCC1(C(=O)Nc2c(C)ccc3c2OCCC3=O)CCCC1 +COc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1c(C)[nH]c3ccccc13)CC2 +CCN(C(=O)SCC(=O)Nc1ccc(-c2ccc(CC(=O)O)cc2)cc1Cl)c1ccc(C(C)(C)C)cc1Cl +CS(=O)(=O)Nc1ccccc1-c1ccc2[nH]c(C=Cc3ccc(C(F)(F)F)cc3)nc2c1 +CN(C)c1ccc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)cn1 +COc1cc(Nc2cc(-c3ccccc3)nc3c2C(=O)NCC3)ccc1C(=O)O +CC1C(c2ccc3c(c2)NC(=O)CO3)=C(c2ccc(F)cc2)C(=O)N1C 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+COc1ccc2[nH]cc(CC(=O)N3CCN(c4scnc4-c4nc5ccccc5[nH]4)CC3C)c2c1 +CCOc1ccc(C2=NN(c3ccc(C(=O)O)cc3)C(=O)C3CC=CCC23)cc1OCC +CN1C(=O)N(c2ccnn2C)CC1C(=O)NCc1ccc(Cl)cc1Cl +O=C(O)c1nc2c(=O)[nH]c3cc(Cl)c(-n4cccn4)cc3n2n1 +O=C(Nc1ccc(I)cc1)Oc1ccc2c(c1)C13CCCCC1C(C2)N(CC1CCC1)CC3 +CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2cccc(CNC(=O)CNS(C)(=O)=O)c2)n1 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)CCCc4ccccc4)c3)cc12 +N#Cc1cc(Oc2ccc(-c3cc(C(O)CO)cc(C(N)=O)n3)cc2)ccc1C(F)(F)F +O=C(Nc1ccc(C(F)(F)F)cn1)N1CC=C(c2ncc(-c3nnc(CO)o3)cc2Cl)CC1 +CC(=O)Nc1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)cc(C(F)(F)F)c1 +OC1CCN(Cc2cnc3cc(Oc4ccc(-c5ccn[nH]5)cn4)ccc3c2)C1 +O=C(O)c1cccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2sc3ccccc3c2Br)c1 +O=C(O)C1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(OC(F)(F)F)cc1 +Cc1ccc2c(OCCN3CCC(Cc4cccc(NC(=O)C(C)C)c4)CC3)cccc2n1 +O=C(NCc1cc([N+](=O)[O-])ccc1O)c1cccnc1Sc1ccccc1Cl +O=C(Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)C1CC1c1cccnc1 +CC(C)CC(NC(=O)CC(NC(=O)c1ccc2ccccc2c1)c1cccc(Cl)c1)B(O)O 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+O=C(O)CC(NC(=O)CN1CCN(CCc2ccc3c(n2)NCCC3)C1=O)c1cccnc1 +FC(F)(F)Oc1ccc(CN2CCC3(CC2)OC(c2cc(Cl)cc(Cl)c2)c2ccccc23)cc1 +CN1CCN(Cc2cccc(C(=O)C=Cc3cccc(C=CC(=O)NO)c3)c2)CC1 +Cc1cc(S(=O)(=O)NC(=N)NCc2ccc(S(N)(=O)=O)cc2)c(SCc2cc3c(cc2Cl)OCO3)cc1Cl +O=c1sc2ccccc2n1CCCCCCN1CCN(CCCCCCn2c(=O)sc3ccccc32)CC1 +CCCC(C(=O)O)c1c(C)nc2sc3c(c2c1-c1ccc(C(F)(F)F)cc1)CCC3 +Cn1c(=O)c2nc(-c3ccccc3)[nH]c2n(C)c1=S +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cccc(N2CCC(O)(C(F)(F)F)CC2)n1 +CN1CC2CC1CN2c1ccc(-c2ccc3[nH]ccc3c2)cn1 +CC(=O)NC(C)c1ccc(OC2CCN(c3cc(OCC4CC4)ncc3C)C2)cc1 +CC(Nc1ncnc(N)c1C#Cc1ccccc1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +COc1cc2c(cc1OCc1ccncc1)Cc1c-2n[nH]c1-c1ccc(C#N)cc1 +CC(C)Cc1cc2c(cc1Cl)C=C(C(=O)O)C(C(F)(F)F)O2 +Cn1cncc1C(O)(c1ccc2nc(Cl)c(Cc3ccc(-n4cccn4)cc3)c(Cl)c2c1)c1cncs1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(F)c1F +CCC(CO)Nc1nc(NCc2cccc(OC)c2OC)c2ncn(C(C)C)c2n1 +Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NCc2ccccn2)C3)c1-c1ccc(C(F)(F)F)cc1 +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4cc(O)c(OC)cc4[nH]3)CC3CC123 +OC1C(CNCCOc2ccccc2)CCC1(c1ccccc1)c1ccccc1 +CN(C)C(=N)c1ccc(C(=O)Nc2ccccc2C(=O)Nc2ccc(Cl)cn2)cc1 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc3c(c2n1Cc1ccccc1)CCC3 +CN1Cc2ccc(Nc3nccc(-c4cnc(N5CCC(F)C5)c(C#N)c4)n3)cc2C1 +CCC1(CCCCN2CCN(c3ccc(Cl)cc3)CC2)C(=O)Nc2ccccc21 +CCc1nc(NC2CCCC2C#N)c2cc[nH]c(=O)c2n1 +CCN(Cc1cc(F)ccc1-c1cn(CC(=O)O)c2ccc(C(F)(F)F)cc12)C(=O)C1CC1 +N#CC1(CCCN2CCC(O)(c3ccc(Cl)cc3)CC2)c2ccccc2C[S+]([O-])c2ccccc21 +Cc1cccc(F)c1CN1CC(c2ccc(N3CCC(C(=O)N(C)C)CC3)cc2)C(N(C)C)C1 +CSc1nc(C=C(C)C2CC3OC3(C)CCCC(C)C(O)C(C)C(=O)C(C)(C)C(O)CC(=O)O2)cs1 +CCc1ccc(Cc2cc(C3SC(CO)C(O)C(O)C3O)ccc2Cl)cc1 +COC(C)C(=O)N(c1ccccc1Cl)C1CCN(CCc2ccccc2)CC1C +Cc1nccn1CCCCc1ccc(CC(=O)NC(CO)C(=O)NC(CNC(=O)CN)C(=O)NCCC2CCCCC2)cc1 +COc1ccc2c(c1)CC(C(=O)NC(C(=O)NC(CCc1ccccc1)C(=O)NCc1ccc(C)cc1)C(C)O)CC2 +CCNC(=O)C1OC(n2cnc3c(NC(=O)Nc4ccc(F)cc4)ncnc32)C(O)C1O +O=C(NCc1ccc(F)cc1)c1cn2c(c(O)c1=O)C(=O)N1CCCN(Cc3nccs3)C1C2 +O=C1CCC(C(=O)NC(CCCCCS)C(=O)Nc2ccccc2)N1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCCCCN(C)C13CC4CC(C)(CC(C)(C4)C1)C3)C2 +CNC(=O)C(C#N)NC(=O)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +CN1C(=O)CCc2cc(-c3cccnc3)c(OC3CCCC3)cc21 +CSc1nc(-c2cc(OCCN3CCCC3)c(Cl)cc2Cl)c2c(C#N)c[nH]c2n1 +Cc1ccc(Sc2ccc3c(-c4c(Cl)cccc4Cl)c(=O)ncn3n2)c(C)c1 +CCNC(=O)C1OC(n2cnc3c(NC(C)Cc4ccccc4)ncnc32)C(O)C1O +CCOc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(CC)cc2C)[nH]1 +O=[N+]([O-])C1C(c2ccccc2Br)CCN(Cc2cccnc2)C1c1ccc(O)cc1 +CC(C=CC(C)=CC1Cc2nc(cs2)CCCCC(=O)OC(C)CC(C)=CC=CC(=O)O1)=CCN(C)C +NC(=O)c1nc(Nc2ccc3ccc(F)cc3c2)sc1NC(=O)C1CC1 +CC(C)Cc1ccc(-c2cc3cn(C4CC(O)C(CO)O4)c(=O)nc3o2)cc1 +CN(C)c1ccc(NC(=O)Nc2ccc(OS(N)(=O)=O)cc2)cc1 +OC(COc1ccccc1)CN1CCC2(CC1)OCc1c2ccc2ccccc12 +N#CC1CCCCC1n1cc(C(N)=O)c(Nc2ccc(S(=O)(=O)NCCN3CCCC3)cc2)n1 +O=c1cc(C=Cc2ccc(C(F)(F)F)cc2)c2cc(C(c3ccc(Cl)cc3)c3nccs3)ccc2[nH]1 +CC(C)CC(=O)NCc1cnc2c(cnn2-c2cc(NC(C)C)c(C(=O)NCC(F)C(C)(C)O)cn2)c1 +COc1ccc(N2C(=O)C(=Cc3cc(F)c(O)c(Cl)c3)OC2=S)cc1 +C[N+]1(CCCOc2ccccc2)CCC(N2CC(c3ccccc3)(c3ccccc3)NC2=O)C1 +COCC(C1CC1)n1nc(C)nc(Nc2c(Cl)cc(C(F)(F)F)cc2Cl)c1=O +COc1ccc(S(=O)(=O)N(Cc2ccccc2)c2c(C)cc(C)cc2C(=O)NO)cc1 +NS(=O)(=O)c1ccc(O)c(NC(=[Se])NC(=O)c2ccc(-c3ccccc3)cc2)c1 +CC(NP(=O)(COC1C=C(F)C(n2cnc3c(N)ncnc32)O1)Oc1ccccc1)C(=O)OC1CCCC1 +O=C(NC1CCCC(NC(=O)c2ccccc2F)C1)c1cccc(Cl)c1 +CC(Oc1nc(-c2ccc3c(c2)C2(CCN(C)CC2)C(=O)N3)cnc1N)c1c(Cl)ccc(F)c1Cl +CN1CCN(c2cccc(CNCCc3ccc(NC(=O)Nc4cnc(C#N)cn4)cc3Cl)c2)CC1 +N#Cc1nc(NC2CC3CCC2C3)c(N)c(N2CCOCC2)n1 +CC(C)(C)c1ccc(S(=O)(=O)CCNc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1cc(NC(=O)c2ccc(C3CCCN3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C +COc1cc2c(cc1O)CCC1C2CCC2(C)C(c3cccnc3)CCC12 +CC(C)Cn1c2ccc(C(=O)c3sccc3Cl)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +CC(NS(=O)(=O)CCCn1ccc(=O)[nH]c1=O)c1ccc(F)c(OCC2CC2)c1 +CCOC(=O)C=CC(=O)N(CC(N)=O)NC(=O)C1CCCN1C(=O)C1CCCCN1C(C)=O +Cc1ccc(-c2nn(-c3ccccc3)cc2C(=O)Nc2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)cc1 +FC(F)(F)C1(c2nnc(-c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3Cn3cncn3)s2)CC1 +CCCc1c(Cc2ccc(-c3ccccc3-c3nc(=O)o[nH]3)cc2)c(=O)n(C2CCC(OC)CC2)c2ncnn12 +COc1cc(Cl)ccc1-c1nc(NCCNc2ccc([N+](=O)[O-])c(N)n2)ncc1-c1ncc[nH]1 +O=C1N(Cc2ccccc2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc2ccccc2c1 +CCC(C)C1=NC2CC=C3CC4C(=O)CC5(C)C(C(C)N(C)C)C(O)CC5(C)C4CCC3C2(C)CN1 +CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(F)c[n+]3[O-])c2)CC1 +CNC(=O)Nc1ccc(Oc2ncnc(N)c2C=NOC)c(F)c1 +Cc1ccc(O)cc1Nc1cc(C(F)(F)F)nc(-c2cccnc2)n1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CC3)CC2)c1)c1ccc(F)cn1 +CC(=O)NC1CCN(CC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)C1 +CC1CN(c2nc(N3CCOCC3)c3sc(-c4cccnc4)cc3n2)CC(C)O1 +CC(Cc1ccccc1)n1c(-c2ncccc2O)nc2ccnc(C(F)(F)F)c2c1=O +O=C(Cn1nnc(-c2ccncc2)c1-c1ccccc1)Nc1cccc(-c2ccccc2)c1 +CCOC(=O)C1=C(C)N=c2sc(=Cc3cc(Br)ccc3O)c(=O)n2C1c1ccc(OC)c(OC)c1 +CN(C)CCN(Cc1ccco1)C(=O)c1cc2c(Cl)nc3ccccc3c2s1 +CC(C)(C(=O)N1CCC(CC(=O)O)CC1)C(NC(=O)c1ccc(C(=N)N)cc1)c1ccc(O)cc1 +c1cc(COc2cccc(-c3nn[nH]n3)c2)cc(OCc2ccc3ccccc3n2)c1 +CCCOc1ncc(C(C)=O)cc1-c1nc(O)c2nn(C3CCN(CC)CC3)c(CC)c2n1 +c1ccc2c(c1)[nH]c1nccc(NCC3CCCCC3)c12 +CCNc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC1=CCC(C(C)=CC=CC(C)(C)O)CCC(C)=CCC1 +O=C(Nc1cc(F)cc(Oc2cc(NC(=O)C3CC3)ncn2)c1)Nc1ccc(Cl)c(C(F)(F)F)c1 +CC(C)n1cc(-c2ncc(N)nc2-c2ccc(F)cc2)ccc1=O +CCn1c(-c2ccnc(Nc3ccc(S(C)(=O)=O)cc3)n2)cnc1C +COc1ccc2nc3cc(Cl)ccc3c(NCCCCCCCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1 +Cc1ncc(C)c(-c2ccc3c(c2)CCC(C)N3C(=O)c2ccc(O)cc2O)n1 +CC(C)(C)c1ccc(-c2noc(CCC(=O)NC3CCCCC3)n2)cc1 +COC(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21 +O=C(c1cc(COc2ccc(F)cc2Cl)on1)N1CCSCC1 +CN1CC(C)(COc2ccc(C(=N)N)cc2)Oc2cc(N(Cc3cc(F)cc(F)c3)C(=O)C(=O)O)ccc21 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2cccc(Cl)c2F)c2cc[nH]c2c1=O +COc1nccc(N(Cc2ccc(C#CCN3CCN(C(C)C)CC3)cc2)CC(C)(C)C)n1 +COc1ccc(NS(=O)(=O)c2cccc([N+](=O)[O-])c2)cc1N1CCN(C)CC1 +Cc1ccc(S(=O)(=O)Oc2cccc3c2CC2CC(C(=O)N4CCN(c5ccc6nsnc6n5)CC4)CN(C)C2C3)cc1 +CCCCCN(C)CNCC(=O)C(CC(=O)O)NC(=O)C(CC)n1cc(C(C)(C)C)nc(NCc2nonc2C)c1=O +Cc1cc2c(cc1-c1cc(CCC(=O)O)ccc1OC(F)(F)F)N(CC(F)(F)F)C(=O)CC2(C)C +CN1CCCC(CN(C)C(=O)Cn2c(-c3ccccc3)c(C3CCCCC3)c3ccc(-c4noc(=O)[nH]4)cc32)C1 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+Cn1c(=O)c2[nH]c(-c3ccc(OCCN4CCCC4)cc3)nc2n(C)c1=O +Nc1ncccc1-c1nc2ccc(-c3cccc(NC(=O)C4CC4)c3)nc2n1-c1ccc(C2(N)CCC2)cc1 +O=C(NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1)c1c(F)cccc1F +Nc1ncnc2c1C(=O)N(c1ccc(C3CCC(CC(=O)N4CC(O)C4)CC3)cc1)CCO2 +COC1CCN(c2nccc(Nc3cc4[nH]c(-c5cn[nH]c5)cc4cn3)n2)CC1 +Cn1c(COP(=O)(NCCBr)NCCBr)cnc1[N+](=O)[O-] +O=C(CNC(=O)c1ccncc1)NC(c1ccccc1)c1ccc(Cl)cc1 +CN(CCBr)P(=O)(OCC1OC(C2C=C(F)C(=O)NC2=O)CC1O)On1nnc2ccccc21 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5ccnn5C)cc4F)nccc3c2Cl)CS1(=O)=O +COc1ccc2[nH]cc(CCNC(=O)CCc3cc[n+](Cc4ccc(F)cc4)cc3)c2c1 +NC(=O)C12CC3CC(C1)C(NC(=O)c1cc(NS(=O)(=O)c4cccc(Cl)c4)ccc1Cl)C(C3)C2 +CCc1cc(NCc2cc3c(nc2OC)CCCC3)c(O)nc1C +NC(CC(=O)N1CCn2nncc2C1)Cc1cc(F)c(F)cc1F +CCCOc1ccc(S(=O)(=O)N2CC(N3CCCCC3)CC2C(=O)NO)cc1 +COc1ccc(-c2cc(CCC(C)(C(=O)NO)S(C)(=O)=O)on2)c(F)c1 +CCN1C(=O)CCC1C(=O)NCc1ccc(F)c(F)c1Cl +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1nnn(CC(C)C)c1C(=O)O +CN1CCN(c2cccc(N(CC3CC3)S(=O)(=O)c3ccc4ccccc4c3)c2)CC1 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+CC(O)C(=O)NC(C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)N1CCCN(C(=O)C2(c3ccccc3)CC2)CC1 +O=C(O)C(C1CCN(C(=O)C=Cc2cc(F)c(F)c(F)c2)CC1)N1CCC(c2c[nH]c3ccc(O)cc23)CC1 +CP1(=O)OCCC2(CCCC3(S(=O)(=O)c4ccc(Cl)cc4)c4c(F)ccc(F)c4OCC23)CO1 +CCCCCCCCCCn1nnnc1NC(=O)Nc1c(C(C)C)cccc1C(C)C +COc1ccc(-c2c(C(F)(F)F)nn3c(=O)cc(-c4cc(F)c(Cl)nc4Cl)[nH]c23)cc1OC +O=C(Nc1cccc(Nc2cc3c(cc2Cl)C(=O)NC3=O)c1)c1cccc(OC(F)(F)F)c1 +COc1cc2c(Nc3cc(Cl)c(Br)cc3F)ncnc2cc1OCC1CN2CCOCC2CO1 +O=C(O)CCc1ccc(C(=O)CNC(=O)c2cc3c(s2)CCNC3)cc1 +CC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(-c5ccsc5)cc34)cn2)CC1 +N#Cc1cc(Cl)c(-c2nc3ccnc(Nc4cc(N)ncn4)c3[nH]2)c(Cl)c1 +CCCCN(CCCC)c1ccc2c(c1)Cc1cc(NC(N)=S)ccc1-2 +CC(=O)N(C)CCn1ccc2cc(C(=O)N3CCC(N4C(=O)OCc5ccccc54)CC3)ccc21 +Cc1ccc(-n2nccn2)c(C(=O)N2CCC3CN(c4nc(C)cc(C)n4)C3C2)c1 +O=C(c1ccc(F)c(F)c1Cl)N1CCN(c2ccc(F)cc2Cl)C(=O)C1 +COc1cc(OCc2cccc(-c3ccc([N+](=O)[O-])nc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(Nc1cnn(C2CCOCC2)c1)c1ccc2cc3n(c2c1)CCCNC3=O 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+OC12CCCCC13CCN(CC1CCC1)C2Cc1ccc(OCCc2ccccc2)cc13 +O=C1OC2(CCN(C(=O)Nc3ncc(-c4cccc(C(F)(F)F)c4)cn3)CC2)c2ccccc21 +CN(C)CCCNC(=O)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCCC(=O)O)no2)cc1C#N +COC(=O)C(c1ccc(F)cc1)N1C(=O)c2cc(Cl)ccc2NC(=S)C1c1ccc(Cl)cc1 +C[S+]([O-])c1ncc(C(=O)Nc2ccc(CCN3CCOCC3)cc2C2=CCCCC2)[nH]1 +Cc1c(-c2ccccc2)n(Cc2ccc(OCCN3CCCCC3)cc2)c2ccc(O)cc12 +CC(C)n1c2nc(-c3ccccc3)nc(=O)c-2[n+]([O-])c2ccccc21 +CN(C)c1ccc(-c2nc3ccc(OCCF)cc3s2)cn1 +CCNC(=O)C1OC(n2cnc3c(Nc4ccc(OCC(=O)NC5CCCCC5)cc4)nc(Cl)nc32)C(O)C1O +CN1OC2(N=C1N)c1cc(-c3cc(Cl)cc(Cl)c3)ccc1CC21CCc2ccccc2CC1 +CNC(=O)c1cccc2c(Nc3cc(N)cc(CO)c3)c3cccc(C)c3nc12 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cn5cc6cccc(F)c6n5)C4)cc23)ccn1 +O=C(O)c1ccc2c(c1)C(=NCc1cccnc1)c1ccccc1CO2 +CNC(=O)C1CC(N)C(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)O1 +CCCN1CCc2cccc3c2C1Cc1cccc(OC(=O)NC(C)(C)C)c1-3 +CNCC1CCC2C(c3cccs3)Nc3ccc(C(C)(C)C)cc3C2O1 +NC(CC(=O)N1CCn2c(nnc2-c2ccncc2)C1)Cc1cc(F)ccc1F +O=C(O)Cc1nn(Cc2nc3cc(C(F)(F)F)ccc3s2)c2ccccc12 +N#CC1(NC(=O)C2CC(S(=O)(=O)c3ccccc3)CC2C(=O)N2CCOCC2)CCC1 +COc1cc2c(cc1OCCCF)CCN1CC(CC(C)C)C(O)CC21 +O=C1NC(=O)C2(N1)OC(COP(=O)(O)O)C(O)C2O +CC1(C)C2CC(CC=CCCCC(=O)O)C(NC(=O)c3ccsc3)C1C2 +C=CCn1ncc2c(NCCC)nc(N3CCC(NCC4c5ccccc5CCc5cc(OC)ccc54)CC3)nc21 +CNCC1C2CCC(C2)C1c1ccc2cc(OC)ccc2c1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1cc(C(F)(F)F)ccc1F +CCn1nc(-c2ccc(C(C)N3CCC(CC(C)(C)O)(c4ccccc4)OC3=O)cc2)ccc1=O +CCCCC1(CCCC)CS(=O)(=O)c2cc(CNC(CC(=O)O)CC(=O)O)c(OC)cc2C(c2ccccc2)N1 +CCOC(=O)C1Nc2cc(Cl)cc(Cl)c2S(=O)(=O)N1Cc1cccc(C)c1 +Cc1nc(C#Cc2cnc(N3CCCC(CO)C3)nc2)cs1 +Cc1ccc2nc(N3CC=CC3)nc(NCc3ccc(NC(=O)C4CCN(Cc5ccccc5)CC4)cc3)c2c1 +Cc1[nH]c(C=C2C(=O)Nc3ccc(C(=O)O)cc32)c(C)c1CCC(=O)O +CCc1ncnc(-c2cc(F)c(C(=O)N3CCN(CC)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +O=C(Nc1ccc(-n2nc(C3CC3)cc2C2CC2)cc1)c1c(Cl)cncc1Cl +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(-n5cccn5)cc4)nc23)N1 +COc1c(-c2ccccc2)[nH]c2c(N3CCCCC3)nc(C)nc12 +Oc1nc2cc3cc(OCCCc4nnnn4C4CCN(CCc5ccccc5)CC4)ccc3[nH]c-2n1 +Cn1c(-c2ccc(O)cc2)nnc1C1(c2ccc(Cl)cc2)CCC1 +CC(C)CCOc1ccc(S(=O)(=O)N(CC(=O)NO)CC(C)C)cc1 +Cc1[nH]c(-c2ccccc2)c(-c2ccccc2)c1C(=O)c1cn(-c2ccc(Cl)cc2)nc1C(=O)Nc1ccccc1 +CCN1c2ncc(COc3cccc([N+](=O)[O-])c3)cc2C(=O)N(C)c2ccc(Cl)nc21 +Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(Cc1ccccc1)c1nnc(C)n1-2 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCCC4CO)nc3n2)cc1CO +Fc1ccc(COCC2CCN(Cc3ccc(Cl)cc3)CC2)cc1 +O=C(c1ccc(F)cc1)C1CCN(CC(=O)N(Cc2ccc(F)cc2)Cc2nc3c(c(=O)[nH]2)COCC3)CC1 +CC(C)N(C)C(=O)n1cnc(S(=O)(=O)C2C3CC4CC(C3)CC2C4)n1 +Cc1c(S(=O)(=O)Nc2ccc(CO)cc2S(C)(=O)=O)sc2ccc(F)cc12 +COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(C(=O)N(C)C)cc4)sc23)c(Cl)cc1Cl +CC(C)(CC(O)(Cc1cc2cc(C#N)ccc2[nH]1)C(F)(F)F)c1cc(S(C)(=O)=O)cc2c1OCC2 +CCCCCCc1cc(=O)oc2[nH]c(=O)[nH]c(=O)c12 +CC(C)(C)C(NC(=O)CCCc1cccnc1)NC(=NC#N)Nc1cccc2ncccc12 +O=C1NCCCN1c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12 +CCCCN(CCCC)S(=O)(=O)CCC(=O)NC(Cc1ccccc1)C(O)CNCc1cccc(OC)c1 +CC(C)(C)c1ccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)s1 +CCCn1c2ccc(NC(=O)OC(C)C)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +COc1nc(NCC#N)nc(-n2c(Nc3cccc(O)c3)nc3ccccc32)n1 +CC(C)(C)S(=O)(=O)NC1CCC(C(=O)Nc2ccc(C(F)(F)F)cn2)CC1 +COCc1cn(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)nn1 +COC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC(C)CN)c2c1C +Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4c(C(=O)NCC6CC6)ncn4-5)CC3)cccc2n1 +COc1ccc2oc(Cc3cccc(C(F)(F)F)c3)c(CCNC(C)=O)c2c1 +CCC1CC2CC(c3cc(F)ccc3F)(S(=O)(=O)c3ccc(Cl)cc3)CCC2NS1(=O)=O +CC(C)(C)c1ccc(-c2c(O)noc2C2CCNCC2)cc1 +COc1cc(C(=O)N2CC(OC)C2)ccc1Nc1ncc2ccnc(NCC(C)(C)OC)c2n1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC1CCN(C(=O)C(CC(C)C)NC(=O)OCc2ccccc2)CC1=O +CCC(NC(=O)c1cc(C(=O)N2CCCC2c2ccn(C)n2)n2c1COCC2)c1ccccc1 +CC(C)=CCN1Cc2cc(Cl)cc3nc([SeH])n(c23)CC1C +COc1cc(OC)c(C(=O)C=Cc2cn(-c3ccccc3)nc2-c2cccnc2)c(OC)c1 +COc1cccc(C=CC(=O)NC2CCC(CCN3Cc4ccc(C#N)cc4C3)CC2)c1 +Cc1nc(N(C)C)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +O=c1ncn2nc(Sc3ccc(F)cc3F)ccc2c1-c1c(Cl)cccc1Cl +CN1CCN(c2nccn3cc(C(=O)N4CCCN(c5ccccn5)CC4)nc23)CC1 +CNCC(C)NC(=O)N1CCCC(C(O)(CCCCOC)c2ccccc2Oc2ccccc2)C1 +Cc1ccc(C(C)(C)CC(O)(Cc2cc3cc(S(C)(=O)=O)ncc3[nH]2)C(F)(F)F)c(C(N)=O)c1 +CNc1nc(Nc2cc3c(cc2Cl)c(C(=O)N(C)C)cn3C)ncc1C(F)(F)F +Clc1ccc2ncc(CCc3n[nH]c(N4CCCC4)n3)nc2c1 +CCCCCn1c(C)c(C2CC2)c(=O)n(CC(=O)NC(C)(C)C)c1=O +N#CC(Cc1ccc2c(cnc3ccccc32)c1)NC(=O)C1NC2CCC1C2 +COc1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3C)cc1CC2 +CCOC(=O)C1=C(c2ccc(-n3c(C)nc4cnccc43)cc2)NC(C)=C(C(=O)Nc2ccccn2)C1c1ccccn1 +CC(Cc1cn2c3c(cccc13)OCCC2)NCC(O)c1cccc(NS(=O)(=O)c2cccs2)c1 +O=C1c2cc(F)cc3cnn(c23)CCN1C1CN2CCC1CC2 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1ncnc2c(N)nc(N3CC4CC3CN4C)nc12 +CNC(=O)c1ccccc1Nc1nc(Nc2ccc(NS(=O)(=O)c3ccc(C)cc3)c(C)c2)ncc1Cl +Cc1c(C(=O)NC2CCCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1c(C)ccc1C +COc1cc(-c2ccc(CC(C)NCC(O)c3ccccc3)cc2)ccc1C(=O)O +Cc1cc(C)cc(NC(=O)NCC(c2ccc(-c3ccccc3)cc2)N2CCN(C3CCCCC3)CC2)c1 +CCOC(O)=C1C(COCCNc2n[s+]([O-])nc2OC)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl 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+COc1cc(NC(=O)N2CCN(c3nc(-c4ccccc4)ns3)CC2)ncn1 +COC(=O)CCCCCCCCCCCCCCC=C1CC(CO)(COC(=O)C(C)(C)C)OC1=O +N#Cc1cc(-c2ccnc(Nc3ccc(NC(=O)CN4CCNCC4)nc3)n2)cnc1N1CCC(F)C1 +O=C(NCCNc1ccc([N+](=O)[O-])c2nonc12)C(=O)c1c(-c2ccc(F)cc2)[nH]c2ccccc12 +Cc1ccc(N2CCN(CCCN3c4cccc5cccc(c45)S3(=O)=O)CC2)cc1 +CN1CCN(c2ccc(Nc3nccc(-c4cnn5ncccc45)n3)cc2)CC1 +CN=C1C(=O)c2ccccc2C(O)=C1N(C(C)=O)c1ccc(Br)cc1 +Cc1cc(CC(OC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)C(=O)N2CCCCC2)cc2cn[nH]c12 +CCCC12CCC(=O)C=C1c1c(cc(OCCCC(=O)O)c(Cl)c1Cl)C2 +Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(CN4CCOCC4)cc3)cc(N(C)C3CCCCC3)c2C)c(=O)[nH]1 +CC(C)(CC(O)(Cc1ccccc1)C(=O)Nc1ccc2c(c1)COC2=O)c1ccccc1 +CC(C)(C)Cc1nc2cc(S(=O)(=O)C3CN(C(N)=O)C3)ccc2n1CCOC(F)(F)F +CN(C(=O)OC1CC2CN(c3ccc(OC(F)(F)F)cc3)C(=O)N2C1)c1cccc(F)c1 +O=C(Cc1ccccc1)Nc1ccc(OC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)CC2)nn1 +CC(C)N1C(=O)c2[nH]c(Cc3ccccc3)nc2N2CC(Cc3ccccc3)N=C21 +CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)ccc2c1OC(C(=O)O)CC2 +Oc1ccc(-c2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2)cc1 +COC(=O)N1CCC(CCC(=O)O)(Cc2cccc(C(CC#N)Nc3nc4nc(C)ccc4[nH]3)c2)CC1 +CCCCN(CC)c1nc(C)nc2c(-c3ccc(OC)cc3C)c(C)nn12 +c1ccc2cc(OCC3CCN(CC4CC4)CC3)ccc2c1 +O=C1N(Cc2ccccc2)C(Cc2ccc3c(c2)CCO3)C(O)C(O)C(Cc2ccc3c(c2)CCO3)N1Cc1ccccc1 +CC1CCC2C(C)(COC(=O)CCc3ccccc3)OC3OC4(C)CCC1C32OO4 +COc1ncc(Nc2ncc(C(C)N3CCN(S(C)(=O)=O)CC3)cc2-c2nc(C)nc(N)n2)cc1F +CCOc1cc(-n2nnc3c(cnn3C)c2=O)c(F)cc1Cl +CN(C)CCOc1cncc(-c2cncc(OCCN(C)C)c2)c1 +CCN1C(=O)c2nc(Br)n(Cc3ccccc3)c2N2CC(Cc3ccccc3)N=C12 +O=C(NCc1ccc(F)cc1)C1C(=O)N(O)C(=O)c2ccc(F)cc21 +CC(CCC(=N)N)C1CCC2(C)C3=C(CCC12C)C1(C)CCC(O)C(C)(C)C1CC3 +CC(Sc1cc(-c2cnn(C3CCOCC3)c2)cnc1N)c1c(Cl)ccc(F)c1Cl +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(OC(=O)OCc2ccccc2)c1 +O=C(O)c1ccc(-c2cc3cccnc3c(-c3cccc([N+](=O)[O-])c3)n2)cc1 +Cc1cc2c(C(=O)NCC3C(C)CCCN3C(=O)c3nc(C)sc3-c3ccccc3)cccc2o1 +CCCCCOc1ccc2c(c1OCCCCC)CN(CCc1ccc(N)cc1)C2=O +Cc1c[nH]c2ncnc(N3CCN(C(=O)C(CN)Cc4ccc(Cl)cc4)CC3)c12 +Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Nc2ccccc2)c1Br +CCCCNc1nc(N2CC(=O)Nc3cc(OC)ccc32)c2ccccc2n1 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+CC(=O)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3SC(C)C)CC2)c(F)c1 +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(C)c3)n3c2CCOC(C)C3)cc(C)n1 +NC(CNC(=O)c1ccc2c(Br)cccc2c1)C(=O)O +CC(CCCN1CCCS1(=O)=O)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +CCCCn1ncc(C(=O)O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccsc2)nc1 +CC(C)CC(CC(=O)NO)C(=O)NC(Cc1ccncc1)C(=O)NC(C)c1ccccc1 +N#Cc1ccc(-c2nc3c(NC4CCCC4)cccn3c2-c2ccnc(NC3CCCC3)n2)cc1 +CC(=O)Nc1nc(C)c(-c2ccc(S(C)(=O)=O)c(Br)c2)s1 +Cc1ccccc1S(=O)(=O)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)CC2(C)C1 +CC(NC(=O)N1CCc2cccnc2C1c1ccc(C(F)(F)F)cc1)C(F)(F)F +Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(C)C)cc2)no1 +CCCCCNc1nc(SCc2ccc([N+](=O)[O-])cc2)c2ncn(C3OC(CO)C(O)C3O)c2n1 +O=C(CCCCN1CCN(Cc2ccccc2)CC1)n1c2ccccc2c2ccccc21 +O=C(C1CC1)N(Cc1cccnc1)c1cc(F)cc(-c2nc3ccccc3s2)c1 +CC(=O)Nc1cc(-c2c(Nc3cc[nH]n3)nc3cccnn23)nc(C)n1 +CCc1ccc(Cn2cccc(C=CC(=O)NO)c2=O)cc1 +COC(=O)C1CC(c2cnc(N)c(-c3ccc(C(=O)NC(CO)c4cccc(Cl)c4)c(F)c3)c2)CN1 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+Nc1ncc(-c2cc(N3CCN4CCCC4C3)nc(N3CCC(F)(F)C3)n2)cc1OC(F)F +N#Cc1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)cc(C(F)(F)F)c1 +COC(=O)CCC(C)=CCc1c(O)c2c(c(C)c1OC)COC2=O +Cn1cncc1CNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1 +Nc1cc(-c2cc(C(F)(F)F)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2Cl)ccn1 +CCNC(=O)C1OC(n2cnc3c(N)nc(C#Cc4nccs4)nc32)C(O)C1O +Cc1nc(C(=O)O)cc(-c2ccc(Cl)c(Cl)c2)n1 +CCCCCCCCc1ccc(-c2oc3cc(O)cc(O)c3c(=O)c2O)cc1 +O=C(CCCCn1c(=O)c2ccccc2n(Cc2ccccc2)c1=O)NC1CCN(Cc2ccccc2)CC1 +COC1CC(NC(=O)C2CC(OC3OC(CN)C(O)C(O)C3N)C(N)CC2N)C(N)CC1N +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3ccc(OC(F)(F)F)cc3)c(F)c2)CC1 +O=C(NCCS(=O)(=O)c1ccc(C(F)(F)F)cn1)c1cnc2ccccc2c1 +Nc1ccc(-c2ccc(Oc3cncc4sc(-c5nn[nH]n5)cc34)cc2)cc1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc4cc(OCC(=O)N5CCOCC5)ccc4n3)C12 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ncncc2[nH]1)C(F)(F)F +O=C(c1cc(Oc2ccccc2)ccn1)N1CCCN(C2CCC2)CC1 +CC(C)(C)c1ccc(-c2nc3c(N4CCN(Cc5ccc6ncccc6c5)CC4)cccc3[nH]2)cc1 +CC(C)(C)OC(=O)NN(CC1CCCCC1)c1nc(C#N)ncc1Br +CC(=O)N1CCC(c2cc(C#N)cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)c2Cl)CC1 +Cc1cc(C2CCN(C(=O)NC3CCCCC3)CC2)n(-c2ccc(S(N)(=O)=O)cc2)n1 +CCOC(=O)NC(CC(=O)N1CCN(C(C#N)c2cccnc2C)CC1)c1ccccc1 +CC(C)(C)CC(N)C(=O)N1CCN(CCCOc2ccc(C(=O)C3CC3)cc2)CC1 +Cc1cc(C)c(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCC1CCCO1 +N#Cc1ccc(-c2cc(Cl)ccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)nc1 +CCc1ncc(Cc2ccc3cccc(NC(C)=O)c3n2)c2cc(OC)c(OC)cc12 +CCC(Cc1ccc(O)cc1)NCC(O)c1cc(O)cc(O)c1 +Cc1cc(C)c(C)c(S(=O)(=O)N2CCc3ccccc32)c1C +COc1ncc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccccc1 +O=C(c1ccc(Cl)c(Cl)c1)N1CCC(CNCc2cccc(-c3cnco3)n2)CC1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(Cc4cc(C)no4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(=O)c3ccncc3)oc12 +O=C(O)CCCSCCN1C(=O)CCC1C=CC(O)Cc1cccc(OCc2ccncc2)c1 +Cc1nc(NCCCCNc2ccnc3cc(Cl)ccc23)nc(-c2ccccc2)c1C(=O)OC(C)C +O=C(Cc1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1)NCc1ccccc1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(c1ccc(Cl)c(F)c1)C1CCCN1 +COc1ccc2c(c1)c(CC(=O)NCCCCCCO)c(C)n2C(=O)c1ccc(Cl)cc1 +CCCNC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc21 +CN(c1ccc(Cl)cc1)c1ccc(C(=O)c2ccc(C(=O)C(C)(C)C)c(C(=O)O)c2)nc1 +Cc1cc(N)nc(CCc2cc(F)cc(CCCN(C)C)c2)c1 +Fc1ccc(N(CCCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C2CCNCC2)cc1 +CCC(O)(c1ncc(-c2cc(C)cc(Nc3cc(C(F)(F)F)ccn3)n2)s1)C1CCC(C(=O)O)CC1 +COc1cccc(F)c1CN1CC(C)CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nsnc5c4)c3c2)C1 +N#CC1CCN(c2nccnc2C2CN(c3ncc4ccccc4n3)C2)CC1 +O=S1(=O)N(Cc2ccc(CO)cc2)C(COc2ccccc2)C(O)C(O)C(COc2ccccc2)N1Cc1ccc(CO)cc1 +O=C(Nc1ccc(F)c(-c2nc3ccccc3o2)c1)c1cnccc1Cl +N=C(N)c1ccc(CC(=O)CCC(=O)NC(CC(=O)O)C(=O)NC(Cc2ccccc2)C(=O)O)cc1 +CS(=O)(=O)c1ccc(N2C(=O)OC(=Cc3ccc(O)c(Br)c3)C2=O)cc1 +Cn1cc(-c2ccc3c(c2)[nH]c2c(C(N)=O)cnc(NC(C4CC4)C(F)(F)F)c23)cn1 +CC1CCCN1CCc1ccc(-c2ccc(CC(=O)O)cc2)cc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cnn(-c2ccc(OC(F)(F)F)cc2)n1 +O=C(Nc1ccc(-c2ccc3cn[nH]c3c2)cc1)Nc1cccc(F)c1 +COC(=O)c1c(Cl)cccc1-c1ccc(C(C)NC(=O)C2(NC(=O)c3ccno3)COC2)c(F)c1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)NCc2ccccn2)c1=O)C(=O)C(F)(F)F +O=C(Nc1ccc(F)cn1)c1cc(Oc2cncc(F)c2)cn2cnnc12 +NS(=O)(=O)c1ccc(CCNC(=O)CNCCNCC(=O)O)cc1 +Cc1cc(N)nc(C)c1CNC(=O)Cc1c(Cl)ccc(NCC(F)(F)c2ccccc2)c1F +CN(c1ncnc2[nH]ccc12)C1CCC(CS(=O)(=O)N2CCC(NC(=O)OC(C)(C)C)C2)CC1 +CN(Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)COc1ccc(Cl)cc1)CC2)c1ccc(C(F)(F)F)cc1 +CC(C)CC(C(=O)NO)N1CCC(N)(c2ccc(OCc3cc(C(F)(F)F)nc4ccccc34)cc2)C1=O +Cc1cc(C2(c3cccc(-c4cncnc4)c3)N=C(N)N(C)C2=O)c(Cl)s1 +CCCCC(C(=O)N1CCCC1C(=O)Nc1ccc(Cl)c(Cl)c1)C(F)C(=O)NO +N=C(N)c1cccc(NC(=O)Nc2cccc(S(=O)(=O)NCc3ccc(S(N)(=O)=O)cc3)c2)c1 +CC(C)Oc1cc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)cc(OC(C)C)c1 +NC1(c2ccc(-c3ncc4cccnc4c3-c3ccccc3)cc2)CCC1 +CC(c1ccc(Br)cc1)n1c(CC(C)(C)C(=O)O)nc2cc(OCc3ccc4ccccc4n3)ccc21 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1 +COCCN(C)C(=O)c1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1F +Brc1ccc2c(c1)ncc1nc(-c3ccccc3Br)[nH]c12 +O=C1NCN(c2ccccc2)C12CCN(CCCOc1ccc(F)cc1)CC2 +N#Cc1cnc2c(Cl)cc(NCc3c[nH]nn3)cc2c1Nc1ccc(F)c(Cl)c1 +COC1CCC(CC(=O)NC2CCC(CCN3CCN(c4cccc5c4OCO5)CC3)CC2)C1 +O=C(c1cc(C2CC2)c(O)cc1O)N1Cc2ccccc2C1 +Cc1cc(C=NNc2nc(N)ncc2[N+](=O)[O-])c(C)n1-c1ccccc1F +Cn1nccc1-c1ccc(I)cc1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1C#N +CC(Nc1nc(N)nc(N)c1C#N)c1nc2c(F)ccc(Br)c2c(=O)n1-c1cncc(F)c1 +O=C(O)c1cc2c(s1)-c1ccc(Cl)c(Cl)c1CC2 +CC(=O)Nc1cc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)ccn1 +CC(Nc1nc(N)nc(N2CCC(CC(N)C(=O)O)CC2)n1)c1ccc2ccccc2c1 +CCOc1ccc(-c2nc(C#N)nc3c2ccn3CC(=O)N2CCN(C)CC2)cc1C(F)(F)F +COc1cccc(N2C(=O)N(Cc3ccccc3F)C3(CCN(Cc4ccc(-c5ccncc5)cc4)CC3)C2=O)c1 +CCN(CC)CC(c1ccccc1Cl)N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)CC2NCCc3ccccc32)CC1 +CC(c1ccccc1)N(CC#Cc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21)C(=O)C(C)(C)C +O=C(Nc1ccc(OCCc2ccsc2)cc1C(=O)O)c1ccc(Cl)cc1Cl +CCCc1cc(=O)n2nc(NCc3ccc(Cl)cc3OC)c(C#N)c2[nH]1 +CCN(CC)C(=O)C1Sc2cc(OCCF)ccc2-c2c1c1ccccc1n2C +CCOC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +CCc1nc(N)nc(N)c1C#CC(C)c1cc(OC)cc(-c2cccc3cnccc23)c1 +O=C1NC(=O)C(Cc2ccc(N3CCC(NCC(O)c4ccc(O)c(NS(=O)(=O)c5ccccc5)c4)CC3)cc2)S1 +COc1nc(Nc2ccc(C#N)cc2)nc(Nc2c(Br)cc(C)cc2Br)n1 +O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(c1ccc(F)cc1)c1ccccc1[S+]2[O-] +CCOC(=O)CSC1=C(C#N)C(c2ccc(C)o2)CC(=O)N1 +Cc1cc(CN(C)C)ccc1C(=O)Cn1ncc(OCc2ccc(Cl)cn2)cc1=O +Cc1nc(C(F)(F)F)c(-c2cc(C(=O)N3CC(F)(c4ccc(C#N)cc4)C3)c(C)cc2C)[nH]1 +Cc1ccc2c(-c3nnc(SCCCN4CCc5cc6c(cc5CC4)OCC(=O)N6)n3C)cccc2n1 +CC(C)=CCOc1cc(Oc2ccc(S(=O)(=O)N3CC4CCC(C3)O4)cc2)cc(C(=O)Nc2cc(C)n(C)n2)c1 +CS(=O)(=O)Oc1ccc2c(c1)OS(=O)(=O)C=C2 +Fc1ccc(-c2[nH]c(SCCc3ccccc3)nc2-c2ccncc2)cc1 +COc1ccccc1-c1ccc(C(N)=O)c2[nH]c3cc(C(=O)N4CCN(C)CC4)ccc3c12 +COc1ccc2c3c4c(c5c(ccc6ccn(C)c65)c3n(CCCN3CCN(C)CC3)c2c1)C(=O)NC4=O +CC(C)c1n[nH]cc1-c1ccnc(Nc2ccc(N3CCNCC3)cn2)n1 +Cc1cc2c(OCC(O)CN3CCC(c4cccc5ccsc45)CC3C)cccc2[nH]1 +O=C(CCc1ccc(C(=O)NCC(NS(=O)(=O)c2cccc3cccnc23)C(=O)O)s1)NC1=NCCCN1 +Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc(OC(F)(F)F)cc1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OCc3ccccc3)cc2n1Cc1ccccc1 +C=CCN1CCN(C(c2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)CC1 +COCCOc1c(OC)cc(Cc2cnc(N)nc2N)cc1OC +CCn1c(-c2nonc2N)nc2cncc(CN3CCC(N)CC3)c21 +CCC1C(C)C(Nc2ccccc2)c2ccccc2N1C(=O)c1ccc(Br)cc1 +COc1ccc(Nc2nc3ccccc3cc2-c2nc(C)nc(N)n2)cn1 +N#Cc1cccc(CC2(c3cccc(OC(F)(F)F)c3)CN(CC(O)C(F)(F)F)c3ccccc32)c1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc(Cl)ccc1Cl)C(F)(F)F +Cc1noc(C)c1Cn1cc(N2C(=O)CN(Cc3ccc(F)cc3)C2=O)cn1 +C1=C(c2cccnc2Oc2ccc(Nc3nc4ccccc4s3)cc2)CCNC1 +Cc1cc(C#N)cc(C)c1Oc1cc(Cl)nc(NC2CCN(Cc3ccncc3)CC2)c1 +Cc1noc(C)c1-c1ccc(F)c(COc2ccc(CCC(=O)O)c(F)c2)c1 +CCN(CC)CCOc1ccc(Cn2c3ccccc3c3sc4cc(O)ccc4c32)cc1 +CCCc1nc2ccc(C(=O)NC(CC)c3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(C=Cc1ccc(CNC23CC4CC(CC(C4)C2)C3)cc1)NO +Nc1ccc(S(=O)(=O)c2cnc(-c3ccc(S(N)(=O)=O)cc3Cl)s2)cn1 +COc1cccc(Nc2c(C(N)=O)cnc3ccc(S(=O)(=O)c4ccc(-c5ccoc5)cc4)cc23)c1 +Cc1cccc(C#CC2(O)CC3CCC(C2)N3C(=O)N2CCC2)c1 +COc1cnc(C(=O)Nc2cc(F)c(F)c(C3(CF)N=C(N)OC4CC43)c2)cn1 +CCC(CO)Nc1nc(-c2ccc(C(C)(C)O)nc2)cc2ncn(C)c(=O)c12 +Cc1cc(C)cc(C(=O)C2(NC(=O)c3ccc4c(c3C)CCCO4)CCCCC2)c1 +CCCS(=O)(=O)c1ccnc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)c1 +O=C(NO)c1ccc(-c2ccc(CNCc3ccc4c(c3)OCO4)cn2)s1 +COC12C(COC(N)=O)C3=C(C(=O)C(CSc4nccn4C)=C(N)C3=O)N1CC1NC12 +CC(C)c1ccccc1N1CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)CC1=O +COc1cc(C=CC(=O)c2cc(OC)c(OC)c(OC)c2)ccc1B(O)O +Cn1c(-c2ccc(N3CCNCC3)cc2)c(-c2ccc(CO)cc2)c2c(Cl)ccnc21 +COc1ccc2[nH]c3c(c2c1)C1(c2cccc(O)c2)CCN(C)C(C3)C1 +CC(CCC(=O)NCCC(=O)Nc1nnc(S(N)(=O)=O)s1)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CCC12C +CNC(=O)c1nn(C)cc1NC(=O)c1nc(C(C)C)ncc1Nc1cncnc1 +CN(C)c1ccc(-c2nc3ccc(NC(=O)c4ccccc4)cc3o2)cc1 +CCCNC(=O)Nc1cccc(-c2ccc(CC(NS(=O)(=O)c3ccc(OC)c(OC)c3)C(=O)O)cc2)c1 +O=C(O)c1ccc(C(=O)Nc2cc(C3CC3)[nH]n2)cc1 +CC(=NOCCO)c1ccc2nnc(Cc3cc4cccnc4cc3F)n2n1 +CC(NC(=O)c1cnco1)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 +COc1cnc(-c2ccc(NC(=O)Nc3cccc(C(N)=O)c3)cc2)nc1N1CCOCC1 +Cc1ccc2oc3c(=O)[nH]c(-c4ccccc4Cl)nc3c2c1 +CC1COc2ccc(Br)cc2C(C)N1C(=O)c1ccc(Cl)cc1 +CCCCc1nc2ccn(Cc3ccccc3Cl)c(=O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCOCCn1c(=O)c(NCCCO)nc2cnc(-c3ccc(OC)nc3)cc21 +CC(C)C(NC(=O)c1ccc(Cl)cc1)C(=O)N1CCC(N)(c2ccc(Cl)cc2)C(C)(C)C1 +Cc1[nH]nc(N)c1-c1nc2c(F)cc(S(N)(=O)=O)cc2s1 +Cc1c(CNC2CCC(F)C2)nn(CCC#N)c1-c1cc(F)cc(F)c1 +COc1ccc(Cc2nc3c(o2)CCc2cc(-c4ccnc(C)c4)ccc2C3=O)cc1 +CC(C)(C)C(=O)OCC1(CO)CC(=Cc2ccc(F)c(Cl)c2)C(=O)O1 +CNC(=O)Oc1ccc2c(c1)C1(C)CCN(C)OC1N2C +c1cc(C2=NCCN2)ccc1NCCCCCNc1ccc(C2=NCCN2)cc1 +CCOc1cc(-c2cccc(F)c2)cnc1Nc1cccc(C)n1 +CNCc1ccc(-c2cncc(CCc3cc(C)cc(N)n3)c2)cc1 +Cc1c(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)ccc2c1COC2=O +Cc1cc(Cl)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CC1(C)CC(N)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3ccc(O)cc3F)n2)C1 +O=C(NCc1ccc(Cl)cc1)c1cn2c(C(O)CO)cc3cc(CN4CCOCC4)cc(c1=O)c32 +CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2c(O)ccc[n+]2[O-])cc1 +Cc1cccc(-c2cc(Nc3nn(C)cc3C(F)(F)F)nc3[nH]cc(C#N)c23)n1 +COc1ccc(C2CN(C)Cc3cc(OCCCN4CCC(F)(F)C4)ccc32)cc1 +CC1(C(=O)O)CCc2ccc(OCCCOc3ccc(C4CCC5(CC4)CC5)cc3Cl)cc2O1 +COc1cccc(C(=O)NCCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1 +O=C(Nc1ccc(Cl)cc1)C1CN(Cc2ccncc2)CC1C(=O)Nc1ccc(-n2ccccc2=O)cc1F +COc1cc2ncnc(Nc3ccccc3F)c2cc1OCCCCC(=O)NO +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(C4CCN(C(=O)OC(C)(C)C)C4)C3)cc12 +COc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)cc2)cc1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccccc1-c1ccccc1F +O=S(=O)(Nc1cc(-c2ccc3nccc(N4CCN(Cc5ccncc5)CC4)c3c2)cnc1Cl)c1ccc(F)cc1 +CC(C)Cc1ccc(CN2CCCC(NC(=O)c3cnc4ccccn4c3=O)C2)cc1 +CCc1cc(OCC2=C(c3cccc(-n4ncc(C(=O)O)c4C)n3)CCCC2C)ccc1C1CCN(C(=O)C2CC2)CC1 +O=C1NC(=S)SC1=Cc1csc(-c2ccc(OC(F)(F)F)cc2)n1 +CCC(CC)c1nnc(-c2nc(-c3ccc(Cl)cc3Cl)n(-c3ccc(Cl)cc3)c2C)o1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CC(=O)Nc5ccccc54)ncc23)ccn1 +Cc1nc2ccc(CNc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 +COC(=O)c1ccc(CCCCN=C(N)NC(=O)c2nc(Cl)c(N)nc2N)cc1 +Cc1cc(C)cc(C(=O)Nc2ccc(Cl)c(C(=O)Nc3cncs3)c2)c1 +COc1ccc(CC(NC(=O)C(NC(=O)C(Cc2ccc(OC)cc2)NC(=O)c2ccc(Cl)cn2)C(C)C)B(O)O)cc1 +C=C(c1ccccc1OCC(O)CNC(C)(C)C)n1cnc2ccccc21 +CC1CC(=O)N(C2CCN(C3CCCCCCC3)CC2)c2ccccc21 +Cc1cc(=O)n(-c2ccc(Br)cc2F)nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 +CC(=O)N1CCC2(CCC(Nc3nc(Nc4cnn(C)c4)ncc3Cl)CC2)CC1 +COC(=O)C1CCCCC1c1nc(C2CCCCN2C(=O)COc2ccccc2)no1 +COc1cc2ncnc(Nc3ccc(NC(=O)Nc4cccc(Br)c4)cc3)c2cc1OC +CC(C)(C)c1cn(CC2CCCO2)c(=NC(=O)c2cc(C(F)(F)F)ccc2OCc2ccccc2)s1 +Cc1cc(-n2cnc3c(NCC4CCOCC4)cc(Oc4ccc(Cl)c(F)c4)cc32)ccc1C(=O)NC1CC1 +O=C(COc1ccc(C(=O)NO)cc1)Nc1ccc2ccnc(Nc3ccc4ccccc4c3)c2c1 +CC(=O)N1CCN(Cc2ccnc(Nc3ncc(C#N)s3)c2)CC1 +CN1C(=O)CC(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c3ncccc23)N(C)C1=O +CNCc1cc(-c2cccnc2F)n(S(=O)(=O)c2cccc(C#N)c2)c1 +O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2nc(-c3ccc(Cl)cc3)cs2)C2C=CC1C21CC1 +CC(C)(C)NC(=O)C1CC2CCCCC2CN1CC(O)C(Cc1ccccc1)NC(=O)C1CCCS(=O)(=O)C1 +Cc1ccc(-c2cccc(C3OC(CO)C(O)C(O)C3O)c2)cc1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C1CCCN1 +CCCCc1nc2[nH]cnc2c2nc(-c3ccc(OCC)cc3)nn12 +CCCC(CCC)(CNC(=O)C1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 +[H]C(=NN1CC(=O)NC1=O)c1ccc(-c2ccc(N=[N+]=[N-])cc2)o1 +NC1CCCCC1Nc1cccc2nc(-c3c(NC4CCCNC4)nc(N4CCOCC4)[nH]c3=O)sc12 +N#Cc1cc(NCc2cc(F)c(F)cc2-c2ccc(C(=O)NCCC(=O)O)nc2)ccc1-c1ccc(Cl)cc1F +COc1cc(C(=O)OCCCN2CCCN(CCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2)cc(OC)c1OC +CCN(CC)C(=O)C1CCCc2c1c1c(OC)cccc1n2CCF +CC(C(N)=O)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +N#CCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN(C)C(=O)c2ccccc2)c1C +Cc1cc(C)c(Oc2ccc([N+](=O)[O-])c(NC3CCN(Cc4ccc(S(N)(=O)=O)cc4)CC3)c2)c(C)c1 +CCOC(=O)C=CC(=O)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +O=C(CSc1ccc(C(=O)Nc2ccc(F)cc2)cn1)OCc1ccc(Br)cc1 +CN(C)CC(=O)NC1CCC(Nc2nc(Cl)cc(-c3c[nH]c4ncccc34)n2)CC1 +COC1CN(c2nc(-c3cc(C)ccc3OCc3ccc4c(c3C)CCN(CC3CCOC3)C4)cs2)CCC1C(=O)O +CN(C)C1CCN(c2cc(NCC(C)(C)C)ncn2)C1 +COc1ccc(C=C2SC(=Nc3nsc4ccccc34)NC2=O)cc1 +CN(C)CCOc1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +CCC1(c2ccc(CSc3ccc(F)cc3)cc2)Oc2ccccc2-n2cccc2C1=O +Clc1ccc(N2CC3CC2CN3Cc2c[nH]c3ncccc23)cc1 +CC(C)n1c(Nc2cccnc2)nc2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21 +CCCn1ncn(-c2ccc(N3CCN(c4ccc(OCC5COC(C)(c6ccc(Cl)cc6Cl)O5)cc4)CC3)cc2)c1=O +O=C(N1CCOCC1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 +CC1COC(c2cccc(OC(=O)NC3CCCCC3)c2)=N1 +O=C(O)c1ccc(C(=O)Nc2ccc(S(=O)(=O)Nc3cccc(B(O)O)c3)cc2)cc1 +CC(C)c1ccc(NC(=O)Oc2ccc3c(c2)C2(C)CCN(CCc4ccc(F)cc4)C2N3C)cc1 +O=C1NC(=O)c2cccc(NC(=O)c3ccc([N+](=O)[O-])cc3)c2C1=O +C#Cc1nc(NC)c2ncn(C3CC(OP(=O)(O)O)C4(COP(=O)(O)O)CC34)c2n1 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC2C(=O)Nc3ccc(Cl)cc3C2C1 +O=c1c(-c2ccc(F)cc2)c(-c2ccnc(Oc3ccccc3)n2)n2n1CC(N1CCCCC1)C2 +CCC(=O)N(c1ccccc1)C1CCN(CCc2ccc(N=C=S)cc2)CC1C +O=C(O)c1cccc(-c2cnc(C(=O)C3Cc4ccc(Oc5ccccc5)cc4C3)o2)n1 +CCc1nc2ccc(C3CCN(CC(=O)N4CCCC4)CC3)cn2c1N(C)c1nc(-c2ccc(F)cc2)cs1 +CS(=O)(=O)c1cccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)c1 +CN1CCN(Cc2ccc3c(c2)-c2n[nH]c(-c4ccc(CN(C)C(=O)Nc5ccc(Cl)c(Cl)c5)s4)c2C3)CC1 +Nc1ncc(Cc2ccc(OCc3ccccc3)cc2)c(N)n1 +CCCCN(Cc1ccc(CCCN2C(=O)CCC2=O)c(OC)c1)C(CC(=O)O)c1ccc(Cl)cc1 +CC(F)(F)c1nn2cc(-c3cc4cc(Cl)ccc4o3)nc2s1 +c1ccc(C2CCc3cc(Oc4ncc(CNCc5cccnc5N5CCOCC5)s4)ccc3O2)cc1 +c1ccc(-c2csc3nc(NCCN4CCCC4)nc(N4CCC(CNC5CCC5)CC4)c23)cc1 +OCc1nccc(N2CCN(c3ncnc4ccccc34)CC2)n1 +COc1cccc(C2CC(=O)C(=C(C)Nc3ccccc3C)C(=O)C2)c1 +O=C(NCCN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccncc1 +CCN1CCN(c2cc3[nH]c(SC4(C)CCC(NS(C)(=O)=O)CC4)nc3cc2Cl)CC1 +COC12CCC3(CC1COCc1cccc(Cl)c1)C1Cc4ccc(O)c5c4C3(CC[N+]1(C)CC1CC1)C2O5 +CC(=O)OCC1OC(NC(=O)NCCCc2ccc(N(CCCl)CCCl)cc2)C(F)C(OC(C)=O)C1OC(C)=O +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C(=S)NC(=O)c4ccccc4Cl)CC3)cc21 +O=C(N=C1SCC(=O)N1c1ccccc1Cl)c1ccccc1 +CCCN1C(=O)C(NC(=O)Nc2ccc(N3CCN(c4ccncc4)CC3)cc2)N=C(C2CCCCC2)c2ccccc21 +Cc1nc2cc(-n3ncc(C(=O)c4cc5cc(SC(F)(F)F)ccc5[nH]4)c3N)ccc2[nH]1 +CC(=O)C(=[N+]=[N-])C(=O)N(c1ccccc1)C1CCN(CCc2ccccc2)CC1C +CCC=CC(CC)CC(=CC1(CC)CC(CC)C(CC(=O)O)OO1)CC +CN(CCCCCCC(=O)NO)C(=O)c1cccc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)c1 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+O=C(c1cccc(O)c1)c1ccc(-c2cccc(NS(=O)(=O)c3ccccc3[N+](=O)[O-])c2)s1 +O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(OC(F)(F)F)cc3)c(Cl)c2)cn1 +N#Cc1cc(S(=O)(=O)c2cccc(Cl)c2)cc2c3c(oc12)CCNC3 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(OC4CCC4)cc3)C2)cc1 +O=C(C1CC1c1ccccc1)N1CCC(N2CCCCC2)CC1 +Cc1cc(Oc2ncccc2Br)ccc1-c1c(C)n[nH]c(=O)c1C +CCc1c(C)c2c(c(O)c1CC=C(C)CCC(=O)O)C(=O)OC2 +O=c1cc(OCc2ccc(F)cn2)ccn1-c1ccc2c3c([nH]c2c1)CC1CCC3N1 +Cc1c(-c2ccccc2)oc2c(C(=O)NCCCN3CCN(c4ccccc4OCCCO[N+](=O)[O-])CC3)cccc2c1=O +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1cccc(N=[N+]=[N-])c1 +COc1ccccc1CC(=O)Nc1nc(N)nc(-c2ccco2)c1[N+](=O)[O-] +COc1ccc(C2C(c3ccccc3)C(=O)N2c2ccc(S(N)(=O)=O)cc2)c(OC)c1OC +Cc1nc2cccc(-c3cc(C(N)=O)n[nH]3)c2nc1NC(C)(C)C +CCc1cc2c(cc1Cn1c(C(=O)O)c(Cc3cccc(C(=O)O)c3)c(=O)c3cc(OCC(C)C)ccc31)OCO2 +CCN(CC)C(=O)C1Sc2cc(O)ccc2-c2c1c1ccccc1n2CCF +CCNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3sccc3n2)cc1 +Cc1cnc(Cl)nc1-c1ccc(N(Cc2cccc(OCCCCN3CCOCC3)c2)C(=O)c2ccc(O)cc2O)cc1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCN(C(=O)CC)CC4)cc3OC)ncc2C(F)(F)F)c1 +CCCCCCC1CCc2cc(C3CCC(N)(COP(=O)(O)O)C3)ccc2C1 +Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)CC2)c2cc(Cl)ccc12 +CS(=O)(=O)c1ccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)cc1 +COCC(C)n1c(=O)c(C)nc2c(-c3ccc(Cl)cc3Cl)ccnc21 +O=C(C=Cc1cccc2[nH]cc(Cc3ccc4ccccc4c3)c12)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +O=C(NCCCN1CCC(Cc2ccc(F)cc2)CC1)Nc1ccccc1C(F)(F)F +CC(=O)N1CCN(c2ccc(CN3CCCN(c4ccccc4)S3(=O)=O)c(F)c2)CC1 +COc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1cccnc1)CC2 +CC1CCC(Cn2c(N3CCCC3c3nccs3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +O=C(Nc1ccccc1)N1CCN(Cc2csc3ccccc23)CC1 +Cc1ccc(O)cc1Nc1cc(N2CCOCC2)nc(-n2cnc3ccccc32)n1 +CSC1(CO)C(=O)N2c3c(O)cccc3CC2(SC)C(=O)N1C +COc1ccccc1COCCCOc1ccc(N2C(=O)CNCC2COc2ccc3c(c2)N(CCN(C)C(C)=O)CCC3)cc1 +O=C(NCc1cccnc1)C1=C(O)CCn2c1nc1ccccc12 +CCN1C(=O)COc2ccc(CC3CCN(CCOc4cccc5nc(C)ccc45)CC3)cc21 +O=C(O)CCc1ccc(-c2cc(F)c3cnn(-c4ccccn4)c3c2)cc1 +N#CCNC(=O)C(Cc1cccc(Cl)c1)NC(=O)C1=CCCCC1 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+C#CCn1c(=O)c2c(-c3cc(C#N)cn3C)n(Cc3ccnc4ccc(Cl)cc34)nc2n(CC2CC2)c1=O +Cc1nsc(-c2ccc(N3CCN(c4cc(Cl)cc(Cl)c4)CC3)nn2)n1 +CCCC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1CC +CCc1nn(Cc2ccc(-c3nc4c(F)c(F)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4cccc(OC(F)(F)F)c4)nc23)N1 +CNCCCCNCCCCNCc1ccc(CNCCCCNCCCCNC)c2ccccc12 +NC(=O)COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O +CN(CCO)Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 +Cc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)NS(=O)(=O)C1CC1)n2Cc1cc(C#N)ccc1F +O=C(O)C1CCCN1C(=O)c1cccc(COc2ccc(-c3cc(F)c(F)c4c3OCC=C4)cc2)c1 +COc1cccc2c(CC3NC(=S)N(C)C3=O)c[nH]c12 +Cc1ccc(Oc2ccc(N(CC(O)C(=O)NO)S(=O)(=O)Cc3ccncc3)cc2)cc1 +CC12CCC3c4ccc(O)cc4CC(CCCCc4cn(CC5COc6ccccc6O5)nn4)C3C1CCC2O +Cc1c(C(C)c2c(F)cccc2F)nc(N2CCSCC2)[nH]c1=O +CC(Nc1ncnc(N)c1-c1ccc(N)nc1)c1nn2cccc2c(=O)n1-c1ccccc1 +COc1ccccc1COCCCOc1ccc(C2=C(C(=O)N(C)Cc3ccccc3)C3CN(C(C)=O)CC(C2)N3)cc1 +FC(F)(F)Oc1cccc(Nc2nc3cc(-c4nnn[nH]4)ccc3c3sccc23)c1 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+COc1c(OCC(O)CN2CCOCC2)ccc2c1N=C(NC(=O)c1cncs1)N1CCN=C21 +Clc1ccccc1CN1CCCC(Nc2ccc3[nH]ncc3c2)C1 +N=C(N)c1ccc(OCc2cc(COc3ccc(C(=N)N)cc3)cc(COc3ccc(C(=N)N)cc3)c2)cc1 +COC(=O)c1ccc(Nc2nnc(SCc3ccc(F)c(F)c3)[nH]2)cc1 +CCC(=O)N1CCC(c2ccccc2)(c2nccn2Cc2ccccc2)CC1 +COC(=O)c1ccc(-c2nc3cccnc3n2C2CCCC2)cc1 +COc1cc(Nc2ncc3ccn(-c4cccc(C(=O)NCCN(C)C)n4)c3n2)cc(OC)c1OC +COc1ccccc1Nc1cc[nH]c(=O)c1-c1nc2c(C(C)C)ccc(C)c2[nH]1 +O=C(c1ccc(Cl)c(C(F)(F)F)c1)N1CCCC(c2ccccc2)=N1 +Cn1ncc2cc(Nc3ncc(C4CC4)c(NCCCNC(=O)C4CCC4)n3)ccc21 +N#CC1CCCN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)C1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(C(=O)N(C)C)CC2)CC1OC +CC(C)(C)n1nnnc1C(NCCCNc1ccnc2cc(Cl)ccc12)c1cccc2ccccc12 +c1cc(N2CCCNCC2)nc(-n2ncc3cnc(-c4cnn(C5CC5)c4)cc32)c1 +COC1CCN(c2cnc(C(=O)Nc3csc(-c4nncn4C4CC4)n3)cc2-n2cnc(C3CC3)c2)CC1 +Cc1ccccc1Cn1nc2c3ccccc3n(Cc3ccccc3)cc-2c1=O +CN(NC(=O)CC(=O)NN(C)C(=S)c1ccncc1)C(=S)c1ccncc1 +CNc1cccc(-c2cc(=O)c3cc(N4CCCC4)ccc3[nH]2)c1 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+O=C(Nc1ccccc1)c1c(NO)cc(-c2ccccc2)oc1=O +COc1cc(-c2cnc(C)n2C)ccc1Nc1cc2cc(-c3cn(C)nc3C)ccc2cn1 +CCCCCn1nc(C(=O)NN2CCCCC2)c(C)c1-c1ccccc1 +CCC(C)Sc1nc(C(CC)c2c(F)cccc2F)c(C)c(=O)[nH]1 +CONC(=O)CCn1c(=O)c(-c2ccc(OC)cc2)nc2ccc(NCc3cccc(C(F)(F)F)c3)nc21 +CS(=O)(=O)c1ccc(C(=O)N2CCOc3ccc(-c4ccc5nc[nH]c5c4)cc3C2)cc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCN(Cc3ccncc3)CC2)c2ccc(C)c(Cl)c2)CC1 +O=C1C(C(=O)N2CCCC2)CC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +CCCc1nc(CN2CCN(c3ccccn3)CC2)c(CO)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=CC(CC1CCNC1=O)NC(=O)C(CC1CCCCC1)NC(=O)OCCOCc1ccccc1 +O=C(Nc1ccc(Oc2ccccc2)cc1)Nc1ccc2c(cnn2CCN2CCC(F)(F)C2)c1 +COc1cccc(C(=O)N(C)c2nc(-c3cc(OC)c(OC)c(OC)c3)cs2)c1 +O=S(=O)(c1ccccc1)c1nc(NC2CCCCC2)c2ncn(C3OC(CO)C(O)C3O)c2n1 +CCCCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+]1(C)CCOCC1 +O=C(NCc1cccc(-c2cccc(-c3cc4c[nH]ccc-4n3)c2O)c1)Nc1ccc(F)cc1F +O=C(Nc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1)C1CCCCC1 +NC(=O)OC(CCN1CCN(c2ccccn2)CC1)c1ccccc1 +COc1ccc(-c2nc3c(NCCCNC(=O)C4CC4)c(Br)cnc3[nH]2)cc1 +CN(C)C(=O)c1cccc(Nc2nsnc2NC(c2ccccc2)C(F)(F)F)c1O +CCCOc1ccc(C(=O)NC2(C(=O)NC(Cc3ccccc3)C(=O)NCC3CCN(CC4CCOCC4)CC3)CCCC2)cc1 +COc1cc(C=C2CCCN3C2=NOCCC3c2cc(F)c(F)c(F)c2)ccc1-n1cnc(C)c1 +CC1(C)CCC(C)(C)c2cc3c(cc21)N=C(c1ccc(C(=O)O)cc1)c1cc([N+](=O)[O-])ccc1N3 +CC1(NC2=NCCNC(c3ccc(F)cc3)=C2)CCCCC1 +COc1cc(CN2CCN(CCCCCC(=O)N3Cc4cnn(C)c4Nc4ccccc43)CC2)cc(OC)c1 +Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccc2cc[nH]c2c1 +Cn1nccc1-c1ccc(Cl)cc1Oc1ccc(S(=O)(=O)Nc2nccs2)cc1C#N +O=C(O)CCn1cc(-c2cc(Cl)c3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +CN(C)CC(CN(C)C)c1cc2c3c(cccc3n1)C(=O)c1ccccc1-2 +CCCN(CC(=O)N1CCN(c2ccncc2)CC1)C(=O)c1nc2ccccc2n1Cc1ccccc1 +COC1CCN(c2nc(-c3c(C)cccc3C)nc3c2CN(c2cc(C(C)C)ccc2C)CC3)C(C)C1 +CN(CCON=C1c2sccc2-n2cccc21)Cc1ccccc1 +COCC(C)Nc1cncc(-c2cn(-c3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3C)nn2)c1 +Cn1nnnc1Cc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +CS(=O)(=O)NC1C2CCC(C2)C1CC=CCCCC(=O)O +CC(CO)Oc1ncccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +CC(CCCCc1ccccc1)C(O)C=CC1CC(F)(F)C(=O)N1CCCc1ccc(C(=O)O)s1 +C#CCCCCCNC(=O)c1coc(C2C3CCC(O3)C2Cc2ccccc2CCC(=O)O)n1 +CC(C)NC(=O)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)CCc1ccccn1 +NC(N)=NCCCC(N)C(=O)CC(Cc1ccccc1)C(=O)O +CCC(C)C(NC(=O)C(S)C(N)CCS(=O)(=O)O)C(N)=O +CN(C)CCOc1ccc2[nH]c(C(=O)N3CC(CCl)c4ccc(N)cc43)cc2c1 +COCCCS(=O)(=O)c1ncccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +c1cc2nc(c1)CNCCCN(Cc1ccc(CN3CCCNCc4cccc(n4)CNCCC3)cc1)CCCNC2 +O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC(c2ccccc2)(c2nccn2Cc2ccccc2)CC1 +C=CCNc1nc(N2CCC(NCC3c4ccccc4COc4ccccc43)CC2)c2ncn(CC=C)c2n1 +CN(C)C(=O)c1ccc(NCc2cncn2Cc2ccc(-c3ccccc3)cc2)cc1-c1ccccc1 +O=C(OCc1ccccc1)C(CCCCn1cnc2c1NC=NCC2O)(Cc1ccccc1C(F)(F)F)C(=O)OCc1ccccc1 +CC(C)C1=C(CCNC(=O)C2CC2)c2c(ccc3c2CCO3)C1 +CCCCOc1ccc(-c2ccc(C(=O)O)cc2F)cc1CNC(=O)c1ccc(C(F)(F)F)cc1 +CCc1nn(Cc2ccc(NC(=O)OCc3ccccc3Cl)cc2)c(CC)c1CC(=O)O +COc1cc2c(cc1C)CC1C2CCCN1C(=O)c1ccc2nc[nH]c2c1 +CCC(NC(=O)Nc1ccc(Cl)cc1)C(=O)Nc1ccc(N2CCOCC2=O)cc1 +Cc1nc(COc2ccc3c(c2)C(O)C(Cc2cccnc2)CO3)ccc1[N+](=O)[O-] +Nc1cc(NC2=NCC(O)CN2)cc(C(=O)NCC(=O)NC(CC(=O)O)c2cc(Cl)cc(I)c2O)c1 +O=C(c1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CCN(Cc1ccncc1)Cc1cccc(-c2ccc(CCNCCc3ccc(O)c4[nH]c(=O)sc34)cc2)c1 +CC(C)(O)c1ccc(Nc2nc3ccc(C#N)cc3[nH]2)cc1 +COc1ccc(CCCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 +NC(=O)n1cc(NC(=O)N2CC(F)CC2CNS(=O)(=O)c2cccc(Br)c2)c2ccccc21 +Fc1cnc(N2CCN(CCCCc3ccc(F)c4ccccc34)CC2)nc1 +COC1Cc2sc(-c3ccccc3)cc2C2(CCN(Cc3ccco3)CC2)O1 +Nc1nccc(-c2cc3c([nH]2)CC(C2CC2)NC3=O)n1 +COCCCOc1ccnc(C[S+]([O-])c2nc3ccccc3[nH]2)c1C +COc1ccc(-c2nc3cnc(NCc4ccc(F)c(Cl)c4)nc3n(CCNC(C)=O)c2=O)cc1 +O=c1cc(Cn2c(C3CCC3)nc3ccncc32)c2ccc(F)c(F)c2[nH]1 +CCn1c(=O)c(-c2ccc(F)c(NC(=O)Nc3cc(C(C)(C)C)no3)c2)cc2cnc(NC)cc21 +COC(=O)CC1c2ccccc2N=C(Nc2ccc(-c3ccccc3)cc2)N1CCCCCN +Cc1cc(Oc2ccc(-c3nc4cc(C(N)=O)ccc4[nH]3)cc2)ccc1F +Cc1nc(-c2ccc(Cl)cn2)nc(NCC(NCc2ccccc2)c2ccccc2)c1Cl +CC(C)(N)CNC(=O)CC1CCC2(CC1)OOC1(O2)C2CC3CC(C2)CC1C3 +Cc1cc(Oc2cc(NC(=O)C3CC3)ncn2)ccc1NC(=O)Nc1cc(OC(F)(F)F)ccc1F +O=C(O)c1nc2ccccc2n(C2CC3CCC(C2)N3C23CC4CC(CC(C4)C2)C3)c1=O +c1cncc(-c2ccc3c(c2)CCc2nnc(C4CC4)n2-3)c1 +NC1=NCC(Cc2ccc(-c3ccccc3)cc2)C(N)=N1 +CNC(=O)C1Cc2cc(-c3ccccc3)ccc2N1C(=O)COc1ccc(F)cc1 +COC(=O)c1cc(OC(=O)c2ccc(OC)c(O)c2)c(OC)cc1CCN(C)C +CCOC(=O)C1=CC2C(=O)c3cccnc3C(=O)C2C(c2ccc(Cl)cc2)=N1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)cc1C(C)(C)C +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2ccc(C)c3ccccc23)c(Cl)c1 +COc1ccc(-c2nn(C(C)(C)C)cc2CN2CCCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc1 +CC(Oc1cc(-c2ccc3ncn(C)c3c2)cc2ncccc12)C1CNC(=O)C1 +CN1CCC2(CCCCCc3ccccc3)c3cc(O)ccc3OC2C1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(F)cc4)cn3CCN3CCCC3)CC2)c1Br +CC(C)c1cccc(C(C)C)c1NC(=O)OCC(Nc1ccc(CN(C)C)cc1)c1ccccc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1nc(-c2ccc(Cl)c(OC(F)(F)F)c2)no1 +NS(=O)(=O)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 +CSc1c(Cl)nc(-c2ccc(NC(=O)Nc3ccc4oc(=O)[nH]c4c3)cc2)nc1N1CCOCC1 +N#Cc1ccccc1-c1ccc(C(=O)N(Cc2ccccc2)CC2CCCO2)cc1 +COc1ccccc1CNC1C2CC3CCOC(C2)N3C1C(c1ccccc1)c1ccccc1 +CCC(CC)N1C(=O)C(C)(CC2OC(=O)NC2=O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COc1c(C(=O)N2CCC(F)(CNCc3ccc(C)cn3)CC2)csc1Br +O=C(C(=O)C(Br)c1ccccc1)C(Br)c1ccccc1 +O=C(O)COc1cc(Cl)ccc1C(=O)NCc1c(Br)c(Br)c(Br)c(Br)c1Br +O=C(CN(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NO +COc1nc(Nc2c(C)cc(C)cc2C)nc(NC2CCN(Cc3ccc(C#N)cc3)CC2)n1 +CCc1ccc(Cc2cc3c(cc2Cl)OCCCCOCC2OC3C(O)C(O)C2O)cc1 +Cn1cc(Nc2ncc(C(F)(F)F)c(CCc3ccccc3C3(C(N)=O)CC3)n2)cn1 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3=CCC2(C)C1(O)C(=O)CO +Nc1c(Br)cc(C(=O)NC2CN3CCC2CC3)c2[nH]cnc12 +CON=C(CCN1CCN(c2ccccn2)CC1)c1cccc(C)c1 +NC(CC(=O)NC1(c2cccc(-c3cnc(C4CCCCN4)s3)c2)CCS(=O)(=O)CC1)Cc1ccccc1F +Cc1c(C(C)c2c(F)cccc2F)nc(SCc2ccc(C#N)cc2)[nH]c1=O +CCN(CC)C(=O)CN1CCCC(c2nc3ccccc3n2Cc2ccc(F)cc2)C1 +Cc1cc(OCCCc2c(C(=O)O)sc3cc(Cl)ccc23)cc(C)c1Cl +CS(=O)(=O)Nc1cc(C(O)CNC2CCN(c3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)CC2)ccc1O +O=C(Nc1ccc(-c2nnc(NCCCCN3CCCCC3)o2)cc1)c1ccccc1F +CCCCCCCCC=CCCCCCCCCCCC(=O)NCc1ccc(O)c(OC)c1 +O=C(CCCCn1cc(-c2ncnc3[nH]ccc23)cn1)NO +CSCC(NC(=O)c1ccc(C#Cc2ccccc2)cc1)C(=O)NO +COc1ccc(CC(O)c2cc(OC)c(OC)c(OC)c2)cc1O +COc1ccc(NC(=O)Nc2ccc(Oc3ncnc4ccn(C)c34)cc2Cl)cc1C(F)(F)F +CC(C)C(=O)Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CC1C2Cc3cc(Cl)c(O)c(Cl)c3C1(C)CCN2Cc1ccccc1 +NC(=O)c1cccc2c1C(=O)N(C1CCN(C(=O)C3CCCCC3)CC1)C2 +CC(C)(C(=O)OC1(C)C2CC3CC(C2)CC1C3)c1cccnc1 +O=C(C1CNCCC1(O)c1ccc(F)c(F)c1)N(Cc1cn(Cc2ccc(OC(F)F)cc2)c2cccc(F)c12)C1CC1 +CC(=O)Nc1ccc(-c2ccc(C3COC4(C=CC(=O)C=C4)O3)cc2)cc1 +Oc1ccc2nc(Cl)n(-c3ccccc3SC(F)(F)F)c2n1 +Nc1ccc(-c2ccsc2)cc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 +Cc1nc2cnccc2n1-c1ccc(-c2nc3ccccc3[nH]2)cc1 +N#Cc1c(-c2ccccc2)nc2[nH]nc(-c3ccccc3)c2c1C1CC1 +O=C(Nc1ccc(CC(NC(=O)C2CCC(=O)N2Cc2ccccc2)C(=O)O)cc1)c1ccccc1 +CONC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(CCS(=O)(=O)NC(C)=O)cc3)ncc2c1=O +CN(CC(=O)N1CCN(c2ccccc2)CC1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +COc1ccc(-c2nn(-c3ccccc3)cc2CN2CCCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc1 +COc1ccc(C(=O)c2c(C)n(Cc3cc(OC(C)C(=O)O)ccc3F)c3ncccc23)cc1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCC3)CC2)c1)c1ccc(Cl)cc1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(-c3nn[nH]n3)cnc3ccccc23)cc1 +O=C(O)CC1CCn2c1c(Sc1ccc(Cl)c(Cl)c1)c1c(CC3CC3)nccc12 +N#CC1CCCN1C(=O)c1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 +Fc1ccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1F +COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2nc3ccc(F)cn3c2C)cc1 +COC(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(N(CC(=O)N(C)C)C(C)=O)cc1)c1ccccc1 +CC(C)Cc1ccc(C(C)c2nc3cc(Cl)ccc3n2Cc2ccccc2)cc1 +Nc1nc(C(=O)NCc2ccccn2)cc(-c2ccccc2F)n1 +Cc1ccccc1C1CCc2cc(Oc3nc(C)c(C(=O)NCCO)s3)ccc2O1 +O=C(NCC(CC1CC1)c1ccc(C(F)(F)F)nc1)c1cccc(Cl)c1F +COc1cc(OC)c(C(=O)c2ccc(F)cc2)c(O)c1Br +Nc1cccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)c1 +O=C(NCCCNCCCCCNCCCNC(=O)NCc1ccccc1)NCc1ccccc1 +N=C(NCCCCCCCCCCCCNC(=N)C1CC1)C1CC1 +N=c1c2nc[nH]c2nc2n1CCC2=Cc1ccccc1Br +O=C(O)c1nc2c(O)nc3cc(Cl)c(-n4cnnc4)cc3n2n1 +CN(CC(CCN1CCC(c2nc3ccccc3[nH]2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +Cn1ccc(S(=O)(=O)NC(CNC(=O)C2=NOC(CCCCN=C(N)N)C2)C(=O)O)n1 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+CCN(c1nc(C)cc(-c2ccccc2C(F)(F)F)n1)c1ccc(S(C)(=O)=O)cc1Br +Nc1nc2c(s1)CCCC2C(=O)Nc1ccc(CC2CCC(C(O)c3ccccc3)N2)cc1 +CCOC(=O)C1CCCN(c2cccnc2Oc2ccc(Nc3ccccn3)cc2)C1 +COc1cc2c(Oc3ccc(NC(=O)c4cn(-c5ccccc5OC)cn4)cc3F)ccnc2cc1OCCCN1CCOCC1 +COc1ccccc1N1CCN(Cc2ccc(CN3CCCCCC3=O)o2)CC1 +O=C(O)Cc1nn(Cc2nc(-c3c(F)cccc3Cl)no2)c(=O)c2ccccc12 +COc1cccc(C(C)Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +Cc1c(Cl)cccc1N1CCN(CCCNC(=O)c2nc(C)n(CC(C)C)c2C)CC1 +CCc1c(C)[nH]c2cc(OCCOc3ccccc3)c(C)cc2c1=O +CC(C)(C)C(=O)N(CC=Cc1cnc2c(c1)CC1(C2)C(=O)Nc2ncccc21)C1CCCCCC1 +Cn1cc(-c2ccn3c(-c4ccccc4)c(-c4ccc(C5(N)CCC5)cc4)nc3c2)cn1 +O=C(NCCc1c[nH]c2ccc(O)cc12)Oc1cccc(-c2ccccc2)c1 +CC1CNc2c(sc3ccc4oc(-c5ccccc5)cc4c23)C(=O)N1 +O=C(NCC(c1cnc(C(F)(F)F)nc1)N1CCC(F)(F)CC1)c1c(Cl)ccc2nc(N3CCC(O)C3)ccc12 +CC(=O)NCCNc1nc(-c2ccccc2)nc2[nH]c(C(=O)N3CCN(CCCc4ccccc4)CC3)cc12 +COCCOCCOc1ccc(-c2cnc(N3CCOCC3)c3nc(CCc4ccc5ccccc5n4)cn23)cc1 +CC(C)CC(NC(=O)CCN(C)C)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C2COCC2c2ccc(Cl)cc2)CC1 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+O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(Cl)c(-c2cc[nH]n2)c1 +COc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2cc1OCCCCCCn1ccnc1[N+](=O)[O-] +COc1cc(C(N)=O)ccc1NC(=O)C1NC(CC(C)(C)C)C2(C(=O)Nc3ccncc32)C1c1cccc(Cl)c1F +CC#CCOc1ccc(S(=O)(=O)C2CCC(S)C2)cc1 +CC(C)OC(=O)N1CCC(C(NS(=O)(=O)c2ccc(-c3ccc(OC(F)(F)F)cc3)s2)C(=O)O)CC1 +COC(=O)c1ccccc1N1CCC(CNc2nccc(C)c2NC(=O)CC#N)CC1 +O=C1NC(CCN2CCN(c3ccccc3)CC2)c2ccccc21 +N#Cc1cc(S(=O)(=O)Nc2nncs2)ccc1Oc1ccc(Cl)cc1-c1ccnc(N2CCC2)c1 +OC(CN1CCN(CC=Cc2ccccc2)CC1)Cn1c2ccc(Br)cc2c2cc(Br)ccc21 +O=C(Nc1ccc(Oc2ccc(Cl)cc2)c(Cl)c1)c1cc([N+](=O)[O-])ccc1O +C=CC(=O)Nc1cc(N)nc(Sc2c(OCC)nc(N3CCN(C)CC3)nc2OCC)n1 +CC(C)C(NC(=O)NC1CCCC1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1 +Cc1c(C(=O)NCCc2ccc(Cl)cc2)nn(-c2ccc(Cl)c(Cl)c2)c1-n1c(C)ccc1C +CN1CCN(CCc2ccc(C3=CCC4CN(Cc5ccccc5)CC34)cc2)CC1 +COc1n[nH]c2cc(NC(=O)NCc3c(C)cccc3Cl)ncc12 +CC12C=CC(=O)C=C1C1(CC1)CC1C2CCC2(C)C(c3cccnc3)=CCC12 +Cc1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)COc3ccc(O)cc3)cc2)cc1 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+CC(=O)OCC1OC(CC(=O)C=Cc2ccc(C(F)(F)F)cc2)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C=O)cc4)cc3)cc2n(CCC)c1=O +Oc1ccc(-c2nc3c4c(ncn3n2)-c2ccccc2CC42CCCC2)cc1 +COc1ccccc1CNc1ccc2c(c1)n1ncc(C)c1n[n+]2[O-] +CC1=C(CCN2CCCC2)c2cc(NS(=O)(=O)c3c(Cl)nc4sccn34)ccc2C1 +CC1CCC(Cn2c(N3CCCC3c3cnn[nH]3)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +Cc1ccc(-n2nccn2)c(C(=O)N2C3CCC2C(COc2cccnc2)C3)n1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3c(F)cccc3OC)ccc2[nH]1 +O=C(NCC1CCN(CCc2ccccc2)CC1)c1n[nH]c2ccc(-c3ccccc3F)cc12 +CN1Cc2c(C3=CCN(C4CC(CC(=O)O)C4)CC3)[nH]c3ncc(F)c(c23)-c2cc(F)ccc21 +Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)OCCCN)O2)c(=O)[nH]c1=O +CC1CC(N)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3ccc(O)cc3F)n2)C1 +COc1cc2nc(N(C)CCSSCCN(C)C(=O)c3ccc(CCl)o3)nc(N)c2cc1OC +O=C(NCc1ccc2cc(C(=O)NO)sc2c1F)c1ccccc1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(S(C)(=O)=O)cc4)cc23)c1F +CC(CNC(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(C(=O)OC(C)(C)C)CC1 +CN(C)CCNc1nc2cc(O)ccc2c2c1C(=O)c1ccccc1-2 +Cc1cc(F)c(NC(=O)c2ccsc2)cc1Nc1ccc2c(c1)OCc1ccccc1C2=O +COc1ccc(CC(N)C(=O)N2CC(F)CC2C#N)cc1 +Cc1c(Cl)cccc1S(=O)(=O)NCC1(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)CC1 +COc1cnn(C)c(=O)c1-c1ccc(CC(NC(=O)c2c(Cl)cccc2Cl)C(=O)O)cc1 +COc1ccc2c(c1F)C(=O)N(CC1(C#Cc3ccc(CN4CCOCC4)nc3)NC(=O)NC1=O)C2 +Fc1ccc(C(OCCC2CCN(CC3Cc4ccccc4CN3)CC2)c2ccc(F)cc2)cc1 +C=C(CC)C(=O)c1ccc(OCC(=O)NCCc2ccc(O)c(OC)c2)c(Cl)c1Cl +CCCCc1oc2ccccc2c1C(=O)c1ccc(OCCNCC)c(I)c1 +COc1ccc2c(c1)CC(NCCN1CCC(CNS(=O)(=O)c3cccc4ccccc34)CC1)CCC2 +Cc1c(Oc2ccc(Cl)cc2)c2cccnc2n1Cc1cc(OC(C)C(=O)O)ccc1Cl +CCCCCN(C)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12 +Nc1ncc(-c2cc(Nc3cnc4ccccc4c3)nc(N3CCOCC3)n2)cn1 +O=C(N1CCN(Cc2ccccc2)CC1)N1CC(OC(c2ccc(Cl)cc2)c2cccnc2Cl)C1 +CN(C)C(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccc(OCc3ccccc3)cc21 +COc1ccc(-n2nc(C(=O)N3CCCC3)cc2-c2ccc(Cl)cc2)cc1 +COc1ccc(CCCO)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1 +O=C(Cc1ccc(O)cc1)NN=C1C(=O)Nc2ccc(S(=O)(=O)NCCN3CCOCC3)cc21 +COc1ccc(-c2ccc(C(=O)N(C)c3cccc(OC)c3)s2)cc1 +Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2cc(Cl)ccc2Cl)cc2[nH]c(C3(C)CC3)nc12 +CCCCN1C(=O)C(=CC=Cc2ccco2)C(=O)NC1=S +CNC(=O)c1ccccc1Nc1cc(Nc2ccc(N3CCOCC3)cc2OC)ncc1C#N +CC(N)C(=O)NC1CCCCC2CCC(C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O +O=C(Nc1csc(-c2nncn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CCC(C(F)(F)F)CC2)cn1 +COC(=O)C1=C(Nc2ccccc2F)OC(=Cc2c[nH]c3ncccc23)C1=O +Cc1c(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cnn1C +CC(=O)OCn1nnc(-c2ccc(F)c3c(C(=O)C(=O)N4CCN(C(=O)c5ccccc5)CC4)c[nH]c23)n1 +C=CCOc1ccc(C(=O)C=Cc2ccc(OC)cc2OC)cc1 +O=C(c1ccc2nn[nH]c2c1)N1CCCC2c3ccccc3CCC21 +CCCCCCN1C(=O)C(CCOc2ccccc2CC(=O)O)Oc2ccccc21 +COc1c(Cl)cc(N2CCN(CCCCc3c[nH]c4ccc(C(N)=O)cc34)CC2)cc1Cl +O=C(O)c1ccc2c(c1)CCc1cc(C=Cc3ccccc3)ccc1-2 +CCNC(=O)C1OC(n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(NCCc4ccccc4)nc32)C(O)C1O +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnc2ccccn12 +CC(C)CC(C(=O)NC1(C#N)CC1)c1cccc(-c2ccc(N3CCNCC3)cc2)c1 +Cc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(C(=O)CN(C)C)CC2)c(=O)n4C)cn1 +CC(=O)Nc1ccc2c(c1)C1(C)CCN(Cc3ccccc3)C(C2)C1C +COc1cc(NC(=O)C2COc3ccc(Cl)cc3C2)ccc1-c1cn[nH]c1 +COC(=O)CCC(=O)OC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +COC(=O)CCSC(=O)C1(C(O)C2C=CCCC2)NC(=O)C(CCCl)C1(C)O +COc1cc(C(F)(F)F)cc(SC)c1C(=O)NC1COCCC1NC1(C)CCCC1 +CC1(C)C(=O)Nc2nc(-c3nn(Cc4ncccc4F)c4cc(Cl)ccc34)nnc21 +CC(C)(C)c1ccc(N(Cc2ccc(C(=O)NCC(O)C(=O)O)cc2)C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1 +COc1ccc(CNC2CCN(CCN3CCCCC3)C(c3ccc(OCc4ccccc4)cc3)C2)cc1OC +CC1(N2C(=O)c3ccccc3C2=O)CCC(=O)NC1=O +CC(=O)NC1CCCN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)C1 +FC(F)(F)c1ccc2nc(COc3cc4c(cc3Cl)OCO4)[nH]c2c1 +Cc1c(Cc2ccccn2)nnc(N2CCN(c3cnc(C(C)(C)O)cn3)C(C)C2)c1C +COc1cc(-n2cnc3cc(-c4ccc(F)cc4)sc3c2=O)ccc1OCCN1CCCC1 +CC(C)c1c(Sc2ccccc2)n(COCc2ccccc2)c(=O)[nH]c1=O +O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Cl)ccc1O +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ON=C(C)N +COc1ccc(C2CC2COc2nc(C)ncc2-c2cc(=O)n(C)cc2SC)nc1 +COC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 +COc1ccc(C#Cc2cccc(C#Cc3ccc(OC)cc3)[n+]2C)cc1 +COc1cnc(N2CCC(C3CC3COCc3ccc(S(C)(=O)=O)cc3F)CC2)nc1 +O=C(COc1ccccc1)N1CCCCC1c1csc(-c2n[nH]c3ccccc23)n1 +COc1cc(-c2cc(-c3ccc(N4CCNCC4)cc3)cnc2Cl)cc(OC)c1OC +COc1ccc(-c2cn(CCC(C)(C(=O)NO)S(C)(=O)=O)nn2)c(F)c1 +CCc1c(C(F)(F)F)nn(C)c1Oc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F +O=C1N(CCCCN2CCN(c3nsc4ccccc34)CC2)CSC12Cc1ccccc1C2 +Cc1c(Oc2ccc(Cl)cc2)c2cccnc2n1Cc1ccc(F)c(OC(C)C(=O)O)c1 +C[N+]1(C)C2CCC1CC(CC(O)(c1cccc(Cl)c1)c1cccc(Cl)c1)C2 +Cc1ccc(NC(=O)c2ccc(NC(=O)CCl)cc2)cc1Nc1nccc(-c2cccnc2)n1 +Clc1ccc2c(c1)-c1ncnn1Cc1c(C3CC3)ncn1-2 +CCOC(=O)N1CCN(C(=O)c2ccc(-c3ncnc(CC)c3C#Cc3ccc(N)nc3)cc2C)CC1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCC(O)C2)c(-c2cncc(F)c2)c1 +Cc1cccc(C2=NC(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)C(=O)Nc3c(Cl)cccc32)c1 +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3cccc4[nH]nc(C)c34)cc(C)c2C1 +O=C1CCc2cc(Nc3ncc(C(F)(F)F)c(NCc4ccccn4)n3)ccc2N1 +COc1ccc(C(NC(=O)COc2ccc(C)cc2)c2cc(Cl)c3cccnc3c2O)cc1 +NC(=O)c1c(NC(=O)c2ccc(Cl)cc2)sc2c1CCCC2 +COc1cccc(Cn2cnc3c(N(C)C)nc(C(F)(F)F)nc32)c1 +CN(C)C1CCN(c2ccc(Nc3ncc4c5ccnc(O)c5n(C5CCC(C)(C)CC5)c4n3)nn2)CC1 +Clc1ccc2c(NCCNc3nc(Cl)cc(Cl)n3)ccnc2c1 +O=S(=O)(NCC1CC1)c1ccc(NN2CCOCC2)cc1C(F)(F)F +CCOc1cc(CN2CC3(CC(c4ccc(C(=O)O)cc4)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +Cc1cc(N(C)C)nc2ccc(Cc3cnc(N)nc3N)cc12 +Cc1cn(Cc2ccc(F)c(F)c2)c2c(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 +CC(C)C1CCNc2cc3nc(O)cc(C(F)(F)F)c3cc21 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(COc3ccc(NC(=O)OC(C)(C)C)cc3)cc2)cc1)C(=O)O +CCCCCCCCCCCCCC(=O)NCCc1ccc(OS(N)(=O)=O)cc1 +Cc1cccc(CC(NC(=O)C(c2ccccc2)c2ccccc2)C(=O)NC(C#N)CCCc2cccc(C(=O)O)c2)c1 +Clc1ccc(C=Cc2ccc(-c3ccc(I)s3)s2)cc1 +COc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)cc1OC +CCOc1nc(-c2ccccc2)ncc1C(=O)N1CCC(c2nc3ccccc3[nH]2)CC1 +c1ccc(CCN2CC(c3[nH]c(-c4ccccc4)nc3-c3ccccn3)CCC2c2ccccc2)cc1 +Nc1nc(N)c2c(CCCc3csc(C(=O)NC(CCC(=O)O)C(=O)O)c3)coc2n1 +CC(C)c1ccc(-c2cc(C(=O)O)c3cc(Br)ccc3n2)cc1 +CC(C)Oc1ccc(Nc2ncc(C(=O)NN)c(=O)n2Cc2ccc(Cl)cc2)cc1F +CNC(=O)C(O)C(O)c1cn(-c2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)c2ccccc12 +COc1ccc(Nc2cc(S(=O)(=O)O)c(N)c3c2C(=O)c2ccccc2C3=O)cc1 +FC(F)(F)c1ccc(Nc2noc3cc(-c4cccc(C(F)(F)F)c4)ccc23)cc1 +O=C(C=Cc1ccc(O)c(O)c1)NCC(NC(=O)C=Cc1ccc(O)c(O)c1)C(=O)O +COc1cccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)c1 +CC1COc2c(NCCCc3ccccc3)c(F)c(N)c3c(=O)c(C(=O)O)cn1c23 +CNc1nc(Nc2ccc(C(=O)N3CCN(S(C)(=O)=O)CC3)cc2OC)ncc1Cl +CC(=O)Nc1ccc(C)c(-c2ccc(C(=O)NCC3CC3)cc2)c1 +CN(C1CCc2c(CC(=O)O)c3cccc(F)c3n2C1)S(=O)(=O)c1ccc(F)cc1 +CCCN1CCC23Cc4nc5ccccc5cc4CC2(O)C1Cc1ccc(O)cc13 +CCN(CC)C(=O)C1CCC2C3CC=C4N(O)C(=O)CCC4(C)C3CCC12C +COc1cc2[nH]c(C)c(-c3cccc(CO)c3)c(=O)c2cc1Cl +NS(=O)(=O)c1ccc(-n2cc(C=NNc3nc(-c4cc5ccccc5oc4=O)cs3)c(-c3ccc(Cl)cc3)n2)cc1 +O=C(O)c1ccc(CN(CC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2F)cc1 +c1cc(-c2cnc(N3CCCC3)c(N3CCNCC3)n2)c2cc[nH]c2n1 +O=C(O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1 +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CCCC(C)(C)C)CC(O)CC1O +COc1cccc(C=C2SC(c3ccccc3)=NC2=O)c1O +O=C(Nc1cncc(Oc2cncc(F)c2)n1)c1cc(Cl)ccc1F +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N4CCCC4)ncc3Cl)C2)cc1 +O=C(Cc1ccc(O)cc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc(O)cc3)s2)s1 +CC(C)[S+]([O-])c1ccccc1Nc1nc(Nc2ccc(CN3CCN(C)CC3)cc2)ncc1Cl +O=C(NCCCCN1CCC1)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COc1cccc(CNC(=O)c2cc3ccc(-c4cn[nH]c4)nc3n2CCN(C)C)c1 +NS(=O)(=O)c1ccc(-n2cc(-c3ccc(Br)cc3)c(C(F)(F)F)n2)cc1 +COc1cc(-c2cccc(OC)c2Cl)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +COc1cccc(CN2CCN(CCOc3cccc4nc(C)ccc34)CC2)c1 +COCC(COC)n1cc(Cl)nc(Nc2c(Cl)cc(OCF)cc2Cl)c1=O +Cc1cc2cc(F)ccc2nc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +CC(=O)NC1C(COCCCCc2ccccc2)NC(CO)C(O)C1O +CCCNc1nccc(N2CCC(Oc3ccc(C(C)C(=O)NC4CC4)cc3)C2)c1F +Cc1ccc(-c2nc(C(C)(C)C)c[nH]2)cc1S(=O)(=O)N1CCOCC1 +COc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccccc3)nn2)CC1 +COc1cc(OCc2csc(N3CCC(F)CC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)C2=NOC(CCCCNc3ncc[nH]3)C2)C(=O)O)c(C)c1 +CCOc1cc(N2CCNCC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1Cc1ccccc1)CC2 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ncc[nH]3)cc12 +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2oc(CN3CCCC3)cc2c1 +[C-]#[N+]c1cc(-c2ccnc(Nc3ccn(C4CCNCC4)n3)c2)ccc1OCC1CCC1 +CCc1c(C)nc(-c2ccccc2O)n(CCc2ccccc2)c1=O +COc1cccc(-c2nccnc2C2CN(c3nc4ccccc4cc3C#N)C2)c1 +Cc1c(Cc2c(CO)nc3c(N)cc(N4CCOCC4)nn23)cccc1C(F)(F)F +CCc1nc2cc3c(cc2o1)CCN(CCCSc1nnc(-c2ocnc2C)n1C)CC3 +CCCCc1nc2[nH]cnc2c2nc(-c3ccc(OC)cc3)nn12 +O=C(O)c1cc(C(F)(F)F)ccc1N1CCC(Cc2ccc(F)cc2)C1 +Clc1ccc2[nH]c3c(NCCC4=CCCCC4)ncnc3c2c1 +N=C(N)c1cccc(OCCN(Cc2ccccc2)C(=O)c2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +COC(=O)NC(C)Cc1ccc(C#Cc2cnc(NC(C)C)nc2)cc1 +CC(=O)c1ccc(Cn2nc3c(c2Nc2ccc(F)cc2)C(=O)N(C)C2=NC(C)(C)CN23)cc1 +COc1ccc(OC)c(-n2c(-c3ccccc3)nc3ccccc3c2=N)c1 +Cc1ccc(-c2cnc(C(=O)CCCCCCc3ccccc3)o2)nc1 +CS(=O)(=O)c1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)cn2)cc(C(F)(F)F)c1 +Cc1nc2cc(Nc3cc(C4CCCNC4)nc4c(-c5cnn(C)c5)cnn34)ccc2s1 +Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(Cl)c(Cl)c1 +CC(=O)c1ccccc1-c1ccc(-c2ccc3c(c2)c(C)c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)cc1F +O=C(NCC1CCN(c2ccncc2)CC1)c1ccc(F)c(OCCc2ccc(Br)cc2)c1 +COc1cc(Br)c(OC)c(C(=O)NCC2CCCN2Cc2ccc(F)cc2)c1O +COc1ccc2cccc(CCNS(=O)(=O)c3ccc(OC)c(N4CCN(C)CC4)c3)c2c1 +O=C(Nc1cccc2cnccc12)NC(c1ccccc1)c1ccc(C(F)(F)F)cc1 +CCOC(=O)N1CCN(CCCOc2ccc(C(=O)Cc3ccccc3)cc2)CC1 +CC1(C(=O)O)CCC(CC(=O)N2CCc3c(n(Cc4ccc(C(F)(F)F)s4)c4ncccc34)C2)CC1 +O=C1c2c(O)c(O)cc(S(=O)(=O)NCCN3CCOCC3)c2CN1Cc1ccc(F)c(Cl)c1 +CC(C)Cc1nc(-c2ccc(CN3CCC(n4c(O)nc5ccccc54)CC3)cc2)c(-c2ccccc2)nc1O +CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(C)C(=O)O)cc3)c2)CC1 +CC#CC1CC2Cc3[nH]ncc3C(C1)N2S(=O)(=O)c1ccc(Cl)cc1 +Cc1cc(C(N)=O)ccc1OC1CC2CCC(C1)N2Cc1ccccc1 +O=C(O)C1C2CN(C3CCC4(Cc5ccccc5Cc5ccccc54)C3)CC21 +O=C(NCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)c1ccc(Cl)cn1 +CC1(C)Oc2ncnc(N)c2N=C1c1ccc(C(C)(C)C(=O)O)cc1 +O=c1c2cccn2c2cccc(F)c2n1CCN=C(S)Nc1ccc(Br)cn1 +Cc1nsc(-c2ccc(N3CCN(c4cccc(F)c4)CC3)nn2)n1 +[N-]=[N+]=Nc1ccc(N2CCOc3cc(S(=O)(=O)Nc4nccs4)ccc32)c(Br)c1 +Nc1ccccc1C(=O)CCCN1CCC2C(C1)c1cccc3c1N2CCO3 +COc1cccc(Nc2nc3cccc(-c4c(F)cccc4OC)c3o2)n1 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+O=C(NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1)c1ccc2ncccc2c1 +Cc1[nH]c(-c2ccccc2Oc2ccc(Cl)cc2)cc1C(N)=O +Nc1ncc2cc(-c3nccnc3OC3CN(c4ccc5ccccc5n4)C3)ccc2n1 +O=C(O)c1cc(-c2cccs2)n(Cc2cc(Br)ccc2OCc2ccccc2)n1 +CCOCCn1nc(C)c2nc(N3CCNCC3)nc(Nc3cc(C)ccn3)c21 +Cc1cc(Oc2cnc(NC(=O)C(OC3CCOC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)ccc1C(=O)O +CC1CN2C(=O)c3c(cccc3C(F)(F)F)C2CN1 +CNc1cc(Cn2c(C(=O)c3cc(C)cc(Cl)c3)c(C(C)C)c(=O)[nH]c2=O)ccn1 +CC(=O)Nc1c(O)[nH]c(=Nc2ccc(OC(C)C)cc2)n(Cc2ccc(Cl)cc2)c1=O +CN1CCN(C(=O)C(COCc2ccncc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)CC1 +O=c1[nH]c2ccc(Cl)cc2n1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CC1(C)OC(=O)N(C2CCC(n3c(=O)[nH]c4cnccc43)CC2)C1c1ccccc1 +C[S+]([O-])c1sc(C(=O)O)c(-c2ccc(C(C)(C)C)cc2)c1C#N +C=CCNC(=O)Nc1nc2cc(-c3cccnc3)c(OCCN3CCOCC3)nc2s1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1cnc(-c2ncc(C(F)(F)F)[nH]2)c(F)c1 +CC(C)Oc1ccc2c(c1)c(CN1CCN(C)CC1)cn2S(=O)(=O)c1ccccc1Br +COc1ccc(OCCN(CC(=O)NCc2ccccc2)Cc2ccc(F)c(F)c2)cc1OC +Cc1nc(-c2ccncc2)sc1C(=O)N1CCCC1c1cccc(C(=O)Nc2nc3c(s2)CC(N2CCOCC2)CC3)c1 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+CC(=O)N1CCC(c2cc(-c3cnc4[nH]cc(C(F)(F)F)c4c3)nn2C(C)C)CC1 +O=C(CCCC(=O)NCCCCNc1c2ccccc2nc2ccccc12)NCCCCNc1c2ccccc2nc2ccccc12 +N=C(N)c1ccc(CC(=O)CN2CCCCC(NS(=O)(=O)c3ccc4ccccc4c3)C2=O)cc1 +O=c1cc(-c2ccccc2)oc2cc(OCCCCN3CCN(CCCNc4c5c(nc6ccccc46)CCCC5)CC3)ccc12 +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccc(-c3cccnc3)cc2o1 +COc1ccc(C#Cc2cc(-c3nn(CCCN4CCOCC4)c4c3CN(S(C)(=O)=O)CC4)ccc2Cl)cc1 +COc1cccc(NC(=O)NC2C3CCN(CC3)C2Cc2cccnc2)c1 +Cc1cc(COC(=O)C2N3C(=O)C(NC(=O)COc4ccccc4)C3SC2(C)C)on1 +Cn1cnc(Nc2ncc(Cl)c(NC3CCC4(CC3)CCN(C(=O)CC#N)CC4)n2)c1 +Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)ccc(F)c2F)cc1 +COc1ccc2nc3cc(Cl)ccc3c(NCCCN(CCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)CC3CC3)c2c1 +Cc1ncn(CC(=O)NCCN)c1Cn1c(C)ccc(NS(=O)(=O)Cc2ccccc2)c1=O +CC1(C)Oc2ccc(C#N)cc2C(N2CCCC2=O)C1O +O=c1[nH]nc(CN2CCOC(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2c2ccccc2)[nH]1 +COc1ccc(NC(=NC#N)N2CCC(=C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)cc1 +CCN(CC)C(=O)C1CCC2C3CNC4=CC(=O)C5CC5C4(C)C3CCC12C +CC1CC(CS(=O)(=O)N2CCC(CO)CC2)CCC1N(C)c1ncnc2[nH]ccc12 +COc1cc(O)ccc1C=NNC(=O)Cc1cccc(O)c1 +CNc1nc(-c2nc3cnc(N4CCOCC4C)cc3n2C(C)COC)cn2c(C)nnc12 +O=C(NCCn1ccnn1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(CN(Cc1ccc([N+](=O)[O-])cc1)S(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)NO +CC1CN2c3c(cc4c(C5CC5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CCc1c(Sc2ccccc2)n(COCC2CCCCC2)c(=S)[nH]c1=O +CC(=O)N1CCC(C(=O)N(CCCN2CCC(C(=O)NCc3ccc(Cl)cc3)CC2)c2cccc(Cl)c2)CC1 +Oc1nc2cnc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nc2[nH]1 +O=C(NCCn1cncn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(c1nn2c(C(F)(F)F)cc(C3CC3)cc2c1Cl)N1CCC2(CC1)OCC1(CO2)CC(O)C1 +Cc1cc(C)cc(C(=O)N2CCN(C(=O)CNC3CCN(Cc4cc[nH]c4)CC3)C(c3ccc(Cl)c(Cl)c3)C2)c1 +CNc1n[nH]c2cc(NC(=O)NC(COC)c3ccc(F)cc3)ncc12 +Nc1nc(-c2cc(N3CC(O)C(O)C3)ccc2O)cc(C2CCCCC2)n1 +O=C(c1ccc(Cn2c(=S)[nH]c3ccccc3c2=O)cc1)N1CCN(c2ccccn2)CC1 +Cc1csc2ncnc(N3CCC(CNCCC4CCCN4C)CC3)c12 +COc1ccc(OC)c(NCc2c[nH]c3nc(N)nc(O)c23)c1 +Cc1nc2ccccc2nc1CCc1nc(N2CCCC2)nn1C +COc1cc(Oc2ccncc2)c2c(Nc3c(Cl)ccc4c3OCO4)ncnc2c1 +CC(C)N(C)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +O=S(=O)(Nc1nncs1)c1ccc(Oc2ccc(Cl)cc2-c2ccn[nH]2)c(Cl)c1 +O=C(NC1CCN(CCCC(F)(F)F)CC1)c1cc(-c2c(O)cc(O)cc2Oc2ccc([N+](=O)[O-])cc2)on1 +CS(=O)(=O)c1ccc2nc(-c3ccc(-c4cccs4)cc3)[nH]c2c1 +NC1(c2ccc(-c3c(-c4ccccc4)ccn4ccnc34)cc2)CCC1 +Cc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)N(C)C3CCN(C)CC3)cc2)c(C)c1 +CCc1nccc(-c2ccc(C(=O)N3CCN(CC4CC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CSc1cccc(NC(=S)N(Cc2ccc(C)cc2)Cc2ccccn2)c1 +COc1ccc2c(c1)[nH]c(=O)n2CC(=O)Nc1ccc2c(c1)CC1(C2)C(=O)NC(=O)N1C +COc1ccc(Cc2cc(C34OCC(CO)(O3)C(O)C(O)C4O)ccc2Cl)cc1 +CC1CC(c2cc3c(C(F)(F)F)cccc3s2)CCN1CC(O)COc1cccc2[nH]ccc12 +CC(=NOC(C)C)c1ccc(Sc2cc(F)cc(C3CCOCC3)c2)cc1 +O=S(=O)(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)c1ccc(F)cc1 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(OCc3ccccc3)cc2)cc1 +CC(C(=O)OC1CC[N+](C)(C)CC1)(c1ccccc1)N1CCCC1 +O=C(O)CC1CCC(c2ccc(-c3noc(-c4ccc(C5CCCC5)cc4F)n3)cc2)N1 +CCCc1cc(NCC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)n[nH]1 +CN(C)c1ccc(-c2cc(-c3ccccc3)c3c(N)ncnc3n2)cc1 +CN(CCCCn1nc(-c2ccccc2)oc1=O)Cc1ccccc1 +Cc1ccc2c(c1)sc(-c1ccc(N(C)C)cc1)[n+]2C +Fc1ccc2c(c1)C(Nc1nc3ccccc3[nH]1)CCC2 +O=c1cc(-c2ccccc2)oc2cc(O)c(O)c(O)c12 +Fc1cccc(F)c1C1CCC(N2CCN(c3ccccn3)CC2)CC1 +CC1=C2CC3C(CC=C4CC(O)CCC43C)C2CCC12OC1(C)CC(C)CNC1C2C +CNC(=O)C1OC(n2cnc3c(NOC)nc(C#Cc4ccccn4)nc32)C(O)C1O +CC12CCC(COc3cccc(-c4cn(C5CC(CO)C5)c5ncnc(N)c45)c3)(CC1)O2 +O=C(NC1COC1)c1cc2c(N3CCCC3c3ccccn3)ccnc2[nH]1 +Cc1cc(NCc2c(F)cccc2Cl)c2cccc(C(N)=O)c2n1 +Cc1ccc(-c2cc(C(=O)NCc3ccc(C)nn3)cc3c2ccn3C(C)C)nc1 +COc1ccc(NC(=O)c2ncc(Cc3cccc(C(F)(F)F)c3)s2)cc1OCCO +COc1cc(N2CCN(C)CC2)ccc1Nc1nc(N)n(C(=O)NCc2ccccc2S(C)(=O)=O)n1 +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ONC(C)C +Cc1ccc(N2CCOC(C(O)C(=O)Nc3ccc(C(=N)N)cc3)C2=O)cc1 +CCCCc1nc(Cl)c(CC(=O)O)n1Cc1ccc(C(=O)O)cc1 +COCCCCN1CCN(C(=O)c2cc3c(cc2C)[nH]c(=O)c2cnn(C4CCC4)c23)CC1C +COC(=O)c1ccnc(-n2nccc2OCc2ccc(Cl)cc2)c1 +Clc1ccc(-c2ccc(-c3nccn3-c3ccc(C4CCCCN4)cc3)o2)cc1 +OCCCNc1nc(Nc2ccccc2)nc(Nc2ccc(F)cc2)n1 +Cc1nc(N)c2cc(CN(C)C)cc(C(=O)Nc3ccn[nH]3)c2n1 +COCCOc1cc2ncnc(NC3=CC(=O)C=CC3=O)c2cc1OC +Fc1ccc2sc3c(c2c1)CCN(Cc1cnccc1C1CC1)C3 +COC(=O)C=Cc1ccc2c(c1)C(=O)C(=O)N2Cc1cccc(Br)c1 +N#Cc1ccccc1Oc1ccc(Nc2ncnc3cc[nH]c23)cc1Cl +Cc1ccc(-c2c[nH]c(C3(NCC4CCCCC4)CCCC3)n2)cc1 +NC(=O)c1ccc2[nH]c(-c3ccc(OC4CCCN(Cc5ccccc5)C4)cc3)nc2c1 +O=C1NCCc2[nH]c(-c3ccnc(-c4cncnc4)c3)cc21 +Cc1ccc(-c2cc(C(=O)NC(C)c3cnccn3)cc(N3C(=O)OCC3C(C)C)c2)c(F)c1 +CC(C)(O)c1c(C(N)=O)nc2n1C1CC(C1)c1cc(F)ccc1-2 +CC(C)(C)c1ccc(C(=O)Nc2cn3cc(Br)ccc3n2)cc1 +CCc1cccc(Nc2nc3cc(C(=O)O)ccc3c3sccc23)c1 +CC(C)N1CCN(c2cccc(S(=O)(=O)N3CCN(c4ccc(F)cc4C(F)(F)F)CC3C)c2)CC1 +Cc1ccc(N2CCc3ncnc(NCc4cccc(-n5cnnc5)c4)c3C2)c(C#N)c1 +CC#CCn1c(N2CCCC(N)C2)cc(=O)n(Cc2ccc3ccc(Cl)cc3n2)c1=O +CCCCCCCCCCCCCCOCC1COC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)C1 +Cn1c(OCC2CCN(c3ccc(CN4CCCCC4)cc3)CC2)nc(-c2ccncc2)cc1=O +CC(C)CNC(=O)c1ccc(-c2ccc(-c3ccco3)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2cc(C(F)(F)F)c3cc(F)ccc3n2)c1 +C=C(Br)C(=O)Nc1ccc(C(=O)C=Cc2ccc(OC)cc2OC)cc1 +COc1ccccc1N1CCN(CC2COC3(CCN(c4ccccn4)CC3)O2)CC1 +Cn1c(NC(C)(C)C)nc2c(-c3cc4c([nH]3)CNC4=O)cccc2c1=O +CC1CN(Cc2c[nH]nc2-c2ccc3c(c2)CNC(=O)O3)CCN1c1cccc(C(F)(F)F)c1 +OC1(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CCN(Cc2ccccc2)CC1 +O=C(NC1CCCC(CO)C1)C1CCN(c2nc3cc(Cl)c(-c4ccc(OC(F)(F)F)cc4)cc3o2)CC1 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2OC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1 +COC(=O)CCC(=O)N(O)c1cccc(OCc2ccc3ccccc3n2)c1 +COC(=O)c1c(NC(=O)CC2SC(=N)NC2=O)sc(C)c1C +O=c1[nH]c(-c2ccc(F)cc2Cl)nc2c1oc1ccc(Br)cc12 +CCOc1cc(-c2c(C)noc2C)cc(C(O)c2ccccc2)c1 +O=C(Nc1ccc(Br)cc1)c1csc(Cc2c(Cl)cccc2Cl)n1 +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)N4CC5CC4CN5C)c4ccc(C)cc34)cc2)c1C +CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C4CC4)cn3)c2)c2cnc(N)nc21 +Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)c5cccc(Cl)c5)cc4)csc23)cn1 +CCCc1cc(C(=O)O)ccc1OCCCCCCc1cccc(O)c1O +COC(=O)COc1ccc(-c2cc3ccccc3[nH]2)cc1 +O=C(O)CCc1cc2cc(-c3cccc(OC4CCC4)c3)ccc2o1 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+Cn1c(-c2cccc(-c3ccccc3)c2)nnc1C1(c2ccc(Cl)cc2)CCC1 +O=C(c1ccc(-c2cccc(OC(F)(F)F)c2)cc1)N1CCN(c2ncccn2)CC1 +COc1cc(C(F)(F)F)ccc1-c1ccc(Cn2cncc2CN2CCN(c3cccc(Cl)c3)C(=O)C2)cc1 +COc1ccc(CC2CCOCC2)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(CN(C)C)cc2)c1 +O=C(CNC(=O)c1ccc(OCc2ccccc2)cc1)NC1CCCc2ccccc21 +CC1CC1C(=O)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)C1 +CC(Cc1ccccc1)(C(=O)NO)C(=O)NCCCCc1ccccc1 +CNc1nc(N)nc2nc(-c3c(F)cccc3C(F)(F)F)ccc12 +CNC(=O)c1nn(C)c2c1CCc1cnc(Nc3cc(N4CCN(C)CC4)ccc3OC)nc1-2 +CC1(O)CN(C(=O)N2CCC(C)(N3CCc4c(-c5cnc(N)nc5)nc(N5CCOCC5)nc43)C2)C1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1ccc(Cl)cc1 +O=C1CC(NC(=O)C2(C(=O)NNC(=O)c3cccc4ccccc34)Cc3ccccc3C2)C(O)O1 +Cc1ccc(S(=O)(=O)NC(CNC(=O)N2CCC3(CC2)CCN(c2ccc(C(=N)N)cc2)C3=O)C(=O)O)cc1 +COc1ccc(-n2c(-c3ccc(S(N)(=O)=O)cc3)coc2=O)cc1 +CS(=O)(=O)c1ccc(CNCC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +CN(C)CCNC(=O)c1cccn2c(=O)c3cc4ccccc4cc3nc12 +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2cc(C)c(C)c3ccccc23)c(Cl)c1 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+CCCCN1CC(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2NCCN(Cc3ccccc3)C2=O)CC1=O +O=C(Nc1ccc(C(F)(F)F)c(Cl)c1)N1CCC(F)(c2ncc(C(O)CO)cc2Cl)CC1 +O=C(c1ccc(OCCCN2CCC(NS(=O)(=O)c3cccc(Cl)c3)C2)cc1)C1CC1 +O=C(CN1CCCCC1)Nc1cccnc1C(=O)Nc1nccs1 +O=C(NCc1ccc(Cl)cc1Cl)c1ccc(=O)[nH]c1 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1sccc1CO)O2)C(C)=CC(C)(C)N3 +CCn1cc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2C)nc(N2CCOCC2)c1=O +COCCNc1cc(-n2c3c(c4cc(F)ccc42)C(=O)CCC3)ccc1C(N)=O +O=[N+]([O-])c1cccc(Nc2nc(N3CCN(CCO)CC3)nc3[nH]cnc23)c1 +CCOC(=O)CSCCNC(=O)c1sc(SC(C)C)c(C#N)c1-c1ccc(Cl)cc1 +CC(C)(C)c1cc(NC(=O)c2ccc(Cl)c(Nc3ncnc4cnc(N5CCOCC5)nc34)c2)no1 +CNC(=O)CNCCc1cccc(-c2cc3nc(NC)c4ncc(C)n4c3s2)c1 +Cc1ccc(COc2ccc3[nH]c(C4C(C(=O)O)C4(C)C)[n+](Cc4ccc(Br)cc4)c3c2)nc1 +COCC(=O)N1CCN(Cc2ccc3[nH]c(-c4cc5cc(-c6cn[nH]c6)ccc5[nH]c4=O)cc3c2)CC1 +CC(C)(Nc1nccc(-c2c[nH]c3ncccc23)n1)c1ccccc1 +CCOP(=O)(OCC)c1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(-c3ccc(O)cc3)sc2c1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(Oc3ccccn3)cc2n1Cc1ccccn1 +COc1cccc(C#Cc2nn(C3CCN(C(=O)C=CCN(C)C)C3)c3ncnc(N)c23)c1 +CC1CN(c2nsc3ccccc23)CCN1CCCCN1C(=O)CC2(CCCC2)CC1=O +OCCCc1cc(F)c(OCc2c(-c3ccc(Cl)cc3F)nsc2C(F)(F)F)c(F)c1 +OC1CNC(CNC(COCOc2ccc(F)cc2)c2ccccc2)C1O +O=C(Nc1ccc(N(CCCl)CCCl)cc1)Nc1ccc2ncnc(Nc3ccc(F)cc3)c2c1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cc(F)ccc2F)CC1 +CCCC1(CC(=O)O)c2ccc(Cl)cc2-c2nc(O)c(O)nc21 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3c(C(=O)O)ccnc3c2)cc1 +CCCN(CCCCCCN(CCC)C1CCc2c(O)cccc2C1)C1CCc2c(O)cccc2C1 +Cc1cccc(-c2nc(C3CCN(Cc4ccc(-c5nc6nccn6cc5-c5ccc(F)cc5)cc4)CC3)n[nH]2)n1 +CC(C)c1ccccc1SC1=C(O)OC(CCCC(=O)N2CCSCC2)(c2ccccc2)CC1=O +CONC(=O)c1cc(Nc2ncnn3cc(-c4noc(C)n4)c(C(C)C)c23)c(F)cc1F +CCOC(=O)c1c(CN2CCN(CC#N)CC2)n(Cc2ccccc2)c2cc(Br)c(O)cc12 +Cn1cc(-c2ccc(C(=O)N3N=C(c4cccnc4)CC3c3c(O)cccc3F)s2)cn1 +Cc1cc(CNC(=O)c2sc3nc(C)c(Cl)c(C)c3c2N)ccn1 +CN(Cc1ccccc1)C(=O)C(Cc1ccccc1)NC(=O)C1CC(O)CN1C(=O)CCCc1ccccc1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CC4C(N)C4C3)cc2F)cn1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ncc(-c2ncccc2C(F)(F)F)cn1 +CC(CCC(=O)O)(NC(=O)NC(C)(CCC(=O)O)C(=O)O)C(=O)O +Cn1ccc2c3c(ccc21)CCN3C(=O)Nc1cccnc1 +C#Cc1ccc2nc(S)n3c2c1CN(CC=C(C)C)C(C)C3 +CCOc1ccc(C(=O)O)cc1NC(=O)C=Cc1ccc(-c2ccccc2)cc1 +CN(CC(=O)N1CCN(C(=O)c2ccccc2)CC1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +CC(C)CCNCCN1CN(c2ccccc2)C2(CCN(C3CCC(C)(C)c4ccccc43)CC2)C1=O +COc1cc(C=Cc2cc(-c3ccc(O)c(OC)c3)[nH]n2)ccc1O +CC(=O)N1CCN(c2nc(-c3ccc(Sc4ccccc4C(C)C)c(C(F)(F)F)c3)co2)CC1 +O=C(Cn1ccnc1[N+](=O)[O-])Nc1ccc(Oc2ccccc2)cc1 +NC(=O)n1cc(NC(=O)N2CC(F)CC2C(=O)NCc2cc(N3CCOCC3)cc(Cl)c2F)c2ccccc21 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCn1cccn1 +COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CC4CN(S(C)(=O)=O)CC4C3)cc12 +c1cc(CCc2cccc(-c3nn[nH]n3)c2)cc(OCc2ccc3ccccc3n2)c1 +COc1ccccc1N1CCN(CCC(O)c2ccc3ccccc3c2)CC1 +O=C(c1cc(Br)ccc1NS(=O)(=O)c1cccc2nsnc12)N1CCCCC1 +CCOC(=O)C(CC1CCCCC1)NC(=O)C(CC(C)C)NC(=O)Cc1ccccc1 +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OC[Si](C)(C)c2ccc(C)cc2)c1 +O=c1c(-c2ccc(OC(F)(F)F)cc2)cccn1C(CN1CCCC1)c1ccccc1 +CC(=O)Nc1cc(N)c(C#N)c(-c2ccccc2)n1 +CC(C)n1cc(-c2cnc(N)c(-c3ccc(C(=O)NC(CO)c4cccc(S(C)(=O)=O)c4)c(F)c3)c2)cn1 +Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccc(C(=O)N5CCOCC5)cc4)cc3s2)S(C)(=O)=O)o1 +CCc1c(C(=O)C(N)=O)c2cc(OCCC(=O)O)ccn2c1Cc1ccccc1-c1ccccc1 +CCCCOc1ccc2c(c1)C(c1ccc3c(c1)OCO3)=C(C(=O)O)C(c1ccccc1OC)O2 +CS(=O)(=O)c1ccc(CNC(=O)c2cc(N)c(C#N)c(-c3ccc(C(=O)O)s3)n2)cc1 +NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1ccccc1 +COCCc1ccccc1-c1ccc(C(CN)Cc2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)c(C)c1 +Cc1cc(C)c2c(c1)c(-c1ccccc1)c(-c1ccccc1)n2CC(O)Cn1cnc(-c2ccccc2)c1-c1ccccc1 +Cc1cc(C=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)no1 +COCCCn1cc(-c2cc(-c3cc4ccccc4s3)c3[nH]ncc3c2)c2nc(N)ncc21 +CC1CCCN1C1CCC(c2ccc(N3CCC4(CCOCC4)C3=O)cc2)C1 +Cc1ccc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C#N)CC3)n2)cc1F +CCCN1CCc2cccc3c2C1Cc1ccc(OS(=O)(=O)C(F)(F)F)c(OC)c1-3 +CC(C)(NP(=O)(OCC1C=CC(n2cnc3c(N)ncnc32)C1)Oc1ccccc1)C(=O)O +CN(C)CC1CCc2cc(NC(=O)c3ccc(-c4ccccc4)cc3)ccc2C1 +Nc1nc2c(Cc3ccccn3)c[nH]c2c(=O)[nH]1 +CN(CCOc1ccc(CC2SC(=O)NC2=O)cc1)C(=O)CCCCC(CCSC(=O)CN)SC(=O)CN 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+O=C(C1CCN(c2ccncc2)CC1)N1CCC(CNS(=O)(=O)C=Cc2ccc(Br)s2)C1 +O=[N+]([O-])c1cc([N+](=O)[O-])c(-c2cc[nH]n2)s1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)ncnc2cc1OCCN1CCC(=O)CC1 +COc1cc(Nc2ncc3ccn(-c4cccc(CCC#N)c4)c3n2)cc(OC)c1OC +CCc1cc(Nc2cc(=O)n(CCCO)c(=O)[nH]2)ccc1C +Cc1c(F)cccc1Cc1c(C(=O)N2CCNCC2)c2ncccc2n1-c1ccccc1 +COC(=O)C(N)CSC(c1ccccc1)(c1ccccc1)c1ccc(OC)cc1 +CCCCCCCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +NCc1cc(Cc2c(-c3ccc(OCCN4CCCC4)cc3)sc3cc(O)ccc23)ccc1CN1CCCC1 +Nc1nc2ccccc2n2c(=O)c(-c3ccc(F)cc3)nn12 +Cc1[nH]c(C=C2C(=O)Nc3ccccc32)c(C)c1CCC(=O)O +CC(=O)N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +Cc1ccc(F)c(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1Cl +CC(C)(C)C1CCN(C(=O)n2ncc(C(O)(c3ccccc3)c3ccccc3)n2)CC1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cnn(CC4CCCOC4)c3)c(C(=O)O)n1)CC2 +CNc1nc(NC2(C#N)CCCC(C)C2)nc(-n2cncn2)n1 +CN(Cc1ccccn1)C(=O)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)CCC4 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)NCc3cccnc3)[nH]c12 +O=C(Nc1ccccc1)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccccc1 +Cn1nc2c(c1-c1ccccc1)-c1nc(Nc3ccn(CCN4CCCC4)n3)ncc1CC2 +Cc1cc(-c2nc(-c3ccc(OCC4COC(=O)N4)c(C)n3)no2)cc(CC(C)C)n1 +COc1ccc(C2=NN(CCn3ccnc3)C(=O)C3CCCCC23)cc1OC +NS(=O)(=O)OCC1OC(OCC2C(CO)OC(O)C(O)C2O)C(O)C(O)C1O +Cn1cc(-c2cn(-c3ccnc4c3c(C(F)(F)F)nn4-c3ccc(C(N)=O)cc3N)cn2)cn1 +COc1ccc2c(c1)cc(-c1ccccc1)n2Cc1csc(C(=O)O)n1 +COc1cc2c(c(OC)c1)CN1CCc3cc(OC)c(O)cc3C1C2 +Nc1nc(-c2cccc(CN3CCC(c4ccccc4)CC3)c2)cc2nc(-c3ccco3)nn12 +CS(=O)(=O)c1ccc(C(=O)N2CCN(c3ccc(OC4CCN(C5CCCC5)CC4)cc3)C(=O)C2)cc1 +CC(C)N1CC(C(=O)N2CCN(c3ccccc3Cn3cnnc3)CC2)C(c2ccc(Cl)cc2)C1 +CSc1ccc(-c2ccc(C(=O)CC(=O)C(=O)O)cc2)cc1 +COc1cccc(F)c1C1CC(C)C(=O)N1Cc1cccc(-c2nc(Cl)cs2)c1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ccc(OCC(F)F)cn3)cs2)CO1 +CC1(N)CCC(Nc2c(C(N)=O)cnn3cc(-c4ccc(Cl)cc4)cc23)C1(C)C +CC(C)(Cc1ccc2ccccc2c1)NCC(O)C1CCCN1Cc1cccc(C#N)c1 +O=C(c1nn(C2CCCN(CCN3CCOCC3)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +NC1=NCCCN1Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 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+NC(=O)n1cc(NC(=O)N2CCC(N)C2C(=O)NC(c2cccc(Cl)c2F)C(F)(F)F)c2ccccc21 +CCCCN(Cc1cncn1Cc1ccc(C#N)cc1)c1ccc(Oc2ccccc2)cc1 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)c2ccccc2C)cc1 +CCCC1(C)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21 +NC1CCCC(c2ccncc2NC(=O)c2ccc(F)c(-c3cc(F)ccc3F)n2)C1 +CC(C)(C)C(=O)Nc1ccc(N=Nc2ccccc2)cc1 +NC(CC(=O)N1CCC2C(CCc3nnc(-c4ccccn4)n32)C1)Cc1cc(F)c(F)cc1F +CC(C)(C)c1ccc(OS(N)(=O)=O)c(OS(N)(=O)=O)c1 +COCCc1nccn1CC1CC(c2ccccc2)(c2ccccc2)C(=O)O1 +CCCCCCCCCCCCCCCCCCN1CCN(C(=O)Nc2ccc(Cc3noc(=O)[nH]3)cc2)CC1 +N#Cc1ccccc1CSc1nnc2c3ccccc3n(C(=O)c3ccc(F)cc3)c2n1 +O=C1CCC2(O)C3CC4=C(CCCC4)C2(CCN3CC2CC2)C1 +CC(Nc1ncnc2[nH]cnc12)c1nc2ccccc2c(=O)n1-c1cccc(F)c1 +CC(=O)Nc1ccc2c3c(n(CCCCl)c(=O)c2c1)-c1cc2c(cc1C3=O)OCO2 +CCOC(=O)C1(Cc2ccccc2)CCCc2cnc3c(-c4ccc(C(F)(F)F)cc4)cnn3c21 +CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)cc3)CC2)nc1C(F)(F)F +O=C(CO)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)Cc1c(F)cccc1F 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+CCN(C(=O)CO)C1CN(C(=NC#N)Nc2cccc(OC(F)F)n2)N=C1c1ccc(Cl)c(Cl)c1 +O=C(CNC(=O)C1(CS)CCc2ccccc2C1)OCc1ccccc1 +CCOC(=O)CN1Cc2cc(OCCCC(=O)N(C)C3CCCCC3)ccc2N=C1N +O=C(NCC1(CO)CCCCC1)c1nc2c(-c3ccccc3)cccc2[nH]1 +CC12Nc3ccccc3C1(O)CCN2Cc1ccc(C=CC(=O)NO)cc1 +O=C(NCc1cccc(OCCOc2nc[nH]n2)c1)c1nc2scc(-c3ccccc3F)c2c(=O)[nH]1 +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 +O=C1Nc2c(Cl)cccc2C1=CNCCCNc1ccnc2cc(Cl)ccc12 +CN1CCCC(NC(=O)c2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c2)C1 +COc1cc(OC)cc(N(CCO)c2ccc3ncc(-c4cnn(C5CCN(C(=O)OC(C)(C)C)CC5)c4)nc3c2)c1 +O=C(O)CC(Cc1ccc(OCCCNc2ccccn2)cc1)c1ccccc1 +N#Cc1ccc(NC(=S)NC(=N)Cc2ccc(Cl)cc2)cc1 +O=C(NO)C(CNS(=O)(=O)c1ccc(OCc2ccc3ccccc3c2)cc1)N1CCCCC1 +CS(=O)(=O)Nc1ccc(-c2coc3cc(C#CC4CN(C(=O)C5CC5)C4)ccc3c2=O)cc1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2ccccc2-c2ccon2)n1 +CCC(=O)Oc1ccc(-c2nc(-c3cccnc3)no2)cc1 +CC(=O)N1CCCN(C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +Cc1csc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)n(C)c2=O)n1 +c1cc(C[n+]2ccc(N3CCCC3)cc2)ccc1CCCc1ccc(C[n+]2ccc(N3CCCC3)cc2)cc1 +CN(C)CC(=O)Nc1ccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)cc1 +CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NCCc3ccccc3)CC2)nc1C(F)(F)F +CCc1nc(-c2ccc(-c3ccc(CCC(N)(CO)COP(=O)(O)O)cc3)cc2)co1 +Cc1cc(CC2CC2)cc(C)c1NC(=O)Nc1cc(F)ccc1C(=O)NC(C(=O)O)C(C)OC(C)(C)C +CN(C)CCCN(C(=O)c1ccc2c(c1)sc1c(O)nc3ccccc3c12)c1ccccc1 +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1cccc(OC(F)(F)F)c1 +O=C(c1cccc(O)c1)c1ccc(-c2cccc(NS(=O)(=O)c3ccc([N+](=O)[O-])cc3)c2)s1 +Cn1c(=O)c(-c2c(F)cccc2F)cc2c(N)nc(Nc3ccccc3)nc21 +Clc1cccc(Nc2[nH]nc3ncnc(NCc4ccccc4)c23)c1 +Cc1cccc(C(CC2CCCCC2)Nc2nc3ccccc3o2)c1 +CN(C(=O)C1CC1)c1ccc2c(c1)nc(NC(=O)c1ccc(C#N)cc1)n2CCC(N)=O +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)C3CCC3)c3ccccc32)CC1 +Nc1nc(N)c2c(n1)CCC2CCc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +O=C(c1nn(-c2ccccc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1)N1CCCCC1 +Cc1cc(-c2nc3cnc(N4CCOCC4C)nc3n2C(C)c2ccccc2)cn(C)c1=O +CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3ccc(Br)cc3F)c2c1 +O=C(c1cccc(C(F)(F)F)c1F)N1CCc2c(nnn2-c2ccccn2)C1 +CC1CC2CC(c3cccc(O)c3)(CCN2CCc2ccccc2)C1 +COc1ccc(C(Cc2ccncc2)c2cccc(F)c2)cc1OC1CCCC1 +CCN1C(=O)Cn2c1nc1nc(N3CCCC(N)C3)n(Cc3cc(F)ccc3C#N)c1c2=O +Cc1ccccc1NS(=O)(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COc1ccccc1C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1 +CC(C)c1cc(-c2cccc(C=C(C(=O)O)c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1 +O=C(Nc1ccc(-c2ccccc2)cc1)Nc1ccc2c(c1)NC(=O)C2=Cc1ccc[nH]1 +COc1cc(C=Cc2ccc(CCC(=O)C(C)(C)C)cc2)cc(OC)c1 +CN1C2CCC1CC(OC(c1ccc(F)cc1)c1cccc(Br)c1)C2 +COc1cc(C=Cc2ccc(N(C)C)cc2)cc(OC)c1OC +CCOC(=O)c1ccc2ncnc(NCc3ccc4c(c3)OCO4)c2c1 +CN(C(=O)C1=Cc2cc(Br)ccc2S1(=O)=O)c1ccccc1 +CNC(=O)c1ccc(-c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C)cc3)n2)cc1 +Cc1c(Oc2cnc(C(=O)N3CCC(C)(O)C3)cn2)ccc2c1B(O)OC2 +CC(C)Nc1nc(-c2ccc(N3CCCC3)c(S(C)(=O)=O)c2)cc2ncn(C)c(=O)c12 +O=C1C2C3CCC(C4CC43)C2C(=O)N1CCCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +O=C(O)CON=Cc1nc2ccccc2n1C1CC2CCCC(C1)N2C1CC2CCCC(C2)C1 +CCOc1ccc(-n2c(C(C)N(Cc3cccnc3)C(=O)Cc3ccc(S(C)(=O)=O)cc3)nc3ccccc3c2=O)cc1 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+S=C(Nc1ccc(Cl)cc1)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +O=C(c1ccc(Nc2nccc(-c3cc4ccccc4s3)n2)cc1)N1CCC(N2CCCC2)CC1 +N#CC1CCN(C(=O)OCC2CC2)CC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +Cc1cn2nc(C3CCCCN3C(=O)c3cc(Cl)ccc3NS(C)(=O)=O)cc2nc1N1CCC(O)C1 +O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1nc(N2CCNCC2)nc2ccccc12 +CC(C)C1(CNS(=O)(=O)C(F)(F)F)CCN(S(=O)(=O)c2ccc(Cl)cc2S(=O)(=O)c2ccccc2F)CC1 +N=C(N)c1ccc2[nH]cc(CC(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cn3)c2c1 +C#CC(=O)Nc1cc(-c2cnc3[nH]cc(C)c3c2)ccc1F +CC(C)c1cc(Nc2cc(OC3CCN(C)C3)nc(NCc3cc(C(C)C)no3)n2)[nH]n1 +N#CC(c1cccnc1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1 +COCCN1CCCC1Cc1c[nH]c2ccc(-n3cnc4cc(C#N)ccc43)cc12 +Fc1cccc2nc(N3CCN(Cc4cccs4)CC3)c3cccn3c12 +CC(C)(C)C(=O)NCCC1(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)CCCC1 +Cc1cc(-c2nc(C(c3ccc(F)cc3)c3ccc(F)cc3)sc2CC(=O)O)cnc1N +O=C(O)c1ccc2nc(C(=O)COc3ccc(SCCCCCc4ccccc4)cc3)sc2c1 +CC(C)n1ncc2c(C(=O)Nc3ncccn3)cc(-c3cccs3)nc21 +COCC1CCCN1c1cccc(Nc2cc(-c3ccccc3)nn3ccnc23)n1 +CN(C)CCCNCc1cccc(-c2cc(NCCN3CCOCC3)c3ccccc3n2)c1 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+CN1CCc2c3c(n(-c4ccc5c(c4)CCNC5=O)c2C1)CC(C)(C)CC3=O +COc1cc(-c2ccc3ncnc(Nc4cc(O)c(Cl)cc4Cl)c3c2)ccc1O +COc1cc(C(=O)c2csc(-c3ccccc3)n2)cc(OC)c1OCCN +CC1(C(=O)NC(CC(=O)O)c2ccc(-c3c(O)cccc3O)cc2)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +O=C(CSc1nnc(-c2ccc(O)cc2)[nH]1)Nc1ccccc1Cl +COC(=O)C=Cc1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(Cl)c(Cl)c1 +CCNc1nc2cnccc2nc1N1CCC(Oc2ccc(OC)cc2F)CC1 +Cc1cc(C=CC#N)cc(C)c1Nc1ccc(F)c(Nc2ccc(F)cc2)n1 +CCOC(=O)c1cc2c(n1C)-c1nc(Nc3ccccc3)ncc1CCC2 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(Cc1ccccc1)C(C)(O)C(=O)NO +N#Cc1ccc(-c2ccc(C(CCNC3CCCC3)CNC(=O)Nc3cc(Cl)cc(Cl)c3)cc2)cc1 +O=C(c1ccc(Cl)cc1C(F)(F)F)N1CCn2c(nnc2-c2cnccn2)C1 +CN1CCN(C23CCNC(C(c4ccccc4)C2)C(c2ccccc2)C3)CC1 +O=C1C(=Cc2c[nH]c3ccccc23)Oc2c1ccc(O)c2CN1CCCNCC1 +CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc(-c4ccc(CO)cc4)cc3)cc12 +CCCCCCC=C1CC(CO)(COC(=O)c2ccccc2C)OC1=O +CN(C)CCCn1cnnc1-c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)cc3Cl)cc2F)ccn1 +COc1cc(C=NNC(=O)C(OC)c2ccc(N3CCOCC3)cc2)cc(OC)c1Br +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1cccc2ccccc12 +Cc1nc(O)c2cc(-c3ccc4c(c3)OCO4)c(C(C)C)cc2n1 +O=C(NS(=O)(=O)NCC1OC(n2cnc3c(NC4CC4)ncnc32)C(O)C1O)c1ccccc1O +CC1CCC(Cn2c(N3CCOC4CCCC43)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cc(Cl)cnc4OCCO)c32)CC1 +COc1ccccc1Oc1cccc(CN2CCC3(CC2)CCN(C(=O)c2ccc(Cl)cc2)CC3)c1 +OCCCCCN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +O=C(NC1CN2CCC1CC2)c1ccc2cc[nH]c2c1 +CC(NC(=O)Nc1cc2[nH]nc(C#N)c2cn1)c1ccccc1 +Cc1ccc(CNCC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)o1 +CN(Cc1ccc(Cl)cc1)C(=O)n1cnc(S(=O)(=O)C2CC3CCC2C3)n1 +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=NC#N)c(F)c2)cn1C(C)C +OC(c1ccc(Cl)cc1)(c1cccnc1)c1ccc(F)cc1F +CC(C)c1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)ccnc21 +Cc1cc(C)c2oc(Nc3ccc(-c4cccc(C(N)=O)c4N)cc3F)nc2c1 +CCNC(=O)C1OC(n2cnc3c(N)nc(C#Cc4ccc(C(C)=O)cc4)nc32)C(O)C1O +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4cccc(Cl)n4)c3)ncnc12 +COc1cccc(-c2cc3[nH]c4ccc(O)cc4c3c3c2C(=O)NC3=O)c1 +CCC(C)C(=O)NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1 +N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccsc1 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+O=C(NCC1CCOCC1)c1cnc(Nc2cccc(Cl)c2)cc1C1CC1 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cccc(OC(F)(F)F)c3)c(F)c2)CC1 +Cc1cc(SCc2csnc2-c2ccc(C(F)(F)F)cc2)ccc1OCC(=O)O +O=C(NC(C(=O)N1CCCCC1)=C(Br)c1ccccc1)c1ccc(Cl)cc1 +CC(C)(C)c1ccc(-n2nc(-c3ccncc3)cc2CCCCC(=O)NC(CC(N)=O)Cc2ccccc2)cc1 +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCCC4)c23)c1 +CN1CCC(CNC(=O)Nc2cc(Cl)cc(Cl)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +CCc1ccccc1-n1nc(C)cc1Oc1ccccc1NC(=O)Nc1ccc(C(C)C)cc1 +O=C1NC(Nc2ccc3c(c2)OCO3)=NC1=Cc1ccc2c(c1)OCO2 +CN1C(=O)NCc2c(NC(=O)NC3CC(C)(CF)Oc4cc(Cl)ccc43)cccc21 +COc1ccc(C=NN(C)c2ncnc3ccccc23)cc1OC +CN1C(=O)CCc2cc(-c3cccnc3)c(OCc3ccccc3)cc21 +Cn1cnc(S(=O)(=O)N2CC3C(C2)C3(CNC(=O)c2ccc(Cl)cc2)CC2CC2)c1 +COc1ccc(C2(Cc3ccncc3)CCN(S(=O)(=O)c3ccc(C)cc3)C2=O)cc1OC1CCCC1 +O=C1CCc2ccc(OCCCCN3CCN(c4ccc(O)c5[nH]c(=O)ccc45)CC3)cc2N1 +CCn1c2ccccc2c2cc(NS(=O)(=O)c3c(OC)ccnc3OC)ccc21 +c1cc(-c2cnc3[nH]cc(-c4cn[nH]c4)c3n2)ccn1 +CCOc1ccccc1N1CCN(CC(O)CN2C(=O)NC(=Cc3ccc(Cl)cc3)C2=O)CC1 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+COc1cc2c(NC3CCCCC3)c(C(N)=O)cnc2cc1-c1c(C)noc1C +ON=c1cc(-c2cc3cccn3cn2)oc2ccc(OCCCc3cccnc3)cc12 +COc1cc(-c2ncc(-c3ccc(N4CCNCC4)nc3)n3cc(C=Cc4ccc5ccccc5n4)nc23)ccn1 +CC(C)N(CCN1CCOCC1)C(=O)C(C)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O +O=C(NC(Cc1c[nH]c2ccccc12)C1CN=C(CCc2ccccc2)S1)OC1C2CC3CC(C2)CC1C3 +CC1(C)CC=C(c2cc(C(O)C(=O)O)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +CC(=O)OC1(C)c2ccccc2-c2c1c(-n1ccnc1)nc1ccc(Br)cc21 +CC1CCCCN1c1cccc(-c2c[nH]c3ccc(-c4nnc(N)s4)cc23)n1 +CCC1(C)Cc2cccc(OCCNCc3cccc(C4=CCCC4)c3)c2O1 +COc1ccccc1N1CCN(CCCCc2ccc3nc(O)sc3c2)CC1 +CCCOc1ccc(NCc2cnc3nc(N)nc(N)c3c2C)cc1OC +CN(CCCN)C(=O)N1CC(c2cc(F)ccc2F)=CC1c1ccccc1 +NC(=O)c1ccc(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)cc1 +CCOc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cc1Cl +CC(C)CN(Cc1ccc(N2CCC(N(C)C)C2)cc1)S(=O)(=O)Cc1ccccc1 +O=C(Nc1ccc(N2CCOCC2)cc1)C(=O)c1c[nH]c2c(Cl)cccc12 +CCC(Sc1nc(-c2cccc(OC)c2)c(C#N)c(=O)[nH]1)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 +CCCCCCSc1cc(C)c(C(=O)CCN2CCN(C(C)=O)CC2)c(C)c1 +Fc1ccc(C23CCN(CC2)Cc2cc(Oc4ccc(C(F)(F)F)nn4)ccc23)cc1 +Cc1nc2c3ccccc3nc(SCc3ccc4ccccc4n3)n2n1 +CC1CCC2C(C)C(OC(=O)CCN3CCN(C)CC3)OC3OC4(C)CCC1C32OO4 +CCCCc1nnc(S(C)(=O)=O)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +CC(NC(=O)C1(N)CCN(c2ncnc3[nH]ccc23)CC1)c1ccc(F)cc1 +O=C(c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1)N1CC(F)CC1c1cc(F)ccc1F +Cn1c(NC(C)(C)C)nc2c(-c3cc4c([nH]3)CCNC4=O)cccc2c1=O +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1-c1ccc(=O)n(C)c1 +COc1ccc(CCN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1 +Cc1cc(Oc2nccc3[nH]ccc23)ccc1-c1c(C)n[nH]c(=O)c1C +CCCCCCCCCCc1ccc2c(c1)N(C)C(C(C)C)C(=O)NC(CO)C2 +COc1ccccc1CCc1nnc(-c2ccc3[nH]cnc3c2)s1 +Fc1ccc(Cn2c(C3CCCNC3)nc3ccccc32)cc1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1ccc(CN2CCC(F)(F)CC2)c(F)c1 +COc1ccc(-c2nc(N)c(CN)c(-c3ccc(Cl)cc3Cl)n2)cc1 +N#Cc1cc(COc2ccc3[nH]c4c(c3c2)CCC4CC(=O)O)cc(OC(F)(F)F)c1 +Cc1ccc2[nH]c(-c3ccc(S(N)(=O)=O)cc3)c(-c3ccccc3)c2c1 +NCCN1CCCC(NC(=O)N2CCC3C2C(=O)N3S(=O)(=O)O)CC1 +Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(C(F)(F)F)c2)c(=O)c2ccc(CO)cc21 +O=c1cc(-c2ccncc2)[nH]n1-c1ccc([N+](=O)[O-])cc1 +Cc1cc2c(o1)-c1c(c3ccccc3c(=O)n1CCCN1CCC(N3CCOCC3)CC1)C(=O)C2=O +Cc1cc(NCc2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)on1 +COc1nc(N2CC3C(=O)N(C)C(N)=NC3(c3c(F)cc(F)c(F)c3F)C2)nc(C)c1F +Cc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1ccccc1 +Cc1c(CN2CCC(C(=O)NC(C)(C)C)CC2)cccc1NC(=O)c1ccc(F)cc1 +Cc1ccccc1CNc1c2c(nc3ccccc13)CCCC2O +CC(=O)Nc1cc(-c2cccc(OC3CCN(C)C3)c2)nc(-n2nc(C)cc2C)n1 +O=C(Nc1cccc(C(=O)c2ccc3c(C=Nn4cnnc4)n[nH]c3c2)c1)c1ccccc1 +CCCNc1cc2[nH]c(=O)cc(C(F)(F)F)c2cc1C +COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(C)(F)F)cc1 +CCN1C(=Cc2sc3ccc(O)cc3[n+]2CC)C=Cc2ccccc21 +CCN1CCC(NC(=O)c2ccc(Nc3ncc4c(n3)-c3c(nn(C)c3-c3ccccc3)CC4)c(OC)c2)CC1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)Oc1ccc(F)c2ccccc12 +CNc1nn2c(C)c(CCN)c(C)nc2c1S(=O)(=O)c1ccccc1 +N#Cc1c[nH]c(C(=O)Nc2ccc(-c3nnn[nH]3)cc2C2=CCCCC2)n1 +O=C(CCCN1CCN(CC(=O)c2ccccc2)CC1)NC1c2ccccc2CSc2ccccc21 +Cc1nc2ccccc2n1Cc1ccc(CNC(=O)C(O)C(O)C(=O)N2CCCC2c2ccccn2)s1 +Cc1cc(NC(=O)C(=O)c2cn(Cc3cc(-c4ccccc4)no3)c3ccccc23)sn1 +Nc1ccc(OCC(O)CNCCc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)cn1 +O=C(NC1CCCCC1)N1CCN(C(c2ccc(Cl)cc2)c2ccccc2C(F)(F)F)CC1 +O=C(CN1CCCC(c2nc3cc(Cl)c(Cl)cc3[nH]2)C1)c1cc(Cl)cc(Cl)c1 +CCOc1ccc(C(C)=O)cc1NC(=O)c1cc(C(=O)O)cc(-c2ccoc2)c1 +CCOc1ccc(-c2c3c(c(O)c4ncccc24)C(=O)N(Cc2ccc(F)cc2)C3)cc1 +CC(C)CN(NC(=O)c1cncc(-c2ccc(CN3CCN(C)CC3)cc2)c1)c1nc(C#N)ncc1Br +COc1ccc(CNC(=O)CCC(=O)N2CC3CC(C2)c2cccc(=O)n2C3)cc1 +CN1CCC(c2c[nH]c3ccc(NC(=O)c4ccco4)nc23)CC1 +CC(=O)Nc1ccc(-c2nc(-c3nnc(Cc4ccc(F)cc4)o3)c(O)c3ncccc23)cc1 +O=C1CC(c2ccccc2)Cc2c1c1c(n2CCc2ccccc2)-c2ccccc2C1=O +O=C(O)COc1ccc(CCN(C(=O)c2ccccc2)c2ccc(Cl)cc2)cc1 +CC(C)Cc1ccc(Nc2nc(=O)n(CCO)c(=O)n2Cc2ccc(Cl)cc2)cc1 +CC(COc1c(-c2ccccc2)c(O)nc2cc(Cl)ccc12)=NO +CCc1nc(N)nc(N)c1C#CC(C)c1cnc(-c2ccccc2)nc1 +FC(F)(F)c1cccnc1N1CCc2nc(C3CC3)nc(Nc3ccc(Cl)cc3)c2CC1 +CCn1cc(-c2cccc(-c3cnc(N)c(C(=O)NC4C5CC6CC4CC(O)(C6)C5)n3)c2)cn1 +COCC1CC2CCC(C1)N2c1nc(C#N)nc2scc(-c3ccccc3OC)c12 +CCCCCOc1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +CC(O)c1cc(C(=O)NC(C)c2ccc(F)cc2)ccc1-c1cn[nH]c1 +O=C(Nc1nc2cc(CN3CCCCC3)ccc2n1C1CCC(CO)CC1)c1cccc(C(F)(F)F)c1 +CCCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(ccc3ncccc23)C1 +C#CCN(Cc1ccccc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +CN1CC=CCOCc2cccc(c2)-c2ccnc(n2)Nc2cccc(c2)C1 +CCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2)cc1 +CC(NC(=O)c1ccon1)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 +CC(=O)NCC1CCCc2c1c1cc(OC(F)(F)F)ccc1n2C +O=C(Cn1ccc(C(F)(F)F)n1)N1CCN(c2scnc2-c2nc3ccccc3[nH]2)CC1 +COc1ccccc1N1CCN(CC(O)CCNC(=O)c2ccc(-c3ccccn3)cc2)CC1 +CCCSc1nc(N2CCOCC2)ncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 +COCC(C)NCc1csc(NC(=O)c2cc(Oc3ccc(S(C)(=O)=O)cc3)cc(-c3ncccc3C)c2)n1 +COc1cc(-c2ccccc2C)ccc1C(C)C#Cc1c(C)nc(N)nc1N +OC1c2ccc(F)cc2CC1N1CCN(c2cccc3c2OCCO3)CC1 +COc1ccccc1OCCN1CCN(c2ccc(=O)n(CCCCCCN3CCN(c4ccccc4Cl)CC3)n2)CC1 +COc1cc(C=CC(=O)c2ccc(OCCOC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)cc(OC)c1OC +N#Cc1ccc(Cn2cncc2CN2CCCN(C(=O)c3ccccc3F)CC2)cc1 +CN(C)C1CCN(CC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)CC1 +Cc1ccc(-c2ccc(S(=O)(=O)Nc3ccc4c(c3)CCN(C)CC4)cc2)s1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4ncc(=O)[nH]c34)cc2)cc1 +O=C1NC(c2cccc([N+](=O)[O-])c2)=CCN1c1ccccc1O +CS(=O)(=O)c1ccc(COc2ccc3c(c2)c(C#N)cn3-c2ccc(C(=O)O)cc2)cc1 +CCC(Nc1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)c1ccc(S(C)(=O)=O)cc1 +CCN(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccccn1 +Cc1nc(-c2ccc(N3C(=O)C(=O)C(S(=O)(=O)c4ccccc4)C3C3CCCCC3)cc2)no1 +O=c1c2ccccc2oc2ccc(OC3CN4CCC3CC4)cc12 +CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(CCI)C1CCC(CO)CC21 +COC1CN(C(=O)c2ccc(Nc3cc4c(-c5cnn(C)c5)cccc4cn3)c(Cl)c2)C1 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(C(F)(F)F)ccc1NC(C)C +CN(CCCNc1ccnc2cc(Cl)ccc12)Cc1ccc(-c2ccc(F)cc2)s1 +Cn1nc(C(C)(C)C)cc1C(=O)NC(Cc1cccc(-c2nnc(CCN)o2)c1)C(=O)NCC#N +CC(C)C(NC(=O)C(CC#Cc1ccccc1F)NCP(=O)(O)O)C(=O)O +CS(=O)(=O)c1ccc(-c2sc3ncnn3c2-c2ccc(F)cc2)cc1 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1ncnc2nn3ccccc3c12 +CC(C)(Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)Sc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 +O=C(NC1C2CC3CC(C2)CC1C3)C1SCCN1S(=O)(=O)c1ccccc1F +COC(=O)C(Cc1ccc(O)cc1)NC(=O)c1cc(C(=O)O)c2cc(-c3ccc(Cl)cc3)ccc2n1 +O=S(=O)(c1cc(Cl)cc(Cl)c1O)N1CCCC1c1nn[nH]n1 +N=C(N)c1cccc(OCC(NC(=O)c2ccc(-c3ccccc3S(N)(=O)=O)cc2)c2ccccc2)c1 +Cc1c(-c2cn(C3CCC3)cn2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +c1ccc(-n2cc(COCc3ccc(-c4nnc5n4-c4cccnc4Nc4ccccc4-5)cc3)nn2)cc1 +CCCC(CNC(=O)c1nc(Cl)c(N)nc1N)[N+](C)(C)C +COc1cc(C(=O)NC(CN)Cc2ccccc2)ccc1-c1cn[nH]c1 +CCS(=O)(=O)C(C(=O)NCc1nnc(C)o1)c1nc2cc(F)c(-c3ccccc3)cc2s1 +COc1cc2c(Oc3ccc(NC(=O)c4cn(-c5ccc(F)c(F)c5)nn4)cc3F)ccnc2cc1OCCCN1CCCCC1 +CN1CCc2ccc(Cc3ccc(O)c4ccccc34)c3c2C1Cc1ccc(O)c(O)c1-3 +COc1cc(C(=CC#N)c2ccc3c(c2)c(C#N)cn3C)cc(OC)c1OC +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1cc(CCN2CCCC2)cnc1C +O=C1N(Cc2ccc3[nH]ncc3c2)C(CCc2ccccc2)C(O)C(Cc2ccccc2)N1Cc1ccc2[nH]ncc2c1 +CN1CCN(c2nc(-c3ccc(Br)cc3)nnc2-c2ccccc2)CC1 +Cc1cc(C)c2c3c1C1C=CCC1CN3C(C(=O)O)C1CC=CC21 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+O=C(NC(Cc1ccccc1)C(=O)COCC(=O)N1CCCC1C(=O)O)c1ccccc1 +FC(F)(F)c1ccc(-c2nnc3ccc(NC4CCCCC4)nn23)cc1 +CCN(Cc1ccccc1)Cc1ccc(C(=O)c2ccc(OC)c(OC)c2)cc1 +Nc1ncnn2c(CN3CCNCC3)cc(-c3ccc(CO)cc3)c12 +Oc1nc(CNC2CCC(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)C2c2ccccc2)c[nH]1 +O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(Cl)c3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cc2C#N)c(F)c1 +CN(C)Cc1cccc2[nH]c(-c3nc(CCc4ccc(Cl)cc4)no3)cc12 +COc1cc(OC)cc(-c2cc3cnc(N(CCCOCc4ccccc4)C(C)=O)cc3nc2NC(=O)NC(C)(C)C)c1 +N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCCCCOc3cc4c(cc3C(=O)N2)CCCC4)CC1 +COc1ccc(CN)cc1NC(=O)CN1CCCCC(NC(=O)c2ccc(-c3ccccc3)cc2)C1=O +c1ccc(Oc2nc3ncnc-3c(NC3CCCCC3)[nH]2)cc1 +COC(=O)c1nn(C(=O)c2ccsc2)c2ccccc12 +O=S(=O)(c1ccc(Cl)c(Cl)c1)N1CCCc2ccc(Oc3cc(-c4nc(C5CC5)no4)cc(Cl)n3)cc21 +COc1c(C=Cc2ccc(NS(C)(=O)=O)c(F)c2)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C +CC(NC(=O)Cc1ccoc1)C(=O)NC1C(=O)N(C)N(C(C)C)C(=O)c2ccccc21 +O=C1c2c(F)cc(F)cc2CCC12CCN(CCc1ccccc1)CC2 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+N#Cc1cccc(-c2ccc(CN(CCN3CCCC3)C(=O)Nc3ccc(F)c(C(F)(F)F)c3)cc2)c1 +NC(Cc1ccccc1)c1nc2ccc(-c3cn[nH]c3)cc2c(=O)[nH]1 +COc1ccc(NC(=O)Nc2ccc(Oc3ncnc4cc(OC)c(OC)cc34)cc2)cc1 +CCCCCc1ccc(S(=O)(=O)NCCc2c(-c3cccc(C)c3)[nH]c3ccccc23)cc1 +O=C(NCc1cc(F)c(N2C3CCCC2CC3)c(F)c1)Nc1cccc2[nH]ncc12 +COc1ccccc1N1CCN(C(C)CN2C(=O)NC3c4ccccc4N(C)C3C2=O)CC1 +Cc1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Cl)cc2)c1 +CCN1CCC(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)C1 +CC(C)N1CCN(CCN2CCC(c3cn(-c4ccc(F)cc4)c4cc(F)ccc34)CC2)C1=O +Cc1nn(Cc2ccc(NC(=O)c3cc4ccccc4[nH]3)cc2)c(C)c1CC(=O)O +Nc1nc(-c2cccs2)nc2cn(-c3ccccc3)nc12 +COc1ccccc1N1CCN(CCCNC(=O)CN2CCCCC2=O)CC1 +CC(=O)c1cnc2ccc(-c3ccc4nc[nH]c4c3)cc2c1Nc1cnn(C2CCN(C)CC2)c1 +CCC1([N+]23CCC(CC2)C(OC(=O)C2(O)c4ccccc4-c4ccccc42)C3)c2ccsc21 +CCCCC1CCc2cc(C(=O)C(C)C)cc3c(CCN4CCN(c5cc(C)ccn5)CC4)c(C)n1c23 +Cc1cccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)n1 +Cc1nc(-c2ccc(C)s2)c(-c2ccc(S(N)(=O)=O)cc2)o1 +O=C1C(=Cc2ccncc2)C(c2ccccc2)n2cccc21 +Cc1nc2ccc(F)cc2n1C1CC2CCC(C1)N2CCC(NC(=O)c1ccc[n+]([O-])c1)c1cccc(F)c1 +COc1cc(C=CC(=O)Nc2ccccc2)ccc1OCCCCCCN1CCCCC1 +c1nc(NC2CCCCCC2)c2cc(OCCN3CCOCC3)ncc2n1 +CC(=C1C(=O)Nc2ccc(Cl)cc21)c1ccc(-c2cccc(C(=O)N3CCCN(C)CC3)c2)o1 +NCC1(O)CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1 +CC(C)CC1CN(c2cccc(C(=O)c3cccnc3N)n2)CCN1 +COc1cc(-c2cnc3cccc(-c4ccc(CC(=O)N5CCOCC5)cc4)c3n2)cc(OC)c1OC +O=C(c1ccccc1-c1ccc(F)cc1)N1CC2CN(c3cnc4ccccc4n3)CC2C1 +CCSC(=S)SCC(=O)c1ccc(CC(=O)NCc2ccccc2)s1 +O=S(=O)(c1ccc(OC(F)F)cc1)c1cc(Cl)c2oc3c(c2c1)CNCC3 +O=C1c2c(c(N3CCCS3(=O)=O)c3cccnc3c2O)CN1Cc1ccc(F)cc1 +CC(Nc1nccn2c(-c3ccc(O)cc3)cnc12)c1ccc(S(N)(=O)=O)cc1 +Clc1cccc(Cl)c1OCCNCCOc1ccccc1OCc1ccccc1 +CNc1ccc(C2Cc3c(cccc3C(F)(F)F)N(CCN(C)C)C(=O)C2C)cc1 +CCc1cc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)c(C(=O)O)c2)c2c(n1)CCCC2 +C=CCC(O)C(NC(C)=O)C1NC(C(=O)O)CC1C=CC +O=C(c1ccc(Cl)cc1Cl)N1CCn2c(nnc2-c2cnccn2)C1 +CC1(F)CCCC1Nc1c(C(N)=O)cnn2cc(-c3cncc4ccccc34)cc12 +C=CCNC(=O)c1c[n+]([O-])c2c(cnn2CCCCC)c1N +COCCn1cc(NC(=O)c2csc(-c3nncn3C(C)C)n2)cn1 +NC(=O)c1ccc(Oc2ccc(CNCCc3ccccc3)cc2)cc1 +CC(=O)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 +CSc1cccc(CN2CCCC(CO)(Cc3cccc(Cl)c3)C2)c1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(Cc4cccnc4)c4ccccc43)CC2)C(C)C)c1 +COc1ccc(C=CC(=O)Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)cc1 +CCCCC#Cc1nc(NCc2cccc(Br)c2)c2ncn(C3OCC(O)C3O)c2n1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(c2cccc(CF)n2)CC1 +CC(Oc1c(N)ncc2c(-c3ccncc3)coc12)c1c(Cl)ccc(F)c1Cl +Cc1ccc2[nH]cc(-c3csc(NC(=N)NCc4ccccc4)n3)c2c1 +N#CCC1COc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc2N1CC(F)(F)F +Cc1nc(N)nc2c1cc(-c1cnn(C)c1)c(=O)n2C1CCC(O)CC1 +CCOn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccnc3)cc21 +COc1ccc(C(C(F)(F)F)C(F)(F)F)cc1CNC1CCCNC1c1ccccc1 +O=C(Nc1ccn(COP(=O)(O)O)c(=O)c1)c1cc(C(F)(F)F)ccc1Oc1ccc(F)cc1 +CCCC(NC(=O)N1CCc2cnc(NC(C)CO)nc2C1)c1ccc(OC)c(F)c1 +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1Cc2cccn3ncc(c23)C1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4cccc(Cl)c4)nc31)C(O)C2O +O=C(Nc1cccc(Cl)c1)Nc1nc2nn(CCc3c(Br)cc(Br)cc3Br)cc2c2nc(-c3ccco3)nn12 +O=S(=O)(Cc1ccc(Cl)cc1)NCCCCc1c[nH]cn1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccccc3)nn21 +Cc1nc2c(OCC3CCCCC3)cccn2c1C(=O)NC(C)(CO)c1cccc(C(=O)O)c1 +CC(C)C(C(=O)NS(=O)(=O)c1ccccc1)N1C(=O)C(=Cc2ccc(-c3ccccc3)cc2)SC1=S +CCN1CC(Cl)=C(c2cn(S(=O)(=O)c3ccc(OC)cc3)c3ccc(OC)cc23)C1 +CCCC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3cccnc3)c3ccccc23)CC1 +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(CCC(=O)O)C(=O)O +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(-c2cnco2)cc1 +Cc1ccc(C(=O)NC2C3CC4CC(C3)CC2C4)cc1S(=O)(=O)N1CCOCC1 +COc1ccc(C(C)C(F)(F)F)cc1CNC1CCCNC1c1ccccc1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(C3CC(F)(F)C3)n2)cc1OC(F)F +CCc1nc2c(C(=O)NC3CCCCC3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(C(=O)NCCCCO)c2)n1 +COC1(c2cc(Sc3ccc(C(C)=NO)cc3)cc(F)c2C)CCOCC1 +C=CC(=O)Nc1cccc(N2C(=O)N(Cc3ccccc3)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +CCNC(=O)C1OC(n2cnc3c(N)nc(N4CCN(c5ccc(OCCOC)cc5)CC4)nc32)C(O)C1O +Cc1ccc(-n2nc(C3CCN(CC4CC4)CC3)cc2NC(=O)c2cnn3cccnc23)nc1 +CC1=C(C(=O)N2CCCC2c2cc(C)on2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CN1CC2CC1CN2c1ccc(-c2ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn23)c(F)c1F +COc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OC1COC2CCOC21 +Cc1ccc(-c2nnc(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)o2)cc1C +O=C(CC1COC1)NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1 +CCC(C)NS(=O)(=O)c1ccc(F)c(C(=O)NCc2ccc(F)c(F)c2)c1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(F)c(C)c3)nn21 +Cc1ccc(NC(=O)C2CCCCC2)cc1S(=O)(=O)N1CCOCC1 +CC(=O)c1cnc2cc(C)c(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1ccc(CN(C)C)cc1 +CCCNC(=O)c1nnsc1S(=O)(=O)c1ccc(Cl)cc1 +COc1cccc(Nc2cc(-c3cccc(-c4cccc(C(=O)NCCN(C)C)c4)c3)nc3c2C(=O)NCC3)c1 +Cc1nc(NC2CCCc3ccccc32)cc(-c2ccc(Cl)c(N)c2)n1 +S=c1[nH]c(=S)c2c3c(sc2[nH]1)CCCCC3 +C=CCN(CCN(Cc1cncn1C)c1ccc(C#N)cc1)S(=O)(=O)c1cn(C)cn1 +CC1CN(Cc2ccc(-c3ccccc3CN(C)C(=O)CS(=O)(=O)c3ccccc3)cc2)CC(C)N1 +CCCCCCCC(C)NC(=O)c1cc(O)c2cccc(NS(C)(=O)=O)c2n1 +CCCCNc1nc(NCCCC)nc(NCc2ccc(S(N)(=O)=O)cc2)n1 +CC(=O)N1Cc2ccccc2CC1CN1CCC2(CCc3ccccc32)CC1 +Cn1c(Cc2nc(N3CCOCC3)cc(=O)[nH]2)nc2cc(F)ccc21 +Cc1ncc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1-c1ccnc(N2CCOCC2)c1 +FC1(F)CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)CC1 +O=C(c1ccon1)N1CCC(O)(c2ccccc2)C2CCCCC21 +O=C(Nc1ncnc2oc(-c3ccc(F)cc3)cc12)C1CCCC1 +CCN1C(=Cc2sc3ccc(OC)cc3[n+]2CC)C=Cc2cc(OC)ccc21 +O=C(NCCCNC(=O)c1ccc(O)c(O)c1)c1ccc(O)c(O)c1 +CCC(Oc1cc(C)ccc1Cl)C(O)CN1CCC(n2c(O)nc3ccccc32)CC1 +CCCc1c(OCc2cccc(Oc3ncccc3-c3nn[nH]n3)c2)ccc(C(C)=O)c1O +CCCCN(CCN(C)CCc1ccc(O)c2[nH]c(=O)sc12)C(=O)CCOCCc1ccccc1 +C=C(C)c1ccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 +CCc1c(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(C)c3)no2)sc(C)c1CC(C)C +C=CC(OC)C(NC(C)=O)C1NC(C(=O)O)CC1C=CC +COc1ccc(CCn2c(=O)nc(NCCNC(=N)N)n(Cc3ccc(OC)cc3)c2=O)cc1 +N#CC1CSCN1C(=O)CN(N)C1CCN(CC(=O)Nc2ncccn2)CC1 +COC1CCC(Nc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1cccc(OCc2c(C#N)no[n+]2[O-])c1 +Cc1c(C(=O)NCCCN2CCN(c3cccc(Cl)c3)CC2)cc(-c2ccccc2)n1N1CCCCC1 +Cn1c(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)nnc1C1CCOCC1 +CC1OC(=O)C2CC3CCCCC3C(CCCN3CCOCC3)C12 +CC(C)Oc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)cc(OC(C)C)c1 +O=C1N(Cc2ccc3ccccc3c2)C(Cc2ccccc2)C(O)C(C(Br)Cc2ccccc2)N1Cc1ccc2ccccc2c1 +CCc1ncnc(NC(CC)c2ccc(Oc3ccc(F)cc3)cc2)c1Br +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3C4CCC(C4)C3N(Cc3ccco3)C1=O)N2 +COc1cccc(C=NNc2cc(C)nc(-c3ccccc3O)n2)c1O +N#Cc1ncc(F)c(N2CCC(S(=O)(=O)c3ccccc3C(F)(F)F)C2)n1 +NCc1cc(Cl)c(C(=O)Nc2ccnc(NC(=O)C3CC3)c2)c(Cl)c1 +CC(C)(C)COCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1 +COc1cccc(NC(=O)c2cc3c(s2)CCN(c2cccc(-c4nc5ccccc5n4C)c2)C3)c1 +CNC(=O)CNC(=O)C1CCCCN(C)C(=O)OCCCC(C(=O)NO)C(CC(C)C)C(=O)N1 +CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4ccc(F)cc4)ccc3Sc3ccc(N)cc3)ncnc2n1 +Cc1cc(N2C(=O)C3C4CCC(O4)C3C2=O)ccc1Cl +CC(Nc1cc(F)ccc1F)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +Cc1cnc(-c2c(-c3nc(C)n4ncnc(N5CCC5)c34)cnn2C)c(F)c1 +COc1ccc(-c2ocnc2C(=O)NCc2ccnc(C)c2)cc1Cl +CN(C1CCC(n2cc(C(N)=O)c(Nc3ccc(Cl)cc3)n2)C(C#N)C1)C(C)(C)C +CC(=O)Nc1cc2ncccc2cc1C=CC(=O)N1CCN(Cc2ccc(F)cc2)CC1C +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1ccccc1OC(F)(F)F +Cc1ccc(-c2cc(OCC(=O)O)ccc2Cl)c2c1CCN(C(=O)OCc1ccccc1)C2 +CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2ccc(C(C)C)cc2)CC1 +O=C1c2ccccc2CN1C1CCC(N2CCN(c3nsc4ccccc34)CC2)CC1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1C1CCOC1 +CCCCCCCCS(=O)(=O)Oc1ccc2c(C)c(C)c(=O)oc2c1 +O=C(NCC1(c2ccc(C(F)(F)F)nc2)CCC(F)(F)CC1)c1cccc(F)c1Cl +CCC(CSC(CCc1ccccc1-c1nn[nH]n1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O +c1cc(-c2n[nH]c3ccc(C4CC4)cc23)cc(N2CCOCC2)n1 +COc1cc(CN(CC(C)C)C2c3ccc(Cl)cc3CC2C(=O)O)ccc1OCCN1C(=O)CCC1=O +CCCN1CCC2(CC1)Oc1ccccc1C1CC(c3ccccc3Cl)=NN12 +N#Cc1nc(C(=O)NCC(=O)O)c(O)c2c1N(Cc1ccccc1)C(=O)CC2 +COc1ccc(-n2nc(C)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2F)cc1 +CC(=O)Nc1ccc2ccn(-c3cc(NCCCCO)n4ncc(C#N)c4n3)c2c1 +CCC1CCCC(C2(CC(=O)N3CCCCC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCCn1c(=O)c2nc(C=Cc3cccc(Cl)c3)[nH]c2n(CCC)c1=O +COC1CS(=O)(=O)c2cc(C(=O)N=C(N)N)c(C)cc21 +CC(CCc1ccccc1)Nc1c(F)c(Oc2cccc(C(=N)N)c2)nc(Oc2ccc(O)cc2C(=O)O)c1F +Cc1cc(Oc2nccc3[nH]ccc23)ccc1-c1cncc2nccn12 +CN1CC2(CNC(=O)c3c2[nH]c2c3CCc3cnc(-c4ccc(OCCN5CCOCC5)cc4)cc3-2)C1 +Cc1cc(C(N)=O)nn1-c1cccc(-c2ccccc2OCC(F)(F)F)c1 +CC1(C)Cc2cccc(N3CCN(CCc4ccc5c(c4)NC(=O)CO5)CC3)c2O1 +COC(=O)C1=C(CN2CCOCC2CCC(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Cl +COc1ccc2c(c1)c(C=C1C(=O)NN=C1c1cnns1)cn2C +N#Cc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1 +CCC1OCC(=O)C1NC(=O)C(CC1(C)CCCC1)NC(=O)c1ccc(NS(=O)(=O)c2nc(C)cs2)cc1 +CCc1ccc2c(c1)C1c3cc(O)c(O)cc3CCC1NC2 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(Br)cc1 +CC1(C(=O)OC2C[N+]3(CC=Cc4ccccc4)CCC2CC3)c2ccccc2-c2ccccc21 +Cc1cc(C)cc(-c2c(O)nc3cc(Cl)ccc3c2OCC2CCCNC2)c1 +Cc1cnc2nc1-c1ccnc(c1)OCCC=CCOCc1cc(ccc1OCCN1CCCC1)N2 +CC(=O)N1CCN(c2ccc(Nc3nccc(-c4sc(N)nc4C)n3)cc2)CC1 +CC1(N)CCC(Nc2c(C(N)=O)cnn3cc(-c4ccc(C(=O)NC5CC5)cc4)cc23)C1(C)C +Nc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3Cc3ccccc3)cc12 +CCCCC(C=NNC(=O)OC(C)C)NC(=O)OC(C)(C)C +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccc(-n4cccn4)cc3)o2)C(C)O)c(C)c1Cl +Cc1ccc(-c2c(O)nc3cc(Cl)cc(Cl)c3c2O)cc1 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+CC(Oc1cc(-n2cnc3ccc(OCC4CCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1C(F)(F)F +Nc1ncc(-c2ccncc2)nc1C(=O)Nc1ccccc1 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2cccc(C(F)(F)F)c2)c1)C(F)(F)F +Cc1c(OCCCCOc2cccc(F)c2F)ccc(C(=O)CC(C)C)c1O +COCCCn1c(CN2C(=O)C(=NOCCCN3CCCCC3)c3ccccc32)nc2ccccc21 +COc1ccccc1-c1ccc(CC(NC(=O)C2CCCN2)C(=O)O)cc1 +CC(NS(=O)(=O)c1cccs1)C(=O)NC1=NN=C(c2ccc(Cl)cc2)CS1 +Cc1cc2c(cc1C)C(=O)CC1(CCN(C(=O)c3cccc4cn[nH]c34)CC1)O2 +O=C(Nc1cccc(Cl)c1)c1cccnc1SCc1ccncc1 +CCc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)O)n2Cc1cc([N+](=O)[O-])ccc1F +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(OC)cc3OC)ncc2Br)c1 +COc1ccc(Nc2ncc(F)c(Nc3ccc(OC)cc3)n2)cc1 +CC(=O)OC1CC2CC3(CCC2(C)C2CCC4(C)C(C(C)CCC(=O)O)CCC4C12)OOC1(CCCCC1C)OO3 +CCCCOc1cc(N(CC)c2ccc(C(=O)O)cn2)ccc1C(C)C +O=C(O)CC1c2ccccc2C(=O)N(CC(=O)NCCCCNc2nc3ccccc3[nH]2)c2ccccc21 +CCOCC(=O)NC(C)C(=O)N1CCN(CCCOc2ccc(-c3noc(-c4ccccc4)n3)c(F)c2)CC1 +O=C(O)CCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21 +CC(C)Oc1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(Cl)c2F)C1 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+C=CC(=O)Nc1cc(Nc2nccc(-c3cn4c5c(cccc35)CCC4)n2)c(OC)cc1N1CCC(CN(C)C)C1 +COCC(C)Oc1cc(C#Cc2cccc(N(C)C)c2)cc(C(=O)Nc2ccn(C)n2)c1 +Cc1ncc([N+](=O)[O-])n1CCOC(c1ccccc1)c1ccccc1[N+](=O)[O-] +CCC(Nc1ncnc2[nH]cnc12)c1cc2ccccc2c(=O)n1-c1ccccc1 +Cc1cc(OCCC(C)O)cc(C)c1-c1ccc(F)c(COc2cc3c(cn2)C2C(C3)C2C(=O)O)c1 +Cc1cc(NCC(N)c2ccccc2F)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +COc1cc(C=C2CCCN3CCC(c4ccc(F)cc4)ON=C23)ccc1-n1cnc(C)c1 +CC(NC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OCc1cc2ccccc2o1)c1ccccc1 +C=C(C)CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1 +CCCC1(N2CCN(c3cc4c(cn3)C(=O)c3c([nH]c5cc(C(N)=O)ccc35)C4(C)C)CC2)CCC1 +O=C(Nc1ccn(Cc2c(F)c(F)cc(F)c2F)n1)c1ccc(COc2ccccc2Cl)cc1 +Cc1ccccc1S(=O)(=O)c1ccc(C(C)(O)C(F)(F)F)cc1 +CCc1ncnc(N2CCN(Cc3nc(C)c(C)o3)CC2)c1C#Cc1ccc(N)nc1 +O=C(O)c1csc(-n2nc(-c3ccccc3)c(F)c2-c2ccccc2)n1 +O=C(OCN1C(=O)C2=C(CCCC2)S1(=O)=O)c1c(Cl)cccc1Cl +O=C1c2ccccc2NC(c2ccccc2F)N1CCCCCN1C(=O)c2ccccc2NC1c1ccccc1F +CCOC(=O)C1=C(c2ccccc2)OC(=C(C#N)C(F)(F)F)S1 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cnc(-c5cccnc5)s4)c3)cc2C1 +Clc1c[nH]c2ncc(-c3cncc(N4CCOCC4)n3)cc12 +CCNc1nc(Nc2cn(S(=O)(=O)CCOC)nc2C)ncc1C(F)(F)F +COc1cc(C)c2nc3[nH]nc(C)c3c(C(O)c3ncco3)c2c1 +O=c1[nH]c2c(O)ccc(C(O)CNCCCOCCOCCc3ccccc3)c2s1 +CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2cccc(C)c2)n2nccc2N1 +COc1nc(-c2ccc(-c3ccccc3S(=O)(=O)NC(C)(C)C)cc2F)cnc1N +CCC(C(=O)NC(CC(=O)O)C(=O)CCCc1ccccc1)n1cc(C(C)(C)C)nc(Nc2nnn[nH]2)c1=O +Cc1cc(C)n(-c2cc(-n3[nH]cc(-c4cccnc4)c3=O)ncn2)n1 +CC(C(=O)N1CCc2c(F)cccc21)c1nc(N2CCOCC2)c(F)c(=O)n1C +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)Nc5cccc(OC(F)(F)F)c5)cn4c3)cc2)CC1 +O=C(O)CCCCCCCCC=C(c1ccccc1)c1cccnc1 +CC(O)(COc1ccc2[nH]ccc2c1)C(=O)Nc1ccc([N+](=O)[O-])c(C(F)(F)F)c1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCC4(C)CCCO4)ncc23)ccn1 +CN1CCN(Cc2ccc(Nc3ncc4cc(-c5c(Cl)cccc5Cl)c(=O)n(C)c4n3)cc2)CC1 +NC(=O)c1ccc(-c2cc3cc(O)ccc3o2)c(F)n1 +CNC(=O)c1cc2cc(C(=O)N3CCC4(CC3)CC(=O)c3c(OC)cccc3O4)ccc2[nH]1 +Cc1ccc(-n2c(C)nnc2SCC(=O)Nc2ccc(C(C)C)cc2Br)cc1 +CC1CCCC(=O)C(C)CCC=Cc2cc(O)cc(O)c2C(=O)O1 +CNC(=O)C1CCC(NC(=O)c2cnc(-n3ncc4cc(Cl)cnc43)cc2NC(C)C)CC1 +CN(Cc1ccc(CC(=O)O)cc1)c1cccc(-c2c(Cc3ccccc3)cnc3c(C(F)(F)F)cccc23)c1 +CCCCCCCCCOC(=O)C1=C(c2ccccc2)CCN(CC)C1 +CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4ccncc4C3=O)CC2)CC1 +Cc1cc(Cl)ccc1-c1ccc2[nH]c3c(c(=O)c2c1)CSCC3 +NC(=O)c1ccc(-c2cc(C(F)(F)F)nc3c(-c4cnc5ccccc5c4)cccc23)cc1N +CCc1cc2cc(NS(=O)(=O)c3ccc(C#N)cc3)ccc2n(C)c1=O +CCCCCc1cc(O)cc(OCCCCCCCC(=O)NC2CC2)c1 +CC(=O)N1CCc2c(nc(C)n2C2CC3CCC(C2)N3CCCN(C(=O)Nc2ccc(C)cc2)c2ccc(F)cc2)C1 +COc1ncc(F)cc1C1CCCN1c1ccn2ncc(C(=O)N3CC(C)(O)C3)c2n1 +COc1ccc(CNC(=O)c2ccccc2Sc2ccc3c(C=Cc4ccccn4)n[nH]c3c2)cc1 +O=C(CCC(=O)n1sc2ccccc2c1=O)c1cccs1 +CNC(=O)c1ccc(Nc2nc(OC3CCOCC3)c3c(-c4ccc5nc(C)oc5c4)c[nH]c3n2)c(OC)c1 +CC(C)c1ccc(COc2ccc(N(CCN)C(=O)c3ccc(Cl)cc3Cl)cc2)cc1 +N#Cc1ccc(CC(=O)NC2COc3ncccc32)c(Cl)c1 +Clc1cc(Nc2ncnc3ccc(-c4cccc(N5CCOCC5)c4)cc23)ccc1OCc1ccccc1 +COc1ccc(Oc2c(Cl)cnn(Cc3ccccc3C(C)C)c2=O)cc1 +CCOc1ccc(C=C(C#N)c2nc3ccccc3[nH]2)cc1OC +CCCCC(Sc1ccc(OCCCOc2cccc(C(F)(F)F)c2)cc1)C(=O)O +CCCCCCCCC(=O)N1CCN(C(CC)c2nc3ccccc3c(=O)n2C)CC1 +O=C(O)C(O)(Cc1cnc2ccccn12)P(=O)(O)O +CC(C)(C)NC(=O)N1CCn2c(c(C(N)=O)c(-c3cccc(C(F)(F)F)c3)c2C2CC2)C1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(F)c(Cl)c4)nc23)N1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +CCc1cc(=O)oc2nc(OCC3CC3)[nH]c(=O)c12 +Cn1c(=O)[nH]c2nccc(Oc3ccc(NC(=O)Nc4cc(C5CC5)nn4-c4ccccc4)cc3)c21 +CCOc1ccccc1N(C(=O)CC)C1CCN(CCc2ccccc2)CC1 +CC(C)N1CCC(Oc2ccc(-c3ccc(=O)[nH]n3)cn2)CC1 +O=c1oc2cc(OCC(O)CN3CCN(Cc4ccc(Cl)cc4)CC3)ccc2c(O)c1[N+](=O)[O-] +O=C1NC(=O)C(c2c[nH]c3ccccc23)=C1c1cc(N2CCOCC2)ccc1C(F)(F)F +O=[N+]([O-])c1ccc2c(c1)C(c1ccccc1Cl)=Nc1c(n[nH]c1-c1ccncc1)N2 +N#CC1CCCCC1n1cc(C(N)=O)c(Nc2ccnnc2)n1 +CN(C)CC1CCN(c2ccc(Cl)cc2NC(=O)c2cnn3cc(O)cnc23)CC1 +Nc1nc(CNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)cs1 +O=C(c1ccc([N+](=O)[O-])cc1)N1c2ccccc2Sc2ccccc21 +CC1CCC2C(C)C(Oc3ccc(F)cc3)OC3OC4(C)CCC1C32OO4 +CCc1c(C)nc(O)c([N+](=O)[O-])c1Oc1cc(C)cc(C)c1 +CC(NC(=O)Nc1cc2[nH]nc(C(=O)NCc3cccnn3)c2cn1)c1ccccc1 +O=C(C=Cc1cccc(Cl)c1)NCCCCCN1CCC(c2c[nH]c3ccccc23)CC1 +CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(CNC(=O)CCc3ccc(N=[N+]=[N-])c(I)c3)ccc21 +Cc1ccc2oc(=O)c(C=Nc3ccc(S(=O)(=O)Nc4cc(C)on4)cc3)c(Cl)c2c1 +O=C(O)CCc1ccc(COc2ccccc2)cc1C(=O)NCc1ccccc1 +COc1cc(Nc2nc(NCCCNc3ccnc4cc(Cl)ccc34)nc(N3CCOCC3)n2)cc(OC)c1 +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C2CCCC2)co1 +O=C(NC1CC2CCC(C1)N2CC1CCCO1)c1cccc2ccccc12 +CCC(=O)N1C(C(=O)O)Cc2c([nH]c3ccccc23)C1c1cccc(O)c1 +CC(C)Oc1sc(-c2cc[nH]n2)c2c1C(=O)CC(C)(C)C2 +Oc1cc(C=CF)c2oc(-c3ccc(O)c(F)c3)nc2c1 +COc1ccccc1N1CCN(CC(=O)Nc2cccc(C)c2)CC1 +NCc1ccc2c(c1)CN(C(=O)Nc1ccc(NC(=O)CC3CCCC3)cc1)C2 +CON(C)CC(NC(=O)C(CC(=O)N1CCOCC1)Cc1ccccc1)C(=O)NC(CC1CCCCC1)C(O)C(O)CC(C)C +NC(CC(c1ccccc1)c1ccccc1)(C(=O)O)C1CC1C(=O)O +CCCCC12CC1(C(=O)Nc1cccc(C#N)c1)C(=O)Nc1ccc(Cl)cc12 +O=C1OC(c2ccccc2Cl)CN1c1ccc2c(c1)CCNC2 +CCc1cccc(CC)c1NC(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC(C)C)cc1 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+CC(C)(N)C(=O)NC(CCc1ccccc1)C(=O)N1CCC2(CC1)CSc1ccccc12 +COc1ccc(C=CC(=O)Nc2cc(-c3c(-c4ccc(F)cc4)nc(SC)n3C)ccn2)cc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCc3ccncc3)c2)[nH]1 +O=C(Nc1nnc(C2=COCCO2)o1)c1ccc(Br)cc1 +CC(C)(C)C1COC2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N21 +CC(C)CC(NC(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)c1cccnn1 +Clc1ccc(-c2csc(NN=C3CCCCCC3)n2)c(Cl)c1 +O=C(O)CC(NC(=O)Cn1c(Cc2ccccc2)ccc(NC(=O)c2cccc3ccccc23)c1=O)C(=O)COc1ccccc1 +Cc1[nH]c2ccc(OC(F)(F)F)cc2c1Cc1cccc(OC(C)C(=O)O)c1 +O=C1c2ccccc2C(O)(c2ccc3[nH]c(Nc4ncc(Cl)cn4)nc3c2)N1c1cccc(Cl)c1F +O=S(=O)(Nc1ccc(Oc2cncc(Cl)c2)c(Cl)c1)c1ccc(Cl)cc1Cl +CC(C)(C)c1ccc(CCN2CCc3cc(S(=O)(=O)Nc4ccc(OCCOCC5CCCO5)cc4F)ccc3C2)cc1 +CC(C)C(CC(=O)OCC1(CO)CC(=Cc2ccc(O)cc2)C(=O)O1)C(C)C +O=C(NC(CCc1ccccc1)CNc1ccc(OC(F)(F)F)cc1)OC(CC1CCCCC1)C(=O)N1CCOCC1 +CC(C)(C)CC(=O)N1CCCC1C(=O)NCc1ccc(C(=N)N)cc1 +CCn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(C)c4)cc2)CC3)cn1 +NNC(=O)c1[nH]c2ccc(Cl)cc2c1Sc1ccccc1 +CN(C)C1CCN(c2ccc(NC(=O)c3ccc(-c4cccs4)cc3)cc2)C1 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+O=C(NC1CCCc2c1[nH]c1ccc(Cl)cc21)c1ccccc1 +CC(C)(C)NCC(O)COc1cccc2c1NC(=O)CC2 +Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc([N+](=O)[O-])cc1 +COC(=O)C1=C(CN2CC(C)(C)CC2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Cl +CCn1cc(C(C(=O)NS(=O)(=O)c2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)c2ccccc21 +CCCCNc1cc(NC(C)C(Cc2ccc(Cl)cc2)c2cccc(Br)c2)nc(SC)n1 +Cc1cc(C)n2nc(-c3ccc(CCCF)cc3)c(CC(=O)N(C)Cc3ccccc3)c2n1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1c(-c2ccc(Br)cc2)noc1C +Cc1cc(F)ccc1OC1CCN(CC2CCN(C(Cc3ccc(F)cc3)C(=O)O)CC2)CC1 +O=CN1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1N1CCOCC1 +Nc1nc(N)c2ncn(C3SC(CO)C(O)C3O)c2n1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cc2ccccc2n1CCCCO +Cc1cccc(C)c1Nc1ccc2c(c1)CN(CCCCCCC(=O)NO)C2=O +CC1CCC2C(Cc3cccc(F)c3)C(=O)OC3OC4(C)CCC1C32OO4 +CCNC(=O)N1CCC(NCc2cc(OC(F)(F)F)ccc2OC)C(c2ccccc2)C1 +O=c1c2cc(C#CCc3ccccc3)ccc2ncn1Cc1ccc(F)cc1 +CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2ncncc2O)cc1 +CC(C)(C)OC(=O)NCCNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +O=C(C(O)c1ccccc1)N1CCC(Nc2ccc3[nH]ncc3c2)CC1 +CCCc1nc(C(=O)NCC(O)CN2CCN(c3cccc(C)c3C)CC2)cn1-c1ccccc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(=O)COc3cccc(Cl)c3Cl)c2)[nH]1 +CCOc1cc(-c2cc(C3CCN(C4COC4)CC3)n(C(C)C)n2)cnc1N +Cn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(Cl)cc2)CC3)cn1 +O=C1CC(CN2CCC(Oc3ccccc3)CC2)CCc2ccccc21 +O=C(CN1CCOCC1)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +COc1cccc(CNC(=O)CCC2CCCN(Cc3cc4ccccc4o3)C2)c1 +CC1(N2Cc3c[nH]nc3C2)COC(c2cc(F)ccc2F)C(N)C1 +Cc1nc2ccccc2n1Cc1ccc(CNC(=O)C(O)C(O)C(=O)N2CCCC2c2csc(N)n2)s1 +O=C(C=Cc1ccc(C(F)(F)F)cc1)Nc1ccc(F)cc1 +CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4cccc(CC(=O)O)c4c3)cc12 +O=C1C=CC(=O)c2c1ccc1c2c(=O)[nH]c2ccc(Cl)cc21 +COc1cc(C)c(C(=O)N2CC3CN(CCC(NC(=O)C4CCCC4)c4ccccc4)CC3C2)c(C)c1 +Cc1cc(SC2=C(O)OC(C)(CCc3ccc(O)cc3)CC2=O)c(C(C)(C)C)cc1NS(C)(=O)=O +CC12CCC3c4ccc(C(=O)NCC(=O)O)cc4CCC3C1CC=C2c1cncc(F)c1 +O=c1ccc(-c2cc(F)cc(F)c2)nn1CC1CN(c2ncc(-c3cnn(C4CCNCC4)c3)cn2)CCO1 +O=C(O)c1cc2ccc(Cl)cc2n1Cc1ccc(Cl)c(Cl)c1 +CC(C)n1cnc2c(NCc3ccc(-n4cccc4)cc3)nc(NC3CCC(N)CC3)nc21 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+Nc1nc(Cl)nc2c1ncn2C1OC(COC2CC2)C(O)C1O +CCCc1c(OCCCCOc2cccc3c2ccn3CC(=O)O)ccc2c(C(F)(F)F)noc12 +C=CC(=O)Nc1cc(OCCOC)ccc1Nc1cc(N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)ncn1 +Cc1ncnc(N2CCN(C(=O)C3CCC3)CC2)c1C#Cc1ccc(N)nc1 +O=c1cc(N2CC3CC2CO3)nc2n1CCC(C(F)(F)F)N2CCC1CCOCC1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCCc1nc(C)c(CCc2ccccc2)[nH]c1=O +CC(C)(C)c1ccc(-c2cc(Nc3ccc4c(c3)OCCO4)cnn2)cc1 +COc1cc(CN(CC2CCCC2)C(CC(=O)O)c2ccc(C(F)(F)F)cc2)ccc1OCCN1C(=O)CCC1=O +COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(COC1=C(Cc3ccccc3)C(=O)OC1)C2=O +O=C(c1ccc(Cl)cc1)N1CCN(C(=O)N2CCOCC2)CC1 +CCN(CC)Cc1ccc(NC(=O)c2ccccc2)c(C(=O)C(=O)N(CC)CC)c1 +CN(C)C(=O)N1CCN(C(=O)C(Cc2cccc(C(=N)N)c2)NS(=O)(=O)c2ccc3ccccc3c2)CC1 +CSc1cc2c(cc1OS(N)(=O)=O)CCC1C2CCC2(C)CCCC12 +CS(=O)(=O)NC(=O)c1cc(Cl)c(-n2nc(Cl)c3cc(-c4cc(F)c(F)c(F)c4)ccc32)cc1F +N#Cc1cc2c(cc1F)nc(-c1cncc(F)c1)n2C1CC1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NS(=O)(=O)CCC(=O)O)no2)cc1C#N +Cc1cccc(CNC(COCc2ccccc2)C(=O)N2CCC3(CC2)CN(S(C)(=O)=O)c2ccccc23)c1 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+CC1CCc2cc(-c3ncccc3CO)ccc2N1C(=O)c1ccc(O)cc1O +COc1cc(OC)cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncc(F)cn5)ccc43)cc2F)c1 +CC(NC(=O)c1cccc2c1N(Cc1cccc(C#N)c1)CC2)c1ccc(C(=O)O)cc1 +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(N(C)C(=S)Nc4ccc(Cl)cc4)cc3)CC21C +c1ccc2c(c1)c1c(n2Cc2ccc(Cn3c4c(c5ccccc53)CCC4)cc2)CCC1 +CC1=C(c2ncnn2C2CCCC2)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CCOC(=O)CN1N=C(c2ccc(OC)c(OC)c2)C2CCCCC2C1=O +Cn1c(=O)c2nc(-c3ccc(-c4ccccc4)cc3)[nH]c2n(C)c1=O +COc1nc(C2CC2)c(C(=O)NC2C3CC4CC2CC(O)(C4)C3)s1 +COc1ccc(C2=NCCN2)cc1-n1cc(-c2ccc(C3=NCCN3)cc2)nn1 +CCN1C(=O)C2Cc3c([nH]c4ccccc34)C(c3ccc(Cl)c(Cl)c3)N2C1=O +CCCC(CCC)Oc1c(Br)cc(-c2ccccc2-c2nnn[nH]2)cc1NC(=O)Nc1ccccc1F +Brc1cnc(NCCc2cccs2)nc1Nc1cc(C2CC2)n[nH]1 +O=C(Nc1ccccc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +Cn1nccc1-c1cccc(CC(NC(=O)c2ccccc2)C(=O)NCC#N)c1 +CCCN(CCC)C(=O)Cc1c(-c2ccccc2)nc2ccc(C)cn12 +CCNC(=O)C1CCN(c2cccc3c2C(=O)N(C2CCCCCCC2)C3=O)CC1 +Cc1cc(NC(=O)Nc2ccc(F)cc2F)c2ccccc2n1 +COc1ccc2c(c1)C(=Cc1cc3c([nH]1)CCN(C(=O)CCN)C3)C(=O)N2 +O=C(NC(c1ccc(O)cc1)P(=O)(Oc1ccccc1)Oc1ccccc1)OCc1ccccc1 +Cc1ccccc1-c1cc(C(OCc2ccc(Br)cc2)c2cncn2C)ccc1C#N +CC(=O)NC1CCCc2c(-c3ccc(C(F)(F)F)c(F)c3)cncc21 +Cc1cccc2c(C3OCC(O)C(O)C3O)cn(Cc3ccc(C4CC4)cc3)c12 +CC1CCC(C(C)C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)C2Cc3c(cnn3-c3ccccc3)CC12 +CCc1c(CCCC(=O)O)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 +COc1cc(OCCN2CCCC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1cccc(C)c1Cl)CC2 +CC(C)C(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)CCc2ccc(Cl)cc2Cl)CC1 +CCOC(Cc1ccc(OCC=Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc1)C(=O)O +Clc1ccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)cc1 +COc1cc(C)cc(-c2c(-c3cc(NCCCCO)nc(-c4cccnc4)n3)cnn2C)c1 +Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccccc5)cc4)csc23)cn1 +c1cc(OCC2CNCCO2)c2nc(-c3nnc4ccccn34)ccc2c1 +CCCOc1ccc(-c2nc(COc3ccc(OCC(=O)O)c(C)c3)sc2-c2ccc(OC(F)(F)F)cc2)cc1 +CON(Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F)C(=O)C(C)C +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1cccc(F)c1)CC2 +CN(C)c1nc2c(c(Nc3ccc([N+](=O)[O-])cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +COc1cc(-c2cc(NC(=O)Nc3ccc(OCCN4CCCC4)cc3)cc(OC)c2OC)ccc1C(C)=NO +COc1ccc(N(C)c2nc(C)nc3ccccc23)cc1OCCCCC(=O)NO +COc1ccc(OC(CCN2CCN(c3ccccc3OC)CC2)c2ccccc2)cc1 +CC(=O)SCCC(CCCCC(=O)N(C)CCOc1ccc(CC2SC(=O)NC2=O)cc1)SC(C)=O +COc1cc2c(c(C)c1O)C=CC1C(C)(C(=O)O)CCCC21C +NC(=O)C1CC(F)(F)CN1C(=O)c1ccc(C2(O)CCC2)c(OCC2CC2)n1 +Fc1ccc(CCN2CCN(c3[nH]cnc4c5c(Cl)cccc5nc3-4)CC2)cc1F +COC(=O)N1CCC2(CC1)CC(O)(C#Cc1cccc(C)c1)CO2 +CC(C)(O)CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1CC1CCCO1 +Ic1ccc(Oc2cncc3sc(-c4nn[nH]n4)cc23)cc1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2ccc(Cl)c(F)c2)c2cc[nH]c2c1=O +Nc1noc2cccc(C(=O)Nc3cccc(CNC(=O)Nc4cccc(F)c4)c3)c12 +CN(C)C(=O)c1ccc(-c2nnn3c2CN(C(=O)CC(N)Cc2cc(F)c(F)cc2F)CC3)cc1 +CCCCCOc1ccc(C(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +O=C(O)C(Cc1ccc(O)cc1)=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1 +Cc1c(CNc2ccc3ncc(C#N)c(Nc4ccc(F)c(Cl)c4)c3c2)ncn1CCN1CCOCC1 +Cc1c(C(=O)NC(=O)OCC(C)(C)C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1nc(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)c(C)c2ccccc12 +O=C(Cc1ccc(OCCC2CC2C2CCN(c3ncc(Cl)cn3)CC2)cc1F)N1CCCCC1 +NC(Cn1ccc(=O)n(Cc2ccsc2C(=O)O)c1=O)C(=O)O +CC(=O)Nc1cc(CCOc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1 +O=C(NCC1CCOC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=C(O)c1ccc(C(=O)C(=Cc2ccc(F)c([N+](=O)[O-])c2)SCc2ccc(C(F)(F)F)cc2)cc1 +O=C1CCNc2cc[n+](c3ccccc23)CCCCC[n+]2ccc(c3ccccc32)NCC1 +Cc1c(=O)n(Cc2ccccc2)c(=O)n2cc(C(=O)N3CCC(Oc4ccccc4F)CC3)sc12 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1c[nH]c2ccccc12)OCc1ccccc1 +O=C(CC(S)C(F)(F)F)NC(Cc1c[nH]c2ccccc12)C(=O)O +Clc1ccc(-c2ccc(C3=NOC(c4ccncc4)N3c3ccc(C4CCNCC4)cc3)o2)cc1 +CCOCCn1c(COc2ccc(C=CC(=O)c3cc(-c4nn[nH]n4)ccc3O)cc2)nc2ccccc21 +CC1(C)c2cc(OCCNS(N)(=O)=O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)c1cccc([N+](=O)[O-])c1)CC2 +O=C(NC1(C(=O)NC(CCCN2CCN(CC3CCOCC3)CC2)Cc2ccccc2)CCCC1)c1cc2cc(Cl)ccc2o1 +Cc1ccc2c(c1)C(=O)N(C)c1cnc(Nc3cccc(S(=O)(=O)N4CCC(O)CC4)c3)nc1N2C 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+O=C(c1cc(Cl)ccc1-n1nccn1)N1CCOCC1Cc1cc(-c2ncon2)ccc1F +O=C(Nc1ccccc1)Nc1ccc(C#Cc2ccc3nccn3n2)cc1 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1Nc1ccc(OCCN3CCOCC3)cc1CC2 +Cn1c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(C)c1=O +Cc1ccc2nc(N(C)C)nc(NCc3ccc(NC(=O)c4ccc(Cl)cc4)cc3)c2c1 +CCC(C)(O)C(=O)OC1C(=O)OC2CC3C(C)=CC(=O)C(O)C3(C)C3C4(O)OCC23C1C(C)C4O +CN(CCCNCc1ccc2c(c1)OCCO2)c1nc(-n2ccnc2)ns1 +CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3cc(C(=O)NC4(c5ncccn5)COC4)ccc3C)c(F)c12 +CC(c1ccccc1)N1CCCC1C(=O)Nc1ccc(C=Cc2ccc(NC(=O)C3CCCN3C(C)c3ccccc3)cc2)cc1 +CCCCc1nc2cccnc2n1CCCCCOC(O)=C1C(C(C)C)=NC(C)=C(C(=O)Nc2cccnc2)C1c1ccccc1Cl +COc1cc(F)ccc1-c1nc(Nc2cc(CS(C)(=N)=O)cc(C(F)(F)F)c2)ncc1F +O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +Cc1ccc2[nH]nc(NC3CCN(Cc4ccc5c(c4)OCO5)CC3)c2c1 +C=C1C(=O)C23C(OC(=O)C=Cc4ccccc4OC)C1CCC2C12C=CCC(C)(C)C1C(O)C3(O)OC2 +CCN(CCOC)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +COc1ccc(C2CCN(CC3CCN(C(=O)C=Cc4ccc(Cl)c(Cl)c4)CC3)CC2)cc1 +CCCn1c(=O)c2nc(C3CCCC(NC(C)=O)C3)[nH]c2n(CCC)c1=O +CCN(CC)CC(O)COc1ccccc1C(=O)CCc1ccccc1 +Cc1ccc(N2CCc3ncnc(NCc4ccc(C)c(F)c4)c3C2)c(C#N)c1 +CCC1C2Cc3ccc(O)cc3C1(CC)CCN2Cc1ccoc1 +CN1CCN(CC(=O)NCCNc2ccnc3cc(Cl)ccc23)CC1 +CC=Cc1cccc2c(=O)oc3c(C)c(O)ccc3c12 +CS(=O)(=O)c1ccc(-c2[nH]c(SC#N)cc2-c2ccc(F)cc2)cc1 +O=C1c2ccccc2C(=Cc2ccc([N+](=O)[O-])cc2)c2sccc21 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3C(=O)N3CCOCC3)cc2)cs1 +COc1ccc2c(c1)C(=O)C(=Cc1cc(Br)c(O)c(OC)c1)C2=O +CCc1cnn2c(NCc3cccnc3)cc(-c3ccccc3)nc12 +CCOc1cccc(Cc2cn(COCCO)c(=O)[nH]c2=O)c1 +CSc1ccc2c(C)nc(CCCCCCC(=O)c3ccccc3)n2n1 +O=C(Nc1ccc2c(c1)C=Nc1c(Cl)ncnc1O2)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cc1ccc(N=Cc2nc(-c3ccc(C(F)(F)F)c(F)c3)oc2O)c(C(=O)O)c1 +CN1C(=O)CCc2c(NC(=O)NC3CCC(c4ccccc4F)C3)cccc21 +COCCN1CCN(c2ccc3ncnc(Sc4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4C)c3n2)CC1 +CCc1cnc(C)nc1-c1ccc(N(Cc2ccsc2)C(=O)c2ccc(O)cc2O)cc1 +CCn1cc(Br)c2cnc(NC(=O)c3ccc(C(C)(C)O)cc3)cc21 +COc1ccc(S(C)(=O)=O)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 +Nc1nccc(Oc2ccc(-n3cc(C(=O)NCc4ccc(F)cc4)ccc3=O)cc2F)c1C#CCO +O=C(CCc1ccc(Nc2nccc(Nc3cc(C4CC4)n[nH]3)n2)cc1)NCCN1CCCCC1 +O=C(Nc1cc(OC(F)(F)F)cc(-c2cccnc2)c1)N1CCc2ccc(Cl)cc21 +O=C(Cc1ccccc1)Nc1ccc2c(c1)C=CS(=O)(=O)O2 +COC(=O)CCC(=O)NC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5 +CCCn1cc(-c2ccccc2)nc1SCc1cn2c(C)cc(C)nc2n1 +O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CCN(Cc2ccccc2-c2ccc3ccccc3c2)C1 +Cc1cc(-c2cn(CCN3CCCC3)c(C3CCN(c4ncnc(N)c4OC(C)C)CC3)n2)ccc1F +COc1ccc(-n2c(C)nc(C(=O)NCC(O)CN3CCN(c4cccc(Cl)c4C)CC3)c2C)cc1 +Cc1nc2c([N+](=O)[O-])c(Cl)c(Cl)cc2n1Cc1ccc(C#N)cc1 +CNC(=O)C(NC(=O)C(CC(C)C)C(NCCCSC)C(=O)NO)C(C)(C)C +CCOC(=O)C1=C(CC)NC2=C(C(=O)CC(C)(C)C2)C1c1ccc(Cl)cc1Cl +CC(C)=CC(=O)Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1ccccc1Cl +Cc1nc(-c2ccc(CNC(=O)NC(CC(C)C)C(=O)N(C)N(C)C#N)cc2)no1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ncc(-c2cccc(C(F)(F)F)c2)cn1 +CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1C(C)C +O=C(Nc1cccc2c1OC(C(=O)O)CN2)c1ccc(OCCCCc2ccccc2)cc1 +Cc1ccc(N2OC3C(=O)N(c4ccc(C(=O)O)cc4)C(=O)C3C2c2ccccc2O)cc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1cc(-c2ccc(Cl)c(Cl)c2)no1 +COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1OCCCCCC(=O)NO +COC(=O)c1c(-c2ccccc2)c2cc(Br)ccc2c(=O)n1Cc1ccc(NS(=O)(=O)c2ccccc2)cc1 +CC(O)C(CCc1cccc(Cl)c1Cl)n1cnc(C(N)=O)c1 +O=C(O)c1cccc(NC(=O)c2nc(C3CCCCC3)[nH]c2COC23CC4CC(CC(C4)C2)C3)c1 +CCCn1cnc2c(N3CCOCC3)cc(-c3ccc(NC(=O)NCC)cc3)nc21 +Cc1c[nH]c2ncnc(N3CCC(CCN(C)C)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12 +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2nc3ccccc3s2)CC1 +NS(=O)(=O)c1ccc(Sc2c(F)c(F)cc(F)c2F)c(C(=O)NCCc2ccccn2)c1 +CCN(CC)Cc1ccc(-c2ccc(CN(CC)CC)cc2)cc1 +CCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1C +CN1CC=C(c2cc(C(F)(F)F)ccc2N2CCOc3cc(S(=O)(=O)Nc4ccncn4)ccc32)CC1 +COc1cc2c(c(OC)c1OC)-c1c(cc3c(c1OC)OCO3)CC(C)C(C)(O)C2OC(=O)c1ccccc1 +Cc1ccc(C(=O)N(CCCN)C(c2oc3cc(Cl)ccc3c(=O)c2Cc2ccccc2)C(C)C)cc1 +Cc1ccncc1CCCC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCC(=O)O +CC1(C)CC(=O)C(C(C2=C(O)CC(C)(C)CC2=O)c2ccccc2)=C(O)C1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1ccccc1Cl +CCc1ncnc(N2CCN(C(=O)NC)CC2)c1C#Cc1ccc(N)nc1 +CCCCCCCCCCCC[n+]1ccc(C(=O)NCCCCCCNC(=O)c2cc[n+](CCCCCCCCCCCC)cc2)cc1 +CC(NC(=O)OCc1ccccc1)C(=O)NC(CCc1ccccc1)CNc1ccc(N2CCCCC2)cc1 +COc1ccc(S(=O)(=O)N2CCOC23CCN(C(=O)Nc2ccccc2)CC3F)cc1OC +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(Oc2cc(Cl)ccc2Cl)C1 +CC(C)CCc1nc2ccccc2n1Cc1cc(=O)[nH]c2c(F)c(F)ccc12 +CCCCSCC(=O)N1N=C(c2cc3ccccc3oc2=O)CC1c1ccc(C(F)(F)F)cc1 +Cc1ccc(CN2CCCC(N3CCC(c4ccc(O)cc4)CC3)C2=O)cc1 +O=C(O)CC1Sc2ccccc2N(Cc2nc3c(F)c(F)cc(F)c3s2)C1=O +Clc1ccccc1-c1cc(NCOc2cccnc2)n2ncc(Br)c2n1 +O=S1(=O)Nc2c(cc(Cl)c3cccnc23)-c2ccccc21 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(NCc3ccccc3)cc(-c3ccccc3)n2)CC1 +COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CN(C)CCO1 +O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc(COc2ccc(C(F)(F)F)cc2)cc1 +N=C(N)NCCCC(NC(=O)C1CCC2CN(S(=O)(=O)Cc3ccccc3)CC(=O)N21)C(=O)c1nccs1 +CCN(CC)c1nc(C)nc2c1ncn2-c1ccc(C(C)C)cc1Br +CN(CCO)c1cc(Sc2nc3ccccc3s2)c2nonc2c1[N+](=O)[O-] +CC1CCCN1C1CCN(c2ccc(N3CCC4(CCNCC4)C3=O)c(C(F)(F)F)c2)CC1 +COc1cc(-c2cc3ncccc3c(OCC3CNC(=O)C3)n2)cc(OC)c1OC1CCOCC1 +O=C(NC1CC(=O)N(c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)C1=O)OCc1ccccc1 +COc1cc2c(cc1OC)C(CC(c1ccccc1)c1ccccc1)N(C(=O)C1CCCCC1)CC2 +CCC1(N2CCC(n3c(=O)c(C(=O)O)nc4ccccc43)CC2)CCCCCCC1 +Cn1c(C#N)ccc1-c1cc(F)c2c(c1)C(C)(C)C(=O)N2CCc1ccccc1 +COc1cc(CNC(=O)C=C(C)C=CC=C(C)C=CC2=C(C)CCCC2(C)C)ccc1O +CC(C)(C)CCN1CCN(CC2CCC(c3ccc(Cl)cc3Cl)N(c3ccc(Cl)cc3)C2)CC1 +Cc1ccc(OCC(=O)Nc2ccc(-c3nc4ncccc4o3)cc2)c(C)c1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc[nH]c1=O +O=[N+]([O-])c1ccc(CSc2ncnc3c2ncn3Cc2ccccc2)cc1 +CC1C(=O)Nc2cccc3ccc(cc23)Oc2cc(ccc2C#N)Cn2cncc2CN1Cc1ccccc1 +Cc1ccc2ccc(S(=O)(=O)NC3CCN(Cc4cccc(C(=N)N)c4)C3=O)cc2c1 +CC(C)C(O)(c1ccc(-c2ccccc2)cc1)c1c[nH]cn1 +CCOC(=O)N1CC(CC(=O)O)C(c2cccc(OCCc3nc(-c4ccccc4)oc3C)c2)C1 +CCNC(=O)c1ccc(C(C2=CN(OC)C=CC2)=C2CC3CCC(C2)N3Cc2ccoc2)cc1 +CCCCNC(=O)C(C)CC(O)C1CSCC=CCSCC(N)C(=O)NC(C)C(=O)N1 +CCNC(=O)Nc1cccc(C23CCC(N(CCCN4CCN(C)CC4)C(=O)Nc4ccc(F)c(Cl)c4)C2C3)c1 +CCc1cc2c(=O)n3c(nc2s1)-c1[nH]c2ccc(OC)cc2c1CC3 +Cc1nnc(OC2CCNCC2)cc1C(=O)NCC12CC3CC(CC(C3)C1)C2 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)C1CCC1 +CCCN(CCC)C1CCc2cc(F)c3[nH]ccc3c2C1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3ccccc3F)ccc2[nH]1 +CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2ccc(CO)cc2)n1 +Cn1ccnc1-c1ccccc1OCC(=O)NCC(O)CN1CCc2ccccc2C1 +O=C1C(C=Nc2ccc(F)cc2)=C(O)c2ccccc21 +COc1ccc(S(=O)(=O)N2c3ccccc3CCC2CCS(=O)(=O)N2CCC(NCc3ccc(F)cc3)CC2)c(OC)c1 +COC(=O)c1oc2ccccc2c1NC(=O)CSc1ccc([N+](=O)[O-])cc1 +Cc1noc(C)c1S(=O)(=O)Nc1c(N2CCC(N(C)Cc3ccc(OC(F)F)cc3)CC2)c(=O)c1=O +CC(CC1CCc2c(cccc2OCC(=O)O)C1)=NOC(c1ccccc1)c1ccccc1 +Cc1cn(CC(CC(=O)O)NC(=O)OCc2ccccc2)c(=O)nc1NCCCCNc1nc2ccccc2[nH]1 +Cc1cc(C(=O)Nc2ccc(C(=N)N3CCCCC3)cc2F)n(-c2cc3ccccc3cc2F)n1 +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(sc5c(C#N)cccc54)c3=O)CC21 +CNC1CCC(c2ccc(Cl)c(Cl)c2)c2cc(S(C)(=O)=O)ccc21 +Cc1ccc(COC(CCCCCC(=O)NO)C(=O)Nc2ccccc2)cc1 +Cc1cc(Cl)c2cccc(CN3CC(O)C(O)C3CO)c2n1 +O=C(O)CCc1ccc(OCc2cccc(-c3ccccc3)c2)cc1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(NC(=O)NC34CC5CC(CC(C5)C3)C4)cc2)CC1 +O=C(CCn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)NC3)NCCN1CCCCC1 +Cc1c(C(F)=CC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCCOc1ccc([N+](=O)[O-])cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 +Cc1cc(C)c(NC(=O)N(Cc2ccc(-c3ccnn3C)cc2)C2CCCCCC2)c(C)c1 +NC(=NCc1ccncc1)Nc1cccc(C(=O)N2CCC(C(=O)NC(CC(=O)O)c3ccc4c(c3)OCO4)CC2)c1 +COC(=O)c1cc(C=CC(=O)O)ccc1-c1ccc(O)c(C23CC4CC(CC(C4)C2)C3)c1 +CCS(=O)(Cc1cc(F)cc(Nc2ncc(F)c(-c3ccc(F)cc3OC)n2)c1)=NC#N +O=C1c2ccccc2NC(c2ccccc2F)N1c1ccc(OCCn2ccnc2)cc1 +CC(C)Nc1cc(=O)n(-c2ccccc2)nc1-c1nc[nH]n1 +COc1cccc(SCc2cnc3nc(N)nc(N)c3c2C)c1 +CC(C)(C)NC(=O)C1CCCCC1CC(O)C(Cc1ccccc1)NC(=O)C(CC(N)=O)NC(=O)OCc1ccccc1 +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3cccs3)cc2)cc1 +CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(OC)cc12 +COCCOc1ccn2c(C(=O)Nc3cccc4c3c(OC)nn4Cc3ccc(C)nc3)cnc2c1 +O=C(O)c1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12 +O=C(NO)c1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c2cccc(Cl)c2)cc1 +N#Cc1cnc2ccc(NCc3ccc(S(N)(=O)=O)cc3)cc2c1Nc1ccc(F)c(Cl)c1 +Cn1c(CN2CCN(c3ccc(C(F)(F)F)cn3)CC2)nc2ccccc21 +Cc1nc[nH]c1CSCCNC(N)=NC(C)Cc1c[nH]cn1 +CN1CCC(c2ccc(Cl)cc2)C(C[S+]([O-])CCO)C1 +CC(C)Cc1cn(-c2cccc(C(=O)O)n2)c2cc(Cl)ccc12 +CC(C)c1ccccc1Sc1ccc(-c2cc(N3CCC(CCO)CC3)ncn2)cc1C(F)(F)F +Nn1c(SCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2sc3c(c2c1=O)CCNC3 +CC(Nc1ncnc(N)c1C#Cc1ccc(F)cn1)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(CNS(C)(=O)=O)c1 +CC(=NNC(N)=S)c1ccc(NC(=O)c2ccccc2)cc1 +CC1(C(=O)O)Cc2cc(OCCCOc3ccc(OCC(F)(F)F)cc3Cl)ccc2O1 +COc1ccc(S(=O)(=O)Nc2ccc(NS(=O)(=O)c3cccc(OC)c3)c3ccccc23)cc1 +CN(C)C(=O)C(c1c(F)cccc1F)N1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)C1 +CCCCNC(=O)C(C)CC(O)C1COCC=CCSCC(NC(C)=O)C(=O)NC(C)C(=O)N1 +COc1cc2c(cc1OC)CN(CC(=O)Nc1ccc3c(c1)C(=Cc1cnc[nH]1)C(=O)N3)CC2 +O=C(O)c1cccc(-c2csc(C3CCCCN3C(=O)COc3ccccc3)n2)n1 +CCOC(=O)C=Cc1c(OC)ccc2cc(-c3cccc(OC)c3)ccc12 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+Cc1nc(NC(C)c2cccc(-c3cnc(N4CCN(CCOCCO)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CC(C)=CCN1CCC23CC(=O)CCC2(O)C1Cc1ccc(C(N)=O)c(O)c13 +N=C(N)SCCCn1cc(C2=C(Nc3ccccc3)C(=O)NC2=O)c2ccccc21 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCN(Cc5c(C)cccc5C)C4)cc23)ccn1 +CC(C)(Oc1ccc(-n2cccn2)cn1)C(=O)NC1C2CC3CC1CC(C(N)=O)(C3)C2 +CCN1CC=C(c2ccccc2)C(C(=O)OCC2CCCCC2)C1 +COc1cccc(NN=C2C(=O)NN=C2c2cccc(OC)c2)c1 +COc1cc2c(cc1OC)CN(C(=O)C(NCc1cccs1)C(C)(C)C)CC2 +CC(c1ccccc1)N1C(=O)C2(CCCC2)C2=C1N=C(c1ccccc1)NC2N +CCCc1nc(SC(F)F)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CCc2ccccc2)cc1 +CC(=CC(=O)NC(C(=O)N1CCCC1C(=O)Nc1ccccc1)C(C)(C)C)c1ccc(OP(=O)(O)O)cc1 +COc1ccc(CN(C)C)cc1Nc1nccc(-c2c(-c3cccc(NC(=O)c4c(F)cccc4F)c3)nc3sccn23)n1 +NCc1ccc(Cl)cc1CNC(=O)C1CCCN1C(=O)C1(O)c2ccccc2-c2ccncc21 +CCC1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=Nc1ccccc1C +N#Cc1cccc(CNCC2CCN(C(=O)c3ccc(Cl)c(Cl)c3)CC2)n1 +N#Cc1c(N)nc2sc(C(=O)c3cccc(Cl)c3)c(N)c2c1-c1ccccc1Br +COC(=O)c1cn(C2CC(C(=O)NCc3ccc(OC)cc3)N(Cc3ccsc3)C2)nn1 +CC(=O)N1CC2CC1CN2Cc1cc2cc(Oc3nc4cnccc4s3)ccc2o1 +COc1ccc(-c2c[n+](Cc3ccccc3Cl)c3n2CCC3)cc1 +CNc1nnc(-c2ccc3[nH]cc(-c4cccc(-n5cnc(C)c5)n4)c3c2)s1 +C=C1C(=O)C23CC1CC(OC(C)=O)C2C1(C)C(OC(C)=O)CC(O)C(C)(C)C1C(=O)C3OC(C)=O +CC(=O)N1Cc2[nH]c(-c3cc(C(=O)N4CCC(c5ccc(C#N)cc5)CC4)c(C)cc3C)nc2C(C)(C)C1 +N#CCc1ccc(NCC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +CC(C)OC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1 +CCCCCc1nc(SCc2ccc(-c3ccccc3C#N)cc2)nn1Cc1ccc(-c2ccccc2-n2cnnn2)cc1 +COC1CCC(n2c(=O)c(-c3cn[nH]c3)cc3c(C)nc(N)nc32)CC1 +CC(C)C(CN1CCC(C)(c2cccc(O)c2)C(C)C1)NC(=O)C1Cc2ccc(O)cc2C[S+]1[O-] +CC(C)(C)c1ccc(C(=O)N2CCc3c([nH]c4ccc(O)cc34)C2)cc1 +COC(=N)c1nc2ccc3ncnc(Nc4ccc(OC)c(O)c4)c3c2s1 +CN(CC(CCN1CCC(O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1cccc2ccccc12 +CC(=NOCC#N)c1ccc(Sc2cc(C3(C)COC(C)(C)O3)cs2)cc1 +CCCCOC(=O)NS(=O)(=O)c1ccc(CC(C)C)cc1-c1ccc(Cn2cncn2)cc1 +Cc1nc2ccc(Nc3ncc(NC(=O)C(C)(C)O)c(=O)n3Cc3ccc(Cl)cc3)cc2s1 +CN(C)CCN1C(=O)c2cccc3c2c(cc2[nH]c(-c4ccccc4)nc23)C1=O +O=C(O)c1cccc(Cc2cc(Cl)ccc2OCc2ccc(F)cc2)n1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2c(OC(F)(F)F)cccc21 +N#Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCCCNc1nc2c(S(=O)(=O)c3ccccc3)nnn2c2ccsc12 +C=Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 +CN1CCC2(CC1)CCN(C(=O)Cn1cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n1)C2 +CCOP(=O)(OCC)C(CC)OC(=O)COc1ccc(Cl)cc1Cl +CC(=Cc1ccc(-c2ccccc2)cc1)CN(C)Cc1ccc2c(c1)OCCC2 +c1cc(NC2CCNC2)nc(-c2cnc3ccccn23)c1 +COCCOCCOCCOC(=O)OC[n+]1ccc(NC(=NCCCCCCOc2ccc(Cl)cc2)NC#N)cc1 +CCN1CCN(c2ccc(NC(=O)c3ccccc3Cl)cc2Cl)CC1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCNC(=O)C3)cc2F)cn1 +CC(=O)NC1CCC(CCN2CCC(Oc3cccc(C(F)(F)F)c3)CC2)CC1 +CCOC(=O)c1c(Cc2ccc(OC)cc2)[nH]c2c1cc(O)c1ccccc12 +COc1cccc(-n2ncc3c(NN=Cc4ccc(O)cc4)ncnc32)c1 +O=C(OC1CC2(N3CCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2)c1ccncc1 +COC(=O)C(C)(C)NC(=O)c1ccc(C2CC2)c(Nc2ccc(Cl)cc2Cl)n1 +Cn1cnc2cc(-c3ccc(CN)cc3)nc(NC3CCOC3)c2c1=O +CCS(=O)(=O)NCC1CCC(NC(=O)CN2C(=O)CC(C)(C)Sc3ccccc32)CC1 +C#CCN(Cc1ccc2nc(C)n(C)c(=O)c2c1)c1ccc(C(=O)NCc2ccc(Cl)cc2)cc1 +CC(C)(C)OC(=O)N1CCN(C(=O)Nc2cnc3ccc(N4CCCC4c4cc(F)ccc4F)nn23)CC1 +N=C(N)c1ccc(-c2csc(N(CCC(=O)O)C3CCN(CC(=O)O)CC3)n2)cc1 +FC(F)(F)c1cncc(Cc2ccc(-c3ccccc3)nc2)c1 +O=C(Nc1ccc(Br)cc1)NC(Cc1ccccc1)C(=O)N1CCCC1 +CCOC(=O)c1ccc(-c2[nH]nc3c2C(=O)c2c(NC(N)=O)cccc2-3)s1 +CN(C)C(=N)NC1=NC(=O)C(=Cc2ccc(N3CCC(NCC(O)COc4ccccc4)CC3)cc2)S1 +CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCCCC4)cn3)nc2n(C2CCCC2)c1=O +Cn1cnc2cc(-c3ccc(OCCO)cc3)nc(N3CCC(CO)C3)c2c1=O +Cc1cc(C(=O)Nc2cccc(OC(F)(F)F)c2)nn1-c1cccc(C(F)(F)F)c1 +CN(C)C1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +COc1ccc(S(=O)(=O)N2CCCC2C(=O)Nc2cc(C)cc(C)c2)cc1OC +CC(Nc1nccc(N2C(=O)OCC2C(C)F)n1)c1cn(-c2ccc(Cl)c(F)c2)cn1 +CCc1ccc(C(=O)Nc2cc(CN3CCN(C)CC3)cc(C(F)(F)F)c2)cc1C#Cc1ccc2ccnn2c1 +COc1ccc(C(=O)N2CC3CN(c4nc5ccc(Cl)cc5s4)CC3C2)c(OC)c1 +CC(C)Sc1cc(-c2ccc(CCNCC(O)c3ccccc3)cc2)ccc1C(=O)NS(C)(=O)=O +O=C(Nc1ccc(F)cn1)c1cccnc1Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1 +O=C(NO)C1C(c2ccccc2)C1c1ccc(C(F)(F)F)nc1 +COc1ccc(S(=O)(=O)N2CCCCCC2C(=O)NO)cc1 +CN(C)Cc1ccc(N2CCC(Oc3nc(-c4ccncn4)cc(=O)n3C)CC2)cc1 +CN1Cc2c(C3=CCN(C4CCC(C(=O)O)CC4)CC3)[nH]c3nccc(c23)-c2cc(F)c(F)cc21 +O=C(C1CC(N2CCN(c3ncccn3)CC2)CN1)N1CCCC1 +O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2nc3ccc(Cl)cc3s2)C2C=CC1C21CC1 +CC1=Nc2ccc(Cl)cc2C(c2ccccc2)N1Cc1ccccc1 +CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)O)[nH]c2cc(Cl)ccc12)C(=O)NCCN1CCOCC1 +COc1ccc(C(=O)C(CC(=O)N2CCCC2C(=O)O)SC(C)=O)cc1F +CC(C)C(O)C(N)C(=O)NS(=O)(=O)C=Cc1cccc(-c2cc(N)ncn2)c1 +c1ccc2cc(NC3=NCC4(CN5CCC4CC5)O3)ncc2c1 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCCC2 +CCCCc1ccc(-c2ccc3n(c2=O)CC2CNCC3C2)cc1 +O=C(c1ccccc1)c1c(-c2ccccc2)[nH]c2ccc(Br)cc2c1=O +CCCc1c(OC(C(=O)O)c2ccccc2)c(Cl)cc2c(CC)noc12 +Cc1ncc(C#N)c(Nc2ccc3[nH]ccc3c2C)c1C=Cc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1 +O=C(Cc1c(F)cccc1F)NC1CCN(Cc2ccccc2)CC1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1nn(C(C)C)c2ncnc(N)c12 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+CC1CN(CC2CCCC2)c2ccccc2C(C)N1C(=O)Nc1cccnc1 +CSc1ccc(C(=O)Nc2ccc(C(=O)N3CCC4(C=CCCC4)Cc4ccccc43)cc2)cc1 +CC#CCn1c(N2CCCC(N)C2)nc2ccn(Cc3ccc4cc(F)ccc4n3)c2c1=O +O=C(c1ccc([N+](=O)[O-])o1)N1CCc2ccccc2C1 +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2c(F)cccc2Cl)[nH]c1=O +O=c1cc(Cc2c(F)cccc2F)nc(NC2CCCC2)[nH]1 +COc1ccc(-c2nc(C)c(C(=O)NCc3ccc(OC(C)(C)C(=O)O)cc3)s2)cc1 +O=[N+]([O-])c1ccc(C2CC(c3ccccc3)=NN2c2ccccc2)cc1 +Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cccc(F)c4F)cc3)ccc12 +COc1ccnc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 +Nc1ccc2c(c1)OCCCN2S(=O)(=O)c1ccc(-c2cnc(C3CC3)o2)cc1 +O=C(O)CCCC=CCC1C(=O)CC(O)C1C=CC(O)COc1ccccc1 +COc1ccc(Cn2ccc3c2-c2[nH]c(=O)c(S(=O)(=O)c4ccccc4)cc2CCC3)cc1 +O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC2(C(F)(F)F)CCCC2)cc1F +COc1cccc(C2C(C(=O)Nc3ccccc3)=C(C)N=c3sc(=Cc4c[nH]c5ccccc45)c(=O)n32)c1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2=O +Nc1nc2cc(-c3nn(C4CC(=O)C4)c4ncnc(N)c34)ccc2o1 +Cc1cc2ccccc2nc1N(Cc1ccc2c(c1)CCCC2)S(=O)(=O)c1ccc(C(=O)O)cc1 +CCOc1cnc(N(C)C2CCN(c3ncnc4[nH]ccc34)C2)cn1 +Cc1nnc2sc(C(=O)NC3CN(c4ccc(F)c(F)c4)C3)c(N)c2c1C +COc1ccc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)on3)cc2)cc1 +CCCc1c(OCCCOc2ccc(CC(=O)O)cc2Cl)ccc2c(C(F)(F)F)noc12 +CC1=C(C#N)C(c2ccc(F)cc2F)C(C(=O)OC(C)(C)C)=C(C)N1 +c1cc(-c2cn(CCCN3CCOCC3)c3cnccc23)ccn1 +COc1ccc(-c2nn(-c3ccccc3)cc2C(=O)NN=Cc2ccc([N+](=O)[O-])o2)cc1 +COc1ccc(C(=O)NCCOCCNc2nc(Nc3ccc(O)cc3)nc(Nc3ccc(C(=O)NCc4ccccc4)cc3)n2)cc1 +CN(CC(CCN1CCC(O)(CCCc2ccccc2)CC1)c1ccccc1)S(=O)(=O)c1cccs1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCCNC2)n1 +CC(C)CC1CNC(=O)c2cc3cnc(Nc4ccc(N5CCN(C)CC5)cn4)nc3n21 +CCS(=O)(=O)c1ccc2c(c1)nc(CC(C)C)n2CC1CCOCC1 +CCn1nc(-c2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 +COc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(=O)C(NC(=O)C(F)(F)F)c1ccccc1)CC2 +COC1=C(CCNC(C)=O)c2nc3ccccc3c3ccnc(c23)C1=O +Cc1ccc(-c2noc(CCCCCCC(=O)Nc3ccccc3N)n2)cc1 +c1ccc2nc(-c3ccc(N4CCOCC4)cc3)ccc2c1 +CON=C(COCc1ccc2ccc(C(F)(F)F)nc2c1)C(CCN1CCC(O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1 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+O=c1cc(OCc2ccc3ccccc3c2)ccn1-c1ccc(OCCN2CCCC2)cc1 +COC(=O)C1C(OC(c2ccc(F)cc2)c2ccc(F)cc2)CC2CCC1N2C +Nc1nc(-c2ccc(CCN3CCN(c4cccc5ccccc45)CC3)cc2)cs1 +CNCc1ccc(-c2cc3cccc4c3n2CCNC4=O)cc1 +N#CN=C1N(CCCCCCCOc2ccc(Cl)cc2)C(=O)C(c2ccccc2)N1c1ccncc1 +Cc1ccc(-c2ccc(Cc3nnn(C(=O)N(C)C)n3)cc2)cc1 +O=C(NC(c1cnc(Cl)c(Cl)c1)C1CCNCC1)c1ccc2cnccc2c1 +COc1c(C#N)cccc1N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 +O=C(Nc1nnc(SCc2ccccc2)s1)c1ccc(F)cc1 +COc1cc(CNC(=O)C(CC2CCCCC2)NC(=N)NC(=O)Cc2ccc(OC)c(OC)c2)ccc1F +CC(C)(C)OC(=O)NC(CCCCN)C(=O)Nc1ccc(C(=O)O)c(-c2ccc(O)cc2)c1 +CN1CCC(c2c(-c3ccc4nc(NC(=O)c5ccncc5)cn4n3)c(-c3ccc(F)cc3)nn2C)CC1 +Cc1cc(COc2ccc(C(=O)NC3(CC(=O)NO)CCN(S(C)(=O)=O)CC3)cc2)c2ccccc2n1 +CCN(CC)C(=O)C=C(C)c1ccc(OCc2c(F)cccc2F)c(OCC(=O)O)c1 +COCCOc1ccc(S(=O)(=O)C2CCN(c3cc(C(F)(F)F)nc(C#N)n3)C2)c(Cl)c1 +COc1ccc(C=CC(=O)N2CC(CCl)c3c2cc(O)c2ncccc32)cc1O +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2c(c1)C=NC2CCCO +COc1ccc(C(=O)Nc2cc(OC)ccc2NC(=O)c2ccc(N3CCCN(C)CC3)cc2)cc1 +O=C1CC(c2ccc(CC(NS(=O)(=O)c3ccccc3)c3nc4ccccc4[nH]3)cc2)S(=O)(=O)N1 +COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccccc3Cl)oc12 +CC(C)CN(CC(C)C)C(=O)c1cncc(C(=O)NC(CC(=O)O)C(=O)CSCc2ccc(F)cc2)c1 +CCc1c(C(=O)NCCc2ccc(N(C)C)cc2)oc2ccc(Cl)cc12 +Cn1c(C(=O)Nc2ccccc2COc2ccc(OCC3CCNCC3)cc2)cc2sccc21 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(CC(F)(F)F)C1 +CCCC(CCC)n1cc2c3c(nc(C)cc31)N(c1ccc(OC)cc1C)CC2 +O=C(Cc1cccc(NCC(F)(F)c2ccccn2)[n+]1[O-])NCc1cc(Cl)ccc1-n1cncn1 +CSc1nn2cc(-c3nc4c(OCC5CCCN5C(=O)C(NC(=O)c5ccccc5)c5ccccc5)cccc4o3)nc2s1 +Cn1cc[n+](CC(O)(P(=O)([O-])O)P(=O)(O)O)c1 +CC(C)COc1ccccc1-c1cc(-c2ccc(Cl)cc2)[nH]c1-c1ccncc1 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCC1CCC(N)CC1 +COc1cc(C(=O)N2CCCCC2)c(NS(=O)(=O)c2cccc3nsnc23)cc1Cl +CCN(CC)c1ccc(-c2cn3c(=O)c4ncn(C5COC(CO)O5)c4nc3[nH]2)cc1 +CC1(C)C(NC(=O)OCCCc2c[nH]cn2)C1(C)C +O=C(NO)C1Cc2ccccc2CN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +COc1cccc(-c2cc3c4c(cccc4c2)C(=O)N(CCN(C)C)C3=O)c1 +Cc1cc(NS(=O)(=O)c2ccc(NC(=O)Cc3ccc(Cl)c(C(F)(F)F)c3)cc2)no1 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+COc1ccccc1-n1nc2c(c1C(C)C)C(CC(O)CO)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O +Cc1nccn1-c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2ccc3onc(N)c3c2)c(C#N)c1 +CNc1nccc(CNc2ccccc2C(=O)Nc2ccc3c(c2)OC(F)(F)O3)n1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2cccc(C(=O)NO)c2)CC1 +O=C(Nc1ccccc1)c1cccn2c(=O)cc(N3CCOCC3)nc12 +O=C1Cc2cc(C#CCCN3CCC(Cc4ccccc4)CC3)ccc2N1 +Cc1ccc(S(=O)(=O)N(C)C2(C(=O)NC3C4CC5CC3CC(C(N)=O)(C5)C4)CCC2)cc1Cl +Cc1ccc(S(=O)(=O)N2CC(c3ccc(Br)cc3)C(C(=O)C3CO3)=N2)cc1 +COCCCn1cc(C)c2ccc(C(C)N(C(=O)C3CNCCN3)C3CC3)cc21 +Cn1c2ccnc(N3CCOCC3)c2c2ncnc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c21 +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc2c(c1)OCO2 +COc1ccc(OC(C)(C)C2OCC(CC=CCCC(=O)O)C(c3cccnc3)O2)cc1 +CC1(C)C=C(COc2ccc(-c3nc4c(C(N)=O)cccc4[nH]3)cc2)C(C)(C)N1 +O=C(NC(Cc1ccc(Cl)cc1)C(=O)N1CCC(Cn2cncn2)(C2CCCCC2)CC1)C1CCc2ccccc2N1 +Cc1ccc(C(NC(=O)Cc2ccccc2)NC(=O)Cc2ccccc2)cc1 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cncc(NC(C)C)c1 +Cc1cc(COc2ccc(S(=O)(=O)N(C)C3CCCC3C(=O)NO)cc2)c2ccccc2n1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCN(c3ccccc3C(F)(F)F)CC2)cc1 +NCC(O)CNC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +Cc1ccc(C(=O)N(CCCN)Cc2nc3cc(Cl)ccc3c(=O)n2Cc2ccccc2)cc1 +Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2CC(Cl)c1ccccc1 +CC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cnn(C)c3)nc12 +CC1NC(=O)C(c2ccc(F)cc2)=C1c1cc(Cl)c2c(c1)NC(=O)CO2 +COc1ccc(C(=O)NC(CC(=O)O)c2ccc(C)cc2)nc1-c1cc(Cl)ccc1Cl +Cc1c(-c2nnc(C(C)(C)C)s2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +NS(=O)(=O)Oc1ccc2c(=O)c(C3CCCCC3)coc2c1 +O=c1[nH]ccc2ccc(OCCCN3CCN(c4cccc5sccc45)CC3)cc12 +N#Cc1ccc(-c2n[nH]c3c2Cc2ccc(OCCCc4cccs4)cc2-3)cn1 +COc1cc(OC)cc(-c2cc3cc(OC)c(OC)cc3c(N)n2)c1 +Cc1cc(C(=O)O)c2nc(-c3ccc(-c4cccc(F)c4F)cc3)[nH]c2c1 +O=C(O)CN1C(=O)C(NC(CSCc2ccccc2)C(=O)O)CCc2ccccc21 +COc1ccc(Nc2cnc(Nc3ccc(OC)nc3)c(-c3nc(C)nc4[nH]cnc34)c2)cc1 +Cc1cnc(C)c(-c2ccc(N(Cc3ccccc3)C(=O)c3ccc(O)cc3O)cc2)n1 +O=C(CC1CCOCC1)Nc1ccc(NC(=O)N2Cc3ccc(CO)cc3C2)cc1 +CC(O)C1(CNC(=O)c2cc3cc(C#N)ccc3n2Cc2cccc(OC(F)(F)F)c2)CCCC1 +CC(N=O)c1cnc2nnn(Cc3cc4cccnc4cc3F)c2n1 +Cc1cccc(Cl)c1Nc1nc2ccc(N3CCCCC3)nc2n2cncc12 +CS(C)(=O)=Nc1cc(C2CC2)c2c(Nc3ccc(F)cc3OC(CF)CF)ncnc2c1 +Nc1nc(-c2ccccc2)cn2cc(-c3ccco3)nc12 +CCOC(=O)c1c(Cc2cccc(Br)c2)[nH]c2c1cc(O)c1ccccc12 +Cc1ncc(Cl)cc1C(=O)NC1CCC(CN2C(=O)C(C)(C)c3cccc(Cl)c32)CC1 +O=C(O)COc1cccc2c1CCC(COC(=O)N(c1ccccc1)c1ccccc1)=C2 +CCC(=Cc1cc(C=CC(=O)NO)n(C)c1)C(=O)c1ccccc1 +Oc1ccc(C2(O)CCN(CCCCc3ccccc3)CC2)cc1 +CCC(C)C(N)C(=O)NS(=O)(=O)CC(=O)NC1(C(=O)OC)C(O)CC2C(C(N)=O)=CN(C)CC21 +Cn1cnc2c(NCc3ccc(-c4ccccc4)cc3)nc(NC3CCC(N)CC3)nc21 +CC1=C(c2nc3cc(Cl)ccc3n2C)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CCC=CCNc1cccc(C(O)CNC(C)Cc2c[nH]c3c(OS(C)(=O)=O)cccc23)c1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2Oc2ccc3ccncc3c2)c2cc[nH]c2c1=O +COCCNc1cncc(-c2cn(-c3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3C)nn2)c1 +O=C(c1ccccn1)C1CCN(CC(=O)N(Cc2nc3c(c(=O)[nH]2)COCC3)CC2CC2)CC1 +Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(=O)NCCc1ccc(OC(C)(C)C(=O)O)cc1 +Cc1ccccc1N1CCN(C(=O)C(Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)CC1 +CCCCN(CCCC)c1cc(C)nc2c(-c3ccc(Cl)cc3)nn(C)c12 +COC(=O)Nc1ccc(-c2ccnc(C(Cc3ccccc3)NC(=O)C=Cc3cc(Cl)ccc3-n3cnnn3)c2)cc1 +O=S(=O)(NC1CCN(CCOc2cccc3c2CCCC3)C1)c1cccs1 +CC(=O)Nc1cccc(N(C)CCCN2CCN(c3ccccc3)CC2)c1 +COCc1cc(OC)c(-c2csc3c(N(C(C)C)C4CCOCC4)c(OC)nn23)c(OC)c1 +Nc1ncc(-c2cnn(C3CCCNC3=O)c2)c2scc(-c3ccc(Oc4ccccc4)cc3)c12 +CC(C#N)NC(=O)C(C)c1ccc(OC2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)C=Cc2cccc(I)c2)CC1 +CCN1CCN(C(N=O)c2ccc(C#CC3(CN4Cc5ccc(OC)c(F)c5C4=O)NC(=O)NC3=O)cc2F)C(C)C1 +Cn1nc(OC2c3cc(C#N)ccc3OC(C)(C)C2O)ccc1=O +COc1ccnc(N2CC3CN(C(=O)c4cc(F)ccc4-c4ncccn4)CC3C2)n1 +Cc1c(Cc2ccccc2)nnc(N2CCC(C#N)(c3ccc(C(C)(C)O)cn3)CC2)c1C +CS(=O)(=O)NC(=O)c1ccc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)cn1 +CN1OC2(N=C1N)c1cc(C#CC3CC3)ccc1CC21CCc2ccccc2CC1 +COc1ccc(CC(=O)N(C)C)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +Cc1ccc2c(c1Cl)NC(=O)C2(c1ccc(O)cc1)C1CCCCCC1 +CC1(C)OC(=O)c2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)s3)cc21 +CCN(Cc1ccccc1)C(=O)c1nc(-c2ccccc2F)c2ccccc2n1 +O=C(O)CCc1ccc(C#Cc2cc(Cl)nc(Cl)c2)cc1 +CC(C)Oc1ccc(Nc2ncc(NC(=O)N3CCOCC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F +CCCCOP(=O)(OCCCC)OC(c1ccccc1)C(F)(F)F +O=C(NC1CCCCC1)OCc1c2ccccc2cc2ccccc12 +O=C(c1ccc(F)cc1)C1CCN(C2CN(C(=O)c3cccs3)CCC2O)CC1 +COc1cccc(-c2ccc(CN3CCC4(CC3)C(=O)N(c3cccc(OC)c3)C(=O)N4Cc3ccccc3F)cc2)c1 +COc1cc(Sc2ccc3c(N)c(OC)ccc3n2)cc(OC)c1OC +COc1cc(C(=O)N2CCC2c2noc(-c3cccc(Cl)c3OC)n2)c(-n2nccn2)cc1Cl +O=C1C(=O)N(Cc2ccnc(F)c2)c2ccc(S(=O)(=O)N3CCC3COc3ccccc3)cc21 +Cc1cc(C(N)=O)ccc1-n1nc(C(C)C)c2c(-n3cnc(-c4cnn(C)c4)c3)cccc21 +Oc1cccc(Nc2ccnc3[nH]c4ccccc4c23)c1 +O=C1Nc2c(ccc(F)c2F)C1(c1ccc(O)cc1)C1CCCC1 +CSc1ccc(Cn2cnc3c(N(C)C)nc(C(F)(F)F)nc32)cc1 +CC(C)c1cc(Nc2cc(N3CCN(C)CC3)nc(NCc3cc(-c4ccc(F)cc4)no3)n2)[nH]n1 +CC(C)(C)CNC(=O)c1ccc(Br)c(S(=O)(=O)N2CCOCC2)c1 +Oc1nc2cccc(N3CCN(Cc4cccc(-c5ccc(F)cc5)n4)CC3)c2o1 +Cn1ncc2c(CN3CCCC4(CCN(c5cnc6ccccc6n5)CC4)C3=O)cccc21 +COc1ccc(CNC(=O)c2cnc3c(SSc4cccc5cc(C(=O)NCc6ccc(OC)cc6)cnc45)cccc3c2)cc1 +Cc1ccccc1C(=O)Nc1cc2c(cc1N1CCCCC1)n(C)c(=O)n2C +CN1C(=O)Cc2ccc(-c3cc(F)c(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3)cc21 +Cc1cc(-n2cccc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +CN(C(=O)CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)C1CCCCC1 +CCn1c(=O)n(CC)c2cc(-c3[nH]ncc3-c3cccc(C)c3)ccc21 +Cc1noc(C)c1-c1ccc2c(c1)C(C1CCCCC1)(N1CCN(C)CC1)C(=O)N2 +CC(C)c1cccc(NC(=O)c2cccc(N3CCc4c(cncc4C(=O)NCCCN4CCOCC4)C3)c2)c1 +Cc1cccc2nc3c(C(=O)NCCCN(C)CCCNC(=O)c4cccc5cc6c(C)cccc6nc45)cccc3cc12 +CCN(C(=O)O)S(=O)(=O)N1CCC(c2cc3c(-c4cncc(NCc5ccccc5)n4)ccnc3[nH]2)CC1 +CN(C)C(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C +Nc1ccnc(Oc2cc(C(F)(F)F)ccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)n1 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)Nc3ccccc3F)CCC12 +CC(C)N1CCCN(C(=O)c2ccc3c(CN4CCOCC4)cn(C)c3c2)CC1 +O=[N+]([O-])c1ccc(OCC(COc2ccc([N+](=O)[O-])cc2)OC2OC(CO)C(O)C(O)C2O)cc1 +O=C(O)c1cc(-c2csc(C(O)C(F)F)c2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1 +CCC(C)(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)C(N)=O +c1ccc(Nc2nc(-c3ccccc3)nc3ncccc23)cc1 +CCc1ccc(Cc2c[nH]c3cccc(OC4OC(CO)C(O)C(O)C4O)c23)cc1 +CC(=O)C(C)N1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +COc1ccc(CCCCNCCOc2cc(F)cc3c2OCCC3OC)cc1 +COc1ccc2ccc(=O)n(CC(O)C3CCC(NCc4cc5c(cn4)OCCO5)CO3)c2n1 +CNC(=O)c1cn(C)c2c1C(C)(C)Cc1cnc(Nc3cccc(CN4CCN(C)CC4)c3)nc1-2 +O=C1CCCC2=C1C(c1ccc(F)c(Cl)c1)C1=C(CCS1(=O)=O)N2 +O=C(C(NS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1)c1ccccc1)N(Cc1ccco1)Cc1cccs1 +N#Cc1cc(S(=O)(=O)Nc2nncs2)ccc1Oc1ccc(Cl)cc1-c1cn[nH]c1 +C=CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 +FC(F)c1ncn2c1Cn1ncnc1-c1cc(Br)ccc1-2 +CCC(C)C(NC(=O)C1CCCc2ccccc21)c1nc(C(=O)NC(CCCNC(=N)N)C(=O)O)co1 +CCCS(=O)(=O)NCc1ccc(CC(=O)N(C)C(CN2CCC(O)C2)c2ccccc2)cc1 +O=C(NCCCCN1CCN(c2ccccc2C(F)(F)F)CC1)Oc1ccc(-c2ccccc2)cc1 +CCCC[S+]([O-])c1sc2nc(-c3nccs3)cc(-c3ccc(CNC(=O)NCC)cc3)c2c1N +CCN(CC)c1nc(Nc2ccc(Cl)cc2)c2cn[nH]c2n1 +COc1ccc(CN(C(=O)n2cnc(S(=O)(=O)C3CC4CCC3C4)n2)C(C)C)cc1 +Cc1nnnn1-c1ccc(C(=O)NCc2cccc(C(=O)Nc3nc4c(s3)CC(N3CCOCC3)CC4)c2)cc1 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+CCCCNC(=O)C(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +CC1(C)C(C(=O)c2cn(CCN3CCCC3=O)c3ccccc23)C1(C)C +CCCOC(=O)c1ccc(-c2ccc(C3COC4(C=CC(=O)C=C4)O3)cc2)cc1 +CN1CCC(Nc2cc(Nc3cc(C4CC4)[nH]n3)nc(-c3ccccc3)n2)CC1 +Nc1ncnc2c1c(Oc1cccc(Cl)c1)nn2CC1CCNCC1 +CCCc1cccc(-c2cc(NC(=O)C3(C)CNC(=O)C3)nn2-c2ccccc2)c1 +CCOC(=O)c1c(-c2cccc(Br)c2)[nH]c2cc(OC)ccc2c1=O +Nc1ccccc1NC(=O)CCCCCNC(=O)c1cnc2ccccc2c1 +Cn1c(OC2CCCN(c3cccc(F)c3)C2)nc(-c2ccncn2)cc1=O +COc1cccc(C(CC(C)C)NC(=O)c2cc(COc3ccccc3)ccc2CCC(=O)O)c1 +Cn1cnc2cc(-c3ccc(N4CCS(=O)(=O)CC4)cc3)nc(N3CCC(CO)C3)c2c1=O +Cc1nn(Cc2ccc(NS(=O)(=O)c3ccc(Cl)c(Cl)c3)cc2)c(C)c1CC(=O)O +COC(C(=O)NC1CCC(OC(=O)C2CCCCC2)CNC1=O)C(O)C(O)C(O)C=CC(C)(C)C +Cc1nc(N2CCCCC2)c2nc(C3CCCCC3)cc-2[nH]1 +O=C(NCc1ccc(F)cc1)N1CCN2C(=O)c3ccncc3C12c1ccc(Cl)cc1 +Cc1c(O)nc(SCc2ccccc2)nc1Cc1c(Cl)cccc1Cl +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCCCCCCCCCC(=O)O)C(=O)O)cc1 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1Cc1ccc2ccccc2c1 +CN1C(=O)NC(=O)CC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c2ncccc12 +O=C1CCCCN1CCN(C1(C(=O)O)CC1c1ccccc1)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 +NC(C(=O)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1)c1ccccc1 +Cc1nc2cccc(-c3[nH]c4c(c3C)C(=O)NCC4)c2nc1NC(C)(C)C +CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O +CS(=O)(=O)c1ccc(-c2coc(=O)n2-c2ccccc2F)cc1 +CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3CCc2ccccc2)c2cccc(OC)c2)cc1 +CCOC(=O)C1=C(Nc2ccc(Cl)c(C(F)(F)F)c2)SCC1=O +CCCCCCCc1ccc(NC(=O)C2Cc3ccccc3CN2C(=O)c2cccc(Oc3ccccc3)c2)cc1 +CCC(=O)N1CC(OC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(c2ccc(F)cc2)C1 +CCc1nc2c(-c3ccc(OC)cc3C)ncnc2n1C(C1CC1)C1CC1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C5(C(F)(F)F)CC5)on4)c3)c2cc1OC +Cc1cccc(CNC(=O)Nc2nc(-c3ccncc3)cs2)c1 +CCCOc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CCCOCCn1c(=O)c(NCC(=O)N2CCN(C)CC2)nc2cnc(-c3ccc(OC)nc3)cc21 +O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)c1cccc(C(F)(F)F)c1 +CC12CCC(NC(=O)C3CC3)CC1=CCC1C2CCC2(C)C(n3ccnc3)=CCC12 +COc1cc(F)c(-c2nc(C(=O)Nc3cnccc3C3CC(N)CC(C)(C)C3)ccc2F)c(F)c1 +CN1C(=O)CC(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c3ncccc23)NC1=O +COC(=O)c1ccc(C(=O)N2CC3CN(CCC(NC(=O)C4CCCC4)c4ccccc4)CC3C2)cc1 +O=C(C=Cc1ccc(O)c(CN2CCCCC2)c1)c1ccc(C(F)(F)F)cc1 +NNC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccc(F)cc1 +COC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CC(=O)OC(C)(C)C)c1 +CNC(=O)c1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)cc1 +CCCCCC1(CCCCC)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)=C(O)O1 +COC(=O)C1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2 +CCCCN(Cc1cc(Cl)c(OC)c(Cl)c1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CCCCCCCCCCCCc1nnn(C(C(=O)Nc2c(C(C)C)cccc2C(C)C)c2ccccc2)n1 +Cc1ccccc1NC(=O)NC1CCCCC1CN1CCCC(Cc2ccc(F)cc2)C1 +CNC(=O)c1c(-c2ccc(F)cc2)nc2sc(-c3cc(C(=O)NC(C)(C)c4ccccc4)ccc3OC)cn12 +O=C1Nc2cccnc2N(C(=O)CN2CCN(CCCCCCCCCCNC(=S)Nc3cccc(N=C=S)c3)CC2)c2ccccc21 +O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2ccccc2c1 +c1ccc(CCCCN2C3CCC2c2c(n(-c4ccccc4)c4ccccc24)C3)cc1 +COc1cc(C2C(C#N)=C(N)Oc3cc(O)ccc32)cc(Br)c1OC +COc1ccc(C2CC(=O)N(c3ccncc3)C2)cc1OC1CCCC1 +COc1cccc(OC)c1CNC(=O)c1cc2cc(CC(C)NCC(O)c3ccc(O)c(CO)c3)ccc2n1Cc1ccccc1 +Cn1cc(-c2ccc3nc(NC(=O)c4ccccc4)cn3n2)c(-c2ccc(F)cc2)n1 +CCC(NC(=O)c1cc(C(=O)NCc2ccccc2C#N)n2c1COCC2)c1ccccc1 +Cc1n[nH]c2c1C(c1ccc(-c3ccc(Cl)cc3)o1)C(C#N)=C(N)O2 +CCC(C1=C(O)OC2CCCCC2C1=O)c1cccc(NS(=O)(=O)c2ccc(C#N)cc2)c1 +CC(=O)N1CCC(Nc2ncnc3c2ncn3C2OC(CO)C(O)C2O)C1 +COc1ccc(CCNC(C)COc2c(C)cc(Cl)cc2C)cc1OC +CN1CCN(CCNc2nc3cc(Cl)c(C#N)cc3nc2-c2ccccn2)CC1 +Cc1cccc(C(=O)Nc2cccc(Oc3cncnc3)n2)c1 +CCOC(=O)c1ccc(NCc2cc3c(cc2O)CCCO3)cc1 +CC(C)CCN(C(C(=O)NO)C(C)C)S(=O)(=O)c1ccc2cc(OCC(C)C)ccc2c1 +Clc1ccc(-c2cc(CNC3CCCC3)nn2-c2ccc(Cl)cc2Cl)cc1 +Fc1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCCCC4)N3)n2)nc1 +C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2)cc1 +O=C(Nc1ccccc1)Nc1nc2ccccc2n2c(=O)n(-c3ccc(Cl)cc3)nc12 +Nc1nc(N)c(C(C[N+](=O)[O-])c2ccccc2)c(N)n1 +O=C1c2ccc(F)cc2CC1CCN1CCc2ccccc2C1 +O=c1cc(-c2ccc(F)cc2)c2cc(Sc3cc(F)cc(C(O)(C(F)(F)F)C(F)(F)F)c3)ccc2o1 +Cc1cc(C)c2sc(C(=O)N(C)C)c(-c3ccc(CCNc4ncccn4)cc3)c2c1 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+Cc1cc(Nc2cccc(NC(=O)c3ccc(Nc4ccnc5ccccc45)cc3)c2)nc(N)n1 +CC(C)Nc1nc(-c2ccc(NCCN3CCOCC3)nc2)cc2ncn(C)c(=O)c12 +O=C1N(Cc2ccccc2)c2ccccc2C1(O)c1ccc2c(c1)OCO2 +COCC(Cc1cccc(C(=N)N)c1)C(C=Cc1ccccc1)NC(=O)c1ccc(-c2ccccc2)cc1 +COc1ccccc1N1CCN(CCCOc2cc(C(=O)c3cn(CCCC(=O)O)c4ccccc34)ccc2OCc2ccccc2)CC1 +O=C(Nc1cc(-c2cccnc2)cc(C(F)(F)F)c1)Nc1nccs1 +COCC(NC(=O)Nc1cc2[nH]nc(N3CCOCC3)c2cn1)c1ccccc1 +CC(C)N1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +CCCOc1c(Cl)cc(Cl)cc1CNC1CCCN(c2nc3nc(Cl)ccc3[nH]2)C1 +COc1cc(N2CCNCC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)n2cc(C(=O)NCC(F)(F)F)nc2c1C(N)=O +CN(C)CCn1cc(C(=O)N2CC(O)CC2C(=O)NC(Cc2ccccc2)C(=O)N(C)Cc2ccccc2)c2ccccc21 +O=c1[nH]c2ncc(-c3ccc4[nH]cnc4c3)nc2n1CC1CCOCC1 +CCCc1c(OC)c(NC(=O)CC)cc2c(NCc3ccc(OC)c(Cl)c3)ncnc12 +CS(=O)(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(c2ccc(F)cc2)CC1 +CCC(C(=O)Nc1ccc(-c2nsc(=O)[nH]2)cc1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O +NCC1CN(c2ccc3nc(C(F)(F)F)nn3n2)C(=O)CC1c1cc(F)ccc1F +COC(=O)CC1N=C(c2ccc(-c3ccccc3OC)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +CCN(CC)C1CCS(=O)(=O)c2sc(S(N)(=O)=O)cc21 +COc1cccc2cc(C(=O)NCCCCCCCNc3c4c(nc5ccccc35)CCCCC4)oc12 +Cc1cccc2ccc(N3CCC(C(=O)NC4CCCC(CO)C4)C(C)(C)C3)nc12 +Cc1noc(NS(=O)(=O)c2cccc(-c3ccccc3)c2)c1Cl +OC1=C2C(=Nc3ccnn3C2c2cccc(Br)c2)CCC1 +Cc1c(C(O)CN2CCN(CC(O)c3ccc4c(c3C)COC4=O)C(C)(C)C2)ccc2c1COC2=O +O=C1NC(COC(=O)c2cccc3cnccc23)CNc2cn(CCc3ccccc3)nc21 +CC(C)c1cc(-c2ccccc2)cc(C(C)C)[n+]1CC(=O)OCCOc1ccc2nc(S(N)(=O)=O)sc2c1 +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C(=O)NC2CC2)o1 +Cc1nc(N2CCC(C)CC2)c2c(C)c(C(=O)Nc3ccc(C(F)(F)F)cc3)sc2n1 +O=C(C1CC2CCC1C2)N1CC(c2nc(-c3cccc(Cl)c3)no2)C1 +CC(=O)Nc1cccc(-c2nc(C3CCCCN3C(=O)COc3ccccc3)n(C)n2)c1 +C=C1CC(OC(=O)C(C)(O)CI)C2C(=C)C(=O)OC2C2C1CC(O)C21CO1 +COc1cccc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c1C(=O)N(C)C +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCCS(N)(=O)=O)[nH]c3ccc(Cl)cc23)c1 +O=C(O)CCCC=CCC1C2CCC(C2)C1NS(=O)(=O)c1ccc2oc3cc([N+](=O)[O-])ccc3c2c1 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+COc1cc(Nc2c(C#N)cnc3cc(OCCCCN4CCOCC4)c(OC)cc23)c(Cl)cc1Cl +O=c1cc(-c2ccccc2)ncn1CCCCCN1CCN(c2ccccc2)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3cc(OC(C)C)nn3c2)c1F +CCc1c(Sc2cc(C)cc(C)c2)n(OCc2ccccc2)c(=O)[nH]c1=O +COc1ccccc1N1CCN(CC2COC3(CCN(S(=O)(=O)c4ccc(Cl)cc4)CC3)O2)CC1 +CSc1cccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Br)cc2)c1 +NC(=O)c1cccc2c(NCc3cccc(Nc4nc5ccc(C(F)(F)F)cc5[nH]4)c3)ncnc12 +O=S(=O)(c1ccc2c(c1)C1C3CCC(C3)C1C(c1ccccc1)N2)N1CCOCC1 +Cn1cc(Nc2nccc(NC3C4C=CC(C4)C3C(N)=O)n2)cn1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3ccccc3)cc2)cc1 +COc1ccc(CCN2CCN(c3ccccn3)CC2)cc1OCCc1ccccc1 +Cc1nn(Cc2ccc(C#Cc3ccc(C(F)(F)F)cc3)cc2)c(C)c1CC(=O)O +CCOC(Cc1ccc(OCC=Cc2cc(OC3CCCC3)cc(OC3CCCC3)c2)cc1)C(=O)O +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(Cn2cccn2)CN1 +COc1cc(-c2ccc3ncc4nnn(C(C)c5ccc(F)cc5)c4c3c2)ccn1 +Cc1ccc(S(=O)(=O)N2CC3(CC2C(=O)NN=Cc2ccccc2[N+](=O)[O-])SCCS3)cc1 +Cc1ccc(S(=O)(=O)Nc2nc(-c3ccc(Cl)c(Cl)c3)cs2)cc1 +N#Cc1ccc(CC(=O)Nc2nnc(CCSCCc3nnc(NC(=O)Cc4ccc(C#N)cc4)s3)s2)cc1 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+O=c1[nH]c(=O)n(CCc2cccc(C(F)(F)F)c2)nc1O +O=C(O)CCCc1ccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)cc1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccc(OC)nc3)ccc21 +CNC(=O)c1nc2ccc(CCNC(=O)Nc3cc(C(F)(F)F)ccc3OC)cc2[nH]1 +O=CC(NS(=O)(=O)c1ccccc1Oc1ccc(C2CCCC2)cc1)C(=O)O +CCN(CC)CCCC(C)Nc1cc(CCCCCCCCCCCCc2cc(NC(C)CCCN(CC)CC)c3ccccc3n2)nc2ccccc12 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CC(n5cccn5)C4)ncn3)c2c1 +CC(=NOC1CCNCC1)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +CC(C)(C)OC(=O)c1ncn2c1C1CCCN1C(=O)c1cc(-c3ccco3)ccc1-2 +Cn1cnc(CS(=O)(=O)c2ccc(Br)cc2)c1[N+](=O)[O-] +Cc1cc(SCc2nc(-c3ccc(OC(F)(F)F)cc3)ns2)ccc1OC1(C(=O)O)CCCC1 +CC(C)CC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)O +CCC(C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(C)cc1 +NC(=O)Nc1sc2c(c1C(N)=O)CCc1nn(C3CCCN(Cc4ccc(F)cc4F)C3)cc1-2 +NC(=O)c1cccc2c(NCc3cccc(Nc4nc5ccccc5s4)c3)ncnc12 +O=C(NC1C2CC3CC(C2)CC1C3)N1CCCC(c2ccccc2)C1 +CN1CCN(c2cc(Cl)c3nc(Nc4ccc(Br)cn4)[nH]c3c2)CC1 +CC1(C(=O)O)CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(N)C(C)(C)C5CCC43C)C2C1 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+Nc1[nH]cnc2c(C3NC(CSc4cccc(Cl)c4)C(O)C3O)cnc1-2 +CC(C)CC(NC(=O)C(CC(C)C)NC1=CC(=O)c2ccccc2C1=O)B(O)O +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(N(C)Cc2ccc(C(=O)O)cc2)c(C(F)(F)F)n1 +Cc1ccc2c(NCc3ccccc3)c3c(nc2c1)CCCC3 +Cn1nc(C(C)(C)NC(=O)C2C3CNCC32)c2ccccc21 +Cc1cccc(NC(=O)c2ccc(-c3ccc(F)cc3)c(C#N)c2)n1 +Oc1ccc2c(c1)C1c3cc(O)ccc3C(C2)N2CCCC12 +COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(Cl)cc2)cc1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CC3CC1CC(c1ncc[nH]1)(C3)C2 +CCN1C(=O)c2c(nc(Br)n2Cc2ccc(O)cc2)N2CC(Cc3ccccc3)N=C12 +O=C(OC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5)c1cc2ccccc2cn1 +CC(C)CN(CCCN1CCN(CCCNCc2ccncc2)CC1)CC(C)C +CCCCn1nc(Cc2ccccc2)cc1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2ccccc2)CC1 +O=C(Nc1cc2ccccc2cc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(Cl)ccn1 +COc1ccc2c(c1)c(Cc1cccc(OC(C)(C)C(=O)O)c1)c(C)n2C(=O)c1ccc(Cl)cc1 +O=C(C=C(O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccccc2F)c1=O)C(=O)NC1CCCC1O +Cc1ccccc1-c1c(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n(C)c(=O)c2ccccc12 +CCC(NC(=O)c1cc(C(=O)NC(CC)c2ccccc2)n2c1SCC2)c1ccccc1 +CC(C)(Nc1cccc(F)c1)C(=O)Nc1nc2c(C(F)(F)F)cc3[nH]ncc3c2s1 +c1ccc2c(c1)C1CC(c3ccsc3)(c3ccsc3)C2c2cccc[n+]21 +Brc1cc(CN2CCCCC2)cc(Br)c1OCCCN1CCCCC1 +O=C(NC1CCC(CCN2CCC(c3noc4cc(Cl)ccc34)CC2)CC1)C(O)C(F)(F)F +CN1CCC(S(=O)(=O)c2ccc3nc(NC(=O)NC(=O)c4cc5c(cc4Cl)CCN5C)sc3c2)CC1 +OC(CNCC1CCN(CCC(F)(F)F)CC1)COc1cccc2[nH]c3ccccc3c12 +COc1ccccc1N1CCN(CCn2c(=O)[nH]c3sccc3c2=O)CC1 +Cc1cccnc1-c1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 +CN1CCC(O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)c(COc4ccccc4Cl)n2CCO3)C1=O +O=C1NCCCCC1N(Cc1cnc2ncccc2c1)S(=O)(=O)c1ccc(Cl)cc1 +CCNc1nnc(-c2cnc(N3CCN(C4CCN(C(=O)c5ccc(Cl)nc5N)CC4)C(CC)C3)c(C3CC3)n2)o1 +CCOC(CCc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 +COC(=O)CN1Cc2c(nc(C)c(CN)c2-c2ccc(Cl)cc2Cl)C1=O +O=S(=O)(c1cccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)c1)N1CCCCC1 +O=C(Nc1cc(CO)ccn1)Nc1cccc2c1C1CCCCN1C2=O +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3ccc(F)cc3F)c(F)c2)CC1 +CC(C)CC(C=O)NC(=O)C(NC(=O)c1cc(C=O)c[nH]1)C(C)C +CC(C)n1nc(C(=O)NC2CC3CCC(C2)N3CCN2CCN(S(C)(=O)=O)CC2)c2ccccc21 +CC(=O)c1cc(NC(=O)NCCCC2CC(Cc3ccc(F)cc3)CCN2C(C)=O)cc(C(C)=O)c1 +CCCS(=O)(=O)NC(=O)c1cc(COc2ccc(-c3ccc(OC)cc3)cc2)c(C)o1 +Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)nc5)cc4=O)nc31)CN1CCCC1C2 +CC(C)(C)c1ccc(Cc2cc3c(cc2Cl)COC32OC(CO)C(O)C(O)C2O)cc1 +O=C(Nc1n[nH]c2nc(-c3cccc(O)c3)ccc12)C1CC1 +CC(c1ccc(-c2ccc(=O)n(C)n2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2)OC1=O +CCCCCCCCCCC1(C(=O)Nc2c(C)c(Cl)c(C)c3c2OC(C)(C)C3)CCCC1 +O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(COc2cnc(C3CC3)c(Cl)c2)cc1F +CN(C)CCN1C(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +N#CC1(c2cccc(C(=O)Nc3cccc(Nc4ccnc(NC(=O)C5CC5)c4)c3)c2)CC1 +Cc1cc(C)c(Oc2ccc([N+](=O)[O-])c(NC3CCN(Cc4ccc(C(N)=O)cc4)CC3)c2)c(C)c1 +COCC(=O)N1CCC(n2c(C)nc3cnc4cc(F)c(-c5ccc(Oc6nccc(C)n6)cc5Cl)cc4c32)CC1 +CN1CCN(c2cc3c(cc2Nc2ccccc2)[nH]c(=O)n3CC2CCCCC2)CC1 +CCCCCCC=C1CC(CO)(COC(=O)c2ccc(OC)cc2)OC1=O +CCCCNc1ncc(C(=O)Nc2ccc(F)cc2)c(NC2CCC(O)CC2)n1 +Cc1ccc2[nH]c3c(c2c1)CN(CCCCCCCN1CCc2[nH]c4ccc(C)cc4c2C1)CC3 +CCNC(=O)C1OC(n2cnc3c(N)nc(NC(CC)CC)nc32)C(O)C1O +CCN1CCN(Cc2ccc(Nc3ncc(F)c(-c4cc(F)c5nc(C)n(C(C)C)c5c4)n3)nc2)CC1 +COc1ccc(-c2ccc(C3CC4(C)C(CC(C)C4C(=O)C4CC4)C4CCC5=CC(=O)CCC5=C34)cc2)cn1 +COc1ccc(CNc2ccc(C(F)(F)F)c(OC3CCN(C)C3)c2)cc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2c2ccc(OC)nc2)n2c1COCC2)c1ccccc1 +O=C(c1cc(OCC(F)(F)F)c(C2CC2)cn1)N1CCCC12COC2 +N#CC1(NC(=O)C2CC(S(=O)(=O)c3ccccc3Cl)CN2C(=O)C2(c3ccc(I)cc3F)CC2)CC1 +Cc1ncccc1Oc1ccc(NC(=O)c2csc3ccccc23)cn1 +N#CC1CCCN1C(=O)C(N)CCCC(=O)N1Cc2ccccc2C1 +COc1cc2nc3c(c(N)c2cc1OC)CCC(CNC(=O)c1ccoc1)C3 +CN(Cc1ccc(-c2nccnc2NS(=O)(=O)c2ccccc2C(F)(F)F)cc1)c1cccc(F)c1 +CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)cc2OCC(F)(F)F)c1 +CC(C)(C)C(CO)NC(=O)n1c(=O)n(CCN2CCOCC2)c2ccccc21 +O=C(OC(CCCc1ccccc1)Cc1ccccc1)C1CCCCN1S(=O)(=O)Cc1ccccc1 +C=C(C)CC1CN2CCc3cc(OC)c(OC)cc3C2CC1O +O=C(NCCCCc1ccccc1)n1c(=O)oc2ccc(-c3ccc(F)cc3)cc21 +COc1ccccc1C(=O)NCC1(N2CCN(C(C)C)CC2)CCN(c2ccccc2)CC1 +CCCOCCn1c(=O)c(NCc2cnccn2)nc2cnc(-c3ccc(OC)nc3)cc21 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccco1 +COc1cc(C(=O)NC2CCN(CC3CC3)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N2CCOCC2)c1=O +CCCCNC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccc(N4CCCC4)cc3)c2C1 +CCCOc1c(OC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)CCCO +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CCN1CCS(=O)(=O)CC1 +CC(C)c1nn(C)cc1-c1nc2c(N3CCN(Cc4cccnc4)CC3)c(Br)cnc2[nH]1 +CCC(CN1CC(C)OC(C)C1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +NC1=NCC(Cc2cc(I)c(O)c(I)c2)C(N)=N1 +CN1CCCC(Oc2cccc3[nH]c(=O)c(-c4nc5ccccc5[nH]4)c(N)c23)C1 +O=C(O)CNC(=O)c1c(=O)oc(O)c2cccc(-c3ccc(F)c(F)c3)c12 +O=C(Nc1cc2c(OCCC3CCCCN3)c(-c3ccc(Cl)c(Cl)c3)c(O)nc2cc1Cl)NC1CC1 +CN1C(=O)C(=NCCc2ccc(S(N)(=O)=O)cc2)c2cc(Br)ccc21 +Cn1ccc(C2CCNCC2C(=O)N(Cc2cc(CCCC#N)cc(Cl)c2Cl)C2CC2)cc1=O +CC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3cnn(C4CCN(Cc5cccnc5)CC4)c3n2)cc1 +COc1cc(CNCc2ccccc2)ccc1NC(=O)Nc1cnc(C#N)cn1 +COc1ccc(Br)cc1C=CS(=O)(=O)Nc1ccc(F)cc1S(N)(=O)=O +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(N2CCC(c3ccc(F)cc3)CC2)C1 +C=C1C(=O)OC2C1CCC1(C)CCC(OC(=O)c3ccc(I)cc3)C(C)C21 +COc1c(OCc2ccc(F)cc2)ccnc1C[S+]([O-])c1nc2cscc2[nH]1 +CCOc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCN(C(=O)OC)CC3)s2)cc1 +CCOC1N=C(c2ccccc2Cl)c2cc(Br)ccc2NC1=O +Brc1cc(Br)c2c(c1)C(NCCCNc1nc3ncccc3[nH]1)CCN2 +COC(=O)c1sc2ccccc2c1NC(=O)CCSc1ccc(Br)cc1 +Cc1cc(COc2ccc(C3(N)CCN(C(CC(C)C)C(=O)NO)C3=O)cc2)c2ccccc2n1 +O=C(O)CN(Cc1ccc(-c2ccc(Cl)cc2Cl)cc1)S(=O)(=O)c1ccc(OC(F)F)cc1 +COc1cccc(-n2cc(COc3ccc(S(N)(=O)=O)cc3)nn2)c1 +N#Cc1ccc(-c2ccccc2Cc2nc(-c3ccc(F)cc3)c(CC(=O)O)s2)cc1 +Cc1ccc(Nc2ccc(-c3ccncc3F)nc2)c(C(=O)O)c1 +O=C(NCCC1CCN(Cc2ccccc2)CC1)c1cccnc1 +CC1CN(C(=O)C2CN(c3cnccn3)CC2c2ccc(F)cc2F)CC(C)C1(O)c1ccccc1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)N(CC(F)F)CC(F)F)c12 +CCC1CC2C(CCC3(S(=O)(=O)c4ccc(C#N)cc4)c4c(F)ccc(F)c4OCC23)NS1(=O)=O +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CC4CCOC4)ncc3Cl)C2)cc1 +Nc1ncc(-c2cn[nH]c2)c2scc(-c3ccc4c(c3)CCN4C(=O)Cc3ccccc3)c12 +O=C(OCC12CCN(CC1)CC2)c1c[nH]c2cc3c(cc12)OCCO3 +CC(C(=O)Nc1cnccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1)c1ccccc1 +COc1ccc(S(=O)(=O)N2CCCC2C(=O)Nc2ccc(F)c(C)c2)cc1 +CC(C)C(NC(=O)COc1ccccc1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)F)C(C)C +O=P1(c2ccccc2)OC(COCc2ccccc2)C(OCc2ccccc2)C(OCc2ccccc2)C1O +CC(=O)Nc1ccc(-c2ccc3c(c2)CCC(C)N3C(=O)c2ccc(O)cc2O)c(C)n1 +Cc1ccc(S(=O)(=O)NC(=O)NCCc2ccc(-c3c(C(=O)N(C)C)sc4c(F)cc(F)cc34)cc2)cc1 +COc1ccc(C(=O)c2ccc(C(=O)c3ccc(N(CC4CC4)c4ccc(Cl)cc4)cn3)cc2C(=O)O)cc1 +CCS(=O)(=O)NCCOc1nc(N2CCOCC2)nc(NS(=O)(=O)c2ccc(C(C)C)cn2)c1Oc1ccccc1OC +Cc1nn(CCOCC(F)(F)F)c2c(Nc3ccncn3)nc(N3CCCNCC3)nc12 +O=C(Nc1ccc(F)cc1)C1(C(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)[nH]c34)c(F)c2)CC1 +NC1=NC(c2cccc(Oc3ccc(Cl)cc3)c2)N(c2cccc(Cl)c2)C(N)=N1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ncc(C)cc1F)CC2 +COCc1ccc2n1CC(N1CCN(C)CC1)c1cc(Cl)ccc1S2 +CNC(=O)N1CCC(Nc2ncc(C(=O)NO)cn2)(c2ccccc2)CC1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC3CCCC3)n1)C(C)(C)CN2 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+NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccnnc3)c2)c1 +CCCC(=C(c1ccc(O)cc1)c1ccc(OCCN)cc1)c1ccccc1 +CNC(=O)OCc1ccc(Oc2c3ccccc3nc3ccccc23)cc1 +CCNC(=O)N1CCCN(c2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2NC(=O)c2cccs2)CC1 +COc1cc(C(=O)c2cc3cc(N)cc(OC)c3s2)cc(OC)c1OC +Cc1nc(CN2C(=O)c3c(nc(N4CCCC(N)C4)n3Cc3cc(F)ccc3C#N)N3CCCN=C23)nc2ccccc12 +O=C1CCC2(OCCCc3ccccc3)C3Cc4ccc(O)c5c4C2(CCN3CC2CCC2)C1O5 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cccc(-c2ccccc2O)c1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)c2ccccc2)c1 +CCCCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(C)CC2)cc1 +CCOc1cc(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)C23C)c2ccccc2c1 +CC(C)Oc1ccc(Sc2nc(N)nc3c2ncn3CCOCP(=O)(OCC(F)(F)F)OCC(F)(F)F)cc1 +CN1C(=O)CC(c2ccccc2F)C1C(O)c1ccc(-c2ccc(F)cc2)s1 +COc1ccc2cc(Br)ccc2c1CN1C(=O)C(NC(=O)C(N)C(C)O)C2(CCOCC2)Oc2ccccc21 +NC(=O)C1(c2ccncc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +COCCc1cc(C(F)(F)F)nc2nc(N)c(C(N)=O)cc12 +CC(C)=CCc1cccc2c(C3=C(O)C(O)=CC(=O)C3=O)c[nH]c12 +Nc1nnc(-c2ccccc2Nc2cccc(C(F)(F)F)c2)o1 +CNCC(Nc1ncnc2c(C(N)=O)cc(OC)cc12)c1cccc(F)c1 +O=C(Oc1ccc(F)cc1)N1CCC(N(C(=O)c2ccc(-c3cnco3)cc2)C2CC2)CC1 +CC(C)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cn3)c2)c2cnccc21 +COc1cc(C(=O)N2CCOCC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)n2ccnc2c1C(N)=O +NC(CCCN1CCN(c2ncc(F)cn2)CC1)C1CCCCC1 +CCCC(=O)N1CCC(NC(=O)C(N)Cc2c(C)cc(O)cc2C)c2cc(Cc3ccccc3)ccc21 +Cc1ccc(N(C)C)c(C(=O)N2C3CCC2C(COc2ccccn2)C3)n1 +CC1CCCN(C(C(=O)Nc2ccc3c(c2)OCCO3)c2ccccc2)C1 +CC(C)CC(NC1CCC(n2cc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)CC1)C(=O)N(C)C +CC(C)Oc1cccc(NC(=O)c2cncc(N3CC4CNCC4C3)c2)c1 +COCCC(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +Fc1ccc(-c2noc(C3CCN(c4cnc5ccc(Cl)cc5c4)CC3)n2)c(Cl)c1 +CC(C)NC(=O)c1c[nH]c2ncc(Nc3ccc(C=C(C#N)C(=O)N4CCOCC4)cc3)nc12 +CCC(=O)N1CCC(NC(=O)NC2CC2c2ccccc2)CC1 +O=C(NCc1ccc(Cl)cc1Cl)N1CC2(CCN2S(=O)(=O)c2ccc(F)cc2)C1 +COc1nccc2c1ccc1nc3cccc(C(=O)NCCN(C)C)c3nc12 +COCCCCn1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)c2cccnc21 +CN(C)S(=O)(=O)n1c(N)nc2ccc(-c3[nH]c(-c4c(F)cccc4F)nc3-c3ccccc3)cc21 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+O=C(C#Cc1ccccc1)N1Cc2c(nc3ccccc3c2O)C1c1ccc2c(c1)OCO2 +O=C(O)CNC(=O)CNC(=O)COc1ccc2nc3n(c(=O)c2c1)CCC3 +NC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(Br)n3)CC3CC32)c2ncccc12 +CCc1nn(Cc2ccc(-c3nc4nc(OC)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O +CC12CC(N)C(C)(O1)C1C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C12 +COc1cc2ncnc(Nc3ccc4c(c3)CCN4C(=O)Cc3c(C)[nH]c4cc(F)ccc34)c2cc1OC +CCOC(C)Oc1cc2ncnc(Nc3ccc(C)c([N+](=O)[O-])c3)c2c2c1OCCO2 +Cc1cc(N2C(=O)c3c(c(CO)nn3C3CC3)C2c2ccc(Cl)cc2)cn(C)c1=O +Cc1ccc2c(c1)c(C#N)cn2-c1ccc(C(=O)O)c(O)c1 +CCN(CC)c1ccc(CN(C2CCCC2)S(=O)(=O)c2ccc(C)cc2)cc1 +Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)cn4c3)c2)n(C)n1 +COc1ccc(-c2cnc(N3Cc4c(nc5ccccc5c4O)C3c3ccc4c(c3)OCO4)nc2)cc1OC +Cc1cc(-n2[nH]c3c(cnc4ccccc43)c2=O)c(Br)s1 +O=c1[nH]c2cccc(OCC3CCN(CCC4CCc5[nH]c6ccc(F)cc6c5C4)CC3)c2o1 +Nc1ccc(-c2cc3c(cc2F)c(=O)c2c(=O)[nH]sc2n3C2CC2)cc1 +COCCN(CCOC)c1nn2c(-c3ccc(OC(C)C)cc3)nnc2c2ccccc12 +CC1CCCN1CCc1cc2cc(CNc3ccc([N+](=O)[O-])cn3)ccc2o1 +O=C(O)CCN1CCCC1COc1ccc(Oc2ccc(Cl)cc2)cc1 +CC(Nc1ncnc2[nH]c(-c3ccc(C#N)cc3)cc12)c1ccccc1 +CCCCc1nn(Cc2ccccc2C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(O)CN(C(=S)CCc1nc2c(F)c(F)cc(F)c2s1)c1ccccc1 +Cn1nccc1-c1cc(Cl)ccc1Oc1ccc(S(=O)(=O)Nc2ncccn2)cc1Cl +CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)N1CC(O)C1 +CCOC(=O)c1c(C)nc2sc(C(=O)c3ccc(OC)cc3)c(N)c2c1-c1ccc(OC)cc1 +CN(C)c1ccc(-c2nnc3c(C(=O)c4ccccc4)nc4ccccc4n23)cc1 +COc1nc(C(C)(C)NC(=O)c2nnc(C)o2)nc(C(=O)NCc2ccc(F)cc2)c1OS(C)(=O)=O +CC1=NN(c2cccc(S(N)(=O)=O)c2)C(=O)C1 +COc1ncc(-c2ccc3nccc(-c4ccnnc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +CCC(CS(=O)(=O)C(C)(C)C)N1C(=O)C(C)(CC(=O)O)OC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cc1coc2c1C(=O)C(=O)c1c-2ccc2c1CCCC2(C)C +COC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4cccc(C)c4)c(F)c3)ccn2)c1 +NC(=O)c1cnc2[nH]ccc2c1NC1CCN(c2ccc(C(F)(F)F)cn2)CC1 +CC(=O)N1CCCC1C(=O)N(C1CCCCC1)C1(C(=O)NC=Cc2c[nH]c3ccccc23)CCCCC1 +COc1cc2ncc(C(N)=O)c(Nc3cc(C)ccc3F)c2cc1OC +Cc1ccc2c(C)cc(C)c(-n3c(SCC(=O)Nc4ccc(S(N)(=O)=O)cc4Cl)nnc3C(F)(F)F)c2n1 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+O=C(NC1CCOCC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +Cn1cc(-c2cnc3[nH]cc(-c4cnn(Cc5ccc(F)c(F)c5)c4)c3c2)cn1 +COC(=O)Cc1ccc(NC(=O)c2cccc(-c3cc(C(=O)Nc4ccncc4F)ccc3CN)c2)cc1 +Cc1ccc(OCCOc2c(Cl)cc(Cl)cc2Cl)c([N+](=O)[O-])n1 +CC(C)(C)n1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c(-c2ccc(F)cc2F)n1 +CCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C)cc4)cc3)[nH]c2n(CC)c1=O +CC#Cc1csc(-c2ccc3c(c2)C2(N=C(N)N(C(C)C)C2=O)C2(CCC(OC)CC2)C3)c1 +COc1cc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)ccc1OC(F)F +O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1C(F)(F)F +Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OCCO)cc2)o1 +Cc1cc(C(=O)Nc2cc(C(F)(F)F)n(C)n2)ccc1-c1nc(C2CCC3CCC(=O)N3C2)n2ccnc(N)c12 +Oc1ccc2c(c1)nc(N1CCNCC1)n2Cc1ccccc1 +COc1cc(CCC(N)(C(=O)O)C2CC2C(=O)O)cc(OC)c1 +O=C1c2cccc3c2c(nn3Cc2ccccc2)CN1C1CN2CCC1CC2 +O=C1Nc2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc2C1=O +O=C(Nc1cc(C(=O)N2CC(O)C(O)C2)nn1-c1ccccc1)c1cc(-c2ccccn2)c(F)cc1Cl +CCC1OC2(CCC3=Cc4c(cnn4-c4ccc(F)cc4)CC32C)OC1CC 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+CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CCN5CCCC5C4)cn3)nc2n1C1CCCC1 +CCCCOc1cccc(C2NC(=S)NC3=C2C(=O)c2ccccc23)c1 +COc1cc(CN(CC(C)C)C(=O)C2CCN(Cc3ccccc3)C2)cc(Cl)c1OC +COc1ccc(Oc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c(Cl)c1 +COc1ccc(C2CN(CCCc3ccc(OC)c(OC)c3)CC2CNC(=O)c2cccc(Cl)c2)cc1 +CCS(=O)(=O)N1CCC(Oc2ccc3c(c2)CCC2(CCN(C4CCC4)CC2)O3)CC1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3cccc(F)c3)CC2)nc2ccsc12 +CCCC(=O)OCCNc1cc(Sc2nc3ccccc3[nH]2)c2nonc2c1[N+](=O)[O-] +Cn1c(-c2ccco2)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O +Nc1nc(N)c2cc(CNc3ccc4ccccc4c3)cnc2n1 +CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)c2cccn2c1)C(=O)C1CC1 +CS(=O)(=O)N1CCC(C(O)c2cncnc2Nc2ccc(C#N)cc2)CC1 +CN(CCC(=O)O)C(=O)c1ccc2c(c1)CCC1C2CCC2(C)C(c3cncc(F)c3)=CCC12 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)[n+]1ccccn1 +COc1ccc2[nH]c3c(c2c1)CCN(C(=O)CCc1ccccc1)C3c1ccc(C)cc1 +Cn1c(C(=O)NC2CCCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(C)C(Oc1cc(C=C2SC(=S)N(CC(=O)O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 +CCC1CN(c2ccc(C(F)(F)F)cc2)C(=O)c2c(-c3ccnc(C)c3)cnn21 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+CC(C)(O)c1ccccc1CSC(CCC1(CC(=O)O)CC1)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1 +CCOc1ccc(CC2CN3C(=NCC3C)N2CCC2CC3CCC2C3)cc1 +COC(=O)c1ccc2c(c1)NC(=C1C(=O)Nc3c1cccc3C(F)(F)F)C2=NO +COc1ccc(N2CCN(CCCCNC(=O)C(C)(C)C)CC2)cc1 +COC(=O)c1oc2c(O)c(OC)ccc2c1C(=O)c1cc(OC)c(OC)c(OC)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CC4CCOC4)ncc3Br)C2)cc1 +CCC(CC)N(Cc1ccccc1C(F)(F)F)C1CCNCC1 +CCCCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1 +CC(C)(C)c1ccc(Sc2ccccc2N2CCNCC2)cc1 +Cc1c(Nc2nc(Cc3c(Cl)cccc3Cl)c3nc[nH]c3c2C(N)=O)ccc(N2CCNCC2)c1C +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3CC3CCCO3)ccc2[nH]1 +Cc1cncc(-c2cc3c(cn2)cnn3-c2ccc(C)c(N3CCCC(N)C3)n2)n1 +CCC(CC)N1CCN(C(=O)c2nc3c(C(N)=O)cc(F)cc3[nH]2)CC1=O +NC(=O)c1ccc2c(c1)CCOC2CCN1CCN(c2c[nH]c3cc(F)ccc23)CC1 +O=S(=O)(NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2)C1CC1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(Cl)c(-c3ccccc3OC(F)F)c(Cl)c2)cc1 +CC1CN(Cc2ccc(-c3ccccc3)cc2)C(=O)O1 +Cc1ccn2c(=O)c(CCN3CCc4oc5ccccc5c4C3)c(C)nc2c1 +COc1cc(Nc2nc(NC(C)c3ncc(F)cn3)nc(N3CCOCC3)c2F)n[nH]1 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+O=C1CC(c2ccccc2)(c2ccccc2)C(=O)N1CCCCN1CCN(c2nsc3ccccc23)CC1 +CCCCNc1ncc(C(=O)Nc2ccc(C(F)(F)F)cc2)c(NC2CCC(O)CC2)n1 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(CC(C)(C)O)ccc3Cl)nnc12 +Cc1c(NCC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)n[nH]c1-c1ccccc1 +CC1(COc2cc3c(cc2F)Oc2ccc(-c4cccnc4)cc2C32COC(N)=N2)COC1 +O=c1ccc(-c2ccc3c(c2)ncn3-c2ccccc2)cn1CCCN1CCCCC1 +COc1ccc(-c2c(F)c(F)cc3cc4n(c23)CCNC4=O)cc1 +OCc1cc(C(O)CNCCc2ccc(Nc3ccc4ccccc4c3)cc2)ccc1O +COC(=O)C(C)(C)Nc1nc2c(-c3cc4c([nH]3)CCNC4=O)cccc2nc1C +CNS(=O)(=O)c1ccc(NC2C3CC4CC(C3)CC2C4)c(NCc2ccncc2)c1 +CC1CN(C(=O)c2ccc(-c3cc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)s2)CC(C)N1 +OC(CCN1CCN(c2cccc3ccccc23)CC1)c1csc2ccccc12 +Cc1cc(-c2nc(-c3ccc(OC(F)F)c(C)c3)n3c2CCOC(C)C3)cc(CF)n1 +COc1cc(N)c(Cl)cc1C(O)CCC1CCN(CC2CCCCC2)CC1 +Cc1ccc(-n2nccn2)c(C(=O)N2C(C)COCC2Cc2cccc(-n3nccn3)c2)c1 +CN1CCN(Cc2cccc(NC(=O)Nc3cccc4c3C3CCCCN3C4=O)n2)CC1 +CC(C)(N)C(=O)NC(COCc1cc(Cl)cc(Cl)c1)c1nnnn1CCOC(=O)NCCCCO +CC(C)(C)OC(=O)N1CCc2c(sc(NC(=O)c3ccc(OCc4ccccc4)cc3)c2C(N)=O)C1 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+COC1CCN(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C(C)C1 +COc1ccc(N(C)c2cnc(SCc3c(F)cccc3F)n2-c2ccc(F)cc2F)cc1OC +NC(=O)c1cnc2ccc(S(=O)(=O)c3ccccc3)cc2c1NC1CCCCC1 +CN(O)C(=O)CC(CCCc1ccccc1)CP(=O)(O)O +c1ccc2nc(N3CC(Oc4nccnc4N4CCC5(CC4)COC5)C3)ccc2c1 +COc1ccnc(Oc2ccc(-c3c(C)n[nH]c(=O)c3C)c(C)c2)c1C(F)(F)F +CC(=O)c1cccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +CCCCOc1ccc(C(=O)NC(C)C(=O)NC2CCc3ccccc3C2)cc1 +COC(=O)C(C)Nc1c(C(=O)NCc2ccc(F)cc2F)c(=O)n(O)c2ncccc12 +CN1CCN(c2ccc(-c3cc4ncn(C)c(=O)c4c(N4CCC(N)C4)n3)cc2)CC1 +Cc1nc(NC(C)c2ccc(C)c(-c3cnc(N)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5ccccc5)CC4)cc3)[nH]c2c1=O +O=C(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc(N=Nc2ccccc2)cc1 +Nc1nc(-c2ccccc2Cl)c2c(n1)N(c1c(Cl)cccc1Cl)C(=O)NC2 +COc1cc(C2c3cc4c(cc3C(CCN(C)CCN(C)C)C3COC(=O)C23)OCO4)cc(OC)c1O +CC(C)N(Cc1ccccn1)C(=O)C(C)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O +O=C(NCCc1ccc(OCCN2CCCC2)c(Br)c1)c1cccc(C(F)(F)F)c1 +CNc1nccc(-c2cc(C(N)=O)c(-c3cc(Cl)ccc3C)[nH]2)n1 +O=S(=O)(Nc1nccs1)c1ccc2c(-c3ccc(C(F)(F)F)cc3Cl)ncnc2c1 +CNCC(O)C(c1cccc(F)c1)n1ccc2cccc(Br)c21 +CC(NC(=O)CC#N)c1ccc(CN2Cc3ccc(OCC4CC4(F)F)cc3C(F)C2)cc1 +CCC(O)(CC)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)C(C)(C)N)CC1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CN3CCNCC3)c2)cc1 +Cn1c(C(=O)N2CCCNCC2)cc2[nH]c(=O)c3ccccc3c21 +CCOc1cc(-c2nncn2C)ccc1Nc1ncc2cc(C)nc(NCC(C)(C)C)c2n1 +COc1cccc2oc(=O)nc(NCC(C)(C)c3ccccc3)c12 +COc1c(C)c(C)c([N+](=O)[O-])c(N)c1CC=C(C)CCC(=O)O +COc1ccc(CC(C(=NOCCCCC(=O)O)C2CCCCC2)n2ccnc2)cc1 +Cn1c(-c2ccccc2C(F)(F)F)nnc1-c1cccc(F)c1F +Cc1cccc(CNC(=O)NC(CC(C)C)C(=O)NO)c1 +Cc1cccc(-c2nnc3n2CCN(C(=O)c2ccc(F)cc2)C3C)n1 +CC(CC(C)(C)C)NC(=O)C1CC2CC2N1C(=O)Cn1nc(C(N)=O)c2ccccc21 +Cc1cc(COc2ccc(S(=O)(=O)N3CCN(C(=O)C4CC4)C(C(=O)NO)C3)cc2)c2c(n1)CCCC2 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(C(C)CNCc3ccccc3C)c2=O)c1 +CCOc1cc(C)nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(C(=O)NC)cc4)c3Cl)cccc12 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+CC(=O)N(C1=C(N2CCCC2)C(=O)c2ccccc2C1=O)c1ccc(F)cc1 +CC(C)(c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1)c1cccs1 +O=C1Nc2ccc(C(=O)c3ccccc3)cc2C1=Cc1cc(Br)c(O)c(Br)c1 +CCCCCCCN(CCCCCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)[nH]1)C(=O)Nc1ccc(F)cc1F +Cc1cc(CC(=O)Nc2cc(C(=O)c3cn(C(C)C)c4ccncc34)ccn2)[nH]n1 +CCN(C(=O)c1ccccc1CC(O)CCc1ccccc1C(=O)N(CCO)C1(CC)CCCC1)C(C)(C)c1ccccc1 +C[N+]1(C)CCC(OC(=O)C2(c3ccccc3)CCCCCC2)CC1 +C[n+]1c2ccccc2c(Nc2cccnc2)c2[nH]c3ccccc3c21 +CC(=O)CCCCCC(NS(=O)(=O)c1ccc([N+](=O)[O-])c(F)c1)c1ncc(-c2ccccc2)[nH]1 +CCc1[nH]c2nc(Sc3cncnc3)nc(N3CCC(N)C3)c2c1Cl +CCCN(Cc1sc(N(C)c2c(C)cc(C)cc2Cl)nc1C(F)(F)F)CC1CC1 +CN1C2CCC1CC(Oc1ccc3c(c1)C(=O)c1cc(OC4CC5CCC(C4)N5C)ccc1-3)C2 +Cc1cnc(Nc2cnn(C)c2)nc1NC1CN(C(=O)CC#N)CC12CCCC2 +CCOC(=O)c1cc2c(N)c3c(nc2nc1C)CCCCC3 +Cc1cc2ccccc2c(Cn2c(=O)c3c(nc(N4CCCC(N)C4)n3Cc3ccccc3Br)n(C)c2=O)n1 +c1ccc(-c2n[nH]c3cnc(-c4ccoc4)cc23)cc1 +C=C(C=CC=CC(=O)O)c1cc(C(C)(C)C)cc2c1CCC2(C)C +CCc1cccc2c1NC(=O)C2(c1ccc(O)cc1)c1ccc(O)cc1 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+CC1CCC2C(C)C(c3cccn3Cc3ccco3)OC3OC4(C)CCC1C32OO4 +c1ccc(CCOCCOc2ccc(C3CCNCC3OCc3ccc4ccccc4c3)cc2)cc1 +O=C1CC(c2ccccc2)CC(=O)N1CCCCN1CCN(c2ccccc2Cl)CC1 +CC1NC(=O)C(C(C)C)NC(=O)CC(C=CCCS)OC(=O)CC(O)C(C(C)C)NC1=O +CCC(=O)NC(C)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(O)C2)cc1 +COC(=O)C1=C(c2ccc3ccccc3c2)CC2CCC1C2 +CC(=O)NC(C)c1ccc(OC2CCN(c3cc(C(F)(F)F)ccn3)C2)cc1 +Cc1cccc2cc(Cn3nc(I)c4c(N)ncnc43)n(-c3ccccc3OCCN3CCOCC3)c(=O)c12 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccnc4ccccc34)cc12 +COc1ccc(-c2ccc3nnc(C(C)c4ccc5ncccc5c4)n3n2)cc1F +O=C(Nc1ccc(S(=O)(=O)N2CCCCC2c2cccnc2)cc1)c1c(F)cccc1F +Cn1cc(-c2cnc3[nH]cc(-c4cnn(Cc5cccc(C(F)(F)F)c5)c4)c3c2)cn1 +OC(c1ccccc1)C1CCN(CCCCc2ccccc2)CC1 +O=C(CCl)NNC(=O)CSc1nnc(Cc2csc(NC(=O)c3ccccc3)n2)n1NC(=O)c1ccc(Cl)cc1 +CC(O)C1CCN(c2cc(-c3n[nH]c4ccc(-c5cnn(C)c5)cc34)ncn2)C1 +CC1(C)CC=C(c2cc(CN3CCN(CCO)CC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +Cc1cccc(Cc2nc(N)nc(N3CCN(C)CC3)n2)c1 +COc1ccc2nccc(CCC3CCC(NCc4ccc5c(n4)NC(=O)CS5)CO3)c2n1 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+O=C(CCSc1nc2c(c(=O)[nH]1)CCCC2)NC1CCC(c2nnc(-c3ccccc3)o2)CC1 +COc1cccc(-c2n[nH]c(Cc3cccc([N+](=O)[O-])c3)n2)c1 +Cc1cccc(-c2csc(N3CC4CC4(C(=O)O)C3)n2)c1OCc1ccc2c(c1C)CCN(C1CCOCC1)C2 +O=C(NCC(c1cccnc1)N1CCN(c2ccccc2F)CC1)OCc1ccccc1 +COc1c(C=Cc2ccc(NS(C)(=O)=O)cc2)cc(-c2cc(F)c[nH]c2=O)cc1C1(Cl)CC1 +CC(Nc1ncnc2oc(-c3ccc(NCCN4CCCCC4)cc3)cc12)c1ccccc1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1C1CCCC1 +O=C(NC1c2ccccc2CC1O)C(CC(O)C(OCc1ccccc1)C(=O)NC1c2ccccc2CC1O)OCc1ccccc1 +O=C(NCc1ccc(Cl)cc1)c1cn2c(CCN(CCO)CCO)cc3cc(CN4CCOCC4)cc(c1=O)c32 +Cc1cccc(S(=O)(=O)c2n[nH]c3ccc(N4CCN(C)CC4)cc23)c1 +OCc1cc(C(O)CNCCc2ccc(NCC(O)c3ccc(O)c(CO)c3)cc2)ccc1O +CN(C(=O)Nc1ccn(-c2ccccc2F)n1)C1CCC2(CC1)OC(=O)c1ccccc12 +COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OCCCN(C)C +COc1ccc(CNc2ccc3c4c2OC2C(O)C=CC5C(C3)N(C)CCC452)cc1 +N#CCOc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F +CC1(c2cc(NC(=O)c3ccc(C(F)(F)F)cn3)ccc2F)CS(=O)(=O)C2(CCCC2)C(=N)N1 +OC1CNCc2nc(-c3ccc(N4CCCC4)cc3)sc21 +NC(CCSCC1OC(n2cnc3c(NCCCc4ccccc4)ncnc32)C(O)C1O)C(=O)O +CCc1cc2c(=O)n(CC3(O)CCOCC3)c(=O)n(Cc3ccc(-c4ccccc4-c4nc(=O)o[nH]4)cc3)c2s1 +CCOc1cc(=O)n(C)cc1-c1cc(NCc2cnco2)ccc1Oc1ccc(F)cc1F +O=S(=O)(c1ccc(-c2cnc(C3CC3)o2)cc1Cl)N1CCc2ccccc21 +COCc1cc(OC)c(-c2c(C)sc3c(N(CC4CCOCC4)CC4CC4)c(C)nn23)c(OC)c1 +Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCNC1 +CCn1nnnc1C1OC(n2cnc3c(N)nc(NC(CO)Cc4ccccc4)nc32)C(O)C1O +CCCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1ccc([N+](=O)[O-])cc1 +CC1CN2c3c(cc4c(-c5ccncn5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2CC(=O)N2CCCCC2)cc1 +CC(NC(=O)Nc1cccc2ccc(O)cc12)c1ccc(C(F)(F)F)cc1 +CCCC(O)C(CNCC(C)C)NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 +COc1cccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(=O)O)C3=O)cc2)c1 +Cc1cc(O)cc2cc3c(c(O)c12)C(=O)CCC3O +CCCCN1C(=O)N(Cc2cccc(C(=O)Nc3ncc[nH]3)c2)C(Cc2ccccc2)C(O)C(O)C1Cc1ccccc1 +Clc1ccc(-c2n[nH]c(N3CCc4ccccc4C3)c2-c2ccncc2)cc1 +CC(NC(=O)C(O)C(O)C(=O)N1CCCCC1c1cccc(Cl)c1)c1ccc(-n2cccn2)cc1 +O=C1NC(Cc2ccccc2)C(=O)N1CC(CCN1CCC(c2ccccc2)CC1)c1cccc(Cl)c1 +CC(=O)N1CCC(Nc2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)CC1 +CC(c1nnc2c(F)cc(-c3cnn(C)c3)cn12)n1ccc2ncccc2c1=O +CCn1c(CCc2ccccc2Cl)nc(N2CCNCC2)cc1=O +CC(C)(Cc1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc2nonc2c1)C(=O)O +CN(C)CCNC(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +O=C(NC(CCO)c1ccc(F)cc1)C1SCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +CC(=O)Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1 +COCCNC(=O)c1c(NC(=O)c2ccccc2Cl)sc2c1CCC(F)(F)C2 +O=C(Nc1sc(N2CCN(CCc3ccccc3)CC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +CCn1c2ccccc2c2cc(NS(=O)(=O)c3cc(OC)ccc3OC)ccc21 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4ccc(Br)cc4)nc31)C(O)C2O +CC(C)c1nc2c(c(Nc3ccc(C(F)(F)F)nc3)n1)CCN(c1ncccc1S(C)(=O)=O)CC2 +COc1ccnc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)c1 +O=C(Nc1cccc2c1C(=O)c1c(-c3ccc(C(=O)N4CCCCC4)s3)n[nH]c1-2)NN1CCOCC1 +COc1ccc2c(c1)c(CC(=O)NOCc1ccc([N+](=O)[O-])cc1)c(C)n2C(=O)c1ccc(Cl)cc1 +Cc1n[nH]c(-c2cn3c(n2)-c2ccc(-c4cnn(CCO)c4)cc2OCC3)n1 +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)NC(C)C)c1ccc2occc2c1 +CNC(=O)C(Cc1c[nH]cn1)NC(=O)CN(CCCc1ccccc1)CC(=O)O +COc1ccccc1-c1noc(-c2ccc(-c3ccccc3C)c(C(F)(F)F)c2)n1 +NC(=O)CNC(=O)N1CCC(CC(=O)N2CCC(C3c4ncc(Br)cc4CCc4cc(Cl)cc(Br)c43)CC2)CC1 +O=C(Cn1cnc2cccc(C(F)(F)F)c2c1=O)C1NCCC1O +COc1cc(C2OCCc3nc(SCc4c(F)cccc4Cl)n(-c4ccc(F)cc4)c32)ccc1F +COc1ccccc1NC(=O)N(Cc1ccccc1)C(C)c1nc2ccccc2c(=O)n1-c1cc(C)ccc1OC +CN(C)C(=O)CC1(NC(=O)c2cc(OCC(F)(F)F)c(Cl)cn2)COC1 +COc1cccc(OC)c1-c1ccc(CC(Nc2cccc(S(=O)(=O)N3CCCC3)c2)C(=O)O)cc1 +COc1ccc(NC(=NC(=O)c2ccc(N(C)C)cc2)NC2CCCCN(CC(=O)N3CCCC3)C2=O)cc1 +N#Cc1cccc(N2CCN(CCN3CCC(C(F)(F)F)CC3)C2=O)c1 +O=C(C1CC(n2cc(-c3ccc(F)c(F)c3)nn2)CN1C(=O)CCCc1ccccc1)N1CCCC1 +CCCNc1nc(N(CCO)CCO)nc2c(NCCC)nc(N(CCO)CCO)nc12 +O=C(NC(CO)c1ccc(F)c(Cl)c1)N1CCc2cnc(NC3CCOCC3)nc2C1 +NCCCN(CCCN)C(=O)COc1ccc2sc(CNc3nncc(-c4c(Cl)cccc4Cl)n3)nc2c1 +CC(C)CC(CC(=O)NO)C(=O)NC(CC(C)C)C(=O)NC(C)C=O +CCOC(=O)CCc1ccc(-c2ccc(OC)cc2)n1-c1ccc(C(N)=O)cc1 +c1ccc(-c2cc(NCc3ccco3)nc(-c3ccccn3)n2)nc1 +COc1ccc(Oc2cc(C)c(-c3csc(NC(=O)c4ccncc4)n3)c(C)c2)cc1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc(N4CCN(C)CC4)cc3)nc12 +CN(CCO)C(=O)c1ccc(C(=C2CCN(Cc3cscn3)CC2)c2cccc3cccnc23)cc1 +CC(CO)NC(=O)CCCC=CCC=CCC=CCC=CCCCCc1cccc(Br)c1 +COc1cc(CNCCc2ccccc2)cc(Br)c1OC1CCCC1 +CN1C(=O)N(CC(COc2ccc(-c3ccc(C#N)cc3)cc2)N(O)C=O)C(=O)C1(C)C +Cc1cc(-c2cc3c(NCc4cccnc4N(C)S(C)(=O)=O)c(C#N)cnc3[nH]2)ccn1 +Nc1ccccc1NC(=O)c1ccc2nc(N3CCNCC3)ccc2c1 +COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 +CCc1nccc(-c2ccc(C(=O)N3CCN(CC)C(C)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +COc1ccc(NC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NCC2(c3ccccc3)CCCCC2)cc1 +NC1(c2ccc(-c3nc4c5cccc(-c6ccc(CO)cc6)c5nn4cc3-c3ccccc3)cc2)CCC1 +CCN(CC)C(=O)c1ccc(C(=O)NC)c(NC(=O)c2nc(C(C)(C)C)ncc2Nc2cncnc2)c1 +Nc1ncc(Cc2ccc([N+](=O)[O-])cc2)c(N)n1 +COC(=O)C=CCCC1C(c2ccccc2)CC2CCC1N2C +O=C(COc1cccc(NC2CCOCC2)c1)NCC(O)CN1CCc2ccccc2C1 +CN(C)C(=O)Nc1cc(Oc2cc(F)c(NC(=O)N3CCN(C4CCOCC4)C3=O)cc2Cl)ccn1 +C=CCOc1ccc(CCCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 +COc1ccc(-c2cc3c(C)nc(N)nc3n(CC(C)(C)O)c2=O)cn1 +CC(C)(C)c1cc(Cl)ccc1OCC1CN(C(=O)C(=O)O)C1 +CN1CCC(c2cc3c(-c4cncc(NCc5cccnc5)n4)ccnc3[nH]2)CC1 +COc1ccc(NS(=O)(=O)c2ccc(N=Nc3cc(C)c(O)c(C)c3)cc2)nc1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(NCCN2CCN(C)CC2)nc1 +Oc1ccc2c(c1)C13CCN(CCc4ccccc4)C(C2)C1Cc1cc2ccccc2nc1C3 +O=C(NC(CO)c1ccc(F)cc1)c1ccc(-c2c[nH]c3ncccc23)s1 +COc1ccc(C(C)(NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)Nc2cccc(Oc3ccccc3)c2)cc1 +Cc1cccc(NC(=O)Nc2ccc(-c3c(C)nc4ccnn4c3N)cc2)c1 +Cn1nc(C(F)(F)F)cc1C(=O)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +CCc1cccc(N(C)C(=N)Nc2cc(SC)cc(CC)c2Br)c1 +CC(C)(C)n1nc(-c2ccc3ccccc3n2)c(C(N)=O)c1N +COCCOc1cc2ncnc(NC3=C(Cl)C(=O)C=C(OC)C3=O)c2cc1OC +COc1cc(C(F)(F)F)cc(S(=O)(=O)c2cccc(N)c2C#N)c1 +Cc1nc2cccc(C(=O)O)c2n1Cc1ccc(-n2cccc2C(=O)O)cc1 +CC1CCCN1c1cccc(Nc2cc(-c3cccc(OCCN4CCOCC4)c3)nn3ccnc23)n1 +NCC1CCCN(c2ccncc2-c2cc3c(-c4ccccc4F)n[nH]c3cn2)C1 +O=C(COc1ccccc1)NS(=O)(=O)c1ccccc1-c1ccc(CN2C(=O)c3ccccc3CCc3ccccc32)cc1 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+O=C(Cn1c(=O)ccc2cc(F)c(F)cc21)Nc1scc(Br)c1-c1ncn[nH]1 +Cc1nc2cnc3ccc(C#CCNC(=O)c4cccn(Cc5ccccc5)c4=O)cc3c2n1C(C)C +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cccnc1 +CNCC(O)Cn1c2ccc(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +O=C(CCc1ccc(Nc2nccc(Nc3cc(C4CC4)n[nH]3)n2)cc1)NCCCN1CCCCC1 +CC(C)(C)CC(=O)Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1 +CCOCCn1cc(C(=O)NCc2ccc(Cl)cc2Cl)ccc1=O +O=C(O)CCCN1CC(C(=O)O)Oc2c(CCc3ccc(OCCCCc4ccccc4)cc3)cccc21 +Cc1ccccc1C(=O)NCC1(c2ccccc2)CCN(C)CC1 +NCCCCC(NC(=O)OCc1ccccc1)C(=O)c1noc(Cc2ccc(C(=O)NCCc3cccs3)cc2)n1 +O=C(CCl)OCCn1c(=O)oc2cc3ncnc(Nc4ccc(N5CCOCC5)c(Cl)c4)c3cc21 +Nc1nnc(-c2ccc3[nH]cc(-c4nccc(N5CCCC(O)C5)n4)c3c2)o1 +NC(=S)Nc1cccc(OCCCCCN2CCN(c3cccc4ccccc34)C2=O)c1 +Cn1c(=O)c(Oc2cccc(F)c2)cc2cnc(NC3CCOCC3)nc21 +C=CCCC(CC1OC(=O)C1CCCCCC)OC(=O)C(Cc1ccccc1)NC=O +O=C(O)CCCCC(=O)N1CC(C(=O)O)Oc2c(NC(=O)c3ccc(OCCCCc4ccccc4)cc3)cccc21 +Cn1ncc(NC(=O)c2nc(-c3ccnc(F)c3)sc2N)c1N1CCCC(N)CC1 +Oc1ccc(C2=NCCN2)cc1-c1cc2ccc(C3=NCCN3)cc2o1 +C1=C(c2ccccn2)CN(c2nnc(N3CCC(N4CCCCC4)CC3)s2)CC1 +CCC1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(F)c(F)cc3nc2-1 +Oc1ccc(C2Sc3cc(O)ccc3OC2c2ccc(N3CCCNCC3)cc2)cc1 +O=C(NCC1CCOCC1)c1cnc(Nc2cc(Cl)cc(Cl)c2)cc1C1CC1 +CCN(C(CC(C)C)C(N)=O)S(=O)(=O)c1ccc(Cl)cc1 +CCCOc1cc(Cc2c(N)nc(N)nc2CC)ccc1OCc1cc(OC)c(OC)c(OC)c1 +Cc1cc(Nc2nc(Cl)cn(C(C)C3CC3)c2=O)c(C)nc1OC(F)F +CCNC(=O)c1cc2c(-c3cc(OCCN(CC)CC)c(Cl)cc3Cl)nc(N)nc2s1 +COc1ccc2cc1COCC=CCOCc1cc(ccc1OCCN1CCCC1)Nc1nccc-2n1 +COCCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN1CC[S+]([O-])CC1 +CCOc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c[nH]c2c1 +COC(=O)c1ccc2cc(OC(=O)c3ccc(NC(=N)N)cc3)ccc2c1 +CCN(CC)C(=O)C1CCCN1C(=O)NCc1ccc(C(=O)N2CCCCc3ccccc32)cc1C +COc1cc(C(F)F)ccc1-c1cccn2nc(Nc3ccc(C4CCNCC4)cc3)nc12 +COCC1CCCN1CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +COc1c(-c2ccc3cc(NS(C)(=O)=O)ccc3c2)cc(-n2ccc(=O)[nH]c2=O)cc1C(C)(C)C +O=C(c1ccccc1C(F)(F)F)N(CC1CCC1)C1CCNC1 +O=C(NCC(O)C(F)(F)F)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 +FC(F)(Cl)Oc1ccc(Nc2nnc(-c3cccnc3CCc3ccncc3)o2)cc1 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+CCc1ncccc1Oc1cc(CCCC(C)(C)O)cnc1NC(=O)NC +COc1cc(OC)cc(N(CCNC(=O)C2CCCN(C)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1noc(C)c1CCC1CCN(S(=O)(=O)CC2(N(O)C=O)CCS(=O)(=O)CC2)CC1 +CC(C)Oc1cccc(-c2c[nH]c3ccc(-c4nnc(N)o4)cc23)n1 +CC1(O)CCC2C(C(CCO)CCC2(C)C#N)C1C#N +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)c4cnsc4)nc23)N1 +CCOCCOC1CCN(S(=O)(=O)CC2CCC(N(C)c3ncnc4[nH]ccc34)CC2)C1 +CNC1CCN(c2cc(NCc3ccccc3)nc(N)n2)C1 +COCCN(Cc1csc(C(=O)Nc2c(OC)cc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)c1Cl)C1=NCCO1 +COc1ccccc1C(c1ccccc1OC)N1CCN(CCCCNC(=O)C=Cc2ccccc2)CC1 +CCCCN(NC(=O)C(CCC)N1CCC(CCC)(NCCCC2CCCCC2)C1=O)C(=O)OCC +NC(CC(=O)N1CCCC1COc1ccnc(C(F)(F)F)n1)Cc1cc(F)c(F)cc1F +CN(C)CCc1c(-c2ccccc2)[nH]c2ccncc12 +O=S(=O)(c1ccccc1)c1c(OCCCc2ccc(O)cc2)no[n+]1[O-] +CN(CCC#N)c1cnc(C(=O)NCC(C)(C)c2ccccc2)cn1 +CC(C)(C)c1ccc(CN2CCN(C(=O)C=Cc3ccc(Br)cc3)CC2)cc1 +CCOc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc(N)c1N=O +COc1ccc(-c2cnc3cc(OC)c(OC)cc3c2)cc1 +Cn1c(C(=O)N2CCn3cc(C(=O)NO)cc3C2)cc(Cl)c1Cl +O=C1N(Cc2ccnc(Br)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)Nc2nc(CC(=O)O)cs2)n1 +CN(CCc1cn(-c2ccc(F)cc2)c2ccc(Cl)cc12)CCN1CCNC1=O +CC1(C)CC=C(c2ccc(C#N)cc2)c2cc(C#Cc3ccc(C(=O)O)cc3)ccc21 +COc1ccc(Nc2cc(Nc3cccc(OC(F)F)c3)nc(NC3CCCCC3)n2)cc1 +COc1ccccc1CN(C)CC1CC1c1cc(F)ccc1OC +COc1ccc(CC(O)CC(Cc2ccccc2)C(=O)NC2c3ccccc3CC2O)c(OC)c1 +Oc1ccc(-c2cncc(-c3ccc(O)cc3)c2)cc1 +CC(C)C(Sc1nc(S)c2cnn(-c3ccccc3)c2n1)C(N)=O +Cc1ccc2[nH]c3c(NCCN(C(C)C)C(C)C)ncnc3c2c1 +Cc1nn(-c2ccc3onc(N)c3c2)c2c(=O)n(-c3ccc(-c4ccccc4CNC(C)C)cc3)cnc12 +Cc1n[nH]c(C)c1CN1CCN(c2cccc3[nH]c(-c4ccc(C(C)(C)C)cc4)nc23)CC1 +COCCc1ccc(Cl)c(CN(C(=O)C2CNCCC2c2ccc(N3CCC(Oc4c(Cl)cc(C)cc4Cl)C3)nc2)C2CC2)c1 +CN(Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CCc1ccccn1)c1ccccc1 +Cc1cc(C#N)cc(C)c1Nc1nc(Nc2ccc(C#N)cc2)ncc1C#N +CCOC(=O)C1(Cc2ccccc2)c2c(cnc3c(-c4ccc(C(F)(F)F)cc4)cnn23)CN1C +CCNc1nc(OCCc2c[nH]c3ccccc23)nc2c1ncn2C1OC(CO)C(O)C1O +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCCC(N(CCO)CCO)CC1 +CC(c1c[nH]c2ncccc12)c1nnc2ccc(-c3cnn(C)c3)nn12 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+CN(CC1CCCO1)C(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +Cc1ccc(C(=O)Nc2cc(OCCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(NCC3CCOC3)nc12 +NS(=O)(=O)c1ccc(NC(=S)NN=C2C(=O)Nc3ccc([N+](=O)[O-])cc32)cc1 +CN1CCc2nc(C(=O)Nc3ccncc3CNC(=O)c3ccc(Cl)s3)sc2C1 +CCc1oc2ccc(OC)cc2c1C(=O)c1cc(Br)c(O)c(Br)c1 +COc1cccc(CNCCCNc2ccnc3cc(Cc4ccc(C#N)cc4)ccc23)c1O +CCC(c1ccccc1)n1cc(NC(=O)c2n[nH]c3ccccc23)cn1 +COc1n[nH]c2cc(NC(=O)NC3CN(C)CC3c3ccccc3C)ncc12 +COc1ccccc1-c1nnc(SCCCN2CCc3ccc(-c4cc(C)on4)cc3CC2)n1C +O=C1CCC2=C(C3Oc4c(O)ccc5c4C34CCN(CC3CC3)C(C5)C4(O)C2)N1CC1CCCCC1 +CC(C)(C)c1ccc(CNC(=O)C(C)(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(-c2cccc(C(F)(F)F)c2)cc1F +Cc1cc(C)cc(-c2[nH]c3ccc(C(=O)N4CCCCC4)cc3c2CCNCCCCc2ccc(NS(C)(=O)=O)cc2)c1 +CNCCC(c1ccccc1)n1c(=O)n(C2CCCCC2)c2ccccc21 +O=C(O)C1CCCC(NC(=O)C2(CS)CCCCC2)C1 +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CCC(C(O)C(F)(F)F)C1 +[H]C1([H])OC(C)(C)C(=O)N(c2cc(-c3cc(Cl)c4c(N)ncnn34)ccc2C#N)C1([H])[H] +CC(NC(=O)c1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1)C(=O)O +CCCc1cncnc1-c1ccc2c(c1)CCC(C)N2C(=O)c1ccc(O)cc1O +CN(C(=O)C(F)(F)F)C(C#CCN1CCCC1)c1ccccc1 +O=C1N=C(NC23CC4CC(CC2C4)C3)SC12CCCC2 +NS(=O)(=O)c1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)c(I)c1 +COCCOCc1ccc2cc(CCn3ncc4c3nc(N)n3nc(-c5ccco5)nc43)ccc2n1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCCN5CCCCC5)s4)nc23)N1 +CC1(C)CCCN(c2ncnc3[nH]cc(-c4cccc(C#N)c4)c23)C1 +Nc1nc(NN=Cc2ccc(CCC(=O)O)cc2)nc2c1ncn2C1OC(CO)C(O)C1O +O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)C1CCC1 +O=C(NC1CSSCC(C(=O)O)NC(=O)C2CCCN2C(=O)C(CO)NC1=O)c1cccc2ccccc12 +CCc1cc(-c2ccccc2)cc(CC)[n+]1CC(=O)OCc1ccc(S(N)(=O)=O)cc1 +COc1cccc(-c2cc(F)c(Nc3ncccc3C(=O)O)c(F)c2)c1F +CN1CCN(c2ccc(C(=O)NC3CCC(CCN4CCC(c5cccc6c5CCO6)CC4)CC3)cc2)CC1 +Cc1ncc(Cl)cc1C(=O)NC1CCC(CN2C(=O)C(C)(C)c3ccccc32)CC1 +O=C(O)Cc1ccc2oc(-c3ccc(NC(=O)C=Cc4ccc(F)c(Cl)c4)c(F)c3)nc2c1 +NC1CCN(C(=O)C2CCCCN2S(=O)(=O)c2ccc(-c3ccco3)cc2)C1 +O=C(c1cc(=O)c2cc(O)ccc2[nH]1)N1CCC(Cc2ccc(F)cc2)CC1 +CC(Nc1c(Nc2ccncc2)c(=O)c1=O)C1CCCCC1 +CC1(CNCc2ccc(-c3ccccc3S(=O)(=O)N3CCCC3)cc2)COC1 +CC(C)(CO)CNCc1ccc(Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)nc1 +N#Cc1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COCCO3)nc2=O)cc1 +COc1cccc(C=NNc2nc(N)c3ncn(C4OC(CO)C(O)C4O)c3n2)c1 +O=C(O)C=Cc1ccc(Oc2c(C(=O)c3ccccc3C(F)(F)F)sc3cc(O)ccc23)cc1 +O=C(NC(=S)Nc1sc2c(c1C(=O)O)CC1(CCCC1)OC2)c1ccccc1 +CCOCCOc1ccn2ncc(C(=O)NCCCN3CCN(c4ccccc4OC)CC3)c2c1 +COc1cc2nc(N(C)CCCCCCN(C)C(=O)c3ccc(CN4CCSC4)cc3)nc(N)c2cc1OC +COc1ccc(Nc2ccc(Oc3ncccc3C3CCN(C(C)=O)CC3)cc2)nc1 +Cc1nc2cccc(-c3cc4c([nH]3)CCN(CO)C4=O)c2nc1NC(C)(C)C +O=C(O)Cc1cn(CC(O)CN2CCCCC2)c2ccccc12 +CS(C)(=O)=NC(=O)c1cnc(N)c(C#Cc2cccc(NC(=O)c3ccc(Cl)cc3)c2)c1 +COc1c(C(=O)NC2CCN(C3C4CCCC3CCC4)CC2)cc(Br)c2ccccc12 +Cc1c(C#N)c(-c2ccc(C#N)cc2)c(C)n1Cc1ccccc1 +CCOC(=O)c1sc2c(OC)c(C)c(C)c(C)c2c1Nc1cc(OC)c(OC)c(OC)c1 +CCC(NC(=O)c1ccc(Sc2ccc(N)cc2)c(Nc2ncnc3nc(C(C)C)ccc23)c1)c1ccccc1 +CC(=O)c1cc(NC(=O)NC2CCCCC2CN2CCCC(Cc3ccc(F)cc3)C2)cc(C(C)=O)c1 +N#Cc1c(COc2ccc3c(c2)C2CN(C(=O)C4CCCCC4)CC(=O)N2CC3)no[n+]1[O-] +Cc1ccccc1COc1cc(-n2cnc3ccccc32)sc1C(N)=O +CCCN(CCC)CCc1ccc(OCCc2ccccc2)c(O)c1 +CC(C)CCN(C)C(=O)c1c(F)cccc1OCC(=O)NC(CO)Cc1ccccc1 +O=C1NCN(c2ccccc2)C12CCN(C1(c3ccccc3)CCCCC1)CC2 +COc1ccc(-c2cc3cc(C)ccc3c(N)n2)cc1OC +CNC(=O)OC(C)C=CC(=O)NC1CCC(CC=C(C)C=CC2CC3(CO3)CC(C)(C)O2)CC1 +COc1cccc2c1C(NCC(C)(C)c1ccccc1)=NC2=O +CCc1c2c(n(C)c1C)CCCC2=NOC(=O)Nc1ccc(C(C)=O)cc1 +CNc1cc(N2CCNCC2)ccc1S(=O)(=O)c1ccccc1 +CC(C)CNC(=O)c1ccc(-c2ccc(-c3occc3CO)cc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +CCOC(=O)c1cc(=O)c2cc(F)cc(NC(=O)c3ccc(OC)cc3)c2o1 +Oc1cccc(-c2cc(N3CCOCC3)nc(NCCc3cccnc3)n2)c1 +CCS(=O)(=O)c1ccc(OC2CCN(C)CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +CC1(C)C(C(=O)N=C(N)N)C1c1cc(Cl)cc(Cl)c1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cncc(NS(=O)(=O)C(C)C)c3)NC(=O)NC1=O)C2 +CC1CN(CCOc2ccc(C3Oc4ccc(O)cc4SC3c3ccc(O)cc3)cc2)CC1C +N#CC1CSCN1C(=O)CN(N)C1CCN(CC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 +CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Nc3ncnc4c(N)ncnc34)c2)c1 +COc1cc(OC)c2c(C)[n+](-c3ccc(C(C)C)cc3)c(C)cc2c1 +C#Cc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1 +O=C(NCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)c1cnc(Cl)s1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(NC3CN4CCC3CC4)c2c1=O +COn1c(-c2ccc(C)cc2)cc2cc3c(cc21)C(=O)NC3=O +CCOCCn1c(=O)nc(N2CCN(CCO)CC2)c2nnc(-c3ccc(OC)nc3)cc21 +CC1COc2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc2N1C(=O)Nc1ccccc1 +COC(=O)c1[nH]c(C(C)(C)C)cc1NC(=O)Nc1ccccc1Cl +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cc(-c2ccccn2)ccc1Cl +Cn1cnc2cc(-c3ccc(C(C)(C)O)nc3)nc(Nc3ccccn3)c2c1=O +CCCOc1c(-c2csc(-c3cc(C(=N)N)sc3SC)n2)cnn1-c1ccccn1 +Cc1ccc(S(=O)(=O)n2ccc(NC(=O)c3ccccn3)c2)cc1C +COC(=O)c1cccc(CN2C(=O)C3(N=C2N)c2cc(Br)ccc2CC32CCC(OC)CC2)c1 +CCCc1cc(C)[nH]c(=O)c1CNC(=O)c1cc(-c2ccc(N3CCN(C(C)C)CC3)nc2)cc2c1cnn2C(C)C +CCCCCCCN(CCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)C(=O)Nc1ccc(F)cc1F +COc1c(C(=O)NC2CCN(C3CCCCC3)CC2)cc(Br)c2ccccc12 +CCS(=O)(=O)c1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2CN2CCOCC2=O)cc1 +O=C(Nc1ccccc1Oc1ccc(C(=O)O)c(C(=O)O)c1)c1cc(Cl)ccn1 +CNc1ccc(Cl)cc1C(=O)NC1CCN(Cc2ccc3c(c2)OCO3)CC1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCC(NCC2CCCCC2)CC1 +Cc1cccc(S(=O)(=O)N(C)C(CNC(=O)CC2CC(c3ccc(C(=N)N)cc3)=NO2)C(=O)O)c1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2OCC2(F)COC2)c2cc[nH]c2c1=O +CC=C1C2C=C(C)CC1(N)CC(NCCCCCCCNc1c3c(nc4ccccc14)CCCC3)C2(C)C +O=C(C1CCN(S(=O)(=O)c2cccc3cccnc23)CC1)N1CCn2c1nc1ccccc12 +N#Cc1ccc(Oc2ccc(-n3cc(C(O)(C(N)=O)C(F)(F)F)c4ccccc43)cc2)cc1C(F)(F)F +C=CCN1CC(C)N(C(c2ccccc2)c2ccc(C(=O)N(CC)CC)cc2)CC1C +CN(C)CCC1CCN(c2cc(C#N)c(C#N)cc2[N+](=O)[O-])CC1 +COc1ccc2c(c1)N(CCN1CCC(NCc3ccc4c(n3)NC(=O)CO4)CC1)C(=O)CO2 +CCC1C(C)OCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +Cc1nc2c(c(-c3ccccc3)n1)CCN(C(=O)c1cccc(Cl)c1Cl)C2 +COc1ccc2nc(NC3=NCC4(CN5CCC4CC5)N3)sc2c1 +Cc1c2c(n(-c3ccc(Cl)cc3Cl)c1-c1ccc(C(F)(F)F)cc1)CCN(C1CCCCC1)C2=O +CC(C(=O)OC1C[N+]2(CCc3ccc(F)cc3)CCC1CC2)(c1ccccc1)N1CCCCC1 +CCS(=O)(=O)c1ccc(NCC2CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +COc1ccc(NC(=O)C(=O)Nc2ccccc2OC)c(C(=O)Nc2ccc(N3CCOCC3=O)cc2)c1 +c1ccc(C2CN3CCCC3c3cc(OCCCN4CCCCC4)ccc32)cc1 +CC1CN(Cc2ccc(-c3cccnc3S(=O)(=O)N3CCC(Nc4ccccc4F)CC3)cc2F)CC(C)N1 +O=C(NC1CCN(C(c2cnccn2)c2ccc(F)cc2F)CC1)C1CCCCC1 +CCNc1ncc(-c2ccc(Oc3ncc(NC(=O)Nc4cc(C(F)(F)F)cnc4-c4ccc(C)cc4)cn3)cc2)s1 +CCN1CCN(c2ccc(Nc3ncc4scc(-c5cccc(NS(C)(=O)=O)c5)c4n3)cn2)CC1 +CSc1cnc(OCCOc2ncnc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2-c2ccc(C)s2)nc1 +CCNc1cc(-c2cc(C(F)(F)F)nc3c(-n4cnc(-c5cnn(C)c5)c4)cccc23)ccc1C(N)=O +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NCCc1ccccc1 +O=C(c1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)cc1)N1CCCC1 +Cc1cnc2c(C(F)(F)F)cccc2c1-c1cccc(Oc2cc(F)cc(S(C)(=O)=O)c2)c1 +CC1CCN(C(=O)C(Cc2cccc(C(=N)N)c2)NS(=O)(=O)c2cccc(NC(=O)CCN)c2)CC1 +COC1OC2(c3ccc(F)cc3)CCCC3CCCCC31OO2 +CN(C)CCCNc1nc2ccccc2c2[nH]c3ccccc3c12 +CC1(C)CC(N)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C1 +O=c1[nH]c2ccccc2n1C1CCN(C2CCN(Cc3ccccc3C(F)(F)F)CC2)CC1 +Cc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)NC4CN(C)C4)cc3Cl)nc1-2 +CCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 +CCOC(=O)CCC1=C(n2ccc3ccccc32)c2ccccc2C(=O)C1=O +CN1C2CCC1C(C(=O)Oc1ccc(Cl)cc1)C(c1ccc(Cl)cc1)C2 +Nc1ccccc1NC(=O)c1ccc(C(C(=O)NCc2ccccc2)C(=O)NCc2ccccc2)cc1 +Cc1cc(Cl)nc(C)c1C(=O)NCCC(C)N1CCC(N2C(=O)N(C3CCCCC3)CC2c2ccccc2)CC1 +Nc1nc2ccc(O)nc2n1C12CC3CC(CC(C3)C1)C2 +O=C(NCc1ccc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cn1)N1Cc2ccncc2C1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)C1CCOc2c1ccc[n+]2[O-] +Cn1c(CNc2cccc(C(=O)NCc3ccccc3)c2)nnc1-c1ccncc1 +Cc1nnc(CNC(=O)C(O)c2ccc(-c3noc(-c4onc(-c5ccccc5)c4C(F)(F)F)n3)cc2)o1 +O=C(NCCCN1CCC(Cc2ccccc2)CC1)c1ccc2cc(Br)ccc2c1 +N#Cc1cc(-c2ccccc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1 +Cc1cc(Nc2cc(N3CCOCC3)nc(Sc3ccc(NC(=O)C4CC4)cc3)n2)n[nH]1 +c1ccc2c(c1)CCN(CCCc1nc3ccccc3s1)C2 +O=C(NC1CCOCC1)c1ccc(OCc2conc2-c2ccc(Cl)cc2)nc1 +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c(F)cc(C3=CCOCC3)cc12 +O=C(C1CC(N2CCN(c3ccc(C(F)(F)F)cn3)CC2)CN1)N1CCC(F)(F)C1 +Cc1cc(=O)oc2c1ccc1oc(=N)c(C(=O)N3CCOCC3)cc12 +CCc1ccc(C2CC(NC(=O)N(C)c3ccccc3)CN(C(=O)C3CCCC3)C2)cc1 +O=c1c2ccccc2nnn1CCN1CCN(c2cccc3ccccc23)CC1 +COc1cc(-c2cnn(CCN3CCN(C)CC3)c2)ccc1Nc1ncc2ccnc(NC3CCCCC3)c2n1 +Cc1cc(C(=O)N2CCc3cccn3-c3ccccc32)ccc1CNC(=O)N1CCCC1C(=O)N(C)C +COc1ccc(NS(=O)(=O)c2ccc(-n3cccn3)cc2)cc1N1CC(C)NC(C)C1 +CN(C)C(=O)c1cn(-c2cc3c(=O)n(NS(C)(=O)=O)c(=O)[nH]c3cc2C(F)(F)F)cn1 +CC(=O)Oc1ccc2c(c1)C1c3cc(OC(C)=O)ccc3C(C2)N2CCCC12 +Cc1nc(C)n(-c2cc(C3CC3c3nc4ccccc4n3C)nc(C3CC3)n2)n1 +CCCNS(=O)(=O)c1c(C(N)=O)[nH]c2ccc(Br)cc12 +O=S(=O)(c1ccccc1)N(CC(F)(F)F)c1ccc(C(O)(c2ccccc2)C(F)(F)F)cc1 +CNC(=O)c1ccccc1Nc1nc(Nc2ccc3c(c2OC)CCCC(N2CCN(CCO)CC2)C3)ncc1Cl +N=C(N)NC(=O)c1ccc2c(c1)C(F)c1ccccc1-2 +CCc1ccc(C2Nc3ccccc3-n3c(-c4ccccc4)c4c(=O)n(C)c(=O)n(C)c4c32)o1 +Cn1c(SCCCN2CCOC(c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccc(-c2ncco2)cc1 +CC(C)CN1CCc2c(cccc2Oc2ncccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)C1 +Cc1cc(C=CC#N)cc(C)c1Nc1ccc(F)c(Nc2ccc(C#N)cc2)n1 +CC1(NS(=O)(=O)c2ccccc2-c2ccc(-c3ccc(N)nc3)c(F)c2)CCC1 +Cn1ncc(NC(=O)c2ccc(F)c(-c3c(F)cc(C(CO)CO)cc3F)n2)c1C1CCC(N)C(F)CO1 +COc1cccc(-c2cn(C)c3c(NN=Cc4ccncc4)ncnc23)c1 +O=C(O)CCCCc1nc2cc(C3=NOC4(C3)Cc3ccccc3C4)ccc2c(=O)n1-c1ccc(F)cc1 +Cc1cc(C)c(-n2c3ncccc3n3c(CN(CC4CC4)CC4CC4)c(C)nc23)c(C)c1 +O=c1c(-c2ccccc2)c2ccccn2c(=O)n1CCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +COc1cc(OC2CCN(C(C)=O)CC2)ccc1CC(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2NCC2CC2)c2cc[nH]c2c1=O +COc1ccccc1-c1ccc(CC(NC(=O)C2(S(=O)(=O)c3ccccc3)CCN(c3ccccc3)CC2)C(=O)O)cc1 +COc1ccc(C=C2C(=O)N(C(=O)c3ccccc3O)N=C2C)cc1OC +CC(C)CNC(=O)c1cnc(NCCCN2CCCCC2C)nc1NCC1CCCCC1 +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1Cc1cccc(NS(C)(=O)=O)c1 +COc1ccc(NC(=O)c2ccc(C)c(Nc3ncnc4cnc(-n5cnc(C)c5)nc34)c2)cc1C(F)(F)F +CCN(CC)CCCOc1ccc2nc3n(c(=O)c2c1)CCC3 +O=C(O)C1(CCCCn2cnc3c2NC=NCC3O)Cc2ccccc2C1 +CC(C)N(CCNC(=O)C1c2ccc(OCc3ccccc3)cc2CCN1C(=O)Cc1ccccc1)C(C)C +CCOc1ccnc2ccc(C#CCNC(=O)c3cccn(Cc4ccc(F)c(F)c4)c3=O)cc12 +COc1cc(OCc2csc(Cl)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccncc3)c2)s1 +O=C(C1CCCN(c2ccc3nc(-c4cnn(-c5ccccc5)c4)[nH]c3n2)C1)N1CCCC1 +Cc1nn(C)cc1-c1nc2c(Oc3ccc(C(=O)Nc4ccccc4)cc3)ccnc2[nH]1 +COc1cc(CCNC(C)COc2c(C)cc(Br)cc2C)ccc1O +Cc1nnc(NC(=O)c2cc(C3CC3NCC3CC3)c(C)s2)s1 +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)N1CCOCC1)c1ccc(F)cc1F +CNC(=O)c1cnc(C(=O)CCc2ccc(Oc3ccccc3)cc2)o1 +CCn1cnc2c(-c3ccc(F)c(-c4ccc(S(=O)(=O)CC)cc4)c3)cnnc21 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCCCCC(=O)NO +Cc1ccc(C(=O)Nc2cccc(C(C)(C)C)c2)cc1Nc1ncnc2c(N)nc(N3CCN(C)CC3)nc12 +O=C(Nc1cnccc1Cl)N1CCN(Cc2cccc(Oc3ccc(F)cc3)c2)CC1 +Cc1ccc2c(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c[nH]c2c1 +C[S+]([O-])c1c(C(=O)NN2CCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +OC1(c2ccc(Cl)cc2)c2cccc3cccc(c23)C2=NCCCN21 +CC(C)(C)OC(=O)N1Cc2[nH]c3ccccc3c2CC1C(=O)NCCCCCCNc1c2c(nc3ccccc13)CCCC2 +Cc1cc2c(c([N+](=O)[O-])c1)N(C)C(=O)c1cccnc1O2 +O=C(Nc1cccc(-c2nc3c(N4CC5CCN(Cc6ccccc6)C5C4)ncnc3o2)c1)c1ccccc1 +CN1CCC23Cc4c(c5ccccc5n4C)CC2(Cc2ccc(O)cc23)C1 +CC(C)n1cnc2c(NCc3ccc(-c4ccc(F)cc4)s3)nc(NC3CCC(N)CC3)nc21 +COc1ccc(Nc2nn3c(-c4ccncc4)nnc3s2)cc1 +Cn1nc(C(F)(F)F)cc1-c1cnc2[nH]c(-c3c(F)cccc3F)cc2c1 +O=C(C=Cc1ccco1)NC(=S)Nc1cccc(-c2nc3ccccc3o2)c1 +O=C(O)c1ccc(-c2cccc3c(CCCOc4cccc5ccccc45)c(C(=O)O)nn23)cc1 +COc1cc2c(cc1C(C)NCCc1ccccc1)CCC(C)(C)O2 +CC(C)(C)c1cn(C2=NCC(=O)N3CCc4c(cccc4C4CCCO4)C3=C2)cn1 +CCc1ccc(S2=NS(=O)(=O)c3cc([N+](=O)[O-])ccc32)cc1 +CC(=O)N1CCN(c2ncnc(C)c2C#Cc2cnc(C)c(NS(=O)(=O)c3ccc(F)cc3F)c2)CC1 +CCCCc1nn(-c2ccccc2C(F)(F)F)c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC#N)cc1 +Cn1cnc2ccc(N3CCCC(OCC(O)CN4CCc5ccccc5C4)C3)cc21 +COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cccc(Cl)c1F)C(=O)N2 +CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1cccc2ccccc12 +COc1cccc2c1C(CCCN1CCN(c3cccc(C(F)(F)F)c3)CC1)=CCC2 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(C2CCOCC2)c(-c2cncnc2)c1 +COc1ccc(-c2cc(OC)cc(C(C)C#Cc3c(C)nc(N)nc3N)c2)cc1 +C[n+]1ccc(Nc2ccc(C(=O)c3ccc(N(CCO)CCO)cc3)cc2)c2ccccc21 +COC(=O)C1CC(OC(C)=O)C(=O)C2C(C)(CCC3CCOC3)C(C(=O)O)CCC12C +Cn1cc(Cc2cn(CCCC(=O)N3CCN(c4ccc(Cl)c(Cl)c4)CC3)c(SCc3ccc(F)cc3)nc2=O)cnc1=O +O=C(NCc1cocn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1CCCC2)c1ccc(C(F)(F)F)nc1 +Cc1cccc(S(=O)(=O)NC2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)C2)c1 +CC1CCC2C(C)C(OCCNc3ccc(Nc4ccnc5cc(Cl)ccc45)cc3)OC3OC4(C)CCC1C32OO4 +Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccccc3F)C2=O)cn1 +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CCCC2C(=O)Nc2ccc(C(=O)O)cc2)cc1 +Cn1c(N2CCCN(CCCN3c4ccccc4CCc4ccc(CC(=O)O)cc43)CC2)cc(=O)n(C)c1=O +CC(C)=CCc1c(O)ccc(-c2coc3c(CC=C(C)C)c(O)cc(O)c3c2=O)c1O +COc1ccc(P(=O)(OCC2CCCCC2)N2Cc3ccccc3CC2C(=O)NO)cc1 +CCC(C(=O)NO)N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 +O=c1c(-c2ccccc2)c[nH]c2c(-c3cccc(Br)c3)cnn12 +CCC(OC(Cc1ccccc1)C(=O)N1CCC(OCOC)CC1)C(=O)NC(CC1CCCCC1)C(O)C(O)CC(C)C +CN(C(=O)c1ccccc1)c1ccc2c(c1)nc(NC(=O)c1ccoc1)n2CCC(N)=O +Cc1cccnc1-c1cc(N2CCC(C(=O)NCCc3c[nH]cn3)CC2)ncc1Cl +CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)C2CC=C(C)CC32)CC1(Cl)Cl +CCC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(OC)c1)CC1C(C(=O)O)C1(C)C +CCc1cc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O +O=C1N(CCCCCCCOc2ccc(Br)cc2)CCN1c1ccncc1 +CCn1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCC1)CC2 +O=C(c1cc(COCc2ccccc2)on1)C1CCCN1C(=O)C1CCCN1C(=O)CCCc1ccccc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1NCC1CCNCC1 +O=C(c1ccc(C2=CC3(CCNCC3)Oc3ccccc32)cc1)N1CCOCC1 +O=C(O)Cn1nnc(-c2cnc(N3CCN(c4cc(F)ccc4Cl)CC3)s2)n1 +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCc2ccccc2C1 +Cc1cc(Br)c(Oc2cc(Nc3ccc(C#N)cc3)n[nH]c2=O)c(Br)c1 +CC(=O)C1CCC2C3CCC4CC(O)(C#Cc5ccc(N(C)C)cc5)CCC4(C)C3CCC12C +CC1(C)OC2OC(COS(N)(=O)=O)C3OC(C)(C)OC3C2O1 +CN1C2CCC1C(C(=O)N1CCCC1)C(c1ccc(I)cc1)C2 +COc1ccc(CN2CCN(CC=C(C)C)C(CCCO)C2)cc1 +CN1Cc2cc(-c3ccc(CC(C#N)NC(=O)C45CCC(CC4)CN5)cc3)ccc2C1=O +O=C(CCNC1CCCCC1)NC(c1ccccc1)C1CCCCC1 +Cc1cccc(CNC(=O)c2cc(-c3nnn(CC4CCC(CO)CC4)n3)cc(C)n2)c1 +Cc1cc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)no1 +NC(=O)c1nc(NC2CCNC2=O)nc(-c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)n1 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2NS(=O)(=O)c1cccc(C(F)(F)F)c1 +CN(CC(CCN1CCC(c2cccc(C(F)(F)F)c2)CC1)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 +Cc1nc(-c2cccc(C(=O)NC3CCC(CCN4CCc5ccc(S(C)(=O)=O)cc5CC4)CC3)c2)no1 +COC(=O)CCc1ccc(S(=O)(=O)n2c(C3(O)C=CC(=O)C=C3)cc3ccc(F)cc32)cc1 +CNc1c(-c2ccc(=O)n(-c3ccccc3C)n2)c(-c2ccc(F)cc2)nn1C +c1ccc2c(N3CCC(Oc4nccnc4C4CCOCC4)C3)nccc2c1 +O=C(C=Cc1cccc2ccn(Cc3ccccc3-c3ccccc3)c12)NS(=O)(=O)c1cccs1 +O=C(NO)c1ccc(Cl)c(C(=O)Nc2ccc(Cl)cc2)c1 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(CCCN4CCCC4)cc3)nc12 +COc1cc(CNc2nc(C)cc(NC3CCCCC3)n2)cc(OC)c1OC +COC(=O)c1ccccc1S(=O)(=O)NC(=O)Nc1nc(I)cc(OC)n1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccc(O)cc1 +CC(=O)N1CCN(CCC=Cc2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)CC1 +COc1cc2nc(N3CCN(c4ccc(OC(C)C)nn4)CC3)nc(N)c2cc1OC +CC1CCC(C(C)(NC(=O)c2ccsc2)c2cn(C3(C#N)CC3)nn2)CC1 +CN(CCc1cccc(OC(F)(F)F)c1)CCN1CCCC1 +CC(C)(C)c1cc(C(=O)N2Cc3ccccc3C2)ccc1O +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c(F)cc(N3CCOCC3)cc12 +O=C1c2ccccc2C(=O)N1CCOC(=S)N(C(=O)c1ccc(Cl)c(Cl)c1)c1ccc(Cl)cc1 +COc1cccc(-c2cc(C#N)ccc2C#CC(O)c2cncn2Cc2ccc(C#N)cc2)c1 +Cc1nc(NC(C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc3ncsc3c2)n1 +O=C(C1CC1c1ccc(-c2cn[nH]c2)cc1)N1CCN(C2CCC2)CC1 +O=C1c2cc(COc3ccccn3)nn2CCN1c1ccc(F)cc1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCCN1CCCC1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1-c1cnco1 +Nc1cnc(-n2c(C(Nc3ncnc(N)c3Cl)C3CC3)nc3cccc(Cl)c3c2=O)cn1 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccc(C(=O)O)cc3)cc21 +COc1cccc(Cn2ccc3ccc(-c4ccc5ccn(Cc6cccc(C(=O)O)c6)c5c4)cc32)c1 +CN1CCN(C(=S)NCCCNc2ccnc3cc(Cl)ccc23)CC1 +Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2cccc(F)c2)n1 +CC(C)(C)c1cc(Nc2cc(-c3ccc(OC4CCOCC4)c(C#N)c3)ccn2)on1 +COc1ccc(NC(=O)Nc2nc3nn(C)cc3c3nc(-c4ccco4)nn23)cc1 +Cc1cccc(C)c1NC(=O)Nc1nc2ccccc2n1-c1ccccc1Cl +CCOc1ccccc1-c1ccc(-c2nc3ccc(F)cc3c(NC(Cc3ccccc3)C(=O)O)c2C#N)cc1 +COc1ccc(F)c(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)c1 +CC1NC(=O)c2cc(-c3cccc4c(=O)n(C5CCOCC5)c(NC(C)(C)C)nc34)[nH]c21 +Cc1nc2ccc(F)cc2c(=O)n1-c1ccc(OC2CCN(C3CCC3)CC2)cc1 +COc1cccc(C=NNc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c1 +O=C(NC1CCCCC1)c1cn(Cc2ccccc2)c2ccccc2c1=O +CC#CCCn1ncc2c(N)c(C(=O)NCC3CC3)cnc21 +CS(=O)(=O)c1ccc2c(Sc3ccc(F)cc3)c(CO)[nH]c2c1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(-c5ccccc5)cc4)cc3)cc2n(CCC)c1=O +CCCn1nc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c2cccnc21 +CCN(CCCCCCNC(=O)c1cc(=O)c2c(O)cccc2o1)Cc1ccccc1OC +O=C(CC1CCCCC1)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +N#Cc1ccc(NS(=O)(=O)c2ccccc2C(F)(F)F)cc1 +O=C(O)Cc1cccc2c(OCc3cccc(-c4c(Cc5ccccc5)cnc5c(C(F)(F)F)cccc45)c3)cccc12 +COc1cc(N2CCN(C)CC2)ccc1Nc1nccc(-c2c[nH]c3cnc(C)cc23)n1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1cnc(C(F)(F)F)cc1Cl +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCc1ccc(O)cc1 +COc1ccc(S(=O)(=O)Nc2ncccc2Nc2ccc(O)cc2)cc1 +Cc1ncc([N+](=O)[O-])n1CC(C)OC(=O)C=Cc1cccc2ccccc12 +O=C(Cc1ccc(O)cc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3cccnc3)s2)s1 +CC1CN=C2N(C)C(=O)c3c(nn(Cc4ccc(-c5ccccc5)cc4)c3Nc3ccccc3)N21 +CC1OC(=O)C2CC3CC(NS(C)(=O)=O)CCC3C(C=Cc3ccc(-c4cccc(F)c4)cn3)C12 +O=S(=O)(CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1)C1CC1 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+CCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccccc1 +COC(=O)Nc1nc2ccc(Sc3ccccc3)cc2[nH]1 +CNC(=O)c1cc2c(Oc3ccc(-n4cccn4)cc3)cncc2s1 +CSc1ccc2c(c1)CCN2C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 +CN1C(=O)NC2C3NC(=O)c4ccc(I)n4C3CC21O +CC(c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CCC(CC(C)(C)O)(c2ccc(F)cc2)OC1=O +CCSc1nc(-c2ccccc2)c(-c2ccc(S(C)(=O)=O)cc2)[nH]1 +COc1ccc(-c2csc(C(=O)NCCN3CCOCC3)c2)cc1 +CCCC12CCC(=O)C=C1c1c(cc(OCC(=O)O)c(C)c1C)C2 +CCc1cccc2c3c([nH]c12)C(CC)(CC(=O)O)COC3 +COc1ccc(NC(=O)N2CCC(c3c[nH]c4cccc(F)c34)CC2)cc1N1CCN(C)CC1 +COc1cc(-c2cc(C)c3c(OC)ccc(OC)c3n2)cc2c1OCCN(C(=O)CCn1nc(C)cc1C)C2 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2ccc(C(C)=O)nc12 +C=CC(=O)Nc1ccccc1Nc1nc(NC2CCC(N(C)C)CC2)ncc1Cl +O=C1CC2(CCN(C(=O)NC3CCC(c4cccc(F)c4F)CN(CC(F)(F)F)C3=O)CC2)c2cccnc2N1 +Cc1nc(NC(C)c2cccc(OCC(=O)N3CCOCC3)c2)cc(-c2ccc3ncsc3c2)n1 +Cc1cccc(-c2nc3ccccc3nc2OC2CN(c3ccc4ccccc4n3)C2)c1 +CCSC1=C2CCC3C4CCC(=O)C4(C)CCC3C2(C)CCC1=O +CCC#CCOc1nc(-c2ncccn2)nc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1Oc1ccccc1OC +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)CCC +COc1ccc(-c2cnc3[nH]cc(-c4ccc(OC)c(OC)c4)c3c2)cc1OC +CCCOc1ccc(N2CCC(Oc3ccc(C(C)NC(=O)c4sc(NC(C)=O)nc4C)cc3)C2)nc1 +COc1cc2c(cc1O)C1Cc3sc(CC(C)Cl)cc3CN1CC2 +CCCCN(C=Cc1ncnc2c1ncn2C1OC(CO)C(O)C1O)CCCC +O=C(NCc1ccc(S(=O)(=O)c2ccccc2)cc1)c1cn2ccnc2cn1 +CC1(C)Cc2c(sc(NC(=O)c3cc(C(F)(F)F)n[nH]3)c2C(N)=O)C(C)(C)O1 +COCc1nc2c(C(=O)NCc3ccccc3Cl)cc(NC(=O)c3ccccc3C(F)(F)F)cc2n1C +COc1ccc2c3c1OC1C4(OC)CCC5(CC4COCc4ccccc4)C(C2)N(CC(=O)O)CCC315 +N#Cc1cccc(Nc2nc(-c3ccccc3)nc3ccccc23)c1 +CN(C)CCC(Oc1cccc(NC(=O)Nc2ccc3c(ccn3C)c2)c1)c1ccccc1 +Cc1noc(-c2cccc(-c3cc(F)c(C4(C)CS(=O)(=O)N(C)C(=N)N4)s3)c2)n1 +c1ccc(-c2cc(-c3nn[nH]n3)cnc2-c2ccc(CNCc3ccc(-c4csnn4)cc3)cc2)cc1 +NS(=O)(=O)c1cccc(-c2nc(C(c3ccc(F)cc3)c3ccc(F)cc3)sc2CC(=O)O)c1 +Nc1ncnc2c1c(-c1cccc(O)c1)cn2-c1ccc(OCCNCCO)cc1 +N=C1NC(c2ccccc2)(c2cccc(-c3cccnc3)c2)C(=O)N1C1CCCCC1 +Nc1n[nH]c(N2CCC(N(CCc3ccc(Cl)cc3)Cc3cccc4ccccc34)CC2)n1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NC(=N)N)no2)cc1C#N +COC1C(OC(=O)NC(=O)Cl)CCC2(CO2)C1C1(C)OC1CC=C(C)C +CN(C)CCCc1c(C=C2C(=O)Nc3ccc(S(=O)(=O)N4CCc5ccccc54)cc32)[nH]c2c1C(=O)CCC2 +CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccc3c(c2)OCO3)cc1 +CCN1CCN(c2cc(C)c3cc(NC(=O)C=Cc4cc(OC)ccc4OC)ccc3n2)CC1 +O=C(NCCSC1c2ccccc2COc2ccc(C(=O)O)cc21)OCc1ccccc1 +CCNc1nc2c(c(C(N)=O)n1)CN(C(=O)CCc1ccc(CC(F)(F)F)cc1)CC2 +CC=C1C2C=C(C)CC1(N)c1ccc(=O)[nH]c1C2 +COc1ccc2c(c1)NC1(CCN(C(=O)c3ccc4c(c3)N(C)CCO4)CC1)c1cccn1-2 +COc1cccc(F)c1C1CC(C)C(=O)N1Cc1ccc2oc3ccccc3c2c1 +COc1c(-c2cnn(C)c2)cnc2c1cc(C(=O)NCc1ccc(Cl)cc1)c(=O)n2CC(=O)N1CCC(CO)C1 +CC1(C)SCCCN(S(=O)(=O)c2ccc(Oc3ccccc3)cc2)C1C(=O)NO +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(F)cc4)cc3)c(Br)c2n(CCC)c1=O +CC(C)(C)C(=O)N1CCc2ccc(C(=O)NO)cc2CC1 +CNC(=O)c1ccccc1-c1cnc(Nc2ccc(-c3cnco3)c(OC)c2)o1 +Cc1cccc(-c2noc(C3CN(S(=O)(=O)c4ccc(F)cc4)C3)n2)c1 +N#Cc1cccc(-c2cnc3nnn(CC4CN(c5ncc(-c6cnn(C7CCNCC7)c6)cn5)CCO4)c3n2)c1 +Cc1ccc(Oc2ccc(N(CC(C)(O)C(=O)NO)S(C)(=O)=O)cc2)cc1 +O=C(O)CCc1ccc(C#Cc2ccnc3cc(Cl)ccc23)cc1 +COc1ccc2c(C(=S)N(C)CC(=O)O)cccc2c1C(F)(F)F +CNC(=N)c1cc(C)c2nc(-c3c(NCC(O)c4cccc(Cl)c4)cc[nH]c3=O)[nH]c2c1 +CC1NC(=O)C(C(C)C)NC(=O)CCCCC=Cc2cccc(c2)C(C)OC(=O)C2CCCN(N2)C1=O +CC(=O)Nc1nc2ccc(-c3nn(Cc4cc5cccc(C)c5c(=O)n4C)c4ncnc(N)c34)cc2s1 +CC(=O)N1CCC(c2cccnc2Oc2ccc(Nc3ncccc3F)cc2)CC1 +CCCS(=O)(=O)Nc1cc(Cl)cc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +COc1ccc(F)c(OC)c1C1CC(Cl)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +NC(=O)C(Cc1ccccc1)NC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +Oc1ccnc(-c2ccc(-c3ccc(-c4nc5nc(OC6COC7C(O)COC67)[nH]c5cc4Cl)cc3)cc2)n1 +O=C(NN=Cc1ccc([N+](=O)[O-])o1)c1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +C=C1C(=CC=C2CCCC3(C)C(C(C)CCC(F)(F)C(O)(CC)CC)=CCC23)CC(O)CC1C(F)F +O=S(=O)(c1ccc(C(F)(F)F)nc1)N1C2Cc3[nH]ncc3C1CC(c1ccccc1F)C2 +Brc1ccc2oc(-c3cc[n+](Cc4ccccc4)cc3)cc2c1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3(CO)CC23)c2ncccc12 +COc1ccc(OC)c(N(C)c2nc(Cl)nc3ccccc23)c1 +CC(C)CC(=O)Nc1nc(-c2ccccc2)cc(-c2ccccc2)n1 +Nc1nc2c(ncn2CC(COCCP(=O)(O)O)OCCP(=O)(O)O)c(=O)[nH]1 +COc1ccc(C2(OC(C)C)SC=C(C)n3c2noc3=O)cc1 +O=C(Nc1cccc(C(F)(F)F)c1N1CCOCC1)c1cccc(-c2ccccn2)c1 +CCCCCC=CCC=CCC=CCCCCC(=O)NCCc1c[nH]c2ccc(O)cc12 +CCc1cnc(N2CCC(n3ncc(COc4ccc(-n5cnnn5)cc4)c3C#N)CC2)nc1 +O=C(CN1CCCCC1)N1c2ccccc2Oc2ccccc21 +COc1cccc(-n2ncc3c(NN=Cc4cccc(N)c4)ncnc32)c1 +O=C(NCCN1CCOCC1)c1ccc(F)c(NCc2cnc(Nc3ccccn3)s2)c1 +CCOc1cc(Cl)c(Cc2ncc(-c3ccoc3)s2)cc1C1OC(CO)C(O)C(O)C1O +COc1cccc(NC(=O)Nc2ccc(-c3ncnc4[nH]cc(C)c34)cc2)c1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C(F)(F)F)nn3)c2)c2cnccc21 +CCc1nn(C2CCCC2)c2c1CCN(Cc1ccccc1)C2=O +CCc1nc(N)nc(N)c1-c1ccc(Cl)c(N=NN(CCOC(C)=O)Cc2ccccc2)c1 +CCc1cc(C(=O)Nc2cccc(C(=O)c3ccc4c(C=Cc5ccccn5)n[nH]c4c3)c2)n(C)n1 +CCCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCCC3COC)ccc21 +Cn1cncc1C(c1ccc2c(c1)c(-c1cccc(Cl)c1)nc1nnnn12)n1ccnc1-c1ccc(F)cc1 +O=C(NCCN1CCC(n2c(=O)[nH]c3cc(Cl)ccc32)CC1)c1ccc(F)cc1 +O=C(O)C1CCCN(CCOC=Cc2ccccc2Cc2ccccc2)C1 +Cc1ccc(Cc2ccc3c(c2)C2(OC3)OC(CO)C(O)C(O)C2O)cc1 +CN1Cc2cnc3ccc(-c4cnc5ccccc5c4)nc3c2N(c2ccc(C(C)(C)C#N)cc2)C1=O +Cc1c(-c2ccc3cc(NC(=O)C4CC4)ncc3c2)cnc(CO)c1F +COc1cc(C=C2SC(=O)N(Cc3ccc(F)cc3)C2=O)ccc1OCc1ccc(C(=O)O)cc1 +CNC(=S)OCC1OC(n2cnc3c(NC4CCOC4)nc(Cl)nc32)C(C)(O)C1O +O=C(CCN1CCN(Cc2ccc(Cl)cc2)CC1)N1CCc2ccccc21 +CNCCCN1Cc2ccccc2N(c2ccc(Cl)cc2)S1(=O)=O +CC1OC(OCc2cc(O)c3c(c2)C(C2OCC(O)C(O)C2O)c2cccc(O)c2C3=O)C(O)C(O)C1O +CCc1nc(NCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c2cc(OC)ccc2n1 +Cc1cn(CC(N)C(=O)O)c(=O)n(Cc2ccsc2C(=O)O)c1=O +CCOC(=O)c1c(NC(=O)NS(=O)(=O)c2ccc(C)cn2)sc2c1CCC(C)(C)C2 +CC(C)C(NS(=O)(=O)c1ccc2c(c1)sc1cc(NC(=O)Nc3ccccc3)ccc12)C(=O)O +O=C(Cc1ccccc1)c1ccc(CN2CCC(C(=O)O)C2)cc1 +Cc1cc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)cnc1Oc1ccnc(NC(=O)C2CC2)c1 +Oc1cccc(C23CCN(CCc4ccccc4)C(CC(c4ccccc4)C2)C3)c1 +Cc1cc(OCP(=O)(O)O)cc(C)c1Cc1ccc(O)c(-c2ccccc2)c1 +CCC(=O)Nc1ccc(OCCCNC(C)C)c(Cc2ccccc2)c1 +COc1ccc(C)cc1Nc1nc(N)c2cc(OC)c(OC)cc2n1 +c1ccc(-c2nc(=NCCN3CCOCC3)sn2-c2ccccc2)cc1 +CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccc(-c4cnn(CCN5CCN(CCO)CC5)c4)cc2)CC3)n1 +CC1OC(n2cnc3c(NC4CCCC4)ncnc32)C(O)C1NC(=O)C1(c2ccccc2)CCCC1 +NS(=O)(=O)c1ccc(-c2c(S(=O)(=O)c3ccccc3)no[n+]2[O-])cc1 +Cc1cc(Cl)c(C=CC2CC(O)CC(=O)O2)c(-c2ccc(F)c(C)c2)c1 +Cc1nc(C(C)(CS(C)(=O)=O)NC(=O)c2cc(OCC(F)F)c(C3CC3)cn2)no1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccccc1)CC2 +Cc1c[nH]c(CN2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccnc(F)c4)n3)CC2)n1 +COc1ccc(C)c(Nc2cc(C(F)(F)F)nc(-c3ccncc3)n2)c1 +Cc1cc(=O)n(CC(N)C2CCC(NCc3ccc4c(n3)NC(=O)CO4)CC2)c2cc(F)ccc12 +CN1CCN(CC(=O)C(O)(c2ccccc2)C2CCCCC2)CC1 +CCN(CC)CCn1cc(-c2ccc(F)c(C)c2)nc1C1CCN(c2ncnc(N)c2OC(C)C)CC1 +Clc1ccc(COC(Cn2ccnc2)c2ccc(Cl)cc2Cl)c(Cl)c1 +Cc1cc(C)cc(C(=O)Nc2nccn3c(-c4cccc(NC(=O)Nc5ccc(F)cc5F)c4)cnc23)c1 +CC1CN(Cc2c[nH]nc2-c2c[nH]c(C#N)c2)CCN1c1ccc(C(F)(F)F)cn1 +C#CCN1CCC(COc2nc3scc(C)c3n3cccc23)CC1 +Nc1ncc(CCNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)s1 +COCCOc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCC2)[nH]1 +Cc1cc(NC(=O)C(=O)O)cc(C)c1Oc1ccc(O)c(-c2cccc(F)c2)c1 +COc1ccc(C2(O)CCN(CCCC(C#N)(c3ccccc3)c3ccccc3)CC2)cc1 +Cn1cnc(S(=O)(=O)N(CC2CCNCC2)C2Cc3cc(C#N)ccc3N(Cc3cncn3C)C2)c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCC(O)CC4)cc3OC)ncc2Cl)c1 +COc1cc2nc3c(c(N)c2cc1OC)CCC(CNC(=O)c1cccc(C(F)(F)F)c1)C3 +CN(C)CCCNc1ccc2c3c(nccc13)-c1ccccc1C2=O +CCc1nc(Nc2cc(CCc3cc(OC)cc(OC)c3)[nH]n2)c2ccc(N3CCN(CC)CC3)cc2n1 +CC(C)(C)NC(=O)c1c[nH]c2ncc(Nc3ccc(S(C)(=O)=O)cc3)nc12 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(c2ccncc2)C1 +Cc1ccc2c(c1)N(c1ccc(NCCc3ncc[nH]3)cc1)C(=O)N(C1COc3ccccc3OC1)N=C2C1CCCCC1 +CC(C)(C)c1nc(COc2ccc(C=NNC(=O)c3ccc(O)c(Cl)c3)c3ccccc23)no1 +CN1CCc2cc(Cl)c(O)cc2C2c3cccc(CO)c3CCC21 +COc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(=O)c1cccc(CO[N+](=O)[O-])c1Br)CC2 +O=C(NC1CCN(CC(O)CN(Cc2ccccc2)S(=O)(=O)c2ccccc2)C1)c1cccc2ccccc12 +CN(C(=O)Cc1ccc2ccccc2c1)C1CCCCC1N1CCCC1 +COC(=O)C1(NC(=O)c2ccc(NC(=O)C(=O)c3ccccc3NC(C)=O)cc2)CCCC1 +O=C1NC(=S)N(c2ccccc2)C(=O)C1=Cc1cc(-c2ccccc2)n(-c2ccc(Cl)cc2)c1-c1ccccc1 +Cc1cc(Nc2cc(OCCN3CCOCC3)nc(NCc3cc(-c4ccccc4)no3)n2)[nH]n1 +CS(=O)(=O)c1ccc(-c2nc(NC3CCCC3)cc(C(F)(F)F)n2)cc1 +CC(NS(=O)(=O)c1ccc(Cl)cc1)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1 +COc1cccc(-c2cnc3[nH]cc(-c4ccncc4)c3c2)c1 +COc1cc(C)cc2c1C(C1CCN(C(=O)Cc3cc[n+]([O-])cc3)CC1)c1ncccc1CC2 +O=C1Nc2cccnc2N(C(=O)CC2CCCN3CCCCC23)c2ccccc21 +O=C(NC1CCCN(c2ncnc3[nH]ccc23)C1)C(Nc1ccccc1)C1CC1 +OC(Cc1nc(CC2(C(F)(F)F)CC2)c[nH]1)(c1ccc(-n2cccn2)cc1)C(F)(F)F +O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc2c(c1)nc(O)n2Cc1ccc(F)cc1 +Cc1onc(-c2cccc(Cl)c2)c1COc1ccc(C(=O)N2CCS(=O)(=O)CC2)cn1 +Cc1c(-c2ccccc2F)c(=O)n(CC(N)c2ccccc2)c(=O)n1Cc1ccccc1F +CCNC(=O)c1cc2c(-c3cc(OCCN(C)C)c(Cl)cc3Cl)nc(N)nc2s1 +COCCNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC)ncc1Cl +CCCCN(C(=O)C1=COc2cc(O)c(C(C)(C)C)cc2O1)c1ccccc1 +Cc1c(NC2CC2)nc(C2CCC2)nc1N1CCCCCC1 +COc1cccc(C(=O)Nc2cccc(-c3nc4sccn4c3-c3ccnc(Nc4ccc(N5CCOCC5)cc4)n3)c2)c1 +O=C(NCc1ccccn1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC3CCCC3)n1)CCN2 +Cc1cn(Cn2cnc(-c3cnn(C)c3)c2-c2ccc(C#N)cc2F)nn1 +CC(C)CC(NC(=O)C(C)NC(=O)CC(O)C(COCc1ccc(Br)cc1)NC(=O)c1ccc2c(c1)OCO2)C(N)=O +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5CCCC(C4)N5)cn3)nc2n1C1CCCC1 +COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(C4(CN5CCCC5)CC4)cc2)CC3)cc1 +CC(C)(C)c1cc(C=NNc2nc3ccccc3[nH]2)cc(C(C)(C)C)c1O +Cc1ccc(-c2ccc(C(C)CNS(=O)(=O)C(C)C)cc2)cc1 +O=C(Nc1cn(CC(=O)N2CCC(C(=O)O)CC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +NCCCCCCCCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +CCCOc1cccc2c1cnn2-c1ccnc(NC2CCC(O)CC2)n1 +CC1CN(CC2CCOCC2)CCN1C(=O)N1Cc2c(NC(=O)c3ccc(F)cn3)n[nH]c2C1(C)C +Cn1cc(-c2cnc3ccc4ccc(NS(C)(=O)=O)cc4c(=O)c3c2)cn1 +COc1ccc2c(c1)NC(=O)Cc1c-2[nH]c2ccc(C(F)(F)F)cc12 +O=C(NCc1ccc(Cc2cccc(Cl)c2)s1)C(O)C(O)C(=O)N1CCCC1c1cccc(Cl)c1 +Cc1cccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)c1 +O=C(O)CCC=CCC1COC(c2ccc3cc(C(=CCCCCC(=O)O)c4cccnc4)ccc3c2)OC1c1ccccc1O +Cc1[nH]c(-c2ccccc2Oc2ccccc2)c2cc[nH]c(=O)c12 +CC(Nc1nccc(-n2cnc3ccccc32)n1)c1ccccc1 +COc1ccc2c(c1NS(C)(=O)=O)CCCC2c1c[nH]cn1 +COC(=O)C(c1ccc(Cl)cc1)N1C(=O)c2ccc(C(F)(F)F)cc2NC(=S)C1c1ccc(Cl)cc1 +CCCCn1nc(C2(C)CC2)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ONC(C)(C)C +Cc1ccc(-c2cc(C)c(C(=O)N=C(N)N)cc2S(C)(=O)=O)cc1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)NCC3CC3)cc2F)cn1 +O=C(O)C(Cc1ccc2cc(OCCCN3CCNCC3)ccc2c1)NS(=O)(=O)c1ccc(F)cc1 +CCc1nc(C)n2nc(O)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN1CCC(c2c[nH]c3cnc(NC(=O)c4ccc(F)cc4)nc23)CC1 +COCC(O)COc1ccc(OCc2cccc(Cl)c2)cc1C(C)=O +O=C1c2ccccc2CCC1CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1 +OC1CCN(Cc2ccc(F)cc2)CC1N1CCC2(CCCc3ccccc32)CC1 +COCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCNC(C)=O)C(C)C)ccc1OC +O=C(O)c1ccc2occ(C=NNc3nc4c(c(N5CCOCC5)n3)CSCC4)c(=O)c2c1 +COC1CCC(CC(=O)NC2CCC(CCN3CCC(c4cccc5c4OCO5)CC3)CC2)C1 +NC1Cc2c(ccc3cc(N4CCOCC4)ccc23)OC1c1cc(F)c(F)cc1F +COCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3ccc(F)cc3Cl)cc2[nH]1 +FC(F)(F)c1cccc(N2CCN(CCCN3CC4CCCN4C3)CC2)c1 +Cc1cc(S(=O)(=O)Nc2cc(Cl)c(Oc3cnc4ccccc4c3)c(Cl)c2)ccc1Br +O=C(NN1CCOC1=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1ccccc1 +CC(C(O)c1ccc(O)cc1)N1CCC(O)(c2ccc(Cl)cc2)CC1 +O=C(NCC1CCNCC1)c1cc(F)ccc1-c1cccc(Cl)c1 +Cc1c2c(n3c1CCN(C(=O)C(C)(C)N)CC(C)C(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +CCOC(=O)Nc1cc(-c2ccc(C)cc2NS(C)(=O)=O)nn2c(C)nnc12 +COCCCOc1ccc(-c2nccc(-c3cc4c([nH]3)C3(CCCNC3)CNC4=O)n2)cn1 +COc1ccc(-c2nc(NC(=O)NCCC(=O)NO)cc3c2[nH]c2ccccc23)cc1 +CCCS(=O)(=O)CC(CC)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +C=C1C(CO)C(O)CC1n1cnc2c(=O)[nH]c(N)nc21 +CCC(CS(=O)(=O)C(C)(C)C)N1C(=O)C(C)(CC(N)=O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CC(C)Oc1cc2c(-c3cc(N4C5CCC4COC5)ncn3)n[nH]c2cc1F +O=C(Nc1cccc(-c2ccncc2)c1)C(Cc1ccccc1)NCc1cscn1 +Nc1ccccc1NC(=O)c1ccc(-c2cn(CCc3ccsc3)nn2)cc1 +COCCN1CCC(Nc2cnc3ccc(C#CCNC(=O)c4cccn(Cc5ccc(F)c(F)c5)c4=O)cc3n2)CC1 +CN(C)c1nc(N)nc2[nH]c(-c3ccccc3)c(-c3ccccc3)c12 +Cc1ccc2nc(N)nc(O)c2c1Sc1ccc(C(=O)NC(C(=O)O)c2cccc(C(=O)O)c2)cc1 +COc1ccc(S(=O)(=O)N2CCOCCSC(C)(C)C2C(=O)NO)cc1 +Cc1cnc(-c2cc(Oc3ccc(S(=O)(=O)N(C)C)cc3)cc(OC(C)CO)c2)[nH]c1=O +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3c(OC)cc(OC)cc3OC)CC21C +CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2C3CCCC2CC3)cc1 +CC(C)C(NC(=O)OCc1ccccn1)C(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)NC(=O)OCc1ccoc1 +CSc1nc(NCC2CCCCC2)c(C(=O)O)c(SCc2ccccc2)n1 +Cc1cc(C2CCN(C(=O)C3CN(C(C)(C)C)CC3c3ccc(F)cc3F)CC2)n(-c2ccc(Cl)c(C)c2)n1 +CN1CCC(COCc2cc(C(F)(F)F)ccn2)(c2ccc(F)cc2)CC1 +COc1cc(-c2cnc(C)n2C)ccc1Nc1cc2cc(-c3cnn(C4CCOCC4)c3)ccc2cn1 +CC(C)c1ccc(-c2noc(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)n2)cc1 +CCN(CC)CCOc1ccc2c(c1)C(C)(C)c1sc3ccccc3c1C2=O +NS(=O)(=O)c1ccc2c(c1)CCN2C(=O)C(F)(F)F +CS(=O)(=O)c1ccn2cc(-c3ccc(-c4ccccc4)cc3)nc2c1 +Cc1ccc(-c2nc(NC(=O)CN3CCN(C)CC3)cc(-n3nccc3C)n2)o1 +Nc1nn2cccnc2c1C(=O)Nc1cn(CC(=O)N2CCC(F)(F)C2)nc1-c1cc(Cl)ccc1OC(F)F +COCCN1CCCC(n2nc(C(=O)N3CCOCC3)c3c2-c2cccc(OC)c2S(=O)(=O)C3)C1 +CCCCN1CC=C(c2c(C)[nH]c3ccc(Cl)cc23)CC1 +Cn1c(=O)ccc2cc(NS(=O)(=O)c3cccc(C#N)c3)ccc21 +CC12CCC3C(CC(c4ccc(O)cc4)C4=CC(=O)CCC43C)C1CCC2=O +O=C(CCN1CCCCC1)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +Cn1cc(C(=O)N2CCCC3c4ccccc4CCC32)c2ccccc21 +CCCCOc1ccc(C(=O)Nc2ccc3nc(SCc4c(C)cc(C)c(C(C)=O)c4C)sc3c2)cc1 +Cc1ccc(Cl)c(C(=O)NCC(c2ccc(F)cc2)N2CCOCC2)c1 +CC(=Cc1cccnc1)c1ccc(C(=O)N=c2[nH]c3cc(N(C)C(=O)c4ccccc4)ccc3n2CCC(N)=O)s1 +C=CCNc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n3n2CCC3)n1 +N#CC1(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)CC1 +CN(C)CCNc1cc(-c2ccc(N3CCCCC3)cc2)nc2ccccc12 +Fc1cc(F)c(OC2CCN(c3nc4cnccc4nc3NC3CC3)CC2)c(F)c1 +Cc1cn(-c2ccc(-c3ccc(NC(C)c4ccc(F)cc4)nc3)cc2Cl)cn1 +CCCC1C(=O)Nc2nc(-c3ccc(OCC(=O)NC4CC(C)(C)N([O])C(C)(C)C4)cc3)[nH]c2C1=O +O=C(Nc1c(F)c(F)c(-c2cccc(C(F)(F)F)c2)c(F)c1F)c1nonc1O +OCC1OC(c2ccc(Cl)c(Cc3ccc(OCC4COC4)cc3)c2)C(O)C(O)C1O +O=C(O)CCNC(=O)c1ccc(-c2cc(C(F)(F)F)ccc2CNc2ccc(-c3ccc(Cl)cc3Cl)c(Cl)c2)cn1 +CSc1c(Cl)nc(-c2ccc(NC(=O)Nc3ccc(S(C)(=O)=O)cc3)cc2)nc1N1CCOCC1 +CCCCC(=O)c1c[nH]c2ccc(Cc3ccncc3)cc2c1=O +CC(C)N(c1c(F)c(Oc2cccc(C(=N)N)c2)nc(Oc2ccc(Cc3ccccc3)cc2C(=O)O)c1F)C(C)C +NS(=O)(=O)c1nnc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)s1 +COC1CCC2(CC1)Cc1ccc(-c3cnn(C)c(=O)c3)cc1C21N=C(N)N(C)C1=O +CCCCN(CC)c1ncnc2c1nnn2-c1ccc(C(C)C)cc1Br +CC(C)(C)c1ccc(NCC(O)CON=C(C2CC2)C2CC2)cc1 +O=C(Nc1ccc(CC(N=c2c(O)c(O)c2=NCCCC(F)(F)F)C(=O)O)cc1)c1c(Cl)cncc1Cl +CCS(=O)(=O)N1CCC(N(C)C(=O)NC2CCN(c3cc(F)cc(F)c3)CC2)CC1 +Cc1[nH]c2ccccc2c1CCNC(=O)c1ccc(N(C)C)cc1 +O=C(NCCCC1CCN(CC2COc3ccccc3O2)CC1)Nc1ccccc1 +CC(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccsc3)cc1)C2=O +N#CCCCOc1ccc(-c2ccc(-c3ccccc3)n2CC(=O)NC(=N)N)cc1 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NC2CCCCC2O)cc1 +O=C(NCC1(O)COC1)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +CC(C)n1cnc2c(NCc3ccc(-c4ccccc4)cc3)nc(NC3CCC(N)CC3)nc21 +N=C(N)N1CCCC(NC(=O)CNC(=O)C(CCNC(=O)c2cncc(Br)c2)NS(=O)(=O)Cc2ccccc2)C1O +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3cccc(CN(C)C(=O)C4CCC4)c3)nc2n1 +CCOC(=O)C(=O)Nc1cc(C)nc(N2CCc3ccccc3C2)c1 +FC1(c2cn(-c3ccc(Br)cc3)nn2)CN2CCC1CC2 +Cn1cc(-c2ccc(Cc3n[nH]c4ccc(C(=O)N5CC(O)C5)cc34)cc2)cn1 +C=CCN1CCCC1CNC(=O)c1cc(CCCCl)cc(OC)c1OC +CCN1C(=O)CCCC1C(=O)NCc1ccc(F)c(F)c1F +OCC1NC(C(O)CCCCC2CCCC3(CCCO3)O2)C(O)C1O +NC(CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1)C1CCCCC1 +COc1ccccc1-c1c[nH]c2ncnc(-c3ccccc3)c12 +CCCCCS(=O)(=O)NC(=O)C=Cc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl +COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2cccc(F)c2)CC2CCC1C2 +COc1cc2c3c(c4ccc(OC(C)=O)cc4c2cc1OC)CN1CCCCC1C3 +COc1cccc(-c2cnn(CC3CCc4c(cccc4OCC(=O)O)C3)c(=O)c2-c2ccccc2)c1 +O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2ncccn2)CC1 +N#CC1CCCN1C(=O)CNC(=O)c1cccc2ccccc12 +CCCCCCCCCCCCCC1=C(O)C(=O)C=C(OC)C1=O +O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCCOc3ccccc3)ccc1-2 +CN1CCc2nc(NC(=O)c3cccc(CNC(=O)c4ccc(-n5ccnc5)cc4)c3)sc2C1 +O=C(Nc1ccc(-c2nc(C3=CCOCC3)c3sccc3n2)cc1)Nc1cccnc1 +CCCc1ccc(C=C2CN3C4CCC3C(C(=O)OC)C2C4)s1 +Cc1nc2nc(C(=O)N(C)CCc3ccccn3)cn2c(-c2ccc(Cl)cc2Cl)c1CN +CCOC(=O)C1CCN(C(=O)CCc2ccc(-c3ccc(CCN4CCCC4C)cc3)cc2)CC1 +CNC1CCN(C(=O)C2CCCCN2S(=O)(=O)c2ccc(-c3ccc(C)o3)cc2)C1 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+O=C(C(Nc1ccccc1F)c1cc2ccccc2s1)N1CCCC1c1ccccc1F +CN(CCOc1ccccc1C(C)(C)C)C(=O)Nc1ccccc1C(=O)O +NC1(c2ccc(-c3nn4c(-c5ccn[nH]5)cnc4cc3-c3ccccc3)cc2)CCC1 +CN(C(=O)C(Cc1ccc(CN)cc1)NS(=O)(=O)c1ccc(-c2ccccn2)s1)C1CCCC1 +COC(=O)C(Cc1ccc(OCCOc2ccc3ccccc3c2)cc1)C(=O)OC +COc1ccccc1C(Cn1c(=O)n(C(C)(C)C(=O)O)c(=O)c2c(C)c(-c3ncco3)sc21)OC1CCOCC1 +COc1ccc(S(=O)(=O)N(Cc2ccc3c(n2)C=CC(C)(C)O3)C2CCCCCCC2)cc1OC +CC#CC(C)(C)Oc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(S(=O)(=O)C(C)C)CC2)cc1 +COc1ccc(-c2cc(CNc3ccc(S(=O)(=O)Nc4nnc(C)s4)cc3)cc(C(=O)NC(CO)CO)c2)cn1 +CS(=O)(=O)N1CC=C(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +N#Cc1ncc(C(=O)NCC(F)(F)F)c(N2CCC(S(=O)(=O)c3cccc(Cl)c3Cl)C2)n1 +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3C4CCC(C4)C3N(Cc3cccs3)C1=O)N2 +CC(C)(C)OC(=O)N1CC2CC1C1(C)C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)N21 +O=C(O)CCc1ccc(-c2c(C=Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cn1 +Cc1cc(Nc2cc(C(F)F)ccn2)nc(-c2ccc(C(C)(O)C3CCC(C(=O)O)C(C)C3)nc2)c1 +Cc1cccc(COc2ccc(S(=O)(=O)C3CCOCC3(O)C(=O)NO)cc2)c1 +COC(=O)c1ccc(Oc2ccc(C=C3SC(=O)NC3=O)cc2OC)cc1C(F)(F)F +CC(C)Oc1cccc(-c2cnnc(-c3ccccc3)c2)c1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCN(C(=O)C2CCCCC2)CC1 +CCC1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 +COc1ccc2c(c1)[nH]c1c3[nH]c4cc(Br)ccc4c3c3c(c21)C(=O)NC3=O +CCCCOc1ccc(S(=O)(=O)N2CC(NC(=O)C(O)CC(C)C)CC2C(=O)NO)cc1 +CCCC(CCC)C(=O)Nc1ccc(S(N)(=O)=O)cc1Br +COc1cc2nncc(-c3cnc(N4CCC(C(C)(C)O)CC4)c(C(F)F)c3)c2cc1OC +CC1CCCCN1CCCNC(=O)c1ccc2nc(N3CCCCC3)sc2c1 +CCn1nccc1-n1nnc2c1CC(C)N(C(=O)c1cccc(C(F)(F)F)c1Cl)C2 +CN1CCN(c2cccc(Nc3nc4c(NCc5ccccc5CN(C)S(C)(=O)=O)cccn4n3)c2)CC1 +CC12CCC3C(CCC4=CC(O)CCC43C=NO)C1(O)CCC2C1=CC(=O)OC1 +Cn1cc(-c2cc(C(N)=O)nc3cc(CN4CCOC(CC(F)(F)F)C4)ccc23)cn1 +CN1Cc2cc(C(F)(F)F)ccc2Oc2ccc(-c3cccc(C(O)CO)n3)cc21 +c1ccc2oc(CN(CCCCCCCNc3c4c(nc5ccccc35)CCCCC4)Cc3cc4ccccc4o3)cc2c1 +Cc1nn(C2CCN(CC(=O)N(C)C)CC2)c(C)c1Nc1ncc(Cl)c(-c2cnn3ccccc23)n1 +COc1cccc(NC(=O)C=Cc2ccc(C(C)(C)C)cc2)c1 +CN1CCN(c2nccn3c(-c4ccnc(NC(CN)c5cccc(Cl)c5)n4)cnc23)CC1 +O=C(c1cccc(Cc2n[nH]c(=O)c3ccccc23)c1)N1CCN(c2ccccn2)CC1 +COc1cccc2c1C(C(=O)NCc1ccc(OC(F)(F)F)cc1)N(CCc1ccccn1)C2=O +CCCSc1nc(Sc2ccccn2)c2nnn(Cc3ccccc3)c2n1 +Cc1c(Sc2ccc(Cl)cc2)c2c(S(C)(=O)=O)cccc2n1CC(=O)O +N#Cc1cncc(N2CCC(S(=O)(=O)c3ccc(N4CCN5CCCC5C4)cc3Cl)C2)n1 +Cc1ccc(NC(=O)c2cncc(N(C)C)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)n1 +CC(C)N1CCC(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)CC1 +Cc1nsc(-c2ccc(N3CCN(c4cccc(Cl)c4)CC3)nn2)n1 +COc1cc2oc(=O)c(OCCCCOc3cc(O)cc(N(C)C)c3)c(C)c2cc1OC +Cc1sc(-c2ccccc2)nc1CCNC(=O)c1c(C(=O)N2CCC2)cnn1C +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)NCc3ccccn3)[nH]c12 +NCCCOc1cc(C(N)=O)c2ncnc(NCc3ccc(C(F)(F)F)cc3)c2c1 +Cc1ccc(C(=O)NC2CC2)cc1Nc1ncnn2cc(C(=O)c3ccc[nH]3)c(C)c12 +COc1ccc(C(=O)Nc2ccc(C)c(-n3cc(-c4cccnc4)cn3)c2)cc1 +O=C(NC1CCN(CCc2ccc(OC3CCNCC3)c([N+](=O)[O-])c2)C1)c1ccc(Cl)c(Cl)c1 +Cc1c(-c2cccc(OCC(=O)O)c2F)c(=O)n(CC(N)c2ccccc2)c(=O)n1Cc1c(F)cccc1C(F)(F)F +CCN(CC(O)(CNc1cccc2c1cnn2-c1ccc(F)cc1)C(F)(F)F)C(=O)c1ccccc1C 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+COc1cc(F)c(-c2nc3c(NCC4CCNCC4)c(Cl)cnc3[nH]2)cc1OC +CC(c1ccc(OC(F)(F)F)cc1)N1CCC2(CCC(O)CC2)OC1=O +Nc1ccc(CC(C(=O)O)c2cn(Cc3ccccc3)cn2)cn1 +CC(C)Nc1cc(-n2ccc3cnc(N4CCC(O)C4)nc32)ncc1C(=O)NCC(F)C(C)(C)O +CC(C)CCN1C(C)CCCC1C(=O)NC(Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)OC(C)(C)C +CC(C)NC(=O)c1cccc(-c2cc(-c3ccc(CNC4CCOCC4)cc3)on2)c1 +CC(C)n1nnc(-c2onc(O)c2CC(N)C(=O)O)n1 +CCNCc1cccc(C(=O)Nc2cc(C)n(Cc3cc(Cl)ccc3OCC(C)C)n2)c1 +O=C(Nc1ccc(C2CNCCO2)cc1)Nc1ccccc1Cl +COc1cccc(-c2nc(N)c3c(C)c(C)n(C(C)c4ccccc4)c3n2)c1 +CN1CCCC1COc1cnc(Cl)c(C=Cc2ccccn2)c1 +O=C(CCC(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCC(CO)(Cc5ccccc5F)C4)cc23)ccn1 +COc1ccc(Cn2c(N(C)C)nc3cc(-n4cnc5cc(-c6ccc(Cl)cc6)sc5c4=O)ccc32)cc1 +Oc1cc(Nc2cccnc2)cc(-c2cccc3[nH]cc(Cl)c23)c1 +NC(=O)C1CCCN(c2nc(N3C4CCC3COC4)nc3scc(-c4ccccc4Cl)c23)C1 +O=C(COc1ccccc1C1CCCCC1)NCC(O)CN1CCc2ccccc2C1 +COc1ccc(C=C2SC(=Nc3cccc(C(=O)O)c3)N(C)C2=O)cc1 +CCc1sc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)nc1CN(CC)CCO 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+COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccc3o2)CC1 +Cn1cnc2cc(-c3ccc(N4CCC(CO)C4)c(S(C)(=O)=O)c3)nc(NC3CC3)c2c1=O +COCCn1c(-c2ccc(Cl)s2)nn(CC(=O)NCC(NC(=O)OC(C)(C)C)c2ccccc2C(F)(F)F)c1=O +CS(=O)(=O)N(CC(C(=O)NO)N1CCN(c2ccc(Cl)cc2)CC1)c1ccc(Oc2ccc(C(F)(F)F)cc2)cc1 +CC(C)C12OC1C1OC13C1(OC1C(O)C1(O)C4=C(CCC13C)C(=O)OC4)C2O +COC(=O)c1ccc(-c2ccc3c(c2)Nc2ccccc2NC3=O)cc1OC +CC(=O)SCCC(=O)N1C(C(=O)O)CC2CCCCC21 +COc1cccc2c1CCN2Cc1cnc2nc(N)nc(N)c2c1C +CCOc1nc2c(C(=O)NCc3ccccc3C(F)(F)F)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CC1Cc2ccccc2N1C(=O)CN1CCN(Cc2ccccc2Cl)CC1 +CN1CCN(c2ccc3[nH]c(-c4ccc5[nH]c(CCCCCCc6ccc(N(CCCl)CCCl)cc6)nc5c4)nc3c2)CC1 +NC(=O)c1c(N2CCN(CCO)CC2)nc2sc3ccccc3n2c1=O +N#Cc1cnc2c(Cl)cc(NCc3cn(Cc4ccccn4)nn3)cc2c1Nc1ccc(F)c(Cl)c1 +CCCOc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2noc(O)n2)cc1 +OC1(c2cccnc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +Cc1cnc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)s1 +O=C(NCCN1CCNCC1=O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CCOC(=O)c1nn(C(=O)c2ccsc2)c2ccccc12 +CC1CN(C(=O)c2ccc(-c3ccncc3)c(F)c2)CCN1C(=O)c1ccc2cc[nH]c2c1 +COc1ccc(Nc2cc(NC3CCCCC3N)nnc2C(N)=O)nc1OC +Cc1cc(Sc2ccccc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +CSc1cccc(NC(=O)CN2CCC(c3cccc[n+]3[O-])CC2)c1 +CC(NC(=O)C(C)(C)C)C(Oc1ccc2c(cnn2-c2ccc(F)cc2)c1)c1ccccc1 +O=C(NCC1(N2CCOCC2)CCCCC1)c1ccc2[nH]nc(-c3ccc(N4C5CCC4COC5)cc3)c2c1 +Cc1nnsc1C1=NNC(=O)C1=Cc1cn(C)c2cccc(OCc3ccccc3F)c12 +CC(C(=O)NCc1cc(C(F)(F)F)nn1-c1cccc(Cl)c1)c1ccc(C(=O)Nc2ccc(F)cc2)cc1 +S=C(SSC(=S)N1CCOC(COc2ccccc2)C1)N1CCOC(COc2ccccc2)C1 +Nc1ncc(C2CCC(O)CC2)nc1-c1ccc(C(=O)NCc2ccccc2)c(F)c1 +O=c1n(CCc2ccc3ccccc3n2)nc2cccc(N3CCCCC3)n12 +O=C1c2cc(-c3ccnc(NC4CCOCC4)n3)[nH]c2CCN1C(CO)c1ccccc1 +N=C(Nc1ccc(CNCCc2cccc(NC(=N)c3cccs3)c2)cc1)c1cccs1 +COc1cc(NC(=Nc2ccccc2)NC#N)ccc1-c1cnco1 +CCS(=O)(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C(=O)NC +CC(=O)c1c(O)c(C)c(O)c2c1OC1=CC(=O)C(=C(C)Nc3ccc(Br)cc3)C(=O)C12C +CNC(=O)C1Cc2cc(F)ccc2N1C(=O)COc1ccc(F)cc1 +Nc1ccn2c(-c3ccncc3)c(-c3ccc(F)cc3)nc2n1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3C)C2)cc1 +CN(C(=O)C1CCc2cc(NS(C)(=O)=O)ccc2O1)C(CN1CCC(O)C1)c1ccccc1 +COc1ccc(-c2ccc(OCc3cc(C(=O)NS(=O)(=O)c4ccccc4)oc3C)cc2)nc1 +O=C(NC1CCN(CCc2ccc(OC3CCNCC3)cc2)C1)c1ccc(Cl)c(Cl)c1 +CCC(C)(C)Nc1cccnc1N(C)C1CCN(C(=O)c2cc3cc(NS(C)(=O)=O)ccc3[nH]2)CC1 +O=C1OC2(CCN(Cc3ccccc3)CC2)c2c(-c3cccc4ccccc34)sc(-c3cccc4ccccc34)c21 +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)c1ccccc1-c1cncnc1 +CCN(C(=O)c1ccc2[nH]c(-c3cc(C)cc(C)c3)c(CCNCCCCc3cccnc3)c2c1)C(C)C +Cc1sc(-c2ccc(C(C)C)cc2)nc1CCOc1ccc2c(c1)CCC2CC(=O)O +CC(C)OC(=O)C(C)NP(=O)(COC(C)Cn1cnc2c(N)ncnc21)Oc1ccccc1 +Nc1ncc2c(n1)-c1c([nH]c3ccc(Cl)cc13)CCC2 +COc1cc(C(=O)NCc2cccc(Cl)c2)ccc1-c1cn[nH]c1 +NC(=O)NC1=C(C(N)=O)C=C(c2ccc(F)cc2)C1 +CN(C)c1cccc2c1CCN(C(=O)C=Cc1cc(Cl)ccc1-n1cnnn1)C2C(=O)Nc1ccc(C(=O)O)cc1 +CCCCCCCNC(=O)C1(C)CC(c2ccc(C)cc2)=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1 +COc1cc(C(=O)Nc2ccc(-c3cccc([N+](=O)[O-])c3)cc2)cc(OC)c1OC +C#Cc1nc(NOC)c2ncn(C3OC(CO)C(O)C3O)c2n1 +O=C(Nc1ccc(N=C2NCCN2)cc1)c1ccc(N=C2NCCN2)cc1F +Cc1c(CC(=O)Nc2ccncc2)c2cc(F)ccc2n1Cc1ccc(F)cc1 +CCN=C1SC(=Cc2cc(C)n(-c3ccc(F)cc3F)c2C)C(=O)N1CC +Cc1cccc(CCNCc2cc3cc(C)cc(C)c3nc2O)c1 +N=C(N)c1ccc2cc(OC(=O)c3ccc(NC4=NCCN4)cc3)ccc2c1 +O=C(c1ccc(N2CCCC2)c(OCC2CC2)n1)N1CC2(COC2)C1 +COc1cccnc1C(C)c1c(CCN(C)C)sc2ccccc12 +CN(C(=O)Cc1cccc2occc12)C1CCCCC1N1CCCCCC1 +NC(=O)Nc1sc(-c2ccc(Cl)cc2)cc1C(=O)NC1CCCNC1 +CS(=O)(=O)c1ccc(-n2cc(C(F)F)nc2-c2ccc(Cl)cc2)cc1 +COc1ccc(N2CCN(CCCC(=O)NC3c4ccccc4C=Cc4ccccc43)CC2)cc1OC +COc1nccc2c1ccc1nc3cccc(C(=O)NC(CO)CN(C)C)c3nc12 +CN(C)C(=O)CN1CCC(CCOc2ccc(-c3cc4c(ncn4C)c(C#N)n3)cc2C(F)(F)F)CC1 +CC(=O)c1cc(Cl)c(C(=O)Nc2ccnc(NC(=O)C3CC3)c2)c(Cl)c1 +CC(C)CC(NC(CCc1ccccc1)C(=O)O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +COc1ccc2[nH]cc(CN3CCCC4(CCN(c5nc(C)cc(C)n5)CC4)C3=O)c2c1 +CCCCNc1ncc(C(=O)NCc2ccc(F)cc2)c(NC2CCC(O)CC2)n1 +CCOC(O)=C1C(COCc2cc(O)nc(C(C)(C)C)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +O=C1c2ccc(Nc3ccc(F)cc3F)cc2CCc2ccc(O)cc21 +CCCCC(NC(=O)OC(C(C)(C)C)C(C)(C)C)C(=O)C(=O)NC(C)c1ccccc1 +CCN(CC)CC#CCN(c1c(C)cc(Br)cc1C(=O)NO)S(=O)(=O)c1ccc(OC)cc1 +O=C(c1cccnc1)N1CCC(n2ncc3c(N4CCOCC4)nc(-c4ccc5[nH]ccc5c4)nc32)CC1 +O=C(NCCCNCc1ccc2ccccc2c1)c1ccc2nc(NC(=O)C3CCCCC3)sc2c1 +CN(CC(C)(C)O)C(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +COc1ccc(NCc2cnc3nc(N)nc(N)c3c2C)c2ccccc12 +CCc1nccc(-c2ccc(C(=O)N3CCN(CC)CC3)c(F)c2)c1C#Cc1ccc(N)nc1C +CCN(CCNC(=O)c1ccccc1)C(=O)c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +CCCc1nc(C)n2c(O)nnc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCN(CC)C(=O)C1(c2ccccc2)CC1CNCC(O)COc1cccc2[nH]ccc12 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cccc(OCc4ccccc4)c23)C1(C)C +O=C(C=Cc1ccc(Sc2ccc(Cl)cc2Cl)c(Cl)c1)N(CCO)CCO +Cc1[se]c(C=C2C(=O)Nc3cc(-c4cccc(O)c4)ccc32)cc1C(=O)NCCCn1ccnc1 +CCOc1cc2cc(-c3c(C)nc(NCCOC)nc3NC3CC(CO)C(O)C3O)oc2c(C)n1 +NC(=O)c1cc(OCCO)cc2c1-c1ccccc1C2(O)C(F)(F)F +CCCCCCCCCCCCCC(=O)CC(=O)Nc1c(C(C)C)cccc1C(C)C +CCC(CN(C)S(=O)(=O)C1CC1)N1C(=O)C(C)(CC(=O)O)CC(c2cncc(Cl)c2)C1c1ccc(Cl)cc1 +C#CC(=O)Nc1cc(-c2cnc3[nH]cc(Cl)c3c2)ccc1F +O=C(O)CC(NC(=O)CCCCc1ccc2c(n1)NCCC2)c1cnc2ccccc2c1 +CSc1nc(-c2cccc(C(F)(F)F)c2)c(-c2ccnc(NC(C)c3ccccc3)c2)[nH]1 +c1cc2c3cnc(Nc4ccc(N5CCNCC5)nn4)nc3n(C3CCOC3)c2cn1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(N3CCN4CCCC4C3)nc12 +COc1ccc(C(=O)Nc2cnccc2Cl)cc1OC1CCCC1 +O=C(Nc1ccon1)c1cc(-c2cccnc2)nc2ccc(Cl)cc12 +O=C1C(NS(=O)(=O)C=Cc2ccc(Cl)s2)CCN1c1ccc(C2CCCN2)cc1F +COc1cc(Nc2c(C#N)cnc3cc(-c4ccsc4CN4CCOCC4)ccc23)c(Cl)cc1Cl +NS(=O)(=O)c1ccc(C(=O)CSc2ncccn2)cc1Cl +Cc1nc(NC(C)c2cccc(-c3ccc(CO)nc3)c2)cc(-c2ccc3ncsc3c2)n1 +O=S(=O)(Nc1ncns1)c1ccc(Oc2cc(C(F)(F)F)nn2-c2ccccc2)c(F)c1 +CCCSc1nc(N2CCCC(Cc3nnn[nH]3)C2)ccc1C(=O)NC1CCCCC1 +Cc1cc(C)n(-c2ccc(C(=O)N3CCC(F)(F)C(=CC(=O)NCc4ccccn4)c4ccccc43)c(Cl)c2)n1 +COC(=O)N1CCC(Oc2ncnc3c2CN(c2cnc(OC)c(C#N)c2)CC3)C1 +O=C(Nc1ccc(OC2CCN(C(=O)C3CCCCO3)C2)cc1)N1Cc2ccncc2C1 +CC(C)C1CN(C(=O)Nc2cccc(F)c2)CCN1C(=NC#N)Nc1cccc2[nH]ncc12 +CCCN(CCC)c1cc(C)nc2c(-c3ncc(O)cc3C)c(C)nn12 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+CN(C)CC1Cn2c(-c3cccc(Cl)c3)c3c(=O)n(C)c(=O)n(C)c3c2C(c2ccc(Cl)o2)O1 +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccncc1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(CCCCCl)Oc1ccccc1-3 +O=C1CCOc2c(OCCNCCCCc3ccc4c(c3)CCO4)cc(F)cc21 +CC(O)(c1ccc(C(=O)N(C2CC2)C2CCC(C#N)(C3CC3)CC2)cc1)C(F)(F)F +CNC(=O)c1ccc(-c2cnc3nnc(Cc4ccc5ncccc5c4)n3n2)cc1F +COc1ccc2c(C=C(C)C(=O)c3cc(OC)c(OC)c(OC)c3)cn(CCO)c2c1 +O=C(O)COc1ccc(Cl)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1Cl +CCOCCC1(Oc2ccc(Oc3ccc(C(=O)NCc4cccc(F)c4)cc3)cc2)C(=O)NC(=O)NC1=O +CCCCC(NC(=O)OCC1(CSc2nccn2-c2ccccc2)CCC1)C(=O)C(=O)NC(C)c1ccccc1 +CC(C)C(C)Nc1cc(-c2[nH]c([S+](C)[O-])nc2-c2ccc(F)cc2)ccn1 +Nc1nc(N)c2cc(C=CC(=O)Oc3ccccc3)ccc2n1 +COC(=O)c1c(C(=O)N2CCC(=O)CC2)cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(Nc3ccc4ccn(C)c4c3)CC2)CC1 +O=C(NO)c1cnc(NC2(c3ccc(F)cc3Cl)CC2)nc1 +O=C(Nc1ccc(C2CCNC2)cc1)OCCc1ccc(Cl)cc1 +Clc1cccc(Cl)c1-c1nc2ccnc(Nc3cc(N4CCOCC4)ncn3)c2[nH]1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(c2cccc(C#N)n2)CC1 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+Cc1cnc(N2CCN(C(=O)C3CCS(=O)(=O)CC3)C(c3ccc(F)cc3)C2)nc1 +CC1(O)C(O)C(COC(=S)NCc2ccccc2)OC1n1cnc2c(NC3CCCC3)ncnc21 +O=c1[nH]c(Oc2cnn(Cc3ccccc3)c2)nc2cnccc12 +O=C(Nc1ccccc1)Nc1nc2ccccc2n2c(=O)c(-c3ccccc3)nn12 +CCC(=O)N(c1ccccc1)C1(COC(C)=O)CCN(CCc2cccs2)CC1 +Nc1ncc2ccc(-c3ccc(NC(=S)Nc4ccc(F)c(F)c4)cc3)cc2n1 +CC(=O)c1ncnc2c(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12 +CCC(O)=C(C#N)C(=O)Nc1ccc(-c2ccc3c(c2)OCCO3)c(C(=O)OC)c1 +COc1cc2c(cc1C(=O)Nc1ccc(O)cc1)CCC1C2(C)CCC(O)C1(C)C +CCCCn1c(Sc2nc3cccc(OC)c3s2)nc2c(N)ncnc21 +CCN(CC)C1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4ccc(O)c(OC)c4)cc23)CC1 +CCc1cccc2c(-c3nsc(CN4CCCC4)n3)cn(CC3CCOCC3)c12 +Cc1cc(NCCNC2CCCC2)n2nc(C)c(-c3c(Cl)cccc3Cl)c2n1 +Cc1cnc(-c2cc(N3CCC(NC(=O)CN(C)C)CC3)ncc2Cl)c(C)c1 +CCC(c1nn2cccc2c(=O)n1Cc1ccccc1)N(CCC(C)(C)N)C(=O)c1ccc(Cl)cc1 +C#Cc1cccc2oc(C(=O)Nc3ccc(-c4ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc4)cc3)c(C)c12 +CN1CCN(C(=O)C(Cc2ccncc2)c2ccccc2)CC1 +O=C(c1cccc(-c2cccc(O)c2F)n1)c1ccc(O)c(O)c1O +Cc1cc(COC2C(O)C3C(C(=O)O)C3C2(N)C(=O)O)ccc1F 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+O=C1c2cc(-c3ccnc(NC4CCC(O)C4)n3)cn2CCCN1C(CO)c1ccccc1 +CCc1nc2cc(F)ccc2n1-c1ccc(C(=O)NC2CC2)s1 +CC(=O)Nc1cccc(C2CCN(CCCNc3nc4ccccc4n3Cc3ccc(C(C)(C)C)cc3)CC2)c1 +Cc1nc(O)c2cc(NCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cn3)ccc2n1 +CC(C)CN(Cc1ccc(NC2(C)CCN(S(C)(=O)=O)CC2)cc1)S(=O)(=O)Cc1ccccc1 +CC(C)CC(NC(=O)Cc1ccc(F)cc1)c1nc(C(=O)NC(CCCNC(=N)N)C(=O)O)co1 +O=C(NCC(c1cnc(C(F)(F)F)nc1)N1CCC(F)CC1)c1ccccc1Cl +CCCOC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1 +CC(C)(C)NC(=O)Nc1nc2nc(N)ncc2cc1-c1c(Cl)cccc1Br +COc1cc(C(=O)NC2CCN(C)CC2OC)c(F)cc1Nc1ncc(Cl)c(Oc2cccc3c2C(=O)N(OC)C3)n1 +Cc1csc2nc(C(C)NC(=O)C=Cc3ccc(N(C)C)cc3)oc(=O)c12 +NS(=O)(=O)c1nc2ccc(ONC(=O)c3cccc(C(=O)O)n3)cc2s1 +CN1C(=O)C(c2ccc(OC(F)F)cc2)(c2ccc(F)c(OCCF)c2)N=C1N +O=C(CCCCc1cccn1Cc1cccc(-c2ccccc2)c1)NO +CC1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4)cc32)C(CN2CC(C)OC(C)C2)CN1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(C(F)(F)F)c(F)c4)cn3CCN3CCC3)CC2)c1C1CCC1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(Cl)nccc2n1CC(=O)O 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+O=C(c1cccc(OCC(O)CNC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)c1)N1CCOCC1 +COc1cc(Cl)c(C)cc1NS(=O)(=O)c1ccc(OC)c(N2CCNCC2)c1 +COc1ccc2sc3c(c2c1)N(Cc1ccccc1Cl)CCNC3=O +COCc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +COC(=O)C(CCSSCCC(NCCC(=O)c1cc2ccccc2s1)C(=O)OC)NCCC(=O)c1cc2ccccc2s1 +CC1CCN(C(=O)C2CCN(Cc3ccccc3)C2=O)CC1N(C)c1ncnc2[nH]ccc12 +CNC(=O)C(C)n1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5ccc(C)cc5)cc4)csc23)cn1 +COc1cc(CNC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cc(OC)c1 +NS(=O)(=O)c1ccc(SCc2ccc(C(F)(F)F)cc2)s1 +CCOC(=O)c1cc(C#N)c(N2CCC(C(=O)NS(=O)(=O)c3ccccc3)CC2)nc1C +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(CO)(Cc5c(F)cccc5F)C4)cc23)ccn1 +Cc1nn(C)c2nnc(Nc3ccc(S(=O)(=O)N4CCCCC4)cc3)nc12 +CC(=O)Nc1cccc(-c2c(-c3ccc4nccnc4c3)n(C)n(C)c2=O)c1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(CCO)cc3)cc2s1)S(=O)(=O)CCC(F)(F)F +COc1cccc(S(=O)(=O)Nc2ccc(NS(=O)(=O)c3cccc(OC)c3)c3ccccc23)c1 +Cc1cc(C)c2sc(N(CCCN(C)C)C(=O)c3ccc(S(=O)(=O)N(C)C4CCCCC4)cc3)nc2c1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(S(C)(=O)=O)cc3)CC2)ncc1Br +Fc1ccc(COc2cn3c(-c4ccc(OC(F)F)cc4)nnc3cn2)cc1F +Cc1cccc2cc(C(=O)NCCCCCC(=O)Nc3ccccc3N)[nH]c12 +CCc1cn(C2CC(O)C(CNC(=O)Cc3c(C)cccc3C)O2)c(=O)[nH]c1=O +CC(C)(C)NC(=O)C1CCN(Cc2nccc(NC(=O)c3cccc(C(F)(F)F)n3)n2)CC1 +COc1ccc(-c2nc(Nc3cccc(NC(=O)C4CCNCC4)c3)nc3[nH]cnc23)cc1OC +CC(c1ccc(-c2cccc(S(N)(=O)=O)c2)cc1)C(N)C(=O)N1CCC(F)C1 +CS(=O)(=O)Cn1cnc2c(N3C4CCC3COC4)nc(-c3cnc(N)nc3)cc21 +FC(F)(F)c1ccc2[nH]c(N3CCN(c4ncccc4C(F)(F)F)CC3)nc2c1 +[O-][S+](c1ccc(C(F)(F)F)cc1)c1c(O)c(-c2cccnc2)cc2ccccc12 +COCCCCC(O)(c1ccc(F)cc1-c1cccc(C)c1)C1CCCN(C(=O)C2CC(N)C(O)C2)C1 +O=C(O)c1cc2c(s1)-c1cc(F)c(Cl)cc1OC2 +COc1cc2c(=O)n(CCN3CC4CCc5c(OC)cccc5C4C3)c(=O)n(C)c2cc1OC +O=C(C=Cc1ccc2c(c1)CN(S(=O)(=O)c1ccccc1)C2)NO +COCCNc1cc(NC(=O)N2CCCc3cc(-c4cn(C)nc4C)c(C=O)nc32)ncc1C#N +CCOC(=O)CCCn1c(=O)oc2cc3ncnc(Nc4ccc(OCc5ccc(Cl)cc5)c(Cl)c4)c3cc21 +COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N2CCC(CN3CCN(C)CC3)CC2)c(C)c1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccccc1OCc1cccs1 +Cc1cc(-c2cnc3c(NCCC(F)(F)F)cc(C(F)(F)c4cccc(F)c4)nn23)ccc1C(=O)NC1CC1 +Cc1cc(C(=O)N(C)C)cc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Br)c(C)c3)CC2)n1 +CC(CCc1ccccc1)NCC(O)c1cc(C(N)=O)c2[nH]ccc2c1 +Cc1ccc(Oc2ccc(C(=O)NCCN3CCCC3)cc2NC(=O)C2CC2c2ccccc2)cc1C +COc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCCCC4)cc3)cc12 +OC1(c2ccc(Cl)cc2)CC2CCC(C1)N2CCCSc1ccc(F)cc1 +N#Cc1ccc(Cn2cncc2CNC2CCN(C(=O)c3cccc4ccccc34)C2=O)cc1 +Cc1ccc(OCC(C)(C)O)cc1-c1nnc2c(C)nc3ccc(C(C)C)nc3n12 +O=C(Cc1cccc(Cl)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)(F)F)c3)s2)nn1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2c(-c3ccncc3)cccc21 +C=Cc1ccc(CN(C(Cc2cccs2)C(=O)NO)S(=O)(=O)c2ccc(OC)cc2)cc1 +CCCn1c(-c2ccccc2)cc(C(=O)NCCCN2CCN(c3cccc4cccnc34)CC2)c1C +COCCNC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2ccccc2)cc1 +O=C(NC=Cc1ccccc1)C(c1csc2ccc(Cl)cc12)P(=O)(O)O +COc1cc(-c2nnc3n2CCCC32C(=O)N(CC(F)(F)F)c3ccccc32)ccc1-c1cnc(C)o1 +CC(C)(NC(=O)c1ccc(C2CC2)c(OCC(F)(F)F)n1)c1nccs1 +CCN(c1cc(Cl)cc(C(=O)NCc2c(C)cc(C)n(C)c2=O)c1C)C1CCC(N(C)C)CC1 +CCN(c1nc(C)cc(C)n1)c1ccc(C(C)C)cc1Br +CCn1nc(C2CCN(CC3CN(C(C(=O)O)C4CCCCC4)CC3c3ccccc3)CC2)cc1Cc1ccccc1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NS(=O)(=O)CCN3CCOCC3)no2)cc1C#N +CC(C)(C)C1(c2ccccc2)OCCC(CCNCc2ccccc2)O1 +O=C(c1ccccc1)N1CCC(n2cnc3cnc4[nH]ccc4c32)CC1 +CC12CCOCC1C1(COC(N)=N1)c1cc(-c3cncc(Cl)c3)c(F)cc1O2 +Cn1c(=O)c2c(nc3n2CCCC(=O)N3CCCN2CCN(c3ncccn3)CC2)n(C)c1=O +CCOc1ccc(-n2c(C)c3c(C)nnc(-c4cccc(OC)c4)c3c2C)cc1 +NC(=O)c1cc(CNCCN2CCNC2=O)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +COc1ccc(-c2cnc(Nc3ccc(C4CNCCO4)cc3)nc2)cc1OC +Cc1cn2cc(C(F)(F)F)cc2c(C#Cc2cccc(F)c2)n1 +CN1CCN(C(=O)CNc2c(C(=O)C3CC3)cnc3ccc(-c4ccc(O)c(Cl)c4)cc23)CC1 +COc1ccccc1N1CCN(CCCCNC(=O)C(C)(C)C)CC1 +O=C1C2C3C=CC(C3)C2C(=O)N1c1ccc(F)c(Cl)c1 +Nc1nc(OC2CCCC2)nc2c1ncn2C1OC(CO)C(O)C1O +CCCc1c(C#N)cn(-c2ccc(C(=O)O)cc2)c1C +COCc1cc(-c2ccc3c(c2)C2(N=C(C)C(N)=N2)C2(CCC(OC)CC2)C3)cc(C#N)c1F +COc1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)N(C)CC(C)C)CC3)c2)c1 +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2NC2CCCC2)C1 +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(Cl)cn3)CC2)CC1c1ccc(F)c(Cl)c1 +CCC(c1ccc(-c2cccc(OC)c2)cc1)n1ccnc1 +Cn1c2c(c3ccc(-n4ccc(OCc5ncc(Cl)cc5Cl)cc4=O)cc31)CCNCC2 +Cc1nnc(C(C)C)n1C1CCN(C(C)CC(NC(=O)C2CC(F)(F)C2)c2ccccc2)CC1 +CCOCCCNC(=O)c1cc(NC(=O)Nc2cccc(Cl)c2)ccc1N(C)C +CCOC(=O)c1cc2cc3c(cc2nc1NC(=O)Nc1ccc(Br)cc1)OCO3 +O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)N1CCC(c2cccs2)CC1 +CC(C)c1csc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)n1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccncc3)nc2n1 +CC1=C(CNS(C)(=O)=O)C2=C(C)C3(CC3)C(C)(O)C(=O)C2=C1 +COc1ccc(-c2cc3c(NC(C)c4ccccc4F)ncnc3o2)cc1 +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)N4CCC(CCC(=O)NO)CC4)ccc3OCC)nc12 +COc1cc2c(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)ncnc2cc1C +CCCCN(CC)c1nc(C)nc(N(CC)c2ccc(C(C)C)cc2Br)n1 +O=C(C=Cc1cc(C(=O)c2ccc(F)cc2)cn1-c1ccccc1)C=C(O)C(=O)O +CN(C)CC=CC(=O)Nc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2cn1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(Cl)cc1CN1CCC(F)(F)CC1 +COC(O)=C1C(C)=NC(C)=C(C(=O)OCCSc2ccccc2)C1C +Cc1cc(F)ccc1C(=O)c1sc2cc(O)ccc2c1Oc1ccc(C=CC(=O)O)cc1 +O=C(NC1CCN(Cc2ccccc2)CC1)c1cc2nc(-c3ccc(Cl)s3)cc(C(F)(F)F)n2n1 +COCC1(CNc2nc(C)c(-c3nc4c(C)nccc4s3)c(NC3CC(C(C)(C)O)C(O)C3O)n2)CC1 +CC(C)(C)OC(=O)N1CCC(C(=O)NS(=O)(=O)c2c(Cl)sc(Cl)c2Br)CC1 +COc1ccc(C(=O)Nc2sc(Nc3ccc4ncccc4c3)nc2C(N)=O)cc1 +CSCCC(NC(=O)c1ccc(NCc2cccnc2)cc1-c1ccccc1C)C(=O)O +Cc1cc(C)c(-n2cc[n+](CC(=O)c3ccc4ccccc4c3)c2)c(C)c1 +NC(=O)N1CCCc2cc(-c3cncc(OCc4cccnn4)c3)cnc21 +CC(C)(Cc1ccccn1)N1C(=O)c2ccccc2C1C(=O)NCc1ccc(OC(F)(F)F)cc1 +CCC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)CC1 +Cc1cc(C(=O)Nc2cncc(C(=O)c3cn(C(C)C)c4ncncc34)c2)nn1C +O=C(O)C(Cc1ccc(OCc2ccccc2)cc1)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Cc1ccc(N(CCN2CCC(OCC(=O)O)CC2)C(=O)c2ccc(Cl)cc2)cc1 +O=C(NCc1cccc(-c2nn[nH]n2)c1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 +CCC(CC)C(=O)Nc1ccc(-c2nnc(-c3ccc(OC)cc3)o2)cc1 +Cc1cc2c(NC(=O)NC3CCC(c4nc(C)cs4)C3)c(F)ccc2cn1 +C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(S(C)(=O)=O)ccc3n2Cc2cccc(C(=N)N)c2)cc1 +COc1cc(OC)cc(N(Cc2cn(CCO)nn2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +N#Cc1cc(-c2ccnc(Nc3ccc(NC(=O)CC4CCC(O)C4)nc3)n2)cnc1N1CCC(F)C1 +c1cnc2[nH]cc(-c3ccnc(N4CCCC4)n3)c2c1 +CCOc1nc2cc(Br)ccc2c2[nH]c(-c3ccccc3Cl)nc12 +COC(=O)c1c(NC(=O)CSc2cccc(OC)c2)cnn1CCc1ccccc1 +CNc1nc(Nc2cn(C(C)(C)CC#N)nc2C)ncc1C(F)(F)F +O=C(CO)N1CCC(c2n[nH]c(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1 +CC(C)=CCc1cc(C(=O)Nc2cc3ccc(OCCCN(C)C)c(C)c3oc2=O)ccc1O +COc1ccc2ccccc2c1C1CC(Cl)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +O=C(O)C1CCN(c2cc3cccnc3c(-c3cccc(F)c3)n2)CC1 +Cn1cc(O)c(=O)cc1CNCCNc1ccnc2cc(Cl)ccc12 +Cn1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC(O)C3)n2)cn1 +O=C(C(=O)c1ccc([N+](=O)[O-])cc1[N+](=O)[O-])c1ccccc1 +Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1Cl +N=C(N)c1ccc(O)c(CN2CCC(NS(=O)(=O)c3cc4ccncc4s3)C2=O)c1 +CCc1c(C)[nH]c2c(-c3cnn(-c4cc(CO)ccn4)c3)cnn2c1=O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc(N)ccc1c2[Si](C)(C)C +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(F)cc1)C(=O)C(C)Cl +O=C(O)C(O)C1CCCN1CCC=C(c1ccccc1)c1ccccc1 +Cc1nn(CC(F)(F)CCO)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2 +O=C1Cc2cc(N3CCCCC3)c(NC(=O)c3cnn4cccnc34)cc2N1 +CCOc1cc2c3c(c4ccc(O)cc4c2cc1OCC)CC1CCCN1C3 +CC(C)(NC1CCC(C(=O)N2CCN(c3ccc(Cl)cn3)CC2)C(c2ccsc2)C1)c1ccc(Cl)cc1 +CNC(=O)c1ccccc1Sc1ccccc1[N+](=O)[O-] +CN1CC2CC1CN2Cc1nc2c(oc3ccc(Br)cc32)c(=O)[nH]1 +NS(=O)(=O)c1ccc2nc(-n3cc(C(=O)O)c(-c4ccc(F)cc4)n3)sc2c1 +Cc1ccc(OC(=O)c2cccc([N+](=O)[O-])c2)c(-n2nc3ccccc3n2)c1 +CC(C)Oc1ccc2c3c1OC1C(=O)CCC4(NC(=O)C=Cc5ccc(Cl)cc5)C(C2)N(CC2CC2)CCC314 +O=C(Nc1cc2ccc(-c3ccccc3Cl)nc2cn1)C1CC1 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3ccc(N)c(OCC(F)(F)F)c3)C2O)c1 +NC(=O)Nc1sc(-c2ccc(Cl)c(Cl)c2)cc1C(=O)NC1CCCNC1 +CCC(CC)(C(=O)O)c1ccc2c(c1)OCC(Cc1ccccc1)C2O +CCc1c(CC(N)=O)c2cc(OCCCC(=O)O)ccc2n1Cc1ccccc1 +O=C(c1nn(C2CCCN(CCC3CCOCC3)C2)c2c1CS(=O)(=O)c1c(F)cccc1-2)N1CCOCC1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2Cc1ccccc1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)C(F)(F)F)c12 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCC(F)(F)C2)c(-c2cncnc2)c1 +Cc1cc(-c2cccc(F)c2)cc(CNc2c(F)ccc(OCC(=O)O)c2C)c1C +Cc1cc(NCc2ccccn2)c2nc(N3CCOCC3)cc(=O)n2c1 +C=CCCCON=C1C(=O)N(Cc2nc3ccccc3n2CCCOC)c2ccccc21 +CC(=O)NC1CCC(C(C)C(N)C(=O)N2CCC(F)C2)CC1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CN2CCCC2)cn1 +Oc1cc(O)n2ncc(-c3ccc4c(c3)OCO4)c2n1 +O=C(NO)c1ccc(-c2ccc(CN3CCc4ccccc4C3)cn2)s1 +Cc1ccc(S(=O)(=O)OCCC2OC3(CCN(Cc4ccccc4)CC3)c3ccccc32)cc1 +CCCCNC(=O)C(C)CC(O)C(N)CC(C)(C)CCc1cccc2ccccc12 +CCCCc1nc(Cl)c(CNC(=O)OCC)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cc1ccc(CNCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(O)CCc2ccccc2)c(C)c1 +N#Cc1nc(C(=O)NCC(=O)O)c(O)c2ccn(Cc3ccccc3)c(=O)c12 +c1cc[n+](CCCCCCCCCC[n+]2cccc3ccccc32)cc1 +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2cc(Br)ccc21 +CC(Nc1nc2c(S(=O)(=O)c3ccc(Cl)cc3)nnn2c2ccsc12)c1ccccc1 +CCn1nnnc1Cc1ccc2[nH]cc(CCN(C)C)c2c1 +CCCCC(=O)NCc1ccc2c(cnn2-c2ccc(F)cc2)c1 +O=C(NCCc1cccc(Cl)c1Cl)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +COc1ccc(CC(=O)O)cc1-c1noc(-c2ccccc2)c1C(=O)NCCOc1ccc(Cl)cc1Cl +Cc1ccc2c(n1)CCN(c1ncnn3c(C)nc(C4CCOC4)c13)C2 +Cc1cc(NCCN2CCOCC2)c2ccc3ccccc3c2n1 +O=C(c1ccc(Oc2ncccc2C2CCCCO2)cc1)c1nc2ccccc2[nH]1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2ccc(C(C)C)s2)CCCCC1 +CC(NC(=O)Nc1cc2[nH]nc(Nc3ccc(F)cc3)c2cn1)c1ccccc1 +CC(C)(N)c1ccc(-c2nc(Nc3ccc(OCCN4CCOCC4)cc3)ncc2C#N)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1NC1CCC(NC(=O)C2CC2)CC1 +Cc1cc(N2CCN(C3CNC(C(=O)N4CCSC4)C3)CC2)n(-c2ccccc2F)n1 +CN1CCN(c2ncn(-c3ccc(Nc4nccc(-c5cc(F)cc(N6CCOCC6)c5)n4)cc3)n2)CC1 +N#Cc1nc(-c2ccnc(Nc3ccc(NC(=O)CN4CCOCC4)nc3)n2)ccc1N1CCC2(COC2)C1 +CC(=O)Nc1ccc2c(c1)N(C)C(=O)C(NC(=O)c1cc(Cc3ccccc3)on1)CO2 +CC(CN)c1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1F +NC(=O)N1CCCc2c1ncc(-c1cncc(CN3CCOCC3=O)c1)c2F +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CN(S(=O)(=O)c2ccccc2)C1 +CCc1cc(-c2noc(-c3ccc(C)c(CN(C)CC)c3)n2)cc(C)c1OCC(O)CNC(=O)CO +COCCN(C)c1cc(-c2c(C)cccc2C)nc2c1CN(c1cc(C(C)C)ccc1C)CC2 +O=C(Nc1cnn(Cc2cccc(Cl)c2)c1)c1n[nH]c2ccccc12 +CCCCCn1cc(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)c2ccccc21 +CNc1nccc(-c2cnc3c(NC4CCNCC4)nccn23)n1 +COc1cc2c(cc1-c1c(C)noc1C)[nH]c1ccnc(-c3c(C)noc3C)c12 +c1ccc(OCCCN2CCc3[nH]c4ccccc4c3C2)cc1 +O=C(NC1CC1)c1ccc(Cl)c(Oc2nncc3c2cnn3-c2ccc(F)cc2F)c1 +COc1ccc(Cc2cc(C3OC4(COC4)C(O)C(O)C3O)ccc2Cl)cc1 +O=C(Nc1cc(-c2ccc3cccnc3c2)ccn1)C1CC1 +COc1ccc(-c2nc3cnc(NCc4ccc(Cl)c(F)c4)nc3n(CCNC(C)=O)c2=O)cc1 +COC1OC2(c3ccc(CO)cc3)CCC3CCCCC31OO2 +CN1CCN(CCN=C(N)c2c(O)nsc2Nc2ccc(Oc3cc(Cl)ccc3Cl)cc2)CC1 +COc1cc2c(cc1O)ncc1c2c(-c2ccc(C#N)cc2)nn1C +O=C(Nc1ccc(OC(F)(F)C(F)F)cc1)c1cnc(N2CCC(O)C2)c(-c2cncc(F)c2)c1 +CCCC1(CCc2ccccc2)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)=C(O)O1 +COc1ccccc1-c1ccc(CC(NC(=O)C2(S(=O)(=O)C3CCCC3)CCCC2)C(=O)O)cc1 +CCN(CC)CCNc1cc(Nc2cc(C(C)C)[nH]n2)nc(NCc2cc(-c3ccccc3)no2)n1 +CCCn1c(=O)c2nc(NC(=O)c3ccc(S(=O)(=O)F)cc3)[nH]c2n(CCC)c1=O +Cc1cnc(COc2ccc3nc(C4CCCCC4C(=O)O)n(Cc4ccc(Br)cc4)c3c2)c(F)c1 +CCOC(=O)C(O)=CC(=O)c1cn(Cc2ccc(F)cc2F)c2ccccc2c1=O +COc1cc(C(=O)NN2c3ccc(Cl)cc3N=C(N3CCN(C)CC3)c3cc(Cl)ccc32)cc(OC)c1OC +NC(=O)c1nn(-c2ccc(S(N)(=O)=O)cc2)c2c1CCc1cnc(NC3CCCC3)nc1-2 +CC(C)(C)COc1cc(C(C)(C)C)ccc1CN=C(S)NCc1ccc(NS(C)(=O)=O)c(F)c1 +CCN(CC)c1nc2ccc(C(O)(c3ccc(C(F)(F)F)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 +Cc1cccc(CC(=O)Nc2n[nH]c3ccc(N4CCCS4(=O)=O)cc23)c1 +COc1ccc(-c2nc(-c3ccnc(C)c3)c3n2CC(C)OCC3)cc1OC(F)(F)F +N#Cc1ccc(C(=O)N2CCN(c3ccc(OCCCN4CCCCCC4)cc3)C(=O)C2)cc1 +Cn1c2c(c3ccccc31)CN(CCCOCc1ccccc1)CC2 +COc1ccc2c(Cc3c(Cl)cncc3Cl)nncc2c1C#CCCCc1ccccc1 +O=C1NC(=O)C2(CCC(=O)N2c2ccc(Oc3ccc(F)cc3)nc2)C(=O)N1 +CC(C)Nc1ccc(Nc2ccnc3cc4ccccc4cc23)cc1 +NC1(c2ccc(-c3nc4c5cc(-c6ccn[nH]6)ccc5nn4cc3-c3ccccc3)cc2)CCC1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4cccc(F)c4F)nc23)N1 +Cc1cc(C(=O)N(Cc2ccccc2)c2ccc(-c3nc(Cl)ncc3C)cc2)c(O)cc1O +CN(C)C(=O)N1CC=C(c2cc3c(-c4cccc(NC(=O)c5ccc(C6CC6)cc5)c4CO)ncnc3[nH]2)CC1 +COC1CCC2(CC1)Cc1ccc(C#N)cc1C21N=C(N)N(CCc2nccs2)C1=O +O=C1CCc2ccccc2N1CCCN1CCC(CCCCCCCO)CC1 +COc1ccc2c(c1)C(=O)C(c1ccc(OC)c(C)c1)=[N+]2[O-] +NS(=O)(=O)c1c(F)c(F)c(SCc2ccccc2)c(F)c1F +Cn1cc(C2(c3cnn(C)c3)NC(c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 +COc1ccc(CC(=O)NC(Cc2c[nH]c3ccccc23)CN(Cc2ccccc2OC)C(C)=O)cc1 +CSc1nccc(-c2c(-c3ccccc3)nc3nc(N)ccn23)n1 +Cc1cc(NC(=O)c2nn(C)c(-c3ccc(F)cc3)c2C)ccn1 +CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(OCCCC(=O)NO)cc1 +Fc1ccc(-c2[nH]c(SCc3ccccc3)nc2-c2ccnc(NCc3ccccc3)c2)cc1 +O=C(NCc1ccc(N2C3CCCC2CC3)c(F)c1)Nc1cccc2[nH]ncc12 +CON=Cc1c(N)ncnc1Oc1ccc(NC(=O)NCCN(C)C)c(Cl)c1 +CC(CN(C)C)NC(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1F +O=C1CN=C(n2cnc(C3CC3)c2)C=C2c3cccc(-c4ccno4)c3CCN12 +COc1cc(Nc2c(C(N)=O)cnc3c(Cl)cc(S(C)(=O)=O)cc23)ccc1F +CN(c1ccc(-c2ccncc2)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +COc1ccc2[nH]cc(C(=O)c3cc(OC)c(OC)c(OC)c3)c2c1 +NC(=O)c1cccc2c(NC(Cn3ccnc3)c3ccccc3)ncnc12 +CC(=O)NCCc1ccccc1-c1onc(C2CNCCC2(O)c2ccc(F)c(F)c2)c1Cl 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+O=C(Nc1cccnc1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +COc1cc2ncc(C#N)c(Nc3cccc(Br)c3)c2cc1OC +Cc1nc2ccccn2c1-c1csc(Nc2ccc(O)cc2)n1 +O=C1CCc2ccc(OCCCCN3CCN(c4cccc5c4OCCO5)CC3)nc2N1 +CC(=O)N1C2C=C(CN3CCC(NC(=O)Nc4cc(F)cc(OC(C)C)c4)CC3)CC1CCC2 +COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(Cl)cc1 +O=C1OC(c2ccc(O)c(Br)c2)(c2ccc(O)c(Br)c2)c2cccc3cccc1c23 +c1ccc(CNc2ncccc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)nc1 +CC1OC(n2cc(C(=N)S)c3c(N)ncnc32)C(O)C1O +O=C(NO)c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)s1 +CC(=O)N1CCc2c(c(Nc3cccc(-c4ccncc4)c3)nn2CC2CC2)C1 +Cc1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)NCCCC(=O)O)sc2ccccc12 +O=C1c2cccc3cc4ccccc4c(c23)C(=O)N1CCNCCO +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(-c5ccc(C)nc5)ccn34)c12 +COc1ccc(-c2ccnc3cc(-c4cccc(Cl)c4)nn23)cc1OC1CCCC1 +Cc1ccc(C(C)Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)nc1 +O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)N=C(N1CCC(F)(F)CC1)c1ccccc1S2 +Cc1cc(C(=O)NC(CCC(=O)O)C(=O)O)sc1CCCSc1c(N)nc(N)nc1O 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+CCN(CCCCCCNC1=CC(=O)C(NCCCCCCN(CC)Cc2ccccc2)=CC1=O)Cc1ccccc1 +O=C(CC(F)(F)F)NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1 +Clc1ccc(-c2ccc(-c3cc(-c4nnn[nH]4)nn3-c3cccnc3)cc2)c(Cl)c1 +CCCCn1c(=O)c2cc3nc[nH]c3cc2n(CCCC)c1=O +CCNc1nc(-c2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2C)cc(N2CCOCC2)n1 +CCc1nc2cc(CN3CCC(NC(=O)c4cc(=O)c5ccc(F)cc5o4)CC3)ccc2o1 +CNC(=O)C(NC(=O)C(CC(C)C)C(Sc1ccccc1)C(=O)NO)C(C)(C)C +COc1ccc(S(=O)(=O)c2ccc(C)nc2Nc2c(C)cc(C)cc2C)cc1 +C=CC(=O)Nc1cc2c(Nc3ccc(F)cc3F)ncnc2cc1OCCNC(=O)CN(C)C +Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)CCCCC4CCSS4)ccc3n(C)c12 +O=C(c1ccc(F)c(O)c1)c1cccc(N2CCCCC2)n1 +CCn1cc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cn1 +COC(=O)N1CC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +O=C(CN1CCOCC1)N1CCc2nc(-c3cc4ccccc4[nH]c3=O)[nH]c2C1 +CNC(=O)c1ccccc1Nc1nc(Nc2ccc(NS(=O)(=O)c3ccc(F)cc3)c(OC)c2)ncc1Cl +COCCC1(c2nc(NC(=O)c3ncc(C#N)cc3C)ccc2F)N=C(N)OCC1(F)F +CCOC(=O)c1cc(-c2cc(O)c(Sc3ccccc3C(C)C)c(=O)o2)ccc1O +CC(O)CN(C)c1nc2cc(-c3ccccc3)nnc2c2ccccc12 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+O=C(Nc1ccc(F)cc1)NC1C(=O)N(CCN2CCOCC2)c2ccccc2N(CC23CC4CC(CC(C4)C2)C3)C1=O +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1cccc(F)c1F)NCC3 +CCc1cc(Nc2nc3ncn(CCCCCOC)c3c(=O)[nH]2)ccc1C +CCCn1c(=O)c2nc(C3CCCC3)[nH]c2n(CCc2ccc(NC(=O)C(C)C)cc2)c1=O +COc1ccccc1C(C#N)NC(=O)C1CCCCC1C(=O)N1CCN(Cc2ccc(F)cc2)CC1 +CC1CCC(C(=O)Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)CN1 +O=C(NCCCCN1CCc2ccc(OS(=O)(=O)C(F)(F)F)cc2C1)c1ccc(-c2ccccc2)cc1 +CCc1ccc(-c2ccc(C(=O)N(C)C3CCN(C(=O)N(C)C4CCN(C)C4)C3)s2)cc1 +O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccccc1 +N#Cc1ccc(-c2ccc(CC(N)C(=O)N3CCSC3)cc2)cc1 +Oc1ncccc1C(C#CC1CC1)(OCc1ccccc1)C(F)(F)F +COC(=O)CN1CCN(C(=O)CNC(=O)c2ccc(C(=N)N)cc2)C(CC(=O)O)C1=O +Nc1ncc(-c2ccccc2)cc1-c1nc2ccccc2[nH]1 +CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C[N+](=O)[O-])CCC43O)C2)C(O)C(O)C1O +Cc1ccc(S(=O)(=O)N2CC3(CC2C(=O)NO)SCCS3)cc1 +CC(C)(C)NCC(=O)Nc1cc(CO)cc(Nc2ccnc3cc(Cl)ccc23)c1 +CC(C)n1c2cnccc2c2cnc(Nc3ccc(N4CCC(N(C)C)CC4)nn3)nc21 +N#Cc1c(N2CCN(c3ncccn3)CC2)ccn2c(CC(F)(F)F)cnc12 +O=C(C1CC(N2CCN(c3noc4ccccc34)CC2)CN1)N1CCC(F)(F)C1 +CCCC1(O)CCN(C(=O)CC2(C3CCCC(CC)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1 +O=C1OCc2c1cc1ccc3c(c1c2-c1ccc2c(c1)OCO2)OCO3 +Cc1nnc(C(C)C)n1C1CC2CCC(C1)N2CCC(C)(CNS(=O)(=O)c1ccccc1)c1ccccc1 +CCCS(=O)(=O)Nc1cccc(-c2[nH]c(C(C)(C)C)nc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +Cn1cc(-c2ccc(-c3cnc(N)c4ccc(C(=O)NC5CC5)cc34)cc2)cn1 +Cc1ccc(Cl)cc1-n1cc(-c2ccnc(N)n2)cc1C(N)=O +Cc1nc(C)c(-c2ccc3c(c2)CCC32CCC(C(=O)O)CC2)nc1C(N)=O +CN(C)c1ccc(C=CC(=O)c2ccc(F)cc2)cc1 +C=C1CCCC2C1(C)CCC(C)C2(C)CC=C1C(OC(C)=O)OC(OC(C)=O)C1OC(C)=O +CC(C)n1cc2c3c(cccc31)C1=CC(CO)CN(C)C1C2 +CCOC(=O)c1c(Nc2cccc(Cl)c2)[nH]c2ccc(O)cc12 +CC1CCC(NCc2ccc3c(c2)Cc2c(-c4ccc(F)cc4)n[nH]c2-3)CC1 +COCC(NC(=O)C(NC(=O)C(CCCc1ccccc1)CC(=O)NO)C(C)(C)C)c1ccccc1 +O=C(Nc1ccc2c(cnn2CCN2CCCC2)c1)NC1CCN(Cc2ccccc2)CC1 +O=C(C1CC(Oc2cccc(F)c2)CN1C(=O)C1CC1)N1CCCN(C2CCC2)CC1 +O=C1CC(c2ccccc2)CN1c1cccc(N2CCNCC2)n1 +CCC(O)(c1cccc(F)c1)C1CCC(N2C(=O)Cc3cc(OC)c(OC(C)C)cc3C2c2ccc(Cl)cc2)CC1 +CC(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc3[nH]ccc3c2)c(F)c1 +Cn1c(=O)c2c(nc(OCc3ccccc3)n2C)n(C)c1=O +CC(C)N1CCC(N(C)C(=O)Cn2c(-c3ccccc3)c(C3CCCCC3)c3sc(C(=O)O)cc32)C1 +CNC(=O)c1cc(I)cc(C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl +O=C(NC1CCCC1NC(=O)c1cc2ccc(Cl)cc2s1)c1ccc(-n2ccccc2=O)cc1 +NC1=NC(CF)(c2cc(NC(=O)c3ccc(Br)cn3)ccc2Cl)C2CC2O1 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3S(C)(=O)=O)c1C +O=c1[nH]c2cc(CNS(=O)(=O)c3ccc4ccccc4c3)ccc2n1-c1cc(Cl)c(O)cc1O +CC1CN(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)CCO1 +O=C1Nc2ccccc2C1=C1Nc2ccc(C(=O)O)cc2C1=NO +Nc1ccnc2sc(S(=O)(=O)c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c12 +CN1CCN(C(=O)N(C)c2ccc(NC(=O)c3ccc(C#N)o3)c(N3CCCCC3)c2)CC1 +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)c1F +OCCCNc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1Cl +CCc1ncnc(-c2cc(Cl)c(C(=O)N3CCN(CC(C)(C)O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +c1ccc(CN2CCC3(CC2)OCCc2c3csc2-c2ccccc2)cc1 +Cc1ccc(O)c(Cn2c(NC3CCN(CCN)CC3)nc3c(C)cccc32)n1 +O=C1c2ccc(O)cc2C23CCCCC2C1N(CCCF)CC3 +CCOC(=O)C1=C(C)Nc2nc3c(c(N)c2C1c1ccc(OC)c(OC)c1)CCCC3 +CN(C)C1CCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(NCc2cccc(C(F)(F)F)c2)C1 +CC(=O)c1cc2ccc(OS(=O)(=O)C(F)(F)F)cc2oc1=O +CC(=O)Oc1ccc2c(c1)C1c3cc(OC(C)=O)ccc3C(C2)N(C)C1C +Cc1[nH]cnc1CCNC(=O)CN1CCN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC1=O +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1)c1cccc(C(=N)NO)c1 +COc1ccc2occ(C(=O)Nc3ccc(Cl)cc3)c(=O)c2c1 +O=C(N1CCCC2(CCc3ccccc32)C1)C1(c2ccc(Cl)cc2)CC1 +CC(C)(C)NCCOc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +Cc1c(N(Cc2ccc(OCC3CC3)c(F)c2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +Cn1c(=O)c2c(CCC(=O)Nc3ccccc3C(=O)O)nnn2c2ccc(O)cc21 +CCC(=O)Nc1ccc2c(c1)N(Cc1cc(F)cc3c1OCOC3)C(=O)C2=NO +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5nonc5c4)c3c2)C1 +CS(=O)(=O)N1CC2(CCN(C(=O)Nc3ccc(-n4nccn4)cc3)CC2)c2ccccc21 +Cn1cc(S(=O)(=O)C2CCC(CNC(=O)c3ccc(Cl)cc3Cl)(CC3CC3)CC2)nn1 +CCCn1c(=O)[nH]c2nc(-c3cnn(Cc4cc(-c5ccc(Cl)cc5)on4)c3)[nH]c2c1=O +O=C1N(Cc2cccc(O)c2)C(CCc2ccccc2)C(O)C(Cc2ccccc2)N1Cc1cccc(O)c1 +O=C(CN1CCCCC1)N1CCC(CNc2nc3c(s2)CCCc2ccccc2-3)CC1 +OC(CNc1nc2ccccc2[nH]1)CON=C(C1CC1)C1CC1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5CCC(C4)C5O)cn3)nc2n1C1CCCC1 +CCOC(O)=C1C(COCCn2ccnn2)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +CCCCCn1cc(C(=O)Nc2cccc(C(F)(F)F)c2)c(=O)cc1-c1ccccc1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(Nc3ccccc3)nc(-c3ccccc3)n2)CC1 +CCCCCCOc1cccc(OCCCCNC(=O)NC(CC(=O)[O-])C[P+](C)(C)C)c1 +COc1ccc(NC(=O)c2ccc(NS(=O)(=O)c3ccc4c5c(cccc35)C(=O)N4)cc2)cc1 +Cc1ccc(-c2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)c(N)c1 +CC(C)CC(NC(=O)C(N)Cc1ccccc1F)B(O)O +O=C(NCC1CCc2cc(Br)cc3[nH]c(=O)c(=O)n1c23)c1ccccc1 +O=c1[nH]c2ccccc2c(=O)n1CCN1CCC(Cc2ccccc2)CC1 +COc1cc(C=CC(=O)OCCCCOc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)ccc1O +CCCCOC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +CN(c1ncnc2[nH]ccc12)C1CC(NS(=O)(=O)CCCC#N)C1 +CCCCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(F)c4)c3)nc2n(C)c1=O +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)c(Cl)c3)nc(C(C)O)c12 +CC=C1C2C=C(C)CC1(N=Cc1ccc(O)c(OCC)c1)c1ccc(=O)[nH]c1C2 +COCCOC(=O)N1CCC2C(CC3C(=O)OC(C)C3C2C=Cc2ccc(-c3cccc(F)c3)cn2)C1 +COc1cc2nccc(Oc3ccc(-c4cnc(Nc5cccc(F)c5)n(C)c4=O)cc3F)c2cc1OC +Cc1cccc(C)c1NC(=O)CSCC1CCCN2CCCCC12 +N#Cc1ccc(OCCCN2CCC(C(O)(c3cccc(F)c3)C3CCCC3)CC2)cc1 +CCNC(=O)c1ccccc1C1CC2CCC(C1)N2C(=O)C(CCCc1ccccc1)NC(=O)C(C)(C)N +O=C(O)C=Cc1ccccc1C=CCc1ccccc1Oc1ccccc1 +Cc1ccc(-c2csc3ncnc(SCCC(=O)O)c23)cc1C +CC(OC1CN(C2=CC(=O)CC2)CC1c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +NCCCCN(Cc1nccc2c3ccccc3n(CC(=O)N3CCC(O)CC3)c12)C1CCCc2cccnc21 +CC12CCC3c4ccc(OS(N)(=O)=O)cc4CCC3C1CCC2(O)Cc1ccc(O)cc1 +O=C(NN=Cc1cc(Br)c(O)c(Br)c1)c1cc2c(ccc3ccccc32)o1 +CCCCOc1nc(N)c2[nH]c(=O)n(CCCCCC3CCNCC3)c2n1 +CC(C)(COc1cccc2ccc(-c3nnc4ccccn34)nc12)C(O)CO +CC(CC(N)=O)(NC(=O)c1cc(OCC(F)(F)F)c(N2CC(F)(F)C2)cn1)C1CC1 +C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OCCOC +CC1(c2cccc(NC(=O)c3ccc(Cl)cn3)c2)N=C(N)Cn2nccc21 +COc1cc2c(cc1F)N(Cc1ccccc1)CC(C)N(C(=O)Nc1cccnc1)C2C +COc1ccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cc1C +O=C(NCC1(c2ccc(F)cc2)CCC1)C1CCN(Cc2ccccc2)CC1 +Cn1cnc2cc(-c3ccc(S(C)(=O)=O)cc3)nc(NC3CCC3)c2c1=O +COC(=O)CC(c1ccc(OC)nc1)N(C)C(=O)CCCCc1nc2c(cc1Br)CCCN2 +CCN(CC)C(=O)N1CCC(CCC(=O)Nc2ccc(F)c(F)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +CCOC(=O)CCCCON=C(c1cccnc1)c1ccccc1C(=O)N1CCN(C(=O)C2CSC(c3cccnc3)N2)CC1 +CCOc1ccc(C(=O)N2CCN3C(=O)c4ccccc4C23c2ccc(Cl)cc2)cc1 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(C)CC4)ncn3)c2c1 +COc1cc(-c2cc(F)cnc2OC)c(F)cc1-c1nccc2cc(S(=O)(=O)Nc3ccon3)ccc12 +CC(=O)N1CCC(c2nccnc2OC2CCC(Nc3nc4ccccc4s3)CC2)CC1 +COc1cc(OCC2COC(C)(C)O2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CN(CCCCN1C(=O)CSC1c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)CCOc1ccc2c(c1)OCO2 +CC(C)C(CNC(=O)c1cccnc1Oc1ccc(Nc2ccccn2)cc1)c1ccccn1 +CC(C)(C)NCC(O)CON=C1c2ccccc2C2CCCCCC12O +CC1(C)CCc2[nH]nc(C(=O)Nc3cnn(Cc4ccccc4)c3)c2C1 +O=C(NOCC(O)CO)c1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +CC1=CC(C)(C)Nc2ccc3c(c21)C(c1ccc(Cl)c(Cl)c1)Oc1ccccc1-3 +COc1cccc2cc(C(=O)NCCC3CCN(Cc4ccccc4)CC3)c(=O)oc12 +CCNCCNc1cc(-c2ccc(C(F)(F)F)cc2)c(C#N)c2nc3cc(Cl)c(Cl)cc3n12 +Cc1ccc(C#N)cc1S(=O)(=O)N(C)CCc1cnn2ccc(Cl)nc12 +CN(C)CCCNc1[nH]nc(N)c1-c1nc2ccccc2s1 +CCS(=O)(=O)c1ccc(Oc2cc3nc(-c4ccccn4)[nH]c3cc2CN2CCCC2=O)cc1 +NS(=O)(=O)c1cc(-c2cnc(C3CCC3)o2)cs1 +OC(CC1c2c(F)cccc2-c2cncn21)C1CCCCC1 +CC(C)S(=O)(=O)c1ccn(C(CC2CCCC2)C(=O)Nc2ccn(C)n2)c(=O)c1 +Cn1c(=O)cnn(CCCCN2CCN(c3ccccc3S)CC2)c1=O +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCCCCCCNC(=O)C2CN(C)CCC2c2ccc(Cl)cc2)C1 +COc1c(C(=O)NC2CC3CCCC(C2)N3C2CCCCCC2)cc(Br)c2ccccc12 +Oc1ccccc1-c1cccc(-n2nnc(-c3ccccn3)n2)c1 +CN1C(=O)C(=N)c2c3ccccc3c(O)c3c(Br)ccc1c23 +CC1(CCCc2cc(=O)oc3nc(C(F)F)[nH]c(=O)c23)CC1 +CN1CCN(c2ccc(C(=O)Nc3cccc(CNc4ncnc5c(C(N)=O)cccc45)c3)cc2)CC1 +O=C(NC1COCCC1NC1CCCC1)c1ccc(C(F)(F)F)cc1C1CC1 +COc1cc(OC2CCN(Cc3cccnc3C)CC2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +N#Cc1ccc(-c2cccc(S(=O)(=O)N3CCC(N4CCCC4)CC3)n2)cc1 +COc1ccc2nc3cc(Cl)ccc3c(NCc3ccc4c(c3)OCO4)c2c1 +CCCc1nc(C)n2nc(S(=O)(=O)NC)nc2c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(Cn1ncc2c(=O)oc3ccccc3c21)Nc1ccc2ccccc2c1 +Cn1c(-c2cccc(-c3ccccc3)c2)ncc(O)c1=O +Cc1cccc(-c2ccnc(C(=O)Nc3ccc(Oc4ccnc5[nH]ccc45)c(F)c3)c2)c1 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+CCN1CCCC1CNC(=O)c1cc(I)cc(OC)c1OCCF +Cc1ccc(Oc2cn(C)c(=O)c(Nc3ccc(C(F)(F)F)cc3)n2)c(C)c1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(I)cc1-c1ccn[nH]1 +O=c1cc(-c2ccc(O)c(O)c2)oc2c(C3OC(CO)C(O)C(O)C3O)c(O)cc(O)c12 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CCCc2ccccc2)C(=O)CO)c1 +COc1cc(NC(C)CCCNCC2CCC3(CC2)OOC2(OO3)C3CC4CC(C3)CC2C4)c2ncccc2c1 +Cc1ccc(-c2ncccn2)c(C(=O)N2CC(COc3ccc(F)cn3)CCC2C)c1 +O=C1NC(=O)C2=C(CCCC2)C1=Cc1ccc(Cl)cc1 +O=[N+]([O-])c1ccc2nc(N3CCNCC3)cc(-c3ccccc3)c2c1 +Cc1c(CCN2CCN(c3ccc(F)c(Cl)c3)CC2)c2cccc3c2n1CCC3 +COc1ccc(-c2ccc(C(N)=O)cn2)cc1OC1CCCC1 +Cc1cc(-c2nc3cnc(N4CCOCC4C)cc3n2Cc2ccccn2)cn(C)c1=O +COCCOc1cc2ncnc(Nc3ccc(OC4CCN(C(=O)CC(C)(C)C)CC4)c(C)c3)c2cc1OCCOC +CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3ccnc4ncc(=O)[nH]c34)c3ccccc23)n(-c2ccccc2)n1 +O=C1CCCc2nc(-c3ccco3)c3c(c21)C(=O)C=C(Nc1ccccc1)C3=O +O=C(CN1CCN(c2ccccc2)CC1)NC1c2ccccc2SCC2CCCCC21 +O=C(Nc1ccc(Oc2ncnc3[nH]cnc23)c(F)c1)c1cccn(-c2cccc(F)c2)c1=O +O=C(c1cccc([N+](=O)[O-])c1)c1ccc2ccc(C=Cc3ccc(O)c(O)c3)nc2c1O 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+O=C(CCCC(=O)NCCCCCCCNc1c2ccccc2nc2ccccc12)NCCCCCCCNc1c2ccccc2nc2ccccc12 +Cn1cc(CNc2cc(OCC3CC3c3ccc(Cl)cn3)nn(C)c2=O)cn1 +CN(CCc1ccccc1)C(=O)N1CC(OC(c2ccc(Cl)cc2)c2cccnc2Cl)C1 +Cc1cnc(-c2cc(C)c3nc(-c4c(NCC(O)c5cccc(Cl)c5)cc[nH]c4=O)[nH]c3c2)[nH]1 +COc1ccc(C=C2CNCC(=Cc3ccc(OC)c(OC)c3)C2=O)cc1OC +COc1cccc(-c2cc(C#N)cc3cc(C(N)(c4ccc(C#N)cc4)c4cncn4C)oc23)c1 +Cc1cc(COc2ccc(NC(=O)C3CCN(S(C)(=O)=O)CC3C(=O)NO)cc2)c2ccccc2n1 +COCCN(CCOC)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1SC +CCOc1ccc(N2C(=O)C(=Cc3ccccc3)N=C2SC)cc1 +NC(=O)C(NC1CCC(c2c[nH]c3ccccc23)CC1)C1CCN(C(=O)C=Cc2ccc(OC(F)(F)F)cc2)CC1 +COc1ccc(-c2ccc3nccc(Nc4cccc5[nH]ncc45)c3c2)cc1C=O +CC(C)(Cc1cc2ccccc2[nH]1)NCC(O)C1CCCN1Cc1cccc(C#N)c1 +N=C(N)c1ccc(CNC(=O)Cn2c(-c3cc(N)cc(C(=O)O)c3)c(Cl)nc(NCCCO)c2=O)cc1 +N#CC12CC3CC(C1)C(NC(=O)c1cnn4cc(CCO)cnc14)C(C3)C2 +O=C1NCCN1c1ccc(S(=O)(=O)Oc2ccccc2F)cc1 +CC(C)CS(=O)(=O)N1CCN(C(c2ccc(Cl)cc2)c2cncnc2)CC1 +O=c1sn(-c2cccc(Cl)c2)c(=O)n1Cc1ccc(F)cc1 +COc1ccc(-c2cc3cccc4c3n2CCNC4=O)cc1 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+O=C1NCC2c3c(cccc31)CCN2C(=O)C1CCCC1 +CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)N(CC)CCC(=O)O)n1 +Cc1c(Sc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)[nH]c2nc(N)nc(N)c12 +CC1(C)c2cc(N3CCOCC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +N=C(N)c1ccc(N2CCN(c3ccc(-c4nc5ccccc5[nH]4)cc3)CC2)cc1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(NC3CCN(C(=O)CO)C3)c2c1=O +COc1cc2c(cc1OC)C(=O)C(Cc1cccc(CN3CCCCC3)c1)O2 +COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccc(OCc3ccccn3)nc2c(=O)n1-c1ccc(N)cc1 +CCC(CN1CCS(=O)(=O)CC1)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CCOC(=O)c1cccc(-c2cnc3ccc(NC(CC)CO)nn23)c1 +O=c1c2cc(OCCCN3CCCC3)ccc2nc2n1CCCCC2 +CNC(=O)c1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 +CCC(C(=O)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1)c1ccccc1 +N#Cc1cc(C(F)(F)F)ccc1N1CCC(N(c2ccc(Cl)cc2)c2cccnc2)CC1 +CC1C(N)=NC(C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CCS1(=O)=O +CC1CCN(C(=O)Nc2nc3c(s2)-c2nc(C(C)(C)C(F)(F)F)ncc2CC3)C1C(N)=O +Cc1cc(S(C)(=O)=O)ncc1Nc1ncnc(OC2CCN(C(=O)OC(C)C)CC2)c1C +O=c1ncn2nc(Sc3ccc(F)cc3Cl)ccc2c1-c1c(Cl)cccc1Cl +CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 +CN1C2CCC1CN(C(=O)c1cc3cc(Nc4nccc(-c5ccccn5)n4)ccc3[nH]1)C2 +CCOC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1cccs1 +CC(c1ccccc1CN)n1c(=O)oc2cc(S(=O)(=O)Nc3cccc(F)n3)c(F)cc21 +CC(CO)Nc1cc(NS(C)(=O)=O)nc(SCc2cccc(Cl)c2F)n1 +CC(C)c1nnc(NC(=O)NC23CC4CC(CC(C4)C2)C3)o1 +CCOc1ccc2c(c1Cl)C(=O)N(Cc1c(C)cc(C)[nH]c1=O)CC2 +Cn1nnnc1SCC(=O)OCC1(C)C(C(=O)O)N2C(=O)C(=CC(=O)O)C2S1(=O)=O +COc1ccc(-c2snnc2-c2cc(OC)c(OC)c(OC)c2)cc1 +COC1CCC2(CC1)Cc1ccc(OCC3(C)CC3)cc1C21N=C(C)C(N)=N1 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(NCCC(O)CO)c(-c2ccn[nH]2)c1 +FC(F)(F)c1cc(Br)cc(Nc2nccc(-c3cnn4ncccc34)n2)c1 +CCCC(=O)Nc1n[nH]c2ccc(-c3cccc(F)c3F)cc12 +CCC(CC)CC1CN(Cc2c[nH]c3c(N)ncnc23)CC1O +COc1cc(O)cc(OC)c1C1CNC(C(=O)N2CCCC2C#N)C1 +CC1CCC2C(C)C(CCOC(=O)CCC(=O)O)OC3OC4(C)CCC1C32OO4 +CCc1nnc(-c2cc(C(=O)N3CCC(F)(c4ccc(C#N)cc4)CC3)ccc2C2CCC2)[nH]1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccc(F)cc2)c1 +CNC(=O)C=Cc1cnc(N)c2c(-c3cc(F)c4[nH]c(C)cc4c3)csc12 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+CS(=O)(=O)CCNCc1ccc(-c2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2)[nH]1 +Cc1cc(N)nc(COCC(N)C(C)OCc2cc(C)cc(N)n2)c1 +CC(C)(COc1ncc(-c2ccc(-c3ncc(C4(C(F)(F)F)CCC4)[nH]3)cc2)cc1F)C(=O)O +CC(C)NC(=O)c1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4ccc(=O)n(CCO)n4)ccn23)c1 +CCC(O)(CC)c1ccc(NC2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)nc1 +C#CCn1c(=O)n(C)c(=O)c2c1nc(N1CCCC(N)C1)n2Cc1ccccc1C#N +CCNc1nc(-c2ccc(S(=O)(=O)CC)cc2)cc2ncn(C)c(=O)c12 +CCCCc1ccc2[nH]c(-c3ccc(OC)cc3)c(C=NNC(=O)c3ccccn3)c2c1 +NC1CCC(Nc2cc(-c3cccc(NCc4cccc(OC(F)(F)F)c4)n3)c(Cl)cn2)CC1 +Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCCc1ccc(F)cc1 +CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCCC(F)(F)F)c3Cl)C2)cc1 +CCSc1nc2cc(S(=O)(=O)NCc3ccc(OC)cc3)ccc2n1Cc1ccccc1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(CNC(=O)C2CC2)Nc2ccccc2C(=O)c2ccccc2)cc1 +CCCCC(C=C1CC(CO)(COC(=O)c2ccc(C)cc2)OC1=O)CC +Cc1cccc(-c2[nH]c(CNc3ccc(OC(F)(F)F)cc3)nc2-c2ccc3ncnn3c2)n1 +CC(C)(C)OC(=O)NCCCNc1cccc2ccc(-c3nnc4ccccn34)nc12 +CC(C)(CC(=O)N1CCC(O)C1)NCC(=O)N1CC(F)CC1C#N +ON=Cc1cnn2ccc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)cc12 +Cc1cccc(NC(=O)NC2CC(c3ccccc3C)CC(c3ccccc3)N(CC(=O)NC(C)C)C2=O)c1 +CNc1c(C)c(C)nc2cc(C3CCCCN3C(=O)c3ccccc3NS(C)(=O)=O)nn12 +CONC(=O)c1ccc(C)c(Nc2ncnn3cc(NC(=O)NC(C)C)c(C)c23)c1 +COc1ccc(C(CC(=O)O)Nc2ncnc3c2CN(c2ccc(C)cc2C#N)CC3)cn1 +O=S(=O)(Nc1nccs1)c1ccc(Oc2cc(C(F)(F)F)nn2-c2cc(F)ccc2F)c(F)c1 +CC(C)C1C(=O)NC(CO)Cc2cc(NC(=O)C=CC=Cc3cc(C(F)(F)F)cc(C(F)(F)F)c3)ccc2N1C +CN(C(=O)Cc1ccc(C(F)(F)F)cc1)C(CN1CCCC1)c1cccc([N+](=O)[O-])c1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1c[nH]c2ccccc12)OCCc1c[nH]c2ccccc12 +CC1(C)Oc2ncnc(N)c2C=C1c1ccc2c(c1)CCC21CCC(CC(=O)O)CC1 +Cc1cc(C)n(CC2OC(n3cnc4c(Nc5ccc(Cl)cc5F)ncnc43)C(O)C2O)n1 +CNCCCOc1ccc(-c2ccc3ncc4c(c3c2)n(C2CCCOC2)c(=O)n4C)cn1 +CCOC(=O)c1ccc(CN2CC(C)(C)C(Oc3ccc(C#N)c(C(F)(F)F)c3)C2=O)o1 +CN(C)c1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)CCO3)cc1 +CCCc1[nH]c(=O)c(-c2csc(CS(=O)(=O)c3ccccc3)n2)cc1C(=O)OCC +CS(=O)(=O)c1ccc(C2SCCC(=O)N2Cc2ccccc2)cc1 +CC1CCCC(Nc2ncnc3c2nnn3Cc2ccccc2Cl)C1 +CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)NC1C(=O)N(C)N(C)C(=O)c2ccccc21 +CCN(CCCCCC(=O)N(C)CCCCCCCCN(C)C(=O)CCCCCN(CC)Cc1ccccc1Cl)Cc1ccccc1Cl +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(NCCN1CCC(c2ccccc2)CC1)c1ccccc1 +Cc1cn2cc(C(F)(F)F)cc2c(C#Cc2cccnc2)n1 +CCC(CC)Oc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +N=C(NC1CC1c1ccccc1)NC12CC3CC(CC(C3)C1)C2 +Cc1cc(C(=O)N2CC(OCC(N)=O)C2)cc2c1-c1ccccc1C2(O)C(F)(F)F +Cc1ccc(-c2c3n(c(=O)c4ncccc24)CCCCCN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C3=O)cc1 +COc1ccc2c(c1)C(=O)CC(CCN1CCN(c3ccccn3)CC1)C2 +CCCCOC(=O)C1=CCCCC1S(=O)(=O)Nc1ccc(F)cc1F +O=S(=O)(c1cc(Cl)cc(Cl)c1)c1ccc2oc3c(c2c1)CNCC3 +O=C(c1n[nH]c2c1CCN(CCC(F)(F)F)C2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1C=Cc2c(ncn2-c2cnccn2)C1 +COc1cc(CCNC(=O)C=C(C)C)c2[nH]c3ccccc3c3ccnc1c23 +COc1ccc(C2=NN(C(C)C)C(=O)C2(C)C)cc1OCc1cccc2ccccc12 +O=C(NC(CO)c1ccccc1)c1ccc(-c2ccncc2)cc1 +O=C1Nc2c(ccc(F)c2F)C1(c1ccc(O)cc1)C1CCCCC1 +O=C(O)CCNc1sc2c(c1Cc1nnc(S)n1NC(=O)c1ccc(Cl)cc1)CCCC2 +COc1ccc(N2CCOCC2)c2sc(NC(=O)C(C)(C)Oc3ccc4c(c3)OCO4)nc12 +COc1nc(N2CC(C)(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +COCCN1CCn2cc(C(=O)OC(C)C(C)(C)C)c(C)c2C1=O +Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(C3CCCN3)nc12 +N#Cc1ccc(C(c2cccnc2)N2CCC(NC(=O)c3c(F)cccc3F)CC2)cc1 +COc1cccc(CCCCCCCc2cccc(OC)[n+]2C)[n+]1C +c1cc(CN2CCCCC2)cc(OCCCN2CCC(Cc3c[nH]cn3)CC2)c1 +O=C(NCCCN1CCC2(CCc3ccccc32)CC1)C(=O)c1c[nH]c2ccccc12 +Cc1cc(C(N)(c2ccc3c(c2)c(-c2cccc(Cl)c2)cc(=O)n3C)c2cncn2C)ccc1Cl +CCB(CC)OC(=O)C(N)CCCCNC(=S)Nc1ccc(S(=O)(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +NCCCCC(N)CNC1CC(N)C2(CCC(O)C(O)CO2)C(O)C1O +Cc1c(C)c(C(C)C)n(CCC2CC(O)CC(=O)O2)c1-c1ccc(F)cc1 +CCn1c(C(O)c2ccccc2Cl)nc2cnc(Oc3c(F)cccc3F)nc21 +CN(C)C1CCCCC1N(C)C(=O)c1ccc(Cl)c(Cl)c1 +Cc1cc(-c2ccc(NC(=O)C(CC(C)C)c3cccc(-c4ccc(N5CCOCC5)cc4)c3)cc2)ccn1 +CS(=O)(=O)NC(=O)c1cccc2nc(C=Cc3nc4c(N5CCOCC5)cc(Cl)nn4c3-c3cccnc3)ccc12 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+CC(C)c1onc(COc2c(Cl)cc(Cl)cc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +CNS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2CCC(F)(F)CC2)cc1F +CS(=O)(=O)c1ccc(C(F)(F)F)cc1NC(=O)Nc1cnc(Oc2ccc(-c3cc(F)cnc3N)cc2)nc1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(c4ccccc4OC)CC3)c(OC(F)F)c21 +COc1ccc(S(=O)(=O)N(Cc2ccc3c(c2)C=CC(C)(C)O3)C2CCC2)cc1OC +COc1ccc(NC(=O)C2c3ccccc3C(=O)N(C3CCCC3)C2c2cccs2)cc1Cl +C=CCCC(=O)Nc1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +Cc1ccc(C(=O)NC(Cc2ccccc2)c2nc(-c3ccc4c(N)n[nH]c4c3)c(Cl)[nH]2)cc1 +COc1ccc2c(c1)OCCCCCCCCCN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +NS(=O)(=O)c1ccc(N2S(=O)(=O)c3ccccc3S2(=O)=O)c(Cl)c1 +COc1ccc2c(c1)CCC=C2CCCN1CCN(c2ccccc2OC)CC1 +COc1cc2c(cc1OC)-c1c(OC)c(O)c(Br)c3c1C(C2)N(C)CC3 +O=C(Cc1cccc(OC(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 +CC(NC(=O)c1cccc(-c2sccc2-c2cc(Cl)ccc2OCc2ccccc2)c1)c1cccnc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NCC3CCCO3)c2)[nH]1 +CCCc1cc(OC)cc2nc(-c3cccnc3N3CCN(C)CC3)oc(=O)c12 +COc1ccc(CC2(C(=O)OCc3ccccc3)CCCN2C(C)=O)cc1 +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-n1c(C)ccc1C +CCOc1cnc(OC)n2nc(NS(=O)(=O)c3c(Cl)cccc3Cl)nc12 +O=C1NCC2c3c(cccc31)CCN2C(=O)Cc1ccc(OCc2ccccc2)cc1 +OC(Cc1ccccc1)CN1CCN(CCSC(c2ccccc2)c2ccccc2)CC1 +CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(Cc1c[nH]c2ccccc12)NC(=O)C1CCCCN1 +C1=CC2(CCN(CCc3cccc4ccccc34)CC2)Oc2ccccc21 +O=S(=O)(Cc1ccccc1)N1CCN(c2ncccc2C(F)(F)F)CC1 +CC(C)(O)c1ccccc1-c1ccc2[nH]c(C=Cc3ccc(OC(F)(F)F)cc3)nc2c1 +CN1CCC(Nc2cccc(-c3nc4ccc(OCCCN5CCCC5)cc4o3)c2)CC1 +CC(=O)NCC(NC(=O)c1ccc(-c2nc(C3CCOCC3)cnc2N)cc1F)c1cc(F)cc(Br)c1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(-c3ccccc3)nc(-c3ccccc3)c2)CC1 +O=S(=O)(Nc1cccc(CO)c1)c1ccc(-c2ccc(F)cc2F)cc1 +O=C(NC1CNCCCC1OC(=O)c1cc(O)c(Cc2c(O)cccc2C(=O)O)c(O)c1)c1ccc(O)cc1 +CC(C)(C)N1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +O=C(Nc1cn(CC(=O)N2CC3CCCNC3C2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +COc1ccc2[nH]cc(C3CCN(CCCCn4c(=O)c(-c5ccccc5)c5ccccn5c4=O)CC3)c2c1 +CCC(C)N(C)C(=O)c1nc2ccccc2c(-c2ccccc2)c1CI +CCNc1ncc(-c2cn(-c3cc(C(=O)Nc4ccc(CN5CCN(C)CC5)c(C(F)(F)F)c4)ccc3C)nn2)cn1 +CC(C)OC(=O)C1=CN(C(=O)c2ccc(OCCN3CCN(C)CC3)cc2)CC(C)(C)c2c1[nH]c1ccccc21 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OCCF)c(C(=O)O)c2)c1 +O=c1[nH]c2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O +CCn1ccc(-c2cnc(C)nc2OCC2CC2c2ccc3ccccc3n2)cc1=O +COc1ccc(-c2csc(C(=O)NC3CCN(C(=O)OCc4cc(Cl)cc(Cl)c4)CC3)n2)cc1 +Brc1cccc(-c2[nH]ncc2-c2ccnc3ccccc23)n1 +C=CCC(C)(C(=O)NO)C(CC(C)C)C(=O)NC(CC1CCCCC1)C(=O)NCCc1ccc(S(N)(=O)=O)cc1 +COc1ccc(N(C)c2cnc(SCc3ccccc3)n2-c2ccc(F)cc2)cc1OC +O=C(CC1CC1)N1CCC(c2nc(-c3cccs3)no2)CC1 +CC(=O)Nc1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccccc2)sc2ccccc12 +CC(C)C(=O)NC1C(O)C=C(C(=O)O)OC1C(O)C(O)CO +O=C(c1cc2cc(O)ccc2[nH]1)c1cc2cc(O)ccc2o1 +CC1CN(c2sc(C(F)(F)F)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cnc2ccccc21 +O=C(CC1CCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1)NCCc1c[nH]nn1 +Nc1ccccc1NC(=O)c1ccc(C=CC(=O)NCCc2c[nH]c3ccccc23)cc1 +COc1cc(CNc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc(OC)c1 +O=S1(=O)CCC(CNC2CCC(Nc3cc(-c4ccc(F)c(NCC5CCOCC5)n4)c(Cl)cn3)CC2)CC1 +CSc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C)n1 +CCS(=O)(=O)N1CC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CC(C)(N)C(=O)N1CCn2c(nc(-c3ccc(F)cc3)c2Nc2ccc(F)c(F)c2)C1 +COc1ccc(CNC(=O)CCCCCCCC(=O)NCc2ccc(OC)c(O)c2)cc1O +O=c1ccc(-c2ccc(OC3CCN(C4CCCC4)CC3)nc2)n[nH]1 +Cc1nc2c(c(-c3ccc(Cl)cc3Cl)c1CN)C(=O)N(CC(=O)N1CCCC1)C2 +O=C(Nc1ccc(-c2ccc(C(=O)C3CCCC3C(=O)O)cc2)cc1)Nc1cccc(C(F)(F)F)c1 +CCOC(=O)N1CCN(CC2CCCN2S(=O)(=O)c2ccc3c(c2)C(=O)C2=NCC(C)(C)CN23)CC1 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2(O)CCCNC(=O)CI +Cc1ccc(C(=O)Nc2sc(Nc3ccc4cc(CO)ccc4c3)nc2C(N)=O)s1 +Cc1cc(Nc2nc(NC(C)c3ccc(F)cn3)c(F)c(N3CCN(S(C)(=O)=O)CC3)n2)n[nH]1 +Cn1nc(NC(=O)Cc2ccccc2)c(-c2ccncc2)c1-c1ccc(F)cc1 +O=C(NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O)c1ccc2c(c1)nc(-c1cccs1)n2C1CCCCC1 +COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1NC(=O)NC(C)c1nccs1 +Cc1ccc(C)c2nc3c(C(=O)NCCCN(C)CCCNC(=O)c4cccc5cc6c(C)ccc(C)c6nc45)cccc3cc12 +CC(=O)c1cc2c(o1)C(=O)c1c(O)cccc1C2=O +CN(C)CCNC(=O)c1cccc(NC(=O)Nc2ccc(N(CCCl)CCCl)cc2)c1 +CC(O)CCc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O +CC(C)Sc1ccc(CC2CCN(C3CCN(C(=O)c4cccc5cc(F)ccc45)CC3)CC2)cc1 +Cc1cc(CNC(=S)CCc2ccc(C(C)(C)C)cc2)ccc1NS(C)(=O)=O +COc1ccc2c(=O)cc(C=Cc3ccc(O)c(O)c3)oc2c1OC +O=C(C=Cc1noc(-c2cc(Cl)c(O)cc2O)c1-c1ccc(O)cc1)N1CCN(c2ncccn2)CC1 +NC(=O)c1c(NC(=O)c2ccc(OCc3ccccc3)cc2)sc2c1CCN(C(=O)c1ccccc1)C2 +O=C(NO)C1CC(O)CCN1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1 +Nc1cccc2cc3c(=O)[nH][nH]c(=O)c3cc12 +COc1ccc(Nc2ncc3c(n2)-c2ccc(F)cc2NC(=O)C3)cc1OC +CN(C)CC(Cc1ccccc1)c1cccc(OCCNS(=O)(=O)c2cnn(C)c2)c1 +O=C(OCCCc1ccc(F)cc1)C1CCCCN1S(=O)(=O)Cc1ccccc1 +CCn1nnc(C2OC(n3cnc4c(NC5CC6CCC5C6)ncnc43)C(O)C2O)n1 +CC(CO)NS(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1 +CN(C)CCSc1nc(N)nc(-c2c(Cl)cc3c4c(cccc24)COC3)n1 +CCNc1c2c(nc(NC(=O)Nc3ccc(OC)cc3)n3nc(-c4ccco4)nc23)nn1C +Cc1cccc2scc(Cn3c(SCCCC(=O)O)nc4ccccc43)c12 +O=C1c2ccccc2C(=O)N1CC=CCN1CCN(Cc2ccc(Cl)cc2)CC1 +COc1cc2ncnc(N3CCN(C(=NCc4ccc(Cl)cc4)NC#N)CC3)c2cc1OC +O=C(Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cn1)c1ccccc1Cl +CCN(CC)Cc1cc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)c2ccccc2)ccc1O +CN(C)c1ccc(-c2cn(-c3ccc(OCCOCCOCCO)cc3)nn2)cc1 +Nc1nc2c(ncn2C2CC(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1 +COC(=O)C(C)NP(=O)(OCC1OC(C)(C)OC1C(=O)NO)Oc1cccc(C)c1C +NC1CCN(c2cncc(-c3n[nH]c4ccc(-c5c(F)cccc5F)cc34)n2)C1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(OCC)cc(-c3ccccc3)n2)CC1 +Cc1ccc(NC(=O)c2ccnc(S(C)(=O)=O)c2)cc1-c1ccnc(N2CCOCC2)c1 +COc1cc(N)c(Cl)cc1C(=O)OC1CC2CCC1CN2C +O=C(CCCCCNC(=O)Nc1cccc(-c2nc3ccc(F)cc3o2)c1)NO +Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3[nH]nnc3n2)c(OC(C)C)cc1C1CCN(C)CC1 +COc1ccc(C(=N)NCCCCCCCCCCCCNC(=N)c2ccc(OC)c(OC)c2)cc1OC +c1ccc(CN2CCCC(n3cnc4cnc5[nH]ccc5c43)C2)cc1 +CC(=O)NC1CCN(c2ccc3c(C=O)c(O)ccc3n2)C1 +CN(c1ccc2c(c1)C(=NNC(=N)N)CC2)S(=O)(=O)c1c(Cl)nc2sccn12 +O=C(c1cccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)c1)N1CCOCC1 +COc1cc(Cl)c(C=NNC(=O)CSc2cc(C)nc3ccccc23)cc1OC +CC1(C)C=Cc2c(ccc(-c3coc4cc(O)ccc4c3=O)c2O)O1 +[C-]#[N+]c1ccc(CCc2ccc3c(-c4ccc(OC)cc4F)cc(C(N)=O)nc3c2)cn1 +CC(C)(O)c1cc(-c2ccc(S(N)(=O)=O)cc2)c(-c2ccc(F)cc2)s1 +CCC(CO)Nc1nc(NCc2ccc(-c3ccccn3)cc2)c2[nH]nc(C(C)C)c2n1 +Cc1cncc(-c2cc3c(cnn3-c3cccc(N4CCNCC4)n3)nn2)n1 +CCCN1CCc2cc(OCCF)cc3c2C1Cc1cccc(O)c1-3 +COCC1CCCN1c1cc(NC(C)=O)nc(-c2ccc(C)o2)n1 +COc1ccc(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(OCCN4CCCCC4)cc3)n2)c(OC)c1 +O=C(NCc1nc2ccccc2c(=O)n1-c1ccc(F)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)NCc5c(Cl)cccc5C(F)(F)F)cn4c3)cc2)CC1 +CC(C)NC(=O)N(Cc1cccc(C#Cc2ccncc2)c1)Cc1cccc(C#Cc2ccc(Cl)cc2)c1 +Nc1[nH]c2cc([N+](=O)[O-])ccc2c1-c1ccccn1 +CCc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 +COC(=O)C(NC(=O)NC(C(=O)NC1CCCCNC(=O)C=CC(Cc2cccc(F)c2)NC1=O)C(C)C)C(C)C +O=C(c1ccc(Cl)c(Cl)c1)N1CCC(CNCCc2cccnc2)CC1 +N#Cc1c(Cl)cc(Cl)cc1-c1cccc(C(=O)CC(=O)C(=O)O)c1 +COc1nc2c(cc1C(=O)N1CCn3c(cnc3-c3ccc(F)cc3F)C1)c(C(=O)C(=O)N1CCC(O)C1)cn2C +NCCc1c[nH]c2ccc(OCC(=O)N3CCN(c4ccc(CN)cc4)CC3)cc12 +Cc1nc(C#Cc2cncc(-c3ccc(CO)cc3)c2)cs1 +O=C(NCCC1CCN(CC2COc3ccccc3O2)CC1)Oc1ccccc1 +O=C(Nc1ccc(C(=O)N2CC3COCCN3Cc3ccccc32)c(Cl)c1)c1cc(F)ccc1-c1ccccc1 +Nc1nc(N)c(NC(=O)Nc2ccc(C(=O)NC(CCCC(=O)O)C(=O)O)cc2)c(=O)[nH]1 +CCNC(=O)Nc1nc2cc(-c3cccnc3)c(=O)n(C(C)C(N)=O)c2s1 +Cc1ccc(C(=O)Nc2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cnc(N(C)CCN(C)C)nc12 +Cc1cc(NS(=O)(=O)C(C)(C)C)ccc1-c1c(C(N)=O)c2cc(F)c(OC(F)F)cc2n1-c1ccccc1 +CC1C2c3cc(O)ccc3CC(c3ccc(O)cc32)N1C +CS(=O)(=O)OCc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1 +CCNC(=O)C1OC(n2cnc3c(N(C)C)ncnc32)C(O)C1O +O=C(CCCN1CCC(CO)(c2ccc(Cl)cc2)C1)c1ccc(F)cc1 +COc1cccc(-c2ccc3c(c2)C2(COC(N)=N2)C2(COC2)C(C)(C)O3)c1 +NC(CC(CCC(=O)NOCc1ccccc1)C(=O)O)C(=O)O +Cc1cc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cnc1F +O=C(NCC1CC1CN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2ccccc2[nH]1 +COC1(C)CCC(Oc2n[nH]c3cc(NC(=O)NC(COC(F)F)c4ccccc4)ncc23)CC1 +CCNC(=O)Nc1cn2c(-c3nc(C)cc(C(F)(F)F)n3)cc(-c3cccnc3)cc2n1 +COc1cccc2sc(C3CCN(CC(O)COc4cccc5[nH]ccc45)CC3)cc12 +CC(C)C(NC(=O)C1CCOCC1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)C(F)(F)F)C(C)C 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+CC(C)(NC(=O)c1cccc(-c2cccc(Cl)c2)n1)c1ncco1 +CC(C)NS(=O)(=O)c1ccc(-c2ccc3c(cnn3-c3ccc(F)cc3)c2)c(C(F)(F)F)c1 +CN1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(F)c3Cl)c2O)CC1 +OC1CCC(c2cccnc2Oc2ccc(Nc3nc4ccccc4s3)cc2)CC1 +c1cc2[nH]cc(-c3cncc(C4CC4)n3)c2cc1-c1nnc(NC2CC2)o1 +Nc1cccc2ccc(-n3c(-c4ccnc(NC5CCOCC5)c4)n[nH]c3=O)cc12 +O=C(C=Cc1ccc(CNCCc2c(-c3ccccc3)nn3ccccc23)cc1)NO +CN(C)CC(=O)NC(c1ccc(Cl)cc1)c1nc2ccc(-c3cn[nH]c3)cc2c(=O)[nH]1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(C)ccc3nc2-1 +O=C(Nc1csc(-c2nncn2C2CC2)n1)c1cc(-n2cnc(C3CC3)c2)c(N2CC3(CCOCC3)C2)cn1 +CCOC(=O)c1cn(-c2ccc3c(c2)CCC3)c2nc(Nc3ccc(N4CCN(C)CC4)cc3)ncc2c1=O +Cn1c(SCCCN2CC3CCN(c4ccc(F)cc4C(F)(F)F)C3C2)nnc1-c1cnccn1 +N=C(N)NCCCC1CC(OCc2ccc3ccccc3c2)CN1C(=O)C(Cc1ccccc1)NC(=O)C1Cc2ccccc2CN1 +CCOC(=O)c1c(-c2ccc3c(c2)OCO3)[nH]c2cc(OC)c(Cl)cc2c1=O +Cc1cc(Cl)c(NC(=O)N(Cc2ccc(Oc3ccc(F)cc3)cc2)C2CCCCCC2)c(Cl)n1 +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2nc(CN3CCC(c4ccc(F)cc4)CC3)ccc2c1 +O=C(N1CCN(Cc2ccc([N+](=O)[O-])cc2)CC1)n1nnc2ccccc21 +NC(=O)CCc1c(-c2ccccc2)c(O)nc2cc(Cl)ccc12 +COc1ccc(F)cc1CNCCCNc1ccnc2cc(Cc3ccc(C#N)cc3)ccc12 +COc1cc(C=CC(=O)NCCn2c(C(F)(F)F)cc3ccccc32)cc(OC)c1OC +CCCCOC1Oc2ccccc2C(=O)C1=CNc1cccc(S(N)(=O)=O)c1 +CCN(CC)CCCNc1nc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2o1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1Oc1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 +CC1(C)Oc2cc(C34CC5CC(CC(N=C=S)(C5)C3)C4)cc(O)c2C2CC(O)CCC21 +CS(=O)(=O)N1CCc2c(c(-c3ccc(Br)cc3)nn2CC(O)CN2CCC(N3CCCc4ccccc43)CC2)C1 +O=c1ccc2cnc3ccc(-c4cnc5[nH]ccc5c4)cc3c2n1-c1ccc(F)c(C(F)(F)F)c1 +Cc1ccc(C(=O)Nc2cc(-c3c(-c4ccc(F)cc4)nc4n3CCS4)ccn2)cc1F +CSc1nn2cc(-c3nc4c(C)cc(Cl)cc4s3)nc2s1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NC(=O)c4cccc(OC(F)(F)F)c4)nc23)N1 +CCOC(=O)NC1N=C(c2ccccc2)c2ccccc2-n2c(C)nnc21 +COc1cc(N2CCN(C3CCN(c4cccc5c(C)cc(C)nc45)CC3)CC2)c2ncccc2c1 +Oc1ccc(-c2nn(Cc3ccccc3)c3c(Cl)cccc23)cc1 +COc1cc[nH]c1C=C1C(=O)Nc2ccc([N+](=O)[O-])c(N3CCC(N)CC3)c21 +CCCN1CCC2(CC1)Oc1ccccc1C1CC(c3ccc(F)cc3)=NN12 +CC(COC(=S)Nc1ccc(Cl)cc1)NC(=O)c1ccccc1C(=O)O +COc1cc(-c2cc(F)c(F)cc2F)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +COc1ccc(COc2ccc3c(Cn4ccnc4)cc(=O)oc3c2)cc1 +CCCN(CCC)c1cccc2nc(Nc3c(OC)cc(COC)cc3OC)c(C)cc12 +O=C(OCCCCN1CCN(CCO)CC1)c1cc(O)c2c(c1)C(=O)c1cccc(O)c1C2=O +O=C(NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)NC(Cc1ccncc1)C(=O)O +COc1cccc(N2CCN(CCN3CCCCCC3)C2=O)c1 +C=Cc1cccc2c1N1CCCC(NC(=O)C(F)(F)F)C1c1ccccc1O2 +CN(C(=O)c1ccc(NC(=O)Cc2ccc(NC(=O)C3CCN(C(=O)c4ccccc4)CC3)cc2)cc1)C1CC1 +Cc1nc2c(o1)CN(C1COC(c3cc(F)ccc3F)C(N)C1)C2 +COc1cc(C(O)P(=O)(O)CCC(N)C(=O)O)ccc1OCC(=O)O +O=c1cc(CSc2nnc(-c3cccs3)n2Cc2ccccc2)nc2sc3ccccc3n12 +CCN(Cc1ccccc1)Cc1ccc(C=CC(=O)NO)o1 +O=C(CCN1CCOCC1)Nc1ccc(-c2cccn3c(=O)cc(N4CCOCC4)nc23)c2oc3ccccc3c12 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2cc(-c3ccc(C(=O)O)cc3)ccc2c1 +COc1ccc(-c2ccc3nccc(Nc4cccc5[nH]ncc45)c3c2)cc1F +COc1ncnc(Cn2cc(C(=O)NCCF)c3ncc(C(F)(F)F)cc32)c1C +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)CC1CCCNC1)C2 +Cc1cc(NC2CCN(CCC(=O)O)CC2)nc(NCc2cn(CCCNCCCNC3CCCCC3)nn2)n1 +CC1=CCCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2(C)CCCOC2)c1O +COc1ccc(-c2cccc(CN3CCN(c4ncccn4)CC3)c2)cc1 +CCN(CC)CCCC(C)N=c1cc(C=Cc2ccccc2Cl)[nH]c2cc(Cl)ccc12 +Cc1cc(C)nc(N=C(N)Nc2ccc(S(=O)(=O)O)cc2)n1 +CC(C)n1cnc2c(Nc3ccc(-c4ccccc4)cc3)nc(NC(C)(C)CO)nc21 +Clc1ccc(CN2CCC3(CCCc4ccccc43)CC2)cc1 +O=C(O)C1Cc2cc(-c3ccccc3)ccc2CN1C(=O)C(c1ccccc1)c1ccccc1 +CCC(=O)N(Cc1cccc(C)c1)C1CCN(CCc2ccccc2)CC1 +Cc1ccc(NC2CCCN(C(=O)c3ccccc3-n3nccn3)C2C)nc1 +Cc1cccc(Cl)c1-c1ccc(N2CCOc3ncnc(N)c3C2=O)cc1 +Cc1cccn2cc(-c3ccc(OCCCN4CCCCC4)cc3)nc12 +CCOP(=O)(CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(C)c3ccccc3)c2)[nH]1)OCC +CC(NC(=O)Nc1cc2[nH]nc(NCc3ccncc3)c2cn1)c1ccccc1 +CC(C)(C)C(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +O=C(CCCCc1ccc2c(n1)NCCC2)NCC(C(=O)O)c1ccccc1 +COc1cc(C(C)NC(=O)Nc2cc3[nH]nc(OC)c3c(CO)n2)ccc1Cl +C=C1C(=O)C23CC1CC(O)C2C12CCCC(C)(COC(C)=O)C1C(O)C3(O)OC2 +O=C(Nc1ccc(F)cc1)c1cc(O)c2cccc(O)c2n1 +CCN(Cc1ccc(C#CCCO)cc1)CC1CCCN(CCc2cccc(F)c2)C1 +N=C(N)c1ccc(N2CCC(N3CCN(CC(=O)O)CC3)CC2)cc1 +CCC(Nc1ccc(Cl)c(CN2CCC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 +C=Cc1cccc2nc3c(cc12)Cn1c-3cc2c(c1=O)COC(=O)C2(O)CC +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1-n1cccn1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1cccc(N(C)C)c1 +O=C(Nc1ccc(F)cc1)N1CC2CCN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1 +Cc1ncc(C)n2nc(CCc3nc(-c4ccoc4)cn3C)nc12 +Cc1cc(SCC=CC(C#Cc2ccccc2)c2ccc(Br)cc2)ccc1OCC(=O)O +CC(O)C(C)Nc1nc(Nc2ccc([S+](N)[O-])cc2)ncc1Br +O=C(O)CSc1cc(NS(=O)(=O)c2ccc(Br)cc2)c2ccccc2c1O +CN1C(=O)C(NC(=O)Nc2cccc(N(C)c3nn[nH]n3)c2)N=C(c2ccccc2)c2ccccc21 +CCC(CS(=O)(=O)C(C)(C)C)N1C(=O)C(C)(CC(=O)CO)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +NC(=O)C(N)CCC(=O)Nc1ccc(Cc2ccccc2)cc1 +Nn1c(SCc2ccc(F)cc2)nnc1-c1c[nH]c2ccccc12 +CC(C)(O)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CCOC(=S)SCCCCCC=C(NC(=O)C1CC1(C)C)C(=O)O +CC(NC(=O)C(NC(=O)CCc1ccccc1)C(C)C)C(=O)NC(CC(=O)O)C(=O)CCCCc1ccccc1 +O=C1Nc2cc(-c3ccc(O)cc3)ccc2C1=Cc1ccc[se]1 +COc1cnc(N2CCN(C(=O)Cn3cc(-c4ccc(F)c(C)c4)nc3-c3ccccc3)CC2)nc1 +CN(C)C(=O)C(=O)N(C)C(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +CNc1nc2[nH]c(-c3cccc(CNC(=O)CCN(C)C)n3)cc2c2c1ncn2C +CC(C)(C)n1cc2c(n1)C(=O)CC1(CCN(C(=O)c3ccc4[nH]ncc4c3)CC1)O2 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCC2CCC3CC2C3(C)C)cc1F +O=C(CCCCCCCn1cc(-c2ccc(-c3ccncc3)cc2)nn1)NO +Nc1cc(C2CCCNC2)nc2c(-c3cccc(O)c3)cnn12 +COc1ccc(C(CCCCCCc2ccc3c(n2)NCCC3)CC(=O)O)cn1 +OC(CCN1CCN(c2ccc(Cl)cc2)CC1)c1cccs1 +COCC1CCN(C(CCc2ccccc2)C(=O)NC(Cc2cc(F)cc(F)c2)C(O)CNCc2cccc(OC)c2)C1=O +CCOc1ccc2ccccc2c1-c1cc2nc(N)nc(N)c2cc1C +COc1ccc2c(c1)c(=O)c1c(NCCN(C)C)ccc3ncn2c31 +O=C(O)c1cc(S(=O)(=O)Nc2ccc(Br)cc2Br)c2ccccc2c1O +O=C(CCN1CCCC1)NC1CCC(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +O=C(Nc1ccc2sc(-c3cccc(F)c3)nc2c1)N1CCCCC1 +CCCn1cc(-c2cnc3ccc(NC(=O)NC(C)CCCc4ccccc4)nc3n2)cn1 +CCOc1ccc(Cc2nc3cc(SCC)c(Cl)cc3n2CC2CCOCC2)cc1 +Cc1cnc(Nc2ccc(C#N)cc2)nc1Cc1c(F)cccc1F +CCCC(=O)NCCCc1cccc2nc(-c3ccccc3)oc12 +CCN(CC)CCOc1ccc(Nc2cc(N(C)C(=O)Nc3c(Cl)cccc3Cl)ncn2)cc1 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+O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)ccc2n1CCC(=O)n1ccnc1 +CCC(OC)(c1cc(F)cc(OCc2ccc3c(ccc(=O)n3C)c2)c1)c1nccs1 +OC1(c2ccc(Cl)cc2)CCN(Cc2c[nH]c3ccccc23)CC1 +CC(C)c1n[nH]c2c(NCc3ccc(-c4ccccn4)cc3)ncnc12 +CC(=O)Nc1cccc(C2CCN(CCCn3nc(-c4ccc(Cl)cc4)c4ccccc4c3=O)CC2)c1 +CCc1nc(N)nc(N)c1C#CCc1cc(OC)ccc1OC +O=C1NC2CCc3cccc(c32)-c2c1[nH]c1ccccc21 +Cc1cc(-c2nnc3n2CC(C)N(Cc2cccc(C(F)(F)F)c2Cl)C3=O)n[nH]1 +O=C(Nc1ccc(C2CCCNC2)cn1)c1ccc(Cl)cc1 +CCCSC(=O)N1CC(C(C)OC(=O)CCCc2ccccc2)C1=O +COc1ncc(-n2nc(C)c3c2C(=O)N(c2cc(C)c(=O)n(C)c2)C3c2ccc(Cl)cc2)c(OC)n1 +CC(C)(C)c1ccc(C(=O)Nc2cn3cc(-c4ccccc4)ccc3n2)cc1 +O=C(Nc1cccc2[nH]ncc12)NC1CCC(c2ccc(C(F)(F)F)cc2)C1 +O=C(N1CCOCC1)N1CCN(c2ccc(Cl)cc2)CC1 +CC1(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2F)CS(=O)(=O)C2(CCCCC2)C(=N)N1 +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CC2(CC(O)CO2)C1 +CC(=O)c1cccc(CN(Cc2ccc(C(F)(F)P(=O)(O)O)cc2)S(=O)(=O)c2ccc(OCC(=O)O)cc2)c1 +CSc1ccc(C2CN(C)Cc3cc(Oc4ccnc(CN5CCCCC5)c4)ccc32)cc1 +COc1nc(N2CC(F)(F)C2)nc(OC)c1NC(=O)CC(C)(C)C 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+CCCCN1CCC(CNC(=O)c2c3n(c4ccccc24)CCCO3)CC1 +CC(C)Oc1cc2c(cc1NC(=O)c1ccncc1)n(C)c(=O)n2C +CC1COCCN1c1cc(CS(C)(=O)=O)nc(-c2ccc(NC(=O)NC3CC3)cc2)n1 +CC(c1nc2ccc(N3CCCC(C(=O)N4CCCC4)C3)nc2[nH]1)n1cc(Cl)cn1 +Nc1cnc(-c2ccc(C3CCC3)c(Oc3ncc(C(F)(F)F)cn3)c2F)cn1 +Cc1cc(Oc2ncc(Cl)cc2Cl)ccc1-c1c(C)c(=O)[nH]c(=O)n1C +N=C(N)c1csc(CNC(=O)C2CCCN2C(=O)C(NS(N)(=O)=O)C(c2ccccc2)c2ccccc2)c1 +O=C(c1ccc(C(=O)N2CCC(N3CCCC3)CC2)cc1)N1CCCC(N2CCCC2)CC1 +CC(C)Oc1ccc(NC(=O)C2CC3CCC2N(S(=O)(=O)c2ccccc2F)C3)cc1 +CCCN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCC1 +CC1(O)CCC(Nc2c(C(N)=O)cnn3cc(-c4cncnc4N)cc23)CC1 +CCCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C1CCCC1)CC2 +O=C(Nc1nc(CF)cs1)c1cc(Cl)cc(Oc2cncnc2)c1 +Cc1c(C(=O)NCCCN2CCOCC2)sc2ncnc(Nc3cccnc3OC(C)C)c12 +CCOC(=O)c1nn(C(=O)c2ccccc2)c2ccc(OC(F)(F)F)cc12 +CCOc1csc(-c2ccc(OCCCOc3ccc4c(c3)CCC4CC(=O)O)cc2)n1 +CC(Cc1ccccc1)(NC(=O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)N1CCC2(CCCC2)CC1)C(=O)O +CCCn1cc(-c2cccc(-c3cnc(N)c(C(=O)NC4C5CC6CC4CC(O)(C6)C5)n3)c2)cn1 +COc1ccc(C2c3nc(CCC(=O)O)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)cc1 +CCCCc1nc(CCCC)n(Cc2ccc(-c3ccccc3-c3nn[nH]n3)nc2)n1 +Cc1cn(C2CCCCC2)c2cc(C(=O)Nc3c(Cl)c[n+]([O-])cc3Cl)ccc12 +Cc1nc(C(C)N(Cc2ccccc2Cl)c2ccc(C#N)c(Cl)c2)cs1 +CCCC(CNC(CNC)Cc1ccc(O)cc1)NCC1CCCCCC1 +Cc1sc(-c2cc(F)cc(F)c2)nc1CSc1nc(N)cc(N)n1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2ccccc2F)cc1 +Cc1nn(C(C)(C)C)cc1-c1cc(Cl)ccc1Oc1cc(F)c(S(=O)(=O)Nc2nncs2)cc1Cl +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(CC(=O)NO)c1ccccc1 +CC(C)N1CCCC(n2cc(S(=O)(=O)c3ccc(Cl)cc3)c3cccnc32)C1 +CCCCC(C=NNC(=O)SC(C)C)NC(=O)OC(C)(C)C +CC(C)c1cc(C(C)C)c(S(=O)(=O)NC(Cc2cccc(C(=N)N)c2)C(=O)N2CCOCC2)c(C(C)C)c1 +Cc1ccc(Oc2ccc3c(c2)CC(NCC(O)c2cccc(Cl)c2)CC3)cc1C(=O)O +COc1cccc(C23CCN(C)C(C2)C(=Cc2ccccc2)C(=O)C3)c1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1cnc(C#N)c(Cl)c1 +CC1(C)CC(C)(C)CC2(C1)OOC1(CC(C)(C)CC(C)(C)C1)OO2 +O=C(Nc1nc2cc(C(F)(F)F)cc(NC3CC3)n2n1)c1cccnc1 +CCCOCCn1c(=O)c(NCCO)nc2cnc(-c3ccc(OC)nc3)cc21 +CN(C)CCn1cnnc1-c1cc(Oc2ccc(NC(=O)NN=Cc3ccc(Cl)cc3Cl)cc2F)ccn1 +CC1(C)C2CC=C(C[N+](C)(C)Cc3ccc(-c4cccc(Cl)c4Cl)cc3)C1C2 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4cnc(-c5ccncc5)s4)s3)c2)C(O)C(O)C1O +CNCCn1cc(-c2ccc(F)c(C)c2)nc1C1CCN(c2ncnc(N)c2C(N)=O)CC1 +Cc1cc(-c2ccc(C(=O)c3cccc(O)c3)nc2)ccc1O +CCN1CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)CC1=O +CC1Cc2c(ccc(C3CN4CCN(C(=O)C5CCc6nc(-n7cnnn7)ccc65)CC4CO3)c2F)C(=O)O1 +O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2oc(-c3ccccc3)cc21 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cc(C(F)(F)F)ccc1NC(=O)N1CCC1 +CCOC(=O)c1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3cccnc3)c2c1 +CNC(=O)c1ccc(F)c(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1 +COc1cc(Nc2nc3cccc(-c4cccc5[nH]cnc45)c3o2)cc(OC)c1OC +CC(C)(NC(=O)Nc1nc(-c2ccncc2)cs1)c1ccccc1 +CC(C)Oc1cccc2c1C(=O)N(COC(=O)c1c(Cl)cccc1Cl)S2(=O)=O +CC(C=CC=C(C)c1cc(C(C)C)cc(C(C)C)c1OCC(F)(F)F)=CC(=O)O +Cc1nc2cc(F)ccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2ccccc2)CC1 +Cn1cc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)c(F)c2)cn1 +O=C(C=CCN1CCCCC1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1 +CCN(CC)c1ccc(CN2CC(C)C(c3nn4c(C5CCOCC5)ncc4c(=O)[nH]3)C2)cc1 +O=C(O)CCn1cc(Cn2ccnc2)c2ccc(C(F)(F)F)cc21 +CN1CCc2cc(Cl)c(O)cc2C2c3ccc(N)cc3CCC21 +CC1=C(c2ccc(O)cc2)C(=O)c2cc(O)ccc21 +O=C(c1nnc(-c2ccccc2)o1)N1CC(Oc2ccc(CN3CCCC34CCOC4)cc2)C1 +Cc1cccc(COC(=O)N2CCc3ncsc3C2c2cc(Cl)ccc2OCC(=O)O)c1C +COc1cc(-c2cc3ncccc3c(NCC3CC(=O)NC3C)n2)cc(OC)c1OC +O=C(Nc1ccc(-n2ccnc2)cc1)C1=C(O)CC(Cc2ccccc2)NC1=O +COc1ccc(S(=O)(=O)NCCCCc2cc(C(=O)O)c3ccc(C(C)C)ccc2-3)cc1 +COCCOc1ccc(Nc2c(C)c(NC3CCCNC3)nc3ccnn23)cc1 +CCNC(=O)C1OC(n2cnc3c(NC(=O)Nc4cccc(Cl)c4)ncnc32)C(O)C1O +O=C(NC1CCCCC1NCc1ccc(Cl)c(Cl)c1)c1ccc2ccccc2c1 +CCCc1nn(C)c2c(O)nc(-c3cc(S(=O)(=O)N4CCN(C(N)=O)CC4)ccc3OCC)nc12 +Cc1c(-c2ccc(=O)n(Cc3ccc(F)cc3F)n2)c2cc(F)ccc2n1CC(=O)O +CC1(C)CC(N2CCN(C(c3ccccc3)c3ccccc3)CC2)=CC(=[N+]2CCCCC2)C1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4ccccn4)ccn23)c1 +CC(C)Oc1ccc(-c2nc(-c3ccc4[nH]c5c(c4c3)CCC5CC(=O)O)no2)cc1C#N +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3c(C)ccc4[nH]nc(C)c34)nc(OCCN3CCOCC3)c2C1 +COc1cc2[nH]c(C)c(-c3ccc(C(F)(F)F)cc3F)c(=O)c2cc1Cl +CCCOC(=O)NCc1nc(-c2nc(C)cs2)c(-c2ccc3ncsc3c2)[nH]1 +CC1(C)Oc2nc([N+](=O)[O-])cn2CC1OCc1ccc(OC(F)(F)F)cc1 +CC(C)(C)OC(=O)NCCNC(=O)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 +N#CCCNCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +Cc1cn(C2CC(O)C(COP(=O)(O)CP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]c1=O +O=C1CC(=O)CC(c2cc(-c3ccccc3)cc(C(F)(F)F)c2)C1 +CC1Cn2c(nnc2-c2ccc(F)cn2)C(=O)N1Cc1cccc(C(F)(F)F)c1Cl +CCOc1ccc(-n2nc3c(N4CCC(OC)C4)nnc(C)c3c2C)cc1 +C=CC(=O)N1CCCc2[nH]c3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn3c2C1 +Cc1c(C#N)cc2nc(O)c(O)nc2c1[N+](=O)[O-] +COc1ccc(C(=O)Nc2c(F)cncc2F)c2ccc(C(F)(F)F)nc12 +CCNC(=O)CN1CCCC(NC(=O)c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)C1 +Cc1cc(-c2nnc(N)nc2-c2ccccc2)cc(C)c1O +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCc2c(Cl)ccc3c2C(CCC3)C1 +CCCc1nc(-n2cccc2C(=O)O)c(C#N)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(C)(O)c1ccc(C(O)CCCN2CCC(C(O)(c3ccccc3)c3ccccc3)CC2)cc1 +CC(=O)SC1CC(COCc2cc(F)c(F)cc2F)N(C(=O)Oc2cccc3c2OCCO3)C1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccc(O)cc3)[nH]c2c1 +CC(CO)Oc1cc(Oc2ccc(C(=O)N3CCC3)cc2)cc(C(=O)Nc2nccs2)c1 +CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C#N)cc3)c2)CC1 +CCCCC1Nc2ccc(CC)cc2C(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cn1c2c(c3cc(S(=O)(=O)c4ccc(C#N)cc4)ccc31)C1CCC(C2)N1 +O=c1[nH]cnc2c(CNC(CO)CC(F)(F)P(=O)(O)O)c[nH]c12 +O=c1[nH]c2ccc(Br)cc2c(C=Cc2ccccn2)c1-c1cccs1 +COc1ccc(C2Cc3c(cccc3C(F)(F)F)N(CCN(C)C)C(=O)C2C)cc1 +CNc1nc(NC)nc(NCCc2ccc(S(N)(=O)=O)cc2)n1 +NCC1CCn2cc(c3ccccc32)C2=C(C(=O)NC2=O)c2cn(c3ccccc23)CCO1 +CCCC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CC)nc3c(C)cc(C)nc32)cc1 +CCOc1cc2cc(CO)c(CO)c(C3=CCN(CCOC)C(=O)C3)c2cc1OC +Cc1ccc(C(=O)N2CCC2c2nnc(-c3ccccc3OC(F)(F)F)[nH]2)c(-n2nccn2)c1 +Cc1cc(F)ccc1Oc1cc(Cl)c(Cl)cc1C(=O)Nc1ccc(C(=O)O)cc1 +O=C(c1c(O)ccc2cccnc12)N1C2CCC1C(COc1ccccn1)C2 +O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1Cc1ccc(OCc2ccccc2Cl)cc1 +CCOC(=O)c1[nH]cc2nc3ccc(OCc4ccc5ccccc5c4)cc3c-2c1CC +COc1nc(N)c(Cl)cc1C(=O)NC1CC2CCCC(C1)N2C +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccccc1 +CNC1=Nc2ccc(N(C)Cc3ccnnc3)c3cccc1c23 +O=C(O)c1csc(-n2nc(-c3cccc(-c4ccccc4)c3)cc2O)n1 +CCCCC#Cc1nc(NC)c2ncn(C3C(O)C(O)C4CC43)c2n1 +CCCn1c(=O)c2[nH]c(-c3ccc[nH]3)nc2n(CCCOC)c1=O +CCCCN1C(=O)C(=CNCC2CCC2)C(=O)c2cccc(C)c21 +O=C(NCc1cc(F)ccc1F)Nc1ccc(S(=O)(=O)N2CCC(CNCC(O)COc3ccc(O)cc3)CC2)cc1 +CCOC(=O)C1=C(Nc2ccc(F)cc2)CC(c2ccc(Cl)cc2)N(c2ccc(F)cc2)C1c1ccc(Cl)cc1 +O=C(O)Cc1csc(NC(=O)c2nc3ccccc3n(C3CC4CCC(C3)N4C3CCCCCCC3)c2=O)n1 +COc1ccc(C(=O)Nc2ccccc2C(=O)NN=Cc2ccccn2)cc1OC +CC(Sc1cc(-c2ccc(C(=O)N(C)C)cc2)cnc1N)c1c(Cl)ccc(F)c1Cl +CC(C)Oc1ccc(N=c2[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +CC(=O)c1ccc2c(c1)C(NC(=O)c1ccsc1Cl)C(O)C(C)(C)O2 +O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CN(C2CCC(O)(c3cncs3)CC2)C1 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2CC(=O)NCC2CCOCC2)cc1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1-n1cc(-c2cncc(NC(C)(C)C)c2)nn1 +Oc1cc(C2=NCCN2)ccc1-c1cn(-c2cccc(C3=NCCN3)c2)nn1 +COc1ccc(N(C)c2nc(C)nc3c2C(C)CC3)cc1 +O=c1[nH]nc2c(NCCCc3cccnc3)cc(Cl)cn12 +CCc1c(C)sc2c1C(N1CCN(C)CC1)=Nc1cc(F)ccc1N2 +COC(=O)CN1CCCCC(NC(=O)C(CC(=O)NO)CC(C)C)C1=O +O=C(Nc1nn[nH]n1)c1cnc(N2CCOCC2)nc1OC1CCCCCC1 +CCN=CC1=Cc2c(cc3c(c2OC)OCO3)C(c2cc(OC)c(OC)c(OC)c2)C1C(=O)OC +CN1CCN(Cc2c(Oc3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)ccnc2N)CC1 +CCCc1nc2ccc(C(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CCCCC(=O)O)cc1 +CCCc1c[nH]c(C2Cc3ccccc3N2C(=O)C(N)CC)n1 +O=C1C(C(O)c2ccc3c(c2)OCCO3)CCCN1CC=Cc1ccccc1 +CN1CCN(C(=O)c2ccc(N3CCc4c(-c5cnc(N)nc5)nc(N5CCOCC5)nc43)cn2)CC1 +CCN(C(=O)Nc1ccc(N(C)C)cc1)C1Cc2ccc(SC(C)(C)C(=O)O)cc2C1 +NS(=O)(=O)c1cc(-c2csc(C(=O)NC3CCN(C(=O)OCc4ccccc4)CC3)n2)ccc1Cl +COc1cc(OC)c2nnc3c(C)nc(-c4ccccc4C(F)(F)F)n3c2c1 +CC(C)CC(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)C2CCNCC2)CC1 +CC(C)CCn1c(=O)n(C(=O)NC(C(N)=O)C(C)(C)C)c2ccccc21 +COc1cc(C(=O)N2CC(C)(CC(C)O)OCC2C)cc2nc(NC(CF)c3cccc(Cl)c3)oc12 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cccc(O)c1O +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2cc(C(F)(F)F)ccc2F)c1 +CCOP(=O)(OCC)C(C)(C)[N+]([O-])=Cc1ccccc1C(F)(F)F +CCC(C)c1c(Cc2c(F)cccc2Cl)nc(SCC(=O)c2ccc(F)cc2)[nH]c1=O +O=C1N(Cc2ccc3ccccc3c2)C(Cc2ccccc2)C(O)C(C(F)Cc2ccccc2)N1Cc1ccc2ccccc2c1 +Cc1cc(C2OC(CO)C(O)C(O)C2O)sc1Cc1ccc(Cl)cc1 +CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(-c2cnccn2)cc1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nnc(Nc2cccc(OCc3ccccn3)c2)o1 +O=P(O)(O)C(Nc1ccccc1)c1cccc2nc(O)c(O)nc12 +CN1CCN(c2ccc(C3Oc4ccc(O)cc4SC3c3ccc(O)cc3)cc2)CC1 +N=C(N)c1cccc(Oc2ccc3c4ccccc4n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)c1 +Cc1ccc(N2CN3C(=N2)C(=O)Nc2ccccc23)cc1 +O=C(NCCCO)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 +Cc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(-c3ccc(-c4ccccc4)cc3)cc12 +CN(C)C(=O)OC1CC2CC(NCC(=O)N3CCCC3C#N)CC2C1 +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3cc(C#N)c(C)cc3Cl)ccnc21 +CNC(C)C(=O)NC1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccccc2OC12CCOCC2 +Cc1c(C(=O)NCCCN2CCCC2)sc2ncnc(Nc3ccc(F)cc3OC(C)CF)c12 +Cc1nc2ccc(C(=O)c3cnn(C)c3O)cc2c(=O)n1-c1ccc(Cl)cc1 +CN(CC(CCN1CCC(O)(c2ccccc2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +C=CCN1CCN(C(c2ccccc2)c2ccc(C(=O)N(CCC)CCC)cc2)CC1 +Cc1c(Cl)cccc1N1CCN(CCCNC(=O)c2nc(C)n(-c3ccc4c(c3)OCCO4)c2C)CC1 +Cc1c2cccc-2c(N(C)C)cc2c1[nH]c1ccccc12 +C=CCCN1CCC(COc2nc3ccsc3n3cccc23)CC1 +Cc1cncc(-c2cc(Nc3nn(C)cc3Cl)nc3[nH]cc(C#N)c23)c1 +O=c1cc(-c2ccccc2)oc2cc(OCCCCCN3CCC(O)CC3)ccc12 +O=C1OCC2C1C=C1CCCCC1C2C=Cc1ccc2ccccc2n1 +CC(=O)NC(Cc1ccc(F)c(F)c1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +CC1=CC(C)(C)Nc2ccc3c(c21)C(C1C=CCCC1)Oc1c(F)cc(F)cc1-3 +COC(=O)C1CCN(c2cc(-c3c(N)nn4cccnc34)ncn2)C1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCC(=O)NCc3ccco3)[nH]c3ccc(Cl)cc23)c1 +CCCCc1ccc(C(=O)N(CCc2ccccc2)C(CC)c2nc3ccccc3c(=O)n2-c2ccccc2OC)cc1 +C=CC(=O)Nc1cccc(Sc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2Cl)c1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2ccnc2C1 +CC1CN(CC(Cc2ccccc2)C(=O)NC(CCCCN)C(=O)O)CCC1(C)c1cccc(O)c1 +O=C(NC1CCCC1OCc1ccccc1)C1CCN(c2nc3cc(Cl)ccc3o2)CC1 +COC1CCC2(CC1)Cc1ccc(-c3cc(Cl)cc(Cl)c3)cc1C21N=C(N)N(C)C1=O +Cc1cc(C=CC(=O)O)cc(C)c1NC(=O)c1cccc(NC(=N)N)c1 +[H]C([H])(NC(=O)c1nc(N)nc2c(OC)cccc12)c1cccc(C([H])([H])c2cncc(OCCOC)c2)n1 +NC(CC(=O)NC1(c2cccc(-c3nccs3)c2)CCS(=O)(=O)CC1)Cc1ccccc1F +CC(C)(C)c1cc(NC(=O)C2CCCN2C(=O)N2CCS(=O)(=O)CC2)no1 +CC(C)(CO)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 +CC1CN(Cc2c[nH]nc2-c2ccc3c(c2)CNC(=O)O3)CCN1c1ccc(C(F)(F)F)cc1 +COc1ccc(Cn2nnc(C(=O)NCCCCCN3CCN(c4ccccc4OC)CC3)c2C)cc1 +COC1C(=O)N2C(C(=O)OC(C)(C)C)=C(COC(=O)NC(Cc3ccccc3)C(=O)O)CS(=O)(=O)C12 +COc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1F +CN(C(=O)Cn1c(=O)n2c3c(cc(-c4ccccc4)cc31)CCC2)c1cccc(Cl)c1 +COc1ccc(-c2nc3c(c(Nc4cc(F)c(CC(=O)O)cc4F)n2)S(=O)(=O)CCC3)cc1F +CC(C)(C)OC(=O)N1CCN(C(=S)SCc2cn(Cc3cc(=O)oc4cc(O)ccc34)nn2)CC1 +Cc1nc(-c2cnccn2)sc1C(=O)Nc1ccc(C2CNCCO2)cc1 +O=C(c1ccccc1)N1CCN(CC(O)COCc2ccccc2)CC1 +Cc1nc(-c2cn3c(n2)-c2ccc(N4CCC4C4CCN(C)CC4)cc2OCC3)n(C(C)C)n1 +Cc1cc(Cc2ccc(Cl)c(Oc3ccccc3)c2)n[nH]c1=O +CCCNC1=NC(=O)C(=C2CCNC(=O)c3[nH]c(-c4ccccc4)cc32)N1 +CN(CCC(Oc1ccc(-c2ccccc2)cc1)c1ccccc1)CC(=O)O +CC(C)NC(=O)c1cccc2[nH]c(-c3n[nH]c4ncc(-c5cncc6ccccc56)cc34)nc12 +O=C(NCc1cncnc1)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +CC(=O)Nc1nc2ccc(-c3ccnc(Sc4ccc(F)cc4)n3)cc2s1 +N=C(N)c1cccc(Oc2ccc(NC(=O)Nc3ccccc3)c(Oc3cccc(C(=N)N)c3)n2)c1 +COc1cc(OCc2csc(C3(NC(=O)CN(C)C)CCOCC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CN(C(=O)Cn1c(=O)oc2ccc(-c3ccccc3)cc21)c1ccncc1 +CCC(C)(CC)NC1=NCCNC(c2ccc(F)cc2)=C1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC4CC4)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +COc1ccc(Oc2c(Cl)cnn(Cc3c(OC)ccc4ccccc34)c2=O)cc1 +N#Cc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 +CC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCCC2C(O)c1ccsc1 +CCc1coc(-c2ccc(OC)c3nc(C(F)(F)F)ccc23)n1 +CCN(C(=O)c1ccc(CO[N+](=O)[O-])cc1)C1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +O=c1ccn(-c2cc(-c3ccc(Cl)c(Cl)c3)ccn2)cc1O +O=C1CCc2c(Oc3ccc4c(c3)C3C(O4)C3c3nc4ccc(-c5ccccc5)cc4[nH]3)ccnc2N1 +CCCCCn1c(C)c(C(=O)c2ccc(CC)c3ccccc23)c2ccccc21 +CCN(C)C(=O)c1cnn(C)c1C(=O)Nc1ccc2nc(N(CC)CC)nn2c1 +CCc1ccc(C(C)=NNC(=O)CNC(=O)C=Cc2ccco2)cc1 +CCOC(=O)N1C2CCC1CC(O)(C#Cc1cccc(C)c1)C2 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+CCCNC(=O)c1c(NC(=O)c2c(F)cccc2C(F)(F)F)sc2c1CCOC2 +O=S(=O)(Nc1cc(Cl)ccc1Cn1ccnn1)c1csc2ccccc12 +CN(c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)C=Cc3ccc(Cl)s3)C2=O)nc1)S(C)(=O)=O +Cc1ccc(F)c(CNC(=O)Cc2c(C)n[nH]c2C)c1Cl +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCC(N2CCCC2)CC1 +Cc1cccc(Nc2cc(NC3CCCCC3N)nnc2C(N)=O)n1 +COC1CC(C(C)C)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +Cc1c(C=CN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(c1ccc2[nH]ccc2c1)n1nnc2c(N)nc(C3CC3)nc21 +O=C(OCC(COC(=O)c1cc(O)c(O)c(Br)c1)OC(=O)c1cc(O)c(O)c(Br)c1)c1cc(O)c(O)c(Br)c1 +CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OC)c(F)c1 +CN1c2cc3c(cc2C2CCCC(C)(C)C21)c(C(F)(F)F)cc(=O)n3C +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CC(C)(C)C=C(C)C +Cn1nnnc1-c1cccc(NC(=O)NC2CCCCC2CNCCCc2ccc(F)cc2)c1 +CC(=O)Nc1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(C)c(COc3cccc4ccc(C)nc34)c2C)cn1 +COc1ncc(-c2cc(OC(C)C3CNC(=O)C3)c3cccnc3c2)cc1F +N=C(N)Nc1cccc(C(=O)Nc2ccc(C=CC(=O)O)c(C(=O)O)c2)c1 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+CC1(C)CC=C(c2cc(C3(O)CCCC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +O=S(=O)(Nc1ccc2ccn(CCN3CCCC3)c2c1)c1c(Cl)nc2sccn12 +NC1=CC(=O)c2ccc(-c3[nH]c(CO)cc4c5ccccc5nc3-4)nc2C1=O +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1 +COc1cccc(C=Cc2nnc(NC(=O)c3cc(OC)c(OC)c(OC)c3Br)s2)c1 +Cc1ccc2[nH]c(C(=O)NCCCCCCC(=O)NO)cc2c1 +CC(O)C1CCC2(O)C3CCC4CC(OCC5OC(OCC6OC(O)CC(O)C6O)CC(O)C5O)CCC4(C)C3CCC12C +CS(=O)(=O)c1ccc(-c2c(-c3ccccc3)sc3nncn23)cc1 +Cc1ncc(C#Cc2c(C)ncnc2N2CCOCC2)cc1NS(=O)(=O)c1cnoc1C +[C-]#[N+]C(C)(C)CC1CC(C)C2CCC(C)([N+]#[C-])C3CCC(=C)C1C23 +COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)C2=NCCC2)c1Cl +CC12C=CCC3(C)C(=O)OC(C13)C1OC13COC(=O)C=C23 +C=C(C)C1CCC2(NC(=O)NCCOCCO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +O=C(c1cc(-n2ccc3ccccc32)c(O)cc1O)N1CCc2sccc2C1 +CC(C)(CN)C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +Cc1nc(C(C)(C)NC(=O)c2cccc(-c3ccc(Cl)c(F)c3)n2)no1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(N(CC)C(C(=O)O)c2ccccc2Cl)cc1 +CCCCCCCCCCCCn1nnc(C(Cc2ccccc2)S(=O)(=O)Nc2c(C(C)C)cccc2C(C)C)n1 +CNC(=O)CN1N=C(c2ccccc2)C2(CCN(C3CCC4CCCCC4C3)CC2)C1=O +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(C#N)c(-c2cnc3ccccn23)n1 +COc1ccc(S(=O)(=O)N(CC(=O)O)C(C(=O)NO)C(C)C)cc1 +CC(c1ccccc1)N1CCC2(CC1)OC(CF)c1ccccc12 +c1ccc2c(c1)CC2CCCN1CCN(c2cccc3c2OCCO3)CC1 +CCCOc1ccc(F)c(-c2cccc(C(=O)Nc3cnccc3C3CCC(O)C(N)C3)n2)c1 +O=C(Nc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(C(O)C(F)F)cc2)c1)c1ccc(Cl)cc1 +O=C(Nc1cccc(Oc2cccc3[nH]c(=O)[nH]c23)c1)c1ccc(F)c(OC(F)(F)F)c1 +NC1CCCCCCC(C(=O)NCc2ccccc2CC(=O)O)NC(=O)C(Cc2ccc(O)cc2)NC1=O +COc1cnn(CC(=O)C2CCC3C4CCC5CC(C)(O)CCC5C4CCC23C)c1 +O=c1cc(-c2ccc(O)c(O)c2)oc2c1ccc1ccccc12 +O=C(NC(Cc1ccc(-c2ccccc2)cc1)C(=O)O)C(CS)Cc1ccccc1 +CC(C)(C)c1ccc(-c2cnnc(Nc3ccc4c(c3)OCCO4)c2)cc1 +Cc1cc(C(N)=O)c2nc(-c3ccc(C4(N)CCC4)cc3)c(-c3ccccc3)n2c1 +COc1cc2c3c(-c4cccc(O)c4)c[nH]c(=O)c3n(C)c2cc1OC +Fc1cc(F)c(CN2CCN(c3nc4ccncc4nc3Nc3cccnc3)CC2)cc1F +Cc1ccc(OCC(=O)Nc2ccc(-c3nc4cc(C)cc(C)c4o3)cc2)cc1 +Cc1cc(-c2cc(F)cc(Cl)c2)ncc1C1CCCN1C(=O)c1cnccn1 +CN(C)C(=O)c1ccc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1Cl +CCC1=C2C3C=C(C)CC2(NC1)c1ccc(O)nc1C3 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCc3cccnc3)[nH]c3ccc(Cl)cc23)c1 +Cc1ccc(SCc2noc(-c3c(C)noc3C)n2)cc1 +OC12C3C4CC5C6C4C1C6C(C53)N2Cc1cccc(Cl)c1 +CCOC(=O)c1cn2c3c(nc(O)c2n1)-c1ccc(NC(=O)NC)cc1C3 +CC(C)CS(=O)(=O)Nc1ccc(CN2CCC(CNC(=O)c3cccc4c3OCCO4)CC2)cc1 +NS(=O)(=O)c1c(F)cccc1NS(=O)(=O)C=Cc1ccc(-c2cc3ccccc3o2)cc1 +NS(=O)(=O)c1cccc2c1C(=O)C=C(Nc1ccccc1N1CCNCC1)C2=O +CN(Cc1ccc2c(c1)OCO2)C1C2C3CC4C5C3CC2C5C41 +COc1ccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc2c1 +CN(C)S(=O)(=O)Oc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +NC1CCN(c2nc(Nc3cc(C4CC4)[nH]n3)c3occc3n2)CC1 +O=C(NCc1ccccc1)c1ccc2cc(-c3n[nH]c4ccccc34)[nH]c2c1 +CN(C)C(=O)c1ccc(C(O)(c2ccccc2)c2ccc(C(=O)NCCCCCCC(=O)NO)cc2)cc1 +CC(CCc1ccc(-c2ccc3c(c2)C(=O)NC3)cc1)(C(=O)NO)S(C)(=O)=O +CNC(=O)C(NC(=O)c1ccc(-c2ccc(Cl)cn2)o1)C1CCCCC1 +CC(C(=O)Nc1cc(C2CC2)[nH]n1)c1ccc(N2CC(=O)NC2=O)cc1 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+Cc1ccc(OCc2ccccc2C(=O)Nc2ccc3nc(C)cc(N)c3c2)cc1 +CCN1CCCC1CNc1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 +O=C1CC(C(=O)Nc2cc(-c3cc(F)cc(COCC(F)(F)F)c3)n(-c3cccc(F)c3)n2)CN1 +CCOCC=Cc1ccc(-c2nc(-c3ccc(NC(C)C)cc3)c(-c3ccc(NC(C)C)cc3)[nH]2)cc1 +CC(C)C(NS(=O)(=O)c1cccc(Br)c1)C1=CC(=O)c2c(O)ccc(O)c2C1=O +COC(=O)NC(C(=O)NN(CCCC(O)(Cc1ccccc1)C(=O)NC1c2ccccc2CC1O)CC(C)C)C(C)(C)C +Cc1[nH]c(C(=O)NC2CCN(c3ncc(C(=O)O)s3)CC2Cl)c(Cl)c1Cl +CC(=O)NCCCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1ccc(F)cc1F +O=C(NO)c1ccc(CN2c3ccccc3NC(=O)C2CCc2ccccc2)cc1 +O=C(CN1CCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)[nH]c23)c2sc3ccccc3c12 +CC1CCN(C(=O)c2sc(-c3ccc(S(C)(=O)=O)c([N+](=O)[O-])c3)nc2C(F)(F)F)CC1 +N#Cc1ccnc(N2CCC(S(=O)(=O)c3ccccc3C(F)(F)F)C2)n1 +COc1nc(N2CC(O)C2)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +CC(C)c1cccc(NC(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +O=C(O)CCSC(CCc1ccccc1-c1nc[nH]n1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 +CCn1cc(-c2ccc3cnc(Nc4ccc(-c5cnc(C)n5C)cc4OC)cc3c2)cn1 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+COc1cccc(-c2cccc(CN3CCN(c4ncccn4)CC3)c2)c1 +Cc1ncc(C(=O)NCc2ccccc2N2CCN(C)CC2)cc1NC(=O)c1cnn2cc(-c3ccnn3C)ccc12 +O=C1c2ccc(Nc3ccc(F)cc3F)cc2CCc2ccc(OC3CCOCC3)cc21 +COc1ccc(Nc2nc(N3CCC(C(=O)Nc4ccc(C(=O)O)cc4)C3)nc3scnc23)cc1OC +O=[N+]([O-])c1ccc(-c2nn(-c3ccc(Br)cc3)cc2C=NNC(=S)Nc2ccccc2)cc1 +CC1CN(c2ccc(C(=O)Nc3ccccc3N)cn2)CCN1C(=O)NCCc1ccccc1 +O=C1CCC(CCN2CC(N3CCNCC3)C2)(c2ccc(Cl)c(Cl)c2)CN1CC1CC1 +CCc1[nH]cc2c1NC1=C(C(=O)CNC1)C2c1cccc(Sc2nc3ccccc3[nH]2)c1 +CN(C)CCN(C)C(=O)c1ccc2c(c1)-c1nc(N)nc(-c3ccccc3)c1C2=O +O=C(NC1CCN(Cc2cc3c(cc2Cl)OCO3)CC1)c1cc(=O)c2ccc(F)cc2o1 +COc1ccc2[nH]c(-c3cc[se]c3)cc(=O)c2c1O +COCCN1CC(=O)Nc2ncc(-c3ccc(-c4nc[nH]n4)nc3C)nc21 +CCCCCCCCc1cc(Cc2ccc(F)cc2)c(C=C2N=C(c3ccc[nH]3)C=C2OC)[nH]1 +O=C(C=Cc1cnccc1-c1cnn(C2CC2)c1)Nc1ccc(CN2CC(F)(F)C2)cc1 +CN1C(=O)N(CCN2CCOCC2)CC1C(=O)NCc1cccc(C(F)(F)F)c1Cl +CCc1cc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)c2cc(OCC(F)(F)F)ccc2n1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)N1CSCC1C(=O)NC(C=O)CCCN=C(N)N 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+c1cc(-c2n[nH]c3cnc(-c4cncs4)cc23)nc(N2CCCCC2)c1 +O=c1[nH]c2ncc(-c3ccc(-n4cccn4)cc3)nc2n1CC1CCOCC1 +CCOC(O)=C1C(COCc2cc(O)nc(SC)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +N#CC1(c2ccccc2OC(F)(F)F)CCC(CNc2ncccc2NC(=O)CC(F)(F)F)CC1 +CCCCCCOC(=O)C(C)NP(=O)(OCC1OC(n2cc(F)c(=O)[nH]c2=O)CC1O)Oc1cccc2ccccc12 +Cn1c(=O)n(C2CCC(C(=O)OCc3ccccc3)CC2)c2c3nc(-c4cnc5ccccc5c4)ccc3ncc21 +Cc1nc2cc(-n3ncc(C(=O)c4cc5ccc(-c6cccs6)cc5[nH]4)c3N)ccc2[nH]1 +O=C(NO)C1CCCC1C(=O)Nc1ccc(OCc2ccncc2)cc1 +O=C1NCc2ccc(OCCCCN3CCN(c4cccc5ccccc45)CC3)c(F)c21 +CC(=O)Nc1cccc(Nc2ncnc(N3CCC(OCc4ccc(C(F)(F)F)cc4)CC3)n2)c1C +N#Cc1ccnc(N2CCC(S(=O)(=O)c3ccc(N4CCN5CCCC5C4)cc3Cl)C2)n1 +CCN1CCCC1CNC(=O)c1ccc(-c2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)s1 +NC(=O)c1ccc2sc(-c3c(NC4CCCNC4)nc(N4CCOCC4)[nH]c3=O)nc2c1 +CCCc1ccccc1Oc1ccc(-c2nc(-c3sc(CN4CC(C(=O)O)C4)cc3CC)no2)cc1 +CN1CCC(c2ccc(Cl)cc2)C(CC(=O)NC23CC4CC(CC(C4)C2)C3)C1 +COC(C)(C)CCn1nc(Nc2c(C)cc(F)cc2C)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc21 +NC(=O)Nc1cccc2c1C(=O)c1c(C3CC3)n[nH]c1-2 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+CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4ccc5c(c4)CCC(N4CCOCC4)CC5)nc23)cc1 +COc1cc2ncc3c(c2cc1CCc1ccsc1)n(-c1ccc(C#N)cc1F)c(=O)n3C +Cc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(OCCc3ccccn3)nc1)CC2 +CC(O)C(O)c1cnc(N2CCN(C(=O)Nc3nc4ccc(F)cc4s3)C(C)C2)c(F)c1 +Cc1ccc(C(=O)Nc2ccon2)cc1Nc1nc(N)nc(NC2CCCC2)c1C#N +Cc1ccccc1N1CCc2c(C)nc3c(F)cccc3c21 +CCC(CC)OC1C=C(C(=O)O)CC(NCc2cccs2)C1NC(C)=O +O=S(=O)(Nc1nccs1)c1ccc(Nc2nncc3ccccc23)cc1 +CC1(C)Cc2cc3c(C(F)(F)F)cc(O)nc3cc2NC1(C)C +CCCCCCCCC(CC(=O)NO)C(=O)NC1CCCCN(CCOC)C1=O +C=CCCCCCCOc1ccc(C(=O)Nc2cccc3c(=O)cc(-c4nn[nH]n4)oc23)cc1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cccc(C)c21 +Cc1c(C)n(Cc2cccc(C(=O)O)c2)c2ccc(C(=O)NC(C)c3cccc(C4CC4)c3)cc12 +CN1CCC(n2cnc(-c3ccc(F)cc3)c2-c2ccnc(Nc3ccncc3)n2)CC1 +CC#CC(=O)N1CCC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)CC1 +c1cc2cc(CN3CCCNCCNCCCNCC3)ccc2cc1CN1CCCNCCNCCCNCC1 +N#Cc1cc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)ccc1F +O=C(O)C1=CCCN(C2CCC3(Cc4ccccc4Cc4ccccc43)C2)C1 +NC(=O)Nc1cc(-c2cccc(F)c2F)sc1C(=O)NC1CCCNC1 +O=C(NCCCCCCS)c1cc(-c2ccc(F)cc2)n(CCCCO)n1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C4CC4)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +COc1cccc(C2OC(CC(=O)NCCCC(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC +COc1cc(C(=O)O)ccc1Cc1cn(CC2CC2)c2ccc(NC(=O)OC3CCCC3)cc12 +CC(Nc1ncnc2c(C(N)=O)cccc12)C1=CC(NC(=O)C2(C(F)(F)F)CCC2)=CCC1 +Cc1ncc(C)n2nc(-c3ccn4cc(-c5cccc(C6CC6)c5)nc4c3)nc12 +Cn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(F)cc4)cc3=O)cc21 +CC(C)OC(=O)c1nc2ccc3ncnc(Nc4ccc5c(c4)OCO5)c3c2s1 +O=C(c1cc(-c2ccccc2)nc(-c2ccccc2)c1)N1CCN(C2CCN(C(=O)N3CCCCC3)CC2)CC1 +N#Cc1cccc(-n2nc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)c(C(=O)O)c2-c2ccccc2)c1 +CS(=O)(=O)N1CCN(CCCCOc2cccc(NC(=O)CC34CC5CC(CC(C5)C3)C4)c2)CC1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Nc3ccc(N4CCOCC4)cc3)n2)n[nH]1 +O=C(C=Cc1ccccc1)OC1C(O)C(CO)OC(Oc2c(O)cc3oc4cc(O)c(O)cc4c(=O)c3c2O)C1O +CCC(=O)Nc1cc(-c2ccccc2F)nc(-c2ccccc2F)n1 +CC(C)=CCCC(C)=CCc1c(O)ccc(C2COc3cc(O)cc(O)c3C2=O)c1O +COc1ncc(-c2cnc3[nH]cc(C(=O)c4c(F)ccc(NS(=O)(=O)c5cccc(F)c5)c4F)c3c2)cn1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(Nc2ncc(C(F)(F)F)cc2Cl)c1 +O=C1OC(Cn2cc[n+]3ccccc23)CC1(c1ccccc1)c1ccccc1 +COc1ccc(C(O)CC2NCCc3cc(OC)c(OC)cc32)cc1 +O=C(c1ccc(-c2cccs2)cc1)N1CCn2c(nnc2-c2ccccn2)C1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ccncn3)cs2)CO1 +Cc1cc(Nc2nc(NC3CCCCC3N)nnc2C(N)=O)cc2cccnc12 +CNC(=O)OCCc1ccc(Cl)c(CN(C(=O)C2CNCCC2c2ccc(OCCOc3c(Cl)cc(C)cc3Cl)cc2)C2CC2)c1 +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)nc1 +Cc1cc(-c2c(F)cc3c4nn(C5CCOCC5)c(=O)c-4cn(C4CC4)c3c2F)cc(C)n1 +CCOC(=O)c1ccc(CCc2nc3cccc4c3n2CCNC4=O)cc1 +CC(C)c1ccccc1Sc1ccc(C2CC2C(=O)N2CCC(C(=O)O)CC2)c(Cl)c1Cl +Cc1cc(C)nc(N2CC3CN(C(=O)c4cc(Cl)ccc4C)CC3C2)n1 +CC1(C)Oc2cc(C34CC5CC(CC(C#N)(C5)C3)C4)cc(O)c2C2CC(O)CCC21 +CCCN(CCC1CCC(NC(=O)c2ccc(-n3cncn3)cc2)CC1)C1CCc2nc(N)sc2C1 +CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(S(=O)(=O)Nc4ccc(OCCCc5ccccc5)cc4F)cc3C2)cc1 +O=C(Nc1nc2ccc(O)cc2s1)c1cccc(O)c1F +Cc1ccc(S(=O)(=O)N2CCSC2C(=O)NC(C=O)Cc2ccccc2)cc1 +COC(C(=O)NC1CCC(OC(=O)c2ccccc2)CNC1=O)C(O)C(O)C(O)C=CC(C)(C)C 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+CC(C)NC(=O)c1cn(-c2cccc(-c3ccc(S(C)(=O)=O)cc3)c2)c2ncccc2c1=O +O=C(NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1)C1CCN1 +CC(=O)N(CCCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)CC1CCCCC1 +O=C1CC(C(=O)Nc2cc(-c3cccc(C(F)(F)F)c3)n(-c3ccccc3F)n2)CN1 +CNCc1cc(-c2ccc3c(N)cc4n[nH]c(=O)n4c3c2)cs1 +CCOC(=O)c1c(C#N)csc1NC(=O)Cc1ccc(OC)cc1 +CNC(=O)C(NC(=O)c1ccc(-c2ccc(NC(=O)c3cc(C)c(C)o3)cc2)o1)C1CCCCC1 +CCCC(=O)N1CCC(c2ccc(Cl)cc2)C1C(=O)N1CCN(c2ccc(C)cc2C(N)C(C)C)CC1 +COCCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2c1)c1ccccc1 +COc1cc(OCC(=O)Nc2ccc(Br)cc2)ccc1-c1cc2c([nH]1)c(=O)n(C)c(=O)n2C +CCOC(=O)C=CC(CC1CCCNC1=O)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(C4CCN(C)CC4)nc3)NC(=O)NC1=O)C2 +CN1CCN(c2cccc(N(Cc3ccccc3)S(=O)(=O)c3ccc4ccccc4c3)c2)CC1 +CN(C)CC1CCn2c(c(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)c3ccccc32)C1 +Cc1cnc2nc(SCc3cccc(F)c3F)nc(NC(C)CO)c2n1 +O=C1NC(=O)C(c2ccc(Cl)cc2)=C1Nc1cc(Cl)c(O)c(Cl)c1 +CC=CCNc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1 +CCNC(=O)C1OC(n2cnc3c(N)nc(NCCN4CCN(c5ccccc5F)CC4)nc32)C(O)C1O +CC(C)(C)c1ccccc1N1CCN(C(=O)C(O)CO)CC1 +Cc1c(-c2ccc(Cl)cc2)nc(O)n1C1CCN(Cc2ccccc2)CC1 +OCC1OC(n2cnc3c(SCc4ccc(Cl)c(Cl)c4)ncnc32)C(O)C1O +Cc1cc(OCc2cc(-c3ccc(Cl)cc3)on2)cc2scc(CC(=O)O)c12 +Cc1ccc(C(=C(CCCO)c2cccc(F)c2)c2ccc(OCCN(C)C)cc2)cc1 +CN(C)Cc1ccc(-c2cc3c(-c4cnn(C)c4)c(Cl)cnc3[nH]2)cc1 +Nc1nc(N2CC3CC2CN3)c2oc3ccc(Cl)cc3c2n1 +CCOC(=O)C(Cc1cc2ccnc(N)c2cc1OCCOC)N1CCC(NS(=O)(=O)c2cnc(N(C)C)s2)C1=O +CC(C)S(=O)(=O)n1c(N)nc2ccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)cc21 +CC1=NN(C(=O)c2ccccc2O)C(=O)C1=Cc1cccc(O)c1 +COc1ccc(-c2cc(-c3c[nH]c4ccccc34)nc(N)c2C#N)c(OC)c1OC +NC(=O)c1nnc(NC2CCOCC2N)nc1Nc1cccc2c1ccn2C1CCC1 +CCC(c1c(Cl)c(Cl)cc2nc(O)c(O)nc12)n1ccnn1 +COC1Cc2cc(-c3ccc(C)cc3)sc2C2(CCN(Cc3ccccc3)CC2)O1 +Cc1cc(-c2ccccc2)cc(C)[n+]1CC(=O)Nc1nnc(S(N)(=O)=O)s1 +CCN1C(=O)c2nc(-c3ccc(F)c(C#N)c3)n(Cc3ccc(F)c(F)c3)c2N2CC(C(C)C)N=C12 +CN1C(=O)c2ccc(F)cc2C2(CC(=O)NC2=O)C1=O +CC(C)(F)CC(NC(c1ccc(-c2ccc(C3(C(N)=O)CC3)cc2F)cc1)C(F)F)C(=O)NC1(C#N)CC1 +O=C(NCCN1CCOCC1)c1cccc(-n2ncc3cc(Nc4ccccc4)cnc32)c1 +COC(=O)C(NCc1cc2ccccc2c(-c2c(O)c(CNC(C(=O)OC)C(C)C)cc3ccccc23)c1O)C(C)C +CCOC(=O)C(=O)N1c2ccc(C)cc2-c2c(ssc2=S)C1(C)C +COc1cc(Cl)c(Cc2ncc(-c3cccs3)s2)cc1C1OC(CO)C(O)C(O)C1O +COC(=O)N1CCN(c2ccc(NC(=O)c3nc(-c4ccccc4)oc3C(F)(F)F)cc2)CC1 +CCS(=O)(=O)c1ccc2[nH]c(-c3cccc(-c4ccccc4)c3Cl)nc2c1 +Nc1noc2cccc(-c3ccc(NC(=O)Nc4cccc([N+](=O)[O-])c4)cc3)c12 +O=C(NCCCF)c1c[nH]c2ccc(Cc3ccccc3)cc2c1=O +CCOC(=O)C1=C(CN2CCOCC2C(=O)OC(C)C)NC(c2nccs2)=NC1c1ccc(F)cc1Br +N#Cc1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1Oc1ccc(F)c(F)c1 +CN(C)CCn1c(Cn2nc3ccccc3n2)nc2ccccc21 +Cc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccccc2I)c(C)c1 +CC=C1CN(C(=O)C(CCCCNC(=N)N)NC(=O)c2ccccc2)C(C(=O)NC(CC(C)C)C(=O)O)C1C +CCCCCS(=O)(=O)NC(=O)C=Cc1ccc(OCCOC2CC2)cc1Oc1ncc(C(F)(F)F)cc1Cl +CCCCCCCCCOC(=O)C1CN(CC)CC=C1c1ccccc1 +CC(=O)c1ccc(C=Cc2cc3c(c(=O)n(C)c(=O)n3C)n2C)cc1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC2(c3ccccc3)CCCC2)c1 +Cc1cc(COc2ccc(S(=O)(=O)N(C)C3COCC3C(=O)NO)cc2)c2ccccc2n1 +CC(C)Cc1ccc(C(C)c2nc3cc(OCc4ccccc4C#N)ccc3n2Cc2ccccc2Cl)cc1 +COc1ccc(CC(=O)NNC(=O)Cn2c(C)nc3ccccc32)cc1 +Cc1cc(S(C)(=O)=NC#N)ccc1CNC(=O)c1cn(C(C)C)c(C)c(-c2cccc(C(F)F)c2)c1=O +CC1(C)CC(NC(=O)CO)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2O1 +O=C(CCCCNC(=O)c1csc(-c2cscn2)n1)NO +N#Cc1ccc(Oc2ccc3c(Cn4ccnc4)cc(=O)oc3c2)cc1 +Cc1ccccc1-c1c(C#N)c(N)nc2sc(C#N)c(N)c12 +Cc1ccc(Nc2ncnn3cc(C(=O)NCCCN4CCOCC4)c(C)c23)cc1O +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)c5ccon5)C4)c3C2)cc1C +Cc1cccc(NC(=O)Nc2ccc(C#Cc3ccc4nc(N)cn4n3)cc2)c1 +CN(CC(CCN1CCC2(CC1)CS(=O)(=O)c1ccccc12)c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccccc1 +O=C(CSc1nnc(Nc2ccccc2)s1)NN=Cc1ccc(-c2ccc(Cl)cc2)o1 +CNC(=O)C1CSc2ccccc2NC(=O)COC(C(=O)NO)C(CC(C)C)C(=O)N1 +COc1cc(OC)cc(N(CCCN2CCC(S(C)(=O)=O)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CSc1nn2c(C)c(Cl)c(C)nc2c1S(=O)(=O)c1ccccc1 +NC1CN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1c1ccc(F)cc1 +CC(C)(C)c1ccc2c(c1)C1OCCCC1C(c1ccc(Cl)s1)N2 +COCCN(C(=O)c1cnc(-c2ccccc2C)cn1)c1ccc(OC)nc1 +CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CC3CCC(C3)C2)cc1 +O=C(O)c1cc(-c2ccc(CNS(=O)(=O)c3ccc(OC(F)(F)F)cc3)cc2)n(-c2ccc(Cl)c(Cl)c2)n1 +CN(C)c1ccc(-c2cnc3cc(OCCF)ccc3n2)cc1 +Fc1ccc(N2CCN(CCC(Oc3ccc(C(F)(F)F)cc3)c3ccccc3)CC2)cc1 +Cc1nn(Cc2ccccc2)c(Cl)c1C(=O)NCCc1ccccc1 +CCC(CC)Sc1nc2cc(Cl)c(N3CCN(CCO)CC3)cc2[nH]1 +Cn1cc(C(C(=O)Nc2ccc3ccccc3c2)P(=O)(O)O)c2cc(Cl)ccc21 +CC(C)C(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2c1)c1ccccc1 +CN1C(=O)NC(=O)C12Cc1ccc(NC(=O)Cn3c(=O)n(-c4ncccn4)c4ccccc43)cc1C2 +Cc1nnc2sc(C(=O)NC3CN(c4nc5cccnc5s4)C3)c(N)c2c1C +Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccccc4)cc3=O)cn12 +Cn1cc(C2=C(c3cccnc3)C(=O)NC2=O)c2ccccc21 +COC(=O)C1CC(NS(C)(=O)=O)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2nc(C(F)(F)F)co2)CC1c1ccc(C(F)(F)F)s1 +CCn1nc(-c2ccc(Cl)cc2)cc1C1CCN(CCc2ccccc2)CC1 +Cc1cccc(-c2nn(CC(=O)Nc3cccc(C#N)c3)cc2-c2ccc3ncnn3c2)n1 +O=C(CCCNC(=O)C(Cc1ccc(O)c(Br)c1)=NO)NO +Cc1cncc(Oc2ccc(Cn3cc(C(=O)NCc4c(C)cc(N)nc4C)cn3)cc2)n1 +CCN(CC)C(=O)C1CNC(C(=O)N2CCCC2C#N)C1 +CCNC(=O)C1OC(n2cnc3c(NCCCCCCNS(=O)(=O)c4cccc5c(N(C)C)cccc45)ncnc32)C(C)C1C +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2c(F)cccc2F)C1 +CC(=O)OC1OCCC1NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)c1ccc2c(c1)Nc1ccccc1S2 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1ccc(OC(F)F)c(F)c1 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)c2cc1OCCOC +Cc1cc(=O)oc2cc(NC(=O)c3ccccc3Cl)ccc12 +O=C(COc1ccc(Cl)cc1)Nc1nnc(-c2ccc3c(c2)CCCC3)o1 +Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cc(F)cc(Cl)c2)C(N)CC3)c1 +Clc1cccc(Nc2nccc(-c3cccc(N4CCNCC4)c3)n2)c1 +Cc1ccc(Sc2ccccc2CSC(=N)N)c(CSC(=N)N)c1 +O=C(CCCCCONC(=O)Nc1cccc2cccnc12)NO +CNc1nc(NCc2ccc(OC(F)(F)F)cc2)cc(-c2ccccn2)n1 +N#Cc1ccc(-n2nc(C(N)=O)c3ccc4[nH]ncc4c32)cc1 +Cc1cc(C#N)cc(NC(C)c2cc(C(=O)N(C)C)cc3c(=O)cc(N4CCOCC4)oc23)c1 +COc1cc(NC(=O)C2CC(F)CN2C(=O)Nc2cn(C(N)=O)c3ccccc23)ccn1 +Cc1ccc2nc(N3C(=O)C(O)=C(C(=O)c4ccco4)C3c3ccc(C)o3)sc2c1 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+CN(C)CC1CCN(C(=O)Nc2nc3c(s2)-c2nc(C(C)(C)C)ncc2CC3)C1C(N)=O +CC(O)CSc1nc2c(c(Nc3ccc4c(c3)N(C)CCC4(C)C)n1)CCN(c1ncccc1C(F)(F)F)CC2 +CN1Cc2c(C3CCN(CC(=O)O)CC3)[nH]c3nccc(c23)-c2cc(F)ccc21 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)c2cc1OCCN1CCCCC1 +CC(C)c1cccc2c3c(n(Cc4ccc(Cl)cc4)c12)C(CC(=O)O)CCC3 +CN1CCC(N(C)C(=O)C2CN(S(=O)(=O)c3cccs3)c3ccccc32)CC1 +FCCn1cc(-c2ccncc2)c(-c2ccc(OCc3ncccc3F)cc2)n1 +O=C(C=Cc1cccn(CC=Cc2cccc(C(F)(F)F)c2)c1=O)NO +C=CCN(CCC(=O)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1)CCC1c2ccccc2-c2ccccc21 +CSc1cnn2c(NCc3cccnc3)cc(-c3ccccc3)nc12 +CC(=O)N1CCC(c2nc(-c3cc4ccccc4[nH]3)c3c(N)nccn23)CC1 +CCCCN1C(=O)CC(C(=O)OC2CC3CCC(C2)N3C)c2ccccc21 +CSc1cc(C)nc(SC)c1NC(=O)N(Cc1ccc(Oc2ccc(F)cc2)cc1)Cc1c(C)cccc1C +Cc1cc(N)nc(CCc2cccc(C(CN)Cc3cc(C)cc(N)n3)n2)c1 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccn(O)c(=O)c2)cc1 +CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4cccnc4)ccc3Sc3ccc(N)cc3)ncnc2n1 +Nc1n[nH]c2cccc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(F)c3)c12 +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(OC(=O)Cc2ccccc2Cl)c1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(NC(C)C)cc3OC)ncc2Cl)c1 +CCCC(=O)OC1=C(c2ccccc2)Sc2ccccc2-n2cccc21 +NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(NC(=O)c3c(F)c(F)cc(F)c3F)cc2)cc1 +CCC1(OC(=O)CCC(P(=O)(O)O)P(=O)(O)O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 +CC(C=NOCCN)=CC1CCC2(O)C3CCC4CC(O)CCC4(C)C3CCC12C +CC1CN(C)CCc2ccc(Nc3ncc(Cl)c(NC4C5C=CC(C5)C4C(N)=O)n3)cc21 +NC1CCC(Nc2cc(-c3cccc(NCC4CCCCC4)n3)c(Cl)cn2)CC1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccc2ccccc2c1 +Cc1[nH]c(C(=O)NC2CCN(c3nnco3)CC2)c(Cl)c1Cl +COc1cc(Cc2c(-c3ccc(NC(=O)CN4CCS(=O)(=O)CC4)cc3)sc3cc(O)ccc23)ccc1CN1CCCC1 +Cc1cc(COc2ccc(S(=O)(=O)C3(C(=O)NO)CCN(C=O)CC3)cc2)c2ccccc2n1 +COCCCC(=O)NCCN1CCCC1Cn1nc(Cc2ccc(Cl)cc2)c2ccccc2c1=O +COc1cccc(CC2(N)CCN(c3ncnc4[nH]ccc34)CC2)c1 +CCc1c(Sc2ccc3ccccc3c2)[nH]c2nc(N)nc(N)c12 +COc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1Br +Cc1sc(-c2cccc3ccccc23)cc1C(=O)N1CCC(CO)CC1 +CC1(O)CCC2CC1OOC2(C)CS(=O)(=O)c1ccc(F)cc1 +N=C(N)NCCCC1NC(CNC(=O)c2ccc3ccccc3c2)CCN(CC(c2ccccc2)c2ccccc2)C1=O +Cc1cc(C(=O)NCc2cc(Cl)ccc2-n2cnnn2)cc(C2CNCCC2CC(C)C)c1 +N#CC(Cc1ccc(-c2ccc3c(c2)CNC3=O)cc1F)NC(=O)C1NC2CC1C1CC21 +CCN(CC)c1ccc(-c2cc(-c3ccc(C(=O)O)cc3)ccc2OCCCCO)cc1C(C)(C)C +CCCCOC(=O)NS(=O)(=O)c1cc(CC(C)C)ccc1-c1ccc(C(=O)N(CC)CC)cc1 +CC1CN(CCc2ccccc2)CCC1(C)c1cccc(C(N)=O)c1 +CNC(=O)C12CC1C(n1cnc3c(NCc4cccc(Cl)c4)nc(I)nc31)C(O)C2O +O=c1[nH]c(CCCN2CC=C(c3ccccc3)CC2)nc2ccccc12 +O=C(O)Cc1ccc2c(c1)Cc1c-2nc(O)c2nc(C(=O)O)cn12 +CCCNC(C)Cc1ccc(OC)c(OCCc2ccccc2)c1 +CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)cn1C1CC2C1)CF +CCN1CCC(NC(=O)c2csc(NC(=O)c3ccc4cc5n(c4c3)C(C)CNC5=O)n2)CC1 +CCNc1cc(-c2nc(C(F)(F)F)nc3c(-n4cnc(-c5cnn(C)c5)c4)cccc23)ccc1C(N)=O +CC(C)CC(=O)OCC1(CO)CC(=CCC(CC(C)C)CC(C)C)C(=O)O1 +O=C(C1CC1)N1Cc2n[nH]c(=O)c3cccc4[nH]c(c2c43)C1 +CC(C)C1CCCC(COC(=O)N2CCN(CCO)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +Cn1cc(C(=O)Nc2cc(Cl)c(CC(=O)N3CC(O)CC3COC3CCC(C(=O)O)CC3)cc2Cl)c2ccccc21 +Cc1onc(-c2cc(F)ccc2F)c1COc1ccc(C(=O)NC(C)C)cn1 +O=C(c1ccccn1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NC(C)C(=O)O +OC1=C2C(=Nc3cc4c(cc3C2c2ccc3c(c2)OCO3)OCO4)CO1 +C=C(C)C12CC(C)C34OC(CCCCCCCCC)(OC1C3C1OC1(CO)C(O)C1(O)C(=O)C(C)=CC14)O2 +C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(Br)c(Cl)c3F)ncnc2cc1OC +CCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O +COc1ccccc1-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1 +COc1ccc(C2CC(=O)N(c3cccc(NS(=O)(=O)c4cc(Br)c(Cl)s4)c3)C2)cc1OC1CCCC1 +CCN(CC)c1ccc2cc(C(=O)c3ccc(NS(=O)(=O)c4ccccc4)cc3)c(=O)oc2c1 +C(#Cc1ccc(C(N2CCOCC2)N2CCOCC2)cc1)c1ccccc1 +CC(=O)NCCc1c(C2CC2)nn2ccc3c(c12)CCO3 +CCCCCC(O)c1ccc(C2CCC(=O)C2CCCCCCC(=O)O)cc1 +COc1ccccc1-c1cn2c(-c3c(C)cc(C)cc3C)c(CN)c(C)nc2n1 +O=C(NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1)NC(Cn1cncn1)c1ccccc1 +O=c1[nH]c(N2CCOCC2)nc(NC2CNC2)c1-c1nc2ccccc2s1 +CCCCc1nc2c(N)nc3ccccc3c2n1Cc1cccc(CN)c1 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=S)N(C)C)CC2 +CCC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCCOC)c1=O +COc1ccc(CNC2CCC(C(=O)N3CCC(C(=O)N4CCCC4)(c4ccccc4)CC3)C(C)(C)C2)cc1 +c1cc2cc(-c3ccc(-c4cc5ccc(C6=NCCCN6)cc5[nH]4)cc3)[nH]c2cc1C1=NCCCN1 +O=C(Nc1ccncc1)Nc1ccc(-c2nc(N3CCOCC3)c3ccn(CCO)c3n2)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(C)c4ccc(S(C)(=O)=O)cc4)ncc23)ccn1 +CN(CCOc1ccc(F)cc1C(C)(C)C)C(=O)Nc1ccccc1C(=O)O +O=c1[nH]c(=O)n(CC(F)(F)c2ccccc2)nc1O +Cc1cnc(Cl)nc1-c1ccc(N(Cc2ccc(CNC(=O)C3CC3)cc2)C(=O)c2ccc(O)cc2O)cc1 +CC(C)Cc1sc(-c2cscn2)nc1C(=O)NCCCCC(=O)NO +Cn1c(=O)c2c(ccn2CC(=O)Nc2nc(-c3ccc(C(F)(F)F)c(F)c3)cs2)n(C)c1=O +COCCNc1nc(-c2ccc(OC)c(F)c2)cc2ncn(C)c(=O)c12 +O=C(O)COc1cccc2c1CCCC2CCC(=O)NN(c1ccccc1)c1ccccc1 +Cc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(OCc3ccccn3)nn1)CC2 +CCOC(=O)CNC(=O)Cc1ccc(Nc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 +CN(CCCN1CCOCC1)C(=O)c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1ccccc1OC)C(C)C +COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2N2CCC(O)C2)cn1 +O=C(NCC1(CO)COC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CC1CN(c2nc(N3CCOCC3)c3sc(C(C)O)cc3n2)CC(C)O1 +Cc1cccc(-c2nc(C(F)(F)F)cn2-c2ccc(S(N)(=O)=O)cc2)n1 +Cc1cccc(-c2nc(CCOc3ccc4c(c3)CCC4CC(=O)O)c(C)o2)c1 +CC(C)c1ccc(N2C(=O)C(=CN(C)C)SC2=S)cc1 +CN(C)CCCOc1cc(F)c(-c2c(Cl)nc(-c3ncccn3)nc2NCC(F)(F)F)c(F)c1 +C#CCn1c(=O)[nH]c2[nH]c(-c3ccccc3)nc2c1=O +OCc1cccc2c1Cc1c(-c3ccc(-c4ccc(O)cc4)cc3)n[nH]c1-2 +CC1(NC(N)=O)CCC2(C)CCC3(C)C(=CC(=O)C4C5(C)CCC(=O)NC(C)(C)C5CCC43C)C2C1 +CCOC(CN1CCN(CCc2ccc(C#N)c(OC)c2)CC1)c1ccc2c(c1C)COC2=O +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(F)cc2)CC1 +CC(NS(=O)(=O)c1ccc2c(Cl)cnc(N=C(N)N)c2c1)C(=O)O +CC(C)=C1c2ccccc2C=C(C2=CCN(C)CC2)c2ccccc21 +Cc1cc(C)cc(Sc2c(Cn3cnc(C)c3C#N)c(C)[nH]c(=O)c2I)c1 +CC(Nc1ccc(F)c(Cl)c1)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +Cc1ccccc1Nc1ncccc1C(=O)NCC(O)CN1CCN(c2ccccc2OC(C)C)CC1 +C=C(C)c1cccc(C(C)(C)NC(=O)Nc2ccc(Cl)c(C(=O)NC)c2)c1 +CC(C)C(=O)NCCCc1cccc2nc(-c3ccccc3)oc12 +NC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1NCc1cccc(C(F)(F)F)c1 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+CNC(C)C(=O)NC1CCC(NC(=O)Cc2ccccc2)CC2CCC(C(=O)NC3CCCc4ccccc43)N2C1=O +Cc1cc(Cc2ccc(Oc3ccccc3)cc2)n(O)c(=O)c1 +C=CCN(C)C(=O)NC1CCC(CNC(=O)c2ccccc2OC)(c2ccccc2)CC1 +CC(C)OC(=O)c1cnc(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)s3)CC2)c(Cl)c1 +COc1ccc(C(C)C)cc1-c1cc(F)cc(C(CC(=O)O)c2ncc(C)s2)c1 +O=C(NCCCCN1CCCC1)C1C(C(=O)NCc2nc(Br)cs2)C2C=CC1C21CC1 +O=C(c1ccc2[nH]c(=O)c3c(c2c1)CCSC3)N1CCN(C2CCCCC2)CC1 +COCCOc1ccc2nc(C3(NC(=O)CC(N)Cc4cc(F)c(F)cc4F)CCS(=O)(=O)CC3)sc2c1 +Cc1c(CC(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 +CC(C)CS(=O)(=O)NCc1nc2cnc3[nH]ccc3c2n1C1CCN(CCC#N)CC1 +COc1cccc(CNc2ncnc3c(C(N)=O)cccc23)c1 +CC(C)(C)CC(=O)NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1 +N#Cc1c(N)nc(-c2ccccc2O)c(F)c1C1CCCNC1 +CC(=O)N1CC2C(C1)C2c1cc(-c2cnc(N)c(C(F)(F)F)c2)nc(N2CC3CC2C3)n1 +Cc1ncc(C(=O)O)c(NCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)n1 +CC(CC(C(N)=O)C(CCC(F)(F)F)C(=O)NC1N=C(c2ccccc2)c2cccc(F)c2NC1=O)C(F)(F)F +Cc1ccc(C=CCN(C)Cc2ccc3c(c2)OCCC3)cc1 +CN1CCN(c2ccc(C(=O)Nc3cc(-c4cccc(NS(=O)(=O)c5ccccc5)c4)n[nH]3)cc2)CC1 +CCc1sc2ccccc2c1C(=O)c1cccc2ccccc12 +Cn1cc(-c2cnc(Nc3cccc(Cn4nc(-c5ccc(Cl)c(C(F)(F)F)c5)ccc4=O)c3)nc2)cn1 +Cc1cc(NC(CCCCNCc2ccc(Cl)cc2)C(=O)NO)ccc1F +O=C(NC1CCC(CCN2CCN(c3nsc4ccccc34)CC2)CC1)c1cccnc1 +COc1cc(CN2CCCC23COC3)ccc1OC1CN(C(=O)c2nnc(-c3ccc(C(F)F)cc3)o2)C1 +Oc1ccc2c(c1)C1CCCN(Cc3ccccc3)C1CC2 +CSc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1ccccc1 +FC(F)c1nnc(N2CCN(c3ncnc4sc(CC(F)(F)F)cc34)CC2)s1 +COc1ccc(-n2nc(C(F)(F)F)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)cc1 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(-c4ccccc4CN4CCC(O)C4)cc2)CC3)cc1 +O=C(NCCC(c1ccccc1)c1ccccc1)C1SC(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C(O)C1O +CC(O)C(COCCc1ccccc1)n1cnc2c(N)ncnc21 +O=c1cc2n(-c3ccccc3)nc(-c3ccccc3)nc-2cc1N1CCCC1 +C=CCc1ccc2c(c1O)-c1cccc3c1C(C2)N(CCC)CC3 +CN1C(=O)NCc2c(NC(=O)NC3CC(C)(C)Oc4c3ccc(F)c4Cl)cccc21 +CCCCCCCCC(O)c1ccc2ccc(CC(O)c3cccc(C(=O)O)c3)nc2c1 +Oc1nc2cc(Cl)ccc2n1C1CCN(CC2COc3ccccc3O2)CC1 +COc1cccc(C=CC(=O)N2CC(CCl)c3c2cc(N)c2ccccc32)c1 +CCCc1nc2cc3ccccc3cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 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+O=C(Nc1ccc(Cl)cc1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CCC(=O)c1ccc(OCCCCOc2ccc(C(=O)O)cc2OC)c(C)c1O +COC(=O)C1C(C=Nc2ccccc2)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +CCC(N)C(=O)NC1C(=O)N2C(CCC1CNC(C)=O)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +CCCCCn1cc(NC(=O)C2CCCCC2)c(=O)cc1-c1ccccc1 +CCNc1nc(C)c2cc(-c3ccc(O)c(OC)c3)c(=O)n(C3CCCC3)c2n1 +CCS(=O)(=O)Nc1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)cc2OCC(C)C)c1 +O=S(=O)(Cc1ccc2c(c1)CCNCC2)c1ccc(-c2ccc(Cl)cc2)cc1 +Cc1ccc(-c2ccc3c(c2)N(c2nc4c(s2)C(=O)NC(C)(C)C4)CCO3)nn1 +CCNc1nc2ccc(OC)cc2cc1Cc1c(=O)[nH]c(COC)c2cc(OC)c(OC)cc12 +N#Cc1ccc(Nc2nc(N)nc(Cc3ccc(Cl)cc3Cl)n2)cc1 +Cc1ccc2c(c1)C(C(=O)Nc1ccccc1C(C)C)c1ccccc1CO2 +Cc1cccc2scc(Cn3c(=O)n(CCC(=O)O)c4ccccc43)c12 +O=C(Nc1cccc(Cl)c1)OCc1ccc(Cc2c[nH]cn2)cc1 +CN(C)CCCNC(=O)c1csc2nc(-c3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)cn12 +CCCCCCCCCC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC1C=CCCNC(=O)C=CC(C(C)C)NC1=O +Cn1cc(-c2cc3c(-c4ccc(Br)c(N5CCCC(O)C5)n4)n[nH]c3cn2)cn1 +C=C(c1ccccc1)C12CCCC1CC(CCCCCCCC)=C2c1ccccc1 +CC1CC(Nc2nc(N3CCOCC3)[nH]c(=O)c2-c2nc3ccccc3s2)C(O)C1O +NC(=O)c1nn(-c2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)c2ccccc12 +Cc1noc2c1C(=O)CC(CN1CCC(C(=O)c3ccc(F)cc3)CC1)C2 +O=C(c1csc2ccccc12)N(CCc1ccc(Cl)cc1)C1CCC2(CCCO2)CC1 +O=CN(O)C1(CS(=O)(=O)N2CCN(c3ccc(F)cc3)CC2)CCC1 +CCc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(CCc3cnc[nH]3)[nH]c(=O)c12 +Cc1ccc(CNc2nc(C#N)nc3c2ncn3Cc2ccccc2)cc1 +COc1ccc2c(c1)c(NCCCCN)c1c3ccccc3nc-1n2C +CS(=O)(=O)Nc1cnccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 +COCCCOc1cncc(C2NC(=S)NC3=C2C(=O)c2ccccc23)c1 +NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)c(F)c2)cn1 +CCc1ncnc(-c2ccc(C(=O)N3CC(C)NC(C)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCN(C)Cc1cccc(C=C2Oc3cc(OC)c(OC)cc3C2=O)c1 +[N-]=[N+]=NCCc1c(C(=O)NCCc2ccc(N3CCCCC3)cc2)[nH]c2ccc(Cl)cc12 +CC(=O)Nc1ccc(Nc2nc3c(c(Nc4ccccc4S(=O)(=O)NC(C)C)n2)CCN3)cc1 +Cc1cccc(Cn2cc(C(=O)NC3C4(C)CCC(C4)C3(C)C)c(=O)c3ccc(F)cc32)c1 +COc1cc(OC)c(C=C2CNCC(=Cc3c(OC)cc(OC)cc3OC)C2=O)c(OC)c1 +CN(C)CCOc1nc2cccnc2nc1C#Cc1cccc(F)c1 +O=C1c2ccccc2C(=O)N1CCCCN1CCN(c2ccccc2)CC1 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+Fc1ccc(C2CCN(c3ccn4c(CC5CC5)nnc4c3Cl)CC2)c(F)c1 +CCCCS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1 +CC#CCOc1ccc(S(=O)(=O)C(C(=O)NO)C2CCSCC2)cc1 +Nc1ccccc1NC(=O)c1ccc(C2CCN(Cc3ccccc3)CC2)cc1 +CN(C)CCN1CCN(C(=O)C2CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC2)CC1 +CCN(CC)CCCN=C(c1cccnc1)N(CCCN(CC)CC)c1ccnc2cc(Cl)ccc12 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(C(=O)NCCO)nc3)cc12 +CN1CCC(C(c2ccccc2)N2CCN(C(=O)CC(c3ccccc3)c3ccccc3)CC2)CC1 +Cn1cc(-c2ccc(Cl)cc2)c(Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)n1 +O=C(Cn1c(=O)n(-c2ccccn2)c2ccccc21)Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ccccc21 +COc1ccc2cc(C(=O)C3CC3)cc(CCNC(C)=O)c2c1 +CC1NC(=O)C(c2ccc(F)cc2)=C1c1cc(F)c2c(c1)NC(=O)CO2 +CCC(NC(=O)C1CCCCN1CCOc1ccccc1)c1ccc(C(=O)O)cc1 +Cc1c(C(=O)NCCC2CCN(C)C2)sc2ncnc(Nc3ccc(F)cc3OC(C)CF)c12 +COc1cc(-c2cc(F)cc(F)c2F)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +O=c1[nH]c(N2CCN(c3cnccn3)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +CC(C)C1NC(=O)C(Cc2ccc(Cl)cc2)NCCOc2ccccc2CCCNC(=O)C(CN(C)C)NC1=O +COc1ccccc1N1CCN(CCc2ccc3nc[nH]c3c2)CC1 +Fc1ccc(-c2nnc3ccc(N4CCCCCC4)nn23)cc1 +CCNc1n[nH]c2cc(NC(=O)NCc3cccc(F)c3)ncc12 +CCc1nc(C(N)=O)c(Nc2ccc(N3CCN(C)CC3)cc2)nc1NC1CCC(O)CC1 +Cc1cc(C)cc(NC(=O)Nc2ccc3c(c2)CCc2sc4ncnc(N)c4c2-3)c1 +COc1cncc(-c2ccc3[nH]nc(C(=O)NCC4CCN(CC(=O)O)CC4)c3c2)c1 +CCN(CC)C(=O)c1ccc(C(=C2CCNCC2)c2ccccc2)cc1 +CN(c1nc2ccccc2s1)C1CCN(CCCCOc2ccccc2)C1 +Oc1cc(NCCCNC2CCNc3c(Cl)cc(Br)cc32)nc2ccccc12 +O=C(NO)C1C(c2ccccc2)C1c1cccc(-c2ncc(F)cn2)c1 +CC1CCN(c2cc(N3CCN(C)CC3)cnc2NC(=O)c2ccc(C#N)o2)CC1 +O=C1Nc2ccccc2C12CC2c1ccc2c(C=Cc3ccc(CN4CCOCC4)cc3)n[nH]c2c1 +COc1ccc(COC(=O)C2=C(C)NC(=S)NC2c2ccccc2)cc1 +CCCN(CCC)C(=O)Cc1c(-c2ccc([N+](=O)[O-])cc2)nc2c(Cl)cc(Cl)cn12 +O=[N+]([O-])c1cn2c(n1)OCC(Oc1ccc(OC(F)(F)F)cc1)C2 +FC(F)(F)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 +O=C1COc2ccc(CN3CCN(c4ccc(Cl)cc4)CC3)cc2N1 +CC1CCCCC1Oc1nc(N)c2c(=O)ccn(C3CCCCC3O)c2n1 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3C(=O)OC(C)(C)C)c1C +COc1ccc2ccc(CCc3c(C(=O)O)[nH]c(=O)[nH]c3=O)cc2c1 +CCOC(=O)CNC(=O)CCc1coc2cc(Cl)c(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc43)cc12 +N#Cc1cc(Cn2cncn2)ccc1-c1ccc(O)c(Cl)c1 +Cc1cn(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2F)cn1 +COC(=O)Nc1nc2ccc(C(=O)c3ccccc3C(=O)Nc3cccc(F)c3)cc2[nH]1 +CC(=O)N1CCC(OCc2cncc(-c3cnc4c(c3)CCCN4C(C)=O)c2Cl)CC1 +CC(=O)SCC(C)C(=O)N(CC(=O)O)C1Cc2ccccc2C1 +CNC(=O)c1ccc(C(=O)Oc2ccc(S(=O)(=O)C3(C(=O)NO)CCC4(CCNCC4)C3)cc2)cc1 +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(OCCO)c2c(CO)n1)c1ccccc1 +CCCCC1=NN(C(=O)NC2CC3CCC2(C)C3(C)C)C(C)(C)C1c1ccccc1 +Cc1csc(-c2nc(CCCCC(=O)Nc3ccccc3)[nH]c2-c2ccc3c(c2)OCO3)n1 +Cc1nc2ccc(C(F)(F)F)nc2n2c(-c3cc(O)ccc3Cl)nnc12 +CCNC(=O)c1ccc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4ccccc4O)cc32)cc1C +O=c1[nH]c(SCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2sc3c(c12)CCCC3 +CCCCCCCCCCCCCCCCn1c(O)nc2c(=O)[nH]c(=O)[nH]c21 +Cn1cc(-c2ccc(N3CCC(n4ncc5cc(F)ccc54)CC3)nn2)cn1 +CCCCc1nnc(SCc2cccc(OC)c2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +COc1cc(Br)c2c(c1)OCCN2c1nc(Cl)cn(C(C)C2CC2)c1=O +N=C(N)NCCC(=O)NCC1(Nc2ccccc2)CCN(Cc2ccccc2)CC1 +N#Cc1ccccc1N1CC2C(C1)C2NCC(=O)N1CC(F)CC1C#N +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1c[n+]([O-])c(CNC(=O)OC(C)(C)C)cc1c2C +NS(=O)(=O)c1ccc2nc(-n3cc(C=NO)c(-c4ccc([N+](=O)[O-])cc4)n3)sc2c1 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)N1CCN(c2ccc(Cl)cc2)CC1 +CN1CCN(C(=O)NC2CCN(Cc3ccn(-c4ccc(C(F)(F)F)cc4)c3)CC2)C(c2ccccc2)C1 +CC(C)Nc1nc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc2[nH]1 +N#Cc1ccnc(Nc2nccc3nc(-c4c(Cl)cccc4Cl)[nH]c23)c1 +COc1cc(C(=O)C=C2c3ccccc3C(=O)c3ccccc32)cc(OC)c1OC +Cc1ccccc1-c1nc(C(=O)Nc2cccc(C(=O)O)c2)c(CCC2CCCCC2)[nH]1 +Cc1ccc2c(N3CCN(Cc4ccc5c(c4)NC(=O)CO5)CC3)cccc2n1 +O=C(Cc1ccc(Cl)cc1)NC(Cc1ccc(Cl)cc1)C(=O)NC1CCC(O)CC1 +COc1c(NC(=O)c2ccc(NS(C)(=O)=O)cc2)cc(-c2ccc[nH]c2=O)cc1C(C)(C)C +Cc1cc(-c2cncs2)cc2c(NC3CCOCC3)cc(=O)n(C)c12 +Cc1nnc(-c2cccc(CN3CCN(C(=O)c4ccc(CC5CCC(C(O)c6ccccc6)N5)cc4)CC3)n2)o1 +CCC(C)C(CN1CCCC1)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +Cc1ccc(CN2CCC(O)C(N3CCC(c4ccccc4)CC3)C2)cc1 +O=C(C=Cc1ccc(Cl)c(Cl)c1)N1CCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1cccc(C(=O)N2CC(C)OCC2Cc2cc(-n3nccn3)ccc2F)c1-n1nccn1 +CCN(CCOC)c1nc(C)nc(N(CC)c2c(C)cc(C)cc2C)n1 +Cc1cncc(-c2nc(C(F)(F)F)cn2-c2ccc(S(N)(=O)=O)cc2)c1 +CC(C)C(CO)Nc1ccc2ncc(-c3cccnc3)n2n1 +CC(C)c1cccc(C(C)C)c1NC(=O)N(Cc1ccccc1)C(C)c1nc2ccccc2c(=O)n1-c1ccccc1 +CC1(C)CCCC(Oc2cc(F)c(C(=O)NS(C)(=O)=O)cc2Cl)C1 +Cn1cc(-c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cn1 +CC(NC(=O)Nc1cccc(-c2nnnn2C)c1)C(O)CN(C)C(C)C(O)c1ccccc1 +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1cc(F)cc(F)c1 +CCCCOc1ccc(-c2c(F)ccc(C(=O)O)c2F)cc1CNC(=O)c1ccc(C(F)(F)F)cc1F +Cc1c(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CCO2)ccc2c1COC2=O +O=C(O)COc1ccc(OCc2cc(-c3ccc(C(F)(F)F)cc3)cc(-c3ccc(C(F)(F)F)cc3)c2)cc1 +O=C(O)c1cn(C2CC2)c2c(OC(F)F)c(N3CCN(c4ccc(F)cc4)CC3)c(F)cc2c1=O +CCCCCC(=O)OCC1(CCl)OC(n2ccc(N)nc2=O)C(F)C1OC(=O)CCCCC +CC(C)C(NS(=O)(=O)c1ccc(-c2ccccc2)cc1)C(=O)O +CCn1cnc(-c2cc3nccc(Oc4ccc(NC(=O)CC(=O)Nc5ccccc5OC)cc4F)c3s2)c1 +CNC(=O)C12CC1C(n1cnc3c(C=C(O)c4ccccc4Cl)nc(C#Cc4ccccc4Cl)nc31)C(O)C2O +Cc1cc(OCCNc2ccncc2)cc(OS(=O)(=O)c2ccccc2[N+](=O)[O-])c1 +CN1CCN(C2Cc3ccccc3Sc3ccc(-c4nnnn4C)cc32)CC1 +OCC(O)CN1CC=C(c2[nH]c3nccc4c3c2COc2ccc(F)cc2-4)CC1 +CNS(=O)(=O)Nc1cccc(Cc2c(C)c3ccc(OC(=O)N(C)C)cc3oc2=O)n1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NC(C)C(=O)NCc3ccco3)[nH]c3ccc(Cl)cc23)c1 +C#CCN(Cc1cc2c(O)nc(C)nc2cc1C)c1ccc(C(=O)NC(CSc2nn[nH]n2)C(=O)O)c(F)c1 +COC1C(CO)OC(n2c3ccc(Br)cc3c3c4c(c5c6cc(Br)ccc6[nH]c5c32)C(=O)NC4=O)C(O)C1O +COc1ccc(-c2ssc(=NO)c2-c2cc(OC)c(OC)c(OC)c2)cc1N +c1ccc(-c2ccc(-c3c[nH]c(C4Cc5c([nH]c6ccccc56)C(C5CCOCC5)N4)n3)cc2)cc1 +O=C1NCN(c2ccccc2)C12CCN(C1CCCc3ccc(Cl)cc31)CC2 +Nc1ncc2c(-c3cnn(C4CCNCC4)c3)coc2c1OCc1c(Cl)ccc(F)c1Cl +CS(=O)(=O)c1cccc(C=CC(=O)NC2CCC(CCN3CCc4cc(C#N)ccc4C3)CC2)c1 +CN1CCN(Cc2ccc(C(=O)NN(CC3CCCO3)c3nc(C#N)ncc3Br)cc2)CC1 +O=C(CCCCCCCSc1nc(O)cc(Cc2ccccc2)n1)NO +NS(=O)(=O)c1ccc(NC(=O)C=Cc2ccc(OC(F)(F)F)cc2)cc1 +COP(=O)(Nc1ccc(-c2cc3ccc(OS(N)(=O)=O)cc3oc2=O)cc1)OC +Oc1ccc2c(c1)C(c1ccc(OCCN3CCCCC3)cc1)c1c-2ccc2cc(O)ccc12 +CCCCCCN(C(=O)N1CCOCC1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CC(C)CCNC(=O)c1ccc(C#Cc2ccccc2)nc1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccc(OCC(=O)O)cc1 +CC1C2Cc3cc4nc(O)[nH]c4cc3C1(C)CCN2CC1CC1 +CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CC(C)(N)C3)c2c1Cl +Cc1cc(C)cc(C(CC(C)C)NC(=O)c2cc(COc3cccc(F)c3)ccc2CCC(=O)O)c1 +N#Cc1c(C=Cc2ccccc2)[nH]c2nc(N)[nH]c(=O)c12 +CN(C(=O)c1cc2c(s1)-c1ccccc1OC2)c1ccccc1Cl +CCC(C)C(N=C(S)Nc1ccccc1)C(=O)NC(C=O)Cc1c[nH]c2ccccc12 +O=C1C(=O)N(CNc2ccc(Br)cc2)c2ccccc21 +COC(=O)N(CC(=O)O)Cc1cc(OCc2nc(-c3ccc(F)cc3)oc2C)ccc1F +Brc1cccc2c1[nH]c1c[n+](Cc3ccc4ccccc4c3)ccc12 +Nc1nc(-c2ccccn2)c(-c2ccnc3ccccc23)s1 +CCCS(=O)(=O)Nc1cccc(-c2nn(C(C)C)cc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +CC12CCC(=O)C=C1CCC1C2CCC2(C)C(C3N=CC=N3)CCC12 +CN(CCCCNC(=O)c1cc2ccccc2[nH]1)C1Cc2cccc3[nH]c(=O)n(c23)C1 +Nc1ncnc2c1sc1cc(-c3cccc(C(=O)O)c3)ccc12 +CNc1nc(N)nc2nc(-c3ccccc3C(F)(F)F)ccc12 +O=C1OC2(CCN(c3nc4c(Cl)cccc4[nH]3)CC2)c2ccccc21 +N=C(N)c1ccc2oc(-c3cccc(OCCCOc4ccccc4)c3)cc2c1 +O=C(NCc1cc[nH]c1)C(=O)c1c[nH]c2ccc([N+](=O)[O-])cc12 +CCOC(=O)c1ncn2c1Cn1cnnc1-c1cc(O)ccc1-2 +Cc1cnccc1-c1nc(C)c2c(C)nc3c(F)cc(OCC(F)(F)F)cc3n12 +COc1ccc(CNC(=O)c2cc(-c3cncc(C)c3)nnc2-c2ccccc2)nc1OC +CCON1CCC(Nc2ncc(C(=O)NO)cn2)(c2ccccc2)CC1 +c1ccc(OCCCN2CCN(c3cccc4ccoc34)CC2)cc1 +O=C(c1ccc2c(c1)ncn2-c1cccc(C(F)(F)F)c1)N1CCCCC1 +C1=C(Cc2ccccc2)CCN(CCC(c2csc3ccccc23)N2CCOCC2)C1 +CCCC(C)n1ccnc1C=CC=CC(=O)C=Cc1nc2ccccc2n1C(C)CCC +O=C(O)Cc1ccc(-c2ccc(NC(=O)c3cccc(-c4ccc(O)c(O)c4O)c3)cc2)s1 +COc1ccccc1CN(C(C)=O)c1cnccc1Oc1ccccc1 +CC(=O)N1CCc2c(C(=O)N3CCC(c4cccc(F)c4C(F)(F)F)CC3)n[nH]c2C1 +CNC(=C[N+](=O)[O-])Nc1cccc(-c2csc(N=C(N)N)n2)c1 +O=C(O)c1cc(-c2ccc(C(O)C(F)F)cc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1 +COc1cc2c(cc1OCCN1CCCCC1)C(=O)C(=Cc1ccncc1)C2 +COCCOc1ccc(CN(C)C(=O)c2ccc(S(=O)(=O)Nc3ccccc3)cc2)cc1 +NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3Cl)ccc2Cl)n(-c2ccccc2)n1 +O=C(CCN1CC=C(c2ccc(Cl)cc2)CC1)c1ccccc1 +CCCN(CCC)Cc1cn(-c2cc(NC(=S)NCC)ncn2)cn1 +FC(F)(F)c1cccc(CCNC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)c1 +CC(C)(C)c1ccc(Cn2nc(-c3ccc(Cl)cc3)cc2C(=O)NN=Cc2cccc(O)c2O)cc1 +Cn1c(N2CCC(F)(F)CC2)cc(OCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O +CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4nc5ccccc5[nH]4)cc3)nc2n(CCCOC)c1=O +C=CC=CC(C)C(O)C(C)C(O)C(C)CC(C)=CC(C)C(O)C(C)C=CC(O)CC1OC(=O)C(C)C(O)C1C +COc1cc(-c2ccc[nH]2)c2c3c(ccc(F)c13)NC2=O +N#Cc1ccc(C(C(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c2cccnc2)cc1 +Cc1nn(-c2cncc(C(C)(C)O)c2)c2ccccc12 +O=[N+]([O-])c1cc2cn[nH]c2c2c1[nH]c1ccc(Cl)cc12 +Cc1ccc(-c2ccccc2C(=O)N2CC3CN(c4cnc5ccccc5n4)CC3C2)cc1 +O=C1CCCN1CCCCN1CCN(c2ccc(F)cc2F)CC1 +CCc1nc(C(F)(F)F)cnc1NC1CCCC1NC(=O)c1cc(F)ccc1-c1ncccn1 +N#Cc1cc(-c2ccnc(Nc3ccc(C(=O)NCCO)cc3)n2)cnc1N1CCC(F)C1 +CN(C)CCNc1ncc(C(N)=O)c(Nc2cccc(C(F)(F)F)c2)n1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(ncnc2-c2ccc[nH]2)C1 +COc1ccc2occ(C(=O)Nc3cccc(Cl)c3)c(=O)c2c1 +O=P(Oc1ccccc1)(Oc1ccccc1)OC1C=CS(=O)(=O)C1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCCF +CN(CC(=O)NC(CCCCN)C(=O)C(=O)NCCN1CCOCC1)C(=O)c1ccccc1Sc1ccccc1C#N 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+c1cc(-c2cncc(NCC3CCOCC3)n2)c2cc(C3CCNCC3)[nH]c2n1 +COCC1CCCN1c1cccc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)n1 +CN(C(=O)c1ccccc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +COC(=O)c1ccc(Nc2nnc(SCc3ccccc3C)[nH]2)cc1 +O=c1cc(NC2CCN(Cc3ccc4ccccc4c3)CC2)c2cc(Cl)ccc2o1 +O=C(O)Cc1ccc(-c2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)cc1 +CSCC(NCc1c[nH]c2c(=O)[nH]cnc12)C(O)CO +CC(=NNC(=O)c1cc(Br)ccc1O)c1cc2cc(Br)ccc2n1C +CCC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)n1ccnc(NCC2COc3ccccc3O2)c1=O +N#Cc1ncc(C2=CCC(N(CCN3CCCC3)C(=O)Nc3ccc(F)c(Cl)c3)CC2)s1 +Cc1cc(C)cc(-c2[nH]c3ccc(C(C)(C)C(=O)N4CCCCC4)cc3c2CCNCCCCc2ccncc2)c1 +CN(C)c1ccccc1N1CCN(Cc2ccc(F)cc2Cl)C(=O)C1=O +CC(C)c1nc(CN2CCC(OC3CCC(Oc4cnc(S(C)(=O)=O)cn4)CC3)CC2)no1 +CC(c1ccccn1)n1[nH]c(=O)c2nc3cc(Cl)ccc3c(O)c2c1=O +CCC(Nc1cc(CN2CC(C(=O)O)C2)ccn1)c1ccc(Cl)c(C)c1 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1ccc(C#N)cc1 +O=Cc1cc(O)cc2ccc(-c3ccc(O)c(F)c3)cc12 +Cc1cccnc1C(=O)Nc1cnn2ccc(N3CCCC3c3cccc(F)c3)nc12 +CC(C)c1n[nH]c2cc(OCCNCC(O)c3cccc(NS(C)(=O)=O)c3)ccc12 +CCn1cnc2c(-c3ccc(F)c(-c4ccc(S(C)(=O)=O)cc4F)c3)cnnc21 +CC1CN(c2ccccc2Cl)C(=O)c2cc(COc3ccc(F)cn3)nn21 +COc1ccc(CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)c(OC)c1 +O=C1N(c2ccc(C3CCC(N4CCCC4)CC3)cc2F)CCC12CCNCC2 +CC(NC(CCc1ccccc1)C(=O)O)C(=O)N1CC(NC(=O)C(CS)Cc2ccccc2)CC1C(=O)O +Cc1cc(Oc2ncccc2N2CC(F)(F)C2)ccc1-c1c(C)c(=O)[nH]c(=O)n1C +O=C(OCc1ccc(Cl)c(Cl)c1)C1(c2ccc(I)cc2)CCNCC1 +COc1cc(Nc2ncc3ccn(-c4cccc(C(=O)NCCNC(C)=O)c4)c3n2)cc(OC)c1OC +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccc(C(F)(F)F)cc4)ncc23)ccn1 +CC(=O)c1cn(CC(=O)N2C(C(=O)Nc3cccc(Br)n3)CC3CC32)c2nnccc12 +CC(C)C(O)(c1ccc2cc3c(cc2c1)CN(C)C3=O)c1c[nH]cn1 +CC(C)=CCCC(C)CC(=O)OCC1=C2C(=CC3(C)CCC(O)(O3)C(C)CC2O)OC1=O +N#Cc1cnn2c3cc(nc12)N1CC(CC1CO)OCC=CCOc1cccc(c1)N3 +COc1ccc(-c2cc(-c3c(OC)cc(OC)c(C4CCN(C)C4CO)c3O)n[nH]2)c(OC)c1 +CC(=O)Oc1ccc(C(=O)C=Cc2ccc3c(ccn3C)c2)c2c1C=CC(C)(C)O2 +Cn1cncc1CN1CC(N(CC2CCN(C(=O)C(C)(C)C)CC2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21 +NC(=NCCC(c1cccc(N)c1)c1ccccn1)NCCCc1c[nH]cn1 +Cc1ccc(CN2CCC(N3CCC(c4ccc(O)cc4)CC3)C2=O)cc1C 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+COc1cc(C(=O)N2CCN(C)CC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)c2nc[nH]c2c1C(N)=O +N#Cc1ccc(N2C(=O)C3C(O)CCN3C2=O)c2ncccc12 +CC(C)Sc1nc2c(c(Nc3ccc4c(c3)N(C)CCC4(C)C)n1)CCN(c1ncccc1C(F)(F)F)CC2 +CCSc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2noc(S)n2)cc1 +O=C(NC1CCC(O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1Cl +O=C(O)C(O)=CC(=O)c1cc(Cc2ccccc2F)cn(Cc2cccc(F)c2F)c1=O +CCC(N)C(=O)NC1C(=O)N2C(CCC1CCN)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +O=C(c1ccccc1)N1CCC2(CC1)CCN(C(=O)N1CCN(C3CCC3)CC1)C2 +CC(C)(N)C=C(C#N)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cccc(F)c3)cc2F)c2c(N)ncnc21 +Cc1ccc(Cn2c(C3CNCCO3)nc3ccccc32)cc1C +Cc1ccc(OCC(=O)Nc2ccc3c(c2)OCO3)c(C)c1 +Cc1nc(-c2ccc(Cl)cn2)nc(NCC(NCCCCCc2ccccc2)c2ccccc2)c1Cl +O=C(O)c1cccc(NC(=O)C2NC3(CCCCC3)C3(C(=O)Nc4cc(Cl)ccc43)C2c2cccc(Cl)c2F)c1 +O=c1ccc2cnc(Nc3ccc(N4CCOCC4)cc3)nc2n1C1CCCC1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4ccc(NC5CCOCC5)nn4)ccn23)c1 +CN1CCc2ccc(Nc3nnc(-c4cccc(-c5cccnc5)c4)o3)cc2C1 +COc1ccc2c(c1)COc1cc(Nc3ccccc3N)ccc1C2=O +NC(=O)C(NC(=O)c1ccc(C2CC2)c(OCC(F)(F)F)n1)c1ccccc1 +CC(C)(C)c1nc(N2CCN(CCCCNC(=O)c3cn4ccncc4n3)CC2)cc(C(F)(F)F)n1 +CC(C)c1c(Cc2c(F)cccc2F)nc(SCC(=O)c2ccccc2)[nH]c1=O +NC1(CNC(=O)c2ccc(F)cc2)CCN(c2ncnc3[nH]cc(Cl)c23)C1 +Nc1nc(C(F)(F)F)cc2c1[nH]c(=O)n2Cc1ccc(NCCN2CCCC2)nc1 +CCN(CC)C(=O)Cn1c(=O)c(C(=O)NC)c(O)c2ncc(Cc3ccc(F)cc3)cc21 +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc(Cl)c(Oc2cccc(NC(=O)C(C#N)=Cc3cnc[nH]3)c2)n1 +CN1CCN(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)CC1 +COC1Cc2c(csc2-c2cccnc2)C2(CCN(Cc3ccccc3)CC2)O1 +N#Cc1ccc(OCc2ccc3c(c2)OCO3)cc1OC(C(=O)O)c1ccccc1C(F)(F)F +O=S(=O)(c1ccc(Cl)cc1)c1snnc1-c1ccccc1 +CCCCCCCCCCCCn1nnc(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccc(OC)cc2)n1 +CC(C)c1nc2ccccc2n1Cc1ccc(C(=O)NC2CC3(CCCO3)CC2C(=O)NO)cc1 +COc1cc(CC(C)C(=O)N2CCN(c3ccc(C(F)(F)F)cc3C(N)CC(C)C)CC2)ccc1Cl +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cc(CO)c(F)c4[nH]nc(N)c34)cc2)c1 +Nc1ccc(C(=O)N2CCC(N3CCCCC3)CC2)cc1Cl +CC(NC(=O)Nc1cc2[nH]nc(-c3ccc(C#N)cc3)c2cn1)c1ccc(F)cc1 +CCc1c(-c2ccccc2-c2cccc(OCC(=O)O)c2)oc(-c2ccccc2)c1-c1ccccc1 +CCCCCCc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 +Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C4CC4)cc3)ccc2N2CCN(C)CC2)c1Cl +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)OC2CC3OCCOC3C2)cc1 +CCCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=[N+]([O-])c1c(Nc2ccccn2)cc(Cl)c2nonc12 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C)CC3C)c(F)c2)c1C#Cc1ccc(N)nc1 +Cn1cc(C2=C(c3coc4cc(F)c(F)cc34)C(=O)NC2=O)c2ccc3ccccc3c21 +COc1cc(Br)c(S(=O)(=O)Nc2ccc(C(F)(F)F)c(OCC3CCCN3C)c2)cc1OC +O=C(C(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1ccc(Cl)cc1)N1CCCCC1 +CC1(C)Oc2ncnc(N)c2N=C1c1ccc(C23CCC(C(=O)O)(CC2)CC3)cc1 +O=c1[nH]c2c(O)ccc(C(O)CNCCCSCCOCCc3cccc4ccccc34)c2s1 +CC(CO)NC(=O)c1cccc(-c2cc(Nc3cccc(N4CCCC4C)n3)c3nccn3n2)c1 +CN1CCC(N2CC(c3ccccc3)(c3ccccc3)NC2=O)CC1 +O=C(Nc1ccc(C=Cc2ccc(NC(=O)C3CCCN3C(O)C3CCCCC3)cc2)cc1)C1CCCN1C(O)C1CCCCC1 +CCN(CC)C(=O)c1ccc(N(c2cccc(OC)c2)C2CCN(CC3CC3)CC2C)cc1 +OC(CNCc1ccccc1OCc1ccccc1)c1cccc(Cl)c1 +Cc1cc(CN2CCN(c3c(Br)cnc4[nH]c(-c5ccc(OCCO)cc5)nc34)CC2)no1 +Cc1cc2cc3c(cc2[nH]1)NC(=O)C(C)CCCC(N1CCC(c2c(F)ccc(Cl)c2F)=CC1=O)c1cc-3ccn1 +CCCC(=O)NC1CCN(c2cccc3oc(CCCCc4ccccc4)cc23)C1 +Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NC(C)C)cn1 +Nc1nc(-c2ccco2)c2cnn(CCCc3ccccc3)c2n1 +CCS(=O)(=O)c1ccc2[nH]c(-c3cccc(-c4ccccc4)c3F)nc2c1 +N#Cc1ccc2cc1Oc1ccc3cccc(c3c1)C(=O)NCCNC(=O)Cc1cncn1C2 +OC1CCC(OCc2ccc(F)cc2)CC1N1CCN(c2ccccc2)CC1 +Clc1ccc2c(NCCn3cnc4c(N5CCN(c6ccccc6)CC5)nc(Cl)nc43)ccnc2c1 +CC(=O)NC(CCCCN)C(=O)Nc1ccc(C(=O)NC(CC(=O)O)C(=O)O)cc1 +O=C(c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3CCc2ccccc2)cc1)N1CCCC1 +O=C(C=Cc1ccc(I)cc1)Nc1ccc2c(c1)OCCO2 +Cc1ccc(NC(=O)c2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1Nc1nccc(-c2cncnc2)n1 +CCCCC1c2c(nc3c(c2N)CCCC3)Oc2c1c(=O)oc1ccccc21 +Cc1nc(NC(=O)N2CCCC2C(N)=O)sc1-c1ccnc(C2CCC2)n1 +CCCCCCCN=C(N)Cc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +O=C1OC2(CCC(C(=O)Nc3ccn(-c4ccccc4)n3)CC2)c2cnccc21 +CCC(CO)Nc1nc(NCc2ccccc2)c2c(n1)N(C(C)C)CN2 +COc1cc2c(ccn2-c2cccc3c2ccn3C)c(OC)c1OC +CCOC(=O)Cc1ccc(NC(=O)c2cc(C#N)c[nH]2)c(C2=CCC(C)(C)CC2)n1 +CCC(NC(=O)c1c(OCCO)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +Cc1ccc(N2CCN(CCCCOc3ccc4c(=O)cc(-c5ccc(Cl)cc5)oc4c3)CC2)cc1 +CC(O)C(CCCc1ccccc1)n1cnc2c(N)ncnc21 +O=C(CC1CC1)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +CC1(c2cc(NC(=O)c3cnc(C(F)F)cn3)cc(Cl)c2F)CC(C(F)(F)F)OC(N)=N1 +C=CC(=O)N1CC(N2C=C(C#Cc3cc(OC)cc(OC)c3)C3C(N)=NC=NC32)C1 +Cc1ccc(NC(=O)c2cnoc2C)cc1C(=O)Nc1cnc(Nc2ccc(N3CCN(C)CC3)cc2)nc1 +CCOc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)ccc1C +O=C(CCCN1C(=O)c2ccccc2C1=O)N1CCCCCC1 +C#CCN(Cc1cc2c(=O)n(C)c(CO)nc2cc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +CN(C)C(=O)Cn1cc(-c2nc(C3(c4ccc(-c5cnc(N)cn5)nc4)CCC3)no2)cn1 +CCCCCCc1nc2cc(C=CC(=O)NO)ccn2c1NCCC(=O)NCC(C)(C)CN(C)C +Cc1nc(NC(C)C(Cc2ccc(Cl)cc2)c2cccc(Br)c2)cc(N(C)C)n1 +Cc1ccncc1Oc1ncnc(OC2CCN(C(=O)OC(C)C)CC2)c1C +CN(Cc1ccccc1)C(=O)c1nc(-c2ccccc2F)c2ccccc2n1 +FC(F)(F)c1nc2c(c(NCc3ccc(-c4ccccc4-c4nn[nH]n4)cc3)n1)CCCC2 +CCCOc1cnc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c(Cl)c1 +Cc1cc(-c2n[nH]c3c2CN(C(=O)NC2CCCN(Cc4c(C)cccc4C)C2)CC3)ccn1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c(Cl)c1 +CCCc1cccc(-c2cc(NC(=O)C3CC(=O)NC3C)nn2-c2ccccc2)c1 +O=C(Nc1ccc(Nc2ncnc3cc(OCCCN4CCN(CCO)CC4)ccc23)cc1)NC1CCCCC1 +CCCCCN=c1ccn(-c2ccc3ccccc3c2)c2cc(Cl)ccc12 +CCCCC12CC1(COC(C)=O)C(=O)Nc1ccc(Cl)cc12 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCOc1ccc(C(=O)N3CCCC3)cc1)C2 +COc1cccc(NC(=O)c2ccc(NCCCN3CC(C)CC(C)C3)c([N+](=O)[O-])c2)c1 +O=C1CCc2ccc(OCCCCN3CCC(O)(c4ccc(Cl)cc4)CC3)cc2N1 +COc1ccc(CC2CCCC2)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)Nc2cnn(C)c2)cn1 +C=CCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)c2cc1OC +O=C(N(CCN1CCN(c2ccccc2O)CC1)c1ccccn1)C12CCC(CF)(CC1)C2 +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCNCC2CC2)CC1 +CCCCCCc1c(-c2ccccc2)nc2ccccc2c1C(=O)NC(CC)c1ccccc1 +COCc1c(-c2cc3cccc(OC)c3s2)c2c(N)ncnn2c1CN1CCNC(=O)C1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CC(CO)C2)c(-c2cccnc2)c1 +CC(C)(CCN)CN(CC1Cc2ccccc2CN1)C1CCCc2cccnc21 +O=c1cc(OCc2ccccc2Cl)ccn1-c1ccc(OCCN2CCCC2)cc1 +O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccncc3)cc(-c3ccc4c(c3)OCO4)c2)c1CCC(=O)O +COc1ccccc1N1CCN(CCC(O)c2ccc([N+](=O)[O-])cc2)CC1 +CCCC(=O)Oc1ccc2nc(S(N)(=O)=O)sc2c1 +O=[N+]([O-])c1c(Br)c(Cl)cc2nc(O)c(O)nc12 +COCCCN1CC(C)N(C(=O)N2Cc3c(NC(=O)c4ocnc4C)n[nH]c3C2(C)C)CC1C +CN1CCN(c2cc(-c3ccc(I)cc3)nc(N)n2)CC1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(N4CCN5CCCC5C4=O)cn3)nc2n1C1CCCCC1 +COc1cccc(C)c1Oc1ccc(S(=O)(=O)Nc2ccc(F)cn2)cc1C#N +O=C(CN1CCN(c2cccc3c2cnn3-c2ccccc2F)C1=O)N1CCCC1 +Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc2nc(N3CCNCC3)cnc2c1 +CCCCCCCCCCCC(=O)NC(CCC(=O)NC1CCCCNC1=O)C(=O)O +Cc1ccc(F)cc1C(=O)Nc1ccc(N2CCC(N3CCCC3C)C2)cc1C(F)(F)F +Cc1cccc(CC(NC(=O)C(c2ccccc2)c2ccccc2)C(=O)NC(C#N)COCc2ccc(C(=O)O)cc2)c1 +CC(c1ccccc1)N(C)C(=O)Nc1nc(-c2ccncc2)cs1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCN(c2ccccc2Cl)CC1 +CC(=O)NCCCNC(=O)C12CC1C(n1cnc3c(NC(C4CC4)C4CC4)nc(Cl)nc31)C(O)C2O +O=c1nc(Nc2ccc(OC3CCCC3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c(=O)n1CCO +CNCc1cc(-c2ccc3c(C(=O)NCCN(C)C)cc4n[nH]c(=O)n4c3c2)cs1 +O=C1C2=C(C3=NCCc4c(Br)[nH]c1c43)C1(C=C(Br)C(O)C(Br)=C1)CCN2 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(OC2CCOCC2)c(-c2cncnc2)c1 +O=C1Nc2ccc(S(=O)(=O)N3CCCC3COCCF)cc2C1=O +CC(C)(C)c1ccc(C(=O)Nc2ccccc2S(N)(=O)=O)cc1 +CC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)cc3)c2)c2cncnc21 +CN(Cc1nc2ccccc2n1C)C(=O)c1ccc2c(c1)CN(C)C(=O)C(CC(=O)O)N2 +CCOc1ccccc1CC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3OCC)s2)s1 +CNC(=O)c1c(C(N)=O)nn2c1C(C)COc1ccc(C#CC(C)(O)c3cc(C)on3)cc1-2 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCCN +CN1CC2(C(=O)NC(=O)NC2=O)N(c2ccc(Oc3ccc(F)cc3)nc2)C1=O +Cc1ccn2c(C(=O)Nc3cc(-c4noc(C5CC(F)C5)n4)ccc3C)cnc2c1 +COc1cc(OC)cc(C(=O)N(CCCc2ccccc2)Cc2ccc(Oc3cccc(C(=O)O)c3)cc2)c1 +O=C(O)COC(CCCCNS(=O)(=O)c1ccc(Cl)cc1)CCCc1cccnc1 +Cn1cc(C(=O)c2ccn3c2CSC3c2cccnc2)c2ccc(-c3ccc(F)cc3)cc21 +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(N3CCOCC3)nc12 +CCc1ccc2c(-c3ccc(S(C)(=O)=O)cc3)c(-c3ccc(F)cc3)nn2n1 +O=C(Cc1ccc(CCCCc2ccc3[nH]ccc3c2)cc1)NO +COc1ncc(-c2cc(F)cc(-n3nnc(-c4ccccn4)n3)c2)cn1 +COc1ccc(C(F)(F)F)cc1NC(=O)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1 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+COCCN(CCOC)c1nc(C)nc2c1nnn2-c1c(C)cc(C)cc1C +Cc1cccc2nc(-c3cccnc3N3CCN(C4CCN(C)CC4)CC3)oc(=O)c12 +COC(=O)c1ccc2c(c1O)C(=O)c1ccccc1C2=O +CC(=O)Nn1c(Cc2csc(NCCC(=O)O)n2)nnc1SCC(=O)NN +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccnc(Cl)c4c3)CC1)C2 +Nc1ccc(-n2nc3c(=O)[nH]c4ccccc4n3c2=O)cc1 +C#Cc1cccc(N2C(=O)c3ccccc3C2(O)c2ccc3[nH]c(NC(=O)OC)nc3c2)c1 +O=C(NNc1cccc2nc(Cl)ccc12)C12CC3CC(CC(C3)C1)C2 +Cc1c(OCC2CN(C)c3ccccc3O2)ccc(C(=O)Nc2cc(CC(=O)O)ccc2Cl)c1C +Fc1ccc(-c2nc(-c3ccccn3)c(C3CCN(CCc4ccccc4)CC3)s2)cc1 +COc1ccccc1-c1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)C(=O)O)cc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NN)cc3)[nH]c2n(CCC)c1=O +CCC=CCC=CCC1(O)C=C(Cl)C(=O)C1=CC(OC(C)=O)C(CCCC(=O)OC)OC(C)=O +CCN1CCC(c2ccccc2)=C(C(=O)OCCc2ccc(OC)cc2)C1 +CN1CC(NC(=O)c2ccc3cc(Oc4ccc(C(F)F)cn4)ccc3n2)CC1=O +NC(=O)C(=O)NNC(=O)Nc1cccc2c1C(=O)c1c-2n[nH]c1-c1ccc(O)cc1 +c1ccc(-c2nn(-c3ccccc3)[n+](-c3cccc4ccccc34)n2)cc1 +COc1ccc(N2CC=C(c3ccc(OC)c(OCCN4CCCCC4)c3)C2=O)cc1Cl +O=C(Nc1ccc(-c2ccccc2)cn1)c1cccc(Cl)c1 +CC(O)CNC(=O)C(Cc1ccccc1)N(C)C(=O)C(Cc1ccc2ccccc2c1)N(C)C(=O)C=CCC(C)(C)N +CN(Cc1ccccc1)Cc1nnnn1C1CCN(Cc2ccc(-n3ccnc3)cc2)CC1 +COc1ccc2c(c1F)C(=O)N(CC1(C#Cc3cccnc3)NC(=O)NC1=O)C2 +COc1cc2[nH]c(C)c(-c3ccc(O)cc3)c(=O)c2cc1Cl +CCOC(=O)N=C(N)Nc1ccc(-c2ccc(-c3ccc(NC(N)=NC(=O)OCC)cc3)cc2)cc1 +COCC1CN(C(=O)c2c(Oc3c(C)cccc3C)n(C3CCCCC3)c3cccnc23)CCN1 +Cc1ccc(C(=O)N(N=C2C(Cl)=C(Cl)C(Cl)=C2Cl)C(=O)c2ccc(C)cc2)cc1 +CN(CCCCNc1c2c(nc3ccccc13)CCCC2)CCCNc1c2c(nc3ccccc13)CCCC2 +c1cc(Nc2[nH]nc3ccnc(OC4CCOCC4)c23)ccn1 +O=[N+]([O-])c1c2c(cc3nc(O)c(O)nc13)CCC2 +CC(C)(C)Oc1ccc(CC2C(=O)Nc3ccccc3N2Cc2ccc(C(=O)NO)cc2)cc1 +Cc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2F)c1 +CC(C)C1CN(CCN2CCN(C)CC2)C(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1 +CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(-c4cccc(OC)n4)cc32)c1C +Cc1ccc(Nc2nc(NN=Cc3ccc4c(c3)OCO4)nc(N3CCOCC3)n2)cc1 +CC(C)(O)c1nc(-c2cccc(CNC(=O)c3cnc(-c4ccccn4)nc3)c2)no1 +CC1=C(CCCCCC(=O)O)C(=O)c2ccccc2C1=O +COC(=O)c1c(NC(=O)CSc2ccc([N+](=O)[O-])cc2)cnn1CCc1ccccc1 +COc1cc(CNCCN2CCC(Cc3ccccc3)CC2)ccc1O +COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+](=O)[O-] +Nc1ncnc2c1c(-c1ccc3nc(Cc4ccccc4Cl)[nH]c3c1)nn2C1CCC(N2CCOCC2)CC1 +O=C(NCc1ccccc1O)c1cc(C(=O)c2ccccc2F)c[nH]1 +COC(=O)C1C(c2ccc3ccccc3c2)CC2C(O)CC1N2C +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)c(C(C)=O)cc21 +CCCCc1nc(C)n(Cc2occc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Cn1ncnc1COc1nn2c(-c3cc(CO)on3)nncc2c1C(C)(C)C +Nc1ncn(CC(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)n1 +CC1CN(C(=O)c2ccc(N(C)C)cc2)CCN1c1nc(-c2ccncn2)cc(=O)n1C +COc1cccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOCC4)N3)n2)n1 +CC(NC(=O)c1cc(Cl)cnc1Oc1ccc(F)cc1)c1ccc(C(=O)O)cc1 +CCOC(=O)C1(Cc2ccc(OCc3cc(CC(C)C)nc4ccccc34)cc2)CC1C(=O)NO +CNc1ccc(C#CCC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N(C)C2CCCC2)cc1 +Nc1nc2c(s1)Cc1cccc(OP(=O)(O)O)c1-2 +O=C(Nc1cccc(CN2CCOCC2)n1)Nc1cccc2c1C1CCCCN1C2=O +Cc1ccc(N(C(=O)N(C)CCCN2CCC3(CCc4ccccc43)CC2)c2ccc(F)c(F)c2)cc1 +Cc1cc(C)c(NC(=O)C(C)(C)CCCCCCc2ccccc2)c2c1CC(C)(C)O2 +CCCn1nc(C(C)(C)C)c(C(=O)OC)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(N(C)c2nc(SC)nc3ccccc23)cc1 +Cc1cccc2c1N(C(=O)CSc1ncc(C(F)(F)F)cc1Cl)CCC2 +CC(C)(C)CCN1C(=O)C(NC(=O)Nc2ccccc2)C(=O)N(c2ccccc2)c2ccccc21 +COc1ccc(-c2nc(-c3ccc(C(F)(F)F)cc3)oc2Sc2nc3ccccc3s2)c(OC)c1OC +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(-c4csc(C)n4)s3)CC2)nc1 +Cc1ccc(-c2cnc(C3CC3)o2)cc1S(=O)(=O)NC1CCC(O)CC1 +O=C1C(=O)N(Cc2cn(CCF)nn2)c2ccc(S(=O)(=O)N3CCC3COc3cccnc3)cc21 +COc1cccc(CN2CCCC(CNC(=O)c3ccc(F)cc3)C2)c1OC +Cc1nc(C#Cc2ccc(-c3cc(F)cc(C#N)c3)nc2)cs1 +CC(C)CN1CCCC1c1ccc(NC(=O)Nc2ccccc2N2CC(C)(C)c3c(-c4ccc(F)cc4)ccc(O)c32)cc1 +CS(=O)(=O)c1ccc(COc2ccccc2CNCC(O)c2cc(Br)cs2)cc1 +Cc1ccc2c(Nc3ccc(Cl)cc3)nccc2c1Nc1ncccc1-c1ccncn1 +Cc1cc(N2CCOCC2)nc(N(CCCNc2ccnc3cc(Cl)ccc23)Cc2ccc3c(c2)OCO3)n1 +N=C(c1ccc(C(=O)N2CCN(S(=O)(=O)c3cc4cc(Cl)ccc4[nH]3)CC2)cc1)N1CCCCC1 +CC(C)(C)C(NC(=O)C(Cc1ccc2ccccc2c1)C(O)C(=O)NO)C(N)=O +Cn1c2c(c3cc(S(=O)(=O)n4ccc5ncccc54)ccc31)C1CCC(C2)N1 +NC(=O)C1CC=C(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +Cc1cc(Cc2nc3n(n2)Cc2c(C)ncn2-c2ccc(Cl)cc2-3)on1 +CC1CN(c2cncnc2)Cc2cc(NC(=O)c3cc(CN4CCN(C)CC4)cc(C(F)(F)F)c3)ccc21 +Cc1nn2c3c(cnc2c1S(=O)(=O)c1ccccc1)CNCC3 +CCNC(=O)C1OC(n2cnc3c(NC4CC5CC4C4OC54)[n+]([O-])cnc32)C(O)C1O +O=C1N(Cc2ccc(O)cc2)C(Cc2ccccc2)C(O)CN(S(=O)(=O)c2cccc(Br)c2)N1Cc1ccc(O)cc1 +CCOC(=O)C=C1CC2(CCCC2)CC(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCCN(c2nsc3ccccc23)CC1 +CCN1CCN(c2ccc(Nc3cc(N(C)C(=O)Nc4c(Cl)c(OC)cc(OC)c4Cl)ncn3)cc2)CC1 +Cc1oc(C2CCC(C)N(C(=O)c3ccccc3-n3ncnn3)C2)nc1C(C)(C)O +Cc1cc(C)c(=O)n(C(C(=O)NS(=O)(=O)c2ccc(C(C)C)cc2)c2ccc3c(c2)OCO3)n1 +CCOC(=O)c1cc(Cc2cccc(Br)c2)c(=O)n2c1CCC2 +CC1C(c2cccc(C(F)(F)F)c2)OC(=O)N1C(=O)NCc1cncc2cccnc12 +CC(N)c1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 +CC1=C(N2CC2)C(=O)c2nc3n(c2C1=O)CCC3 +CCC(NC(=O)c1c([S+](C)[O-])c(-c2cccc(F)c2)nc2ccccc12)c1ccccc1 +CNS(=O)(=O)c1ccc(OC)c(Nc2cc(Nc3ccc(Cl)cn3)ncn2)c1 +O=C(O)CN1C(=O)C(=O)N(Cc2ccc(Cl)c([N+](=O)[O-])c2)C1=O +O=C(Nc1ccc(OCCN2CCCC2)cc1)Nc1ccc(-c2nc(N3C4CCC3COC4)nc(N3C4CCC3COC4)n2)cc1 +COc1cc2c(cc1OC)-c1n[nH]c(Nc3cc(Cl)cc(Cl)c3)c1C2 +CC(C)(CC(=O)N1CCCC1)NCC(=O)N1CC(F)CC1C#N +Cc1nc(NC(C)c2cccc(-c3ccc(N4CCNCC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +COC1CC(C(=O)N2CCc3nc(C#Cc4ccccc4)sc3C2)C1 +CN(C)c1ccc(-c2cn3c(=O)c4ncn(C5CC(N=[N+]=[N-])C(CO)O5)c4nc3[nH]2)cc1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccccc4)cc3)c(Cl)c2n(CCC)c1=O +COc1cc(OCc2csc(N3CCCC3C)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +CN(C)Cc1ccc(-c2cc(C#N)c(NCc3cnco3)n3cnnc23)cc1 +O=C(CCCCCCn1cc(-c2cccnc2)nn1)Nc1ccccc1Oc1ccccc1 +Nc1nc(N)c2nc(COc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)cnc2n1 +N=C(Nc1ccc2c(c1)N(C1CCNCC1)CC2)c1cccs1 +O=C(Nc1ccc(Cl)c(CN2CCC(C(=O)NC3CCCC3)CC2)c1)c1ccc2ncccc2c1 +CC1CCN(C(=O)C(C)(C)C#N)CC1N(C)c1ncnc2[nH]ccc12 +Cc1ccc(CNCCN2CCCCC2)cc1NC(=O)c1ccc(Nc2ncc(C)c(-c3ccc(OC(F)(F)F)cc3)n2)cc1 +CCCc1nc2c(n1Cc1ccc(-c3ccccc3S(=O)(=O)Nc3onc(C)c3C)c(C)c1)C(=O)CCCC2 +C=Cc1cc(S(C)(=O)=O)cc2c3c(n(Cc4ccc(Cl)cc4)c12)C(CC(=O)O)CC3 +Cc1nn(Cc2ccccc2N(C)C)c(C)c1CC(=O)NCc1ccc(F)cc1Cl +C=CC(=O)Nc1cccc(C(=O)Nc2cccc(Nc3cc(-c4c(-c5ccc(F)cc5)nc(SC)n4C)ccn3)c2)c1C +CN(C)CCOc1ccc(C(=C(CCC(F)F)c2ccccc2)c2ccc(O)cc2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NCC3CCC3)c2cn1)c1ccccc1 +CCOCCC1(Oc2ccc(Oc3ccccc3F)cc2)C(=O)NC(=O)C(N)C1=O +Cc1cnc2[nH]cc(Cc3cnc(NCc4cccc(N5CCOCC5)n4)nc3)c2c1 +CN1CCN(CCCC#Cc2cnn3c(-c4cccc(NC(=O)c5cccc(C(F)(F)F)c5)c4)ccnc23)CC1 +COc1ccc(-c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)nc1 +COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(C2CCC(C(=O)O)CC2)C3=O)c(OC)n1 +Cc1cc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)ccc1C1(O)CCC1 +COc1cc2ccccc2cc1C=NNc1ccnc2cc(Cl)ccc12 +OCC1(NCc2nc(-c3ccc(C(F)(F)F)cc3)ccc2F)CCCCC1 +CCOC(=O)C1=C(CN2CCOCC2)NC(c2nccn2C)=NC1c1ccc(F)cc1Br +Oc1ccc2c(c1)CCC1C2CCC2(O)C(O)CCC12 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(S(=O)(=O)c2ccc(-c3ccccc3)cc2)CC1 +O=C(C=Cc1c(C(=O)O)[nH]c2c1CCCC2)Nc1ccccc1 +Cc1nc2cc(C=CC(=O)NO)ccn2c1CN(C)CC(C)(C)C +CC1CN(C(=O)OC2(C3COCC(CC4CC4)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)CC(C)N1CCO +Nc1nc(NCCNc2ncc(N3CCNCC3=O)c(-c3ccc(Cl)cc3Cl)n2)ccc1[N+](=O)[O-] +CN1CC(C(=O)Nc2nccs2)CC2c3cc(C(C)(C)C)cc4[nH]cc(c34)CC21 +COC1CC(=O)C2(C)C1C(OC(C)=O)CC1C3(C)CCC(O)C(C)(C)C3CCC12C +NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCCc4ccccc4)nc32)CC1 +Cc1cnc(Nc2ccc(C3CCN(C)CC3)nc2)nc1CCc1ccccc1C1(C(N)=O)CC1 +NCCCCCN1Cc2[nH]c3ccccc3c2CC(NC(=O)CC(c2ccccc2)c2ccccc2)C1=O +O=C(O)C1CC1c1ccc(-c2c(C3CC(c4ccc5ccccc5n4)C3)nc3c(N4CCOCC4)ccnn23)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccccc2)CC1 +Cn1c(=O)n(CC2CC2)c(=O)c2[nH]c(-c3cnn(Cc4ccccc4)c3)nc21 +CC(=O)Nc1cccc(-c2ccc(C(=O)N3CCc4c([nH]c5ccccc45)C3c3ccc4c(c3)OCO4)o2)c1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C)c1ccccc1C(=O)N2C +CC=CC=CC=CC[N+](C)(CCCCCCCCCCCCCC)Cc1ccccc1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)O +Cn1c(=O)c2c(nc3n2CCCN3Cc2ccc(Cl)c(Cl)c2)n(C)c1=O +O=C(O)C1CCCCC1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1ccc(N2CCC(F)(F)C2)cc1F +Fc1ccc2[nH]cc(C3=CCN(CCc4coc5ccccc45)CC3)c2c1 +O=S(=O)(c1ccc(-c2cnc(C3CC3)o2)cc1)N1CCOc2ccccc21 +O=C(NC1(CO)CC1)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CC(C)(NS(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1)C(F)(F)F +O=C(O)C=Cc1ccc(C(=C(c2ccccc2Cl)C2CCC2)c2ccc3[nH]nc(F)c3c2)cc1 +N#Cc1cnc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)nc1OC1CCOC1 +CCc1cc2c(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3F)ccnc2cc1OC +NCCNC(=O)c1cncc(-c2cnc(Nc3cc(N4CCOCC4)ccn3)s2)c1 +CCC(C)Sc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br +O=C(O)Cn1c2c(c3c(F)cc(F)cc31)CCN(Cc1ccccc1)C2=S +CCCCOc1ccc(S(=O)(=O)N(CCc2cccs2)Cc2c[nH]cn2)cc1 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(Br)cc2)nc1 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CC6CCC(C5)N6C)ccn34)c12 +ON=Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5c(c4)OCCO5)CC3)c2c1 +Cc1ccc(-c2ncn3c2C(C)(C)N(C(=O)N(C)C)c2ccccc2-3)cc1 +O=C(Cn1cc(-c2cccnc2)nn1)Nc1ccc(-c2ccccc2)cn1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)CN)c12 +Cc1n[nH]c2c1C(c1ccccc1I)C(C#N)=C(N)O2 +N=C(N)c1cccc(N2CC(COCc3ccccc3)CN(CC3CCN(Cc4ccccc4)CC3)C2=O)c1 +COc1cc(-c2cn[nH]c2)ccc1C(=O)NC(C)c1ccc(F)cc1 +CNC(=O)Cn1cnc2ccc(-c3cccc(OCC(O)CN4CCc5ccccc5C4)c3)cc21 +Cc1cc(-c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)ccn1 +CC(C)(O)CNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CC(C)(C)NCc1cc(Nc2ccnc3cc(Cl)ccc23)cc(C2CCCCC2)c1O +COc1ccccc1Oc1ncccc1C(=O)NCC(O)CN1CCN(c2ccccc2OC)CC1 +CCOC(=O)c1ncn2c1CN(C(C)=O)c1ccccc1-2 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cc(NS(C)(=O)=O)cc(C(C)(C)C)c2)CCCCC1 +O=C(COc1ccc(Cl)cc1)NNC(=S)NCc1ccccc1-c1ccccc1 +COc1c(-c2nc3ccccc3[nH]2)c(O)cc2oc(C)cc(=O)c12 +Cc1cc(C(=O)NCC2C(C(=O)Nc3ccc(Br)cc3)C3C=CC2C32CC2)nn1C +CS(=O)(=O)N(Cc1ccncc1)c1ccc(Nc2ncc3cnn(C4CCCCCC4)c3n2)cn1 +Cc1nc(NC(C)c2cccc(-c3cnc(N4CCN(C)CC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CN(C)C(=O)Oc1ccc(CC(Nc2nc(N(C)C3CCCCC3)nc3ccccc23)C(=O)O)cc1 +O=C1N(c2ccccc2)C(CCc2ccccc2)C(O)C(Cc2ccccc2)N1c1ccccc1 +CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1c(F)cc(F)c(F)c1F +CC(O)c1cc(C(=O)NC(C)c2ccccc2F)ccc1-c1cn[nH]c1 +OC(c1ccc(Cl)cc1)(c1ccc(C(F)(F)F)cc1)c1cccnc1 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3ccc(N)c(Br)c3)C2O)c1 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+O=C(Nc1ccc2[nH]cc(C3CCN(Cc4ccccc4)CC3)c2c1)c1ccc(F)cc1 +COc1ccc(C(Cc2ccncc2)c2cccc(OCc3ccccc3)c2)cc1OC1CCCC1 +CCNC(=O)OCc1c(COC(=O)NCC)c2sc3ccccc3n2c1-c1cc(OC)c(OC)c(OC)c1 +CN1CCN(c2cc(Nc3cc(C4CC4)n[nH]3)nc(NCc3cc(-c4ccc(F)cc4)no3)n2)CC1 +COc1cccc(NC(=O)c2ccc(N3CCCCC3)c([N+](=O)[O-])c2)c1 +Cc1ccc(C(=O)N2c3ccccc3C(Nc3ccccc3)CC2C)cc1 +Cc1cccc(CN2CCN(c3ccccc3OC(C)C)CC2)c1 +Cn1cc(N(Cc2ccccc2)c2ccc(C#N)cc2)cc1C(=O)N1CCCC1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc4nnnn4n3)c2)c2cncnc21 +O=C(c1nc2sc3c(n2c1Cl)CCCCC3)N1CCN(C2CCCC2)C(=O)C1 +CCc1ncnc(NC(C)c2ccc(OC(=O)NCCCOCCCNC(C)=O)cc2)c1Cl +c1ccc2[nH]c(-c3ccc(OCCCOc4ccc(-c5nc6ccccc6[nH]5)cc4)cc3)nc2c1 +COc1ccc(N2CCN(C(=O)c3cc4c(s3)-c3ccccc3S(=O)(=O)C4)CC2)cc1 +COc1cccc(-c2ccc3c(c2)C2(COC(N)=N2)C2(COC2)C2(CCC2)O3)c1F +COc1ccc(Nc2nc(N3CCCC(C(=O)Nc4ccc(C(=O)O)cc4)C3)nc3scnc23)cc1OC +CCC1CCNc2cc3c(cc21)c(C(F)(F)F)cc(=O)n3C +COc1ccc2ccc3c(c2c1)CC(N)C(c1ccccc1F)O3 +CC(=O)NN=CC(C)(C)C1CCC2(C)C(CCC3C4C5OCC4(CCC5(C)C)CCC32C)C1(C)CC#N 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+CCCCCCn1c(=O)c(C(=O)Nc2ccc(C(=O)O)cc2)c(O)c2ccccc21 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccc(F)cc4C)no3)ccc21 +CN(C)CCNc1ccc2nc3c4c(nccc4c2c1)-c1ncccc1C3=O +Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1CC1CCCCC1 +O=C(O)c1ccc(CCC2C(=O)CCC2C=CC(O)Cc2ccc(F)cc2)cc1 +CC(Cc1c[nH]c2ccccc12)NCC(O)c1cccc(NS(=O)(=O)c2cccs2)c1 +O=C(NN1CC=C(c2ccc3[nH]cc(CCN4CCCC4)c3c2)CC1)C1CCCCC1 +CC12CCCC(C=CC(=O)NS(=O)(=O)c3cc(F)cc(F)c3)=C1N(Cc1ccc(F)c(F)c1)C(=O)C2 +Cc1nc(-c2cccc(C(=N)N)c2)c(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)s1 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C)nc2C(O)C(C)C)n1 +Fc1cc(F)cc(Nc2nccc(-c3c(-c4ccccc4)nn4ncccc34)n2)c1 +NCC1CN(c2ncnc3[nH]c4cnccc4c23)CCO1 +O=C1N(Cc2ccccn2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +Cc1ccc(C(=O)c2sc3[nH]c(=O)c(C(=O)O)cc3c2N)cc1 +Fc1ccc(-c2nn3ncccc3c2-c2ccnc(Nc3ccc4c(c3)OCCO4)n2)cc1 +COc1cc2nc(N3CCN(C(=O)C=CC(=O)c4ccccc4)CC3)nc(N)c2cc1OC +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)O +COc1nc(N2CCOCC2C)c2ccc(-c3ccc(OC)c(CO)c3)nc2n1 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+CC(=O)Nc1ccc(Sc2nc(Nc3cc(C)[nH]n3)cc(C)c2C#N)cc1 +O=C(O)c1[nH]c2ccc(Br)cc2c1CCN1C(=O)c2cccc([N+](=O)[O-])c2C1=O +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2cc(N3CCCCC3)ccc2o1 +CCCCNc1ccc(-c2c(N)nc(N)nc2CC)cc1[N+](=O)[O-] +N#Cc1ccc2oc(NC(CC3CCCCC3)c3ccccc3)nc2c1 +Cc1cc(C(=O)Nc2cc(C(=O)c3ccc4c(C=Cc5ccccn5)n[nH]c4c3)ccc2C)n(C)n1 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1N(C)C +CC1CC(=O)C(O)C2(O1)OC1CC(=O)OC1C1=C2C(=O)c2c(O)cccc2C1=O +O=C1NCCCCC1N(CCCCc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OCC[N+](C)(C)C)cc2)C1O +CNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(F)cc4)ccc3C)CC2)ncn1 +CCCn1c2ccc(NC(=O)Nc3ccc(SC)cc3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +Nc1ccc(-c2ccccc2)cc1NC(=O)c1ccc(CNC(=O)C2CC2)cc1 +Cn1ccc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cccc(F)c2)C(N2CCC2)CC3)c1 +N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)NCc3ccccc3C(=O)O)c(Cl)c2)cc1 +O=C1OCCc2cc(C3CN4CCN(C(=O)Cc5cnc(-n6cnnn6)cn5)CC4CO3)ccc21 +COc1cc(F)ccc1N1CCN(CCC(=O)c2cc(C)sc2C)CC1 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+COc1ccc(S(=O)(=O)N2CC(C(=O)N3CC(CN)C3)c3ccccc32)c2ccccc12 +CC(=O)N1CCC(OC(N)=O)(c2ccc(CN3C(C)CCC(c4ccccc4)S3(=O)=O)c(F)c2)CC1 +C=C(C)N1Cc2cccc3[nH]c(=S)n(c23)CC1C +COc1nc2cccc(C(=O)O)c2n1Cc1ccc(-c2ccccc2-c2nsc(O)n2)cc1 +CNc1ccc(C=Cc2ccc(-c3nc4ccc(OCCCF)cc4o3)cc2)cc1 +CN1CCCC1Cn1nc(CC2CCCCC2)c2ccccc2c1=O +Cc1cccnc1CN1CCC(Oc2ncnc3c2ccn3Cc2ccccc2)CC1 +CC1(C)CN=C2C(=O)C(O)=C2N(CCP(=O)(O)O)C1 +O=C(Nc1cccc(Cl)c1N1CCN(Cc2ccco2)CC1)c1ccc(Br)o1 +CC(Oc1nc2c(c(Nc3ccc(S(=O)(=O)N4CCCC4)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2)C1CC1 +C#Cc1ccc2c(c1)C(=O)N1CCC1c1c(-c3nc(CC)no3)ncn1-2 +CCOC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1-c1ccc(C)s1 +Cc1ccc(C(=O)NC2CCN(C3CCC(N(C)C(C)C)CC3CS(C)(=O)=O)C2=O)cc1C(F)(F)F +CN1Cc2cccc(Oc3nc(Nc4ccc(OC5CCOCC5)cc4)ncc3C(F)(F)F)c2C1=O +CC1OC(=O)N2CC(c3nc(-c4ccc(C(=O)Nc5cc(C6CC6)ccn5)cc4)c4c(N)nccn34)CCC12 +FC(F)(F)c1cccc(C(F)(F)F)c1-c1ccc2[nH]c(C=CC3CCCCC3)nc2c1 +CC(C)NC(=O)OCC1OC(n2cnc3c(NC4CCOC4)ncnc32)C(O)C1O +NC(=O)Cc1ccccc1-c1ccc(COC2CCC(N3CCCCCC3)C2OCC=CCCC(=O)O)cc1 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+O=[N+]([O-])c1ccc(C[n+]2ccc(-c3cc4cc(Br)ccc4o3)cc2)cc1 +O=C(CCCCOc1ccc(-c2cc(=S)ss2)cc1)NO +CC1CCC2C(CN=[N+]=[N-])=C(C(F)(F)F)OC3OC4(C)CCC1C32OO4 +CC(C)C(NC(=O)C(CC(=O)O)NC(=O)CNC(=O)COc1ccc(C(=N)N)cc1)C(=O)O +CN(CC1=Nc2c(N)nc(N)nc2NC1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +O=C1C2Cc3ccccc3CN2C(=O)N1CCCN1CCCCC1 +Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)NCCNc1c3c(nc4ccccc14)CCCC3)O2 +COc1ccc2c(c1F)C(=O)N(CC1(C#Cc3ccc(C4(O)CCNCC4)cc3)NC(=O)NC1=O)C2 +COc1ccc(CNc2nc(N3CCC4(CC4)C3)ncc2C(=O)NCCN2CCOCC2)cc1Cl +COc1c(C(C)Nc2ncnc(N)c2C#N)cc(Cl)c(F)c1-c1cncc(C#N)c1 +COc1cc(C2C(C#N)=C(N)Oc3c2ccc2c3CCCC2)cc(Br)c1OC +CC(C)CC(NC(=O)C(N)Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)NO +Fc1ccc2[nH]c3c(c2c1)CN(CCCCc1ccncc1)CC3 +O=C(c1nn(Cc2cc(Cl)cs2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CC(=O)N1CCC(C(=O)N(CCCN2CCC(CNC(=O)c3ccsc3)CC2)c2ccc(C)c(Cl)c2)CC1 +O=C(c1ccc(F)cc1)C1CCN(C2CCCCC2O)CC1 +CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(OCCN(C)C)nc3)c2n1 +OC1(c2ccccc2)CCN(C(c2ccccc2)c2ccccc2Br)CC1 +CC1NC(C(=O)N2CCCC2C#N)CC1C(=O)N1CCOCC1 +CCOC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1ccco1 +COc1ccc(SCc2cnc(SCc3c(F)cc(C(=O)NCCS(=O)(=O)O)cc3F)n2-c2ccc(F)cc2)cc1OC +COc1cc(OC)cc(N(CCCN)c2ccc3ncc(-c4cnn(C(C)C)c4)nc3c2)c1 +CNCC(C)c1ccc(-c2c(O)cc(C)c3[nH]c(=O)c4sccc4c23)cc1F +COc1cccc(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)c1N +Cc1ccc(-c2nc3c(Cl)cc(Cl)cc3c(=O)n2O)cc1 +Cn1ncc(NC(=O)c2ccc(F)c(-c3cccc(F)c3Cl)n2)c1C1CCC(N)C(F)CO1 +O=C(O)Cc1sc(-c2ccccc2)nc1-c1ccc(Cl)cc1 +CC12CCN(C(=O)C3C4CC5CC(C4)CC3C5)C(Cc3c(O)cccc31)C2(C)C +COc1cccc(N(C)C(=O)c2ccc(-c3ccccc3)s2)c1 +CCc1cc(=O)oc2nc(OCc3ccccc3)[nH]c(=O)c12 +Nc1ccc(-c2cnc(NC(=O)CN(Cc3ccccc3)C(=O)c3ccncc3)s2)cc1 +O=C(Nc1ccc(S(=O)(=O)C2CCCCC2)cc1)c1ccc([N+](=O)[O-])o1 +[C-]#[N+]c1ccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 +CC(=O)c1ccc(Cl)cc1OCC1CN(Cc2ccc(Cl)cc2)CCCO1 +CCCCC1=NCC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +NC(CC(=O)N1CCCC1CNc1ncccn1)Cc1cc(F)c(F)cc1F +COc1cccc2sc(C3(NC(=O)CC(N)Cc4ccccc4F)CCS(=O)(=O)CC3)nc12 +O=C(CNCc1ccc(Oc2ccccc2)cc1)Nc1ccc2ccn(CCN3CCCC3)c2c1 +Cc1cc(Oc2ccc(C(=O)NC3CN(C(=O)OC(C)(C)C)CC3C(=O)NO)cc2)c2ccccc2n1 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ncc(F)cn2)CC1c1ccc(F)cc1 +O=C(CNCCO)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 +COc1ccc(Nc2nc3c(NC4CCN(S(C)(=O)=O)CC4)cccn3n2)cc1 +O=C(O)CC1CCC(c2ccc(-c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)cc2)CC1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(-c3cc(CO)co3)c2c1=O +CCSCC1CC(O)(c2ccccc2)C(c2ccccc2)C(c2ccc(Br)cc2)O1 +COc1ccc(F)c(-c2cc(C)c(Nc3ccc(C)cc3C(=O)O)cn2)c1 +CS(=O)(=O)NC1CC2CCCCC2C1C=Cc1ccc(-c2cccc(F)c2)cn1 +CCN1CCN(CC)CC(NC(=O)c2cc(Cl)c(NC)nc2OC)C1 +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(NC(=O)Nc3ccccc3F)CCc3ccccc32)c1 +CCOC(=O)c1[nH]cc2nc3ccc(OC)cc3c-2c1COC +[H]C(O)C1NC(c2c[nH]c3c(=O)[nH]cnc23)C(O)C1O +Cc1c(N(Cc2ccc(-c3ccccc3)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(OCC(F)(F)F)c1 +Cc1cccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(CCO)c5)cnc(N)c34)cc2F)c1 +O=Cc1c(O)ccc2cc(-c3ccc(C(=O)O)cc3)ccc12 +COc1cc(-c2ccc(Cl)c(F)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(O)CN1CCN(c2ccc(Nc3ncc4ccc(-c5ccccc5N(C)S(C)(=O)=O)n4n3)cc2F)CC1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CCNCc1ccccc1 +N#Cc1cccc(-c2ccc3c(c2)C2(CCCCC2)C(=S)N3)c1 +CCN(CCCCCSc1nc(-c2ccc(SC)cc2)c(-c2ccccc2)[nH]1)c1nc2ccccc2o1 +CCC(=O)Nc1cccc(Nc2cc(Nc3cccc(Br)c3)ncn2)c1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCN(C)CC3)cc2c1=O +FC(F)(F)Cc1nnc2c(Cl)c(N3CCC(c4ccccc4)CC3)ccn12 +NS(=O)(=O)Oc1ccc(NC(=O)Nc2ccc(Cc3ccccc3)cc2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1C1CCC(C)(C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCS(=O)(=O)CCC1OCCC2(S(=O)(=O)c3ccc(Cl)cc3)c3c(F)ccc(F)c3OCC12 +COc1ccc2c(c1)CCN1C(=O)C3CCCC(C21)N3S(=O)(=O)Nc1ccc(N2CCOCC2)nc1 +COCCN1CC(C)(C)Oc2nc(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)Nc4ccon4)cc3)c2C1=O +CCN(Cc1ccccc1)C(=O)C1(c2ccccc2)CC1CN +CCCSc1nc(NC2CC2c2ccc(F)c(F)c2)c2nnn(C3C=CC(O)C3O)c2n1 +CCCc1ccc(-c2ccc(N(CC3(N)CCCC3)C(=O)C3CC3c3cccc(F)n3)cc2)cc1 +O=C1C=C(c2cccc([N+](=O)[O-])c2)c2ccccc2C1=O +CC1C(=O)N(CCOCc2ccccc2)CCCN1C(=O)CC(N)Cc1cc(F)c(F)cc1F +COCc1cccc(NS(=O)(=O)c2ccc(C)c(N3CCNCC3)c2)c1 +Cc1ccc(-n2nccn2)c(C(=O)N2C3CCC2C(COc2ccc(C(F)(F)F)cn2)C3)n1 +CCN(CC)CCNC(=O)c1ccc(C(CC)(CC)c2ccc(C#CC(O)(CC)CC)c(C)c2)n1CC +CN(C)CCc1cccc2[nH]c(-c3nc(CCC4CCCC4)no3)cc12 +COC(C)C(=O)N1CCN(c2ccc(CN(CC(C)C)S(=O)(=O)Cc3ccccc3)cc2)CC1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1cccc(Cl)c1Cl +FC(F)(F)c1ccc(-c2ccc3ncc(-c4ccncc4)n3n2)cn1 +CCCCCN(CCCCC)C(=O)Cc1coc(-c2ccccc2)n1 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cccc(-c4ccncc4)c3)o2)c1 +Nc1ccc(-c2ccc(-c3ccccc3S(=O)(=O)NC(c3ccccc3)C(F)(F)F)cc2F)cn1 +CCC(C)C(=O)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +O=C(O)c1cn(Cc2ccc(S(=O)(=O)F)cc2)c2ccccc2c1=O +CNC(=O)c1cc2ccc(CCNC(=O)Nc3cc(C(F)(F)F)ccc3OC)cc2cn1 +CN(C)Cc1cc2c(nc1C=O)N(C(=O)Nc1ccc(C#N)cn1)CCC2 +CC(=CCc1ccccc1)CCC(=O)CC1CC(O)CC(C)=CCC=CCC(CC(=O)O)=CC(=O)O1 +CC(=O)N1CCC(Oc2cncc(-c3cnc4c(c3)CCCN4C(C)=O)c2)CC1 +COc1ccc(OC)c(-c2cccc3c(N)c(C(=O)NCCC(F)(F)F)nnc23)c1 +CCOC(=O)C(C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(C)c12 +c1ccc(CCNc2nc(-n3ccnc3)nc3ccccc23)cc1 +CCCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1nc(C)c(CC)c(=O)[nH]1 +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NC1CCC(O)(c2ccnn2C)CC1 +Cc1c(N2C(=O)OCC2C(O)C(F)(F)F)ccc(C#N)c1Cl +CCc1ccc(NS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +CCNC(=O)C1OC(n2cnc3c(N)nc(NCCc4ccc(F)cc4)nc32)C(O)C1O +CC1CCC(Oc2cccc3ncccc23)CN1C(=O)c1ccccc1-n1nccn1 +Cc1ccc(N2CCN(CCNC(=O)c3ccc(F)cc3)CC2)cc1 +Cc1ccc(SCC2NC(c3c[nH]c4c(N)ncnc34)C(O)C2O)cc1 +CCc1c(C(=O)NCc2ccc(Cl)c(Cl)c2)nn(-c2ccc(Cl)cc2Cl)c1-n1cccc1 +O=C(NS(=O)(=O)C1CC1)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1 +Clc1cccc(Nc2cncc(-c3cncc(NCCCN4CCOCC4)c3)n2)c1 +Cc1ccc(NC(=O)c2ccncc2C(C)(C)C)cc1Nc1nc2ccccc2n1-c1cc(N)ncn1 +O=C(N1CCCCC1)N1CC(OC(c2ccc(Cl)c(Cl)c2)c2cccnc2Cl)C1 +CCN(CC)CC(c1c(F)cccc1F)N1CCN(C)CC1 +O=C(c1ccc(Br)cc1NS(=O)(=O)c1sc(Cl)cc1Br)N1CCCCC1 +c1cc(C2=NC3(CCCCC3)CO2)ccc1OC1CC(N2CCCCC2)C1 +COCCN(CC1CC1)c1c(OC)nn2c(-c3c(OC)cc(COC)cc3OC)csc12 +CCCOc1ccc(S(=O)(=O)N2CCN(c3ccccc3)CC2)cc1-c1nc(C(C)C)c(Br)c(=O)[nH]1 +COC(=O)C1CC(OC2CCCO2)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +CCCCCCC(C)(C)c1cc(O)c(-c2cc(C)cc(C)c2)c(O)c1 +Cc1ccc(NC(=O)c2ccc3c(c2)CCC3N2CCN(CCO)CC2)cc1Nc1nccc(-c2cccnc2)n1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCc4nocc4C3)[nH]c12 +Cc1cc(Oc2ccccc2S(=O)(=O)NC(C=O)C(=O)O)ccc1C(C)C +CCCCCOc1ccc(C(=O)NCCc2ccc(N)cc2)cc1SCCCCC +O=C(c1ccc2nc[nH]c2c1)N1CCCC2c3cccc(O)c3CCC21 +Cn1cc(-c2cnc3nnn(Cc4cc5cccnc5s4)c3n2)cn1 +CCN(C)C(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +Cc1onc(-c2ccccc2)c1COc1cc(OCc2ccccc2)ccn1 +Cn1c(OCCNc2ccccc2)nc(-c2ccncc2)cc1=O +NCCCNCCCCNCCCNC(=O)Cc1cccc2ccccc12 +COc1ccc(CC2C(O)C(O)C(Cc3ccc(OC)cc3)N(CC3CC3)C(=O)N2CC2CC2)cc1 +CNc1nc(C2CC2)c(-c2ccnc(Nc3ccc(S(N)(=O)=O)cc3)n2)s1 +CCC(C)(C)C(=O)Nc1n[nH]c2nc(N3CCCCC3)c3c(c12)CCN(Cc1ccccc1)C3 +CCc1ccc(-c2ccc3c(n2)C(=O)N(c2ccc(OCCN4CCCC4)c(OC)c2)C3)cc1 +COC(=O)c1ccc(-c2nnn3c2CN(C(=O)CC(N)Cc2cc(F)c(F)cc2F)CC3)cc1 +O=C(Cc1ccc(O)cc1)NN=C1C(=O)Nc2cccc(-c3ccc(F)cc3)c21 +Cc1c(CC(=O)O)c2cccnc2n1C(C)c1ccc(C(F)(F)F)cc1 +Cc1cccc(C(=O)NCC(c2ccc(Cl)cc2)N2CCC(F)(F)CC2)c1C +CC(C)Nc1nc(Nc2ccccc2)nc(Nc2ccc(Cl)cc2)n1 +COC12CCC3(CC1C(C)(C)O)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +O=C(O)CNC(C(=O)N1CCCC1C(=O)NCC#Cc1c[nH]cn1)C(c1ccccc1)c1ccccc1 +CC1CCCC(=NNc2nc(-c3ccc([N+](=O)[O-])cc3)cs2)C1 +CC(C)CC(NC(=O)CCCCC1CCSS1)C(=O)NC(Cc1ccc(Br)cc1)C(=O)C(=O)NCCc1ccccn1 +CS(=O)(=O)c1ccc(CNc2nccn3c(-c4ccc(O)cc4)cnc23)cc1 +CC(C=CC1=C(C)C(n2ccnc2)CCC1(C)C)=CC=CC(C)=CC(=O)O +Cc1nc2c(cnn2-c2ccccc2)c(=O)n1-c1ccc(Br)cc1 +CS(=O)(=O)NCCCCCNc1nc2c(s1)CCCc1ccc(F)cc1-2 +O=C1C=Cc2c(c(-c3ccccc3)cn2S(=O)(=O)c2ccccc2)C1=O +CCc1ccnc(C#CCN(c2cc(OC)cc(OC)c2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)n1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC1CCOCC1 +Cc1cn2cc(-n3ccccc3=O)cc(NCc3c(C)cccc3C)c2n1 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2sc(-c3ccc(C(=O)O)cc3)cc2c1 +O=c1cc(-c2ccn3c(-c4ccccc4)cnc3c2)ccn1CCCO +COc1cc(C(C)NC(C)c2cccc(Cl)c2)nn1-c1ccc(Br)cc1 +C=CCOC1(c2ccc(Br)cc2)SC=C(C)n2c1noc2=O +Cc1cc(C)c(S(=O)(=O)NC(C)CNc2cccc3c2cnn3-c2ccc(F)nc2)c(C)c1 +COCCCCn1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)c2c(F)ccnc21 +COc1ccc2[nH]nc(-c3cc(N4CCOC(C)C4)ncn3)c2c1 +Cc1nnc(SCCCCOc2c3ccoc3cc3oc(=O)ccc23)s1 +CNC(=NS(=O)(=O)c1ccc(Cl)cc1)C1=NN(c2ccc(Cl)cc2)C(c2ccccc2)C1 +COc1ccc(Br)cc1CN(c1sc2ccccc2c1Br)S(=O)(=O)c1ccccc1 +COC(=O)c1c(C)c2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n(C2CCCC2)c1=O +COc1cc2c(cc1OC)CN(C=Nc1ccc3c(c1)C(OC(C)=O)CCC3)CC2 +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCc3ccccc3)ccc21 +O=C1c2ccccc2C(=O)c2c(NCCCO)nnc(NCCCO)c21 +O=C(O)C=Cc1ccc(NC(=O)C2(NC(=O)c3ccc4c(c3)nc(-c3ccoc3)n4C3CCCCC3)CCC2)cc1 +Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)NC(C)C)cc1 +[C-]#[N+]c1ccc2c(c1)C1(N=C(C)C(N)=N1)C1(CCC(OC)C(C)C1)C2 +CC(C)c1nc(OCc2ncon2)c2cc(-c3ccc(Cl)cc3)c(-c3ccccc3Cl)nc2n1 +c1cc(-c2n[nH]c3cnc(-n4ccnc4)cc23)nc(N2CCNCC2)c1 +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3cc(-c4cccc5ccccc45)[nH]n3)CC2)C(c2ccccc2)C1 +O=C(C=Cc1ccc(O)c(O)c1)OCC(OC(=O)C=Cc1ccc(O)c(O)c1)c1nnn[nH]1 +CCOC(=O)C#Cc1c(C(=O)OCC)nnn1C1OC(CO)C2OC(C)(c3ccccc3)OC21 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCN1C(=O)CCC1=O +COC(=O)C1=C(Nc2ccc(Cl)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O +Cc1cnc2c(c1)N=C(N1CCN(C)CC1)c1ccccc1N2 +COc1cc2oc(C(=O)NCCCCCCCCCCNc3c4c(nc5ccccc35)CCCC4)cc(=O)c2cc1OC +CCN(Cc1ccccc1)C(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +O=C(O)C1CCCN(S(=O)(=O)c2ccc3cc4ccccc4cc3c2)C1 +CC12CCC3C(CC(Cc4ccccc4)C4=CC(=O)CCC43C)C1CCC2=O +Cc1cc(C(=O)O)nc(N2CC3CC(c4cccc(F)c4Cl)CC3C2)n1 +CCC(c1ccc(C(=O)O)c(Oc2cccc(Cl)c2)c1F)N1CCCC(n2cc(C)c(=O)[nH]c2=O)C1 +Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCCC1CCN(C(=O)CCN2CCCCC2)CC1 +Cc1nc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)cs1 +O=C(CCS(=O)(=O)c1ccc(Oc2ccncc2)cc1)NO +Cc1c(-c2ccc(C#N)cc2)nc(N)nc1N1CCN(C)CC1 +O=C(NCC1(C(=O)N2CCCCC2)CCCC1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CC(C)(Oc1ccccc1)C(=O)NCC(O)CN1CCc2ccccc2C1 +O=S(=O)(Nc1ccc(F)c(C#Cc2cnc3[nH]ncc3c2)c1F)c1cccc(F)c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)Cc1n[nH]c3ccccc13)CC2 +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1OP(=O)(O)O +OC1(c2ccc3c(c2)OCO3)CCC(N2CCN(Cc3cccc(F)c3)CC2)CC1 +Cc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)NCCCCCCCNc1c2c(nc3ccccc13)CCCC2 +CCC(CC)Cc1ccc(OCCN(C)C(=O)OC(C)C)cc1 +COCC(NC(=O)Nc1cc2[nH]nc(-c3ccc(C(F)(F)F)nc3)c2cn1)c1ccc(F)cc1 +CC(C)(O)c1cccc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)n1 +CCCN1CC(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2NCCN(Cc3ccccc3)C2=O)N(C(C)C)C1=O +Cc1ncc(C)n2nc(CCc3nc(N4CC(F)C4)nn3C)nc12 +COc1cc2c(cc1OC)C(=O)C(=Cc1cc(C)c(N)c(C)c1)C2 +CCOC(=O)N1C2CCC1CC(c1ccnc3c(-c4ccc5cc[nH]c5c4)c(-c4ccncc4)nn13)C2 +CC(=O)c1nn(CC(=O)N2C(C(=O)NCC3CC3(Cl)Cl)CC3CC32)c2ccc(OCc3ncccc3F)cc12 +NC1=NC(CCc2ccc(Nc3ncc(C4CCC4)cn3)cc2)CO1 +N#Cc1ccc2nc(Nc3ccc(-c4ccccc4)cc3)[nH]c2c1 +Nc1cc(CNC(=O)c2cc(NC(=O)c3cc(-c4ncccc4F)c(Cl)cc3Cl)n(-c3ccccc3)n2)ccn1 +Cc1ccc2c(=O)n(-c3ccccc3)c(C(C)Nc3ncnc(N)c3C#N)nn12 +CC1CN(c2cccc(C(=N)N)c2)C(=O)N(C2CCN(Cc3ccccc3)CC2)C1 +CC(C)(F)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1Nc1cnn(C(F)F)c1 +O=C(CC1CCCCC1)Nc1cccc(OCCCN2CCOCC2)c1 +CCOC(=O)Nc1ccc(Nc2ncnc3cc(OCCN4CCCCC4)c(OC)cc23)cc1C +CCCCCCCCNC(=O)C(Cc1ccc(OCc2ccc3ccccc3n2)cc1)NC(=O)C1CCC(CN)CC1 +Cc1ccc(F)cc1Nc1nc2ccc(N(C)C(=O)C=CCN(C)C)cc2n2cncc12 +CC(C)N(C)Cc1ccn2c(-c3ccnc(NC(C)(C)C)n3)c(-c3ccc(F)cc3)nc2c1 +CC(=O)N1CCN(c2ccnc(-n3ccnc3)n2)C(CC(=O)NCc2ccc3c(c2)OCO3)C1 +COC(=O)c1c(F)cccc1-c1ccc(CNC(=O)CCCc2ccc3cccnc3n2)c(F)c1 +CC(C)COCCCNC(=O)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +OCC(CO)c1ncc(-c2cc(F)cc3c2-c2ccccc2C3(O)C(F)(F)F)o1 +N#Cc1ccc(-c2ccc3cc(CCN4CCCC4CF)ccc3c2)cc1 +O=c1[nH]c2ccc(OC3CCN(c4ccccc4)CC3)cc2c2c1CSCC2 +COc1ccc(-c2nn3c(NC4CCCC4)cccc3c2-c2ccnc(NC3CCCC3)n2)cc1 +CNc1nn2c(NC)cc(C)nc2c1S(=O)(=O)c1ccccc1 +CCN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(Cl)cc2)[nH]c2ccccc12 +CN(C(=O)C=Cc1ccoc1)C1CCC2(O)C3CC4=C(CC(O)CC4)C2(CCN3CC2CC2)C1 +COc1ccc(C2Cc3cc(Cl)ccc3N(CCN(C)C)C(=O)C2C)cc1 +Cc1nc2sc(-c3ccc(F)cc3)nc2c(=O)[nH]1 +O=C(CN1CCN(c2ccnc(NCCc3ccc(Cl)cc3)n2)CC1)N(Cc1ccncc1)CC1CCCO1 +CCCN(CCc1c[nH]c2ccccc12)Cc1ccc(C=CC(=O)NO)cc1 +COCCCc1cc(Br)cc(CN(C(=O)C2CNCCC2c2ccn(C)c(=O)c2)C2CC2)c1 +O=C(NC(Cc1ccccc1)CN(Cc1cnc2ccccc2c1)CC(Cc1ccccc1)NC(=O)OCc1nccs1)OCc1cncs1 +CN(C)CCCNC(=O)c1ccc2[nH]c(=O)c3sc4cc(Br)ccc4c3c2c1 +CC(c1ccc2ncccc2c1)c1nnc2ccc(-c3ccc(S(C)(=O)=O)cc3)nn12 +CC(O)(C=Cc1cccc([N+](=O)[O-])c1)CCC1C(C)(O)CCC2C(C)(C)CCCC21C +Cc1cc(F)ccc1C1CC(NC2CC2)CCN1C(=O)N(C)C(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cn1c(N2CCNC(c3ccc(C#N)cc3)C2)nc(-c2ccncn2)cc1=O +Fc1cccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)c1 +CCc1ncnc(-c2ccc(C(=O)N3CCC4(CCN(C)C4)C3)c(OC)c2)c1C#Cc1ccc(N)nc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NC(C)C(=O)NC1C(=O)N(CC(N)=O)Cc2ccccc2C1C +CCOC(=O)C(O)=CC(=O)c1cn(Cc2c(F)cccc2F)c2cccc(OC)c12 +CCOC(=O)c1c(-c2cccc(-c3ccccc3)c2)[nH]c2cc(OC)c(Cl)cc2c1=O +CNc1cc(Oc2ccc(NC(=S)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2F)ncn1 +CNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC(C)C)ncc1Cl +CSc1cccc(Nc2nc(N)c(N=O)c(OCC3CCCCC3)n2)c1 +CC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(C(F)(F)F)n3)CC3CC32)c2cnccc12 +Cc1cccc(C)c1Nc1ncc(-c2ccc(CN3CCCC3)s2)n2cncc12 +O=C(c1ccc(-c2ccc(O)cc2)o1)N1Cc2c(nc3ccccc3c2O)C1c1ccc2c(c1)OCO2 +CC(O)C#Cc1c(N)ncnc1NC(C)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CCOC5)c4)ccn23)c1 +COc1ccc(N2CC(CN3CCC(O)(c4ccc5c(c4)OC4(CCCC4)O5)CC3)OC2=O)cc1 +O=C(C=Cc1ccccc1Cl)NC1(C(=O)NC(Cc2ccccc2)C(=O)NCC2CCN(CC3CCOCC3)CC2)CCCC1 +CON=Cc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccn3)c2c1 +O=C(Nc1cc(OC(F)(F)F)cc(-c2cccnc2)c1)N1CCc2ccc(CO)cc21 +Cc1ccc(C)c(Nc2nc(NCc3ccco3)c3ccccc3n2)c1 +COC1CCN(c2n[nH]c3cc(NC(=O)NC(COC(F)F)c4ccccc4)ncc23)CC1 +CC(C)CCN(CC(=O)NO)C(=O)N1CCCC1C(=O)Nc1ccc2c(c1)OCO2 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)cc1F +COc1cccc(OC)c1C1CCC(=O)N1Cc1cccc(-c2ccccc2)c1 +N#Cc1ccc(Cn2cncc2CNC2CCN(c3ccccc3Cl)C2=O)cc1 +CC(NC(=O)C1(NC(=O)c2ccno2)COC1)c1ncc(-c2cc(Cl)cc(Cl)c2OCC(F)F)cc1F +COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1 +CN(CCN)C(=O)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(CCCCCCC(=O)c1ccc(-c2ccccc2)cc1)NO +COc1ccc(S(=O)(=O)N(CC(O)CN2C(=O)C3(CCCCC3)OCC2Cc2ccccc2)CC2CCCC2)cc1 +O=C(Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3sccc3n2)cc1)Nc1cccnc1 +CN(C)C(=O)Nc1ccccc1-c1nc(Nc2ccc3[nH]ncc3c2)c2ccccc2n1 +COc1cc(C=CC(=O)NCCCNc2c3c(nc4ccccc24)CCCC3)ccc1OCCO[N+](=O)[O-] +COc1ccccc1N1CCN(CCCCC(=O)NC2CCCc3c(OC)cccc32)CC1 +CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccc(Cl)cc3)C2=O)c(F)c1 +CCCn1c(=O)c2nc(-c3cc(NC(=O)Cc4ccc5c(c4)OCO5)nn3C)[nH]c2n(CCC)c1=O +CN(C)c1ncnc2c1nc(N(C)C)n2Cc1cccc(NC=O)c1 +CCCCCc1nc2cc(C=CC(=O)NO)ccc2n1CCNC(C)C +Cc1cnc2cccc(OCc3c(C)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(N5CCCC5=O)cc4)c3C)c2n1 +CCOC(=O)NC1CCC(NC(=O)c2cc(-c3ccnc(OC)c3)n3ncnc(N)c23)CC1 +CNCC(=O)NC(c1cc(Cl)ccc1N1CCN(C(=O)C(C)Cc2ccc(Cl)cc2)CC1)C(C)C +O=C(c1n[nH]c2c1CN(CC1CC1)CC2)N1CCC(c2cccc(F)c2Cl)CC1 +O=C(Nc1ccc(F)cc1)c1c(Nc2ccccc2)[nH]c(=O)n(O)c1=O +c1ccc2oc(NC3=NCC4(CN5CCC4CC5)N3)nc2c1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccc(C)cc2[nH]1)C(F)(F)F +CN1CCN(CCNc2nc3cc(Cl)c(C#CCCO)cc3nc2NCCN2CCN(C)CC2)CC1 +COc1cc(C2c3cc4c(cc3C(CCN3CCCC3CO)C3COC(=O)C23)OCO4)cc(OC)c1O +Nc1ccc(S(=O)(=O)Nc2cccc(S(N)(=O)=O)c2)cc1 +O=C(NC1CC1)c1ccc(N2CCC(Cc3ccccc3)CC2)nc1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=S)NCC +CS(=O)(=O)N1CCCC(c2csc(-c3cc(N4CCOCC4)ccc3NC(=O)c3ncc[nH]3)n2)C1 +COc1ccc2c(ccn2S(=O)(=O)c2cccc(C(=O)Nc3ccc(Cl)cc3C(=O)O)c2)c1 +CC(C)NC(=O)c1ccc(-c2nc(-c3nnc(Cc4ccc(F)cc4)o3)c(O)c3ncccc23)cc1 +Cc1ccsc1-c1c2c(nn1C)CCc1cnc(Nc3cnn(C)c3)nc1-2 +CC(C(=O)Nc1ccccc1)(C(=O)Nc1ccccc1)c1ccc(C(=O)Nc2ccccc2N)cc1 +c1cc(COc2ccc(C3=NCCN3)cc2)ccc1COc1ccc(C2=NCCN2)cc1 +CC(=O)Nc1nc2ccc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(C(F)(F)F)cc4)c3)cc2s1 +CCC(Nc1c(Nc2cccc(C(=O)NC(C)C)c2O)c(=O)c1=O)c1ccccc1 +O=S(=O)(c1ccccc1)c1cn(C2CCCNC2)c2ccccc12 +CN(CC(CCN1CCC(CCCc2ccccc2)CC1)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 +CCN(C(=O)c1ccc2c(c1)nc(NC(=O)c1ccccc1)n2CCC(N)=O)C1CCCCC1 +CCc1nc(N)nc(N)c1-c1ccc2c(c1)N(CCC(=O)OC)CCC2 +Fc1cc(OC2CC3CCC(C2)N3)cc(-c2ccccc2)c1 +O=C(NC1CCN(CCc2cccc(F)c2)C1)C12CC3CC(CC(C3)C1)C2 +CN(C)CCC(Oc1ccc(C(F)(F)F)cc1)c1ccccc1 +CCOc1ccc2[nH]c3c(NCCN(C)C)ncnc3c2c1 +O=C(CN1CCCC(c2ccccc2)(c2ccccc2)C1=O)N1CCN(Cc2cccc(C(F)(F)F)c2)CC1 +Cc1ccc(C(C)N2CCC3(CCC(=O)CC3)OC2=O)cc1 +NNC(=O)CSc1nnc(Cc2csc(NCCC(=O)O)n2)n1NC(=O)c1ccc(Cl)cc1 +CCC(C)NNC(=O)c1cc(C23CC4CC(CC(C4)C2)C3)c2ccccc2n1 +CCc1cccc(CC)c1NC(=O)NCC1(c2ccccc2)CCCCC1 +C=Cc1ccc(-c2cnccc2C2SCC(=O)N2CC(C)C)cc1 +Nc1ncc(NC(=O)c2c(Cl)ccc3c(Nc4cccc(C(F)(F)F)c4)noc23)cn1 +Cc1ccc(-n2cnc3cc(C(=O)N4CCCCC4)ccc32)cc1 +Nc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccc(N)cc4)s3)s2)cc1 +O=C(O)CNC(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +Cc1cc(CN2CCCC2CN(C)c2nc(N)n3nc(-c4ccco4)nc3n2)no1 +O=C(CCC(NS(=O)(=O)c1ccc(-c2ccccc2)cc1)C(=O)O)NCCc1ccccc1 +CN1CCN(CCCN(C(=O)Nc2ccc(F)c(Cl)c2)C2CCC3(c4cccc(NS(C)(=O)=O)c4)CC23)CC1 +CC1(O)CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)C1 +CC(NC(=O)C(O)C(O)C(=O)N1CCCC1c1csc(N(C)C)n1)c1ccc(-n2cccn2)cc1 +CC12CCC3c4ccc(OS(N)(=O)=O)cc4CCC3C1CC(=O)N(CCCCBr)C2=O +CON=C(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(OC(C)C)cc2n1Cc1ccccn1 +CCOc1cc(CNC2CCCC2)cc(Cl)c1OCc1ccccc1F +Cc1c(P(=S)(c2ccccc2)c2ccccc2)n2ccccc2[n+]1CCCCc1ccccc1 +CNC(=O)Cc1ccc(Cl)c(F)c1-n1c(C2CCCCC2)nc(-c2nnc(N)o2)c1-c1ccc(F)c(Cl)c1 +O=c1c2ccccc2nc(-c2ccccc2O)n1CCc1cccc(Cl)c1 +CCNC(=O)c1ccc(C(C2=CN(O)C=CC2)=C2CC3CCC(C2)N3Cc2ccoc2)cc1 +COCCN1CCN(c2ncc(-c3cccc(C(C)Nc4cc(-c5ccc6occ(C)c6c5)nc(C)n4)c3)cn2)CC1 +O=c1[nH]c(-c2ccc(Cl)cc2Cl)nc2c1oc1ccc(Br)cc12 +Cc1cccc(N2CCN(Cc3ccc4oc(=O)ccc4c3)CC2)c1 +COc1ccc(C(O)=C(C#N)C(=NC2CCCCN(CC(=O)N3CCCC3)C2=O)Nc2ccc3oc(C)cc3c2)cc1 +CC(=O)N1CCN(C(=O)c2cc(Sc3cnc(NC(=O)c4ccc(N(C)C)cc4)s3)ccc2Cl)CC1 +CN1CCCc2ccc(Nc3nc(N4CCCCC4)nc4c3CCN(c3ncccc3C(F)(F)F)CC4)cc21 +CN(CCCN1C(=O)C2Cc3ccccc3CN2C1=O)Cc1ccccc1 +CNS(=O)(=O)c1ccc(N(C)C)c(Nc2ncnc(Nc3ccc(Cl)cc3)n2)c1 +CC(C)n1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(NC6CCC(O)CC6)c5)nccc34)cn2)cn1 +CN(CCCNC(=O)c1cccc2cc3cc(Br)ccc3nc12)CCCNC(=O)c1cccc2cc3cc(Br)ccc3nc12 +Nc1noc2ccc(-c3cc(Cl)ccc3Oc3cc(F)c(S(=O)(=O)Nc4ncns4)cc3F)cc12 +CC(C)(O)c1cnn2c(-c3ccc(F)c(-c4ncccc4C#N)c3)cnc2n1 +CCCCCCCCCCCCCCC1CC(O)(P(C)(=O)O)CCN1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)NCc2ccccc2)c1 +CCCOC(Cc1ccc(NC(=O)CCCCC2CCSS2)cc1)C(=O)O +COc1cccc(CNCCCNc2ccnc3cc(CCC(C)C)ccc23)c1O +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NC(C(F)(F)F)C(F)(F)F)c12 +COc1ccc(S(=O)(=O)N(Cc2cccnc2)c2c(C)cc(-c3ccccc3)cc2C(=O)NO)cc1 +Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CCC(OCC(C)(F)F)CC1 +CCCS(=O)(=O)c1cc(Cl)ccc1S(=O)(=O)c1ccc(C(C)NS(C)(=O)=O)cc1 +CC(NC(=O)C(F)F)c1ccc(OC2CCN(c3ccnc(OCC4CC4)c3)C2)cc1 +NCc1ccc(NC(CP(=O)(O)C(N)CCc2ccccc2)C(=O)O)cc1 +CCOC(=O)N1CC2CCC(C1)C2NCCNC(=O)c1cccc(OC)c1 +NC(=O)N1CCCc2cc(-c3cncc(COCC(=O)N4CCC5(CC4)CC5)c3)cnc21 +CCc1cc(-c2c(-c3ccc(F)cc3)nc(C(C)C)n2C=CC(O)CC(O)CC(=O)O)cc(CC)c1F +CCN1C(=O)c2nc(-c3ccc(F)cc3)n(Cc3cc(F)cc(F)c3)c2N2CC(C(C)C)N=C12 +Cc1[nH]nc2c1C(c1ccc(Cl)cc1)N(c1ccc(=O)n(C)c1)C2=O +COc1ccc2c3c(c4cc(OC)c(O)cc4c2c1)CC1CCCN1C3 +COC1CCC2(CC1)Cc1ccc(Br)cc1C21N=C(N)N(C)C1=O +COc1ccc(-c2cccn3nc(Nc4ccc(N5CCOCC5)cc4)nc23)cn1 +O=C(NC1CCC(CCN2CCN(c3cccc(Cl)c3)CC2)CC1)C1CCCCC1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]nc(C#N)c1Cl +O=C(NS(=O)(=O)N1CC(F)C1)c1cc(Cl)c(OC2CC3CC3C2)cc1F +COc1cc(-c2cnc(N)c(-c3cc(OC)c(OC)c(OC)c3)c2)ccc1O +CC(C)(O)CCc1c(O)cc(O)c2c1OC(c1cc3c(cc1O)OC(C)(C)C=C3)CC2=O +CC(C)=CCN1CCn2c(=O)[nH]c3ccc(Cl)c(c32)C1C +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2noc(C(F)F)n2)CC1c1ccccc1F +O=C(Nc1cn(CC(=O)N2CCC(N3CCCC3)CC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +O=c1c2c(nc3ccccn32)n(Cc2ccccc2)c(=O)n1CC1CCCCC1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCC(N4CCCC4)CC3)cc2c1=O +CCN(CC)C(=O)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(OS(C)(=O)=O)c(=O)n1C +CCc1cc(OC)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1 +Cc1ccc(C=Nn2c(S)nnc2-c2cccc(Cl)c2)o1 +CC1(C)C2CC=C(COc3ccc4c5c(c(=O)oc4c3)CCC5)C1C2 +CN1CCC(N2CCN(C(=O)CN(C)C(=O)c3nc4ccccc4n3Cc3ccccc3)CC2)CC1 +Cn1c(-c2ccccn2)c(C2CCCCC2)c2ccc(C(=O)NC3(C(=O)Nc4ccc(C(=O)O)cc4)CCC3)cc21 +O=C(c1ccsc1)c1nc(C(F)(F)F)nc2ccsc12 +CCc1cc2c(N3CCN(C(=O)c4ccc(-c5ccccc5)cc4)CC3)nc(NCCCO)nc2s1 +O=C(NS(=O)(=O)c1ccc2ccoc2c1)c1ccc(Cl)cc1Cl +Cc1c(Cc2cccnc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O +COC1CCC2(CC1)Cc1ccc(OC(C)C)cc1C21N=C(N)N(C)C1=O +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1=O)NCc1ccccc1-c1ncc[nH]1 +Cn1cnc(-c2ccc3[nH]nc(Cc4ccc(-c5cnn(C)c5)cc4)c3c2)c1 +Cc1ncc(C)n2nc(CCc3ccc4cc(C#N)c(Cl)cc4n3)nc12 +CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(CNC3COC3)n1CCO2 +CC(C)(C)C(=O)NC(C(=O)NO)c1ccc(-c2ccccc2F)cc1 +COc1ccnc(C[S+]([O-])c2nc3cc(OC(F)(F)C(F)F)ccc3[nH]2)c1C +CC(O)CN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCC1 +Cc1ccc(NC(=O)c2nc(C(F)(F)F)[nH]c2-c2ccc(F)c(Cl)c2)cc1Nc1ccc2ncn(C)c(=O)c2c1 +Nc1nc2c(c(=O)[nH]1)CC(CCc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)CN2 +CC12C=CC(=O)C=C1C=C(Cc1ccccc1)C1C2CCC2(C)C(=O)CCC12 +C=CC(=O)Nc1cccc(N2C(=O)N(C)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4C)nc32)c1 +COCCN(CCOC)c1nc(C)nc2c1n(C)c(=O)n2-c1c(C)cc(C)cc1C +Fc1ccc2c(C3=CCN(CCOc4cccc5c4OCCO5)CC3)c[nH]c2c1 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+COc1ncc(-c2nc3c(n2C2CCC2)C(c2ccc(C#N)cc2)N(c2ccc(F)c(Cl)c2)C3=O)c(OC)n1 +Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4CCC(C(=O)NC(C)(C)C)C4)cc3)nn3cccc23)n[nH]1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(F)c(O)c2)c1 +CN1C=C(c2ccc3ccccc3n2)C(c2c[nH]c3ccccc23)c2ccccc21 +CC(C)CCN(CCC(C)C)C(=O)c1ccc2nc(Nc3cccc4[nH]ccc34)n(CCCN3CCCCC3)c2c1 +O=C(O)c1cc(-c2ccc(C3CCNCC3)cc2)c2ccc(-c3ccc(C(F)(F)F)cc3)cc2c1 +c1ccc(CN2CCC(CCNc3ccc(-c4ccc5ccccc5c4)nn3)CC2)cc1 +CCc1cc2c(SCC(=O)N(CC)c3c(N)n(Cc4ccccc4)c(=O)[nH]c3=O)ncnc2s1 +N#CCN(CC(=O)N1CCCC(c2ccccc2)C1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +NC(=O)c1c(N2CCCC2)nc2sc3ccccc3n2c1=O +CN(C)C(=O)n1nnc(-c2ccc(Oc3cccc(Cl)c3)cc2)n1 +CC(C)(CC(O)(Cc1cc2cc(S(C)(=O)=O)ncc2[nH]1)C(F)(F)F)c1ccc(Cl)cc1C(N)=O +O=C(Nc1ccccc1)N1CC(Oc2ccc(-c3ccccc3)cc2)C1 +O=C(Nc1cccc(OC(=O)c2ccccc2)c1)NC12CC3CC(CC(C3)C1)C2 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2cnccc2OC)s1 +COc1ccc(N(C(=O)Nc2ccc3nc(-c4cc(-c5cnn(C6CCNCC6)c5)cnc4N)oc3c2)c2ccccc2)cc1 +OC1CCC(Nc2cc(-c3cccc(NC4CCOCC4)n3)c(Cl)cn2)CC1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CCCCc5ccccc54)ncc23)ccn1 +CC(=O)NC(C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1)CO +CCC(=O)Nc1cc(Cl)c(Oc2ccc(O)c(-c3ccc(C(N)=O)cc3)c2)c(Cl)c1 +Cc1noc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)n1 +NC1CCCN(c2cncc(-c3cc4c(-c5ccccc5F)n[nH]c4cn3)c2)C1 +CCOC(=O)c1ccc(Nc2cc(C3CCCNC3)nc3c(-c4cnn(C)c4)cnn23)cc1 +CC(c1ccc(N(C)C(=O)c2ccc(F)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +Cc1ccc(NC(=O)c2cc(C(C)(C)C)nn2C)cc1Nc1nc2ccccc2n1-c1cc(N)ncn1 +CC(C)(NC(=O)c1ccc(OC(F)(F)F)cc1)C(=O)Nc1nc(-c2ccc(F)cc2)c(Oc2ccc(F)cc2)s1 +O=C(Nc1ccc(CO)cc1)Nc1ccc(-c2nc(N3CCOCC3)c3ncccc3n2)cc1 +COc1cc(-c2cc(Cl)cnc2OC)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3cccnn3)ccc21 +CC=CCN1C2CCC1CC(N(c1ccc(C(=O)N(CC)CC)cc1)c1cccc(OC)c1)C2 +O=C(CC(CCCC1CCCCC1)c1nc(CNC2CCC2)no1)NO +CC1CCCN1CCc1ccc(-c2ccc(S(=O)(=O)CC3CCOCC3)cc2)cc1 +Cn1cc(Cn2cc(-c3ccc(Cl)c(OC(F)F)c3)cn2)cn1 +CC1CCC2C(C)(C)C3CC12CCC3(C)OC(=O)C(C)(C)c1cccnc1 +COc1cc(C(=O)NC2CCCN(Cc3ccc4c(c3)OCO4)C2)cc(OC)c1C +COc1cc(-c2n[nH]c3cc(NC(=O)NC(C)c4ccc(F)cc4)ncc23)ccn1 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+c1ccc2c(c1)CC(N1CCN(c3cccc4c3OCCO4)CC1)C2 +O=C(O)CN1C(=O)C(=Cc2cc3ccccc3cc2Br)SC1=S +CCCN(CCN1CCN(c2ccc(-c3ccc(OC)cc3)cc2)CC1)C1CCc2nc(N)sc2C1 +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCN2CCCC2)CC1 +Cc1oc2c(O)c3c(c(O)c2c1C(=O)NC1CCNCC1)C(=O)c1ccccc1C3=O +CC1CN(CC2(C(N)=O)CCC2)CCN1S(=O)(=O)c1ccc(C(C)(O)C(F)(F)F)cc1 +CN(c1cc(C=CC2CC2)cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CC2)c1)S(C)(=O)=O +c1cn(-c2ccc(NC3CCCN(Cc4ccc5c(c4)OCO5)C3)cc2)cn1 +Cc1ccc(ON2C(=O)C(NC(=O)OCCCCC3CCCCC3)C2C)cc1 +NC(=O)c1c(NC(=O)Cn2nc(C(F)(F)F)c3cnccc32)sc2c1CCCC2 +CN(C)CCCOc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 +COc1ccc2c(c1)CN(C(=O)CCN1CCCCC1)CCS2 +Nc1nc(-c2ccccc2)c2c(n1)-c1cc(Cc3cccnc3)ccc1C2=O +OC1(c2ccc3c(c2)OCO3)CCC(N2CCN(Cc3cccc(Br)c3)CC2)CC1 +c1ccc(C2CN3CCCC3c3[nH]c4ccccc4c32)cc1 +COc1ccc2nc(C)c3c(C)nc(-c4ccccc4Cl)n3c2n1 +c1ccc2[nH]c(-c3ccc(OCCCCCOc4ccc(-c5nc6ccccc6[nH]5)cc4)cc3)nc2c1 +Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ccc(-c3cncnc3)cc1)C(=O)N2c1cc(O)ncn1 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4COCc4ccc(C(C)(C)C)cc4)C(C2)N(CC2CC2)CCC315 +COc1c(C(=O)NCCN2CCCC2)sc2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3cccc(N(C)C)c3)nc12 +CNc1ccc(C=Cc2ccc(OCC(CO)CO)cc2)cc1 +Cc1cncc(-c2cc3c(cn2)cnn3-c2cccc(C3=CCNCC3)n2)n1 +CC(C)Cc1ncccc1COc1c(Cl)cc(-c2ccnc(N3CCNCC3)c2)cc1Cl +CCCCc1nc2c(C)cc(-c3ccccn3)cc2n1Cc1ccc2c(ccn2-c2ccccc2C(=O)O)c1 +CN(C)Cc1nccn1-c1ccc(N2CCC(NS(=O)(=O)C=Cc3ccc(Cl)s3)C2=O)c(F)c1 +COc1cccc(Oc2cccc3c2c(C=CC(=O)NS(=O)(=O)c2ccc(F)c(F)c2)cn3C)c1 +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)N(C)C(C)C)c12 +COc1ccc(NCc2ccc(C(=O)Nc3ccccc3N)cc2)cc1 +CC(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CC(C)(C)C)NC(=O)N1CCOCC1 +CC(=O)OC1(C(C)(C)C)CCN2CC(c3ccc(Cl)cc3)CCC2C1 +Cc1cc(O)ccc1NC(=O)c1cc(N(C)C2CCCCC2)ncn1 +Cn1c(Cc2nc3cc(F)ccc3[nH]2)nc(N2CCOCC2)cc1=O +Cc1cc(COc2ccc(N3CCC(N)(CC(=O)NO)C3=O)cc2)c2ccccc2n1 +CN(C)C(=O)Cn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CCC(CC)C(=O)Nc1ccc(C(=O)NC2(C(=O)NCC#N)CCCCC2)cc1F +O=c1[nH]cnc2c1ncn2CCN(CCP(=O)(O)O)CCP(=O)(O)O +CCc1ncnc(-c2cnc3ccccc3c2)c1C#Cc1ccc(N)nc1 +CC(C)(C)c1cccc2ncn(CC(=O)CC3NCCCC3O)c(=O)c12 +O=C(Cc1cc(Cl)cc(Cl)c1)NC1N=C(c2ccccc2)c2ccccc2N(CC(F)(F)F)C1=O +c1ccc(-c2n[nH]cc2-c2ccnc(-c3ccc(CNC4CCCOC4)cc3)c2)nc1 +C=CC(OCC)C(NC(C)=O)C1NC(C(=O)O)CC1C=CC +N=c1ccc(-c2ccc(Cl)cc2)nn1Cc1cc(O)no1 +CC(C)C(N)C(=O)N1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 +O=C(NN=Cc1ccc([N+](=O)[O-])o1)C1CC1 +O=C(NCc1ccc(C(F)(F)F)cc1Cl)C1COc2ncccc21 +CN1CCN(c2ccc(-c3cc4c(Cl)cc(C(N)=O)nc4n3C)cc2)CC1 +O=C(c1ccccc1)c1cc2ncnc(Nc3ccc4[nH]ccc4c3)c2s1 +Cc1nc(NCCNC(=O)C2CC2)nc2ccc(NC(=O)C=Cc3ccc(OC(F)(F)F)cc3)cc12 +CCOC(=O)c1[nH]c2ccc(Cl)cc2c1Sc1cc(OC)c(OC)c(OC)c1 +O=C(O)c1cccc2[nH]c(-c3c(F)c(F)c(-c4ccccc4)c(F)c3F)nc12 +CC(c1ccc(C(=O)NCCC(=O)O)cc1)N1C(=O)C(c2cc(Cl)ccc2F)=NC12CCC(C(C)(C)C)CC2 +CC(C)(C)OC(=O)n1c(-c2ccc3c(c2)CC(NS(=O)(=O)c2ccccc2)C3)cc2ccccc21 +CCOc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Sc2ccccc2OC)CC1 +OC1(c2cccc(COc3ccc4c(-c5ccoc5)cncc4c3)n2)CC2COC(C1)O2 +CNC(=O)C1CCN(C(=O)CCC(=O)N(CC(C)(C)C)c2ccc(Cl)cc2C(O)c2ccccc2Cl)CC1 +O=C(Nc1ccc2cc(C(=O)NO)sc2c1)c1ccc2ccccc2c1 +NCCCCCCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +CC(NCC(=O)N1CCN(C(C#N)c2cccnc2)CC1)c1ccccc1 +O=C(NCCN1CCCC1)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 +NCC(CC(=O)O)c1ccc(Cl)c(OCc2cc[n+]([O-])cc2)c1 +CC(=O)OCC1=C(C)CC(C(C)C2CCC3C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC23C)OC1=O +Cc1cc(NC(=O)Nc2cc(C(C)(F)F)ccc2F)ccc1Oc1ccnc(NC(=O)C2CC2)c1 +COc1ccc(-n2nc3c(NS(C)(=O)=O)nc4ccccc4n3c2=O)cc1 +CN(C)c1ccc(Cc2cccc(-c3c(O)c4ccc(Cl)cc4[nH]c3=O)c2)cc1 +O=S(=O)(c1ccc(Cl)cc1)N(Cc1ccc(N2CCCCC2)cc1)c1ccccc1 +CCOc1c(Br)cc(C)cc1CNCCCNc1cc(O)c2ccccc2n1 +NC(=O)N1CC2CC(C1)CN(C(=O)CN1CCCC(NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C1=O)C2 +Cc1cc(NCCN(C)C)cc(C)c1-c1cnnc(NCc2nc3cc(O)ccc3s2)n1 +N#Cc1ccc(-c2ccc(S(=O)(=O)Nc3ccc4ccccc4n3)cc2)cc1 +O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3ncco3)ccc1-2 +CCSC(=S)SCC(=O)c1cccc(C(=O)Nc2ccccc2)c1 +COc1cccc(F)c1CNC(=O)Nc1cc2[nH]nc(-c3ccnc(C)c3)c2cn1 +O=C(NC1CC2c3[nH]c4ccccc4c3CC(C(=O)NC(Cc3ccccc3)C(=O)O)N2C1=O)OCc1ccccc1 +CN1CCC(N2CC3CCN(S(=O)(=O)c4ccc(Cl)cc4)CC3Oc3c(NC(=O)C4CC4)cccc3C2=O)CC1 +CCCNCC(O)COc1ccc(OCc2ccccc2)cc1C(=O)CCc1ccccc1 +Nc1nc(COc2cccc(F)c2)nc2c1nnn2CC1CCCO1 +O=C(c1cc(O)c(O)c([N+](=O)[O-])c1)c1ccccc1F +CCn1c(=O)n(Cc2ccc(C(=O)Nc3ccccc3N)cc2)c(=O)c2ccccc21 +CCn1c(=O)c2c(nc3n2CCCN3CCc2ccc(OCCN3CCOCC3)cc2)n(CC)c1=O +COc1ccc(-c2nc3c(=O)[nH]c(C)nc3s2)cc1 +CC1(COc2cccc(-c3ccc(F)nc3F)n2)CCn2cc([N+](=O)[O-])nc2O1 +COC(=O)c1cccc(-c2cnc(C(=O)CCc3ccc(COc4ccccc4)cc3)o2)n1 +O=C(Nc1ccc(F)cc1F)C1C(=O)N2c3ccccc3Oc3cccc1c32 +N#Cc1cc(C#Cc2ccccn2)ccc1-c1ccc(F)cc1 +CCOC(=O)C(C#N)=CC=C1C=CN(CC(=O)N2c3ccccc3Sc3ccccc32)C=C1 +Cc1cc(-c2nnn(CC3CCC(C(=O)O)CC3)n2)cc(C(=O)NCc2cccc(F)c2)n1 +COc1ccc(C(O)=CC(=O)C(=O)O)cc1Cc1ccccc1 +NC1CCN(c2nc(-c3ccncc3)cnc2N2CCCC2)CC1 +NC(=O)c1ccc(F)c2c1CC(N(CCCCn1ccc3c(F)cccc31)C1CCC1)CO2 +COc1ccc(Br)cc1S(=O)(=O)N1CCN(C(=O)Cn2c(=O)oc3ccc(Cl)cc32)C(CN2CCCC2)C1 +O=C1NC(=S)NC(=O)C1=Cc1ccc(-c2ccc3c(c2)COC3=O)s1 +CCOC(=O)C1=CCCCC1S(=O)(=O)Cc1ccccc1Cl +O=C1OC2(CCC(C(=O)Nc3cc(-c4ccccc4)on3)CC2)c2cccnc21 +COc1c(N(C)C(=O)CNC(=O)C=Cc2ccc(C(F)(F)F)cc2)ccc(Cl)c1COc1cccc2ccc(C)nc12 +O=C(CN1C(=O)NC(CCCNC2=NCCN2)C1=O)NCC(NC(=O)OCc1ccccc1)C(=O)O +Cc1nc(-c2ccc(F)cc2Cl)c2c(N3CCc4nc(C5CC5)ncc4C3)ncnn12 +Cc1ccc(C(=O)ON=Cc2c(N3CCOCC3)n(C)c3ccccc23)cc1 +CC(C)C(=O)Nc1nc2ccc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)cc2[nH]1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC2CCN(C(=O)C3CCCN3)CC2)c2ccccc12 +O=C(NC1CCCNC1)c1ccc(O)c2[nH]c(C3CC3)nc12 +NC1=NCC(Cc2ccc(OC(F)(F)F)cc2)C(N)=N1 +Oc1n[nH]c(CN2CCOC3(CCC(c4ccccc4)CO3)C2c2ccccc2)n1 +COCCN(C(S)=Nc1c(C)cc(C)cc1C)C(C)c1cccnc1 +O=C(NO)C1(S(=O)(=O)c2ccc(OCCCc3nnnn3-c3ccc(OC(F)(F)F)cc3)cc2)CCOCC1 +CC(C)Oc1cccc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)c1 +CS(=O)(=O)c1ccc(C=C(c2ccccc2)c2ccc(F)c(F)c2)cc1 +COc1ccc(OCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 +C=C(CCCCC)c1c(C)[nH]c2cc(OC)c(Cl)cc2c1=O +c1ccc2c(c1)Cc1cc(OC3CN4CCC3CC4)ccc1-2 +CCOc1ccc(N2CCN(c3noc(C4(NC(C)=O)CCC4)n3)C(C)C2)c(C)c1 +CNC(=O)C12CC1C(n1cnc3c(NC4CC4c4ccccc4)nc(Cl)nc31)C(O)C2O +O=c1cc(-c2[nH]c(-c3ccc(-c4cn(CCO)nn4)cc3)nc2-c2ccc(F)cc2)cc[nH]1 +O=C(C=Cc1cccc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)c1)NO +CC(NC(=O)Nc1cc2[nH]nc(C3CC3)c2cn1)c1ccc(Cl)cc1 +CC1(C)CC(CCNc2ccc(Cl)cc2)(c2ccccc2)CCO1 +Cc1ccc(NC(=O)c2cccc(-n3cc(NC(=O)Nc4ccccc4F)cn3)c2)cn1 +c1ccc(CN2CCC(CCc3nsc4ccccc34)CC2)cc1 +O=C(O)C(c1ccccc1)N1CCCC(CN2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)C1 +O=C1CCCC(=O)C1C(=O)c1ccc(C(F)(F)F)cc1[N+](=O)[O-] +COc1cccc2c(CNC3(c4nc(-c5ccc(C)cc5)c[nH]4)CCCC3)c[nH]c12 +CC(NC(=O)Nc1cc2[nH]nc(-c3ccn4ncnc4c3)c2cn1)c1ccccc1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CN2)c1C +O=C(Oc1ccc2[nH]c(C(=O)c3cc4ccccc4[nH]3)cc2c1)c1ccc2ccccc2n1 +CCOc1cc(NC(=O)C2(NC(=O)c3ccc4c5c(n(C)c4c3)CCCC53CCCCC3)CCC2)ccc1C=CC(=O)O +CC(CCc1ccc(C2=CCCCC2)cc1)(C(=O)NO)S(C)(=O)=O +Oc1ccc2c3c1OC1c4[nH]c5ccc(C=Cc6ccccn6)cc5c4CC4(O)C(C2)N(CC2CC2)CCC314 +Cc1ccc(Cl)cc1N=C1C=C(NS(=O)(=O)c2cccs2)c2ccccc2C1=O +C=CCC(NC(=O)NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)C(=O)O +CN(Cc1ccc2c(c1)[nH]c(=NC(=O)c1ccc(-c3cn[nH]c3)s1)n2CC(C)(C)O)c1ccccc1 +CN1CC(n2cnc3ccc(-c4cccc(OCC(O)CN5CCc6ccccc6C5)c4)cc32)C1 +O=C(O)CC1CCC2(CC1)CCN(c1cc(F)cc(Cl)c1F)CC2 +O=C1OC2(CCC(CNc3ccc(-c4ccccc4F)nn3)CC2)CN1c1cccnn1 +CCC=CC(CC)CC1(CC)C=C(CC)C(=CC(=O)OC)O1 +CC1CN(c2sc(CN(C)C)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21 +CCOc1cc(=O)n(C)cc1-c1cc(N(Cc2ccccc2Cl)S(=O)(=O)Cc2ccccc2)ccc1Oc1ccc(F)cc1F +COc1cc(OC)cc(C(=O)NCC(=O)NC(C)c2ccccc2)c1 +CN(C)CCCn1c(NC(=O)c2ccc3cc4n(c3c2)CC2(CC2)CNC4=O)nc2ccccc21 +O=C1SCCc2nc(-c3ccc(C(F)(F)F)cc3)[nH]c(=O)c21 +NC(=S)Nc1cccc(OCCCCCN2CCN(c3ccc(Cl)cc3)C2=S)c1 +O=C(O)CC(Cc1cc(OCCc2ccc3c(n2)NCCC3)no1)c1cnc(-c2ccc(Cl)cc2)s1 +Cc1oc(-c2ccccc2)nc1COc1ccc(Cc2ccc(OC(C)C(=O)O)cc2)cc1 +CC1(N2CCC(N(c3ccccc3)c3cccnc3)CC2)CCN(C(=O)c2cccc3ccccc23)CC1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(=O)Cc3ccc(F)cc3)c2)[nH]1 +C=CCCC12CC1(C(=O)OCC)C(=O)Nc1ccc(Br)cc12 +Cc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccccc2[N+](=O)[O-])c(C)c1 +CCS(=O)(=O)c1ccc2[nH]c(-c3cccc(-c4ccccc4)c3C)nc2c1 +CCCN(C)c1nccc(N2CCC(Oc3ccc(C(C)C(=O)NCC)cc3)C2)n1 +N#Cc1c(-c2ccc(C(F)(F)F)cc2)cc(NCCN2CCCC2)n2c1nc1ccccc12 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(F)cc1Oc1ccc2cc(C#N)ccc2c1Br +CCOC(=O)c1[nH]c2cc(Cl)ccc2c1C(C(=O)NC(C)(C)C)N(C=O)Cc1cc(F)c(F)c(F)c1F +COc1ccccc1N1CCN(CCN2C(=O)NC3c4ccccc4N(C)C3C2=O)CC1 +CC(C)C(C)(c1ccc(-c2cnc(N)nc2)cc1)c1noc(N2CCC(O)CC2)n1 +CCN1CCN(c2cc(C)c3cc(NC(=O)CCC(=O)Nc4ccc(F)c(Cl)c4)ccc3n2)CC1 +CCC(COCC1CC1)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(=NOCC(C)(C)O)C5)cn3)n2)s1 +CC(C)CC(NC(=O)Cc1ccc2ccccc2c1)C(=O)NC1CC(=O)OC1O +O=C(Cc1cc2ccccc2cn1)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1 +N#CN=C(NCCCc1ccccc1)NCCCc1c[nH]cn1 +COc1cccc2c1[nH]c1c3ccncc3cc(C(N)=O)c21 +COc1cc(-c2ccc(NC(C)c3ccc(F)cc3)nc2)ccc1-n1cnc(C)c1 +Cn1nc(-c2ccncc2)cc1NC(=O)C(Cc1ccccc1)NCC(=O)O +CN1C(=O)C=CC2(C)C3CCC4(C)C(O)CCC4C3CCC12 +CCCn1c(=O)c2c(nc3[nH]c(C)cn32)n(Cc2cccnc2)c1=O +O=C(c1cccc(F)c1F)N1CCc2nc(COc3cccc(F)c3)oc2C1 +NC(=O)c1ccc(-c2nc(-c3ccccn3)c(-c3ccc4c(c3)OCO4)[nH]2)cc1 +COc1cc(OC)cc(N2CCN(C(=O)Nc3nc4cc(C)ccc4nc3OC)CC2)c1 +COc1cc(=O)oc2cc(OCCCN3CCN(c4ncccn4)CC3)ccc12 +C[Si](C)(C)C#Cc1cn(C2OC(CO)C(O)C2O)c(=O)[nH]c1=O +COc1cc2c(cc1O)C(C)N(Cc1cccc(O)c1OC)CC2 +CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nc2ccccc2n1-c1ccccc1N(C)C +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)NCCC(=O)O)cc12 +COc1ccc(Cn2c(C(Cc3ccccc3)NC(C)=O)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)CO)cc1 +CC(C)C(CO)NCc1nc(-c2ccc(F)c(Cl)c2)ccc1F +O=C(Nc1ccc(Cl)cc1)C1CN(C(=O)c2cccc(-c3cccnc3)c2)CC(F)(F)C1 +Cc1ccc(-c2nn(-c3ccccc3)cc2-c2nc3ccccc3[nH]2)cc1 +COc1cc(OC)cc(N(CCN2CCCC(N)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CCC(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)(Oc1ccccc1)C(=O)O +COC(=O)C(C)CNP(=O)(Oc1ccccc1)OC1CC(n2cnc3c(N)ncnc32)CO1 +Cc1nc2c(OC(F)F)cccc2n1-c1ccc(C(=O)NC2CC2)s1 +CCC1CN(c2nc(N)c(C(=O)NCCS(C)(=O)=O)nc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +CC(C)(Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1)C(=O)O +CCCCCCCCn1cc(CN)c2cc(-c3cccc(C)c3)ccc21 +O=C(CCCCCCC(=O)NCc1ccc2ccccc2n1)NO +O=C1NN(c2ccc(I)cc2)C(=O)C1=Cc1cc2c(cc1Br)OCO2 +Cc1ccc(C)c(NS(=O)(=O)c2cc(C(=O)Nc3ccccc3-c3ccccc3)ccc2Cl)c1 +Oc1nc2c(c3nc(-c4ccccc4F)nn13)CCCCC2 +CCCc1nn2ccc(C(=O)NC(CC)c3ccccc3)cc2c1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(F)c(C)n3)C2)cc1 +COCOc1cc(OC)ccc1C(=O)CCC(=O)NC(Cc1ccccc1)C(=O)C(N)=O +O=C(CC1SC(c2ccc(Cl)cc2Cl)N(CC(=O)NCCCN2CCOCC2)C1=O)NCc1csc2ccccc12 +CCN(CC)C(=O)c1ncc(C2=CC3(CCNCC3)Oc3ccccc32)cn1 +O=c1cc(Cn2ccnc2)c2ccc(Oc3ccc(Cl)cc3)cc2o1 +c1ccc(Nc2nc3ccccc3c3[nH]c(C4CCCC4)nc23)cc1 +Cc1cc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5ccc(CN)cc5)nc34)CC2)no1 +CC1CN(C(C)CO)C(=O)c2cc(NC(=O)C3CCCCC3)ccc2OC1CN(C)S(=O)(=O)c1ccccc1Cl +CCCc1c(OCCCOc2cc(O)c(C(C)=O)cc2CC)cccc1Oc1ccccc1C(=O)O +COc1cc2nnc(C(N)=O)c(Nc3ccc(C)cc3F)c2cc1N1CC(C)NC(C)C1 +Brc1ccc(Cn2ccc3nc(C=Cc4ccccc4)nc-3c2)cc1 +CN(C)C1CCN(c2ccc(N3Cc4cn(-c5ccc(Cl)cc5)nc4C3=O)cn2)C1 +O=C(Nc1cc(Cl)ccc1C1CCCCC1)c1cnn2cccnc12 +CCCN(CC1CC1)C(=O)c1c(CC)nc2n(-c3c(C)cc(C)cc3C)c3ccc(F)cc3n12 +COc1cc(Oc2ccccc2)ccc1-c1nc(C2CCC2)n2ccnc(N)c12 +O=C(Nc1ccc(NC(=O)N2Cc3ccncc3C2)cc1)c1cncs1 +N#Cc1ccc(Oc2cccnc2)c(Oc2cccc(Cl)c2)c1 +CC12CCC(O)CC1CCC1CC3(C)C(CCC34CO4)CC12 +CN1CCN(Cc2cn(S(=O)(=O)c3ccc(F)cc3)c3ccccc23)CC1 +Oc1cccc(-c2nc(N3CCOCC3)c3[nH]cc(C4CCN(Cc5ccc(F)cc5)CC4)c3n2)c1 +CC1CN(c2nnc(-c3ccc(C(F)(F)F)cc3)c3ccccc23)CCN1C(=O)c1ccccc1 +CCCCCCCCC(C)(C)c1cc(=O)c2cc(OS(N)(=O)=O)ccc2o1 +CCNC(=O)Nc1nc2cc(-c3ccn(CCOC)c(=O)c3)c(OC3CCOC3)nc2s1 +COc1cc2c(cc1N1CC(C)NC(C)C1)N(S(=O)(=O)c1ccc3ccccc3c1)CC2 +CC1(NC(=O)CBr)CCC(C(C)(C)NCC(O)COc2cccc3[nH]ccc23)CC1 +C#CCn1c(-c2ccco2)nc2c(N)nc(C#CC3(O)CCCCC3)nc21 +CCCOc1ccc(CC(Cc2ccccc2)C(=O)O)cc1CNC(=O)c1ccc(N2CCCC(C)(C)C2)cc1 +CC(C(c1ccc2cc(OCC(C)(C)C)ccc2c1)n1ccnc1)N(C)C +Cc1c(F)ccc(C(=O)Nc2cc(-c3ccc(F)cc3)ccc2N2CCN(C)CC2)c1Cl +COc1cc(C(=O)NCc2ccc(F)cc2Cl)ccc1-c1cn[nH]c1 +Cc1cccc(CN2CCC3(CC2)CCN(C(=O)c2ccccc2)CC3)c1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(N2CCOCC2)cc1F +COc1cc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc(OC)c1 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+O=C(Nc1ccncc1)Nc1ccc(-c2nc(N3CCOCC3)c3ccn(CC(F)(F)F)c3n2)cc1 +CN1CCN(c2ccc(Nc3nc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)cc2)CC1 +Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1cnc(N)cn1 +O=[N+]([O-])c1cccc2c(NCCCCCCCCNc3c4c(nc5ccccc35)CCCC4)c3c(nc12)CCCC3 +Cn1c(SCCCN2CCOC(c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccncc1 +CC1=CCC2C(C1)c1c(O)cc(C(C)(C)c3cccc(Cl)c3)cc1OC2(C)C +Cc1ccccc1N1CC(C(=O)Nc2cccc(C(F)(F)F)c2)CC1=O +CCCOCCn1c(=O)c(N2CC3CC2CN3)nc2cnc(-c3ccc(OC)nc3)cc21 +CC(C)NC(=O)c1cc(-c2ccccc2)nc2c1cnn2Cc1ccncc1 +O=C(NCCCCN1CCCCC1)Nc1ccc(-c2ccccn2)nc1 +COc1ccc(S(=O)(=O)N2CCCc3cc(-c4cccnc4)ccc32)cc1 +CCCS(=O)(=O)NC1CC(N(C)c2ncnc3[nH]ccc23)C1 +CC(C)CCN1CN(c2ccccc2)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O +CCNc1nnc(-c2ccc(C#CC3(CN4Cc5ccc(OC)cc5C4=O)NC(=O)NC3=O)cc2)o1 +CC(C)c1ncc(COCCCCc2nnn[nH]2)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CNc1nc(Nc2cc(F)c(N3CCCCC3=O)cc2OC)ncc1C(F)(F)F +CCOC1(c2ccccc2)Sc2ccccc2-n2c1noc2=O +CCC(C(=O)NCCCN1CCC(c2cccc(NC(=O)C(C)C)c2)CC1)(c1ccccc1)c1ccccc1 +Nc1scc(CN2CCN(c3ccc(C(F)(F)F)cc3)CC2)c1C(=O)c1ccc(Cl)cc1 +CCCCCCCCCCCCNC(=O)Oc1cccc(-c2csnn2)c1 +CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)C=Cc1ccccc1 +CCN(CC)C(=O)CN(c1cc(Cl)ccc1N(C)C)S(=O)(=O)c1ccc(OC)c(OC)c1 +Cc1c(C(=O)N2CCc3ccccc3C2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1-c1ccccc1 +CC(C)(C)OC(=O)c1cc2c(cn1)[nH]c1ccc(F)cc12 +CCN(c1cc(-c2ccc(CNCCO)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCOCC1 +CN(C)CCOc1ccc(Nc2cc(-n3cnc4cccnc43)ncn2)nc1 +COc1ccc2ccc(OC)c(CCNC(=O)C3CC3)c2c1 +Cc1c(C)c2c(c(C)c1N)CC(C)(CSc1ccc(O)cc1)O2 +CC(c1ccccc1)N1CCN(c2c(Cl)cnc3[nH]c(-c4ccc(N(C)C)cc4)nc23)CC1 +CS(=O)(=O)Nc1ccc(-c2cncc3ccccc23)c(OC(F)(F)F)c1 +COc1cccc(C(C)NC(=O)c2ccc(-c3c(C)n[nH]c3C)cc2OC)c1 +CON=C(CCN1CCN(c2ccccn2)CC1)c1ccccc1C +CC(O)c1cnc(N2CCn3c(nc4ccc(S(C)(=O)=O)cc43)C2C(C)C)nc1C(F)(F)F +OCCCOc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +CCC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)CCC1O +C=CCN(C(=O)OCc1ccc([N+](=O)[O-])cc1)C1CCN(CCC(Cn2cncn2)c2ccccc2)CC1 +CC(C)NCC(O)COc1ccc(CCOCC2CCCC2)cc1 +NC(CC(CC=Cc1ccc([N+](=O)[O-])cc1)C(=O)O)C(=O)O +CCCCNC(=O)CC(O)C(CC(C)C)NC(=O)C(NC(=O)Cc1ccc2ccccc2c1)C(C)CC +C=CC(=O)Nc1ccc2c(c1)CC(=O)Nc1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn1-2 +Cc1nc2sccn2c(=O)c1CCN1CCN(C2CC(c3ccc(F)cc3)c3cc(Cl)ccc32)CC1 +COc1ccc(-c2cc3c(c(=O)o2)CC2(O)C(C)(CCC4(O)C(C)(C)C=CC(=O)C42C)O3)cc1 +Cc1nnc2n1-c1sc(C#CCn3c(=O)ccc4ccccc43)cc1C(c1ccccc1Cl)=NC2 +COc1ccc(OCC(C)(O)C(=O)N2CCc3c(C#N)cccc32)cc1 +CC(C(=O)NC1COC1)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 +CC(C)c1ccc(SCC(=O)N2CCOCC2C(=O)OCCCc2cccnc2)cc1 +CCCn1c(=O)c2c(nc3[nH]c(C)c(C)n32)n(Cc2ccccc2)c1=O +CC(=O)N(c1ccccc1)C1CC(C)N(C(=O)c2cccc(C)c2)c2ccccc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(N2CCC(F)(F)CC2)CC1 +O=C(NC1CCN(Cc2ccc(OC3CCNCC3)c(Br)c2)CC1)c1cc2ccc(-c3ccc(F)cc3)cc2s1 +CCC(=O)Nc1cc2c(NCc3ccccc3)ncnc2cc1OC +CC1C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C2C(OCc2ccccc2)C1 +COc1ccc2ncc(F)c(C(O)CCC3CCN(C4CC(c5ccc(F)s5)C4)CC3C(=O)O)c2c1 +COc1cccc(-c2cn(C3CCN(CC(N)=O)CC3)c3ncnc(N)c23)c1 +Cc1cc(N2CCN(c3ccnc4cc(Cl)ccc34)CC2)nc(Nc2ccccc2)n1 +Cc1noc(C)c1-c1cnc(N)c(-c2ccc(C(=O)NC(CO)c3ccccc3)c(F)c2)n1 +ON=C(CCN1CCN(c2ccccn2)CC1)c1ccc(Cl)cc1 +COc1ccc(S(=O)(=O)N2CCOC(Cn3ccnc3)C2)cc1 +CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCN(C2CCN(C(=O)OC3CCCC3)CC2)CC1 +O=S(=O)(NCC1CCCC1C(O)CCc1ccccc1)c1ccc(OC(F)(F)F)cc1 +CC(C)(Cc1ccc(O)cc1)NCC(O)c1ccc(O)c2c1OCC(=O)N2 +CSCCN1CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +COc1ccc(NC(=O)c2ccc(F)c(Nc3ncnc4cnc(N(C)CCN5CCCC5)nc34)c2)cc1C(F)(F)F +OC1CCN(CCOc2ccc(Oc3nc4ccccc4o3)cc2)CC1 +O=c1n(CCc2ccc3ccccc3n2)nc2cccc(-c3ccncc3)n12 +CCCCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)OCC +COc1ccc(NC(=O)Nc2nc3cn(CCc4ccccc4)cc3c3nc(-c4ccco4)nn23)cc1 +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(CSc2ccncc2)cc1 +Cc1cc(C(=O)NCc2cc(Cl)ccc2-n2cnnn2)cc(N(C2CCCC2)S(C)(=O)=O)c1 +N=C(N)c1ccc(-c2ncc(-c3ccc(C(=N)N)nc3)s2)nc1 +c1ccc2c(CCCCN3C4CCC3c3c([nH]c5ccccc35)C4)c[nH]c2c1 +O=C(c1cc(F)ccc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncon2)c1 +COc1ccccc1-c1ccc2[nH]c(C=CC3CCCCC3)nc2c1 +O=C(c1ncc[nH]1)N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +c1cc(-c2cc3c(cn2)[nH]c2ncc(-c4ccc(CN5CCCCC5)cc4)cc23)cnn1 +COCCc1nc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Nc2ccccc2)N2C1=NC1CCCC12 +COc1cc(C)c(Cc2nc(-c3ccc(-n4cnc(C)c4)c(OC)n3)n[nH]2)cc1C(C)C +COc1c(C)cc(Nc2nccc(-n3cc(C)c(CN4CC(O)C4)c3)n2)cc1C +CN(C)CCN1C(=O)c2cccc3c2c(cc2nc(-c4ccccc4)sc23)C1=O +CN1CCN(c2cccc(C(=O)Nc3n[nH]c4cc(OCCOCc5ccccc5)ccc34)c2)CC1 +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3cnn(-c4ccccc4)c3C(F)(F)F)c3ccccc32)CC1 +COc1ccccc1N1CCN(CCN(C(=O)C23CCC(CF)(CC2)CC3)c2ccccn2)CC1 +O=C(O)c1cc2c(Br)c(Oc3ccc(O)c(C(=O)c4ccc(F)cc4)c3)c(Br)cc2o1 +CC1C(O)C2(C)C(=O)C=CC3=CC(=O)C1(O)CC32C +COCCCN1CCN(C(=O)N2Cc3c(NC(=O)c4ccc(F)cc4F)n[nH]c3C2(C)C)C(C)C1 +CS(=N)(=O)CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 +CCc1cn(-c2nc(C(=O)O)cs2)c2cc(Cl)ccc12 +CC(C)CCN(C(=O)Nc1ccc(OC(F)(F)F)cc1)C1Cc2ccc(SC(C)(C)C(=O)O)cc2C1 +Cc1cnc(NC(=O)c2cc(Oc3cnc(C(=O)N(C)C)cn3)c3cn(C)nc3c2)cn1 +Cn1nc(-c2ccco2)cc1-c1ccc(C(=O)Nc2c(F)cncc2F)s1 +O=c1c2cc(F)ccc2[se]n1CCn1[se]c2ccc(F)cc2c1=O +NC(CC(=O)N1CCCC1CNC(=O)c1ccc(F)cc1)Cc1ccccc1F +NCC(c1ccc(Cl)cc1)c1ccc(-c2cn[nH]c2)cc1 +Nc1ncnc2c1ncn2C1OC(COP(=O)(O)CP(=O)(O)OP(O)(O)=S)C(O)C1O +COC1CCC2CCc3c(ccc[n+]3CCc3ccccc3)C2C1 +CN1CCN(c2nccc(NCCCNc3ccnc4cc(Cl)ccc34)n2)CC1 +COc1ccc(B(O)O)c(NC(=O)c2ccc(Oc3ccc(C(F)(F)F)cc3)nc2)c1 +COc1ccccc1Nc1ncccc1C(=O)NCC(O)CN1CCN(c2ccccc2OC(C)C)CC1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(NC(=O)C(N)C(C)(C)C)CC1 +CC(=O)N1CCN(C(=O)c2cc(CSc3cnc(NC(=O)c4ccc[nH]4)s3)cc(C)c2C)CC1 +Cc1cnc(C)c(N2CC3CCN(C(=O)c4c(F)cccc4-n4nccn4)CC32)n1 +CC1=CC(=O)N(Nc2nc(-c3cccs3)nc3sc(C(N)=O)c(C)c23)C1=O +NC(=O)c1ccc(N2CCN(c3ccccc3Cl)CC2)c2cncnc12 +CCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 +COc1cc(C(=O)c2nc(-c3ccc(N(C)C)cc3)c[nH]2)cc(OC)c1OC +COCCc1cc(OC2CC2)c(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C(C)C)n2)cc1C +COc1ccc(C2N(c3ccnc(NC(C)c4ccc(Oc5ccccc5)cc4)n3)C(=O)OC2(C)C)cc1 +O=C(C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1)N1CCC(O)C1 +NC(=O)C1(NC(=O)c2ccc(C3CC3)c(OCC3CC3)n2)CCOCC1 +Cn1c(=O)c2c(c(C#N)c(N3CCCC(N)C3)n2Cc2ccccc2)n(C)c1=O +NS(=O)(=O)NCCCCC(NC(=O)Cc1ccccc1)C(=O)Nc1nc(-c2ccccc2)cs1 +CCCC(CC(=O)O)n1ccc2cc(OCCc3ccc4c(n3)NCCC4)ccc21 +O=c1ccc2c(OCCCCOc3ccc4ccccc4c3)c3ccoc3cc2o1 +Cc1ncc(Cn2nc(I)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)s1 +N=C(Nc1ccc2c(c1)Cc1cc(NC(=N)c3ccccn3)ccc1-2)c1ccccn1 +C=CCOC(=O)CCCCCCCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +CC(O)CNc1nc(NCc2cccnc2)c2ncn(C(C)C)c2n1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(Cl)cc3)nn21 +Cc1cccc(-c2nsc(N3CCN(C(=O)Nc4ccccc4)CC3)n2)c1 +CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(C#Cc4cnc5[nH]c(C)cc5c4)c3)cc2C(F)(F)F)CC1 +COc1cc(-c2cc(C3CCCNC3)n3ncnc(N)c23)cc(F)c1CO +COCCn1nc(N)c2c(-c3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)cccc21 +CC(C)N1C(=O)C(C)(C)c2cc(-c3ccc(C#N)n3C)cc(F)c21 +O=C(OCC#CCSc1nnc(-c2cccc3ccccc23)o1)c1sc(Cl)c(Cl)c1Cl +CN(C)C1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NC3CCCC3)CC2)c(C)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(N=CN(C)C)cccc3nc2-1 +Cc1cc(OCCCNCC2CCCN(C)C2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 +FC(F)(F)Oc1ccc(OC2CC2)c(CNC2CCC3NC2(c2ccccc2)CC3c2nnn[nH]2)c1 +C=Cc1ccc(-c2cccc(CNc3nc(C#N)nc4c3ncn4CCCO)c2)cc1 +COc1ccc(COCCOc2ccc3c(NC(=O)c4ccc(N5CCN(C)CC5)cc4)n[nH]c3c2)cc1 +CN(CCCc1ccc(Cl)cc1Cl)c1nc(NCCc2ccc(O)cc2)nc(N2CCNCC2)n1 +Cn1nc(C(F)F)cc1C(=O)Nc1ccc(F)c(C2(C(F)F)N=C(N)OC3CC32)c1 +CN(C)C(=O)CCCCCCCCNC(=O)C(C)(Cc1ccccc1)NC(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C +N=C(N)NCCCCNc1ccnc2c1ccc1c(NCCCCNC(=N)N)ccnc12 +CCN(c1cccc2ccccc12)C1CCCc2nc(-c3c(C)cc(OC)cc3C)cc(OC)c21 +Cc1cc(F)ccc1S(=O)(=O)N1CCCC(Cn2ccnc2)C1 +N=C(N)c1ccc(-c2cccc(-c3ccc(C(=N)N)cn3)c2)nc1 +O=C(O)C(=O)CC(=O)c1cccn1Cc1ccc(F)cc1 +CC(C(=O)NCc1cc(Br)cc2nc(O)c(O)nc12)c1ccccc1 +O=C1C(=CC=Cc2ccc([N+](=O)[O-])cc2)c2ccccc2N1Cc1ccccc1 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+CCc1ncnc(-c2ccc(C(=O)N3CCN(C4CCOCC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1C +CC(C)n1c(=O)ccc2cnc(Nc3ccc(N4CCNCC4)cc3)nc21 +Nc1nc(NCCCCc2ccccc2)nc2c1ncn2C1OC(CO)C(O)C1O +O=S1(=O)N=C(NC2CCCCC2)OC2(COC2)C12CC2 +Brc1c(Br)c(Br)c2[nH]c(NC3CCNCC3)nc2c1Br +COc1c(Br)cc2nc(O)c(O)nc2c1[N+](=O)[O-] +COc1cc(OC)c(-c2c3cc(O)c(=O)cc-3oc3cc(O)c(O)cc23)cc1OC +CC(C)(C)c1[nH]nc2c1C(c1cccnc1OCCO)N(c1ccc(-c3ccco3)cc1)C2=O +CC(=O)Nc1ccccc1-c1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1 +COc1cccc2c1nc(N)n1nc(CN3CCN(c4cnn(C)c4)CC3C)nc21 +COC(=O)CSCCCCCC=C(NC(=O)C1CC1(C)C)C(=O)O +CCOc1ccccc1N1CCN(CCCNC(=NC#N)c2ccncc2)CC1 +O=[N+]([O-])c1ccc(-[n+]2c(-c3ccccc3)cc(-c3ccccc3)cc2-c2ccccc2)cc1 +CCC(CC)Nc1nc(C)nc(N(CC)c2ccc(C(C)C)cc2Br)n1 +CN1CCCCCCCCCCCC(=O)OCC2C(CC3CCC2N3C)c2ccc1cc2 +CS(=O)(=O)c1ccc(C(O)C(CO)NC(=O)C(Cl)Cl)cc1 +O=C(Nc1cccnc1)c1ccc(OC(F)F)c(OCC2CC2)c1 +[O-]c1ccccc1-[n+]1c(-c2ccccc2)cc(-c2ccccc2)cc1-c1ccccc1 +O=c1[nH]c(-c2cccc(=O)n2CC2CNCCOC2c2ccc(Cl)c(F)c2)no1 +CCCn1c(=O)[nH]c2[nH]c(-c3ccc(S(=O)(=O)NCCc4ccccc4)cc3)nc2c1=O +CCC(C)C(NC(=O)CC(C)C)C(=O)N1CCC(c2ccc(Cl)cc2)CC1 +O=C(c1ccccc1)N1CCC(CNCc2cccc(-n3cccn3)n2)CC1 +Cc1cc(S(=O)(=O)NC(=N)NNc2ccc(S(N)(=O)=O)cc2)c(SCc2ccccc2)cc1Cl +O=C1Nc2cc(Cl)c(Cl)cc2C1=C1Nc2ccccc2C1=NO +CCCCCCCCCCCCCCCCCC(=O)OCOC(=O)c1cn2c3c(c(N4CCN(C)CC4)c(F)cc3c1=O)OCC2C +Cc1cccc(-c2nc3ccccc3c(C(=O)NC(C)c3ccccc3)c2CN2CCC(N3CCCCC3)CC2)c1 +CC(C)(C)NC(=O)c1ccc2nc3[nH]c4ccccc4c3nc2c1 +CCNc1nc(Nc2cc(OC)c(C(=O)N3CCOCC3)cc2Cl)ncc1C(F)(F)F +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C)co1 +O=C(CN1CCCC1)Nc1ccc(C(c2ccc(F)cc2)(c2ccc(NC(=O)CN3CCCC3)cc2)C(F)(F)F)cc1 +Nc1ncc(-c2cc(N3CC(N4CCCC4=O)C3)nc(N3CCC(F)(F)C3)n2)cc1OC(F)F +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC(C)(Cc1ccccc1)C(=O)NCCCCCCCCO +N#Cc1cnc2ccc(NCc3cccnc3)cc2c1Nc1ccc(F)c(Cl)c1 +CCOc1ccc(Cc2cc(C3SC(CO)C(O)C(O)C3O)c(OC)cc2OC)cc1 +O=C1CCc2ccc(OCCCCNCCc3cn(Cc4ccccc4)c4ccccc34)cc2N1 +COc1ccc(C2(c3ccc(F)c(-c4cncnc4)c3)N=C(N)N(C)C2=O)cc1C +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(N3CCN(C4CC4)CC3)nc12 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+O=C(NC(Cc1ccc2oc(CCNc3ccccn3)cc2c1)C(=O)O)c1c(Cl)cccc1Cl +FC(F)(F)c1ccc(Nc2nc(-c3ccncc3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CN(CCc1ccc2cc(-c3ccc(C#N)cc3)ccc2c1)C(C)(C)C +CC(C)CCOc1ccc2c(c1)C1OCCCC1C(C1CCCCC1)N2 +O=C(O)CC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)CC1CCC1 +C=C1CCC2C(C)(C(=O)OC)CCCC2(C)C1CCC1=CCc2c(O)ccc(O)c2C1 +COc1cccc(Cn2c(CCCc3c[nH]c4ccccc34)nnc2C(Cc2c[nH]c3ccccc23)NC(=O)C(C)(C)N)c1 +CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3ccc(C(=O)O)s3)cc12 +Cc1ccc(NC(=S)OC(Cn2ccnc2)c2ccc(Cl)cc2Cl)cc1 +CC(C)(C)c1ccc(CN(Cc2cccs2)n2ccnc2)cc1 +O=C(C(Nc1ccccc1F)c1cc2ccccc2s1)N1CCCC1c1ccccn1 +CC(C)(Cc1ccc(F)cc1)NCC(=O)N1CCCC1C(=O)c1ncon1 +COC(=O)c1ccn2ncc(C=NN(C)S(=O)(=O)c3cc([N+](=O)[O-])ccc3C)c2c1 +COc1ccccc1Oc1ccccc1CN1CCC2(CC1)CCN(C(=O)c1ccc[nH]c1=O)CC2 +CNC(=O)C(Cc1ccc(NC(=N)N)cc1)NC(=O)C(CC(C)C)C(CCCc1ccccc1)C(=O)NO +O=C1C(=Cc2ccc(O)c(O)c2)C(c2ccc(O)c(O)c2)Oc2ccccc21 +O=c1[nH]c2c(-c3ccc(Cl)cc3)c[nH]c2c(=O)n1CCN1CCN(c2ccccc2Cl)CC1 +Cc1cc(-n2cccn2)c2cccc(OCc3c(Cl)cncc3Cl)c2n1 +CCCN1C(=O)C(C2=CC(=O)c3[nH]cc(CCN)c3C2=O)N(C)C1=O +CCCn1c(=O)c2nc(-c3ccc(OCc4nc(-c5ccc(C)cc5)no4)cc3)[nH]c2n(CCC)c1=O +O=C1C(=Cc2ccc(Cl)cc2)CN(C(=O)c2ccc(OCCN3CCCCC3)cc2)CC1=Cc1ccc(Cl)cc1 +COc1ccncc1-n1ccc2cnc(Nc3cc(OC)c(OC)c(OC)c3)nc21 +O=C(O)C(CCC(=O)N1c2ccccc2CC1C(=O)O)CCc1ccccc1 +Cc1nc(-c2ccccc2)c(C(=O)N2CCN(c3ccc(Cl)c(Cl)c3)CC2)o1 +COc1ccc(C2NC(C(=O)O)Cc3c2[nH]c2ccccc32)cc1CN1CCN(c2ccccc2F)CC1 +C=C(NC(c1ccc(Cl)c(F)c1)C1(F)CCNC1)c1ccc2cnc(Nc3ccnn3C)nc2c1 +Cc1ccc(C(N)=O)cc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12 +COc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNC4)CC3)ccc12 +CCCC(=O)N1CCN(c2nc(Cc3ccccc3)c3c(c2C#N)CC(C)(C)OC3)CC1 +COCc1ccc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)cc1 +COc1cc(CCNCCc2ccc(O)c3[nH]c(=O)ccc23)ccc1OCCCc1ccccc1 +Nc1noc2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(F)c(Cl)c5)CC4)cc3)c12 +COc1cc(C(=O)O)ccc1C=C1CCN(C(=O)C(C2CCCCC2)C2CCCCC2)CC1 +COc1c(Cl)cc(C2=C(c3ccc(S(N)(=O)=O)cc3)CCC2)cc1Cl +CC(=O)Nc1ncc(Cc2csc(CCO)c2C)c(N)n1 +COc1ccccc1N1CCN(CCN2C(=O)CC3(CCCCC3)C2=O)CC1 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+O=S(=O)(c1ccccc1-c1ccc(CNC2c3ccccc3CC2O)cc1)N1CCCCC1 +CSc1ncc(C2C(C(=O)OCCc3ccccc3)=C(C)NC(C)=C2C(=O)OCCc2ccccc2)n1Nc1ccccc1 +O=[N+]([O-])c1cc(F)ccc1S(=O)(=O)Nc1cccc2cccnc12 +Cc1cccc(C(=O)N2CC(C)OCC2Cc2cc(-c3ncccn3)ccc2F)c1-n1nccn1 +CCc1[nH]c(=O)c(N(C)C)c(Cc2cc(C)cc(C)c2)c1C +CC1(O)CC(c2nc(-c3ccc(SC4CCCCO4)cc3)c3c(N)nccn23)C1 +CCc1c(Cc2cc(C)cc(C)c2)nc(SCc2ccc([N+](=O)[O-])cc2)[nH]c1=O +Nc1ccc2c(c1)[nH]c1cc(C(F)(F)F)ccc12 +COC1CCC2(CC1)Cc1ccc(CC3CCCCC3)cc1C21N=C(N)N(C)O1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CC4c4ccccc4)ncc23)ccn1 +CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(CC(=O)NCc3c(C)cccc3C)c2)NC(=O)N1 +O=C1c2c(c(O)c3nccnc3c2O)C(=O)N1Cc1cc(Cl)cc(Cl)c1 +O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(Cl)cc3)cc2)cn1 +CC(C)(C)c1ccc(-c2cnc(N)cn2)c(F)c1O +N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCCCCOc3cc(C(F)(F)F)ccc3C(=O)N2)CC1 +CC(C)CC(C(=O)NC(Cc1ccc(OC(=O)c2ccccc2)cc1)C(=O)NC(C)(C)C)N(C)CC(C)C +CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(Cl)cn1)c1nccs1 +CCNC(=O)Nc1cn(-c2ncc(Br)cn2)c2cc(-c3ccn(C)c(=O)c3)cnc12 +O=C(C1CCCN(c2ccc3nc(-c4cc(C5CC5)ccn4)[nH]c3n2)C1)N1CCCC1 +COc1ccc2c(c1)C1(CC1c1ccc3c(C=Cc4cc(F)c(CN5CCOCC5)c(F)c4)n[nH]c3c1)C(=O)N2 +COC(=O)C1(C)CCCC2(C)c3cc(OC)ccc3CCC12 +CCCCCCS(=O)(=O)c1nc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)cc(C(=O)O)n1 +O=[N+]([O-])C=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)Nc1cccc(Oc2ccccc2)c1 +Cc1nn(C)c2ncc(C(=O)NO)c(N(C)S(=O)(=O)c3ccc(F)cc3)c12 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(C)s3)CC2)nc1 +Cc1cc(C2SCC(=O)N2CCCN(C)CCOc2ccc3c(c2)OCO3)cc(C(C)(C)C)c1O +CC(C)N1CCN(C(=O)c2ccc(C(CCN(C)C)Oc3ccc(C(F)(F)F)cc3)cc2)CC1 +CCOc1cc2c3c(c1)-c1c(ccc(O)c1O)CC3N(C)CC2 +C=CCn1c(=O)n(Cc2nc3ccccc3n2CCC(C)C)c2ccccc21 +O=c1[nH]c(N2CCC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CNc1nc(Nc2cc(OC)c(-c3cncn3C)cc2Cl)ncc1C(F)(F)F +O=C(C[n+]1cc(-c2ccc(F)cc2)n2c1CCC2)c1cccs1 +CCCN(CCC)C(=O)C(C)c1c(-c2ccc(Cl)cc2)[nH]c2ccccc12 +O=C(NCc1ccc(F)cc1)c1cn2c(c(O)c1=O)C(=O)N(CCOc1ccccc1)CC2 +O=C1NC(=O)c2c1c1ncccc1c1[nH]c3ccccc3c21 +O=C(NCc1ccc(-c2ccccc2)cc1)c1c(NCc2ccc(-c3ccccc3)cc2)[nH]c(=O)n(O)c1=O 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+Clc1ccc(-c2c(-c3ccc(Cl)cc3Cl)nc(CNC3CCCC3)n2C2CCC2)cc1 +Oc1ccc2c(c1)C13CCCCC1(O)C(C2)N(CC1CCC1)CC3 +OC1CC2CCCCC2CC1N1CCC(c2ccccc2Br)CC1 +Cc1cc(-c2nc3c(cnc4c(F)cccc43)[nH]2)on1 +CCCCCCCCCCCOC(=O)C(CCC(=O)NC(CCCC(N)C(=O)O)C(=O)O)NC(=N)N +O=S(=O)(c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cc1)N1CCCC1 +CC(C)CCc1nn(CCC(C)C)c(=O)c(C2=NS(=O)(=O)c3cc(OCC(N)=O)ccc3N2)c1O +CN(C)C(=O)n1nnc(-c2ccc(Cn3ccc4ccccc43)cc2)n1 +CCCCCN1C(=O)C(=NNC(=O)C(C)(C)C)c2ccc(OC)cc21 +Cc1cn(C2OC(COP(=O)(O)O)C(O)C2O)c(=O)[nH]c1=O +O=C1CCN(Cc2ccc3oc4cccc5c(=O)[nH]nc(c3c2)c45)CC1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(Nc3ccc(-c4ccccc4)cc3)CC2)CC1 +CC(C)(O)Cc1ccc2c(c1)c1cc(OCCCC(F)(F)F)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 +Cc1ccccc1-c1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 +CCCCN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1 +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCN1CCCCC1 +COc1ccc(C)cc1NC(=O)Nc1cccc(C(=O)c2cn(C3CCCC3)c3ncnc(N)c23)c1 +CCc1cccc2c1c(C(=O)c1ccc(Cn3c(C)nc4cnccc43)cc1)cn2C(=O)N(C)C +CC1=C2CCC3C(CCC4(C)C(O)CCC34)C2(C)CCC1=O +CC(C)CC(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)CNC(=O)NC(C)(C)C +Nc1nc(N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)c2nc(-c3ccc(F)cc3)sc2n1 +CCCS(=O)(=O)Oc1ccc(-n2c(-c3ccc(Cl)cc3Cl)nc(C(=O)NN3CCCCC3)c2C)cc1 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4cc(F)c(C#N)c(F)c4)CC3)c2c1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(C4CCCCC4)s3)c2)C(O)C(O)C1O +Cc1nc(N)nc2c1cc(-c1cnn(CC(C)(C)O)c1)c(=O)n2C1CCCC1 +Nc1ccccc1NC(=O)CCCCCNC(=O)c1ccccc1C(=O)c1ccccc1 +COC(=O)Nc1nc2ccc(S(=O)(=O)c3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2[nH]1 +C=S(N)(=O)C(C)(C)c1cc(N2CCOCC2C)nc(-n2c(NC)nc3ccc(F)cc32)n1 +Cc1noc(-c2cccc3c2-c2ccccc2C3(O)C(F)(F)F)n1 +Cc1ncn(-c2ccc(Cl)cc2C2=CC(=O)N(C3CCCC(C)C(=O)Nc4ccccc4-c4ccnc3c4)CC2)n1 +COc1ccc(CCNC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cc1 +COc1ccccc1N1CCN(Cc2c(C)nc3cc(C)nc(C)n23)CC1 +O=c1oc2ccccc2n1CC1CCN(Cc2ccc(-c3ccccc3)cc2)CC1 +COc1cc(OC)cc(-c2cncc(-c3ccc(N4CCNCC4)cc3)c2)c1 +Cc1ccc2c(c1)CN(CCc1ccc(C(C)C)cc1)C(=S)N2 +COc1ccc(-c2nc(CN3CCN(Cc4cccc(Cl)c4)CC3)c(C)o2)cc1 +CC(C)(C#N)c1cc(Cn2cncn2)cc(-c2ccc(OS(N)(=O)=O)cc2)c1 +CCCN(c1cc(C(=O)Nc2ccn(CC(=O)O)n2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC +NC1(c2ccc(-c3nc4ccc(-c5ccccn5)cn4c3-c3ccccc3)cc2)CCC1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3ccncc3)cc2)cc1)C(=O)O +S=c1[nH]c2ccc(OCCN3CCN(c4ccccc4)CC3)cc2[nH]1 +O=C(CCc1ccncc1)Nc1ccc(C(=O)c2ccccc2)cc1 +CCCN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +O=C(NCC(c1ccc(Cl)nc1)N1CCC(F)(F)CC1)C1COc2ncccc21 +CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(Cl)cccn12 +O=C(Nc1ccccc1N1CCCC1)c1ccc2ccccc2n1 +COc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Br)cc4)CC3)c2cc1OC +O=C(c1ccco1)N1CCN(c2cnn(CCCN3CCN(c4ccccc4Cl)CC3)c(=O)c2Cl)CC1 +CC(C)CC(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccc(Cl)cc2)cc1 +CC1CCCN1CCc1ccc(-c2ccc(S(=O)(=O)N3CCC(O)C3)cc2)cc1 +O=C(Nc1ccc(C(=O)N2CCc3c[nH]nc3-c3sccc32)cc1)c1ccc(F)cc1Cl +Cc1ccc(Oc2ccc(N(CC(NCc3cccnc3)C(=O)NO)S(C)(=O)=O)cc2)cc1 +CC(=O)N1CCCC(Nc2ncccc2-c2cnc3ccn(C)c3n2)C1 +CC(c1ccc(Cl)cc1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)CC1CCC(C(=O)O)CC1 +CCc1cccc(CC)c1-c1cc(OC)c2c(n1)CCCC2N(C)c1ccc(OC)c2ccccc12 +C#CCN(Cc1ccc2nc(CO)nc(O)c2c1)c1ccc(C(=O)NCc2cccc([N+](=O)[O-])c2)cc1 +CC(C)(C)OC(=O)NCc1cccc(CNC2CCN(CCc3ccccc3)CC2)c1 +O=C(NCc1nnc[nH]1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +CC1(C)Cc2nc(N3CCOc4ccc(Nc5ccc(N6CCNCC6)nn5)cc43)sc2C(=O)N1 +CC(C)c1cc(NC(=O)C2CCN(CC(=O)N3CCN(c4ccc(-c5ncccn5)cc4)CC3)C2)ccc1O +CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O +CC12CCC(O)C(C)(CO)C1CCc1cc(CO)c(O)cc12 +S=C(NCCCNCCCCNCCCNC(=S)NCC(c1ccccc1)c1ccccc1)NCC(c1ccccc1)c1ccccc1 +COc1cc(OCc2csc(C3(c4ccccc4F)CCOC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +[C-]#[N+]c1ccc(N2C(=O)C3(CCC3)N(c3ccc(CCCC(N)=O)cc3)C2=S)cc1C(F)(F)F +O=Cc1c[nH]c2c1ccc1c3ccc(Br)cc3[nH]c12 +CN(CCCOc1ccc(Oc2ccccc2)cc1)CCC(=O)O +CC(C)C1=C(Sc2ccccc2)C(COCCO)C(=O)NC1=O +CNC(=O)c1cc2c(Oc3ccc(C4(CO)CC4)cc3)cncc2s1 +CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(-c3nc(C(C)C)no3)cc2C#N)CC1 +[C-]#[N+]c1c(Oc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)nn(C)c1C(F)(F)F +CN(C)C(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C +COCC=Cc1c(Cl)c2c(Cl)cc(C(N)=O)nc2n1C1CCCNC1 +Cc1ccc(C(N)=O)cc1Nc1ncnc2c1cnn2-c1ccccc1 +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(CCc3ccncc3)CC2)cc1 +CC(C)OCCCNC(=O)CN1CCC(N(N)CC(=O)N2CSCC2C#N)CC1 +O=C(COc1ccc(Cl)cc1)Nc1nc2nn(CCCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +C=CCCC(=O)N1CC(C(C)OC(=O)CCCc2ccncc2)C1=O +Cc1ccc(NC(=O)c2cccc3c(N)nc(C)nc23)cn1 +COc1cc2c(Oc3ccc(NC(=O)c4nccc(-c5ccccc5)n4)cc3F)ccnc2cc1OCCCN1CCCC1 +N=C(Nc1ccc2c(c1)CCCN2C1CCNC1)c1cccs1 +Cc1nc2cc(OCC(O)CN3CCN(CC(=O)NC(C)c4ccc(F)cc4)CC3)ccc2s1 +Cc1cccc(C)c1-c1ccc(C(=O)NCCNC(=O)c2ccc(OC3C4CC5CC3CC(C(=O)O)(C5)C4)cc2)cc1 +COc1cc(-c2cc3ncccc3c(OCC3CNC(=O)C3)n2)cc(OC)c1OC +N#Cc1ccc(OC(F)(F)F)cc1N1CCC2(CCC(CC(=O)O)CC2)CC1 +CC1(C)CCCC(n2cnc(CC(CCCN)C(=O)O)c2)C1 +CC(C)N1CCCC(COc2ccnc3ccc(C#CCNC(=O)c4cccn(Cc5ccc(F)c(F)c5)c4=O)cc23)C1 +O=C(CCCCCN1CCN(c2cccc(C(F)(F)F)c2)CC1)c1ccccc1O +Cn1ncc2ncn(Cc3nc(CCc4ccc(Cl)cc4)no3)c(=O)c21 +Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC2(CCS(=O)(=O)CC2)c2ccc(N3CCOCC3)cc21 +NC1(c2ccc(-c3nc4cc(C5CC5)ccn4c3-c3ccccc3)cc2)CCC1 +CCc1coc2ccc(-c3cc(NC(C)c4cccc(O)c4)nc(C)n3)cc12 +CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2C2CC(CI)CCC21 +CNS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O +CCCCc1nc(SC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 +CC(C)n1nc(C(=O)NCC2CCN(CCNS(C)(=O)=O)CC2)c2ccccc21 +COc1cc2cc(NC(=O)CCCN(C)Cc3ccccc3)c(=O)oc2cc1OC +CC(C)(CCCC=C(c1ccccc1)c1cccnc1)C(=O)O +Cc1cc(OCC2Oc3ccccc3O2)ccc1C(=O)n1c(C)c(CC(=O)O)c2ccccc21 +COc1c(F)cccc1Oc1ccc(C(F)(F)F)cc1C(=O)Nc1ccc(C(=O)O)nc1 +COc1ccc2c(c1)C(=O)c1ccc(-c3nnc(C)o3)cc1S2(=O)=O +Cc1c(Cl)cccc1S(=O)(=O)NC(C)(C)CC(=O)NC1CCCCCC1 +CN1CCC(OC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1 +CN(Cc1ccccc1)C(=O)C(Cc1ccccc1F)NC(=O)C1CC(O)CN1C(=O)c1cn(C)c2ccccc12 +C=CCN1C2CCC1C(C(=O)OC)C(c1ccc(SCC)cc1)C2 +COc1ccc2c(c1)C(=O)C(c1ccc(Oc3ccccc3)cc1)=[N+]2[O-] +CC1CN(CCC(=O)NC2CCCCC2)C2Cc3ccc(O)cc3C1(C)C2 +O=C(CSc1nc2ccccc2c(=O)n1C1CC1)Nc1cc(C(F)(F)F)ccc1Cl 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+O=S(=O)(c1ccc(Nc2nc(SCc3ccccc3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1)C(F)(F)F +COC(=O)c1cccc(-c2cnc(C(=O)CCc3ccc(OC4CCN(C(=O)OC(C)(C)C)CC4)cc3)o2)n1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5Cl)CC4)cc3)cc2n(C)c1=O +CS(=O)(=O)Nc1ccc2ccc3ncc(-c4cnsc4)cc3c(=O)c2c1 +CCC(CC)CNC(=O)c1ccc2c(C)cn(Cc3ccc(C(=O)NS(=O)(=O)c4ccccc4Cl)cc3OC)c2c1 +CN(C)CCCOc1cnc(-c2cccc(Cn3nc(-c4cccc(F)c4)ccc3=O)c2)nc1 +CC1(O)CN(Cc2ccc(Nc3nccc(-c4cnc(N5CCC(F)C5)c(C#N)c4)n3)cn2)C1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(ncn2-c2ccccn2)C1 +COC(=O)c1sccc1NC(=O)Cc1cccc2cnccc12 +CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CNCC2CCCCC2)cc1 +CCC(CC)(c1ccc(OCC(=O)C(C)(C)C)c(C)c1)c1ccc(C(=O)NC(CC(=O)O)C(=O)O)n1C +CCCCc1nc2cc(C=CC(=O)NO)ccn2c1CN(CCC)CCCC +CCN1C(C(=O)NCc2cccc(C(F)(F)F)c2Cl)CCS1(=O)=O +O=C(NCCCN1CCOCC1)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COc1ccc(C(=O)NO)cc1NC(C)c1ccc(Cl)cc1 +COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cn1cc(C(C)=O)c2ccc(NC(=O)OC3CCCC3)cc21 +CN1C(=O)N(c2cncnc2)CC1C(=O)NCc1cccc(C(F)(F)F)c1Cl 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+c1ccc(-c2noc(C34CC5CC(CC(C5)C3)C4)n2)nc1 +O=C1NC2(CCCC2)C(=O)NC(Cc2ccccc2)C(=O)NCC=Cc2ccccc2OCCNC1Cc1cscn1 +CC1(C=Cc2cncs2)C(C(=O)O)N2C(=O)CC2S1(=O)=O +CC(c1nc2c(c(=O)[nH]1)C1CCCN1C(=S)N2c1ccccc1)N1CCOCC1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3[S+](C)[O-])c(=O)n(CC(N)c3ccccc3)c2=O)c1F +C=Cc1ccc(CN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 +Cc1ccc(C2OC(CO)C(O)C(O)C2O)cc1Cc1ccc(-c2ncccn2)s1 +CSCCc1c(-c2cccnc2)nn(-c2ccc(Cl)c(Cl)c2)c1OCCCC(=O)NC(Cc1ccccc1)C(N)=O +COc1cccc(Br)c1C(=O)NC(Cc1ccc(-c2cn(C)c(=O)n(C)c2=O)c(C)c1)C(=O)O +Cc1nc(-c2cn3c(n2)-c2cc(C(C)N4CCN(C(C)(C)C)CC4)ncc2OCC3)n(C(C)C)n1 +CC(C)c1ccccc1SC1=C(O)OC(c2ccccc2)(c2ccccc2)CC1=O +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N(C)C)nc2c1 +CCc1cc2c(c(OCC(F)(F)F)c(C(=O)NC3CCN(C(=O)CO)CC3)n2C)c(=O)n1CC(=O)c1ccccc1 +O=C(NCc1ccccn1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +COC(=O)c1[nH]c2ccc(Br)cc2c1Cc1cc(O)c(OC)c(OC)c1 +COc1cc(OCc2cccc(-c3ccc4nncn4c3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Cc1cnc(F)c(-c2nc(C(=O)Nc3cnn(C)c3N3CCCC(N)CC3)c(N)s2)c1 +COc1ccccc1-c1cc(NC(=O)c2cccc(NS(C)(=O)=O)c2)ncn1 +CCCCNC(=O)c1cc2ccc(O)cc2oc1=Nc1ccc(OC)cc1 +CCc1ccc(-c2nc3ccc(NCc4cccc(C(F)(F)F)c4)cc3n(CCNC(C)=O)c2=O)cc1 +COc1ccc(S(=O)(=O)n2ccc3c(CN4CCN(C)CC4)cccc32)cc1 +CCN1CCC(F)(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CC1 +CCCN(CCC)c1cc(C)nc2c(-c3ncc(N(CC)CC)cc3C)c(C)nn12 +NC1CC(N2CCn3c(nnc3C(F)(F)F)C2)COC1c1cc(F)ccc1F +NC(=O)c1nc(-c2ccccc2)cc2c1[nH]c1cc(C(=O)N3CCOCC3)ccc12 +O=C(c1ccccc1)c1cccc(C=c2[nH]c(=O)c(=Cc3ccccn3)[nH]c2=O)c1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)n1)c1ccc(F)cc1 +O=S(=O)(c1cccs1)c1nnn2c1nc(NCc1cccs1)c1sccc12 +O=C(c1cccc(F)c1-n1nccn1)N1CCOCC1Cc1cccc(-n2nccn2)c1 +NC(CO)(CCc1ccc(-c2cn(Cc3ccc(Cl)cc3)nn2)cc1)COP(=O)(O)O +Cc1cnc(-c2ccc(C3C(c4ccccc4)C3(Cl)C(=O)NO)cc2)nc1 +[C-]#[N+]c1scc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)cn4)CC3CO2)c1C +O=C(O)Cc1ccc(-n2nc(C3CCCC3)cc2NC(=O)Nc2nc(CCOCc3ccccc3)cs2)cc1 +CN1C2COCC1CC(OC(=O)c1cn(-c3cnn(C)c3)c3ccccc13)C2 +CCC(CC)Nc1cc(C)nc(Oc2c(C)cc(Br)cc2C)c1C +CC(C)(C)C(=O)Oc1ccc(C(=O)c2ccccc2)cc1CCC(=O)O +CN(C)c1ccc(-c2nnc(Nc3ncc(C(=O)NO)cn3)o2)cc1 +CC(C)S(=O)(=O)c1c(Cl)ccc(NC(=O)NC2CCCCC2)c1O +COc1cc(Nc2ncc(-c3nc(-c4ccccc4)cs3)c(NC3CC(CO)C(O)C3O)n2)ccn1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1c[nH]c2c(-c3ccccc3)cccc2c1=O +O=C(Nc1cc(Oc2ccncc2)cc(Oc2ccc(F)cc2)c1)N1CCC(O)(c2ccc(F)cc2)CC1 +CN(C)C1(CNCCC2CCCCCC2)COc2ccccc2OC1 +NC(CC(=O)N1CCNc2ccccc2C1)C1CCc2cc(F)c(F)cc21 +Cc1ccc(CN2C(=O)C(C(C#N)C(=O)O)c3ccccc32)cc1 +O=C1NC(=S)SC1=Cc1cc(Br)ccc1OCc1ccccc1Br +Cc1ccc(C=C(Oc2ccc(C=NNc3ccnc4cc(Cl)ccc34)cc2)C(=O)c2ccc(Cl)cc2)cc1 +COc1ccc(S(=O)(=O)N(CCn2cc(COCCOCCOCCOCCOCCF)nn2)C(C(=O)NO)C(C)C)cc1 +O=C(O)CCC(CC=Cc1cccnc1)CCCCNS(=O)(=O)c1ccc(Cl)cc1 +CCCCCn1c(C)c(C(=O)c2cccc3cccc(I)c23)c2ccccc21 +O=C(NC(Cc1ccc(OCCNc2nc3ccccc3[nH]2)cc1)C(=O)O)c1c(Cl)cccc1Cl +CC(C)Cc1ccc(OCC(=O)N(Cc2nc(-c3cccnc3)no2)C(C)C)cc1 +CCC(=O)N(Cc1ccccc1-c1ccccc1)C1CCNC1 +C=C(Br)C(=O)Nc1cccc(-c2cn3c(-c4ccc(OC)cc4)csc3n2)c1 +CC1(C)CC(=O)c2c(oc3c(Br)cc(NS(=O)(=O)c4ccccc4)cc23)C1 +c1cc2[nH]cc(CCCN3CCOCC3)c2cc1-n1cnnc1 +Cc1nccnc1C(C)N1CCc2c(ccc(COc3ccccc3-c3cccc(N4CCC5(C(=O)O)CC5C4)n3)c2C)C1 +CC(C)c1c(OCC(O)CN2CCCCC2)ccc2c1CCC1C(C)(C)CCCC21C +Cc1ccc2nc(C)c3nnc(-c4cc(OC5CCOC5)ccc4Cl)n3c2n1 +O=C(Nc1ccc(I)cc1)c1ccc(CN2CCOCC2)cc1 +CC(C)Oc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +COc1ccc2nc(C)c3c(C)nc(-c4cccn4C)n3c2n1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccncc2[nH]1)C1CCC1 +N#Cc1c(-c2cccs2)cc(-c2cc3c(ccc4ccccc43)oc2=O)[nH]c1=O +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)NCCN5CCCC5)c[nH]4)c3)cc2)c1 +COc1cc(C=C2C(=O)NC(=O)C2=Cc2ccccc2)cc(OC)c1OC +CC1(COc2ccc(Cl)cn2)CN(C(=O)N2CCN(S(C)(=O)=O)CC2)CC1c1ccc(Cl)cc1 +CN(C)CCOc1cc(N2CC3CNCC(C3)C2)cc(F)c1F +Cn1cc(F)cc(C2CCCN2c2ccn3ncc(C(=O)NC4CCC4)c3n2)c1=O +Fc1ccc(C23CCC4CCCCC4(OO2)C(OCc2ccccc2)O3)cc1 +COc1cc2c(cc1OCc1ccccn1)-c1n[nH]c(-c3ccc(-c4ccc(O)cc4)cc3)c1C2 +CC1CC1CNc1cc(C(=O)NC(Cc2ccccc2)C(N)CCC(F)(F)F)cc(N(C)S(C)(=O)=O)n1 +CC12CCC3C(CC4CC45CC(O)CCC35C)C1CC=C2c1cccnc1 +Brc1cnc(Nc2ccc3[nH]cnc3c2)nc1Nc1ccc2[nH]cnc2c1 +CC1(Cc2ccc(Br)cc2)C(=O)N(c2cc(Cl)cc(Cl)c2)c2ncc(S(=O)(=O)N3CCC(O)CC3)n21 +O=C1NCN(C2CCCCC2)c2c1cnc1[nH]ccc21 +COc1cc(OCc2cccc(-c3ccc(C(=O)OC(C)(C)C)nc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CNC(=O)C1OC(n2cnc3c(NC4CCCC4)nc(N)nc32)C(O)C1O +COc1ccc(Nc2ncc(C(C)N3CCN(S(C)(=O)=O)CC3)cc2-c2nc(C)nc(N)n2)cn1 +CCNC(=O)N1CCN(C)C(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2C)C1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4ccc(CO)cc4)nc31)C(O)C2O +COc1cn(C(CC(C)F)C(=O)Nc2ccc(C(=O)O)cc2)c(=O)cc1-c1cc(Cl)ccc1C#N +CC(C)Oc1ccc(COc2ccc3c(c2)c(Cl)c2n3CCC2CC(=O)O)cc1C#N +CCC(c1ccccc1)c1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc1-2 +O=C(O)COc1ccc(C(=O)c2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)cc1 +COc1ccc(CN(C)Cc2ccncc2)cc1-c1ccc(S(=O)(=O)NC2CCC2)s1 +COC(=O)C1=CN(Cc2ccc(OC)c(OC)c2)C=C(C(=O)OC)C1c1cccc(F)c1 +CCCN1CCC(CNCc2cn(-c3ccc(C(F)(F)F)cc3)nc2-c2ccc(C(F)(F)F)cc2)CC1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Cc2cccc(F)c2)C1 +O=C1NC(=O)c2c1c(-c1c(Cl)cccc1Cl)cc1c2c2cc(O)ccc2n1CCCC(=O)n1ccnc1 +CC(NS(=O)(=O)c1ccc2ccccc2c1)C(=O)N1CCCC1CNC(=O)C1CCCN(C(=N)N)C1 +CN(CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1)C(=O)c1ccc2nc(N3CCCC3)oc2c1 +Cn1ccnc1Sc1ccc(Nc2c(C#N)cnc3cc(C=CCCN4CCCCC4)ccc23)cc1Cl +CC(C)CN1C(=O)C(=Cc2ccc(N(C)C)cc2)SC1=Nc1ccccc1 +CCCCC(NC(=O)OC1CN(C(=O)Oc2ccccc2)CC1(C)C)C(=O)C(=O)NC(C)c1ccccc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cc(-c2ccc(Cl)cc2)n[nH]1 +COc1ccc(-c2nnc(-c3ccc4nc(-c5c(C)cc(CCC(=O)O)cc5C)[nH]c4c3)o2)cc1 +CC1CN(Cc2ccc(N(C)C)nc2)CC1c1nn2c(C3CCOCC3)ncc2c(=O)[nH]1 +COC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 +CCc1ncnc(-c2ccc(C(=O)N3CCC(N(C)C)C3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +CN1CCN(CCCn2cc(-c3cncc(-c4ccsc4)c3)c3ccccc32)CC1 +COc1n[nH]c2ncc(NC(=O)c3c(F)ccc(NS(=O)(=O)N4CCCC4)c3F)cc12 +CCCCNCC(=O)OC1C2(C(C)C)OC2C2OC23C2CCC4=C(COC4=O)C2CC2OC213 +CCCC(C)Nc1c2c(nn1Cc1ccc(-c3cccc(F)n3)cc1)N1C(=NC3CCCC31)N(C)C2=O +CN1C(=O)CC(c2ccccc2)C1C(O)c1cc(-c2ccccc2)cs1 +CCCCCCCCCCCn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1 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+O=C(O)C1(COc2ccc(-c3ccc(-c4ncc(C(F)(F)F)[nH]4)nc3)cn2)CCCC1 +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCN1CCC(c2ccccc2)CC1)C1CC1 +COc1ccc(Cl)cc1N1CCN(CCCN2C(=O)CC(C)(c3ccccc3)CC2=O)CC1 +CN(CC(=O)N1CCCCC1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCC1CCCO1 +Cc1c(F)cc(C(=O)NC2CC2)cc1-c1c(F)cn2c(-c3ccncc3Cl)nnc2c1F +[H]c1cc(-c2nnc(C34CCC(c5noc(C(C)(F)F)n5)(CC3)CC4)n2C)c(C(F)(F)F)cc1[H] +O=c1ccn(C2C=CC(OCP(=O)(O)OP(=O)(O)OP(=O)(O)O)O2)c(=O)[nH]1 +NC(=NO)N1CCC(CNC(=O)C2CCC3CN(S(=O)(=O)CCc4ccccc4)CC(=O)N32)CC1 +Cc1cccc(-c2nn(C(=S)Nc3cccc(C#N)c3)cc2-c2ccc3nc(C)nn3c2)n1 +CCc1cc2c(cc1N1CCN(CC3(O)CCNCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +Nc1nc(NCCNc2ncc(N3CCOCC3)c(-c3ccc(Cl)cc3Cl)n2)ccc1[N+](=O)[O-] +CC1(c2cc(NC(=O)c3ncc(Cl)cc3Cl)ccc2F)N=C(N)OCC1(F)F +O=C(Cc1ccccc1)NNC(=O)C(OCC=CBr)C(O)C(O)C(OCC=CBr)C(=O)NC1c2ccccc2CC1O +COC(=O)c1ccc2oc(C(=O)C(Cc3ccccc3)NC(=O)Cn3c(-c4cccc(F)c4)ncc(N)c3=O)nc2c1 +CNC(=O)c1nc(-c2ccc(Cl)c(S(=O)(=O)Nc3cccc(C)c3)c2)cnc1N +O=C(O)c1cccc(-c2ncccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 +Fc1ccc(CN2CCC(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +Cc1cc(N2CCN(C(=O)c3ccco3)CC2)n2ncc(-c3ccccc3)c2n1 +COC(=O)CC1(C(=O)Nc2ccc(-c3ccccc3C(=O)OC)cc2)CC(c2cccc(C(=N)N)c2)=NO1 +CCC(C)(C)Cc1c[nH]c(CCc2ccc(-c3ccccn3)cc2)n1 +CC(Sc1cc(-c2ccc(C(=O)N3CCN(C(C)C)CC3)cc2)cnc1N)c1c(Cl)ccc(F)c1Cl +COc1ccc(CC(O)CO)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)c1 +CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)cc2cn(C)nc12)C(=O)C1CC1 +O=C1N(c2ccc(OC(F)(F)F)cc2)CC2CC(NS(=O)(=O)c3cccnc3Cl)CN12 +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2NC2CCCCC2)N2C1=NC1CCCC12 +Cn1c(NC(=O)c2cccc(C#N)c2)nc2cc(C(=O)N3CCCCC3)cnc21 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCn3ccc4cccc(F)c43)c2)c1 +CC(C)(C)C1COCC(COC(=O)N2CCC(CO)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 +CC1CC1c1cc(NC(=O)Nc2ccc(Cl)cc2)n(Cc2ccccc2)n1 +COc1cc(Nc2nc3ccccc3nc2NS(=O)(=O)c2cn(C)cn2)cc(C(=O)N(C)C)c1 +CCCCNC(=O)CCC1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 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+NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1cccc(Cl)c1 +CCN(C(C)=O)c1ccc(Cl)c(COc2cccn3c(Br)c(C)nc23)c1Cl +CC(O)C(=O)NC(Cc1cccc(-c2nccs2)c1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +CC1CCCCN1c1ccc(N2CCN(S(=O)(=O)c3cccc(Cl)c3)CC2)nn1 +O=C(c1ccc(Oc2ncccc2C2CCCOC2)cc1)c1nc2ccccc2[nH]1 +N#Cc1cccc(-c2ccc3c(c2)CCN(CC(=O)Nc2cc(Cl)cc(Cl)c2)C32CCN(C3CCC3)CC2)c1 +Cc1ccc(NC(=O)N2CCc3nc(N4CCCC4)nc(OC(C)C)c3C2)cn1 +Cc1cc(NC(=O)C(C)(C)c2ccccc2)cc(S(=O)(=O)N2CCOCC2)c1C +CC(Cc1c[nH]c2c(OS(=O)(=O)c3cccnc3)cccc12)NCC(O)c1cccc(NS(=O)(=O)c2cccs2)c1 +CN(C)Cc1ccc(Nc2c(C#N)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)cc1 +CC(C)=CCCC(C)=CCCC(C)=CCN(C)C(=O)C(CP(=O)(O)O)C(=O)O +COc1ccc(Nc2c(-c3ccc(F)cc3)c(C)nn2-c2ccccc2C)c(C(=O)O)c1 +CN(C)c1ccc(C=Cc2sc3cc([N+](=O)[O-])ccc3[n+]2C)cc1 +CN1CC=C(c2c[nH]c3ccc(N4C(=O)c5ccccc5C4=O)cc23)CC1 +COc1cc2c(cc1Nc1nc(Nc3ccoc3C(N)=O)c3cc[nH]c3n1)N(C(=O)CN(C)C)CCC2 +O=C(Nc1ccc(Cl)cc1)N1C2CCC1CC(S(=O)(=O)c1ccccc1)C2 +O=C(NCCCc1cn2c3c(cccc13)CCC2)C1CCC1 +Cc1cc(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C(C)C)n2)c(OC2CC2)cc1C(=O)C(C)C +CCCN(Cc1sc(Nc2c(C)cc(Cl)cc2C)nc1C(F)(F)F)CC1CC1 +COc1cccc(CCCCCc2cccc(OC)[n+]2C)[n+]1C +O=C(NC12CC3CC(CC(C3)C1)C2)c1cn(CC2CCOCC2)c2ccccc12 +C=C(C)C(O)CCC(CO)C1CCC2(C)C3CCC(C(=C)C)C4(CCC(=O)O)CC34CCC12C +CC(=O)Oc1ccc(Cl)c(-c2cc(C)c3nc(Nc4cccc(OCCN5CCCC5)c4)nnc3c2)c1 +Cn1c(Nc2c(F)cccc2Cl)nc2cc(C(=O)Nc3cc(F)cc(C(F)(F)F)c3)c3c(c21)OCCO3 +N#Cc1c(-c2cccc(C=O)c2)[nH]c2nc(N)nc(N3CCCC3)c12 +N#Cc1ccc(Nc2nccc(NCc3cccc(F)c3)n2)cc1 +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(c2ncccn2)CC1 +CN1CCCN(c2ncc3ncnc(Nc4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4F)c3n2)CC1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cn5ncc6ccc(F)cc65)C4)cc23)ccn1 +O=C(NC1CCCC1Nc1cnc(C(F)(F)F)cn1)c1ccccc1-n1cccn1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NNC(C)C)[nH]c3ccc(Cl)cc23)c1 +CCNC(=O)Nc1cc(Nc2ccccc2)c(C(=O)Nc2ccccc2)cn1 +CC1OC(=O)C2(NCC3CC3)CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4C#N)cn3)C12 +CC(C)C(=O)Nc1cccc(C2CCN(CCCNC(=O)C(c3ccccc3)c3ccccc3)CC2)c1 +CC(CO)Nc1ncc2c(n1)CN(C(=O)NC1CNCC1c1ccc(C(F)(F)F)cc1)CC2 +Nc1nccn2c(C3CCC(CNC(=O)c4ccoc4)CC3)nc(-c3cc4ccccc4[nH]3)c12 +O=C(CCCc1ccccc1)N1CCC(Cc2c[nH]cn2)CC1 +CC(C)N1CCC(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)S1(=O)=O +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CN(C(=O)C(C)(C)O)C1)CC2 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3ccc(C(F)(F)F)cc3)cc2)C1CO +CCCCc1nc2ccc(N)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +c1ccc2sc(-c3cn[nH]c3NCCc3cnc[nH]3)nc2c1 +COc1cc(N)ccc1-c1ccc2c(-c3nc4c(N5CCN(C)CC5)cccc4[nH]3)n[nH]c2c1 +O=C(C(=O)N1CCN(C(=O)c2cc[nH]n2)CC1)c1c[nH]c2cccc(F)c12 +COC(C(=O)NC1CCc2ccccc2NC1=O)C(O)C(O)C(O)C=CC(C)(C)C +O=C(CCCCN1CCN(c2ccccc2)CC1)NC1c2ccccc2SCC2CCCCC21 +COc1ccccc1C(c1nnnn1Cc1ccc(F)cc1)N1CCN(C)CC1 +CCOc1cc(Cl)ccc1OC(c1ccccc1)C1CNCCO1 +Cc1ccccc1-c1cnnc(NCc2cc(-c3ccccc3)[nH]n2)n1 +COCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NCC2CCCCC2O)c1 +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCC(CCN2CCCC2)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(NC(=O)c2csc3c(N)ncnc23)c1F +COc1ccc(CN2CCC(NCCCCCCCCn3ccc4ccccc43)CC2)cc1 +O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3ccccc3F)CC2)nc1 +O=C(Nc1cccc2cccnc12)c1ccc(N2C(=O)C3C4CCC(CC4)C3C2=O)cc1 +Cn1cc(N2C(=O)c3nn(C4CC4)cc3C2c2ccc(Cl)cc2)cc(Cl)c1=O +Cc1nc2ccccc2n1Cc1ccc(CNC(=O)C(O)C(O)C(=O)N2CCCC2c2cccs2)s1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccc(C)cc2)c1 +COc1c(C(O)CN2CCN(C(=O)Cc3ccc(-n4cnnn4)nc3)CC2)ccc2c1COC2=O +O=c1n(Cc2nc3ccccc3n2CCCCF)c2cnccc2n1C1CC1 +CC(C)CC(C=O)NC(=O)C(NS(C)(=O)=O)C(C)C +O=C(Nc1cnn(S(=O)(=O)c2ccc(N3CCOCC3)cc2)c1)c1ccccn1 +CC(C)=CC(=O)Nc1sc(Nc2ccc3cc(CO)ccc3c2)nc1C(N)=O +CCOc1ccc2[nH]c3c([N+](=O)[O-])ccc4c3c(nn4CCNCCO)c2c1 +CC(C)N(Cc1cnc[nH]1)c1cccc(Oc2cccc(Cl)c2)c1 +CN1CCN(c2nc(Nc3ccccc3)c3cnn(C)c3n2)CC1 +CC1(C)OC2=C(CC1OC(=O)c1ccc(Br)cc1)C(=O)C(=O)c1ccccc12 +O=C(CNC(=O)c1ccc(Cl)cc1)OC(C(=O)Nc1ccc(Cl)cc1C(F)(F)F)c1ccccc1 +NC1CCC(Cn2nc(-c3ccccc3)c3cnc(NCc4ccccc4)nc32)CC1 +c1ccc(C2CCNC3(CCN(c4ncnc5[nH]cnc45)CC3)C2)cc1 +Cc1c(N)c(C)c2c(c1CC(C)C)OC(C)(C)C2 +CC(C)CNC1CCN(c2ccc(NC(=O)C(C)(C)c3ccccc3)cc2Cl)CC1 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+NC(=O)c1ccc(-c2cc(-c3ccc4c(c3)OCCO4)cnc2N)cc1 +CCCCc1nc2ccccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +Nc1ncnc2c1c(-c1cccc(O)c1)nn2Cc1cc2cccc(Cl)c2c(=O)n1C1CC1 +CC(C)(C)CC(=O)N1CCC(CNC(=O)c2cc(Cl)ccc2C2CCN(CCN3C(=O)COc4ccccc43)CC2)CC1 +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)c(F)c2)cn1C(C)C +COC(=O)C1C(c2ccc(C)cc2)CC2CCC1N2CC=CCF +CCNC(=O)Nc1nc2cc(-c3ccc4cnnn4c3)c(=O)n(C(C)C)c2s1 +CC(CCC(=O)NCCC(=O)Nc1nnc(S(N)(=O)=O)s1)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C +CC1=CCCC1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CC3(COC3)C2)c1O +CN(C)CCNC(=O)c1ccc([N+](=O)[O-])c2c(O)c3cccnc3nc12 +CCOc1ccc(Cc2cc(C3OC(SC)C(O)C(O)C3O)c(OC)cc2Cl)cc1 +CCCCc1nnc(SCc2ccc3ccccc3c2)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +COc1cc2nccc(Oc3ccc4c(C(=O)NCC(F)(F)F)cccc4c3)c2cc1OC +N#Cc1nccc(N2CC(S(=O)(=O)c3ccccc3C(F)(F)F)CC2C(=O)N2CCC(F)(F)C2)n1 +CCCN1CCC(=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)S1(=O)=O +NC(=O)C1CCC(c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)CC1 +COc1ccc(C2CC3CSC(N)=NC3(c3ccc(F)cc3F)CO2)cc1 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+CCN1C(=O)CCC1C(=O)NCc1ccc(F)c(C(F)(F)F)c1 +COc1cccc2c1c(=O)c1c(NCCN(C)C)ccc3c(CNCCN(C)C)nn2c31 +O=C(Nc1nc(-c2ccccc2)ns1)c1ccc(O)cc1 +COc1cc(CNC(=O)C2(Cc3ccccc3)OC(=O)N(C3CCc4ccccc43)C2=O)cc(OC)c1 +CCC(=O)Nc1cccc(C(=O)Nc2ccc(Nc3cc(-c4[nH]c(SC)nc4-c4ccc(F)cc4)ccn3)cc2)c1 +O=c1n(Cc2ccccc2)ccc2ncc(-c3cnc(Cl)c(NS(=O)(=O)c4ccc(F)cc4)c3)n12 +CCOC(O)=C1C(COCCN(C)C(=O)NC)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +O=S(=O)(Nc1c(F)c(F)c(NS(=O)(=O)c2ccc(F)cc2)c(F)c1F)c1ccc(F)cc1 +Cc1cc(C)c(-c2cc3cnc(N)nc3nc2NC(=O)NC(C)(C)C)c(C)c1 +Cc1ccc(NC(=O)c2ccc(C#N)cc2)cc1-n1c(C)nc2ccc(N3CCN(C)CC3)cc2c1=O +CC(C)(C)N1CCN(c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)CC1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1Br +CC(C)C(CN1CCC(c2ccccc2)CC1)NC(=O)C1Cc2ccc(O)cc2CN1 +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)NCc4ccccc4)cc3)cc2n(C)c1=O +Cc1ccc(C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)cc1N +Nc1nccn2c(-c3cccc(NC(=O)c4ccc(Br)cc4)c3)cnc12 +Cn1cc(-c2cc(NS(C)(=O)=O)cnc2Oc2ccccc2)c2cc[nH]c2c1=O +O=S(=O)(c1ccccc1)N(Cc1cccc(OC(F)(F)F)c1)c1sc2ccccc2c1Br +Fc1ccccc1Nc1nc2c(-c3nnc[nH]3)cccc2c2sccc12 +CN(CCc1ccccc1)C1C2C3CC4C2C(=O)C2C4C3C21 +Cc1ccc(CNC(=O)c2nc3ccc(-c4ccc(C5CCC(CC(=O)O)CC5)cc4)cn3n2)cc1 +CCCCNc1nc(NCCCC)nc(NCCc2ccc(S(N)(=O)=O)cc2)n1 +CC(C(=O)O)c1ccc(-c2cn3ccccc3n2)cc1 +CN(C)C(=O)N1C2CCC1CC(c1ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn13)C2 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCNC(=O)CNCC(=O)O)cc3)[nH]c2n(CCC)c1=O +N#Cc1ccc(CN(C(CCC(F)(F)F)C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)c(F)c1 +COc1ccc(-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c(N)c1 +CNC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1N2C +CCC(N)c1ccc(Cl)c(C(=O)c2ccc3c(c2)OCC(=O)N3)c1F +O=C(C=Cc1ccc(C=Cc2ccc3ccc(Cl)cc3n2)cc1)c1cc(-c2nn[nH]n2)ccc1O +CN(CC(CCN1CCC2(CC1)CC(=O)Nc1ccccc12)c1cccc(Cl)c1)S(=O)(=O)c1ccccc1 +O=C(OC12C3C4CC5C6C4C1C6C1(OCCCN12)C53)c1n[nH]c2ccccc12 +CCC1CC(=Cc2ccccc2Cl)C2=Nc3ccccc3CN21 +CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(NCCc3ccc(C(F)(F)F)cc3)c(Cl)c2)cc1 +Cc1csc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +Cc1ccc(NNC(=O)C(O)C(N)CSCC(C)C)cc1 +COc1cc(Br)cc(C2Nc3c(c(C)nn3C)C(=O)CS2)c1 +CCCc1nc(CC(NC(=O)c2cnc(C)cn2)C(=O)N2CCCC2C(N)=O)c[nH]1 +O=C(NO)c1ccc(NC2CCN(c3ccc(Cl)cc3)C2=O)cc1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cnn(-c2cccc(OC(F)(F)F)c2)n1 +CCCOC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1cccc(Br)c1 +CCCc1c(OCCCN(C)c2ccc(CC(=O)O)c(C)c2)ccc2c(C(F)(F)F)noc12 +O=C1NOCC1NCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CC(C)c1c(Cl)sc2nc(O)c(-c3cccc(Oc4ccccc4)c3)c(O)c12 +COc1cc2c(cc1OC)C(=O)C(CCC1CCN(Cc3ccccc3)CC1)C2 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4ccccc4Cl)c3)cc12 +CCc1cnc(Oc2ccc(NC(=O)c3ncccc3N)cc2Cl)nc1 +Cc1cc2c(cc1Cc1ccc(C(=O)NCC3CCCC(Nc4nccc(NCC5CCCO5)n4)C3)o1)C(C)(C)CCC2(C)C +Cc1ccc(NC(=O)C(C)C)cc1C1CCN(Cc2ccc(Oc3ccc(F)c(F)c3)cc2)CC1 +Nc1ncnc2nc(-c3ccc(N4CCC(O)CC4)nc3)cc(-c3cccc(Br)c3)c12 +FC(F)(F)c1ccc(Nc2ncnc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +c1ccc(Cn2cc(-c3c[nH]c4ncc(-c5ccncc5)nc34)cn2)cc1 +O=C(O)c1ccc2oc(-c3cccc(C=Cc4ccc5ccccc5n4)c3)cc(=O)c2c1 +COc1cc2cc(CO)c(CO)c(-c3cc(OC)c(OC)c(S(C)(=O)=O)c3)c2cc1OC +Cc1cn(Cc2ccc(Cl)cc2Cl)c2c(-c3cc(NS(=O)(=O)c4ccc(Cl)c(Cl)c4)no3)cc(F)cc12 +CCCCc1ncc(C=C(Cc2ccc(OC)cc2)C(=O)O)n1Cc1ccccc1Cl +O=C(CCc1noc2c1ccc1c(F)c(O)ccc12)NC1=C(C(=O)O)CCCC1 +CCOc1c(C=CC(=O)N2N=Cc3ccccc3C2C=C(C)C)cc(Cc2cnc(N)nc2N)cc1OC +O=C(O)CC(Cc1csc(CCCc2ccc3c(n2)NCCC3)n1)c1ccc(Cl)cc1 +O=C(Nc1ccc(C(=O)N2CCN(c3cccnc3)CC2)cc1)N1Cc2ccccc2C1 +Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(C5CCOCC5)cc4n3Cc3ccccn3)cn12 +CCc1cccc(NC(=O)N2CCc3nc(-c4ccc5ccccc5c4)nc(-c4ccccc4C)c3C2)c1 +CC(O)(c1ccnc(-c2cccc3cc(C(NS(=O)(=O)C4CC4)c4ccccc4Cl)sc23)c1)C(F)(F)F +O=[N+]([O-])c1cc(I)cc(C#Cc2ccccn2)c1 +Cc1ccc(C2COc3cc4[nH]c(=O)cc(C(F)(F)F)c4cc3N2CC(F)(F)F)cc1 +O=C(O)C(CC1CCC1)N1CC(CN2CCC(c3nnc4ccccn34)CC2)C(c2ccccc2)C1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1nccc2ccccc12 +CCCN1CCC(COc2nc3ccccc3c3cccc(F)c23)CC1 +CC1(O)C(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)OC1n1cc(-c2ncon2)c2c(N)ncnc21 +Cn1cnc(S(=O)(=O)NCc2ccc3c(c2)C(Cc2ccccc2)C(CN2CCC2)CC3)c1 +O=c1[nH]n(CC2COC(c3ccccc3)O2)c(=O)c2ccccc12 +CCCCCCCCC#CCCCCCCCC(=O)OCC1(CO)CC(=CCC(C)C)C(=O)O1 +CN1CC=C(c2cc(C(F)(F)F)ccc2-c2cccc3c2CCN(S(=O)(=O)Nc2ncns2)C3)CC1 +CC(C)c1oc2ccccc2c1Cc1ccc(C(=O)NC2CCOCC2C(=O)NO)cc1 +COc1cc(-c2nnc(SCC(=O)OC3CCCCC3)o2)cc(OC)c1OC +COc1ccc(CNC(=O)CCCCCCCCC(=O)NCc2ccc(OC)c(O)c2)cc1O +Clc1ccc2c(c1Cl)CN(CCCCN1CCc3ccc(Cl)c(Cl)c3C1)CC2 +NS(=O)(=O)c1cccc(-c2n[nH]c3ccc(OCc4ccccc4)cc23)c1 +O=c1oc2ccccc2n1CCCCCCCN1CCN(c2ccccc2)CC1 +CN1C(=O)CCc2cc(-c3cncc(CSc4nc5ccccc5o4)c3)ccc21 +Cc1cc(F)ccc1CN1CCN(c2ccccc2C)C(=O)C1=O +Nc1cnc(-c2ccc(-c3ccccc3Oc3cccc(C(F)(F)F)n3)cc2F)cn1 +CC(C)Oc1ccnc2ccc(C#CCNC(=O)c3cccn(Cc4ccc(F)c(F)c4)c3=O)cc12 +CC1CN(CCOC(C)(C)C)c2ccccc2C(C)N1C(=O)Nc1cccnc1 +COC(=O)Cc1cccc(NC(=O)C2(N(C)C)CCN(c3ncnc4[nH]c5c(c34)CC(F)(F)CC5)CC2)c1 +Cc1cc2n[nH]c(=O)n2c2cc(-c3cccc(CO)c3)ccc12 +CCN(CC)Cc1ccc(C=Cc2cc(-c3cc4c(=O)[nH]cnc4[nH]3)ccn2)cc1 +Cc1ccc(C(=O)Nc2cc(OCCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCSCC3)nc12 +Oc1ccccc1-c1nc(NC2CCCNCC2)c2ccccc2n1 +O=C(Nc1ccc(C(=O)N2CCCc3c(S(=O)(=O)O)[nH]c4cccc2c34)cc1Cl)c1ccccc1-c1ccccc1 +CC(C)(C)c1cc(N2CCN(CCCCNC(=O)c3cn4ccccc4n3)CC2)nc(C(C)(C)C)n1 +O=C(NCC(NCC1NCC(O)C1O)c1ccccc1)c1ccccc1Br +COc1cc(N2Cc3ccc(Sc4ccc(F)cc4)nc3C2=O)ccc1OCCN1CCCC1 +COc1ccc(-c2cccc3c2CCC2C3c3cc(O)c(Cl)cc3CCN2C)cc1 +COc1ccc(C)cc1-n1c(-c2ccc(Cl)cc2)cc2c1CC(C)(C)CC2=O +N=C(N)NCCCC(NC(=O)c1ccc2ccccc2n1)C(=O)NCc1ccc(C(F)(F)F)cc1 +COc1ccc(Nc2cc(Oc3cc(C)c(C)nc3-c3ccccn3)ccn2)cc1 +O=c1c2c(O)cc(O)cc2oc2oc3cc(O)ccc3c12 +CC1CN(c2ccc3[nH]c(-c4n[nH]c5ccc(OC(C)c6c(Cl)cncc6Cl)cc45)nc3c2)CC(C)N1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)c(F)c3)nc(CO)c12 +CC(C)C1=C(C(=O)N2CCOCC2)SC2=NC(c3ccc(Cl)cc3)C(c3ccc(Cl)cc3)N21 +CC(C)CC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1cn(C(C)(C)CN2CCCC2)cn1 +O=C(C1C=C2c3cccc4[nH]cc(c34)CC2N(C(=O)Nc2ccccc2)C1)N1CCOCC1 +CN(C)CCOc1ccc(Nc2nccc(-c3ccc(N4CCCC4)c(C#N)c3)n2)cn1 +O=C(NCCO)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +Cc1c(F)c(Oc2cccc(CC(=O)N(C)C)c2)nc(Oc2cccc(C(=N)N)c2)c1F +O=C(Nc1ccc(Cl)cc1)c1cccc2cc(Oc3ncnc4[nH]ccc34)ccc12 +CCN1CCN(C(=O)C2CCc3c(sc4ncnc(Nc5ccc6[nH]c(=O)sc6c5)c34)C2)CC1 +CC(C)C(C(=O)NO)N(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1 +COc1ccc(-c2c(C(=O)NC3CCN(CC4CC4)CC3)noc2-c2cc(Cl)c(O)cc2O)cc1 +CCCOCCn1c(=O)c(NCC(=O)N2CCOCC2)nc2ncc(-c3ccc(OC)nc3)cc21 +CCCc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 +CC(CC(Cc1ccc(-c2ccccc2)cc1)NC(=O)c1nnn[nH]1)C(=O)O +CCC(CC)(NC(=O)c1ccc(N(CC(F)(F)F)CC(F)(F)F)c(OCC2CC2)n1)C(=O)NC +CCc1nc2c(NC(C)=O)c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 +CCOP(=O)(c1ccc(-c2ccccc2)cc1)N1Cc2ccccc2CC1C(=O)NO +CN(C)C(=O)c1ccc(-c2ccnc3c2c(C=C2Oc4cccc(O)c4C2=O)cn3C)cc1 +O=C(NCC1CC23CCN(CC4CC4)C(Cc4ccc(O)cc42)C3(O)CO1)c1ccccc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2)n2c1COCC2)c1ccccc1 +O=C(Nc1ccc(O)c(O)c1)c1cc(O)c(O)cc1Br +CC1CCN(CCCCCCCCCCCC(=O)Nc2cc(CO)cc(Nc3ccnc4cc(Cl)ccc34)c2)CC1 +CCCS(=O)(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1 +Cc1cc(C#N)cc2nc(-c3ccc(NC(=O)CN4CCN(c5ccccc5Cl)CC4)cc3)oc12 +Cc1ccc(-c2nc3cc(N4CCCC4)ncc3[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +Cc1ccc2c(ccn2-c2cc(C(=O)N3Cc4ccccc4C3)c(O)cc2O)c1 +COc1ccc(-c2nc3c(NCCCNC(=O)c4cccs4)c(Br)cnc3[nH]2)cc1 +Cc1cccc(-c2oc(C3CC3)nc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 +O=C(NCCCCN1CCCC1)C1C(C(=O)NCc2ccc(Br)cc2F)C2C=CC1C21CC1 +CCN1C(=Cc2ccc3cc(OC)ccc3[n+]2CC)Sc2ccc(NC(C)=O)cc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(NCC2CC2)CC1 +COC(=O)c1ccc(C)c(NS(=O)(=O)c2ccc(OC)cc2)c1 +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(CCc3nccn3C)CC2)cc1 +COc1ccc(Nc2nc(-c3ccc(C)cc3)c(C(=O)Nc3sc4c(c3C(N)=O)CCCC4)s2)cc1 +O=S(=O)(c1cccc(F)c1)n1cc(C2=CCCNC2)c2ccccc21 +CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(C#N)c2)cn1 +CC(C)(C)OC(=O)N1CCC(N(C(=O)c2ccc(-c3ccc(C#N)cc3)cc2)C2CC2)CC1 +O=C(O)C(=Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)NC(=O)c1cccnc1Cl +NS(=O)(=O)c1ccc(NCC(=O)Nc2nc3ccc(S(N)(=O)=O)cc3s2)cc1 +Cc1cc(-c2n[nH]c(-c3ccnc(C#N)c3)n2)ccn1 +Cc1cnc2c(C(=O)NCC3CCN4CCCC34)cc(Cl)cn12 +COc1ccc2c3c1OC1CC(O)C=CC31CC[N+](CCCCCCCCN1C(=O)c3ccccc3C1=O)=C2 +O=c1[nH]c2ccccc2n(C2CC3C=CC(C2)N3C2C=CCCCCC2)c1=O +Cc1c(Nc2c(C#N)cncc2C=Cc2cccc(CN3CCCCC3)c2)ccc2[nH]ccc12 +O=C(c1nc2ccccc2[nH]1)N1CCC(Oc2ncccc2C2CCOCC2)C1 +CCc1nc(N)nc(N)c1-c1ccc(NC(C)c2ccccc2)c([N+](=O)[O-])c1 +NC(N)=NCCCC(N)C(=O)NCC1OC(OC2C(N)CC(N)C(O)C2O)C(N)C(O)C1O +O=C(Nc1ccc(Cl)cc1C(=O)O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 +O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccc(C(F)(F)F)cc12 +c1ccc(C23CCCC(OOC(C4CCCCC4)OO2)O3)cc1 +COc1ccccc1CN1CCC(N2CC(c3ccccc3)(c3ccccc3)NC2=O)CC1 +CC(=Cc1ccc(Oc2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cc1)C(=O)O +CC1C2Cc3ccc(O)cc3C1(C)CCN2CCN1CCCCCC1 +Cc1ccc(C2CC(NC(=O)Nc3cccc(Cl)c3)C(=O)N(CC(=O)NC(C)(C)C)c3cc(C)ccc32)cc1 +Cc1cccc2cc(Cn3nc(-c4cc(O)cc(F)c4)c4c(N)ncnc43)n(C3CC3)c(=O)c12 +CC(C)C(NC(=O)CC(C(=O)NCC(O)C(Cc1ccccc1)NC(=O)OCc1ccccc1)C(C)(C)C)C(C)C +Cc1ccccc1NC(=O)C(Cc1nc2ccc(C(=O)c3ccccc3)cc2nc1O)=NNC(=O)c1ccncc1 +Cc1nc2ccccc2n1-c1ccc(C(=O)N2CCC(N3CCCC3)C2)cc1 +CC(=O)NCC1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +N#Cc1ccccc1-n1c(-c2nonc2N)nc2ccccc21 +Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=O)c5cnn(-c6ccccc6)c5-c5ccsc5)cc4F)c3s2)c1 +C=C(C)C1CCC2(C(=O)N3CC(O)C3O)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC(C)(C)C(NC(=O)C(CCCc1ccccc1)CC(=O)NO)C(=O)NC(c1ccccc1)c1ccccc1 +COC1CN(C)CC1NC(=O)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1 +CC(N)C(=O)N1CCC(CC(=O)N2CCC(C3c4ncc(Br)cc4CCc4cc(Cl)cc(Br)c43)CC2)CC1 +O=C1NCc2c1c1c(c3c2c2ccccc2n3CCCO)Cc2ccccc2-1 +N=C(CCCCc1nnc(NC(=O)Cc2cccc(OCCCO)c2)s1)CCC(=N)NC(=O)Cc1ccccc1 +CC1NOC(C)C1c1ccc2c(c1)CN(C)CC2c1ccc2ccccc2c1 +N#Cc1c(-c2ccc(S(=O)(=O)NC(CF)CF)cn2)n(C2CCC2)c2cc(OC(F)F)ccc12 +Fc1cc(F)cc(CNc2cccc(-c3cc(NC4CCNCC4)ncc3Cl)n2)c1 +CCOC(=O)C=Cc1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(Br)cc1 +CCOc1cc(NC(=O)CCCCCCC(=O)Nc2cc(-c3ccccc3)ccc2N)cc2c1OCC([N+](=O)[O-])=C2 +O=c1c(O)c(-c2ccc(O)cc2)oc2cc(O)cc(O)c12 +CS(=O)(=O)c1ccc(C2SCC(=O)N2c2ccccc2)cc1 +Cn1cc(-c2cnc(N)c(C(=O)NCc3cc(F)ccc3F)c2)cn1 +Cc1cccc(NC(=O)Nc2ccc(-c3c(CCC(N)=O)sc4ncnc(N)c34)cc2)c1 +COc1cc2ncc(C(N)=O)c(Nc3cc(F)ccc3F)c2cc1OC +Cc1ccc(C(=O)Nc2cc(CN3CCCCC3)cc(C(F)(F)F)c2)cc1C#Cc1cnc2ccnn2c1 +CC1(CNc2nc(-c3cc(NC4CCC(N)CC4)ncc3Cl)ccc2F)CCOCC1 +Cc1cc(C)c(CNC(=O)c2cc(C#N)cc3c2CCN3C2CCCC2)c(=O)[nH]1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)O)cc3)c(Br)c2n(CCC)c1=O +[N-]=[N+]=Nc1cccc(COC(=O)NCc2ccc(C(=O)Nc3cc(-c4ccccc4)ccc3N)cc2)c1 +CCCN1C(=O)C(=O)c2cc(S(=O)(=O)N3CCCC3COC)cc(Br)c21 +O=C(CN1C2CCC1CC(c1cccc(O)c1)C2)C1CCCCC1 +CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(O)c(C(=O)O)c1 +CCn1c(Cc2c[nH]c3ccc(OC)cc23)n[nH]c1=S +O=C(c1cccc(CN2CCN(c3ccc4ccoc4c3)CC2)c1)N1CCCCC1 +Cc1cc(OCCN2CCOCC2)nn1-c1ccc(Cl)c(Cl)c1 +COc1cc(C=CC(=O)C=Cc2ccc(N(C)C)cc2)cc(OC)c1 +Cc1noc(C)c1Cn1cc(N2C(=O)NC(CC3CCCC3)C2=O)cn1 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4C[S+]([O-])Cc4ccccc4)C(C2)N(CC2CC2)CCC315 +Fc1ccccc1C(Cc1ccccc1OC(F)F)N1CCNCC1 +CC(=O)NC(C)CCc1ccc(Oc2ccc(OCC3CCC3)cn2)cc1 +COc1cc(F)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +COc1ccc(C=CCN(C)Cc2cccc3cc[nH]c23)c(F)c1 +NC(=O)Nc1cc(-c2ccnn2-c2ccccc2Cl)ccn1 +CC(Cn1ncc2c(Nc3cccc(O)c3)nc(SCCN3CCOCC3)nc21)c1ccccc1 +COc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)c(Cl)c1 +c1ccc(-c2nnc3c4ccccc4c(OCC4CCNCC4)nn23)cc1 +CCCOc1ccc2c(c1)C(=O)N(CCC(NC(CC(C)C)C(=O)NC(Cc1ccccc1)C(=O)NC)C(=O)O)C2=O +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C(=O)NC1CC1N +Cc1nc(NCC(F)(F)F)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CCc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc3c(c2)CCO3)ccc1OCCN1C(=O)CCC1=O +CCCCN(C)c1cc(C(C)(C)C)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +C=CCN1C(=O)C(C)(C)c2cc(-c3ccc(C#N)n3C)cc(F)c21 +CCN(CC)c1ccc(C(=O)N2CCCCc3ccccc32)c(Cl)c1 +CCOC(=O)c1ccc(OC(=O)c2ccc3c(c2)C(C)(C)CCN3C)cc1 +COc1ccc2c(c1)c(CCNC(C)=O)cn2Cc1ccccc1 +Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)cncc2F)nc1 +COc1cc2c(Nc3ccc(NC(=O)c4ccc(C)cc4)cc3)ncnc2cc1OCCCN1CCOCC1 +COc1ccc2nccc(NC(c3ccc(Cl)cc3)c3ccc(CN4CCCC4)cc3)c2c1 +O=C(O)c1[nH]cc(C(=O)NCc2ccc(F)cc2)c(=O)c1O +COc1cc2c(cc1OC)C(=O)N1C=C(c3cccc(C(=O)NCCCN(C)C)c3)CC1C=N2 +CC(C)(C)OC(=O)N1CCCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)C1 +Cc1nc2cc(C3CC4OC4(C)CCCC(C)C(O)C(C)C(=O)C(C)(C)C(O)CC(=O)O3)ccc2n1C +O=c1[nH]c(=O)n(COCCO)c(Sc2ccccc2)c1C=C(c1ccccc1)c1ccccc1 +COc1cc2ncnc(Nc3cnn(CC(=O)Nc4ccc(N(C)C)cc4)c3)c2cc1OC +Cc1nc(-c2cc3cc(N)cc(C#N)c3[nH]2)sc1C(=O)O +CN(C)C1CCN(C(=O)Cn2c(-c3ccc(Cl)cc3)c(C3CCCCC3)c3ccc(-c4noc(=O)[nH]4)cc32)CC1 +CCCCc1nn(COc2ccc(Cl)cc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCCCCNc1cccc(CNc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NC(C)C=CCCCc1ccccc1 +Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cocn1 +O=C1C=C(c2ccc[n+]([O-])c2)S(=O)(=O)c2ccccc21 +CN=C(NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +CC(=O)Nc1cc(-c2ccc3c(c2)OCO3)cc(-c2ccc3c(c2)OCO3)n1 +CC(C)CC(C=O)NC(=O)C(CO)NC(=O)OCc1ccccc1 +N=C(N)NCCCC(N)C(=O)NCCCCCCCNCCCCCNC(=O)C(CC(N)=O)NC(=O)Cc1ccc(O)cc1O +Cc1cccc(C2CCCN(c3ncnc4cc(N5CCOCC5)ccc34)C2)c1 +Cc1nc2ccc(Oc3ccc4c(c3)OCO4)nc2c(=O)n1CC1CCCN(C(C)C)C1 +Cc1ccc(S(=O)(=O)NC(Cc2cccc(C(=N)N)c2)C(=O)N2CCN(C(=O)OCc3ccccc3)CC2)cc1 +C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CC[N+](C)(C)[O-] +COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(Br)c(N)c2)c(OC)c1 +COc1cnc(Cl)c(Nc2ncnc3cc(OCCCN4CCOCC4)cc(OC(C)C)c23)c1 +COc1c(C2CCC2)ccc(-c2cnc3[nH]cnc3c2)c1F +O=C(c1nnc(-c2ccccn2)o1)C1CCc2cc(Oc3ccccc3)ccc2C1 +O=C(OCCCCCCCCCCCCCCCC[n+]1cccc2ccccc21)c1ccc(O)cc1O +O=C(NC1CCN(C(=O)CCc2cccnc2)CC1)C(c1ccc2ccccc2c1)C1CCCCC1 +COc1ccc(-c2nc(C(=O)N3CCCCC3)c(CN)o2)c2ccc(C(F)(F)F)nc12 +Cc1c(CCN2CCN(C(=O)Cc3cncc(-n4cnnn4)c3)CC2)ccc2c1COC2=O +Cc1ccc(C(=O)NCCCC[N+](C)(C)CCNC(=O)c2nc(Cl)c(N)nc2N)cc1 +CCN1CC(NC(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)nc4)ccc3n2)CC1=O +COC(=O)c1ccc(CNCC(C)C2CCC3=Cc4c(cc(C)oc4=O)OC3C2)cc1 +COc1ccc(CCNCC(O)COc2ccc(OCc3ncc[nH]3)cc2)cc1OC +c1ccc(Nc2ncnc3[nH]c(-c4ccccc4)nc23)cc1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(Cl)cc1-c1c[nH]nc1N +CCC(NC(=O)COc1ccccc1C)C(O)C(O)C1CCCN1C(=O)COc1ccccc1C +O=C(Nc1nc(-c2ccccc2)cn2cc(-c3ccccc3)nc12)c1cccs1 +Cc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccc(S(N)(=O)=O)cc2C)c(C)c1 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+COCCn1c2cnccc2c2cnc(Nc3ccc(N4CCNCC4)cn3)nc21 +NCCNc1cccc(-c2cc(NC3CCC(O)CC3)ncc2Cl)n1 +CC1CN(C(=O)c2ccccc2)CCN1C(=O)C(=O)c1ccc(-c2cscn2)cc1 +COc1cccc(CC2CCN(C(=O)c3nc4cc(O)c(O)cc4[nH]3)CC2)c1 +COc1cc(Nc2ncccc2C(=O)NCc2cn(Cc3cccc(Oc4ccccc4)c3)nn2)cc(OC)c1 +CCS(=O)(=O)c1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)c3[nH]ncc23)c1 +COc1ccc(-c2c(C)cccc2C)cc1COc1ccc(CCC(=O)O)cc1 +CN1C(=O)C(NC(=O)Nc2ccc(Cl)c(Cl)c2)N=C(c2ccccc2)c2ccccc21 +CCN(CCOC)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +CCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2n1)c1ccccc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(C4CCC4)c3F)C2)cc1 +Fc1ccc2onc(C3CCN(c4ccc(-n5ccnc5)nn4)CC3)c2c1 +CN(C1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1)C(CO)Cc1ccccc1 +NC(=O)c1ccc2c(n1)nc(NCc1ccccc1Cl)n2CC1COc2ccccc2O1 +C=CCN(C)CCCCCCOc1ccc2c(c1)c(C)nn2C +CC(C)N=C1SC(=Cc2ccc(CO)cc2)C(=O)N1c1ccccc1 +N#Cc1ccc2c(c1)CN(CCCCCCNC(=O)c1cc3ccccc3[nH]1)CC2 +COCCNC1CCC(Nc2cc(-c3cccc(NCC4CC(C)OC(C)C4)n3)c(Cl)cn2)CC1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1)CC2 +COc1cc2nc(NCCC3CCOCC3)nc(Nc3cnc(OC)c(C)c3)c2cc1OC +CN(C)CC(NC(=O)C1CC2CC2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)c1cccc(Cl)c1F +Cc1ccc(COc2ccc(NC(=O)NC(Cc3ccccc3)C(=O)NCCCN3CCOCC3)cc2)cc1 +c1cc(CN2CCCCC2)ccc1COc1ccc2c(c1)CCCC2 +Cc1ccc(S(=O)(=O)n2ccc(C(O)c3ccc(Cl)cc3Cl)c2)c(C)c1 +O=C(O)CCC(=O)N1CCc2cc(S(=O)(=O)N3CCN(c4cccc(Cl)c4)CC3)ccc21 +CC(=O)N1N=C(c2ccc(C)cc2)OC1c1ccc(Cl)c(Cl)c1 +Nc1c([S+]([O-])CCCCl)sc2nc(-c3cccs3)cc(-c3ccccc3)c12 +Cn1c(N2CCOC(c3ccc(NC4CCOC4)cc3)C2)nc(-c2ccncc2F)cc1=O +COc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)ccc1-c1cccc(-c2ccccc2)c1 +CN1CCCN(c2cncc(-c3cccc(C=CC(=O)O)c3)n2)CC1 +COc1ccc2cc(OC3CCN(c4ncnc5cc(OC)c(OC)cc45)C3)ccc2c1 +COc1cc(C(=O)Nc2ccc(C(=O)N3CCCCC3)c(O)c2)cc(OC)c1OC +CCCCCCC(=O)CCCCCCC=CCC(O)C(O)C(N)(CO)C(=O)O +O=C(NOC1CCCCO1)c1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 +CCc1ncnc(-c2ccc(C(=O)N3CCC(N(C)C)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +COC(=O)c1sccc1NC(=O)Cc1cccc2ncccc12 +O=C(CN1CCC(N2C(=O)OCc3cc(Cl)ccc32)CC1)Nc1ccc(Oc2ccccc2)cc1 +CC(=O)c1cccc(-c2nnnn2CCCN2CCC(Cc3ccccc3)CC2)c1 +Cc1ccsc1CNc1ncc(-c2ccc(CN(C)C)cc2)c2nncn12 +Cc1ncc(-c2nc(Nc3ccc(C(=O)N(C)C)cc3)ncc2F)n1C(C)C +CN1CCN(C(=O)c2ccc(-c3cc(Cl)c4c(c3)C3(CCCCC3)NC(=O)N4)cc2)CC1 +CN(C)CCNC(=O)c1cc(-c2ccccc2)sc1NC(N)=O +OCc1ccc(OCC(O)CNC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)cc1 +CC(C)CN(Cc1ccccc1)S(=O)(=O)c1ccc(-c2ccc(C(N)=O)cc2)cc1 +Cc1cc(Cl)ccc1NC(=O)c1cccc(Br)c1C(=O)NC(C)C +Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4CCC(S(=O)(=O)C(C)(C)C)C4)cc3)nn3cccc23)n[nH]1 +CCCN(CCCc1ccccc1OC)C1CCc2ccc3[nH]ccc3c2C1 +Cc1cc2c(s1)C13CC1CN(C(=O)OC(C)(C)C)C3=CC2=O +O=C(Cc1ccccc1)OC(Cc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCC2CC2)c1 +O=C(NC(=O)c1ccc(Cl)cc1Cl)Nc1cc(O)c(C(=O)O)cc1Cl +CC(C)NC(=N)c1ccc2oc(CCCc3cc4cc(C(=N)NC(C)C)ccc4o3)cc2c1 +CCCCN(C)c1nc(NC2CCN(C)CC2)c2cc(OC)c(OC)cc2n1 +CS(=O)(=O)C1CCN(c2cccc3c2cnn3-c2ccnc(NC3CCC(O)CC3)n2)CC1 +CN1C(=O)C(NC(=O)c2cccc(Cc3ccccc3)c2)COc2ccccc21 +Cc1cc(OCCN2CCC(n3cnc4cccnc43)CC2)nn1-c1ccc(Cl)c(Cl)c1 +CCCc1nc(C)n2c(O)nc(-c3cc(S(=O)(=O)N4CCN(C)CC4)ccc3OCC)nc12 +CN1CCN(c2ccc(Nc3ncc4ccc(-c5ccccc5N(C)S(C)(=O)=O)n4n3)cc2F)CC1 +CN(C)c1ccc(C=NNc2ccnc3cc(Cl)ccc23)cc1 +COc1cc(OC)c2c(c1)OC(=Cc1ccccc1O)C2=O +COc1ccccc1N1CCN(CCOc2ccc3nn[nH]c3c2)CC1 +O=C(COc1ccccc1)N1CCCCC1c1nc(-c2cccc(B(O)O)c2)no1 +COc1ccc(F)cc1-c1noc(-c2ccc(N3CCCCC3C)c(C(F)(F)F)c2)n1 +COc1ccc(-c2nnc(Nc3ccc(Oc4ccccc4)cc3)c3ccccc23)cc1 +N=C(CCc1ccc(Cc2c[nH]cn2)cc1)NCc1ccc(Cl)cc1 +Cc1cccc(C)c1Nc1ncc(-c2ccc(OCCN3CCOCC3)cc2)n2cncc12 +COc1ccc(C2(c3ccccc3)C(c3ccccc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1 +O=C(C1CCCN(c2ccc3nc(-c4ccnc(C5CC5)n4)[nH]c3n2)C1)N1CCOCC1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC(F)(F)F)CC3)c(OC)c2)c1C#Cc1ccc(N)nc1 +Cc1ccc(OCC(O)CN2CCCCC2)c(C(=O)CCc2ccccc2)c1 +O=C(O)c1ccc2c(c1)nc(Nc1ccc(Cl)c(C(F)(F)F)c1)c1ccncc12 +Cc1nc(NC(C)c2cccc(-c3cnc4c(c3)OCCN4C)c2)cc(-c2ccc3occ(C)c3c2)n1 +Cn1cc(-c2ccc(-c3cncc4ccc(C(=O)N5CCC5)nc34)cc2)cn1 +CCC1c2ccccc2-c2c([nH]c3ccccc23)C(=O)N1C +CC(C)(O)CNC(=O)c1cc(Cl)ncc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +COc1cc2c(cc1Cl)NC(NC(C)C)=NS2(=O)=O +O=C(C1CC1c1ccccc1)N1CCN(C2CCCCC2)CC1 +O=C(c1ccc(-c2cnc3ccc(NCC4CC4)nn23)cc1)N(Cc1cccc(Cl)c1)CC1CC(F)CN1 +CCCN1CCC2c3cccc(OS(=O)(=O)C(F)(F)F)c3CCC21 +CS(=O)(=O)c1cnc2nc(-c3ccc(-c4ccccc4F)cc3)[nH]c2c1 +OCC1C(O)C(O)C2CSC(=NCCCCCCCCCc3ccccc3)N12 +c1nc(N2CCC(COCCN3CCCC3)CC2)c2c(-c3ccc4c(c3)OCO4)csc2n1 +C=CC(=O)Nc1cccc(CNc2nc(Nc3cnn(C(C)(C)COC)c3)ncc2Cl)c1 +Cc1ccc(Oc2ccc(N(CC(Nc3cccc(F)c3)C(=O)NO)S(C)(=O)=O)cc2)cc1 +CCCS(=O)(=O)CCC12CCC(c3nnc(-c4ccccc4C(F)(F)F)n3C)(CC1)CC2 +NCc1cccc(-c2cc3c(cc2F)c(=O)c2c(=O)[nH]sc2n3C2CC2)c1 +Cc1ccc(NC(=O)N2CCC(CN3CCC(c4noc5cc(F)ccc45)CC3)CC2)cc1 +O=C(O)c1cc(-c2ccccc2)c2ccc(OCc3c(Cl)ccc(Cl)c3Cl)cc2c1 +CC(C)(CCCO)NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1 +O=C(O)C1=Cc2c(ccc(Cl)c2Sc2ccccc2)OC1C(F)(F)F +O=C(Nc1cccc(OC(F)(F)C(F)F)c1)c1ccc(N2CCCC2)c(C(F)(F)F)c1 +Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cc(Cl)nc(C(C)(C)C)c1 +CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3ccc(F)cc3)c2)CC1 +COCCn1cc(C#N)c2cc(-n3cc(C(=O)O)c(C)n3)ccc21 +Cc1ccc(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C)n2)nc1 +CCCC(CO)Nc1nc(C)nc2c1c(C)nn2-c1ccc(OC)cc1C +COc1ccc(CNC(=O)c2ccc(C)c(NC(C)=O)c2)c(C(F)(F)F)c1 +CCc1nc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)no1 +N#Cc1ccc(-c2cc3c(o2)C(=O)Nc2ccc(C4CCNCC4)cc2C3)cc1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CN(C(c2ccccc2)c2ccccc2)S(C)(=O)=O)CC1 +COCCOc1cc2nccc(Nc3ccc(Cl)cc3F)c2cc1OC +CC(C)OC(=O)C1=CN(C(=O)c2cccc(F)c2)CC(C)(C)c2cc(C#N)[nH]c21 +Cc1cc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)cn2CC(CO)O3)no1 +CC(c1ccc(S(=O)(=O)c2ccccc2)cc1)N1CCN(C)CC1 +C=C(C)CNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(NCCC)c3F)C2)cc1 +O=C1C=CC2(C=C1Cl)OCC(c1cccc(Br)c1)O2 +Cc1ccc(-c2ccc3c(c2)C=CS(=O)(=O)O3)cc1 +FC1(F)CCN(c2nnc(N3CCC(N4CCCCC4)CC3)s2)C1 +COc1cccc(CC(=O)n2c3cc(=O)n(Cc4cccnc4)c(C)c3c(=O)n2-c2ccccc2)c1 +O=C(NOCC(O)CO)c1ncncc1Nc1ccc(I)cc1F +Cn1nc(N2CCCC2)nc1CCc1nc2c(Br)cc(C(F)(F)F)cn2n1 +CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCN(Cc3ccncc3)C2=O)CC1 +Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(Cl)ccc3o2)cc1 +CCN(CC)C(=O)C1C=C2c3cccc4[nH]cc(c34)CC2NC1 +Cc1ccc(N2CCN(CCN3C(=O)CC4(CCCC4)CC3=O)CC2)c(C)c1 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+CCCc1n[nH]c2c1C(c1ccc(C)cc1)c1c(nc3c(c1N)CSCC3)O2 +O=C(CCCCCCc1ccccc1)c1ncc(-c2cscn2)o1 +Nc1nc(Nc2cccc(Br)c2)c2cc(CCc3ccccn3)[nH]c2n1 +NC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cc(F)cc(Cl)c1 +COC(C)(C)CCOC(=O)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O +CC1CCCN1C1CCC(c2ccc(NC(=O)c3ccccc3OC(F)(F)F)cc2)C1 +COc1ccc(-c2cc(-c3ccsc3)c(=O)n(C)c2-c2ccncc2)cc1 +CC(C)S(=O)(=O)NC1COCC1c1ccc(-c2ccc(F)nc2)cc1 +CSc1c(Cl)nc(N2CCN(C)CC2)nc1Nc1ccccc1 +CCCc1nc(C)c2c(NS(=O)(=O)C(F)(F)F)nc3ccc(OC)nc3n12 +O=S(=O)(Nc1ncns1)c1ccc2c(-c3ccc(C(F)(F)F)c(Cl)c3)nccc2c1 +CCCCc1ccnc(NC(=O)C2(CC(CCC)C(=O)O)CCCC2)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCc4cccnc4)c3)C2)cc1 +CC(=O)NCC(C=O)NC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +Cn1c(C(C)(C)C)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O +O=C(CCCCCC(NC(=O)c1ccc(Br)cc1)C(=O)NCc1ccncc1)NO +FCC1OC2(CCN(Cc3ccc(F)cc3)CC2)c2ccccc21 +CCc1ccc(Cn2cnc3c(N(C)C)nc(Cl)nc32)cc1 +NS(=O)(=O)c1ccc(C(=O)Cn2cnc3ccccc32)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NC3CCC(N(C)C)CC3)c2cn1)c1ccccc1 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3cc(Cl)ccc3[nH]2)o1 +O=C(c1nccc2[nH]cnc12)N1CCC(F)(F)C(Oc2ccc3ccccc3n2)C1 +CN1CC(Cc2ccccc2)(c2ccc(F)c(OCCN(C)S(=O)(=O)c3cn(C)cn3)c2)C1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(CS(C)(=O)=O)cccc4n3)c(C)c12 +CCCc1c(OCCCOc2ccc(C(=O)NC)c(OC)c2CC2CC2)ccc2c1OC(CCC(=O)O)CC2 +O=C(O)c1ccc(C2(NC(=O)C3CC4CC4N3Cc3ccc(C(F)(F)F)cc3)CC2)cc1 +Oc1ccc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1 +NC1CC(N2Cc3nn4cccnc4c3C2)CCC1c1cc(F)ccc1F +COc1ncc(C(F)(F)F)cc1Cn1cc(C(=O)NCCO)c2ncc(C)cc21 +COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3-c3ccccc3F)CC12C +CC(c1ccc(C(F)(F)F)cc1)N1CCC(NC(c2cccnc2)c2ccc(Cl)cc2F)CC1 +CCS(=O)(=O)N1CC(CC#N)(n2cc(-c3ncnc4[nH]ccc34)cn2)C1 +CCc1ccc(N2CC3CN(C(=O)Nc4ccc(OC(F)(F)F)cc4)CC3C2=O)cc1 +Cc1csc2cc(C(C)Nc3ncnc(N)c3C#N)c(Cc3cccc(CN(C)CC(C)C)c3)c(=O)n12 +Cc1cn(Cc2ccc(O)c(C(C)C)c2)c2c(Cl)cc(OCC(=O)O)cc12 +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3cccc(C(=O)NCCN4CCCC4)c3)nnc2c1 +CC(C)c1ccc(CNc2ccc3c(c2)ncn3-c2ccccc2)cc1 +O=C(NCCc1nnn[nH]1)C1CCCN(C(=O)CCC2CCNCC2)C1 +Cc1nc2nc(C(=O)Nc3ccn(C)n3)cn2c(-c2ccc(Cl)cc2Cl)c1CN +CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)N=c1sc(C(C)(C)C)cn1CC1CCCO1 +O=C(c1c(F)cccc1F)N1CCC(N(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Cc1c(Cc2ccccc2)nnc(N2CCN(c3cnc(C(C)(C)O)cn3)C(C)C2)c1CO +CC(C)N1CCC(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1 +COc1nc2ccc(Br)cc2cc1C(c1ccccc1)C(O)(CCN(C)C)c1cccc2ccccc12 +O=C(C=Cc1ccc(C(=C2C3CC4CC(C3)CC2C4)c2ccc(O)cc2)cc1)NCCO +Cc1cc(NC(=O)CC(=O)O)c(C)c(C)c1Oc1ccc(O)c(C(C)C)c1 +Cc1csc(-c2ccc(N)c(NC(=O)c3ccc(CNc4ccncc4)cc3)c2)c1 +CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC1CCCN2C(=S)N(Cc3ccccc3)C(=S)CC12 +c1cnc2nc3c(c(NCCCCCCCNc4c5c(nc6ncccc46)CCCC5)c2c1)CCCC3 +CCCC(NC(=O)C1C2CCCC2CN1C(=O)C(NC(=O)OC(C)C)C(C)(C)C)C(=O)C(=O)Nc1ccccc1 +CCOC(=O)c1c2c(n3cccc(F)c13)C(=O)c1ncccc1C2=O +O=C(CN1CCCCC1)c1ccc(OCCCN2CCCC2)cc1 +O=C1CCc2cc(C(c3ccncc3)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc3c2N1CC3 +O=C1C(CC(F)(F)F)=CC(O)(CSc2cccc[n+]2[O-])N1CCNc1ccnc2cc(Cl)ccc12 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(F)cc1-c1cc(F)ccc1F +CC(Nc1cc(F)cc(F)c1)c1cc(C(=O)NCCF)cc2c(=O)cc(N3CCOCC3)oc12 +O=c1c2scc(-c3ccccc3F)c2ncn1-c1ccc(Cl)cc1 +COc1ccccc1CNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 +Nc1cccc2cc(C(=O)NC3CN4CCC3CC4)sc12 +CC(C)CNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +O=C(c1cccc2ccccc12)c1cn(CCN2CCOCC2)c2ccc(O)cc12 +N#Cc1cnn(C(=O)N2CCN(Cc3ccc4ccccc4c3)CC2)c1 +C=CCC1CCCC(NC(=O)C(S)Cc2ccccc2)C(=O)N1CC(=O)O +CCCCCc1ccc(NC(=O)C2Cc3ccccc3CN2C(=O)c2cc(Oc3ccccc3)ccn2)cc1 +Oc1c(-c2ncc(C(F)(F)F)cc2Cl)cnc2c(F)ccc(F)c12 +CC1(C)CN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5O)c4n3)nn2)CCN1 +OCc1nc(Nc2ccc(C(F)(F)F)cc2)c2ccc(-c3ncccc3C(F)(F)F)cc2n1 +NC(=O)N1CC(S)C(NS(=O)(=O)c2ccc(Oc3ccccc3)cc2)C1 +Clc1ccc2c(Nc3ccc4oc(NCCN5CCCC5)nc4c3)ccnc2c1 +O=C1CC(=C(c2ccccc2)c2ccccc2)C(=O)N1CCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +CC(Cc1ccc(C#Cc2ccc(OCC3CC3)cc2)cc1)NC(=O)C1CC1 +CC(C)CC(C(=O)NC(Cc1ccccc1)C(N)=O)C(CSCC(=NO)c1ccccc1)C(=O)NO +COc1cc2c(cc1OC)CN(C(=O)CCC(=O)OCC#CCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1)CC2 +COc1ccc(COCc2cnc(Nc3cccc4[nH]ccc34)c(-c3nc(C)nc4[nH]cnc34)c2)cc1 +COc1cccc(N2CCC(Oc3ccc(N4N=C(C(F)(F)F)C(C)C4CC(=O)O)cc3)CC2)c1 +CC(Nc1ncc(F)c(N2C(=O)OCC2CF)n1)c1cn(-c2ccc(C(F)F)c(F)c2)cn1 +OCCCCc1nc(-c2ccc(F)cc2)c(-c2ccnc3[nH]c(-c4ccccc4)cc23)[nH]1 +COC(=O)C(C)(C)Cn1c(=O)[nH]c(=Nc2ccc(OC(C)C)nc2)n(Cc2ccc(Cl)cc2)c1=O +CCOC(=O)C1C(=O)C(=Cc2c[nH]c3ncccc23)OC1=Nc1ccc(CN(C)C)cc1C +COc1cccc(C(=O)c2sc(Nc3ccncc3)nc2N)c1 +CCCCCCc1ccc(C(=O)Nc2cccc3c(=O)cc(-c4nn[nH]n4)oc23)cc1 +CCOC(=O)N1CCC(c2ccccc2)(c2nccn2Cc2ccc(O)cc2)CC1 +CC(C)Nc1cc(-c2c[nH]c(C(=O)NC(CO)c3cccc(Cl)c3)c2)c(Cl)cn1 +ClC(Cn1ncc2c(NCc3ccccc3Br)ncnc21)c1ccc(Br)cc1 +CCNC(=O)c1ccccc1Nc1ncnc(Nc2ccc(CN)cc2)n1 +O=C(CCCCCNC(=O)c1ccc(-c2ccc(-c3cc(O)cc(O)c3)cc2)cc1)NO +Cc1cc(C)c(-c2[nH]c(CO)nc2C#N)cc1C(=O)N1CC(F)(c2ccc(C#N)cc2)C1 +CC(C)(C)C(=O)N1CCN(c2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2C#N)CC1 +Cn1nccc1-c1ccc(Cl)c(C(=O)NCC2(O)CCCCCC2)c1 +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCN1CCC2(C=Cc3ccccc32)CC1)C1CC1 +c1ccc(Nc2ncc3nnn(-c4ccccc4)c3n2)cc1 +CN(C)CCOc1ccc(-c2[nH]c3ncnc(NCC4SCCS4)c3c2-c2ccccc2)cc1 +CCNc1nc(C)c(-c2ccnc(Nc3ccc(CNC(C)=O)cc3)n2)s1 +CCOC(=O)CC(=O)NCC1OC(n2cc(Cc3ccc(C4CC4)cc3)c3c(Cl)cccc32)C(O)C(O)C1O +O=C(NCc1ccc(S(=O)(=O)N2CC3(CCOCC3)C2)cc1)N1Cc2ccncc2C1 +COc1cc(Oc2ccccc2F)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CC1=C(c2cn(C3CC(O)C(COP(=O)(O)O)O3)c(=O)[nH]c2=O)C(=O)c2ccccc2C1=O +Cc1cccc(F)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COc1cccc(C2=NNC(=O)C2=NNc2ccccc2Cl)c1 +Cc1ccc2c(c1)ncn2-c1ccc2[nH]cc(C3CCNCC3)c2c1 +Cc1c(C(=O)NCCN2CCN(C)CC2)cc(-c2ccc(-c3ccccc3)cc2)n1-c1ccc(S(N)(=O)=O)cc1 +Cc1cc(C)c2c(Nc3ccc(N4CCN(C)C(C)C4)cc3)c(C)c(C)nc2c1 +COc1cc2[nH]n(CC3(c4ccccc4)NC(=O)NC3=O)c(=O)c2cc1OC +COC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 +Nc1nc(CSc2ccccc2)nc2c1nnn2CC1CCCCO1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1Nc1ccc(N2CCC(N(C)C)C2)nc1 +CN(Cc1ccc(Cl)cc1)C(=O)C1(C)CCN1C(=O)c1csc2ccccc12 +O=C(NO)c1ccc2c(c1)CC(Nc1nccc(-c3cccnc3)n1)CO2 +NC(=O)C12CC3CC(C1)C(NC(=O)c1cccc(NS(=O)(=O)c4c(Cl)cc(Cl)cc4Cl)c1)C(C3)C2 +Cc1ccc(-n2c(C)nnc2SCC(=O)Nc2cccc(Cl)c2Cl)cc1 +CSc1cccc(N(CC(=O)O)C(=O)C(C)CSC(C)=O)c1 +COc1ccccc1C(Cc1coc2nc(N)nc(N)c12)C(C)C +O=C(NO)c1ccc(NC2CCN(c3cccc(Cl)c3)C2=O)cc1 +NS(=O)(=O)c1ccc(Nc2nc3ncnc(Nc4ccc(F)c(Cl)c4)c3s2)cc1 +Nc1c(N=Nc2ccc(-c3ccc(Cl)cc3)nc2)cc(S(=O)(=O)O[Na])c2ccccc12 +NS(=O)(=O)c1cc(S(N)(=O)=O)c(NSC(=S)N2CCOCC2)c(Cl)c1Cl +Fc1ccc(-n2c3c(c4cc(F)ccc42)CN(CCCCc2ccnc4ccccc24)CC3)cc1 +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(N)n[nH]c4c3)CC1)C2 +O=C(NC(CO)CO)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 +Cc1cc(=O)nc2nc(NC(=O)c3ccc(-c4ccc([N+](=O)[O-])cc4)o3)sn12 +CCN1CCN(C(=O)c2cn(C)c3cc(Nc4ncc(C(F)(F)F)c(NC)n4)c(Cl)cc23)CC1 +Nc1nc2c(cnn2CCc2cccc(-c3cccnc3)c2)c2nc(-c3ccco3)nn12 +Clc1ccc2nccc(N3CCC(CN4CCC(c5c[nH]c6ccccc56)CC4)CC3)c2c1 +CNC(=O)C(NC(=O)C(CCc1ccc(Cl)cc1)CP(=O)(O)Cc1ccc(Cc2ccccc2)cc1)C(C)(C)C +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(NS(=O)(=O)c4ccc(OC)cc4)cc3)ncc2F)c1 +COc1ccc(C2=NN(Cc3ccccc3)C(=O)C3CCCCC23)c2c1OC1(CCCC1)C2 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5oc(C#N)cc5c4)CC3)c2c1 +CCc1cc2c(C(F)(F)F)cc(=O)[nH]c2cc1NCC(F)(F)F +COc1cc2c(cc1OC)CN(C(=O)C1CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC1)CC2 +Cn1ncc2cc(-c3n[nH]c4ccnc(OC5CCOCC5)c34)ccc21 +Cc1[nH]c(-c2cc(N)ccc2Oc2ccccc2)c2c1C(=O)CCC2 +Cc1cc(C)c2c(c1)n(CC(=O)Nc1ccc3c(c1)CC1(C3)C(=O)NC(=O)N1C)c(=O)n2CC(N)=O +CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(C5=CC(=O)OC5)CCC43O)C2)C(O)C(O)C1O +COc1cccc(C#Cc2ccc3c(n2)CCN(C2CCCC2)C3=O)c1 +C#CCNc1ccnc2sc3c(=O)n(-c4ccc(OC)cc4)cnc3c12 +Cc1cc(C(=O)O)c(O)c(C(=O)C=Cc2cccc(C=Cc3ccc4ccccc4n3)c2)c1 +CCOC(=O)C1=C(C)NC(=Cc2ccn(-c3ccccc3C(F)(F)F)c2)C1=O +Nc1cc(Cn2c(C(=O)O)c(-c3ccc[nH]c3=O)c3cc(Cl)c(Cl)cc32)ccn1 +Nc1ccnc2c1C(=O)c1c(-c3ccccc3[N+](=O)[O-])ccnc1C2=O +Clc1ccc2c(NCCCN3CCN(CCCNCC4CC4)CC3)ccnc2c1 +O=C(O)c1ccn(S(=O)(=O)c2ccc3ccccc3c2)n1 +CC(C)(C)Cc1nc2cc(S(=O)(=O)Cc3ccccc3)ccc2n1CC1CC1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4cc5ccccc5s4)oc3C)ccc21 +CC1(c2ccc(OCCN3CCCCCC3)cc2)c2ccc(O)cc2CCN1c1ccccc1 +NC(COc1cncc(-c2cc3c(Cl)n[nH]c3cn2)c1)Cc1ccccc1 +O=C(Cn1c(=O)n(-c2nccs2)c2ccccc21)Nc1ccc2c(c1)CC1(C2)N=C(c2ccccc2)NC1=O +CC(=O)Nc1cn2cc(C=C3SC(=O)NC3=O)ccc2n1 +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4cocn4)o3)cc2Cl)CS1(=O)=O +CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cc2)cc1)C(=O)c1ccccc1 +Cc1ccc(C(=O)c2coc3c2C(=O)C(=O)c2ccccc2-3)cc1 +Cc1ccccc1-c1ccc2[nH]c(C=CC3CCCCC3)nc2c1 +CCOc1cc2c(-c3cccc(S(N)(=O)=O)c3)n[nH]c2cc1-c1cnn(C)c1 +COC(=O)c1cccc(-c2cnc(C(=O)C3CCc4cc(Oc5ccccc5)ccc4O3)o2)n1 +Cn1cc(C#N)c2ccc(NC(=O)Nc3ccccc3)cc21 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3cc(-c4cccc(Cl)c4)ccc3nc2-1 +CCCS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(c2cc(C)ccn2)CC1 +Cc1ccccc1C(=O)ON=C1CCS(=O)(=O)c2sccc21 +COCC(NC(=O)Nc1cc2[nH]nc(N3CC4CCC(C3)O4)c2cn1)c1ccccc1 +Cc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)cc1C +CC(Cc1ccc(F)c(F)c1)C(=O)NC1N=C(c2ccc3c(c2)OC(F)(F)O3)c2ccccc2N(C)C1=O +O=C(O)C1CCCN(CC[S+]([O-])C(c2ccccc2)c2ccccc2)C1 +COc1ccc(C=CC(=O)c2ccc(OC)c3c2OC(C)(C)C=C3)cc1N +CC(C)(C)c1ccc(CC(O)(CC(C)(C)c2ccccc2)C(=O)Nc2ccc3c(c2)COC3=O)cc1 +COc1ccnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4c(Cl)cnc(N)c34)c(OC)c2)c1 +NS(=O)(=O)c1ccc(N2C(=O)c3cccnc3C2=O)c(Cl)c1 +Cc1cc(N=c2[nH]c(=O)n(CCCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C +CC(OC1CN(C2=CC(=O)N(C)C2)CC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCCCCCC(C)(C)c1cc(NC(C)=O)c2c(c1)OC(C)(C)C1CCC(C)=CC21 +COc1ccc(C#N)c(S(=O)(=O)Nc2ccc(-c3nc(C4CC4)c4c(N)n[nH]c4n3)cc2)c1 +O=C(Nc1ccc(N2CCOCC2)cc1)c1cccnc1NCc1ccncc1 +Cc1cccc(C#Cc2ncn3c2COc2ccccc2-3)c1 +CC(C)COC(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +CN(C)S(=O)(=O)NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2 +Nc1cnc(-c2ccc(-c3ccccc3Sc3cnccn3)cc2F)cn1 +CNS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CN1CCOCC1)CCCC3)C(=O)N2 +CN1C(=N)NC(C)(c2sc(-c3ccnc(-c4cnco4)c3)cc2F)CS1(=O)=O +O=C(NC1CCC(c2cccc(F)c2F)CN(CCOC(F)(F)F)C1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1 +COc1cc(N(CC2CC2)c2ccc(F)c3ccccc23)cnc1C(=O)C1CC1C(=O)O +CCc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F +O=C(NCc1cccc(OCCOc2nc[nH]n2)c1)c1nc2scc(-c3cccc(Cl)c3)c2c(=O)[nH]1 +CCCCCNc1ncc(-c2ccccn2)c(NC2CCC(O)CC2)n1 +Cc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1C +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CC(O)CC(C)(C)O)CC(O)CC1O +COCc1nc2c(C(=O)Nc3ccccc3OC)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CNc1cc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)ccn1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(OC)cc1 +NC1CN(Cc2ccc(-c3csnn3)cc2)CC1C(=O)N1CCCC1 +N=C(N)c1ccc(COc2c(Cl)cc(C(=N)N)cc2Cl)cc1 +COc1cccc(C(=O)c2c(-c3ccccc3)[nH]c3ccccc3c2=O)c1 +Cc1ccc(CC(C)C(=O)N2CCN(c3ccc(C(F)(F)F)cc3C(N)CC(C)C)CC2)cc1C +COc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1NC1CCNCC1 +COc1cc(COc2ccc3c(c2)NCCN(C(C)C(=O)NO)S3(=O)=O)cc(OC)c1 +COc1ccc2nc(-c3noc(C4CCN(C(=O)CCC(F)(F)F)CC4)n3)sc2c1 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NC2CCOC2)cc1 +COCc1cccc(C=CC2C3CCCCC3CC3C(=O)OC(C)C32)n1 +CSCCC(C(=O)O)N(C)C(=O)c1ccc(CNc2cccnc2)cc1-c1ccccc1 +CN1CCN(c2cccc(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 +COc1cc(OC)c2nnc3c(C)nc(-c4ccccc4C)n3c2c1 +COc1ccc(C(=O)c2c[nH]c3c(OC)c(OC)c(OC)cc23)cc1O +CS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2-c2ccc3c(c2)OCCO3)cc1 +CCc1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)C(=O)O)cc1 +COc1cccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)c1 +CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2cccc(CNC(=O)CNC(=O)c3cccnc3)c2)n1 +CCOc1ccc2c(c1)NC(=O)Nc1cnc(C#N)c(n1)OCCC=CCO2 +CN(C)C(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccc(-c3ccccc3)cc21 +Cc1ncc(-c2ccc(C3(c4nnc5n4CCSC(C)(CO)C5)CC3)cc2)cn1 +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(OCCOC(F)F)c2cn1)c1ccccc1 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3cc(OC)c(OC)c(OC)c3)nn21 +CC(F)(F)c1n[nH]c2cc(NC(=O)NCc3ccc(F)cc3)ncc12 +CNC(=O)N1CC2C=C(c3cc4c(-c5cc(F)ccc5OC)ccnc4[nH]3)CC2C1 +COc1ccc(NC(=O)C(=O)Nc2ccc(OC)cc2C(=O)Nc2ccc(N3CCOCC3=O)cc2)cc1 +CCOC(=O)CCN1CCN(c2ccc3c(c2)C2CCN(C(=O)OCc4ccccc4)C3C2)CC1 +CC(CC(=O)Nc1cc(-c2ccnc3c(C(=O)c4cccs4)cnn23)ccc1F)C(F)(F)F +CCc1nc2cc(Cl)ccn2c1C(=O)NCc1ccc(N2CCC(c3ccc(F)cc3)CC2)cc1 +O=C1CC(N2CCN(c3ccc(O)cc3)CC2)C(=O)N1Cc1ccccc1 +CC1(O)C(O)C(COC(=O)NC2CCCC2)OC1n1cnc2c(NC3CCCC3)nc(Cl)nc21 +CCCCC(N)C(=O)Nc1ccc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OCc2ccccc2)cc1N +c1ccc(Cc2ccc(OCCn3cnc4cncnc43)cc2)cc1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(CO)c1ccc(Cl)c(F)c1 +CCCC(N)C(=O)N1c2ccccc2CC1c1ncc[nH]1 +O=C(CN1CCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)[nH]c23)c2oc3ccccc3c12 +Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc(Br)cc1 +CCNc1cnc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(F)cc4F)c3)cc2c1OC +CCc1c(O)ccc2nc3c(c(CC)c12)Cn1c-3cc2c(c1=O)COC(=O)C2(O)CC +Nc1ncc(-c2cccc(Cl)c2)nc1C(=O)NC1CCCC1 +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)C3CCCC3)ncc2c1 +C=CCc1c2c(cc(C(=O)OC)c1C(=O)OC)C1(C)CCCC(C)(C(=O)OC)C1CC2 +Cc1ccc(-c2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ncc(-c3ccccn3)cn2)cc1 +Cc1cccc(C)c1CN1CCc2ccc(CC(=O)O)cc21 +CCc1nc2c(c(C(N)=O)n1)CN(C(=O)CCc1ccc(OC(F)(F)F)cc1)CC2 +CN1CCC(c2ccnc(Nc3cc(-c4ccc(OC5CCOCC5)c(C#N)c4)ccn3)c2)CC1 +N#Cc1nc(N2CCOCC2)nc(N(Cc2ccc3c(c2)OCO3)C2CCCCC2)n1 +CCSc1ccccc1-c1ccc(-c2nnc(C3(c4ccc(Cl)cc4)CCC3)n2C)c(Cl)c1 +CC1CCC(NC(=O)c2cc3cc(-c4ccc(F)cc4)cnc3n(CCN3CCOCC3)c2=O)CC1 +O=C1CCc2ccc(NC(=O)NC3CCOc4c3cccc4C(F)(F)F)cc2N1 +CS(=O)(=O)c1ccc(Oc2cc(OC3CCOCC3)cc(C(=O)Nc3nccs3)c2)cc1 +Cc1ccc(NN=C2CCC(C)n3c2ncc(C(=O)O)c3=O)cc1 +O=C(CCN1CCCCC1)Nc1ccc(NC(=O)CCN2CCCCC2)c2c1C(=O)c1ccccc1C2=O +CCc1c(Sc2ccc(Cl)cc2Cl)[nH]c2nc(N)nc(N)c12 +CC(O)(c1ccc(S(=O)(=O)c2cccc(Cl)c2)cc1)C(F)(F)F +CC(=O)NC(C)c1ccc(OC2CCN(c3nccc(N4CC5(CCC5)C4)n3)C2)cc1 +C=CC1CN2CCC1CC2C(c1ccnc2ccccc12)S(=O)(=O)O +COc1nccc2[nH]nc(-c3ccnc(N4CC(C)OC(C)C4)c3)c12 +O=C(NNC(=O)C(OCC=CBr)C(O)C(O)C(OCC=CBr)C(=O)NC1c2ccccc2CC1O)c1ccccc1 +Cn1cc2c(nc(N(Cc3ccccc3)Cc3ccccc3)n3nc(-c4ccco4)nc23)n1 +O=P(O)(O)OC1C(O)C(O)C(OP(=O)(O)O)C(OP(=O)(O)O)C1O +COc1ccc(-c2c(O)ccc3nc(-c4cc(-c5cnn(C6CCNCC6)c5)cnc4N)oc23)cc1 +O=C1OCC(c2ccc(C(F)(F)F)cn2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +O=C(NCc1ccc(F)cc1)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N2CCCCC2)c1=O +CCc1nc2c(-c3ccc(OC)nc3C(F)(F)F)ccnc2n1C(CC)C1CC1 +CCCCC[S+]([O-])c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N +Cc1oc(-c2ccccc2)nc1CCCc1ccc(CC(C(=O)O)n2nccn2)cc1 +Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccn2)cc1Nc1ncnc2cnc(NCc3ccccc3)nc12 +C=CC1OC(n2cnc3c(NOC)nc(Cl)nc32)C(O)C1O +CCCC(C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(C#N)cc1 +Cc1ccc2sc(C(=O)Nc3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)cc2c1 +CCCCCCN1CNC(=O)C12CCN(C1CCCCC1c1ccccc1)CC2 +Cc1cc(-c2nc(C(=O)Nc3cnn(C)c3N3CCC(N)CC(F)(F)C3)c(N)s2)ccn1 +CC(CO)(CO)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3cc(OCCN5CCOCC5)ccc34)cc2)no1 +CC(C)(C)c1ccc(Nc2nc(N3CCCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CCn1nnc(C2OC(n3cnc4c(NCC5CC5)ncnc43)C(O)C2O)n1 +Cc1cccc(C(OC2CC3CCC(C2)N3C)c2ccccc2)c1 +CC(C)c1cccc2c1C(=O)N(COc1ccc(S(=O)(=O)N3CCOCC3)cc1)S2(=O)=O +COCCN1CCn2cc(C(=O)NCc3ccc(F)cc3)c(=O)c(O)c2C1=O +Nc1cccc(Cn2c(-c3ccc(Oc4ccccn4)cc3)ccc2-c2ccccc2Cl)n1 +CC(C)=CCn1c2c(ccc1=O)C(NCCc1ccc(F)c(F)c1)CCC2 +Cc1c2cc(-n3ccc(OCc4ccc(Cl)cc4)cc3=O)ccc2nn1C1CC1 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+O=C(c1n[nH]c2c1CN(CC1CC1)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 +Cc1c(O)cccc1C(=O)NC(Cc1ccccc1)C(O)C(=O)N1CSC(C)(C)C1C(=O)NC(C)(C)c1ccccc1 +c1cc2cc(-c3ccc(OC4CN5CCC4CC5)nn3)ccc2[nH]1 +CCc1nc(N)nc(N)c1-c1ccc(Cl)c(N=NN(CCOC(C)=O)Cc2ccc([N+](=O)[O-])cc2)c1 +O=CN1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +Clc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +CC(C)(Cc1nc(-c2ccc(O)cn2)no1)C(=O)NC1=C(C(=O)O)CCCC1 +CCCC1(CCC)CC(=O)C(C(c2ccccc2)C2CC2)=C(O)O1 +O=C(O)CCc1ccc(Nc2ncc3nnn(-c4ccccc4)c3n2)cc1 +CCN1CC(N(Cc2cc(F)ccc2Cl)c2ccc(C#N)c(Cl)c2)CC1=O +COc1nc(-c2ccccc2Cl)cc2nc(-c3csc(C(C)C)c3)[nH]c12 +Cn1cc(-c2cc(S(C)(=O)=O)ccc2OC2CCCCC2)c2cc[nH]c2c1=O +CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1CC(F)(F)F +Cc1cccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCCC6)ccn45)cccc32)n1 +O=C(CC(Nc1ccc([N+](=O)[O-])cc1)C1CCCCC1)c1ccc(Br)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2cnc(NC3CCCC3)nc2)cc1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2c(Cl)c(Cl)ccc2o1 +CCCOC(=O)c1c(-c2ccc(F)cc2)nc(CC)c(C(=O)SCC)c1CCC 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+O=C1c2ccccc2C(=O)N1CCCCCCCCCN1CCN(Cc2ccccc2)CC1 +O=C(Nc1ccc(N(CCCl)CCCl)cc1)Nc1c2ccccc2nc2ccccc12 +COc1cc(C(=O)N2CCNCC2)ccc1Nc1nc(Cc2c(Cl)cccc2Cl)n2ccnc2c1C(N)=O +O=C(O)C1CCC(O)(c2ccc(-c3ccccc3)cc2)C1 +Nc1nc2c(cnn2CCCc2ccc3c(c2)OCO3)c2nc(-c3ccco3)nn12 +Cc1ccc2nc(NC(=O)CNC(=O)c3nn(-c4ccc(F)cc4)c(=O)c4ccccc34)sc2c1 +C1=C(c2cnn3cc(-c4ccncc4)cnc23)CCC1 +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)C2=NOC(CCCCN=C(N)N)C2)C(=O)O)c(C)c1 +N#Cc1ccc2cc1Oc1ccc3c(c1)C(CC3)N1CCC(NCc3cncn3C2)C1=O +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3ccc(F)c(F)c3)ccc2[nH]1 +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2ccc(C(=O)OCC)cc2)C(C(=O)O)C1 +O=C1CC(C(=O)O)Oc2cc(COc3ccc(OCc4ccc5ccccc5n4)cc3)ccc21 +CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCC(=O)NC(Cc1ccccc1)C(=O)NN +CCCN1c2cc3c(cc2C2CCCCC21)c(C(F)(F)F)cc(=O)n3C +Cc1nsc(Nc2ncnc3ccc(Oc4c(F)cccc4S(C)(=O)=O)cc23)n1 +OC1(C(CN2CCNCC2)c2cc(Cl)sc2Cl)CCCCC1 +CN(C)c1ccc(C(F)(F)F)c(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(N)CC3)n2)n1 +Cn1nc(-c2ccc(F)cc2)c(-c2ccc3nc(NC(=O)c4ccnc(N5CCOCC5)c4)cn3n2)c1C1CCOCC1 +CC1(N)CCN(c2cccnc2NC(=O)c2nc(-c3nc(C#N)ccc3F)cnc2N)CC1 +COCCCOc1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)ccc1OC +Cc1nc(C)c(-c2ccc3cc(CCN4CCCC4C)ccc3n2)s1 +NC1CN(c2cc(-c3cccnc3)ncn2)CC1c1cc(F)c(F)cc1F +O=C(c1cccc(O)c1)c1ccc(Sc2cccc(O)c2)s1 +Cc1n[nH]c2c(NCC(C)C)cc(NS(=O)(=O)c3cccc(-c4ccccc4)c3)cc12 +CC1(C)C2CC3OB(C(CCCCN)NC(=O)C4CCCN4C(=O)c4ccc(Cc5ccccc5)cc4)OC3(C)C1C2 +c1cnc(Oc2ccc(Nc3nc4ccccc4s3)cc2)c(C2CCCOCC2)c1 +CC1(O)CCC(c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCC(=O)N(Cc3cccc(F)c3)c3ccccc32)n1 +OCC(Nc1ncnc2oc(-c3ccccc3)c(-c3ccoc3)c12)c1ccccc1 +CC(C)CN(c1ccc(C(O)(C#Cc2cccc(C#N)c2)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1 +Cc1nnc2n1-c1sc(C#CCn3c4c(c5cc(Cl)ccc53)CCCCC4)cc1C(c1ccccc1Cl)=NC2 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(C(F)(F)F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +O=C(CCCCNC(=O)c1nc(-c2nccs2)sc1C1CC1)NO +N#Cc1cncc(N2CC(S(=O)(=O)c3ccccc3Cl)CC2C(=O)O)n1 +CCNc1nc2cc(OC)c(Cl)cc2nc1-c1cccc(C(N)=O)c1 +CCCNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(F)cc3)CC2C)c(=O)c1=O 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+CC(C)(C)Nc1cccc2c1SC(OCCCO)C(=O)N2 +O=C(c1cccc(F)c1)N1CCn2nc(COc3cccc(F)c3)cc2C1 +CC1CN(S(=O)(=O)c2cccc3ccccc23)C(C)CN1C(=O)C(C)(O)C(F)(F)F +O=c1[nH]c2cc(CN3CCOCC3)ccc2c2c1CCCN2 +COC(=O)C1CC(c2ccc(Cl)c(Cl)c2)C2CC(=O)C1N2C +CN(CCc1nc2ccccc2n1CC(=O)Nc1ccc2c(c1)CCC2)C(=O)c1ccc2ccccc2c1 +COc1cccc(Cc2noc(-c3[nH]c4ccccc4c3CCN(C)C)n2)c1 +CN(CCO)c1cc(C(=O)O)nc2c(-c3ccc(F)c(CO)c3)nc(N3CCOCC3)nc12 +O=C(Nc1ccc2c(c1)CCN2)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CCC(=O)N1CCCC2(C)C(CCC3(C)C4CC=C(n5ccnc5)C4(C)CCC23)C1 +FC(F)(F)Oc1cccc(-n2nnc3ccc(NC4CCOCC4)nc32)c1 +OCc1cccc(Oc2cccc(-c3c(-c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1 +CCN(CC)CCCC(NC(=O)CCOc1cc(-c2cc(Cl)cc(Cl)c2)nn1-c1ccc2ccccc2c1)C(C)C +NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1Cc1ccccc1C(F)(F)F)Cc1cc(F)c(F)cc1F +CC(C(=O)O)N(C)C(=O)c1ccc(NC(=O)C(C)(O)C(F)(F)F)c(Cl)c1 +CC(=O)Nc1ccc(-n2c(-c3ccc(S(C)(=O)=O)cc3)nc3c2CCCC3)cc1 +CC(=O)c1ccc(-c2sc(NC(=O)NCCC(=O)NC(C)(C)C)nc2C)cc1 +O=C(NC1CC1)c1ccc(-c2cnc3c(NCc4cccs4)nccn23)cc1 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+CC(=NNC(=O)c1ccc(Cl)c(Br)c1)c1cc(Cl)ccc1O +COCCn1c(=O)c2c(nc(Cc3c(F)cccc3F)n2C)n(Cc2ccco2)c1=O +CC(C)OC(=O)Nc1cccc(-c2cccc3c(C(=O)c4cccs4)cnn23)c1 +c1ccc(-c2nn(-c3ccccc3)[n+](-c3ccccc3)n2)cc1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCC(F)(F)CC2)C1=O)c1ccccc1 +O=C(C1=C(c2ccc(CCCOc3c(F)ccc(F)c3Cl)cc2)CC2CNCC1N2)N(Cc1cccc(Cl)c1Cl)C1CC1 +Cc1nc(NC(C)c2cccc(OCC(C)(C)O)c2)cc(-c2ccc3occ(C)c3c2)n1 +CCCCCCC(=O)c1c2c(nc3ccc(OC)cc13)-c1cc3c(c(=O)n1C2)COC(=O)CC3(O)CC +c1ccc(-c2ccc(Oc3ccc(OCC4CCCCN4)cc3)cc2)cc1 +CC1(C2CCCCC2)NC(c2nc(-c3ccccc3)c[nH]2)Cc2c1[nH]c1ccccc21 +C=Cc1ccc(CN2CCC(NC(=O)CNC(=O)c3cc(C(F)(F)F)ccc3N)C2)cc1 +CN(C)Cc1cc(NS(C)(=O)=O)ccc1Oc1ccc(C(F)(F)F)cc1 +CCC1CN(C(=O)C2(C#N)CCC2)CC1Nc1c(C(N)=O)cnn2cc(-c3ccnc(Cl)c3)cc12 +COc1ccc(Cl)cc1Cc1c[nH]c2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc12 +CC(O)C(NS(=O)(=O)Cc1ccccc1)C(=O)NC(CCC(N)=O)C(=O)NCc1ccc(C(=N)N)cc1 +O=C(NCc1cccc(OCCOc2nc[nH]n2)c1)c1nc2scc(-c3ccccc3)c2c(=O)[nH]1 +CS(=O)(=O)N1CCCC1c1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cc1 +Cc1ccc(-c2c(CN)c(CC(C)C)nc(C)c2C(=O)OCc2ccc(C(=O)O)cc2)cc1 +CC(C)c1nc(Nc2cc(C(=O)O)nn2C)nc(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +Fc1ccc(-c2ncn(CCCNCc3ccccc3)c2-c2ccncc2)cc1 +COc1ccc(NC(=O)Nc2ccc(-c3ccc(C(=O)NC(C(=O)O)C(C)C)cc3)nc2)cc1 +O=c1oc(N2CCOCC2)cc2c(-c3cccc(-c4ccccc4)c3)cccc12 +CCN(CC)CCn1[nH]c2c3cc(C)ccc3nc3c([N+](=O)[O-])ccc1c32 +COC(=O)c1c(O)cc(O)c(Cl)c1CCc1nccn1Cc1ccc(C)cc1 +CC1CN(c2ccc(C#Cc3ccccc3)cn2)C(=O)OC1(C)C +COc1ccc(-n2c(C)nnc2SCC(=O)Nc2ccc(C)cc2Cl)c2ccccc12 +O=C(NCc1cc(Cl)ccc1-n1cnnn1)C1CC2CC2N1C(=O)C(O)c1cccc(F)c1 +CC1(c2cccc3ccccc23)NC(=O)N(CCCc2c[nH]cn2)C1=O +COc1cccc(CCC2CN(Cc3c[nH]c4cc(F)ccc34)CCC2(F)F)c1 +O=c1[nH]nc(-c2ccc(F)c(Br)c2)c2c1CCCC2 +O=C(c1cn(CCN2CCOCC2)c2ccccc12)C1CCCCC1 +CN(C)C(=O)C1CCC(Oc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)n2)CC1 +C#Cc1ccc2[nH]c(C(=O)N3CC4CC45C3=CC(=O)c3ccccc35)cc2c1 +CCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OCCN1CCOC1=O)S(=O)(=O)c1ccc(OC)cc1 +Cn1nc(-c2ccc(C(=O)NC(C)(C)CO)cc2)sc1=NC1CCCC(O)C1 +CCCn1c(=O)c2c(nc3[nH]c(C(C)C)cn32)n(Cc2ccccc2)c1=O +CC1(C)CN(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c21 +Cc1c(C)c(CNc2ccccc2)c(C)c(C)c1CNc1ccccc1 +COc1ccc(CN2C(=O)CN(C(=O)c3cc4ccccc4o3)CC2Cc2ccccc2)cc1 +COCCNC1CCN(C(=O)N(C)C(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(c2ccc(F)cc2C)C1 +O=C(OC1CCCCC1)c1cnc(Oc2ccc3c(c2)B(O)OC3)cn1 +COC(=O)C(C)(C)C(c1ccc(Nc2ccc(Br)nc2)cc1)n1ccnc1 +O=C1C(Cl)=C(Nc2ccc(CCO)cc2)C(=O)c2cnccc21 +CCCCc1nn2ncccc2c1-c1ccnc(Nc2ccc(N3CCN(C)CC3)cc2)n1 +CCc1c(Sc2ccccc2)n(COCc2cccs2)c(=O)[nH]c1=O +Nc1nc2cc(-c3ccc(CCCc4ccccc4)cc3)ccc2c(=O)n1CC1CCC(c2ccccc2)O1 +CN(C)CCCCNC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +COC(=O)C1(c2cccc(OCc3cccc(OC)c3)c2)CC1C(=O)NO +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)OC1CCCc2ccccc21 +O=C(Nc1ccc(O)c(Cl)c1)C1CCN(CC(=O)N2CCN(c3cccc(Cl)c3)CC2)C1 +CN1CC=C(c2ccc(OC(F)(F)F)c(Nc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 +Cc1cn(-c2cc(F)c(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)cc2F)cn1 +CC1CCCN1CCCOc1ccc(C2=NNC(=O)C(c3ccccn3)C2)cc1 +CON=Cc1c(N)ncnc1Oc1ccc(NC(=O)NCCCCN2CCCC2)c(Cl)c1 +CCC(=O)Nc1cccc(CCN2CCN(c3cccc4nc(C)ccc34)CC2)c1 +Cc1csc(-c2cc(-c3cccn3C)c3n(c2=O)CCCc2ccncc2-3)n1 +CN(CCCc1cccc(Oc2ccccc2)c1)C(=O)CP(=O)(O)O +CCc1cc2c(=O)n(N)c(SCCCN3CCN(c4ncccn4)CC3)nc2s1 +Cc1onc(-c2ccccc2)c1CN1CCCC(NC(=O)N2CCc3[nH]nc(-c4ccncc4)c3C2)C1 +Clc1ccccc1-c1cccc(-n2nnc(-c3ccccn3)n2)c1 +O=C(Nc1ccc2c(c1)NC(=O)N(CCO)C2)NC1CC(CF)(CF)Oc2c(F)cccc21 +N#Cc1nc(N2CCC(S(=O)(=O)c3ccc(N4CCN(C5CC5)CC4)cc3Cl)C2)cc(C(F)(F)F)n1 +CSc1nc(NCc2cccnc2)c(C(=O)O)c(SCc2ccccc2)n1 +COC(=O)c1cnc(N2CCN(c3nnc(C(O)c4ccccc4)c(C)c3C)CC2C)cn1 +CCc1noc(C)c1C(=O)N1CCSC1=Nc1cccc(Cl)c1C +O=c1oc(OCCCCC2CCCCC2)c(Cl)c2ccccc12 +CC(C)CNC1=NC(=Cc2ccc3c(c2)OCO3)C(=O)N1C +COc1ccc2c(c1)CCC(=O)C2=Cc1ccc(Cl)cc1 +CC(=NNC(=O)c1cc(Br)ccc1O)c1cc2ccccc2s1 +CCC(=O)c1ccc(C(=O)c2ccc(N(CC3CC3)c3ccc(Cl)cc3)cn2)cc1C(=O)O +COc1ccc(-c2nc(C(C)Sc3nc(N)cc(N)n3)c(C)s2)cc1OCCF +CCOC(=O)CCC(NC(=O)c1ccc(CNc2ccc3nc(N)nc(N)c3c2)cc1)C(=O)OCC +CCC(CC)c1ccc(Cl)c2nc(Nc3c(C)cc(Cl)cc3Cl)n(C)c12 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNCC(C)=O +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(C(F)(F)F)n[nH]c4c3)CC1)C2 +CC(C)(C)c1ccc2c(c1)CC(NC(=O)Nc1cccc3scnc13)C2 +CC(=O)N(C)Cc1ccc(-c2cc(OCc3ncccc3C(N)=O)c3cccnc3c2)cc1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2CCC(=O)Nc1ccccc1 +CC(C[Si](O)(O)C(Cc1ccccc1)NC(=O)c1ccccc1)C(=O)N1CCCC1C(=O)O +Cc1ccn2ncnc(Nc3ccc4c(cnn4Cc4ccccn4)c3)c12 +Cc1ccc2c3c(ccc(N(C)Cc4ccc(S(=O)(=O)c5ccccc5)cc4)c13)N=C2N +CCC#CCOc1ccc(S(=O)(=O)N(C)c2c(C)cc(Br)cc2C(=O)NO)cc1 +O=C(NC(CCCCCCSSc1ccccn1)C(=O)Nc1ccccc1-c1ccccc1)OCc1ccccc1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccc(Br)o1 +Cc1cc(C)n2cc(CSc3nc(-c4ccccc4)cn3C)nc2n1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2ccccc2C1 +Cn1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CC(O)C3)n2)cn1 +Cc1nnc(CNc2cc(OCC3CC3c3ccc(OC(F)F)cn3)nn(C)c2=O)s1 +CCCOc1ccccc1C(=O)NC(=O)NC1CC2CCC(C1)N2C +c1ccc(CNc2nccc(-n3cnc4ccccc43)n2)cc1 +CC12C=CC(=O)CC1CCC1C2CCC2(C)C(O)CCC12 +CC(C)C1CCC(N(Cc2ccc(C(=O)NCCC(=O)O)cc2)C(=O)Nc2ccc(OC(F)(F)F)cc2)CC1 +O=C(C=Cc1ccc(O)cc1)CC(=O)C=Cc1ccccc1-c1cccc2ccccc12 +COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1ccc(F)cc1 +CSc1nn2cc(-c3nc4ccc(OC(C)C)cc4o3)nc2s1 +O=C1N(CCCCCOc2ccc(-c3ccc(Cl)cc3)cc2)CCN1c1ccncc1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1nc(CS(=O)(=O)c2ccccn2)no1 +CN1CCC(c2ccc(-c3nc4c(C(N)=O)cccc4[nH]3)cc2)CC1 +COc1cccc2c1CCC=C2CCCN1CCN(c2ccccn2)CC1 +CCCCC(=O)OCc1ccc(C(CN)C(=O)Nc2ccc3cnccc3c2)cc1 +O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2cc(F)c(F)cc2F)CC1 +CC(C)(C)NC(=O)Nc1cnc2ccc(N3CCCC3c3cc(F)ccc3F)nn12 +COCC(C)n1cc(C#N)c2cc(-c3nc(C)c(C(=O)O)s3)ccc21 +N#Cc1cc(F)cc(S(=O)(=O)c2sc3ncc(N)cc3c2-c2cccc(F)c2)c1 +FC(F)(F)c1nnc2c(Sc3ccccc3)nc3ccc(Cl)cc3n12 +Cc1cc(NC(=O)Nc2ccc(N(CCCl)CCCl)cc2)cc(Nc2c3ccccc3nc3ccccc23)c1 +COc1ccc(CN(Cc2ccc(SC)cc2)c2ccc3nc[nH]c3c2)cc1 +NC1CN(C(=O)c2ccc(-n3cncn3)cc2)CC1C(=O)N1CCCC1 +N#CCNC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COc1cc(Nc2cc(C#N)cn(C(C)c3ccc(F)cc3)c2=O)ccc1-n1cnc(C)c1 +CC1(COc2nc(C(=O)NC(C)(C)c3nccs3)ccc2N2CC(F)(F)C2)COC1 +CCOCCc1sc[n+](CCCCCCCCCCCC[n+]2csc(CCOCC)c2C)c1C +CC(C)=CCC=C(C)CCCC(C)=CCCSC(C)CCC=C(C)CCC1OC1(C)C +O=C(NCc1cccnc1N1CCCCC1)c1cncc(-c2ccc(Cl)cc2)c1 +Cc1noc(-c2cc3cc(-c4nc(C(=O)NCc5ccc(C(O)C(F)(F)F)cc5)[nH]c4C)ccc3[nH]2)n1 +COc1ccc(Cc2ccc3c(-c4cnn(C)c4)cc(C(N)=O)nc3c2)cn1 +c1ccc2c(c1)c1cc[n+]2CCCCCCCCCC[n+]2ccc(c3ccccc32)NCCCCCCCCCCN1 +COc1cccc(-n2cc(C(=O)N3CCN(c4ccc5cnccc5c4)CC3)nc2-c2ccc(C)cc2)c1 +COc1ccccc1OCCN1CCN(c2cnn(CCCCCN3CCN(c4ccccc4OC)CC3)c(=O)c2Cl)CC1 +COC(CCS(=O)(=O)c1ccc2ccccc2c1)C(=O)NC1CCCc2cc(CN3CCCCC3)ccc21 +Cn1ccc(Nc2ncnc3ccc(Oc4c(Cl)cccc4S(C)(=O)=O)cc23)n1 +COCc1cc2c3cccnc3cc(CCc3nc(-c4ccccc4)cn3C)n2n1 +O=C(O)C1=C(C(=O)Nc2c(F)cccc2F)CCC1 +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cc(C)cc(CN)c3)cc2N=C(N)C1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(CN2CCC(N)C2)CC1 +CN(C(=O)Cc1ccc(Cl)c(Cl)c1)C(CN1CCCC1)c1ccccc1 +CC(Nc1ncnc2[nH]c(-c3ccc(NC(=O)CCCC(=O)NO)cc3)cc12)c1ccccc1 +NC(Cc1cnc[nH]1)C(=O)N1Cc2[nH]c3ccccc3c2CC1C(=O)O +Cc1cc(C(N)=O)ccc1-c1cc(C(F)(F)F)nc2c(-n3cnc(-c4cnn(C(F)F)c4)c3)cccc12 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+Cn1nc(S(N)(=O)=O)sc1=NC(=O)CNCCNCC(=O)O +CC(Cc1ccc2c(c1)OCO2)CN1CC2CCCCC2C(C(=O)N2CCN(c3cccc(F)c3)CC2)C1 +O=C(Nc1ccc([N+](=O)[O-])cc1O)Nc1ccccc1Cl +Cc1ccc(NC(=O)Nc2cc(C(F)(F)F)ccc2F)cc1Nc1ccc2c(c1)NC(=O)C2=Cc1ccc[nH]1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n3n2CCCC3)n1)C(C)(C)O +CCC1=CC2Cc3nc4cc(C)cc(C)c4c(N)c3C(C1)C2 +CC(C)n1ncnc1-c1cn2c(n1)-c1ccc(-c3ccccc3S(N)(=O)=O)cc1OCC2 +CCC(NC(=O)c1cc2[nH]nc(NC(=O)c3ccc(N4CCN(C)CC4)cc3)c2s1)c1ccccc1 +O=C(CNc1cccc(O)c1)Nc1nc2ccc3[nH]ncc3c2s1 +COc1c(OC)c2c(c(CCN(C)C)c1SC)Sc1c(OC)c(OC)c(SC)c(CCN(C)C)c1S2 +CCc1cc(-c2noc(-c3cc(C)c(CNCC(C)C)s3)n2)cc(C)c1OCC(O)CNC(=O)CO +COc1cc(F)ccc1-c1nc(Nc2cc(F)cc(CS(C)(=N)=O)c2)ncc1F +O=C(NO)C1CN(C(=O)c2ccccc2)CCCN1S(=O)(=O)c1ccc(Oc2ccccc2)cc1 +CC(C(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1)N1CCCC1 +CC(C)Oc1cccc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +CC(C)S(=O)(=O)Nc1ccccc1N1CCN(C(=O)C(CCCc2ccccc2)NC(=O)C(C)(C)N)CC1 +O=C(NC(C(=O)N1CCC2OCC(=O)C21)C1CCCCC1)c1cccc(-n2cnnn2)c1 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+CCCCn1c(=O)[nH]c2cccc3nc4c(c1c32)Cn1c-4cc2c(c1=O)COC(=O)C2(O)CC +CN(C)c1ccc(-c2cn(-c3ccc(OCCF)cc3)nn2)cc1 +Nc1nc2c(N)[n+]3cnc2n1C1OC(COP(=O)(O)OP(=O)([O-])OCC2SC3C(O)C2O)C(O)C1O +O=C(NCc1ccc(Cc2ccsc2)s1)C(O)C(O)C(=O)N1CCCC1c1cccc(Cl)c1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)N1CC2CN(CCC(NC(=O)C3CCCC3)c3ccccc3)CC2C1 +CS(=O)(=O)N1CC(C(=O)Nc2ccc(Cl)cc2)C(C(=O)Nc2c(F)cc(-n3ccccc3=O)cc2F)C1 +Oc1ccc2nc(-c3ccccc3)n(-c3ccccc3)c2n1 +CCCCCCCC#CC1(C(F)(F)F)CC(c2ccc(C)cc2)=C(c2cn[nH]n2)C(=O)N1 +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1ccccc1 +CCN1CCN(Cc2ccc(Nc3nccc(-c4sc(NC5CCCC5)nc4C)n3)nc2)CC1 +Cc1nc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C +Cc1cccc2c1Oc1c(cccc1C(=O)NCCN(C)C)O2 +CS(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CN(C(=O)Nc4cc(F)ccc4F)C3)cc2C(N)=O)cc1 +Cc1ccn2ncc(C=NN(C)S(=O)(=O)c3cc([N+](=O)[O-])ccc3C)c2c1 +COCCn1c(C)c(C)sc1=NC(=O)C1C(C)(C)C1(C)C +O=C(CCC1CCCCC1)NC(Cc1ccccc1)C(=O)N1CCCC1C(=O)N1CCCCC1 +CS(=O)(=O)Nc1ccc2ccc3ncc(-c4cccnc4)cc3c(=O)c2c1 +O=C(N1CCCCC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +Cc1cc(SCC(F)(F)COc2ccc(C(F)(F)F)cc2)ccc1OCC(=O)O +Fc1cccc(CNc2ccc(Cl)c(-c3ccnc4[nH]c(C5CCCNC5)cc34)n2)c1 +C=CC1CN2CCC1CC2C(OCc1cn(-c2ccc(Cl)cc2)nn1)c1ccnc2ccc(OC)cc12 +Cc1ncc(Cn2cc(CCOP(=O)(O)OP(=O)(O)O)nn2)c(N)n1 +CNC(=O)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 +COC(=O)c1cccc(NC(=O)Nc2cccc(C#N)c2)c1CN1CCC(Cc2ccc(F)cc2)CC1 +CCCCC1Nc2ccc(C(C)C)cc2C(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc2c(=O)cc3n(CCCN(C)C)c4ccccc4nc-3c2c1 +O=C(Nc1ccc(-c2nc3cc(NC(=O)C4CC4)ccc3[nH]2)cc1)c1ccccc1Cl +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(Cl)c(C)c3)nc(C(C)O)c12 +CC1CN(CCC(=O)C2CCCCC2)CCC1(C)c1cccc(O)c1 +Cc1cc(S(=O)(=O)NCc2ccccc2)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +Cc1c(C(=O)NC2CCN(C(=O)NC(C)C)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(C=CCN1CCCCC1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC1CCOC1 +NC(C(=O)N1CCN(c2ccc3[nH]ncc3c2)CC1)c1ccc(Cl)cc1 +NC1=NC(CF)(c2cc(Oc3ncccc3Cl)ccc2F)CC(C(F)(F)F)O1 +Cc1ccc(F)c(-c2nc(C(=O)Nc3cnn(C)c3N3CCCC(N)CC3)c(N)s2)c1F +CCCCOC(=O)NC(CNC(=O)CC1CC(c2ccc(C(=N)N)cc2)=NO1)C(=O)OC 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+COc1cc(C(=O)NCC(O)c2cccc(Cl)c2)ccc1-c1cn[nH]c1 +O=C(c1cc(Cl)ccc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncon2)c1 +Cc1noc(C)c1S(=O)(=O)NC(=O)COc1cccc2[nH]cc(S(=O)(=O)c3ccc4ccccc4c3)c12 +COc1cc(C=C2CCCN3C2=NOC3(c2ccc(F)cc2)C(C)O)ccc1-n1cnc(C)c1 +COc1cc(OC)c(C(=O)C=Cc2cccc([N+](=O)[O-])c2)c(OC)c1 +COCCN(Cc1ccc(-c2ccc(Cl)cc2)cc1)C(=O)Cn1cc(Cc2cnn(C)c2)c(=O)nc1SCc1ccc(F)cc1 +O=C(c1ccnc2ccccc12)N1CCC(N2CCC(Oc3ccc(S(=O)(=O)c4ccc5c(c4)OCO5)cc3)CC2)CC1 +NCCCC(=O)Nc1nc2nn(CCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +CC1(Nc2ccc(C(=O)NO)cc2)CCN(c2ccc3ncccc3c2)C1=O +N=C(N)NCCCC(NC(=O)Cn1c(-c2ccccc2)c(Cl)nc(NCCc2ccccc2)c1=O)C(=O)c1nccs1 +CN(C)C(=O)n1nnc(CNC(=O)CCCCCCCc2ccccc2)n1 +COc1ccc(S(=O)(=O)N2c3ccc(Cl)cc3C(O)(c3ccccc3Cl)C2C(=O)N2CCCC2C(N)=O)cc1OC +Cc1oc(-c2ccc(C(F)(F)F)cc2)nc1CCCCC1COC(C)(C(=O)O)OC1 +COc1ccc(C(NC(=O)CC2CCN(Cc3ccn(-c4ccc(C(F)(F)F)cc4)c3)CC2)c2ccc(F)cc2)cn1 +COc1cc(NS(C)(=O)=O)ccc1S(=O)(=O)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1Cl +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(OC(=O)c2ccc(C)cc2)c1 +COc1ncc(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)cn1 +CCc1cc(O)c(OC)c(C(=O)NCC2CCCN2CC)c1F +CC1(CNC(=O)c2ccc(C#Cc3cccc(F)c3)cn2)COC1 +CCc1cc(C)n(CC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)n1 +CN1CCC(NC(=O)Nc2cccc(C#N)c2)CC1c1nc2ccccc2[nH]1 +COc1cccc2ccc(COc3ccc(-c4nn(C)cc4-c4ccncc4)cc3)nc12 +Cc1cc(-c2ccccc2)cc(=O)n1CCC(C)(C(=O)NO)S(C)(=O)=O +Cc1cccc(NC(=O)NC2N=C(N3CCN(C)CC3)c3ccccc3N(C)C2=O)c1 +CCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc(B(O)O)cc1)c1ccccc1 +CCN(c1cc(C(F)(F)F)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +Cc1ccc(C2=C(C(=O)Nc3nn[nH]n3)C(=O)NC(c3ccc(C4=CCCC4)cc3)(C(F)(F)F)C2)cc1 +COc1cnc(C(=O)Nc2ccc(F)c(C3(C)CS(=O)(=O)C4(CCN(C)CC4)C(=N)N3)c2)cn1 +CC(C)c1csc(Nc2ncc(SCCn3ccnc3)cc2OCc2ccccc2)n1 +O=C1NCCN1c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +COc1ccc(-c2[nH]c(-c3cccs3)nc2CCNS(=O)(=O)N(C)C2CCN(Cc3ccc(Cl)c(Cl)c3)C2)cc1 +CC(C)Nc1nc2ccc(-c3[nH]cnc3-c3ccccc3)cc2s1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)CCC(F)(F)F +CCN(C(=O)OCC(=O)Nc1ccc(-c2ccc(CC(=O)O)cc2)cc1Cl)c1ccc(C(C)(C)C)cc1Cl +O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccc(F)cc1 +CN(C)c1ccc(O)c(C(=O)c2ccc(C(=O)NC3CCCNCC3NC(=O)c3ccncc3)cc2)c1 +COc1ccc(N(Cc2cccc(C#N)n2)C2CCN(C(C)CCNC(=O)c3c(C)cc(F)nc3C)CC2)cc1 +CCOC(=O)c1c(CSc2ccccc2Cl)[nH]c2c1cc(O)c1ccccc12 +Cn1cc(-c2ccc3nc(NC(=O)c4ccccc4)c(Cl)n3n2)c(-c2ccc(F)cc2)n1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2cccc3ccccc23)[nH]c1=O +CC1CN(Cc2ccc(C=Cc3n[nH]c4cc(C5CC56C(=O)Nc5ccccc56)ccc34)cc2)CC(C)O1 +NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1ccc2cn[nH]c2c1 +Cn1cc(C(=O)N2CCC(NC(c3ccc(C(F)(F)F)cc3)c3cccnc3)CC2)c(C(F)(F)F)n1 +Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2ncccc2F)s1 +CCC(C1=C(O)OC(CC(C)C)(CC(C)C)CC1=O)c1cccc(NS(=O)(=O)c2cn(C)cn2)c1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cn(Cc4ccccc4)nn3)c(C(=O)O)n1)CC2 +CCCc1nc(CC)c(C(N)=O)n1Cc1ccc(-c2ccccc2S(=O)(=O)Nc2onc(C)c2C)c(COCCF)c1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(Cc3ccc(Br)cc3)CC2)CC1 +CC1CCN(C(c2ccc(C(F)(F)F)cc2)c2ccc(C(C)C(=O)O)cc2-c2ccc(C(F)(F)F)cc2)CC1 +CCc1nc(Nc2ccc(-c3cnco3)c(OC)c2)oc1-c1ccccc1 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+O=C1C(N2CC2)=CC(=O)c2c(OS(=O)(=O)c3cccc4cccnc34)cccc21 +Cn1nccc1-c1cc(NC(=O)Nc2ccccc2Cl)ccc1OCCN1CCCCC1 +COc1ccc(Cl)cc1S(=O)(=O)Nc1cc(C(=O)Nc2ccc(C(=O)O)cc2)cn(C)c1=O +CCCCCCCCCCCCn1c(N)c(N)c(=O)n(C)c1=O +CCC(=O)NCCn1c(C(=O)OC)cc2ccc(OC)cc21 +COC(=O)N1C2CCC1CC(O)(C#Cc1cccc(C)n1)C2 +O=C(CCCNC1C(O)C(O)C(O)C(O)C1O)NC12CC3CC(CC(C3)C1)C2 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)c2cc1OCCOC +O=C(c1cccc(F)c1Br)N1CC2CC(Oc3ccc(C(F)(F)F)cn3)C1C2 +CN(CCN1CCOCC1)c1ccc2c(n1)sc1nc(-c3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)cn12 +O=C(NC(c1cccnc1)C(F)(F)F)c1cc(OCc2ccc(F)cc2)c(Cl)cn1 +Cc1ccc(CCN2C3=NCC(Cc4ccc(O)cc4)N3CC2CCCNC(=O)C2CCC2)cc1 +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4ccc(Cl)nc4)c3)ncnc12 +O=C(NCC(=O)N1CCCC1B(O)O)c1c(Cl)cccc1Cl +O=C1C(N2CCC(c3ccc(O)cc3)C(F)(F)C2)CCN1Cc1ccc(F)c(Cl)c1 +Cn1cnc2ccc(-c3c(-c4ccccn4)nn4c3CCC4)cc21 +N=C(N)c1ccc(-c2ccc3cc(-c4cc(C(=N)N)ccn4)[nH]c3c2)cc1 +CCCNC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +N=C(N)N1CCCC(NC(=O)CN2CCCCC(N3C(=O)c4ccccc4CS3(=O)=O)C2=O)C1O +O=C1NCC(c2ccc(F)cc2)C12CCN(C1(c3ccc(F)cc3)CCCCC1)CC2 +NC(=O)C=Cc1ccc(Oc2c(-c3ccc(O)cc3)sc3cc(O)ccc23)cc1 +O=C(Cn1nc(C2CCCCC2)cc(Cc2ccco2)c1=O)NCCc1cccc(F)c1 +COCC(NC(=O)N1CC(=O)Nc2cc(Cl)cnc21)c1ccc(OC(F)(F)F)cc1 +CNC1CCc2c(c3ccccc3n2S(=O)(=O)c2cccc(C(F)(F)F)c2)C1 +Cc1cc(-c2n[nH]c3cc(NC(=O)N(C)Cc4cccnc4)ncc23)ccn1 +CC(CCN1CCN(c2ccc(F)cc2)CC1)NS(=O)(=O)c1ccc2ccccc2c1 +O=C(Nc1ccc2cc[nH]c2c1)c1c[nH]c2ccccc2c1=O +CC(C)Oc1ccc(-c2onc3c2CCc2cc(CNCCC(=O)O)ccc2-3)cc1C#N +Cc1nocc1C(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CCOc1ccccc1N1CCN(CCCn2ncc(N3CCN(CCOc4ccccc4OC)CC3)c(Cl)c2=O)CC1 +CCCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(C(=O)O)c(N)nc3ccccc23)cc1 +CSc1ccc(-n2c(-c3ccc(S(C)(=O)=O)cc3)cc(CC(=O)OCCCCO)c2C)cc1 +CC(C)N1CCC(N(C)C(=O)c2ccc(Cn3cnc4ccccc43)cc2)C1 +Nc1nc(NCC2CCCN2Cc2c(F)cc(F)cc2F)nc2nc(-c3ccco3)nn12 +Cc1cc(C)n(CCNCc2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)n1 +C=CC(=O)Nc1cc(Cl)ccc1C1CCNc2c(C(N)=O)c(-c3ccc(OCC4CC4)cc3)nn21 +CCCn1c(Nc2cccc(C(F)(F)F)c2)nc2nc(C3CCCC3)[nH]c2c1=O +Cc1nn(-c2ccccc2)c2c1C(c1ccc(O)c(O)c1)N1C(=N2)C(Nc2ccccc2)=Nc2ccccc21 +O=C(CSc1ccc(F)cc1)NC(Cc1c[nH]cn1)C(=O)NCCc1ccccc1 +Cc1ccc(CC(=O)Nc2ccc(NC(=O)C=Cc3ccc(-c4ccc5ccccc5c4)o3)cc2C(=O)c2ccccc2)cc1 +N#Cc1ccc(NC(=O)C(CN2CC(O)C2)Oc2ncnc3c2cnn3-c2c(Cl)cccc2C#N)nc1 +CCOc1cc(CN2CCCC(NC(=O)c3cncc(C)c3)CC2)ccc1C +CNC(=O)c1cnc(NCCc2ccc(O)cc2)nc1Nc1cccc(C)c1 +Cc1cc(SC2=C(O)OC(CCc3ccc(O)cc3)(C(C)C)CC2=O)c(C(C)(C)C)cc1NC(=O)c1cccnc1 +O=C(Nc1ccc(CCc2ccc(O)c(O)c2)cc1)c1ccc(Cl)cc1O +CC(=O)N(C)Cc1ccc(CN2CCN(c3ccccc3OC(C)C)CC2)n1C +O=C(c1ccc(Br)s1)C1CCN(C2Cc3ccccc3CC2O)CC1 +CC(C)(C)c1ccc(Oc2cccc(COc3ccccc3CCC(=O)OCCCOP(=O)(O)OCC(N)C(=O)O)c2)cc1 +N#Cc1ccnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4ccnc(N)c34)c(F)c2)c1 +Cc1cccc(C(=O)N2CC(C)OCC2Cc2cccc(-n3nccn3)c2)c1-n1nccn1 +CS(=O)(=O)N1CCc2oc(-c3ccnc(Nc4ccc(OCCN5CCCC5)cc4)n3)cc2C1 +CN(C)C1CCC(n2cc(C(N)=O)c(Nc3ccc(Cl)cc3)n2)C(C#N)C1 +O=C(O)c1cc(-c2ccc(OC3CCCCC3)c(Cl)c2)ncn1 +c1ccc2c[n+](CCCCCCCCCC[n+]3ccc4ccccc4c3)ccc2c1 +O=C(NCc1cccnc1)C1CN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CCN1C(=O)NC1CCCCC1 +Cc1cc(C)c(-n2ccn3nc(-c4cccnc4)cc23)cc1NC(=O)c1cccc(OC(F)(F)C(F)F)c1 +Cc1onc(C(=O)N2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)c1[N+](=O)[O-] +O=S(=O)(CC1CC1)NCCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N1CCC1)CC2 +COc1cc(C)c2c(c1)C(c1ccc(O)cc1)(c1ccc(O)cc1)C(=O)N2 +Oc1ccc2c3c1OC1C(OCc4ccc(-c5ccccc5)cc4)CCC4(O)C(C2)N(CC2CC2)CCC314 +CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]c(=NC(=O)c1cscn1)n2CCC(N)=O +OCc1cccc(-c2nc(N3CCOCC3)c3cc[nH]c3n2)c1 +CCCn1c2ccc(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +CC(OC1CN2C(=O)C(O)CC2C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +NC(=O)c1cc(N2CCNCC2CO)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +CCCCOP(=O)(CCCCC1(C(=O)NCc2ccccn2)c2ccccc2-c2ccccc21)OCCCC +Oc1ccc(Cn2cnc3ncc(-c4ccc(F)cc4)nc32)cc1 +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccc(C(F)(F)C(F)(F)F)cc4)O2)C3=O)cn1 +COC(=O)c1cccc(CC2=C(c3ccc4c(c3)OCO4)C(=O)OC2(O)c2ccc(OC)cc2)c1 +CCn1cc(-c2ccnc3[nH]c(-c4ccc(CN5CCCC5)cc4)cc23)c(-c2ccc(NC(=O)N(C)C)cc2)n1 +COc1ccc(C2CCN(CCCCc3ccccc3)CC2)cc1 +Oc1ccc2cc(-c3nc4ccc(O)cc4o3)ccc2c1 +O=C(O)c1ccc(-c2n[nH]c3c2Cc2cc(CN4CCOCC4)ccc2-3)cc1 +CCOc1cc(C(=CC#N)c2ccc(OC)c(O)c2)ccc1OC +COc1c(C(=O)NCCN2CCN(c3ccc(Cl)cc3Cl)CC2)cc(Br)c2ccccc12 +C=CC(=O)NCc1coc(-c2c(N)ncnc2Nc2ccc(Oc3ccc(F)cc3)c(Cl)c2)n1 +CC(C)c1ccc(-n2c3ccccc3n3c(CN(CC4CC4)CC4CC4)c(C(F)(F)F)nc23)c(Br)c1 +Cc1cc(C=C2C(=O)Nc3ncc(F)cc32)c2ccccc(OCCCN3CCOCC3)c1-2 +CC(=O)N1N=C(c2ccc(C)cc2)CC1c1c(C)nn(-c2ccc(S(N)(=O)=O)cc2)c1Cl +CNC(=O)N1CCC(NC(=O)Nc2nc(C)c(C(C)=O)s2)C(CN2CCCC(Cc3ccc(F)cc3)C2)C1 +O=C(Nc1ccccc1Cl)c1ccc(-c2cc3scnc3cc2Cl)s1 +CC(NC(=O)c1ccc(C#Cc2cccc(F)c2)nn1)C(C)(C)O +Cc1cc(C(=O)N(CC2CC2)CC2CCCO2)ccc1-c1ccccc1 +O=C(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)C1CC(Cl)C1 +N=C(N)c1cccc(C2=NOC(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3)C2)c1 +FC(F)n1c2ccccc2c2cc(CCOc3ncccc3-c3cncnc3)cnc21 +COc1ccc(CC(=O)NCC2CCCN(Cc3ccc(SC)cc3)C2)cc1 +COc1cc(CNC(=S)NC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)cc(Cl)c1O +COCC(C)Oc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C)n1 +O=C(NC1C[N+]2(CCCOc3ccccc3)CCC1CC2)C(c1cccs1)c1cccs1 +CC(C)(Cc1ccc2ccccc2c1)NCC(O)COC(c1ccccc1)c1ccccc1 +COc1ccc(C(=O)NCCCCN2CCc3ccc([N+](=O)[O-])cc3C2)c(OC)c1OC +Cc1cc(C)c(Nc2nc3ccccc3n3cncc23)c(Cl)c1 +Cn1c(=O)c2[nH]c(-c3cccc(OCCN4CCCCC4)c3)nc2n(C)c1=O +CC(C)CN1CCC(CNC(=O)c2cc(Cl)cc3[nH]cnc23)CC1 +CN1CCN(Cc2cc3c(nc2C=O)N(C(=O)Nc2cc(NC45CC(C4)C5)c(C#N)cn2)CCC3)C(=O)C1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=S)N1CCCS(N)(=O)=O +O=C(CO)NC(CNc1cc(-c2ccncc2)c(-c2cccc3ccccc23)nn1)Cc1ccccc1 +Cc1cccnc1CNC(=O)c1cc(-c2ccccc2)nc(N)n1 +O=[N+]([O-])c1c(Nc2cc(F)cc(C(F)(F)F)c2)ccc2nonc12 +COCCc1sc[n+](CCCCc2ccc(CCCC[n+]3csc(CCOC)c3C)c3ccccc23)c1C +COCCn1c(-c2ccc(C(C)C)cc2)nc2c(Br)c(Cc3cccnc3SC)cc(OC)c21 +OCC1OC(c2cc(Cc3ncc(-c4ccoc4)s3)c(Cl)cc2Cl)C(O)C(O)C1O +N#Cc1cc2c(cc1Cc1cccc(Cl)c1Cl)c(=O)c(C(=O)O)cn2CCO +CN=C1NC(=O)C(=Cc2c[nH]c3ccc(Br)cc23)N1C +N#Cc1ccc(OC(c2ccccc2)C2CCNCC2)cc1Cl 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+CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cc(Cn3c(=O)[nH]c(=O)c4ccccc43)cnc2Cl)C1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(N3CCOC(CO)C3)c2c1=O +O=[N+]([O-])c1cc2nc(C(F)(F)F)[nH]c2cc1[N+](=O)[O-] +CN(Cc1ccc(F)cc1)C(=O)Cc1nc(S(=O)(=O)Cc2ccccc2)c2ccccn12 +COc1ccc(-n2[nH]c3c(cnc4cc(OC)ccc43)c2=O)cc1 +CCCC(Cc1ccc(OC)c(C(=O)NCc2ccc(C(F)(F)F)cc2)c1)C(=O)O +O=C(c1ccccc1-n1cccn1)N1C2CCC1C(COc1ccc(F)cn1)C2 +COc1cc2c(cc1CNC1CCCNC1c1ccccc1)C(C(F)(F)F)OC2 +O=c1c(-c2ccccc2)c[nH]c2c(-c3cccc(C(F)(F)F)c3)cnn12 +Cc1cc(SC2=C(O)OC(CCc3ccccc3)(C(C)C)CC2=O)c(C(C)(C)C)cc1OS(=O)(=O)c1cccnc1 +CC(C)CC(=O)OCC(CO)OC(=O)CC(C(C)C)C(C)C +CC1CCCN1C1CCN(c2ccc(N3CCC4(CCN(S(=O)(=O)c5ccccc5)CC4)C3=O)cc2)CC1 +O=C(OCC1CCc2ccccc2N1S(=O)(=O)c1ccc(Cl)cc1)N1CCC(N2CCCC2)CC1 +COc1nc(N2CC3C(=O)N(C)C(N)=NC3(c3ccc(F)cc3F)C2)nc(C2CC2)c1F +C(#Cc1ncnc2scc(-c3ccccc3)c12)COCCN1CCCC1 +COc1cc(CC2COCC2Cc2ccc3c(c2)OCO3)cc(OC)c1OC +O=C(c1cc[n+]([O-])cc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +COc1cccc(-c2n[nH]c(Cc3cccc(Br)c3)n2)c1 +C#CCN1CC(NC(=O)c2ccc(Cn3c(C(C)(C)C)nc4ccccc43)cc2)C(C(=O)NO)C1 +N#CC1(NC(=O)C2CCCCC2C(=O)N2CCN(c3nc4c(s3)COCC4)CC2)CC1 +CCN(CC)C(=O)C1CCC2C3CC=C4N(N)C(=O)CCC4(C)C3CCC12C +O=C(O)C1CCN(C(=O)C=Cc2ccc(Sc3ccc4c(c3)OCCO4)c3ccccc23)CC1 +CC(=O)N1CCN(Cc2cn3cc(-c4cccc(O)c4)nc(N4CCOCC4)c3n2)CC1 +C=C(C)c1cccc(C(C)(C)NC(=O)N(C)c2ccc(Cl)cc2)c1 +CN1CCN(CCCN(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)C2CCC3(c4nccs4)CC23)CC1 +O=C(c1ccc(O)cc1O)N(Cc1ccccc1)c1ccc(-c2ccccc2Cl)cc1 +O=C(NCc1cc2ccccc2[nH]1)N1CCc2cnc(NC3CCOCC3)nc2C1 +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3ccnn3C)nc12 +O=C(O)c1cccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOCC4)N3)n2)c1 +COc1ccc(C2(Cc3ccccc3)CCN(C(=O)OC(C)(C)C)C2=O)cc1OC1CCCC1 +CN(C(=O)CSc1nc(-c2ccccc2)cn1N)C(c1ccccc1)c1ccccc1 +Clc1ccc(OCCNCc2cccs2)c2c(Cl)c[nH]c12 +COc1ccc(CS(=O)(=O)C=Cc2c(OC)cccc2OC)cc1N +O=c1n(Cc2cnn(-c3ccccc3Cl)c2)nc(-c2ccc(Cl)cc2)n1CC(O)C(F)(F)F +COC(=O)C=Cc1oc(=O)c(COC(C)=O)c(OC)c1CO +Cc1cc(CCC(=O)O)ccc1-c1noc(-c2ccc(CC(C)C)nc2)n1 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+CC(C)S(=O)(=O)NC1Cc2ccc(Cn3cc(CO)c(C(F)(F)F)n3)cc2C1 +Cc1nc(C#Cc2ccc(-c3ccc(F)c(F)c3)nc2)cs1 +O=C(Nc1ccccc1)N1CCN(Cc2cccc(S(=O)(=O)c3ccc(Cl)cc3)c2)CC1 +COc1ccc(S(=O)(=O)NCc2ccc(-c3ccc(CN(C)CCO)cc3)cc2)cc1 +N=C(N)c1ccc2cc(-c3cccc(OCCCOc4ccccc4)c3)oc2c1 +CCCCN(C(=O)c1ccccc1Cl)c1nnc(-c2cc(C)c(CN3CC(C(=O)O)C3)c(C)c2)s1 +CNC(=O)c1ccc(Nc2nc3ccc(C(=O)N(CCC(C)C)CCC(C)C)cc3n2CCCN2CCCCC2)cc1 +CN(CC(=O)Nc1ccc(S(=O)(=O)N=c2sc(S(N)(=O)=O)nn2C)cc1)C(=N)N +CCOc1c(Br)cc(OC)cc1CNCCCNc1nc(O)c2ccccc2n1 +COc1ccc(C=C(C)C(O)c2cc(OC)c(OC)c(OC)c2)cc1O +CCC(O)(C(=O)Nc1nnc(CCCCc2nnc(NC(=O)C(O)(CC)c3ccccc3)s2)s1)c1ccccc1 +CC(=O)NC1CCN(c2ncnc(C)c2C#Cc2ccc(N)nc2)CC1 +COc1cc(C(=O)NCC(C)(C)CN(C)C)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +CNc1nnc(-c2ccc3[nH]cc(-c4cnc5ccccc5c4)c3c2)s1 +CCCCNCc1ccc2n1-c1ccccc1SC2c1ccc(OC)cc1OC +CS(=O)(=O)c1cccc(-c2cc3c(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)ncnc3s2)c1 +O=C(CC(Cc1ccc(Br)cc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)C(S)Cc1ccccc1 +O=C(O)Cc1csc(=NC(=O)CS(=O)(=O)c2ccc(-c3ccccc3)cc2)n1O +O=C(Nc1ccc(C2CCNC2)cc1)Nc1ccc(Cl)nc1 +CN(C)CC(NC1CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1)c1ccccc1 +CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(NCC(C)O)c2c1Cl +CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(F)cc12 +COc1ccc(CN2CCN(CCCOc3ccc(C(=O)NC(=N)N)cc3NC(=O)c3ccccc3)CC2)c(OC)c1OC +Oc1ccc2c(c1O)-c1cccc3c1C(C2)N(CCCl)CC3 +COc1ccc(-n2ncc3c(NCC(C)NS(=O)(=O)c4c(C)cc(C)cc4C)cc(C)cc32)cc1 +COc1ccccc1N1CCN(CCCCN2C(=O)c3cccc4cccc2c34)CC1 +CS(=O)(=O)N1CCc2c(c(-c3ccc(Cl)c(Cl)c3)nn2CCCN2CCC(n3c(O)nc4ccccc43)CC2)C1 +O=C(OC1CCCC1Cc1ccc(O)cc1)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1 +CCOC1CCc2nc3cc(Cl)ccc3c(NCCCCCCCCCNc3c4c(nc5cc(Cl)ccc35)CCC(OCC)C4)c2C1 +N#Cc1ccc(CNC(=O)C2COc3ncccc32)c(Cl)c1 +O=C(Nc1ccccc1Cl)N1CCN(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CN(CCOCCNC(=S)NC(=O)c1ccc(Cl)c(Cl)c1)Cc1ccccc1 +CC1Cn2c(nnc2C(F)(F)F)CN1C(=O)c1cccc(C(F)(F)c2n[nH]c(=O)c3c2CCCC3)c1 +COc1ccc(N2C(=O)c3c(Cl)ccc(NS(=O)(=O)c4ccc(C(C)(C)C)cc4)c3C2=O)c(OC)n1 +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1Cc1nnco1 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+Cc1cncc(-c2cc3c(cn2)cnn3-c2ccc(C(F)(F)F)c(N3CCCC(N)C3)n2)n1 +COc1ccc(C=CC(=O)NCCCCCNc2ccnc3cc(Cl)ccc23)cc1 +CC(C)N1CCN(C(CN2CCN(CCCc3ccc(-c4ccccc4)cc3)CC2)c2ccc(F)cc2)CC1 +COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC=Cc2ccccc2)C1c1cccc([N+](=O)[O-])c1 +COCC1(OC)c2ccccc2-c2ccc(C(=O)N=C(N)N)cc21 +Cc1cc(C)nc(N2CC3CN(C(=O)c4cccc5c4OCCCO5)CC3C2)n1 +O=C(O)c1cccc(S(=O)(=O)NCCc2ccccc2F)c1 +O=S(=O)(c1ccccc1)c1cn(C2CCNC2)c2ccccc12 +Cc1ccccc1Cc1ccc(N2CC(C)CC2CC(=O)O)cc1 +Cc1cccc(C)c1OCC(=O)NC(Cc1ccccc1)C(O)CN(CC(C)C)S(=O)(=O)c1ccc(N)cc1 +Cc1nc(N)cc(OCC(=O)C(C)(C)C)c1CNC(=O)c1cn(Cc2ccccc2)nn1 +COc1ccc(S(=O)(=O)N(CC2COC(=O)N2)CC(O)C(Cc2ccccc2)NC(=O)OC2COC3OCCC23)cc1 +CCN(CC)Cc1ccc(C(c2ccccc2Cl)n2cncn2)cc1 +CC(C)C(NC(=O)c1ccc(N=Nc2ccccc2)cc1)C(=O)NC(C=O)Cc1ccccc1 +O=C(Nc1ccnc(NC(=O)C2CC2)c1)c1c(Cl)cc(CO)cc1Cl +CCC(CC)(Cc1nc2c(F)cc(OCc3ccc(C)cn3)cc2n1Cc1ccc(OC(F)(F)F)cc1)C(=O)O +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2Cc3cn[nH]c3C2)c(-c2cncnc2)c1 +O=C1C(c2ccccc2)=[N+]([O-])c2cc([N+](=O)[O-])c(C=C(Cl)c3ccccc3)cc21 +N=C(N)NCCCC1C(=O)N(C(=O)c2cccs2)C1C(=O)O +CC(=O)N1N=C(c2cc(F)ccc2F)SC12c1cc(F)cc(F)c1OCC2CCN +CC(NC(=O)c1c[nH]nc1C(F)(F)F)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CCOC(=O)C1CCCN(C(=O)C(Cc2ccccc2)NC(=O)Nc2ccc(Br)cc2)C1 +O=C(NCc1ccc(-c2nccs2)cc1)C(O)C(O)C(=O)N1CCCC1c1cccc(Cl)c1 +CC(C)(C)NC(=O)C1CCN(Cc2cc(Br)cc(NC(=O)c3cccc(C(F)(F)F)n3)c2)CC1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1ccc(-c2ncc(C(F)(F)C(F)(F)F)[nH]2)c(Cl)c1 +CNC(=O)c1ccc(Nc2nc(OCCO)c3c(-c4ccc5nc(C)oc5c4)c[nH]c3n2)c(OC)c1 +O=C(c1ccc(Oc2nccnc2N2CCOCC2)cc1)c1nc2ccccc2s1 +Oc1ccc(-n2c(-c3ccccc3)nc3ccccc32)cc1 +COc1cccc(CN2CCC(CCCC(=O)c3ncco3)CC2)c1 +NS(=O)(=O)c1ccc(CCNc2nc(Oc3ccccc3)nc(Oc3ccccc3)n2)cc1 +CCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC(C)CCC(C)=O)S(=O)(=O)c1ccc(OC)cc1 +Cc1cc(-c2cn(CCN3CCC3)c(C3CCN(c4ncnc(N)c4C#N)CC3)n2)ccc1F +COc1cc(Nc2c(C#N)cnc3cc4cc(OCCN5CCOCC5)c(OC)cc4cc23)c(C)cc1Cl +CCCCCCOc1ccc(C=CC(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +N#Cc1ccc(-c2cc(C(=O)O)nn2-c2ccc(Cl)c(Cl)c2)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCOCC2)c(-c2ccc(CO)nc2)c1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(OCC(=O)OCC4CCCO4)cc3)ncc2Cl)c1 +COCc1ccccc1C(=O)N(CCc1ccc(Cl)cc1)C1CCC2(CC1)OCCO2 +c1ccc2c(c1)CN(CCCCc1nc3ccccc3s1)C2 +COc1cc(-c2ccc(-c3ccc(C(=O)O)cc3)[nH]2)nc2c(C(C)C)cccc12 +N=C(N)c1ccc(COc2ccc3c(c2)CCC(CC(=O)O)C3=O)cc1 +COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1cc2[nH]c(-c3ccco3)c(C3CCCCC3)c(=O)n2n1 +CCOc1ccc(CNC(=O)n2sc3ncccc3c2=O)cc1OC +COC(C(O)CO)C1OC(C(=O)O)=CC(NC(=N)N)C1NC(C)=O +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(Cl)c(-c2cncnc2)c1 +C=C(c1ccccc1)C12CCCC1CC(CCCCCC)=C2c1ccccc1 +O=C(Nc1ccc(F)c(-c2nc3ncccc3o2)c1)c1cscn1 +CC(NC(=O)CNC(=O)c1cccc(Cl)c1)c1ccccc1 +Fc1cc(-c2ccccc2)cn2c(Cc3ccc4ncccc4c3)nnc12 +CCCCCCCCCCCCCCCCC1=C(O)C(=O)C=C(O)C1=O +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4c5ccccc5CC4N(C)C)ncc23)ccn1 +COc1nn2cc(-c3cc4cc([N+](=O)[O-])ccc4o3)nc2s1 +CS(=O)(=O)CCCn1c(CN2C(=O)C(=NOCCF)c3cccnc32)nc2ccccc21 +CN(C)CCCc1ccc(OC(F)(F)F)c(Nc2ncc3c(n2)-c2ccc(Cl)cc2NC(=S)C3)c1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1c(-c2cccs2)nc2sccn12 +OC1C(O)C(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C2CC12 +CCC1(CC(=O)O)CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(CNS(=O)(=O)C2CCC2)C2CC2)C1=O +O=C1OC2(CCC(C(=O)Nc3ncc(-c4ccccc4F)cn3)CC2)c2ccncc21 +Cn1c2c(c3ccccc31)C(=O)c1c[n+]([O-])c3ccccc3c1C2=O +Cn1c(=O)c2c(cc(C=Cc3ccc(F)cc3)n2C)n(C)c1=O +COc1ccc2cc3cc(C(=O)N4CCN(C5CCCCC5)CC4)oc3nc2c1 +CC1CN(c2ccc(C(F)(F)F)c(-c3cnc(N)c(C(=O)Nc4ncccc4N4CCC(C)(N)CC4)n3)n2)CCO1 +CC(C)(NC(=O)OCc1ccccc1)C(=O)N1CCc2c([nH]c3cccc4c(=O)[nH]nc2c34)C1 +COC(=O)CNC(=O)C1(c2ccc(-c3ccc(CCN4CCCC4C)cc3)cc2)CCCC1 +CNCCN1CCC(c2cc(C)c3[nH]c(-c4ccc(F)cc4OC)nc3c2)CC1 +CCOCCCOc1ccc(S(=O)(=O)N2Cc3cc(O)c(O)cc3CC2C(=O)NO)cc1 +Cc1cc(NN=Cc2ccc(OC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)c2c(Cl)ccc(C)c2n1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CS(=O)(=O)C(c2ccccc2)c2ccccc2)CC1 +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2c(c1)NCC(CN1CCC(O)C1)O2 +COc1ccc(C=CC(=O)SSC(=O)C=Cc2ccc(OC)cc2)cc1 +O=C(Nc1ccc(CO)cc1)c1cnn2c(-c3ccccc3)ccnc12 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+CCOC(=O)Nc1cc2c(cn1)NC(c1ccccc1)C(C)N2 +O=C(Nc1ccc(-c2ccccc2)cc1)c1ccccc1Cn1ccc2ncnc-2c1 +COc1cc2ncnc(Oc3cc(NC(=O)Nc4cc(C(C)(C)C)on4)ccc3F)c2cc1OC +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(Br)cn1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCCOCC4)cc3OC)ncc2C(F)(F)F)c1 +O=c1c(N2CCC(O)CC2)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 +CN1C(=N)NC(C)(c2sc(-c3cccc(-c4nnco4)c3F)cc2Cl)CS1(=O)=O +Cc1c(C(=O)NCCN2CCN(c3cccc(Cl)c3Cl)CC2)cc(-c2ccccc2)n1C +Cn1c(=O)c2nc(C3CCCCC3)[nH]c2n(C)c1=O +COc1cc(OC)c(C(=O)C=Cc2cnccn2)c(OC)c1 +O=C(CCc1c(C(=O)O)[nH]c2ccccc12)Nc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 +O=C(C1CCCN(c2ccc3nc(C4(Cc5ccccc5)CC4)[nH]c3n2)C1)N1CCCC1 +O=C(Nc1cccc(CN2CCC(C(=O)NC(CO)C3CCCCC3)CC2)c1)c1cccc(C(F)(F)F)n1 +CN1C(=O)c2cccnc2N(C2CC2)c2cc(Cl)cnc21 +O=C1Nc2ccc(C(=O)CCl)cc2C1=Cc1cnc[nH]1 +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C12CN(Cc1cc(C(=O)O)cs1)CC2c1ccc(C#N)cc1 +O=C(Nc1cccnc1)c1cccc(Oc2ccc3c(c2)c(=O)ncn3Cc2c(F)cc(F)cc2F)c1C(F)(F)F +CC(C)c1noc(-c2ncn3c2CN(C)C(=O)c2c(Cl)cccc2-3)n1 +CCS(=O)(=O)c1ccc2c(c1)nc(C1CC1)n2CC1CCOCC1 +COCC1OC(O)(C(=O)C(=O)N2CCCCC2C(=O)OCC(C)=CC2CCC(O)C(OC)C2)C(C)CC1OC +Cc1ccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CCN(CC4CCOCC4)CC2C)C3(C)C)nc1 +N#Cc1ccc(Cn2cncc2COCc2ccc(C#N)cc2-c2cccc(OC(F)(F)F)c2)cc1 +O=C1C=C(N2CC2)C(=O)C(c2ccc(Oc3ccccc3)cc2)=C1N1CC1 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3C(=O)N(C)CCO)cc2)cs1 +CC(C)C(CC(O)C(N)CN1CC(=O)N(c2ccccc2Cl)CC1(C)C)C(=O)NC12CC3CC(CC(O)(C3)C1)C2 +COc1ccc(CCNc2cc(-c3cccc(S(N)(=O)=O)c3)nc(OC)n2)cc1 +CC1(C)CN(C(=O)Cn2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cc3c(Oc4cccnc4)ccnc32)C1 +N=C(N)c1cccc(-c2[nH]c(O)nc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +CCN(CCc1ccc(Cl)cc1)C1CCN(c2nc(N)n[nH]2)CC1 +CC(=O)c1ccc(-c2nccnc2OC2CC(Nc3nc4ccccc4s3)C2)cn1 +COc1cc(NS(=O)(=O)c2ccc(Cl)cc2)ccc1-c1cncnc1C +CSC(=S)N1CC2(CCCCC2)COC1=Nc1cc(C(C)(C)C)no1 +CNc1nc(Nc2cc(OC)c(C(=O)N3CCC(F)(F)CC3)cc2Cl)ncc1Cl +[H]C([H])([H])C(c1ccccc1-c1ncc(C)c(NCc2ccc(-n3ccnn3)cc2)n1)C([H])([H])[H] +CCOC(=O)c1cc2ccc(Oc3ccnc(C(=O)NC)c3)cc2s1 +Nc1ccc2c(Nc3ccc(CN4CCCCC4)cc3)c3ccc(N)cc3nc2c1 +FC(F)(F)Oc1cccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)c1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCN1CCS(=O)(=O)CC1 +O=S(=O)(c1cccc(C(F)(F)F)c1)c1cc(Cl)c2oc3c(c2c1)CNCC3 +Clc1ccc2[nH]c3c(c2c1)CCN(CCc1ccncc1)C3 +CCC(=O)N(CCCCCCCNC(=N)N)C1CCN(CCc2ccccc2)CC1 +COc1ccc(C2c3[nH]c4ccccc4c3CC3C(=O)N(C4CCCCC4)C(=O)N32)cc1 +Cc1ccc(N2CCN(C(=O)C(C)Cc3ccc(Cl)cc3)CC2)c(C(CC(C)C)NC(=O)CCN(C)C)c1 +CCOc1ccc(-n2c(C)c3c(C)nnc(NCc4cccc5cccnc45)c3c2C)cc1 +CN1CCCC(c2nc3ccccc3n2CCOc2ccccc2)C1 +Clc1ccc(-c2c[nH]c3ncc(-c4ccncc4)nc23)cn1 +CC(=O)c1ccc(-c2ccc(-c3csc(C(=O)NCCN4CCOCC4)c3)cc2)cc1 +O=C(NCC1CN(c2ccc3c(c2)OCc2nccn2-3)C(=O)O1)c1ccc(Cl)s1 +CCCCCCCCCCNC(=S)N1C(CO)C(O)C(O)C1CO +C=CCNc1nc(C#CCO)cn2c(-c3ccc(-c4cnc(C5CC5)[nH]4)cc3)cnc12 +COC(C)(C)CCn1nc(Nc2c(C)cccc2C)c2cnc(Nc3ccc(N4CCNCC4)cc3)nc21 +COC(=O)c1c(O)cccc1OCC=Cc1cccc(-c2onc(C(=O)O)c2CO)c1 +Cc1c(-c2cccc(O)c2)n(Cc2ccc(OCCN3CCCCC3)cc2)c2ccc(O)cc12 +COc1ccc2[nH]nc(-c3cc(N4CC5CCC(C4)O5)ncn3)c2c1 +COc1ccccc1N1CCN(CCn2c(=O)[nH]c3[nH]c(-c4ccccc4)cc3c2=O)CC1 +O=C(CN1CCC(C(=O)c2ccc(OCCC3CC3)cc2)CC1)NCc1nc2c(c(=O)[nH]1)COCC2 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cc2ccccc2[nH]1 +COc1cc(OC(C)c2ccccc2)ccc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +COc1cc2cc(-c3cc(F)c(OC)c(F)c3)cnc2cc1OC +O=S(=O)(c1ccccc1)c1cc(Nc2cc(-c3ccc(C(F)(F)F)cc3)[nH]n2)nc(NC2CCC(O)CC2)c1 +Cc1ccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)cc1 +O=c1[nH]c(N2CCC3(CCN(c4ccc(Cl)cc4)C3)C2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +Cc1cc(NC(=O)C(=O)c2cn(Cc3ccno3)c3ccccc23)sn1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])C(=O)Nc1cccc(Cl)c1 +O=C(NCCCCN1CCCC1)C1C(C(=O)NCc2c(F)cc(F)cc2F)C2C=CC1C21CC1 +CCCc1c(CCN(C)C)c2cc(OC)ccc2n1S(=O)(=O)c1ccccc1 +Cc1cccc2cc(C(C)Nc3nc(N)ncc3F)n(-c3ccccc3)c(=O)c12 +CC(=O)NCCNS(=O)(=O)c1ccc(-c2sc(NC(C)=O)nc2C)o1 +CCN(CC)c1ccc(C(NC(=O)C=Cc2ccccc2)NC(=O)C=Cc2ccccc2)cc1 +O=C(OCC1C2CC3CCC1N3CC2=Cc1cccs1)c1ccc2ccccc2c1 +COc1ccccc1N1CCN(CC=CCNC(=O)c2cc3ccccc3o2)CC1 +O=C1NC(=O)c2ccc(-c3ccc(O)cc3)cc2C1=CNc1ccc(CN2CCCCC2)cc1 +CN(C(=O)c1cc(-c2ccccn2)n[nH]1)c1ccc(OCc2ccc3ccccc3n2)cc1 +O=c1n(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)nc2ccc(C(F)(F)F)cn12 +NC(=O)Nc1ccc(-c2cccc3onc(N)c23)cc1 +O=C(O)C1=C(NC(=O)C2(Cc3nc(-c4ccc(O)cn4)no3)CCC2)CCCC1 +Cc1nc2c([N+](=O)[O-])c(Cl)c(Cl)cc2n1Cc1ccc(-n2cccc2)cc1 +COc1cc(-c2ccc(Cl)cc2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ncc(F)cn3)ccc21 +Cc1cccc(N2CCN(CC(O)CNC(=O)c3nc(C(C)C)n(-c4ccccc4)c3C)CC2)c1C +CN(C)c1ccc(-c2cc(-c3ccc(N)cc3)[se+]c(-c3ccc(N)cc3)c2)cc1 +COCCOc1c(OC)cc2c(N)nc(N3CCN(C(=O)C=Cc4ccc(C#N)cc4)CC3)nc2c1F +NC1(c2ccc(-c3nc4nc(O)ccn4c3-c3ccccc3)cc2)CCC1 +Cn1cnc2c(C#N)nc(-c3ccc(OCc4ccccn4)c(C(F)(F)F)c3)cc21 +CN1CC(C(NC(=O)c2ccc3cnccc3c2)c2ccc(Cl)c(Cl)c2)C1 +CCOC(=O)c1ncn2c1CN(Cc1ccccc1)C(=O)c1c(Cl)cccc1-2 +O=C(NC(CS(=O)(=O)c1ccc(Sc2ccccc2)cc1)C(=O)NO)OCc1ccccc1 +CNC(=O)C(NC(=O)C(Sc1ccccc1F)C(O)C(O)C(Sc1ccccc1F)C(=O)NC(C(=O)NC)C(C)C)C(C)C +c1ccc(CN2CCN(CCCNCc3cccnc3)CC2)cc1 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCCC2CCOC2)cc1F +COc1ccc2c(CC(=O)O)nn(Cc3nc4ccccc4s3)c(=O)c2c1 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+CC(C)CN(NC(=O)c1cccc(-c2ccccc2)c1)c1nc(C#N)ncc1Br +N#Cc1c[nH]c(C(=O)Nc2ccc(C3(O)CCOCC3)cc2C2=CCCCC2)n1 +CC(=O)OC1(C)CCC2CC1OOC2(CS(=O)(=O)c1ccccc1)c1ccccc1 +O=c1[nH]c2ccccc2c2c(=O)n(-c3ccc(Cl)cc3)[nH]c12 +COc1ccccc1N1CCN(CCCC(=O)c2cccc3c(=O)c(C)c(-c4ccccc4)oc23)CC1 +Cc1cc(Cl)ccc1NC(=S)NNC(=S)Nc1ccc(F)cc1 +CNc1ncc2cc(-c3cc(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4C)ccc3C)ccc2n1 +COCCCCN1CCN(c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)C1=O +Nc1cccc(-c2nc(N3CCOCC3)c3cnn(-c4ccccc4)c3n2)n1 +Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(-n4nccn4)cc32)cn1 +O=C(C1CC1)N1CCN(C(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Cc1nn(Cc2ccc(-c3nc4ccncc4[nH]3)cc2F)c(C)c1CC(=O)O +CC(=O)NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCCc2cccc3ccccc23)C1=O +CCN(CC)CCn1nc2c3c(c(NCCNCCO)ccc31)C(=O)c1c(O)ccc(O)c1-2 +Cc1ccc(-c2ccc(C(=O)O)c(NS(=O)(=O)c3ccc(C(=O)N(C)C)cc3)c2)c2ccccc12 +Cc1cc(S(=O)(=O)NC(=N)NNc2ccc(S(N)(=O)=O)cc2)c(SCc2cc3c(cc2Cl)OCO3)cc1Cl +NC(N)=NC(=O)c1ccc2c(Cl)cnc(-c3c(F)cccc3F)c2c1 +COc1ccc(Cc2cc(C3OC(SO)C(O)C(O)C3O)c3c(c2Cl)CCCO3)cc1 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+Cc1nnc(CNC(=O)C(c2nc3cc(C)c(-c4ccccc4)cc3s2)S(C)(=O)=O)o1 +COc1cc(OC)cc(N(CC#Cc2ncccc2OC)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +NC(=O)Nc1cc(-c2ccnn2-c2ccc(F)cc2Cl)ccn1 +N#Cc1c(Cl)cccc1OCC(O)CN1CCCC1Cc1ccccc1O +Cc1nc(NCCO)cc(Nc2ncc(C(=O)Nc3c(C)cccc3Cl)s2)n1 +CS(=O)(=O)N1CCc2c(c(-c3ccc(Cl)c(C#Cc4cccs4)c3)nn2CCCN2CCOCC2)C1 +O=S(=O)(NCC1CC1)c1ccc(NN2CCCCC2)cc1C(F)(F)F +COC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2 +CN(C)c1cc[n+](CCCCCCCCCCCC[n+]2ccc(-n3cnc4cncnc43)cc2)cc1 +COCCNCc1ccc(C=Cc2cncc(C#N)c2Nc2ccc3[nH]ccc3c2C)nc1 +O=C1Cc2c([nH]c3ccccc23)-c2cc(I)ccc2N1 +CC#CCOc1cnc(C(=O)Nc2cccc(CNc3cccnc3N)c2)cn1 +CC1(C)CC(=O)c2ccc(OCc3cccc(Cl)c3)cc2O1 +Cc1cnc(Cl)nc1-c1ccc(N(Cc2ccc(CNC(=O)c3cccs3)cc2)C(=O)c2ccc(O)cc2O)cc1 +COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(Br)cc4)c(C)c3)c2cc1OC +O=C(OCCO)c1[nH]c2ccc(Cl)cc2c1C1(c2ccccc2)CC1 +COc1ccc2c(c1)C(=Cc1c[nH]cn1)C(=O)N2 +COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3cccc(C)c3)c2cc1OC +COc1ccc(CN2C(=O)CNC(c3ccccc3)(C(Oc3nc(C)cc(C)n3)C(=O)O)c3ccccc32)cc1 +O=C1NC(=O)C(Cc2ccc(N3CCC(NCC(O)c4cccc(Cl)c4)CC3)cc2)S1 +O=c1cc(C=Cc2ccc(O)c(O)c2)oc2cc(O)ccc12 +N#Cc1ccc(S(=O)(=O)N(Cc2ccc(-c3nnn[nH]3)cc2)Cc2ccccn2)cc1 +Cc1nc2c(s1)C(=O)C=C(Nc1ccc(Br)cc1)C2=O +CC1(C)CCC(C)(C)c2cc3c(cc21)OC1CCCCCC31c1ccc(C(=O)O)cc1 +CC(C)C(CC=C1CC(CO)(COC(=O)c2ccccc2O)OC1=O)C(C)C +Cc1c(CNCC(C)C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1CCCc2ccc(CC(C)C)cc21 +COc1ccc(-n2nnc(-c3ccccc3NC(=O)Nc3ccc([N+](=O)[O-])cc3)n2)cc1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(OCCC4CC4)cc3)C2)cc1 +CCC1(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CCNCC1 +CSc1sc(C(=N)N)cc1-c1nc(-c2ccc(Cl)c([N+](=O)[O-])c2)cs1 +O=C(O)CCc1ccc(OCCN(Cc2ccc(C(F)(F)F)cc2)c2nc3ccccc3s2)cc1 +Nc1nc2c(cnn2CCc2ccc(O)cc2)c2nc(-c3ccco3)nn12 +CC(C)CC1CC(C(O)CC(=O)Cc2ccccc2)C(=O)N1 +CC(C)(C)c1cc2cc[nH]c2cc1NC(=O)c1c[nH]c2ccccc2c1=O +CCCC[S+]([O-])c1cc2c(-c3ccccc3)nc(-c3ccccc3)nc2s1 +O=C(Nc1cccc(O)c1)c1ccc(OCCCN2CCCC2)cc1OCc1cccnc1 +NC1CCCCC1NC(=O)c1c2c(c3c4c(ncnc14)-c1ccccc1C3=O)NC1CCCCC1N2 +OC(CNCc1ccccc1OCCN1CCOCC1)c1cc(Br)cs1 +O=C(O)CCC(=O)Nc1nc2ccc(NC(=O)c3cc(Br)c(Br)[nH]3)cc2s1 +Cc1oc2c(c1CC(=O)Nc1nc(-c3cccc(C(F)(F)F)c3F)cs1)c(=O)n(C)c(=O)n2C +N#CC1CCCN1C(=O)CNC1CC2CC(OC(=O)Nc3ccccc3)CC2C1 +COc1cc(OC(C)c2ccncc2)c(F)cc1C(=O)N1CCC(N2C(=O)OCc3ccccc32)CC1 +NC(=O)C1CCCN(C(=O)c2cc(-c3ccc4[nH]ncc4c3)on2)C1 +CC(C)Oc1cc2c(-c3cc(N4CCN(C(=O)C5CC5)CC4)ncn3)n[nH]c2cc1F +CN1C2CCC1C(c1ncc(-c3ccccc3)o1)C(c1ccc(Cl)cc1)C2 +CC(c1ccc(F)cc1)N1C(=O)OC(Cc2ccccc2)(c2nc3cc(Cl)ccc3[nH]2)C1=O +O=C(NCC1CC1c1cccc2oc(CCCCc3ccccc3)cc12)C1CC1 +CN1CCN(Cc2ccc(NC(=O)CNc3ccc(-c4ccc(NC(=O)C5CC5)nc4)cc3F)cc2C(F)(F)F)CC1 +CN(CCCNc1ncnc2oc(-c3ccccc3)nc12)c1ccccc1 +FC(F)(F)c1cc(COCc2ccccc2-c2ccccc2)cc(C(F)(F)F)c1 +N#CC(C(=O)Nc1ccc(C(F)(F)F)cc1)=C(O)C1CC1 +Nc1ncnc2c1ncn2C1CCC(OCP(=O)(O)OP(=O)(O)OP(=O)(O)O)O1 +Cc1ccc(Cl)cc1NC(=O)CCCNC(=O)C(C)c1ccc(CC(C)C)cc1 +CC1CCc2cc(C(=O)N(C)Cc3ccnc(Cl)c3)ccc2N1C(=O)c1ccc(O)cc1O +Cc1ccc(Nc2ncnc3sc(NC(=O)CCCCCC(=O)NO)cc23)cc1C +COc1ccc(-c2cc3nc(Br)ccc3c(NCCCN)n2)cc1 +Cn1ncc(C(=O)N2CCC2)c1C(=O)Nc1ccc2nc(-c3cccnc3)nn2c1 +Cc1nc(N)ncc1CNC(=O)Cn1c(C)cnc(NCCc2ccc3c(c2)CCO3)c1=O +CCOC(=O)c1ccccc1NC(=O)Cn1c(-c2nonc2N)nc2ccccc21 +COc1ccc(F)c(-c2ccc3c(NC(=O)c4ccc(N5CC(C)NC(C)C5)cc4)n[nH]c3c2)c1F +O=C1Nc2ccccc2C1=C1Nc2ccccc2C1=NOCCOC1OC(CO)C(O)C(O)C1O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccc(OC)cc1c2C1CCCC1 +CN1CC(n2nccc2-c2cc(F)ccc2Oc2cc(F)c(S(=O)(=O)Nc3cscn3)cc2Cl)C1 +N#Cc1c(N2CCC(c3ccccc3)CC2)ccn(CC2CC2)c1=O +COc1cccc(OC)c1C1COC(=O)N1Cc1ccc(OC(F)(F)F)cc1 +CCC(=O)CCCCCC(NC(=O)C12CCN(CC1)CC2)c1ncc(-c2ccc3ccccc3c2)[nH]1 +O=C(O)CC(NC(=O)Cn1cc(CCCNc2ccccn2)nn1)c1ccc(O)cc1 +CC(=O)c1ccc(N2CCC(OC(=O)N3CCN(C4CCC4)CC3)CC2)nc1 +CCOc1ccc(NC(=O)c2cccc(-n3ncc4cc(Nc5ccccc5F)ccc43)c2)cc1OC +CCC1(C)OC(=O)C(OC(C)C)=C1c1ccc(S(C)(=O)=O)cc1 +CCCNC(=O)C(NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)c(C)c1)c1ccccc1 +CC1CC(N)CN(c2ccncc2Nc2ncc3ccc(-c4ncccc4Cl)nn23)C1 +COc1ccc(S(=O)(=O)N(Cc2cccnc2)c2c(C)cc(Br)cc2C(=O)NO)cc1 +O=C1C(=C(O)c2ccccc2)C(=O)N(c2ccc(Cl)cc2)N1c1ccc(Cl)cc1 +COc1cc(CCN(C)C)c2sc3c(O)c(OC)cc(CCN(C)C)c3ssc2c1O +O=c1c2cn[nH]c2c2ccc(-c3cccc(N4CCOCC4)n3)cc2n1CC(F)(F)F +O=C(O)c1cc2cc(OCc3c(Cl)cccc3Cl)ccc2n1Cc1ccc(O)cc1 +[C-]#[N+]c1ccc(Oc2ccc(-c3nc(C(N)=O)cc(C(O)CO)n3)cc2)cc1C(F)(F)F +O=C(CN1CCC(C(=O)c2ccc(Cl)cc2)CC1)NCc1nc2c(c(=O)[nH]1)COCC2 +COc1ccc2nc(C)c3c(C)nc(-c4c(C)nn(C)c4C)n3c2n1 +ON=c1cc(-c2cc3cccn3cn2)oc2ccc(OCCN3CCOCC3)cc12 +CN1CCC(Cn2c(CN(C)C3CCCc4cccnc43)nc3ccccc32)C1 +CCC1CCN(c2c(F)cc3c(=O)n(N)c(=O)n(C4CC4)c3c2C)C1 +CC(C=CC1CC2(CO2)CC(C)(C)O1)=CCC1CCC(NC(=O)C=CC(C)OC(=O)C(F)(F)F)CC1 +COc1ccc(C2OC(CO)C(O)C(O)C2O)cc1Cc1cc2cccccc-2c1 +O=C(NCc1ccc(F)cc1)c1c(O)c2ncc(Cc3ccccc3)cc2n(CCN2CCCC2=O)c1=O +CCCCCCN(C)CNCC(=O)C(CC(=O)O)NC(=O)C(CC)n1cc(CC)nc(NCc2nonc2C)c1=O +COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2C)N(c2cc(Cl)ccc2C)C3=O)c(OC)n1 +Cc1c(Cl)cccc1S(=O)(=O)NCC(C)(C)C(=O)NC1C2CC3CC1CC(C(N)=O)(C3)C2 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCOc3ccc(F)cc3)c2)c1 +NC1CCCCC=CCC(C(=O)NCc2ccccc2CC(=O)O)NC(=O)C(Cc2ccc(O)cc2)NC1=O +Cc1cc(-c2nnc(N)nc2-c2ccccc2)cc(C(F)(F)F)n1 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCOc3cc(F)ccc31)CC2 +CCS(=O)(=O)c1cccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)c1 +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)Nc1ccc(NC(=O)c2cscn2)cc1 +Fc1cccc(F)c1Cn1c(-c2c(F)cccc2F)nc2c(CCl)cccc21 +Cc1cccc(C)c1Nc1nc2cccc([N+](=O)[O-])c2n2cncc12 +CCCCCn1cc(CC(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(Br)ccc21 +Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)c(Cl)c1 +NCC1CCCN1C(=O)C1CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +NC1=NC2(CCOCC2)N(OCCCOc2cc(Cl)c(Cl)cc2Cl)C(N)=N1 +CNC(C)C(=O)NC(C(=O)N1CCC2CCC(NC(=O)c3ccc4ccccc4c3)C21)C(C)(C)C +O=C(O)c1ccc(Nc2ncc(F)c(Nc3ccccc3C(=O)O)n2)cc1 +CN1CC2(CNC(=O)c3c2[nH]c2c3CCc3cnc(-c4cccc(F)c4)nc3-2)C1 +O=S(=O)(Nc1nc(NCCc2ccccc2)nc2c1CN(Cc1ccccc1)CC2)c1ccc(Cl)c(Cl)c1 +Nc1ncc(-c2cc(N3C4CCC3COC4)nc(N3CC4CC3C4)n2)cn1 +COc1ccc(NCCC2(c3ccccc3)CCOC(C)(C)C2)cc1OC +O=C(NO)C1Cc2ccccc2CN1S(=O)(=O)c1ccc2oc3ccccc3c2c1 +O=C(Nc1nc2ccc(C(=O)N3CCC(NCc4ccc5ccccc5c4)CC3)cc2s1)C1CCCCC1 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+O=Cc1ccc(C2=CCC(N(CCN3CCCC3)C(=O)Nc3ccc(F)c(Cl)c3)CC2)o1 +N#Cc1cc(-c2nc(-c3ccc4c(c3)CCN4C(=O)CCC(=O)O)no2)ccc1OC1CCCC1 +Oc1cc(Nc2nccc(-c3nccs3)n2)cc(C(F)(F)F)c1 +N#Cc1cc2c(O)c(-c3ccccc3)c(O)nc2cc1Cl +Cc1ccc(C(=O)Nc2cccc(NC(=O)C(C)N)n2)nc1 +O=C(Nc1nccc2nc(-c3c(F)cccc3Cl)sc12)NC1CC1 +COc1cc(OC)cc(N(CCCN2CCC(F)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CNC(CC(C)C)C(=O)NC1CCC2CN(S(=O)(=O)c3cccc(C(F)(F)F)c3)CC21 +CCC(CC)(c1ccc(O)c(C)c1)c1ccc(O)c(C)c1 +CC(C)(N)C(=O)NC(CCC(F)(F)c1ccccc1)c1nnnn1CCOC(=O)NCCCCO +Cc1ccc(C2CC2COc2nc(C)ncc2-c2ccn(CC(F)F)c(=O)c2)nc1 +O=C(Nc1ccc(C2=CCN(CC3CCOC3)CC2)cc1)N1Cc2ccncc2C1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncnc2c1ncn2CC(=O)O +Cc1cc(NC(=O)Nc2ccc(F)c(C(F)(F)F)c2)ccc1Oc1cc(NC(=O)C2CC2)ncn1 +CC(Oc1nc(C(=O)N(C)C(C)(C)C)ccc1C1CC1)C(F)(F)F +NC(=O)c1ccccc1Nc1nc(Nc2ccc(N3CCCC3=O)cc2)ncc1Cl +Cc1nc(N2CCN(C)CC2)cc(-c2ccccc2)c1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1ccc(-c2cc(C(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)cc1C +Fc1ccccc1N1CCN(Cc2cn(-c3ccccc3)c(-c3ccccc3)n2)CC1 +O=C(c1ccc(-c2ccc(F)cc2F)s1)c1c(F)ccc(O)c1F +CCCCNC(=O)CC(O)C(COCc1ccc(-c2ccccc2)cc1)NC(=O)C(NC(=O)c1ccccn1)C(C)C +COc1cc(S(=O)(=O)N2CCOCC2)ccc1NC(=O)COC(=O)c1ccccn1 +Cc1nc(-c2nnc3n2CCN(C(=O)c2ccc(F)cc2)C3C)cs1 +CCOCN1C2=C(C(=O)Nc3ccc(OC)cc3F)C(=O)CCN2c2ccc(F)cc21 +COc1cc(C=CC(=O)N2CCC(n3c(O)nc4ccccc43)CC2)c([N+](=O)[O-])cc1OC +COc1cc2c(cn1)C(Oc1ccc(Cn3c(N)nc4cc(-c5cnn(C)c5)cnc43)cc1OC)CCC2 +CC1=C2CCc3cc(-c4ccccc4)ccc3N2CCC1=O +CN(C(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21)c1ccccc1 +Cc1ccc(C)c(S(=O)(=O)N(C)N=Cc2cnn3ccc(C#N)cc23)c1 +Cc1cccc(Nc2ccccc2C(=O)NCCCCCCCNc2c3c(nc4cc(Cl)ccc24)CCCC3)c1C +CCCCC(NC(=O)OCC1(COc2nc(-c3ccccc3)cs2)CCC1)C(=O)C(=O)NC(C)c1ccccc1 +Cc1c2c(=O)n(-c3ccccc3Cl)[nH]c2cc(=O)n1Cc1ccc(CN2CCN(C)CC2)cc1 +COc1ccc2c(c1)c1cc(C(=O)NCCN(C)C)c3ncccc3c1n2C +COc1cc(Nc2ncc(F)c(Nc3ccc4c(n3)NC(=O)C(C)(C)O4)n2)cc(OC)c1OC +Cn1nc(CC(CC(=O)O)c2cnc(-c3ccc(Cl)cc3)s2)cc1OCCc1ccc2c(n1)NCCC2 +O=C(c1ccc(Cl)cc1)N(CC1CC1)c1nnc(-c2cccc(F)c2)s1 +Cc1cnc(N2CCN(C(=O)C3CCS(=O)(=O)CC3)C(c3ccccc3F)C2)nc1 +O=c1ccn2c(-c3ccc(F)cc3F)cccc2c1-c1cc(-c2nnco2)ccc1F +CCc1ncnc(-c2ccc(C(=O)N3CCN(C4CCOCC4)CC3)c(OC)c2)c1C#Cc1ccc(N)nc1 +O=C(Nc1ccc2nc(C3CC3)c(C3CC3)n2c1)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 +COc1cccc(COc2c(C(C)=O)c(O)c(OC)c3occc23)c1 +CC(Nc1nc(Nc2cn(C)cn2)c2cccnc2n1)c1ncc(F)cn1 +NS(=O)(=O)c1ccc(-n2nc(COCc3ccccc3)cc2-c2ccc(Cl)cc2)cc1 +COP(=O)(O)OP(=O)(O)OCC1OC(n2ccc(=O)[nH]c2=S)C(O)C1O +CC(C)NC(=O)c1c[nH]c2ncc(Oc3ccc4c(c3)CCC4)nc12 +CSc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4[nH]c(=O)cnc34)c3ccccc23)cc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(-n4cnc(CCNC(C)=O)c4)cc3)NC(=O)NC1=O)C2 +N#CCc1ccc(Nc2ncnc3ccc(-c4cccc(O)c4)cc23)cc1 +CCOc1ccc(C)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 +CC1CCCN1CCc1cc2cc(C(=O)c3ccccc3)ccc2o1 +c1ccc(-c2ccc3ncnc(Nc4cccc5[nH]ncc45)c3c2)cc1 +O=C(CCCCCCCOc1ccc(-c2nc(N3CCOCC3)c3sccc3n2)cc1)NO +O=C(C=Cc1ccc2[nH]c(C(=O)c3ccccc3)cc2c1)NO +O=C1CCOc2c(OCCNCCCCc3ccc(O)cc3)cc(F)cc21 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(Oc2cccc(Cl)c2C#N)cc1 +O=C(NCCN1CCOCC1)c1cc(-n2ncc3cc(Nc4c(Cl)cccc4Cl)ccc32)ccn1 +CCCCc1ccc(N2CCN(CCn3c(=O)[nH]c4c([nH]c5ccccc54)c3=O)CC2)cc1 +O=C(C=NNc1ccc([N+](=O)[O-])cc1[N+](=O)[O-])NCCCCCCCNc1ccnc2cc(Cl)ccc12 +CCC(O)(CC)C1CC(Nc2nc(NCCOC)nc(C)c2-c2nc3c(C)nccc3s2)C(O)C1O +CCCCn1cc(CCCOc2ccc(C(=O)NCCCN3CCCN(c4ccc(O)c5[nH]c(=O)ccc45)CC3)cc2OC)nn1 +COc1ccc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cnc2NCCCO)cn1 +COc1ccc(C2=NOC(C(=O)NCc3cccs3)C2)cc1OC +CCCCC(=O)c1cccc2c(C)c(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)sc12 +Cc1cc[n+]([O-])c(C)c1C(=O)N1CCC(C)(N2CCN(C(C)c3ccc(C(F)(F)F)cc3)C(C)C2)CC1 +Cc1c(-c2ccccc2Cl)cc(F)c(Nc2ncccc2C(=O)O)c1F +NC(=O)c1ccc2c(c1)CCOC2CCN1CC=C(c2cccc3ccccc23)CC1 +COc1cccc2c1c(NS(=O)(=O)c1ccc(Cl)s1)nn2Cc1cccc(CN(C)C(C)=O)c1 +O=C(O)c1ccc(Nc2ncc(-c3ccncc3)c(Nc3ccccc3)n2)cc1 +COc1cc2nc(N3CCN(C)CC3)cc(NC3CCN(Cc4ccccc4)CC3)c2cc1OC +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(n1cc(CCC(=O)OCc3ccc(F)cc3)nn1)CC2 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NCC3CCCCC3)CC2)c(C)c1 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+CC1CCCC(N2CCC(c3c(F)ccc(Cl)c3F)=CC2=O)c2cc(ccn2)-c2ccc(Nc3ccccn3)cc2NC1=O +Cc1ncccc1N1CCC(Cc2ccc3oc(-c4cc5sccc5cn4)cc(=NO)c3c2)CC1 +O=C(NCCF)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(C4CCC5(CC4)OCCO5)c3n2)cc1 +CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)on2)CC1 +COc1cc2cc3c(Nc4cc(OC)c(OC)c(OC)c4)c(C#N)cnc3cc2cc1OCCN1CCOCC1 +Clc1ccc(CNc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)cc1 +OC(CCc1ccccc1)CN1CCC(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +CC(C)CC(C(=O)NC(Cc1ccccc1)C(=O)c1c[nH]c2ccccc12)C(O)C(=O)NO +O=S1(=O)C(c2ccccc2)CCCCN1Cc1cc(F)c(N2CC3C(C2)C3n2cnnc2)cc1F +COc1cc(C(=O)NC(=S)Nc2ccc(C)c(NC(=O)c3cccc(-c4ccccc4)c3)c2)cc(OC)c1OC +CCc1nnc2n1-c1ccc(C#CCN3C(=O)c4ccccc4C3=O)cc1C(c1ccccc1F)=NC2 +CS(=O)(=O)c1ccc(-c2[nH]c3ccc(F)cc3c2-c2ccccc2)cc1 +CS(=O)(=O)c1cccc(-c2nc(C(c3ccc(F)cc3)c3ccc(F)cc3)sc2CC(=O)O)c1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C(N)=O +O=C(NCC(Cc1ccccc1)N1CCC(C(F)(F)F)CC1)C1(c2ccc(Cl)cc2)CCCC1 +CN(C(=O)C=CCC(C)(C)N)C(Cc1ccc2ccccc2c1)C(=O)N(C)C(Cc1ccccc1)C(=O)NCC1CC1 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+O=C(c1n[nH]c2c1CN(CC(F)(F)F)CC2)N1CCC(c2cccc(F)c2C(F)(F)F)CC1 +NS(=O)(=O)c1ccc(CNS(=O)(=O)C2OC(C(=O)O)C(O)C(O)C2O)cc1 +NC(=O)CNC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc3c(c2)OC(OC)O3)cc1 +CCCCc1nc(Cl)c(CO)n1Cc1ccc(-c2cccnc2C(=O)O)cc1 +CCCC(Oc1ccc(-n2cc3cc(F)ccc3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 +Nc1ccc(Cl)cc1C(=O)NC1CCN(Cc2ccc3c(c2)OCO3)CC1 +O=C(NCc1cc(Br)cc2nc(O)c(O)nc12)c1ccco1 +O=CN(O)C(CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1)c1ccccc1 +CC(=NNc1ccc(S(N)(=O)=O)cc1)c1cc2cc(Cl)ccc2oc1=O +CC(C)CC(NC(=O)C(Cc1c[nH]c2ccccc12)NS(C)(=O)=O)B(O)O +c1ccc(-c2cnc3nc(N4CCN5CCC4CC5)oc3c2)cc1 +N#CC(C#N)=C1N(CCCCN2CCCCC2)CCN1CCN1CCCCC1 +Cc1cccc(C)c1Oc1ccc(C#N)c(C(F)(F)F)c1 +O=C(O)CNC(=O)c1c(O)cc(-c2cc(F)cc(Cl)c2)c2ncnn12 +NC(=NCc1ccccc1)Nc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +Nc1nc(NCC2CCCN2Cc2cc3ccccc3o2)nc2nc(-c3ccco3)nn12 +OCC1OC(c2cc(Cc3ccc(C4CCCC4)cc3)c(Cl)c3c2CCO3)C(O)C(O)C1O +O=C(NCCCCc1ccc(Cl)c(Cl)c1)c1ccccc1CNCCc1ccc(O)cc1 +CC(C)(NC(=O)C(NC(=O)C(CCCc1ccccc1)CC(=O)O)C(C)(C)C)c1ccccc1 +COC(=O)c1ccc(NC(=O)c2cccc(-c3cn4ccnc4c(Nc4ccc(OC)c(OC)c4)n3)c2)cc1 +COC1CCC2(CCc3ccc(Br)cc3C23N=C(C)C(N)=N3)CC1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc([N+](=O)[O-])cc4)cc3F)ccnc2cc1OCCCN1CCCC1 +CC(=O)N(CC(CC(C)C)N1CCN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2F)CC1)C(C)C +Cc1ccc(C=C2SC(=S)N(CCCC(=O)NNC(=O)c3ccccc3O)C2=O)cc1 +CN1CCCC1Cc1c[nH]c2ccc(C3=CCN(C(S)=NC45CC6CC(CC(C6)C4)C5)CC3)cc12 +CC(C)c1cccc(C(C)C)c1N(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC1CCCCC1 +COc1cccc(C#Cc2c(-c3ccccc3)oc3cc(O)c(C(=O)O)cc23)c1 +Cc1ccc(F)cc1Oc1c(C(=O)N2CCNCC2)c2ccccc2n1C1C=CCCC1 +Cn1c(NCCN(CCO)CCCc2ccc([N+](=O)[O-])cc2)cc(=O)n(C)c1=O +COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCC1CCNCC1 +C=CC1(C)CC(=O)C2(O)C(C)(O1)C(OC(C)=O)C(O)C1C(C)(C)CCC(O)C12C +CC(=O)c1cccc(OCc2ccc(C(F)(F)F)cc2)c1 +CN1C(=O)c2[nH]c(Cc3ccccc3)nc2N2CC(Cc3ccccc3)N=C12 +COc1cc(Nc2cccc3c2nc(Cc2ccc(F)cc2)n3C)ccc1-n1cnc(C)c1 +CCN(CC)S(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc([N+](=O)[O-])s2)c1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(OC2C3CC4CC(C3)CC2C4)cc1F +O=C(NCCCCNc1ccnc2cc(Cl)ccc12)c1cccc(Br)c1 +CC(C)(C)c1cc(F)c2c(=O)n(-c3cccc(-n4cc(C(N)=O)cn4)c3CO)ncc2c1 +O=C(Nc1ccccc1C(=O)O)c1cc(O)c(Br)c(Oc2ccccc2)c1 +CCN(C(=O)OCCCO[N+](=O)[O-])C1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +Cc1ccc2c(c1)sc1nc(-c3ccc(Br)cc3)cn12 +CCOc1ccc(Nc2nc(=O)n(CC(C)C(=O)OC)c(=O)n2Cc2ccc(Cl)cc2)cc1C +CCN1CCC(N2CCC(c3cc(NC(=O)c4cnn5cccnc45)n(-c4ccc(C)cn4)n3)CC2)CC1 +CC(C)(C)C(NC(=O)C(CC1CCCC1)CN(O)C=O)C(=O)c1ccc(N2CCN(CCO)CC2)c(F)c1 +CC(C)Oc1nccc2[nH]nc(-c3cc(C(=O)N4CCOCC4)n(C(C)C)c3)c12 +CC1CCN(S(=O)(=O)c2cccc(-c3ccccc3)n2)CC1 +CCOC(=O)c1nc(-c2ccc(NC(=O)Nc3ccc(NS(C)(=O)=O)cc3)cc2)nc(N2CCOCC2)c1OCC +CC(C)(NC(=O)CCNCC(=O)N1CCCC1C#N)c1ccccc1 +COc1ccc(Br)cc1CCc1c(Cl)cccc1C1=NCCN1 +CS(=O)(=O)c1ccc(S(=O)(=O)n2c(C3(O)C=CC(=O)C=C3)cc3ccccc32)cc1 +CCCN(c1nc(-c2ccc(OC)cc2C)n(C)n1)C(CC)c1ccc(C(F)(F)F)cc1 +OC1C(O)C(n2cnc3c(NC4CC4c4ccccc4)nc(Cl)nc32)C2CC12 +CC1CN(c2noc(C(C)(C)O)n2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)nc31)CNCC2 +COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cccnc3n(CCC(C)C)c1=O)N2 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)c3cccnc3)c2cn1)c1ccccc1 +Cc1cc(C(=O)NCC[N+]2(C)CCCCC2)cc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +CCNCc1cncc(-c2cnc3c(c2)C(c2nc4cc(F)ccc4[nH]2)N=N3)c1 +O=S(=O)(c1ccc(-c2nnn[nH]2)cc1)N(CCC1CC1)c1cc2ccccc2s1 +COCCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NC4CC4)ccc3C)c2c1C +CN1CCN(c2ccc(-c3cnc4[nH]c5cnc(C(N)=O)cc5c4c3)cc2)CC1 +CCNC(=O)c1noc(-c2cc(Cl)c(O)cc2O)c1NC(=O)c1ccc(OC)cc1 +COc1ccc(OCCCOc2ccc3c(c2)CCC3CC(=O)O)cc1 +O=S(=O)(Nc1nncs1)c1ccc(Oc2ccc(OC(F)(F)F)cc2-c2ccnnc2)c(Cl)c1 +CN1CC(NC(=O)c2c(C(N)=O)nc3n2CCOc2cc(F)c(C#CC(C)(C)O)cc2-3)C1 +OCCN(CCO)c1c(Br)cccc1Nc1ncnc2ccncc12 +Cc1nn(Cc2c(Cl)cccc2Cl)c2cc(C(=O)CCC(=O)O)ccc12 +COc1cccc2nc(C=Cc3nc4c(C)ncc(C)n4n3)ccc12 +O=C(C=Cc1ccc2c(c1)nc(-c1ccccn1)n2CCCO)NO +CC(C)(C)c1ccc2c(c1)C(=O)c1ccc(C3=NCCN3)cc1S2(=O)=O +O=c1n(Cc2ccc(F)c(F)c2)ccn1-c1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cc1 +COC(=O)C(NC(=O)NC(C(=O)NC1CCCCNC(=O)C=CC(Cc2ccccc2F)NC1=O)C(C)C)C(C)C +NC(CCC(=O)NC(CSC(C(=O)O)c1ccccc1)C(=O)NCC(=O)O)C(=O)O +c1ccc(C2CCN(Cc3ccn(-c4ccccc4)c3)CC2)cc1 +COC(=O)N(CC(=O)O)Cc1cccc(OCc2csc(-c3ccc(Cl)cc3)n2)c1 +O=c1c2ccccc2nc(C(F)(F)F)n1-c1ccccc1 +CN(C)C(=O)c1cnc(-c2ccc3c(c2)Oc2ccccc2C3C(C)(C)C(=O)Nc2nncs2)nc1 +NC(=O)c1cccc2c(NC(CCN3CCCC3)c3cccc(NC(=O)c4ccc(F)cc4F)c3)ncnc12 +NC(=O)c1cc(F)cc2[nH]c(-c3ccc(-c4ccc(NC(=O)C5CC5)cc4F)cc3F)nc12 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)nc(OCCO)n1 +CCCC(=O)NCC1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +COc1cccc(Cn2c3cc(C)sc3c3cnn(C)c(=O)c32)c1 +CCn1nc(-c2cnccc2C)c2ncc(OCc3ccccn3)nc21 +COc1c(Cl)cccc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 +Fc1ccc(-c2ccc3ncc(-c4ccncc4)n3n2)cc1F +O=C(Nc1ccc(O)cc1)c1c(N2CCCCC2)cc(-c2ccccc2)oc1=O +CCOc1cccc(-c2c[nH]c3ccc(-c4nnc(NC)s4)cc23)n1 +COc1ccc(OC)c(S(=O)(=O)N2CCC(N3C(=O)OCc4cccc(C)c43)CC2)c1 +O=C(CN1CCOCC1)NC1CCCC(Nc2nc(-c3c[nH]c4ncc(Cl)cc34)ncc2F)C1 +OCC(NCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1F)C1CC1 +COCCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCCCCC(=O)NO +Nc1nc(Nc2ccc(N3CCN(C4CC5CCC4C5)CC3)c(F)c2)nn1-c1ncnc2ccsc12 +O=C(c1cc2c(O)cc(O)cc2[nH]1)N1CCC(Cc2ccccc2)CC1 +N#CC1CCCN1C(=O)C1CCC=C1C(=O)CCCc1ccccc1 +Cc1csc(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)c1 +COC(=O)C1C2CC3CCC1N3CC2=Cc1ccc(C(C)C)cc1 +COc1cc(C(=O)NS(=O)(=O)c2ccccc2C)ccc1Cn1ccc2ccc(C(=O)NCC(C)CC(F)(F)F)cc21 +CC1(C(=O)NC(Cc2ccc(O)cc2)C(=O)O)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CCOc1cc2c(cc1OCC)C(c1ccc(Cl)cc1)=NNC(=O)C2 +NS(=O)(=O)c1ccc(OC2c3ccccc3CC2N2CCCC2)c(Cl)c1Cl +CN(C)C1CCC(Nc2ncnc3sc4ccc(C(N)=O)cc4c23)CC1 +Nc1nc(C(=O)NCc2cccc3cccnc23)c2cccc(Br)c2n1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(C=Cc4cc(C)cc(C)c4)cc3)ncc2F)c1 +Cc1ccc2[nH]c(CNC(=O)c3ccc4c(c3)CNC(=O)C(CC(=O)O)N4)nc2n1 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCCCCN1C(=O)c2ccccc2C1=O +Cc1c(Br)c(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1Br +CCCCCCCn1c(=N)n(CC(=O)c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c2ccccc21 +C#Cc1cccc(Nc2ncnc3cc(OC)c(NC(=O)CCCCC(=O)NO)cc23)c1 +Cc1cccc(Nc2ccccc2C(=O)NCCCCCCCCCCCCNc2c3c(nc4cc(Cl)ccc24)CCCC3)c1C +O=C(O)Cc1ccc2c(c1)CC(NS(=O)(=O)c1ccc(Cl)cc1)C2 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cccc(C#N)c1 +O=C(Nc1c(Cl)ccnc1Cl)C(=O)c1cc(Cc2ccc(Cl)cc2)n2ccccc12 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3cn[nH]c3)nc21 +CN1C(=O)N(c2cn(C)cn2)CC1C(=O)NCc1ccc(Cl)cc1Cl +CC(C)(C)C(=O)N1Cc2n[nH]c(=O)c3cc(F)cc4[nH]c(c2c43)C1 +CC1CN(Cc2c[nH]nc2-c2c[nH]c3ncccc23)CCN1c1ccc(C(F)(F)F)cn1 +O=C(OC1CCCC1Oc1ccc(O)cc1)c1cc(O)c(C(=O)c2c(O)cccc2C(=O)O)c(O)c1 +Nc1ncc(-c2cnn(CC(=O)N3CCOCC3)c2)c2scc(-c3ccc(Oc4ccccc4)cc3)c12 +CCCCC(NC(=O)OC(C(C)C)C(C)C)C(=O)C(=O)Nc1[nH]ncc1Br +Cc1ccc(S(=O)(=O)N(CC(C)C)C(CCCCNC(=O)C(O)Cc2ccccc2)C(=O)O)cc1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(-c3ccccc3C)cc12 +CCC(CCCCCn1c(C)nc(-c2ccccc2)c1-c1ccccc1)NC(=O)Oc1ccccc1F +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)Nc1ccc2ncccc2c1 +O=C(O)c1cc(F)cc(-c2ccccc2-c2ccccc2OCc2ccccc2)c1 +CNC(=O)Nc1ncc(SCC2CCOCC2)cc1Oc1cccnc1C +COc1cc2nccc(Oc3ccc(NC(=O)Oc4ccccc4)cc3)c2cc1OC +CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(-c2ccc(C)cc2)n1 +NS(=O)(=O)OCC1CC(n2cnc3c(NC4CCc5ccccc54)ncnc32)C(O)C1O +COc1ccc2c(c1)c1c(n2C)CCCCC1CNC(=O)C1CC1 +CC1C(=O)NCC1C(=O)Nc1cc(-c2cccc(OC(F)(F)F)c2)n(C2CCC(F)(F)CC2)n1 +CCCc1cnc(N2CCC(C3Cc4cc(N5CCN(S(=O)(=O)CCC)CC5)ccc4O3)CC2)nc1 +Fc1cccc(Cl)c1-c1nc(-c2ccc(C=Cc3ccccc3)cc2)c[nH]1 +OCCCCCCCCCCCCCc1ccc[n+](CCCCCCCCCCCCCc2cccnc2)c1 +CN(c1ncnc2[nH]ccc12)C1CCC(CS(=O)(=O)N2CCC(CO)(CCO)C2)CC1 +CC(=O)N(c1ccccc1)c1ccc(C(=O)NCCCCCCC(=O)NO)cc1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(OC)cccn12 +COCC1CNC(C)CN1CC(=O)N1CC(C)(C)c2cnc(C(C)(F)F)cc21 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5COCC4CC(=O)C5)cn3)n2)s1 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)Nc3ccccc3C(=O)c3ccccc3)CCC12 +CC1CCC(C)N1CCc1cc2cc(-c3ccc(C#N)cc3)ccc2o1 +CN1CCN(Cc2cccc(-c3cc(NCCCN4CCCC4)c4ccccc4n3)c2)CC1 +N#CCNc1ncnc(-n2c(Nc3cccc(O)c3)nc3ccccc32)n1 +COc1cc(Cl)c(-c2nc(SC(C)C)nc3[nH]cc(C#N)c23)cc1OCCN1CCC(F)(F)C1 +Cc1cccc(NC(=O)NCc2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)c1 +Nc1cc(CN2CCC(C(=O)N3CCC(n4c(=O)n(CCN5CCOCC5)c5ccccc54)CC3)CC2)ccn1 +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(C#N)c3)n3c2CCOC(CF)C3)ccn1 +NC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn4c5cc6ccccc6cc5oc2c34)C1 +CCc1c2c(nc3ccc(O)cc13)-c1ccc(O)cc1OC2 +Clc1cccc(-c2nc3ccn(Cc4ccc(Br)cc4)cc-3n2)c1 +CCCCCCC(=O)Nc1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +COc1ccc(Oc2cc(N3CCC(Oc4ncc(F)c(N)n4)CC3)ncn2)cc1 +CC(C(=O)NCCF)c1ccc(OC2CCN(c3nc(N(C)C)ncc3F)C2)cc1 +O=C(CCC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1)NC(Cc1ccccc1)C(=O)O +COc1ccc(C=CC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC2CCCc3ccccc32)cc1OC +CC1(COc2ccc(-c3ccc(F)nc3F)cn2)CCn2cc([N+](=O)[O-])nc2O1 +O=c1[nH]c(C2CC(F)CN2)nc2c1oc1ccc(Br)cc12 +C=CC1(CO)C=CC(n2cc(C)c(=O)[nH]c2=O)O1 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(S(=O)(=O)N4CCN(C)CC4)cc3)cc12 +CCCS(=O)(=O)NCCCc1ccc2c(c1)C(Cc1ccc(Cl)cc1)C(NC(=O)OC(C)(C)C)CC2 +N#Cc1cccc(-c2ccc(COCCCCCN3CC(O)C(O)C(O)C3CO)cc2)c1 +CC(Cc1ccc(F)c(F)c1)C(=O)NC1N=C(c2ccc3c(c2)OCO3)c2ccccc2N(CC(=O)N(C)C)C1=O +Cc1nc(C)c(-c2ccnc(Nc3cccc(Cl)c3)n2)s1 +COc1ccc(CN2CCC(NC(=O)c3cc(=O)c4ccc(F)cc4o3)CC2)cc1 +O=C(O)c1cc(N2CCOC2=O)cc(N2C(=O)C3(CC3c3ccc(Cl)cc3)c3ccccc32)c1 +CC(C)(C)c1cc(NC(=O)C2CCCCN2C(=O)c2ccc(Cl)cc2)no1 +CCC(NC(=O)CCc1cc(-c2ccc(-c3ccccc3)cc2)no1)C(=O)NC(CC(=O)O)C(N)=O +O=C(O)CC(NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1)c1ccc(-c2ccccc2OC(F)(F)F)cc1 +NC(=O)COc1cc(-c2cnn(CCO)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(SCCNC(C)=O)ccn34)c12 +CN1C2C=C(c3ccc4c(c3)Cc3ccccc3-4)CC1CC2 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3cn4ccccc4n3)c2)c2cncnc21 +COc1cc(S(=O)(=O)c2ccc(OC(F)F)cc2)cc2c3c(oc12)CCNC3 +CC#CCn1c(=O)c2c(-c3cncn3C)n(Cc3ccnc4ccc(Cl)cc34)nc2n(CC2CC2)c1=O +[O-][S+](Cc1cc(OCc2ccc(F)cc2)ccn1)c1nc2cscc2[nH]1 +CCC(C)Nc1cc(-n2ncc3cc(Cl)c(N)nc32)ncc1C(=O)NCC(F)C(C)(C)O +C=CC=CC(C)C(OC(N)=O)C(C)C(O)C(C)CC(C)=CC(C)C(O)C(C)C=CCCc1ccccc1 +COc1cc2c(cc1OC)CN(CCNC(=O)c1cc(Br)c3ccccc3c1OC)CC2 +CN(C)CCCN(Cc1ccccc1)c1nc2c(Br)c(Br)c(Br)c(Br)c2[nH]1 +Fc1ccc(C(CCCN2CCC(c3noc4cc(F)ccc34)CC2)c2ccc(F)cc2)cc1 +CCC(O)(CC)C(F)CNC(=O)c1cnc(-n2ncc3cncnc32)cc1NC(C)C +COc1ccc(C=CC(=O)c2ccccc2-c2ccc(OC)c(OC)c2OC)cc1O +CCOC(CC(=O)O)c1ccc(OC2CCc3c2cccc3C(F)(F)F)nc1 +CCN1c2ncc(COc3cccc(O)c3)cc2C(=O)N(C)c2ccc(Cl)nc21 +COc1cc(N2CCC(N)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2ccc(NC3CCN(C(=O)c4ccccc4Cl)CC3)nc2)c1 +NCc1ccc(C(=O)Nc2ccncc2)cc1-c1cccc(C(=O)OCc2ccccc2)c1 +O=C(O)COCC1CCC(CNC(=O)N(c2ccccc2)c2cccc(Cl)c2)CC1 +CCOc1ccc(Cc2nc3cc(C(=O)N(CC)CC)ccc3n2Cc2ccco2)cc1 +COc1cc(OC)c2c(c1)OC(c1cc(OC)c(OC)c(OC)c1)C(OC(=O)Cc1cc(OC)c(OC)c(OC)c1)C2 +Cc1c(C(=O)c2nccn2C)oc2cccc(OCCCNCc3cccnc3)c12 +Cn1c(Nc2c(Cl)ccc(CNC(=O)C(C)(C)C)c2Cl)nc2cc(C(=O)NC3CC4CCC3C4)c(OCC(F)F)cc21 +Cc1ccc(-n2cc(C(=O)NCCC(=O)Nc3ccc(C4CCC(CC(=O)O)CC4)cc3)c(C(F)(F)F)n2)cc1 +CN(C)C(=O)C(CC1CC1)NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1 +CCCNc1nc(SCc2ccc([N+](=O)[O-])cc2)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Cc1ccc(CCc2cc(-n3nc(C)nc3C)nc(C)n2)nc1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC3CCCCC3)n1)C1(CC1)CN2 +O=C(Nc1cccc(-c2cn3ccnc3c(OCc3ccncc3)n2)c1)Nc1cccc(C(F)(F)F)c1 +O=C(O)c1cncc(-c2ccc(N3CCC(Oc4ccccc4Br)CC3)nn2)c1 +CC12CCC3c4cc(Cl)c(OS(N)(=O)=O)cc4CCC3C1CCC2=O +CNc1nc2cc(-c3cccc(CC(C)=O)c3)sc2n2c(C)cnc12 +CCOc1ccc(-c2nonc2NC(=O)c2ccco2)cc1OCC +Cn1c(CN2CCC(c3ccc(C(F)(F)F)cc3F)CC2)nc2ncccc21 +N#Cc1ccc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(C(=O)C(C)(C)N)CC2)CC1 +CCCCCCC(=O)OCC1(CO)CC(=Cc2ccc(OC)cc2)C(=O)O1 +COc1cc2ncnc(N(C)C3CCN(c4ncnc5[nH]ccc45)C3)c2cc1OC +Nc1ncc(C2CCCCC2)nc1-c1ccc(C(=O)NC(CO)c2cccc(Cl)c2)c(F)c1 +O=C1CC(O)CC(CC2c3ccc(F)cc3-c3cc(Cl)cc(Cl)c32)O1 +O=c1ccc(-c2cccc(C(F)(F)F)c2)nn1CC1CN(c2ncc(-c3cnn(C4CCNCC4)c3)cn2)CCO1 +O=C1CC(C(=O)Nc2cc(-c3cccc(COC(C(F)(F)F)C(F)(F)F)c3)n(-c3ccc(Cl)cc3)n2)CN1 +O=C(NC1CCN(C(=O)CCc2cccnc2)CC1)C(c1ccc(F)cc1)C1CCCCC1 +NC(=O)C(OC(=O)C=Cc1ccc(O)c(O)c1)C(OC(=O)C=Cc1ccc(O)c(O)c1)c1nnn[nH]1 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+CC(C)Oc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)cc3)ncc12 +CCc1nc2c(C(=O)NCc3ccccc3C(F)(F)F)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCCC5CCCCN5)s4)nc23)N1 +Cc1ccc(C)c(CN2CCOC(C(=O)N(Cc3cc(Cl)c4c(c3)OCCCO4)CC(C)C)C2)c1 +O=C(NCc1ccccc1)NCc1ccc2[nH]c(=O)c(-c3nccs3)c(CCc3ccccc3)c2c1 +COc1cccc(OC)c1C(=O)NCCSC1c2ccccc2COc2ccc(C(=O)O)cc21 +NC1CCCCN(c2ccncc2Nc2cccc3cnc(-c4c(F)cccc4F)nc23)C1 +CCCc1ccccc1OCCCOc1ccc2c(c1)CCC2CC(=O)O +CCC12CC(C(=O)OC)=C3Nc4cc(OC)c(O)cc4C34CCN(C(=O)C3OC31)C42 +CCCCc1ccc(OCCCCCC(O)C2CCC(C3CCC(C(O)CCCCCOc4ccc(CCCC)cc4)O3)O2)cc1 +O=C(O)CC(Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)c1n[nH]c(=O)o1 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3c(c2)CCCC3C(=O)O)cc1 +CCc1nn(Cc2ccc(-c3nc4ccncc4[nH]3)cc2F)c(CC)c1CC(=O)O +CN1CCC(COCc2cc(C(F)(F)F)cc(C3CC3)n2)(c2ccc(Cl)cc2)CC1 +COC(=O)C(C)(C)Nc1cc(C(N)=O)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +O=C1c2ccccc2CCCN1CCN1CCC(n2nnc3ccccc32)CC1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CC(O)C4)c4ccccc4n3)c(C)c12 +CC(C)(C)C(NC(=O)Cc1ccc(C#N)cc1)NC(=NC#N)Nc1cccc2ncccc12 +CCCn1c(-c2ccccc2)cc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)c1C +c1ccc(-c2nnc3c4c(c(OCc5ccncc5)nn23)C2CCC4CC2)cc1 +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3cccc4[nH]cc(C)c34)nc(N3CCC(O)C(C)(C)C3)c2C1 +COCC1CN(c2noc3cc(OCCCF)ccc23)C(=O)O1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(Cn3cccn3)c12 +CC(=O)Nc1c(Cl)cc(CNC(N)=NC(=O)C2CC(OCc3ccccc3)CN2c2ccccc2)cc1Cl +CC(C)C(CO)NCc1nc(C2CCCN(C(=O)OC(C)(C)C)C2)ccc1F +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCC#N)c12 +O=c1cc(OCc2ccc(C(F)(F)F)cc2)ccn1-c1ccc(OCCN2CCCC2)cc1 +CCc1c(S(=O)(=O)c2ccc(O)nn2)oc2ccc(Cl)cc12 +COCC1CNC(C)CN1CC(=O)N1CC2(CN(C(C)=O)C2)c2ccc(Cl)cc21 +CCc1ccc(N=C2SC(=Cc3ccnc(NC(=O)CCC(=O)O)c3)C(=O)N2C)cc1 +CC(=O)C1CCC2C3CCC4CC(O)C(N5CCOC(C(C)C)C5)CC4(C)C3C(=O)CC12C +COc1cccc(CN(C)C(=O)c2cc3ccc(-c4cn[nH]c4)cc3[nH]2)c1 +COc1ccccc1CN(C(=O)CF)c1cnccc1Oc1ccccc1 +CN(OCCNC(=O)Cc1c(C#N)ccc(NCC(F)(F)c2ccccn2)c1F)C(=N)N +Cc1cc(C)c(Oc2cc(NC3CCN(Cc4ccccc4C)CC3)nc3ncnn23)c(C)c1 +CCSC(=S)SCC(=O)CCCCCCC(=O)Nc1ccccc1 +CC(C)(c1ccc(Nc2nn(C3CCCCC3C#N)cc2C(N)=O)cc1)C(O)C(F)(F)F +OCC1CC(O)CCN1CCc1ccc(Nc2nc(-c3cccc(C(F)(F)F)c3F)cs2)cc1 +O=C(NCCCCc1cccnc1)c1ccc(-c2cccc(OC3=CC=CC=CC3)c2)cc1 +CC(=O)Nc1ccc(-c2ccnc(Nc3cccc(C#N)c3)n2)cc1 +COc1cccc(C2SC(c3ccc(F)cc3)=NN2C(=O)c2c(F)ccc(F)c2F)c1OC +CCCCCc1c(CC)c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn12 +Cc1ccc(-c2cc(C(=O)NC3CC3)cc(N3C(=O)OCC3C(C)C)c2)c(F)c1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)C4(C)CCCN4CC(C)C)ncn3)cccc2s1 +COc1ccc2c(c1O)C13CCN(C)C(C2)C1(O)Cc1c([nH]c2ccccc12)C3 +CCCOc1ccc(-c2ccc(-c3ccccc3Cl)n2CC(=O)N=C(N)NCCC2OCCO2)cc1 +COc1cccc(CNCC(O)C(Cc2cc(F)cc(F)c2)NC(=O)C(C)N2CCC(C(C)C)C2=O)c1 +Cc1nsc(-c2nnc3n2CCN(C(=O)c2ccc(C#N)cc2)C3C)n1 +CC(=O)NC1C(N)C=C(C(=O)O)OC1C(O)C(O)CO +CN1CCN(c2nc(N)nc3cc(-c4ccoc4)ccc23)CC1 +Cc1csc(NC(=O)c2cccc(Oc3ccccc3F)c2)n1 +O=C(NCc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)Nc1ccccc1 +Cc1cc(C)c(-n2c3ncccc3n3c(CN4CCC(CCc5ccccc5)C4)c(C)nc23)c(Cl)c1 +NC(=O)CC(N)C(=O)NC(Cc1ccccc1)C(=O)N1CC(OCc2ccc3ccccc3c2)CC1CCCN=C(N)N +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2cccc(Cl)c2)c(Cl)c1 +COc1cc(C(C)C)c(Oc2cnc(N)nc2N)cc1S(C)(=O)=O +O=C(CCc1ccncc1)N(Cc1nc2c(c(=O)[nH]1)COCC2)Cc1cccs1 +CCCOc1ccc(CC(CC2CCCCC2)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 +NS(=O)(=O)c1ccc(Nc2ncc3c(n2)-c2ccc(Cl)cc2SC3)cc1 +COCC(=O)N1CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C(NC(=O)c2nc3c(s2)CN(C)CC3)C1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)c1nn(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1 +CNC(=O)c1cccc(CCc2c(C(=O)O)[nH]c(=O)[nH]c2=O)c1 +Cc1cccc(N2CC(C)n3nc(COc4ccc(Cl)cn4)cc3C2=O)c1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2F)nc1-c1ccc(F)cc1C +CCCn1cc(Cc2ccc(C(=O)O)cc2OC)c2cc(NC(=O)OC3CCCC3)ccc21 +CC(C)(O)CC1CCC(c2ccc(N3CCOc4ncnc(N)c4C3=O)cc2)CC1 +Cn1cc(-c2cc3c(-c4ccccc4)n[nH]c3cn2)cn1 +CCOc1cccc(-n2cc(C(=O)N3CCN(c4cnc5ccccc5c4)CC3)nc2-c2ccc(C)cc2)c1 +CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(NS(=O)(=O)O)cc1)c1nc(-c2ccsc2)cs1 +O=C(Oc1cc(F)c(F)cc1F)c1cc2c(cn1)[nH]c1ccccc12 +CC(C)(C)OC(=O)N1C2CCC1CN(c1ccc(C(=O)Nc3ccccc3N)cn1)C2 +CN1CCCC(C(=O)Nc2ccc(-n3cc4cc(F)cc(C(N)=O)c4n3)cc2F)C1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc4c(c3)C(C)Oc3cccnc3-4)NC(=O)NC1=O)C2 +CCCCc1cc2[nH]c(C)nc(N3CCCCC3)c-2n1 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C)nc2C2CC(=O)N(C)C2)n1 +CCCCC(O)C1CC(Cc2ccc(F)cc2)CCN1CCCNC(=O)Nc1cccc(C(C)=O)c1 +Cn1ccc(CN(c2ccc3[nH]ncc3c2)c2nc(-c3ccccn3)cs2)n1 +Cc1ccc(Nc2nc(-n3cc(CO)cn3)nc3c2ncn3C2OC(CO)C(O)C2O)cc1 +c1ccc(Cn2nnnc2C(c2ccc(-c3ccccn3)cc2)N2CCCN(C3CCC3)CC2)cc1 +Cc1cn(C2C=CC(COP3(=O)OCc4cc(CCC(=O)OC(C)(C)C)ccc4O3)O2)c(=O)[nH]c1=O +CCOC(=O)C1(Cc2ccc(OCc3cc(CC)nc4ccccc34)cc2)CC1C(=O)NO +O=C(c1cccc(F)c1-c1cccnn1)N1C2CCC1C(Nc1cnc(C(F)(F)F)cn1)C2 +CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc(C(C)=O)cc3)ccc21 +CNc1cc(NS(C)(=O)=O)ccc1Nc1c2ccc(OC)cc2nc2c(C)cccc12 +CC1(c2cccc(NC(=O)c3cnc(OCC(F)F)cn3)c2)CCSC(N)=N1 +COc1cc(OC)nc(NCCn2cc(NC(=O)c3ncoc3-c3cccc(N4CCOCC4)c3)cn2)n1 +c1ccc2c(c1)[nH]c1c[nH]c3c4ccncc4nc-3c12 +COc1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +CCc1cccc(NC(=O)N2CCc3nc(-c4cnc5ccccc5c4)nc(-c4ccccc4C)c3C2)c1 +CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)N(C)CCN +CCNC(=O)Nc1ncnc2c1ncn2C1OC(COP(=O)(O)O)C2OC(c3ccccc3)OC21 +CC(C)(C)c1cc(NC(=O)C(C)(C)S(=O)(=O)c2ccc(C(F)(F)F)cc2)no1 +CCCN(CCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)cc1 +COc1ccccc1N1CCN(CCN(C(=O)c2ccccc2I)c2ccccn2)CC1 +CCN(CC)CCOc1ccc2c(c1)C1(CCOCC1)c1oc3ccccc3c1C2=O +Cc1cccc2c(=O)[nH]c(-c3ccc(C(=O)N4CCN(CC5CC5)CC4)cn3)cc12 +Cc1cc(C)cc(Cn2c(=O)[nH]c3ccc(Cl)cc32)c1 +C=CCOC(=O)NCc1c(Cl)nc(CCCC)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1cc(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)ccc1NC(=O)Nc1ccccc1C +CCCC(C(N)=O)C(CC(F)(F)F)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O +Cc1cccc(NCNC2N=C(c3cc[nH]n3)c3ccccc3N(CC(=O)C(C)(C)C)C2=O)c1 +O=c1ccn(C2CCC(OCP(=O)(O)O)O2)c(=O)[nH]1 +COc1cccc(S(=O)(=O)Nc2cccn(CC(=O)NCc3ccc(C(=N)N)cc3F)c2=O)c1 +CC(Oc1cc(-n2cnc3ccc(OC4CCCN(C)CC4)cc32)sc1C(N)=O)c1ccccc1Cl +CCNc1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +CCOC(O)=C(C#N)C(=NC1CCCCN(CC(=O)N2CCCC2)C1=O)Nc1ccc2oc(C)cc2c1 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+CC(C)(O)C1CCN(Cc2nc3c(N4CCOCC4)nc(-c4c(F)ccc5[nH]ccc45)nc3s2)CC1 +CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCC2CCN(C(=O)C3NCCC3O)CC2)cc1 +COc1cc(C2=C(c3c[nH]c4ccc(Br)cc34)C(=O)NC2=O)cc(OC)c1OC +COCCOCCOCCOCCOCCOCC1CC23CCC1(OC)C1Oc4c(OC)ccc5c4C12CCN(CC1CC1)C3C5 +O=C1c2ccccc2C(=Cc2ccc(O)cc2)c2sccc21 +CCCCc1nc2c(N)nc3ccccc3c2n1Cc1ccccc1 +COc1ccc(C(=O)Nc2ccccc2-c2nnn(-c3ccc(C(F)(F)F)cc3)n2)cc1OC +CNC(C)C(=O)Nc1ccc2c(n1)CN(C1CCCCC1)C(=O)N2c1ccc(Cl)cc1 +COC(=O)c1cccc(NC(=O)C2(CN(C)C)CCN(c3ncnc4[nH]cc(F)c34)CC2)c1 +NCC(C(=O)Nc1ccc2cnccc2c1)c1cccc(C(F)(F)F)c1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)OCC3CCCC3)CC2)C1 +CC(C)(O)C(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +CCCc1ncc(Cc2ccc3c(C(F)(F)F)ccc(O)c3n2)c2cc(OC)c(OC)cc12 +Cc1cccc2cc(Cn3nc(-c4cn[nH]c4)c4c(N)ncnc43)n(-c3ccccc3Cl)c(=O)c12 +Cc1cc(=O)n2nc(N3CC(CN)C(c4cc(F)ccc4F)CC3=O)ccc2n1 +CCN(C)c1ccc(-c2cnc(N)nc2-c2ccccc2O)cc1 +COC1(c2nc(C#N)c(-c3cc(C(=O)N4CC(c5ccc(C#N)cc5)C4)ccc3C)[nH]2)CCOCC1 +NC1(c2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)CC1 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+COc1ccc(-c2c(C(=O)NC3CCN(C(C)=O)CC3)noc2-c2cc(Cl)c(O)cc2O)cc1 +Cc1ncc(CN2CCN(C(=O)OCc3ccccc3)CC2)n1Cc1ccc(C#N)cc1 +CCCCC(NC(=O)OC1CN(C(=O)c2ccc3cc[nH]c3c2)CC1(C)C)C(=O)C(=O)NC(C)c1ccccc1 +O=C(Nc1cc(Nc2cccc3c2OCO3)ccn1)C1CC1 +CCNC(=O)C1OC(n2cnc3c(NOC)nc(C#Cc4ccc(C(C)=O)cc4)nc32)C(O)C1O +COc1ccc(NS(=O)(=O)c2ccc(S(=O)(=O)N(C)C3CCCCC3)cc2)c2ncccc12 +C=C(C)CN(CC)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3CCc2ccccc2)cc1 +Cc1cc(C)c(S(=O)(=O)NC(CCC(=O)N2CCN(c3cccc(NC4=NCCCN4)c3)CC2)C(=O)O)c(C)c1 +Cc1cc(C2CCN(S(=O)(=O)C(C)(C)C(=O)NO)CC2)ccc1-c1cccc(OCCO)n1 +COc1ccc(C(CC(C)C)NC(=O)c2cc(COc3cccc(C#N)c3)ccc2CCC(=O)O)cc1OC +C#CCNCc1cc2cc(OCCCC3CCN(Cc4ccccc4)CC3)ccc2n1C +CCCn1ccc2c(NCc3cccc(OC(F)(F)F)c3)cccc2c1=O +CC(CO)N1CCN(C(=O)OC2CCN(c3ccc(C(N)=O)cn3)CC2)CC1 +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NC(CO)C(=O)O +N=C(N)c1cccc(NC(=O)c2ccc3c(c2)CN(CCc2ccccc2)C(=O)C(CC(=O)O)N3)c1 +COc1cc(OC)cc(C2C(C#N)=C(N)Oc3c2ccc2cc[nH]c32)c1 +CC#CC1(O)CCC2(Cc3ccccc3)c3ccc(O)cc3CCC2C1 +C=CC(=O)Nc1cccc(-n2c(=O)cnc3cnc(Nc4ccc(Cl)cc4)nc32)c1 +CCn1ncnc1COc1nn2c(-c3ccccc3F)nnc2cc1C(C)(C)C +Cc1cc(Nc2nc(Cc3c(Cl)cccc3Cl)c3nc[nH]c3c2C(N)=O)ccc1N1CCNCC1 +CCC1COC2Cn3cc(C(=O)NCc4ccc(F)cc4F)c(=O)c(O)c3C(=O)N12 +CC1CN(c2nc(N3CCOCC3)c3sc(-c4ccccc4O)cc3n2)CC(C)O1 +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2cccc(OCCN(C)C)c2)cc1 +O=C1c2cc(F)ccc2N(CC2CCC2)C(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 +COC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2nc3ccc(Cl)cn3c2C)cc1 +CCNC(=O)C(=O)C(Cc1ccc(C(C)(C)C)cc1)NC(=O)C(NC(=O)CCCCC1CCSS1)C(C)C +Cn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccnc3)cc21 +O=C(O)CCCOc1cc(-c2cncnc2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(NC(=O)CC(F)(F)F)C5)cn3)n2)s1 +CCCC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(OC)c3)cc2c1Nc1ccc(CN(C)C)cc1 +N#Cc1ccc(C(c2coc3ccccc3c2=O)n2ccnc2)cc1 +COCC1CN(c2ncnc3[nH]cc(-c4cccc(C#N)c4F)c23)CCO1 +CC(C)(C)CC(=O)N(CCCCCCN1CC(O)C(O)C(O)C1CO)C1CCCCC1 +CC(C)c1ccc(O)cc1Nc1ccnc(Nc2cccc(C(N)=O)c2)n1 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+N=C(N)NCCN1C(CCc2ccccc2)CCCC1CCc1ccccc1 +Oc1ccc(Cc2nnc3ccc(-c4cccnc4)nn23)cc1 +CCn1c(=O)ccc2cnc(Nc3cccc(OC(F)(F)C(F)F)c3)nc21 +CCN(c1ccc(NC(=O)COC(=O)CCc2nc3ccccc3n2-c2ccccc2)cc1)C(C)C +Clc1ccnc2[nH]c(-c3ccc(N4CCNCC4)cc3)cc12 +CN1CCc2nc(C(=O)NC3CCCCC3CNC(=O)c3ccc(Cl)s3)sc2C1 +Cn1c(S(=O)(=O)c2ccccc2F)c(S(=O)(=O)N2CCC(CNS(=O)(=O)C(F)(F)F)CC2)c2ccccc21 +Cc1nc(-c2ccc(N3CCN(C)CC3)cc2)nc(NCCN2CCOCC2)c1C +CN1C(=O)C(CN2CCCCC2)CC1c1ccc(C2CCCC2)cc1 +CC1CN(c2ncc(C(=O)O)cc2Cl)CCN1c1nc2c(-c3cc(F)c(F)c(F)c3)cc(C(F)(F)F)cc2[nH]1 +COc1ccc2oc(C(=O)N(C)c3ccc(OC)nc3)cc2c1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)N2CCC23COC3)cn1 +N#Cc1ccc(C2(C(N)=O)CC3CCC(C2)N3C(c2ccccc2Cl)c2ccccc2Cl)nc1 +CC1CCCN1CCCOc1ccc(C(CN2CCCCC2=O)=NOC(C)(C)C)cc1 +Cc1cc2c(nn1)-c1cc(OCc3ccccc3)ccc1C2=O +CC(C)C(NC(=O)C(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCc1ccccc1 +COC(=O)CC(C(=O)OC)=C(CCCCCCCCCCCCCCCCOS(=O)(=O)O)C(=O)OC +Cc1oc(-c2ccccc2)nc1CCOc1ccc2c(c1)C(C)(C)CC2CC(=O)O 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+COc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(CC(N)=O)CC2)c(=O)n4C)cn1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(F)c1O +Nc1ncc(-c2ncccc2OC(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)CC1 +NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1 +CC(C)N1Cc2cc(OCc3cccc(-c4ccc(Cl)c(C(=O)O)c4)c3)ccc2C1=O +CCCc1sc(-c2ccc(OC)c(OCCO)c2)nc1CSc1nccc(N)n1 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN2CCSC2)cc1 +CN1CCN(C(=O)CNC2CC2c2ccc(-c3ccc(F)cc3)cc2)CC1 +O=C(C=Cc1cccnc1)Nc1ccc(C(=O)NCC(F)(F)F)cc1 +CCCCn1cc2c(nc(NC(=O)Cc3cccs3)n3nc(-c4ccco4)nc23)n1 +CNC(=N)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CC(c1ccccn1)C1CC1)CC2 +Cc1nc2c(s1)C(C(=O)NCc1ccc(Cl)cc1Cl)CCC2 +N=C(N)c1ccc(-c2cc(-c3cccc(C(=N)N)c3[N+](=O)[O-])no2)cc1 +O=C1C2C3C=CC(C4CC34)C2C(=O)N1CCCCN1CCN(c2cccc(Cl)c2)CC1 +CCCCCCCCCCc1ccc(NC(=O)C(N)CC(F)OP(=O)(O)O)cc1 +NC(=O)C1CCCN1c1nc(Nc2ncc(Cc3ccccc3)s2)cc(C(F)(F)c2ccc(F)cc2)n1 +C=C1C(=O)C23C(=O)OC4CCC(C)(C)C5C(=O)OCC45C2CCC1C3OC(C)=O +COc1cc2c(c(OC)c1OC)-c1cc3cc(C(C)O)oc3cc1C(O)CC2 +COc1cc2nc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nnc2cc1-c1cccc(O)c1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2[nH]cnc2c1 +CC1(c2nc3c(C(N)=O)cccc3[nH]2)CCCN1 +CCN(CC)CCOc1ccc(NC(=O)Nc2ccc(F)cc2F)cc1 +CCN(CC)C(=O)N(CC)c1cnc(N(CC)CC)nc1NC(Cc1ccc(OC(=O)N2CCCC2)cc1)C(=O)O +c1cc(CNCC2CCN(CCc3c[nH]c4ccc(-n5cnnc5)cc34)C2)co1 +CN(C)C(=O)NCCCCN(Cc1nccc2c1[nH]c1ccccc12)C1CCCc2cccnc21 +O=C(CCN1CCC(c2nc(-c3ccccn3)no2)CC1)NC(c1ccccc1)c1ccc(Cl)cc1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)nc3cc(CN(C)C(C)C)ccn23)n1)c1ccccc1 +COc1cccc(Oc2cc(N3CCC(Oc4ncc(F)c(N)n4)CC3)ncn2)c1 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=S)Nc1ccc(C#N)cc1)CC2 +COc1cc2cc(C(=O)Nc3ccc4c(c3)OCCO4)[nH]c2cc1OC +CCNC(=O)c1ccc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4ccccc4OC)cc32)cc1C +NC(=O)c1ccccc1OCCCN1CCN(c2cccc3c2ccn3Cc2ccccc2)CC1 +CC(C)(C)c1ccc(CCN2CCc3cc(S(=O)(=O)Nc4ccc(OCCCC5CCCCC5)cc4F)ccc3C2)cc1 +COC(=O)N1CCC(CN(C2Cc3cc(C#N)ccc3N(Cc3cncn3C)C2)S(=O)(=O)c2ccccn2)CC1 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+CCOc1ccccc1-c1ccc(-c2nc3ccc(F)cc3c(NCCCC(=O)O)c2C#N)c(C)c1 +Nc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O +COc1ccccc1CNCCCCCCNCCCCCCCCCCCCCCNCCCCCCNCc1ccccc1C +COc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1N(C)C1CCNCC1 +COc1ccc2[nH]cc(C3(CNC(=O)C4CC4)CCC3)c2c1 +CC(=O)OCCNc1c(C(=O)NCc2ccc(F)cc2F)c(=O)n(O)c2ncccc12 +O=C(NCC1OC(=O)N2c3ccc(N4CCOCC4=O)cc3OCC12)Nc1ccc(Cl)cc1 +CC(C)C(CO)NCc1nc(-c2cccc(N3CCOCC3)c2)ccc1F +CCSCc1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 +CC1=C(N2CCC3(CCN(C(C)(C)C(O)c4ccc5c(c4C)COC5=O)CC3)C2=O)COC1=O +CN(CC#N)C(=O)C(N)C12CC3CC(O)(CC(O)(C3)C1)C2 +COC(=O)c1ccccc1CCc1c(C(=O)O)[nH]c(=O)[nH]c1=O +COc1ccc(S(=O)(=O)N(Cc2ccc3c(c2)OCO3)C(CCCCNC(=O)c2ccccc2)C(=O)NO)cc1 +O=C(NCCCCN1CCN(c2cnc3ccccc3c2)CC1)c1ccccc1 +CCc1ccc(-c2c(-c3cnc(C)[nH]3)c(=O)[nH]c3ccc(C#N)cc23)cc1 +CCCN(CCC)C(=O)c1cc(C)cc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2NCCNC2=O)c1 +Cc1nc(-c2ccc(Cl)cn2)nc(NCC(NCCCCc2ccc(O)cc2)c2ccccc2)c1Cl +CC(C)(C)C(O)C(=O)N1CC(c2cc(F)ccc2F)=CC1c1cccc(O)c1 +Nc1nc(O)c2ncn(CC3(OCP(=O)(O)O)CC3)c2n1 +CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(-c4ccc5cn[nH]c5c4)c[nH]c3n2)c(OC)c1 +COc1ccc2c(c1)c(CCN)cn2S(=O)(=O)c1ccccc1 +CC(Cc1c[nH]c2c(OC(C)C)cccc12)NCC(O)c1cccc(Cl)c1 +O=C1C(=CC=Cc2ccccc2)COc2ccc(Cl)cc21 +CC1(C)CC(NC(=O)c2cccc3[nH]ncc23)c2cc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3Cl)nc2O1 +CC(C)n1cc(Nc2ncc(C3CC3)c(NCCCNC(=O)C3CCC3)n2)cn1 +COC1CC(COC2CCC(C(=O)O)CC2)N(C(=O)Cc2cc(Cl)c(NC(=O)c3cn(C)c4ccccc34)cc2Cl)C1 +COc1cc(CN2N=C(c3ccc(OC)c(OC)c3)C3CCCCC3C2=O)cc(OC)c1 +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2ccc(C#N)cc2)cn1C(C)C +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2ccc(C(=O)O)cc2)C(C(=O)O)C1 +O=C(O)CC(NC(=O)CCCCc1ccc2c(n1)NCCC2)c1ccc(Cl)c(Cl)c1 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)C2)CCN1Cc1ccc(F)cc1 +CCOC1CN(c2cccc(-c3cccc(Cl)c3OCc3cc(C)c4c(c3)CCN(C3CCOCC3)C4)n2)CCC1C(=O)O +CNC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3cnn(C4CCN(C(=O)OC(C)C)CC4)c3n2)cc1 +CC1CN(c2ncc(C(N)=O)cc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +O=C(CCC(=O)c1ccccc1)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +COc1cccc(NC(=O)c2cc(Cl)cc(Oc3cncnc3)c2)n1 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+COc1cccc(-c2cc(-c3ccc(-c4c(Cc5ccccc5)sc5ccccc45)cc3)cc(Br)c2OCC(=O)O)c1 +CN(C)c1ccc(C(=O)c2ccc(N(C)C)c3ccccc23)cc1 +Cc1nc(C2(c3cnn(C)c3)NC(c3nc(-c4ccccn4)c[nH]3)Cc3c2[nH]c2ccccc32)no1 +COC1CCCN(c2nc3c(c(Nc4ccc(C(F)(F)F)cc4)n2)CCN(c2ncccc2C(F)(F)F)CC3)C1 +COc1ccc(CCCCNCCOc2cc(F)cc3c2OCC=C3)cc1 +O=C1OC(c2ccc(F)c(F)c2)=NC1=Cc1cccnc1 +Cc1nc2ccc(Oc3ccc(Cl)cc3F)nc2c(=O)n1CC1CCCN(C(C)C)C1 +Cc1c(F)c(Oc2cccc(C(=N)N)c2)nc(N2CCN(C3CCCCC3)CC2)c1F +Cc1ccc(NC(=Nc2nc3nn(C)cc3c3nc(-c4ccco4)nn23)Nc2ccc(C)cc2)cc1 +CC(C)CNCc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +Cc1ccc(CNC(=O)Nc2ccc(OS(N)(=O)=O)cc2)cc1 +NC1=Nc2ccc(Oc3ccccc3)cc2CN1C(COC(=O)NC1CCCCC1)C1CCCCC1 +Cc1ncc(-c2cnc(Nc3cc(N4CCNCC4)ccn3)s2)cn1 +COc1ccc(-c2n[nH]c3cc(NC(=O)NCc4ccc(F)cc4)ncc23)cc1 +COc1ccc(Br)cc1CCc1c(F)cccc1C1=NCCN1 +COc1ccc(NC(=O)CN2CCN(c3nnc(Cc4ccncc4)c4ccccc34)CC2)cc1OC +CC1(c2ccc(OCCN3CCCC3)cc2)c2ccc(O)cc2CCN1c1cccc(O)c1 +N#Cc1cn(-c2cc(C(=O)O)ccn2)cc1C1=CCCCC1 +O=C(Nc1cccnc1)c1ccc(CNS(=O)(=O)c2ccccc2)cc1 +CC(C)n1cc(-c2n[nH]c3ccnc(OC4CCOC4)c23)cn1 +O=C1COc2ccc(CNC3CCN(CCN4C(=O)COc5ccc(Cl)cc54)CC3)nc2N1 +NCCCCN(Cc1nccc2c3ccccc3n(CCN3CCNCC3)c12)C1CCCc2cccnc21 +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(NC(=O)Nc3ccncc3)CCc3ccccc32)c1 +O=C(NC1CCC(CCN2CCN(c3cccc(Cl)c3Cl)CC2)CC1)c1ccsc1 +Cc1nc(-c2ccccc2F)c2c(N3CCc4cnn(C5CC5)c4C3)ncnn12 +O=C(NCC1CCNCC1)C1C(C(=O)Nc2ncc(Br)s2)C2C=CC1C21CC1 +CC(C)(C)CC(=O)NC(Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1Cc1ccccc1 +O=C(Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1)Nc1nnc(C2CCCO2)s1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(C#Cc3ccc(CO)cn3)CCC2C)c1 +Fc1ccc(-c2csc3ncnc(N4CCC(COCCN5CCCC5)CC4)c23)cc1 +O=C(NCCn1ccnc1)c1cc(N2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-] +CC(=O)c1cn(CC(=O)N2CC(F)CC2C(=O)NCc2cccc(Cl)c2F)c2cc(OCc3ccccc3)ccc12 +Cc1cc2c(OCC(O)CN3CCC(c4cccc5sccc45)CC3C)cccc2[nH]1 +CC1(C)C2CC=C(CN3CCC(NC(=O)Nc4cc(F)cc(C(F)(F)F)c4)CC3)C1C2 +CCN(CCCCNc1c2c(nc3ccccc13)CCCC2)CCC(=O)Nc1nc(-c2ccc(OC)cc2)cs1 +CCCc1c(C)nc(N2C(=O)CSC2c2c(F)cccc2Cl)nc1C +O=C(Nc1cccc(Oc2ccc3c(C=Cc4ccccc4)n[nH]c3c2)c1)c1ccccc1 +CCn1c2c(c(=O)[nH]c1=O)C(c1ccc(C)cc1)C1=C(CN(Cc3ccccc3)C1=O)N2 +CC(NC(=O)Nc1cc2[nH]nc(NC3CCOC3)c2cn1)c1ccccc1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1ccc(OCCCO)cc1 +COc1cc(-c2nc3cc(C=CC(=O)NO)ccc3n2CCCO)ccc1OCc1ccccc1 +COc1ccc(-n2cc3c(n2)c(N)nc2ccccc23)cc1 +Cc1c(COc2ccc(Cl)cc2)oc2cccc(OCCNCc3cccnc3)c12 +C=CC1(C(N)C(=O)N2C(C#N)CC3CC32)CCCCC1 +COc1ccc(-n2nc(C)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c(CN)c1 +O=C1OCC2C1Cc1c(F)cccc1C2C=Cc1ccc(-c2cccc(C(F)(F)F)c2)cn1 +COc1cc(OCc2cccc(-c3ccc(O)cn3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +COc1cc(C(F)(F)F)ccc1-c1ccnc2cc(S(=O)(=O)Nc3nccs3)c(F)cc12 +O=C(OC(C(=O)O)C(OC(=O)c1cc(O)c(O)c(O)c1)C(=O)O)c1cc(O)c(O)c(O)c1 +CC1CS(=O)(=O)CCC1N=Nc1ccc([N+](=O)[O-])o1 +Cc1nc2ccc(CN(CCO)c3ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c3)cc2c(=O)[nH]1 +COc1cc(O)ccc1-c1ccc2c(-c3nc4ccc(N5CCN(C)CC5)cc4[nH]3)n[nH]c2c1 +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3ncco3)cc2N=C(N)C1 +Oc1ncn(-c2ccc(-c3cnc(N4CCOCC4)c4nc(C=Cc5ccc6ccccc6n5)cn34)cc2)n1 +COc1ccc(Cc2cc3ccccc3s2)cc1C1OC(CO)C(O)C(O)C1O +N#CC(=C(N)Sc1ccccc1N)c1cccc(C(O)c2cccc3ccccc23)c1 +CC(C)N1CCN(C(=O)COc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +CCCN(C)c1ncc(Cl)c(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)n1 +O=C(CCCCCNc1c2c(nc3ccccc13)CCCC2)NCCc1c[nH]c2ccc(O)cc12 +CC(C)NC(=O)CN1CCN(CCc2ccc(-c3cccc(N)n3)cc2)CC1 +COc1cc2c(cc1OC)C(=O)N1C=C(c3ccc(OCCCN(C)C)cn3)CC1C=N2 +CCCN(C)Cc1sc(-c2nc(-c3cc(C)c(OCC(O)CNC(=O)CO)c(CC)c3)no2)cc1CC +CCc1ccccc1NC(=O)CCN1CCN2Cc3[nH]c4ccccc4c3CC2C1 +CC(=O)SCC(C)C(=O)N(CC(=O)O)C1CCCCCC1 +CC1=C(C(=O)OC(C)C)C(c2ccccc2C(F)(F)F)N(C(=O)OC2CCN(Cc3ccccc3)CC2)C(=O)N1 +CCN(CC)C1CCN(C(=O)c2cccc(Nc3nc4nc5c(cnn35)CCCCC(=O)Nc3cccc(c3)N4)c2)C1 +CC(C)N1CCC(Oc2ccc3cc(C(=O)N4CCOCC4)ccc3c2)CC1 +CCN(CC)CCN(C(=O)CCS(=O)(=O)c1ccccc1)c1nc2cc3c(cc2s1)OCO3 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(SCc2ccccc2B(O)O)nc1 +NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3nn[nH]c3n2)cc1 +O=C(O)c1ccc(-c2c[nH]c3ncc(-c4ccccc4)cc23)cc1 +COCc1cc(OC)c(-c2csc3c(N(C4CCC4)C4CCOC4)c(OC)nn23)c(OC)c1 +COc1ccc2c(c1)C1CN(C)C2Cc2ccc(Br)cc21 +Clc1ccc2c(NCCCNCCNc3ccnc4cc(Cl)ccc34)ccnc2c1 +CC(CC1CCC2C3CC(=O)C4=CC(=O)CCC4(C)C3CCC12C)=NO +Cc1c(C2CC2)nc2ccc(NC(=O)c3ncc(-c4ccc(F)nc4)cn3)cn12 +CC(C)NCc1c(C(=O)NC2CCCC(O)C2)noc1-c1ccc(C(F)(F)F)cc1 +Cc1ccccc1S(=O)(=O)N1CCC(N(Cc2ccc3ccc(C(=N)N)cc3c2)S(C)(=O)=O)CC1 +CC(C)n1c(=O)n(C(=O)NC2CC3CCC(C2)N3C)c2ccccc21 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC1COCC1=O +CSc1nc2cc(Cl)c(Oc3cccc(Cl)c3Cl)cc2[nH]1 +O=C(c1cccc(F)c1-n1nccn1)N1C2CCC1C(Nc1cnc(C(F)(F)F)cn1)C2 +CC(C)(COc1ccc(-c2ccc(-c3ncc(C(C)(C)C)[nH]3)cn2)cc1)C(=O)O +COc1ccccc1-n1cc2nc(-c3ccc(C)o3)nc(N)c2n1 +N#Cc1c[nH]c(C(=O)Nc2ccc(C3CCN(C(=O)CCN4CCOCC4)CC3)cc2C2=CCCCC2)n1 +NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4ccccc4)cc3)c2)c1 +CCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(-n5cnc(C)n5)ccn34)c12 +CC(C)(O)CSc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br +CC(C)N(CCN1CCC(c2noc3cc(F)ccc23)CC1)C(=O)c1noc2ccccc12 +CC1CCN(C(=O)CSc2nc(NCc3ccccc3)c3ccccc3n2)CC1 +Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC2CC2)nc1 +CCCCc1nc(Cl)c(CO)n1Cc1cccc(Oc2ccccc2C(=O)O)c1 +CC1CCCCN1CCCNC(=O)c1ccc2c(c1)C(=O)N(Cc1ccc(Cl)cc1)C2=O +CCCOCCn1c(=O)nc(NC2CCC(O)CC2)c2ncc(-c3ccc(OC)nc3)cc21 +OC1C(O)C(n2cnc3c(NC4CC5CCC4C5)nc(Cl)nc32)C2CC12 +CS(=O)(=O)c1ccc(N2CCC(C3CCN(c4ccccn4)CC3)CC2)cc1 +N#CC(Cc1ccc(-c2csc(C(=O)N3CCN4CCOCC4C3)c2)cc1F)NC(=O)C1NC2CCC1C2 +COc1ccc(C2(O)OC(=O)C(c3cccc(OC)c3)=C2Cc2ccccc2)cc1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2F)nc1-c1cc(F)ccc1C +CN1CC(c2ccc(N=Nc3ccccc3)cc2)CCC1=O +c1coc(CNc2ncnc3ccc(-c4ccc5c(c4)OCO5)cc23)c1 +Cc1ccc(Nc2nccc(N3CCN(c4ccnc5cc(Cl)ccc45)CC3)n2)cc1 +CCC(C)C(N)CN(C(=O)C1CC1c1nc(C)cs1)c1ccc(-c2ccccc2)cc1 +COc1cc2ncnc(N3CCN(C(S)=Nc4cncc(Cl)c4)CC3)c2cc1OC +O=C(NC1CCC(O)C1)c1noc(-c2ccc(F)cc2)c1Cl +c1ccc(C(c2ccccc2)C2CCC3CN2CCN3c2ccc3ccccc3c2)cc1 +CCc1ncnc(NC(C)c2ccc(OC(=O)NCCCNC(C)=O)cc2)c1Cl +Cc1nc2ccc(Oc3ccc(-c4ccccc4)cc3)nc2c(=O)n1CC1CCCN(C(C)C)C1 +CC(=O)N1Cc2cc(C#N)ccc2N(Cc2c[nH]cn2)CC1Cc1ccccc1 +CC1CC=C(C(=O)O)C(C)(c2ccc(Cl)c(Cl)c2)C1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)C1CCC(C(F)(F)F)CC1 +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccccc4)cc32)C(C(=O)N2CCCCC2)CN1 +COc1ccc(S(=O)(=O)N(CC(=O)NO)Cc2cccc(C(=O)O)c2)cc1 +CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2c(C)cccc12 +CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)C(=O)CC2)cc1 +COCCn1c(=O)cnn(-c2ccc(Cl)c(C(=O)NCC3(O)CCCCCC3)c2)c1=O +CC(Nc1cccc(F)c1F)c1cc(C(=O)N(C)C)cn2c(=O)cc(N3CCOCC3)nc12 +COC(C)(C)COc1ncnc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c1Cl +Cc1nc2cnc3cc(F)c(-c4ccc(Oc5ncccn5)cc4Cl)cc3c2n1C1CCS(=O)(=O)CC1 +CC1Cn2c(nnc2-c2cnccn2)C(=O)N1Cc1ccccc1OC(F)(F)F +CC(Cc1cc(F)ccc1F)Nc1cc[nH]c(=O)c1-c1nc2cc3c(cc2[nH]1)C(=O)N(CCN(C)C)C3 +COc1cc2nc(-c3ccc(C)cc3)cc(O)c2cc1-c1cnco1 +COC1Cc2sc(C(=O)c3ccccc3)cc2C2(CCN(Cc3ccccc3)CC2)O1 +C=CCOc1ccc(C=CC(=O)N2CC3CC34C2=CC(=O)c2[nH]c(C)c(C(=O)OC)c24)cc1 +CCOC(=O)c1c(CC)[nH]c2ccc3c(c12)CN1CCc2cc(OC)ccc2C1O3 +CC(C)(CC(=O)N1CCCCC1)NCC(=O)N1CC(F)CC1C#N +O=C(Nc1ccncn1)c1cc2c(OCCC3CCCCN3)c(-c3ccc4c(c3)CCC4)c(O)nc2cc1Cl +COc1ccccc1C(=O)C=C1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 +O=C(NCC=CCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2 +Cc1nn(C2CCS(=O)(=O)C2)c(C)c1CN(C)C(=O)C=Cc1sc2ccccc2c1Cl +CC(C)(C)COc1ccc2c(c1)C1(COC(N)=N1)c1cc(-c3cncc(F)c3)ccc1O2 +Cc1cccc2[nH]c(C3C4CC4CN3C(=O)COc3ccc(-c4ccccc4)cc3)nc12 +Cc1cc(N2CC3CN(C(=O)c4cc(F)ccc4-c4ncccn4)CC3C2)nc(C(F)(F)F)n1 +CN1CCCC1CCOCC1CCN(c2nc(N3CCC(C(N)=O)C3)nc3scc(-c4ccccc4)c23)CC1 +OC(CCN1CC=C(Cc2ccccc2)CC1)c1cc2ccccc2s1 +O=C1NC(N2CCCCC2)=NC1=Cc1c[nH]c2ncccc12 +Cc1cc(-c2cnn(C(CO)(CO)CO)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +COc1cc(CCNCC(O)c2ccc(O)c3[nH]c(=O)ccc23)ccc1OCCCc1ccccc1 +CC(c1ccc(-c2ccn(C)c(=O)c2)cc1)N1CCC(CC(C)(C)O)(c2cccc(F)c2)OC1=O +O=C(O)c1ccc2c(c1)nc(NCCCc1ccccc1)c1ccncc12 +O=C(Nc1ccc(OC(F)(F)F)cc1)Nc1ccc(OC(F)(F)F)cc1 +CCCCN(CCc1ccncc1)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)nn(C)c12 +CC(C)Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCC(C)(C)N4CCCC4)cc3)oc2c1 +CCN(CC)C(=O)CCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +Cc1cc(C#N)ccc1N1CCc2c(-n3ccc(-c4nccs4)n3)ccnc21 +Cc1ccc2c(c1)c(C(F)(F)F)c1n2CC(NC(=O)c2c(Cl)cc(-n3cnnc3)cc2Cl)(c2ccccc2)CC1 +CN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(Cc2nc3cc(F)ccc3s2)CC1F +Cc1ccc2c(c1)c(-c1cc(C)nc3ccccc13)c(C)n2CC(=O)O +CCOC(Cc1ccc2c(ccn2Cc2nc(-c3ccc(F)cc3)oc2C)c1)C(=O)O +Cc1ccc(C(CN)C(=O)Nc2ccc3cnccc3c2)cc1 +CC(NNC(=S)c1ccc(C(=O)O)cc1)=C1C(=O)N(c2ccc(C)c(C)c2)c2ccccc21 +CN(Cc1ccc(F)cc1)C(=O)C1(c2ccc(Cl)c(Cl)c2)CC1CN1CCN(C(=O)CN2CCCC2)CC1 +CC(=O)NC1CCC(CCN2CCN(c3ncc(C)c4occc34)CC2)CC1 +Cc1ccccc1-c1[nH]c2ccccc2c1CC(=O)N(Cc1ccncc1)C(C)C +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)C1CC1c1ccccc1C(F)(F)F)CC2 +O=C(Nc1cccc(-c2cn[nH]c2)c1)C(Cc1ccccc1)NCc1cscn1 +CC1CCC(C(=O)N(c2ccc(Oc3ccccc3Br)cc2C(=O)O)C(C)C)CC1 +O=C(N1CCc2cnc(NC3CCOCC3)nc2C1)N1CCCC1c1ccccn1 +CN(C)CCN1C(=O)c2cccc3cc4ccc(N)cc4c(c23)C1=O +COC(=O)CC(NC(=O)c1ccc(-c2cn[nH]c2)c(C)c1)c1ccccc1 +COc1ccc(-c2ccc3ncc4nnn(C(C)c5ccc(F)cc5)c4c3c2)cc1 +CC1CC1c1nc(-c2cnc(N)c(OC(F)F)c2)cc(N2CC3CC2CO3)n1 +Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1 +CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]c(=NC(=O)c1ccc(-c3ccccc3)s1)n2CCC(N)=O +CCCn1nc(-c2ccc(OCCCN3CCC(C)CC3)cc2)c2sccc2c1=O +CC(=O)Nc1ncnc2c1c(-c1ccc(Cl)cc1)nn2C(C)(C)C +O=C(Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)c1ccco1 +Cc1ncccc1Oc1ccc(NC(=O)N2CCc3ccccc32)cn1 +CC(C)c1nnc2ccc(-c3ocnc3-c3ccccc3Cl)cn12 +Cn1cc(-c2ccc3cnc(Nc4ccc(-n5cnc(N6CCOCC6)n5)cc4)nc3c2-c2ccccc2)cn1 +Cc1cc(F)ccc1C(O)(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)c1ccc(F)cc1C +Cc1ncnc(-c2ccc(C(=O)N3CCN(c4ccccc4)CC3)cc2)c1C#Cc1ccc(N)nc1 +O=C(O)C(CC(=O)C1(S)CCCCC1)Cc1ccc(-c2ccccc2)cc1 +NC(Cc1c[nH]c2ccccc12)C(=O)N1Cc2ccccc2CC1C(=O)O +O=C(NC1CCCC(O)(Cc2ccccc2F)C1)c1ccc2[nH]nc(-c3ccc4nccn4c3)c2c1 +COc1cc(CN(C)c2cnc3nc(N)nc(N)c3c2)cc(OC)c1 +COc1ccc(C2=C(C#N)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1OC +C=C(C)C1CC=C(C(=O)NCc2ccc(O)c(OC)c2)CC1 +Cc1ccc(-c2cc(C(=O)NCc3cnc(C)cn3)cc(-n3c(=O)oc4ccccc43)c2)cc1 +CCN(c1ccc(C(C)C)c(OCC=C(C)C)c1)c1ccc(C(=O)O)cn1 +CN(C)c1ccncc1-c1ccc(-c2csc(NC(=O)C3CC3)n2)cc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCN(Cc3cnc(Cl)s3)CC2)c2ccc(C)c(Cl)c2)CC1 +CCCN(CC=CC(C)=CC(=O)O)c1cc(C(C)(C)C)cc2c1CCC2(C)C +Clc1ccc2c(NCCCCCNc3ccnc4cc(Cl)ccc34)ccnc2c1 +Oc1ccc2c(c1)CCN(c1ccccc1)C2Cc1ccccc1 +O=C(O)CCc1ccccc1-c1cccc(-c2ccccc2OCc2c(Cl)cccc2Cl)c1 +O=C(Nc1cccc(C(F)(F)F)c1)N1CCN(CC2CCCN(C3CC3)C2)CC1 +Oc1nc2ccc(N3CC4CC3CN4)nc2c2ccccc12 +COc1cccc(O)c1C(=O)c1c(O)cc(C(=O)OC2CCCNCC2NC(=O)c2ccc(O)cc2)cc1O +CCOC(=O)c1nn(-c2ccc(OC)cc2)c(=O)c2c(N)scc12 +COc1ccc(CC2(C(=O)NC(Cc3ccc(NC(=O)c4c(Cl)cccc4Cl)cc3)C(=O)O)CCCCC2)cc1 +CN1CCC(n2cc(S(=O)(=O)c3cccc4ccccc34)c3ccccc32)C1 +CCc1c(-c2ccccc2)oc(-c2ccc(O)cc2)c1-c1ccc(OCCN2CCCCC2)cc1 +COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCOCC4)c(OC)cc23)c(C)cc1Cl +CC(C)C1NC(=O)C(Cc2cccc(Cl)c2)NCCOc2ccccc2CCCNC(=O)C(CNC2=NCCCN2)NC1=O +CCCS(=O)(=O)N1CCC(CNC(=O)c2c(Cl)cccc2Cl)(c2ccccn2)CC1 +CN1CCC2(c3cccc(O)c3)CC(c3ccccc3)CC1C2 +NS(=O)(=O)c1ccc(N2N=C(C(F)(F)F)CC2c2cccc3c2OCO3)cc1 +CCOC(=O)N1C(=S)N=C(C)C(=C(O)OCC)C1c1cccc(Cl)c1 +NC1CN(c2cccnc2)CCC1c1cc(F)c(F)cc1F +Cn1nccc1-c1cc(Cl)ccc1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1F +COc1cccc(-n2ccc3c(sc4nccc(OC)c43)c2=O)c1 +COc1ccc(-n2cc(-c3ccc(S(N)(=O)=O)s3)nn2)cc1Cl +O=C(Cc1cc(F)cc(F)c1)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CNC(=O)C(NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(C)(C)C +Cn1cncc1C(OCc1cn(Cc2cccnc2Br)c(=O)cc1-c1cccc(Cl)c1)c1ccc(C#N)cc1 +Cc1cc(C(=O)O)ccc1-c1ccc(N2C(=O)N(c3cnccn3)C3(CCN(Cc4ncccc4C)CC3)C2=O)cc1 +Cn1c(=O)c2c(ncn2CCCN2CCc3ccccc3C2)n(C)c1=O +COc1ccc(-c2coc3ccc(-c4nnc(SCc5cccc(C(F)(F)F)c5)o4)cc23)cc1 +O=C(NCc1ccncc1)c1ccccc1N1CCCN(C(=O)Cc2ccc(F)c(F)c2)CC1 +CCOc1cc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc(S(C)(=O)=O)c1 +Cc1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1Cl)=[N+]([O-])C2 +O=C(NCCC=Cc1ccccc1)c1ccccc1CN1CCc2ccc(O)cc2CC1 +CCc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1[nH]c(COC)nc1C +COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)nc3)c2cc1OC +CC(C)C(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 +Cc1cccc(NC(=O)c2cc(O)c3cccc(NS(C)(=O)=O)c3n2)c1 +c1cc2c(-c3ccnc4[nH]ccc34)c[nH]c2cn1 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+O=C1c2ccc(COc3cccc(F)c3)nc2CCN1c1ccc(F)cn1 +Cn1nc(C(F)(F)F)cc1-c1ccc(NCc2c(F)cc(F)cc2F)cn1 +CCC(=O)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +CCC(CO)c1cc(Cl)c2c(c1Cl)C(=O)N(Cc1c(C)cc(C)[nH]c1=O)CC2 +CC1=CC(C)(C)Nc2ccc(-c3ccc(C#N)s3)cc21 +CC=CC(OC)C1CCC(C)C(O)(C(=O)C(=O)N2CCCCC2C(=O)OCc2ccccc2)C1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)C(=O)NCc1ccccc1 +CCOC(=O)c1nnn2c1nc(N1CCOCC1)c1sccc12 +CCCCCC(O)C=CC1CCC(=O)N1CCc1ccc(C(=O)O)cc1 +CC(C)(C=NOCC(=O)O)Cc1c(SC(C)(C)C)c2cc(OCc3ccccn3)ccc2n1Cc1ccc(Cl)cc1 +COc1cc2cc(C(=O)CC(O)C3CC[N+](C)(Cc4ccccc4)CC3)sc2cc1OC +COc1ccc(-c2cn3c(O)nc4c(c3n2)CN(Cc2ccccc2)CC4)c(F)c1 +CC1CCN(C)C1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +CC#CC(CC(=O)O)c1ccc(OCc2cccc(OC)c2)cc1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3cccc(C)n3)n1)C(C)(C)CN2 +COc1ccc(-c2cc(O)n(-c3nc(C(=O)O)cs3)n2)cc1 +CN1C(=O)C(=Cc2ccccc2F)Sc2ccc(C(=O)NC3CCN(Cc4ccccc4)CC3)cc21 +CN1CCN(C(=O)c2cc(Nc3ncc4cc(-c5cnco5)n(C5CCCC5)c4n3)cn2C)CC1 +COc1ccc(C2CN(C)Cc3cc(OCCCN4CCN(C(C)=O)CC4)ccc32)cc1 +Cc1cc2cccc(C)c2nc1N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(C(=O)O)cc1 +O=c1c2occc2ccn1C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O +C=CCCC(CC1OC(=O)C1CCCCCC)OC(=O)CNC=O +Cc1cccc(-c2nn3c(c2-c2ccnc4ccc(OC(F)(F)F)cc24)CCC3)n1 +Cc1nccc(-c2cn(Cc3ccccc3)c3cnccc23)n1 +O=C1CCCC2=C1C(c1ccc(F)c(Br)c1)C1=C(O)CNCC1=N2 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)c3ccco3)c2cn1)c1ccccc1 +C#CCCCCOc1ccc2oc(=O)c(NC(C)=O)cc2c1 +CCC(NC(=O)C(C)NC(=O)C(C)CC(O)C(CC(C)C)NC(=O)C(NC(=O)CC(C)C)C(C)C)C(=O)O +CN1CCC23Cc4nc5cccc([N+](=O)[O-])c5cc4CC2(O)C1Cc1ccc(O)cc13 +CC1(C)CC(NC(=O)c2ccc(Oc3cccc(-c4cn[nH]c4)c3C#N)c(Cl)c2)CC(C)(C)N1 +CC(C(=O)Nc1ccc(C2CCCNC2)cc1)c1cccc(C(F)(F)F)c1 +CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3cc(Cl)cc(Cl)c3)C2=O)c(F)c1 +Cn1cc(-c2cc(S(=O)(=O)c3ccccc3)ccc2OCC2CC2)c2cc[nH]c2c1=O +CCNC(=O)Nc1ccc(-c2nc(N3CCOCC3CC)c3c(ccn3C)n2)cc1 +COC(=O)c1ccc(NC2c3cc4c(cc3C(c3cc(OC)c(O)c(OC)c3)C3C(=O)OCC23)OCO4)cc1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2C(=O)N(C)C3)n1 +CCOC(=O)C=CC(=O)N(CC(N)=O)NC(=O)C(C)NC(=O)C(C)NC(=O)CCCCC1SCC2NC(=O)NC21 +CC1Cn2c(nnc2-c2cc(F)ccn2)CN1C(=O)c1cccc(Cl)c1Cl +C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4c(F)cccc34)n2)c(OC)cc1N(C)CC[N+](C)(C)[O-] +O=S(=O)(Nc1cc(-c2cnc3ccc(Cl)nn23)cnc1Cl)c1ccc(F)cc1 +CC(Nc1nc(N)nc(N)c1Cl)c1nc2cccc(Cl)c2c(=O)n1-c1cncc(F)c1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCc1cnnn1-c1ccccc1 +Cn1ncc(C(=O)N2CCC2)c1C(=O)NCCc1nc(-c2ccccc2)nn1Cc1ccccc1 +CCCCC(NC(=O)CCc1ccccc1)C(=O)NC(CCS)C(=O)O +CC(CN)(Cc1cccc(C(F)(F)F)c1)c1nnn[nH]1 +O=C(Nc1ccc(-c2nnc(-c3ccccc3)o2)cc1)c1ccccc1Cl +Cc1cc(C)c(CN2CCc3ccc(OC(C)C)c(Cl)c3C2=O)c(=O)[nH]1 +COC1CCC2(CC1)Cc1ccc(Br)cc1C21N=C(N)c2ccccc21 +O=C(NCc1c(-c2ncco2)n(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(N2CCCCC2)nc1 +Nc1ccc(C(=O)NCCCCN2CCN(c3nsc4ccccc34)CC2)cc1 +c1ccc(CC2CCN(CCSc3nc4ccc[nH]c-4n3)CC2)cc1 +CC(C)(C)c1cc(C(=O)C=CCC2CC2)cc2c1OCC2(C)C +Cc1c(O)nc(SCc2cccc(C#N)c2)nc1Cc1c(Cl)cccc1Cl +CNc1c(Nc2cc(Cl)ccc2OCC(=O)N2CCN(Cc3ccc(Cl)cc3)CC2C)c(=O)c1=O +c1ccc(CN2CCN(CC3COC(c4ccccc4)(c4ccccc4)S3)CC2)cc1 +COCCN1CC(c2cccc(F)c2F)CCC(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)C1=O +CC1CCCN1C1CCN(c2ccc(N3CCC4(CCN(CC5CC5)CC4)C3=O)c(C(F)(F)F)c2)C1 +COc1ccccc1CCN(C(=O)c1ccc(CN2CCCC(c3ccccc3C)C2)cc1)C1CCNC1 +O=C1c2c(cc(N3CCOCC3)nc2-c2ccccc2)OCCCN1Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ncc(N)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +c1ccc2c(c1)C(=C1CN3CCC1CC3)c1ccccc1-2 +CCCCC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cc1 +CCCC(CCC)n1ccc2cc(C(=CC(=O)Nc3ccccc3OCCCC(=O)O)CC)ccc21 +CCOC(=O)Nc1cc(CO)cc(Nc2c3ccccc3nc3c(OC)cccc23)c1 +OC1COC(n2cc(-c3ccccc3)c3c(Nc4ccccc4)ncnc32)C1O +CN1CC=C(c2c[nH]c3ccc(OCc4ccccc4)cc23)CC1 +Cc1ccnc(N2CCN(CCc3c(C)n4c5c(cc(C(=O)C(C)C)cc35)CCC4)CC2)c1 +O=C(CCCCCCNc1nc(N2CCOCC2)nc2[nH]cnc12)NO +CCCCCC=C(c1cc(Br)c(OC)c(C(=O)OC)c1)c1cc(Br)c(OC)c(C(=O)OC)c1 +O=C(O)COc1cccc(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)c1 +Cc1nc(N)ccc1CNC(=O)Cc1c(Cl)ccc(NCC(F)(F)c2ccccc2)c1F +CCN1c2ncc(CCOc3ccc(C(=O)O)cc3C)cc2C(=O)N(C)c2ccc(OC)nc21 +O=C1COc2c(cccc2N2CCN(CCCc3c[nH]c4ccccc34)CC2)N1 +COc1ccc(-c2cc(C3=Nc4c(C(C)(C)C)nn(CCCO)c4C(=O)NC3)ccc2OC)cn1 +Cc1cc(F)ccc1C(=O)N1CCn2c(nnc2-c2cnccn2)C1 +CC(C)CCCOc1ccc2c(c1)Nc1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn1CC2 +CCCCc1c(C)sc2nc(-c3ccc(O)c(O)c3)[nH]c(=O)c12 +CCNC(=O)Nc1nc2cc(NCCCCN(CC)CC)ncc2cc1-c1cc(OC)cc(OC)c1 +O=C(c1ccc2ccccc2c1)N(CCN1CC=C(c2ccccc2)CC1)c1ccccn1 +O=C(NC1CCCNC1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +CCCC(=O)NCCc1nc(-c2nc(C)cs2)c(-c2ccc3c(c2)OCO3)[nH]1 +COCC1CCN(c2nc(N3C4CCC3CC(O)C4)nc3scc(-c4ccccc4)c23)CC1 +CCCc1cc(Cl)c2oc(Cc3ccc(OC)cc3)c(CCC)c2c1O +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(C(F)(F)F)cn1 +COc1ccc(-c2cc(C(N)=O)c3nc4[nH]c(OC)ccc-4c3n2)cc1 +N#Cc1cc(N2CCN(CCC3CCC(NS(=O)(=O)c4cccc(C#N)c4)CC3)CC2)cc(C(F)(F)F)c1 +CCCCN(C)c1ccc(N=Nc2ncc([N+](=O)[O-])s2)c(C)c1 +OCCCNc1cnc(F)c(-c2cncc(Nc3cccc(Cl)c3)n2)c1 +FC(F)(F)c1ccc(CCNCC(c2ccc(C(F)(F)F)cc2)N2CCN(C3CCCCC3)CC2)cc1 +FC(F)(F)c1cccc(-n2cc(-c3ccccc3NCc3ccncc3)nn2)c1 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+O=C(NCc1ccncc1)c1cnc(Oc2ccc3c(c2)CCC(c2cccc(O)c2)O3)s1 +NCCCCN(CC1Cc2ccccc2CN1Cc1ccncc1)C1CCCc2cccnc21 +COc1ccc2c(c1)C(=O)C(c1cccc(Cl)c1)=[N+]2[O-] +Oc1ccc2c(c1)C13CCN(CCc4ccccc4)C(CCC1O2)C3 +N#CC=C(Nc1cccc2c(Cl)c[nH]c12)NC1CCCCN(CC(=O)N2CCCC2)C1=O +O=[N+]([O-])c1cn2c(n1)OCC(OCc1ccc(-c3ccc(OC(F)(F)F)cc3Cl)nc1)C2 +O=C(NCc1ccc(N2CCCCCC2)c(F)c1)Nc1cccc2[nH]ncc12 +CCc1c(C)nc2c(C)cccc2c1Nc1ccc(N2CCCN(C)CC2)cc1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(F)(F)F)no4)c3)c2cc1OC +CCC(=O)C1C(c2ccc3ccccc3c2)CC2CCC1N2C +CSc1nc(N(C)NC(=O)c2ccc(F)cc2)c2ccccc2n1 +CCc1c(C)[nH]c2cc(OCCCN3CCN(c4ccccc4)CC3)c(Cl)cc2c1=O +CC(=O)c1csc(CNC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)n1 +CC1CN(Cc2ccc(N(C)C(=O)c3ccc(-c4ccc(F)cc4)nc3)cc2)CC(C)N1 +NS(=O)(=O)c1ccc(NC(=O)CN(CCN(CC(=O)O)c2ccccc2O)c2ccccc2O)c(I)c1 +OCC1OC(Oc2ccc(CCc3ccc(O)cc3O)c(O)c2)C(O)C(O)C1O +Cc1cn2c(n1)C(N1CCN(CC(C)(C)C(=O)O)CC1)=Cc1ccccc1C2 +NC(=O)c1cccc(Oc2ccc3c(c2)c(=O)ncn3Cc2c(F)cc(F)cc2F)c1C(F)(F)F 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+Cc1cc(-c2nnn(CC3CCC(C(=O)O)CC3)n2)cc(C(=O)NCc2cccc(O)c2)n1 +Cc1ccc(NC(=O)CC(CC(=O)O)c2noc(C3CC(CC(C)C)C3)c2C2CC2)c(Cl)c1 +CCOc1ccc(-c2nc(C)c(C(=O)O)[se]2)cc1[N+](=O)[O-] +O=c1[nH]cnc2c(CN3CC(O)C(O)C3CO)csc12 +CC(C)CC(=O)NC(Cc1ccccc1)C(=O)C(=O)NCCNS(=O)(=O)c1ccc(-c2ccccn2)s1 +COc1cc2c(Nc3ccc4c(c3)OCO4)ncnc2cc1OCCCN1CCOCC1 +C=CC(C)(C)C1(CC=C(C)C)C(=O)Nc2ccccc2C1=O +NC(=O)N(O)CC1CC1c1cccc(Oc2ccccc2)c1 +CN(C)CCN(C)C(=O)c1cc2[nH]c(=O)c3ccccc3n2n1 +CCc1c(C(=O)NCc2ccc(-c3ccccc3)cc2)c2c(n1CCC(O)CC(O)CC(=O)O)CCCCC2 +CC(C)(C)CCC1(C(=O)c2cnc(N)c(Cl)c2)CCNC1 +COc1ccc(N2C(=O)C(Oc3ccccc3)C2c2ccccc2[N+](=O)[O-])cc1 +Cc1cc(C(N)=O)c2c3ncnc(N4CCN(CCc5ccc(F)c(F)c5)CC4)c3n(C)c2n1 +O=C1CCCN1CCN1CCN(C2CC(c3ccc(F)cc3)c3cc(Cl)ccc32)CC1 +O=C1NCN(c2ccccc2)C12CCN(Cc1ccc3c(c1)OCO3)CC2 +O=C(NCC1(CC2CC2)CN(S(=O)(=O)c2c[nH]nn2)C1)c1ccc(Cl)cc1Cl +O=C(NCC(NS(=O)(=O)c1ccccc1)C(=O)O)c1cc2cc(OCc3ccncc3)ccc2[nH]1 +CC1CCN(CC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)C1 +Cc1ccc(C(=O)C=Cc2ccc(C(=O)NCCNc3ccnc4cc(Cl)ccc34)cc2)o1 +C=C(C)C(=O)Nc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +CCCCNc1ncc(C(=O)Nc2ccc(CN3CCOCC3)cc2)c(NC2CCC(O)CC2)n1 +Cn1cc(-c2cc3c(-c4cc(N5CC[S+]([O-])CC5)ncn4)n[nH]c3cc2F)cn1 +CN(C)Cc1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1 +Cn1cncc1CN1CC(N(CC(=O)OC(C)(C)C)S(=O)(=O)c2cccnc2)Cc2cc(C#N)ccc21 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)N3CC(C)(O)C3)c2cn1)c1ccccc1 +CCCN1CCC=C(c2c[nH]c3ccc(C(=O)OC)cc23)C1 +O=C(C1CCN(Cc2ccoc2)CC1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +Cc1ccc2c(c1)NC(c1c(F)cccc1Cl)C1=C(CC3(CCCC3)CC1=O)N2 +Cc1cc(NC(=O)C[N+]23CCC(CC2)C(OC(=O)C2(C4=CC=CC4)CCCCCC2)C3)ncn1 +COc1cccc(C)c1C1CC(Cl)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +O=C(COc1ccc2c(c1)C(O)(C(F)(F)F)c1ccccc1-2)N1CCCC1CO +O=C(Nc1nc(-c2ccccc2)cs1)C1CCCN1C(=O)C(NC(=O)N1CCOCC1)c1ccccc1 +NC(Cc1ccccc1)P(=O)(O)C(O)Cc1ccccc1 +CN1CCC(C(=O)OCc2ccc(-c3ccccc3)cc2)(c2ccc(Cl)c(Cl)c2)CC1 +CN1CC=C(c2c[nH]c3ccc(N=C(N)c4ccco4)cc23)CC1 +Oc1ccc(-c2nc(Nc3cccc(Cl)c3)nc3[nH]cnc23)cc1 +CN(C)c1ccccc1NC(=O)c1cccc2c1C(=O)c1ccccc1-2 +CCCOC1OCc2c(cc3n(c2=O)Cc2cc4ccccc4nc2-3)C1(O)CC +COc1ccc(CNC(=O)C(Cc2ccccc2)NC(=N)NC(=O)Cc2ccc(OC)c(OC)c2)cc1OC +OCCCCNc1ncc(-c2ccccn2)c(NC2CCC(O)CC2)n1 +CCCCc1ncn(Cc2ccccc2)c(=O)c1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(NC(NC(=S)Nc1ccc(F)c([N+](=O)[O-])c1)C(Cl)(Cl)Cl)C(c1ccccc1)c1ccccc1 +CN(C)CCc1ccc(Nc2ncc(Cl)c(-c3ccc(C(C)(C)N)cc3)n2)cc1 +CC(=O)OC1CCCN2C1CC(=O)C(n1cnc3ccccc3c1=O)C2(C)C +CN(C)c1cccc2cc(S(=O)(=O)NCCN3C4C5C6CC7C8C6C4C8C3(O)C75)ccc12 +CNC(=O)c1ccc2cc(C(O)(c3c[nH]cn3)C(C)C)ccc2c1C +CCCNC(=O)c1cc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2Cl)nc1OCc1ccc(F)c(F)c1 +CCOC(=O)C1=C(c2ccc(-n3c(C)nc4cnccc43)cc2)NC(C)=C(C(=O)O)C1c1ccccc1Cl +CCN(CC)C(=O)C=C(C)c1ccc(OCc2c(Cl)cccc2Cl)c(OCC(=O)O)c1 +CC1(O)CCC2CC1OOC2(C)C[S+]([O-])c1ccccc1 +CN(CCCN(C)c1cc(-c2ccco2)nc2cc(-c3ccccc3)nn12)C(=O)c1ccoc1 +CC(C)N(CCN(C(=O)Nc1ccc(F)c(Cl)c1)C1CCC2(c3cccc(CN)c3)CC2C1)C(C)C +COc1cccc(-c2nn(C3c4cc(F)cc(F)c4CC3O)c3c2CN(C(C)=O)CC3)c1 +CC(C)C1C=CC(=O)NCCC=CC(NC(=O)C(NC(=O)NC(C(=O)O)C(C)C)C(C)C)C(=O)N1 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)NCc1ccccc1)CC2 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1n[nH]cc1Nc1ncnc2sccc12 +COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3C=Cc3ccccc3)CC12C +CCC(C)C(NC(=O)C(CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCC(N)=O +CC(C)=CCCC(C)=CCCC(C)=CCOC(=O)Nc1cc(CNCCS)nc(CNCCS)c1 +COc1ccccc1N1CCN(CCCN2Cc3ccc4ccccc4c3C2=O)CC1 +COc1ccc(CNC(=O)c2cccc(NC(C)=O)c2)c(C(F)(F)F)c1 +CCCCOC(=O)NS(=O)(=O)c1sc(CCCC)cc1-c1ccc(Cn2ccnc2)cc1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(Cc1ccc(Oc3ccc(C)cc3)cc1)CC2 +Cc1cc(C)c(Oc2cc(NCCN3CCNCC3)nc(Nc3ccc(C#N)cc3)c2)c(C)c1 +Cc1cc(-c2nc3c(cnc4ccccc43)[nH]2)on1 +CC(NC(=O)C=Cc1ccccc1F)c1cccc(-c2cnccn2)c1 +c1ccc(-c2nc(NCCN3CCOCC3)c3nc(NCCN4CCOCC4)c(NCCN4CCOCC4)nc3n2)cc1 +COC1(c2cnc(S(=O)(=O)c3ccc(C(C)=NO)cc3)s2)CCOC(C)C1 +Cc1csc(C(=O)C=Cc2cc3cc(C)ccc3nc2Cl)c1 +CCOc1ccc(Cc2cc3c(cc2Cl)OCCCCCCOCC2OC3C(O)C(O)C2O)cc1 +CC(C)(O)c1cncc(-n2ncc3c(F)ccc(F)c32)c1 +Cn1c(=O)c(-c2ccccc2Cl)cc2cnc(NC3CCOCC3)nc21 +[N-]=[N+]=NCCCCn1c2ccccc2c2ccc3c(C=O)c[nH]c3c21 +O=C(N=C1SSC2=NCCN21)c1cccc2ccccc12 +COc1c(NC(=O)c2ccc(-c3ccc(F)cc3)cc2)ccc2cc(CN3CCCC3)cnc12 +O=S(=O)(c1ccc2c(c1)CCOC2)c1cc(Cl)c2oc3c(c2c1)CNCC3 +CC(C)(C)NC(=O)c1ccccc1CC(O)C(CSc1ccc2ccccc2c1)NC(=O)c1cccc(N)c1Br +O=C(O)CC(NC(=O)C1Cc2ccccc2CN1)C(=O)O +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(OC(=O)NCC(C)(C)C)C(=O)CO +O=C(OCCN1CCC(c2ccccc2)CC1)C1(c2ccc(Cl)cc2)CCCC1 +O=C(Nc1ncc(C(=O)NCCc2ccccc2)c2nc(-c3ccco3)nn12)NC1CCCCC1 +CC1CN(C)CCC1c1cc2c(cc1-c1ccccc1F)OCC1=NNC(=O)C(C)N12 +COc1ccc(C(=O)C(Cc2ccc3c(c2)OCO3)=C(C(=O)O)c2ccc3nsnc3c2)cc1 +CC1CCC(Cn2c(N3CCOC(C)(C)C3C)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CC1CCCN1CCc1ccc(-c2ccc(S(=O)(=O)NCC3CC3)cc2)cc1 +CCCOc1cc(OCCCN2CCCC2)ccc1C(=O)Nc1cccc(O)c1 +O=C(Nc1cnccc1OCC1CCOCC1)c1csc(-c2c(F)cccc2F)n1 +CCOc1ccc(C(=O)Nc2ccc(C3CNCCO3)c(F)c2)cn1 +O=C(C=Cc1ccn2c(CN3CCCC3)c(-c3ccccc3)nc2c1)NO +COc1ccc(CCNCC(O)COc2ccc(-c3nc(C(N)=O)c[nH]3)cc2)cc1OC +Nc1noc2ccc(-c3ccccc3Oc3cc(F)c(S(=O)(=O)Nc4ncns4)cc3F)cc12 +CCCCCn1cc(C(=O)c2cccc3ccccc23)c2ccncc21 +COc1cccc(CNCCCNc2ccnc3cc(Cc4cc(C)cc(C)c4)ccc23)c1O +CC(C)c1sc(Cl)nc1C(=O)NCCc1nc(C(=O)Nc2ccc3c(c2)OCO3)cs1 +COc1cccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)c1 +CC(OC1CN2C(=O)CC(O)C2C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)CC5CCOCC5)C4)c3C2)cc1C#N +COc1c(NCCCc2ccccc2)c(F)c(N)c2c(=O)c(C(=O)O)cn(C3CC3)c12 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(O)(CC#N)C2 +COC(=N)NS(=O)(=O)c1ccc(NC(C)=O)cc1 +O=C(Nc1ncnc2[nH]cnc12)c1cccc(-c2ccccc2)c1 +COC(=O)c1cccc2[nH]c3c(C(N)=O)cc(-c4cccc(OC)c4)cc3c12 +CC=CC(=O)Oc1ccc2sc(S(N)(=O)=O)nc2c1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1csc2ccccc12 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)cc1C(=O)NCC(CC(C)C)C(N)=O +COC(=O)c1csc(CN2CC(C)(C)C(Oc3ccc(C#N)c(C(F)(F)F)c3)C2=O)n1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)n[nH]2)cc1Nc1ncnc2c(N)nc(N3CC4CC3CN4)nc12 +Cc1cc(C)c(C=C2C(=O)Nc3ccc(-c4ccc5cn[nH]c(=O)c5c4)cc32)[nH]1 +Cc1ccc(C(=O)N2CC(F)(c3ccc(C#N)cc3)C2)cc1-c1[nH]nc(C)c1C +CCCSc1nc(SC(CC)C(N)=O)nc2c1ncn2-c1ccccc1 +COc1c(C=Cc2ccc(NS(C)(=O)=O)cc2)cc(-c2c[nH]c(=O)[nH]c2=O)cc1C(C)(C)C +N=C(N)c1csc(CNC(=O)C2CCCN2C(=O)C(NS(N)(=O)=O)C(c2ccccc2)c2ccccc2)n1 +CCS(=O)(=O)CCOC12COc3c(F)ccc(F)c3C1(S(=O)(=O)c1ccc(Cl)cc1)CCC(=O)C2 +CCc1[nH]c2nc(Oc3cnc4cccnc4c3)nc(N3CC4C(N)C4C3)c2c1Cl +COc1cccc(C(=O)NC(CCC2CCCCC2)C(=O)NC(CN2CCc3cc(F)ccc32)C(C)O)c1 +CC(NC(=O)c1cnn(C)c1)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 +CC(C)(C)c1ncc(CSc2cnc(NC(=O)C3CCNCC3)s2)o1 +CCOC(=O)CCCn1c(=O)oc2cc3ncnc(Nc4ccc(C(=O)OCc5ccc(Cl)cc5)cc4)c3cc21 +COc1ccc(-c2cccc3c(=O)n(-c4ccc(N5CC(C)OC(C)C5)nc4)cnc23)cc1 +CC1CCCN1CCc1cc2cc(-c3cccc(C(C)(C)O)c3)ccc2o1 +CSc1ncc(C2C(C(=O)OCc3ccccc3)=C(C)NC(C)=C2C(=O)OC(C)C)n1Nc1ccccc1 +CC(C)n1nnnc1-c1cccc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3)C2)c1 +O=C(CCCCCC(C(=O)Nc1ccc2ncccc2c1)C(=O)Nc1ccc2ncccc2c1)NO +COc1cc(F)c2[nH]c(-c3c(C)nn(C)c3C)c(C=C3Oc4ccc(NC(=O)Nc5cccnc5)cc4C3=O)c2c1 +CC(C)(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)C(N)C(=O)N1CCCC1C#N +CCCNC(=O)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +O=C(Nc1cccnn1)N1CCN(c2ccnc(-c3ccc(F)cc3F)n2)CC1 +CCN(CC)CC(=O)N1CCc2nc(Nc3ncc4c5ccncc5n(C5CCC(C)CC5)c4n3)ccc2C1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CN(CC(=O)O)Cc2cccc3ccccc23)cc1 +COc1ccccc1N1CCN(Cc2ccc(-c3ccc(F)cc3)[nH]2)CC1 +CCC(C1CC1)n1nc(C)nc(Nc2ccc(OC)nc2C(F)(F)F)c1=O +Cc1c(-c2ccc(C(C)(C)C)cc2)nc2ccc(F)cc2c1C(=O)O +Cc1c(C(=O)OC(C)C(C)(C)C)c[nH]c1C(=O)Oc1c(F)c(F)c(F)c(F)c1F +O=C(O)C1(Cc2cccc(Nc3nccs3)n2)CCC(Sc2cccc(Cl)c2Cl)CC1 +O=C(O)c1csc(-n2nc(C3=CCCCC3)c3ccccc32)n1 +CCOC(=O)c1ccc(-c2nn(Cc3ccccc3F)c3ccccc23)cc1 +Cc1cccc(NC(=O)N(C)Cc2ccc(-c3n[nH]c4c3Cc3cc(CN5CCN(C)CC5)ccc3-4)s2)c1 +O=C(Cc1ccccc1)NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1 +COCc1c(CN2CCNC(=O)C2)c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn12 +CCOc1cccc(F)c1C1CC(C)C(=O)N1Cc1cnc2ccccc2c1 +Cc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)CCC3)cc1 +CC1CCC2(O)C3(C)CC4(O)OC2(C1O)C1(O)C3(O)C(OC(=O)c2cc[nH]c2)C(O)(C(C)C)C41C +CC(C)c1cc(C(C)C)nc(N2CCN(c3ccnc(C(C)O)n3)CC2)n1 +CS(=O)(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)(c2ccccn2)CC1 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+O=C(Nc1cc(Oc2cncnc2)ccn1)c1cccc(Cl)c1 +N#CC(=C1Nc2ccccc2S1)c1ccnc(NCCc2ccc(N)cc2)n1 +Cc1c(C2CCN(Cc3ccccc3)CC2)n[nH]c1-c1ccccc1 +NC(CCc1ccccc1Oc1ccccc1)(C(=O)O)C1CC1C(=O)O +COc1ccc(-c2c(C(=O)O)c(=O)n(Cc3ccccc3OC)c3c2oc2cc(N)ccc23)cc1 +COc1ccc(C(=N)NC(C)C)cc1-c1cc2ccc(C(=N)NC(C)C)cc2o1 +Cn1cc(S(=O)(=O)Nc2ccc(-c3ccc4c(N)n[nH]c4c3)cc2)c(C(F)(F)F)n1 +CN(C)c1ccc(-c2nc3c(s2)C(O)CCC3)c(CO)c1 +CCN1Cc2cccc(Oc3nc(Nc4ccc(C(=O)NC5CCN(C)CC5)cc4OC)ncc3C(F)(F)F)c2C1=O +NC1CCC(Nc2cc(-c3nc(NCC4CCOCC4)c(Cl)cc3Cl)c(Cl)cn2)CC1 +O=C(NCC(c1ccccc1)c1ccc(C(F)(F)F)nc1)c1ccc(Cl)cc1Cl +O=C(O)CC1CCN(C(=O)OC2(C3COCC(C4CC4)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1 +CSc1ccc(Cc2cccc(-c3c(O)nc4cc(Cl)ccc4c3O)c2)cc1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C(C)O)nc1C +C#Cc1cccc(Nc2nc3cc(C(=O)O)ccc3c3cnccc23)c1 +CNCc1cc(OCc2ccc3c(C)cc(N)nc3c2)cc(C#N)c1F +COCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NCc2ccc3ncccc3c2)C(C)C)nn1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CN(C)C)c4ccccc4)ncc23)ccn1 +O=C(O)Cc1c2n(c3cc(Cl)ccc13)CC(N(CC1CC1)c1ncc(F)cn1)CC2 +O=C(O)C(Sc1nc(Cl)cc(Nc2nc(-c3ccc(Cl)cc3)cs2)n1)c1cccc2ccccc12 +CCCc1n[nH]c2c1C(c1ccc(SC)cc1)c1c(nc3c(c1N)CCCC3)O2 +CC(C)C(CO)N=C(N)c1c(O)nsc1Nc1ccc(Oc2cc(Cl)ccc2Cl)cc1 +Cn1c(=O)c(C=Cc2ccc3c(c2)OCO3)nc2ccccc21 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1ccc(C(F)(F)F)cc1 +CCCC(=O)c1cnn(-c2ccc(OC(=O)c3cn(CC(=O)N4CCN(C)CC4)c4ccc(Cl)cc34)cc2)c1C +CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)C(=O)Nc1cc(N)cc(C(=O)O)c1 +CC(NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(C5CC5)ccc34)nc12)C(=O)N1CC(C#N)C1 +O=C1N(c2cccc(Cl)c2)CCN1C1CN2CCC1CC2 +CC(C)N1CCC(NC(=O)c2ccc(OC3CCN(C4CCC4)CC3)cc2)CC1 +CC(C)(C)NC(=O)N1CCC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +CC1(C)OB(c2ccccc2NC(=O)c2ccc(Oc3ccc(C(F)(F)F)cc3)nc2)OC1(C)C +COc1cc(OC)cc(N(CCNC(C)C)c2ccc3ncc(-c4c(C)nn(C)c4C)nc3c2)c1 +O=C(c1nn(C2CCCN(CCN3CCOCC3)C2)c2c1CS(=O)(=O)c1cc(F)ccc1-2)N1CCOCC1 +CCC(NC(=O)c1ccc2c(c1)c(C)c(C)n2Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1)c1ccccc1 +O=C(O)COc1ccc(OC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c1 +O=S(=O)(NC(CCCN1CCN(c2ncc(F)cn2)CC1)C1CCCCC1)c1ccc(F)cc1 +COc1ccc2c(c1)COC(=O)N2C1CCN(CC(=O)Nc2ccc3c(c2)-c2ccccc2C3=O)CC1 +CC(C)CCN1CC(C)N(C(=O)CCc2cccnc2)C(C)c2c(F)cccc21 +NC1=NC(CF)(c2cc(NC(=O)c3cc4ccccc4cn3)ccc2F)C2CC2O1 +CCc1nc2c(n1Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)CCCC2 +CCOCn1c(Cc2ccccc2)c(C(C)C)c(=O)[nH]c1=O +COc1ccc(C2=NN(C3CCCCCC3)C(=O)C2(C)C)cc1OCc1ccccc1 +CNc1nc(Nc2cc(OC)c(-c3nccn3C)cc2Cl)ncc1C(F)(F)F +COc1cc(C(=O)N2CCC2c2noc(-c3ccccc3OC(F)(F)F)n2)c(-n2nccn2)cc1Cl +O=C(C1CCN(c2cc(Oc3ccc(F)cc3)ncn2)CC1)N1CCc2ccccc2C1 +COc1cccc(NC(=O)Nc2ccccc2C(O)CN2CCC(Cc3ccccc3)CC2)c1 +CCN(C)c1nc2ccc(C(=O)N(CCN3CCOCC3)CC(O)C(Cc3ccccc3)NC(=O)OCc3cncs3)cc2o1 +O=C(O)CSC(=O)C(CCCCNC(=O)Cc1cccs1)NC(=O)Cc1cccs1 +N#CC1CC1C(=O)N1CCN(c2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(F)c5)CC4)cc3)cc21 +CCN(CC)CCCC(CC(C)C)NC(=O)CCOc1cc(-c2cc(Cl)cc(Cl)c2)nn1-c1ccc2ccccc2c1 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+O=c1ccc(-n2ccnc2)nn1CCN1CCN(c2ccccc2Cl)CC1 +CS(=O)(=O)N1CCCC2C3c4cc5c(cc4CCN3CCC21)OCO5 +Cc1c(P(=S)(c2ccccc2)c2ccccc2)n2ccccc2[n+]1CC=Cc1ccccc1 +CCOC(=O)Nc1noc2cc(-c3c(-c4ccccn4)n[nH]c3C)ccc12 +CONC(=O)c1cnn2ccc(N3CCCC3c3cccc(F)c3)nc12 +Cc1c(F)cccc1Oc1c(C(=O)N2CCNCC2)c2ccccc2n1-c1ccccc1 +N#Cc1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)cc1 +Nc1ccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2cc3ccccc3s2)cc1 +CC(C)(O)Cn1cc(-c2nc(C(C)(c3ccc(-c4cnc(N)nc4)nc3)C3CC3)no2)cn1 +CCCCCCC(NC(=O)c1ccc(C#N)cc1)C(C)(C)C(=O)NC(Cc1ccccc1)C(=O)OCC +Cc1c(C2CC2)nc2ccc(NC(=O)c3ccc(-c4ccc(F)cn4)cc3)cn12 +COCc1cc(COc2ccc(C3(N)CCN(C(C)C(=O)NO)C3=O)cc2)c2ccccc2n1 +[H]C([H])(F)Oc1cccc(NC(=O)c2ccccn2)c1 +CC1OC(=O)C1NC(=O)OCc1ccc(C(C)(C)C)cc1 +CCCC(=O)NCCc1c(-c2ccccc2)[nH]c2ccccc12 +Cn1c(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)nnc1-c1cccnc1C(F)(F)F +COc1cc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C +FC(F)(F)c1ccc(-c2ccoc2C2=CN3CCC2CC3)cc1 +CCCN(CCC)C1COc2c(cccc2-c2ccc(OC)cc2)C1 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+N#Cc1ccc(Cn2cncc2CNC2CCN(Cc3cccc(Cl)c3)C2=O)cc1 +COCCCNc1ncnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)(F)C2)CCN1Cc1ccc(Cl)c(F)c1 +CCc1ccc(NC(c2ccc(Cl)c(C)c2)C(F)(F)F)cc1CN1CCC(C(=O)O)C1 +Cc1ccc(-c2sc(C)nc2C(=O)N2CCC2c2nc(-c3cccc(Cl)c3C)no2)cc1 +CCN(CC)C(=O)c1ccc(C(c2cccc(OC)c2)N2CC(C)NCC2C)cc1 +COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)cnc2N2CCC(O)C2)c(OC)n1 +COc1ccc(Cn2c(N=CN(C)C)nc3c2c(=O)n(CC2CC2)c(=O)n3CC2CC2)cc1 +CC(=O)OCC1OC(NC(=O)CCCn2[se]c3ccccc3c2=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +COc1ccc(C#Cc2c(N)ncnc2NC(C)c2nc3c(F)cccc3c(=O)n2-c2ccccc2)nc1 +O=C(NCc1cccc(OC(F)(F)F)c1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +N#CC1CNCC1NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +N#Cc1nccc(N2CC(S(=O)(=O)c3ccccc3C(F)(F)F)CC2C(=O)O)n1 +CN(C)c1ccc2ncc(F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)CCCC(=O)NO +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2Cc3ccncc3C2)c(-c2cncnc2)c1 +COc1cc(N2CCN(Cc3ccccn3)CC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)C4CC4)ncc3Cl)C2)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(OC4CCC4)nc3)C2)cc1 +COc1cc(C=C2SC(=O)NC2=O)ccc1Oc1ccc(C#N)c(C#N)c1 +O=C(O)CC(NC(=O)CNC(=O)c1cccc(NC2=NCC(O)CN2)c1)c1cc(Br)cc(Br)c1O +COc1ccc(Oc2c(Cl)cnn(Cc3cccc4ccccc34)c2=O)cc1 +COc1cc(-n2ccnc2)ccc1Nc1cc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +CC(Nc1ncnc(N)c1-c1cc(O)cc(F)c1)c1nn2cccc2c(=O)n1-c1ccccc1 +Cc1c(Br)c(C)c2c(c1Br)OC(C(F)(F)F)C(C(=O)O)=C2 +CC(C)(C)NC(=O)C1CN(CCc2ccccc2)CCN1CC(O)C(Cc1ccccc1)NC(=O)OC1CCOC1 +O=C(c1ccsc1)c1cnn2c1n[n+]([O-])c1ccc(Cl)cc12 +COc1cc(N2CCN(C)CC2)ccc1Nc1nc(N)n(C(=O)NCc2c(Cl)cccc2Cl)n1 +CCCCS(=O)(=O)NC1CCC(Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +CC(O)C(N)C(=O)NC(Cc1cn(C=O)c2ccccc12)C(=O)NC(Cc1ccccc1)C(=O)N(C)Cc1ccccc1 +CCOC(=O)c1ncn2c1Cn1cnnc1-c1cc(OC)ccc1-2 +N=C(N)c1cccc(Oc2ccc(NC(=O)NCC(N)=O)c(Oc3cccc(C(=N)N)c3)n2)c1 +Cc1ccc(NS(=O)(=O)c2ccc(C=CC(=O)NO)cc2)cc1 +C(=Cc1ncc2ccccc2n1)c1cn2c(-c3ccc(N4CCNCC4)nc3)cnc(N3CCOCC3)c2n1 +N=C1SC(=Cc2ccc(-c3cccc(Cl)c3)o2)C(=O)N1c1nccs1 +O=C(NCCCCN1CCN(c2ccc3ccccc3n2)CC1)c1cn2ccccc2n1 +O=C1N(Cc2ccc(CO)cc2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc(CO)cc1 +CCCCOCc1c(-c2nnc(C(C)(C)C)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1ncnc(C)c1C(=O)N1CC2CN(CCC(c3ccccc3)C3CCN(CC(F)F)CC3)CC2C1 +Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(C)c3ccccn3)cc12 +CC(C)N(C(=O)C(c1cccnc1)C(CNC(=O)NCc1cccc(F)c1)c1ccccc1)C(C)C +CC(=O)N1CCN(Cc2ccc(-c3cccc4nc(NC(=O)C5CC5)nn34)cc2)CC1 +CN(CCCNC(=O)c1cccc2cccnc12)CCCNc1n[n+]([O-])c2ccccc2[n+]1[O-] +O=C1CCN(c2ccccc2C(=O)NCc2ccc(-n3cccn3)cc2)C(=O)N1 +CN1CCN(C(=O)c2cnccn2)C(C)(c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)[nH]2)C1 +Cc1cc(-c2ccccc2S(N)(=O)=O)ccc1C(=O)NC(CCCN=C(N)N)B1OC2CC3CC(C3(C)C)C2(C)O1 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(-c3ncc(F)s3)cc2)c2ccc(OCc3ccccn3)cc12 +COc1ccccc1N1CCN(CCCN2CCCCn3c2nc2c3c(=O)n(C)c(=O)n2C)CC1 +O=C(Nc1cc(-c2ccccc2)nn1-c1ccccc1Cl)c1ccccc1 +O=C(Nc1ccccn1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +COc1cccc(OC)c1-c1cc(C(=O)NC2C3CC4CC(C3)CC2C4)nn1-c1ccnc2cc(Cl)ccc12 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(-c3cccc(OC(F)(F)F)c3)cc2)cc1 +CCNc1c2c(nc(N)n3nc(-c4ccco4)nc23)nn1C +O=C(NC1CCCCC1)c1cccn(Cc2ccccc2)c1=O +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NC1COC1 +Cc1ccc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NC(C)c2ccccc2)cc1 +COc1ccc(C2CN(c3nc(-c4ccncn4)cc(=O)n3C)CCO2)cc1 +O=C(NCC1(c2cnc(C(F)(F)F)nc2)CCC(F)(F)CC1)c1cccc(Cl)c1Cl +CCn1c(Nc2ccc(F)cc2Cl)nc2cnc(Oc3c(F)cccc3F)nc21 +CN1CCN(CCCN(Cc2nccc3c4ccccc4n(CC(=O)N4CCOCC4)c23)C2CCCc3cccnc32)CC1 +CC1CN(Cc2ccc(N(C)C(=O)c3ccc(-c4cccc(F)c4)nc3)cc2)CCN1 +CC(C)(C)c1csc(NC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)n1 +Cc1ccc(-c2nc3ccc(Br)cc3c(C(=O)O)c2CC(=O)O)cc1C +Nc1nnc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)s1 +Cc1cc(NC(=O)c2cnn3ccc(N)nc23)n(-c2cc(Cl)ccc2C)n1 +CN1CCN(c2ccc(C=C(C#N)c3ccccc3Br)cc2)CC1 +CN1CCCC(NC(=O)c2c(C(N)=O)nc3n2CCOc2cc(F)c(C#CC(C)(C)O)cc2-3)C1 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+C=C1C(=O)OC2CC3(C)OC3CCC3(C)OC3CC12 +COc1ccc(COc2nc(N3CC4CC4C3)ncc2C(=O)NCCN2CCOCC2)cc1Cl +Cc1c(C(=O)NS(C)(=O)=O)sc2ncnc(Nc3ccc(F)cc3OC(CF)CF)c12 +Cc1[nH]c2c(c1C(=O)NCCN1CCOCC1)CCCC2=C1C(=O)Nc2ccc(F)cc21 +COCCNC1=NC(=Cc2ccc3c(c2)OCO3)C(=O)N1C +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2cnn(C)c2)cn1C(C)C +CCN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +O=S(=O)(c1ccc(O)nn1)c1oc2ccc(Cl)cc2c1-c1ccccc1 +COC(=O)N1CCN(Cc2cnc(Nc3ccc(OC)nc3)c(-c3nc(C)nc(N)n3)c2)CC1 +CONC(=O)c1cc(Nc2ncnn3cc(NC(=O)OC4CCN(C)CC4)c(C(C)C)c23)c(F)cc1F +CCCCC(N)C(Cc1ccsc1)NC(=O)c1cc(NCC2CC2C)nc(N(C)S(C)(=O)=O)c1 +CN1CCN(c2ccc3c(c2)sc2nc(-c4ccc(NC(=O)Nc5cc(C(C)(C)C)on5)cc4)cn23)CC1 +Cc1c(-c2nnc(-c3ccco3)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCCn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 +Cc1nc2ccccc2nc1CCc1nc(C(=O)NCC2CCCO2)cc(N2CCCC2)n1 +Oc1cccc(-c2cc(-c3cccs3)nc3c2COc2ccccc2-3)c1 +COc1cccc(C(=O)Nc2ccc3c(c2)C(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)C(O)CC3)c1 +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)cc1 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+O=C1N(Cc2ccncc2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc2ccccc2c1 +CN(C)CCNC(=O)c1cccc2c(N)c3cccc(C(F)(F)F)c3nc12 +Cc1n[nH]c2nc3ccc(C(F)(F)F)cc3c(CN3CCCOCC3)c12 +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3cccc4[nH]nc(N)c34)c(F)c2)c1 +COC(=O)C(C)NP(=O)(OCC1C=CC(n2cc(C)c(=O)[nH]c2=O)O1)Oc1ccc(C#N)cc1 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3cccc(Cc4ccccc4)n3)C12 +COc1n[nH]c2cc(NC(=O)NC3CCCN(C(=O)OCc4ccccc4)C3)ncc12 +CCCCn1c(=O)c(C(=O)NC2CC3CCC(C2)N3C)c(O)c2cccnc21 +COC(=O)C1C(C=NCCO)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +CC1(O)C(O)C(CCl)OC1n1cnc2c(NC3CCCC3)nc(Cl)nc21 +O=c1[nH]c2c(O)ccc(C(O)CNCCc3ccc(CNCCc4ccccc4)cc3)c2s1 +CC(Nc1ncnc2[nH]c(-c3ccc(NC(=O)CCCCCCC(=O)NO)cc3)cc12)c1ccccc1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(nnc2-c2ccncc2)C1 +O=C(c1ccc(C(F)(F)F)cc1)N1CCN(C(c2ccc(Cl)cc2)c2cncnc2)CC1 +CC1(O)CC(c2nc(-c3ccc(C(=O)c4ccccc4)cc3F)c3c(N)nccn23)C1 +COc1ccc(C(=O)C(Cc2ccc(OC)c(OC)c2OC)=C(C(=O)O)c2cc(OC)c3c(c2)OCO3)cc1C +O=C1CC(NC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(Cl)cc3Cl)n(-c3ccccc3)n2)CN1 +CC(=O)NC(C)Cc1ccc(C#Cc2ccc(OCC(C)C)cc2)cc1 +Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc(C(=O)NC(C)(C)C)cc1 +COc1ccc(C2=NN(C)C(=O)C3CCCCC23)cc1OC +N=C(N)Nc1ccc(S(=O)(=O)c2ccc(NC(=N)N)cc2)cc1 +COc1ccc(-c2cc(-c3ccc(S(C)(=O)=O)c(F)c3)cnc2N)cn1 +COc1ccccc1C=NNc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Cc1c2c(n3c1CCCN(C(=O)CN)C(C)C(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +CCCCCCCCOc1ccc(-c2cc(C(=O)O)c3cnn(Cc4ccncc4)c3n2)cc1 +Cc1cncc(-c2cnc(NC3CCNCC3OCC3CCCCC3)c3[nH]c(=O)c(C)cc23)c1 +O=C(Nc1cnn(-c2ccccc2)c1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +NC(=O)C(Cc1ccccc1)NC(=O)C(CS)NC(=O)C(F)(F)F +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)NCc2cc(C(F)(F)F)ccc2Oc2ccnc(N3CCOCC3)n2)cc1 +COc1cc(OC)cc(C(C)N(C(=O)C2CNCCO2)C2CC2)c1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cccc(C5CCNCC5)c4)nc23)cc1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2ccncc12 +CCNc1nccc(-c2nc(C3CC3)[nH]c2-c2cc(F)cc(NS(C)(=O)=O)c2Cl)n1 +CSc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1ccc2c(c1)OCO2 +N=C(N)c1ccc(-c2cc(-c3ccc(C(=N)N)cn3)on2)cc1 +CC(C)n1cnc2c(-c3ccc(F)c(-c4ccc(S(=O)(=O)C(C)C)cc4F)c3)cnnc21 +CC(OCC(O)CNC(C)(C)Cc1ccc2ccccc2c1)c1cccc(-c2ccc(C(=O)O)cc2)c1 +[C-]#[N+]c1cccc(-c2cc(C(=O)Nc3ccc(C4CNCCO4)cc3)n[nH]2)c1 +Cn1cncc1C(OCc1ccc(C#N)nc1-c1cccc(Cl)c1)c1ccc(C#N)cc1 +c1cc(-c2n[nH]c3ccc(-c4nnn[nH]4)cc23)cs1 +Cc1ccc(Oc2ccc(N(CC(O)C(=O)NO)S(=O)(=O)Cc3ccccc3)cc2)cc1 +CCCCCn1cc(C(=O)NC2C3(C)CCC(C3)C2(C)C)c(=O)c2ccc(Sc3ccccc3)cc21 +Cc1cc(NC(=O)CC(=O)O)c2c(c1Oc1ccc(O)c(CCc3ccc(F)cc3F)c1)CCC2 +O=C(NC(c1ccccc1)c1ccccc1)c1ccc2nc(NC3CCC(O)CC3)c3nccn3c2c1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc[n+]([O-])c2)c1F +CC(=O)Nc1cc(-c2ccc(F)cc2)cc(-n2cnc3cc(-n4cccn4)ccc32)c1 +Cc1nnc(C(C)C)n1C1CC2CCC(C1)N2CCCN(C(=O)NCc1ccccc1)c1ccccc1 +O=C1NCC(C(=O)Nc2cc(-c3cccc(COCCC(F)(F)F)c3)n(-c3ccccc3)n2)N1 +COc1ccc2c(c1)-c1[nH]nc(NCc3c(C)cccc3Cl)c1C2 +CC(C)(C(=O)Nc1nncs1)C1c2ccc(-c3ccc(C(=O)N4CCOCC4)cc3)nc2Oc2c(F)cccc21 +NC(=O)c1cc(N2CCC(Oc3ccccc3C(F)(F)F)CC2)no1 +NC(=O)c1cccc2c(NCc3ccc(F)cc3F)ncnc12 +Cc1cc(N2CCNCC2)c2c(c1)N(S(=O)(=O)c1ccccc1C#N)CCO2 +O=C(OC1C[N+]2(CCc3ccccc3)CCC1CC2)C1c2ccccc2Oc2ccccc21 +O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cc(Oc3ccccc3)ccc21 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2nc(CCc3ccccc3)cs2)cc1 +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)Nc1cnc2ccccc2c1 +CNc1nccc(-c2ccc3c(c2)CCC(C)N3C(=O)c2ccc(O)cc2O)n1 +Cc1ncc(NC(=O)c2cc(NC(=O)c3cccc(C(F)(F)F)c3)ccc2Cl)s1 +CCCCCCCCCCCC(=O)NC(CNC(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1 +Cc1nc2c3ccccc3nc(SCc3nc(-c4ccccc4)cn3C)n2n1 +Cc1ccc(CN2CCCC2)cc1NC(=O)c1ccc(Nc2ncc(C)c(-c3ccc(OC(F)(F)F)cc3)n2)cc1 +Cc1cc(N2CC3CCN(C(=O)c4cc(F)ccc4-n4nccn4)CC32)ncn1 +O=C(NC1c2ccccc2CC1O)C(Sc1ccccc1F)C(O)C(O)C(Sc1ccccc1F)C(=O)NC1c2ccccc2CC1O +COCCCCN1CCC23Cc4nc5ccccc5cc4CC2(O)C1Cc1ccc(O)cc13 +Cc1cc(C)cc(Sc2c(C)c(=O)[nH]c(=S)n2COCCO)c1 +Cc1nc(N2CCC(N3CCCC3=O)CC2)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +CNC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4cccc(Cl)c4)c(F)cc3F)cc1CC2 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCN(CC(=O)O)CC3)cc12 +Cc1csc(C(=O)NC23CCCC(C#Cc4cnccn4)(CC2)C3)n1 +Cc1cccc(-n2cc3c(n2)c(NC2CCCC2)nc2ccccc23)c1 +O=C1NS(=O)(=O)c2cc(-c3cnc(N4CCOCC4)c4nc(CCc5ccc6ccccc6n5)cn34)ccc21 +Cc1noc(C)c1S(=O)(=O)NC(CCC(=O)N1CCC2(CC1)CCN(c1ccc(C(=N)N)cc1)C2=O)C(=O)O +O=C(Nc1cccc(-c2ccnc3c(C(=O)c4cccs4)cnn23)c1)c1ccco1 +Cc1cc2c3c(c1)n(CC(=O)Nc1ccc4c(c1)CC1(C4)C(=O)NC(=O)N1C)c(=O)n3CC(=O)N2 +Cc1ccc(CCc2cccc(C3OC(CO)C(O)C(O)C3O)c2)cc1 +CN(C)CCNc1ccc2c(=O)n(CCN(C)C)c3c4cc5c(cc4ncc3c2c1)OCO5 +CCc1ccc(Cc2nn(C3OC(CO)C(O)C(O)C3O)c3ccccc23)cc1 +NC(CC(CC=Cc1ccc2ccccc2c1)C(=O)O)C(=O)O +N=C(N)Nc1ccc(Cc2ccc(N3C(=O)N(Cc4ccccc4)N=C(C4CCCCC4)c4ccccc43)cc2)cc1 +COC(=O)C1(C)C(O)CCC2(C)c3cc4c(cc3C(O)CC21)[nH]c1ccccc14 +O=C(CCCN1CCc2c([nH]c3ccccc23)C1)c1ccccc1 +CC(O)c1ccc(N2CCN(c3nnc(Cc4ccccc4)c4ccccc34)CC2)nc1 +Clc1cccc(N2CCN(CCCCCCN3CCN(c4cccc(Cl)c4)CC3)CC2)c1 +Oc1ccc(CC2CCN(CCCCc3ccccc3)CC2)cc1 +CC(=O)N1CCc2cc(Br)cc(S(=O)(=O)N(CC(C)C)CC(C)C)c21 +O=C(Nc1ccc([N+](=O)[O-])cc1)Nc1cccc(-c2cccc(N3CCCC3)n2)c1 +COc1cc2nccc(Oc3ccc(NC(=O)NC4CC4)c(Cl)c3)c2cc1C(N)=O +Cc1nc(-c2cccc(C=CC(=O)NO)c2)n(CCN2CCOCC2)c1-c1ccccc1 +CCOc1ccc2cc(-c3nn(CC(C(C)C)N(C)C)c4ncnc(N)c34)ccc2c1 +Cc1cccc(-n2cc(-c3ccc(S(N)(=O)=O)s3)nn2)c1 +NC1(c2ccc(-c3nc4ccc(-c5ncc[nH]5)cn4c3-c3ccccc3)cc2)CCC1 +CC(C)(C)c1ccccc1N1CCN(C(=O)c2ccc(OCC3CCNCC3)cc2)CC1 +Cc1ccc(NC(=O)c2ccc(N(CCCl)CCCl)cc2)cc1Nc1nccc(-c2cccnc2)n1 +CN1C(=N)NC(C)(c2sc3c(-c4cnn(-c5ccccc5)c4)cccc3c2F)CS1(=O)=O +CC(=O)Oc1ccc2c(c1)Oc1cc(OC(C)=O)ccc1C21OC(=O)c2ccccc21 +COc1ccc2c(Oc3ccc(NC(=O)c4c(CN5CCCC5)n(C)n(-c5ccccc5)c4=O)cc3F)ccnc2c1 +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(Cl)nc4)cc3)nc(N(C)C)nc2c1 +C#CCN(Cc1ccc(OC)cc1)c1cc(OCC2CC2c2ccc(OC)cn2)nn(C)c1=O +CC(C)C(C(=O)NC(CC(=O)O)C(=O)O)N(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1 +CCOC(=O)C(C)NP(=O)(OCC1OC(n2cc(F)c(=O)[nH]c2=O)CC1O)Oc1ccccc1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(=O)n(C)ccc2n1CC(=O)O +CCC1=CC2C3CCC(=O)C3(C)CCC2C2(C)CCC(=O)C=C12 +COc1cccc2c1nc(Nc1c(C)cccc1Cl)c1cncn12 +CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(C(Oc2cccc(Cl)n2)c2ccc(OC(F)(F)F)cc2)CC1 +COC(=O)COc1ccc2c(NC(=O)N3C(C(=O)NCc4cccc(Cl)c4F)CC4CC43)cn(C(N)=O)c2c1 +Cc1ccccc1C(=O)Nc1ccc2nc(-c3ccc(N(C)C)cc3)oc2c1 +c1cc(C2=NCCN2)ccc1CC1CCCN(c2ccc(C3=NCCN3)cc2)C1 +CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)C3CCC(NCc4cccc(C(F)(F)F)c4)CC3)sc12 +CC(NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)c1cccc(OCC2CC2)c1 +CC(C)(C)NC(=O)C1CCC2C3CCC4=C(O)C(=O)CCC4(C)C3CCC12C +NC(=O)c1ccc(F)cc1OCc1ccc(F)c(C(=O)N2CCNCC2)c1 +CC(=O)C1CCC2(C)C3CCC4C(C)(C)C(=O)CCC45CC35CCC12C +Cn1c(=O)c2c(nc(Br)n2CCSc2nc3ccccc3o2)n(C)c1=O +Cc1cccc(C)c1CNc1nccc2c(C)c(C)[nH]c12 +Cc1cccc(C(CC(C)C)NC(=O)c2cc(COc3cccc(C#N)c3)ccc2CCC(=O)O)c1 +O=C(c1ccc(-c2ccccc2)cc1)c1cc(C(=O)C(F)(F)F)n(-c2cnn(O)c2)c1 +Cn1ccc2ccc3c4[nH]c5c(CCCNCCO)cccc5c4c4c(c3c21)C(=O)NC4=O +COC(=O)CCC(=O)Nc1nc2c(s1)CC(NC(=O)c1cc(Cl)c(Cl)[nH]1)CC2 +O=C(C=Cc1ccc(OC(F)(F)F)c(F)c1)NCC1CCN(Cc2cc(Cl)cc(Cl)c2)C(=O)C(CCN2CCCCC2)N1 +Cc1ccc(O)c(Cn2c(NC3CCN(CC(O)C(C)(C)C)CC3)nc3c(C)cccc32)n1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(Cn5cc6ccccc6n5)C4)cc23)ccn1 +CN(C)CC(C)(C)Oc1ccc(-n2ccc(OCc3ccccc3)cc2=O)cc1 +CNCC1CCC(C(=O)N2CC(c3ccc(C)cc3)C(c3ccc(C#N)cc3)C2)CC1 +CCNc1nc2cc(C#CCCO)c(Cl)cc2nc1NCCCN1CCN(C)CC1 +Cn1nc(C(F)(F)F)cc1-c1cnc(NC(=O)c2ccc(Cl)cc2)s1 +Cc1cccc(CNC(N)=NC(=O)c2ccc(CC(N)C(=O)O)cc2)c1N1CCCCC1 +Cc1ccc(Nc2nc(NCc3ccccc3)c3ccccc3n2)cc1 +CN(C(=Nc1ccc(C(=O)NCCc2ccc(Cl)cc2Cl)cc1)NC1CCCCC1)C1CCCCC1 +O=C(CCC1=CCCN(CCc2ccc(C(F)(F)F)cc2)C1=O)NO +CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc([N+](=O)[O-])cc3)ccc21 +CCC(NC(=O)CCc1ccc(-c2cccc([N+](=O)[O-])c2)cc1)C(=O)NC(CCC(=O)O)C(N)=O +Cn1cc(-c2ccc(-c3cnc(N)c4ccc(-c5nccn5C)nc34)cc2)cn1 +COCCN1CC2C(C1)C2c1cc(-c2cnc(N)c(Cl)c2)nn1CC1CC1 +CC1CCC2(C)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C(=O)O)C5CCC43C)C2C1C +CS(=O)(=O)c1ccc(-c2cc3c(NC4CCCNC4)ncc(C(N)=O)c3s2)cc1 +CN(c1ccc(NC(=O)NC2CCCC2)cc1)c1ccnc(Nc2cccc(CS(C)(=O)=O)c2)n1 +OC1CCC(Oc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 +NC1CCCN(c2cccc(-c3n[nH]c4cnc(-c5cncs5)cc34)n2)C1 +N#Cc1ccccc1Cn1c(N2CCCC(N)C2)nc2[nH]c(Br)cc2c1=O +COc1ccc(NC2=CC(=O)C(=O)c3ccccc32)cc1 +COCCN1CCC(c2cc(C)c3nc(-c4c(NCCn5cc(Cl)cn5)cc[nH]c4=O)[nH]c3c2)CC1 +CN(C(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1)N(C#N)CCc1ccccc1 +Nc1nc(N2CCN(C(=O)C(Cl)Cl)CC2)nc2nc(-c3ccco3)nn12 +CCc1cc2c(cc1N1CCN(C(=O)C3CNC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +Cc1ccc2c(c1)oc(=O)n2CCOc1ccnc2cc(OCCN3CCOCC3)ccc12 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2ccccc2)CC1 +CCCCCCCCC=CCCCCCCCC(=O)OCC(CO)OC(C)=O +CCOc1c(C#N)cc(Br)cc1CNCCCNc1cc(O)c2ccccc2n1 +CCN1c2ncc(CCOc3ccc(CCC(=O)O)cc3C)cc2C(=O)N(C)c2cccnc21 +Cc1nc(N)c(-c2cnn(C3CCN(C)CC3)n2)nc1-c1cnc2ccccn12 +O=C(Nc1ccc(Cl)nc1)c1ccc(-c2ccccc2)cc1 +COc1ccc(CNc2cc(-c3[nH]c(SCc4ccccc4)nc3-c3ccc(F)cc3)ccn2)cc1 +COC(=O)CCC(C(=O)C=Cc1ccc(O)c(OC(F)(F)F)c1)C(=O)C=Cc1ccco1 +CCOC(Cc1cccc2c1ccn2Cc1nc(-c2ccccc2)oc1C)C(=O)O +N#Cc1ccc(C(=O)Nc2cc(Cl)c(F)c(C3(CF)N=C(N)OC4CC43)c2)nc1 +O=C(Cc1nc(N2CCOCC2)cc(=O)n1-c1ccccc1)N1CCc2ccccc21 +CSCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 +CC(NC(=O)C1(C)CC1)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CC(c1ccc(-c2ccc(F)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +O=C(NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCCN2CCC=N2)N1)c1ccc2ccccc2c1 +Cc1nc(N2CCCCC2)c2c(C)c(C(=O)N3CCN(c4cccc(Cl)c4)CC3)sc2n1 +CN(C)C(=O)C1(Cc2cccc(Nc3cc[nH]n3)n2)CCC(Oc2cccc(Cl)c2F)CC1 +COc1ccc(COc2cccc(-c3ccc4sc(C(=N)N)cc4c3)c2)cc1 +O=C(CNC(=O)c1cccc([N+](=O)[O-])c1)NC1CCN(Cc2ccc(Cl)cc2)C1 +Cc1ccc(C=Cn2nc(C(C)(C)C)cc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CC(C)OC(C)C3)c3ccccc23)cc1 +COc1cccc2cc(C(=O)Nc3ccc(-c4ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc4)cc3)oc12 +O=S(=O)(c1ccc2c(c1)OC1CNCCC21)c1ccccc1-c1ccccc1 +COc1ccncc1-c1ccc(NS(C)(=O)=O)cc1OCC(F)(F)F +Nc1ncc(-c2ccc(C3(c4noc(-c5cnccc5Cl)n4)CCC3)cn2)cn1 +CC1CN(C(=O)c2ccccc2)CCN1S(=O)(=O)c1c[nH]c2c(-n3cncn3)ncc(F)c12 +OC12C3C4CC5C6C4C1C6C(C53)N2Cc1cccc(I)c1 +Cc1cc(N2CCC(N3CCCC3C)C2)ccc1NC(=O)c1ccccc1F +COc1ccc(C(=O)C(=NC2CCCC2)n2ncc(C#N)c2N)c(F)c1 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+N#Cc1c(N)nc(NCCCC2CCN(Cc3ccccc3)CC2)c(C#N)c1-c1ccccc1 +CC(NC(=O)C1(NC(=O)C(F)(F)F)CC1)c1ccc(-c2cccc(F)c2-c2nnn(C)n2)cc1F +COc1cccc(CO)c1C(=O)N1CCC2CN(c3cnc4ccccc4n3)C2C1 +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Nc2ccncc2)N2C1=NC1CCCC12 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(C(C)C)C(=O)C4)ncn3)c2c1 +O=C(O)c1cccc(-c2ccc3c(c2)C(=NNc2nc4ccccc4s2)CCN3)n1 +CCCCCN(CCCCC)c1ccc(C=C(C#N)C(=O)O)cc1 +COc1cc(Nc2nc3c(c(COC4CCCC4)n2)COCC3)ccc1-n1cnc(C)c1 +O=S(=O)(O)Nc1ccc(-c2nc3ccccc3s2)cc1Cl +Cc1cc(CNC(=O)c2cc(-c3ccc(OCc4ccccc4)cc3)n(C)n2)ccc1OC(C)(C)C(=O)O +CN1CCN(c2nc(COC(c3ccc(C#N)cc3)c3cncn3C)ccc2C#N)CC1 +CCNc1cccc2c(S(=O)(=O)Nc3ncc(Br)nc3OC)cccc12 +NC1CCC(Nc2cc(-c3ccc(F)c(NCC4CCOCC4)n3)c(Cl)cn2)CC1 +CCOC(=O)C1=C(C)NC(C[S+]([O-])c2ccccc2C)=C(C(=O)OCC)C1c1ccccc1C(F)(F)F +CCC(=O)NC1c2cncc(-c3ccc4c(c3)CCC(=O)N4C)c2CCC1F +COc1ccc(CCNc2nc(N)c3nc(-c4ccco4)sc3n2)cc1 +CCCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1C +COc1ccccc1-c1nc2c(C(N)=O)cccc2[nH]1 +CCn1c2ccccc2c2cc(S(=O)(=O)Nc3ccc(OC)cc3OC)ccc21 +O=C(Cc1ccccc1)NC(=S)Nc1ccc(Oc2ccnc3cc(C(=O)N4CCOCC4)sc23)c(F)c1 +Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1Br +CNc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 +O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(N2CCCNC2=O)CC1 +CC(C)n1c(CCC(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c(-c2ccccc2)c1C(N)=O +CN1CCN(c2cc(N(C)S(C)(=O)=O)c3nc(C(=O)NCc4ccc(F)cc4)c(O)c(=O)n3c2)CC1 +CCC(NC(=O)N1CC(=NOc2ccccc2)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1cccc(C(=O)O)c1 +CC(C)Nc1cc(Nc2ccc3nsnc3c2)ncc1-c1nnc(C(=O)N2CCC(O)C2)s1 +O=C(CC1CC1)NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1 +CC(=O)NCCc1cccc2ccc(OCCCCOc3ccc4c(c3)C(CCNC(C)=O)CCC4)cc12 +NC(=O)c1ccc(F)c2c1CC(N(CCc1c[nH]c3ccc(F)cc13)CC1CC1)CO2 +CC(CCNC(=O)c1c(Cl)cncc1Cl)N1CCC(N(Cc2cccc(C#N)c2)c2ccc(C#N)cc2)CC1 +CC(=O)NCCC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1N1CCN(C)CC1 +COc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCn1ccnc1[N+](=O)[O-] +O=C(CCS(=O)(=O)c1ccc(Cl)cc1)Nc1nc(-c2ccncc2)cs1 +CCC1COC(c2ccc3c(C(=O)NCc4ccc(F)c(F)c4)c(C(C)C)n(Cc4ncco4)c3c2)=N1 +CCCc1nc2c(n1Cc1ccc(-c3ccccc3S(=O)(=O)Nc3onc(C)c3C)c(CO)c1)C(=O)CCCC2 +CC[n+]1c(C=Cc2ccc(F)cc2)ccc2ccccc21 +CCC(=O)N1CCc2nc(-c3cc(C(=O)N4CCC(c5ccc(C#N)cc5)CC4)c(C)cc3C)[nH]c2C1 +COc1cnc2c(NCc3nnc4ccc(-c5ccc(F)c(Cl)c5)cn34)ccnc2c1 +CC12CC(O)C(C)(O1)C1C(=O)N(c3ccc(C#N)c(I)c3)C(=O)C12 +Cc1cccc(-n2c(SCc3cc(=O)n4ccsc4n3)nc3ccccc32)c1 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(Cl)cc1 +c1cc(-c2nnc[nH]2)c2nc(N3CCOCC3)c3ccsc3c2c1 +Cc1ccccc1-c1ccc(-c2nc(-c3ccc4c(c3)CN(CCC(=O)O)CC4)no2)cc1C(F)(F)F +CC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cc(Cl)cc(C(F)F)c1 +Cc1ccc(N(CC(=O)Nc2cccc(Cl)c2C)S(=O)(=O)c2ccccc2)cc1 +O=c1ccc2c([nH]1)CCCC2NCCCCCCCCCCNC1CCCc2[nH]c(=O)ccc21 +FC(F)(F)c1ccc(-c2cnc(Nc3cccc4cnccc34)o2)cc1 +CC1CN2c3c(cc4c(N5C(=O)OCC5C5CCOCC5)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +COCCc1sc[n+](CCOc2ccc(-c3ccc(OCC[n+]4csc(CCOC)c4C)cc3)cc2)c1C +O=C(N1CCCC1)N1Cc2c(-c3ccc(F)cc3)ncn2-c2ccccc21 +CC(C)CC(O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)C2CCCNC2)CC1 +O=C(O)COc1cccc2c1CCC(Cn1ncc(-c3ccccc3)c(-c3ccccc3)c1=O)C2 +Nc1ccccc1NC(=O)CCCCCNC(=O)c1cc2ccccc2cn1 +CCCc1nc(CN2CCN(c3ccccn3)CC2)c(C=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(C)OC(=O)C(C)NP(=O)(COC1C=C(F)C(n2cnc3c(N)ncnc32)O1)Oc1ccccc1 +Nc1ccc(-c2c[nH]c3cc(-c4cncc(OC5CCC(N)CC5)n4)ccc23)c(F)n1 +c1ccc(CN2CCN(c3cccc4[nH]ccc34)CC2)cc1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NC1CCCN(S(C)(=O)=O)C1 +CCNc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NC1CCC(C(C)(C)O)CC1 +Nc1n[nH]c2cc(-c3ccc(C(=O)O)cc3)nc(-c3ccc(Oc4ccccc4)cc3)c12 +Cc1cc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)sc4n3)c2)n(C)n1 +CN(CCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N1CCCC1)CC2)S(=O)(=O)CC1CC1 +O=C(CCCCCCCSc1nc(=O)c(Cc2cncnc2)cn1CCc1ccccc1)c1ccc(Cl)cc1 +Fc1ccc(C2(CCNCc3ccccc3)CCOC3(CCCCC3)C2)cc1 +CC(=O)OCC1OC(NS(=O)(=O)NO)C=CC1OC(C)=O +COc1cc(Nc2nc3c(s2)CCCC3c2ccccc2)ccc1-c1nnc(C)o1 +CC1CN(C(=O)C(NC(=O)c2ccc(N3CCN(C)CC3)cc2)C2CCCC2)C2C(=O)COC12 +O=C1c2c(ccc(O)c2O)CN1Cc1ccc(F)c(F)c1 +Cc1c(Cc2ccccc2)nc2cc(F)cc(F)c2c1N1CC(C)(C)c2ncc(N3CCOCC3)cc21 +O=C(Nc1cc(C2CCN(C3CCC3)CC2)nn1-c1ccc(Cl)cc1F)c1cnn2cccnc12 +Cc1ccnc(-n2nnc3c2CCN(C(=O)c2cccc(Cl)c2Cl)C3C)c1 +CC(Nc1nccc(N(CC2CCN(S(N)(=O)=O)CC2)C(=O)c2ccc3c(c2)CCO3)n1)c1ccccc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCC(F)(F)F)nc23)N1 +CCCCc1nc(C=Cc2cccc(C(CCc3ccccc3C(C)(C)O)SCC3(CC(=O)O)CC3)c2)ccc1C +Cc1ccc(C2=NC(=O)C(=Cc3cccs3)S2)cc1 +Cc1cccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)n1 +Cc1cccc(Cl)c1-c1nnc2c(C)nc3cnccc3n12 +Nc1ncc(-c2cn3c4c(nc3c(N3CCOCC3)n2)CCN(C(=O)NC2CCCCC2)C4)cn1 +N#Cc1ccc(Oc2ccc3nc(C(=O)NC4CCN(Cc5ccccc5)C4)ccc3c2)cc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2C(F)(F)F)n2c1COCC2)c1ccccc1 +Fc1ccccc1-c1cn2ccnc2c(NCc2ccncc2)n1 +O=C(O)CC(NC(=O)C(c1ccccn1)n1cccc(NC(=O)c2ccc3ccccc3c2)c1=O)C(=O)COc1ccccc1 +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cocn1 +CC(C)CCCCC(=O)NC(CO)C(=O)NC(CC(C)C)C(=O)C1(CO)CO1 +CC(=O)N1C(C)(C)C=C(c2nc3c(C(N)=O)cccc3[nH]2)C1(C)C +c1ccc2c(c1)CCCCC2CCN1CCN(c2cccc3c2OCCO3)CC1 +CCOCCOCCOc1cccc(N2CCN(CCCCc3c[nH]c4ccc(C(N)=O)cc34)CC2)c1C#N +O=C(NC(Cc1ccccc1)C(=O)O)c1ccccc1-c1ccccc1C(=O)NC(Cc1ccccc1)C(=O)O +O=C(NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1cc2ccccc2[nH]1 +O=C(NCCCCCCCNc1c2c(nc3ccccc13)CCCC2)c1cc2ccccc2oc1=O +O=C(C=Cc1cc(Cl)ccc1-n1cnnn1)NC1CCCCCNc2cc(NC(=O)OCC3CCCO3)ccc2-c2c[nH]c1n2 +CN1CCN(c2ccc(Nc3nc4c(NCc5cccc(N(C)S(C)(=O)=O)c5)cccn4n3)cc2)CC1 +FC(F)(F)c1ccccc1C1CCN(c2cc(N3CCCC3c3nc4cc(Cl)c(Cl)cc4[nH]3)ncn2)CC1 +COc1ccc(-c2nnc(C(=O)N3CC(Oc4ccc(CN5CC6(CCCO6)C5)cc4)C3)o2)cc1 +O=C(CCCNC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc21)NO +CCCc1ccc(S(=O)(=O)N2CCN(c3ncccc3C(F)(F)F)CC2)cc1 +O=S(=O)(O)OCC1CNCC(OCc2ccc3ccccc3c2)C1c1ccc(OCCCOCc2ccccc2)cc1 +O=C(CP(=O)(O)O)NCCCc1cccc(Oc2ccc(Cl)c(Cl)c2)c1 +Cc1ccc(CN(C(=O)c2ccc(O)cc2O)c2ccc(-c3nc4ccccc4cc3C)cc2)cc1 +OCCN(CCO)c1nc(N2CCc3ccccc3C2)c2nc(N(CCO)CCO)nc(N3CCc4ccccc4C3)c2n1 +Nc1ncc(-c2ccc(-c3ccc(C(F)(F)F)cc3S(N)(=O)=O)cc2F)cn1 +O=C(CC1CCCCC1)N1CCC(c2nc(-c3cccs3)no2)CC1 +Cc1cccc(Cl)c1Nc1nc2ccc(N(C)CCO)nc2n2cncc12 +CCN1CCN(Cc2nc3ccc([N+](=O)[O-])cc3c(=O)n2-c2ccccc2)CC1 +COc1ccc(CN2CCN(c3c(C)c(C)c4c(c3C)CC(C)(C)O4)CC2)cc1 +O=C(NC1CC2CCC1C2)C1(NS(=O)(=O)c2cccc(Cl)c2)CC1 +C=CC1(C)CC(=O)C2(O)C(C)(O1)C(O)C(OC(=O)NCCC(=O)OCC)C1C(C)(C)CCC(O)C12C +CNc1nn2c(OC)cc(-c3cccnc3)nc2c1S(=O)(=O)c1ccccc1 +NC(COc1cncc(-c2ccc3[nH]c(=O)oc3c2)c1)Cc1c[nH]c2ccccc12 +CCCOC(=O)C1=CN(C(=O)c2ccc(F)cc2)CCc2c1[nH]c1ccccc21 +COc1cc2[nH]c(C)c(-c3ccc(C(C)=O)cc3)c(=O)c2cc1Cl +CCOc1ccc(-c2c(C)c3cc(O)ccc3n2Cc2ccc(OCCN3CCCCCC3)cc2)cc1 +CCC(C)Oc1nc(Nc2ccc(S(N)(=O)=O)cc2)nc(N)c1C=O +CS(=O)(=O)c1cnc(OC2CCC(OC3CCN(C(=O)C4(C(F)(F)F)CC4)CC3)CC2)cn1 +CCCCCCC(=O)OCC(C)(C)CC1=C(O)C(=O)c2ccccc2C1=O +COc1ccc(F)cc1C(C)(C)CC(O)(CNc1ccc2c(c1)COC2=O)Cc1ccccc1 +CC(=C1C(=O)Nc2ccc(NC(N)=O)cc21)c1cc(CNC(=O)c2ccncc2)c[nH]1 +O=S(=O)(Nc1ncc(F)s1)c1ccc2c(-c3ccc(C(F)(F)F)cc3C3CCNCC3)cccc2c1 +Cc1ccc2c(c1)C(=Nc1ccc(C)c(N=C3C(=O)Nc4ccc(C)cc43)c1)C(=O)N2 +COc1ccc(Br)cc1N1CCN(Cc2ccc(F)cc2Cl)C(=O)C1=O +COc1ccc2cc(-c3cncc(C(C)O)c3)ccc2c1 +CC(C)Oc1cc(NC(=N)c2ccccn2)ccc1-c1ccc(-c2ccc(NC(=N)c3ccccn3)cc2OC(C)C)o1 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+CC(C)c1ccc(CNc2ccc3c(c2)ncn3-c2ccc(OCCc3ccccc3)cc2)cc1 +CN(Cc1ccc2nc(N)nc(N)c2n1)c1ccc(C(=O)C(F)(F)F)cc1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1c(-c2ccc(OC)c(OC)c2)nc2sccn12 +CCCn1c(CN2CCN(c3ncc(Cl)cn3)CC2)nc2ccccc21 +O=C(Nc1ccccc1)c1cnc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1 +Cc1cc(OCCCNCCc2c[nH]cn2)ccc1-c1nc2c(C)c(F)ccc2[nH]1 +O=c1n(Cc2ccncc2)nc(-c2ccnc(NC3CCCCC3)c2)n1-c1ccc2ccccc2c1 +COc1ccccc1NC(=O)Nc1nn(-c2ccccc2)c(=O)c2ccccc12 +CNc1nc(Nc2c(C)cc(C)cc2C)nc(NC2CCN(Cc3ccc(C#N)cc3)CC2)n1 +C=CCN1C2CCC1CC(=C(c1ccc(C(=O)NCC)cc1)c1cccc(OC)c1)C2 +COCCN1CCN(c2nc(N)c3ncnc(Nc4cc(C(=O)Nc5cc(C(C)(C)C)n[nH]5)ccc4C)c3n2)CC1 +CC(NC(=O)CC1SC(c2ccc(Cl)cc2Cl)N(CC(=O)NCCCN2CCOCC2)C1=O)c1cccc2ccccc12 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2C +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN2CCN(C)C2=O)cc1 +CCN(CC)C(=O)c1ccc(C(=Nc2ccccc2)N2CCCN(CCc3ccccc3)CC2)cc1 +NCC(c1ccc(C(F)(F)F)cc1)N1CCN(c2ncnc(N)c2OCC(F)(F)F)CC1 +Nc1ncnc2c1c(-c1ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc1)cn2C1CC(CN2CCCC2)C1 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+CCOc1ccc(OCC(=O)O)cc1CC(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C +O=C1NC(=O)c2c1c1c(ccc3cc[nH]c31)c1[nH]c3ccccc3c21 +Oc1c(Oc2cc(Cl)c(Cl)c(Cl)c2O)cc(Cl)c(Cl)c1Cl +Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnn(CC(F)F)c1N1CCC(N)CC(F)(F)C1 +O=C1NC(=O)C(=Cc2cc(-c3ccccc3)c(O)c(-c3ccccc3)c2)S1 +CCC(C)(C)c1nn(CCO)c2c1N=C(c1ccc(-n3ccnc3C)cc1)CNC2=O +CN1Cc2c(C3=CCCN(CC(=O)N4CC(O)C4)CC3)[nH]c3nccc(c23)-c2cc(F)ccc21 +CCC1C(C)C(Nc2ccccc2)c2ccccc2N1C(=O)c1ccc(Cl)cc1 +CN(Cc1ccc(F)cc1)C(=O)n1cnc(S(=O)(=O)C2CC3CCC2C3)n1 +CCN1CCN(C(=O)OC2(C3CCCC(c4cc(F)cc(F)c4)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1 +NCCCCCNC(=O)Cn1c(-c2ccc3ccccc3c2)nc2ccc(-c3ccccc3)cc2c1=O +CCN(CC)CCCNC1=C(Cl)C(=O)c2ccccc2C1=O +CC12CCC=CC1=CCC1C2CCC2(C)C(O)CCC12 +CC1CC(N)CC(c2ccncc2NC(=O)c2cccc(-c3cc(O)ccc3F)n2)C1 +N#Cc1ccc(C(NC(=O)C2CCC(N3CCOCC3)CC2c2ccc(Br)cc2)c2ccc(Cl)cc2)cc1 +CC1CC(N)CN(c2ccncc2Nc2cccc3cnc(-c4c(F)cccc4F)nc23)C1 +CCCCCc1cc2c(s1)CC1c3cc(O)c(OC)cc3CCN1C2 +CN(C)c1ccc(-c2cn(CCCCCCCCC(=O)NO)nn2)cc1 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+O=C(Nc1ccc(Cl)c(Cl)c1)Nc1cc(C(F)(F)F)ccc1Oc1ccc(Cl)cc1Cl +Cc1cc(CCC#N)cc(C)c1Oc1ccc(N)c(Nc2ccc(C#N)cc2)c1 +Cc1cc(CCC#N)cc(C)c1Nc1ccnc(Nc2ccc(C#N)cc2)n1 +O=C(CCCO[N+](=O)[O-])Oc1ccc(C(=O)Oc2ccc(-c3cc(=S)ss3)cc2)cc1Cl +CC(C)(C(=O)O)N1CCC(C(=O)NC2CCN(Cc3cccc(Oc4ccccc4Cl)c3)CC2)(c2ccccc2)C1 +CC(C)CCC1=C(C(=O)O)C(c2ccc3c(c2)OCO3)Oc2ccc(OC(C)C)cc21 +COc1ccc(NC(=O)C(=O)c2c[nH]c3ccccc23)cn1 +CC(C)(C)OC(=O)Nc1ccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)cc1 +Cc1ncc(-c2ccc3c(c2)C(=O)CC2(CCN(C(=O)c4cc(C)c5[nH]ncc5c4)CC2)O3)o1 +O=C(O)c1cc(-c2ccc(Cl)nc2)nc2c1cnn2Cc1ccncc1 +CC(O)(C(=O)Nc1ccc(C(=O)N2CCCCC2)cc1Cl)C(F)(F)F +COCCNC(=O)c1cccc(Cn2[nH]c(=O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)c1 +CC1(F)C(O)C(CO)OC1n1cc(-c2ncco2)c2c(N)ncnc21 +O=CC(Cc1ccccc1)NC(=O)c1ccccc1COc1ccccc1 +CCN(CC)CCOc1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1OC2 +Cc1ccc(S(=O)(=O)Nc2c(C(=O)NC(C)C(C)(C)C)c(C(F)(F)F)nn2-c2ccccc2)cc1 +CC(C)C(=O)N(O)C(C)c1ccc(OCc2ccccc2)cc1 +N#Cc1sc(NCCNc2nc(-c3ccc(Cl)cc3Cl)cn3nc(C(=O)NCC(=O)O)cc23)nc1N 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+Cc1cc(C)n(CCCCCC2(C)COC(c3nc(-c4ccccc4)c(-c4ccccc4)[nH]3)OC2)n1 +CCNC(=O)c1ccc(Cc2c(C(=O)OC)n(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1 +CCc1ncn(CCC(C(N)=O)(c2ccccc2)c2ccccc2)c1CC +CNC(=O)c1ncn2c1COc1c(CCN3CCN(c4cccc5nc(C)ccc45)CC3)cccc1-2 +Nc1ncnc2c1C(=O)N(c1ccc(-c3ccccc3Cl)cc1)CCO2 +CN1CCN(C(=O)c2cc3cc(Cl)cc(F)c3[nH]2)CC1 +CCCCCc1ccc(CN(CCN(CCCC)CCCC)Cc2ccc(OCc3ccccc3)cc2)cc1 +CC(C)C(=O)NC(c1nnc(CNS(N)(=O)=O)o1)c1nc2ccc(-c3ccccc3)cc2s1 +CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN5CCOCC5)cc4)c3)cc21 +CCOc1cc2ncc(C#N)c(Nc3cc(Cl)c(OCc4cccc(F)c4)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C +CC(CC(=O)O)(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +CNC(=O)C1=CC(=C2C(=O)c3ccccc3C(C)(CCC(C)(C)C)C2=O)Nc2ccc(NS(C)(=O)=O)cc21 +CC1C(O)C(Cc2ccccc2)C(=O)N1c1ccc(C#N)c(Cl)c1 +CCN1C(=O)CC2C3CCc4cc(OS(N)(=O)=O)ccc4C3CCC2(C)C1=O +O=C(Nc1ccc(C2CNCCO2)cc1)c1cnn(-c2ccc(F)cc2)n1 +Cc1csc(NC(=O)C2c3ccccc3C(=O)N(CC(C)C)C2c2cccs2)n1 +O=C(O)COCC1CCC(COC(=O)N(c2cccc(F)c2)c2ccc(Cl)c(F)c2)CC1 +CSc1ccc(NC(=O)NC(Cc2ccccc2)C(=O)N2CCCCC2)cc1 +CCc1oc(-c2ccccc2)nc1C(=O)Nc1ccc(N2CCOCC2)nc1 +O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(COC3COC3)ccc1-2 +CCc1c2c(nc3ccc(Cl)cc13)-c1cc3c(CO)cccc3c(=O)n1C2 +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccsc3)cn2CCN2CCC2)CC1 +Cc1ccc(NC(=O)c2cccn3c(=O)cc(N4CCOCC4)nc23)cc1 +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +CCOc1c(Br)cc(C2C(C(=O)OC)=CN(C)C=C2C(=O)OC)cc1OC +COc1ccc(Cc2nccc3cc(OC)c(OCCF)cc23)cc1F +COc1ccc2[nH]cc(CCNC(=O)c3cc[n+](Cc4ccc(OC(=O)N(C)C)cc4)cc3)c2c1 +CC(=O)NC(C)C#Cc1cnc(Oc2ccc(SC(C)C)cc2)s1 +CSc1sc(-c2cc[nH]n2)c2c1C(=O)NC(C(F)(F)F)C2 +O=C(C1CC1c1ccc(N2CCCC2)cc1)N1CCN(C2CCC2)CC1 +FC(F)(c1ccccc1)c1nnc(-c2sc3ccccc3c2OC2CCNCC2)o1 +O=C(c1ccc(N2CCN(C(=O)c3ccccc3Cl)CC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +COc1ccc(-n2nnnc2C(F)(F)F)cc1CNC1CCN(C(C)=O)CC1c1ccccc1 +Cc1nc(C#Cc2ccc(C3CC4CCC3C4)nc2)cs1 +CN1CC2(CCN(CC(O)Cc3ccc(Br)cc3)CC2)c2ccccc21 +O=C(NCCc1ccc(F)cc1)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CC(C)NC1=NNC(=O)C1=Cc1cc2ccccc2[nH]1 +Cc1ccccc1SC1=C(O)OC(c2ccccc2)(c2ccccc2)CC1=O +COc1ncccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +NC1CCCN(c2nc(-c3n[nH]c4cnc(-c5cccnc5)cc34)ccc2C2CC2)C1 +CC(C)=CCCn1cc(CC(P(=O)(O)O)P(=O)(O)O)nn1 +O=C1OC2(CCC(N3CCC(Cc4cc(F)ccc4F)CC3)CC2)c2ccc3c(c21)OCCO3 +COc1ccc(CCN(C)CCCOc2ccc(S(=O)(=O)c3c(C(C)C)n(C)c4ccccc34)cc2)cc1OC +CCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]ncc2c1)c1ccc(F)cc1Cl +Cc1ccc(N2CCC(F)(F)CC2)nc1C(=O)Nc1c(C)cc(C(=O)O)cc1C +Cc1ccc(-c2cc(CC(C)(C)C)[nH]n2)cc1S(=O)(=O)N1CCOCC1 +NCC1OC(OC(CNc2ccc(C3CCCCC3)cc2)C2CC(O)C(n3ccc(=O)[nH]c3=O)O2)C(O)C1O +CCn1cc(Nc2ncc(C3CC3)c(NCCCNC(=O)C3CCC3)n2)cn1 +CCN(CCO)CCOc1ccc(-c2cc3c(NCCc4ccc(NC(=O)Nc5ccccc5)cc4)ncnc3o2)cc1 +O=C(NCCCCCCS(=O)(=O)N(CCN1CCOCC1)CC1CCCCC1)Nc1ccncc1 +COc1ncc(C(CO)Nc2ncnc3c2CN(c2ccc(C)cc2C#N)CC3)cn1 +COc1ccc(-c2cn(CCCCCC(=O)NO)nn2)cc1 +COc1ccc(-c2noc(C)c2C(=O)N=C(N)NCc2cc(Cl)c(N)c(Cl)c2)cc1 +NC(Cn1c(=O)c(-c2cccc(O)c2F)cn(Cc2c(F)cccc2F)c1=O)c1ccccc1 +CC(COC(C)(C)C)Oc1ccc(S(C)(=O)=O)cc1-c1cn(C)c(=O)c2[nH]ccc12 +COc1ccc(C2=NN(Cc3ccc(CN(C)C)cc3)C(=O)C3CC=CCC23)cc1OC +CCCCCCOc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O +CC=CC=CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 +CN(c1ccc2[nH]ccc2c1)c1c(C#N)cncc1C=Cc1ccccc1 +O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2cc(Cl)ccc2c1 +N=C(N)c1cccc(C2CN(Cc3ccc(-c4ccccc4S(N)(=O)=O)cc3)CC2C(N)=O)c1 +O=C(c1ccccc1)c1ccccc1NC(Cc1ccc(OCCOc2ccc([N+](=O)[O-])cn2)cc1)C(=O)O +Cc1[nH]c2cc(S(C)(=O)=O)ccc2c1Cc1ccc(Cl)cc1 +Cn1cc(NC(=O)c2cnn3ccc(N)nc23)c(-c2cc(Cl)ccc2Cl)n1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2ccsc2)cc1Cl +[C-]#[N+]c1ccc(C2(O)CCN(C(=O)C3CCCCC3NC(=O)c3cccc(C(=O)O)c3)CC2(C)C)cc1 +CCN1CCC(CNCc2ccc(C(=O)Nc3cc(-c4ccccc4)ccc3O)cc2)CC1 +CN1CCCCC(Oc2ccc3c(c2)C(=NO)c2ccccc2-3)C1 +CCCCCCCC(C(=O)CS)C(=O)NC(CC(C)C)C(=O)Nc1ccccc1 +CC(C(=O)Nc1ccc(C2CCNC2)cc1)c1cccc(C(=O)c2ccccc2)c1 +CCNc1nc2c(SCc3ccccc3)ncnc2n1C1OC(CO)C(O)C1O +O=c1ccc(-c2ccc(S(=O)(=O)Nc3cc4c(=O)[nH]ccc4cc3F)s2)c[nH]1 +c1ccc(CNCc2ccc(CNCc3ccccc3)cc2)cc1 +COC12CCC3(CC1C(O)CCC1CCCC1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +O=C1Cc2c([nH]c3ccc(I)cc23)-c2ncccc2N1 +CC(C)(C)C(=O)Oc1ccc(Cc2ccc(OC(=O)C(C)(C)C)cc2)cc1 +COCCN1CCc2c(C(=O)N3CCC(c4ccc(F)c(F)c4C(F)(F)F)CC3)n[nH]c2C1 +COc1cc(-c2ccncc2)cc(C(C)C#Cc2c(C)nc(N)nc2N)c1 +CC(=Cc1cc(O)cc(O)c1)c1ccc(C(F)(F)F)cc1 +Cc1c(CC(=O)O)c2cc(F)ccc2n1S(=O)(=O)c1cccc(F)c1 +Cc1sc2ncnc(SCC(=O)NS(C)(=O)=O)c2c1C +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(F)c(CNCC4CC4)c3)nc2n1 +COc1cccc(-c2ocnc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 +O=C(c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1)N1CCN(c2cccc(Cl)c2Cl)CC1 +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NCCc1ccccc1 +COCC(NC(=O)Nc1cc2[nH]nc(N3CCC(OC)CC3)c2cn1)c1ccccc1 +O=P(O)(O)OCC1OC(n2cnc3c(-c4ccc(O)cc4)ncnc32)C(O)C1O +CC1(O)CCC2CCC(C(=O)NCc3ccc(C(=N)N)cc3)N2C1=O +COc1ccc2[nH]c3nc4ccnc(NCCCN(C)CCCN)c4c(C)c3c2c1 +CN(CC=CC#CC(C)(C)C)Cc1cccc(OCC(C)(C)OCc2ccsc2)c1 +CN1CCCCCNC(=O)C2=Cc3ccc(Cl)cc3-c3c(C4CCCCC4)c4ccc(cc4n3C2)C(=O)NS1(=O)=O 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+CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2ncn(CCc3ccc(F)cc3)c12 +CCCCN(C1c2cc(C(=O)NCCc3ccccc3)ccc2OC(C)(C)C1O)S(=O)(=O)c1ccc(CC)cc1 +CCOc1ccc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c(F)c1F +Nc1nnc(-c2ccc3[nH]cc(-c4cccc(N5CCOCC5)n4)c3c2)s1 +N=C(N)c1ccc2oc(C(=O)NCCC(=O)NCC(NS(=O)(=O)c3ccccc3)C(=O)O)cc2c1 +CC(C)N1CCN(C(=O)OC2CCN(c3ccc(C(F)(F)F)cn3)C2)CC1 +CC(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CS(=O)(=O)Cc1ccccc1)NC(=O)N1CCOCC1 +O=C(C(=Cc1ccc([N+](=O)[O-])cc1)S(=O)(=O)Cc1ccccc1)c1ccc(Cl)cc1 +Nc1cnc(-c2ccc(C3CCC3)c(OCc3cccc(F)c3)c2F)cn1 +COc1cccc(Nc2nnc(-c3c(NCc4ccncc4)ncn3C)o2)c1 +O=C(c1ccc(F)c(O)c1)c1nc2ccc(O)cc2s1 +COc1cccc(NC(=O)C2CC3CC3N2C(=O)Nc2cn(C(N)=O)c3ccccc23)c1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NCC2CC2)cn1 +COc1ccc(-c2c[nH]c(C(=O)c3cc(OC)c(OC)c(OC)c3)n2)cc1 +COC(=O)C(CCSC)NC(=O)C1CC(Oc2ccccc2)CN1CCCCC(N)CS +Cc1cc(C(C)(C)NC(=O)c2cccc(-c3cccc(Cl)c3)n2)on1 +CN(C)C(=O)C(=O)N(C)C1CCn2c1nc(C(=O)NCc1ccc(F)cc1)c(O)c2=O +CC(C)CC(N)C(=O)NS(=O)(=O)OCC1OC(c2nc(-c3ccc(Oc4ccccc4)cc3)cs2)C(O)C1O 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+S=C(NN=C(c1ccccn1)c1ccccn1)Nc1ccccc1 +OCC1(NCc2cccc(-c3ccc(C(F)(F)F)cc3C(F)(F)F)n2)CCCC1 +O=[N+]([O-])c1ccccc1CN1CCN(c2cc(N3CCCC3)nc(N3CCCC3)n2)CC1 +CN1Cc2c(C(=O)OC(C)(C)C)ncn2-c2ccsc2C1=O +O=C(O)C1CCC(OCC2CC(F)CN2C(=O)Cc2cc(Cl)c(Nc3nc4cc(F)ccc4s3)cc2F)CC1 +O=C(Nc1cccnc1-c1cccc(Cl)c1)c1cnn2cccnc12 +CN1C(=O)c2[nH]c(Cc3ccc(-c4ccccc4)cc3)nc2N2CC3(CCCC3)N=C12 +O=C(c1ccc(O)cc1)c1ccc(Sc2cccc(O)c2)s1 +O=C(O)CCC=CCC1COC(c2cccc(OCCOc3cc(C(=O)O)ccc3OCCn3ccnc3)c2)OC1c1ccccc1O +CCCCC(CC)CNC(=O)c1ccc2c(c1)c(Cc1ccc(C(=O)NS(=O)(=O)c3ccccc3C)cc1OC)cn2C +COc1cccc(N2CCN(C(=O)N3c4ccccc4Oc4cc(C#N)ccc43)CC2)c1 +CC1CCCC(C)N1C(=O)c1ccc(C(=C2CC3CCC(C2)N3CCc2ccccc2)c2ccccc2)cc1 +Cc1cc(C(F)(F)F)nn1-c1ccc(NCc2c(F)cccc2F)nc1 +O=S(=O)(NCCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccc2ccccc12 +CN1CCN(c2cc(-c3cccnc3)nc(-c3ccncc3)n2)CC1 +CC1(C2CCCC2)Cc2cc(OCCCCc3nn[nH]n3)c(Cl)c(Cl)c2C1=O +CC1Cc2c(nnn2-c2ncccc2F)CN1C(=O)c1cccc(C(F)(F)F)c1Cl +CNC1CCC(COCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)CC1 +CC(C)Oc1cc2c(-c3cc(N4CC(O)C(N(C)C)C4)ncn3)n[nH]c2cc1F +CCCC12CCC(C(C)=O)=C1c1c(cc(OCC(=O)O)c(Cl)c1Cl)C2 +COCC(Oc1cc(CC2C[S+]([O-])CC(NCc3cccc(C(C)(C)C)c3)C2O)cc(F)c1N)C(F)(F)F +Cc1cccc(N2CCN(CC(O)CNC(=O)c3nc(C)n(-c4cccc(Cl)c4)c3C)CC2)c1C +CCN(CC)CCCCCOc1ccc2c(=O)c3ccc(OCCCCCN(CC)CC)cc3oc2c1 +O=C(Nc1cccc(C(F)(F)F)c1)c1ccc(CO)c(-c2ccnc(N3CCOCC3)c2)c1 +c1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)c1c-2sc2ccccc12 +CC(=O)NC1CSC(=O)C(Cc2ccccc2)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(CO)NC1=O +N#CC1CC(C(=O)NC2CCC2)CCC1n1cc(C(N)=O)c(Nc2ccc(Cl)cc2)n1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1c2cc(F)c(F)cc2-c2n[nH]cc2C1C1CC1 +CNC(=O)C12CC1C(n1cnc3c(NCCc4ccccc4)nc(C#Cc4ccccc4)nc31)C(O)C2O +COc1cccc2cc(C(=O)NCCCCCCNc3c4c(nc5ccccc35)CCC4)oc12 +CCNC(=O)N1CCN(Cc2cc(Nc3nc(C)cn4c(-c5cn[nH]c5)cnc34)sn2)CC1 +O=C(CCOc1ccccc1)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +Cc1cccc(CC(Nc2ccc3c(c2)C(=O)OC3)C(=O)NC(C#N)COCc2cccc(C(=O)O)c2)c1 +COc1cc(C)nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)n1 +CCc1ccc(CNC(=O)C2CCN(C(C)c3cccc4ccccc34)CC2)cc1 +CN(C)CCCC1(c2ccc(F)cc2)OCc2c(I)cccc21 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(OC4COCCC4O)ccc3Cl)nnc12 +COc1ccc(Cc2cc(C3CCN(C(=O)c4ccc(OC)c(OC)c4)CC3)nc(N)n2)cc1 +COc1cc(-c2cc(C(=O)O)c3c(ccc4ccccc43)n2)ccc1OCCCC#N +Cc1ncc(C(CNC(=O)c2cccc(Cl)c2Cl)N2CCOCC2)cn1 +CC(C(=O)Nc1ccc(CC2=NNNN2)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 +COc1ccc(P(=O)(OCCF)N2Cc3ccccc3CC2C(=O)NO)cc1 +CC(=O)Nc1cccc(C(=O)NCC(O)CN2CCc3ccccc3C2)c1 +N#CNC(=NCc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +Cc1ccc(C)n2nc(CCc3nc(-c4cscn4)cn3C)nc12 +COc1ccccc1-c1nc(NCc2ccc(-c3cccnc3)cc2)c2ccccc2n1 +O=S(=O)(Nc1c(Cl)c(Cl)c(NS(=O)(=O)c2ccccc2)c(Cl)c1Cl)c1ccccc1 +Cc1ccc(Cl)c(CNC(=O)Cc2c(C)n[nH]c2C)c1F +Cc1ccsc1C(=CCCN1CCC=C(C(=O)O)C1)c1cccs1 +CCOC(O)=C1C(COCCn2c(C)nc(C)c2C)=NC(C)=C(C(=O)Nc2ccccc2)C1c1ccccc1Cl +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)NCCN4CCCC4)c4ccc(C)cc34)cc2)c1C +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3cccc(Cn4nnc5ccccc54)c3)n2)CC1 +Cn1nc(C(C)(C)C)c(C#N)c1-c1nc2cc(-c3ccccc3F)ncc2[nH]1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cnn(Cc4ccccc4)c3)c(C(=O)O)n1)CC2 +O=C(Nc1ccc(C2=CCN(C(=O)C3CCCO3)CC2)cc1)N1Cc2ccccc2C1 +COc1ccc(-c2ccc3c(c2)ncn3-c2ccccc2)cc1 +CC(C)C(NC(=O)Nc1ccc(C(=O)O)cc1)C(=O)N1CCCC1C(=O)NC(C(=O)C(F)(F)F)C(C)C +COc1cccc(F)c1CNC(=O)Nc1cc2[nH]nc(OC)c2c(CO)n1 +O=S(=O)(c1ccc(Cl)s1)c1cn(C2CCCNC2)c2ncccc12 +OC1CN(CCCOc2ccccc2)CCc2cc(OCc3ccccc3)ccc21 +O=C1C(=Cc2ccc(O)cc2)COc2ccc(Br)cc21 +COc1ccc(C#N)cc1-n1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +CCCCc1nc2cc(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 +COc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cccc34)c2)c(OC)n1 +CCNC(=O)Nc1nc2cc(-c3cncnc3)c(=O)n(C(C)C)c2s1 +O=C(O)c1cccc(-c2cccc(NCCNCC(O)c3cccc(Cl)c3)c2)n1 +Oc1nc2ccc(C#CCCN3CCC(Cc4ccccc4)CC3)cc2o1 +CCCSCC1c2cccc(O)c2C(=O)C2=C(O)C3(O)C(O)=C(C(N)=O)C(=O)C(N(C)C)C3C(O)C21 +O=C(CCCCCCc1ccccc1)c1ncc(-c2cccnn2)o1 +NC1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 +Cc1ccc(-c2nc(C3CCCC3)nc3c2CCNCC3)cc1 +CCCCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(CCOc3ccccc3)CC2)cc1 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+Cc1ncccc1C(C#N)N1CCN(C(=O)CC(NC(=O)OCC(C)C)c2ccccc2)CC1 +COc1ccc2c(c1)CCC1(CCCCN1CCc1c(C)cc(C)cc1C)C2=O +CCOC(=O)c1ccccc1-c1cnc(Nc2ccc(-c3cnco3)c(OC)c2)o1 +O=C(N1CCc2ncc(C(F)(F)F)cc2C1)C12CCOC1CC(NC1CCOCC1)C2 +CCn1ccc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)n1 +CC(O)CN1C(C)CN(c2ccc(Nc3ncc4cc5n(c4n3)C3(CCCCC3)CNC5=O)nc2)CC1C +O=C(NCc1cccc(OC(F)(F)F)c1)C1c2ccccc2C(=O)N1CCc1ncc(F)cn1 +CS(=O)(=O)Nc1ccc(CCNC(=O)c2ccc(O)c3nc(-c4ccc(Cl)cc4Cl)[nH]c23)cc1 +COc1ccccc1C1C(C(=O)C(C)(C)C)=C(N)C(=O)N1c1ccc(-c2ccon2)cc1 +Clc1cnc(NC2CCC(NC3CCOC3)CC2)cc1-c1nc(NCC2CCOCC2)ccc1Cl +N#Cc1cc2c(Oc3ccc(Cl)cc3OCCn3ccc(=O)[nH]c3=O)cccc2o1 +COc1ccc(NCCNC(=O)C(CC(C)C)NC(=O)c2ccc(OCc3ccccc3)cc2)cc1 +O=c1cc(NC2CCN(Cc3ccc4ocnc4c3)CC2)c2cc(Cl)ccc2o1 +COc1cc2c(cc1OC)C(=O)N1C=C(c3ccc(C(N)=O)cc3)CC1C=N2 +Cc1ccc(NC(=O)C(=O)c2c[nH]c3ccc(C)cc23)cc1 +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5ccc(F)cc5)no4)cc3)cc2)C(=O)NC(=O)NC1=O +O=C(Nc1ccc2c(c1)NC(=O)C(N1CCOCC1)C2)NC1CCC(c2ccccc2)C1 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+COc1cc(C(=O)c2sc(-c3cccc(Cl)c3)nc2N)cc(OC)c1OC +COc1nc(N)nc2c1ncn2C1OC(COP(=O)(NC2CC2)NC(C)C(=O)OCC(C)(C)C)C(O)C1(C)O +COc1ccc(C2C(=O)N(C3CCN(C(=O)n4cncn4)CC3)C2c2ccc3c(c2)OCO3)cc1 +CCOC(O)=C1C(COCCNc2cc(O)ncn2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +CN1CCC(n2ncc3ccc(NC(=O)c4ccc(F)cc4)cc32)CC1 +O=C1N(c2ccc3scc(C(F)(F)F)c3c2)CCN1c1cnccc1C1CC1 +CC(C)C(NC(=O)C(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(N)=O +CNC(=O)c1cnc(N2CCN(c3nc4cc(C(F)(F)F)ccc4[nH]3)CC2)c(Cl)c1 +CCCNC(c1cc([N+](=O)[O-])cc2nc(O)c(O)nc12)P(=O)(O)O +NC1CCS(=O)(=O)c2sc(S(N)(=O)=O)cc21 +Cc1cnc(NCC(F)(F)c2ccc(F)cc2)c(=O)n1CC(=O)NCc1cnc(N)cn1 +Fc1cccc(Nc2ccnc3cc(-c4cnn(C5CCNCC5)c4)ccc23)c1 +CCC(=O)NCCc1nc(-c2nc(C)cs2)c(-c2ccc3ncsc3c2)[nH]1 +COc1ccc2oc(Cc3c(Cl)cccc3Cl)c(CCNC(C)=O)c2c1 +CCn1nccc1Oc1cc(CC2CCC(C)(O)CC2)cnc1NC(=O)NC +O=C(Cc1ccc2ncccc2c1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccc4ncccc4c3)s2)s1 +COCCOc1cc(C=CC(=O)NS(=O)(=O)CCC(C)C)n(Cc2ccc(C(F)(F)F)cc2Cl)n1 +CNc1nc(Nc2cc3c(cc2Cl)c(C(=O)N2CC4CC2CO4)cn3C)ncc1C(F)(F)F +O=C(O)Cc1ccc(CNc2cccc(-c3c(C(=O)c4ccccc4)cnc4ccccc34)c2)cc1 +O=C(O)c1cc(-c2cc3ccccc3s2)nc2c1cnn2Cc1ccncc1 +COC(=O)c1ccc(NCc2cncn2Cc2ccc(Br)cc2)cc1-c1ccccc1 +CC(C)N1CCN(CCN2CCN(C3CC(c4ccc(F)cc4)c4cc(Br)ccc43)CC2)C1=O +CCc1ccc(CN2CCC(NC(=O)CNC(=O)c3cccc(C(F)(F)F)c3)C2)cc1 +CCCCOC(=O)Nc1ccc(S(=O)(=O)n2cc(-c3cccs3)[nH]c2=O)cc1C +O=C(O)c1ccc(-c2ccc3c(c2)CC(NCC(O)c2ccc(Cl)cc2)CC3)cc1 +CC1CCC(C(=O)Nc2cc(Oc3ccc(C(=N)N)cc3)cc(Oc3ccc(C(=N)N)cc3)c2)CC1 +Cc1cn(-c2ccc3n(c2=O)CCN(C2CCC2Oc2cccc(C(F)(F)F)c2)C3=O)cn1 +CC(C)n1cc(C2=NCC(=O)N3CCc4c(I)cccc4C3=C2)cn1 +CCCNC(=O)CCCc1nc(-c2nc(C)cs2)c(-c2ccc3c(c2)OCO3)[nH]1 +COc1ccc2c(n1)CCN(C(=O)c1cc3ncc(Br)cn3n1)CC2 +Oc1nc(O)c(-c2ccc(-c3c(C=Cc4ccc5ccccc5n4)nc4c(N5CCOCC5)ccnn34)cc2)o1 +COc1cc(-c2ccc3cc(OC)ccc3c2)cc(-c2ccc3cc(OC)ccc3c2)c1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(Nc4ccc(N5CCC(N(C)C)C5)nc4)c3c2)cc(Cl)c1O +COC(=O)N(CC(=O)O)C(=O)c1c(F)ccc2c(C(F)(F)F)c(OC)ccc12 +Cc1cc(Nc2ncc(C#N)c(Nc3ccccc3C(N)=O)n2)ccc1N1CCN(C)CC1 +C=C1C(O)C2(O)OCC34C(CC5C(C)=CC(=O)C(O)C5(C)C23)OC(=O)CC14 +CCN1CCN(C(=Nc2cccc(F)c2)c2ccc(C(=O)N(CC)CC)cc2)CC1 +O=C(NCc1cccnc1Cl)c1cncc(-c2ccc(OC(F)(F)F)cc2)n1 +COc1cnc2c(NCc3nnc4ccc(-c5ccc(=O)n(C)c5)nn34)ccnc2c1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc(C4CCNCC4)cc3)nc12 +O=C1NCc2[nH]c3c(ccc4cnc(-c5cccc(OCCN6CCOCC6)c5)cc43)c21 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCNc3ncc4ccccc4n3)c2)c1 +CCOc1ccccc1-c1nnc(SCCCN2CCN(c3ccccc3OC)CC2)s1 +CN(CCO)CCNc1ccc(NCCN(C)CCO)c2c1C(=O)c1c(O)ccc(O)c1C2=O +CCc1c(C2CCN(Cc3ccccc3)CC2)n[nH]c1-c1ccc(Cl)cc1 +CC1=C(CO)C(=O)OC(C(C)C2CCC3C4CC5OC56C(O)C=CC(=O)C6(C)C4CCC23C)C1 +COC(=O)C1CC(OC(C)=O)C(=O)C2C1(C)CCC1C(=O)OC(C(O)c3ccco3)CC12C +O=C1CC(c2ccc(CC(NS(=O)(=O)c3cccc(F)c3)c3nc4ccccc4[nH]3)cc2F)S(=O)(=O)N1 +CN(C)CCCNc1cc(-c2ccc3ccccc3c2)nc2ccccc12 +CCCCC(C(=O)O)n1c(=O)c2cnccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O +CCCCCCCCCCCCCCCCS(=O)(=O)Nc1c(OC)cc(OC)cc1OC +Cc1ccc(NC(=O)c2ccnc3[nH]c(-c4ccc(F)cc4)nc23)cn1 +NC(=O)c1nnc(NC2CCCCC2N)nc1Nc1cccc2c1ccn2C(F)F +Nc1ccc(-c2nc3ccc(-c4nc5ccccc5s4)cc3s2)cc1I +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1Nc1nc2ccccc2n1-c1cc(NCCO)ncn1 +O=C(Nc1ccc(F)cc1F)c1c(NCc2ccccc2)[nH]c(=O)n(O)c1=O +COc1ccc(C=C2SC(c3ccc(Cl)cc3)=NC2=O)c2ccccc12 +CN1CCC(n2cc(S(=O)(=O)c3ccc(F)cc3)c3cccnc32)C1 +Nc1cnc(Sc2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)cn1 +CCc1nn(C2CCCC2)c2c1CCn1c-2nnc1C1(C)CCCCC1 +CC(C)(C)OC(=O)NC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1 +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3cc(Cc4ccccc4)no3)CC2)C(c2ccccc2)C1 +CCOc1ccc(F)c(C2CC2NC(=O)Nc2cc(Cl)cnn2)c1Cl +CCCCCN1C(=O)C(=CNC23CC4CC(CC(C4)C2)C3)C(=O)c2cc(OC)cc(C)c21 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cc(-c4cccnc4)cc(-c4cccnc4)c3)o2)c1 +O=C(O)CCCOc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 +CC(C)C(NS(=O)(=O)c1ccc2oc3cc(NS(=O)(=O)c4ccccc4)ccc3c2c1)C(=O)O +O=C(NCc1ccnnc1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CC(C)CN(CCc1ccccc1)S(=O)(=O)c1ccc(N2CCN(S(C)(=O)=O)CC2)cc1F +COc1ccc2cc(S(=O)(=O)NC(CCCN=C(N)N)C(=O)N3CCC(C)CC3)cc(OC)c2c1 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+C=CC1(C)CC(=O)C2(O)C(C)(O1)C(O)C(OC(=O)NCCc1ccc(N)cc1)C1C(C)(C)CCC(O)C12C +CCOC(=O)c1nc(-c2ccc(NC(=O)Nc3ccc(N4CCOCC4=O)cc3)cc2F)nc(N2CCOCC2)c1OCC +Cc1ccc(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N(C)CCN(C)C)nc12 +O=C(NCCc1c[nH]cn1)c1ccc(-c2ccccc2)cc1 +CC(c1ccc(F)cc1)N(Cc1cccc(C(=O)O)c1)C(=O)c1cc2cc[nH]c2cn1 +Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOCC5)cc4n3Cc3ccccn3)cn12 +CC=CCN1CCC(N2CCN(c3ccccc3)CC2)C(O)C1 +COc1cccc2nc(C)n(-c3ccc(OCCCN4CCCC4)cc3)c(=O)c12 +CCC(=O)Nc1nc(C)c(-c2csc(Nc3cccc(C(C)=O)c3)n2)s1 +CCc1nn(Cc2ccc(-c3nc4ccccc4[nH]3)cc2)c(CC)c1CC(=O)O +O=C(Nc1nnc(-c2ccc3c(c2)CCCC3)o1)c1ccccc1 +COc1cc2nc(N3CCOCC3)nc(NC3CCN(C)CC3)c2cc1OC +O=C(NC(Cc1ccc(O)cc1)C(=O)O)c1cnn2c(C3CCCCC3)c(-c3ccc(F)cc3)cnc12 +CC1(N)CCC(Nc2c(C(N)=O)cnn3cc(-c4cncc(C(=O)O)c4)cc23)C1(C)C +Cc1cnc2[nH]cc(Cc3ccc(NCc4ccc(C(F)(F)F)nc4)nc3F)c2c1 +Cc1cc(CN2CCc3ccccc3C2C(=O)Nc2ccc(Cl)cc2Cl)ccc1OCC(=O)O +CC(NC1CC(CCc2nc3cc(C(C)(C)C)ccc3[nH]2)C1)C1OC(n2cnc3c(N)ncnc32)C(O)C1O 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+Cc1nn(-c2ccc3onc(N)c3c2)c2c(=O)n(-c3ccc(-c4ccccc4CN4CCC(O)C4)cc3)c(C)nc12 +CCOC(=O)N=S(C)(=O)Cc1cccc(Nc2ncc(F)c(-c3cccc4c3OCCC4)n2)c1 +Cc1ccc(-c2cc(NCC(C)O)c3ccccc3n2)cc1Cl +Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(C)c3C2=O)nc1 +COc1ccc2c(C)c(C(=O)c3cc(OC)c(OC)c(OC)c3)oc2c1 +CCN(CC)c1ccc(NC(=O)C2CCc3cccc(OC)c3C2)cc1 +COc1cccc(-n2ncc3c(NN=Cc4ccncc4)ncnc32)c1 +CC1CCC(C(C)n2c(N3CCOCC3C)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CCN1C(=Cc2sc3ccc(OC)cc3[n+]2CC)C=Cc2ccccc21 +CC(=O)c1cn(CC(=O)N2CC(F)CC2C(=O)NCc2cccc(Cl)c2F)c2cc(OC(F)(F)F)ccc12 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(-c2ccncc2)cc1 +COc1ccc2ncnc(Nc3ccc(OC4CCN(C(=O)Nc5c(F)cccc5F)CC4)c(C)c3)c2c1 +CCc1cc(-c2cc[nH]n2)c(O)cc1OCCCOc1ccccc1CC(=O)O +CCOc1ccc(N(C(=O)OCC2CCC(COCC(=O)O)CC2)c2cccc(F)c2)cc1 +Cc1ccc2oc(=O)c3cnn(CC(=O)NC4CCN(Cc5ccccc5)CC4)c3c2c1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCN(C(=O)C3CCCCC3)CC2)c1 +CCCN(C)C(=O)c1ccc2c(c1)nc(Cc1ccc(OCC)cc1)n2CC1CC1 +CC(C)C(NC(=O)OCc1ccccc1Cl)C(=O)NC(CC(=O)O)C(=O)CF +O=C(C(O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCC(N2CCCC2)CC1 +NC(CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)C(=O)N1Cc2conc2C1 +COc1ccc(N=C2c3cccc(Cl)c3C(=O)c3c(Cl)cccc32)cc1 +CC1(c2ccc(C=CC(=O)O)cc2)c2ccc(O)cc2CCN1c1ccc(CC(F)(F)F)cc1 +CN=C1CCc2c1n(C)c1ccc(OC(=O)NC)c(Cl)c21 +NC(=O)c1ccc2[nH]cc(CCCCN3CCN(c4ccc(O)cc4)CC3)c2c1 +Cc1c(Cc2ccccc2)nc(SCOCc2ccccc2)[nH]c1=O +CC(=O)Nc1ccc2c(Nc3cccc(Br)c3)ncnc2c1 +O=C(Nc1ccc(-c2nc3ccccc3s2)cc1)C1CCN(S(=O)(=O)c2cccs2)CC1 +O=C1Nc2ccccc2C1(c1c[nH]c2ccc(Br)cc12)c1c[nH]c2ccc(Br)cc12 +CN(C)c1ccc(C#Cc2ncnc(N)c2-c2ccccc2)cc1 +Cc1cc(SC2=C(O)OC(CCc3ccco3)(C(C)C)CC2=O)c(C(C)(C)C)cc1CO +CCCCc1ccc(-c2ccc(S(=O)(=O)NCCc3c[nH]c4ccccc34)cc2)cc1 +c1ccc(-c2nc(Nc3ccc4[nH]ncc4c3)c3cc(OCCN4CCOCC4)ccc3n2)cc1 +CN(C(=O)C(C)(C)C1(O)CCN(CCc2ccccc2Cl)CC1)C1CCCCC1 +O=C(CCCCCCC(=O)Nc1ccc2c(c1)C(=Cc1ccc[nH]1)C(=O)N2)NO +O=C(c1ccc(Cl)cc1Cl)N1CCCC(C(F)(F)F)C1 +COc1ccc(CN2CCN(CCCN3C(=O)c4ccccc4C3=O)CC2)cc1 +CC(=O)N1CCN2CC(C)C(C)(c3cccc(O)c3)CC2C1 +COC1CCC2(CC1)Cc1ccc(OC(F)(F)C(F)F)cc1C21N=C(N)N(C)C1=O +CC1=C2NCC3C(CCC4(C)C(C(=O)NC(c5ccccc5)c5ccccc5)CCC34)C2(C)CCC1=O +CCCN1CCC=C(c2ccc(Nc3nc(Nc4ccccc4C(N)=O)c4cc[nH]c4n3)c(F)c2)C1 +COc1ccc(C2CC(=O)N(Cc3cc(I)cc(C4(C(F)(F)F)N=N4)c3)C2)cc1OC1CCCC1 +CCNC(=O)Nc1nc2ccc(-c3ccccc3OCC)cc2s1 +CCC(=O)NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1 +CCOC(=O)c1cccc(-c2cnc(C(=O)CCc3ccc(-c4ccccc4)cc3)o2)n1 +COc1cccc(-c2cc3nc(NCCN)c4ncc(C)n4c3s2)c1 +COc1ccc(Nc2c3ccccc3nc3c(OCCCCN(CCCl)CCCl)cccc23)cc1N +CNC(=O)c1cnc(N)c2cc(-c3ccc(C(C)(C)C#N)cc3)sc12 +NS(=O)(=O)c1no[n+]([O-])c1-c1ccccc1 +COc1ccccc1N1CCN(CCN2C(=O)c3cc(I)ccc3C2c2ccccc2)CC1 +COc1c(C(=O)O)cc2c(c1CCn1cnc3c1NC=NCC3O)CCCC2 +CCC(CC)C(=O)Nc1cc(-c2ccc(OC)cc2)nc(-c2ccc(OC)cc2)n1 +CCCCC(O)C1CC(Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(C(C)=O)c1 +Cc1ncnc(C)c1C(=O)N1CC2CN(CCC(NC(=O)CC3CCCC3)c3cccc(F)c3)CC2C1 +CCC(=O)c1ccc(OCC(=O)N2CCN(CC(=O)Nc3ccc(C)cc3)CC2)cc1 +CCCCn1c(CC)c(C)cc(C(=O)NC2(C(=O)O)CCCCC2)c1=O +O=C(O)CC(NC(=O)CCC(=O)Nc1ccc2c(c1)CNC2)c1ccc2c(c1)OCO2 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2F)nc1-c1ccccc1Cl +CN1CCN2CC(c3ccc(Cl)cc3)c3ccccc3C2C1 +CNc1ccc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)cc1S(C)(=O)=O +CCC(C)Oc1ccc(CCCn2ncc3c2nc(N)n2nc(-c4ccco4)nc32)cc1 +CS(=O)(=O)c1cccc(-c2cccc3nc(Nc4ccc(CN5CCOCC5)cc4)nn23)c1 +CN(C)c1nc(N2CCC(COCCN3CCCC3)CC2)nc2scc(-c3ccccc3)c12 +O=C(Nc1ccccc1OCC(O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCCC1 +COc1ccc2c(OCC(O)CO)nc(C#N)c(-c3ccccc3)c2c1 +COc1c(C)cccc1Cc1cc2c(cc1Cl)COC21OC(CO)C(O)C(O)C1O +CC(C)(C)NCC(O)COc1ccc(-c2nc(C(F)(F)F)c[nH]2)cc1 +CCC(CO)NC(=O)Nc1cc2[nH]nc(-c3ccnc(C)c3)c2cn1 +CC1CC2OC2CC(O)C=CC(=O)Cc2cc(O)cc(O)c2C(=O)O1 +CC(C)c1cc2c(c(O)c1O)C1(C(=O)O)CCCC(C)(C)C1CC2 +CCC(C(=O)O)N1C(=O)C(=Cc2ccc(-c3cc(Cl)ccc3Cl)o2)SC1=S +O=C(O)c1ccc2c(c1)C(SCCNS(=O)(=O)c1ccc(C(F)(F)F)cc1)c1ccccc1CO2 +CN1CCc2ccc(NC(=O)c3cccc(C4CCCN4C(=O)Nc4cccc(C#N)c4)c3)cc2C1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccccc2N2N=C(c3ccccc3)NS2=O)cc1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCc1ccc2ccccc2n1 +O=C(CCN1CCCC1)Nc1ccc2nc3n(c(=O)c2c1)CCc1c-3[nH]c2ccccc12 +CCC(CC)n1cc2c3c(nc(C)nc31)N(c1ccc(C#N)cc1Cl)CC2 +COc1nn(Cc2cccc(Oc3ccccc3)c2)c(=O)o1 +COc1cc(C2CCNCC2)ccc1Nc1nc(Cc2cccc(F)c2F)n2cnnc2c1C(N)=O +Cc1noc(C)c1NS(=O)(=O)c1ccc(-c2cccc(C3CCNCC3)c2)cc1 +CCCCN(CC)c1nc(C)nc2c1nnn2-c1ccc(SC)cc1Br +COC(=O)c1ccc(Nc2nc(N(C)C)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +Cn1nc(C(F)(F)F)cc1-c1ccc(NC(=O)c2c(F)cccc2F)s1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCN(c2cncnc2)CC1 +CCCS(=O)(=O)N1CC=C(c2ccc3c(c2)CC(C2CCN(c4ncc(C5CC5)cn4)CC2)O3)CC1 +CC(C)CCc1ccc2c(NCCCNCc3ccco3)ccnc2c1 +O=C(O)C1CC2CC(Oc3cc(Cc4ccccc4)ccc3-c3nnn[nH]3)CCC2CN1 +N#Cc1ccc(Nc2nccc(OCc3cc(F)ccc3Br)n2)cc1 +Cc1cccc(-c2nc(C3CN(Cc4ccc(-c5nc6nc(C7CC7)nn6cc5-c5ccccc5)cc4)C3)n[nH]2)n1 +CC1(C2CCCC2)Cc2cc(OCc3ccc(C(=O)O)cc3)c(Cl)c(Cl)c2C1=O +CCCn1c(=O)[nH]c2[nH]c(C3CCCC3)nc2c1=O +Clc1ccc(-c2cc(N(CCCN3CCCCCC3)Cc3ccc4c(c3)OCO4)on2)cc1 +O=C(O)Cc1ccc(-c2ccc(F)c3c2CN(C(=O)OCc2ccccc2)CC3)c(OCC(F)(F)F)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1nc(-c2cccc(F)c2)no1 +CC(C)=CCCC(C)C1CCC2(C)C3CCC4C(C)(C)C(O)CCC45CC35CCC12C +Cc1cccc(N2CCN(CCCCNC(=O)c3cc4ccccc4cn3)CC2)c1 +COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(-c2ncccn2)nc1OCCO +NC(=O)C(NC(CP(=O)(O)O)NC(=O)C(Cc1ccc(O)cc1)NC(CP(=O)(O)O)NCc1ccccc1)C(N)=O +CN1C(=O)N(c2ccc(C#Cc3cccc(F)c3)nn2)C2CCCC21 +COc1cc(-c2cnn(C)c2)c(C)cc1Nc1ncc2ccnc(-c3cnn(C)c3)c2n1 +CCC(=O)OC1(C(=O)CO)CCC2C3CCC4=CC(=O)CCC4(C)C3CCC21C +Cc1cc(C)cc(Cn2c(=O)cc(N)n(Cc3ccccn3)c2=O)c1 +Cc1ccccc1C(=O)C#Cc1cn(COCCO)c(=O)[nH]c1=O +CC1CCN(C(=O)c2cccc(Nc3ccccc3Cl)n2)CC1 +O=c1cc(-c2ccc(Cl)cc2F)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1 +CN(C(=O)C(C#N)=Cc1cn(CC(=O)O)c2ccccc12)c1ccccc1 +O=C(Nc1cccc(Cl)c1)Nc1nc(CCNc2ncnc3ccsc23)cs1 +O=S1(=O)CCCN1C1CCN(C(c2ccc(Cl)cc2)c2cccnc2)CC1 +NS(=O)(=O)c1c(Cl)ccc(NC(=O)Nc2ccccc2Br)c1O +O=C(CSc1ccccc1)NCCN1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CCN(CC)CCOc1cc(-c2nc(N)nc3sc(C(=O)NCC(F)(F)F)cc23)c(Cl)cc1Cl +Cc1ccc2c(c1)C(=NNC(=O)CCCN)c1ccccc1C2=O 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+O=P(O)(O)CNC(Cc1ccc2c(c1)Cc1ccccc1-2)c1nnn[nH]1 +CC(C)Cn1c2ccc(Nc3nccc(C(F)(F)F)n3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +CN=C1N(C)CC(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCC(C)(C)CC3)c2)CN1C +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(NCC4CC4)c3Cl)C2)cc1 +CCc1c(Sc2cc(C)cc(C)c2)n(CCC2=CCCC2)c(=O)[nH]c1=O +COc1cccc(C(=O)N2CCn3c(-c4nc(C)ns4)nnc3C2C)c1 +CCC(C)C(=O)c1c[nH]c(C(Cc2ccccc2)CC(O)C(Cc2ccccc2)NC(=O)OC(C)(C)C)n1 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3cccc(OC)c3O)cc21 +COc1ncc(F)c(Nc2[nH]nc3c2CN(C(=O)OC(CN(C)C)c2ccccc2)C3(C)C)n1 +Cn1cc(NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)c(C(=O)N2CCC2)n1 +C#CCN(Cc1cc2c(O)nc(C)nc2cc1C)c1ccc(C(=O)NC(CCSc2nn[nH]n2)C(=O)O)c(F)c1 +COc1cccc(C(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c1 +CC(O)(C#Cc1cc2c(cc1F)OCCn1c-2nc(C(N)=O)c1C1CC1)CO +Cc1nc2ccccc2n1Cc1nnc(Nc2ccc(Br)cc2)s1 +O=C(NCCNC(=O)c1ccc(-c2ccccc2)cc1)c1ccc(OC2C3CC4CC2CC(C(=O)O)(C4)C3)cc1 +COc1ccc2c(c1)CCC1N=C(NCC3CCC(CNS(=O)(=O)c4ccccc4)CC3)CC21 +Cc1cc([N+](=O)[O-])cc(C)c1NC1=NCCN1 +COc1ccc(CC(C)(C)NCC(O)COc2cccc(Cl)c2Cl)cc1 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+COc1ccccc1N1CCN(CCCCNC(=O)c2sccc2C)CC1 +O=C(CSc1nc2ccc(N3C(=O)c4ccccc4C3=O)cc2s1)Nc1cccc(Cl)c1 +CNC1CCN(C(=O)c2cc3cccc(F)c3[nH]2)C1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3cccc(Cl)c3)c(C(=O)c3ccc(Cl)cc3)s2)cc1 +COc1ccc(C(=O)Nc2ccc(-c3ccc(OC4CCN(C)CC4)cc3)cc2)cc1-c1ccc(Cl)cc1 +COc1ccc(-c2c(C(=O)NC3CCN(Cc4ccncc4)CC3)noc2-c2cc(Cl)c(O)cc2O)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)c2nnn(Cc3ccccc3Br)c2C)CC1 +CN1Cc2ccc(NC(=O)NC3CC(CF)(CF)Oc4c3ccc(Cl)c4F)cc2NC1=O +Cc1ncccc1Oc1ncc(C#N)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +Cn1cc(-c2cc(C(=O)NCC(C)(C)O)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +C=Cc1nn(Cc2cc3cccc(C)c3c(=O)n2-c2ccccc2)c2ncnc(N)c12 +CCCCC(NC(=O)C1Cc2ccccc2CN1S(=O)(=O)c1ccc(OC)c(OC)c1)C(=O)O +CC(C)Nc1ccc(-c2ccccc2)c(CC(=O)NCc2ccc(C(=N)N)cc2)c1F +O=C(c1ccc(Oc2ccc(Cl)cc2O)c(Cl)c1)N1CCOCC1 +O=C(c1ccc(N2CCN(C(=O)c3ccccc3O)CC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +O=C(c1ccccn1)C1CC(Oc2ncccc2C2CCOCC2)C1 +Cc1cccc2cc(Cn3nc(C=C4SC(=O)NC4=O)c4c(N)ncnc43)n(-c3ccccc3F)c(=O)c12 +CCCc1c(OCCCSc2ccc(CC(=O)O)cc2Cl)ccc2c(C(F)(F)F)noc12 +CCOc1ccc(-n2c(C)c3c(C)nnc(-c4ccc(Cl)cc4)c3c2C)cc1 +C=C(C)C(=O)N(CCCCN=c1c2ccccc2nc2n1CCCCCC2)CCCN=c1c2ccccc2nc2n1CCCCCC2 +NC1=NC(CCc2ccc(Nc3nccc(C(F)(F)F)n3)cc2)CO1 +Nc1ccc(-c2ccc3ncc4ncc(=O)n(C5CCN(C=O)CC5)c4c3c2)cn1 +Cc1ccc2oc(=O)n(C(=O)NCCCCc3ccccc3)c2c1 +CCCc1c(OCCCCOc2ccc(C=CC(=O)O)cc2)ccc2c(-c3ccccc3)noc12 +CCOC(O)=C1C(COCCN2CC(=O)NC2=O)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +COc1ccc(C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O +COc1ccc(CNCCCCc2cn(-c3ccc(F)cc3)c3ccccc23)cc1OC +Fc1ccc2nnc(-c3ccc4cccc(OC5CCNCC5F)c4n3)n2c1 +CCCN(CCC)C(=O)Cn1c2nc3ccccc3c(C)c2c(=O)n1-c1ccc(F)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(NCC4CCCCO4)c3Cl)C2)cc1 +Cn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2-c2ccc(C(F)(F)F)cc2)CC1 +Cn1nc(N2CCCC2)nc1CCc1nc2cc(C(F)(F)F)ccn2n1 +NC(=O)c1nn(CC(=O)N2C(C(=O)NCC3CC3(Cl)Cl)CC3CC32)c2cc(F)c(F)cc12 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1Nc1cnn(-c2ncc(F)cn2)c1 +C[S+]([O-])c1ccc(-n2cnc(-c3ccc(F)cc3)c2-c2ccncc2)cc1 +Cc1cn(CCCn2c(=S)[nH]c3ccccc3c2=O)cn1 +Cc1ccccc1CN(CCN(Cc1cncn1C)c1ccc(-c2ccccc2)cc1)S(=O)(=O)c1cn(C)cn1 +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(F)cn5)cc4=O)cc31)CN1CCC2CC1 +CC(Nc1ncnc(N)c1C#Cc1cccc(CO)n1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +O=C(NO)C1(S(=O)(=O)c2ccc(OCCCc3nc(-c4ccc(OC(F)(F)F)cc4)no3)cc2)CCOCC1 +CC(C)C(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1 +c1ccc2c(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)[nH]nc2c1 +COc1cccc2c1CCc1cc(Nc3ccc(F)cc3F)ccc1C2=O +CC(C)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(C(=O)O)cc3)cc(Oc3ccc(F)cc3F)c2)CC1 +CCCC(=O)c1cnc2c(OCCCN(C)CCCc3ccccc3)cccc2c1Nc1ccccc1C +CCN(CC)C(=O)c1nc(C2CCCCN2C(=O)COc2ccccc2)no1 +CCNC(=NC#N)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +O=C1c2ccccc2C(=O)N1CCOC(=S)N(C(=O)c1ccc(Cl)nc1)c1ccc(Cl)cc1 +COC(=O)CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(C)C(C)C)c2)[nH]1 +CC(C(=O)Nc1ccc(C(=O)O)cc1)n1cc(OC(F)F)c(-c2cc(Cl)ccc2C#N)cc1=O +CCCCCCN(C(=O)c1cc2cc(O)ccc2n1C)c1ccccc1 +CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(NC(=N)N)cc2)cc1 +O=C(c1ccc(Nc2nc3ccccc3n3nnnc23)cc1)N1CCNCC1 +COc1ccc(OC)c(S(=O)(=O)NC2CCC(N3CCN(c4ccccc4OC(C)C)CC3)CC2)c1 +NC(=O)CCNC(=O)C1C(C(=O)NCc2ccc(Br)cc2)C2C=CC1C21CC1 +O=S(=O)(c1cccc(F)c1)c1ccc2c3c(oc2c1)C1(CCOCC1)NCC3 +COc1cc(Cl)ncc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +O=C1CCc2cc(C=CC(=O)N3CCC(O)(c4ccccc4)CC3)cnc2N1 +CC(=O)n1ccc2cc(-n3c(O)nnc3-c3cc(C(C)C)c(O)cc3O)ccc21 +Cc1nc(Nc2ccccc2)c2[nH]c(-c3ccccc3)cc2n1 +CC1CCC2C(C)C(OCCN(C)Cc3no[n+]([O-])c3C#N)OC3OC4(C)CCC1C32OO4 +Cc1cc(NC(=O)C2(F)CCNCC2)nn1Cc1cc(Cl)cc2cc(-c3ccccc3)oc12 +COc1ccc(NC2=C(N3CCCCC3)C(=O)c3ccccc3C2=O)cc1 +C#CCN1CCc2nc3nc(N4CCCCC4)c(C#N)cc3c(N)c2C1 +Cc1ccc(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)cc1 +Cc1nc2c(s1)C(c1cc(Cl)ccc1OCC(=O)O)N(C(=O)C1CC1c1ccccc1)CC2 +CC1(c2ccc(OCCN3CCCC3)cc2)c2ccc(O)cc2CCN1c1ccccc1 +CC(C)(C(=O)NC1C2CC3CC1CC(C(N)=O)(C3)C2)c1ccc(C#N)cn1 +COC(=O)NCc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1 +CC(C)(C)OC(=O)NCCCCCCCNC1CCN(CCc2ccccc2)CC1 +CCc1cn(-c2nc(NC)c3ncn(C4OC(CO)C(O)C4O)c3n2)nn1 +CN(C)C(=O)c1cc(CN(CCC#N)c2cc(F)cc(F)c2)c2oc(N3CCOCC3)cc(=O)c2c1 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+COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cn1ccc2ccc(C(=O)NCC3CCCC3)cc21 +Cc1c(C)c(CCO)c(C)c(C(CCCCCC(=O)O)c2ccc(F)cc2)c1O +CC=Cc1sc(-c2nccs2)nc1C(=O)NCCCNC(=O)CS +O=S(=O)(NCCCCN1CCc2ccccc2C1)c1ccccc1 +O=C(Nc1ncc(CCNc2ncnc3ccsc23)s1)Nc1ccccc1Cl +O=C(CCCn1cnc([N+](=O)[O-])n1)Nc1ccc(F)c(Cl)c1 +CC(C)(C)N1CCC(Oc2cc(-c3ccc(F)cc3F)c3ccc(=O)n(-c4c(F)cccc4F)c3c2)CC1 +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)n1cc(-c2cnn3ccc(Cl)nc23)cn1 +COc1ccc(C(=O)Nc2ccc(OCCCN(C)C)cc2)cc1Nc1nccc(-c2cccnc2)n1 +O=C(CCN1CCC(N2CCCC2)CC1)N1CCc2c(nc(O)c3ccccc23)C1 +COc1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)c2)cc1 +COc1ccc(Nc2nc3cc([N+](=O)[O-])cc([N+](=O)[O-])c3nc2-c2ccccc2)cc1 +CC(c1ccccc1)c1nnc(-c2sc3ccccc3c2OC2CCNCC2)o1 +CC(C)c1ccc(S(=O)(=O)n2cc(CN3CCN(C)CC3)c3c(Cl)cccc32)cc1 +O=C(c1ccc2nc[nH]c2c1)N1CCCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1 +CN1CCCC(COC(=O)C(C)(c2ccccc2)c2ccccc2)C1 +Cc1ncnc(N2CCN(C)CC2)c1C#Cc1ccc(N)nc1 +CCn1c(C)nc(Cl)c1-c1noc(C2CCCCN2C(=O)COc2ccccc2)n1 +NS(=O)(=O)c1ccc(CNC(=O)Cc2cccs2)cc1 +CCCCc1nnc(SC(C)(C)C)n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1cc2c(cc1OC)-c1n[nH]c(-c3ccc(C(F)(F)F)nc3)c1C2 +CCOC(=O)CN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +O=C(N1CCN(C(c2ccccc2)c2ccccc2)CC1)n1nnc2ncccc21 +NC(=O)c1nc(N2CCCC(NC(=O)N3Cc4ccccc4C3)C2)sc1Nc1ccccn1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1nnccc1C(=O)O +CC(C)CC(=O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CN)CC1 +CNC(=O)c1cccc(Nc2nccc(Oc3ccc4c(C(=O)Nc5ccccc5)cccc4c3)n2)c1 +Oc1ccc(-c2[nH]c3ccccc3c2C=NNc2ccccc2)cc1 +CC(=NOCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)c(F)c1 +O=c1cc(OCc2ccccc2)c2ccc3ccccc3c2[nH]1 +CN1Cc2ccc(NC(=O)NC3CC4(CCCC4)Oc4ccccc43)cc2NC1=O +NC(=O)C(Cc1ccccc1)NC(=O)CC(Cc1ccccc1)NC(=O)C1CCCN1C(=O)C(N)Cc1ccc(O)cc1 +CN1CCN(c2ccc(-c3ccc4[nH]c5nccc(C=Cc6ccccc6)c5c4c3)cn2)CC1 +CSC1=C(c2ccc(O)cc2)C(=O)c2cc(O)cc(O)c21 +N#Cc1cccc(S(=O)(=O)N2CCCc3ccc(Oc4cc(-c5nc(C6CC6)no5)cc(Cl)n4)cc32)c1 +COc1ccc(-c2cc(-c3ccc(S(C)(=O)=O)cc3)c(-c3ccncc3)c(=O)o2)cc1 +CNC(=O)COc1cccc(Nc2ncc(F)c(Nc3ccc(C)c(Cl)c3)n2)c1 +O=C(C1CCN(c2nnc(-n3cccc3)s2)CC1)N1CCN(c2cccc(C(F)(F)F)c2)CC1 +Cc1nc2cnc(Nc3ccnc(N4CCC(O)CC4)n3)cc2n1C(C)C +c1ccc2c(-c3cncc(-c4ccsc4)c3)c[nH]c2c1 +CC1=NC(C)=C(C(=O)O)C(c2ccoc2)C1=C(O)OCC=Cc1ccccc1 +Cc1nc(C(=O)O)c2c(n1)N(Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)CC2 +Cc1nc2c(NC3CCc4ccccc43)cc(-n3ccccc3=O)cn2c1C +O=C(c1ccc2nc[nH]c2c1)N1CCCC2c3ccccc3CCC21 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)C(F)(F)F +Cc1cccc(N2CCC(C(=O)Nc3ccc4c(c3)NC(=O)CO4)CC2)c1 +COc1cccc(-c2cc3nc(-c4ccccc4)c(C)c(N4CCN(C(=O)c5ccoc5)CC4)n3n2)c1 +CC1(c2cc(Br)cc(NC(=O)c3ccco3)c2)CCSC(N)=N1 +COc1cccc2c(S(=O)(=O)NC(CCCN=C(N)N)C(=O)N3CCC(C)CC3)cccc12 +Cc1c(CC(=O)O)c(-c2ccccc2)nn1Cc1ccc(NC(=O)c2ccc3ccccc3c2)cc1 +O=C(Nc1ccc(Oc2ccc(F)cc2)cc1)C1CC(Cc2ccccc2)CN1C(=O)Cn1cncn1 +CC1(C)CC=C(c2cc(C3(O)CCS(=O)(=O)CC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +O=C(Nc1nc(-c2ccccc2)cs1)C1CCCN1C(=O)C(NC(=S)Nc1cccnc1)c1ccccc1 +CN(c1ccccc1)C1CCN(CCCOc2ccc(F)cc2)CC1 +O=S1(=O)NCc2ccccc2N1C1CCN(C2CCC3CCCCC3C2)CC1 +O=C(c1ccco1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21 +Cc1cccc(Cl)c1Nc1nc2cc(N(C)CCN3CCOCC3)ncc2n2cncc12 +COc1cc2nccc(Oc3ccc4c(C(=O)Nc5ccc(C(C)(C)C)cc5)cccc4c3)c2cc1OC +Cc1nc2cnc3cc(F)c(-c4ccc(Oc5nccc(F)n5)cc4Cl)cc3c2n1C1CCN(C(=O)CO)CC1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cc(C)cc(C)c2)c1 +CC(Nc1ncnc(N)c1C#Cc1ccc(F)cn1)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(C#N)c1 +Cc1cccc(S(=O)(=O)NCc2ccc(C(=O)NCCN(Cc3ccccc3)C(C)C)cc2)c1 +O=C(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1cc2ccccc2n1Cc1cccc(OCc2ccccc2)c1 +COc1cc(-c2cccc(C(F)(F)F)c2)c(C#N)cc1-c1nccc2cc(S(=O)(=O)Nc3ccon3)ccc12 +CCCc1nc2c(C)cc(C(=O)NC(COC)c3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCOc1cc(C=Cc2ccc(OC)c(O)c2)cc(OCC)c1OCC +Cc1c(C)c(O)c(C(CCCCCC(=O)O)c2ccc(F)cc2)c(C)c1O +COc1ccc(CN2CC3(CCN(CCc4c[nH]c5ccc(F)cc45)CC3)OC2=O)cc1 +CN(C)c1ccc(-c2nc3cc(OCCOCCOCCF)ccc3o2)cc1 +COc1cnc(C(=O)Nc2ccc(F)c(C3(C(F)F)COCC(N)=N3)c2)c(C)n1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NCc4ccccc4-n4ccnc4)nc23)N1 +CCC(CC)OC1C=C(C(=O)O)CC(NC(=N)NC(=O)CC(C)C)C1NC(C)=O +COc1ccccc1OC(=O)N1c2ccccc2Sc2ccccc21 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+COC1COCCC1NC1CCC(Cc2cccnc2)(C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)C1 +O=C(OC1CCOC1)N1CCC(CS(=O)(=O)N2CCC(c3ccccc3)CC2)(C(=O)NO)CC1 +CC(C)c1nc(C(=O)NC2CCN(CC(C)(C)O)CC2)c2ccccn12 +Cc1cc(Cc2ccc(Cl)c(Oc3cc(Cl)cc(C#N)c3)c2F)n[nH]c1=O +O=C(C1CC1c1ccc(C(F)(F)F)cc1)N1CCN(S(=O)(=O)c2cc(O)cc(C(F)(F)F)c2)CC1 +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccc(Cl)c(F)c3)sc12 +CC1CC(Nc2nc(N3CCOCC3)[nH]c(=O)c2-c2ccc3ccccc3n2)C(O)C1O +c1ccc2c(OCC3CCCN3c3ccnc4ncnn34)cncc2c1 +O=C(c1cn(CC(F)(F)F)cn1)N1CCC(O)(c2ccccc2)C2CCCCC21 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(C#CC(C)(C)C)c2)c1 +C#CCN(Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)c1ccc2nc(N)nc(N)c2c1 +O=C1OC(CO)(COC(=O)C(c2ccccc2)c2ccccc2)CC1=Cc1ccc(-c2ccc(C(F)(F)F)cc2)cc1 +CCc1ncnc(-c2ccc(C(=O)N3CCC(N(C)C)C3)c(C)c2)c1C#Cc1ccc(N)nc1 +COCCNC(=O)c1cccc(Nc2ncc3cc(-c4ccncc4)ccc3n2)c1 +O=C(NCC1CCNCC1F)c1c(F)cccc1-c1cccc(Cl)c1 +Cc1c2ccccc2nc2c1c(=O)n(-c1ccc(F)cc1)n2CC(=O)N(C)c1ccc(Cl)cc1 +CSCCC(NC(=O)c1ccc(COCc2ccc(-c3ccc(F)cc3)o2)cc1-c1ccccc1C)C(=O)O 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+CCCCOc1cc2c(cc1C(=C1CC1)c1ccc(C(=O)O)cn1)C(C)(C)CCC2(C)C +CCc1ccccc1Nc1nccc(-c2c[nH]c3ncccc23)n1 +O=C(NC1CCN(C(=O)c2ccccn2)CC1)NC12CC3CC(CC(C3)C1)C2 +Cc1ccccc1C(C(=O)NC1CCCCC1)N(C(=O)CNc1ccccc1)c1cccc(F)c1 +OC1CC2(n3cnc4c(NCc5ccccc5OCCF)nc(Cl)nc43)CC2C1O +COc1cccc(CN2CC(=O)N(c3cnn(Cc4c(C)noc4C)c3)C2=O)n1 +O=C(O)c1ccnc2cc(C(OCC3CCC(F)(F)CC3)c3ccccc3Cl)[nH]c12 +FC(F)(F)c1cccc(-c2ccc3nnc(CCl)n3n2)c1 +CCNc1n[nH]c2cc(NC(=O)NC3COc4ccccc4C3)ncc12 +Cn1nc(S(N)(=O)=O)sc1=NSC(=S)N1CCOCC1 +CC(C)(C)C(=O)CN(CCNc1ccnc2cc(Cl)ccc12)C(=O)c1cnccn1 +COCC(C)Oc1nc(C2CCCO2)c(C(=O)NC2C3CC4CC2CC(O)(C4)C3)s1 +O=C(c1ccc(C2=NCCN2)cc1)N1CCN(S(=O)(=O)c2ccc3cc(Br)ccc3c2)CC1 +Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccncc3N(C)C2=O)c1 +c1ccc2c(NCCCNc3c4c(nc5ccccc35)CCCC4)c3c(nc2c1)CCCC3 +NC1=NC2(CCOC1)c1cc(-c3cccnc3F)ccc1Oc1cnc(C3CCC(F)(F)C3)cc12 +CC1CC2(Cc3ccc(C#N)cc3C23N=C(N)N(CCc2ccncc2)C3=O)CC(C)C1O +CCCCN(C)C(=O)Cn1c2nc3ccccc3c(C)c2c(=O)n1-c1ccc(Cl)cc1 +CC(=NNc1ncnc2sc3c(c12)CCCC3)c1ccc2ccccc2n1 +COc1ccc(C(=O)NC(CNCc2ccc(C(=O)Nc3ccccc3N)cc2)Cc2c[nH]c3ccccc23)cc1 +Cc1ccc(Nc2c(Cl)cc(Cl)cc2Cl)c(CC(=O)O)c1 +NC(CNc1nc(-c2ccncc2)nc2c(C3CC3)csc12)Cc1ccccc1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCn1ncnn1 +COc1ccccc1C(=O)NCC1(c2ccc(Cl)cc2)CCOCC1 +COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3F)c2cc1OC +Cc1nnc2ccc(-c3cccc(C(F)(F)F)c3)nn12 +CN(C)CCc1cc(-c2ccncc2)c(-c2ccc(F)cc2)[nH]1 +CNC(=O)C(Cc1ccc2ccccc2c1)N1CCC(=O)N(Cc2ccc(O)c(OC)c2)C(CC(C)C)C1=O +C=Cc1ccc2c(c1)C(=O)N1CCCC1c1c(C(=O)OC(C)(C)C)ncn1-2 +N=C(N)c1cccc(-c2cc(-c3cc(C(=N)N)ccn3)no2)c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(S(N)(=O)=O)CC4)cc3OC)ncc2C(F)(F)F)c1 +CC(Nc1cc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)c1cccc(F)c1 +COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)c[nH]c2=O)C3=O)c(OC)n1 +O=C1NC(=O)c2ccc(I)cc2C1=CNCc1ccc(-c2cccnc2)c(O)c1 +CC1CN(S(=O)(=O)CC2CCC(N(C)c3ncnc4[nH]ccc34)CC2)CCN1C +Cc1nc(-c2cn3c(n2)-c2ccc(N4CCCC4CN4CCCC4)cc2OCC3)n(C(C)C)n1 +O=C(NCCC(c1ccc(F)cc1)c1ccc(F)cc1)c1cccnc1 +Cc1ncc([N+](=O)[O-])n1CCOC(c1ccccc1)c1ccccc1Cl +CC(C)(C)CC1NC(C(=O)NC2CCC(O)CC2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(F)ccc12 +O=[N+]([O-])c1ccccc1S(=O)(=O)NCC1CCC(CNCc2ccc3ccccc3n2)CC1 +O=C(NCC1CCOCC1)c1cnc(Nc2ccc(Cl)cc2Cl)cc1C1CCCC1 +COc1ccc(CNc2ncnc3c(CCO)c(OC)c(N(C)C(=O)C(C)C)cc23)cc1Cl +CC(=O)NC1=NN(C(C)=O)C(c2ccc(Br)cc2)S1 +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(OCCN)ccc3N2)c(O)c2cccnc21 +C=CCC(O)(CC=C)c1ccc(OCCCN2CCCCC2)cc1 +CN(C)c1ccc2c(c1)C(C#CC1CC1)(C(F)(F)F)OC(=O)N2 +COc1cc(C(C)=O)ccc1SCCCN1CCC(c2noc3cc(F)ccc23)CC1 +COc1cc2ncnc(Oc3ccc(NC(=O)Nc4ccc(C)cc4)cc3)c2cc1OC +CC1OC(=O)C2CC3COCCC3C(C=Cc3ccc(-c4cccc(C(F)(F)F)c4)cn3)C12 +Cc1c(S(=O)(=O)Nc2ccc(C(=O)NCC(=O)O)cc2S(C)(=O)=O)sc2ccc(F)cc12 +CNc1ncnc2c1ncn2C1OC(COP(=O)(O)O)CC1OP(=O)(O)O +CC(C)n1c2ccc(C(=O)c3cccs3)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +Cc1cc(Cl)ccc1C1c2c(nn(-c3cccc(C#N)c3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F +COC(=O)c1ccc(F)cc1CS(=O)(=O)Nc1ccc(C)n(CC(=O)NC(CCCN=C(N)N)C(=O)O)c1=O +Cc1cccc(C)c1-c1noc(C)c1NC(=O)NCc1ccc(OC(C)C)nc1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1cc(Cl)c(Cl)cc1F +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NC1CC(F)(F)C1 +COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccccc2)cc1 +CCCN(C(=O)c1ccccc1)C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1 +CN(C)Cc1cc(CC(N)=O)ccc1Oc1ccc(Cl)c(Cl)c1 +Cc1cnnc(N2CCN(C(=O)Nc3ccc(C(C)(C)C)cc3)CC2)c1 +CC(CO)OCC(Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccc(C#N)cn1 +COc1ccc(Cn2c(CC(C)(C)C(=O)O)c3c4c(c(OCc5ccc(-c6ccccc6)cn5)ccc42)CC(C)S3)cc1 +FC(F)(F)c1ccc(Nc2nc(N3C4CCC3CC4)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccsc3)n(CC(=O)N3CCC(N4CCCC4)CC3)c2c1 +CSc1ccc(Cn2c(CC(C)(C)CC(=O)O)nc3cc(Cl)cnc32)cc1 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccn2cncc2c1 +COc1cccc2c1Cc1c(Nc3ccc4c(c3)OCCO4)n[nH]c1-2 +COc1c(OCC(O)CN2CCC2)ccc2c1N=C(NC(=O)c1cccnc1C)N1CCN=C21 +CN(C)Cc1ccc2c(c1)CN(C(=O)Nc1ccc(-c3n[nH]c(=O)c4ccccc34)cc1)C2 +O=C(O)CCc1ccc(OCc2ccc(CN3CCC4(CC3)CC(Cc3ccccc3F)CCO4)cc2)cc1 +O=C(NC1CCN(Cc2ccccc2)C1)c1cccc(-c2ccccc2)c1 +CCCn1ccc(=O)c2c(N)nc(-c3ccccc3)cc21 +CC(Nc1ncnc2ccc(OCCCCCCC(=O)NO)cc12)c1ccccc1 +COC1(c2ccccc2)CCCN(S(=O)(=O)c2ccc(C(C)(C)C)cc2)CC1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1NC(c1ccccc1)CC2c1ccccc1 +Cn1nc(-c2ccc(C(N)=O)cc2)sc1=NC1CCC(O)CC1 +CCc1ccnc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC4CCCN4CC2C)C3(C)C)c1 +Cc1ccoc1C(=O)Nc1ccc(F)c(-c2nc3ncccc3o2)c1 +Cc1cncc(C(=O)Nc2cccc(CN3CCC(C)(C(=O)NC4CCCCC4)CC3)c2)c1 +COc1ccc(C(=O)ON=C(N)Cc2ccc(Cl)cc2)c(OC)c1 +O=C1NC(=O)c2c1c1c3ccccc3[nH]c1c1c2c2cccc3c2n1CCC3CO +Cc1csc(NC(=O)c2cc(Sc3nccn3C)c(F)cc2N)n1 +CNCC(O)C(c1cccc(OC)c1)n1ccc2ccccc21 +O=[N+]([O-])c1cn2c(n1)OCC(OCc1cccnc1-c1ccc(OC(F)(F)F)cc1)C2 +O=[N+]([O-])c1ccc(CCNCC(O)COc2cccc3[nH]ccc23)cc1 +COc1cccc(CCCCCCc2cccc(OC)[n+]2C)[n+]1C +O=C(c1nn(-c2ccc(CN3CCOCC3)cc2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +O=C(CC1Sc2ccccc2N(CC(=O)N2CCCC2)C1=O)NO +C=C(CC)C(=O)c1ccc(OCC(=O)OCCc2ccc(O)cc2)c(Cl)c1Cl +Cc1cc(-c2ccccc2)cc(C)[n+]1CCc1ccc(S(N)(=O)=O)cc1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(NCc4ccccn4)n3)cccc2s1 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+CCCCCCN(CCCCCC)C(=O)C(=O)c1c(-c2ccc(OC)cc2)[nH]c2ccccc12 +CCNC(=S)NNC(=O)CSc1nc2sc(C(=O)OCC)c(C)c2c(=O)n1CC +O=C(O)CCCC1(c2ccccc2)CCCN(C(=O)Nc2ccc(Cl)cc2)C1 +CCOC(=O)C1=C(C)Nc2nc3c(c(N)c2C1c1ccc([N+](=O)[O-])cc1)CCCC3 +N#Cc1cccc(Cn2cc(NC(=O)c3n[nH]c4cc(-c5cn[nH]c5)ccc34)cn2)c1 +CCCCc1ccc(-c2nnc(-c3ccccc3C(F)(F)F)n2C)c(C)c1 +COc1ccc2c(c1)CCCC2CCCCN1CCCC(C)(C)C1 +Cc1ccc(CN2CCN(CC(=O)C(O)(c3ccccc3)C3CCC3)CC2)cc1 +Brc1ccc2c3c(cccc13)-c1nc3ccccc3nc1-2 +CC(C)CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C +CC(Nc1ncnc(N)c1C#N)c1nn2ccc(C(F)(F)F)c2c(=O)n1-c1ccccc1 +CN(C)C(=O)CN(C)C(=O)Cn1c(-c2ccc(Cl)cc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CN(Cc1ccccc1)Cc1c[nH]c(-c2cccc(F)c2)n1 +COc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Sc2ccccc2C)CC1 +Cc1ccc(F)cc1C1NC(=O)C=C(c2cccc(Cl)c2)C12C(=O)Nc1cc(Cl)ccc12 +Cn1cc(-c2ccc3nc(NC(=O)c4cccc(F)c4)cn3n2)c(-c2ccc(F)cc2)n1 +CCCn1c(=O)c2nc(C3C(C)(C)CCC3(C)C)[nH]c2n(CCC)c1=O +Cc1[nH]c2nc(N)[nH]c(=O)c2c1Sc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(F)c1 +Cc1ccc(C2CC3CCC(C2c2ccc(C)cc2)N3C)cc1 +Cn1cc(-c2ccc3c(c2)CCC3=NO)c(-c2ccncc2)n1 +FC(F)(F)c1cnc(Nc2ccc(C3CNCCO3)c(Cl)c2)nc1 +O=C(O)c1ccc(Oc2ccc(CN3CCC(N4C(=O)N(C5CCOCC5)CC4c4cccc(Cl)c4)CC3)cn2)cc1 +CS(=O)(=O)c1ccc(-c2nc(-c3ccccc3)sc2-c2ccc(F)cc2)cc1 +Cn1cnc2cc(-c3ccc(N4CCNCC4)cc3)nc(NCCO)c2c1=O +Cn1c(-c2ccc3nccnc3c2)c(-c2ccoc2)c(=O)n1C +CN(C)CCCNC(=O)CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1 +Oc1cc(NCCCNCc2cccc(Cl)c2Cl)nc2ccccc12 +CC(C)Nc1nc(NC(=O)Nc2ccccc2)n2nc(-c3ccco3)nc2n1 +CC1(C)CC=C(c2cc(C3(O)CCOCC3)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +NCCNCCCCNCC1CCN(C(=O)Cc2cccc3ccccc23)CC1 +CCCCCc1cc(O)cc(OCCCCCCCCCCC(=O)NN2CCCCC2)c1 +CSc1ccc(Cc2ccc3c(c2)C2(OC3)OC(CO)C(O)C(O)C2O)cc1 +N=C(NOC(=O)c1ccc(Cl)cc1)c1[nH]ncc1Br +CS(=O)(=O)C(CCc1ccc(-c2ccccc2)cc1)C(=O)NO +N#Cc1ccccc1N1CCN(C(=O)COc2ccc3[nH]cc(CCN)c3c2)CC1 +CN1CCc2cc(O)ccc2Cc2[nH]c3ccccc3c2CC1 +CC(C)(C)C1CC(=Cc2ccccn2)C(=O)C(=Cc2ccccn2)C1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(Nc4ccc(CN(C)C)cn4)c3c2)cc(Cl)c1O +COc1cccc(CC2(c3ccc4[nH]ccc4c3)CCNC2)c1 +CC(=CCN1CCC(Cc2ccccc2)CC1)c1ccccc1 +Fc1ccn(Cc2c(F)ccc3c2CCC3c2ncc[nH]2)n1 +CN1CCC(N(C)C(=O)c2cc3cc(Nc4nccc(-c5cn(C)cn5)n4)cc(Cl)c3[nH]2)CC1 +CCOC(=O)c1cccc(NC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Br)c(C)nc34)c2Cl)c1 +COc1ccccc1N1CCN(CCCCc2cn(-c3ccc(SC)cc3)nn2)CC1 +O=C(Nc1cnn(S(=O)(=O)c2ccc(F)c(F)c2F)c1)c1ccccn1 +CCOC(=O)C1=CC2C(CC(OC(=O)C=Cc3cn(C)cn3)C3(C)C=CC1(OC)O3)C(C)=CCC2C(C)C +CCCn1c(=O)c2[nH]c(-c3cnn(-c4ccc[n+]([O-])c4)c3)nc2n(CC)c1=O +Cc1ncc(COP(=O)(O)O)c(C=NOCC(F)CN)c1O +O=C1COc2ccc(NC(=O)C3CCN(c4cccc(F)c4Br)CC3)cc2N1 +COC(=O)c1cnc(Oc2ccc3c(c2)B(O)OC3)cn1 +CC(CC(=O)Nc1cccc(Br)c1)=NNC(=O)c1ccc(O)cc1O +Cc1nc(NC(C)c2cccc(Br)c2)cc(-c2ccc3occ(C)c3c2)n1 +COCCOc1cc2c(N)nccc2cc1CC(C(=O)O)N1CCC(NS(=O)(=O)c2cnc(N(C)C)s2)C1=O +CC(=O)N1CCCN(c2ccc(OCc3cc4cnc(C#N)nc4n3CCC3CCCCC3)cc2)CC1 +CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(N)=O)cc3)c2)CC1 +CCOC12CCC(C(=O)C1)C1C(=O)N(CCCCN3CCN(c4ccccc4OC)CC3)C(=O)C12 +COc1cccc(-c2cc(COc3cccc(Cl)c3)cc3cccnc23)c1 +CCC(=O)NS(=O)(=O)c1ccc(OC)cc1-c1ccc(Cn2cncn2)cc1 +COc1cccc(Oc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +CC(C)(C)c1ccc(Cn2c(C(=O)O)cc3sccc32)cc1 +CCN1CCC(c2ccccc2)=C(C(=O)OCCc2ccc(F)cc2)C1 +CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3NC3CCCC3)cc2)cc1 +O=C(NC1CCCC1Nc1ccc(C(F)(F)F)cn1)c1c(F)cccc1F +COc1ccc(C=C2CSCC(=Cc3ccc(OC)c(O)c3)C2=O)cc1O +Cc1ccc2ccn(C3CCN(c4ccc(-c5cnn(C)c5)nn4)CC3)c2c1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1NC1CC1 +CCC(C)(C)C(=O)Nc1cc(CN2CCOCC2)c(N)cn1 +CNc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3Cl)c(=O)n(CC3OCC(NC)CO3)c2n1 +CN(Cc1cc2c3c(c1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn3CC(=O)N2C)CC(O)c1ccccc1 +CN1CCC23Cc4nc5ccc(C(F)(F)F)cc5cc4CC2(O)C1Cc1ccc(O)cc13 +COc1ccc(-c2cc3ncccc3c(OCC3CNC(=O)N3)n2)cc1OC +C=CC(=O)Nc1ccc(OC)c(Nc2cc(-c3[nH]c(SC)nc3C)ccn2)c1 +CN1CCN(c2cccc(-c3cnn4c(N)c(-c5ccc(NC(=O)CCC6CCCC6)cc5)cnc34)c2)CC1 +CN(Cc1cccc(-c2cnc(N3Cc4cccnc4C3)nc2)c1)C(=O)CN +COc1ccc(OCCCN(C)CCOc2ccc3c(c2)OCO3)c(C2(OC)Sc3ccccc3N(C)C2=O)c1 +COc1nc2cccnc2n1C1CCC(Nc2nc3ccccc3s2)CC1 +Cc1csc(-c2nc(C3CCC(=O)CC3)[nH]c2-c2ccc3ncsc3c2)n1 +c1ccc2c(c1)CCc1ccccc1N2CSCC1CCCN2CCCCC12 +CC(CCCCNS(=O)(=O)c1ccccc1)C1CCC2C(=CC=C3CC(O)CC(O)C3)CCCC21C +CCCCc1nnc(SCC(C)C)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)cc1 +CC1(C#Cc2ccc(C(=O)Nc3ccc(F)c(C4(C(F)F)N=C(N)OC5CC54)c3)nc2)COC1 +CCCCN1CCN(c2ccc(S(=O)(=O)Oc3ccc(OC)c(OC)c3)cc2)C1=O +CCOc1ccc(N2CC(Oc3ccc(C(C)NC(=O)c4cncs4)cc3)C2)cc1 +CSc1ccc(C=CC(=O)NC(=O)c2ccccc2O)cc1 +CCCCC(OC(Cc1ccccc1)C(=O)N1CCC(O)CC1)C(=O)NC(CC1CCCCC1)C(O)C(O)CC(C)C +Cc1cc(N)nc(C)c1CNC(=O)C1=CN(Cc2nc3ccccc3nc2C)NC1 +Cc1[nH]c(C#N)c(C)c1-c1ccnc(Nc2cccc(O)c2)n1 +Cc1cc2cc(CNc3ccc4c(c3)OCO4)c(=O)n(CCO)c2cc1C +CCNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC(C)C)ncc1C(F)(F)F +CC(CCc1ccc(O)cc1)NC(=O)Cc1c(-c2ccccc2)n(Cc2ccc(OCCCN3CCCCC3)cc2)c2ccccc12 +FC(F)(F)c1ccc(C(NCC2CCCCC2)c2cnccn2)cc1 +CC(C)(C#N)COc1ccc2c(c1)C1(COC(N)=N1)c1cc(-c3cncnc3)ccc1O2 +C=CCN1CCC23c4c5ccc(O)c4OC2C(=O)CCC3(OC)C1C5 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+N#Cc1cc(Cl)c(NC(=O)N2CCN3C(=O)N(C4CC4c4ccccc4)C(=O)C3C2)c(Cl)c1 +CCCS(=O)(=O)Nc1ccc(C)c(Nc2ccc3ncn(C)c(=O)c3c2)c1 +Nc1nc(-c2ncco2)nc2sc(Cc3ccccc3)cc12 +CC(=O)OC1CC2(C)C(CC(O)C3C4(C)CCC(O)C(C)C4CCC32C)C1=C(CCC=C(C)C)C(=O)O +C=C(C(=O)O)C1CCC(C)(O)C2CC(=O)C(C)=C2C1 +NC(C(=O)N1CCC(F)C1)C1CCC(NC(=O)OCc2ccccc2)CC1 +CCNC(=O)c1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccc3)c2c1 +Oc1cccc(C23CCCCC2CN(CCc2ccccc2)CC3)c1 +CCOC(=O)C1=C(C(CC)CC)c2ccc(OCCCc3ccccc3)cc2C1=[N+](C)[O-] +CNC(=O)C1OC(n2cnc3c(NCc4ccc(Br)cc4)ncnc32)C(O)C1O +Cc1cc(C)nc(N2CC3CN(C(=O)c4cnoc4-c4ccccc4)CC3C2)n1 +CCCN(CCC)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3)cc1 +CC(C)C(O)Cc1ccc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nn12 +Cc1ccc(NC(C)c2cc(C(=O)NCCN(C)C)cn3c(=O)cc(N4CCOCC4)nc23)cc1 +OCC1OC(SC2CCCC(n3cc(-c4ccsc4)nn3)C2O)C(O)C(n2cc(-c3ccsc3)nn2)C1O +CCc1cnc(C)nc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4ccc(C(F)(F)F)c(F)c4)o3)cc2Cl)CS1(=O)=O +COc1ccc2ccc(=O)oc2c1C1=NN(C(C)=O)C(c2ccc(C(F)(F)F)cc2)C1 +CC(C)Nc1nc(-c2ccc(C(C)NS(C)(=O)=O)cc2)cc2ncn(C)c(=O)c12 +NC1=NC(CF)(c2cc(NC(=O)c3ccc(Br)cn3)ccc2F)CC(C(F)(F)F)O1 +NC1=C(C=C2COc3ccccc3C2=O)C(=O)C2C=CC=CC2O1 +O=C(c1ccccc1)c1cc(Br)ccc1OCCn1ccc(=O)[nH]c1=O +COCC1OC(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C(O)C1O +Cn1cc(-c2cnc(N)c(C(=O)NCc3c(F)ccc(F)c3Cl)c2)cn1 +COc1ccc(C(=O)Nc2c(C)nn(COc3cccc(C(F)(F)F)c3)c2C)cc1 +COc1cc(CCNCCc2ccc(F)cc2)ccc1NC(=O)Nc1cnc(C#N)cn1 +Cc1ccc(Nc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)cn1 +CCC(O)C(C)C1OC1CC(C)(O)C=CC=C(C)C1OC(=O)CC(O)CCC(C)(O)C(OC(C)=O)CCC1C +N#CC1CN(C(=O)OCC(F)(F)CO)CCC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +CCCCNc1n[nH]c2ccc(-c3cn(Cc4ccccc4)nn3)cc12 +CC1c2cc(O)ccc2CCN1Cc1ccccc1C(=O)NCCC=Cc1ccccc1 +O=C(COc1ccccc1)NC1C(=O)N2C(C(=O)O)=C(Cl)CSC12 +CC(Nc1cc(NCCc2ccccc2)ncn1)c1ccccc1 +Nc1nc(NCC2CCCN2Cc2cccnc2)nc2nc(-c3ccco3)nn12 +Cc1ccc2nsnc2c1S(=O)(=O)NCc1ccc2c(c1)OCO2 +COc1cc(OCc2csc(-c3ccc(C#N)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CC1CN(C2CC(c3ccc(F)cc3)c3ccc(Cl)cc32)CC(C)N1C +O=C(COc1ccccc1)N1CCCCC1c1nc(-c2ccc(=O)[nH]c2)no1 +O=C(O)CCc1ccc(-c2c(C3CC(c4ccc5ccccc5n4)C3)nc3c(N4CCOCC4)ccnn23)cc1 +O=C(Cc1ccccc1)NC1CCN(CCc2ccccc2)CC1 +CC1(C(=O)Nc2cc(C3CC3)n[nH]2)CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5cc6ccccc6s5)cc4s3)o2)CC1 +[C-]#[N+]C1=C(c2ccc(F)cc2F)N=C2COC(=O)C2C1c1ccc2n[nH]c(C)c2c1 +CN(C)CCn1cnnc1-c1cc(Oc2ccc(NC(=O)NN=Cc3cccc(Br)c3)cc2F)ccn1 +N#Cc1cnc2ccc(NCc3cc[nH]n3)cc2c1Nc1ccc(F)c(Cl)c1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccnc(N2CCCC2)c1 +CC1CN(Cc2ccc(-c3cccnc3C(=O)N3CCC(Nc4cccc(F)c4)CC3)cc2)CC(C)N1 +CNC(=O)Nc1nc2ccc(-c3cncc(S(=O)(=O)NC(C)(C)C)c3)cn2n1 +CS(=O)(=O)Cn1cnc2c(N3CCOCC3)nc(-c3cccc4[nH]ccc34)cc21 +Cn1c2c(c3cc(S(=O)(=O)c4cc(F)c5[nH]ccc5c4)ccc31)C1CCC(C2)N1 +N=C(N)c1ccc(OCCC2CCCCN2C(=O)C(CC2CCCCC2)NCC(=O)O)cc1 +Cc1onc(-c2cccc(F)c2)c1CNc1ccc(C(=O)NC(C)C)cn1 +CCCCCCN=c1ccn(Cc2ccc(OC)cc2)c2cc(Cl)ccc12 +Cc1cnc(NCCc2ccccc2)c(=O)n1CC(=O)NCc1ccn2ccnc2c1 +COc1cccc(C2SC(c3ccc(F)cc3)=NN2C(=O)c2c(F)cc(F)cc2F)c1OC +CC1(O)CC(c2nc(-c3ccc4ccc(-c5ccccc5)nc4c3)c3c(N)ncnn23)C1 +CC(NC(=O)C1(C)CC(C)(Cl)C1)c1ccc2ccccc2c1 +Cc1noc(C)c1Cn1cc(N2C(=O)CN(CCc3ccc(O)cc3)C2=O)cn1 +CNc1cc(-c2c(Nc3cc[nH]n3)nc3cccnn23)nc(C)n1 +COc1cncc(C2=CCC3C4CCC5=CC(=O)NCCC5(C)C4CCC23C)c1 +Cc1ccc(-c2cc(C3C(OC(c4ccc(F)cc4)c4ccc(F)cc4)CC4CCC3N4C)on2)cc1 +O=C(O)C1C2CN(C(=O)c3ccc(N4CC(F)(F)C4)c(OCC4CC4)n3)CC21 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1NC(=O)c1ccc2nc(NC(=O)Nc3cccnc3)sc2c1 +C(=Cc1cn2c(-c3ccc(N4CCNCC4)nc3)cnc(C3CCOCC3)c2n1)c1ccc2ccccc2n1 +CCc1cc2c(C3=NNC(=O)C3(C)C)ccc(CC)n2n1 +COc1cc(CN2CCC(C(=O)NC(C)(C)C)CC2)cc(NC(=O)c2ccc(F)cc2)c1 +O=C(Cc1ccc(F)cc1)Nc1nc2nn(CCCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1OC1CCN(CC(=O)N(C)C)CC1 +CC(Oc1cc(C=C2SC(=S)N(CC(=O)O)C2=O)ccc1OCCc1ccccc1)c1ccccc1 +O=C(c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1)N1CCN(c2cccc(Cl)c2)CC1 +CCCC(NC(=O)c1ccccn1)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 +COCC(=O)N1CCS(=O)(=Nc2cc(C)c3c(Nc4ccc(F)cc4OC(C)c4cc(C)no4)ncnc3c2)CC1 +CCOC(=O)C1=C(Nc2ccc3c(c2)CCCC3)SCC1=O +CCCC(C(N)=O)C(CC(C)C)C(=O)NC1CCCCN(Cc2cccc(-c3ccc(Cl)cc3Cl)c2)C1=O +CCc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(Cc3ccc(C)c(OC)c3)[nH]c(=O)c12 +Cc1ccc(-c2nc(C(=O)Nc3cccc(C(=O)O)c3)c(CCC34CC5CC(CC(C5)C3)C4)[nH]2)c(C)c1 +CCN(CC)c1ccc2cc(C(=O)NCCCCn3nc(C(=O)NC4CC5CCCC(C4)N5C)c4ccccc43)c(=O)oc2c1 +NC(=O)c1ccc(Nc2nccc(Nc3cccc(C(F)(F)F)c3)n2)cc1 +COc1cccc(C[n+]2ccc(C=C3OCc4c(ccc(OC)c4OC)C3=O)cc2)c1 +COC(=O)N1CCC(c2cccnc2OC2CC(Nc3nc4ccccc4s3)C2)CC1 +C=CCN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCC1 +COc1cccc(-c2cc(NC(C)c3cccc(Br)c3)nc(C)n2)c1Cl +O=C(NC12CC3CC(CC(C3)C1)C2)C1Cc2c(sc3ccccc23)CN1 +C#Cc1cccc(Nc2ncnc3ccc4nc(C(=N)OC)sc4c23)c1 +NCCCCn1c(SCCc2c[nH]c3ccccc23)nnc1-c1cnc2ccccc2n1 +Cc1cc(C#N)cc2nc(-c3ccc(NC(=O)COC4CCN(CC(=O)OC(C)(C)C)CC4)cc3)oc12 +CCC(C)n1ccnc1C=CC(=O)C=Cc1nccn1C(C)CC +CC(Oc1cc(-c2cn(C)nc2C(F)(F)F)cc2ncccc12)C1CNC(=O)C1 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12)N1CC(O)C1 +c1cc(NC2CCCCC2)nc(Nc2ccc3[nH]ncc3c2)n1 +COc1cc(C(C)C)c2c(c1)S(=O)(=O)N(CSc1nnnn1-c1ccccc1)C2=O +CCCc1[nH]c(C2Cc3ccccc3N2C(=O)CN)nc1C(=O)OCC +CCNC(=O)C(C)NC(=O)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +CC(C)=CCN(Cc1ccccc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +Cc1nc(-c2c(F)cc(Cl)cc2-c2cc(F)c3c(c2)CCC3NC(=O)C2(NC(=O)OC(C)(C)C)CC2)no1 +Cc1cccc(-c2nc(CNc3ccc(S(N)(=O)=O)cc3)cn2-c2ccc3c(c2)OCO3)n1 +Cc1cnc(CNCC2(F)CCN(C(=O)c3ccc(F)c(Cl)c3)CC2)cn1 +CNC(=O)c1cnc(Nc2ccc(N3CCOCC3)cc2)nc1Nc1cccc(OC(C)C)c1 +CC(C)(C)c1cc(-c2nc3nc(-c4ccccc4C(F)(F)F)cc(Cl)c3[nH]2)on1 +O=C(Nc1n[nH]c2cc(C(=O)NC(CN3CCOCC3)c3ccccc3)sc12)c1ccc(N2CCOCC2)cc1 +Cc1c(Cl)cccc1-c1noc(C2CCN2C(=O)c2cc(C(F)(F)F)ccc2-n2nccn2)n1 +CC(C)Oc1nc(Nc2ccc(OC(F)(F)F)cc2)cc(Nc2nccn2-c2cccc(C(F)(F)F)c2)n1 +O=C(NCCN1CC2CC(n3c(=O)[nH]c4ccccc43)CC2C1)c1cc2cc(F)ccc2[nH]1 +Clc1ccc(Cl)c(CN2CCN(c3nc4ccncc4nc3NC3CC3)CC2)c1 +Cc1nc(NC(C)c2ccc(OC(F)(F)F)cc2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2c(C(C)C)nccc2s1 +CCNC(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)cc2)N=C(c2cccc(C)c2)N1 +CS(=O)(=O)N1CCC(O)(c2cncnc2Nc2ccc(F)cc2)CC1 +CC(=O)N1CCN(C(=O)c2cc(Cl)cc(CSc3cnc(NC(=O)c4ccc(N(C)C)cc4)s3)c2)CC1 +CC1CNC(=O)c2cc(-c3ccnc(N)n3)[nH]c21 +Oc1ccc2c(c1)CC1(C2)C(c2ccccc2)=Cc2ccccc21 +COc1ccc(NC(=O)Nc2ccc(-c3ccc(C(=O)C4CCCC4C(=O)O)cc3)cc2F)cc1 +Cc1ccc(-c2ncccn2)c(C(=O)N2CCCOC2Cn2cc(-c3ccc(F)cc3)cn2)c1 +CC1(C)Cc2nc(N3CCOc4ccc(-c5cnn(CCN)c5)cc43)sc2C(=O)N1 +Cc1ccc(C#CC(C=CCOc2ccc(OCC(=O)O)c(C)c2)c2ccc(Br)cc2)s1 +Cc1nc(-c2ccccn2)nc(NCC(NC(=O)CCN2CCN(CCO)CC2)c2ccccc2)c1Cl +NC(Cn1c(=O)c(-c2ccccc2F)cn(Cc2c(F)cccc2C(F)(F)F)c1=O)c1ccccc1 +COC1CCC2(CC1)Cc1ccc(OCC3CCC3)cc1C21N=C(N)N(CC(F)(F)F)C1=O +N#Cc1cccc(Cn2cc(NC(=O)c3n[nH]c4cc(-c5ccncc5)ccc34)cn2)c1 +CCCCCc1[nH]c2ccc3c(c2c1C(=O)OCC)CN1CCc2cc(OC)ccc2C1O3 +CCOC(=O)CCc1cccc(-c2cc(C)cc(Nc3nccc(C4CC4)n3)c2)c1 +N#Cc1c(N)nc(N)nc1NC(c1nc2c(F)ccc(Cl)c2c(=O)n1-c1cccnc1)C1CC1 +CC1c2ncn(-c3ccccn3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1F +Cc1ccc2c(n1)C(=O)C1=C(C2=O)S(=O)(=O)C=CN1 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+Cn1ncnc1COc1nn2c(-c3cccs3)nncc2c1-c1ccccc1 +N=c1c2ccccc2c(-c2ccccc2)nn1Cc1cc(O)ns1 +Cc1cn(-c2ccc3n(c2=O)CCN(CCOc2ccccc2C2CCC2)C3=O)cn1 +CCNc1nc(-c2ccc(S(=O)(=O)CCN(C)C)cc2)cc2ncn(C)c(=O)c12 +CC(=O)N(C)C1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccccc2)c2ccc(Cl)c(Cl)c2)CC1 +CC(C)(C)c1ccc2c(c1)CCC2NC(=S)Nc1cccc2[nH]ncc12 +Cc1cc(OCc2ccccc2)cc(C)c1C=CC1CC(O)CC(=O)O1 +COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)[nH]c3ccc(Cl)cc23)CC1 +COc1ccc2c(c1)C(=O)N(c1nc(C(=O)Nc3cc(F)ccc3N3CCNCC3)cs1)C2 +O=C(O)C(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C1OCOC1C(=O)Nc1nc2ccccc2s1 +C=C(Br)C(=O)Nc1cccc(C=CC(=O)Nc2cccc(F)c2)c1 +CCN1CCN(Cc2ccc(NC(=O)c3cccc(-c4ccc5nc(Nc6ccccn6)sc5n4)c3)cc2C(F)(F)F)CC1 +N=C(N)NCC(=O)NCC1(Nc2ccc(Cl)c(Cl)c2)CCN(Cc2ccccc2)CC1 +CCCCCCN(CCCCCC)C(=O)Cc1coc(-c2ccc(C)cc2)n1 +O=C1CCCN1CCCNc1nc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2o1 +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(Cl)c3)cn2CCN2CCCC2)CC1 +Cc1cc(COc2ccc(S(=O)(=O)CC3(CC(=O)NO)CCCN(C)C3)cc2)c2ccccc2n1 +Cc1cccc(-c2nc(NCc3cccc(F)c3)sc2-c2ccc3ncnn3c2)n1 +COc1cnc(OC)n2nc(NS(=O)(=O)c3c(Cl)cccc3Cl)nc12 +C(=C(c1ccccc1)N1CCN(CCCCc2ccccc2)CC1)c1ccccc1 +N#Cc1ccc(Cn2cncc2CN2CCCN(C(=O)c3cccc4ccccc34)CC2)cc1 +COCCc1ccc(OC)cc1Nc1nc2ccccc2nc1NS(=O)(=O)c1cn(C)cn1 +Cc1cc(-c2cc(C(=O)Nc3ccc(OC(F)(F)Cl)cc3)ccc2N2CC(N)C(O)C2)[nH]n1 +OCC1CC(Nc2nc(Nc3cccnc3)ncc2-c2nc3cnccc3s2)C(O)C1O +O=C(NCCCc1ccccc1)c1ccc(NC(=O)N2Cc3cncnc3C2)cc1 +COc1cccc(-c2nc3ccccc3c(C(=O)NC(C)c3ccccc3)c2CN2CCC(N3CCCCC3)CC2)c1 +NC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(-c4c(F)cccc4Cl)c3)CC3CC32)c2cnccc12 +CC1NCc2cncn2Cc2ccc(C#N)c(c2)Oc2ccc3cccc(c3c2)N(C)C1=O +COC(=O)C(C)NP(=O)(OCC1C=CC(n2cc(C)c(=O)[nH]c2=O)O1)Oc1ccc(Cl)c(Cl)c1 +COc1cc(-c2c[nH]c(=O)c(-c3cc(OC)c(OC)c(OC)c3)n2)ccc1O +Cn1c(N2CCN(c3ccccn3)CC2)nc2c1c(=O)n(Cc1ccc(Cl)cc1)c(=O)n2C +N#CCC(=O)N1CCCCC12CCN(c1ncnc3nc[nH]c13)C2 +CNC(=O)COc1ccc(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)c(C(=O)NC)c1 +Nc1ncnc2c1C(=O)N(c1ccc(C3CCC(Cc4nn[nH]n4)CC3)cc1)CCO2 +CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc32)cc(CCC)c1OC(C(=O)O)c1ccc(CC)cc1 +CCCN1CCc2cc(OCCO)cc3c2C1Cc1cccc(O)c1-3 +Cc1cc(=O)oc2cc(OCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)ccc12 +COCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C#N +O=C(NS(=O)(=O)c1ccc(Cl)cc1)c1cc2ccccc2n1Cc1cccc(C(F)(F)F)c1 +Cc1cn(CCCn2c(=S)[nH]c3sc4c(c3c2=O)CCCCCC4)cn1 +CCC1(CCC(C)C)CN(C2CCCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O +O=C(C#Cc1ccccc1)N1CCN(c2ncccc2[N+](=O)[O-])CC1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCC(C(F)F)C3)n2)cc1OC(F)F +COc1cc(C(=O)NCc2c(F)cc(F)cc2F)ccc1-c1cn[nH]c1 +CC(=O)COc1ccc(C23c4ccccc4C(=O)N2CCN3C(=O)c2ccc(F)cc2)cc1 +CC(C)C(NC(=O)c1cc(C(=O)NCc2cnccn2)c2n1CCOC2)c1ccc(F)cc1 +C#CCN(Cc1ccc2nc(C)[nH]c(=O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +COc1ccc(Cc2nc3c(ncn3C(CCCc3ccccc3)C(C)=O)c(=O)[nH]2)cc1OC +CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1CCC(C(C)(C)C)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +COc1cc2c(Nc3ncc(CC(=O)Nc4ccccc4C(N)=O)s3)ncnc2cc1OCCCN1CCCC1CO +Cc1noc(C)c1-c1ccc2[nH]nc(-c3cc(N4CCOCC4)ncn3)c2c1 +CCCn1c(=O)c2[nH]c(-c3cc(OCC#Cc4cccc(F)c4)no3)nc2n(CCC)c1=O +Cc1cc(Nc2ncc(-c3nc4cnccc4s3)c(NC3CC(CO)C(O)C3O)n2)ccn1 +Oc1cc(O)cc(CNC2COC(C(c3ccccc3)c3ccccc3)CC2O)c1 +O=C(NCC(F)(F)F)Nc1cncc(-c2cnc3cc(Cl)ccn23)c1 +C=CCn1c(=O)c2c(-c3cc(C#N)cn3C)n(Cc3ccnc4ccc(Cl)cc34)nc2n(CC2CC2)c1=O +CCOC(=O)c1nnc(Nc2cccnc2Oc2ccccc2C(C)(C)C)s1 +CCOC(=O)c1c[nH]c2ccc(OCc3ccc(OC(F)(F)F)cc3)cc2c1=O +Cc1nc(C#Cc2ccc(-c3cccc(Cl)c3C)nc2)cs1 +CN(C)C=Nc1nc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(C#N)cc2)n1 +Cc1ccccc1C1=CCC(C)(C)c2ccc(C#Cc3ccc(C(=O)O)cc3)cc21 +Cc1c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)ccn2cc(C#N)cc12 +Nc1ccccc1-c1ccc2c(c1)sc1c(N)ncnc12 +CCOP(=O)(c1ccc(N)cc1)N1Cc2ccccc2CC1C(=O)NO +O=C(c1cccc2c(CN3CCN(C4CCC4)CC3)c[nH]c12)N1CCCCC1 +N#Cc1c2c(c(O)c3ncc(Cc4cccc(Cl)c4F)cc13)C(=O)N1CCCC21 +COc1cccc(-n2cc(C(=O)N3CCN(c4ccc5ncccc5c4)CC3)nc2-c2ccc(C)cc2)c1 +CC1(C)OC(=O)C(Nc2ccccc2)=C1c1ccc(S(C)(=O)=O)cc1 +COc1cc2c(C(O)CCCN(C)C)cc3c4cc5c(cc4ncc3c2cc1OC)OCO5 +C=CCN1C2CCC1C1CCC2N1C(c1ccc(C(=O)N2CCCC2)cc1)c1cccc(O)c1 +CN(C(=O)Cc1cccc2sccc12)C1CCCCC1N1CCC(CO)C1 +Cc1ccc(C(CO)Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1 +COc1cc(C=C2CCCN3C2=NOCC3C(O)c2ccc(Cl)cc2)ccc1-n1cnc(C)c1 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)CNC(C)(C)CCCC(C)C)cc13)N(C)S(=O)(=O)C2 +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1CCN1CCOCC1 +CN(C)CCNC(C(=O)NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccc(F)cc1 +COCC(=O)Nc1ccc2[nH]nc(-c3cc4ccc(C)cc4[nH]3)c2c1 +COc1ccc2c(c1N)CCC=C2c1cc(OC)c(OC)c(OC)c1 +CN(C)C1CCN(CCc2c(COc3ccc(Br)cc3C(N)=O)sc3ccccc23)CC1 +C[Si](C)(CN1CC(O)C(O)C(O)C1CO)c1ccccc1 +O=C1NC(=O)c2c1c1c3ccccc3n3c1c1c2c2ccccc2n1C1CCC3N1 +CC1CN(c2nc(N3CCOCC3)c3ccc(Nc4ccncc4)nc3n2)CC(C)O1 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3C(O)CC2(C)C1(O)C(=O)CSc1nc2ccccc2s1 +Cc1cccc(Cl)c1NC(=O)c1cnc(NC(=O)c2ccsc2)s1 +CC(=O)Nc1cc(N2CCCC2CO)nc(-n2nc(C)cc2C)n1 +c1ccc(CNc2nccc(Nc3cc(C4CC4)[nH]n3)n2)cc1 +c1cc[n+](CCCCCCC[n+]2cccc3ccccc32)cc1 +CNC(=O)c1cnccc1Nc1nc(-c2cc(Cl)ccc2F)nc2ncccc12 +CC(=O)N1CCC(NC(=O)NC23CC4(F)CC(F)(CC(F)(C4)C2)C3)CC1 +CC(C)(C)OC(=O)N1CCC(COC2CCC(c3ccc(S(C)(=O)=O)cc3F)CC2)CC1 +Cn1nc2c(c1-c1ccccc1)-c1nc(Nc3ccn(CCN4CCN(CCO)CC4)n3)ncc1CC2 +CC(=O)Nc1nc(Cc2nnc(SCC(=O)NN=Cc3ccccc3)n2NC(=O)c2ccccc2)cs1 +CC(=O)N1CCC(n2cc(-c3coc4c(OC(C)c5c(Cl)ccc(F)c5Cl)c(N)ncc34)cn2)CC1 +O=C(CCCCCNc1c2c(nc3cc(Cl)cc(Cl)c13)CCCC2)NCCc1c[nH]c2ccccc12 +CCN(CC)C(=O)NC(C(=O)N1CCCC1C(=O)Nc1nc(-c2ccccc2)cs1)c1ccccc1 +CC1=C(N2CCC3(CCN(CC(O)c4ccc5c(c4F)COC5=O)CC3)C2=O)COC1=O +N#CC(Cc1ccc(-c2ccc(C(N)=O)cc2)cc1)NC(=O)C1NC2CCC1CC2 +CCC(CC)C(=O)Nc1cc(-c2ccccc2)nc(-c2ccccc2)n1 +ON=C1c2ccccc2-c2ccc(OCCN3CCCCC3)cc21 +Cc1noc(C)c1S(=O)(=O)N1CCCN(C(=O)c2cccc(Cc3nnc(O)c4ccccc34)c2)CC1 +Cc1ccc(OC(=O)N(CC(=O)O)Cc2cccc(OCc3nc(-c4ccccc4Cl)oc3C)c2)cc1 +COCCCOc1cc(C(=O)N(CC2CNCC2OCc2cccc3ccccc23)C(C)C)ccc1OC +N#Cc1ncc2cc(Cc3ccc(Cl)cc3)n(CCC3CCCCCCC3)c2n1 +COc1cccc2c1c(NS(=O)(=O)c1cccc(Cl)c1Cl)nn2C +O=C(CCCN1CCC(C(=O)c2ccc(F)cc2)CC1)c1ccc(F)cc1 +COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1OCCCN(C)CCO +CN1CC(NC(=O)Nc2cccc(-c3nnnn3C)c2)C(CN2CCCC(Cc3ccc(F)cc3)C2)OC1=O +O=C(c1nn(-c2ccc(CN3CCCCC3)nc2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CCc1ncnc(-c2cc(F)c(C(=O)N3CCN(C)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +[N-]=[N+]=Nc1ccc(CN2CCN(CCCN(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1I +COc1ccc(CCNCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)cc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCNC(=O)CCSSc4ccccn4)cc3)[nH]c2n(CCC)c1=O +O=C(NCC1(c2ccccc2)CCCCC1)C1CCOc2ncccc21 +Cc1cccc(NC(=S)n2cc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)n2)c1 +C=Cc1ccc2c(-c3ccnc(NC4CC4)n3)cnn2n1 +CC(NCCc1ccccc1)c1nc2c(C(N)=O)cccc2[nH]1 +N#CC1CCCN1C(=O)CNCCNc1ccc(C(F)(F)F)cn1 +Cc1c(Cl)cccc1S(=O)(=O)N1CCCC(C(=O)NC2CCCCC2)C1 +c1ccc2c(c1)CCC2CCCN1CCN(c2cccc3c2OCCO3)CC1 +O=C(Nc1ccccc1)C1=C(O)CCn2c1nc1ncccc12 +NS(=O)(=O)OCC1CC(Nc2ncnc3nc(-c4cccc5cccnc45)[nH]c23)CC1O +NS(=O)(=O)c1ccc(NC(S)=NC(Cc2c[nH]cn2)C(=O)NCC(=O)O)cc1 +Cc1cc(O)cc(C)c1CC(C(=O)N1Cc2ccccc2CC1C(=O)O)N(C)C +Cc1ccc2nc(NC(=O)CNC(=O)c3nn(-c4ccccc4)c(=O)c4ccccc34)sc2c1 +O=C(NCc1ccccc1)OC1COC2C(OC(=O)c3ccccc3O)COC12 +CC1(C)CC(=O)c2c(ccc3c2C(c2ccc(Cl)cc2)Oc2ccccc2-3)N1 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+COCCN1CC(C(=O)N2CC(C)C(O)(c3ccccc3)C(C)C2)C(c2ccc(F)cc2F)C1 +O=S(=O)(c1ccc(Cl)cc1)N1CC=C(c2ccc3[nH]cc(CCN4CCCC4)c3c2)CC1 +Cc1ncnc(-c2ccc(C(C)(C)C#N)cc2)c1C#Cc1ccc(N)nc1 +CCS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CCCN1CCN(C(=O)CO)CC1)CCCC3)C(=O)N2 +Cc1csc(Cc2c(C3CCC(c4ccccc4)CC3)[nH]c(=O)[nH]c2=O)n1 +CNCC(=O)NC(c1cccc(F)c1N1CCN(C(=O)C(C)Cc2ccc(Cl)cc2Cl)CC1)C(C)C +O=C(NCC1(c2ccc(Cl)cc2)CCOCC1)c1ccccc1Cl +OCCNc1cc(C(F)(F)F)nc2c(C(F)(F)F)cccc12 +CNc1nc(Nc2cnn3c2C(C)OCC3)ncc1C(F)(F)F +CN1CCOCC1c1nc(O)c(O)c(C(=O)NCc2ccc(F)cc2)n1 +CCCCCCC(C)(C)c1ccc(-c2cc(C)cc(C)c2)c(CN2CCOCC2)c1 +CCNN(CC(=O)N1CSCC1C#N)C1CCN(CC(=O)Nc2ccc(Cl)cn2)CC1 +CCc1ccc2c(c1)[nH]c(=O)c1nc(-c3ccccc3Cl)[nH]c12 +Fc1ccc(C23CCN(CC2)Cc2cc(-c4ccc(C(F)(F)F)nn4)ccc23)cc1Cl +Cc1cnc(Nc2cnn(C)c2)nc1NC1CC2CN(c3ccc(C#N)cn3)CC2C1 +O=C(O)c1ccc2nc(Nc3cccc(Cl)c3)c3cccn3c2c1 +CN1C2CCC1C(C(=O)OCCc1ccc(N)cc1)C(OC(=O)c1ccccc1)C2 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCCc3cccs3)[nH]c3ccc(Cl)cc23)c1 +COCC(=O)n1nc(-c2ccc(C)cc2)nc1NCc1ccc(F)cc1 +CC(=O)CC1(O)c2ccc(Br)cc2-[n+]2ccc3c([nH]c4ccccc43)c21 +O=C(NC1CCCN(CC2CC2)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +COCCNc1cc(Nc2ncc(F)c(-c3cnc(N4CCCOCC4)c(C#N)c3)n2)ccn1 +CCNc1nc(C#Cc2ccc(Cl)s2)nc2c1ncn2C1C(O)C(O)C2(C(=O)NC)CC12 +Fc1ccc(C(OCCN2CCN(Cc3ccc4ncccc4c3)CC2)c2ccc(F)cc2)cc1 +Nc1nc(-c2ccc3c(N)n[nH]c3c2)cc(N2CCCC(NC(=O)c3ccccc3)C2)n1 +CN(C)CCCOc1ccc(-c2nc3ccccc3n2CC=CCn2c(-c3ccc(OCCCN(C)C)cc3)nc3ccccc32)cc1 +C=CCS(=O)(=O)c1ccc(Nc2ncc(C(F)(F)F)c(OC(C)C(C)(C)O)n2)cc1 +CCCCCCCC[n+]1ccc(C(=O)NCCCCCCNC(=O)c2cc[n+](CCCCCCCC)cc2)cc1 +CC1(C)CCN(c2cnc(C#Cc3ccccc3)cn2)C(=O)N1 +CCOC(=O)N1CCC(NCCNC(=O)c2ccccc2C)CC1 +CCN(CC)CCCNc1cc(Nc2cc(C(C)C)[nH]n2)nc(NCc2cc(C(C)C)no2)n1 +CCc1cc(-c2ccc(-n3c(C)cc(C=C4SC(=O)NC4=O)c3C)cc2)ccc1C=C1SC(=O)NC1=O +CCCSc1sc(-c2cc[nH]n2)c2c1C(=O)NCC2CC +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(C(=O)CC#N)CC2)CC1c1ccc(Cl)cc1 +CC(C(=O)NC(CCCCCC(=O)NO)C(=O)Nc1cccc2cccnc12)c1ccc(N2Cc3ccccc3C2=O)cc1 +N#Cc1ccc2[nH]cc(C3=CCC(N4CCCCC4)CC3)c2c1 +COCCOCCOCC(=O)N1CCC(c2nc(-c3ccc([S+](C)[O-])cc3)c(Sc3ccc(Cl)cn3)o2)CC1 +CC(C(=O)OC1C[N+]2(CCOc3ccncc3)CCC1CC2)(c1ccccc1)N1CCCCC1 +O=C(NCC1CCCNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 +CC1(O)CCC2C(CCC3C2CCC2(C)C(C(=O)Cn4ncnn4)CCC32)C1 +CCc1c(N)ncnc1N1CCC(c2nc(-c3cccc(C(F)(F)F)n3)cn2CCN2CCC2)CC1 +CC(Cc1ccc(-c2ccccc2)cc1)SC(=O)C(C)NC(=O)CCC(=O)c1ccccc1 +COc1ccc(-c2c(C(=O)O)c(C(N)=O)cc3ccc4c(c23)OCO4)cc1OC +Cc1csc2c(NC(C)CN3CCN(S(=O)(=O)c4cccc(Cl)c4)CC3)ncnc12 +CC1CCN(c2nc(C(F)(F)F)ccc2CNC(=O)Cc2cc(Br)cc(Br)c2)CC1 +CCS(=O)(=O)N1CCN(Cc2ccccc2C2(O)CCN(C(c3ccccc3Cl)c3ccccc3Cl)CC2)CC1 +Cc1oc2ccc(NC(=NC#N)NC3CCCCN(CC(=O)N4CCCC4)C3=O)cc2c1C +Clc1cc(NCCCN2CCOCC2)c2cc3c(nc2c1)c1ccccc1n3CCN1CCCC1 +Cc1nc(N)sc1CCCNC(=N)NC(=O)CC(C)c1ccccc1 +CCCCCCCCCCOC(=O)C1=C(c2ccccc2)CCN(CC)C1 +O=C(Cc1cc[n+]([O-])cc1)N1CCN(C2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c32)CC1 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cc(N)cc(C#N)c1 +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)NCc1cccc(F)c1 +CCOC(=O)c1cnc(SC)nc1NN1C(=O)C=C(C)C1=O +Cc1ncoc1-c1nnc(SCCCN2CC3CCN(c4ccccc4)C3C2)n1C +O=c1cc(N2CC3CC2CO3)nc2n1CCC(C(F)(F)F)N2CC1(O)CC1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CCC(C3)N4CC(=O)N(C)CCO)cc12 +c1ccc(-c2cc(CCCCN3CCN(c4ccccc4)CC3)on2)cc1 +COc1ccc2c(c(CCNC(C)=O)c(I)n2C)c1[N+](=O)[O-] +CCC(CC)C(=O)Nc1ccc(N2CCN(C(c3ccccc3)c3nc(C)no3)CC2)c(F)c1 +CCCCN1C(=O)C(=CNC2CCCCC2)C(=O)c2c(C)cccc21 +CONC(=S)NN=C1C(=O)N(CN2CCN(c3ccc(Cl)cc3)CC2)c2ccc(Cl)cc21 +N=C(N)NCCCC(NC(=O)C1c2ccccc2-c2ccccc21)C(=O)NCc1ccc(C(F)(F)F)cc1 +Cc1ccc2[nH]c(-c3ccc[nH]3)c(C3CC(=O)NC3=O)c2c1 +Cc1ccccc1N1CCN(CC(O)CN2CCC(c3ccccc3)(c3ccccc3)C2=O)CC1 +Cc1cccn2cc(-c3ccc(OCCCCN4CCN(c5cccc(Cl)c5Cl)CC4)cc3)nc12 +Cc1cc(C(C)(C)C)nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)n1 +Nc1nc(N)c2nc(CCc3cccc4ccccc34)cnc2n1 +COC(=O)c1ccc(Oc2cccc(C(=N)N)c2)c(NC(=O)c2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN2CCN=C2SC)c1Cl +O=C(Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1)C1CCC2(CC1)OOC1(OO2)C2CC3CC(C2)CC1C3 +OC1COC(C(c2ccccc2)c2ccccc2)CC1NCc1ccccc1 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+O=c1[nH]c(CCCN2CC=C(c3ccccc3)CC2)nc2cccc(Cl)c12 +CC(C)CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O +COc1cc2c(cc1OC)CN(CCCCn1cc(CCF)c3ccccc31)CC2 +c1ccc(C2=NCC(N3CCN(c4ccccc4)CC3)CCN2)cc1 +Cn1nccc1-c1cc(C(F)(F)F)cc2[nH]ncc12 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2(O)Cc1ccc2ccccc2c1 +Cc1ccccc1-n1c(Cn2nc(-c3ccc4nc(N)ccc4c3)c3c(N)ncnc32)cc2cccc(C)c2c1=O +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2cc(F)ccc2n1CC(=O)O +CCCc1nc2c(C)cc(C(=O)NCCCc3ccccc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCNc1n[nH]c2cc(NC(=O)NC3CNc4ccccc4C3)ncc12 +Cc1ccc(CN2CCC(Oc3cccc(C(=O)N(C)CCN(C)C)c3)CC2)cc1C +COc1cc(OC)cc(C(=O)NC2CCN(CC=Cc3ccccc3)C2)c1 +CC1CCCN1CCOc1ccc(C2Oc3ccc(O)cc3SC2c2ccc(O)cc2)cc1 +CCCCc1nnc(SCc2ccc(C(=O)O)cc2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(Cc4ncco4)c4ccccc43)CC2)C(C)C)c1 +O=C(O)C(CC#Cc1ccc(F)cc1F)NCP(=O)(O)O +CN(Cc1ccccc1)S(=O)(=O)Nc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 +O=S(=O)(c1ccccc1)c1c[nH]c2cccc(CCNC3CCCC3)c12 +CCOC(c1cccnc1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +COCC(F)(F)CN1CCN(C(=O)c2cc3c(cc2C)[nH]c(=O)c2cnn(C4CCOC4)c23)CC1 +COc1cc(-c2ccc(C(F)(F)F)cc2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CCC(C)(C)n1nnnc1C(c1ccc(O)cc1)N1CCc2ccccc2C1 +CCN(CC)c1ccc(CN(CCc2ccccc2)S(=O)(=O)c2ccc(C)cc2)cc1 +CCCCCCCCCCC1(NC(=O)Nc2c(CC)cccc2CC)CCCC1 +CC(=O)N1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc21 +CCOC(=O)c1[nH]c(C#N)c(-c2ccc(OC)c(OC)c2OC)c1Br +NCc1ccc(CNc2nc(NCc3ccccc3Cl)ncc2[N+](=O)[O-])cc1 +CC(C)C(=O)N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +Cc1cccc2sc(-c3ccc(NC(=O)C4CCN(S(=O)(=O)c5cccs5)CC4)cc3)nc12 +NCCCCNC(=O)c1cccc(Nc2nccc(-c3cccnc3)n2)c1 +COc1cc2ncnc(N3CCOC(c4ccccc4Cl)C3)c2cc1OC +CN1C(=N)NC(C)(c2cc(NC(=S)c3ccc(C(F)(F)F)cn3)cc(F)c2F)CS1(=O)=O +COc1cccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC4CCCN4CC2Cc2ccccc2)C3(C)C)c1 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(S(=O)(=O)c3ccccc3)CC2)cc1 +CCCn1c(=O)c2c(nc(C=Cc3cccc([N+](=O)[O-])c3)n2C)n(CCC)c1=O +COc1cnccc1-c1cccnc1Oc1ccc(C(=O)c2nc3ccccc3[nH]2)cc1 +COc1cc2cc(C(=O)N3CC(CCl)c4ccc(N)cc43)[nH]c2cc1OCCN(C)C +CCCc1n[nH]c2c1C(c1ccc(OC)cc1)c1c(nc3c(c1N)CCCC3)O2 +O=C(O)c1ccc(C(=O)Nc2ccc3c(OCc4cccc(Cl)c4)cccc3c2)cc1 +COC(=O)c1cccc(-c2cnc(C(=O)CCc3ccc(-c4ccc(CN5CCSCC5)cc4)cc3)o2)n1 +CCOc1cccc(CN2CCCC(N3CCc4cc(OC)c(OC)cc4C3)C2)c1O +O=C(NCC(O)C(=O)O)c1ccc(CN(C(=O)Nc2ccc(SC(F)(F)F)cc2)c2ccc(C3CCCCC3)cc2)cc1 +O=C(NC1CNCC(F)(F)C1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccccc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 +CCN(Cc1cccnc1)C(=O)c1ccc(Cl)c(C2(C)C(=O)N(Cc3ccc(OC)cc3OC)c3ccc(Cl)cc32)c1 +O=C(CCCCCCc1nc(-c2cccc(Br)c2)cs1)NO +C=CCN1CC=C(C2=Cc3ccccc3Oc3ccccc32)CC1 +CC(NC(=O)C(F)F)c1ccc(OC2CCN(c3ccc(OCC4CC4(F)F)cn3)C2)cc1 +CC(C)c1nc2ccccc2c(=O)n1-c1ccc(OCCCN2CCCC2)cc1 +O=C(CSc1oc(-c2ccc(Cl)cc2)nc1[P+](c1ccccc1)(c1ccccc1)c1ccccc1)c1ccccc1 +CC(C)c1nn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-c3cccnc3)c12 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2c(c1)ncn2CC=C(C)C +Cc1cccc(NC(=O)CN2CCN(c3ccccc3C#N)CC2)c1 +CC(C)(C)C(=O)Nc1nc(-c2ccccc2)cc(-c2ccccc2)n1 +Cn1c(=O)c2ccccc2n(Cc2nc3ccccc3n2CCCCF)c1=O +COc1ccc(S(=O)(=O)N(Cc2ccc(N3CCN(C)CC3)cc2)c2c(C)cccc2C(=O)NO)cc1 +COc1cc(N)ccc1C(=O)NC(=O)NC1CC2CCC(C1)N2C +Nn1c(CCCCN2CCN(c3ccc4ccccc4n3)CC2)nc2ccccc2c1=O +OB(O)c1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1 +CC(C)(NC(=O)c1ccc(N2CC(F)(F)C2)c(-c2cccc(Cl)c2)n1)c1nccs1 +O=C1Nc2ccccc2C1=Cc1cc[n+](Cc2ccccc2Br)cc1 +CCOc1c(CN2CC3(CC(N4CCC(C)(C(=O)O)CC4)=NO3)C2)cc(C2CC2)c(-c2ccc(F)cc2)c1C +CCCn1c2cc(OCc3ccccc3)ccc2c2cc[n+](Cc3ccccc3F)c(C)c21 +CCOC(=O)c1csc(C(Cc2ccc([N+](=O)[O-])cc2)NC(=O)c2cccc3ccccc23)n1 +COC(c1ccc(Cl)cc1)(c1ccc2c(c1)c(-c1ccccc1F)cc(=O)n2C)c1cncn1C +Cc1ccc(C2CN(C(=O)C3CCNCC3)CC2c2ccc(C#N)cc2)cc1 +O=C(NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1)C1CC1(F)F +CCCCCCCCCCCCCCCC(=O)OC1=CC2C(=O)C3(C=C(C)C(O)C3(O)C1O)C(C)CC1C2C1(C)CO +CCCc1nc(SC(F)F)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)CC2CCCCC2)cc1 +CNC(=O)c1cc(-c2ccc(Cl)cc2Cl)c(CN)c(C)n1 +NCCC(=O)NCCOc1cc(-c2ccccc2Cl)c2ccc(=O)n(-c3c(Cl)cccc3Cl)c2c1 +COc1ccc(CC(=O)N2CCN(c3nc(Nc4cc(C)[nH]n4)c4cccn4n3)CC2)cc1 +FC(F)(F)c1cc(Cl)c(-n2cc3c(n2)CCC3(F)F)c(Cl)c1 +COc1cc2ncn(-c3cc(OCc4ccccc4C(F)(F)F)c(C(N)=S)s3)c2cc1OC +Nc1ccc(CC(C(=O)O)c2cn(CC3CCCN(C(=O)C(c4ccccc4)c4ccccc4)C3)cn2)cn1 +COC(=O)C(c1ccccc1)C1CCCCN1Cc1ccc(Cl)s1 +CCC(=O)N1c2ccccc2-c2nnc(SC)nc2OC1c1cc(OC)c(OC)c(OC)c1 +Nc1ncc(C(=O)NC2CC2)c2ccc(-c3cccc(F)c3)nc12 +Cc1ccn(CC(=O)C2CCC3C4CCC5CC(C)(O)CCC5C4CCC23C)n1 +C=CCNC(=O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O +O=C1OC(c2ccc([N+](=O)[O-])cc2)=NC1=Cc1cccnc1 +COc1cccc(C2(c3cc(OCc4ccc5ccccc5n4)ccc3-c3n[nH]c(=O)o3)CC3CCC2C3)c1 +COc1ccc(CN2C(=O)c3cccc(N4CCN(Cc5c(F)cccc5F)CC4)c3C2=O)cc1OC +COc1cccc2c1-c1ccc(NS(C)(=O)=O)cc1C(c1cccc(Oc3ccccc3)c1)O2 +CC(=Cc1sc2ccc3occc3c2[n+]1CCO)C=C1Sc2ccc3ccoc3c2N1CCO +CN1CCN(c2ccc(Nc3ncc4cc([N+](=O)[O-])c(=O)n(C5CCCC5)c4n3)cc2)CC1 +CSc1cccc(NC(=O)Nc2ccc(OS(N)(=O)=O)cc2)c1 +O=S(=O)(Nc1ncns1)c1cc(F)c(OCC2CN(CC(F)F)CCC2c2ccc(Cl)cc2)cc1F +Cc1ccc(CN(C)Cc2ccccc2)cc1NC(=O)c1ccc(Nc2ncc(C)c(C)n2)cc1 +CC1(COc2ccc(-c3ccc(F)cc3)nc2)Cn2cc([N+](=O)[O-])nc2O1 +Cn1nnc2ccc(C(c3ccc(OS(N)(=O)=O)cc3)n3cncn3)cc21 +CC(C(O)c1ccc2c(c1)CC(=O)N2)N1CCC(c2ccccc2)CC1 +CC(=O)N1CCC(N(C)C(=O)NC2CCC(c3cc(F)cc(F)c3)CC2)CC1 +Cc1ccc(NC(=O)CC2CC2)cc1-c1ccc(C(=O)NCC2CC2)cc1 +CCNC(=O)c1cc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)c(C)cc1C1CCC1 +Cc1cc(C)cc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(S(C)(=O)=O)cc2)c1 +CCc1cccc(CC)c1-c1cc(OC)c2c(n1)CCCC2N(C)c1cc(OC)ccc1Cl +CN(C)S(=O)(=O)c1ccc(Nc2cc(NC3CCC(N)CC3)nc3c(Br)cnn23)cc1Cl +CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1OC +CC1CCN(Cc2ccc3nc(NC(=O)NN=Cc4ccc(OCc5ccc(Cl)cc5)cc4O)sc3c2)CC1 +CNCCC(c1cccc(F)c1)N1C(=O)C2(CCCCC2)c2ccccc21 +O=C1Nc2ccc(C(=O)NC(CO)c3ccc(F)cc3)cc2C1=Cc1ccc[nH]1 +CC1(C)CCC(C)(C)c2cc3c(cc21)CCCc1c(-c2ccc(C(=O)O)cc2)cn(Cc2cccnc2)c1-3 +CC(C)N(C(=O)C1CCC2C3CCc4c(ccc(C(=O)O)c4Cl)C3CCC12C)C(C)C +O=C(O)CCN(C1(C(=O)NO)CCC1)S(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1 +CC1CCCN(c2ncnc3[nH]cc(-c4cnc5cc[nH]c5c4)c23)C1 +CN(C)CCNc1n[n+]([O-])c2c3c(ccc2[n+]1[O-])OCCC3 +C=CCNc1nc(NCC=C)nc(N2CCC(NCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)n1 +[H]C([H])([H])N(c1ncc(-c2nc3ccc(O)cc3o2)cn1)C([H])([H])[H] +O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(-c3ncc(C(F)(F)F)[nH]3)c2)cc1Cl +NC(=O)c1ccc2[nH]c(-c3ccc(C(=O)C4CCCCC4)cc3)nc2c1 +c1ccc(CNc2ccc3c(c2)C24CCCCC2C(C3)N(CC2CC2)CC4)cc1 +COc1cccc(-c2cnc(N)nc2-c2c[nH]c3ccccc23)c1 +CN(C)C1CCN(c2ccc(NC(=O)CCCC(=O)c3ccccc3)cc2)C1 +O=c1cc2c(nn1Cc1ccc(C(F)(F)F)cc1)CCNCC2 +COc1ccc(CC(=O)N2CCN(c3ccc(C4=NNC(=O)CC4C)cc3)CC2)cc1 +COc1cc(-n2c(-c3cccc4cc[nH]c34)cccc2=O)cc(OC)c1OC +CC#Cc1cncc(-c2ccc3c(c2)C2(CO3)N=C(N)CC2C(F)(F)F)c1 +C#CCCCn1c(Sc2ccc(Br)cc2Cl)nc2c(N)ncnc21 +CCC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(C#CCCCC(=O)N3CCOCC3)c2c(=O)n1-c1ccccc1 +Cc1nnc(-c2ccc(-c3ccc(-c4nc5nc(OC6COC7C(O)COC67)[nH]c5cc4Cl)cc3)cc2)o1 +COc1c(NC(=O)C(=O)c2ccc(OCCCCN3CCOCC3)c3ccccc23)cc(C(C)(C)C)cc1NS(C)(=O)=O +CSc1ccc2ccn(C3OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C3O)c(=O)c2c1 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+Cc1ccc(-c2c(-c3ccc(S(C)(=O)=O)cc3)ccc(F)c2F)cc1 +OC(c1cccnc1)(c1cccc(F)c1)c1ccccc1Cl +O=C(C1CCCN(c2ccc3nc(C4(n5cc(C(F)(F)F)cn5)CC4)[nH]c3n2)C1)N1CCCC1 +CN(CC=Cc1ccc(Cl)cc1)Cc1ccc2c(c1)CCCC2 +CC(NC(=O)Nc1cc2[nH]nc(-c3cnn(C)c3)c2cn1)c1ccccc1 +Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(-c3ccnc(N)n3)cc21 +Cc1cc(OCC(=O)O)cc(C)c1Cc1ccc(O)c(C(C)C)c1 +O=C(O)CN1C(=O)C(NC(=O)C(S)Cc2ccccc2)CSC1c1ccccc1 +Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccccn3)nn2)CC1 +CC(C)(C)c1ccc(NC(=O)c2ccccc2Cn2ccc3cnccc32)cc1 +Fc1cccc(C2CC2CNCCc2ccnc(-n3ccnc3)n2)c1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccnc(N3CCNCC3)c2)cc1Cl +CNC(=O)CCn1cc(-c2cnc(N)c3c(-c4ccc(Oc5ccccc5)cc4)csc23)cn1 +CC(c1ccccc1)c1ccc2c(n1)Nc1ccc(-n3cnc(Cl)c3)cc1NC2=O +CCn1ncc(CN2CCCC(C(=O)c3cccc(OC(C)C)c3)C2)c1C +c1ccc2c(c1)OCC(c1nc3ccc(-c4ccncc4)cc3[nH]1)O2 +Cc1n[nH]c2c(C)cc(C(=O)N3C4CCC3CC3(Cc5cn(C(C)(C)C)nc5C(=O)N3)C4)cc12 +Cn1c2ccnc(Cl)c2c2nc(CN3CCOCC3)nc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c21 +O=C1CC2(Cc3ccc(NC(=O)Cn4c(=O)n(-c5ccccn5)c5ccccc54)cc3C2)C(=O)N1 +NCCCOc1ccc(Cl)cc1C(=O)Nc1ccc2c(c1)S(=O)(=O)C=C2 +O=C1CC2(CCN(c3c(Cl)cncc3-c3ccc(N4CCOCC4)cc3)CC2)C(=O)N1 +O=C(NC1(c2ccccc2)CCCCC1)C1CCCC1c1cc(-c2ccccc2)on1 +Cc1cccc(Cl)c1NC(=O)c1cnc(Nc2cc(N3CCOCC3)ncn2)s1 +CC(C)(Cc1ccc2ccccc2c1)NCCCOc1cccc(Cl)c1C#N +CN1CCCC1C1C[S+]([O-])C(c2ccccc2)(C2CCCCC2)O1 +COc1cccc(C23CC2CN(CCCSc2nnc(-c4ocnc4C)n2C)C3)c1 +COc1ccc(C2=NNC(=O)C3CCCCC23)cc1OC1CCCC1 +CCOC(=O)C(Cc1ccccc1)Nc1nc2ccc(C(C)C)cc2o1 +Cc1nn(-c2ccnc(Nc3ccc4c(cnn4C)c3)n2)cc1CN1CC(O)C1 +CN1CCC(CNc2ccc(C(=O)Nc3n[nH]c4cc(OCCOCc5ccccc5)ccc34)cc2)CC1 +Cc1[nH]nc2c1C(c1cc(-c3ccc(Cl)s3)cc(C(F)(F)F)c1)(C(C)C)C(C#N)=C(N)O2 +Cc1cc(OCCCN2CCCC2=O)cc(C)c1-c1cccc(COc2ccc(CCC(=O)O)c(F)c2)c1 +CS(=O)(=O)c1ccc(C2=C(c3ccc(F)cc3)C(=O)N(c3ccc(C(F)(F)F)cc3)C2)cc1 +CSc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 +CCCNC(CCC(C)C)Cc1ccc(OC)c(OCCc2ccccc2)c1 +C=C(c1cc(C)cc(C)c1OCC(O)CNC(C)C)n1ccnc1 +COCCN(C)c1ccc(NC(=O)c2nc(-c3ccccc3)oc2C(F)(F)F)cc1 +COC(=O)C1C2CCC3CCC1N(CC2=Cc1ccc(-c2ccc(N(C)C)cc2)cc1)C3 +CNc1nc(Nc2ccc(C(=O)N3CCC(C(C)(C)O)CC3)cc2OC)ncc1Br +CCC(C)(C)C(=O)C(=O)N1CCCCC1C(=O)OCCCc1ccc(OC)c(OC)c1 +COc1ccc(Cn2c(CCc3ccccc3)nnc2C(NC(=O)c2ccccc2)c2c[nH]c3ccccc23)cc1 +CN=C(N)Nc1ccc(NC(=O)Nc2ccc(NC(N)=NC)cc2)cc1 +CN(C)CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(N)c1 +Cc1noc(C)c1-c1ccc2c(c1)C(c1ccccc1)(N1CCCC(O)C1)C(=O)N2 +O=C(NCc1ccccc1)OC1COC2C(OC(=O)c3cccnc3)COC12 +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCCCCNC(=O)C2CN(C)CCC2c2ccc(Cl)cc2)C1 +O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1)c1ccccc1F +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)c3ccncc3)CC2)cc1 +COc1cc2cc(c1OCCN1CCCC1)COCC=CCOCc1cccc(c1)-c1ccnc(n1)N2 +COCc1nc2c(C(=O)Nc3nc4ccccc4o3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +Cn1ccnc1C1Nc2cccc3c(=O)[nH]nc(c23)C1c1ccccc1 +O=C(CN1CCCCC1)Nc1cc(COC(=O)CN2CCCCC2)cc(Nc2ccnc3cc(Cl)ccc23)c1 +Nc1noc2cccc(C(=O)Nc3cccc(CNC(=O)Nc4ccc(F)c(F)c4)c3)c12 +N=C(N)c1ccc2[nH]c(-c3cc(C(CC(=O)O)C(=O)O)cc(-c4cccc(OC(F)F)c4)c3O)nc2c1 +CCNC(=O)OCc1c(COC(=O)NCC)c(-c2ccccc2)n2c1Cc1ccccc1C2 +CON=C(C)c1ccc(N2C(=O)c3n[nH]c(C(C)(C)C)c3C2c2ccccc2OC)cc1 +COc1ccccc1N1CCN(CCCOc2ccc3c(c2)SCC(=O)N3)CC1 +CCCN(CCC#N)c1nc(C)nc(N(CC)c2ccc(N(C)C)cc2C)n1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1cccc(CN(C)C)c1 +O=C(c1ccc(F)c(Cl)c1)N1CCC(F)(CNCc2ccc(Cl)cn2)CC1 +COc1ccc2nc3c(c(NCCCCCCNC(=O)C4(C)CCc5c(C)c(O)c(C)c(C)c5O4)c2c1)CCCC3 +O=C(O)Cc1cc(C2CCN(S(=O)(=O)c3cccc(Cl)c3)CC2)c2cc(F)ccc2c1 +Fc1ccc(C(OCCC2CCN(Cc3cc4ccccc4o3)CC2)c2ccc(F)cc2)cc1 +CNC(=O)c1cc2c(Oc3ccc(-c4ccccc4)cc3)cncc2s1 +Oc1nc2ccc(-c3ccc(F)c(F)c3)cc2n1C1CCCC1 +Cc1cc(NCc2c(Cl)cccc2Cl)c2cccc(C(N)=O)c2n1 +CC1CN(Cc2ccccc2)c2ccccc2C(C)N1C(=O)C1CCOCC1 +O=C(NC1CCNC1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(c1ccccc1)c1cc(Cl)ccc1NC(=O)C(c1ccc(F)cc1)N1CCN(CCO)CC1 +CC(C)(C)C1CCC(N2CCC(C(N)=O)(c3ccccc3F)CC2)CC1 +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2Cc2ccccc2C)c1 +O=C(O)CC(=O)NCN1CSC(=S)N(CCCCCCN2CN(CNC(=O)CC(=O)O)CSC2=S)C1 +COc1cc(-c2cc(C(=O)N3CCC(O)CC3)c3c(N)ncnn23)ccn1 +CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(-c3ccccc3OC)cc2F)CC1 +CC(C)CCCc1nc(-c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)no1 +O=C(Nc1nc2cc(F)ccc2n1C1CCC(CO)C1)c1cccc([N+](=O)[O-])c1 +CC(C)=CCC12OC(C)(C)C3CC(C=C4C(=O)c5c(O)cccc5OC431)C2=O +NCCCCN(CC1Cc2ccccc2CN1CC(=O)N1CCOCC1)C1CCCc2cccnc21 +NS(=O)(=O)c1ccc(SCCO)c([N+](=O)[O-])c1 +O=C(O)CSc1cc(NS(=O)(=O)c2ccc3ccccc3c2)c2ccccc2c1O +O=C(O)C=Cc1nc(CSc2c(Cl)cccc2Cl)ccc1OCCCc1ccccc1 +CC(Nc1cc(Nc2ccccc2)ncn1)C(Cc1ccc(Cl)cc1)c1cccc(Br)c1 +N#CC1CCC(Nc2ccc3ncc(-c4cccc(C(F)(F)F)c4)n3n2)CC1 +COc1cc2c(Nc3ccc4nc(N)sc4c3)c(C#N)cnc2cc1OCCCN1CCNCC1 +CNc1nc(-c2cc(OC)c(OC)c(OC)c2)c(-c2ccc(OC)cc2)s1 +O=C1OC2(CCC(c3nc4cc(OC(F)(F)F)ccc4[nH]3)CC2)CN1c1cccnc1F +CN1CCN(c2ccc(Nc3cc(NC4CC4)n4ncc(C=C5NC(=O)NC5=O)c4n3)cc2)CC1 +CC(C)CC(C(=O)NCC#N)c1cccc(-c2cccc(-c3csc(CN4CCNCC4)n3)c2)c1 +CCC1(c2nc3c(C(N)=O)cccc3[nH]2)CCCN1 +CCOc1ccc(S(=O)(=O)N(CC(=O)N2Cc3ccccc3C2C(N)=O)c2ccc(OC)cc2)cc1 +CC(C)Nc1c(C(N)=O)nnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc12 +CC(=O)OCC(Cc1cccc(C(=N)N)c1)C(C=Cc1ccccc1)NC(=O)c1ccc(-c2ccccc2)cc1 +CC(C)N1CCC(Oc2ccc(N3CCN(C(=O)c4ccc(C#N)cc4)CC3=O)cc2)CC1 +O=C(OCC(=O)N1CCC(c2ccccc2)=N1)c1ccc([N+](=O)[O-])s1 +CCOc1cc(C2NC(=O)N=C(c3cnn(C)c3)C2c2ccsc2)cc(C(=O)O)c1O +O=C(c1ccc2[nH]ccc2c1)N1CCC(N2C(=O)OCc3ccccc32)CC1 +Cc1cn(-c2ccc3n(c2=O)CCN(Cc2[nH]c4ccc(Cl)cc4c2Cl)C3=O)cn1 +CCN(CC)C(=O)Nc1cccc(C(Cc2ccncc2)c2ccc(OC)c(OC3CCCC3)c2)c1 +COc1ccc(C2C(C(=O)O)C(c3ccc4c(c3)OCO4)CN2CC(=O)NC(c2ccccc2)c2cc(C)ccc2C)cc1 +CCC(NC(=O)N1CC(=O)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)cc1 +O=C(O)CC(NC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1)c1cncc(C=Cc2cccc(OCCF)c2)c1 +CC(C)N(c1ccc(Oc2cccnc2)nc1)S(=O)(=O)c1ccc2ccccc2c1 +CC(C(O)c1ccccc1)N(C)S(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2)c(F)c1 +O=C(C=Cc1ccc2c(c1)C(=O)N(CCc1ccccc1)C2=O)NO +CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(OC(F)(F)F)cc3)[nH]2)CC1 +O=C(C1=C(O)C(=Cc2cccc(OCCN3CCCC3)c2)CCC1)c1ccccc1 +CCN1CCCC1C(=O)Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1 +CN1CCN(C2=Nc3cc(Cl)ccc3Oc3ncccc32)CC1 +O=C(C=Cc1ccc(O)c(O)c1)c1ccccc1-c1cccs1 +N=C(N)c1cccc(C(=CC(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)Cn2cnnn2)c1 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc5c4OC(F)(F)O5)c3)cc12 +CCC(N)C(=O)NC1CCCCC2CCC(C(=O)NC(c3ccccc3)c3ccc4ccccc4c3)N2C1=O +COC1CCN(c2nccc(Nc3cc4c(cn3)nc(C)n4C(C)C)n2)CC1F +Cc1nn(C(C)C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nnnn4C)CSC23)cc1Cl +Clc1ccc2c(c1Nc1ncnc3cc(OCCc4ccncc4)cc(OC4CCOCC4)c13)OCO2 +CN(CCCCN1C(=O)CCc2ccccc21)Cc1ccccc1 +COc1cc(-c2c3c(cc4c2[nH]c2ccccc24)COC3=O)cc(O)c1O +CN1CC(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)CC2c3cccc4[nH]cc(c34)CC21 +COc1cc(C2c3cc4c(cc3C(Nc3ccc(F)cc3)C3COC(O)C23)OCO4)cc(OC)c1O +COc1ccccc1C(CC(=O)O)NC(=O)CCCCc1ccc2c(n1)NCCC2 +CC(C)(C)OC(=O)NC(Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1CC1CC1 +CCOc1cc(=O)n(C)cc1-c1cc(N(CCc2ccccc2)S(=O)(=O)CC)ccc1Oc1ccc(F)cc1F +O=S(=O)(c1ccc(F)cc1)N1c2ccccc2-c2n[nH]cc2C1C1CC1 +CCCN(CCCCN1CCN(c2ccc(-c3cccc(O)c3)cc2)CC1)C1CCc2nc(N)sc2C1 +CCCN(CC1CC1)c1nc(C)nc(N(CC)c2ccc(N(C)C)cc2C(F)(F)F)n1 +CCNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O +CC(=O)Nc1ccc(-c2ccccc2)n(CC(=O)NC(C(=O)C(F)(F)F)C(C)C)c1=O +NC(=O)C1(c2ccccc2)CCN(C(=O)NC2C3CC4CC(C3)CC2C4)CC1 +OC1CCc2cccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 +NC(=O)Nc1ccc(Nc2cccc(C(F)(F)F)c2)cc1 +O=C(NCCS)C(Cc1cc(Br)cc([N+](=O)[O-])c1)=NO +CCOc1ccc(-n2c(C)c3c(C)nnc(-c4ccc(C)cc4)c3c2C)cc1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(C(F)(F)F)cn2)c1 +O=c1c(-c2ccccc2F)c2ccccn2c(=O)n1CCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1 +Cn1c(SCCC(=O)O)nc2c(Br)c(Br)c(Br)c(Br)c21 +Cc1cc2c3c(c1)C(c1ccccc1)=NC(NC(=O)c1cc(Cl)c(N)c(Cl)c1)C(=O)N3CC2 +COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(C)c2c1 +O=c1[nH]c(Cc2ccccc2-c2ccco2)nc2c1cnn2C1CCOCC1 +Cc1cccc(C)c1Oc1ccc(C(=O)N(Cc2ccccc2)Cc2ccc(C(=O)O)cc2)cc1 +Cc1ccc(-c2noc(C3CC(n4cncn4)C3)n2)cc1NC(=O)c1cnc2ccccn12 +Oc1ccc2c(c1)C1(CCCCc3ccccc3)CCN(CCc3ccccc3C(F)(F)F)CC1O2 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C(F)(F)F)nn3)c2)c2cnccc21 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(CNCC4CC4)o3)nc2n1 +COc1cc(-c2cccc(C(F)(F)F)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ncccn3)c(F)cc21 +NC1(c2ccc(-c3ncc4ccccc4c3-c3ccccc3)cc2)CCC1 +c1cc(C2CNCCO2)ccc1Nc1ccc(C2COC2)cn1 +CNC(=O)Nc1ncc(SC2CCOCC2)cc1Oc1cccnc1C +Cc1nc(NC2CCCOC2C)nc(-n2ccnc2C)c1[N+](=O)[O-] +Cc1c(CN(CCCCc2ccccc2)C2CCN(C(=O)c3cccc4ccccc34)CC2)c(=O)n(-c2ccccc2)n1C +Cc1cc2nc(CC(N)C(=O)O)c(CP(=O)(O)O)nc2cc1C +Cc1cccc(C)c1C(=O)N1CCC(N2CCC(N(Cc3ccccc3)C(=O)C3CC3)C2)CC1 +CCOC(=O)N1CCC(N=C(NC#N)N2CCC(=C3c4ccc(Cl)cc4CCc4cc(Br)cnc43)CC2)CC1 +COc1ccc(Nc2nc(-c3cccc(C(=O)Nc4ccc(-c5ncc[nH]5)cc4)c3)cn3ccnc23)cc1OC +CCCOCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)c(C)c12 +C=C(Br)C(=O)Nc1cccc(C=C2CCCC(=Cc3cccc(NC(=O)C(=C)Br)c3)C2=O)c1 +CCCn1nc(-c2ccc(OCCCN3CCCC3C)cc2)c2sccc2c1=O +Cc1ccc2c(c1Br)C(=NNC(=O)Cc1ccc(O)cc1)C(=O)N2 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2cnccn2)CC1c1ccccc1 +O=C(N=S(=O)(CCCO)CCCO)c1cncc(C#Cc2cccc(NC(=O)c3ccc(Cl)c(C(F)(F)F)c3)c2)c1 +CCc1nc(N)nc(-n2c(Nc3cccc(O)c3)nc3ccccc32)n1 +CCN1C(=Cc2sc3ccccc3[n+]2C)C=Cc2ccccc21 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+O=c1cc(-c2ccccc2)oc2cc(OCCCCN3CCN(CCNc4c5c(nc6ccccc46)CCCC5)CC3)ccc12 +CCOc1cccc(CN2CCN(Cc3cc4ccccc4o3)CC2)c1 +Fc1ccc(-c2ncn(C3CCNCC3)c2-c2ccnc(Oc3ccc(-c4ccccc4)cc3)n2)cc1 +CCCC(CC)n1ccc2cc(C(C)=CC(=O)Nc3ccccc3OCCCC(=O)O)ccc21 +COc1cc2c(ccn2-c2cccc3ncccc23)c(OC)c1OC +CCc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(=O)(=O)CC)cc2)cn1C(C)C +Nc1cnc(-c2ccc(-c3ccc(C(F)(F)F)cc3CN3CCOCC3)cc2F)cn1 +CN1CCCCC1Cn1cc(C(=O)c2cccc3ccccc23)c2ccc(I)cc21 +COCC(=O)N(C)Cc1cccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)c1 +CC1=C(F)CN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CC4CC3CO4)n2)C1 +COc1ccc(CCN(C)CCCOc2ccc(S(=O)(=O)c3c(C(C)C)oc4ccccc34)cc2)cc1OC +CC(c1ccccn1)N(CCCCN)Cc1ncccc1C(C)(C)C +CCNC(=O)c1ccc(Oc2cc(NC(=O)N3CCC(O)(CC(CC)CC)CC3)cc(Oc3ccc(F)cc3)c2)cc1 +CC(C)(C)c1ccc2ncn(CC(=O)CC3NCCCC3O)c(=O)c2c1 +COc1ccc(CN2CC3CCC(=O)C2CN3CC=C(C)C)cc1 +CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CCN(c2ncccn2)C3)cc1 +C=COC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)CCCNC(=O)OCc1ccccc1)C(C)C +Cc1ccccc1C1CCc2c(C(=O)N(C)C)cn3c(C)c(C)nc3c2O1 +CCCc1cc(N)c2cc(NC(=O)c3ccc(-c4ccc(C(F)(F)F)cc4)cc3)ccc2n1 +COC(=O)C1=C(C)CC(C)=C(C(=O)OC)C1c1ccc(Cl)c(C(F)(F)F)c1 +COc1ccc(-c2ccc(OCc3cc(C(=O)NS(=O)(=O)c4ccccc4C)oc3C)cc2)nc1 +O=C(O)CCN1C(=O)C(=Cc2ccc(Cl)cc2Cl)SC1=S +CCC(CC)C(=O)OC1C(C)=CC23C(=O)C(C=C(CO)C(O)C12O)C1C(CC3C)C1(C)C +CCCCC(NC(=O)OC(Cn1cnc(-c2ccc(C(F)(F)F)cc2)c1)C(C)(C)C)C(=O)C(=O)Nc1nccs1 +CCN(CC)CC(Cc1ccccc1)Nc1ccncc1S(=O)(=O)NC(Cc1ccc(N)cc1)C(=O)N1CCC(CCF)CC1 +O=C(c1ccc2ncccc2c1)N1CCC(N2CCC(Cc3ccc(Cl)c(Cl)c3)C(CF)C2)CC1 +O=C(Nc1ccc(-c2ccc(Cl)c(Cl)c2)cc1)C1=C(O)c2ccc(O)cc2S(=O)(=O)N1 +CCOc1ccc(Cc2cc3c(cc2Cl)OCCCCOCC2OC3C(O)C(O)C2O)cc1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(=O)[nH]c2)c1 +N#Cc1ccc(Cl)c(Oc2ccc(S(=O)(=O)Nc3ccc(F)cn3)cc2C#N)c1 +CN1CCC(c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1=O +COC12CCC3(CC1COCc1ccccc1)C1Cc4ccc(NC(C)=O)c5c4C3(CCN1C)C2O5 +Cc1cc(C)cc(C(CC(C)C)NC(=O)c2cc(COc3ccccc3F)ccc2CCC(=O)O)c1 +O=C(C=Cc1ccc2c(c1)C(=O)CC1(CCN(C(=O)c3ccccc3)C1)O2)NO +Cc1cc(-c2ccc(C(=O)Nc3ccccc3C(=O)O)cc2Oc2ccccc2)ccc1F +OC(COc1cccc2[nH]ccc12)CN1C2C=C(c3ccc4ccccc4c3)CC1CC2 +Cc1cc(C)nc(OCC(=O)Nc2cc(-n3nc(C)cc3C)nc(-c3ccc(C)o3)n2)n1 +CC(C)c1cc(C(=O)N2CCC(NC(=O)C(C)(C)C)C2)n[nH]1 +COC(=O)CCCCCCCNC(=O)c1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)cc1 +O=C(Nc1ccc(-n2ccc3c(NC(=O)c4ccccc4)nccc32)cc1)c1ccc(N2CCOCC2)c(C(F)(F)F)c1 +O=C1Nc2ccc(-c3csc(C4CCNCC4)n3)cc2C1=Cc1cc2ccccc2[nH]1 +CCOc1c(C(C)=CC=CC(C)=CC(=O)O)cc(C(C)(C)CC)cc1C(C)(C)CC +CC(C)CC(NC(=O)c1ccc(-c2ccccc2)cc1)C(=O)NC1COCC1=O +Cn1c(-c2ccc3nccnc3c2)c(-c2ccc3nonc3c2)c(=O)n1C +O=C(c1ccccc1)C1CCN(CC(O)COc2cccc3[nH]c4ccccc4c23)CC1 +O=C(NC1CCNC1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +Oc1ccc(CCNc2nc(SCCOc3ccc(Cl)cc3)nc(N3CCNCC3)n2)cc1 +CS(=O)(=O)N1CCCC(n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)C1 +CNC(=O)C(Cc1ccccc1)NC(=O)C(CCCCCCc1ccccc1)CC(=O)NO +N=C(NO)c1cccc(N2C(=O)N(c3cccc(C(N)=CO)c3)C(Cc3ccccc3)C(O)C2CCc2ccccc2)c1 +O=C(NC1CCCCC1)c1ccc(OCc2ccccc2)nc1 +O=C1Nc2ccc(S(=O)(=O)Nc3ccc(N4CCOCC4)cc3)c3cccc1c23 +CN1CCN(c2ccc(-c3ccc4[nH]c5nccc(-c6ccc(C(=O)c7ccccc7)cc6)c5c4c3)cc2)CC1 +N#CNC(=NC1CC1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +COc1cccc(CCn2c3c(c4c2-c2ccccc2C4=O)C(=O)CCC3)c1 +N#CC1CCCCC1n1cc(C(N)=O)c(Nc2ccc(F)c(Cl)c2)n1 +CS(=O)(=O)c1ccc2c(c1)CCC1(CCN(C(=O)c3ccc(C(F)(F)F)cc3)CC1)O2 +CCc1ncnc(-c2ccc(C(=O)N(C)OC)c(F)c2)c1C#Cc1ccc(N)nc1 +CCOc1cc(CN2CCC(NC(=O)c3cncc(C)c3)CC2)cc(OCC)c1F +CCCNC(=O)Nc1cccc(-c2ccc(CC(NS(=O)(=O)c3cccc(Cl)c3Cl)C(=O)O)cc2)c1 +Cc1c(-c2nnc(C(C)(C)C)s2)nc(-c2ccccc2Cl)n1-c1ccc(Br)cc1 +O=C(NC1CCN(Cc2ccccc2)C1)c1cccc(-c2cccs2)c1 +CCN1CCN(Cc2cnc(-c3ccc(C(=O)Nc4ccccc4N)cc3)c(F)c2)CC1 +CCN(CC)CCCOc1cc2c(cn1)C(c1ccccc1)CN(C)C2 +CC(=O)c1c(-c2ccccc2)nn(C)c(=O)c1NCCN1CCN(c2ccccc2Cl)CC1 +CCc1cc(-c2ccccc2)cc(CC)[n+]1CC(=O)OCCc1ccc(S(N)(=O)=O)cc1 +CC(NC(=O)C1CC1)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1NC1CCC(O)CC1 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5ccc(F)cc5F)nc4)cccc3c2F)CS1(=O)=O +CN(C)CCn1cnnc1-c1cc(Oc2ccc(NC(=O)NN=Cc3c(Cl)cccc3Cl)cc2F)ccn1 +CCS(=O)(=O)c1ccc(Oc2cc(OC(C)CO)cc(-c3nccc(=O)[nH]3)c2)cc1 +CC(C)c1nn(-c2nc3ccccc3s2)c(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +CC(F)(F)Cn1cnc2c(-c3ccc(Cl)cc3)n(-c3ccccc3Cl)nc2c1=O +Cc1cc(-c2ccc(CO)o2)cnc1C1(F)CCN(C(=O)Nc2ccc(C(F)(F)F)c(Cl)c2)CC1 +Fc1ccc(CCCN2CCC(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 +CCCCCCCCCCCCCCC1=C(O)C(=O)C=C(OC)C1=O +CC(C)S(=O)(=O)N1CCC(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CC1 +Cc1[se]c(C=C2C(=O)Nc3cc(-c4cccc(O)c4)ccc32)cc1C(=O)NCCN(C)C +Cc1nc2ccc(F)c(-c3cc4c([nH]3)CCNC4=O)c2nc1NC1(C)CC1 +O=C(Nc1ccc(C(F)(F)F)cc1)N1CCCC1c1ncnn1Cc1ccc(Cl)cc1 +O=C(OC1(C2COCC(CC3CC3)N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CC2CCC(C1)N2CCO +CCCC(CCC)C1C(C(=O)c2ccc(CO)cc2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +ON=CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CCCCCc1ccc(C(=O)OC2CCC(NC(=O)C(OC)C(O)C(O)C(O)C=CC(C)(C)C)C(=O)NC2)cc1 +N#Cc1ccc(OCCCN2CCC(C(O)(c3ccccn3)C3CCCC3)CC2)cc1 +CCN(CCO)CCCOc1ccc2c(Nc3cc(CC(=O)Nc4cccc(F)c4)[nH]n3)ncnc2c1 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)(F)C2)CCN1Cc1ccc(Cl)c(Cl)c1 +O=C(O)C1CC(NC(=O)N(c2ccccc2)c2ccccc2)c2c(Cl)cc(Cl)cc2N1 +CCc1nc(-c2ccccc2)c(-c2ccccc2)n1CCCCCCCC(=O)OC +O=C(NCc1ccno1)c1cnc(Oc2ccc3c(c2)CCC(c2cccc(F)c2)O3)s1 +CN(C)CC(Cc1ccccc1)c1cc(OCCNS(=O)(=O)c2cn(C)cn2)ccc1F +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)cc1C(=O)O +Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(=C(F)c2cnc3ccccc3c2)CC1 +O=C1Cc2c([nH]c3ccc(F)cc23)-c2ccccc2N1 +Cc1cc(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C(C)C)n2)c(OC2CC2)cc1C1CCN(C(C)C)CC1 +N#CCCn1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)cc4)CCC3)no2)cn1 +CC(=O)NC(Cc1ccccc1)C(=O)OCc1cc(C)cc(C)c1 +O=C(CCCN1CCCC1)Nc1n[nH]c2nnc(-c3ccccc3)cc12 +CN(C)c1ccc(C(c2c(O)oc3ccccc3c2=O)c2c(O)oc3ccccc3c2=O)cc1 +CCOC1CN(c2cccc(-c3cccc(C)c3OCc3cc4c(c(OC)c3)CN(C3CCOCC3)CC4)n2)CCC1C(=O)O +COC(=O)c1cccc2c1nc(Nc1c(C)cccc1Cl)c1cncn12 +OCc1cc(C(O)CNCCc2ccc(NCC(O)c3ccc(O)cc3)cc2)ccc1O +COc1ccccc1C1c2c(n[nH]c2C(C)C)C(=O)N1c1ccc(-c2ccsc2)c(CO)c1 +Fc1cccc(CNc2n[nH]c3ccc(-c4cn(Cc5ccccc5)nn4)cc23)c1 +CCOc1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +O=C(NCCc1ccccc1)Nc1ccc2cc(C(=O)NC3CN4CCC3CC4)sc2c1 +OCC#Cc1cn2c(-c3ccc(-c4cnc(C5CC5)[nH]4)cc3)cnc2c(NCCCCO)n1 +Cc1ccc(OCC(=O)N(Cc2cccs2)C(C)C)cc1 +COc1cc(Cc2nc(-c3ccccc3)c[nH]2)cc(OC)c1OC +CC(C)NC(=O)c1cc(F)ccc1CNC(=O)c1nc(C(C)(C)C)n(C)c(=O)c1O +CN1CCN(c2ccc(-c3cncc(-c4ccc(C(=O)NS(C)(=O)=O)cc4)n3)cc2)CC1 +Cc1cc2scnc2cc1-c1ccc(C(=O)Nc2ccccc2F)s1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=O)C(C)(C)C)CCO1 +COc1cc(O)c2c(=O)cc(-c3ccc(O)c(O)c3)oc2c1O +CC(=O)NC1CC2(CCN(Cc3ccc4[nH]c5ccccc5c4c3)CC2)c2ccccc21 +CCCCN(CC)c1nc(C)nc2c1n(C)c(=O)n2-c1ccc(C(C)C)cc1Br +CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCN2C3=O)CC1 +O=C(CCN1CCCC(n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)C1)N1CCC(F)(F)C1 +COc1cccc(CNC(=O)c2cn(C)c3nc(-c4cn[nH]c4)ccc23)c1 +CC12C=CC(=O)C=C1CC(Cc1ccccc1)C1C2CCC2(C)C(=O)CCC12 +CCC(C(=O)NC(CC(=O)O)C(=O)CNCCCc1ccccc1)n1cccc(NC(=O)c2ccc3ccccc3c2)c1=O +O=C(NC1CCCCC1O)c1cn(Cc2ccc(-n3cccn3)cc2)c2ccccc12 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-c3nc4ccccc4[nH]3)ccc(F)c12 +COC(=O)c1ccccc1-c1ccc(CNc2ncccc2NC(=O)CC(F)(F)F)cc1 +N=C(N)c1ccc(-c2cc(-c3cncc(C(=N)N)c3)on2)cc1 +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4ccc(Cl)nc4c3)CC1)C2 +CC(C)(C)c1cccc(CNC2C[S+]([O-])CC(Cc3cc(F)c(N)c(OC(CO)C(F)(F)F)c3)C2O)c1 +Cc1ccc(C2=C(NC(=O)c3cnccn3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +CN(CCc1ccccc1)C(=O)c1cc(N)c2nc(-c3ccc(Br)o3)nn2c1 +CCCN(C(=O)OCc1cccc(C)c1)C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2ccccc2)CC1 +O=C(O)c1ccccc1C(=O)C=Cc1ccc(OCc2ccc3ccccc3n2)cc1 +COCC(C)n1c(-c2cnc(OC)nc2OC)nc2c1C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +Cc1nc2ccccc2nc1OCc1cc(OC2CCOCC2)nc(N2CCCC2)n1 +O=C(NC1CCN(CCOc2cccc(-c3ccccc3)c2)C1)c1cccc(F)c1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCC3CCOCC3)c12 +Fc1ccc(C(OCCC2CCN(CCc3ccccc3)CC2)c2ccc(F)cc2)cc1 +C(#Cc1cc(-c2n[nH]c3c2Cc2cc(CN4CCSC4)ccc2-3)cs1)COc1ccccc1 +CS(=O)(=O)N1CC2(CCN(C(=O)Nc3cn(-c4cccc(F)c4)cn3)CC2)c2ccccc21 +COc1cc(C=CC(=O)NO)ccc1OCC(Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1F +COc1cc(-c2nc(-c3cc(C)nc(C(F)F)c3)c3n2CC(C)OCC3)ccc1OC(F)F +NC(CC(=O)N1CCCN(c2ncccn2)CC1)Cc1cc(F)c(F)cc1F +Cc1noc(C)c1C(=O)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +N#Cc1ncc2nc1OCCC=CCOc1ccc(OCCCN3CCOCC3)cc1NC(=O)N2 +CC1(c2nc(NC(=O)c3ncc(OCCF)nc3N)ccc2F)N=C(N)OCC1(F)F +Cc1cccc(CNc2nc(C)nc(C(F)(F)F)n2)c1 +CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(-c4cnn(CCOC)c4)c2)CC3)n1 +O=C(O)CCCC=CCC1C2CCC(C2)C1NS(=O)(=O)Cc1ccccc1 +CC(C)n1ncnc1-c1cn2c(n1)-c1cnc(N(C)CC(N)=O)cc1OCC2 +CN(C)CC(c1ccc(C(F)(F)F)cc1)N1CCN(c2ncnc(N)c2Br)CC1 +Oc1ccc2c3c1OC1C(O)C=CC4C(C2)N(C2CCCCCC2)CCC341 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccnc(F)c3)cc2s1)S(=O)(=O)CCC(F)(F)F +CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(C)c3)ncn2)c1 +Cc1cc2nc(N)[nH]c(=O)c2n1Cc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +CC(C)(C)OC(=O)N1CCC(c2cccc(Nc3nc4c(-c5ccc(S(C)(=O)=O)cc5)cccn4n3)c2)C(O)C1 +CC1CNC(=O)c2[nH]c3ccc(C(=O)Nc4ccc(C(N)=O)nc4)cc3c21 +Cc1ccccc1-c1nc(-c2nc3ccccc3[nH]2)c(N2CCN(C(=O)Cn3cnc4cccnc43)C(C)C2)s1 +O=C(O)c1sc(-c2ccccc2)cc1N1C(=O)CCCC1C1CCCCC1 +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(S(C)(=O)=O)c3)cc2N=C(N)C1 +CNS(=O)(=O)Nc1cccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1C +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(N3CCN(C)CC3)cc12)C(=O)O +COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(=O)OC)CC2)C1c1ccc(F)c(F)c1 +COc1ccc(CC(=O)OCC(=O)Nc2c3c(nc4ccccc24)CCCC3)cc1OC +CCC(CO)Nc1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +O=C(Cc1ccccc1)Nc1nnc(OC2CCN(c3nnc(NC(=O)Cc4ccccc4)s3)C2)s1 +CCCc1c(COc2ccc(C(C)c3nnn[nH]3)cc2)ccc(C(C)=O)c1O +CC(=Cc1nc(C(=O)O)c[nH]1)c1cc2c(cc1C)C(C)(C)CCC2(C)C +O=c1cc(C2CCCCC2)oc2ccc(OCCCCCCN3CCC(O)CC3)cc12 +Cc1cn(C2CC(N=[N+]=[N-])C(COP(=O)(O)OCCOc3ccc4ccccc4c3)O2)c(=O)[nH]c1=O +COc1cc(OC)cc(C(=O)N(C)CCCNc2ccnc3cc(Cl)ccc23)c1 +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)C2C4CC6CC(C4)CC2C6)CCC3(O)C1C5 +Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(C(F)(F)F)cc4)c3Cl)cccc2s1 +O=C(Nc1ccc2c(c1)CN(C(=O)c1ccccc1)C2)N1Cc2ccccc2C1 +CC(C)COC(=O)C(Cc1ccccc1)NP(=O)(COC1C=C(F)C(n2cnc3c(N)ncnc32)O1)Oc1ccccc1 +CC(C)CCN1C(=O)C(NC(=O)Nc2ccc(Cl)cc2)C(=O)N(CCN2CCOCC2)c2ccccc21 +CC(C)(C)c1nc(-c2ccn[nH]2)c2c(N)c(C#N)c(N)nc2n1 +CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(N)Cc2ccc(F)cc2)C(CCNc2ccccn2)C1=O +CC(=NOCc1ccc(C2CCCCC2)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cc1 +CCCCCC1=CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 +CCCCCCCCCCCCCCCC(=O)OC(COC(=O)CNCCCOCCOCCOCC)CSCC(N)C(=O)NC(CO)C(=O)O +O=C(Nc1ccncc1-c1ccccc1)N1CCN2C(=O)N(C3CC3c3ccccc3)C(=O)C2C1 +CC(C)c1ccc(-n2nnnc2C(NCC2CCCCC2)c2c(C(=O)O)[nH]c3cc(Cl)ccc23)cc1 +O=C(Nc1cc(-c2ccccc2)[nH]n1)c1ccc2cc3n(c2c1)CCCNC3=O +COc1ccc(Cn2c(CCc3ccccc3)nnc2C(NC(=O)C(C)(C)N)c2c[nH]c3ccccc23)c(OC)c1 +C=C(Cl)COc1cc(-n2nnc3c(cnn3C)c2=O)c(F)cc1Cl +Cn1c(-c2nnc(N)s2)nc(Br)c1[N+](=O)[O-] +COC(=O)C(Oc1nc(OC)cc(OC)n1)C(C)(Oc1ccc(C(C)C)cc1)c1ccccc1 +O=C(Nc1nc2cccc(-c3ccc(NS(=O)(=O)C4CC4)cc3)n2n1)C1CC1 +CCn1cnc(-c2cc3nccc(Oc4ccc(NC(=S)NC(=O)Cc5ccccc5)cc4F)c3s2)c1 +CN(C)C=CC(=O)c1c[nH]c2ccc(-c3cncc(NCCN(C)C)n3)cc12 +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccc(Cl)cc1Cl +COc1cc(N(CCCNCC(F)(F)F)c2ccc3ncc(-c4cnn(C)c4)nc3c2)cc(F)c1F +COc1cccc(F)c1CN1C(=O)N(c2cnn(Cc3c(C)noc3C)c2)C(=O)C1(C)C +CC(C)(C)c1cc(C=C2CCN(c3cccnc3)S2(=O)=O)cc(C(C)(C)C)c1O +CCN(CC)CCOc1ccc(Nc2ncc3cc(-c4ccccc4)c(=O)n(C)c3n2)cc1 +CCc1c(-c2ccccc2)ncn1CCCOc1cccc(C)c1NC(=O)NCCC(C)C +Cn1nc(C(C)(C)C)cc1C(=O)NC(Cc1cccc(-c2nncs2)c1)C(=O)NCC#N +Cc1ccc(-c2ncc(Cl)cc2-c2ccc(S(N)(=O)=O)cc2)cn1 +NC1=NC(c2cccc(OCc3ccccc3)c2)N(c2ccc(Cl)cc2)C(N)=N1 +Cc1cc(C(=O)Nc2cccc(C(C)N3CCC(C(=O)NC4CCCCC4)CC3)c2)ccn1 +O=C(O)CC1C(=O)N(Cc2ccc(Br)cc2F)C(=O)c2ccc(F)cc21 +NNC(=O)c1[nH]c2ccc(S(N)(=O)=O)cc2c1-c1c(F)c(F)c(F)c(F)c1F +C=CCC1(C(=O)Nc2cccc(OC(=O)N(C)C)c2)CCN(c2ncnc3[nH]cc(C)c23)CC1 +CC(C(=O)NC1CC1)c1ccc(OC2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 +CNc1ccc(Nc2ncnc3cc(-c4ccccc4)sc23)cc1 +Cc1ccc(C(=O)NC2CCOCC2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +Cc1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CCCNCC3)n2)sn1 +Cc1ncc([N+](=O)[O-])n1CCOC(c1ccccc1)c1cccnc1 +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(C)c(OC)sc4c3=O)CC21 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1cc(C)ccc1Cl)CC2 +O=C1CCc2ccccc2N1CCCCN1CCN(c2ncccn2)CC1 +CCc1c(Sc2cc(C)cc(C)c2)n(CCC2CCCC2)c(=O)[nH]c1=O +O=C(NCC(c1ccc(C(F)(F)F)nc1)N1CCOCC1)C1COc2ncccc21 +O=C(NCc1ccc(F)cc1)c1c(Nc2ccc(-c3ccccc3)cc2)[nH]c(=O)n(O)c1=O +CN(C)CCCN=C1CC(c2ccc(Cl)cc2Cl)Cc2nc3ccc(Cl)cc3c(O)c21 +CNCCNc1ccc2c(cc1=O)C(NC(C)=O)CCc1cc(OC)c(OC)c(OC)c1-2 +COc1cccc(C=c2[nH]c(=O)c(=Cc3nc[nH]c3C(C)(C)C)[nH]c2=O)c1[N+](=O)[O-] +CCCN(CCC)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(Cl)cc12 +CNC(=O)c1ccc(F)c2c(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12 +CC(Nc1nccc(N(C(=O)Nc2ccccc2Cl)c2ccccc2)n1)C(C)(C)O +CC(C)c1cc(CN(C)C(=O)NCC23CC4CC(CC(C4)C2)C3)no1 +Cc1noc(-c2ccc3c(c2)c2c(n3CCCSc3cc(F)cc(F)c3)CCCC2)n1 +O=C(NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1)c1ccccc1 +COc1cc(Cn2cnc3cc(C#CCCO)cnc32)ccc1OCc1ccc(C(F)F)nc1 +CC1CCCN1CCc1ccc(C2=CCC3CN(Cc4ccccc4)CC23)cc1 +O=C(NC1CC1)c1ccc(CN(C2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 +CC(c1ccc(Cl)c(Cl)c1)C(NC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)C(=O)O +NCc1ccnc(Oc2cccc(C(=O)Nc3ccc(C(=O)O)cc3)c2)c1 +FC(F)(F)C(F)(F)CNCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +COc1ccccc1N1CCN(Cc2ccc(CN(C(C)C)S(C)(=O)=O)n2C)CC1 +Clc1ccc2c(NCc3nc(-c4ccccc4)cs3)ccnc2c1 +O=C(CC(CCCc1ccc(F)cc1)C(=O)NC(CC1CCCCC1)C(=O)NCCc1ccccc1)NO +CCC(=O)c1c2c(nc3ccccc13)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC +CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2ccc(OCC(F)F)c(C(=O)Nc3ccc(Br)cc3)c2)c1 +COC(=O)C1=C(Nc2ccc(OC)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O +C=CC(=O)Nc1cccc(N2C(=O)N(C)Cc3cnc(Nc4ccc(N(C)C)cc4OC)nc32)c1 +NS(=O)(=O)c1ccc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)cc1 +COc1ccc(-c2nc(CSc3ccc(OCC(=O)O)c(C)c3)oc2-c2ccc(OC)cc2)cc1 +CC(C)n1c(=O)n(C(=O)NC2CC3CCCC(C2)N3C)c2ccccc21 +Cc1cc(Oc2ccc3cc(C#N)ccc3c2Br)nc(Nc2ccc(C#N)cc2)n1 +COc1ccc(S(=O)(=O)Nc2cc(-c3cnc4nc(N)nc(C)c4c3)cnc2OC)cc1 +COc1ccccc1N1CCN(CCNC(=O)OC(C)(C)C)CC1 +COc1cc(O)cc(N(CCN)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CSc1nn(-c2c(Cl)cc(Cl)cc2Cl)c2nc(CCCCCO)[nH]c(=O)c12 +N#CCNC(=O)CNC(=O)C(Cc1ccccn1)NC(=O)Cc1cc(Cl)cc(Cl)c1 +CCCC(CCN1CCCC(Cc2ccc(F)cc2)C1)NC(=O)Nc1cc(-c2nnnn2C)cc(C(C)(C)O)c1 +COc1cc2c(cc1OC)C(c1ccccc1[N+](=O)[O-])N(CCOc1ccccc1)CC2 +COC1CCN(Cc2ccc(C#Cc3ccc4c(c3)CCC4NC(C(=O)NO)C(C)O)cc2)CC1 +O=C(O)c1cccc2c1nc(Nc1ccccc1Cl)c1ccsc12 +O=Cc1cc(-c2ccc(C(=O)N3CCOCC3)cc2)cc(C(F)(F)F)c1O +Cc1nc2ccccc2c(Nc2ccc(N3CCN(C)C(C)C3)cc2)c1C(C)O +COc1cccc2c1c(C(=O)C=C(O)C(=O)O)cn2Cc1ccccc1F +O=C(c1nc2cccc(Cl)c2[nH]1)N1CC(c2nccnc2-c2cccnc2)C1 +CC(c1ccc2c(c1)CCO2)N(Cc1ccc(OCCN2C(=O)CN(C)C2=O)c(Cl)c1)CC1CCC(C(=O)O)CC1 +Cc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C2CCCO2)n1 +CN(C)CCN(CCNCCc1ccc(O)c2[nH]c(=O)sc12)C(=O)CCOCCc1ccccc1 +Cc1[nH]c(-c2ccccc2Oc2ccccc2)cc1C(N)=O +COc1cccc(NC(=O)c2ccc(Nc3nc(Nc4ccc(O)cc4)ncc3F)cc2)c1 +COc1ccc(CN2CCCN(CC3CCCCC3)CC2C)cc1 +CC1CC2C(OC(=O)NC(Cc3ccccc3)C(O)CN3CC4CCCCC4CC3C(=O)NC(C)(C)C)COC2O1 +Cc1nnc(SCc2nc(-c3ccc(Cl)cc3)no2)n1-c1ccc(F)cc1 +COCCNCc1c(C(=O)NC2CCCC(O)C2)noc1-c1ccc(C(F)(F)F)cc1 +COc1cc(-c2onc3c2CCCN3Cc2ccc(F)cc2)ccc1-n1cnc(C)c1 +CN(C)Cc1ccc(CCN2CCn3nc(C(=O)Nc4ccc(F)cc4)cc3C2=O)cc1 +CCNc1ncc2nc(Nc3ccccc3F)n(C3CCCC3)c2n1 +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(O)c1 +CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CCC(C)=CC21 +CN(C)CCCN1c2ccccc2CCc2ccc(C#CCOCCCOc3cccc4ccccc34)cc21 +CNC(=O)C(NC(=O)C(CC(C)C)C(NC(=O)c1cccnc1)C(=O)NO)C(C)(C)C +[H]C([H])([H])OC(=O)c1cc2c3ccccc3nc-2c[nH]1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2Cc3[nH]ncc3C1CC(c1nc[nH]n1)C2 +NC(=NO)c1ccc(NC(=O)CCNCCc2ccccc2)cc1 +O=c1cc(NCCCNCc2ccc(Cl)c(Cl)c2)[nH]c2ccccc12 +CN1CCC(c2ccc(CN(C)Cc3ccc(Cl)cc3)cc2)CC1 +CCOC(=O)N1CCC(c2ccccc2OC)(S(=O)(=O)c2ccc(Cl)cc2)CC1 +COc1ccc(CNc2c(CO)cnc3c(N(C)C)cc(C#N)cc23)cc1Cl +O=C1c2ccccc2C(=O)c2c(-c3ccc(OCCN4CCOCC4)cc3)noc21 +COC1CCC2(CC1)Cc1ccc(-c3cc(F)ccc3C)cc1C21N=C(N)N(C)O1 +O=C(Nc1cccc(F)c1)c1c(O)c2ccc(F)cc2[nH]c1=O +O=C(O)CC(NC(=O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O)C(=O)O +CCN1CCN(C(=O)Nc2cccc3ccccc23)CC1C(C)Nc1nccc(-n2cnc3ccccc32)n1 +O=C(c1ccc(Oc2ncccc2-c2ccnc(F)c2)cc1)c1nc2ccccc2[nH]1 +COC(=O)c1cccc(-c2ccc(O)c(C=O)c2)c1 +Cc1sc(NC(=O)Cn2nc(C(F)(F)F)c3c2CCCC3)c(C(N)=O)c1C +COc1cc(C(=O)c2ccn(-c3cccc(N)c3)c2)cc(OC)c1OC +CCOC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NCC#N +CCc1ccc(-n2c(C(CC)N(CCc3ccccc3)C(=O)c3cc(OC)cc(OC)c3)nc3ccccc3c2=O)cc1 +COc1ccc(C(=O)CC(Nc2ccc([N+](=O)[O-])cc2)C2CCCCC2)cc1 +CC(C)(C)OC(=O)NCCCCCNC1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccccc1 +CN(C)Cc1cccc(-c2[nH]c3cccc4c3c2CCNC4=O)c1 +CC(=O)N1CC(NC(=O)C=Cc2ccccc2)CC1C(=O)NO +CCc1ncc(Cc2cnc3ccc(N)cc3c2)c2cc(OC)c(OC)cc12 +Cc1ccc(-n2cnc3c(sc4cncc(N(C)C)c43)c2=O)cc1 +CN(C)c1ccc(Nc2c3cc(NC(=O)CCN4CCCC4)ccc3nc3ccc(NC(=O)CCN4CCCC4)cc23)cc1 +COc1ccc2[nH]nc(C(=O)NCC3CCN(Cc4nc(C(=O)O)cs4)CC3)c2c1 +O=C1NC(=O)C(CN2Cc3ccc(F)cc3C2=O)(c2ccc(-c3c[nH]c(=O)c(Cl)c3)cc2)N1 +CC(C)(N)CNc1nc(-c2ccncc2F)cc2cnccc12 +CCCCCCCCCCC=Cc1ccccc1C(SCCC(=O)O)SCCC(=O)O +O=C(NO)C1(S(=O)(=O)c2ccc(Oc3ccc(C(F)(F)F)cc3)cc2)CCNCC1 +CC(=O)c1ccc(Nc2ccc(Cl)cc2)c(C(=O)O)c1 +c1ccc(N2CCN(CCCNC3=Nc4ccccc4OC3)CC2)nc1 +O=C(c1ccc(NCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +CC(NC(=O)c1c(Cl)cccc1Cl)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1 +CC(C)N1CCC(CNc2ccc3ncc(-c4cccc(OC(F)(F)F)c4)n3n2)CC1 +O=C1NC(=O)N(c2ccc3[nH]cnc3c2)C1c1ccc(Cl)cc1 +CNC(=O)n1cc(NC(=O)N2C(C(=O)NC(COC)c3cccc(Cl)c3F)CC3CC32)c2ccccc21 +Cn1c(=O)c2c(nc(SCCCc3ccccc3)n2C)n(C)c1=O +COc1cc2ncnc(N3CCCC(c4ccccc4)C3)c2cc1OCCc1ccccn1 +CCCOc1ccc2[nH]c3c([N+](=O)[O-])ccc4c3c(nn4CCN(CC)CC)c2c1 +C1=C(Cc2ccc(-c3ccccc3)cc2)C2CCN1CC2 +COc1cc(C(CC=C(C)C)OC(=O)C2CCCO2)c(OC)c2c1C(=O)C=CC2=O +[O-][S+](CC1(O)CCN(CCc2c[nH]c3ccc(F)cc23)CC1)c1ccccc1 +Cn1c(-c2ccc(Cl)cc2)c(CCC(=O)N2CCC(O)(Cc3ccccc3)CC2)c2cc(-c3cccnc3)ccc21 +O=C(NO)C1(F)C(c2ccccc2)C1c1ccc(-c2ncc(Cl)cn2)cc1 +O=C(NCCCn1ccnc1)c1ccc(NCc2cc(Cl)cc(Cl)c2)nn1 +COc1cc(C2C(C#N)=C(N)Oc3c2ccc2cnccc32)cc(OC)c1OC +Cc1ccc(Cn2c(=Nc3ccc(OC(C)C)c(F)c3)[nH]c(=O)n(CCC(=O)O)c2=O)cc1 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+Cc1c(NC2CCN(Cc3ccccc3)CC2)ccc2c(=O)n(-c3cccc(Cl)c3)c3nncn3c12 +N#Cc1ccc(N2CCC(O)(c3ccc(F)cc3)C2)cc1Cl +Cc1ccc(-c2ccc(Cn3c(CC(C)(C)C(=O)O)c(SC(C)(C)C)c4cc(OCc5ccccn5)ccc43)cc2)nn1 +Cn1cnc(-c2cc3nccc(Oc4ccc(NC(=O)c5sc(-c6ccccc6)nc5-c5ccccc5)cc4F)c3s2)c1 +COCCOc1cncc(-c2nnc3c(C)nc4ccc(CN5CCOCC5)cc4n23)c1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1cnc(N2CCOCC2)nc1 +CCCNC(=O)OCC(C1CC1)n1cc(Cl)nc(Nc2cc(C)c(OC)nc2C)c1=O +N=C(N)Nc1ccc(C(=O)NCCC(=O)NC(CC(=O)O)C(=O)NC(Cc2ccccc2)C(=O)O)cc1 +NC(=O)c1cc2cc(C3CCCC3)c(C(F)(F)F)nc2nc1N +CCOc1ccc(Cc2cc(C3OC(OC)C(O)C(O)C3O)ccc2C)cc1 +CC(O)(c1ccc(C(=O)N(C2CC2)C2CCC(COC(N)=O)(c3ccccn3)CC2)cc1)C(F)(F)F +CCc1cc2c(c(CC)n1)CCC(=O)N2Cc1ccc(-c2ccccc2-c2nnn[nH]2)cc1 +CCCNC(=O)N1C(C)C(c2ccc(-c3cccc(F)c3)cc2)C1C#N +CC(NC(=O)CCc1nc2ccccc2c(=O)[nH]1)c1ccc(-n2ccnc2)cc1 +CC(C)(C)c1ccccc1N1CCN(C(=O)Cc2nnn[nH]2)CC1 +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)N(CC(=O)O)Cc3ccccc3)cc12 +O=C1NC2=NC3CCCC3N2c2nn(Cc3ccc(C(F)(F)F)cc3)c(Nc3ccccc3)c21 +Oc1cc2c(cc1Br)CCN(CC=Cc1ccccc1)CC2c1ccccc1 +O=C(Nc1ccsc1-c1ccccc1)OC12CCN(CC1)CC2 +c1ccc(-c2nc(NCCc3[nH]cc4ccccc34)c3ccccc3n2)nc1 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN1CCCCCC1 +OCC1OC(n2cnc3c(NCc4cccc(I)c4)nc(Cl)nc32)C(O)C1O +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCNC(=O)C(N)CCCCN)cc3)[nH]c2n(CCC)c1=O +COC(=O)CCCC=C(c1cc(C#N)c(OC)c(C(=O)OC)c1)c1cc(C#N)c(OC)c(C(=O)OC)c1 +Cc1ccc(NC(=O)c2ccc(C(=O)Nc3ccccc3N)nc2)cc1Nc1ncc(-c2cccnc2)s1 +CC1=C(N2CC(C)C3(CCN(CC(O)c4ccc5c(c4C)COC5=O)CC3)C2=O)COC1=O +Cc1cc2c(cc1C)C(C)(F)C(=O)N2CC1CCC(NC(=O)c2cc(Cl)cnc2C)CC1 +Cc1ccccc1N(CCO)C(=O)Nc1ccc(-c2ncnc3[nH]cc(C)c23)cc1 +COCOC(C(CNC(=O)OC(C)(C)C)c1ccc2c(c1)OCO2)C1OC(C)(C)OC1CO[Si](C)(C)C(C)(C)C +O=C(O)Cn1c(=O)c(CCc2ccc(O)cc2)nc2cccnc21 +Nc1ncc(-c2ccc(C3(c4noc(-c5cnccc5O)n4)CCC3)cn2)cn1 +CC(C(=O)OC1CC2CC(C1)N(Cc1ccccc1)C2)(c1ccccc1)c1ccccc1 +Cc1cn(-c2ccc3n(c2=O)CCN(C(C)C2CCC(c4cc(F)c(Cl)c(F)c4)O2)C3=O)cn1 +C=CCc1cc(OC)c(OC(C)C(OC2CC(C)CCC2C(C)C)c2ccc(O)c(OC)c2)c(OC)c1 +CC(C)(C)OC(=O)N1CCC(c2cc3cc(-c4ccc(S(C)(=O)=O)c(F)c4)ncc3o2)CC1 +NC(C(=O)N1CCSC1)C1CCC(NS(=O)(=O)c2ccc(F)c(F)c2F)CC1 +NS(=O)(=O)c1ccccc1N=C1C(=O)Nc2ccccc21 +NC(CSC1(c2ccc(Cl)cc2)c2ccccc2CCc2ccccc21)C(=O)O +CC(c1ccc(-c2ccn(C)c(=O)c2)cc1)N1CCC2(CCCC(O)C2)OC1=O +CNC(C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)c1nc2ccccc2s1)(c1ccccc1)c1ccccc1 +c1ccc(CN(c2ccc3[nH]ccc3c2)C2CCNC2)cc1 +O=C1CC2(CCN(C(=O)Nc3ccc(OC(F)(F)F)cc3)CC2)Oc2c(F)cccc21 +CC(=O)NC(C(=O)NO)C1CCN(c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1=O +COc1ccccc1C(=O)NCC(NS(=O)(=O)c1c(C)cc(C)cc1C)C(=O)O +C=C(C)C(=O)Nc1cc(C)cc(-c2ncnc3[nH]cc(C(=O)OCC)c23)c1 +O=C(CCC(=O)c1ccc(Oc2ccc(Cl)cc2)cc1)NO +COc1cc(-c2cn[nH]c2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 +Cc1cnc(-c2cc(Cl)ccc2F)cc1Nc1ccnc2cn(CC(N)=O)nc12 +CC(C)N1CCC(Oc2ccc(CN3CCC(O)CC3)cc2)CC1 +CC(C)C(CO)NCc1nc(-c2cccc(N3CCCC3)c2)ccc1F +Nc1nnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCS(=O)(=O)CC3)cc2F)s1 +CC(c1ccc(-c2cc(F)cc(F)c2)cc1)C(N)C(=O)N1CCC(F)C1 +Cc1ccc(C#Cc2ccc(SC(CCN3C(=O)c4ccccc4C3=O)C(=O)O)cc2)cc1 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+O=C(NCc1ccc(F)cc1)c1nc(-c2nccs2)nc(O)c1O +CCC1CCCC(C2(OC(=O)N3CC4CCC(C3)N4CCO)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCN(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(OC)cc1 +CCCc1cn(-c2nc(N)c3ncn(C4OC(COS(=O)(=O)NC(=O)c5ccccc5O)C(O)C4O)c3n2)nn1 +CNC(=O)Nc1ccc(O)cc1OCC(O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2 +Cc1c(F)cccc1NC(=O)Nc1ccc(Cl)c(S(=O)(=O)C2CCNCC2)c1O +CCCCS(=O)(=O)NCCCCC(C)C1CCC2C(=CC=C3CC(O)CC(O)C3)CCCC21C +CN(c1ncnc2[nH]ccc12)C1CC(NS(=O)(=O)NCCCC#N)C1 +CN1CCC(N2CNc3ccc(NC(=O)c4ccc(F)cc4Cl)cc32)CC1 +O=C(NC(Cc1ccccc1)C(O)CN1CCCCCCCCCCC(c2ccccc2)OC1=O)OC1COC2OCCC12 +COc1ccc(N(C(=O)c2ccccc2)C2CCN(Cc3ccccc3)CC2)cc1 +CNCCON=Cc1c(N)ncnc1Oc1ccc2[nH]c(C)cc2c1F +CCNC(=O)Nc1cc(-c2nc(C(F)(F)F)cs2)c(-c2cncc(-c3nnc(C)o3)c2)cn1 +O=C(C(=NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)C(F)(F)F)c1ccc(Cl)cc1 +Cc1cccc(-c2nc(NCc3cccc(C(N)=O)c3)sc2-c2ccc3ncnn3c2)n1 +COCC(NC(=O)c1cc(-c2ccccc2)nc2ccccc12)c1ccccc1 +CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(-c4nnc(-c5ccccc5)s4)cc32)c1C +CCCCc1nc(CO)c(Cl)n1Cc1ccc(-n2cccc2C(=O)O)cc1 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+CN(c1ccc(NS(=O)(=O)Cc2ccccc2F)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +O=C(Nc1ccccc1)Nc1ccc(C(=O)NCCN2CCOCC2)cc1 +CCC(=O)NC1CCC(CNC(=O)c2ccccc2OC)(c2ccccc2)CC1 +CNCc1cc(C#CCCN2CCOCC2)ccc1Oc1ccc(Cl)cc1 +COCCn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 +Nc1oc2ccccc2c(=O)c1C=C1COc2ccccc2C1=O +CC1c2cccc(C(N)=O)c2C(=O)N1c1ccc(N2CCOCC2)cc1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(O)cc2)nc2c(Cl)cc(Cl)cn12 +Cc1nc(NS(=O)(=O)c2ccc(-c3ccc(C#N)cc3)cc2)ccc1F +NC1CCCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(F)c(O)c(Cl)c5)nc34)cn2)C1 +O=C1NCCN1c1ccc(S(=O)(=O)Nc2cccc(Cl)c2)cc1 +CCCc1c(C(C)C)nc(C(C)C)c(C(C)O)c1-c1ccccc1O +CCc1nccc2c1c(Sc1ccc(Cl)c(Cl)c1)c1n2CCCC1CC(=O)O +COc1cc(OCc2cccc(-c3ccc(F)cn3)c2)c2cc(-c3cn4nc(C(C)F)sc4n3)oc2c1 +OCC(CO)Nc1ncnc2[nH]cc(-c3ccccc3)c12 +Cc1ccnc(N2CCN(CCCCN3C(=O)CC4(CCCC4)CC3=O)CC2)n1 +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(N)=O)cccc2-3)cc1 +CCNC(=O)c1c(-c2ccccc2)c(-c2ccc(F)cc2)c(CCC(O)CC(O)CC(=O)O)n1C(C)C +Cc1cccc(S(=O)(=O)NCCCN2CCN(c3nsc4ccccc34)CC2)c1 +OCC1CCN(c2nccnc2C2CN(c3ncc4cccc(Cl)c4n3)C2)CC1 +Cc1ccc(Oc2cnc(NC(=O)C(OC3CCOC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)cc1C(=O)O +O=C(NCC(c1ccc(C(F)(F)F)nc1)N1CCC(F)(F)CC1)c1c(F)cccc1Cl +CCC(=O)C1(C)CCC2C3CCC4=CC(=O)CCC4=C3CCC21C +COc1ccc2c(c1)C1(CC1c1ccc3c(C=Cc4ccc(CN5C(C)CN(C)CC5C)cc4)n[nH]c3c1)C(=O)N2 +CN(C(=O)c1ccc(C#Cc2cccc(Cl)c2)cn1)C(C)(C)C +O=C(NO)C(CO)OC(CO)c1ccc(C#CC#Cc2ccccc2)cc1 +CC(C)C1(C(=O)N2CCc3ccc(C(F)(F)F)cc3C2)CCC(NC2CCc3c(C#N)cccc32)C1 +Cc1ccc(S(=O)(=O)n2c(CCCN3C(=O)c4ccccc4C3=O)nc3cc(Cl)c(Cl)cc32)cc1 +N#Cc1ccccc1N1CCN(CCCCN2C(=O)C3CCCN3C2=O)CC1 +COc1c(C)c2c(c(O)c1CC=C(C)C=CP(=O)(O)O)C(=O)OC2 +Cc1c(CN2CCc3c(c(=O)n(CCN(C)CCc4ccccn4)c(=O)n3CC3CCCCC3)C2)sc2ccccc12 +N#Cc1ccc2cc1Oc1ccc(C#Cc3ccccc3)c(c1)CN1CCN(CC1=O)Cc1cncn1C2 +O=[N+]([O-])c1ccc(N2CCNCC2)cc1NCc1ccc(Cl)cc1 +Cc1nc(-c2cnn(C)c2-c2ncc(C(F)(F)F)cc2F)c2c(N3CCC3)ncnn12 +COc1cccc(-c2ccc(OCc3cc(C(=O)O)oc3C)cc2)c1 +O=C(O)c1cc(-c2cccc(O)c2)nc2c1cnn2Cc1ccncc1 +NS(=O)(=O)CC(CC(=O)Nc1ccc(Oc2ccc(Cl)c(Cl)c2)cc1)c1ccccc1 +O=C(CCl)Nc1cc(-c2ccccc2)c(-c2nnc3sc(-c4cccc([N+](=O)[O-])c4)nn23)s1 +COCCNC(=O)c1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 +CN(C(=O)C1CCCN1C(=O)C(NC(=O)C=Cc1ccc(OP(=O)(O)O)cc1)C(C)(C)C)c1ccccc1 +CN1CCN(c2cccc(Nc3nc4c(-c5ccc(N(C)S(C)(=O)=O)cc5)cccn4n3)c2)CC1 +CC(C)Oc1nc(-c2ccccc2OC(F)(F)F)cc2nc(-c3c(Cl)c(C(C)(C)C)nn3C)[nH]c12 +Cc1cc(C(=O)Nc2cc(C(F)(F)F)ccn2)ccc1-c1nc(C2CCC3CCC(=O)N3C2)n2ccnc(N)c12 +CN(C)CCCn1nc(C2=C(c3cn(-c4cccs4)c4ccccc34)C(=O)NC2=O)c2ccccc21 +CNCc1cc(Br)cc(OCc2ccc3ccc(N)nc3c2)c1 +C=CCN(CCC)Cc1c(C)nc2n(-c3c(C)cc(C)cc3C)c3ncccc3n12 +CC(Oc1cc(-c2cnn(C(F)F)c2)cc2ncsc12)C1CNC(=O)O1 +CC1(C)Oc2ccc(C#N)cc2C(n2ccccc2=O)C1O +CN1C(CC(=O)c2ccccc2)CCCC1CC(OS(=O)(=O)c1ccccc1)c1ccccc1 +COc1cc(-c2ccc(Cl)cc2C)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 +N=C(N)c1cccc(-n2nc(C(F)(F)F)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2F)c1 +CC1(C)c2cc(C(=O)NCCNS(N)(=O)=O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +O=C(c1cccnc1)C(F)(F)CCCCOc1cccc(OCc2ccccc2)c1 +O=C(Nc1cc2ccc(Oc3ccccc3)cc2cn1)C1CC1 +Cc1ccccc1C1CC2CCC(C1)N2C(=O)C(CCCc1ccccc1)NC(=O)C(C)(C)N +CCOc1nc(-c2cc(OCC3CC3)cc(OCC3CC3)c2)c2cc(OC)c(OCCO)cc2n1 +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)cn(C)c2=O)C3=O)c(OC)n1 +CC(C)(C)NCC(O)c1ccc2c(c1)C[OH+][BH](O)(O)O2 +CCCOc1c(OCCCO)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1S(=O)(=O)CC(C)=O +COc1ccc(-c2cc3c(nn2)c(NCC(=O)N(C)C)nc(=O)n3CCOCC(F)(F)F)cn1 +COc1ccc(C2CCCCC2NC(=O)C(c2ccccc2)c2ccccc2)cc1 +Cc1cccc(O)c1C(=O)N1CCC(C)(N2CCN(C(C)c3ccc(C(F)(F)F)cc3)C(C)C2)CC1 +Cc1ccccc1N1CCN(c2ccc(S(=O)(=O)C3(C(=O)NO)CCOCC3)cc2)CC1 +O=c1[nH]c(=O)n(C2CC(O)C3(CO)CC23)cc1I +Cc1nc(C(C)(C)NC(=O)c2ccc(C3CC3)c(OCC3CCOCC3)n2)no1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2cnn3ccccc23)CC1 +Cn1nc(Cl)c2cn3nc(NCCN4CCN(c5ccccc5Cl)CC4)ccc3c2c1=O +CC12CC(=O)C3C(CCC4CC(O)CCC43C)C1CC(=N)N2 +CC(C)(Cn1c(=O)[nH]c(=Nc2cccc(OC(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O)C(=O)O +Cc1ccc(C(=O)Nc2cccc3c(=O)cc(C(=O)O)oc23)cc1 +Cc1ccc(N2C(=O)C(=CNc3ccccc3-c3nnc(S)nc3O)c3ccccc3C2=O)cc1C +CCN(CCCCCC(=O)c1ccc(N2CCCC2)cc1)Cc1ccccc1OC +CNc1nc(Nc2cnn(CCC#N)c2C)ncc1C(F)(F)F +O=C(Nc1ccc(CCC2CCCNC2)cc1)c1ccc(Cl)cc1 +CNCC(O)CCN1c2ccccc2N(c2cc(F)ccc2F)S1(=O)=O +COc1cc(OC)cc(N(Cc2ccc(Cl)s2)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1 +CC1(NC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(Cl)cc3Cl)n(-c3ccccc3)n2)COC1 +Cc1cccc(Cc2n[nH]c3cc(O)c(C(=O)N(C)Cc4ccccc4Br)cc23)c1 +CC(=O)c1nc(CC(=O)N2C(C(=O)NC(CO)c3cccc(Cl)c3F)CC3CC32)n2ccccc12 +CC(NC(=O)c1ccno1)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 +CSc1nc(NC(=O)Cc2ccccc2)n2nc(-c3ccco3)nc2n1 +Cc1ccc(CN2CCC(N3Cc4cccc(C(N)=O)c4C3=O)CC2)cc1C +Cc1csc2nc(C(C)NC(=O)C=Cc3ccc(Br)o3)oc(=O)c12 +CC(C)CC(NC(=O)C(NC(=O)COc1ccc2c(c1)Nc1ccccc1S2)C(C)O)C(=O)NC1CCOC1O +O=C(NC1CCOCC1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CCOC(=O)COc1ccc(Oc2cc(-n3nc(C)n(C(F)F)c3=O)c(F)cc2Cl)cc1 +N#Cc1ccc(-c2nc(NCCNc3ccc([N+](=O)[O-])cn3)ncc2C(=O)NCCN)cc1 +COc1cccc2c(O)nc(-c3ccc(C(F)(F)F)cc3)nc12 +COC(=O)C1C(C=Nc2cncnc2N)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2cc(O)ccc2n1Cc1ccccc1 +Cn1c(=NC=Cc2sc3ccc(Cl)cc3[n+]2C)sc2ccccc21 +CC12CCCN(C(=O)c3ccc4nc[nH]c4c3)C1CCc1ccccc12 +CCN(CC)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3CC(c2ccccc2)c2ccccc2)cc1 +COc1cc2ccccc2cc1C=C1SC(=S)N(CC(=O)O)C1=O +O=C1c2cccc3c([N+](=O)[O-])ccc(c23)C(=O)N1C1CN2CCC1CC2 +CCC(=O)N(c1ccccc1)C1(COC(=O)C(C)(C)C)CCN(CCc2cccs2)CC1 +CCOC(Cc1ccc(OCCN2CC=C(c3ccc(OC)cc3)CC2)cc1)C(=O)O +CCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2C(F)F)CCC3)cc1 +Nc1ccc2c(c1)-c1c(cccc1C(=O)NCCCCN1CCN(c3cccc(Cl)c3Cl)CC1)C2 +COc1ccc(C=Cc2cc3c(c(=O)n(C)c(=O)n3C)n2C)cc1 +O=C(c1ccccc1)n1cc(C=Nc2ccc(C(F)(F)F)cc2)c2ccccc21 +CCCCCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)nn1 +O=C(Nc1ccc2c(c1)OCCO2)c1cc2sccc2n1Cc1ccc(F)cc1 +N#Cc1ncc(F)c(N(CCc2cccc(Br)c2)Cc2ccc3c(c2)OCO3)n1 +CC(=O)c1c(C)nc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1NC1CCC(CN(C)C)CC1 +O=C(C1CSC(c2cccnc2)N1)N1CCN(CCCc2ccccc2)CC1 +CCc1ccc2[nH]nc(C(=O)NCC3CCN(CC(=O)O)CC3)c2c1 +N=C(N)c1cccc(Oc2cc(Br)ccc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +COC(=O)c1ccc(C)c(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)c1 +COc1ccc(C(O)(c2cncnc2)c2ccccc2Cl)cc1 +CCC1C(=O)N(C2CCN(CCCc3ccccc3)CC2)c2ccccc21 +Cc1ccc(N2C(=O)C3C(c4ccccc4)NC4(C(=O)c5ccccc5C4=O)C3C2=O)cc1Cl +O=C(CCCCc1cccs1)Nc1ccc2c(c1)COC(C(=O)O)C2 +CCOC(=O)C1=C(CN2CC(F)(F)CC2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Br +CCCCCCNC(=O)CN1CC(=O)N(C)C(Cc2ccc(-c3cc(OC)c(OC)c(OC)c3)cc2)C1=O +Cc1c2c(cc[n+]1Cc1ccc(F)cc1)c1ccc(OCc3ccccc3)cc1n2Cc1ccccc1 +CN1CCC(n2cc(S(=O)(=O)c3ccccc3)c3cccnc32)C1 +O=C(OC1CC2CCC(C1)N2CCc1ccccc1)c1ccccc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCNC(C)=O)cc3)[nH]c2n(CCC)c1=O +CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CCN(C(C)(C)C(N)=O)CC3)n(C)c2n1 +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)nc2c(F)cccn12 +CCn1cncc1C(OC)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cc3ccccc3)c1)cc(=O)n2C +CN1CCN(Cc2ccc3c(c2)Cc2c(-c4csc(C#CCNC(=O)Oc5ccccc5)c4)n[nH]c2-3)CC1 +CC(C)CC(NC(=O)c1cc(COc2ccccc2)ccc1CCC(=O)O)c1ccccc1F 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+CN1CCc2ccc(NS(=O)(=O)c3ccc(-c4ccc(C#N)cc4)cc3)cc2CC1 +Cc1ccc2oc(C=Cc3ccc(N(C)C)cc3)cc2c1 +O=C(NCC(O)CN1CCc2ccccc2C1)c1cncc(NC2CCOCC2)c1 +NN(C(=O)c1ccc(Cl)cc1Cl)S(=O)(=O)c1ccc2ccccc2c1 +O=C(NCc1ccc(NS(=O)(=O)C2CCCC2)cc1)c1cc2cnccc2[nH]1 +NC1=NC2(c3ccccc3)CN(c3ncc(F)cn3)CC2CS1 +COc1ccc(OC)c(S(=O)(=O)n2cc(CCN(C)C)c3cccc(OC)c32)c1 +Clc1ccc(Nc2nccc(N3CCN(c4ccnc5cc(Cl)ccc45)CC3)n2)cc1 +CCN(C)C(=N)c1ccc(C(=O)N2CCN(S(=O)(=O)c3cc4ccc(Cl)cc4s3)CC2)cc1 +Nc1nc2ccccc2n2c(=O)n(-c3ccc(Cl)cc3)nc12 +CCOc1ccc(OC)c(C2CC2NC(=O)Nc2ccc(Br)cn2)c1F +Cc1cc(F)cc(-c2[nH]c(CNc3ccccc3)nc2-c2ccc3ncnn3c2)n1 +O=C(N1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)C(O)C1)C1(C(F)(F)F)CC1 +O=C(CC(c1ccccc1)c1ccccc1)N1CCN(Cc2cccnc2)CC1 +O=C(O)C1CN(Cc2ccc(-c3nc4cc(Cc5ccc(Cl)cc5)ccc4s3)c(F)c2)C1 +CC1CC(=O)Nc2cccc(C(=O)Nc3cccc(-c4cnco4)c3)c2N1 +CCCN(CC1CC1)C(=O)c1c(CC)nc2n1CCN2c1c(C)cc(C)cc1C +O=C(COc1ccc(-c2ccccc2)cc1)Cn1nnc2ccccc21 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC(C)(Cc1ccccc1)C(=O)NCCCCCCCNC(N)=O +OC(c1ccc(C(F)(F)F)cc1)(c1cccnc1)c1ccc(Cl)cc1F +COc1cc(F)cc2c1nnc1c(C)nc(-c3cccnc3C)n12 +Cn1cncc1C#Cc1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O +CC(C)C(NC(=O)CCN(C)C)c1cccc(F)c1N1CCN(C(=O)C2CN(C(C)C)CC2c2cccc(Cl)c2)CC1 +O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ncccn3)cc2)c2ccccc12 +COC(c1ccc(C(F)(F)F)cc1)C1CC1c1cc(C)c(OC(C)(C)C(=O)O)c(C)c1 +N#CC(=CC1CC1)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cccc(F)c3)cc2)c2c(N)ncnc21 +COC(=O)C(C)NP(=O)(OCC1OC(n2cc(F)c(=O)[nH]c2=O)CC1O)Oc1ccccc1 +CC(=O)NC1C(O)C=C(C(=O)O)OC1C(O)C(O)Cn1cc(CO)nn1 +N#Cc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)NC(CCO)c3ccccc3)cc1)C2 +CCOC(=O)CCS(=O)(=O)c1nc(-c2ccccc2)cc(C(F)(F)F)n1 +O=C1CN(c2cccc(-c3n[nH]c(C4CCCCN4C(=O)COc4ccccc4)n3)c2)C(=O)N1 +CCC1(C(=O)Nc2cc(CN3CCOCC3)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)C1C +COC(=O)CC1c2ccccc2N=C(NCCCCCN)N1c1ccc(-c2ccccc2)cc1 +CN1C2CCCC1CC(NC(=O)c1cccc3oc(N4CCOCC4)nc13)C2 +CC(=O)OCC1=C(C(=O)O)N2C(=O)C(NC(=O)Cn3nc(C(F)F)c(Cl)c3C)C2SC1 +COc1ccc(C(=O)C(Cc2ccccc2)=C(C(=O)O)c2cc(OC)cc(OC)c2)cc1 +COC(=O)C(=O)OC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +CC1(C)c2cc(Oc3ncccn3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +O=C(NCCO)C1=Cc2c(ncnc2Nc2ccc(Oc3cccc4sccc34)c(Cl)c2)NCC1 +COc1c(C(=N)N)cccc1-c1cc(-c2ccc(C(=N)N)cc2[N+](=O)[O-])no1 +CCC(=O)NC1CC(n2cnc3c(NCC(c4ccccc4)c4ccccc4)nc(NCCc4cn(CC)cn4)nc32)C(O)C1O +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCCc1scnc1C)CC2 +CC(C)C#CC1(C(F)(F)F)NC(=O)Nc2ccc(F)c(F)c21 +COc1ccc(C2CC(c3ccccc3)=NN2C(N)=O)cc1 +O=C(Nc1nc2c(s1)COc1ccccc1-2)c1ccc(Nc2ccncn2)cc1 +O=C1CC(O)CC(C=Cc2c(Cl)cc(Cl)cc2OCc2ccc(F)cc2F)O1 +NC(=O)c1cc(-c2ccc(OCCN3CCCOCC3)c(Cl)c2)nc2c1[nH]c1cc(N3CCOCC3)ccc12 +O=C(NCCCCCCCNc1c2c(nc3ccccc13)CCCC2)c1cc2cc(OC(F)(F)F)ccc2oc1=O +CNC(=O)c1c(C(N)=O)nc2n1CCOc1cc(F)c(C#CC(C)(O)c3ccccn3)cc1-2 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC(C)N(S(C)(=O)=O)CC3)cc12 +CN(C)c1ccc(C(=O)N2CCCN(C(=O)Nc3ccc(C(C)(C)C)cc3)CC2)cc1 +O=C1OC2(CCC(N3CCC(Cc4ccccc4Br)CC3)CC2)c2ccc3c(c21)OCCO3 +COc1ccc(-c2ccc(C(=O)N3CCc4cc(OC)c(OC)cc4C3)o2)cc1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1C2CCC1c1nnc(-c3ccc[nH]3)n1C2 +CCCC(C(N)=O)C(CC(C)C)C(=O)NC1CCCCN(Cc2cccc(-c3ccc(F)c(Cl)c3)c2)C1=O +COc1ccc(-c2c(-c3cc(Cl)c(O)cc3O)noc2NC(=O)C(C)(C)C)cc1 +N#CCc1cc(-c2ccc(Cl)cc2)n(-c2ccc(S(N)(=O)=O)cc2)n1 +CCC(C)C(NC(=O)C(S)Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)O +COc1cc(Cl)ccc1-c1ccnc2[nH]c(C3CNC(C)(C)CO3)cc12 +COc1ccc(Cc2cc(C3CCN(C(=O)c4ccc5c(c4)OCO5)CC3)ncn2)cc1 +COC(C)(C)c1cnc2n1CC(c1cccc(F)c1F)CCC2NC(=O)N1CCC2(CC1)OC(=O)Nc1ncccc12 +Cc1cc(C)c(S(=O)(=O)NC(C)COc2cccc3c2cnn3-c2ccc(F)cc2)c(C)c1 +Cc1ccc(-c2ccc(S(=O)(=O)C(CCN3C(=O)c4ccccc4C3=O)C(=O)O)cc2)cc1 +c1ccc(-c2nc(OCCCN3CCCC3)cc(C3CC3)n2)cc1 +COCCN(C)S(=O)(=O)c1ccc(Nc2nccc(-c3cnc(C)n3C3CC3)n2)cc1 +CC1(F)OC(n2cc(F)c(=O)[nH]c2=O)C(O)C1O +COC1CCC2(C=C(c3cc(-c4ccc(Cl)cc4)ccc3C)C(=O)N2)CC1 +CC1CCC(COc2ccc(F)cn2)CN1C(=O)c1cccc2cc[nH]c12 +CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)c1cnccn1)B(O)O +CC(O)C(NC(=O)N1CCC(c2ccc(-c3ccccc3)cc2)CC1)C(=O)NO +Cc1ccc2[nH]nc(C)c2c1-c1nc2c(c(N3CCC4OCC4(C)C3)n1)CN(c1c(Cl)c(C3CC3)nn1C)CC2 +Cc1cn(-c2ccc(C(N)=O)c(NC(C)(C)C)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c12 +COc1cc2cc(CO)c(CO)c(-c3ccnc(-n4c(=O)ccc5ccccc54)c3)c2cc1OC +CC(CC(=O)O)NC(=O)N1CCC2(CC1)CCN(c1ccc(C(=N)N)cc1)C2=O +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cc(C(C)C)co1 +CCOP1(=O)N=C(C2=C(O)C(C(C)(C)C)N(CCC(C)(C)C)C2=O)Nc2ccccc21 +NS(=O)(=O)c1ccccc1NC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4c[nH]c(=O)cn4)ccn23)c1 +Cc1cc(OCc2c(-c3ccc(Cl)cc3)noc2C(F)(F)F)c(F)cc1CCC(=O)O +Cc1c(-c2nnnn2C2CCCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Br)cc1 +COCc1ccccc1C1C(C(=O)c2cccnc2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +Cc1nc2nc(C(=O)NCc3ccco3)cn2c(-c2ccc(Cl)cc2Cl)c1CN +COC(=O)c1cnc(N2CCN(c3nnc(C(=O)c4ccccc4)c(C)c3C)CC2C)cn1 +O=C(NC1C2CN(Cc3cccs3)CC21)C(O)(c1ccccc1)C1CCCC1 +CN1CCN(CC(=O)OC2CC3(N4CCCCC4)CC(c4ccccc4)C2C(c2ccccc2)C3)CC1 +CC(=O)N1CCN(c2ccc(Cl)c(C3CC(=O)C(Sc4ccccc4Cl)=C(O)C3)c2Cl)CC1 +COCC(C)Oc1nc(Nc2ccc(S(C)(=O)=O)cc2)ncc1C(F)(F)F +O=C(NCc1ccc(-c2cc[nH]c(=O)c2)cc1)c1cccc(F)c1Cl +OCC(O)COc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +N#Cc1ccccc1-c1cc(-c2ccsc2)cn(-c2ccccc2)c1=O +COc1ccc(C2=NN(C(N)=S)C(c3cccc4ccccc34)C2)cc1 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2o1 +O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2ccccc2O)CC1 +O=C(c1ccco1)N1CCCCC1c1nnn(-c2cccc(Cl)c2)n1 +N=C(N)c1cccc(Oc2ccc(Cl)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +CC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCCC2C(O)c1ccc(Oc2ccccc2)cc1 +COc1cc(OC)nc(OC(C(=O)O)C(OC)(c2ccc(Cl)cc2)c2ccc(Cl)cc2)n1 +O=C1C=CC2(CC(c3coc([N+](=O)[O-])c3)OC(c3coc([N+](=O)[O-])c3)O2)O1 +COc1cc(F)ccc1-c1nncc2cc(S(=O)(=O)Nc3nccs3)ccc12 +CCCCN1c2cccc(Cl)c2CN(CC(=O)NO)S1(=O)=O +Fc1cccc(F)c1Cn1ccc2c(OC3CCN(Cc4cscn4)CC3)ncnc21 +COCC(C1CC1)n1cc(Cl)nc(Nc2cc(C)c(OCF)cc2C)c1=O +CC(C)(NC(=O)c1cc2c(NC(=O)c3ccc(CN4CCCCC4)cc3)n[nH]c2s1)c1ccccc1 +NS(=O)(=O)OCC1CC(Nc2ncnc3[nH]c(-c4cccc5ccccc45)nc23)CC1O +Cc1ccc2c(c1)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C(F)(F)F)nc1N2 +COc1ccc(C(=O)Nc2ncc(-c3ccc(C(=O)O)cc3OCc3ccccc3C#N)s2)cc1 +COc1cc2ccccc2nc1COc1ccc(-c2nn(C)cc2-c2ccncc2)cc1 +Cc1n[nH]cc1C(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)C1 +Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(C)(=O)=O)C3)c1-c1ccc(F)cc1 +CC1CN(C)CCC1c1cc2c(cc1-c1cccc(F)c1)OCC1=NNC(=O)C(C)N12 +Cc1ccccc1C1CCc2cc(Oc3ncc(C(=O)NCc4ccnc(Cl)c4)s3)ccc2O1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=NC#N)SC2CCCC2)CC1 +CCCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +COc1cc(NC(=O)C2CC2)c(Cl)cc1C(=O)NC1CCN(Cc2ccccc2)C1 +OCC1OC(n2cnc3c(NC4CCCCC4)ncnc32)C(O)C1O +CC(C)CC(NC(=O)C1CCCC1C(=O)c1ccc(CNc2nccs2)cc1)C(=O)NC1CCCCC1c1ccccc1 +CC(=O)c1ccc(-c2ccc(C(=O)C(F)(F)F)s2)cc1 +O=c1oc2ccccc2n1CCCCCCN1CCN(c2ccccc2)CC1 +C#CCN1CCc2c(C)c3c(n2-c2cc(Cl)c(C(N)=O)cc21)CC(C)(C)CC3=O +O=C(OC1C[N+]2(Cc3nc4ccccc4o3)CCC1CC2)C1(C2=CC=CC2)CCCCCC1 +COc1ccc(NC(C)=O)cc1C1CN(c2nc(-c3ccncc3F)cc(=O)n2C)CCO1 +Cn1c(=O)n(-c2cccc(C(F)(F)F)c2)c2c3cc(-c4ccc(S(C)(=O)=O)cc4)ccc3ncc21 +Cc1ccc2c(c1)C1(NC(=O)NC1=O)N(C)C(=O)N2 +COCC(C1CC1)n1cc(Cl)nc(Nc2c(C)nc(OC)nc2OC)c1=O +O=C(Nc1ccc(F)cc1F)c1cc2nc3c(c(C(F)(F)F)n2n1)CCCC3 +CC(O)(c1ccccc1)c1ccnc(Nc2ccc(C#N)cc2)n1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)Cc1ccccn1)C2 +C#Cc1ccc2nc(-n3ccnc3)nc(NCc3ccccc3)c2c1 +CC(=O)Nc1cccc(-c2cc(N3CC(N)C(c4cc(F)c(F)cc4F)C3)ncn2)c1 +CN(CCCCN1C(=O)COc2ccccc21)Cc1ccc(Cl)cc1 +Cc1cncn1CCCNC(=C[N+](=O)[O-])NC1CCCCC1 +S=c1oc(-c2ccc3ccccc3n2)nn1CNc1ccc(Cl)cc1 +CC(C)S(=O)(=O)c1cc(-c2ccc(CCNCC(O)c3ccccc3)cc2)ccc1C(=O)O +O=Cc1ccccc1OCc1cn(Cc2ccc3c(c2)C(=O)c2ccccc2C3=O)nn1 +CC(C)(O)Cc1cn2c(N3CCN(C(=O)CCS(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)cccc2n1 +Cc1ccc(OCc2ccc3c(c2)CCN(C2CCOCC2)C3)c(-c2csc(N3CC4CC4(C(=O)O)C3C)n2)c1 +CCOP(=O)(CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)OCC +CC(NC(=O)CC(N)=O)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 +Oc1nc(NCCCNCc2cc(Br)cc(Br)c2)nc2ccccc12 +CN(Cc1c(C(=O)NC2CCCC(O)C2)noc1-c1ccc(C(F)(F)F)cc1)C1CCOC1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1nc2cc(N3CCCC3)ncc2[nH]1 +CCCCCCCN(CC)CCCCc1ccc([N+](=O)[O-])cc1 +COC12C(=O)CCC1(CO)C2C1(C)OC1CC=C(C)C +Cc1onc(-c2ccccn2)c1COc1ccc(C(=O)NC(C)C)cn1 +CCOc1c(Br)cc(Cl)cc1CNCCCNc1nc2ccccc2[nH]1 +Cc1ccc(-c2nnc(-c3ccc(C(=O)C(F)(F)F)s3)o2)cc1 +Cc1nc(N)ccc1CNC(=O)Cn1c(C)cc2c(c1=O)NC(=O)CC2 +O=C(CCCCCNC(=O)NC(=O)c1c(Cl)cccc1Cl)NO +CC(=O)Nc1cc(-c2nnc(SCc3cccc(C#N)c3)o2)ccn1 +CC(C)CN(Cc1ccc(N2CCN(C(=O)CC#N)CC2)cc1)S(=O)(=O)Cc1ccccc1 +COc1c(OCCCCN2CCNCC2)cc(O)c2c(=O)cc(-c3ccccc3)oc12 +Fc1ccc(-n2c3c(c4cc(F)ccc42)CN(CCc2cnccn2)CC3)cc1 +O=C(c1cccc(Cl)c1)N1CCC(CNCc2cccc(-n3cccn3)n2)CC1 +Cc1cc(S(=O)(=O)N2CCC(F)(F)CC2)cnc1-c1ccc2c(c1)CCC(C)N2C(=O)c1ccc(O)cc1O +O=C1N=C(O)SC1=Cc1ccc(OCCc2ccccn2)cc1 +Nc1cc(C(F)(F)F)c(-c2cc(Nc3cnc4ccccc4c3)nc(N3CCOCC3)n2)cn1 +O=C(NCCNc1ccnc2cc(Cl)ccc12)Nc1ccc(Cl)cc1 +O=S(=O)(Nc1cscn1)c1cc(Cl)c(OCC2NCCC=C2c2ccc(F)c(F)c2)cc1F +O=c1[nH]c(=O)n(COC(CO)CO)cc1Cc1cccc(Oc2ccc(F)cc2)c1 +CC1CN2c3c(cc4c(N5C(=O)OCC5CCCO)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1ncc(C(C)CC(C)(C)C)s1 +Cc1c(C(O)CN2CCC3(CC2)CCN(c2cn(C)c(=O)cn2)C3=O)ccc2c1COC2=O +CCN(CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1)C(=O)c1ccc2nc(N(C)CC)oc2c1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCN3CCCCC3)c3ccccc23)cc1 +CC1(C)C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4cc(Cl)ccc34)nnc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(Cc2cccnc2)CC1 +Cc1nc(-c2ccc(Cl)cc2)sc1C=CC1CCCN(c2cccc(C(=O)O)c2)C1 +CC(CN(C)C)NC(=O)c1c(F)cc(-c2noc(C(F)(F)F)n2)cc1F +CC(CCc1ccc(-c2cccc(C(N)=O)c2)cc1)(C(=O)NO)S(C)(=O)=O +CNCC(O)C(c1cccc(F)c1)N1CC(C)(C)c2cccc(F)c21 +OCCOCCn1cnc2nc(NCc3ccc(Cl)c(Cl)c3)nc(O)c21 +CN(C)CCn1cc(-c2ccncc2)cc(NC(=O)C(Cc2ccccc2)NC2(c3ccccn3)CC2)c1=O +CCCc1cc2c(=O)c(-c3ccc4c(c3)OCCO4)coc2cc1OS(C)(=O)=O +CC(NCc1cc2ccccc2[nH]1)c1ccc(F)c2ccccc12 +CCC(COc1ccc(C(F)(F)F)cc1)CSc1ccc(OCC(=O)O)c(C)c1 +CC(=O)Cn1nc(CNC2CCC(F)C2)c(C)c1-c1cc(F)cc(F)c1 +CCC12CCC(=O)C=C1c1c(cc(OCC(=O)OC)c(Cl)c1Cl)C2 +CC(Nc1cc(-c2sc(C3(O)CCN(C)CC3)nc2-c2ccc(F)cc2)ccn1)c1ccccc1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(C(C)CN(C)CCc3ccccn3)c2=O)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC(C)(C)O)c3)C2)cc1 +COc1cc(CC(=O)O)cc(OC)c1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +CC(c1cccc(O)c1)n1cnc2c(N(C)C)ncnc21 +CCCC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3cccc(C)c3)c3ccccc23)CC1 +OCC1OC(c2cc(Cc3ccc(OC4CCOC4)cc3)c(Cl)s2)C(O)C(O)C1O +COc1cc(NC(=O)NOCCCCCC(=O)NO)c2ncccc2c1 +CCOC(=O)c1cc2c(n1CC)C(=O)C(Oc1ccc(Cl)cc1)=CC2=O +CCC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1NC1CCC(CN(C)C)CC1 +CC1(C)c2cc(-c3nc4c(C(N)=O)cccc4[nH]3)sc2C(C)(C)N1O +COC(=O)C12OCC34C(CC5C(C)C(=O)C(O)CC5(C)C3C(O)C1O)OC(=O)C(OC(=O)C=C(C)C)C24 +O=C(C=CCNC12CC3CC(CC(C3)C1)C2)N1CCc2c(sc3ncnc(Nc4ccc(Cl)c(Cl)c4)c23)C1 +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)cc1)Nc1cc(C(F)(F)F)ccc1Cl +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3)cc2n(C)c1=O +O=C(Cc1ccc(Cl)c(Cl)c1)Nc1nc2ccc(OC(F)(F)F)cc2s1 +CNc1nc(Nc2ccc(-c3cn(C)nc3C)cc2OC)ncc1C(F)(F)F +Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCN(C)CC4)c(F)c3)cc12 +CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(CN3CCOCC3)n1CCO2)CF +CC(C)n1cnc2c(Nc3cncnc3)nc(C(C)(C)CO)nc21 +CC1(C)C=C(c2ccccc2)Nc2c(C(=O)NC34CC5CC(CC(C5)C3)C4)cnn21 +CC(C)Oc1ccccc1N1CCN(CCCCn2ncc(N3CCN(CC4COc5ccccc5O4)CC3)c(Cl)c2=O)CC1 +CCS(=O)(=O)NC(=O)c1c(-c2ccc[nH]c2=O)c2c3occc3ccc2n1Cc1cc(F)ccc1F +NC(Cc1ccccc1)C(=O)NC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +NS(=O)(=O)c1ccc(COC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)cc1 +CC1CN(Cc2ccc(N(C)C(=O)c3ccc(Oc4cccc(F)c4)cn3)cc2)CCN1 +NC1=NC(c2ccccc2)N(c2ccc(Cl)cc2)C(N)=N1 +CC(C)(CN1CCCC1)n1cnc(NC(=O)C(NC(=O)Cc2cc(F)cc(F)c2)c2ccccc2)c1 +O=C(C=Cc1ccc(Sc2cccc(OC3CCSCC3)c2)c(C(F)(F)F)c1C(F)(F)F)N1CCOCC1 +CCCN(CCC)c1c(CC)c(Nc2ccc(OC)cc2Cl)nc2ccnn12 +CS(=O)(=O)Nc1ccc(Nc2ccc3[nH]nc(N)c3c2)cc1 +CC(C)CC(NC(=O)C(CS)C(C)c1ccccc1)C(=O)O +CCn1nccc1NC(=O)c1ccc(C)c(Nc2nc(N)nc(NC(C)C)c2C#N)c1 +COc1cc(C#CCN(C)C)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2C(=O)N(C)C3)n1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccc(OCCC(F)(F)F)cc2)c1 +Cc1cc(Nc2n[nH]c3ncc(F)cc23)nc(C2CCCCCC2)n1 +C[N+](C)(C)CC1COC(C(c2ccccc2)c2ccccc2)O1 +O=C(C=Cc1cccc2c1N(Cc1ccc3ccccc3c1)C(=O)C2(CO)CO)NS(=O)(=O)c1ccc(F)c(F)c1 +CC(NC(=O)C(CS)C(C)c1ccc2c(c1)OCO2)C(=O)O +NS(=O)(=O)c1ccc(NC(S)=NCCC(=O)O)cc1 +COc1cc(N2CCN(C(=O)Cn3nc(CN)c(Cl)c3C)CC2)ccc1Cl +COc1cc(C(N)=O)c2ncnc(NCc3cccc(C(F)(F)F)c3)c2c1 +COc1cc(OC)cc(C(=O)NCc2n[nH]c(=S)n2-c2cccc(C(F)(F)F)c2)c1 +Cc1nnc2c(NC(C)C)nc(-c3nc4cnc(N5CCOCC5)cc4n3Cc3ccc(F)cn3)cn12 +Clc1ccc(Cn2cc(-c3ccc4[nH]ncc4c3)nn2)cc1 +Cc1ccc(C(c2ccccc2Cl)N2C3CCC2CC(O)(c2cccc(F)c2)C3)c(Cl)c1 +CCCCC(=O)Oc1cccc2c1-c1cc(OC)cc3c1C(C2)N(C)CC3 +COc1ccc(-c2cccc(-c3c(C)cnc4c(C(F)(F)F)cccc34)c2)cc1S(C)(=O)=O +CCCn1c(=O)c2nc(-c3cnn(Cc4cc(-c5ccccc5Cl)on4)c3)[nH]c2n(CCC)c1=O +CCS(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CCCN1CCN(C(C)=O)CC1)CCCC3)C(=O)N2 +CC(CNc1ccc(-c2ocnc2C(=O)O)cc1)NCC(O)c1cccc(Cl)c1 +CSc1nc(Nc2ccccc2)c2cnn(CC(C)c3ccccc3)c2n1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3cccc(C4CCN(CC(=O)N(C)C)CC4)c3)nc12 +CC1CCCN1C1CCC(c2ccc(NC(=O)c3ccc(F)cc3)cc2)C1 +Nc1ncnc2c1nc(Sc1cc3ccoc3cc1Br)n2CCC1CCN(C=O)CC1 +O=C(Nc1ccccc1)N1CCN(Cc2ccc(Cl)c(Cl)c2)CC1 +O=C(NCc1cccc(Cn2cccc2C(=O)O)c1)NC12CC3CC(CC(C3)C1)C2 +O=C(O)CCCN1CC(C(=O)O)Oc2c(NC(=O)c3ccc(OCCCc4ccccc4)cc3)cccc21 +CC(C)(C)c1ncc(Cc2cn(CC(=O)N3CCN(c4ccc(Cl)cc4)CC3)c(SCc3ccc(F)cc3)nc2=O)cn1 +Cc1ccc(S(=O)(=O)c2nnn3c2nc(NC2CCCCC2)c2sccc23)cc1C +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3cc(Cl)c(OC(F)F)cc3C)ncnc21 +NS(=O)(=O)c1cc2c(s1)S(=O)(=O)C(CCN1CCOCC1)CN2 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCOCCOC(=O)CC(=O)OCC +O=C(CN1CC(CNS(=O)(=O)c2ccccc2)=CCC(NC(=O)c2ccc3ccccc3c2)C1=O)NC1CC(=O)OC1O +CCCCc1nnc(SCC2CCCCC2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +CCn1c(=O)c2nc(-c3ccc(Cl)cc3N)[nH]c2n(CC)c1=O +CCC(C)N1C(=O)C(NC(=O)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)N=C(C2CC2)c2ccccc21 +CCCn1c(=O)c2nc(C3CCC(=O)C3)[nH]c2n(CCC)c1=O +Fc1ccc(-[n+]2nc(-c3ccccc3)nn2-c2ccccc2)cc1 +CCCC1c2ccccc2C=NN1C(=O)C=Cc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC +CC(=O)Nc1nc2c(Oc3cc(N4CCN(C(C)c5ccc(C(F)(F)F)cc5)CC4)ncn3)cccc2s1 +O=c1c(Oc2ccc3c(c2)CCC3)c(Cl)cnn1Cc1cccc2ccccc12 +Nc1ncnc(N2CCC(c3nc(-c4ccc(F)c(C(F)(F)F)c4)cn3CCN3CCCC3)CC2)c1-c1ccccc1F +CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)N(C)C(Cc1ccccc1)NC(=O)CNC(=O)C(C)c1ccccc1 +CCS(=O)(=O)c1ccc(Oc2ccc(C#N)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +COc1ccc(C(=O)N2CCCC(c3cc(C)nc4ncnn34)C2)cc1C +CCCCCOc1cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc2n1 +COc1ccc(OC)c(Cc2cc3c(Nc4cccc(Br)c4)nc(N)nc3[nH]2)c1 +O=C(NC1CCCN(Cc2cccc3ccccc23)C1)N1CCc2[nH]nc(-c3ccc4nccn4c3)c2C1 +CC(=O)C1CCC2C3CCC4CC(O)C(N5CCSC(C)(C)C5)CC4(C)C3CCC12C +CC(C)(C)N(NC(=O)c1ccccc1)C(=O)c1ccccc1[N+](=O)[O-] +CC1OC(=O)C2CC3CCC(O)CC3C(C=Cc3ccc(-c4cccc(C(F)(F)F)c4)cn3)C12 +N#Cc1cc(Cl)cc(Oc2cc(OCc3noc4ncccc34)ccc2Cl)c1 +O=S(=O)(Nc1ccc(F)cn1)c1cc(Cl)c(Oc2ccc(Cl)cc2C2CCNCC2)cc1F +COc1ccc(COc2nccc(-c3ccc4nc(NC(C)=O)sc4c3)n2)cc1 +Cn1c(COc2cccc(C#N)c2)nc(N2CCNCC2)cc1=O +CCc1cccc(NC(=O)Nc2ccc(Oc3ccc4nc(NC(=O)OC)[nH]c4c3)cc2)c1 +Cc1c(C(=O)O)oc2cccc(OCc3ccc4nsnc4c3)c12 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2cc(N3CCOCC3)ncc2[nH]1)C(F)(F)F +O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(F)c(-c2ccncc2)c1 +COCCOCC(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1 +NC1CC(c2ccncc2NC(=O)c2ccc(F)c(-c3ccccc3F)n2)CCC1O +COc1ccccc1C1CCC(N2CCN(c3ccccn3)CC2)CC1 +CN1C(=O)N(c2ccc(C#Cc3ccccc3)cn2)CC12CC2 +Nc1c2c(cc3c1C(c1ccc(Cl)cc1)c1c(-c4ccccc4)n[nH]c1O3)CCCC2 +Cn1c(=O)c(Cc2ccc(C(=N)N)cc2)nc2cc(C3(N(C(=O)CC(=O)O)C4CCCC4)CC3)ccc21 +N#Cc1cccc(-c2nc(N)c3cc(CN4CCSCC4)sc3n2)c1 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(OCCCCN(C)C)cc2)nc1 +Cn1cccc(Nc2n[nH]c3ccnc(OC4CCOCC4)c23)c1=O +COc1cc(-c2cnc(C)n2C)ccc1Nc1ncc2cc(C)nc(NCC(C)(C)OC)c2n1 +CC1C(NC(=O)OCCCCC2CCCCC2)C(=O)N1Oc1ccc(-c2ccccc2)cc1 +CC(C)CCN1C(=O)C(C2=NS(=O)(=O)c3ccccc3N2)=C(O)C1C(C)(C)C +COc1cc2c(cc1O)-c1n[nH]c(-c3ccc(-c4ccc(O)cc4)cc3)c1C2 +COc1ccc(Cl)cc1-c1nc(N)cc(Nc2ccc(Br)cc2)n1 +O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(C4CCCCO4)cc3)c(F)c12 +CCC(=O)N1CC(C(=O)N2CCN(c3ccc(C)cc3C(N)C(C)C)CC2)C(c2ccc(Cl)cc2)C1 +Cc1nc(-c2ccccn2)nc(NCC(NCCCCN2CCN(CCO)CC2)c2ccccc2)c1Cl +CC(Oc1cc(-n2cnc3cc(-c4cnn(C)c4)ccc32)sc1C(N)=O)c1ccccc1C(F)(F)F 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+O=C(CCCN1CCN(Cc2ccc(Cl)c(Cl)c2)CC1)Nc1ccc(Cl)cc1Cl +NC(Cc1cc(F)c(F)cc1F)C1CCN(C(=O)c2cnc3ncccn23)CC1 +CNC(=O)C(NC(=O)c1ccc(-c2ccc(NC(=O)c3cc4ccccc4o3)cc2)o1)C1CCCCC1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1ccc(CN2CCOCC2)cc1 +O=C(c1ccccc1-n1nccn1)N1C2CCC1C(COc1ccc(F)cn1)C2 +N=C(N)SCc1cccc2c1=c1c(CSC(=N)N)cccc1=2 +Cc1cc(C#Cc2cn(C3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)ccn1 +Fc1ccc(C=CCN2CCC(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +CCCCCCCCC=CCCCCCCCC(=O)c1nc2ncccc2o1 +O=C(Nc1cccc(-c2cnc(-c3c[nH]c4cc(F)ccc34)[nH]2)c1)c1cccnc1 +Cc1noc(-c2sc(NC(=O)c3ccccc3)nc2-c2ccccc2)n1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCn3ccnc3)c3ccccc23)cc1 +Nc1ncnc2nc(-c3ccc(N4CCC(O)(C5CCOC5=O)CC4)nc3)cc(-c3cccc(Br)c3)c12 +[C-]#[N+]C1(C)C(C)CC2CC(C)C3CCC(C)(N=C=S)C4CCC1C2C34 +COc1ncc(Cl)cc1-c1ccc2cc(C(=O)c3cnn(-c4ccc5[nH]c(C)nc5c4)c3N)[nH]c2c1 +O=C(Nc1cnn(S(=O)(=O)c2cc(Cl)ccc2Cl)c1)c1ccccn1 +O=C(OCc1ccccc1)N1CCCC1c1cc(-c2ccncc2)c(-c2ccc(F)cc2)[nH]1 +Nc1nc2c(cnn2CCN2CCN(c3ccccc3F)CC2)c2nc(-c3ccco3)nn12 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+N#CCCNC(N)=NC(=O)Cn1c(-c2ccccc2)ccc1C12CC3CC(CC(C3)C1)C2 +CCCN1CCN(c2cc(-c3ccc(Sc4ccc5c(c4)OCCO5)c(C(F)(F)F)c3)ccn2)CC1 +CC(C)(C)c1cc(Br)ccc1N1CCN(C(=O)CC(=O)O)CC1 +O=c1c(Cl)c(N2CCCCC2)cnn1-c1nc2ccccc2[nH]1 +CCCCc1ccc(Nc2nc(C(C)(C)C(=O)O)cs2)cc1 +Cc1ccc(-c2cc(C#N)ccc2COCc2cncn2Cc2ccc(C#N)cc2)cc1C +CN(C(=O)CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccnc(N)c2)CC1 +COc1cc2c(Nc3ncc(CC(=O)Nc4cccc(F)c4F)s3)ncnc2cc1OCCCN1CCCC1CO +COc1ccc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +O=[N+]([O-])c1cc(C(F)(F)F)cc([N+](=O)[O-])c1Oc1ccccc1C=NOCc1ccc(Cl)cc1Cl +CC1CCN(CCOc2ccc(C#Cc3ccc(-c4ccc(Cl)cc4)cn3)cc2)CC1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCc1nnn[nH]1 +COc1cc(COc2c(C)cccc2-c2csc(N3CCC(C(=O)O)C(OC)C3)n2)cc2c1CN(C1CCOCC1)CC2 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NC(=O)Cc1cc(N)ccc1-2 +C=CS(=O)(=O)Nc1ccc(-c2nn(C(C)C)c3ncnc(N)c23)cc1 +COc1cc2oc(=O)cc(-c3ccccc3)c2cc1OC(=O)Cc1cccs1 +CCN(C(=O)C1=CCCC1C(=O)NCc1ccc(C(=N)N)cc1)C1CCCCC1 +C=CC(=O)Nc1cccc(Nc2nc(NN=Cc3ccc(F)cc3)ncc2Cl)c1 +CCCCCCCN(CCOCCSc1nc(-c2ccc(OC)cc2)c(-c2ccc(OC)cc2)[nH]1)C(=O)NC(C)C +CNC(=O)c1cc2c(Oc3ccc(-c4ccco4)cc3)cncc2s1 +CC(F)(F)c1nc2ccccc2n1Cc1ccc(C(=O)NC2CCOCC2C(=O)NO)cc1 +CCCN(CC1CC1)c1cc(C(O)c2c(CC)cc(CC)cc2CC)nc(C)n1 +CCCCC(C)CC(C)C(=O)N(C)C(CC(C)C)C(=O)NC(C(=O)N(C)C(C(=O)OC)C(C)C)C(C)OO +Fc1cccc(Cl)c1-c1nc2c3cc(Cl)ccc3c3ccccc3c2[nH]1 +O=C(Nc1ccc(F)cc1)Nc1ccc(C=CC(=O)c2ccccc2)cc1 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccc(F)cc2)c1)C(F)(F)F +CNC(=O)c1c(F)cc(F)cc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +CN1C(=O)CCc2cc(-c3cncc4c3CCCC4=O)ccc21 +Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CN(C)C4CCOCC4)cc2)CCC3)cc1 +Cc1cc(C)c2ncc(NC(=O)Nc3ccc(F)cc3F)c(-c3ccccc3Cl)c2c1 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(OC(F)(F)F)c4)c3)cc12 +Cc1nn(Cc2ccc(NC(=O)c3ccc(C(C)(C)C)cc3)cc2)c(C)c1CCC(=O)O +CN(C)Cc1ccc(CSCc2ccc(-c3ccc(CSCc4ccc(CN(C)C)o4)cc3)cc2)o1 +Cc1c2c(n(-c3ccc(Cl)cc3Cl)c1-c1cccc(C(F)(F)F)c1)CCN(C1CCCCC1)C2=O +CC1(C)c2cc(N3CCC(N4CCOCC4)CC3)c(Cl)cc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +COc1cccc(C(=O)Cn2c3c(sc2=N)CCCC3)c1 +O=C(NCCCCCCc1ccccc1)Oc1cccc(N2CCNCC2)c1 +O=C(CNc1ccc(F)cc1)NN=Cc1c(O)ccc2ccccc12 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)cc1-c1cccc(C(F)(F)F)c1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cccc(S(=O)(=O)NCc3ccc(C(=O)O)cc3)c2)c1 +Cc1ccc(-c2ccccc2)c(C(=O)N2CCC2c2nc(-c3ccccc3OC(F)(F)F)no2)c1 +CCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC +Cc1nn(C)c(C)c1N(CC(F)(F)F)S(=O)(=O)c1c(Cl)cc(CCCCC2CCN(C)CC2)cc1Cl +NC(=O)OCC(CNC(=O)Cn1nc(-c2ccc(Cl)cc2)n(CC(O)C(F)(F)F)c1=O)c1ccccc1C(F)(F)F +Cn1c(CN2CCN(c3ccccc3C(F)(F)F)CC2)nc2ccccc21 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4CCOC4C3)n2)cc1C(F)(F)F +Cc1noc(C)c1-c1ccc2c(c1)C(c1ccsc1)(N1CCCC(N)C1)C(=O)N2 +CCCN(Cc1ccc(OCCn2c(=O)ccn(C)c2=O)c(C)c1)C(CC(=O)O)c1ccc2c(c1)CCO2 +Cc1cccc2c3c(ccc12)C1=C(C(=O)C3=O)C(C)CO1 +CCN(CC)C1CC(c2ccc(Cl)c(Cl)c2)c2ccc(O)cc21 +CCOC(=O)C(Cc1cc2ccnc(N)c2cc1OC)N1CCC(NS(=O)(=O)c2cnc(N3CCC(F)(F)C3)s2)C1=O +O=C(O)C(C1CCN(C(=O)C=Cc2cc(F)c(F)c(F)c2)CC1)N1CCC(c2c[nH]c3ccccc23)CC1 +COc1cc(I)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)OCCO[Si](C)(C)C(C)(C)C)n1 +NC(=O)N(O)CCON=Cc1ccc(Oc2ccc(F)cc2)o1 +O=C(O)c1ccc(N2CC3(CCN(Cc4cn(-c5ccc(F)cc5)nc4-c4ccc(F)cc4)CC3)OC2=O)cc1 +Cc1cnc2c(c1)C1c3cc(O)c(O)cc3CCC1NC2 +O=C(COc1ccc2[nH]c(-c3ccc(Cl)s3)nc2c1)Nc1ccc(N2CCOCC2=O)cc1 +O=C(NC1c2ccccc2CC1c1ccc(O)cc1)C(c1ccccc1)c1ccccc1 +O=S(=O)(Nc1cc(-c2cccs2)nn1-c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ccc(S(=O)(=O)NC2CCC(CCN3CCC(c4coc5ccccc45)CC3)CC2)cc1 +Cc1cc(OCCCN2CCCC2C)ccc1C(=O)CN1CCOCC1 +Cc1nc(Nc2ccc(F)c(Cl)c2)c2cc(NC(=O)CCN(C)C)ccc2n1 +CC1=C(C=CC#Cc2ccc(C(=O)O)cc2)C(C)(C)CCC1 +CN(C)C(=O)C1Cc2ccccc2N1C(=O)CCN1CCN(c2ccccc2)CC1 +Cc1c(C)c2c(c(C)c1O)CCC(C)(C(=O)Nc1ccc(NC(=O)CCCCC3CCSS3)cc1)O2 +O=C(Nc1ccc(CC2CCC(C(O)c3cccnc3)N2)cc1)C1CCc2sc(C3CC3)nc21 +CC(NC(=O)c1c(C(F)F)nn(C)c1Oc1cccc(C(F)(F)F)c1)c1ccc(C(=O)O)cc1 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccc(Br)cc3)CC2)n1 +COc1cc(OCc2cccc(OCc3ccc(F)c(C(F)(F)F)c3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CC1(C)CN(Cc2ccccc2)C(=O)C1Oc1ccc(C#N)c(C(F)(F)F)c1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1C)CC2 +COc1cc(OC)cc(Oc2ccncc2-c2n[nH]c(Nc3ccc4c(c3)OCCO4)n2)c1 +CN1CCN(CCCN(c2nc3cc(Cl)c(Cl)cc3[nH]2)C2CCC3(c4cccc(C#N)c4)CC23)CC1 +Cc1ccnc(NCC2CCN(c3ccc(CC(NC(=O)C4(C)CCCCC4)C(=O)O)cc3)CC2)c1 +Cc1cc(CNc2c(C)ccc(OCC(=O)O)c2C)cc(-c2cccc(F)c2)c1 +O=C(NCc1ccccc1)NC1CC2CCCC(C1)N2Cc1ccccc1 +COc1ccc(C2=NN(Cc3ccccc3)C(=O)C3CCCCC23)cc1OC +CC(=O)C1CCC2(C(=O)O)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +Cc1cn(C2CCCN(S(=O)(=O)c3ccc(C(N)=O)c(Oc4cccc(Cl)c4)c3)C2)c(=O)[nH]c1=O +COc1cc(F)cc(N(CCNC(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C(NC1CCCCC1)N1CCN(C(c2ccc(Br)cc2)c2ccccc2Cl)CC1 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(O)C5)cn3)n2)s1 +CC(Oc1cc(-n2cnc3cc(-c4cnn(CCN5CCN(C)CC5)c4)ccc32)sc1C(N)=O)c1ccccc1Cl +CC(C)n1cnc2c(NC(=N)N)nc(NCCCO)nc21 +CC(CCc1ccc(-c2ccc3c(c2)CNC3=O)cc1)(C(=O)NO)S(C)(=O)=O +CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCN(C)CC4)nc3)c2n1 +Cn1cc2c(nc(NCc3ccc(C(F)(F)F)cc3)n3nc(-c4ccco4)nc23)n1 +O=C(Nc1ccccc1N1CCNCC1)c1csc(C#Cc2ccccc2)n1 +Cc1nc2ccccc2c(=O)n1CCCCCN1CCN(c2ccc(Cl)cc2)CC1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(C(C)CC)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(C#N)cn3)CC2)CC1c1ccc(Cl)c(F)c1 +CC(NC(=O)C(NC(=O)c1ccc2ccccc2c1)C(C)C)C(=O)NC(CC(=O)O)C(=O)COc1ccccc1 +Cc1cccc(-c2nc(C(F)(F)F)ccc2CNC(=O)Nc2ccc(CNS(C)(=O)=O)cc2)c1 +CCOC(=O)C1=C(C)OC2OC(COCc3ccccc3)C(OCc3ccccc3)C(OCc3ccccc3)C2[S+]1[O-] +O=C(O)c1cccc(S(=O)(=O)Nc2ccc3ccccc3c2)c1 +COc1ncnc(Cn2cc(C(=O)NCC(C)F)c3ncc(C)cc32)c1C +COc1ccc(O)c(C(=O)CC(=O)c2ccc(F)cc2)c1 +COc1cc(Oc2ccnc3cc(OC)c(OC)cc23)ccc1CC(=O)Nc1noc(C)c1C +CN(c1ncnc2[nH]ccc12)C1CCC(CS(=O)(=O)N2CCC(Cc3cnccn3)C2)CC1 +COc1ccc(NC(=O)N2N=C(c3ccc(Br)cc3)CC2c2ccc(F)cc2)cc1 +CNCCCNc1nc2c(C)cc(C)cc2n1Cc1nc(C)ccc1O +C=CCC(O)C1CCCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C +O=C(NC1CCN(CCO)CC1)c1cc2ccccc2n1Cc1cc(-c2ccc(Cl)s2)on1 +c1ccc(C2(c3ccccc3)CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)cc1 +O=C(NCCC1CCN(C(=O)C=Cc2cc(Cl)cc(Cl)c2)CC1)c1c[nH]c(=O)o1 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+O=C(NCC1(O)COC(CN2C(=O)c3ccccc3C2=O)C1O)c1ccccc1Cl +Cc1cccc(-c2ccc3c(O)oc(=O)c(C(=O)NCC(=O)O)c3c2)c1 +O=c1[nH]c2c(O)ccc(C(O)CNC3CCCC3C3CCCCC3)c2s1 +CC(NC(=O)c1cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CC2)cc2c1CCCO2)c1ccccc1 +Cc1[nH]c(C(=O)NC2CCN(c3ncc(C(=O)O)s3)CC23OCC(C)(C)CO3)c(Cl)c1Cl +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(S(=O)(=O)N3CCOCC3)CC2)cc1 +CC(C)C(=O)N1c2cccc(O)c2NC2=C(C(=O)CC(C)(C)C2)C1c1ccc(OCc2ccccc2)cc1F +COc1cccc(CN(C)C(=O)c2cc3c(Cc4ccccc4)n[nH]c3cc2O)c1 +CCCCCn1cc(C(=O)NN(C)C)c(=O)c2ccc(Sc3ccccc3)cc21 +CCS(=O)(=O)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1C#N +Cc1c2c(n3c1CCN(CCC(C)C)c1cc(C(N)=O)c(Cl)cc1-3)CC(C)(C)CC2=O +OCC(O)CN1C(CCc2cccc3ccccc23)CCCC1CCc1cccc2ccccc12 +CNc1nccc(-c2cccnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)ccc2Cl)n1 +CCCCCC#CCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3ccc(Br)cc3)CC2)cc1 +Cc1ccc(-c2nc3cc4c5c(cccc5c3s2)C(=O)N(CCN(C)C)C4=O)cc1 +CC(=O)OCCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 +c1cc(N2CCCN(c3ccc(C4=NCCN4)cc3)CC2)ccc1C1=NCCN1 +COc1ccc(-c2oc3c(OC)c(OC)c(OC)cc3c(=O)c2OC)cc1N +O=C(CCc1ccccc1)c1cc(OCc2ccccc2)ccc1OCC(O)CN1CCN(Cc2ccccc2)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]c(-c4ccc(Br)cc4)nc3c2)c1F +Cc1ccc2cccc(NCc3ccc(C(=O)NO)cc3)c2n1 +CS(=O)(=O)CCCOc1cccc2c1ccn2-c1ccnc(NC2CCC(C(=O)N3CCC(O)CC3)CC2)n1 +COc1cc(C)cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncccn5)ccc43)cc2C)c1 +C=CC(=O)N1CCCC(Oc2nc(Nc3ccc(N4CCC(N5CCN(C)CC5)CC4)cc3)c(C(N)=O)nc2CC)C1 +CCC(CC)OC1C=C(C(=O)Nc2ccccc2)CC(NC(=O)OC(C)(C)C)C1NC(C)=O +C#CCN(Cc1cc2c(O)nc(C)nc2cc1C)c1ccc(C(=O)NC(CCCCC(=O)O)C(=O)O)c(F)c1 +COC(=O)c1c(C(F)(F)F)[n+]([O-])c2ccc(N3CCN(c4ccc(F)cc4)CC3)cc2[n+]1[O-] +COCC(=O)N(Cc1cc(C(=O)NOCCO)c(Nc2ccc(I)cc2F)c(F)c1F)OC +CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)C1CN(C(=O)c2ccncn2)CC1c1ccccc1 +CC(C)c1cc(Oc2c(Br)cc(CCC(=O)O)cc2Br)cc(C=Cc2ccncc2)c1O +CCC=Cc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)O)n2Cc1cc(F)ccc1F +Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN3CCCC(C)(C)C3)cc2)c2ccc(O)cc12 +CN1CCN(c2ccc(Nc3cc(-c4nc(NC5CCNC5)c5sccc5n4)ccn3)nc2)CC1 +COC(=O)c1cccc(-c2cc(N3CCN(C(=O)c4ccoc4)CC3)n3nc(-c4cccc(OC)c4)cc3n2)c1 +CCC(N)C(=O)NC1C(=O)N2C(CCC1CNC(=N)N)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +Clc1cccc(-[n+]2nc(-c3ccccc3)nn2-c2ccccc2)c1 +CN1CCN(S(=O)(=O)c2ccc(-c3cnc(N)c(C(=O)Nc4cccnc4)c3)cc2)CC1 +Cc1cn(C2CCCN(Cc3cccc(Oc4cccc(F)c4)c3)C2)c(=O)[nH]c1=O +COc1ccc2cc3[n+](cc2c1OCC=C(C)CCC=C(C)CCC=C(C)C)CCc1cc2c(cc1-3)OCO2 +N#Cc1ncc(F)c(N(Cc2ccc3c(c2)OCO3)CC2CCCC2)n1 +CCOc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCC2)[nH]1 +O=C(c1ccc([N+](=O)[O-])o1)N1CCN(c2nc3ccc(F)cc3s2)CC1 +COCC(O)Cn1cc(-c2ccc3c(c2)N(C2=NC4CC(C)(C)NC(=O)C4S2)CCO3)cn1 +CN(c1ccccc1Cl)S(=O)(=O)c1ccc(NC(=O)c2nccs2)cc1 +CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2c(F)cccc21 +[O-][S+](Cc1nccc(OCC(F)(F)F)c1OCC(F)(F)F)c1nc2cscc2[nH]1 +CC1CCNC(=O)c2cc3ccc(C(=O)Nc4cnn(Cc5ccccc5)c4)cc3n21 +COC(=O)c1cc(O)cc2nc(-c3ccc(O)cc3)oc12 +COc1ccccc1N1CCN(CCCCOc2c(C)cccc2C)CC1 +COCCC1N=C(c2ccc(Cl)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +COc1cc2c(cc1OC)C(=O)N1C=C(c3cccc(N)c3)CC1C=N2 +CN(C)c1ccc(C=CNNC(=O)CCCCCC(=O)NO)c(O)c1 +COC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccc(OC)c(OC)c3)C2)C1c1cccc(Cl)c1Cl +COc1ccc(CCc2cnc3c(N)nc4cc(CCP(=O)(O)O)ccc4c3c2)c(C)c1 +O=S(=O)(N1CCc2cc(O)ccc2C1)C(F)(F)F +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N(CCO)S(C)(=O)=O)no2)cc1C#N +CCN1CCCN(C(=O)C(Cc2ccccc2)c2ccccc2)CC1 +CC(=CC(C(C)C)N(C)C(=O)C(NC(=O)C(NCCO)C(C)(C)c1ccccc1)C(C)(C)C)C(=O)O +COc1cccc(-c2ccc(C(=O)N3CCN(C(=O)c4ccc5cc[nH]c5c4)C(C)C3)cc2)c1 +CCS(=O)(=O)N(CC(O)C(=O)NO)c1ccc(Oc2ccc(C)cc2)cc1 +CC12CCC(O)CC1=CCC1C2CCC2(C)C(n3ccnc3)=CCC12 +CCCC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NO +CCCN(CCC)CCCOc1cc(C)nc(-c2ccccc2)n1 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nc12 +CCC1CC2=CC(=O)CCC2C2CCC3(CC)C(CCC34C=CC(=O)O4)C12 +CCCN(CCC)C1COc2c(cccc2C(=O)c2ccc(OC)cc2)C1 +NS(=O)(=O)c1ccc(CC[n+]2c(-c3ccccc3)cc(-c3ccccc3)cc2-c2ccccc2)cc1 +O=C(Nc1ccc(C(=O)O)c(O)c1)NC12CC3CC(CC(C3)C1)C2 +CS(=O)(=O)c1csc(NC(=O)c2ccccc2O)n1 +N#Cc1cnc2sc3c(c2c1Nc1ccc(Cl)c(Cl)c1)CCN(C(=O)C=CCN1CCCOCC1)C3 +CCc1nc2c(-c3ccc(Cl)cc3C)nccc2n1C(CC)C1CC1 +COC1CC2CCC(C1)N2c1nc(N2CCCC(C(N)=O)C2)c2c(-c3ccccc3Cl)csc2n1 +CC(C)(C)C1=CSC(=C(C#N)c2ccnc(NC(=O)C3CCNCC3)n2)N1 +CCN(CC)c1ccc(CN(C(=O)Cc2ccccc2)C23CC4CC(CC(C4)C2)C3)cc1 +OCc1cncc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC3)n2)n1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5CCC(C4)N5C)cn3)nc2n1C1CCCC1 +CC(=O)c1cc(NC(=O)NC(C)CCN2CCCC(Cc3ccc(F)cc3)C2)cc(-c2nnnn2C)c1 +CC1CN(C(=O)N2Cc3c(-c4ccc(F)cc4)ncn3-c3cccc(Cl)c32)CC(C)N1C +COc1ccc2[nH]c(C(=O)NC3N=C(c4ccccc4F)c4ccccc4NC3=O)cc2c1 +COc1ccc2c(c1)c(C=C1C(=O)Nc3ccc(C(=O)O)cc31)cn2C +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C12CN(c1ccc(C#N)cn1)CC2c1ccc(C#N)cc1 +Nc1ncc(-c2nc(N3CCOCC3)nc3c2CCN3C2CCN(S(N)(=O)=O)C2)cn1 +CCN(CC)c1ccc(OC)c2nc(-c3c(OC)cc(COC)cc3OC)c(C)cc12 +CC(=O)NC(CCN1C2CCC1CC(n1c(C)nc3c1CNCC3)C2)c1ccccc1 +Cc1nc(C=Cc2c(C)nnn2-c2ccc(F)cc2)sc1C(=O)NC(C)C +Cc1cc(-c2cnn3ccc(N4C(=O)OCC4C(C)C)nc23)ccc1-c1nc[nH]n1 +O=C(CCC(NS(=O)(=O)c1ccc(-c2ccc(Br)cc2)cc1)C(=O)O)NC1CCCCC1 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+O=C1NC(=O)C(c2cncc3ccoc23)=C1c1cn2c3c(cccc13)CNCC2 +C#CCNc1nc(Nc2ccc(S(N)(=O)=O)cc2)ncc1Br +O=C(O)c1ccc(NC(=O)c2ccc3c(c2)N(Cc2cccc(Cl)c2)C(=O)CS3(=O)=O)cc1 +O=C1NCN(c2ccccc2)C12CCN(C1COCCC1(O)c1ccccc1)CC2 +O=[N+]([O-])c1ccc2nc(-c3ccccc3O)[nH]c2c1 +COc1cc2c(cc1NS(=O)(=O)c1cccc(Cl)c1Cl)[nH]c(=O)n2C +O=C1OCC(C2CCCC2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(-c2cn[nH]c2)cc1F +CSc1ccc2c(c1)CCC2C(CS)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +CC1CN(C(=O)C(C)(O)C(F)(F)F)CCN1S(=O)(=O)c1ccccc1 +CC(C)CCC#Cc1cc2c(cc1N1CCN(C3COC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +COc1cccc(-c2ccc3c(c2)Nc2ccccc2NC3=O)c1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(-c2ccccc2Cl)cc1F +O=C(NCc1ccc(F)cc1)C1C(=O)N(O)C(=O)c2cc(Br)ccc21 +COc1cc(-c2ccncc2)cc2cnc(Nc3ccc(C(C)NC(C)=O)cc3)nc12 +CCNC(=O)C1OC(n2cnc3c(N)[n+](Cc4ccccc4[N+](=O)[O-])cnc32)C(O)C1[O-] +OCC1CC(Nc2nc(Nc3cncnc3)ncc2-c2nc(-c3ccccc3)cs2)C(O)C1O +COc1cc(-c2cn(C3CCc4c(F)cccc4N(CC(F)(F)F)C3=O)nn2)ccc1-n1ccnc1C 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+O=C(O)c1ccc(CNc2ccc3c(C=Cc4cccc(C(F)(F)F)c4)cccc3c2)cc1 +O=C(COc1cccc2[nH]cc(S(=O)(=O)c3ccccc3Cl)c12)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +CCCC(C)(O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 +CCN(CC)CCCCNC(=O)C1C(C(=O)NCc2ccc(Br)cc2)C2C=CC1C21CC1 +CC(C(=O)O)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 +CCN1CCN(c2cccc3c2CN(C(CCCNS(=O)(=O)c2c[nH]cn2)c2ccc(OC)c(OC)c2)C3=O)CC1 +O=C(NC(Cc1ccc(CCCCNc2ccccn2)cc1)C(=O)O)c1c(Cl)cccc1Cl +O=C(C=Cc1cccc2c1N(Cc1ccc(F)c(F)c1)C(=O)C2)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +O=C(Nc1ccc(F)c(OCCCN2CCOCC2)c1)NC12CC3CC(CC(C3)C1)C2 +CC(NC(=O)c1nn(-c2ccc(C(F)(F)F)cc2Cl)c2c1CCCCC2=Cc1ccc(Cl)s1)c1ccccn1 +NC(Cc1cccc(F)c1)C(=O)Nc1ccc(-c2cn[nH]c2)cc1 +Nc1[nH]cnc2c(CN3CC(O)C(CSCc4ccccc4)C3)cnc1-2 +CC(C)N1CCCN(C(=O)C(Cc2ccccc2)c2ccccc2)CC1 +COC(c1ccccc1)c1ccc(-c2nc3cc(C(N)=O)ccc3[nH]2)cc1 +Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)N1CCN(S(C)(=O)=O)CC1 +CN1CCN(c2ccc(Nc3nc4cccc(-c5ccc(NS(C)(=O)=O)cc5)n4n3)cc2)CC1 +O=C(O)CC1(Cc2nc3cc(F)ccc3n2Cc2ccc(Cl)cc2)CCCC1 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+COc1ccc(CCNCC(O)COc2ccc(-c3nc(C(C)(C)C)c[nH]3)cc2)cc1OC +CC(C)(C)C1CCc2onc(C(=O)Nc3cnn(Cc4ccccc4)c3)c2C1 +COC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(C)C +C=CC(=O)N1CC(Oc2cc3c(NC(C)c4ccccc4)ncnc3cc2OC)C1 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(F)cc1 +CCCN(CC1CC1)c1nc(CC)c(-c2ccc(Cl)cc2Cl)nc1CC +Cc1cccc(-c2nc3c(NC4CC(O)C(COS(N)(=O)=O)C4)ncnc3[nH]2)c1C +N#Cc1cnc2[nH]cc(C(=O)c3cccc(NS(=O)(=O)c4c(F)cccc4F)c3F)c2c1 +CN(C)CCOc1ccc2c(c1)Nc1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn1CC2 +CC1Cc2c(ccc(F)c2Cl)N1C(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1 +CCN(C)C(=O)c1ccc(C(c2cccc(NC(=O)C3CCC3)c2)N2CCN(Cc3cccnc3)CC2)cc1 +Cc1nn(-c2ccccc2)c(Cl)c1CN1CCN(c2ccc(F)cc2)CC1 +CC(C)CC(NC(=O)Nc1ccc(Br)cc1)C(=O)NC(C)(C)C(=O)O +CCCN(Cc1ccc2ccccc2c1)c1ccc2nc(N)nc(N)c2c1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(N)Cc3ccccc3)c2=O)c1F +CCCCCCCC(=O)Nc1nn(C)c2ncnc3c2c1cn3C1OC(CO)C(O)C1O +O=C1c2cc3c(cc2C2(CC2)N1CCC1CCN(Cc2c(F)cccc2F)CC1)OCO3 +COc1cc(C#CC2CCCC2)c(F)cc1-n1c(=O)cnc2cc(S(=O)(=O)Nc3ccon3)ccc21 +O=C(O)C1CCC2(CCN(c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)CC2)CO1 +CCc1[nH]c2nc(Sc3ccc4ccc(C(=O)O)nc4c3)nc(N3CCC(N)C3)c2c1Cl +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCCc4ccccn4)nc23)N1 +COc1ccc(C(c2ccncc2)c2cc3c4c(c2)CCN4C(=O)CC3)cc1 +CCCn1c(=O)c2nc(-c3cc(OCC(=O)Nc4ccc(OC)c(OC)c4)nn3C)[nH]c2n(CCC)c1=O +O=C(CN1CCCCC1)Nc1scnc1C(=O)Nc1nccs1 +O=C(O)Cn1c(=O)c(C=Cc2ccc(F)cc2)nc2cc([N+](=O)[O-])ccc21 +Cn1ncc2cc(-c3cccc(OCC(O)CN4CCc5ccccc5C4)c3)ccc21 +CC(C)C(NC(=O)COc1cc2ccccc2cc1C(=O)O)C(=O)NC1CC(=O)OC1O +CCCCCCn1c(C)c(C(=O)c2cccc3ccccc23)c2ccccc21 +Cc1cc(CSc2nnc(Nc3ccc(Cl)cc3)[nH]2)no1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(N2CCCC2)nc1C +Oc1cc2c(cc1O)C1c3cc(-c4ccccc4)sc3CNC1CC2 +Nc1ncc(CN2CCc3c([nH]c4ccccc34)C2)c(N)n1 +COc1ccc(NC(=O)Nc2nc3nn(C)cc3c3nc(-c4ccc(Br)cc4)nn23)cc1 +O=C(NC(Cc1ccc2nc(-c3cc(C(F)(F)F)ccc3Cl)ccc2c1)C(=O)O)c1c(Cl)cccc1Cl +Cc1ccc(C(=O)N2CCc3c(cc(Cl)c(C(=O)NC(CNC(=O)c4cccs4)C(=O)O)c3Cl)C2)cc1 +COc1ccc(NC(=O)c2cc3n(n2)CCCN(C(=O)c2occc2C)C3)cc1 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+CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3cccc(CN(C)C(=O)C(F)(F)F)c3)nc2n1 +CC1(CO)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 +CN(C)C(=O)CCN1CCN(CC2CC2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(Cl)c(Cl)c2)CC1 +CC(=O)NC1C(NC(=N)NC(=O)CCn2cc(-c3ccccc3)nn2)C=C(C(=O)O)OC1C(O)C(O)CO +Cn1c(=O)cc(N2CCCC(C)(N)C2)n(Cc2cc(F)ccc2C#N)c1=O +O=C(O)c1ccc(O)c(C(=O)C=Cc2ccc(C=Cc3ccc4ccccc4n3)cc2)c1 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cccc(F)c3)c(F)c2)CC1 +COc1cc(-c2c(-c3ccncc3)nn3c(-c4ccc(N5CC6CCC(C5)N6C)cc4)ccnc23)ccc1Cl +C=C(c1cccc(OCCCC)c1)C1CNC(C(=O)O)C1CC(=O)O +COc1cccc2c1CCC2C(CS)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +COc1cc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1C(=O)NCCCN1CCCCC1 +CCNC(=O)C1OC(n2cnc3c(NCc4ccco4)ncnc32)C(O)C1O +O=[N+]([O-])c1ccc(NCCOCCOc2cccc3c2CCCC3CCCN2CCN(C3CCCCC3)CC2)c2nonc12 +COc1ccccc1N1CCN(Cc2cn(-c3cccc4ccccc34)c3ccccc23)CC1 +CNC(=O)COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +COc1cc(-c2cc(C(=O)NC3CCCN(C(=O)C4(N)CC4)C3)c3c(N)ncnn23)ccn1 +CN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(c3ccccc3OC(F)F)=NN12 +CCCC(=O)Nc1n[nH]c2ncc(-c3cccc4ccccc34)cc12 +CCCCCCCCCC=Cc1cc2ccccc2n1C(=O)CCCC(=O)O +CCOn1c(Sc2ccccc2)c(CC)c(=O)[nH]c1=S +CCN1CCN(C(=O)c2cc(Sc3cnc(Nc4cccc(Br)n4)s3)ccc2C)CC1 +COc1cc(-c2ccc3c(-c4nc5c(N6CCN(C)CC6)cccc5[nH]4)n[nH]c3c2)ccc1O +O=C(Nc1ccn2cc(-c3ccc(F)c(F)c3)nc2c1)N1CCC(F)C1 +COc1ccc(C(=O)Nc2ccc(CCN3CCc4cc(OC)c(OC)cc4C3)cc2)cc1NC(=O)c1cnc2ccccc2c1 +[O-][n+]1nc2c(I)cnn2c2cc(-c3ccccc3)ccc21 +O=C(C1CCCN(c2ccc3nc(-c4cncc(C5CC5)n4)[nH]c3n2)C1)N1CCCC1 +CC(NC(=O)C(CS)Cc1ccccc1Cl)C(=O)N1CCCC1C(=O)O +O=C(Cn1ncc2ccccc21)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +CCc1cc(CC)nc(OCCCn2c3c(c4cc(C(=O)OC)ccc42)CCCC3)n1 +O=c1c2cc(O)c(O)cc2oc2cc(O)c(C3OC(CO)C(O)C(O)C3O)c(O)c12 +O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc4ccccc34)ccc1-2 +COc1ccc(-c2ccc(C(N)=O)cc2Cl)cc1OC1CCCC1 +CC(C)(C)CC(O)C(=O)N1CC2CC2C1C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +NC1=NC(=O)C2C(N=C(c3ccccc3)N2C2OC(CO)C(O)C2O)C(=O)N1 +COc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)cc2)c2ccccn2)CC1 +CCCc1c(OCCCCOc2cccc(C(=O)O)c2)ccc2c(-c3ccccc3)noc12 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+N=C(N)NCCCC1CC(OCc2ccc3ccccc3c2)CN1C(=O)C(Cc1ccccc1)NC(=O)CCc1ccccc1 +CN1CCC(COc2ccc3c(Nc4ccc(CC(=O)Nc5ccc(Cl)c(C(F)(F)F)c5)cc4)ncnc3c2)CC1 +O=C(Nc1cc(C2CN(C3CCC3)C2)nn1-c1ccc(C2CC2)cc1F)c1cnn2cccnc12 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc(-c4cccc(S(N)(=O)=O)c4)cn3)C12 +COc1ccc2c(c1)CC(C(=O)Nc1ccc(-c3c[nH]nc3C)cc1SCCN(C)C)NC2 +COc1cccc(COc2ccc3sc4c(c3c2)NCC(C)NC4=O)c1 +Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3cccnc3)nc21 +Cc1cc(C)nc(N2CC3CN(C(=O)c4cccc(F)c4-c4ccccn4)CC3C2)n1 +NC(=O)c1cccc2c(NCc3cccc(OCCN(CCO)CCO)c3)ncnc12 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccc(CC(=O)O)cc3)n2)CC1 +COc1cc(-c2cn[nH]c2)c(F)cc1NC(=O)C1COc2ccccc2C1 +O=C(c1cccc(-c2cccc(O)c2F)n1)c1ccc(F)c(O)c1O +Nc1ncc(-c2nc(N3CCOCC3)c3sccc3n2)cn1 +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cccc(N2CCN(c3ccc(O)cc3)CC2)n1 +CN(Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1)C1=NCCN1 +CCN(CC)CCCOC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3ccccc3C)c3ccccc23)CC1 +COc1ccc(C(C#N)(CCCNC2c3ccccc3CCc3ccccc32)C(C)C)cc1OC 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+O=C(C=Cc1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C21OCCO1)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +CC(C)(C)NC(=O)NC1CCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)C1 +Fc1cc(F)c(CNc2ccc(Oc3ccccc3C(F)(F)F)cn2)c(F)c1 +COC(=O)c1c(CNC(=O)c2cccc(F)c2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +CCCn1c(=O)c2nc(-c3cc(OCC(=O)Nc4ccc(OC)c(OC)c4)no3)[nH]c2n(CCC)c1=O +CC(C)(C)c1cc(C(=O)Nc2cccc(CN)n2)n(Cc2ccccc2)n1 +O=C(CCCN1CCN(c2ccc([N+](=O)[O-])cc2)CC1)NC1c2ccccc2CSc2ccccc21 +Cc1ccc2[nH]c(C)c(C=Cc3cc[n+](C)cc3)c2c1 +CC(C)OC(=O)c1oc(N)nc1-c1ccc(P(=O)(O)O)o1 +CC1(O)CCC(NC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(Cl)cc3Cl)n(-c3ccccc3)n2)CC1 +CCc1nc(Nc2ccc(C(=O)O)cc2)nc(-c2ccc(Cl)s2)n1 +CC(C)CCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O +CCCCN(CCCC)CCNCC(O)c1ccc(O)c2[nH]c(=O)sc12 +O=c1[nH]c(N2CCC(F)(F)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +O=C(O)Cc1ccc(F)c(-c2cccc3c2CN(C(=O)OCc2ccccc2)CC3)c1 +C=C(C)C1CCC2(NC(=O)NCCO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC(=O)N1CCC(n2cc(-c3cnc(N)c4oc(-c5cn(C)c6cnccc56)cc34)cn2)CC1 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+CCCCCCCCCCCCn1c2nc(=O)[nH]c(=O)c-2cc2c([N+](=O)[O-])cccc21 +CN(C)CCN1C(=O)c2c(N)ccc3cc4c(c(c23)C1=O)CCCC4 +Cc1cc(OCCC(C)Oc2ccc(C(F)(F)F)cc2Oc2ccccc2)ccc1CCC(=O)O +COCCNC(=O)c1cn2cc(-c3cnc(N)nc3)nc(N3CCOCC3)c2n1 +CC12C=CC(=O)C=C1C=CC1C2CCC2(C)C(=O)CCC12 +C=CCN1CC(C)N(C(c2ccc(C(=O)N3CCCC3)cc2)c2cccc(OC)c2)CC1C +O=C1Nc2ccc(-c3n[nH]c(C4CCCCN4C(=O)COc4ccccc4)n3)cc2CO1 +O=[N+]([O-])c1cccc(NN=Cc2cc([N+](=O)[O-])ccc2O)c1 +CN(C)Cc1ccc(C(=O)Cn2ncc(OCc3ccccc3)cc2=O)cc1 +CS(=O)(=O)c1cnc(OC2CCC(OC3CCN(C(=O)OC(CF)CF)CC3)CC2)cn1 +CCC(C)CNc1cc(-c2[nH]c(SC)nc2-c2ccc(F)cc2)ccn1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1cc(F)cc(F)c1)Oc1ccccc1-3 +O=C(CCCC1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)c1ncco1 +C#CC1(O)CCC2C3CCC4=Cc5nc6nc7ccccc7n6cc5CC4(C)C3CCC21C +Cc1ccc2nc3c(C(=O)NCCCN(C)CCCNC(=O)c4cccc5nc6cc(C)ccc6nc45)cccc3nc2c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(OCC4CC4)c3C)C2)cc1 +O=C(Nc1ccccc1)c1ccn(C(=O)c2ccccc2)n1 +CCCCCNC(=O)Nc1c(C)cccc1C[S+]([O-])CCn1cnc(-c2ccccc2)c1C +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2c(cnn2CCO)c1 +CCCOc1ccc(C(=O)C(CN2CCOCC2)c2ccccc2)cc1 +Cc1ccc(NC(=O)c2cc[n+](CCCCCCCCCC[n+]3ccc(C(=O)Nc4ccc(C)cc4)cc3)cc2)cc1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C5CCCC5)no4)c3)c2cc1OC +CCCCCn1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c(=O)cc1C +Cc1ccc(NC(=O)c2ccc(Cl)cc2)cc1Nc1nc(-c2cccnc2)c[nH]1 +O=C1NC(=O)C(c2cccc(OCCCOc3ccc(Oc4ccccc4)cc3)c2)S1 +Cc1cc(C)cc(NC(=O)c2cccnc2SCc2ccnc(C)c2)c1 +CC1CN(Cc2ccccc2)CC1c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1 +COc1cc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC4CCCN4CC2C)C3(C)C)nc(OC)n1 +N#CC1=C(c2cccc3ccccc23)CN(C(=O)CCc2cncn2Cc2ccc(C#N)cc2)CC1 +COc1ccc(C2(C(=O)NC(Cc3ccc(NC(=O)c4ccnc5ccccc45)cc3)C(=O)O)CCCC2)cc1 +Nc1nc2c(ncn2C=C2CC23CCP(=O)(O)OC3)c(=O)[nH]1 +CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2ccccc2)c1C(=O)OCC +O=P(O)(O)C(O)(Cc1cccc(Br)c1)P(=O)(O)O +CC(C)(C)N=c1c(O)c(O)c1=NC(Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)C(=O)O +CCC(Nc1ncnc(N)c1C#N)c1nc2cccc(C#CCCCC(=O)N3CCOCC3)c2c(=O)n1-c1ccccc1 +CN(CC1=Nc2c(N)nc(N)nc2N(Cc2ccccc2)C1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +NC(=O)c1cccc2[nH]c(-c3ccc(C4CCCCN4)cc3F)nc12 +CC(NC(=O)C(F)(F)F)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OC2CCC3(CCCCC3)CC2)cc1F +O=C(O)CCCCCCN1C(=O)CCC1C=CC(O)c1cccc(-c2ccccc2)c1 +CC(=O)N(C)CCCOc1ccc(C(=O)N2CCC(N3C(=O)CCc4ccccc43)CC2)cc1 +CON=C(c1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CCC2(C)C +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1ccc2c(ccn2C)c1 +C#CC1CCC(C#N)N1C(=O)CNC1(C)CCN(c2cc(C(=O)O)ccn2)CC1 +CCCCC(Sc1nc(OCCc2ccsc2)cc(OCCc2ccsc2)n1)C(=O)O +CN(C)C(=O)Cc1cc(-c2ccncc2)c(-c2ccc(F)cc2)[nH]1 +Oc1noc(C2CCNCC2)c1Cc1ccc2ccccc2c1Br +CCOc1ccc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)OCC3(F)F)c2)nc1 +COc1ccn2ncc(C=NN(C)S(=O)(=O)c3cc([N+](=O)[O-])ccc3C)c2n1 +O=C(O)C1CCCN(CCC=C(c2sccc2COc2ccccc2)c2sccc2COc2ccccc2)C1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(C4CC4)c3c2)c1F +CC(C)C(=O)N1CC(CC=CCCC(=O)O)C(c2ccccc2O)C1 +CS(=O)(=O)CC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)CC1CCC1 +CC(C)c1ccc(N2CCc3cc(O)ccc3C2(C)c2ccc(OCCN3CCCC3)cc2)cc1 +CC(C)(C)OC(=O)N1CCC(c2ccc(Cl)cc2)C(COc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)C1 +CCSC1=C(c2ccc(O)cc2)C(=O)c2ccc(O)cc21 +c1cc2c(c(-c3nc4cccnn4c3-c3ccncc3)c1)OCO2 +CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(-c3cccc(N)c3)ccc21 +COc1ccc2[nH]cc(CCCN3CCN(CCCc4c[nH]c5ccccc45)CC3)c2c1 +CC(=O)Nc1cccc(C2CCN(CCCC(=O)c3ccc(C)c(C)c3)CC2)c1 +Cc1ccc2c(NCCNc3ccnc4cc(C)ccc34)ccnc2c1 +CNC(=O)C(CC(C)C)CC(O)C(Cc1ccccc1)NC(=O)c1cncc(Br)c1 +C#CCOC(=O)CC1C(C(=O)OCC#C)=C(N)Oc2ccc(-c3cc(OC)cc(OC)c3)cc21 +C=CCN1C(=O)C(=C2Sc3ccc(OC)cc3N2C)SC1=Nc1ccccc1-c1ccccc1 +Nc1nc(-c2cc3c(s2)-c2ccccc2OCC3)c(-c2ccccc2Cl)s1 +CC(NC(=O)C1(Cc2ccccc2)OC(=O)N(C(C)c2ccccc2)C1=O)c1cccc(Cl)c1 +CNC(=O)C(NC(=O)C(CC(C)C)C(Sc1ccc2c(c1)CCC(=O)N2C)C(=O)NO)C(C)(C)C +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1cccc2ccccc12 +CC(=O)N1CCN(c2nccnc2OC2CN(C(=O)c3nc4ccccc4[nH]3)C2)CC1 +O=C(CC(NC(=O)c1ccc(C#Cc2ccccc2)cc1)C(=O)NO)NCCCO +CCCn1c(C)c(Cl)c2cc(Nc3nccc(-n4cc(CN5CC(O)C5)c(C)n4)n3)ccc21 +O=C(C=Cc1ccc([N+](=O)[O-])cc1)Nc1cc(-c2ccc(Br)cc2)[nH]n1 +O=C(NCCN1CCCC1)c1cc2cnnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2[nH]1 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+O=C(Nc1ccc(CC(NC(=O)C2CCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)C(=O)O)cc1)c1c(Cl)cccc1Cl +Cc1ccc(CCC(=O)NC23CCC(=O)C4Oc5c(O)ccc6c5C42CCN(C)C3C6)cc1 +COc1ccccc1-n1nc(OC2CC(C)(C)[S+]([O-])C(C)(C)C2)cc1-c1ccc(C#N)cc1 +Cc1cccc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c12 +O=C(CCN1CCCCC1)Nc1ccc2cc3ccc(NC(=O)CCN4CCCCC4)cc3nc2c1 +CC(=O)C1CC(NC(=O)C(N)CCCNC(=N)N[N+](=O)[O-])CN1 +Cc1c(CC(=O)OCCO)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccccc1 +CC(=O)N1CCc2c(ncnc2Oc2ccc3c(ccn3C(=O)Nc3cccc(C(F)(F)F)c3)c2)C1 +O=C(NC(=O)c1c(F)cccc1Cl)Nc1cc(N2C(=O)C3=C(CCCC3)C2=O)c(F)cc1Cl +N#Cc1c[nH]c(C(=O)Nc2ccc(-c3ccc(N)cc3)cc2C2=CCCCC2)n1 +CC1C(c2ccccc2)C1(NS(=O)(=O)N1CCn2c(nc3ccc(F)cc32)C1)C(=O)O +C=CCCCCCCOCCCCCCOC1CC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CO1 +NCCCCC(NC1CCc2ccccc2N(CC(=O)O)C1=O)C(=O)O +Nc1nccc2ccc(OCCN3Cc4cc(-c5ccccc5S(N)(=O)=O)ccc4C3=O)cc12 +Cc1nc2cnccc2n1CCN1CCN(C(=O)c2cn(C(=O)N(C)C)c3cc(-c4ccc(F)cc4)ccc23)CC1 +COc1ccc2[nH]c(-c3cccc(O)c3)c(-c3ccncc3)c2n1 +Clc1ccc(C(c2cccnc2)N2CCN(c3ccccc3)CC2)cc1 +CSCCOc1ccc(NC(=O)c2ccc(Cl)cc2Cl)c(C(=O)O)c1 +CN1C(=O)N(Cc2cc(F)ccc2F)C(=O)C12C(=O)N(CC(=O)O)c1ccc(Cl)cc12 +COc1cc2ncnc(N3CCN(C(=O)Nc4ccc([N+](=O)[O-])cc4)CC3)c2cc1OC +O=C1NC(=O)c2cc3c(Cl)c(-c4ccccc4)[nH]c3cc21 +Cc1cccnc1-c1cc(N2CCC3(CC2)CN(C)C(=O)O3)ncc1Cl +C[n+]1c(-c2ccccc2)nn(CC(=O)CCc2ccccc2)c1-c1ccccc1 +Cc1cc2c(C)ccc(-n3c(C)nnc3SCC(=O)Nc3ccccc3Br)c2cc1C +O=C(NO)c1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c2ccco2)cc1 +Cc1ccc(C)c(Cn2cc(CC(C)Nc3ncnc4c3ncn4C3OC(C(=O)NC4CC4)C(O)C3O)c3ccccc32)c1 +O=C1C(N2CCC(c3ccc(O)cc3)C(F)C2)CCN1Cc1ccc(Cl)c(Cl)c1 +O=c1[nH]c2cc(-c3ccc(F)cc3)ccc2cc1O +COCCn1c(SC)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(=O)CC(F)(F)F)c1 +NS(=O)(=O)Oc1ccc2nc(C=C3C4CC5CC(C4)CC3C5)oc2c1 +CN1CC(c2cccnc2Oc2ccc(C(=O)c3nc4ccccc4[nH]3)cc2)CC1=O +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(NS(=O)(=O)N4CCC4)ccc3N2)c(O)c2cccnc21 +CC(=O)Nc1cccc(Cn2c(C(=O)O)c(-c3ccccc3F)c3cc(Cl)ccc32)c1 +CC(C)(CO)NC(=O)c1nn(-c2cc(F)ccc2F)c2c1CC1CC21 +O=C(Nc1nocc1Cl)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +Cc1cccc(Cl)c1Nc1nc2cc(C(=O)NC3CCC(C(F)(F)F)CC3)c3c(c2[nH]1)OCCO3 +Cc1cn(-c2ccc(Nc3nc4c(s3)CCCC4c3ccccc3)cc2C(F)(F)F)cn1 +O=C1Nc2ccc(C(=O)O)cc2C1=NNc1ccccc1C(=O)O +COc1cc2c(cc1OC)C1(O)C(=O)c3ccc4c(c3OC1CO2)C=CC(C)(C)O4 +CN1C(=O)C(NC(=O)c2ccc(Cl)cc2)N=C(c2ccccc2F)c2ccccc21 +Cc1noc(-c2cnn3c2n[n+]([O-])c2ccc(OCc4ccccc4)cc23)n1 +CC(C)(C(N)C(=O)N1CC(F)CC1C#N)S(=O)(=O)Cc1csc2ccc(Cl)cc12 +CN(C)c1ncc(-c2cccc(OCC(O)CN3CCc4ccccc4C3)c2)cn1 +COc1ccc(C(=O)C=Cc2ccc(O)c(O)c2)c(O)c1 +CC12CCC3c4ccc(O)c(F)c4CCC3C1CCC2(O)Cc1ccccc1 +CCc1cc(C(C)=O)c(O)cc1OCc1cccc(C(=O)Nc2nc(CC(=O)NO)cs2)n1 +CN(CCO)c1ccc(C(=O)Nc2sc(Nc3ccc4ccccc4c3)nc2C(N)=O)cc1 +COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1N(C)CCCN(C)C +N#Cc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 +NC(=O)c1sc(-c2ccnc(N)n2)nc1-c1ccc(Cl)cc1Cl +C=CC(=O)Nc1cccc(N2C(=O)N(C)Cc3cnc(Nc4ccc(N5CCCCC5)cc4OC)nc32)c1 +CCC(CC)C(c1ccc(Nc2nc3ccccc3s2)cc1)n1cncn1 +CC(C)(C)NCC(=O)N1CCCC1C(=O)c1noc(-c2ccc(F)cc2)n1 +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCCC(O)CC2)C1 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+O=C(Nc1ccc([N+](=O)[O-])cn1)C1CC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C(O5)C1=O +Nc1nccn2c(C3CCC(CO)CC3)nc(-c3cc4ccccc4[nH]3)c12 +Cc1cc(C(=O)N2CCC3(CC2)CN(C(=O)OCC(C)(C)C)C3)cc2cn[nH]c12 +COCCN1CCC(NC(=O)c2ccc(Nc3ncc4c(n3)-c3c(nn(C)c3-c3ccccc3C)CC4)c(Cl)c2)CC1 +CN(C)CCn1c(=O)c2ccc(NCCN)c3c(=O)c4ccccc4n(c1=O)c23 +COCCCN1CCN(C(=O)c2cc3c(cc2C)[nH]c(=O)c2cnn(CC4CC4)c23)CC1C +CC(Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O)C(C)(C)C +COC(=O)C1=C(CN2CCOCC2C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1C +COc1cc(-c2ccc3ncc(C(C)=O)c(NC4CCC(N)CC4)c3c2)cc(Cl)c1O +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)O)cc3)[nH]c2n(CCc2ccc(N)c(I)c2)c1=O +O=C(c1ccc2c(c1)CCNC2)N1CCN(S(=O)(=O)c2ccc3cc(Cl)ccc3c2)CC1 +CC(CSc1ccc(-c2ccccc2)cc1)(C(=O)NO)S(C)(=O)=O +CCCCCCCCC=CCCCCCCCCNC(=O)Nc1c(C(C)C)cccc1C(C)C +CN1CCN(CCCC=Cc2ccc3c(Nc4ccc(Sc5nccn5C)c(Cl)c4)c(C#N)cnc3c2)CC1 +COc1cc(C2=C(c3c[nH]c4cnccc34)C(=O)NC2=O)cc(OC)c1OC +O=C(COc1ccc(C(=O)c2ccccc2)cc1)Nc1cccnc1 +Cc1nnc2n1-c1sc(C#Cc3ccc4c(c3)CCO4)cc1C(c1ccccc1Cl)=NC2 +CCN(C)C(=O)c1ncncc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +O=C(NCC1CCCCC1)c1cccc(C(O)(c2ccc(Cl)cc2)c2cccnc2)c1 +CCC1(c2cccc(COc3ccccc3)c2)Oc2ccccc2-n2cccc2C1=O +COc1ccc(S(=O)(=O)N(Cc2ccccc2)C(C)C(=O)NO)cc1 +O=C(Nc1ccc(C2CCNC2)cc1)c1ccc(Br)cn1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)cc2c(=O)n(CC(N)=O)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +NS(=O)(=O)c1ccc(NC(=O)CN(CCN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)CC(=O)O)c(Br)c1 +COc1cc(C(=O)n2ccc3cc(C)ccc32)cc(OC)c1OC +CCCCS(=O)(=O)N(Cc1ccccc1)c1ccc2ncn(Cc3ccc(-c4ccccc4-c4nnnn4C)cc3)c(=O)c2c1 +CCC(C(=O)Nc1ccc(C(=O)O)cc1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O +CCC(C)(C)NCC(O)c1cc(OC(=O)N(C)C)cc(OC(=O)N(C)C)c1 +COc1cc(Sc2c(-c3ccccc3)[nH]c3cc(F)ccc23)cc(OC)c1OC +O=C1NC(=O)C(Cc2ccc(Oc3ccc(Cl)cc3Cl)cc2)S1 +Cc1sc2c(c1C)C(N1CCN(C)CC1)=Nc1cc(F)ccc1N2 +Cn1nc(-c2cnccc2C(F)(F)F)c2ncc(OCc3ccccn3)nc21 +CC(NP(=O)(Nc1ccn(C2CSC(CO)O2)c(=O)n1)NC(C)C(=O)OCc1ccccc1)C(=O)OCc1ccccc1 +COc1cccc(Sc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)noc2C)c1 +N#CC(Cc1ccc(-c2cn[nH]c2)cc1F)NC(=O)C1NC2CCC1C2 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+Nc1ncnc2c1nc(NCc1ccc(F)cc1)n2C1OC(CO)C(O)C1O +CC(=O)OC1CC(Nc2nc3c(nc2N2CCN(Cc4ccc(F)cc4F)CC2)CCN(C(C)=O)C3)C1 +COc1ccc(N(C)c2nc(Cl)nc3ccccc23)cc1OC +COc1ccc(CCNc2nc(NCCCN3CCCCC3C)ncc2C(=O)NCc2ccccc2)cc1OC +COC(=O)c1cccc(-c2nnc(C(=O)CCCCCCc3ccccc3)o2)n1 +Cc1c(Cn2ncc(N3CCNCC3)c(Cl)c2=O)cccc1NC(=O)c1ccc(-c2cccc(C(N)=O)c2)cc1 +Nc1nccc(-c2nc(C3CC3)[nH]c2-c2cc(F)cc(NS(=O)(=O)c3c(F)cccc3F)c2Cl)n1 +CC(=CCN1CCCCC1)c1ccc(-c2ccccc2)cc1 +O=S(=O)(Nc1cccc(B(O)O)c1)c1cccc(S(=O)(=O)Nc2cccc(B(O)O)c2)c1 +CC(C(N)=O)c1ccccc1CCc1nc(Nc2ccnnc2)ncc1Cl +CC1(c2nc(NC(=O)c3ncc(Cl)cc3Cl)ccc2F)N=C(N)OCC1(F)F +COC1N(C2CC(N=[N+]=[N-])C(CO)O2)C(=O)NC(=O)C1(C)Br +COc1ccc(Sc2ccc(Cl)cc2N2CCN(CC(=O)O)C(C)C2)cc1 +CN1C2CCCC1CC(Nc1nc(-c3ccc(Oc4ccc(F)cc4)cc3)c3ccccc3n1)C2 +O=C1c2ccccc2CCCN1CCCN1CCN(c2cccc(Cl)c2Cl)CC1 +CCCC#CCOc1nc2oc(=O)cc(CC)c2c(=O)[nH]1 +Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC2(CCOCC2)c2nc(Cl)c(N3CCOCC3)cc21 +O=C(O)C1=Cc2c(ccc(Cl)c2Oc2ccccc2)OC1C(F)(F)F +O=C(NCCN1CCOCC1)c1ccc(Nc2nccc(Nc3ccccc3Cl)n2)cc1 +CN1C(=O)C(c2ccncc2)(c2cccc(-c3cnccn3)c2)N=C1N +Cc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3ccc([N+](=O)[O-])cc3)CC2)c(C)c1 +C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(OCc4ccccn4)c(Cl)c3)ncnc2cc1OCCOC +CN(C)CC1CCc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc2C1 +O=C(O)Cn1cc(Cc2nc3c(F)c(F)cc(F)c3s2)c2cccc(F)c21 +CC(=O)Nc1ccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2F)cc1 +Cc1cc2c(ccc3c(=O)cc(-c4ccccc4)oc32)o1 +COC(=O)C(c1cccc(C)c1C)N1CCC(CCN2C3CCC2CC(n2c(C)nc4ccccc42)C3)(c2ccccc2)CC1 +CC(C)(O)C1CCN(Cc2cc3nc(-c4c(F)ccc5[nH]ccc45)nc(N4CCOCC4)c3s2)CC1 +Cc1ccc(-n2nccn2)cc1CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1ccc(F)c(NS(N)(=O)=O)c1 +Cc1c(-c2ccc(-c3ccc(C(F)(F)F)cc3)nc2)[nH]c2ccccc2c1=O +CCCN(CC1CC1)c1cc(C)nc2c(-c3ccc(OC)cc3OC)c(C)nn12 +O=S(=O)(Nc1ccc2c(c1)C(C1CCNC1)=CC2)c1c(Cl)nc2sccn12 +CCCC(C)(C)C(=O)NCc1ccc2c(cnn2-c2ccc(F)cc2)c1 +CC(C)(C)c1ccc(C(=O)CC(=O)c2cc(Cl)ccc2O)cc1 +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N3CCCCCC3)nc2c1 +NC(=O)c1sc2nc(-c3cccc(F)c3)ccc2c1N +CC12CCC(O)CC1CCC1C2CCC23CC=CC(=O)C2CCC13 +COc1cc(C(=O)NS(=O)(=O)c2ccccc2)ccc1Cn1cc(Cl)c2ccc(NC(=O)OC3CCCC3)cc21 +Cc1cc(-c2cc(Cl)cnc2Oc2ccc(C(=O)c3nc4ccccc4n3C)cc2)ccn1 +O=C(NC1N=C(c2ccccc2F)c2ccccc2-n2cnnc21)OCc1ccccc1 +COc1ncc(-c2ccc3nc(NC(=O)NCCN4CCOCC4)sc3c2)cc1NS(=O)(=O)c1ccc(F)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CN(C)CC4c4ccc(F)nc4)ncc23)ccn1 +COc1cc2c(N)nc(N3C(C)CN(C(=O)CC(NC(C)C)c4ccc(C#N)cc4)CC3C)nc2c(F)c1OC +CN1CCN(CCN(C)C(=O)c2cc3cc(Nc4nccc(-c5cn(C)cn5)n4)cc(Cl)c3[nH]2)CC1 +NC(=O)CC(Nc1cccc(O)c1)C(=O)Nc1nc2ccc3[nH]ncc3c2s1 +CCOc1nccc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c1OC +COc1cc(-c2cn(C3CCc4ccccc4N(C)C3=O)nn2)ccc1-n1cnc(C)c1 +CC(=O)Nc1ccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)cc1 +CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1Nc1nnc(-c3cnccn3)s1)c1c(O)ccc(Cl)c12 +CCC(CCS(C)(=O)=O)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +O=C(O)c1cncc(-c2noc(C3CCCCN3C(=O)COc3ccccc3)n2)c1 +CC(c1ccc(-c2ccccc2)cc1)C(NC(=O)C(C)(C)N)C(=O)NC(c1ccc(Cl)cc1)C(F)F +CC(C)n1nc(-c2ccccn2)cc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1 +CN1CC2CC1CC2OC(=O)C(C)(c1ccccc1)c1ccccc1 +COc1cc(-c2ncn(C)c2-c2ccc3c(c2)c(Cl)cn3C)cc(I)c1OC +Cc1cc(N2CC3CCN(C(=O)c4ccc(C)nc4-n4ccnn4)CC32)nc(C(F)(F)F)n1 +CC(C)c1cccc(C=CC2C3CCCCC3CC3C(=O)OC(C)C32)n1 +Cc1cc(SCc2ccc(OCc3ccc(C(F)(F)F)cc3)cc2)c2c(c1OCC(=O)O)CCC2 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4nccnn4)ccn23)c1 +O=C(O)c1ccc(-c2c(CCc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cc1O +CCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)cn1 +CN(C)CCn1c2c3c(n[nH]c(=O)c4cccc1c34)CN(C(=O)C1CC1)C2 +Nc1nc(NCc2cccc(O)c2)nc2sc(-c3ccco3)nc12 +CC(C)(CNS(C)(=O)=O)c1nc(-c2ccc(Cl)c(O)c2)c(-c2ccncc2)[nH]1 +C=Cc1c(N)ncnc1N1CCN(C(CN)c2ccc(C(F)(F)F)cc2)CC1 +CCSCC1CC(O)(c2ccccc2)CC(c2ccccc2)O1 +COc1ccc2c(c1)C(CCNC(C)=O)CC(c1cccc(NC(C)=O)c1)C2 +OCC1OC(n2cnc3c(CSc4ccc(Br)cc4)ncnc32)C(O)C1O +N#Cc1ccccc1-c1ccc(CSc2nnc(-c3ccncc3)o2)cc1 +O=C1CCC(CCNCc2ccc(Cl)cc2)N1CC1(N2CCCCC2)CCCC1 +CCN(CC)CCn1nc2c3ccc(O)cc3sc3c(NCCN)ccc1c32 +CCCn1nc(CC)c(C(=O)O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(NC(=O)C(F)F)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 +Nc1ccc2c(c1)oc1c(N3CCNCC3)c(F)cc3c(=O)c(C(=O)O)cn2c13 +CC(OC1CCN(C)C(=O)CC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnc2ccc(F)cn12 +Cc1ccc(C(=O)Nc2cc(N(C)CCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCCCC3)nc12 +CCc1nc2cc3c(cc2o1)CCN(CCCSc1nnc(-c2ccc(C(F)(F)F)cc2)n1C)CC3 +COc1cccc(Nc2nc(-c3cccc4onc(C)c34)nc3c2cnn3C)c1 +N#Cc1ccc(NC(=O)N2CCC(O)c3ccc(C=O)nc32)nc1 +CN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4nnc5ccc(-c6ccc(F)cc6)nn45)c3n2)CC1 +O=C(NCc1ccc(Cc2c[nH]cn2)cc1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC1(C)Cc2c(N3CCOCC3)nc3sc4c(NCCN5CCOCC5)ncnc4c3c2C1 +CC1=C([N+](=O)[O-])C(c2ccccc2)C2=C(O)c3ccccc3C2=N1 +Cc1ccc(-c2cc(F)ccc2OCc2ccc(F)cc2)n1-c1cc(C(=O)O)c2ccccc2c1 +CCCC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 +CC(C(=O)O)c1ccc(-c2cccc(OC(=O)NCC3CCCCC3)c2)c(F)c1 +CCN(c1nc(C)cc(-c2ccccc2Br)n1)c1ccc(C(C)C)cc1Br +CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)CC3CCCCC3)C2)nc1C +CC(OCc1cc(F)cc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccc(F)cc2)c1)C(F)(F)F +Cc1ccc(-c2cc(C(=O)NC(C)c3cnccn3)cc(-n3c(=O)oc4ccccc43)c2)nc1 +O=C(CCc1ccccc1)N(Cc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +N#Cc1ccccc1Cn1c(N2CCCC(N)C2)nc(-c2ccccc2)cc1=O +Cc1nc(C(CC2CC2)N(C)C(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)no1 +NC1CCCN(c2cccc(-c3n[nH]c4cnc(-c5cncc(F)c5)cc34)n2)C1 +COc1ccc2c(c1)-c1nc(-c3ccc(C4(N)CC(C)(O)C4)cc3)c(-c3ccccc3)n1CO2 +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1OC1COCCC12 +CCOC(=O)c1cc(C#N)c(N2CC(C(=O)NS(=O)(=O)c3ccc(Cl)s3)C2)nc1C +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc(-c2ncccc2C(F)(F)F)nc1O +COC(=O)c1cccc(-c2cnc(C(=O)C3CCc4cc(OCc5ccccc5)ccc4C3)o2)n1 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2ccc3c(c2)OCO3)cc1 +COCCNC(=O)c1ccc(Nc2ncc(C(F)(F)F)c(Oc3cccc4c3C(=O)N(C)C4)n2)c(C)c1 +Cc1n[nH]c(O)c1C(c1ccc(N(C)C)c(Br)c1)c1c(C)n[nH]c1O +CN(C)c1ccc(C(=O)NCC=CCN2CCN(c3ccccc3OCCF)CC2)cc1 +CC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 +Fc1ccc2sc3c(c2c1)CCN(Cc1cncc2ccccc12)C3 +Cc1cnc(NC(=O)C(COC(C)CO)Oc2ncnc3c2cnn3-c2c(Cl)cccc2C#N)cn1 +CCN(CC)CCCn1ccc2ccc(NC(=N)c3cccs3)cc21 +COc1cn(C)c(=O)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(C)nn1C)C2=O +Cc1ccc(Cc2cc(C3SC(CO)C(O)C(O)C3O)ccc2Cl)cc1 +Cc1cc(C)cc(-c2[nH]c3ccc(C(C)(C)C(=O)N4CCCC4)cc3c2CCNCCCCc2cccnc2)c1 +Cc1cc(C(=O)N2c3cccc(O)c3NC3=C(C(=O)CC(C)(C)C3)C2c2ccc(OCc3ccccc3)cc2F)no1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(NC3CCCCC3N(C)S(C)(=O)=O)n1)C(C)(C)CN2 +O=C(C=Cc1ccc2c(c1)OC(C(=O)O)C(c1ccc(O)c(O)c1)O2)OC=Cc1ccc(O)c(O)c1 +CC(C)(C)c1ccc(C(=O)NCCOc2ccccc2F)cc1 +CCC(C)C(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccc(OC(C)C)cc2)cc1 +Cc1nc(-c2cccc(C(=O)Nc3cccc(CNc4ncnc5c(C(N)=O)cccc45)c3)c2)no1 +CNC1CCC(c2ccc(Cl)c(Cl)c2)c2ccc(CNS(C)(=O)=O)cc21 +CC1=CC(=O)C(O)C2(C)C1CC1OC(=O)C(OC(=O)C(C)CO)C3C(C)C(O)C4(O)OCC13C42 +COc1ccc(C(=O)CNC(=O)CCn2c3c(c(=O)[nH]c2=O)CCCC3)cc1 +O=S(=O)(NC1C2CCN(CC2)C1Cc1cccnc1)c1ccccc1 +OC1(c2ccc(F)cc2)CCN(Cc2c[nH]c3ccccc23)CC1 +COc1ccc(Cl)cc1N1CCN(CCn2c(=O)[nH]c3c([nH]c4ccccc43)c2=O)CC1 +Cc1nc(-c2cn3c(n2)-c2cnc(-c4cnn(C)c4C4CCCN(C(C)C)C4)cc2OCC3)n(C(C)C)n1 +N=C(N)N1CCC(C(=O)NCC(=O)N2CCN(CC(=O)O)C(=O)C2CC(=O)O)CC1 +O=C(Nc1ccc(S(=O)(=O)O)cc1)C(CS)Cc1ccc(-c2ccccc2)cc1 +COCCN(C)c1nc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(C(N)=O)cc3)CC2)nc2ccsc12 +CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(C2=C(c3nn[nH]n3)CCC2)cc1 +CC1=C(C(=O)OC(C)C)C(c2ccccc2Cl)C(C(=O)O)=C(C(=O)O)N1Cc1ccc(Cl)cc1 +CC(Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)c1ccc(C#N)cc1F)CC2)c1ccc(C(F)(F)F)cc1 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCOCC4)cc3)cc12 +CCN(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)c1ccccc1C(F)(F)F +COc1ccc(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(N4CCN(C)CC4)c(F)c3)n2)c(OC)c1 +CCc1ccc(S(=O)(=O)N2CCCC(O)(c3ccccc3)CC2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)OC3CCOCC3)c2cn1)c1ccc(F)cc1 +COc1ccccc1N1CCN(CCn2nc(-n3ccc4ccccc43)ccc2=O)CC1 +Cc1ccc(-n2cc3c(n2)c(=O)[nH]c2ccccc23)cc1 +CN1CCC=C(c2nsnc2OCCCCCCCC2CCN(CCCN3C(=O)CCc4ccccc43)CC2)C1 +COc1ccc(C=C2CS(=O)(=O)CC(=Cc3ccc(OC)c(OC)c3)C2=O)cc1OC +Cc1ccc(NC(=O)C2CSc3c(C4CC4)c(Cc4cccc(C)c4C)c(N)c(=O)n32)cc1 +COc1ccc(CCn2c(=O)c3ccccc3c3nc4ccc(NCCCn5ccnc5)cn4c32)cc1 +CCCCc1nn(CCCCCC(=O)OCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN1CCN(c2ccc(NC(=O)c3cc(-c4ccc5c(c4)OCO5)cnc3O)cc2)CC1 +O=C(O)CC(Cc1ccccc1)NC(=O)C(CC(=O)NO)Cc1ccccc1 +Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)(F)F)cc2)s1 +Cc1cc(NCC(N)c2ccccn2)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +Nc1ncc(C(=O)N2CCOCC2)cc1-c1ccc(C(=O)NC(CO)c2cc(F)cc(Br)c2)c(F)c1 +CC(C)(C)NC(=O)c1cccc(-c2cc3nccc(-c4ccc(OC(F)F)c(OCC5CC5)c4)n3n2)c1 +CC(C)CC(C)NC(=O)CNC(=O)C(COC(C)(C)C)NC(=O)C(N)Cc1ccc(O)cc1 +COCCOc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OCCOC +CCN(CC)c1ncc(N(CC)C(=O)Nc2ccccc2)c(NC(Cc2ccc(OC(=O)N3CCCC3)cc2)C(=O)O)n1 +COc1ccc2ccc(S(=O)(=O)N(CC(=O)O)C3CCN(Cc4cccc(C(=N)N)c4)C3=O)cc2c1 +O=c1oc2ccc(Cl)cc2c2nc(-c3c(F)cccc3F)nn12 +Cc1ccccc1Nc1ncnn2ccc(CN3CCC(N)CC3)c12 +N=C1NC(c2ccccc2Br)CC2CCC(CCc3ccccc3)N12 +CC(=NNc1nc(-c2ccccc2)c(C)s1)c1ccccn1 +O=C(NC1CCCC1)NC(Cc1ccccc1)(c1cc(F)cc(C(F)(F)F)c1)c1ccc(Cl)cn1 +COc1ccc(C(=O)NC(=O)Nc2ccc3c(c2)NC(=O)C3=Cc2ccc(O)cc2)cc1 +CC(C)CC(NC(=O)Cc1ccccc1)C(=O)NC(CC1CCCCC1)C(O)C(=O)c1ccccc1 +CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCCC(F)(F)C4)cc3c2)CC1 +Cc1ccc(CNCC2CC3(c4ccccc4)CCN2C3)cc1 +Cn1cc(-c2nc(-c3cn(C)c4ncccc34)cs2)c2ccccc21 +FC(F)(F)Oc1ccc(Nc2cc(Nc3nccn3-c3cc(Br)cc(C(F)(F)F)c3)ncn2)cc1 +COc1cc2oc(-c3cccc(OCCCCN4CCN(C)CC4)c3)cc(=O)c2c(OC)c1OC +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)NC1CCN(C(=O)Oc2ccccc2)CC1 +CCOCCC1(Oc2ccc(Oc3cccc(F)c3)cc2)C(=O)NC(=O)NC1=O +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1c(F)cccc1F)C(C)C +COc1cc(C2c3cc4c(cc3C(OC(=O)c3cnc5ccccc5n3)C3COC(=O)C23)OCO4)cc(OC)c1OC +O=S(=O)(c1cccc(F)c1)c1cc(F)c2c(c1)CCCC2CNCCO +COc1cc(-c2nc(-c3cc(C)nc(C(F)F)c3)c3n2CC(CF)OCC3)ccc1Cl +CC1(C)C(=O)NC(=O)c2c1ccc1[nH]c(Nc3c(Cl)cccc3Cl)nc21 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)Cn1ccnc1)C2 +Cc1cc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NC2CCN(C)CC2(C)C)c(C)cc1Cl +COc1ccc(OC)c2c1c(OC)cc1c(=O)cc(-c3ccc(O)cc3)oc12 +O=C(Nc1ccc(C(=O)CCl)cc1)Nc1ccc(-c2nc(N3CCOCC3)c3cccnc3n2)cc1 +CN1CCN(c2nc(Nc3ccccc3)nc(Nc3cccc(Nc4ccnc5cc(Cl)ccc45)c3)n2)CC1 +CCOc1ncccc1C1C(C(=O)C2CCCC2)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +CC1(n2c(-c3cccnc3)nc3ccc(F)cc32)CC1 +C=CCOC(=O)N1CCCC(C(=O)N2CCN(C(=O)CCc3nc4ccccc4c(=O)[nH]3)CC2)C1 +CCCCN(CCCC)C(=O)C1OC(C(=O)O)=CC(N)C1NC(C)=O +CN(CCO)c1ccc(-c2nc3c(C(=O)NC4CCCNC4)ccnc3[nH]2)s1 +Cc1c(C(=O)NCCCCCCCCNCc2ccccc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +NC(=O)c1ccc(-n2c3c(c4ccccc42)C(=O)CCC3)cc1NC1CCC(O)CC1 +CSc1ccccc1C=CS(=O)(=O)Nc1ccccc1S(N)(=O)=O +Fc1ccc(OCCN2CCC(c3ccc(F)cc3)CC2)cc1 +CS(=O)(=O)c1ccc2c(c1)CCN2c1ncnc2c(C3CCN(c4ncc(F)cn4)CC3)coc12 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3C(F)(F)F)nc12)N1CCC(O)C1 +C#CCN(C)CC(=C)c1cccc(OCc2cccc(OC)c2)c1 +Cc1ccccc1N1CCN(CCCCNC(=O)c2ccc3ccccc3c2)CC1 +O=C(O)CN(C1(c2ccc(-c3ccccc3OC(F)(F)F)cc2)CCC1)S(=O)(=O)c1ccc(OC(F)F)cc1 +Cc1nnc2sc(C(=O)NC3CN(c4ccc(S(=O)(=O)C(F)(F)F)cc4)C3)c(N)c2c1C 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+O=C(C=Cc1ccc2c(c1)CN(Cc1ccccc1)C2=O)NO +O=C(C=Cc1ccccc1)Nc1nc(-c2ccncc2)cs1 +COC(=O)CNc1nc(-c2ccccc2F)nc2ccccc12 +CCc1cc(-c2ccc(C(N)=O)c(NC(C)(C)C)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c2n1 +Nc1ccn(C2OC(COP(=O)(O)OC(C(=O)Nc3ccccc3)P(=O)(O)O)C(O)C2O)c(=O)n1 +COc1cc(-c2csc3ccccc23)cc2c1OCCN(Cc1cccnc1OC)C2 +O=C1c2ccc(NC3=NCCN3)cc2C(=O)c2ccc(NC3=NCCN3)cc21 +CCCN1CCOc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc21 +COc1ccc(-c2cc3ccccc3nc2C=CC(=O)c2ccsc2)cc1 +CCCNC(=S)Nc1cc(C=CC(=O)NO)ccc1OCCN(CC)CC +Oc1ccc(C23CCC(C2)N(CCc2ccccc2)CC3)cc1 +NC(=O)c1ccc2c(c1)CCOC2CCN1CC=C(c2noc3cc(F)ccc23)CC1 +CC(C)N(C)c1cc(-c2csc(N(C)C(=O)c3ccc(F)cc3)n2)ncn1 +Nc1ccc(S(=O)(=O)N2CCc3cc(O)ccc3C2C(=O)NO)cc1 +O=C(NCC(=O)N1CCC(NC2CCC(O)(c3ccc(-c4cnccn4)cn3)CC2)C1)c1cccc(C(F)(F)F)c1 +COc1ccncc1N1C(=O)c2c(Cl)ccc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2C1=O +CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)n5cccn5)c4)c(C)nc23)ccn1 +CC(C)(C)C1CCN(c2cccc(Nc3cc(-c4cccc(C(N)=O)c4)nn4ccnc34)n2)C1 +O=C(C=Cc1cccn(CCCc2cccc(Cl)c2)c1=O)NO +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2cc(C)nc(NCC(C)(C)C)c2n1 +Cc1cc(C)[n+](CC(=O)Oc2ccc3nc(S(N)(=O)=O)sc3c2)c(C)c1 +COC(=O)CNC(=O)C1CC(NC(=O)c2cc(C3CC3)nn2C)CN1C(=O)c1coc2ccccc12 +CCc1cc(CNc2cc(Cl)nn3c(-c4ccc(OC)c(S(=O)(=O)NCCN(C)C)c4)c(C)nc23)ccn1 +CNC(=O)Oc1cccc(CN(C)CCCCCCCCOc2ccc3c(=O)c4ccccc4oc3c2)c1 +CC(C)OC(=O)c1cccc(NC(=O)N(CCC(c2ccccc2)c2ccccc2)CCN2CCOCC2)c1 +CCCCc1nn(-c2cc(Cl)ccc2Cl)c(C(=O)O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCN(c3ccc(C#N)cc3)CC2)c2ccc(C)c(Cl)c2)CC1 +CCC1CC(CC)c2cc3c(C(F)(F)F)cc(=O)oc3cc2N1 +COc1ccc(Cn2c(=O)c(NCCN3CCOCC3)nc3ccc(-c4ccc(F)c(F)c4)nc32)cc1 +CNC(=O)C(Cc1ccccc1)NC(=O)c1c(C)n(CCN2CCOCC2)c2c(OC)cccc12 +CN(C)C(=O)c1ccc(Nc2nc3cccc(-c4ccc(C(=O)N5CCOCC5)cc4)c3o2)cc1 +COc1ccc(CN(C(CC(C)C)C(N)=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1ccnc(N2CCOC(CO)C2)c1 +Cc1c(C(=O)Nc2ccnc(Cl)n2)nn(C)c1-c1ccc(F)cc1 +CNCCNC(=O)C1C(C(=O)NCc2nc(C(C)=O)cs2)C2C=CC1C21CC1 +NC(=O)c1ccc2[nH]c(-c3ccc(Cc4ccc5ccccc5c4)cc3)nc2c1 +CC(C)CC(NC(c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(F)(F)F)C(=O)NC(C)(C)C#N +CC(Oc1cc(-c2nc(-c3ccc(CN(C)C)cc3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F +O=C(NCC1(O)CCCCCC1)c1cc(-c2ccccn2)ccc1Cl +Nc1cccc(C(=O)NN=C2c3cc(Cl)ccc3C(=O)C3C=CC=CC23)c1 +C=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2n1 +CC(C)(O)COc1ccc2c(c1)c(NC(=O)N1C(C(=O)NCc3cccc(Cl)c3F)CC3CC31)cn2C(N)=O +CC(C)n1nc(Cc2cc(F)cc(F)c2)c2c(N)ncnc21 +COc1cc(CN=C(S)NCCc2ccc(Cl)cc2)ccc1OCCN +Cc1[nH]c2ccccc2c1C=NNc1nc(Nc2ccccc2)nc(N2CCOCC2)n1 +CCCCc1ccc(C2=NN(S(=O)(=O)c3ccc(CCCC)cc3)CCC2)cc1 +COCC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cn3)c2)c2cncnc21 +Cc1ccc(C2C3=C(CC(C)(C)CC3=O)Nc3nc4c(c(N)c32)CCCC4)cc1 +CC1(CCC(=O)NC(Cn2cncn2)CP(=O)(O)O)SCCS1 +COCC1CCCN1c1cc(Nc2nccs2)nc(-n2nc(C)cc2C)n1 +CCCN(CCCCOc1ccc2ccnn2c1)C1CCc2c(O)cccc2C1 +Nc1ncnc(N2CCC(c3nc(-c4ccc(F)c(C(F)(F)F)c4)cn3CCN3CCCCC3)CC2)c1-c1cccc(F)c1 +COc1cccc2c1ncc1c(=O)n(C(C)C)c(=O)n(C3CCCC3)c12 +CC(C)S(=O)(=O)c1c(O)n(Cc2ccc(F)c(F)c2)c(=O)c2ccc(Cl)cc12 +C=C(c1ccccc1)c1ccc2cccc(-c3cc4c([nH]3)CCNC4=O)c2n1 +COc1ccc(CNc2nnc(N3CCC(=O)CC3)c3ccc(C#N)cc23)cc1Cl +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(NCC(C)(C)O)c2n1 +CN(C)CCNC(=O)c1cc(Cl)cc2nc3ccccc3nc12 +CCC(c1ccncc1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +O=C(CCc1cn(Cc2ccccc2)c2ccc(F)cc12)Nc1ccncc1 +COC(=O)c1cc(-c2ccc(C=C3SC(=O)N(CCC(=O)O)C3=O)s2)ccc1O +COc1cc2cc[n+](C)c(Cc3cccc(Cc4c5c(OC)c(OC)c(OC)cc5cc[n+]4C)c3)c2c(OC)c1OC +CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1Br +CC(C)n1cnc2c(Nc3cccc(-c4ncccn4)c3)nc(Cl)nc21 +CSc1nn2cc(-c3cc4c(OCc5ccc(F)cc5)cccc4o3)nc2s1 +CCC(C)C(NS(=O)(=O)c1ccc(Br)c(Br)c1)C(=O)NC(Cc1cscn1)C(=O)NO +CC(c1ccn(-c2ccc(C(F)(F)F)cc2)c1)N1CCC(NC(=O)COc2cccc(Cl)c2)CC1 +CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1cccc(Cl)c1 +CCCCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 +COc1ccc(CC(C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O +CC(C)(O)C1CCC(Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1 +NC(=O)c1cc(-c2ccnc(N)n2)[nH]c1-c1ccccc1Cl +COc1cc(S(=O)(=O)c2ccccc2F)cc2c3c(n(C)c12)CC1CCC3N1 +O=C(Nc1cc(F)ccc1B(O)O)c1ccc(Oc2ccc(C(F)(F)F)cc2)nc1 +CCC(C)C(NS(=O)(=O)c1cc(Br)c(Br)s1)C(=O)NC(CNC(=O)OCc1ccccc1)C(=O)NO +O=C(O)c1cn2c3c(nc(O)c2n1)-c1ccccc1C3 +CN(C)c1ccc(C(=O)C=Cc2ccc(O)c(O)c2)cc1 +N#Cc1ccc(C(=O)Nc2ccc(C3CCNC3)cc2)cc1 +COc1ccc2c(CC3NC(=O)C4CCCN4C3=O)c(CC=C(C)C)[nH]c2c1 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(C4(O)CCOC4)ccc3Cl)nnc12 +CC1CN(CC(=O)N2CC(C)(C)c3ncc(Cc4ccc(F)cc4F)cc32)C(CN2CCOC2=O)CN1 +N=C(N)NCCCCC1CC(C(=O)NCC(NS(=O)(=O)c2cc(Cl)sc2Cl)C(=O)O)=NO1 +Nc1nc(Cc2ccc(Br)cc2)cc(C2CCN(C(=O)c3ccc4c(c3)OCO4)CC2)n1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1OCC(C)(CN)CO1 +CC(C)C(CC(=O)NCCn1c(-c2cccnc2)nc2ccccc21)C(=O)NC(C=O)CC(=O)O +Cc1sc(NC(=O)c2cnc(N3CCC(C(=O)O)CC3)c(Cl)c2)nc1-c1ccc(F)c(C(F)(F)F)c1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cncc(N2CCOCC2)n1 +Cc1cc(Nc2cc(C)c(C#N)c(SCCCCCCN)n2)n[nH]1 +Cc1c(COCC2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCNC(=O)OC1=C(c2ccccc2)Oc2ccccc2-n2cccc21 +CCn1cc(-c2ccnc3[nH]ccc23)c(-c2cccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c2)n1 +CCNC(=O)c1ccc(Oc2ccc(Cc3nnn[nH]3)cc2)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 +CC(C)Oc1nccc2[nH]nc(-c3cc(C(=O)N4CCCCC4)n(C(C)C)c3)c12 +CCOc1nc2ccc(C(O)(c3ccc(OC)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 +COc1ccc(NC(=O)Nc2ccc(Cl)cc2C(F)(F)F)cc1-c1c(Br)cnn1C +COc1ccc2cc3[n+](cc2c1NCc1ccccc1)CCc1cc2c(cc1-3)OCO2 +COc1ccc(-c2cnc(NC(=O)N3CCC4(CC3)OC(=O)c3ccccc34)nc2)cc1 +COc1ccccc1C=CC(=O)NC(=S)Nc1ccc(S(=O)(=O)N(Cc2ccncc2)c2ccccc2)cc1 +Cc1cccc(N2CCN(C(=O)Nc3ccc(O)cc3)CC2)c1 +CCOc1ccc(Cc2cc(C34OCC(Sc5ccccn5)(O3)C(O)C(O)C4O)ccc2Cl)cc1 +N#Cc1ccc(N2C(=O)C3NN=C(C(=O)c4ccc5ccccc5n4)C3C2=O)cc1 +COc1ccc(S(=O)(=O)c2n[nH]c3ccc(NC4CCNCC4)cc23)cc1 +O=C(NCCCCC(NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)O)OCc1ccccc1 +CC(C)C(CO)NCc1nc(-c2cc(C(F)(F)F)ccc2F)ccc1F +Cc1ccc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCN(C)CC3)nc12 +Cc1cccc(N2CCN(CCCNC(=NC#N)c3ccncc3)CC2)c1C +CN(c1ncnc2c(-c3ccc(S(C)(=O)=O)cc3)csc12)C1CCN(C(=O)C2CC2)CC1 +Cc1cc(N(C)C)nc2ccc(NC(=O)COc3ccc(C(F)(F)F)cc3)cc12 +Cc1ccc(C(=O)c2cc(Cl)ccc2NS(=O)(=O)c2ccc(S(C)(=O)=O)cc2)c[n+]1[O-] +CCN(Cc1cc(S(C)(=O)=O)ccc1-n1cc(CC(=O)O)c2ccc(C)nc21)C(=O)C1CC1 +Nc1nnc(-c2ccc3[nH]cc(-c4cncc(NC5CCCC5)n4)c3c2)s1 +CN1CCc2cc(F)cc3c2C1Cc1ccc(O)c(O)c1-3 +COc1ccc(-c2cc(Cl)c3c(N)ncnn23)cc1N1CCN(C(C)=O)C(C)(C)C1=O +O=C(O)C(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C1OCOC1C(=O)Nc1c(Cl)cncc1Cl +COc1cccc(-c2cc(COc3cccnc3)ccc2C(=O)NC(CCSC)C(=O)O)c1 +C=CCOC(=O)Nc1ccn(C2OC(CO)C(O)C2(F)F)c(=O)n1 +CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2Cc2csc(Br)c2)n1Cc1ccc(C(=O)OC)cc1 +O=C(NCCCCCCS)c1cc(-c2ccc(F)cc2)nn1CCO +Cc1[nH]cnc1C1CCN(c2ncncc2-c2ccc(F)c(Cl)c2)CC1 +COc1ccc(-n2nc(SC)c3ccc(N4CCNCC4)cc32)cc1 +c1cc2c3cnc(Nc4ccc(N5CCCC5)nn4)nc3n(C3CCCC3)c2cn1 +Cc1cccc(Oc2cc(F)cc(Nc3ccc(I)cc3F)c2C(N)=O)c1NS(N)(=O)=O +CN(c1c(F)cc(C#N)cc1F)C1CCN(c2ncnc3[nH]ccc23)C1 +CC1CCCC(COC(=O)NCCCn2ccnc2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCOC(=O)C(C(=O)OC1CC2C3OC3C(C1)[N+]2(C)C)c1ccccc1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(Cc1ccc3c(c1)OCCO3)CC2 +CNCc1cn(S(=O)(=O)c2cc(C)ccn2)c(-c2cccnc2F)c1F +N#Cc1cccc(C23CCC(N(CCN4CCC(O)C4)C(=O)Nc4ccc(F)c(C(F)(F)F)c4)CC2C3)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OC4CCC4)n3)C2)cc1 +NC(Cc1ccc(-c2ccccn2)cc1)C(=O)N1CCSC1 +COc1ccc(-c2c(C)nc3c(NCCNC(C)=O)cc(Cl)nn23)cc1S(=O)(=O)NCCO +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)(C)c1cccc(F)c1)CC2 +Cc1cc(F)cnc1C(=O)Nc1ccc(F)c(C2(C)N=C(N)C(C)(F)CC2(F)F)c1 +NC1=NC(c2cc(NC(=O)c3ccc(Br)cn3)ccc2F)(C(F)F)C2CC2O1 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3ccc(C(C)C)cc3)cc12 +CCS(=O)(=O)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1C(C)OC +Cc1c(CN(C)c2cccc3c2CCCC3)cnc2nc(N)nc(N)c12 +COc1cc2ncnc(Nc3cccc(Cl)c3)c2cc1B1OC(C)(C)C(C)(C)O1 +CC(C)Oc1ccc2[nH]nc(-c3ccnc(N4CCN(C)C(=O)C4)c3)c2c1 +CN1CCN(Cc2ccccc2S(=O)(=O)c2csc(S(N)(=O)=O)c2)CC1 +Cc1cccc(NC(=O)NC(C[S+]([O-])Cc2ccccc2)C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CCN1Cc2cc(-c3nnn(-c4cccnc4F)c3C)ccc2C1=O +CN1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncn2)CC1 +COc1ccc(-c2ccn(-c3ccc4c5c(n(C)c4c3)CCNC5)c(=O)c2)c(C)c1 +O=C(O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1ccc(F)cc21 +COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c(-c3ccc(OC)c(O)c3)[nH]c2c1 +COc1cc(C(=NO)c2noc(-c3ccc(C)cc3)n2)cc(OC)c1OC +Cc1cc(N2CCCN(Cc3csc(-c4ccccc4)n3)CC2)c2nccn2c1 +COc1ccc2c(c1)C=C(C1CC3CN(c4ccccc4)C(=O)C34CCCN14)CO2 +CCOc1ccc(-n2c(C)c(C(C)=O)c3cc(O)ccc32)cc1 +CCCS(=O)(=O)N1CCN(C2(CNC(=O)c3ccc(Cl)cc3Cl)CCOCC2)CC1 +CCOC(=O)CCS(=O)(=O)Cc1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)cc1 +CC12CC(CCCCOS(C)(=O)=O)C3c4ccc(O)cc4CCC3C1CCC2O +O=C(Nc1ccc(Br)cc1F)N1CCNCC1COc1cccnc1 +Cc1ccc(CN2C3CCC2CC(Oc2cccc(C(N)=O)c2)C3)cc1 +CC(C)(F)CCNc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +CCCCc1nc(C)n(Cc2occc2C(=O)O)c(=O)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(C)CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cccc(-c3ccccc3)n2)CC1 +Clc1cccc(C2C(NCc3ccccc3Cl)C3CCN2CC3)c1 +Nc1nccc(Nc2ccc3[nH]nc(-c4ccc[nH]4)c3c2)n1 +N#Cc1ccc(CSc2nnc(-c3ccc4c(c3)OCO4)o2)cc1 +COc1cc(C#Cc2nn(C3CN(C(=O)C=CCN(C)C(C)C)C3)c3ncnc(N)c23)cc(OC)c1 +O=C(O)CON=C(c1ccc(OCc2ccc3ccccc3n2)cc1)c1ccc(OCc2ccc3ccccc3n2)cc1 +CNC(=O)N1CCCC(C(C)Nc2nccc(-n3cnc4ccccc43)n2)C1 +O=c1c(-n2ccnn2)c[nH]n1-c1cc(C2CC2)ncn1 +CCCCCOc1c(O)cc(Br)c2c1CN1CCc3cc(OC)c(O)cc3C1C2 +O=C(C1CCOC1)N1CCC(CNc2nc3c(s2)CCCc2ccc(F)cc2-3)CC1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCCOc4cccc(Cl)c4)nc23)N1 +NC1=NC(c2cccc(NC(=O)c3ccc(C(F)(F)F)cn3)c2)(C(F)F)COC1 +O=C(NC1CCOC1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +Cn1ccc(-c2cc3c(-c4cccc(N5CCNCC5)n4)n[nH]c3cn2)cc1=O +Cc1cnc(Nc2cccc3c2OCO3)nc1-c1c[nH]c(C(=O)NC(CO)c2cccc(Cl)c2)c1 +COc1ccc(C(=O)Nc2ncc(-c3ccc(C(=O)O)cc3OCCc3ccccc3)s2)cc1 +Cn1ncc(C(=O)N2CCC2)c1C(=O)NCCc1nc(-c2ccccc2)nn1CC1CC1 +O=Cc1c(O)ccc2nc(-c3ccc(C(=O)NCCN4CCOCC4)cc3)[nH]c12 +Nc1nc(NCc2ccccc2-c2ccccc2)nc(-c2ccc(CC(N)C(=O)O)cc2)n1 +COc1cccc(-c2ccc(S(=O)(=O)Nc3cc(N4CC(C)NC(C)C4)ccc3OC)cc2)c1 +CC12CCC(=O)CC1CCC1C2CCC2(C)C1CCC21CCCO1 +CNS(=O)(=O)c1cccc(Oc2cccc(-c3c(C(C)C)nc4c(Cl)cccn34)c2)c1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1cc(C(F)(F)F)ccn1 +CCOc1ccc(C(C)=O)cc1CSc1nc2cc(F)ccc2n1CC(=O)O +Cc1cnn(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C)n2)c1 +CCC(C)n1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)c(-c2ccnc(C(F)(F)F)c2)c1C +CN(C)CC(C)(C)CNc1nccc(-c2c(-c3ccc(F)cc3)nc3cnccn23)n1 +CN1CCN(Cc2ccc(Nc3ncc(Cl)c(-c4ccc(F)cc4S(=O)(=O)N(C)C)n3)cc2)CC1 +C=C(C)C1CCC2(C(=O)O)CCC3(C)C(CCC4C5(C)CCC6(OCCO6)C(C)(C)C5CCC43C)C12 +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)OCC1CCCCC1)CC2 +COc1cc2c(N)nc(N3CCN(C(=O)CC(N)c4ccc(C(F)(F)F)cc4)CC3C)nc2c(F)c1OC +Clc1ccccc1Nc1cc2[nH]c(-c3cn[nH]c3)cc2cn1 +CCCNc1nccc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)c1F +COc1ccccc1N1CCN(CCCC2CCCc3c(OC)cccc32)CC1 +Cc1ccccc1-c1cc(C(OCc2cccc(C#N)c2)c2cncn2C)ccc1C#N +COc1ccc(CCO)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc(CCCO)cc2)c1 +CC(C)CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(N)CC1 +Cc1cc(-n2ncc(=O)[nH]c2=O)cc(C)c1Oc1ccc(O)c(Cc2ccc(F)cc2)c1 +COc1cc(-c2cn(C3CCC4CCCCC4N(Cc4ccccc4)C3=O)nn2)ccc1-n1cnc(C)c1 +Cc1c(OCC(=O)O)ccc(F)c1NCc1cc(-c2cccc(F)c2)ccc1F +O=C1c2ccc(C#Cc3ccccc3)cc2C(=O)N1CCc1ccccn1 +CC(CO)Nc1cc(NS(=O)(=O)C(F)(F)F)nc(SCc2ccccc2)n1 +Cc1ccc(-c2csc(NC(=O)Cc3cccc4c3c(=O)n(C)c(=O)n4C)n2)cc1 +CCN(CC)c1ccc(NC(=O)CN2C(=O)CSc3ncccc32)c(C)c1 +COc1ccc2sc(CNc3nncc(-c4cc(-c5ccn[nH]5)ccc4Cl)n3)nc2c1 +Cc1cc(-c2nnc3n2CCCCC3)c(C)n1-c1ccc([N+](=O)[O-])cc1 +COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCOCC1 +O=C(CN1CCCCC1)Nc1ccc2nc3n(c(=O)c2c1)CCc1c-3[nH]c2ccccc12 +CC(C)(C)c1nc(N2CCN(CCCCn3ccc(N4CCC4)nc3=O)CC2)cc(C(F)(F)F)n1 +COc1ccc(S(=O)(=O)N(CCn2cc(CCCF)nn2)C(C(=O)NO)C(C)C)cc1 +COc1ccc(C2c3[nH]c4ccccc4c3CC3C(=O)N(CCc4ccccn4)C(=O)N32)cc1 +Cc1ncnc(C)c1-c1ccc(Oc2nccc3[nH]ccc23)cc1F +Nc1cc(NC(=O)c2cccc(Cl)c2)cc(Oc2cccnc2)c1 +CCCNc1nccc(C2CCCN(CCc3c[nH]c4ccccc34)C2)n1 +O=C1OCC(Cc2ccccc2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc1C +O=C(O)C1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +CCOc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C)c3)cn2CCN2CCCC2)CC1 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccc(C#N)cc3)n2)CC1 +CCCC(=O)c1cnc(N2CCN(C(=O)NS(=O)(=O)c3ccc(Cl)s3)CC2)c(Cl)c1 +CCCNC1CCc2c(OS(=O)(=O)C(F)(F)F)cccc2C1C +CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3cc(=O)n(C)c(=O)n3C)c2)CC1 +C=C(C)COCn1c(C(F)c2cc(C)cc(C)c2)c(CC)c(=O)[nH]c1=O +COc1cccc2c1c(NS(=O)(=O)c1ccc(C)c(F)c1)nn2Cc1cccc(CNC(=O)C(C)(C)O)c1 +CC(C)Cc1c(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)noc1-c1ccccc1 +CC(C)NC(=O)C1=CC(C)(C)Oc2ccc([N+](=O)[O-])cc21 +CCCCCC(CC(=O)NO)C(=O)NC1CCCCN(CC(=O)OC)C1=O +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc4c(c3)c(N)nn4CCN(C)C)NC(=O)NC1=O)C2 +COc1ccc(NC(=O)Oc2cccc3ccc(C)nc23)cc1 +C=CC1OC2(CCC3=Cc4c(cnn4-c4ccc(F)cc4)CC32C)OC1C=C +CSc1nc(NCCc2ccccc2)c2cnn(CC(Cl)c3ccc(Cl)cc3)c2n1 +Cc1cccnc1-c1cc(N2CCC(C(=O)N3CCCCC3CO)CC2)ncc1Cl +CN1CCC(Oc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3n2)CC1 +CCc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +CC(c1ccc(Cl)cc1)N1Cc2cncn2C(CC(O)c2ccccc2)S1(=O)=O +CCN(CC)CCSc1nc(-c2cc(OC)c(OC)cc2Cl)c2c(C#N)c[nH]c2n1 +O=C(CCN1CCN(c2ccccc2)CC1)NN=Cc1ccc([N+](=O)[O-])o1 +COc1cccc2c1ccc1nc3cccc(C(=O)NC(CN(C)C)C(C)C)c3nc12 +O=C1C(=Cc2ccccc2F)CS(=O)(=O)CC1=Cc1ccccc1F +Cc1ccc(-c2c[nH]c(C3Cc4c([nH]c5ccccc45)C(C4CCOCC4)N3)n2)cc1 +CCCc1cc2cc(C(=O)C3CCC(OC)CC3)ccc2nc1C +NC(=O)c1ccc2[nH]c(-c3ccc(C(O)c4ccccc4)cc3)nc2c1 +CC1CCC(C)N1C(=O)c1ccc(-c2ccc(OCCCN3CCC(O)C3)cc2)cc1 +CN1C(=O)CC(c2ccccc2)C1C(O)c1ccc(S(=O)(=O)N2CCOCC2)s1 +COc1cc(Nc2nc3n(n2)CCC(O)N3Cc2ccccc2)ccc1-n1cnc(C)c1 +CC(C)Oc1ncc(-c2nc(-c3cccc4c(CCC(=O)O)c[nH]c34)no2)cc1C(F)(F)F +CCNC(=O)c1cc2c(N3CCOCC3C)ccnc2[nH]1 +Nc1nc(N)c2nc(CNc3c(Cl)cc(C(=O)NC(CCCNC(=O)c4ccccc4C(=O)O)C(=O)O)cc3Cl)cnc2n1 +CCCc1cc(C(=O)NC(Cc2ccccc2)C(O)CNCc2cccc(C(F)(F)F)c2)cc(N2CCCCS2(=O)=O)c1 +Cc1nn(C)c(-c2ccc(F)cc2F)c1-c1ccc2c(c1)NC(=O)CO2 +O=C(O)CCc1c(C=C2C(=O)Nc3ccc(C(=O)O)cc32)[nH]c2c1CCCC2 +CCCCOc1cc(-c2cc3c(O)nc(C)nc3cc2C(C)C)ccc1Cl +COc1cc(CNC(=O)c2c(OC)cc(O)c3c2OC2=CC(O)=C(C(C)=O)C(=O)C23C)c2ccccc2c1 +Cn1c(Cl)nc(C(=O)N2CCC2)c1C(=O)NCCc1nc2ccccc2n1C +C=CCC1CN(C)CCC1(OC(=O)CC)c1cccc(O)c1 +O=C(Nc1ccc(C(=O)N2CCOCC2)cc1)N1Cc2ccncc2C1 +COc1ccc2c(c1)C1(CCNCC1)C(=O)N2Cc1cc2cnc(C#N)nc2n1CC(C)(C)C +CCCC(=O)c1sc2cnccc2c1Nc1ccc2c(c1)CCC2=NO +CS(=O)(=O)N1CCC(C(O)c2cncnc2Cc2ccccc2)CC1 +Cn1cc(C2=C(c3nc(N4CCNCC4)nc4ccccc34)C(=O)NC2=O)c2ccccc21 +COc1cc(Nc2ncnc3ccc(-c4ccc(CN5CC6C(CO)C6C5)cc4)cc23)ccc1Oc1ccccc1 +CC(C)CC(C(N)=O)N(Cc1ccc(CCl)cc1)S(=O)(=O)c1ccc(Cl)cc1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(c2ccc(F)cc2)CCCC1 +CCC(CC)(NC(=O)c1ccc(C2CC2)c(S(=O)(=O)CC(C)C)n1)C(=O)NC +CC1CCC(Cn2c(N3CCOC4CCCC43)nc3cc(C(=O)NS(C)(=O)=O)nc(-c4cncc(Cl)c4)c32)CC1 +Cc1ccc(NC(C(=O)CCc2ccncc2)c2ccccc2Br)c(Cl)c1 +CC(=O)c1cn(CC(=O)N2C(C(=O)Nc3cccc(Br)n3)CC3CC32)c2ncccc12 +CCNC1CCc2cc(OC)c(OC)c(OC)c2-c2ccc(OC)c(=O)cc21 +CC(C)C(O)CC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2ccccc2[nH]1 +Cn1ncc(OC(F)F)c(-c2ccc(CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)c1=O +COCCN1CCN(C(=O)c2cc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3)cs2)CC1 +COc1cscc1C(=O)NC1C(CC=CCCCC(=O)O)CC2CC1C2(C)C 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+CC(C)(C)OC(=O)N1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)CC1 +O=C(Nc1ccc(C(=O)N2CCc3c([nH]c4ccccc34)C2)cc1)N1Cc2ccccc2C1 +COc1n[nH]c2cc(NC(=O)NC(c3ccc(F)c(C)c3)C(C)(C)O)nc(CO)c12 +O=C1c2cnc3[nH]ccc3c2N(C2CCC(CNCC(F)(F)F)CC2)CN1CC1CC1 +O=c1ncn2nc(Sc3ccc(F)cc3)ccc2c1-c1c(Cl)cccc1Cl +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCCC23CCCN2CCC3)cc1F +Cc1c(N(Cc2cc3cccc(Cl)c3s2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +COc1ccc(S(=O)(=O)N2CC(C(=O)NCCCn3ccnc3)c3ccccc32)c2ccccc12 +CC1CCN(C(=O)C(CCn2cccc2C#N)NS(=O)(=O)c2ccc3[nH]ccc3c2)CC1 +COc1ccc(N(C)c2nc(C)nc3cc(C)[nH]c23)cc1 +O=C(Cc1ccc2ccccc2c1)Nc1cnc(-n2cccn2)nc1O +CC(NS(C)(=O)=O)c1ccc(CN2CCOC(c3ccc(F)cc3)C2)cc1 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncon2)c1 +O=c1oc2c(Br)c(O)c(Br)cc2cc1-c1nnn[nH]1 +N=C(N)Nc1ccc(N2C(=O)N(Cc3ccccc3)N=C(C3CCCCC3)c3ccccc32)cc1 +Cc1nc2c(cc1Nc1nc(Cl)cn(C(C)C3CC3)c1=O)COC2 +Cc1ccccc1C(CC(=NO)c1ccncc1)c1ccc(Br)cc1 +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(OC)cc1)C(=O)c1ccccc1C +CC(C)(C)c1nc2cc(S(=O)(=O)c3ccco3)ccc2n1CC1CCOCC1 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+O=C(NCc1nnc2n1CCCCC2)c1csc(-c2ccccc2)n1 +Cc1cccc(N2CCN(CCCCN3C(=O)CSC3(C)C)CC2)c1 +N#Cc1cccc2c(C3=CCN(CCC4OCCc5cc(C(N)=O)ccc54)CC3)c[nH]c12 +CCCC(C)CN1CCC(c2ccc(C(=O)N(C)C)cc2)(c2cccc(O)c2)CC1 +O=C(Cc1ccccc1)NC1CCN(Cc2ccc3cc(F)ccc3c2)C1 +COCCc1sc(S(=O)(=O)NC(=O)Nc2cc(C(F)(F)F)cc(C)n2)cc1C +COc1cc(CNc2ccc(Cc3c[nH]c4ncc(C)cc34)c(F)n2)c(F)cn1 +N#Cc1ccc(Cl)c(C(=O)c2c[nH]c3ncc(-c4cnn(C5CCNCC5)c4)cc23)c1 +NC(=O)c1cccc2c1C(=O)N(C1CCN(C3CCOCC3)CC1)C2 +Cc1nn(C)cc1-c1cnc(N)c(-c2ccc(C(=O)NC(CO)c3ccccc3)c(F)c2)c1 +O=C(O)C1CC1C(=O)c1ccc(N(Cc2ccc(Cl)cc2)CC2CC2)cn1 +CSc1nc(NC2CC(CO)C(O)C2O)c(-c2nc3ccccc3s2)c(=O)[nH]1 +CN1C(=N)NC(CCC2CCCCC2)(CC2CCCC(NC(=O)Nc3ccccc3)C2)C1=O +COc1cc(OC)cc(N(CCNC2CCN(S(N)(=O)=O)CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1nn(C)c(C)c1-c1cc(Nc2ccc(OC(F)(F)F)cc2)ncn1 +CC(=O)NC(C)c1ccc(OC2CN(c3cnc4ccccc4n3)C2)cc1 +CN(C)CCNC(=O)c1cccc2cc3cccc(F)c3nc12 +N#Cc1ccc(C(O)(c2cscn2)C(F)(F)F)cc1C(F)(F)F +Cc1cc(O)cc(C)c1CC(N)CN1Cc2ccccc2CC(NC(=O)Cc2ccccc2)C1=O +O=C(Nc1ccc(CC(NC(=O)C2CCC(=O)N2Cc2ccccc2)C(=O)O)cc1)c1ccccc1[N+](=O)[O-] +COc1ccc(OC)c(C=CC(=O)C(=Cc2ccc(O)c(F)c2)C(=O)C=Cc2cc(OC)ccc2OC)c1 +O=C(c1nn(-c2ccc(CN3CCC(O)C3)cc2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CN1CCN(C(=O)Nc2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +COc1cc(C(C)C)c(Oc2cnc(NCCNC(C)=O)nc2N)cc1I +CC(=O)N1CCC(C(=O)N2CCC(N(C)C(=O)c3ccc(C)cc3)C(c3ccc(Cl)c(Cl)c3)C2)CC1 +COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(Cc3ccncc3)c2c1 +COC1COCCC1NC1CC2CCCC2(C(=O)N2CCc3ncc(Br)cc3C2)C1 +CC(C)c1n[nH]c(Cl)c1-c1ccnc(Nc2ccc(N3CCC(N(C)C)CC3)cn2)n1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)C1CCC(=O)N1C +O=C(NC1CC1)c1ccc(-c2cnc3c(NCC4CCOCC4)cc(Oc4ccccc4F)nn23)cc1 +NC1CCC(Nc2cc(-c3cnc(Cl)c(NCC4CCOCC4)n3)c(Cl)cn2)CC1 +Cc1ccccc1C(=O)c1cnc(NCCCNS(=O)(=O)c2cccc(F)c2)s1 +O=C(Nc1ccc(C2=CCN(C(=O)c3cnccn3)CC2)cc1)N1Cc2ccncc2C1 +COCCNc1nc(-c2cnn(CCO)c2)cc2ncn(C)c(=O)c12 +O=C(O)c1ccc(-c2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)nc1 +O=c1ccn(CCCCCS(=O)(=O)NCc2cccc(OCC3CC3)c2)c(=O)[nH]1 +c1cncc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)c1 +Cc1ccccc1S(=O)(=O)NC(CNC(=O)c1ccccc1)C(=O)O +Cc1ccc(O)c(Oc2ccc(C#N)c(C(F)(F)F)c2)c1 +CC1CN(C(=O)OC2(C(F)(F)F)COC2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +COc1ccccc1N1CCN(CC(O)CN2C(=O)NC(=Cc3ccc(N(C)C)cc3)C2=O)CC1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2csc(Cc3ccccc3)n2)c1 +CCCCN(CC)c1cc(C)nc2c1NC(=O)CN2c1ccc(C(C)C)cc1Cl +Cc1cccc(NC(=O)Nc2c(-c3ccccc3)c3cc(C)c(C)cc3c(=O)n2C)c1 +Cc1cc2[nH]ncc2c2sc(NC(=O)C3(Nc4ccc(Cl)cc4)CC3)nc12 +NC(=O)c1cc(OC2CCNC2=O)nc(C2=CCC(Oc3ccc(C(F)(F)F)cc3)CC2)n1 +O=C(NO)C1(S(=O)(=O)c2ccc(OCCCn3nnc(-c4ccc(OC(F)(F)F)cc4)n3)cc2)CCOCC1 +N#CC1CC(NC2CC2)CCC1n1cc(C(N)=O)c(Nc2ccc(S(=O)(=O)C(F)(F)F)cc2)n1 +CNCCN1CCC(OCc2ccc(-c3ccccc3)cc2)CC1 +CCCCc1nc(NCc2ccccc2[N+](=O)[O-])c2sccc2n1 +CC(C)n1cc(C(=O)c2ccnc(NC(=O)Cc3coc(C4CC4)n3)c2)c2cnccc21 +CCN(CCOC)c1ccc(NC(=O)c2nc(-c3ccccc3)oc2C(F)(F)F)cn1 +CN(CC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)C(=O)c1ccc(Cl)s1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cnnn1-c1ccc2c(c1)OCCO2 +COc1ccc2cc3[n+](cc2c1OCCSc1ccccc1)CCc1cc2c(cc1-3)OCO2 +C=CC(C)(C)c1c(OC)cc(O)c2c(=O)c(OC)c(-c3ccccc3)oc12 +C=CC(C)(C)c1cc(CCCc2cc(O)c(O)c(CC3OC3(C)C)c2CC=C(C)C)c(O)cc1O +CC1(N)CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(Cl)c(O)c(Cl)c4)cc23)CC1 +O=C(Nc1ccccc1-c1nc2ccccc2[nH]c1=O)c1cccnc1 +CN(CCC1CN(C(=O)OCc2cc(Cl)cc(Cl)c2)CCO1)C(=O)c1c[nH]c(=O)o1 +Cc1ccc(C(=O)N2CCOCC2Cc2cc(-c3ncccn3)ccc2F)c(-n2nccn2)c1 +COc1ccc2c(c1)C(=O)C(=Cc1cc(Br)c(O)c(Br)c1)C2=O +CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(CCCI)C1CCC(CO)CC21 +Cc1cccc(C)c1Oc1cc(Nc2ccc(C#N)cc2)c([N+](=O)[O-])cc1[N+](=O)[O-] +COc1cccc(-c2cc(C(N)=O)c3[nH]c4cc(NC(=O)C5CCOCC5)ccc4c3c2)c1 +CCN(C(=O)c1ccc(CNc2ncnc(N3CCc4cc(F)ccc4C3)n2)cc1)c1cccc(C)c1 +COc1cc(CNC(=S)NC(CCc2ccc(C)c(C)c2)COC(=O)C(C)(C)C)c(I)cc1O +CC(C)(C)C(CO)NCC(=O)N1CCc2ccccc2C1C1CCCCC1 +CN(C(=O)C1C(c2ccccc2)=C1c1ccccc1)C1CCCCC1N1CCCC1 +O=C(NCCCc1c[nH]cn1)NCCCN(Cc1ccc(Cl)c(Cl)c1)c1ccc(Br)cn1 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccc(CN4CCC5(CC4)COC5)cc3)cc12 +O=S(=O)(c1cccc(F)c1)c1cccc2oc(N3CCNCC3)nc12 +COc1cccc(OC)c1OCCNCCOc1ccccc1OCc1ccccc1[N+](=O)[O-] +CC1(C)C2CC3OB(C(CCCCN)NC(=O)C4CCCN4C(=O)c4ccccc4Cc4ccccc4)OC3(C)C1C2 +COc1ccc(OC)c(N2CCOc3cc(S(=O)(=O)Nc4nccs4)ccc32)c1 +CNC(C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl)c1ccccc1 +CC1(O)CCC(Nc2c(C(N)=O)cnn3cc(-c4ccccc4C(N)=O)cc23)CC1 +CC(C)=CCOc1cc(Oc2ccc(S(=O)(=O)N3CCC(F)C3)cc2)cc(C(=O)Nc2cc(C)n(C)n2)c1 +CCN(c1ccc(OCc2ccccc2)cc1)C1CCN(C(=O)C(CC(C)C)NC(=O)N2CCCCCC2)CC1 +COc1cc2c(cc1OC(C)C)C(c1ccc(Cl)cc1)N(C1CCC(C(C)(O)CCC(C)C)CC1)C(=O)C2 +N#Cc1nc(Nc2ccc([N+](=O)[O-])cc2)nc(NC2CCCCC2)n1 +O=C(CCO)NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1 +NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1cccnc1-n1cc2ccccc2n1 +COc1cc(N2CCOCC2)ccc1Nc1ncc(Cl)c(Nc2ccccc2P(C)(C)=O)n1 +COc1cc(C(=O)Nc2cnc(C)c(-c3cc(N4CCOCC4)c(=O)n(C)c3)c2)ccc1F +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCc2ccc(CNC(=O)c3ccc(Cl)cc3)cc2)C1 +CCOC(=O)c1c(-c2cccc(OC)c2)[nH]c2cc(OC)c(Cl)cc2c1=O +COc1ccc2[nH]c(C(=O)c3cccc(N)c3)cc2c1 +COc1cccc(C2(c3cccc(OC)c3)CC3c4ccccc4C2c2cccc[n+]23)c1 +Cc1c(Nc2c(C#N)cncc2C=CCCN2CCC(N(C)C)CC2)ccc2[nH]ccc12 +O=C1NC(=O)C(c2ccc(-c3ccc4ccccc4c3)[nH]c2=O)(C2CCCCC2)O1 +CCc1nc2c(-c3ccc(OC)nc3C(F)(F)F)ccnc2n1C(C)CC +O=C(COc1cccc2[nH]cc(S(=O)(=O)c3ccc4ccccc4c3)c12)NS(=O)(=O)c1cc(F)cc(F)c1 +CCOc1ccc(C(=O)Nc2ccc(C3CCCNC3)cc2)nc1 +COc1cccc(-c2ccc3c(c2)CCN(CC(=O)Nc2cc(Cl)cc(Cl)c2)C3C2CCN(C3CCCC3)CC2)c1 +O=C(Nc1ccc(C2CNCCO2)cc1)c1cc(-c2cccc(Cl)c2)[nH]n1 +CC(=NOCc1ccc(-c2ccccc2)cc1)c1ccc(CNCCC(=O)O)cc1 +Cn1ncc(NCc2ccncc2)c1C(=O)Nc1cccc(C(F)(F)F)c1 +CCCOCCn1c(=O)c(NCC(=O)N2CCCC2)nc2cnc(-c3ccc(OC)nc3)cc21 +COc1cc(-c2cn(C3CC(C(F)(F)F)CCN(Cc4ccccc4)C3=O)nn2)ccc1-n1cnc(C)c1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-c2csc(C)n2)c1 +CC(Nc1nc2c(cnn2C2CCCC2)c(=O)[nH]1)C(=O)Nc1ccc(F)cc1 +O=C1NC(CCCN2CC=C(c3ccccc3)CC2)=NC2CCOCC12 +N#Cc1cc(Cl)cc(Oc2cc(OCc3nc4cccc(Cl)c4[nH]3)ccc2Cl)c1 +Cc1ccc(CC(=O)Nc2cc(-c3ccccc3-c3nnn[nH]3)ccc2N2CC3CC2CN3Cc2ccccc2)cc1 +Cn1nccc1-c1cc(Cl)ccc1-c1cn(C)c2cc(S(=O)(=O)Nc3ncns3)ccc12 +CNC(=O)C(=O)C(CCCCN)NC(=O)CN(C)C(=O)c1ccccc1Sc1ccccc1C#N +COc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CCC2)[nH]1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NCc4cccc(Cl)c4)nc23)N1 +COCC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1ccccc1 +Nc1cccc(Cn2c(-c3ccc(Oc4cncnc4)cc3)ccc2-c2ccccc2Cl)n1 +CNC(=O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12 +CC(c1ccccc1Cl)N1CCC(n2c(O)nc3ccccc32)CC1 +COc1cc2c(cc1OC)C(=O)C(C(=O)Nc1ccc(C)cc1)C2 +O=C(NCCc1ccc(Cl)c(F)c1)c1ccc2cnc(NC3CCOCC3)cc2n1 +CC1(C(=O)N(CCCC(=O)O)Cc2ccc3ccoc3c2)CCN1C(=O)c1csc2ccccc12 +CCNC(=O)c1cc2c(N3CCCC3c3cccnc3)ccnc2[nH]1 +Oc1ccc2c3c1OC1c4[nH]c5c(OCc6ccccc6)cccc5c4CC4(O)C(C2)N(CC2CC2)CCC314 +COc1ccc(Oc2c(Cl)cnn(-c3cccc4c3CCCC4)c2=O)cc1 +O=C1CCC(=O)N1c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F +O=C(O)CS(=O)(=O)N1CCC(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +Nc1nc(SCc2ccccc2)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1c(C(=O)NCCc2ccc(Cl)cc2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +NC(Cc1ccc(O)cc1)C(=O)Nc1nc2ccc(C(=O)c3ccccc3)cc2[nH]1 +CNCCCN1Cc2ccccc2N(c2ccc(F)c(F)c2)S1(=O)=O +CCCC(c1ccccc1)N(CCC)c1nc(-c2ccc(Cl)cc2OC)n(C)n1 +O=C(O)c1cccc(COc2cccc(CCS)c2C(=O)O)c1 +Cc1cn(C2CC(O)C(CNC(=O)Nc3ccc(OCc4cccc(Cl)c4)cc3)O2)c(=O)[nH]c1=O +CC(OCC1(c2ccccc2)CC(NS(C)(=O)=O)C(=O)N1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(C)(C)CC(=O)N1CCC(N(c2ccc(Cl)cc2)c2cccnc2)CC1 +CC(O)Cn1c2cnccc2c2cnc(Nc3ccc(N4CCNC(C)C4)nn3)nc21 +O=C(Nc1ccc2c(c1)CCNC2)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CCCS(=O)(=O)N1CCCC(Nc2ncccc2-c2cnc3nc[nH]c3n2)C1 +CCOc1cc(=O)n(C)cc1-c1cc(CS(C)(=O)=O)ccc1Oc1ccc(F)cc1F +CCC12CCC(=O)C(Br)=C1c1ccc3[nH]ncc3c1C2 +CC(C)(C)OC(=O)n1c(-c2ccc(CCC#N)cc2)cc2ccccc21 +CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N(C)C)c1=O +O=C(NC1CCCCCCC1)c1ccc(CN2C(=O)Nc3ccc(Cl)cc3S2(=O)=O)cc1 +O=[N+]([O-])c1ccc(-c2csc3ncnc(N4CCC(COCCN5CCCC5)CC4)c23)cc1 +COc1cc2c(cc1OC)C1=NOC(CN3CCN(CC(C)=Cc4ccsc4)CC3)C1CO2 +COc1ccc(-c2cc(-c3ccc(F)cc3F)n3c(CN4CCOCC4)cnc3c2C#N)c(OC)c1OC +CC(CCc1ccc(Oc2ccccc2F)cc1)(C(=O)NO)S(C)(=O)=O +O=S(=O)(c1ccc2oc(N3CCNCC3)nc2c1)c1cccc2ccccc12 +COc1ccc(-c2cn(C(C)=O)c(=O)n2-c2cc(OC)c(OC)c(OC)c2)cc1 +CCn1c(=Cc2ccc3ccccc3[n+]2CC)sc(=C2Sc3ccccc3N2C)c1=O +CC(C)Cc1cn(-c2nc(C(=O)O)cs2)c2cc(C(F)(F)F)ccc12 +Cc1cc(C)cc(S(=O)(=O)n2c(SCC(=O)Nc3ccc(C)cc3Cl)nc3ccccc32)c1 +COC1CN(c2nc(-c3cccc(C)c3OCc3cc(C)c4c(c3)CCN(CC3COCCO3)C4)cs2)CCC1C(=O)O +O=C(O)CC(NC(=O)OCc1ccccc1)C(=O)COC(=O)Cc1c(Cl)ccc(Cl)c1Cl +Cc1nc2ccc(N=c3[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n3Cc3ccc(Cl)cc3)cc2o1 +CC(O)(C(=O)Nc1ccc(S(=O)(=O)NCCN2CCCC2)cc1Cl)C(F)(F)F +CCS(=O)(=O)N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +CCN1C(=Cc2sc3ccc(Cl)cc3[n+]2CC)C=Cc2cc(OC)ccc21 +CCN1CCN(c2nc3ccccc3c3c2COc2ccccc2-3)CC1 +CC1=C(c2ncnn2-c2ccccc2F)C(c2ccc(Cl)c(Cl)c2)n2nccc2N1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])C(=O)Nc1cccc2ccccc12 +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2cc3ccccn3n2)c1 +CCc1ccc2c(c1)c(-c1ccc[nH]c1=O)c(C(=O)NS(=O)(=O)C1CC1)n2Cc1cc(F)ccc1F +NS(=O)(=O)c1ccc(CNc2ncnc(NCc3ccccc3)c2[N+](=O)[O-])cc1 +CNC1CCN(C(=O)c2ccc(-c3[nH]nc4c3C(=O)c3c(NC(=O)NN5CCOCC5)cccc3-4)s2)C1 +CCCCNC(=O)C(C)CC(O)C1CSCCCCCSCC(NC(C)=O)C(=O)NC(C)C(=O)N1 +CN(C)C1CN(c2cc(-c3cnc(N)c(OC(F)F)c3)nc(N3CCC(F)(F)C3)n2)C1 +CCCCCCCCCCCCC(=O)N1CCC2C(C)C(O)CCC2(C)C1 +OCC(NC1CCN(CCCc2c[nH]c3ccc(Cn4cncn4)cc23)CC1)c1ccccc1 +COc1ccc(C2(C(=S)NCCCn3cncc3C)CC2)cc1OC +O=c1[nH]nc(Cc2ccc(-c3ccc(Cc4n[nH]c(=O)c5c4CCCC5)cn3)nc2)c2c1CCCC2 +CN(C)CCc1c[nH]c2ccc(CCN3CCN(C)S3(=O)=O)cc12 +COc1cc2ncnc(N3CCN(C(S)=Nc4cccc([N+](=O)[O-])c4)CC3)c2cc1OC +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1NC(=O)c1cnc(NC(C)C)nc1 +O=C(O)CN1C(=O)C(=Cc2ccc(-c3cc(C(F)(F)F)ccc3Cl)o2)SC1=S +COCCn1cnc(CCNc2cc[nH]c(=O)c2-c2nc3c(C)cc(N4CCOCC4)cc3[nH]2)c1 +CN(C(=O)c1ccc(N(C)C2CCN(c3ncnc4[nH]ccc34)C2)nc1)c1ccc(F)cc1 +CC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ccc(OCC5CC5(F)F)cn4)C3)cc2)s1 +CCCCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3cccc(OC)c3)CC2)cc1 +COc1ccc(N(C)c2cc(OC)c(OC)c(OC)c2)cc1 +O=C(C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1)N1CC(c2ccccc2)(c2ccccc2)C1 +COc1ccc(C=Cc2ccc3ccc(C(=O)O)c(O)c3n2)cc1O +Cc1cc(N(C)CCN(C)C)nc2ccc(NC(=O)c3ccc(-c4ccccc4)cc3)cc12 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+CCCCCN(C)C(=O)C(=O)c1c(-c2ccc(Cl)cc2)[nH]c2ccc(Cl)cc12 +O=C(CCCCC1CCSS1)NCC(O)CNc1c2c(nc3cc(Cl)ccc13)CCCC2 +COc1nc(Nc2ccc(C#N)c(OCC=C(C)C)c2)nc(OCCN2CCN(C)CC2)n1 +COc1ccc(Nc2snc(SCc3ccc(Cl)cc3)c2C(N)=O)cn1 +O=C(Nc1cccc(-c2ncnc3cc(-c4ccncc4)sc23)c1)c1cccc(C(F)(F)F)c1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1NC1CCOC1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nnc(Nc2cccc(Oc3ccccc3)c2)o1 +Cc1c(C(C)c2c(F)cccc2F)nc(Nc2ccc(C#N)cc2)[nH]c1=O +O=C(NCc1ccc(-c2ccccc2)cn1)C(O)C(O)C(=O)N1CCCC1c1cccc(Cl)c1 +CN(C)CCC=Cc1ccc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2c1 +CC(C)c1ccc(C(O)(c2ccc(C(F)(F)F)cc2)c2cccnc2)cc1 +O=c1[nH]c(C2CNCC2c2ccc(C(F)(F)F)cc2)nc2ccc(-c3cn[nH]c3)cc12 +COc1ccc(C(C)=NNC(=O)C2CC2c2ccccc2)cc1OC +O=C(NC(Cc1ccccc1)C(=O)NC(CCS)C(=O)O)c1cc2ccccc2[nH]1 +NC(=O)c1cc(-c2ccn[nH]2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc12 +CCCOc1ccc(NC(=O)c2ccc(F)cc2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 +COc1ccccc1N1CCN(CCn2nc(N3CCN(C(=O)c4ccco4)CC3)ccc2=O)CC1 +Cc1sc(N)nc1-c1ccc2[nH]c3c4c(c5c(c3c2c1)C(=O)NC5=O)CCC4 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+CNc1nc2[nH]c(-c3cccc(CNC(=O)C4(C)CC4)n3)cc2c2c1ncn2C +Cc1ccc(N2CCOCC2)cc1N1CCN(C(=O)c2cccc(Cl)c2Cl)CC1=O +Cc1cccc(-n2c(C)nc3ccc(C(=O)c4c(C)nn(C)c4O)cc3c2=O)c1 +C=CCC1C(=O)N(CCN(C)C)c2cccc(C(F)(F)F)c2CC1c1ccc(OC)cc1 +N#CCC1(n2cc(C(N)=O)c(Nc3cccnc3)n2)CCN(C(=O)OCC(F)(F)F)CC1 +CCc1ccc(C(=O)NCC2c3[nH]c4ccccc4c3CC3C4c5[nH]c6ccccc6c5CC(C(C#N)N23)N4C)cc1 +N=C(N)c1ccc2cc(C(=O)Nc3ccccc3)cc(Br)c2c1 +O=C(NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1)C1CC(Cl)C1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1CCc2c(Br)cccc21 +CCCCN1CC2(CN1Cc1ccc(-c3ccccc3S(=O)(=O)NC(=O)c3ccccc3)cc1)C(=O)CCC2=O +COC(=O)c1c(C(=O)OC)c(C(C)C)n(CCC2CC(O)CC(=O)O2)c1-c1ccc(F)cc1 +N#Cc1ccc2ccc(=O)n(CCN3CCC(NCc4ccc5c(n4)NC(=O)CO5)CC3)c2c1 +CS(=O)(=O)NCCn1ccc2cc(C(=O)N3CCC(N4C(=O)OCc5ccccc54)CC3)ccc21 +CN(Cc1ccc2nc(N)nc(N)c2n1)c1ccc(Cl)c(Cl)c1 +CC(=O)Nc1cccc(OP(=O)(Oc2cccc(NC(C)=O)c2)C2CCCN2C(=O)C2CCCN2)c1 +COc1ccccc1CN(CCCCCCCCN(Cc1ccccc1OC)C(=O)CCCCCN)C(=O)CCCCCN +O=C(NCCc1ccc(-c2ccccc2)cc1)C(CC#Cc1ccccc1F)NCP(=O)(O)O +CN(c1cc(F)c(C#N)c(F)c1)C1CCN(c2ncnc3[nH]ccc23)C1 +CN(C)CCNc1nc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2o1 +CNC(=O)C(C)(NC(=O)c1cc(OCC(F)(F)F)c(C2CC2)cn1)c1noc(C)n1 +COC(=O)C1(C)CCCC2(C)c3cc(Br)c4nc(N=Cc5cc(Cl)cc(Cl)c5O)[nH]c4c3CCC12 +N#CSc1c(-c2cccc(C(F)(F)F)c2)[nH]c2ccccc12 +O=C1C=C(c2ccccc2)C2(CCN(c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)CC2)O1 +Cn1cc(-c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)cn1 +O=C(O)CCCCCC(CNS(=O)(=O)c1ccccc1)c1cccnc1 +FC(F)(F)c1ccc(Nc2nc(N3CCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +CC1CN(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4Cl)nc23)CCN1C(=O)OC(C)(C)C +CC(OC1CCC(N(C)CC2CCC(=O)N2)C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=c1ccc2c(OCCCCCOc3ccccc3)c3ccoc3cc2o1 +CC(C)CCNC(=O)c1ccc(N2CCC(Oc3cccc(F)c3F)CC2)nn1 +COc1ccc(-c2nnc(C(=O)N3CC(Oc4ccc(CN(C)C)c(C)c4)C3)o2)cc1 +O=c1ccc2ccccc2n1CCCCCN1CCN(c2cccc3sccc23)CC1 +Cn1ccc(COc2cc(F)c3nc(C4CCCCC4C(=O)O)n(Cc4ccc(N5CC(F)(F)C5)cc4)c3c2)n1 +CC(c1ccccc1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 +COc1cc(CC2C(C)(C)CC(C)=CC23CC3)c(OC(C)=O)cc1Br +CC1CN(c2nnc(N3CCC(N4CCCCC4)CC3)s2)CC(C)O1 +COc1ccc(F)cc1-c1c[nH]c2c(NC(C)=O)cccc12 +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCc3ccc(CC(C)C)cc3)ccc21 +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3C#N)cc2)cc1 +Cc1ccc(-n2nc(NC(=O)C3CNC(=O)C3C)cc2-c2cccc(OC(F)(F)F)c2)cc1 +Cc1cc(NC(CCCCNCc2ccc(Cl)cc2)C(=O)NO)cc(C)c1F +O=C(Nc1ccc2cc(CN3CCCC3)cnc2c1)c1ccc(-c2ccc(F)cc2)nc1 +Nc1nc2c(s1)CN=C(c1ccccc1F)c1cc(Cl)ccc1-2 +COc1cccc(C(=O)Nc2ccc(OC)cc2C(=O)Nc2ccc(N3CCCCC3=O)cc2)c1 +N#CCCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +NC(=O)N1CCCc2cc(-c3cncc(-c4ccc(S(=O)(=O)NCCO)cc4)c3)cnc21 +OC(CNc1ccc(F)c(F)c1)(c1ccc(Cl)cc1)c1nnn(Cc2ccccc2)c1-c1ccc(Cl)cc1 +O=C(CC1CCCC1)Nc1ccc(NC(=O)N2Cc3ccc(-c4ccncc4)cc3C2)cc1 +Clc1ccc2c(NCCCCCCCCNc3c4c(nc5cc(Cl)ccc35)CCCC4)c3c(nc2c1)CCCC3 +COc1ccc(OCC(=O)Nc2ccc3nc(N4CCN(C)CC4)cc(C)c3c2)cc1 +COc1ccc(-c2cc3c(N)ncnc3nc2-c2cccs2)cc1Br +O=S(=O)(NC1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC1 +CC#CCOc1ccc(S(=O)(=O)N2CCCSCC2C(=O)NO)cc1 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+CN(C)S(=O)(=O)c1c(Cl)ccc(NC(=NC#N)Nc2ccccc2F)c1O +COc1cc(-c2cn(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)cn2)cc(OC)c1O +CCCOc1cc(OCCCCN)cc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 +CSc1ccc(NC(=O)c2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1 +N#Cc1ccccc1OCC(O)CNCCNC(=O)Nc1ccc(OCCF)nc1 +COc1ccc2c(c1)C(=O)C(c1ccc(C(C)(C)C)cc1)=[N+]2[O-] +CNC(=O)C(=O)CCCCCCC(=O)Nc1ccc(-c2ccccc2)cc1 +COc1ccc(Cl)cc1N1CCN(C(=O)c2cc(-c3ccc(Cl)cc3)n[nH]2)CC1 +NC1=Nc2ccc([N+](=O)[O-])cc2C2CCCC12 +COC(=O)C(NC(=O)CCC(=O)C=Cc1ccc2c(c1)OCO2)C(C)C +COc1ccccc1N(CC(=O)N1CCCCC1)S(=O)(=O)c1ccccc1 +O=C(CCCCCCCC(=O)c1ccc(-c2ccccc2)cc1)NO +Cc1cc(NC(=O)OC(C)(C)C)nn1Cc1cc(Cl)ccc1OCc1ccccc1 +COc1ccc(NC(=O)Nc2ccc3c(c2)c2c4c(c5c(c2n3CC(C)C)CCc2nn(C)cc2-5)C(=O)NC4)cc1 +N#Cc1cc(S(=O)(=O)Nc2cscn2)ccc1Oc1ccc(Cl)cc1-c1cn[nH]c1 +COc1ccc(-c2sc3cc(OC)ccc3c2C(=O)c2ccc(OCCN3CCCCC3)cc2)cc1 +CN(C(=O)c1ccc(OCC2CC2)cn1)C1Cc2ccc(CN3CCCCC3)cc2C1 +O=C(C=Cc1ccccc1)c1ccc(Nc2nc(-c3ccccc3)nc3ccccc23)cc1 +O=C(O)C1=C(C=Cc2cccc[n+]2[O-])CS(=O)(=O)C2C(=Cc3ccccn3)C(=O)N12 +O=C(NC1CC1c1ccccc1)N1CCC(c2ncon2)CC1 +CSCCC(NC(=O)c1cccc(CN(Cc2ccc(C#N)cc2)Cc2cncn2Cc2ccc(C#N)cc2)c1)C(=O)O +O=C(COc1ccccc1)Nc1nc2nn(CCCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +CCCCC1CCN(C(C)C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(OCCC)CN2)C1=O +NC1(c2ccc(-c3nc4ccc(O)cn4c3-c3ccccc3)cc2)CCC1 +CCc1nn2ccc(Cl)cc2c1C(=O)NCc1ccc(N2CCC(c3ccc(OC(F)(F)F)cc3)CC2)cc1 +CSc1nn(-c2ccccc2)c2cc(N3CCN(C4CCNC4)C3=O)ccc12 +Cc1ccc(NC(=O)Nc2ccc(-c3csc4c(-c5cnn(C)c5)cnc(N)c34)cc2)cc1 +CCCCCC(C)NC(=O)C1CCN(Cc2ccc(Cl)cc2Cl)CC1 +CCn1c2ccccc2c2cc(NC(=O)CCN3CCOCC3)ccc21 +Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CN)cc3)ccc2n1 +NC1=NC(c2cc(NC(=O)c3ncc(Br)cc3C(F)F)ccc2F)(C(F)F)C2CC2O1 +Cc1ccc(C(Nc2c(Nc3cccc(C(=O)N(C)C)c3O)c(=O)c2=O)C(C)F)o1 +COc1ccc(N(C)Cc2ccc3nc(N)nc(N)c3n2)c(OC)c1 +CCN(CC)c1cccc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(C)c34)cc2)c1 +CCCC(C)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)c(Cl)c1 +Cc1cccc(Nc2ncnc3c2sc2ccc(N)cc23)c1 +Nc1ncnc2cc(CN3CCN(S(=O)(=O)c4cc5ccc(Cl)cc5s4)CC3=O)ccc12 +O=C(NCc1ccccc1)c1cnc(Nc2cccc(F)c2)nc1C(F)(F)F +CC1CCC(NC(=O)c2cc3cc(Br)cnc3n(CCN3CCOCC3)c2=O)CC1 +CCCCC(=O)NC(c1ccco1)c1cc(Cl)c2cccnc2c1O +Fc1ccc(CN2CCN(c3ccc(-c4nc5ccccc5o4)cc3)CC2)cn1 +Cc1cncn1CCCNC(=C[N+](=O)[O-])Nc1ccc2c(c1)OCO2 +NCCCCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)N1CCC2(CCc3ccccc32)CC1 +O=C(CCC1CCCC1)NC1CCC(Nc2ccnc3cc(Cl)ccc23)CC1 +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CCC(=O)O)c(CNC(=O)OCc2ccccc2)c1 +COc1ccc(-c2c(N)ncnc2N2CCC(c3nc(-c4ccc(F)c(C(F)(F)F)c4)cn3C)CC2)cc1 +Clc1ccc(OCCN2C3CCC2c2c([nH]c4ccccc24)C3)cc1 +COc1ccccc1CCNCc1ccc(CCNCCc2ccc(O)c3[nH]c(=O)sc23)cc1 +O=C(NCC(CNC(=O)c1ccc[nH]1)OC1OC(CO)C(O)C(O)C1O)c1ccc[nH]1 +N=C(N)NCCCC1NC(=O)CNC(=O)CCSCC(C(=O)O)NC(=O)C(CC(=O)O)NC(=O)CNC1=O +N#CC(=Cc1ccc([N+](=O)[O-])o1)c1nc2ccccc2[nH]1 +CN1CCN(c2cc3c4c(cccc4n2)-c2ccccc2-3)CC1 +Cc1csc(C(C)(O)c2nnc(Nc3cc(C4CC4)n(Cc4c(F)cccc4F)n3)s2)n1 +Cn1c(N2CCOC(c3ccc(F)cc3)C2)nc(-c2ccncc2Cl)cc1=O +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(C(F)(F)F)c(F)c3)cn2CCN2CCCC2)CC1 +CCC(C(=O)OC(C)(C)C)N1C(=O)C(C)(Cc2nnn[nH]2)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC(O)CC2 +Cc1cc(C)cc(Cc2c(C)c(C)[nH]c(=O)c2N(C)C)c1 +CCCOc1ccc(-c2nn3c(NC4CCCC4)nccc3c2-c2ccnc(NC3CCCC3)n2)cc1 +COc1cc(Sc2c(-c3ncco3)[nH]c3ccccc23)cc(OC)c1OC +COc1cc(NC(=C[N+](=O)[O-])NCCCn2cncc2C)cc(OC)c1OC +CCc1nc2n(c1C(=O)N(CCC(F)(F)F)CC1CC1)CCN2c1c(C)cc(C)cc1C +O=C(CSc1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl)C(F)(F)F +COc1ccccc1N1CCN(CCC(=NO)c2ccsc2)CC1 +Cc1nn(Cc2ccc(-c3cc4ccc(Cl)cc4[nH]3)cc2)c(C)c1CC(=O)O +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)SCCc1ccccc1 +O=C1c2ccccc2C(=O)N1CCCCNCCc1ccccc1 +O=C(O)CCCCc1cc2cc(C(=O)NC3CCCc4ccccc43)ccc2c(=O)n1-c1ccc(F)cc1 +O=C1COc2ccc(N3CCc4ccc(F)cc4CC3)cc2N1 +CC1(C)CCC(Oc2cc(F)c(C(=O)NS(C)(=O)=O)cc2Cl)CC1 +COc1ccc(-c2nc3c(c(Nc4ccc(CC(=O)O)cc4)n2)S(=O)(=O)CCC3)cc1F +O=C(NC1Cc2ccccc2C1O)c1cn(-c2ccc(Cl)cc2)c(-c2ccccc2Cl)n1 +CCC(C)(CC)OC(=O)CC(C)NC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +CC1(F)CC(F)(F)C(C)(c2cc(NC(=O)c3ccc(OC(F)F)cn3)ccc2F)N=C1N +Nc1nc(Nc2ccc(N3CCN(C4CC5CCC4C5)CC3)cc2)nn1-c1ncnc2ccc(Cl)cc12 +COc1cc2oc(-c3cn4nc(SC)sc4n3)cc2cc1Br +COC(=O)CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC(C)=O)c2)n1C +CCCOC1C=C(C(=O)O)CC(N=C(N)N)C1NC(C)=O +O=C(Nc1ccccc1)OC1CC2CCCCC2C1C=Cc1ccc(-c2cccc(F)c2)cn1 +Brc1cnc(NCc2cnn(-c3ccccc3)n2)nc1Nc1cc(C2CC2)n[nH]1 +O=C1CC(O)CC(C=Cc2c(Cl)cc(Cl)cc2OCc2cccc(F)c2)O1 +CC(C)(C)OC(=O)NC(C(=O)N1CC2C(C1C(=O)NC(CC1CC1)C(=O)C(N)=O)C2(C)C)C1(C)CC1 +CCCCC(NC(=O)c1ccccc1)C(C)(C)C(=O)OC(=O)C(C)(C)C(CCCC)NC(=O)c1ccccc1 +C#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(C)c1 +CCCCc1nc(-c2ccccc2Cl)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN(C)CCCn1nc2c3c1ccc1c(=O)n(CCN(C)C)c(=O)n(c13)-c1ccccc1-2 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4cc(C(F)(F)F)cc(C(F)(F)F)c4)oc3C)ccc21 +COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)COc3ccccc3[N+](=O)[O-])cc1)CC2 +Cc1cccc(-c2c[nH]c3ncc(-c4cccc(NC(=O)C=CCN(C)C)c4)cc23)c1F 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+O=C1N(Cc2cccc3c2OCCN3)CCCC12CCN(c1cnc3ccccc3n1)CC2 +CC(C)N(CCO)Cc1csc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)n1 +CC(C)(C)c1ccc(CN(Cc2ccccc2)C2=NCC(CBr)S2)cc1 +Cc1cn2cc(C(=O)N3CCOCC3)cc2c(C#Cc2cccc(C(F)(F)F)c2)n1 +CCc1ccc2ncc(C(=O)OCC(CC)CC)c(O)c2c1 +COc1ccc(-n2cnc3c(NC(C4CC4)C4CC4)nc(C)nc32)c(C)c1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCc2ccccc2)C1c1[nH]c(CC)nc1Cl +CC1=C(c2ccc(OCCCN3CCCC3C)cc2)SC2=NCc3ccccc3CN21 +CN(CC=Cc1ccccc1C(F)(F)F)Cc1ccc2c(c1)OCCC2 +Cc1c(Cc2c(F)cccc2F)nc(Nc2ccc(C#N)cc2)[nH]c1=O +Cc1cc2c(cc1Cl)N(C(=O)Nc1ccc(OC(CCN(C)C)c3ccccc3)cc1)CC2 +COC(=O)C1C(OC(=O)c2ccc(I)cc2O)CC2CCC1N2C +COC(=O)CCc1ccc(-c2ccc3c(=O)n(CC4CCC(c5ccccc5)O4)c(N)nc3c2)cc1 +COC1CCC(c2cnc(N)c(-c3ccc(C(=O)NC(CO)c4cc(F)cc(Br)c4)c(F)c3)n2)CC1O +CC(=NO)c1ccc(OCCCc2c[nH]cn2)c(C)c1 +Cc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CNCC2 +COc1ccccc1C1CCCN(c2cc(-c3ccncn3)cc(=O)n2C)C1 +COC(=O)CCCCC(=O)Nc1ccc2c3cccc4c3c(c3ccccc3n4C)[n+](C)c2c1 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(C)s2)CC1 +Cc1cccc(S(=O)(=O)c2c(C(=O)NCCO)[nH]c3ccc(Cl)cc23)c1 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+CC(C)(Cc1c[nH]c2ccccc12)NS(=O)(=O)c1c(N)cc(Cl)cc1Cl +Cc1ccc(Cn2cnc(=O)c3cc(Oc4ncccc4C(F)(F)F)ccc32)cc1 +CCC1CC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2nnn(C)n2)c2nc(C)ccc2N1C(=O)OC(C)C +Fc1cccc(F)c1-c1nc(-c2ccccc2)c(-c2ccc3nc[nH]c3c2)[nH]1 +O=C1COc2cc(Nc3cccc(C(F)(F)F)c3)ccc2N1 +CC(c1ccc(O)c(I)c1)C(O)C=CC1C2CCC(O2)C1CC=CCCCC(=O)O +CN1C2CCC1C1COC(=O)CCCCCC(=O)Nc3ccc(cc3)C1C2 +CCN1CCN(C(c2ccc(C(F)(F)F)cc2)c2cc(Cl)c3cccnc3c2O)CC1 +CC1(C)Oc2cc(-c3cccc(C(F)(F)F)c3)ccc2-c2[nH]c(-c3c(F)cccc3Cl)nc21 +COc1cccc(OC)c1OCCNCC1COC(c2ccccc2)(c2ccccc2)O1 +O=c1cc(-c2cc(F)ccc2F)oc2c1ccc1ccccc12 +COc1ccc(-c2[nH]c(-c3cccs3)nc2CCNS(=O)(=O)N2CCN(c3ccccc3Cl)CC2)cc1 +CCCCc1ncc(C=C(Cc2ccc(OC)s2)C(=O)O)n1Cc1ccccc1Cl +CCC(CC)(c1cc2ccccc2o1)c1c[nH]c2c(NS(C)(=O)=O)cccc12 +O=C(c1cccc(-n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)c1)N1CCCC(CO)C1 +CC(C)CC(N)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)N2CCCC2=O)CC1 +Cc1cc(C(=O)Nc2cc([N+](=O)[O-])ccc2N2CCN(C)CC2)ccc1F +CC1CCN(c2cc(-c3ccnc(NC(C)c4ccccc4)n3)c(-c3cccc(C(F)(F)F)c3)nn2)CC1 +N#CC1(NC(=O)C2CC(S(=O)(=O)c3ccccc3)CC2C(=O)N2CC3CCC(C2)O3)CC1 +CNCc1cc(N)c(Nc2ccc(C#N)cc2)cc1Oc1c(C)cc(C#N)cc1C +O=C1CCN(Cc2ccc(C(F)(F)F)cc2)CC1C(c1ccc(F)cc1)c1ccc(F)cc1 +CC(C)Oc1cccc(-c2ccc(CCNC(=O)c3ccc4c(c3)C3(C)CCN(CC5CC5)C(C4)C3C)cc2)c1 +CC(N)C(=O)N1CCC(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)C(C)C)C3c3ccccc3OC(F)F)cc2)cs1 +Cn1cc(Nc2ncc(Cl)c(NC3C4CCC(C4)C3C(N)=O)n2)cn1 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3ccccc3Cl)o2)c1 +CSc1ccc(C2CCC(OCC3CCN(C(=O)OC(C)(C)C)CC3)CC2)cc1 +N#Cc1c[nH]c2ccc(C3(Cc4ccccc4)CCNC3)cc12 +CC(C)(C)OC(=O)N1CCN(CCCCOc2ccccc2NC(=O)NC23CC4CC(CC(C4)C2)C3)CC1 +COCC[N+]1(C)C2CCC1CC(CC(C#N)(c1ccccc1)c1ccccc1)C2 +C=C(c1ccc(C(C)(O)C(F)(F)F)cc1)N(C1CCC(c2ccccn2)CC1)C1CC1 +CC1CC(c2ccncc2NC(=O)c2nc(-c3c(F)cccc3F)sc2N)CC(N)C1OCCC#N +CCn1c(=N)n(CC(=O)c2ccc(Cl)cc2)c2ccccc21 +COn1c(NC(c2ccc(Cl)cc2)C(C)C)nc2c(c1=O)CN(C(=O)c1ccc(-n3ccnc3)cc1)CC2 +O=C(NCCS(=O)(=O)O)C1CCCN(C(=O)CCC2CCNCC2)C1 +COc1ccc(CCc2cnc3c(N)nc4cc(C=CP(=O)(O)O)ccc4c3c2)c(C)c1 +COc1ccc(N2Cc3cnc(Nc4ccc(F)cc4)nc3N(C3CCC(O)C3)C2=O)cc1 +O=C(CCCN1CCN(c2cccc(Cl)c2)CC1)NCc1nc2ccc(F)cc2c(=O)n1-c1ccccc1 +Nc1cccc(Nc2nc(NCCO)nc(NCCc3ccc(Nc4nc(NCCO)nc(Nc5ccc(F)cc5)n4)cc3)n2)c1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3Br)ccc2[nH]1 +CC(c1ccc(C(=O)NCCC(=O)O)cc1)N1C(=O)C(c2cccc(Cl)c2)=NC12CCC(C(C)(C)C)CC2 +CC(N)(COP(=O)(O)O)c1nc(-c2ccc(OCCc3ccc(-c4ccccc4)cc3)cc2)c[nH]1 +O=C(NCC(NS(=O)(=O)c1ccccc1)P(=O)(O)O)c1ccc(OCCC2CCNCC2)cc1 +FC(F)(F)c1ccc(Nc2ccnc3nc(-c4ncccc4C(F)(F)F)ccc23)nc1 +CN(C)Cc1ccc(-n2cc3cccc(C(N)=O)c3n2)cc1 +CC(C(=O)NC(C#N)CC(N)=O)N(Cc1ccc(-c2cccc(F)c2)cc1)S(C)(=O)=O +Fc1ccc(Br)c(F)c1C1CC(c2cccc(Br)c2)Nc2nnnn21 +O=C(Nc1cc(-c2cc3c([nH]2)C2(CCCNC2)CNC3=O)ccn1)c1ccc(C(F)(F)F)cc1 +Cc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)c(F)c3)(C(F)(F)F)C2)cc1 +COc1ccc(-c2csc(=O)[nH]2)cc1S(=O)(=O)NC1CCCC1 +CCN(CC)CCCC(C)Nc1c2c(nc3ccccc13)CCCC2 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C(C)CNCc1cccn1C +CCCC#CC1(C(F)(F)F)OC(=O)Nc2cccc(F)c21 +COc1cc(C2Nc3ccc(C(=N)N)cc3C3c4ccccc4CC23)ccc1O +COCCOCCOCCOCCOCCOCCOCCOCCOCCOC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CCC2)C1O5 +Oc1cccc(C(Nc2nccs2)c2ccc3cccnc3c2O)c1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2c(C)noc21 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cncc3ccccc23)cc1 +CCCCN(C)c1nc(NCc2ccccc2)c(C(=O)O)c(SCc2ccccc2)n1 +CC(C)CC(C(=O)O)c1cc(C=Cc2ccc(-c3ccccc3)cc2)cc(-c2ccc(Cl)c(C(F)(F)F)c2)c1 +CCCCCNC(=O)NCCCCC=CCCCCCCC(=O)NS(C)(=O)=O +COc1n[nH]c2cc(NC(=O)NC(C)c3cccc(Cl)c3)nc(CO)c12 +CNc1cc2nc(C)c(-c3cc(NC(=O)NCCC(C)(C)F)c(F)cc3C)cc2cn1 +COc1ccccc1C(=O)Nc1ccc2c(c1)CCCN2C(=O)c1ccccc1 +Nc1n[nH]c2cccc(-c3ccc(NC(=O)C4(C(=O)Nc5ccc(Br)cc5OC(F)(F)F)CC4)cc3)c12 +COC(=O)C=C1C(=O)N2C(C(=O)O)=C(COC(C)=O)CS(=O)(=O)C12 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(CC(N)=O)cc3)NC(=O)NC1=O)C2 +COc1ccc(C(=O)Nc2cccnc2)cc1OC1CCCC1 +CNC(=O)c1cccc(Nc2ncnc(N3CC(Oc4cc(Cl)ccc4Cl)C3)n2)c1 +C#CCN(C)C(=O)C=C1c2nc3ccccc3cc2C(=O)N1c1ccc(Cl)cc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(-c4cccc(N5CCSCC5)n4)cc3)NC(=O)NC1=O)C2 +CCC1(C)CN(C(=O)CN2CC(C)NCC2COC)c2cc(Cl)ccc21 +Cc1n[nH]cc1-c1cc2nc(CN3CCC(c4ccccc4)C3)[nH]c(=O)c2s1 +CCOC(=O)c1c(-c2cccc(OC(F)(F)F)c2)[nH]c2cc(OC)ccc2c1=O +Nc1nc(N=NNC(=O)Nc2cccc(Cl)c2)nc2c1ncn2C1OC(CO)C(O)C1O +CC(C)Oc1cc(Oc2cnc(C(=O)N(C)C)c(F)c2)cc(-c2nccc(=O)[nH]2)c1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cccc(N5CCN(CC(N)=O)CC5)c4)nc23)cc1 +COc1cc(-c2cc(F)cc(Cl)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +COc1ccc(-c2nc(-c3cccnc3)oc2Sc2ncccn2)c(OC)c1OC +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(-n4ccnc4)c3)s2)nn1 +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1Cl +Cc1cc(C2CN(Cc3c(C)cccc3F)CC2N(C)C)ccc1C(=O)Nc1ccncc1 +N#Cc1cnc(NC(=O)Nc2ccc(CCNCCc3ccc(F)cc3F)c(Cl)c2)cn1 +CCOC(=O)N1CCC(CNc2nc3c(s2)CCCc2ccc(F)cc2-3)CC1 +COc1ccc2c(c1)c1c(n2S(=O)(=O)c2cccc3ccccc23)CCCC1CN(C)C +COc1ccc(CN(CCCOc2cccc(CC(=O)O)c2)CC(c2ccccc2)c2ccccc2)cc1 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+CCN(CCN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1)C(=O)c1ccc(CN2CCC(C(N)=O)CC2)cc1 +O=C(c1nn(-c2cccc(OCCn3cccn3)c2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +COc1ccccc1Oc1ccc(S(C)(=O)=O)cc1-c1cn(C)c(=O)c2[nH]ccc12 +CC1CN(c2nc(N3CCOCC3)c3sc(-c4ccccn4)cc3n2)CC(C)O1 +CCc1ccc(S(=O)(=O)N=C2C=C(Nc3ccc(O)cc3)C(=O)c3ccccc32)cc1 +O=C(C=Cc1ccc(Sc2ccccc2OCc2c[nH]cn2)c(C(F)(F)F)c1C(F)(F)F)N1CCOCC1 +Cc1nc(NC(C)c2cccc(-c3cnc(N4CCN(C)CC4)nc3)c2)cc(-c2ccc3ncsc3c2)n1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(OC(C(=O)O)c2ccccc2)c(C)c1 +O=C(C1CC(N2CCc3cc([N+](=O)[O-])ccc32)CN1)N1CCSC1 +CCN(CC)C(=O)Cc1c(-c2ccc(OC)cc2)nn2c(C)cc(C)nc12 +Cn1cnc(-c2ccnc(Nc3cc(Cl)c4[nH]c(C(=O)NC5CCCNC5)cc4c3)n2)c1 +O=C1N(Cc2cccc(-c3cccnc3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +COc1ccc(NCCNC(=O)C2(Oc3ccc(C4CCCCC4)cc3)CCCCC2)cc1 +NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CCc1ccc(-c2ncccn2)cc1 +CN1CCN(CCCOc2ccccc2Nc2nc(C#N)nc3c2ncn3C2CCCC2)CC1 +O=C1C(NS(=O)(=O)C=Cc2ccc(Cl)s2)CCN1c1ccc(-n2ccnc2CN2CCC(F)C2)cc1F +O=C1OC2(CN3CCC2CC3)CN1c1ccc2c(c1)OCO2 +CC(Cc1nc2cc(C=CC(=O)NO)ccc2n1CC(C)(C)CN(C)C)CC(C)(C)C +COCc1ncc(Cc2ccc3cccc(N)c3n2)c2cc(OC)c(OC)cc12 +COc1cc(C=CC(=O)OCCc2ccc(O)cc2)ccc1O +CC12CC(=O)C3C(CCC4CC(O)CCC43C)C1CC=C2C#N +CC1CN(Cc2ccccc2)CCN1c1nc(-c2ccncn2)cc(=O)n1C +Cc1cccc(Oc2ccc(C#N)c(C(F)(F)F)c2)c1 +Cc1cc(NC(=O)CC2CCCC2)ccc1N1CCC(N2CCCC2C)C1 +CC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2ccccc12 +Cc1[nH]cnc1CSCCN=C(NC#N)NCCCc1c[nH]cn1 +CC(C)n1cc(C(=O)c2cncc(NC3CCN(C=O)C3c3ccc(F)cc3)n2)c2c(N)ncnc21 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccoc3)n(CC(=O)N3CCC(C(=O)O)CC3)c2c1 +CC1c2cccc(C(N)=O)c2C(=O)N1C1CCN(CC2CCCCC2)CC1 +COc1cc(CC2COC(=O)C2Cc2ccc(O)c(OC)c2)ccc1O +CNC(=O)c1cc(Oc2ccc3[nH]c(Nc4ccccc4Br)nc3c2)ccn1 +CS(=O)(=O)Nc1cnc2ccc(-c3cnc4ccccc4c3)cc2c1Nc1ccc(N2CCNCC2)c(C(F)(F)F)c1 +C#Cc1cc(Cl)cc(N2C(=O)c3ccccc3C2(O)c2ccc3[nH]c(NC(=O)OC)nc3c2)c1C +C[n+]1c2n(c3ccccc31)N=C(c1ccccc1)C[Se]2 +COc1ccc(-c2nc3cnc4ccc(C)cc4n3n2)cc1 +O=C(C=Cc1ccc(O)cc1)CC(=O)C=Cc1cc(O)ccc1[N+](=O)[O-] +OC1(CCCc2ccccc2)CCN(CC2CN(CC3CCCCC3)CC2c2ccccc2)CC1 +COc1cc2ccc3c(OC)c(O)ccc3c2c(OC)c1O +COc1cccc(CCc2nnc(-c3ccc4[nH]cnc4c3)s2)c1Cl +CC(C1=C(CCN2CCCCC2)Cc2ccccc21)c1ccccn1 +COC1C(F)CN(C(=O)Cn2cc(C(C)=O)c3ccccc32)C1C(=O)NC(C)c1cccc(Cl)c1F +COc1ccc(-n2nc(CC(C(=O)O)c3cccc(Cl)c3)cc2-c2ccc(C)cc2)cc1 +CCOC(CC(=O)O)c1ccc(OC2CCCc3ccccc32)cc1 +CC1CN(Cc2ccccc2)c2ccccc2CN1C(=O)NCc1ccccc1 +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CCc3ccccn3)cc2n1 +CC(C)CCN(C(CO)CCCCNC(=O)N(Cc1ccccc1)Cc1cccc2c1OCO2)S(=O)(=O)c1ccc(N)cc1 +c1ccc2c(NCCCCCSc3c4c(nc5ccccc35)CCCC4)c3c(nc2c1)CCCC3 +O=C(NCC(O)CO)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2 +CCCNC(CC1CCCCC1)C(=O)NC(Cc1ccccc1)C(=O)NCc1ccc(CN)cc1 +Cc1cc(CN2CCCC2CO)ccc1C(=O)Cn1ccc(OCc2ccc(Br)cn2)cc1=O +COc1ccc(Cl)cc1S(=O)(=O)c1c[nH]c2ccc(C(=O)Nc3ccc(CC(=O)O)cc3)cc12 +O=C(NC1CCCCC1)c1ccc(S(=O)(=O)NCCc2c(-c3cc4ccccc4o3)[nH]c3ccccc23)cc1 +O=C(NC1c2ccccc2CC1O)C(O)C(O)C(O)C(Oc1ccccc1)C(=O)NC1c2ccccc2CC1O +COc1cc(OC)c(NC(=O)N(c2ccccc2)c2nnn(CCCCCCCCOC3CCCCO3)n2)c(OC)c1 +COCc1nc2c(NC(C3CC3)C3CC3)nc(C)nc2n1-c1ccc(OC)cc1 +O=C(Cc1c[nH]c2cc3ncnc(Nc4cccc(Br)c4)c3cc12)N1CCOCC1 +CCOc1cc(=O)n(C)cc1-c1cc(N(CC2COCCO2)S(=O)(=O)CC)ccc1Oc1ccc(F)cc1F +COc1cc(OC)c(C=CS(=O)(=O)Cc2ccc(OC)c(NC(C(=O)O)C(F)(F)F)c2)c(OC)c1 +C=C(CN1CCOCC1)C(=O)Nc1ccc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1 +Cc1cc(Cl)cc2cc(C(=O)N3CC(N4CCCC4)C3)[nH]c12 +Cc1cc(OCc2ccc(NC(=O)C3CCN(C(=O)c4ccco4)CC3C(=O)NO)cc2)c2ccccc2n1 +CN(CCO)C1CCN(c2nc3ccccc3n2Cc2ccc(F)cc2)CC1 +O=C(O)CCC=CCC1C(F)CCC1NS(=O)(=O)c1ccc(Cl)cc1 +Cc1cccc(N2CC(=O)N3C(Cc4c([nH]c5ccccc45)C3c3ccc4c(c3)OCO4)C2=O)c1 +CCCCCCCCCCCCCCCCOP(=O)(O)OCC1OC(n2cc(C)c(=O)[nH]c2=O)CC1N=[N+]=[N-] +O=C(NC1CCCCCC1)c1cc(C=Cc2ccccc2)cn(Cc2ccc(F)cc2)c1=O +CC1(C)CC(c2cc(C(C)(C)C)c3c(c2)C(C)(C)CO3)=NO1 +Nc1nc(-c2ccccc2)c2c(n1)-c1cc(OCCN3CCCC3)ccc1C2=O +c1cc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)oc3c2)n2nccc2c1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCC(C(=O)c5ccc(Cl)cc5)CC4)nc3n2)cc1CO +CC(=O)NCc1cc(-c2ccc(C=CC(=O)O)cc2)cc(C23CC4CC(CC(C4)C2)C3)c1O +CCCc1c(OCCCCOc2ccc(C(C)(C)C(=O)O)cc2)ccc2c(-c3ccccc3)noc12 +O=C1CN(c2cccc3c2cnn3-c2ccccc2F)CCN1CC(=O)N1CCC(F)C1 +CCCc1c(OCc2cccc(Oc3ccc(-c4nn[nH]n4)cn3)c2)ccc(C(C)=O)c1O +Cc1ccc(N2CCC(N(c3ccc(C(F)(F)F)cc3)c3cccnc3)CC2)cn1 +Brc1ccc(CN2CCN(Cc3ccc4c(c3)OCO4)CC2)cc1 +O=c1nc(OCC2COCCO2)cc2n1CCc1cc(-c3ccc4[nH]ccc4c3)ccc1-2 +CCOC(=O)c1c(NCc2ccc3c(-c4nnn[nH]4)cc4ccccc4c(=O)c3c2)cc(C)nc1C +NC1(c2ccccc2)CC2CCC(C1)N2C(c1ccccc1Cl)c1ccccc1Cl +Nc1ncnc(N2CCC(c3nc(-c4cccc(F)c4)cn3CCN3CCCC3)CC2)c1Br +CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(c2ccccc2)c2nnn[nH]2)cc1 +COc1ccc2c(c1)c(CC(=O)NCCCCO)c(C)n2C(=O)c1ccc(Cl)cc1 +COc1ccc(CC(=O)NC(NC(=NC#N)Nc2c(F)cccc2F)C(C)(C)C)cc1OC +FC(F)(F)c1cc(COCC2(c3ccccc3)CCNCC2)cc(-c2nccs2)c1 +CN(C)C1CCN(c2cnc3ccc(Sc4nnc5c(F)cc(-c6cnn(C)c6)cn45)cc3c2)C1 +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(Cc3ccccc3OC)C2=O)cc1 +COc1ccc(C(=O)N2CCN(c3ccc4[nH]c5nc(O)nc-5cc4c3)CC2)cc1OC +CNc1c(Br)cnc2[nH]c(-c3cnn(C4CCN(C)CC4)c3)nc12 +COc1cc(-n2cnnc2)cc(Cl)c1C(=O)NCC(c1ccccc1)c1nc2cc(C)c(C)cc2[nH]1 +O=C1Cc2cc(-c3cc(Cl)ccc3Oc3cc(F)c(S(=O)(=O)Nc4ncns4)cc3F)ccc2N1 +CCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 +CC(C)S(=O)(=O)n1c(=O)n(Cc2nc3ccccc3n2CCCC#N)c2cnccc21 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3ccccc3)cc2)C(=O)C(C)C)c1 +O=C(Nc1nc2ccc([N+](=O)[O-])cc2s1)c1cccnc1Nc1cc(F)c(F)c(F)c1 +c1ccc(Cn2c(-c3ccc(OCC(CC4CCNCC4)n4c(-c5ccccc5)nc5ccccc54)cc3)nc3ccccc32)cc1 +Cc1c(C(=O)Nc2ccc(-c3ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc3)cc2)oc2cccc(N)c12 +O=C(O)CNc1ccc(-c2cnc(N3CCOCC3)c3nc(C=Cc4ccc5ccccc5n4)cn23)cn1 +O=C(O)c1csc(-n2nc(N3CCCCC3)c3ccccc32)n1 +Cc1cc(N(CCNc2ccnc3cc(Cl)ccc23)Cc2ccco2)nc(Cl)n1 +COc1cccc(CCN2CCC(CCc3ccccc3)CC2)c1 +CN(O)CCCc1ccc2c(c1)C(=O)c1ccccc1CO2 +CC1CCC2C(C)(COC(=O)c3ccco3)OC3OC4(C)CCC1C32OO4 +CCCCCCCCCC(=O)NC(Cc1ccc(C)cc1)C(=O)NC1C=CCCNC(=O)C=CC(C(C)C)NC1=O +COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)cn(C)c1=O)C2=O +COc1ccc(C(=O)Nc2nc(C)nc3cn(-c4ccccc4)nc23)cc1 +COc1ccc(C=C2CC(CO)(COC(=O)CC(C(C)C)C(C)C)OC2=O)cc1 +O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2CNc2ccc(-c3ccc(F)c(Cl)c3)cc2)cn1 +Cc1ccc2[nH]cc(C(=O)OCC34CCN(CC3)CC4)c2c1 +COCCOc1cc2ncnc(NC3=CC(=O)C(SC)=CC3=O)c2cc1OC +O=[N+]([O-])c1cc(CNCP(=O)(O)O)c2nc(O)c(O)nc2c1 +CCc1cn(C2CC(O)C(CNC(=O)Cc3ccccc3-c3ccccc3)O2)c(=O)[nH]c1=O +CS(=O)(=O)c1ccc(-c2cc(C=CCC[N+](=O)[O-])nn2C2CCCCC2)cc1 +Cc1cc(Cc2nc3n(n2)Cc2c(C)ncn2-c2ccccc2-3)on1 +NC(CC(=O)N1CCNCC1Cc1ccccc1)Cc1cc(F)ccc1F +COc1cc(OC)c2c(c1Cl)OC1(C2=O)C(OCc2ccccc2)=CC(=O)CC1C +O=c1ccc(-n2ccc3ccccc32)nn1CCCN1CCN(c2ccccc2Cl)CC1 +CC1(C)OC(=O)Nc2ccc(-c3ccc(C#N)[nH]3)cc21 +CCC1(C)NC(=O)c2cc(S(=O)(=O)Nc3ccc(OC)cc3)ccc2NC1=O +CCC(COc1ccc(C=C2SC(=S)N(CC(=O)O)C2=O)cc1OC(c1ccccc1)C(F)(F)F)c1ccccc1 +Cn1c2ccccc2c2c(NCCCN)nc3ccc(Br)cc3c21 +COc1ccc2c(c1)c1nn(CCOS(C)(=O)=O)c3cc4c(c(c13)n2C)C=CC(C)(C)O4 +CCc1nc2c(C)ccnc2n1C1CCc2cc(-c3ccccc3-c3nn[nH]n3)ccc21 +FC(F)(F)c1ccc2c(c1)nc(N1CCNCC1)c1cccn12 +Cn1cc(C(=O)NCCCO)c(Nc2ccc(I)cc2F)cc1=O +CCCCCCN1CCN(c2nc3ccccc3n2CCOCC)CC1 +Cc1c(C(C)C)c(=O)on1C(=O)N1CCN(c2ccccc2)CC1 +Cc1ccc(C2CC(c3cc(Br)ccc3O)=NN2C(=O)c2ccco2)cc1 +O=C(Nc1ccc2c(c1)OCC(CN1CCCC1)=C2)c1ccc(-c2ccc(F)cc2)cc1 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+C=CC(=O)Nc1cccc(Oc2nccc(Nc3cc(C)[nH]n3)n2)c1 +Cc1nc2sc(C(=O)NC(C)(C)C)c(N)c2c(C)c1Cl +O=c1ccoc2cc(OCCCN3CCN(CCCNc4c5c(nc6ccccc46)CCCC5)CC3)cc(O)c12 +O=C(c1cccc(O)c1)c1ccc(-c2cc(Cl)c(O)c(Cl)c2)s1 +COc1ccc(-c2cnc(N)nc2-c2ccccc2O)cc1C +Cc1cccc(NC(=O)Nc2ccc(Oc3ccnc(-c4cc(C(=O)N5CCCC(O)C5)c[nH]4)c3)cc2F)c1 +NC(CC(=O)N1CCn2nnc(-c3ccncc3)c2C1)Cc1cc(F)c(F)cc1F +Cc1cc(C)cc(C(=O)N2CCC(NCc3ccnc4ccccc34)CC2Cc2ccc3ccccc3c2)c1 +CC(C)C(O)CC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2cc(O)ccc2[nH]1 +COc1cc(Nc2cc(C)nc3ccc(NC(=O)Nc4ccc(N(CCCl)CCCl)cc4)cc23)cc(OC)c1OC +Cc1cc(S(=O)(=O)NCCN(C)C)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +COc1ccc(-c2cc3c(C)nc(N)nc3n(C3CC(OCCO)C3)c2=O)cn1 +CC1CC(C)CN(c2cc(NC(C)C(Cc3ccc(Cl)cc3)c3cccc(Br)c3)ncn2)C1 +CN(NC(=O)CC(=O)NN(C)C(=S)c1ccc2ncccc2c1)C(=S)c1ccc2ncccc2c1 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(-c4ccccc4Cl)no3)ccc21 +CC(C)=CCCC(C)=CCCC(C)=CCCC1(C)CCc2c3c(cc(C)c2O1)OCN(CCCCCCCCO)C3 +Fc1ccc(COCC2CCN(Cc3ccc(-c4ccccc4)cc3)CC2)cc1 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+O=c1n(CCc2ccc3ccccc3n2)nc2cccc(N3CCOCC3)n12 +FC(F)(F)c1cnc(Nc2nc(N3CCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cn1 +Cc1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O +Cc1c[nH]c2ncc(-c3cc(C4CCOCC4)n(C4CC(F)(F)C4)n3)cc12 +CSC1C(C)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)CC1N +COC(=O)CCCC=C(c1cc(C)c(OC)c(C(=O)OC)c1)c1cc(Cl)c(OC)c(C(=O)OC)c1 +O=C(NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(c2ccccc2CNCCCN2CCCC2=O)CC1)C1Cc2ccccc2CN1 +O=C(O)C(Cc1cscn1)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc(Cl)c(Cl)c3)n[nH]c2C1(C)C +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(C3C=CC(=O)N=C3)nc2n1 +CC(C)N1CCN(C(=O)c2ccc3[nH]cc(CN4CCOCC4)c3c2)CC1 +C=C(c1cc(Cl)c(Cl)cc1OCC(O)CNC(C)C)n1ccnc1 +O=CN1CCN(c2cc(-c3ccc(Sc4ccc5c(c4)OCCO5)c(C(F)(F)F)c3)ccn2)CC1 +COc1ccc(NC(=O)c2ccc(F)c(Nc3ncnc4cnc(N5CCN(CC6CC6)CC5)nc34)c2)cc1C(F)(F)F +COc1ccc(CC(=O)O)cc1-c1ccc(S(C)(=O)=O)c2c1CN(C(=O)OCc1ccccc1)CC2 +COc1ccc(C2C3c4c(c5ccccc5[nH]c4=O)OC(C)(C)C3C2C2CC2)cc1OCCCO +CCc1onc(-c2ccccc2Cl)c1C(=O)N(CC)c1ccc(Cl)cc1 +CCc1cc(CN2CCC(C(=O)NC(C)(C)C)CC2)cc(NC(=O)c2cncc(C)c2)c1 +Cc1c(CC(=O)O)c2cccnc2n1Cc1ccc(S(C)(=O)=O)c(C(F)(F)F)c1 +Cc1noc(=O)c2ccc(NC(=O)C(O)(Cc3ccccc3)CC(C)(C)c3cc(F)ccc3O)cc12 +CCCC(NC(=O)CCc1cc(F)cc(F)c1)C(=O)Nc1ncc(C(C)CCCC(C)(C)OC)s1 +Cc1nc2ccccc2c(=O)n1N=Cc1ccc(O)cc1O +CCCCN1C(=O)C(=CNC(C)(C)CO)C(=O)c2cccc(C)c21 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1C +O=C(Nc1cc2cccnc2cc1OC1CCNCC1)c1cnn2cccnc12 +O=C(c1cccc2occc12)c1cn(CCN2CCOCC2)c2ccccc12 +COc1ccc(S(=O)(=O)c2cc(C)c3ncc(C(N)=O)c(Nc4cccc(OC)c4)c3c2)cc1 +CC(C)c1ccccc1Sc1ccc(-c2ccnc(N3CCN(C=O)CC3)c2)cc1C(F)(F)F +O=c1[nH]c(CCCCCCCCCCCCc2nsc(=O)[nH]2)ns1 +CCNC(=O)Nc1ccc(-c2cc(N3CCOCC3C)c3ncn(COCCOC)c3n2)cc1 +COC(=O)c1cc(OC)cc(OC)c1C1CC12C(=O)Nc1ccc(Cl)cc12 +CC(C)CC(NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1)C(N)=O +Cn1c(CC(=O)N2CC(C)(C)c3c(F)cccc32)nc(N2CCOCC2)cc1=O +CNC(=O)c1cn(C)c2c1CCc1cnc(NC3CCN(S(=O)(=O)c4ccccc4)CC3)nc1-2 +CCCCCOC(=O)CCC(=O)Nc1nnc(S(N)(=O)=O)s1 +O=C(NCc1ccc(S(=O)(=O)c2cccnc2)cc1)c1cc2cnccc2[nH]1 +CC(=Cc1cc(F)c(Oc2ccc(S(=O)(=O)NCCOCCOCCOCCN)cc2)c(F)c1)C(=O)N=C(N)N +Cc1c(C(C)C)c(=O)on1C(=O)N(C)c1ccccc1 +COc1cc(-c2onc3c2CCCN3Cc2cc(F)cc(F)c2)ccc1-n1cnc(C)c1 +O=C(NC(Cc1ccc(NC(=O)c2ccnc3ccccc23)cc1)C(=O)O)c1ccccc1Br +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4cccnc4)nc23)N1 +O=C(N1CCC(F)CC1)N1CC(OC(c2ccc(Cl)cc2)c2cccnc2Cl)C1 +COc1cccc(-c2c(C(=O)N[n+]3c(C)cc(C)cc3C)[nH]c3ccc(S(N)(=O)=O)cc23)c1 +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OCC(CO)c6ccccc6)ccn5)n4)ccc3[nH]2)CC1 +N#Cc1cc(-c2ccnc(Nc3cnn(C4CCC(O)CC4)c3)n2)ccc1OCC1CCC1 +C[S+]([O-])c1ccc(-c2cnn3ccc(-c4cccc(S(=O)(=O)C5CC5)c4)cc23)cc1 +O=C(Cc1cccc(OC(F)(F)F)c1Cl)NC1COc2ncccc21 +O=C(NC1CCCCC1O)c1cnc(OCC2CC2)c(-c2ccc(Cl)c(Cl)c2)c1 +COc1ccc(S(=O)(=O)C(CCCC(=O)N2CCCc3ccccc32)CC(=O)NO)cc1OC +CCCCNC(=O)C(C)CC(O)C(N)CC(Cc1ccc(OC)c(OCCOC)c1)C(C)C +COc1cccc(C(C)=NNc2ncc(Cl)c(Nc3cccc(NC(=O)C=CCN(C)C)c3)n2)c1 +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(F)c3)cn2CCN2CCCC2)CC1 +O=C(CCCCCCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1)NO 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+O=C(O)CN(CCOc1ccc([N+](=O)[O-])cc1)CCc1ccc([N+](=O)[O-])cc1 +Oc1ccc(-c2ccc3c(c2)OCO3)cc1CNCC1(N2CCCCC2)CCCCC1 +CN(CCCCCCCCCOc1ccc2c(=O)c3ccccc3oc2c1)Cc1ccccc1 +COc1cc(-c2nnc(-c3ccc(O)cc3O)s2)cc(OC)c1OC +CCN(CC)CCCC(C)Nc1nc2ccccc2c2c1c1ccccc1n2C +COc1cc(O)cc2c1C(Br)=C(c1ccc(O)cc1)C2=O +CC(=O)N1CCN(c2ccc3cc2COCC=CCOCc2cccc(c2)-c2ccnc(n2)N3)CC1 +CC1C(c2ccccc2)C1(NS(=O)(=O)N1CCN(c2ccc(Cl)cc2)C(CO)C1)C(=O)O +CN1CCCC(CC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cccnc43)CC2)C1 +CCn1c(=O)ccc2c(-c3cnc(-c4cccnc4)s3)n[nH]c21 +COc1cccc(OC)c1-c1cc(C(=O)NC(C(=O)O)C2CCCCC2)nn1-c1ccnc2cc(Cl)ccc12 +N#CC1(C(=O)N2CC(CF)C(Nc3c(C(N)=O)cnn4cc(-c5cnn(C6CC6)c5)nc34)C2)CC1 +Cc1ccc(N(C(=O)NCCCN2CCC3(CCc4ccccc43)CC2)c2cccc(F)c2)cc1 +Cn1c(=NNC(=O)c2ccco2)sc2cc(OC(F)(F)F)ccc21 +COc1ccccc1N1CCN(CCCCn2cc(-c3ccc(N)cc3)nn2)CC1 +COc1cccc(-c2c(C)n(Cc3ccccc3F)c3nc(C(C)(C)C)c(CN(C)CCc4ccccc4)n3c2=O)c1 +Cc1ccc(NC(=O)c2ccc(CN3CCN(CCO)CC3)cc2)cc1-n1cc(-c2cccnc2)cn1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNCc2cccc(I)c2)c1 +CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccccc5)CC4)cc3)cc2n(CC)c1=O +c1cc2c(ncn3nnc(C4CCC(CNCC5CCCO5)CC4)c23)[nH]1 +OC(CN1C2CCC1CC(c1ccccc1)C2)c1cccc(Br)c1 +Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)noc1C1=CCCCCC1 +O=c1c2ccccc2ncn1CCCCN1CCN(c2ccc(Cl)cc2)CC1 +CC(NC(=O)C1(NC(=O)C(F)(F)F)CC1)c1ccc(-c2cccc(Cl)c2-c2nnn(C)n2)cc1F +NS(=O)(=O)Nc1ccc(S(=O)(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1cc(C#N)cnc1C(=O)Nc1ccc(F)c(C2(C(F)F)COCC(N)=N2)c1 +CC(C)(C)CCC1(C(=O)c2cc(Cl)c(Cl)s2)CCNC1 +C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(OCCOC)cc23)c1 +CCCN(Cc1sc(Nc2c(Br)cc(Br)cc2Br)nc1C(F)(F)F)CC1CC1 +CCCCCCCCCCCCCC(=O)OC12C(O)C(C)C3(O)C(C=C(CO)CC4(O)C(=O)C(C)=CC43)C1C2(C)C +CCc1cccc(N(C)C(=N)Nc2cc(SC)cc(Br)c2Cl)c1 +Fc1ccc(Cc2nnc3ncc(-c4cccs4)nn23)cc1 +CN1C2CCC1CC(N(c1ccccc1)c1ccc(C(=O)O)cc1)C2 +CNc1nc(Nc2cc(OC)c(C(=O)N3CCCC3)cc2Cl)ncc1Cl +Nc1nc(NCC(O)c2ccccc2)nc2c1ncn2C1OC(CO)C(O)C1O +CCS(=O)(=O)c1ccc2[nH]c(Oc3cccc(-c4ccccc4)c3)nc2c1 +Cn1ncc2cc(-c3nn(C(C)(C)C)c4ncnc(N)c34)ccc21 +Cc1ccc(CN2C(=O)N(Cc3ccc(C)cc3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)cc1 +CC(C)(C)c1ccc(-n2cc(-c3ccc(S(N)(=O)=O)s3)nn2)cc1 +O=C(Nc1ccc(C(F)(F)F)cc1Cl)N1CCC2(CCc3cccc(Cl)c3O2)CC1 +CCNc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(CO)c12 +Cc1c(Cc2ccccc2Cn2ccnn2)c2c(n1CC(=O)O)CCNC2=O +Cc1sc(-c2ccc3c(c2)OCO3)nc1CCOc1ccc2c(c1)CCC2CC(=O)O +COc1ccccc1N1CCN(CCCCC(Oc2ccc(C(=O)Nc3ccccc3OCCCC(=O)O)cc2)c2ccccc2)CC1 +NCc1ccc(C(=O)NCC(=O)N2CCN(CC(=O)O)C(=O)C2CC(=O)O)cc1 +COc1cccc(C(=O)N=c2sc(C(C)(C)C)c(C)n2CC2CC2)c1 +O=C(CN1CCCCC1)Nc1cnc2c(c1)nc(O)c1ccccc12 +Cc1cc(-c2n[nH]c3cc(NC(=O)N4CCN(c5ccc(F)cc5)CC4C)ncc23)ccn1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(OCC(C)C)c2)c1 +CC1CN(c2sc(C(F)(F)F)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cc(C2CCN(C)CC2)cn1 +O=C(c1ccc(F)cc1-c1ncccn1)N1C2CCC1C(Nc1ccc(C(F)(F)F)cn1)C2 +O=C(O)c1ccc(-c2c(C#Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)s1 +COc1ccc(N=c2oc3cc(O)ccc3cc2C(=O)NCCCO)cc1 +Fc1ccc(-n2cc(CCCCN3CCC4(CC3)OCc3c(F)cccc34)c3ccccc32)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)C4CCCC4)ncc3Cl)C2)cc1 +O=c1[nH]c(N2CCC(N3CC=C(c4ccccc4)CC3)CC2)nc2ccccc12 +CN(C)C1Cc2ccc(O)c3c2C2C(O3)C(=O)CCC21O +Cc1cc2nc(C3CCOC3)n(-c3ccc4c(N)nc(N)nc4c3)c2cc1C +Fc1ccccc1-c1n[nH]c2cnc(-c3cnccc3OCC3CCCNC3)cc12 +CCN(C(=O)c1ccccc1)c1ccnc(NC(C)c2ccccc2)n1 +NC(=O)C1(c2ccccc2CCc2nc(Nc3cnn(C4CCNC4)c3)ncc2Cl)CC1 +Cc1cc(C2CCCN(C(=O)c3ccc4ccccc4c3)C2)n2ncnc2n1 +Cc1[nH]c(Br)c(C)c1-c1ccnc(Nc2ccc(F)cc2)n1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2cnc3ccccc3c2)n1 +Nc1ccc2[nH]c(C(=O)NCc3ccc(C(=O)Nc4ccccc4N)cc3)cc2c1 +CC(C)=CCN(Cc1cc2c(=O)n(C)c(C)nc2cc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +CCc1cc(CC)nc(OCCCn2c3c(c4cc([N+](=O)[O-])ccc42)CCCC3)n1 +CCCCc1nc(-c2nc(C)c[n+]([O-])c2C)cn1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c(-c3cccs3)nn(CCC3CCC3)c1=O)N2 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(OC(F)(F)F)c1 +CN1CCc2nc(C(=O)Nc3ccc(C(=O)O)cc3CNC(=O)c3ccc(Cl)s3)sc2C1 +Nc1nc(C=Cc2ccccc2)nc2cn(-c3ccccc3)nc12 +CCC(N)C(=O)NC1CCCCC2CCC(C(=O)NC(c3ccccc3)c3ccccc3)N2C1=O +CCc1ccc(NC(=O)Nc2cc(C(C)(C)C)sc2C(=O)NC)cc1 +O=C(O)COCC1CCC(COC(=O)N(c2ccccc2)c2cccc(Cl)c2)CC1 +CCCCC(NC(=O)c1ccc(CN=C(N)N)cc1)C(=O)NC(CC(C)C)C(=O)NC1CCCCC1c1cccc(Cl)c1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)ncnc1OCC#CCO +CCOC(=O)CCc1ccc(-c2ccc(OC)cc2)n1-c1ccc(C(=O)NCCO)cc1C +CC(C)C(NC(=O)c1cccnc1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)C2(CC2)C1 +COc1cncc(C2=CCC3C4CCN5C(=O)CCCCC5(C)C4CCC23C)c1 +N#Cc1ccc(OCCCN2CCC(C(O)(c3nccs3)C3CCCC3)CC2)cc1 +Nc1ccc(Nc2cc(=O)oc3c2ccc2ccccc23)cc1 +Cc1ccc(S(=O)(=O)N(C)C(C)(C)C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)cc1Cl +CC1=CCC2C(C1)c1c(O)cc(CC=CCCCO)cc1OC2(C)C +CC1(C)CC(O)CC(C)(CNc2cc(Cl)cc(C(F)(F)F)c2)C1 +CC(C)c1[nH]nc2c1C(c1cccnc1OCC(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O +COc1cc(OCc2nc(-c3ccnc(F)c3)sc2C)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +COc1ccc2ccn(CCn3cc(NC(=O)c4ncoc4-c4cccc(C)c4)cn3)c2n1 +CCOc1cc(C=C(C#N)c2nc3ccccc3[nH]2)ccc1OCc1ccccc1C#N +CSc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 +CN(C)CCN(C)Cc1ccc2n1Cc1ccccc1N(C(=O)c1ccc(NC(=O)c3ccccc3-c3ccccc3)cc1Cl)C2 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+Cc1cc2c(cc1C(=O)N=C(N)N)S(=O)(=O)CCC2 +CONC(=O)c1ccc(F)c2c(C(=O)C(=O)N3CCN(C(=O)c4ccccc4)CC3)c[nH]c12 +COc1cccc(Nc2ccc(NC(=O)C3CC3)cc2)c1 +C=CCCCCCCC(OC(=O)N(CCCCC=C)CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)c1ccccc1 +Cc1cccc(NC(=O)NC2CC(c3ccccc3C)CC(c3ccccc3)N(CC(=O)Nc3ccccc3Cl)C2=O)c1 +N#CCc1cccc(C#Cc2ccc(CCC(=O)O)cc2)c1 +Cc1ccc(C(NC(=O)c2ccccc2O)C(=O)Nc2c(C)cccc2C)s1 +O=C(Cc1ccc(Br)cc1)NC(CCS)C(=O)NC(Cc1ccccc1)C(=O)O +CCCCN(C)c1ncc(-c2ccccn2)c(NC2CCC(O)CC2)n1 +COc1ccc(CN2CCC(n3c(O)nc4ccccc43)CC2)c(Cl)c1 +CN1CCCN(c2c3cc(Cl)ccc3nc3c2c2ccccc2n3C)CC1 +CCCCc1nc(Cl)c(COC)n1Cc1ccc(NC(=O)c2ccccc2S(=O)(=O)O)cc1 +COc1cccc(-c2cc(-n3cc(CNCC(C)C)c4ccccc43)c(C)cn2)c1 +O=C(Nc1nc2cc(Br)ccc2[nH]1)c1cc2ccc(Br)cc2[nH]1 +COc1cc(Cc2cnc(N)nc2N)cc(OCCCC(=O)O)c1Br +COCc1cc2cc(c1)C(=O)NC(C(O)CNC(C)(C)c1cccc(C(C)C)c1)Cc1cccc(c1)OCCCCN2 +COc1ccc(-c2ccc(Cl)c(C(=O)CC(=O)C(=O)O)c2)cc1 +C#CCn1c(-c2ccccc2)nc2sc3c(c2c1=O)CCC3 +O=C(NCCc1ccc(Cl)cc1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CN1CCN(c2ccc3[nH]c(-c4c(N)c5cc(C(=O)NCc6ccccc6)ccc5[nH]c4=O)nc3c2)CC1 +CCOC(=O)c1c(N(CC)Cc2ccccc2)nc2ccccc2c1-c1ccccc1 +O=C1CC(CCc2ccccc2)(c2ccccc2)OC(O)=C1Sc1ccccc1C1CCCCC1 +CC(C)c1ccc(Cc2cc(C(=O)C(=O)Nc3cccnc3)c3ccccn23)cc1 +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5cncn5c4)c3c2)C1 +CCc1cc2cnc(Nc3ccc(N4CCC(O)CC4)cn3)nc2n(C2CCCC2)c1=O +CCCn1c(=O)[nH]c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(Br)cc4)cc3)cc21 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(-n3ccnc3)cc2)cc1 +N=C(N)N1CCCC1Cc1nc(-c2ccc(Nc3nc(-c4cccc(C(F)(F)F)c4)cs3)cc2)no1 +CCC(CO)Nc1nc(NCc2cccc(O)c2)c2ncn(C(C)C)c2n1 +COc1ccccc1N1CCN(CCNC(=O)C2CC3CCCC3C2)CC1 +CCc1ccnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4ccnc(N)c34)cc2)c1 +COc1ncccc1-c1csc2ncnc(N3C4CCC3CC(NC3CCC3)C4)c12 +Cc1cc(NCP(=O)(O)O)cc(C)c1Cc1ccc(O)c(C(C)C)c1 +CCCNC(=O)N1C(C#N)C(c2ccc(C#Cc3ccc(F)cc3)cc2)C1CO +O=C(NCc1ccno1)c1csc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)n1 +COc1ccc(Oc2cccc(C(CC(=O)NO)S(=O)(=O)c3ccc(OC)c(OC4CCCC4)c3)c2)cc1 +CC(C)n1nc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)c2cc(OCc3ccccc3)ccc21 +COc1ccc(NC(=O)Nc2ccc(-c3cccc4onc(N)c34)cc2)cc1Cl +O=C(Nc1c(Cl)cccc1Cl)NC1CCC(Oc2ccc(F)cc2)CC1 +O=C(Nc1ccccc1)c1ccc([N+](=O)[O-])o1 +O=C1CN(C2CCCc3c(OCc4ccncc4)cccc32)C(=O)N1C1CCCCC1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CCC2)C1c1ccc(C#N)cc1-c1ccco1 +COC1C(OC(N)=O)CCC2(CO2)C1C(C)=CCC=C(C)C +O=C1CCc2ccc(OCC#CCN3CCN(c4cccc(Cl)c4Cl)CC3)cc2N1 +COc1ccc(CNC(=O)c2ccc3c(c2)c(C)c(C)n3Cc2ccc(-c3ccccc3C(=O)O)cc2)cc1 +CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OC(=O)CN +Cc1cc(CC2CNCC2NCCNCCc2cccc(F)c2)cc(N)n1 +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)NC(C)C)c1ccc(Br)s1 +Cc1nc(N2CC3C(=O)N(C)C(N)=NC3(c3cccc(C#N)c3)C2)nc(C2CC2)c1F +O=C1CC2CCCC3(CC(CC(CCCCc4ccccc4)O3)OC(=O)CC(CO)O1)O2 +O=C(CCc1c[nH]c2ccccc12)N1CC2CCCN2CC1Cc1ccccc1 +Cc1[nH]c2ccccc2c1Cc1ccc(C(=O)NC2CNCC2C(=O)NO)cc1 +O=C(Cc1ccccc1Cl)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 +CC(C)Nc1c(C(N)=O)cnc2cc(-c3ccc(S(C)(=O)=O)cc3)ccc12 +COc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(C3CCC(O)CC3)sc2c1 +COc1cn(-c2ccc3c(c2F)C(C)(C)C(=O)N3C)nc(-c2ccnn2-c2ccccc2)c1=O +Cn1c(N2CCOCC2)cc(OCc2cc(F)c(Oc3ccc(Cl)c(C(F)(F)F)c3)c(F)c2)nc1=O +CON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(C)cccc3C)CC2)CC1 +COc1cc(CC#Cc2cnc(N)nc2N)cc(OC)c1OC +CN(C)c1cccc(OCCCn2cnc(-c3ccccc3)c2)c1NC(=O)NC1CCCC1 +COc1ccc(C2CCN3C(=O)OCC23)cc1OC1CCCC1 +Cc1c(Cn2ncc(N3CCNCC3)cc2=O)cccc1NC(=O)c1ccc(-c2ccccc2)cc1 +O=C(O)c1cccc2nc(-c3c(F)c(F)c(-c4cccc(OCc5ccccc5)c4)c(F)c3F)[nH]c12 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCCC4)ncn3)c2c1 +c1n[nH]cc1-c1cnc2ncc(-c3cn[nH]c3)n2c1 +CC1(C)CN(c2ccc(C#Cc3ccccc3)cn2)C(=O)CO1 +O=C(C(=O)N1CCCC1C(=O)OCCCc1ccccc1)C1CCCCC1 +CCNC(=O)c1cn2ncnc(Nc3cc(C(=O)NC4CCC4)ccc3C)c2c1C +O=c1[nH]c(Cc2ccccc2-c2noc(C(F)(F)F)n2)nc2c1cnn2C1CCOCC1 +COC(=O)Nc1ccc2c(c1)NC(=O)C(C)CCCC(N1CCC(c3cncc(Cl)c3)=CC1=O)c1cc-2ccn1 +CC(C)(C)C(=O)Nc1ccc(N2CCN(C(=O)c3cccc(F)c3)CC2)c(Cl)c1 +COc1cc(-c2ccc3ncc(C(C)=O)c(Nc4cccc(CCN(C)C)c4)c3c2)cc(Cl)c1O +Cc1ccccc1S(=O)(=O)N(C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CCOc1ccccc1-c1nc(O)c2nc3cccc(CC)n3c2n1 +CC1=CC(=O)C(O)C2(C)C1CC1OC(=O)C(OC(=O)CC3(O)CCC3)C3C(C)C(O)C4(O)OCC13C42 +COc1ccc(-n2c(S)nnc2-c2csc(NC(=S)Nc3ccccc3)n2)c(OC)c1 +CC1CN(Cc2c[nH]nc2-c2cc(C(=O)NCCO)c[nH]2)CCN1c1ccc(C(F)(F)F)cn1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C(C)C)nc1Cl +COc1ccc(CCCN2CCN(C)CC2)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12 +CCOC(=O)c1ccc(NC(=O)CCc2nc(-c3ccccc3Cl)no2)cc1 +CC1(C)CCN(c2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)c2ccccc21 +Cn1c(=O)ccc2c(NC(=O)NC3CC(CF)(CF)Oc4c(F)cccc43)cccc21 +Cn1cnc2cc(-c3ccc(C(C)(C)N)cc3)nc(N3CCC(CO)C3)c2c1=O +CN(C)C1CCC(n2cc(C(N)=O)c(Nc3ccc(OC(F)(F)F)cc3)n2)C(C#N)C1 +NC1CCCN(c2ccccc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)C1 +COc1n[nH]c2c(F)c(NC(=O)NC(C)c3ccccc3)ncc12 +CC(O)CNc1nc(NCc2ccc3c(c2)OCO3)c2nc(NCC(C)O)nc(NCc3ccc4c(c3)OCO4)c2n1 +Cc1ccc(S(=O)(=O)Nc2ccc(CN3CCN(C(=O)c4cccc(C#N)c4)CC3)cc2)cc1 +CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc4c(C(=O)NC5CCC5)cccc4c3)n2)c1 +CC(Nc1nc(Cl)cc(N2C(=O)OCC2C(C)O)n1)c1ccc(C(C)(C)F)cc1F +CC1(c2nc(NC(=O)c3ncc(OCF)cc3Cl)ccc2F)N=C(N)OCC1(F)F +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)Nc3c(F)cccc3F)nc12 +COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2C(C)C)c1 +NCCNC(=O)Cc1ccc(NC(=O)Cc2ccc(Nc3ncnc4c3ncn4C3OC(CO)C(O)C3O)cc2)cc1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccc(NS(=O)(=O)O)cc3)o2)C(C)O)c(C)c1Cl +COc1cc2c(cc1OC)-c1c(-c3cnc(N4CCOCC4)s3)ncn1CC2 +CC(NC(=O)C1C(C(=O)NCCCCN2CCCC2)C2C=CC1C21CC1)c1ccc(Br)cc1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)cc2c3cccc(C=O)c3nc-2c1O)C(=O)C(F)(F)F +COc1ccc(Br)cc1C(O)C(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)C(C)C +CCOc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +CCN(CCCc1ccccc1)CCC(O)(P(=O)(O)O)P(=O)(O)O +Cc1nc(C#Cc2cncc(-c3cccc(C#N)c3)c2)cs1 +CN1CCCC1COc1ccc(C(F)(F)F)cc1C(=S)N=c1sc(C(C)(C)C)cn1CC1CCCO1 +CCCCCCCCCCCCCCCC(=O)C1=C(O)C(CO)OC1=O +Cn1cc(-c2cnc3ccc(N(CC4CC4)c4cccc(C#N)c4)cc3n2)cn1 +OC1COCC1Nc1nc(Nc2cc(Cl)cc(Cl)c2)ncc1-c1cccnc1 +CCc1sc(NN=Cc2ccccc2C(=O)O)nc1-c1ccccc1Cl +C=CC=CC(C)C(OC(N)=O)C(C)C(O)C(C)CC(C)=CC(C)C(O)C(C)C=CCCc1sccc1C +CC1OC(=O)C2CC3CC(O)CCC3C(C=Cc3ccc(-c4cccc(Cl)c4)cn3)C12 +COc1ccc(C2=C(C(=O)O)C(c3ccc(OC)cc3OC)Oc3ccc(OC(C)C)cc32)cc1 +CN(CC1CCCCN1C(=O)Cc1ccc2c(c1)CCCC2=O)C1CCCC1 +Cc1ccc(-c2cccc3c(=O)n(-c4ccc(N5CC(C)OC(C)C5)nc4)cnc23)cc1 +COc1ccc(OCC(O)CN2CCN(c3ccccc3C)CC2)c(C(C)=O)c1 +CCc1c(Sc2ccccc2)n(CC=Cc2ccc([N+](=O)[O-])s2)c(=O)[nH]c1=O +COC(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2C2CCN(c3ccccn3)CC2)C1 +Cc1nnsc1C1=NNC(=O)C1=Cc1cn(C)c2ccc(F)cc12 +CC(C)CC(N)C(=O)N1CCc2nc(Cc3ccc(F)cc3Cl)sc2C1 +CN(C)CCNC(C(=O)NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccs1 +Cc1nc(NC2CCOc3ccccc32)cc(-c2ccc3occ(C)c3c2)n1 +O=C(NO)c1cc2c(s1)CCN(C(=O)C1CCCCC1)C2 +Cc1cccc2c(OCc3ccccn3)nn3c(-c4ccccc4)nnc3c12 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Cc3ccc(F)cc3F)c(F)c2)CC1 +COc1cc(-c2nn(C3CCC(N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)Nc1ccccc1 +CC(C)(C)OC(=O)NCCCNC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +O=C(c1cc2ccc(O)cc2[nH]1)N1CCC(CCc2ccccc2)CC1 +O=C(NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1)C(O)C(F)(F)F +O=C(O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2ncccc12 +O=c1c(F)cc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2n1C1CCCC1 +CN(CC(CCN1CCCC(n2c(O)nc3ccccc32)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +COCCOc1ccc2cc1CN(C)CC=CCCOc1cccc(c1)-c1ccnc(n1)N2 +Cn1c(-c2ccc(-n3ccnc3C(F)(F)F)cc2Cl)nnc1C1(c2ccc(Cl)cc2)CCC1 +CC(C)=CCn1c2c(ccc1=O)C(NCCc1ccc(Cl)cc1Cl)CCC2 +COc1ccc(-n2cc(-c3ccc4c(c3)C(=O)NCCO4)c(N)n2)cc1 +CCCc1c(OC)ccc2c(-c3cnc(-c4ccc(C(=O)O)c(F)c4)s3)n[nH]c12 +CCCCCC1=NN(C(=O)c2cccc3ccccc23)CC1c1ccccc1 +CN(C)Cc1ccc(CSCCCCSCc2ccc(CN(C)C)o2)o1 +CC(C)(C)c1nc2c(s1)CCc1nc(NC(=O)N3CCC4CC43C(N)=O)sc1-2 +CP(C)(=O)c1ccc(Nc2nc(C3CCCC3)nc3c2ncn3CCc2cccc(O)c2)cc1 +NS(=O)(=O)c1ccc(Nc2nccc(Nc3c(Cl)ccc4c3OCO4)n2)cc1 +CC(C)(C)S(=O)(=O)NCC1CCC(Nc2nc(-c3ccc(F)cn3)no2)CC1 +COC(=O)C1=C(CN2CCOCC2(C)C(=O)O)NC(c2nccs2)=NC1c1ccc(F)cc1Cl +CCCCCn1c2ccccc2c2cc(C(=O)N3CCCCC3)ncc21 +CN1C(=O)C2C(N=C(N3CCCC(N)C3)N2Cc2ccccc2)N(C)C1=O +COC(=O)N1CC2Cc3[nH]ncc3C(C1)N2S(=O)(=O)c1ccc(Cl)cc1 +c1cncc(-c2nc(NC3CC4CCC3C4)c3ccccc3n2)c1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-c2ccccc2)c1 +Cc1cn(C2CC(N=[N+]=[N-])C(COP(=O)(O)OCCOc3cccc4ccccc34)O2)c(=O)[nH]c1=O +COCc1cc(F)ccc1C1CCCn2nc(C=Cc3ccc(-n4cnc(C)c4)c(OC)c3)nc21 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OCC1CN(C)CCO1 +C#CCN1C(=O)C(C)(C)c2cc(-c3ccc(C#N)n3C)cc(F)c21 +CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2cc(F)cc(C(F)(F)F)c2)CC1 +CCCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)OCC3)cc1 +COc1ccc(C(=O)c2ccc(=O)n(-c3ccccc3C)c2)c(OCc2cn(Cc3ccc(Cl)cc3)nn2)c1 +CC1(C)C(=O)N(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c21 +O=c1c(Br)cn(C2OC(CO)C(O)C2O)c(=O)n1CCCCCCCCP(=O)(O)O +CNc1ccc(-c2cc3ncn(C)c(=O)c3c(NCCCO)n2)cc1S(C)(=O)=O +CC(=O)NCCNc1nc(-c2ccccn2)nc2c1CN(Cc1ccc(F)cc1)CC2 +Cc1cnc(C(CC(=O)O)c2cc(Cl)cc(-c3ccccc3OC(F)(F)F)c2)s1 +N=C(N)c1ccc(COc2c(Br)cc(C(=N)N)cc2Br)cc1 +CNc1cc(N2CCCNCC2)ccc1S(=O)(=O)c1cccc(F)c1 +Cc1c2ccnc(C(=O)NCCN(C)C)c2cc2c3cc(OC(=O)CC(C)(C)CC(=O)O)ccc3n(C)c12 +CC(C)Nc1ncnc2c1ncn2C1OC(COS(=O)(=O)NC(=O)c2ccccc2O)C(O)C1O 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+O=C1C=C(OCc2ccccc2)C(O)(Cc2ccccc2)N1CCCNc1ccnc2cc(Cl)ccc12 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3C(=O)OC(C)C)c1C +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3cc(Cc4ccccc4)on3)CC2)C(c2ccccc2)C1 +CC1CN(c2ccc3c(N4CC(C)NC(C)C4)c(C#N)c4nc5ccccc5n4c3c2)CC(C)N1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)NCc3cccc(F)c3)[nH]c12 +C=C(c1ccc(CC)cc1)C1CNC(C(=O)O)C1CC(=O)O +CCN(C(=O)c1cccnc1C(=O)O)C1CC(C)S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +O=C(N1CCCCC1Cc1ccccc1)n1cc(-c2ccc(-c3ccccc3)cc2)nn1 +Cc1cc(-c2ccc(F)c(C)c2)c(CCP(=O)(O)CC(O)CC(=O)O)c(C(C)C)c1 +Cn1cc(NC(=O)c2ccc3cnc(NC4CCCCNC4)nn23)c(C(F)F)n1 +Cn1c(-c2ccccn2)c(C2CCCCC2)c2ccc(C(=O)NC(C)(C)C(=O)Nc3ccc(C=CC(=O)O)cc3)cc21 +Cc1ccn2nc(SCc3nc(-c4ccccc4)cn3C)nc2c1 +Cc1cc(C)[n+](CC(=O)Nc2cc(Cl)c(S(N)(=O)=O)cc2S(N)(=O)=O)c(C)c1 +O=C(CN1C(=O)C2(OCCCCO2)c2cc(Cl)ccc21)Nc1ccc(C(=O)NO)cc1 +C=C1ON=C2N1C(C)=CSC2(O)c1ccc(Br)cc1 +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncnc2ccc(C(=O)O)cc12 +CC#CCOc1ccc(S(=O)(=O)N2Cc3cc(N4CCOCC4)ccc3N(C(C)=O)CC2C(=O)NO)cc1 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+N=C(NCC(O)CO)c1c(O)nsc1Nc1ccc(Nc2ccc(Br)cc2)cc1 +CC(C)CC(NC(=O)c1cc(COc2ccccc2)ccc1CCC(=O)O)c1ccc(Cl)cc1 +CCNC(=N)c1ccc(C2=NOC(CC(=O)NCCC(=O)O)C2)cc1 +Nc1cnc(-c2ccc(C3CCC3)c(OCC(O)Cn3ccncc3=O)c2F)cn1 +CCOC(=O)c1ccc(NC2CCN(c3nnc(Cc4ccccc4)c4ccccc34)C2)nc1 +CCN(C(=O)c1cc(C)ccc1-n1nccn1)C(C)Cc1noc(-c2ccc(F)cn2)n1 +O=C(NCC=CCN1CCN(c2ccccc2OCCF)CC1)c1cc2cc(O)ccc2[nH]1 +O=C(Nc1ccc(C(=O)N2CCN(c3cccc(F)c3)CC2)cc1)N1Cc2ccccc2C1 +N=C(N)Nc1ccc(OC2CC(Oc3ccc(NC(=N)N)c4ccccc34)C(NC(=N)N)CC2NC(=N)N)cc1 +O=C1C(Br)=C(N2CC2)C(=O)C(Br)=C1N1CC1 +O=C(Nc1c(F)cccc1F)c1cccc(-c2nc3ccccn3c2-c2ccnc(Nc3ccc(CCN4CCOCC4)cc3)n2)c1 +Cc1ncnc(C)c1C(=O)NCCC(C)N1CCC(N2C(=O)N(C3CCCCC3)CC2c2ccc(Br)cc2)CC1 +Cc1cc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)cn2CC(CF)O3)no1 +O=S(=O)(c1cnc2ccccc2c1)N1CCC(CN2CCN(c3ccc(Cl)cc3)CC2)CC1 +NC(=O)c1nc(-c2ccncc2)sc1NC(=O)c1ccc(CN2CCOCC2)cc1 +Oc1cccc(-c2cc(-c3cccc(Cl)c3)nc3c2oc2ccccc23)c1 +COc1ccc(NCCNC(=O)C(Cc2ccc3ccccc3c2)NC(=O)c2cccc(C)c2)cc1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC4COC(c5ccccc5)OC4)c3)s2)nn1 +O=C(C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2)Nc1ccc(C(F)(F)F)nc1 +Nc1ncc(-c2ncccc2C(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)(COC(F)F)CC1 +COc1cccc2c1nc(N1CCNCC1)n2Cc1ccccc1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4C(C3)C4(Cl)Cl)n2)cc1OC(F)F +O=C(NN1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Br +c1ccc(CNc2ccc3[nH]nc(-c4nc5cc(N6CCC(N7CCCCC7)CC6)ccc5[nH]4)c3c2)cc1 +O=C(NC(Cc1ccccc1)C(=O)NNC(=O)c1ccccc1)OCc1ccccc1 +O=C(Nc1cc(-c2ccc3c(c2)OCO3)nc(-c2ccccc2)n1)C1CC1 +CC1CCC(Oc2cc(C(F)(F)F)nc3ccccc23)CN1C(=O)c1ccccc1-n1nccn1 +NC(=O)CC(NC(=O)CNC(=O)CNC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +COc1cc(N(O)O)ccc1S(=O)(=O)Nc1cnc2ccccc2c1 +O=S(=O)(c1ccc(F)cc1)N1CC2CC1CN2CCOc1ccccc1-c1ccccc1 +Cc1nc(C2CCCO2)c2c(N3CCc4cnn(C)c4C3)ncnn12 +Cc1cc(CN2CCCC2)ccc1C(=O)Cn1ccc(OCc2ccc(Cl)cn2)cc1=O +CN(CC=CC=Cc1ccc(-c2ccccc2)cc1)Cc1cccc2[nH]ccc12 +O=[N+]([O-])c1ccc(SC(=S)N2CCN(C(c3ccccc3)c3ccccc3)CC2)c([N+](=O)[O-])c1 +N#Cc1ccc(NC(=O)c2ccc3cccnc3c2O)cc1 +N#Cc1ccc2c(Cl)c(C(=O)Nc3ccccc3)sc2c1 +CCCn1ccc(-c2cc(-c3ncc(C)cn3)n3cc(NC(=O)NCC)nc3c2)cc1=O +CSc1nn2c(=O)cc(N3CCOCC3)nc2n1Cc1cccc(C(F)(F)F)c1C +CCCCC12CCC(=O)C(C(=O)OC)=C1c1ccc3[nH]ncc3c1C2 +Nc1nc(OCCc2c[nH]c3cc(Cl)ccc23)nc2c1ncn2C1OC(CO)C(O)C1O +CN(C)C1CCN(C(=O)c2cccc(Nc3nc4nc5c(cnn35)CCCCC(=O)Nc3cccc(c3)N4)c2)C1 +OC1(c2ccc(Cl)cc2)CCN(CCCC(c2ccccc2)c2ccccc2)CC1 +COc1ccc(OC)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2cccnc2)c1 +O=C(Nc1cc2ccc(-c3cnccc3C(F)(F)F)cc2cn1)C1CC1 +Cc1ccc(-c2cncc(C(CC(=O)O)NC(=O)C3CCCN(C(=O)CCC4CCNCC4)C3)c2)cc1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)C1)c1ccc(-c2cccs2)cc1 +Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCC(C)C)CC(=O)N2 +O=S(=O)(c1ccc2ccccc2c1)c1n[nH]c2ccc(NC3CCNCC3)cc12 +CCc1nc2ccccc2n1-c1nc(N2CCOCC2)c2nc(CN3CC(C4CCOCC4)C3)n(C)c2n1 +Cc1ccc2c(c1)N(C)C(=CC=Cc1oc3ccccc3[n+]1C)O2 +CC(C)COc1cn(-c2ccc(C(=O)O)cc2)cc1C#N +O=C(C1CCCN1S(=O)(=O)c1ccc2ccccc2c1)N1CCN(c2ccnc3cc(Cl)ccc23)CC1 +COc1ccc(CNC2COC(C(c3ccccc3)c3ccccc3)CC2O)c(F)c1 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+Cc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)NC4CCN(C5CC5)CC4)cc3Cl)nc1-2 +CC(C)Oc1cc(C2(Cc3cccc(OC(F)(F)F)c3)CN(CC(O)C(F)(F)F)c3ccccc32)ccn1 +C=CCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c2cc(-c3ccco3)ccc21 +O=Cc1ccn(-c2cc3c(cc2C(F)(F)F)nc(O)c2nc(C(=O)O)nn23)c1 +O=C(c1ccccc1N1Cn2c(ccc2-c2ccccc2)C1=O)N1CCCCC1 +CC(C)N1CCc2nc(C#Cc3ccccc3)ccc2C1=O +COc1ccc2c(c1)C1(CCN(C)CCO)CCCCC1C=C2 +CNC(C)C(=O)NC(C(=O)NC1CCCN(CCc2c[nH]c3ccccc23)C1)C(C)(C)C +CN(CCOc1cc(Cl)ccc1Cl)CCN1C(=O)CC2(CCCC2)CC1=O +CCc1ccc(-c2nc(C)oc2-c2ccc(S(C)(=O)=O)cc2)s1 +CC(=O)c1cccc(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)c1 +C=CCC(C(=O)NO)N(Cc1cccnc1)S(=O)(=O)c1ccc(OC)cc1 +COc1cccc2c(=O)[nH]c(-c3ccc(C)cc3)nc12 +Cc1nc(NC(C)c2ccnc(Cl)c2)cc(-c2ccc3ncsc3c2)n1 +O=C(Cc1ccccc1O)NCCCNCCCCCCCCNCCCNC(=O)Cc1ccccc1O +CNC(=O)Cc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +c1ccc(C(c2ccccc2)N2CCN(c3ncnc4c3cnn4-c3ccccc3)CC2)cc1 +CC(C)N1CCC(Oc2ccc(C(=O)NC3CCN(C4CCC4)C3)c(F)c2)CC1 +O=C(O)c1ccc(CCCN2C(C=CC(O)Cc3cccc(OC(F)(F)F)c3)CCS2(=O)=O)s1 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+O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1cc(Cl)cn12 +CCOC1CCC(N2CC(NC(=O)CNc3n[nH]c4ccc(C(F)(F)F)cc34)C2)CC1 +O=C1COc2ccc(OCC3CCCN(CCOc4cccc5ncccc45)C3)cc2N1 +CCCNC(=O)Oc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +CN(CCO)Cc1ccn2c(-c3ccnc(N)n3)c(-c3ccc(F)cc3)nc2c1 +O=C1CCCN1c1ccc(S(=O)(=O)NNc2ccc(Br)cc2)cc1 +Cn1cc(NC(=O)c2ccc3nc4n(c3c2)CCCNC4=O)cn1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(F)cn3)c2)c2cnccc21 +CC(C)(CC(O)(Cc1cc2cc(N3CCOCC3)ncc2[nH]1)C(F)(F)F)c1ccccc1S(N)(=O)=O +Cc1nc(N2CCC(O)C2)ccc1-c1cc(C(F)(F)F)cc2[nH]ncc12 +COc1ccc(C(=Cc2cc(OC)c(OC)c(OC)c2)C(N)=O)cc1N +O=[N+]([O-])c1ccc(Cc2ccc3ccccc3c2O)cc1 +COc1cc(C(=O)N2CCC2c2nc(-c3cccc(F)c3OC)no2)c(-n2nccn2)cc1C +Cn1cc(-c2ccc(Cn3cc(C(=O)NC4CCOCC4(C)O)c4ncccc43)c(F)c2)cn1 +CC1CCC2C(C)C(OCc3ccc(C(=O)O)cc3)(C(F)(F)F)OC3OC4(C)CCC1C32OO4 +Cc1cc(C)[n+](CC(=O)Nc2nccc(Nc3ccc(S(N)(=O)=O)cc3)n2)c(C)c1 +CCn1ncc2c1CN(c1ncnn3c(C)nc(C4CCOC4)c13)CC2 +c1ccc2c(c1)c1cc[n+]2Cc2ccc(cc2)C[n+]2ccc(c3ccccc32)NCc2ccc(cc2)CN1 +CN(C)c1ccc(C(=O)C=Cc2ccc(I)cc2)cc1 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+O=[N+]([O-])c1ccc(NCCNc2ncc(-n3cnnn3)c(-c3ccc(Cl)cc3Cl)n2)nc1 +COC(c1ccc(Cl)cc1)(c1ccc2c(c1)c(-c1ccccc1C(F)(F)F)cc(=O)n2C)c1cncn1C +CC12CCCC(C=CC(=O)NS(=O)(=O)c3ccc(F)cc3)=C1N(Cc1ccc(Cl)cc1Cl)C(=O)C2 +CCCCCCCCC=CCCCCCCC(=O)c1ncc(-c2ccccn2)o1 +O=C(c1cc(Cc2c[nH]c(=O)c3cc(Cl)c(Cl)n23)ccc1F)N1CCC(N2CCC2)CC1 +O=C(Cc1ccccc1)Nc1nc(-c2cccs2)nc2cn(-c3ccccc3)nc12 +COc1cccc(-c2ccc(N3CC4CN(C)CC4C3)cn2)c1 +C=CCNc1nc(N2CCC(NCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)nc2c1ncn2CC=C +Cc1ccccc1-c1ccc2nc(N)c(CCC(=O)NCC3CCCCC3)cc2c1 +CC#CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CCCCC1CCN(C(=O)OC(C)C)CC1)c(=O)n2C +COc1cccc(-c2csc(C3(CNC(=O)c4ccc(Cn5nc(C)cc5C)cc4)CCOCC3)n2)c1 +CC(C)(C)COc1ccc(-c2cc(O)nc(N)n2)cc1C#N +O=C1NC(c2cncc(C#CC3CC(F)(F)C3)c2)C(c2ccc(F)cc2F)O1 +Cc1cc(C)cc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Cl)cc2)c1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3cc(Cl)ccc3[nH]2)n1 +Cc1nc(Nc2c(Cl)cc(C(F)(F)F)cc2Cl)c(=O)n(C(C)C2CC2)n1 +CC(C)(C)N(CCC(N)=O)C(=O)c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1 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+O=[N+]([O-])OCCCN1CCN(Cc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2O)CC1 +O=C(NCc1cccc2ccccc12)c1cc(-c2ccncc2)nc2ccccc12 +CNC(=O)CC1OC(n2cnc3c(NCc4ccccc4)ncnc32)C(O)C1O +CC(C)(C)C1NC(=O)C(CN(O)C=O)CCCCCCCCCCNC1=O +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCCN3C)cc12 +COC(=O)C1CC(OC(=O)CSC#N)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +CCC(CO)Nc1nc(NCc2ccccc2)c2ncc(C(C)C)n2n1 +Cc1cnc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cn1 +CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1Br +COc1ccc(CN2CCC(CCCC(=O)c3ncco3)CC2)cc1 +CCCCn1c(=O)n(CC(=O)NC(C)(C)C)c(=O)c2c(C)cccc21 +CC(=O)Nc1nc(CCc2ccc(-c3c[nH]c(N)n3)cc2)cs1 +CCOC(COC1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1)c1ccccc1 +CC(C)COc1cccc(O)c1-c1cc(C2CCNCC2)c(C#N)c(N)n1 +O=c1[nH]c(C2CCN(C3CCOC3)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +CC(O)CN1c2cccc(-c3cccc(OC(F)(F)F)c3)c2CCC1c1cccc(OC(F)(F)F)c1 +COc1ccc(Cc2cc(C3CCN(C(=O)c4ccc5c(c4)OCO5)CC3)nc(Cl)n2)cc1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2nc(-c3ccccc3)c(Oc3ccccc3OC)s2)cc1 +CC(Nc1cccc(F)c1C#N)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +CCCC1CN(Cc2cc(Cl)ccc2OCC(=O)O)CCN1S(=O)(=O)c1ccccc1 +O=C1c2cccc3cc(O)cc(c23)C(=O)N1CC1CCN(CC(O)COc2cccc3[nH]c4ccccc4c23)CC1 +Cc1cc(Cl)cc(Cl)c1CNC(=O)C1CCCCc2ncsc21 +COc1cc(-c2c(C(C)C)cccc2C(C)C)ccc1C(C)C#Cc1c(C)nc(N)nc1N +N#CC(Cc1ccc(-c2cccc(C(N)=O)c2)cc1F)NC(=O)C12CCC(CC1)CN2 +On1cc(C2CCNCC2)c(-c2cn(Cc3ccccc3)c(Cl)n2)n1 +CCC(c1ccc(-c2ccc(=O)n(C)c2)cc1)N1CCC(CC)(c2ccccc2)OC1=O +Cc1nnc(C(N)CCC(=O)Nc2cc(Cl)cc(S(=O)(=O)O)c2O)o1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CCC(n4cn[nH]c4=O)CC3)cc2F)cn1 +COc1ccc(-n2nnnc2C(F)(F)F)cc1CNC1CCN(C(=O)C2CN(C(C)=O)C2)CC1c1ccccc1 +CN1CC2CN(Cc3c2c2ccccc2n3Cc2ccc(C(=O)NO)cc2)C1=O +COc1ccccc1N1CCCN(CCCCNC(=O)c2ccc(CCF)cc2)CC1 +CNCC(NC(=O)c1ccc(-c2nc(C3CCC(O)CC3)cnc2N)cc1F)c1cc(F)cc(Br)c1 +Cc1cnc(-c2cccc(Cl)c2)nc1N(C)CCCOc1ccc2c(c1)CCC2CC(=O)O +CCC(c1nc2snc(C)c2c(=O)n1Cc1ccccc1)N(CCCN)C(=O)c1ccc(C)cc1 +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1N1CCC(O)CC1 +Cc1ccc(-c2cc(Cl)ccc2OCC2CCCC2)n1-c1cccc(C(=O)O)c1 +CC(CCCn1cnnn1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +O=C(Nc1nnc(SCc2ccc(F)cc2)s1)c1ccc(Cl)cc1 +CCc1n[nH]c(CC)c1Oc1cc(C#N)cc(C#N)c1 +COc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3ccc(OCCN4CCCCC4)cc3)CC2)cc1 +O=C(Nc1ccc(F)cc1)NC1C2CCN(CC2)C1Cc1cccnc1 +COc1c(Nc2ncc3c(n2)N(C2CCCC2)CC(F)(F)C(=O)N3C)ccc(C(=O)NC2CCN(C)CC2)c1F +CC(=O)NC1CC(COC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)NC1=O +O=S(=O)(c1ccccc1)c1cc(Nc2cc(-c3ccc(F)cc3)[nH]n2)nc(NC2CCC(O)CC2)c1 +COc1cc(-c2cnc[nH]2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc12 +O=c1c2cn[nH]c2c2ccc(-c3ccncc3NS(=O)(=O)c3cccc(Cl)c3)cc2n1CC(F)(F)F +COc1cccc(C(=O)NCCN2CCN(c3ccccc3Cl)CC2)c1 +CCC1(O)Cc2cc3n(c(=O)c2COC1=O)CC1=C(CN2CCC(C)CC2)C2C=C(C)C(Cl)=CC2N=C13 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2CN1CCN(S(=O)(=O)c2ccccc2)CC1 +CCCN1CCC(N(C)CCc2ccc(OC)c(OC)c2)CC1 +CNc1ncnc(-c2cc(C)cnc2Oc2cc(C(=O)Nc3cc(C(F)(F)F)ccc3N3CCCCC3)ccc2C)n1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc(-c2ncccc2C(F)(F)F)cc1F +N#CC1CC(F)CN1C(=O)C(N)Cc1ccccc1C(F)(F)F +c1cc(N2CCC(N3CCCC3)CC2)ccc1CCN1CCC1 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+O=C(CC1CCCCN1c1cc(-n2ccnc2)nc(-n2ccnc2)n1)NCc1ccc2c(c1)OCO2 +C#CCNC(=O)c1ccc(OC2CCN(CC(c3ccccc3)c3ccccc3)CC2)c(OC)c1 +Oc1ccc(C2=c3ccc4n3C3C(=CC=4)CCCCC23)cc1 +CCN1C(=O)C(C)(C)C(=O)N(C)c2cc(OCCCN(CCc3cccnc3)S(=O)(=O)c3ccccc3)ccc21 +C=COC(=O)N(C)N=Nc1ccc2ncnc(Nc3cccc(Cl)c3)c2c1 +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)c1ccccc1-c1ccccc1 +Cc1nc(-c2ccc3c(c2)c(C#N)cn3CCNS(C)(=O)=O)sc1C(=O)O +COC1CC(CF)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +CNCCOc1ccc(C(=C(CCCO)c2ccccc2)c2ccc(O)cc2)cc1 +N#CC1CSCN1C(=O)CN(N)C1CCN(CC(=O)Nc2ccc(Cl)cc2)CC1 +COc1ccccc1-c1cc(-c2ccccc2C#N)c(=O)n(-c2ccccc2)c1 +COc1ccc(Cl)cc1CC1CNC(=NOc2ccccn2)CN(C(=O)NC(C)c2ccc(C(=O)O)c(N)c2)C1=O +COc1cc(OCCCN(C)Cc2ccc(OC)c(OC)c2)ccc1NC(=O)c1cccc2c(O)c3cccc(F)c3nc12 +CCC1CN2CCc3cc(OC)c(OC)cc3C2CC1CC1NCCc2c1cc(OC)c(OC)c2Br +Cc1nc2cccc(-c3cc4c([nH]3)C(C)NC4=O)c2nc1NC(C)C +Cc1cc(C(=O)N2CC(C)NC(C)C2)[nH]c1C=C1C(=O)Nc2ncnc(Nc3ccc(F)c(Cl)c3)c21 +COCc1nc(NC(=O)NC(c2ccccc2)C2CCCO2)cc2[nH]nc(OC)c12 +CC(C)Oc1cccnc1N(C)C1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +Cn1ncc(NC(=O)c2nc(-c3ccccc3F)ccc2N)c1N1CCC(N)CC(F)(F)C1 +c1cnc(Oc2ccc(Nc3nc4ccccc4[nH]3)cc2)c(C2CCOCC2)c1 +COc1ccc(OC)c(N(C(=O)Oc2c(C)cccc2C)c2ccnc(Nc3ccc(N4CCN(C)CC4)cc3)n2)c1 +CCCCCCCCCC(=O)Nc1ccc(CP(=O)(O)O)cc1 +CCc1cc(=NCCC2CCN(Cc3ccccc3)CC2)[nH]nc1-c1ccccc1 +CCCCc1nnc(SCC(=O)c2ccccc2)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +CCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C +CCc1nn2c(C)cc(C)nc2c1Cc1ccc(OCC2CCNCC2)cc1 +O=C(c1ccc(-c2ccccc2)s1)c1c(F)ccc(O)c1F +Cc1ccc(CN2CCN(Cc3cccc4c3OCO4)CC2CCO)cc1 +CC1CCC(Cn2c(N3CCOCC3c3ccccc3)nc3cc(-c4n[nH]c(=O)o4)nc(-c4cncc(Cl)c4)c32)CC1 +O=C(C=Cc1cccc([N+](=O)[O-])c1)NCCCCNc1c2ccccc2nc2ccccc12 +O=C1CSCN1CCCCN1CCN(c2ccc3ccccc3n2)CC1 +COC(=O)C(C)(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)C(=O)OC +Cc1cccc(CC(O)C=CC2CCC(=O)N2CCSc2ccc(C(=O)O)s2)c1 +C[Si](C)(C=CCN1CC(O)C(O)C(O)C1CO)c1ccccc1 +CC(NC(=O)C=Cc1ccccc1F)c1ccc2c(c1)N(C)CCO2 +CCCCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(c1ccccc1Oc1ccccc1)N(C1CCC1)C1CCNC1 +Nc1cc(C2CCCNC2)nc2c(-c3cncnc3)cnn12 +COc1ccccc1C1c2c(n[nH]c2C(C)(C)C)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 +COc1cccc(CNC(=O)C2(Cc3ccccc3)OC(=O)N(C(C)c3ccccc3)C2=O)c1 +O=C1COCC2=C1C(c1ccc(F)c(Br)c1)C1=C(COC1=O)N2 +CN(C)Cc1ccc(NC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)cc1 +CCCCCCN1CCN(c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)C1=O +Cc1cc(NC(=O)C2C(C)(C)C2(C)C)ccc1N1CCC(N2CCCC2C)C1 +O=C(O)C(O)=Cc1cc(OCc2ccc(F)cc2)ccn1 +[H]C([H])(CCCC)C([H])([H])C(C)(O)C1CCC2C3CC(O)C4CC(O)CCC4(C)C3CCC21C +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5ccccc5)co4)cc3)cc2)C(=O)NC(=O)NC1=O +CN1CCC=C(c2nsnc2OCCCCNCCCCCCCCNc2c3c(nc4ccccc24)CCCC3)C1 +CC(C)C12OC1C1OC13C1(C)CCC4=C(COC4=O)C1CC1OC13C2(O)CNc1ccc2c(c1)CC(=O)O2 +CN(CCCNC(=O)c1cccc2nc3cccc(Cl)c3nc12)CCCNC(=O)c1cccc2nc3cccc(Cl)c3nc12 +N#Cc1ccc2c(c1)C1CN(CCCCNC(=O)c3ccc(-c4ccccc4)cc3)CC1CO2 +CCCC(=O)Nc1nc(-c2ccccc2)cc(-c2ccc3c(c2)OCO3)n1 +Cc1cc(S(=O)(=O)NCc2ccncc2)cnc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +Cc1ccc(OCC(=O)Nc2cccc(CCc3n[nH]c(=O)c4c3CCCC4)c2)cc1 +O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1ccc(F)c(F)c1 +CN(C(=O)C1(c2ccccc2)CCCC1)c1ccccc1Cl +CN(C)CCOc1ccc(-c2nc(-c3ccncc3)c(-c3ccc4c(c3)CCC4=NO)[nH]2)cc1 +COc1cc(C2=NCCN2)ccc1-c1cn(-c2ccc(C3=NCCN3)cc2)nn1 +O=C(O)c1ccc(CCC2C(=O)CCC2C=CC(O)Cc2cccc(Br)c2)cc1 +CCOc1cccc(-c2ccc(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)c(OC)c2)c1 +O=C(O)c1cccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)c1 +CCc1cc(C(SCC(N)C(=O)O)(c2ccccc2)c2ccccc2)ccc1C +O=C(N1CCc2ncc(C(F)(F)F)cc2C1)C12CCOC1CC(N1CCC(c3ccccc3)CC1)C2 +O=C(NN=Cc1ccc(O)cc1)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC1CCOC1 +O=c1[nH]nc(CN2CCN(c3nc4cc(F)ccc4n4cccc34)CC2)o1 +CC(C)c1onc(COc2c(Cl)cc(F)cc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +CCc1nc(Oc2cc(C)ccn2)c(CC)nc1NC1c2ccccc2CC1OC1CC1 +Cc1cnc2c(C(F)(F)F)cccc2c1-c1cccc(CNc2cccc3c(CC(=O)O)cccc23)c1 +Cc1c(Cc2ccccc2)nnc(N2CCN(c3cnc(C(=O)N4CCOCC4)cn3)C(C)C2)c1C +CCCCc1nc(Cl)c(CO)n1Cc1ccc(C(=O)c2ccccc2C(=O)O)cc1 +O=C(O)C(CCC(=O)N1CCC(CCCC2CCNCC2)CC1)NS(=O)(=O)c1ccccc1 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+COc1cc(Sc2c(-c3ccccc3)[nH]c3cccc(Cl)c23)cc(OC)c1OC +Cc1cc(C)cc(S(=O)(=O)c2c(C(N)=O)[nH]c3ccc(Br)cc23)c1 +CC1CCCCN1CCCNc1ncc2cc(-c3c(Cl)cccc3Cl)c(NC(=O)NC(C)(C)C)nc2n1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCN(C(=O)NC#N)CC3)cc12 +CC(C)Nc1nc(-c2ccc(C(C)O)cc2)cc2ncn(C)c(=O)c12 +O=C(O)CNC(=O)C1=C(O)CCN(Cc2ccc(Oc3ccc(C(F)(F)F)cn3)cc2)C1=O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(CN5CCCC5)s4)nc23)N1 +FC(F)(F)c1ccc(Nc2nnc(-c3ccncc3CCc3ccncc3)o2)cc1 +CCc1c(Sc2ccccc2)n(OCCC2CCCCC2)c(=O)[nH]c1=O +COc1cc(C)c(CC(N)C(=O)NC(C)C(=O)NCCCc2ccccc2)c(C)c1 +COc1cccc(-n2nc(C)c3c(O)c4ccccc4nc32)c1 +CC(C)CC(N)P(=O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)O +Fc1ccc(F)c(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)c1 +O=S(=O)(Nc1ccc2nccc(N3CCNCC3)c2c1)c1cc(Cl)cc(Cl)c1 +Cc1ccc(C(=O)N2C3CCC2C(Nc2cnc(C(F)(F)F)cn2)C3)c(-n2ccnn2)n1 +CCC(CO)Nc1cc(-c2[nH]c(SC)nc2-c2ccc(F)cc2)ccn1 +O=C(Nc1cc(Cl)ccc1N1CCC(CO)CC1)c1cnn2cc(O)cnc12 +Cc1nn(-c2ncnc3nc[nH]c23)c2c1C(OCC(=O)c1ccc(F)cc1)CC(=O)N2 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+COc1ccccc1N1CCN(CCn2c(=O)[nH]c3scc(-c4cccc(C)c4)c3c2=O)CC1 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC(CO)CO +CNC(=O)c1nn(C)cc1NC(=O)c1nc(CC(C)C)ncc1Nc1cncnc1 +COc1ccc(C(=O)N2CCN(c3cc4c(cc3F)c(=O)c(C(=O)O)cn4C3CC3)CC2)c(O)c1 +O=C(c1ccc(O)cc1)N1CCCC2c3ccccc3CC21 +CCC(NC(=O)c1ccc2c(ccn2Cc2ccc(Cl)nc2)c1)c1ccccc1 +COC(=O)C=CC=CC(=O)N1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 +O=C1NCCc2ccc3c(c21)CC(N(CCCc1c[nH]c2ccc(F)cc12)C(=O)c1ccccc1)CO3 +Nc1cnc(-c2ccc3c(c2)CN2CCC3(c3ccc(Cl)c(Cl)c3)CC2)cn1 +CCN(c1c(C)nn(C)c1C)S(=O)(=O)c1c(Cl)cc(CCCC2CCNCC2)cc1Cl +CSc1cncc(N2C(=O)CN(c3cccc(C(F)(F)F)c3)CC2C(=O)NC2CCCC2)c1 +CC1CN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CC4CC3CO4)n2)CC1F +COc1ccc(C2=C(c3cccs3)C(=Cc3ccc(C=CC(=O)O)o3)NC2=O)cc1OC +CN1C(=O)c2c(Cc3ccccc3)nn(C)c2N2C1=NC1CCCC12 +Cc1[nH]c(C(=O)NC2CCN(c3ncc(C(=O)O)s3)CC23OCCCO3)c(Cl)c1Cl +OCC1CCCN1CCOc1ccc(C2Oc3ccc(O)cc3SC2c2ccc(O)cc2)cc1 +Cc1nnc(-c2ccc(-c3ccccc3)cc2)n1-c1cccc(OCCCCCCN2CCN(C)CC2)c1 +c1ccc(Cn2nnnc2C(c2ccc(Oc3ncccn3)cc2)N2CCCN(C3CCC3)CC2)cc1 +CC(Nc1c(-c2c(F)cc(NCCCN(C)C)cc2F)c(Cl)nc2ncnn12)C(F)(F)F +CCC(CC)Oc1ccc2n(n1)c(N)n[n+]2CC(=O)c1cc(Cl)cc(OC)c1 +Cc1ncc([N+](=O)[O-])n1CCNS(=O)(=O)ON +Cc1ncc(F)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COc1ccc(C)cc1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 +CCCN1CCC=C(c2ccc(Nc3nc(Nc4cc(F)ccc4C(N)=O)c4cc[nH]c4n3)c(OC)c2)C1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN2CC(C)(c3ccccc3)CC2C1 +CCc1nc2c(C)cc(C)nc2n1Cc1cc(Cl)c(OC(C(=O)O)c2ccccc2)c(Cl)c1 +CCC1C(C)C(Nc2ccccc2)c2ccccc2N1C(=O)Nc1ccccc1 +COc1cccc(CC2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)c1 +COc1ccc(CN2CCN(CCCCCCCCN3C(=O)c4ccccc4C3=O)CC2)cc1 +CN(C)c1ccc(C=Cc2cc(-c3ccccc3)o[n+]2C)cc1 +O=S(=O)(Cc1ccccc1)N1CCC(NC(c2cnccn2)c2ccc(F)cc2F)CC1 +CCOP(=O)(O)CCCCn1c(-c2cccnc2)c(C)c2ccccc21 +COc1ccc(CNC(=O)c2ccc(CC(NC(=O)C3CCC(=O)N3Cc3ccccc3)C(=O)O)cc2)cc1 +CN(CCCc1ccccc1)C(=O)c1cc2ccccc2[nH]1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3cccc(F)c3)o2)C(C)O)c(C)c1Cl +CC(C)(C)c1ccc(-n2nnnc2SCC(=O)Nc2ccc(S(C)(=O)=O)cc2Cl)c(Cl)c1 +CCCn1c(=O)c2nc(C3CCC(C(=O)N(C)CCN(C)C)CC3)[nH]c2n(CCC)c1=O +O=C(O)c1cnc(NC2CC2)n2nc(-c3ccco3)nc12 +CCOC(=O)c1cccc(NC(=O)Nc2ccc(-c3c(C)sc4ncnc(N)c34)cc2)c1 +COc1cccc(C(=O)Nc2cc(-c3ccccc3)nn2-c2ccccc2)c1 +O=C(N1CCC(c2c[nH]c3ncccc23)C1)C1(c2ccc(Cl)cc2)CC1 +CNCc1ccccc1-c1ccc(N2CCc3c(C(N)=O)nn(-c4ccc(OC)cc4)c3C2=O)cc1 +Cc1nc(C)c(CNc2cc(C(=O)NCCc3ccccn3)nc3ccnn23)s1 +CC(O)CNC(=O)N1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1 +COc1ccccc1Cc1c(C(=O)c2ccc(C)cc2C)oc2cc(O)ccc12 +C=CC(=O)Nc1cccc(CNc2nc(Nc3ccc(N4CCNCC4)cc3OC)ncc2C2CC2)c1 +CCC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)nc2c1Nc1ccc(N2CCCC(N)C2)nc1 +c1cc2ccc(-c3nc(N4CCOCC4)c4nc[nH]c4n3)cc2[nH]1 +OCC1CCN(CC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)C1 +COc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)ccc1-c1cccnc1Cl +CN(C)C(=O)Oc1ccc(-c2cn3c(NC(=O)c4ccccc4)cccc3[n+]2C)cc1 +CC(C)n1nc(-c2ccc3c(ccn3C)c2)c2c(N)ncnc21 +CC(C)c1nn(-c2ccc(C(N)=O)c(NCC(F)(F)F)c2)c2nccc(-n3cnc(-c4cnn(C)c4)c3)c12 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(CNCCC(=O)O)cc2C)ncn1 +N#Cc1cc2c(Oc3ccc(F)cc3OCCn3ccc(=O)[nH]c3=O)cccn2c1 +CCCS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1 +c1ccc(C(CCc2nc(CCNCCc3ccccn3)c[nH]2)c2ccccc2)cc1 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3cc(Cl)ccc23)C1(C)C +N=C(N)c1cccc(CN2CCC(NS(=O)(=O)c3ccc4cccnc4c3)C2=O)c1 +O=[N+]([O-])C=C(NCCCn1ccnc1)Nc1ccc2c(c1)OCCO2 +Nc1cc(-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3cccnn3)cc2Cl)ccn1 +Cc1c(C(=O)CSc2ccc(C(=O)Nc3ccc(F)cc3)cn2)sc2ccc(Cl)cc12 +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(C(F)(F)F)c(Nc2ccc(N3CCN(C)CC3)cc2OC)n1 +C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1ccc(C(C)C)cc1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccnc(C#N)c1 +Cc1cc(-c2ccccc2)cc(C)[n+]1CC(=O)Nc1ccc2nc(S(N)(=O)=O)sc2c1 +O=C1CN(Cc2cncn2Cc2ccc(-c3cc(Cl)cc(Cl)c3)cc2)CCN1c1cccc(Cl)c1 +CCCN(c1ccccc1Br)S(=O)(=O)c1ccc(O)c(C(F)(F)F)c1 +N=C(N)c1cccc(C2=NOC(Cn3cnnn3)(C(=O)Nc3ccc(-c4ccccc4S(N)(=O)=O)cc3Cl)C2)c1 +CC(C)n1nc(-c2cc3cc(C=O)ccc3s2)c2c(N)ncnc21 +FC(c1ccc(Cl)cc1)(c1cccnc1)c1ccccc1Cl +CN1CCC(NC(=O)c2cnc(NCc3cc(Cl)ccc3Cl)nc2NC2CCCC2)CC1 +O=C1COc2c(cccc2C(O)CNCCN(C(=O)CCNCCc2ccc(Cl)c(Cl)c2)C2CCCCC2)N1 +COC(=O)C(Cc1cccc(C(=N)N)c1)C(C=Cc1ccccc1)NC(=O)c1ccccc1 +Cc1[nH]c(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)NC2CCC(C)CC2)nc1C(=O)O +NS(=O)(=O)c1cc(C(=O)c2ccc(CNCc3ccccc3)cc2)cs1 +Nc1ncnc2c1sc1cc(-c3ccc(CO)cc3)ccc12 +CCC(C)(Cc1ccc(OCCCOc2ccc(C(F)(F)F)cc2Cl)cc1)C(=O)O +OC(CN1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccc(Br)cc1 +CC(C)S(=O)(=O)NCC1CCC(NC(=O)Cn2ccc3ccccc32)CC1 +CN1C(=N)NC(C)(c2sc(-c3cncc(-c4cnco4)c3)cc2F)CS1(=O)=O +COC(=N)NS(=O)(=O)c1ccc(NC(=O)C(Cc2ccccc2)NC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 +CC1(CNCC2CCN(c3ncccn3)CC2)COc2ccccc2O1 +CC#CCC(C)C(O)C=CC1C(O)CC(F)C1CC(=O)CCCCC(=O)O +Cc1cccc(N2Cc3cccc(C(N)=O)c3C2=O)c1 +COc1cc(C=NNC(=O)CC2(C)OCCCO2)ccc1OCc1ccccc1 +COCCNCCc1ccc(-c2cc3ncn(C)c(=O)c3c(NC(C)C)n2)cc1 +O=C(C=CC(=O)NCCCN1CCOCC1)Cc1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +O=C(NCCc1cccs1)NCc1cccc(-c2cccc(-c3cc4c[nH]ccc-4n3)c2O)c1 +CC(C)Cc1ccc2c(NCCCNCc3ccco3)ccnc2c1 +CS(=O)(=O)c1cccc(-c2ccc3ncc(-c4cncc(S(C)(=O)=O)c4)n3n2)c1 +Cc1ccccc1NC1=CC(=NS(=O)(=O)c2cccs2)c2ccccc2C1=O +Cc1c(Cl)cccc1CCCCOc1ccc(C#Cc2cccc3c(CCC(=O)O)c(C)n(CCC(=O)O)c23)cc1 +Cc1cc(CN2CCC(O)CC2)ccc1C(=O)Cn1ccc(OCc2ccccc2)cc1=O +COC(=O)c1c(Cc2ccc(C(=O)NC3C4CC5CC3CC(N)(C5)C4)cc2)c(=O)c2cccnc2n1-c1ccccc1 +Cc1cc(Nc2nc(NCc3cc(-c4ccccc4)no3)ncc2Br)[nH]n1 +CN(C)CCNc1n[n+]([O-])c2ccccc2[n+]1[O-] +CC(C)CC(CP(=O)(O)C(N)CC(C)C)C(=O)O +Cn1nc(NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)cc1-c1ccccn1 +N#Cc1cc(-c2nc(N)[nH]c(=O)c2Cl)ccc1OCCCCO +OC1C[N+]2(Cc3ccc(CCc4ccc(C[N+]56CCC(CC5)C(O)C6)cc4)cc3)CCC1CC2 +Cc1cnc(C(CO)Cc2cccc3ccccc23)cc1OC1CCCCC1 +Fc1ccc(Cn2c(NC3CCNCC3)nc3ccccc32)cc1 +OC1(c2ccc3ccccc3c2)c2ccc3ccccc3c2C2=NCCN21 +Cc1c[n+]([O-])cc(C)c1C(=O)N1CCC(C)(N2CCN(C(C)c3ccc(C(F)(F)F)cc3)C(C)C2)CC1 +CCOc1ccc(S(=O)(=O)N2CCC(n3cc(C)c4cc(Cl)ccc43)CC2)cc1 +Cc1c(C(=O)Nc2ccc(Oc3ccnc4[nH]ccc34)cc2)nnn1-c1ccccc1F +NS(=O)(=O)c1ccc(-n2nc(-c3ccc(C4CCCCC4)cc3)ccc2=O)cc1 +CN1CCCC1CCN1CCCc2cc(NC(=N)c3cccs3)ccc21 +COC12CCC3(CC1CNC(=O)CCc1nnn[nH]1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +OCC1OC(Oc2ccc(-c3ccc(C(F)(F)F)cc3)cc2Cl)C(O)C(O)C1O +O=C(Nc1cccnc1)N1CCC2(CCCN2Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +Nc1nc(N)c2c(-c3ccc(F)cc3)c(-c3ccc(F)cc3)[nH]c2n1 +Cc1cccc(NC(=O)NC2N=C(c3ccccc3)c3ccccc3N(CC(=O)C(C)C)C2=O)c1 +Cc1c[n+](Cc2ccccc2)ccc1C=Cc1ccccc1 +CN(C)Cc1ncccc1-c1ccc(-c2ccc3c(C(N)=O)nn(-c4ccc5onc(N)c5c4)c3c2F)c(F)c1 +Cc1nc(N)nc(-n2c(Nc3ccc4cc[nH]c4c3)nc3ccccc32)n1 +COc1ccc(C(=O)c2cccc(C=c3[nH]c(=O)c(=Cc4nc[nH]c4C(C)(C)C)[nH]c3=O)c2)cc1 +CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(-c2ccc(OCc3ccc(Cl)cc3)cc2)cc1 +COc1ccc(S(=O)(=O)N2CCN(C(=O)NCc3ccccc3)CC2C(=O)NO)cc1 +COc1ccc(N2CC(CN3CCC(O)(c4ccc(Cl)cc4)CC3)OC2=O)cc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCCCCC1=O +CC1C(c2ccccc2)CC(NC(=O)c2cnc3c(c2)CC2(C3)C(=O)Nc3ncncc32)C(=O)N1CC(F)(F)F +CCCNc1ncc(-c2cc(-c3ccc(F)cc3)nc(-c3ccccn3)n2)s1 +CC(Nc1cncc(Cl)n1)c1cccc(NC(=O)c2cncc(Br)c2)c1 +COc1ccc(-c2c(COC(C)=O)c(COC(C)=O)cc3ccc4c(c23)OCO4)cc1OC(C)=O +CC1OC(n2cc(-c3ccccc3)c3c(NCC(=O)NC4CCC4)ncnc32)C(O)C1O +CC1CCC(Oc2nccc3ccccc23)CN1C(=O)c1ccccc1-n1nccn1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=NCCN(C)C +Cn1c(-c2ccccc2)c(C2CCCCC2)c2ccc(C(=O)O)nc21 +CCCCCCN1C(=O)N(CCCC)C(=O)C1=Cc1cnc(CCCC)n1Cc1ccc(C(=O)OC)cc1 +Nc1nc(O)c2ncn(Cc3ccccc3CCP(=O)(O)O)c2n1 +O=C(c1ccc(F)cc1-n1nccn1)N1CCC2CN(c3nc4cc(Cl)ccc4o3)C2C1 +Cc1cc(S(=O)(=O)NCc2cccnc2)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)Nc1ccccc1 +CC1=C2CCc3cc(C(=O)Oc4ccccc4C(F)(F)F)ccc3N2CCC1=O +COC(=O)c1ccc(-c2c(C)[nH]c3cc(OC)c(Cl)cc3c2=O)cc1 +O=P(O)(O)C(CCCc1cccc(Oc2ccc(Cl)cc2)c1)S(=O)(=O)O +O=C(NCCCCN1CCN(c2ccccc2)CC1)c1ccc(Br)cc1 +Cn1cnc(S(=O)(=O)Nc2cccc(C(c3c(O)c4c(oc3=O)CCCCCC4)C3CC3)c2)c1 +O=C(Nc1cc2c(cc1F)C(O)C(F)(F)CC2)c1cc2cc(Cl)ccc2[nH]1 +COc1ccccc1CCNC(=O)c1cc(-c2ccncc2)nc2ccc(Br)cc12 +NS(=O)(=O)NCCCCC(NC(=O)OCc1ccccc1)C(=O)Nc1nc(-c2ccccc2)cs1 +Clc1ccc2c(NCCCNc3ccnc(N4CCCCC4)n3)ccnc2c1 +Cc1ccc(N2C(=O)c3cccc4c(N)ccc(c34)C2=O)c2cccnc12 +O=C(Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)C1OC1CN1CCCCC1 +COc1cccc(C(=O)NC(CCCNC(=N)N)C(=O)NC(Cc2ccccc2)C(N)=O)c1 +CC(C)(C)Oc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +FC(F)(F)c1ccc(Nc2ncnc3sc(Nc4ccccc4Cl)nc23)cc1 +CC(C)c1csc2nc(N3CCC(COCCN4CCCC4)CC3)ncc12 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2ccccc2CN2CCN(C)CC2)cc1 +O=C1c2[nH]nc(NS(=O)(=O)c3cccc4ccccc34)c2CCN1C1CCNCC1 +Nc1ccccc1NC(=O)c1ccc(CNC2=NC(c3ccc(O)cc3)CO2)cc1 +NC(CCc1cc(F)cc(F)c1)(C(=O)O)C1CC1C(=O)O +CC1(C)c2nc(C(=O)NCc3ccc(F)cc3)c(O)c(=O)n2CCN1Cc1nnn[nH]1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NCCN(C)C)n1)C(C)(C)CN2 +CNc1nc(-c2ccccc2)[n+](-c2ccc(C)cc2)s1 +Cc1c(C(=O)NC2(c3noc(C(F)(F)F)n3)CC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +COc1ccc(C)c(N2CCN(Cc3ccc(F)cc3Cl)C(=O)C2=O)c1 +CC(C)(C)c1ccc(Oc2cccc(CCCC(P(=O)(O)O)S(=O)(=O)O)c2)cc1 +Cc1nc2cnc3ccc(C#CCNC(=O)c4cccn(C(CO)c5cccc(F)c5)c4=O)cc3c2n1C(C)C +O=S(=O)(Nc1nccnc1-c1ccc(COc2ccc(Cl)nc2)cc1)c1ccccc1C(F)(F)F +CC(C)(C)OC(=O)c1ncn2c1CN(C(=O)OC(C)(C)C)c1ccccc1-2 +CCCN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 +CCOC(O)=C1C(COCCNc2n[s+]([O-])nc2N)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +Cc1ccc(S(=O)(=O)N(CC(=O)Nc2ccc(C#N)cc2)c2ccc(F)cc2)cc1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(C#N)cc3)nc2n1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccc(CN2CCCCC2)cc1Cl +COc1ccc2cc(-c3c(-c4ccncc4)nc(-c4ccc(S(C)(=O)=O)cc4C)n3C)ccc2c1 +COCC(=O)NC1CCC(C(=O)N(C)c2ccc(-c3nc4ccccc4o3)cc2)C1 +COc1cc(-c2ccc3ncc(C(C)=O)c(NC4CCC(CN(C)C)CC4)c3c2)cc(Cl)c1O +Cc1cccc(-c2noc(C3CCCN3C(=O)c3ccc(C)s3)n2)c1 +CN(C)c1ccc(C=C2COc3ccc(Br)cc3C2=O)cc1Br +CC(C)OCCOc1nc(Oc2cc(F)c3c(c2)COB3O)c(Cl)cc1C#N +CC(=O)c1cn(C)c2ccc(Nc3nccc(-n4cc(CN5CC(O)C5)c(C)n4)n3)cc12 +O=C(Nc1cccc2c1OC(c1nnn[nH]1)CC2=O)c1ccc(OCc2ccc3ccccc3n2)cc1 +Cn1cc2c(nc(NC(=O)Cc3cccs3)n3nc(-c4ccco4)nc23)n1 +Cc1cc(S(=O)(=O)c2cncnc2)cc2c3c(n(C)c12)CC1CCC3N1 +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4CC5C(N)C5C4)cn3)nc2n1C1CCCC1 +O=C(Nc1ccc(N2CCN(C(=O)C3CCOC3)CC2)cc1)N1Cc2ccccc2C1 +CC(C)N(Cc1cn2c(N3CCN(C)CC3)cccc2n1)C1CCCc2cccnc21 +CCCNc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1Cl +CN(CCc1ccccc1)C(=O)Cc1cc(C=CC(=O)O)cc2c(-c3ccccc3)cccc12 +CCN1CCN(c2ccc(Nc3ncc(C)c(Nc4ccc5[nH]ncc5c4)n3)cc2)CC1 +O=C(c1cc(Cl)cc(Cl)c1)N1CCC(NCc2ccnc3ccccc23)CC1Cc1ccccc1 +Cc1cc(C)nc(NC(=S)N2CCN(c3ccc(C(F)(F)F)cc3Cl)CC2)c1 +CCOc1ccc(-c2cc(C(=O)O)c3cc(F)ccc3n2)cc1 +Cc1cnc(COc2ccc3nc(CC(C)(C)C(=O)O)n(Cc4ccc(OC(F)(F)F)cc4F)c3c2)c(F)c1 +O=C(Cn1c(-c2ncco2)cc2cc(F)ccc21)NCc1nc2ccccc2[nH]1 +COC(=O)Nc1ccc2c(c1)NC(=O)C(C)CCCC(N1CCC(c3cc(Cl)ccc3OC)=CC1=O)c1cc-2ccn1 +CC1C(c2ccccc2)C1(NS(=O)(=O)N1CCn2c(cc3cc(Cl)ccc32)C1)C(=O)O +Cc1ccc(-c2nn(CCN3CCN(c4ccccc4OC(C)C)CC3)c(=O)c3ccccc23)cc1 +CCCCN(CCCC)C(=O)c1nn(-c2ccccc2C(=O)N2Cc3ccccc3CC2CN)c(C)c1Cl +CC1CN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2F)CC(C)C1(O)c1cccc(C#N)c1 +CCCCCCC1C(=O)OC1C(=O)NCCCCC(NC(=O)C(C)NC(=O)OCc1ccccc1)C(=O)OCc1ccccc1 +CC(C)Nc1nc(-c2ccc(N3CCOCC3)nc2)cc2ncn(C)c(=O)c12 +O=C(CCCCCCCn1cc(-c2cccnc2)nn1)NCC(c1ccccc1)c1ccccc1 +CCN(CC)C(=O)c1ccc(C(=C2CC3CCC(C2)N3CCCc2ccccc2)c2ccccc2)cc1 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+O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2CCC(c3ccccc3)C1Cc1[nH]ncc12 +CCN(CC)c1ccc(C=NNc2c3c(nc4ccccc24)CCCC3)cc1 +c1cncc(CNc2csnc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c1 +CCCc1nc(C(=O)OCC)c2c(C)nc3ccc(OC)nc3n12 +COCCN(CCOC)c1nn2c(-c3cccc(Cl)c3)nnc2c2ccccc12 +CC(C)c1onc(C[S+]([O-])c2c(Cl)cccc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +N#Cc1c(C2CCCNC2)cc(-c2c(O)cccc2OCC2CCC2)nc1N +Cc1cc(Nc2ccc(Cl)cc2)n2nc(C(F)(F)F)nc2n1 +O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OCC2CCCC(F)(F)C2)cc1F +CN(CCCc1ccc(CN)cc1)CCNS(=O)(=O)c1ccc2ccccc2c1 +COc1cc(NC(=O)Nc2nccs2)cc(-c2cccnc2)c1OC +CCN(CC)C(=O)c1cccc(Oc2cccc(-c3c(C)cnc4c(Cl)cccc34)c2)c1 +CCCCCCCCCCCCCCCCNC(=O)C1(C)CC(c2ccc(C)cc2)=C(C(=O)Nc2ccc(OC)cc2)C(=O)N1 +O=C(Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1)Nc1cc(F)cc(N2CCOCC2)c1 +Cc1ccc(CC(C(=O)NCc2ccc(C(F)(F)F)nc2SC2CCCCC2)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1ccncc1C)Oc1ccc(F)cc1-3 +COCC(C)N1CCc2nc(C(=O)Nc3cc(C(=O)O)ccc3CNC(=O)c3ccc(Cl)s3)sc2C1 +CCC(CO)NC(=O)c1ccc(OCc2c(-c3ccccc3)noc2C)nc1 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+Cc1noc(C)c1-c1ccc2c(c1)C(c1ccccc1)(N1CCC(NC(=O)OC(C)(C)C)C1)C(=O)N2 +Cc1cc(CN2CC(N)C(C(=O)C3CCCC3C#N)C2)ccc1C#N +O=C1NCCN1CCN1CCCC(c2c(-c3ccccc3)[nH]c3ccccc23)C1 +O=C(OCOCCN1CCOCC1)C1(c2ccc(Cl)c(Cl)c2)CCCCC1 +O=C(O)CC1Nc2cc(C(=O)NCCC3CCNCC3)ccc2CN(CCc2ccccc2)C1=O +O=C(O)Cc1cnc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1cccc(F)c1 +COC(=O)C1CC2(CN1S(=O)(=O)c1ccc(C)cc1)OCCO2 +C#Cc1ccc2c(c1)-c1nc(C)ncc1Cc1c(C(=O)OCC)ncn1-2 +COc1ccccc1-c1ccc2c(c1)C(C(C)OCCCc1ccccc1)=CC(C)(C)N2 +Cc1cc(CC(OC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2ccccn2)cc2c(Cl)n[nH]c12 +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(C2CCC(O)CC2)sc2cc(O)ccc12 +c1cc(-c2cnc3c(-c4ccsc4)cnn3c2)ccn1 +CN1Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4CC5)c(F)c3)cc2C1 +COc1cc2nc(N(C)CCCCCCNC(=O)c3ccco3)nc(N)c2cc1OC +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(CCO)CC4)ncn3)c2c1 +CN1C2CCC1CC(OC(=O)c1cc(=O)n(C)c3ccccc13)C2 +CC1(C)CCc2[nH]c3cc(Cl)ccc3c(=O)c2C1 +COc1ccccc1N1CCN(CCCCN2C(=O)Cc3ccccc32)CC1 +Nc1nnc(-c2ccc3[nH]cc(-c4cccc(-n5cccn5)n4)c3c2)o1 +CN1CCCN(c2ncc3ncnc(Nc4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4Cl)c3n2)CC1 +CNC(=O)Cn1cc(-c2cnc(N)c3c(-c4cccc(C(=O)Nc5ccccc5)c4)csc23)cn1 +Cc1nc(N)ccc1CNC(=O)Cn1c(C)cnc(NCCc2ccccc2)c1=O +CC1CN(c2ccc(Cl)cc2)C(=O)c2cc(COc3ccc(F)cn3)nn21 +O=C(O)C(Cc1ccc(-n2c(-c3cccnc3)nc3cccnc32)cc1)NC1=C(Cl)C(=O)C12CCCCC2 +CS(=O)(=O)c1ccc(C2C(Oc3ccccc3)C(=O)N2c2ccc(F)cc2)cc1 +NC(=S)NN=C(C=Cc1ccccc1)c1ccc(Cl)cc1 +CCCCCCOc1ccc2ccn(CCC(CO)n3cnc(C(N)=O)c3)c2c1 +CC1(C)Cc2c(c(-c3ccco3)nc3sc4c(NCCCO)ncnc4c23)CO1 +O=C(Cc1ccsc1)N1CC=C(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +Nc1ccc(Cn2ccnc2)c2c(=O)c3ccccc3oc12 +CC1C(Nc2ccc(Br)cn2)CCCN1C(=O)c1ccccc1-n1nccn1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cn(CCN2CCOCC2)c2ccccc12 +CC12CCC3C(CCC4CC5(CCC43C)CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)CC(=O)O5)C1CCC2=O +COc1cc(-c2nn(C(C)C)c3ncnc(N)c23)cc(OC)c1OC +CC12CCC(O)CC1=CCC1C2CCC2(C)C1CCC2n1ccnc1 +CCCCC(C=NNC(=O)N1CCCc2ccccc21)NC(=O)OC(C)(C)C +O=C(C=Cc1cccc(S(=O)(=O)N2CCN(c3ncccn3)CC2)c1)NO +NC(=O)c1cccc2c1C(=O)N(C1CCN(Cc3cccc(Cl)c3)CC1)C2 +NCCCNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C(NC(CO)c1ccc(F)c(Cl)c1)N1CCc2cnc(NCCO)nc2C1 +O=C(NCc1cccc(O)c1)C(=O)c1c[nH]c2ccc([N+](=O)[O-])cc12 +CCCOc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(OC(F)(F)F)c2)c1 +O=C(C1=C(Nc2cccc(Br)c2)C(=O)N(CCCn2ccnc2)C1c1ccc(Br)cc1)c1ccccc1 +CC(C)(Cc1ccc(OC(F)(F)F)cc1)NCC(O)c1ccc(O)c2c1OCC(=O)N2 +CCOC(=O)c1cnn(CC(C)O)c1NC(=O)N1CCN(Cc2ccccc2)CC1 +CCNc1cc(N2CCNCC2)ccc1S(=O)(=O)c1ccccc1 +CCCCCCCOc1ccc(-c2ccc(C(=O)O)cc2)cc1 +O=C(NCc1ccccc1F)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CCN(CC)C(=O)c1cccc(Oc2ccc(-c3nc4cc(C(N)=O)ccc4[nH]3)cc2)c1 +Cc1oc(-c2ccccc2)nc1CCOc1cccc(CC2C(=O)N(c3ccc(Cl)cc3)C2C(=O)O)c1 +CCC(=O)N(Cc1cccc(OC)c1)c1cc(F)cc(-c2nnn[nH]2)c1 +CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)C(C)c2cc(F)ccc2Cl)ccc1Oc1ccc(F)cc1F +FC(F)(F)c1cccc(N2CCN(CCCCNc3ccc(-c4ccccc4)cn3)CC2)c1 +CN1CCN(c2ccc(Nc3nc4c(-c5cccc(CN(C)S(C)(=O)=O)c5)cccn4n3)cc2)CC1 +O=C(CCc1ccccc1)c1ccc(OCC(O)CN2CCCCC2)cc1 +O=C(NCc1cnc[nH]1)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +CC(=O)N(C)CCCn1c(-c2ccccc2)cc(C(=O)Nc2cccc(C(F)(F)F)c2)c1C +Cc1cc(Br)cc(C(=O)NO)c1N(C)S(=O)(=O)c1ccc(Oc2ccc(C(C)(C)C)cc2)cc1 +COc1cc2c(Nc3ccc(Sc4nccn4C)c(Cl)c3)c(C#N)cnc2cc1C=CCCO +Cc1c(CC(=O)O)c2cc(Cl)ccc2n1C(=O)c1ccc(OCC2CN(C)c3ccccc3O2)cc1 +CC(=O)Nc1ccc(-c2ncnc3c2cc(C(=O)OCc2ccccc2)n3C)cc1 +COc1cc(-c2ccncc2NC(=O)c2nc(-c3c(F)cccc3F)ccc2N)cc(N)n1 +O=C(O)CCCCCc1ccn2cc(-c3ccc(-c4ccccc4)c(C(F)(F)F)c3)nc2c1 +Cc1ccn2c(CC(=O)O)cc(-c3ccc(C(F)(F)F)cc3Cc3c(C)noc3C3CC3)c2n1 +O=C(Nc1ccc(F)c(-c2nc3ncc(Br)cc3o2)c1)c1ccco1 +Cc1n[nH]c(C)c1-c1nc(NCCN)c2c3c(sc2n1)CCCC3 +[C-]#[N+]c1cccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)c1C +Cc1cc(C#N)cc(C)c1Nc1nc(Nc2ccc(C#N)cc2)ncc1Br +O=C(c1cccc(F)c1-n1nccn1)N1CC2CN(c3ncc4cc(F)c(F)cc4n3)CC2C1 +NCC1CCC2C(c3ccccc3)Nc3ccc(C(F)(F)F)cc3C2O1 +Nc1cccc(C#Cc2cccc(C(=O)N3CCN(c4ccccn4)CC3)c2)c1 +CCCCc1nn2c(-c3ccccc3)cnc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cc(OC)cc(C(=O)N(CCCc2ccccc2)Cc2ccc(-c3ccccc3CCC(=O)O)cc2)c1 +CC(C)(C)c1ccc(C[N+](C)(C)CCCN2c3ccccc3Sc3ccc(Cl)cc32)cc1 +O=C(NN=Cc1ccccc1O)c1cc(-c2ccc(Cl)cc2)nn1Cc1ccc(Cl)nc1 +CC1SC(C)(C)C(=O)N1CCCCN1CCN(c2csc3cc(Cl)ccc23)CC1 +CNC(C)C(=O)NC(CCC(N)=O)C(=O)N1CCCC1C(=O)NC(c1ccccc1)c1ccccc1 +O=C(O)C1=Cc2cc(Cl)cc(-c3ccc(F)cc3)c2OC1C(F)(F)F +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1C(CC#N)COc1ccccn1 +CCCNc1ncc(-c2ccc(F)cc2)cc1C(=O)c1ccc(F)cc1 +Cc1cc(C(=O)O)c(-n2[nH]c3c(cnc4ccccc43)c2=O)s1 +CCN(CC)CCOC(=O)C(CC)(c1ccccc1)c1ccccc1 +COc1ccc2c(c1)CN(C(=O)N1CCCCC1)CCS2 +CC(c1ccc(-c2cnc(N)nc2)nc1)(c1noc(-c2cnn(CC#N)c2)n1)C1CC1 +Cc1c(C(O)CN2CCC3(CC2)CC(=O)N(c2ccc(C#N)cn2)C3)ccc2c1COC2=O +CCCCS(=O)(=O)Oc1ccc2c(C)c(C#N)c(=O)oc2c1 +NC(=O)C(CC(O)C(Cc1ccccc1)NC(=O)c1cnc2ccccc2n1)C1CCCCC1 +CCC(NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(Cl)ccc34)nc12)C(=O)N1CC(C#N)C1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(OC4CC4)cn3)C2)cc1 +CN1CC=C(c2c[nH]c3ccc([N+](=O)[O-])cc23)CC1 +Cc1c2c(=O)n(-c3ccccc3)nc-2n(CC(=O)N(C)c2ccc(Cl)cc2)c2ccccc12 +CCCC=Cc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +COc1cc(N2CCCN(C(C)=O)CC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 +CN1CCN(CC(=O)N2CCc3cccc4c3C2CNC4=O)CC1 +CNC(C)C(=O)NC(C(=O)NC1CCCN(CCc2ccc([N+](=O)[O-])cc2)C1)C(C)(C)C +O=C(O)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 +CCn1cnc2c(-c3ccc(Cl)c(-c4ccc(S(=O)(=O)CC)cc4OC)c3)cnnc21 +CCc1cccc(C(=O)N(CC)c2ccnc(NC(C)c3ccccc3)n2)c1 +O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1CCCc2cc(-c3cccnc3)ccc21 +COc1ccc(C=CC(=O)NC(=O)c2ccccc2O)cc1 +CC(C)N1CCC(Oc2ccc(C(CCN(C)C)Oc3ccccc3)cc2)CC1 +CC1CN(c2ncc(F)cn2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +O=C(O)COc1cccc(CCn2ncc(-c3ccccc3)c2-c2ccccc2)c1 +CC(O)C1CCN(c2ccc(Cl)cc2NC(=O)c2cnn3cccnc23)CC1 +COc1cc(C=C2SC(=O)N(CC(=O)Nc3ccccc3F)C2=O)cc(Cl)c1O +CCCCc1nnc(SCc2ccccc2C#N)n1Cc1ccc(NC(=O)c2ccccc2C(=O)O)cc1 +COc1ccc(CNc2nc(N3CCCCCC3)nc3c2ncn3C(C)C)cc1 +O=C1C2CCCCN2C(=O)N1CCN1CCN(c2cccc(Cl)c2)CC1 +CCC(=O)NC1CCC(C(=O)N(C)c2ccc(-c3nc4ccccc4n3C)cc2)C1 +COc1cc(NC(=O)Nc2ccccn2)cc(-c2cccnc2)c1OC +COc1cc(OCc2cccc(-c3cncnc3)c2)c2cc(-c3cn4nc(C(C)(F)F)sc4n3)oc2c1 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+Nc1c(N(CCC2=CCCCC2)C(=O)c2ccc([N+](=O)[O-])o2)c(=O)[nH]c(=O)n1Cc1ccccc1 +COc1ccc2c(c1)C(N1CCN(C(=O)C3CC3)CC1)CCC2 +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(Cc1ccccc1)N=Cc1cnn2ccc(C#N)cc12 +CCCS(=O)(=O)Nc1cc(F)cc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC)n2)c1Cl +COc1cc(C(=O)c2ccc(-c3csc(NC(=O)C(N)Cc4ccccc4)n3)cc2-n2cncn2)cc(OC)c1OC +O=C(CN1CCN(c2c(Cl)cnc3[nH]c(-c4ccc(CN5CCOCC5)cc4)nc23)CC1)Nc1nccs1 +Cc1c(S(=O)(=O)Nc2cccc(-c3nnn[nH]3)c2)sc2ccc(N)cc12 +Cc1cccc(-c2oc(C)nc2C(=O)Nc2cnn(Cc3nc(C(C)(C)O)co3)n2)c1 +O=C(Nc1ccc(OCCN2CCOCC2)c(F)c1)c1cccc(-c2cccc(O)c2)c1 +CC(O)C(=O)N1CCC(n2c(=O)n(C)c3cnc4ccc(-c5cnc6[nH]ncc6c5)nc4c32)CC1 +Cc1cc(-n2ccc(=O)cc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +COc1ncccc1C(C)c1c(CCN(C)C)sc2ccccc12 +C=C(C)C1CCC2(C(=O)NCCCCCO)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CCc1nc(Nc2ccc(C#N)c(OCC=C(C)C)c2)nc(OCCOC)n1 +CN(C)Cc1cc(C=NN=C(N)CC(O)c2cc3ccccc3c3ccccc23)ccc1O +CC(C)(c1ccccc1)N1C2CCC1CC(Oc1cccc(C(N)=O)c1)C2 +COc1ccc(Cl)cc1N1CCN(CCN2C(=O)C3Nc4ccccc4C3N=C2C)CC1 +O=C(NCc1cccc(-c2cccc(CN3CCNCC3)c2)c1)c1cccc(C(F)(F)F)c1 +CC(C)C(O)CNc1cc(-n2ncc3cc(Cl)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(Br)c4)c(C)c3)c2cc1OC +Oc1c(Cl)cc(SSc2cc(Cl)c(O)c(Cl)c2Cl)c(Cl)c1Cl +COC(C)(C)c1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1 +CCc1cccc(N(C)C(=N)Nc2cc(C(F)(F)F)cc(CC)c2Cl)c1 +OC(c1ccccc1)(c1ccccc1)C1CCN(CCCOc2ccc(-c3ccccc3)cc2)CC1 +CON=C(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(CCN1CCN(C)CC1)c1ccc(Cl)c(Cl)c1 +CC1=C(C#N)C(C)(c2ccc(F)cc2)C(C(=O)OC(C)(C)C)=C(C)N1 +N=C(N)c1cc2cc(-c3cccc(OCc4ccc(F)c(Cl)c4)c3)ccc2s1 +COCCCc1cccc2cccc(CN(C(=O)C3CNCCC34OCc3cc(F)c(F)cc34)C3CC3)c12 +O=S(=O)(Nc1ccncn1)c1ccc2c(-c3ccc(C(F)(F)F)cc3C3=CCNCC3)cccc2c1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NCc1cnco1 +CCOC(c1ccccn1)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +Fc1ccccc1-c1nc2cnn(Cc3cc(-c4ccc(Cl)cc4)no3)cc-2n1 +Cc1ccc2c(-c3nnc(SCCCN4CCc5nc6cc(C(F)(F)F)ccn6c5CC4)n3C)cccc2n1 +CS(=O)(=O)Nc1cccc(-c2ccc3nc(NC(=O)C4CCCCC4)nn3c2)c1 +Nc1nc(CNC2CCCN2Cc2ccnc(Cl)c2)nc2nc(-c3ccco3)nn12 +O=C(CN1CCC(NC(=O)c2ccc(Cl)s2)C1)Nc1ccc(-n2ccccc2=O)cc1F +CC(C)(C(=O)N1CCC(CC(=O)O)CC1)C(O)C=Cc1ccc(C(=N)N)cc1 +O=C(c1ccc(F)cc1)c1cc2n(c1)CCN(CCc1ccc(CN3CCCCC3)cc1)C2=O +C=C1C(=CC=C2CCCC3(C)C(C(C)CC[S+](=N)([O-])c4ccccc4)=CCC23)CC(O)CC1O +C=CCCCC(OC(=O)C1CCCCN1C(=O)C(=O)C1(O)OCCCC1C)C(C)=CC1CCC(O)C(OC)C1 +c1ccc2c(c1)OCC(c1nc3ccc(-c4ccncc4)cc3n1CCN1CCOCC1)O2 +CC(C)C(C(=O)NO)N(CCn1cc(CNS(=O)(=O)c2ccc(F)cc2)nn1)S(=O)(=O)c1ccc(OCCF)cc1 +CC(C)C(NC(=O)c1ccc2c(c1)OCCO2)C(=O)N(C)N(C#N)Cc1ccccc1 +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(N3CCc4ncsc4C3)c2cn1)c1ccc(F)cc1 +Cc1nc(N)nc(-n2c(Nc3cc[nH]n3)nc3cc(F)c(F)cc32)n1 +N#Cc1cccc(S(=O)(=O)Nc2ccc(Oc3ccccc3)cc2)c1 +O=C(CN1C2=NCCCN2c2ccccc21)c1ccc([N+](=O)[O-])cc1 +NCC1CCC(C(=O)NC(Cc2ccccc2)c2nc(-c3ccc(C(N)=O)cc3)c[nH]2)CC1 +CC(=Cc1ccc(C)cn1)C1CC2OC2(C)CCCC(C)C(O)C(C)C(=O)C(C)(C)C(O)CC(=O)O1 +NS(=O)(=O)c1ccc(CCNC(=O)c2ccccc2S)cc1 +Cc1cc(C#N)ccc1-c1ccnc(NCc2n[nH]c3nc(N)ccc23)c1 +O=c1[nH]c(C2CCN(C3CCCCC3)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +Clc1cccc(CN2CCCC(Nc3cccc4cnccc34)C2)c1 +CCOc1ccc(C#Cc2ccc(CC(C)NC(C)=O)cc2)nc1 +C=C(C)C1CCC2(COC(=O)n3ccnc3)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC(C)c1c(-c2nnc(CN3CCC(O)C3)o2)cn2ncnc(Nc3cc(C(=O)NC4CC4)c(F)cc3F)c12 +CCCCc1nc(SC)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(N)(=O)=O)cc1 +N#Cc1cc(Cl)cc(-c2cc(-n3cc(F)cn3)ncn2)c1 +O=C1C(c2c(O)[nH]c3ccc(Cl)cc23)=Nc2ccccc21 +CN(C(=O)c1ccccc1-c1nc2cc(-c3cnc(N)nc3)ccc2n1C(C)(C)C)c1ccccn1 +CC1CCC(NC(=O)c2cc3cccnc3n(CCCCF)c2=O)CC1 +CC(Nc1nc(N)nc(NCCc2ccc(F)cc2)n1)c1ccc(F)cc1 +CNC(=O)c1cccc2c1nc(Nc1ccccc1Cl)c1ccncc12 +CC(C)(c1cc(-c2cccc(-c3ccc[n+]([O-])c3)c2)c2ncccc2c1)S(C)(=O)=O +O=C(c1csc2ccccc12)N(CCc1ccc(Cl)cc1)C1CCC(O)CC1 +COc1cc(OCc2csc(C3CCC(F)(F)CC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +CCCCCNC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)CC1CCCCC1 +c1cc(C2CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)ccc1OCCN1CCCC1 +O=C1CCCc2cc3c(cc2N1)[nH]c1cc(C(F)(F)F)ccc13 +COc1ccc2c(nc(Nc3c(C)cccc3C)c3cncn32)c1OC +Cc1cccc(NC(=O)c2nc(C)n(-c3ccc(Cl)cc3)c2C)n1 +CCCCOc1ccccc1-c1ccc(N=Nc2cc(S(=O)(=O)O[Na])c3ccccc3c2N)cn1 +COC(=O)c1c(F)cccc1-c1ccc(CNc2ccc(C(=O)N3CCOCC3)cn2)c(F)c1 +CCCOc1ccc(-c2nc(-c3cccc4c3CCN4CC(N)(CO)CO)no2)cc1Cl +Cc1cccc2cc(Cn3nc(-c4cc(O)cc(F)c4)c4c(N)ncnc43)n(-c3ccccc3Cl)c(=O)c12 +CN1CCC(c2cc3c(-c4cccc(NCCN5CCOCC5)n4)ccnc3[nH]2)CC1 +NC1=NC(CCc2ccc(Nc3cccc4cccnc34)cc2)CO1 +O=C(O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2Oc2ccccc2OC(F)F)cn1 +COc1ccc(C(=O)CCC(=O)NNC(=O)Cn2c(C)nc3ccccc32)cc1 +CN1CCC23c4c5ccc(O)c4OC2C(OC2C=CC(O)C(C(=O)O)O2)C=CC3C1C5 +Cc1ccc2c(C)c(N(Cc3ccc(OC(F)(F)F)cc3)S(=O)(=O)c3ccc(C(=O)O)cc3)ncc2c1 +Cc1ccc(Cn2nc3c(C(F)(F)F)cccc3c2-c2ccc(F)cc2)c(C)c1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cc2ccccc2n1CCCCCO +Cc1cccc(NNC(=O)C(=O)c2c[nH]c3ccccc23)c1 +Cn1cc(C=CC(=O)NS(=O)(=O)c2ccc(F)c(F)c2)c2c(Oc3ccc(Cl)c(Cl)c3)cccc21 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2ccc(C(C)N(C)O)nc12 +Cc1nc(-c2nc(N)[nH]c2-c2ccc3nccnc3c2)ccc1F +CC1CCCCN1CCOc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccc(Cl)s1 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+CCc1nc(C=Cc2cccc(C(CCc3ccccc3C(C)(C)O)SCC3(CC(=O)O)CC3)c2)ccc1C(F)(F)F +CN(C)CCN(Cc1ccc(Cl)c(Cl)c1)C(=O)c1cc2scc(C(F)(F)F)c2n1-c1ccc(F)cc1 +Oc1ccc(CC2(O)COc3c(ccc(O)c3O)C2O)cc1O +O=C(Nc1ccc(Nc2nc(Nc3ccc(O)cc3)ncc2F)cc1)c1ccccc1F +COc1ccc(C(O)(c2ccc3nc(Cl)c(Oc4ccccc4)c(Cl)c3c2)c2cncn2C)cn1 +COc1cccc(NC(=O)N2CCOC(CN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 +COC1c2ccccc2CC1Oc1cc(OC2CC(O)C(COS(N)(=O)=O)C2)ncn1 +COc1ccc2c(c1)-c1c(ccn1CC(C)N)C2(C)C +CCCCS(=O)(=O)NC(=O)C1=CC(OC(CC)CC)C(NC(C)=O)C(NC(=N)N)C1 +O=C1C(=O)N(CCc2ccc(Br)cc2)c2c(Br)cc(Br)cc21 +CCc1ccc(C(=CCC(N)C(=O)O)c2ccc(F)cc2F)cc1CC +CON=C(C)c1ncn2c1COc1c(CCN3CCN(c4cccc5nc(C)ccc45)CC3)cccc1-2 +COc1cc(C(=O)c2nc(-c3ccccc3)cn2C2CCCC2)cc(OC)c1OC +C#CCCOc1ccc(OC)cc1CCNC(=S)Nc1ccc(Br)cn1 +O=S(=O)(NCCO)c1ccc(-c2cnc(N3CCOCC3)c3nc(C=Cc4ccc5ccccc5n4)cn23)cc1 +CC(C)Oc1ccccc1N1CCN(C2CCC(NC(=O)Nc3ccc(F)cc3F)CC2)CC1 +C=CCn1nc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)c1C(F)(F)F +CN1C(=O)N(c2cc(Cl)cc(Cl)c2)C(=O)C12CN(c1ccc(-c3nnn[nH]3)cn1)CC2c1ccc(C#N)cc1 +CCOc1ccc(CC(NC(=O)c2ccccn2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)c(F)c2)cc1 +COCC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(C)C(=O)C4)ncn3)c2c1 +OCC1CC(n2nnc3c(NC4CC4c4ccccc4)nc(SCCC(F)(F)F)nc32)C(O)C1O +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)OC2COCCOCCOC2)cc1 +COCCOC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)C)C1c1cccc([N+](=O)[O-])c1 +CCCCc1nc2ccccc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CN(C)c1ccc(C(=O)NCCCCNc2c3c(nc4ccccc24)CCCC3)cc1 +Clc1ccc(CSc2nnc(-c3ccccn3)n2Cc2cccnc2)cc1Cl +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(C4CCOCC4)C3)cc12 +O=C(Nc1cccnc1)C1CC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C(O5)C1=O +CS(=O)(CCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1)=NC#N +N#CC1CCCN1C(=O)CNCCN1CCN(c2ccccc2)C1=O +Cn1c(=O)c2cnc(Nc3ccc(C(=O)O)cc3)nc2n1-c1ccccc1 +COc1ccc(-c2c(-c3ccncc3)nnn2CC(=O)Nc2ccc(-c3ccccc3)cn2)cc1 +CSCCNCC(C)(C)c1ccc(NC(=O)c2nc(C#N)c[nH]2)c(C2=CCC(C)(C)CC2)c1 +O=C(NCC1CCN(CCCS(=O)(=O)N2CCN(c3ccc(F)cc3)CC2)CC1)c1cccc2c1OCCO2 +Cn1cnc2cc(-c3ccc(N4CCC(O)C4)c(S(C)(=O)=O)c3)nc(N3CCC(CO)C3)c2c1=O +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(c2nnn[nH]2)CC1 +CN(C)Cc1ccccc1NC(=O)OCC(Oc1cccc2sc(C(=N)N)cc12)c1ccccc1 +O=c1[nH]c2ccccc2n1C1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +NC(=O)c1sc(-c2cnc3ccccn23)cc1OCc1ccccc1C(F)(F)F +COc1ccc(C(=O)Nc2nc3ccc4nc(C)sc4c3s2)cc1 +CN(C)CCCN=C1CC(c2ccc(Cl)cc2Cl)CC2Nc3ccc(Cl)cc3C(=O)C12 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN(C(=O)c2ccccc2)c2ccc(C)cc2)cc1 +Cc1cn2nc(C3CCCCN3C(=O)c3cc(Cl)ccc3NS(C)(=O)=O)cc2nc1N1CCCC1 +CS(=O)(=O)N1CCCC(Nc2nc(N)ncc2-c2cnc3[nH]ccc3n2)C1 +CCSCC1(C(=O)Nc2ncc(-c3ccccc3S(N)(=O)=O)cn2)CC(c2cccc(C(=N)N)c2)=NO1 +CC1(C)CC2CC(C)(CN2C(=O)c2ccc(-c3ccc(-c4cccc5cccnc45)c(Cl)c3Cl)cc2Cl)C1 +COc1ccc(S(=O)(=O)N2CCc3cc(Br)cc(NC(=O)c4ccco4)c32)cc1 +CCOC(=O)C(O)c1cc(-c2ccc(S(C)(=O)=O)cc2)n(-c2ccc(OC)cc2)c1C +COc1cc(CN2C(=O)N(Cc3ccc(O)c(OC)c3)N(C(=O)CC3CCCC3)CC(O)C2Cc2ccccc2)ccc1O +O=C(NC1(c2ccc(Cl)cc2)CC1)c1nn(-c2ccccc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1 +COc1cc(N2CCN(C)CC2)ccc1Nc1cc(-c2c[nH]c3cnccc23)ncn1 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+O=C(CCCCCCC(=O)c1ncco1)Nc1cc2ccccc2[nH]1 +CN1CCc2c(sc(NC(=O)c3ccc([N+](=O)[O-])o3)c2C(N)=O)C1 +Nc1cc(-c2cccc(NCc3cccc(F)c3)n2)c(Cl)cn1 +O=C(O)C(Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1 +CC(C)(CNC(=O)C1(C#N)CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +COc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccc(S(C)(=O)=O)cc3)s2)cc1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)C1CCCNC1)C2 +CC1CC2=CC(=O)CCC2C2CCC3(C)C(CCC3(C)O)C12 +CCN(CC)c1ccc(C)c2nc(-c3c(OC)cc(COC)cc3OC)c(C)cc12 +O=C(Nc1nc2c(s1)CC(N1CCOCC1)CC2)c1cccc(C2CCCN2C(=O)c2cc(-c3ccncc3)[nH]n2)c1 +Cc1cccc(C#CC2(O)CC3CCC(C2)N3C(=O)C(C)(C)C)c1 +CC(CN1CCC2(C)CC1Cc1c(O)cccc12)OCc1ccccc1 +CNC(C)C(=O)Nc1cc(-c2nn(C)c3ncnc(N)c23)cc(NC(=O)c2ccccn2)n1 +Cc1cccc2c1S(=O)(=O)c1c(C)cccc1C2=O +Cc1nc(-c2ccc(OCC(C)C)c(C#N)c2)[se]c1C(=O)O +CCOC(=O)COCc1ccc(-c2ccc(CCN3CCCC3C)cc2)cc1 +Cc1cc(S(=O)(=O)NCc2cccs2)cnc1-c1ccc(N(Cc2ccccc2)C(=O)c2ccc(O)cc2O)cc1 +COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)NCCN(C)C)c1=O +CC1(C)CCC2=C(C1=O)C(c1ccc(F)c(Br)c1)C1=C(CCS1(=O)=O)N2 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc2c(ccn2S(=O)(=O)c2cccc(C(=O)O)c2)c1 +O=c1[nH]c2ccc(Cl)cc2n1S(=O)(=O)Cc1ccccc1 +COc1cc(Nc2nc3cccc(-c4ccc(NS(C)(=O)=O)cc4)c3o2)cc(OC)c1OC +CC(C)NC(=O)c1sc2ncnc(N3C4CCC3CC(N3CCCC3)C4)c2c1-c1ccccc1 +NCC(NC(=O)c1cc(-c2ccnc3[nH]ccc23)cs1)c1ccccc1 +CN(C)C12CC(OC(=O)CCN3CCCC3)C(C(c3ccccc3)C1)C(c1ccccc1)C2 +Cc1nnsc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C)cc1 +CN(c1ncc(Br)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +O=S(=O)(c1ccccc1)c1cnc2cc(-c3ccc(Cl)cc3)nn2c1-c1ccccc1 +Cn1nnnc1CNC(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1 +Cn1c(C2COCC2O)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O +Nc1nc(-c2cncnc2)cn2nc(-c3ccco3)nc12 +O=C1C2=C(C(=O)c3ccccc31)C1(CS2)NC(=O)C(Cc2ccc(O)cc2)NC1=O +O=C(CCCCCC(=O)NCc1cc(C(=O)NCc2ccccc2)c2cc(Br)ccc2n1)NO +Cc1ccc(C(=O)O)c(Oc2nc(Oc3cc(O)cc(-c4cccc(CN)c4)c3)c(F)cc2F)c1 +NC(=O)N1CCCc2cc(-c3cncc(-c4cccc(S(=O)(=O)NCCO)c4)c3)cnc21 +CNCC(Cc1ccccc1)N(C)CC(Cc1ccc(O)cc1)N(C)CC(Cc1ccc(O)cc1)N(C)C 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+Cc1cc(F)cc(C)c1N1CCN(Cc2cccc(C(F)(F)F)c2Cl)C(=O)C1=O +CCC(CC)C(=O)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)Cc1ccccc1 +CCc1c(Sc2ccccc2)n(OC(C)C)c(=O)[nH]c1=O +Cc1ncc(-c2ccnc(Nc3ccc(N4CCN(C(=O)CO)CC4)cc3)n2)n1C(C)C +O=C(Cc1c[nH]c2ccccc12)Nc1ncc(C2CCC2)s1 +O=S(=O)(c1ccc(C=Cc2ccccc2F)nc1)c1ccccc1F +c1ccc(-c2ccc(CNCCCNCc3ccc(-c4ccccc4)cc3)cc2)cc1 +COc1cc2c(c(OC)c1OC)-c1ccc(SC)c(=O)cc1C(NC(=O)C(N)c1ccccc1)CC2 +O=C(O)CC(O)CC(O)CCn1c(C(F)(F)F)nc(-c2cccs2)c1-c1ccc(F)cc1 +CN1C2CCCC1CC(NC(=O)n1c(=O)n(C)c3ccccc31)C2 +CCC(=O)OC1=C(c2ccc(OC)cc2)Sc2ccccc2-n2cccc21 +Clc1ccc(-c2cc(Cl)cc3c2N2CCNCCC2C3)c(Cl)c1 +O=C1OCC2C1Cc1ccc(F)cc1C2C=Cc1ccc(-c2cccc(Cl)c2)cn1 +CCN1C(=O)c2c(nc(C(=O)OC)n2Cc2ccc(OC)cc2)N2C1=NC1CCCC12 +c1ccc(CCN2CCC(c3cc(-c4cccs4)[nH]n3)CC2)cc1 +CS(=O)(=O)Nc1ccc([N+](=O)[O-])cc1Oc1ccccc1 +CC(C)C1N=CC(=NOc2ccccc2)N1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +CC(Oc1cccc(Cl)c1)C(=O)N(Cc1ccc(Cl)cc1)CC1CCCN1 +COC12C(COC(N)=O)C3=C(C(=O)C(C)=C(Nc4ccc(Br)cc4)C3=O)N1CC1NC12 +COc1ccc(-c2nc(C(C)(C)C)sc2CN2CCC3(CC2)CN(c2ccc(C(=O)O)cc2)C(=O)O3)cc1 +COc1ccc(C(=O)NCC(c2cnc(C(F)(F)F)nc2)N2CCC(F)(F)CC2)c(Cl)c1OC +C=C(c1ccc(OC)cc1)c1nc(C)cc2ccccc12 +CC(=O)Nc1cc(S(=O)(=O)Nc2ccc(F)cc2F)cc2c1N(CCc1ccc(F)cc1)CC2 +CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCC(N(C)C)C4)nc3)c2n1 +C[N+](CCCl)(CCCl)Cc1sccc1[N+](=O)[O-] +Cc1ccc(-c2cc(C(=O)NC(C)c3cnccn3)cc(N3C(=O)Cc4ccccc43)c2)cc1 +Oc1nc(SCCCCCCCCCc2ccccc2)ncc1Cc1cccnc1 +NC(=O)c1[nH]c2ccccc2c1S(=O)(=O)c1cc(Cl)ccc1N +CCCCc1nc2ccc(NCc3ccccc3)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCOC(=O)c1nc2c(O)nc3cc(Cl)c(-n4cnnc4)cc3n2n1 +CC(C(=O)OC1C[N+]2(CC(=O)Nc3cccc(F)c3)CCC1CC2)(c1cccs1)N1CCCCC1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2cc[n+]([O-])cc2)c1F +Cn1c(=O)c2nc(C=Cc3cc(F)cc(F)c3)[nH]c2n(C)c1=O +COc1cc2c(OCC3NC(=O)C4CC34)nccc2cc1C(N)=O +FC1(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CCNCC1 +CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCC(F)(F)CC2)n3S(=O)(=O)c2ccc(F)cc2)CC1 +Clc1ccc2c(Nc3ccc(Nc4nc(NCc5ccccc5)nc(N5CCCCC5)n4)cc3)ccnc2c1 +COc1cc(OC)c2c(c1CO)CC1c3cc4c(cc3CCN1C2)OCO4 +Cc1cc(C)c(S(=O)(=O)NC(C)CNc2cc(C)cc3c2cnn3-c2cccc(NC(C)C(N)=O)c2)c(C)c1 +COc1nccc2ccc(C(=O)N3CCC4(CC3)Cc3cn(C(C)(C)C)nc3C(=O)N4)cc12 +Cn1cc(S(=O)(=O)NCCOc2cccc(C(Cc3ccccc3)CN3CCCC3)c2)cn1 +CN(CC1CCCc2cc(S(=O)(=O)c3cccc(F)c3)ccc21)C(N)=O +COc1ccc(Cl)cc1CNC(=O)NC(Cc1ccccc1)c1nc(-c2ccc3c(N)n[nH]c3c2)c(Cl)[nH]1 +COc1ccc(C(Cc2ccccc2)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)cn1 +COc1ccc(OC(F)(F)F)cc1Cn1c(C(=O)NCC(C)(C)O)cc2cc(C#N)ccc21 +Cc1nc2cc(NC(=O)c3ccc([N+](=O)[O-])s3)ccc2s1 +NS(=O)(=O)c1ccc(NC(=O)NS(=O)(=O)c2ccc(Cl)cc2)cn1 +Cc1nc2cnc3cc(F)c(-c4ccc(Oc5cccc(CO)n5)cc4Cl)cc3c2n1C1CCN(C(=O)CO)CC1 +N#Cc1ccc(C2CCCCc3cncn32)c(-c2ccc(F)cc2)c1 +CCCN(CCN1CCN(c2ccccc2)CC1)C1CCc2ccc(NS(=O)(=O)c3ccc(C)cc3)cc2C1 +CC(=O)N1CCOc2cc(-c3cncc(F)c3)cnc21 +Nc1ncc(-c2ccc(C3(c4noc(-c5ccc(N6CCCC6CO)nc5)n4)CCC3)cn2)cn1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(F)c2)CC1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(-c3cncnc3)c2n1 +COc1cc(CCC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1OC +Cc1c(OCC(=O)O)ccc(Sc2ccc(COc3ccc(C(F)(F)F)cc3)cc2OCC#N)c1C +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCCCCCc1ccccc1 +O=S(=O)(c1ccc(-c2cnc(C3CC3)o2)cc1)N1CCCSc2ccccc21 +CCOc1ccc(NC(=O)CCC(=O)n2nc(C)cc2C)cc1 +N=C(N)c1cccc(COc2ccc(C(=N)N)cc2Br)c1 +O=C(NC(CCCCCS)C(=O)NC1CCCC1)OC1CCCCC1 +CCCC(CCCN(CC)CC)Nc1c2ccccc2nc2ccccc12 +N#Cc1cnc(Nc2ccc3c(c2)CC(=O)N3)nc1NCc1ccccn1 +CCOC(=O)N1CCC(N2CCC(n3c(=O)[nH]c4ccccc43)CC2)CC1 +N=C(N)c1ccnc(-c2cccc(-c3cc(C(=N)N)ccn3)c2)c1 +c1ccc2c(c1)CCN(c1cc[n+](Cc3ccc(C[n+]4ccc(N5CCc6ccccc6C5)cc4)cc3)cc1)C2 +CC(C)Cc1cn(-c2ccc(C(=O)O)cc2)cc1C#N +Cn1c(=O)c2c(nc(C=Cc3cccc(NC(=O)CCCCC(=O)O)c3)n2C)n(C)c1=O +CCC(NC(=O)c1c(S(C)(=O)=O)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +CS(=O)(=O)C1(c2nc(-c3cc(F)cc4[nH]ccc34)nc3c2OCC2COCCN32)CC1 +CCN1CCCC1CNC(=O)c1c(O)c(Cl)cc(C)c1OC +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCN1CCCCC1 +CCNC(=O)n1c(=O)n(Cc2nc3ccccc3n2CCC(C)C)c2ccccc21 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(COC3COC3)c12 +CCN(CC)CC(O)CNC1=NC(=NC(=N)Nc2ccc(Cl)c(Cl)c2)N=C(C)C1 +CCC1(c2cccs2)OCC(=O)N(C)c2ccc(-c3ccc(C#N)n3C)cc21 +CC1CCCN(CCC(C)N(C)S(=O)(=O)c2cccc3ccccc23)C1 +Cc1cc(C)c2ncc(NC(=O)Nc3c(F)cc(F)cc3F)c(-c3ccccc3Cl)c2c1 +COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(CCO)CC4)c(OC)cc23)c(Cl)cc1Cl +COC(=O)c1coc(CN2CCC(CNC(=O)c3n[nH]c4ccc(Br)cc34)CC2)n1 +CSc1cnc(-c2ccc(NC(=O)Nc3ccncc3)cc2)nc1N1CCOCC1 +Cc1c(Cn2c(C)nc3c(C(=O)O)cc(N4CCOCC4)nc32)cccc1C(F)(F)F +Nc1cc(C(=O)N2CCSCC2)cc2nc(-c3ccc(Br)o3)nn12 +Cc1nc(NC(=O)c2ccccn2)sc1S(=O)(=O)Cc1ccc(F)cc1F +CC(C)CC(S)C(Cc1ccccc1)C(=O)NC(Cc1ccc(O)cc1)C(=O)O +COCc1nnc(-c2cnc(-c3ccc(C#N)cc3C)cn2)n1-c1ccc(OC)nc1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F)N1CCN(C(=O)N2CCCCC2)CC1 +O=C(c1nc2c(C(F)(F)F)cc(C3CC3)cn2c1Cl)N1CCC2(OCC3(CC3)CO2)C(O)C1 +C=C(COc1ccc(C(F)(F)F)cc1)COc1ccc(OCC(=O)O)c(C)c1 +CC(C)(C)CN1CC(c2nnc(C(=O)c3nc4ccc(-c5ccc(F)cc5)cc4s3)o2)C1 +NC(=O)C12CC3CC(C1)C(OC(=O)N1CCC(Nc4ncccc4C(F)(F)F)C1)C(C3)C2 +Cc1ccc(-c2cnc(Nc3cccc(N4CCNCC4)n3)s2)cn1 +COc1cc(OC)cc(C(=O)N(C)C2CCN(Cc3ccc4ccccc4c3)CC2)c1 +O=C(CCCCOc1ccccc1OCc1ccccc1)C(F)(F)F +CCCn1c(=O)ccc2c(-c3cnc(-c4ccc(C(C)C)nc4)s3)n[nH]c21 +CC(C)(C)c1ccc(C(=O)NCc2ccc(N)cc2Cl)cc1 +c1ccc(-c2ccc(N=c3ccn(CCCN4CCCCC4)c4cc(-c5cnc6ccccc6c5)ccc34)cc2)cc1 +O=C(CC1CCN(S(=O)(=O)Cc2ccccc2)CC1)N1CCC(C2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c32)CC1 +O=C(NCC1CCCCC1)C1Cc2c(sc3ccccc23)CN1 +CCCCN1CCCC1Cn1nc(Cc2ccc(Cl)cc2)c2cccnc2c1=O +Clc1ccc(-c2cncc(N3CC4CC(C3)N4)c2)c(Cl)c1 +COc1ccc(S(=O)(=O)N(Cc2cccc(C)c2[N+](=O)[O-])C(C)C(=O)O)cc1 +CCc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3cc(Cl)ccc32)ccc1OCCN1C(=O)CCC1=O +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCCCCc3ccccc3)ccc21 +Cc1n[nH]c(=O)c(C)c1-c1ccc(Oc2nccc3n[nH]c(C)c23)cc1 +CC(C)c1cccc(C(C)C)c1NS(=O)(=O)CC(=O)N(Cc1ccccc1)C(C)C +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1cccnc1Cl +CC(C)Sc1ccc(CC2CCN(C3CCN(C(=O)c4cccc5ccc(F)cc45)CC3)CC2)cc1 +N#CCCCn1c(Cn2c(=O)n(Cc3ccc(C#N)cc3)c3ccncc32)nc2ccccc21 +CC1(C)CCCN(C(=O)c2cccc(COc3c(Cl)cc(Cl)cc3Cl)n2)C1 +Nc1cccc(Nc2ncnc3c2ncn3CCOc2ccccc2)c1 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+CC(=O)c1ccc2nc(-c3cc(-c4cnn(C5CCNCC5)c4)cnc3N)oc2c1 +O=C1OC(Nc2ncc3nnn(-c4ccccc4)c3n2)c2ccccc21 +COc1ccccc1C(=O)N1CCN(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1 +Nc1ncnc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)c1C=NOC1CCCC1 +COc1cccnc1Cn1ccc2nc(N)nc(NCc3cc(C)on3)c21 +Nc1ccnc(N2CCC(NC3CC3c3ccccc3)CC2)n1 +Cn1c(-c2cn(CCO)nn2)nc(-c2ccc(F)cc2)c1-c1ccncc1 +CCN=C(NC#N)C1=CC(C)(C)Oc2ccc([N+](=O)[O-])cc21 +COc1cc(O)c(-c2c(C)cc(O)c3c(OC)cccc23)c2c1C(C)N(C)C(C)C2 +O=C(NCc1ccccc1)OC(CCl)COc1cccc(C(F)(F)F)c1 +COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2F)CC2CCC1C2 +C[S+]([O-])CCCCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 +COC1Cc2sc(C#N)cc2C2(CCN(Cc3ccccc3)CC2)O1 +COc1cccc(C2C3C(=O)N(c4ccc(C(=O)O)cc4)C(=O)C3ON2c2ccc(C)cc2)c1 +CC1(C)C(C(=O)O)N2C(=O)C(CS)C2S1(=O)=O +CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 +Nc1ccc(C2OC3CC(=O)OC3C3=C2C(=O)c2ccccc2C3=O)cc1 +N#CC(Cc1ccc(-c2cnn(C3CCOCC3)c2)cc1F)NC(=O)C1NC2CCC1C2 +COc1ccccc1NC(=O)c1cn2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc2n1 +CCS(=O)(=O)N(Cc1ccc(F)c(F)c1)c1sc2ccccc2c1C=O +COc1ccc(N=Cc2c(N)ncnc2Nc2ccc3c(cnn3Cc3cccc(F)c3)c2)cc1 +O=C(Nc1ccc(OCc2ccccc2)cc1)C(O)C12CC3CC(CC(C3)C1)C2 +Cc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)NCCCCCCNc1c2c(nc3ccccc13)CCCC2 +COc1cc2[nH]c(=O)c(-c3cccs3)c(-c3cccc(-c4ccccn4)c3)c2cc1OC +COc1ccc(-n2c(C)nnc2SCC(=O)Nc2ccccc2Br)c2ccccc12 +NCCCNCCCCCCCCNC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccncc1 +NC(=O)c1cccc(NCCCN2CCN(c3ccccc3)CC2)c1 +O=[N+]([O-])c1cccnc1N1CCC(=CC#Cc2ccccn2)CC1 +O=C(c1ccc(CCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)ccc12 +Cc1ccc(-c2c(O)nc3cc(Cl)c(NC(=O)NC4CC4)cc3c2OCCC2CCCCN2)cc1C +O=C(c1cc2cc(Cl)ccc2o1)N1CCCC1CN1CCCC1 +CCCC(=O)NC(Cc1ccc(O)cc1)C(=O)NCCCCCNCCCCCCCCCCCCN +COc1ccccc1C=CC(=O)Nc1nc(N)n(-c2ccccc2)n1 +CC#CCOc1ccc(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)c3ccccc3C)CC2)cc1 +Cc1ccc(C(=O)N2CCC(=CC(=O)NC3CCN(Cc4ccc5cc(F)ccc5c4)C3)CC2)c(O)c1 +Cc1nc(N2CCCCC2)c2[nH]c(-c3ccccc3Cl)cc2n1 +O=C(NC(Cc1ccccc1)C(O)CN(OC1CCCC1)S(=O)(=O)c1ccc2c(c1)OCCO2)OC1COC2OCCC12 +CCOC(=O)C(C)(CC(C)C)c1ccnc2c(-c3ccc(Cl)cc3)cnn12 +O=c1[nH]c(N2CCC(c3ccccc3)CC2)c(Cc2ccccc2)c(=O)[nH]1 +O=C(NC1CCCCC1)N1CCN(C(c2ccccc2)c2c(Cl)cccc2Cl)CC1 +CCc1ncc(Cc2cnc3ccccc3c2)c2cc(OC)c(OC)cc12 +NC1=NC2(CCO1)c1cc(NC(=O)c3cnc(O)cn3)ccc1Oc1ncc(Br)cc12 +CCOc1ccc(C2=CS(=O)(=O)CCCS2(=O)=O)cc1 +Cc1c(-c2cccc(O)c2)c(=O)n(CCN(C)CCc2ccccn2)c(=O)n1Cc1c(F)cccc1F +O=C(NCCCCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1)c1ccccc1 +CCN(CC)Cc1ccc(-c2cc(S(=O)(=O)CC)ccc2OC)[nH]1 +O=C(Nc1ccc(-c2nc3cc(NC(=O)C4CCCCC4)ccc3[nH]2)cc1)c1ccc(Cl)c(Cl)c1 +COc1ccccc1N1CCN(CCNS(=O)(=O)c2cccc3c(N(C)C)cccc23)CC1 +Nc1sc(-c2ccc(F)cc2)c(-c2ccc(Cl)cc2)c1C(=O)NC1CC1 +O=C(CCC(=O)N1CCN(CC2CC2)CC1)c1ccc(Cl)cc1 +COc1cccc(CN2CCCC3(CCN(c4cnc5ccccc5n4)CC3)C2=O)c1OC +COc1cc(-c2cc(Cl)cnc2OC)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccnc(C)n3)ccc21 +C[N+](C)([O-])CCNc1ccc2nnn3c4ccccc4c(=O)c1c23 +CCCCC(CC)N(Cc1ccc(C(=O)NCCC(=O)O)cc1)C(=O)Nc1ccc(OC(F)(F)F)cc1 +OCC1NC(COC2OC(CO)C(O)C(O)C2O)C(O)C(O)C1O +Cc1ncc([N+](=O)[O-])n1CCNC(=S)NCc1ccc(S(N)(=O)=O)cc1 +CC(C)(C)CNC(=O)CC(NC(=O)CCc1ccccc1)C(=O)NC(CCc1ccccc1)C(=O)NCC1CC1 +O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1)c1ccncc1 +NC(CC(=O)N1C(C(=O)NC2CC2)CC2CCCCC21)Cc1cc(F)c(F)cc1F +O=C(CC1CC1)N1N=C(c2cccnc2)CC1c1ccccc1O +O=C(O)CC1CCCc2c1[nH]c1ccc(OCc3ccc(C4CCCC4)c(C(F)(F)F)c3)cc21 +N#CC1(n2cc(C(NC(=O)c3ccc(C(N)=O)cc3)C3CCCCC3)nn2)CC1 +O=C(Nc1ccc2c(c1)OCO2)c1cc2cc(C3(O)CCN(CCCc4ccccc4)CC3)ccc2o1 +COCCOc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)cc3)c2cc1NC(=O)C=CCN(C)C +COc1cccc(CNC(=O)c2cn(-c3ccccc3)c3cc(-c4cn[nH]c4)ccc23)c1 +O=C(OC1CCN(c2ccccn2)CC1)N1CCN(C2CCC2)CC1 +O=C1NCCCCC1N(Cc1csnn1)S(=O)(=O)c1ccc(Cl)cc1 +CN(Cc1ccccc1)C(=O)C(Cc1ccccc1)NC(=O)C1CCC(O)CN1C(=O)c1c[nH]c2ccccc12 +CN(C)c1ccc(C=Cc2cc3cc(I)ccc3o2)cc1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NC(C)C(N)=O)[nH]c3ccc(Cl)c(F)c23)c1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1cccc(NC(=O)NCCCN2CCC(C3CCCCC3)CC2)c1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Oc3cccc([N+](=O)[O-])c3)n2)n[nH]1 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+O=C1C(Cl)=C(Nc2ccccc2C(F)(F)F)C(=O)c2c1cccc2[N+](=O)[O-] +CCn1ccc2ccc3c4[nH]c5ccccc5c4c4c(c3c21)C(=O)NC4=O +CCN(CC)CCn1nc2c3c(c(NCCNCCO)ccc31)C(=O)c1ccccc1-2 +CS(=O)(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1F +N#Cc1c(Cc2ccc(S(N)(=O)=O)cc2)c(-c2ccccc2)nn1-c1nc(C(=O)O)cs1 +OC1(c2ccc(Br)cc2)CCN(Cc2cc3ccccc3o2)CC1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2cnco2)s1 +COc1cc(OCc2cccc(OCc3ccccc3F)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CNc1nc(NCCCN(C)C)c2sc(-c3ccc(NS(C)(=O)=O)cc3)cc2n1 +CSc1sc(C(=N)N)cc1-c1csc(Nc2ccc(Cc3ccccc3)cc2)n1 +O=C(Nc1nc2c(s1)CC(N1CCOCC1)CC2)c1cccc(C2CCCN2C(=O)c2ccc(-n3ccnc3)cc2)c1 +Cc1ccc(F)cc1Oc1c(C(=O)N2CCNCC2)c2ccc(O)cc2n1-c1ccc(F)cc1 +COc1ccccc1-n1nnc(C)c1C(=O)N1CCN(c2ccc([N+](=O)[O-])cc2Cl)CC1 +O=C(O)CNC1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +Cc1noc(C)c1-c1ccc(-c2nc3ccccn3c2NC(C)(C)C)cc1 +Cc1cccc(-c2ccc3c(c2)SCc2c-3nc3ccc(F)cc3c2C(=O)O)c1 +CS(=O)(=O)c1ccc(-c2cnc(C#N)n2-c2ccc(F)cc2)cc1 +COc1cc(-c2nc(-c3cc(C)nc(C)c3)c3n2CC(CF)OCC3)ccc1OC(F)F 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+N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1F +Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc(CNCCCCN)cc3)ccc2n1 +O=C(O)c1cncc(-c2ccc(N3CCC(Oc4ccccc4C(F)(F)F)CC3)nn2)c1 +CCCc1cc2c(C(F)(F)F)cc(=O)oc2c(CCC)c1OCCCCN1C(=O)NC(C)(c2ccc(OC)cc2)C1=O +Cc1c(N(CCC2CC2)S(=O)(=O)c2ccc(C(=O)O)cc2)sc2ccccc12 +COc1ccc2c(NC(=O)N3C(C(=O)NCc4cccc(Cl)c4F)CC4CC43)cn(C(N)=O)c2c1 +O=C(c1ccco1)c1cnn2c1n[n+]([O-])c1ccc(-c3ccco3)cc12 +Cc1cc(C(N)=O)ccc1-n1c(CCC(=O)O)ccc1-c1cc(-n2ccnc2)cs1 +Cc1ccc(C(=O)NCc2ccccc2)cc1Nc1nc(NC2CCNC2)nc(N(C)CC(C)(C)C)n1 +O=C(O)c1ccc(Cn2[nH]c(=O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)cc1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCCN(Cc2cccc3c2OCCO3)C1 +CN(C)CCS(=O)(=O)Nc1ccccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 +Cc1cnc(CNC(=O)c2ccc(NC(=O)N3Cc4ccc(F)cc4C3)cc2)o1 +CCOC(=O)N1C2CCC1CC(Oc1ncnc(Oc3cccnc3C)c1C)C2 +CN(CCCOc1ccc2cc(-c3ccc(Cl)cc3)c(=O)oc2c1)Cc1cccc(OC(=O)NCCCCCc2ccccc2)c1 +CCCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cccc(-c3ccccc3)n2)CC1 +CCCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NCc2ccn3nccc3n2)C2CCCC2)nn1 +CC(=O)N1c2cccc(O)c2NC2=C(C(=O)CC(C)(C)C2)C1c1ccc(Oc2ccccc2)cc1Cl +CN1CC(c2cccc(F)c2F)CCC(NC(=O)c2ccc3c(c2)CC2(C3)C(=O)Nc3ncccc32)C1=O +O=C1OCC(C2CCNCC2)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +O=C(NCC1CCOCC1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +O=c1c2ccccc2ccn1CCCCN1CCN(c2cccc3sccc23)CC1 +CCC(NC(=O)c1c([S+](C)[O-])c(-c2ccccc2)nc2cc(Cl)ccc12)c1ccccc1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CCc1cn(C)c3ccccc13)CC2 +CN(c1ccc(OCCCCC(=O)NO)cc1)c1ncnc2ccccc12 +COc1cc2[nH]ncc2cc1Nc1ncnc2[nH]c3c(c12)CC(C(=O)NCc1ccccc1)CC3 +COc1ccc(OC)c(N(C)Cc2cnc3nc(N)nc(N)c3n2)c1 +Cc1cc(C)cc(-c2[nH]c3c(c2C(C)CNCCc2ccncc2)CN(C(=O)C2C(C)(C)C2(C)C)CC3)c1 +Cc1ccc(OCCCOc2c3ccoc3cc3oc(=O)ccc23)cc1 +CCCCNC(=O)CCn1nnnc1C(COCc1ccccc1)NC(=O)C(C)(C)N +CC(C)CC(NC(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)C(=O)O +O=C(Cc1csc(NC(=O)c2ccc3ccccc3n2)n1)NO +COc1ccc2nc(SCC(=O)Nc3ccc(S(N)(=O)=O)cc3)n(Cc3ccccc3)c(=O)c2c1 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+CC(C)(C)C(=O)NC(C(=O)NO)c1ccc(-n2cccn2)cc1 +CCN(C)CC#CCCC1(C2(O)c3ccccc3Sc3ccccc32)SCCCS1 +CC(C)C(C(=O)O)N1C(=O)C2Cc3ccccc3CN2C1(C)C +CC1=CCCC2(C)OC2C(=O)C2CCC(C)C(C)(CC1)C2COc1ccon1 +N=C(N)c1ccc(C#Cc2cc3ccc(C(=N)N)cc3[nH]2)nc1 +CC(C)COc1cccc(CN2CCN(C(=O)Nc3ccccc3)CC2)c1 +CC(C)(C)c1cc(NC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)no1 +CCOc1ccc(C#Cc2ccc(CC(C)NC(=O)C3(C)CC3)cc2)cc1 +O=C(Nc1ccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)cc1)C1CCNC1 +CCN1CCCC1CNC(=O)c1cc2cc(Br)ccc2cc1O +Cc1noc(-c2ccc(Nc3nn(C4CCCCC4C#N)cc3C(N)=O)cc2)n1 +COc1ccc(-c2ccc3[nH]nc(-c4cc(N5CC(C)OC(C)C5)ncn4)c3c2)cn1 +CC(C)c1cccc(CNCC(O)C(Cc2ccccc2)NC(=O)C2CCCC(C(C)(C)N3CCCC3=O)C2)c1 +O=C(NN=Cc1cccc2c1ccn2Cc1ccc(C(F)(F)F)cc1)c1ccc(O)c(Cl)c1 +CC1CCC(C)N1CCc1c[nH]c2ccc(-c3cccs3)cc12 +CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(CCC(c2ccccc2)c2cccc(Cl)c2)CC1 +CC(C)(O)c1ccc(C(CNC(=O)c2cccc(Cl)c2Cl)CC2CC2)cn1 +COc1cc(C(=O)NN2c3ccccc3N=C(N3CCN(C)CC3)c3cc(Cl)ccc32)cc(OC)c1OC +CC(C)(C)NC(=O)C1CCC(n2cc(C(N)=O)c(Nc3ccc(Cl)cc3)n2)C(C#N)C1 +CCc1ncc(C(CNC(=O)c2ccccc2Cl)N2CCC(F)(F)CC2)cn1 +Nc1noc2cccc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 +COc1ccccc1-c1cn(CCC(O)CN2CCN(c3ccccc3OC)CC2)nn1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3cc(C(=O)NC(C)C)[nH]c23)cc1 +O=C(Nc1ccc(F)cc1)c1cnc(N(Cc2ccccc2)Cc2ccc(B(O)O)cn2)nc1 +CCCC(=O)NC(c1ccccc1OC)c1ccc2cccnc2c1O +Cc1nc(C)c(-c2ccnc(Nc3cccc(F)c3)n2)s1 +COc1ccc(C2(c3cc(OC)c(OC)c(OC)c3)CC(C#N)=C(c3ccc(F)cc3)O2)cc1O +Cc1cc(-c2cc(C)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccncn5)ccc43)cc2F)ccc1Cl +O=C(NCc1cccnn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CC(C)Oc1ccc(NC(=O)N2CCN(c3ncnc(N)c3C=NOCC(=O)N3CCOCC3)CC2)cc1 +CCN(CC)CCNCc1cc(C(N)=O)c2ncnc(NCc3cccc(NC(O)c4ccc(OC)cc4)c3)c2c1 +Cc1cc(C)cc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(Br)cc2C)c1 +c1ccc(CN(CCCCN(CC2Cc3ccccc3CN2)C2CCCc3cccnc32)Cc2ccccc2)cc1 +O=c1[nH]c2c(O)ccc(C(O)CNCCSCCCNCCc3cccc(Cl)c3Cl)c2s1 +CCCC1CCC(N2CCC3(CC2)C(=O)NCN3c2ccccc2)CC1 +c1ccc(CNc2sc3ncnc(N4CCC(COCCN5CCCC5)CC4)c3c2-c2ccccc2)cc1 +Cc1c(=O)n(Cc2ccccc2)c(=O)n2cc(C(=O)N3CCC(Oc4ccccc4C(F)(F)F)C3)sc12 +CC(C)(C)C(=O)Oc1ccc(S(=O)(=O)Nc2ccccc2C(=O)OCCO)cc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cc(Br)ccc3O)NC(=O)NC1=O)C2 +Fc1cccc(Cl)c1-c1nc(-c2ccc(CCc3ccccc3)cc2)c[nH]1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NC(C)CC(N)=O)[nH]c3ccc(Cl)c(F)c23)c1 +CCCCNC(=O)NS(=O)(=O)c1ccc(Oc2no[n+]([O-])c2S(=O)(=O)c2ccccc2)cc1 +CCc1nn(C2CC2)c2c1C(c1ccc(Cl)cc1)N(c1cc(C)c3nnc(C)n3c1)C2=O +c1ccc(-c2nnc3sc(-c4ccc5c(c4)OCO5)nn23)nc1 +Clc1ccc(COC(Cn2cccc2)c2ccc(Cl)cc2Cl)cc1 +CCCC1(CC(=O)O)OCCc2c1[nH]c1c(Cl)ccc(Cl)c21 +CN(C(=O)Nc1ccccc1)C1CC(C(=O)O)Nc2cc(Cl)cc(Cl)c21 +FC1(F)CCC(NC(=S)c2cnc(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)n2)CC1 +N#Cc1ncc2nc1OCCCCCOc1cc(OCc3ccccn3)c(Cl)cc1NC(=O)N2 +O=C(Cc1ccc2ccccc2c1)n1sc2ccccc2c1=O +c1cc(CNc2ncnc3ccsc23)cc(Nc2nc3ccccc3[nH]2)c1 +COc1cccc(Cn2c(=O)n(CC3CC3)c(=O)c3c2nc2cc(OC)ccn23)c1 +CCN(CC)CCNC(=O)c1cc(C=C2C(=O)Nc3cc(-c4cccc(O)c4)ccc32)[se]c1C +Nc1nc2ccc(C(=O)c3ccccc3)cc2n1CC1CCNCC1 +CCN(CC)CCCOC(=O)Nc1cccc(CN2N=C(c3ccc(Cl)cc3)CSC2=O)c1 +Nc1cccc(Nc2nc(NCCO)nc(NCCCCNc3nc(NCCO)nc(Nc4cccc(N)c4)n3)n2)c1 +CCN(CC)CC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(C(=O)N2CCCCC2)cc1 +COc1cc(CCc2ccc(C3=Cc4ccccc4C4=NCCN34)cc2)cc(OC)c1OC +O=C1c2c(ccc(O)c2O)CN1Cc1ccc(F)c(Cl)c1 +COc1ccc2c(c1)-c1ncnn1Cc1c(C)ncn1-2 +Cc1cc(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)sn1 +O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1ccc(F)cc1 +CCOC(=O)C(C#N)C(c1ccccc1C(F)(F)F)c1cccc2ccccc12 +CCCNC1CCN(c2ccc(NC(=O)C(C)(C)c3ccccc3)cc2Cl)CC1 +Cn1cc(C2=C(c3cccc(N)c3)C(=O)NC2=O)c2ccccc21 +N#CC1(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc(N)cn3)c(F)c2)CCCC1 +CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc32)ccc1OC(C(=O)O)c1ccccc1 +CCCS(=O)(=O)Nc1cc(F)cc(C(=O)Nc2cnc3[nH]ccc3c2)c1F +O=C(O)c1ccc(Cl)cc1OCCN1CCC(c2cn(Cc3ccoc3)c3ccccc23)CC1 +COc1cc(OCC2CCCCC2)c(F)cc1CNC(=O)C1CCCN1 +O=C1Nc2c(ccc(F)c2F)C1(c1ccc(O)cc1)c1cccs1 +CC(C1CN(C(=O)OC(C)(C)C)CCN1C(=O)Cc1ccc(Cl)c(Cl)c1)N1CCCC1 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+O=C(O)c1cc(-c2cccs2)nc2c1cnn2Cc1ccncc1 +O=c1[nH]cnc2c(CNC(CO)C(O)CO)c[nH]c12 +COc1cc2c(Nc3c(F)ccc(O)c3C)ncnc2cc1OCCN1CCCCC1 +C=CCN(C)CC=CCOc1ccc2c(-c3ccc(Br)cc3)coc2c1 +C(#Cc1ccc2c(c1)OCO2)CON=C1CN2CCC1C2 +CCn1cc(-c2cn3ncc(C(N)=O)c(NC4CN(C(=O)C5(C#N)CC5)CC4CF)c3n2)cn1 +Fc1ccc(-c2ncc(C3CCN(Cc4ccn(-c5ccc(C(F)(F)F)cc5)c4)CC3)[nH]2)cc1 +CCn1ncc(-c2ccncc2)c1-c1ccc(OCc2ccc3ccccc3n2)cc1 +CNC1CCN(c2nc(N)nc3c2sc2cc(Cl)ccc23)C1 +COc1ccc(C(=O)c2cn(C)c3c(OC)c(OC)c(OC)cc23)cc1O +CC(=O)OC1C(C)CC(Oc2c(-c3ccc(O)cc3)oc3cc(O)cc(O)c3c2=O)C(O)C1OC(C)=O +COc1ccc(CO)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +COc1ccc(-c2cccn3nc(Nc4cnn(C(C)CO)c4)nc23)cc1 +O=C(Nc1ccccc1)N1CCN(Cc2cccc(-c3ccccc3)c2)CC1 +COc1ccc(NC(C)=O)cc1-c1nn(C(C)c2ccc(Cl)cc2)c(=O)c2c(C)noc12 +Cc1ccccc1Nc1cc(-c2ccnc(Nc3ccccc3C)c2)ccn1 +COC(=O)c1cccc(-n2cc(-c3nc(-c4ccc(F)cc4)c(-c4ccncc4)n3C)nn2)c1 +CS(=O)(=O)c1ccc2c(c1)C(=O)NC(C(=O)NC1(C#N)CC1)Cc1ccc(c(Cl)c1)OCC=CCO2 +CC1(C)C(=O)C(C#N)=CC2(C)C3=CCCC(O)C3(C)CCC12 +CCC(CS(C)(=O)=O)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(C)OCC2Cc2cccc(-c3ncccn3)c2)c1 +Cc1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1 +CC(O)Cn1cc(-c2cnc(N)c3c(-c4ccc(NC(=O)Nc5cccc(F)c5)cc4)csc23)cn1 +O=C(O)CC(CC1CCN(C(=O)CCc2ccc3c(n2)NCCC3)CC1)c1cccc(F)c1 +CN(C)C1CCN(C(=O)c2ccc(Cn3cnc4ccccc43)cc2)C1 +O=C1C(CC(F)(F)F)=CC(O)(CSc2ncccn2)N1CCNc1ccnc2cc(Cl)ccc12 +CC(C)n1c(=O)n(C(=O)NCN2CCN(C)CC2)c2ccccc21 +CC(NCCc1cccc(Br)c1)c1cccc(COc2nn3c(C(F)(F)F)nnc3c3ccccc23)n1 +C#CCN(C)CC(=C)c1cccc(COc2ccccc2)c1 +O=C(O)C1=C(C(=O)Nc2ccc(-c3cccc(OC(F)(F)F)c3)cc2Cl)CCC1 +Cc1noc(-c2cc(NCCN3CCCC3)c(C)c(N3CCN(c4ncnc5[nH]nc(Br)c45)CC3)c2)n1 +COC1(c2cc(F)cc(OCc3ccc4c(c3)C(C)(C)C(=O)N4C)c2)CCOCC1 +COc1ccc2cc(C(=O)NCCCCCCCNc3c4c(nc5ccccc35)CCCC4)c(=O)oc2c1 +O=C(NC(Cc1ccccc1)C(O)CN(OC1CCCC1)S(=O)(=O)c1ccc(O)cc1)OC1COC2OCCC12 +O=C(NOCc1ccccc1)c1ccc(Sc2ccc([N+](=O)[O-])c3nonc23)cc1 +CCOC(=O)CNc1cccc(Nc2ncc(F)c(Nc3cccc(O)c3)n2)c1 +CN(C)S(=O)(=O)c1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +O=C(O)c1ccccc1NC(=O)N1CC2CC(c3ccccc3C(F)(F)F)CC2C1 +O=C(O)CC1CCC(c2ccc(-c3ccc4nc(C(=O)Nc5ccc(F)cc5C(F)(F)F)cn4c3)cc2)CC1 +COc1cnc2c(C(=O)Nc3cc(Cl)ccc3N3CCC(CO)CC3)cnn2c1 +CC(C)(Cc1cccc(CC(=O)NCc2ccc(O)cc2Cl)c1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1 +CN(C)CCNC(=O)c1cc(NC(=O)CCC(=O)Nc2cc(CO)cc(Nc3c4ccccc4nc4ccccc34)c2)cn1C +Cc1cc(NS(C)(=O)=O)ccc1-c1cnccc1OCC(F)(F)F +CCCNC(=O)c1ccccc1CCC1(O)CCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C +Nc1ccccc1NC(=O)c1ccc(CNc2nccc(-c3ccc(OCCN4CCOCC4)cc3)n2)cc1 +CN(C)C12CCN(CCN)C(C(c3ccc(Cl)cc3)C1)C(c1ccc(Cl)cc1)C2 +CNCC(O)C(c1ccccc1)n1c(=O)n(C2CCC2)c2ccccc21 +COc1ccc(CNc2nccc(-c3c(-c4ccc(F)cc4)ncn3Cc3cccc(C#N)c3)n2)cc1 +CCCCc1ccc(C2=NN(P(=O)(OC)c3ccccc3)CCC2)cc1 +CCC(C)(C)c1ccc(C=CC(=O)Nc2ccc3c(c2)OCCO3)cc1 +COCCn1ccc(-c2nc(C)nc3c2CC(C)N(C(=O)c2cccc(C(F)(F)F)c2Cl)C3)n1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC1(c2ccc(CO)cc2)CCCC1 +COC12CCC3(CC1COCc1ccccc1)C1Cc4ccc(C#N)c5c4C3(CCN1C)C2O5 +O=C(c1ccccc1)c1cc(C(=O)C(F)(F)F)n(-c2cnn(O)c2)c1 +CS(=O)(=O)Nc1cc(Cl)cc(-c2[nH]c(C3CC3)nc2-c2ccnc(N)n2)c1F +CNC(=O)C1OC(n2cnc3c(NCc4cccc(I)c4Cl)ncnc32)C(O)C1O +N=C(NC(=N)N1CCN(C(=N)NC(=N)Nc2ccc(Cl)cc2Cl)CC1)Nc1ccc(Cl)cc1Cl +CCNc1nc2ccc(OC)cc2cc1Cc1c(=O)[nH]c(CNS(C)(=O)=O)c2cc(OC)c(OC)cc12 +CC(c1ccccc1)n1cncc1C(=O)OCc1ccc(C(=O)c2ccccc2)cc1 +COC1COCCC1NC1CCC(C(=O)N2CCN(c3nncc(C(F)(F)F)n3)CC2)(C(C)C)C1 +COc1ccc2c(c1)CCC(NCC1CCC(CNS(=O)(=O)c3ccc4ccccc4c3)CC1)C2Cc1ccccc1 +COC(=O)C1C(OC(c2ccccc2)c2ccc(Cl)cc2)CC2CCC1N2C +CN(Cc1ccc(-c2ccc(Cl)cc2)cc1)C(=O)CCCn1cc(Cc2cnn(C)c2)c(=O)nc1SCc1ccc(F)cc1 +O=C(CCC1=CCN(CCCc2ccc3ccccc3c2)C1=O)NO +Cc1c(CCCl)sc[n+]1CCCCCCCCCCCC[n+]1csc(CCCl)c1C +CN1C(=O)Cc2cc(S(=O)(=O)NNc3ccc(Br)cc3)ccc21 +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1nc(Nc2ccc(N3CCN(C(C)=O)CC3)cc2)ncc1F +Nc1nc2ccccc2c2c1ncn2C1OC(COS(=O)(=O)NC(=O)CCCCC2SCC3NC(=O)NC32)C(O)C1O +Cn1cc(-c2cnc3nnn(Cc4ccc5nccn5n4)c3n2)cn1 +Cc1ccc(C(=O)N2CCC3CCCCC3C2)cc1S(=O)(=O)N1CCC(O)CC1 +Cc1cc(C)c(C=C2C(=O)Nc3ccc(C(=O)NC(CO)c4ccccc4)cc32)[nH]1 +Cc1nc(N2CCCCC2)c2[nH]c(-c3ccccc3)c(-c3ccccc3)c2n1 +COc1cc([S+]([O-])c2ccccc2)cc2c3c(oc12)CCNC3 +CNC(C)C(=O)NC(C(=O)N1c2ncccc2CC1CNC(=O)N(C)C)C(C)C +O=[N+]([O-])C=C1NC=CN1Cc1ccc(Cl)nc1 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC(F)(F)c2ccccc2)C(=O)C(O)CO)c1 +Cc1onc(-c2c(Cl)cccc2Cl)c1NC(=O)OCc1c(F)cccc1Cl +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(C34CCC(CC3)CC4)n2)cc1OC(F)F +CCCCCCOc1c(O)cc(Br)c2c1CN1CCc3cc(OC)c(O)cc3C1C2 +CC(C)CC(NC(=O)C(Cc1cccc2ccccc12)N(C)C(=O)OCc1ccccc1)B(O)O +O=c1[nH]nc(-c2ccnc(NC3CCCCC3)c2)n1-c1ccc2ccccc2c1 +O=C1NC(=O)c2c1c1c3ccc(F)cc3[nH]c1c1c2c2cccc3c2n1CCNC3 +NC1CCN(c2cncc(-c3cc4c(-c5ccccc5F)n[nH]c4cn3)c2)CC1 +CCN1CCCC1CNC(=O)c1c(OC)ccc(S(N)(=O)=O)c1I +CC1(C)C(NC(=O)c2cnccn2)C(C)(C)C1Oc1ccc(C#N)c(Cl)c1 +CCC(C)c1cc2c(C(F)(F)F)cc(=O)[nH]c2cc1N +CCCCN(CC)C1C=C(C(=O)O)CC(N)C1NC(C)=O +CC(C)(CC(O)(Cc1cc2cc(S(C)(=O)=O)ncc2[nH]1)C(F)(F)F)c1ccccc1S(N)(=O)=O +C=C(F)C(=O)Nc1cc(-c2ncnc3[nH]cc(C(=O)OCC)c23)ccc1F 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+CC(C)Cc1cc2c(s1)CNC1CCc3cc(O)c(O)cc3C21 +CCOC(=O)COc1ccc(-c2cc3cc4c(cc3o2)OC(C(C)(C)O)C4)cc1 +O=C(NC(c1ccncc1)c1ccc(Cl)cc1)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1 +O=C(Nc1ccc(CN2CCCC2)cc1)c1sc2ncnc3c2c1[nH]c(=O)n3-c1ccc(F)c(Cl)c1 +O=C(Nc1ccc(CNc2nc(N3CCC3)nc3ccccc23)cc1)c1ccc(F)cc1 +CC1=NC(=S)N(C(=O)OC2CCN(Cc3ccccc3)CC2)C(c2ccccc2[N+](=O)[O-])C1=C(O)OC(C)C +NS(=O)(=O)c1cc(F)ccc1NS(=O)(=O)C=Cc1ccc2ccccc2c1 +CN1C(=N)NC(C)(c2cc(-c3cccc(-c4nnco4)c3)cs2)CS1(=O)=O +COc1cccc(C(=O)N(c2ccccn2)C2CCN(c3cc(N)ccn3)CC2)c1 +CNC(=O)COc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +CC1(c2sc(C(=O)NCc3ccsn3)cc2Cl)CS(=O)(=O)C2(CCCCC2)C(=N)N1 +COc1cc(OC)nc(NCCn2cc(NC(=O)c3ncoc3-c3ccccc3F)cn2)n1 +CCCn1c(=O)c2[nH]c(-c3cnn(Cc4ccccc4)c3)nc2n(CC)c1=O +C=CCN1CC(C)N(C(c2cccc(O)c2)c2cccc(C(=O)N(C)Cc3ccccc3)c2)CC1C +CN(C(=O)NCCC1CCN(CC2COc3ccccc3O2)CC1)c1ccccc1 +C=Cc1cc(Nc2cc(=O)n(CCCCOC)c(=O)[nH]2)ccc1C +CC(C)(C)CCc1ccc(-c2cc3cn(C4CC(O)C(CO)O4)c(=O)nc3o2)cc1 +COc1ccc(C2CN(C)CC2NC(=O)c2ccc3cnc(Nc4cc(C)nn4C)cc3c2)cc1 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+COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(OC(F)(F)F)c(F)c4)cc3)c(=O)c2cc1Cl +CC(C)(C)OC(=O)N1CCC(CN(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Nc1ncccc1-c1noc(CCC2(c3ccccc3)CCCCC2)n1 +O=S(=O)(c1ccccc1)N(Cc1ccc(C(F)(F)F)c(F)c1)c1nc2ccccn2c1Br +CC(C)COc1ccc(-c2cc(C(=O)O)nc(N)n2)cc1C#N +O=C(c1c(Oc2cccc(F)c2F)n(-c2ccccc2)c2cccnc12)N1CCNCC1 +O=c1nc(N2CCOCC2)cc(N(CCO)Cc2cccc3ccccc23)[nH]1 +COc1cc(Nc2nc(N)n(-c3ccccc3)n2)ccc1-c1cnco1 +CCCc1c(OCc2ccc(Oc3ccc(-c4nn[nH]n4)cc3)cc2)ccc2c1ccn2CC(C)(C)C +NC(=O)c1cncc(OCc2cccc(NC(=O)C=Cc3ccccc3)c2)c1 +NC1CCC(NC2CC2c2ccc(-c3cccc(C(F)(F)F)c3)nc2)CC1 +Cc1ccc(NC(=O)N(CCCN2C3CCC2CC(n2c(C)nc4c2CCN(C(=O)C2CCC2)C4)C3)c2ccccc2)cc1 +COc1c(C)c[n+]([O-])c(Cn2cnc3c(Cl)nc(N)nc32)c1C +O=c1oc(N2CCOCC2)nc2sc3c(c12)CCN(Cc1ccccc1)C3 +N#Cc1cc(-c2n[nH]c3ccnc(OC4CCOCC4)c23)ccn1 +N=C(N)c1cccc(N2CCCCN(C3CCN(S(=O)(=O)c4ccccc4N)CC3)C2=O)c1 +COc1ccc2c(c1)CCN1CC3CCCN(S(C)(=O)=O)C3CC21 +O=S(=O)(NCCCCCCCCn1cc(-c2cccnc2)nn1)c1ccccc1Br +FC(F)(F)Oc1ccc(Nc2cc(NCCN3CCOCC3)ncn2)cc1 +COc1ccc(C(C)(NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)Nc2ccc(OC)c(OC)c2)cc1 +O=C(O)c1c(CCCOc2cccc3c2CCCC3)c2cccc3c2n1CCS3 +Cc1ncc(C)c(-c2ccc(N(Cc3ccsc3)C(=O)c3ccc(O)cc3O)cc2)n1 +Clc1ccc(C(c2ccc(Cl)cc2)(c2cncs2)n2ccnc2)cc1 +O=C(NCc1cccnc1)c1cc2n(n1)CCN(Cc1ccc(Cl)c(Cl)c1)C2=O +CC(Oc1nnc(-c2ccn(C)c(=O)c2)n1C)c1cc(-c2cccc(Cl)c2)on1 +CNC(=O)C1CC=C(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +CC1CCC(CC(C(=O)NC(CCCN=C(N)N[N+](=O)[O-])C(=O)Nc2nccs2)C(C(C)C)N(O)C=O)CC1 +O=C(Nc1ccc(OC(F)(F)F)cc1)NC1CCN(C(=O)c2ccncc2)CC1 +O=C(O)c1cnc(C(=O)CCc2ccc(-c3ccccc3)cc2)o1 +Cc1ccccc1-c1nnc(-c2nnn(-c3ccccc3)c2C)o1 +CC1CCC2C(C1)c1cc3c(C(F)(F)F)cc(=O)n(C)c3cc1N2C +CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C(C)(C)O)cc2C)c1C +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccc(C#N)cn23)n1 +Cn1c(N2CCNC(c3ccccc3Cl)C2)nc(-c2ccncn2)cc1=O +COc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1-c1ccnn1C +Cc1ccc2c(c1)c(S(=O)(=O)c1ccccc1Cl)c(C)n2CC(=O)O +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2C2CCCC2)c1 +CCc1ncnc(N2CCC3(CC2)OCCO3)c1C#Cc1ccc(N)nc1 +O=C(O)C(Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccc(O)cc4O)sc4ccccc34)cc2)cc1 +Cc1csc2nc(-c3ccncc3)nc(N3CCCNCC3)c12 +CN(C(=O)OC(C)(C)C)c1ccc(-c2nc3ccccc3s2)cc1 +CC(C)CN(c1ccccc1C(F)(F)F)S(=O)(=O)c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1 +CSc1ccc2c(c1)C(=O)N(CC1(C#Cc3cccnc3)NC(=O)NC1=O)C2 +CC(C)(NC(=O)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1)c1ccccc1 +CNCc1cc(C(=O)N(C)C)ccc1Oc1ccc(Cl)cc1C +CC(C)Nc1cc(-c2[nH]c(SC(C)C)nc2-c2ccc(F)cc2)ccn1 +CCCN(CCC)CCNC(=O)c1cc2c(-c3ccc(Cl)cc3)nn(C)c2s1 +Nc1nccn2c(C3CCC3)nc(-c3ccc(C(=O)c4ccccc4)c(Cl)c3)c12 +CCOC(=O)CC1CC(n2cc(-c3ccccc3)c3c(N)ncnc32)CN1C(=O)OC(C)(C)C +O=C(O)Cc1ccccc1OCCC1Oc2ccccc2N(CCCCCCCF)C1=O +NS(=O)(=O)c1ccc(-n2cc(-c3nc4ccccc4[nH]3)c(-c3ccc(Cl)cc3)n2)cc1 +Cc1ccccc1N1CCN(CC(O)COc2cccc(C(=O)c3ccccc3)c2)CC1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccnc2)CC1 +O=[N+]([O-])c1ccc(CSc2ncnc3c2ncn3Cc2cccc(F)c2)cc1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccncc1 +C=CCC1Oc2cccc(Cl)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +COc1cccc2oc3ccc(C#Cc4ccccn4)cc3c(=O)c12 +CC(C)C(=O)OCC1(CO)CC(=Cc2ccc(F)c(Br)c2)C(=O)O1 +COc1nc(-c2cccnc2)nc2c1CN(C(=O)Nc1ccccc1)CC2 +CC1(C)OC2=C(C(=O)C(=O)c3ccccc32)C1n1cc(CNC2=CC(=O)c3ccccc3C2=O)nn1 +CCCCC(NC(C)=O)C1CC(C(=O)O)CC1NC(=N)N +O=C(c1ccc(F)cc1F)N1CCN(c2ccc(OC3CCN(C4CCC4)CC3)cc2)C(=O)C1 +Cc1c(C(=O)Nc2cccc(C(F)(F)F)c2)cc(-c2ccccc2)n1CCCN(C)C(=O)C(C)C +CN(C)C(=O)CCCCCc1ccc(C(=O)Nc2sc(-c3ccncc3)nc2C(N)=O)cc1 +Cc1nc(NC(=O)NC(C)c2ccccc2)cc2[nH]nc(OCCO)c12 +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)Nc3ccc(F)cc3)sc2c1 +CNC(=O)c1cc(CSc2ncccc2C(=O)Nc2cc(C)cc(C)c2)ccn1 +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)C5CNC(=O)C5)C4)c3C2)cc1C(F)(F)F +CCCCc1nn(CCCOC(=O)N(C)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCCCCN(CC(O)C(Cc1ccccc1)NC(=O)OCCNC(=O)C(F)(F)F)S(=O)(=O)c1ccc2ncsc2c1 +O=C(CCS(=O)(=O)c1ccc2cc(Cl)ccc2c1)N1CCN(c2cccc3nc(CO)cn23)CC1 +CCCCCCCCCCCCOC1(c2ccc(Br)cc2)SC=C(C)n2c1noc2=O +c1ccc(-c2ncc(-c3cnc(-c4ccccn4)[nH]3)cn2)cc1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1ccc(Cl)cc1 +CC(O)C1C(CO)CC2CCCCC2C1C=Cc1ccc(-c2cccc(C(F)(F)F)c2)cn1 +COc1ccc(COc2nc(N3CC4CC4C3)ncc2C(=O)NCc2cnc(C)cn2)cc1Cl +C=C(c1ccccc1)c1ccc2c(C=Cc3ccccc3)n[nH]c2c1 +Cn1cc(-c2cc3c(-c4cc(N5CCCC(F)(F)C5)ncn4)n[nH]c3cc2F)cn1 +CCC(NC(=O)c1cc(C(=O)N2CCC(F)C2)n2c1CCCC2)c1ccccc1 +CC(CCCCn1cnc2c1NC=NCC2O)(C(=O)O)C(=O)OCc1ccccc1 +CCCS(=O)(=O)c1cccc(C#Cc2cc(F)ccc2OCC(=O)O)c1 +C=C(C)c1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +Cn1ccc(Cc2cnc(SCCCCCCCCc3ccccc3)nc2O)cc1=O +COC(=O)C12CC1CCN(C(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)C1=CCCNC1)C(C)C)C2 +CN1CCN(C2Cc3ccccc3Sc3ccc(-c4ccn(C)n4)cc32)CC1 +CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C(=O)N(CCCN(C)C)c3nc4cc(OC)ccc4s3)cc2)CC1 +O=C(O)CC1CCCc2c1n(Cc1cccc(OCCCCCc3cccnc3)c1)c1ccc(F)cc21 +COc1cccc(C#CCN(c2cc(OC)cc(OC)c2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Nc1nc2[nH]c(-c3ccc(Cl)cc3)c(-c3ccc(Cl)cc3)c2c(=O)[nH]1 +CCOC(=O)c1c(NC(=O)Cn2cnc([N+](=O)[O-])n2)sc2c1CCC(C)C2 +NC(=O)c1ccc2c(c1)CCCN2c1cc(F)c(CNC2Cc3ccccc3C2)c(F)c1 +CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1ccc(-c2ccccc2)cc1 +Cn1c(=O)c(Cl)c(Nc2ccc(Br)cc2F)c2c(=O)n(CC(O)CO)cnc21 +O=C(c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1ccc(CN2CCOCC2)cc1)C1CC1 +COc1cccc2c(=O)[nH]c(-c3ccc(Br)cc3)nc12 +COc1cc(N=[N+]=[N-])c(I)cc1C(=O)NC1CCN(Cc2ccccc2)CC1 +O=S(=O)(c1ccc(F)cc1)N(Cc1ccccc1OC1CCOCC1)c1cc(F)ccc1F +Cc1ncoc1-c1nnc(SCCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)n1C +O=C(O)Cc1cc(Br)c(N(Cc2ccc(Oc3ccccc3Br)cc2)Cc2cc(F)cc(F)c2)c(Br)c1 +Cc1ccccc1OCC(=O)NN=Cc1ccc([N+](=O)[O-])o1 +COc1n[nH]c2ncc(NC(=O)c3c(F)ccc(NS(=O)(=O)Cc4ccccc4)c3F)cc12 +CCCCCNC(=O)NCCCCC=CCCCCCCC(=O)NS(=O)(=O)c1ccccc1 +CC12CCC3C(CCC4CCOCCC43C)C1CC=C2c1cccnc1 +O=C(c1csc(-c2cccc(Cl)c2Cl)n1)N1CCCOCC1 +Cc1ccc(C(=O)NCC(N)=O)cc1-c1nnc2ccc(Sc3ccc(F)cc3F)cn12 +CC(C)Oc1ccc2c(c1)C(c1ccc(F)cc1)=C(C(=O)O)C(c1ccc3c(c1)OCO3)O2 +CCc1nn(Cc2ccc(S(=O)(=O)Nc3ccc(C)c(Cl)c3)cc2)c(CC)c1CC(=O)O +CC(C(=O)Nc1ccc(C(=O)O)cc1)n1ccc(-c2cc(Cl)ccc2Cl)cc1=O +COc1cc(CCN2CCN(CCCc3ccccc3)CC2)ccc1OCCF +CN(C)C(=O)CN1CCc2ccc(Nc3nc4c(-c5cccc6c5OC(F)(F)O6)cccn4n3)cc2CC1 +NC1=NC(c2cccc(NC(=O)c3ccc(Cl)cn3)c2)(C(F)F)COC1 +COc1ccc(N2C(=O)Nc3cc(OC)c(OC)cc3C2c2ccc(Cl)cc2)cc1 +O=C(Nc1ccccc1-c1ccc(Cl)cc1)c1cccnc1Cl +Cc1ccc(-c2nc(N)c3cc(Cc4ccccc4Cl)sc3n2)o1 +CC(C)=C1CC(C)(c2cc(NC(=O)c3cnc(C)cn3)ccc2F)N=C(N)S1 +COc1ccc(N(C(=O)c2ccco2)C(C(=O)NC2CCCC2)c2ccccc2F)c(OC)c1 +Cc1nccc(-c2ccc(Cl)c(C(=O)N(C)CCCN(C)C)c2)c1C#Cc1ccc(N)nc1 +CN(C)CCCC1(c2ccc(F)cc2)OCc2cc(C=Cc3ccc(C#N)cc3)ccc21 +COc1cc(C(=O)c2sc(-c3ccccc3Cl)cc2N)cc(OC)c1OC +COc1ccc(N=Nc2sc(N3Nc4onc(-c5ccccc5)c4C3c3ccc(Cl)cc3)nc2C)cc1 +O=C(O)CCc1ccccc1CCC1C2CCC(O2)C1c1nc(C(=O)NCCCCC2CCCCC2)co1 +CN(c1cc(CCC2CC2)cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CC2)c1)S(C)(=O)=O +CCn1nnc(C2OC(n3cnc4c(Nc5ccc(Cl)cc5F)nc(Cl)nc43)C(O)C2O)n1 +CN(C)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +CC(C(=O)NC1CC(=O)OC1O)N1CCCCC(NC(=O)OCc2ccccc2)C1=O +COc1cccc(N2CCN(CCCCOc3ccc4c(C)cc(=O)oc4c3)CC2)c1 +CCCCCCCCCCCCCC(=O)OC1CCC(NC(=O)C(OC)C(O)C(O)C(O)C=CC(C)C)C(=O)N(C)C1 +CN(C)Cc1nc2c(sc3ccc(C#CCCCCN4CCCCC4)cc32)c(=O)[nH]1 +CCCCCCCCCCCCCCCCNC(=O)C(N)COP(=O)(O)O +O=c1ccc2ncc(F)c3c2n1CC3(O)CC12CCC(NCC=Cc3ccccc3)(CC1)CO2 +CCCCCCCCN(C)C(S)=NCc1ccc(O)c(OC)c1 +O=C(c1ccc(F)cc1C(F)(F)F)N(c1ccc(O)cc1)c1ccc(OCCN2CCCCC2)cc1 +CN(c1ncc(F)cn1)C1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 +COC(C)COc1cc(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)ccn1 +Cc1nc(O)c2c(Sc3ccc(S(=O)(=O)c4ccccc4)cc3)c(C)ccc2n1 +O=C(NCc1ccncc1)c1cc(F)cc(C(F)(F)F)c1 +O=C(NO)C1CC2(CN1S(=O)(=O)c1ccccc1)OCCO2 +CCCCc1nc2cc(S(=O)(=O)NC(C)C)ccc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(Nc1cccc(O)c1)c1ccc(OCCCN2CCCC2)cc1OCc1cscn1 +CN1CCCCC1C(=O)N1CCC(n2cnc3cnc4[nH]ccc4c32)CC1 +C(=Cc1ccccc1)CN1CCN(CC2ON=C3c4ccccc4NCC32)CC1 +CCCCCc1ccc(S(=O)(=O)NCCc2c[nH]c3ccccc23)cc1 +O=c1[nH]c(N2CCC(N3CC=C(c4ccccc4)CC3)C2)nc2ccccc12 +Clc1ccccc1-c1csc2nc(N3C4CCC3COC4)nc(N3C4CCC3COC4)c12 +CCC(=O)n1c2ccccc2c2cc(CN3CCC4(C=Cc5ccccc54)CC3)ccc21 +Cc1cc(-c2c(O)nc3cc(Cl)c(C(=O)Nc4cnsn4)cc3c2OCCC2CCO2)cc(C)c1C +Clc1ccc2c(NCCCCCCCNc3c4c(nc5cc(Cl)ccc35)CCCC4)c3c(nc2c1)CCCC3 +COc1cc(CNC(=O)c2cc(-c3ccc(C(C)(C)C)cc3)n(C)n2)ccc1OC(C)(C)C(=O)O 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+Cc1cc(CC(NC(=O)N2CCC(c3cccc(Br)c3)CC2)C(=O)N2CCC(N3CCCCC3)CC2)cc2cn[nH]c12 +N#Cc1cc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)oc3c2)ccc1F +COc1cc(-c2ccc(NC(C)c3ccc(F)cc3)nc2)ccc1-c1cc(C)ns1 +Oc1cccc(-c2cc(Nc3cnc4ccccc4c3)nc(N3CCOCC3)n2)c1 +Cn1c(=O)[nH]c2cc(-c3nn(C(C)(C)C)c(N)c3C(N)=O)ccc21 +Cc1ccc2c(C#N)c(-c3ccc(S(=O)(=O)NC(C)C(F)(F)F)cn3)n(-c3ncccn3)c2c1 +OCC1OC(n2cnc3c(NCc4cccnc4)ncnc32)C(O)C1O +COc1ccccc1NC(=O)N1CCC(c2nc(-c3cc4ccccc4cn3)no2)CC1 +CC(NC(=O)c1ccc(-c2nc(C3=CCCCC3)cnc2N)cc1F)c1cc(F)cc(S(C)(=O)=O)c1 +O=C(O)C=NOC(c1ccc(OCc2ccccn2)cc1)C1CCCCC1 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3c(F)c(F)c(F)cc3[nH]2)o1 +COC(=O)C(C)CN(c1ccc2c(c1)nc(C)n2Cc1ccc2ccc(C(=N)N)cc2c1)C1CCN(C(C)=N)CC1 +C=CCN(CC#N)C(=O)C(N)C12CC3CC(CC(C3)C1)C2 +CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C#N)cccc32)c1 +CN(C)Cc1c(C(=O)NCCCCN2CCN(c3cc(C(F)(F)F)nc(C(C)(C)C)n3)CC2)[nH]c2ccccc12 +CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1cc(F)cc(Cl)c1 +O=C(O)c1cc(-c2ccc(Br)cc2)nc2ccc(OC(F)(F)F)cc12 +COc1ccc(C2CN(C)Cc3cc(OCCCNC4CC4)ccc32)cc1 +Cc1cc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)cc(C2CCCC2)n1 +O=C(NC1CCc2ccccc21)c1cncc(N2CC3CNCC3C2)c1 +CC1(C)OB(c2ccc(C(=O)Nc3nnc(S(N)(=O)=O)s3)cc2)OC1(C)C +COc1cc(C(=O)c2n[nH]c3c(C#CCO)c(OC)ccc23)cc(OC)c1OC +Cc1nc2cc(Cl)c(-c3ccc(C(=O)Nc4ccccc4F)s3)cc2o1 +COc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc(Cl)cc2)ccc1CCCN1C(=O)CCC1=O +O=C(NCC(C(=O)O)S(=O)(=O)c1c(Cl)cccc1Cl)C1=NOC2(CCC(CNc3ncc[nH]3)CC2)C1 +c1ccc(CN2CCN(c3cccc4ccoc34)CC2)cc1 +CCC=CCC=CCC=CCCCCCCCC(=O)OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(O)c(O)c1 +Cn1c2c(c3ccccc31)CN(CCCOc1ccc3ccccc3c1)CC2 +COc1ccc(-c2nc3cc(-c4csc(C(=O)NCCC(C)C)c4)cnc3[nH]2)cc1 +Cn1cncc1CN1CC(N(Cc2ccsc2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21 +CCCOc1cccc(-c2ccc(CCCC(P(=O)(O)O)S(=O)(=O)O)cc2)c1 +O=C(NCCCCc1ccccc1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 +O=C(Nc1ccc(C2CCCCC2)cc1)c1nnc(Nc2ccccc2F)o1 +NS(=O)(=O)OCC1OC(n2cnc3c(CN4Cc5ccccc5C4)ncnc32)C(O)C1O +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)C5CCOCC5)C4)c3C2)cc1Cl +COc1cccc(C(=O)NC(c2ccccc2OC)c2cc(Cl)c3cccnc3c2O)c1 +Cc1nc(N2CCN(C(=O)C3CCC3)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +O=C(CN1CCC(O)CC1)C(O)(c1ccccc1)C1CCC1 +O=C(NCCCCN1CCN(c2nsc3ccccc23)CC1)c1[nH]nc2ccccc12 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1C#CC(C)(C)NS(C)(=O)=O +CCc1cc(F)c(Cc2cnc(Nc3ccc(Oc4cccnc4)c(Cl)c3)o2)c(F)c1 +Cc1ccc(Cc2ccc3c(c2)CC(=O)N(O)C3=O)cc1 +Cc1ccc(Cn2nc(C(=O)NN3CCCCC3)c3c2-c2c(C)csc2C3)cc1 +Cc1cn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-n3cnc(-c4ccccc4)c3)c12 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccc(OC(F)(F)F)cc4)nc23)N1 +COc1cc(C)cc2cc(-c3c(COCCO)c(CN4CCNC(=O)C4)n4ncnc(N)c34)sc12 +Cc1c(C=C2C(=O)NN=C2c2cnccn2)[nH]c2ccccc12 +O=c1ccn(COCCCS(=O)(=O)NCc2cccc(OCC3CC3)c2)c(=O)[nH]1 +CC(C)(CO)NCc1noc(C(CCCC2CCCCC2)CC(=O)NO)n1 +CCNC(=O)c1ccc(-c2cc3nnn(C4CCN(c5ncc(CC)cn5)CC4)c3cn2)cc1Cl +Cn1cc(C=C2Oc3cc(O)cc(O)c3C2=O)c2c(-c3ccccc3)ccnc21 +Cc1cccc2cc(C(C)Nc3nc(F)nc4[nH]cnc34)n(-c3ccccc3)c(=O)c12 +N#Cc1c2n(c3c(N4CCN(CCc5cccc([N+](=O)[O-])c5)CC4)ncnc13)CCCC2 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(C3CCOCOC3)c2)CCCCC1 +CCCN(CCc1ccccc1)C(=O)C1OC(C(O)O)=CC(N)C1NC(C)=O +CC(C)(C)C#Cc1cnc2c(c1)C1(COC(N)=N1)c1cc(-c3cccnc3F)ccc1O2 +O=C1NCc2nc(Sc3ccc(F)cc3)ccc2N1c1c(F)cccc1Cl +O=C(O)c1cc2cc(OCc3c(Cl)cccc3Cl)ccc2n1Cc1cc2c(cc1Cl)OCO2 +C[S+]([O-])c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1 +COCCOCCOCCOCCOCCOCCOCCOCCOC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CCC2)C1O5 +CCCCCN(CCCCC)c1nc2nn(C)cc2c2nc(-c3ccco3)nn12 +CCCn1c(=O)c2[nH]c(-c3cc(C)n(CC(=O)Nc4ccc(Cl)cc4)n3)nc2n(CCC)c1=O +Cc1ncccc1NC(=NC#N)NC(NC(=O)CCCCc1ccccc1)C(C)(C)C +CCN(CC)CCNC(=O)C1c2ccc(OCc3ccccc3)cc2CCN1C(=O)OC(C)(C)C +CC(C)(C)CN(C(=O)CCC(=O)N1CCC(C(=O)O)CC1)c1ccc(Cl)cc1C(O)c1cccc(F)c1Cl +COc1cc(C=Cc2nc(-c3ccccc3)c[nH]2)ccc1-n1cnc(C)c1 +CCN(C)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3C)cc1 +Nc1ncc(F)n2c(C3CCC4CCC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3)c12 +COc1cc2c(Oc3ccc(NC(=O)c4cn(-c5ccccc5Cl)nn4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 +Cc1ccc(C2CC3CCC(C2c2nnc(-c4ccccc4)s2)N3C)cc1 +O=C1OC2(CCC(O)CC2)CCN1C(c1ccc(Br)cc1)C1CC1 +N#Cc1nccc(N2CCC(S(=O)(=O)c3ccccc3C(F)(F)F)C2)n1 +CN(C)CCNC(=O)c1c(C(N)=O)nc2n1CCOc1cc(F)c(C#CC(C)(C)O)cc1-2 +N#Cc1cnc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)cc1OCC1CCCO1 +COc1cc(C=Cc2csc3ccccc23)cc(OC)c1OC +CC(C)CC(O)C(O)C(CC1CCCCC1)NC(=O)C(C)OC(Cc1ccccc1)C(=O)N1CCCCC1 +CC(C)CN(Cc1ccc(N2CCC(S(C)(=O)=O)C2)cc1)S(=O)(=O)Cc1ccccc1 +OC1(c2ccc(Cl)cc2)CCN(Cc2coc3ccccc23)CC1 +CCCN(CCC)C1CCn2c(C=C(C#N)C#N)ccc2C1 +Fc1ccccc1-c1ccc2oc(N3CCN4CCC3CC4)nc2n1 +CCCc1nc(C(=O)NCCN2CCN(c3cccc(Cl)c3Cl)CC2)cn1-c1ccc(Cl)cc1 +CCc1cc(Cc2cnc(N)nc2N)cc2c1NC(C)(C)C=C2C +CCNc1ccc(C#Cc2c(CC)ncnc2-c2ccc(C(=O)N3CCC4(CC3)COC4)c(F)c2)cn1 +N#CC(NC(Cc1ccccc1)C(N)=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc1ccccc1 +Nc1nccn2c(C3CCC4CCC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)on4)cc3)c12 +COC(=O)C(NC(=O)c1ccc(Sc2c(C)ccc3nc(N)nc(O)c23)cc1)c1cccc(O)c1 +FC(F)(F)c1ccc2nc(C3CCN(Cc4ccc(-c5nc6ccnn6cc5-c5ccccc5)cc4)CC3)[nH]c2c1 +CN(C)c1nc(NCCCNCCCCCCCCCCCCNCCCNc2nc(N(C)C)nc(N(C)C)n2)nc(N(C)C)n1 +O=C1Cc2ccccc2C2(CCN(C(=O)Nc3cnc(-c4ccccc4)cn3)CC2)N1 +COc1cc(F)ccc1-c1nc(Nc2cc(Cl)cc(CS(C)(=N)=O)c2)ncc1F +Nc1ccc(-c2nc3ccc(-c4nc5ccc(F)cc5s4)cc3s2)cc1 +Cc1cc(C2CCCN2c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)on1 +CCc1c(Cl)nc(NCc2ccc3c(n2)NCCC3)c(=O)n1CC(=O)NC(CC(=O)O)c1cccc(F)c1 +CC(C)C(O)(c1ccc(C#N)c(Cl)c1Cl)C(F)(F)F +O=c1cc(N2CC3CC2CO3)nc2n1CCC(C(F)(F)F)N2CC1CCOCC1 +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2cccc(F)c2)c(C)c1 +COc1ccc(NC(=O)NCc2cnc3scc(-c4ccc(Br)cc4)n23)cc1 +CCCCCCc1nc2cc(C=CC(=O)NO)ccc2n1C1CCNC1 +O=c1[nH]nc(Cc2c(Cl)cccc2Cl)c2ccccc12 +COc1ccc2c(c1)C(=O)C(=Cc1ccc(CN(C)Cc3ccccc3)cc1)C2 +CN(C)C(=O)Oc1ccc(CC(Nc2ncncc2-c2ccncc2)C(=O)O)cc1 +CC(C)c1cccn2c(C3(c4ccc(Cl)cc4)CC3)nnc12 +COC(=O)C=Cc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1 +COc1cccc2c(C(=O)c3cccc4ccccc34)c(C)n(CCN3CCOCC3)c12 +COc1ccccc1C=c1c(=O)[nH]c(=Cc2cccc(Cl)c2Cl)c(=O)n1C +CC1(C)C(=O)C(c2ccc(S(C)(=O)=O)cc2)=C1c1ccccc1 +Nc1ccc(Cl)c[n+]1CCCCCCCCCCCC[n+]1cc(Cl)ccc1N +CCCN(c1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2C)ncn1)C1CCCCC1 +N#Cc1cccc(C(=O)NCCc2nc(-c3cccc(F)c3)cs2)c1 +COc1n[nH]c2ncc(NC(=O)c3cc(NC(=O)c4cccc(C(C)(C)C#N)c4)ccc3C)cc12 +COc1cc2c(-c3cc(OCC4CC4)cc(OCC4CC4)c3)nc(OCCCO)nc2cc1OCCO +CCCCC1NC(=O)CN(C)C(=O)C(CCC)NCCOc2ccccc2CCCNC1=O +Cc1ccc2c3c(ccc2n1)OCC(CN1CCN(c2ccc4ccccc4n2)CC1)O3 +CCCCC1(O)CCN(C(c2ccccc2)c2ccccc2)CC1 +Cc1cccc(C(=O)N2CCc3nc(C#Cc4ccccc4)sc3C2)c1 +C#CCCCn1ncc2c(N)c(C(=O)OCC3CC3)c(C)nc21 +CC(OC(=O)Nc1cnoc1-c1ccc(CSCC(=O)O)cc1)c1ccccc1Cl +COc1ccccc1Sc1ccc(-c2ccnc(N3CCC(CO)CC3)c2)cc1C(F)(F)F +NS(=O)(=O)c1ccccc1NS(=O)(=O)CCc1ccc(OC(F)(F)C(F)F)cc1 +CC1(C)CN(C(=O)c2ccc(Nc3nc(C4CC4)cn4c(-c5cn[nH]c5)cnc34)c(F)c2)CCN1 +O=C(Nc1ccc(Nc2ccc([N+](=O)[O-])c3ncnc(O)c23)cc1)Nc1ccc(C(F)(F)F)cc1Cl +COc1cc(Nc2ncnc(N3CCCc4cc(C)ccc43)n2)cc(OC)c1OC +Nc1c(N=Nc2ccc(-c3ccccc3OCCC[Na])nc2)cc(S(=O)(=O)O[Na])c2ccccc12 +COc1ccc2sc(C3CCN(CC(O)COc4cccc5[nH]ccc45)C(C)C3)cc2c1OC +Cc1cc(Cl)nc(C)c1C(=O)NCCC(C)N1CCC(N(Cc2ccsc2)C(=O)N(C)C)CC1 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+O=[N+]([O-])OCCNCCNc1c2c(nc3ccccc13)CCCC2 +COc1ccc(CCNCCCNC(=O)c2ccc([N+](=O)[O-])cc2)cc1OC +Cc1cccc(C)c1Nc1cccc(C(=O)NCCCCCCC(=O)NO)c1 +O=C(O)CCc1cccc(CC(=O)Nc2cc(-c3ccc(Cl)cc3)n[nH]2)c1 +OCC1OC(n2cnc3c(NCC4=CCCCc5ccccc54)ncnc32)C(O)C1O +COc1cc(-c2noc(NC(C)c3ccc(F)cc3)n2)ccc1-n1cnc(C)c1 +COC(=O)NC(=O)C1CCCN1C(=O)C(CC1CCCC1)CN(O)C=O +O=C(NCCCc1ccccc1)Nc1cccc(CCNCC(O)c2ccc(O)c3[nH]c(=O)ccc23)c1 +Cc1cc2c(OCC(O)CN3CCC(c4cc5c(C)cccc5s4)CC3C)cccc2[nH]1 +Cc1ccc(C(=O)N2CC(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C(C)(F)F)nc1C +O=C(Cc1ccccc1)N1Cc2c(nc3ccccc3c2O)C1c1ccc2c(c1)OCO2 +N#Cc1ccc(C2NC(=O)N(c3cccc(C(F)F)c3)C3=C2C(=O)CC3)cc1 +O=C(NCC1CCCNC1)c1ccnc2nc(Cc3cccs3)[nH]c12 +CC(=O)c1cccc(C#CC2(O)CCC3(C)C(CCC4C3CCC3(C)C(C(C)=O)CCC43)C2)c1 +CCCCNS(=O)(=O)n1nc(C(N)=O)c2c1-c1c[nH]nc1CC2 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCCCc1cn(CCCO)nn1 +CNC(=O)c1cccc(-c2n[nH]c3ccnc(OC4CCOCC4)c23)c1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(CCc1ccccc1)C(=O)COc1ccccc1 +Cn1nnc(-c2ccc3c(c2)c(C2CCN(CCN4CCNC4=O)CC2)cn3-c2ccc(F)cc2)n1 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+O=C(Cc1ccccc1)NC1CC(C(=O)O)Nc2cc(I)cc(Cl)c21 +O=C(COC(=O)c1ccccc1Br)Nc1nnc(-c2ccccc2)o1 +O=C(O)COCC1CCC(COC(=O)N(c2ccc(F)cc2)c2ccc(Cl)cc2)CC1 +COc1ccc(F)c(CCNC(=S)Nc2ccc(Br)cn2)c1F +O=C(CCCCCCOc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1)NO +Cc1nc(-c2nc[nH]n2)ccc1-c1cnc2c(n1)N(CCC1CCOCC1)C(=O)CN2 +CC(CCn1cc(-c2ccc(Cl)cc2F)nn1)(C(=O)NO)S(C)(=O)=O +CN1C2CCC1CC(OC(=O)N(Cc1ccccc1)c1ccsc1)C2 +O=C(c1ccoc1)N(c1ncccn1)C1CCN(CCc2ccccc2)CC1 +CCCCN(CCCC)CCCNc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2CCCCO +O=C(Cc1cn2cc(Cl)ccc2n1)N1CCC2(CC1)CN(Cc1ccc(-c3ncccn3)cc1)C2 +COC(=O)Nc1nc2cc([Se]c3c[nH]c4ccc(C#N)cc34)ccc2[nH]1 +O=C1C(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1c1ccc2c(c1)CCNC2 +CCSC(=S)SCC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 +CCNC(=O)Nc1nc2nc(NCCCN3CCN(C)CC3)ncc2cc1-c1c(Cl)cccc1Cl +COc1ccc(S(=O)(=O)Oc2c3ccccc3cc3ccccc23)cc1 +CC(C)c1ccc2occ(C=C3SC(=O)N(CC(=O)O)C3=O)c(=O)c2c1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C)cn2)nc(N2CCOCC2)nc1OCCOC(=O)Nc1ccccn1 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+COc1cc2c(cc1OCCCN1CCCCC1)Cc1c-2n[nH]c1-c1ccc(-c2ccc(O)cc2)cc1 +Cc1cn(C2COC(COC(=O)C(N)CCC(=O)O)O2)c(=O)[nH]c1=O +N=C(N)NCCCC1C(=O)N(C(=O)c2ccc(-c3ccccc3)cc2)C1C(=O)O +COc1cc(N2CCN(C3CCOCC3)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1Cc1cccc(Cl)c1)CC2 +O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)s1 +COc1ccc2ccc(=O)oc2c1C1=NN(S(=O)(=O)c2ccc(Cl)cc2)C(c2cccs2)C1 +CC(Cc1ccccc1)Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O +CC1CCC(Cn2c(N3C(C)CCC3C)nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +COc1cc(C(=O)C2COC(c3ccccc3)=N2)cc(OC)c1OC +CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1ccc2[nH]ccc2c1 +CC#CCOc1ccc(S(=O)(=O)N2Cc3ccc(CN4CCNCC4)cc3N(C(C)=O)CC2C(=O)NO)cc1 +CC(C)(NS(=O)(=O)c1cccc(OCC2CC2)c1)c1ccc(Cn2ccc(=O)[nH]c2=O)cc1 +CNc1nc(Nc2c(C)cc(C)cc2C)nc(NC2CCN(Cc3ccc(S(N)(=O)=O)cc3)CC2)n1 +O=C(Nc1ccon1)NC12CC3CC(CC(C3)C1)C2 +O=C(NCC(F)(F)F)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 +CCc1cc2cc(C(=O)C3CCC(OC)CC3)ccc2nc1F +CC(c1ccc(F)cn1)c1c(CCN(C)C)sc2ccccc12 +Nc1c2c(nc3c1C(c1ccccc1)c1c(c4ccccc4oc1=O)O3)CCCC2 +O=C(CSc1nc2ccccc2c(=O)[nH]1)NC1CCC(c2nnc(-c3ccccc3)o2)CC1 +Oc1ccc(CC(O)CN2CCC(O)(Cc3ccccc3)CC2)cc1 +CCCCCCCCc1ccc(-c2cc3cn(C4CC(O)C(CO)O4)c(=O)nc3o2)cc1 +O=C(NCc1cccc(Br)c1F)C1CC(F)CN1C(=O)Cn1cc(C(=O)C(F)(F)F)c2ccccc21 +CCOc1cc(C=NNC(=O)C(OC)c2ccc3c(c2)OCCO3)cc(Br)c1OC +NS(=O)(=O)c1ccc(NC(=O)CSC(=O)N2CCCc3cccc(Cl)c32)c(Cl)c1 +O=C(COC(=O)Cn1cnc2ccccc21)Nc1cc2c(cc1Cl)C(=O)c1ccccc1C2=O +C=CC(=O)N1CCC(Oc2cc3c(Nc4ccc(Br)c(Cl)c4F)ncnc3cc2OC)C1 +COc1ccccc1CNC(=O)N1CCc2ncsc2C1c1cc(Cl)ccc1OCC(=O)O +O=c1[nH]ccc2c(Nc3c(Cl)cc(-c4ccn[nH]4)cc3Cl)nc3ccncc3c12 +COCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCC(N)=O)C(C)C)ccc1OC +CC(CCc1ccc(-c2ccc(C#N)cc2)cc1)(C(=O)NO)S(C)(=O)=O +CC(C)(C)NC(=O)NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Oc1ccc(I)cc1 +C=CCN1CC(C)N(C(c2ccccc2)c2ccccc2)CC1C +CNC(=O)c1cc2cc(OC)c(OC)cc2c2cnc3cc4c(cc3c12)OCO4 +N=C(N)c1ccc2[nH]c(Cc3nc4c(F)cc(F)cc4[nH]3)nc2c1 +O=C1OCc2cc(CCN3CCN(C(=O)Cc4ccc(-n5cnnn5)cc4)CC3)cc(F)c21 +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc(C#CCOC)cc2)cc1 +O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CN(C2CCC(C3CCCCO3)CC2)C1 +CN1CCN(C(=O)Cn2cc(C(=O)N3CCC4(CC3)OCc3ccccc34)c3ccc(Cl)cc32)CC1 +O=C(Nc1ccc(CC(NS(=O)(=O)c2ccccc2)C(=O)O)cc1)c1cccc(NC2=NCCCN2)c1 +Cc1c(Cl)cccc1C(=O)N1CCCC(n2nnc(-c3ccccc3)n2)C1 +N#Cc1cnc(N)nc1N1CCCC1c1nc2cccc(C(F)(F)F)c2c(=O)n1-c1ccccc1 +Cn1cccc1Cc1ncc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)n1 +CCCCCCCOc1ccc(OC)c(Cc2cnc(N)nc2N)c1 +CN1C2CCC1C(C(O)C(F)(F)F)C(c1ccc(Cl)cc1)C2 +O=C(CNc1ncnc2ccc(C(F)(F)F)cc12)NC1CN(C2CCC(c3ccccc3O)CC2)C1 +COc1ccc(-c2nnnn2-c2cc(OC)c(OC)c(OC)c2)cc1Cl +CCOC(=O)c1cc(-c2cccc(OC(=O)NC3CCCCC3)c2)n(Cc2ccccc2)n1 +CC(C)CNCc1cccc(C(=O)c2csc(S(N)(=O)=O)c2)c1 +N#Cc1ccc(NC(=S)NC(=N)Cc2ccc(Cl)cc2Cl)cc1 +COc1ccc(Nc2nc(Nc3ccccc3)nc(N3CCOCC3)n2)cc1 +CCNC(=O)Nc1ccc(-c2cc3ccc(OC(=O)N(CC)CC)cc3oc2=O)cc1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1CC=CCC1C(=O)O +Cc1cc(O)cc(C)c1CC(N)C(=O)NC(CCCNC(=N)N)C(=O)NC1Cc2ccccc2CN(CCC(N)=O)C1=O +CCn1c(NC(C)C)nc2c(C3CCNCC3)csc2c1=O +Clc1cccc(-c2cc(NCc3ccncc3)n3nccc3n2)c1Cl +CCCCC1N(CC2CCCCC2)C(=O)OC12CCN(C1CCN(C(=O)c3c(C)cccc3C)CC1)CC2 +CCCCCCCCCCCCCCCCCCOCCOP1(=O)COC(Cn2ccc(N)nc2=O)CO1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(-c2nnc[nH]2)cc1 +N#CC(Cc1ccc(-c2ccc3c(c2)CC(=O)N3)cc1F)NC(=O)C1NC2CCC1C2 +CCCNC(=O)CCC(=O)Nc1ccc2c(c1)C(=O)C(=O)NC2=O +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1ccc(OCc2ccncc2)cc1 +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)c5cncn5C)C4)c3C2)cc1C(F)(F)F +COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4nc(C)no4)cc3)C2C2CCCCC2)cc1 +Cn1cc(S(C)(=O)=O)nc1-c1c2c(=O)n(C)c(=O)n(CC3CC3)c2nn1Cc1ccnc2ccc(Cl)cc12 +CCCN(C)C1CCN(C(=O)c2ccc(Nc3nccc(-c4cnc(C)n4C(C)C)n3)cc2)C1 +COc1ccccc1N1CCN(CC(O)c2ccc(O)c(C(N)=O)c2)CC1 +COc1ccccc1N1CCN(CCCCn2cc(-c3ccc(Br)cc3)nn2)CC1 +O=C(Nc1ccc(Cl)c(S(=O)(=O)CC2CCNC2)c1O)Nc1cccc(F)c1Cl +COc1cccc(-c2cc3cnc(N)nc3nc2NC(=O)NC(C)(C)C)c1 +CCCCCCCCCCc1cc2cn(C3CC(O)C(CO)O3)c(=O)nc2s1 +COC1C(C)CC2(Cc3ccc(C#N)cc3C23N=C(N)N(CC2CCOCC2)C3=O)CC1C +NCc1ccc(CNC(=O)C(Cc2ccccc2)NC(=O)C(N)CC2CCCCC2)cc1 +CC(C)=CCn1c2c(ccc1=O)C(NCCc1ccc(O)cc1)CCC2 +N=C(N)NCCCC1NC(=O)C2CC(NC(=O)C(CC(=O)O)NC(=O)CNC1=O)C(O)C2O +NCCNc1cc(N2CCN(C(=O)Cc3ccccc3F)CC2)nc2ccccc12 +Cc1nc2cnc3ccc(C#CCNC(=O)c4c(C)n(C)n(Cc5ccc(F)c(F)c5)c4=O)cc3c2n1C(C)C +Cn1c2c(c3ccc(-n4ccc(OCc5ccc(Cl)cn5)cc4=O)cc31)CCN1CCCCC21 +O=C(CN1CCCC1=O)NCc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +O=C(O)CC1CC(CNC(=O)CCNc2ccccn2)=CCc2ccccc21 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3cc(C4CC4)on3)n[nH]c2C1(C)C +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCC1OC(C)C(C)O1 +Cc1ccccc1N1CCN(C(=O)COc2ccc(Cl)c(N3CCN(C)CC3)c2)CC1 +CCCCCCC1(N2CCN(C(=O)C(Cc3ccc(Cl)cc3)NC(=O)CC3NCc4ccccc43)CC2)CCN(C)CC1 +Cn1cncc1CN1CC(N(CC2CCN(C(=O)c3ccccc3)CC2)S(=O)(=O)c2ccccn2)Cc2cc(C#N)ccc21 +COc1ccc(C=NNC(=O)CSc2cc(C)nc3ccccc23)cc1OC +FC(F)(F)COc1ccc(-c2ccc3nnc(C(F)(F)F)n3c2)cc1 +Cc1nc(-c2cccc(CN3C(=O)CCCC3c3ccccc3-c3ccccc3)c2)cs1 +Nc1nc(CC(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cs1 +O=c1nc(OCC2COCCO2)cc2n1CCc1ccccc1-2 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1cccc(Sc2nc3ccccc3[nH]2)n1 +COCCN(C)c1ccc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)cn1 +Cc1nc2cnccc2n1CC1CCN(C(=O)C(C)c2ccc(N)cc2)CC1 +CC(C)(C)c1cnc(CSc2cnc(NC(=O)C3CCCNC3)s2)o1 +Cc1cc(C(N)=O)nn1-c1cccc(-c2cccc(F)c2C(F)(F)F)c1 +Cn1cnc2cc(-c3ccc(F)nc3)nc(NC3CC3)c2c1=O +COc1cc(-c2nc(-c3cc(C)nc(C(F)F)c3)c3n2CC(CF)OCC3)ccc1OC(F)F +COc1ccc(Oc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1 +O=C(O)CCCCCOc1cc(-c2ccc(NC(=O)C(F)(F)F)cc2)cc(-c2ccccc2)n1 +COc1cc(OCc2csc(-c3ccno3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +COc1ccc(C2C(c3cc(OC)c(OC)c(OC)c3)C(C)=NN2C(C)=O)cc1O +COC(=O)c1ccc(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)cc1 +COc1ccc(C=CC(=O)c2ccccc2-c2ccc(F)cc2)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)C=Cc2ccc3c(c2)OCO3)CC1 +NC(Cc1nc2cc(Cl)c(Cl)cc2nc1CP(=O)(O)O)C(=O)O +O=S(=O)(NCC1CC1)c1ccc(NC2CN3CCC2CC3)cc1C(F)(F)F +O=C(Cc1cc[n+]([O-])cc1)N1CCN(C2c3ccc(Cl)cc3SCc3cccnc32)CC1 +CC(Nc1nc(Cl)cc(N2C(=O)OCC2C(C)O)n1)c1cnc(-c2ccccn2)s1 +COc1cc(C(=O)c2c[nH]c(-c3ccc(C(F)(F)F)cc3)n2)cc(OC)c1OC +CCc1nc(-c2cnc(C)cc2N(C)C)c(CC)nc1NC(CC)CC +O=C(O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)OCCCCC2CCCCC2)co1 +COc1cc(C(=O)NCCN(C)C)c(C)cc1Nc1ncc(C(F)(F)F)c(Oc2cccc3c2C(=O)N(C)C3)n1 +CC(C)C1C(=O)Nc2ccc(NC3CCCCCC3)cc2-c2nc3cc(C(=O)N4CCCN(C)CC4)ccc3n21 +Cn1cc(-c2cc(C(=O)N3CCS(=O)(=O)CC3)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +CCN1CCC(Nc2ccc(CN(CC(C)C)S(=O)(=O)Cc3ccccc3)cc2)C(F)(F)C1 +CNC(=O)c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nn1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1C(C)=O +CN(C)c1ccc(-c2nc3c(N4CCN(C(=O)Nc5ccccc5)CC4)c(Br)cnc3[nH]2)cc1 +O=C(Nc1ccc(Cl)cc1)C1CN(CCO)CC1C(=O)Nc1ccc(-n2ccccc2=O)cc1F +COc1ccc(Br)cc1CCc1c(Cl)cccc1-c1nc(C)c[nH]1 +Fc1cccc(F)c1Cc1cnc(Nc2ccc(COc3ccncc3)cc2)o1 +O=c1[nH]c2ccccc2n1C1CCN(Cc2ccc(-c3nc4cc5nc[nH]c5cc4nc3-c3ccccc3)cc2)CC1 +Clc1ccccc1Nc1nc2c(-c3nnc[nH]3)cccc2c2scnc12 +Cc1cc(C(=O)O)ccc1N1CC2(CCN(Cc3cn(C(C)(C)C)nc3-c3ccc(F)c(F)c3F)CC2)OC1=O +CC(C(=O)Nc1ccc(-c2ccccc2)cn1)n1nnc(-c2ccncc2)c1-c1ccccc1 +Cc1ccnc2c1C(=NN=C(N)N)CC(c1ccccc1Cl)C2 +Fc1cc(Nc2n[nH]c3cccnc23)cc(C(F)(F)F)c1 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+O=C1c2ccccc2S(=O)(=O)N1Cc1cccc([N+](=O)[O-])c1 +CS(=O)(=O)c1ccc(-n2cc(Cl)c(OC3CCN(c4ncc(C(F)(F)F)cn4)CC3)cc2=O)cc1 +COCCOCC#CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +COc1cc(C=Cc2nc3cc(Br)cnc3n(CC(=O)O)c2=O)ccc1O +CN1CCC(c2ccc(Cl)cc2)C(C(=O)OCCCCCOC(=O)C2CN(C)CCC2c2ccc(Cl)cc2)C1 +CCNC(=O)Nc1cn(-c2ncc(C)c(CCC(=O)O)n2)c2cc(-c3cccnc3)cnc12 +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccc(O)cc2)sc2cc(O)c3ccccc3c12 +NC(=O)c1ccc(NC2CNCCC2c2ccc(C(F)(F)F)c(F)c2)c2cncnc12 +CCCn1cc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cn1 +O=C(NS(=O)(=O)C1CC1)c1cc(C2CC2)c(OC2C3CC4CC2CC(Cl)(C4)C3)cc1F +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCCC1 +CC(C)(C)OC(=O)C(CCCCN)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1ccc(-c2ccccc2)cc1 +Cc1cc(C)cc(S(=O)(=O)NC(=O)Nc2ncc(Br)s2)c1 +O=c1n(-c2ccc(F)c(F)c2)ccc2nc(COc3ccccc3)cn12 +CC(=O)Nc1nc2ccc(-c3nn(Cc4cc5cccc(C)c5c(=O)n4C(C)C)c4ncnc(N)c34)cc2s1 +CC(C)Cc1cn(-c2nc(N)c3ncn(C4OC(COS(=O)(=O)NC(=O)c5ccccc5O)C(O)C4O)c3n2)nn1 +CCNC(=O)N1CCCN(c2ccc(C(=O)NCCc3ccc(Cl)cc3Cl)cc2NC(=O)c2ccsc2)CC1 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+O=C(O)Cc1ccc(OCC(F)(F)F)c(-c2ccc(F)c3c2CN(C(=O)CC2CCOc4ccccc42)CC3)c1 +O=C(CCN1CC=C(c2ccc(F)cc2)CC1)c1ccc(F)cc1 +Cc1cccc(CN2CCC(NC(=O)C(O)(c3ccccc3)C3CCCC3)CC2)n1 +c1ccc(-c2csc3ncnc(N4C5CCC4CC(COCCN4CCCC4)C5)c23)cc1 +O=C(O)CCCOc1ccc(-c2cc(OC3CC3)ccc2F)cc1 +CCCCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1CN1CCNCC1 +CC(NC(=O)CCN1CCC(c2ccccc2)CC1)c1ccc(Br)cc1 +Cc1ccc(-c2cc(C(=O)NC3CCCCC3)no2)cc1 +O=C(c1nc(-c2nnc(Cc3ccc(F)cc3)o2)c(O)c2ncccc12)N1CCC(O)CC1 +NS(=O)(=O)c1ccc(C#CC2CCCCN2C(=O)COc2ccccc2)cc1 +CCn1c(C(=O)NCCN)ccc1C(CC)(CC)c1ccc(OCC(=O)C(C)(C)C)c(C)c1 +CC(C)CC(O)C(O)C(CC1CCCCC1)NC(=O)C(C)OC(Cc1ccccc1)C(=O)N1CCOCC1 +O=C(NC1CCCCC1)C(c1cccnc1)N(C(=O)CCl)c1ccc(F)cc1 +CC(C=Cc1ccoc1-c1cc(C(C)C)cc(C(C)C)c1OCCCF)=CC(=O)O +O=C(c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1)N1CCCC1 +CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2C#N)cc1 +CCNCc1ccc(C(=O)Cn2ccc(OCc3ccc(Br)cn3)cc2=O)c(C)c1 +COc1ccc(C(=O)NC(c2ccccc2Cl)c2cc(Cl)c3cccnc3c2O)cc1 +NC(=O)C12CC3CC(C1)C(NC(=O)C1(NS(=O)(=O)c4cc(Cl)c(Cl)cc4F)CC1)C(C3)C2 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+N=C(N)N1CCCC(CC2C(=O)N(C(=O)N3CCN(C(=O)NCCCCc4ccccc4)CC3)C2C(=O)O)C1 +COc1cccc(OC)c1C(=O)Nc1c[nH]nc1C(=O)NC1CCC(OC)CC1 +O=C1NCCc2c1ccc1[nH]cc(CCNCc3cn[nH]c3)c21 +COc1ccccc1C(=O)NC(=O)Nc1ccc(OCC(F)(F)F)c(C(F)(F)F)c1 +COCC(C)CN1C(c2c(F)cc(C=CC(=O)O)cc2F)c2ccc(O)cc2CC1(C)C +CC(=O)NP(=O)(O)OCC1OC(n2ccc(N)nc2=O)C(F)(F)C1O +CC(C)c1c(OCC(O)CN2CCN(c3ccnc4cc(Cl)ccc34)CC2)ccc2c1CCC1C(C)(C)CCCC21C +N#CCNC(=O)C1(NC(=O)c2ccc(-c3csc(N4CCC(N5CCOCC5)CC4)n3)cc2)CCCCC1 +O=C(NO)C1CC(c2ccc(-c3ccc(F)cc3)cc2)C(=O)N1 +CC(C)(NC(=O)c1ccc(C2CCCO2)c(-c2cccc(Cl)c2)n1)c1ncco1 +CNc1ccc(-c2ccc(C(=O)NCC(C)(C)C)cc2C(=O)O)c(C(=O)Nc2ccc3c(N)nccc3c2)n1 +CNC(=O)c1cc(CSc2nc(NCCO)c(C#N)c(-c3ccc(OCCO)nc3)c2C#N)ccn1 +COc1ccc2c(c1)c(CN1CCN(C)CC1)cn2S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(C)(=O)=O)cc2)n(-c2cccc(CN)c2)n1 +O=c1cc(-c2ccc(Cl)c(Cl)c2)oc2cc(O)ccc12 +Cn1nnc(-c2ccc(F)c3c(C(=O)C(=O)N4CCN(C(=O)c5ccccc5)CC4)c[nH]c23)n1 +Cc1c(Cc2c(F)cccc2F)nc(SCc2ccccc2)[nH]c1=O +Nc1ncc(-c2nc3ccncc3s2)c(NC2CC(CO)C(O)C2O)n1 +CNc1cnn(C2CC(C)(C)CC(C)(C)C2)c(=O)c1Cl +CN1CCc2ccc(Nc3nnc(-c4cncc(-c5cccnc5)c4)o3)cc2C1 +COC(=O)Nc1n[nH]c2cc(NC(=O)NC3CCOc4ccccc43)ncc12 +CN(CCCOc1ccc2ccc(=O)oc2c1)Cc1cccc(OC(=O)NCCCCCCCN2CCOCC2)c1 +Cc1cn(Cc2ccc(F)c(F)c2)c2c(-c3cc(NS(=O)(=O)c4ccc(F)c(F)c4)no3)cc(F)cc12 +Cc1ccccc1-c1ccc(Cc2nnn(C(=O)N(C)C)n2)cc1 +Cc1nc(NC(=O)c2cc(CNC(=O)C(C)C)cnc2C(F)F)[nH]c1-c1ccc(C(F)(F)F)cc1 +Nc1nc(N2CCNCC2)c2oc3c(Cl)cc(Cl)cc3c2n1 +Cc1cc(C(=O)Nc2ccc(C3CNCCO3)cc2F)cc(C#N)n1 +O=C(Nc1ccc(C(F)(F)F)c(Cl)c1)N1CCC(F)(c2ncc(C3=NOC(CO)C3)cc2Cl)CC1 +O=C1NCc2nc(Sc3ccccc3)ccc2N1c1c(Cl)cccc1Cl +O=C(Nc1ccc(Br)c(C(F)(F)F)c1)N1CC=C(c2ncc(C(O)CO)cc2Cl)CC1 +COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(C(C)N2CCCC2)cc1 +c1cc(NC2CCNCC2)c2nc(-c3nnc4ccccn34)ccc2c1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)NCC(c2ccc(Cl)cc2)N2CCOCC2)c1 +CCNC(=O)Nc1cccc(-c2n[nH]c(C3CCCCN3C(=O)COc3ccccc3)n2)c1 +O=C(Nc1cncc(Oc2cncnc2)c1)c1cccc(Br)c1 +CSc1cc(C)nc(SC)c1NC(=O)N(Cc1ccc(Oc2ccc(F)cc2)cc1)C(C)c1ccccc1 +COc1c(Cl)cc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1Cl +c1ccc(-c2nc(NCCN3CCOCC3)c3nc(NCCN4CCOCC4)c(N4CCCC4)nc3n2)cc1 +COc1ccc2nc3cccc(C(=O)NCCCN(C)CCCNC(=O)c4cccc5nc6ccc(OC)cc6nc45)c3nc2c1 +O=C(c1cccc(Oc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1)N1CCCCC1 +O=C(NCCCc1cccc2oc(CCCCc3ccccc3)cc12)C1CC1 +Cc1ccc(NC(=O)OCc2ccccc2)c(=O)n1CC(=O)NC(C(=O)C(F)(F)F)C(C)C +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2ccc(N)nc2C#N)c(F)c1 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCCC(F)(F)F)c12 +c1ccc(CC[n+]2cc(-c3ccccc3)n3c2CCC3)cc1 +Cc1cc(-c2ccc(NC(=O)C(C)c3cccc(-c4ccc(N(C)C)cc4)c3)cc2)ccn1 +NCCOc1c(-c2ccc(N3CCCC3)c(Br)c2)[nH]c(=O)c2cc(F)ccc12 +COc1ccc(C(=O)Nc2ccc(F)c(C34COC(CF)C3S(=O)(=O)C(C)(C)C(=N)N4)c2)nc1 +NCc1cc(CC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)ccn1 +Cc1c(C(=O)N2CC=C(c3ccc(F)cc3)CC2)sc2c1[nH]c(=O)c1ccccc12 +CCC(=C(c1ccccc1)c1ccc(O)cc1)c1ccc(O)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N4CCCC4C)n3)C2)cc1 +O=C1c2cccc3c(NCCO)ccc(c23)C(=O)N1c1cccc(Cl)c1 +COc1ccc(C=NNc2[nH]nc(C)c2C(=O)Nc2cccc(OC)c2)cc1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(-c4ccc(CN5CCCC5)cc4)c3c2)cc(Cl)c1O +CC(=O)N(CCCCNc1c2c(nc3ccccc13)CCCC2)CCCNc1c2c(nc3ccccc13)CCCC2 +O=C1N=C(NCc2ccccc2Cl)SC1=Cc1ccc2ncccc2c1 +Cc1ccc(NC(=O)c2cc(C(C)(C)C)on2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)n1 +CC(O)(CSc1ccccc1)C(=O)Nc1ccc2c(C(F)(F)F)cc(=O)oc2c1 +CCC(C)(Cc1ccc(OCCCOc2ccc3c(C(F)(F)F)cc(=O)oc3c2Cl)cc1)C(=O)O +c1cc2c3cnc(Nc4ccc(N5CCNCC5)nn4)nc3n(C3CCC3)c2cn1 +NC(=O)COc1ccc2c(c1)S(=O)(=O)C=C(c1c(O)c3cc(F)ccc3n(Cc3ccc(F)cc3)c1=O)N2 +Cc1nc(NC2CCCc3ccccc32)cc(-c2ccc(O)cc2)n1 +COC(=O)CCC(NC(=O)Nc1ccc(N(C)Cc2cnc3nc(N)nc(N)c3n2)cc1)C(=O)OC +CCc1c(Cc2c(Cl)cccc2Cl)c(=O)ccn1Cc1ccccc1 +Cc1ccc(S(=O)(=O)n2c(CN3C(=O)c4ccccc4C3=O)nc3cc(Cl)c(Cl)cc32)cc1 +O=C(Oc1cncc(Cl)c1)c1cccc([N+](=O)[O-])c1 +COc1ccc(-c2cn(C3CCC3)c3ncnc(N)c23)cc1 +COc1ccccc1N1CCN(CC=CCNC(=O)c2cc3cc(OCCOCCOCCF)ccc3[nH]2)CC1 +FC(F)(F)c1cc(COCC2(c3ccccc3)CCNCC2)cc(-c2ccc3ccccc3c2)c1 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C(=O)NCCO +CCS(=O)(=O)c1ccc(-c2coc3ccc(-c4ccc(C)o4)cc23)cc1 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+CN(CCCN1c2ccccc2Oc2ccccc21)Cc1ccccc1 +CCCOc1cc(F)c(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 +COc1ncc(N2CCC(C(N)Cc3cc(F)ccc3F)CC2)cn1 +O=C(NC1COc2ncccc21)C1CCc2cc(Cl)cc(Cl)c21 +N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCC=CCOc3ccc(F)c(F)c3C(=O)N2)CC1 +Cc1nn(C)c(C)c1-c1cccc2c1CCC(N(C)C)C2 +O=C(O)c1ccc2c(c1)nc(NCCc1ccccc1)c1ccsc12 +CCOc1ccccc1N1CCN(CCCCCOc2cc(-c3ccccc3)ncn2)CC1 +O=C(Cc1ccc(-c2n[nH]c(=O)c3ccccc23)cc1)N1CCCc2ccccc21 +CC1CC2C3=CC=C(c4cncc(F)c4)C3(C)CCC2C2(C)CCNC(=O)C=C12 +NC(=S)Nc1cccc(OCCCCCCCCNC(=S)Nc2cccc(Br)c2)c1 +CC(NC1CCC(n2cc(C(N)=O)c(Nc3ccc(Cl)cc3)n2)C(C#N)C1)C1CC1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)c(NC(=O)CCC(=O)O)c2)nc2c(Cl)cc(Cl)cn12 +O=C(O)CC(NC(=O)c1ccc(Cl)cc1NC(=O)OCc1ccccc1)C(=O)CF +CC(C)(C)OC(=O)Nc1scnc1C(=O)Nc1nccs1 +CN(C)CCC1(C#N)CCN(c2c(Cl)cncc2-c2ccc3c(c2)CS(=O)(=O)N3C)CC1 +CC1(C)c2cc(C(=O)O)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +Cc1cc(=O)[nH]c2[nH]nc(-c3cccc(C(F)(F)F)c3)c12 +COC(=O)CCCCCCC(=O)Nc1ccc(Nc2ncc3cc(C(=O)N(C)C)n(C4CCCC4)c3n2)cn1 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+Cc1c(CN(C)C(=O)C=Cc2cnc3c(c2)CN(CCN2CCOCC2)C(=O)N3)sc2ccccc12 +CCN1c2cc(C)c(C)nc2N(C)C(=O)c2cccnc21 +CN=C1NC(=Cc2c[nH]c3c(Br)cccc23)C(=O)N1C +FC(F)(F)c1nc(Nc2c(Cl)cc(Cl)cc2Cl)sc1CN(CC1CC1)CC1CC1 +O=C(NC(c1ccc(Cl)c(Cl)c1)C1CCN(Cc2ccccc2)CC1)c1ccc2cnccc2c1 +CCC(CN1CCC(CNC(=O)c2ccc3cc(Cl)ccc3c2)NC(CNC(=N)N)C1=O)c1ccccc1 +O=C(O)C1COc2cc3nc(-c4cccs4)c(-c4cccs4)nc3cc2O1 +CCOC(=O)C1=C(C)NC2=C(C(=O)C(C(=O)OCC)C(c3cccc(OC)c3)C2)C1c1ccc(Br)cc1 +CCCCC(NC(=O)C(NC(=O)OCc1ccccc1)C(C)C)C(=O)C(=O)NOCc1ccccc1 +CC(C)(C)c1ccc(S(=O)(=O)N2C3CCC2CC(O)(O)C3)cc1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3sccc3-n3cccc3)CC2)nc1 +NC(=O)CN(c1ccccc1)c1cc(-c2ccc(Oc3ccc(F)cc3)cc2)cc(C(N)=O)n1 +Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2c(F)cccc2F)s1 +CC(=O)Nc1nc2ccc(CCNC(=O)Nc3ccc(C)c(Cl)c3)cc2[nH]1 +CCCOC(=O)c1ccc(NC(=O)NC(Cc2ccc(O)cc2)C(=O)NC2CCN(Cc3ccc(O)cc3)C2)cc1 +O=C(NCc1cccc(C(F)(F)F)c1)c1cc(N2CCC(N3CCCC3)CC2)cc(C(F)(F)F)c1 +Cc1nnc(NC(=O)c2ccc(-c3nc(C4CCC5CCC(=O)N5C4)n4ccnc(N)c34)cc2)s1 +CCOC(=O)c1cnn(CC(C)O)c1NC(=O)Nc1cccc(F)c1 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+O=C(O)Cn1nnc(-c2cnc(N3CCC4(CCc5ccccc54)CC3)s2)n1 +O=c1[nH]c(-c2ccc(O)c(O)c2)nc2sc3c(c12)CCC3 +CCCCCCCCCCCCCCCCOP1(=O)OCCC(C(=O)OC)=C(C)O1 +CCOc1cc2c(cc1C(=O)NC)C(=N)N(CC(=O)c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)C2 +O=S(=O)(c1ccc(Cl)cc1Cl)N1CCN(c2ncccc2C(F)(F)F)CC1 +CCc1nc2c(-c3ccc(Cl)cc3Cl)ccnc2n1C(CCOC)C1CCC1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(C(F)(F)F)cc1-c1ccn[nH]1 +N#CC(=CC1CC1)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cc(F)ccc3F)cc2)c2c(N)ncnc21 +CC1CN(c2scnc2-c2nc3c(F)cccc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21 +NS(=O)(=O)c1nnc(NC(=O)c2ccc([N+](=O)[O-])cc2)s1 +Cc1cc([N+](=O)[O-])cc(C)c1OCC1CCCN2CCCCC12 +O=C(c1ccccc1)N1CC2C(CNc3nc(-c4ccccn4)cs3)C2C1 +Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)N2CCOCC2)cn1 +C=CCN1CCC23CC(=O)CCC2(OC)C1Cc1ccc(O)c(OC)c13 +CC(C)C1(C(=O)N2CCc3ccc(C(F)(F)F)cc3C2)CCC(NC2CCc3c(O)cccc32)C1 +CC(NC1=C(C(=O)c2ccccc2)C(c2ccc(Br)cc2)N(Cc2cccnc2)C1=O)c1ccccc1 +CN1Cc2c(C3=CC4COC(=O)N4CC3)[nH]c3nccc(c23)-c2cc(F)c(F)cc21 +O=C(CCCCCN1C(=O)c2ccc(NC(=O)c3ccc(F)cc3)cc2S1(=O)=O)NO +O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)c(CCCCN3CCOCC3)cc2n1CCO +CCCOc1cc2c(cc1OC)CC(=O)N(c1ccc(OC)cc1)C2c1ccc(Cl)cc1 +Cc1cc(Nc2nc(Nc3ccc(N4CCOCC4)cc3)ncc2Br)n(C)n1 +C=C(C)C1COc2c(C)cc3oc4c(CC(O)C(C)(C)O)ccc(O)c4c(=O)c3c2C1O +O=C1NCc2nc(Sc3cc(Cl)ccc3Cl)ccc2N1c1c(Cl)cccc1Cl +O=C(NC1CCCC1Nc1ccc(C(F)(F)F)cn1)c1c(F)cccc1-n1nccn1 +O=C(NC1CCCCC1)c1ccc(C#Cc2ccccc2)nc1 +COc1cnc(COc2ccc(F)cc2F)cc1-c1cc2c([nH]1)CCNC2=O +Cc1nc2c(N3CCN(C4CCC(c5c[nH]c6ccccc56)CC4)CC3)cccc2[nH]1 +Cc1ccc(C(=O)NC2CC2)cc1-c1ccc2c(=O)cc(-c3cccs3)oc2c1 +COc1ccc(-c2nonc2NC(=O)c2cccc(C)c2)cc1OC +Oc1ccc(C2Sc3cc(O)ccc3OC2c2ccc(OCCCN3CCCC3)cc2)cc1 +CCCC(CCC)n1cc2c3c(nc(C)cc31)N(c1ccc(C(F)(F)F)cc1C(F)(F)F)CC2 +CCCCC(=Cc1cc(OCc2cc3ccccc3s2)ccc1OCc1ccc(C(F)(F)F)cc1)C(=O)O +CCCCCCn1nc(C(=O)NN2CCCCC2)c(C)c1-c1ccccc1 +C=CC(=O)Nc1cccc(N2C(=O)N(C(C)C)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +CCc1coc2ccc(-c3cc(NC(C)c4cccc(OC)c4)nc(C)n3)cc12 +COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)c[nH]c1=O)C2=O +CCNCC1CC(NC(=O)c2cc(CC)nn2C)CN1C(=O)c1coc2ccccc12 +CC(Nc1ncnc2sc(-c3cccc(C(=O)O)c3)cc12)c1ccccc1 +Cc1ccc(C(=O)NCc2cccc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCC(F)C3)nc12 +Cc1ccc(-c2cnc(C(=O)N3CCCC3)o2)cc1S(N)(=O)=O +O=c1c(-c2cccc([N+](=O)[O-])c2)nc2ccccc2n1Cc1ccccc1 +O=C(Cc1ccccc1Nc1c(Cl)cccc1Cl)NCCOc1ccc2oc(=O)ccc2c1 +Cc1cc(NC(=O)CC(=O)O)c2c(c1Oc1ccc(O)c(CCc3ccccc3Cl)c1)CCC2 +CC(=NOC(=O)Nc1cccc2ccccc12)c1ccc(-c2ccccc2)cc1 +NC(=O)c1cc(-c2ccc(F)c(Cl)c2)cc2c1[nH]c1cc(C(=O)N3CCOCC3)ccc12 +COc1cc2c(cc1OCc1ccccn1)Cc1c(-c3ccc(C#N)nc3)n[nH]c1-2 +O=C1C2Cc3c([nH]c4ccccc34)C(c3ccccc3Br)N2C(=O)CN1Cc1ccccc1 +CN(CCCNC(=O)CNC(=O)Nc1ccc2ccn(-c3ccccc3Cl)c2c1)C1CCCN(c2ncnc3[nH]ccc23)C1 +CC(C)(O)c1cc2nc(NN=Cc3cn(Cc4cccc(C#N)c4)c4ccccc34)nc(N3CCOCC3)c2s1 +CN1C(=O)C(NC(=O)CCc2ccc(Cl)cc2Cl)N=C(c2ccc(C(N)=O)cc2)c2ccccc21 +CC1CC2CSC(N)=NC2(c2cc(CNCC(F)(F)F)c(F)cc2F)CO1 +O=C1CN(Cc2cn3cc(-c4cccc(O)c4)nc(N4CCOCC4)c3n2)CCN1 +COc1cc(C=c2sc3nc(-c4cccc(Cl)c4)cn3c2=O)cc(OC)c1O +COc1cccc(-c2cccc(C3(c4ccncc4)N=C(N)N4CC(F)(F)CN=C43)c2)c1F +CC(C)C1NC(=O)CC2C=CCCSSCC(NC1=O)C(=O)NCc1[nH]c3ccccc3c1CC(=O)O2 +CC1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)C1 +N#CC1(c2cc(-c3cnc(N)c(OC(F)F)c3)nc(N3CC4CC3C4)n2)CCC1 +Cn1c(-c2cccc(N3CCc4sc(C(=O)Nc5ccc(Br)cc5)cc4C3)c2)nc2ccccc21 +CN1CCN(Cc2ccc(NC(=O)c3n[nH]cc3Nc3ncnc4ccsc34)cc2)CC1 +COCCCc1cc(CN(C(=O)C2CNCCC23OCc2cc(F)c(F)cc23)C2CC2)cc(OCCOC)c1 +COc1cccc(OC)c1Oc1nc(N)nc(Nc2ccc(C#N)cc2)n1 +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(NC2CCCCC2)C1 +COc1ccc(C2=NNC(=O)C2=NNc2ccccc2)cc1OC +COc1ccc(C(=O)Nc2ncc(Cc3ccc(F)c(C(F)(F)F)c3)s2)cc1OCCO +Cc1c(N2CC(C)(C)CCC2=O)nc2cc(F)cc(F)c2c1N1CC2(CCOCC2)c2ncc(N3CCOCC3)cc21 +CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OC(F)(F)O5)CC3)c(F)cc2n1CC[N+](C)(C)C +COc1ccc(S(=O)(=O)n2cc(C3CCN(C)C3)c3ccccc32)cc1OC +O=C(c1cccc(Cl)c1)N1CCc2oc(-c3ccc(F)cn3)nc2C1 +Cc1cc(C2CCN(C(=O)C3CN(C(C)(C)C)CC3c3ccc(F)cc3F)CC2)n(-c2cccc(Cl)c2)n1 +O=C(Cc1cccc(C(F)F)c1Cl)NC1COc2ncccc21 +CC(C)(C)c1cc(NC(=O)Nc2cc(Cl)cc(Cl)c2)n(-c2ccc(Br)cc2)n1 +CCCc1sc(NN=Cc2ccccn2)nc1-c1ccc(Br)cc1 +CS(=O)(=O)c1ccc(-c2cnc3ccc(-c4cccc(C(F)(F)F)c4)nn23)cc1 +O=C(NC1C2CN(CCc3ccc4c(c3)OCO4)CC21)C(O)(c1ccccc1)C1CCCC1 +O=C(Nc1ccccc1)C(C1CCCCC1)n1c(-c2ccc(Cl)cc2)nc2ccccc21 +CCOC(=O)C1=C(C)NC(OCC)=C(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1 +O=C(c1ccc(Nc2nc3ccccc3n3nnnc23)cc1)N1CCN(c2ccccn2)CC1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)NCc1nc2ccccc2o1 +CC(C)Oc1cc(-c2cc(C3CCN(C4COC4)CC3)n(C3CCC(F)(F)C3)n2)cnc1N +Cc1nc(O)c2cc(CSC(=S)N3CCN(c4ccc(F)cc4)CC3)ccc2n1 +CN(C)CCNCC(=O)C(O)(c1ccccc1)C1CCCCC1 +Brc1cnc(Nc2ccc3[nH]cnc3c2)nc1NC1CCc2ccccc21 +CC(C)(C)C1(O)CCN(CC2c3ccccc3CCc3ccccc32)CC1 +CCN1CCC(NC(=O)c2ccc(Nc3ncc(C(F)(F)F)c(Oc4cccc5c4C(=O)N(C)C5)n3)c(OC)c2)CC1 +COc1cc2cc(C(=O)CCC3CC[N+](C)(Cc4ccccc4)CC3)sc2cc1OC +O=C1CCN1c1cc(Cc2n[nH]c(=O)c3cccnc23)ccc1F +O=C(OCC#CCOC1=C(OCC#CCOC(=O)c2ccccc2)C(=O)c2ncccc2C1=O)c1ccccc1 +CN(C)Cc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CNC(=O)C(Cc1ccccc1)NC(=O)C(CSC)NC(=O)CS +O=C(NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)NC1(C(=O)O)CC1 +COc1cccc(C(CN)Nc2ncnc3c(C(N)=O)cccc23)c1 +COc1ccc(-c2cc(F)ccc2N2CCN(CCCCCC(=O)NCc3ccc(C#N)cc3)CC2)cc1 +COc1cc(OC)cc(N(CC#CC2(O)CCNC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +COc1ccc(Nc2cccnc2-c2nc(C)nc(N)n2)cn1 +O=C(OCC#CCSc1nnc(-c2ccc3ccccc3c2)o1)c1ccc(F)cc1 +COc1cccc(NC(=O)c2ccc3cc(C(=N)N)ccc3c2)c1 +COc1cc(NS(=O)(=O)c2ccc(NC(=S)NC(=O)C=Cc3ccc(F)cc3)cc2)ncn1 +[C-]#[N+]c1ccc(Cn2c(CC3(C(=O)O)CCCC3)nc3cc(OCc4ccc5ccccc5n4)ccc32)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4csc(CN5CCCC5)c4)nc23)N1 +CNC(=O)C1OC(n2cnc3c(NC4CC(C)(C)NC(C)(C)C4)ncnc32)C(O)C1O +CNC(=O)NCC1CC1c1cccc2c1OC(C(C)C)N2 +OC(CN1CCN(c2ccccc2)CC1)Cn1nc(-c2ccccc2)c2c1CCNC2 +COc1ccc(Nc2nc(-c3cccc(C(=O)Nc4ccc(CC(=O)O)cc4)c3)cn3ccnc23)cc1OC +CCOC(=O)C=CC(=O)N(CC(N)=O)NC(=O)C1CCCN1C(=O)C(NC(C)=O)=C(C)C +O=C1C(=Cc2cccc3cnccc23)CCC1=Cc1cccc2cnccc12 +CCN1CCN(S(=O)(=O)c2cnc(OCCOC)c(-c3nc4c5n(nc4c(=O)[nH]3)CCCC5)c2)CC1 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+CCN1CCC(Oc2ccc(C(=O)Nc3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)nc2)CC1 +O=C1c2ccccc2-c2c1c(NCCN1CCCCC1)nc1ccc(Cl)cc21 +CCOc1cc(C(=O)O)nc2ccc(-c3ccc(OCc4c(-c5c(Cl)cccc5Cl)noc4C(C)C)cc3)cc12 +CCC(C)N(Cc1ccccc1C(F)(F)F)C(=O)C1CCN(S(=O)(=O)c2ccc3[nH]ncc3c2)CC1 +CCC(=O)Nc1cccc(C(=O)Nc2cccc(Nc3cc(-c4c(-c5ccc(F)cc5)nc(SC)n4C)ccn3)c2)c1 +CCCCCCCCc1ccnc(N2CCc3cc(S(=O)(=O)Nc4ccccc4)ccc32)n1 +CC(C)(C)Cc1ccc(S(=O)(=O)N2CCC(NCC(O)COc3cccc4[nH]c5ccccc5c34)CC2)cc1 +Cc1cc(-c2ccncc2)cc2[nH]c(C3COc4ccccc4O3)nc12 +CC(C)(C)Nc1nc2cc(Cl)c(Cl)cc2nc1S(C)(=O)=O +COC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C2c3cc(F)cc(F)c3CC2O)C1 +C[N+](C)([O-])c1ccnc2sc3c(=O)n(C4CCCCCC4)cnc3c12 +CN(C)CCCN1CC(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +NC1CC2(CCN(C(=O)c3cc(NC(=O)c4cc(-c5ncccc5F)c(Cl)cc4Cl)n(-c4ccccc4)n3)CC2)C1 +COc1ccc(NC=CC(=O)c2cc(OC)c(OC)c(OC)c2)cc1Cl +CN(C)c1ccc(C=NNc2ncnc3scc(-c4ccc([N+](=O)[O-])cc4)c23)cc1 +CS(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CCC4(CC3)OCCO4)cc2C(N)=O)cc1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(N2CCN(c3cccc(F)c3)CC2)cc1F +CNc1ncnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +CN1C(=O)CN=C(c2ccccc2)c2cc(C#N)ccc21 +C#CCOc1ccc2c(C3=C(c4cn(C)c5ccc(Br)cc45)C(=O)NC3=O)coc2c1 +CCCN(CCC)c1c(OC)nn2c(-c3c(OC)cc(COC)cc3OC)csc12 +O=C(c1ccc(O)nc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +CCCCCCCCCCCCCc1ccc(NC(=O)Nc2c(C(C)C)cccc2C(C)C)cc1 +Cc1cc(-c2cc(C)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ncco5)ccc43)cc2F)ccc1Cl +CCN(C(=O)c1cc(C)ccc1-n1nccn1)C(C)Cn1nnc(-c2ccc(F)cn2)n1 +O=C1COc2c(Cl)cc(Cl)cc2N1Cc1nnc(CCc2ccc(Cl)cc2)n1CCC(F)(F)F +CCc1ncnc(-c2ccc(C(=O)N3CCN(O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +Cc1cccc(C(=O)O)c1Oc1nc(Oc2cccc(-c3cccc(CN)c3)c2)c(F)cc1F +O=c1oc2cc(OCCN3CCN(Cc4ccccc4)CC3)ccc2c2ccccc12 +CN1c2ccc(F)cc2C(=O)N(C2CCN(CCCn3ccnc3-c3ccccc3)CC2)C1c1ccccc1F +O=C(CNC(=O)Nc1ccc2cnccc2c1)NC1CCCC1 +Nc1nc(N)c2nc(CNc3ccc(Cl)cc3Cl)ccc2n1 +COc1cc(C=CC(O)=CC(=O)C=Cc2ccc(OCc3ccccc3)cc2)ccc1O +CCc1c(C(=O)c2cc(C)cc(C)c2)n(CCC2C=CCC2)c(=O)[nH]c1=O +O=C(Cn1nnc(-c2ccncc2)c1-c1ccccc1)Nc1ccc(-c2ccoc2)cn1 +CC(O)(CS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CC(=O)NC(C)c1ccc(OC2CN(c3cccc(C(F)(F)F)c3)C2)cc1 +c1ccc(-c2csc3nc(OC4CC5CC4CN5)nc(N4C5CCC4COC5)c23)cc1 +CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)Cc2cnccn2)ccc1Oc1ccc(F)cc1F +O=C(OC1CC2(N3CCCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2)c1ccccc1 +CC(C)Oc1ccc(C=NNC(=O)C(CSCc2ccccc2)NC(=O)c2ccc([N+](=O)[O-])cc2)cc1 +CC#CC(C)(O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 +O=C(Nc1nc2c(s1)CC(N1CCOCC1)CC2)c1cccc(CNC(=O)c2csc(-c3cccnc3)n2)c1 +CCOC(=O)C1C(c2ccc(-c3cccn3CC)cc2)CC2CCC1N2C +O=C1NCc2cc(F)c(OCCCN3CCN(c4cccc5ccccc45)CC3)cc21 +Cn1c(=O)c(-c2c(Cl)ccc(O)c2Cl)cc2cnc(Nc3ccccc3)nc21 +Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccccn4)cc3=O)cn12 +C=CC(=O)N1CC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccc(Cl)cc5)cc4)nn32)C1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1CCOc2ccc(OC(C)C)cc21 +Cc1cc(=NCCC2CCN(Cc3ccccc3)CC2)[nH]nc1-c1ccccc1 +CC12Cc3cnn(-c4ccccn4)c3C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(=O)CSc1nc2ccccc2s1 +COc1cnc(C(=O)Nc2ccc3c(c2)C2(COC(N)=N2)C2(CC2)C(C)(C)O3)cn1 +CCCc1cc(OC)nc2nc(C(=O)c3ccccc3)cn12 +CC#CCOc1ccc(S(=O)(=O)NC(Cc2c(C)n(Cc3cccc(F)c3)c3ccc(OC)cc23)C(=O)O)cc1 +N=C(NCc1ccccc1)c1ccc(OC(F)(F)F)cc1 +O=C(NC1CCN(Cc2ccc3cc(F)ccc3c2)CC1)c1ccc(F)cc1 +CCOc1ccc(-c2nc(C)sc2-c2cc(OC)c(OC)c(OC)c2)cc1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC(C)O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +CC(NC(C)(CCc1ccccc1)C(=O)O)C(=O)N1CCCC1C(=O)O +Cc1nn(CCC(F)(F)CO)c(-c2ccc(F)cc2)c1-c1ccc2c(c1)NC(=O)CO2 +CC1(C)CC(O)(COc2ccc(C3CCC4(CC3)OOC3(O4)C4CC5CC(C4)CC3C5)cc2)CC(C)(C)N1 +Cc1cc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5ccc(Cn6cccn6)cc5)nc34)CC2)no1 +N#Cc1cc(-c2ccnc(Nc3ncc(C4CCNCC4)cn3)c2)ccc1OC1CCOCC1 +O=C(NC(Cc1ccccc1)C(O)CC1(Cc2ccccc2)N=CC(C2CNC(=O)c3ccccc32)=C1O)OC1CCOC1 +Cc1ccc[n+](C(C)C(=O)c2ccc(-c3ccccc3)cc2)c1 +COC(=O)C1(Cc2cccc(F)c2)NCc2cnc3c(-c4ccc(C(F)(F)F)cc4)c(C(N)=O)nn3c21 +COc1cccc2c(=O)[nH]c(-c3ccc(C)cc3)cc12 +NS(=O)(=O)c1ccc(NC(=O)CCCCN2CCOCC2)cc1 +COc1ccc(-c2ccc[nH]c2=O)cc1C(C)(C)C +CCC1CN(C(=O)Nc2ccccc2)c2ccc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)cc2O1 +CS(=O)(=O)N1CC=C(c2cc3cc(C4CCN(c5ccc(C(F)(F)F)cn5)CC4)oc3cn2)CC1 +COc1ccc2cc(-c3cc(C(F)(F)F)nn3C(C)c3ccc(C(=O)NCCC(=O)O)cc3)ccc2c1 +CCCCN1CCN(c2ccc(S(=O)(=O)Oc3cc(OC)c(OC)c(OC)c3)cc2)C1=O +N=C(N)c1ccc(O)c(CN2CCC(NS(=O)(=O)c3cc4c(Cl)nccc4s3)C2=O)c1 +N#Cc1nc(NC2CCCCC2)c(N)c(N2CCOCC2)n1 +CC(C)(C)CCN1C(=O)C(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)SC1c1c(F)cccc1F +CC(C)CC(NC(=O)CCN(C)C)c1cc(C(F)(F)F)ccc1N1CCN(C(=O)C2CSCC2c2ccc(Cl)cc2)CC1 +CCCCCc1ccc(-c2nnc(-c3ccccc3C(F)(F)F)n2C)cc1 +COc1ccc(C(=O)n2c(C)c(Cc3cccc(OC(C)C(=O)O)c3)c3cc(OC(F)(F)F)ccc32)cc1 +CC(O)C(NC(=O)Nc1cc2[nH]nc(OCCOC(F)F)c2cn1)c1ccc(F)cc1 +Nc1c(-c2nc3cc(N4CCOCC4)ccc3[nH]2)c(O)nc2ccncc12 +Cn1nccc1-c1cc(C(F)(F)F)ncc1Oc1ccc(S(=O)(=O)Nc2cscn2)cc1C#N +Cc1c(N(CCC2CC2)S(=O)(=O)c2ccc(N3CCOCC3)cc2)sc2ccccc12 +Cc1n[nH]c2nc(-c3ccccc3)c(C#N)c(-c3ccccc3)c12 +CC(C)S(=O)(=O)N1CC2CC=C(c3ccc(CCN4CCCC4)cc3)C2C1 +CCCOC(=O)N1CCc2c(nc(CC(C)(C)C)n2CC2CC2)C1 +COCCCOc1cc(C(C)N(C(=O)C2CNCCO2)C2CC2)cc2ccoc12 +NS(=O)(=O)c1ccc(OCCCN2CCC(C(O)(c3cccc(F)c3)c3nccs3)CC2)cc1 +CCc1nc2c(C)ccnc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +N=c1oc2ccccc2cc1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CN(c1nc2ccc(Cl)cc2s1)C1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 +Cc1cc(CCC(=O)O)ccc1OCc1cccc(Oc2ccccc2)c1 +CC#CCC(C)C(O)C=CC1CC(F)(F)C(=O)N1CCCCCCC(=O)O +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4cnco4)o3)cc2Cl)CS1(=O)=O +CC#CCC(O)(c1ccc(N2CCN(S(=O)(=O)c3ccc(N)nc3)CC2C#CC)cc1)C(F)(F)F +Cc1cccc(S(=O)(=O)n2cc(NC(=O)c3nccs3)cn2)c1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(-c3ccccc3)n[nH]c2C1 +CCCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(Cl)cc3Cl)ccnc21 +Cc1ccc(-c2ccc(C=C3SC(=S)N(C)C3=O)o2)cc1Cl +CCC(C)C(S)C(=O)NC(C(=O)N1CCCC1C(=O)O)C(C)C +CCCCOc1ccccc1N1CCN(CCCN2C(=O)C3CCCN3C2=O)CC1 +COc1ccc(C=Cc2nnc(NC(=O)c3ccccc3OC)s2)cc1OC +NC(=O)Nc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(F)cc2)ccn1 +COc1ccccc1N1CCN(CCCCCC(=O)NCc2ccc(C#N)cc2)CC1 +CC12CCC3C(CC(O)C45CC4CCC35C)C1=CC=C2c1cccnc1 +O=S(=O)(c1cc(Cl)c2oc3c(c2c1)CNCC3)n1ccc2ccccc21 +NC(=O)c1cc(C(O)CO)nc(-c2ccc(Oc3cc(Cl)ccc3F)cc2)n1 +Cn1c(Nc2ccc(C(=O)NCCCCCCC(=O)NO)cc2)nc2ccccc21 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CC3CC1CC(CC(=O)O)(C3)C2 +O=c1c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc2n1NC1CCCCC1 +O=C(NC1CCN(Cc2ccc3c(c2)OCCO3)CC1)c1cc(=O)c2ccc(F)cc2o1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCN2CCOCC2)CCCC1)c1ccc2ccccc2c1 +Cc1cc(CN(CC2CCCC2)C(CC(=O)O)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CN(C)C1=O +CS(=O)(=O)c1ccc(-c2sc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1 +CN(C)CCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1 +CCCN(CCC)C(=O)c1c(C)c2c(C(=O)OCC)ncn2c2ccccc12 +Cc1ccc(C(=O)NC2CC2)cc1Oc1nncc2c1cnn2-c1c(F)cccc1F +CN(C)CC(=O)Nc1ccc2c(-c3c(-c4ccccn4)nn4c3CCC4)ccnc2c1 +CC(C)(Cc1cccc(CC(=O)NCc2ccc(Cl)c(Cl)c2)c1)NCC(O)c1ccc(O)c(NS(C)(=O)=O)c1 +CCN1C(=O)c2cccc3c(S(=O)(=O)Nc4cccc(C(C)=O)c4)ccc1c23 +C=CC(=O)Nc1cccc(CSc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2Cl)c1 +COCc1csc(-c2nc(C(C)(C)C)nc3nc(N)c(C#N)c(N)c23)n1 +OC1(C(F)(F)F)CCc2c1[nH]c1cc(Cl)c(Cl)cc21 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1ccnc(N2CCOCC2)c1 +COc1ccc(-c2cc(C(N)=O)nc3cc(CCc4cncnc4N)ccc23)cc1 +CCc1c(-c2nnc(C(C)(C)C)o2)nc(-c2ccccc2Cl)n1-c1ccc(Br)cc1 +Cc1cccc(Nc2ccccc2C(=O)NCCC(=O)NCCCCNc2c3c(nc4ccccc24)CCCC3)c1C +O=C(CCCCCCCCn1cc(-c2cccnc2)nn1)NCC(c1ccccc1)c1ccccc1 +COc1ccc(NS(=O)(=O)c2ccc(Br)c(C)c2)cc1N1CC(C)NC(C)C1 +O=C(Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1)N1CCN(c2ccc(Cl)cc2)CC1 +Cn1c(=O)c2c(cc(OCc3ccc(Cl)c(C(F)(F)F)c3)n2C)n(C)c1=O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CN4CCC(N5CCCCC5)CC4)c(O)ccc3nc2-1 +CCC(C)(C)C1CCC(N2CCC(N3C(=O)Cc4ccccc43)CC2)CC1 +CC(=O)c1ccc(-c2cccc(-n3cc(C(=O)NC(C)C)c(=O)c4cccnc43)c2)cc1 +COc1cc(OC)cc(-c2c[nH]c3ncc(-c4cccc(N)c4)cc23)c1 +Cc1ccc(-c2c(=O)n(CCCCN3CC=C(c4c[nH]c5ccc(Br)cc45)CC3)c(=O)n3ccccc23)cc1 +COc1ncc(Nc2ncc(C(C)(C)N3CCOCC3)cc2-c2nc(C)nc(N)n2)cc1F +COc1ccc2ccc3oc(CCNC(=O)C4CC4)cc3c2c1 +CNC(=O)CN1CCC2=C(C1)c1c(O)cc(C(C)CCCc3ccc(F)cc3)cc1OC2(C)C +N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)cc3O)o2)nc1 +CCc1ccnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +O=S(=O)(c1ccc2cc[nH]c2c1)N1CCCC1CCN1CCC(c2cc3ccccc3[nH]2)CC1 +O=C(O)CCCOc1ccc(-c2ccc(-c3ncc(C(F)(F)F)[nH]3)cn2)cc1 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1cnc(N(C)Cc2cccc(C(=O)O)c2)c(Cl)c1 +CCCN(c1cc(C(=O)Nc2ncc(CC(=O)O)s2)cc2c1OCO2)S(=O)(=O)c1cc(Cl)ccc1OC +CCCn1c(=O)c2nc(C34CC5CC(CC3C5)C4)[nH]c2n(CCC)c1=O +O=c1cc(-c2ccccc2)oc(O)c1C(SC1CCCCC1)c1ccccc1 +O=C(CCS(=O)(=O)Cc1ccccc1)Nc1nnc(C(F)(F)F)s1 +COc1ccc(N2CCN(CC(O)c3ccc(O)c(C(N)=O)c3)CC2)cc1 +CCCn1c(=O)c2[nH]c(-c3cn[nH]c3)nc2n(CC)c1=O +CN(C)C1CCN(c2cc(-c3c(N)nn4cccnc34)ncn2)C1 +Cc1cccc(NC(=O)C=Cc2cccc([N+](=O)[O-])c2)c1 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)N1CC=C(c2ncc(C(O)CO)cc2Cl)CC1 +CN(C)c1nc(C(F)(F)F)nc2c1ncn2Cc1ccc(Cl)cc1[N+](=O)[O-] +CC1C2CCC3C4CC=C5CC(N(C)C(=O)c6ccccc6)CCC5(C)C4CCC32CN1C +CCN(CC)CCNc1n[n+]([O-])c2ccc(Cl)cc2[n+]1[O-] +COc1ccccc1-c1csc(Nc2ccc3c(c2)OCO3)n1 +Cc1cccc2c1cc(C(=O)NCc1ccc([N+](C)(C)C)cc1)n2Cc1cccc(C(=N)N)c1 +CC1CC(NC(=O)CCc2nc(-c3ccc(O)cn3)no2)=C(C(=O)O)CC1c1cccc(F)c1 +Cc1cc(-c2nc(-c3cnc(OCC4COC(=O)N4)c(C)n3)no2)cc(NC(C)C)n1 +CC(C)(C)OC(=O)N1CCC(c2cc3cc(-c4ccc(NS(C)(=O)=O)cc4)ncc3o2)CC1 +Cn1c(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)nnc1-c1ccco1 +COC(=O)C1=C(Nc2cc[nH]n2)OC(=Cc2c[nH]c3ncccc23)C1=O +CCOC(=O)c1ccc2nc(-c3cccnc3)c3c(c2c1)NCCC3 +Nc1n[nH]c2cc(NC(=O)NCc3ccccc3OC(F)F)ncc12 +N#CCNC(=O)c1ccc(-c2ccnc(Nc3ccc(N4CCSCC4)cc3)n2)cc1 +Cn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1C1CC(N)CCO1 +CNC(=O)C1CCCCN(C)C(=O)COC(C(=O)NO)C(CC(C)C)C(=O)N1 +CC(C)Oc1ccc(OCC2c3ccc(OC(C)C)cc3CCN2C(=S)c2cccc(Cl)c2)cc1 +O=CC(Cc1ccccc1)NC(=O)C1CCCN1S(=O)(=O)c1ccccc1[N+](=O)[O-] +COc1cc(CNC(=S)NC(CCc2ccc(C(C)(C)C)cc2)COC(=O)C(C)(C)C)cc(Br)c1O +COc1cc(NC(C)CCCNCc2ccc(COC3OC4OC5(C)CCC6C(C)CCC(C3C)C46OO5)cc2)c2ncccc2c1 +COc1cc2ncnc(Nc3ccc(-c4nc5ccccc5s4)cc3C)c2cc1OC +O=C(O)c1cnn(-c2cnc(NC(=O)C(OC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)c1 +O=C(c1ccco1)N1CCN(c2c3c(nc4cc(-c5ccc(F)cc5)nn24)CCC3)CC1 +COc1c(C)n(OC)c2c(c1=O)C(CCCCCc1ccccc1)CCC2 +CC12CCC3c4ccc(O)cc4CCC3C1CCC2NS(=O)(=O)c1cccc(F)c1 +O=CC(Cc1c[nH]c2ccccc12)NC(=O)CCc1ccccc1 +Nc1nnc(-c2ccc3[nH]cc(-c4cncc(N5CCCCC5)n4)c3c2)s1 +Cc1cc(C)c(NC(=O)Nc2cc3ccccc3cc2C(=O)NC2(C(=O)O)CCCCCC2)c(C)c1 +COCCOC1CN(C(=O)c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)C1 +Cc1cc(-c2ccccc2)cc(-c2ccccc2)[n+]1CCc1ccc(S(N)(=O)=O)cc1 +CNC(=O)Nc1sc2ccccc2c1C(=O)N1CCC(N2CCCC3(C2)C(=O)N2CCCCCN2C3=O)CC1 +COc1ccc(-c2[nH]c3ncc(Cl)cc3c2-c2cccc(CNC(C)=O)c2)cc1 +O=C(Nc1cc(C(=O)N2CCN(C3CC3)C(=O)C2)nn1-c1ccccc1)c1cc(-c2ccccn2)c(F)cc1Cl +Cc1cc(C)c(-c2nc3c([nH]2)CCN(C)CC3)cc1C(=O)N1CC(c2ccc(C#N)cc2)C1 +CN(C)S(=O)(=O)NC(=O)c1ccc(OCC23CC4CC(CC(C4)C2)C3)c(C2CC2)c1 +COC(=O)C(C)c1ccc(C)c2ccc(C(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)nc12 +OC(CNCCC(Oc1ccc(C(F)(F)F)cc1)c1ccccc1)COc1ccccc1C1CCCC1 +NS(=O)(=O)c1nc2ccc(OS(=O)(=O)C(F)(F)F)cc2s1 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)NC(CCNC(=O)OCc1ccccc1)C(=O)O +CCCCCC(=O)Nc1ccc2c(c1)CC(CO)NC(=O)C(C(C)C)N2C +c1ccc(-c2c(-c3ccc4[nH]ncc4c3)nc3ncccn23)cc1 +Cc1[nH]cnc1Cc1nc(-c2cccc3cccnc23)cs1 +O=C(C1CCOCC1)N1CCC(Nc2ncnc3c2CN(c2cncc(C(F)(F)F)c2)CC3)C1 +CCOc1ccc(CC(NC(=O)c2ccccc2)C(=O)N(C)C(Cc2ccccc2)C(=O)NCc2ccc(CN)cc2)cc1 +Cn1cc2c(n1)Nc1ccc(F)cc1N=C2N1CCN(CC2CC2)CC1 +Cc1c(C(C)C)c(=O)on1C(=O)N(C)c1ccccn1 +O=C(O)C(CCN1CCC(O)(c2ccc(Cl)c(C(F)(F)F)c2)CC1)(c1ccccc1)c1ccccc1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCc2c(nc(C(F)(F)F)nc2-c2ccn[nH]2)C1 +CN1CC(=O)N(CC(=O)NCc2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)C1=O +O=C1C=C(c2ccc(F)cc2)OC12CCN(CCc1ccccc1)CC2 +CCOC(=O)c1c(-c2cccc(-c3ccccc3)c2)[nH]c2cc(OC)c(OC)cc2c1=O +CN(C(=O)c1ccccc1)c1ccc2c(c1)[nH]c(=NC(=O)c1cocn1)n2CCC(N)=O +N=C(N)Nc1ccc(C(=O)Oc2ccccc2C(N)=O)cc1 +Nc1ncc(-c2cc(C3C4COCC43)n(C3CCCC3)n2)cc1Cl +C[S+]([O-])c1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc1 +CCN1CCC(N(CC)c2cc(OC)cc3c(=O)cc(C(=O)Nc4ccc(N5CCOCC5)cc4)[nH]c23)C1 +O=C1C(O)=CC(=Nc2ccc(Cc3ccncc3)cc2)c2ccccc21 +COc1ccc(CNC(=O)c2cc(-c3cncc(C)c3)ncc2-c2ccccc2F)nc1OC +COc1cc2c(cc1OC)-c1cc3ccc(OC)c(OC)c3c(=O)n1CC2 +CCN(Cc1cc(C(F)(F)F)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccc(Cl)cc1 +CC1CCN(c2ncnc3[nH]cc(-c4cccc(C#N)c4)c23)CC1 +CN1CCC2(C)c3cc(OC(=O)Nc4ccccc4Br)ccc3N(C)C12 +COc1ccccc1-c1cc(OC)c(-n2c(=O)ccc3cc(S(=O)(=O)Nc4ccon4)ccc32)cc1F +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)cc1F)Nc1cc(C(F)(F)F)ccc1F +CCCOCCn1c(=O)c(NCC(=O)NC)nc2ncc(-c3ccc(OC)nc3)cc21 +N=C(CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O)c1ccccc1N +CN(C)CCN1C(=O)c2cccc3c2c(cc2[nH]c(-c4ccccn4)nc23)C1=O +Cn1cc2c3cc(Br)ccc3nc-2c2cc(Cl)cc(F)c21 +Brc1cccc(Nc2ncnc3cnc(NCCN4CCOCC4)cc23)c1 +O=C(O)c1ccc2c(c1)C(SCCN1CCN(c3ccc(F)cc3)CC1)c1ccccc1CO2 +Cc1c(C(=O)NCCN2CCOCC2)[nH]c2cnnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12 +O=C(O)C(=O)C=C(O)c1cn(Cc2ccccc2)c(=O)[nH]c1=O +CCCn1c(=O)[nH]c2[nH]c(-c3ccc(S(=O)(=O)O)cc3)nc2c1=O +CCN(c1cc(-c2ccc(C)nc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +Clc1cccc2[nH]cc(CCCN3CCN(c4cccc5c4OCCO5)CC3)c12 +CC(=O)ON=C1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc21 +CC(=O)N1CCN(CC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +CC=CC=CC=CC[N+](C)(C)CCCCCCCCCCCCC +Nc1sc(-c2c(F)cccc2F)nc1C(=O)Nc1cnccc1N1CCC(F)CC1 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+Cc1nc2sc(C(=O)NCc3cccnc3)c(N)c2c(C)c1Cl +CCNc1nc2cc(OC)c(Cl)cc2nc1NCCCN1CCCC1 +CCc1ccccc1NC(=O)CCN1CCN2Cc3ccccc3CC2C1 +O=c1c(-c2ccc(F)cc2)c2ccccn2c(=O)n1CCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1 +O=C(c1ccco1)N1CCN2C(=O)c3ccncc3C12c1ccc(Cl)cc1 +COc1cccc(S(=O)(=O)N(Cc2ccc(N3CCN(C(C)=O)CC3)cc2F)C2CCC2)c1 +O=C(NO)c1cnc(NC2(c3cc(F)cc(F)c3)CC2)nc1 +Cc1cc(C)cc(N(C(=O)CSc2nnc(-c3ccoc3C)n2Cc2ccco2)c2ccccn2)c1 +O=C(O)C1CCCN(CCCC=Cc2ccccc2-c2ccc(F)cc2F)C1 +CNC(=O)CC1COc2cc(Br)ccc2N1C(=O)c1ccc2c(c1)NC(=O)CO2 +CNc1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c(C)c2)ncn1 +CCn1c(C(=O)NC(C)C(=O)O)ccc1C(CC)(CC)c1ccc(OCC(O)C(C)(C)C)c(C)c1 +CN(Cc1nc2c(N3CCOCC3)nc(-c3ccncc3)nc2n1C)c1ncc(C(=O)NO)cn1 +O=C1NC(CS)C(=O)N(CC2CCCCC2)C1CC1CCCCC1 +COC(=O)c1c[nH]c2cc(CN3CCN(Cc4ccc(OC)cc4)CC3)ccc2c1=O +CC(C)C1C(=O)N(S(C)(=O)=O)C2CCN(C(=O)C3CN(CC(C)(C)C)C3)C12 +O=C1c2ccccc2CCCN1CCN1CCC(n2ccc3ccccc32)CC1 +COc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Nc2ccc(C)cc2)CC1 +CC(C)(C)S(=O)(=O)N(CCCCCCN1CC(O)C(O)C(O)C1CO)C1CCCCC1 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+c1ccc2c(CC(COc3cncc(-c4cc5ccncc5s4)c3)Nc3cc4ccncc4s3)c[nH]c2c1 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(Cc1cccc(C(F)(F)F)c1S)CC(C)C +CCc1c(C(=O)NC(Cc2ccccc2)C(=O)C(N)=O)oc2ccccc2c1=O +CS(=O)(=O)c1ccc(C(=O)N2CCN(c3ccc(OC4CCN(C5CCC5)CC4)cc3)C(=O)C2)cc1 +CCC1Cc2n[nH]cc2CN1S(=O)(=O)c1ccc(Cl)cc1 +O=c1ccoc2ccc(OCc3ccc(C(F)(F)F)cc3)cc12 +NS(=O)(=O)c1cccc(-c2n[nH]c3ccc(NS(=O)(=O)c4cccs4)cc23)c1 +COc1ccc(N2CCN(C(=O)CN(C)C)CC2)cc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +COc1ccc2nc3cc(Cl)ccc3c(NCCCSCC3CCCN4CCCCC34)c2c1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1cccc(CN2CCCCC2)c1Cl +CC1(c2cc(NC(=O)c3ccc(C#N)cn3)ccc2F)COC(C)(C(F)(F)F)C(N)=N1 +Cc1ccc(NC(=O)c2cccc3ccccc23)c(=O)n1CC(=O)NC(CC(=O)O)C(=O)COc1ccccc1 +CCOc1cccc(F)c1C1CC(C)C(=O)N1Cc1cccc(-c2ncc(C)s2)c1 +COc1cc(OC)cc(N(Cc2ccc(Cl)s2)c2ccc3ncc(-c4cnn(CCO)c4)nc3c2)c1 +CCCCc1nn(Cc2cccc(C(=O)OC)c2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(c1ccccc1)N1CCC(CCCCn2cc(-c3ccccc3)nn2)CC1 +CCCCOC(=O)c1cc(NC(=O)c2cnc(Cl)nc2C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ccc2ccc3c(C#N)cc(C(=O)c4ccccc4)n3c2c1 +CCCCc1nnc(OCCc2ccccc2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +Cc1nn(-c2ccccc2)c(C)c1C=NNC(=O)c1cc(-c2ccccc2)[nH]n1 +C1=C(c2ccc3ccccc3c2)CCN(CCCCc2ccncc2)C1 +Oc1[nH]c(Nc2cccc(CC(F)(F)F)c2)nc2ncnc1-2 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1Nc1ccc2nc[nH]c2c1 +COc1cccc(OC)c1NC(=O)c1ccc(-c2cc(Cl)ccc2Cl)o1 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)NC1C(=O)N2CCOC12 +N#CC(C(=O)Nc1ccc(C(F)(F)F)cn1)=C(O)C1CC1 +Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(C(F)(F)F)n2)c(=O)c2ccccc21 +Cc1ccc(Nc2nnc(SCC3CCCCC3)[nH]2)cc1 +COC(=O)CNC(=O)c1ccc(-n2ncc3c(N)ncnc32)cc1 +Cc1c(Oc2ccc(S(C)(=O)=O)cc2F)ncnc1N1C2CC3CC1CC(C2)N3C(=O)OC1(C)CC1 +CC1CCc2cc(-c3ccc(-n4ccnc4)nn3)ccc2N1C(=O)c1ccc(O)cc1O +CN(C(=O)C(CC(=O)O)NC(=O)CCCCOc1ccc(C(=N)N)cc1)C(Cc1ccc(O)cc1)C(=O)O +O=S(=O)(c1ccc2c(c1)CCNCC2)N1CC(Oc2cccc(Cl)c2)C1 +C=C(c1ccc(S(=O)(=O)c2ccc(OC)cc2)cc1)C1CCN(C2CCN(S(=O)(=O)Cc3ccccc3)CC2)CC1 +COc1cc(CNC2COC(C(c3ccccc3)c3ccccc3)CC2O)ccc1O +CN1CCN(c2ccc(Nc3nc4c(-c5ccc(N(C)S(C)(=O)=O)cc5)cccn4n3)cc2)CC1 +Cn1cnc(Nc2nccc(-c3ccc(N4CCCC4)c(C#N)c3)n2)c1 +COc1cc(C2=C(c3c[nH]c4cccnc34)C(=O)NC2=O)cc(OC)c1OC +O=C1c2c(cc(Cl)cc2C(F)(F)F)C2CNCCN12 +CC1Cn2ncc(C3CCN(S(C)(=O)=O)CC3)c2CN1c1ccnc2[nH]cnc12 +C=CCCCC(=O)OC(C)C1CN(C(=O)CCC=C)C1=O +Cc1nc(C2CCOC2)c2c(N3CCc4cnn(C5CC5)c4C3)ncnn12 +Oc1cc(CC2CCN(CCc3ccc4c(c3)C(O)CCO4)CC2)ccc1Br +C#CCCCN1C(=O)C(C2=NP(=O)(OCC)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)C1C(C)(C)C +Cc1nc(NCc2ccc(C(C)(C)C)cc2)nc(C(F)(F)F)n1 +CN(CCc1ccccn1)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2c(Cl)cc(Cl)cn12 +CCOC1CN(C2CCC(O)(c3ccc4c(c3)OCO4)CC2)CC1NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 +CCNC1CN(CCCO[N+](=O)[O-])S(=O)(=O)c2sc(S(N)(=O)=O)cc21 +CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2cccc(CNC(=O)Cn3ccnc3)c2)n1 +CCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCCCCNCC +CC(C)c1cccc(C(C)C)c1NC(=O)Nc1nc2ccccc2n1-c1c(Cl)cccc1Cl +O=C(NCC1CCOCC1)c1cnc(Nc2cc(Cl)cc(Cl)c2)nc1C(F)(F)F +O=c1cc(C(F)(F)F)c2cc(NCC(F)(F)F)ccc2[nH]1 +COc1cc(Cn2c3ccccc3c(=O)c3cc(NC(=O)CCCCCN)ccc32)cc(OC)c1 +CC#CC(=O)N1CCC(n2cc(C#Cc3cc(OC)cc(OC)c3)c3c(N)ncnc32)C1 +Cc1ccc(NC(=O)C2C3(C)CCC(C3)C2(C)C)cc1S(=O)(=O)N1CCOCC1 +N=C(N)c1cccc(C2Oc3ccccc3N(CCCCCN3CCOCC3)C2=O)c1 +O=C(OCC12CCN(CC1)CC2)c1c[nH]c2ccccc12 +Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(N5CCCC5=O)cc4)c3Cl)cccn2c1Br +c1ccc(CNCc2ccc(CC3CCNCCCOCCCNCC3)cc2)nc1 +Cc1ccc(OC(=O)N(CC(=O)O)Cc2cccc(OCc3nc(-c4cccc(Cl)c4)oc3C)c2)cc1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(Cl)cnc1NCc1c[nH]cn1 +Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3OCC(=O)N(C)C)c2n1 +Cc1nn2c(O)cc(-c3ccc([N+](=O)[O-])cc3)nc2c1-c1ccccc1 +N#CCNC(=O)C1(NC(=O)c2cccc(Br)c2)CCCCC1 +NS(=O)(=O)c1ccc(OCC(c2ccccc2)c2ccccc2)cc1 +Cc1cc(C2CCN(C(=O)C3CC(C)(N(C)C)CC3c3ccc(F)cc3F)CC2)n(-c2cc(Cl)ccc2Cl)n1 +O=C(O)c1cc(=O)c2c(ccc3c(=O)cc(C(=O)O)[nH]c32)[nH]1 +Cc1ccc2c(c1)-c1nc(N)nc(C3CCC(Br)O3)c1C2 +COc1cccc(-c2cc3cc4c(cc3o2)OC(C(C)(C)O)C4)c1 +CN1CCN(c2ccc(Nc3nc4c(-c5ccc(S(=O)(=O)N(C)C)cc5)cccn4n3)cc2)CC1 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+O=C(NC(c1ccc(F)cc1)c1ccc(F)cc1)C1CCC(N2CCOCC2)CC1c1ccccc1F +CN(C)CCC(Oc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cc1)c1ccccc1 +CC(=O)N1CCN(S(=O)(=O)c2ccc(OCc3ccccc3C)cc2)C(C(=O)NO)C1C +CC(C)CN(Cc1ccc(N2CCN(C(=O)C3(O)CC3)CC2)cc1)S(=O)(=O)Cc1ccccc1 +CC1CCCCN1C1(C(=O)N2CC(S(=O)(=O)c3ccccc3Cl)CC2C(=O)NC2(C#N)CC2)CC1 +O=C(O)CCC1(c2cccc(C(F)(F)F)c2)CCCN(C(=O)Nc2ccc(Cl)cc2)C1 +CNC(=O)C1OC(n2cnc3c(NCc4cccc(Cl)c4)ncnc32)C(O)C1O +O=C(C=Cc1ccc(Br)cc1)N1CCN(Cc2cc(F)cc(F)c2)CC1 +CC(Nc1ncc(Cl)c(Nc2cc(C3CC3)[nH]n2)n1)c1ncc(F)cn1 +O=C(Oc1ccc([N+](=O)[O-])cc1)N1CCN(Cc2cccc(Oc3ccccn3)c2)CC1 +Cn1cc(Nc2ncc(C(F)(F)F)c(NC3C4C=CC(C4)C3C(=O)NCCO)n2)cn1 +CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CN(C(=O)Nc2cccc3ccccc23)CCN1Cc1ccccc1 +Oc1cccc(-c2ccc3c(-c4ccccc4)c(O)ccc3c2)c1 +CCOc1cc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(Cl)c3)c2cc1NC(=O)C(F)=CCN(C)C +CNC(=O)c1ccc2c(c1)S(=O)(=O)c1ccc(C(C)O)cc1C2=O +O=C(CCN1CCCCC1)N1CCN(c2ccnc3cc(Cl)ccc23)CCN(c2ccnc3cc(Cl)ccc23)CC1 +CN(C)CCOc1ccc2c3c(oc2c1)C(=O)c1ccccc1C3=O 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+Cc1[nH]c(Cl)c(C)c1-c1ccnc(Nc2ccc(F)cc2)n1 +COc1ccc(C(=O)NCCCCN2CCN(c3nsc4ccccc34)CC2)cc1 +O=c1[nH]nc2c3c([nH]c4cc(F)cc1c43)CCCC2 +CN(C)Cc1cc2nc(-c3cccc(O)c3)nc(N3CCOCC3)c2s1 +CC1=CC2Cc3nc4cc(Cl)ccc4c(NCCCN(C)CCCCNc4c5c(nc6ccccc46)CCCC5)c3C(C1)C2 +CC(C)(O)c1cc2nc(-c3cnc(N)nc3)nc(N3CCOCC3)c2s1 +Oc1cnc(-c2ccc(F)cc2)c(-c2ccc(OCc3ccc4ccccc4n3)cc2)c1 +Cn1cc(-c2cnc(N)c(-c3ccc(C(=O)NCc4cccc(S(C)(=O)=O)c4)c(F)c3)n2)[n+](C)c1 +CNC(=O)C(CC(C)C)N(Cc1ccc(OC)cc1)S(=O)(=O)c1ccc(Cl)cc1 +Cc1ccc(NC(=O)c2ccc(CN3CCN(CCO)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2ccccn12 +Cn1c(-c2cccc(F)c2)nc2c(N)nc(C#CC3(O)CCCCC3)nc21 +CCC(Nc1c(Nc2cc(C)cc(C(=O)N(C)C)c2O)c(=O)c1=O)c1cccs1 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)CC(=O)Nc1cc(NCC)cc(C(F)(F)F)c1 +CN1CCCC(O)(C#Cc2cc3c(cc2F)OCCc2sc(C(N)=O)nc2-3)C1=O +COC(=O)CC(Nc1nc2[nH]c(C)cc(=O)n2n1)c1cccc(Cl)c1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)cc3)nc(C(F)(F)F)c12 +CCCNC(=O)Nc1cccc(-c2ccc(CC(NC(=O)Oc3ccc(OC)cc3)C(=O)O)cc2)c1 +CC(C)(CO)C(=O)Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2Cn2ncnn2)o1 +CCCNc1nccc(N2CCC(Oc3ccc(C(C)C(=O)NCC(F)F)cc3)C2)c1F +COc1ccc(C2CCN(CC3CCC(NC(=O)C=Cc4cc(F)cc(F)c4)C3)CC2)cc1 +Cc1ccc(C)c(OC(CCN2CCC(n3c(O)nc4ccccc43)CC2)C(C)C)c1 +N#Cc1ccccc1-c1cc(F)cc(-n2nnc(-c3ccccn3)n2)c1 +CC1(C)CCCN(CCCCCn2c3ccccc3c3ccccc32)C1 +CCCOc1ccc(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C(F)(F)F)cc1 +COc1ccc(C(C)NCCc2cc(OC)c(NC(=O)Nc3cnc(C#N)cn3)cc2Cl)cc1 +COc1cc2c3c(cc4ccccc4c3c1OC)NC(=O)C2=O +O=C1NC(=O)C(=Cc2ccc(OCCOc3ccccc3Cl)cc2)S1 +COC(=O)c1cc2occc2n1CC(=O)c1cccc(F)c1 +Cc1cc(F)ccc1COc1ccc(S(=O)(=O)NCC(=O)NO)cc1 +Nc1nc2c(-c3cnc4ccccc4c3)nccc2[nH]1 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCC1CCc2n[nH]cc2C1 +CC(C)(C)OC(=O)N1CC=C(c2cn(S(=O)(=O)c3ccccc3)c3ccccc23)CC1 +COc1cc(OCC(O)CNCCN2CCOCC2)c2c(c1)OC1COc3cc(OC)c(OC)cc3C1(O)C2=O +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)N(C)Cc1ccccc1 +O=S(=O)(NCCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1Cl +N=C(N)c1ccc(NC(=O)c2cc3cc4ccccc4cc3cc2O)cc1 +CCCCC(CC1(C(=O)Nc2nnc(CC)s2)CCCC1)C(=O)O +Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccc(Cl)cc3)c2)c1 +COc1ccc(S(=O)(=O)Nc2ccc(C)c(CC(=O)NCc3ccc(C(=N)N)cc3)c2O)cc1OC +Oc1ccc(CSc2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CCN1C2CCC1CC(c1ccnc3c(-c4ccc(C(F)(F)F)c5[nH]ncc45)c(-c4ccncc4)nn13)C2 +CC(O)(C(=O)Nc1ccc(S(=O)(=O)c2cccnc2)cc1)C(F)(F)F +Fc1ccc(CCN2CCN(CC(F)Cc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)cc1 +O=C(CCc1nc(-c2ccc(O)cn2)no1)Nc1ccccc1C(=O)O +CC(CCc1ccc(-c2ccc(Cl)cc2)cc1)(C(=O)NO)S(C)(=O)=O +CNCc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)s2)c1 +NC(=O)C[N+]12CCC(CC1)C(OC(=O)C1(C3=CC=CC3)CCCCCC1)C2 +CCCCOC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCC +CC(C)CN(C)C(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +O=C(O)c1nccc(-c2ccc(F)c(C(F)(F)F)c2)n1 +CC(C)c1cc(Nc2cc(OC3CCN(C)CC3)nc(NCc3cc(C(C)C)no3)n2)[nH]n1 +CC(C#Cc1cnc(Oc2ccc(Oc3ccccc3)cc2)s1)NC(N)=O +NC1(Cc2ccc(Cl)cc2)CCN(c2ncnc3[nH]cnc23)CC1 +CC(C)=CCCC1(C)C=CC(OC(=O)C=C(C)C)C(C)(O)C=CC(=O)C(CCl)=CC1 +CC(=O)OCC12CCC(C)=CC1OC1C(O)C(OC(C)=O)C2(C)C12CO2 +O=C(N1CCOCC1)N1Cc2c(-c3ccc(F)cc3)ncn2-c2ccccc21 +CCCC(=O)OCC1(N(C(=O)CCC)c2ccccc2)CCN(CCc2cccs2)CC1 +CC(C)(C)OCCCn1c(NCc2ccccc2Cl)nc2nc(C(N)=O)ccc21 +N#CC1(NC(=O)Cc2nnc(Cc3nc4c(-c5ccccc5)cccc4s3)o2)CC1 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1CC1CCCCC1 +C=CC(=O)Nc1ccc2ncnc(Nc3ccc(C(C)C)cc3)c2c1 +Oc1ccc(-c2cnc3[nH]cc(-c4ccc5[nH]ccc5c4)c3c2)cc1 +COc1ccc2c(c1)C(=O)N(CC1(c3cc4ncccc4o3)NC(=O)N(COC(=O)C(C)(C)C)C1=O)C2 +Fc1ccc(-c2cc(NCCN3CCCC3)c3ccccc3n2)cc1 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(C(=O)CCCNS(=O)(=O)c2cccc3c(N(C)C)cccc23)CC1 +CC(C)n1cc(C(=O)c2ccnc(NC(=O)Cc3ccccc3Cl)c2)c2cnccc21 +CC(O)(CS(=O)(=O)c1ccc(N=C=S)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CCN(CC)C(=O)c1ccc(N(c2cccc(CNC)c2)C2CCN(Cc3ccccc3)CC2)cc1 +CCCN(CCc1ccccc1)C(=O)c1c(CC)nc2n1CCN2c1c(C)cc(C)cc1C +CCCn1c(=O)c2[nH]c(-c3ccc(OC(C)(C)C(=O)Nc4ccccc4)cc3)cc2n(CCC)c1=O +OC1CCN(c2nccnc2Oc2ccc(Nc3ccccn3)cc2)C1 +N=C(N)c1ccc(CC(NC(=O)CNS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCC2)cc1 +CCCOc1ccccc1-c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)no1 +O=C(NCc1cnccn1)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +O=C(O)COCC1CCC(COC(=O)N(c2ccccc2)c2ccc(C(F)(F)F)cn2)CC1 +Cc1nnc(-c2ccc3c(c2)CN2CCC3(c3ccc(Cl)cc3)CC2)s1 +COC(=O)C1=C(Nc2ccc(Br)cc2)CC(c2ccc(Cl)cc2)N(c2ccc(Br)cc2)C1c1ccc(Cl)cc1 +CCCc1c(OCCCCOc2ccc3c(ccn3CC(=O)O)c2)ccc2c(C(F)(F)F)noc12 +Cn1c(N(Cc2ccc(C(=O)Nc3nnn[nH]3)cc2)C2CCC(C(C)(C)C)CC2)nc2cc(Br)ccc21 +O=C(O)c1ccccc1Oc1ccc(F)cc1NS(=O)(=O)c1ccc(Cl)cc1 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC2CCCCC2)C(=O)CCCO)c1 +O=C(CNC1C2CC3CC(C2)CC1C3)N1CCCC1B(O)O +OC(C#Cc1ccc2cc(-c3n[nH]c4cccnc34)[nH]c2c1)C1CCCC1 +CC(C)N1CCC(NC(=O)c2ccc(OC3CCN(C4CCC4)CC3)cc2Cl)CC1 +Cn1nnc(-c2c(F)cc(Cl)cc2-c2cnc(CNC(=O)N(O)C3CCCC3)c(F)c2)n1 +O=C(Cc1cnc[nH]1)NC(Cc1ccccc1)C(=O)Nc1ccc(Oc2ccc(Cl)cc2)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(N4CCN(c5ccccn5)CC4)nc23)N1 +COC(=O)CCC1N=C(c2ccccc2)c2cc([N+](=O)[O-])ccc2NC1=O +C=CCN1CC(C)N(C(c2cccc(O)c2)c2cccc(C(=O)N(C)CCc3ccccc3)c2)CC1C +C=C1C(=O)OC2CC(C)C3CCC(O)C3(C)C(OC(C)=O)C12 +Cc1nc(S(C)(=O)=O)ccc1Oc1ncnc(OC2CCN(C(=O)C(C)(C)F)CC2)c1F +COc1cc(C(=O)NCc2ccc(Cl)cc2Cl)ccc1-c1cn[nH]c1 +N#Cc1cc(-c2ccnc(Nc3ccc(NC(=O)CN4CCOCC4)nc3)n2)cnc1N1CCCOCC1 +CCCCOc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Cc1ccc(-c2cc(NC(=O)c3ccccc3)on2)cc1 +CC1NC(c2ccnc(C#N)c2)=NC1(c1ccc(F)cc1)c1ccc(F)nc1 +Nc1ccc(-c2cc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CC(C)(O)C1CCC(NC(=O)c2cnc(-n3ccc4cc(F)cnc43)cc2NC2CC2)CC1 +CC(=O)OC(CCCN1CCN(c2ncc(F)cn2)CC1)c1ccc(F)cc1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2ccc(Cl)cc2F)C1 +CCCc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)N(CCC)CCC +CN(C)CCn1c2c3c(n[nH]c(=O)c4cc(F)cc1c34)CN(C(=O)C1CC1)C2 +Nc1nc2sc(CCCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)cc2c(=O)[nH]1 +O=C(NN=Cc1cccs1)c1cc(C23CC4CC(CC(C4)C2)C3)c2ccccc2n1 +CC(C)N(CCNC(=O)C1c2ccc(Oc3ccc(C=O)cc3)cc2CCN1C(=O)OC(C)(C)C)C(C)C +NC(=S)NN=C(c1cccc(Br)c1)c1ccc(F)c(Br)c1 +Cc1cc2ccc(OCc3ccc(CN(C)Cc4ccc(C#N)cc4)cc3)cc2oc1=O +O=C(NC1CCC(CNc2ccccc2)CC1)c1cccc(Cl)c1 +N=C(N)c1ccc(CNC(=O)CNC(=O)C(CO)NS(=O)(=O)Cc2ccccc2)cc1 +CCc1ncnc(-c2ccc(C(=O)NCCN3CCOCC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCOc1ccc(Cc2cc(C34OCC(CO)(O3)C(O)C(O)C4O)ccc2Cl)c(F)c1F +CC(=O)Oc1ccccc1C(=O)Oc1ccc(CCO)cc1 +CC1=C(Sc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)C2C(=O)NC(N)=NC2N1 +CNC(=O)c1cccc2c(Nc3cc(N)cc(CO)c3)c3ccccc3nc12 +Fc1ccc(CC2CCN(CCC#Cc3c[nH]cn3)CC2)cc1 +Cc1c(N(CCCCC(F)(F)F)S(=O)(=O)c2cccc(C#N)c2)sc2ccccc12 +O=C(NC1CNC1)c1cccn2c(=O)c3cc4ccccc4cc3nc12 +O=C(NO)C1C[S+]([O-])CN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +CC(=O)Nc1nc2c(Oc3cc(N4CCN(C(c5ccccc5)c5ccccc5)CC4)ncn3)cccc2s1 +O=C(Nc1ccc(-c2nc3cc(NC(=O)c4ccccc4Cl)ccc3[nH]2)cc1)c1ccccc1 +CNC(=O)C(NC(=O)C(CC(C)C)C(NCc1ccc2ccccc2c1)C(=O)NO)C(C)(C)C +CN1CCN(c2ncc(-c3cc(Cl)cc(Cl)c3Cl)c(N)n2)CC1 +CC(=O)NCC1OC2CC3(C)OC4C=CC5OC6C=CC7OC(C=CC=CC=O)C=CC7OC6CC5OC4CC3OC2CC1O +CC(C)c1cccc(NC(=O)c2cccc(N3CCc4c(cncc4C(=O)O)C3)c2)c1 +Fc1cc(Nc2nc(NCc3ccccc3)c3ccccc3n2)ccc1Cl +CC(C)(C)C(NC(=O)C(CCCc1ccccc1)CC(=O)O)C(=O)NC1CCCCC1 +CCOC(=O)c1c(Cc2cccc(Cl)c2)[nH]c2cc(-c3ccc(-c4ccccc4)cc3)c(O)cc12 +CCc1cccc(N(C)C(=N)Nc2cc(Br)cc(SC)c2Br)c1 +COC(=O)c1cccc(N2CCN(CC(=O)Nc3ccc(-c4nc5cc(C#N)cc(C)c5o4)cc3)CC2)c1 +CC(=O)c1sc(NC(=O)NC2CCN(CC(=O)N(C)C)CC2CN2CCCC(Cc3ccc(F)cc3)C2)nc1C +COc1sc(NC(=O)N2CCN(C(=O)C3CN(C(C)(C)C)CCN3)CC2)nc1C +O=C(O)Cn1nnc(-c2cnc(N3CC4(CCN(c5cc(F)ccc5Cl)CC4)C3)s2)n1 +CC(O)C(NC(=O)N1CCN(c2ccc(C#Cc3ccc(N4CCOCC4)cc3)cc2)CC1)C(=O)NO +CN1CCN(C(=O)c2cc3ccc(Br)cc3[nH]2)CC1 +CCCN(CCN1CCN(C(=O)c2cc3ccccc3o2)CC1)C1CCc2c(O)cccc2C1 +O=C(NC1(CO)CCCC1)c1nn(-c2ccc(F)cc2F)c2c1CC1CC21 +Cc1onc(-c2cccc(F)c2)c1COc1ccc(C(=O)NCC2CC2)cn1 +Cc1cc(-c2cccc(OC(F)(F)F)c2)ccc1NC(=O)C1=C(C(=O)O)CCC1 +COc1cc(-c2ncn(C)c2-c2ccc3c(c2)c(Cl)cn3C)cc(Cl)c1OC +O=S(=O)(NCCOc1ccc2c(c1)C(C1(c3ccc(Cl)cc3)CCC1)NCC2)c1cccnc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCC(Nc3ccc(F)cc3)CC2)c2ccc(Cl)c(Cl)c2)CC1 +CC(C)CCC(=O)NC1CCC(CCN2CCC(c3cccc4c3CCO4)CC2)CC1 +O=C(OCc1ccccc1)c1c(Cl)c2c(c(CCn3cnc4c3NC=NCC4O)c1Cl)CCCC2 +FC(F)(Br)CNC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(CCC(F)(F)F)NC1CCC(CCN2CCC(c3cccc4c3CCO4)CC2)CC1 +O=C(NCc1ccccc1)c1cnc(NCCCn2ccnc2)nc1Nc1ccccc1 +O=C(Nc1ccc(Cl)cc1)c1c(NO)cc(-c2ccccc2)oc1=O +COc1ccc(-c2nn3c(-c4cnc(N5CCN(C)CC5)c(C(F)(F)F)c4)cnc3s2)cc1OC +CC(C)C1(c2cccc(-c3cccc(Cl)c3)c2)NC(=N)N(C)C1=O +CCc1cccc(CCC(O)CCC2C(O)CC(O)C2CCCCCCC(=O)O)c1 +O=C(C1CSCN1C(=O)CC1Cc2ccccc2C1)N1CCCC1 +COc1ccc(-c2ccc(S(=O)(=O)C(CCN3C(=O)c4ccccc4C3=O)C(=O)O)cc2)cc1 +O=C(NCC1(F)CNC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +COC1=CC=C2C3Cc4ccc(O)c5c4C2(CCN3C)C1O5 +Oc1ccc2c(c1)C1c3cc(O)c(O)cc3CCC1NC2 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C(S)c1ccccc1 +O=[N+]([O-])c1c(O)nc2cc(Cl)cc(Cl)c2c1O +O=C(NCCCCN1CCN(c2ccccc2OCCF)CC1)c1ccc(CCF)cc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CCC(C)CC3)c2)[nH]1 +CC(C)(O)Cn1c(=NC(=O)c2ccc(-c3cn[nH]c3)s2)[nH]c2cc(CN3CCCCC3CO)ccc21 +CCN1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 +CCCCNC(=O)c1ccc(OC2CCN(CC3CCCCC3)CC2)c(Cl)c1 +CC(Nc1nccc(N(CC2CCOCC2)C(=O)c2ccc3c(c2)CCO3)n1)c1ccccc1 +Cc1c(C(=O)Nc2ccncc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCC(=O)N1N=C2c3cc(OC)ccc3CCC2C1c1ccc(OC)cc1 +CC(C)CNC(=O)c1ccc(-c2ccccc2C(=O)Nc2ccc(C(=N)N)cc2)c(C(=O)O)c1 +CCN(CC)C1(CNC(=O)N2CCC(c3nc(-c4ccc5ccccc5n4)no3)CC2)CCCC1 +O=C(O)c1[nH]c(=O)[nH]c(=O)c1CCc1nccc2ccccc12 +COc1ccc2c3c1OC1C(=O)CCC4(NC(=O)CC=Cc5ccc(Cl)cc5)C(C2)N(CC2CC2)CCC314 +COC(=O)C1CCCCC1c1ccc(CNc2nccc(C)c2NC(=O)CC#N)cc1 +Cc1ccccc1-c1ccc(CCC(=O)Nc2ccccc2C(=O)O)cc1 +Cc1c(NC(=O)c2ccc(C(C)(C)C)cc2)cccc1-c1ncnc2[nH]c(C3=CCC(N(C)C)CC3)cc12 +COc1ccc(CC=Cc2ccccc2C=CC(=O)NS(=O)(=O)c2cccs2)cc1 +Cc1ccccc1N1CCN(c2ccc(C(=O)NCCCN3CCCC3=O)cc2NC(=O)c2coc(C3CC3)n2)CC1 +CC(C)(C#N)c1cccc(C(=O)Nc2cccc(Oc3ccc4nc(NC(=O)C5CC5)sc4c3C#N)c2)c1Cl +CN1C2CCC1CC(OC(=O)N(Cc1cccs1)c1ccccc1)C2 +CN(C)c1ccc(CC(CS)C(=O)Nc2ccc(S(=O)(=O)O)cc2)cc1 +CC(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1nc3ccc(Cl)cc3s1)c1c(O)ccc(C#N)c12 +CCCOCC1(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CC(c2cccc(C(=N)N)c2)=NO1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(Oc3ccnc4c3[nH]c(=O)n4C)cc2)cc1 +COc1cccc(Nc2nc(-c3cccc(C(N)=O)c3)nc3c2cnn3C)c1 +Fc1ccccc1CSc1nnc(Nc2ccccc2-c2ccccc2)[nH]1 +CC(=O)N1CCN(CC(C)(C)c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCC(C)(C)CC3)c2)CC1 +CON(C1CCC2(C)C(CCC3C2CCC2(C)C(C4=CC(=O)OC4)CCC32O)C1)C1OC(CO)C(N)C(O)C1O +c1ccc2c(NCCOCCOCCNc3c4c(nc5ccccc35)CCCC4)c3c(nc2c1)CCCC3 +CCN1COc2ccc3nc4c(cc3c2C1)Cn1c-4cc2c(c1=O)COC(=O)C2(O)CC +CCc1ccc(-c2ccc(COC(=O)N3CCCC3C(=O)NC(C#N)CC(N)=O)cc2)cc1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(CCCCF)CCO1 +Cc1cnccc1-c1nccnc1OC1CC(Nc2nc3ccccc3s2)C1 +CN1CN(c2ccccc2)C2(CCN(CCCCOc3ccc4c(c3)NC(=O)CC4)CC2)C1=O +O=C(NC1CCN(CCCOc2ccc(F)cc2)CC1)c1ccccc1 +O=C(C1=CC(c2ccc(Br)cc2)CC(OCCCCO)O1)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +CN(C)C1CCN(CCn2nc(Nc3c(Cl)cccc3Cl)c3cnc(Nc4ccccc4)nc32)C1 +CSc1nc2ccc(C(N)=O)cn2c(=N)c1S(=O)(=O)c1ccccc1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCN(C)C2=O +O=C(O)CCn1cc(-c2cnc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +COc1cc(CNCCCN(C)C)ccc1OCc1ccc(F)cc1Cl +O=C(CN1CCCCC1)Nc1cc(CN2CCCCC2)cc(Nc2ccnc3cc(Cl)ccc23)c1 +Clc1ccc(-n2nc(-c3nnc(C4(c5ccccc5)CC4)o3)c(Cn3cncn3)c2-c2ccc(Br)cc2)c(Cl)c1 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+O=c1cc(-c2ccc(OC(F)(F)F)cc2)ccn1-c1ccc2c(cnn2CCN2CCCC2)c1 +CC(Oc1cccc2ccccc12)C(=O)Nc1ccc2oc(-c3ccncc3)nc2c1 +O=C(OCc1ccccc1)N1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +Cc1ccc(F)c(-c2cc(F)cc(C(CC(=O)O)c3ncc(C)s3)c2)c1 +O=C(c1cccc(C(F)(F)F)c1F)N1CCc2c(nnn2-c2ncccn2)C1 +COc1cc(C(=O)c2csc(-c3ccccc3)n2)cc(OC)c1OCCN1C(=O)c2ccccc2C1=O +CC(O)c1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 +NC(=O)Cc1ccc(Nc2cc(=O)[nH]c3ccc(C(c4ccc(Cl)cc4)c4ccc(Cl)cc4)cc23)cc1 +CC(C)(CN1CCOCC1)c1ccc(-n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)cc1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cnn(CCN5CCCC5)c4)nc23)cc1 +CCCCCCCNC(=O)C1Cc2c(sc3ccccc23)CN1 +CC(C)c1csc2ncnc(N3C4CCC3CC(COCCN3CCCC3)C4)c12 +NS(=O)(=O)c1ccc(C(=O)N2CCc3cc(O)ccc3C2c2ccccc2)cc1 +O=c1[nH]c(=S)ccn1C1OC(COP(=O)(O)OP(=O)(O)C(F)(F)P(=O)(O)O)C(O)C1O +O=C(NO)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +O=C(NC(Cc1ccccc1)C(=O)NC(Cc1ccc2ccccc2c1)C(=O)N1CCCC1B(O)O)c1cnccn1 +COc1cccc(OC)c1-c1cc(C(=O)NC(CC(C)C)C(=O)O)nn1-c1ccnc2cc(Cl)ccc12 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+COc1nc(-c2ccc3c(c2)S(=O)(=O)c2ccccc2C3=O)no1 +COc1cc(N2C(=O)c3ccc(F)cc3C2=O)ccc1N(C)C +COC(Cc1ccc(NC(=O)CCCCC2CCSS2)cc1)C(=O)O +COc1cc(C=Cc2ccc3c(c2)oc(=O)n3C)cc(OC)c1OC +COc1ccc(C2CN(C)Cc3cc(OCCCN4CCN(C(=O)c5ccncc5)CC4)ccc32)cc1 +CCCCOc1ccc(S(=O)(=O)C2(C(=O)NO)CCN(Cc3ccc(Cl)c(Cl)c3)CC2)cc1 +CCc1nn(Cc2cc(C)n(C)n2)c2cccc(NC(=O)c3cnc4cc(-c5cnn(C)c5)ccn34)c12 +CCOc1c(C)cc(SC)cc1CNCCCNc1cc(O)c2ccccc2n1 +CC(C)CC1C(=O)NC(C(=O)Nc2ccccc2)CCCCNC(=O)OCCCC1C(=O)NO +CNS(=O)(=O)c1ccc(N2CCOCC2)c(Nc2ncnc3[nH]c(-c4cccc(C(F)(F)F)c4)cc23)c1 +CC(C)(C)c1ccc(CNC(=O)c2ccc(NC(=O)c3cccc(CN4C(=O)OCC4Cc4ccccc4)c3)cc2)cc1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc4c(c3)NCCNC4=O)nc2n1 +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc2c(c1)CN(C(CCC(=O)O)C(=O)O)C2=O +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3(CC3)CN(Cc3ccc(F)cc3)C1=O)N2 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cccc(S(=O)(=O)NCCCC(=O)O)c2)c1 +O=C(Nc1nc(-c2ccccn2)nc2ccccc12)c1ccccc1 +COc1ccc(C=Cc2cc(OC)cc(OC)c2C=CC(=O)NCCCCl)cc1 +CC(C)NC(=O)c1cccc(-c2ccc3c(C=O)c(O)ccc3c2)n1 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+O=C(CNC(=O)c1cccn(Cc2ccc(F)c(F)c2)c1=O)Nc1ccc2c(c1)C(=Cc1cnc[nH]1)C(=O)N2 +Cc1cccc(NC(=O)c2cccnc2SCc2ccncc2)c1 +CC(C)COc1ccc(C(NC(=O)C(C)c2ccccc2)C2CCCN2)cc1 +CCCCCCCCCCCCOc1ccc(COc2cccc(C(=O)O)c2)[n+]([O-])c1C=CC(=O)O +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1ccnc(-n2cccn2)c1 +CS(=O)(=O)c1ccc(-c2cnc(N)c(-c3ccc4nonc4c3)c2)cc1 +CC(C(=O)NCC(COC(=O)C(C)(C)C)Cc1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(Cl)c1 +NC(=O)c1cccc2[nH]c(-c3ccc(-n4ccc(CN5CCCCC5)c4)cc3)nc12 +COc1ccc(C(=O)NN=C(C)C(=NNc2ccc(S(N)(=O)=O)cc2)N2CCCCC2)cc1 +COc1cccc(N(C)C(=N)Nc2cccc3ccccc23)c1 +Cc1cn(C2CC(F)C(COCP(=O)(O)O)O2)c(=O)[nH]c1=O +O=C(NCc1ccc(Cl)cc1Cl)N1CCC(Cc2ccccn2)CC1 +O=c1[nH]c(=O)c2cc(-c3n[nH]cc3CN3C4CCC3CN(c3ccc(C(F)(F)F)cn3)C4)ccc2o1 +CC(=O)NC1CC2CCC(C1)N2CCOc1ccc(Oc2nc3ncccc3s2)cc1 +CCc1c(C)[nH]c(=O)c(N(CC)CC)c1Cc1cc(C)cc(C)c1 +O=C(Nc1ccc(C(=O)N2CCCc3c(Cl)[nH]c4cccc2c34)cc1)c1ccccc1-c1ccccc1 +Nc1cnc(-c2ccc(C3CCC3)c(OCC(O)CNc3ccn[nH]3)c2F)cn1 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(Cc3ccc(S(N)(=O)=O)cc3Cl)CC2)n1 +COc1cc(-c2cc3ncccc3c(OCC3CNC(=O)C3)n2)ccc1OC1CCS(=O)(=O)CC1 +N=C(N)SCc1cccc2c1sc1c(CSC(=N)N)cccc12 +COc1cc2[nH]c(C)c(-c3ccncc3)c(=O)c2cc1Cl +Nc1nccn2c(-c3ccc(OCCN4CCOCC4)cc3)nc(-c3ccc(Oc4ccccc4)cc3)c12 +Nc1c(S(=O)(=O)O)cc(Nc2ccc(O)cc2)c2c1C(=O)c1ccccc1C2=O +N#Cc1ccc(-n2nc(C(=O)N3CCCC(N)C3)cc2OCC(=O)N2CCOCC2)cc1 +CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(CO)c1 +Cc1ccc(NC(=O)c2ccnc(N3CCCC3)c2)cc1-c1ccc2c(N)noc2c1 +COc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CN(c3ccc(F)cc3)C2=O)cc1 +COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cn(CCN3CCN(c4ccccn4)CC3)c2c1 +O=C(O)C=Cc1cn(Cc2ccccc2F)c2ccccc12 +CC(C)[S+]([O-])c1ccc2cc(NC(=O)C3CC3)ncc2c1 +COC(=O)C1CN(C(=O)c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)C1 +CN(c1ncnc2ccccc12)C1CCc2c(c3cc(F)ccc3n2CC(=O)O)C1 +Cc1nc(CC(C)C)cc(-c2nc(-c3cc(F)c(OC4CCC(=O)N(C)C4)cc3Cl)no2)n1 +NC(COc1cncc(-c2ccc3cnccc3c2)c1)Cc1ccc2ccccc2c1 +COc1ccc2c(c1O)CCCC=C2c1cc(OC)c(OC)c(OC)c1 +COc1cncc(-c2cncc(-c3ccc(Oc4ccccc4)cc3)n2)c1 +COC1CCC2(CC1)Cc1ccc(CCCC(C)C)cc1C21N=C(N)N(C)C1=O +O=C(O)CC(O)CC(O)COc1c(Cl)cc(Cl)cc1C(F)(F)C1CCCCC1 +COc1ccccc1N1CCN(CCCCCCCn2ncc(N3CCN(C(=O)c4ccco4)CC3)c(Cl)c2=O)CC1 +O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)C=Cc1ccccc1 +COc1ccnc2c1nc(CCn1c(=O)n(C)c3cccnc31)n2-c1ccccc1 +CC12CC3CC(C)(C1)CC(NCC(=O)N1CCCC1C#N)(C3)C2 +Nc1ccc2nc(-c3ccc(C4=NCCN4)cc3)sc2c1 +CCC(O)(CC)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)OC(C)(C)C)CC1 +Nc1ccc2c(c1)NC(=O)C2=C1Nc2ccccc2C1=NO +COc1cc2nccc(Oc3ccc(NC(=O)NC(=O)c4ccccc4)nc3)c2cc1OC +Cc1ccc(C(=O)N2CC(F)(c3ccc(C#N)cc3)C2)cc1-c1[nH]c(C2(C)CCOCC2)nc1Cl +O=C(NC(=O)c1ccccc1)Nc1nc2ccccc2n2c(=O)n(-c3ccccc3)nc12 +CC(C)(C)OC(=O)NN(CCC1C=CCC1)c1nc(C#N)ncc1Br +CCCCCCSCC(NC(=O)CCC(N)C(=O)O)C(=O)NC(C(=O)O)c1ccccc1 +O=C(Nc1ccc(Cl)c(Cl)c1)Nc1cccc2cnccc12 +CC(=O)c1ccc2c(c1)Cc1cc3c(cc1-2)C(C)=CC(C)(C)N3 +CC1(O)CCCN(S(=O)(=O)c2ccc(OCc3cnccn3)cc2)C1C(=O)NO +COc1cc2ncc3c(c(-c4ccc(C#N)cc4F)nn3C)c2cc1OC(C(N)=O)c1ccc(F)cc1 +COc1ccc(C2=NN(C(=O)c3ccc(C)nc3)C(c3ccc(Cl)cc3)C2)cc1 +COc1cccc(-c2cc([N+](=O)[O-])cc3cc(C(O)(c4ccc(C#N)cc4)c4cncn4C)oc23)c1 +COc1ccc(CN2CCN(Cc3ccccc3)C(CCO)C2)cc1 +Cc1cccc(NC(=O)c2cccc3oc(=O)[nH]c23)n1 +Nc1nc2c(s1)CCC2C(=O)Nc1ccc(CC2CCC(C(O)c3ccccc3)N2)cc1 +COC(=O)c1cccc(-c2ccc(NCc3cncn3Cc3ccc(C#N)cc3)cc2-c2ccccc2)c1 +Cn1cncc1C(O)(c1ccc(Cl)cc1)c1cc2c3c(c1)c(-c1cccc(Cl)c1)cc(=O)n3CCO2 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccc(C#N)cc3)CC2)n1 +CN1CCN(C(=O)C(COCc2ccccc2)NC(=O)c2cccnc2Oc2c(Cl)cccc2Cl)CC1 +COc1ccc(C(=O)Nc2cccnc2NCC2CCN(c3ccncc3)CC2)cc1 +COc1ncccc1-c1nccnc1C1CN(c2ccc3ccccc3n2)C1 +Cc1ccc(N2CCC(N)CC2)c(NC(=O)c2nc(-c3ncccc3C(F)(F)F)cnc2N)n1 +CN(C)CCN1C(=O)c2ccc(S(C)(=O)=O)c3cc4ccccc4c(c23)C1=O +CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C(CC(C)C)NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O +COc1cc(CNCC2CCN(CCCCCC(c3ccc(F)cc3)c3ccc(F)cc3)C2)cc(OC)c1OC +CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)cc2Cl)c(C#N)c1=O +Cc1c(C(=O)N2C3CCC2c2nnc(-c4ccccn4)n2C3)cccc1C(F)(F)F +O=C(NCCc1ccc(Cl)cc1)C1CCCN(c2ncc(F)cn2)C1 +O=C(c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1N1CCN(CCN2CCCC2)C(=O)C1)C1CC1 +O=C1C(=O)N(Cc2ccc([N+](=O)[O-])cc2)c2c(Br)cc(Br)cc21 +COc1cc(C(=O)Oc2cccc3c2C(=O)C=C(N2CC2)C3=O)cc(OC)c1OC +CNC(=O)COc1ccc(-c2cc3c(C(=O)O)c[nH]c3cc2Cl)cc1 +CCCn1c(=O)[nH]c2[nH]c(-c3ccccc3)nc2c1=O +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)OC(C)(C)C)sc2c1 +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C(F)(F)F +COCc1ccn2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c12 +CC12CC(c3ccccc3)CC(C1)N(CCN1CCN(c3cccc(Cl)c3)C1=O)C2 +Cc1cc(CN2CCN(C(C)C)CC2)cnc1-c1ccc(C(=O)Nc2ccccc2N)cc1 +CC(C)OC(=O)C1=CCCCC1S(=O)(=O)Cc1ccc(F)cc1Cl +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1cccc(C)n1)CC2 +CC(C#Cc1ccc2[nH]c(O)nc2c1)N1CCC(Cc2ccc(F)cc2)CC1 +CCOc1ccc(S(=O)(=O)Nc2cc(CC(=O)O)c(NS(=O)(=O)c3ccc(OCC)cc3)c3ccccc23)cc1 +CN(C)CCNC(=O)c1cccc2nc3ccc(Cl)cc3nc12 +O=C(O)C(O)=CC(=O)c1cccc(Cc2ccccc2)c1 +Cc1cc(C#N)cc2nc(-c3ccc(NC(=O)CC4CCN(C(=O)OC(C)(C)C)CC4)cc3)oc12 +O=S(=O)(c1cccc(Cl)c1)c1cn(C2CCNC2)c2ccccc12 +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)NCC(=O)O +CCOc1ccc(Cc2cc(C3OC([S+](C)[O-])C(O)C(O)C3O)c3c(c2Cl)CC(C)O3)cc1 +Cc1[nH]c2c(c1C(=O)N1CCOCC1)CCCC2=C1C(=O)Nc2ccc(F)cc21 +Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1nc2c([nH]1)CN(C)CC2 +CN(C)C(=S)NN=C(c1ccc(C(C)(C)C)cc1)c1ccccn1 +O=C(c1ccc2[nH]c(=O)[nH]c2c1)N1CCCC2c3ccccc3CCC21 +N#Cc1ccc(N2CCc3c(-n4ccc(-c5nccs5)n4)ccnc32)c(OC(F)(F)F)c1 +FC(F)(F)c1ccc(Nc2nc(NC3CC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +O=C(Nc1cc(-c2ccccc2)nn1-c1ccccc1)c1ccc(Cl)c(Cl)c1 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc(O)cc1 +CC(=O)N1CCN(C(=O)C=Cc2ccc(Sc3ccc4cc[nH]c4c3)c(Cl)c2)CC1 +Cn1cc(C2CCC(CCN3CCN(c4ccccn4)CC3)CC2)c2ccccc21 +NC1=NC2(CCO1)c1cc(NC(=O)c3ccc(Cl)cc3F)ccc1Oc1ncc(Br)cc12 +COc1cc2c(cc1OCCCN1CCN(CCN3C(=O)c4cccc5cccc(c45)C3=O)CC1)N=CC1CCCN1C2=O +CC(NC(=O)C1CC1)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3)C2)cc1 +O=C(Nc1ccc(-c2nc(-c3ccc(Cl)cc3)cs2)cc1)C1CCN(S(=O)(=O)c2cccs2)CC1 +CN(C)CCCNC(=O)c1nc(-c2ccc(Cl)c(O)c2)c(-c2ccncc2)[nH]1 +CCC#CCOc1cc(NC(=O)NC(C)c2ccccc2)ccc1OC +CNCC(=O)Nc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O +COc1ccc(CCC(C)(C)O)cc1-c1[nH]nc2nc(Nc3ccc(F)cc3F)ncc12 +COc1ccc2c(c1)c(NC(=O)N1CC(F)CC1C(=O)Nc1cccc(OC(F)(F)F)c1F)cn2C(N)=O +O=C1c2c(cccc2OCC(O)CN2CCCCC2)CC1Cc1ccccc1 +CC1C(=O)N(C(C)(C)C)CCCN1C(=O)CC(N)Cc1cc(F)c(F)cc1F +COC1C(O)CCC2(C)C3CCC4(C)C(=O)CCC4C3CCC12 +CC1CCC(Oc2ccnc3c(F)cccc23)CN1C(=O)c1ccccc1-c1ccccn1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3cc(Cl)ccc3F)n[nH]c2C1(C)C +Cc1ncnc(-c2ccc(C(=O)N(C)C)c(F)c2)c1C#Cc1ccc(N)nc1 +CC(C)Cn1ncc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)c1-c1ccncc1 +CC(Oc1cc(C(=O)NC2(CC(N)=O)CS(=O)(=O)C2)ncc1C1(F)COC1)C(F)(F)F +O=C1c2ccc(F)cc2NC(c2ccccc2F)N1C1CCN(CCCn2ccnc2-c2ccccc2)CC1 +Clc1ccc(-c2c(-c3ccc(Cl)cc3Cl)nnn2Cc2ccccc2)cc1 +CC(C)(C)C(=O)C1=C(O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1cccc[n+]1[O-] +COc1ncc(N2CCc3ncnc(OC4CCN(C(=O)c5cnccn5)C4)c3C2)cc1C(F)(F)F +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1NCCC2c1ccncc1 +O=C(NC1CC1)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 +Cn1cc(Cc2cn(CCCC(=O)N3CCN(c4ccc(C(F)(F)F)cc4)CC3)c(SCc3ccc(F)cc3)nc2=O)cn1 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+Cc1cccc(-c2nc(-c3ccccc3F)[nH]c2-c2ccncc2)c1 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCc1ccccc1 +CCN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(C#Cc4cnccn4)c3)cc2C(F)(F)F)CC1 +COc1cc(Cc2ccc3c(-c4cnn(C)c4)cc(C(N)=O)nc3c2F)cc(C)n1 +CN(Cc1cc(F)cc(F)c1F)C(=O)C1(C)CCCCC1 +CC(=O)c1cc(-c2ccc(O)c(F)c2)nc2ccc(O)cc12 +CC1(O)CC2CCC1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C2(C)C +CC1=NC(C)=C(C(=O)O)C(c2cccc(Cl)c2)C1=C(O)OCC=CC1CCCCC1 +CC(C)Nc1nc2cnccc2nc1N1CCC(Oc2ccc(F)cc2F)CC1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(Nc4ccc(F)cc4F)nc23)N1 +CC(=O)Nc1cccc(Nc2nc3ccccc3n2-c2nc(C)nc(N)n2)c1 +CN(C)CC1CCN(c2c([S+](C)[O-])cnc3ccc(-c4ccc(O)c(Cl)c4)cc23)CC1 +N=C(N)SCCOC1CCC(C2CCC(O)(CC(=O)O)CC2)CC1 +CCN1CC(C)(C)Oc2nc(N3C4CCC3COC4)nc(-c3ccc(NC(=O)OCCO)cc3)c2C1=O +CC(C(=O)OC1C[N+]2(CC(=O)Nc3ccon3)CCC1CC2)(c1ccccc1)N1CCCCC1 +CSc1nn2cc(-c3nc4c(OC(C)C)cccc4o3)nc2s1 +COC(=O)C1=C(C)NC(N2CCOCC2)=NC1c1ccc(F)cc1Cl +CNC(=O)Nc1ccc(OC)c(NC(=O)NC(=O)c2cc(F)c(F)cc2Cl)c1 +NC(=O)N(O)CCC#Cc1ccc(CN2CCN(C(c3ccccc3)c3ccc(Cl)cc3)CC2)o1 +CC(NC(=O)c1c[nH]c2ncc(C3CC3)nc12)C1CCCCC1 +CNc1ncnn2c(C)nc(-c3cnn(C)c3-c3ccc(C(F)(F)F)cc3)c12 +CN(C)C(=O)Cn1cc(-c2cnc(NC(=O)C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)nn1 +CCCCCC(O)C=CC1CC(F)(F)C(=O)N1CCCCCCC(=O)O +Cc1[nH]nc(-c2cc(Cl)c(O)cc2O)c1-c1ccc2c(c1)OCCO2 +CCCOc1cccc2c1CC(C(=O)Nc1ccc(N(CC)CC)cc1)CC2 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1NS(C)(=O)=O +COc1ccc2nc(NCCCN3CCN(CCCNc4nc5ccc(OC)cc5n5cccc45)CC3)c3cccn3c2c1 +CN(C)C(=O)C(c1ccc(-c2ccc(F)cc2)cc1)C(N)C(=O)N1CC(F)(F)C1 +Cc1nc(N2CCCC2)nc2ccc(NC(=O)COc3ccc(C(F)(F)F)cc3)cc12 +O=C(C=Cc1ccc(Br)cc1)N1CCN(C(=O)c2cccc(B(O)O)c2)CC1 +CC(C)CN(NC(=O)c1ccnn1-c1ccccc1)c1nc(C#N)ncc1Cl +CC(=O)NC(CCCCNC(=O)C1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C)C(=O)NCc1ccccc1 +c1ccc(-c2nnc(C3CCN(Cc4ccc(-c5nnc6n5-c5cccnc5Nc5ccccc5-6)cc4)CC3)[nH]2)nc1 +COc1ccccc1N1CCN(CCCNc2ncc(C#N)cc2C(=O)N(C)C)CC1 +COc1cccc(-c2cccc(C3(c4ccccc4)NC(=N)N(C)C3=O)c2)c1 +Cc1cccc(C)c1CC(NC(=O)C(CCCN=C(N)N)NC(=O)C(N)Cc1ccc(O)cc1)C(=O)NCCC(N)=O +O=C(CCc1ccccc1)Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1 +Cc1ccc(NC(=O)c2occc2C)cc1-c1nc2ncccc2o1 +CN1CCN(CC(NC(=O)CC2CNC(=O)c3cc(-c4cc(Cl)ccc4F)cn32)C2CCCCC2)CC1 +Cc1nc(N)sc1CCCNC(N)=NC(=O)CCCCCCCC(=O)N=C(N)NCCCc1sc(N)nc1C +CC(=O)OC1CCC2(C)C(CCC3(C)C2Cc2cc4ccccc4n23)C1(C)C +CCc1nc(N)ccc1C#Cc1c(-c2ccc(C(=O)N3CCN(C)CC3)c(F)c2)ccnc1C +CCCN1CCC2CC3=Nc4ccccc4C3(CC)C3CCCC1C23 +[BH4]P(=O)(OCC1OC(n2cnc3c(N)nc(SC)nc32)C(O)C1O)OP(=O)(O)O +CC(C)(N)CC1CCN(C(=O)C(O)(c2ccccc2)C2CCC(F)(F)C2)CC1 +O=C(Cc1ccccc1F)Nc1onc(-c2ccc(F)cc2)c1-c1ccncn1 +c1ccc2nc(N3CCC(Oc4nccnc4N4CC5(COC5)C4)CC3)ccc2c1 +O=C(C1CCNC1)N1CCC(NS(=O)(=O)c2cc(S(=O)(=O)c3ccccc3)ccc2C(F)(F)F)CC1 +O=C(Nc1ccccc1C(=O)Nc1ccc2c(C(F)(F)F)cc(=O)oc2c1)c1ccccc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NN4CCOCC4)nc23)N1 +COCCOc1cncc(-c2cc3c(ccc4c5c([nH]c43)CCNC5=O)cn2)c1 +CN(C)c1ccc(CNC(=O)C(CSCC2CCCCC2)NC(=O)C2CSCN2C(=O)OC(C)(C)C)cc1 +Cc1cc(Cc2cccc(-c3ccccc3)c2)n(O)c(=O)c1 +Cn1nnc(-c2cccc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)c2)n1 +CN(C)c1nc(N)nc(-c2sc(NC(=O)c3ccco3)nc2-c2ccccc2)n1 +CCC(CC)c1ccc(Cl)c2nc(Oc3c(C)cc(C#N)cc3Cl)n(C)c12 +Nc1ncn(Cc2ccc(CCCCc3ccc(C[n+]4ccc(N5CCCC5)cc4)cc3)cc2)c2ncnc1-2 +N#Cc1ccc2cc1Oc1ccc3cccc(c3c1)C(=O)NCCNCc1cncn1C2 +Cc1ccc(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1F +Cc1cccc(CNc2cc(N3CCOCC3)cc(CSc3nc(CF)c(C)s3)n2)n1 +CC(=O)Nc1ccc(-c2ccc(NC(=O)Nc3cccc(C)c3)cc2)c2c1C(=O)NC2 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2ccc(C(C)C)n2)n1 +N#Cc1ccc2nc(Nc3cc(Cc4ccccc4)nc(NC4CCC(O)CC4)n3)sc2c1 +N#Cc1ccc(N2CC3(CN4CCC3CC4)OC2=O)s1 +Cc1c(CN(C)C(=O)C=Cc2cnc3c(c2)CNC(=O)CN3)oc2ccccc12 +OC(c1cnc(N2CCN(c3cccc(Cl)c3)CC2)s1)(C(F)(F)F)C(F)(F)F +Cn1cnc(S(=O)(=O)N(CCN(Cc2cncn2C)c2ccc(C#N)cc2)Cc2ccncc2)c1 +CC1=NC2(CCN(c3c(Cl)cncc3-c3ccc4c(c3)CS(=O)(=O)N4C)CC2)C(=O)N1 +Cc1nnc(CN(C(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)C(C)(C)C)o1 +NC(=NO)c1ccc(CN(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCCC2)cc1 +CCOC(=O)C1=C(C)N=C(SCCC(=O)O)NC1c1ccccc1OC +O=C(O)c1ccc(N2C(=O)C3ON(c4ccccc4)C(c4ccccc4)C3C2=O)cc1 +Cn1c(=O)[nH]c2ccc(-c3ccccc3Cl)c(CN)c21 +O=C1NC(=O)c2c1c1c3ccccc3n3c1c1c2c2ccccc2n1CC(O)CCC3 +Cn1nccc1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCSCC1 +Nc1nc(NCCNc2ncc(-c3ncc[nH]3)c(-c3ccc(F)cc3F)n2)ccc1[N+](=O)[O-] +O=c1cc(N2CCOCC2)nc(Cc2nc3cccc(F)c3o2)[nH]1 +COc1ccc(C(=O)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1 +COCCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccccc2)CC3C)n1 +Cc1c(C(C)c2c(Cl)cccc2Cl)nc(N(C)Cc2ccc([N+](=O)[O-])cc2)[nH]c1=O +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cccc(C(F)(F)F)c2)cc1 +O=C(CC1CN(Cc2ccccc2)CCN1c1ccnc(-n2ccnc2)n1)NCc1ccc2c(c1)OCO2 +CC(C)(CO)C1CC(Sc2ccccc2)c2cc([N+](=O)[O-])ccc2N1 +CCC(C)C(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccc(COC)cc2)cc1 +Cc1ccc(-c2ccc(OCCN(C)CC(=O)O)c(C(=O)c3cccs3)c2)cc1 +CCC1=NN(C(=O)c2ccccc2O)C(O)(c2ccccc2)C1 +NC(=O)C(=O)N1CC2CC(CN(C(=O)CN3CCCC(NS(=O)(=O)c4ccc5cc(Cl)ccc5c4)C3=O)C2)C1 +CCC(=O)N(c1ccccc1)C1CCN(C(=O)C(N)C(C)c2c(C)cc(O)cc2C)CC1 +CN1CCN(C(=O)CNc2ccnc3cc(Cl)ccc23)CC1 +CC1(O)CCC2C(CCC3C2CCC2(C)C(C(=O)Cn4cccn4)CCC32)C1 +CCCC(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1 +CN1CCN(CC(NC(=O)CC2CNC(=O)c3cc(-c4cccc(Cl)c4)cn32)C(C)(C)C)CC1 +COC(=O)Nc1nc2cc(Oc3cccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)c3)ccc2[nH]1 +CC(C)n1cnc2c(NCc3ccc(-c4ccccn4)s3)nc(NC3CCC(N)CC3)nc21 +COCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(SC)cc1 +N#Cc1ncc(C(=O)NCCc2ccccc2)c(NCC2CCC(F)(F)CC2)n1 +COc1cnc2c(Nc3ccc(F)c(C4(CF)CC(C(F)(F)F)OC(N)=N4)c3)nccc2c1 +CN1CCN(NCc2ccc3c(c2)-c2nc(N)nc(-c4ccc(F)cc4)c2C3=O)CC1 +O=C(NCc1ccc(Cl)c(Cl)c1)N1CCCC1CN1CCCC1 +COc1ccccc1CNC(=O)c1c(-c2ccccc2C)c2ccccc2c(=O)n1C +NCCCCCCNC(=O)N=C(N)NCCCC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CN(C(C)=O)C3)cc12 +COc1ccc2c(ccn2S(=O)(=O)c2cccc(C(=O)Nc3ccc(C)cc3C(=O)O)c2)c1C +Cc1cccc(CNC2=NC(=Cc3c[nH]c4ncccc34)C(=O)N2)c1 +Cc1noc(C)c1COC(=O)c1ccc(-c2nc3ccccc3s2)s1 +CCN1CCCC1C(=O)NC12CC3CC(F)(CC(C1)c1ccccc13)C2 +CCC1(OC(=O)C[n+]2cccc(C(C)=O)c2)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 +N#CCCN1C(=O)C(Cc2c[nH]c3ccccc23)N=C(c2ccccc2F)c2ccccc21 +Nc1c(S(=O)(=O)O)cc(Nc2ccc3cc4ccccc4cc3c2)c2c1C(=O)c1ccccc1C2=O +Cc1ccnc(NC(=S)N2CCN(c3cccc(C(F)(F)F)c3)CC2)c1 +Oc1ccc(-c2c(Cl)c3cc(O)ccc3n2Cc2ccc(OCCN3CCCCCC3)cc2)cc1 +N=C(N)c1ccc(-c2ncc(-c3ccc(C(=N)N)nc3)cn2)cc1 +CN(C)CCCCn1c(CCc2ccccc2)nc2cc(C=CC(=O)NO)ccc21 +O=c1[nH]c(CCCN2CCC(c3ccc(F)cc3)CC2)nc2c(Cl)cccc12 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1 +O=C1NCCN1c1ccc(S(=O)(=O)Oc2ccc(Cl)cc2)cc1 +O=C(c1c(Oc2cc(F)ccc2F)n(-c2ccccc2)c2cccnc12)N1CCNCC1 +CCN(C(=O)OCc1ccccc1)C1CCN(C(C)CC(NC(=O)C2CCC2)c2ccccc2)CC1 +O=C(CCCCCCCCc1ccc(O)cc1)c1c(O)cccc1O +CC(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc21 +Cc1ccc(-c2noc(C3CC4(C3)OCCCO4)n2)cc1NC(=O)c1cnc2ccccn12 +CCOC(=O)C1(c2ccccc2)N=C(c2ccc(OC)cc2)N(Cc2ccccc2)C1c1ccc(NC(=N)N)cc1 +CN(C)c1ccc(-c2cc(=O)c3ccc(OCC(=O)NCCCNc4c5c(nc6ccccc46)CCCC5)cc3o2)cc1 +O=[N+]([O-])c1cnc(Sc2nnc(O)n2-c2ccc(OC(F)(F)F)cc2)s1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3ccc(F)nc3)cc2s1)S(=O)(=O)CCC(F)(F)F +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NCc1cc(Cl)ccc1F 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+O=C(NCc1cn(-c2ccccc2)nc1-c1ccccc1)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1 +C=C(c1cc(OC)c(OC)c(OC)c1)c1ccc2c(c1)c(C#N)cn2C +Cc1ccnc(NC(c2cccc(Cl)c2Cl)c2ccc3cccnc3c2O)c1 +CNC(=O)C12CC1C(n1cnc3c(NC4CCC4)nc(N=[N+]=[N-])nc31)C(O)C2O +CCCc1ccc(C(=O)Nc2ccccc2-c2nnn(-c3ccc(SC)cc3)n2)cc1 +O=C(CC(NC(=O)c1ccc(-c2ccccc2CN2CCOCC2)cc1)C(=O)N1CCCCC1)Nc1ccc(Cl)cn1 +CC(c1ccc(F)cc1)N1CCC(N2CCC(c3ccc(O)cc3)C(F)(F)C2)C1=O +CC(=O)N1CCc2ccc(N(C(=O)C=Cc3cccc([N+](=O)[O-])c3)C3CCN(CCC4CCCC4)CC3)cc21 +COc1cc(Cl)ccc1CC(C)C(=O)N1CCN(c2c(F)cccc2C(N)C(C)C)CC1 +COc1cc(NC(=S)n2cc(-c3ccc4ncnn4c3)c(-c3cccc(C)n3)n2)cc(OC)c1 +CCCCCCCOc1ccc(C(=O)Nc2cccc3c(=O)cc(-c4nn[nH]n4)oc23)cc1 +CCOC(=O)CCCCOc1cc(-c2ccccc2)nc2cccc(CC)c12 +CCc1cc2c(C(=O)Nc3c(Cl)c[n+]([O-])cc3Cl)cnc(OC(F)F)c2o1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(CCNC(=O)c4ccccc4)c3)s2)nn1 +Cc1ccc(NC(=O)Nc2ccc(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)cc2)cc1 +CCN1C(C(=O)NC(Cc2ccccc2)C(=O)C(=O)NCCOC)Cc2cc3c(cc2S1(=O)=O)OCCO3 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+CCC(=O)c1ccc2c(c1)sc(=O)n2CCN1CCCC1 +CC(C)Cn1c(=O)n(C)c(=O)c2c(C(=O)N3CC=CC3)c(Cc3ccccc3C(F)(F)F)sc21 +CC#CCC(C)C(O)C=CC1C(O)CC2(CCCCCN=[N+]=[N-])CC(=CCCCC(=O)O)CC12 +COc1cc(OC)cc(N(CC#Cc2cc(C#N)ccn2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C(OC(C(F)(F)F)C(F)(F)F)N1CC(c2ccn(-c3ccccc3)n2)C1 +CC(NC(=O)c1nc(N2CCC(F)(F)CC2)c2cnccn12)C(C)(C)C +COc1cc(O)cc(CCc2cccc(O)c2)c1-c1c(OC)cc(O)c2c1CCc1cc(O)ccc1-2 +Cc1cc(CC#N)cc(-c2c(O)nc3cc(Cl)c([N+](=O)[O-])cc3c2OCCC2CCCCN2)c1 +CCNC(=NS(=O)(=O)c1ccc(N)cc1)N1CC2(C=N1)CCNCC2 +COc1nc2c(cc1NCc1ccc(F)cc1)c(=O)c(C(=O)O)cn2C(CO)C(C)C +Cn1c(=O)c2c(nc3nc(NCCCN4CCN(c5cccc(Cl)c5)CC4)ccn32)n(C)c1=O +COCC(NC(=O)Nc1cc2[nH]nc(OC3CCOC3)c2cn1)c1ccccc1 +O=C(NO)c1ccc2c(c1)nc(CCc1ccccc1)n2CCCO +CC(=O)c1cccc2c1CCN1C(=O)CN=C(n3cnc(C4CCC4)c3)C=C21 +N#Cc1ccc(C(=O)Nc2ccc(Cl)c(-c3nc4ccccc4[nH]3)c2)cc1 +CCCCCCCCCCC(CC)(CC)C(=O)Nc1c(OC)cc(OC)cc1OC +Cc1cc(-c2nc3c(cnc4cccc(Cl)c43)[nH]2)on1 +COC(=O)C1=C(c2ccc(Cl)c(Cl)c2)CC2CC(O)C1N2C +Cc1nc2ccccc2c(Nc2ccc(N3CCN(C)CC3)cc2)c1C(C)C +CCc1cccc(NC(=N)Nc2cc(C(F)(F)F)cc(CC)c2Cl)c1 +CN(C)CCn1c(CC(C)(C)C)nc2cc(S(=O)(=O)C3CN(C)C3)ccc21 +C=CC(=O)Nc1cc(CCn2c(=O)c(-c3cc(OC)cc(OC)c3Cl)cc3cnc(NC)nc32)ccn1 +CN(C)CC(=O)N1CCC(CNC2CC2c2ccccc2)(Cc2cccc(C#N)c2)CC1 +NC1=NC(CF)(c2cc(Nc3ncccc3F)ccc2F)CC(C(F)(F)F)O1 +Cc1ccc(-c2c(NS(=O)(=O)c3ccc(Br)cc3)ncnc2OCCOc2ncc(Br)cn2)cc1 +O=C(NCC(CCN1CCC(N2CCCCC2)CC1)c1ccc(Cl)c(Cl)c1)Nc1cc(Cl)cc(Cl)c1 +COC(=O)C1CC(NC(=O)c2ccc(OC)cc2OC)CN1CC(c1ccccc1)c1ccccc1 +COc1cccc(-n2ncc3c(NN=Cc4ccc(OCCN(C)C)cc4)ncnc32)c1 +O=C(c1cnccc1Oc1ccc2ncsc2c1)N1CCN(C2CC2)c2ccccc21 +c1ccc(-c2csc3nc(N4CCC(COCCN5CC6CC5CO6)CC4)ncc23)cc1 +C#Cc1cccc(Nc2ncnc3cc(NC(=O)c4ccc(C(=O)Nc5ccccc5N)s4)ccc23)c1 +COC1CCC2(CC1)Cc1ccc(-c3cncc(F)c3)cc1C21N=C(N)N(C(C)C)C1=O +O=C(CCN1CCCC1)Nc1ccc2c(NC3CCCCC3)c3cc(NC(=O)CCN4CCCC4)ccc3nc2c1 +CC(NC(=O)C1(NC(=O)c2ccno2)COC1)c1ccc(-c2cc(Cl)cc(Cl)c2OCC(F)F)cc1F +CC(=O)N1CCOCC1COc1cc(Cl)c(-c2noc(-c3cc(C)nc(NC(C)C)c3)n2)cc1F +O=c1[nH]c(C2CCC(c3ccccc3)CC2)c(Cc2cccc(C(F)(F)F)c2)c(=O)[nH]1 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+COc1ccc2c(OCc3nnc4ccc(-c5cc(F)cc(F)c5)nn34)ccnc2c1 +Cc1noc(=O)c2ccc(NC(=O)C(O)(CC(C)(C)c3cccc4c3OCC4)C(F)(F)F)cc12 +CC(=O)C1=NN(c2ccc(S(N)(=O)=O)cc2)C(=C(C#N)C(=O)Nc2ccc(S(N)(=O)=O)cc2)S1 +O=C(O)CCOc1ccc(C2Oc3cc(O)ccc3C3=C2c2ccc(O)cc2OCC3)cc1 +COc1cc(C(=O)c2ccc3c(c2)c(C=O)cn3C)cc(OC)c1OC +O=C1CC(c2c(Cl)ccc(N3CCNCC3)c2Cl)CC(O)=C1Sc1ccccc1Cl +Nc1nccc2cc(CC(C(=O)O)N3CCC(NS(=O)(=O)c4cnc(N5CCC(F)(F)C5)s4)C3=O)c(Cl)cc12 +O=C(Nc1ccc(O)cc1)c1ccc2c(-c3nc4ccccc4[nH]3)n[nH]c2c1 +CC(O)c1nccc(N2CCN(c3nccc(-c4ccccc4)n3)CC2)n1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(Oc4cc(Cl)ccc4F)nc23)N1 +N#Cc1ccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)cc1 +O=C(O)C=CC(=O)Nc1cc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)ccc1O +CC(C)(CNC(=O)C1CC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +O=C(O)C1C(Cn2c(=O)nc3ccccn3c2=O)CCC1Sc1ccc(-c2ccc(Cl)cc2)cc1 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(OC(=O)NC1CCCCC1)C(=O)CO +CCCN(CCC)C(=O)C=Cc1c(-c2ccc(Cl)cc2)[nH]c2ccccc12 +CN(C)c1ccc(-c2nc3ncnc(N)c3cc2-c2ccc(C(C)(C)C)cc2)cc1 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+O=c1c(=Cc2ccccc2Cl)sc2nc3cc(Br)cnc3n12 +COc1cccc2c1nc(CCn1c(=O)n(C)c3cccnc31)n2-c1ccccc1 +Cc1nc(NCC2CC2)nc(NC2CC(CO)C(O)C2O)c1-c1nc2ccccc2s1 +CC(C)c1ccc2nc3ccc(C(=O)NCCCCc4cccnc4)cn3c(=O)c2c1 +O=C(O)CNC(=O)C1=C(O)CCN(Cc2cnc(Oc3ccc(C4CC4)cc3)cn2)C1=O +Oc1ccc(-c2nn(C3CCCCC3)c3c(Cl)cccc23)cc1 +Cc1ncn(-c2ccc(CN3CC(N)C(C(=O)N4CCCC4C#N)C3)cc2)n1 +CCOc1ccc(Cc2cc(C3OC(OCc4ccccc4)C(O)C(O)C3O)ccc2Cl)cc1 +N#Cc1ccc(-c2ccc(NCCC3CCN(Cc4ccccc4)CC3)nn2)cc1 +COc1ccc(OCc2ccc(COc3c(Cl)cccc3Cl)cc2)c(Cl)c1 +Cn1cncc1C(OCc1ccc(C#N)cc1-c1ccc(C#N)cc1)c1ccc(C#N)cc1 +COc1ccc(C(Cc2ccncc2)c2ccc(NS(=O)(=O)c3c(F)c(F)c(F)c(F)c3F)cc2)cc1OC1CCCC1 +O=C(NCCSSCCNC(=O)C(Cc1ccc(O)c(Br)c1)=NO)C(Cc1ccc(O)c(Br)c1)=NO +Cc1nn(-c2c(F)cccc2CN(C)C)cc1CN1CCC2(CC1)OCC(F)(F)c1cc(Cl)sc12 +Cc1ccc(-c2nn(CCCCN3CCN(CC4COc5ccccc5O4)CC3)c(=O)c3ccccc23)cc1 +CCS(=O)(=O)N1CCN(C(=O)c2cccc(Cc3n[nH]c(=O)c4ccccc34)c2)CC1 +CS(=O)(=O)c1ccc(N2CCN(C(=O)c3cc(S(C)(=O)=O)ccc3OCC3CC3)CC2)c(F)c1 +N#Cc1ccc(-c2n[nH]c3c2Cc2ccc(OCCCN4CCOCC4)cc2-3)cn1 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+COC(=N)NS(=O)(=O)c1ccccc1[N+](=O)[O-] +CCC(C1CC1)n1cc(Cl)nc(Nc2cc(C)c(C)cc2C)c1=O +COc1ccc(F)cc1C(C)(C)CC(O)(CN1CCC(=O)c2ccccc21)C(F)(F)F +CCCCOc1cc(C(=O)Nc2c(Br)cncc2Br)ccc1OC +CN(C)c1cc[n+](Cc2ccc(CCCCc3ccc(C[n+]4ccc(N(C)c5ccc(Cl)cc5)cc4)cc3)cc2)cc1 +COCCCNc1nc(-c2ccc(N3CCOCC3)cc2)cc2ncn(C)c(=O)c12 +CCC(=O)N1CCC(N2C(=O)N(c3ccc(F)cc3)Cc3cnc(Nc4ccc(N5CCN(C)CC5)c(C)c4)nc32)C1 +CNc1nc(Nc2ccc(C(=O)N3CCC(OC)CC3)cc2OC)ncc1Br +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C1COC(=O)N1 +O=C(CN1CCN(Cc2ccc(Cl)cc2)CC1)N1CCSc2ccccc21 +CC(NC(=O)Nc1cc2[nH]nc(C(=O)NCC3CCN(C4CC4)C3)c2cn1)c1ccccc1 +COc1cc(C(F)(F)F)ccc1N1C(=O)COc2cc(S(=O)(=O)Nc3nccs3)ccc21 +Cc1cc(CN2CCNCC2)ccc1C(=O)Cn1ncc(OCc2ccc(Cl)cn2)cc1=O +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc(NC)cc2)cc1 +COc1ccccc1-n1cc2nc(Cc3ccccc3)nc(N)c2n1 +Cc1cccc2cc(C(C)Nc3ncnc4[nH]cc(C#N)c34)n(-c3ccccc3)c(=O)c12 +C=Cc1c[nH]c(=O)c2c1cc(CCCN)c1ccc(-c3cn[nH]c3)cc12 +NC(=O)n1cc(NC(=O)N2CC(F)CC2C(=O)NCc2cccc(Cl)c2F)c2ccc(O)cc21 +CC(C)(C)c1cc(N2CCC(=O)NC2=O)cc(C(=O)Nc2cccc(NS(C)(=O)=O)c2)c1O +CC(NC(=O)N1CCC(C(=O)Nc2cnccn2)CC1)C(=O)NC(CCc1ccccc1)C(=O)NCc1ccccc1Cl +O=C(NCc1ccccc1)c1c(NO)cc(-c2ccccc2)oc1=O +Cc1nnc(C(C)C)n1C1CCN(CCC(NC(=O)C2CCC(F)(F)CC2)c2ccccc2)CC1 +CCCCC1CN(CC2CCC(OCC)CC2)C(=O)OC12CCN(C1CC3CN(C(=O)c4c(C)ncnc4C)CC3C1)CC2 +COc1ccc(C)cc1NC(=O)OC1CC2CCCC(C1)N2CCF +Cc1cc(-c2cnn(C(CO)CO)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +Cc1c(Nc2c(C#N)cncc2-c2cc3cc(CN4CCNCC4)ccc3o2)ccc2[nH]ccc12 +O=C(CCCCCC(NC(=O)c1ccccn1)C(=O)NCc1ccccc1)NO +COc1cc(OCc2csc(-c3ccc(CO)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +COc1cc(C(=O)N2CCS(=O)(=O)CC2)ccc1Nc1cc2cc(-c3cnn(CC(C)(C)O)c3)ccc2cn1 +CCOC(Cc1ccc(OCCC2c3ccccc3-c3ccccc32)cc1)C(=O)O +O=C1c2ccc(O)cc2C23CCCCC2C1N(CC1CCC1)CC3 +O=C1CC(C(=O)O)Oc2ccc(OCc3cccc(OCc4ccc5ccccc5n4)c3)cc21 +O=C(NC1C(=O)N(c2ccccc2)CC1C(=O)O)c1ccc2ccccc2c1 +CC(c1ccc(-c2ccc(=O)n(C)c2)cc1)C(N)C(=O)N1CCC(F)C1 +Nc1c(C(=O)c2ccccc2Cl)cc[n+]([O-])c1-c1ccccc1Cl +Nc1cc2c3c(c1)c(C(F)(F)F)c(CCCc1ccccc1)n3CCC2 +COc1cc(NS(=O)(=O)Cc2ccc(Cl)cc2)ccc1-c1cncnc1C +CCNC(=O)C1OC(n2cnc3c(N)nc(N4CCN(c5ccc(OCC(=O)OCC)cc5)CC4)nc32)C(O)C1O +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C(F)(F)F)no4)c3)c2cc1OC +O=C(O)C1CCCN1C(=O)c1cccc(COc2ccc(-c3cccc4ccsc34)cc2)c1 +NS(=O)(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1 +S=C(NN=C(c1ccccc1)c1ccccc1)N1CCNCC1 +NCCc1cc2c(O)c(c1)Cc1cc(CCN)cc(c1O)Cc1cc(CCN)cc(c1O)Cc1cc(CCN)cc(c1O)C2 +COc1ccc2nc(NC(=O)C3CC3c3ccc(C#N)cc3)sc2c1 +Cc1cc(C)cc(Oc2c(Cn3ccnc3Br)c(C)[nH]c(=O)c2I)c1 +O=C(NCC1CCCCN1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 +CCN(CC)c1cc2oc3cc(=[N+](CC)CC)ccc-3nc2c2ccccc12 +CC(C)N(C(=O)C1CCC2C3CNC4=CC(=O)CCC4(C)C3CCC12C)C(C)C +Oc1noc(C2CCNCC2)c1C(Br)c1ccc2ccccc2c1 +O=C1NCCCCC1N(Cc1cccnc1)S(=O)(=O)c1ccc(Cl)cc1 +CC#CC(=O)Nc1cc(-c2cnc3[nH]cc(Cl)c3c2)ccc1F +CC(NS(=O)(=O)c1ccc(-c2nc3cc(C(N)=O)ccc3[nH]2)cc1)c1ccccc1 +N#Cc1ccc(-c2cccnc2OC2CC(Nc3nc4ccccc4s3)C2)cn1 +NC1CCN(c2cc(Cl)ccc2C=C2SC(=O)NC2=O)C1 +CC(=O)c1cn(CC(=O)N2CC(C)(F)CC2C(=O)NCc2cccc(Cl)c2F)c2cnccc12 +O=S(=O)(c1cccc2ccccc12)c1n[nH]c2cccc(NCC3CCNCC3)c12 +O=c1nc(OCC2COc3ncccc3O2)cc2n1CCc1cc(CN3CCOCC3)ccc1-2 +Nc1ncc(-c2ncccc2OC(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)(CO)CC1 +CC(C)C(C)Oc1ccnc(-c2ccnc(Nc3ccc4[nH]c(C(=O)N5CCN(C)CC5)cc4c3)n2)c1 +Cc1ccc(-c2ncccn2)c(C(=O)N2C3CCC2C(Nc2ccc(Br)cn2)C3)n1 +CC(C)c1ccc(S(=O)(=O)c2n[nH]c3ccc(N4CCC(N)CC4)cc23)cc1 +CCC(Cc1ccccc1C)NS(=O)(=O)c1c(C)cc(C)cc1C +O=Cc1c(O)ccc2nc(-c3ccc(C(=O)N4CCCC4)cc3)ccc12 +COc1ccccc1CNc1ccc2c(c1)n1ncc(I)c1n[n+]2[O-] +COC1CCN(c2c(NC(=O)c3nc(-c4ccccc4F)sc3N)cnn2C)CCC1N +O=C(CCCCCCOc1ccc(N(Cc2ccncc2)C(=O)CCc2c[nH]c3ccccc23)cc1)NO +CN1C(=O)NCC1C(=O)NCc1ccc(Cl)c(C(F)(F)F)c1 +OC1CCc2ccccc2C12CCN(CCc1ccccc1)CC2 +O=C(c1ccccc1)N1CCN(C(c2cncnc2)c2ccc(Cl)cc2F)CC1 +CCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NCc2ccc3ncccc3c2)C2CCC2)nn1 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(SCc3cccs3)c2[nH]1 +COC(=O)c1ccc(CNc2nc(Nc3cc(C)[nH]n3)cc(N3CCOCC3)n2)cc1 +Clc1ccc(-c2cc(C3CCN(Cc4ccccc4)C3)[nH]n2)cc1 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(Cc2ccccc2)C1 +COc1cccc(C=CCC(=O)Nc2nc3ccccc3c(=O)s2)c1 +CN1CCN(c2cccc(Nc3nc4c(OCc5ccccc5C(N)=O)cccn4n3)c2)CC1 +CSCC12CCC(=O)C=C1CCC1C3CCC(=O)C3(C)CCC12 +O=C1c2ccc(Cl)c(Cl)c2C(=O)N1CCCn1ccnc1 +CC1(c2sc(-c3cncc(C(F)(F)F)c3)cc2Cl)CS(=O)(=O)C2(CCOCC2)C(=N)N1 +N=c1oc2c(O)c(O)ccc2cc1C(=O)NCCNC(=O)c1cc2ccc(O)c(O)c2oc1=N +CN1CCN(c2ccc3c(c2)c(S(=O)(=O)c2cccc4ccccc24)nn3Cc2ccccc2)CC1 +Fc1cccc(COc2ccc(Nc3ncnc4ccc(NC(=S)NCCN5CCCCC5)cc34)cc2Cl)c1 +Cn1c(=O)n(C)c2cc(-c3[nH]cnc3-c3ccccc3)ccc21 +O=C(CCCOc1ccc2[nH]c3nc(O)nc-3cc2c1)N1CCN(c2ccccc2)CC1 +O=C(NCCN1CCOCC1)c1cc(N2CC2)c([N+](=O)[O-])cc1[N+](=O)[O-] +COC(=O)CS(=O)(=O)c1nc2ccc(S(=O)(=O)N3CCOCC3)cc2c2c1C(=O)N(CCOC(C)=O)C2=O +CN1C(Cc2c[nH]c3ccc(-n4cnnc4)cc23)CC2CN(CCc3cccc(F)c3)CC21 +NCCCCC(NC(=O)CCCCCNC(=O)C1OC(n2cnc3c(N)ncnc32)C(O)C1O)C(N)=O +CCN1C(=O)C2(CCc3cc(OC)ccc32)C(=O)N(c2ccccc2)c2cc(C(F)(F)F)ccc21 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1Oc1ccc2ccccc2c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(C=NOC(C)(C)C)c(O)ccc3nc2-1 +Cc1ccc2cc(Cn3cc(C(=O)NCc4ccc(N)nc4C)cn3)ccc2n1 +CC1(C)CC(NC(=O)Nc2ccc3c(c2)NC(=O)CC3)c2ccc(Cl)c(F)c2O1 +CC(C)N(Cc1nc2c(c(=O)[nH]1)COCC2)C(=O)CN1CCC(C(=O)c2ccc(F)cc2)CC1 +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NCc1nnn(C)n1 +CCOC(=O)C(c1ccccc1)N1C(=O)C(C)Oc2cc(F)c(N3C(=O)C4=C(CCCC4)C3=O)cc21 +CCCNc1cc(NCCSCc2ccc(CN(C)C)o2)c([N+](=O)[O-])cc1[N+](=O)[O-] +O=c1ccc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n1C1CCCC1 +CC1CCC2C(C)C(CC(=O)Nc3ccc(Cl)c(-c4ccccn4)c3)OC3OC4(C)CCC1C32O4 +O=S(=O)(c1ccccc1)N(c1ccccc1)c1ccccc1 +CNc1ncc(-c2ccnc(NC3CCC(N)CC3)n2)c(CC2CC2)n1 +COC(C)(C)CC1n2cncc2CN(C(C)c2ccc(Cl)cc2)S1(=O)=O +COCCNc1ncc2ncnc(Nc3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3C)c2n1 +Cc1nc(-c2ccc(OCCCOc3ccc4c(c3)CCC4CC(=O)O)cc2)sc1C(=O)O +CCN(C(=O)c1ccc(-c2ccc(OC)cc2)[nH]c1=O)c1ccc(OC)nc1 +CCOc1cccc(C=NNc2ccc(S(=O)(=O)N(CC)CC)cn2)c1O +c1coc(CNc2ncc(-c3ccc(CN4CCCC4)cc3)c3nncn23)c1 +O=C(c1ccc2[nH]c(=O)c3c(c2c1)CCSC3)N1CCN(CCc2ccccc2)CC1 +CC(=NNC(=O)C1CC1c1ccccc1)c1cccc(O)c1 +O=C(OCCN1CCCC1)N1c2ccccc2Sc2ccccc21 +COc1ccc(NCCNC(=O)C(CC2CCCCC2)NC(=O)c2cccc(Oc3ccccc3)c2)cc1 +Cc1nc(O)c2c(n1)CCc1ccc(S(=O)(=O)Nc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)cc1-2 +CNC(=O)c1csc(NC(=O)c2ccc3[nH]c4c(c3c2)C(C)CNC4=O)n1 +N=C(N)NCCCNc1ccnc2c1ccc1c(NCCCNC(=N)N)ccnc12 +CCCCOc1ccc(OC(=O)Nc2cc(Cl)ccc2OC)cc1 +CC(C)(C)c1cc2[nH]c(=O)n(O)c(=O)c2s1 +CNCCCN1Cc2ccccc2N(c2ccccc2)S1(=O)=O +COc1ccc(-c2cc(=O)[nH]c(=S)n2CC(=O)NCCN)c(OC)c1 +COc1ccc(NC(=N)NCCCOc2ccc(F)cc2)cc1 +O=C1c2ccccc2CCCN1CCCCN1CCN(c2nsc3ccccc23)CC1 +CCCCCNC(=O)NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Oc1cccc(Cl)c1 +NC(=O)COc1cccc(C=C2SC(=S)N(CC(=O)O)C2=O)c1 +CN(c1ccc(S(=O)(=O)NC2c3ccccc3CC2O)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +CN1CC2CC1CN2c1cnc(-c2ccc3[nH]ncc3c2)cn1 +COc1cc(OC)c(Cl)c(-c2ccc(C(=O)Nc3ccc(CN4CCN(C)CC4)cn3)c3nccnc23)c1Cl +O=C(c1ccccc1)N(N=C1C(Cl)=C(Cl)C(Cl)=C1Cl)C(=O)c1ccccc1 +COC(=O)c1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC(C)(C)C1 +CC(C)c1nc(-c2ccccc2)cc(-c2ccc(F)cc2)c1C=CC1CC(O)CC(=O)O1 +N=C(NCCCNCCCCCCCNCCCNC(=N)NCc1ccccc1)NCc1ccccc1 +Cc1ccc(S(=O)(=O)N=S(C)(=O)n2cc3c(n2)CN(C2COC(c4cc(F)ccc4F)C(N)C2)C3)cc1 +Cc1cccc(CNc2ccc(-c3ccc(Cl)cc3)cc2)c1-c1ccc(C(=O)NCCC(=O)O)nc1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(Cl)cc2)n(-c2ccccc2)n1 +Oc1ccc(C2Oc3cc(O)c(Cl)c(O)c3C(Cl)C2O)cc1O +CC(C)(Cc1cc2ccccc2[nH]1)NCC(O)COc1ccccc1C#N +Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NN)cc1 +O=c1cc(-c2ccccc2)oc2c3c(ccc12)OCC=C3 +CCN1C(=O)CC(C)(C)c2cc(C)c(-c3cc(CCC(=O)O)ccc3OC(F)(F)F)cc21 +CC1(F)CC(C(=O)NC(CO)c2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 +CS(=O)(=O)CCOC12CCCCC1(S(=O)(=O)c1ccc(Cl)cc1)c1c(F)ccc(F)c1OC2 +CS(=O)(=O)Nc1ccc(C(O)(c2ccc(Cl)cc2)c2cccnc2)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2cccc(OC(C)C)c2)cc1 +CC1CCC(NC(=O)C(N)Cc2nc(-c3ccc(O)cn3)no2)=C(C(=O)O)C1 +O=C1CCC2(OCCCc3ccccc3)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +CCC1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1CC(C)C +CCCC1(CCC)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)=C(O)O1 +CCc1cccc(OC)c1NC(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)cc1 +CC#CNC(=O)C12CNCCC1(c1ccc(Cl)c(Cl)c1)C2 +COc1ccc(-c2nc3c(N4CCN(Cc5ccc(Cl)cc5)CC4)c(Br)cnc3[nH]2)cc1 +CC(C)(N)C1CCC(Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1 +CN(C)CCN1C(=O)CCc2cc(NC(=N)c3cccs3)ccc21 +O=C(Nc1ccc(Oc2ccc(Cl)cc2)cc1)c1cc(I)cc(I)c1 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCNCC4)no2)cc1Cl +NC(CSC1(c2ccc(C(F)(F)F)cc2)c2ccccc2C=Cc2ccccc21)C(=O)O +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)C2CCCCC2)c1 +CC1CCCN1c1cccc(Nc2cc(-c3ccc(OCCN4CCCC4)cc3)nn3ccnc23)n1 +COC(=O)CCCCC(=O)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1C(=O)NCc1cccnc1 +O=C(Nc1ccccc1C(=O)O)c1cc(O)c(-c2ccccc2)c(Oc2ccccc2)c1 +CC(C)n1c(=O)c(C(=O)NC2CC3CCC(C2)N3CCCCCCCN2CCOCC2)cc2ccccc21 +CCc1cc(SCc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OC(F)C(=O)O +CC(C)n1cnc2c(NCc3ccc(-c4ccccc4Cl)cc3)nc(NC3CCC(N)CC3)nc21 +CCn1cnc2c(Nc3ccc(P(C)(C)=O)cc3)nc(NC3CCOCC3)nc21 +CCNCCNc1cc(-c2ccc(S(C)(=O)=O)cc2)c(C#N)c2nc3ccccc3n12 +C#Cc1cccc(CC(NC(=O)COC)C(O)CNC2CC3(CCC3)Oc3ncc(CC(C)(C)C)cc32)c1F +CC(CNc1cccc(S(C)(=O)=O)c1)NC(=O)C(CC1CCCCC1)Nc1nc2cccc(Cl)c2o1 +COc1ccc(-c2[se]ncc2-c2ccc(Cl)cc2)cc1 +CCN1CCN(c2cncc(-c3cn(-c4cc(C(=O)Nc5cc(C(C)(C)C)on5)ccc4C)nn3)c2)CC1 +O=C(NC1CCOCC1)c1ccc(OCc2c(-c3ccc(F)cc3)noc2C(F)(F)F)nc1 +CN(c1cc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)C1CCOCC1 +O=C(CCCCC1CCSS1)Nc1ccc2c(c1)CC(C(=O)O)OC2 +CCNC(=O)Nc1cc2c(-c3ccncc3)ccc(Oc3cccnc3)c2cn1 +CN1CCN=C1c1ccc(NC(=O)c2nnnn2-c2cc3ccccc3cc2F)c(F)c1 +O=C(c1ccccc1C(F)(F)F)N1CCC(Cc2ccccc2)CC1 +COc1cc(-c2ccc3nc(NC(C)=O)sc3c2)cnc1N +CN(CCCN1c2ccccc2CCc2ccccc21)CCOCCOCCN(C)CCCN1c2ccccc2CCc2ccccc21 +COCc1cc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)ccc1F +O=C1N=C(NCCc2cccc(Cl)c2)SC1=Cc1ccc2ncccc2c1 +Oc1c(CN2CCCCCC2)ccc2c1CCN(CCCC(c1ccccc1)c1ccccc1)C2 +Cc1cc(C(F)(F)F)ccc1Nc1nc(SC2CCOC2C)nc2c1CCN(c1ncccc1C(F)(F)F)CC2 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(-c3ccsc3)c2)CCCCC1 +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(C1=C(O)C3CC=CCC3N(Cc3ccc(F)cc3)C1=O)N2 +COc1ccc(S(=O)(=O)c2ccc(C(C)N3CCN(C4CCN(C(=O)c5ccccc5C)CC4)CC3C)cc2)c(OC)c1 +O=C(c1ccccc1)N(Cc1cnccc1-c1ccccc1F)S(=O)(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1ccc(CCC(=O)N2CCN(C(=NC#N)Nc3ccccc3C)CC2c2ccccc2)cc1OC +Cc1ccc(S(=O)(=O)NC(C(=O)NC(C=O)CC(C)C)C(C)C)cc1 +CCCOc1cccc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)c1 +CC(=O)c1cnc2ccc(-c3cc(F)c(O)c(F)c3)nc2c1NC1CCC(CN(C)C)CC1 +O=C(O)c1ccc(-c2nc(-c3ccc4oc5c(C(=O)O)cccc5c4c3)cs2)cc1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc(OC)c(C#N)c2)n1 +CCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(CN3Cc4ccc(OCC5CC5)cc4C(F)C3)cc2)s1 +O=C(Nn1c(=S)[nH]c2ccc(F)cc2c1=O)c1ccc(CN2CCCCC2)cc1 +COc1ccc(-c2c(-c3cc(Br)c(OC)c(OC)c3)ncn2C)cc1F +CS(=O)(=O)NC(=O)CCCc1c(-c2ccc(F)cc2)[nH]c2ccc(Br)cc12 +Cc1ccccc1C1CN(CCCc2cn(CCCN3CCN(c4ccccc4O)CC3)nn2)CCc2cc(O)c(O)cc21 +CCC(CC)CC1(O)CCN(C(=O)Nc2cc(Oc3ccc(F)cc3)cc(Oc3ccc(C(=O)N(C)C)cc3)c2)CC1 +COc1ccc2c(c1)OCC1C2C2=C(OC1(C)C)C1=C(C(=O)C2=O)C2c3ccc(OC)cc3OCC2C(C)(C)O1 +COc1cc(-c2ccc3ncnc(Nc4cccc5[nH]ncc45)c3c2)ccc1F +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc(Br)c1 +O=C(NCCCN1CCN(c2ccccc2)CC1)c1ccc2c(c1)Cc1ccccc1-2 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+O=c1[nH]nc2[nH]c(CN3CCC(O)CC3)nc3cccc1c32 +CN1C(=N)NC(C)(c2sc(-c3ccnc(-c4cccnc4)c3)cc2F)CS1(=O)=O +CNC(C)C(=O)NC(C(=O)N1c2ccccc2CC1C(=O)Nc1c(F)cccc1F)C(C)C +CCNc1nc(N)nc2c1ncn2C1OC(C(=O)NC)C(O)C1O +CN1CCC=C(c2nsnc2SCCCCCCCSc2nsnc2C2=CCCN(C)C2)C1 +COc1ccc(-n2cnc3c(sc4ncnc(NCCCO)c43)c2=O)cc1 +CC1(C)C(O)C(C)(C)C1NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +O=CNC(=O)c1cnn2c1n[n+]([O-])c1ccc(Cl)cc12 +Cc1ccccc1C(=O)NN(C(=O)c1ccccc1Cl)C(C)(C)C +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccccc1Br +CCCCCCCC=CCC=CCC=CCC=CCCCC(=O)NCCO +CCCCOC(=O)N1CCC(Oc2ncnc3c2CCN3c2ccc(S(C)(=O)=O)cc2F)CC1 +COc1ccc(C=CC(=O)c2ccc(OCC(=O)NCCCCCCNc3ccnc4cc(Cl)ccc34)cc2)cc1 +CN(C)c1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)CN4CCC(CN)CC4)cccc2-3)cc1 +N#Cc1nc(N2CC(S(=O)(=O)c3ccccc3C(F)(F)F)CC2C(N)=O)cc(C(F)(F)F)n1 +N#Cc1cc(-c2ccnc(Nc3nccc(C4CCNCC4)n3)c2)ccc1OC1CCOCC1 +Cn1cc(-c2ccc(Nc3ncc4ccnc(NCC(C)(C)C)c4n3)c(OC(F)(F)F)c2)cn1 +CC(=O)OCC1OC(CCON=C2C3CCn4c(=O)n(-c5ccccc5)c(=O)n4C3C(O)C3OC23)C=CC1OC(C)=O 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+CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)CNC)cc13)N(C)S(=O)(=O)CC2 +CC(C(=O)NCCCNc1c2c(nc3ccccc13)CCCC2)c1ccc(-c2ccccc2)c(F)c1 +CN1CN(C2CCC(CNC3(C#N)CC3)CC2)c2c(cnc3[nH]ccc23)C1=O +Cc1cc(C)nc(N2CC3CN(C(=O)c4cc(F)ccc4-c4ncco4)CC3C2)n1 +Cc1ccc(CN2CC(C)C(c3nn4c(C5CCOCC5)ncc4c(=O)[nH]3)C2)o1 +O=C(OC1(C2CCCC(c3cccc(F)c3)N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC(O)(C2CC2)CC1 +N#Cc1ccc(CN2CCCC(NC(=O)c3ccc4[nH]nc(-c5ccc6c(c5)CCO6)c4c3)C2)cc1 +CC(C)(NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1)c1nccs1 +COC(=O)c1cc(Br)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CCc1nc(N)nc(N)c1-c1ccc(N(CC)Cc2ccccc2)c([N+](=O)[O-])c1 +Nc1ccc(S(=O)(=O)n2cc(C3CCN(Cc4ccccc4)C3)c3ccccc32)cc1 +O=C(Nc1ccc(Cl)cc1)N1CCN(Cc2cnc3ccccc3c2)CC1 +COC(=O)C1Cc2ccc(OCCc3nc(-c4ccc(C(C)(C)C)cc4)oc3C)cc2OC1=O +COc1ccc(CN2C(=O)C(=CC=Cc3ccc(N(C)C)cc3)c3ccccc32)cc1 +O=C(Nc1ccc(N2CCCCC2)cc1)N1CCc2nc[nH]c2C1c1ccc(Cl)cc1 +N=C(N)c1ccc(CNC(=O)C2CCCN2C(=O)C(CC(=O)N2CCOCC2)NS(=O)(=O)Cc2ccccc2)cc1 +Cc1ccc(C)c(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc32)c1 +O=C(O)C1(c2ccc3c(c2)OCC(Sc2ccccc2)C3O)CCCC1 +COC(=O)C(NC(=O)c1cc(-c2ccco2)nc2ccccc12)c1ccccc1 +Nc1ccc(-c2ccccc2F)cc1NC(=O)c1ccc(CNc2ccncc2)cc1 +Cn1c(C(=O)c2ccc(Oc3ncccc3-c3cc[nH]c(=O)c3)cc2)nc2ccccc21 +CCNS(=O)(=O)Oc1cc(C(C)(C)C)c(SC2=C(O)OC(CCc3ccc(O)cc3)(C(C)C)CC2=O)cc1C +Cc1ccc(CN2C(=O)CNC(c3ccccc3)(C(Oc3nc(C)cc(C)n3)C(=O)O)c3ccccc32)cc1 +CC1CN(c2ccc(C(=O)N(C)C)c(NS(=O)(=O)c3ccc(-c4ccccn4)s3)c2)CC(C)N1 +CC(OCC(O)CNC(C)(C)Cc1ccc2ccccc2c1)c1cccc(Cl)c1 +CC(C)Cn1c(CN)c(-c2ccccc2)c2cc(C(N)=O)ccc2c1=O +O=C(NO)c1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(=O)c2cc(Cl)cc(Cl)c2)cc1 +Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c2ccccc12 +O=C(Nc1ccc(C(=O)N2CCCC23CCNC3)cc1)N1Cc2ccc(F)cc2C1 +CCC1(S(=O)(=O)c2ccc(Cl)cc2)CC(CO)Oc2c(F)ccc(F)c21 +CC(c1nc2c(cnn2C2CCCC2)c(=O)[nH]1)N1CC(Cc2cccc(F)c2)C1 +O=C(NNc1ncnc2sc3c(c12)CCC3)c1ccccc1O +CC(=O)NCCNS(=O)(=O)c1cnc(-c2ccc(N(Cc3ccccc3)C(=O)c3ccc(O)cc3O)cc2)c(C)c1 +CC(NC(=O)C(C)(C)Oc1ccc(Cl)cc1)C(Cc1ccccc1Cl)c1ccccc1 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+COCCn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2sccc2Cl)CC3)cn1 +O=C(CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5ccccn5)n4)ccc3[nH]2)CC1)N1CCCC1 +CCc1ccccc1-n1nc(C)c(-c2ccc3nccnc3c2)c1Nc1ccc(OC)cc1C(=O)O +CCC(NC(=O)c1cc(C(=O)NCc2nccs2)c2n1CCOC2)c1ccccc1 +Cc1cccc(NC(=O)CN2CCC(c3cccc[n+]3[O-])CC2)c1 +O=C(O)C1(Cc2nc3cc(OCc4ccc5ccccc5n4)ccc3n2Cc2cccc(Br)c2)CCCC1 +Cn1c(=O)c2c(cc(-c3ccc4ccccc4c3)n2O)n(C)c1=O +COc1cccc(OC2=C(Cl)C(=O)c3c(OC(C)=O)ccc(OC(C)=O)c3C2=O)c1 +CCc1nc2c(C(F)(F)F)cccn2c1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1 +Cn1cnc2cc(Cl)c(NCc3ccc(C(=O)NCc4cccnc4)cc3)cc2c1=O +CC(C)CS(=O)(=O)N1CCC2(CCN(c3ccc(OC(F)(F)F)cc3)C2=O)C(O)C1 +CC12Cc3cnn(-c4ccccc4)c3C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(=O)COc1cnc2ccccc2n1 +CCCCCCC(c1ccccc1)N1CCC(O)(c2ccccc2)CC1 +CCOC(=O)C1CN(CCNc2nc3ccccc3n(C3CC4CCC(C3)N4C3CCCCCCC3)c2=O)CC1C(=O)OCC +CNC(=O)c1cc2c(Oc3ccc(-n4ccnc4)cc3)cncc2s1 +Nc1nc(N)c2nc(CNc3ccc(C(=O)NC(CCCNC(=O)CCC(=O)O)C(=O)O)cc3)cnc2n1 +CCc1cc(Cc2ccc(C(=O)NC3CCOCC3C(=O)NO)cc2)c2ccccc2n1 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+CC(C)c1cc(-c2ccccc2)c(-c2ccc(S(C)(=O)=O)cc2)c(=O)o1 +CC(C)CCc1nc(-c2ccc(OCCCN3CCCN(C(=O)C(C)NC(=O)c4ccco4)CC3)cc2F)no1 +NC1CCC(Nc2ccc3ncc(-c4ccc(Nc5ncccc5F)cc4)n3n2)CC1 +O=[N+]([O-])c1cn2c(n1)OC(COCc1ccc(OC(F)(F)F)cc1)C2 +Clc1cccc(N2CCN(CCCCn3cc(-c4ccc(-c5ccccc5)cc4)nn3)CC2)c1Cl +c1cncc(CN(CCCNCc2ccc3c(c2)OCO3)c2nc(-n3ccnc3)ns2)c1 +CN1CC(C(=O)c2cccs2)C(c2ccc(Cl)cc2)C1 +CCCN(CCC)C(=O)C1OC(C(=O)O)=CC(N)C1NC(C)=O +O=c1[nH]c2c(cc1CNCc1cccc(C(F)(F)F)c1)c(C1CC1)nn2-c1ccccc1 +CC(C)C(=O)N(CC=Cc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21)C(C)c1cc(F)cc(F)c1 +CCCN(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)C(c1ccc(Cl)cc1)C(C)C(=O)O +O=C(NN1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCc1c-2cccc1[N+](=O)[O-] +COC(=O)c1ccc(NC(=O)c2c(NO)cc(-c3ccccc3)oc2=O)cc1 +CCS(=O)(=O)CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(-c4cnn(C)c4)c2)CC3)n1 +CC(C)(C)C(=O)SCCOP(=O)(COCCn1cnc2c(N)ncnc21)OCCSC(=O)C(C)(C)C +CN(C)CCCOc1ccc(Nc2ncnc3ccccc23)c(CN(C)C)c1 +CN1CCSCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +Fc1cn(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 +Fc1ccc(OCCOc2c(-c3ccccc3)nc3ccccn23)cc1 +O=C(NC1CCS(=O)(=O)CC1)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O +COC1(c2cc(F)cc(OCc3cc(-c4ccccc4)n(-c4ccc(C)c(C)c4)n3)c2)CCOCC1 +CCc1cccc(CC)c1-c1cc(OC)c2c(n1)CCCC2Nc1cc(OC)ccc1C +CCN(C)C(=O)c1ccc2c(c1)NC(=O)C2=C(Nc1ccc(N(CCN(C)C)C(C)=O)cc1)c1ccccc1 +CCNC(=O)C1OC(n2cnc3c(N)nc(NCCc4ccc(CCC(=O)OC)cc4)nc32)C(O)C1O +COc1ccc2c(c1)c1c(n2Cc2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)CCN(CCC(=O)O)C1 +CC(=O)OCC12C(=O)C=CC(O)C13OC3CC1C3CCC(C(C)C4CC(C)=C(C)C(=O)O4)C3(C)CCC12 +COc1cc(Nc2ncc3ccn(-c4cccc(C(=O)NCCN5CCCC5)c4)c3n2)cc(OC)c1OC +Cc1cc(O)cc(C)c1CC(N)C(=O)NC1CCCc2ccc(Cc3cccc4ccccc34)cc21 +CC(C(=O)O)c1ccc(C(c2ccc(F)cc2)N2CCC(C(F)(F)F)CC2)c(-c2ccc(C(F)(F)F)cc2)c1 +CCc1c(C(=O)C(N)=O)c2c(CC(=O)O)cc(C)cc2n1Cc1ccccc1 +O=C(O)c1ccc2c(c1)nc(-c1ccc(OCc3ccccc3)cc1)n2C1CCCCC1 +CCN1C(=O)c2c(ncn2Cc2ccc(OC)c(Cl)c2)N2C1=NC1CCCC12 +CCC1CC(N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(C)=O)c2nc(OC)ccc2N1C(=O)OC(C)C +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-n2cncn2)c1 +CCCCCCC(=O)OC1c2cc3c(cc2C(c2cc(OC)c(OC)c(OC)c2)C2C(=O)OCC12)OCO3 +Cc1cc(Cl)c(OCCOc2ccc(C3=C(C(=O)N(Cc4cccc(Cl)c4Cl)C4CC4)CNCC3)cc2)c(Cl)c1 +CCc1nn(Cc2ccc(NC(=O)C(C)(C)C)cc2)c(CC)c1CC(=O)O +Cc1nc(N)nc(-c2cccnc2Nc2cnc(C)c(NS(C)(=O)=O)c2)n1 +CN(c1ccccc1)c1ncc(Br)c(Nc2cc(C3CC3)[nH]n2)n1 +O=C(O)CS(=O)(=O)c1ccc(C(=O)NCC(c2cccnc2)N2CCOCC2)cn1 +COc1ccc2nc3cc(Cl)ccc3c(NCCCCCCCCCCCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1 +CC(C)Nc1cc(-n2ccc3cc(CNC(=O)C4CCOC4)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +O=C1NC(=O)c2c1c1c3ccccc3ncc1c1[nH]c3ccccc3c21 +COc1ccncc1C#Cc1c(Cl)nc(N)nc1NC1CC(CO)C(O)C1O +Cc1ccc(N2CCc3ncnc(NCc4ccc(Cl)nc4)c3C2)c(C#N)c1 +COC1CN(c2cccc(-c3cccc(C)c3OCc3cc(F)c4c(c3)CCN(C3CCOCC3)CC4)n2)CCC1C(=O)O +CCCc1ccc(C(=O)O)cc1CCn1cnc2c1NC=NCC2O +O=C(O)c1ccc2c(c1)nc(-c1ccc(O)cc1)n2C1CCCCC1 +COc1cc(-c2nccc3[nH]c(-c4cccc5cc[nH]c45)nc23)cc(OC)c1OC +Cc1nc(N)nc(-c2cc(C(C)N3CCN(S(C)(=O)=O)CC3)cnc2Nc2cc(F)c3cccnc3c2)n1 +c1nc(NC2CCCCC2)c2cc(OCCN3CCOCC3)ncc2n1 +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4ccc5nc[nH]c5c4)c3)ncnc12 +CCNC(=O)Nc1ccc2ncc(Nc3ccc(OC)c(OC)c3)nc2n1 +CCC1CCCC(C2(OC(=O)N3CCN(CCO)CC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc(N2CCCNCC2)c(-c2cccnc2)c1 +CC(c1ccc(F)cc1)C(CS)C(=O)NC(Cc1ccc(O)cc1)C(=O)O +CCOC(=O)c1cc(Cc2ccc(Cl)cc2Cl)c(=O)n2c1CCC2 +COc1ccc(C(CS(C)(=O)=O)N2C(=O)c3ccccc3C2=O)cc1OC1CCCC1 +O=C(CN1CCCCC1)N1CCc2nc(-c3cc4cc(F)ccc4[nH]c3=O)[nH]c2C1 +CNC(=O)N1CCC(c2cc3c(-c4cncc(OCc5cccc(F)c5)n4)ccnc3[nH]2)CC1 +CNS1(O)CC(C)(c2cc(NC(=O)c3cnc(OC)cn3)ccc2F)NC(=N)C1(C)C +COC(=O)C1(c2ccc(NC(=O)c3nc(C#N)c[nH]3)c(C3=CCC(C)(C)CC3)c2)CCOCC1 +Cc1cn(Cc2cccc(C#N)c2)c2c(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cc(F)cc12 +COC1CCC2(CC1)Cc1ccc(-c3cc(C#N)ccc3F)cc1C21N=C(C)C(N)=N1 +O=C(NC1CCCC1Nc1ccc(C(F)(F)F)cn1)c1ccccc1Cl +Cn1cc(C(=O)Nc2ccc3oc(SCc4cccc(Br)c4)nc3c2)c(C(F)F)n1 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(=NOC4CCN(C)CC4)C5)cn3)n2)s1 +O=C(c1cc2ncc(Cl)cn2n1)N1CCc2[nH]c(=O)sc2CC1 +CCC(CO)Nc1nc(Cc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1 +Cc1cccc(-c2cnc(N)c(C(=O)NC3CCCC3)n2)c1 +Nc1ccc(-c2cccs2)cc1NC(=O)c1ccc(N2CCC3(CCN(CCO)C3)CC2)nc1 +Cc1c(Cl)cccc1N1CCN(CCCCOc2ccc3c(n2)NC(=O)CC3)CC1 +COc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)OCO3)cc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(C(=O)c2ccccc2)CC1 +O=C1C(c2ccc(F)cc2)=COC12CCN(Cc1ccc(F)cc1)CC2 +COCCCS(=O)(=O)c1ncccc1-c1ccc(-c2cnc(N)nc2)c(F)c1 +O=C(NCc1nc2ccccc2[nH]1)C1=CC(c2csc3ccccc23)CC(OCCCCO)O1 +CN1CCC(C(Oc2ccc(F)cc2)c2ccccc2)CC1 +Brc1c(Br)c(Br)c2[nH]c(NCCN3CCN(c4ncccn4)CC3)nc2c1Br +CC[S+]([O-])(=NC)c1ccc(Nc2ncc(C(F)(F)F)c(NC3CCCC3N(C)C)n2)cc1 +O=C(Nc1cccc(Br)c1)NC1CCC(OCc2c(F)cccc2F)CC1 +CC(C)(Cc1c[nH]c2ccccc12)NCC(O)COc1cccc2ccccc12 +Cc1c(S(=O)(=O)Nc2cncc(C(=O)O)c2)sc2ccc(C(C)C)cc12 +COC(C(=O)NC1CCC(OC(=O)CCc2ccccc2)CNC1=O)C(O)C(O)C(O)C=CC(C)(C)C +CNc1ccc(C(C)(C)C(=O)NC2C3CC4CC2CC(CC(N)=O)(C4)C3)cn1 +CCCCNc1nc(N)c2[nH]c(=O)n(Cc3ccc(N4CCOCC4)cc3)c2n1 +CC(C)CC(CP(=O)(O)C(N)CCc1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O +CNC(=O)NCCCCP(=O)(O)CC(CCc1ccccc1)C(=O)NC(CC(C)C)C(=O)Nc1ccccc1 +CC(C)CNc1cc(NS(=O)(=O)c2cccc(-c3ccncc3)c2)cc2c(Cl)[nH]nc12 +c1ccc2c(c1)c1cc[n+]2CCCCC[n+]2ccc(c3ccccc32)NCCCN1 +N#Cc1cccc(-c2ccc(N(CCN3CCC(O)C3)C(=O)Nc3ccc(F)c(C(F)(F)F)c3)cc2)c1 +COc1ccc(C(=O)Nc2ccc(F)c(C3(C(F)F)COCC(N)=N3)c2)nc1 +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)OC)cc3c(c2n1Cc1ccccc1)CCCC3 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1ccccc1-n1cnnn1 +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CCC1C(=O)N1CCC1 +COc1n[nH]c2cc(NC(=O)NC(c3ccccc3)C3CCCO3)ncc12 +Cc1nc(N)nc(-c2cc(Cl)cnc2Nc2cnc(C)c(NS(C)(=O)=O)c2)n1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1c1nc2ccccc2[nH]1 +O=C(NC(Cc1c[nH]c2ccc(O)cc12)C(=O)O)c1ccc2c(c1)nc(-c1ccoc1)n2C1CCCCC1 +Cn1c(C2(O)COC2)nc2c(N3CCOCC3)nc(-c3cnc(N)nc3)nc21 +Cc1ccc(NS(=O)(=O)NC(CNC(=O)CC2CC(c3ccc(C(=N)N)cc3)=NO2)C(=O)O)cc1 +O=C1NCCn2c1cc1cc(F)cc(-c3ccccc3)c12 +CC1(C)CC=C(c2cc(C3(O)CC4(CO)C=CC(CO)(C3)O4)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +O=C(O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c([S+]([O-])Cc3ccccc3)cccc21 +O=C(O)Cc1nn(Cc2ccc(Br)cc2F)c(=O)c2cc3ccccc3cc12 +COc1ccccc1-c1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2s1 +O=C(c1ccc(F)cc1)C1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1 +O=C(NC(Cc1c[nH]c2ccc(OCc3ccccc3)cc12)C(=O)Nc1ccncc1)C1CCCCC1 +CCOc1cc(CN2CCC(Nc3nc4ccccc4o3)CC2)ccc1Cl +COc1ccc2c(C)cc(NC3CCCC(NCc4ccsc4)C3)nc2c1 +CC1OC(=O)C2CC3CC(NC(=O)OC(C)(C)C)CCC3C(C=Cc3ccc(-c4cccc(C#N)c4)cn3)C12 +COc1ccc(NCCNC(=O)C(Cc2ccc(Cl)cc2)NC(=O)c2cccc(C)c2)cc1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1cccc([N+](=O)[O-])c1 +Cc1ccc(NC(=O)c2ccccc2)cc1Nc1ccc2c(c1)CCc1ccccc1C2=O +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCCC2)c1 +COCCN(C)C(=O)C1CCN(Cc2cccc(NC(=O)c3cncc(C)c3)c2)CC1 +O=C1NC(c2ccccc2)(c2ccccc2)C(=O)N1Cc1ccc(OCCCN2CCCCC2)cc1 +Cc1ccc2c(c1C)NC(=O)C2(c1ccc(O)cc1)C1CCCCCC1 +CC#CC(=O)N1CCC2(CC(n3nc(-c4ccc(Oc5ccccc5)cn4)c4c(N)ncnc43)C2)C1 +Cc1ncc(C)n2nc(CCc3cc(O)c4cc(F)ccc4n3)nc12 +CSc1ccc(-c2ccc(C(=O)NC3CCN(Cc4ccccc4)C3)cc2)cc1 +C[Si](C)(C)C#Cc1ccc2[nH]c3cnc(C(=O)OCC(F)(F)F)cc3c2c1 +CCC(C(=O)Nc1cc(F)c(C(=O)O)c(F)c1)n1cc(OC)c(-c2cc(Cl)ccc2C#N)cc1=O +Cc1c(CC(=O)O)cc2ccc(Cl)cc2c1-c1ccc(S(=O)(=O)NCCO)cc1 +CNC(=O)n1cc(NC(=O)N2C(C(=O)NC(CO)c3cccc(Cl)c3F)CC3CC32)c2ccccc21 +CC(NC(=O)Nc1cc2[nH]nc(N3CC(C)(O)C3)c2cn1)c1ccccc1 +CC(=O)Nc1n[nH]c2nc(N3CCCCC3)c3c(c12)CCN(Cc1ccccc1)C3 +O=C(O)CCC(O)c1ccc(C=Cc2cccc(Cl)c2)cc1 +CCOc1ccc(-c2nc(-c3ccc(C(=O)O)cc3)cs2)cc1OCC +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NCC2COCCO2)cc1 +O=C(NC(Cc1ccc2nc(-c3c(Cl)cccc3Cl)ccc2c1)C(=O)O)c1c(F)cccc1F +Cc1nc2ccccc2c(=O)n1-c1ccc(OC2CCC(N3CCCC3)C2)cc1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2ncc3ccccc3n2)C1 +COC(=O)c1c(C(=O)N2CCOCC2)cc2cc(OC)c(OC)cc2c1-c1cc(OC)c(OC)c(OC)c1 +CC(=O)c1cc(OCC(F)(F)F)c(=O)n2c1CCC2C(=O)N1CCCC1 +COc1cccc2c1S(=O)(=O)N=C2c1nc(Cc2ccc(F)cc2)c2ccccc2c1O +CC(C)c1cc(-c2ccc(C(N)=O)c(N)c2)c2cccc(-n3cnc(-c4cnn(C)c4)c3)c2n1 +CCCN1CCN(c2nc(CCN(C)C(=O)c3ccc(Cl)cc3)cs2)CC1 +COc1ccc(C2OC34CC(c5ccc(F)cc5)OC(=O)C3=CC2(C)OO4)cc1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccncn2)c1F +O=C1NC(=O)C2=C1c1cn(c3ccccc13)CCOC(CNCc1ccccc1)CCn1cc2c2ccccc21 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+O=[N+]([O-])c1cnc(Sc2nnc(Sc3ncc([N+](=O)[O-])s3)s2)s1 +CC1(C)OCc2c(Nc3n[nH]c4cccc(F)c34)nc(-c3cn[nH]c3)nc21 +CCN1C(=Cc2ccc3ccccc3[n+]2CC)Sc2sc3ccccc3c21 +CC(=O)N1CCN(C(=O)Cc2ccc(C(F)(F)F)cc2)C(CN2CCC(O)C2)C1 +CCc1ccccc1N(CC(=O)NCCc1ccc(OC)c(OC)c1)S(=O)(=O)c1ccc(Br)cc1 +CCCCCCNC(=O)Oc1cccc(CN(CCCOc2ccc3c(=O)c4ccccc4oc3c2)C(C)C)c1 +CC(C)CC(=O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NCC2CCOC2)CC1 +c1ccc(CN2CCN(CC3COC4(CCCCC4)O3)CC2)cc1 +COc1ccc(C)cc1S(=O)(=O)n1ccc2ccc(C(=O)Nc3ccc(C(=O)O)cc3)cc21 +CCOC(=O)CC(=O)OC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +O=c1oc2ccccc2n1C1CCN(Cc2ccccc2-c2cccnc2)CC1 +CN1CC(=O)N(CC(=O)NC(CC2CCCN(C(=N)N)C2)C(=O)c2nccs2)C(Cc2ccc3ccccc3c2)C1=O +CCC(N)c1ccc(Cl)c(C(=O)c2cccc(O)c2)c1F +CN1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)C2C1CCCC2N1CCC(O)C1 +CC(=O)Nc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +N=C(N)c1cccc(CNC(=O)c2c(Br)c3ccccc3n2Cc2cccc(C(=N)N)c2)c1 +NC(=O)c1cn(-c2ccc(S(N)(=O)=O)cc2)nc1-c1cccs1 +CCCc1ccc(C(=O)NN(C(=O)c2ccccc2Cl)C(C)(C)C)cc1 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+CCCCN(C)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)cc1 +CC(N=C(S)Nc1cc(Br)c(NC(=O)c2ccccc2F)c(Br)c1)c1ccc(F)cc1 +CCNc1cc(N2CCN(C(=O)c3ccc(CC)cc3)CC2)ccc1[N+](=O)[O-] +O=C1C(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)CCN1c1ccc(-c2cccnc2)cc1F +Nc1ccccc1NC(=O)CCCCCNC(=O)c1ccc2cn[nH]c2c1 +COS(=O)(=O)c1cccc(-c2ccoc2C2=CN3CCC2CC3)c1 +Cc1ccc(-c2cnc(Nc3cccc4c3CC(O)CC4)o2)cc1 +CNC(=O)C(NC(=O)c1cc(-c2ccccc2)nc2ccccc12)c1ccccc1 +c1ccc2c(c1)C1CC(c3nccs3)(c3nccs3)C2c2cccc[n+]21 +Cn1ncc(NC(=O)c2nc(-c3cc(F)ccc3F)sc2N)c1N1CCC(N)CC(F)(F)C1 +Cc1cc(-c2cn(CCN(C)C(C)C)c(C3CCN(c4ncnc(N)c4C(N)=O)CC3)n2)ccc1F +CCOc1ccc2[nH]nc(-c3cc(N4CCN(C5CC5)CC4)ncn3)c2c1 +CCS(=O)(=O)N1C2CCC1CC1(C2)OOC2(OO1)C1CC3CC(C1)CC2C3 +CCCCN(C)c1cccc(-c2cccc(NC(=O)Nc3ccc(Cl)cc3)c2)n1 +O=C(Cn1c(-c2nccs2)nc2ccccc21)Nc1ccc2ccccc2c1 +COC(=O)CCCCS(C)(=O)=NC(=O)c1cnc(N)c(C#Cc2cccc(NC(=O)c3cc(C)ccc3F)c2)c1 +CCCOc1ncc(C(C)=O)cc1-c1nc(=O)c2nn(C3CNC3)c(CC)c2[nH]1 +CCS(=O)(=O)c1ccc2c(c1)nc(CC(C)(C)C)n2CC1CC1 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+COc1cc(C=C2CC(C)CC(=Cc3cc(OC)c(OC)c(OC)c3)C2=O)cc(OC)c1OC +COc1cc(F)cc(-c2c[nH]c3ncnc(N4CCCC(O)C4)c23)c1 +CCOc1ccc(CN2CCCC(N3CCN(c4ccc(OC)cc4)CC3)C2)cc1 +CN(C)Cc1ccc(-c2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2)[nH]1 +CNC(=O)C(Cc1ccc(OC)cc1)NC(=O)C(CC(C)C)C(S)c1ccccc1 +CCCn1c(=O)c2nc(-c3cnn(Cc4noc(-c5cccc(Cl)c5)n4)c3)[nH]c2n(CCC)c1=O +CC(CCOC(=O)NCCCn1ccnc1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +CC1CN(C(=O)c2ccccc2)CCN1c1nnc(-c2ccc(C(N)=O)cc2)c2ccccc12 +Cn1ncc(NC(=O)c2nc(-c3cc(Cl)ccc3F)sc2N)c1C1CCC(N)C(F)CO1 +CCN(C(=O)c1cnn(-c2ccccc2)c1NS(=O)(=O)c1ccc(-c2cnco2)cc1)C1CCCCC1 +CN1CCC(Oc2cccc(CC(=O)Nc3nnc(CCCCc4ccc(NC(=O)Cc5ccccc5)nn4)s3)c2)CC1 +CCn1c(C(=O)NCc2cccc(Cl)c2)nc2c(-c3ccccc3)cccc21 +CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1ccc(I)cc1 +NS(=O)(=O)CCNC(=O)C(c1nc2ccc(-c3cncnc3)cc2s1)S(=O)(=O)Cc1ccc(F)cc1 +CC1(C)C2CC(CC=CCCCC(=O)O)C(NC(=O)c3ccc[nH]3)C1C2 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)c3ccc(C4CC4)nc3)cc12 +Fc1ccc(CN2CCC(CCNC(c3ccccc3)c3ccccc3)CC2)cc1F +CC1(C)CN=C(N2CCN(c3ncnc4sc(CCF)cc34)CC2)S1 +O=C1C=CC2C(=CC=C(O)O)c3ccc(O)c(O)c3OC2=C1O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ncc(Cl)cc4Cl)nc23)N1 +CCCn1c(=O)c2nc(C3CCC(=O)C3)[nH]c2n(CCc2ccc(N)cc2)c1=O +CC(C)c1cccc(C(C)C)c1NC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCC1CCCCC1 +CC(C)C(O)(CC(C)(C)c1ccccc1)C(=O)Nc1ccc2c(c1)COC2=O +CNCCN(c1cc(OC)cc(OC)c1)c1ccc2ncc(-c3cnn(C(C)C)c3)nc2c1 +CC1(C(=O)NNc2cccc3ncccc23)CC2C=CC1C2 +Nc1nc(C(=O)NCP(=O)(O)O)c(-c2cccs2)s1 +Cc1ccc(Oc2ccc(N(CC(NCc3ccncc3)C(=O)NO)S(C)(=O)=O)cc2)cc1 +Clc1ccc2c(NN=Cc3ccc4c(c3)OCO4)ccnc2c1 +COc1ccccc1OCCN1CCN(c2ccc(=O)n(CCN3CCN(c4ccccc4Cl)CC3)n2)CC1 +COc1ccc(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)c(Cl)c1 +CC1=CC2OC3C(O)C4OC(=O)C=CC=CC5OC(CC(C)=CC(=O)OCC2(CC1)C4(C)C31CO1)OC5C +COc1ccc(Cc2cc(C3CCN(C(=O)c4ccc5c(c4)OCO5)CC3)nc(N)n2)cc1 +N=C(NCCC(c1ccccc1)c1ccccc1)SCCCc1c[nH]cn1 +N=c1n(CCN2CCCCC2)c2ccccc2n1CC(O)c1ccc(Cl)c(Cl)c1 +CCc1nc(-c2ccccc2F)c(C(=O)N2CCN(c3cccc(OC)c3)CC2)o1 +CCCCCCCCC(NC(CC)C(=O)N1C(=O)N(Cc2ccccc2)CC1C(=O)O)C(=O)O +CSc1ccccc1N1CCN(CCCCCC(=O)NCc2ccncc2)CC1 +Cc1nc(NC(=O)N2CCN(C3CCCC3)C2=O)ccc1Oc1ccnc(-c2cnn(C)c2)c1 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OC4CCCCC4N(CC)CC)cc3)oc2c1 +COc1cc(-c2cn(C3CCCCN(CC(F)(F)F)C3=O)nn2)ccc1-n1cnc(C)c1 +NS(=O)(=O)c1ccc(C=NCc2ccc(O)cc2)cc1 +COc1cc(OCc2csc(N3CC4CCC(C3)O4)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +COc1ccc(-c2noc(C)c2C(=O)N=C(N)NCc2cc(C)c(NC(=O)C3CC3)c(Cl)c2)cc1 +CN(Cc1ccc(Cl)cc1)C(=O)C1CCOc2ncccc21 +COc1ccc2sc(C(=O)c3cc(OC)c(OC)c(OC)c3)cc2c1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(C=Cc4ccccc43)CC1)C(O)(CN1C(=O)CCC1=O)C2 +CCOC(=O)c1cc2c(n1CC)C(=O)C(Oc1ccc(OC)cc1)=CC2=O +O=C1c2ccccc2S(=O)(=O)N1c1c(F)c(F)nc(F)c1F +N#Cc1c(-c2ccc(F)cc2)c2c(=O)[nH]c(=O)[nH]c2[nH]c1=O +Cc1cc(-c2cccc(F)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +Cc1[nH]c2cc(C3CCCCN3C(=O)c3ccc(F)cc3NS(C)(=O)=O)nn2c(=O)c1C +CC1CN(c2scnc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cc1noc2ccccc12 +CCOc1c(OC)ccc2cc(C(=O)NCCc3ccncc3)c(=O)[nH]c12 +OCc1ccc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)cc1 +CN1CCN(CC(=O)Nc2cc(-n3cccn3)nc(-n3cccn3)n2)CC1 +CN(C)C(=O)Oc1ccc2sc(S(N)(=O)=O)cc2c1 +Cc1cccc(C2CN(C)CCc3c2cc(O)c(O)c3Cl)c1 +CC(C)CC(NC(=O)C(CCC(N)=O)NC(=O)C(CO)NC(=O)C(CO)NC(=O)OCc1ccccc1)B(O)O +Nc1ncc(-c2cc(C3C4CN(C5COC5)CC43)n(C3CCC3)n2)cc1C(F)(F)F +Cc1cc(C)cc(-n2cc(-c3ccccc3)c3c(=O)oc4ccccc4c32)c1 +Clc1cc2nc(N3CCN(Cc4ccccc4)CC3)c3cccn3c2cc1Cl +CC1CCN(C(=O)c2cccc(Sc3ccccc3Cl)n2)CC1 +CCOc1ccc2nc(NS(=O)(=O)c3ccc4c5c(cccc35)C(=O)N4CC)sc2c1 +CN(c1nc2ccc(NC(=O)CCc3ccc(C(F)(F)F)cc3)cc2[nH]1)C1CCCCC1 +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1)Nc1cc(C2CC2)ccc1F +C#Cc1cccc(-c2nc3ccc(C(F)(F)F)cn3c2NC(C)C)c1 +CCOC(=O)c1sc(Nc2nc(N3CCC(N(C)C)CC3)cc(N3CCNC(C(N)=O)C3)n2)nc1C +O=C(NCc1c(-c2ncco2)n(-c2ccccc2)c2ncccc2c1=O)c1ccc(N2CCC(CO)CC2)nc1 +CCN1C(=O)c2nc(-c3ccc(F)cc3)n(Cc3ccc(F)cc3)c2N2CC(C(C)C)N=C12 +CCN(CC1CC1)C(=O)c1ccc(-c2nc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)cs2)cc1 +CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(CC(C)C#N)c1 +CC(NC(=O)NC(CCCCNC(=O)c1ccc(I)cc1)C(=O)O)C(=O)O +COc1ccc(Br)cc1-c1nc(CNC2CCN(Cc3ccccc3)CC2)co1 +Cc1ncccc1Oc1ncnc(OC2CC3CCC(C2)N3C(=O)OC(C)C2CC2)c1C +COC(C)(C)C(O)C(=O)N1CC2CC2C1C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +C=CCN1C(=O)C(=Cc2ccc(O)cc2)SC1=Nc1cccc(C(=O)O)c1 +C#CCn1c(C)c(C(C)(C)C)sc1=NS(=O)(=O)c1ccccc1 +CCC(CC)(CO)COc1cccc2ccc(-c3nnc4ccccn34)nc12 +CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)ccc(C)c1C +COc1ccc(NS(=O)(=O)c2ccc(-c3cccs3)cc2C)cc1N1CC(C)NC(C)C1 +CN(C)c1ccc2c(-c3ccccc3)c3cc4ccc(=[N+](C)C)cc4cc3sc2c1 +CCCc1cnc(-c2ccc(-c3ccc(OCC(C)(C)C(=O)O)cc3)nc2)[nH]1 +NC(=O)c1ccc2[nH]c(-c3ccc(OC4CCC(O)CC4)cc3)nc2c1 +O=C(c1cc(-c2ccc(Cl)cc2Cl)n[nH]1)N(CCO)CCO +CC(NCCc1ccccc1F)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +CN(C)C1=NC2C(CC(C(C)(C)O)C(O)C2O)O1 +Cc1cccc(-c2ccc(OC(C)C)cc2)c1Oc1ccc(S(=O)(=O)Nc2ncns2)cc1C#N +CN(CCN1CCN(c2ccc(F)cc2F)CC1)c1nc(N)n2nc(-c3ccco3)nc2n1 +O=C(NC1CCCCC1)Oc1cccc(-c2cccc([N+](=O)[O-])c2)c1 +COCc1ccc(Oc2cc3[nH]c(-c4ccccn4)nc3cc2C2CCCN2C(C)=O)cn1 +O=C(NCCc1ccc(F)cc1)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +Fc1ccc(-n2cc(C3CCN(CCN4CCN=C4S)CC3)c3ccccc32)cc1 +COc1cc(OCc2csc(C3=CCC(C(=O)OC(C)(C)C)CC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C1NC(c2ccccc2)(c2ccccc2)CN1C1CCN(Cc2ccccc2)CC1 +NC(=O)C1CCC(CNc2nc(NCc3ccccc3)cc(-c3cccc(C(F)(F)F)c3)n2)CC1 +FC1CNCCCC1Oc1cccc2ccc(-c3nnc4ccccn34)nc12 +CC#CCn1c(N2CCCC(N)C2)nc2ccn(Cc3nc(C)c4ccccc4n3)c2c1=O +CC1CCC(Cn2c(N3CCCC34CCOC4)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +FC(F)(F)Oc1ccc(NC(=S)c2cnoc2C2CC2)cc1 +COc1ccc(C(=O)C=Cc2ccc(O)c(CN3CCN(c4ccnc5cc(Cl)ccc45)CC3)c2)c(OC)c1 +C=CC(=O)N1CCC(Oc2cc3c(Nc4ccc(F)c(Cl)c4F)ncnc3cc2OCCC)CC1 +CCNC(=O)c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F +CN1Cc2cc(C(=O)NCc3c[nH]cn3)ccc2NC(CC(=O)O)C1=O +NC1CN(c2ccc3nnc(C(F)(F)F)n3n2)CCC1c1cc(F)c(F)cc1F +CCCCCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(CF)CC21 +CCOc1ccc(Cc2nc3cc(C(=O)N4CCCCC4)ccc3n2CCC(C)C)cc1 +O=C1Nc2cc(Br)ccc2C1=C1Nc2ccccc2C1=NOCC(O)CO +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCN(c2ccccn2)CC1 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCCN4C(C)CCC4C)cc3)oc2c1 +Cn1c(-c2c[nH]nn2)nc(-c2ccc(F)cc2)c1-c1ccncc1 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1ccccc1Br)Oc1ccccc1-3 +CC(Nc1ncc(F)c(N2C(=O)OCC23CCCC3)n1)c1ccc(Oc2ccccc2)cc1 +COc1cccc2cc(CN(CCCCCCNc3c4c(nc5ccccc35)CCCCC4)Cc3cc4cccc(OC)c4o3)oc12 +Cc1nc(C)c2c(n1)N(Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)C(C)C2 +c1coc(-c2nc3nc(NC4CCCCC4)nc(NC4CCCCC4)n3n2)c1 +CN1CCC23c4c5ccc(O)c4OC2c2ncc(-c4ccc(Cl)cc4Cl)cc2CC3C1C5 +CCCc1nc(-c2cccc(C)c2)c(-c2ccnc(NC(=O)c3ccccc3)c2)s1 +CCc1ccc(S(=O)(=O)NCc2ccc(C(=O)NCCN(Cc3ccccc3)C(C)CC)cc2)cc1 +Fc1ccc2nc(Nc3nc(-c4ccccn4)cs3)sc2c1 +N#CCSc1nnc(Cc2c(NC(=O)CCl)sc3c2CCCC3)n1NC(=O)c1ccccc1 +Cc1ccccc1N1CC(C)n2nc(COc3ccc(Cl)cn3)cc2C1=O +CC(C)N(C)C(=O)Cn1c(-c2ccc(Cl)cc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CC(NC1CCN(c2ccc(C(=O)NC(CC(=O)O)C(=O)O)cc2)C1)c1cccc2ccccc12 +CC12CCC3C(CCC4CC(O)CCC43C)C1Cc1snnc12 +CNC(C)C(=O)Nc1ccc(-c2c(-c3cnn(C)c3)nc3cc(C)ccn23)c(C#Cc2ccc3c(C)nccc3c2)n1 +CCCOc1ccc(N2CCN(c3noc(CC)n3)C(C)C2)c(C)c1 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+CC(C)COC(=O)N1CCC(CN(C2Cc3cc(C#N)ccc3N(Cc3cncn3C)C2)S(=O)(=O)c2ccccn2)CC1 +CC(O)CNC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +CCOC(=O)c1c(C)nc2sc(C(=O)c3ccc(OC)cc3)c(N)c2c1-c1cc(OC)c(OC)c(OC)c1 +O=C(OCC#CCSc1nnc(-c2ccccc2Cl)o1)c1ccc(F)cc1 +CN(C)CCCOc1cccc(-c2n[nH]c3ccc(-c4nnn[nH]4)cc23)c1 +CC(C)Nc1nc(Nc2ccccc2)nc(Nc2ccc(F)cc2)n1 +COCCOc1cc(F)c(N2CCN(Cc3cccc(-c4cc5nc(-c6ccco6)nn5c(N)n4)c3)CC2)c(F)c1 +CN1C(=O)NC(=O)C12Cc1ccc(NC(=O)Cn3c(=O)n4c5c(cccc53)NC(=O)C4)cc1C2 +N#Cc1cc(-c2c[nH]c3ncccc23)cc(NCc2ccccc2)n1 +CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(Cn3ncc4ccccc43)n1CCO2 +COc1ccc(C(=O)C2CCN(C3CN(Cc4cccnc4)CCC3O)CC2)cc1 +CC(C)N1CCN(C(=O)c2ccc(CN3CCCCCC3)cc2)CC1 +Cc1nc2ccccn2c1C(=O)CN1CCN(c2ccc(F)cn2)CC1 +O=C(Nc1ccccc1)c1cccc(Oc2ccc3nccn3n2)c1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CC4CN(S(C)(=O)=O)CC4C3)cc12 +COC(=O)NC(C(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)cc3)ncc12)C(C)C +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)c2cc1OCCN1CCOCC1 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+CCCCNc1cc(NC(C)C(Cc2ccc(Cl)cc2)c2cccc(Br)c2)nc(C(F)(F)F)n1 +Cc1ccc(N2CCOCC2)c(N2CCN(Cc3ccc(F)cc3Cl)C(=O)C2=O)c1 +COc1cc(OC)c2c(c1)OC(c1cc(OC)c(OC)c(OC)c1)C(OC(=O)c1cc(OC)c(OC)c(OC)c1)C2=O +CCOc1cnc2cccc(-c3cc4c([nH]3)CCNC4=O)c2n1 +CC(=O)OC1CCC2(C)C(CCC3C2CCC2(C)C(c4ccc(=O)oc4)C(OC(C)=O)C(O)C32O)C1 +N=C(N)c1ccc2[nH]c(-c3n[nH]c(-c4ccccc4)c3O)nc2c1 +Cc1nnc(-c2ccc(C)c(-c3ccc(C(=O)NCc4ccc(NS(C)(=O)=O)cc4)cc3)c2)o1 +CC(C)(C)NS(=O)(=O)c1ccc(-c2cnc3cccc(Nc4ccccn4)c3c2)cc1 +COCC(O)Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cccc(Cl)c2)n1 +O=C(O)C1C(CC2CCNCC2)C(=O)N1C(=O)N1CCN(C(=O)Cc2ccc3c(c2)CCCC3)CC1 +CC(NC(=O)C1CCNCC1)c1ccc(Nc2ncc3cc(-c4ccncc4)ccc3n2)cc1 +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)CCCCCC(=O)NO)CC2 +Cc1ccc(CN2CC(COC(=O)c3cn(C)c4ccccc34)NC(=O)c3nn(CCc4ccccc4)cc32)cc1 +Cc1cc(OC(F)(F)F)ccc1-c1c(Oc2ccc(C=CC(=O)O)cc2)c2ccc(C(F)F)cc2oc1=O +C=CC(=O)NCCSc1nc(-c2ccc(F)c(C(F)(F)F)c2)c(-c2ccnc(Nc3ccccc3)c2)[nH]1 +CCCc1cc(C(=O)c2ccc(-c3ccccc3)cc2)ccc1OCCCn1ccc2cc(OC(C)(C)C(=O)O)ccc21 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+O=C(CC(=O)N1CCC(Cc2c[nH]cn2)CC1)Nc1cccc(Cl)c1 +O=C(CC12CC3CC(CC(C3)C1)C2)NC1CCC(Oc2ccc(F)cc2)CC1 +CS(=O)(=O)c1ccc(-c2nnn3c2CN(C(=O)CC(N)Cc2cc(F)c(F)cc2F)CC3)cc1 +CCn1nc(Cc2ccccc2)cc1C1CCN(CC2CN(C(C)(C(=O)O)C(C)C)CC2c2cccc(F)c2)CC1 +C#CCN(CCN1CCN(c2ccccc2OC)CC1)C1CCc2nc(N)sc2C1 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccccc3F)CC2)n1 +CCc1nc2c(N(C)C)c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 +CN1CCC(c2cc3c(-c4cccc(NCCCc5ccccc5)n4)ccnc3[nH]2)CC1 +COC(=O)CCc1c(C)[nH]c(C=C2C(=O)Nc3cc(-c4ccc(O)c(OC)c4)ccc32)c1C +O=C(Nc1nc(-c2cccc(Br)c2)cs1)c1ccc(Nc2ccncn2)cc1 +CC(C)(C)C(=O)OCC1(CO)CC(=Cc2ccc(OC(F)(F)F)cc2)C(=O)O1 +Cc1ccc2[nH]c(-n3[nH]c(C)c(Cc4ccc(F)cc4)c3=O)nc2c1 +NC(=NO)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CCNc1nc2sc(-c3cccc(C(C)NC(=O)C4CCN(C)CC4)c3)nc2c2c1ncn2C +CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1C(=O)c1ccccc1 +COCCCCn1cnc2cc(NCc3ccc(Cl)c(Cl)c3)[nH]c(=O)c21 +CN1CCC(c2ccc(-c3cc4ncn(C)c(=O)c4c(N4CCC(CO)C4)n3)cc2F)CC1 +CCn1c(=O)c2nc(-c3ccc(N(C)C)cc3)[nH]c2n(CC)c1=O +Cc1cn(-c2ccc3n(c2=O)CCN(CCOc2ccccc2-c2csc(C)n2)C3=O)cn1 +CC(=O)NCCc1ccccc1-c1onc(C2CNCCC2(OCC(O)CO)c2ccc(F)c(F)c2)c1Br +CCOc1ccc(-n2c(C)c3c(C)nnc(N(C)C)c3c2C)cc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2ccon2)CC1 +CCCN(CCN1CCN(c2cccc3ccccc23)CC1)C1CCc2ccc(O)cc2C1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3cccc(F)c3)cc2)cc1)C(=O)O +Fc1ccc(OCCCN2CCCN(c3ccc(Cl)cc3)CC2)cc1 +O=C(CN1C(=O)CCc2ncccc21)Nc1scc(Br)c1-c1ncco1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1NC(=O)c1cccc2c(N)nccc12 +CCn1c(-c2nonc2N)nc2cnc(Oc3cccc(NC(=O)c4ccc(OCCN(C)C)cc4)c3)cc21 +CC(NS(C)(=O)=O)c1ccc(CN2CCOC(c3cccc(C(F)(F)F)c3)C2)cc1 +CC(=O)N(C)C1CC2CCCCC2C1C=Cc1ccc(-c2cccc(F)c2)cn1 +N=C(N)c1ccc(Cc2ccc(-c3ccc(C(=N)N)nc3)o2)cc1 +CCOC(Cc1ccc2c(ccn2Cc2nc(-c3ccc(F)c(C)c3)oc2C)c1)C(=O)O +O=C(Nc1ccc(Oc2ccncc2-c2cccnc2)c(F)c1)C1=NN(c2ccc(F)c(F)c2)c2ccccc2S1(=O)=O +Cc1ccc(-c2nn(-c3ccc(S(N)(=O)=O)cc3)cc2C(=O)NN)cc1 +CN(CC=Cc1ccc(C(F)(F)F)cc1)Cc1cccc2[nH]ccc12 +c1ccc(C(CCNC2=NCCCCCN2)c2ccccc2)cc1 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+CCCCCCc1cc(O)c2c(c1)OC(C)(C)C1=C2CCN(C)C1 +Cn1nc(-c2ccccc2F)cc1-c1ccc(C(=O)Nc2ncc(Cl)cc2F)s1 +CC(C)c1cccc(C(C)C)c1NC(=O)C1c2ccccc2COc2cc(Br)ccc21 +COc1ccc2nc(NCCCNC(=O)Nc3ccccc3)c3c4ccccc4[nH]c3c2c1 +CC1CN(CC(Cc2ccccc2)C(=O)NC(CCCN)C(=O)O)CCC1(C)c1cccc(O)c1 +O=C(O)c1cccc(-n2cccc2C=C2NC(=O)N(c3ccc(Cl)cc3)C2=O)c1 +O=C(NC(Cc1ccccc1)C(=O)NC(COCc1ccccc1)C(=O)O)C(S)Cc1ccccc1 +CC1CN(CC2CCOCC2)CCN1C(=O)N1Cc2c(NC(=O)c3cn(C)cn3)n[nH]c2C1(C)C +Cc1nn(C2CCOCC2)c2sc(C(=O)NC3CCC(N4CCNC(=O)C4)CC3)cc12 +Cc1cccc(C(=O)N2CCC(O)(c3ccccc3)C3CCCCC32)n1 +COc1nc(C)c(Nc2nc(Cl)cn(C(CCF)C3CC3)c2=O)c(OC)n1 +O=C(NCCNCc1ccc2ccccc2c1)c1ccc2nc(NC(=O)C3CCCCC3)sc2c1 +Cc1cc(OCC2CN(C)c3ccccc3O2)ccc1C(=O)Nc1cccc(CC(=O)O)c1C +COc1cc(Br)ccc1OCCNC(C)Cc1cc(C(N)=O)c2c(ccn2CCCO)c1 +Cc1cc(Oc2cc(NC(=O)C3CC3)ncn2)c(F)cc1NC(=O)Nc1ccc(Cl)c(C(C)(F)F)c1 +COc1cc2nccc(Oc3ccc(NC(=O)Nc4cccc(Cl)c4Cl)cc3)c2cc1OC +CC(C)CC(NC(=O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O)C(=O)O +CCCCOc1ccc2c(c1)C13CCCCC1C(C2)N(C)CC3 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+COc1cc(C(F)(F)F)ccc1-c1cccc2c1C(C)CN(S(=O)(=O)Nc1ncns1)C2 +O=C(O)CNc1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCC2)c1=O +CNc1cccc(CCOc2ccc(C3CC3CC(=O)O)cc2)n1 +O=C(c1ccc(O)cc1OCC(O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CC(O)CO1 +CSc1nn2cc(-c3nc4cc(OC(F)(F)F)ccc4o3)nc2s1 +CCOC(=O)COc1cccc2ccc(Cc3cnc(COC)c4cc(OC)c(OC)cc34)nc12 +OCC1OC(Oc2ccc(-c3ccccc3)cc2Cl)C(O)C(O)C1O +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3ccnc4ccccc34)cc2)cc1)C(=O)O +Cc1c(C)n(Cc2ccccc2)c2ncnc(OC3CCN(Cc4cscn4)CC3)c12 +O=S1(=O)N=C(NC(CCCO)c2ccccc2)OC2CCCCC21 +Cc1cc(Cl)ccc1COc1ccc(S(=O)(=O)N2CCCC(C)(O)C2C(=O)NO)cc1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC#Cc4ccccc4C(=O)OCC)c3)nc2n(CCC)c1=O +CC(OCC(N)c1ccccc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +NCc1cc(F)ccc1CN(Cc1nc2ccccc2[nH]1)C1CCCc2cccnc21 +CCc1ccn2cc(-c3cc(-c4ccccc4)no3)nc2c1 +CCOc1ccc(Cl)cc1-c1cc(N)nc(Nc2ccc(CO)cc2)c1 +O=C(O)c1nc2ccc(I)cc2c2[nH]c3c(Cl)cccc3c12 +N#Cc1cc(-c2ccnc(N)n2)ccc1OCc1ccc(F)cc1 +CCN(CC)c1nc(Cl)nc(Nc2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)n1 +OC1CCCN(c2cccc(-c3n[nH]c4cnc(-c5cccnc5)cc34)n2)C1 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+CCOC(=O)N1CCCC2C(C=Cc3ccc(-c4cccc(C#N)c4)cn3)C3C(C)OC(=O)C3CC21 +CN(C)C(=O)Nc1ccc(Cn2[nH]c(=O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)cc1 +COc1ccc(C(=O)C=Cc2ccc(C=CC(=O)c3ccc(OC)c(OC)c3)cc2)cc1OC +Cc1cc(NC(=O)Nc2ccc(-c3cc(NC(=O)c4ccc(N5CCN(C)CC5)cc4)[nH]n3)cc2C)no1 +CN(C)CCNc1ccn2ncc(-c3ccc4ccccc4c3)c2n1 +Nc1nc(N)c2nc(CN3c4ccccc4Cc4ccccc43)cnc2n1 +CCCOc1ncc(C(C)=O)cc1-c1nc(O)c2nn(C3CN(C)C3)c(CCC)c2n1 +CCNC(=O)CNc1ncnc2c1c(-c1ccccc1)cn2C1OC(C)C(O)C1O +COc1ccc2[nH]c(CN3CCc4ccccc4C3)c(CCNC(C)=O)c2c1 +CCn1c(=O)c2c(nc3ccccn32)n(Cc2ccccc2)c1=O +C(#Cc1ccc(CN2CCCCC2)cc1)CCN1CCOCC1 +Cc1n[nH]c(C)c1CC(=O)NCc1ccc(Cl)cc1Cl +O=C(CCCCCCNC(=O)c1ccc(N(c2cccc(Cl)c2)c2cccc(Cl)c2)cc1)NO +Cc1cc(CN2CCCC2CNc2nc(N)n3nc(-c4ccco4)nc3n2)no1 +O=C(O)C1CCCN(CCC=C(c2sccc2COCc2ccccc2)c2sccc2COCc2ccccc2)C1 +O=C(Nc1cc(-c2c(-c3ccc(F)cc3)nc3n2CCS3)ccn1)c1ccccc1 +COc1cc(C)c2nc3[nH]nc(C)c3c(C(O)c3cncs3)c2c1 +O=C(O)Cc1cc(Br)c(N(Cc2ccc(Oc3ccccc3)cc2)Cc2cccc(F)c2)c(Br)c1 +CC1CN(c2ccc(C(N)=O)cc2)CCN1c1cccc(C(=O)NC2C3CC4CC2CC(O)(C4)C3)n1 +CCC1CN(C2CCN(C(=O)c3ccc4ncccc4c3)CC2)CCC1Cc1ccc(Cl)c(Cl)c1 +CCCCCc1ccc(S(=O)(=O)NCCc2c(-c3ccc(OC)cc3)n[nH]c2CC(C)C)cc1 +c1cc(-c2ccc(OCCCN3CCCCC3)cc2)ccc1CN1CCCCC1 +COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(C#N)c1Cc1ccc(-n2cccn2)cc1 +O=C(NCc1cccnn1)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +N#Cc1cc(C23COC(CF)CC2CSC(N)=N3)c(F)cc1F +CN1CCc2nc(NC(=O)c3cccc(CNC(=O)c4ccc5cc(O)ccc5c4)c3)sc2C1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CCN(c5ccc(OC)cc5)C4)c3)nc2n(CCC)c1=O +Cc1ncn(C2=NCC(=O)N3CCc4c(cccc4C4CCC4)C3=C2)n1 +CN1CCN(c2nc(N)nc(Cc3ccc(Cl)c(Cl)c3)n2)CC1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccccc3)n(CCN3CCOCC3)c2c1 +O=C(O)COc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +COc1cccc(Cl)c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)cc1 +CCS(=O)(=O)CC(CC1CCCCC1)NCc1ccc(C(=O)NC(CCSC)C(=O)O)c(-c2ccccc2C)c1 +COc1ccc(C(Cc2ccccc2)NCC(O)CCc2ccc(O)c(NS(C)(=O)=O)c2)cc1OC +COc1ncccc1-c1cncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1 +CC(=O)OCC(=O)C1C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3=CCC21C +CCCC(NC(C(=O)NO)C(C)O)c1ccc(C#Cc2ccccc2)cc1 +CC(C)C(C)NC1=NS(=O)(=O)c2sc(Cl)cc2N1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(C(=O)NC2CCCCC2)c(Cl)c1 +CCCCCCCC(=O)OCCCC1(CO)CC(=CCC(C(C)C)C(C)C)C(=O)O1 +c1cncc(-c2cc3c(-c4cnn(C5CCNCC5)c4)n[nH]c3cn2)c1 +CS(=O)(=O)CN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21 +Nc1ccc2c(c1)CC(NCC1CCN(CCNS(=O)(=O)c3cccc4ccccc34)CC1)CCC2 +c1csc(-c2ccc3c(-c4cc5cc(CN6CCCCC6)ccc5[nH]4)n[nH]c3c2)n1 +CC[N+](CC)(CC)CCCCCCCC[N+](CC)(CC)CC +Cn1cc(C#N)c2ccc(Nc3ncc(-c4cccc(CN)c4)o3)cc21 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCCC2)CCN(C2CCCC2)C1 +CNc1nc(Nc2ccc(C(=O)N3CCC(O)CC3)cc2OC)ncc1F +CCCOc1sc(C(=O)N2CCC(c3cccc(CN)c3)CC2)c(C)c1Br +COC(=O)c1c[nH]c2cc(CN3CCN(Cc4ccc(OC)cc4)CC3)c(C)cc2c1=O +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)c2cccc(Br)c2)CCC3(O)C1C5 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(SC)cc2)C1O +c1ccc(COCC2CCCCC23OOC2(CCCCC2COCc2ccccc2)OO3)cc1 +Cc1c(F)cc(C(=O)NC2COC2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CCc1nn(Cc2c(Cl)cccc2Cl)c2cc(CC(=O)O)ccc12 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+CC(C)CCN1C(=O)C(NC(=O)Nc2ccccc2)C(=O)N(Cc2ccccc2)c2ccccc21 +CN(C)CCCNc1nc(NN=Cc2ccc(Cl)cc2)nc2ccccc12 +Nc1ncc(-c2ccc(C3(c4noc(-c5cccc(S(N)(=O)=O)c5)n4)CCC3)cn2)cn1 +O=C(c1cccc(F)c1)N1CCC(F)(F)C(Oc2ccc3ccccc3n2)C1 +CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CN(C(=O)OC(C)(C)C)CC3)cc1 +O=C(NC1CCCCC1)N1CC(Cc2ccccc2)C(c2ccccc2)=N1 +COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3c3cccc(NC(C)=O)c3)ccc2[nH]1 +O=C(NCc1ccc(S(=O)(=O)N2CCN(C3CCOCC3)CC2)cn1)N1Cc2ccncc2C1 +Cc1cn2cc(-c3cccc(O)c3)nc(N3CCOCC3)c2n1 +CN(C(=O)Cc1c[nH]c2ccc(C(=N)N)cc12)c1ccc(-c2ccccc2S(N)(=O)=O)cc1 +O=C(c1ccc(F)cc1F)N1CCn2c(cnc2-c2ccc(F)cc2F)C1 +CC(C)C12OC1C1OC13C1(C)CCC4=C(COC4=O)C1CC1OC13C2(O)CNc1ccc2c(cnn2C)c1 +Fc1cccc(F)c1-c1ccc2[nH]nc(-c3cncc(OC4CCCNC4)n3)c2c1 +Cc1c2c(n3c1CCN(C(=O)CO)CC(C)C(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +CCn1c(C)cc(C=C2NC(=O)N(c3ccccc3)C2=O)c1C +CC1Cc2cccc3c2N1C(=O)C(N1CCN(Cc2ccc(Cl)cc2)CC1)CC3 +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1NCC1CCN(C)CC1 +CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cc(F)cc(F)c5)cc34)c(Nc3ccccc3)c2)CC1 +CC(NC(=O)C(=O)c1c[nH]c2ccc(Cl)cc12)c1ccc([N+](=O)[O-])cc1 +COc1cc(N2CCC(N)CC2)ccc1-c1nc2c(C)nn(C3CCCCC3)c(=O)c2[nH]1 +CC(C)(O)C1CCC(NC(=O)c2cnc(-n3ncc4cc(Cl)cnc43)cc2NC2COC2)CC1 +Cc1ccc(CC2C(c3ccc(C)cc3)CC3CCC2N3C)cc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)NCCN=C(S)Nc4cccc(N=C=S)c4)cc3)[nH]c2n(CCC)c1=O +Cc1n[nH]c(=O)n(CCCN2CCN(c3ccccc3OCC(F)(F)F)CC2)c1=O +O=C(NCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C1CCC(N2CCC(c3ccccc3)CC2)C1 +CN(C)CCCn1cc(NC(=O)c2ccc3cc4n(c3c2)CCCNC4=O)cn1 +O=C(NO)C1Cc2nccnc2CN1S(=O)(=O)c1ccc(Oc2ccncc2)cc1 +NC(=O)c1cc2c(-c3ccc(Br)c(F)c3F)cncc2s1 +COc1ccc2c(c1)CCN(CCCCc1ccccc1)CC2O +CCc1cccc2c(=O)n(C3CN4CCC3CC4)ccc12 +Cc1cnc(N2CC3CCN(C(=O)c4ccccc4-n4nccn4)CC32)cn1 +Cc1c[nH]c(=O)n(CCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O +CC1(C)CC2(CCCN(C3CCN(C(=O)c4c(N)sc5ccccc45)CC3)C2)C(=O)O1 +O=C(NCC#CCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2 +CC(NC(=O)c1ccco1)C(=O)N1CCCN(CCCOc2ccc(-c3noc(C(C)C)n3)c(F)c2)CC1 +COc1ccc2[nH]cc(CCCCN3CC=C(c4ccc5c(c4)OCO5)CC3)c2c1 +Cc1sc(NC(=O)c2ccco2)c(C(c2cccnc2)N2CCC(C)CC2)c1C +CC1=NC2(N=C1N)c1cc(-c3cc(Cl)cc(C#N)c3)ccc1CC21CCC(O)CC1 +Cc1cc(OC(CCC(F)(F)F)c2ccc(C(=O)NCc3nnn[nH]3)cc2)cc(C)c1-c1ccc(C(C)(C)C)cc1 +c1ccc(NCCCCCCCCCCCCNc2c3c(nc4ccccc24)CCCC3)cc1 +Cc1ccc(S(=O)(=O)N2CCNC(=O)C2CC(=O)NC2CCCc3cc(CNC(C)(C)C)ccc32)cc1 +Cc1cccc(N2CCC(C)(c3ccccc3)OC2=O)c1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CNCC(O)C(Cc1ccccc1)NC(=O)C(O)C(F)(F)F +CCCCn1c(=O)[nH]c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C(=O)OC)cc4)cc3)nc2c1=O +CCOc1ccc(C=CCN(C)Cc2cccc3cc[nH]c23)cc1 +Fc1ccccc1Nc1ncnc2ccc(-c3cncs3)cc12 +O=C(NCC1(O)CCCCCC1)c1cc(-c2ccc(CO)cn2)ccc1Cl +O=C(Nc1ccc(Cl)cc1)c1cc(Br)cnc1NCc1ccncc1 +Cn1ccc(COc2ccc3nc(CC4(C(=O)O)CCCC4)n(Cc4ccc(Br)cc4)c3c2)n1 +CC(NC(=O)c1ccc2c(ccn2Cc2ccc(F)cc2F)c1)c1ccc(Br)cc1 +CCC1CC(C(=O)NCC2CCCO2)CN(Cc2nc(-c3ccncn3)[nH]c2C)C1 +O=C(NO)C1c2ccc(O)cc2CCN1S(=O)(=O)c1cc(Cl)ccc1Cl +COc1ccccc1COCCCOc1ccc(N2C(=O)CNCC2COCc2ccc(F)c(C)c2)cc1 +CCN(CC)CCCNc1nc(-c2ccc(NC(=O)Nc3ccccc3Cl)cc2)nc2c(Cl)c(Cl)sc12 +OC1c2ccc(F)cc2CC1N1CCN(c2cc(Cl)cc3c2OCCO3)CC1 +CC(C)C(O)CC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2ccccc2o1 +COc1ccc(-c2nc(C)c(Cl)c(NCC(NC(=O)CCCN3CCNCC3)c3ccccc3)n2)nc1 +CCCN(CCOC)c1nc(C)nc2c1c(C)nn2-c1ccc(OC)nc1C +CCC(=O)NCC1CC1c1cccc2oc(CCCCc3ccccc3)cc12 +Cc1ccc(C(O)(c2ccc(Cl)cc2)c2cncnc2)cc1 +O=C1C(=Nc2cccc(C(F)(F)F)c2)c2ccccc2N1c1cccc(OCCCN2CCCC2)c1 +Cc1ccc(S(=O)(=O)c2coc(S(N)(=O)=O)c2)cc1 +Cn1ncc(-c2nn(C)c3ncnc(N4CC(F)C4)c23)c1-c1ccc(C(F)(F)F)cc1 +CC(C)NCC(=O)N1CC=CCCOc2cccc(c2)-c2ccnc(n2)Nc2cccc(c2)C1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2ccc(OCc3ccccc3)cc12 +Cc1n[nH]c2cnc(-c3cncc(OCC(N)Cc4ccc(F)c(F)c4F)c3)cc12 +CC(NC(=O)c1ccc(C#Cc2cccc(F)c2)nc1)C(C)(C)O +O=C(Nc1ccc(Cl)cc1)Nc1cccc(-c2ccccn2)c1 +Cn1ccc2cc(C(=O)NCCCCCC(=O)Nc3ccccc3N)ccc21 +CC(=O)NC(=Cc1ccco1)C(=O)NC(C(=O)NC(C=C(C)C(=O)O)C(C)C)C(C)(C)C +CCOc1cc(C(c2c(C)n[nH]c2O)c2c(C)n[nH]c2O)ccc1O +Cc1c(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)cccc1C(=O)O +Cc1cccc(Cl)c1Nc1nc2c(N)cccc2n2cncc12 +O=C1c2cc(Cl)cc(Cl)c2OC2c3[nH]c4ccc(O)cc4c3CCN12 +O=C1CC(c2ccccc2)=NCC2(CN3CCC2CC3)N1 +COc1ccc(Cn2c(Nc3ccc(Oc4ncccc4C4CCOCC4)cc3)nc3ccccc32)cc1 +CSc1ccc(-c2cn(C)nc2C2CCC(F)(F)CC2C(=O)NCC#N)cc1 +CC(C)CC(NC(=O)CC(NC(=O)c1ccccc1)c1ccccc1)B(O)O +Cc1c(CC(=O)OCCO)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1cccc(F)c1 +CC(C)C(=O)NCc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2N)cc1 +COc1cccc(-c2ccc(CNC(=O)Nc3cccc(Cl)c3Cl)c3cnccc23)c1 +Cc1c(C2(N(C)C)CCC(c3ccccc3)(N(C)C)CC2)[nH]c2ccccc12 +O=C(CCCCCCc1ccccc1)c1ncc(-c2ccco2)o1 +CCC(N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1)C(C)(O)C(F)(F)F +CC(Cl)(Cl)C(NC(=O)c1ccc(Br)cc1)NC(=NC#N)Nc1ccc(Cl)nc1 +NCCCCC(NC(=O)C(CCC(=O)O)NC(=O)CCc1ccc(-c2ccccc2)cc1)C(N)=O +CC(=O)Nc1nc(C)c(-c2ccc(-n3cccn3)cc2)s1 +Cc1cc(Nc2ncc(Cl)c(Nc3cn(C)nc3S(=O)(=O)C3CC3)n2)c(OC(C)C)cc1C1CCNCC1 +CC(C)(N)C(=O)NC(Cc1c[nH]c2ccccc12)c1nnc(CCc2c[nH]c3ccccc23)n1-c1ccccc1 +COc1ccc(CNC2CCN(S(=O)(=O)CCC3CCc4ccccc4N3S(=O)(=O)c3ccc(OC)cc3OC)CC2)cc1 +O=C(NCC(=O)N1CCCC1)Nc1ccc2cnc(F)cc2c1 +CCc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3ccnc3)c1)=N2 +N#CSCC1CC(O)(c2ccccc2)C(c2ccccc2)C(c2ccc(Cl)cc2)O1 +O=C(NN=Cc1ccc(-c2ccc([N+](=O)[O-])cc2)o1)C1COc2ccccc2O1 +CC(=O)CCCC(=O)Nc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +Cc1c(C=CCN(C)Cc2ccccc2)nc(O)c2c1ccc1nc(Nc3c(Cl)cccc3Cl)n(C)c12 +CNC(C(=O)NC(C(=O)N(C)C(C=C(C)C(=O)O)C(C)C)C(C)C)C(C)(C)c1cn(C)c2ccccc12 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=NC#N)OC2CCCC2)CC1 +O=C(NC1CCCNC1)c1ccnc2nc(-c3ccc(Cl)cc3)[nH]c12 +N#Cc1c(N)nc(N)nc1NC(CC1CC1)c1nc2cccc(Cl)c2c(=O)n1-c1cccnc1 +OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1ncc[nH]1 +CCCc1ccc(-c2oc(COc3ccc(OCC(=O)O)c(C)c3)nc2-c2ccc(OC)cc2)cc1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)NC(CCCCN)C(N)=O)cc1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCN(C(C)C)CC2)cn1 +COc1ccc(-c2cc(=O)n(CC=Cc3ccccc3)nc2-c2ccc(OC)cc2)cc1 +Cc1ncnc(C)c1OCC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12 +O=S(=O)(c1ccc(C(F)(F)F)nc1)N1C2Cc3[nH]ncc3C1CC(c1ccccc1)C2 +O=C1NCN(c2ccccc2)C12CCN(C1CCc3c(Cl)ccc(Cl)c3C1)CC2 +O=c1[nH]c(C2CCC2c2csc(Cl)n2)nc2c1cnn2C1CCC(F)(F)CC1 +CC(=O)N1N=C(c2cc(F)ccc2F)SC12CCOc1ccccc12 +Cc1cccc(NC(=O)Nc2ccc(-c3cncc4[nH]nc(N)c34)cc2)c1 +COCC(C)Oc1ccc2[nH]nc(-c3cc(N4CCOC(C(F)(F)F)C4)ncn3)c2c1 +CNc1nc(Cl)nc2c1ncn2C1OC(C(=O)NCCC(C)C)C(O)C1O +COc1ccccc1N(C)c1cnc2nc(N)nc(N)c2c1 +O=C(O)C(CCCN1C(=O)c2ccccc2C1=O)S(=O)(=O)c1ccc(-c2ccc(Cl)cc2)cc1 +Cc1c(OCC2CN(C)c3ccccc3O2)ccc(C(=O)n2c(C)c(CC(=O)O)c3ccccc32)c1C +O=C(Nc1cn(CC(=O)N2CC3CN(CC4CCC4)CC3C2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +COCC(N)C(C)Nc1nnc(C(N)=O)c(Nc2cc(C)c3nn(C(C)(C)C)cc3c2)n1 +CCCCc1nc2cc(OC)cc(C(=O)O)c2n1Cc1ccc(N(CC)C(C(=O)O)c2ccccc2)cc1 +CC(=O)N1CCN(c2cccc(-c3cc(-c4ccnn4C4CCOCC4)c4c(N)ncnn34)c2)CC1 +O=C(C=Cc1ccc2c(c1)nc(CCc1ccccc1)n2CCN1CCOCC1)NO +O=C(NCC(NS(=O)(=O)c1c(Cl)cccc1Cl)C(=O)O)c1ccccc1 +COc1ccc(CN2CCN(CCOc3ccc(C(=O)NC(=N)N)cc3NC(=O)c3ccc(Cl)cc3Cl)CC2)c(OC)c1OC +O=C(O)c1ccc(Sc2ccc(CN3CCC(N4C(=O)N(C5CCOCC5)CC4c4ccccc4)CC3)cn2)cc1 +Cn1c(-c2ccc(-c3cnc(O)nc3)cc2)nnc1C1(c2ccc(Cl)cc2)CCC1 +O=C(O)Cc1nn(Cc2nc3cc(F)cc(F)c3s2)c2ccccc12 +c1ccc2c(c1)CCC(CNCCCCNC1=NCCCN1)O2 +O=C(CCN1CCCCC1)NC(Cc1c[nH]c2ccccc12)C(=O)CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CS(=O)(=O)Nc1cccc(C(O)CNCCOc2ccc3c(Cl)n[nH]c3c2)c1 +Cc1ncsc1-c1nnc(SCCCN2CCC3(CC3c3ccc(C(F)(F)F)cc3)C2)n1C +c1cn(-c2cncc(-c3cnc(Nc4cc(N5CCOCC5)ccn4)s3)c2)nn1 +CC(C)c1ccc(CCCN2CC=C(CCC(=O)NO)C2=O)cc1 +NS(=O)(=O)c1ccc(NC(=O)CNCCNCC(=O)O)c(I)c1 +CC(C)c1cccc(C(C)C)c1OC(=O)NC(=O)SC1CCCCC1 +COCCN1CCC(Nc2nc(-c3nc4ccccc4n3C(C)c3ccccc3)cn3c(C)nnc23)CC1 +Cc1ccc(-c2ccn(-c3ccc4c(cnn4CCN4CCCC4)c3)c(=O)c2)cc1 +COc1ccc(-c2cccc(CNC(=O)c3ccc4c(c3)OCO4)c2)cc1CN1CCNCC1 +COC1C(=O)N2C(C(=O)OCc3ccc(C(=O)OC(C)(C)C)cc3)=C(COC(C)=O)CS(=O)(=O)C12 +CN1CCCC1Cc1cn(S(=O)(=O)c2ccccc2)c2ccc(Cl)cc12 +O=C(N1CCC(c2cc(F)ccc2F)(S(=O)(=O)c2ccc(Cl)cc2)CC1)C1(C(F)(F)F)CCCCC1 +COCCn1cc(-c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)cn1 +CN(C(=O)c1ccc(N(C)C2CCN(c3ncnc4[nH]ccc34)C2)nc1)c1ccccc1 +O=C(O)COc1ccc(F)c(NCc2cc(-c3cccc(F)c3)ccc2F)c1F +CC(C)c1sc(CO)c(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +O=c1c2sc(-c3ccc(Cl)cc3)cc2ncn1-c1ccc2sc(CN3CCCC3)cc2c1 +Cc1nnc(N2CCCC2)c2nn(-c3ccc(Cl)cc3OC(F)(F)F)c(C)c12 +Cc1cc(-c2nnn(Cc3ccc(C(=O)O)cc3)n2)cc(C(=O)NCc2ccccc2)n1 +COc1cc(Nc2nc3ccccc3nc2S(=O)(=O)c2ccccc2)cc(OC)c1 +CCCCCCCCCCCCCCCCCCOCCOP(=O)(O)COC(COC)Cn1cnc2c(N)ncnc21 +CC(C)N1CCC(O)(c2cncc(CNc3cc(Cl)c4ncc(C#N)c(Nc5ccc(F)c(Cl)c5)c4c3)c2)CC1 +COC(=O)C1C2CCC(CC1OC(c1ccc(F)cc1)c1ccc(F)cc1)N2 +CCN(CC)CCCCC(CCCCN(CC)CC)Oc1ccnc2cc(Cl)ccc12 +CN1CCN(c2nc3ccccc3c(-c3ccccc3)c2CCO)CC1 +Cc1nc2cc(-n3ncc(C(=O)c4cc5ccc(C6CCN(C)CC6)cc5[nH]4)c3N)ccc2[nH]1 +O=C(NCC(NS(=O)(=O)c1cccnc1)C(=O)O)c1cc2cc(CCC3CCNCC3)sc2s1 +N#Cc1cnn2c(Nc3ccc4c(c3)CCC(=O)N4)cc(N3CCCC3CC(=O)O)nc12 +CCCc1nc(C(=O)NCCCN2CCN(c3cccc(Cl)c3C)CC2)cn1-c1ccc(Cl)cc1 +NC(CCc1ccccc1)C(O)C(=O)NNc1cccc2ccccc12 +Clc1ccc(-c2nc(CNC3CCCC3)cn2-c2ccc(Cl)cc2Cl)cc1 +CC1C(=O)NN=C2COc3cc(F)c(NC4CNC4)cc3N21 +Cc1cccc(-c2c3c(=O)n(C)c(=O)n(C)c3c3n2CC(C)OC3c2ccc(Cl)o2)c1 +CC(C)C#Cc1cccc(C2(c3ccc(OC(F)F)cc3)N=C(N)N(C)C2=O)c1 +[C-]#[N+]c1cc(-c2ccnc(Nc3ccn(C4CCNCC4)n3)c2)ccc1OCC1CC1 +COc1ccc(-n2c(CCc3cn(C(=O)OC(C)(C)C)c4ccccc34)nc3ccccc3c2=O)cc1 +COc1ccc(-c2ccc(C(=O)N3Cc4c(nc5ccccc5c4O)C3c3ccc4c(c3)OCO4)o2)cc1 +CCN(CC)C(=O)C1Sc2c(OC)cccc2-c2c1c1ccccc1n2CCF +CCCn1c(=O)c2nc(C(C3CC3)C3CC3)[nH]c2n(CCC)c1=S +CCCCC(=O)NC1CCCc2c1c1cc(OC)ccc1n2C +N#CC1CC2CC2N1C(=O)C(N)C12CC3CC(CC(F)(C3)C1)C2 +COCCCn1cc(Nc2cc(-c3ccc(OC4CCOCC4)c(C#N)c3)ccn2)cn1 +O=c1c(NCC2CCOCC2)nc2ccc(-c3cnc(O)nc3)nc2n1CC1CCCCC1 +CCCC(=O)Nc1n[nH]c2cc(-c3ccc(O)cc3)c(Br)cc12 +CCCCN(CC)C(=O)C(=O)c1c(-c2ccccc2)n(C)c2ccccc12 +C#Cc1ccc2c(c1)C(=O)N1CCC1c1c(C(=O)OCC)ncn1-2 +CC(NS(=O)(=O)c1ccccc1Cl)C(Cc1ccc(Cl)cc1)c1cccc(C#N)c1 +Cc1ccc(Nc2ncc(C(NC(=O)c3nccs3)C(C)C)cc2Cl)cn1 +O=C(C[S+]([O-])C(c1ccc(Br)cc1)c1ccc(Br)cc1)NCCCc1ccccc1 +Cc1ccc(CN2CCC(N3CCC(c4ccc(O)c(F)c4)C(F)C3)C2=O)cc1 +CCc1ccc(-c2nc(C(N)=O)c(-c3ccc(N4CCNC(C)(C)C4)cc3)o2)c2cc[nH]c12 +CCCCS(=O)(=O)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +COc1ccc(C2C(C(=O)O)C(c3ccc4c(c3)OCO4)CN2CC(=O)NC2CCCC2)cc1 +Fc1ccc2[nH]cc(CCCNCCOc3cccc4c3OCC4)c2c1 +O=C(NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1)c1ccc(C(F)(F)F)cc1 +COc1cc(OC2CN(C(=O)c3nnc(-c4ccc(C(F)F)cc4)o3)C2)ccc1CN1CCCC12COC2 +CC(C)CCNC(=O)C(c1cccnc1)N(Cc1ccccc1)C(=O)Cn1nnc2ccccc21 +C=C(CCC12OC(C(=O)O)C(O)(C(=O)O)C(C(=O)O)(O1)C(O)C2O)C(OCC)C(C)Cc1ccccc1 +Cc1nccc2nc(NC3CC3)c(N3CCC(C(F)c4ccc(F)cc4F)CC3)nc12 +c1cc2cc(CCCCc3cc4ccc(C5=NCCN5)cc4o3)oc2cc1C1=NCCN1 +Nc1ccc2c(c1)oc1c(N3CCOCC3)c(F)cc3c(=O)c(C(=O)O)cn2c13 +CC(F)(F)CC(NC(=O)N1CCC2(CCCC2)CC1)C(=O)NC1(C#N)CC1 +NC(=O)c1nn(CC(=O)N2C(C(=O)NCC(F)F)CC3CC32)c2ccccc12 +O=C(Nc1ccccc1C(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC1CCOC1)OCc1ccccn1 +COc1cc(OC)cc(Oc2cnccc2-c2n[nH]c(Nc3ccc4c(c3)OCCO4)n2)c1 +COc1ccc(Cl)cc1Nc1nc(-c2sc(NC(=O)c3ccccc3)nc2C)cs1 +CN(C)CCN1CCN(C(=NS(=O)(=O)c2ccc(Cl)cc2)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)CC1 +COC(=O)Nc1nc2ccc(C(=O)c3ccccc3C(=O)Nc3cccc(I)c3)cc2[nH]1 +Cc1cc(-c2nnc(NCC3OCCO3)o2)nc2c(C(C)(C)C)cc(NCC(F)(F)F)cc12 +Cc1cc(C(C)C)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +Nc1nccn2c(C3CCC4COC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3F)c12 +Cc1c[nH]c2ncnc(N3CCC(O)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12 +CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2C)cc1 +CC(C)C(=O)NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1 +COCC(=O)Nc1ccc2c(-c3cc4ccc(C)cc4[nH]3)n[nH]c2c1 +CSc1cccc(NC(=O)NC2C(=O)N(CCC(C)C)c3ccccc3N(c3ccccc3F)C2=O)c1 +CC(=O)Nc1ccc(-c2ccc(C(O)(c3c[nH]cn3)C(C)C)cc2)cc1 +CC(C)Oc1cccc(Nc2nc3cc(-c4nnn[nH]4)ccc3c3sccc23)c1 +CC(C)C1OC(=O)C1NC(=O)OCc1ccc(-c2ccccc2)cc1 +CC(C(=O)NO)N1CCNc2cc(Oc3cccc([N+](=O)[O-])c3)ccc2S1 +NC(CC(=O)N1CCn2nc(C(F)(F)F)nc2C1C(F)C1CC1)Cc1cc(F)c(F)cc1F +COC12CCC3(CC1C(C)(O)CCC1CCCC1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CCC(c1ccc(Cl)c(Cl)c1)n1c(S)nc(C(N)=O)c1C#N +CN1C(=O)C(NC(=O)c2cc3cc(F)ccc3[nH]2)Cc2ccccc21 +O=C(CC12CC3CC(C1)CC(C1CCCC1)(C3)C2)NN=Cc1ccc([N+](=O)[O-])o1 +Fc1cc(-c2ccccn2)cc(-n2nnc(-c3ccccn3)n2)c1 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2ccc(C(F)(F)F)cc2)cc1 +CCNc1nc(Cl)nc2c1ncn2C12CC(O)C(O)C1C2 +CC#CCNc1ccc(S(=O)(=O)CC2(C(=O)NO)CCCN(S(=O)(=O)C(C)C)C2)cc1 +CNc1cc(-c2cccnc2Nc2c(C)ccc3c(Nc4ccc(Cl)cc4)nccc23)ncn1 +Cc1cc(Oc2cncnc2)cc(C(=O)Nc2cccc(F)n2)n1 +CN1CCc2cc(OCCOCCO)cc3c2C1Cc1ccc(O)c(O)c1-3 +CCC(Cc1ccc(N2CCC(C(=O)NCc3ccccc3C(F)(F)F)CC2)cc1)C(=O)O +CC(C)(C)C(CO)NCc1nc(-c2ccc(C(F)(F)F)cc2)ccc1F +CC(C)(CO)NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +Cc1nc(-c2ccccc2)c(C(=O)N2CCCC(C)C2CNC(=O)c2cccc3cccnc23)s1 +CCC(NC)C(=O)NC1C(=O)N2C(CCC1CCN)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +CC(=O)Nc1nc(C)c(S(=O)(=O)Nc2ccc(C(O)(C(F)(F)F)C(F)(F)F)cc2)s1 +O=C(Cc1ccccc1)NC1CCCc2c1[nH]c1ccc(Br)cc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CN(C(=O)OCCCc2cccnc2)C1 +NC(CC(=O)Nc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1)C(=O)O +O=C(c1ccccc1)N1CCOc2ccc(-c3cnc4ccccc4c3)cc2C1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCCc5nc(-n6cnnn6)ccc54)CC3CO2)c1C +O=C(CC1CCN(C(=O)Oc2ccccc2)CC1)N1CCN(C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +CCc1c(C)[nH]c(=O)c(N(C)CCOC)c1Cc1cc(C)cc(C)c1 +CCN(CC)C(=O)C1(c2cc3cc(F)ccc3s2)CC1CN +COc1ccc(C=C2N=C(CC(C)C)C(=O)N(O)C2=O)cc1 +CCC(CC)C(=O)C1OC(C(=O)O)=CC(N)C1NC(C)=O +COc1cccc(NC(=O)c2ccc(-c3ccccc3)cc2)c1 +CCOC(=O)C1C2CCC(CC1c1ccc3c(ccn3CC)c1)N2 +Cc1cc(C)c2oc(-c3cc(Br)c(O)c(Br)c3)cc(=O)c2c1 +O=S(=O)(c1ccccc1)c1cc(C(F)(F)F)c2oc3c(c2c1)CNCC3 +Cc1cc(Nc2nn(C(C)C)c(=O)c3cc(CO)ccc23)[nH]n1 +CCCN(CC1CC1)C(=O)c1sc(Nc2c(Cl)cc(Cl)cc2Cl)nc1C +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(C(=O)C2CCCO2)CC1 +CCN(CC)CCOc1ccc(C2Oc3cc(O)ccc3-c3sc4cc(O)ccc4c32)cc1 +COc1cc2ncnc(Nc3cc4ccccc4cn3)c2cc1OC +C=CCN(C(=O)OCc1ccccc1)C1CCN(CCC(C)(c2ccccc2)C2Nc3ccccc3S(=O)(=O)N2)CC1 +CC(C)Nc1nc2c(S(=O)(=O)c3cccc(Cl)c3)nnn2c2ccsc12 +CS(=O)(=O)Nc1ccc(OCC(O)CN(CCc2ccc(Cl)c(Cl)c2)Cc2ccccc2O)cc1 +Nc1nccc(Oc2ccc(NC(=O)C3(C(=O)Nc4cccc(F)c4)CC3)cc2F)c1Cl +O=C(C=Cc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cc1)NO +CC1=CC(C)=[N+]2C1=Cc1ccc(C=Cc3ccc(-c4ccc(I)cc4)s3)n1[B-]2(F)F +CC(C)(C)CCN1CCC(CNC(=O)Nc2cccc(Cl)c2)(c2ccccc2)CC1 +Fc1cccnc1ON=C1C=C(C#Cc2ccccn2)CCC1 +O=C(NCc1cccc(F)c1)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CC(NC(=O)c1cccc2c1N(Cc1ccc(-c3ccccc3)cc1)CC2)c1ccc(C(=O)O)cc1 +Nc1ccc(S(=O)(=O)c2cc(Br)nc(N3CCNCC3)c2)cc1 +O=C(COc1cccc2[nH]cc(S(=O)(=O)c3ccc(Cl)cc3Cl)c12)NS(=O)(=O)c1cc(Cl)c(Cl)s1 +O=C1c2ccccc2C(=O)N1CCCCCCCCN1CCN(Cc2ccccc2)CC1 +O=C(NCC1CCN(c2ccc3ccccc3c2)C(=O)C(CCN2CCCCC2)N1)C1=NOC(c2ccc(Cl)cc2)C1 +CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)cn1CCO2)c1ncns1 +CNCC(=O)N1CCN(c2cnc3ccn(S(=O)(=O)c4cccc5nonc45)c3c2)CC1 +CNC(=O)C(CC(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CCCO2)n1 +CN(C)CCCNC(=O)c1cc(NC(=O)c2cc(NC(=O)c3cc4ccccc4cn3)cn2C)cn1C +CC1(CC(O)(Cc2cc3ccccc3[nH]2)C(F)(F)F)CCCc2ccccc21 +CC1CCN(CCCC=C(c2ccccc2)c2ccccc2)CC1 +CC12CCCC(C=CC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)=C1N(Cc1ccc(Cl)cc1Cl)C(=O)C2 +COc1cc(Nc2cncc(Oc3ccc(NC(C)=O)c4ccccc34)n2)cc(OC)c1OC +COc1cc(OCCN2CCCC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +O=C(Nc1ncccn1)c1oc2cnccc2c1Nc1ccc(Cl)c(O)c1 +COc1ccc(CN(C)CCc2ccc(NC(=O)c3cccc4c(O)c5cccc(C)c5nc34)cc2)cc1OC +CC(=O)NC(C)Cc1ccc(C#Cc2ccc(-n3cccc3)cc2)cc1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(COc2ccc3c(c2)CCCC3)cc1F +CCCCCn1c(=O)n(CC(=O)NC2CCCCC2)c(=O)c2c(C)cccc21 +N#Cc1ccc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)cc1C(F)(F)F +Oc1ccc2c(c1)C13CCN(CC4CCC4)C(C2)C1Cc1c([nH]c2ccccc12)C3 +COCC(C1CC1)n1nc(C)nc(Nc2c(Cl)cc(OC(F)(F)F)cc2Cl)c1=O +Nc1ncc(-c2ccc(-c3ccccc3Oc3nccc(C(F)(F)F)n3)cc2F)cn1 +CC(C)N1CCN(c2cccc3nc(CN(C)C4CCCc5cccnc54)cn23)CC1 +Cc1[nH]c2ccccc2c1CCN(CCF)Cc1ccc(C=CC(=O)NO)cc1 +CCOC(=O)CSc1ccc(C(=O)Nc2ccc(OC)cc2)cn1 +OC(CNCC1CCCO1)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21 +COc1ccc2sc(S(=O)(=O)NC3CCN(Cc4cc(C(=N)N)ccc4N)C3=O)cc2n1 +CC(=O)Nc1nc(C)c(-c2csc(NCCc3n[nH]c(=O)o3)n2)s1 +CC1C=CC=C1C(=O)N1CCN(C(=O)NC2CCN(c3ccc(C(=O)N4CCCC4)cc3)CC2)CC1 +NC(=O)c1ccc(CNC(=O)NCC2CN(Cc3ccc(Cl)c(Cl)c3)CCO2)cc1 +COCCCOc1cc(C(=O)N(CC2CNCC2OCc2cccc(-c3ccccc3OC)c2)C(C)C)ccc1OC +Cc1cc(SC2=C(O)OC(CCc3ccccc3)(c3ccccc3)CC2=O)c(C(C)(C)C)cc1N +COc1ccccc1NCCCCCCNCCCCCCCCNCCCCCCNc1ccccc1OC +CC12CCC3C(CCC4=CC(=O)NCCC43C)C1=CC=C2c1cncc(F)c1 +COc1cc2c(N3CCN(C(S)=NCc4csc(C)n4)CC3)ncnc2cc1OCCCN1CCCCC1 +N=C(NCCCC(N)CNc1ccccc1CCN)N[N+](=O)[O-] +CCCS(=O)(=O)NC1CNCC1CN(C(=O)c1ccc(OC)c(OCCCOC)c1)C(C)C +CC(=NOC(CO)CO)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +CN1C2CCC1C1COC(=O)CCCCCCCCC(=O)Nc3ccc(cc3)C1C2 +CC(C)c1onc(CSc2nnnn2C)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +O=C(Nc1ccc(C2CCN(C(=O)C3CCOC3)CC2)cc1)N1Cc2ccncc2C1 +Cc1nc(-c2ccccc2)oc1CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +CC(C)n1cc(-c2cnc3[nH]cc(-c4cc(C(C)(O)c5ccccc5)nc(N)n4)c3c2)cn1 +CN(c1ccccc1)c1ccc2cc(-c3n[nH]c4ccccc34)[nH]c2c1 +Cc1cc(COc2ccc(C(=O)NCC3(C)NC(=O)NC3=O)cc2)c2ccccc2n1 +O=C(CN1CCC(c2ccccn2)CC1)Nc1c(Cl)cc(Cl)cc1Cl +CC(C)=CCc1cc(C(=O)Nc2cc3ccc(OCCCN(C)C(C)(C)C)c(C)c3oc2=O)ccc1O +COc1ccc(Cl)cc1N1CCN(CCn2cnc3sc4c(c3c2=O)CCN(C)C4)CC1 +O=S1(=O)N=C(Nc2ccccc2F)Nc2c(O)cc(Cl)cc21 +c1cc2c3cnc(Nc4ccc(N5CCNCC5)cn4)nc3n(C34CC5CC(CC(C5)C3)C4)c2cn1 +CC1C2Cc3ccc(C(N)=O)c([N+](=O)[O-])c3C1(C)CCN2CC1CC1 +COc1cc(C=C[N+](=O)[O-])c(C=Cc2ccccc2)c(OC)c1OC +N#Cc1ccc(NC(=O)COc2cccc(C(=O)Nc3nc4c(s3)CC(N3CCN(C5CC5)CC3)CC4)c2)cc1 +Fc1ccc(-n2ncc3c(-c4cncc5ccccc45)ccnc32)cc1 +CN1C2=NC3C=CC=CC3C2=C(NCCCO)c2ccccc21 +CCCCN(CC)c1nc(C)nc2c1ncn2-c1c(Cl)cc(OC)cc1OC +COc1ccc(F)cc1-c1cc(NC(=O)C2CCCNC2)ncn1 +Cc1nc2nc(C(=O)NC3CCN(C(C)C)CC3)cn2c(-c2ccc(Cl)cc2Cl)c1CN +CCC1CC(=O)NN=C1c1ccc2nc(-c3cccc(OCc4cccnc4)c3)oc2c1 +Cn1c(=O)c2c(nc(COc3ccc(Br)cc3)n2C)n(C)c1=O +O=S(=O)(NCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1cccc(O)c1 +CC(C)CC(CO)NC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +CCn1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(Cl)cc4)cc3=O)cc21 +CC(C)NC(=O)Nc1ccc2c(c1)C(=O)N(C(C)CO)CC(C)C(CN(C)S(=O)(=O)c1ccc(Cl)cc1)O2 +O=C(Nc1ccc(Cl)c(S(=O)(=O)C2CCNC2)c1O)Nc1cccc(F)c1Cl +COc1ccc(S(=O)(=O)N2CCC(NCC(O)COc3ccc(O)cc3)CC2)cc1 +CCOc1ccnc(-c2cnc(N)c(C(=O)Nc3ncccc3N3CCC(C)(N)CC3)n2)c1F 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+CN(C(=O)CS(=O)(=O)c1ccc2cc(Cl)ccc2c1)C1CCN(c2ccncc2)CC1 +CN(O)C(=O)CC(CCCCc1ccccc1)CP(=O)(O)O +O=C(Nc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccccc1)OCc1ccc(Cl)cc1 +CN(CC(=O)Nc1cccc(S(N)(=O)=O)c1)C(=N)N +COc1cc(O)c2c(c1)oc(=O)c1c3cc(O)c(O)cc3oc21 +O=C(O)CN1C(=O)C2(CC(=O)N(Cc3nnc(C4CC4)s3)C2=O)c2cc(Cl)ccc21 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3ccccc3)nc21 +O=C(CCCCCN1C(=O)c2ccc(I)cc2S1(=O)=O)NO +Cc1noc(C2CC3CSC(N)=NC3(c3ccc(F)cc3F)CO2)n1 +CCCCNC(=O)NS(=O)(=O)c1ccc(OCc2no[n+]([O-])c2-c2ccccc2)cc1 +COC(=O)c1ccc(-c2cc(=O)c3ccccc3o2)cc1 +O=C(NCc1ccco1)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 +OCc1cccc(C(O)CNCc2ccccc2OCc2ccccc2)c1 +CC(C)NC(=O)C1CCC(n2c(=NC(=O)c3ccc(F)cc3)[nH]c3ccc(CN4CCCCC4C(=O)O)cc32)CC1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(CCc1cccc(Oc3ccc(C)cc3)c1)CC2 +CCCCCCCCCCCC(c1ccc(Cl)cc1)c1c(O)c2ccccc2oc1=O +C=C(C)C1CCC(C)=CC1c1c(O)cc(CCCCC)cc1O +Fc1cnc(Nc2ccc(N3CCOCC3)cc2)cc1-c1ccn(CCN2CCOCC2)n1 +Cn1nc(C(N)=O)cc1Nc1nccc(-c2ccc(N3CCCC3)c(C#N)c2)n1 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+CN1CCN(c2ccc(NC(=O)c3c(NCCc4ccc(Cl)cc4)cc[nH]c3=O)cc2)CC1 +Cc1cc(C(=O)Nc2cn3nc(-c4cn(C)nc4-c4ccc(F)cc4)ccc3n2)ccn1 +CN(C)CCOc1cc(-c2cn[nH]c2)c(F)cc1NC(=O)C1Cc2ccccc2CN1C(=O)CN(C)C +CC(C)NC(=O)C(F)CNc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(F)C(C)(C)O +CC(C)(Cc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)NCCCCC2CCCCC2)co1)C(=O)O +Cn1c2c(c3cc(Cl)ccc31)CN(CCCOc1ccc(F)cc1)CC2 +CCCC(Sc1nc(N)c2cnn(-c3ccccc3)c2n1)C(N)=O +COC(=O)c1ccc(N2CCN(C)CC2)c(NC(=O)c2cc([N+](=O)[O-])c(F)c(C)c2Cl)c1 +O=C(NCCc1ccccn1)C(c1cn[nH]c1)N1CCN(c2ccc(Cl)c(Cl)c2)CC1 +Cc1cc(-c2cnn(CCC(=O)O)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CCOCc1cc2cnc(Nc3ccc(N4CCOCC4)cn3)nc2n(C2CCCC2)c1=O +CCOC(=O)C(Oc1ccc2c(c1)CN(C(=N)N)CC2)c1ccc(OC2CCNC2)cc1 +Cc1ncc(C)n2nc(-c3ccn4cc(C5CC5)nc4c3)nc12 +CCN1CCCC1CNC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +CC(c1ccccc1)N(C)c1ccc(C(Cc2cc[n+]([O-])cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cn1 +O=C(NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(C2CCCCC2Cn2cncn2)CC1)C1Cc2ccccc2CN1 +COc1cc(C(=O)NCCc2cccc(C(F)(F)F)c2)ccc1-c1cn[nH]c1 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+COc1cccc2c1ncc1c(=O)n(-c3cccc(Cl)c3)c(=O)n(C3CCN(S(=O)(=O)c4ccccc4)CC3)c12 +CNCCCN1c2ccccc2N(c2ccccc2F)S1(=O)=O +CC(C)CN(CC(O)C(Cc1cccnc1)NC(=O)OCc1cncs1)C(=O)c1ccc2ncsc2c1 +CCC(C(=O)NC(CC(=O)O)C(=O)CNCN1CCC(Cc2ccccc2)CC1)n1ccnc(NCc2nonc2C)c1=O +CC1CN(C(=O)c2nc(Nc3cc(C4CC4)[nH]n3)c3cc(Cl)ccc3n2)CC(C)N1 +CN(C)CCCCn1cnc2c(O)nc(Nc3ccccc3)nc21 +O=S(=O)(Nc1ncns1)c1ccc2c(-c3ccc(C(F)(F)F)cc3O)nccc2c1 +CS(=O)(=O)CCCOc1ccc(-c2cc(F)cc(C3COc4cc5c(cc4O3)OCC5CC(=O)O)c2)c(Cl)c1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(CO)(Cc5ccccc5F)C4)cc23)ccn1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(Oc2ccc(Cl)cc2Cl)CC1 +CC(NC(=O)C=Cc1ccccc1F)c1cccc(Oc2cccnc2)c1 +COc1cc(-c2ncoc2-c2ccc(OC)c3c2ncn3CCCO)cc(OC)c1OC +CC(N)c1ccc(-c2c(O)cc(Br)c3[nH]c(=O)c4sccc4c23)cc1 +Cc1ncc(CN2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccnc(F)c4)n3)CC2)s1 +CN1CCN(c2ccc(-c3nc(Cl)c4c(n3)N(CCCN3CCCC3)CC4)cc2)CC1 +COc1cc(Cn2c(N)nc3cc(-c4cnn(C)c4)cnc32)ccc1OCc1csc(C(F)(F)F)n1 +Cc1ncc2c(-c3ncc4c(n3)NC(=O)C4(C)C)nn(Cc3cccc(F)c3F)c2n1 +Cc1ccc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)nn1 +O=C(O)c1ccn(Cc2cc(Br)ccc2OCc2ccccc2)n1 +N=C(N)NC(=O)c1ccc(C2CCN(C(=O)c3ccccn3)CC2)c(C(F)(F)F)c1 +CCOC(=O)c1c[nH]c2ncnc(-c3cccc(NC(=O)C4(C)CO4)c3)c12 +O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1cc2ccccc2cn1 +CN1C(=O)C(=O)c2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)cc3)cc21 +COc1nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)nc(N2CCCC2C(N)=O)n1 +NC(=O)c1cc(N(CCBr)CCBr)c([N+](=O)[O-])cc1[N+](=O)[O-] +CC(Nc1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1)c1cccc2ccccc12 +CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2-c2nnccc2N)cc1 +O=C(O)C1CCC(NC(=O)C2(CS)CCc3ccccc3C2)CC1 +Cc1cc(C)nc(NS(=O)(=O)c2ccc(N=Cc3c(Cl)c4ccccc4oc3=O)cc2)n1 +Cc1nn(Cc2ccccc2-c2cc3ccc(Cl)cc3[nH]2)c(C)c1CC(=O)O +O=c1c(C2=NS(=O)(=O)c3cc(OCn4cnnn4)ccc3N2)c(O)c2cc(F)ccc2n1CCC1CC1 +CCc1ccc(C(=O)C(=O)N2C3CCCC2C2c4c(cc(OC)cc4OC)CCN2C3=O)cc1 +COc1cccc(C(=CC#N)c2ccc(OC)c(OC)c2)c1 +Cc1nc2cc3c(cc2n1-c1ccccc1)C1CNCC3C1 +O=C(NCc1ccncc1)c1cnc(Oc2ccc3c(c2)CCC(c2cccc(F)c2)O3)s1 +Fc1ccc(C2(c3ccc(F)cc3)CNC(c3cnccn3)=N2)cc1 +Cc1ccc(-c2nc3c(S(=O)(=O)c4cccc(Cl)c4)nnn3c3ccsc23)cc1 +CC(C)S(=O)(=O)c1cc(C#Cc2cc(Cl)ccc2OCC(=O)O)ccc1C(=O)N(C)C +O=C(O)C(CC1CC1)N1CC(CN2CCC(CCCc3ccccc3)CC2)C(c2ccccc2)C1 +FC(F)(F)c1cccc(-c2ncccc2CC(c2cccnc2)c2cccnc2)c1 +Nc1cccc(S(=O)(=O)NC(=O)c2c(-c3ccc[nH]c3=O)c3cc(Cl)ccc3n2Cc2ccnc(N)c2)c1 +CC(Cc1ccccc1)(Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)oc4ccccc34)cc2)cc1)C(=O)O +CCCCCN(C(=O)c1cccc([N+](=O)[O-])c1)C(CC)c1nc2ccccc2c(=O)n1-c1ccccc1OC +CC(C)(CNCCCc1ccccc1)CNCCOC(c1ccccc1)c1ccccc1 +CC(Nc1ccc(F)cc1)c1cc(C(=O)NCCN(C)C)cn2c(=O)cc(N3CCOCC3)nc12 +N=C(N)c1ccc(OCCCCCOc2ccc(C(=N)N)nc2)cn1 +O=C(Cc1ccccc1)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +Cc1onc(-c2ccccc2Cl)c1C(=O)N(C)c1cc(Br)c(C)c(Br)c1 +Cc1cc(=O)n2nc(-c3ccccc3)n(Cc3ccccc3Cl)c2n1 +CCOc1ccc(-n2c(C)c3c(C)nnc(Nc4ccc5c(c4)CCC5)c3c2C)cc1 +CC1CCCN1CCc1ccc(-c2ccc(S(=O)(=O)Cc3ccccc3)cc2)cc1 +CN1C(c2nc(CC(=O)O)cs2)C(c2cccc(Cl)c2F)C2(C(=O)Nc3cc(Cl)ccc32)C12CCCCC2 +O=C(O)c1[nH]c2cc(Cl)ccc2c1C(NCC1CCCCC1)c1nnnn1-c1ccc(Cl)cc1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3-c3ccccc3)ccc21 +CCOc1ccc(C(C)Nc2nc(N3CCN(C(C)=O)CC3)nc3c2CN(C(C)C)C3=O)cc1F +Nc1cccc(CN2C(=O)N(Cc3ccc4ccccc4c3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)c1 +Cc1nnn(-c2ccc(F)cc2)c1COc1cc(C(=O)NC2(C)COC2)n(C)n1 +O=C(c1ccc([N+](=O)[O-])cc1)C1CCN(CCc2ccccc2)CC1 +NS(=O)(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)cc1 +Cc1cccc(N2CCN(CC(O)CNC(=O)c3nc(C)n(-c4ccccc4)c3C)CC2)c1C +O=C(C1=C(O)C(=O)N(Cc2cccnc2)C1c1ccccn1)c1ccc(F)cc1 +O=C(Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3Cl)nc12)N1CCC(O)CC1 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)OCCO3)cc1 +CC(=O)c1ccc2c(c1)N(CCCN1CCN(CCO)CC1)c1ccccc1S2 +COC(=O)c1ccc(Oc2ccc3c(c2)COB3O)nc1 +O=C1CC(c2c(Cl)ccc(N3CCOCC3)c2Cl)CC(O)=C1Sc1ccccc1Cl +Cc1cc(-c2nc(C3CCCCN3C(=O)COc3ccccc3)no2)n(C)n1 +O=C(NCc1ccc(C(F)(F)F)nc1)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +NC(=O)c1c(-c2ccc(NC(=O)Nc3cccc(C(F)(F)F)c3)cc2)[nH]c2ccccc12 +O=C(OCC1CCCC(c2cc(F)cc(F)c2)N1S(=O)(=O)c1ccc(Cl)cc1)N1CCN(C2CCCCC2)CC1 +C=CCN(C)CC=CCOc1ccc2c(-c3ccc(Br)cc3)noc2c1 +COc1ccc(C2c3nc(NC(C)C)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)c(CCO)c1 +Cc1cc(C#N)cnc1C(=O)Nc1ccc(F)c(C2(C)COC(C)(C(F)(F)F)C(N)=N2)c1 +CC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3cnn(-c4ccccc4)c3n2)cc1 +COc1ccc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(Cl)cc1NC(=S)C2 +COc1cc(CC(=O)NCCCc2ccc(C)c(C)c2)ccc1O +CCNC(=O)Nc1nc2cc(-c3ccc(C)nc3)c(OCC3CCOC3)nc2s1 +N#CC(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1NC2CCC1C2 +C#CC1(O)CCC2C3CCC4=Cc5oncc5CC4(C)C3CCC21C +OCC(O)CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +CCN(C)C(=O)Cn1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +CCOc1cc(NC(=O)CCCCCNC(=O)C(N)Cc2ccccc2)cc2c1OCC([N+](=O)[O-])=C2 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(c4ccccn4)CC3)c(C(F)F)c21 +COc1ccc(Cn2nncc2-c2cc(OC)c(OC)c(OC)c2)cc1N +O=C(Cc1cn(Cc2ccc(F)cc2)c2ccc(Cl)cc12)Nc1ccncc1 +CCC1OC(c2ccc(Cl)c(Cc3cnc(-c4ccoc4)nc3)c2)C(O)C(O)C1O +Oc1ccc(-c2ccc3c(-c4ccccc4)c(O)ccc3c2)cc1 +O=C(O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)NCCCCc2ccc(F)cc2)co1 +CN1CC(COc2ccc(C(=O)N(C)c3cccc(CC(=O)O)c3)cc2)Oc2ccccc21 +CC(C)c1ccc(CC(C)(C)NCC(O)c2cc(O)cc3c2OCC(=O)N3)cc1 +Cc1c(C(=O)NC2CCOCC2)cc(-c2cc(C(C)(C)C)c3c(c2)C2(CCO3)CC2)n1CC1CCCCC1 +Cc1ccc(N2CCc3ncnc(NC(C)c4ccc(Cl)cc4)c3C2)nc1 +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)c2cccc(C(F)(F)F)c2)CCC3(O)C1C5 +CCc1nc(Cn2nnc3c(N)nc(C4CC4)nc32)cs1 +O=C(NCC1CCN(c2nsc(Cc3ccc(F)cc3)n2)CC1)Nc1ccc(Cl)c(Cl)c1 +CC(NC(=O)C(=O)Nc1cccnc1N(C)C)C(=O)NC(CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F +COC(=O)NC(C)CNc1nccc(-c2nc(C3CC3)[nH]c2-c2cc(Cl)cc(NS(C)(=O)=O)c2Cl)n1 +Cc1ccc(CNC(=O)C2SC(n3cnc4c(NCc5cccc(I)c5)ncnc43)C(O)C2O)cc1 +CCCCc1nc(-n2cccc2)c(C(=O)O)n1Cc1ccc(NC(=O)C(Cc2ccccc2)n2cccc2C(=O)O)cc1 +CC(C)(C)c1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 +O=C(NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5)c1ccncn1 +CCc1cn(C2CC(O)C(CNC(=O)C3c4ccccc4Cc4ccccc43)O2)c(=O)[nH]c1=O +COc1ccccc1OCCNCC1COCC(c2ccccc2)(c2ccccc2)O1 +Cn1c(CN2CCN(c3nc(Cl)ccc3C(F)(F)F)CC2)nc2cc(C#N)ccc21 +NC(=O)C(c1ccccc1)C1CCCCN1Cc1ccccc1 +COc1ccccc1Cn1c(N2CCCC(N)C2)nc2c3cc(C(=O)O)ccc3n(C)c(=O)c21 +Cc1c(C)c2ccc(OCc3ccc(CN(C)Cc4ccc(C#N)cc4)cc3)cc2oc1=O +CCOC(=O)c1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccn3)c2c1 +Cc1c(-c2cc(Nc3cc4n(n3)CCN(C)C4)c(=O)[nH]n2)cccc1N1CCn2c(cc3c2CCCC3)C1=O +O=C1CN(c2ccccc2)C(=O)N1S(=O)(=O)c1ccc(F)cc1 +CC(C)(O)C#Cc1ccc2c(c1)-c1nc(C(N)=O)c(C(F)(F)F)n1C1CC2C1 +CC(C)(C)C1(O)CCN(CC2c3ccccc3CCc3cc(Cl)ccc32)CC1 +CNCCN(C)c1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(C#N)cc12 +CCOC(C)CNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CC(C)Oc1ccc2c(c1)C(c1ccc3c(c1)OCO3)=C(C(=O)O)C(c1ccc3c(c1)OCO3)O2 +COc1ccc2c(c1)CCc1c-2c2c(c3c4ccccc4n(CCCO)c13)CNC2=O +CN1C(CC(=O)c2ccccc2)CCCC1CC(OS(=O)(=O)Cc1ccccc1)c1ccccc1 +COc1cc(C=C[N+](=O)[O-])c(C=Cc2ccc(Cl)cc2)c(OC)c1OC +Cc1cnc(NC(C)C)nc1-c1ccc2c(c1)CCC(C)N2C(=O)c1ccc(O)cc1O +CC(C)Cc1ccc(N2CCc3cc(O)ccc3C2(C)c2ccc(C=CC(=O)O)cc2)c(F)c1 +Cc1cccc(OC(CC2CNC2)c2ccc(Cl)c(F)c2)c1 +CC(NC(=O)C(C)(Cc1c[nH]c2ccccc12)NC(=O)OCc1cccc(N)c1)c1ccccc1 +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCCN4CCSCC4)cc3)oc2c1 +CCCCC1=NC2(CCCC2)C(=O)N1Cc1ccc(-c2ccccc2-c2noc(O)n2)cc1 +Cc1oc(C2CC2)nc1CC(=O)Nc1cncc(C(=O)c2cn(C(C)C)c3ccncc23)c1 +Cc1ccc(C(=O)N2CC(F)(c3ccc(C#N)cc3)C2)cc1-c1[nH]nc(Cl)c1C +O=C(NC1CC1)c1cc2c(s1)-c1ccccc1N(C(=O)c1ccc(NC(=O)c3cccnc3N3CCOCC3)cc1)CC2 +COc1ccccc1C1C(C(=O)C2(CO)CCCCC2)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +Cc1c(C(=O)NC(C)(C)c2cn3ccsc3n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(CCCCCCNC(=O)c1ccc(C(CO)(c2ccccc2)c2ccccc2)cc1)NO +CCOc1ccc(CC(NC(=O)c2ccc(C)cc2)C(=O)NC(Cc2cscn2)C(=O)NCc2ccc(CN)cc2)cc1 +CN1CCC2(CCN(c3cc(NC(=O)N4CCCc5ccc(C=O)nc54)ncc3C#N)CC2)C1 +CN(CCN1CCCCC1)C(=O)N1CCN(c2cccc(Cl)c2)CC1 +CCOCCn1cc(C(=O)c2ccc(Cn3c(C)nc4cnccc43)cc2)c2c(C(=O)OC)cccc21 +CC1(C(F)F)CC(NC(=O)Nc2ccc3c(c2)NC(=O)CC3)c2ccccc2O1 +COc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2n1 +O=C(C(O)c1ccccc1)N1CCC2CC21C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +CN1C2COCC1CC(NC(=O)c1cn(CC(F)F)c3ccc(F)cc13)C2 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC1(C)C +CC(C)C(CC(N)=O)NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1 +CC(C)(O)Cn1cc(-c2ccc3c(c2)OCCc2sc(-c4ncnn4CC(F)(F)F)nc2-3)cn1 +N#Cc1ncccc1CSc1nc(O)c(C#N)c2c1CCCC2 +Cc1ccc(-c2noc(C3(N(C)C)CC3)n2)cc1NC(=O)c1cnc2ccccn12 +Cc1ccc(S(=O)(=O)NC(=O)c2ccc(Cl)cc2Cl)cc1 +CCCC(=O)C1(c2ccccc2)CCN(C(=O)c2ccc3[nH]ccc3c2)CC1 +CC(C)(C)c1ccc2c(c1Cl)CCN2C(=O)Nc1cccnc1 +Cc1nc(C(F)(F)F)ccc1Cn1c(=O)c(-c2ccncc2)c(-c2ccc(Cl)cc2)c2nn(C)c(=O)n21 +CC(C)c1nc2c(c(Nc3ccc(C(F)(F)F)c(Cl)n3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +Cc1ncc(-c2ccc(Nc3cc4cc(-c5cnn(CC(C)(C)O)c5)ccc4cn3)cc2)n1C +O=c1cc(N2CCOCC2)c2ccc(-c3cccs3)cc2o1 +Cc1cc(NC(=O)N2CC=C(c3ncc(-c4nc(CO)no4)cc3Cl)CC2)ccc1C(F)(F)F +CC(=O)Nc1cc(-c2ccccc2)c(-c2nnc(S)n2N)s1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCNC(CO)CO)CCCC1)c1cc2ccccc2s1 +C=C(Br)C(=O)Nc1cccc(C=C2SC(=O)N(Cc3ccccc3)C2=O)c1 +CC(Oc1ccc2[nH]nc(-c3nc4ccccc4s3)c2c1)c1c(Cl)cncc1Cl +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2N(C)C)N2C1=NC1CCCC12 +O=C(Nc1ccc2cn[nH]c2c1)c1cnc(N2CCOCC2)c(Cl)c1 +N#Cc1cc2ccc(N3CCOCC3)cc2n2c1nc1ccccc12 +O=C1C(=Cc2ccc(F)cc2)CNCC1=Cc1ccc(F)cc1 +CC(C)c1cc(Nc2ccnc(NCc3cc(-c4ccccc4)no3)n2)[nH]n1 +CC(O)(COc1ccccc1C(F)(F)F)C(=O)N1CCc2c(C#N)cccc21 +Cn1nc(S(N)(=O)=O)sc1=NCc1cc(=O)oc2cc(Cl)ccc12 +CC(C)(CNC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1)N1CCOCC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N4CCCC4(C)C)ncc3F)C2)cc1 +CCCCC(NC(=O)OC(C(C)C)C(C)C)C(=O)C(=O)NC(C)c1ccccc1 +CC(C(=O)Nc1ccc(-c2ncc[nH]2)cc1)n1ccc(-c2cc(Cl)ccc2C#N)cc1=O +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(CC3CCN(C(=O)OC(C)(C)C)CC3)C2=O)cc1 +CC(=O)N1Cc2ccc(NC(=O)c3ccccc3)cc2CCc2ccccc21 +N#Cc1c(-c2cc(C(F)(F)F)ccc2Cl)cc(-c2cc(Cl)ccc2O)[nH]c1=O +N=C(N)c1ccc(OCc2ccc([N+](=O)[O-])cc2)c(I)c1 +Cc1nnc2c3ccccc3c(-c3ccc(N4CCOCC4)c(NS(=O)(=O)c4ccccc4Cl)c3)nn12 +O=C(c1ccc(F)cc1)C1CCN(C2CN(C(=O)c3ccccc3)CCC2O)CC1 +Cc1ccnc(NC(=O)c2ccc3cc4n(c3n2)CCCNC4=O)c1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(NC3CCOCC3)cc(-c3ccccc3)n2)CC1 +O=S(=O)(NCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2ccccc2c1 +NC(=O)c1sc(-c2cnn3ccccc23)cc1OCc1ccccc1C(F)(F)F +CN(C1CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)C1)S(C)(=O)=O +CC(NC1=NC(=O)C(C)(C(C)C)O1)c1ccccc1 +CC(C)COC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +COc1cccc(C2CCOP(=O)(COc3cc(C)c(C)c4c3-c3ncsc3C4)O2)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1nc(-c2ccc(F)cc2)no1 +CN(C)C(=O)c1sc2ncnc(N3C4CCC3CC(N(C)C3CCC3)C4)c2c1-c1ccccc1 +CCc1cc(OC)c(C(=O)Nc2cccc3c2CCN(C)C3)cc1Cl +CC(C)CC(NC(=O)c1ccc(NCc2c[nH]cn2)cc1-c1ccccc1)C(=O)O +CCn1c(CN2CCN(Cc3ccccc3)CC2)nc2cc(NC(=O)c3cccs3)ccc21 +Cc1ccc2c(c1CCC(=O)C(C)(C)O)C(=O)C(=O)C(C(C)C)=C2 +O=S(=O)(Nc1cccc(OCCNc2ccncc2)c1)c1ccc(F)cc1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1ccccc1OCC(F)(F)F +COc1cc(C(=O)c2cn(Cc3ccccc3)c(-c3ccc(C)cc3)n2)cc(OC)c1OC +C=Cc1cc(-c2ccc(O)cc2)nc2ccc(O)cc12 +CNC(=O)c1cn2ncnc(Nc3cc(NC(=O)c4cc(F)cc(N5CCOCC5)c4)ccc3C)c2c1C +COc1ccc2c(ccn2CCn2cc(NC(=O)c3ncoc3-c3cccc(C)c3)cn2)c1 +Cc1nc2ccccc2n1Cc1ccc(C(=O)NC2CN(C(=O)OC(C)(C)C)CC2C(=O)NO)cc1 +O=C(OC1CCNC1)C(O)(c1ccccc1)c1ccccc1 +NC(=O)C1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1 +COc1ccc2[nH]cc(Cc3[nH]c4ccccc4c3C=O)c2c1 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+O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(-c3cnccn3)cnc2C1 +COC(=O)C1C(c2ccc(I)cc2)CC2CCC1N2CCF +CC(Oc1cc(-c2cnoc2)cnc1N)c1c(Cl)ccc(F)c1Cl +CCCCNC(=O)C(C)CC(O)C1CSCCCCSCC(NC(C)=O)C(=O)NC(C)C(=O)N1 +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NC(CO)C(O)c1ccccc1 +O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +O=c1ccc(Cc2cc(Oc3cccc(Cl)c3)c3occc3c2)n[nH]1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2Cc3[nH]ncc3C1CC(c1ccccc1)C2 +CC(=O)NC(C)c1ccc(OC2CCN(c3nccc(OCC4CC4)c3F)C2)cc1 +O=c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)nn1-c1ccc(F)c(Cl)c1 +CCOC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +CC(C)N(C)C1CCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)CC1CS(=O)(=O)c1ccccc1 +Cc1nc(-c2ccccn2)nc(N2CCC(Cc3ccccc3)C2)c1Cl +OC12C3C4CC5C6C4C1C6C(C53)N2Cc1ccccc1F +NC(=O)c1cccc(-c2c(-c3ccccc3)oc(=O)c3c2nn2c(-c4ccccc4)ccnc32)c1 +Cn1cc(-c2cnc3ccc4ccc(NS(=O)(=O)N5CCOCC5)cc4c(=O)c3c2)cn1 +Cc1ccccc1C(=CCCN1CCCC(C(=O)O)C1)c1ccccc1 +CCc1cn2c3c(cc(C(=O)NC(Cc4ccccc4)C(O)CNCc4cccc(OC)c4)cc13)N(C)S(=O)(=O)CC2 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+CC(=O)NC1C(NC(=N)NC(=O)Cn2cc(-c3ccccc3N)nn2)C=C(C(=O)O)OC1C(O)C(O)CO +CC(C)(C)SCC(=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O +Cc1cc(Nc2nc(Cl)cn(C(COC(=O)Nc3ccccc3)C3CC3)c2=O)c(C)nc1OC(F)F +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C(C)CNCc1cccc2[nH]ncc12 +O=C1CCC2c3c(-c4noc(C5CC5)n4)ncn3-c3ccccc3N12 +COc1cc(OC)cc(N(CC(O)CN2CCOCC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C1CCc2cc(C(c3ccco3)n3ccnc3)cc3c2N1CC3 +N#Cc1ccc(-c2ccc(OCCCN3CCC(N)C3)cc2)cc1 +CC(C)(Cc1ccc2ccccc2c1)NCC(O)COc1ccc(CCC(=O)O)cc1C#N +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)cc1OP(=O)(O)OC +O=C(CCCCC(=O)N1CC=CCCOc2cccc(c2)-c2ccnc(n2)Nc2cccc(c2)C1)NO +CCN(CCn1cc(-c2ccc(F)c(C)c2)nc1C1CCN(c2ncnc(N)c2C#N)CC1)C(C)C +CC(=O)NCC1CN(c2ccc3c(c2)CCCc2c(NCCN)n[nH]c2-3)C(=O)O1 +Nc1ncnc2c1ncn2C1OC(CNC(=O)CCCCCCC(=O)Nc2cccc3c2CNC3=O)C(O)C1O +CN(C)CCC=C1c2ccccc2COc2ccc(CC(=O)O)cc21 +COCCOCc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +CCc1cc(C(C)=O)c(O)cc1OCCCOc1cccc(Oc2ccccc2C(=O)O)c1 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+O=C(OCC(C1CCCCC1)n1c(-c2ccccc2)nc2ccccc21)C1CCN(c2nc3ccccc3n2Cc2ccccc2)CC1 +CC1(C)OC2=C(C(=O)C(=O)c3ccccc32)C1OC1CCCCC1 +CNC(=O)c1cc(Oc2ccc3nc(NC(=O)c4cc(C(F)(F)F)cc(C(F)(F)F)c4)sc3c2)ccn1 +COc1ccccc1C(C)NC(=O)c1ccc(Sc2ccc(N)cc2)c(Nc2ncnc3nc(C(C)C)ccc23)c1 +CCCCc1cc2c(=O)c(CC)c(C)[nH]c2cc1OCCOc1ccccc1 +Cc1nc(-c2nc(-c3ccc4cc(CCN5CCCC5C)ccc4n3)cs2)cs1 +O=C1C(=Cc2ccccc2)CC2(O)C3Cc4ccc(O)c5c4C2(CCN3CCCc2ccccc2)C1O5 +CN(C)c1ccc(CNC(COCc2ccccc2)C(=O)N2CCC3(CC2)CN(S(C)(=O)=O)c2ccccc23)cc1 +COc1ccc(-c2ccc(C#Cc3cccc(C#Cc4ccc(-c5ccc(OC)cc5)cc4)[n+]3C)cc2)cc1 +O=C(O)CN1CN(Cc2ccc(C(F)(F)F)cc2)S(=O)(=O)c2cc(Br)ccc21 +CCN(CC)CCn1ccc2cc(-c3ccc(Oc4ccc(F)cc4)cc3)ccc21 +O=C(c1ccc(-c2ccc(O)c(Cl)c2)cc1)c1ccc(F)c(O)c1 +Cc1cccc2c(NCCCN(C)C)c3c([N+](=O)[O-])ccc(C)c3nc12 +CCc1ccc(S(=O)(=O)c2nnn3c2nc(NCCCOC)c2sccc23)cc1 +O=C1CCc2cc(Nc3cc(C(F)(F)F)ccn3)ccc2N1 +COc1ccc(S(=O)(=O)N2c3ccccc3CCC2CCS(=O)(=O)N2CCC(NCC3CCOCC3)CC2)c(OC)c1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(CO)c1ccc(F)c(F)c1 +Cc1cc(C)n(-c2nc(Nc3ccccn3)cc(N3CCc4ccccc4C3)n2)n1 +O=C(CCC1CCCC1)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)CC1CCCCC1 +NC(=O)c1cccc(-c2ccc3c(C=O)c(O)ccc3c2)c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)N5CCC(F)(F)CC5)s4)nc23)N1 +NC(=O)C(Cc1ccccc1)NC(=O)C(CS)NC(=O)c1ccc2c(c1)OCO2 +Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C(F)(F)F)ccc3o2)cc1 +COc1cc2cc(-c3ccccc3)n(Cc3cccc(C(=O)O)n3)c2cc1C +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(CC(=O)N(C)C4CC(O)C4)CC3)cc12 +Cc1ccc(C(=O)NC2(C)COC2)cc1-c1ccc2cc(NC(=O)C3CC3F)ncc2c1 +CC12CCC3c4ccc(C(=O)NC5CCCC5C(=O)O)cc4CCC3C1CC=C2c1cncc(F)c1 +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cn(C)nc3C)nc12 +Cc1nc(COc2ccc(C(=O)Nc3cc(NC(=O)c4cc(F)cc(N5CCOCC5)c4)ccc3C)cc2)cs1 +CC(C)c1nc(-c2cccnc2)c(-c2ccc(F)cc2)n1C=CC(O)CC(O)CC(=O)O +COc1ccc(Cc2nnc(C3(C)CCc4c(C)c(O)c(C)c(C)c4O3)o2)cc1OC +O=[N+]([O-])c1cc(O)c2c(c1)S(=O)(=O)N=C(Nc1ccccc1Br)N2 +NC1=NC(=O)C(=C2CCNC(=O)c3[nH]c4c(Br)csc4c32)N1 +Cn1c(-c2ccccn2)c(C2CCCC2)c2ccc(C(=O)NC3(C(=O)Nc4ccc(C=CC(=O)O)cc4)CCC3)cc21 +COc1cccc2c1nc(N)n1nc(CN3CCN(c4ccc(F)cn4)CC3C)nc21 +Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1c(F)cc(O)cc1F +COc1cc(C=CC(=O)OCCCCO[N+](=O)[O-])ccc1OCCCCO[N+](=O)[O-] +N=C1NC(c2ccccc2)(c2cccc(OCc3ccccc3)c2)C(=O)N1C1CCCCC1 +COC(=O)c1cc2occc2n1CC(=O)c1cccc(Br)c1 +COc1ccccc1CNc1ncc(C#Cc2ccc(CC(C)NC(C)=O)cc2)cn1 +N=C(N)c1ccc(C2C3C(=O)N(Cc4cccc(F)c4)C(=O)C3C3CCCN32)cc1 +CC(C)S(=O)(=O)NCC1CCC(NCCN2CCCc3cc(Cl)ccc32)CC1 +CCC1C(C)=NN=C(c2ccc(OC)c(OC)c2)c2cc(OC)c(OC)cc21 +CC1CN(c2ccc(Nc3ncc4c5ccccc5n(C5CCCC5)c4n3)nn2)CCN1 +CC(C)NC(=O)c1nc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cc(N)c1C#N +CC1(c2cccc3ccccc23)C(=O)N(CCCn2ccnc2)C(=O)N1Cc1ccc(CN)cc1 +N#Cc1cn(-c2ccc(C(=O)O)cc2)cc1-c1cccc(CO)c1 +CN(C1CCC1)C(C)(C)c1nc2c(C(N)=O)cccc2[nH]1 +N#Cc1c(-c2ccc(NC(=O)CCCC(=O)O)cc2)cc(-c2ccccc2O)nc1N +CCNC(=O)c1cc(C(N)=O)nn1-c1cccc(-c2ccccc2OC(F)(F)F)c1 +CNc1nccc(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)n1 +Cc1ncc(C)n2nc(CCc3nc(N4CCC(C(F)F)C4)nn3C)nc12 +CCCCCNC(=O)C(=O)C(Cc1ccccc1)NC(=O)C1Cc2cc3c(cc2S(=O)(=O)N1CC)OCCO3 +COc1ccnc(-c2ccnc(Nc3ccc4c(c3)CN(CCN3CCN(C)C3=O)C4)n2)c1 +COc1ccc(C2c3cc(OC)c(OC)cc3C(=O)C(C)C2C)cc1OC +Cc1cc(OCCN2CCN(c3ccccc3)CC2)nn1-c1ccc(Cl)c(Cl)c1 +CCOC(=O)c1cncc(N2CCC(C(N)Cc3cc(F)ccc3F)CC2)c1 +CCn1c(NC2CCCC2)nc2c(C#Cc3cccnc3)csc2c1=O +CC1(C)CC=C(c2cc(C(C)(C)N3CCCCC3)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +CCN(CC)CCn1c(CC(C)(C)C)nc2cc(C=CC(=O)NO)ccc21 +O=C(Nc1nc(-c2ccc(F)cc2)cs1)C(Cc1cnc[nH]1)NC(=O)C1OC1C(=O)O +CCN(CC)Cc1c(C)nc2n(-c3c(C)cc(C)cc3Cl)c3ncccc3n12 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)Cc3ccccc3)cc2F)CC1 +Cc1cccc(F)c1S(=O)(=O)NC1(C(=O)NC2C3CC4CC2CC(C(N)=O)(C4)C3)CC1 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCN1CCCCC1 +CC1(O)CCCN(S(=O)(=O)c2ccc(OCc3cccc(Cl)c3)cc2)C1C(=O)NO +Cn1cncc1C(N)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc3ccccc13)cc(=O)n2C +Oc1cc(NCCCNCc2cc(Cl)cc(Cl)c2Cl)nc2ccccc12 +COc1cccc(-c2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)c1 +O=c1cc(-c2ccc(Cl)cc2)oc2cc(OCCN3CCN(c4ccccc4)CC3)ccc12 +NC(=S)NN=C(c1cc(Br)cc(C(=O)c2ccccc2F)c1)c1ccccc1F +COc1cc(Nc2nc(NC3CCCCC3N)n3nc(C)nc3c2C(N)=O)cc(OC)c1 +Nc1nc(NCCc2cc(Br)cs2)nc2c1ncn2C1OC(CO)C(O)C1O +Cc1ccc(NS(=O)(=O)c2cccc3ccccc23)c(O)c1CC(=O)NCc1ccc(C(=N)N)cc1 +COc1cc(Cc2cnc(N)nc2N)cc(C#Cc2ccc(C(=O)O)cc2)c1OC +CCN(Cc1c(Cl)cncc1Cl)C(=O)CN1CCN(c2ccnc(NCCc3ccc(Cl)cc3)n2)CC1 +O=C(NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1)c1ccccc1 +CCC1CN(C(=O)C2(C#N)CC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cn(C)nc3C)cc12 +CC(=O)NCC1CN(c2ccc(-c3ccc(CNCc4ccco4)cc3)c(F)c2)C(=O)O1 +CCCCCCCCCCCCCC=CCC(O)C(O)C(N)(CO)C(=O)O +CC(=O)c1cc(F)c(Br)cc1NCC(=O)Nc1ccccc1C(=O)O +Cc1cc(N(C)CCO)nc2ccc(NC(=O)C=Cc3ccc(OC(F)(F)F)cc3)cc12 +Cc1c2c(=O)n(C)[nH]c2cc(=O)n1Cc1ccccn1 +CC(=CCC12OC(C)(C)C3CC(C=C4C(=O)c5c(O)cccc5OC431)C2=O)COC(=O)c1cccnc1 +CN(CCOc1cccc2ncnc(Nc3ccc(OCc4ccccn4)c(Cl)c3)c12)C(=O)CO +CS(=O)(=O)c1cccc(-c2cc(N3CCC(c4cc(F)c(F)cc4F)C(N)C3)ncn2)c1 +COc1ccc(N(C)c2nc(C)nc3c(Cc4ccccc4)cn(C)c23)cc1 +CCOC(=N)c1ccc(-c2ccc3cc(CCN4CCCC4C)ccc3n2)s1 +Fc1ccc(OC(c2ccc(F)cc2)C2CCNCC2)cc1 +Fc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cn1 +O=C(O)CCCN1CC(C(=O)O)Oc2c(NC(=O)c3ccc(OCCCCCc4ccccc4)cc3)cccc21 +CC(=NOCc1ccc(-c2ccccc2F)c(C(F)(F)F)c1)c1ccc(CNCCC(=O)O)cc1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1nc(-c2ccccc2)oc1Cl +O=C(C=Cc1cccn1Cc1cc(F)ccc1F)CC(=O)C(=O)O +CN1C(=O)CCC1(C)C(=O)NCc1ccc(Cl)cc1Cl +COc1ccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cn2)c(F)c1 +CC(CO)NC(=O)c1cnn2ccc(N3CCCC3c3cncc(F)c3)nc12 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(Cc2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCC(c1cccc(NS(=O)(=O)c2ccc(C#N)cc2)c1)c1c(O)c2c(oc1=O)CCCCCC2 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)CCN1CCCCC1 +O=C(O)c1nc2c(O)nc3cc([N+](=O)[O-])c(-n4cccc4)cc3n2n1 +CC(=O)Nn1c(Cc2csc(NC(=O)CCl)n2)nnc1SCC(=O)NNC(=O)c1ccccc1 +CC1(c2cc(CNCC(F)(F)F)c(F)cc2F)CCSC(N)=N1 +Cc1cccc(NC(=O)NC(CCC(=O)N2CCCC2)C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CSc1sc(C(=N)N)cc1S(=O)(=O)c1cc(Br)c2ncn(-c3ccccc3)c2c1 +CCN(C)c1nc2ccc(C(=O)N(CC(C)C)CC(O)C(Cc3ccccc3)NC(=O)OCc3ccncc3)cc2o1 +COCCn1cc(C2CCN(Cc3ccc(OC)c(C(=O)O)c3)CC2)c2ccc(F)cc21 +COc1ccc(C(=CC=CC(=O)NC(C)CCCc2cccnc2)c2ccccc2)cc1 +Cn1c(=O)n(C2CCOCC2)c2c3nc(-c4cc[nH]n4)ccc3ncc21 +CN(C)c1nn2c(-c3ccccc3)nnc2c2ccccc12 +CN1CCc2cc3c(c4c2C1Cc1ccccc1-4)OCO3 +COc1cccc2c1CCC1CN(CCCn3c(=O)[nH]c4c(sc5ccccc54)c3=O)CC21 +[N-]=[N+]=Nc1cccc(CCN2CCN(c3cccc(C(F)(F)F)c3)CC2)c1 +O=S(=O)(Nc1ccc2nccc(N3CCNCC3)c2c1)c1ccc(I)cc1 +CC(C)c1ccc(S(=O)(=O)NC(=O)C(c2ccc3c(c2)OCO3)c2c[nH]c3cc(C(=O)O)ccc23)cc1 +O=c1[nH]c(CCc2ccccc2)cc(Oc2ccccc2)c1I +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(Cl)cc1 +CC(C(c1ccc2cc(OCc3cccc(C(N)=O)c3)ccc2c1)n1ccnc1)N(C)C +O=C(COc1ccncc1)N1CCCCC1c1nnc(-c2cccc(C(F)(F)F)c2)[nH]1 +CN(C)c1ccc(Nc2ncc(Br)c(Nc3ccccc3)n2)cc1 +CC(c1ccc(-c2ccc(F)cc2)cc1)N1CCC(CCCO)(c2ccccc2)OC1=O +CC1OC(n2cc(-c3ccccc3)c3c(NCC(S)=NC4CC4)ncnc32)C(O)C1O +COc1ccn2c(c1)nc1c2c(=O)n(CCC(C)(C)C)c(=O)n1Cc1ccccc1 +CN1CCN(CCNc2cc(-n3ccnc3Nc3cc(Nc4ccc(OC(F)(F)F)cc4)ncn3)cc(C(F)(F)F)c2)CC1 +C=CCOC(=O)C1(C)CCC2(C)CCC3(C)C4=CC=C5C(=CC(=O)C(O)=C5C)C4(C)CCC3(C)C2C1 +Cc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc(Cl)cc2)ccc1OCCN1C(=O)CN(C)C1=O +CN(C)Cc1ccn2c(-c3ccnc(NCc4c(F)cccc4F)n3)c(-c3ccc(F)cc3)nc2c1 +Cc1cc(N2CCN(CCc3ccc4c(c3)NC(=O)CO4)CC2)c2ccc(C)nc2c1 +CC(C)(C)NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1 +O=c1nc(OCC2CCCO2)cc2n1CCc1cc(OCc3cccc(-c4ccoc4)n3)ccc1-2 +O=C(C=Cc1ccc(Cl)cc1)NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCCN2CCC=N2)N1 +Cn1cc(C(=O)Nc2ccc(-c3ccccc3)c(C(F)(F)F)c2)c(=O)c2ccncc21 +N=C(N)NCCCC(NC(=O)CCN1c2ccccc2Sc2ccccc21)C(=O)NC(Cc1ccccc1)C(N)=O +CCOC(=O)N1CCC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +CC(N)=NC(=NS(=O)(=O)c1ccc(F)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +O=C(O)c1c(Cc2cc3c(cc2Cl)OCO3)c(-c2ccccc2)nn1CC1CCC(C(=O)O)CC1 +Brc1cccc(Nc2ncnc3cnc(NCCc4ccccn4)cc23)c1 +CCCn1c2ccc(C(C)=NOC)cc2c2c3c(c4c(c21)CCc1nn(C)cc1-4)C(=O)NC3 +O=C(NCC1CC1)N(Cc1ccccc1)Cc1cccc(C#Cc2ccccc2)c1 +CCC(C)C(N)CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccc(CCC(=O)OC)cc2)cc1 +c1ccc(COc2ccc(CNCCCCCCCCCCNCc3ccc(OCc4ccccc4)cc3)cc2)cc1 +Fc1ccc(CC(Nc2nc3cc(F)c(F)cc3o2)c2ccccn2)cc1 +CCc1c2s[nH]c(=O)c2c(=O)n2ccc(-c3cc(C)nc(C)c3)cc12 +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(=O)NCc1ccccc1 +O=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1cccc(CCc2ccccc2)c1 +CC(C)(C)ONC(=O)c1cc(NCc2cc(O)ccc2O)ccc1O +O=C(O)c1nc2c(O)nc3cc(C(F)(F)F)c(-n4ccnc4)cc3n2n1 +CC(=O)c1ccc2c(c1)C(NC(=O)c1ccc(F)cc1Cl)C(O)C(C)(C)O2 +Clc1ccc(N2CCN(CCc3cc4ccccc4o3)CC2)cc1 +CC(C)c1nnc2ccc(-c3ocnc3-c3cccc(Cl)c3)cn12 +CN(C(COCc1ccccc1)C(=O)NC(C=O)Cc1ccccc1)S(C)(=O)=O +COc1cc(C2C(C#N)=C(N)Oc3c2ccc(N)c3N)cc(Br)c1OC +CCP(=O)(O)C(C(=O)NC=Cc1ccc(F)c(F)c1)c1csc2ccc(Cl)cc12 +Cc1c(-c2nnc(C3(c4ccc(Cl)cc4)CC3)o2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +Cc1cc(Cc2nc3n(n2)Cc2c(C)ncn2-c2ccc(Br)cc2-3)on1 +Cc1cccc(NC(=O)NCC=C(c2ccccc2)c2ccccc2)c1 +COc1cc(C=CC(=O)NCCCCNc2c3c(nc4ccccc24)CCCC3)ccc1OCCCCCCO[N+](=O)[O-] +COc1ccc(Nc2nc(Cl)cn(C(C)C3CC3)c2=O)c(OC)n1 +COc1ccc2c(=O)c(C(=O)NC3CCCCC3)cn(CCN3CCOCC3)c2c1 +CC(N)CNc1nc(-c2cn[nH]c2)nc2sc3c(c12)CCCC3 +CC(C)c1cc(Nc2ccc(C#N)c(Cl)c2)ncc1C(=O)NCC1CCOCC1 +CC1(F)C(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)OC1n1ccc(=O)[nH]c1=O +O=C1c2c(nnn2Cc2ccc3ncccc3c2)CCN1c1ccccc1 +Cc1csc(Nc2ncc(Sc3ccccc3)cc2OCc2ccccc2)n1 +COC(=O)NC1CCN(c2cc(C#N)cc(Nc3nc(NC4CC4)c4ncc(C#N)n4n3)c2Cl)CC1F +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4ccncc4)o3)cc2Cl)CS1(=O)=O +COc1ccccc1-c1cn2c(-c3ccc(Cl)cc3)c(CN)c(C)nc2n1 +Cc1cc(C)n2nc(CSc3nc(-c4ccccc4)cn3C)nc2c1 +N=C(NC(=N)N1CCN(C(=N)NC(=N)Nc2ccc(Br)cc2)CC1)Nc1ccc(Br)cc1 +CC(C)(C)C(=O)C(=O)N1CCCC1C(=O)OCCCc1ccccc1 +O=C(C(=O)N1CCN(C(=O)c2ccno2)CC1)c1c[nH]c2cccc(F)c12 +O=c1[nH]c2ccccc2n1CCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +COC1Cc2ccccc2C1Nc1ncnc(NC2CC(O)C(COS(N)(=O)=O)C2)n1 +COc1ccccc1N1CCN(CCC(Oc2ccc(NC(=O)c3ccccc3OCCCC(=O)O)cc2)c2ccc(C)cc2)CC1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(CC(=O)NCCO)c4ccccc43)CC2)C(C)C)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)F)n1)c1cc(F)c(-c2cnn(C)c2)cc1F +O=C(O)c1c[nH]c2cc(F)c(-c3ccc(OCCC4CCOC4)cc3)c(F)c12 +NS(=O)(=O)Nc1ccc(NC(=O)NC2CCCCC2)cc1 +COc1cc2nc(SCC(C)C)n(CCCn3ccnc3)c(=N)c2cc1OC +O=C(c1cnccn1)N1CCN(CCCNc2nnc(-c3ccccc3)c3c2cc2ccccn23)CC1 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+COc1nc2ccc(C(O)(c3ccc(Cl)cc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 +Cc1ncc(Cl)cc1C(=O)NC1CCC(CN2C(=O)C3(CC3)c3cc(F)ccc32)CC1 +Cc1cc(O)c(-c2ccc(C(CN)C(C)C)cc2)c2c1[nH]c(=O)c1sccc12 +CS(=O)(=O)C(C(=O)NCCS(=O)(=O)c1ccc(F)cc1)c1nc2ccc(-c3ccnc(F)c3)cc2s1 +CC1(C)CC=C(c2cc(C3CC4(CO)CCC(CO)(C3)O4)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +CN(C)CCNC(=O)c1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +COC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)ccn2)c1 +Cc1cccc(-c2oc(C)nc2C(=O)Nc2cnn(Cc3nc(C4(O)CC4)co3)n2)c1 +COc1cc(OC)cc(C(=O)N2CCC(N3CC(CC#N)(n4cc(-c5ncnc6[nH]ccc56)cn4)C3)CC2)c1 +Cc1c(C(=O)Nc2ccc(S(=O)(=O)N(C)C3CCN(C)CC3)cc2)oc2c(Cl)cccc12 +Cc1cccc(C(=O)N2CCC(N3CCC(Cc4ccc(C(=O)NC(C)C)cc4)CC3)CC2)c1N +COc1cc2ncnc(C#CC(C)(O)Cc3ccccc3)c2cc1OC +CC(NC(=O)c1cnn(C)c1N)c1ccc(CN2CCc3cc(OCC4CC4(F)F)ccc3C2)cc1 +CCC=CCOC(C)C1=CC(C)(C)Nc2ccc(-c3ccccc3OC)cc21 +CCOc1ccc2c(c1)cc(C(=O)NCCCCCC(=O)Nc1ccccc1N)n2C +Cc1ccc(CCCC(CP(=O)(O)O)C(=O)NC(CC2CCCCC2)C(=O)NCCc2ccccc2)cc1 +Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CC[N+](C)([O-])CC4)ccc3OC(F)(F)F)ncc1CC2 +COc1cc(Cl)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CCCCCCCCCCC(=O)C1CCC(C2CCC(C(=O)CCCCC(=O)CCCCCCCC3=CC(C)OC3=O)O2)O1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(OCC)cc1 +CN1CCC(c2cc3c(-c4nc(NCc5ccccc5)ccc4Cl)ccnc3[nH]2)CC1 +CCC(c1ccc2c(c1)CCO2)N(Cc1ccc(OCCN2C(=O)CN(C)C2=O)c(OC)c1)CC1CCC(C(=O)O)CC1 +CCc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +N#Cc1ccc2[nH]c(-c3ccc(F)cc3)c(CCCC(=O)NS(=O)(=O)c3ccccc3)c2c1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2cccnc2)CC1 +CCC1(c2cccs2)OCC(=O)Nc2ccc(-c3ccc(F)c(Cl)c3)cc21 +O=C(Nc1ncc(F)s1)C(CC1CCOCC1)n1ncc2c(S(=O)(=O)C3CC3)cccc21 +COc1c(OCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)cc(C)nc1C +CNC(=O)c1cc(-c2ccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)cc2)ccn1 +CC(C)(Oc1ccc(S(C)(=O)=O)cc1)C1OCC(CC=CCCC(=O)O)C(c2cccnc2)O1 +COc1ccc(-c2nc3c(c(Nc4ccc(CC(=O)O)cc4)n2)SCCC3)c(F)c1F +O=C(NC1CC1)c1ccc2c(=O)n(C(CC3CCCCC3)C(=O)Nc3ncc(Cl)s3)cnc2c1 +N#Cc1cccc(Cc2ccc(C(=O)NCCc3c[nH]c4ccc(Cl)cc34)cc2)c1 +CCOC(=O)C(CC)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2nc(OCCCN3CCCCC3)cc2c1=O +CC(=O)OCC1C2CCC(C)C1(C)CCC(C)=CCCC1(C)OC1C2=O +Cc1nc(C)c(C(=O)N2CCc3cc4ccnc(N5CCN(C)CC5)c4cc32)o1 +CC(=O)Oc1c2c(c3ccccc3c1OC(C)=O)OC(C)(C)C=C2 +CNc1nc(C2CC(F)(F)CN2C(=O)C(O)C(O)C(=O)NC(C)c2ccc(-n3cccn3)cc2)cs1 +COc1cc2c(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)ncnc2cc1OCCCCCn1ccnc1[N+](=O)[O-] +[Li]OC(=O)c1ccc(C(C)NC(=O)C2CCCN2Cc2ccc(C(F)(F)F)cc2)cc1 +Cc1cn(C2CCCN(C(C)c3ccc(C(=O)O)c(Oc4cccc(Cl)c4)c3)C2)c(=O)[nH]c1=O +Fc1ccccc1C1CCN(Cc2ccn3c(CC4CC4)nnc3c2C(F)(F)F)CC1 +NC(CNC(=O)Nc1cccc(S(=O)(=O)O)c1)C(=O)O +N#CC1CCCCC1n1cc(C(N)=O)c(Nc2ccc(OC(F)F)cc2)n1 +COC(=O)c1ccc(CSc2nc3ccccc3c(=O)n2-c2ccccc2)o1 +O=S(=O)(NCCCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc2ncccc2c1 +CN1CCN(c2ccc(OCc3ccccc3)c(NCc3ccco3)c2)CC1 +CN(C)CCCn1c(SCC(=O)N2c3ccccc3Sc3ccccc32)nc2ccccc2c1=O +COc1ccc2nc(C(C)C)c(C=CC3CC(O)CC(=O)O3)c(-c3ccc(F)cc3)c2c1 +CC(C)N(c1cccc(N2CCN(C)CC2)c1)S(=O)(=O)c1cccc2ccccc12 +CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)nc(CNC)cc21 +CC1(C)CN(c2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)c2c(O)ccc(-c3cc(F)cc(F)c3)c21 +NC1=NC(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)(C(F)(F)F)C2CC2O1 +CC#Cc1cncc(-c2cc(Cl)c(C3(C)CC(c4c(C)noc4C)SC(N)=N3)s2)c1 +CCC(C)NC(=O)c1nc(-c2cccc(F)c2)cnc1N +O=C(NC1CCC(Cn2ccc(N3CCNC3=O)n2)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1cccc(C(=O)N2CC3CC(Nc4ccc(C(F)(F)F)cn4)C2C3)c1-n1nccn1 +CCOC(=O)Cc1ccc(OC(=O)CCCNC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 +O=C(c1ccc(CO)cc1Cl)c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12 +CC(C)CC(NC(=O)c1cc2ccccc2o1)C(=O)NC1CCC(C)N(S(=O)(=O)c2ccccn2)CC1=O +CC(F)(F)c1cccc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c1 +CC(C)CS(=O)(=O)c1nc(C(=O)N2COCC2(C)C)ccc1C1CC1 +COc1cccc(C(=O)NCc2nnc(S)n2-c2ccc(Cl)c(Cl)c2)c1 +CNC(C)C(=O)Nc1ccc2c(n1)OC1(CCCC1)C(=O)N2c1ccc(Cl)cc1 +Cc1nnsc1C1=NNC(=O)C1=Cc1cn(C)c2cccc(Br)c12 +CC(C)CC(NC(=O)C(=Cc1ccccc1)CN1CCC(C)(c2cccc(O)c2)C(C)C1)C(=O)O +CC(C)CC(O)c1ccccc1N1CCN(C(=O)C(N)Cc2ccc(Cl)cc2Cl)CC1 +N=C(N)NCCCC(=O)NCCc1ccc(S(N)(=O)=O)cc1 +CC(C)SCc1ccc2c(c1)c1c3c(c4c(c1n2CCCO)Cc1ccccc1-4)C(=O)NC3 +O=C(c1ccco1)N(c1cc(Cl)ncn1)C1CCN(CCc2ccccc2)CC1 +O=C(c1ccc(N2CC(F)(F)C2)c(OCC2CC2)n1)N1CC2CC1CS2 +Fc1cc(Cl)ccc1C(NC1CCN(Cc2ccc(C(F)(F)F)cc2)CC1)c1cccnc1 +CC(C(=O)NCc1ccc(C(=O)O)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 +Cn1c(-c2ccc(-c3ccc(Cl)nn3)cc2)nnc1C1(c2ccc(Cl)cc2)CCC1 +O=C(NNc1cccc(F)c1)C12CC3CC(CC(C3)C1)C2 +CCON=C(c1ccc(F)c(F)c1)c1ccc(CN2CCC3(CC2)OCc2cc(F)ncc23)cn1 +CCOc1cc2cc(-c3c(C)nc(NCc4cc(OC)cc(OC)c4)nc3NC3CC(CO)C(O)C3O)oc2c(C)n1 +O=[N+]([O-])c1cc(NCc2cccc(I)c2)c2ncn(C3OC(CO)C(O)C3O)c2n1 +Nc1c(-c2nc3ccccc3[nH]2)c(O)nc2cnccc12 +CC(C)C(O)Nc1nc(Nc2cccc(-c3cncnc3)c2)c2ncn(C(C)C)c2n1 +CCC(C)C(CN(CC(=O)NC(CCSC)C(=O)OC)Cc1cccc2ccccc12)NCC(N)CS +COC(=O)c1ccc2[nH]c3c(N4CCN(CCc5ccc(F)c(F)c5)CC4)ncnc3c2c1 +Cc1cc(OCCCS(C)(=O)=O)cc(C)c1-c1cccc(COc2ccc(OCC(=O)O)cc2)c1 +CCC(C(C)C)C(O)C(O)C(C)C1CCC2C3CC(=O)C4(O)CC(F)CCC4(C)C3CCC12C +O=C1C(=O)N(CC(CO)NCCCCNc2ccnc3cc(Cl)ccc23)c2ccccc21 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+COc1ccc2c(c1)C(=O)N(CC1(c3cc4cnc(C)cc4o3)NC(=O)NC1=O)C2 +Clc1cc(Nc2ncnc3[nH]nc(OCCN4CCOCC4)c23)ccc1OCc1ccccn1 +CCOC(=O)CNC(=O)C(CC(=O)Nc1ccc(Br)cn1)NC(=O)c1ccc(-c2ccccc2S(N)(=O)=O)cc1 +COC(=O)N(C)C1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +CC(C)(C)c1ccc(CN2CCC3c4ccccc4CCC3C2)cc1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccccc3)o2)C(C)OC(C)=O)c(C)c1Cl +Cc1c(C(=O)NCCC(=O)O)cn2c1C(=O)N(CCC1CCNCC1)CC2 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccc(N4CCOCC4)cc3)cc12 +CC(NC(=O)c1nn(-c2ccc(Cl)cc2)c2c1CCCC2=Cc1ccc(Cl)cn1)c1ccccn1 +Cn1c2c(c3cc(S(=O)(=O)n4ccc5c(F)cccc54)ccc31)C1CCC(C2)N1 +CC1(C)C2CC=C(CN3CCC(NC(=O)Nc4cccc(OC5CCOC5)c4)CC3)C1C2 +Nc1ncc2c(n1)-c1c([nH]c3ccc(Br)cc13)CCC2 +CC1NC(c2cc(C#N)ccn2)=NC1(c1ccc(F)cc1)c1ccc(F)cc1 +CC(C)Cn1c(C(=O)N(C)C)cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(Cl)c21 +COc1nc(-c2ccccc2Cl)cc2nc(-c3c4c(nn3C)CCC43CCCCC3)[nH]c12 +CNC(=O)C1OC(n2cnc3c(Nc4ccc5c(c4)C(C)(C)N([O])C5(C)C)ncnc32)C(O)C1O +Cc1ccc(-c2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)c(C)n1 +CC(C)N(CC(O)COc1ccc(OCc2ccccc2)cc1C(=O)CCc1ccccc1)C(C)C +O=C(NC1CCN(Cc2ccccn2)CC1)C(O)(c1ccccc1)C1CCCC1 +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)N(CC)CC)c3cccc(Cl)c3)CC2)c(F)c1 +Cc1nn2c(O)c3c(nc2c1-c1ccc(F)cc1)CCCC3 +c1ccc(N=c2sc(-c3ccccc3)cn2CCCCCCn2cc(-c3ccccc3)sc2=Nc2ccccc2)cc1 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5ncco5)cc4)nccc3c2Cl)CS1(=O)=O +N#Cc1ccc(N2N=C3c4ccc(C(=O)O)cc4CCC3C2C2CCCC2)cc1 +COc1ccc(S(=O)(=O)N(CC(=O)Nc2cccc(Cl)c2C)c2ccc(C)cc2)cc1OC +CCCCCCOc1c(-c2ccc(O)c(O)c2)oc2cc(OC)c(OC)c(OC)c2c1=O +CCOc1ncccc1-c1noc(C2CCN2C(=O)c2cc(OC)c(F)cc2-n2nccn2)n1 +C=CC1CC(C(=O)O)=CC(OC(C)C)C1NC(C)=O +N=C1c2ccc(OC(F)(F)F)cc2CN1Cc1cccc2ccoc12 +CC(C)(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1nc(-c2ccccc2)c(Cc2ccccc2)s1 +O=C1c2ccccc2C(=O)N1CCCCN1CCC2C(C1)c1cc(F)ccc1N2c1ccc(F)cc1 +COCCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2ccccc2)CC3)n1 +O=C(c1ccc2occc2c1)N1CCC(N2C(=O)OCc3ccccc32)CC1 +Cc1ccc2nc3c(c(Nc4ccc(N(C)C)cc4)c2c1)CCC3 +Cc1nc2ncccc2cc1-c1ccc2cc(CCN3CCCC3C)ccc2n1 +CCn1c(=O)c2c(nc3n2CCCN3c2ccc(F)cc2)n(CC)c1=O +CCOc1ccc(F)c(-c2c[nH]c(-c3cccc(CN4CCCCC4)c3)n2)c1 +Cc1n[nH]cc1-c1cc2nc(CN3CCCCC3)[nH]c(=O)c2s1 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CN(c4ccc(Cl)cn4)C5)cn3)n2)s1 +Cc1ccc(-c2c(CN)c(CC(C)C)nc3ccc(OCCC(=O)O)cc23)cc1 +Cc1ccc(C2=NN(C(N)=S)C(c3ccc(C)cc3)C2)cc1 +CNC(=O)C=C1COc2c1ccc(OS(=O)(=O)c1ccc(OC)cc1)c2C +N#CNC(=NCCCCCCCOc1ccc(Cl)cc1)Nc1ccncc1 +CCCCCCCCCCCCn1nnc(C(NC(=O)c2ccccc2)c2ccccc2)n1 +CC(=CC(=O)O)c1cc2cccc(-c3cc(C(C)C)cc(C(C)C)c3OCC(F)(F)F)c2o1 +[N-]=[N+]=NC1CC(n2cc(-c3cc(CO)on3)c(=O)[nH]c2=O)OC1CO +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NCC(C)(C)N +O=C1COc2ccc(Cl)cc2CNC(=O)C2CCCN2C(=O)C(C2CCCCC2)NC(=O)CCCCN1 +CCCCCOc1cc2ccccc2cc1C(O)CC#CCCCC(=O)OC +O=c1cc(N2CCOCC2)nc(Cc2nc3cc(C(F)(F)F)ccc3[nH]2)[nH]1 +NCCOc1cccc2c1c1cccc3c1n2C(c1ccccc1)CO3 +Cc1ccncc1-c1cc2cnc(NC(=O)C3CC3)cc2cn1 +COc1cc(C)c(C(=O)O)cc1-c1ccc(C#CCO)s1 +CC1CCc2cc(C(=O)N(C)CC(F)(F)F)ccc2N1C(=O)c1ccc(O)cc1O +Cc1cnn(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C(F)(F)F)n2)n1 +CCCc1nc(C)c(C(=O)O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +N#Cc1ccc2c(C(=O)NCc3ccc(F)cc3)c(O)n(O)c(=O)c2c1 +CNC(=O)CC(C)(NC(=O)c1cc(OC(C)C(F)(F)F)c(C2CC2)cn1)C1CC1 +CCCN(Cc1c(C(F)(F)F)nc2n(-c3c(C)cc(C)cc3Cl)c(Cl)cn12)CC1CC1 +Cc1cc(C)c(Oc2nc(NC3CCN(Cc4ccc(C(N)=O)cc4)CC3)nc3ccsc23)c(C)c1 +O=C(NNc1ccc(F)cc1)C(=O)c1c[nH]c2ccccc12 +CC(=CCCP(=O)(OCOC(=O)C(C)(C)C)OCOC(=O)C(C)(C)C)CO +CCN1CC2(CCN(C(=O)c3nn4c(C(F)(F)F)cc(C5CC5)cc4c3Cl)CC2)OC1=O +[C-]#[N+]C1C(C)=NC(C(F)F)=C(C#N)C1c1cc2c(N)nccc2o1 +CNC(=O)Cc1ccccc1CNC(=O)c1nc(N2CCCCS2(=O)=O)c2cccnc2c1O +Nc1cnc(-c2ccc(C3CCC3)c(OCc3ccc(CC(=O)O)cc3)c2F)cn1 +COC(=O)c1ccccc1S(=O)(=O)N1CCCC(Cn2ccnc2)C1 +N#Cc1c2c3ccc(Sc4ccc(Br)cc4)c4cccc(c-2nc1=O)c43 +O=c1c2c([nH]c3ccc(-c4ccc(COc5ccccc5)cc4)cc13)CCSC2 +OCC1CCCCN1CCc1ccc(Nc2nc(-c3cccc(Cl)c3)cs2)cc1 +O=C(NCC(=O)N(CCO)C1CCS(=O)(=O)CC1)c1cc2cc(Cl)ccc2[nH]1 +CCC(NC(=O)c1ccc2c(c1)ncn2Cc1ccc(Cl)cc1)c1ccccc1 +CCOC1CCC(CS)(C(=O)NC(Cc2ccccc2)C(=O)NC)CC1 +COc1cc(C=C(C#N)c2nc3ccccc3[nH]2)ccc1OCC(=O)Nc1ccccc1C(C)C +COc1cc(NC(=O)N(C)c2cc(Nc3ccc(N4CCN(C)CC4)cc3)ncn2)c(Cl)c(OC)c1 +CCc1ccc(-c2ccc(C(=O)N(C)C3CCN(C(=O)N4CCC(N5CCCCC5)C4)C3)cc2)cc1 +COc1ccc2c(c1)c(C(C)N(O)C(N)=O)c(C)n2C(=O)c1ccc(Cl)cc1 +O=C(CC1CCOCC1)N1CCC(Oc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +CN1CCC(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)(S(C)(=O)=O)CC1 +COC(=O)c1c(NCC(OC)OC)n(-c2ccccc2)c(=S)n(-c2ccccc2)c1=O +Nc1ccc2cc(NCCc3ccccc3)cc(Nc3ncccn3)c2n1 +N=C(N)c1ccc(CNC(=O)C2CCCN2C(=O)CCc2ccccc2)cc1 +CCC1CN(C2CC3(C)C(CCC4C5CCC(C(C)=O)C5(C)CC(=O)C43)CC2O)CCO1 +COC(C)(C)c1nnc2cc(-c3cc(C(=O)NC4CC4)cc(F)c3C)ccn12 +CC(O)(C#Cc1ccc2c(c1)-c1nc(C(N)=O)cn1C1CC2C1)c1nc[nH]n1 +COc1ccc(-n2c(SCC#N)nc3sc4c(c3c2=O)CCCC4)cc1 +NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)CCc1cc(-c2ccccc2)on1 +O=c1c2cccnc2ncn1Cc1nc(CC(F)c2ccc(Cl)cc2)no1 +CC(C)c1cc(Oc2c(F)cc(NC(=O)C(=O)O)cc2F)ccc1O +Cc1ccc2c(-c3nnc(SCCCN4CCc5ccc6nc(C(C)(F)F)oc6c5CC4)n3C)cccc2n1 +CC(C)OCC(Oc1ncnc2c1cnn2-c1ccccc1Cl)C(=O)Nc1ccc(C#N)cn1 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+COc1ccc(-n2nc(C(F)(F)F)cc2C(=O)Cc2ccc(-c3ccccc3CN3CCC(O)C3)cc2)cc1 +O=C(Nc1cc(CN2CCCC2)[nH]n1)Nc1cccc2c1C1CCCN1C2=O +c1ccc2ncc(N3CCC(c4nc(C5CCCCC5)no4)CC3)cc2c1 +Cc1nc2cccnc2n2c(-c3cc(OC4CCOCC4)ccc3Cl)nnc12 +O=C(O)C1CCN(C2CCC3(C2)C(=O)c2cc(F)ccc2Sc2ccccc23)CC1 +Nc1n[nH]c2cccc(-c3ccc4c(C(=O)Nc5cc(Cl)cc(Cl)c5)cccc4c3)c12 +NCC1OC(OC2C(N)CC(N)C(O)C2OC2OC(CO)C(OC3OC(CN)C(O)C(O)C3O)C2O)C(N)C(O)C1O +C[n+]1ccc(Nc2ccc(Cc3ccc(N(CCO)CCO)cc3)cc2)c2ccccc21 +O=c1ccn(CC(CCO)COC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1 +COc1cc2c(NC3CCN(C4CC4)CC3)nc(N3CCS(=O)(=O)CC3)nc2cc1OCCCN1CCCC1 +CN1C(=O)NCc2c(NC(=O)NC3CC(C)(C)Oc4cc(C(F)(F)F)ccc43)cccc21 +CC1(C)CC1C(=O)NC(=CCCCCCSCC(N)C(=O)O)C(=O)O +Cc1cccc(COc2ccc3c(c2)-c2nnc(C)cc2C3=O)c1 +COc1cc(-c2cc(=O)c3c(O)c(OC)c(OC)c(OC)c3o2)ccc1O +CCc1cc(NC(=O)NCCN2CCC(O)(Cc3ccccc3)CC2)c2sccc2n1 +NC1CCN(S(=O)(=O)c2ccc3[nH]c(-c4cc5ccccc5nc4O)cc3c2)C1 +CCCCN(CCCC)C(=S)NN=Cc1c(C)nn(-c2ccccc2)c1O +N#Cc1ccc(C(c2ccc(C#N)cc2)n2ccnc2)cc1 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+Nn1c(S)nnc1-c1sc(NC(=O)CCl)cc1-c1ccccc1 +CC(SC(CCc1ccccc1)C(=O)O)C(=O)N1C(C(=O)O)CC2CCCCC21 +CC(C)(CC(=O)N1CCc2ccccc2C1)NCC(=O)N1CCCC1C#N +O=C(CCCCCCNC(=O)c1cnc(N2CCCNCC2)nc1)NO +CC(C)Nc1c(C(N)=O)nnc2ccc(-c3ccncc3)cc12 +CN1C(=N)NC(C)(c2sc(-c3cccc(-c4ncno4)c3)cc2F)CS1(=O)=O +CC1(C(=O)O)CCC(CC(=O)N2CCc3c(n(Cc4ccc(F)cc4)c4ncccc34)C2)CC1 +CC(C)c1c(Cc2c(F)cccc2Cl)nc(SCC(=O)c2ccccc2)[nH]c1=O +CCCCCN(C(=O)c1ccc(C)cc1)C(C)c1nc2ccccc2c(=O)n1-c1ccccc1CC +O=C(c1cc(CO)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2)N1CCCC1 +CCCCC#Cc1nc(NCc2cccc(Cl)c2)c2ncn(C3SCC(O)C3O)c2n1 +Cc1ccc(-c2ccc(N(CC(N)CC(C)C)C(=O)C3CC3c3ccccc3)cc2)cc1 +C=CC(=O)Nc1cc2c(Nc3ccc(F)c(F)c3F)ncnc2cc1OCC1CCN(C(C)=O)CC1 +O=C1CCC(c2ccc(OCCCN3CCCC3)cc2)=NN1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(c3cccc(C(N)=O)c3)CC2)ncc1[N+](=O)[O-] +CCOC(O)=C1C(COCc2cc(=O)n(C(C)C)c(N)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +CS(=O)(=O)c1ccc(-n2cc(C(F)(F)F)nc2-c2ccccn2)cc1 +COc1cc(OCc2csc(C3(F)CCOCC3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CCN1CCC(N=CC(C=N)c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)C1 +COc1cc(C)nc(OC)c1NC(=O)N(Cc1ccc(Oc2ccc(F)cc2)cc1)C1CCCCCC1 +COC(=O)C1C(=O)C2=C(CC1C)NC(=O)CC2c1ccc(Cl)cc1Cl +CC(C)n1ncc2cc(NC(=O)c3ccc4cc5n(c4n3)C(C)CCNC5=O)cnc21 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NC4CCCC4)nc23)N1 +COc1cc(C(=O)Nc2cnn(Cc3c(C)noc3C)c2)ccc1O +CCCCCCCc1ccc(NC(=O)Nc2c(C(C)C)cccc2C(C)C)cc1 +CN(C)S(=O)(=O)c1ccc2c(c1)C(=Cc1[nH]c3c(c1CCC(=O)O)C(=O)CCC3)C(=O)N2 +Cc1cc(Nc2ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n2)c(OC(C)C)cc1C1CCN(CC(F)F)CC1 +Cc1nn(-c2ccc(Cl)cc2)c(O)c1C(c1cccc(O)c1)c1c(C)[nH]n(-c2ccc(Cl)cc2)c1=O +Cc1ccc2c(=O)c(C(=O)NC3CCCCC3)cn(Cc3ccc(F)cc3)c2n1 +C=C(COC)C1CCC2(COC(=O)n3ccnc3)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCCN(CC3CC3)C2=O)CC1 +COC(=O)N1CCC(N(C)C(=O)CN(CC(=O)NCCN2CCCC2)c2cc(Cl)ccc2Oc2ccc(Cl)cc2)CC1 +Cc1ccc(C)c2c1NC(=O)C2=NNC(=O)CCc1ccc(O)cc1 +CN(c1ccc(Oc2ccccc2)cc1)S(=O)(=O)c1ccc(Cl)cc1 +CCOc1ccccc1C(=O)N1CCN(c2cccc(Cl)c2)CC1 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+Nc1ncnc2c1c(-c1ccccc1)cn2-c1ccc(CO)cc1 +Cc1cccc(C2(O)CCN(C(c3ccccc3)c3ccccc3)CC2)c1 +CCCn1cc(-c2cn3ncc(C(N)=O)c(NC4CN(C(=O)C5(C#N)CC5)CC4CC)c3n2)cn1 +COC(=O)c1ccc(-c2ccc(OCCCCOc3ccc4cccc(CCNC(C)=O)c4c3)cc2)cc1 +Nc1ncc(-c2nc(N3CCOCC3)nc3c2CCN3C2CN(S(=O)(=O)C3CC3)C2)cn1 +CCC(O)(C#Cc1cn2nc(-c3ccco3)nc2c(N)n1)CC +CC(C)CN(Cc1ccc(N2CCN(C(=O)C3COC3)CC2)cc1)S(=O)(=O)Cc1ccccc1 +OC1CCN(Cc2ccc(I)cc2)CC1N1CCC(c2ccccc2)CC1 +O=C1CCc2ccc(NC(=O)NC3CCc4cc(Cl)ccc43)cc2N1 +CCCCCCCCC[n+]1ccc2c(c1)C1C(CC2)CCN1C +O=C1NC(C(=O)O)Cc2ccc(cc2)OCC=CCOc2cccc(Cl)c21 +Cc1c(F)c(Oc2cccc(OC(C)C)c2)nc(Oc2cccc(C(=N)N)c2)c1F +CCOc1ccc(CCNC(=O)C(CC(=O)O)NC(=O)CCCOc2ccc(C(=N)N)cc2)cc1 +COc1cc(-c2c(Cl)ncn2-c2ccc(S(C)(=O)=O)cc2)ccc1C +COCCN(C)c1ccc(-n2c(O)nnc2-c2cc(C(C)C)c(O)cc2O)c[n+]1[O-] +Cc1c(N2CC3CCC(C2)O3)nc2n(c1=O)CCC(C(F)(F)F)N2CCCc1ccccc1 +CCOC(=O)C1CCCN1C(=O)c1cc(C(=O)NC(CC)c2ccccc2)c2n1CCOC2 +NCc1ccc(C(=O)NC(c2ccc(Cl)cc2)c2nc3ccc(-c4cn[nH]c4)cc3c(=O)[nH]2)cc1 +CNc1nc2[nH]c(-c3cccc(N(C)CCOC)n3)cc2c2c1ncn2C +Clc1nc2c(NCc3ccccc3)nc(N3CCNCC3)nc2nc1N1CCCC1 +CCOC(=O)Nc1cc2c(c(N)n1)N=C(c1cccc(NC(=O)c3ccc(N=[N+]=[N-])cc3)c1)C(C)N2 +N=C(N)c1ccc(C=C2CCC(=Cc3ccc(C(=N)N)cc3)C2=O)cc1 +CCC(C)(C)NC1C(=O)C(=O)C1CNc1c(C)cc(Cl)cc1Cl +COC(=O)CC1CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(CC2CC2)C1=O +COC1CCN(c2ncc(Cl)c(N3CCC(Oc4ccc(C(C)NC(C)=O)cc4)C3)n2)CC1 +CN1C(=O)C2(CC(C)(C)Sc3ccc(-c4cncc(Cl)c4)cc32)N=C1N +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2N)cc1 +CCC(CO)Nc1nc(NCc2ccncc2)c2ncn(C(C)C)c2n1 +CC1(O)CCCN(S(=O)(=O)c2ccc(C(C)(C)C)cc2)CC1 +CC(=O)OCC1C2CC3CCC1N3CC2=Cc1ccc2ccccc2c1 +N#Cc1nc(-c2ccnc(Nc3ccc(CN4CCOCC4)nc3)n2)ccc1N1CCC(O)C1 +Cc1cccc2cc(-c3cn4nc(C(C)(F)F)sc4n3)oc12 +CN1CCN(CC(=O)Nc2cccc3c2C(=O)c2c-3n[nH]c2-c2ccc(N(C)C)cc2)CC1 +CC(C)N1CCN(CCN2CCN(c3ccc(F)c(C#N)c3)C2=O)CC1 +CCC(=NNC(N)=O)c1ccc2ncc(Cc3cc4cnn(C)c4cc3F)n2n1 +Cc1ccccc1-n1nc(-c2c(-c3ccc(F)cc3Cl)nc3ccccn23)ccc1=O +CC(C)(C)OC(=O)N1CCC(OC2CCC(Oc3ccc(S(C)(=O)=O)nn3)CC2)CC1 +CCOC(=O)c1ccc(NC2CCCC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +O=S(=O)(Cc1ccc2c(c1)CCNCC2)c1ccc(-c2ccc(F)cc2)nc1 +Cc1cccc(C)c1-c1nc(C(=O)Nc2cccc(C(=O)O)c2)c(CCC23CC4CC(CC(C4)C2)C3)[nH]1 +NC(Cc1ccccc1)C(=O)NCCOCCOCCNC(=O)c1ccc(S(N)(=O)=O)cc1 +O=S(=O)(c1ccc(Cl)c(Cl)c1Cl)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 +Cc1ccc(CNCCC2(c3ccccn3)CCOC3(CCCC3)C2)o1 +CC(=O)N1CCC(C)(c2ccccc2)c2cc(NC(=O)NCc3cccc(Cl)c3)ccc21 +CCCn1c(=O)c2cn[nH]c2c2ccc(-c3ccncc3)cc21 +O=C1COc2ccc(-c3n[nH]c(C4CCCCN4C(=O)COc4ccccc4)n3)cc2N1 +COc1cccc(NC(=O)C(O)C(N)CC2CCCCC2)c1 +O=C(c1ccccn1)C1CCCN1C(=O)C1CCCN1C(=O)CCCc1ccccc1 +O=C1NC(=S)N(Cc2ccco2)C(=O)C1=Cc1ccc(-c2ccc([N+](=O)[O-])cc2)o1 +Cc1cc(=O)oc2cc(OCc3nnc(SCCN4CCOCC4)n3-c3ccc(Cl)cc3)ccc12 +O=C(Cn1c(-c2ccccn2)nc2ccccc21)c1ccc(Cl)cc1 +Cn1c(=O)c2c(-c3cccc(Cl)c3)n3c(c2n(C)c1=O)C(c1ccc(Cl)o1)NCC3 +Cc1ccc(CCN2CCN(c3cccc4cc(C(=O)N(C)C)oc34)CC2)nc1 +C=C1C(=O)OC2C1CC1(O)C3Cc4ccc(O)c5c4C1(CCN3CC1CC1)C2O5 +CCN(CC)c1ccc(CN(C23CC4CC(CC(C4)C2)C3)S(=O)(=O)c2ccc(C)cc2)cc1 +O=C(O)c1cccc(-c2cnccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 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+COc1ccc(CN2CC3CCN(S(=O)(=O)c4ccc(Cl)cc4Cl)CC3Oc3c(NC(=O)C4CC4)cccc3C2=O)cc1 +Cn1cc(-c2cc(OCCCCC(=O)O)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +O=C(O)CCc1cc(Br)c(OCc2cccc(Cl)c2)c(Br)c1 +CCn1c(Cn2ccc(C(F)(F)F)c(Oc3cc(Cl)cc(C#N)c3)c2=O)n[nH]c1=O +CC1OC(n2cnc3c(N)nc(OC4CCCC4)nc32)C(O)C1Oc1ccccc1 +CCCN(CCC)C(=O)C1=Cc2ccc(C(=O)Nc3cncc(CCc4ccc(OC)cc4)c3)cc2N=C(N)C1 +CCOc1cc(OC2CCNC2)ccc1-c1nc2snc(C3CCCCC3)c2c(=O)[nH]1 +CCCSc1nc(N2CCC(CC(=O)O)CC2)ccc1C(=O)NC1CCCCC1 +Cc1c(Cl)ccc2[nH]c(-c3ncsc3N3CCN(C(=O)Cn4cnc5cccnc54)C(C)C3)nc12 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5cc(C(F)(F)F)n[nH]5)cc4)nccc3c2Cl)CS1(=O)=O +COc1cccc(N2C(CN3CCOCC3)=Cc3cc(S(N)(=O)=O)sc3S2(=O)=O)c1 +CN(C)Cc1cccc(-c2cc3c(-c4cnn(C)c4)ccnc3[nH]2)c1 +O=C(NCCO)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cccc(Cl)c3Cl)c(F)c2)CC1 +COc1c2occc2c(OC)c2c(=O)c(-c3cc(-c4ccc(F)cc4)[nH]c(=S)n3)c(C)oc12 +CC(C)(O)c1cncc(-c2nc3ccc(F)cc3n2C2CC2)c1 +Cc1cccc2c(C(=O)C3CSC(c4cccnc4)N3)c[nH]c12 +O=c1[nH]c(C2CCN(S(=O)(=O)C3CC3)CC2)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +Cn1cnc(S(=O)(=O)NCCOc2cc(C(CN)Cc3ccccc3)ccc2F)c1 +COc1cccc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1OC +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=NC#N)c(F)c2)cn1C(C)C +Cc1oc(-c2c(Cl)cccc2Cl)nc1CN1CCC(C(=O)NCCCN2CC(C)CC(C)C2)CC1 +C#CCOc1ccc2c(c1)n1ncc(I)c1n[n+]2[O-] +CC1CCc2cc(-c3ncnc4cccc(F)c34)ccc2N1C(=O)c1ccc(O)cc1O +CC1CC2CSC(N)=NC2(c2nc(NC(=O)C3CC3)cs2)CO1 +Cc1[nH]c2ccccc2c1CCCN1CCC(c2noc3cc(F)ccc23)CC1 +Cc1ccc2c(c1)nc(CCc1ncc3cccnn13)n2-c1ccccc1 +CC(C)C(C(=O)NC1CCCCC1C(=O)O)N(C)S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(N3CC(CO)C3)c2c1=O +CC1(n2cc(C(=O)c3cncc(NC(=O)Cc4ccc(Cl)cc4)c3)c3cncnc32)COC1 +O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(c2cc([N+](=O)[O-])ccc2F)CC1 +CC(N)(CCc1ccc2c(c1)CCc1c-2noc1-c1noc(-c2ccccc2)c1C(F)(F)F)C(=O)O +CC(C)Nc1cc(-n2ccc3cc(C#N)cnc32)ncc1C(=O)NCC(=O)N1CCN(C)CC1 +Cc1ncccc1NC(=O)c1ccc2c(c1)CCC1CC(OP(=O)(O)O)(C(F)(F)F)CCC21Cc1ccccc1 +CCCS(=O)(=O)NCCOc1ccc2c(c1)C(Cc1ccccc1)C(N1CCC1)CC2 +Clc1cccc(-c2cccc(-n3nnc(-c4ccccn4)n3)c2)c1 +O=C(c1ccc2occc2c1)N1CCOC2(CCN(Cc3ccc(Cl)cc3)CC2)C1 +Cc1cc(Cl)ccc1C1c2c(nn(C3CCN(C)CC3)c2C(C)C)C(=O)N1c1cccc(Cl)c1F +O=C(Nc1ccc(C2=CCN(C(=O)c3cccnn3)CC2)cc1)N1Cc2ccccc2C1 +CNC(=O)c1ccc(NC(=O)Nc2ccc(-c3nc(N4CCOCC4)c4cccnc4n3)cc2)cc1 +Oc1c2cnc3c(c2nn1-c1ccc(OC(F)(F)F)cc1)CCCC3 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(OC(C)C)c2)[nH]1 +CCCCc1cc(OC2CCN(CCS(=O)(=O)CC)CC2)c2ncccc2c1 +Cc1[nH]c(C)c(-c2ccc(Oc3cccc(Cl)c3)cc2)c(=O)c1Br +Cc1cc(N2CCC(N3CCCC3)CC2)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +CC(NC(=O)OCc1ccccc1)C(=O)NC(C)C(=O)NN(CC(N)=O)C(=O)C=CC(=O)NCc1ccc(F)cc1 +C=C1CC(C=CC(C)=CCC2OC(C)C(NC(=O)C=CC(C)OC(C)=O)CC2C)OC(CC(=O)O)C1 +CC(Oc1cc(C(N)=O)nc(-c2ccc(Oc3ccc(C#N)cc3)cc2)n1)C(N)=O +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCN(C(C)(C)C(N)=O)C1 +CC1CCN(c2ncc3cc(F)ccc3n2)CCN1C(=O)c1ccccc1-n1nccn1 +CC(=O)Nc1ccc2[nH]cc(CC(NC(=O)c3ccc4c(c3)nc(-c3ccoc3)n4C3CCCCC3)C(=O)O)c2c1 +CN1CCN(Cc2cn(S(=O)(=O)c3cccc(F)c3)c3ccccc23)CC1 +CCOC(=O)C(=O)Nc1cc(C)c(Oc2ccc3[nH]cc(C(C)C)c3c2)c(C)c1 +Cc1cc(C2CNCCO2)ccc1NC(=O)c1ccc(Cl)nc1 +COc1ccc(C(=O)n2nc(-c3ccco3)nc2N)cc1 +Cn1nc(-c2cnc(N)c(-c3nnc(C(C)(C)C)o3)n2)nc1C1(c2ccccc2)CC1 +Cc1ccccc1NC(=O)N(CCCN1C2CCC1CC(n1c(C)nnc1C(C)C)C2)c1ccccc1 +CCC(C1CC1)n1cc(Cl)nc(Nc2cc(C)c(OC)cc2C)c1=O +CC(C)(O)c1cccn2c(-c3ccnc(NC4CCC(NS(C)(=O)=O)CC4)n3)cnc12 +CC(=O)c1ccc(OCc2ccc(Oc3cccc(-c4nn[nH]n4)c3)cc2)c(C)c1O +CC1CC1C(=O)Nc1snc(-c2ccc3nn(C)cc3c2)c1-c1cccc(C2CC2)n1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)c(F)c2)cn1C(C)C +CCCN(CCC)Cc1c(C(=O)NN=CC(C)=Cc2ccccc2)nnn1-c1nonc1N +CCCCOc1ccc(C(=O)NN2Cc3ccccc3NC2c2ccc(OC)cc2)cc1 +CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCCCC4)ccc31)CN(C1CCCC1)C2 +O=C(CCn1nnnc1-c1ccc2c(c1)OCO2)c1ccccc1 +COc1ccccc1N1CCN(C(=O)CCc2c(-c3ccc(Cl)cc3)n(CCO)c3ccc(Cl)cc23)CC1 +CC(C)CN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCC(F)C4)n3)cc2)C1=O +CC(Nc1nc(Nc2cn(C)cn2)c2[nH]ccc2n1)c1ncc(F)cn1 +CC1(CC(=O)NCc2ccc(-c3ccc(F)cc3)cc2)CC2(CCCCC2)OO1 +CC(NP(=O)(OCC1OC(C#N)(c2ccc3c(N)ncnn23)C(O)C1O)Oc1ccccc1)C(=O)OC1CCC1 +CCOc1ccc(N(CC(=O)O)C(=O)C(C)CS)cc1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2Cl)nc1-c1cc(C(F)(F)F)ccc1F +CNCc1cc(-c2cccnc2F)n(S(=O)(=O)c2ccccn2)c1 +O=C(Nc1ccccc1C(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccno1)OCc1ccccn1 +Cc1ccc(OCC(=O)Nc2cc(-c3nccs3)nc(-c3ccc(C)o3)n2)cc1 +Cc1c(CN(CCc2ccc(Cl)cc2)C2CCN(C(=O)c3c(F)cccc3F)CC2)c(=O)n(-c2ccc(Cl)cc2)n1C +COc1cc(F)ccc1-c1nc(Nc2cc(F)cc(CS(=O)(=NC#N)C3CC3)c2)ncc1F +c1ccc2c3c([nH]c2c1)CC1CCC3N1CCCCc1nccs1 +N=C(N)c1ccc(CNC(=O)C2CCCN2C(=O)C(CO)NS(=O)(=O)Cc2ccccc2)cc1 +CC(C)CCc1nn(-c2ccccc2Cl)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=c1nc(OCC2COc3ccccc3O2)cc2n1CCc1cc(OCc3nnnn3C3CC3)ccc1-2 +Nc1ncc(-c2nc(N3CCOCC3)nc3c2CCN3c2ccc(CN3CCOCC3)cc2)cn1 +O=C(Nc1ccc(C2CCNC2)cc1)Nc1cccc2cccnc12 +CC(=O)Nc1cccc(C2CCN(CCCNc3nc4ccccc4n3-c3cccc(Cl)c3)CC2)c1 +CCCCCCC(Oc1ccc(C(=O)NCCC(=O)O)cc1)C(=O)Nc1ccc(-c2ccc(Cl)cc2Cl)cc1 +N=C(c1ccc(NC(=O)c2cc(C(F)(F)F)nn2-c2cc3ccccc3cc2F)c(F)c1)N1CCCC1 +Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21CCC(F)(F)CC1 +CC1(c2ccccc2)CCN(c2cccc(-c3ccc(F)cc3F)c2)C(=O)O1 +COC(=O)c1coc(CN2CCC(CNC(=O)c3n[nH]c4ccc(OC)cc34)CC2)n1 +NC(=O)CCNC(=O)c1ccccc1SC(=O)NC1CCCCC1 +O=C(Nc1cccc(F)c1)Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)c2ccccc12 +COc1cc2cc(C(=O)N3CC4CC45C3=CC(=O)c3[nH]c(C)c(CN(C)C)c35)[nH]c2c(OC)c1OC +CCNc1cc(-c2c[nH]c(CN=C(NC)NC#N)n2)ccn1 +CC1(C)Cc2nc(N3CCOc4ccc(-c5ccn[nH]5)cc43)sc2C(=O)N1 +CC(C)(C)c1nc(N2CCN(CCCCNC(=O)C3CCC(c4ccccc4)CC3)CC2)cc(C(F)(F)F)n1 +CS(=O)(=O)c1cccc(-c2cccc(-c3cc(C(F)(F)F)nn3-c3ccccc3Cl)c2)c1 +Nc1nc(C(=O)NCc2cccc3cccnc23)c2ccc(F)cc2n1 +Cc1ccc(S(=O)(=O)Nc2cncc(-c3cnc(N)nc3)c2)cc1 +COCC(NC(=O)Nc1cc2[nH]nc(OCc3ccccc3)c2cn1)c1ccccc1 +COc1cccc(NC(=O)N2CCCC(CCN3CCC(Cc4ccc(F)cc4)CC3)C2)c1 +CC(C)(C)N(NC(=O)c1ccc(F)cc1)C(=O)c1ccccc1Cl +CC(C)(C)c1ccc(S(=O)(=O)c2ccccc2Cl)cc1 +CC(C)CN(Cc1cc(Br)c2c(c1)OCCCO2)C(=O)C(C)CNCc1ccccc1 +COc1cccc(CSc2nc(Cc3ccccc3)c(C)c(=O)[nH]2)c1 +Cc1cc(Nc2nc(N3CCN(C(=O)c4ccccc4C)CC3)nn3cccc23)n[nH]1 +COc1cc(-c2cc(C)cs2)ccc1S(=O)(=O)Nc1cccc(N2CC(C)NC(C)C2)c1 +Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(F)cc1 +O=C(CCCCCc1ccccc1)c1nc2ccc([N+](=O)[O-])cc2o1 +CC1CN2c3c(cc4c(N5C(=O)OCC5C(O)CO)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CCOC(=O)C(C)NP(=O)(OCC1OC(c2cnc3c(N)ncnn23)C(C)(F)C1O)Oc1ccccc1 +O=C(COc1ccc2cc(C(=O)Nc3ccccc3)ccc2c1)NCc1ccc(OP(=O)(O)O)c(OP(=O)(O)O)c1 +CC(=O)N1CCN(C(=O)C=Cc2ccc(Sc3ccc(Cl)cc3Cl)c([N+](=O)[O-])c2)CC1 +OCCC1CCCCN1CCCCn1cnc2c(O)nc(Nc3ccccc3)nc21 +Cc1c[nH]c2ncnc(N3CCN(C(=O)Nc4cccc(C(=O)NCCO)c4)C(C)C3)c12 +CCOc1ccc(N2CC(CN3CCC(O)(c4ccc5c(c4)OCO5)CC3)OC2=O)cc1 +Cc1cccc(-c2c(O)nc3cc(Cl)c([N+](=O)[O-])cc3c2OCCC2CCCCN2)c1 +COc1cc(CNCc2ccncc2)ccc1OCc1cnc(Cl)c(Cl)c1 +c1ccc2c(c1)ccc[n+]2CCCCCC[n+]1cccc2ccccc21 +COc1ccc(COc2ccc(-c3ccn4c(CC5CC5)nnc4c3C(F)(F)F)cc2)cn1 +C=C(CO)COC1(c2ccc(Cl)cc2)c2ccccc2C(=O)N1Cc1ccc([N+](=O)[O-])cc1 +NC(=O)CCNc1ncc2c(n1)c(Nc1cccc(Cl)c1)nc1cc(C(=O)O)ccc12 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+COc1ccc(-c2nnc(N3CCN(c4ncc(C(C)(C)O)c(C(F)(F)F)n4)CC3)c(C)c2C)cc1 +NS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)cc1 +CCNC(=O)Nc1ncc2cc(-c3cc(F)ccc3C)ccc2c1Cl +O=C(NC(c1ccc(Cl)cc1)c1cccnc1)c1ccc(Cl)cc1 +O=C(O)c1ccc(CCCN2C(=O)CCC2CCC(O)Cc2ccc(F)cc2)s1 +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(CCc3ccoc3)CC2)cc1 +O=C(O)c1cc(-c2cccc(C(F)(F)F)c2)ncn1 +Cc1cn(-c2ccc3n(c2=O)CCN(C(C)C2CCC(c4ccc(Cl)cc4OC(F)(F)F)O2)C3=O)cn1 +COc1ccc(COc2ccc(-c3cc(C(=O)O)c4cnn(Cc5ccncc5)c4n3)cc2)cc1 +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2[nH]ncc2c1 +COc1ccc(-c2cc(-c3cc(OC)c(OC)c(OC)c3)[nH]n2)cc1 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)Nc2cccc(F)c2C)cc1 +O=c1nc(N2CCOCC2)cc(N(CCCO)Cc2cccc3ccccc23)[nH]1 +CCSc1ccc2ncc(-c3ccnc(Nc4ccc(S(=O)(=O)NCCOC)cc4)n3)n2c1 +O=C1CN(c2ccc(Cl)c(Cl)c2)C(=O)N1S(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(Cn4cccn4)c4ccccc43)CC2)C(C)C)c1 +CC(C)(C)OC(=O)N1CCN(C(=S)SCc2cn(Cc3cc(=O)oc4c(O)c(O)ccc34)nn2)CC1 +O=C(OC12CC3CC(CC(C3)C1)C2)c1cc(N(O)C2CCCO2)on1 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+CC(C)N(CC#CCCC(=O)C(O)(c1ccccc1)C1CCCCC1)C(C)C +NC1CCCN(c2ncncc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)C1 +NS(=O)(=O)c1ccc(Nc2ncnc(Cl)c2[N+](=O)[O-])cc1 +CN(CCCc1ccc2c(c1)C(Cc1cccc(F)c1)C(N)CC2)S(=O)(=O)CC1CC1 +CN1C(=O)N(C)C2(NC(=O)NC2=O)c2ccccc21 +Nc1c2c(nc3c1C(c1ccccc1Br)c1ccc4cccnc4c1O3)CCCC2 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4CCC(F)(F)C4C3)n2)cn1 +COCC(C)(C)OC(=O)N1CCC2(CC1)CC2CNC(=O)N1Cc2ccncc2C1 +Cc1ccc(CN2CCC(C(=O)Nc3ccc(-c4cc5ccccc5[nH]4)cc3)CC2)o1 +Cc1ccc(C(N)=O)cc1Nc1cc(=O)n(C)c2c1cnn2-c1cc(F)ccc1F +CC(C)CC(NC(c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1)C(F)(F)F)C(=O)NC(C#N)c1ccccc1 +CC12CCC(=O)C=C1NCC1C2CCC2(C)C(C(=O)NCc3ccccc3)CCC12 +O=C(O)CN1C(=O)C(NC(=O)c2cc3sc(Cl)c(Cl)c3[nH]2)Cc2ccccc21 +N#CCC(=O)Nc1ccc(Cl)c(-c2nc3cc(C(F)(F)F)ccc3s2)c1 +Nc1nc(N)c2nc(CNc3ccc(C(=O)NC(CCCCP(=O)(O)O)C(=O)O)cc3)cnc2n1 +N#CCNC(=O)C(Cc1cccc(-c2cccnn2)c1)NC(=O)c1ccccc1 +COc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1 +Cc1cc(Nc2nccc(-c3nccs3)n2)cc(C(F)(F)F)c1 +N#Cc1ccc2cc(CN3CCN(c4ccccc4Cl)CC3)[nH]c2c1 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+C[N+](C)(Cc1ccc(NC(=O)C=Cc2ccc(-c3ccc(C(F)(F)F)cc3)cc2)cc1)C1CCOCC1 +O=S(=O)(NCc1ccco1)c1ccc(Nc2ccc(F)cc2F)cc1C(F)(F)F +CN(C)C1CC=C(c2c[nH]c3ccc(Br)cc23)CC1 +Cc1cc(C)c(S(=O)(=O)NC(C)CNc2cccc3c2cnn3-c2ccc(F)c(C)c2)c(C)c1 +CCCCOc1cc(Cc2cnc(N)nc2N)ccc1OCc1cc(OC)c(OC)c(OC)c1 +Clc1cccc(-c2nccnc2Oc2ccc(Nc3ccccn3)cc2)c1 +C=C(C)COC1CN(C(=O)C=Cc2cnc3c(c2)CCC(=O)N3)C1 +CSC(=S)N1CC2(CCCCC2)COC1=Nc1ccc(F)c2ccccc12 +C#CCN(Cc1ccc2nc(C)nc(O)c2c1)c1ccc([S+]([O-])c2ccccc2)c(F)c1 +CCNC(=O)c1ccc(C(=C2CC3CCC(C2)N3Cc2ccoc2)c2c(C)cccc2C)cc1 +Cc1c(OCCN2CCN(C)CC2)cn2ncnc(Oc3ccc(NC(=O)c4cc(Cl)ccc4F)cc3F)c12 +COc1ccc(N2CCN(c3nc(Nc4cc(C(C)(C)C)ccc4C)cc(C(=O)NCC4CCCO4)n3)CC2(C)C)cc1 +Oc1nc2cc3cc(OCCCc4nnnn4C4CCN(CC5CCCCCC5)CC4)ccc3[nH]c-2n1 +Cn1cnc(S(=O)(=O)N(Cc2ccc(F)c(F)c2)c2cc3ccccc3s2)c1 +COc1ccc(-c2csc(Nc3ccc(CCN4CCC(O)CC4CO)cc3)n2)cc1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(C(N)=O)c1ccc(F)cc1 +CC1=NC(=S)N(C(=O)OC2CCN(Cc3ccc(F)cc3)CC2)C(c2ccccc2C(F)(F)F)C1=C(O)OC(C)C +c1cncc(CNc2ncccc2-c2nnc(Nc3ccc4c(c3)OCCO4)o2)c1 +O=C(c1ccc(Br)c2ccccc12)c1cn(CCN2CCOCC2)c2ccccc12 +O=C(NC1CCC(Nc2cc(-c3cccc(NCC4CCCNC4)n3)c(Cl)cn2)CC1)OCc1ccccc1 +Cc1cccc(CNC(=O)c2cc(-c3ccco3)nc(N)n2)c1 +O=C(Nc1ccc(-c2ccc3ccccc3c2)cc1)Nc1ccc2c(c1)NC(=O)C2=Cc1ccc[nH]1 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)N(c3ccccc3)c3ccccc3)CCC12 +COc1cccc2occ(Cc3coc4ccccc4c3=O)c(=O)c12 +CC(C)c1cc(-c2ccccc2)cc(-c2ccccc2)[n+]1Cc1ccc(S(N)(=O)=O)cc1 +Ic1ccc(CNc2ccc3c(c2)C24CCCCC2C(C3)N(CC2CC2)CC4)cc1 +Cc1cn2c(N3CCN(C(=O)CCS(=O)(=O)c4ccc5cc(Cl)ccc5c4)CC3)cccc2n1 +CCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2C)OCO3)cc1 +NCCC1CCN(C(=O)C(O)(c2ccccc2)C2CCCC2)CC1 +CCCCC1CN(C2CCOCC2)C(=O)N1C1CCN(C2(C)CCN(C(=O)c3c(C)ncnc3C)CC2)CC1 +NC(C(=O)Nc1cc2cc[nH]c(=O)c2cc1Cl)c1ccccc1 +CC(NC(CCc1ccccc1)C(=O)O)C(=O)N1CC(OC(=O)NC(CS)Cc2ccccc2)CC1C(=O)O +Cc1cccc2[nH]c(C(=O)c3cc4cc(OCCN5CCCCC5)ccc4[nH]3)cc12 +OCC1OC(n2cnc3c(Nc4ccccc4F)ncnc32)C(O)C1O +CN(C(=O)c1nn(C)cc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1)C1CCCCC1 +CN(C)c1cccc2c(S(=O)(=O)Oc3cccc4c3C(=O)C=C(N3CC3)C4=O)cccc12 +CC(COc1cc2oc3c(c2cc1Cl)C(=O)c1cccnc1C3=O)N(C)C +COc1cc(C2C=C(c3ccccc3)Nc3ncnn32)cc(OC)c1OC +CC(Nc1ncnc2[nH]c(-c3ccc(CN4CCC(NCCCCCCCC(=O)NO)CC4)cc3)cc12)c1ccccc1 +NS(=O)(=O)c1ccc(N=Cc2ccc(C=Nc3ccc(S(N)(=O)=O)cc3)cc2)cc1 +CC(C)c1cc2oc(N3CCC(C(=O)NC4CCCC(CO)C4)CC3)nc2cc1Cl +N#CCN1CN(C2CCCCC2)c2c(cnc3[nH]ccc23)C1=O +Cn1nc(-c2cccc(N3CCCC(N)C3)n2)c2cc(-c3cccnc3)ncc21 +COC(=O)CNCC(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3CCCS3)c(=O)c2=O)c1O +O=C(OCN1C(=O)C2=C(C3CCC2C3)S1(=O)=O)c1c(Cl)cccc1Cl +COc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCN(S(=O)(=O)c4ccc(C)cc4)CC3)s2)cc1 +CNC(=O)c1cccc(NC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)c1 +CC(C)(Cc1csc2ccccc12)NCC(O)COc1ccccc1C#N +CN1CCC(c2ccc(Nc3nc4c(NCc5ccccc5N(C)S(C)(=O)=O)cccn4n3)cc2)CC1 +Cc1ccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2)cc1C +Nc1nc(NN=Cc2ccccc2F)nc2c1ncn2C1OC(CO)C(O)C1O +CN1C(=CC=Cc2sc3ccc(Cl)cc3[n+]2C)Sc2ccc(Cl)cc21 +O=c1[nH]n(CCCCN2CCN(c3nsc4ccccc34)CC2)c(=O)c2ccccc12 +CCC1=C(C(=O)OCC2CCCCC2)C(c2ccc(O)c(Cl)c2)NC(=O)N1 +CC=CC1(O)CC2CCc3cc(O)ccc3C2(CC)CC1(C)O +NC(=O)c1cnn2cc(-c3ccc(F)cc3)cc2c1NC12CC3CC(O)(CC(O)(C3)C1)C2 +COc1cccc(CNC(=O)c2cc(-c3nnn(CC4CCCCC4)n3)cc(C)n2)c1 +COc1cccc(C2=CCC(N3CCN(c4cccc5ccccc45)CC3)CC2)c1 +Fc1cccc(CCCNC2C3C4CC5C6C4CC3C6C52)c1 +Cc1cc(-c2cnn3c(NCCN4CCOCC4)nc(Oc4cccc(F)c4F)nc23)ccc1C(=O)NC1CC1 +O=C(C=Cc1ccc(F)cc1)NCCCCNc1ccnc2cc(Cl)ccc12 +CCNC(=O)c1noc(-c2cc(-c3ccccc3C)c(O)cc2O)c1-c1ccc(CN2CCCCC2)cc1 +N#Cc1c(N)nc(-c2ccccc2)nc1-c1ccc2c(c1)OCO2 +CC(CO)NC(=O)CCCC=CCC=CCC=CCC=CCCCCc1cccc(C(F)(F)F)c1 +COc1cccc(Cn2c(C(=O)NC3CCN(C(C)C)CC3)c(C#N)c3cccc(C)c32)c1 +COc1cc2c(c3c1C(=O)C(=Cc1ccc(O)c(O)c1)O3)CC(C(C)(C)O)O2 +CC(C)(C)n1ncc(OCc2ccc(CCCCF)cc2)c(Cl)c1=O +COc1cccc(-c2cnc3c(N)nc4ccccc4n23)c1 +CCN1CC2CN(C(=O)CC(N)Cc3cc(F)c(F)cc3F)CCN2C1=O +C=CCN1CC2C(c3ccccc3)=CCC1CN2Cc1ccc(C(=O)N(CC)CC)cc1 +CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1ccc(Cl)cc1 +COc1cc(CNC(=S)NCC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)cc(Cl)c1O +CC(C)CC1C(=O)NC(C(=O)NCC(=O)N(C)C)CCCCN(C)C(=O)OCCCC1C(=O)NO +CC(C)(N)C(=O)N1CCn2c(nc(-c3ccc(F)cc3)c2Nc2ccc(F)c(F)c2)C1(C)C +Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3ccn(C)c3c2)n1 +CC(C)c1sc(C(C)C)c(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +CC(N)CNc1nc(-c2ccncc2)nc2sc3c(c12)CCCCC3 +CCn1nc(C)cc1C(=O)Nc1cccc(Oc2ccc3c(C=Cc4c[nH]cn4)n[nH]c3c2)c1 +CC(C)C(NC(=O)c1cccc(C(=O)O)c1)C(=O)N1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1 +CCC(=O)NCCCc1cc(OC)ccc1OCc1cccc(OC)c1 +COc1ccccc1C(C)C(=O)Nc1nnc(CCSCCc2nnc(NC(=O)C(C)c3ccccc3OC)s2)s1 +Nc1c(-c2ccc(F)cc2)c(-c2ccncc2)nn1-c1ccccc1 +COC1CN(c2ncnn3c(C)nc(-c4cnn(C)c4-c4ccc(Cl)cc4)c23)C1 +O=C(OCC#CCSc1nnc(-c2cccc3ccccc23)o1)c1ccc(C(F)(F)F)cc1 +COC(=O)c1c(CNC(=O)C2CCN(S(C)(=O)=O)CC2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +Nc1cc(C(=O)N2CCCC2)cc2nc(-c3ccc(Br)o3)nn12 +COc1cc2c(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)ncnc2cc1OCCCn1nccn1 +CN1CCc2nc(NC(=O)c3cccc(C4CCCN4C(=O)c4nnn(-c5nonc5N)c4-c4ccccc4)c3)sc2C1 +CC1(c2nnc3ccc(-c4ocnc4-c4ccc(F)cc4)cn23)CCC1 +NS(=O)(=O)CCNC(=O)C(c1nc2cc(F)c(-c3ccccc3)cc2s1)S(=O)(=O)CCN1CCOCC1 +Cc1c(F)c(Oc2cccc(C(=N)N)c2)nc(Oc2ccc(Cl)c(N(C)C)c2)c1F +c1ncc(CN2CCCNCCNCCCNCC2)cc1CN1CCCNCCNCCCNCC1 +Cc1nc(NC(C)c2cccc(-c3cnc(N4CCOCC4)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +O=C(NCc1ccc(Cl)cc1Cl)C1CCN(S(=O)(=O)c2ccccc2Br)CC1 +O=S(=O)(Nc1c(O)nc2ccc(C(F)(F)F)cc2c1Cc1cc(Cl)ccc1O)C(F)(F)F +COc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNCC21 +O=C(NCC1CCC2(CCNCC2)CO1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CCCc1cc(=O)n(C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1c(-c2ccn[nH]2)cn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1C +N#CC1(c2ccccc2)CCN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)CC1 +CCn1c(=Cc2cccc[n+]2CCO)sc(=C2Sc3ccccc3N2C)c1=O +COc1cc2c(CN(C)C)c(C)c(=O)oc2c(C=O)c1O +COc1cccc(Nc2nc3cccc(-c4cccc(S(C)(=O)=O)c4)n3n2)c1 +O=C(O)c1ccccc1NS(=O)(=O)c1cccc(-c2cnn(Cc3ccccc3)c2)c1 +CN(Cc1nc2ccccc2[nH]1)C(=O)c1ccc2c(c1)CN(Cc1ccccc1)C(=O)C(CC(=O)O)N2 +O=P(O)(O)C(CCCc1ccc(-c2ccccc2)cc1)P(=O)(O)CO +CN(C)C(=O)n1nnc(Cc2ccc(-c3ccccc3)cc2)n1 +O=C(CCCCc1ccc(O)cc1)NN=Cc1ccc(O)c(O)c1O +Nc1ncc(-c2ccc(-c3ccccc3Sc3cnccn3)cc2F)cn1 +N#Cc1ncc2nc1OCC=CCOc1cc(OC(=O)N3CCC(N4CCCCC4)CC3)c(Cl)cc1NC(=O)N2 +CCc1cc2c(cc1OC)Nc1cc(-c3ccc([N+](=O)[O-])c(OC)c3)ccc1C(=O)N2 +CCS(=O)(=O)Nc1ccc(Oc2ccc(Cl)cc2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1 +CC1(C)Oc2cc(C(=O)c3coc4ccccc34)cc(O)c2C2CC(O)CCC21 +CCCN(c1c(OC)nn2c(-c3c(OC)cc(COC)cc3OC)csc12)C1CCCOCC1 +CC(=O)n1c2ccccc2c2cc(CN3CCC4(C=Cc5ccccc54)CC3)ccc21 +CN1C(=O)Nc2ccc([N+](=O)[O-])cc2C12NC(=O)NC2=O +CCN(C(=O)CO)C1CN(C(=NC#N)Nc2cccc(OC)c2)N=C1c1ccc(Cl)c(Cl)c1 +Cc1ccc(OCC(=O)NC(=S)Nc2ccccn2)c(Br)c1 +COC(=O)CC1N=C(c2ccc(Nc3ccccc3)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(F)c(CN4CCN(C)CC4)c3)nc2n1 +CCCCS(=O)(=O)NCc1ccc(CC(=O)N(C)C(CN2CCC(O)C2)c2ccccc2)cc1 +CCOC(=O)c1c[nH]c2ncnc(-c3ccc(N4CCS(=O)(=O)CC4)cc3)c12 +COCCN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +O=C1OC2(CCC(CNc3ccc(-c4ncccn4)cn3)CC2)CN1c1ccccn1 +Cn1cc(-c2cc(S(=O)(=O)C(F)(F)F)ccc2NCC2CC2)c2cc[nH]c2c1=O +CCCCn1ccc(-c2ccc(Oc3ccnc(C)c3)c(Cl)c2)c(C#N)c1=O +Cc1nc(N)nc2c1cc(-c1cn[nH]c1)c(=O)n2C1CCC(C)(O)CC1 +COc1ccc2c(c1NC(=O)C(C)(C)CCCc1ccc(CC(C)C)cc1)OCCC2=O +CC(C)C(C)NC(=O)c1cc(-c2cc3ccccc3n2C)cc(C(=O)NCCc2ccccn2)n1 +Nc1nc(-c2ccc(Oc3ccc(F)cc3)cc2)c2ccccc2n1 +O=C1CCCC(c2cccc3c2OCCO3)N1Cc1cccc(-c2ccccc2)c1 +CCC(CC)(NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1)C(=O)OC +CNc1cc(NS(C)(=O)=O)ccc1Nc1c2cccc(C)c2nc2c(C)cccc12 +CCCCC1(CC(=O)O)OCCc2c1[nH]c1c(Cl)ccc(Cl)c21 +O=C1c2ccoc2CCC1CCN1CCC(c2noc3cc(F)ccc23)CC1 +N#Cc1cc2ccc(N3CCNCC3)cc2n2c1nc1ccccc12 +O=C(Nc1ccc(CCN2CCc3ccccc3C2)cc1)c1cnc2ccccc2c1 +CC(N)CNc1cc2nc[nH]c(=O)c2c(Nc2cccc3cc[nH]c23)n1 +O=C(c1ccc(O)cc1)c1oc2cc(O)ccc2c1-c1cccc2ccccc12 +Cc1nc(-c2nc3c(s2)CN(C(=O)CCc2cccnc2)CC3)cs1 +CN(c1ccc(S(=O)(=O)NC(C)(C)C)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +O=C(c1ccc(F)c(O)c1)c1cccc(-c2ccccc2)n1 +CC(C)CC(NC(=O)c1cccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)c1)C(N)=O +COc1cc(Nc2cccn(C(C)c3ccc(F)cc3)c2=O)ccc1-n1cnc(C)c1 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+O=C(CN1CCN(Cc2ccc(Cl)cc2)CC1)N1c2ccccc2C2CCCCC21 +Cc1ccn(-c2ccc(C(=O)N3CCC(F)(F)C(=CC(=O)NCc4cnccn4)c4ccccc43)c(Cl)c2)n1 +O=C(CC(NC(=O)c1ccccc1)c1cccc(F)c1)NC(Cc1ccc(F)cc1)B(O)O +NC(CO)(CCc1ccc(-c2coc(-c3cccs3)n2)cc1)COP(=O)(O)O +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1ccnc(COc2nn3c(-c4ccccc4)nnc3c3c2C2CCC3CC2)c1C +CCc1nc2cc3c(cc2o1)CCN(CCCSc1nnc(-c2ccc(F)c(F)c2)n1C)CC3 +COC(COc1cccc2ccccc12)CN1CCC(Cc2ccccc2)CC1 +O=C(Cc1ccc(F)cc1)NC(=O)Nc1ccc(Oc2ccnc3[nH]cc(-c4cccnc4)c23)c(F)c1 +Cn1c(CNc2ccc(C(=N)N)cc2F)nc2cc(C(=O)N(CCC(=O)O)c3cc(F)cc(F)c3)ccc21 +CCNC(=O)c1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)cc1 +CNC(=O)c1cc(Oc2ccc3nc(Nc4cccc(OC(F)(F)F)c4)ncc3c2)ccn1 +Nc1nc(N)c(F)c(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)o2)c1F +COc1ccc(Nc2ccc(CCNCC(O)c3ccc(O)c4[nH]c(=O)ccc34)cc2)cc1-c1ccccc1 +Cc1sc2[nH]c(=S)n(CCCn3cncc3C)c(=O)c2c1-c1ccccc1 +CN(CCC1CN=C(c2ccccc2)c2ccccc2N1C)C(=O)c1cccs1 +O=C(C=Cc1ccccc1Sc1ccc(Cl)cc1Cl)NCCCn1ccnc1 +COC(=O)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 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+[O-][n+]1nc2c(-n3cccc3)cnn2c2cc(Cl)ccc21 +CCCSc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1cccnc1)CC2 +Oc1ccc2c(c1)C13CCN(CC(F)F)C(C2)C1(O)Cc1cc2ccccc2nc1C3 +CCCCCCNC(=O)CCCn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1 +COCCn1cc(-c2cnc(N)c(C(=O)Nc3ccnc(C)c3)c2)cn1 +CCC1(CC)CC(NC(=O)Nc2ccc3c(c2)NC(=O)CO3)c2cccc(F)c2O1 +CCOn1c(Sc2cc(C)cc(C)c2)c(CC)c(=O)[nH]c1=O +CCOc1ccc2c(NNS(=O)(=O)c3ccccn3)cc(C)nc2c1 +COc1cc2c(Nc3ccc(NC(=O)Nc4ccccc4)cc3)ncnc2cc1OCCCN1CCN(C)CC1 +CC(NC(=O)C1COCCN1)c1ccc(CN2Cc3ccc(OCC4CC4)cc3C(F)C2)cc1 +Cc1ccc(S(=O)(=O)N2CC(=O)NCC2CC(=O)NC2CCCc3cc(CN4CCCCC4)ccc32)cc1 +CCCNC1CCc2c(cccc2CS(=O)(=O)C(F)(F)F)C1 +O=C(C#Cc1ccc2c(c1)OCO2)N1CC2CNCC(C2)C1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1NC(=O)c1cccc(-c2cnn(C)c2)c1 +CCOC1CN(C)CC1NC(=O)Nc1cc2[nH]nc(OC)c2c(CO)n1 +Cc1cc(=O)oc2c(C)c(OC3CCCC3=O)ccc12 +c1ccc2c(c1)CC(Nc1nc(-c3ccsc3)nc3ccccc13)C2 +CN(C)CCNc1cnn(C2CC(C)(C)CC(C)(C)C2)c(=O)c1Br +COc1ncnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12 +Cn1nnnc1-c1ccccc1CNC(=O)Cn1c(Cl)cnc(NCC(F)(F)c2ccccn2)c1=O 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+NCCCC(NC(=O)c1ccc(N(C=O)Cc2cnc3nc(N)nc(N)c3n2)cc1)C(=O)O +Cc1ccc(-n2cc(-c3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)nn2)cc1Nc1nccc(-c2cccnc2)n1 +O=c1n(Cc2nc3ccccc3[nH]2)c2ccccc2n1Cc1ccccc1S(=O)(=O)O +CCOC(=O)c1oc2cnccc2c1Nc1cnc2ccccc2c1 +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccc(C)cc3)nc12 +CCN(CC)C(=O)c1cc2c(OCCC3CCCCN3)c(-c3cc(C)cc(C)c3)c(O)nc2cc1Cl +O=C(O)c1cccc(Nc2cccc(C(F)(F)F)c2)c1 +CCCCCCCCC(SCCCCCC)C(=O)Nc1c(SC)cc[n+](C)c1SC +COc1c(C(=O)NC2CCN(C3CCCCCC3)CC2)cc(Br)c2ccccc12 +CC(C)c1cn2ccccc2c1S(=O)(=O)c1ccc(OCCCNCc2ccccc2)cc1 +Fc1ccc(-c2ccc(-c3cnc4c(-c5nnn[nH]5)cnn4c3C3CCCCC3)cc2)cc1F +O=C(Nc1ccc(-n2cnnn2)cc1)C1CCN(Cc2cc3ccccc3o2)CC1 +Clc1ccc(CN=c2ccn(Cc3ccccc3Cl)c3cc(Cl)ccc23)c(Cl)c1 +COCC1CN(C(=O)c2ccc3cc(Oc4ccc(C(F)(F)F)nc4)ccc3n2)CCN1 +O=C(O)C1CCCC2c3ccccc3CC(CS)C(=O)N12 +Cc1oc2c(cc(NS(=O)(=O)c3ccc4c5c(cccc35)C(=O)N4)c3ccccc32)c1C(=O)OC(C)C +N#CC(=C(c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1 +CN(C)CC(C)(C)Cn1c(C2CCCCC2)nc2cc(C=CC(=O)NO)ccc21 +CCCCCCC(Sc1nc(Cl)cc(Nc2nc(-c3ccccc3)cs2)n1)C(=O)O +CC(=O)N1CC(c2[nH]c(-c3ccccc3)nc2-c2ccccn2)CCC1c1ccccc1 +COc1cc(C2CCNCC2)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +CC(=O)N1CCc2c(c(-c3cccc(C#N)c3)nn2C2c3cc(Cl)cc(F)c3CC2O)C1 +Cc1ccc2[nH]c(C(=O)N3CCN(C)CC3)cc2c1 +CC(C)(O)CNc1ncc(C(=O)NC2C3CC4CC2CC(O)(C4)C3)c(C2CCC2)n1 +CC(C)(CNC(=O)C1(O)CCCCC1)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +CN(C(=O)c1nccs1)C1CCCN(c2nc(Cl)nc3cc(N4CCOCC4)ccc23)C1 +COc1ccc(CCCCCCCCOc2ccc(CSCc3ccc(C(=O)O)cc3)nc2C=CC(=O)O)cc1 +Nc1ccc(CN2CCC(NC(=O)C(O)(c3ccccc3)C3CCC(F)(F)C3)CC2)cc1F +CC(C)C(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CC(=O)N1CCOCC1)CC1CCCCC1 +COc1cc(Nc2nc(C)cc(Nc3ccc(Cl)cc3)n2)ccc1-n1cnc(C)c1 +NCCCNc1ccccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +Cn1nc2c(c1Cc1ccccc1Cl)-c1nc(Nc3ccn(Cc4ccncc4)n3)ncc1CC2 +NC1CN(c2ccccn2)CCC1c1cc(F)c(F)cc1F +COc1ccc2nc(-n3c(O)nc4c3CCCC4)oc2c1 +CC(C)Cn1c(C(F)(F)F)nc2c1CN(C(=O)CC(N)Cc1cc(F)ccc1F)CC2 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(NC(=O)c3csnn3)cc2)cc1)C(=O)O +CCSc1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CN(C)c1ccc(C=Cc2sc3ccc(F)cc3[n+]2Cc2ccccc2)cc1 +CONC(=O)c1cn(C)c(=O)c(F)c1Nc1ccc(Br)cc1F +COCc1nc2c(C(=O)NCc3cccs3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +COCn1ccc2cc(C3=NCC(c4cc(OC)c(OC)c(OC)c4)O3)ccc21 +CCn1c(=Cc2scc[n+]2CC)sc(=C2SC3=C(CCCC3)N2C)c1=O +O=c1[nH]c(OCCCOc2ccc(Cl)cc2)nc2ncccc12 +Cc1cc(C)c(S(=O)(=O)NC(Cn2ccc3ncccc32)C(F)(F)F)c(C)c1 +Nc1nc2[nH]cc(Cc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc3)c2c(=O)[nH]1 +CN1CCN(C2Cc3ccccc3Sc3ccc(-c4ccnn4C)cc32)CC1 +COc1cc(C)c2nc3[nH]nc(C)c3c(C(=O)c3ccncc3)c2c1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)CCCN(CCO)C2 +O=C(O)CC(NC(=O)CCCCCCc1ccc2c(n1)NCCC2)c1cnc2ccccc2c1 +CNc1nc2[nH]c(-c3cccc(CNC(=O)CCOC)n3)cc2c2c1ncn2C +N#CC(C#N)C(C(Sc1ccc([N+](=O)[O-])cc1)=C(O)c1ccccc1)c1cccs1 +CC(C)CCNC(=O)c1cnc(NC(=O)N2Cc3ccccc3C2)s1 +CN1CCC(c2ccc(Cl)cc2)C(c2nc(-c3ccccc3)no2)C1 +CC(C)CC(NC(=O)c1cccc(-c2ccc(Oc3ccc(F)cc3)cc2)n1)C(N)=O +Nc1n[nH]c2cccc(-c3ccc4c(C(=O)Nc5cccc(C(F)(F)F)c5)cccc4c3)c12 +CC1(c2nc(NC(=O)c3ncc(C(F)F)cc3N)ccc2F)N=C(N)OCC1(F)F 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+Cc1cc(C)n(-c2nc(NC(C)C)nc(NC(C)(C)C)n2)n1 +O=C(O)Cc1ccc(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1 +CCN(CC=CC#CC(C)(C)C)Cc1cccc(OCCNS(=O)(=O)c2cccs2)c1 +CC(NP(=O)(OCC1C=CC(n2cnc3c(N)ncnc32)C1)Oc1ccccc1)C(=O)OC(C)(C)C +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2Cc3n[nH]cc3C1c1c(F)cccc12 +COc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(N3CCCC3)c2c1 +C1=C(c2ccccc2)CCC(CCN2CCN(c3ccccn3)CC2)C1 +CCCC1CCN(C2C=C(C(=O)O)CC(N)C2NC(C)=O)CC1 +COc1ccc(CCCCN(C)CCOc2cc(F)cc3c2OCCC3=O)cc1 +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C)c3)cn2CCN(CC)CC)CC1 +C=CC(=O)NCCCCC(NC(=O)OCc1ccccc1)C(=O)NCC(=O)O +Cc1ccc(F)cc1OC1CN(C(C)c2nc3c(cnn3C3CCOCC3)c(=O)[nH]2)C1 +CCCCCCCNC(=O)Oc1ccc2c(c1)CN(C)C(c1ccsc1)N2C +CCC(N)(C#Cc1nc(-c2ccccc2Cl)c(-c2ccc(Cl)cc2)cc1C#N)CC +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)N1CC2CC1CN2 +COc1ccc2cc(S(=O)(=O)NN(Cc3cccc(C(=N)N)c3)C(=O)N3CCCCCC3)ccc2c1 +CC(=O)Nc1cccc(Nc2ncnc(N3CCC(OCc4ccc(C)cc4)CC3)n2)c1C +CCC(CC)OC1C=C(C(=O)O)CC(NC(N)=NC)C1NC(C)=O +O=C(NCCCCc1ccccc1)Nc1ccc2ncc(-c3ccc(O)c(F)c3)nc2n1 +CC(C)(C)C(=O)c1c[nH]c2ncc(Nc3ccc(C=C(C#N)c4nccs4)cc3)nc12 +O=C(OCCCC1CCc2ccccc2N1S(=O)(=O)c1ccc(Cl)cc1)N1CCC(N2CCCCC2)CC1 +CS(=O)(=O)NC(=O)CCc1ccc(-c2c(C=Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cc1 +O=C(CCCNc1ccccn1)Nc1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2)C(=O)O)cc1 +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NCc1ccc(C(=O)O)cc1 +Cc1c(-c2cccc(Cl)c2)nc(O)n1C1CCN(Cc2ccccc2)CC1 +O=c1sn(-c2cccc(C(F)(F)F)c2)c(=O)n1Cc1ccc(F)cc1 +Fc1ccc(-c2n[nH]c3cc(C(F)(F)F)cnc23)cc1F +N#Cc1c(-c2ccc(C(F)(F)F)cc2)cc(N2CCNCC2)n2c1nc1ccccc12 +COc1cc(-c2ccc3c(c2)NC(=O)C3=Cc2cc(C(=O)NCCCn3ccnc3)c(C)[se]2)ccc1O +Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)c3ccc(NC(=O)c4ccncc4)cc3n2)cn1 +N#Cc1ccc2c(c1)CC1C2CCCN1C(=O)c1ccc2[nH]cnc2c1 +CN(C)C1CCN(CC2CCC(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(Cl)c(O)c(Cl)c5)cc34)CC2)C1 +CCNc1cc(-n2nc(C(C)C)c3c(-n4cnc(-c5cnn(C)c5)c4)ccnc32)ccc1C(N)=O +Cn1c2cc(CCCCN3CCCC3)c(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +O=C(Nc1ccc(Oc2ccnc3[nH]c(=O)[nH]c23)cc1)Nc1cccc(OC(F)(F)F)c1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCC(C(=O)O)CC2)C1=O)c1ccccc1 +Cc1c(Cc2ccccc2)c(=O)on1C(=O)N1CCCCC1 +CN(C)C(=O)CN1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc21 +CCn1cncc1C(OC)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(-c3ccccc3)c1)cc(=O)n2C +COc1ccc(Cc2ccc(OC)c(OC)c2OC)cc1[N+](=O)[O-] +Cc1ccc2nc(C)c(-c3cc4nc(N5CC(O)C5)cc(NC5CCOCC5)n4n3)nc2c1 +CCc1cc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)nn1CC(C)C +CCN(CC)c1ccc(C=NNC(=O)Cn2nnc3ccccc32)c(O)c1 +Cc1cc(C)cc(Sc2c(CN3CCCCC3)c(C)[nH]c(=O)c2I)c1 +CN(C)C1CCN(c2ccc(-c3coc4cc(-c5ccc(OC(F)(F)F)cc5)ccc4c3=O)cn2)C1 +Nc1nnc(-c2ccc3[nH]cc(-c4cccc(N5CCOCC5)n4)c3c2)o1 +CC(C)(C)C#CC=CCN(c1cccc2c1CCC(=O)N2)S(C)(=O)=O +CC1c2nnn(-c3cnccn3)c2CCN1C(=O)c1ccc(Cl)cc1Cl +CCN1CCC(c2ccccc2)=C(C(=O)OCCc2ccccn2)C1 +CCCSc1nc2cc(-n3nc(C)n(C(F)F)c3=O)c(F)cc2s1 +C[N+](C)(C)CCOC(=O)C(c1ccccc1)c1ccccc1 +N#Cc1ccc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCc4ccc(F)cc4)c3)C2)cc1 +O=C(NO)C1Cc2ccccc2CN1S(=O)(=O)c1ccccc1 +CS(=O)(=O)c1ccc(C2CN3CCCC3c3ccccc32)cc1 +COc1cc(C2C3=C(COC3=O)Nc3cc4c(cc32)OCCO4)cc2c1OCO2 +Cc1c(N(CCOC(C)(C)C)S(=O)(=O)c2ccc(C(=O)O)cc2)sc2ccccc12 +CC(C)c1nc2ccccc2n1Cc1ccc2c(-c3ccc(F)cc3)cc(C(N)=O)nc2c1 +Cc1cc(C2CCN(CCO)CC2)cc2[nH]c(-c3c(NCCn4cc(Cl)cn4)cc[nH]c3=O)nc12 +Nc1nc2c(cnn2CCc2ccc(-c3ccc(OC(F)(F)F)cc3)cc2)c2nc(-c3ccco3)nn12 +O=C(Nc1ccc(Cl)cc1)c1ccc2cc3n(c2c1)CCCNC3=O +O=C1CC(c2cccc(-n3ccnc3)c2)=Nc2ccc(C#Cc3ccccc3F)cc2N1 +O=C(Cc1c(-c2ccc(Cl)cc2)nc2ccc(Cl)cn12)N1CCCCC1 +Cc1ccc(Sc2cncc3sc(C(N)=O)cc23)c(C)c1 +O=C(O)CCC(=O)NC(CC(=O)O)Cc1ccc(-c2ccccc2)cc1 +O=c1cc(-c2ccoc2)oc2cc(O)c(O)c(O)c12 +CC(C)(C(=O)Nc1nccs1)C(c1ccccc1)c1ccc(O)c(Br)c1 +Cc1cn(-c2cccc(-c3c[nH]c4ccc(-c5nnc(N)s5)cc34)n2)cn1 +CCCCCS(=O)(=O)NC(=O)CCc1ccc(OCCN2CCCC2=O)cc1Oc1ncc(C(F)(F)F)cc1Cl +CSc1nn2cc(-c3nc4ccc(OCc5ccccc5Cl)cc4o3)nc2s1 +Cc1cc(C)cc(-c2nc(C(F)(F)F)n(CCC(O)CC(O)CC(=O)O)c2-c2ccc(F)cc2)c1 +CCCCC1CN(CC2CCOCC2)C(=O)OC12CCN(C1CC3CN(C(=O)c4c(C)ncnc4C)CC3C1)CC2 +CCNC(=O)c1c(-c2ccccn2)c(-c2ccc(F)cc2)c(CCC(O)CC(O)CC(=O)O)n1C(C)C +COc1ccc(C(Cc2ccc(Cl)cc2)NCC(O)Cc2ccc(O)c(NS(C)(=O)=O)c2)cc1OC +OCC1OC(n2cnc3c(SCc4ccc(OC(F)(F)F)cc4)ncnc32)C(O)C1O +CC(=NOC(c1ccc(OCc2ccc3ccccc3n2)cc1)C1CCCCC1)C(=O)O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccccc4OC(F)(F)F)nc23)N1 +CCOc1ccc(OS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +Cc1nnc2n1-c1ccc(-c3cncc(C(C)(C)O)c3)cc1CC2 +Cc1cccc(C)c1N1CC(CN(C)C(C)C)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)C(C)C1=O +CN1C(=O)N2C(=NCC2CN2CCN(c3ccccc3Cl)CC2)c2ccccc21 +NC1CCC(CNC(=O)C2CCCN2C(=O)C(Cc2ccccc2)c2ccccc2)CC1 +O=C1c2ccccc2CCC1CN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +O=C(Nc1ccc(C(=O)N2CC3CSCCN3Cc3ccc(F)cc32)cc1)c1ccccc1-c1ccccc1 +CC(C)=CCc1cc(O)c2c(=O)c3cccc(O)c3oc2c1O +Cc1c(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nn4)CC3CO2)ccc(F)c1C#N +NC(=O)c1ccc(-c2ccc3[nH]nc(-c4cncc(OC5CNCCC56CC6)n4)c3c2)c(F)c1 +COc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3cc(Cl)ccc32)ccc1OCCN1C(=O)CN(C)C1=O +Cn1cc(-c2cc(C(N)=O)nc3cc(Cc4cc(Cl)nc(C(F)(F)F)c4)ccc23)cn1 +COc1cccc(C2=CCC(N3CCN(c4ccccc4)CC3)CC2)c1 +COc1cccc2c1CCCC2CCCNCC(=O)NC1CCCCC1 +CCC(=O)C1OC(n2cnc3c(N)nc(C#Cc4ccccc4)nc32)C(O)C1O +Cn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2-c2ccc(F)c(F)c2)CC1 +Brc1cc(Br)c2c(c1)C(NCCCNc1nc3ccc[nH]c-3n1)CCN2 +CC1(C)OCC(COc2ccc(F)cc2C2CCCN2c2ccn3ncc(C(N)=O)c3n2)O1 +CNc1nn2c(C)ccnc2c1S(=O)(=O)c1ccccc1 +Cc1cccnc1CN1CCC2(NC(=O)N(c3ccc(-c4ccccc4)cc3)C2=O)C(C(=O)O)C1 +CCCOCCn1c(=O)nc(NCCO)c2nnc(-c3ccc(OC)nc3)cc21 +O=C(Cc1ccc(F)cc1)NN=C1C(=O)Nc2ccc(C(=O)N3CCC(NC4CC4)CC3)c(Cl)c21 +CCOC(=O)C1CCCN(CCCCCCOc2ccc3oc(-c4ccccc4)cc(=O)c3c2)C1 +CCC(COC)NC(=O)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +CC(Oc1cc(-c2cc(-c3cc(CN(C)C)cs3)cnc2N)ccc1C(N)=O)c1ccccc1C(F)(F)F +NC(=O)c1ccc(N2CCC(CCc3ccccc3)C2)c2cncnc12 +O=C(c1ccccc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncccn2)c1 +C#Cc1cccc(Nc2cc(C)nc3ccc(NC(=O)Nc4ccc(N(CCCl)CCCl)cc4)cc23)c1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)C3CCC3)cs2)CO1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cnc(N)nc1 +COc1cc(O)ccc1C=CC(=O)OCCc1ccc(O)cc1 +CCOC(=O)c1ccc2[nH]c3c(OC)c4[nH]c5ccc(C(=O)OCC)cc5c4cc3c2c1 +Cc1cccc(-c2[nH]c(CNc3ccc(CC#N)cc3)nc2-c2ccc3ncnn3c2)n1 +CON(C)C(=O)C1C2CC3CCC1N3CC2=Cc1ccc(Cl)c(Cl)c1 +O=C(O)CCc1ccc(OCc2nc(-c3ccc(F)cc3)no2)cc1 +COC(=O)c1ccc(NS(=O)(=O)c2sc3ccc(C)cc3c2C)c(S(C)(=O)=O)c1 +O=C(Nc1ccc(F)c(-c2nc3cc(-c4ccccc4)cnc3[nH]2)c1)N1CCCC1 +CC(NC1CCCc2c1[nH]c1ccc(Br)cc21)c1ccccc1 +O=C(NC(Cc1nc2cc(Cl)ccc2[nH]1)C(=O)O)c1cc2ccccc2s1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1C2CCCC1CC(C(=O)O)C2 +CCCN1C2CCC1CC(=C(c1ccccc1)c1ccc(C(=O)N(CC)CC)cc1)C2 +CCC1(O)CC(=O)OCc2c1cc1n(c2=O)Cc2cc3cccc(F)c3nc2-1 +Nc1ncncc1-c1ccnc2c(-c3ccc(F)cc3Cl)csc12 +Cc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(OCc3ccccn3)cc1)CC2 +Cc1ccc(C(N)=O)cc1Nc1ncnn2cc(C(=O)c3ccccc3)c(C)c12 +CC(C)NC(=O)c1ccc(CN(C2CCCCNC2=O)S(=O)(=O)c2ccc(Cl)cc2)cc1 +Cc1nc(-n2ccc(O)cc2=O)sc1C(=O)NCc1ccncc1 +COc1ccc(C(NC(=O)c2cc(F)c3cnc(NCC4CC4)nc3c2)c2cnn(C)c2)cc1F +CCCCCCCN=c1ccn(Cc2ccccc2)c2cc(Cl)ccc12 +CNC(=O)c1c(NCC2CCC3(CCC3)CC2)nc(C#N)nc1OCCC1CCN(C)CC1 +CC1NC(=O)c2cc3ccc(C(=O)Nc4cnn(C)c4)cc3n2C1C +Fc1cccc(-[n+]2nc(-c3ccc(OCc4ccccc4)cc3)nn2-c2ccccc2)c1 +Cc1cnc2[nH]cc(C(=O)Nc3cncc(C(=O)c4cn(C(C)C)c5ncncc45)c3)c2c1 +CCOC(=O)N1CCC(N2CCC(C3(c4ccc(S(=O)(=O)c5ccc(OC)cc5)cc4)SCCCS3)CC2)CC1 +Cc1noc(C)c1CN1CCC(CCOc2ccc(-c3cc4c(ncn4C)c(C#N)n3)cc2C(F)(F)F)CC1 +O=C(Cc1ccccc1C(F)(F)F)N1CCC(c2cc(-c3ccc(F)cc3)nn2-c2ncccn2)CC1 +CC(C)NC(=O)c1sc2nc3c(c(-c4cccs4)c2c1N)CN(C)CC3 +CC(C)(CNC(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nsnc12)c1ccc(Cl)cc1 +CCCCCN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +CCNC(=O)c1nnn(-c2cc(C(C)C)c(O)cc2O)c1-c1ccc(CN2CCNCC2)cc1 +Nc1cncc(Nc2ccc(Oc3ccc(F)cc3)cc2)n1 +COc1cc2c(cc1OCCN(C)C)Cc1c-2n[nH]c1-c1ccc(-c2ccc(O)cc2)cc1 +O=C(C=Cc1ccc(-c2ccc(Cl)cc2)cc1)Nc1ccc(CN2CCCCC2)cc1 +COc1ccc2c(c1)C1(CC1c1ccc3c(C=Cc4ccc(CN5CC(C)OC(C)C5)cc4)n[nH]c3c1)C(=O)N2C +O=C(Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1)N1CCN(c2cccc(Cl)c2)CC1 +Cc1c(-c2cn(C(C)C)cn2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +O=C(CCCc1cccs1)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CCCCCCC(=NOCCCCC(=O)O)C(Cc1ccccc1)n1ccnc1 +Cc1ccccc1C(Oc1cc(OCc2ccsn2)ccc1C#N)C(=O)O +CC(C)(C)C12COC(c3ccccc3N=C=S)(OC1)OC2 +O=C(NC(Cc1ccc(OCCc2ccc3c(n2)NCCO3)cc1)C(=O)O)c1c(Cl)cccc1Cl +COC1=CC(c2ccc[nH]2)=NC1=Cc1[nH]c(Cc2ccc(F)cc2)cc1Cc1ccc(F)cc1 +O=C(Nc1n[nH]c2nnc(-c3cccc(F)c3F)cc12)C1CCCC1 +CC(O)c1nccc(N2CCN(c3cnc4cc(Cl)c(Cl)cc4n3)CC2)n1 +O=C(c1ccc(C(=O)N2CCN(c3ccc(OC4CCN(C5CCC5)CC4)cc3)C(=O)C2)cc1)N1CCC1 +O=C(C=Cc1ccc(Sc2cccc(OC3CCNCC3)c2)c(C(F)(F)F)c1C(F)(F)F)N1CCOCC1 +CCC(C1=C(CCN(C)C)Cc2cc(Cl)ccc21)c1ccccn1 +O=[N+]([O-])c1ccc(Oc2cccc(N(Cc3cccc(OC(F)(F)C(F)F)c3)CC(O)C(F)(F)F)c2)cc1 +COc1ccc(C#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(C1CCOCC1)C2=O +COc1ccc(-c2nc(NCc3ccc4c(c3)OCO4)ncc2C(=O)NCCOc2ccccc2)c(OC)n1 +NC(=O)c1cccc2c1C(=O)N(CC1CCN(Cc3ccc(F)cc3)CC1)C2 +C#CCOc1cnc(C(=O)Nc2cnc(F)c(C3(C)CC(C(F)(F)F)OC(N)=N3)c2)cn1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4ccc(-c5ccccc5)cc4)nc31)C(O)C2O 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+COC(=O)c1ccc(CCc2c(C(=O)O)[nH]c(=O)[nH]c2=O)cc1 +CC(Cc1ccc(NCc2cccc(Oc3ccccc3)c2)cc1)C(=O)O +O=C(O)c1ccc2ccc(C=Cc3cn4nc(Cl)cc(N5CCOCC5)c4n3)nc2c1 +NCCCCCCCCCCN1CCN(CC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +CCOc1ccccc1C1C(C#N)=C(N)Oc2cc(N(C)C)ccc21 +Cc1cc2nc(CN(C)Cc3ncccc3C)[nH]c2cc1C +Nc1ncnc2c1c(C(=O)c1ccc(NS(=O)(=O)c3c(F)cccc3F)cc1)cn2C1CCCC1 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C(C)(C)C)cc4)CC3)c2cc1OCCOC +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1ccccc1Cl +CC(C)(C)c1ccc(N(C(=O)CCC(=O)Nc2ccc(-c3ccc(OCC(=O)O)cc3)cc2Cl)C2CC2)c(Cl)c1 +O=C(O)c1ccc(-c2ccnc(Nc3ccccc3)n2)cc1 +CCCN(CC1CCCC1)C(=O)c1cc(Cl)cc(OCCCON=C(N)N)c1 +COc1ccc(NC(=O)c2ccnn2CCc2ccncc2)cc1OC +CN(C)N=C1SC(=Cc2ccc(O)c(Cl)c2)C(=O)N1c1ccccc1 +CC(NC(=O)C(Cc1cccc(C#N)c1)NC(=O)C(C)(C)N)c1nc2cc(Cl)c(Cl)cc2[nH]1 +O=C(NCC1(c2ccc(Cl)cc2)CCOCC1)c1cccc(Cl)c1F +CC(C)CC(CC(=O)OCC1(CO)CC(=Cc2cccc(C(=O)O)c2)C(=O)O1)CC(C)C +Cc1cc2c(cc1C(OCc1ccccc1F)c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4N3CCC(O)C3)no2)cc1C#N +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)cn4)CC3CO2)c1C +COc1cc2ccn(C3OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C3O)c(=O)c2cc1F +CCC(C)C(CN(CC(=O)NC(CCSC)C(=O)O)Cc1cccc2ccccc12)NC(=O)CCCCc1ccccc1 +CCCN(C(=O)OCc1ccccc1)C1CCN(CCC(CN(C)S(=O)(=O)c2ccccc2)c2cccc(Cl)c2)CC1 +O=C(O)c1csc(-n2nc(-c3cc(F)cc(F)c3)cc2O)n1 +CC(CF)Nc1ncc2c(n1)CN(C(=O)NC(CO)c1ccc(Cl)c(Cl)c1)CC2 +CNc1nc(NCc2ccc(NC(=O)C3CCN(Cc4ccccc4)CC3)cc2)c2ccc(C)cc2n1 +COc1ccc(S(C)(=O)=O)cc1CC(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1c(F)cccc1Cl)C(C)C +CN1CCC(c2coc3ccc(NC(=O)c4c(F)cccc4Cl)nc23)CC1 +O=C(Cc1cccs1)Nc1cccc(C(=O)C(=O)c2ccccn2)c1 +CN(CCCc1ccc(F)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CCNCC2)n1 +CCN(CC)CCOc1cccc(Nc2nnc3cc(-c4c(C)cccc4C)cc(C)c3n2)c1 +Nc1ncnc2c1ncn2C1OC2CC(CC(=O)O)(C(=O)O)OC2C1O +CC(C)C(CO)NCc1nc(-c2ccc(C(F)(F)F)cc2C(F)(F)F)ccc1F +COc1cccc(-c2ccc(C#N)c(C(F)(F)F)c2)c1 +CC(=O)N1CCN(c2nncc3cc(-c4c(C)ccc5c(NC6CC6)noc45)ccc23)C(C)C1 +COCC1CC2CSC(N)=NC2(c2cc(C#N)c(F)cc2F)CO1 +CN(CC(=O)N(C)C(CN1CCCC1)c1ccc(-c2ccccc2)cc1)c1ccc(Cl)c(Cl)c1 +Cc1nn(CC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)c(C)c1Cl +c1cc(C2=NCCN2)ccc1OCCCOc1ccc(C2=NCCN2)cc1 +Oc1ccc2c3c(sc2c1)-c1ccccc1OC3c1ccc(OCCN2CCCCC2)cc1 +CNC(=O)C(NC(=O)C(CC(C)C)C(O)C(=O)NO)C(C)(C)C +Cc1ccc(-n2nccn2)c(C(=O)N2CCOCC2Cc2cccc(-n3cccc3)c2)c1 +CC(Nc1c(F)ccc(F)c1F)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +Cc1nc(-n2cnn(Cc3ccc(F)cc3)c2=O)sc1C(=O)NCc1cn(C)cn1 +N#Cc1ccc(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)nc1 +Nc1nc(-c2ccco2)nc2sc(CN3CCC(F)(F)CC3)cc12 +CC1(C(=O)NC(Cc2ccncc2)C(=O)O)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Cc1[nH]c2ccccc2c1C=Cc1cc(N)c2ccccc2[n+]1C +C=CC(=O)Nc1cc2c(Nc3ccc(Br)c(Cl)c3)ncnc2cc1OCCNC(=O)CN(C)C +CC(=O)c1csc(CNC(=O)C2C(C(=O)NCCCN(C)C)C3C=CC2C32CC2)n1 +NC(=O)c1cccc2c1C(=O)N(C1CCN(Cc3ccsc3)CC1)C2 +CONC1CCC(NCC(O)C(Cc2cc(F)cc(F)c2)NC(C)=O)(c2cccc(C(C)(C)C)c2)CN1 +CCOC(=O)Cn1nc(-c2ccc(S(C)(=O)=O)cc2)c(-c2ccc(F)cc2)c1C(F)(F)F +COc1ccc2c(c1)CCC(O)C2=Cc1cc(OC)c(OC)c(OC)c1 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+Cc1ccc(CN2Cc3nc4ccccc4c(-c4ccccc4)c3C2=O)cc1 +CN(C(=O)Cn1c(=O)oc2cccc(-c3ccccc3)c21)c1ccccc1 +CCS(=O)(=O)NCc1noc(C(CCCC2CCCCC2)CC(=O)NO)n1 +FC(F)(F)c1cnc(Nc2cccc(Cl)c2)nc1Nc1ccc2[nH]cnc2c1 +CC(C)CC(NC(=O)c1ccco1)C(=O)NC1CCC(C)N(S(=O)(=O)c2ccccn2)CC1=O +CCN(CC)C(=O)c1ccc(C(=Nc2ccccc2Cl)N2CCN(CCc3cccs3)CC2)cc1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)Cc2ccccc2C(=O)O)c1=O)C(=O)C(F)(F)F +C[N+]1(C)C2CC(OC(=O)C(O)(c3cccs3)c3cccs3)CC1C1OC12 +O=C(c1ccc([N+](=O)[O-])cc1)c1nccc2c1[nH]c1ccccc12 +COc1ccc2c(c1)OCCCC=CCCC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +Cc1c(C#N)cccc1C1CN2CCN(C(=O)Cc3cnc(-n4cnnn4)nc3)CC2CO1 +O=C(O)c1ccccc1NS(=O)(=O)c1cccc(-c2cnn(Cc3ccc4ccccc4c3)c2)c1 +COc1cc2nc(N3CCC(OCCO)CC3)nc(N)c2cc1OC +CCCCN1CCN2c3c(cccc31)C1CN(CCCC(=O)c3ccc(F)cc3)CCC12 +CC(C)(C)c1cc(NC(=O)C2CCCN2C2CCCCC2)no1 +NC(=S)Nc1ccc2c(c1)Cc1cc(N(Cc3ccccc3)Cc3ccccc3)ccc1-2 +CCCCC1(CC)CS(=O)(=O)c2cc(CCC(=O)NC)c(OC)cc2C(c2ccccc2)N1 +CCN1c2ncc(CSc3ccccc3)cc2C(=O)N(C)c2ccc(Cl)nc21 +COc1ccc(CN(C)CCCCc2ccc(NC(=O)c3cccc4c(O)c5cccc(N)c5nc34)cc2)cc1OC +CC(C)(C)CC(O)C(=O)Nc1sc2c(c1C(N)=O)CC(C)(C)OC2(C)C +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(C2CCCCC2)sc2cc(O)ccc12 +NCCCn1c2c(c3ccccc3c1=O)C(=O)c1ccccc1-2 +Cc1ccc2c(c1)CN(C(=O)Nc1ccc(C(=O)N3CCN(c4ccccn4)CC3)cc1)C2 +COc1ccc2c(c1)c1c(n2C)CCCC1NC(=O)C1CC1 +CCc1cc(O)ccc1-c1ccc2c(C(N)=O)n[nH]c2c1 +CC(C)CC(NC(=O)c1cccc(S(=O)(=O)CC(C)C)n1)C(N)=O +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3cc(F)cc(F)c3)CC2)cc1 +CCc1cc2c(cc1NC(=O)CN1CC3CN(C)CC3C1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +COc1ccc(C2(O)CCC(NC3CCN(C(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)cn1 +CC(C)Oc1cccc2c1CCCC2Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O +CCN(CC)CCn1cc(-c2ccc(F)c(C)c2)nc1C1CCN(c2ncnc(N)c2C#N)CC1 +O=C(Nc1ccc2ncccc2c1)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +COc1ccc(-c2cc(=O)n(Cc3cccnc3)nc2-c2ccc(OC)cc2)cc1 +Nc1ccnc(N2CCC(n3c(=O)n(-c4ccccc4)c4cccnc43)CC2)c1 +COCC(CO)NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +OCCN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 +COC(=O)c1cncc(C(=O)Nc2cccc(CN3CCC(C(=O)NC(C)(C)C)CC3)c2)c1 +O=C(O)C1=Cc2cc(Cl)cc(Cl)c2OC1C(F)(F)F +CCCSc1nc(N2CCC(C(=O)O)CC2)ccc1C(=O)NC1CCCCC1 +O=C(Nc1ccc(Cl)cc1)C1CN(C(=O)c2cc(F)cc(-c3ccncc3)c2)CC(F)(F)C1 +CCn1c(=O)cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc21 +COc1ccc(-c2oc(O)nc2-c2cc(OC)c(OC)c(OC)c2)cc1O +Cc1[se]c(C=C2C(=O)Nc3cc(-c4ccc(O)cc4)ccc32)cc1C(=O)NCCN1CCCC1 +CCC(CC)n1c(CNC2CCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CN(c1cccc(Cl)c1)c1nc2cc(C(=O)O)ccc2c2cnccc12 +O=C1Nc2ccc(F)cc2C(C#CC2CC2)(C(F)(F)F)O1 +CCC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc(F)cc3)n[nH]c2C1(C)C +O=C(Nc1ccc(-c2nnc(NCCCN3CCOCC3)o2)cc1)c1ccccc1F +CCc1ncnc(N2CCCCC2)c1C#Cc1ccc(NC)nc1 +COC(=O)OCC1C2CCC(C)C1(C)CCC(C)=CCCC1(C)OC1C2=O +c1ccc(Nc2ccc(Oc3nccnc3N3CCCCC3)cc2)nc1 +CNc1ncc(C(=O)Nc2cc(C(=O)Nc3cccc(C(F)(F)F)c3)ccc2C)c(Oc2ccccc2)n1 +Cc1nc2c(C)cccc2c(Nc2ccc(N3CCCN(C)C3)cc2)c1C +CC(=O)NC(C)c1ccc(OC2CCN(c3cccc(C(F)F)n3)C2)cc1 +CS(=O)(=O)C1(c2nc(-c3cccc4[nH]ccc34)nc3c2OCC2COCCN32)CC1 +ON=Cc1ccc(-c2ccccc2)c(-c2ccccc2)c1O +CCCNC(=O)Nc1cccc(-c2ccc(CC(NS(=O)(=O)CC34CCC(CC3=O)C4(C)C)C(=O)O)cc2)c1 +CC(C)n1c(O)nc2ccc(-c3cccc(Cl)c3)cc21 +O=C(c1nc2c(N3CCNCC3)cccc2[nH]1)c1cccc2ccccc12 +CN(C)c1ccc(-c2cc3onc(-c4ccccc4)c3c(=O)n2C)cc1 +CC(C)(C)C(NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1)C(N)=O +CCCCN1CCC(C(=O)NO)(S(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CC1 +Cc1ccc2cc(Cn3cc(C(=O)NCc4c(Cl)cc(N)nc4C)nn3)ccc2n1 +CNCc1ccc(C2=NOC(c3nc(-c4ccc(S(=O)(=O)C(C)C)cc4)cnc3N)C2)cc1 +CN(C)c1ccc(C2=NN(c3ccc(S(=O)(=O)NC(=S)NC4CCCCC4)cc3)C(c3ccccc3)C2)cc1 +COc1cc(S(=O)(=O)c2ccc3sccc3c2)cc2c3c(oc12)CCNC3 +OC(CNCCCCCCN1CCC(c2ccc(F)cc2)C(COc2ccc3c(c2)OCO3)C1)COc1cccc2[nH]ccc12 +COCCN1CCN(c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)CC1C +O=C(O)c1cc(NC(=O)c2nc3ccccc3nc2Oc2ccc(OC(F)(F)F)cc2)ccn1 +CC(C)C(NC(=O)Cn1ccc2c(=O)n(CC(=O)c3ccccc3)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +COc1cc(CC2C(O)C(O)C(Cc3cc(OC)cc(OC)c3)N(CC3CC3)C(=O)N2CC2CC2)cc(OC)c1 +NCCCCC(NC(=O)c1ccc(F)c(F)c1)C(=O)c1noc(Cc2ccc(C(=O)NCCc3cccc(Cl)c3)cc2)n1 +OC1CCN(c2nc(N3C4CCC3COC4)c3c(-c4ccccc4Cl)csc3n2)C1 +CC1CC(N)CC(c2ccncc2NC(=O)c2nc(-c3cc(O)ccc3F)ccc2F)C1 +O=C(NCc1ncc(-c2ccc(Cl)c(Cl)c2)[nH]1)Nc1ncc(Sc2ccccn2)s1 +COCCN1CCc2ccc(Nc3ncc(Cl)c(NC4CCCCC4NS(C)(=O)=O)n3)cc2CC1 +Cn1c(OC2CCN(c3ccc(-c4ccncc4)cc3)CC2)nc(-c2ccncc2F)cc1=O +N#Cc1c(N)nc(OCc2ccnc(C(=O)NC3CC3)c2)c(C#N)c1-c1ccccc1 +Cc1onc(-c2ccc(F)cc2)c1COc1ccc(C(=O)NCC2CC2)cn1 +COC(=O)C(C#N)(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccccc1 +O=C(O)CC1CC(C(F)(F)F)CN1c1ccc(Oc2ccccc2OC(F)(F)F)cc1 +CC1(C)CC(CCNc2ccc(Cl)c(F)c2)(c2ccccc2)CCO1 +CNC1=C(N(Cc2ccc(Cl)c(Cl)c2)C(C)=O)C(=O)c2ccccc2C1=O +Cc1nc(C)c(CNc2nc(OCC3CC3c3ccc4ncccc4n3)ncc2C)s1 +CCOC(=O)Cc1c(N)nc(N)n(CCOCP(=O)(O)O)c1=O +CN1CCC2(CC1)CC(=O)c1cc(C=CC(=O)NO)ccc1O2 +COc1ccc(NC2=CC(=O)c3sc(C)nc3C2=O)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2ccnc(N(C)C(C)C)n2)cc1 +COCCCNc1ccc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)cn1 +CCc1cccc(NC(=O)c2cc(Cl)c(C3(C)CS(=O)(=O)C4(CCCCC4)C(=N)N3)s2)n1 +CN(C)C(=O)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21 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+Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(NC3CCC(N)CC3)c2c1=O +CCCCCCCCCCn1ccc(=O)c(Cc2c(Cl)cccc2Cl)c1C +NC(=O)c1cc(-c2ccc(OC(F)F)cc2)c2ccccc2n1 +CC1=NCC2CNC(c3ccccc3Cl)c3cc(Cl)ccc3C2=N1 +O=C1OCC2CCCC2N1c1ccc(C#Cc2cccc(F)c2)cn1 +CCc1nccc(-c2ccc(C(=O)N3CCN(C(C)(C)C)CC3)c(F)c2)c1C#Cc1ccc(NC)nc1 +CCOC(=O)c1cn2ncnc(Nc3ccc(F)c(C(=O)NOC)c3)c2c1C(C)C +COc1ccc(CCNc2cc(-c3ccc(N(C)C)cc3)nc(OC)n2)cc1 +O=S1(=O)c2ccccc2CN1c1cccc(Oc2ccccc2)c1 +CC(=NNC(=O)c1cccc(N)c1)c1cccc(Cl)c1 +O=C(COc1ccc(Cl)cc1)NNC(=S)NCCCCC1CCCCC1 +NCc1ccc(Cl)cc1CNC(=O)C1CCCN1C(=O)C1COc2ccccc21 +Fc1ccc(OC(c2cccc(F)c2)C2CCNCC2)cc1 +CC1(C)C(C(=O)c2cn(CC3CCOCC3)c3ccc(N)cc23)C1(C)C +Cn1c(Nc2c(Cl)ccc(CNC(=O)OC(C)(C)C)c2Cl)nc2cc(C(=O)NCC(F)(F)F)c(OCC(F)F)cc21 +COc1ccc(OC)c(CCNC(=S)Nc2ccc(Br)cn2)c1 +C#Cc1ccc2[nH]c3cnc(C(=O)OC(C)(C)C)cc3c2c1 +CN1CCCC(CN(C)C(=O)Cn2c(-c3ccccc3)c(C3CCCCC3)c3ccc(C(=O)O)cc32)C1 +CN(Cc1ccccc1Cl)C(=O)n1cnc(S(=O)(=O)C2CC3CCC2C3)n1 +CC(C)N1C(=O)C(NC(=O)C(Cc2ccccc2OC(F)(F)F)NC(=O)OC(C)(C)C)CCc2cc(F)ccc21 +COc1ccc2c(=O)c3c([nH]c2c1)CCC(F)(F)C3 +Cc1ccc2[nH]cc(C(=O)c3ccccc3NCc3ccc4cn[nH]c4c3)c2c1 +COc1cccc2oc(C(=O)Nc3ccc(-c4ccc(S(=O)(=O)NC(C(=O)O)C(C)C)cc4)cc3)cc12 +O=C(Nc1ncnc2[nH]cnc12)c1cccc(-c2cccc(-c3c[nH]cn3)c2)c1 +Cc1nc2ccc(I)cn2c(=O)c1CCN1CCc2oc3ccccc3c2C1 +Cc1nn(C2CCCCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)nc3)cc12 +CCN(CCCCNC(=O)COc1ccc(-c2cc(=O)c3c(OC)c(OC)c(OC)cc3o2)cc1)Cc1ccccc1OC +CCCCCCOc1ccc2c(c1OC)CN1CCc3cc(OC)c(O)cc3C1C2 +Cn1cnc(C(=O)N2CCN(C(=O)c3ccc(Nc4nc5ccccc5n5nnnc45)cc3)CC2)c1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2Cc3ccccc3CC2C(=O)O)c1 +O=C1N(c2cc(Cl)nc(Cl)c2)CCN1c1cnccc1C1CC1 +COc1ccc(-c2cc(CNc3nccc(Nc4cc(C5CC5)[nH]n4)n3)on2)cc1 +OCC1OC(n2c(Nc3ccccc3)nc3c(N4CCc5ccccc54)ncnc32)C(O)C1O +CC(C)(C)c1cc(NC(=O)Nc2ccc(F)cc2)no1 +Cc1cc(OCCCc2c(C(=O)NS(=O)(=O)CCNC(=O)c3ccc(F)cc3)[nH]c3ccccc23)cc(C)c1Cl +CC(NC1=NC(=O)C(C)(C(C)C)S1)c1ccccc1C(F)(F)F +O=C(O)c1cc2cc(O)ccc2n1Cc1ccc(Cl)c(Cl)c1 +c1ccc(C2CCc3cc(Oc4ncc(CNC5CC5)s4)ccc3O2)cc1 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+Cc1cc2ccccc2nc1-c1ccc(N(Cc2cccc3ccccc23)C(=O)c2ccc(O)cc2O)cc1 +O=C(Nc1ccc(C(=O)N2CCN(CCOCCO)CC2)cc1)N1Cc2ccccc2C1 +Cn1cc(-c2cc(C(N)=O)nc3cc(CN4CC(C(F)(F)F)OC(C)(C)C4)ccc23)cn1 +CC(CS)C(=O)NC(CSCc1ccc(I)cc1)C(=O)O +Nc1ncnc(Nc2ccc3c(cnn3Cc3cccc(F)c3)c2)c1C=NNCC(F)(F)F +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)Nc1ccccc1C(=O)NCc1ccc2c(c1)OCO2 +Cc1cscc1-c1noc2cnc(NC(C)c3ccccc3)cc12 +Cc1ccccc1N=C(N)NC12CC3CC(C)(CC(C)(C3)C1)C2 +CNC(C)C(=O)NC(C(=O)N1Cc2ccccc2C1C(=O)Nc1c(F)cccc1F)C(C)O +COc1ccc(Cl)cc1NC(=O)C1c2ccccc2C(=O)N(CC(C)C)C1c1cccs1 +CCn1c(NC(C)C)nc2c(C3CCN(c4ccccn4)CC3)csc2c1=O +NC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(OC(F)(F)F)c3F)CC3CC32)c2ccncc12 +O=C1CC(c2c[nH]c3ccccc23)C(=O)N1CCCN1CCC(c2c[nH]c3ccccc23)CC1 +CNc1nc(Nc2ccc(C(=O)N3CCC(C#N)CC3)cc2OC)ncc1Br +N#Cc1cc(-c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)ccn1 +O=C(Cc1ccc(Cl)c(Cl)c1)N1CCC(O)CC1CN1CCCC1 +COc1cc(C2NC(=O)NC(C)=C2C(=O)O)ccc1OCCOc1cc(C)nc2ccccc12 +CNC(=O)C(CC(C)C)NC(=O)c1cccc(-c2cccc(C(F)(F)F)c2)n1 +COC(=O)c1c(CNC(=O)c2ccc(Cl)nc2)c(=O)c2ccc(F)cc2n1-c1ccccc1 +CN1CCc2cc(Cl)c(O)cc2C(c2ccc(CN(Cc3ccccc3)c3ccc(F)cc3F)cc2)C1 +Cc1ccncc1CNC(=O)Nc1ccc(S(=O)(=O)c2ccccc2)cc1 +C=CC[N+]1(C)CCN(CCNC(=O)n2c(=O)n(C(C)C)c3ccccc32)CC1 +COc1ccc(-c2cn(-c3cc(C(=O)O)ccn3)cc2C#N)cc1 +Cc1cccc(CN2CCCC(C(=O)N3CCc4ccccc4C3)C2)c1 +COc1cc(-c2cc(NC(=O)Nc3ccc(OCCN4CCCC4)cc3)cc(OC)c2OC)ccc1C(C)=O +CNC1CCc2c(c3cc(OC)ccc3n2S(=O)(=O)c2cccc(C(F)(F)F)c2)C1 +Nc1ncnc2nc(-c3ccc(N4CCOCC4)nc3)cc(-c3cccc(Cl)c3Cl)c12 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)cc2c(=O)n(C)c(=O)[nH]c2c1=O)C(=O)C(F)(F)F +CC(=O)Oc1cccc(-c2nc(N3CCOCC3)c3cc4ncccc4n3n2)c1 +Cn1c(Cc2ccccc2)[n+]([O-])c2cc(C=CC(=O)NO)ccc21 +O=S(=O)(c1ccc2c(c1)CCNCC2)N1CCOCC1 +Cc1ccn(-c2ccc(-n3cccn3)cc2)c(=O)c1-c1ccc2nc(N)ncc2c1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NCc1ccc(F)cc1Cl +COCCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(OC(F)(F)F)cc2)c1 +COc1cccc(CN(Cc2cccc(OC)c2)c2ccc3nc[nH]c3c2)c1 +CC1(C)CC2(C)C(=CC1=O)CCC1C3CCC(=O)C3(C)CCC12 +COc1ccccc1N1CCN(CCn2nc(-n3cnc4ccccc43)ccc2=O)CC1 +CC(C)(C)c1ccc(S(=O)(=O)NCCCCCc2c[nH]cn2)cc1 +CNc1cc(NS(C)(=O)=O)ccc1Nc1c2ccccc2nc2cc(NC(=O)OC)ccc12 +Cc1ncnc(C)c1C(=O)N1CC2CN(CCC3(c4ccccc4)CN(C(=O)C(C)(C)CO)C3)CC2C1 +O=C(Nc1ccc(Cl)c([N+](=O)[O-])c1)c1ccc2ccccc2c1O +COc1ccccc1-n1nc(C2CCN(S(C)(=O)=O)CC2)cc1-c1ccc(Cl)cc1 +CCN1CCN(c2nc(C)nc3c2nc(-c2ccccc2Cl)n3CCCOC)CC1 +CNCCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc([N+](=O)[O-])c1 +OCC1CC(O)CN1CCCc1ccc(Nc2nc(-c3cccc(C(F)(F)F)c3)cs2)cc1 +Cc1nc(-c2ccccc2)c(C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)o1 +CCc1cc2c(cc1-c1cnn(C)c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CN(C(=O)Cc1cccc2occc12)C1CCCCC1N1CCCC1 +COc1ccc(Nc2ncc(N3CCC(CO)C3)cc2-c2nc(C)nc3[nH]cnc23)cn1 +Cc1c(-c2c(F)cc(C(N)=O)c3[nH]c4cc(CCO)ccc4c23)cccc1-n1c(=O)cc2c(F)cccn2c1=O +COC1CCC(C(=O)N2CC=C(c3ccc(NC(=O)N4Cc5ccncc5C4)cc3)CC2)CC1 +CC(=O)NCCCOc1ccc(-c2cc(C)cc(Nc3nccc(C(F)(F)F)n3)c2)cc1C(=O)O +Cc1ccc(Oc2ccc(-c3nc4cc(C(N)=O)ccc4[nH]3)cc2)c(Cl)c1 +COC(=O)C1CCC(CN2CCCC2)N(C(=O)Cc2ccc(Cl)c(Cl)c2)C1 +CC(=O)c1cc(NC(=O)NCCCC2CC(Cc3ccc(F)cc3)CCN2)cc(C(C)=O)c1 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+CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(C)=O)cc4)cc3)[nH]c2n(CCC)c1=O +Nc1ccccc1NC(=O)c1ccc(-c2ncc(CN3CCC3)cc2Cl)cc1 +Cc1cc(-c2cnn3c2C(=O)N(c2ccc(C(F)(F)F)cc2)CC3C)ccn1 +O=S(=O)(Nc1ncns1)c1ccc2c(c1)OCCN2c1cccc(OC(F)(F)F)c1 +CCC(C)N(CC(O)c1ccc(Cl)c(Cl)c1)C(=O)Nc1ccc(CNC(=O)C(C)(C)C)cc1 +CSc1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 +Cc1ccccc1Nc1nc(N)nc(COC(=O)c2ccc([N+](=O)[O-])o2)n1 +CN(C1CCN(CCOc2ccccc2-c2ccccc2)CC1)S(=O)(=O)c1ccccc1 +COc1ccc2cc1Oc1ccc(cc1)CC1NCCc3cc(OC)c4c(c31)Oc1cc3c(cc1O4)CCN(C)C3C2 +COCCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2noc(C)n2)cc1 +O=C(N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1)n1cncn1 +CCCCN(C)S(=O)(=O)c1ccc(C(=O)N(CCN(C)C)c2nc3ccc(C)cc3s2)cc1 +COCc1cccc(-c2cc(CCNC(C)=O)c3cc(OC)ccc3c2)c1 +Cc1c(C(=O)O)c(-c2ccc([N+](=O)[O-])cc2)c(C)n1Cc1ccccc1 +N#Cc1cccc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3F)C2)c1 +Cc1nc(N)nc(-c2c(Nc3cc[nH]n3)nc3ccc(-c4ccccc4C)cn23)n1 +CC(Cc1ccc2c(c1)OC(C(=O)O)(C(=O)O)O2)NCC(O)c1cccc(Cl)c1 +NS(=O)(=O)c1ccc(NS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)c(Cl)c1 +O=C(CC(Nc1cccc2ccccc12)C(=O)N1CCC(N2CCCCC2)CC1)N1CCC(N2Cc3ccccc3NC2=O)CC1 +Oc1ccc2c(-c3ccccc3)c3cc4ccccc4cc3nc2c1 +S=C(N1CCCc2ccccc21)N1N=C(c2ccccc2)CC1c1ccccc1 +O=c1ccc2nc(-c3ccccc3)nn(-c3ccccc3)c-2c1 +CN(C)C(=O)c1ccc(-c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)cc1 +CC=CC(=O)N1CC2(CC(n3nc(-c4ccc(Oc5ccccc5)cn4)c4c(N)ncnc43)C2)C1 +O=C(CC12CC3CC(CC(C3)C1)C2)NC1CCCC(OCCCN2CCOCC2)C1 +O=C(c1ccc(-c2ccccc2)c(F)c1)C1CCCN(CCO)C1 +CC(Nc1ncnc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +Cc1cc(-c2cnc(C(C)Nc3nccc(N4C(=O)OCC4C(C)F)n3)nc2)ccc1F +CCCCCC=CCC=CCOc1cccc(C(SCCC(=O)O)SCCC(=O)O)c1 +CCC(O)C(CC)Nc1nc(NCc2ccccn2)c2ncn(C(C)C)c2n1 +CCOC(=O)N1CCN([N+]([O-])=NOc2ccc([N+](=O)[O-])cc2[N+](=O)[O-])CC1 +CN(CCCN(C)Cc1ccc(Cl)c(Cl)c1)CCN1CCCC1 +CN1CCN(c2ccc(-c3cc4ncn(C)c(=O)c4c(N4CC(O)C(CO)C4)n3)cc2)CC1 +COCCN(C)c1ncc2ncnc(Nc3cc(C(=O)Nc4ccc(OC)c(C(F)(F)F)c4)ccc3OC)c2n1 +CCC(=O)NC1Cc2c(OC)cccc2C(c2ccccc2)C1 +O=S(=O)(NCCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1)c1ccc2ccccc2c1 +O=C(O)C(Cc1ccc(F)c(F)c1)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +COc1cc2c3c(c4ccc(NS(=O)(=O)C(C)C)cc4c2cc1OC)CN1CCCCC1C3 +CN1C(=O)C(c2ccc(OC(F)F)cc2)(c2cccc(C=CCCCO)c2)N=C1N +Cc1ccc2[nH]nc(C)c2c1-c1nc2c(c(N3CCC(N(C)C)C3)n1)CN(c1c(Cl)c(C3CC3)nn1C)CC2 +Oc1ccc2c3c1OC1c4nc5ccccc5cc4CC4(O)C(C2)N(CC(F)(F)F)CCC314 +CCN(Cc1cccc(OCc2noc(-c3ccccc3F)n2)c1)C1CCN(C2CC(C)C(C)C2)C1 +O=C(NC1CNC1)c1cc(NC(=O)c2cc(-c3ccc(F)cn3)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=c1[nH]c(C2CNC2)nc2c1oc1ccc(Br)cc12 +Clc1ccc(-c2ccc(C3=NOC(c4cccc(-c5cncnc5)c4)N3c3ccc(N4CCNCC4)cc3)o2)cc1 +[H]C([H])([H])N1CCN(C(c2ccccc2)c2ccc(Cl)cc2)CC1 +CCn1c(=O)c2nc(-c3ccc(OCOC(=O)C(C)C)cc3)[nH]c2n(CC)c1=O +CCC1(CC#N)CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +Cn1cc(S(=O)(=O)Nc2ccc(F)c(Nc3ncccc3-c3ncnc4[nH]cnc34)c2F)cn1 +CCN(CC)c1ccc2c(C(F)(F)F)cc(=O)[nH]c2c1 +COc1cc2c(cc1O)CC1c3c(ccc(O)c3O2)CCN1C +CN(C)CCN(C)c1cccc(-c2cc(-c3ccc(F)cc3O)nc(NC(=O)c3ccco3)c2C#N)c1 +C=CC(=O)Nc1cccc(-c2cn3nc(-c4ccc(Oc5ccccc5)cc4)c(C(N)=O)c3[nH]2)c1 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+CCc1nc2ccn(CC(=O)N3CCCCC3)c(=O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(C(=O)C(CCC2CCN(Cc3ccccc3)CC2)C(C)=O)cc1 +CCc1ccc(OCCNC(C)Cc2cc3c(c(C(N)=O)c2)N(CCCO)CC3)c(OC)c1 +Nc1nc(NCCNc2ncc(-c3ncc[nH]3)c(-c3cc(F)c(F)cc3F)n2)ccc1[N+](=O)[O-] +COc1cccc(NC(=O)c2ccc(NC(C)C)c([N+](=O)[O-])c2)c1 +CC(=O)NC(CCCCN)C(=O)N1CCCC(C(=O)NCCC(=O)O)C1 +c1ccc(-n2ccc(-c3nnc4n3CCCCC4)c2)cc1 +CCN1C(=O)N(c2ncc(C#Cc3ccc(F)cc3)cn2)CC1(C)C +COc1ccc(-n2nc(C(N)=O)c3c2C(=O)N(c2ccc(N4CCCCC4=O)cc2)CC3)cc1 +COc1cccc(S(=O)(=O)N2CCN(C(=O)CN(C)c3ccc(Cl)c(Cl)c3)C(CN3CCCC3)C2)c1 +CN(C)CCC(=O)Nc1ccc2nc3c4[nH]c5ccccc5c4ccn3c(=O)c2c1 +Cn1ccc2ccc3c4[nH]c5c(CCN6CCSCC6)cccc5c4c4c(c3c21)C(=O)NC4=O +CN(C)c1ccc(-c2ccc(-c3ccc(O)cc3)s2)cc1 +Fc1ccc2c(c1)-c1ccnc3[nH]c(C4=CCNCC4)c(c13)CO2 +Cc1nn(C)c2ccc(N3CCN(C(=O)C4CCCCC4C(=O)NC4(C#N)CC4)C(C)C3)cc12 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccc4ncccc4c3)cc21 +CCCc1cc(Oc2ccc(S(C)(=O)=O)cc2)ccc1OCCCOc1ccc2c(c1)OC(CC)(C(=O)O)CC2 +CC(C)(C)OC(=O)N1CCc2c([nH]c3cccc4c(=O)[nH]nc2c34)C1 +O=C(Nc1ccc(F)cc1F)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)c1ccccn1 +O=C1C(O)c2cc(Cl)ccc2N1CCn1cc(COc2ccc(CNNc3ccnc4cc(Cl)ccc34)cc2)nn1 +Cc1cc(C(F)(F)F)c(N)c(=O)n1CC(=O)NCc1cc(Cl)ccc1OCC(=O)NCCCN(C)C +Nc1nccn2c(C3CCC3)nc(-c3cccc(OCc4c(F)cccc4Cl)c3)c12 +COC(=O)c1c(NC2CCN(Cc3ccc4c(c3)OCO4)CC2)c2cc(Cl)ccc2n(C)c1=O +O=C1c2ccc(OCC3CCCO3)cc2CCN1C1Cc2ccc(CNC3CCCCC3)cc2C1 +COc1ccccc1CNC(=O)c1cc(C2CC2)nc2c1cnn2C(C)C +CCN1CCN(c2ccc3c(Nc4cc(CCc5c(Cl)c(OC)cc(OC)c5Cl)[nH]n4)ncnc3c2)CC1 +COc1cc(Sc2c(-c3cc4ccccc4o3)[nH]c3ccccc23)cc(OC)c1OC +O=C(O)c1cc(S(=O)(=O)Nc2ccccc2C(=O)O)ccc1O +O=c1c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc2n1NCc1nccs1 +CCCCCCCCN1NCN(c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)C1=O +O=c1[nH]c2cc(Nc3ccc(F)cc3F)ccc2n1CC1CCCCC1 +N=C(N)c1ccc(CN2CCN(Cc3nc4cc(Cl)ccc4[nH]3)CC2=O)cc1 +CC(=O)NC(Cc1ccccc1)C(O)CNC1CC2(CCC2)Oc2ncccc21 +COc1cc(CNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)cc(OC)c1 +CC(C)c1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cc1 +CN1CCN(c2ccc(Nc3nc4c(CCc5ccccc5N(C)S(C)(=O)=O)cccn4n3)cc2)CC1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCC(F)(F)CO2)C(=O)C1CCN(Cc2ccccc2)C1 +COc1cccc2[nH]c3c(c12)CC1c2cc4c(cc2CCN1C3)OCO4 +Fc1cc(F)c2[nH]cc(Cc3c[nH]c4c(F)cc(F)cc34)c2c1 +CCCN(CCCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12)CCCNc1c2ccc(Cl)cc2nc2ccc(OC)cc12 +N#CC(=Cc1ccc2[nH]ccc2c1)c1nc2ccccc2[nH]1 +Cn1c(=O)c(S(=O)(=O)c2ccc(O)cc2)cc2cnc(Nc3ccc4[nH]ccc4c3)nc21 +NC(=O)c1cccc2c1C(=O)N(c1ccc(CN3CCCC3)cc1)C2 +COc1cccc(C(=O)Nc2ncc(Cc3cccc(C(F)(F)F)c3)s2)c1 +CN1C(=O)C(NC(=O)CCCCCCC(=O)NO)N=C(c2ccccc2)c2ccccc21 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c(-c2ccncc2)nn1CC(=O)O +NC(=O)c1ccc(OC(=O)NCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)c2ccccc12 +COC1CCC(Nc2ccc3ncc(-c4cccc(Cl)c4)n3n2)CC1 +Cn1c2ccccc2c2[nH]cc3nc4ccccc4c-3c21 +CC1(C)C2CC(CC=CCCCC(=O)O)C(NC(=O)c3csc4c3CCCC4)C1C2 +Cc1cc(-c2nc(-c3ccc(Cl)c(C(F)F)c3)n3c2CCOCC3)ccn1 +Cc1c(NS(=O)(=O)c2ccc(-c3cccc(C(C)(C)N)c3)cc2)c(CC(C)C)nn1C +NCc1ccc(-c2ccc3ncc(-c4ccncc4)n3n2)cc1 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+O=C(NCC(F)(F)F)C1(CCCCP(=O)(OCCCc2ccccn2)OCCCc2ccccn2)c2ccccc2-c2ccccc21 +COc1ccc2nc(-c3ccc(Cl)cc3)n(C(C(=O)NC3CCCCC3)C3CCCCC3)c2c1 +NC(=O)c1cnc2cc(-c3ccncc3)ccc2c1Nc1ccc(F)cc1 +CC1COc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc2N1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(Cl)c(Cl)c3)CC2)nc1 +COC(=O)c1sc2ncnc(Nc3cccnc3OC(C)C)c2c1C +O=C(NCCCCl)NCC1OC(n2cc(Cc3ccc(C4CC4)cc3)c3c(Cl)cccc32)C(O)C(O)C1O +CCC(NC(=O)c1c(Br)c(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(C(F)(F)F)nc1 +CC(C)(C)c1cnc(CSc2cnc(NC(=O)Cc3ccc(OCCCCC(=O)NO)cc3)s2)o1 +CC1=CC23C(=O)C(C=C(CO)C(O)C2(O)C1OC(=O)c1c(N)cccc1Cl)C1C(CC3C)C1(C)C +Cc1ccccc1-n1c(Cn2nc(C#CC(C)O)c3c(N)ncnc32)cc2cccc(C)c2c1=O +CN(C(=O)CN(CC(=O)NCCCN1CCCC1)c1cc(Cl)ccc1Oc1ccc(Cl)cc1)C1Cc2ccccc2C1 +COC(=O)C1C2CC3CCC1N3CC2=CC#Cc1cc(F)ccc1F +COC1CCC2(CC1)Cc1cc(F)c(-c3cccc(C#N)c3)cc1C21N=C(N)N(C)C1=O +O=Cc1c(OCCCCN2CCN(c3cccc(Cl)c3Cl)CC2)nn2ccccc12 +CCS(=O)(=O)N1CCN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)CC1 +COc1ccc(O)cc1-c1cccc(C(CC(=O)O)c2nccs2)c1 +CCC(C)C(N)C(=O)N1CCC1C(=O)c1nc2ccccc2s1 +CC(C)Oc1ccccc1OCCN1CCC(NS(=O)(=O)c2cc(Cl)ccc2F)C1 +CC(C)(C)NS(=O)(=O)c1cncc(-c2ccc3nc(NC(=O)NCCc4ccccc4)nn3c2)c1 +COc1ccc(Nc2ncc(Cl)c(Nc3cccnc3C(N)=O)n2)cc1N1CCN(C)CC1 +Cc1cncn1CCCN=C(C[N+](=O)[O-])Nc1ccc2c(c1)OCCO2 +O=C(NCC(c1ccccc1)c1ccnnc1)c1ccc(Cl)cc1Cl +CCNC(=O)Nc1nc2ccc(-c3ccnc(C)c3)cc2[nH]1 +CC1(C)Oc2ncnc(N)c2C=C1c1ccc(C2CCC(CC(=O)O)CC2)cc1 +COCc1nc(CN(C(=O)CCC(C2CCCCC2)N2Cc3cc(Oc4ccccc4)ccc3N=C2N)C2CCCCC2)cs1 +CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1cc(Cl)c(C(=O)O)cc1Cl +CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3CNc3ccccc3)cc2)cc1 +CCCCS(=O)(=O)N1CC2CCC1C(C(=O)Nc1ccc(Cc3ccccc3)cc1)C2 +COCC1CCC(C)C(O)(C(=O)C(=O)N2CCCCC2C(=O)OCc2ccccc2)C1 +C=C(C)Cn1c(SCC(=O)c2cccs2)nc2sc3c(c2c1=O)CCCC3 +CC(C)C(C)NC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=C(NC1CCC(CCN2CCN(c3cccc4c3OCO4)CC2)CC1)C1(O)CCCCC1 +CCOC(=O)c1c(-c2nc(CCO)no2)c(CCO)n2nc(N3CCOCC3)cc(-c3ccccc3)c12 +COc1ccc(C(=O)N(C)C2(c3ccccc3)CCC(c3ccccc3)(N(C)C)CC2)cc1 +CC(C(O)c1ccc(O)cc1)N1CCC(O)(Cc2ccccc2)CC1 +O=S(=O)(c1ccccc1)c1cc2c(N3CCNCC3)cccc2[nH]1 +COc1ccc(N=c2oc3cc(O)ccc3cc2C(=O)Nc2ccccn2)cc1 +OC(CNC(Cc1ccccc1)(c1cc(F)cc(OC(F)(F)C(F)F)c1)c1ccc(Cl)cn1)CC(F)(F)F +CCOC(=O)c1ccc2c(c1)C1C=CCC1C(C(=O)O)N2 +CC12CCC(O)CC1=CCC1C2CCC2(C)C(c3n[nH]cc3C#N)=CCC12 +Cc1nc(N2CCC(NC(c3cccnc3)c3ccc(Cl)cc3F)CC2)no1 +COc1ccc(C(=O)c2csc(S(N)(=O)=O)c2)cc1 +CC1(C)CC=C(c2cc(Cc3nnn[nH]3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +CNc1nc(C2c3cc(F)ccc3CN2C(=O)C(O)C(O)C(=O)NC(C)c2ccc(-n3cccn3)cc2)cs1 +CNC(=O)C1CCC(Nc2cc(=O)n(C)c3ccc(-c4cncs4)cc23)CC1 +Oc1ccc(N2CCN(Cc3cnn(-c4ccc(Cl)cc4)c3)CC2)cc1 +O=C(Nc1cccc(-c2ccnc3c(-c4ccc(CN5CCCC5)cc4)cnn23)c1)c1cccc(C(F)(F)F)c1 +O=C(NCC1CCO1)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CC(Nc1ncnc(N)c1C#N)c1nn2c(C(F)(F)F)ccc2c(=O)n1-c1ccccc1 +O=C(CCCN1CCN(c2ccc(F)cc2)CC1)NC1c2cc(F)ccc2SCC2CCCCC21 +Cc1cc(-c2ccc(NCc3ccc(Cl)cc3-c3ccc(C(=O)NCCC(=O)O)nc3)cc2)ccc1F +Cc1nn(Cc2ccc3c(c2)OCO3)c(=O)c2nc(C)n3nc(-c4ccccc4)cc3c12 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3nccc4[nH]ccc34)c2)c2cncnc21 +CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1ccc(OC(F)(F)F)cc1)c1ncccc12 +Cc1ccc(C(=O)NC(C)(C)CO)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CCCCn1c(=O)c(C(=O)NC2CCC(C)CC2)c(O)c2cccnc21 +Cc1cc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)OCC3F)c2)nn1C +O=C(NCCCCc1cccnc1)c1ccc2nc3cc(Cl)ccc3c(=O)n2c1 +CCc1ncnc(-c2ccc(C(=O)N3CCc4ncccc4C3)c(F)c2)c1C#Cc1ccc(N)nc1 +CC1(C)CC2CC(C)(CN2C(=O)c2ccc(-c3ccc(-c4cccc5cccnc45)cc3Cl)cc2Cl)C1 +CCS(=O)(=O)Nc1cccc(N(Cc2ccccc2)Cc2ccccc2)c1C +COc1c(OCCN2CCCCC2)cc(F)c2c(-c3ccc(O)c(Cl)c3)nc3[nH]nc(C)c3c12 +CCCCCCCC(=O)CCCCCCC=CC(C(=O)NC(Cc1cccs1)C(=O)O)C(O)(CC(=O)O)C(=O)O +OCc1nccc(N2CCN(c3ccc4ccccc4n3)CC2)n1 +O=C(NC1CCN(Cc2ccccc2)C1)c1cccc(-c2ccsc2)c1 +O=C(NCC1(CC2CC2)C2CN(S(=O)(=O)CC3CC3)CC21)c1ccc(Cl)cc1Cl +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4COc5ccccc5C4)ncc23)ccn1 +Cc1cccc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)n1 +Clc1cccc(-c2ncccc2CC(c2cccnc2)c2cccnc2)c1 +c1ccc(-c2nc(NC3CCCCC3)cc(C3CC3)n2)nc1 +COc1cc(CNc2nc(-c3cccc(C)n3)c(-c3ccc4ncnn4c3)s2)cc(OC)c1 +Cc1oc(-c2ccccc2)nc1CCNc1ccc(CC(C(=O)O)n2cccc2)cc1 +CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCC(=O)OC(C)(C)C)CC1 +Oc1ccc(-c2cc(-c3ccccc3)c(-c3ccc(O)cc3F)s2)c(F)c1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccc4cnccc4n3)n[nH]c2C1(C)C +Cn1cc(-c2ccc(-c3cncc4ccc(N5CCOC5=O)cc34)cc2)cn1 +COc1cc2nc(-c3ccccn3)n(-c3ccc4c(N)nc(N)nc4c3)c2cc1OC +Cc1ccc(Sc2cccc3[nH]c4nc(N)nc(N)c4c23)cc1 +CCCN(C)C(=O)OC1=C(c2ccccc2)Oc2ccccc2-n2cccc21 +CCCC(CC1(C(=O)NC2CC2c2ccccc2)CCCC1)C(=O)O +O=C(C=Cc1ccc(CNc2nccc(-c3cccnc3)n2)cc1)NO +COc1c(C)cc(-c2ccccc2)cc1C(=O)NC1CCCCCC1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OC(C)CN(C)C)c(C(=O)O)c2)c1 +CC(Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1ccc(CNC(C)(C)C)cc1C(F)F +COc1cc2ncnc(Oc3ccc(NC(=O)NC4CC4)c4ccccc34)c2cc1OC +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1(S(=O)(=O)c2ccccc2Br)CCCCC1 +O=C(O)Cc1nn(Cc2nc3ccccc3s2)c(=O)c2ccc(Cl)cc12 +CC1CC(=O)NN=C1c1ccc2c(c1)CCC(=O)N2C +CCn1c2ccccc2c2cc(NC(=O)N3CCOCC3)ccc21 +O=C1C=CC2(C=C1)OCC(c1cccc(-c3ccc(F)cc3)c1)O2 +Fc1ccc(NC(=S)Nc2cccc(C(F)(F)F)c2)cc1Cl +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(N3CCCC3=O)cc2n1Cc1ccccc1 +O=C1NC(=S)N(C2CCCCC2)C(=O)C1=CNNC(=O)c1ccccc1 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-n3cccn3)ccnc12 +O=c1ccn(CCCS(=O)(=O)N2CCCC2C(O)(c2cccc(F)c2)c2cccc(F)c2)c(=O)[nH]1 +COc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc([N+](=O)[O-])ccc1Cl +O=C(NCC1(O)CC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +CCN(CC)CCCNC(=O)C1CN(S(=O)(=O)c2ccc(OC)c3ccccc23)c2ccccc21 +O=C(NO)C1CCC(O)CN1S(=O)(=O)c1ccc(OCc2ccccc2C(F)(F)F)cc1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(Cl)cc1-c1cc(N2CCC2)ncn1 +O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCN3CCCCC3)c2=O)cc1 +COc1cccc(CCCCCCC(=O)c2ncc(-c3ccccn3)o2)c1 +CCCn1c(=O)c2nc(-c3ccco3)[nH]c2n(CCC)c1=S +Cc1ccc(NC(=O)Nc2ccc3c(-c4cnco4)c[nH]c3c2)cc1 +OC1CC(OCc2ccc(F)cc2)CCC1N1CCc2ccccc2C1 +Cc1ccc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1-c1nc2cc(N(C)CCO)ncc2[nH]1 +CC1CCN(C(=O)C(CCn2cccc2C#N)NS(=O)(=O)c2ccc3cc[nH]c3c2)CC1 +COc1cc2c(cc1OC)C(=O)N1C=C(c3ccc4ncccc4c3)CC1C(S(=O)(=O)O)N2 +COc1ccc2ccc(OC3CCN(c4ncnc5cc(OC)c(OC)cc45)C3)cc2c1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CC(CC(=O)c1ccccc1)C(=O)NC1c2ccccc2CC1O +CC(Cc1c[nH]c2c(OC(C)C)cccc12)NCC(O)c1cccc(NS(=O)(=O)c2cccs2)c1 +COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccccc2F)cc1 +CC(NC(=O)c1cc(-c2nc3cc(F)ccc3[nH]2)cc(N(C)S(C)(=O)=O)c1)c1ccccc1 +Cc1oc(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)Nc2ccccc2F)nc1C(=O)O +N#Cc1ccc(Cn2cncc2COCc2ccc(C#N)cc2-c2ccc3c(c2)OCO3)cc1 +CC(C)(N)C(=O)N1CCC(CCn2c(Sc3cc4c(cc3Br)OCO4)nc3c(N)ncnc32)CC1 +Cc1cc2c(c(Oc3cccc(NS(=O)(=O)c4ccc(Cl)cc4)c3)n1)C(=O)NC2=O +Cc1nc(N)ccc1CNC(=O)C1C=CCn2c(=O)n(C(CSc3ccc(Br)cc3)C(=O)OC(C)C)c(=O)n21 +CN1CCC(Oc2ccc(-c3n[nH]c4ccc(C(=O)NC(c5ccccc5)C5CC5)cc34)cc2)CC1 +CN1CCN(CCN(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)C2CCC3(c4cccc(C#N)c4)CC23)CC1 +COc1ccc(CCCO)c(Nc2nc3ccccc3nc2NS(=O)(=O)C2CCNCC2)c1 +[C-]#[N+]c1ccc(C2CN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3CO2)cc1F +O=C(Cc1cccc2ccccc12)NCCCCCC(=O)N1CCC(CNCCCCNCC2CCNCC2)CC1 +CC(C)(C)OCCN1CCC(CNC(=O)c2cc(Cl)cc(Cl)c2)CC1 +CCC(C)n1ccnc1C=CC=CC(=O)C=Cc1ccccn1 +O=C(CCc1ccc2ccccc2c1)Nc1ccccc1C(=O)O +O=S(=O)(c1c(Cl)nc2sccn12)n1ccc2ncccc21 +NC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(C4CC4)n3)CC3CC32)c2ccccc12 +N#CC1(NC(=O)C(CS(=O)(=O)Cc2ccccc2-c2ccccc2)NC(c2ccc(F)cc2)C(F)(F)F)CC1 +CCc1cc(-c2noc(-c3cc(OC4CCCC4)cc(C)n3)n2)cc(C)c1OCC(O)CNC(=O)CO +CNC(=O)Nc1ccc(-c2nc(N3C4CCC3COC4)nc3c2C(=O)N(C)CC(C)(C)O3)cc1 +CCc1nc2c(n1C(C1CC1)C1CC1)C(=O)N(C)CN2c1ccc(Cl)cc1Cl +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1CCCC(=O)NCCO +NC1=NC2(c3ccc(F)cc3F)COC(c3ccn(C4CC4)n3)CC2CS1 +COc1cccc(CNC(=O)c2sc3nc(C)cc(C)c3c2N)c1 +CCS(=O)(=O)c1nc(S(=O)(=O)c2ccc(Cl)cc2)c(N2CCc3ccccc3C2)s1 +Cc1ccc(C(=O)Nc2ccc(OC(CCN(C)C)c3ccccc3)cc2)cc1Cl +CN(C)c1ccc2c(COc3ccc(Cl)c(Oc4cc(Cl)cc(C#N)c4)c3)noc2n1 +Cc1ccc(C=CC(=O)Nc2ccc3nc(N(C)CCN(C)C)cc(C)c3c2)cc1 +CNc1ncc2cc(-c3cc(NC(=O)Nc4cccc(C(F)(F)F)c4)ccc3C)ccc2n1 +CC(C)(C)c1ccc(Oc2ccc(-c3cc(C(=O)O)c4cc(F)ccc4n3)cc2)cc1 +NC1=NC2(c3ccc(F)cc3F)COC(C(F)F)CC2CS1 +CC1CC2=C(C3Oc4c(O)ccc5c4C34CCN(CC3CC3)C(C5)C4(O)C2)N(Cc2ccccc2)C1=O +Cc1c(NC2CCCCC2)cccc1-c1ccc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)nc1C(=O)O +O=C(Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1)c1ccccc1Cl +C#CCN(Cc1ccc2nc(C)n(C)c(=O)c2c1)c1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1 +N=C(N)Nc1ccc(C(=O)Oc2ccc3nc(C(=O)N(CC(=O)O)Cc4ccc(CC(=O)O)cc4)ccc3c2)cc1 +NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3ccc(I)cc32)cc1 +CCC(CC)c1nc2c(-c3ccccc3)cc(-c3ccccc3)nc2[nH]1 +Cc1nsc(-c2nnc3n2CCN(C(=O)c2ccc(F)cc2)C3(C)C)n1 +CNC1CCN(c2nc(N)nc3c2Cc2ccccc2-3)C1 +Cc1ccc2c(O)c3c(c(O)c2n1)C(=O)N(Cc1cccc(Br)c1)C3=O +O=C1OC2(CCC(c3nc4cc(OC(F)(F)F)ccc4[nH]3)CC2)CN1c1ccc(F)cc1 +COc1ccc(C#CCN(c2cc(OC)cc(OC)c2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)nc1 +O=C(COc1ccccc1)NC(c1ccccc1)c1cc(Cl)c2cccnc2c1O +CCc1nc(C)c2c(NC(C)=O)nc3ccc(OC)nc3n12 +Cc1cc(N2CCCCC2)nc(NCCCNc2ccnc3cc(Cl)ccc23)n1 +COCCOc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +CCCCN(C)C(=O)C(CC1CCCCC1)NC(=O)C(CC(C)C)NC(=O)Cc1ccc(F)cc1 +N#CC1(NC(=O)C2CCCCC2C(=O)N2CCc3[nH]c4c(F)cccc4c3C2)CC1 +O=C(O)CCC(CP(=O)(O)CC(Cc1ccccc1)C(=O)O)C(=O)O +CCCc1c(OCc2ccc(C(=O)O)cc2F)ccc(C(C)=O)c1O +CCS(=O)(=O)c1ccc(Oc2ccc(F)cc2F)c(-c2cn(C)c(=O)c3cncn23)c1 +O=C(c1cncs1)c1nc(NCc2cccnc2)nc2ccsc12 +CC(C)CN(NC(=O)c1ccccc1Oc1ccccc1)c1nc(C#N)ncc1Br +COc1ccc(C=CC(=O)OCC(=O)NCc2ccco2)cc1OC +O=C(O)C1CCCN(CCC=C(c2ccccc2F)c2ccccc2F)C1 +O=C(CN(c1ccc(Cl)cc1)S(=O)(=O)c1ccccc1)NN=C1C(=O)Nc2ccccc21 +Cc1cccc(-c2nc(Nc3ccc4ncsc4c3)c3ccccc3n2)n1 +CCCn1c2ccccc2c2cc(C(=O)N3CCCCC3)ccc21 +CCOC(=O)c1c(C)[nH]c(C(=O)NN=Cc2cc([N+](=O)[O-])ccc2O)c1C +CC1CCN(C2CC(Oc3ccc(Cl)cc3)c3c(c4ccccc4n3CC3CCNCC3)C2=O)CC1 +O=C(O)CCc1ccc(OCc2ccccc2-c2ccc(Br)cc2)cc1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(-c2ccncc2)nc1OCC#CCO +COc1cccc(Nc2cc(C)nc3ccc(NC(=O)Nc4ccc(N(CCCl)CCCl)cc4)cc23)c1 +Nc1ccc(N2C(=O)N(c3ccc(N)c(F)c3)C(Cc3ccccc3)C(O)C2CCc2ccccc2)cc1F +N#Cc1ccc2[nH]cc(C3CCC(N4CCOCC4)C3)c2c1 +CCCCc1nc2cccc(COC)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COCC1CCN(c2nc(NCCN3CCCC3)nc3scc(-c4ccccc4)c23)CC1 +CN(C)C(=O)c1ccc2c(c1)OCC(N1CCc3c(nn(Cc4ccccc4)c3Cl)C1=O)C(=O)N2C +CCOC(=O)CNP(=O)(COc1cc(C)c(C)c2c1-c1ncsc1C2)NCC(=O)OCC +Cc1ccc([N+](=O)[O-])cc1S(=O)(=O)N(C)N=Cc1cnn2ccc(I)cc12 +CC1CCC(Oc2ncccc2C(C)(C)O)CN1C(=O)c1ccsc1-n1nccn1 +Nc1nonc1-c1nc2cncc(C(=O)N3CCC(N)C3)c2n1CC1CC1 +Cn1cc(-c2cccc(-c3ncc(-c4cnn(C5CCCN(S(C)(=O)=O)C5)c4)cn3)c2)cn1 +C=CC(=O)Nc1cccc(CNc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2C(F)(F)F)c1 +CC(C)CCNc1nc2c(S(=O)(=O)c3ccc(Br)cc3)nnn2c2ccsc12 +Cc1cc(C)n(-c2cc(NC(=O)CCN(C)C)nc(-c3ccc(C)o3)n2)n1 +COC12CCC3(CC1COc1ccc(-n4ccnc4)cc1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(-c4cccc(Cl)c4)c23)c1 +O=C(O)Cc1cc(Cl)c(Oc2ccc(O)c(-c3cccc(-c4ccccc4)c3)c2)c(Cl)c1 +CS(=O)(=O)N1CCN(c2ccnc(-n3ccnc3)n2)C(CC(=O)NCc2ccc3c(c2)OCO3)C1 +N#Cc1ccc(-c2n[nH]c3c2Cc2ccc(OCCCCN4CCOCC4)cc2-3)cn1 +CC(=O)c1cncc(-c2cccc(C(C)Nc3cc(-c4ccc5occ(C)c5c4)nc(C)n3)c2)c1 +CSCCC(NC(=O)c1ccc(CN(c2cccnc2)S(=O)(=O)c2ccccc2)cc1-c1ccccc1C)C(=O)O +Cc1cc2c(cc1Cl)N(C(=O)Nc1cnc(Oc3cccnc3C)c(Cl)c1)CC2 +COc1ccnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +COc1ccc(NC(=N)c2ccsc2)cc1CSC1CCCC1 +COc1ccc2nccc(NCCCCCCCNc3ccnc4ccc(OC)cc34)c2c1 +CN(C)c1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1 +N#CC1CN(C(=O)OCCC2CC2)CCC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +CC(C)N1C2CCC1CC(c1cc(-c3ccc(F)cc3Cl)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c1)C2 +CC(C)Oc1ccc(Cc2ccccc2)cc1C(=O)CC(=O)C(=O)O +Cc1cc(S(=O)(=O)n2cc(NC(=O)c3ccccn3)cn2)ccc1Cl +CC1=C(C(=O)OCc2ccc3c(c2)OCO3)C(c2ccoc2)NC(=O)N1 +COc1ccc(-c2cc3c(NC4CCC(C)(N)C4(C)C)c(C(N)=O)cnn3c2)cn1 +Cn1c(COc2ccc(C(C)(CCC(=O)O)c3ccc(OCc4ccc5ccccc5n4)cc3)cc2)nc2ccccc21 +COc1ccc(C2C(Oc3ccccc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1N +Nc1nnc(-c2ccc3[nH]cc(-c4cccc(OC5CCC5)n4)c3c2)s1 +COCCOc1ccc(-c2ccc3nc(C(C(=O)NCCS(N)(=O)=O)S(C)(=O)=O)sc3c2)cc1 +Cc1nc2c(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(C(=O)N(C)C)cc4)c3Cl)cccn2c1Br +O=C(O)c1cncc(Oc2cnc(NC(=O)C(OC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)c1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)cc2[nH]c(=O)oc12 +CC(Oc1ccc2ccccc2c1)C(=O)NNC(=S)NC(=O)c1ccco1 +COc1cc(C(=O)N2CCOCC2Cc2cccc(-n3nccn3)c2)c(-n2nccn2)cc1C +CNC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)C4CC4)ccc3C)cc1CC2 +COc1ccc2c(c1)OCC(N1CCC(O)(c3ccc(F)cc3)CC1)C2O +CCCCC(CN(O)C=O)C(=O)NC(C(=O)c1ccc(N)cc1)C(C)(C)C +O=C(O)C(Cc1c[nH]c2ccccc12)NC(=O)C(CS)c1cccc(-c2ccccc2)c1 +CC1CN(CCc2ccncc2)CCN1S(=O)(=O)c1ccc(C(C)(O)C(F)(F)F)cc1 +CC(C(=O)NCC(F)F)c1ccc(OC2CCN(c3nc(N(C)C)ncc3F)C2)cc1 +CN(C)CCCOc1ccc2c(=O)cc(-c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)oc2c1 +COc1ccc(CN2C(=O)C(=O)c3cc(C=CC(=O)N4CCCC4)ccc32)cc1 +COc1ncc(Nc2ncc(CN3CCOCC3)cc2-c2nc(C)nc(N)n2)cc1NS(C)(=O)=O +CCCCC(C)OC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +O=C(Cc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Cl)cnc32)CC1 +CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4c(OC)cc(C)nc34)c2Cl)cc1 +CN(Cc1cccc(B(O)O)c1)c1ccc(C(=O)Nc2ccc(F)cc2)cn1 +Cc1ccc(OCc2ccc3c(c2)CCN(C2COC2)C3)c(-c2cccc(N3CCC4(C(=O)O)CC4C3)n2)c1 +CC(Oc1cccc(Cl)c1)C(=O)N(CC1CCCN1)c1ccccc1 +Cn1c(=O)c2nc(-c3ccc(S(=O)(=O)Oc4cccc([N+](=O)[O-])c4)cc3)[nH]c2n(C)c1=O +CC(=O)N1CCC(Cn2c(C(C)(C)C)nc3cc(S(=O)(=O)c4ccncc4)ccc32)CC1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN2CCCCCC2)C1=O)c1ccccc1 +O=C(Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C1N(Cc2cccc3ccccc23)CCCC12CCN(c1nc3ccccc3[nH]1)CC2 +CCn1nc(-c2cccc(-c3ccccc3C(=O)O)c2)cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O +CCC(N)COc1cncc(-c2cc3c(cnc4cc(OC)c(OC)cc43)c(N)n2)c1 +O=S(=O)(NCCCCN1CCN(c2noc3ccccc23)CC1)c1ccc2cc(Cl)ccc2c1 +Cc1c(N(Cc2cc3cccc(Cl)c3n2C)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +CCc1cc(Nc2cc(=O)n(CCN3CCN(C(=O)c4ccccc4)CC3)c(=O)[nH]2)ccc1C +O=C(c1ccc(F)cc1Cl)N1CCn2c(nnc2-c2cccc(Cl)c2)C1 +COc1cc(N2CCN(CC(C)O)CC2)c(F)cc1Nc1ncc2ccc(-c3ccccc3N(C)S(C)(=O)=O)n2n1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc([N+](=O)[O-])o1 +C#CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +C=CCN1CCN(c2nc(NCCc3ccc(O)cc3)nc(N(C)CCCc3ccc(Cl)cc3)n2)CC1 +CCN(CC)c1ccc(C=CC(=O)c2ccc(OC(=O)C(C)C)c3c2OC(C)(C)C=C3)cc1 +CCOc1ccc(-c2nc(C)c(C(=O)O)[se]2)cc1C#N +O=C(c1ccc(O)c(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)c1)N1CCN(c2ccc(Cl)cc2)CC1 +COC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCc1ccccc1 +CS(=O)(=O)c1cccc(C(=O)Nc2nc3ccccc3n2CCCO)c1 +CS(=O)(=O)c1ccc(CC(NC(=O)c2c(Cl)cc3c(c2Cl)CCN(C(=O)c2ccc(Cl)cc2)C3)C(=O)O)o1 +CSc1nnc(NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3-c3ccnn3C)c(C#N)c2)s1 +CC(C)c1ccc2oc(NC(CN3CCOCC3)c3ccccc3)nc2c1 +Cc1cc(Cn2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cccc(Cl)c2F)C3=O)n(C)n1 +Cn1c(=O)sc2cc(CCN3CCN(c4cccc(C(F)(F)F)c4)CC3)ccc21 +CC(=O)Nc1cccc2c3c4c(cccc4cc12)C(=O)N(CCN(C)C)C3=O +COc1ncccc1NC(=O)N1CC(C)N(c2ccc(C#N)c(C(F)(F)F)c2)CC1C +COc1ccccc1N1CCN(CCCCC(=O)NCc2ccccc2-c2cccc(F)c2)CC1 +CCCC(=O)Oc1cccc2c1-c1cccc3c1C(C2)N(CCC)CC3 +CC(=O)n1c2cc(=O)n(Cc3cccnc3)c(C)c2c(=O)n1-c1ccccc1 +Cc1cc(NC(=O)c2ccc([N+](=O)[O-])o2)ccc1NC(=O)c1ccco1 +Cc1cc(C#N)cc(C)c1Oc1ccnc(NC2CCN(CC(=O)Nc3ccc(Cl)cc3Cl)CC2)n1 +O=C(NCCCCCCS)c1cc(-c2c[nH]c3ccccc23)n[nH]1 +COC(=O)N(NC(=O)c1c(CN2CCCCC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +CC(C)(O)c1csc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)n1 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCNc3ccc(F)cn3)c2)c1 +O=C(c1ccccc1)N1CCN(c2nnc(-c3ccc(Cl)c(Cl)c3)c3ccccc23)CC1 +COc1ccc(-c2cc3[nH]c(=O)c4ccccc4n3n2)c(OC)c1 +O=C(Nc1ccn(S(=O)(=O)Cc2cccc(F)c2)c1)c1ccccn1 +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2ccc(-c3ccccc3)cc2)c(Cl)c1 +CN(Cc1cc2c(s1)c(=O)c(C(=O)NCc1ccc(Cl)cc1)cn2C)CC(O)c1ccc(O)cc1 +COc1ccccc1Sc1nccc(-c2ccc3nc(NC(C)=O)sc3c2)n1 +COc1ccc2c3c1OC1c4[nH]c5ccccc5c4C(C)C4C(C2)N(C)CCC314 +CN(Cc1ccc(C2=NCCN2)cc1)C(=O)COCCN(C)S(=O)(=O)c1cccc(Cl)c1Cl +COc1ccc(OC)c(-c2cccc(C(CC(=O)O)c3ncc(C)s3)c2)c1OC +CN(C)CCCNC(=O)c1ccc2c(c1)CC(c1nc3ccc(-c4cn[nH]c4)cc3s1)CO2 +CN1CCN(CCS(=O)(=O)Nc2ccc(C=C3Oc4c(C(N)=O)cccc4C3=O)cc2)CC1 +COc1cc(-c2cc(NC(C)c3cccc(OCc4ccn(C)n4)c3)nc(C)n2)ccc1C +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(-c3ccc(CO)s3)c2c1=O +CC(=O)Nc1cccc(C2CCN(CCCn3c(-c4ccc(Oc5ccccc5)cc4)nc4ccccc43)CC2)c1 +O=C(Nc1cc(-c2ccc(Br)cc2)[nH]n1)c1cccnc1F +CCC(NC(=O)c1c(N)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +COc1ccc(CNC(=O)c2ccc(Oc3ccc(C#CC4(O)CN5CCC4CC5)cc3)cc2)cc1OC +CCC1(OC(=O)N2CCN(c3ncc(OCc4ccncc4C#N)cn3)C(C)C2)COC1 +O=C(c1c(F)cccc1-n1nccn1)N1CCC2CN(c3cnc4ccccc4n3)C2C1 +Cc1ccc(NC(=O)COc2ccc(-c3nc4c(=O)n(C)c(=O)n(C)c4[nH]3)cc2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1ccccc1F)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1cccc(C)c1Nc1nn(CCCN(C)C)c2nc(Nc3ccccc3)ncc12 +CCCCc1ncc(C(=O)OC)n1Cc1ccc(-c2ccccc2NS(=O)(=O)NC(=O)C2CC2)cc1 +CCCCN(CCCC)C(=O)c1nc(-c2ccccc2)no1 +CC(C)CCNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)nn1 +CCOc1cccc(-c2cc(F)ccc2C2Cc3nc(N)nc(C)c3C(=O)N2)n1 +O=C(Nc1ccc(F)cc1)c1c(NO)cc(-c2cccs2)oc1=O +CN(C)C(=O)c1cc(N2CCN(C(=O)n3nnc4ccccc43)CC2)ccc1[N+](=O)[O-] +CC(C)NC(=O)Nc1nc2nc(NCCCN3CCN(C)CC3)ncc2cc1-c1c(Cl)cccc1Cl +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NCC(=O)O)cc2C)ncn1 +CCC(C)C(NC(=O)C(CC(O)C(CC1CCCCC1)NC(C)=O)C(C)C)C(=O)NCc1ccccn1 +COc1cncc(-c2cc3ncn(C)c(=O)c3c(NC3CC3)n2)n1 +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1ccccc1Nc1ccccc1 +N#Cc1ccc(Nc2cc(Oc3c(Cl)cc(Cl)cc3Cl)c([N+](=O)[O-])cn2)cc1 +CC(C)CN(NC(=O)c1ccc(-c2ccccc2)s1)c1nc(C#N)ncc1Br +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CC[S+]([O-])CC4)ncn3)c2c1 +O=C(NC1CCN(CC2CCCC2)CC1)C(O)(c1ccccc1)C1CCCC1 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NCc3cccc(Cl)c3)cc12 +CN1CCC(CS(=O)(=O)c2ccc3c(c2)nc(CC(C)(C)C)n3CC2CC2)CC1 +Cc1c(-c2ccc(CC(NC(=O)c3c(F)cccc3F)C(=O)O)cc2)c(=O)n(C)c(=O)n1C +Brc1cnc2nc(-c3ccc(C4CNCCO4)cc3)[nH]c2c1 +CCOc1ccc(-c2cc(Cl)cc3c2N2CCNCCC2C3)cc1 +Cc1cc(OCc2nc(-c3cncnc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)NCC3(O)CNC3)cc2F)cn1 +CCC1=C(CC)CC2=C(C1)CC(NCC(O)c1ccc(O)c3[nH]c(=O)ccc13)C2 +O=C(Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)c1ccccc1I +Cc1ccn(-c2ccc(C(=O)N3Cc4cccnc4N(C)c4ccccc43)c(Cl)c2)n1 +Cc1ccc(-c2nc3c(N)cc(C(=O)N4CCCC4)cn3n2)o1 +CC(Oc1cc(F)ccc1Nc1ncnc2cc(N=S3(=O)CCC3)cc(Cl)c12)C(=O)NCC(F)(F)F +Cc1ccc(-c2ccc3ncc4c(c3n2)n(C2CCN(C)CC2)c(=O)n4C)cn1 +O=C(NO)C1Cc2c([nH]c3ccccc23)CN1S(=O)(=O)c1ccc(N2CCOCC2)cc1 +COc1ccc(CN2CCC3(CCc4ccccc4C3=O)CC2)cc1 +CCC(C)C1NC(=O)C(C)NC(=O)C(C(C)C)NC(=O)CC(C=Cc2ccccc2)OC(=O)C(C(C)C)NC1=O +c1ccc(CNc2nc(Cc3ccccc3)cc3c2CCNCC3)cc1 +CCCCN(CC(=O)N1c2ccccc2-n2cccc2C1c1ccc(OC)cc1)C(=O)C(C)C +O=C(NCC12CCC3(O1)C1Cc4ccc(O)cc4C3(CCN1Cc1ccccc1)C2)c1cccc(O)c1 +CNc1nc(Nc2cc(OC)c(C(=O)N3CCNCC3)cc2Cl)ncc1Cl +COc1ccc(CCC2CCN(CCc3ccccc3OC)CC2)cc1 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)N(C)CC(=O)NC(C(=O)C(F)(F)F)C(C)C +O=C(NC1CNC1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)N3CCN(C)CC3)ncc2c1 +Nc1cc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ncn1 +CCOC(=O)c1cnc2c(c1)CC1(O)C3Cc4ccc(O)c5c4C1(CCN3CC1CC1)C2O5 +CCCCC#CCOC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 +CC(C)c1ccccc1Sc1ccc(-c2cc(N3CCC(c4nn[nH]n4)CC3)ncn2)cc1C(F)(F)F +Cc1cc(C)cc(-c2c(O)nc3cc(Cl)c(C(=O)Nc4cc(C)nc(C)n4)cc3c2OCCC2CCCCN2)c1 +CCOC(=O)c1cc2cc(-c3cc(C(=O)NCc4ccc(CC(=O)OC)cc4)nn3C)ccc2[nH]1 +O=C(NCC(c1ccc(Cl)cc1)C1CCOCC1)c1cccc(Cl)c1Cl +CCCCCCCCC(O)c1ccc2ccc(C[S+]([O-])c3cccc(C(=O)O)c3)nc2c1 +COc1cccc(C(=O)NN2c3ccc(Cl)cc3N=C(N3CCN(C)CC3)c3cc(Cl)ccc32)c1 +OC12C=C(c3nccc4c3[nH]c3ccccc34)C3CCN(CCCCC=CCC1)CC31CC3C=CCCCCN3C21 +C#Cc1cccc2nc(Cn3nc(-c4cccc(O)c4)c4c(N)ncnc43)n(Cc3ccccc3Cl)c(=O)c12 +CCOC(Cc1ccc(OCCN2CC=C(c3ccccc3C(F)(F)F)CC2)cc1)C(=O)O +COc1ccc2[nH]cc(Cc3cc4ccccc4[nH]3)c2c1 +CN1C2COCC1CC(NC(=O)c1cn(CC(C)(F)F)c3ncccc13)C2 +CSc1nc(N2CCOCC2)c2cnn(CC(Br)c3ccccc3)c2n1 +O=[N+]([O-])c1cccc(NC(P(=O)(O)O)P(=O)(O)O)c1 +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#Cc1ccc(CNC(C)C)cc1 +Cc1ncc(C[n+]2csc(CCOP(C)(=O)OP(=O)(O)O)c2C)c(N)n1 +COc1cnc2ccc(Cc3nnc4ccc(-c5ccccc5)nn34)cc2c1 +COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(OC(F)(F)F)cc4)cc3F)c(=O)c2cc1Cl +CNC(=O)c1cc(-c2ccnc(C)c2C#Cc2ccc(N)nc2)ccc1Cl +CC1c2cc3c(C(F)(F)F)cc(O)nc3cc2NC(C)(C)C1C +CCOC(=O)CC(NC(=O)c1ccc(NCc2ccc3nc(N)nc(N)c3c2C)cc1)C(=O)OCC +CSCCC(NC(=O)c1ccc(COCc2ccc(-c3ccc(C=O)cc3)o2)cc1-c1ccccc1C)C(=O)O +CCCCCNc1ncnc2c1ncn2C1OC(COS(N)(=O)=O)C(O)C1O +CC1CCC2C(C)C(OCCC3ON3C(=O)c3ccccc3O)OC3OC4(C)CCC1C32OO4 +CNC(=O)c1cccc(S(=O)(=O)Nc2ncc(Br)nc2OC)c1-c1ccccc1 +COc1ccc(Cl)cc1S(=O)(=O)N1CCOc2ccc(C(=O)Nc3ccc(C(=O)O)c(F)c3)cc21 +COc1cc2ncnc(N3CCNC(c4ccc5c(c4)OCO5)C3)c2cc1OC +CCNCC(=O)Nc1ccc(-c2nc(=O)n(CCOC)c3c2oc2cc(-c4ccc5c(c4)CCN(C)C5)ccc23)cc1 +CCn1c(NC(C)C)nc2c(C3CCCN(C(C)=O)C3)csc2c1=O +CN1CCN(CCCc2cccc3c2[nH]c2c4ccc5ccn(C)c5c4c4c(c32)C(=O)NC4=O)CC1 +O=C(Nc1noc2ccccc12)N1CCN(c2nc(-c3ccccc3)cs2)CC1 +CC(C)OP(=O)(OC(C)C)C(Nc1ccc(CNC(=O)C23CC4CC(CC(C4)C2)C3)cc1)C(C)(C)C +COc1cc(OS(=O)(=O)c2ccc(NC(=O)NCCCl)cc2)cc(OC)c1OC +COc1ccccc1C(=Cc1coc2nc(=N)[nH]c(N)c12)C1CC1 +Clc1ccc(-n2nc3c4c(ncc3c2OCC2CC2)CCCC4)cc1 +COc1ccc(-c2cnc3c(N4CC(C)OC(C)C4)snc3c2)cc1OC +c1ccc(C(CCc2nc(CCNCCCCCc3ccncc3)c[nH]2)c2ccccc2)cc1 +Cn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +O=C(Nc1cccnc1)c1ccnc2[nH]c(-c3ccsc3)nc12 +O=C(NCc1cccs1)c1ccc(Nc2nc3ccccc3n(CCc3ccccn3)c2=O)cc1 +CC1CCC(NC(=O)c2cc3cccnc3n(CCCCCCO)c2=O)CC1 +C#CCN(c1ccc2ncc(-c3cnn(C)c3)nc2c1)c1c(F)c(OC)cc(OC)c1F +Cc1cccc(NC(=O)Nc2ccc(-c3cc4ccccc4n3C(N)=O)cc2)c1 +Cc1cc(C)n(-c2nc(Nc3ccccn3)cc(-n3cccn3)n2)n1 +CN1C(=O)CCC2(C)C3CCC4(C)C(C(=O)c5ccc[nH]5)CCC4C3CCC12 +CC1CCC(CN2C3=NCC(C4CCCCC4)N3CC2C2CCCCC2)CC1 +Cc1c(C2CN3CCN(C(=O)C4CCc5nc(-n6cnnn6)ccc54)CC3CO2)ccc2c1COC2=O +Cc1ccccc1OCc1n(CC(=O)OC2CC(C)CCC2C(C)C)c2ccccc2[n+]1C +CC(=O)OC1C(CO)OC(OCc2cn(-c3ccc(S(N)(=O)=O)cc3)nn2)C(O)C1O +N#Cc1cccc(-c2cc(Cl)ccc2C(Oc2cc(N3CCC4(CC3)CNC(C(=O)O)C4)nc(N)n2)C(F)(F)F)c1 +CCN(Cc1ccccc1)c1nc(O)nc(Nc2ccc3ncsc3c2)n1 +CNC(=O)c1ccc(C(=C2CC3CCC(C2)N3CCc2ccccc2)c2ccccc2)cc1 +Cc1cccc(-c2[nH]c(CNc3cc(C#N)cc(CN4CCOCC4)c3)nc2-c2ccc3ncnn3c2)n1 +Cc1cccn2cc(-c3ccc(NC(=O)CCN4CCCCC4)cc3)nc12 +COc1ccc(CN2C(=O)c3cccn3C3(CC(=O)NC3=O)C2=O)cc1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(C(C)(C)C)c2)CCC(N(O)C(C)=O)NC1 +Clc1ccc(-n2nc3c4c(ncc3c2OCc2ccccc2Cl)CCCC4)cc1 +Cc1ccc(N(CC(=O)NN=C2C(=O)Nc3ccccc32)S(=O)(=O)c2ccc(C#N)cc2)cc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3nc(-c4ccc(N5CCNCC5)nc4)ccc3OC)NC(=O)NC1=O)C2 +CC(C(=O)NC1CC1C)c1ccc(OC2CCN(c3nc(N(C)C)ncc3F)C2)cc1 +Cc1c(CC(=O)O)cc2ccc(F)cc2c1-c1ccc(S(=O)(=O)c2c(F)cccc2F)cc1 +Cc1[nH]c2ccc(CCC(=O)O)cc2c1Cc1ccncc1 +O=C(O)CC1CCN(C(=O)c2ccc(NC(=O)c3ccccc3-c3ccccc3)cc2)c2ccccc2S1 +COC(c1ccc(C(=O)N(C)CCCCCCC(=O)NO)cc1)(c1cccc(F)c1)c1cccc(F)c1 +CCCCCCC#CC#CCCCCCCCC(=O)OCC1(CO)CC(=CCC(C)C)C(=O)O1 +CC(Oc1cc2sc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 +CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)c3cc[nH]c3)sc12 +O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)c1ccc(F)cc1 +CN(C)CCn1c(=O)c2ccc3c4c(nn3CCN(C)C)-c3ccccc3-n(c1=O)c24 +Cc1nc(Cn2nc(C3CC3)c3c(NC(=O)c4cnc5cc(OCCN6CCN(C)CC6)ccn45)cccc32)ccc1O +CC(C)CC(NC(=O)CC(c1ccccc1)c1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)O +Nc1noc2cccc(C(=O)Nc3cccc(CNC(=O)Nc4ccc(F)cc4)c3)c12 +NC(Cn1c(=O)c(-c2ccc(CO)cc2)cn(Cc2c(F)cccc2C(F)(F)F)c1=O)c1ccccc1 +CS(=O)(=O)c1cc(-c2cc(C(=O)O)cc3cc(-c4ccc(C(F)(F)F)cc4)ccc23)cs1 +CC(C)(C)NC(=O)C1CC(OCc2ccncc2)CCN1CC(O)C(Cc1ccccc1)NC(=O)OC1CCOC1 +CN(C)CCNc1ccc(Nc2nccc(-c3ccc(N4CCCC4)c(C#N)c3)n2)cn1 +NC(C(=O)N1CC(F)C(F)C1)C1CCC(NC(=O)OCc2ccccc2)CC1 +CCCn1c(NCc2cccc(Cl)c2)nc2nc(C3CCCC3)[nH]c2c1=O +CN(C(=O)c1c(-c2ccccc2Cl)noc1C1CC1)c1ccc(Cl)cc1 +O=C(CC1CC1)N1CCC2(CC1)CN(C(=O)Nc1ccc(C(F)(F)F)cc1)CCO2 +CC(C)NC(=N)c1cccc(-c2cccc(-c3cccc(C(=N)NC(C)C)c3)c2)c1 +CCc1nc(N)nc(N2CCC(O)CC2)c1C#Cc1cnc(C)c(NS(C)(=O)=O)c1 +O=C(NOCC1CC1)c1ccc(F)cc1Nc1ccc(I)cc1Cl +Cc1ccc(-c2nc3c(O)cccc3c(=O)[nH]2)cc1 +COc1ccc(Cc2cc3ccccc3cc2-c2cncc(OC)c2)cc1 +CC(OC1CCC2CNCC2C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1cc2cc(Nc3ccnc4cc(-c5ccc(CNCCOCCO)cc5)sc34)ccc2[nH]1 +COc1ccccc1N1C(=O)CSC1c1cccc(C(=O)NCCc2ccccc2)c1 +O=C(Nc1ccc(OC(F)(F)F)cc1)N1CCC2(CCN(C(=O)C3CCCCC3)CC2)C1 +CCN(C(=O)c1cn(C)c2ccccc12)c1ccnc(NC(C)c2ccccc2)n1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1-c1cc2ccccc2s1)c1ccc(NS(C)(=O)=O)c(F)c1 +CC(C)Nc1nc(-c2ccc(C3(N)CC3)nc2)cc2ncn(C)c(=O)c12 +Cc1ccc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cc(N)cc(C(=O)O)c1 +COc1ccc(C2(C#N)CCN(CC(=O)NO)CC2)cc1OC +CCCCCCC1(c2ccccc2)CC(=O)C(SCc2ccccc2)=C(O)O1 +CCCS(=O)(=O)NCCOc1ccc2c(c1)C(C(C)(C)c1ccc(Cl)cc1)NCC2 +CCCN(CCC)C1COc2cccc(C(=O)NC(C)C)c2C1 +COc1ccc2c(c1)S(=O)(=O)Cc1c(C(=O)N3CCOCC3)nn(C3CCCN(CCN4CC(F)(F)C4)C3)c1-2 +CCCCCCCCCCCCCCC1C(=O)NC(CO)Cc2ccccc2N1C +Cc1nc(NCCCNc2ccnc3cc(Cl)ccc23)nc(-c2ccc([N+](=O)[O-])cc2)c1C(=O)OC(C)C +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(C=CCO)ccn23)c1 +CC(=O)c1nn(CC(=O)N2C(C(=O)NCCCOC(F)(F)F)CC3CC32)c2ccccc12 +COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(I)cc1 +CN(C)C(=O)c1cnn(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)c1 +Cc1cc(Nc2ccc(Cl)cc2)n2nc(S(C)(=O)=O)nc2n1 +Cc1nnc2n1-c1sc(C=Cc3ccc(C4CCCCC4)cc3)cc1C(c1ccccc1Cl)=NC2 +CCc1c(C(C#N)c2cccc3ccccc23)nc(SC2CCCC2)[nH]c1=O +Fc1ccc(CNc2nc(Oc3ccccc3)nc3nc(-c4ccco4)nn23)cc1 +C#Cc1ccc(Nc2c(C(=O)NOCCO)cc(COCCO)c(F)c2F)c(F)c1 +O=C1C(=Cc2ccc(Cl)c(Cl)c2)SC(=S)N1NS(=O)(=O)c1ccccc1 +Cc1ccc(-n2nc(-c3ccc(NS(C)(=O)=O)cc3)cc2NC(=O)c2cnn3cccnc23)cc1 +O=C(CCNS(=O)(=O)c1ccc(C(=O)O)cc1)NO +CC(c1ccc(-c2c(O)ccc3[nH]c(=O)c4sccc4c23)cc1)N(C)C +CCCCCCC1=C(c2ccccc2)C2(OCCCC)CCCC2C1 +CC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cncnc1 +CSCCC(N)CSSCC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)OCc1ccccc1 +CCn1c2ccccc2c2cc(NC(=O)c3cc(OC)c(OC)c(OC)c3)ccc21 +CC1CN(c2scnc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1ccc2ccncc21 +CC(C(=O)NCc1ccc(CC(=O)O)cc1)c1ccc2ccc(OCc3ccc4ccccc4n3)cc2c1 +Cn1c2c(c3ccc(-n4ccc(-c5ccc(C(F)(F)F)cn5)cc4=O)nc31)CCNCC2 +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1COC(=O)C1 +CC(=O)c1ccc(N2CCC(CC(=O)Nc3nc4ccc(C)cc4o3)CC2)cc1 +N=c1c(-c2nc3ccccc3[nH]2)cc(C(=O)c2cccs2)nn1-c1ccccc1 +Cc1cnc(C(=O)N2CC3CC(Oc4cnc(C(F)(F)F)cn4)C2C3)c(-n2nccn2)c1 +CC(C)NCc1ccc2c(c1)[nH]c(=O)c1cccn12 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(C3CCOC3)c2)CCCCC1 +Cc1c(Nc2c(C#N)cnc3sc(C=CC(=O)N4CCN(C)CC4)cc23)ccc2[nH]ccc12 +CCC(=O)Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12 +CCc1cc(S(=O)(=O)N2CC(c3ccccc3)NC2=O)ccc1NC(=O)OCC(C)C +CC1(C(=O)NCc2ccccc2)CC(C(=O)NCc2ccc(C(=N)N)cc2)n2c1c(Cl)nc(NC1CCC1)c2=O +CCCc1nc2c(C)cc(C(=O)NC(C)(C)C)cc2n1Cc1ccc(-c2ccccc2C(=O)Nc2nnn[nH]2)cc1 +CNc1nc(Nc2cc(F)c(C(=O)N(C)C)cc2OC)ncc1C#N +CC1CCN(CCCCCCCC(=O)Nc2cc(CO)cc(Nc3ccnc4cc(Cl)ccc34)c2)CC1 +COc1ccc(N2CCN(CCc3ccc(CN4C(=O)c5ccccc5C4=O)cc3)CC2)cc1 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+COc1cc2[nH]c(C)c(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)c(=O)c2cc1Cl +Cc1ccnc(N2CCCC(Cn3nnc4c(N)nc(C5CC5)nc43)C2)n1 +O=C(O)c1ccc2c(c1)nc(NC1CC1)c1nc(NCc3ccccc3)ncc12 +CN1CCN(Cc2ccc(Nc3ncc(Cl)c(-c4ccc(F)cc4S(=O)(=O)N4CCCC4)n3)cc2)CC1 +CCN(CC)CCNC(=O)c1ccc(NCCN(CC)CC)c2cc3ccccc3nc12 +COc1ccc(C(=O)Nc2ccc(Cn3cc4c(=O)[nH]cnc4n3)cc2)cc1 +Cc1cccc(Nc2nc(NC3CCCNC3)nc3cc[nH]c(=O)c23)c1 +Cn1c(CN2CCN(c3ccc(Cl)cc3)CC2)nc2ccccc21 +CN(C1CCc2c(CC(=O)O)c3cc(F)cc(F)c3n2C1)S(=O)(=O)c1ccc(F)cc1 +O=C(C=Cc1ccc2c(c1)CN(S(=O)(=O)C1CC1)C2)NO +CCn1ccc2cc(C=C3CCc4ccccc4C3=O)ccc21 +O=C1OC(=O)c2cc(NS(=O)(=O)c3cccc4nsnc34)cc3cccc1c23 +CC(C)=CC(=O)Nc1sc(Nc2ccc3ccc(F)cc3c2)nc1C(N)=O +Nc1nccn2c(C3CCC4CCCC(=O)N4C3)nc(-c3ccc(C(=O)Nc4cc(C(F)(F)F)ccn4)cc3F)c12 +CN1CC(NC(=O)c2ccc(N3CC(F)(F)C3)c(OCC3CC3)n2)CC1=O +Cc1ccccc1COc1ccc(S(=O)(=O)N2CCN(C(=O)CN)C(C)C2C(=O)NO)cc1 +N#Cc1cc(-c2ccnc(Nc3ccc(C(N)=O)nc3)n2)cnc1N1CCC(F)C1 +COc1cc2cncc(Cc3coc4ccccc4c3=O)c2cc1OC +CCc1nc2c([N+](=O)[O-])c(OC3CCN(C(C)=N)CC3)ccc2n1Cc1ccc2ccc(C(=N)N)cc2c1 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+O=C(NCC1CCCC1C(O)CCc1ccccc1)c1ccc(OC(F)(F)F)cc1 +Nc1c2c(nc3c1C(c1ccncc1)c1ccc4cccnc4c1O3)CCCC2 +Cc1cc(C)c2oc3cc(=O)c4ncccc4c-3nc2c1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3OC)n1)CCN(CC(=O)N(C)C)CC2 +CN(C)C1CCC(Nc2ncnc3[nH]cc(C4CCCOC4)c23)CC1 +COc1ccc2[nH]c3c(c(C)c4c(O)nccc4[n+]3C)c2c1 +COc1ccc(-c2[nH]c3nc(N)[nH]c(=O)c3c2C#N)cc1 +Cc1cc(Nc2ncc(Br)c(NCC3CCCO3)n2)ccc1O +c1ccc(COc2ccc(-c3cnc4nnc(Cc5ccc6ncccc6c5)n4n3)cc2)cc1 +CC(C)n1ncc2c(C(=O)Nc3cccc(F)c3)cc(-c3cccs3)nc21 +CC(C)OC(=O)C1OC(n2cnc3c(N)ncnc32)C(O)C1O +COC(=O)CC(O)CC(O)C=Cn1c(C(C)C)cc(-c2ccc(F)cc2)c1-c1cccc(Br)c1 +CCC(NC(=O)CCc1ccc(-c2ccccc2)cc1)C(=O)NC(CCC(N)=O)C(N)=O +C=CCN1CC(C)N(C(c2ccc(C(=O)N(CC)CC)cc2)c2cccc(OC)c2)CC1C +O=c1[nH]nc(CCc2ccc(C(F)(F)F)cc2)cc1O +COc1ncc(-c2ccc3ncc4c(c3n2)n(C2CCN(C(C)=O)CC2)c(=O)n4C)cn1 +CCOC(=O)C1(Cc2ccc(OCc3cc(-c4ccccc4)nc4ccccc34)cc2)CC1C(=O)NO +O=C(Nc1ccc(N2CCN(C(=O)C3CC3)CC2)cc1)N1Cc2ccccc2C1 +Cn1c(N)c(C#N)c2cc(Oc3ccc(NC(=O)CN)cc3)ccc21 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+COc1cc2c(cc1OC)C(O)C(N1CCC(c3cccc4c3OCCO4)CC1)C2 +Cc1cc(NC(=O)c2ccc(CN3CCOCC3)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C +COc1cc(OCc2csc(N3CCC(F)(F)CC3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +Cc1cnc2n1CCN(C(=O)c1cccc(C(F)(F)F)c1Cl)C2 +N=C(N)NCCCC(NC(=O)CN1CCN(S(=O)(=O)c2ccc(N)cc2)CC1=O)C(=O)c1nccs1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NC(C)CS(N)(=O)=O)[nH]c3ccc(Cl)cc23)c1 +CCCCn1c(-c2ccc(O)cc2)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 +NC1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5ccccn5)c4)c23)CC1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC(C)c1ccccn1 +CC(C)C#CC(c1ccc(C2(C(F)(F)F)N=N2)cc1)N1CCC(CC(=O)O)CC1c1ccc(C(F)(F)F)cc1 +CCCCCC(O)C#Cc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(OCCC2CC2)cc1F +COc1ccc(C2CC2COc2cc(NCc3nnc(C)s3)n3nccc3n2)nc1 +CC(=O)Oc1cccc(C(=NNC(N)=S)c2cccc(Br)c2)c1 +O=C(Nc1cccc(C(F)(F)F)c1)n1ccc2cc(Oc3ncnc4c3CCNC4)ccc21 +CNCc1cnc2c(C#N)c(-c3ccc(OC)c(OC)c3OC)cc(-c3ccc(F)cc3)n12 +CN(C)c1ccccc1-n1nc(C2CCN(S(C)(=O)=O)CC2)cc1-c1ccc(Cl)cc1 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+CS(=O)(=O)c1ccc(-c2cn(CC(F)(F)F)nc2C2CCC(Cl)(Cl)CC2C(=O)NC2(C#N)CC2)cc1 +Cc1ccc(C)c(CN2CCC(C(=O)N(Cc3cc(Cl)c4c(c3)OCCCO4)CC(C)C)C2)c1 +COc1ccc2[nH]c(O)c(C3=Nc4ccccc4C3=O)c2c1 +CC(=O)c1ccc(OCc2ccc3c(c2)OCO3)cc1OC(CCC(=O)O)c1ccccc1 +Cc1nc(N(C)C2CCc3c(CC(=O)O)c4ccc(Cl)cc4n3C2)c2ccccc2n1 +NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)O)C1OC(CO)C(O)C(O)C1O +Cc1ccccc1-c1ccc(C(C)C(N)C(=O)N2CCC(F)C2)cc1 +CCCN(CCCc1ccc(F)cc1)CC(O)C(C)NC(=O)Nc1cc(CC)cc(-c2nnnn2C)c1 +CC12CCC3c4ccc(O)cc4CC(CCCCC#Cc4ccc5ccccc5c4)C3C1CCC2O +COc1ccc2c(c1)c1c(n2C)CCC1CNC(=O)C1CC1 +NC(N)=NC(=O)c1ccc2c(c1)C(O)c1cccc(CO)c1-2 +COc1cccc2sc(Cn3nc(CC(=O)O)c4ccccc4c3=O)nc12 +CC(C)Nc1nc(Nc2ccc(S(C)(=N)=O)cc2)ncc1Br +CC(=O)NC(C)Cc1ccc(C#Cc2cnc(N(C)C3CCCC3)nc2)cc1 +CCCCNc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1C(F)(F)F +O=C(O)c1c(-c2ccccc2F)c2cc(Cl)ccc2n1Cc1ccccc1 +CCCc1ccc2cc1CN1CCN(CC1=O)Cc1cncn1Cc1ccc(C#N)c(c1)O2 +CN(C)c1ccc(F)c(CCNC(=S)Nc2ccc(Cl)cn2)c1F +COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 +NNc1nc(NC(C2CC2)C2CC2)c2ncn(C3C(O)C(O)C4CC43)c2n1 +CC12Cn3cnc(-c4ccc(F)cc4)c3C=C1CCCC2C(O)c1ccc(F)cc1 +COCCNC(=O)c1ccc(OCc2c(C3CCCCN3)noc2C)nc1 +COc1cc2cncc(Cc3ccc4nc(-c5ccc(CO)cc5)oc4c3)c2cc1OC +CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1)C(=O)c1ccc2nc(N(C)CCN(C)C)oc2c1 +CNC(=O)CN1C(=O)OC2(CCN(C3CCCCCC3)CC2)c2ccccc21 +N#Cc1ccc(S(=O)(=O)N2CCCc3ccc(Oc4cc(-c5nc(C6CC6)no5)cc(Cl)n4)cc32)cc1 +CN(c1ccc([N+](=O)[O-])cc1OC1CCCCC1)S(C)(=O)=O +O=C1c2ccccc2C(=O)N1CCOC(=S)N(C(=O)c1ccnc(Cl)c1)c1ccc(Cl)cc1 +CC(=O)OCC1OC(S(=O)(=O)NCCOS(N)(=O)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O +CC(=O)c1cccc(C#Cc2c(N)ncnc2NC(C)c2nc3cccc(Cl)c3c(=O)n2-c2ccccc2)c1 +CC(=O)OCC(=O)Nc1scnc1C(=O)Nc1nccs1 +Cc1nc2sc(C(=O)NCc3ncccn3)c(N)c2c(C)c1Cl +CC(C)NS(=O)(=O)c1ccc(NC(=S)NC(=O)c2ccc(-c3ccccc3)cc2)cc1 +CNC(=O)c1ccc(CNC(=O)C2CCN(C(C)c3cccc4ccccc34)CC2)cc1 +O=C1Nc2ccccc2C12CC2c1ccc2c(C=Cc3ccncc3)n[nH]c2c1 +CNC(=O)c1coc(C(=O)CCCCCCc2ccccc2)n1 +O=S(=O)(CCC(S)CS)c1ccc(Oc2ccccc2)cc1 +CN(C)CCOc1ccc2c(C#N)cn(-c3ccc(C(=O)O)c(O)c3)c2c1 +CCc1ncnc(NC(C)c2cc3c(cc2O)CCCC3)c1Cl +CCOc1cc(CC(=O)O)ccc1-c1ccc(F)c2c1CN(C(=O)CCc1ccccc1F)CC2 +Cc1ccc(C2(CCN(C)C)CC(c3ccccc3)=NN2C(=O)Nc2ccc(F)cc2)cc1 +CN1CCC(c2ccc(Nc3nc4c(NCc5cccc(S(C)(=O)=O)c5)cccn4n3)cc2)CC1 +CN(C)CCNC(=O)c1cccc2nc3ccc4ccncc4c3nc12 +OC(CCN1CCN(CCCN(c2ccc(F)cc2)c2ccc(F)cc2)CC1)c1ccccc1 +CC(C)(C)NCC(O)COC(=O)c1ccc(C=O)cc1 +CN(CCCc1ccc(Cl)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CC3CC2CN3)n1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2ccsc2)[nH]c1=O +Cn1cc(Br)c(C(=O)N2CCN(CC(=O)c3ccccc3F)CC2)n1 +OC(CNCc1ccco1)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21 +COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCn2ccc3ccccc32)CC1 +O=C(c1ncccc1-n1nccn1)N1CC2CC(Oc3ccc(C(F)(F)F)cn3)C1C2 +O=C(CC(F)(F)F)NCC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +COC(=O)C(CO)Nc1nc2ccccc2n(C2CCN(C3CCCCCCC3)CC2)c1=O +Cc1cc(C(=O)N(c2ccccc2)c2ccccc2)nn1-c1ccccc1C(=O)N1Cc2ccccc2CC1CN +O=C(O)c1csc(-n2nc(-c3ccccc3F)cc2O)n1 +CN1C(=O)Nc2ccc(Br)cc2C12NC(=O)NC2=O +Cc1cc(S(=O)(=O)N(C)C)cnc1-c1ccc2c(c1)CCC(C)N2C(=O)c1ccc(O)cc1O +NC(CC(=O)N1CCN(Cn2nnc3ccccc32)C(=O)C1)Cc1cc(F)c(F)cc1F +CN1Cc2c(C(=O)OC(C)(C)C)ncn2-c2ccc(N=[N+]=[N-])cc2C1=O +CN(c1ncc(F)cn1)C1CCc2c(CC(=O)O)c3cc(Cl)ccc3n2C1 +N#Cc1cnc2ccc(NCc3cccc(N)c3)cc2c1Nc1ccc(F)c(Cl)c1 +COc1ncc(Nc2nc(CN3CCOCC3)ccc2-c2nc(C)nc(N)n2)cc1F +O=C(O)c1ccc(-c2c(C#Cc3nc4ccccc4[nH]3)nc3c(N4CCOCC4)ccnn23)cc1 +O=C(Nc1cccc(C(c2ccc(C(=O)N3CCC3)cc2)N2CCN(Cc3ccc(F)cc3)CC2)c1)C1CC1 +CC(=O)c1nn(CC(=O)N2C(C(=O)Nc3cccc(Br)n3)CC3CC32)c2ccccc12 +Cc1ccccc1-c1nc2ccn(Cc3ccc(Br)cc3)cc-2n1 +CN(c1nc2ccccc2o1)C1CCN(CC2=CCC3CC2C3(C)C)CC1 +Cc1cccc(-c2cnc(NC3=NCC4(CN5CCC4CC5)O3)nc2)c1 +Cc1cccc(NC(=O)NC(CSCc2ccccc2)C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CN(C)CC(Cc1cccc(C(F)(F)F)c1)c1cccc(OCCNS(=O)(=O)c2cnn(C)c2)c1 +CC(NC(=O)C1CC(F)CN1C(=O)Cn1nc(C(N)=O)c2ccccc21)C1CC1(Cl)Cl +CC(NC(=O)Nc1cc2[nH]nc(OCCC3CCCCN3)c2cn1)c1ccccc1 +COc1ccc(OC)c(Sc2ccc3nnc(-c4ccn(C)n4)n3n2)c1 +COc1cccc(-c2ccc(CNC(=O)C3CC3c3ccccc3)c3cnccc23)c1 +OC(COc1cccc2[nH]ccc12)CN1CCC(c2cc3ccccc3s2)CC1 +CCCCc1nnc(OCc2ccccc2)n1Cc1ccc(NC(=O)c2ccccc2-c2nnn[nH]2)cc1 +CCCCn1c(=NC(=O)c2cc(C(F)(F)F)ccc2OCC(C)(C)O)sc2ncccc21 +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(C5CCN(CC(C)O)CC5)cc4)c3)c(OCCCF)cc21 +COc1ccc(C2c3nc(NC(C)C)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)c(O)c1 +COC(=O)C=Cc1cc(OC)c2c(c1)C(COC(=O)c1cc(O)c(O)c(O)c1)C(c1ccc(O)c(OC)c1)O2 +CONC(=O)c1ccc(C)c(Nc2ncnn3cc(NC(=O)OC(C)C)c(C)c23)c1 +O=C(Cc1cccc(Cl)c1)Nc1ccc(CCCCc2nnc(NC(=O)C(O)c3cccc(Cl)c3)s2)nn1 +CCCc1cc(Oc2ccccc2OCCn2ccc(=O)[nH]c2=O)c(C)c2cc(C#N)ccc12 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(C(O)c5ccccc5)C4)cc23)ccn1 +O=C(Cc1ccccc1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OCCO)c3)s2)nn1 +CCOc1ccc(-c2nc(NC(=O)C(N)COCc3ccccc3)sc2-c2cc(OC)c(OC)c(OC)c2)cc1 +Cc1ccc(-c2noc(C3CC(O)C3)n2)cc1NC(=O)c1cnc2ccc(F)cn12 +Cc1ccc(Oc2ccc(NC(=O)CNc3ccccc3N3CCCC3=O)cc2)cc1 +COC(=O)C1C2CCC3CCC1N(CC2=Cc1ccc(-c2cccs2)cc1)C3 +CN(C)C(=O)N1CC2CC(NCC(=O)N3CCCC3C#N)CC2C1 +CN(C)CCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4cccnc4)cc3)nc21 +CN1CCN(c2nccnc2Oc2ccc(Nc3ccccn3)cc2)CC1 +CC(C)C(CO)NCc1nc(-c2ccc(F)cn2)ccc1F +CCOCC(COCC)Oc1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +O=C(NCC#Cc1ccc2nccc(OCC3CCNC3)c2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +CCOc1ccc2nc(C)cc(N3CCN(C(=O)c4ccco4)CC3)c2c1 +CC(C(=O)N(C)C1CCCCC1)C1(O)CCN(CCc2ccccc2Cl)CC1 +N#Cc1ccc(C(c2cccnc2)N2CCC(NC(=O)c3ccccc3F)CC2)cc1 +CC(=O)Nc1cc(C(=O)NC(C)c2ccc(OC3CCN(c4ccnc(OC(C)C)c4)C3)cc2)ccn1 +O=C(O)CC(O)CC(O)CCn1c(C(F)(F)F)nc(-c2ccc(C(F)(F)F)cc2)c1-c1ccc(F)cc1 +CN1CCN(c2nc3ccccc3c(-c3ccccc3)c2CCOC2CCCO2)CC1 +O=C1Cc2c([nH]c3ccc(Br)cc23)-c2ccc(O)cc2N1 +Cc1ccc2ccccc2c1-c1cccc(COc2ccc3c(c2)OCC3CC(=O)O)c1 +CC1CCC2C(CNCCN)=C(C(F)(F)F)OC3OC4(C)CCC1C32OO4 +CC1CCNC(=O)c2cc3ccc(C(=O)Nc4cc(Cc5ccccc5)no4)nc3n21 +Cc1ncc([N+](=O)[O-])n1CCN1CCN(C(c2ccccc2)c2ccccc2)CC1 +CC1CN(c2ccc(F)cc2)CCN1c1nc(-c2ccncn2)cc(=O)n1C +N#Cc1ccc(Nc2nccc(C(=NO)c3ccccc3)n2)cc1 +CC(C)CN(CC(C)C)C(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +CN(C)C1Cc2ccccc2C(c2ccc(C(F)(F)F)cc2)C1 +O=C1C(N2CC(c3ccc(O)cc3)C2)CCN1Cc1ccc(F)cc1 +CCc1ncnc(-c2ccc(C(=O)N3CCn4c(C)cnc4C3)c(F)c2)c1C#Cc1ccc(N)nc1 +COc1cccc(NC(=O)Nc2nc(-c3cc4ccccc4o3)cs2)c1 +CC(Oc1cc(-n2cnc3cc(-c4ccncc4)ccc32)sc1C(N)=O)c1ccccc1Cl +CC(C)c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CC1CN(C(=O)N2Cc3c(C(=O)OC(C)(C)C)ncn3-c3cccc(Cl)c32)CC(C)N1 +CCC(c1nc2c(cnn2C(C)C)c(=O)[nH]1)N1CC(Oc2ccc(C)cc2)C1 +Cc1c(Nc2c(C#N)cncc2-c2ccc(OCCN3CCN(CCO)CC3)cc2)ccc2[nH]ccc12 +Cc1cc(=O)oc2c1ccc1sc(C(=O)c3ccccc3)c(-c3ccccc3)c12 +CCc1nc(-c2cc(-c3ccc(CO)cc3)c3c(N)ncnn23)cs1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c1ccc(C(=O)O)cc1 +O=C(O)c1ccc(NC(=O)C(Cc2ccccc2)CC(Cc2ccccc2)C(=O)O)cc1 +CC12CCC3C(C(Sc4cccc5ccccc45)CC4=CC(=O)CCC43C)C1CCC2=O +COCCCNC(=O)C(C)CC(O)C(N)CC(Cc1ccc(OC)c(OCCCOC)c1)C(C)C +O=C(NCC1CC(F)CN1)c1ccc(-c2cnc3ccc(NCCCCCF)nn23)cc1F +CCCNS(=O)(=O)Nc1ncnc(OCCOc2ncc(Br)cn2)c1-c1ccc(Br)cc1 +COc1ncc(-c2cc3c(C)nc(N)nc3n(C3CC(OCC(N)=O)C3)c2=O)cn1 +N#CCc1c(C(=O)Nc2cnc3ccccc3c2)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +CC(=O)NC(C)Cc1ccc(C#Cc2cnc(Oc3cccc(F)c3)nc2)cc1 +O=c1[nH]c(=NOCCCc2cccnc2)ccn1C1OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C1O +Cc1cccc(CNC(=O)C(=O)NC(C)C(=O)NC(CC(=O)O)C(=O)COc2c(F)c(F)cc(F)c2F)c1C +COC(=O)C(Nc1cc(CS(=O)(=O)C=Cc2c(OC)cc(OC)cc2OC)ccc1OC)c1ccc(Br)cc1 +COc1ccc(C(=O)NCc2ccc(OC)cc2C(F)(F)F)cc1 +Cc1cn(C2CC(O)C(CNC(=S)Nc3ccc(Cl)c(C(F)(F)F)c3)O2)c(=O)[nH]c1=O +COc1cc(-c2nncn2C)ccc1Nc1ncc2c(C)cnc(NCC(C)(C)C)c2n1 +Cc1cc(C)cc(NC(=O)c2sccc2SCc2ccncc2)c1 +CC(C)NC(=N)c1ccc(-c2cccc(-c3ccc(C(=N)NC(C)C)cc3)c2)cc1 +CCN(c1cc(-c2cnn(C)c2C)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +CC(C)(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2ccnc3c(Nc4ccc(C(F)(F)F)cc4)nsc23)c1 +CC(Nc1ncnc(N)c1C#Cc1ccc(F)cn1)c1nc2cccc(Cl)c2c(=O)n1N1CCNCC1 +Cn1cnc2cc(-c3ccc4c(c3)CC(=O)N4)nc(NC3CCOC3)c2c1=O +Cc1nc(C(=O)Nc2ccnc(Cl)c2)c(C)n1-c1ccc(F)cc1 +CN1CCN(c2nc3ccccc3c3c2CC2CCC3C2)CC1 +CN(C)CCn1cnc2c(c1=N)C(c1ccccc1)c1ccc3ccccc3c1O2 +NCCCCCCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +O=C(c1cn2ccn(Cc3ccc(Cl)c(Cl)c3)c(=O)c2n1)N1CCCCC1 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+CC(C)N1CCN(C(=O)N2Cc3c(NC(=O)c4ccccn4)n[nH]c3C2(C)C)C(C)C1 +O=C(c1ccc(Cl)cc1)C1CCN(c2ncnc3sccc23)CC1 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCCCCCC(=O)NO +CCN(CC)CCN1CCC2(C)c3cc(O)ccc3CC1C2C +O=C(NCC1CCN(c2ccncc2)CC1)c1ccc(I)c(OCCc2ccc(Cl)cc2Cl)c1 +O=C(Nc1n[nH]c2nc(-c3ccc(O)c(Br)c3)ccc12)C1CC1 +COCCOC(=O)N1CCC(C(NS(=O)(=O)c2ccc(-c3ccc(SC)cc3)cc2)C(=O)O)CC1 +NC(=O)c1cnc(-c2ccccc2)nc1Nc1ccc(CC(=O)NCC2CC2)cc1 +CC(Oc1ccc(N2CCC3(CCC(O)(CN4CCCC4=O)CC3)C2=O)cc1)C(F)(F)F +O=C1CCC(CCN2CC(N3CCOCC3)C2)(c2ccc(Cl)c(Cl)c2)CN1CC1CCCCC1 +Fc1ccc(C(OCCN2CC3CC(C2)N3Cc2cc3ccccc3o2)c2ccc(F)cc2)cc1 +O=C1N(CCCCCCCCO)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1CCCCCCCCO +CC(C)(C)Cc1ccc(-c2nc(-c3ccc(CN4CC(C(=O)O)C4)cc3)no2)cc1 +CCCCN1C(=O)C(CC2CCCCC2)NC(=O)C12CCN(Cc1ccc(Oc3ccc(F)cc3)cc1)CC2 +O=C1CCc2cc(-c3cncc(F)c3)cc3c2N1CC3 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1cc(F)cc(F)c1 +O=C(NC1CCCC1Nc1ncc(C(F)(F)F)cc1F)c1ncccc1-c1ncccn1 +C#Cc1cccc(Nc2ncnc3ccc(NC(=O)Nc4ccc(N(CCCl)CCCl)cc4)cc23)c1 +CS(=O)(=O)c1ccc(C2=C(c3ccc(CO)cc3)C(=O)OC2)cc1 +O=C1NC2(CCc3ccccc32)C(=O)N1CCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +COC(C)(C)CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C +COc1cccc(COc2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2C(F)(F)F)c1 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(Cl)ccnc12 +COCCCOc1cc(C(=O)N(CC2CNCC2OCc2cccc(-c3cccc(C)c3)c2)C(C)C)ccc1OC +COc1cc(CCCC=NN=C(N)N)cc(OS(=O)(=O)c2ccccc2Cl)c1 +CCOCC1CCC(COC2CCC(C(=O)O)CC2)N1C(=O)Cc1ccc2nc(Nc3ccccc3C)oc2c1F +NCCNc1cc(N2CCN(C(=O)C3(c4ccccc4)CCC3)CC2)nc2ccccc12 +CC(C)(C(N)C(=O)N1CC(F)CC1C#N)S(=O)(=O)Cc1ccc(F)cc1 +COC(=O)c1[nH]c2cccc(OC)c2c1C(=O)c1ccc(Cn2c(C)nc3cnccc32)cc1 +CCCCC(=O)Nc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1 +Cn1c(=O)[nH]c2cc(N3CCCC(C)(N)C3)n(Cc3ccccc3)c2c1=O +CCOC(=O)N1C(=S)N=C(C)C(=C(O)OCCN(C)Cc2ccccc2)C1c1ccccc1C(F)(F)F +Cc1ccn(CC(=O)N2CCN(C(=NC#N)Nc3ccccc3C)CC2c2ccccc2)n1 +NS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C=CC(=O)Nc2ccc(Cl)cc2)cc1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(NC3(C)CCCCC3)c2n1 +COc1cc(OC)c(S(=O)(=O)N2c3ccccc3CCC2C)cc1NC(=O)C=CC(=O)O +COC1CN(CCCc2cccc(NC(=O)C3CC3)c2)CCC1n1c(C)nc2cc(C)ccc21 +Cc1nn(C2CCCC2)c(C)c1S(=O)(=O)NC(C)CNc1cccc2c1cnn2-c1ccc(OC(F)(F)F)cc1 +CC(C)Nc1nc(-c2ccc3c(c2)S(=O)(=O)CC(=O)N3C)cc2ncn(C)c(=O)c12 +Cc1ccc(S(=O)(=O)N(C)c2ccccc2C(=O)c2ccsc2)cc1 +O=C(c1nnc(-c2ccccc2)o1)N1CC(Oc2ccc(CN3CC4(COC4)C3)cc2)C1 +CC1CN(c2ccc(F)c(NS(=O)(=O)c3ccc(-c4cccs4)cc3)c2)CC(C)N1 +CCc1[nH]cnc1CNc1cc(Cl)c2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1 +Cc1nc(-c2[nH]c(CNc3cccc(C(N)=O)c3)nc2-c2ccc3ncnn3c2)ccc1F +CC1(C)C(NC(=O)c2ccn(CCO)n2)C(C)(C)C1Oc1ccc(C#N)c(Cl)c1 +CC(C(=O)NCc1ccc(C(C)(C)C)cc1N1CCN(c2ccccc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +CN1C(=O)C(NC(=O)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)N=C(c2ccccc2)c2ccccc21 +COc1c(C(=N)N)cccc1-c1cc(-c2ccc(C(=N)N)cc2)no1 +COc1ccc(CCN2C(=S)NC3c4cccc(OC)c4OC2(C)C3C(=O)Nc2ccc(C)cc2C)cc1OC +COCc1cc(NC(=O)Cc2nc(N3CCOCC3)cc(=O)[nH]2)ccc1F +CC1(O)CCC2(C)C(CCC3C4CC=C(c5cccnc5)C4(C)CCC32)C1 +CC(C)C(CO)Nc1nc(Nc2ccc(-c3cccnc3)cc2)c2ncn(C(C)C)c2n1 +CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)nc(CN(C)C)cc21 +COC(C)(c1ccc(CN(c2ncc3ccccc3c2C)S(=O)(=O)c2ccc(C(=O)O)cc2)cc1F)C(F)(F)F +CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1ccc(C)cc1 +CC(C)c1ccccc1N1CCN(CCCCCC(=O)NCc2ccc(C#N)cc2)CC1 +CCC(C)C(=O)N1CCC(C(=O)NCc2ccc(OC)cc2C(F)(F)F)CC1 +COc1cc2c(cc1OC)C(=O)C(Cc1cc[n+](Cc3ccccc3)cc1)C2 +Cc1ccc(C(CCN(C)C)NC(=O)c2cccc(-c3ccc(Cl)cc3)c2)cc1 +O=S(=O)(O)CCNc1c(Br)cccc1Nc1ncnc2ccncc12 +CC(C)CN(C(CO)CCCCNC(=O)C(Cc1ccccc1Cl)NC(=O)c1ccncc1)S(=O)(=O)c1ccc(N)cc1 +Cc1ccc2[nH]c(-c3sc4nc(C)ccc4c3N)nc2c1 +OC1(CC2CCCN3CCCCC23)c2ccccc2Sc2ccccc21 +CCN(CC)C(=O)c1cc2c(s1)C(=O)c1c(O)cccc1C2=O +COc1cscc1C(=O)N1CCC(F)(CNCc2ccc(C)cn2)CC1 +O=C(O)c1cccc2c(=O)cc(-c3cccc(C=Cc4ccc5ccccc5n4)c3)oc12 +COc1ccc(N2CCN(CCCCc3c[nH]c4ccc(C(N)=O)cc34)CC2)c(OC)c1 +COc1ccccc1-c1ccc2cnc(Nc3cccc(N4CCOCC4)c3)nn12 +Cc1ccc(Oc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)cc1 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCCCCn1ccnc1[N+](=O)[O-] +COc1ccc(CC2CN3C(=NCC3C)N2CCC2CC3CCC2C3)cc1 +Cc1cccc(-c2nsc(SCC(=O)N3CCCC3)n2)c1 +CC1CCCN1CCCOc1ccc(-c2nn(C(C)C)c(=O)c3ccsc23)cc1 +CC1(CC(=O)O)CC(c2cccc(Cl)c2)C(c2ccc(Cl)cc2)N(C(CS(C)(=O)=O)C2CC2)C1=O +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(-n3cccn3)cc2)nc2ccc(Cl)cn12 +Cc1cc(CC(NC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)c2cccc(Br)n2)cc2cn[nH]c12 +O=C(O)CCC(NC(=O)c1ccc(CNc2ccc3ncnc(O)c3c2)cc1)C(=O)O +COc1cc2nccc(Oc3ccc4c(C(=O)NC5CC5)cccc4c3)c2cc1C(N)=O +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4cccc(F)c4)nc23)N1 +N#Cc1c(C2CCCNC2)cc(-c2c(O)cccc2OCC2CC2)nc1N +COc1cc(-c2ccc3ncc(C(C)=O)c(NC4CCC(CCN(C)C)CC4)c3c2)cc(Cl)c1O +O=C(NC1CCCN(c2nc(Cl)nc3cc(N4CCOCC4)ccc23)C1)c1cscn1 +CC(=O)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccc(F)cc21 +CCCCc1nc(Cl)c(C(=O)OC(C)OC(C)=O)n1Cc1cccc2c1ccn2-c1ccccc1-c1nn[nH]n1 +Cc1c(Cc2ccc(C(=O)O)cc2S(=O)(=O)c2ccccc2)c(-c2ccccc2)nn1CC(=O)O +CSc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2C1CCC1 +COC(=O)NC(C)CNc1nccc(-c2nc(C(C)(C)C)[nH]c2-c2cc(C)cc(NS(=O)(=O)C(C)C)c2)n1 +NC(=O)N1CCCc2cc(-c3cncc(OCCN4CCOC4=O)c3)cnc21 +O=C(c1ccc(Nc2ccc(Cl)cc2)nc1)N1CCCCCC1 +CCn1c(=O)c2cn[nH]c2c2ccc(-c3ccc(S(=O)(=O)N4CCOCC4)cc3)cc21 +Fc1ccc(C2(c3ccc(F)cc3)CNC(c3ccccc3)=N2)cc1 +CC(C)COc1cccc(C(C)Nc2nccc(N3C(=O)OCC3C(C)O)n2)c1 +CCCCc1nc(Cl)c(C(=O)O)n1Cc1ccc(NC(=O)C(Cc2cccs2)n2cccc2C(=O)O)cc1 +CC(C)=C1CC(CO)(COC(=O)COc2ccc(C#Cc3ccc(C)cc3)cc2)OC1=O +C=CC(=O)Nc1cccc(-n2c(=O)cnc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)c1 +CCn1cc(-c2cc3c(-c4cc(C(C)C)ccn4)n[nH]c3cn2)cn1 +Cc1cnc(Cl)c(-c2c[nH]c3ncnc(N4CCCC(C)C4)c23)c1 +CCCCC(CN(O)C=O)C(=O)NC(CC(C)C)C(=O)N(C)C +COc1cc(Nc2c(C#N)cnc3cc(-c4cccc(CN5CCOCC5)c4)c(OC)cc23)c(Cl)cc1Cl +CC(C)(C)c1cn(CC2CCCO2)c(=NC(=O)c2cc(C(F)(F)F)ccc2ON=C2CCCC2)s1 +CN(C)C1(CNCCc2ccccc2F)COc2ccccc2OC1 +CCCCN1CC(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(OCc3ccccc3)CN2)C(CC)C1=O +O=C1NC(=O)C(c2cnc3cccnn23)=C1c1cn2c3c(cccc13)CN(C(=O)N1CCCCC1)CC2 +COC(=O)CSc1nnc(Cc2csc(NCCC(=O)O)n2)n1NC(=O)c1ccc(Cl)cc1 +CCc1c(-c2nnc(C(C)(C)C)s2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Br)cc1 +NC1(c2ccc(-c3nc4c(Br)cc(Cl)cn4c3-c3ccccc3)cc2)CCC1 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+CCc1nc(Oc2cc(C)ccn2)c(CC)nc1NC(c1ccccc1)C(C)C +O=C(CCOc1cccnc1)Nc1ccc2nc3c4[nH]c5ccccc5c4ccn3c(=O)c2c1 +N#Cc1c(N)cc2c(c1N)Cc1cc3c(cc1O2)OCCO3 +COc1cccc(-c2c(C(=O)NN)[nH]c3ccc(S(N)(=O)=O)cc23)c1 +CSCCCNC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2C(N)CC(C)C)CC1 +O=c1ccc2cc(OCC(=NO)c3ccccc3)ccc2[nH]1 +Cc1ccnn1-c1ccc(C(=O)N2CCC(F)(F)C(=CC(=O)NCc3ccccn3)c3ccccc32)c(Cl)c1 +Cc1cc(C(C)Nc2ccccc2C(=O)NO)c2nc(N3CCOCC3)cc(=O)n2c1 +O=S(=O)(c1ccc(Cl)cc1)C1(c2cc(F)ccc2F)CCC(CI)CC1 +CN1CCN(CCC(=O)Nc2ccc(-c3cccc4c(=O)cc(N5CCOCC5)oc34)c3sc4ccccc4c23)CC1 +c1ccc(COCCCOc2ccc(C3C(CSc4ccncc4)CNCC3OCc3ccc4ccccc4c3)cc2)cc1 +CC(C)CCN1C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)C2CCCCC21 +COc1nc(NCCc2ccc(Cl)cc2Cl)cc(-c2cccc(C(C)(C)c3nnn[nH]3)c2)n1 +COc1ccc(-c2nc(CSc3cc(C)cc(C)c3)nc3ccsc23)cn1 +Cc1ccc(S(=O)(=O)NC(Cc2c[nH]c3ccccc23)C(=O)Nc2ccc(C(=O)NO)cc2)cc1 +CN1CCC(OC(=O)Nc2ccccc2-c2ccccc2)CC1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc4c(c3)NC(=O)CO4)nc2n1 +Cc1ccc(C(=O)C2CCN(CC(=O)NCc3nc4c(c(=O)[nH]3)COCC4)CC2)cc1 +CN1CCOCC1c1nc(C(=O)NCCc2ccccc2)c(O)c(=O)n1C +O=c1ccc(-c2ccc(Cl)cc2)cn1C(CN1CCCC1)c1ccccc1 +CN1CCC2(CC1)Oc1ccccc1C1CC(c3ccc(Cl)cc3)=NN12 +Cc1cc(O)ccc1-n1cnc2cc(O)cc(O)c2c1=O +CN(C)c1ccc(-c2cn(-c3ccc(I)cc3)nn2)cc1 +O=C1CCC(c2ccc3nc(-c4ccccc4)oc3c2)=NN1 +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CCc2nc(C(C)(C)C)ncc2C1 +Cn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(-c4cnn(C)c4)c2)CC3)cn1 +CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCS(=O)(=O)CC2)c1 +O=C(NC1c2ccccc2CC1O)C(Cc1ccccc1)CC(O)CN1C(=O)N(Cc2cccnc2)CC1Cc1ccccc1 +Cc1cccc(S(=O)(=O)NC(CNC(=O)Cc2cc(-c3ccc(C(=N)N)cc3)no2)C(=O)O)c1 +NCCCNC(=O)c1cccc(Nc2nccc(-c3cccnc3)n2)c1 +O=C(OCC1CCN(Cc2ccc(-c3ccccc3-c3nnn[nH]3)cc2)CC1)c1c2n(c3ccccc13)CCCO2 +Cc1cccc(NC(=O)CN2CCC(c3cccc(C#N)n3)CC2)c1 +Cc1n[nH]c(C)c1CC(=O)NCc1cccc(Cl)c1C +COc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(Cl)cc2C)N(C2CCC(O)CC2)C3=O)c(OC)n1 +COCc1nsc(N2CCN(C(=O)C3CNC(C(=O)N4CCCC4)C3)CC2)n1 +CC1(C)c2[nH]nc(NC(=O)c3cccs3)c2CN1C(=O)N1CCN2CCCC2C1 +Cc1ccc(-n2nccn2)c(C(=O)N2C(C)COC2Cn2cc(-c3ccc(F)cn3)cn2)c1 +CCN(CC)CCNc1n[n+]([O-])c2ccc(C(C)(C)C)cc2[n+]1[O-] +Cn1ncc(NC(=O)c2csc(-c3c(F)cc4c(c3F)OCC4)n2)c1C1CCC(N)C(F)CO1 +COc1cccc(Cl)c1-c1cc2[nH]c3ccc(O)cc3c2c2c1C(=O)NC2=O +CCc1nn(Cc2ccc(-c3nc4cc(F)ccc4[nH]3)cc2F)c(CC)c1CC(=O)O +CC(=O)C(C)N1CCC(NC(c2ccc(Cl)cc2)c2cccnc2)CC1 +CNS(=O)(=O)c1cccc(Nc2ncnc3[nH]cc(Cl)c23)c1 +S=C(NCCCn1ccnc1)Nc1ccc(OCc2ccccc2)cc1 +NS(=O)(=O)c1ccc(CCn2c(=S)[nH]c3ccccc3c2=O)cc1 +COC(=O)Nc1n[nH]c2cc(NC(=O)NC(C)c3ccc(F)cc3)ncc12 +COc1ccc(-c2sc3ccccc3c2C(=O)c2ccc(OCCN3CCCCC3)cc2)cc1 +C=CC(=O)N1CCC(Oc2cc3c(Nc4cccc(C=C)c4)ncnc3cc2OC)CC1 +COc1cccc(OC(C)c2cc(C(=O)N(C)CCO)cn3c(=O)cc(N4CCOCC4)nc23)c1 +COc1ccc(C(=O)Nc2ccc(F)c(C3(C(F)F)N=C(N)OC4CC43)c2)nc1 +Cn1nc(CC(=O)Nc2cccc(-c3ccc(C#N)cc3)c2)c2ccccc2c1=O +COc1cccc(-c2cnc3c(NCc4ccc(S(N)(=O)=O)cc4)nccn23)c1 +CSC1COCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +NS(=O)(=O)Nc1ccc(-c2ccc(C(F)(F)F)cn2)cc1 +Cc1nc2cnccc2n1-c1ccc(C(=O)NCc2cccc(C(=O)Nc3ccc4c(c3)CN(C)CC4)c2)cc1 +Cc1cc(COc2ccc(NC(=O)C3CN(C)CCC3C(=O)NO)cc2)c2ccccc2n1 +CCCCc1ccc(OCCC(NC(C)C(=O)O)C(=O)N2NCCCC2C(=O)NC)cc1 +CCCCn1cnc2c(NCc3ccc(C)cc3)nc(C#N)nc21 +CCCCC(c1ccc(C(F)(F)F)nc1)N1CCC(CC(=O)O)CC1c1ccc(C(F)(F)F)cc1 +COc1ccc(C(C#N)(CCCN2CCc3cc(OC)c(OC)cc3C2)Sc2ccc(C)cc2)cc1OC +Cc1ccc(C(=O)C=Cc2ccc(O)c(O)c2)c(C)c1 +CN(CCCc1ccc(C(F)(F)F)cc1)c1nc(NCCc2ccc(O)cc2)nc(N2CCNCC2)n1 +Cc1cccc2cc(Cn3nc(I)c4c(N)ncnc43)n(-c3ccccc3O)c(=O)c12 +COc1ccc(C(C(=O)NC(C)(C)C)N2C(=O)C(C3Cc4ccccc4C3)NC(=O)C2CC(C)C)cc1 +COc1ccc(S(=O)(=O)N(CC(=O)NCC2CCCCC2)C(CCSCc2ccccc2)C(=O)NO)cc1 +CCN(CC)CCN1C(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +COc1cc2nc(S)n(CCc3ccc(S(N)(=O)=O)cc3)c(=O)c2cc1OC +COC12CCC3(CC1C(C)(O)c1cccs1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+]1(C)CCCCC1 +COc1ccncc1-c1ncccc1CN(C(=O)c1ccc(-c2ccc(C#N)cc2)o1)c1ccc(N2CCNCC2)cc1 +CCNC(=O)C1OC(n2cnc3c(N)nc(C#Cc4ccc(CCC(=O)OC(C)(C)C)cc4)nc32)C(O)C1O +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(c2ccccc2)C1 +CC(C)=CCn1c(N2CCCC(N)C2)nc2c1c(=O)n(CC(=O)N1CCCCC1)c(=O)n2C +CCCCN=C(N)c1ccc(C(=O)NC(CC)C(C)(C)C(=O)N2CCC(CC(=O)O)CC2)c(F)c1 +Cc1occc1C(S)=Nc1ccc(Cl)c(CNOC(C)(C)C)c1 +O=C(CN(CCNc1ccnc2cc(Cl)ccc12)C(=O)c1cnccn1)NC1CCCCC1 +COC(=O)N1CCC(OC)(c2nc(C)c(-c3cc(C(=O)N4CC(c5ccc(C#N)cc5)C4)ccc3C)[nH]2)CC1 +COc1ccc(C2C(c3ccc(O)cc3)C(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1O +Fc1cccc(C2CCN(CCCNc3nc4ccccc4n3-c3ccc(Cl)cc3)CC2)c1 +O=C1C2Cc3c([nH]c4ccccc34)C(c3ccc4c(c3)OCO4)N2C(=O)CN1C1CCN(CCc2ncc[nH]2)C1 +CCOC(=O)c1cnc(N2CCN(C(=O)NS(=O)(=O)c3ccccc3C)CC2)c(Cl)c1 +COc1ccc(CN(C)C2(c3ccccc3)CCC(c3ccccc3)(N(C)C)CC2)cc1 +Nc1nc(OC(c2ccc(Cl)cc2-c2ccc(Cl)cc2)C(F)(F)F)cc(N2CCC3(CC2)CNC(C(=O)O)C3)n1 +Clc1ccc(CN2CCC(c3cc(-c4ccc(Cl)cc4)on3)CC2)cc1 +NC1CN(c2ccc3nnc(-c4ccc(F)cc4)n3n2)CCC1c1cc(F)c(F)cc1F +COCC1CC2CCC(C1)N2c1nc(N2CCC(C(N)=O)C2)nc2scc(-c3ccccc3OC)c12 +COc1cccc(C2CN3CCCC3c3cc(OCCCN4CCCCC4)ccc32)c1 +CCC1CC(O)=C(C2=Nc3ccc(NS(C)(=O)=O)cc3S(=O)(=O)N2)C(=O)N1Cc1ccc(F)cc1 +CC1CC2(C)CC(=O)C1C1C(=O)N(OCCCN3CCN(c4ccccc4)CC3)C(=O)C12 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+O=C(NCC1CCNCC1)c1c(F)cccc1-c1cccc(Cl)c1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccc(N(C)C)cc1 +Cc1cccc(S(=O)(=O)c2c(C(N)=O)[nH]c3ccc(Cl)cc23)c1 +COc1ccc(OC2OC(CO)C(OC3OC(CO)C(O)C(O)C3O)C(O)C2O)cc1 +CC1(C)Cc2c(c(N3CCOCC3)nc3sc4c(NCc5cccnc5)ncnc4c23)CO1 +NC(=O)C(Nc1ccccc1[N+](=O)[O-])c1c(Cl)cccc1Cl +Cc1nc2ccccn2c1-c1ccnc(Nc2ccc(Cl)cc2)n1 +CCOc1ccc(-n2c(C)c3c(C)nnc(CCC(C)C)c3c2C)cc1 +CN(CCCN(C)CCCC(O)(c1ccccc1)c1ccccc1)CCCC(O)(c1ccccc1)c1ccccc1 +Cc1ccccc1COc1ccc(S(=O)(=O)N2CCN(Cc3ccccc3)C(C)C2C(=O)NO)cc1 +Cc1cnccc1-c1nc(C)c2c(C)nc3c(F)cc(OC(F)F)cc3n12 +O=C(NC(c1ccc(Cl)cc1)c1cnccn1)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1 +COc1ccc2c(c1)C1(CC1c1ccc3c(C=Cc4ccc(CN5CCOCC5)cc4)n[nH]c3c1)C(=O)N2C +CN1CC=CCCOc2cccc(c2)-c2ccnc(n2)Nc2ccc(OCCN3CCCCC3)c(c2)C1 +O=S(=O)(c1cccc(-c2ccccc2)n1)N1CCCCC1c1nnn[nH]1 +O=C1COc2ccc(CNC3CCN(CCn4c(=O)ccc5ncc(Oc6cccnc6)cc54)CC3F)nc2N1 +O=c1oc2cc(S(=O)(=O)Nc3ncns3)ccc2n1Cc1ccccc1 +Nc1cc(-c2ccccc2)nc2c1cnn2Cc1ccncc1 +c1ccc(CCNc2ccc3nnc(-c4ccccc4)n3n2)cc1 +CCCCCC(O)C=CC1C2CC(OO2)C1CC=CCCCC(=O)O +COc1ccc(-c2ccc(CCNC(=O)c3ccc4c(c3)C3(C)CCN(CC5CC5)C(C4)C3C)cc2)cc1OC +COc1ccc(-c2cc(=O)c3cc(OC)c(OC)c(OC)c3o2)cc1O +Cc1nc(Nc2cc(C#N)ccn2)cc(C2CCCN(C(=O)c3ccccc3)C2)n1 +N#Cc1cc(COc2ccc3[nH]c4c(c3c2)CCNC4CC(=O)O)cc(OC(F)(F)F)c1 +Cc1cnnc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)n1 +Cc1cccc(NC(=O)CN2CCC(c3cccc(F)c3)CC2)c1 +Oc1cc(CCCc2ccccc2)ccc1Oc1ccc(Cl)cc1Cl +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C(O)C(I)I +O=C(CCCCCCC(=NO)c1ccc(-c2ccccc2)cc1)NO +COc1cc2cc(CO)c(CO)c(C3=CCN(C)C(=O)C3)c2cc1OC +Cc1ccccc1-c1nc2cc(-c3nc4cc(N5CCN(C)CC5)ccc4[nH]3)ccc2[nH]1 +CCOc1cc(CN2CCC3(CC2)CN(c2ccc(C(=O)O)cn2)C(=O)O3)cc(OCC)c1-c1ccc(F)cc1 +Nc1ncnn2c(CN3CCCC(O)C3)cc(-c3cc(F)c(CO)c(F)c3)c12 +N#Cc1cnc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)cc1OC1CN2CCC1CC2 +O=C(c1cc2n(n1)CCN(Cc1cccc(Cl)c1)C2=O)N1CCCCC1 +COc1cc2c(cc1OC)C1CC(N)C(c3ccccc3)CN1CC2 +Cc1nn2ncccc2c1-c1ccnc(Nc2ccc(N3CCN(C)CC3)cc2)n1 +N#Cc1nccc(N2CCC(S(=O)(=O)c3cccc(Cl)c3Cl)C2)n1 +CS(=O)(=O)c1cc(C#N)ccc1C1NC(=O)N(c2cncc(Br)c2)C2=C1C(=O)CC2 +CCN(CC)C(=O)COc1cccc(C(C)Nc2cc(-c3ccc4ncsc4c3)nc(C)n2)c1 +O=C(NC1CCC1)c1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +CCc1cc(Nc2cc(=O)n(CCCCCO)c(=O)[nH]2)ccc1C +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CCCCC3C)c2)[nH]1 +NC1CCC(Nc2nccn3c(-c4cccc(NCc5ccsc5)n4)cnc23)CC1 +O=C1CC(C(=O)Nc2cc(-c3cc(F)cc(COCC(F)(F)F)c3)n(-c3ccccc3Cl)n2)CN1 +C=CC(=O)Nc1ccc2ncnc(Cc3ccc(CN(C)C)c(Br)c3)c2c1 +CC(NC(=O)Nc1cc2[nH]nc(C3CCC3)c2cn1)c1ccccn1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)c(=O)n(C)n2C)n1)c1ccccc1 +Cc1nnn(-c2ccc(-c3ccc(C4(C(=O)O)CC4)cc3)cc2)c1NC(=O)OC(C)c1ccccc1 +CCCCS(=O)(=O)N1CC(NC(=O)c2ccc(Cc3cc(C)nc4ccccc34)cc2)C(C(=O)NO)C1 +Cn1c2c(c3ccccc31)CCN(CCCOc1ccccc1)C2 +O=C(CCc1ccccc1)c1ccccc1OCCCCN1CCCCC1 +CC(=O)OC(OC(C)=O)c1ccc2c(c1)COP(=O)(OCC1C=CC(n3cc(C)c(=O)[nH]c3=O)O1)O2 +COc1ccc(C(Cc2ccccc2)NCC(O)Cc2ccc(O)c(NS(C)(=O)=O)c2)cc1O +Cc1cc(C)cc(-c2[nH]c3ccccc3c2CCNCCCCc2cccnc2)c1 +CC(O)c1cccc(-c2cc(OC(=O)NC3CCCCC3)ccc2O)c1 +Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(N)c5)cc(C(F)(F)F)nc34)cn2)cn1 +O=C(Oc1cccc(-c2ccccc2)c1)N1CCc2c([nH]c3ccccc23)C1 +O=C(Nc1ccccc1)OCCc1cc(-c2cncc(OCC3CCN3)c2)on1 +CCN(C)Cc1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +O=C(Nc1ccc(C(F)(F)F)cn1)N1CCC(F)(c2ncc(C(O)CO)cc2F)CC1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)c2cncc(F)c21 +O=C1OC2(CCN(CCc3c[nH]c4ccc(F)cc34)CC2)CN1Cc1ccccn1 +CNC(=O)C(NC(=O)c1ccc(-c2cccc(CNC(=O)c3ccnc(C(F)(F)F)n3)c2)o1)C(C)C +CCCCS(=O)(=O)Nc1ccc(C(=O)NC(CC2(C)CCCC2)C(=O)NC2C(=O)COC2CC)cc1 +CS(=O)(=O)N1CCN(c2ccnc(Nc3ncc(-c4cncc(C(=O)NCCN)c4)s3)c2)CC1 +CCCCCCN(C(=O)Nc1ccccc1OC)C(C)c1nc2ccccc2c(=O)n1-c1ccccc1OCC +COc1cc(NC(=S)NCCCn2cncc2C)ccc1OCCCCc1ccnc(N)c1 +Nc1ncnc2c1c1ccsc1n2C1OC(CO)C(O)C1O +CCCOc1cncc(C2=CCC3C4CCN5C(=O)CCCCC5(C)C4CCC23C)c1 +CC(C)CC(=O)C1C(=O)C(=O)N(c2ccc(-c3ccsc3)cc2)C1c1ccccc1OC(F)F +O=C(NCC(O)C(=O)O)c1ccc(CN(C(=O)Nc2cccc(Cl)c2)c2ccc(C3=CCCCC3)cc2)cc1 +CCN1CCN(Cc2ccc(NC(=O)c3ccc(-c4cc(C)cc(OC)c4C)c4nccnc34)nc2)CC1 +CCN(Cc1ccncc1)C(=O)C(C)N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O +O=C(CO)Nc1cncc(-c2cncc(Nc3cccc(Cl)c3)n2)c1 +N=C(NCCCc1c[nH]cn1)NCCC(Cc1ccccc1)c1ccc(F)cc1 +COc1cccc(N2CCN(CCNCCOc3ccccc3)C(Cc3ccccc3)C2)c1 +N#Cc1c(-c2ccccc2)c2ccccc2n(CC2CCCNC2)c1=O +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1cccc(Cc2ccoc2)c1 +C=CCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +CNS(=O)(=O)Cc1ccc2[nH]cc(CC3CCCN3C)c2c1 +O=C(Oc1ccc(Oc2nccc(-c3c(-c4ccc(F)cc4)ncn3C3CCNCC3)n2)cc1)c1ccccc1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3ccc(-c4ccccc4)cc3)ccc21 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCCC3)n2)cc1OC(F)F +O=S(=O)(Oc1ccc(Cn2ccnc2)cc1)c1ccc(C(F)(F)F)cc1 +O=C1C2C=CC(C3C2C=CC(=O)C32CO2)C12CO2 +OC(CCN1CCN(c2cccc3cccnc23)CC1)c1csc2ccccc12 +CC(=O)Nc1ccc(Nc2cc(C(C)C)nc3c(-c4ccccc4)c(C)nn23)cc1 +Cc1nnsc1C1=NNC(=O)C1=Cc1cn(C)c2cccc(Cl)c12 +CCOc1ccc2c(c1)C(c1ccc(OC)cc1OCC(C)(C)C(=O)O)N(CC(=O)O)C2c1ccc2c(c1)OCO2 +Cc1cccc(F)c1CN1CC(c2ccc(-c3cnn(CC(N)=O)c3)cc2)C(N(C)C)C1 +CCOC(=O)c1ccc(Nc2nc(-c3ccncc3)nc3ccccc23)cc1 +Fc1ccc(C2COC(c3ccc(C4CNCCO4)cc3)=N2)cc1 +CCC(=CCN1Cc2cc(Cl)cc3nc(S)n(c23)CC1C)CC +COc1ccc(C(=O)NCc2cccc(-c3cccc(CN4CCNCC4)c3)c2)cc1 +Cc1ccc(C(=O)NC2COC2)c(F)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)c3cccc(OC)c3)nc21 +CC1CCC(C)N1C(=O)c1ccncc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1 +Cn1ccc(C2CCNCC2C(=O)N(Cc2cn(Cc3ccncc3)c3cccc(F)c23)C2CC2)cc1=O +Cn1cccc1C(=O)N1CCc2ccc(C(=O)NO)cc2CC1 +O=C(Oc1ccccc1)N1CCN(C2c3ccc(Cl)cc3C=Cc3cccnc32)CC1 +COc1ccc2cc(C(=O)NC(CC(C)C)C(=O)NC(CC3CCNC3=O)C(=O)c3nc4ccccc4s3)[nH]c2c1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3Cl)CC2)cc1 +C=CC(=O)NC1C(NCC(C)C)CC(C(=O)O)=CC1OC(CC)CC +O=C(O)CC1CCC(c2ccc(NC(=O)c3nnc(Nc4ccc(F)c(F)c4)o3)cc2)CC1 +CN(CCCCCN1C(=O)CSC1c1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)CCOc1ccc2c(c1)OCO2 +CN(C)CCCCCNc1cc2ncnc(Nc3cccc(Br)c3)c2cn1 +N#CC1CCCC1Nc1nc(-c2ccccc2)nc2c(=O)[nH]ccc12 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccc(F)cc1)CC2 +COc1cc(O)c(C(=O)OC(C)C)c(CCCN2C(=O)C=CC2=O)c1 +Cc1cc(CCNCc2ccc3c(C)cc(N)nc3c2)ccc1C#N 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+NS(=O)(=O)c1ccc(-c2[nH]c3ccccc3c2-c2ccc(F)cc2)cc1 +O=[N+]([O-])c1ncn(CCCCNc2nc(-c3ccccc3)nc3ccccc23)n1 +N#CC1(NC(=O)C2Cc3ccc(c(Cl)c3)OCC=CCNc3ccccc3C(=O)N2)CC1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2cccs2)[nH]c1=O +O=C1OCc2cc(CCN3CCN(C(=O)Cc4ccc(-n5cnnn5)nc4)CC3)ccc21 +CCOC(=O)c1c(C)n(-c2ccc(Cl)cc2)c2ccc(OC(=O)C=Cc3ccccc3)cc12 +CC#CCN(Cc1ccc2nc(N)nc(O)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +COC(=O)C(C)NC(=O)CCC(C)=CCc1c(O)c2c(c(C)c1OC)COC2=O +CN1CCCC(n2c(-c3cccc(C=CC(=O)NO)c3)nc3ccccc32)C1 +COc1ccc2c(c1)C(CC(=O)N1CCN(C(=O)c3ccccc3N3CCC(=O)NC3=O)CC1)CC2=O +OCC1OC(Oc2n[nH]c(C3CC3)c2Cc2ccccc2OCc2ccccc2)C(O)C(O)C1O +CCN(c1cc(-c2ccn(C)n2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +COc1cc2c(cc1OC)C(Cc1ccc(OCCCCCCN3CCCCC3C)cc1)NCC2 +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CN(c4ncc(C(=O)O)cn4)C5)cn3)n2)s1 +CN(C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)C1CCN(C(=O)N2CCC(NCCCC3CCCCC3)C2)C1 +O=C(NCc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1cc2cnccc2[nH]1 +O=C(COc1ccccc1)NC(c1ccccc1Cl)c1cc(Br)c2cccnc2c1O +O=C1NCC(=O)N(Cc2ccco2)C1CSCc1ccccc1 +CCC(=O)c1ccc(F)c(C2CC2NC(=O)Nc2ccc(C#N)cn2)c1O +Cc1ccc(C23CC4CC(CC(C(=O)N5CCN(CCO)CC5)(C4)C2)C3)cc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C +O=C1COc2ccc(CCN3CCN(c4cccc5nc(-c6ccccc6)ccc45)CC3)cc2N1 +COc1cc(Cc2cnc(N)nc2N)cc(CC(C)O)c1O +CC1CCCN1CCc1ccc(-c2cccc(S(=O)(=O)N3CCCCC3)c2)cc1 +Oc1ccccc1CNCCCCCCNc1c2c(nc3ccccc13)CCCC2 +N#CC1(c2ccccc2)CCN(Cc2cccc3ccccc23)CC1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ccc(C(F)F)cn3)cs2)CO1 +CC(C)C(Nc1cccc(C(F)(F)F)c1)C(=O)N1CCCCN1C#N +COc1ccc(C(NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)Nc2ccc3c(c2)OCO3)cc1 +O=C(c1cc(-c2cccs2)n[nH]1)N1N=C(c2cccnc2)CC1c1ccccc1O +CN(C)c1nc(N2CC3CN(C(=O)c4c(F)cccc4-n4nccn4)CC3C2)cc(C(F)(F)F)n1 +CCOc1ccc2c(c1)C1(C)CCN(CC3CC3)C(C2=O)C1C +Cc1cc(-c2nc3ccccc3[nH]2)nn1Cc1cc(Cl)cc2cc(C(C)C)oc12 +CC12CCN(C(=O)C3CCC(F)(F)CC3)C(Cc3c(O)cccc31)C2(C)C +N=C(N)NCCC1CCN(C(=O)C(Cc2cccc(C(=N)N)c2)NS(=O)(=O)c2ccc(Oc3ccccc3)cc2)CC1 +O=c1[nH]c2cc(-c3ccncn3)c(-c3ccco3)nc2[nH]1 +CN1CCN2c3c(cccc31)C1CN(CCCC(=O)c3ccccc3)CCC12 +COc1ccccc1C=Cc1nc2c(c(=O)n(C)c(=O)n2C)n1C +CC1(N2CCC(N(c3ccccc3)c3ccccc3)CC2)CCN(C(=O)c2ccccc2)CC1 +O=C(O)CCNC(=O)c1ccc(-c2cc(Cl)ccc2C(=O)Nc2ccc(-c3ccc(Cl)cc3)cc2)cn1 +O=C(Nc1ccc(N2CCOCC2)cn1)C1CCC2CN1C(=O)N2OS(=O)(=O)O +COc1cc(C(=O)NCC2(c3ccc(F)cc3)CCC2)ccc1-n1cnc(C)c1 +CC(C)(C)c1cc2cc(NC(=O)C3(c4ccc5c(c4)OCO5)CC3)c(F)cc2n1CC(O)CO +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CC(c4cc(C(F)(F)F)cc(Cl)c4F)=NO2)C3=O)cn1 +CCCCOC(C#CC1CC1)(c1cc(CC)c(C)nc1O)C(F)(F)F +O=C(NC(=S)Nc1ccc(S(=O)(=O)N(Cc2ccncc2)c2ccccc2)cc1)c1ccc2cccnc2c1 +CC(=O)N1CCN(c2cccc(-c3cc(C#N)c4c(N)ncnn34)c2)C(=O)C1(C)C +O=C(Nc1ccc(F)cc1)C(=O)Nc1ccc2c(c1)COC2=O +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)OC(C)C)ncc2c1 +NC(=O)NCCn1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21 +COc1ccn2c(C(=O)c3cc(OC)c(OC)c(OC)c3)cnc2c1 +O=C(c1cccc2ccccc12)N1Cc2ccccc2N(Cc2c[nH]cn2)CC1Cc1ccccc1 +CN(C)CCCN(C(=O)c1cccs1)c1nc2cc3c(cc2s1)OCO3 +O=C(c1cccc(-n2cccn2)c1)N1CCC(F)(F)C(Oc2ccc3ccccc3n2)C1 +FC(F)(F)c1cccc(Nc2n[nH]c3cccnc23)c1 +CS(=O)(=O)Nc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)C=Cc4ccc(Cl)c(Cl)c4)CC3)c2c1 +CCOc1ccc(-c2cccc(NS(C)(=O)=O)c2)cc1-c1ccc2c(N)nc(N)nc2c1 +O=C(O)COc1ccc(C(F)(F)F)cc1-c1ccccc1 +Cc1cccc2c(=O)[nH]c(CCN3CCCC3CO)cc12 +O=c1[nH]c2cc(Cl)c(-n3cccc3)cc2c(=O)n1O +Cc1cc2ccn(C)c2c2c3c(c4c5ccccc5n(CCCO)c4c12)C(=O)NC3=O +O=S(=O)(Nc1ccc(CCNCC(O)c2ccccc2)cc1)c1ccc(Cc2nc(-c3ccc4ncccc4c3)cs2)cc1 +O=C(Nc1cc2ccc(Sc3ccccc3)cc2cn1)C1CC1 +Cc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C2CCOCC2)n1 +NS(=O)(=O)OCC1OC(n2cnc3c(C#Cc4ccccc4)ncnc32)C(O)C1O +CCCCn1c(=O)c(NC(=O)Nc2c(C(C)C)cccc2C(C)C)c(-c2cccc(OC)c2)c2cccnc21 +COc1ccccc1-c1sc(N)nc1-c1ccc(P(=O)(O)O)o1 +O=C(O)COc1cc(CC2CCN(CCc3ccc4c(c3)C(=O)C(O)CO4)CC2)ccc1Br +O=C(C1CN(Cc2ccccc2)CC1c1ccc(Cl)cc1)N1CCN(C2(CNCc3ccccc3)CCCCC2)CC1 +CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc(Cl)cc3)ccc21 +COc1cc2ncnc(Oc3ccc(NC(=O)Nc4cc(C)on4)c4ccccc34)c2cc1OC +NC1=NC(CCc2ccc(NC(c3ccc(Br)cn3)C(F)(F)F)cc2)CO1 +Cc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C(O)C(C)C)n1 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+CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)cc(-c3ccc(F)cc3)c2C)cc1 +O=C(c1ccc(-c2cn3c4nc(ncc24)NCCCCCCCC(O)CCCC3)cc1)N1CCOCC1 +N=C(N)NCCCCCCCCCNc1c2c(nc3ccccc13)CCCC2 +CC(C)(C)c1cc(NC(=O)C(=O)c2cccc3ccccc23)n(-c2ccc(OCCC(N)=O)cc2)n1 +COC1CN(c2nc(-c3cc(C)ccc3OCc3ccc4c(c3C)CCN(C3CCOCC3)C4=O)cs2)CCC1C(=O)O +CCc1oc2ccccc2c1C1CCN(CCc2ccccc2)CC1 +Cc1csc[n+]1CCCCCCCCCCCC[n+]1cscc1C +Cn1ncc2cc3c(cc21)ncc1c(=O)n(-c2ccc(Cl)cc2)[nH]c13 +CCCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)c(F)c2)cc2cc(F)ccc21 +Nc1nc(-c2ccccc2)c2c(n1)-c1cc(CNN3CCCCC3)ccc1C2=O +Cn1cc(-c2ccccc2)nc1SCc1cn2c(C(F)(F)F)cccc2n1 +COc1cc(N2CCN(C)CC2)ccc1Nc1nc(N)n(C(=O)NCc2ccccc2S(=O)(=O)C(C)C)n1 +Nc1ccc(NCCc2ccc(OCCCN3CCCCC3)cc2)nc1 +Nc1ncc2cccc(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2n1 +O=C(c1ccccc1)N1CC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)C1 +CC1C(=O)N(Cc2ccc(F)c(F)c2)c2c(C=CC(=O)NS(=O)(=O)c3cccc(Cl)c3)cccc21 +NS(=O)(=O)c1ccc(C(=O)NC(C(=O)NCC(=O)NCC(=O)OCc2ccccc2)c2ccccc2)cc1 +Cc1cc(Nc2nc(Sc3ccc(Cl)c(Cl)c3)nc3ccccc23)n[nH]1 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+Nc1ncnc2c1c(-c1ccc(Oc3ccccc3)cc1)nn2C1CCC(NC(=O)C=CCN2CCOCC2)CC1 +COc1cc(N(CC2CC2)c2ccc3c4c(cccc24)CC3)cnc1C(=O)C1CC1C(=O)O +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)cc1OCCCNCC(O)c1ccc(O)c(CO)c1 +Nc1ncnc2c1ncn2C1OC(CSC2CNC(C(=O)O)C2)C(O)C1O +O=C(NCc1cn(-c2ccc(F)cc2)nn1)C(Cc1cscn1)NC(=O)C1OC1C(=O)O +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NCCCN(C)C +COCc1c(-c2cc3cc(OC)cc(OC)c3s2)c2c(N)ncnn2c1CN1CCNC(=O)C1 +O=C1C(NCCN2CCCC2)=CC2=NCCc3c[nH]c1c32 +COc1ccc(-c2n[se]nc2-c2ccc3c(c2)OCO3)cc1O +CC(C)(C)c1ccc(-n2c(C(=O)O)c(Oc3cccc(C(F)(F)F)c3)c3ccccc32)cc1 +CC(C)(NC(=O)c1nn(-c2ccc(F)cc2F)c2c1CC1CC21)c1cccnc1 +Cn1cnc2cc(-c3ccc4c(c3)CC(=O)N4)nc(N3CCC(CO)C3)c2c1=O +Oc1ccc2c(c1)C1(CCc3ccccc3)CCN(CCc3ccc(C(F)(F)F)cc3)CC1O2 +Cn1cc(-c2ccc(N3CCC(n4ncc5ccc(C(F)(F)F)cc54)CC3)nn2)cn1 +N#Cc1cccc(C(=O)Nc2ccc(CC(NC(=O)C3CCC(=O)N3Cc3ccccc3)C(=O)O)cc2)c1 +Cn1nc(C(C)(C)C)c(Cl)c1-c1nc2cc(-c3ccccc3C(F)(F)F)nc(N3CCOCC3)c2[nH]1 +N#Cc1cccc(-c2ccc(C3(OCC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)CCN(C4CCCC4)CC3)cc2)c1 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+O=C(NNc1cccc2ncccc12)C1(c2cccc(F)c2)CCCCC1 +COc1cc2c(cc1OC)C1C3Cc4cc(OC)c(OC)cc4C(COC(=O)c4cccs4)N3C(C#N)C(C2)N1C +Cc1ncc(C)c(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)n1 +COc1cccc(N2CCN(CCCN3C(=O)CCc4c(Cl)cccc43)CC2)c1 +COc1cc2ncnc(N3CCC(Oc4cc5ccccc5cn4)C3)c2cc1OC +CSCCC(NC(=O)c1cccc(CN(Cc2ccccc2)Cc2c[nH]cn2)c1)C(=O)O +CCS(=O)(=O)CCc1ccc(-c2nnc(-c3ccccc3C(F)(F)F)n2C)c(C)c1 +CC(NC(=O)C(O)C(N)CCc1ccccc1)c1cccc2ccccc12 +CCN(CC)CCCNc1nccc2c(C)c3[nH]c4ncccc4c3cc12 +CC1OC(=O)C2CC3CCCCC3C(C=Cc3ccc4cc(-c5cccc(C(F)(F)F)c5)ccc4n3)C12 +Oc1ccc(-c2cncc(-c3cc4ccc(O)cc4[nH]3)c2)cc1 +COC(=O)Nc1nc2ccc(Oc3ccc(NC(=O)Nc4cc(C(F)(F)F)ccc4F)cc3)cc2s1 +CC(C)CC(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)C(=O)N(C)C +N#CC1CCCN(c2cccnc2Oc2ccc(Nc3ccccn3)cc2)C1 +O=C(O)c1ccc(Cl)cc1-c1ccc2c(c1)OCC(Cc1ccc(C(F)(F)F)cc1)C2O +CN1C(=O)c2c(nn(Cc3ccc(-c4cc(F)ccn4)cc3)c2Nc2ccccc2)N2C1=NC1CCCC12 +Fc1ccc(-c2[nH]c(-c3ccc(Br)cc3)nc2-c2ccncc2)cc1 +COc1ccc(N2CCC(NC(c3cccnc3)c3ccc(Cl)cc3F)CC2)cc1F +N=C(N)N1CCCC(CNC(=O)CNS(=O)(=O)c2ccc3ccccc3c2)C1 +O=C(Nc1ccccc1-c1cn2c(CN3CCNCC3)csc2n1)c1cc2ccccc2o1 +O=C(NCCNCCO)c1cccc2ccc(-c3ccccc3)nc12 +CC1(c2cccc(O)c2)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O +CC(C(O)c1ccccc1)N(C)C(S)=Nc1ccc(Oc2ccccc2)cc1 +COC(=O)c1ccc(SCc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 +O=C(CCN1CCC(n2ccnc2)CC1)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1 +CCC(C)C1(NC(C)=O)CCN(C(C)C(=O)NC(Cc2cc(F)cc(F)c2)C(O)C2CC(O)CN2)C1=O +O=C(NO)c1ccccc1S(=O)(=O)N1CCC(Cc2ccccc2)CC1 +CN(c1ncccc1CNc1c(C(F)(F)F)cnc2[nH]c(-c3ccc(F)cc3)nc12)S(C)(=O)=O +Cn1c(=O)n(C2COC2)c2c3cc(-c4ccc(OCCCN5CCCCC5)nc4)ccc3ncc21 +c1ccc(C2CCc3cc(Oc4ncc(CNCC5CC5)s4)ccc3O2)cc1 +CC(C)(CO)n1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +CN(C)C(=O)c1cccc(N=c2c(O)c(O)c2=Nc2ccccc2)c1O +O=C(Nc1nc(CN2CCC(C(=O)NC3CCCC3)CC2)cs1)c1ccc(Cl)cc1 +O=C(Nc1nnc(SCc2ccccc2)s1)c1ccc(Cl)cc1 +Nc1cccc(CN2C(=O)N(Cc3ccc4[nH]ncc4c3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)c1 +Oc1ccc2c3c1OC1c4nc5ccccc5cc4CC4(O)C(C2)N(CC(F)F)CCC314 +COc1cc[nH]c1C=C1C(=O)Nc2ccc([N+](=O)[O-])c(N3CCC(N)C3)c21 +NC(=O)c1ccc(N2CCC(NC(=O)c3ccc(F)c(F)c3)C2)c2cncnc12 +CCOC(=O)c1cc(C(=O)OC)c(C)nc1N1CCC(NC2CCCCC2O)CC1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccccc3C)NC(=O)NC1=O)C2 +CCc1nc2c(c(OCC(F)(F)F)c(C(=O)NC3CCN(C(=O)CO)CC3)n2C)c(=O)n1CC(=O)c1ccccc1 +NC(=O)c1sc(-n2cnc3ccccc32)cc1OCc1ccccc1Br +CC(C)CC(NC(=O)C(Cc1cccnc1)NC(=O)N1CCOCC1)B(O)O +C=CCN(C(=O)NCc1ccc(F)cc1F)C1CCN(CC2CN(C(=O)C3CCCC3)CC2(O)c2ccccc2)CC1 +CC(C)n1nc(-c2cc(-c3cccs3)on2)c(C(N)=O)c1N +N#Cc1cccc(Cn2c(CC3(C(=O)O)CCCC3)nc3cc(OCc4ccc5ccccc5n4)ccc32)c1 +O=C(Nc1ccc(CCNc2ncnc3oc(-c4ccccc4)c(-c4ccccc4)c23)cc1)c1ccccc1 +Cn1c(Cc2nc3c(F)c(F)cc(F)c3[nH]2)nc2ccc(C(=O)NC(CP(=O)(O)O)C(=O)O)cc21 +CC1COCCN1C(=O)c1ccc(Cl)cc1NS(=O)(=O)c1cccc2nccnc12 +COc1c(OC2CCC2)ccc2c1CCN(Cc1ccc(C(C)NC(C)=O)cc1)C2 +Cc1cc(C)[n+](-c2ccc(S(=O)(=O)Nc3nnc(S(N)(=O)=O)s3)cc2)c(C)c1C +O=C(C(Nc1ccccc1F)c1ccc(C(F)(F)F)cc1)N1CCCC1c1cccnc1 +N#Cc1cc(Oc2cncnc2)cc(C(=O)Nc2ccc(F)cn2)c1 +O=C(O)CC(NC(=O)CN1CCC(CCc2ccc3c(n2)NCCC3)C1=O)c1cccc(F)c1 +O=C(CCn1c2c(c(=O)[nH]c1=O)COCC2)NCC(=O)N1CCN(c2ncccn2)CC1 +N#Cc1cc(C(=O)Nc2cc(-c3ccccc3)nn2-c2ccccc2Cl)ccc1-c1ccc(F)cc1 +O=C(c1ccccc1)N(O)CCC(c1ccc(Cl)c(Cl)c1)P(=O)(O)O +CCC(Nc1cc(CNCCC(=O)O)c(Cl)cn1)c1ccc(Cl)c(C)c1 +O=CC(CC(=O)O)NC(=O)C1CCCN2C(=O)CCC(NC(=O)OCc3ccccc3)C(=O)N12 +COC(=O)C(C)(C)Cn1c(=O)[nH]c(=Nc2ccc(Cl)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O +N=C(N)Nc1ccc(C(=O)Oc2ccc(CC(=O)NC(Cc3ccccc3F)C(=O)O)c(Cl)c2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(c2ccc(F)cc2)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1cc(F)cc(C(F)(F)F)c1 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCN(c5nncs5)CC4)ncn3)c2c1 +COc1ccccc1N1CCN(CCCCNC(=O)C=Cc2ccc(-c3ccccc3)cc2)CC1 +O=C(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1cc2cc(O)ccc2n1Cc1cccc(C(F)(F)F)c1 +CCCN1C2CCC1C(C(=O)OC)C(c1ccc(F)cc1)C2 +O=C(NC(Cc1ccccc1)C(=O)NC(C=CS(=O)(=O)c1ccccc1)CCc1ccccc1)c1cc(F)cc(F)c1 +O=C(Nc1ccc(N2CCN(C(=O)C3CCC(C(=O)O)CC3)CC2)cc1)c1nc(-c2ccccc2)oc1C(F)(F)F 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+NC(=O)C(CCc1ccccc1)NC(=O)C(N)Cc1ccccc1 +CC(C)(C)c1ccc(-c2cc(=O)cc(N3CCOCC3)o2)cc1 +O=C(c1nc2nccc(C(=O)NC3CCCNC3)c2[nH]1)c1cccs1 +O=c1[nH]c(-c2cccs2)nc2cn(-c3ccccc3)nc12 +Brc1ccc(C2=NN(c3ccccc3)C(c3cccc4ccccc34)C2)cc1 +Cn1cc(-c2cc(C(N)=O)nc3cc(CN4CCCCC4CF)ccc23)cn1 +NCCC(O)CNC1CC(N)C2(CCC(O)C(O)CO2)C(O)C1O +O=C(O)C(=O)CC(=O)c1cccc(Cc2cccc(F)c2)c1 +CC(=N)NCCNc1c2c(c(NCCNC(C)=N)c3sccc13)C(=O)c1ccccc1C2=O +COCCNC(=O)c1ccc(Nc2ncc3cc(-c4ccncc4)ccc3n2)cc1C +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2CC(=O)NCC2CC2)cc1 +CNc1nc2cc(-c3cccc(CCNC(N)=O)c3)sc2n2c(C)cnc12 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2cc(F)cc3c2OCOC3)[nH]c1=O +CCCCN(CCC)c1nc(C)nc2c(-c3c(C)cc(N(C)C)nc3C)c(C)nn12 +CC(C(=O)NCc1ccc(C(C)(C)C)cc1)c1ccc(NS(C)(=O)=O)c(Br)c1 +O=C(Nc1ccc(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cc1)NN1CCCCC1 +NCCCCC(NC(=O)C1CC1)C(=O)c1noc(Cc2ccc(OCCc3ccc(Cl)c(Cl)c3)cc2)n1 +COc1ccccc1C(=O)N1CCCN(CC(=O)NC2CC(=O)OC2O)C(=O)C(NC(=O)c2ccc3ccccc3c2)C1 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+CNC(=O)c1cccc(Nc2ncnc(N3CCC(c4csc(-c5ccccc5)n4)CC3)n2)c1 +Cc1cc(-c2cn(CC3CNC3)c(C3CCN(c4ncnc(N)c4OCC(F)(F)F)CC3)n2)ccc1F +Cc1c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)ccc2cc(C#N)ccc12 +COc1cc(OC)cc(-c2nccnc2C2CN(C(=O)c3nc4ccccc4[nH]3)C2)c1 +CN1CCC=C(c2nsnc2OCCCCCCCCCCCCOc2nsnc2C2=CCCN(C)C2)C1 +CC(=O)NCCc1c(Cc2ccccc2)oc2ccc(O)cc12 +CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1ccc(C(=O)O)cc1Cl +CCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ncnc(NCC5CC5)c4Cl)C3)cc2)s1 +O=C(CCCCCCNC(=O)N1Cc2ccccc2C1)NCCCc1ccccc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCN(C(=O)OCc2ccncc2)CC1 +Cc1cc(COc2ccc(S(=O)(=O)N3CCCC(C)(C(=O)NO)C3)cc2)c2c(n1)CCCC2 +O=C(Nc1cccc(F)c1)Nc1cc(C(=O)NCCN2CCCC2)ccc1Oc1ccc(F)c(F)c1 +O=P(O)(O)OC1C(O)C(OP(=O)(O)O)C(F)(F)C(O)C1OP(=O)(O)O +Cc1cc(C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)n(-c2ccccc2N)n1 +O=C(O)c1ccc(N2CCC(CN3CCC(Oc4ccc(Cl)c(Cl)c4)CC3)CC2)cc1 +O=C(O)CC(NC(=O)C1CCCN(C(=O)CCC2CCNCC2)C1)c1ccccc1 +CN1C2CCC1CC(OC(=O)c1cn(CC(F)(F)F)c3ccccc13)C2 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3cccc(Cl)c3)cc2)C(=O)C(C)C)c1 +CCCCC(C=O)NC(=O)OC(C)(C)Cc1ccccc1Cl +Oc1cccc(F)c1-n1nc(OC2CCNCC2)c2c1CCCC2 +CC(OCc1cc(Cl)cc(-c2cc(NC(=O)C3CNC(=O)N3)nn2-c2ccc(F)cc2)c1)C(F)(F)F +COC(=O)C1=C(Nc2ccc(C)cc2)OC(=Cc2c[nH]c3ncccc23)C1=O +CC1CN(C(=O)C(C)(O)C(F)(F)F)CCN1S(=O)(=O)c1ccc(C(C)(C)C)cc1 +Cc1sc(NC(=O)C2CCCCC2C(=O)O)c(-c2nc(C3CC3)no2)c1C +COc1ccc(COc2ccc(Cn3c(N)nc4cc(-c5cnn(C)c5)cnc43)cc2OC)cn1 +CN(CC(=O)NC(CCCCN)C(=O)C(=O)Nc1ccccc1)C(=O)c1ccccc1Sc1ccccc1C#N +COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCSCC5)cn4)ccc23)c(Cl)cc1Cl +NC1CCN(S(=O)(=O)c2ccccc2-c2ccc(-c3cnc4[nH]ccc4n3)c(F)c2)CC1 +Brc1cnc(Nc2cccc3ccccc23)nc1Nc1cc(C2CC2)[nH]n1 +Cc1cc(C)cc(COC2C3CCN(CC3)C2C(Cc2ccccc2)c2ccccc2)c1 +Cc1cc(NC(=O)C(=O)O)cc(C)c1Oc1cccc(-c2ccccc2)c1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1Cc2cc(-c3cc4ccccc4o3)ccc2CC1C(=O)O +COc1cc(CC(=O)NCc2ccc(C(C)(C)C)cc2)ccc1O +Cc1cc(Nc2nc(Sc3ccc(NC(=O)CN4CCC(C(=O)N5CCC(F)(F)C5)C4)cc3)nn3cccc23)n[nH]1 +O=C1CC2OC(Cc3ccccc3)C(OCc3ccccc3)C2O1 +Cn1ncc2cc(-c3ccc4oc(NC5CCCCC5)nc4c3)ccc21 +O=S(=O)(c1cccnc1)N(Cc1ccc(C(F)(F)F)c(F)c1)c1sc2ccccc2c1Br +O=CN(O)C(CCc1ccc(C(=O)O)cc1)CS(=O)(=O)c1ccc(Oc2ccc(OC(F)(F)F)cc2)cc1 +O=C(NCc1ccccc1)Oc1ccc2c(c1)C13CCCCC1C(C2)N(CC1CC1)CC3 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(C(=O)NC2CC2)cc1 +O=C(CSc1snnc1-c1ccc(Br)cc1Br)Nc1ccccc1Cl +CCOC(=O)c1c(-c2cccc(OC(F)(F)F)c2)[nH]c2cc(OC)c(F)cc2c1=O +Cc1cc(COc2ccc(S(=O)(=O)CC(CC3CCC(=NO)CC3)N(O)C=O)cc2)c2ccccc2n1 +COc1cc2c(N3CCN(C(S)=NCc4ccc(C(F)(F)F)nc4)CC3)ncnc2cc1OCCCN1CCCCC1 +CC(=O)Nc1ccc2cccc(Oc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2n1 +NC1CC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(Cc2ccccc2)C(=O)NC(Cc2ccccc2)CNC1=O +N#CC1(NC(=O)Cc2nnc(Cc3nc4ccc(-c5ncccn5)cc4s3)o2)CC1 +CCc1cnc(N2CCC(n3nnc4cc(-c5ccc(S(C)(=O)=O)cc5)ccc43)CC2)nc1 +CC(C)c1ccccc1NC(=O)N1CCOc2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc21 +COc1cc(C(C)C#Cc2c(C)nc(N)nc2N)ccc1-c1ccccc1C +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1OC(=O)NC +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4ncccc4n3)cc2)no1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3cccc(OC)c3OC)ncc2C(F)(F)F)c1 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+O=C(Nc1n[nH]c2nc(-c3cccs3)c(Br)cc12)C1CCCC1 +CN(C)CCNc1cc(Nc2cc(C3CC3)[nH]n2)nc(-c2ccccc2)n1 +CC(C)Oc1cc(N2CCC(Oc3ccc(C(C)NC(=O)C(C)F)cc3)C2)ccn1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CCC(O)CC4)c4ccccc4n3)c(C)c12 +Cc1cc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)c(CN4CCOCC4)n2CCO3)no1 +O=CC1CCCN1C(=O)C1Cc2ccccc2N1C(=O)OCc1ccccc1 +CC(C)N(c1ccccc1)S(=O)(=O)c1ccc(O)cc1 +CC1CN(C(C)C)C(=O)c2cccc(NC(=O)c3cccnc3)c2OC1CN(C)Cc1ccc(Oc2ccccc2)cc1 +COc1cc(OC)cc(C(C#N)=Cc2ccc(C)cc2)c1 +CN(C)CCCCCNc1c(Br)cccc1Nc1ncnc2ccncc12 +CCCCOc1c(O)ccc2c1C13CCN(CC4CC4)C(C2)C1(OC)CCC(=O)C3 +COCCCCNC(=O)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NCC(c1ccc(Cl)c(Cl)c1)N1CCC(N(CCO)CCO)CC1 +CC(C)c1ccccc1OCC(O)CN1CCC(CN2C(=O)CCCC2=O)CC1 +O=C(C=Cc1ccc(F)cc1)Nc1cc(-c2ccccc2)[nH]n1 +COc1ccc(N2CCN(c3nc(Nc4cc(C(C)(C)C)ccc4C)cc(S(C)(=O)=O)n3)CC2(C)C)cc1 +CCOC(O)=C1C(COCCNc2n[nH]c(N)n2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1 +NC(=O)Cc1ccccc1CCc1nc(Nc2ccc(C3CCNC3)cc2)ncc1C(F)(F)F 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+COc1cc2nc(-c3nccs3)n(-c3cc4nc(N)nc(N)c4cc3Cl)c2cc1OC +Cc1cccc(C(=O)N2CCC(N3CCC(n4c(=O)[nH]c5ccccc54)CC3)CC2)c1 +c1ccc(C(OCCCc2c[nH]cn2)c2cccnc2)cc1 +CCc1nc(N)nc(N)c1-c1ccc2c(c1)N(CCCOC)C(=O)C(C)(C)O2 +Cc1c(F)cc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC(C)C)cn1 +CCCOc1cccc(CNC(=O)Nc2nc(-c3ccncc3)cs2)c1 +COC1CN(c2cccc(-c3cc(C)ccc3OCc3ccc4c(c3)CCN(C3CCOCC3)C4)n2)CCC1C(=O)O +COc1cc(C#CC(=O)OCCCCN(C)CCCCOC(=O)c2c3ccccc3cc3ccccc23)cc(OC)c1OC +CC(=O)C1CCC2C3CCC4CC(O)C(N5CCOC(C)C5)CC4(C)C3CCC12C +NS(=O)(=O)NCC1OC(n2cnc3c(NCc4cccc5ccccc45)ncnc32)C(O)C1O +CCC(=O)NCC1=Cc2ccccc2C(c2ccccc2)C1 +Cc1nnc(N2C(=O)c3cccc4c([N+](=O)[O-])ccc(c34)C2=O)s1 +O=S(=O)(Nc1ccc(F)c(C#Cc2cnc3[nH]ccc3c2)c1F)c1cccc(Cl)c1 +CC(Oc1ncccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(F)c12)C(F)(F)F +O=C(NNCc1ccc(Cl)cc1)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 +CC(C)=CCOc1cc(Oc2ccc(S(=O)(=O)N3CCC(F)C3)cc2)cc(C(=O)Nc2ncc(F)s2)c1 +CC1CC2CC(C1)CC(N1C3CCCC1CC(n1c(=O)c(C(=O)O)nc4ccccc41)C3)C2 +O=C(NCc1ccc(F)c(F)c1)c1c(C2CCCC2)n(Cc2ccccn2)c2ccc(O)cc12 +CC#Cc1cc(C2(c3ccc(OC(F)F)cc3)N=C(N)N(C)C2=O)ccc1F +Cc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1 +COc1ccc(C=CCN2CCN(CCOC(c3ccccc3)c3ccccc3)CC2)cc1 +Cc1cc(-c2nc3cc(C(=N)N)ccc3[nH]2)c(O)c(-c2cc(CNC(N)=O)ccc2O)c1 +CCOc1cc(C2C(C(=O)OC)=CNC=C2C(=O)OC)cc(Br)c1OCC +Cc1[nH]c(C)c(-c2ccc(-c3ccc(Cl)cc3)cc2)c(=O)c1Cl +COc1cc2c(cc1OC)C(=O)C(=Cc1ccc(N3CCN(c4ccccn4)CC3)cc1)C2 +Cc1c(Cl)cccc1-c1cccc(COc2ccc(C(CC(=O)O)c3nccn3C)cc2)c1 +COc1ccc2c(Nc3c(Cl)cncc3Cl)cc(=O)oc2c1OCCCCCCC(=O)O +CSCCC(NC(=O)C1CC(Oc2ccc(-c3ccccc3)cc2)CN1CC=CC(N)CS)C(=O)O +COc1ccc(CC(=O)Nc2cc(-n3nc(C)cc3C)nc(-c3ccc(C)o3)n2)cc1 +CNc1nc(Nc2cc3c(cc2OC)N(C)C(=O)C(C)(C)O3)ncc1C(F)(F)F +CC1CN(C(=O)OC(C)(C)C#N)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)c3nccc(N)n3)cc2F)cn1 +CCCOc1cc2c(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)CC3)ncnc2cc1OC +O=S(=O)(Nc1ncc(F)s1)c1ccc2c(-c3ccc(C(F)(F)F)cc3C3=CCNCC3)cccc2c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(Cl)s4)nc23)N1 +CC(C)(O)C1CCCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C 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+O=C1CC(CN2CCN(c3ccccc3)CC2)Cc2occc21 +COCc1ccc2c3nc(N4CCCC(N)C4)n(Cc4ccccc4Cl)c3c(=O)n(C)c2c1 +Cc1cccc2cc(C(C)Nc3ncnc4[nH]nc(Cl)c34)n(-c3ccccc3)c(=O)c12 +CCN1C(=O)c2nc(-c3ccc(-c4ccc(F)cc4F)nc3)n(Cc3ccc(F)c(F)c3)c2N2CC(C)(C)N=C12 +Cc1cccc(-c2[nH]c(CNc3cccc(C(N)=O)c3)nc2-c2ccc3nccnc3c2)n1 +COc1cc2c(cc1OC)C(CC(O)c1ccc(Cl)cc1)N(C)CC2 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1CCc1cccn1C +Cc1ccccc1NC(=O)C1CCCN1S(=O)(=O)c1ccccc1C(F)(F)F +CC1C2Cc3ccccc3C1(C)CCN2C(=O)C1COc2ccccc2O1 +Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1-c1cccc(CNC(=O)CO)c1 +COc1cccc(OCC(=O)NC(Cc2ccccc2)C(O)C(=O)N2CSC(C)(C)C2C(=O)NC2c3ccccc3CC2O)c1 +CN(CCOc1cccc(NC2=C(c3c[nH]c4ccccc34)C(=O)NC2=O)c1)c1ccnc(F)c1 +CC1CCN(C(=O)C(CCCN=C(N)N)NS(=O)(=O)c2cccc3c2CCCC3)C(C(=O)O)C1 +Cc1nc(NC(=O)NC(c2ccccc2)C(C)(C)O)cc2[nH]nc(OCCO)c12 +Cc1ccc(NC(=O)C=CC(=O)N2CC(=Cc3ccccc3)C(=O)C(=Cc3ccccc3)C2)cc1 +O=C(NCc1ccc(N2CCOCC2)cc1)n1sc2ccccc2c1=O +Cc1cc2nc(C)c(CN3CCN(c4ccccn4)CC3)n2c(C)n1 +CCCCCCCCCCCCOc1ccc(C[S+]([O-])c2ccc(C(=O)O)cc2)nc1C=CC(=O)O +Cc1ccc(Cn2c(C)c(C)n3c4c(=O)[nH]c(=O)n(C)c4nc23)cc1 +COc1ccc(F)c(CC2CCN(CCc3ccccc3)CC2)c1 +CC1(O)CN(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)C1 +CC(C)CS(=O)(=O)c1ccc(C=NNC(=O)c2ccc(O)c(Cl)c2)c2ccccc12 +O=c1[nH]cccc1-c1cccn2nc(Nc3ccc4ncccc4c3)nc12 +Cc1c(C(=O)NCC(O)CN2CCN(c3cccc(Cl)c3Cl)CC2)nc(-c2ccccc2)n1-c1ccccc1 +CCc1cccc(C2=CCN(C(=O)C3NCC4(CC4)CC3C(=O)NO)CC2)c1 +COc1ccc(-c2cc3nc(C)c(C)c(N4CCN(C(=O)c5ccco5)CC4)n3n2)cc1 +CN=C(S)C1=CC(C)(C(F)(F)F)Oc2ccc([N+](=O)[O-])cc21 +COc1cc([N+](=O)[O-])ccc1NC(=O)Nn1cnnc1 +O=C(CCC1CCN(Cc2ccccc2)CC1)c1cc2c3c(c1)CC(=O)N3CCC2 +CCOCC1COC(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)c(F)c3)c2n1 +CCN1CCC(c2ccn3c(-c4ccnc(N)n4)c(-c4ccc(F)cc4)nc3c2)CC1 +O=C1NCC(=O)N(Cc2ccc(Cl)cc2)C1Cc1c[nH]c2ccccc12 +N#Cc1ccc(N2CCN(C(=O)c3nn(-c4ccccc4Cl)c(-c4ccc(Cl)cc4)c3CC(N)=O)CC2)nc1 +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3ccc4c(COC(=O)C(N)CO)cccc4n3)c(C)c12 +COc1cc(OCc2cccc(-c3nc(CO)c(C)s3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C(O)CCc1ccccc1-c1cccc(-c2ccccc2OCc2ccccc2)c1 +Oc1cc2c(cc1O)C(Cc1cc(I)c(I)c(I)c1)NCC2 +COc1ccc(N2C(=O)c3c(Cl)cccc3C2C)cc1OCCN1CCC(C)CC1 +COc1cc(F)cc(-c2ccc(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccon5)ccc43)c(OC)c2)c1 +CCN1C(C(=O)NC(Cc2ccccc2)C(=O)C(=O)NC(C)C)Cc2cc3c(cc2S1(=O)=O)OCCO3 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(N)c2)n1C +O=S(=O)(Nc1ncns1)c1ccc(Oc2ccc(-c3ccccc3)cc2)c(Cl)c1 +NS(=O)(=O)OCC1CC(Nc2cc(NC3CCc4ccccc43)ncn2)CC1O +CCCCCN(CCCCC)C(=O)C(CCC(=O)O)NC(=O)c1cc2ccccc2[nH]1 +COCCOc1n[nH]c2cc(NC(=O)NCC(C)c3ccccc3)ncc12 +CC(Oc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(c2cnc(C(F)(F)F)cn2)CC1)C(F)(F)F +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C(C)CNCc1ccccc1C(C)C +CN(C)CCCCN(Cc1nc2ccccc2[nH]1)C1CCCc2cccnc21 +CS(=O)(=O)N(Cc1ccc2ccc(C(=N)N)cc2c1)c1ccc(-c2ccccc2S(N)(=O)=O)cc1 +CC(=O)Nc1cnc2c(ccn2-c2cc(NC(C)C)c(C(=O)NCC(F)C(C)(C)O)cn2)c1 +CCCOc1ccc(N2CC(c3ccc(CC(C)NC(C)=O)cc3)C2)c(OC)c1 +Cc1cc(C)[n+](CC(=O)Nc2ccc(S(N)(=O)=O)cc2Br)c(C)c1 +O=C(CN1C(=O)C2C3CCC(C3)C2C1=O)N1CCCC(c2ncncc2-c2ccncc2)C1 +O=C(NO)C(Cc1cccc(Oc2ccccc2)c1)C(=O)N1CCc2ccccc2C1 +Cc1c(N(Cc2ccc(F)c(Cl)c2)S(=O)(=O)c2ccccc2)nc2ccc(Cl)cn12 +CC(NC(=O)N(C)C)c1ccc(OC2CN(c3ccc(OC4CC4)cc3)C2)cc1 +Cc1cc2oc(Cc3cccc(Cl)c3)nc2c(NCC(F)(F)c2ccccn2)n1 +COc1ccccc1-c1cc2c(NC3C4CC5CC3CC(O)(C5)C4)c(C(N)=O)cnn2c1 +Cc1c(C(=O)NC(=O)CC(C)(C)C)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CCCC(O)C(CNCc1ccc(C)cc1C)NC(=O)CC(=O)Nc1cc(C(F)(F)F)ccc1NC(=O)OC(C)(C)C +CCOC(=O)c1c(NCCN(C)C)n(-c2ccccc2)c(=S)n(-c2ccccc2)c1=O +NC(=O)c1cc(-c2ccncc2)[nH]c1-c1cccc(F)c1 +Cc1nc2cc(-n3ncc(C(=O)c4cc5cc(-n6ccnc6)ccc5[nH]4)c3N)ccc2[nH]1 +CCCN1C(=O)CN(Cc2ccc(-c3ccc(F)c(CN4CCCCC4)n3)cc2)C1=O +O=[N+]([O-])C=Cc1cccc(OCc2ccc(F)cc2)c1 +CC(C)(C)CN1CCC(c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)CC1 +CC1CN(c2ccc3ccccc3n2)CCN1CCCN1C(=O)c2ccccc2C1=O +CCN(CC)CCOc1ccc(-c2cc(C(=O)Nc3cccnc3)c(NC(N)=O)s2)cc1 +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(OC)cc3Cl)ccnc21 +O=C(c1ccc2c(c1)C(O)(C(F)(F)F)c1ccccc1-2)c1cccs1 +CN1CCN(c2ccccc2NC(=O)c2ccc([N+](=O)[O-])o2)CC1 +CCCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)CN(C)CC3)cc1 +N#Cc1cccc(C(=O)N2CCCCC2CCOc2ccc(Cl)c(Cl)c2)c1 +CCOCC(CC(C)C)NC(=O)C1CNCC(C(=O)N(c2cc3c(cc2F)OC(C)(C)C(=O)N3CCCOC)C2CC2)C1 +COCC(NC(=O)Nc1cc2[nH]nc(-c3ccc4c(c3)nnn4C)c2cn1)c1ccc(F)cc1 +CC1CN(c2cncnc2)Cc2cc(C(=O)Nc3cc(CN(C)C)cc(C(F)(F)F)c3)ccc21 +CC1(O)C(O)C(CO)OC1n1cnc2c(NCc3ccccc3)ncnc21 +CCCCc1nn(C(C)CC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(NCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2)c1c[nH]c2ccccc12 +NC(=O)c1cc(-c2ccncc2)cc(-c2ccc(S(N)(=O)=O)cc2)c1N +CC(C)(NC(=O)c1nn(-c2ccc(F)cc2F)c2c1CC1CC21)c1ccncc1 +O=C(Nc1nc2ccccc2n2cncc12)c1c(Cl)cccc1Cl +CC(=O)c1cccc(-c2cc(N3CC(N)C(c4cc(F)c(F)cc4F)C3)ncn2)c1 +Cc1ccc(F)c(Nc2ccc(-c3cnc4ccc(NC5CCC(N)CC5)nn34)cc2)n1 +O=C(OCCF)C1C2CCC(CC1c1cccc(C=CI)c1)N2 +O=C(C[S+]([O-])C(c1ccc(F)cc1)c1ccc(F)cc1)N1CCN(CCCc2ccccc2)CC1 +COc1cc(N2Cc3ccc(-c4ccc(C)c(C)c4)nc3C2=O)ccc1OCCN1CCCC1 +CC(C(O)c1ccc2c(c1)CC(=O)N2)N1CCC(Cc2ccccc2)CC1 +O=C(CSC(=S)NN1CCN(c2ccccc2)CC1)NCc1ccc2c(c1)OCO2 +CC(=NOC1CCNC1)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +NC1=NC(CF)(c2cc(C#Cc3ccc4[nH]ccc4c3)ccc2F)CC(C(F)(F)F)O1 +Cn1cc(NC(=O)c2cc(NC(=O)c3ccc(C=Cc4nc5ccccc5o4)cc3)cn2C)cc1C(=O)NCCN1CCOCC1 +C#CCCCC#Cc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +Cn1nc2c(c1Cc1cccc(C(F)(F)F)c1)CC(N)C(=O)N2O +CC(C)c1nc2c(c(Nc3ccc(Cl)c(Cl)c3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +O=C(NC1=NN(c2ccccc2)C(=O)C1)Oc1ccccc1 +O=C(Nc1c(Cl)cncc1Cl)C(=O)c1cc(Cc2ccc(O)cc2)n2ccccc12 +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1Br)c1ccc2ccnc(N)c2c1 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2cc(Cl)ccc2Cl)C1 +CCCc1c(C(=O)OCC)c(C(=O)OCC)c2c(-c3ccccc3F)cc(N3CCOCC3)nn12 +O=c1cc(-c2cccc([N+](=O)[O-])c2)oc2ccc(Br)cc12 +CC1CCN(CCCOc2ccc3c(c2)N(Cc2ccc(F)cc2)C(=O)CC3)CC1 +N#CC(CC(N)=O)NC(=O)C1CCCN1C(=O)OCc1ccc(-c2cc(F)cc(F)c2)cc1 +O=S(=O)(Nc1ccc2c(C=Cc3ccc4ccc(Cl)cc4n3)cccc2c1)C(F)(F)F +CC(C)CNc1nc(C#CC2CCCCC2)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +Cc1cc(C(=O)O)c2[nH]c(-c3c(F)c(F)c(-c4cccc(OCc5ccccc5)c4)c(F)c3F)nc2c1 +O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1cc(Cl)ccn1 +O=C1NC(=O)C(=Cc2ccc(OCCNc3nc4ccccc4s3)cc2)S1 +Cn1cc(NC(=O)c2csc3ncc(NC4CCCCC4N)nc23)c(C(F)F)n1 +CCc1nc(-c2cccc(Cl)c2)c(-c2ccnc(NC(=O)c3ccccc3)c2)s1 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2noc(COc3ccccc3O)n2)cc1 +NC(CC(CP(=O)(O)O)=NOCc1ccccc1)C(=O)O +Cc1nc(NC2CCSCC2)nc(-n2ccnc2C)c1[N+](=O)[O-] +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(Cl)c(-c2nc3ccccc3n2C)c1 +Cc1ccc(C(=O)Nc2ccc(C#N)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCCC3)nc12 +CCc1cc2c(cc1F)c(C#N)c(-c1ccc(S(=O)(=O)NC(C)C(F)(F)F)cn1)n2-c1ccc(F)cn1 +Cc1cc(-c2cccc(O)c2F)cc2nnc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nc12 +CCCCCCn1ccnc1C=CC(=O)C=Cc1nccn1CCCCCC +CN(C)C1CN(c2ncc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncc(F)c2)CC1O +Cc1nc(Cl)c(Sc2ccc(Cl)cc2)c(N2CCN(C)CC2)n1 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(OCCCN3CCCC3)cc2)nc1 +COC(=O)C(NP(=O)(OCC1OC(C)(C)OC1C(=O)NO)Oc1ccc(C)cc1)C(C)C +COc1ccc2c(c1CN1CCNCC1C)OC(=Cc1n[nH]c3ncccc13)C2=O +CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(NC(=O)c3ccncc3)c3ccccc23)CC1 +COc1cccc(N2CCN(CCNCCc3ccccc3)C(Cc3ccc(O)cc3)C2)c1 +CCc1ncnc(N2CCC(CC(C)(C)O)CC2)c1C#Cc1ccc(N)nc1 +COc1ccc(-n2nc(CC(C(=O)O)c3ccccc3OC)cc2-c2ccc(C)cc2)cc1 +CCc1nccc(-c2ccc(C(=O)N3CCN(CCOC)CC3)c(F)c2)c1C#Cc1ccc(N)nc1C +O=C1c2c(c(O)c3nccnc3c2O)C(=O)N1Cc1ccc(Br)cc1F +CCc1cc(CN(CC2CC2)C(CC(=O)O)c2ccc(Cl)c(Cl)c2)ccc1OCCN1C(=O)CCC1=O +CCC(CC)(C(=O)O)c1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1 +CCCNc1nc(C)c(-c2nc3ccccc3s2)c(NC2CC(CO)C(O)C2O)n1 +COc1cc(C)c(Nc2nc(C)cn(C(CF)C3CC3)c2=O)cc1C +Nc1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 +CN1CCC(O)(C#Cc2ccc3c(c2)-c2nc(C(N)=O)sc2C(O)(C(F)(F)F)CO3)C1=O +Cc1cc(C(=O)N2CCCCc3ccccc32)ccc1CNC(=O)N1CCCC1C(=O)OC(C)(C)C +CCOc1cc2ncnc(Nc3ccc4c(ccn4S(=O)(=O)c4ccccc4)c3)c2cc1NC(=O)C=CCN(C)C +CC(C)C1CNC(=O)c2cc(-c3cccc(OC(F)(F)F)c3)c(-c3ccc(CN)cc3)n21 +Cc1ncc(-c2ccnc(Nc3ccc(N4CCN(C(=O)CN(C)C)CC4)cc3)n2)n1C(C)C +O=C(NC(C(=O)NC1CCCc2ccccc21)c1cccnc1)c1ccc(-n2cncn2)cc1 +Cc1cccc2c1OP(=O)(OCC1CCC(n3cnc4c(O)ncnc43)O1)OC2 +CC1OC(n2cc(-c3ccccc3)c3c(NCC(=O)N(C)C4CC4)ncnc32)C(O)C1O +Cc1ccc(Nc2nc(-c3ccccn3)cc(N3CCCC(O)C3)n2)cc1 +Cc1cc(OCC2(C(=O)O)CCC2)ncc1-c1cnc(-c2ncc(C(F)(F)F)[nH]2)c(F)c1 +O=C(CCCc1ccccc1)N1CCN(CCCC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +COC(=O)OC1Cn2c(-c3ccnc(Oc4ccccc4)n3)c(-c3ccc(F)cc3)c(=O)n2C1 +COc1cc(C(=O)OCCCCN2CC(C)N(CCCCOC(=O)c3cc(OC)c(OC)c(OC)c3)CC2C)cc(OC)c1OC +CCC1CCCC(C2(OC(=O)N3CCC(O)(CC)CC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +CCn1c(-c2ccccc2)cc2onc(-c3ccccc3)c2c1=O +O=S(=O)(Nc1ncns1)c1ccc(Oc2ccccc2-c2ccccc2)c(Cl)c1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(CCF)CC1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1cccc(NC(=O)NCCCN2CCCCC2)c1 +O=C(NC1C(CO)OC(n2cnc3c(NC4CCCC4)ncnc32)C1O)c1ccc(Cl)c(Cl)c1 +Cn1c(CF)nc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3c21 +COc1ccc(CCCCOc2ccc(CSCc3cccc(C(=O)O)c3)nc2CCC(=O)O)cc1 +O=C(c1ccc(OC(F)(F)F)cc1)c1ccn(-c2cc(F)c(O)c(F)c2)c1 +Nc1ncc2cc(Cc3nnc4ccc(-c5ccccc5)nn34)ccc2n1 +O=C(Nc1ccc(C2CCNC2)cc1)c1ccc(Cl)cc1Cl +Cc1nc(CNc2nc(OCC3CC3c3ccc4ncccc4n3)nc(Cl)c2C)n(C)n1 +O=C(Cn1cncn1)c1ccc2[nH]c3c4c(c5c(c3c2c1)C(=O)NC5=O)CCC4 +O=C(NS(=O)(=O)C1CC1)c1cc(Cl)c(OC2CCC(F)(F)CC2)cc1F +CCCCc1ccc(NC(=O)CSc2nnc(-c3ccccc3N)[nH]2)cc1 +Cc1ccc2c(-c3nnc(SCCCN4CCc5cc6nc(C7CC7)oc6cc5CC4)n3C)cccc2n1 +CCCCCCC(NC(CCc1ccccc1)C(=O)NC(CCCN=C(N)N)C(=O)NC(CCC(N)=O)C(=O)OC)C(=O)O +N#Cc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2C2CNC2)CC1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cccc3ncn(CCc4ccccc4)c2c31 +CCCCCCCCCCCCCCCCS(=O)(=O)NCCCNCCCNCCCCNCCCN +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C(C)=O +CC1COC(c2cccc(OC(=O)NC3CCCC3)c2)=N1 +Cc1c(C(=O)NCCCN2CCN(c3cccc(Cl)c3Cl)CC2)cc(-c2ccccc2)n1C +O=C(NCc1ccc(S(=O)(=O)c2ccccc2)cn1)c1cc2ccncc2o1 +O=C(C=CC=Cc1ccccc1)NCCCCNc1c2c(nc3ccccc13)CCCC2 +Cc1nc2cc(F)ccc2n1C1CC2CCC(C1)N2CCC(NC(=O)c1ccc[n+]([O-])c1)c1cccc(F)c1 +CC1(C)CC(=O)N(CCCCN2Cc3ccccc3C2)C(=O)C1 +C#CCOc1cc(F)c(F)cc1-c1ccc(OCc2cccc(C(=O)N3CCCC3C(=O)O)c2)cc1 +COc1cc2ncnc(Oc3ccc(CC(=O)Nc4ccc(N(C)C)cn4)cc3)c2cc1OC +COc1ccc(C(=O)Nc2ccc(N(C)S(C)(=O)=O)c(OCc3cc(C)ccc3C)c2)cc1OC +CN(C)c1ccc(NC(=O)Nc2ccc(OCc3ccccc3)cc2)cc1 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+Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CCc4ccc(C(=O)c5cccnc5)n4C)c3Cl)c2n1 +Cc1c(Cc2ccc(F)c(C(=O)N3CCC4(CCCN4C)CC3)c2)n[nH]c(=O)c1C +O=C(O)c1ccccc1NC(c1ccccc1)c1ccc(Cl)cc1 +Cc1cccc(NC(=O)NNC(=O)c2cc(-c3ccccc3Cl)nc3ccccc23)c1 +O=C1C(Cl)=C(NCCN2CCOCC2)C(=O)c2cnccc21 +COc1cc2c(cc1OC)C(=O)N1C=C(c3ccc4ccc5cccc6ccc3c4c56)CC1C=N2 +NS(=O)(=O)OCC1CC(Oc2cc(NC3CCc4ccccc43)ncn2)CC1O +Cc1cccc(C2CC2c2ccccc2CCC(=O)O)c1OCc1ccccc1 +Cc1ccc(C)c(N2CCN(CC(O)CN3C(=O)NC(C)(c4ccc(F)cc4)C3=O)CC2)c1 +COC(=O)c1c(SC)nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c1N +CC(=O)OC1=C(c2ccc(C)cc2)Oc2cccnc2-n2cccc21 +CC(C)c1[nH]nc2c1C(c1ccccc1C(=O)O)N(c1ccc(-c3ccsc3)cc1)C2=O +O=C1CCc2cc(-c3cncc(-c4cc(F)cc(F)c4)c3)cc3c2N1CC3 +CCOC(O)=C1C(COCCNC(=O)NCCN)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +NC(=O)C1(c2ccccc2CCc2nc(Nc3ccc(C4CNC4)cc3)ncc2C(F)(F)F)CC1 +N#Cc1ccccc1Nc1cccc(-c2cnc3ccccn23)n1 +CC(C)(C)OC(=O)c1ncn2c1C1CCCN1C(=O)c1cc(Br)ccc1-2 +CC(Nc1nccc(N2C(=O)OCC2C(C)F)n1)c1ccc(-c2ccnc(C(F)(F)F)c2)cn1 +FC(F)Oc1ccc(-c2ccnc3cc(-c4cc(Cl)ccc4Cl)nn23)cc1OCC1CC1 +CC1(C)CCC(C)(C)c2cc3c(cc21)Cc1ccccc1N=C3c1ccc(C(=O)O)cc1 +O=C(Cn1cc(Cc2cnc(C(F)(F)F)nc2)c(=O)nc1SCc1ccc(F)cc1)N1CCN(c2ccc(Cl)cc2)CC1 +CCC1C(=O)N(C2CCN(C(C)CC(c3ccccc3)c3ccccc3)CC2)c2ccccc21 +CN(C)c1ccc(-c2cc(=O)c3cc(OCCOCCF)ccc3o2)cc1 +CC(C)CN(NC(=O)C1CCC2(CC1)OOC1(OO2)C2CC3CC(C2)CC1C3)c1cc(Cl)nc(C#N)n1 +COc1cc2c(cc1OC)-c1c(-c3cncn3C)ncn1CC2 +CCSc1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +COc1ccc(C(CCCN)(c2ccccc2)c2ccccc2)c(F)c1 +O=C(Nc1ccc(N2CCN(C(=O)C3CCCO3)CC2)cc1)N1Cc2ccccc2C1 +CCCC(=O)N1CCN(C(=O)c2nc(-c3ccccc3)nc(CCC)c2C(=O)OCC)CC1C +CCCCCNC(=O)Nc1c(CCC)cccc1OCCCn1cnc(-c2ccccc2)c1C +CC(=O)Oc1ccccc1C(=O)OC(C)OC(=O)c1ccc(SCCCO[N+](=O)[O-])cc1 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCC(=O)N(Cc3cc(F)ccc3F)c3ccccc32)n1 +CC(C)c1cccc(-c2nccnc2C2CN(C(=O)c3nc4ccccc4[nH]3)C2)c1 +CC(C)OC(=O)N1CCC(N2Cc3cn(-c4ccc(S(C)(=O)=O)cc4F)nc3C2)CC1 +CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)cs1 +CSC1OC(c2ccc(C)c(Cc3ccc(OCCCNCC(C)(C)CN(C)C)cc3)c2)C(O)C(O)C1O +Cc1ccc2c(c1)CNC1CCc3cc(O)c(O)cc3C21 +CC1=CC(C)(C)Nc2ccc3c(c21)C(=Cc1cccc(F)c1)Oc1c(F)cccc1-3 +Cc1ccc2c(OCCN3CCC(Cc4cccc(N5CC(C)NCC5C)c4)CC3)cccc2n1 +Nc1ncnc2c1c(-c1ccc3ccccc3c1)nn2CC1CC1 +Nc1cccc(C2=NC(c3ccc(F)cc3)(c3ccc(F)cc3)CN2)c1 +O=C(NC1CC1)c1cnn2ccc(N3CCCC3c3cc(F)ccc3OCCN3CCOCC3)nc12 +CC(NC(=O)C1(NC(=O)c2ccnnc2)CC1)c1ccc(-n2nc(Cl)c3ccccc32)cc1F +COC(=O)c1ccc(-c2sc(N)nc2-c2ccc(P(=O)(O)O)o2)cc1 +C=Cc1nn(-c2ccc(F)cc2)c2c1CCCC2Cc1cccc2ccccc12 +CSCC(NC(=O)c1cccc(CNC(=O)C(N)CS)c1)C(=O)O +c1ccc(-c2c[nH]c(-c3cc4c([nH]c5ccccc54)c(C4CCCCC4)n3)n2)cc1 +CN(C)C(=O)Oc1ccc(CC(Nc2ncncc2-c2ccccc2)C(=O)O)cc1 +COc1ccc(C(=O)NC(C)c2cccc(C(=O)Nc3ccc4c(c3)CN(C)CC4)c2)cc1OC +CC(C)N1CCC(Oc2ccc(CN3CCOCC3)cc2)CC1 +COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2coc(C)n2)cc1 +NC(=O)c1cn(CC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2ccccc12 +Fc1ccc(-c2[nH]c3cc(C4CCNCC4)ccc3c2-c2ccncc2)cc1 +CCOc1cccc(F)c1C1CC(C)C(=O)N1Cc1ccc(OC(F)F)c(Cl)c1 +Fc1cccc(Cl)c1CNc1nc(-c2ccccc2)n[nH]1 +COc1cc(CSc2ncccc2C(=O)Nc2cc(C)cc(C)c2)ccn1 +CCn1c(C(C)NS(=O)(=O)c2ccc(C#N)nc2)nc2cnc(C3CC3)cc21 +NC(=O)C=Cc1cccc2c1nn1cc(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc21 +COc1ccc(C(=O)CSc2cnnn2C2CCCCC2)cc1OC +FC(F)(F)Cn1cc(-c2cnc3nnn(Cc4ccn5nccc5c4)c3n2)cn1 +C#Cc1cccc(Nc2ncnc3ccc(OCCCCCC(=O)NO)cc23)c1 +CC(C)(C)c1cc(=O)[nH]c(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1 +CCCn1ncc(CN2CCCC(C(=O)c3cccc(OC(C)C)c3)C2)c1C +O=C(Nc1ccccc1Br)Nc1ccc(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1Br +Cc1cc(C)cc(S(=O)(=O)N2CCCC2C(=O)NC(Cc2ccc(NC(=O)CCCNC(=N)N)cc2)C(=O)O)c1 +CC(NC(=O)c1nn(-c2ccc(Cl)c(Cl)c2)c2c1CCCC2=Cc1ccc(Cl)s1)c1ccccn1 +CN(C)CCn1cnnc1-c1cc(Oc2ccc(NC(=O)NN=Cc3cccc(O)c3)cc2F)ccn1 +O=C(Nc1nc2c(s1)CNCC2)N1CCC(N2CCc3ccc(F)cc32)CC1 +Cn1c(-c2ccsc2)c(C2CCCC2)c2ccc(C(=O)NC3(C(=O)Nc4ccc(C=CC(=O)O)cc4)CCCC3)cc21 +O=C(Nc1nc(-c2cccc(C(F)(F)F)c2F)cs1)c1ccc(Nc2cc(NCCO)ncn2)cc1 +NS(=O)(=O)c1cccc(N=Nc2ccc(NCS(=O)(=O)O)cc2)c1 +CN1c2ccc(OC(=O)Nc3ccc(Cl)cc3)cc2C2(C)CCN(CCc3ccccc3)C12 +NCCNc1ccc2c3c(nn2CCO)-c2c(O)ccc(O)c2C(=O)c13 +NS(=O)(=O)c1ccc(NNSC(=S)N2CCOCC2)cc1 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+CCCc1nc2c(Cl)ccnc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2c(c1)CC(=O)N2 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CCc4ccccc4)cccc3nc2-1 +c1ccc(Cn2cc(-c3ccnc4ccccc34)c(-c3ccccn3)n2)cc1 +O=C(Nc1ccc(-c2ccnc3[nH]cnc23)cc1)Nc1cccc(Cl)c1 +Cc1cnn(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C3CC3)n2)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CCC(F)(F)F)ncc3F)C2)cc1 +CCCCCCCCCC[N+](C)(CCCCCCCCCC)CCCC1(O)CCC2C3CCc4cc(O)ccc4C3CCC21C +CN(C(=O)c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F)C1CCN(C(=O)c2ccco2)CC1 +O=C(O)c1c[nH]c2cc(Cl)c(-c3ccc(OC4CCCCC4O)cc3)cc12 +Cc1[nH]nc(O)c1C(c1ccc(OCc2ccncc2)cc1)c1c(O)n[nH]c1C +O=C(NC1CCCNC1)c1ccc(O)c2[nH]c(-c3ccccc3)nc12 +C=C1C(=CC=C2CCCC3(C)C(C(C)OCC(=O)OC(C)(CC)CC)=CCC23)CC(O)CC1O +CCN(CC)CCC1=C(C(C)c2ccccn2)c2ccccc2C1 +COc1ccccc1Oc1ccc(Nc2c(C#N)cnn3cc(NC(=O)NCCN4CCOCC4)c(C)c23)cc1 +Cc1cn(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)C2)c2ccc(Cl)cc12 +CC1(C(=O)NC(Cc2ccc(NC(=O)c3ccnc4ccccc34)cc2)C(=O)O)CCCCC1 +CCCCc1nc(SCC(F)(F)F)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 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+CCCCCCCCCOc1ccc(CN2CC(C(=O)O)C2)cc1 +CC(=O)NCc1cccc(Cn2nc(NS(=O)(=O)c3ccc(Cl)s3)c3c(C(F)F)cccc32)c1 +CC(C)c1cc(-c2ccccc2)cc(CC2CCCCC2)c1OCC(O)CC(O)CC(=O)O +NC1=NC2(CO1)c1cc(NC(=O)c3ncc(Cl)cc3F)ccc1OCC21CC1 +COCC(=O)Nc1nc(-c2ccc(F)c(C)n2)c(-c2ccc3nccnc3c2)[nH]1 +COc1cncc(-c2cncc(N3CCN(c4ccncc4)CC3)n2)c1 +CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)no1 +CC(=O)Nc1c(-c2ccccc2)cccc1S(=O)(=O)NC(CCCc1ccc(N)cn1)C(=O)N1CCC(=C(F)F)CC1 +CCCN(CCC)C(=O)c1ccc(C(=O)C(F)(F)F)cc1 +O=C(O)CC(NC(=O)CNC(=O)c1cc(O)cc(NC2=NCCCN2)c1)c1cc(Cl)cc(Br)c1O +O=C(NCCc1cccc(Cl)c1Cl)c1cnc(N2CCN(c3ccncc3)CC2)c(Cl)c1 +Cc1cc(C)cc(C(=O)N(C)C(Cc2ccccc2)C(=O)NCCc2c[nH]c3ccccc23)c1 +COCC(=O)Nc1ccc(F)c(C23COCC2S(=O)(=O)C(C)(C)C(=N)N3)c1 +CC(C)C1=NC2CCC34CC35C(=O)CC3(C)C(C(C)N(C)C)C(O)CC3(C)C5CCC4C2(C)CS1 +N#Cc1cccc(-c2nc(OS(=O)(=O)C(F)(F)F)cc3cccnc23)c1 +COc1ccc2c(c[n+]3c4c2ccc2c5c(cc(c24)CC3)OCO5)c1OC(=O)c1ccccc1F +COc1cc2cncc(Cc3ccc4c(c3)OCCN4C)c2cc1OC +CC(=O)c1sc(NC(=O)NC2CN(CC#N)CCC2CN2CCCC(Cc3ccc(F)cc3)C2)nc1C 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+C=CC(=O)Nc1ccc(C(=O)Nc2ccc(C)c(Nc3nccc(-c4cccnc4)n3)c2)cc1 +O=C(NO)C1CS(=O)(=O)CN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +O=C(O)COc1c(C(=O)O)sc(-c2cccc(NC3CCN(S(=O)(=O)Cc4ccccc4)CC3)c2)c1Br +COc1ccc(CCNCC(O)COc2ccc(-c3nc(C)c(Cl)[nH]3)cc2)cc1OC +CN(C)CCc1c[nH]c2ccc(NS(=O)(=O)c3cccc4ccccc34)cc12 +Cc1nc(-c2ncn3c2Cn2ncnc2-c2cc(F)ccc2-3)no1 +Cc1ncc(-c2nccnc2OC2CC(Nc3nc4ccccc4s3)C2)cn1 +CC(C)OC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCc1ccccc1Cl +CC(CO)NCCNC(=O)C1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +Nc1ccc2c(c1)CN(S(=O)(=O)c1ccc(-c3ccc(Cl)cc3)cc1)C(C(=O)C(=O)O)C2 +N=C(N)NCCCC(C=O)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)COc1ccccc1 +COc1ccc(C(=O)Nc2ccccc2-c2nnn(-c3ccc(Cl)cc3)n2)cc1 +OC(COc1cccc2[nH]ccc12)CN1CCC(c2csc3ccccc23)CC1 +CS(=O)(=O)CCCOc1cccc2c1ccn2-c1ccnc(NC2CCC(C(=O)N3CCC(F)(F)CC3)CC2)n1 +CCCCCCCCCC(=O)CC(=O)Nc1c(C(C)C)cccc1C(C)C +O=C1NCC2c3c(cccc31)CCN2C(=O)c1ccc(Cl)cc1 +C=CC(=O)Nc1ccc2c(c1)[nH]c1c(C(N)=O)c(-c3ccc(Oc4ccccc4)cc3)nn12 +O=C1C2=C(C(=O)c3ccccc31)C1(CS2)NC(=O)N(CCO)C1=O +COc1cc(Cl)ccc1OC1CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 +COCCN(C)c1cc(C(=O)O)nc2c(-c3cccc(O)c3)nc(N3CCOCC3)nc12 +Brc1sc2[nH]nc(N3CC4CC3CC4OCCN3CCCC3)c2c1-c1ccccc1 +CCOC(=O)C1(NC(=O)c2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)CC1 +C#CCn1c(=O)c2[nH]c(C=Cc3ccc4c(c3)OCO4)nc2n(C)c1=O +O=C(c1cccc(CN2CCN(c3cccc4ccccc34)CC2)c1)N1CCCCC1 +COc1ccc(C(=O)NCc2ccccc2)cc1CSc1nc2cc(F)ccc2n1CC(=O)O +NS(=O)(=O)c1ccc(CCNC(=O)CCSSCCC(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +COCC(C)Oc1cc(Oc2cc(F)cc(F)c2)cc(C(=O)Nc2nccs2)c1 +Cn1ccc2cc(C=CC(=O)c3ccc(OS(=O)(=O)c4cc(F)cc(F)c4)c4c3OC(C)(C)C=C4)ccc21 +CC(C)(COc1ccn2c(CC3CC3)nnc2c1C(F)(F)F)c1ccc(F)cc1 +O=C(NC1CCc2cccc3c2N(C1=O)C(C(=O)O)C3)C(S)C1CCCCC1 +CN1C2CCC1CC(NC(=O)C(Cc1ccc(Cl)cc1)NC(=O)Cc1ccc(F)cc1)C2 +Cc1cc(OCC2Oc3ccccc3O2)cc(C)c1C(=O)Nc1cc(CC(=O)O)ccc1Cl +Cc1ccc(-c2cccc(C(=O)N3CCCC(C)(C)C3)n2)cc1F +Cc1noc2ccc(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc43)cc12 +Cc1ccc(-c2ncccn2)c(C(=O)N2C3CCC2C(COc2ccc(F)cn2)C3)n1 +Cc1ccc2nc(-c3ccc(OCC4CCN(C(=O)Nc5ccc(Cl)cc5)CC4)cc3)c(NC(C)C)n2c1 +Cc1n(Cc2c3c(cc4c2OCC4)OCC3)c2ccccc2[n+]1CC(=O)c1ccc2ccccc2c1 +Cc1oc2c(O)c(O)ccc2c(=O)c1Oc1ccccc1F +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCN)sc34)cc2F)c1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Cl)cc1 +Cc1cc(OC(CCCCNCc2ccc(Cl)cc2)C(=O)NO)cc(C)c1F +O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2ccc(Br)cc2F)C2C=CC1C21CC1 +COc1ccc(S(=O)(=O)N(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C(Cc2cccs2)C(=O)NO)cc1 +Cn1c2c(c(CO)c1C1CC1)C(=O)C(N1CC1)=CC2=O +ON=C1CC2(N3CCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2 +Cn1ncc(NC(=O)c2nc(-c3ccccc3F)cnc2N)c1N1CCC(N)C(F)CC1 +OC1CCN(Cc2ccccc2)CC1N1CCC(c2ccccc2)CC1 +CC(C)C(Cl)C(NC(=O)C(O)Cc1ccccc1)C(=O)N1C(C(=O)NCCCCNC(=N)N)CC2CCC(O)CC21 +Nc1ncnc(N2CCC(c3nc(-c4cccc(F)c4)cn3CCN3CCCC3)CC2)c1C1CCC1 +N=C(N)c1ccc(-c2cc(N)cc(-c3ccc(C(=N)N)cc3)c2)cc1 +CCCCCCCCCOc1ccc(N2C(N)=NC(N)=NC2(C)C)cc1Cl +CCCCC(=O)N(Cc1ccc(C(F)(F)F)cc1)c1cc(F)cc(-c2nnn[nH]2)c1 +CN1CCC(c2c[nH]c3ccc(NC(=O)C4CCCCC4)nc23)CC1 +CC(C)(C)c1ccc(NC(=O)C2=CCN(c3nccs3)CC2)cc1 +CCOc1ccc(S(=O)(=O)N(CC(=O)NN=C2C(=O)Nc3ccccc32)c2ccc(C)cc2)cc1 +Nc1nc(-c2cccc(Cl)c2)c(-c2ccc3ncccc3n2)s1 +C1=C(c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)CCOC1 +N#Cc1c[nH]c2c(NS(=O)(=O)c3ccc(N)nc3)cccc12 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCC(=O)N(Cc3ccc(C(F)(F)F)cc3)c3ccccc32)n1 +O=C(NCc1ccc(S(=O)(=O)C2CCN(CC(F)(F)F)CC2)cn1)c1cc2ccncc2o1 +CC1=NOC(CN2CCC(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)C(C#N)C2)C1 +COc1ccccc1N1CC2(CCN(CCCSc3nnc(-c4ccccc4)n3C)CC2)C1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C(N)=O)CC1 +CCOC(=O)C1C2C(=C(O)OCC)C(C)=NC1(C)Sc1ccccc12 +Cc1cc(-c2cc(C(=O)NC3C4(C)CCC(C4)C3(C)C)c(=O)n(Cc3ccc(F)cc3)n2)ccc1Cl +O=C(Nc1ccccn1)Nc1cccc2c1-c1cccn1C2=O +CN(C)CCNC(=O)c1cccc2cc3ccc(F)cc3nc12 +Cc1cc(N2CCOCC2)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +CNC1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(Cl)c(O)c(OC)c4)cc23)CC1 +CN(C)CCc1c[nH]c2ccc(N=C(N)c3cccs3)cc12 +CCC(CC)Nc1nc(OC)c(-c2ccc(Cl)cc2Cl)nc1C +O=C(Nc1ccc(C2CNCCO2)cc1)c1ccc(N2CCOCC2)nc1 +Cc1ccoc1-c1nnc(Cc2cc(C3OC(CO)C(O)C(O)C3O)ccc2Cl)s1 +COc1cc(CNC2CCCC2)cc2[nH]c(=O)c3c(c12)NCCC3 +CCCCCCCCCCCCC(C)OC(=O)C(C(=O)Nc1c(OC)cc(OC)cc1OC)c1ccccc1 +CCOCCOc1cc2c(ccn2C(=O)NC)cc1Oc1ccnc(NC(=O)c2ccc(C3CCN(CC(C)O)CC3)cc2)c1 +CN1CCc2c([nH]c3ccc(Cl)cc23)C1c1cccc(O)c1 +Cc1ccc(C(=O)NCC(=O)O)cc1-c1ccc2c(C)cc(Oc3ccc(C(=N)N)cc3)nc2c1 +COc1ccccc1Oc1cc(N2CCC(Oc3ncc(F)c(N)n3)CC2)ncn1 +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)C1CCCCC1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4(CCCOC4)C3)n2)cc1OC(F)F +O=C(Nc1cn(CC=CCN2CCOCC2)nc1-c1cc(Cl)ccc1OC(F)F)c1cnn2cccnc12 +Oc1nc(-c2cc(-c3ccon3)n(Cc3ccccc3)n2)ncc1F +COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc3cc[nH]c3c2)n1 +O=C(NCc1nnn[nH]1)C1NC2(CCCCC2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(Cl)c1F +O=S(=O)(Nc1nccs1)c1ccc(Oc2cc(C(F)(F)F)nn2-c2ccccc2F)c(F)c1 +Cc1c(N(Cc2cccc(OC(F)(F)F)c2)S(=O)(=O)C2CC2)sc2ccccc12 +Cc1ccc2occ(CNCc3ccc(S(N)(=O)=O)cc3)c(=O)c2c1 +Cc1n[nH]cc1NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +Cc1ccn(-c2ccc(N3CCC(c4noc5ccc(F)cc45)CC3)nn2)n1 +CC(C)S(=O)(=O)c1ccc2c(c1)nc(CC(C)(C)C)n2CC1CC1 +O=C(NNc1ccc(N(CCCl)CCCl)cc1)Nc1cc(-c2ccccc2F)nc2ccc(N3CCCC3)cc12 +CCCC(=O)Nc1ccc(-c2ccc(N3CCN(C)CC3)c(NC(=O)c3cc(N)c(F)c(C)c3Cl)c2)cc1 +CCOC(=O)CCCCOc1ccc2c(=O)c(-c3ccc(O)cc3)coc2c1 +O=C(CCC(=O)c1cccs1)Nc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +O=C(c1ccc(F)cc1)C1CCN(C2CN(Cc3ccccc3)CCC2O)CC1 +NC(CCCCNC(=O)OCc1ccccc1)C(=O)N1CCSC1 +O=C(Nc1cncc(F)c1)N1CC2(CCN(Cc3cccc(Oc4ccc(Cl)cc4)c3)CC2)C1 +Cc1cc2nc(C(C)CNC(=O)c3ccc(-n4cnnc4)cc3Cl)[nH]c2cc1C +O=C(Nc1ccc(Cl)nc1)Nc1ccc(C2CNCCO2)cc1Br +CCNCCN(Cc1ccc(-c2ccc(Cl)cc2)cc1)C(=O)Cn1cc(Cc2cnn(C)c2)c(=O)nc1SCc1ccc(F)cc1 +CCC(C)C(N=C(S)Nc1cccc2ccccc12)C(=O)NC(C=O)Cc1c[nH]c2ccccc12 +COc1ccc(Sc2cc3ccccc3[n+](CCCCCC3CCCCC3)c2)cc1 +O=C(OC1CCCCC1)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CC(=O)N1CCN(c2ccc(CN(CC(F)(F)F)S(=O)(=O)Cc3ccccc3)cc2)CC1 +Cn1c(-c2ccccc2)nc2c(N)nc(C#CC3(O)CCCCC3)nc21 +COC(=O)N1CCC(c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)CC1 +Cc1noc(C)c1C(=O)NCC1CN(c2ccc(CNC(=O)c3ccc(Cl)s3)cc2)C(=O)O1 +O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1ccc(Br)s1 +Cc1c(Cc2ccc(=O)n(CCCC(F)(F)F)n2)c2cc(F)ccc2n1CC(=O)O +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(CNCc2ccccc2)cc1 +OCC1CCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)C1 +Oc1ccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)cc1 +O=C(c1ccc(-c2cnn3cccnc23)cc1)N(c1ncccc1Cl)C1CCCNC1 +CCCCc1ccc(CN(CCc2ccc(CC(=O)O)cc2)S(C)(=O)=O)cc1 +COc1ccc(F)c(-c2ccc(COc3cccc(C(CC(=O)O)C4CCC4)c3)cc2C(C)(C)C)c1 +Cc1cnc2ccccc2c1Nc1ccc(N2CCN(C)C(C)(C)C2)cc1 +N=C(N)SCCOc1ccc(C2CCC(O)(CC(=O)O)CC2)cc1 +CC1CCc2cccc(NC(=O)Nc3ccc(Cl)c(C(F)(F)F)c3)c2C1 +O=C(O)Cn1c(SCc2cccc(Cl)c2)nc2ccccc21 +Nc1ncc(C2CCC(O)CC2)nc1-c1ccc(C(=O)NC(CO)c2cccc(C(F)(F)F)c2)c(F)c1 +CC(=O)NC1CCN(c2ncnc3ccc(C#CCNC(=O)c4cccn(Cc5ccc(F)c(F)c5)c4=O)cc23)C1 +Cn1cc(CCCCN2CCC3(CC2)OCc2ccccc23)c2ccccc21 +CC(C)CC(C(=O)NCC(=O)CNS(=O)(=O)c1ccccn1)c1cccc(-c2ccccc2)c1 +O=C(Nc1ccc(Oc2cccc3[nH]c(=O)[nH]c23)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C(O)c1ccc2c(c1)[nH]c(=O)c1ccccc12 +CC(C)CN(c1ccc(C(O)(C#Cc2cccnc2)C(F)(F)F)cc1)S(=O)(=O)c1ccccc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(NCc4ccccc4-n4cncn4)nc23)N1 +CC(Nc1ncc(F)c(N2C(=O)OCC2CF)n1)c1cnc(-c2ccc(Cl)cc2)s1 +CC(=O)c1csc(CNC(=O)C2C(C(=O)NCC3CCNCC3)C3C=CC2C32CC2)n1 +CCC(C)Nc1nc2ccc(-c3ocnc3-c3ccccc3F)cc2s1 +COCCCn1c(NC(=O)c2cccc(C#N)c2)nc2cc(C(=O)NCc3cccc(OC)c3)ccc21 +COc1ccc(F)cc1-c1c(F)cnc2[nH]c(C3=CCN(CC(=O)N4CC(O)C4)CC3)cc12 +CC(C)Oc1cccc(C(=O)C2CCCN(Cc3cnc(N4CCOCC4)s3)C2)c1 +Cc1cc(C)nc(C(=N)Nc2nc(-c3ccccn3)cc3ccccc23)n1 +COc1cc(S(=O)(=O)c2ccc(F)c(F)c2)cc2c3c(oc12)CCNC3 +CC1CC(C)CC(C)C(O)C(C#N)=CC=CCC(C2CCCC2C(=O)O)OC(=O)CC(O)C(C)C1 +O=C(NC1CCN(Cc2ccccc2)CC1)c1cc(-c2ccc(F)cc2)cc(-n2cnnn2)c1 +CC1c2c[nH]nc2-c2ccccc2N1S(=O)(=O)c1ccc(Cl)cc1 +COC(=O)C1C2CCC(CC1c1cc3ccccc3[nH]1)O2 +CCOc1ccc(-c2nc(NC(=O)C(C)N)sc2-c2cc(OC)c(OC)c(OC)c2)cc1 +CC(C)CNCc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2N)cc1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2=O)nc(N2CCOCC2)n1 +CC1(c2cc(NC(=O)c3ccccn3)ccc2F)N=C(N)OCC1(F)F +Cc1[nH]c(-c2ccccc2Oc2ccccc2)c2c1C(=O)CCC2 +CC(=O)NCC1CN(c2ccc(-c3ccc(Cn4ncnn4)cc3)c(F)c2)C(=O)O1 +CCC(C)(C)C(=O)Nc1cc(C)c(C)c(S(=O)(=O)N2CCSC2)c1 +Cc1c(Nc2cnc3[nH]cc(C(=O)NC(C)(C)C)c3n2)cnn1C +CCCCOC(=O)NC(CNC(=O)CC1CC(c2ccc(C(=N)N)cc2F)=NO1)C(=O)O +COCCOc1ccc2c(c1)C1(N=C(N)N(C)C1=O)C1(CCC(OC)CC1)C2 +CCNC(=O)Nc1cnc(Nc2ccc(OC(C)C)c(F)c2)n(Cc2ccc(Cl)cc2)c1=O +O=C(O)COc1ccc(Nc2ccc(CCNCC(O)c3cccc(Cl)c3)cc2)cc1 +CCCC(NC(=O)C(C#N)=Cc1cccc(C=C(C#N)C(=O)NC(CCC)c2ccccc2)c1)c1ccccc1 +COCCN1CCN(C(=O)c2sc3c([N+](=O)[O-])cc(C(F)(F)F)cc3[n+]2[O-])CC1 +CC1CN2CCN(Cc3cccnc3)CC2CC1(C)c1cccc(O)c1 +CCNC(=O)Nc1ccc2ncc(Nc3cccc(C)c3)nc2n1 +CCOC(=O)C1=CCCCC1S(=O)(=O)Cc1ccsc1 +CC(Oc1cc(-c2cnc3ccccn23)sc1C(N)=O)c1cc(CO)ccc1Cl +COc1cc(C(=O)N2CCOCC2)ccc1Nc1ncc(Br)c(OC)n1 +CCS(=O)(=O)c1ccc2cc1CNC(=O)C(Nc1ccc3c(N)nccc3c1)c1ccc(cc1)CCOC(=O)N2 +O=C(Cc1nnc(Cc2nc3ccc(-c4ccccc4)cc3s2)o1)NC1COC1 +CCCC(C)COc1ccc(C(CNCC(C)CC)NC(=O)C(C)c2ccccc2)cc1 +CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)cc4)nc3c2)ccn1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC3CCC3)n1)CCN2 +Cc1cc(-c2cccc(Oc3ccc4c(c3)c(=O)ncn4Cc3c(F)cc(F)cc3F)c2C(F)(F)F)cnc1N +O=C(NC1CCc2ccccc21)C(=O)c1c[nH]c2ccccc12 +CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc32)CC1 +CNCCC#Cc1cc(Cl)c(C2(C)CS(=O)(=O)C3(CCC3)C(=N)N2)s1 +CCN(CC)CCn1nc2c3c(c(NCCN4CCNCC4)ccc31)C(=O)c1ccccc1-2 +COCCNCc1cc(C2(C)CCSC(N)=N2)c(F)cc1F +O=C(O)c1ccc2c(c1)nc(-c1ccc(OC(c3ccc(Cl)cc3)c3ccc(Cl)cc3)cc1)n2C1CCCCC1 +[C-]#[N+]c1ccc(N2C(=O)C(C)(C)N(c3ccccc3C(=O)O)C2=S)cc1C(F)(F)F +COc1cc(Nc2ncc3ccn(-c4ccc(SC)cc4)c3n2)cc(OC)c1OC +CCCC(C)COc1ccc(C(CNCc2ccccn2)NC(=O)C(C)c2ccccc2)cc1 +CN(CC=Cc1cccc(C(F)(F)F)c1)Cc1ccc2c(c1)OCCC2 +COc1ccccc1CNC(=O)c1cn2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc2n1 +Cc1cccc(N2CCN(CC(O)COc3ccccc3C(=O)CCc3ccccc3)CC2)c1C +COc1cc(OC)c(C=CC(=O)C=Cc2ccc(N(C)C)cc2)c(OC)c1 +CCOc1cccc2cc(C(=O)N3N=C(c4cccnc4)CC3c3ccccc3O)oc12 +O=C(Nc1ccccc1)N(Cc1cc(Br)cc(Br)c1O)c1ccccc1Br +COc1ccc2cccc(C(CO)CNC(=O)C(F)F)c2c1 +CCCCCCCC#CC1(C(F)(F)F)CC(c2ccc(OC(F)F)cc2)=C(NC(=O)CS(C)(=O)=O)C(=O)N1 +COc1ccccc1Cn1cc2nc(-c3ccco3)nc(N)c2n1 +OCCn1cc(-c2cc(-c3cnn(CCO)c3)c3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +Cc1ccncc1-c1ccnn2c(-c3cc(Cl)cc(Cl)c3)cnc12 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2cccc(CC(F)(F)F)c2)c1)C(F)(F)F +COc1cc(OC)c2c(c1)OC(c1ccc(OC(=O)Nc3ccccc3)c(OC)c1)CC2=O +CC(=O)C1CCC2C3CCC4CC(O)(COCc5ccccc5)CCC4(C)C3CCC12C +CC1OC(=O)C2(N)CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4C#N)cn3)C12 +COc1cc2c(Oc3ccc(NC(=O)c4cc(-c5ccccc5)ccn4)cc3F)ccnc2cc1OCCCN1CCOCC1 +CNC(=O)C(Cc1ccccc1)NC(=O)Nc1n[nH]c(=S)s1 +COc1cc(C)c2cc1C(=O)NCCCOc1cccc(c1)Sc1cc-2nc(N)n1 +CCN(CC(CCN1CCC2(CC1)C[S+]([O-])c1ccccc12)c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccccc1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccc(C(F)(F)F)cc2[nH]1)C(F)(F)F +CC(Cc1ccc(OCP(=O)(O)c2ccccc2)cc1)NCC(O)COc1ccc(O)c(NS(C)(=O)=O)c1 +CCCCCCCCn1ncn(-c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)c1=O +CN1CCN(c2ccccc2C(=O)C=Cc2ccc(C=CC(=O)NO)cc2)CC1 +OC1(c2ccc(F)cc2)CCC(N2CCN(Cc3ccccc3)CC2)CC1 +CC(NC(=O)Nc1cc2[nH]nc(-c3cnn(C)c3)c2cn1)c1ccc(Cl)cc1 +COC(=O)C(C)(C)Cn1c(=O)cc(Nc2cccc(C(F)(F)F)c2)n(Cc2ccc(Cl)cc2)c1=O +CC(C)(C)c1cc(NC(=O)Nc2ccc(NC(=O)c3ccc(OC4CCNCC4)cn3)cc2)no1 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+O=C(O)COc1c(C(=O)O)sc(-c2cccc(NCC3CCN(C(=O)Nc4ccccc4Cl)CC3)c2)c1Br +N=C(CCl)NCCCC(NC(=O)c1ccccc1)C(N)=O +O=C(NCc1cnccn1)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +O=C1CN=C(c2ccccc2F)c2cc(Cl)c(Cl)cc2N1 +Cc1ccc(C(CNC(=O)c2ccc(C=Cc3ccccc3)cc2)n2ccnc2)cc1C +CCNCCNc1cc(-c2ccc(C(F)(F)F)cc2)c(C#N)c2nc3cc(Br)ccc3n12 +CC(C)S(=O)(=O)CCOC12COc3c(F)ccc(F)c3C1(S(=O)(=O)c1ccc(Cl)cc1)CCC(=O)C2 +CCN(CC)Cc1cccc(Nc2ccnc3cc(Cl)ccc23)c1O +O=C(C=NNc1c(Cl)cc(C(F)(F)F)cc1Cl)NCCCCCCCNc1ccnc2cc(Cl)ccc12 +COc1cc(-c2nc(-c3ccccc3)c(-c3ccc(O)cc3)[nH]2)cc(OC)c1O +CS(=O)(=O)Nc1ccc(-c2ccnc(Nc3ccc(CN4CCOCC4)cc3)n2)cc1 +CC(=O)NC(C)c1ccc(C#Cc2ccc(OC3CCC3)cc2)cc1 +CCCCCOc1ccc(NC(=S)NC(=O)c2cccnc2)cc1C(F)(F)F +O=S(=O)(Nc1cc(Sc2ncn[nH]2)c(O)c2ccccc12)c1ccc2ccccc2c1 +O=C(CNC(=O)c1cccc(C(F)(F)F)c1)NC1CCN(C2CCC(c3ccc(O)cc3)CC2)CC1 +NC(=S)NN=C(c1ccc(O)cc1)c1cccc(C(=O)c2ccc(O)cc2)c1 +N=C(N)c1ccc(-c2ccc(-c3ccc(C(=N)N)s3)s2)cc1 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3cccs3)nc21 +COC1CN(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4F)nc23)C1 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+CCOc1ccc(Oc2c(Cl)cnn(C3c4ccccc4-c4ccccc43)c2=O)cc1 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4cc(OCC(C)(C)CO)ccn4)n3)ccc2[nH]1 +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccc(Br)o2)[nH]c1=O +Cc1cccc(F)c1CN1CC(c2ccc(N3CCN(c4ccccn4)CC3)cc2)C(N(C)C)C1 +CCCCc1noc(-c2ccc(C(=O)NCC3CCCC3(C)C)cc2)n1 +COc1cc(OC)cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5ccnc(C)n5)ccc43)cc2F)c1 +CC(C)(C)c1cn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)nn1 +CCc1nc(-c2ccc(C(F)(F)F)cc2OC)c(CC)nc1NC(CC)CC +Cc1cc(C#N)cc(C)c1Oc1cc(Nc2ccc(C#N)cc2)[nH]c(=O)c1 +COc1ccc(C(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CN(C)CC4)c2)cc1OC +CC1(O)CCC2C1CC=C(C=O)C(CCC1C(C)(O)CCC3OC(C)(C)C(O)CCC31C)C2(C)C +Cc1nc(C)n(-c2cc(C3CC3c3nc4ccccc4n3C)nc(N(C)C)n2)n1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)cc1-c1csc2ccccc12 +CC(C)c1cccc(C(C)C)c1OC(=O)NC(=O)SCc1ccccc1 +COc1cc(Cl)c2c(c1)C1(CCCCC1)NC(=O)N2 +CCCN1CCC(N(C)C(=O)c2ccc(-n3c(C)nc4ccccc43)cc2)C1 +CCc1nn2c(-c3c(COC)cc(OC)cc3OC)cccc2c1N(CC1CCOCC1)CC1CC1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CC(C#N)C1 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+O=C(Nc1ccc(N(CCCl)CCCl)cc1)Nc1ccc2ncnc(Nc3cccc(Cl)c3F)c2c1 +O=C(NO)c1ncc(COCc2ccc(F)cc2)c(CO)c1O +CC(=O)NC(Cc1ccccc1)C(=O)NC(Cc1ccc(C2CC(=O)NS2(=O)=O)cc1)C(N)=O +CCOC(=O)c1ccc2cc(Oc3ccnc(C(=O)NC)c3)ccc2c1 +CC(=O)N(C1=C(N2CCCC2)C(=O)c2ccccc2C1=O)c1ccc(F)c(F)c1 +O=C(Nc1ccc(O)cc1)c1cnc2[nH]cc(-c3ccc(O)cc3)c2c1 +Cc1ccc(F)cc1-c1cc2cnc(NC(=O)C3CC3)cc2c[n+]1[O-] +CCC1(c2cccc(O)c2)CCCCN(CCCCCCCCCCCCN2CCCCC(CC)(c3cccc(O)c3)C2)C1 +CC(=O)Nc1cc(-c2ccc(-c3cc(NC(=O)c4ccnc(N5CCCC5)c4)ccc3C)cc2)[nH]n1 +Cn1c(Cc2nc3cc(C(N)=O)ccc3[nH]2)nc2ccc(C(=O)NC(CCCCCP(=O)(O)O)C(=O)O)cc21 +COC1C(F)CN(C(=O)Cn2nc(C(C)=O)c3cccnc32)C1C(=O)NC(C)c1cccc(Cl)c1F +C[S+]([O-])c1ccc(C2CN3CCCC3c3ccccc32)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cncnc32)cc1NC1CC1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2CCc1ccccc1 +O=C(c1ccc2c(c1)c1ccccc1n2CCCl)N1CCCCC1 +NCC1CCC(CNc2nc(NCCc3ccccc3)ncc2[N+](=O)[O-])CC1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1cccc(Cl)c1 +COc1ccc(Cl)c(OC)c1C1CC(F)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 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+O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(N4CCN(c5cc(C(F)(F)F)ccn5)CC4)nc23)N1 +O=C(O)CCCc1nc(-c2cn(Cc3cc(Br)c(Br)c(Br)c3)nn2)no1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 +CC(C)c1cc(-c2ccc(F)cc2)c(OCC(O)CC(O)CC(=O)O)c(C(C)C)c1 +COc1ccccc1N1CCN(Cc2cn3cc(C)cc(C#N)c3n2)CC1 +CS(=O)(=O)c1ccnc2c1c(Sc1ccc(Cl)cc1)c1n2CCCC1CC(=O)O +O=C1NC(c2ccc(OCCCC(F)(F)F)cc2)(C(F)(F)F)CC(c2ccc3ccccc3c2)=C1c1nn[nH]n1 +CC(C)(C)Nc1nc2c(-c3cc4c([nH]3)CCNC4=O)cccc2nc1Cl +O=C(COc1ccccc1)N1CCCCC1c1nnn(-c2ccc3[nH]ccc3c2)n1 +CC(C)c1ccccc1OCCN1CCC(N(C)S(=O)(=O)c2cnn(C)c2)CC1 +O=C(Cc1ccccc1)NC1CCN(CC(=O)NC2CCc3cc(F)ccc3C2Cc2cccnc2)CC1 +N#CC(c1cccnc1)N1CCN(C(=O)C=C(c2ccccc2)c2ccccc2)CC1 +Cc1cc(N=c2[nH]c(=O)[nH]c(=O)n2Cc2ccc(Cl)cc2)ccc1OC(C)C +CC(C)CCn1c(=O)ccc2cnc(Nc3ccccc3)nc21 +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(N3CCNCC3)nc2c1 +O=C1c2ccccc2SC(c2ccc(Cl)cc2)N1CCCCNc1ccnc2cc(Cl)ccc12 +O=C(O)C(O)=CC(=O)c1cc(Cc2ccc(F)cc2F)cn(Cc2ccccc2)c1=O +COC1Nc2c(ccc(C)c2O)C(=O)N2C=C(C=CC(N)=O)CC12 +CC(C)c1ccccc1OCCNCCCCN1C(=O)C2CCCN2C1=O +CCC(CC)(NC(=O)c1cnn2c1NC(c1ccccc1)CC2(C)C)c1ccccc1 +OCCNc1nc(NCCc2ccccc2)c2cnn(C=Cc3ccccc3)c2n1 +Cc1c(C(C)c2c(F)cccc2F)nc(N2CCC(C)CC2)[nH]c1=O +CNC(=O)c1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccc4cnc(C)nc34)c2Cl)cc1 +C[n+]1c2n(c3ccccc31)N=C(c1ccccc1)CS2 +NCCCCN(Cc1nccc2c3ccccc3n(CCCN3CCNC(=O)C3)c12)C1CCCc2cccnc21 +Cn1cc(C=CC(=O)NS(=O)(=O)c2cc(F)c(F)cc2F)c2c(Oc3ccc4ncccc4c3)cccc21 +N=C(Nc1ccc(F)c(CSC2CCCC2)c1)c1cccs1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(OC4CCOCC4)c3Cl)C2)cc1 +CC(C)NC1CCC(n2cc(C(N)=O)c(Nc3ccc(S(=O)(=O)C(F)(F)F)cc3)n2)C(C#N)C1 +Cc1c2c(cc[n+]1Cc1ccccc1)c1ccc(OCc3ccccc3)cc1n2Cc1ccccc1 +CCCCOc1cc(C(=O)NC(CCC(=O)O)C(=O)N2CCN(C(=O)OC(C)C)CC2)nc(-c2ccccc2)c1 +COCN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +Cn1c(=O)c2c(CC(=O)Nc3nc(-c4ccc(C(F)(F)F)c(F)c4)cs3)nsc2n(C)c1=O +Cc1ccc2nc(N(C)C)nc(NCc3ccc(C(=O)NC4CCN(Cc5ccc(F)cc5)CC4)cc3)c2c1 +CCN(CC)c1ccc2cc(C(=O)NCC3NC(CO)C(O)C3O)c(=O)oc2c1 +CC(CCc1ccc(-c2ccc(NS(C)(=O)=O)cc2)cc1)(C(=O)NO)S(C)(=O)=O +COCCNc1cc(-c2ccccc2Cl)c(N(C)C(=O)C(C)(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cn1 +COc1ccccc1-n1nc2c(c1C(C)C)C(C)(c1ccc(Cl)cc1)N(c1ccc(F)c(Cl)c1)C2=O +NC1CCCC(NC(=O)c2ccc(O)c3[nH]c(C4CC5CCC4C5)nc23)C1 +CCc1nc(N)cc(OC)c1-c1ccc2c(c1)N(CCCOC)CCC2 +CNc1nc(Cl)nc2c1ncn2C1OC(C(=O)NCCC(c2ccccc2)c2ccccc2)C(O)C1O +O=C(NCCCN(C1=NS(=O)(=O)c2ccccc21)c1cccc(F)c1)c1ccc(F)cc1 +COc1ccc(C#Cc2cccc(C(=O)O)c2)cc1Cc1cnc(N)nc1N +COc1cc2c(cc1OC)C(c1ccc(Cl)cc1Cl)CN(Cc1cnc(N)nc1N)C2 +C[N+]1(CC2CC2)CCc2c(sc(NC(=O)Nc3ccc(Cl)cc3)c2C(N)=O)C1 +Cc1ccc(C(=O)NC2CCOCC2)c(F)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +C=C(c1c(C)c(C)cc(Cl)c1OCC(O)CNC(C)(C)C)n1ccnc1 +COc1cccc(C2(O)CCCCC2N2CCC3(CC2)C(=O)NCC3c2ccc(F)cc2)c1 +CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1C +Cc1csc(NC(=O)c2cc(Oc3ccccc3)cc(Oc3cccc(S(C)(=O)=O)c3)c2)n1 +CC(=O)OC1CCCC(NC(=O)Nc2cc3[nH]nc(-c4ccnc(C)c4)c3cn2)C1 +CCN(C)c1nccc(N2CCC(Oc3ccc(C(C)NC(=O)c4cn[nH]c4)cc3)C2)n1 +CC1(C)Cc2ccc(C#N)cc2C1NC(=O)c1cc2cc(Cl)ccc2[nH]1 +CCN(CC)c1nc(Nc2ccc(S(N)(=O)=O)cc2)nc(N(CC)CC)n1 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+CCNC(=O)c1ccc2nc(C)c3nnc(-c4cccnc4OC)n3c2c1 +C=Cc1csc2c(NCC(N)Cc3ccccc3)nc(-c3ccncc3)nc12 +O=C1OCCc2cc(C3CN4CCN(C(=O)Cc5cnc(-n6cnnn6)nc5)CC4CO3)ccc21 +COc1ccccc1COCCCOc1ccc(N2C(=O)CNCC2COCc2ccc(C)cc2)cc1 +CN1CCN(c2nc3ccccc3c3c2CN(C)CC3)CC1 +O=C(NO)c1cnc(NC23CC4CC(CC(C4)C2)C3)nc1 +N=C(NCCO)c1c(O)nsc1Nc1ccc(Nc2ccc(Br)cc2)cc1 +COc1cc(OCc2csc(N(C)CCO)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1C#Cc1ccc2ccc3cccc4ccc1c2c34 +CC(NC(=O)C(C)(F)F)c1ccc(OC2CCN(c3cccc(C(F)(F)F)n3)C2)cc1 +Cn1nccc1-c1cc(C(F)(F)F)ccc1N1CCOc2cc(S(=O)(=O)Nc3ncns3)ccc21 +Cc1nccn1-c1cc2nc(O)c(O)nc2cc1[N+](=O)[O-] +CC1CCCN1CCCOc1ccc(C(=O)CN2CCN(C(=O)c3cccn3C)CC2)cc1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1cccc2cccc(Cl)c12 +Cc1cc(NCC(N)c2cccs2)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +CN(C)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3CCc2ccccc2)cc1 +COc1cccc(NC(=O)c2ccc(-n3cccn3)c([N+](=O)[O-])c2)c1 +COc1ccc(-c2nc(COc3ccc4c(ccn4CC(=O)O)c3)sc2-c2ccc(C(F)(F)F)cc2)cc1 +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)Nc3ccc(F)cc3F)nc12 +[N-]=[N+]=Nc1ccc(COc2ccc(C(O)CCC(=O)O)cc2)cc1I +Cc1cccc(Nc2ccccc2C(=O)NCCC(=O)NCCCCCCCNc2c3c(nc4ccccc24)CCCC3)c1C +CNCCCOc1c(C)cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)cc1C +CCOC(=O)C=C1C2C3C=CC(CC3)C2C(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCOC(=O)c1cc(CCn2cnc3c2NC=NCC3O)c2c(c1Br)CCCC2 +Cc1cncc(C(=O)Nc2csc(CN3CCC(C(=O)NC(C)(C)C)CC3)c2)c1 +CS(=O)(=O)c1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +O=C(O)CCCCC=C(c1cccnc1)c1cccc2ccccc12 +Cn1nc(C(C)(C)C)c(C#N)c1-c1nc2nc(-c3ccccc3C(F)(F)F)cc(N3CCOCC3)c2[nH]1 +CC(O)c1cccc(-c2nnc(N3CCC(N4CCCCC4)CC3)s2)c1 +C=CC(=O)Nc1cccc(CN2C(=O)N(C)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4)nc32)c1 +O=C(c1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1F)N1CCn2cccc2C1 +CCCCCCCC1=CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 +CCc1nc2nc(C)cc(Nc3ccc(C(F)(F)F)cc3)n2n1 +C=C(c1ccc(N(C)C)cc1)c1cc(OC)c(OC)c(OC)c1 +CCCc1cc(-c2cccc(S(C)(=O)=O)c2)nc(C#N)n1 +O=C1CCc2ccc(OCCCCN3CCN(c4cccc5[nH]c(=O)oc45)CC3)cc2N1 +Cc1ccc(C2CC(c3cc(Cl)ccc3O)=NN2C(=O)c2ccco2)cc1 +O=C1NC2(CCCC2)CN(Cc2ccc3cc4c(cc3n2)CC2(C4)C(=O)Nc3ncccc32)C1c1ccccc1 +NC(=O)Nc1sc(C#Cc2ccccc2F)cc1C(N)=O +COc1ccc2c(c1)CCN1C(=O)C3CCCC(C21)N3S(=O)(=O)Nc1cc(F)c(F)cc1F +CC(Cc1cnc2nc(N)nc(N)c2c1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +CCCCc1c(C)[nH]c2c(-c3ccccc3)c(C)nn2c1=O +O=C(O)C(Cc1ccccc1)Oc1ccc(-c2ccc(-c3c(Cc4ccccc4)sc4ccccc34)cc2)cc1Br +COc1cc(O)c2c(=O)c(OC)c(-c3ccc(OC)c(OC)c3)oc2c1 +C=C(Br)CN1C2CCC1C(C(=O)OC)C(c1ccc(I)cc1)C2 +NC(C(=O)N1CCSC1)C1CCC(NC(=O)OCc2ccc3ccccc3c2)CC1 +COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCC1CCNCC1 +CCCCCC(O)C=CC1C(O)CC(=O)C1CCSCCCC(=O)O +CN1C2CCC1CC(N(c1ccccc1)c1ccc(C(=O)N3CCCC3)cc1)C2 +COc1cncc(NS(=O)(=O)c2ccccc2C(F)(F)F)c1 +CN(C)c1ccc(-c2nc3ncnc(N)c3c(-c3ccccc3)c2-c2ccccc2)cc1 +NC1CCC(Nc2ccn3ncc(-c4ccc5ccccc5c4)c3n2)CC1 +CCn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2c(c1)c(-c1cccc(Cl)c1)cc(=O)n2C +CN(C)CCOC(=O)N1CCC(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)C(C#N)C1 +Cc1c(COc2ccccc2-c2cccc(N3CCC4(C(=O)O)CC4C3)n2)ccc2c1CCN(C(C)c1ccccn1)C2 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+O=C1NC(=S)NC(=O)C1=NNc1ccc(S(=O)(=O)N2CCc3ccccc32)cc1 +CCC1(O)c2cc3n(c(=O)c2COC(=O)C1OC)Cc1cc2cc4c(cc2nc1-3)OCO4 +Nc1cccc(CN2C(=O)N(Cc3ccc4[nH]ncc4c3)C(Cc3ccccc3)C(O)C2CCc2ccccc2)c1 +CNc1cc2c(cn1)cc(-c1ccc(F)c(NC(=O)Nc3cc(C(C)(C)C)no3)c1)c(=O)n2C1CCOC1 +CCc1ncnc(-c2ccc(C(=O)N3CCCCC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +O=C(NC(c1cccnc1)C(F)(F)F)c1cc(OCC2CC2)c(Cl)cn1 +CN1CCN(C2CCC(c3ccc(OCCCN4CCCCC4)cc3)CC2)CC1 +O=C(Nc1ccc([N+](=O)[O-])cc1)c1cc(Cl)ccc1O +COC1=Nc2ccccc2C2=NC(CN3CCN(c4ccccc4Cl)CC3)CN12 +Cc1nc(NC(C)c2cccc(-c3ccnc(F)c3)c2)cc(-c2ccc3ncsc3c2)n1 +COc1ccc(-c2ccc3c(c2)CCc2nn(-c4ccccn4)c(O)c2-3)cc1 +O=C(O)CN1CCN(c2nc3cccc(F)c3n3cccc23)CC1 +Cc1ncccc1OCC1CN(CC(=O)N2c3ccccc3CC2C)CCO1 +CC1c2nnc(-c3cnccn3)n2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl +CCc1cc2c(C(N)=O)nn(CC(=O)N3CC(F)C(OC)C3C(=O)NCc3cccc(Cl)c3F)c2cn1 +Cc1cc(C)cc(NC(=O)CN2CCC(c3cccc[n+]3[O-])CC2)c1 +CN(C)c1ccc(-c2nc3ccc(OCCOCCOCCF)cc3s2)cn1 +O=C(NCCCCN1CCCC1)C1C(C(=O)NCCc2ccccn2)C2C=CC1C21CC1 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+CC(C)(C)c1ccc(C(=O)NC(=S)Nc2ccc(NC(=O)c3ccccc3Cl)c(N)c2)cc1 +Cc1ccc(-c2c3n(c(=O)c4ncccc24)CCCN(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C3=O)cc1 +CNC(=O)c1cccc2c(Nc3ccc(NS(C)(=O)=O)cc3N(C)C)c3cccc(OC)c3nc12 +O=C1N(CCN2CCCCCC2)CCN1c1cccc(C(F)(F)F)c1 +CC1=CC(=O)N(Cc2cccc(F)c2)S(=O)(=O)O1 +O=C(O)c1cccc(S(=O)(=O)C2CCc3ccccc3C2)c1 +O=C(O)c1cccc(C=Cc2ccc(OCc3c(-c4c(Cl)cccc4Cl)noc3C3CCC3)cc2Cl)c1 +CN(Cc1ccccc1)c1cccc2cc(S(=O)(=O)Nc3ncns3)ccc12 +CCc1c(CCN2CCC(C(=O)O)CC2)cccc1-c1nsc(-c2ccc(OC(C)C)c(Cl)c2)n1 +CCCS(=O)(=O)Nc1cc(F)c(C(=O)c2c[nH]c3ncc(Cl)cc23)c(F)c1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC(C)(C)c1ccccc1 +CCCOC(=O)N1CCC(C(=O)O)=C(Cc2cccc(OCCc3nc(-c4ccccc4)oc3C)c2)C1 +Nc1ccccc1NC(=O)c1ccc(CNCc2nc(-c3ccc([N+](=O)[O-])cc3)no2)cc1 +Cc1cc(-c2cccc(SCC(=O)Nc3ccc(-c4cnccn4)cn3)c2)ccn1 +COCCN1CCn2cc(-c3nc(Nc4ccnn4C)ncc3C)cc2C1=O +CCCCCCCCCCCCCCCCNC(CNC(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1 +Cc1nc(-c2cnccc2Nc2cccc3[nH]ncc23)c2nc[nH]c2n1 +N#Cc1ccccc1CN1CCN(C(=O)CC(N)Cc2cc(F)c(F)cc2F)CC1=O 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+CC(C)N1CCC(OC(=O)C(O)(c2ccccc2)c2ccccc2)CC1 +CC(C)C(S)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)NC(C(=O)O)C(C)C +Cc1cccc(N)c1C[S+]([O-])c1nc2ccccc2[nH]1 +Cc1ccc(Cn2cnc3c(N(C)C)nc(Cl)nc32)cc1 +CCOC(=O)N1CCC2C(CC3C(=O)OC(C)C3C2C=Cc2ccc(-c3ccccc3F)cn2)C1 +N#Cc1c(-c2ccc(Cl)cc2)cc(-c2ccco2)nc1N +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3CCCC3C(N)=O)cc2n1 +CNC(=O)c1ccc(-c2cc(-c3ccc(S(C)(=O)=O)cc3)cnc2N)cc1 +CC(C)(C)C1CCc2sc(-c3nnc(CCl)o3)cc2C1 +COc1ccc(CC(=O)O)cc1C1=NCC(=O)N(Cc2ccc(Cl)cc2)c2ccccc21 +COc1ccc(Nc2cc(-c3cccc(O)c3)nc(N3CCOCC3)n2)cn1 +c1ccc(-c2nnn[nH]2)c(-c2ccc(Cn3c4ccccc4c4ccccc43)cc2)c1 +Nc1cnc(-c2ccc(-c3ccccc3C(=O)N3CCCC(O)C3)cc2F)cn1 +CC(C)C(N)C(=O)Nc1cnc(NCCNc2ccc([N+](=O)[O-])c(N)n2)nc1-c1ccc(Cl)cc1Cl +Fc1cnc(Nc2ccc3cc[nH]c3c2)nc1Nc1ccc2cc[nH]c2c1 +Cc1[nH]cnc1CSCCNC(=N)NCCSCc1nc[nH]c1C +CC(C)(C)OC(=O)NC(Cc1ccc(F)cc1)C(=O)NN=Cc1ccc(O)c(O)c1O +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CNC(C)(C)CO3)cc12 +CN(CCN1CCCCC1)C(=O)N1CCC(C(=O)c2ccccc2)CC1 +CCOc1ccc(OCC2Cc3ccccc3CN2C(=O)c2cccc3ccccc23)cc1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4ccc(N5CCCCC5)nn4)ccn23)c1 +COc1ccc2c(CCCCN3C(C)CCCC3C)cccc2c1 +[C-]#[N+]C1CCCCC1n1cc(C(N)=O)c(Nc2ccccc2)n1 +COCC1(c2ccc(C)cc2)CC(c2ccccc2)=NN1C(=O)Nc1ccc(F)cc1 +CCOc1ncccc1-c1nc(C2CCN2C(=O)c2cc(OC)c(C)cc2-n2nccn2)no1 +c1ccc2nc(NC3=NCC4(CN5CCC4CC5)O3)ccc2c1 +O=c1c2cncnc2ncn1Cc1nc(CCc2ccc(Cl)cc2)no1 +Cc1c(CO)oc2cccc3c2c1cn3S(=O)(=O)c1cccc2ccccc12 +CCCCCCCOc1ccc(NC(=O)Oc2ccccc2F)cc1 +CNS(=O)(=O)c1cnc(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)c(C)c1 +CCN1C(=O)C(NC(=O)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)N=C(C2CC2)c2ccccc21 +COC1CCC2(CC1)Cc1ccc(-c3cncc(C(F)(F)F)c3)cc1C21N=C(N)N(C2CC2)C1=O +O=C(CCCN1C2CCC1c1c([nH]c3ccccc13)C2)c1ccccc1 +N#CCCc1c(-c2ccccc2)c(O)nc2cc(Cl)ccc12 +COc1cc(C)ccc1S(=O)(=O)NN1CCC(C)=C(CC(=O)NCc2ccc(C(=N)N)cc2)C1=O +CC12CCC3C(CCC4Cc5nc6nc7ccccc7n6cc5CC43C)C1CCC2O +CC(CCCCCNS(N)(=O)=O)C1CCC2C(=CC=C3CC(O)CC(O)C3)CCCC21C +Cc1ccc2c(-c3nnc(SCCN4CCc5cc6nc(C(F)(F)F)oc6c(Br)c5CC4)n3C)cccc2n1 +COC(=O)C(NC(=O)c1cc(-c2cc[nH]c2)nc2ccccc12)c1ccccc1 +Fc1ccc(C2CN(CCc3ccc(Cl)cc3)CCC2c2cc(-c3ccc(Cl)cc3)n[nH]2)cc1 +O=C(c1ccc(-c2nc(COc3ccc(-c4nnco4)cc3)no2)s1)C(F)(F)F +CCCOCC1CC2(C)C(O)CCC2C2CCc3cc(O)ccc3C12 +COc1ccc(N2CC=C(c3cccc(Cl)c3)C2=O)cc1OCCN1CCCCC1 +CCOc1ccc(-n2cnc3cc(CNc4ccc(CC)cc4)ccc32)cc1 +CN(C)c1ncc(S(=O)(=O)NC2CCN(C(Cc3cc4ccnc(N)c4cc3C(F)(F)F)C(=O)O)C2=O)s1 +O=C(C1CCCN1C(=O)CCCCN1CCN(c2ccccc2-c2ccccc2)CC1)N1CCCCC1 +CCc1cccc2c1NC(=O)C(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)N=C2c1cccc(C)c1 +CCc1cccc(NC(=O)Nc2ccc(-c3nsc4ncnc(N)c34)cc2)c1 +Cc1nnc2sc(C(=O)NC3CN(c4ccncc4Cl)C3)c(N)c2c1C +O=C(NCc1ccc(F)cc1F)c1c(NCCc2ccccc2)c2cccnc2n(O)c1=O +COc1ccc(NCc2cnc3nc(N)nc(N)c3c2)cc1OC +CCn1ncc2c(NC3CCOCC3)c(C(=O)NCc3ccccc3)cnc21 +CCN(Cc1cnc[nH]1)c1ccc(OC(F)(F)F)c(Cl)c1 +OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)c1ccc(-c2cccc(F)c2)cc1 +CCc1[nH]c2nc(Sc3cnc4nccnc4c3)nc(N3CCC(N)CC3)c2c1Cl +CCCCNC(=O)c1ccc2c(c1)nc(-c1cccc(Oc3ccccc3)c1)n2C(CCCNC(=N)N)C(N)=O +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)C(N)CO)CC2)cc1 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+O=C(NC1CCOCC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +NC12CC1CN(C(=O)c1cc(NC(=O)c3cc(-c4ncccc4F)c(Cl)cc3Cl)n(-c3ccccc3)n1)C2 +O=C(NO)c1ccc(-c2ccc(CNCCc3ccc(F)cc3)cn2)s1 +Cc1cc(NS(=O)(=O)c2ccc(NCc3coc4ccccc4c3=O)cc2)no1 +NC(=O)c1cc(-c2c[nH]c3ncccc23)cc(NC2CCC(O)CC2)n1 +Cc1nc(C(=O)Nc2ccc(Cl)cc2)sc1C1(C)CC(c2cccc([N+](=O)[O-])c2)=NO1 +CS(=O)(=O)Nc1cc(OCCNCc2cccs2)ccc1F +O=C(NCc1ccccc1)c1ccc(-c2cc(-c3cc4c([nH]3)CCNC4=O)ccn2)cc1 +COc1ccc(CC(=O)NC(=N)NC(CC(C)C)C(=O)NCc2cccc(-c3nnn[nH]3)c2)cc1OC +ON=C1c2ccccc2-c2ccc(OCCN3CCCC3)cc21 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccncc1)c1ccc(-c2ccc(O)c(F)c2)cc1F +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3cnc(C(F)(F)F)cn3)cs2)CO1 +Cc1cn(C2CN(CP(=O)(O)O)CC2O)c(=O)[nH]c1=O +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CO)cccc3nc2-1 +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCCCCC2)C1 +CN(C)CCc1c[nH]c(-c2cccc(C(F)(F)F)c2)n1 +NC(=O)C=Cc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2 +CC(C)(C)OC(=O)N1CC2CC1CC2Oc1ncnc(Nc2ccc(S(C)(=O)=O)cc2F)c1[N+](=O)[O-] +COc1ccc2c(c1)c(C1=C(Cl)CN(C)C1)cn2S(=O)(=O)c1ccccc1 +Cn1nccc1-c1ccc(F)cc1Oc1ccc(S(=O)(=O)Nc2nccs2)cc1C#N +CN(C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N(CCC(=O)NC1CCCCNC1=O)Cc1ccc(Cl)c(Cl)c1 +C#Cc1cnn2c(NCc3cccnc3)cc(-c3ccccc3)nc12 +Cc1cc(Nc2nc(N3CCC(N)CC3)nc3ccsc23)n[nH]1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ncc(OC(F)F)cc3Cl)cs2)CO1 +CC1(C(=O)NC(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)CC(c2cccs2)=NO1 +CC(C)N(C(=O)NC1CCC(CCN2CCN(c3nsc4ccccc34)CC2)CC1)C(C)C +Cc1c(NS(=O)(=O)c2ccc(CCCCC3CCN(C)CC3)cc2)c(CC(C)C)nn1C +O=C(O)C(Cc1ccccc1)CC(Cc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +COCCNc1ccc2[nH]c(-c3n[nH]c4ccc(OC(C)c5c(Cl)cncc5Cl)cc34)nc2c1 +COc1ccccc1Oc1c(NS(=O)(=O)CCc2ccccc2)nc(-c2ncccn2)nc1OCCOc1ncc(C(F)(F)F)cn1 +COc1cc(C=NNC(=O)C(OC)c2ccc(N3CCCS3(=O)=O)cc2)cc(OC)c1Br +Cc1ccnc(Oc2ccc(-c3cc4c(cc3F)ncc3nc(C)n(C5CCN(S(C)(=O)=O)CC5)c34)c(Cl)c2)n1 +COc1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OCC1CN(C(N)=NC#N)CCCO1 +O=C(Oc1cccc2c1C(=O)C=C(N1CC1)C2=O)c1ccco1 +CC(CC(=O)O)NC(=O)CN1CCCC(CCC2CCNCC2)C1=O +CC(=O)N1c2ccc(NC(=O)CCCCCCC(=O)NO)cc2C(NC(=O)OC(C)C)CC1C +COCCn1cc(Nc2cc(-n3ncc4cc(C#N)cnc43)ncc2C(=O)NCC(F)C(C)(C)O)cn1 +CCCCc1nnc([S+]([O-])Cc2ccccc2C(=O)OC)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2cnc(-c3ccc(F)cc3)o2)cc1 +CC(C)(C)CCn1nc(-c2cccs2)c(O)c(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)c1=O +Nc1ccc(-n2cc(COC3OC(CO)C(O)C(O)C3O)nn2)cc1 +O=C(Nc1ccc(F)c(F)c1)C(=O)c1c[nH]c2ccccc12 +Cc1cnc2c(c1)CCc1cc(Cl)ccc1C2=C1CCN(C(=O)Cc2ccncc2)CC1 +CS(=O)(=O)Nc1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)c(F)c2)cc1 +O=C(NCCc1c[nH]cn1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +COCCOc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C#N)cc4)CC3)c2cc1OCCOC +CCCOc1cc(=O)oc2cc(OCc3cccc(Br)c3)ccc12 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)Nc1cccc(C(F)(F)F)c1O +Cc1ccc(-c2nn(-c3nc(-c4cc5ccccc5oc4=O)cs3)cc2C=O)cc1 +CC12CCC(O)CC1CCC1C2CCC2(C)C(C=NOCCCN)CCC12O +Cc1ccccc1-c1ccc(C(=O)N2CCN(C(=O)c3ccc4cc[nH]c4c3)C(C)C2)cc1F +CCCc1c(O)c(CCCOc2ccccc2)cc2c1CC(CCc1ccccc1)O2 +CCCCN(C)C(=O)OC1=C(c2ccccc2)Oc2ccccc2-n2cccc21 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+N=C(N)NCCCCC1CC(C(=O)NCC(NS(=O)(=O)c2ccc(F)cc2)C(=O)O)=NO1 +O=C(CN1CCCN(C(=O)c2ccccc2)CC(NC(=O)c2nccc3ccccc23)C1=O)NC1CC(=O)OC1O +Cc1nsc(-c2c(NC(=O)C3=C(C(=O)O)CCC3)sc(C)c2C)n1 +Cc1ccc2cccc(-n3c(SCC(=O)Nc4ccc(S(N)(=O)=O)cc4Cl)nnc3C(F)(F)F)c2n1 +CCCCCn1c(-c2ccccc2)c(C(=O)NC23CC4CC(C)(CC(C)(C4)C2)C3)c(=O)c2ccccc21 +COc1ccc(C2=NN(C(=O)Nc3ccc(Cl)cc3)C(CCO)(c3cccnc3)C2)cc1 +Cc1cccc2c1N(C1CCN(S(=O)(=O)c3cccc4cccnc34)CC1)C(=O)OC2 +COc1cc(N(C)C)ccc1OCCOc1c(Br)cc(C=CC(=O)O)cc1OC +CC(=O)c1ccc(Oc2ccc(-c3ccc(-c4cccc(C#N)c4)n3CC(=O)NC(=N)N)cc2)cc1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1cc(CN2CCOCC2)on1 +COc1cc2c(N3CCN(C(S)=Nc4ccc(-c5ccccc5)nc4)CC3)ncnc2cc1OCCCN1CCCCC1 +CC(=CC(=O)NC(CC(C)C)C(=O)N1CC2CC2C1C(=O)NC(C)CCC(N)=O)c1ccc(OP(=O)(O)O)cc1 +CC(C)=CCc1cc(C(=O)Nc2cc3ccc(OCCCN4CCCC4)c(C)c3oc2=O)ccc1O +CC(Oc1cncc(N2CCNCC2)n1)c1cccc(F)c1 +CC(NP(=O)(COC1C=C(F)C(n2cnc3c(N)ncnc32)O1)Oc1ccccc1)C(=O)OC1CCC1 +Cc1ccc(-n2nccn2)c(CN2CCCN(c3ncc4ccccc4n3)CC2)c1 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+COc1ccc(S(=O)(=O)N2CCCN(C(=O)c3ccc(OC(F)(F)F)cc3)CC2C(=O)NO)cc1 +CC(C)Oc1ccc(C=C2C(=O)Nc3cc(Cl)ccc32)c(OC(C)C)c1 +CC1(COCc2ccc(-c3ccc(F)cc3)cc2)Cn2cc([N+](=O)[O-])nc2S1 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ncc(C3CC3)cn2)CC1c1cccc(F)c1 +CCCc1ccc(Cc2ccc3c(c2)C2(OC3)OC(CO)C(O)C(O)C2O)cc1 +Cc1ccc(NC(=O)c2ccc(C)c(NC(=O)C=Cc3cncnc3)c2)cc1F +N#CC1(CNc2cc(-c3ccnc4[nH]c(C5CCNCC5)cc34)c(Cl)cn2)CCOCC1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C(=O)NCCO +CCc1ccc(CN2CCCC(CNC(=O)c3cccc(OC)c3OC)C2)cc1 +C=CC(=O)Nc1ccccc1Nc1cc(N(C)C(=O)Nc2cc(OC)cc(OC)c2Cl)ncn1 +Cc1ccccc1C#CC1(O)CCC2C3OCC4=CC(=O)CCC4=C3C(c3ccc(N(C)C)cc3)CC21C +Cc1cccc(C(=O)NC(CC(C)C)C(=O)NCCN2CCc3ccccc32)c1 +COc1cnc2ccn(C(C)c3nnc4c(F)cc(-c5cnn(C)c5)cn34)c(=O)c2c1 +Cc1ccc(S(=O)(=O)NCCc2ccc(C(=CCCCC(=O)O)c3cccnc3)cc2)cc1 +CC1SC(N)=NC2(c3ccc(F)cc3F)COC(C3CC3)CC12 +CNC(=O)c1ccc(N2CCN(C(=O)c3ccccc3C(F)(F)F)CC2)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1Nc1cnn(C2CCOCC2)c1 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+COc1ccc(OC)c(C(=O)C=Cc2cn(-c3ccccc3)nc2-c2ccsc2)c1 +COc1c(F)cc2nc(-c3c(N)n[nH]c3C)sc2c1Cl +CCCSc1ncncc1C(=O)NC1C2CC3CC1CC(O)(C3)C2 +CCCCCCC1=C(c2ccccc2)C2(OCc3ccccc3)CCCC2C1 +Cc1cccc(Cl)c1CNC(=O)c1cn2cc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)ccc2n1 +O=C(C1CCOC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +Cc1cccc(CN2CCC(CCC(=O)c3ccc4c(c3)CCN4)CC2)c1 +Nc1cccc2c1CC(O)C(N1CCC(C(=O)c3ccc(F)cc3)CC1)C2 +COc1cc(F)ccc1-c1c(CN(C)Cc2ccccc2)[nH]c2c(NS(C)(=O)=O)cc(C(C)C)cc12 +Cn1cc(-c2ccc3nc(NC(=O)c4ccccc4)c(F)n3n2)c(-c2ccc(F)cc2)n1 +O=C(Oc1c(Br)cc(Br)cc1CNC(=O)c1ccccc1[N+](=O)[O-])c1ccccc1Cl +Cc1nnc(NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3-c3ccnn3C)c(C#N)c2)s1 +FC(F)(F)c1ccc2c(c1)c1cc[n+]2CCCCC[n+]2ccc(c3cc(C(F)(F)F)ccc32)NCCCCCN1 +O=C(O)c1cccc(C(CC(=O)c2ccc(Cl)cc2)CC(=O)c2ccc(Cl)cc2)c1 +C=CCC1(C)OC(S)=Nc2ccc(-c3cccc(Cl)c3)cc21 +O=C(O)C1CCN(c2cc3cccnc3c(-c3cccc(Cl)c3)n2)CC1 +CC1(C)CC=C(c2cc(C(C)(C)OCCN3CCCC3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCCC3)n2)cn1 +N#Cc1c[nH]c(C(=O)Nc2ccc(-c3cc[n+]([O-])cc3)cc2C2=CCCCC2)n1 +Cc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)C)n1)CCN2 +COc1ccc2occ(CSC(=S)N3CCCCC3)c(=O)c2c1 +NCCOc1c(-c2ccc(F)cc2)[nH]c(=O)c2cc(F)ccc12 +Nc1ncccc1-c1nc2ccc(-c3ccccc3)nc2n1-c1ccc(CNC(=O)c2ccccc2)cc1 +N#CCCNC(=O)C1=CC(C(F)(F)F)(C(F)(F)F)Oc2ccc([N+](=O)[O-])cc21 +Cc1ccc(Cn2sc(=O)n(Cc3ccc(F)cc3)c2=O)cc1 +CCC(C)C(NC(=O)C(NC(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccccc12)C(C)C)C(=O)OC +COc1cc(-c2cn(C3CC(C(C)(C)C)CCN(CC(F)(F)F)C3=O)nn2)ccc1-n1cnc(C)c1 +CC(=O)N1CCC(c2nc3c(C(N)=O)cccc3[nH]2)CC1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCc3ccccc3)cc2)cc1)C(=O)O +CC(CS)C(=O)N1C(SCc2ccc(C(C)C)cc2)CCC1C(=O)O +OC(CN1c2cccc(-c3cccc(OC(F)(F)F)c3)c2CCC1c1cccc(OC(F)(F)F)c1)C(F)(F)F +CNS(=O)(=O)c1cccc(Nc2cc(Nc3cccc(S(C)(=O)=O)c3)ncn2)c1 +CC1(CC(=O)NCc2cccc(I)c2)CC2(CCCCC2)OO1 +O=Cc1ccn(-c2cc3c(cc2Cl)nc(O)n2nc(C(=O)O)cc32)c1 +Fc1ccc(-c2[nH]c(-c3ccc(F)cc3)c3c2CCCC3)cc1 +Cc1c(Oc2ccc(C#N)cc2F)ncnc1N1C2CC3CC1CC(C2)N3C(=O)OC(C)(C)C 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+CC=CC=CC(=O)NC(CC(=O)NC(C(=O)C1C(=O)N(N(C)C)C(=O)C1C)C(C)C)c1ccccc1 +CC(C)C(CNO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +O=C(NCC1(N2CCOCC2)CCCCC1)c1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1 +Cc1ccc(NC(=O)Nc2ccc(S(=O)(=O)Nc3ccc(CC(C)(C)N)cc3)cc2)cc1 +CCCN(CCC)C1Cc2cc(F)c(O)cc2C1c1ccccc1 +COCCNC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CCCN1CCN(c2ccc3c(c2)C2CC3CCN2C(=O)OCc2ccccc2)CC1 +CNC(=O)c1nc(COC)ccc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +CCCN(CCC)CCc1ccc(O)c(OCCc2ccccc2)c1 +Cc1c(CCOCCO)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccccc1 +O=C(O)Cc1nn(CC(S)=Nc2cc(C(F)(F)F)ccc2Br)c(=O)c2ccccc12 +O=C1NC(=O)c2c1c1c3cc(F)ccc3[nH]c1c1c2c2cc(F)ccc2n1C1OC(CO)C(F)(F)C(O)C1O +CNC(=O)Cc1c(C)nc(CC(C)C)c(CN)c1-c1ccc(C)cc1 +CC(Nc1nccc(-n2cnc3ccccc32)n1)C1CN(S(C)(=O)=O)CCN1C +C=Cc1ccc(-c2ccc(C(=O)NCC(C)(C)C)cc2C(=O)O)c(C(=O)Nc2ccc3c(N)nccc3c2)n1 +COc1ccccc1-n1cc(C2=CCN(C(=O)OC(C)(C)C)CC2)nn1 +COc1ccc(-c2ssc(=S)c2-c2cc(OC)c(OC)c(OC)c2)cc1O +N#Cc1cc(NC(=O)NC2CCC(Oc3ccc(C(F)(F)F)cc3)CC2)cc(C(F)(F)F)c1 +Cc1ccc(C(=O)NCc2ccc(CNC(=O)C3CN(C)CCC3c3ccc(Cl)cc3)cc2)cc1 +Cc1c2ccnc(C(=O)NCCNCCO)c2cc2c3cc(O)ccc3n(C)c12 +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccncc3)sc12 +COc1cc(Br)nc(NC(=O)NS(=O)(=O)c2ccccc2C(=O)OCCO)n1 +COc1ccc(-n2c(Cn3ccnc3)cc3ccc(Cl)cc32)cc1 +CCOc1ccc(C(Nc2ccc(C(=N)N)cc2)C(=O)NCc2ccccc2)cc1OCC +C#CC1(CO)OC(n2cc(I)c(=O)[nH]c2=O)CC1O +Cc1cc(Br)c(Oc2nc(Cl)nc(Nc3ccc(C#N)cc3)n2)c(Br)c1 +Cc1c(Cl)nc(Cl)nc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +CCC(CC)C(=O)Nc1ccc(N2CCN(C(C(=O)N(CC)CC)c3ccc(Cl)cc3)CC2)c(F)c1 +O=C(Nc1c(C(O)(C(F)(F)F)C(F)(F)F)ccc2ccccc12)c1ccc(Cl)c(Cl)c1 +COc1ccc(NC(=S)N2N=C(c3ccc(O)cc3O)CC2c2ccc(O)cc2)cc1 +Cc1cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)cc(C)c1OCCNS(C)(=O)=O +Cc1ccc2nc(-c3ccccc3)c(NCc3ccccc3)n2c1 +COc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccsc2)cc1 +NCCCCn1cc(-c2cccc(OCc3ccccc3)c2)c2c(N)ncnc21 +O=C(Cn1c(=O)n(-c2ccncn2)c2ccccc21)Nc1ccc2c(c1)CC1(C2)C(=O)Nc2ncccc21 +CN(CCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)CC(c1ccccc1)c1ccccc1 +Cc1ccc(CNC2=NC(=Cc3c[nH]c4ncccc34)C(=O)N2)cc1 +COCCN(CCOC)c1nc(C)nc2c(-c3ccc(Cl)cc3Cl)n(C)nc12 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCC3)[nH]c12 +CN1C(=N)NC(C)(c2sc3c(-c4ccc(-c5nccs5)cc4)cccc3c2F)CS1(=O)=O +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(N2CC(F)C2)CC1 +O=c1[nH]cnc2c(-n3cc(CCN4CCC(c5ccccc5)CC4)cn3)nccc12 +O=S(=O)(c1ccccc1)N(Cc1ccc(OC(F)(F)F)cc1)c1sc2ccccc2c1Br +O=C1NCC(c2ccccc2)C12CCN(C1CCCCC1(O)c1cccc(F)c1)CC2 +CCC(=O)N1CCC(c2ccc(OCc3ccsc3-c3cccc(-n4ncc(C(=O)O)c4C(F)(F)F)n3)cc2)CC1 +COc1ccc(Nc2ncc(NCc3ccccc3)cc2-c2nc(C)nc3[nH]cnc23)cn1 +CCOC(O)=C1C(COCC(C)(O)c2ccco2)=NC(C)=C(C(=O)OC)C1c1cccc(Cl)c1Cl +COCCn1cc(-c2cccnc2)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O +CCCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)CC(C)O3)cc1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(Nc4ccc(NC5CCCNC5)nc4)c3c2)cc(Cl)c1O +CN1CCC2c3ccccc3-c3c(C4CCCCC4)c4ccc(C(=O)O)cc4n3CC21 +CCC(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(Cl)s1 +Cc1c(Nc2ccc(I)cc2F)c2c(=O)n(CC(O)CO)cnc2n(C)c1=O 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+O=C(O)c1cc(C2CC2)ccc1Nc1cnc(-c2cc(F)ccc2F)nc1 +CNC(=O)c1ccc(C(Cc2ccccc2)NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)cc1 +CCOC(=O)c1cc(C#N)c(N2CCN(C(=O)NCc3ccccc3C)CC2)nc1C(F)(F)F +CCN(CC)CCCNC(=O)CCc1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)[nH]n3)n2)cc1 +O=C1C=C(Oc2ccc(F)cc2Br)C(=O)c2cc3ccccc3cc21 +Oc1cc(F)cc(-c2nc(N3CCOCC3)c3oc4ncccc4c3n2)c1 +Cc1c(C(=O)Nc2ccc(Cl)cc2)c2ccccn2c1C(=O)c1ccc([N+](=O)[O-])cc1 +CCC(=O)OC1c2c(cc(OC)c3c(=O)c4cc5ccccc5cc4n(C)c23)OC(C)(C)C1OC(=O)CC +C(#Cc1ccc(-c2ccc(OCCCN3CCCCC3)cc2)cc1)CN1CCCCC1 +CC1CCCN1C(=O)c1cc(Nc2ncc3cnn(C4CC5CC5C4)c3n2)cn1C +O=C(O)CCC=CCC1COC(c2ccc(OCCCCCCOc3cc(C(=O)O)ccc3OCCn3ccnc3)cc2)OC1c1ccccc1O +CC1(O)CN(c2nc(C(C)(c3ccc(-c4cnc(N)nc4)cc3)C3CC3)no2)C1 +CC(C)N1CCc2ccc(C#Cc3ccc4c(Cl)c(CN)sc4c3)cc2C1 +CC(C)c1c(C=CC(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)cn1-c1ccccc1 +CCCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +COc1cc(OCc2cccc(OCc3ccc(F)cc3Cl)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=c1[nH]c(N2CCOCC2)nc(NC2CCCNC2)c1-c1nc2cc(C(F)(F)F)ccc2s1 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+O=c1c(C2=NS(=O)(=O)c3ccccc3N2)c(O)c2ccccc2n1CC1CCCCC1 +N#Cc1ccc(Cn2cncc2CNC2CCN(C(=O)c3cncc(Br)c3)C2=O)cc1 +O=C(NC12CC3CC(CC(C3)C1)C2)NS(=O)(=O)c1cnccc1NC1CC2CCC1C2 +CCC(=O)NC(Cc1cccc(-c2nccs2)c1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1B(O)O +Nc1ccc(C(=O)NC(Cc2ccccc2)CC(O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)cc1O +CN(C)C(=O)CN1CCC(c2ccc(Nc3nc4c(-c5cnn(-c6ccc(F)cc6)c5)cccn4n3)cc2)CC1 +CC1CN(Cc2cn3cc(-c4cnc(N)nc4)nc(N4CCOCC4)c3n2)CCN1S(C)(=O)=O +COc1ccc(-c2ccc3c(c2)CC2CNCC3C2)cc1 +O=C(Cc1cccc(C(=O)NC2CCCc3cc(CN4CCCCC4)ccc32)c1)c1ccccc1 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCn3ccc4ccc(Cl)nc43)c2)c1 +Cc1cccc(CNCC(C)C(=O)N(Cc2cc(Cl)c3c(c2)CCCCO3)CC(C)C)c1C +COc1cccc(CNC(=O)Nc2ccc(C3=NC=NC4NC=CC34)cc2)c1 +CCC1(c2cccc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCOCC1 +Fc1ccc(Cn2c(C3CCCN(Cc4ncco4)C3)nc3ccccc32)cc1 +O=C(NCCCCCCCCCCNC(=O)Nc1ccc(C2=NCCCN2)cc1)Nc1ccc(C2=NCCCN2)cc1 +O=C(NC1CNC1=O)OCc1ccc(C2CCCCC2)cc1 +COc1ccc(C(=O)C=Cc2ccc(C(=O)O)cc2)cc1[N+](=O)[O-] 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+O=C(CCCCc1cn(Cc2ccc(F)c(Cl)c2)nn1)NO +Cc1ccc(CCC(=O)Nc2ncc(Cc3cccc(Cl)c3Cl)s2)o1 +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc(OCCCn4cccc4)c4[nH]nc(N)c34)cc2)c1 +CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1ccc(OC)cc1 +CC(OCC1(c2ccccc2)CC(N)(C(=O)N(C)C)C1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCC(O)(c1ccccc1)N1CCC(NC(=O)c2cccc3ccccc23)CC1 +O=C(O)COc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)NCCCCC2CCCCC2)co1 +CCC(CC)OC1C=C(C(=O)Nc2ccccc2OC)CC(NC(=O)OC(C)(C)C)C1NC(C)=O +CC(c1cccc2ccccc12)C(CS)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +Cc1nn(C(F)F)cc1-c1cnc(N)c(-c2ccc(C(=O)NC(CO)c3cccc(CF)c3)c(F)c2)c1 +COC(=O)c1sc2ncnc(Nc3ccc(F)cc3OC(CN)CN)c2c1C +O=C(Nc1ccc(O)c(Cl)c1)C1CCN(CC(=O)N2CCN(c3nc4ccccc4s3)CC2)C1 +Nc1ncnn2c(C3CCC(CNCCO)CC3)nc(-c3ccc(Oc4ccccc4)cc3)c12 +COc1c(-c2cnn(C)c2)ccc2cnc(Nc3ccc(-n4cnc(N5CCOCC5)n4)cc3)nc12 +CCOC(=O)N1CCC(N2CCC2C(=O)N2CC(Sc3cccc(C(F)(F)F)c3)CC2C(=O)NC2(C#N)CC2)CC1 +O=C(NCC(CC1(C(F)(F)F)CC1)c1ccc(C(F)(F)F)nc1)c1ccccc1Cl +O=C(Nc1ccnc(O)c1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COc1ccc(C2(C#N)CC3CC(C(=O)NO)CC3C2)cc1OC(C)C +NC(=O)c1ccc(CCc2c(C(=O)O)[nH]c(=O)[nH]c2=O)cc1 +C=CC(=O)Nc1cc(Nc2n[nH]c3ccc(-c4ccc5ccccc5c4)cc23)c(OC)cc1N(C)CCN(C)C +OCC1OC(c2ccc(Cl)c(Cc3ccc(OC4CCOC4)cc3)c2)C(O)C(O)C1O +CC(c1ccccc1)c1nc(-c2cnc(N)c(-n3nnc4ccccc43)n2)nn1C +O=C(Cc1ccc(-c2ccccc2)cc1)NCc1ccccc1 +O=C1C2CC(O)(COCC(F)(F)F)CC2CN1c1ccc(OC(F)(F)F)cc1 +COCCNC(CN1CCC2(CC1)CCN(C1=C(C)C(=O)OC1)C2=O)c1ccc2c(c1C)COC2=O +O=C(Nc1ccc2nc(C3CC3)cn2c1)c1ccc(-c2ccccn2)cc1 +O=c1c2nn(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)c2cnn1CC(F)(F)F +CCc1cc2cc(-c3c(Cl)nc(N)nc3NC3CC(CO)C(O)C3O)oc2c(CC)n1 +Cc1nc(N2CCC(N3CCCC3=O)CC2)nc2ccc(NC(=O)C=Cc3ccc(Cl)cc3)cc12 +COC(=O)c1ccc(CSc2nc(Cc3c(F)cccc3F)c(C)c(=O)[nH]2)cc1 +Brc1cccc(C=NNc2nc3ccccc3nc2Cc2ccccc2)c1 +Cc1cc(N)c2cc(NC(=O)c3ccccc3COc3ccc([N+](=O)[O-])cc3)ccc2n1 +O=C(Nc1cc(-c2ccccc2)ccc1N1CCNCC1)c1cc2ccccc2oc1=O +CCCC(=O)Nc1n[nH]c2c(F)c(Cl)c(-c3ccccc3)cc12 +CCNc1nc2c(C)c(C)c(O)c(Cc3cccnc3)c2s1 +COC1C=CC(C)C2OC(O)(C(C)C(=O)OC(c3ccccc3)CCCCC1OC)C(OC)C(O)C2C +O=C1c2c(ccc3ccccc23)CN1CCCCN1CCN(c2cccc(Cl)c2Cl)CC1 +O=C(Cc1cc(Br)cc(Br)c1OCc1c(Cl)cccc1Cl)Nc1ccccc1[N+](=O)[O-] +CCn1c2cc(Cl)c(O)cc2c(=O)c2c(=O)o[nH]c21 +CCCCC1(CC)CS(=O)(=O)c2cc(CNC(CCS(C)(=O)=O)C(=O)O)c(OC)cc2C(c2ccccc2)N1 +COc1cc(C(=O)NC2CCN(C)CC2OC)c(F)cc1Nc1ncc(Cl)c(Oc2cccc3c2C(=O)N(C)C3C)n1 +c1ccc2c(NC3CCCCCC3)nc(N3CCC(N4CCCC4)CC3)nc2c1 +NC(=O)c1ccc(-c2ccc(Cl)cc2COc2ccc(-c3nc4cc(C(=O)O)ccc4n3C3CCCCC3)cc2)cc1 +COc1n[nH]c2cc(NC(=O)NCc3c(F)cccc3Cl)ncc12 +CCNC(=O)C1OC(n2cnc3c(NCC)nc(C#CC(O)C4CCCC4)nc32)C(O)C1O +O=C(NC1CCOCC1C(=O)NO)c1ccc(Cc2c(C3CC3)nc3ccccn23)cc1 +COc1ccc(-c2ccc(Cl)c(C(=O)NCC3(O)CCCCCC3)c2)nc1 +O=C(c1ccc(Oc2nccnc2N2CCC(O)CC2)cc1)c1nc2ccccc2[nH]1 +COc1ccc(-n2nc(CCC(=O)N(C)O)cc2-c2ccc(Cl)cc2)cc1 +COc1ccc(C(=O)NC2N=C(c3ccccc3)c3cc(C)cc4c3N(CC4)C2=O)c(OC)c1 +COc1ccc(S(=O)(=O)N(CC(=O)NO)OCc2ccc(Cl)cc2)cc1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)NCC3CNC(=O)C3)[nH]c12 +Cn1c(=O)c2cc(Cl)ccc2n2cnc(C(=O)OC(C)(C)C)c12 +NC(=O)C12CC3CC(C1)C(NC(=O)c1cccc(NS(=O)(=O)c4cccc(F)c4)c1)C(C3)C2 +O=C(c1nccs1)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +Cc1c(C(=O)Nc2ccc(Oc3ccnc4cc(-c5cn(C)cn5)sc34)c(F)c2)cnn1-c1ccccc1 +CC(=O)N(O)CCC(n1cc(C(C)(C)C)nn1)P(=O)(O)O +N#Cc1cnc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)cn1 +CC(OC1CCC2NC1(c1ccccc1)CC2(F)c1nnn(C)n1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCc1cc(-c2noc(-c3ccc(CC(C)C)c(C)n3)n2)cc(C)c1OCC(O)CNC(=O)CO +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(CN5CCC(O)C5)cc4)c3)c(OCCCF)cc21 +COCCOCC(=O)N1CCC(CCCCNC(=O)N2Cc3ccncc3C2)CC1 +CC(=O)OC(CC1CCCC(CC(=O)c2ccccc2)N1C)c1ccccc1 +CC1CN(C(=O)c2cc3c(C(=O)C(=O)N(C)C)cn(C)c3cc2Cl)C(C)CN1Cc1ccc(F)cc1 +N#Cc1cccc(C23CCC(N(CCN4CCC(O)C4)C(=O)Nc4ccc(F)c(Cl)c4)CC2C3)c1 +O=C(O)Cc1nn(Cc2nc3cccc(C(F)(F)F)c3s2)c(=O)c2ccccc12 +CC1(C)C2CCC1(CS(=O)(=O)Nc1cccc(S(N)(=O)=O)c1)C(=O)C2 +COC1(C(F)(F)F)CC(c2nc(-c3ccc(C)c(N(C)C(=O)c4cnc5ccccn45)c3)no2)C1 +O=C(Nc1ccncn1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +Cn1c(C2CCCCO2)nc(C(=O)NCc2ccc(F)cc2)c(O)c1=O +COCCN1CCC(Nc2nc(-c3nc4ccccc4n3Cc3ccc(F)c(F)c3)cn3c(C)nnc23)CC1 +O=C(CN1C(=O)Cc2c([nH]c3ccc(Br)cc23)-c2ccc(Cl)cc21)NCc1ccc(O)cc1 +CCCCNc1ncc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)c(NC2CCC(O)CC2)n1 +Cn1nc(CC(=O)Nc2ccc3oc4ccccc4c3c2)c2ccccc2c1=O +O=C(Nc1ccc(C(F)(F)F)cc1)N1Cc2ccccc2C1 +COc1cc(Sc2c[nH]c3ccc(OCCO)cc23)cc(OC)c1OC +CC(C)(C)NCC(O)CON=C1CC2CCC1(C)C2(C)C +CCC(C)(C)C(=O)C(=O)N1CCCC1C(=O)SCCCc1ccccc1 +Oc1cc(Nc2ccnc3cc(Cl)ccc23)ccc1CN1CCCCC1 +Cc1cc[n+](CCCCCCCC[n+]2ccc(C)cc2N)c(N)c1 +CCCCCCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(O)c2c1=O +COc1ccc(CCCN2CC=C(CCC(=O)NO)C2=O)cc1 +CCC(C)n1c2cnccc2c2cnc(Nc3ccc(N4CCNC(C)(C)C4)nn3)nc21 +Cc1ccc2nc(-c3ccc(OCc4ccccc4)cc3)c(NC3CCCCC3)n2c1 +CCCn1c(=O)c2nc(C34CCC(C=CC(=O)O)(CC3)CC4)[nH]c2n(CCC)c1=O +C=C1C(=O)OC2OC3(C)CCC4C(C)CCC1C24OO3 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCC(CO)C2)c(-c2cncc(F)c2)c1 +CCOC(=O)c1cn2ncnc(Nc3cc(C(=O)NOC)c(F)cc3F)c2c1C(C)C +OCc1cccc(-c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)c1 +COc1ccc2c(n1)CN(c1ncnn3c(C)nc(C4CCOC4)c13)CC2 +O=C(NCc1cccc(-c2ccc(F)c(CN3CCNCC3)c2)c1)c1ccc2c(c1)OCO2 +c1ccc(COCCCOc2ccc(C3CCNCC3OCc3ccc4ccccc4c3)cc2)cc1 +CCNC(=O)Nc1cccc(-c2cnc3cc(-c4ccnc(C(F)(F)F)n4)ccn23)c1 +Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(c3cccc(C(C)C)c3)C(C)C)cc12 +O=C(O)CCCCOc1cc(Cl)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +O=C1CCC(CCN2CC(N3CCNCC3)C2)(c2ccc(Cl)c(Cl)c2)CN1Cc1ccccc1 +O=S(=O)(c1cccs1)N1Cc2ccccc2N(Cc2c[nH]cn2)C(CCc2ccccc2)C1 +CCN(CC)Cc1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +O=C(CN1C(COc2ccccc2)C(O)C(O)C(COc2ccccc2)N(Cc2ccccc2)S1(=O)=O)Nc1nccs1 +COc1ccc(Nc2ccc3c(c2)C(=CNc2ccc(CN4CCCCC4)cc2)C(=O)NC3=O)cc1 +COc1ccc(NC(=O)Nc2cc(S(=O)(=O)N3CCCCC3)oc2C)cc1 +CC(NCC(O)c1ccc(O)c2[nH]c(=O)sc12)c1ccc2ccccc2c1 +COC1CCC(Nc2ccn3ncc(-c4cccc(OC(F)(F)F)c4)c3n2)CC1 +Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(F)c4Cl)cc3)cnc12 +CCOC(=O)N1CCN(CCCOc2ccc(C(=O)c3cccc(F)c3F)cc2)CC1 +CN1CCN(Cc2ccc(C(=O)NN(CC3CC=CC3)c3nc(C#N)ncc3Br)cc2)CC1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCC4CN(C)CCO4)ncc23)ccn1 +COc1cc(-c2cc(OC)c(-n3c(=O)ccc4cc(S(=O)(=O)Nc5cc(C)ncn5)ccc43)cc2F)ccc1F +C1=C(c2ccccc2)CCN(CCCCc2c[nH]c3ccccc23)C1 +Cc1ccccc1N1CCOc2cnc(NC3CCN(c4ccnc(Cl)c4)CC3)nc21 +Cc1cc(-c2nc(-c3ccc(OC4CC4)c(C)c3)n3c2CCOC(C)C3)cc(CF)n1 +NC(=O)C(Cc1ccccc1)NC(=O)CCCCCCC(=O)NO +NC(=O)c1cc2c(Oc3ccc(C(=O)N4CCOCC4)cc3)cncc2s1 +CCCCCN1CC2N(C(=O)OCCc3ccc(O)cc3)CCC(=O)N2C(Cc2ccccc2)C1=O +CCCN(Cc1ccc(F)cc1C(F)(F)F)C1CCNCC1 +CCc1ccc(OCCOCCOCCCCCNC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 +CCNC(=O)OCc1c(COC(=O)NCC)c(-c2ccc(F)c(F)c2)n2c1Cc1ccccc1C2 +O=c1nc(OCC2COCCO2)cc2n1CCc1cc(COC3CCCC3)ccc1-2 +CC1(c2ccc(C(=N)N)cc2)NC(=O)N(CC(=O)NC(CC(=O)O)C(=O)NC(C(=O)O)c2ccccc2)C1=O +Clc1cc(-c2ccnc(N3CCNCC3)c2)cc(Cl)c1OCc1ccccn1 +CCCCc1ncc(C(=O)O)n1Cc1ccc(-c2ccccc2-n2cnnn2)cc1 +COCCN(CC1CC1)c1nc(C)nc2c(-c3ccc(OC)nc3C)c(C)nn12 +CCCc1cc(=O)oc2cc(OCCCCN3CCC(c4noc5cc(F)ccc45)CC3)ccc12 +COc1cc(C(C)=O)ccc1OCCCN1CCC(C(c2cccc(F)c2)c2cccc(F)c2)CC1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCC2CCN(CC3CCOCC3)CC2)CCCC1)c1cc2ccccc2s1 +CCC(NC(=O)c1cc(C(=O)NCc2ncccn2)n2c1COCC2)c1ccccc1 +Cc1ccc(NC(=O)c2cc(NC(=O)c3cc(Cl)ccc3Cl)cc3[nH]c(N(C)C)nc23)cc1Cl +O=C(Nc1ccc2c(c1)C=CS(=O)(=O)O2)c1ccncc1 +CC(C)(O)CC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +COC1Oc2cc(F)ccc2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +COCCOc1cc2c(cc1OC)Nc1ncnc(Nc3cc(OC)c(Cl)cc3Cl)c1C2 +O=S(=O)(c1ccccc1)N1N=C(c2ccccc2O)CC1c1ccc(O)cc1 +O=C(C=Cc1cnccc1-c1cnn(CC(F)(F)F)c1)Nc1ccc(CN2CCOCC2)cc1 +CONC(=O)c1cc(Nc2ncnn3cc(-c4nnc(C(F)(F)F)o4)c(C(C)C)c23)c(F)cc1F +CC(C)CCCC(C)C1CCC2C3C(O)C=C4CC(O)CCC4(C)C3CCC12C +CCN(CC)C(=O)c1ccc(C(c2ccccc2)C2CCNCC2)cc1 +COc1c(C)cc(-c2c(-c3cccc(OC(F)(F)F)c3)cc3n2C(CCN)CNC3=O)cc1C +CCCc1cc2c(C(F)(F)F)cc(=O)[nH]c2cc1N +O=c1c(O)c(-c2ncc(Cc3ccc(F)cc3)[nH]2)nc2c(Br)cc(N3CCOCC3)cn12 +C=CCNC(=S)N1CCc2c([nH]c3ccccc23)C1C(F)(F)F +O=C(NCc1ccc(F)cc1)C1C(=O)N(O)C(=O)c2cc(F)ccc21 +CN(c1ccc(NC(=O)Nc2cccc(C(F)(F)F)c2)c(F)c1)c1cc(NC(=O)C2CC2)ncn1 +Cn1c(OCCOc2ccccc2)nc(-c2ccncc2)cc1=O +CCOc1c(F)cccc1C1CC(F)C(=O)N1Cc1ccc(OC(F)(F)F)cc1 +CC(=O)C1CCC2C3CCC4CC(O)(C#Cc5ccc(-c6ccccc6)cc5)CCC4(C)C3CCC12C 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+O=C(NCc1cccc(Cl)c1)Nc1cc(-c2ccccn2)n[nH]1 +CCCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1 +CCOC(=O)c1ccc(Oc2c[nH]nc2-c2ccc(OCC(=O)NN)cc2O)cc1 +CC(CCC(=O)O)(NC(=O)c1ccc(CCC2CNc3nc(N)nc(N)c3C2)cc1)C(=O)O +NC(=O)C1=c2ncnc(NCc3cccc(NC(=O)c4ccc(C(F)(F)F)cc4)c3)c2=CCC1 +c1ccc(COCCOCc2ccc(C3CCNCC3OCc3ccc4ccccc4c3)cc2)cc1 +CCCNC(=O)c1cnc(Nc2ccc(C#N)cc2)cc1Oc1c(C)cc(C)cc1C +CN(C)C(=Nc1cccc(C(=CCCCC(=O)O)c2cccnc2)c1)NC#N +Cc1ncnc(-c2ccc(C(=O)N3CCCO3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +O=C(NC(CC1CC1)c1nccs1)c1ccc(C2CCOCC2)c(OCC2CC2)n1 +N#Cc1ccc(OC(c2ccc(F)cc2)C2CCCNC2)cc1 +O=C(CCCCCCc1ccccc1)c1ncc(-c2ccccc2)o1 +NC(=O)C[S+]([O-])C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 +CS(=O)(=O)c1ccc(C2=CC(=O)c3ccccc3S2(=O)=O)cc1 +CSc1ccc(-c2sc(N)nc2-c2ccc(P(=O)(O)O)o2)cc1 +COCCOc1cc(NC(=O)N2c3nc(C=O)c(CN4CCN(C)CC4=O)cc3CCC2C)ncc1C#N +CC(Oc1ccccc1-c1cccc([N+](=O)[O-])c1)C1=NCCN1 +Cc1cccc(-n2cc3c(n2)c(N(C(=O)c2ccccc2)C(=O)c2ccccc2)nc2ccccc23)c1 +O=[N+]([O-])c1cccc(-c2ccccc2CCC2=NCCN2)c1 +O=C(c1ccn2c1CSC2c1cccnc1)c1c[nH]c2cccc(O)c12 +CN(c1ccc2c(c1)CCn1c-2cc(OCC2COCCO2)nc1=O)C1CCCCC1 +CCC1(CC)CC(NC(=O)Nc2ccc3c(c2)N(C)C(=O)CC3)c2ccc(Cl)c(Cl)c2O1 +CCc1cccc(CC)c1NC(=O)CC(N)C(Cc1ccccc1)NC(=O)C(NC(=O)CCCc1ccccc1)C(C)C +CCCC(O)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CCN)CC1 +CN1Cc2c(C3=CC4CNCC4C3)[nH]c3nccc(c23)-c2cc(F)ccc21 +COc1ccc(CCNCC(O)COc2cccc3[nH]ccc23)cc1OC +COC(=O)c1c(F)cccc1-c1ccc(CNc2ccc(C(=O)N3CCN(CC4CC4)CC3)cn2)c(F)c1 +O=C(NCC1CCNCC1)c1ccc(Cl)cc1-c1cccc(Cl)c1 +CC(c1nc2ccccc2o1)n1cc(C=CC(=O)NO)nn1 +Cc1nn(C)c2ncc(C(=O)NO)c(N(C)S(=O)(=O)c3ccc(Oc4ccc(Cl)cc4)cc3)c12 +Cc1nc(-c2ccc3occ(-c4ccc([S+](C)[O-])cc4)c3c2)no1 +Cc1nnc2c(NC(C)C)nc(-c3nc4ccccc4n3Cc3ccccn3)cn12 +Cc1nc(NCC(F)(F)F)nc(NC2CC(CO)C(O)C2O)c1-c1nc2cnccc2s1 +CNC(=O)N1CC=C(c2cc3c(-c4cc(F)c(F)cc4OC)ccnc3[nH]2)CC1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)NCc1nnnn1C +Cn1cnc2ccc(-c3cc(NCC(O)CN4CCc5ccccc5C4)ncn3)cc21 +O=c1c2c(oc(O)c1C(c1cccc(NS(=O)(=O)c3cccc(Cl)c3)c1)C1CC1)CCCCCC2 +OCC(NC1CCN(CCCc2c[nH]c3ccc(-n4cnnc4)cc23)CC1)c1ccccc1 +CC(C)n1ncc2c(C(=O)Nc3ccc(F)c(S(N)(=O)=O)c3)cc(-c3cccs3)nc21 +Cc1cc(C(=O)O)nn1Cc1ccccc1OCc1ccc(Cl)cc1Cl +CCCCCCCc1ccc(C(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +NC1CN(Cc2ccc(-n3cnnn3)cc2)CC1C(=O)N1CCCC1 +COc1ccc(N=C2c3cccc(Cl)c3C(=O)c3c(Cl)cccc32)cc1O +COC(=O)C=CC(=O)NC1CC23CCC1(OC)C1Oc4c(O)ccc5c4C12CCN(CC1CC1)C3C5 +O=C(c1ccccc1)N1CCC2(CCCN(c3ncc(-c4ccccc4)c(-c4ccc(Cl)cc4)n3)C2)CC1 +COCC(C)Oc1cc(C#Cc2ccc3[nH]ccc3c2)cc(C(=O)Nc2ccn(C)n2)c1 +Cn1c(SCc2ccccc2)nc(-c2ccccc2)c1-c1ccccc1 +Cc1ccc(C(=O)NC2CCC(CCN3CCC(c4cccc5c4CCO5)CC3)CC2)cn1 +FC(F)(F)c1nc(N2CCCCC2)c2[nH]c(-c3ccccc3)cc2n1 +COc1nc(NCCO)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +CN(CCOc1ccc2c(c1)C(Cc1ccc(Cl)c(Cl)c1)C(N)CC2)S(=O)(=O)CC1CC1 +CCOc1ccc2cc(-c3nn(CC4CCN(S(C)(=O)=O)CC4)c4ncnc(N)c34)ccc2c1 +Cc1cc(C#N)cc(Cl)c1Oc1nc(NC2CCN(c3cccc(C(N)=O)c3)CC2)ncc1Br +CC1=C(CCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)c2ccccc2C1=O +CC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)nc2c1Nc1ccc(CN2CCCC2)cc1 +c1ccc(CCCN2CCC3(CC2)OCc2ccccc23)cc1 +O=C(NCCOCc1ccccc1)n1c(=O)oc2ccccc21 +O=C1CCC(=O)NC(Cc2c[nH]c3ccccc23)C(=O)NC(Cc2ccccc2)C(=O)NC(CCc2ccccc2)CN1 +COc1cccc2cc(C(=O)C=Cc3cc[n+](Cc4ccccc4Cl)cc3)c(=O)oc12 +Nc1ccc(C#CCCN2CC=C(c3ccccc3)CC2)cn1 +c1ccc(N2CCN(CC3CCC(Nc4ncccn4)CC3)CC2)cc1 +CC(C)(C)CC(=O)Nc1ccc2c(c1)cc(C(=O)Nc1ccccc1)n2Cc1ccccc1C(F)(F)F +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC2CCC2)C(=O)C(O)CO)c1 +COC12CCC3(CC1C(O)CCC(C)C)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CN1C2CCC1CC(OC(c1ccc(Br)cc1)c1ccc(Br)cc1)C2 +CC(NC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CC(C)CC(NC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +COc1ccc(CC2Cc3c(ccc(O)c3O)C(CN)O2)cc1 +Cc1cn(Cc2ccccc2)cc1C(=O)NCc1c(C)cc(N)nc1C +CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2ccc(OC)nc2)c1 +Cc1cc(C)cc(-c2[nH]c3ccc(C(=O)N(C)C)cc3c2CCNCCCCc2ccncc2)c1 +CN(C)CCn1ccc2c1C(=O)c1cnccc1C2=NOCCO +Cc1cn(C2CC(N=[N+]=[N-])C(CO)O2)c(=O)n(CC2CC(CO)=NO2)c1=O +COC1Cc2sccc2C2(CCN(CCCCc3ccccc3)CC2)O1 +O=C(Cc1ccccc1)NC1CCN(C(c2cnccn2)c2ccc(F)cc2F)CC1 +CC1CC2CSC(N)=NC2(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CO1 +O=C(CNC12CC3CC(CC(C3)C1)C2)N1CCCC1B(O)O +COc1cc2c(c3c1c(=O)c1ccccc1n3C)CC(C1(C)CO1)O2 +CCOc1ccccc1-c1nc(O)c2nc3ccc(Br)c(C)n3c2n1 +Cc1ccc(C(=O)N2CC(C)OCC2Cc2cc(-c3ncccn3)ccc2F)c(-n2nccn2)c1C +Cc1ccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)cc1S(=O)(=O)N1CCOCC1 +c1ccc(CN2CCN(c3nc4ccccc4s3)CC2)cc1 +Cc1cc(OCCCON=C(N)N)cc(OS(=O)(=O)c2ccccc2S(C)(=O)=O)c1 +COc1ccc2nc3cc(Cl)ccc3c(Nc3ccc(N4CCCCC4)cc3)c2c1 +Cc1c(Cl)cccc1-n1nnnc1SCC(=O)Nc1ccccc1[N+](=O)[O-] +Nc1nc(-c2ccc(OCC3CCOC3)c(OC(F)(F)F)c2)c(Cl)c(=O)[nH]1 +CC(C)c1ccccc1-c1nc(NCc2ccc(-c3cccnc3)cc2)c2cccn2n1 +CC(C)(F)c1nccn1CC1CC(c2ccccc2)(c2ccccc2)C(=O)O1 +CCCCc1ncc(C(=O)OCC)c(NCc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)n1 +CCOP(=O)(OCC)C(=O)OCC1OC(n2ccc(NC(C)=O)nc2=O)CS1 +CCNc1cc(C(=O)NC(Cc2ccccc2)C(O)CNC2CCc3ccccc32)cc(N2CCCCS2(=O)=O)c1 +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)Nc3cccc(C(=O)O)c3)cc12 +Cn1c(=O)c2ccc(-c3cccnc3)cc2n2nc(-c3ccccc3)cc12 +NC(=O)c1ccc2c(c1)CCCN2c1ccc(CNC2Cc3ccc(F)cc3C2)cc1 +CCN(CCO)c1ncc(C(=O)Nc2ccc(SC(F)(F)F)cc2)cc1-c1cncc(F)c1 +COc1cc(NC(=O)C=Cc2cccnc2)ccc1-c1cnco1 +Cc1cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)cc(C)c1OCC(CO)CO +CN(Cc1nc2ccccc2n1CCC1CCCCN1)C1CCCc2cccnc21 +CC#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2C(C)C +N#Cc1ccc(C(c2cccnc2)N2CCC(NC(=O)c3nccs3)CC2)cc1 +COc1ccc(CNC(=O)c2nn(-c3ccc(F)cc3)c(OCC(O)CC(O)CC(=O)O)c2C(C)C)cc1 +C(COc1ccc(Cc2ccccc2)cc1)=NOC1CCCC1 +CCCCCCNC(=O)c1nc(-c2ccc(Cl)cc2)c(-c2ccc(Cl)cc2)n1C +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4ccc(SC)nc4)cc23)c1F +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(N4CCCC5(CCC(C(=O)NO)CC5)C4)ccc3OCC)nc12 +Cc1oc(-c2cccc(Br)c2)nc1CN(Cc1ccccc1)Cc1ccc(OC(C)(C)C(=O)O)cc1 +CCC(=C(c1ccccc1)c1ccc(O)cc1)c1ccccc1 +COc1ccc(-c2ccc(OCCCCN3CCc4cc(OC)c(OC)cc4C3)cc2)cc1 +CNC(=O)c1ccc(-n2cnc3c(NCC4CCOCC4)cc(Oc4ccc(O)c(F)c4)cc32)cc1C +CCN(CC)Cc1cc(Nc2cccc(C(=O)NC(Cc3ccccc3)C(O)CNC3CCCC3)c2)ccc1O +CC1(c2cc(NC(=O)c3ccc(Cl)cc3)ccc2F)CS(=O)(=O)C2(CCOC2)C(=N)N1 +COc1ccc2c(c1)C1C(CCN1CCN(C)C)Cn1c-2c(C2CCCCC2)c2ccc(C(=O)O)cc21 +CC1=C(CN2CC(C(=O)O)C2)CCc2cc(OCc3ccc(CC(C)C)cc3F)ccc21 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)O)cc3O)[nH]c2n(CCC)c1=O +NC(=O)c1cc(C(N)=O)n(-c2cccc(-c3cccc(OC(F)(F)F)c3F)c2)n1 +CNC(C)C(=O)NC(C(=O)N1c2ncccc2CC1CNS(C)(=O)=O)C(C)C +COc1ccc(F)c(-c2ccc(COc3cccc(C(CC(=O)O)C4CC4)c3)cc2C2=CCCC2(C)C)c1 +CCC(C)OC(=O)CCC(=O)Nc1nnc(S(N)(=O)=O)s1 +CC1SC(N)=NC2(c3ccc(F)cc3F)COC(c3ncco3)CC12 +CCCCCCCCCCCCOc1c(OC)cc(Nc2c(C#N)cnc3cc(OC)c(OC)cc23)cc1OC +Cc1c(-c2ccc(F)cc2)c(C=CC(O)CC(O)CC(=O)O)c(C(C)C)n1-c1ccccc1 +CC(C)c1onc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +CCc1ccc(N=C2NC(=O)C(=Cc3ccncc3)S2)cc1 +CN(C)CCn1nc2c3c(c(N(C)C)ccc31)C(=O)c1ccncc1-2 +Nc1nc(Nc2cccc(C(=O)O)c2)nn1C(=O)c1c(F)cccc1F +CCC1OC(c2ccc(Cl)c(Cc3ncc(-c4ccsc4)cn3)c2)C(O)C(O)C1O +C=CCN(CC=C)c1ccc(C=C(C#N)C(=O)O)c(OC)c1 +O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(c2[nH]cnc3ncnc2-3)CC1 +CN(C(=O)c1ccccc1)c1nc(-c2ccc(Br)cc2)cs1 +Clc1cccc(Nc2nccc(-n3cnc4ccccc43)n2)c1 +COc1ccc(C2c3[nH]c4ccccc4c3CC3C(=O)N(Cc4ccccc4)CN32)cc1 +CC1(C)OCc2c(Nc3n[nH]c(Cl)c3Cl)nc(-c3cn[nH]c3)nc21 +NC(=O)C1(NC(=O)c2cnc(N3CC(F)(F)C3)c(OCC3CC3)n2)CCCCC1 +CC(C)Oc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)c1ccc(N2CCCC2=O)cc1 +O=C(COc1ccc(C=NNC(=O)c2ccc(O)c(Cl)c2)c2ccccc12)Nc1ccc(Cl)cc1 +CC(C)(C)c1ccc(C(=O)Nc2ccc3sc(CN)nc3c2)cc1 +C#CCNC(=O)c1ccccc1Nc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 +CN1CCN(C(=O)CCCOc2cc(C(=O)N3CCCCc4sccc43)ccc2NC(=O)c2ccccc2-c2ccccc2)CC1 +CCN(CC)C(C)C(c1ccc2cc(OCC(C)(C)C(=O)O)ccc2c1)n1ccnc1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2ccccc2)C(O)CNC2(c3ccccc3)CC2)c1 +COc1ccc(-c2cccc(-c3ccc(O)cc3)n2)cc1OC +CN1CCN(c2ccc(C(=O)Nc3sc(Nc4ccc5ncccc5c4)nc3C(N)=O)cc2)CC1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc([N+](=O)[O-])cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2ncoc2c1 +CCN(CC)CCOc1ccc(-n2c3c(c4ccc(O)cc4c2=O)C(=O)c2cc(O)ccc2-3)cc1 +COc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCC1CN(C)CCO1 +COc1cc2c(cc1OC)-c1c(-c3cnc(CN4CCCOCC4)s3)ncn1CC2 +O=C1C(=O)N(Cc2ccnc(F)c2)c2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc21 +CN(C)CCn1cc(-c2ccc(F)c(C(F)(F)F)c2)nc1C1CCN(c2ncnc(N)c2Br)CC1 +CCNC(=O)Nc1ccc(-c2nc(N3CCOCC3)c3c(n2)C(C)(C)OC3=O)cc1 +Cc1c(C(=O)N(C)C2(C#N)CCOCC2)nn(-c2ccccc2Cl)c1-c1ccccc1 +CN1CCN(C(=O)c2cccc(Nc3c(Nc4ccccc4)c(=O)c3=O)c2O)CC1 +CN(C)S(=O)(=O)c1cccc(N2CCC(N(c3ccc(C#N)cc3)c3cccnc3)CC2)c1 +Cc1cccc(C)c1N1CC(CN2CCC(F)(F)C2)(C(=O)Nc2cc(C#N)cc(C(F)(F)F)c2)C(C)C1=O +O=S(=O)(c1ccc(Cl)s1)n1cc(C2CCCNC2)c2ccccc21 +COc1ccccc1Nc1nc(Nc2ccc(O)cc2)ncc1F +CNc1nc2c(N)ncnc2n1C1OC(COCc2ccccc2)C(O)C1O +Nc1ccc2c(c1)c(OCc1ccc3ccccc3c1)nn2CCN1CCCCC1 +CC1CN(CCCn2c3ccccc3c3ccccc32)CC(C)N1 +COc1ccc(CN2C(C(Cc3c[nH]c4ccccc34)NC(=O)C3CCCCC3)=NNC2CCc2ccccc2)cc1 +NC1(c2ccc(-c3nc4c(-c5cccc(F)c5)cccn4c3-c3ccccc3)cc2)CCC1 +Oc1ccc(-c2cnc3[nH]cc(-c4ccc(-c5nnn[nH]5)cc4)c3c2)cc1 +COc1ccc(N2CCN(CCCCc3c[nH]c4ccc(OC)cc34)CC2)cc1 +CCCCCCCCCCCCC(O)C1CCC(C(O)CCCCCCCCCCCCC2=CC(C)OC2=O)O1 +CC1(C)C2CC=C(CN3CCC(Nc4nc(-c5cc(C(F)(F)F)cc(C(F)(F)F)c5)ns4)CC3)C1C2 +O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cc(F)ccc3F)s2)nn1 +CCCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1scnc1C(=O)O +O=C1C(=O)c2cc([N+](=O)[O-])ccc2-c2ccccc21 +Cc1ncoc1-c1nnc(SCCCN2CCC3CC3(c3ccc(C(F)(F)F)cc3)CC2)n1C +NS(=O)(=O)c1ccc(NC(=O)c2c(-c3ccc(Cl)cc3Cl)noc2NC(=O)c2ccccc2)cc1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc(-c3ccccc3)cc2)nn1 +COc1cc(-c2ccc(OC(F)(F)F)cc2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +O=C(CS(=O)(=O)c1ccccc1)c1ccc(F)cc1 +Cn1cc(NC(=O)c2cc(NC(=O)c3cc(NC(=O)c4sccc4Cl)cn3C)cn2C)cc1C(=O)NCCCN1CCCCC1 +COC1C(F)CN(C(=O)Cn2nc(C(N)=O)c3ccncc32)C1C(=O)NC(C)c1cccc(Cl)c1F +Cc1cc(-c2ccc(N3C(=O)c4n[nH]c(C(C)(C)C)c4C3c3ccccc3OCCO)cc2)on1 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCC2CCCC3(C2)OCCO3)cc1F +Brc1c(Br)c(Br)c2[nH]c(NC3CCCNCC3)nc2c1Br +Cc1cccc(N2CCN(CCCNC(=O)c3cc(-c4ccccc4)n(N4CCCCC4)c3C)CC2)c1C +Cc1cc(NCC(N)c2ccncc2)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +CC1CCN(CCC2CCCN2S(=O)(=O)c2ccc3[nH]cnc3c2)CC1 +COc1ccc(OCCN(C)CCCN2C(=O)CSC2c2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)cc1 +Cc1cc(-c2ccc(CNC(=O)c3ccc4c(c3)C(F)(F)c3ccccc3-4)cc2)ccn1 +CN1CC=C(c2cn(C(=O)c3ccccc3)c3ccccc23)CC1 +O=C(Nc1ccc(-n2ncc3c(C(F)(F)F)cccc32)cc1)Nc1ccc(C(F)(F)F)cc1 +CCOc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCN(C(=O)OCC(C)C)CC3)s2)cc1 +COc1cc(C=Cc2ccc(-n3[se]c4cc(Cl)ccc4c3=O)cc2)cc(OC)c1 +Cc1cc(C(=O)Nc2ncc(-c3ccccc3S(N)(=O)=O)cn2)n(-c2ccc3cc(Cl)ccc3c2)n1 +CN(C)CCCn1cc(C2=C(c3csc4ccccc34)C(=O)NC2=O)c2ccccc21 +N#Cc1c2c3ccc(N4CCSCC4)c4cccc(c-2nc1=O)c43 +NC(=O)Cc1ccc2c(O)cc(-c3ccccc3)nc2n1 +COc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(N(C)C)c3ccccc32)cc1 +Cc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)O)cc3Cl)nc1-2 +CCCCCCCN(C)c1ccc(C(=O)Nc2cnc3ccccc3c2)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccno4)ncc23)ccn1 +CC(C)C(NC(=O)OCc1ccc(F)c(F)c1)C(=O)NC(CC(=O)O)C(=O)CF +COc1cc(F)ccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 +COc1n[nH]c2cc(NC(=O)NC(CO)c3ccccc3)nc(C)c12 +N#Cc1cc(-c2ccc(F)cc2)n(-c2ccc(S(N)(=O)=O)cc2)n1 +COc1ncc(-c2ccc3nc(NC(=O)NCCN4CCCC4)nn3c2)cc1NS(=O)(=O)c1ccc(F)cc1 +CC1(C)SC2C(NC(=O)Cc3ccccc3)C(=O)N2C1C(=O)O +CC(C)(O)Cc1ccc2c(c1)c1cc(OCC3CC3)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 +CCCCCCN(CCCCCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2ccc(Cl)cn12 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1ccc(C(F)(F)F)cc1 +OC1C(COC(S)=NC2CCCC2)OC(n2cnc3c(NC4CCOC4)ncnc32)C1O +Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1CNc1ccc(OCC(=O)O)cc1 +COc1cc2c(-c3cc(Br)ccc3O)nc3c(c(Cc4ccccc4)nn3-c3ccccc3)c2cc1OC +COc1ccc(Nc2nc3c(-c4ccc(S(C)(=O)=O)cc4)cccn3n2)cc1 +CN1CC=C(c2c[nH]c3ccc(-c4ccsc4)cc23)CC1 +Cn1nc(-c2ccccc2)c2ccc(OCc3ccccn3)nc21 +COc1ccc(C=C(C#N)c2cc(OC)c(OC)c(OC)c2)cc1Br +COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)Cc2ccccc2)C(C)C)C(C)C)ccc1OC +Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1CCOC1 +O=C(CN(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2cccc(Cl)c2Cl)CC1 +O=C(O)Cc1ccc(-c2noc(-c3ccccc3)c2C(=O)CCCOc2ccc(Cl)cc2Cl)c(Cl)c1 +COC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)cc3)ccn2)c1 +Cc1cccc(-c2ocnc2C(=O)Nc2c(C)nn(CCn3ccc4ccccc43)c2C)c1 +CC(O)C(=O)N1CCC(N(Cc2cc(Cl)ccc2Cl)c2ccc(C#N)c(Cl)c2)C1 +Cn1nc(NC(=O)c2ccccc2Cl)c(Br)c1C(=O)NCCC1CCN(c2ccncc2)CC1 +COc1ccc2c(CC(C)NCC(O)c3cccc(Cl)c3)c[nH]c2c1 +O=S(=O)(c1ccccc1)n1cc(C2CCNCC2)c2ccccc21 +COc1ccccc1N1CCN(CCCCN2C(=O)C3C4C=CC(C5C=CC54)C3C2=O)CC1 +Cc1cc(O)ccc1C1=C(c2ccc(O)cc2C)C2C(S(=O)(=O)Oc3ccccc3Cl)CC1[S+]2[O-] +Cc1cc(OCC(F)(F)F)cnc1C(=O)Nc1ccc(F)c(C2(C(F)F)N=C(N)OC3CC32)c1 +Cc1csc2c(=O)n(CCCn3cncc3C)c(=S)[nH]c12 +Cc1cc(-c2cnn(C)c2)cc(C2CCN(C(=O)c3cc(C4CC4)n[nH]3)C2)n1 +CN(CC(CCN1CCC2(CC1)C[S+]([O-])c1ccccc12)c1ccc(Cl)c(Cl)c1)S(=O)(=O)c1ccccc1 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CCN(c2ccccc2-c2cnccn2)CC1 +COc1ccc(C(=O)Nc2cnc3c(c2)CN(C)CC3(C)C)cc1Br +O=C(CSc1nnccc1-c1cccc2ccccc12)Nc1ccccc1Cl +O=C(O)CC1CCC(c2ccc(NC(=O)CCNC(=O)c3nc(-c4ccc(Cl)cc4Cl)oc3C(F)(F)F)cc2)CC1 +Cc1cc(C)cc(C(CC(C)C)NC(=O)c2cc(COc3ccc(F)c(F)c3)ccc2CCC(=O)O)c1 +O=C(Nc1cc(Nc2ccc3c(c2)OCc2ccccc2C3=O)ccc1F)c1ccccc1 +O=C(NCCCCC(=O)C(F)(F)F)c1nc(-c2nc3c(s2)CCCC3)sc1C1CC1 +CN1CCN(c2ccccc2-c2ccc(C(=O)Nc3ccc(Cl)cc3C(=O)Nc3ccc(Cl)cn3)cc2)CC1 +O=c1[nH]c(C2CCC(c3ccccc3)CC2)c(Cc2cccc(C(F)(F)F)n2)c(=O)[nH]1 +Cc1cc(N2CCCC2C(=O)NCCc2ccc3c(c2)OCO3)nc(-n2ccnc2)n1 +COc1cc(C=C2CCCN(Cc3cccc(F)c3)C2=O)ccc1-n1cnc(C)c1 +O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2occc21 +COCC(NC(=O)Nc1cc2[nH]nc(-c3ccc4nnn(C)c4c3)c2cn1)c1ccccc1 +Cn1c(CN2CCC(c3ccc(C(F)(F)F)cc3)CC2)nc2ccncc21 +O=C(NN(c1ccccc1)c1ccccc1)c1ccc([N+](=O)[O-])o1 +NC(=O)c1ccc(-c2nccc3c(-c4cncnc4)cccc23)cc1NC1CCC(O)CC1 +COc1ccc(S2=NS(=O)(=O)c3cc([N+](=O)[O-])ccc32)cc1 +NC(=O)c1cc(-c2ccc(F)cc2)c2ccc(CN3CCC(F)(F)C3)cc2n1 +Cn1nc(-c2cnc(N)c(-c3cnn(C(N)=O)c3)n2)nc1C1(c2ccccc2)CC1 +CC(C)(C)c1cc(NC(=O)C2CCN2c2ccc(C(F)(F)F)cn2)no1 +CC1CCC(=NNc2ccccc2)c2ncc(C(=O)O)c(=O)n21 +Cc1ccc(NC(=O)c2ccc(C3CCN(C)C3)cc2)cc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CC(=O)NC1C(O)C=C(C(=O)O)OC1C(O)C(O)Cn1cc(-c2ccc(-c3ccccc3)cc2)nn1 +N=C1NC(=O)C(=Cc2ccc(O)c(C(=O)O)c2)S1 +Cc1cccc(CC(NC(=O)c2ccccc2)C(=O)NC(C#N)COCc2cccc(C(=O)O)c2)c1 +C=Cc1ccc([Si](C)(C)COc2cccc(CN(CC)CC=CC#CC(C)(C)C)c2)cc1 +CCOc1c(Cl)cccc1OC(c1ccccc1)C1CNCCO1 +CC(Nc1nccc(N2C(=O)OCC2C(C)O)n1)c1nc(-c2cccc(C(C)(C)C)c2)no1 +CC(C)CC(NC(=O)c1cc(Cl)ccc1O)C(=O)NC(Cc1ccccc1)C(=O)NC(C=O)Cc1ccccc1 +NC1Cc2c(c(C(F)(F)F)nn2Cc2ccccc2)N(O)C1=O +CNCc1nc2cc(-c3c[nH]nc3C)sc2c(=O)[nH]1 +O=C1CCCC1CN1CCN(CCOC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +CN(C)CCNc1nc(Nc2ccc(CCNc3nc(NCCO)nc(Nc4cccc(N)c4)n3)cc2)nc(Nc2cccc(N)c2)n1 +CC1(c2cccc(NC(=O)c3ccc(C(N)=O)cn3)c2)CCSC(N)=N1 +COc1ccc(CC2c3cc(OC)c(OC)cc3CCN2CC(=O)NCc2ccccc2)cc1OC +CN(C)C(=O)CN1CCC(c2ccc(Nc3nc4c(-c5ccc(C#N)cc5)cccn4n3)cc2)CC1 +O=C(CCCCCC(NC(=O)C1CCC(=O)N1)C(=O)Nc1ccccc1)NO +COc1ccnc(OC)c1C1CC(C)C(=O)N1Cc1cccc(-c2nc(Cl)cs2)c1 +COc1ncc(C#N)cc1-c1ccc(C(C)NS(=O)(=O)c2c(C)noc2C)cc1 +CCOC(=O)CNc1nc(N2CCN(C)CC2)nc2ccc(Cl)cc12 +Nc1ncc(C(F)(F)F)c(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)n1 +Cc1cc(C)n2cc(C=Cc3nc(-c4ccco4)cn3C)nc2n1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCc1nn[nH]n1 +CN1CN(C2CCC(CNCC(F)F)CC2)c2c(cnc3[nH]ccc23)C1=O +O=C1N(c2ccnc(C3CC3)c2)CCN1c1cnccc1C1CC1 +COc1ccc(N2Cc3cc(C)cc(C)c3C2=O)cc1OCCN1CCC(C)CC1 +CC(C)C=C(C#N)C(=O)N1CCCC1Cn1nc(-c2ccc(Oc3cccc(F)c3F)cc2)c2c(N)ncnc21 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCC(n5cccn5)CC4)ncn3)c2c1 +Clc1ccc(Cl)c(Oc2ccccc2NC(=Nc2ccccc2)NCCCNc2ccnc3cc(Cl)ccc23)c1 +c1ccc2c(c1)c1cnc(Nc3ccc(N4CCNCC4)cn3)nc1n2C1CCCC1 +O=C1CN=C(n2cnc(C3CC3)c2)C=C2c3cccc(-c4cnccc4F)c3CCN12 +Cc1cccnc1-c1cc(N2CCN(C(=O)C(C)(C)C)CC2)ncc1Cl +NCc1cccc(C=Cc2nc3ccc(F)cc3c(=O)n2-c2ccccc2Cl)n1 +Cc1c(CC(=O)O)ccc(NCc2cccc(-c3c(Cc4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)c1C +COc1cc(N2CCC(N3CCN(C)CC3)CC2)ccc1Nc1ncc(F)c(Nc2ccccc2P(C)(C)=O)n1 +Cc1noc(C)c1Cn1cc(N2C(=O)N(Cc3ccc(F)c(O)c3)C(C)(C)C2=O)cn1 +Cc1cccc(Nc2nccc(Nc3c(NC(C)C(C)(C)C)c(=O)c3=O)n2)c1 +Cc1ncccc1Oc1ccc(-c2ccn(CC3CC3)c(=O)c2C#N)cc1Cl +CC1CC(C(=O)NCc2cccc(Cl)c2F)N(C(=O)Nc2cn(C(N)=O)c3ccccc23)C1 +CSC(=O)Nc1cnc(-c2ccc(F)cc2)n(CC(=O)NC(C(=O)C(F)(F)F)C(C)C)c1=O +CNC(=O)c1cccc(C2CN(C)C(=O)c3c(O)c(C(=O)NCc4ccc(F)cc4)nn32)c1 +COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccc(C)o2)cc1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(N3CCC4(CCC4)C3)c2n1 +Cc1cc(Cl)cnc1C(=O)Nc1ccc(F)c(C2(CF)COCC(N)=N2)c1 +O=C(O)CCCC=CCC1C2CCC(C2)C1CNS(=O)(=O)c1ccccc1 +O=C(c1ccc(O)cc1)N1CCc2c(n(Cc3ccc(O)cc3)c3ccccc23)C1 +Cc1cc(C=C2C(=O)Nc3ccc(F)c(F)c32)c2ccccc(OCCCN3CCCCC3)c1-2 +O=C(CCN1CCCC1Cc1ccccc1)c1ccc2c(c1)OCCO2 +CCCCc1nc2ccc(NC(=O)NC(C)C)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(Cc1cccc2ccccc12)NCC(O)c1cc(O)cc(O)c1 +NS(=O)(=O)OCC1OC(n2cnc3c(C#Cc4ccccc4)ncnc32)CC1O +CC1CCC(Oc2cc(C#N)ccn2)CN1C(=O)c1ccccc1CC(F)(F)F +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)s2)cn1C(C)C +OCCC1CN(Cc2ccc3nonc3c2)CCN1Cc1ccsc1 +CCS(=O)(=O)c1ccc(-c2cc(-c3cnnc4c3ncn4C(C)C)ccc2F)c(F)c1 +CCn1cc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)s2)cn1 +COc1cc(C(=O)c2sc(-c3ccccc3)nc2N)cc(OC)c1OC +COc1ccc(CC2CCCN2C(=O)c2nc(C)sc2-c2ccc3c(c2)CCO3)cc1OC +CCN1C(=O)C2(CCCN(C3CCN(C(=O)c4c(NC(N)=O)sc5ccccc45)CC3)C2)N=C1C +Cc1ccc(C)c(S(=O)(=O)NC2CCC(C(=O)N3CCC4(C)c5cccc(O)c5CC3C4(C)C)C2)c1 +COC(=O)C1(C)CCCC2(C)C(CCc3ccc4c(OC(C)=O)ccc(OC(C)=O)c4c3)C3(CCC12)CO3 +CCCN(CCCCNC(=O)c1ccc(-c2ccccc2)cc1)C1CCn2nccc2C1 +CC1c2cc(-c3c[nH]c4cc(F)ccc34)ccc2S(=O)(=O)N1CCS(N)(=O)=O +O=c1[nH]nc(CCc2ccc(C#CC(F)F)cc2)cc1O +CP(=O)(O)CCCC=CCC1C(O)CC(O)C1C=CC(O)COc1ccccc1 +COCCN1CCN(c2ccc(Nc3ncc4ccn(C5CCCCC5)c4n3)cc2)CC1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(Nc3ccc(C(=O)OC(C)C)cc3)n2)n[nH]1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(-c3ccccn3)n2)cc1OC(F)F +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1NC1CCOCC1 +O=C(NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1)C1CCOC1 +Cc1cc2nc3ccc(N(C)C)cc3[n+](-c3ccccc3)c2cc1N +CC1(c2cccc(NC(=O)c3ccc(C(F)(F)F)cn3)c2)COCC(N)=N1 +N=C(N)c1ccc(C(=O)Nc2ccc3c(c2)CC(CC(=O)O)CC3)cc1 +O=C(NCC1CN(c2ccc(N3CCOCC3=O)cc2)C(=O)O1)c1ccc(Cl)nc1 +COc1ccc(CCNC(C)C(O)COc2ccccc2)cc1OC +O=C1CSC(=S)N1CCCCNc1ccnc2cc(Cl)ccc12 +CN(C)C1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +CC1CN(c2cc(-c3n[nH]c4ccc(-c5ccc6ncnn6c5)cc34)ncn2)CC(C)O1 +COc1ccc(-n2nc(C(=O)N3CCOCC3)cc2-c2ccc(Cl)cc2)nn1 +NS(=O)(=O)c1ccc(CCNc2n[n+]([O-])c3cc4c(cc3[n+]2[O-])CCC4)cc1 +N#Cc1c(-c2ccc(OC(F)(F)F)cc2)[n+]([O-])c2ccc(C(F)(F)F)cc2[n+]1[O-] +O=S(=O)(Nc1cc(Sc2ncn[nH]2)c(O)c2ccccc12)c1ccc(C(F)(F)F)cc1 +NC(CCCCB(O)O)(C(=O)O)C1CCN(Cc2ccc(Cl)cc2)CC1 +Cc1cc(C)n(CC2OC(n3cnc4c(NC5CC6CCC5C6)ncnc43)C(O)C2O)n1 +O=C(NCCCOc1cccc(CN2CCCCC2)c1)NC1CCCCC1 +Cc1c(OCC(C)O)cn2ncnc(Oc3ccc4[nH]c(CO)cc4c3F)c12 +CCCCCCCCCCCCCCCCOP(=O)([O-])OCC[N+]12CCC(CC1)CC2 +Oc1ccc(-c2ccnc3cc(Cl)ccc23)cc1CNC1CN2CCC1CC2 +CC(=O)C1=NN2c3cc(F)ccc3OCC2C1(CCCN1CCOCC1)c1ccccc1 +COc1cccc(NC(=O)NC2CCCCC2CN2CCCC(Cc3ccc(F)cc3)C2)c1 +CCNC(=O)Nc1cn2c(-c3ncc(CC)cn3)cc(-c3cccnc3)cc2n1 +COc1ccc(OC)c(-c2cccc3c(N)c4c(nc23)CN(C2CCC2)C4=O)c1 +CCC(C(O)c1ccc(O)cc1)N1CCC(O)(Cc2ccccc2)CC1 +CC[S+]([O-])c1nc(-c2ccccc2)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +COc1ccc2c(c1)CCC1(CCCCN1CCc1ccccc1)C2=O +COc1cccc2c1ncc1c(=O)n(-c3cccs3)c(=O)n(C3CCCC3)c12 +CC(Nc1nc(N)nc(N)c1Cl)c1nc2c(Cl)cc(F)cc2c(=O)n1-c1ccc(N)nc1 +Cc1c2c(cc3c(C(F)(F)F)ccnc13)C(C)CC(C)(C)N2 +O=C(CCCCCCc1ccccc1)c1noc(-c2ccccn2)n1 +COCCC(C)(F)c1nc(COc2cc(OC)cc3oc(-c4cn5nc(OC)sc5n4)cc23)cs1 +CC(C)CN(CC(C)(C)NCC(=O)N1CC(F)CC1C#N)C(=O)c1ccccc1 +O=c1nc(-c2ccc3[nH]ncc3c2)cc(-c2cccc(F)c2)[nH]1 +CCc1c(C)[nH]c2cc(OCCN(C)C)c(Cl)cc2c1=O +O=C(O)CNC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +CC1(c2cc(NC(=O)c3ncc(C(F)(F)F)cc3Cl)cc(F)c2F)CC(C(F)(F)F)OC(N)=N1 +CCNC1CCC(c2c[nH]c3ccc(N=C(N)c4cccs4)cc23)CC1 +COC1CCN(c2nc(-c3c(C)cc(C)cc3C)nc3c2CN(c2cc(C(C)C)ccc2C)CC3)CC1(C)C +O=C(NO)C1COC(c2ccc(COc3cccc([N+](=O)[O-])c3)cc2)=N1 +CCC(CC)Nc1cc(C)nc(Nc2c(C)cc(C)cc2C)c1C +Cn1ccc(Nc2nccc(-c3ccc(N4CCCC4)c(C#N)c3)n2)n1 +CCCC1CC2(CCC1O)CCN(c1ccc(OC(F)(F)F)cc1)C2=O +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2ccn(CC(C)(C)C)n2)CC1 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc31)CC2 +COc1ccc2c(c1)CC1CCC(C2)C1NS(=O)(=O)c1ccc(Cl)s1 +COC(=O)c1scc(-c2ccc(NC(=O)c3cccc(OC(F)(F)F)c3)cc2)c1OC +CC1(C)Oc2cc(C(=O)c3cc4ccccc4s3)cc(O)c2C2CC(O)CCC21 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+O=c1cc(-c2ccccc2F)oc2ccc3ccccc3c12 +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4ccc(Cl)cc4)cc3Cl)nc2c1 +O=C(Nc1cccc(O)c1)C(=O)c1c[nH]c2ccccc12 +Cc1c(C)c2ccc(OCC(=O)NN3C(=O)CSC3=Nc3ccc(Cl)cc3)cc2oc1=O +c1ccc(-c2cc(C3CCN(Cc4ccc(-c5nc6ncccc6cc5-c5ccccc5)cc4)CC3)n[nH]2)cc1 +CCCCc1nc2ccc(N(C)S(=O)(=O)CCC)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C(C=Cc1ccc(O)c(O)c1)OCCOc1no[n+]([O-])c1S(=O)(=O)c1ccccc1 +O=C(Nc1ccccc1)c1nc[nH]c1C(=O)NCCNC(=O)c1[nH]cnc1C(=O)Nc1ccccc1 +C[S+]([O-])c1cccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)c1 +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2cccc(Cl)c2)C(C(=O)NCCCN(CC)CC)C1 +CN(Cc1cccc(-c2cnc(N3CCN(c4ncccc4Cl)CC3)nc2)c1)C(=O)CN +CCN(C(=O)c1cc(C)ccc1F)c1ccnc(NC(C)c2ccccc2)n1 +O=C(O)C1CCC(CN(Cc2ccc(OCCN3C(=O)CCC3=O)c(Cl)c2)C2CCc3cc(Cl)ccc32)CC1 +Cc1ccnc(C)c1C(=O)NCCN1CCCC(CC(c2ccccc2)c2ccccc2)C1 +Cc1ccc2nc(-c3ccc(NC(=O)C4CCN(S(=O)(=O)N(C)C)CC4)cc3)sc2c1 +COc1ccc2sc(C(=O)c3cc(OC)c(OC)c(OC)c3)c(C)c2c1 +CC(C)CC(NC(=O)C(C)NC(=O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(O)CSC1CCCCC1 +CN(C)CCN1C(=O)c2c(O)ccc3cc4ccccc4c(c23)C1=O +C=C(CN1CCC(Cc2ccccc2)CC1)C(=O)c1ccc(OC)cc1 +CN(C(=O)c1ccc(F)cc1)c1nc(-c2ccncc2)cs1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OC3CCCCC3)c(C(=O)O)c2)c1 +O=C(NCc1cc(Cl)ccc1-n1cnnn1)C1CC2CC2N1C(=O)C(O)Cn1cccn1 +Cc1ncnc(N2CCC3(CCNC3=O)CC2)c1C#Cc1ccc(N)nc1 +CC(C)NC(=O)c1ccc(F)c(-c2nc(C(=O)Nc3cnccc3N3CCCC(N)C3)cs2)c1 +Cc1cc(=O)c(Oc2ccc(Br)cc2F)c(-c2ccc([S+](C)[O-])cc2)o1 +Clc1cc(NCCCN2CCCCC2)c2cc3c(nc2c1)c1cc(Cl)ccc1n3CCN1CCCC1 +CC(C)NC(=O)c1ccc(CC2CCN(C3CCN(C(=O)c4ccc(F)c5ccccc45)CC3)CC2)cc1 +O=C(Nc1ccccc1F)c1ccc(-c2cc3scnc3cc2Cl)s1 +Cc1ccc(CN2CCN(C3CCc4cccc5c4N(C3=O)C(C)(C)C5)CC2)cc1 +Cc1c(CCO)sc[n+]1CCCCc1ccc(CCCC[n+]2csc(CCO)c2C)c2ccccc12 +CS(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CN(C(=O)OC4CCOC4)C3)cc2C(N)=O)cc1 +CC(C)NC(=O)Cn1c(-c2cccc(Cl)c2)cn2cc(N3CCC4(CC3)CN(C)C4)cc2c1=O +CCCCCC(C)N(Cc1ccc(CC(C)(C)C)cc1)C(Nc1ccc(OC)cc1OC)C1C(=O)OC(C)(C)OC1=O +COC1CC(C(=O)Nc2ccc(F)nc2)N(c2nc(Nc3cc(C4CC4)n[nH]3)c3cccn3n2)C1 +CC(C)NC(=O)NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 +CCOP(=O)(CC)Cc1ccc(Nc2cc(-c3ccccc3OC)ncn2)cc1 +N#CC1CCCN1C(=O)C1CCC(COc2ccc(Cl)cc2C(=O)O)N1 +O=C1NCc2nc(Sc3ccc(F)cc3)ccc2N1c1c(Cl)cc(C(F)(F)F)cc1Cl +O=C(CCCN1CCN(CCC2Cc3ccccc3C2=O)CC1)c1ccc(F)cc1 +CCCC(O)C#Cc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +COc1cc2c(cc1OC)-c1n[nH]c(-c3ccc(Br)cc3)c1C2 +CC1(C)CC(=O)c2ccc(OCc3ccccc3F)cc2O1 +Cc1cccc(C(=O)Nc2cccc(C#Cc3cncc(C(=O)N=S(=O)(CCCO)CCCO)c3)c2)c1 +COc1ccc2cnc3c(C(=O)OCc4ccco4)cnn3c2c1 +C#Cc1ccc(NCc2nc(-c3ccc4c(c3)OCO4)c(-c3cccc(C)n3)[nH]2)cc1 +Nc1ccc2c(c1)C(C#CC1CC1)(C(F)(F)F)OC(=O)N2 +O=C(O)c1cccc(Oc2ccc(Nc3ncc(NC(=O)C4CCOCC4)c(=O)n3Cc3ccc(Cl)cc3)cc2)c1 +CCCCc1ncc(C=C(Cc2cccs2)C(N)=O)n1Cc1ccc(C(=O)O)cc1 +O=C(NCc1cccnc1)Nc1ccc(S(=O)(=O)N2CCC3(CCNC3)CC2)cc1 +COC(=O)C1CCCN1CCOc1ccc(Cc2ccccc2)cc1 +O=c1c(-c2ccccc2)c[nH]cc1-c1cccc(C(F)(F)F)c1 +N#CCC1(n2ccc(-c3ncnc4[nH]ccc34)c2)CN(C2CCN(C(=O)Nc3ccc(F)cc3Cl)CC2)C1 +COc1cc2c(N3CCN(C(=O)Nc4ccc(OC(C)C)cc4)CC3)ncnc2cc1OCCn1cnnn1 +O=C(NC1CCCC2SCCC(C(=O)O)N2C1=O)C(S)Cc1ccccc1 +O=C(O)c1cc(-c2cccc(COc3ccc4c(c3)CN(C3CCCC3)C4=O)c2)ccc1Cl +CS(=O)(=O)CC(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1c(F)cccc1F +Clc1ccc(-c2nn3ncccc3c2-c2ccnc(Nc3ccc4c(c3)OCCO4)n2)cc1 +CCCCN(CCCC)CCCOc1ccc(-c2csc(-c3cccnc3)n2)cc1 +O=C(Nc1ccc(C2=CCN(C(=O)c3ccc(Cl)cc3)CC2)cc1)N1Cc2ccccc2C1 +CNC(=O)C1OC(n2cnc3c(NCc4cccc(NC(C)=O)c4)ncnc32)C(O)C1O +CC(C)c1nc(C2CC2)cc(-c2ccc(F)cc2)c1C#CP(=O)(O)CC(O)CC(=O)O +CCNC(=O)Nc1cn(-c2ncc(C)c(CCCC(=O)O)n2)c2cc(-c3cccnc3)cnc12 +Cc1noc(C)c1-c1ccccc1CN(C(=O)c1ccc(-c2ccc(C#N)cc2)o1)c1ccc(N2CCNCC2)cc1 +CC(=O)Nc1ccc(COc2ccc(-c3ccc(-c4nc5c(C(=O)O)cc(C)cc5[nH]4)cc3)cc2)cc1 +N=C(N)c1ccc(Oc2cc(Oc3ccc(C(=N)N)cc3)cc(C(=O)NC3CCC(O)CC3)c2)cc1 +COc1ccccc1N1CCN(CCCN2C(=O)C3Nc4ccccc4C3N(C)C2=O)CC1 +COC(=O)c1c(-c2ccc(F)cc2)c(-c2ccncc2)c(N2CCCC2)n1C +CCN(Cc1cccs1)c1ncnc2ccc(-c3ccc4c(c3)OCO4)cc12 +CCOc1cccc(C(=O)NCCCCCC(=O)Nc2ccccc2N)c1 +NC1CCCN(c2nc3c4ccccc4[nH]c(=O)c3n2Cc2ccccc2Cl)C1 +CC(O)(COc1ccc(F)cc1)C(=O)Nc1ccc(C#N)c(I)c1 +NCC1CCC(C(=O)NC(Cc2ccccc2)c2nc(-c3ccc(CC(N)=O)cc3)c[nH]2)CC1 +CCc1cccc(CC)c1-c1cc(C)c2c(n1)CC(C)N(c1c(Cl)c(C3CC3)nn1C)C2 +CNC1CCc2ccc(OCCNS(=O)(=O)CC3CC3)cc2C1Cc1ccc(F)cc1 +CN(C(=O)c1ccc(-c2ccc(C(F)(F)F)cc2)cc1)C1CCN(C(=O)N(C)C2CCN(C3CCOCC3)C2)C1 +Cc1cc(CNC(C)(C)C)ccc1C(C)Oc1cc(-c2cnc3ccccn23)sc1C(N)=O +Nc1c(S(=O)(=O)O)cc(Nc2cccc(Oc3ccccc3)c2)c2c1C(=O)c1ccccc1C2=O +Cc1cc(F)c(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC2CC2)cc1 +Cc1nc(Nc2cc(-c3cccc(NS(=O)(=O)c4ccccc4)c3)n[nH]2)cc(N2CCC(O)CC2)n1 +Nc1ncnc2c1ncn2Cc1ccc(-c2ccc(C[n+]3ccc(N4CCCC4)cc3)cc2)cc1 +Cc1cc(-c2cnn(C(C)(C)C(=O)O)c2)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)N1CCN(c2ccccc2)CC1 +COP(=O)(OC)C(OC(=O)COc1ccc(Cl)cc1)c1ccccc1 +Oc1cc(Cl)ccc1Oc1ccc(Cl)cc1CNCc1ccc2c(c1)CCO2 +Cn1c(=O)c2[nH]c(-c3ccc(COC(=O)Nc4ccsc4)cc3)cc2n(C)c1=O +Cc1nccn1-c1ccc(-c2ccc3c(c2)CCC(C)N3C(=O)c2ccc(O)cc2O)nn1 +CC(O)c1nc2cc(NC(=O)c3ccc(C(C)(C)C)cc3)ccc2s1 +Cc1cc(Br)cc2[nH]c(-c3c(NC(CO)Cc4ccccc4)cc[nH]c3=O)nc12 +O=C(NC(CCN1CC2CN(C(=O)c3ccccn3)CC2C1)c1cccc(F)c1)C1CCOC1 +CC[n+]1c(C=C2Sc3ccccc3N2CCO)sc2ccccc21 +O=C(NCOCCN1CCOCC1)C1(c2ccc(Cl)c(Cl)c2)CCCCC1 +O=C(C[n+]1cc(-c2ccc(Cl)c(Cl)c2)n2c1CCC2)N1c2ccccc2Sc2ccccc21 +CC1CCCN1CCCOc1ccc(N2CCN(C(=O)c3ccc(F)cc3)CC2=O)cc1 +CCCCN1CCC(C(=O)NO)C(CS(=O)(=O)c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1 +CC(=NOCCOc1ccc(CC2SC(=O)NC2=O)cc1)c1cccc(-c2ccccc2)c1 +NC1CN(c2ccncc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)CC(N)C1O +CC(C(=O)O)N1CCCCC(NC(=O)C(S)Cc2ccccc2)C1=O +CCCCC(S)C(=O)NC1(C(=O)NC(Cc2ccc(-c3ccsc3)nc2)C(=O)O)CCCC1 +CC1CN(C(C)CO)C(=O)c2cc(NC(=O)Nc3ccc(F)cc3)ccc2OC1CN(C)S(=O)(=O)c1ccc(Cl)cc1 +Nc1nc(N)c2c(n1)CCC(CNc1ccc(Cl)c(Cl)c1)C2 +OCCCCCNc1nc(Nc2ccccc2)nc(Nc2ccccc2)n1 +CC(=O)c1ccc(NCc2cncn2Cc2ccc(-c3ccccc3)cc2)cc1-c1ccccc1 +O=S(=O)(c1ccc(-c2ccccc2)cc1)N1CCN(c2nc(Cl)ncc2Br)CC1 +O=C(NO)c1cccc(-c2csc(CSc3ccccc3)n2)c1 +Cc1ccc(CN2CCOCC2)cc1NC(=O)c1ccc(Nc2ncc(F)c(-c3ccc(OC(F)(F)F)cc3)n2)nc1 +Fc1ccccc1-c1c[nH]c2ccc(-c3nnc(NCc4ccc5[nH]ccc5c4)s3)cc12 +O=C(CCCOc1ccc(OCc2ccc3ccccc3n2)cc1)NS(=O)(=O)c1ccccc1 +Cc1ccc(-c2ncn(-c3ccc(Nc4nccc(-c5cccc(N6CCOCC6)c5)n4)cc3)n2)cn1 +COc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)CC5)ccn34)c12 +NC(N)=NCCCC(NC(=O)C(c1ccccc1)c1ccccc1)C(=O)NCc1ccc(O)cc1 +COc1cc2ncnc(Nc3cc(NC(=O)c4ccnc(N5CCOCC5)c4)ccc3C)c2cc1OCCN1CCCC1 +Cn1c(=O)c2c(nc(OCc3ccc(Cl)cc3)n2C)n(C)c1=O +CON(C)C(=O)C(c1ccc(-c2ccc(F)cc2)cc1)C(N)C(=O)N1CCC(F)C1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)C1CCC(CNC)CC1 +O=C(Cc1ccccc1)Nc1nnc(CCCCc2ccc(NC(=O)C(O)c3cccc(Cl)c3)nn2)s1 +COc1cccc(CNc2nc(N)c3nc(-c4ccco4)sc3n2)c1 +COc1cccnc1Cn1ccc2nc(N)nc(OCc3ncc(C)o3)c21 +CN(C(=O)CCN1CCN(c2ccccc2)CC1)C1c2ccccc2SCC2CCCCC21 +CCCCCCCN(C(=O)Nc1ccc(C(C)C)cc1)C1Cc2ccc(SC(C)(C)C(=O)O)cc2C1 +CC(C)N1CCC(C(CN2CCN(CCCc3ccccc3-c3ccccc3)CC2)c2ccc(F)cc2)CC1 +Clc1csc2cc(Nc3nccc(-c4ccccn4)n3)ccc12 +Cn1cc(-c2ccc(-c3cncc4ccc(N5CCCC5=O)nc34)cc2)cn1 +CCCC(Oc1ccc(-n2cc(Cl)c(C)n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 +CCc1nc(C(Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)C(Cc2ccccc2)NC(=O)OC)sc1-c1ccccc1 +COc1cc(Br)ccc1NC(=O)C1CCC(N2C(=O)C3C4CCC(C4)C3C2=O)CC1 +CCCN(CCC)c1ccc2cc(C#N)c3nc4ccccc4n3c2c1 +CCCN1CCc2cc(OC)cc3c2C1Cc1ccc(O)c(O)c1-3 +Nc1cc(C(=O)NC(=O)NCCCCCC(=O)NO)ccc1Cl +COc1ccc(-c2ccc3ncc(-c4ccncc4)n3n2)cc1OC +Cc1csc2ccc(N3CCN(c4cnccc4C4CC4)C3=O)cc12 +Cc1cccc(C(=O)N2CCOCC2Cc2cc(-c3ncccn3)ccc2F)c1-n1nccn1 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(CCC(F)(F)F)C1 +CN1C2CC(S(=O)(=O)c3ccccc3)C1Cc1cnc3c(-c4ccc(Cl)c(O)c4)c(-c4ccncc4)nn3c12 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cccc3cc[nH]c23)cc1 +COc1csc(-c2ccc(OCCCOc3ccc4c(c3)CCC4CC(=O)O)c(OC)c2)n1 +CNC(=O)n1ccc2cc(Oc3ccnc(NC(=O)c4ccc(CN5CCC(O)CC5)cc4)c3)c(OC)cc21 +Cn1nnnc1-c1cccc(CC2(C(=O)NC(Cc3ccc(NC(=O)c4c(Cl)cccc4Cl)cc3)C(=O)O)CCCC2)c1 +CCCCN1CCCC(c2ccc(C(=O)N(CC)CC)cc2)(c2cccc(O)c2)C1 +C#CCN1CCN(C(=O)c2c(F)cc(-c3ncnc(CC)c3C#Cc3ccc(N)nc3)cc2F)CC1 +COC(=O)c1ccc2c(Nc3ccc(Cl)cc3)nc(N3CCOCC3)nc2c1 +Cc1cc(-c2nnc(N)nc2-c2cccc(F)c2)cc(C)n1 +COC(=O)C1C2CCC(CC1c1ccc(-c3nccs3)cc1)N2 +O=C(Cn1cc(Nc2nncc3cc(OCCCN4CCCC4CO)ccc23)cn1)Nc1cccc(F)c1 +O=C(NCc1ccc(Oc2ccccc2)cc1)C(CSCC1CCCCC1)NC(=O)C1CSCN1CCO +N#Cc1cc(-c2ccc(F)cc2)ccc1N1CCOc2cc(S(=O)(=O)Nc3nccs3)ccc21 +O=C(O)CC1CC2(CCN(C(=O)NC3C4CC5CC(C4)CC3C5)CC2)c2cc(Cl)ccc21 +CCCN(CCOc1cccc(CN(CC)CC=CC#CC(C)(C)C)c1)S(=O)(=O)c1cccs1 +Nc1nc(-c2cccc(C(=O)N3CCOCC3)c2)cn2nc(-c3ccco3)nc12 +O=C1Nc2c(ccc(F)c2F)C1(CC1CCCCC1)c1ccc(O)cc1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2c(c1)OCO2 +Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2ccc(C(N)=O)cn12 +CN(C)c1cccc2c(S(=O)(=O)NCCNC(=O)NC34CC5CC(CC(C5)C3)C4)cccc12 +O=c1[nH]ccc2cc(OCCCN3CCN(c4cccc5sccc45)CC3)ccc12 +CC(Oc1cc2onc(CCC(=O)O)c2cc1Cl)c1ccc(Cl)cn1 +Cc1c(Cl)cccc1C(=O)N1CCCC(c2nc(-c3ccccc3Br)no2)C1 +Cc1ccccc1C(C(=O)NC1CCOCC1)N(C(=O)Cc1cccs1)c1cccc(F)c1 +CN1CCC(c2ccc(Cl)cc2)C(C(=O)NCc2ccc(CNC(=O)c3ccc(C(F)(F)F)cc3)cc2)C1 +COc1cc(C=C2CC(C(C)C)CC(=Cc3cc(OC)c(OC)c(OC)c3Br)C2=O)c(Br)c(OC)c1OC +Cc1cc(-c2cc(C(=O)c3cccc(O)c3)cs2)ccc1O +Cc1c[nH]c2ncnc(N3CC(C)N(C(=O)Nc4cccc(Br)c4)C(C)C3)c12 +O=C(CCCCNC1=NCCCN1)Nc1ccc(CC(NC(=O)C2CCCN2S(=O)(=O)c2ccccc2)C(=O)O)cc1 +COc1cc(C=C2CCCN3C2=NOCC3C(C)(C)C)ccc1-n1cnc(C)c1 +Cn1ncc(C(=O)N2CCC(Nc3cc(=O)n(C)c4cc(F)c(F)cc34)CC2)c1Cl +COc1cc2c(cc1N1CC(C)N(C)C(C)C1)N(C(=O)Oc1cccc(C(F)(F)F)c1Cl)CC2 +COc1ccc([N+](=O)[O-])cc1Nc1nc2c(s1)CCCCc1nc(NC(=O)C(C)(C)C)sc1-2 +CC(=O)Nc1nc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(C#N)cc2)n1 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCN(C)C +CCCC1SC(=Cc2nc3cccc(C)c3[nH]2)NC1=O +Cc1[nH]c2ccccc2c1CN1CCCC2(CCN(c3cnc4ccccc4n3)CC2)C1=O +O=C(O)COc1ccc(SCc2ccc(OCc3ccc(F)cc3)cc2)c2c1CCC2 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3ccccc3C(F)(F)F)cc2)C1CO +Cn1cc(-c2cccc(F)c2F)cc(NC(=O)N2CCC(n3c(=O)[nH]c4ncccc43)CC2)c1=O +COc1ccc2cnn(-c3cnc4[nH]cc(C(=O)NC(C)(C)C)c4n3)c2c1 +O=C(CCCCCCNC(=O)c1nc(-c2nccs2)sc1C1CC1)NO +COc1ccc(-c2cc(=O)[nH]c(=S)n2CCO)c(OC)c1 +CCc1n[n+]([O-])c2cc(OCCN(C)C)ccc2[n+]1[O-] +Cn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)NC3 +O=S(=O)(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccc(-c2cnc(CC3CCCC3)o2)cc1 +COc1cc(C(=O)c2ccn(-c3cccc(O)c3)c2)cc(OC)c1OC +CCCN(CC1CC1)C1CCc2ccc3[nH]cc(C=O)c3c2C1 +Cc1cc(C#N)cc(C)c1Oc1ccc([N+](=O)[O-])c(NC2CCN(Cc3ccccc3)CC2)c1 +O=C(NCCc1nc(-c2ccc(F)cc2)cs1)c1cccs1 +Cn1cc(-c2cnn3c(Nc4ccccc4)cc(C4CCCNC4)nc23)cn1 +O=C(O)CC(=O)Nc1cccnc1C(=O)Nc1nccs1 +CC(C)(C)c1nc2nc(-c3ccccc3Cl)c(-c3ccc(Cl)cc3)cc2c2nncn12 +CCCCn1nc(-c2nc3ccccc3s2)nc2c(=O)n(CC)c(=O)nc1-2 +O=C(CCCCCn1cc(-c2ccc3cccnc3c2)nn1)NO +O=C(Nc1ccc(N2CCOCC2)cc1)c1cn(Cc2c(F)cccc2Cl)c2ccc(=O)[nH]c2c1=O +CCOCCOc1cc2c(ccn2C(=O)NC)cc1Oc1ccnc(NC(=O)c2ccc(C3CCN(CCO)CC3)cc2)c1 +COC(=O)Cc1sc2nc(-c3cccs3)nc(NN3C(=O)C=C(C)C3=O)c2c1C +NC(=O)c1cccc2c(NCc3cccc(NC(=O)c4cccc(OCCCO)c4)c3)ncnc12 +Oc1nc(-c2cc(-c3ccon3)n(Cc3ccc(F)cc3F)n2)ncc1F +COCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3cc(Cl)ccc3Br)cc2[nH]1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccc(O)cc1Cl +Cc1c(C(=O)NCCCN2CCN(c3cccc(Cl)c3)CC2)cc(-c2ccccc2)n1C +OCc1ccc(-c2cn3c(-c4cn[nH]c4)cnc3cn2)cc1 +COc1cccc(CCNc2nc(N)c(C(=O)N=C(N)N)nc2Cl)c1 +Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)NCc1ccccc1CCN +Nc1ccccc1NC(=O)C=Cc1cccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)c1 +CC(C)N(C(=O)C1CCC2C3CCc4cc(CP(=O)(O)O)ccc4C3CCC12C)C(C)C +COc1cccc(OC)c1-c1cc(C(=O)NC2(C(=O)O)CCCCC2)nn1-c1ccnc2cc(Cl)ccc12 +O=C(c1cn(C(=O)OCc2ccccc2)c2ccccc12)C1CSC(c2cccnc2)N1 +CC(C)CN(c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1)S(=O)(=O)N(C)Cc1ccc(F)cc1 +CC1COCCN1c1ccnc(-c2c[nH]c3ccc(-c4nnc(N)o4)cc23)n1 +COC=CC12CCC(O)CC1=CCC1C2CCC2(C)C(O)CCC12 +COc1ccc(Nc2ncc(CN3CC4(C3)NC(=O)NC4=O)cc2-c2nc(C)nc(N)n2)cn1 +Cc1nc(O)c2cc(NCc3ccc(C(=O)NC(CCC(=O)O)C(=O)O)s3)ccc2n1 +COC(=O)C(Cc1cccs1)NC(=O)c1c(C)n(CCN2CCOCC2)c2c(OC)cccc12 +CC(C(O)c1ccc2c(c1)CN(C)C(=O)N2)N1CCC(O)(c2ccc(F)cc2)CC1 +CN(C)CCNc1cc(-c2ccc(N3CCN(C)CC3)cc2)nc2ccccc12 +Cc1ccc(C(=O)N2CCC3(CC2)OCc2cc(C#N)ccc23)cc1NC(=O)c1ccc(N(C)CCO)nc1 +CSCCC(NC(=O)c1ccc(CSc2cccnc2)cc1-c1ccccc1)C(=O)O +O=C(Cn1c(-c2ccc(F)cc2)nc2ccccc21)Nc1ccc(Cl)cc1 +CCn1cnc2c(Nc3cccc(OC)c3)nc(NCCN)nc21 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+CC(C)(O)C1CC(Nc2nc(-c3cc(F)ccc3O)nc3ccccc23)CN1 +COc1cc(NC(C)CCCN(Cc2ccccc2OC)C(=O)Nc2cccc(F)c2)c2ncccc2c1 +CN(C)C1(c2ccccc2)CCC(c2ccccc2)(N(C)C(=O)NCc2ccccc2)CC1 +COc1ccc2c(c1)C(CCNC(=O)C(F)(F)F)=CC2 +N=C(N)NC1CCC(C(=O)Nc2ccc(CC(NC(=O)C3CCCN3S(=O)(=O)c3ccccc3)C(=O)O)cc2)CC1 +O=C1OC(=CCn2c(=O)[nH]c(=O)[nH]c2=O)C(OCc2ccccc2)=C1OCc1ccccc1 +Nc1nnc(-c2ccc3[nH]cc(-c4nccc(Nc5ccccc5)n4)c3c2)o1 +CC1(c2cc(NC(=O)c3cnc(C(F)F)cn3)cc(F)c2F)CC(C(F)(F)F)OC(N)=N1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3ncco3)cc2CN2CCC(C)(C)C2=O)c1C +CN(C)CCOc1ccc(-c2cccc(N)n2)c2ccccc12 +CCSc1ccn(C2OC(COP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)n1 +CCOC(=O)c1nnc(-c2ccccc2)nc1Sc1ccccc1Cl +COP(=O)(O)CNC(Cc1ccc(-c2ccccc2)cc1)C(=O)NCCC(=O)O +CCCCCCCCNC(=O)c1cn2c3c(c(N4CCN(C)CC4)c(F)cc3c1=O)OCC2C +Oc1ccc(-c2ccc(-c3cn(CSc4ccccc4)nn3)cc2)cc1 +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4cc(OC)c(O)cc4[nH]3)CC3CC123 +Cc1cc(OCCCc2c(C(=O)O)sc3ccccc23)cc(C)c1Cl +COc1ccc(S(=O)(=O)N2CCCNCC2C(=O)NO)cc1 +c1ccc(-c2cc(-c3ccncc3)c(-c3cccs3)[nH]2)cc1 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+COc1ccc(C2CC2COc2nc(C)ncc2-c2cc(=O)n(C)cc2C#N)nc1 +O=C(O)CC(NC(=O)CNC(=O)c1cc(O)cc(NC2=NCCCN2)c1)c1cc(Br)cc(Br)c1O +Cc1ccc2nc(C)c3nnc(-c4cc(C(C)O)ccc4Cl)n3c2n1 +COC(=O)c1ccc(Cn2c(=O)n(Cc3nc4ccccc4n3CCN(C)C)c3ccccc32)cc1 +c1cc(-c2ncco2)c2c(c1)C(c1ncc[nH]1)CC2 +O=C(NCc1ccc(OC(F)(F)F)cc1)Nc1cccc2ccc(O)cc12 +CCCCCc1ccc(C(=O)N(CCN2CCC(Cc3ccccc3)CC2)Cc2ccc(-c3ccc4c(c3)OCO4)cc2)cc1 +CCNC(=O)Nc1cn(-c2nccc(C)n2)c2cc(-c3cccnc3)cnc12 +CCOC(=O)C1Oc2ccc(CNC(=O)C3SCCN3C(=O)CC(N)Cc3cc(F)c(F)cc3F)cc2O1 +NC(=O)c1cc(-c2ccccc2)cc2c1[nH]c1ccc(C(=O)N3CCOCC3)cc12 +CCOc1ccc(-n2c(C)c3c(C)nnc(CC(C)C)c3c2C)cc1 +CNc1cccc(F)c1C(=O)OC1C(C)=CC23C(=O)C(C=C(CO)C(O)C12O)C1C(CC3C)C1(C)C +CC1(O)CCC(Nc2ccc3nnc(-c4cccc(C(F)(F)F)c4)n3c2)CC1 +N#Cc1c2c(c(N3CCN(Cc4ccccc4)CC3)n3c1nc1ccccc13)CCC2 +CC(C)C(NS(=O)(=O)c1ccc(-c2cccc(F)c2)cc1)P(=O)(O)O +O=C(Nc1nc2ccccc2n1CCN1CCCC1)c1ccc(Cl)cc1 +COCc1cc(C#N)cnc1C(=O)Nc1ccc(F)c(C2(C(F)F)N=C(N)OC3CC32)c1 +CN1CCN(C)C(C)(c2nc(O)c(O)c(C(=O)NCc3ccc(F)cc3)n2)C1 +C=CCOC(=O)C1=CSC2C(C(C)OC(C)=O)C(=O)N12 +C#CCOc1ccc2c(c1)c(-c1ccc(C(C)C)cc1)nc(=O)n2Cc1cccc(OCC(=O)O)c1 +CC(C)NC(=O)c1ccc2cc(C(O)(c3c[nH]cn3)C(C)C)ccc2c1 +CCON=C(c1ccc(Br)cc1)C1CCN(C2(C)CCN(C(=O)c3c(C)ccnc3C)CC2)CC1 +Cc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +O=C(NO)c1cnc(NC2(c3ccc(F)c(F)c3)CC2)nc1 +CC(NC1CCN(c2ccc(C(=O)NC(CO)(CO)CO)cc2)C1)c1cccc2ccccc12 +Cc1cnc2c(NCCN(C)C)nc3cc(-c4ccccc4)sc3n12 +CC1(C(=O)Nc2nccs2)CC2c3ccccc3C1c1ccccc12 +NC1=NC2(CO1)c1cc(Br)ccc1OC(Cc1ccccc1)C21COC1 +O=C(NCCC1(N2CCOCC2)CCCC1)c1cc2[nH]c(=O)c3ccccc3n2n1 +COC1C(O)C(O)C(Oc2ccc3cc(NC(=O)c4cc5ccccc5[nH]4)c(=O)oc3c2C)OC1(C)C +CCCS(=O)(=O)c1ccc(C)c(C#Cc2cc(C#N)ccc2OCC(=O)O)c1 +C=CCC(C(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)C(C)C)c1cc(Br)ccc1OC +COCCCn1c(NC(=O)c2ccc(Cl)cc2)nc2cc(CN(C)C3CCCCC3)ccc21 +CN(C(=O)Cc1cccc2occc12)C1CCC2(CCCO2)CC1N1CCCC1 +FC(F)(F)c1cccc(Sc2ccc3nnc(-c4ccncc4)n3n2)c1 +CCOc1ccc(F)c(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)c1 +Cc1ccc(Nc2cnc(-c3cccc(OC(C)C)c3)c(C)c2)c(C(=O)O)c1 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+CCC(=O)N1N=C(c2ccccc2)CC1c1ccc(Cl)cc1 +CCOC(=O)Cn1c2ccc(OC)cc2c2nc3ccccc3nc21 +O=C(NC1Cc2ccccc2C1)c1cccc(-c2n[nH]c3ccc(-c4ncn[nH]4)cc23)c1 +CCCOC(=O)Nc1ccc2oc3cc(S(=O)(=O)NC(C(=O)O)C(C)C)ccc3c2c1 +CCc1cccc(OC)c1CCc1ccc(O)c(C(=O)OC)c1 +CCCN(CCC)C(=O)c1cccc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)CNC(C)C(=O)NCC(C)C)c1 +COC(=O)CCC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2CNCCc2cccs2)CC1 +O=C(Cc1cc[n+]([O-])cc1)N1CCN(C2c3ncc(Br)cc3CCc3cc(Cl)cc(F)c32)CC1 +CCC1C(C)C(Nc2ccccc2)c2ccccc2N1C(=O)c1ccc(OC)cc1 +Cc1[nH]c(C)c(-c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)c(=O)c1Br +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC(CNS(=O)(=O)N1CCOCC1)c1ccccc1 +CN1CCC(OCC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)CC1 +COc1ccc(-n2c(=O)[nH]c3cc(C(=O)NCc4ccc5c(c4)OCO5)sc3c2=O)nc1OC +Cc1c2c(n3c1CCCNCC(C)(C)Nc1cc-3ccc1C(N)=O)CC(C)(C)CC2=O +COc1ccc(C(=O)C(Cc2cc(OC)c(OC)c(OC)c2)=C(C(=O)O)c2ccc3nsnc3c2)cc1Cl +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccncc4)nc23)N1 +COCCN(CCOC)CCC(C)(C)Nc1nc2c(-c3cc4c([nH]3)CNC4=O)cccc2c(=O)n1C 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+CN1CCN(c2nc(-c3ccco3)cc(-c3cccs3)n2)CC1 +COC(=O)C(N)CCB1OC2(C)CCC3CC2(O1)C3(C)C +CC(C)S(=O)(=O)N1CC=C(c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)CC1 +CN1C(=N)NC(C)(c2sc(-c3cc(F)cc(-c4cnco4)c3)cc2F)CS1(=O)=O +CC(NC(=O)N1CCC(c2ccc(O)cc2O)CC1)c1ccccc1 +CC(=O)N1CCN(C(=O)c2cccc(Sc3cnc(NC(=O)c4ccc(N(C)C)cc4)s3)c2)CC1 +Cc1c(-c2nnc(C3(c4ccc(Cl)cc4)CC3)o2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +CCNC(=S)Nc1cc(-n2cnc(CN(C)C)c2)ncn1 +CC(C)(C)n1c(=O)[nH]c2cc(Nc3ccccc3)ccc21 +Nc1cccc(N2CCN(CCCN3C(=O)CCc4c(Cl)cccc43)CC2)c1 +Cc1ncoc1-c1nnc(SCCCN2CCC3(CC3c3ccc(F)cc3)C2)n1C +Cc1c(S(=O)(=O)C(F)(F)F)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 +CS(=O)(=O)c1ccc(C(=Cc2ccccc2)c2ccccc2)cc1 +CCCCCCc1csc(-c2ccc(S(=O)(=O)Nc3ccc(CCNCC(O)c4cccnc4)cc3)cc2)n1 +CNC(=O)Nc1ccc(-c2cc(-c3ccnc(Nc4ccc(C)c(S(=O)(=O)N(C)C)c4)n3)ccn2)cc1 +c1ccc(CCn2c(N3CCNCC3)nc3ccccc32)cc1 +CC1CN(c2ncc(C(=O)NCc3ccc(Cl)c(Cl)c3)cc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +CC(Br)C=CC(=O)N(Cc1ccc(Cl)cc1)CC(C)C +COc1cc(C(C)(C)C(=O)NCc2ccc(C(C)(C)C)cc2)ccc1NS(C)(=O)=O +CCS(=O)(=O)Nc1cc(Cl)cc(-c2[nH]c(C3CC3)nc2-c2ccnc(NCC(C)NC(=O)OC)n2)c1F +CCn1ncc2c(F)cc(C(=O)Nc3nnc(C4(C)CN(C(C)=O)C4)s3)cc21 +O=C(CCc1cnnn1-c1ccccc1)c1cccc(F)c1 +O=C1Nc2cccnc2N(C(=O)CN2CCCCC2CN2CCCCC2)c2ccccc21 +O=C(Cc1cccc2ccccc12)N1CCC(CNCCCCNCC2CCCCC2)CC1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1-n1cc(-c2cncc(N(C)C3CCOC3)c2)nn1 +COc1ccc2c3c(c(=O)oc2c1)CN(Cc1ccc(C)cc1)CC3 +Cc1noc(-c2ccc(Nc3nn(C4(CC#N)CCN(C(=O)OC(C)(C)C)CC4)cc3C(N)=O)cc2)n1 +O=C(Nc1ccc2c(c1)OC(F)(F)O2)c1ccccc1NCc1ccnc(NCCCn2ccnc2)c1 +COc1cc(-n2cnc3cc(-c4cccc(I)c4)sc3c2=O)ccc1OCCN1CCCC1 +CS(=O)(=O)NC(CNC(=O)c1cc2sc(CCC3CCNCC3)cc2s1)C(=O)O +CC12CCC(C1)C(C)(C)C2NC(=O)c1cn(CCCCO)c2cc(F)ccc2c1=O +CC=C1C(O)CC2C3CCC4CC(N5CCCCC5)CCC4(C)C3CCC12C +COC1Cc2sccc2C2(CCN(CCc3ccccc3)CC2)O1 +CS(=O)(=O)c1ccc(-c2c(-c3ccc(F)cc3)nc3sccn23)cc1 +CC1(C)C=C(CSc2nc3c(C(N)=O)cccc3[nH]2)CC(C)(C)N1O +CS(=O)(=O)c1ccc(-n2nc(C(F)F)c(C#N)c2-c2cc(F)cc(F)c2)cc1 +COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c(sc4ccc(NC(=O)Cc5ccccc5)cc43)c2=O)CC1 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+O=C1CC(NC(=O)C2COCC3CC=CCC(NC(=O)c4ccc5ccccc5c4)C(=O)N32)C(O)O1 +COc1nc2ccc(C(O)(c3ccccc3)C3CCN(C(C)=O)CC3)cc2c(Cl)c1Cc1ccc(-n2cccn2)cc1 +CC(=O)OC1(C)CCC2CC1OOC2(C)C[S+]([O-])c1ccccc1 +CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(=O)O)c1C +N#Cc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCO)CC1 +Cc1cc(SC2=C(O)OC(CCC3CCCO3)(C(C)C)CC2=O)c(C(C)(C)C)cc1CO +COc1cc(F)cc(C#Cc2c(N)ncnc2NC(C)c2nc3cccc(Cl)c3c(=O)n2-c2ccccc2)c1 +CCCC[N+]12CCC(CC1)C(NC(=O)c1cc(Cl)c(N)c3c1OCC3)C2 +CC#Cc1ccc2nccc(NC(=O)Nc3cccc(C(F)(F)F)n3)c2c1 +CCOc1cc(=O)n(C)cc1-c1cc(N(Cc2cncnc2)S(=O)(=O)CC)ccc1Oc1ccc(F)cc1F +FC(F)Oc1ccc(Cl)cc1CN1CCN(c2nc3cnccc3nc2NC2CC2)CC1 +CC(C)(C)c1ocnc1C=c1[nH]c(=O)c(=Cc2cccc(OC(F)(F)F)c2)[nH]c1=O +CCOC(=O)Cn1c2ccc([N+](=O)[O-])cc2c2ncnc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c21 +C=CCn1c(SCC(=O)Nc2cc3oc4ccccc4c3cc2OC)nnc1-c1cnccn1 +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)N1CCCN(C(=O)c2ccccc2O)CC1 +Nc1ccc2ccc(CCNCCCc3cccc(F)c3)cc2n1 +CCN(CC)CCCCNc1cc2nc(NC(=O)NC(C)(C)C)c(-c3cc(OC)cc(OC)c3)cc2cn1 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+COc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCC1CCN(C(N)=NC#N)CC1 +CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCCCN1CCOCC1 +COc1sc(S(=O)(=O)NC(=O)Nc2ncc(Br)s2)cc1C +CCCCNC(=O)NC1(c2ccccc2)CCN(c2ncnc3c2nc(-c2ccccc2Cl)n3-c2ccc(Cl)cc2)CC1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(-c3cccc(CO)c3)nc21 +CCCCCC=CCC=CCC=CCC=CCCCC1=NC(C)CO1 +CC12C3CCC(C3)C1CN(c1ccc(C#N)c(C(F)(F)F)c1)S2(=O)=O +O=C1Cc2cccc(Oc3ccc(Nc4ncnc5ccn(CCO)c45)cc3Cl)c2N1 +CC(C)(C)C(=O)OCOP(=O)(COC(CO)Cn1cnc(N)nc1=O)OCOC(=O)C(C)(C)C +COc1ccncc1C(=O)Nc1cn2nc(-c3cn(C)nc3-c3ccc(F)cc3)ccc2n1 +CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)N4CCN(Cc5cccc(Cl)c5)CC4)cc3)[nH]c2c1=O +COc1ccccc1C(N)CNc1cc(C)nc2nc(NC(CC#N)c3cccc(Cl)c3)nn12 +CC(=O)c1cnc2cc(F)c(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(CN(C)C)CC1 +COc1ccc(S(=O)(=O)N2CCc3cccc(NC(=O)C(C)(C)C)c32)cc1 +CN(C)C1(CNCCc2ccccc2)COc2ccccc2OC1 +CC(C)S(=O)(=O)CC(N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1)C(C)(C)C +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1N1CC2CC2C1 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+O=C(NCC1CCCN1)C(O)c1ccc(-c2noc(-c3onc(-c4ccccc4)c3C(F)(F)F)n2)cc1 +Nc1nc(N)c(CCCN(C=O)c2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)c(O)n1 +NC(=O)c1ccc2[nH]c(-c3ccc(OC4CCCN(Cc5ccc(Cl)cc5)C4)cc3)nc2c1 +O=C(NCc1ccc(OC(F)(F)F)cc1)c1ncc([N+](=O)[O-])[nH]1 +CCOCCn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 +O=C1c2ccc(Cl)cc2CCC12CCN(CCc1ccccc1)CC2 +O=C(Nc1cccnc1)c1cc(Cl)ccc1OCc1ccccc1 +COc1cccc2c1-c1ccc(NS(C)(=O)=O)cc1C(c1cccc(C)c1)O2 +Cc1ccccc1-c1c2c(nn1C)CCc1cnc(Nc3ccc(OCCCN(C)C)cc3Cl)nc1-2 +CCOc1ccccc1-c1cc(F)c(NC(=O)c2cscc2C(=O)O)c(F)c1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2cccnc2)cc1 +CC(NC(=O)Nc1cc2[nH]nc(Nc3ccccc3)c2cn1)c1ccccc1 +COc1ccc2c(Oc3ccc(NC(=O)c4c(-c5cc(C)on5)n(C)n(-c5ccccc5)c4=O)nc3)ccnc2c1 +CCCS(=O)(=O)Nc1ccc(-c2ccc(C#N)n2C)cc1 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1cccc2nonc12 +Cc1nsc(C2CCN(C(=O)C3CNC(C(=O)N4CCCC4)C3)CC2)n1 +O=C(O)c1ccc2c(c1)nc(-c1ccc(OC(c3ccc(F)cc3)c3ccc(F)cc3)cc1)n2C1CCCCC1 +CCOc1cc(C=C2CN(C)CC(=Cc3ccc(O)c(OCC)c3)C2=O)ccc1O +Cc1ccc(C(=O)OC2(c3ccc(Cl)cc3)CCN(CCCC(=O)c3ccc(F)cc3)CC2)cc1 +O=C(NCCCCN1CCN(c2ccc(F)cc2)CC1)c1cc2ccccc2cn1 +COc1ccc(-c2cccc3cnc(Nc4ccc(-n5cnc(-c6ccccn6)n5)cc4)nc23)cc1F +N=C(N)c1ccc(OCCCCCCOc2ccc(C(=N)N)cc2)cc1 +O=S(=O)(NC1CCC(N2CCC(c3ccccc3OC3CC3)CC2)CC1)c1ccc2c(c1)OCO2 +COc1cc2[nH]c(=O)n(CCc3c[nH]cn3)c(=O)c2cc1-c1cnco1 +CC(C)CN(c1ccc(F)cc1)S(=O)(=O)c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1 +COc1cccc(F)c1CN1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccc5nc(C)sc5c4)c3c2)C1 +Nc1nc(N)c(-c2cccc(Cl)c2)c(CCCc2ccccc2)n1 +OCC1OC(n2cnc3c(CSc4ccc(I)cc4)ncnc32)C(O)C1O +CC(C)COc1cc(-c2ccc(CC(C)NCC(O)c3ccccc3)cc2)ccc1C(=O)O +COC(=O)c1ccccc1S(=O)(=O)CCn1c([N+](=O)[O-])cnc1C +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3ccco3)c3ccccc32)CC1 +O=C(Cc1ccc(Cl)c(Cl)c1)N1CCc2occc2C1CN1CCCC1 +Cc1ccccc1-n1c(Cn2nc(-c3cc(O)cc(F)c3)c3c(N)ncnc32)nc2cccc(C)c2c1=O +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccnc(C)c4)c3c2)CCC1C(=O)NN(C)C +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2ccco2)[nH]c1=O +CCCC(=O)N(Cc1ccc2c(c1)OCCO2)c1cc(-c2nnn[nH]2)ccc1F +O=C1COc2cc(Cl)c(Cl)cc2N1CC(=O)N1CCCC(c2ccccc2)C1CN1CCOCC1 +CCCCN(CC)c1cc(C)nc2c1NC(=O)CN2c1ccc(Cl)cc1Cl +CCN(CC)c1ccc(N=Cc2ccc(Sc3nc4ccccc4s3)o2)cc1 +C=C1CC(COC2CCC3(OC(C)=O)C4Cc5ccc(O)c6c5C3(CCN4CC3CC3)C2O6)OC1=O +CN(CC(=O)O)Cc1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)cc1 +CC(NC(=O)CCc1nc2cccnc2n1Cc1ccccc1)c1ccccc1 +N#Cc1ccc(Cn2cncc2CNC2C(=O)N(c3cc(Cl)cc(Cl)c3)CCc3ccccc32)cc1 +CC(C)Oc1ccc(C(C)Nc2ncc(F)c(N3C(=O)OCC3C(C)C)n2)cc1 +NCCCCCNc1cc(-c2ccc(F)cc2)nc2ccccc12 +Nc1nc(Cl)c(-c2nc3ccccc3s2)c(NC2CC(CO)C(O)C2O)n1 +Cc1cn(CCCCN2CCN(c3cc(C(F)(F)F)nc(C(C)(C)C)n3)CC2)c(=O)[nH]c1=O +OCc1csc(-c2ccnc(Nc3cc(O)cc(C(F)(F)F)c3)n2)n1 +FC(F)(F)c1cccc(-c2nnc3ccc(NC4CCOCC4)nn23)c1 +COc1ccccc1-c1ccc2c(ccc3sc4c(c32)NCC(C)NC4=O)n1 +Cc1ccn2nc(CCc3nc(N4CCCC4)n(C)n3)nc2c1C +O=c1c(Nc2ccccc2)c(Nc2ccc(Cl)c(S(=O)(=O)N3CCC(N4CCCCC4)CC3)c2O)c1=O +CCOC(=O)c1cc(CCn2cnc3c2NC=NCC3O)c2c(c1OCc1ccccc1)CCCC2 +CC(C)C1CCC(N2CCC3(CC2)C(c2ccccc2)CC2CN(C)CC23)CC1 +CCN(Cc1ccncc1)C(=O)Cc1c(-c2ccccc2)[nH]c2ccccc12 +FC(F)(F)c1ccc(C(NC2CN(c3ncccn3)C2)c2cccnc2)cc1 +CCOC1(c2ccccc2)c2cc(Cl)ccc2NC(=O)N1C +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(N(C)CCCO)cc3)CC21C +Cc1cccc(C(=O)N2CCN(CC(N)CS)CC2)c1C +NC1(C(=O)O)C(OCc2ccc(-c3ccccc3)cc2)CC2C1C2(F)C(=O)O +COc1ccc(-c2cn(-c3ccccc3)c3ncnc(N)c23)cc1 +N#CCOc1c(-c2ccccc2)c(O)nc2cc(Cl)ccc12 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1nc(N2CCOCC2)c2sccc2n1 +O=C(NCc1ccc(-c2cc(NC(=O)c3ccc(OCCN4CCCC4)cc3)[nH]n2)cc1)OCc1cccnc1 +CN(C)CC(=O)N1CCC(c2nc(-c3cnc(N)c(-n4nnc5ccccc54)n3)nn2C)CC1 +CC(=O)Nc1cccc(C2CCN(CCCn3nc(-c4ccc(Cl)cc4)c4cc(F)ccc4c3=O)CC2)c1 +Cc1cc(C(=O)NCCc2ccc(-c3ccccc3)cc2)cc(C)c1CC(N)C(=O)N1Cc2ccccc2CC1C(=O)O +CN(C)c1ccc(Oc2ccc3c(Cn4ccnc4)cc(=O)oc3c2)cc1 +O=C(O)COc1ccc(Cl)cc1CN1CCCN(S(=O)(=O)Cc2ccccc2)CC1 +CC(=O)c1nn(CC(=O)N2C(C(=O)NCC3C(C)(C)C3(Cl)Cl)CC3CC32)c2ccc(OCc3ncccn3)cc12 +CC(CO)Nc1nc(SCc2cccc(F)c2F)nc2[nH]c(=O)sc12 +CCCCCN(C)C(=O)C(=O)c1c(-c2ccccc2)[nH]c2ccc(Cl)cc12 +c1ccc2c3c([nH]c2c1)C(Cc1ccc2c(c1)OCO2)NCC3 +O=C(c1cccs1)N(c1ccccc1)C1CCN(Cc2ccccc2)CC1 +COc1c(OCCF)cccc1C(O)C1CCN(CCc2ccccc2)CC1 +CS(=O)(=O)c1ccc2c(c1)CCN2C(=O)COc1ccc(Cl)c(Oc2cc(Cl)cc(C#N)c2)c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1CCc3ccccc31)CC2 +COc1cccc2sc(Nc3nc(-c4ccccn4)cs3)nc12 +Cc1ccc(-n2nc(Nc3cc(C)[nH]n3)c3ccccc3c2=O)cc1 +CC(=O)SCC(=O)c1ccc(NS(=O)(=O)c2ccc(OCCCN(C)C)cc2)nc1 +CS(=O)(=O)NCCc1cn(Cc2ccc(C(=O)NO)cc2)c2ccccc12 +O=C(NCCCCCCNC(=O)N1Cc2ccncc2C1)c1ccccc1 +O=C(NC1CC(C(=O)O)Nc2cc(Cl)cc(Cl)c21)OCc1ccccc1 +O=C(O)c1cc2[nH]c(-c3ccccc3)c(C3CCCCC3)c2s1 +Cn1nc(C(=O)N2CCc3ccccc3C2)c2c1CCC(N1CCN(Cc3cccc(F)c3)CC1)C2 +CN(Cc1nc(CC2(C3CCCC(C4CC4)N3S(=O)(=O)c3ccc(Cl)cc3)CC2)no1)C(C)(C)CO +CC(O)(c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1)C(F)(F)F +COc1cc(C(=O)c2c(N)sc(C#Cc3ccsc3)c2C)cc(OC)c1OC +C[Se]c1ccc(N(C)c2nc(C)nc3ccccc23)cc1C +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1ccc(O)c(C(=O)O)c1 +Cc1cc2ccccc2n1CCNC(=O)c1ccc(C(=O)OC(C)(C)C)cc1 +COCCN1CCN(c2cc(-c3n[nH]c4ccc(OC(C)C)cc34)ncn2)CC1 +O=C(NCc1cn(Cc2ccccc2)nn1)c1cn(Cc2ccccc2)nn1 +O=S(=O)(Nc1ccc(CCCC2CCCC2)cc1F)c1ccc2c(c1)CCN(Cc1cnn(C3CCC3)c1)C2 +CCOc1ccc(-c2cc3c(ncn3CCCN3CCOCC3)c(C#N)n2)cc1C(F)(F)F +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C(CO)N(C)C +Cn1c(COC(c2ccc(C#N)cc2)c2c[nH]cn2)c(-c2cccc(Cl)c2)cc(C#N)c1=O +COc1nc(Cl)ccc1-c1nccc2cc(S(=O)(=O)Nc3nccs3)ccc12 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)ccc21 +O=C(NCc1ccccc1)c1cnc2nc(NCCc3ccccc3)ccc2c1O +CC1(C)C=C(c2nc3ccccc3[nH]2)CC(C)(C)N1 +Cc1ncccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccco2)cc1 +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2[nH]c(CCc3ccccc3)nc12 +COc1cccc(C#N)c1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 +CC(CO)Nc1ncc2c(n1)CN(C(=O)NC(C)c1ccc(Cl)c(Cl)c1)CC2 +COc1ccc([N+](=O)[O-])cc1CSc1nc2cc(NC(=O)NC(C)(C)C)ccc2n1C1CC1 +CC(C)CC1CC(O)=C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)C(=O)N1Cc1ccc(F)cc1 +CCCCN(C)C(=O)Cc1c(-c2ccccc2)nc2c(Cl)cc(Cl)cn12 +COc1cccc(NC(=O)c2ccc(Nc3ccccc3)c([N+](=O)[O-])c2)c1 +COc1cccc(-c2nc3c(=O)n(C)c(=O)n(C)c3[nH]2)c1 +CNC(=O)c1ccccc1CCC1(O)CCC2=Cc3c(cnn3-c3ccc(F)cc3)CC21C +CCc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)c(C(F)(F)F)c2)cc1C#Cc1cnc2[nH]ncc2c1 +CC1CN(C(=O)C(C)(O)C(F)(F)F)CCN1C(=O)c1ccc(C(=O)c2ccccc2)cc1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCCN(C(C)C)CC3)[nH]c12 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1cccc(O)c1)O2)C(C)=CC(C)(C)N3 +CCN(CC)Cc1ccc(COc2ccc(C(C)=O)cc2)cc1 +CC(=O)c1ccc(NC(=O)CN2CCC(N3C(=O)OCc4ccccc43)CC2)cc1 +O=C(Nc1cccc2cccnc12)c1ccc(N2CC3C4C=CC(C4)C3C2)cc1 +COc1cc2nc(N(C)CCCCCCN(C)C(=O)C3COc4ccccc4O3)nc(N)c2cc1OC +CCC1CN(c2ncc(-c3ncc[nH]3)nc2C)C(C)CN1C1CCN(C(=O)c2ccc(Cl)nc2N)CC1 +O=[N+]([O-])c1ccccc1Nc1nnc(-c2c[nH]c3ccccc23)o1 +NCCCCN(CC1Cc2ccccc2CN1Cc1cccnc1)C1CCCc2cccnc21 +CN1CCc2ccccc2Cc2[nH]c3ccc(O)cc3c2CC1 +NCc1ccc(C(=O)Nc2ccncc2F)cc1-c1cccc(C(=O)Nc2ccc(C(=O)O)cc2)c1 +c1cc(-c2ccc(Cc3ccc(OCC4CCCCN4)cc3)cc2)cs1 +CN(CCCNC(=O)c1cccc2nc3ccccc3nc12)CCCNC(=O)c1cccc2nc3ccccc3nc12 +N#Cc1ccc(Cn2cncc2CN(Cc2cccc(F)c2)c2ccc(N3CCN(C(=O)c4ccc(Cl)s4)CC3)cc2)cc1 +COc1cc(NCc2cccs2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cc(Cn3c(=O)[nH]c(=O)c4ccccc43)cnc2F)C1 +CCOC(=O)N1CCC(c2cc(O)n3nc(C)c(-c4ccc(F)cc4)c3n2)CC1 +Cc1cc(C)cc(Cc2cc(C)ccc2OCCn2ccc(=O)[nH]c2=O)c1 +COC(=O)C(NC(=O)c1cc(-c2ccccc2F)nc2ccccc12)c1ccccc1 +COc1cc(-c2nnc3n2CCCN3Cc2ccc(F)c(F)c2)ccc1-n1cnc(C)c1 +Cc1cc(OC2CN(C(=O)c3nnc(-c4ccccc4)o3)C2)ccc1CN1CC2(CCCO2)C1 +O=C1c2ccccc2C(=O)c2c1c(NCCNCCO)c1ccoc1c2NCCNCCO +CC(c1ccc(Cl)c(F)c1)n1c2c(c3cc(F)cc(S(C)(=O)=O)c31)CCCC2CC(=O)O +O=c1n(-c2ccccc2)nc2c(NCCCc3ccccc3)nc3ccccc3n12 +Cn1cccc1C(=O)N1CCN(C(=O)Nc2ccc(N3CCC(C(=O)N4CCCCC4)CC3)cc2)CC1 +Cc1nc(NC(C)c2cccc(-c3ccc(F)nc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +C[N+](C)(C)Cc1c2n(c3ccccc13)Cc1c(C[N+](C)(C)C)c3ccccc3n1C2 +CC1CC(=O)NN=C1c1ccc2c(c1)C(C)(C)C(=O)N2C +CN(C)c1ccnc2sc3c(=O)n(-c4ccc(C(F)(F)F)cc4)cnc3c12 +COc1cc(Nc2nccc(-c3ccc(N4CCNCC4)nc3)n2)cc(OC)c1OC +CCC(C(=O)NCc1ccc(OC)c(OC)c1)n1nc(C)c2c(C)n(-c3ccc(C)cc3)nc2c1=O +Fc1ccc(C(OC2CC3CCC(C2)N3CCCCc2ccc(N=C=S)cc2)c2ccc(F)cc2)cc1 +CNS(=O)(=O)c1ccc(-n2nc(C(N)=O)c3ccc4[nH]ncc4c32)cc1 +CC1CCC2C(C)C(OCc3ccc(CN4CCN(Cc5ccccc5)CC4)cc3)OC3OC4(C)CCC1C32OO4 +Nc1ncnc2c1ncn2C1OC(C(CSCCC(N)C(=O)O)OP(=O)(O)OP(=O)(O)NP(=O)(O)O)C(O)C1O +CN1C(=O)c2c(nn(Cc3ccc(-c4cccc(F)n4)cc3)c2Cc2ccc(F)cc2)N2C1=NC1CCCC12 +Cc1c(C(=O)C2C(C)(C)C2(C)C)c2ccccc2n1CCN1CCOCC1 +Clc1cc2nc(C3CCCN3c3cc(N4CCCCC4)ncn3)[nH]c2cc1Cl +CNC(=O)C1CCC(NC(=O)c2cnc(-n3ccc4cc(C#N)cnc43)cc2CCC(C)(C)O)CC1 +COc1cccc2c1OC(c1ccc(OCCCN3CCCCC3)cc1)C(C)S2(=O)=O +c1ccc(-c2nc(SCCCn3cccn3)[nH]c2-c2ccccc2)cc1 +Fc1ccc(-c2nn3cc(Cl)ccc3c2-c2ccncc2)cc1 +CCC1CN(c2ncc(C(=O)NC)nc2C)CCN1C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +CC(C)S(=O)(=O)c1ccc2cc1Nc1nc(ncc1Cl)Nc1ccc(N3CCN(C)CC3)c(c1)CC2 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(CC#N)cc4)cc3)cc2n(CCC)c1=O +Cc1onc(C(=O)N2CCN(C(c3ccccc3)c3ccccc3)CC2)c1[N+](=O)[O-] +Fc1ccc(C2CC3CCC(N3)C2COc2ccc3c(c2)OCO3)cc1 +COc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2C2CC2)[nH]1 +Cc1nc(-c2ccc(S(N)(=O)=O)cc2)c(-c2ccccc2)s1 +CCCn1c(=O)c2[nH]c(-c3cc(C)n(CC(=O)Nc4ccc(OC)c(OC)c4)n3)nc2n(CCC)c1=O +Nc1ncc(-c2cc(C3C4CN(C5COC5)CC43)n(CC3CCC3)n2)cc1OC(F)F +CC(=O)OC1CCC2(C)C(CCC3(C)C2C(=O)C=C2C4CC(C)(NC(N)=O)CCC4(C)CCC23C)C1(C)C +C=CCc1c(C(=O)c2c(C)cc(C)cc2C)nc(C)nc1N(CCC)CC1CC1 +CCCCCCCCN=C1SCC2C(O)C(O)C(O)C(O)N12 +COC(=O)C(C)(C)C(c1ccc(Nc2ccccc2)cc1)n1cncn1 +CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)n2nc(-c3ccccc3)cc12 +NC(=O)Nc1cccc2c1C(=O)c1c(C3CCCCC3)n[nH]c1-2 +Cc1c(COc2ccccc2-c2csc(N3CCC4(C(=O)O)CC4C3)n2)ccc2c1CCN(C1CCOCC1)C2 +COc1ccccc1-c1ccc(CC(NC(=O)C2(C)CCCO2)C(=O)O)cc1 +COc1cc(CC(=O)NC(CC(C)C)c2cc(CCC(=O)O)on2)ccc1NC(=O)Nc1ccccc1C +CCOc1cc(C2CC(=O)NC3=C2C(=O)CC(c2cc(OC)ccc2OC)C3)ccc1O +CNC(=O)Cc1ccccc1Oc1nc(Nc2ccc(C(=O)NC3CCN(C)CC3)cc2OC)ncc1C(F)(F)F +CC(=O)NC1C(N)C(CC=Cc2ccc(C)cc2)=C(C(=O)O)OC1C(O)C(O)CO +COc1ccc(OC2CCN(c3nc4cnncc4nc3NC3CC3)CC2)c(F)c1 +CCN1C(=O)C(=Cc2cn(C)c3ccccc23)C(=O)N(CC)C1=S +c1ccc(SCc2nnc(-c3ccc4[nH]cnc4c3)o2)cc1 +Cc1cc2c(OCC(O)CN3CCC(c4cc5cccc(F)c5s4)CC3C)cccc2[nH]1 +FC(F)(Cl)c1nn2cc(-c3cc4ccccc4o3)nc2s1 +Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)CCC(=O)O)O2)c(=O)[nH]c1=O +O=C(NC(=S)Nc1ccc(F)cc1)c1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +CCCC1CC(=O)C2=C(C1)NC(C)=C(C(=O)OCC)C2c1ccc(C(C)(C)C)cc1 +CC1CC(N)CN(c2ccncc2NC(=O)c2csc(C3CCCCC3)n2)C1 +Cc1ccnc2c1C(=NN=C(N)N)CC(c1sccc1Cl)C2 +CCc1ccc(C2CC(NC(=O)c3ccc(-c4cccc(C(F)(F)F)c4)cn3)CN(C(=O)C3CCCC3)C2)cc1 +C=C(c1ccc([Se]C)cc1)c1cc(OC)c(OC)c(OC)c1 +Nc1ncnc2c1nc(Sc1cc3c(cc1Br)OCO3)n2CCC1CCCCN1C=O +COCCNc1nc2ccc(C#CC3(O)CCCCC3)cc2n1-c1ccnc(N)n1 +CNC(=O)c1cc(Oc2ccc3oc(Nc4ccc(Cl)c(CN5CCOCC5)c4)nc3c2)ccn1 +COc1cc2ncnc(N3CCN(C(=O)Nc4ccc(C(C)C)cc4)CC3)c2cc1OC +N#Cc1nccc(N2CC(S(=O)(=O)c3ccccc3C(F)(F)F)CC2C(=O)N2CCC2)n1 +CCc1cnc(NC2CCC(NC(=O)c3ccc(F)c(F)c3)CC2)nc1N(C)C +COc1cncc(-c2ccc3c(c2)C2(COC(N)=N2)c2cc(OCC(C)(C)C)ccc2O3)c1 +CCCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccc(F)cc2OC)cc1 +Nc1nc(N)c2nc(CN3CCSc4cc(C(=O)NC(CCC(=O)O)C(=O)O)ccc43)cnc2n1 +C(=C1CCCN=C1c1cccnc1)c1cc2ccccc2o1 +Cc1ccc(NCC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)nc1 +Cc1ccc(NC(=O)c2ccsc2)cc1Nc1ccc2c(c1)CCCCC2=O +N#CC1CC2CCCC2N1C(=O)CC(N)Cc1ccc(F)cc1 +O=C(NC1N=C(c2ccccc2)c2ccccc2NC1=O)c1cccc(Cl)c1 +CCCCCn1c(NC(=O)c2cccc(C#N)c2)nc2cc(C(=O)N3CCCCC3)cnc21 +CC1(C)c2[nH]nc(NC(=O)c3ccccc3)c2CN1C(=O)N1CCN2CCCC2C1 +CCOc1ccc(S(=O)(=O)N(CC(=O)N2Cc3ccccc3CC2C(N)=O)c2ccc(OC)cc2)cc1 +COc1ccc(COc2ccc(C=C3SC(=O)NC3=O)cc2)cc1 +COc1ccc(-c2cc(-c3ccnn3CC(F)(F)F)c3c(N)ncnn23)cc1N1CCOC(C)(C)C1=O +Cc1ccc(-n2nc(C3CCN(CC(F)(F)F)CC3)cc2NC(=O)c2cnn3cccnc23)cc1 +CC(NC(=O)Nc1cc2[nH]nc(NC3CCCCC3)c2cn1)c1ccccc1 +COc1ccc(C(C(=O)NCCC(c2ccccc2)c2ccccc2)c2ccccc2)cc1 +CNC(=O)c1c(N)n(C2CCOCC2)c2nc(C#CC(C)(O)COC)ccc2c1=O +O=C(O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3C3CC3)n3c2CCCC3)c(F)c1 +COc1cc(N2CCN(C(=O)c3ccccn3)CC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +O=C(c1cnccc1Oc1ccccc1)N1CCN(C2CC2)c2ccccc21 +CC(C)=CCCC(C)=CCCC(C)=CCCP(=O)(O)CP(=O)(O)O +N#Cc1cc(S(=O)(=O)Nc2cscn2)ccc1Oc1ccc(C(F)(F)F)cc1-c1ccnn1C1CNC1 +CN1C2COCC1CC(OC(=O)c1cn(-c3cn[nH]c3)c3ccccc13)C2 +CCCCCCCCCCCCOC(=O)c1cc(O)c(O)c(O)c1 +Cc1ccc(S(=O)(=O)Nn2c(=S)[nH]c3ccc(F)cc3c2=O)cc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)NCCCCc1[nH]c(=O)cnc1C +Cn1c2ccccc2c2nnc(SCCCn3c(=O)[nH]c4ccccc43)nc21 +CCCCN(CC)CCNC(=O)C1c2ccccc2C(=O)N(Cc2ccc(F)cc2)C1c1ccc(OC)cc1 +COc1ccc(Cl)c(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)c1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(C(C)CNCc3ccccc3C)c2=O)c1F +CC1(C)OCC2=NC3=C(C(=O)COC3)C(c3ccc(F)c(Br)c3)C2=C1O +COC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc(C23CC4CC(CC(C4)C2)C3)c2ccccc2n1 +c1ccc(-c2nnc3c4c(c(OCc5ncccn5)nn23)C2CCC4CC2)cc1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(C3CC4CN(C(=O)c5ncco5)CC4C3)nc21 +CCCCc1ccc(C(=O)c2c(C)n(CCC)c3ccccc23)c2ccccc12 +N#Cc1cccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3nc4c(s3)CC(N)CC4)c2)c1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCCF)s4)nc23)N1 +CC(C)(C)n1cc(-c2cc(CO)c3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cn1 +CNc1cccc(CNCC2(F)CCN(C(=O)c3ccc(F)c(Cl)c3)CC2)n1 +Cc1cc(-c2cnc(C(C)Nc3nccc(N4C(=O)OCC4C(C)O)n3)nc2)ccc1Cl +O=C1c2cc(N3CCCC3)ccc2NC(Cc2ccccc2)N1c1ccc(O)cc1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCCC(=O)N1CCN(C)CC1 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccncc2[nH]1)C1CCCC1 +C=CC[n+]1ccc2c(c1)[nH]c1ccc(Cl)cc12 +COc1ccc2ccc(CC(O)C=CC3CCC(=O)C3CCc3ccc(C(=O)O)cc3)cc2c1 +CCC12CC(O)C(c3ccccc3)CC1CCc1cc(O)ccc12 +NC1(Cc2c(Cl)cccc2Cl)CCN(c2ncnc3[nH]ccc23)CC1 +Cc1onc(-c2ccccc2Cl)c1C(=O)Nc1sc2c(c1C#N)CCC2 +NS(=O)(=O)Nc1cncc(-c2nc(NCc3ccccn3)c3c(-c4ccccc4)cccc3n2)c1 +C#CCOC(=O)CC1C(C(=O)OCC#C)=C(N)Oc2ccc(-c3ccc(N)cc3)cc21 +COc1cc(N)c(Cl)cc1C(=O)NCC1CCN(CCCn2nccn2)CC1 +O=C1N(Cc2c[nH]c3ccccc23)CCCC12CCN(c1nc3cc(Cl)ccc3o1)CC2 +O=C(NC1CCC(CNc2cncc(F)c2)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1nn(C2CCOCC2)c2sc(C(=O)Nc3ccc(N4CCC(O)CC4)c(F)c3)cc12 +CCN(CC)CCCCNc1nnc(-c2ccc(NC(=O)c3ccccc3F)cc2)o1 +Cc1cc(=O)n(-c2ccc(Cl)cc2Cl)nc1C(=O)Nc1ccc(Oc2ccnc3c2ccn3C)cc1 +Cc1cn(CC(N)C(=O)O)c(=O)n(Cc2cc(-c3ccccc3)sc2C(=O)O)c1=O +CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)c1c(-c2ccc(F)cc2)c2ccccc2c(=O)n1C +Cc1cnc(C(=O)CCN(Cc2ccccc2)C(C)C)s1 +Cc1cccc(Nc2ncnc3ccc(NC(=S)NCc4ccccc4)cc23)c1 +CCCCn1c(=O)c2c(ncn2S(=O)(=O)c2cc(C)c(Cl)cc2C)n(CCCC)c1=O 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+CCN(CC)CCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)cc3)c2s1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccn(Cc2ccc(Cl)cc2)c(=O)c1 +O=C(O)CCCC=CCC1C(NS(=O)(=O)c2ccccc2)CC2CC21 +COC(=O)Cc1cccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)c1 +N#CC1(NC(=O)C(Cc2ccc(Cl)c(Cl)c2)NC(=O)c2cnn(C3CCC3)n2)CC1 +CC(C)CC(NC(=O)c1cc[nH]n1)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1 +COCc1nnc(N2CC(Oc3ccc(F)cc3C)C2)n1-c1ccc(OC)nc1 +Oc1ccc(Nc2ccnc3cc(Cl)ccc23)cc1CN1CCN(c2nc3ccccc3s2)CC1 +CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nccn5c4)c3c2)CCC1C1CC1 +CC(C)=CCCC(C)=CCCC(C)=CCN=CN(C)CCC=C(C)CCC=C(C)C +C=CC(=O)Nc1cccc(Oc2ncnc3[nH]cc(-c4cccnc4)c23)c1 +CCn1cc(-c2cc3c(-c4cc(C)ccn4)n[nH]c3cn2)cn1 +Cc1ccc(NC2=C(c3ccc(C(F)(F)F)cc3)C(=O)c3ccccc32)cc1F +COc1ccccc1N1CCN(CCCCn2cnc3c(cnc4ccc(C)cc43)c2=O)CC1 +CC(C)C(N)c1cccc(F)c1N1CCN(C(=O)C2CN(C(=O)C3CC3)CC2c2ccc(Cl)cc2)CC1 +CC(C)(C)C(=O)Nc1ccc(NC(=O)c2cccc(O)c2)nc1 +O=C(NCCCCCCCCNC(=O)NS(=O)(=O)c1cccc(Cl)c1)NS(=O)(=O)c1cccc(Cl)c1 +Cc1cccc(NC(=O)CSc2nnc(-c3ccoc3C)n2Cc2ccco2)c1 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+COc1ccc([N+](=O)[O-])cc1OCC1CN(Cc2ccc(Cl)cc2)CCO1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCNC13CC4CC(C)(CC(C)(C4)C1)C3)C2 +Fc1cccc(F)c1CNc1ncc(Oc2ccccc2C(F)(F)F)cn1 +Cc1noc(C)c1Cn1cc(N2C(=O)NC(=Cc3ccccc3)C2=O)cn1 +COc1cc(-c2ccc(C=CC(=O)O)cc2)cc(C23CC4CC(CC(C4)C2)C3)c1OC +O=C(O)c1ccc(S(=O)(=O)N(c2ncc3ccccc3c2C2CC2)C2CCc3cc(OC(F)(F)F)ccc32)cc1 +CCN(CC)CCOC(=O)c1ccccc1Sc1ccc(Cl)cc1 +Cc1noc(C)c1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C(F)(F)F)cc1 +COc1ccc(C(=O)Nc2ccc(OCCN(C)C)cc2)cc1Nc1nccc(-c2cccnc2)n1 +Cn1ncnc1-c1cc(F)ccc1CNC(=O)c1nc(C2CCOC2)n(C)c(=O)c1O +Nc1nc(-c2ccccc2)cc(-c2cccc(Cl)c2)n1 +CCN(CC)CCOc1ccc(N2C(=O)C(=Nc3cccc(C(F)(F)F)c3)c3ccccc32)cc1 +O=S(=O)(C1=CC=C=C=C1)n1cc2c3c(cccc31)N1CCNCC1C2 +Cc1cccc2c(C3=C(c4c[nH]c5ccccc45)C(=O)NC3=O)nc(N3CCN(C)CC3)nc12 +CCC(COc1cccc(OC)c1)OC(=O)NCc1ccccc1 +Cc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)N(C(C)C)C(C)C +CC(C)(C)c1ccc(-c2noc(-c3ccc4c(c3)CCO4)n2)cc1 +O=C(Nc1ccc(Cl)c(C(=O)N2CCCCC2)c1O)Nc1cccc(F)c1Cl 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+O=C(O)C1Nc2cc(Cl)cc(Cl)c2S(=O)(=O)N1Cc1cccc(F)c1 +COc1ccccc1N1CCN(CCCSc2nc3sc(C)c(C)c3c(=O)n2C)CC1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)Oc1cccc(-c2ccccc2)c1 +Cc1nc(-c2cccc(CN3C(=O)CCCC3c3cccc4c3OCCO4)c2)cs1 +Cc1nc(NCc2ccccc2F)cc(-c2ccc3ncsc3c2)n1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCCOc3ccccc3)[nH]c3ccc(Cl)c(F)c23)c1 +CN(C(=O)C(Cc1ccc(C(N)NN)cc1)NS(=O)(=O)c1ccc2ccccc2c1)C1CC1 +COC(=O)C1CC2CC1CN2CCOc1ccc(Cc2ccccc2)cc1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(nnc2-c2cnccn2)C1 +Cc1nsc(-c2ccc(N3CCN(c4ccccc4C(F)(F)F)CC3)nn2)n1 +O=C1NC(=O)c2c1c1c3cccc(O)c3[nH]c1c1c2c2cccc(O)c2n1C1OC(CO)C(O)C(O)C1O +Cc1cc(SC2=C(O)OC(C)(CCc3ccc(O)cc3)CC2=O)c(C(C)(C)C)cc1O +Cc1csc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cc2)c1Cl +O=C(NCCN1CCC2(CC1)C(=O)NCN2c1cccc(F)c1)c1ccc(Br)cc1 +C=CCc1cccc(C=NNC(=O)CN2CCN(Cc3ccc(F)cc3)CC2)c1O +COc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(F)F)nn12 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1c(-c2c(Cl)cccc2Cl)noc1C +CC(=O)C(=Nc1cccc(F)c1)NNc1ccccc1C(F)(F)F +COc1ccc(Br)cc1CCc1c(F)cccc1C(=O)N=C(N)NCC(C)C +O=C(O)c1ccccc1NC(=O)N1CC2C=C(c3ccccc3C(F)(F)F)CC2C1 +N=C(N)c1ccc2[nH]c(-c3cccc(-c4cc(CNC(N)=O)ccc4O)c3O)nc2c1 +COc1ccc(CC(C)(C)NCC(O)COc2ccc(-c3nc(-c4cccs4)c[nH]3)cc2)cc1OC +O=C(Cc1cccc(Cl)c1)NCCCNc1nc2ccccc2[nH]1 +Cc1cccc(Cl)c1Nc1nc2cc(N3CCOCC3)ccc2n2cncc12 +CC(=O)N1CCC(n2cnc3ccc(-c4cccc(OCC(O)CN5CCc6ccccc6C5)c4)cc32)CC1 +O=C(NCC(=O)N1CCC(NC2CCC(O)(c3ccc(-c4ccncc4)cn3)CC2)C1)c1cccc(C(F)(F)F)c1 +CCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +Cc1ccc(C)c(NC(S)=NCC(c2ccccc2)N(C)C)c1 +Cc1cc(-c2cc(C(F)(F)F)nn2-c2ccc(S(C)(=O)=O)cn2)ccc1-c1ccco1 +Cn1cc(NS(=O)(=O)c2c(Cl)cc(-c3ccnc(N4CCNCC4)c3)cc2Cl)cn1 +Cc1[nH]c2ccccc2c1CC(=O)Nc1cncc(C(=O)c2cn(C(C)C)c3ncncc23)c1 +CC(C)(C)NC(=O)C1CCCN1C(=O)C(=O)C(Cc1ccccc1)NC(=O)OCc1ccccc1 +COc1ccccc1CN(C)C(=O)c1cc(-c2n[nH]c(=O)n2-c2ccccc2C)c(O)cc1O +CCN(CC(C)O)c1ccc(Br)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12 +O=C(N1CCc2ccccc21)C12CC3CC(CC(O)(C3)C1)C2 +COc1c(C)cc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1Cl +CCCCCS(=O)(=O)NC(=O)C(C)=Cc1ccc(OCCOC)cc1Oc1ncc(C(F)(F)F)cc1Cl +CC(C)Oc1cc2c(-c3cc(N4CCC(N(C)C)C4)ncn3)n[nH]c2cc1F +CCCCN1CCCC1CNC(=O)c1c(O)c(Cl)cc(Cl)c1OC +NC(=O)c1cnc(NC2CCCNC2)c2nc(-c3ccc4ccccc4c3)cn12 +O=C(c1ccc(Cl)cc1Cl)N1CCc2c(nnn2-c2ncccn2)C1 +CCCN(CCC)C(=O)c1cc(C(=O)NC(Cc2cc(F)cc(F)c2)C(O)CNCc2cccc(OC)c2)cc(C(C)N)c1 +CC(C)n1c(=O)c(C(=O)NC2CC3CCC(C2)N3CCCCCCCCS(=O)(=O)O)cc2ccccc21 +COc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cc1C(C)O +O=C(NC1CCNC1)c1cn2ccnc2c(N2CCN(c3ccccn3)CC2)n1 +O=S(=O)(Nc1cc(Sc2nc[nH]n2)c(O)c2ccccc12)c1ccc(Br)cc1 +COc1ccc(S(=O)(=O)C(CC(=O)NO)c2cccc(OCc3ccccc3)c2)cc1OC1CCCC1 +Cn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(Cl)c2)CC3)n1 +COc1ccc(C(O)c2ccnc(Nc3ccc(C#N)cc3)n2)cc1 +CC(C)(COc1ccc(-c2ccc(-c3ncc(C4CCCCC4)[nH]3)cn2)cc1)C(=O)O +Cn1nc(C(C)(C)C)cc1NC(=O)Nc1cccc(-c2ccccc2)c1 +CS(=O)(=O)c1ccc2nc(NC(=O)NCc3nc(-c4ccccc4)c[nH]3)sc2c1 +Cc1ccc(-c2cc(C(=O)NC(C)CN3CCOCC3)cc(-c3scnc3C)c2)cc1 +CNC(C)C(=O)Nc1cc(-c2ccncc2)c(-c2cncnc2)c(C#Cc2ccccc2)n1 +FC(F)(F)c1ccccc1Cn1nnc2c(NC3CC3)nc(-c3ccccc3)nc21 +CC(=O)Nc1cccc(N2CCN(CCCCNS(=O)(=O)c3ccc(C)cc3)CC2)c1 +Cc1ncncc1-c1cc(C(=O)Nc2ccc(OC(F)(F)Cl)cc2)ccc1N1CC(O)C(O)C1 +COc1cc2c(cc1OC)CN(Cc1ccc(OC)c3oc(-c4ccccn4)cc13)CC2 +CCc1ccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CC(C)N(C4CCOCC4)CC2C)C3(C)C)nc1 +CN(C)CCNC(=O)c1cccc2ccc(-c3ccc(Br)cc3)nc12 +N#Cc1ccc(Cc2ccc3c(NCCCNCc4ccco4)ccnc3c2)cc1 +O=C(O)c1cncc(-c2ccc(N3CCC(Oc4cc(F)ccc4Br)CC3)nc2)c1 +O=C(O)CSc1ncnc2c(C3CC3)c(C(F)(F)F)sc12 +O=c1cc(N2CCOCC2)oc2c3c(ccc12)CCCC3 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1C(=O)Nc1cnc(NC2CCN(C)CC2)nc1 +Cc1nonc1C(=O)Nc1n[nH]c2c1CN(C(=O)N1CC(C)N(CC3CCOCC3)CC1C)C2(C)C +COc1ccc2[nH]cc(CCn3cc(NC(=O)c4ncsc4-c4cccc(C)c4)cn3)c2c1 +Cc1nnc(-c2cc(C(=O)N3CCC(c4ccc(C#N)cc4)CC3)c(C)cc2N(C)C)[nH]1 +CC(C(=O)N1CCc2cc(OCc3ccccc3)ccc2C1C(=O)NCCN(C(C)C)C(C)C)c1ccccc1 +Clc1cccc(COc2nc(N3CCNCC3)nc3[nH]cnc23)c1 +Cc1ccc(-n2nc(C3CCN(CC(N)=O)CC3)cc2NC(=O)c2cnn3cc(Br)cnc23)cc1 +CCc1cnc(Nc2cccc(S(N)(=O)=O)c2)nc1-c1sc(NC)nc1C +CN(c1ncnc2[nH]ccc12)C1CC(CS(=O)(=O)c2ccccc2)C1 +NC(=O)N1CCC(n2c(=O)cnc3cnc4ccc(-c5ccc(N)nc5)cc4c32)CC1 +NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ncnc3ccccc23)CC1 +O=C1NCC(c2ccc(C(F)(F)F)cc2)C12CCN(C1(c3ccc(F)cc3)CCCCC1)CC2 +O=C(O)C=Cc1ccc(Oc2c(-c3ccccc3)c(C3CC3)cc3cc(O)ccc23)cc1 +CN(c1ccccc1C(=O)NO)S(=O)(=O)c1ccc(Oc2ccncc2)cc1 +O=C(OC1CC2(N3CCCCC3)CC(c3ccccc3)C1C(c1ccccc1)C2)c1cccnc1 +CCCCC1OC2(CCCC3=Cc4c(cnn4-c4ccc(F)cc4)CC32C)OC1CCCC +COc1nc(-c2ccccc2F)cc2nc(-c3c(Cl)c(C(C)(C)C)nn3C)[nH]c12 +CCc1ccc2c(c1)C(C(S)=NC)=CC(C)(C)O2 +NC(Cc1ccccc1)C(=O)N1Cc2ccccc2CC1c1nc(-c2ccccc2)c[nH]1 +CNCc1cc(-c2ccccc2C#N)n(S(=O)(=O)c2cccnc2)c1 +CC(=O)c1cccc(NC(=O)NCCCC2CC(Cc3ccc(F)cc3)CCN2C)c1 +O=C(c1n[nH]c2c1CCN(CC1CC1)C2)N1CCC(c2cccc(F)c2Cl)CC1 +COc1cc(Cn2c(N)nc3cc(-c4cnn(C)c4)cnc32)ccc1OCc1ccc(C(F)(F)F)nc1 +Cc1cc(NC(=O)c2ccc(CO)cc2)nn1Cc1cc(Cl)ccc1OCC(C)C +O=C(NCc1cccnc1)Nc1ccc(S(=O)(=O)N2C3CCC2COC3)cc1 +Cc1cc(COc2ccc(C(=O)NC3CN(S(C)(=O)=O)CC3C(=O)NO)cc2)c2ccccc2n1 +FC(F)(F)c1cccc(-c2[nH]c(N3CCN(c4ncccc4C(F)(F)F)CC3)nc2-c2ccccc2)c1 +O=C(CCc1cnn(-c2ccccc2)c1)Nc1ccccc1C(=O)O +Cc1ccn2c(C(=O)Nc3cc(-c4noc(C5CC(O)(C(F)(F)F)C5)n4)ccc3C)cnc2c1 +Cc1n[nH]c(C)c1CCCOc1cc(C(=O)O)ccc1F +O=C(O)C1CC2CC(Oc3cc(-c4cccs4)ccc3-c3nnn[nH]3)CCC2CN1 +Nc1ncnc2cc(CN3C(=O)CN(S(=O)(=O)c4cc5ccc(Cl)cc5s4)CC3C(=O)O)ccc12 +COc1ccc(NC(=O)COc2ccc(C=C3N=C(c4ccccc4)N(c4ccc(OC)cc4)C3=O)cc2)cc1 +Cc1nn(C)c2nnc(Nc3ccc(S(=O)(=O)NCCO)cc3)nc12 +Cc1cc2c(Cl)cccc2nc1N(Cc1ccc(OC(F)(F)F)cc1)S(=O)(=O)c1ccc(C(=O)O)cc1 +O=[N+]([O-])c1ccc(O)c(C=NNc2ccccn2)c1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCCCC1CNCCCc1ccccc1 +Cc1ccc(OCCNC(=O)C(CC(=O)O)NC(=O)CCCOc2ccc(C(=N)N)cc2)cc1C +COc1cc2nccc(Oc3ccc(Nc4ccc(C(C)C)cc4)cc3)c2cc1OC +CC(=O)Nc1nc2ccc(-c3ccnc(Cc4ccccc4)n3)cc2s1 +CC(C)(C)c1ccc(NC(=O)N2Cc3ccc(S(=O)(=O)Nc4ccc(OCCCC5CCCCC5)cc4F)cc3C2)cc1 +COc1ccccc1NC(=O)c1ccc(-c2cc(-c3nnc(C)o3)ccc2C)cc1 +O=C1NC(Nc2ccccc2)=NC1=Cc1ccc2c(c1)OCO2 +N#CCNC(=O)c1cccc(-c2ccnc(Nc3ccc(N4CCOCC4)cc3)n2)c1 +NC(=S)NN=Cc1ccc(-c2ccc(SC(F)F)cc2)o1 +C=C(Br)C(=O)Nc1cccc(C=CC(=O)Nc2ccc(Cl)cc2)c1 +COC(=O)C(NC(=O)Nc1cc2[nH]nc(OC)c2c(CO)n1)c1ccccn1 +CCc1cc(OCc2ccc(-c3ccccc3-c3nn[nH]n3)c(Cl)c2)c2c(n1)CCCC2 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(OCC4(C)CC4)ncc3F)C2)cc1 +Cc1ccccc1CN(c1ccc(C#N)c(Cl)c1)C1CCN(S(C)(=O)=O)C1 +COc1c(CN2CCC(C(=O)NC(C)(C)C)CC2)cccc1NC(=O)c1ccc(F)cc1 +CCn1c2ccccc2c2c3c(c4c5ccccc5n(CC)c4c21)C(=O)NC3 +COc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C)nc2C(C)O)n1 +O=C(O)CN1C(=O)C(NC(=O)C(S)Cc2ccccc2)CSc2ccccc21 +Cc1c[nH]c2c(-c3c(F)cc4c(c3F)C(=NOC(C)C)CC(C)(C)N4)cccc12 +Cc1ccc(C(=O)NC2(C(=O)NC(C)c3ccc(-n4nc(Cl)c5ccccc54)cc3F)CC2)cn1 +CC(=O)OC1CC2CCC1C(N(C)C)C2c1ccccc1 +COc1cccc(N2CCN(CCCn3cnc4c(cnc5ccccc54)c3=O)CC2)c1 +O=c1[nH]c(=O)n(COC(CO)CO)cc1Cc1cccc(Oc2cccc(Cl)c2)c1 +CCCCCCCCCCCC(=O)OC1=C(C)C2(OCCO2)C(=O)C2=C1N1CC3NC3C1(OC)C2COC(N)=O +CCc1ncnc(-c2ccc(C(=O)N3CCC(N4CCC(C)CC4)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +C=CC(=O)Nc1cccc(-n2c(=O)cc(C)c3cnc(Nc4ccc(N5CCN(C)CC5)cc4C)nc32)c1 +CC(c1c(F)cc2ncc(-c3cnn(C)c3)cc2c1F)n1nnc2ncc(-c3cnn(CCO)c3)nc21 +CNCC(=O)Nc1ccc(S(=O)(=O)N=c2sc(S(N)(=O)=O)nn2C)cc1 +CC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3cccc(Br)n3)c2)CC1 +Cc1cc(C)c2ccn(-c3ccc(C(C)C)cc3Br)c2n1 +Oc1ccc2[nH]c(-c3ccccc3)nc2c1CNC1CCCC1 +COc1ccc(C2CC(=O)C3=C(C2)NC(C)=C(C(=O)OC2CCCC2)C3c2ccccc2F)cc1OC +COc1ccc(-c2cnc(C(=O)N3CCCC3)o2)cc1S(N)(=O)=O +CNc1ccc(C=Cc2ccc(OCCCCCCCCCCF)cc2)cc1 +Nc1ncnc2c1c(COc1cccc(Cl)c1)nn2C1CCOCC1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2cc(CC(C)C)sc2S(=O)(=O)NC(=O)OCCC2CCCC2)cc1 +COC(=O)c1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3ccccc3n(CCC(C)C)c1=O)N2 +Nc1cc(C(=O)N2CCCC2)cn2nc(-c3ccccn3)nc12 +CCOc1cc(F)c(Cn2nc(-c3ncc(OCC4(CO)COC4)c(Nc4ccncc4)n3)c3c2CCC3)c(F)c1 +N#Cc1cnc2sc(C=CC(=O)N3CCCC3)cc2c1Nc1ccc2[nH]ccc2c1 +CCC(O)(c1nnnn1Cc1ccc2c(-c3ccc(F)cc3)cc(C(N)=O)nc2c1)C(F)(F)F +CC(O)C(NC(=O)c1ccc(OCc2ccccc2)cc1)C(=O)NC(CCc1ccccc1)C(=O)NCc1cccc(Cl)c1 +CNC(=O)C(NC(=O)C(CCCc1ccccc1)C(C)N(O)C=O)C(C)(C)C +Cc1cc(-c2nc(C(F)(F)F)cn2-c2ccc(S(C)(=O)=O)cc2)ccc1F +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCCCCCCCC(=O)O)C(=O)O)cc1 +CC(=Cc1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CO2 +O=C(O)c1c(NS(=O)(=O)c2ccccc2NCCC2CCCN2C2CCCCC2)ccc2c1CCCC2 +Fc1ccccc1-c1c[nH]c(C2Cc3c([nH]c4ccccc34)C(C3CCOCC3)N2)n1 +Nc1ncc(C2=CCOCC2)nc1-c1ccc(C(=O)NC(CO)c2cccc(Cl)c2)c(F)c1 +CNc1c2ccccc2nc2cccc([N+](=O)[O-])c12 +C[N+](C)(Cc1ccc(I)cc1)CC1C2CC3CC(C2)CC1C3 +Cc1cc(C(=O)N2CCN(C)CC2)ccc1NC(=O)c1csc2c(=O)[nH]cnc12 +CCCCc1ccc(C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(C=C2SC(c3cccnc3)=NC2=O)cc1 +CC1CCC(N2CCC3(CN(C(=O)c4cc5ccccc5[nH]4)c4ccccc43)C2)CN1 +CN(C)CCNC(=O)c1cccc2ccc(-c3ccncc3)nc12 +Cc1cc2nc(C(CNC(=O)c3ccc(-n4cnnc4)cc3Cl)c3ccccc3)[nH]c2cc1C +CCCN(CCC1(O)CC(NC(=O)c2ccc3ccccc3c2)C1)C1CC1c1ccccc1Cl +O=C1COC(c2ccc(-c3cc4c(cc3Cl)NCC4C(=O)O)cc2)CN1 +Nc1nc(Nc2ccc(S(N)(=O)=O)cc2)nn1C(=O)c1cccs1 +Cc1ccc(S(=O)(=O)N(CCN=[N+]=[N-])C(C(=O)NO)C(C)C)cc1 +Fc1cc(C(F)(F)F)cc2c1NC(c1ccccc1)C1CCCOC21 +N=C(N)c1ccc(COc2ccccc2OCc2ccc(C(=N)N)cc2)cc1 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+Fc1ccc(-c2nc3n(c2-c2ccncc2)CCS3)cc1 +O=C(O)COc1ccc(C=Cc2n[nH]c(-c3ccccc3O)n2)cc1 +C#Cc1cc(-c2ccc(O)c(F)c2)nc2ccc(O)cc12 +CCCCc1ncc(C=C(Cc2cccs2)C(=O)O)n1Cc1ccc([N+](=O)[O-])cc1 +O=c1c2cn[nH]c2c2ccc(-c3ccccc3CN3CCCNCC3)cc2n1CC(F)(F)F +Cc1ccc(NC(=O)Nc2ccc(-c3csc4ccnc(N)c34)cc2)cc1 +CC(C)Nc1ncc2nc(Nc3c(F)cc(F)cc3F)n(C3CCC(C(=O)NC4CC4)CC3)c2n1 +Fc1ccc(-c2[nH]c3nc(NCc4ccccc4)ccc3c2-c2ccncc2)cc1 +COc1ccc(CNc2cc(OCC3CC3c3ccc(OC)cn3)nn(C)c2=O)cc1 +Cc1cccc(-c2ocnc2C(=O)Nc2cnn(CCn3ccc4cc(Cl)ccc43)c2)c1 +O=S(=O)(NCB(O)O)c1cc2c(Cl)ccc(Cl)c2s1 +COc1ccccc1N1CCN(CC(O)CCNC(=O)c2cc3cc(I)ccc3[nH]2)CC1 +O=S1(=O)c2cccc3cccc(c23)N1CCCN1CCN(c2cccc(F)c2)CC1 +C[S+]([O-])C=Cc1ccc(-c2cnc(C(=O)CCCCCCc3ccccc3)o2)nc1 +Clc1cccc(CCNc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)c1 +CN1CCN(c2ccc(Nc3ncc4c5ccccc5n(C5CCCC5)c4n3)nc2)CC1 +COc1cc(N2CCC(Oc3ccc(N4N=C(C(F)(F)F)C(C)C4CC(=O)O)cc3)CC2)c(Cl)cn1 +COc1ccc(S(=O)(=O)NC2CCCCN(CC(=O)CC3CCN(C(=N)N)CC3)C2=O)cc1OC +O=C(c1ccncc1)c1cc(Br)ccc1NS(=O)(=O)c1ccc(OC(F)(F)F)cc1 +O=C(c1ccc(C(=O)N2CCC(N3CCC3)CC2)cc1)N1CCC(N2CCC2)CC1 +CNc1ncc(-c2cc3c(n2C(C)C)C(c2ccc(C#N)cc2)N(c2cc(Cl)c(=O)n(C)c2)C3=O)c(OC)n1 +CN(C)C(=O)CC1CNC(C(=O)N2CCCC2C#N)C1 +N=C(N)c1ccc(OC(=O)c2ccc(CC3(C(=O)NC(CC(=O)O)C(=O)O)CCCC3)s2)c(F)c1 +O=C(CN1CCN(Cc2ccc(Cl)cc2)CC1)N1CCc2ccc(Cl)cc21 +N=C(N)Nc1cccc(C(=O)NNC(=O)CC(CC(=O)O)c2cc(Cl)cc(Cl)c2)c1 +N=C(NCc1cc(F)cc(F)c1)c1ccc(OC(F)(F)F)cc1 +Cc1ccc2c(-c3ccnc(Nc4ccccc4)n3)c(-c3ccc(F)cc3)nn2n1 +CS(=O)(=O)c1ccc(CSc2nc(-c3ccc(Br)cc3)c(-c3ccncc3)[nH]2)cc1 +COc1cccc(NC(=O)NC2CCCCC2CN2CCC(Cc3ccc(F)cc3)CC2)c1 +O=C(CCCCCC1NC(=O)C2CCCN2C(=O)C2CCOCCCCOCCC(NC1=O)C(=O)N2)NO +CCCOCC1(O)CC2CN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1 +CCCCNc1nn2c(-c3ccccc3)nnc2c2ccccc12 +COc1c(C(=O)CCc2ccccc2)c(O)c(OC)c2occc12 +OC1CCCC1n1c2cnccc2c2cnc(Nc3ccc(N4CCNCC4)nn3)nc21 +CNC(=O)c1c(NC(=O)c2nc(N3CCC3)cnc2Nc2cncnc2)cnn1C +CSc1ncc2cc(-c3ccccc3)c(-c3ccc(CNCCc4nc[nH]n4)cc3)nc2n1 +COc1cccc(-c2nc3c(oc4ccc(Br)cc43)c(=O)[nH]2)c1Cl +COc1cccc2c1CCC1C2CCCN1C(=O)c1cn(C)c2ccccc12 +CCCCCCCCC=CCCCCCCCC(=O)OCC(COP(O)(O)=S)OC +COc1ccc(C(=O)N2CCN(C(=NC#N)Nc3cccc4ncccc34)CC2c2ccccc2)cc1OC +C#Cc1cccc(Nc2ncnc3cc(OCCOC)c(NC(=O)C=CCN(C)C)cc23)c1 +N#CCC(=O)N(CC#N)CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(Nc1ccc2c(c1F)CCC(F)(F)C2O)c1cc2cc(Cl)ccc2[nH]1 +COc1ccc(S(=O)(=O)N2Cc3ccccc3CC2C(=O)NC(CCCN=C(N)N)C(=O)O)cc1OC +CCCOc1ccc2c(c1OC)CCN(Cc1ccc(C(C)NC(C)=O)cc1)C2 +O=C1N=C(NCCc2cccc(F)c2)SC1=Cc1ccc2ncccc2c1 +CC(NC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1)c1cncnc1 +CC(C)CNc1nc(C#CCN)cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc12 +COC1C(F)CN(C(=O)Cn2nc(C(N)=O)c3cnccc32)C1C(=O)NC(C)c1cccc(Cl)c1F +CCCCCCCNCC(OC1OC(CN)C(O)C1O)C1CC(O)C(n2ccc(=O)[nH]c2=O)O1 +COC(=O)c1ccc2sc3c(=O)n(CCN4CC5CCc6c(OC)cccc6C5C4)c(=O)[nH]c3c2c1 +CC(C)OC(=O)N(C)CC(Nc1ncnc2c1=CCCC=2C(N)=O)c1cccc(NC(=O)c2ccc(Br)cc2)c1 +CC(C)(O)Cn1cc(-c2cnc3nnn(Cc4ccc5ncccc5c4)c3n2)cn1 +Cc1cc2c(NC(=O)NC3CC(C)(C)Oc4cc(F)ccc43)cccc2cn1 +Clc1ccc(N2CCN3CC2CCC3C(c2ccccc2)c2ccccc2)cc1Cl +COC(=O)N1CCC(O)(Cc2cccc(C(CC#N)Nc3nc4nc(C)ccc4[nH]3)c2)CC1 +CCCCc1ccc2[nH]c(-c3ccc(CC)cc3)c(C=C(C#N)C#N)c2c1 +CS(=O)(=O)Oc1ccc2c(c1)CCC1C2CCN1CCCCNC(=O)c1ccc(-c2ccccc2)cc1 +NC(=O)c1cccc(-c2cc(OC(=O)NC3CCCCC3)ccc2OS(=O)(=O)O)c1 +C=CC(=O)N1CC(C2CCNc3c(C(N)=O)c(-c4ccc(Oc5cccc(Cl)c5)cc4)nn32)C1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCC(C(=O)NCc3ccccc3)C2)c1 +CC(C)(C)C(=O)OCc1cc(C(C)(C)C)ccc1CN=C(S)NCc1ccc(NS(C)(=O)=O)c(F)c1 +O=C(O)C(Cc1ccc(-c2ccccc2)cc1)NC(=O)C1(S(=O)(=O)C2CCCCC2)CCCC1 +OCC1OC(n2cc(-c3cccnc3)nn2)C(O)C(O)C1O +CN1CCCC(Cc2ccccc2)(c2cccc(OCCNS(=O)(=O)c3cnn(C)c3)c2)C1 +CCCOc1ccc(C(N)=O)cc1-c1nc(O)c2cc3c(cc2n1)ncn3Cc1ccc(F)cc1 +O=C(C1CCOCC1)N1CCC(Oc2ncnc3c2CN(c2cnc4ccccc4c2)CC3)C1 +Cc1ccc(F)c(NC(=O)c2cccc(Oc3ccnc4cc(C(=O)O)sc34)c2)c1 +Cc1cc(CCCC(CC(=O)NO)C(=O)NC(C(=O)NC(C)c2ccccc2)C(C)(C)C)ccc1-c1ccccc1 +CN1c2ccc(OC(=O)Nc3ccc4c(c3)OCO4)cc2C2(C)CCN(CCc3ccccc3)C12 +CCc1ccc(-n2cnc3c(sc4nccc(NCC(F)(F)F)c43)c2=O)cc1 +CN(C)c1ccc(C2CC3(C)C(CCC3[N+](=O)[O-])C3CCC4CC(C)(O)CCC4C23)cc1 +O=C1C(=Cc2ccc(OCCCCO)cc2O)Oc2c1ccc(O)c2O +COc1ccc(-n2nc(C)cc2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cn2)cc1 +O=C(O)CCCCCCOc1ccc2cc1COCC=CCOCc1cccc(c1)-c1ccnc(n1)N2 +COc1cc(C(=O)NCc2cc(F)cc(F)c2)ccc1-c1cn[nH]c1 +CC(NC(=O)C1CC2CC2N1C(=O)Nc1cn(C(N)=O)c2ccccc12)C1CC1(Cl)Cl +O=C(O)Cc1cnc(C(=O)c2ccc(C(=O)Nc3ccc(Cl)cc3)cc2)c2ccccc12 +CCS(=O)(=O)Nc1cccc(Oc2cc(F)c(F)c(Nc3ccc(I)cc3F)c2C(N)=O)c1 +Cc1ccc2c(c1)CCC2NC(=O)COc1cc(C)c2c(C3CC3)nn(C)c2n1 +Cc1noc(C)c1-c1cc(C(O)(c2ncccn2)c2ccc(F)cc2F)c2nc(C3CC3)[nH]c2c1 +CC(=O)N1CCN(Cc2cn(S(=O)(=O)c3ccccc3Br)c3ccccc23)CC1 +CN(C(=O)NC1CCN(c2cccc(C#N)c2)CC1)C1CCN(S(C)(=O)=O)CC1 +COc1cc(CCN2CCN(CC(OC)c3ccc4c(c3C)COC4=O)CC2)ccc1C#N +O=C(NN1CCN(c2nc(-c3ccc4ccccc4n3)no2)CC1)C1CCC(F)(F)CC1 +NC1(C(=O)NC(CCCN2CCOCC2)c2ccc(Cl)cc2)CCN(c2ncnc3[nH]ccc23)CC1 +O=c1oc2ccccc2n1CCCCCN1CCN(c2ccccc2)CC1 +COc1ccc(C2c3nc(NC(C)C)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)c(CN(C)C(C)=O)c1 +O=C(CCCC1OOC(CCCC(=O)c2ccc(F)cc2)OO1)c1ccc(F)cc1 +O=C(NS(=O)(=O)c1ccc(Cl)cc1)c1ccc(Cl)cc1Br +O=C(CO)N1CCC(c2[nH]nc(-c3ccc(Cl)cc3)c2-c2ccncc2)CC1 +CC=CC(=O)Nc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OCCCN1CCOCC1 +COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)c(=O)n(C)c1)C2=O +CCCOCc1ccc(Cl)c(-c2nnc3c(C)nc4ccncc4n23)c1 +COc1cc(F)ccc1N1CCN(CCCNc2c(C(=O)N(C)C)c[nH]c3ccn[n+]2-3)CC1 +Cc1noc(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)c1Br +CC(=O)Nc1cc(-c2cc(S(N)(=O)=O)c(C)s2)no1 +CS(=O)(=O)CC1CCC(Nc2nccc(-n3ccc4c(N5CCN(C(=O)CC#N)CC5)cccc43)n2)CC1 +COc1ccccc1-n1nc(C2CCN(S(C)(=O)=O)CC2)cc1-c1ccc(Cl)s1 +O=C(Cc1ccc(-c2ccccc2)cc1)NC1CCOC1=O +COc1cccc2c1-c1cccc3c1C(C2)N(C(C)C)CC3 +OC(CNC12CC3CC(CC(C3)C1)C2)COc1cccc2[nH]ccc12 +CCN(CCCNC(=O)CCn1c(=O)[nH]c2ccsc2c1=O)c1ccccc1 +COC1Cc2c(csc2-c2ccc(-c3ccccc3)cc2)C2(CCN(Cc3ccccc3)CC2)O1 +O=C(NO)c1cnc(NC2(c3ccccc3)CCN(C(=O)Nc3ccc(F)cc3)CC2)nc1 +CN1CCN(Cc2ccc(NC(=O)Nc3cc(C#Cc4cnc5cnccn45)n(C)n3)cc2C(F)(F)F)CC1 +Cc1cc(Oc2nccc3n[nH]cc23)ccc1-n1c(C)nc2cnccc21 +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)NC3CCC(N)CC3)cc2F)cn1 +CNC(=O)C(C)(C(=O)NO)N(C)C(=O)c1ccc(C#Cc2ccc(CN3CC(OC)C3)cc2)cc1 +CCCCN(CCCC)CCCOc1ccc(-c2nc(-c3ccccc3)sc2CC)cc1 +O=c1ccc2cnc3ccc(-c4ccc5ccccc5c4)cc3c2n1-c1ccc(N2CCNCC2)c(C(F)(F)F)c1 +CCCCCN(CCCCC)C(=O)c1cc(-c2ccccc2)no1 +CSc1nc(NC(=O)C(c2ccccc2)c2ccccc2)n2nc(-c3ccco3)nc2n1 +COc1ccc(OCC(=O)Nc2ccc3nc(N4CCCC4)nc(C)c3c2)cc1 +CCCN1Cc2n[nH]c(=O)c3cc(F)cc4[nH]c(c2c43)C1 +COc1cc(-c2cn(C3CC(C4CCCCC4)CCNC3=O)nn2)ccc1-n1cnc(C)c1 +O=C(NN=Cc1ccc(Sc2nc3ccccc3[nH]2)o1)c1cccc([N+](=O)[O-])c1 +CC1=C(C#N)C(=O)N(C)C(=O)C1=Nc1ccc(N(C)C)cc1 +COc1cc(NS(=O)(=O)c2ccccc2)ccc1-c1cncc2ccccc12 +Cc1c(C(=O)NCC2CC3CC(C2)C3(C)C)ncn1-c1ccccc1 +O=C(CCCCCN1CCN(c2ccccc2O)CC1)NC1CCCc2ccccc21 +CCCCCCCCCCCCCCCC(=O)OCCSCC(NC(=O)C(F)(F)F)C(=O)NC(CO)C(=O)OC +N#CCCCCCc1cnc(C(=O)CCCCCCc2ccccc2)o1 +Cc1cc(NC(=O)N2CC3CC(c4ccccc4C(F)(F)F)CC3C2)c(C(=O)O)cn1 +COc1cc(Cl)c(Cl)cc1N1CCN(CCn2cnc3sc4c(c3c2=O)CCN(C)C4)CC1 +N#Cc1cc(Cl)cc(Oc2c(Br)ccn(Cc3n[nH]c4ncccc34)c2=O)c1 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+COc1cccc2c1CCN(Cc1ccc(C(C)NC(=O)C3CC3)cc1)C2 +CCCCc1c(C)c(OC)c2c(ccn2C)c1OC(C)=O +CCn1c(C)c(-c2cnc(C)nc2OCC2CC2c2ccc3ccccc3n2)ccc1=O +Cc1cc(NC2CCCC2)nc2ccc(NC(=O)COc3ccc(C(F)(F)F)cc3)cc12 +NCC(=O)NCCOc1cc(-c2ccccc2Cl)c2ccc(=O)n(-c3c(Cl)cccc3Cl)c2c1 +COc1ccc(C=C2CC(CO)(COC(=O)c3ccc([N+](=O)[O-])cc3)OC2=O)cc1 +C=C(C)C1CCC2(C(=O)OCc3ccccc3)CCC3(C)C(CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C12 +COC(=O)c1ccc(N2CCN(C)CC2)cc1NCCc1ccccc1 +CNC1Cc2ccc(OCCNS(=O)(=O)c3cn(C)cn3)cc2C1Cc1ccccc1 +O=S(=O)(NCC(c1cccnc1)N1CCN(Cc2ccccc2)CC1)c1ccccc1 +CCc1cc(CCc2ccccc2)nn1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2ccccc2)CC1 +CC(=O)N(CCc1nc2ccccc2c(=O)n1-c1ccc(Cl)cc1)C(C)=O +c1cncc(CCNc2nccn3c(-c4ccc5ccccc5c4)cnc23)c1 +O=C(OCC1CCCC(c2cc(F)ccc2F)N1S(=O)(=O)c1ccc(Cl)cc1)N1CCC(N2CCCCC2)CC1 +Cc1cnc2n1-c1cc(Cl)c(Cl)cc1N=C(c1ccc(-n3c(C)nc4cnccc43)cc1)C2 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(F)(Cc2ccccc2)C1 +CC(C)CS(=O)(=O)N1CCCC(NC(=O)Nc2cnc3[nH]ccc3n2)C1 +Cc1c(N2CCCCCC2)nc(C2CC2)nc1N1CCCCCC1 +COC1CCC(NC(=O)c2n[nH]cc2NC(=O)c2ccccc2C(F)(F)F)CC1 +COc1ccc(Sc2ccc3c(c2)N=C(c2ccc(C(=O)O)cc2)c2cc4c(cc2N3C)C(C)(C)CCC4(C)C)cc1 +Nc1ncnc2c1c(-c1ccc(Nc3nc4cccc(Cl)c4o3)cc1)nn2C1CCC(N2CCOCC2)CC1 +O=C(O)C(CCC(=O)N1CCC(CCCC2CCNCC2)CC1)NS(=O)(=O)c1ccc2ccccc2c1 +COCCNc1cc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)ncc1C(F)(F)F +O=C(Cn1nnc(-c2ccccc2)n1)NN=Cc1cc([N+](=O)[O-])ccc1O +CC(O)CNc1nc(NCc2ccc(-c3ccccn3)cc2)c2[nH]nc(C(C)C)c2n1 +CCCCCCOP(=O)(O)C1=CC(C(NC(C)=O)C(CC)CC)C(NC(=N)N)C1 +CC(C)OC(=O)C1C(=O)C(=Cc2c[nH]c3ncccc23)OC1=NN1CCOCC1 +Cc1ccnc2nc(-c3cccc4ccccc34)cc(O)c12 +COc1ccc2c(c1)CN(C(=O)NCc1ccc3c(c1)CCO3)CCS2 +COc1cccc(C2=C(c3c(C)n(C)c4ccccc34)C(=O)NC2=O)c1 +Cc1nn(Cc2ccccn2)c(C)c1CC(=O)NCc1ccc(F)cc1Cl +O=C(CCCN1C(=O)c2ccccc2S1(=O)=O)Nc1ccc(C(=O)NO)cc1 +O=C1NCN(c2ccccc2)C12CCN(C1CCCCC1c1ccc(Cl)c(Cl)c1)CC2 +O=C(NC1Cc2ccccc2C1)c1cc2sc(Cl)c(Cl)c2[nH]1 +CCNC(=O)N1CCC(N2CCN(C(C)c3ccc(S(=O)(=O)c4ccc5c(c4)OCO5)cc3)C(C)C2)CC1 +N#Cc1cncc(Cc2ccc3c(c2)-c2nc(N)nc(-c4ccccc4)c2C3=O)c1 +[N-]=[N+]=Nc1ccc(S(=O)(=O)Nc2ccnn2-c2ccccc2)cc1 +O=C(Nc1cccc2ccc(O)cc12)NC1CCc2cc(F)ccc2C1Cc1ccc(C(F)(F)F)cc1 +CCCN(CCCc1ccc(F)cc1)CC(O)C(C)NC(=O)Nc1cccc(-c2nnnn2C)c1 +CC(C)CCCC(C)C1CCC2C3=CCn4c(=O)ccc(=O)n4C3CCC21C +Cc1cc(-c2ccc3c(c2)CCN(CCCSc2nnc(C(C)C)n2C)CC3)no1 +Nc1cnc(-c2ccc(C3CCC3)c(Oc3ccnc(N)n3)c2F)cn1 +O=C1NC(=O)C(CC(=O)N2CCN(c3cccc(CNC(=O)c4nc5ccccc5c(=O)[nH]4)c3)CC2)N1 +O=C(NCC(F)(F)F)Nc1cccc(-c2cnc3cc(-c4cnn(C5CNC5)c4)ccn23)c1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1ccccc1OC(F)F +CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CC1CCCN1C +CCOC(=O)C1=C(C)NC2=C(C(=O)C(C(=O)OCC)C(c3ccccc3OC)C2)C1c1ccc(OC)c(OC)c1 +CC(C)(C)c1cc(C=Cc2ccc(F)cc2)cc(C(C)(C)C)c1O +CC(C)(C)OC(=O)NCCOc1cccc2c1cnn2-c1ccccc1F +CCCNc1nc(N(C)C)nc2c1cnn2CC(Cl)c1ccccc1 +CC(C)(C)NCc1ccc2c(c1)OCCC2NC(=O)CC(NS(=O)(=O)c1ccc(F)c(Cl)c1)c1ccccc1 +CC(C)C1SC(Nc2ccccc2C(F)(F)F)=NC1=O +O=C(NCCCCN1CCC2c3ccc(O)cc3CCC21)c1ccc(-c2ccccc2)cc1 +CCCCCCCCn1cc2c(nc(NC(=O)NCCCCC)n3nc(-c4ccco4)nc23)n1 +Oc1ccc2c3c1OC1c4c(c5ccccc5n4CCF)CC4(O)C(C2)N(CC2CC2)CCC314 +CC(C)n1cnc2c(NCc3ccc(-c4ccc(Cl)s4)cc3)nc(NC3CCC(N)CC3)nc21 +COc1cc(C(=O)NC(C)c2ccccc2F)ccc1-c1cn[nH]c1 +O=Cc1nc2c(cc1CO)CCCN2C(=O)Nc1ccc(C(F)(F)F)cn1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)Nc1cnc2ccccc2c1 +COC1C(OC(=O)NC(C(=O)NCCC2CCCN2C)C(C)C)CCC2(CO2)C1C1(C)OC1CC=C(C)C +O=C(NCc1ccc(S(=O)(=O)c2ccc(N3CCOCC3)nc2)cn1)c1cc2ccncc2s1 +NC(=O)c1cc(-c2ccnc(NC3CCCCC3)c2)nc(N2CCNCC2)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2C=NOCCn1c(=O)cc[nH]c1=O +O=C(Nc1ccc(Br)cc1)NC1CCC(Oc2ccc(F)cc2)CC1 +N#CCCNS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1 +CCCOc1ccc(C(=O)NO)cc1NC(=O)c1ccccc1 +O=C(NC1CCC(O)CC1)NC12CC3CC(CC(C3)C1)C2 +Cc1cc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3ccccc3OC(F)F)cc2)cs1 +COc1cc(Nc2nccc(Nc3cc(C)[nH]n3)n2)ccc1-c1nc2ccccc2s1 +O=C(CCC(F)(F)F)N1CCC(c2nc(-c3ccccc3)no2)CC1 +Cn1cc(-c2ccc(N3CCC(N4CCc5ccccc54)CC3)nn2)cn1 +O=C(NO)c1ccc(N2CCN(CCCN3CCOCC3)C2=O)cc1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3cncc(Cl)c3)c2)c2cncnc21 +Cn1cnc(-c2cc3nccc(Oc4ccc(NC(CC(=O)Nc5ccc(F)cc5)C(F)(F)F)cc4F)c3s2)c1 +CCN1C(=O)c2nc(-c3ccc(C#N)c(F)c3)n(Cc3ccc(F)c(F)c3)c2N2CC(C(C)C)N=C12 +Clc1ccc(Nc2nc(N3CCNCC3)nc3ccccc23)cc1 +Cc1cccc(C)c1Nc1ccc(C(=O)NCCCCCCC(=O)NO)cc1F +CC1(CC(=O)NCc2ccc([N+](=O)[O-])cc2)CC2(CCCCC2)OO1 +Cc1ccc(N2CCc3ncnc(NC(CO)c4cnc(C)nc4)c3C2)c(C#N)c1 +Nc1ncc(-c2cnn(C3CCNCC3)c2)cc1-c1nc2ccccc2o1 +O=C(NCc1cncc2ccccc12)N1C(=O)OC(c2cccc(C(F)(F)F)c2)C1CO +O=C(O)Cc1sc(C2COc3ccccc3O2)nc1-c1ccc(Cl)cc1 +COCCCn1c(NC(=O)c2cccc(C#N)c2)nc2cc(C(=O)N3CCCCC3)ccc21 +O=C(N1CCN(c2ccccc2[N+](=O)[O-])CC1)n1nnc2ccccc21 +COc1ccc(-c2cnc(C3CCC3)o2)cc1S(N)(=O)=O +CN(C)CCn1c(=O)c2ccc(NCCNCCO)c3c(=O)c4cc(O)ccc4n(c1=O)c23 +COCCCOc1ncccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 +O=[N+]([O-])c1cc2c(OCCC3CCCCN3)c(-c3ccsc3)c(O)nc2cc1Cl +CC(C)=CCCC(C)=CCCC(=CCOP(=O)(O)OP(=O)(O)O)CC(C)C +ON=C(CCN1CCN(c2ccccn2)CC1)c1ccccc1Cl +Cn1cc(C2=C(c3cn(C4CCN(Cc5ccccn5)CC4)c4ccccc34)C(=O)NC2=O)c2ccccc21 +O=C1c2ccc(S(=O)(=O)O)cc2C(=O)c2ccc(S(=O)(=O)O)cc21 +COC1CCN(c2ncc(F)c(N3CCC(Oc4ccc(C(C)NC(C)=O)cc4)C3)n2)CC1 +Cn1c(-c2ccc(-c3ccncc3)cc2Cl)nnc1C1(c2ccc(Cl)cc2)CCC1 +CCc1cccc(NC(=O)Nc2csc(-c3cc4ccccc4n3C(N)=O)c2)c1 +CCC(CC)Nc1cc(C)nc2c(-c3ccc(OC)cc3C)c(C)nn12 +N#Cc1cc(F)cc(C(=O)N2CCn3nc(COc4ccccc4)cc3C2)c1 +CCNC(=O)Cn1c(=O)n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c2ccccc21 +OCc1ccc(-c2nnc(SCCCN3CCN(c4nsc5ccccc45)CC3)o2)cc1 +CC(C)CC(NC(=O)CC(NC(=O)C1CCCCC1)c1cccc(F)c1)B(O)O +O=C(NC1CCCOC1)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CCOc1cccc(-c2cc(COc3ccc(CCC#N)cc3)cc3cccnc23)c1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccc(N4CCOCC4)cc3)n1)CCN(CC(=O)N(C)C)CC2 +CC#CC1(O)CCC2C3CCC4=CC(=O)CCC4=C3C(c3ccc(N(C)C(=O)NCCCC)cc3)CC21C +Fc1cccc(-c2cc(-c3cnn(C4CCNCC4)c3)on2)c1Cl +CCCC(C)COc1ccc(C(CO)NC(=O)Cc2ccccc2)cc1 +CC1CCCN1CCCOc1ccc(-c2ccc(=O)n(C)n2)cc1F +O=C(Nc1ccc(-c2cccc3sncc23)cc1)Nc1ccc(F)c(C(F)(F)F)c1 +CN1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cn5ccc(C#N)cc5n4)c3)sc2C1 +Cc1nc(S(C)(=O)=O)ccc1Nc1ncnc(OC2CCN(C(=O)OC(C)C)CC2)c1C1CC1 +Nc1ncc(-c2nc(N3CCOCC3)nc3c(CN4CCN(C(=O)CO)CC4)csc23)cn1 +CC(C)Oc1cncc(C2=CC3CC(C2)CN(C)C3)c1 +CN(C)CCNc1c2c(c(C#N)c3nc4ccccc4n13)CCCC2 +Cc1csc2c(N3CCNCC3)nc(-c3ccncc3)nc12 +CCCCCCC(C(=O)N1CC(Oc2ccccc2)CC1C(=O)O)n1cnc(NC(=O)c2ccccc2S(=O)(=O)O)c1 +N=C(N)c1ccc(CCC(CC(=O)n2cccc2)c2cccc(C(=N)N)c2)cc1 +COC1CCC(CC(=O)NC2CCC(CCN3CCN(c4nccc5occc45)CC3)CC2)C1 +COc1ccc(C(=O)NC(=S)Nc2sc3c(c2C(=O)O)CC(C)(C)OC3)cc1 +CCCCc1c(Oc2ccc(-c3ccccc3-c3nn[nH]n3)cc2)nc2c(C(=O)O)c(N)ccc2[n+]1[O-] +CCCC(CC1CCc2c(cccc2OCC(=O)O)C1)=NOC(c1ccccc1)c1cccnc1 +CC(C)(C(=O)O)c1cccc(OCCCN(Cc2cccc(C(F)(F)F)c2Cl)CC(c2ccccc2)c2ccccc2)c1 +O=C(COc1ccc(-c2cccnc2)cc1)Nc1ccc(CN2CCNCC2)c(C(F)(F)F)c1 +COc1cccc(C(=O)Nc2cc(-n3ccn4nc(-c5cccnc5)cc34)c(C)cc2C)c1 +CC(NC(=O)N(C)C)c1ccc(OC2CCN(c3ccnc(OCC4CC4(F)F)c3F)C2)cc1 +CC(=O)N1CCC(COc2ccc3oc(-c4cc5sccc5cn4)cc(=NO)c3c2)CC1 +Clc1ccc(-c2c[nH]c(-c3nccc4ccccc34)n2)cc1Cl +CCCCNc1ccc2oc(-c3cc(-c4cnn(C5CCNCC5)c4)cnc3N)nc2c1 +O=C(NC1CCOCC1C(=O)NO)c1ccc(Cn2c(C(F)(F)F)nc3ccccc32)nc1 +CCCCCN(CCCCC)C(=O)N1CCN(C(=O)N(c2ccccc2)c2ccc(O)cc2)C(C(=O)O)C1 +Clc1ccccc1-c1ccccc1C=NNc1c(Cl)cncc1Cl +OCC1OC(n2cc(F)c3c(-c4ccsc4)ncnc32)C(O)C1O +CCCS(=O)(=O)N1CCN(C2(CNC(=O)c3c(F)cccc3F)CCCCC2)CC1 +CCOc1ccc2c(c1)n1ncc(Cl)c1n[n+]2[O-] +CCNC(=O)OCC1OC(n2cnc3c(NC4CCOC4)ncnc32)C(O)C1O +Cc1cc(Br)cc(C)c1Oc1nc(N)nc(Nc2ccc(C#N)cc2)n1 +CC(C)=CCC12OC(C)(C)C3CC(C=C4C(=O)c5ccccc5OC431)C2=O +O=C(CCCCCCc1ccccc1)c1nc(C(=O)C(F)(F)F)co1 +CC1CCc2nc(CCCN3CC=C(c4ccccc4)CC3)[nH]c(=O)c2C1 +CC(C)NC(=O)OC1(C(=O)CO)C(C)CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC21C +Cn1cc(-c2ccc3nc(NC(=O)c4cncc(-c5ccc(C#N)cc5)c4)cn3n2)c(-c2ccc(F)cc2)n1 +CCOc1cc2ncnc(Nc3ccc4c(cnn4Cc4ccccc4)c3)c2cc1NC(=O)C=CCN(C(C)C)C(C)C +O=C(Cc1ccc(Cl)c(Cl)c1)N1CCc2sccc2C1CN1CCCC1 +Cc1nc(-c2ccc(N3C(=O)c4n[nH]c(C(C)(C)C)c4C3c3ccccc3OCCO)cc2)no1 +O=C1c2ccc(C(F)(F)F)cc2OCN1CCO[N+](=O)[O-] +CCCCCNC(=O)NS(=O)(=O)c1cc([N+](=O)[O-])ccc1Oc1ccc(C)cc1 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+Nc1nnc(-c2ccc3[nH]cc(-c4cncc(N5CCCC5)n4)c3c2)s1 +CC(NC(=O)CNC(=O)Nc1ccc(C(=N)N)cc1)c1ccc(Br)cc1 +COc1ccc(-c2nnc(NC(=O)c3ccc(C4CCC(CC(=O)O)CC4)cc3)s2)cc1 +O=C(O)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1 +CCN(CC)CCCNC(=O)c1ccc(Nc2ncc(C)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +OCC1OC(n2cnc3c(NC4CC4)ncnc32)C(O)C1O +COc1ccc(N(Nc2ccc(Br)cc2)c2ccccc2N(Nc2ccc(Br)cc2)c2ccccc2OC)cc1 +Cc1ccc2c(c1)NC(c1ccccc1[N+](=O)[O-])C1=C(CC(C)(C)CC1=O)N2 +Fc1ccc(-c2ccc3c(c2)CCC=C3c2ccncc2)cc1 +FC(F)(F)Cn1nccc1-c1ccccc1NCC1=NCCN1 +CCOc1ccc(Cc2cc(C3SC(CO)C(O)C(O)C3O)ccc2O)cc1 +Cc1nc(-n2cnn(CCCC(F)(F)F)c2=O)sc1C(=O)NCc1cccnc1 +O=C(O)CC1OCCn2c1cc1cc(OCc3ccc(OC(CF)CF)c(Cl)c3)ccc12 +COc1cccc(-c2ccc(CCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(N)=O)cc2)c1 +CCC(CC)Nc1nc(C)nc2c(-c3cnc(N(C)C)cc3C)c(C)nn12 +CCC(=O)N1CCC(CN2CCC(NC(=O)c3cc(Cl)c(N)cc3OC)C(OC)C2)CC1 +O=C(c1ccccn1)N1CC2CC34CCC1C2C31CCN(CC2CC2)C4Cc2ccc(O)cc21 +O=C(Nc1nc2ccccc2[nH]1)C12CC3CC(CC(C3)C1)C2 +Nc1cc(C(F)(F)F)nc(SCc2ccc3ccccc3c2)n1 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+CCCCCc1ccc(C(=O)N(CCCC(C)Nc2cc(OC)cc3cccnc23)Cc2ccc(OC)c(OC)c2)cc1 +CN(Cc1n[nH]c(O)n1)CC1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +CCCc1ccc(-c2onc3c2COc2cc(CN4CC(C(=O)O)C4)ccc2-3)cc1 +Cc1cc(Nc2cc(OC3CCCCC3)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1 +N#Cc1ccc(OCc2ccsc2)cc1OC(C(=O)O)c1ccsc1 +COc1ccc(-c2ccc3nc(N)n(-c4ccccc4)c(=O)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +COc1ccc(Br)cc1S(=O)(=O)Nc1onc(C)c1C +COc1cc(C)nc2c(-c3ccc(Cl)cc3Cl)cccc12 +N#Cc1ccc(N2CC3C(C2)C3NCC(=O)N2CC(F)CC2C#N)cc1Cl +COc1cc(OC)cc(N(CCN)c2ccc3ncc(-c4cnn(CC5CCOCC5)c4)nc3c2)c1 +COc1cc(OC)cc(N(CC2COCC(C)(C)N2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CCS(=O)(=O)N1CC(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +O=C(NCCO)c1ccccc1Oc1ncc(Cl)cc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +O=C(NO)c1cc2c(cc1F)CCC(NS(=O)(=O)c1cccc(Cl)c1)C2 +O=C(Nc1nnc(SCc2ccccc2)s1)c1ccccc1Cl +Cc1[nH]c(C)c(-c2ccc(OCc3ccc(OC(F)(F)F)cc3)nc2)c(=O)c1Cl +COc1ccc(S(=O)(=O)N(CCC2CCCCC2)CC(=O)NO)cc1 +Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(Cl)cc1 +O=C(NCC1C2CC3CC(C2)CC1C3)C1C2c3ccccc3C(c3ccccc32)C1C(=O)N1CCCC1C(=O)O +C=C1CCN(c2ncc(C#Cc3ccc(CC(C)NC(C)=O)cc3)cn2)CC1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)n2nc(N(C)Cc3ccccc3)nc12 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC4CCOC4)ncc23)ccn1 +O=C1C(=O)N(Cc2ccncc2)c2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc21 +COc1c(C(=O)OCC(C)CC2=C(O)C(=O)c3ccccc3C2=O)ccc2ccccc12 +COc1ccccc1NC(=O)N1CC(C(=O)N2CCCC2)C=C2c3cccc4[nH]cc(c34)CC21 +CC(NC(=O)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1)C1CCCCC1 +CCN(C(=O)CO)C1CN(C(=NC#N)Nc2ccc3c(c2)OC(F)(F)O3)N=C1c1ccc(Cl)cc1 +CCOC(=O)C=Cc1cnc(Nc2ccc(OC(C)C)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O +CCOc1ccc(CC(NC(=O)c2cnc(Cl)c(Cl)c2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)cc2)cc1 +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CC2OC(=O)C(=C)C2CC(C)C)CC(O)CC1O +O=C(c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1)N1CCN(C2CCCC2)CC1 +CNS(=O)(=O)c1ccccc1-c1ccc(NC(=O)C2(Cn3cnnn3)CC(c3cccc(C(=N)N)c3)=NO2)cc1 +Cc1nn(C)cc1C(=O)N1CCC2(CC1)CC2CNC(=O)N1Cc2ccncc2C1 +O=C(NC1CCN(Cc2ccn(-c3ccc(C(F)(F)F)cc3)c2)CC1)N1CCCC1Cc1cccnc1 +O=C1N(c2ccc(F)cn2)CCc2nc(COc3ccccc3)cn21 +Cc1ccc(C(=O)Nc2ccc(CN3CCN(C)CC3)cc2)cc1C#Cc1nn(C(C)C)c2ncnc(N)c12 +CNc1nc2ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc3ccccc3)NC(=O)OC3COC4OCCC34)cc2o1 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(C)c2C)c1 +CC(=O)c1ccc(S(=O)(=O)Nc2cccc(-n3cnnn3)c2)cc1 +COc1cnc(-n2cnc(C)n2)c2[nH]cc(C(=O)C(=O)N3CCc4c(-c5ccccn5)cccc4C3O)c12 +CC(C)=CCC1C(=O)C(C(=O)CC(C)C)=C(O)C(O)(CC=C(C)C)C1=O +Nc1nc2c(c(=O)n(CC3CC3)c(=O)n2CC2CC2)n1S(=O)(=O)c1ccc([N+](=O)[O-])cc1 +Cc1cc(N2CCOCC2)cc2[nH]c(-c3c(NCCc4nc(C)n(C)c4Cl)cc[nH]c3=O)nc12 +COc1cc(C=Cc2ccc3ccccc3c2)cc([N+](=O)[O-])c1OC +C=CC(=O)NCCc1c(Cc2ccccc2)oc2ccc(OC)cc12 +NCc1ccc(CC(CP(=O)(O)C(N)CCc2ccccc2)C(=O)O)cc1 +Fc1ccc(-c2cnc3cc(-c4ccco4)ccn23)cc1 +Cn1c(=O)c2nc(-c3ccc4ccccc4c3)[nH]c2n(C)c1=O +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)c2ccc3c(cnn3CCCNC3=NCCN3)c2)C(=O)O)c(C)c1 +COc1nccc2c3cnc(Nc4ccc(N5CCC(N6CCCC6)CC5)cn4)nc3n(C3CCC(C)(C)CC3)c12 +O=C1NCc2ccc(OCCCN3CCN(c4cccc5cc(F)ccc45)CC3)c(F)c21 +CC(O)CNC(=O)c1c[nH]c(-c2n[nH]cc2CN2CCN(c3ccc(C(F)(F)F)cn3)C(C)C2)c1 +CC1(C)CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 +CCCCCN1CC(C)C(C)(c2cccc(O)c2)CC1CCC +Nc1nc(-n2cc(CO)nn2)nc2c1ncn2C1OC(COS(=O)(=O)NC(=O)c2ccccc2O)C(O)C1O +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3ccc(Cl)cc3)o2)c1 +O=C(CN1C(=O)c2ccccc2S1(=O)=O)c1ccccc1Cl +O=C(Nc1nccc2nn(-c3c(Cl)cccc3Cl)cc12)C1CC1 +NS(=O)(=O)c1cn(CC(=O)NS(=O)(=O)c2ccc(Cl)cc2)ccc1=O +CN(C)CC(=O)NCCc1c[nH]c2ccc3c(c12)CCNC3=O +CCCCCCCCCCCCSC(=O)CS(=O)(=O)Nc1c(C(C)C)cccc1C(C)C +Cc1cccc(COc2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)c1 +O=C(NCc1cccc(-c2cccc(-c3cc4c[nH]ccc-4n3)c2O)c1)C(CO)c1ccccc1 +CN(C)C1CC2CCC(C1)N2c1ccc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)nc1 +CC1CC(N(C)C(C)C)CCC1N1CCC(Nc2ncnc3ccc(C(F)(F)F)cc23)C1=O +CCNC(=O)c1noc(-c2cc(CCc3ccc(F)cc3)c(O)cc2O)c1-c1ccc(CN2CCCCC2)cc1 +O=C(Nc1ccc2sc(CO)nc2c1)c1ccc(Cl)cc1 +CCc1[nH]c2cc(F)ccc2c1C1CCN(CCCSc2ccc(O)cc2)CC1 +COc1ccc2[nH]cc(C(=O)OCC34CCN(CC3)CC4)c2c1OC +Cc1ccc(N2CCc3ncnc(NC(C)c4ccc(Br)cc4)c3C2)nc1 +NC(=O)C(Cc1ccccc1)NC(=O)C(CS)NC(=O)COc1ccccc1 +Brc1c(Br)c(Br)c2[nH]c(NCC3CCNCC3)nc2c1Br +NC(=O)N1CCC(Oc2cccc3ccc(-c4nnc5ccccn45)nc23)CC1 +COC(=O)N(NC(=O)c1c(CN2CCN(C(C)C)CC2)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +COc1cc(Oc2c(C)cc(C#N)cc2C)cc(Nc2ccc(C#N)cc2)n1 +CCc1nc2ccc(OC3CCN(C(C)=N)CC3)cc2n1CC=Cc1ccc(N)cc1 +O=C(NCCO)c1ccc(S(=O)(=O)N(Cc2ccccc2)c2ncc(C(F)(F)F)cc2Cl)cc1 +CC(CCc1ccc(OC(=O)c2ccccc2)cc1)=NNC(N)=S +Cc1cc(I)ccc1Nc1c(C(=O)O)cc(F)c(F)c1F +CCCCCCCCCCCC(=O)OC1C(OC2(CO)OC(CO)C(O)C2OCC(C)C)OC(CO)C(O)C1OCC(C)C +COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3ccccc3s2)n1 +O=C(CC(NC(=O)c1ccccc1)c1cccc(Cl)c1)NC(Cc1ccc(F)cc1)B(O)O +C=CC1CN2CCC1CC2C(OCCc1cn(-c2ccc(OC)cc2)nn1)c1ccnc2ccc(OC)cc12 +COc1ccc(N2CCN(CCn3cnc4c3nc(N)n3nc(-c5ccco5)nc43)CC2)cc1 +CCOc1c(I)cc(CO)cc1CNCCCNc1cc(O)c2ccccc2n1 +CC(C)(C)OC(=O)Nc1ccc(Cn2cc(NC(=O)CCCCCCC(=O)NO)cn2)cc1 +Cn1cc2c(nc(NC(c3ccccc3)c3ccccc3)n3nc(-c4ccco4)nc23)n1 +COc1ccc2c(c1)OCCCCCOCCN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC3OCCC13)S2(=O)=O +C=C1C(=O)C23CCC4C(C)(C)C(OC(C)=O)CC(O)C4(C)C2C(OC(C)=O)CC1C3 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1cc(Cl)cc(Cl)c1 +O=S(=O)(Nc1nccs1)c1ccc2c(c1)OCCC2c1ccc(C(F)(F)F)cc1Cl +Cc1cc(C)c(C(=O)NC(Cc2ccc(N3CCC(c4ccc5c(n4)NCCC5)CC3)cc2)C(=O)O)c(C)c1 +Cc1nc2cc(-n3ncc(C(=O)c4cc5c(C)cccc5[nH]4)c3N)ccc2[nH]1 +C[N+]1(CC2CCCCC2)CCc2c(sc(NC(=O)Nc3ccc(Cl)cc3)c2C(N)=O)C1 +C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C4CC4)ncn3)CC2)c2cc[nH]c2c1=O +O=C(NO)c1ccc2c(c1)CCN(S(=O)(=O)c1ccc(C(F)(F)F)cc1)C2 +O=S(=O)(c1ccc(Cl)nc1)N(Cc1ccc(F)c(C(F)(F)F)c1)c1sc2ccccc2c1Br +Cc1csc(-c2nc(C)[nH]c2-c2ccc3ncsc3c2)n1 +NS(=O)(=O)c1cc2c(s1)[S+]([O-])CC(=O)N2 +Cc1ccc2cc(C(=O)NC3(C(=O)NC(CCCC4CCN(CC5CCOCC5)CC4)Cc4ccccc4)CCCC3)sc2c1 +Cc1c(-c2noc(-c3ccc(OC(C)C)c(C#N)c3)n2)ccc2c1CCN(C(CO)CO)C2 +O=C1CC(c2c[nH]c3ccccc23)C(=O)N1CCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +COc1ccc(C(=O)N2CCCC(Nc3cnc(C(F)(F)F)cn3)C2C)c(-n2nccn2)c1 +Cn1cc(F)cc(C2CCCN2c2ccn3ncc(C(=O)NC4CC4)c3n2)c1=O +CC(=O)OC1CC(C(=O)O)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +COc1ccc2[nH]c(C(=O)NCCCN3CCN(c4ccccc4OC)CC3)cc2c1 +CCCN1CCC(N2CC(NCc3ccc4c(c3)c3ccccc3n4CC)CC2C(=O)NCC)CC1 +CC(C)(O)c1ccccc1-c1ccc2[nH]c(C#Cc3ccc(C(F)(F)F)cc3)nc2c1 +O=C(NC1CCCC1Nc1ccc(C(F)(F)F)cn1)c1cc(Cl)ccc1-n1nccn1 +CCCCC(NC(=O)OC(C(C)C)C(C)C)C(=O)C(=O)Nc1ccccn1 +O=C1Cc2c(OCCN3Cc4ccccc4C3)ccc(F)c2N1 +CCOc1cc(CN2CCC(Nc3nc4cc(Cl)ccc4o3)CC2)ccc1OC +CNC(=O)c1cc(-c2ncnc(C)c2C#Cc2ccc(N)nc2)ccc1F +CCN1C(=O)c2c(nc(OC)n2Cc2ccc(O)c(C#N)c2)N2CC(Cc3ccccc3)N=C12 +Nc1ncnc(N2CCN(Cc3cc(Cl)c(Cl)cc3OC3CNC3)CC2)c1-c1ccc(F)cc1 +CC(=O)C1(O)CCC2(C)C1C(O)CC1C3(C)CCC(O)C(C)(C)C3CCC12C +NC1CCC(Nc2cc(-c3cccc(NCc4ccc(OC(F)F)cc4)n3)c(Cl)cn2)CC1 +CC(C)(C(=O)Nc1nncs1)C(c1ccccc1)c1ccc2c(cnn2Cc2ccccc2)c1 +O=C1NC(=O)C(c2ccc(-c3ccc4ccccc4c3)[nH]c2=O)(C(F)(F)F)O1 +Cc1ccc(-n2c(C)nc3c(Nc4ccc(-c5ccncc5)cc4)ncnc32)c(C)c1 +CCC(NC(=O)c1ccc2c(ccn2C(=O)c2cccc(F)c2F)c1)c1ccccc1 +CCCN(c1ccccn1)C1CCN(CC2CN(C(=O)N3CCCC3)CC2c2ccccc2)CC1 +COc1ccc2c(c1)CN(C(=S)Nc1ccccc1)CCS2 +NC1(c2ccc(-c3nc4ccc(-c5cnc[nH]5)cn4c3-c3ccccc3)cc2)CCC1 +COc1cc(CN(C)C(C)c2ccc3c(c2)CCO3)ccc1OCCN1C(=O)CN(C)C1=O +O=S(=O)(Nc1ccncn1)c1ccc2c(c1)OCCN2c1ccc(C(F)(F)F)cc1Cl +COC(=O)C(C)(C)Cn1c(=O)[nH]c(=Nc2ccc(OC(C)C)c(Cl)c2)n(CC2CCCCC2)c1=O +CC(C)C(=O)N1CCCC12CCN(c1ncnc3[nH]ccc13)C2 +CCN(Cc1cnc[nH]1)c1ccc(CCc2ccc(Cl)cc2)cc1 +O=C(Cn1nc2ccc(Cl)cc2n1)NCC1CCCN2CCCCC12 +N#CC1(n2cc(C(NC(=O)c3ccsc3)C3CCCC3)nn2)CC1 +Cc1ccccc1-c1noc(Cn2nc(CC(=O)O)c3ccccc3c2=O)n1 +O=S1(=O)NC2(CN1CC(F)(F)F)C1CCC2Cc2cc(-c3cn(-c4ccc(Cl)cc4)cn3)ccc2C1 +Cc1cc(Oc2ncccc2OC(F)(F)F)ccc1-c1c(C)n[nH]c(=O)c1C +CC1C=C(c2c[nH]c(-c3ccc(F)cc3)c2-c2ccncc2)CCN1 +O=c1[nH]c2ccc(Nc3nccc(Nc4ccccc4Cl)n3)cc2[nH]1 +C[n+]1c2ccccc2c(N)c2cc(Nc3nc(N)nc(Nc4ccc5c(c4)c(N)c4ccccc4[n+]5C)n3)ccc21 +CCCc1nc2c(C)ccnc2n1Cc1ccc(OC(C(=O)O)c2ccccc2C)cc1 +Brc1cccc(Nc2ncnc3cc4[nH]ccc4cc23)c1 +FC(F)(F)c1ccc(Nc2noc3c(-c4ccc5[nH]ccc5c4)cccc23)cc1 +CCn1cc(C2(c3nnc(S)o3)NC(c3nc(-c4ccc(F)cn4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 +O=C1c2ccccc2C(=O)N1CCOCCN1CCN(c2nsc3ccccc23)CC1 +CCOCCOCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +c1ccc(CCCCN2CCN(Cc3cc4ccccc4o3)CC2)cc1 +COc1cc2c(cc1O)C1Cc3sc(CC(C)(C)C)cc3CN1CC2 +COc1ccccc1Oc1ccc(C(=O)N(Cc2ccc(C(=O)O)cc2)CC(F)F)cc1 +COc1ccc(S(=O)(=O)N2CCN(C(=O)Cn3c(=O)oc4ccc(Cl)cc43)C(CN3CCCC3)C2)cc1OC +COc1ccc2ccc(S(=O)(=O)NC3CCN(Cc4cc5c(N)nccc5s4)C3=O)cc2c1 +O=C(Nc1cccc(CCCCOCCCCCCNCC(O)c2ccc(O)c(CO)c2)c1)NC1CCCCC1 +CC(=O)c1ccc(OCCCN2CCC(NC(=O)C(C)NC(=O)OC(C)(C)C)C2)cc1 +Cn1cnc2cc(-c3ccc(C4(N)CC4)cc3)nc(NCCCO)c2c1=O +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC1(C(=O)O)CC1 +CCn1c(=O)n(CC)c2cc(-c3[nH]cnc3-c3ccccc3)ccc21 +CC(NC(=O)C(CCC(=O)O)NC(=O)Nc1ccc(C(=N)N)cc1)c1cccc(Br)c1 +CC(C)(C)NCc1ccc2c(c1)CCCC2NC(=O)CC1CCCCN1S(=O)(=O)c1cccc(Cl)c1 +CC1c2c[nH]nc2-c2cc(F)ccc2N1S(=O)(=O)c1cnn(C)c1 +O=C(Nc1nnc(-c2ccc3c(c2)CCCC3)o1)c1ccc(Cl)cc1Cl +CC(C)(C)NC(=O)c1ccccc1CC(O)C(CSc1ccc2ccccc2c1)NC(=O)c1cccc2c1CCNC2 +CN(Cc1ccccc1)CC1CCCC1c1c[nH]c2ccc(C#N)cc12 +O=C(NCc1cn[nH]n1)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=C1NCc2cc(Nc3ccc(F)cc3F)ccc2N1c1c(Cl)cccc1Cl +COC1CCC2(CC1)Cc1ccc(C#CC3CC3)cc1C21CC(=O)N(C)C(N)=N1 +O=S(=O)(NC1CCN(CCCO)CC1)c1cc(S(=O)(=O)c2ccccc2)ccc1C(F)(F)F +Cc1cc(C(=O)Nc2ccc(C3CCCNC3)cc2)ccc1Cl +CC(=O)c1sc(NC(=O)CCS(=O)(=O)c2ccccc2)nc1C +CC(C(=O)NCc1ccc(C2CC2)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 +COc1nc(Nc2cccc3c2nc(-c2ccc(F)cc2)n3C)ccc1-n1cnc(C)c1 +CCC1NC(=O)c2[nH]c3ccc(F)cc3c2-c2ccccc21 +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccccc3Cl)cc12 +COc1ccc2c(c1)C(NC(=O)CCCCN1CCN(c3ccccc3OC)CC1)CCC2 +NC(=O)c1c(-c2ccc(Oc3ccccc3)cc2)nn2c1Nc1ccc(OCc3ccncc3)cc1CC2 +CC1Cn2c(nnc2-c2cnccn2)C(=O)N1Cc1c(Cl)cccc1Cl +OCC1OC(c2cccc(CCc3ccccc3)c2)C(O)C(O)C1O +Cc1c(C(=O)O)sc2ncnc(Nc3ccc(F)cc3OC(C)CF)c12 +CC(C)(O)c1ccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)cc1 +COc1cc(Nc2cnc(C#N)c(OC(C)CN(C)C)n2)ncc1-c1cnn(C)c1 +OCC(O)CNc1cc(-c2ccc(Cl)cc2)nc2ccccc12 +COCCN(C)c1ncc2ncnc(Nc3cc(C(=O)Nc4ccc(OC)c(C(F)(F)F)c4)ccc3Cl)c2n1 +O=C(NO)C1CN(Cc2ccc(-c3ccc(F)cc3)cc2)C(=O)N1 +Cc1cccc(CCCCCCC(=O)c2ncc(-c3ccccn3)o2)c1 +Cc1cn2cc(CC(C)CN3CC4CCCCC4C(C(=O)N4CCN(c5ccc(F)c(F)c5)CC4)C3)ccc2n1 +CNC(C)C(=O)Nc1ccc2c(n1)CN(c1cccc(Cl)c1)C(=O)N2c1cccc(Cl)c1 +CCCCCC(=O)NCc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F +CC(=O)N1CCC(c2cc(Nc3cc(C(F)(F)F)ccn3)nc(N3CCC(F)(F)C3)n2)CC1 +CC1(C)CC(=O)c2sc(N3CCOc4ccc(-c5ccncc5)cc43)nc2C1 +Cc1cc(C)cc(C(=O)c2cc(Cl)ccc2Oc2ccnc(Nc3ccc(C#N)cc3)n2)c1 +O=C(Nc1cc(Cl)ccc1OC1CCC(O)CC1)c1cnn2cc(O)cnc12 +O=C1C(=Cc2ccc(F)cc2)CCC1=Cc1ccc(F)cc1 +CCN(Cc1ccn(C)n1)C(=O)CN(c1cc(N(C)C)ccc1Cl)S(=O)(=O)c1ccc(OC)c(OC)c1 +COc1ccc2c(=O)c(Cn3ccnc3)c(-c3ccc([N+](=O)[O-])cc3)oc2c1 +COc1ccc(CNc2nc(N3CC4CC4C3)ncc2C(=O)NCc2ccccn2)cc1Cl +O=C(Nc1cnccn1)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CCN1CCN(c2nc3ccccc3c3c2CCc2ccccc2-3)CC1 +COc1ccc(C(=O)N2CCC(=CC(=O)NC3CCN(Cc4ccc5cc(F)ccc5c4)C3)CC2)cc1 +Cn1cccc1C=Cc1cc(C=Cc2ccc(OCc3ccccn3)cc2F)n[nH]1 +COc1ccccc1N1CCN(CCCNc2ccccc2C(=O)c2ccccc2)CC1 +Cc1ccc(NS(=O)(=O)c2ccc(-c3c(C)c(CC(=O)O)cc4ccc(Cl)cc34)cc2)cc1 +CN(c1cc(F)c(F)c(F)c1)c1cnc2nc(N)nc(N)c2c1 +OC(CC1CCN(Cc2ccccc2)CC1)c1ccc(F)cc1 +N=C(N)c1cccc(-c2cccc(C(CCCNc3ccncc3)C(=O)O)c2)c1 +COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(CN3CCOCC3)n(C(C)COC(F)F)c12 +N=C(N)c1ccc(C2=NOC(CC(=O)NCC(NS(=O)(=O)c3ccccc3Br)C(=O)O)C2)cc1 +NC(=O)c1cccc(C2CC3CCC(C2)N3CCN(CC2CCCC2)C(=O)CO)c1 +Cc1cnc(C(=O)NC(Cc2nc(I)n(Cc3ccccc3)c2I)C(=O)N2CCCC2C(N)=O)cn1 +C#CCc1cc(OCOCCOC)c(C23CC4CC(CC(C4)C2)C3)cc1C(=O)C=Cc1ccc(C(=O)O)cc1 +COc1ccc(CC(=O)NC(=N)NC(Cc2ccccc2)C(=O)NCCN2C(=O)c3ccccc3C2=O)cc1OC +Cc1ccc(NC(=O)c2ccnc(N3CCOCC3)c2)cc1Nc1ccnc(OCC2CCCN(C)C2)n1 +N=C(NCCCC(N)CC(O)CCCN)N[N+](=O)[O-] +COc1cccc(S(=O)(=O)NCc2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)c1 +O=C(Nc1ncc(Br)s1)C1C(C(=O)NC2CCNCC2)C2CCC1C21CC1 +CCCN(CCN1CCN(C(=O)c2c[nH]c3ccccc23)CC1)C1CCc2c(O)cccc2C1 +O=C(c1cncc(CS(=O)(=O)c2c(Cl)cccc2Cl)c1)N1CCCCCCCC1 +Cc1[nH]c(C(=O)NC2CCN(c3ncc(C(=O)O)s3)CC2N=[N+]=[N-])c(Cl)c1Cl +Clc1ccccc1CSc1nnc(-c2ccc3c(c2)OCCO3)n1-c1ccccc1 +CC1(C)OC2C3CC(C2O1)N(c1cc(Cc2n[nH]c(=O)c4c2CCCC4)ccc1F)C3=O +CCCn1nc(-c2ccnc(Nc3cccc(S(N)(=O)=O)c3)n2)c2ccccc21 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4COCc4ccc(C(O)CO)cc4)C(C2)N(CC2CC2)CCC315 +COCc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2cccs2)cc1 +COC1CCC2(CC1)Cc1ccc(NC(=O)c3ccc(Cl)cn3)cc1C21N=C(C)C(N)=N1 +O=C(NC1CCN(CC2CCCCCC2)CC1)C(O)(c1ccccc1)C1CCC(F)(F)C1 +CC(C)(C)OC(=O)NC1CCN(C(=O)OC2C3CC4CC2CC(C(C)(C)O)(C4)C3)C1 +O=C(Nc1ccncn1)N1CCN(c2nc(-c3ccccc3)ns2)CC1 +CC(=O)N1CCC(n2cc(-c3cnc(N)c(-c4nc5ccc(Cl)cc5o4)c3)cn2)CC1 +NC(=O)c1cccc(-c2cc(Nc3ccc(OC(F)(F)F)cc3)ncn2)c1 +CCc1cc2ccccc2n1-c1nc2c(c(NCc3ccccc3)n1)CCCC2 +CCOc1cc2c3cc(OC)c(OC)cc3c[n+](C)c2c2cc(OC)c(O)cc12 +CCCCc1nn(CCC2CCCCC2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cccc(-c2cc(N)c(C(=O)c3cc(OC)c(OC)c(OC)c3)s2)c1 +COC(=O)C1OC(n2cc(-c3ccc(S(N)(=O)=O)cc3)nn2)C(O)C(O)C1O +O=C(O)CN1CCCCCCC(NC(CCc2ccccc2)C(=O)O)C1=O +COC(CCc1ccccc1)c1ccccc1OCC(O)CN1CCN(Cc2ccccc2)CC1 +O=C(c1ccccc1)c1ccc2c(c1)oc(=O)n2C(=O)NCCCCc1ccccc1 +N#Cc1ccc(-c2cc3c(o2)C(=O)N(Cc2ccccc2-c2cncnc2)c2ccc(C4CCNCC4)cc2C3(F)F)cc1 +Cn1cc(C2NC(c3nc(-c4ccc(F)cc4)c[nH]3)Cc3c2[nH]c2ccccc32)cn1 +O=C(c1cc(N=C=S)cc2ccccc12)c1cn(CCN2CCOCC2)c2ccccc12 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(C3=NCC(C)(C)O3)cc2n1Cc1ccccc1 +CC(C)Oc1ccc(Nc2ncc(NCCCO)c(=O)n2Cc2ccc(Cl)cc2)cc1F +O=C(O)CCCCN1C(=O)C(c2ccc(Cl)cc2)N(C(C(=O)O)c2ccc(Cl)cc2)C(=O)c2cc(I)ccc21 +COc1ccc(-c2ncc3c(n2)-c2[nH]c4c(c2CC3)C(=O)NCC4)cc1 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5[nH]c(C(N)=O)cc5c4)CC3)c2c1 +COc1cc(-c2cn(-c3nccc(N4CCOCC4)n3)cn2)cc(OC)c1O +Cc1cnc(Nc2cc(Cc3ccccc3)nc(NC3CCC(O)CC3)n2)s1 +COc1ccccc1C(=O)NC(=O)Nc1ccc(-c2ccccc2)c(C(C)C)c1 +Cc1ccc(C(=O)Nc2cccc(N(C)C)c2)cc1Nc1ncnc2cnc(N3CCN(C)CC3)nc12 +Cc1cc(S(=O)(=O)NC(=N)Nc2ccc(S(N)(=O)=O)cc2)c(SCc2cccc3ccccc23)cc1Cl +COC(=O)C1=C(c2ccc(CNc3nccc(C)c3NC(=O)CC#N)cc2)CCC1 +O=C(CCCOc1ccccc1)NCC(=O)N(O)CCCP(=O)(O)O +CN1CCN(c2nc(NCc3ccccc3)c3cc(Cl)ccc3n2)CC1 +CC12CN(C(=O)c3ccccc3)CC(C)(O1)C1C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C12 +O=C(O)CN(CC1CC(F)CN1)C(=O)c1ccc(-c2cnc3ccc(NCC4CC4)nn23)cc1 +Oc1cccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)c1 +O=C(CCCCCCC(=O)c1ccc(C(F)(F)F)cc1)NO +COc1ccc(F)cc1-c1ccc2c(c1)C(C(C)OCCc1ccccc1)=CC(C)(C)N2 +Cc1cc(=O)oc2c1ccc1oc(C(=O)c3ccccc3)c(-c3ccccc3)c12 +CC(C)c1nc2c(c(Nc3ccc(C(C)(C)C)cc3)n1)CCN(c1ncccc1C(F)(F)F)C2 +Cc1ncc(CCCN(C)C)cc1Nc1ncc2c(n1)-c1ccc(C(F)(F)F)cc1NC(=S)C2 +Nc1nc(Cl)c(-c2cc3ccccc3o2)c(NC2CC(CO)C(O)C2O)n1 +Cc1onc(-c2ccccc2)c1COc1ccc(C(=O)NC2CCCN(CC(=O)NC3CCOCC3)C2)cn1 +NS(=O)(=O)c1ccc2[nH]c(-c3ccc(C(=O)c4ccc(Cl)cc4)cc3)nc2c1 +CC(C(=O)NC1CCC1)c1ccc(OC2CCN(c3ncnc(OCC(C)(F)F)c3F)C2)cc1 +Nc1ncnc2c1nc(Br)n2C1OC2COP(=O)(O)OC2C1O +CC(C)N1C(=O)C(NC(=O)C(Cc2cccc(F)c2)NC(=O)OC(C)(C)C)CCc2ccccc21 +CCC(=C(c1ccccc1)c1ccc(C=CC(=O)N(C2CCCCC2)C2CCCCC2)cc1)c1ccccc1 +CONc1nc(C#Cc2ccc(F)cc2)nc2c1ncn2C1OC(CO)C(O)C1O +CCN(CC)CC(C(C)C)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +O=C(NC1CC1c1ccccc1)N1CCC(Oc2ccncc2)CC1 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+O=C(OCCCc1cccnc1)C1CCCN1C(=S)NC1CCCCC1 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4COC(=O)C(N)CC(C)C)C(C2)N(CC2CC2)CCC315 +O=c1c2cn[nH]c2c2ccc(-c3cccnc3N3CCCC3)cc2n1CC(F)(F)F +CC(=O)NCCNC(C)c1cnc2c(C)c(NC(=O)c3ccc(OCC4CC4)cc3)ccc2c1 +CC(C)N1CCN(C(CN2CCN(CCCc3ccccc3-c3ccc(OC(F)(F)F)cc3)CC2)c2ccc(F)cc2)CC1 +CN(CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21)CCc1ccccc1 +COc1ccccc1N1CCN(CCCC(=O)NC2CCCc3cccc(OC)c32)CC1 +C=CC(=O)Nc1cc(Nc2ncc(Cl)c(-c3cnn4ccccc34)n2)c(OC)cc1N1CCN(C)CC1 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(N2CCC(C(=O)O)CC2)cc1Cl +CCOC(=O)C1=C(c2ccccc2)NC(C)=C(C#N)C1c1ccccc1Cl +CCCCCCC(O)CCCC(O)C1CCC(C(O)CCC(O)C(O)CCCCCCCCCCCCC2=CC(C)OC2=O)O1 +CCOC(=O)c1sc(Nc2nc(NC)c3ncn(Cc4ccc(S(C)(=O)=O)cc4)c3n2)nc1C +CC1CCC(Oc2nc(N)c(C(N)=O)c(OC3CCCC3O)n2)CC1 +O=C(O)CCC(=O)N1CCc2cc(-c3noc(-c4ccc(OC(F)(F)F)cc4)n3)ccc21 +NS(=O)(=O)c1ccc(SCc2cccc(-c3ccccc3)c2)s1 +CC1(C)C2CC3OB(C(CCCCN)NC(=O)Cn4nc(CO)nc4Cc4ccccc4)OC3(C)C1C2 +CCNc1nnc(CSc2nc3sc4c(c3c(=O)n2CC)CCCC4)s1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)cc1)c1nnn(-c2ccc(F)c(F)c2)c1C(F)(F)F +COc1cc(Cl)cc(C(=O)Nc2ccc(Cl)cn2)c1NC(=O)c1scc(CN(C)CC(C)O)c1Cl +COC(=O)C(CNC(=O)c1ccc(-c2ccccc2)cc1)Cc1cccc(C(=N)N)c1 +CCCCOc1ccc(OCCCC)c(C(=O)C=Cc2ccc(Cl)cc2)c1 +OC1(c2ccc(OCc3ccccc3)cc2)c2ccccc2C2=NCCCN21 +Cc1c(-c2ccc(Cc3ccc(OC(F)(F)F)cc3)cc2)[nH]c2ncccc2c1=O +Cn1cc(Nc2ncc(Cl)c(NC3CCCC3C(N)=O)n2)cn1 +COc1ccc(C2=NN(CCCCCNCC(O)c3ccc(O)c(CO)c3)C(=O)C3CCCCC23)cc1OC +COc1cc2c(cc1OC)C(=O)C(=Cc1cccc(CN(C)C)c1)C2 +O=C1Nc2cccc(C3CCNCC3)c2C1=Cc1[nH]cc2c1CCNC2=O +Cc1c(C(O)CN2CCN(CC(O)c3ccc4c(c3C)COC4=O)CC2)ccc2c1COC2=O +COc1ccc(Nc2cc(Oc3c(C)cc(C)cc3C)n3ncnc3n2)cc1 +CCC(=O)c1cccc2c(C)c(C(=O)Nc3cc(C(C)(C)O)c4ccccc4n3)sc12 +O=C(NCc1ccncc1)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +O=C1N(Cc2cc(F)cc3c2OCOC3)CCCC12CCN(c1cnc3ccccc3n1)CC2 +COc1ccccc1N1CCN(c2ccncc2S(N)(=O)=O)CC1 +Cc1cnc(C)c(CCC2CCN(S(=O)(=O)CC3(N(O)C=O)CCOCC3)CC2)c1 +COC1COCCC1NC1CC2OCCC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +CC1CCc2nn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)cc21 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+NCc1ccccc1C1(O)CCN(C(c2ccccc2F)c2ccccc2F)CC1 +COc1ccc(Cl)cc1-c1cc(Nc2ccc(Br)cc2)nc(N)n1 +Nc1ncc(-c2cccc(C(F)(F)F)c2)nc1C(=O)NC1CCCC1 +Cc1nc(C)c(-c2ccnc(Nc3cccc(N)c3)n2)s1 +CC(C)(C)NCc1ccc2c(c1)CCCC2NC(=O)CC1CCCCN1S(=O)(=O)c1cccc2nsnc12 +O=C(CCN1CCCCC1)Nc1ccc(NC(=O)Nc2ccc(N(CCCl)CCCl)cc2)cc1 +O=c1cc(-c2ccnc(NC3CCOCC3)n2)ccn1C(CO)c1cc2cc(F)ccc2[nH]1 +CCCC(Nc1nc(N)nc(N)c1C#N)c1nc2ccc(F)c(Cl)c2c(=O)n1-c1ccc(N)nc1 +Brc1cccc(Nc2ncnc3cc4c(cc23)OCCCO4)c1 +CN(C)CCCNC(=O)c1cccc(NC(=O)Nc2ccc(N(CCCl)CCCl)cc2)c1 +COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCN(CCS(C)(=O)=O)CC4)nc12 +CCOCC(Cc1ccc(F)cc1)Nc1nc2cc(C(C)C)ccc2o1 +CC#CCn1ccc(C(=O)Nc2csc(C34COC(C)CC3CSC(N)=N4)n2)n1 +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2ccoc2)cc1 +CC(CC(=O)O)N1CCC(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +COc1cc(CNC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)ccn1 +Cc1cc(OC2CCN(c3nc(Nc4cc(C(C)(C)C)ccc4C)c4c(ncn4C)n3)CC2)ncn1 +CC(C)CC(=O)NCc1cccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)c1 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+C=CC(=O)N1CCCC1C(=O)Nc1cc2c(Nc3ccc(Cl)c(Cl)c3F)ncnc2cc1OCCOC +CC(c1ccc(-c2cccc(=O)n2C)cc1)N1CCC(CCCO)(c2ccccc2)OC1=O +CC(=O)N1CCN(C(=O)C2CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC2)CC1 +C=C1C(=O)C23CCC4C5(C)CCCC4(OC5=O)C2(C)CCC1(OC)C3 +COc1ccc(C2=NN(C(=O)c3cncc(Br)c3)C(c3ccc(Cl)cc3)C2)cc1 +O=C(NCC1CCOCC1)C1CCN(c2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +c1cc2[nH]cc(CCN3CCC3)c2cc1-n1cnnc1 +CC(C)c1ccccc1OCCN1CCC(NS(=O)(=O)c2cccc(Cl)c2)C1 +O=C(Cc1cccc2cnccc12)Nc1scnc1-c1nc[nH]n1 +CCC(=O)NC(c1cccs1)c1cc(Cl)c2cccnc2c1O +Fc1ccc(-c2nc(F)ccc2-c2ccc(OCc3ccc4ccccc4n3)cc2)cc1 +N#CC1CSCN1C(=O)CN(N)C1CCN(CC(=O)Nc2ccc(S(N)(=O)=O)cc2)CC1 +CCCn1c(=O)c2nc(C=Cc3cc(F)cc(F)c3)[nH]c2n(CCC)c1=O +CC1(C)COP(=O)(Nc2ccc(-c3cc4ccc(OS(N)(=O)=O)cc4oc3=O)cc2)OC1 +CCCn1c(=O)c2nc(-c3ccc(OCc4noc(-c5ccc(C)cc5)n4)cc3)[nH]c2n(CCC)c1=O +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1OCCNC(C)(CO)CO +CC(C)CCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1C(=O)O +COc1ccc(CN(C)S(=O)(=O)c2cccc(Oc3cccc(-c4c(C(C)C)nc5c(Cl)cccn45)c3)c2)cc1 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+COCCOCCOCCOCCCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +Fc1ccc2c(c1)nc(-c1ccccn1)n2-c1ccc(OCCCN2CCCCC2)cc1 +Cc1c(NC(=O)c2cc([N+](=O)[O-])ccc2Cl)cccc1-c1nc2ccccc2s1 +CN1C(=O)C(c2ccncc2)(c2cccc(-c3cccc(F)c3)c2)N=C1N +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1cc2cc(-c3cnn(CC(C)(C)O)c3)ccc2cn1 +CC1(C)CCC2(C(=O)O)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(CO)C5CCC43C)C2C1 +O=C(CCC1CCCN(Cc2ccc3c(c2)OCCO3)C1)NCc1ccc(F)c(F)c1 +O=C(NCC12CCC3(O1)C1Cc4ccc(O)cc4C3(CCN1Cc1ccccc1)C2)c1ccccc1 +CC(NC(=O)C(C#N)=Cc1ccc(O)c(O)c1)c1ccccc1 +CC(NC(C)(C)C)C(=O)c1cccc([N+](=O)[O-])c1 +CC(c1ccccc1)N1CCCC(CNCc2cc(C(=O)O)ccn2)C1=O +CCCCN(CCO)C(=O)C1=Cc2ccc(C(=O)Nc3cccc(C)c3)cc2N=C(N)C1 +CCOC(=O)c1cnccc1Nc1nc(-c2nn(Cc3ccccc3F)c3c2CCC3)ncc1Oc1ccccc1C(=O)OCC +Cc1nc(N)ncc1-c1ccc(-c2ccccc2S(=O)(=O)NC(C)(C)C)cc1F +COc1cccc(-c2cc3c(C)nc(N)nc3n(C3CCCC3)c2=O)c1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(-c4cccc(S(C)(=O)=O)c4)cc23)c1F +N=C(N)c1ccc(-c2ccc(C3=CCC(O)(CC(=O)O)CC3)cn2)cc1 +N=C(N)NCCCC1NC(CNC(=O)C=Cc2c(F)cccc2Cl)CCN(CC(c2ccccc2)c2ccccc2)C1=O +O=[N+]([O-])c1cn2c(n1)OCC(OCc1ccc(-c3ccc(C(F)(F)F)cc3)cn1)C2 +Nc1cccc(-c2cc(COCC3(c4ccccc4)CCNCC3)cc(C(F)(F)F)c2)c1 +Cc1ccc(C2COC(=O)N2c2ccn3ncc(-c4ccc(-c5nc[nH]n5)c(F)c4)c3n2)cn1 +CC1CCc2cc(-c3ncccc3C#N)ccc2N1C(=O)c1ccc(O)cc1O +OC1(CCCc2ccc(-c3nnn[nH]3)cc2)CCN(CC2CN(CC3CCCCC3)CC2c2ccccc2)CC1 +O=C(CCN1CCN2c3ccccc3CCC2C1)c1ccc(F)cc1 +O=S(=O)(Nc1ccc(NS(=O)(=O)c2cccc(F)c2)cc1)c1cccc(F)c1 +CC(C)(O)C#Cc1cc2c(cc1F)C1CC(C1)c1c-2nc(C(N)=O)n1C(F)F +CC1(C)OC(=O)N(C2CCC(NC(=O)c3ccc[nH]3)CC2)C1c1ccccc1 +CN(C)Cc1ccc2nc(NC(=O)NN=Cc3cn(Cc4ccccc4)c4ccccc34)sc2c1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(N1C(=O)C=CC1=O)C2 +CC(=O)OCCn1c(Sc2nc3cccc(Cl)c3s2)nc2c(N)ncnc21 +CNCc1csc(NC(=O)c2cc(C(C)(C)C)nn2Cc2ccccc2)n1 +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1c(Oc2ccccc2)cccc1N1CCCCCC1 +CN1C(=O)OC(C)(C)c2cc(Nc3cccc(Cl)c3Cl)ccc21 +CCCCc1cc(OC2CCN(CCNS(=O)(=O)CC)CC2)c2ncccc2c1 +Nc1ccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2sc3ccccc3c2Br)cc1 +CC(C)(O)c1cnn2c(-c3ccc(F)c(-c4ccc(F)cn4)c3)cnc2n1 +Cc1cccc(N2CCN(CCCCNc3nc(NCc4ccco4)c4ccccc4n3)CC2)c1C +O=c1cc(C(F)(F)F)c2cc(NC3CCCC3)ccc2[nH]1 +CC(C)CC(C)(N)COc1ncc(-c2ccnc3ccccc23)cc1C(F)F +Cc1nn(Cc2c(Cl)cccc2C2CC2)c2cc(-c3nnn[nH]3)cnc12 +O=C(NO)c1cnc(Nc2nnc(-c3ccc(O)cc3)o2)nc1 +CN1CCCC1c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +CN1C(=O)CCN(C2CCCC2)c2nc(Nc3ccc(N4CCC(O)CC4)cn3)ncc21 +Cc1cc(C(N)=O)ccc1-c1c(CCC(=O)O)ccn1-c1ccc(-n2ccnc2)cc1 +O=C(c1cccc(Cl)c1Cl)N1CCc2c(ncnc2-c2ccn[nH]2)C1 +COC1OC(C(O)C(C)(C)O)CC1C1CCC2(C)C3=CCC4C(C)(C)C(=O)CCC4(C)C3CCC12C +COc1ccc(C2CC2COc2cc(N(Cc3ccc(C)nc3C)Cc3ccc(C)nc3C)c(=O)n(C)n2)nc1 +O=C(c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1ccc(CN2CCOCC2)cc1)C1CC1 +Cc1cccc(S(=O)(=O)Nc2ccc(C=CC(=O)NO)cc2)c1 +CCN(CC)CCCS(=O)(=O)NC(CCc1ccccc1)c1nc(-c2ccc(OC)cc2)n[nH]1 +COc1ccc2c(c1)c(C=C1Oc3cc(O)cc(O)c3C1=O)c(C)n2CCCN1CCOCC1 +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(NC4CCN(c5ccc(C(=O)NO)cc5)CC4)ccc3OCC)nc12 +O=C(CNC(=O)c1ccccn1)NC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(CC1CC1)C2C5 +CCC(CC)Oc1cc(C)nc(Oc2c(C)cc(C)cc2C)c1[N+](=O)[O-] 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+Cc1ccc(CN2CCNCC2)cc1NC(=O)c1ccc(Nc2nc(-c3ccc(OC(F)(F)F)cc3)c3cccn3n2)cc1 +O=C(NC(Cc1ccc(OCCc2cccc(NC3CCCC3)n2)cc1)C(=O)O)c1c(Cl)cccc1Cl +COc1cc2c(cc1OC)C(=O)C(Oc1ccc(C(C)N3CCCC3)cc1)C2 +CCc1nc(NC(=O)NS(=O)(=O)c2cc(C)c(CCO)s2)sc1OC +CCCC(CC(O)N1CCCC(Cc2ccc(F)cc2)C1)NC(=O)Nc1cccc(-c2nnnn2C)c1 +N#Cc1ccc(Cn2nc3c(-c4ccncc4)c(-c4ccc(Cl)cc4)c(=O)n(Cc4ccc(C#N)cc4)n3c2=O)cc1 +COc1ccc(C(F)(F)F)cc1NS(=O)(=O)c1ccc(OC)c(N2CCNCC2)c1 +NC(CCC(=O)Nc1cc(Cl)cc(S(=O)(=O)O)c1O)c1nnc(Cc2ccccc2)o1 +COc1cc(C(=O)C=Cc2cccc3[nH]ccc23)cc(OC)c1OC +CC(=O)N1CCN(c2cc(-c3cc(Cl)c4c(N)ncnn34)ccc2C(F)(F)F)C(=O)C1(C)C +CNC(=O)CCCCCC(NC(=O)c1cncs1)c1ncc(-c2ccc3[nH]ncc3c2)[nH]1 +CN1CCN(C(=O)C(CNC(=O)c2ccc(Cl)s2)NS(=O)(=O)c2cccc(N3CCCC3=O)c2Cl)CC1 +CCOc1cccnc1C(=O)NC1CCCC1(C)Nc1cnc(C(F)(F)F)cn1 +CC(=O)c1cccc(-c2cccc(-n3cc(C(=O)Nc4nccc(Cl)c4Cl)c(=O)c4cccnc43)c2)c1 +CC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2c(F)cccc2C(N)CC(C)C)CC1 +CS(=O)(=O)Nc1ccc(Nc2c3ccc(Cl)cc3nc3cc(Cl)ccc23)cc1 +Cc1ccc2c(C3CCN(CCN4CCN(C(C)C)C4=O)CC3)cn(-c3ccc(Cl)cc3)c2c1 +CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4cn[nH]c4)cc3)n2)c(=O)c1=O +CC(C)Nc1ncc2c(n1)CN(C(=O)NC1(c3ccc(Cl)c(Cl)c3)CCNCC1)CC2 +COc1ccc(CN2C(=O)c3ccccc3C2=O)cc1C(=O)Nc1ccccc1N1CCOCC1 +CN(Cc1ccccc1)Cc1ccc(C=C2CCc3cc(OCCCCCN4CCCCC4)ccc3C2=O)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(Cl)c(Cl)c2)CC1 +O=C(C=Cc1ccc(O)c(O)c1)OCC(OC(=O)C=Cc1ccc(O)c(O)c1)C(=O)O +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1CCCCC(=O)NO +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(OC(F)F)c1 +Cc1ccccc1S(=O)(=O)N1CCC(N2CCC(O)(c3ccc(Cl)cc3)CC2)CC1 +O=C(NCCCO)C(Cc1ccc(Cl)cc1)NC(=O)C1(c2ccc(Cl)cc2)CC1 +N#Cc1ccc(N(CC2CCc3cc(OS(N)(=O)=O)ccc3C2)n2cnnc2)cc1 +COc1cc2c(cc1-c1c(C)noc1C)ncc1nc(C(F)(F)c3ccccn3)n(CC3CCOCC3)c12 +CC(C)CC(NC(=O)C(Cc1ccc(O)cc1)NC(=O)N1CCOCC1)B(O)O +CN(C)CCCNC(=O)c1cccc(-c2cc(Cl)c3c(c2)C2(CCCCC2)NC(=O)N3)c1 +O=C(O)COc1cccc(Oc2ccc3c(c2)CC(NCC(O)c2cccc(Cl)c2)CC3)c1 +NS(=O)(=O)c1ccc(N2C(=O)c3c(Br)c(Br)c(Br)c(Br)c3C2=O)cc1 +Cc1csc(-c2nc(CN3CCCC3=O)[nH]c2-c2ccc3ncsc3c2)n1 +FC(F)(F)c1ccccc1CNC1C2CCN(CC2)C1C(c1ccccc1)c1ccccc1 +CCCCn1c(=O)c2nc(-c3ccc(OCC(=O)O)cc3)[nH]c2n(CCCC)c1=O +CC1(C)OCC(=O)Nc2ccc(-c3ccc(F)cc3)cc21 +CN1CCN(Cc2cccc3c2c(Br)cn3S(=O)(=O)c2ccc(F)cc2)CC1 +CCC1(c2ccccc2)CC(c2ccc3c(=O)n(-c4ccc(F)cc4)c(CCCCC(=O)O)nc3c2)=NO1 +CCc1cc(NC(=O)NC(C)C(O)CN(CC)C(C)CCc2ccc(F)cc2)cc(-c2nnnn2C)c1 +COc1ccc(C(C)(CC(=O)O)NC(=O)C2CCN2S(=O)(=O)c2cc(Cl)cc(Cl)c2)cc1 +[H]c1cccc([H])c1-c1nnc(CC2CCCN2C(=O)c2nc(C)sc2-c2ccccc2F)o1 +C=C(C(=O)OCC)C(OCCC(=O)OCC)c1ccc(Cl)cc1Cl +CCCCc1nc2ccn(Cc3cccc(Cl)c3)c(=O)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CCc1c(C)[nH]c(=O)c(-c2ccco2)c1Oc1cc(C)cc(C)c1 +CN(CCc1ccccc1)C(=O)Cc1cc(C=CC(=O)O)cc2c(OCc3ccccc3)cccc12 +COc1ccc(NCCNC(=O)C2(Nc3cccc(-c4ccccc4)c3)CCCCC2)cc1 +O=C(CCCc1c[nH]nn1)NC1CCCN(C(=O)OCc2cc(Cl)cc(Cl)c2)CC1 +Cc1cc(S(=O)(=O)NC(CC2CC2)C(=O)NO)ccc1F +COc1ccccc1NC1=C(N2CCCCC2)C(=O)c2ccccc2C1=O +CC(C)c1nc(C(c2ccccc2)c2ccccc2)cc(-c2ccc(F)cc2)c1C#CP(=O)(O)CC(O)CC(=O)O +CC(C)C(NC(=O)Cn1c(-c2ccc(N)cc2)ncc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F +CCOCCOc1ccc(S(=O)(=O)N2CC(O)C(O)C(O)C2C(=O)NO)cc1 +CCc1ccc2c(c1)nc(Cn1c(=O)n(C(C)C)c3ccccc31)n2CCC(C)C +CCc1ccc(NC(=O)Nc2ccc(S(=O)(=O)Nc3ccc(CC(C)(C)N)cc3)cc2)cc1 +CC(C)CC(NC(=O)Nc1ccc(C(F)(F)F)cc1)C(=O)NC(C)(C)C(=O)O +Cc1ccc(-n2nc(C3CCN(C4CCC5CC54)CC3)cc2NC(=O)c2cnn3cccnc23)cc1 +[N-]=[N+]=NCc1cccc2c1nc(-c1c(F)cccc1F)n2Cc1c(F)cccc1F +O=C(Nc1cccc(-c2cn3ccnc3c(NCc3ccncc3)n2)c1)Nc1cc(C(F)(F)F)ccc1O +Cc1n[nH]c(C(=O)O)c1Cc1cccc(-c2cccc(F)c2)c1 +CC(C)(C)c1cc(C=NNC(=O)c2ccccc2)c(O)c(C(C)(C)C)c1 +CC(C)N1CC(N=CC(C=N)c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)C1 +CC(C)(C)Cn1c2ccccc2c2cc(NC(=O)N3CCOCC3)ccc21 +CC1(C)CNc2cc3nc(O)cc(C(F)(F)F)c3cc21 +c1ccc(-c2[nH]c3ccccc3c2C2CCCNC2)cc1 +Cc1ccc(NC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1 +CC(C)n1c(CCC(O)CC(O)CC(=O)O)c(-c2ccc(F)cc2)c(-c2ccc(F)cc2)c1C(=O)Nc1ccccc1 +CC12CC3CC(C)(CC(C1)C3NC1CCN(Cc3ccc(Cl)cc3F)CC1)C2 +CCN1CCN(C(N=O)c2ccc(C#CC3(CN4Cc5ccc(OC)cc5C4=O)NC(=O)NC3=O)cc2)CC1 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+O=C(CCNc1ccccc1)Nc1ccc2nc3c4[nH]c5ccccc5c4ccn3c(=O)c2c1 +O=C(C1CCCN1)N1CCc2c(nc(O)c3ccccc23)C1 +CC(=O)Nc1cccc2c1C(=O)c1c(-c3sccc3C)n[nH]c1-2 +CCCCCC(C)N(Cc1ccc(OCC(C)C)cc1)C(Nc1ccc(OC)cc1OC)=C1C(=O)OC(C)(C)OC1=O +Nc1ncc(-c2ccc(C3(c4noc(-c5ccnnc5)n4)CCC3)cn2)cn1 +CNCC(O)C(c1cccc(F)c1)n1ccc2cccc(Cl)c21 +CCCC(NC1(C(=O)NC(Cc2nc(-c3ccccc3)co2)C(=O)O)CCCC1)C(=O)O +COc1cc2nc(-c3cccnc3)cc(O)c2cc1-c1cnco1 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-n2nccn2)c1 +Cc1nc(N(C)c2ccc(OC(C)C)cc2)c2ccccc2n1 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(OC)c(F)c1 +CCCC(NC(=O)C(C#N)=Cc1cccc(Br)n1)c1ccccc1 +Cc1ccc(C(Br)c2ccnc(Nc3ccc(C#N)cc3)n2)cc1 +Cc1cc(C)c(S(=O)(=O)NC(C)Cc2c[nH]c3cc(F)ccc23)c(C)c1 +COc1cc(C(=O)c2oc3cccc(O)c3c2C)cc(OC)c1OC +Nc1ccc(S(=O)(=O)Nc2nc(-c3cc(C(F)(F)F)ccc3F)cs2)cc1 +COc1cccc(Sc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)noc2CCCC=NO)c1 +Cc1ncc(C)n2nc(CCc3cn(C)c(-c4cscn4)n3)nc12 +O=C(O)c1ccc(COc2cccc(-c3c(C(=O)c4ccccc4)cnc4c(C(F)(F)F)cccc34)c2)cc1 +CCCCCNC(=O)c1coc(C2C3CCC(O3)C2Cc2ccccc2CCC(=O)O)n1 +CC(C)(N)CNc1cc(-c2ccc[nH]2)c2c3c(ccc(F)c13)NC2=O +CCCN1CCC=C(c2c[nH]c3ccc(OC)cc23)C1 +C=CCNc1nccc(-c2[nH]c(C3OCC(C)(C(=O)N4CCOCC4)CO3)nc2-c2ccc(F)cc2)n1 +O=C(CCCCCCC(=O)NNC=Cc1cc(O)ccc1O)NO +Cc1cc(S(=O)(=O)NCc2cccnc2)cnc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +CSc1nc(-c2ccc(F)cc2)c(-c2ccnc(NC3CCc4ccccc43)c2)[nH]1 +c1cc2c3cnc(Nc4ccc(NCC5COCCN5)nn4)nc3n(C3CCCC3)c2cn1 +COCCc1nc2c(c(C(F)(F)F)n1)CCN(C(=O)CC(N)CN1C(=O)CCC(F)(F)C1O)C2 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CCN)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +CC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1cccc(C(N)=O)c1)C(=O)O +CC(C)c1nn(-c2ccccc2)c(-c2ccc(F)cc2)c1CCC(O)CC(O)CC(=O)O +NC(=S)Nc1cccc(OCCCCCOc2ccc(N3CCCCC3)cc2)c1 +Cc1c(C(N)=O)sc2ncnc(Nc3ccc(F)cc3OC3CCN(Cc4ncon4)CC3)c12 +O=c1ccc(OCCCN2CCCCC2)nn1-c1ccc(Cl)cc1Cl +Cc1cc(Nc2nc(Nc3ccccc3S(=O)(=O)C(C)C)c3c(C)c[nH]c3n2)c(OC(C)C)cc1C1CCNCC1 +O=C(C=Cc1ccc(O)cc1)c1ccc(OC2OC(CO)C(O)C(O)C2OC2OCC(O)(CO)C2O)cc1O +O=C(Cc1ccccc1F)Nc1nnc(CCSCCc2nnc(NC(=O)Cc3ccccc3F)s2)s1 +NC(CC(=O)N1CCc2n[nH]c(C(F)(F)F)c2C1)Cc1cc(F)ccc1F +CC(=O)CCCC(=O)NC1N=C(c2ccccc2)c2ccccc2N(CC(=O)NCCc2ccccc2)C1=O +Cc1c(Cl)ccc2c1NC(=O)C2(c1ccc(O)cc1)c1ccc(O)cc1 +COC(C)CNC(=O)c1nc(N2CCC(NC(=O)c3[nH]c(C)c(Cl)c3Cl)C(OC)C2)sc1C(=O)O +COC(=O)c1c(Cc2ccc(C(=O)NC3CCC(O)CC3)cc2)c(=O)c2ccc(C)nc2n1-c1ccccc1 +CC(=O)NCCNc1cccc(Nc2nc3ccc(C(=O)Nc4c(C)cccc4Cl)cc3s2)n1 +N#CC(Cc1ccc(-c2ccc3c(c2)CC(=O)N3)cc1F)NC(=O)C1NC2CC1C1CC21 +COc1cc(C(N)=O)c2ncnc(NC(CN(C)C)c3ccccc3OC)c2c1 +Nc1cnc(-c2ccc(C3CCC3)c(OCC(O)Cn3cnccc3=O)c2F)cn1 +Cc1ccc(C(=O)Nc2cccc(N3CCOCC3)c2)cc1-c1ccc2[nH]c(=O)ccc2c1 +COc1ccc(OC)c(Sc2ccc3nnc(-c4ccccn4)n3n2)c1 +N#Cc1ccnc(-c2ncc(C(=O)N3CCN(C(=O)c4ccc(Br)cc4)C(c4ccc(Cl)cc4)C3)o2)c1 +N=C(N)c1cccc(N(CCCc2ccc(-c3ccccc3S(N)(=O)=O)cc2)CCOc2ccccc2)c1 +Cn1cncc1C(OCc1ccc(C#N)nc1-c1ccc2ccccc2c1)c1ccc(C#N)cc1 +Cc1cccc(-n2nc(C(N)=O)c3ccc4[nH]ncc4c32)c1 +COc1cc(C(=O)c2c(-n3ccnc3)[nH]c3ccccc23)cc(OC)c1OC +Cc1noc(CNC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)n1 +C=CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC=C)C1C=Cc1ccccc1OC +COc1cccc(-c2cc(NC(=O)NNc3ccc(N(CCCl)CCCl)cc3)c3cc4c(cc3n2)OCO4)c1 +COc1ccc2c(c1O)C13C=C(C#N)CCC1(O)C(C2)N(C)CC3 +COc1ccc(C(=N)NC(C)C)cc1-n1cc(-c2cccc(C(=N)NC(C)C)c2)nn1 +O=C(Cc1ccc(O)c(F)c1)NN=C1C(=O)Nc2c(Cl)ccc(Cl)c21 +CN1CCC(S(=O)(=O)c2c(Cl)ccc(NC(=O)Nc3cccc(Cl)c3Cl)c2O)CC1 +CN1C2CCC1C(c1cc(-c3ccc(F)cc3)no1)C(c1ccc(Cl)cc1)C2 +NS(=O)(=O)c1ccc(-n2cc3c(n2)-c2ccc(Cl)cc2SC3)cc1 +Cc1cccc(-n2nnc3c2CCN(C(=O)c2cccc(C(F)(F)F)c2Cl)C3C)n1 +CCNC(=O)Nc1cc2ccc(-c3cc(F)ccc3C)cc2cn1 +Cc1cccc(OC(c2ccc(Cl)c(Cl)c2)C2CNC2)c1 +COCCN1CC(=O)C(NC(=O)C(Cc2ccccc2)NC(=O)OCc2ccccc2)CC1=O +CCCN(CCOC)c1nc(C)nc2c1c(C)nn2-c1ccc(C(N)=O)nc1C +Fc1cc(F)c(CN2CCN(c3nc4cnccc4nc3NC3CC3)CC2)cc1F +CN1CCCC1Cc1c[nH]c2ccc(C3=CCN(C(S)=NC4CCCCC4)CC3)cc12 +CCC(C)(C)Cc1c[nH]c(CCc2ccc(-n3cncn3)cc2)n1 +O=C(O)CC1CCN(C(CC2CCC2)c2ccc(C(F)(F)F)nc2)C(c2ccc(C(F)(F)F)cc2)C1 +O=C(Nc1nc(-c2ccc(F)cc2)cs1)c1ccc([N+](=O)[O-])s1 +COc1ccc(-c2ccc(C(=O)O)cc2)cc1OC1CCCC1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCC3=CC(=O)CCC3(Cc3ccc(F)cc3)C2)cc1 +CCNc1nc2cc3c(cc2s1)CC1C2CCCCC32CCN1CC1CCC1 +CCN(CC#N)C(=O)C1CC(C(=O)N2CCOCC2)C(C)N1 +COc1cc(OC)cc(-c2cc3nc(C)ccc3cn2)c1 +Cc1nc(S(C)(=O)=O)ccc1Oc1ncnc(OC2CCN(C(=O)SC3CC3)CC2)c1F +O=C(NC(c1ccc(Cl)cc1)c1cc(Cl)c2cccnc2c1O)c1cccnc1 +CNC(C)(C)CC=CC(=O)N(C)C(Cc1ccc2ccccc2c1)C(=O)N(C)Cc1ccccc1 +O=C(Nc1c(Cl)cccc1Cl)C1c2ccccc2COc2ccc(Br)cc21 +Cc1cc(N2C(=O)c3nn(C4CN(C)C4)c(C)c3C2c2ccc(Cl)cc2)cn(C)c1=O +COc1cc2c(cc1O)C1CC(O)(c3ccc(OC(F)(F)F)cc3)CCN1CC2 +O=S(=O)(c1ccc(F)c(F)c1)N1CCCC(Cn2ccnc2)C1 +CCCCCc1ccccc1-c1ccc(OC(Cc2ccccc2)C(=O)O)cc1 +Cc1cc(C(=O)Nc2ccc(C(=O)N(C)C)cc2)n(-c2ccc3cc(Cl)ccc3c2)n1 +CCCCCCCCCCCCc1noc(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccccc2)n1 +NS(=O)(=O)c1ccc(COC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +Cc1c(C(=O)c2cccc3ccccc23)c2ccccc2n1CCC1CCCCC1 +N#CCc1c(C(=O)NCc2ccc(Cl)cc2Cl)nn(-c2ccccc2Cl)c1-c1ccc(Cl)cc1 +N#Cc1c(N=Cc2ccc3ccccc3c2)c(C(=O)Nc2ccc(Cl)cc2)n2c1CCC2 +O=CNC1CCC(CCN2CCC(c3cccc4c3CCO4)CC2)CC1 +NC(=O)C1=CC(C2CCCCC2)CC(OCc2ccc(CO)cc2)O1 +CCC(NC(=O)c1c(N=[N+]=[N-])c(-c2ccccc2)nc2ccccc12)c1ccccc1 +COc1ccc(N(C)c2nc(C)nc3[nH]ccc23)cc1 +CCCCCC(C)(C)NCC(O)C(Cc1ccccc1)NC(=O)c1cc(NCC)cc(N2CCCC2=O)c1 +CCn1c(=O)c(C(=O)NCc2ccc(F)cc2)c(O)c2ncsc21 +CC1CNCC(C)N1C(=O)c1cn2c3c(cccc13)OCC2C1CCCCC1 +CC(C)COc1ccc(Sc2nc(N)nc3c2ncn3CCOCP(=O)(OCC(F)(F)F)OCC(F)(F)F)cc1 +COc1ccc([N+](=O)[O-])cc1OCC1CN(Cc2ccc(Cl)cc2)CCCO1 +COc1ccc(OC)c2c1c(OC)cc1c(=O)c(OCCOCCOCCOCCOC(=O)CN)c(-c3cccc(F)c3)oc12 +CCC(=O)N(c1ccccc1)C1CCN(CCC(C(=O)N2CCCC2)(c2ccccc2)c2ccccc2)CC1 +O=C(COc1ccc(Br)cc1Cl)NC1CCN(Cc2ccccc2)CC1 +Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CCCC(F)(F)C3)ns2)n1 +CN(C(=O)Cc1ccc(CNS(=O)(=O)Cc2ccccc2)cc1)C(CN1CCC(O)C1)c1ccccc1 +COc1ccc(Cn2cnc(N)c3nc(C(C)(C)COc4ccc(C(F)(F)F)cc4)nc2-3)cc1OC1CCCC1 +CN(CCOc1ccc(NS(C)(=O)=O)cc1)CCc1ccc(NS(C)(=O)=O)cc1 +Cc1ccc(COc2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)cc1 +COc1ccc(Oc2cc(Nc3cc(Cl)ccc3C(N)=O)c(C(F)(F)F)cn2)cc1 +COc1cc(OC)cc(N(CCCc2ncccc2OC)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CCCCCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCN +O=C(Cc1cccc(Cl)n1)Nc1ccc(CCNCC(O)COc2ccccc2)cc1 +Cc1ccc2nc(NC(=O)N3CCN(c4ncc(C(O)C(C)O)cc4F)CC3)sc2c1 +O=C(C=CC#Cc1cccc(O)c1)NC1=C(C(=O)O)CCCC1 +COc1cccc(Cn2cc(C)c3cc(F)cc(C=CC(=O)NS(=O)(=O)c4cc(F)c(F)cc4F)c32)c1 +CN(C)CCC(=O)OCc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F +CC(C)Oc1cccc(-c2c[nH]c3ccc(-c4nnc(NC5CCCNC5)s4)cc23)n1 +OC1C2CC3CC1CC(C2)C3(Cc1nnn[nH]1)c1ccc(-c2ccccc2)nc1 +COC1(COc2cccc3ccc(-c4nnc5cc(C)ccn45)nc23)CCNCC1 +CCc1csc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)n1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2ccc(O)cc12 +Oc1ccc2c(c1)OCc1c-2nc2ccc(O)cc2c1-c1ccc(C(F)(F)F)cc1 +COc1cc(C(=O)NCC(c2cccnc2)N2CCN(c3ccc(F)cc3)CC2)cc(OC)c1OC +COc1ccc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cc1-c1c(Br)cnn1C +O=C(CCCCCn1cc(-c2ccc3ncnc(Nc4ccc(OCc5nccs5)c(Cl)c4)c3c2)nn1)NO +CC1C(=O)c2nn(C(C)(C)C)cc2OC12CCN(C(=O)c1ccc3[nH]ncc3c1)CC2 +CCN(CC1CCNCC1)c1ccc2c(SC)nn(-c3ccccc3)c2c1 +CCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3ccccc3C(F)(F)F)cc2o1 +Cc1c(COc2ccc(CC(C)NCC(O)c3cc(O)cc(O)c3)cc2)no[n+]1[O-] +O=C(Nc1cccc(Cl)c1N1CCCC1)c1cccc(-c2cc3ccccc3oc2=O)c1 +Cc1cc(CN2CCCC(O)C2)ccc1C(=O)Cn1ncc(OCc2ccccc2)cc1=O +CCOC(=O)CC(C)(O)CC(O)CSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1 +O=C(c1cc(O)c(O)c(O)c1)c1ccc(O)c(O)c1O +CNC(=O)COC(=O)C1CCCN1C(S)=Nc1ccc(S(N)(=O)=O)cc1 +CN1CCC2(c3cccc(O)c3)CCC(=Cc3ccc(Cl)c(Cl)c3)C1C2 +CNCCN1CCC(OCc2ccc(C3CCCCC3)cc2)CC1 +CCc1[nH]c2nc(Sc3cnc4c(c3)c(=O)ncn4C)nc(N3CC4C(N)C4C3)c2c1Cl +COc1cc(-n2cnc3cc(-c4ccc(Cl)cc4)sc3c2=O)ccc1OCCN1CCCC1 +O=C(NC1CCN(Cc2ccc3sccc3c2)CC1)c1cc(=O)c2ccc(F)cc2o1 +CN1CCN(c2ccc3ncc(C(N)=O)c(Nc4ccc(F)cc4F)c3c2)CC1 +O=C1C2CCCN2C(=O)N1CCCCNCCc1cccc2ccccc12 +CN(C)c1ccc(S(=O)(=O)N(CCC2CC2)c2cc3ccccc3s2)cc1 +Nc1ncc(-c2cc(N3C4CCCC3CCC4)nc(N3CC4CC3C4)n2)cn1 +CCCCCCCCCCCCc1cc(CC(=O)Nc2c(OC)cc(OC)cc2OC)on1 +COc1cc(C(=O)NCN2CCC(c3cccc[n+]3[O-])CC2)ccc1Cl +Cc1ccc(CN(CCNC(=O)c2ccc(CNS(=O)(=O)c3cccc(C)c3)cc2)C(C)C)cc1 +CCCCc1sc(-c2ccc(OCCN3CCCC3)cc2)nc1-c1ccc(Oc2ccc(Cl)cc2)cc1 +O=S(=O)(Nc1ncc(Cl)s1)c1cc(F)c(Oc2ccc(F)cc2-c2cn[nH]c2)cc1F +Cc1cccc(Nc2nc(NC3CCCNC3)ncc2C(N)=O)c1 +CCCCCCCCCCCCc1cn(C(C(=O)Nc2c(OC)cc(OC)cc2OC)c2ccccc2)cn1 +CC1CC(O)C2(O)OC3CC4(C=O)C(CCC5C4CC(O)C4(C)C(C6=CC(=O)OC6)CCC54O)CC3OC2O1 +Cc1nc(NC(=O)CN2CCC(N(N)CC(=O)N3CSCC3C#N)CC2)sc1C +OC1(CN2CCCC2)CCN(c2ncnc3scc(-c4ccccc4)c23)CC1 +CNC(=O)c1cnc(Nc2ccc(OC)c(F)c2)cc1NC(c1ccccc1)C(O)CO +O=C(Nc1ccccc1)N1CCN(Cc2ccc3ccc4cccc5ccc2c3c45)CC1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#CC4CC4)nc31)C(O)C2O +O=C(O)COCC1CCC(COC(=O)N(c2cccc(F)c2)c2ccc(F)c(F)c2)CC1 +CNCCN1CCC(NCc2cccc(OC(F)(F)F)c2)CC1 +Cc1nc(C)c(CNc2nc(OCCCc3ccccn3)nc(Cl)c2C)s1 +C#Cc1cccc(Nc2ncnc3ccc(OCCCCOP(N)(=O)N(CCCl)CCCl)cc23)c1 +CCNC(=O)C(CNCc1ccc(C)cc1C)NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 +CNS(=O)(=O)Nc1cccc(Cc2c(C)c3ccc(Oc4nccs4)cc3oc2=O)c1F +O=C(OC1CN2CCC1CC2)N1CCc2ccccc2C1c1ccccc1 +Cc1cc(C(CC(c2ccc(-c3ccc(C(=O)O)cc3)cc2)c2ccccc2C)=NO)ccn1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)C1CC1 +CCc1cc(=O)oc2nc(OCc3ccc(C(F)(F)F)cc3)[nH]c(=O)c12 +CCNC(=O)CCc1nc(-c2ccc(C(C)(C)C)cc2)no1 +CC(C)CCn1c(Cn2c(=O)n(Cc3ccc(CP(=O)(O)O)cc3)c3ccccc32)nc2ccccc21 +CC(C)CC(NC(=O)c1cc2ccccc2s1)C(=O)NC1CCN(CCc2ccc(OC3CCNC3)c(Br)c2)C1 +Cn1nccc1Cc1cnc2c(c1)cc(C(=O)NCc1ccc(Cl)cc1)c(=O)n2CC(=O)N1CC(C)(C)C1 +Cc1cccc2cc(C=CC(=O)c3ccc(I)s3)c(Cl)nc12 +COc1ccnc(Nc2ccc(Cl)c(OCc3ccccc3)c2)n1 +COc1cccc(N2CCN(CCCCNC(=O)c3ccccn3)CC2)n1 +N#Cc1cnc(NC(=O)Nc2ccc(CCNCc3ccccc3Cl)c(Cl)c2)cn1 +Fc1ccc(Cl)cc1C(F)(F)C1CCN(c2nc3cnccc3nc2NC2CC2)CC1 +O=C(NO)c1cc2ccc(NS(=O)(=O)Cc3ccccc3)cc2s1 +CCC(C)C(NC(=O)OCc1ccccc1)C(=O)NC(C=O)CC(C)C +O=C(O)CC(Cc1cc(OCCc2ccc3c(n2)NCCC3)n(CC(=O)O)n1)c1ccc2c(c1)OCO2 +O=C(NO)C1CCS(=O)(=O)N1Cc1ccc(-c2ccccc2)cc1 +COc1ccc2c(c1)CCCC2NC(=O)CCCN1CCN(c2ccccc2OC)CC1 +CC(=Cc1ccc(C(=O)O)cc1)c1ccc(O)c(C2(C)CCCCC2)c1 +NCCCCN1C(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +S=C1Nc2c(oc3ncccc23)C(c2cccc(OCc3cccnc3)c2)N1 +O=C(CCC(=O)N1CCN(C2CCCCCC2)CC1)c1ccc(Cl)cc1 +Cc1ccc(NC(=O)c2ccc(CN3C(=O)C=CC3=O)cc2)cc1Nc1nccc(-c2cccnc2)n1 +CC(=NOC(c1ccc(OCc2nc3ccccc3n2C)cc1)C1CCCCC1)C(=O)O +O=c1[nH]c2c(F)cccc2n1C1CCN(C2CCN(Cc3ccccc3C(F)(F)F)CC2)CC1 +CC(C)CC(CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NC(C(N)=O)C(C)C +Cc1ccc(N(C(=O)OCC2CCC(COCC(=O)O)CC2)c2ccccc2)s1 +COCc1ncc(Cc2ccc3cccc(NS(N)(=O)=O)c3n2)c2cc(OC)c(OC)cc12 +CC(C)C(NC(=O)CCC(=O)OCc1ccccc1)C(=O)NC(CC(=O)O)C(=O)CF +N#Cc1ccc(-c2ccncc2)c(OCCc2ccccc2)c1 +CC(C)ON(CC(=O)NO)S(=O)(=O)c1ccc(Oc2ccccc2)cc1 +CN1C(=O)C(N2CCn3cc(Cc4ccccc4)nc3C2=O)COc2ccccc21 +CC(C)CN(NC(=O)OC(C)(C)C)c1ccnc(C#N)n1 +O=c1cc(Cn2c(C3CCCC3)nc3nccnc32)c2ccc(F)c(F)c2[nH]1 +CCCc1ccc(S(=O)(=O)N2CCc3cc(O)ccc3C2c2ccc(OCCN3CCCC3)cc2)cc1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2cc(OCC3CC3)ccc12 +C[S+]([O-])c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1NC1CCC(N)CC1 +CC(CN1CC(C)(C)c2cc(F)ccc21)NC(=O)OC(CC1CCCCC1)C(=O)N1CCCCC1 +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc(O)cc4)CC3)c2c1 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+O=C(NCC1Cc2ccccc2CN1C(=S)NCC1CCCN1Cc1ccsc1)Nc1ccccc1 +COc1ccc(S(=O)(=O)Oc2ccccc2NC(=O)c2ccncc2)cc1 +COc1cccc(C(=O)N2CCN(C(=O)c3ccc(-c4ccc(C)nc4)cc3)CC2)c1 +O=c1[nH]c(Cc2ccccc2-c2cc(C(F)(F)F)ccn2)nc2c1cnn2C1CCOCC1 +Nc1cnc2ccn(S(=O)(=O)c3c(Cl)nc4sccn34)c2c1 +CC1(C)CCc2c([nH]c3cc(Cl)ccc3c2=O)C1 +CCC(C)C(NC(=O)C(CC1CCCCC1)NC(=O)c1ccno1)C(=O)NCc1cccc(C(=O)N2CCC(CN)CC2)c1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(NC3CCCC3)cc2n1Cc1ccccn1 +CC(O)CCC(=O)N(c1ccc(-c2ccccc2-c2nn[nH]n2)cc1)C(C(=O)O)C(C)C +Cc1c(-c2ccccn2)nc2cc(F)ccc2c1N1CC(C)(C)c2ncc(-c3ncnc4nc[nH]c34)cc21 +COc1ccc(CNC(=O)N2C(C)CN(Cc3ccccc3)c3cnccc3C2C)cc1 +Cc1nc[nH]c1-c1c2c(=O)n(C)c(=O)n(CC3CC3)c2nn1Cc1ccnc2ccc(Cl)cc12 +CCN(CC)C(=O)N1CCN(C(=O)N2C(=O)C(CCCN=C(N)N)C2C(=O)O)CC1 +CC1C(=O)C(C)(C)Nc2ccc3c(c21)C(=Cc1ccccc1)Oc1ccccc1-3 +Cc1ccc(-c2c(-c3ccc(S(N)(=O)=O)cc3)[nH]c3ccccc23)cc1C +O=C(CC1(C2COC3CCCC3N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC(CO)CC1 +COc1ccc(C2(C(=O)OCCCN3CCC(c4ccccc4)CC3)CCCC2)cc1 +CN1C(C(=O)O)CSC1c1csc(-c2ccc(N)cc2O)n1 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+CCCCc1c(C(=O)NCc2cncn2C)cnn1-c1ncc(C)c(-c2cccs2)n1 +N#CCN1CCN(c2ccc(C(F)(F)F)cc2)c2ccc(-c3cccc(C(O)CO)n3)cc2C1 +Cc1ccccc1C(=O)Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1 +O=S(=O)(c1cccc2ccccc12)N1Cc2ccccc2N(Cc2c[nH]cn2)C(CCc2ccccc2)C1 +NC(Cc1ccc(C(=O)NCCc2ccc(-c3ccccc3)cc2)cc1)C(=O)N1Cc2ccccc2CC1C(=O)O +CCCN1CCC2c3cc4cc(Cl)ccc4nc3C(CC)C3CCCC1C23 +CCCCCc1oc(N)nc1-c1ccc(P(=O)(O)O)o1 +Cc1cc(Nc2ncc(-c3nc(-c4ccccc4)cs3)c(NC3CC(CO)C(O)C3O)n2)ccn1 +NCc1cccc(C2CCN(C(=O)c3cn(S(=O)(=O)c4ccccc4)c4ccccc34)CC2)c1 +N#Cc1c(-c2cccc(NC(=O)CCN)c2)cc(-c2ccc(F)cc2O)nc1NC(=O)c1cccs1 +COc1cc(-c2cccc3[nH]c(-c4n[nH]c5ccccc45)nc23)cc(OC)c1OC +O=C(Nc1nc2cc(Cl)ccc2[nH]1)c1ccc2cc3n(c2c1)CCCNC3=O +COc1ccc(OC)c(Sc2ccc(NC3=NCCN3)cc2)c1 +CC(CS)C(=O)N1CC(NC(=O)C(CS)Cc2ccccc2)CC1C(=O)O +Cc1c(O)ccc2c1OC(c1ccc(OCCN3CCCCC3)cc1)C(c1ccc(O)cc1)S2 +CC(C)Cn1cc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1OCCN1CCCC1 +Cc1cc(C)c(C=C2C(=O)Nc3cc(F)ccc32)[nH]1 +CCCn1c(=O)c2nc(-c3cnn(Cc4ccccc4C)c3)[nH]c2n(CCC)c1=O 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+CN(CCCCCNc1ccc(-c2ccccc2)nn1)Cc1ccccc1 +Fc1ccc(CNc2ncnc3c2cnn3CC(Cl)c2ccc(Br)cc2)cc1 +COC(C)CCOC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +CN(C)CCN1C(=O)c2cccc3c2c(cc2cccc(O)c23)C1=O +Fc1cccc(CNC2=NC(c3ccccc3)C(c3ccccc3)N2)c1 +CC(C)Nc1nc(-c2ccc(S(=O)(=O)CCN3CCCC3)cc2)cc2ncn(C)c(=O)c12 +COc1cc(CC=Cc2ccccc2C=CC(=O)O)ccc1OCC[n+]1c(C)cc(C=CC=Cc2ccc(N(C)C)cc2)cc1C +CC(C)(CO)NC(=O)c1ccc(NC2CC2)c(OCC2CC2)n1 +Cc1ccc(-c2cccc(C=CC(=O)Nc3ccc(C[N+]4(C)CCCCC4)cc3)c2)cc1 +Cc1cc(COc2ccc3c(c2)CN(CC2(c4ccc(F)cc4)NC(=O)NC2=O)C3=O)c2ccccc2n1 +O=C1Cc2c(cccc2N2CCN(Cc3ccccc3)CC2)N1 +CC(N=C(S)NCc1ccc(C(C)(C)C)cc1)c1ccc([N+](=O)[O-])cc1 +CN1CCN(c2ccc(NC(=O)c3ccc(C#N)o3)c(N3CCCC(F)C3)c2)CC1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4ccc(C#N)cc4)CC3)CN(C)C1C2 +COc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(C)c4nnc(C)n4c2)C3=O)c(OC)n1 +CNC(=O)c1c(C(N)=O)nn2c1CCOc1ccc(C#CC(C)(O)c3cc(C)on3)cc1-2 +Cc1c(C2CC2)nc2ccc(-n3ccc(OCc4ccc(C(C)C)cc4)cc3=O)cn12 +Nc1nc(N)c2c(OCc3cc4ccccc4cn3)cccc2n1 +O=C1CCc2cc(C(c3ccccc3)n3ccnc3)cc3c2N1CC3 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3ccc(N)nc3)nc21 +O=S(=O)(NCCCCC(CCCc1cccnc1)CCC1N=NN=N1)c1ccc(Cl)cc1 +COC1(C#CC(O)(c2cccs2)c2cccs2)CN2CCC1CC2 +O=C(O)c1ccc(Nc2nc3c(-c4cnn(C5CCCC5)c4)cccn3n2)cc1 +O=P(O)(O)C(F)(F)c1ccc(C(F)(F)P(=O)(O)O)cc1 +Cc1cc(N=S2(=O)CCC2)cc2ncnc(Nc3ccc(Cl)cc3OC(C)C(=O)NC(C)C#N)c12 +CNC(=O)c1ccc(-c2nccnc2C2CN(c3ncc4ccccc4n3)C2)cc1F +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCN(S(C)(=O)=O)CC3)cc12 +Nc1nnc(CC(=O)NN=Cc2cccc(OCCOc3ccccc3)c2)s1 +CC1Oc2ccc(CN3CCC(N(C)C)CC3)cc2NC1=O +CC(C)n1cc(C#N)c2cc(-c3ncc(C(=O)O)s3)ccc21 +Cc1noc(C)c1S(=O)(=O)N(CCCC(F)(F)F)C1CCC(C(N)Cc2cc(F)ccc2F)CC1 +O=C(C1CCCCO1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +COC(=O)c1cc2cc(S(C)(=O)=O)ccc2n1Cc1ccc(Cl)cc1 +O=C(c1ccc(COc2ccccc2)cc1)c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12 +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NC(CO)C(=O)O +CCN1C(=O)C(=Cc2cc(-c3ccccc3)n(-c3ccc(Cl)cc3)c2-c2ccccc2)C(=O)N(CC)C1=S +CCC(=O)NCC(C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(C)c12 +O=C(O)c1cc2ccn(Cc3cccc(Cl)c3F)c2cn1 +Nc1cccc2c1CC(O)C(N1CCC(C(=O)c3ccc(Br)s3)CC1)C2 +COc1cc(C=CC(=O)c2cccc(NC(=O)c3cccs3)c2)ccc1O +CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(=O)c3ccccc3)cc12 +CCCN(CCC)C1=CC(=O)C(C(C)(C)C)=CC1=O +COc1ccccc1CCCCN1CCN(Cc2cc3ccccc3o2)CC1 +Clc1ccc2c(NC3CCCCC3Nc3ccnc4cc(Cl)ccc34)ccnc2c1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc(Oc3cccc4[nH]c(=O)[nH]c34)c2)cc1 +CNC(=O)c1cccc(S(=O)(=O)c2ccccc2Cc2c3c(n(CC(=O)O)c2C)CCNC3=O)c1 +NC1CCN(c2cncc(-c3n[nH]c4ccc(-c5c(F)cccc5F)cc34)n2)CC1 +COc1ccc(CCNCC(O)COc2ccc(O)c(NS(C)(=O)=O)c2)cc1 +CC(O)CNc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1 +Cn1cc(C#N)c2ccc(Nc3ncc(-c4ccccc4)o3)cc21 +CC(C)(C)C(=O)OCC1(CO)CC(=Cc2ccc(F)c(Br)c2)C(=O)O1 +CNC(C)C(=O)NC1CCCC2CC3CCN(CCc4ccc(Cl)cc4)CC3N2C1=O +COc1cc(COc2cnc(N)nc2N)ccc1OCCCc1ccccc1 +Clc1cccc2[nH]c3c(c12)CCc1c[nH]nc1-3 +COc1ccccc1S(=O)(=O)c1c[nH]c2cccc(OCC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)c12 +COc1cc(F)ccc1Oc1cc(Cl)ccc1C(=O)Nc1cc[nH]c(=O)c1 +C=CCN1C2CCC1C1CCC2N1C(c1ccc(C(=O)N(CC)CC)cc1)c1cccc(O)c1 +O=C(Nc1ccc(C(=O)N2CCCc3c[nH]c4cccc2c34)c(Cl)c1)c1ccccc1-c1ccccc1 +O=c1cc(N2CCCCC2)oc2c(-c3ccc(-c4ccccc4)s3)cccc12 +Cc1cc(C)c(Oc2cc(NC3CCN(Cc4ccccc4F)CC3)nc3ncnn23)c(C)c1 +Cc1cccc(C)c1N=C1SC(CC(=O)Nc2c(C)cccc2C)C(=O)N1CCc1ccccn1 +NC1CCCCC1NC(=O)c1cn2c(ccc3c(C(F)(F)F)cc(C(F)(F)F)nc32)n1 +COc1ccc(-c2cc(C#N)ccc2C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C)cn1 +COc1ccc(Nc2nnc(SCC3CCCCC3)[nH]2)cc1 +COCC1CCCN1S(=O)(=O)c1ccc2c(c1)C(=O)C(=O)N2Cc1cn(-c2ccc(C(F)(F)F)cc2)nn1 +O=C(NO)c1cnc(NCc2ccccc2-c2ccccc2)nc1 +COc1ccc(C2(c3cncnc3)NC(=N)N(C3CCOCC3)C2=O)cc1 +CNc1nc(C)c(-c2ccnc(Nc3cccc(O)c3)n2)s1 +Cn1cc(-c2ccc(-c3cncc4ccc(N5CCNC5=O)nc34)cc2)cn1 +CC(=O)N1CC(O)CC1CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +CN1CCN(c2nc(NCCCc3ccccc3)nc(NCCc3ccc(O)cc3)n2)CC1 +CCCCC#Cc1nc(NCc2cccc(I)c2)c2ncn(C3SCC(O)C3O)c2n1 +COc1cc(-c2nnc3n2CCCC3c2ccc(Cl)c(C(F)(F)F)c2)ccc1-c1cnc(C)o1 +COC(=O)c1ccc(Br)c(CSc2nc3ccccc3n2CC(=O)O)c1 +CCCNc1cc(NC(=O)c2cccnc2)cc(C(F)(F)F)c1 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+CCCCCCCCCCCCCCCCCCNC(=O)OCCSCCOC(=O)N(Cc1cccc[n+]1CC)C(C)=O +Cc1[nH]n(-c2ccccn2)c(=O)c1-c1ccc(C(F)(F)F)cc1 +N#CCc1ccc(Oc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)cc1 +CN(C)Cc1ccc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc2n1 +CCC(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cn1 +CN(C)CCCNc1cc(-c2cccc(C(F)(F)F)c2)c(C#N)c2nc3ccccc3n12 +COc1cccc(C2CN(c3nc(-c4ccncn4)cc(=O)n3C)CCO2)c1 +Cn1cnc2cc(-c3ccc(N4CCC(O)C4)c(S(C)(=O)=O)c3)nc(NC3CC3)c2c1=O +Cc1ccc(-c2c(C)c(C(=O)Nc3cccc(C)n3)nn2C)cc1 +CC1(C)CNc2cc(O)c(C(=O)N3Cc4ccccc4C3)cc21 +Cc1nc(CCO)c(-c2cc(C(=O)N3CC(c4ccc(C#N)cc4)C3)ccc2C)[nH]1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C(=O)O +N#Cc1ccccc1S(=O)(=O)NC1CCC(Nc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)CC1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]nc(OC)c3c2)c1F +Cc1nc(C)c(-c2csc(Nc3ccc(C(=O)N4C5CCC4CC(CO)C5)cn3)n2)s1 +O=C(NCCCCCCCCn1cc(-c2cccnc2)nn1)c1ccccc1-c1ccccc1 +O=c1[nH]ccn1-c1cccc(OC2c3ccccc3CC2N2CCCC2)c1 +CC(C)N1CCC(Oc2ccc(N3CCN(C(=O)c4ccc(F)cc4)CC3=O)cc2)CC1 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+C=CC1CN(CCF)C(=O)C2CCCC1N2S(=O)(=O)c1cc(Cl)cc(Cl)c1 +O=C(NCc1nc(Nc2cc(C3CC3)n[nH]2)c2cccn2n1)c1ccc(F)nc1 +Clc1ccccc1Oc1cncc(C2=CC3CNCC(C2)C3)c1 +O=c1[nH]c(CN2CCC(O)CC2)nc2c1sc1ccc(Cl)cc12 +O=C(c1ccc(O)cc1O)N(Cc1ccccc1)c1ccccc1 +O=C1NCCc2[nH]c(-c3ccnc(Nc4ccccc4)n3)cc21 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(N4CCOCC4)nc23)N1 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCC(O)CC +Cc1cc(C(F)(F)F)nc(N2C(=O)CSC2c2c(Br)cccc2Br)n1 +O=C(CCCN1CCN(CCC2CCc3ccccc3C2=O)CC1)c1ccc(F)cc1 +O=C(O)CC(O)(CC(O)CCCCCCc1ccc(Cl)cc1Cl)C(=O)O +CC12CCC3c4ccc(CBr)cc4CCC3C1CC(Cc1cccc(C(N)=O)c1)C2O +Cn1cc(C2CCC(Oc3nccnc3-c3cncnc3)CC2)c2ncccc21 +COC(c1ccc(C(=O)NCCCCCCC(=O)NO)cc1)(c1cccc(F)c1)c1cccc(F)c1 +Cc1ccc(-c2noc(C3CC(N)C3)n2)cc1NC(=O)c1cnc2ccccn12 +Nc1nc(N2CC3CC2CN3)c2sc3ccc(Br)cc3c2n1 +Cc1nc(-c2cc3cc(-c4ccnc(C(=O)NCc5ccncc5)c4)ccc3[nH]2)no1 +O=C(NCCCCCC(=O)N1Cc2ccccc2CC1C(=O)N1CCCC1)OCc1ccccc1 +CCC(CC)OC1C=C(C(=O)O)CC(NCC=Cc2ccccc2)C1NC(C)=O +CCN(CC)CC(=O)N1c2ccccc2CCc2ccc(NC(=O)OC(C)C)cc21 +O=C1CCc2c(Oc3ccc4c(c3)C3C(O4)C3c3nc4c(Cl)cc(C(F)(F)F)cc4[nH]3)ccnc2N1 +Cc1c(C(C)C)c(=O)on1C(=O)N1CCCC(CO)C1 +CS(=O)(=O)c1cccc(Nc2nccc(N(CCO)c3c(Cl)ccc4c3OCO4)n2)c1 +Cc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1 +N#CC(Cc1ccc(-c2csc(C(N)=O)c2)cc1F)NC(=O)C12CCC(CC1)CN2 +CS(=O)(=O)Cc1cccc(Nc2cc(Oc3ccc(NC(=O)C4(C(=O)Nc5ccc(F)cc5)CC4)cc3F)ncn2)c1 +Cn1ccc(S(=O)(=O)N2CCC(N3CC(CC#N)(n4cc(-c5ncnc6[nH]ccc56)cn4)C3)CC2)n1 +FC(F)COc1ccc(C(F)(F)F)cc1-c1cccn2nc(Nc3ccc4c(c3)CCNCC4)nc12 +CC(NC(=O)C1CC1)c1ccc(OC2CCN(c3ccnc(N4CCOCC4)n3)C2)cc1 +CCS(=O)(=O)c1ccc(OC)c(-c2ccc(C(C)N3CCCC3)[nH]2)c1 +CCNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)nc3c2C(=O)N(C2CCN(C)CC2)CC(C)(C)O3)cc1 +CC(O)(c1ccc(C(=O)N(C2CC2)C2CCC(C#N)(c3ccccc3)CC2)cc1)C(F)(F)F +CCCOc1c(NC(=O)N(O)CC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC +Cn1c(=O)cnn(CCCCN2CCN(c3ccccc3OCCF)CC2)c1=O +Fc1cc(-c2ccccc2)cc(-n2nnc(-c3ccccn3)n2)c1 +COc1ccc(-c2nc(N3CCOCC3)c3sc(CN(C)c4ncc(C(=O)NO)cn4)cc3n2)cn1 +CCCCN(C)C(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1C 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+CCc1cc(CCc2nc3cccc(C)c3o2)c(O)nc1C +Nc1c(C(=O)c2cc3ccccc3[nH]2)cnn1-c1ccc2[nH]c(C(F)(F)F)nc2c1 +CCNc1nc2ccccc2n1-c1nc2c(c(C(C)(C)S(C)(=O)=O)n1)OCC1COCCN21 +CC(C)=CCN(Cc1ccc2ncn(C)c(=O)c2c1)c1ccc(C(=O)NCc2cccnc2)cc1 +Cn1c2c(c3ccccc31)CN(CCCC(=O)c1ccc(F)cc1)CC2 +NC(=O)n1cc(NC(=O)N2CC(F)CC2CNS(=O)(=O)c2ccccc2)c2ccccc21 +CC(C)n1nc(-c2cnc3[nH]cc(C(F)(F)F)c3c2)cc1C1CN(C2COC2)C1 +Cc1ccc(-n2nc(-c3ccc(NS(=O)(=O)c4cccc(N(C)C)c4)cc3)cc2N)cc1 +COc1cccc(CNCC(C)n2c(=O)c(-c3cccc(OC)c3)c(C)n(Cc3c(F)cccc3F)c2=O)c1 +COc1ccc(-c2cnn(C3CCN(CC(=O)NCc4nc5c(c(=O)[nH]4)COCC5)CC3)c2)cc1 +O=C(c1ccccc1)N1CCC(c2ccccc2)(c2nccn2Cc2ccccc2)CC1 +C=C(CN(C)C)C(=O)c1ccc(OS(=O)(=O)c2ccc(C(=O)O)cc2)cc1 +Cc1cc(C2CCN(S(=O)(=O)C(C)(C)C(=O)NO)CC2)ccc1-c1cccc(OCCN(C)C)c1 +Cc1cc(-c2nc(-c3ccc(F)c(OCC4(C)COC4)c3)n3c2CCOC(C)C3)cc(C)n1 +O=C(NCCF)Nc1ccc(-c2nc(C3=CCOCC3)c3cnn(CC(F)(F)F)c3n2)cc1 +Nc1n[nH]c2c1c(Nc1ccc(C(=O)O)cc1)nc1ccccc12 +COc1ccccc1-c1cc2nnc(Nc3ccc(S(=O)(=O)NCCN4CCCC4)cc3)nc2cc1C +O=C(CC(Nc1ccc([N+](=O)[O-])cc1)c1cccc(F)c1)c1ccccc1 +COc1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1OC +COc1cccc(-c2c(Cc3ccc(C=CC(=O)O)cc3)c3ccc(O)cc3oc2=O)c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1ccc(C(=O)Nc2ccccc2)cc1 +OC1CCN(Cc2cccc(I)c2)CC1N1CCC2(C=Cc3ccccc32)CC1 +NC(=O)C(c1ccccc1F)N1CCCC(NC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)C1 +COc1ccc2[nH]cc(CCCN3CCN(CCCc4c[nH]c5ccc(OC)cc45)CC3)c2c1 +NS(=O)(=O)c1ccc(Nc2nc(Cl)nc(Nc3ccccc3)n2)cc1 +NCCCN1N=C(C=Cc2ccc(O)cc2)c2ccccc2N(Cc2ccc(-c3ccccc3)cc2)C1=O +COc1cc(-c2cnc(N)c(-c3ccc(C(N)=O)cc3)c2)ccc1O +Cc1c(C2CCN(C)CC2)[nH]c(-c2ccc(F)cc2)c1-c1ccncc1 +O=C(CCN(CCC1c2ccccc2-c2ccccc21)CC1CC1)N1CCN(c2ccc([N+](=O)[O-])cc2)CC1 +Cn1ccc(-c2ccc(Nc3nn(C4(CC#N)CCN(C(=O)OC(C)(C)C)CC4)cc3C(N)=O)cc2)n1 +COc1c(OCC(C)(C)O)ncnc1N1CCC(Oc2ccc(C(C)NC(C)=O)cc2)C1 +CC1=C(C(=O)N2CCN(c3ccc(F)cc3)CC2)C(c2ccc(Cl)cc2Cl)n2nccc2N1 +NC(=O)c1cccc(Oc2nc(-c3cccc4[nH]ncc34)nc(N3CCOCC3)n2)c1 +Cc1cc(COc2ccc(S(=O)(=O)CC3(CC(=O)NO)CCN(C)C3)cc2)c2ccccc2n1 +CC(C)NC(C)c1nc2c(C(N)=O)cccc2[nH]1 +O=C(NCC(NS(=O)(=O)c1cccs1)C(=O)O)c1ccc2c(c1)C(=O)N(CCC1CCNCC1)C2 +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CC(=O)O)CC(O)CC1O +Cc1ccccc1-n1[nH]c2cc(=O)n(Cc3ccccn3)c(C)c2c1=O +O=C(CCCCCNC(=O)NC(=O)c1cccc([N+](=O)[O-])c1)NO +CCCNc1ncc2c(n1)c(Nc1ccccc1)nc1cc(C(=O)O)ccc12 +NCc1ccc(NC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)nc1 +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(Nc2ccc(CCC(=O)NCCCN3CCN(C)CC3)cc2)n1 +Cc1c(Nc2c(C#N)cncc2C=Cc2ccc(S(=O)(=O)N(C(C)C)C(C)C)cc2)ccc2[nH]ccc12 +CC(=O)NC1CCC2(C)C(CCC3C4CC=C(c5cccnc5)C4(C)CCC32)C1 +CC(=O)N(C1=C(Cl)C(=O)c2ccccc2C1=O)c1ccc(C(=O)O)cc1 +c1ccc(N2CCN(CCC3CCC(c4c[nH]c5ccccc45)CC3)CC2)cc1 +O=C(O)c1ccc2c(c1)nc(Nc1ccccc1)c1nc(NCCCN3CCOCC3)ncc12 +COc1ccc(S(=O)(=O)N2CCOCC2)cc1-c1ccc(CN2CCCCCC2c2ccccc2)[nH]1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(C#N)cc3)c2)c2cnccc21 +CCCn1c(=O)c2nc(-c3cccn3C)[nH]c2n(CCC)c1=O +O=C(Nc1ncnc2[nH]cnc12)c1ccc(-c2ccc(-n3cccc3)cc2)cc1 +Fc1cccc(-c2c[nH]c3ncnc(N4CCOCC4)c23)c1F +Cc1cc(Cl)ccc1C1=CC(C)(C)Oc2cc(NS(C)(=O)=O)ccc21 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+CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C1NC=C(CCc2ccccc2)S1 +CN(C)c1ccc(C(=O)Oc2ccc3nc(S(N)(=O)=O)sc3c2)cc1 +CN(C)C1CN(C(=O)C(COCc2ccccc2)NC(=O)c2cccnc2Oc2ccc(C(F)(F)F)cc2Cl)C1 +N#Cc1c(Cl)cccc1S(=O)(=O)Nc1ccc(-c2ccc3c(N)n[nH]c3c2)cc1 +Cc1cc(-c2nc(C3CC3)no2)cc(Oc2ccc3c(c2)N(S(=O)(=O)c2ccc(Cl)cc2)CCC3)n1 +O=C(OCCCCCCCCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1)c1cc(O)c(O)c(O)c1 +CS(=O)(=O)c1ccc2c(c1)c1c(n2Cc2ccc(Cl)cc2)C(CC(=O)O)CC1 +COc1ccc(CCCCOc2ccc(CSc3c(Cl)cccc3Cl)nc2C=CC(=O)O)cc1 +CCc1ncc(Cc2ccc3cccc(O)c3n2)c2cc(OC)c(OC)cc12 +COc1ncc(-c2ccc3nc(NC(=O)NCCN4CCCCC4)sc3c2)cc1NS(=O)(=O)c1ccc(F)cc1 +O=C(O)c1ccc(CN(CCCCc2ccccc2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 +O=C(Nc1ccc(Cl)c(Nc2nccc(-c3cccnc3)n2)c1)c1ccccc1 +Cc1ccc(S(=O)(=O)NC(Cc2cccc(C(=N)N)c2)C(=O)N2CCN(C(=O)NCCc3ccccc3)CC2)cc1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c4c(ccc3nc2-1)OCCN4CC#N +CC(C)(C)N1CCC(Oc2cc(-c3ccc(F)cc3F)c3ccc(=O)n(-c4c(Cl)cccc4Cl)c3c2)CC1 +COc1cc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)ccc1F 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+O=C(NC1CCCCN(Cc2ccccn2)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +COc1c(F)cc(CNc2c3c(nc4ccc(C#N)cc24)CCN(C(C)=O)C3)cc1Cl +CCN1Cc2ccc(NC(=O)C(F)(F)F)cc2-c2ccccc21 +COC(=O)C1(c2ccccc2)CCN(CCCCCN2C(C)=NC(C)=C(C(N)=O)C2c2ccc(F)cc2F)CC1 +COC(=O)C1CCCN1C(=O)c1cccc(C(=O)N2CCCC2C(=O)N2CCCC2)c1 +O=C(c1cccnc1)n1nc(NC2CCN(Cc3ccc4c(c3)OCO4)CC2)c2cc(Cl)ccc21 +CC(C)C(NC(=O)OCc1ccccc1)C(=O)N1CCCCN1C#N +CC(C)c1ccc(-c2ccc3c4[nH]ncc4c(=O)n(CC(F)(F)F)c3c2)c(Cl)n1 +Cn1ccc(-c2cc3c(-c4cccc(-n5ccc6cc(C7CC7)cc(F)c6c5=O)c4CO)ccnc3[nH]2)n1 +CCOC(=O)c1cn2ncnc(Nc3cccc(C(=O)NOC)c3)c2c1C(C)C +N=C(N)c1ccc2oc(CCCCCCCCCCCc3cc4cc(C(=N)N)ccc4o3)cc2c1 +CCc1cc(NCc2ccc3c(-c4nnn[nH]4)cc4ccccc4c(=O)c3c2)n2nccc2n1 +CCN(CC)c1ccc2nc3c4ccccc4c(=O)cc-3oc2c1 +CC(=O)N1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccc(N5CCN(C(C)=O)CC5)cc4)n3)cc2)CC1 +Cc1cc(-c2cccc(NC(=O)N(CCC(c3ccccc3)c3ccccc3)CCN3CCOCC3)c2)on1 +Nc1ccc(CCCCN2C3CCC2CC(OC(c2ccc(F)cc2)c2ccc(F)cc2)C3)cc1 +O=C(Nc1ccccc1)Nc1ccsc1-c1nc(O)c(O)c(C(=O)O)n1 +O=C(c1ccc2c(c1)ncn2-c1ccc(Cl)cc1)N1CCCCC1 +CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCC34CC5CC(CC(C5)C3)C4)cc2C1=[N+](C)[O-] +Cc1cnn(CCOc2cc(Cl)cc(Cl)c2-c2nc(N)nc3c2CN(C(=O)NC24CC(C2)C4)C3)c1 +CC1=C(C)C(=O)C(C(CCCCC(=O)O)c2cccnc2)=C(C)C1=O +CC1(C)OOC2(CCC(C(=O)Nc3ccc4ncnc(Nc5cccc(Cl)c5)c4c3)CC2)OO1 +CCC(CC)CN1CCC(S(=O)(=O)CCCOc2ccc3[nH]c4nc(O)nc-4cc3c2)CC1 +O=C1CC(CN2CCC(c3noc4cc(F)ccc34)CC2)Cc2[nH]ncc21 +CCS(=O)(=O)CCOC12CCCCC1(S(=O)(=O)c1ccc(Cl)cc1)c1c(F)ccc(F)c1OC2 +Cc1cc2nc(NC(=O)N3CCN(C(=O)c4cccc(F)c4)CC3)sc2cc1C +Cc1cc(C(O)c2ccccc2Br)nc(Nc2ccc(C#N)cc2)n1 +Cc1ccc(N(C(=O)NCCCN2CCC3(CCc4ccccc43)CC2)c2ccc(F)c(F)c2)cc1 +CCN(CC)C(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)Cc3c(C)noc3C)cc2F)CC1 +CC(C)S(=O)(=O)c1c(Cl)ccc(Nc2nc(=O)cc(C3CC3)[nH]2)c1O +CN(C)C=NC(=O)c1cnn2c1n[n+]([O-])c1ccc(OCc3ccncc3)cc12 +CCOC(=O)c1cc2cnc(Nc3ccc(N4CCNCC4)cn3)nc2n(C2CCCC2)c1=O +O=C(Nc1nc(-c2ccccc2)cs1)c1ccc([N+](=O)[O-])cc1 +CN1CCC(C(=O)N2Cc3c(NC(=O)c4cccc(F)c4)n[nH]c3C2(C)C)CC1 +Cc1cc(-n2cc(C(F)(F)F)cn2)ccc1C(Nc1ccc(C(=O)NCCC(=O)O)cn1)C1CCCCC1 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+CCCOC(=O)C=CC(=O)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 +O=C(C1CN(S(=O)(=O)c2cccc3cnccc23)C1)N1CCN(c2ccnc(Cl)c2)CC1 +O=C(O)c1ccc2c(c1)nc(Oc1cccc(Cl)c1)c1ccncc12 +COc1cc(-c2nnc3n(C(C)c4ccc(F)cc4)cc(C(C)(F)F)cc2-3)ccc1-n1cnc(C)c1 +CC1(c2nc(NC(=O)c3ncc(F)cc3N)ccc2F)N=C(N)OCC1(F)F +CCOC(=O)CC1CC(n2cc(-c3ccccc3)c3c(N)ncnc32)CN1 +Cc1cc(C)cc(-c2cc(-c3ccc(F)cc3)c(C=CC3CC(O)CC(=O)O3)c(C(C)C)n2)c1 +Cc1cc(Nc2nccc(OCCO)n2)cc(-c2cnc(C3(O)CCC(C(N)=O)C(C)(C)C3)s2)c1 +CC1CCCN1c1ccc(C(=O)N2CCC(F)(F)C(=CC(=O)NCc3ccccn3)c3ccccc32)c(Cl)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCCC4CC4)c3)C2)cc1 +CCn1cc2cc(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)ccc2n1 +CSC1OC(c2ccc(Cl)c(Cc3ccc(OCCCC(=O)NC(C)(C)CO)cc3)c2)C(O)C(O)C1O +O=C(c1ccc(Cn2ccc3cc(Cl)ccc32)cc1)N1CCC(N2CCCC2)C1 +CN1CCN(Cc2ccc(NC(=O)Nc3ccc(-c4nc(N5CCOCC5)nc(N5C6CCC5COC6)n4)cc3)cc2)CC1 +COc1ccc2nc(C(F)(F)F)nc(NN3C(=O)C=C(C)C3=O)c2c1 +CCc1cc2c(C(=O)c3cc(Br)c(O)c(Br)c3)c(OC)ccc2o1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2C(=O)c2cccc(Cl)c2)cc1 +CCN(Cc1cc(C(F)(F)F)ccc1-c1nn(CC(=O)O)c2cccc(F)c12)C(=O)C1CC1 +O=c1[nH]c2c(O)ccc(C(O)CNCCCSCCCOCCc3ccccc3)c2s1 +O=c1n(-c2ccccc2)nc2c(NC3CCCCC3)nc3ncccc3n12 +Fc1cccc(COc2ccc(Nc3ncnc4ccc(-c5ccc(CN6CCNCC6)o5)cc34)cc2Cl)c1 +CCCCCCCCCCCOc1ccccc1CCC(=O)OCCCOP(=O)(O)OCC(N)C(=O)O +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccc(F)cc1Cl)CC2 +C=C(C)n1c(=O)n(CCN2CCC(N(C(=O)CC)c3cccc(Cl)c3)CC2)c2ccccc21 +O=C1CCC2CN(CC3CC3)CCC2(c2cccc(O)c2)C1 +CC(C)(C)c1ccc(C(=O)Nc2[nH]nc3c2CN(C(=O)Cc2ccsc2)C3)cc1 +CCc1c(Sc2cc(OC)ccc2OC)[nH]c2nc(N)nc(N)c12 +CC(C)(C)OC(=O)NC(CO)C(=O)N1CC2(CC1C(=O)NCCCCCC(=O)NO)SCCS2 +OC1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCOC5)c4n3)nc2)C1 +COc1ccc(CSc2nc(C(=O)c3ccccc3F)c(C(C)C)c(=O)[nH]2)cc1 +Oc1ccc2[nH]c3c(c2c1)CCN(CCCCc1ccccc1)C3 +CCCN(c1ccccc1Cl)S(=O)(=O)c1ccc(O)c(C)c1 +C=CC(=O)Nc1cccc(CNc2nc(Nc3cnn(CCN4CCOCC4)c3)ncc2Cl)c1 +CC(c1ccncc1)N1CCN(S(=O)(=O)c2ccc(C(C)(C)C)cc2)C(C)C1 +O=C(Cc1ccc(O)cc1)NN=C1C(=O)Nc2cccc(-c3cccc(F)c3)c21 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+CCCCCCCCn1cc(CN(C)C(C)C)c2cc(-c3cccc(C)c3)ccc21 +CC(C)CC(NC(=O)N1CCOCC1)C(=O)NC(C=O)CCc1ccccc1 +COC(=O)c1ccc(-c2ccc(CN3CCc4cc(OC)c(OC)cc4C3)cc2)cc1NC(=O)c1ccc2ccccc2n1 +COc1ccc(Cc2nnc(NC(=O)c3ccc(C4CCC(CC(=O)O)CC4)cc3)s2)cc1 +O=C(Cc1cc(Br)cc(Br)c1OC(=O)c1ccccc1Cl)NC1CCOC1=O +CCN(CC)c1ccc(Nc2cc(N(CCCN(C)C)C(=O)Nc3c(C)cccc3Cl)ncn2)cc1 +CCC(NC(=O)c1cc(C(=O)N2CCCC2CC)n2c1COCC2)c1ccc(C(F)(F)F)nc1 +COc1ccc(NC(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)NO)cc1 +O=C1NC(=O)c2c1c(-c1ccsc1)cc1[nH]c3ccc(O)cc3c21 +CC(C)[S+]([O-])c1sc2nc(-c3cccs3)cc(-c3ccccc3)c2c1N +Cc1cc([Se]Cc2sc(-c3ccc(C(F)(F)F)cc3)nc2C)ccc1OC(C)C(=O)O +Cc1noc(C)c1Cn1cc(N2C(=O)N(CCO)C(C)(C)C2=O)cn1 +COCCN=c1c(O)c(O)c1=NC(Cc1ccc(NC(=O)c2c(Cl)cncc2Cl)cc1)C(=O)O +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2ccc(Cl)c(Cl)c2)cc1 +COc1ccc(C=CC(=O)c2ccc(Cl)cc2Cl)c(OC)c1 +c1ccc(-c2nc3c(cnc4ccccc43)[nH]2)cc1 +CC1=CCCC2(C)OC2C(O)C2CCC(C)C(C)(CC1)C2COC(=O)N(C)C +CC1CN(CC(Cc2ccccc2)C(=O)NC(CCc2ccccc2)C(=O)O)CCC1(C)c1cccc(O)c1 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3cc(F)c(N)c(-c4ccoc4)c3)C2O)c1 +CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C(C)O +O=C(OCC12CCN(CC1)CC2)c1c[nH]c2ccc(F)c(Cl)c12 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCN(C(=O)OCC2CC2(F)F)CC1 +COC(=O)C1(c2cccc(Oc3ccc(C)cc3)c2)CC1C(=O)NO +CC(=O)NC1C(NC(=N)N)C=C(C(=O)NC(CCC(=O)O)C(=O)O)OC1C(O)C(O)CO +CN1CCC(N2Cc3cccc(C(N)=O)c3C2=O)CC1 +CCCCCCCCS(=O)(=O)C(C)(Cc1ccccc1)C(=O)NO +CCNC(=O)Nc1nc2ccc(-c3cccc(C#N)c3)cc2[nH]1 +COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OC +O=C(O)CCc1ccccc1CC1C2CCC(O2)C1c1nc(C(=O)NCCc2ccc(Cl)cc2)co1 +O=C(Cc1ccccc1)NC(=S)Nc1ccc(Oc2ccnc3cc(-c4nncs4)sc23)c(F)c1 +CC(C)(COc1ccc(-c2cnc(-c3ncc(C(F)(F)F)[nH]3)c(F)c2)cn1)C(=O)O +COc1ccc(S(=O)(=O)Nc2cc(-c3ccc4nc(NC(C)=O)sc4c3)cnc2Cl)cc1 +Oc1cccc(OCC(O)CNC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)c1 +c1ncc(-c2cc3c(cn2)[nH]c2ncc(-c4ccc(CN5CCCCC5)cc4)cc23)cn1 +CC1=NC(C)=C(C(=O)OCCN2C(=O)c3ccccc3S2(=O)=O)C(c2ccccc2Cl)C1=C(O)OC(C)(C)C +Cn1cnc(-c2ccc3c(c2)c(C2CCN(CCn4c(=O)[nH]c5ccccc5c4=O)CC2)cn3-c2ccc(F)cc2)n1 +CC(C)C(NS(=O)(=O)c1ccc(-c2ccc(OCCF)cc2)cc1)P(=O)(O)O +CCCCCC1=NN(C(=O)NCC2CCC3CC2C3(C)C)CC1c1ccccc1 +Cc1[nH]c(C2Cc3c([nH]c4ccccc34)C(C3CCOCC3)N2)nc1-c1ccccc1 +Nc1ccc(-c2ccc3ncc4ccc(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 +CNC(=O)C=C1COc2cc(OS(=O)(=O)c3ccc(Cl)s3)ccc21 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1noc(-c2ccccc2OC)n1 +Cc1cc(CN(CC2CCC(C(=O)O)CC2)C(C)c2ccc(Cl)c(Cl)c2)ccc1OCCN1C(=O)CCC1=O +Cc1ccc(C2=C(c3nnn[nH]3)C(=O)NC(C)(c3ccc(C)cc3)C2)cc1 +COc1ccc(-c2ccn(-c3ccc(O)c([N+](=O)[O-])c3)c2-c2ccc(C(N)=O)cc2C)cc1 +CCCCN(CC(=O)O)C(=O)C(CCCN=C(N)N)NS(=O)(=O)c1ccc2oc3ccccc3c2c1 +NCc1cccc(C2CCN(C(=O)c3ccc(C#Cc4ccccc4F)o3)CC2)c1 +Cc1cncc(-c2cc3c(cn2)cnn3-c2cccc(N3CCC(N)CC3)n2)n1 +CN1Cc2c(C3=CC4CCCC(C3)N4CC(=O)O)[nH]c3nccc(c23)-c2cc(F)ccc21 +Oc1ccc2c(c1)OCC1c3cc4c(cc3OC21)OCO4 +CC(C)N1CCC(COc2ccc(NC(=O)Nc3cccnc3Oc3ccccc3C(C)(C)C)c(F)c2)CC1 +O=C(O)c1cnc(Sc2nnc(Sc3ncc(C(=O)O)s3)s2)s1 +CCC(C)c1ccc(Oc2ccccc2S(=O)(=O)NC(C=O)C(=O)O)cc1C +Cn1nccc1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCC1 +CN(C)c1ccc(-c2nc(C(F)(F)F)cn2-c2ccc(S(C)(=O)=O)cc2)cc1Cl +O=C(c1ccccc1)C(Cc1ccc(C(F)(F)P(=O)(O)O)c(Br)c1)c1ccccc1 +CCS(=O)(=O)c1ncn2c1Cn1ncnc1-c1cc(Cl)ccc1-2 +COc1cc(C2c3cc4c(cc3C(n3cc(C(=O)Nc5ccccc5Cl)nn3)C3COC(=O)C23)OCO4)cc(OC)c1OC +Cn1cc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccc(Cl)c(Cl)c2)C(N)CC3)cn1 +CC(c1ccccc1)C(C(=O)O)C(Cc1ccccc1)C(=O)O +CC(=O)NC(C)c1ccc(OC2CCN(c3cccc(N(C)CC(F)F)n3)C2)cc1 +Cc1cc(COc2ccc(S(=O)(=O)NC3CN(C=O)CCC3C(=O)NO)cc2)c2ccccc2n1 +O=c1c(N(Cc2ccccc2)S(=O)(=O)c2ccc(Oc3ccccc3)cc2)cccn1O +COc1c(OCC2CC(F)(F)C2)ccc2c1CCN(Cc1ccc(C(C)NC(=O)C3CC3)cc1)C2 +CN(C)Cc1ccc2ccc(Cl)c(C3=C(c4cn(C)c5ccccc45)C(=O)NC3=O)c2c1 +Cc1nc2c(N3CCOCC3)ncnc2n1Cc1ccc(-c2ccncc2)cc1 +CNC(C)C(=O)NC(C(=O)NC1CC2CCC1N(CCc1ccccc1)C2)C1CCCCC1 +O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1NC(=O)c1scc(CN2CCSCC2)c1Cl +Cc1cnc2[nH]cc(Cc3cnc(NCc4ccc(C(F)(F)F)nc4)c(F)c3)c2c1 +O=C(NC1CCCCC1)N1N=C(c2ccc(Br)cc2)CC1c1ccc(F)cc1 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+COc1ccc2[nH]c3c(N4CCN(CCc5ccc(F)c(F)c5)CC4)ncnc3c2c1[N+](=O)[O-] +CC(C)OC(=O)c1c(O)cc(OCCN2CCOCC2)cc1CCCN1C(=O)C=CC1=O +COC1C=CC=C(C)C(=O)Nc2ccc(O)c(c2)CC(C)CC(OC)C(O)C(C)C=C(C)C1OC(N)=O +Cc1cc(C)c(Sc2cn(C)c(=O)c(Nc3ccc(C#N)cc3)n2)c(C)c1 +O=C1NC(=O)C(c2ccc(Oc3ccc(Br)cc3)cc2)(N2CCN(c3ccc(I)cc3)CC2)C(=O)N1 +CCc1ccc(CN2CCC(N3Cc4cccc(C(N)=O)c4C3=O)CC2)cc1 +COc1cccc2c(C(=O)NCc3cccc(COc4ccccc4F)n3)nc(N)nc12 +COc1ccc2nc(C)cc(N3CCC(NC(=S)Nc4ccc(Cl)cc4)CC3)c2c1 +O=C(c1ccccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1)N1CCOCC1 +CCNc1nc(C2CC(C)CN2C(=O)C(O)C(O)C(=O)NC(C)c2ccc(-n3cccn3)cc2)cs1 +Cc1ccc(-c2noc(C3CC4(C3)OCCO4)n2)cc1NC(=O)c1cnc2ccccn12 +Cc1ccc(C)c(CNc2nc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +COc1cc(C=CC(=O)OCCc2cccc(O)c2)ccc1O +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccnc(C(F)(F)F)c3)cn2CCN2CCC2)CC1 +Nc1ccc(-c2cccs2)cc1NC(=O)c1cnc2c(C3CC3)c(N3CCNCC3)ccc2c1 +Cc1ccc2cc(-c3n[nH]c4cccnc34)[nH]c2c1 +N#CCOc1cccc(C#Cc2ccc(CCC(=O)O)cc2)c1 +Cc1cccc2cc(Cn3nc(C#CC(C)O)c4c(N)ncnc43)n(-c3ccccc3O)c(=O)c12 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+Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(Cn5ncc6cnccc65)C4)cc23)ccn1 +Cc1cccc2nc(Cn3cnc4ccccc43)cc(=O)n12 +Cc1n[nH]cc1-c1cc2nc(CN3CCC(F)C3)[nH]c(=O)c2s1 +COc1ccc(C(C)C)cc1C1COCC2(C1)OCCNC2c1ccc(F)cc1 +N#Cc1cc(F)cc(S(=O)(=O)c2cnc3cc(Cl)ccc3c2N2CCC(CO)CC2)c1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)nn2C)cc1Nc1ncnc2cnc(N(C)CC3CCCCO3)nc12 +CCCCCCCCNC(=O)N(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)c1c(F)cc(F)cc1F +NC(C(=O)N1CCCC1)C1CCC(NS(=O)(=O)c2ccc(C(=O)O)cc2)C1 +N#CCNC(=O)Cc1nnc(Cc2nc3c(Br)cccc3s2)o1 +Cc1cc(C(F)(F)C(F)(F)F)ccc1NC(=O)c1cccc(I)c1C(=O)NC(C)C +CN(C)c1ccc2c(c1)OC(N)=C(C#N)C2c1ccc(N(C)C)c2ccccc12 +COc1ccccc1Cc1sc(NCc2ccc3c(c2)CCO3)nc1-c1ccc(Cl)cc1Cl +CCN(C)CC(=O)c1ccc(OC2Cc3cc(OC)c(OC)cc3C2=O)cc1 +CNc1ccc2c(c1)C(C#CC(C)C)(C(F)(F)F)OC(=O)N2 +N#Cc1ccc(-c2cc(NCC(O)c3ccccc3)ncn2)cc1 +CCS(=O)(=O)NC1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)CC1 +CC(C)CC(N)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CN)CC1 +NC1=NCC(Cc2cccc(C(F)(F)F)c2)C(N)=N1 +Cc1ccc(C(=O)C(=O)c2ccccc2)cc1[N+](=O)[O-] +CCS(=N)(=O)c1ccc(Nc2ncc(Br)c(NC(COC)C(C)O)n2)cc1 +Cc1ccc(-c2cnc(N(CCOc3ccccc3)Cc3ccc(C(=O)NO)cc3)s2)cc1 +Clc1ccc(C(c2ccc(Cl)cc2)(c2cc[nH]n2)n2ccnc2)cc1 +O=C(Nc1ccc(-c2ccncc2)c(-c2ccncc2)n1)C1CC1 +CN1CC2(CCN(C(=O)Nc3cc(F)cc(F)c3)CC2)C1c1ccc(Cl)cc1 +CC(CNC(=O)c1cccn2c(=O)c3cc4ccccc4cc3nc12)N(C)C +O=C(NCC1CCCCN1)C1C(C(=O)Nc2ncc(Br)s2)C2CCC1C21CC1 +CCCOC(=O)N1CCc2c(OCCc3nc(-c4ccccc4)oc3C)ccc(CCC(=O)O)c2C1 +O=C(Nc1sc2c(c1C(=O)N1CCOCC1)CCOC2)c1c(Cl)cccc1Cl +Cc1cccc(C)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccncc4)c3c2)CC(F)(F)C1 +CCCCC(NC(=O)N1CCOCC1)C(=O)NC(C#N)CCc1ccccc1 +NCCCCCC(=O)N1CCN(c2nc(N3CCOCC3)nc(-n3c(C(F)F)nc4ccccc43)n2)CC1 +CSc1cccc(N(C)C(=N)Nc2cc([S+](C)[O-])ccc2Cl)c1 +Cc1cc(-c2cn3ncc(C(N)=O)c(NC4CN(C(=O)C5(C#N)CC5)CC4C)c3n2)ccn1 +CCCN(CCC)C(=O)c1c(CC)c(N2CCN(C)CC2)nc2ccccc12 +CCN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(C(F)(F)F)cc2)[nH]c2ccccc12 +CN(C)CCc1ccc(Nc2ncc3c(n2)N2CCC(=O)N2C(c2c(Cl)cccc2Cl)=C3)cc1 +COc1ccccc1C1CN(c2nc(-c3ccncc3)cc(=O)n2C)CCN1 +Nc1ccc(C(=O)OC2COC3C(OC(=O)NCc4ccccc4)COC23)cc1 +N#CCCNC(=O)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cccc(F)c3)o2)c1 +COc1cccc(CNCCCNc2ccnc3cc(Oc4cccc(N(C)C)c4)ccc23)c1O +O=C(Nc1ccc(C(=O)NCCN2CCCC2)cc1)Nc1ccc(C(F)(F)F)cc1 +c1ccc2c(c1)Cn1nc(Cc3nc4c(s3)CCCC4)nc1-2 +COc1cc(Nc2c(C#N)cnc3cc(C=Cc4cccnc4)ccc23)c(Cl)cc1Cl +O=C1c2ccccc2C(=O)N1CCCCN1CCN2c3ccccc3Cc3ccccc3C2C1 +O=C(Nc1ccc([N+](=O)[O-])cc1)OCCN1C(=O)c2ccccc2C1=O +CC(O)C(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1c(F)cccc1F +O=C(OCC1CCCC(c2cc(F)cc(F)c2)N1S(=O)(=O)c1ccc(Cl)cc1)N1CCC(N2CCCCC2)CC1 +CC(C)(C)c1cc(NC(=O)Nc2ccccc2)n(-c2ccccc2)n1 +CCCc1c(N2CCN(C)CC2)nc2ccccc2c1C(=O)OCC +CCOC(=O)CCC(=O)c1ccc(-c2cc3ncn(C)c(=O)c3c(N3CCC(CO)C3)n2)cc1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(C(O)c2ccc(Cl)cc2)CC1 +CCc1nnc(SCC(=O)Nc2ccc(C)cc2Br)n1-c1ccc(C)cc1 +C=C(C)Cn1ccc2c(Oc3ccc(N(C)C)cc3)ncnc21 +NCCCCn1c(SCCc2c[nH]c3ccccc23)nnc1-c1ccc2ccccc2n1 +COc1cc(-c2nc3ccc(Cl)cn3c2NC2CCCCC2)ccc1OCCCNC(=O)Nc1ccc(C(F)(F)F)cc1 +CCN(CC)CCCCCC(=O)Nc1ccc(C(=O)Nc2nccs2)cc1 +CN1CCN(c2ccc3c(C(=O)NCC(c4cnc(C(F)(F)F)nc4)N4CCC(F)(F)CC4)c(Cl)ccc3n2)CC1 +O=c1[nH]c(=O)n(C(CCc2ccc(OCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)cc2)c2ccccc2)o1 +Cc1ccc(Nc2ncnc3cc(OC(C)C)c4c(c23)OCCO4)cc1[N+](=O)[O-] +Cc1cc(CNc2nccc(Nc3cc(CCc4ccccc4)[nH]n3)n2)on1 +C=C(C)C(CC)CN1CCC(CNC(=O)c2ccc3cc(Cl)ccc3c2)NC(CCN2CCCCC2)C1=O +CCOC(=O)N1CCC(CN2CCC(N3C(=O)Cc4ccccc43)C2)CC1 +CCOC(=O)C1CCN(C(=O)C(Cc2c[nH]c3ccccc23)NC(=O)Nc2ccc(Br)cc2)CC1 +O=C1C2CCCN2C(=O)N1CCCN1CCN(c2cccc(Cl)c2)CC1 +NS(=O)(=O)c1ccc(CN2S(=O)(=O)c3ccccc3S2(=O)=O)cc1 +COc1cccc(-n2nnc(-c3ccccc3NC(=O)Nc3ccc(NC(=O)CBr)cc3)n2)c1 +COc1cc(C(=O)NC2CCN(C)CC2OC)c(C)cc1Nc1ncc(Cl)c(Oc2cccc3c2C(=O)N(C)C3)n1 +CCC(NC(=O)c1cc(C(=O)NC(CC)c2ccc(F)cc2)n2c1C(C)OCC2)c1ccccc1 +O=C(c1ccccc1)c1sc(NCc2cccs2)nc1-c1ccco1 +OC1(c2ccc(Cl)c(C(F)(F)F)c2)CCN(C2Cc3ccccc3C2)CC1 +O=S1(=O)NCc2ccccc2N1C1CCN(C2CCCCCCC2)CC1 +NC1=NC2(CCO1)c1cc(NC(=O)c3ccc(Cl)cn3)ccc1Oc1c2cc(C2=CCCOC2)nc1F 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+O=C(NC(CNC(=O)c1ccc2nn(CCCNC3=NCCN3)cc2c1)C(=O)O)OCc1ccccc1 +Fc1cc(-c2nccnc2Oc2ccc(Nc3ccccn3)cc2)ccn1 +CSCCC(NC(=O)CNC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O +CCCc1ccc(-c2ccc(N(CC3(N)CCOCC3)C(=O)C3CC3c3ccccn3)cc2)cc1 +C=Cc1ccc(C(=O)NCCN2CCC(n3c(=O)[nH]c4ccccc43)CC2)cc1 +CC(Oc1cc(F)ccc1Nc1ncnc2cc(N=S3(=O)CCC3)cc(F)c12)C(=O)NC(C)C(F)(F)F +Cc1c(CN(C)c2ccccc2Cl)cnc2nc(N)nc(N)c12 +O=C(c1cc(-c2[nH]ncc2-c2cccc(Cl)c2)c[nH]1)N1CCOCC1 +Nc1nccc(-c2ccc3nc(C4COc5ccccc5C4)oc3c2)n1 +Cn1cc(F)cc(C2CCCN2c2ccn3ncc(C(=O)NC(CO)C(C)(C)C)c3n2)c1=O +COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)CC2C)ccc1Cl +CN(C)N1C(CCc2ccccc2)CCCC1CCc1ccccc1 +CC1c2ncn(-c3ccc(F)cc3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1F +CON=C1CCC(CNc2cc(F)c(S(=O)(=O)Nc3nccs3)cc2Cl)CC1 +CCN(CC)CCNCCC(=O)Nc1ccc(Nc2nc(-c3ccccc3NC(=O)CCNCCN(CC)CC)nc3ccccc23)cc1 +CC(N)Cc1c2c(c(COCC(=O)Oc3ccccc3)c3c1OCC3)OCC2 +COC(=O)C1C2CCC(CC1c1ccc(C)c(F)c1)N2 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(CN3CCCC3=O)c12 +CC(C)CC(NC(=O)C(NC(=O)c1ccc(-c2ccccc2)cc1)C(C)O)B(O)O 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+CC1Cc2c(OCc3cc(-c4ccccc4)ccn3)ccc3c2c(c(CC(C)(C)C(=O)O)n3Cc2ccc(Cl)cc2)S1 +CC(=O)c1ccc2[nH]c(C(=O)N3CC4CC45C3=CC(=O)c3ccccc35)cc2c1 +CCCOc1ccc(C=CC(=O)Nc2ccc(NC(=O)Cc3ccc(C)cc3)c(C(=O)c3ccccc3)c2)cc1 +Fc1ccc2nc(-c3cccc(-c4cn5ccccc5n4)c3)[nH]c2c1 +O=C1CN(c2ccc(CO)cc2)CCN1CC(O)CN1CCc2ccccc2C1 +COc1ccc(CCNCC(O)COC(=O)c2cccc(F)c2)cc1OC +CCNC(=O)C1OC(n2cnc3c(N)nc(C#CCCCC#N)nc32)C(O)C1O +CC(C)CN(c1cccc(F)c1)S(=O)(=O)c1ccc(OC2CCN(S(C)(=O)=O)CC2)cc1 +COc1ccc2nc(NC(c3ccccc3O)P(=O)(OC)OC)sc2c1 +Cc1cccc(CC(NC(=O)c2ccc(F)cc2F)C(=O)NCC#N)c1 +CC1(C)CC(=O)c2c(SC(C)(C)C)sc(-c3cc[nH]n3)c2C1 +CCCC(C)=CC1CC2C=CC(C)C(CCC3CC(O)CC(=O)O3)C2C(OC(=O)C(C)(C)CC)C1 +Cc1ccc(C(=O)NN2C(=O)C(=Cc3cccn3C)SC2=S)cc1 +O=C(NN=C(c1ccccc1)c1ccccc1)Nc1ccncc1 +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc(CN4CCOCC4)c4onc(N)c34)cc2)c1 +O=C(O)c1nc(Cc2cc(Cl)ccc2OCc2ccccc2)cs1 +CS(=O)(=O)c1ccc2ccn(C3OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C3O)c(=O)c2c1 +COc1ccc(Nc2ncnc3ccc4nc(C(N)=O)sc4c23)cc1 +COCCOc1cc2ncnc(Nc3ccc(F)c(C#N)c3)c2c2c1OCCO2 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+CCOC(=O)c1c(-c2cccc(-c3ccccc3)c2)[nH]c2cc(OC)ccc2c1=O +CNCc1cc(C#CCCN2CCSCC2)ccc1Oc1ccc(Cl)c(Cl)c1 +NC(=O)c1cccc2c(NC(CCO)c3cccc(NC(=O)C4CC4(F)F)c3)ncnc12 +NCC1CCCCN1C(=O)C1CCC2CN1C(=O)N2OS(=O)(=O)O +O=C(NCc1ccc(OC(F)(F)F)cc1)C1c2cccc(F)c2C(=O)N1CCc1ccccn1 +CCCCCCCCCCCCCCCCCC(=O)c1n[nH]c2c1C(=O)N(c1ccc(Cl)cc1)C2=O +CCc1cccc(Nc2cc(NC3CCCCC3N)nnc2C(N)=O)n1 +CC(=O)OC1C=CC(=O)OC1C(COC(=O)C=Cc1ccccc1)OC(C)=O +C=CS(=O)(=O)c1cc2c(Nc3cccc(Br)c3)ncnc2cn1 +Cc1cc(CN(C)C)ccc1C(=O)Cn1ccc(OCc2ccc(Cl)cn2)cc1=O +Cc1nc(N)nc(-c2c(Nc3cc[nH]n3)nc3ccc(-c4cncn4C)cn23)n1 +CC(NC1CCCNC1)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)CC2NCCc3ccccc32)CC1 +CN(C)c1ccccc1C(=O)N1CCN(C(=O)C(=O)c2c[nH]c3ccccc23)CC1 +COC12CCC3(CC1CNC(=O)C(CC(C)C)NC(C)=O)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +O=C(c1nnc(C2CCN(Cc3ccc(F)cc3)CC2)o1)c1nc2ccc(-c3ccccc3)cc2s1 +CC(C)N(C)CC#CCCC(=O)C(O)(c1ccccc1)C1CCCCC1 +COc1ccc(C(=O)Nc2ncc(-c3ccc(C(=O)O)cc3OCc3ccccc3Cl)s2)cc1 +CC1=C(C(=O)OC2CCCC2)C(c2ccc(Cl)cc2)C2=C(CC(c3ccc(Cl)cc3)CC2=O)N1 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+N=C(N)NCCCC(NC(=O)C1CCCN1C(=O)C(CC1CCCCC1)NCC(=O)O)C(=O)c1nc2ccccc2s1 +CC1CC(Nc2n[nH]c3cc(NC(=O)NC(C)c4ccccc4)ncc23)C(C)O1 +CCNC(=O)C1OC(n2cnc3c(Nc4ccc(OCC(=O)Nc5ccc6c(c5)OCO6)cc4)ncnc32)C(O)C1O +CC1(C)CC(=O)c2c(NCCO)sc(-c3cc[nH]n3)c2C1 +CC(C)c1[nH]c(=O)c(-c2csc(-c3ccncc3)n2)cc1C(=O)OCCN1CCCC1 +CN(c1ccc([N+](=O)[O-])cc1OCc1ccc([N+](=O)[O-])cc1)S(C)(=O)=O +ClC(Cn1ncc2c(Nc3ccccc3)nc(SCCN3CCOCC3)nc21)c1ccccc1 +CCCc1nn(C)c2c(=O)[nH]c(-c3cc(S(=O)(=O)NCCCCCO)ccc3OCC)nc12 +O=C(NC1CC(C(=O)O)Nc2cc(Cl)cc(Cl)c21)C1CCCCC1 +CCOC(=O)c1cccc(Nc2ncc3cc(-c4c(Cl)cccc4Cl)c(=O)n(C)c3n2)c1 +CCN(C(=O)c1ccc(CNc2nc(NCCN(C)C)nc(N3CCc4ccccc4C3)n2)cc1)c1cccc(C)c1 +NC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2ncc3ccccc3c2C(F)(F)F)cc1 +Oc1ccc2c(c1)CCC1CC(O)(C#CCl)CCC21Cc1ccccc1 +O=C(O)Cc1nn(CC(=O)Nc2cc(C(F)(F)F)ccc2Br)c(=O)c2ccccc12 +CN(C)CCn1c(=O)c2ccc3sc4ccccc4c4ccc(c1=O)c2c34 +N#Cc1ccc(C2C3=C(CCC3=O)N(c3cccc(C(F)(F)F)c3)C(=O)N2C(=O)NCC2CCOC2)cc1 +COC(=O)C=Cc1cccc(N(Cc2ccc(C=CC(=O)OC(C)(C)C)cc2)C(=O)c2ccccc2)c1 +CNCCCC1Cc2ccccc2N(c2c(F)cccc2F)S1(=O)=O +Cc1ccc(C2=C(C#N)C(=O)NC(c3ccc(Oc4ccccc4)cc3)(C(F)(F)F)C2)cc1 +O=C(O)CCNc1nc(Cc2nnc(SCC(=O)NNC(=O)c3ccccc3)n2NC(=O)c2ccc(Cl)cc2)cs1 +Cc1c(C)c2c(c(Cc3cn(CCCCCC4CCSS4)nn3)c1O)CCC(C)(C)O2 +COc1cccc2cc(C(=O)NCCCN3CCN(CCCNC(=O)c4cc5cccc(OC)c5oc4=N)CC3)c(=N)oc12 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)c1ccc2cc[nH]c2c1 +COc1ccc2c(c1)-n1ncc(C(=O)OCc3ccccc3)c1NC2 +O=S(=O)(Nc1ncns1)N1CCc2c(cccc2-c2ccc(C(F)(F)F)cc2C2=CCNCC2)C1 +COc1ccc2ncc(F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCc3cccc(N)c3)[nH]c3ccc(Cl)cc23)c1 +Cc1cc(OCCCCOc2ccc(C(=O)CC(C)C)c(O)c2C)ccc1C(=O)O +Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1[N+](=O)[O-] +O=C1CC(O)CC(CCn2c(-c3ccc(F)cc3)ccc2C(F)(F)F)O1 +COc1ccc(CP(=O)(O)CC(CCC(=O)O)C(=O)O)cc1 +COc1cc(-c2cccc(C)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ncccn3)ccc21 +COc1cc(-c2cc(F)cc(Cl)c2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3cnccn3)ccc21 +COc1cc(Nc2ncc(C(O)c3ccc(Cl)cc3)s2)ccc1-n1cnc(C)c1 +CC12CCNC(=O)C=C1CCC1C2CCC2(C)C(O)CCC12 +O=C(O)Cn1c(=O)c(=O)[nH]c2cc([N+](=O)[O-])c(-n3ccc(CNCCCc4ccccc4)c3)cc21 +CCc1ccc(CNCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(=O)NC(C)(C)C)c(C)c1 +N=c1n(CC(=O)NN=Cc2ccc(F)cc2)c2ccc([N+](=O)[O-])cc2n1CC(=O)NN=Cc1ccc(F)cc1 +Cc1cc(NC(=O)N2CC=C(c3ncc(-c4nnc(CO)o4)cc3Cl)CC2)ccc1OC(F)(F)F +CN(C)CCCNC(=O)c1cc(-c2c(O)cc(O)cc2Oc2ccc([N+](=O)[O-])cc2)on1 +Cc1nc2ccccc2n1-c1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +COc1cc(-n2ccnc2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)C)n1)CCN2 +C=CCC1Oc2ccc(OCC#N)c(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +O=C(O)CC1CCC(c2ccc(-c3ccc4c(c3)OCCN4C(=O)NCc3ccccc3)cc2)CC1 +CC(Cc1ccc(C#Cc2ccc(OC3CC3)cc2)cc1)NC(=O)C1CC1 +OCC1CC(Nc2nc(NC3CC3)ncc2-c2nc3cnccc3s2)C(O)C1O +COCCNc1nccc(-c2noc3c(F)c4c(cc23)CC2(C(=O)NC(=O)NC2=O)C2C(C)OC(C)CN42)n1 +Cc1ccc(COc2c(C3CCC3)ccc(-c3cnc(N)cn3)c2F)cc1C +O=C(O)CC1CCCc2c1n(Cc1ccc(Cl)cc1)c1c(Br)cccc21 +CC(C)(C)C(=O)Nc1ccc2ccn(Cc3cccc(-c4cccc5c4OCO5)c3)c2c1 +CCn1c(C(C)NS(=O)(=O)c2ccc(Cl)cc2)nc2ccccc21 +COc1ccccc1-c1nnc2c3c(c(OCc4ccccn4)nn12)C1CCC3CC1 +COC1CCC2(CC1)Cc1ccc(-c3cncc(C#N)c3)cc1C21N=C(N)N(C(C)C)C1=O +CCCCC(Sc1cc(OCCc2ccccc2)cc(OCCc2ccccc2)c1)C(=O)O +CC(C)S(=O)(=O)N1CCC(c2ccc(CC(C#N)NC(=O)C3NC4CCC3C4)cc2)CC1 +CCCCOC(=O)Nc1ccc(Nc2ncnc3cc(OC)c(OC)cc23)cc1 +CC=C1C(C2(C)CCCC(C)(C)C2)=CCC2C(OC(C)=O)OC(OC(C)=O)C12 +COC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCC(C(=O)OC)(c3ccccc3)CC2)C1c1cccc(C)c1 +C=CCc1c(C)nc(-c2ccsc2)nc1Nc1ccc(C(=O)O)cc1 +CC(C)(C)CC1NC(C(=O)Nc2ccc(OCCO)cc2)C(c2cccc(Cl)c2F)C12C(=O)Nc1cc(Cl)ccc12 +COc1cccc(OC)c1C1CCCC(=O)N1Cc1cccc(-c2cncs2)c1 +N#Cc1cn(-c2ccc(C(=O)O)c(O)c2)c2cc(OCCO)ccc12 +CC(=O)c1ccc(Cn2nc3c(c2Nc2ccc(F)c(C)c2)C(=O)N(C)C2=NC(C)(C)CN23)cc1 +O=Cc1cn(-c2nc(-c3cc4cc(Br)cc(Br)c4oc3=O)cs2)nc1-c1ccccc1 +CC1CN(CC(=O)N2CC(C)(C)c3cnc(Cc4ccc(F)cc4F)cc32)C(CN2CCOC2=O)CN1 +CNC(=O)c1cc2ccc(CCNC(=O)Nc3cccc(S(=O)(=O)C(F)(F)F)c3)cc2cn1 +CCOc1ccccc1-c1ccc(C(=O)NC(C=Cc2ccccc2)C(Cc2cccc(C(=N)N)c2)C(=O)OC)cc1 +COc1ccccc1-c1noc(C(C)Nc2nccc(N3C(=O)OCC3C(C)C)n2)n1 +O=C(NO)c1ccc(OCCCCCCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)cc1O +COc1ccc(C=C2COc3cc(OCCCCCNc4c5c(nc6ccccc46)CCCC5)ccc3C2=O)cc1 +CC1(c2noc(NC3CCC(CNS(=O)(=O)C(C)(C)C)CC3)n2)CC(F)(F)C1 +COc1cc(Nc2cc(-c3ccccc3)on2)ccc1-c1cnco1 +NC1CN(c2ccncc2Nc2ncc3ccc(-c4c(F)cccc4F)nn23)CCC1F +COC(=O)CC1c2ccccc2N=C(Nc2ccc(-c3ccccc3)cc2)N1CCCCCNC(=O)OC(C)(C)C +CCN(CC)CCCNc1c(Cl)cccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2 +Cc1cccc(Cl)c1NC(=O)c1sc(NC(=O)c2cccs2)nc1C +Cc1cc(=O)oc2cc(OCC=CCN3CCC(c4noc5cc(F)ccc45)CC3)ccc12 +O=C(O)c1cc(-c2ccc(C=C3SC(=S)N(CCc4ccccc4)C3=O)o2)cnc1Cl +O=C(c1cccc(Nc2ncc(-c3ccc4c(c3)OCO4)cn2)c1)N1CCOCC1 +CC(C)CS(=O)(=O)NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1 +COc1cc(-c2c(-c3ccc4[nH]ccc4c3)c(=O)c2=O)cc(OC)c1OC +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc4c(c3)OC(F)(F)O4)C2)cc1 +CC(=C(F)C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1Br)c1cccc(C(=N)N)c1 +O=C1Cc2cc(Cc3ccc(-c4cccs4)cc3)ccc2C(=O)N1O +[O-][n+]1ccc(CC(c2ccc(COc3ccc(F)cc3)cc2)c2ccc(OC(F)F)c(OC(F)F)c2)cc1 +CCNc1cc(O)c2c(c1)C=CCC(OC(=O)C(F)(F)F)C(O)C(=O)C=CC(C)C(C)OC2=O +COc1ccc(-c2ccc(C(N)=O)nc2)cc1OC1CC2CCC1C2 +CC(C)n1c(=O)n(Cc2nc3ccccc3n2CCN(C)C)c2ccccc21 +O=C(Cn1c(-c2ccccc2)nc2ccccc21)Nc1ccc(Cl)cc1 +COc1ccc(-c2cc(C(=O)NC3CCCc4c3cnn4-c3ccccc3F)n(C)n2)cc1 +CCCC(CC1(C(=O)NC(CO)Cc2ccccc2)CCCC1)C(=O)O +COc1ccc(CNC(C)=O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +CCS(=O)(=O)n1cc(C(=O)OC2CC3COCC(C2)N3)c2ccccc21 +CCc1c(C#N)c(-c2ccc(-c3cccc(OC)c3)cc2)c(C(=O)O)n1C +Cc1cc(F)ccc1Nc1nc2cc(F)c(N(C)C(=O)C=CCN(C)C)cc2n2cncc12 +O=C(NC1CCC(CCN2CCC(c3noc4cc(F)ccc34)CC2)CC1)c1ccc(N2CCOCC2)nn1 +CN(C)C(=O)c1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1 +Cc1cc(Nc2cc(N3CCCCC3)nc(Sc3ccc(NC(=O)C4CCCCC4)cc3)n2)n[nH]1 +O=C(O)c1cccc(-c2cnc(C(=O)C3Cc4ccc(-c5ccccc5)cc4C3)o2)n1 +COc1ccc(S(=O)(=O)N(Cc2ccc(F)nc2)C(C(=O)NO)C(C)C)cc1 +CC1(C)CC(n2ncc(NCCN3CCOCC3)c(Cl)c2=O)CC(C)(C)C1 +CN1Cc2c(C3=CCN(C4CCC(CC(=O)O)CC4)CC3)[nH]c3nccc(c23)-c2cc(F)c(F)cc21 +O=C(Cc1cccc(OC(F)(F)F)c1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3cccc(OC(F)F)c3)s2)nn1 +Cc1ncn(-c2ccc(Nc3cc(-c4nocc4C)ccn3)cc2)n1 +COc1ccc(-c2cnn(-c3ccc(S(=O)(=O)Nc4ccc(CCNCC(O)c5cccnc5)cc4)cc3)n2)cc1F +CCC(CNc1ccc(OC(F)(F)F)cc1)NC(=O)C(CC1CCCCC1)NC(=O)N1CCOCC1 +COc1ccc(C(=O)NCc2cccc(Oc3ccc(OC(C)(C)C(=O)O)c(C)c3)c2)c(C)c1 +CC1CCN(C(=O)c2cccc(COc3c(Cl)cccc3Cl)n2)CC1 +CN(C)CCOCCn1c2ccccc2c2c3c(c4c5ccccc5[nH]c4c21)C(=O)N(CCN(C)C)C3=O +N=C(N)c1cccc(CN2CCC(NS(=O)(=O)c3cc4nc(Cl)ccc4s3)C2=O)c1 +CC(C)C(NS(=O)(=O)c1c(F)c(F)c(F)c(F)c1F)C(=O)NO +Cc1ccc(CNC(=O)Nc2cccc3[nH]ncc23)c(N2CCCCC2)n1 +CCNC(=O)c1cc(N)c(Nc2ccc(C#N)cc2)cc1Oc1c(C)cc(CCC#N)cc1C +ON=C(CCCN1CCN(c2ccccn2)CC1)c1ccc(F)cc1 +NC(=O)c1ccccc1-c1cc(F)cc(-n2nnc(-c3ccccn3)n2)c1 +C=CCN1CC(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)OC1=O +CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCN +O=C1C2=C(OC3=CC=CCC13)C([N+](=O)[O-])=CCC2 +CC(C)S(=O)(=O)NCC1CC(c2ccc(-c3ccccc3C#N)c(F)c2)=NO1 +NS(=O)(=O)c1c(F)c(F)c(Sc2nc3ccccc3s2)c(F)c1F +CCc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(=O)O)c1 +CC(c1ccc(F)c(F)c1)N1CCC2(CCC(O)CC2)OC1=O +COC1CN(C(=O)N2CCC(C)(N3CCc4c(-c5cnc(N)nc5)nc(N5CCOCC5C)nc43)C2)C1 +OCC(CN1CCN(Cc2ccccc2)CC1)OC(c1ccccc1)c1ccccc1 +COc1cc(-c2ccc3c(-c4nc5ccccc5[nH]4)n[nH]c3c2)c(CO)cc1O +NC(C(=O)O)C(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)O +O=C(O)c1cccc(Nc2cccc(S(F)(F)(F)(F)F)c2)c1 +COC12CCC3(CC1(C)C(O)c1cccc(F)c1)C1Cc4ccc(O)c5c4C3(CCN1CC1CC1)C2O5 +CC(O)(c1ccc(N(C(CF)CF)S(=O)(=O)c2ccccc2Cl)cc1)C(F)(F)F +O=C(NCc1ccccc1)OC1COC2C(OC(=O)c3cccc4ccccc34)COC12 +CC(C)(CO)NC(=O)c1cc2cc(Nc3ncc(F)c(Nc4cccc(O)c4)n3)ccc2o1 +c1cc2occc2c(NC2=NCC3(CN4CCC3CC4)O2)n1 +CCc1cc2c(cc1N1CCC(N3CCN(C)CC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CCN(CC)CCNC(=O)c1c(C)[nH]c(C=C2C(=O)Nc3ccc(-c4cnc5ccccc5n4)cc32)c1C +COc1ccc(Nc2nc(-c3ccc(C(N)=O)c(F)c3)cn3ccnc23)cc1OC +Cn1c(=O)c2nc(-c3ccccc3N)[nH]c2n(C)c1=O +CN1C(=O)C(N2CCc3cn(Cc4c(F)cccc4F)nc3C2=O)COc2cc(C#N)ccc21 +c1cc(C2CNCCO2)ccc1Nc1ncc(C2CC2)cn1 +CN(c1ccc(Cl)cc1)c1ccc(C(=O)c2ccc(C(=O)C3CC3c3ccccc3)c(C(=O)O)c2)nc1 +Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccccc2)C(N)C3)c1 +CC(C)c1ncc(CO)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +Cc1nnc(Nc2nc(N3CCN(C(=O)Cc4ccccc4)CC3)nn3cccc23)s1 +CC(=O)Nc1cccc(Cl)c1C(=O)OCN1C(=O)c2ccccc2S1(=O)=O +Cc1cccc([P+](Cc2ccc(Oc3ccccc3)cc2)(c2cccc(C)c2)c2cccc(C)c2)c1 +COCCOC1CCC2(CC1)Cc1ccc(Cl)cc1C21N=C(N)N(C)C1=O +FC1CCNCC1n1cc(-c2ccc3c(c2)Cc2c[nH]nc2-3)c(-c2ccncc2)n1 +CCOC(=O)c1cn(C)c(=O)cc1Nc1ccc(I)cc1F +O=S(=O)(c1ccc(Cl)cc1)C12CCOC(CCC(O)CO)C1COc1c(F)ccc(F)c12 +O=C(c1ccc2c(c1)-c1[nH]nc(-c3ccc(-c4ccc(O)cc4)cc3)c1C2)N1CCOCC1 +CC(C)CCNc1ccc2nnn3c4ccccc4c(=O)c1c23 +NC1(c2ccc(-c3nc4ccn5c(=O)[nH]nc5c4cc3-c3ccccc3)cc2)CCC1 +O=C(Nc1nnc(-c2cncs2)s1)C(Cc1ccccc1)NCc1cscn1 +Brc1c(Br)c(Br)c2[nH]c(NCCCn3ccnc3)nc2c1Br +CN1C(=N)NC(C)(c2sc(-c3nnc(-c4nccs4)o3)cc2Cl)CS1(=O)=O +COc1cc(-c2ccc(F)cc2F)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CS(=O)(=O)c1ccc(Nc2nccc(Oc3ccc4c(C(=O)Nc5ccccc5)cccc4c3)n2)cc1 +COc1ccc(-c2cc3c(NC4CCC(C)(N)C4(C)C)c(C(N)=O)cnn3c2)cc1 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+C=CC(=O)Nc1ccc(CNc2nc(Nc3cnn(CCOC)c3)ncc2Cl)cc1 +O=C(NCCc1nc2ccccc2[nH]1)c1ccc(Cl)c([N+](=O)[O-])c1 +CC1CCC(NC(=O)c2cc3cc(Br)cnc3n(Cc3ccc(F)cc3)c2=O)CC1 +CC(O)(C(=O)Nc1ccc(S(=O)(=O)NCCc2ccc(F)cc2)cc1Cl)C(F)(F)F +NC(=O)c1cncc(OCc2cccc(NC(=O)c3cc4ccccc4[nH]3)c2)c1 +O=C(NCC1CCC1)c1ncccc1NC(=O)c1cccc2cccnc12 +NCc1ccn2c(-c3ccnc(N)n3)c(-c3ccc(F)cc3)nc2c1 +COc1nc2cccnc2n1-c1ccc(C(=O)c2nc3ccccc3[nH]2)cc1 +Cc1ccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)s1 +CCNC(=O)C(CCc1ccccc1)NC(=O)C(NC(=O)c1ccc(OCc2ccccc2)cc1)C(C)O +CCCCN1CCN(c2ccc(S(=O)(=O)Oc3cccc(F)c3)cc2)C1=O +CC(C)CC(CC(=O)NO)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)NC(C)c1ccccc1 +COc1ccc(NC(=O)Nc2ccc(N(C)C)cc2)cc1-c1c(Br)cnn1C +O=C(O)c1ccc(-n2c(C=Cc3cccc([N+](=O)[O-])c3)nc3ccc(I)cc3c2=O)cc1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2cccc(Cl)c2)CCN(C(=O)OC(C)(C)C)CC1 +O=C(NCC1(O)CCCCCC1)c1cc(-n2ncc(=O)[nH]c2=O)ccc1Cl +COc1ccc(OC)c(Nc2nc3ccccc3nc2NS(=O)(=O)c2ccc3c(c2)sc(=O)n3C)c1 +NC(=O)c1ccc(Oc2ccc3c(c2)CN(CCc2ccccc2)C3)nc1 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+CC(C)Oc1ccc2cc(-c3nn(C(C)C)c4ncnc(N)c34)ccc2c1 +O=c1cc(C(F)(F)F)c2cc3c(cc2[nH]1)OCC1CCCCN31 +O=C(Nc1ccc(Br)cc1)C1C(C(=O)NC2CCC(CN3CCCC3)CC2)C2C=CC1C21CC1 +O=C(O)Cc1csc(-c2cc(Cl)ccc2OCc2ccccc2)n1 +O=C1C(O)c2ccccc2N1CCn1cc(COc2ccc(CNNc3ccnc4cc(Cl)ccc34)cc2)nn1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3cccc(C(N)=O)c3)NC(=O)NC1=O)C2 +CC1(C)C(C(=O)O)C1c1nc2cc(OCc3ccc4ccccc4n3)ccc2n1Cc1cccc(-c2ccc(F)cc2)c1 +COCC1OC(OCCc2ccccc2)C(NCCN)C(OCc2ccc3ccccc3c2)C1O +c1ccc(-c2nnn(-c3ccc(Oc4cccnc4)cc3)n2)nc1 +CCSC(=S)SCC(=O)c1ccc(C(=O)NCc2ccccc2)s1 +Cc1ccc(C2CC3CCC(C2c2cc(-c4ccc(F)cc4)no2)N3C)cc1 +COc1cc(C=CC(=O)NO)ccc1OCC(Cc1c[nH]c2ccccc12)NC(=O)C1CCCN1C(=O)OC(C)(C)C +CN(C)C(=O)c1ccccc1Sc1cc(N)c(Cl)cc1[N+](=O)[O-] +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)NC(C)(C)C)CC1 +COC1(C)CC(O)C2C(C)C(=O)OC2C2C1CCC2(C)O +O=C(Nc1ccc(Cl)cc1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCc1cc(Cl)ccc1-2 +FC(F)(F)c1ccc(Nc2nccc3nc(-c4ncccc4C(F)(F)F)cnc23)nc1 +COCC(C)NC1CCC(Nc2cc(-c3ccc(F)c(NCC4CCOCC4)n3)c(Cl)cn2)CC1 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+CCN1Cc2n[nH]c(=O)c3cc(F)cc4[nH]c(c2c43)C1 +Cc1ccc(OC(=O)NC2CC(C)CCC2C(C)C)cc1 +CN1C(=O)C=CC2(C)C3CCC4(C)C(CCC45CCCO5)C3CCC12 +CC1(C(=O)O)CCC(O)(c2ncc(-c3cccc(Nc4nccc(C(F)(F)F)n4)c3)s2)CC1 +O=C(NCC1CCCCC1)c1cnc(Nc2cccc(Cl)c2)cc1C(F)(F)F +COc1ccc(CSc2nnc(-c3ccc4c(c3)CCO4)o2)cc1Cl +N#CNC(=NCCCCCCOc1ccc(Cl)cc1)Nc1ccncc1 +CCN(CC)CCOC(=O)C1(c2ccc(-n3cnnn3)cc2)CCCC1 +OC(CCCN1CCN(c2ncc(F)cn2)CC1)C1CCCCC1 +O=C(CC(=O)N1CCOCC1)Nc1ccc2nc3n(c(=O)c2c1)CCCCC3 +O=C(N1CCc2ncc(C(F)(F)F)cc2C1)C12CCCC1CC(NC1CCCCCC1)C2 +CC(=O)c1ccc(Oc2ncnc3c2cnn3C2CCN(C(=O)OC(C)(C)C)CC2)cc1 +COc1cc(OC)c2nc(C(F)F)n(-c3nc(N4CCOCC4)nc(N4CCOCC4)n3)c2c1 +CNc1ccc(-c2noc(C(CCCC3CCCCC3)CC(=O)NO)n2)cn1 +O=C(c1c[nH]c2cc(Cl)ccc12)N1CCC2(CC1)c1ccccc1CS2(=O)=O +Nc1nc(N)c2cc(NCc3cccc4ccccc34)ccc2n1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC2Cc3ccccc3C2)C1c1cccc([N+](=O)[O-])c1 +CC(Nc1nccc(N2C(=O)OCC2C(C)C)n1)c1cnc(Oc2ccc(F)cc2)cn1 +CC(OC1CCCNC1c1ccccc1)c1cc(Cl)cc(Cl)c1 +CC1=C(CCCN)C2=C(C)C3(CC3)C(C)(O)C(=O)C2=C1 +COc1cccc2c1cc(CCNC(=O)C1CC1)n2-c1ccccc1 +CC(c1nc2ccccc2c(=O)n1-c1ccc(Br)cc1)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)C(C)C1 +COC(=O)C1=C(C)NC2=C(C(=O)CC(c3ccccc3Cl)C2)C1c1ccc([N+](=O)[O-])cc1 +Cc1cc(C)nc(N2CC3CCN(C(=O)c4cccc(C)c4-n4ccnn4)CC32)n1 +CCn1c(CN2C(=O)COc3cc(OC4CCN(C(C)=N)CC4)ccc32)cc2ccc(C(=N)N)cc21 +CN1CCC(O)(C#Cc2ccc3c(c2)-n2nc(C(N)=O)c(C(F)F)c2CCO3)C1=O +NNC(=O)CSc1nc2ccccc2c(=O)n1CCc1ccccn1 +CC(C)(CN(CC(=O)NC(CCCCN)B(O)O)C(=O)CCc1ccccc1)c1ccccc1 +FC(F)(F)c1ccnc(Sc2ccc3nnc(-c4cncs4)n3n2)n1 +CCN(CCCOc1cc(O)c2c(=O)c3ccccc3sc2c1)Cc1ccccc1N(C)C +CNC(=O)c1cnc(N)c2cc(-c3ccc(C)cc3)sc12 +N#Cc1ccc(Cn2cncc2CNC2C(=O)N(c3ccccc3)CCc3ccccc32)cc1 +Cn1nc(-c2ccc3c(c2)CC2CCC(C3)C23CN(CC(F)(F)F)S(=O)(=O)N3)cc1-c1ccc(Cl)c(Cl)c1 +CCOC(=O)C1CCN(C(=O)CCC(=O)N(CC(C)(C)C)c2ccc(Cl)cc2C(O)c2ccccc2Cl)CC1 +O=C(NO)c1ccc(CN2C(=O)CNC(=O)C2Cc2cccs2)cc1 +CCCCC(=O)c1cc(C(C)(C)C)c2c(c1)C(C)(C)CO2 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3c[nH]c4ccncc34)nc21 +CCc1cc(C2CC2)c(-c2nnc(OC)[nH]2)cc1C(=O)N1CCC(F)(c2ccc(C#N)cc2)CC1 +Cc1c(C)c2ccc(OCc3c(F)c(F)c(F)c(F)c3F)cc2oc1=O +COc1cccc(C(=O)NN2c3ccc(Cl)cc3N=C(N3CCN(C)CC3)c3ccccc32)c1 +CNC(=O)c1c(-c2ccc(F)cc2)oc2ccc(-c3ccc4c(n3)C(=O)N(Cc3ccc(F)cc3)CC4)cc12 +COc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3cc(Cl)ccc32)ccc1OCCN1C(=O)CSC1=O +CN1CCC2(CC1)NC(=O)c1cc(C=CC(=O)NO)ccc1O2 +COC1CCN(C(=O)C(C)Oc2cc(F)ccc2Nc2ncnc3cc(N=S(C)(C)=O)cc(C)c23)CC1 +CCCCON=C1C(=O)N2c3ccccc3C34CCN5CC6=CCOC1C(C6CC53)C24 +CCOC(=O)C1CN(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CCO1 +Cc1ccc(CC2(O)CCN(CCOc3ccc(O)cc3)CC2)cc1 +O=C(CCN1CCN(c2ncccn2)CC1)NC12CC3CC(CC(C3)C1)C2 +CCC1(C(=O)Nc2cc(N(C)C)cc(C(F)(F)F)c2)CN(c2c(C)cccc2C)C(=O)C1C +O=C(Nc1ccc(N2CCOCC2)cc1)Nc1ccc2nc(-c3ccco3)c(-c3ccco3)nc2c1 +Clc1cccc(C2CCN(CCCOc3ccc4scnc4c3)CC2)c1Cl +O=C(NC1CCN(C2CCc3cc4c(cc32)OCO4)CC1)c1cc(=O)c2cc(F)ccc2o1 +Cn1cc(-c2cc(NS(C)(=O)=O)ccc2OCc2ccccc2)c2cc[nH]c2c1=O +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(Cl)cn3)c2)c2cnccc21 +COc1ccc(C(=O)Nc2cccc(C(C)Nc3ncnc4c(C(N)=O)cc(F)cc34)c2)cc1F +Cc1nc2ccc(CN(C)c3ccc(C(=O)NC(CCC(=O)O)C(=O)O)c(N)c3)cc2c(=O)[nH]1 +CC(C)c1noc(-c2ncn3c2CN(C)C(=O)c2ccccc2-3)n1 +CCOc1ccc(C2=C(c3ccccc3)CCCc3cc(O)ccc32)cc1 +Cc1c(-c2ccc(C(C)N3CCC(CC(C)(C)O)(c4ccccc4)OC3=O)cc2)cc(=O)n(C)c1C +COCCOc1cc(OCCOC)cc(C(=O)NCCOC(=O)C2CCCCN2S(=O)(=O)Cc2ccccc2)c1 +COc1ccc2c(c1)Oc1ncn3nc(CC#N)nc3c1C2c1ccc(Cl)cc1 +Nc1nc2[nH]c(CCCc3ccc(C(=O)O)s3)cc2c(=O)[nH]1 +O=C(CCc1ccccc1)N(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)C1CCCCC1 +NS(=O)(=O)Oc1ccc(NC(=O)N2CCN(c3nccc(-c4cc5ccccc5o4)n3)CC2)cc1 +CN1CCN(C(=O)c2cc(Oc3ccc(Cl)cc3)c3c(c2)c2ccccc2n3CCCN2CCCCC2)CC1 +NCc1ccc(C(=O)Nc2ccncc2F)cc1-c1cccc(C(=O)OC2CCCOC2)c1 +COc1ccc(CC(=O)NC(NC(=NC#N)Nc2cccnc2OC)C(C)(Cl)Cl)cc1OC +Cc1cn(-c2ccc(-c3nc(Nc4cc(C(F)(F)F)ccc4F)n(C)n3)cc2OC(F)(F)F)cn1 +COc1ccc(C=CC(=O)C=Cc2ccc(OC)cc2)cc1 +CCCCCCCCCCCCCCCCN1C(=O)C(=O)c2ccccc21 +Cc1noc(C)c1CN(Cc1ccc2nc(C)n(C)c(=O)c2c1)c1ccc(C(=O)NCc2cccnc2)cc1 +N#CCc1ccc(Nc2ncnc3ccc(-c4cccc([N+](=O)[O-])c4)cc23)cc1 +C=Cc1csc(Sc2cc3c(cc2NS(C)(=O)=O)COC3=O)n1 +CC(Nc1c(Nc2ccnc(Nc3ccc(Br)cc3)n2)c(=O)c1=O)C(C)(C)C +CS(=O)(=O)NC1CCN(c2nc3ccccc3n(C3CCN(C4CCCCCCC4)CC3)c2=O)C1 +O=C(NCc1ccc[nH]1)C(=O)c1c[nH]c2ccccc12 +NCC1CCN(Cc2ccn3ncnc(Nc4ccc5c(cnn5Cc5cccc(F)c5)c4)c23)CC1 +CC1OC(OC2CCC3(C)C(CCC4C3CCC3(C)C(CCC(=O)O)CCC43O)C2)C(O)C(O)C1O +COc1ccc(-c2cccc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)n2)cc1 +COC(=O)C(CCSC)NC(=O)c1cccc(CN(Cc2ccc(C#N)cc2)Cc2cncn2Cc2ccc(C#N)cc2)c1 +Cc1ccc(Sc2cnc(Nc3ccccn3)s2)cc1C(=O)N1CCNCC1 +Cc1nccn1CCC(C(N)=O)(c1ccccc1)C1CCCCC1 +COc1ccc(C(=O)Nc2ncccn2)cc1Nc1nccc(-c2cccnc2)n1 +CCc1ccn2c(C3CCN(CC4CN(C(CC5CCC5)C(=O)O)CC4c4cccc(F)c4)CC3)cnc2c1 +COCCOc1cc2c(cc1C(=O)Nc1ccc(F)c(Cl)c1)nc(Nc1c(Cl)ccc(CNC(=O)C(C)(C)C)c1Cl)n2C +O=C1NC(=O)C(c2ccc(Oc3ccccc3)cc2)(N2CCCN(C(=O)c3c(Cl)cccc3Cl)CC2)C(=O)N1 +CCCCCOc1cc2ccccc2cc1C(O)CCCCCCC(=O)O +COC(=O)CCc1cccc(-c2nc(NCCc3ccc(F)cc3)nc(OC)n2)c1 +COC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccc(N)c(NC(=O)C(N)CCCNC(=N)N)c1 +CNC(=O)n1cc(NC(=O)N2C(C(=O)NC(CN(C)C)c3cccc(Cl)c3F)CC3CC32)c2ccccc21 +Cc1cnccc1-c1[nH]c(-c2ccc(Cl)cc2)nc1-c1ccc(F)cc1 +OC(COc1ccnc2cc(C(F)(F)F)ccc12)CN1CCN(C(c2ccccc2)c2ccccc2)CC1 +O=C(O)c1nc(-c2ccccc2)n(-c2cccc(Cl)c2)c1-c1cccc(Cl)c1 +Cc1c(Cc2c(Cl)cccc2Cl)c(=O)ccn1CCc1ccc(-c2c[nH]c(CNC(=O)Nc3ncc(Br)s3)n2)cc1 +Cn1cc2c(nc(N=C(Nc3ccc(Br)cc3)Nc3ccc(Br)cc3)n3nc(-c4ccco4)nc23)n1 +COc1ccccc1N1CCN(CCCOC(=O)CC23CC4CC(CC(C)(C4)C2)C3)CC1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(CF)(CF)Oc4ccccc43)cc21 +COc1ccc(S(=O)(=O)c2nc3ccccc3nc2Nc2ccccc2)cc1 +CC(=O)Nc1cccc(Nc2ncnc(N3CCC(c4ccccc4)CC3)n2)c1C +Cn1cc(-c2ccc3nc(NC(=O)c4csc(-c5ccncc5)n4)cn3n2)c(-c2ccc(F)cc2)n1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1Nc1cnn(CC(F)(F)F)c1 +Cn1cc(C2=C(c3c[nH]c4cc(F)ccc34)C(=O)NC2=O)c2ccccc21 +COCCNC(=O)c1c(NC(=O)c2ccccc2OC(F)(F)F)sc2c1CCC(F)(F)C2 +CC(=O)Nc1ccc(OC2OC(CO)C(O)C(O)C2O)cc1 +CN(c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1)S(=O)(=O)c1cccc(-c2ccccc2)c1 +CC1CC(O)(CC(=O)O)c2cc(Cl)c(OCc3ccccc3)cc2O1 +Cc1cnc(Nc2ccc(CN3CCN(C)CC3)cc2)nc1-c1cccc(Cl)c1 +NC(=O)Nc1cccc(-c2cnc3cc(-c4nncs4)ccn23)c1 +O=C(Cc1cccc(Br)c1)Nc1ccc(O)c(-c2cc(C(=O)O)ccn2)c1 +CC(=O)NC(C)c1ccc(OC2CCN(c3nc(N(C)CC(C)C)ncc3Cl)C2)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NCCN5CCC(F)(F)CC5)s4)nc23)N1 +CN1CCN(c2cccc(C(=O)c3cnn(-c4ccc(F)cc4)c3N)c2)CC1 +CC(C)(C)C1CCc2onc(C(=O)Nc3cnn(Cc4ccc(Cl)cc4)c3)c2C1 +Clc1ccc2c(c1)c(NC1CCN(Cc3ccc4c(c3)OCO4)CC1)nn2-c1ccccc1 +CN(Cc1ccc(Br)cc1)c1nc(NC2CC2)n2ncc(C=C3NC(=O)NC3=O)c2n1 +CN1CC(COc2ccc(S(=O)(=O)Nc3cccc(CC(=O)O)c3)cc2)Oc2ccccc21 +Cc1nc(C(=O)NC2C3CC4CC(C3)CC2C4)c(C)n1-c1ccccc1 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cccc(-c5ccncc5)c4)c3)cc2C1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1cc(Cl)c(F)cc1-c1cn[nH]c1 +CCN(CC)c1ccc(C(=O)c2cc(C#N)c3ccc4ccccc4n23)cc1 +[O-][S+](c1cc(Cl)cc(Cl)c1)c1c(O)c(-c2cccnc2)cc2ccccc12 +COC(=O)COc1cc2c(c3c1c(C(=O)C(N)=O)c(C)n3Cc1ccccc1)CCC2 +Cn1cc2c(Nc3nc(NC4CCCCC4N)nnc3C(N)=O)cccc2n1 +O=C1c2ccc(C3CC3)cc2OCCN1c1cccc(-c2ccnc3[nH]c(-c4ccc(C(O)CO)cc4)cc23)c1CO +CCCCc1nc(-c2ccc(C(=O)OC)c[n+]2[O-])cn1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1ccc(C)c2c1Sc1c(ccc3ccccc13)N2CCCN(C)C +CCN(C(=O)Cc1ccc(S(C)(=O)=O)cc1)C1CCN(CCC(c2ccccc2)c2ccc(C(N)=O)cc2)CC1 +Cc1cc(Nc2c(C)cccc2C)c2nc(N3CCOCC3)cc(=O)n2c1 +CCN(CC)Cc1cc(Nc2ccnc3cc(Cl)ccc23)cc(-c2ccc(Cl)cc2)c1F +CNCCN1CCC(c2cnc3[nH]c(-c4cccnc4OC)nc3c2)CC1 +CN1C2CCC1C(C(=O)OCCOS(=O)(=O)c1ccccc1)C(c1ccc(Br)cc1)C2 +CN(C)CC(=O)N1CCC2(CC1)C(=O)Nc1cc(C=C3c4ccccc4COc4cc(F)ccc43)ccc12 +CNC(=O)c1ccc(C)c(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)c1 +Cc1cc(Cl)nc(C)c1C(=O)NCCC(C)N1CCC(N2C(=O)N(C(C)C)CC2c2ccccc2)CC1 +Cc1cc(S(=O)(=O)NC(=O)Nc2ncc(Br)s2)sc1CC(C)C +O=C(NCc1c(Cl)cc(Cl)cc1Cl)C1COc2ncccc21 +CC(C)c1ccc(-n2cc(C(=O)c3ccc(N)cc3)nn2)cc1 +Clc1cccc(N2CCN(CCCCNc3cc(-c4ccccc4)ccn3)CC2)c1Cl +O=C(CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1)N1CCC1 +NC(CC(=O)N1CCn2c(nnc2C(F)(F)F)C1)Cc1cc(F)c(F)cc1Cl +NS(=O)(=O)c1ccc(N2C(=O)CSC2c2ccccc2Br)cc1 +Cn1c(=O)c2c(SCC(=O)NCc3ccccc3)ccnc2n(C)c1=O +Cn1cc(-c2cnc3[nH]cc(-c4cc(C5(c6ccccc6)CC5)nc(N)n4)c3c2)cn1 +CNc1cc(-c2cccnc2)ccc1S(=O)(=O)c1ccccc1 +CCCCc1nc2ccc(NC)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1ccc(-c2ccc(S(=O)(=O)c3ccccc3CC(=O)NO)cc2)cc1 +CN1CCN(C(=O)c2cc(Oc3ccc(Cl)cc3)c3c(c2)c2ccccc2n3CC2CCN(C3CC3)CC2F)CC1 +O=S(=O)(Nc1nccs1)c1ccc2c(c1)OCCC2Oc1ccc(C(F)(F)F)cc1C1=CCNCC1 +COc1cc(C2=CCCCc3c2ccc2c3c(CO)cn2C)cc(OC)c1OC +c1ccc(CC2CCN(CCCn3nnnc3-c3cccc4ccccc34)CC2)cc1 +Cc1cccc(C(=O)Nc2ccc(Cl)cc2)c1NC(=O)c1sc2ccccc2c1Cl +COc1ccc(-c2cnc3nc(N)nc(N4CCN(Cc5ccccc5F)CC4)c3n2)cc1OC +COc1ccc(Cl)cc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 +O=C(NC1CCN(Cc2ccc3c(c2)OCO3)CC1)c1cc(=O)c2ccc(OC(F)F)cc2o1 +CC(CC(C)(CS(=O)(=O)N1CCC(CCc2ccc(C(F)(F)F)cc2Cl)CC1)N(O)C=O)c1ncc(F)cn1 +COCCOCC(C)(C)NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1 +COc1cccc(C2=CC(=O)c3ccc4c(c3=N2)=CC=N4)c1 +N#Cc1ccc(C(c2ccc(C#N)cc2)n2cncn2)cc1 +CCCCN(CCSC)c1cc(C)nc2c(-c3ccc(Cl)cc3Cl)nn(C)c12 +CC#Cc1cncc(-c2ccc3c(c2)C2(COC(N)=N2)C2(CCC2)CO3)c1 +COC(=O)CCc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1 +NS(=O)(=O)Oc1ccc2c3c(c(=O)oc2c1)CCCCCCCCCCC3 +CCCOc1ccc(-n2cc(CCc3ccccc3)c3cc(CCC(=O)O)ccc32)cc1 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+Cn1cc(-c2cc3c(-c4cccc(N5CC6CC5CN6)n4)n[nH]c3cn2)cn1 +CNC(=O)C(NC(=O)C(CCc1ccccc1)CP(=O)(O)Cc1ccc(Cc2ccc(OC)cc2)cc1)C(C)(C)C +CN(Cc1cccc2c1S(=O)(=O)N=C2C1=C(O)C(C(C)(C)C)N(Cc2ccc(F)cc2)C1=O)S(N)(=O)=O +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc(C(=O)c3ccc(Cl)cc3)c2)[nH]c1=O +CCC(Nc1ncnc(N)c1C#Cc1cnccn1)c1nc2cccc(F)c2c(=O)n1-c1cc(F)cc(F)c1 +CCCc1[nH]c(=O)c(Cc2ccc3oc4ccccc4c3c2)c2cc(OC)c(OC)cc12 +CC1CCCC(N2CCC(c3c(-c4ccccc4)ccc(Cl)c3F)=CC2=O)c2cc(ccn2)-c2ccccc2NC1=O +CC(C)(C)OC(=O)n1cc(-c2cncn2C2CCCCC2)c2ccccc21 +CCC(=O)N(CCCCCCCCNC(=N)N)C1CCN(CCc2ccccc2)CC1 +CC(=O)c1cc(-c2c3c(=O)n(C)c(=O)n(CC4CC4)c3nn2Cc2ccnc3ccc(Cl)cc23)n(C)c1 +CC(=O)Nc1ccc(CCN(C)C2CCN(CCCc3c[nH]c4ccc(-n5cnnc5)cc34)CC2)cc1 +COCC1=C(C(=O)NCCCN2CCC(c3ccc(F)cc3C#N)CC2)C(c2ccc(F)c(F)c2)NC(=O)N1 +CC(=O)NCC1CN(c2ccc3c(c2)CCCc2c(-c4cc(C)on4)n[nH]c2-3)C(=O)O1 +CCC1C(=O)N(C2CCN(C3CCC4CCCc5cccc3c54)CC2)c2ccccc21 +COc1ccc(F)cc1C(C)(C)CC(O)(Cc1cc2ccc(C#N)cc2[nH]1)C(F)(F)F +O=C(CNC(=O)c1ccccc1)NN=Cc1ccc([N+](=O)[O-])s1 +O=C(NC1CCC(OCCCN2CCOCC2)CC1)NC12CC3CC(CC(C3)C1)C2 +CCNC(=O)C1OC(n2cnc3c(N)nc(C#CC(C)(O)CC(C)C)nc32)C(O)C1O +Cc1noc(C)c1-c1ccc2c(c1)C(O)(c1ccc(F)cc1)C(=O)N2 +N#Cc1ccc(-c2cnccc2NS(=O)(=O)C(F)(F)F)c2ccccc12 +c1ccc(-c2n[nH]c(C3CC3)c2-c2ccnc3ccccc23)nc1 +COc1cccc(C(=O)NC(CC(C)(C)C)C(=O)NC(CCS(C)(=O)=O)CN2CCc3cc(F)ccc32)c1 +O=C(Nc1ccccn1)c1cccc(Oc2ccc3c(c2)c(=O)ncn3Cc2c(F)cc(F)cc2F)c1C(F)(F)F +COC12C(COC(N)=O)C3=C(C(=O)C(C)=C(Nc4ccc5[nH]ccc5c4)C3=O)N1CC1NC12 +Cc1nnc(C(NC(=O)c2cc(OC(C)C(F)(F)F)c(C3CC3)cn2)C2(C)COC2)o1 +COc1cccc(CC2NCCc3c2[nH]c2ccccc32)c1 +S=C(NCCCc1cnc[nH]1)NCCCN(Cc1ccc(Cl)cc1)c1ccc(Br)cc1 +CCCn1c(=O)c2nn(-c3ccccc3)cc2c2ccccc21 +Oc1ccc2c(c1)CCCC2CCCN1CCN(C2CCCCC2)CC1 +CC(C)(C)OC(=O)N1CCN(c2ccc(C#Cc3ncnc(N)c3-c3ccc(Cl)cc3)cn2)CC1 +COc1cc(N(C)CCN(C)C)c2[nH]c(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1 +O=C(c1ccc(F)cc1)C1CCN(Cc2ccccc2I)CC1 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(Cc2ccccc2)C1 +Cc1ccccc1NC(=NC#N)N1CCN(C(=O)Cc2ccccc2)C(c2ccccc2)C1 +O=c1c2scc(-c3ccccc3)c2ncn1-c1ccc(F)cc1 +O=C(NCC1CCN(CC(c2ccccc2)c2ccccc2)C(=O)C(CCN2CCOCC2)N1)c1ccc2cc(Cl)ccc2c1 +O=C(Cc1ccc(NC(=O)c2cscn2)nc1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=C(O)CCC(=O)NC(=Cc1ccc(Oc2ccccc2I)cc1)C(=O)O +COn1cc(C2=NC(c3ccc(F)cc3)(c3ccc(F)nc3)C(C)N2)ccc1=O +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)O)cc3)[nH]c2n(CCC)c1=S +Cc1nc2ccccc2c(N2CC(C)(C)c3ccc(N4CCOCC4)cc32)c1C +O=C1c2ccccc2C(=O)N1CCCCCN1CC=C(c2c[nH]c3ccc(F)cc23)CC1 +O=C1c2cc(NCCN3CCOCC3)ccc2COc2cc(Oc3ccc(F)cc3F)ccc21 +CCC(C)N(Cc1nc2c(c(=O)[nH]1)COCC2)C(=O)CN1CCC(C(=O)c2ccc(F)cc2)CC1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O +Cc1ccc(S(=O)(=O)N=C(Sc2ccccc2)c2ccccc2)cc1 +COc1cnccc1C(=O)NCC(C)(C)CN(C1=NS(=O)(=O)c2cc(F)ccc21)c1ccccc1 +CC1CCC(Cn2c(N3CCOCC3c3ccccc3)nc3cc(C(=O)N(C)C)nc(-c4cncc(Cl)c4)c32)CC1 +CC(=O)OC1CCC2C3C=CC4=CC(=O)C=CC4(C)C3CCC12C +NC(Cc1ccc(-c2cnc(NCC3CCc4ccccc4C3)cn2)cc1)C(=O)O +C=C(Br)C(=O)Nc1ccc2[nH]c(C(=O)NCCCNc3nsc4nc5ccccc5n34)cc2c1 +O=[N+]([O-])c1cccc(Nc2nccc(-c3cnn4ncccc34)n2)c1 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+O=C(COc1ccc(SCCCCSc2nccs2)cc1)COc1ccc(C(=O)O)cc1 +Cc1cc(NCCCc2cccnc2)c2n[nH]c(=O)n2c1 +N#Cc1ccc(S(=O)(=O)N2Cc3ccccc3N(Cc3c[nH]cn3)C(CCc3ccccc3)C2)c(Cl)c1 +Nc1nc(SCCN2CCN(Cc3ccccc3Cl)CC2)nc(N)c1Cc1ccccc1Cl +CC(=O)CC(=O)NCCNc1c2c(nc3ccccc13)CCCC2 +Cc1ccccc1Sc1ccc2c(-c3c(Cl)cccc3Cl)c(=O)ncn2n1 +CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)N(Cc1scc[n+]1CC)C(C)=O)OC +CC(=O)Nc1c(C(C)=O)c(O)nc2nc(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)cc12 +COc1ccc2c(c1)Cc1c(Nc3cccc(OCC(C)C)c3)n[nH]c1-2 +CC(=O)N1CC=C(c2cccnc2OC2CN(c3nc4ccccc4s3)C2)CC1 +O=c1[nH]c2ccc(C3=NCCN3)cc2c2c1sc1ccccc12 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCCC2CCC2)cc1F +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C=C(F)C(=O)NCCN1CCCC1 +CCn1c(=O)n(-c2cccc(C(F)(F)F)c2)c2c3cc(-c4ccc(N)nc4)ccc3ncc21 +S=C(NCc1cccnc1)SCCc1nnc(-c2ccc3ccccc3n2)o1 +CCN(CC)C(=O)Oc1ccc2c(c1)OC(=Cc1ccc(OCCN3CCCC3)cc1)C2=O +CS(=O)(=O)c1ccc(C(=O)NC(=S)NCCC2CCN(Cc3ccccc3)CC2)cc1 +CCc1c(C)[nH]c(=O)c(N(C)C(C)COC)c1Cc1cc(C)cc(C)c1 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+COc1ccc2c(c1)[n+]([O-])c(C#N)c(-c1ccc(Cl)cc1)[n+]2[O-] +CC(C)Oc1cc(Nc2nc(NC(C)c3ccc(F)cc3)ncc2Cl)n[nH]1 +CC(Nc1nc(Cl)cc(N2C(=O)OCC2C(C)O)n1)c1ccc(C(C)(F)F)cc1F +COc1ccc2c(CCNC(=O)c3cc(=O)c4c(OCc5ccc(Br)cc5)cccc4o3)c[nH]c2c1 +Cc1ccc(N2CCN(C(=O)C3CN(C4CCOCC4)CC3c3ccc(Cl)cc3)CC2)c(C(N)C(C)C)c1 +CCCC(=O)Nc1ccc2c(c1)-c1ccccc1C(=O)C2=O +Nc1ccccc1NC(=O)c1ccc(CNC(=O)c2cc3ccncc3[nH]2)cc1 +CC(C)C(O)CC(O)C(CC1CCCCC1)NC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2cc(F)ccc2[nH]1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCCCC3)cc12 +CCOc1ccccc1N1CCN(CCCNC(=NC#N)c2ccccn2)CC1 +O=C(Nc1sccc1-c1nc(O)c(O)c(C(=O)O)n1)OCc1ccccc1 +O=C(O)COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2 +CC(C)(C)OC(=O)NCCCCCNC(=O)C1C(C(=O)Nc2ncc(Br)s2)C2CCC1C21CC1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cncc(-c2cccnc2O)c1 +NC(=O)c1cccc(-c2ccc3c(c2)sc2c(N)ncnc23)c1 +O=C1C(CC(F)(F)F)=CC(O)(CSc2ccncc2)N1CCNc1ccnc2cc(Cl)ccc12 +Cc1ccc(CNCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(=O)NCC2CC2)c(C)c1 +Cn1cc(-c2ccc(Cn3c(CC4(C(=O)O)CCCC4)nc4cc(OCc5ccc6ccccc6n5)ccc43)cc2)cn1 +C=C1C(=O)OC2CC3(C)CCC4(C)C(CCC5C6(C)CCC(=O)C(C)(C)C6CCC54C)C3C12 +CN1CCCN(Cc2ccc(-c3ccc(CN4CCCN(C)CC4)c(Cl)c3)cc2)CC1 +COc1ccc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)Nc2ccc(C(=O)Nc3ccc(F)cc3N)cc2)cc1 +COc1cc(-c2cc(C)c(=O)n(C)c2)ccc1CN(C)C +COc1cc(C(=O)NC2CCc3cc(OC)c(OC)c(OC)c3-c3ccc(OC)c(=O)cc32)cc(OC)c1OC +COc1ncc(C(=O)NC2(C(=O)NC3COc4cc(-c5cc(Cl)cc(F)c5-c5noc(C)n5)ccc43)CC2)cn1 +CC(C)(C)Oc1ccc2cc(NC(=O)C3CC3)ncc2c1 +CN1CCN(c2ccc(C(=O)Oc3ccccc3)cc2NC(=O)c2ccc(F)c([N+](=O)[O-])c2)CC1 +CNC(C)c1ccc(C(=O)Cn2ncc(OCc3ccc(OC)cn3)cc2=O)c(C)c1 +Cc1ccc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)NC2CCC(C)CC2)cc1 +Cc1cc(NC(C)CCC(C)C)n2nc(C)c(-c3cnc(N(C)C)cc3C)c2n1 +O=c1[nH]c(=O)n(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)cc1F +CN(C)C(=O)c1cc2cnc(Nc3ccc(C(=O)N4C5CCC4CNC5)cn3)nc2n1C1CCCC1 +CC(=O)c1ccccc1-c1ccc2[nH]c(C=Cc3ccc(C(C)(C)C)cc3)nc2c1 +N#Cc1cc2c(O)c(-c3cccc(-c4ccc(F)c(F)c4)c3)c(O)nc2cc1Cl +C#Cc1cn2c(-c3ccc(C(=O)NCC(F)F)c(C)c3)cnc2c(NCCC(F)(F)F)n1 +CC(C)n1c(=O)cc(C(=O)OC2CC3CCC(C2)N3C)c2ccccc21 +N#CC(Cc1ccc(-c2ccc(S(N)(=O)=O)cc2)cc1F)NC(=O)C1NC2CC1C1CC21 +CC1(N(Cc2ccccc2)CC(O)C(Cc2ccccc2)NC(=O)OC2COC3OCCC23)C(=O)Nc2ccccc21 +Cn1c(=O)c2nc(-c3ccccc3O)[nH]c2n(C)c1=O +CCCCCCCCC#Cc1ccc2c(c1OC)CC(CO)NC(=O)C(C(C)C)N2C +CC1NC(C)(C)COC1(O)c1cccc(-c2cccc3ccccc23)c1 +Clc1ccc(-c2cc(-c3ccncc3)c(-c3ccccc3)[nH]2)cc1 +Cn1c2ccccc2c(=O)c2c(=O)n(Cc3ccco3)c(COc3ccccc3)nc21 +COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCCc2ccccc2Cl)C(C)C)C(C)C)ccc1OC +Cc1onc(-c2ccccc2)c1COc1ccc(C#N)cn1 +c1ccc2c(NCCCCCCCCCNc3c4c(nc5ccccc35)CCCC4)ccnc2c1 +Cc1nc(-c2cn3c(n2)-c2cc(-c4ccnn4C4CCCN(C5COC5)C4)c(F)cc2OCC3)n(C(C)C)n1 +CC#CCOc1ccc(S(=O)(=O)NC(C(=O)NO)c2ccc(OCCNC)cc2)cc1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(Br)s3)CC2)nc1 +O=C(Nc1cnc2ccccc2c1)c1ccnn1CCc1ccncc1 +CC1CN(C(=O)c2ccccc2)CCN1c1nnc(-c2ccccc2)c2ncccc12 +Cc1ccc(-c2cc(Br)ccc2OCc2ccc(F)cc2F)n1-c1ccc2c(c1)C(=O)NC2=O +CC1(C)CNc2c(cccc2S(=O)(=O)NC(CCCN=C(N)N)C(=O)N2CCC(CC(F)F)CC2)C1 +NC1(c2ccc(-c3nn4ccccc4c3-c3ccccc3)cc2)CCC1 +O=c1cc(OCc2ccccc2)ccn1-c1ccc2c(cnn2CCN2CCOCC2)c1 +Fc1ccc(-c2c[nH]c(C3CCN(c4ncnc5[nH]ccc45)CC3)n2)cc1C(F)(F)F +N#Cc1ccc(-c2ccc3c(c2)C2(CCCCC2)C(=O)N3)[nH]1 +COc1ccc2c(c1)C(CCCN1CCN(c3cccc(C(F)(F)F)c3)CC1)CCC2 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1ccnc(OC(F)F)c1 +COCCCOc1nc(C(F)(F)F)ccc1CNC(=O)C(C)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1cc(NC(=O)CCc2ccc3[nH]c(-c4ccc(Cl)s4)nc3c2)ccc1N1CCOCC1=O +O=C1CC(c2cccc(-n3ccnn3)c2)=Nc2ccc(C(F)F)cc2N1 +CN(C)c1cc(Oc2ccc3c(c2)CC(NCC(O)c2ccc(Cl)nc2)CC3)cc(C(=O)O)c1 +CCOC(=O)C(O)=CC(=O)c1cn(Cc2ccc(F)cc2)c2c(OC)ccc(OC)c12 +O=S(=O)(NCC1CCC(CNC2CCc3cc(F)ccc3C2Cc2cccnc2)CC1)c1ccccc1 +CN(C)CCCNc1nc(NCc2ccc(C(F)(F)F)cc2)nc(NCc2ccc(C(F)(F)F)cc2)n1 +O=C(O)CCn1c2c(c3cc(NS(=O)(=O)c4ccc(F)cc4)ccc31)CCCC2 +O=C(O)C1CC2(CCN(c3ccc(-c4nc5ccc(C(F)(F)F)cc5[nH]4)cn3)CC2)Oc2ccccc21 +CCOC(=O)C(=O)CC(=O)C=Cc1cccn1Cc1cc(F)cc(F)c1 +CCc1ncnc(-c2ccc(C(=O)N3CCN(CC(F)F)CC3)c(Cl)c2)c1C#Cc1ccc(NC)nc1 +COc1ccc2cc(-c3nn(C(C)(C)C)c(N)c3C(N)=O)cnc2c1 +CSCCN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21 +CC(Oc1cc2oc(=O)n(CCC(=O)O)c2cc1Cl)c1ccccn1 +CC1(C)C=CC2=C(O1)C(=O)c1ccccc1C2=O +CC(NC(=O)c1ccnnc1)c1ccc(OC2CCN(c3ccnc(OCC(F)F)c3)C2)cc1 +O=C(NC(CCCCNc1cccc2ccccc12)C(=O)O)OCC1c2ccccc2-c2ccccc21 +OC(CNC1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1)COc1ccc(F)cc1 +COc1cccc(C(=O)c2cc(OC)c(OC)c(OC)c2)c1 +COc1ccc(CCNc2cc(-c3cccc(S(C)(=O)=O)c3)nc(OC)n2)cc1 +O=C(Nc1cc(C(=O)N2CCC(O)(CO)CC2)nn1-c1ccccc1)c1cc(-c2ccccn2)c(F)cc1Cl +CNc1ccc(C=Cc2ccc(OCCCCCCCCF)cc2)cc1 +Cc1nc(C)n(-c2ccc(Nc3cc(-c4ccn(C)n4)c(F)cn3)cc2)n1 +CCCNC(=O)C1CCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)CC1 +CCCCCN1C(=O)C2(COc3cc(F)c(F)cc32)c2ccccc21 +O=C(NCCC1CCN(Cc2ccccc2)CC1)c1cc[n+]([O-])cc1 +CC(=NN=C(S)N1CC2CCC(CC2)C1)c1cnc(C)cn1 +CCCN(CCC)C(=O)Cc1c(-c2ccccc2)nc2ccc(C(=O)OC)cn12 +CC(=N)N1CCC(Oc2ccc(N(Cc3ccc(-c4cccc(C(=N)N)c4)cc3)S(C)(=O)=O)cc2)CC1 +COc1nc(N)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cc(Cl)ccc1C)C2=O +O=C(NC1CCCCC1)c1ccc2[nH]c(-c3ccc(NC(=O)C45CC6CC(CC(C6)C4)C5)cc3)nc2c1 +CC(C)c1noc(COc2ccc(Cl)cc2OC2CNC2)n1 +O=C1N(Cc2cccc(Cl)c2)CCCC12CCN(c1nc3ccccc3[nH]1)CC2 +O=C(O)CC1CCc2c(c3ccccc3n2Cc2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)C1 +Cc1c(Br)cccc1C(=O)NCC1(c2ccc(C(F)(F)F)nc2)CCC(F)(F)CC1 +O=C(c1ccccc1)C1Cc2ccc(cc2)OCCCCC(C(=O)NO)C(CCCc2cc(Br)cc(Br)c2)C(=O)N1 +CC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cncc(N)c1 +CC(C)CCn1c(CN2C(=O)C(=NOc3ccccc3)c3ccccc32)nc2ccccc21 +O=C(O)C(=O)C1Cc2ccccc2CN1S(=O)(=O)C=Cc1ccccc1 +CC1(C)Cc2c(-c3ccccc3)c(-c3ccc(Cl)cc3)c(CC(=O)NS(C)(=O)=O)n2C1 +Cc1nc(N2CCN(C(=O)CC(C)C)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +O=S(=O)(c1cccc(F)c1)c1ccc2oc3c(c2c1)C1CCC(C3)N1 +CN(C)c1cc[n+](CCCCCCCCCCC[n+]2ccc(N(C)C)cc2)cc1 +COC1CC2(C)C(CCC3C4CCC(=CC#N)C4(C)CC(=O)C32)CC1O +CC(C)(C#N)c1cc(Cn2cncn2)cc(Sc2ccccc2)c1 +Cc1ccc(-c2ccc3n(c2=O)CC2CNCC3C2)s1 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+O=C(O)c1cccc(-n2c(Cl)ccc2-c2cc(Cl)ccc2OCc2ccccc2)c1 +CCOC(=O)CCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +Nc1c(S(=O)(=O)c2ccccc2)c2nc3ccccc3nc2n1CCN1CCOCC1 +Nc1ncc(-c2nc(N3CCOCC3)c3ccc(Nc4cccnc4)cc3n2)cn1 +COc1ccc(C(Cc2ccncn2)c2ccccc2)cc1OC1CCCC1 +COc1ccc(C)cc1NC(=O)OC1CC23CCCCC2(CC(NCc2ccccc2)C3)C1 +Cc1cccc(NC(=O)Nc2ccc(-c3ccc(N)c4c3CNC4=O)cc2)c1 +COc1ccc(-c2ccc(CSc3nnc(-c4ccncc4)o3)cc2)cc1 +[C-]#[N+]c1ccc(C(=O)Nc2cc(F)c(F)c(C3(C)CC(C(F)(F)F)OC(N)=N3)c2)nc1 +NCc1ncc(C23CCC(N(CCN4CCCC4)C(=O)Nc4ccc(F)c(C(F)(F)F)c4)C2C3)s1 +FC(F)(F)Cn1cc(C(NC2CCN(c3ccc(C(F)(F)F)cc3)CC2)c2cccnc2)cn1 +Cc1cc(Cl)cc(Cl)c1CC(=O)NC1COc2nc(Cl)ccc21 +O=C(NS(=O)(=O)c1ccc(F)cc1)N1CCC(N2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)CC1 +O=C(CSc1ccccc1)NCCCN1CCC2(CCc3ccccc32)CC1 +O=c1c2cn[nH]c2c2ccc(-c3ccc(C(F)(F)F)nc3)cc2n1CC(F)(F)F +CN1CCc2c(c3cc(C(F)(F)F)ccc3n2CCc2ccncc2)C1 +O=C(NC(CNC(=O)C1CCCn2c(C=CC3CCNCC3)nnc21)C(=O)O)OCc1ccccc1 +CC(C)Oc1ccc(NC2=CC(O)N(CC(=O)NC(CO)CO)C(=O)N2Cc2ccc(Cl)cc2)cc1F 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+CCCCNC(=O)C1CC(Cc2ccccc2)CN1C(=O)C(N)CC +Cc1c(C#N)[nH]c2ccc(CN3CCC(Nc4ncnc5sc(CC(F)(F)F)cc45)CC3)cc12 +Cc1cc(C(F)(F)F)ccc1CCc1cc(O)c(=O)[nH]n1 +COc1ccc(CC(Cc2ccc(NS(=O)(=O)O)cc2)(c2nc(C)no2)c2nc(C)no2)cc1 +CNC(=O)c1cccc2c1C(NC)CCC2c1ccc(Cl)c(Cl)c1 +CC(=O)c1c(C)cc(C)c(CSc2nc3ccc(NC(=O)c4ccc(C(C)(C)C)cc4)cc3s2)c1C +COc1ccc(OC)c(C(c2c(C)n[nH]c2O)c2c(C)n[nH]c2O)c1 +CC(=O)Nc1nc(C)c(-c2cnc(-c3cccnc3)o2)s1 +N#Cc1ccccc1Cn1c(N2CCCC(N)C2)ncc(Cl)c1=O +COc1cc2nccc(Oc3ccc4c(C(=O)Nc5ccc(Cl)cc5)cccc4c3)c2cc1C(C)=O +CCCCN1C(=O)C2Cc3c([nH]c4ccccc34)C(c3ccoc3)N2C1=O +COc1cccc(CNC(=O)c2cc3ccc(-c4cn[nH]c4)cc3n2CCN(C)C)c1 +CCc1c(C(=O)N2CCc3cc4ccnc(N5CCN(CC)CC5)c4cc32)cnn1-c1ccc(C#N)cc1 +COC(=O)C(CC(C)C)NC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2 +CC1(c2cc(NC(=O)n3ccc4cc(Oc5ncnc6c5CNC6)ccc43)n[nH]2)CC1 +COc1cccc(N(C)CC(=O)N2CCCC(c3ccccc3)C2CN2CCCC2)c1 +COCCCn1nc(C)c2ccc(C(C)N(C(=O)C3CNCCN3)C3CC3)cc21 +CCCc1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(OC(F)(F)F)c2)c1 +CC1CN(C(=O)C2CN(c3cccnn3)CC2c2ccc(F)cc2F)CC(C)C1(O)c1ccccc1 +Cc1cc(NS(C)(=O)=O)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(-n2ccnc2C)s1 +CC(Nc1nccc(-c2c(-c3ccccc3)nc3nc(N)ccn23)n1)c1ccccc1 +CCOc1ccc(-n2c(C(C)N(C(=O)Cc3ccc(F)c(C(F)(F)F)c3)C3CCOCC3)nc3ncccc3c2=O)cc1 +Cc1cc(C)cc(Sc2c(CNC=O)c(C)[nH]c(=O)c2I)c1 +Oc1cc2c(cc1O)CN(C(=S)NCCc1ccc(Cl)cc1)C2 +O=S(=O)(NCCCCCc1c[nH]cn1)NCc1ccc(Cl)cc1 +CCC(NC(C)CO)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F +CC1(c2cccc(Nc3ccccc3OC(F)F)c2)COCC(N)=N1 +O=C(NC1CC1)c1ccc(Cl)c(Nc2nncc3c2cnn3-c2c(F)cccc2F)c1 +Nc1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +COc1ccc(-c2nc3c(C(=O)NCC(=O)N4CCCC4C#N)ccnc3[nH]2)cc1 +Nc1ccnc(N2CCC(C(=O)Nc3ccc4ccccc4n3)(c3ccccc3)CC2)c1 +CCC(CC)n1cc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c(=O)c(-c2cccc(C(F)(F)F)c2)c1C +O=C1Cc2ccccc2N1CCCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +N#CN=C(Nc1ccc(F)cc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Br)cnc32)CC1 +Nc1ncc(-c2cccnc2)c2scc(-c3cccc(NC(=O)Nc4c(F)cccc4F)c3)c12 +O=C(Nc1cc(-c2ccccc2)cn(CC2CC2)c1=O)N1CCC(n2cc(-c3ccccc3)[nH]c2=O)CC1 +COCCOc1ccc(N(Cc2cnccc2C)C2CCN(C(C)CCNC(=O)c3c(C)cc(F)nc3C)CC2)cc1 +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)NCc1cccc(Br)c1 +CC(=O)c1cnc(N2CCn3c(nc4cc(CO)c(S(C)(=O)=O)cc43)C2C(C)C)nc1C(F)(F)F +O=C(O)c1ccc(NC(=O)c2c(Oc3ccc(F)cc3)cc(C(F)(F)F)cc2C(F)(F)F)cc1 +CCc1sc2ncnc(NN=C(C)c3cc(O)ccc3O)c2c1C +CCCCCCCC=CCCCCCCCC=C1CC(C=CC(=O)OC)(CO)OC1=O +Cc1ccc(C(=O)CSc2nc(O)c(C(C)C)c(Cc3cccc4ccccc34)n2)c(C)c1 +O=c1c2c[nH]nc2c2ccc(Nc3cccnc3)cc2n1CC(F)(F)F +Cc1ccccc1C(=O)NC(Cc1ccccc1)C(=O)CCC(=O)N1CCCC1C(=O)O +Cc1ccc(C(C)n2c3ccccc3c3c(N)nc(-c4ccccc4)nc32)cc1 +CC(Nc1cc(-c2ccc(N(C)C)cc2)nc(-n2cnc3ccncc32)n1)c1ccccc1 +CC(C)CC1(C(=O)O)CC(C(=O)Nc2ccccc2)C(c2nccs2)N1C(=O)c1ccc(C(C)(C)C)cc1 +O=C(NC1COCC1C(=O)NO)c1ccc(Cn2c(C(F)(F)F)nc3ccccc32)cc1 +COc1ccc2c(c1)CCN(c1noc(-c3cc(C(F)(F)F)cc(C(F)(F)F)c3)n1)C2 +COCC(C)Oc1ccc2[nH]nc(-c3cc(N4CCCC(F)(F)C4)ncn3)c2c1 +COc1cccc(CC2C(O)C(O)C(Cc3cccc(OC)c3)N(CC3CC3)C(=O)N2CC2CC2)c1 +CCONC(=N)c1ccc(-c2ccc(-c3ccc(C(=N)NOCC)cc3)o2)cc1 +COc1cccc(CN2C(=O)C3(N=C2N)c2cc(CCC4CC4)ccc2CC32CCC(OC)CC2)c1 +Cc1cc(C)c(Oc2cc(Nc3ccc(C#N)cc3)nc3ncnn23)c(C)c1 +CCN(CC)C(=O)C1CCC2C3CN(CC)C4=CC(=O)CCC4(C)C3CCC12C +COc1cccc(CNC(=O)C#Cc2cn(Cc3ccc(C(=O)O)cc3)c(=O)[nH]c2=O)c1 +CN1CCN(c2ccc(Nc3ncc4cc(C#N)c(=O)n(C5CCCC5)c4n3)cc2)CC1 +CCCC(=O)Nc1cc(-c2ccc3c(c2)OCO3)nc(-c2ccccc2)n1 +Cc1cccnc1-n1nc(C)c(-c2ccc(OC3CCN(C4CCC4)CC3)cc2)cc1=O +OCCN1CCN(c2ccc3cc2COCC=CCOCc2cccc(c2)-c2ccnc(n2)N3)CC1 +O=C(NCc1ccc(S(=O)(=O)N2CCCCC2)cn1)N1Cc2cn[nH]c2C1 +Cc1nc2sc(C(=O)NCc3ccc4c(c3)OCO4)c(N)c2c(C)c1Cl +CCN(CC)c1cccc(Nc2nc(Nc3cccc(NC(C)=O)c3)nc3c(C#N)cnn23)c1 +N#Cc1cc(Oc2ccc(-c3cccc(C(O)C(O)C(N)=O)n3)cc2)ccc1C(F)(F)F +Cc1cc(COc2ccc(S(=O)(=O)N3CCN(C4CCC4)C(C(=O)NO)C3)cc2)c2c(n1)CCCC2 +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(F)cc3OCC3CCNC(=O)C3)c12 +CCCS(=O)(=O)c1ccc(Cl)cc1C1NC(=O)NC1=O +N#CCOc1ccc(Nc2nc(Nc3cccc(O)c3)ncc2F)cc1 +COc1cccc(OC)c1C1CCCCC(=O)N1Cc1ccc(-c2ccccc2)cc1 +C=CC(=O)Nc1cccc(CC)c1Nc1ncc(OCc2c(Cl)c(OC)cc(OC)c2Cl)cn1 +CCCn1c(=O)c2nc(-c3cccnc3)[nH]c2n(CCC)c1=O +CC(C)OC(=O)N1CCC(Oc2cccc3c2CCN3c2ccc(S(C)(=O)=O)cc2)CC1 +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2ccccc2Cl)c(C)c1 +Cc1nccn1-c1ccc(-c2cn(CC(=O)Nc3cccc(Cl)c3Cl)nn2)cn1 +CC(NC(=O)Nc1cc2[nH]nc(NCc3ccccc3)c2cn1)c1ccccc1 +O=C1Cc2cc(C(=O)NC3CC4CCC(C3)N4S(=O)(=O)CC3CCNCC3)ccc2N1 +COc1cccc2c3c(=O)n(C4C5(C)CCC(C5)C4(C)C)ccc3n(CCN3CCOCC3)c12 +CC(C)(O)CN1CCC(NC(c2ccc(Cl)cc2)c2cccnc2)CC1 +O=C(NC(=S)Nc1ccc(S(=O)(=O)N(Cc2ccc(O)cc2)c2ccccc2)cc1)c1ccc2cccnc2c1 +Cc1ccc(CN2CCN(CC(=O)N3c4ccccc4CC3C)CC2)cc1F +COC(=O)C=Cc1cccc(N(Cc2ccc(C=Cc3scnc3C)cc2)C(=O)C(C)C)c1 +O=C(Nc1ccc(O)cc1OCC(O)CN1CCC2(CC1)Cc1cc(F)ccc1O2)NC1CC1 +CS(=O)(=O)c1ccc(-c2c(-c3ccc(F)cc3)nn3nc(S(C)(=O)=O)ccc23)cc1 +[N-]=[N+]=Nc1ccc(C(=O)NCCCCCCC(=CC(N)C(=O)O)CP(=O)(O)O)cc1 +N=C(N)NCCCC1C(=O)N(S(=O)(=O)c2ccc(-c3ccccc3)cc2)C1C(=O)O +CCOC(=O)N1CCC(n2cnc(-c3ccc(F)cc3)c2-c2ccnc(N)n2)CC1 +Cn1cc(C=C2C(=O)Nc3ccc(S(N)(=O)=O)cc32)c2ccccc21 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+CCOC(=O)c1ccc(COC2CCN(c3ccc(C)nn3)CC2)cc1 +Cc1ccc(C)c(-c2cc(-c3ccc(F)cc3)c(C=CC3CC(O)CC(=O)O3)c(C(C)C)n2)c1 +Cn1c(=O)n(CC(C)(C)C)c2ccc(C3=CC4CN(C(=O)c5ncco5)CC4C3)nc21 +COc1cc(Nc2c(C#N)cnc3cc(-c4ccc(CN5CCOCC5)cc4)c(OC)cc23)c(Cl)cc1Cl +O=C(CCc1cccc2ccccc12)NC1=C(C(=O)O)CCCC1 +CCCCCCCCCC(CC(=O)NO)C(=O)NC(C(=O)NC)C(C)(C)C +COc1ccc(S(=O)(=O)n2ccc3ccnc(-c4ccc(F)cc4)c32)cc1 +OC1(c2ccc(Cl)cc2)CCN(CCCCc2ccc(F)cc2)CC1 +OCC1OC(n2cnc3c(NCC=Cc4ccccc4)ncnc32)C(O)C1O +Clc1ccc(C2=Nn3c(nnc3-c3cccnc3)SC2)cc1Cl +Cc1nc(N2CCC(O)(CCO)CC2)nc2ccc(NC(=O)C=Cc3ccc(Cl)cc3)cc12 +O=C(NCc1ccc(Cl)cc1Cl)N1CCC(Oc2ccccc2)CC1 +O=S1(=O)C=Cc2cc(-n3cc(-c4ccc(OC(F)(F)F)cc4)nn3)ccc2O1 +CCOc1ccc2c(c1OC)CN1CCc3cc(OC)c(O)cc3C1C2 +CC(C=CC1CC2(CO2)CC(C)(C)O1)=CCC1CCC(NC(=O)C=CC(C)OC(=O)N(C)CCN(C)C)CC1 +O=C(NC1CCN(c2ccccn2)CC1)c1nn(-c2ccc(Cl)cc2Cl)c2c1CCCC2=Cc1ccc(F)cc1 +CC1Nc2cc3c(cc2C1C)c(C(F)(F)F)cc(=O)n3C +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCCNCC1 +COc1ccc(-c2nc3cc(-c4nc5cc(CCN(C)C)ccc5[nH]4)ccc3[nH]2)cc1 +COc1cc(-c2cnc(C)n2C)ccc1Nc1cc2cc(-c3cnn(CC(F)(F)F)c3)ccc2cn1 +N#Cc1cncc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)c1 +CCN(c1cc(OC)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1C)C1CCC(N(C)C)CC1 +COc1cc(-c2ccc3c(c2)OCO3)cc(C=O)c1O +COc1cc(Oc2ncccc2-c2n[nH]c(Nc3ccc4c(c3)OCO4)n2)cc(OC)c1OC +CN(CCCCCCCN1C(=O)c2ccccc2C1=O)Cc1cccc(Cl)c1 +Cn1cc(C2=C(C(=O)CBr)C(=O)NC2=O)c2ccccc21 +Cc1cc(-c2nnc(NCC3OCCO3)o2)nc2c(C(C)(C)C)cc(OCC(F)(F)F)cc12 +Cc1ccc(Cn2c(=Nc3ccc(OC(C)C)c(F)c3)[nH]c(=O)n(CC(=O)NC(C)C(=O)O)c2=O)cc1 +Clc1ccc(-n2cncn2)c(Cc2nc3c(NCCC4CCCCN4)nccc3o2)c1 +CCC(=O)NC(C(=O)N1CCC(O)(c2ccc(Cl)cc2)C(C)(C)C1)C(C)C +CC(O)(COc1ccc(Cl)c(F)c1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3cnc4[nH]ncc4c3)c2)c2cncnc21 +Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3)ccc12 +Nc1ncnc(N2CCC(C(O)c3ccc(F)cc3)CC2)c1-c1ccc(F)cc1 +O=C(c1cnc2ccc(-c3cc(Cl)c(O)c(Cl)c3)cc2c1Nc1ccc(N2CCC(O)C2)nc1)C1CC1 +CCn1nc(-c2cccc(-c3ccc(O)cc3F)c2)cc(NC(=O)Nc2c(Cl)cncc2Cl)c1=O +COCCCNC(=O)c1cn2cc(-c3cnc(N)nc3)nc(N3CCOCC3)c2n1 +OC(CN(Cc1cccc(OC(F)(F)C(F)F)c1)c1cccc(Oc2ccccc2)c1)C(F)(F)F +O=C(O)CC(NC(=O)c1cncc(S(=O)(=O)NC2CC2)c1)C(=O)CSCc1ccc(F)cc1 +COC1COCCC1NC1CC2OCCC2(C(=O)N2COc3ccc(C(F)(F)F)cc3C2)C1 +CN1C(=O)C(=C2CC(c3ccccc3)N(C(=O)CCl)N2)C(=O)N(C)C1=O +CCc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2Cl)CC(C)S3)cc1 +COc1ccc(Cn2c(C(N)=O)cc3c2-c2nc(Nc4ccccc4)ncc2CCC3)cc1 +N#Cc1cccc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)c1 +O=C(CCCCc1ccn(Cc2ccc(OCc3ccccc3)cc2)n1)NO +O=C(NC1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3NCCC4)ccc2F)CC1)c1ccccn1 +CCOc1ccc(NC(=O)c2ccc(Cl)nc2)c([N+](=O)[O-])c1 +CCN1CCCC(n2cc(S(=O)(=O)c3ccc(Cl)s3)c3cccnc32)C1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1NC(=O)c1cncnc1 +CCc1c(COC(=O)NC)c(COC(=O)NC)c2n1-c1ccccc1C2 +CC(NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1)C(C)(C)C +CCN1C(=Cc2cc[n+](CC)c3ccccc23)C=Cc2ccccc21 +Clc1ccc2c(NCCCCCCCNc3c4c(nc5ccccc35)-c3ccccc3C4)c3c(nc2c1)CCCC3 +Cc1c(-c2ccnc(N)n2)sc2ccc(C(N)c3ccccc3)cc12 +CCCCCCC(C)CC1=C(O)C(=O)c2c(C)cccc2C1=O +CC(C)CCC(=O)C(CC1CCCCC1)NC(=O)C(CC(C)C)NC(=O)Cc1ccccc1 +CC(C)n1cc(-c2cnc(Nc3cccc(Cn4nc(-c5cnn(C)c5)ccc4=O)c3)nc2)cn1 +Cc1ccc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)s1 +CC(=O)c1cnc2ccc(-c3ccc(O)cc3)cc2c1NC1CCC(CN(C)C)CC1 +COCCC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(Br)cc2)c1 +O=C(Cc1cccc2cnccc12)Nc1scnc1-c1cnccn1 +C=CCN(C)CCCCCCOc1ccc2c(-c3ccc(Br)cc3)coc2c1 +CNC(=O)NC(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 +Fc1ccc(-n2cc(OCCN3CCOCC3)c3cc(Cl)ccc32)cc1 +O=C(Nc1nccc2ccccc12)C1CCC(N2C(=O)C3C4CCC(C4)C3C2=O)CC1 +NC(=O)COc1ccc(C=C2SC(=O)N(CC(=O)O)C2=O)cc1 +N=C(N)NCCCC(NC(=O)c1coc(C(c2ccccc2)c2ccccc2)n1)C(=O)O +Cc1cc(C)cc(-n2nc(C)c3c(=O)oc4ccccc4c32)c1 +Cn1ncc(C(=O)N2C3CCC2CC(Nc2n[nH]c4ccc(F)cc24)C3)c1Cl +CC1(C)CCC(C)(C)c2cc(C3(c4ccc5cc(C(=O)O)ccc5c4)SCCS3)ccc21 +Cc1cccc(C)c1N1CC(CN(C)C)(C(=O)Nc2cc(C3CC3)cc(C(F)(F)F)c2)C(C)C1=O +CCN(CC)c1nc(NC(=O)Nc2ccccc2)c2ccccc2n1 +COc1ccc2ncc(C(F)(F)F)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +CCCN(CCCCCCNc1nc(N)n2nc(-c3ccco3)nc2n1)CCc1cccc2c1CC(=O)N2 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+N=C(N)c1ccc(NC(=O)c2ccc3c(c2)NC(CC(=O)O)CN(CCc2ccccc2)C3)cc1 +Nc1nc2c(cnn2CCCc2ccc(C(=O)O)cc2)c2nc(-c3ccco3)nn12 +CC(O)C1OC(OC2C(N)CC(NC(=O)C(O)CCN)C(O)C2OC2OC(CN)C(O)C2O)C(N)C(O)C1O +O=C(c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1)N(Cc1ccccc1)Cc1ccccc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(C#N)cnc32)cc1NC1CCC(N)C1 +CS(=O)(=O)Nc1ccc2[nH]cc(C(=O)CN3CCC(Cc4ccccc4)CC3)c2c1 +Oc1c(-c2nnc(Cc3ccc(F)cc3)[nH]2)ncc2cccnc12 +CNS(=O)(=O)Cc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 +COc1ccc(NC(=O)c2ccccc2NC(=O)c2ccc(C(C)(C)C)cc2)cc1C(=O)O +CN1CCC(CNC(=O)Nc2ccccc2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +CC(C)(C)c1ccc(C(=O)NCCCCNc2ccnc3cc(Cl)ccc23)cc1 +O=C(CC1CCNCC1)N1CCC(NS(=O)(=O)c2cc(S(=O)(=O)c3ccccc3)ccc2C(F)(F)F)CC1 +CC(C)c1cc(-n2cc(-c3ccc(CN4CCN(Cc5ccccc5)CC4)cc3)nn2)c(O)cc1O +CN(C)C(=O)c1cccc(-c2cnc(N)c(-c3nc4cccc(N5CCNCC5)c4n3C)n2)c1 +CC(=O)NCC(C)c1ccc(C#Cc2cnc(OC3CCC3)nc2)cc1 +COC(=O)CCc1cnc2c(c1)c(NCCO)c(C(=O)NCc1ccc(F)cc1F)c(=O)n2O +CCC1(C(=O)O)CCc2ccc(OCCCOc3ccc(C(F)(F)F)cc3Cl)cc2O1 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+COc1cc(CC(=O)NCC(COC(=O)C(C)(C)C)Cc2ccc(C(C)(C)C)cc2)cc(Br)c1N +COC(=O)c1cc2ccccc2cc1-n1nc(C)cc1C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1 +c1cc(NC2CCCC2)n2nc(-c3ccc(OCC4CC4)cc3)c(-c3ccnc(NC4CCCC4)n3)c2c1 +CCCN(C(=O)c1ccc([N+](=O)[O-])c(C)c1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O +O=C(Nc1cc(-c2ccccn2)nn1Cc1ccccc1)c1nc(C2CC2)ccc1Nc1cncnc1 +Cc1nc(NC(C)c2cccc(-c3cnc(N)nc3)c2)cc(-c2ccc(F)c(F)c2)n1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(F)cccc3nc2-1 +COc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCC(N(Cc4ccccc4)C(C)=O)CC3)cc2)cc1 +COc1ccc(-c2cc(NC(C)=O)cc(-n3cnc4cc(-c5cnn(C)c5)ccc43)c2)c(F)c1 +Clc1cnc(NCC2CCCNC2)cc1-c1cccc(NCC2CCOCC2)n1 +CC(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(C#N)cc3)c2)c2cncc(F)c21 +CCNc1cc2c(cc1Cl)NC(=O)Nc1cnc(C#N)c(n1)OCCCCCO2 +CC1(O)CCC(NC(=O)c2cc(NC(=O)c3cc(-c4ncccc4F)c(Cl)cc3Cl)n(-c3ccccc3)n2)CC1 +COc1cccc(C2=NN(c3ccccc3)C(c3ccc(Br)cc3)C2O)c1 +NC(=S)Nc1ccc2c(c1)Cc1cc(NCc3ccccc3)ccc1-2 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-c3cnco3)ncc(F)c12 +CN(C(=O)Nc1cnc(-c2ccccc2)cn1)C1CCC2(CC1)OC(=O)c1ccncc12 +O=C1C(NS(=O)(=O)c2ccc3c(Cl)c[nH]c3c2)CCN1c1cc2c(cc1F)CNCC2 +CCC(c1cc2c3c(c1)CCN3C(=O)CC2)n1ccnc1 +Cc1cc2c(cc1C=Cc1ccsc1S(=O)(=O)Nc1onc(C)c1Br)OCO2 +CNC(=O)Nc1cc(CCOc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1 +COc1ncc(-c2cc(C(=O)Nc3ccc(OC(F)(F)F)cc3)ccc2Cl)cn1 +CN1CCN(c2cc(C(=O)N(C)Cc3ccccc3)c3ccccc3n2)CC1 +CCN(C1CCC(N2CCN(c3ccccc3OC(C)C)CC2)CC1)S(=O)(=O)c1ccc(OC)c(OC)c1 +O=[N+]([O-])c1ccc2sc3c(Nc4cccc(Br)c4)ncnc3c2c1 +Cc1ccc(N2CC(O)=C(C(=O)Nc3ccc(OCCCCCCCn4cnnn4)cc3)C2=O)cc1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccccc1)Cc1ccc(Oc2cccc(CCCC(=O)O)c2)cc1 +COCCc1sc[n+](CCCCc2cccc(CCCC[n+]3csc(CCOC)c3C)c2)c1C +COc1ccc(OC)c(C2CC(=O)C3=C(C2)NC(=O)CC3c2ccc([N+](=O)[O-])cc2)c1 +Cc1cc(Cl)c(C(=O)Nc2cc(C(=O)NCC(C)(C)O)nn2-c2ccccc2)cc1-c1ncccc1F +COc1cc(CNC(=O)C2(Cc3ccccc3F)OC(=O)N(C(C)c3ccccc3)C2=O)cc(OC)c1 +O=C(O)C(=O)Nc1ccc(NC(=O)c2cc(Br)c(Br)[nH]2)cc1 +Cc1ccc(C2=C(c3ccc(S(C)(=O)=O)cc3)CCC2)cc1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC(C)(C)C)C1c1ccccc1C(F)(F)F +CCN(CC)C(=S)NCCCNc1ccnc2cc(Cl)ccc12 +O=C(Cc1ccc(F)cc1)NC(=O)Nc1ccc(Oc2ccnc3[nH]cc(C(=O)NCc4cccnc4)c23)c(F)c1 +CCCN(CCCC(=O)OCC)CCc1cccc2c1CC(=O)N2 +CC#CCOc1ccc(S(=O)(=O)N2CC(S)C2)cc1 +COc1cc(-c2cc(C#N)c(NC(C)c3ccc(F)cc3)nn2)ccc1-n1cnc(C)c1 +Cc1ccc(Nc2ncnc3c2nnn3Cc2ccccc2Cl)cc1 +N#CC1CCCN1C(=O)CNC1CCC(NC(=O)C2CCCCC2)CC1 +CCOC(=O)CCCCC(=O)c1[nH]c(O)nc1CN1CCOCC1 +CN1C(=O)C(NC(=O)NCc2ccccc2)N=C(c2ccccc2)c2ccccc21 +CN1C(=O)CCc2cc(-c3cncc(CC(=O)Nc4cccc(Cl)n4)c3)ccc21 +COC(=O)C(C)(C)NC(=O)c1ccc(N2CCCC2)c(OCC2CC2)n1 +CCCCC(N)C(=O)Nc1ccc(C(=O)NC(Cc2ccc(O)cc2)C(=O)OC)cc1N +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)c2ccc3c(cnn3CCCNc3ccccn3)c2)C(=O)O)c(C)c1 +O=C(NC1CN2CCC1CC2)c1cc2cccc(F)c2s1 +Cc1cc(C)c(S(=O)(=O)NC(Cc2c[nH]c3ccc(C#N)cc23)C(F)(F)F)c(C)c1 +Cc1cc2nc(CCc3nc4c(C)ncc(C)n4n3)ccc2cc1F +CCn1c(N)c(C(=O)NC)c(=O)c2ccc(C#CC(C)(O)COC)nc21 +O=C(Nc1cc2cc[nH]c(=O)c2cc1Cl)C1CCNC1 +Cc1n[nH]c(C)c1-c1cccc(-c2cnc(N)c(C(=O)NC3C4CC5CC3CC(O)(C5)C4)n2)c1 +O=C(O)CCCOc1cccc(CCCCCCOc2cc(-c3ccccc3)cc(-c3ccccc3)n2)c1CCC(=O)O +CC(C)(C)OC(=O)NC(Cc1ccc(NS(=O)(=O)O)cc1)c1nc(-c2cccc(C(F)(F)F)c2)cs1 +O=C(NCc1ccc(S(=O)(=O)c2ccccc2)cc1)N1Cc2ccccc2C1 +O=C(NCc1ccc(S(=O)(=O)c2cc(F)cc(F)c2)cc1)c1cc2cnccc2[nH]1 +CC(=O)OC1CCC2(C)C(CCC3C2CCC2(C)C(c4ccc(=O)oc4)CCC32O)C1 +CN(C)CCN(Cc1ccccc1)S(=O)(=O)c1cccc(N2CCN(c3cccc(Cl)c3)CC2)c1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)CCC1=NNCCN12 +Cc1nccn1-c1cnn(C)c(=O)c1-c1ccc(CC(NC(=O)c2c(Cl)cccc2Cl)C(=O)O)cc1 +N#Cc1ccc(Oc2ccc(-c3cccc(CNCCN4CCNC4=O)n3)cc2)cc1 +CCn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC(N)C(OC)CC1 +COc1ccc(F)c(-c2ccc(C3CCc4ccc(C(C5CC5)C(C)C(=O)O)cc4O3)nc2)c1 +O=C(C=Cc1ccc(Br)cc1F)N1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1 +O=C(CC1CCN(S(=O)(=O)c2ccccc2)CC1)N1CCC(C2c3ncc(Br)cc3CCc3cc(Cl)cc(Br)c32)CC1 +CS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)C=C(c1c(O)c(-c3cccs3)nn(CC3CCCC3)c1=O)N2 +O=c1c(N2CCc3ccccc32)nc2ccccc2n1C1CCN(C2CCCCCCC2)CC1 +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCN(C6CC6)CC5)ncn4)c3c2)cn1 +COC(=O)C1C(c2ccc(-c3cccc(F)c3)cc2)CC2CCC1N2C +CC(C)CC(NC(=O)C(CCc1ccccc1)CP(=O)(O)CCCCNC(=O)Nc1ccccc1)C(=O)Nc1ccccc1 +CCOC(=O)CCc1ccc(CCNc2nc(N)c3ncn(C4OC(CO)C(O)C4O)c3n2)cc1 +CC(=O)NCC1OC(n2cnc3c(NC4CC5CCC4C5)ncnc32)C(O)C1O +N#Cc1ccc2c(c1)C(=O)NC(C(=O)NC1(C#N)CC1)Cc1ccc(c(Cl)c1)OCCCCO2 +CC(Oc1cc2onc(CCC(=O)O)c2cc1Cl)c1ccc(F)cn1 +C=CCn1c(NS(=O)(=O)c2ccccc2)c(C#N)c2nc3ccccc3nc21 +Cc1cc(NC(=O)CCNC(=O)Nc2nc(C)c(-c3ccc(S(C)(=O)=O)c(F)c3)s2)no1 +CCOc1cc(=O)n(C)cc1-c1cc(NC(=O)Cc2ccc(Cl)cc2F)ccc1Oc1ccc(F)cc1F +NC1CCN(C(=O)c2ccc3[nH]c(-c4cc5ccccc5nc4O)cc3c2)C1 +COC(=O)Nc1nc2cc(C(=O)c3cc(CC(=O)OC(C)(C)C)cs3)ccc2[nH]1 +O=C(Nc1cccc(O)c1C(=O)O)c1ccc(Br)c(Oc2ccccc2)c1 +c1cncc(Cc2nnc(-c3ccc(N4CCC5(CCc6ccccc6O5)CC4)nn3)o2)c1 +CC1(F)C(O)C(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)OC1(C#N)c1ccc2c(N)ncnn12 +Cc1cc2c(cc1Cl)N(C(=O)Nc1ccc(Oc3cnccc3C)nc1)CC2 +N#Cc1ccc(C(=O)NC(=S)N2CCc3c(OCCCCCOc4ccc(Cl)cc4)cccc32)cc1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)nc3cc(CN(C)CCO)ccn23)n1)c1ccccc1 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+CN(C)C1CC=C2C=C3CCC4(C)C(c5ccc6ccncc6c5)CCC4C34CCC2(C1)O4 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NC3CCCCCC3)CC2)c(C)c1 +CC(C(=O)NCc1ccc(C(F)(F)F)cc1N1CCOCC1)c1ccc(NS(C)(=O)=O)c(F)c1 +O=C(O)c1ccc(C=NOC(c2ccc(OCc3ccc4ccccc4n3)cc2)C2CCCCC2)cc1 +CC(C)N(CC1CC2c3ccccc3Cc3ccccc3N2O1)C(C)C +Cc1sccc1C1(c2cccc(-c3cncnc3)c2)N=C(N)N(C)C1=O +COCC(C)Oc1cc(OC(C)Cc2ccccc2OC)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 +CN(C)c1ccc(-c2c(COc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cn1 +CS(=O)(=O)Nc1ccc(C(=Cc2c(C(=O)O)[nH]c3cc(Cl)cc(Cl)c23)C(=O)O)cc1 +CCCN(C)CCC1=C(Cc2cnccn2)c2ccccc2C1 +CCCS(=O)(=O)NC(C(=O)NC(CCSC)C(=O)NCc1ccc(C(=N)N)cc1)C(C)O +O=C(CCCCCCC(=O)Nc1cccc(-c2cnnn2-c2ccccc2)c1)NO +CC(=O)NC(Cc1ccc(F)cc1)C(O)CNC1CC2(CCC2)Oc2ncc(CC(C)(C)C)cc21 +COc1ccc(-c2cncc(C(F)(F)F)c2)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C(O)c1ccccc1)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 +CC(=N)N1CCC(Oc2ccc3c(c2)OCC(=O)N3Cc2cccc(-c3cccc(C(=N)N)c3)c2)CC1 +CCNc1nc2ccc(C#CC(C)(O)c3cc(C)on3)cc2n1-c1ncnc(N)n1 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+O=c1c(Cc2ccccc2)c[nH]c2c(-c3cccnc3)cnn12 +CCCCNc1nc(N)nc(CC)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1 +CCCCn1cc(C(=O)c2cccc3ccccc23)c2cccc(OC)c21 +CCC(C)(C)C(=O)OC1C(CO)C(C)C=C2C=CC(C)C(CCC3CC(O)CC(=O)O3)C21 +CN(C)C(=O)N1CCN(C(c2cncnc2)c2ccc(Cl)cc2F)CC1 +Nc1[nH]c2ccccc2c2nc(-c3ccccc3)nc1-2 +O=C(NCCCCCCS)c1cc(-c2ccccc2)n[nH]1 +NCCCN(CCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)CC1CC1 +CCn1cc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2cccc(Cl)c2)C(N)CC3)cn1 +Cc1cc(=O)[nH]nc1-c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 +Nc1ncc(-c2ccc(-c3ccc(C(F)(F)F)cc3S(=O)(=O)NCCO)cn2)cn1 +CNC(C)C(=O)Nc1cc(-c2ncnc3c(C)nn(C)c23)cc(NC(=O)c2cc3c(cn2)COC3)n1 +CCN(Cc1ccccc1)C(=O)C(=O)c1c(-c2ccc(F)cc2)[nH]c2ccccc12 +Cc1nc2n(c(=O)c1CCN1CCN(c3cccc4c3CCS4)CC1)CCCC2O +C=CCNC(=O)c1ccccc1Sc1ccc2c(C=Cc3ccccn3)n[nH]c2c1 +Cc1ccc2c(c1)C(=Nc1ccc(NC(=O)Nc3ccc(S(N)(=O)=O)cc3)cc1)C(=O)N2 +CNC(C)C(=O)NC(C(=O)NC1CCCN(C(=O)Cc2ccccc2)C1)C1CCCCC1 +Cc1ccc(C2=NN(c3nc(-c4ccc(Br)cc4)cs3)C(c3cccs3)C2)cc1 +COc1c(OCC(O)CN(C)C)ccc2c1N=C(NC(=O)c1cccnc1)N1CCN=C21 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+[O-][n+]1nc2c(I)cnn2c2cc(Oc3ccccc3)ccc21 +O=C(Nc1ccc(-c2ccc(O)cc2)cc1)Nc1ccc(-c2ccnc3[nH]cnc23)cc1 +CCCCC1Nc2cc(NC(=O)OCC)nc(N)c2N=C1C +CCCCCCNC(=O)Oc1cccc(-c2cc(C(=O)OCC)nn2-c2ccccc2)c1 +Cc1cc(Nc2n[nH]c3ncc(F)cc23)nc(C2CCCCC2)n1 +CN(C)Cc1ccc(-c2ccc(NC(=O)Nc3cccnc3Oc3ccccc3C(C)(C)C)c(F)c2)cc1 +CC1(C)Oc2cc(C34CC5CC(CC(C5)C3)C4)cc(O)c2C2CC(O)CCC21 +Cn1cc(-c2cnn3c(N)c(-c4ccoc4)c(C4CCCNC4)nc23)cn1 +CC(C)Nc1cc(NCc2ccccc2)nc(-c2ccc(S(C)(=O)=O)cc2)n1 +CCCc1[nH]c(=O)c(Cc2cc3cc(OC)ccc3nc2NCCOC)c2cc(OC)c(OC)cc12 +COc1cccc(CC(=O)Nc2nc(-c3ccnc(F)c3)cs2)c1 +Brc1cccc(Nc2ncnc3ccc4cc[nH]c4c23)c1 +[H]C([H])([H])N(C(=O)c1c(F)cccc1Cl)c1ccc(-c2cc(NC(C)=O)nn2C(C)C)cc1OCC1CCC1 +COc1ccc(Nc2nccn(C(C)C3CC3)c2=O)c(C(F)(F)F)n1 +O=C(NC(Cc1c[nH]c2ccccc12)C1=NNC(CCc2ccccc2)N1Cc1cccs1)C1CCNCC1 +COc1nccc2c1C(=O)CC1(CCN(C(=O)c3cc(C)c4[nH]ncc4c3)CC1)O2 +CC(N)(COP(=O)(O)O)C(=O)Nc1ccc(OCCc2cccc3ccccc23)cc1 +Oc1cccc(-c2nc(N3CCOCC3)c3[nH]ccc3n2)c1 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NC)cc2C)ncn1 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+COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(sc5cccc(OC)c54)c3=O)CC21 +[N-]=[N+]=NCC1OC(n2cc(Br)c3c(Cl)ncnc32)C(O)C1O +CCNC(=O)C1OC(n2cnc3c(N)nc(NCCN4CCN(c5ccc(C(F)(F)F)cc5)CC4)nc32)C(O)C1O +N#Cc1ccc(N2C(=O)C3C(O)CCN3C2=O)c(F)c1F +CN1C2CNCC1CC(NC(=O)N1CC(C)(C)c3ccccc31)C2 +c1cc(Nc2ncnc3ccc(-c4ccc5[nH]ncc5c4)cc23)c2cn[nH]c2c1 +CNC(=O)c1c(NC(=O)c2nc(N3CCN(C)CC3)cnc2Nc2cncnc2)cnn1C +CNC(=O)C(CC(C)(C)C)NC(=O)c1cccc(Cc2ccc(F)cc2)n1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC1CCC(N)C1 +Cn1cc(-c2cnc(N)c3c(-c4ccc5c(c4)CCN5C(=O)Cc4ccccc4)csc23)cn1 +CCN1CC=C(c2c[nH]c3ccc(NC(C)=O)nc23)CC1 +Cc1nc(-c2ccc3c(c2)c(C#N)cn3Cc2ccccc2)sc1C(=O)O +Cc1c(C)n(Cc2ccc(-c3ccccc3)cc2)c2ccc(C(=O)NC(C)c3cccc(Cl)c3)cc12 +C=CC(=O)Nc1cccc(-n2cnc3cnc(Nc4ccc(OC)cc4)nc32)c1 +COc1cc(C(=O)c2ccc(-c3csc(NC(=O)C(N)Cc4ccc(F)cc4)n3)cc2-n2cncn2)cc(OC)c1OC +CC1CCCC(N2CCC(c3c(F)ccc(Cl)c3F)=CC2=O)c2cc(ccn2)-c2ccc(C#N)cc2NC1=O +COc1cc(F)cc2c1nc(C)c1c(C)nc(-c3cnccc3C)n12 +C=CCN(C(=O)OCc1ccc([N+](=O)[O-])cc1)C1CCN(CCC(Cn2cnc3ccccc32)c2ccccc2)CC1 +Cc1cc(=O)n(CCCOc2cccc(Cl)c2)c(N2CCNCC2)n1 +COc1ccc(NC(=O)Nc2ccc(Cn3cc4c(=O)[nH]cnc4n3)cc2)cc1 +O=C1CCCCCN1Cc1nnc(SCc2nc3ccccc3s2)n1-c1ccccn1 +COC1(c2ccccc2)CCN(Cc2ccn3c(CC4CC4)nnc3c2C(F)(F)F)CC1 +CC1=C(C(=O)c2ccc(F)c(F)c2)C(c2cccc(O)c2)NC(=S)N1C +CCOc1ccc(Cc2nnc(CN(c3cccc(Cl)c3Cl)S(=O)(=O)c3ccc(C(F)(F)F)cc3)o2)cc1 +O=c1cc(-c2ccccc2)oc2cc(OCCN3CCN(c4ccccc4)CC3)ccc12 +O=C(O)c1ccc(OC2CCN(C(=O)NC3CC3c3ccccc3)CC2)cc1 +CC1CN(CCOC(=O)C2Cc3ccc(O)cc3CN2)CCC1(C)c1cccc(O)c1 +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1Cl)CC2 +COc1ccc2c(c1)CCOC21CCN(CCC(C(=O)NCc2cc(F)cc(C(F)(F)F)c2)c2ccc(F)cc2)CC1 +C=C(CN1CCOCC1)C(=O)Nc1cc2c(cc1OC)nc(Nc1ccccc1C)c1cncn12 +Cc1c(Cl)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 +Cc1nn(C2CCCC2)c(C)c1S(=O)(=O)NC(C)CNc1cccc2c1cnn2-c1ccc(C#N)cc1 +Cc1ccc(S(=O)(=O)N2CCc3cc(C(=O)NCCN(Cc4ccc(Cl)cc4)C(C)(C)C)ccc3C2)cc1 +NC(=O)c1cccc2[nH]c(-c3ccc(C4CCCNC4)cc3)nc12 +CN(C)CCCN1c2ccccc2CCc2ccc(C#CCOCCOCCc3cccc4ccccc34)cc21 +O=C(NCc1ccc(Cl)cc1)c1cc2cccc(O)c2cc1O +Cc1cc(NC(=O)c2cnn3cccnc23)n(-c2cc(C#N)ccc2C)n1 +COCCNC(=O)Nc1cc2[nH]nc(OC)c2c(COC)n1 +C=CC(=O)NC1CCN(c2nc(Nc3ccc(N4CCN(C)CC4)cc3)c3ncn(CCO)c3n2)C1 +N#Cc1ccc(C(=O)CC2CCN(CC3CC3)CC2)cc1 +CC(C)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)N1CC(C(=O)O)C1 +CC1CCN(C2CCN(c3ccc(Nc4ncc5cc6n(c5n4)C4(CCCCC4)CNC6=O)nc3)CC2)C1 +CCc1ccc2c(c1)sc1nc(C(=O)c3ccccc3)cn12 +N=C(N)c1ccc(Oc2ccc3c4ccccc4n(Cc4ccc5ccc(C(=N)N)cc5c4)c3c2)cc1 +Nc1nc(N)c2nc(CCc3ccc(C(=O)NC(CCCNC(=O)c4ccccc4C(=O)O)C(=O)O)cc3)cnc2n1 +CN1CCc2ccc(C(=O)CCCN3CCC(c4ccc(Cl)cc4)CC3)cc2CC1 +N#Cc1cc(S(=O)(=O)Nc2nccs2)ccc1Oc1ccc(F)cc1-c1ccc(F)nc1 +Nc1ncnc(N2CCC(Cc3ccc(Cl)cc3)CC2)c1Br +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(NC2CCc3cc(Br)ccc32)C1 +CCC(C)C(=O)OC1CCC=C2C=CC(C)C(CCC(=O)CC(O)CC(=O)O)C21 +COc1ccc(CNC2COC(C(c3ccccc3)c3ccccc3)CC2O)cc1F +COC(=O)CCc1ccc(OCC(O)CNC(C)(C)C)cc1 +CC1(C)CC=C(c2cc(C3(N4CCOCC4)CCOCC3)ccc2NC(=O)c2ncc(C#N)[nH]2)CC1 +Cc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc([N+](=O)[O-])c(N2CCC(C(=O)O)CC2)cc1Cl +CCCNC(=O)NCc1cnc2c(ccn2-c2cc(NC(C)C)c(C(=O)NCC(F)C(C)(C)O)cn2)c1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2Cl)c1F +O=C1NC(=S)SC1=Cc1cc(-c2csc3ccccc23)ccc1OCc1ccccc1 +CN(C(=O)c1ccccc1)c1nc(-c2ccncc2)cs1 +c1cc2c(ncn3nnc(C4CCN(Cc5cncs5)CC4)c23)[nH]1 +CC(=O)NC1(Cc2cccc(Nc3nccs3)n2)CCC(Oc2cccc(Cl)c2F)CC1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1-c1nccn1C +CCN(c1cc(-c2ccc(CN3CCOCC3)cc2)cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1Cl)C1CCOCC1 +CC(C)(O)c1cccc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)n1 +CC1=CC(C)(C)Nc2ccc(-c3cc(Br)c(C#N)s3)cc21 +CN(C(=O)OCCOc1ccc2c(c1)CN1CC(=O)NC1=N2)C1CCCCC1 +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(sc5cc(C#N)ccc54)c3=O)CC21 +COCCNc1nc(Nc2ccc(C(=O)N3CCOCC3)cc2OC)ncc1Br +CCC(CC)n1cc(C(=O)NCc2ccc(S(C)(=O)=O)cn2)c(=O)c(-c2cccc(C(F)(F)F)c2)c1C +Nc1ccccc1NC(=O)c1cc2ccc(N3CCNCC3)cc2cn1 +CNC1CCC(N(Cc2cccc(-c3ccncc3)c2)C(=O)c2sc3ccccc3c2Cl)CC1 +c1ccc2sc(Oc3ccc(OCCCN4CCCCC4)cc3)nc2c1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CNCC(O)C(Cc1ccccc1)NC(=O)OCCO 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+COc1ccc(-c2ccc3ncnc(Nc4cccc5[nH]ncc45)c3c2)cc1C=O +c1ccc(CN2CCN(CCCc3ccc(C(c4ccccc4)C45CC6CC(CC(C6)C4)C5)cc3)CC2)cc1 +CCN(CC)CCNC(=O)c1cccc2cc3cccc(I)c3nc12 +CCCCCCCCNC(=O)C(Cc1ccc(OCc2cccc(N)c2)cc1)NC(=O)C1CCC(CN)CC1 +CCCCn1cc(C(=O)c2cccc3ccccc23)c2c(O)cccc21 +NS(=O)(=O)OCC1CC(Nc2cc(NC3CCCc4ccccc43)ncn2)C(O)C1O +Cc1cc(C)c(Oc2cc(Nc3ccc(C#N)cc3)[nH]c(=O)c2)c(C)c1 +Cc1cccc(-c2ccc3c(N4CCOCC4C)nc(N4CC(C)OC(C)C4)nc3n2)c1 +N=C(N)c1ccc(OC(=O)c2ccc(CN3CSCC3C(=O)NC(CC(=O)O)C(=O)O)s2)c(F)c1 +Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NC(C)(C)CO)cn1 +Cc1ccsc1-c1cn(-c2ccc(C(=O)O)c(O)c2)cc1C#N +COc1cc(OCc2cccc(-c3ccc(C(=O)N(C)C)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +O=C1CC(=O)CC(c2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1 +CCCOC(=O)C1(C)CCC2(C)CCC3(C)C4=CC=C5C(=CC(=O)C(O)=C5C)C4(C)CCC3(C)C2C1 +CC(O)(COc1ccc(F)cc1)C(=O)Nc1ccc(F)c(C(F)(F)F)c1 +CCCCc1ccccc1Oc1cccc(CCCC(P(=O)(O)O)S(=O)(=O)O)c1 +COCC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(C(C)(C)C)cc1)C2 +CCCCc1ccc(S(=O)(=O)NC2CCC3C4CCc5cc(O)ccc5C4CCC23C)cc1 +COc1ccccc1-c1cc2c(NC(CO)c3ccccc3)ncnc2s1 +Cn1nc(C(C)(C)C)cc1NC(=O)C(=O)c1ccc(-c2ccc(CN3CCOCC3)nc2)c2ccccc12 +Cc1ccc(NC2=C(N3CCCCC3)C(=O)c3ccccc3C2=O)cc1 +CCN(CC)CCOc1ccccc1CNc1nnnn1-c1cccc(Cl)c1Cl +CC1(O)CCN(c2ccc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)C1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(Cl)cc2)nc2ccccn12 +FC(F)Oc1ccc(-c2ccnc3cc(-c4cccc(Cl)c4)nn23)cc1OCC1CC1 +COc1cc(Nc2nc3n(n2)CCCCC3c2ccc(OCC(F)(F)F)cc2)ccc1-n1cnc(Cl)c1 +O=C(c1ccccc1F)c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12 +COc1cc(OC)c2ncn(CC=C3c4ccccc4COc4ccc(C(=O)O)cc43)c2c1 +COc1cc(C(=O)NC2CC3CC(C)CC(C2)N3)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccccc1)CC2 +NS(=O)(=O)c1ccc(NC(=O)CSc2nnc(C(F)(F)F)n2-c2cccc3ccccc23)c(Cl)c1 +CCC(F)(F)c1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2cccc(F)c2)c1 +O=C(NC1CCN(Cc2cccc(Br)c2)CC1)c1cccc2ccccc12 +CCOc1cccc(-c2cc(C#N)ccc2C#CC(O)(c2ccc(C#N)cc2)c2cncn2C)c1 +COc1cc(OC)cc(N(CCCNC(=O)C(F)(F)F)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1 +CC1CN(Cc2ccccc2)c2ccccc2C(C)N1C(=O)Nc1cccnc1 +NC1CC2CCC(C1)N2C(=O)C(Cc1ccc(Cl)cc1Cl)NC(=O)C1(c2ccc(Cl)cc2Cl)CC1 +Cc1cccc(-n2ncc3c(N(C)C4CCCCC4)ncnc32)c1 +OC(CN1CCC(c2ccccc2)CC1)c1ccc(Br)cc1 +CC(C)C(=O)Nc1ncc(SCc2ncc(C(C)(C)C)o2)s1 +CN1CCN(c2cnc3cc(C(F)(F)F)cc(OCc4cccc([N+](=O)[O-])c4)c3n2)CC1 +CC(Nc1cc(-c2ccoc2)nc(-n2cnc3ccncc32)n1)c1ccccc1 +COc1cc(CN2CCOCC2)ccc1NC(=O)Nc1cnc(C#N)cn1 +CCNC(=O)c1cnn(-c2nc(NC)c3ncn(C4OC(CO)C(O)C4O)c3n2)c1 +CCCCN(C)C(=O)Cc1c(-c2ccc(Cl)c([N+](=O)[O-])c2)nc2c(Cl)cccn12 +O=C(NC1Cc2ccccc2N(Cc2n[nH]c(-c3ncc[nH]3)n2)C1=O)c1cc2cc(Cl)ccc2[nH]1 +O=C1N(CCO)CN(c2ccccc2)C12CCN(C1CCc3cccc(Cl)c3C1)CC2 +CCCN(CCC)Cc1ccc(-c2ccc(CCN3CCCCC3)cc2)cc1 +CC(=NOCCO)c1ccc2nnc(C(C)c3cc4cccnc4cc3F)n2n1 +CC1Oc2nc(cnc2N)-c2c(nc3ccc(C#N)cn23)CN(C)C(=O)c2ccc(F)cc21 +COC(=O)c1cccc2c3cc(-c4ccccc4)n(CC(=O)NC(C(=O)C(F)(F)F)C(C)C)c(O)c-3nc12 +O=C(O)CCCCON=C(c1ccccc1)C(Cc1ccc(Cl)cc1)n1ccnc1 +NC(=NC(=O)CCCCCCCCCCCCCCC(=O)N=C(N)NCCCc1c[nH]cn1)NCCCc1c[nH]cn1 +CC(C)(C)OC(=O)NCCCC(=O)Nc1ccc(S(N)(=O)=O)cc1 +C#CC(C)(C)N1CCN(c2cc3c(cc2C(C)=O)C(=O)c2c([nH]c4cc(C#N)ccc24)C3(C)C)CC1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(Oc2ccccc2)cc1)Cc1cccc(CCCC(=O)O)c1 +CC(NC(=O)Nc1cc2[nH]nc(NC(=O)Cc3ccc(F)cc3)c2cn1)c1ccccc1 +CC(C)Oc1ccccc1N1CCN(Cc2ccc(C(=O)N3CCCCCC3)s2)CC1 +COc1ccc2c(c1NC(=O)C(C)(C)CCCCCCOc1ccc(Cl)cc1)C(=O)CCO2 +CCOC(=O)C1CCN(C(=N)c2ccc(C(=O)Nc3c(OC)cc(Cl)cc3C(=O)Nc3ccc(Cl)cn3)c(F)c2)CC1 +Cc1ccc2nc(Cc3nc(N4CCOCC4)cc(=O)[nH]3)oc2c1 +CCN(Cc1cc(NS(=O)(=O)c2ccc(Cl)cc2)ccc1-c1cc(CC(=O)O)ccc1OC)C(=O)OCc1ccccc1 +N#Cc1cccc(C23CCC(N(CCN4CCC(O)C4)C(=O)Nc4cccc(Br)c4)CC2C3)c1 +COc1ccc(Nc2c3c(nc(N)n4nc(-c5ccco5)nc34)nn2C)cc1 +CCN1C(=Cc2sc3ccccc3[n+]2CC)C=Cc2ccccc21 +CS(=O)(=O)N(CC(=O)N1CCCC(c2ccccc2)C1CN1CCCC1)c1ccc(Cl)c(Cl)c1 +COc1cccc2c1CCCC2CN(C)CCc1ccc2ocnc2c1 +CCCc1cnc(N2CCC(n3nnc4c(Nc5ccc(S(C)(=O)=O)cc5F)ncnc43)CC2)nc1 +Cc1c(NS(=O)(=O)c2ccc(CCCCC3CCNCC3)cc2)c(CC(C)C)nn1C +O=C(CCN1CC2CC(C1)c1cccc(=O)n1C2)c1ccc(F)cc1 +CCCCNc1cc(-c2oc3ccccc3c(=O)c2-c2ccc(F)cc2)ccn1 +OCCCn1cnc2ccc(-c3c(-c4ccccn4)nn4c3CCC4)cc21 +COc1ccc2c(CN3CCC4(CC3)CN(c3ccc(C(=O)O)cc3)C(=O)O4)cn(-c3ccccc3)c2c1 +CN(C)CCc1cccc(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)c1 +COc1ccc(C(=O)N(CCC2CCCN2C)CC(C)=Cc2ccc(F)cc2)cc1OC +COc1cc(S(=O)(=O)c2ccc(C3CCOC3)cc2)cc2c3c(oc12)CCNC3 +O=C1NC(=O)C2(CCN(c3nc4ccccc4n(C4CC5CCC(C4)N5C4CCCCCCC4)c3=O)CC2)N1 +Cc1nc(-c2ccc(OCCNCC(O)c3cccnc3)cc2)c(C)o1 +O=C(O)C1CN(c2nc(NC3CCCNC3)c(-c3nc4ccccc4s3)c(=O)[nH]2)CCO1 +CN(C)C1CCC2(Cc3ccccc3Cc3ccccc32)C1 +CC(OCc1ccc(-c2ccccc2)cc1)(C(=O)NO)C(O)c1ccccn1 +NS(=O)(=O)c1cc(S(N)(=O)=O)c(NC(=O)CN(CCN(CC(=O)O)c2ccccc2O)c2ccccc2O)cc1Cl +O=C(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1cccc2ccccc12 +O=C1c2ccccc2NC12CC13CCN(CC4CC4)C(Cc4ccc(O)cc41)C3(O)C2 +C=CC(=O)Nc1cccc(CNc2nc(Nc3cnn(CCOCC)c3)ncc2Cl)c1 +Cc1cc(CC(NC(=O)N2CCC(c3cccc(Cl)c3)CC2)C(=O)N2CCC(N3CCCCC3)CC2)cc2cn[nH]c12 +COC(=O)c1cc(S(N)(=O)=O)ccc1S(=O)(=O)CCCO +CCCC1CCC(N2CCC(N3C(=O)NC4CCCCC43)CC2)CC1 +CCCCC(C=NNC(=O)N1CCc2ccccc21)NC(=O)OC1(Cc2ccccc2)CCCC1 +O=C(c1ccccc1)c1cnc2c(C(F)(F)F)cccc2c1-c1cccc(NCc2ccc(C(F)(F)C(=O)O)cc2)c1 +Cc1ccc2c(c1)-c1nc(N)nc(-c3ccc(C)o3)c1C2 +O=S(=O)(c1ccc2c(c1)C1CNCC2C1)N1CC1 +CC(Nc1cc(F)ccc1Cl)c1cc(C(=O)N(C)C)cc2c(=O)cc(N3CCOCC3)oc12 +COc1ccc(C(c2ccccc2)c2c[nH]c3ccccc23)cc1 +COc1ccc(C)cc1CN1CCCC(C(=O)N(Cc2cc(Cl)c3c(c2)OCCCO3)CC(C)C)C1 +Cn1cc(-c2cc(C(=O)N3CCCC3CO)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +CCC(C)(C)NC(=O)C1CCN(Cc2cccc(NC(=O)c3cc(C)c[n+]([O-])c3)c2)CC1 +CCc1cc2c(cc1N1CCN(C(=O)C3CCCCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +O=C(NC1CCC(CNCc2cc(-c3ccccc3)on2)CC1)c1cc(C(F)(F)F)ccc1Cl +Cc1[nH]c2ccc(OC3CCN(C(C)C)CC3)cc2c1C(=O)N1CCOCC1 +CNC1CCC(c2ccc(Cl)c(Cl)c2)c2ccc(CC(N)=O)cc21 +CN1C(=CC=Cc2oc3ccc(Cl)cc3[n+]2C)Sc2ccccc21 +Fc1ccc(Nc2nc(Nc3ccc4[nH]cnc4c3)ncc2Br)cc1 +c1ccc(CCc2ccc(C3=C(Cc4ccccc4)c4ccccc4C4=NCCCN43)cc2)cc1 +O=c1[nH]c2ccc(Cl)cc2c(=O)n1CCCCn1ccnc1 +CCC1(CCCCN2CCN(c3ccc(OC)cc3)CC2)C(=O)Nc2ccccc21 +O=C(OC1C2CC3CC(C2)CC1C3)N1CCCC1c1nc(-c2ccncc2)cs1 +NC(=O)C1Cc2ccccc2CN1C(=O)CC(N)Cc1ccccc1F +O=C(c1c(F)cccc1F)N1CCc2c(cnn2-c2ccc(F)cc2Cl)C1 +COc1cc2c(cc1OC)-c1n[nH]c(-c3ccc(Br)nc3)c1C2 +Nc1nc(O)c2ncn(-c3cccc(C(F)(F)F)c3)c2n1 +CNC(=O)c1ccc(NC(=O)c2cc3c(C)nn(C4CCCCC4)c3s2)cc1 +O=C(Nc1ccc(C(=O)N2Cc3ccccc3C2)cc1)N1Cc2ccccc2C1 +CC1CCC(c2ccccc2)S(=O)(=O)N1Cc1ccc(N2CCC(CO)(n3cnnc3)CC2)cc1F +COc1ccc(-n2nc(C3CCN(S(=O)(=O)C4CC4)CC3)cc2NC(=O)c2cnn3cccnc23)c(F)c1 +CCCCN1CCC(C(=O)NO)(S(=O)(=O)c2ccc(OC)cc2)CC1 +Nc1nc(N)c2c(OCC3CCN(S(=O)(=O)c4cccc5ccccc45)CC3)cccc2n1 +CCCCCCCCC(=O)N(CC(C)C(=Nc1ccccc1)Nc1ccccc1)c1ccccc1 +CN1CCN(c2ccc(-c3ccc4[nH]c5nccc(Nc6ccccc6[N+](=O)[O-])c5c4c3)cc2)CC1 +CN1C(=O)C(c2cccc(-c3cccnc3)c2)(c2ccc3c(c2)OCO3)N=C1N +CC(C)c1cccc(-n2nc(C#N)c(=O)n(CCCN3CCCCC3)c2=O)c1 +O=C1NC(=O)C(c2ccc(Oc3ccccc3)cc2)(N2CCCN(C(=O)N3CCOCC3)CC2)C(=O)N1 +CC1(C)c2n[nH]c(Nc3nccc(C(F)(F)F)n3)c2CN1C(=O)NC1CC1c1ccccc1 +O=C(CN(c1ccc(Br)cc1)S(=O)(=O)c1ccc(Cl)c([N+](=O)[O-])c1)NCCc1ccccc1 +CCc1csc(C(Cc2ccc(NS(=O)(=O)O)cc2)NC(=O)C(Cc2ccccc2)NC(=O)CC(=O)OC)n1 +NC(=O)C(=O)N1CCCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +NS(=O)(=O)N1CC(C(=O)Nc2ccc(Cl)cc2)C(C(=O)Nc2ccc(-n3ccccc3=O)cc2F)C1 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)cc2Cl)NC(CCN2CCCCC2)C1=O)c1ccccc1 +O=C(CCCCCNC(=O)NC1CCCCC1)NC(Cc1ccccc1)C(=O)N1CCCC1C(=O)O +O=C1NC(NCC23CC4CC(CC(C4)C2)C3)=NC1=Cc1c[nH]c2ncccc12 +O=C(O)c1cc2cc(O)c(O)cc2c(C(=O)c2ccc3ccccc3c2)n1 +Cc1cc(Cl)ccc1-c1cc(COc2ccc(C(CC(=O)O)c3nccn3C)cc2)ccc1C +CCOC1CN(c2ccc(Nc3nnc4cc(-c5c(C)cccc5C)cc(C)c4n3)cc2)CCO1 +CN1c2ccccc2C(NCCCCCCC(=O)NCCCCCNc2c3c(nc4ccccc24)CCCC3)c2ccc(Cl)cc2S1(=O)=O +Cn1nc(-c2ccccc2)cc1-c1ccc(C(=O)Nc2ncccc2F)s1 +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1ccc2cc(Oc3ccc(C(F)(F)F)cn3)ccc2n1 +COc1ccc2[nH]nc(NC3CCN(Cc4ccc5c(c4)OCO5)CC3)c2c1 +COC(=O)C1CCC(Nc2cnc3cc(OC)c(OC)cc3n2)CC1 +CCCCCCC[n+]1c(C=Cc2ccc(N(CC)CC)cc2)sc2ccccc21 +O=C(Nc1cc(OC2CCOC2)cc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1 +COc1ccc(CNC2(c3nc(-c4ccc(C)cc4)c[nH]3)CCCC2)cc1 +COc1ccc2c(c1)c(C(=O)C=C(O)C(=O)O)cn2Cc1c(C)cc(C)cc1C +CCCN(c1ccccc1Br)S(=O)(=O)c1ccc(O)cc1 +CN(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(=O)C1CN(C(=O)C2CCCCC2)CC1c1ccccc1 +CCC(CC)CN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +CCCCCNC=C1C(=O)CCC2(C)C1=C(O)C(=O)c1cc3c(cc12)C(=O)C=CC3=O +CC(C)C(=O)N1CCN(C(=O)c2cc(Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)CC1 +Cc1cc(S(=O)(=O)N2C=CNC(=O)C2CC(=O)N2CCCCC(N(C)C)CC2)c(C)cc1Cl +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)c1ccccc1N1CCCCC1 +Cc1noc(-c2ccccc2C(=O)N2C3CCC2C(COc2cccc(C(F)(F)F)n2)C3)n1 +Cc1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(-c3ccc(F)cc3F)no2)n1 +O=c1[nH]c(NCCO)nc(NC2CCCNC2)c1-c1nc2ccccc2s1 +COC(=O)CCCCCCCCOC(=O)C=CCC1OCC(NS(=O)(=O)CCCCl)C(O)C1O +O=C(CCCN1CCN(Cc2ccc(F)cc2)CC1)NC1c2ccccc2SCC2CCCCC21 +CC1CCN(c2cnc3c(c2)C(O)c2cccc(C#N)c2C=C3)CC1 +Cc1c(OCCCCCN2CCCCC2C)ccc2c(=O)cc(-c3ccccc3)oc12 +COc1ccc(-c2cc3c(N)cccc3c(=O)[nH]2)cc1 +OCCOc1cc(CC2CCN(CCc3ccc4c(c3)C(O)CCO4)CC2)ccc1Br +COc1cc(N2CCNCC2)ccc1Nc1nc(N2CCCC2)n2ccnc2c1C(N)=O +CCCn1c(=O)n(C)c(=O)c2[nH]c(-c3ccccc3)nc21 +CC(=O)OC1CC2C3(C)COC(c4ccccc4)OC3CCC2(C)C2C(O)c3c(cc(-c4cccnc4)oc3=O)OC12C +O=C1Nc2cccc3c2C1(CCCCN1CCN(c2ccccc2Cl)CC1)CCC3 +CC(C)C(NC(=O)Cn1c(-c2ccc(F)cc2)ncc(NC(=O)OCc2ccccn2)c1=O)C(=O)C(F)(F)F +Cc1sc(NC(=O)c2ccc(Nc3ccncn3)cc2)nc1-c1ccc(F)c(C(F)(F)F)c1 +N#Cc1ccc(Cn2cncc2CNC2CCN(c3ccccc3)C2=O)cc1 +CC(=CCOP(=O)(O)OP(=O)(O)O)CCC=C(C)COC(=O)C(=[N+]=[N-])C(F)(F)F +CCOc1ccc(Br)cc1-c1cc2nc(N)nc(N)c2cc1C +COc1ccc2c(C)cc(NC3CCCC(NCc4cccc5nsnc45)C3)nc2c1 +NC(=O)CNCC1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +O=C(c1cc(-c2ccccc2O)on1)N1N=C(c2cccnc2)CC1c1ccccc1O +CN(C)C1CCCC1Nc1nc(Nc2ccc([S+](C)(=N)[O-])cc2)ncc1C(F)(F)F +COc1cccc2c(C(=O)NCc3cccc(C4CCC4)n3)nc(N)nc12 +Cc1ccc2c(c1)c(C#N)cn2-c1nc(C)c(C(=O)O)s1 +O=S(=O)(c1cccnc1)c1sc2ncccc2c1-c1ccc(Cl)cc1 +Cc1nc(NC(=O)c2cc(Cl)cc(Oc3cncnc3)c2)ccc1F +Cc1ccc(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1NC(=O)NCC1CCN(C)CC1 +COCCOc1ccc2c(OCCn3c(=O)oc4cc(C)ccc43)ccnc2c1 +COc1cnc(-c2cc(Cl)ccc2F)nc1Nc1ccncc1C(=O)NCCNCCO +CC(C)C1CC(C(=O)Nc2ncc(SCc3ncc(C(C)(C)C)o3)s2)CCN1 +O=[N+]([O-])c1cc2nc(O)c(O)nc2cc1CN1CCCCC1 +COc1cccc(-c2cc(=O)c3cc(Cl)cc(NCCC(O)CO)c3o2)c1N +CC(=O)C1CCC2C3CCC4CC(O)(C(F)(F)F)CCC4(C)C3CCC12C +COc1cccc(Nc2cc(-c3cccc(-c4cc(C(=O)O)ccc4O)c3)nc3c2C(=O)NCC3)c1 +C=C(C)C(O)C1OC2SC(N(C)C)=NC2C(O)C1O +COc1cc(Nc2ncc(F)c(Nc3ccc4c(c3)OCCO4)n2)cc(OC)c1 +CC1CCCN1C1CCN(c2ccc(N3CCCC4(CCN(C(=O)OC(C)(C)C)CC4)C3=O)cc2)C1 +CC(C#Cc1ccc(Cl)cc1)=CCON=C1CN2CCC1C2 +COc1cc(-c2cn(C)c(=O)c3ccccc23)cc(OC)c1CN(C)C +O=C(C1CCCN(c2ccc3nc(Cc4ccc(Cl)cc4)[nH]c3n2)C1)N1CCCC1 +COc1ccc2c(c1OCc1ccccc1)CC(C(=O)O)N(C(=O)Nc1ccc(F)cc1)C2 +CC(C)Nc1ncc2c(n1)CN(C(=O)NC(CCC#N)c1ccc(Cl)c(Cl)c1)CC2 +COC(C)(c1ccc(F)cc1)c1ccc(C(=O)N(C)CCCCCCC(=O)NO)cc1 +O=C1C(=Cc2ccc(O)c(Br)c2)OC(=S)N1c1ccc(C(F)(F)F)cc1 +CCC(COC)N1CCc2cn(-c3ccc(Cl)cc3C#N)c3nc(C)cc1c23 +CCOC(=O)C1CCC(N(CC)c2cc(Cl)cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c2C)CC1 +CC(C)(C)NCC1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 +COc1ccc(C(=O)Nc2ccc(OC)c(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N3CCCC3)nc12 +Cc1cc(Nc2nc(Sc3ccc(NC(=O)C4CC4)cc3)nn3cc(NC(=O)CCN4CCCCC4)cc23)n[nH]1 +N#Cc1cc(S(=O)(=O)Nc2ncc(F)s2)ccc1Oc1ccc(Cl)c(Cn2cccn2)c1 +CCN(CC)CCCC(C)Nc1cc(-c2ccc(C(F)(F)F)cc2)c(C#N)c2nc3ccccc3n12 +CC1(CC=C2CCC2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C(O)c2ccccc21 +CC(NC1CC1)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +COC(=O)CCCc1onc(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1Sc1cccc(OC)c1 +Nc1ncc2ccc(-c3ccc(NC(=S)Nc4cc(C(F)(F)F)cc(C(F)(F)F)c4)cc3)cc2n1 +CCn1c2c(c(=O)[nH]c1=O)C(c1ccc(C)cc1)C1=C(COC1=O)N2 +O=C(c1ccc(-c2ncccn2)cc1)N1CCC(c2nc3ccccc3[nH]2)CC1 +CN1CCN(c2cc(Nc3cc(C4CC4)[nH]n3)nc(NCc3cc(-c4nccs4)no3)n2)CC1 +Cc1ccc(S(=O)(=O)N2CCC(c3cc(CC(=O)O)cc4ccc(F)cc34)CC2)cc1 +NC(=NC(=O)c1ccc(CC(N)C(=O)O)cc1)NCc1ccccc1N1CCC(c2ccccc2)CC1 +O=C(OC1C[N+]2(CC=Cc3ccccc3)CCC1CC2)C(O)(c1ccccc1)c1ccco1 +Nc1ncnc2c(CN3CC(O)C(CSCc4ccccc4)C3)n[nH]c12 +CCc1cc(CC)n2nc(-c3ccc(OC)cc3)c(CC(=O)N3CCCC3)c2n1 +COc1cc(Br)c(CC(=O)NC(=N)NC(CC(C)C)C(=O)NCc2cccc(-c3nnn[nH]3)c2)cc1OC +COc1cccc(-c2cc(C(N)=O)c3[nH]c4cc(C(=O)N5CCN(C(=O)C6CC6)CC5)ccc4c3c2)c1 +CC(C)Oc1ccccc1N1CCN(Cc2ccc(CN3CCCCC3=O)[nH]2)CC1 +O=C(NCCN1CCOCC1)c1ccc2[nH]c3c4c(c5c(c3c2c1)CNC5=O)CCC4 +Cc1c(S(=O)(=O)NCCCCN2CCC(c3noc4cc(F)ccc34)CC2)sc2ccc(Cl)cc12 +Nc1n[nH]c2cc(-c3nc(C(Cc4ccccc4)NC(=O)c4ccc5c(N)noc5c4)[nH]c3Cl)ccc12 +Cc1cnc(NC(=O)C(c2ccc(Cl)cc2)C(C)C)s1 +CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2Cc2csc(N)n2)n1Cc1ccc(C(=O)O)cc1 +CC(N)C1OC(OC2C(O)C(NC(=O)C(O)CCN)CC(N)C2OC2OC(C(C)O)C(O)C(O)C2N)C(O)C1O +COC(=O)Nc1nc2cc(C(=O)c3cc(CNC(=O)OC(C)(C)C)cs3)ccc2[nH]1 +CCCc1cc(-c2ccc(OC(F)(F)F)c(C(F)(F)F)c2)nc(C#N)n1 +CC1C(=O)NC(Cc2ccc(F)cc2)C(=O)NCC#Cc2ccccc2OCCNC(C2CC2)C(=O)N1C +CC(C)(C)CC(=O)N1CCN(C(c2ccc(Cl)cc2)c2cncnc2)CC1 +Cc1ccc(C(C)NC(=O)COc2cc(C(F)(F)F)c3c(C4CC4)nn(C)c3n2)cc1 +O=Nc1c(-c2c(O)[nH]c3cc(Cl)c(Cl)cc23)[nH]c2ccccc12 +COc1cccc(CO)c1-c1cc(C(CC(=O)O)c2nnc(C)o2)cc(C(F)(F)F)c1 +O=C(CCCCCCNC(=O)c1ccc(C(O)(c2ccccc2)c2ccncc2)cc1)NO +O=C(O)c1cc(-c2ccsc2)c2ccc(OCc3c(Cl)cncc3Cl)cc2c1 +N=C(N)NCCCC(NS(=O)(=O)Cc1ccccc1)C(=O)N1CCCC1C(=O)NCc1ccc(C(=N)N)cc1 +COc1cc(-c2ccc3c(-c4ccc5ccccc5c4)n[nH]c3c2)ccc1O +NS(=O)(=O)c1c(F)c(F)c(S(=O)(=O)CCO)c(NC2CCCCCCC2)c1F +CCN(CCN(C)C)C(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +Nc1nc(-c2ccco2)c2nnn(Cc3cccc(C(F)(F)F)c3)c2n1 +CC(O)C(=O)N1CCC(CCn2c(Sc3cc4c(cc3Br)CCO4)nc3c(N)ncnc32)CC1 +O=C(NCCCCc1ccccc1)n1c(=O)oc2c(Br)cccc21 +COc1nc(-c2ccccc2Cl)cc2nc(-c3c(Cl)c(C(C)(C)CF)nn3C)[nH]c12 +CC1=NC(C)Cc2c(-c3ccc(C(F)(F)F)cc3)ccc(O)c21 +O=C1N=c2cccc(OCC(O)CNC3CCN(c4ccc(CC5SC(=O)NC5=O)cc4)CC3)c2=N1 +Nc1cccc(CCOc2ccc(CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)n1 +O=C(O)COc1ccc(Br)cc1C=NNc1cccc2cccnc12 +CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccccc21)C(=O)C1CC1 +Cc1ccc2c(N3CCN(CCc4cccc(NC(=O)c5ccccc5)c4)CC3)cccc2n1 +COc1ccc(CNc2cc(OCc3ccccn3)ccc2C(=O)c2cc(OC)c(OC)c(OC)c2)cc1Cl +CCCc1c(OCCCCOc2ccc(-c3nn[nH]n3)cc2)ccc2c1cc(C)n2CC(C)(C)C +O=C(Cc1cccc(C(F)(F)F)c1)NC(Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1 +CN1CCC(c2nc(-c3ccc(F)cc3)c(-c3ccncc3)s2)CC1 +CCC(O)CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +Cc1cc(-c2cc(-c3ccccc3Cl)[nH]c(=O)n2)ccc1O +Cn1ncc2c(c1=O)OCCCN2C(=O)CCNCCOc1cccc(Cl)c1 +O=C1OCc2c1cc1cc(OCc3cccc(C4(O)CCOCC4)c3)ccc1c2-c1cccnc1 +O=c1c2c([nH]c3ccc(-c4ccc(C(F)(F)F)cc4)cc13)CCSC2 +CCCCCCC1(c2cc(O)c3c(c2)OC(C)(C)C2CC=C(C)CC32)Sc2ccccc2S1 +NS(=O)(=O)c1ccc(NC(=O)N2CCN(c3ccc(C(F)(F)F)cn3)CC2)cc1 +NC(=O)Nc1ccc2ncnc(Nc3ccc(F)c(Cl)c3)c2c1 +Cc1ccc(NC(=O)c2ccc(Cl)cn2)cc1C1(C(F)F)N=C(N)OC2CC21 +CCC(CO)N1C(C)=CC(=Cc2sc3ccccc3[n+]2Cc2ccccc2)C=C1C +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1(C)CCN(C(=O)C(N)C3CC3)C1)CC2 +CN1CCCCC1COc1cc(NC(=O)N2CCCc3cc(CO)c(C=O)nc32)ncc1C#N +CCCCCCCCCC(=O)Nc1ccn(C2COC(CO)O2)c(=O)n1 +Nc1ccccc1C(=O)CCCN1CCC2C(C1)c1cccc3c1N2CCC3 +Cc1cncc(-c2cc3c(-c4cccc(N5CCCNCC5)n4)n[nH]c3cn2)n1 +O=C(NC1CCCc2c1[nH]c1ccc(Br)cc21)c1ccccc1F +CC1=C2c3ccc(O)cc3CC2(c2ccccc2)CCC1=O +O=S(=O)(Nc1ncns1)c1ccc2c(-c3ccccc3Cl)cccc2c1 +NC(=O)C(c1ccccc1)(c1ccc(F)cc1)c1ccccc1F +O=C1OC(=O)c2c1[nH]cc1nc3ccccc3c2-1 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+S=C(NCc1ccccc1)N1CCC(c2c[nH]cn2)CC1 +CC(C)c1cc(C(C)C)c(S(=O)(=O)NCC2CCC(C(=O)NNC(=O)c3cccs3)CC2)c(C(C)C)c1 +Cc1ccc2c(NC3CC3)noc2c1-c1ccc2c(c1)NC(=O)C21CCCC1 +COc1cccc2c3c([nH]c12)CCN(C(=O)C1CCCCC1C(=O)NC1(C#N)CC1)C3 +CC(C)(C)c1nc(CCCCCC#N)c2c(N)c(C#N)c(N)nc2n1 +NC(=S)c1cn(OC2OC(CO)C(O)C2O)c2ncnc(N)c12 +CN1CCN(c2ccc(C(=O)Nc3n[nH]c4cc(OC5CCN(Cc6ccccc6)CC5)ccc34)cc2)CC1 +COc1ccc2c(n1)CCN(C(=O)C1CC(C(=O)O)C1)C2C(=O)Nc1cc(F)c2c(c1)CCC2(C)C +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(=O)NC3CCOCC3)c12 +CC(C)C(CC(=O)N1CCc2ccccc2C1)NCC(=O)N1CCCC1C#N +O=C(NC1C2CC3CC1CC(O)(C3)C2)c1cnc(NCCO)nc1OC1CCC1 +O=C(O)c1ccc2c(c1)nc(-c1ccc(OCc3cc(N4CCCC4=O)ccc3N3CCCCC3)cc1F)n2C1CCCCC1 +CCc1ccc(C#Cc2c3n(c4ncnc(N)c24)C(C)CC3)cc1 +CCc1c[nH]c2ncnc(N3CCC(N)(CNC(=O)c4ccc(F)cc4F)C3)c12 +CCCCCOc1ccc(C(=O)NCCc2ccc(O)cc2)cc1OCCCCC +CCCn1c(=O)c2[nH]c(Cc3ccco3)nc2n(Cc2ccco2)c1=O +CCCc1cc(C2CCOCC2)ccc1OCCCOc1cccc(C2OC(=O)NC2=O)c1 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCCC2)CCN(C2CCCCCC2)C1 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+COCCOC1CCC(n2nc(-c3ccc(Nc4nc5cc(C)cc(C)c5o4)cc3)c3c(N)ncnc32)CC1 +O=C1CCCN1C(=O)C1CC2CCCCC2N1C(=O)C1CC1c1ccccc1 +Cc1cc(SC2=C(O)OC(CCc3nccs3)(C(C)C)CC2=O)c(C(C)(C)C)cc1CO +C=CC(=O)N1CCC(N2C(=O)N(Cc3ccccc3)Cc3cnc(Nc4ccc(N5CCN(C)CC5)cc4OC)nc32)CC1 +CC(c1ccc(COCc2ccccc2)o1)N(O)C(N)=O +N#CC1CC(F)(F)CN1C(=O)CNC(=O)c1ccccc1 +CCN(CC(=O)NCC1CCCN(c2ccc(C(F)(F)F)cc2)C1)S(=O)(=O)c1ccc(F)cc1 +O=C(CCN1CCN(c2ccc(Cl)cc2)CC1)c1ccccc1 +OCC1C(O)C(O)C(O)CN1CCCCCCOC1CCCCC1C1CCCCC1 +CNC(=O)c1c(C(N)=O)nn2c1CCOc1ccc(C#CC3(O)CCN(C)C3=O)cc1-2 +O=C(O)CC(Cc1nc(CCCCNc2cc(N3CCOCC3)ccn2)no1)c1ccc2c(c1)OCO2 +C=CCN1CC(C)N(C(c2ccc(C(=O)N3CCCCC3)cc2)c2cccc(OC)c2)CC1C +N#CC(Cc1ccc(-c2ccc3c(c2)NC(=O)CC3)cc1)NC(=O)C1NC2CCC1C2 +CC1OC(n2cnc3c(NCc4ccc([N+](=O)[O-])cc4)ncnc32)C(O)C1O +N#Cc1cnccc1COc1cnc(N2CC3CCC(C2)N3C(=O)OCC(F)(F)F)nc1 +Cn1c(N(CCCCN)CCc2ccccc2)nc(-c2ccncc2)cc1=O +COc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C1NC(=O)OC1C +COc1ccc(OC2CCN(c3nc4c(nc3NC(C)C)CCN(C)C4)CC2)c(F)c1 +CC(C(=O)NCc1ccc(C(F)(F)Cl)nc1SC1CCCCC1)c1ccc(NS(C)(=O)=O)c(F)c1 +O=S1(=O)CCC(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nc2)CC1 +COCCn1cc(-c2ccc3cnc(Nc4ccc(-c5cnc(C)n5C)cc4OC)cc3c2)cn1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCCc1ccc(I)cc1 +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN(C)C1CCNC1=O +O=C1C(NC2CCCC2)=C(N2CCOCC2)C(=O)c2ccccc21 +O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c2ccccc12 +CCCCCCSc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +CC1CC(COC(C)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)(c2ccccc2)NC1=O +COc1cc(CC2NCCc3cc(O)c(O)cc32)ccc1O +Cc1cc(-c2nc(-c3ccc(F)c(Cl)c3)n3c2CCOC(CF)C3)cc(C)n1 +CC(C)(C)c1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2CCC2CCCCC2)c1 +CCCCCn1cc(C(=O)c2ccc(CCCC)c3ccccc23)c2ccccc21 +O=C(c1ccccc1NCc1ccc2[nH]ncc2c1)c1n[nH]c2ccccc12 +CCn1c2ccccc2c2cc(Nc3cc(C)nc4ncnn34)ccc21 +N=C(N)N1CCCC(NC(=O)CN2C(=O)C(NS(=O)(=O)Cc3ccccc3)Cc3ccccc32)C1O +COCc1ccc(C(C)=O)c2sc(C(=O)Nc3cc(CN4CCNCC4)c4ccccc4n3)c(C)c12 +CCCCCCCc1nc2c3cn[nH]c3[nH]c(=O)n2n1 +Cc1ccccc1Oc1ccc([N+](=O)[O-])cc1S(=O)(=O)NC(=O)NC(C)(C)C +O=C(NC1CCN(Cc2ccccc2)CC1)c1ccc2ccccc2c1 +Cc1ncnc(C#N)c1-c1ccc(Oc2nccc3[nH]ccc23)cc1F +O=c1c(-c2cccc(Br)c2)nc2ccccc2n1Cc1ccccc1 +Cc1nnc2c(Nc3cccc(CNC(=O)c4ccccc4)c3)nc3ccccc3n12 +COc1cccc(NC(=O)Nc2ccc(-c3cc4ccccc4n3C(N)=O)cc2)c1 +Cc1c(C(=O)OCC(C)C)[nH]c2c1C(=O)CC(c1ccco1)C2 +c1cc(C2CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)ccc1OCCN1CCNCC1 +CCN(CC)CCCOc1ccc2c(Nc3ccc(NC(=O)NC4CCCCC4)cc3)ncnc2c1 +CN(C(=O)Cn1c(=O)oc2ccc(-c3ccc(OC(F)(F)F)cc3)cc21)c1cccnc1 +CCC(NC(=O)C1CC(S(=O)(=O)c2ccc(-n3cccn3)cc2)CN1C(C)=O)C(=O)c1nc2ccccc2o1 +CCCOCCOC(=O)c1c(C)nc2sc(C(=O)c3ccc(OC)cc3)c(N)c2c1-c1cc(OC)c(OC)c(OC)c1 +CC1c2nnn(-c3cnccn3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl +CC(C)CC(NC(CCN1C(=O)c2cc3ccccc3cc2C1=O)C(=O)O)C(=O)NC(C)c1ccccc1 +CCc1cccc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(C)c34)cc2)c1 +CN1CCN(c2cccc3[nH]c(-c4n[nH]c5cc(-c6ccc(CO)cc6)ccc45)nc23)CC1 +Nc1nc2c(cnn2CCN2CCOCC2)c2nn(Cc3ccccc3)c(=O)n12 +O=C(Cn1nc(-c2ccccc2)cc1-c1ccccc1)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +COc1ccc(C=NNC(=O)C(Cc2c[nH]cn2)NC(=O)c2ccc(OC)cc2)cc1 +N#Cc1c(N)nc(SCc2c[nH]cn2)nc1-c1ccc2c(c1)OCO2 +CC(C)Oc1ccc(S(=O)(=O)N2CCN(c3ccc(C(=O)Nc4cnco4)c(OCC(=O)O)c3)CC2)cn1 +COc1cc(C=CC(=O)NO)ccc1OCC(Cc1c[nH]c2ccccc12)NC(=O)c1ccccc1Cl +COc1cc(-c2cnc(C)n2C)cnc1Nc1cc2cc(-c3cnn(CC(C)(C)O)c3)ccc2cn1 +CCOC(=O)c1cccc(NC(=O)CCCCCCCSc2nnc(Cc3nn(C)c(=O)c4ccccc34)n2C)c1 +Cc1cccc(-c2[nH]c(NCc3cccc(C#N)c3)nc2-c2ccc3c(c2)OCO3)n1 +COCCn1cc(-c2ccc3[nH]nc(-c4cc(N5CC(C)OC(C)C5)ncn4)c3c2)cn1 +Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1Nc1ncnc2cnc(N3CCCOCC3)nc12 +CC(C)COc1cccc(Oc2cc3c(cc2NS(=O)(=O)C2CC2)n(C)c(=O)n3C)c1 +CCOC(=O)C1=NC2(SC1)C(=O)N(C1CCCCC1)c1ccc(Br)cc12 +CCC1COC(c2ccc3c(C(=O)NCc4cncc(F)c4)c(C(C)C)n(Cc4ccccc4)c3c2)=N1 +Cc1cccc2c1NC(=O)C(NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(N)=O)N=C2c1cccc(Cl)c1 +CCOC(=O)C1C(OC(c2ccc(F)cc2)c2ccc(F)cc2)CC2CCC1N2C +c1c(Nc2nc(N3CC4CCC3C4)nc3c2CCC3)n[nH]c1C1CC1 +Cc1[nH]c2ccccc2c1CCN(CCC(F)F)Cc1ccc(C=CC(=O)NO)cc1 +Cc1cc(Nc2nccc(C3CC3)n2)cc(-c2cnc(C3(N)CCC3)s2)c1 +O=S1NC(c2ccc(S(=O)(=O)N(CCC3CC3)c3sc4ccccc4c3Br)cc2)=NO1 +CN(Cc1ccc(Cl)cc1)C(=O)C1CCCN1C(=O)Nc1ccc(C(F)(F)F)cc1 +N#Cc1cnc2c(Br)cc(NCc3cn(CC(=O)O)nn3)cc2c1Nc1ccc(F)c(Cl)c1 +Cn1cc(-c2[nH]c(-c3ccnc(N)n3)cc2C(N)=O)c2ccccc21 +CCN(CCCCCN1C(=O)c2ccc([N+](=O)[O-])cc2C1=O)CCCc1ccccc1 +c1cc2c(ncn3nnc(C4CCC(CNc5ccc(N6CCOCC6)cc5)CC4)c23)[nH]1 +COc1cccc(-c2c3n(c(=O)n(CC(N)c4ccccc4)c2=O)C(c2ccccc2F)CS3)c1Cl +Cc1cc(C)[n+](CC(=O)NCc2ccc(S(N)(=O)=O)cc2)c(C)c1 +CC(=NNC(=N)N)c1c[nH]c2ccc(NS(=O)(=O)c3ccccc3)cc12 +CC1CN(Cc2ccccc2)c2cc(Br)ccc2C(C)N1C(=O)Nc1cccnc1 +Cc1ccc(-n2nc(C)c3cc(CNCc4cccc(C(F)(F)F)c4)c(=O)[nH]c32)cc1 +Nc1nn2cccnc2c1C(=O)Nc1cn(CC(=O)N2CCC(O)C2)nc1-c1cc(Cl)ccc1OC(F)F +CC(=O)N1CCC(NC(=O)NC2CCC(C)(C)CC2)CC1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ncnc(OCC(C)(C)O)c3Cl)C2)cc1 +CN(C(=O)CNC(=O)c1cc2cc(Cl)ccc2[nH]1)C1CCCCC1 +O=C(NO)c1coc(-c2ccc(-c3ccccc3)cc2)n1 +COc1cc(NC(C)CCCN(Cc2ccc(F)cc2)C(=O)C(C)(C)CCl)c2ncccc2c1 +CN1C(=N)NC(C)(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CS1(=O)=O +CN(C)CCc1ccc(C2=CCC3CN(Cc4ccccc4)CC23)cc1 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+CCCOCCn1nc(CC)c2nc(N3CCNCC3)nc(Nc3ccccn3)c21 +CN(CCCC1(c2ccc(F)cc2)OCc2cc(C#N)ccc21)C1CC=C(c2c[nH]c3ccccc23)CC1 +CCN1C(=O)c2c(nc(C(N)=O)n2Cc2ccc(O)c(Br)c2)N2C1=NC1CCCC12 +COC(=O)c1c(Cl)c2n3ccccc3c(C)c(-c3ccccc3)c-2c1C(=O)OC +CC1CN(Cc2ccc(Cl)cc2)CC[N+]1(C)CC(=O)N1CCc2ccccc21 +CC(C)CC1C(=O)NC(C2Cc3ccccc3C2)C(=O)N1C(C(=O)NC(C)C)c1cc(Br)cs1 +CCCCCC(=O)N1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2Cl)CC1 +COc1cc2cc[n+](C)c(CCCCc3c4cc(OC)c(OC)cc4cc[n+]3C)c2cc1OC +CCS(=O)(=O)c1ccc2cc1CNC(=O)C(Nc1ccc3c(N)nccc3c1)c1ccc(cc1)CCCC(=O)N2 +c1ccc(CN2CCC(CCOC(c3ccccc3)c3cccs3)CC2)cc1 +O=C1NC(C(=O)O)Cc2ccc(cc2)OCCCCOc2cccc(Cl)c21 +Cc1cccc(-c2nn(Cc3cccc(C(N)=O)c3)cc2-c2ccc3ncccc3c2)n1 +CC(C)Oc1ccccc1N1CCN(Cc2cc(CN3CCCCC3=O)no2)CC1 +CS(=O)(=O)c1cccc2c(CCNCC(O)c3cccc(NS(=O)(=O)CC(F)(F)F)c3)c[nH]c12 +CC(c1ccccn1)c1c(CCN2CCCC2)sc2ccccc12 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCC3)CC2)c1)c1ccc(F)cc1 +CN(C)C1CCN(c2ccc(-n3ncc4cc(-c5ccc(Cl)cc5)ccc4c3=O)cn2)C1 +O=C(Cc1ccc(Br)cc1)NCCC(c1ccccc1)c1ccccc1 +CCOC(=O)C(C)=CC(C(C)C)N(C)C(=O)C(NC(=O)C(=Cc1ccco1)NC(C)=O)C(C)(C)C +CCCC1(C(O)CC=CC2C(O)CC(=O)C2CCCCCCC(=O)O)CCC1 +Cc1ccccc1-c1c(C(=O)N(C)Cc2ccccc2Cl)n(C)c(=O)c2ccccc12 +COc1ccccc1C1CN=C(c2ccc(OC(F)(F)F)c(Cl)c2)N1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4cnccn4)ncc23)ccn1 +O=C(CO)N1CCC(c2cc3c(-c4cncc(NCc5cccnc5)n4)ccnc3[nH]2)CC1 +O=S(=O)(c1ccc2ccccc2c1)N1CCC(c2nc(-c3ccncc3)no2)CC1 +O=C1c2ccccc2C(=O)c2oc(-c3ccccc3)nc21 +CCOc1cc(F)ccc1NS(=O)(=O)c1ccc2c(c1)CN(C(=O)Nc1ccc(C(C)(C)C)cc1)C2 +Cc1ccn2c(C)c(N(Cc3ccc(F)c(C(F)(F)F)c3)S(=O)(=O)c3ccccc3)nc2c1 +COC1C(C)CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cc(C4(O)CCOCC4)cc3F)n2)CC1N +COc1cc(Cc2cnc(N)nc2N)cc(C#CCCC(=O)O)c1Br +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(OCC2CCCCN2C)n1 +CCC(C)C(N)C(=O)NS(=O)(=O)OCC1OC(c2nc(-c3ccccc3)cs2)C(O)C1O +Cn1c(=O)n(CC2CCC(NC(=O)c3cc(Cl)ccc3Cl)CC2)c2ccccc21 +COc1cc2c(cc1OC)C1C3Cc4cc(OC)c(OC)cc4C(COC(=O)CCCc4ccccc4)N3C(C#N)C(C2)N1C +O=S(=O)(c1ccc(Cl)cc1)N(C1CCNCC1)C1CC1 +NCC1CCCc2cc(S(=O)(=O)c3cc(F)cc4[nH]cnc34)ccc21 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+Cc1cccc(-c2csc(N3CC4CC4(C(=O)O)C3)n2)c1OCc1ccc2c(c1C)CCN(C1CCOCC1)CC2 +Cc1ccsc1C=CC(=O)NC(C)c1nc2scc(C)c2c(=O)o1 +CC(C)Nc1ncc2c(n1)c(NC1CC1)nc1cc(C(=O)O)ccc12 +CC1=CC(C)(C)Nc2cc3c(cc21)-c1cccc(CO)c1C3 +O=S(=O)(c1cccc(F)c1)c1cn(C2CCNC2)c2cc(Cl)ccc12 +NS(=O)(=O)c1ccc(CCN=Cc2cccc(Br)c2O)cc1 +CC(NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)c(F)c1)c1ccccc1 +COc1cc(C(=O)c2sc(Nc3ccc(Cl)cc3)nc2N)cc(OC)c1OC +O=[N+]([O-])C=Cc1cccc(OCc2ccc(C(F)(F)F)cc2)c1 +COc1cc(Sc2c[nH]c3ccc(Br)cc23)cc(O)c1OC +CC(NC(=O)c1cccc2c1N(Cc1ccc(C(F)(F)F)cc1)CC2)c1ccc(-c2nn[nH]n2)cc1 +c1ccc(-c2nc(NCCCn3ccnc3)cc(-c3ccncc3)n2)cc1 +COc1ccccc1N1CCN(CCC(O)c2csc3ccccc23)CC1 +O=C(NC1CCNCC1)c1c[nH]nc1NC(=O)c1c(Cl)cccc1Cl +COc1cccc2cc(-c3cc(Cl)c(C4(C)CS(=O)(=O)C5(CCOC5)C(=N)N4)s3)[nH]c12 +O=C(NC(=S)N1CCc2c(OCCCCCOc3ccc(Cl)cc3)cccc21)c1ccccc1 +Cc1cc(C(F)(F)F)cc(C2(Nc3ncc(C(=O)NO)cn3)CC2)c1 +Cc1cc(F)c(F)cc1-c1ccc(OCc2cccc3c(=O)n(CC(O)CO)[nH]c23)cc1 +CC#CCOC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +CC1(C)Oc2nc([N+](=O)[O-])cn2CC1OCc1ccc(OCc2ccccc2)cc1 +CCC(C)C=CC=CC=CC(=O)C=C(O)C1=C2C=C(CC(O)CO)C(=CNCc3ccccc3)C(=O)C2(C)OC1=O +COc1ccc2c(c1)C(=Cc1cc(C(=O)c3cc(OC)c(OC)c(OC)c3)ccc1OC)C(=O)N2 +CCOc1cc(CN2CC3(CC(N4CCC(F)(C(=O)O)CC4)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +CNCCN1CCC(OCc2cccc(C(F)(F)F)c2)CC1 +CN1C(=O)C(Cc2ccc3ccccc3c2)c2c(CCC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)cccc21 +COc1ccccc1-c1cn(-c2ccc(C(=O)O)c(O)c2)cc1C#N +CNC(C)C(=O)NC(C(=O)N1CSCC1C(=O)NCC(c1ccccc1)c1ccccc1)C1CCCCC1 +Cc1oc2c(c1C(=O)c1ccc(Cl)cc1)C(=O)C(=O)c1ccccc1-2 +COc1cc2[nH]c(C)c(-c3ccc4c(c3)OCCO4)c(=O)c2cc1Cl +COc1cc(-c2ccc3ncc(C#N)c(NC4CCC(N(C)C)CC4)c3c2)cc(Cl)c1O +Cn1nnc(C2CC3(c4ccccc4)NC2CCC3OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1 +COc1ccc(C)c(OC(CCN2CCC(n3c(=O)n(CC(=O)NC4CCC4)c4ccccc43)CC2)C(C)C)c1 +CCCCNC(=O)C(C)CC(O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CC(C)C)NC(C)=O +O=C(NC1CCN(C(c2ccc(C(F)(F)F)cc2)c2cnccn2)CC1)C1CC1 +CN1CCN(CC2CC3c4ccccc4Cc4ccccc4N3O2)CC1 +Nc1nc2ncc(CNc3ccc(C(=O)NC(CCC(=O)NCCCCCCCCC(=O)NO)C(=O)O)cc3)nc2c(=O)[nH]1 +O=C(Nc1cccc(Cl)c1)NC1CCN(CCOc2ccccc2-c2ccccc2)CC1 +CN1CCN(c2cc(OCc3cc(F)c(Oc4ccc(Cl)c(C(F)(F)F)c4)c(F)c3)nc(=O)n2C)CC1 +Cc1cc(-c2cc(O)ccc2Cl)cc2nnc(Nc3ccc(C(=O)NCCN4CCCC4)o3)nc12 +O=S(=O)(NC1CCN(CCOc2cccc(F)c2)C1)c1cccs1 +NC(CC(=O)N1CC(CO)C(c2ccc(Cl)c(NC(=O)Cc3ccc(F)cc3)c2)C1)Cc1ccc(Cl)cc1 +CCOc1ccc(-n2cc(CCc3ccccc3)c3cc(CCC(=O)O)ccc32)cc1 +Nc1cc2n[nH]c(=O)n2c2cc(-c3ccco3)ccc12 +Fc1cc(F)cc(-c2ccc3c(c2)C2(CCCCC2)C(S)=N3)c1 +O=Cc1cn2c3c1ccc1c4ccccc4n(c13)CC(O)C2 +CC(C)(NC(=O)c1nc(-c2cccc(-c3ccc(N)nc3)c2)cnc1N)C1CCNCC1 +COCCCN(Cc1ccccc1-c1ccc(CN2CCNCC2)cc1)S(=O)(=O)c1ccc(F)cc1 +CC1=CC(C)(C)N(Cc2ccncc2)c2ccc(O)cc21 +CCOc1cnc(Nc2ccc(CCC3COC(N)=N3)cc2)nc1 +CCNC(=O)Nc1cc(-c2cccnc2)c(-c2cncc(C(=O)O)c2)cn1 +CCCC(NC(=O)Cc1cc(F)cc(F)c1)C(=O)Nc1nc(C)c(C(C)NCC(C)C)s1 +O=C(CCCN1CCC(Cc2ccccc2)CC1)c1ccc(F)cc1 +CC1CCC(C(C)C)C(NC(=O)Oc2ccc(C(F)(F)F)cc2)C1 +CCN(CC)CCCN(Cc1cc2cc(OC)ccc2[nH]c1=O)C(=S)Nc1cccc(Cl)c1 +N#CCC1(COC(=O)N2CCC(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)C(C#N)C2)CC1 +Cc1cc(C#N)cc(C)c1Oc1ccc([N+](=O)[O-])c(NC2CCN(Cc3ccc(S(C)(=O)=O)cc3)CC2)c1 +CCC(NC(=O)N1CCc2cnc(NC(C)CO)nc2C1)c1ccc(OC)c(Cl)c1 +Cc1c(C#N)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1cccc(F)c1 +Nc1nc(O)c2ncn(CCCCCCC(F)(F)P(=O)(O)O)c2n1 +Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ccc(-c3ccccc3)cc1)c1ccc(C#N)cc12 +CCCCCCCNC(CNC(=O)Nc1c(C(C)C)cccc1C(C)C)c1ccccc1 +COc1ccc(C2=NN(c3nc(-c4ccc(Cl)cc4)cs3)C(c3ccc(O)c(OC)c3)C2)cc1 +COc1cc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)ccn1 +CC(CO)(CO)n1cc(C(=O)c2cncc(NC(=O)Cc3cccc(C(F)(F)F)c3)c2)c2cncnc21 +COc1ccc(F)c(N2CCC(Oc3ccc(N4CC(C(F)(F)F)CC4CC(=O)O)cc3)CC2)c1 +CNC(=O)c1oc(C(C)(C)C)cc1NC(=O)Nc1ccc(C)cc1 +CCN(NC(=O)c1cc(OC)no1)C(=O)NCc1ccc(-c2cc(Cl)cc(F)c2-c2noc(C)n2)cc1F +NC(Cc1nc2c(Cl)ccc(Cl)c2nc1CP(=O)(O)O)C(=O)O +Cc1ccn(NS(=O)(=O)c2ccc(Cl)c(Cl)c2)c(=O)c1CC(=O)NCc1ccc(C(=N)N)cc1 +CSc1ncc(C2C(C(=O)OC(C)(C)C)=C(C)NC(C)=C2C(=O)OC(C)(C)C)n1Nc1ccccc1 +CN(C)c1ncnc2c1nc(O)n2Cc1cccc(NC=O)c1 +CCCCN(c1cccc(-c2ccc(Cl)cc2)c1C)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(F)c1Cl +CCCCN(CC)c1nc(C)nc2c1nnn2-c1c(C)cc(C)nc1C +O=S(=O)(Nc1nccs1)c1ccc(Oc2ccccc2-c2ccccc2)c(F)c1 +NCCn1cc(S(=O)(=O)c2cccc3ccccc23)c2cccnc21 +COc1cc(C(=O)N2CC(OC)C2)ccc1Nc1ncc2ccnc(NCC(C)(C)C)c2n1 +Oc1cccc(CNc2ccc3c(c2)CC2C4CCCCC34CCN2CC2CC2)c1 +COc1cc(NC(=O)C=CC(=O)c2c(C)c(C)cc(C)c2C)cc(OC)c1 +CC(C)n1nc(-c2cccc3[nH]ccc23)c2c(N)ncnc21 +Cn1ncc2c(Cl)cc(-c3ccc(C4(C)CCCNC4=O)c(=O)[nH]3)cc21 +COC(=O)NC(C)CNc1nccc(-c2cn(C(C)C)nc2-c2cc(C)cc(NS(C)(=O)=O)c2F)n1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(c4ccccn4)CC3)c(C(F)(F)F)c21 +CCC(CC)OC(=O)c1cn(Cc2ccccc2F)c2cc(-c3ccc(N)cc3)c(CN(C)Cc3ccccc3)n2c1=O +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4cc(Cl)ccc4n3)cc2)no1 +CC(C)(C)c1cc(C(=O)N2CCS(=O)(=O)CC2)c(NC(=O)Nc2ccc3[nH]ncc3c2)s1 +Cc1ccc(S(=O)(=O)N(CC(C)C)C(CO)CCCCNC(=O)OC2c3ccccc3-c3ccccc32)cc1 +CC1CCCN1CCc1ccc2nc(-c3cc(Br)no3)ccc2c1 +N#Cc1ccc(Cn2cncc2CN(CCCN)C2CCN(Cc3ccccc3)C2=O)cc1 +CN(CCOCCNC(=S)NC(=O)c1ccc2c(c1)C(=O)c1ccccc1-2)Cc1ccccc1 +COc1cc2c3c(c1O)C(=O)c1ccccc1C3=NCC2 +O=C(NC1CCCC1)C1CN(c2cccc(C(F)(F)F)c2)CC(=O)N1c1cccc(OC(F)(F)F)c1 +O=C(NCCCNc1nc(Nc2ccc(N3CCOCC3)cc2)ncc1C1CC1)C1CCC1 +CNS(=O)(=O)c1ccc(OCC(F)(F)F)c(Nc2cc(Nc3ccc(Cl)cn3)ncn2)c1 +CC(N)c1cc(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)cc(C(F)(F)F)c1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(C)(C(F)F)Oc4ccccc43)cc21 +CCCOc1cc2oc(-c3ccccc3)cc(=O)c2c(OC)c1OCCC +CC(C)(C)c1ccc(-n2c(O)nnc2Sc2ncc([N+](=O)[O-])s2)cc1 +CCCNC(=O)c1ccc(NC(=O)N2Cc3ccc(C(N)=O)cc3C2)cc1 +NC(=O)C(Cc1ccccc1)NC(=O)C(CCS)NC(=O)c1cc(O)cc(C(=O)O)c1 +NS(=O)(=O)c1cnccc1N1CCN(c2ccc(Cl)c(Cl)c2)CC1 +Clc1cnc2nc(-c3ccc(CN4CC(c5nnc(-c6ccccn6)[nH]5)C4)cc3)c(-c3ccccc3)cn12 +COc1ccc(Nc2nnc(SCc3ccncc3)[nH]2)cc1OC +Cc1cnc(Cl)nc1-c1ccc2c(c1)CCC(c1cccnc1)N2C(=O)c1ccc(O)cc1O +CC(NCCc1cc(Cl)c(NCC(=O)O)cc1Cl)C(O)c1ccc(O)cc1 +O=C(NCC1CCC(CCOc2ccccc2)CC1)c1ccc(O)nn1 +Cc1ccc(CSCCNS(=O)(=O)c2ccc([N+](=O)[O-])cc2)cc1 +Cc1cccc(NC(=O)c2c(NO)cc(-c3cccs3)oc2=O)c1 +O=C(C=Cc1c(C(=O)O)[nH]c2cccc(Cl)c12)Nc1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 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+CCOC(=O)c1ccc(NC(=O)CSc2nnc(CNc3ccccc3)n2CC)cc1 +Cc1ccc(C(=O)Nc2cc(N(C)CCN(C)C)cc(C(F)(F)F)c2)cc1Nc1ncnc2cnc(N(C)C)nc12 +O=C(COc1cccc(F)c1)NCC(O)CN1CCc2ccccc2C1 +Cc1c(Cl)cc2c(c1C)OC(C(F)(F)F)C(C(=O)O)=C2 +O=C(Cc1cccc2ccccc12)Nc1ccc2c(c1)ncn2Cc1ccccc1 +CCc1cc(=O)oc2cc(OCCCCN3CCC(c4noc5cc(F)ccc45)CC3)ccc12 +O=C1C(c2ccccc2)=COC12CCN(Cc1ccccc1)C2 +CC(NC(=O)C1(NC(=O)C(F)(F)F)CC1)c1ncc(-c2cc(Cl)cc(Cl)c2OCC(F)F)cc1F +CCOc1ccccc1-c1ccc(-c2nc3ccncc3c(O)c2C#N)cc1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2)CC1)C1CCC(=O)N1C(=O)C1CCCCC1 +CC(C)ON(OC1OCC(O)C(O)C1O)C1CCC2(C)C(CCC3C2CCC2(C)C(C4=CC(=O)OC4)CCC32O)C1 +CS(=O)(=O)CC(N)c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)o1 +CC1CC(N(C(=O)CCCC(=O)O)c2ccccc2)c2ccccc2N1C(=O)c1ccccc1 +Cc1cc(OC2CC2)ccc1N1CCC(Oc2ccc(C(C)NC(=O)c3cn[nH]c3)cc2)C1 +Cn1cc(C2=C(c3c4n(c5ccccc35)CCC(N)CC4)C(=O)NC2=O)c2ccccc21 +CCOc1cc(CN2CC3(CC(CCC(=O)O)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +CC(C)n1nc(C(=O)NC2CC3CCC(C2)N3CC(O)CN2CCC(CNS(C)(=O)=O)CC2)c2ccccc21 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+CCCCCCCN(CCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1)C(=O)Cc1ccc(F)cc1F +COc1ccc(-c2cc3ccc(N(C)C)cc3c(N)n2)cc1OC +c1ccc(CCNc2nc(-c3ccc4[nH]ncc4c3)cs2)cc1 +CCN(CC)c1nc(NCCNC(=O)c2cc(O)c(O)c(OC)c2)c2ccccc2n1 +OCCNc1cc(N2CCc3ccccc3C2)c2ccccc2n1 +O=C(NCC1CCOCC1)c1cnc(Nc2cccc(F)c2F)nc1C(F)(F)F +COc1ccc(CCNC(C)COc2c(C)cccc2C)cc1OC +CC(=O)Nc1ccccc1-c1ccc2[nH]c(C=Cc3ccc(C(C)(C)C)cc3)nc2c1 +N#Cc1cccnc1N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +N=C(N)Nc1cccc(C(=O)NNC(=O)NC(CC(=O)O)c2ccc(Cl)cc2)c1 +CCC12CCC(=O)C(Cl)=C1c1ccc3[nH]nc(F)c3c1C2 +O=c1ccc(Cc2cc(Cc3cccc(Cl)c3)c3occc3c2)n[nH]1 +COC(=O)Nc1noc2cc(-c3c(C)n[nH]c3C)ccc12 +COc1ccc(C2(c3cc(OC)c(OC)c(OC)c3)CC(c3ccc(Cl)cc3)=NO2)cc1O +Clc1ccc2c(NCCN(CCN(Cc3ccccc3)Cc3ccccc3)CCN(Cc3ccccc3)Cc3ccccc3)ccnc2c1 +Cc1ccc(CC(=O)c2sccc2S(=O)(=O)Nc2onc(C)c2Br)cc1 +Cc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1-c1ccc2nc(N)ncc2c1 +CCCCn1c(CNc2cccc(C(=O)O)c2)nc2cc(OC)c(OC)cc2c1=O +CC(C)Oc1ccc(N=c2[nH]c(=O)n(CC3(C(=O)O)CC3)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +CCc1c(-c2cnc3ccc(N(CCNCC(F)(F)F)c4cc(OC)cc(OC)c4)cc3n2)cnn1C +COc1ccc([N+](=O)[O-])cc1CSc1nc2cc(NC(=O)NC(C)(C)C)ccc2n1Cc1cccnc1 +C=C(c1ccc(OC)cc1)c1cc(C#N)nc2ccccc12 +COc1cc(NC(=O)c2ccc(Cc3ccccc3)cc2)ccc1OCCN(C(C)C)C(C)C +CC(=O)c1cccc(Nc2nc(-c3ccccc3)cs2)c1 +CCCCN(CC)c1nc(C)nc2c1NCCN2c1ccc(OC)cc1C +Oc1cccc(-c2cccnc2Oc2ccc(Nc3ccccn3)cc2)c1 +CC(C)(C)NC(=O)c1ccc(OCC(=CF)CN)cc1 +Cc1nc(NCc2ccc(F)cc2)nc(-n2ccnc2C)c1[N+](=O)[O-] +O=[N+]([O-])c1c(Nc2cccc(Cl)c2)ccc2nonc12 +Cc1nccc(-c2ccc(F)c(C(=O)N(C)C3CCN(C)C3)c2)c1C#Cc1ccc(N)nc1 +[C-]#[N+]CC(=O)N1CCC(CCNC(=O)c2cnc(-n3ncc4cc(C#N)cnc43)cc2NC(C)C)CC1 +FCCOc1ccc(CN2CCN(Cc3cc4ccccc4o3)CC2)cc1 +COC(=O)N1CC(C(=O)Nc2ccc(Cl)cc2)C(C(=O)Nc2ccc(-n3ccccc3=O)cc2F)C1 +COC(=O)c1c(NC(=O)C23CC4CC(CC(O)(C4)C2)C3)sc2c1CCCC2 +CS(=O)(=O)c1ccc2c(=O)n(C(CC3CCCCC3)C(=O)Nc3ncc(Cl)s3)c(=O)[nH]c2c1 +Cc1ccc(S(=O)(=O)N2CCN(c3nc(SCc4nc5ccccc5[nH]4)nc(-c4ccccc4)c3C#N)CC2)cc1 +CCC1(O)c2cc3n(c(=O)c2COC(=O)C1OC(C)=O)Cc1cc2cc(OC)ccc2nc1-3 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+O=C(NCC(c1cnc(C(F)(F)F)nc1)C1CCC(F)(F)CC1)c1cccc(Cl)c1Cl +N#Cc1cnc(C(=O)Nc2ccc(C=CC(=O)O)cc2C2=CCCCC2)[nH]1 +CC(C)N1CCC(N(C)C(=O)N2CCC(n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)C2)C1 +COc1cc(Cc2cnc(N)nc2N)cc(OCCCC(=O)O)c1OC +NC1(C(=O)O)C(OCc2cccc(F)c2F)CC2C1C2(F)C(=O)O +Cc1ccc(-c2nn(CCCCO)cc2C(=O)Nc2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)cc1 +O=[N+]([O-])c1cn2c(n1)OCC(Oc1ccc(-c3ccc(F)cc3)cn1)C2 +O=C(NCC(c1ccco1)N1CCCC1)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +N#Cc1cnc2c(NC3CC3)nc(Nc3cc(C(F)F)cc(N4CCN(C5(C#N)COC5)CC4)c3Cl)nn12 +CCCCCCCC1CC(C(=O)Nc2c(C(C)C)cccc2C(C)C)C(=O)O1 +CC1CC(c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)CC(N)C1=NO +Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-c3ccc(N(C)C)nc3)c1)=N2 +CC(C)CN(CCCN1CCN(CCCNC(=O)c2ccc3ccccc3c2)CC1)CC(C)C +COc1ccc(N2CCN(c3ccc(C)c(C(F)(F)F)c3)C2=O)cc1OCCN1CCCCC1 +Cc1nc(-c2ccccc2C(=O)N2CC(Oc3cc(C#N)ccn3)CCC2C)no1 +O=C(CCc1nc(-c2ccc(F)cc2Cl)no1)Nc1cnc2ccccc2c1 +CCCCCNC(=O)Nc1c(C)cccc1OCCCn1cnc(-c2cc(OC)c(OC)c(OC)c2)c1 +CN(C)NC(=O)Nc1cccc2c1C(=O)c1c(-c3cccs3)n[nH]c1-2 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+O=S(=O)(NCCOC12CCCCC1(S(=O)(=O)c1ccc(Cl)cc1)c1c(F)ccc(F)c1OC2)C(F)(F)F +O=C(NCC1CN(c2ccc(N3CCSCC3)c(F)c2)C(=O)O1)c1cccs1 +CC(NC(=O)c1cn[nH]c1)c1ccc(CN2CCc3c(cccc3C(F)(F)F)C2)cc1 +COC(=O)c1cc(N)c(Nc2ccc(C#N)cc2)cc1Oc1c(Br)cc(CCC#N)cc1OC +Cc1c(NC(=O)NC2CCCCC2)cccc1-c1nc(Nc2ccc(C(=O)N3CCOCC3)cc2)c2nc[nH]c2n1 +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1ccccc1Br +O=S(=O)(c1c(Cl)nc2sccn12)n1ccc2ncc(-c3cnn(C4CCNCC4)c3)cc21 +O=C1CCC2(O)C3Cc4ccc(O)cc4C2(CCN3CC2CC2)C1 +COc1cc(-c2ccc3ncc(C(=O)C(C)C)c(NC4CCC(N)CC4)c3c2)cc(Cl)c1O +CN(C)CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +CNC1CC(c2ccc(Cl)c(Cl)c2)c2ccc(F)cc21 +CN(C)c1ccccc1C(=O)OCC1(CO)CC(=Cc2ccc([N+](=O)[O-])cc2)C(=O)O1 +O=C(Nc1ccc(-c2csc3c(=O)cc(N4CCOCC4)oc23)cc1)c1cccnc1 +COc1cc(Cl)ccc1OC(c1cccc(F)c1)C1CNCCO1 +O=C(Cc1ccccc1)NCc1cc(Br)cc2nc(O)c(O)nc12 +CC1(c2cc(NC(=O)c3cnc(-c4ccco4)cn3)ccc2F)CCSC(N)=N1 +Cc1ccsc1-c1ccc(CCC(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(N)=O)cc1 +c1nc(NC2CCCCC2)c2cc(-c3cncs3)ccc2n1 +COCCOc1n[nH]c2cc(NC(=O)NC(COC)c3ccc(F)cc3)ncc12 +CCN=C(NCc1ccc(Cl)cc1)SCCCc1c[nH]cn1 +CC(C)(C)OC(=O)NC(Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1C(C)(C)C +CCCCCCCCCCC#CC(O)c1ccccc1-c1ccc(Oc2ccc(OCC)cc2)c(S(=O)(=O)O)c1 +COc1cc2c(Nc3ccc(-c4nc5ccccc5s4)cc3OC(F)(F)F)ncnc2cc1OCCCN1CCN(C)CC1 +CCCCc1nn(CC(=O)c2ccccc2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1cccn2c(C)c(N(Cc3ccc(F)c(C(F)(F)F)c3)S(=O)(=O)c3ccccc3)nc12 +CSc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1ccccc1C(F)(F)F +COc1ccc(N2CCc3c(-n4ccc(-n5cc[nH]c5=O)n4)cc(C)nc32)c(C)c1 +OC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +CCOc1ccc2c(c1)CCN(Cc1ccc(C(C)NC(=O)C3CC3)cc1)C2 +O=C(NCCN1CCCC1)c1cc(Nc2cc(C3CC3)[nH]n2)nc(NCc2cc(-c3ccccc3)no2)n1 +O=c1c2cc(OCCCN3CCCCCC3)ccc2nc2n1CCCc1ccccc1-2 +COc1ccccc1N1CCN(CCCCc2cn(-c3ccc4[nH]ccc4c3)nn2)CC1 +CN(C)CC1CCC(c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)CC1 +Cc1ccc(-c2c(CN)c(CC(C)C)nc3ccc(CCC(N)=O)cc23)cc1 +Fc1ccc(C(NCC2CCN(CCc3ccccc3)CC2)c2ccc(F)cc2)cc1 +CCCCCC(O)C=CC1CCC(=O)N1CCSc1nc(C(=O)O)cs1 +NCCCc1cc2cc[nH]c(=O)c2c2cc(-c3ccc(CN)cc3)ccc12 +CCCOc1c(NC(=O)N(O)C(C)CC)cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc1OC +CC1CC2OC2C=CC=CC(=O)Cc2cc(O)cc(O)c2C(=O)O1 +CN1CCC(Nc2cc(S(=O)(=O)n3ccc4ccccc43)ccc2F)CC1 +O=C(Nc1cccc(Cl)c1)ON=C1CCCCC1Cc1cccs1 +N=C(N)Nc1nc(C(CCN2CCC(c3ccccc3)CC2)C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)cs1 +CN(C)CC=CC(=O)N1Cc2sc3ncnc(Nc4ccc(F)c(Cl)c4)c3c2C1 +O=C(NCc1ccc(S(=O)(=O)c2ccccc2)cc1)c1nc2ccncc2s1 +Brc1ccc(-c2nnc3sc(CN4CCN(c5ccccc5)CC4)cn23)cc1 +O=C(NC1CCCC1Nc1cnc(C(F)(F)F)cn1)c1ccccc1-n1ccnn1 +CC(O)C(N)C(=O)NS(=O)(=O)c1cccc(-c2ccc3c(N)ncnc3c2)c1 +CN1C(=O)C(C)(C)C(C)(c2cc(Nc3cccc(C#N)c3)ccc2F)N=C1N +CCC(Nc1nc2c(c(=O)n1OC)CN(C(=O)c1ccc(C#N)cc1F)CC2)c1ccc(C(F)(F)F)cc1 +COc1ccc2[nH]c(C(=O)c3cc4ccc(Cl)cc4[nH]3)cc2c1 +CCC(c1cc(C)no1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COc1ccc(-c2cc3c(C)nc(N)cc3n(C3CCCC3)c2=O)cn1 +COc1ccc2cc(C(=O)Nc3ncc(Cc4cccc(C(F)(F)F)c4)s3)ccc2c1 +O=C(NCc1ccc(Br)cc1)OCc1cn(-c2cc3nc(C(=O)O)c(O)nc3cc2[N+](=O)[O-])cn1 +Cn1cccc1C(=O)NCc1cc(Br)cc2nc(O)c(O)nc12 +CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC1(CC2)CC1 +Clc1ccc(-c2ccc(-c3nccn3-c3ccc(N4CCNCC4)cc3)o2)cc1 +CCCC(=O)c1cnn(-c2ccc(NC(=O)c3cn(CC(=O)N4CCN(C)CC4)c4cc(Cl)c(C)cc34)cc2)c1C +CS(=O)(=O)c1ccc(NC(=O)c2cc(N(CC3CC3)C3CCCCC3)ncn2)cc1 +O=C(CCCCC#Cc1ccccn1)c1ncc(-c2ccccn2)o1 +CC(Sc1nc(-c2ccc(Cl)c(F)c2)c(C#N)c(=O)[nH]1)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CC1=CC(=O)N(Cc2ccc(C#N)cc2)S(=O)(=O)O1 +O=C1c2cccc3cccc(c23)C(=O)N1CCCNCCCCCCCCNCCCN1C(=O)c2cccc3cccc(c23)C1=O +COCC12CNCCC1(c1ccc(C(F)(F)F)c(Cl)c1)C2 +Fc1ccn(Cc2cccc3c2CCC3c2ncc[nH]2)n1 +Cc1ccc(S(=O)(=O)c2cc3cnc(Nc4ccc5[nH]ccc5c4)nc3n(C)c2=O)cc1 +CCC(NC(=O)C(NC(=O)C(CCCc1ccccc1)CC(=O)O)C(C)(C)C)c1ccccc1 +COc1cc(CCc2nc3c(OC)ccc(C)n3n2)nc2ccccc12 +CCN(CCO)Cc1csc(-c2cn(CC3CCOCC3)c3c(Cl)cccc23)n1 +[H]C([H])([H])NCCC(Oc1ccccc1OC)c1ccccc1 +CCc1nnc2n1C1CCN(C(=O)CC(N)Cc3cc(F)c(F)cc3F)CC1CC2 +O=C(CC1(C2COC3CCCC3N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC(O)C1 +c1cc2oc(N3CCN4CCC3CC4)nc2nc1C1CCCC1 +CCN(CC)CCNC(=O)Cc1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +CCS(=O)(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CCC3CC4)cc2)cc1 +COCCN(CC1CCCN(C2Cc3ccccc3C2)C1)C(=O)c1ccc2ccccc2c1 +Cc1c(-c2nnc(C(C)(C)C)o2)nc(-c2ccccc2Cl)n1-c1ccc(Cl)cc1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)c1nnn(-c2ccccc2)c1C(F)(F)F +CCCOC(=O)Oc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +Cc1cc(S(=O)(=O)Nc2ccc3c(c2)CCN(C)CC3)ccc1-c1ccc(Cl)cc1 +O=C(c1ccc(F)c(Cl)c1)N1CCC(F)(CNCc2ccc(CO)cn2)CC1 +Cc1ccc(C(CCNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(F)cc2)cc1 +CN(C)Cc1ccc(-c2ccc3ccn(C(N)=O)c3n2)cc1 +Cc1cccc(C)c1C(=O)NCc1ccc(-c2cc[nH]c(=O)c2)cc1 +Cn1cc(-c2ccncc2)c(-c2ccc(OCc3nc4ccccn4n3)cc2)n1 +COc1cc(O)cc(C=Cc2cc(C(C)(C)C)c(O)c(C(C)(C)C)c2)c1 +CN(C)CCn1cc2c3c(cccc31)C1=CC(C(=O)N3CCCC3)CN(C(=O)Nc3ccccc3)C1C2 +N=C(N)c1ccc(OC(=O)c2ccc(CC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)O)o2)cc1 +N#Cc1cc(F)cc(-c2ccc3nc(O)n(-c4ccccc4)c3c2)c1 +CCN(CC)C1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nc2)CC1 +COC(=O)CN1CC(Nc2nc3cc(C)ccc3[nH]2)C(OC(=O)c2ccc(-c3ccccc3)cc2)C1 +CCCC1OC(O)=C2C1=NC1=C(C(=O)COC1)C2c1ccc(Br)c(Cl)c1 +Cc1cnc(-c2cccc(Cn3nc(-c4cc(F)cc(F)c4)ccc3=O)c2)nc1 +Cn1cnc(-c2ccnc(Nc3cc(Cl)c4[nH]c(C(=O)NCC5CCOCC5)cc4c3)n2)c1 +C1=CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +CCCCc1nc(C(F)(F)c2ccc(-c3ccccc3-c3nn[nH]n3)cc2)n(CCCC)n1 +CN(C(=S)Cc1cccc2sccc12)C1CCCCC1N1CCCC1 +COc1cccc(Nc2nc3cc(C(=O)O)ccc3c3scnc23)c1 +COc1ccccc1-c1c[nH]c2ncnc(N3CCC(F)C3)c12 +CNC(=O)C1Cc2ccccc2N1C(=O)COc1ccccc1 +CCc1cccc(NC(=O)N2CCc3nc(-c4cccnc4)nc(-c4c(Cl)cccc4Cl)c3C2)c1 +CC(C)N(C(=O)OC1CN2CCC1CC2)c1ccccc1 +O=C(Cc1ccc(OCc2ccccc2)cc1)N(O)CCc1ccccc1 +O=C1NC(=O)c2c1c1c3ccc(C(F)(F)F)c(CO)c3[nH]c1c1c2c2cccc3c2n1CCNC3 +COc1cccc2nc(C)c3nnc(-c4ccccc4Cl)n3c12 +CCCc1c(OCCCOc2cc(O)c(-c3ccc(F)cc3)cc2CC)cccc1Oc1ccccc1CC(=O)O +CCOC(=O)c1c(C)nc(Nc2ccc3nc(C)sc3c2)n(Cc2ccc(Cl)cc2)c1=O +NC(=O)n1cc(NC(=O)N2C(C(=O)NCc3cccc(Cl)c3F)CC3CC32)c2cc(OCCN3CCCC3)ccc21 +Cn1c(=O)c2c(nc(N3CCCC(N)C3)n2Cc2ccccc2Cl)c2cc(CC(=O)O)ccc21 +CC1CCC(=O)N1c1ccc2cc(NC(=O)C3CC3F)ncc2c1 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2cc(C#N)cn2)n1 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+C=CCN(C(=O)c1ccc2c(c1)nc(NC(=O)c1ccccc1)n2CCC(N)=O)C1CCCCC1 +COc1cc(-c2cnc(N)c3c(-c4cccc(Cl)c4Cl)csc23)cc(OC)c1OC +Cc1c(-c2ccnc(N)n2)sc2ccc(C(N)C(C)C)cc12 +O=C(c1ccccc1)C1CCN(C2Cc3ccccc3CC2O)CC1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ncc(-n5cnnn5)cc4OC)CC3CO2)c1C +CCCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1nc(C)c(Br)c(=O)[nH]1 +NC(=O)n1cc(NC(=O)N2C(C(=O)NCc3ccccc3F)CC3CC32)c2cc(OCC(=O)O)ccc21 +Cn1c([N+](=O)[O-])cnc1C=Cc1ccc(Cl)cc1 +O=C(C1CCCCC1)N1CC(=O)N2CCc3ccccc3C2C1 +COc1c(Cl)cc(Cl)c(O)c1C(=O)NCC1CCCN1Cc1ccc(F)cc1 +Cc1cc(C)nc(OC(C(=O)O)C2(c3ccccc3)NCCOc3ccccc32)n1 +CCCN(CCCCNc1ccnc2cc(Cl)ccc12)Cc1ccc(C)o1 +Cn1ncc(-c2ccncc2)c1-c1ccc(OCc2cc(OCCOCCF)c3ccccc3n2)cc1 +Fc1cc2nc(SCC3CCCCC3)[nH]c2cc1N1CCNCC1 +CCC(CS(=O)(=O)c1ccccc1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COC1CCN(c2nc(NC3CCCNC3)c(-c3ccc4ccccc4n3)c(=O)[nH]2)C1 +CC[n+]1c(C=C2Sc3oc4ccccc4c3N2C)ccc2cc(C)ccc21 +CC(=O)N1CCN(C(=O)c2cc(Cc3c[nH]c(=O)c4cc(Cl)c(Cl)n34)ccc2F)CC1 +O=C(NCCO)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 +CCOC(=O)c1nnn(-c2ccc([N+](=O)[O-])cc2)c1C(O)C(O)C(C)O +CC(NC(=O)C1=C(O)C(=O)N(C)C1)c1cccc(-c2cccc(F)c2)c1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)C(CO)c3ccc(Cl)cc3)c2)c2cncnc21 +O=C(CN1CC(O)C(NC(=O)c2ccc(Cl)s2)C1)Nc1ccc(-n2ccccc2=O)cc1F +Cn1cc(-c2cc(Cl)cc3c2-c2ccccc2C3(O)C(F)(F)F)cn1 +O=C(CC1CCCCN1S(=O)(=O)c1cccc(C(F)(F)F)c1)NC1CCCc2cc(CNC3CC3)ccc21 +COC(=O)Nc1cc2c(c(N)n1)N=C(c1ccccc1)C(C)N2 +Cc1cc(C)cc(Nc2nccc(-n3cc(CN4CCC(O)CC4)c(C)n3)n2)c1 +CC12CCC3c4ccc(OS(N)(=O)=O)cc4CCC3C1CC(=O)N(CCC(F)(F)F)C2=O +N#CCOc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +Oc1ccc2c3c1OC1Cc4c([nH]c5ccccc45)C4C(C2)N(CC2CC2)CCC314 +Cc1nn(Cc2ccc(-c3nc4cc(Br)ccc4[nH]3)cc2)c(C)c1CC(=O)O +O=C(CN1C(=O)N(CC(=O)N2CCCC2)c2ccccc2N(c2ccccc2)C1=O)Nc1cccc(C(=O)O)c1 +CC1=CCC2C(C1)c1c(O)cc(C(C)(C)CCCCC(=O)Nc3ccc(S(N)(=O)=O)cc3)cc1OC2(C)C +CC(=CC(C(C)C)N(C)C(=O)C(NC(=O)C(N)C(C)(C)c1ccccc1C)C(C)(C)C)C(=O)O +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ncccn2)CC1c1ccc(F)cc1F +CNC(=O)c1cnn(-c2nc(N)c3ncn(C4OC(CO)C(O)C4O)c3n2)c1 +O=C(CC1CCCO1)NC1CCC(CCN2CCC(c3cccc4c3OCO4)CC2)CC1 +Cc1ccc(C(=NNC(N)=S)c2cccc(C(F)(F)F)c2)cc1 +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Br)o1)Oc1ccccc1-3 +COc1ccc(CC(Sc2ccc(OCC(=O)O)c(C)c2)c2sc(-c3ccc(C(F)(F)F)cc3)nc2C)cc1 +O=C(O)CCCC(=O)N1N=C(c2c(-c3ccc(Cl)cc3)c3ccccc3[nH]c2=O)CC1c1ccc(Cl)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4ccc[n+]([O-])c4)ncc23)ccn1 +Cc1ocnc1C(=O)Nc1ccc(N2C(=O)c3cccc(Cl)c3C2=O)c(Cl)c1 +COc1cc(-c2cccc(Cl)c2F)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CCC(CC)(NC(=O)c1cnc(N2CC(F)(F)C2)c(OCC2CC2)n1)C(=O)NC +CC(C)c1cc(Nc2nc(Nc3ccc(N4CCOCC4)cc3)ncc2Br)[nH]n1 +CC(C)n1nc(Cn2nc3ccccc3c2OCCCCO)c2ccccc21 +CCCC#Cc1ccc(-c2c(CC)c(C(=O)NN3CCCCC3)nn2-c2ccc(Cl)cc2Cl)s1 +O=C1C(c2ccc3ccccc3c2)C(c2ccc(O)cc2)N1c1ccc(O)cc1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)C(C)(C)C(=O)CC2 +CC(C)Oc1ccc(S(=O)(=O)N2CCN(c3ccc(Br)c(OCC(=O)O)n3)CC2)cc1 +O=C(OC1CCCN(Cc2ccccc2)C1)C(O)(c1ccccc1)c1ccccc1 +Cc1c(Nc2c(C#N)cncc2C=CCCCN2CCCCC2)ccc2[nH]ccc12 +CN1CCc2c([nH]c3ccccc23)CC(c2ccccc2)CC1 +O=C(C1CCOCC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +COc1cc(-c2ccc3oc(N4Cc5ccccc5C4)nc3c2)ccn1 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1ccc(F)cc1 +O=C(c1nn(C2CCCN(CCN3CCCC3)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CCn1cc(C(=O)C2CC2)c2cc(Nc3ncc(F)c(-n4cc(CN5CC(O)CO5)c(C)n4)n3)ccc21 +Cc1nc(CN2CCC(COCc3cc(C(F)(F)F)cc(C(F)(F)F)c3)(c3ccccc3)CC2)cs1 +CCc1ccc(C(=O)N(CCN2CCN(c3ccccc3OC)CC2)c2ccccn2)cc1 +CCOC(=O)N1CC2CCC(C1)C2NCCNC(=O)c1cccc(Cl)c1 +CCCCn1cc2c(nc(NC(=O)Nc3cccc(OC)c3)n3nc(-c4ccco4)nc23)n1 +CCCCCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(SC3CCCCC3)nc(-c3ccccc3)n2)CC1 +CN1CCc2nc(C(=O)NC3CC(C(=O)N(C)C)CCC3NC(=O)c3[nH]c4ccc(Cl)cc4c3Br)sc2C1 +CC1(C)N2Cc3ccccc3CC2C(=O)N1C(Cc1ccc(O)cc1)C(=O)O +CN1C2CCC1CC(OC(c1ccccc1)c1ccc(C(F)(F)F)cc1)C2 +CCOc1ccccc1C=CS(=O)(=O)Nc1ccccc1S(N)(=O)=O +CCOC(=O)N1CCN(CCOc2ccc(-n3ccnc3)cc2)CC1 +CC[n+]1c(C=Cc2ccc(N(C)C)cc2)sc2cc(NC(C)=O)ccc21 +O=C(Nc1ccc(C(=O)O)c(F)c1)c1ccc2c(c1)N(S(=O)(=O)c1cccc(C(F)(F)F)c1)CC2 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+Cc1nc(-c2c(F)cccc2-c2ccc(C(C)Nc3nccc(Cl)c3NC(=O)CC#N)cc2)no1 +CNc1nccc2c(OC(C)C(=O)N3CCN(C(=O)c4ccccc4)CC3C)cccc12 +COc1ncnc(NCc2ccc(S(N)(=O)=O)cc2)c1[N+](=O)[O-] +Oc1nc2ncc(-c3cnc(N4CCOCC4)c4nc(C=Cc5ccc6ccccc6n5)cn34)cc2[nH]1 +COc1ccc(C(=O)N2CCN(c3ccncn3)CC2)cc1C#Cc1cccc(Cl)c1 +O=C1NC(=O)c2c1c(-c1ccccc1)cc1c2c2cc(O)ccc2n1CCCNc1ccccc1 +COc1cc(OCc2cccc(OCc3ccccc3OC(F)(F)F)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CNC(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1 +N#Cc1c(NCCCNCc2cc(Br)cc(Br)c2)[nH]c2ccccc12 +O=C(Cc1ccc(O)c(Br)c1)NN=C1C(=O)Nc2ccccc21 +CC(=O)N1CC(N2CCC(c3cc(C#N)cc(Nc4nc(NC5CC5)c5ncc(C#N)n5n4)c3Cl)CC2)C1 +CC(C)CC(NC(=O)COc1cccc(N(C)C)c1)C(=O)NC(CC1CCNC1=O)C(=O)c1nc2ccccc2s1 +CCOC(=O)C1=C(CN2CCOCC2)NC(n2cncn2)=NC1c1ccc(F)cc1Br +CC1CC2C3CCC4N(C)C(=O)C=CC4(C)C3CCC2(C)C1O +O=C(NCCCCCCCn1cc(-c2cccnc2)nn1)Nc1ccccc1-c1ccccc1 +c1ccc(CNC2C3CC4CCC(C3)N4C2C(c2ccccc2)c2ccccc2)cc1 +CCCCn1cc2c(nc(N)n3nc(-c4ccco4)nc23)n1 +Fc1ccc(C(c2ccc(F)cc2)C2CCN(CCOc3cccc4ccccc34)CC2)cc1 +COc1cccc2c1c(C(=O)C=C(O)C(=O)O)cn2Cc1cccc(Cl)c1F +COc1ccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)cn1 +CN1CCc2cc(Cl)c(O)cc2C(c2ccc(CN(C)S(C)(=O)=O)cc2)C1 +COC(=O)Nc1ccc2c(c1)NC(=O)C(C)CCCC(N1CCC(c3cc(C)ccc3F)=CC1=O)c1cc-2ccn1 +CCCCNC(=O)NCCc1ccc2[nH]c3c(c2c1)CC1(O)C2Cc4ccc(O)c5c4C1(CCN2CC1CC1)C3O5 +O=c1cc(Nc2cccc(C(F)(F)F)c2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 +CC(Oc1cc(C(=O)NC(c2nnn(C)n2)C(C)(C)C)ncc1C1CC1)C(F)(F)F +Cc1c(N=C(N)c2ccccn2)ccc(-c2ccc(-c3ccc(N=C(N)c4ccccn4)c(C)c3C)o2)c1C +CNC1CCN(c2nc(N)nc3c2CCCC32CCCC2)C1 +CC(=O)N1CCn2cc(C3=C(c4cccc5c4OCO5)C(=O)NC3=O)c3cccc(c32)C1 +Nc1nc(N)c2c(OCC3CCN(CC(F)(F)F)CC3)cccc2n1 +COC(=O)C(C)(C)NC(=O)c1ccc(NC(=O)C(=O)c2ccccc2NC(C)=O)cc1 +CCCCC(CN(O)C=O)C(=O)NC(Cc1ccc(Cl)cc1)C(=O)N(C)C +COc1ccc2cc(C(C)Nc3nccc(N4C(=O)OCC4(C)C)n3)ccc2c1 +O=C(NC1CCCCC1)N1CCN(C(c2ccc(Oc3ccccc3)cc2)c2ccc(Cl)cc2Cl)CC1 +CC(C)(C)OC(=O)c1ncn2c1CN(C(=O)N1CCNCC1)c1ccccc1-2 +COc1cc2ncnc(Nc3ccc(B(O)O)cc3)c2cc1OC +O=C(NCCN1CC2CC(n3c(=O)[nH]c4ccccc43)CC2C1)c1ccc(Br)cc1 +O=C(C=Cc1ccccc1)OC1C2OC(=O)CC2OC1C(O)c1ccccc1 +O=S(=O)(NC1CCNC1)c1ccc2[nH]c(-c3cc4ccccc4nc3O)cc2c1 +COc1c(C(=O)C=Cc2cc(Br)cs2)c(O)c(OC)c2occc12 +Cc1ccc(C(=O)NC(C)C(N)=O)cc1-n1cnc(OCc2ccc(F)cc2F)c(Cl)c1=O +CCCc1cc(F)c(N)c2nc(-c3ccc(P(=O)(O)O)o3)n(CC(C)C)c12 +Cc1c(COC(=O)NC(C)C)c(COC(=O)NC(C)C)c2n1Cc1c(c3ccccc3n1Cc1ccccc1)C2 +CC(=O)c1cc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3)C2)cc(-c2nnnn2C)c1 +Cc1cccc(C(=O)NC2CC(n3cnc4c(NCC5CCCCC5)ncnc43)C2)n1 +Cc1ccccc1C(=O)c1csc(NCCCNS(=O)(=O)c2cccc(F)c2)n1 +Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC(O)c3c(C)cccc32)cc1 +Oc1ccc(Br)c(C(Nc2ccccn2)c2ccc3cccnc3c2O)c1 +CCOc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2cccc(C(F)(F)F)c2)CC1 +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)COc1ccc2[nH]c(=O)c(S(C)(=O)=O)c(CCc3ccccc3)c2c1 +CC(C)(C)OC(=O)N1CCC(C2CCN(c3ccc(S(C)(=O)=O)cc3)CC2)CC1 +c1ccc2oc(-c3ccc(OCCCCNc4c5c(nc6ccccc46)CCCC5)cc3)nc2c1 +CC1CN(C)C2(CCCC2)CN1C(=O)N1Cc2c(NC(=O)c3ccccn3)n[nH]c2C1(C)C +COc1ccc2c(OCc3nnc4ccc(-c5cc(F)c(F)c(F)c5)nn34)ccnc2c1 +Cc1c(NS(C)(=O)=O)cccc1N(Cc1ccc(Oc2ccc(Br)c(OCC(=O)O)c2)cc1)Cc1ccc(F)cc1F +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)C4CCc5cc(-n6cnnn6)ncc54)CC3CO2)c1Cl +O=C(c1ccc(Cl)cc1)c1ccc(OC2CN3CCC2CC3)cc1 +Cc1cccc2nc(-c3c(NC4CCCNC4)nc(N4CCOCC4)[nH]c3=O)sc12 +CC(=O)N1c2ccc(-c3ccc(C(=O)O)cc3)cc2C(Nc2ccc(C)cc2)CC1C +C[N+](C)([O-])CCNc1ccc2ncn3c4ccc(F)cc4c(=O)c1c23 +CC(C)(C)c1ccc(-c2ccc(Cl)cc2)cc1NC(=O)C1CCC2C3CNC4=CC(=O)CCC4(C)C3CCC12C +COc1cccc(NC(=O)c2ccc(C)c(Nc3nc4ccccc4n3-c3cc(N)ncn3)c2)c1 +CCC(=C(c1ccccc1)c1ccc(C=CC(=O)N2CCOCC2)cc1)c1ccccc1 +Cc1c(NS(=O)(=O)c2ccc(-c3ccccc3CN(C)C)cc2)c(CC(C)C)nn1C +Cc1cc(NC(=O)c2ccc(C#N)cn2)cc(C2(C(F)F)N=C(N)OC3CC32)c1F +CN(C)CCOc1ccc(C(=C(CCCN=[N+]=[N-])c2ccccc2)c2ccc(O)cc2)cc1 +CN1CCN(C(=O)c2cc3cc(Nc4nccc(-c5cc(OC6CCOc7ccccc76)ccn5)n4)ccc3[nH]2)CC1 +CCCCCn1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)c2cc(-c3cccs3)ccc21 +COc1cccc(C(=O)NC2(C(=O)NC(Cc3ccccc3)C(=O)NCC3CCN(CC4CCOCC4)CC3)CCCC2)c1 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+CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(Br)c1 +COc1cc(-c2ccc(Cl)c(C)c2)c(C)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CN1CCC(Cc2cnc3ccc(C#CCNC(=O)c4cncn(Cc5ccc(F)c(F)c5)c4=O)cc3n2)CC1 +CCC(N)C(=O)NC1C(=O)N2C(CCC1COC(C)=O)CCC2C(=O)NC(c1ccccc1)c1ccccc1 +COc1ccc(Nc2ncc3c(n2)-c2ccc(C#N)cc2NC(=O)C3)cc1OC +O=S(=O)(NCCN1CCC(Cc2c[nH]c3ccc(F)cc23)CC1)c1ccccc1 +O=S(=O)(c1ccccc1F)C1(F)CCN(CCc2ccc(F)cc2F)CC1 +Cc1ccc(-c2nc(CCCCC3COC(C)(C(=O)O)OC3)c(C)o2)c(C)c1 +O=C(C=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)Nc1ccc(F)cc1[N+](=O)[O-] +O=C(O)C(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C1OCOC1C(=O)Nc1ccccc1F +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc3c(c2)CCN3C)cc1 +CCCc1c(OCCCCOc2ccc(C(=O)O)cc2)ccc2c(-c3ccccc3)noc12 +Oc1cccc(-c2cc(NCc3cccnc3)nc(N3CCOCC3)n2)c1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccccc3)o2)C(C)O)c(C)c1Cl +Cc1c(NC(=O)C(C)Br)cccc1C(=O)NC(N)=O +C=COC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)CCCCNC(=O)OCc1ccccc1)C(C)C +Cc1cccc(-c2cc(NCCN3CCOCC3)c3ccccc3n2)c1 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+CCCC(NC1CCc2ccccc2N(CC(=O)O)C1=O)C(=O)O +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(C)NC3CCCC3)c2=O)c1F +CNc1nnc(-c2cn3ncnc(Nc4cnc5[nH]c(C)cc5c4)c3c2C(C)C)o1 +C=C1C=C(C)CC(C)(C)C1Cc1cc(OC)c(Br)cc1O +COc1ccc(C(=O)C(Cc2cccc(OC)c2)=C(C(=O)O)c2ccc3c(c2)OCO3)cc1 +COc1ccc(C(=O)c2ccc(=O)n(-c3cccc(C)c3)c2)c(O)c1 +CCC(C)C(N)CN(C(=O)C1CC1c1cccc(F)c1)c1ccc(-c2ccccc2)cc1 +Cc1ccc(Nc2nc(C(=O)N3CCC(C)CC3)cs2)cc1 +Cc1cccc(-c2nc(NCc3cccc(C#N)c3)sc2-c2ccc3ncnn3c2)n1 +CCOC(=O)c1sc2nc(CC(=O)NNC(=S)Nc3ccccc3)[nH]c(=O)c2c1C +O=C(CN1CCC(N2C(=O)OCc3cc(Cl)ccc32)CC1)Nc1ccc(C(=O)c2ccccc2)cc1 +Cc1c(C)n(Cc2ccc(-c3ccccc3C(=O)O)cc2)c2ccc(C(=O)NC(C)c3ccc(OC(C)C)cc3)cc12 +CC(C)c1onc(COc2ccc(Cl)cc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +CS(=O)(=O)Nc1cccc2c(O)cc(C(=O)Nc3ccccc3F)nc12 +CNCCN1CCC(OCc2ccc(C(F)(F)F)cc2)CC1 +CCN(CC)c1nc2ccc(NC(=O)c3c(C(=O)N4CCC4)cnn3C)cn2n1 +Cc1cc(C(=O)O)nn1Cc1cc(Br)ccc1OCc1cccc([N+](=O)[O-])c1 +COc1cc(-c2cn(CC(=O)N3CCC(c4nc5ccccc5o4)CC3)nn2)ccc1-n1cnc(C)c1 +COc1ccccc1-c1csc(Nc2ccc(Oc3ccccc3)cc2)n1 +O=C(Cc1ccccn1)N1CCc2nc(-c3cc4ccccc4[nH]c3=O)[nH]c2C1 +CCCN(CCCON1C(=O)CC2(CCCC2)CC1=O)C1COc2cccc(OC)c2C1 +C=CC1(C)CCC(C2=CCC(C(C)(C)O)OC2)CC1C(=C)C +O=C(O)CN1C(=O)C(=Cc2ccc(OCCc3ccc(OC(F)(F)F)cc3)c(OCc3ccccc3)c2)SC1=S +CC(C)(C)n1c(-c2ccccc2C(=O)NC2CCNCC2)nc2cc(-c3cnc(N)nc3)ccc21 +CNC(=O)NC1CCCN(C(=O)c2ccc(NC(=O)c3ccccc3C)cc2)c2ccccc21 +CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C(=O)N1CCS(=O)(=O)CC1 +O=C(O)CCN1CC=C(c2ccc(OCCCc3ccccc3)cc2)CC1 +CCc1ccc(NC(=O)N2CC(CC#N)(n3cc(C(N)=O)c(Nc4ccccc4)n3)C2)cc1 +Clc1ccc(-c2nn(Cc3ccccc3)nc2-c2ccc(Cl)cc2Cl)cc1 +CCCCc1ccc(-n2[nH]c3c(cnc4ccccc43)c2=O)s1 +NC(C(=O)NC(Cc1ccc(Cl)cc1)C(=O)N1CCN(C2(CNC(=O)Cc3ccccc3)CCCCC2)CC1)c1ccccc1 +O=C(c1ccc(Br)cc1NS(=O)(=O)c1cccc2nccnc12)N1CCOCC1 +O=C(c1nn(C2CCC(O)CC2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +O=C(Nc1cccc2c1C(=O)c1c(-c3ccc(C(=O)NCCN4CCCCC4)s3)n[nH]c1-2)NN1CCOCC1 +Cc1ncc(C(CNC(=O)c2cccc(OC(F)(F)F)c2Cl)N2CCC(F)(F)CC2)cn1 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+O=C(O)CCCCCCN1C(=O)CCC1C=CC(O)c1cccc(-c2cccc(Cl)c2)c1 +O=[N+]([O-])c1cc2c(O)c(-c3cc(F)cc(F)c3)c(O)nc2cc1Cl +O=C1c2ccc(-c3ccc(C(F)(F)F)cc3)cc2CCN1CCN1CCCC1 +CCOC(CO)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +COc1cc(-c2cn(C3CC(C(C)(C)C)CCN(CC(C)(C)C)C3=O)nn2)ccc1-n1cnc(C)c1 +Cc1cccc(-c2nn(C(=S)Nc3ccccc3)cc2-c2ccc3nc(C)nn3c2)n1 +COc1ccc(-c2ccc(CN(CCC3CCN(Cc4ccc(C)cc4)CC3)C(=O)NC(C)(C)CO)cc2)cc1 +Cc1cc(Nc2cc(C(F)(F)F)c(Cl)cn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1 +CC(=O)Nc1cccc(Nc2cc(NC3CC3)n3ncc(C#N)c3n2)c1 +COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(N3CC4(CCOC4)C3)c2n1 +COC(=O)CN(c1ccc2nc(C)n(Cc3ccc4ccc(C(=N)N)cc4c3)c2c1)C1CCN(C(C)=N)CC1 +COc1ccc(-n2nnc(-c3ccc(S(=O)(=O)NC(Cc4c[nH]c5ccccc45)C(=O)O)cc3)n2)cc1 +C=CC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3)nc3[nH]ccc23)c1 +CC1CCCCN1CCCNc1ncc(C(=O)NCc2ccccc2)c(NC2CCCC2)n1 +O=c1c2ccccc2nc(C=C(O)c2ccccn2)n1-c1ccccc1Cl +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(NC(=O)NCCC3CCCN3C)sc2c1 +COc1ccc(CC(CN(O)C=O)C(=O)NC(C(=O)N(C)C)C(C)(C)C)cc1 +N=C(N)c1ccc(CNC(=O)C2C=CCN2C(=O)C(CC2CCCCC2)NCC(=O)O)cn1 +O=C(Nc1ccc(-c2ccccc2)cc1)c1cc(I)cc(I)c1O +O=S(=O)(Nc1ccccc1)c1ccc(-c2nccnc2Cc2ccccc2)cc1 +Cc1cc(-n2cnc3c(NCC4CCOCC4)cc(Oc4cccc(F)c4)cc32)ccc1C(=O)NC1CC1 +Clc1cncc(Cl)c1NN=Cc1ccccc1-c1c(Cl)cccc1Cl +CC(=O)OCC12CCC(=O)C=C1C1(C)C=C(C#N)C(=O)C(C)(C)C1CC2 +CC(NCC(O)C(Cc1ccccc1)NC(=O)c1ccc(N2CCN(C)CC2)cc1)c1ccc(O)c(CN2CCCCC2)c1 +O=C(O)C1CN(CCNc2nc3ccccc3n(C3CC4CCC(C3)N4C3CCCCCCC3)c2=O)CC1C(=O)O +CCCCOc1nc2c(c(Nc3ccc(C(F)(F)F)cc3)n1)CCN(c1ncccc1C(F)(F)F)CC2 +CC(C)CC(NC(C(=O)NCc1ccccc1)c1c(C(=O)NO)[nH]c2cc(Cl)ccc12)C(=O)NO +O=c1cc(C2CCCCC2)oc2ccc(OCCCCCCN3CCCCC3)cc12 +Cc1cccc(NC(=O)c2nc(C)ccc2Nc2cccnc2)n1 +COc1cc(C(=O)NC2(C(=O)NC(C)c3ccc(-n4[nH]c(=O)c5ccccc54)cc3F)CC2)on1 +CC(=O)c1ccc(-c2cnc(N)nc2-c2c[nH]c3ccc(Br)cc23)cc1 +NS(=O)(=O)c1c(F)c(F)c(SCCc2ccccc2)c(F)c1NC1CCCCCCCCCCC1 +NC(=O)COc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2 +COc1ccc(CN2C(=O)CNC(c3ccccc3F)(C(Oc3nc(C)cc(C)n3)C(=O)O)c3ccccc32)cc1 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+CCCC(C)CNC(=O)c1ccc2c(c1)c(Cc1ccc(C(=O)NS(=O)(=O)c3ccccc3C)cc1OC)cn2C +CCOCCC1(Oc2ccc(Oc3ccc(-c4nc5ccccc5[nH]4)cc3)cc2)C(=O)NC(=O)NC1=O +O=C(Nc1cc(-c2cc3c([nH]2)C2(CCCNC2)CNC3=O)ccn1)c1ccc2ccccc2c1 +CNC(=O)c1cccc(F)c1Nc1nc(Nc2ccc3c(c2)NC(=O)C(NC(C)=O)CC3(C)C)ncc1Cl +CC(C(c1ccc2cc(OCc3ccc(OCC(=O)O)cc3)ccc2c1)n1ccnc1)N(C)C +CCCn1c(=O)c2nc(C3Cc4ccccc4C3)[nH]c2n(CCC)c1=O +CCc1ccc2[nH]cc(C(=O)CCC(C)(C)C)c(=O)c2c1 +O=c1c2ccccc2sn1-c1ccc(S(=O)(=O)N2CCOCC2)cc1 +CC(C)(O)CN1CCC(N(c2ccc(C#N)cc2)c2cccnc2)CC1 +CC(C)(C)NC(=O)NC1CCC(CCN2CCc3ccccc3C2)CC1 +CCCN(CCCc1c[nH]c2ccc(F)cc12)C1COc2c(F)ccc(C(=O)NC)c2C1 +O=C(NCCOCCO)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +C=CC(=O)Nc1cccc(-n2c(-c3nc(-c4cnn(C)c4)cnc3N)nc3ccccc32)c1 +CC(=O)c1ccc(NC(=O)CSc2nnc(-c3ccoc3C)n2Cc2ccco2)cc1 +CCc1ccc(-c2nc(CCOc3ccc4c(c3)CCC4C(CC)C(=O)O)c(C)o2)cc1 +O=C1C(=Cc2ccc(OCCN3CCCC3)c(Cl)c2)Oc2cc(O)ccc21 +COCC(C)Oc1cc(C=Cc2ccccc2OC)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 +CN1CCN(c2ccc(-c3cccc(OCC(O)CN4CCc5ccccc5C4)c3)cn2)CC1 +Cc1sc2nc(Cc3cccc(C(F)(F)F)c3F)cc(=O)n2c1C1CC1CO +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ncc(NC(=O)OCc2ccccc2)c1=O)C(=O)C(F)(F)F +C=C1C(=O)C23C4OC(C)(C)OC25OCC2(C(=O)C=CC(C)(C)C2C5O)C3CCC14 +O=C(c1ccc(F)cc1)N1CCN2C(=O)c3ccncc3C12c1ccc(Cl)cc1 +O=C(NCC1CN(c2ccc(N3CCCC3=O)c(F)c2)C(=O)O1)c1ccc(Cl)s1 +COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2ccc(F)cc2)CC1 +CNC(=O)c1nn(C)cc1NC(=O)c1nc(C2CC2)ncc1Nc1cncnc1 +COc1cc(NCCN2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)C)n1)CCN2 +COc1c(-c2cn[nH]c2)ccc(C(=O)NC(CO)c2c(F)cccc2F)c1F +O=C(NS(=O)(=O)c1cccc(C(F)(F)F)c1)c1cc2ccccc2n1Cc1cc(Cl)ccc1Cl +Cc1ccc2c(N3CCN(CCc4cccc5c4OCc4nnnn4-5)CC3)cccc2n1 +CCCCCCOCCCCCCCCCc1cc2cn(C3CCC(CO)O3)c(=O)nc2o1 +Cc1cccnc1-c1cc(Oc2ccc(S(C)(=O)=O)cc2)cc(C(=O)Nc2nc(CN3CCOCC3)cs2)c1 +CC(C)c1csc(NC(=O)C2c3ccccc3Oc3ccccc32)n1 +CC(C)Cc1ccc(C(C)C(=O)NCCOc2ccc3ccc(=O)oc3c2)cc1 +O=C(NC(c1ccccc1)c1ccccc1)c1cc(-c2ccccc2)nc2ccccc12 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(S(N)(=O)=O)cc3Cl)CC2)ncc1Br +CC(NC(=O)c1ccc(C#Cc2cccc(F)c2)cn1)C(C)(C)F +CCCCN(CCCc1ccc(O)c(OC)c1)C(S)=NCCc1ccccc1 +Cc1cc2[nH]c(=O)c3cnn(C4CCOCC4)c3c2cc1C(=O)N1CC(N(C)CCC(F)(F)F)C1 +NS(=O)(=O)c1ccc(F)cc1NS(=O)(=O)C=Cc1ccc(Br)cc1 +Cn1cc(Nc2ncc3c(n2)-c2c(nn(C)c2Cc2cccc(C(F)(F)F)c2)CC3)cn1 +CCc1nc(C2CC2)nc2c1CN(c1ncnn3c(C)nc(-c4ccccc4F)c13)CC2 +Cc1cc(C)nc(N2CC3CCN(C(=O)c4c(F)cccc4-n4nccn4)CC32)n1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3ncc(F)cc3F)cs2)CO1 +CCCCCc1ccc(C#CC(O)(c2ccc(C#N)c(-c3cccc4ccccc34)c2)c2cncn2C)cc1 +Cc1c(CC(=O)O)c2ccsc2n1Cc1ccc(S(=O)(=O)N2CCOCC2)cc1 +CCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)ncn3Cc2ccccc2)cc1 +Cc1cccc2c1N(CC1CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC1)C(=O)C2(C)C +COCCCOc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(Cl)c(C(F)(F)F)c4)ccc3C)CC2)ncn1 +CC1(C)N=C(N)N=C(N)N1OCCCCOc1cccc(C(=O)C=Cc2ccccc2)c1 +Cn1c(=O)cc(Nc2ccc(F)cc2F)c2cnn(-c3ccc(F)cc3F)c21 +CN1CCC(OC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 +COc1ccc(NS(=O)(=O)c2ccc3c(c2)c2cc([N+](=O)[O-])ccc2n3C)c(OC)n1 +O=C(O)CCc1ccccc1C(=O)N1C(=O)CCC1c1nc(C(=O)NCCCCC2CCCCC2)co1 +CC(Nc1nccc(-c2c(-c3ccc(F)cc3)nc3cc(CN(C)CCCN(C)C)ccn23)n1)c1ccccc1 +NC(=O)Nc1ccc2c(c1)C(=Cc1cc(C(=O)O)c[nH]1)C(=O)N2 +CCc1cn(C2CC(O)C(CNC(=O)Cc3ccccc3Cl)O2)c(=O)[nH]c1=O +Cc1ccc(NC(=O)CSc2snnc2-c2ccc(Br)cc2Br)c([N+](=O)[O-])c1 +Cc1ccc(-c2noc(C(C)Nc3nccc(N4C(=O)OCC4C(C)C)n3)n2)cc1 +Oc1ccc2c(Cc3c(Cl)cncc3Cl)nnc(-c3ccccc3)c2c1 +COc1ccc(Oc2c(Cl)cnn(-c3cccc(C(F)(F)F)c3)c2=O)cc1 +CN1CCCCC1CC(=O)N1c2ccccc2C(=O)Nc2cccnc21 +CN1C(=S)OC(C)(C)c2cc(-c3ccc(C#N)[nH]3)ccc21 +Cc1ccc(C2CC2COc2cc(NCc3cnn(C)c3)c(=O)n(C)n2)nc1 +CN(C(=O)c1ccc(OCC2CC2)cc1)C1Cc2ccc(CNCC3CCOCC3)cc2C1 +C#CC(CC)(CC)Nc1nc(NC)nc(-n2cncn2)n1 +CCOC(=O)CC(=O)Nc1scnc1C(=O)Nc1nccs1 +COc1ccc2cc(C(O)C(C)N3CCN(Cc4ccccc4)CC3)ccc2c1Cl +O=C1C2Cc3ccccc3CN2C(=O)N1CCCN1CCN(Cc2ccccc2)CC1 +O=S(=O)(c1cccc(Cl)c1)n1cc(Cl)c2cc3c(cc21)CCNCC3 +COC(CNc1cc(Oc2c(C)cc(C#N)cc2C)cc(Nc2ccc(C#N)cc2)n1)OC +NCCS(=O)(=O)NC(=O)c1ccc(Nc2nc(NC3(c4ccc(Cl)cc4)CC3)nc(OCC(F)(F)F)n2)cc1 +COc1ccc(N2Cc3c(nc(C)c(CN)c3-c3ccc(Cl)cc3Cl)C2=O)cc1 +O=C(Nc1ccc(-c2noc(CNCC3CCCO3)n2)cc1)N1Cc2ccccc2C1 +CC(C)(C)c1ccccc1S(=O)(=O)c1ccc(C(C)(O)C(F)(F)F)cc1 +NS(=O)(=O)Oc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1 +N#Cc1cccc(C2=Nc3cc(N4CCS(=O)(=O)CC4)c(C#Cc4ccccc4)cc3NC(=O)C2)c1 +Cc1ccc(C(=O)Nc2ccc(Cl)cc2)c(NC(=O)c2sc3ccccc3c2Cl)c1 +Cc1cccc2cc(C#N)c(SCC(=O)N3CC(=O)Nc4ccccc43)nc12 +Cc1ccc(-n2cc3c(n2)c(NC2CCCCC2)nc2ccccc23)cc1 +O=C(NC(CO)CO)c1ncncc1Nc1ccc(I)cc1F +CC(=O)OCC(Cc1ccccc1)NC(=O)C(Cc1ccc(O)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21 +CCOC(=O)N1C2CCC1CC(c1c(C)cnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn13)C2 +COC1COCCC1NC1CC2CN(C(C)=O)CC2(C(=O)N2CCc3ncc(C(F)(F)F)cc3C2)C1 +Cc1ccccc1-c1nccnc1C1CN(c2ncc3ccccc3n2)C1 +C=CCC12CCC(O)CC1=CCC1C2CCC2(C)C(O)CCC12 +NC(=O)n1cc(CC(=O)N2C(C(=O)Nc3cccc(OC(F)(F)F)c3)CC3CC32)c2cc(OCCO)ccc21 +Cc1cccc(Cl)c1NC(=O)c1ccc(-c2cc(Cl)ccc2Cl)o1 +NC(=O)c1ccc(Nc2ncc(Br)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +CCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(F)c4)c3)nc2n(C)c1=O +CCCCCCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1F +O=C(O)Cc1ccc(-c2cnc(N3CCOCC3)c3nc(COc4ccc5ccccc5n4)cn23)cn1 +NCC1OC(OC2C(CO)OC(OC3C(O)C(N)CC(N)C3OC3OC(CN)C(O)C(O)C3N)C2O)C(N)C(O)C1O +Clc1ccc(Nc2nnc(-c3cccc4cnccc34)c3ccccc23)cc1Cl +CCOc1ccc2c(c1)cc(CN(C(C)=O)C1CCCC1)c1nnnn12 +CCc1ccc(C2OC(COC(=O)OCC3CC4CCC3C4)C(O)C(O)C2O)cc1Cc1ccc2c(c1)OCCO2 +O=C(Cc1ccc(-c2ccccc2)cc1)Nc1nc2nn(CCc3ccccc3)cc2c2nc(-c3ccco3)nn12 +O=C(O)C1CCN(Cc2cc3nc(O)c(O)nc3cc2Br)CC1 +CCC1(c2ccc(CSc3ccc(Br)cc3)cc2)Oc2ccccc2-n2cccc2C1=O +CSc1ccc(CNC(=O)c2ccc(C(C)(C)C)cc2)cc1 +Cc1cc2c(cc1Cc1ccc(C(=O)NCc3cccc(CNc4nccc(C(F)(F)F)n4)c3)o1)C(C)(C)CCC2(C)C +COc1ccc(C(=O)C=Cc2ccc(CN3CCCCC3)c(O)c2)cc1 +COc1ccccc1-c1ccc(OC2OC(CO)C(O)C(O)C2O)c(Cl)c1 +Nc1ncc(CNC(=O)C2CCCN2C(=O)C(N)C(c2ccccc2)c2ccccc2)s1 +N#Cc1cccc(-c2ccc(C(=C3CCN(CC4CC4)CC3)c3nc4cc(F)c(F)cc4[nH]3)cc2)c1 +O=C(Nc1cccc(OCc2ccc(-c3cc(F)c(F)c(F)c3)cc2)c1)C1CCNCC1 +O=C(Nc1ccc(C2CCN(C(=O)C3CC3)CC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F +c1ccc(-c2ccc(Cc3cncc4ccccc34)cn2)cc1 +CC1(C)CCC(C)(C)c2nc(C(=O)Nc3ccc(C(=O)O)cc3)cnc21 +CCCCCCOP(=O)(O)C1=CC(OC(CC)CC)C(NC(C)=O)C(NC(=N)N)C1 +Cc1ccc(C(=O)Nc2cccc(N(C)C)c2)cc1Nc1ncnc2cnc(N3CCCCC3)nc12 +N#Cc1cnc2cnc(NCCN3CCOCC3)cc2c1Nc1ccc(Sc2ccccc2)cc1 +CCCn1c(=O)c2nc(-c3cnn(Cc4noc(-c5ccccc5Cl)n4)c3)[nH]c2n(CCC)c1=O +Cn1c(=O)c2c(CC(=O)Nc3nc(-c4cccc(C(F)(F)F)c4F)cs3)coc2n(C)c1=O +O=C(c1nn(C2CCCN(CC3CCOC3)C2)c2c1CS(=O)(=O)c1ccccc1-2)N1CCOCC1 +CN(C(=O)c1ccc(-c2ccc(F)cc2)cc1)C1CCc2cc(CN3CCS(=O)(=O)CC3)ccc2C1 +CNC(=O)Cn1cc2nccc(Nc3cc(-c4cc(C)ccc4F)ncc3C)c2n1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3cccc(C(=O)NC4CCOCC4)c3)nc2n1 +COc1cc(OC)nc(Sc2cccc(C(C)=O)c2C(=O)O)n1 +NS(=O)(=O)OCC1CC(Cc2cc(NC3CCc4ccccc43)ncn2)CC1O +Cc1cn(-c2ccc3n(c2=O)CCN(CCOc2ccc(F)c4nc(C(F)(F)F)sc24)C3=O)cn1 +Cn1cnc(S(=O)(=O)N(Cc2ccc(-c3cccc(S(C)(=O)=O)c3)cc2)Cc2c(F)cccc2Cl)c1 +CS(=O)(=O)N1Cc2cc(Cl)ccc2-n2c(nnc2C2CCN(c3ccccn3)CC2)C1 +CCC(C)OC(=O)C(C)NP(=O)(OCC1OC(C#N)(c2ccc3c(N)ncnn23)C(C)(O)C1O)Oc1ccccc1 +COc1ccc(C(=O)c2ccc3c(-c4ccc(OCC(=O)O)cc4)nocc2-3)cc1 +O=C(CCOc1ccc(CN2CCCCC2)cc1)N1CCC(Cc2c[nH]cn2)CC1 +O=C(Nc1ccc(-c2nnc(NCCCCN3CCCOCC3)o2)cc1)c1ccccc1F +OCC1OC(n2ccc3c(-c4cc5ccccc5o4)ncnc32)C(O)C1O +O=C(OCCc1ccccc1)c1cc(NCc2cc(O)ccc2O)ccc1O +COc1cccc2cc(C(=O)Nc3c(C#N)ncn3-c3ccc(F)cc3)c(=N)oc12 +CC(c1ccccc1)N1C(=O)C(CC(=O)N2CCC(N3Cc4ccccc4NC3=O)CC2)SC1c1ccccc1 +CCCCCCCCCCC(O)C1CCC(C2CCC(C(O)CCCCCCCCCCC(O)CC3=CC(=O)OC3C)O2)O1 +O=c1nc[nH]c2cc(-c3cnc4nc(N5CCC(N6CCCCC6)CC5)oc4c3)ccc12 +CCOC(=O)c1cc(-c2sc(-c3cccnc3)nc2-c2ccccc2)n[nH]1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1cc(F)c(Cl)cc1-c1cn[nH]c1 +N#Cc1cc(S(=O)(=O)Nc2ccc(F)cn2)ccc1Oc1cccc(F)c1F +CC1(C(=O)NC(Cc2cccc(F)c2)C(=O)O)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)n1 +CC1C(=O)N(Cc2ccccc2)c2ccccc2C(C)N1C(=O)NCc1ccccc1 +NC1CCC(Nc2ncc(Cl)c(-c3cccc(NCc4cccc(F)c4)n3)n2)CC1 +[C-]#[N+]C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1[S+](C)[O-] +CCCCc1nc(Cl)c(CO)n1Cc1cccc(C(=O)c2ccccc2C(=O)O)c1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC1(c2ccccc2)CCN(C(=O)c2ccc(F)c(F)c2)CC1 +CCOC(=O)c1nc(-c2ccc(NC(=O)Nc3ccc(NC(C)=O)cc3)cc2)nc(N2CCOCC2)c1OCC +CC1(C(=O)NC(Cc2ccc(C(F)(F)F)cc2)C(=O)O)CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CC#CC(CC(=O)O)c1ccc(OCc2ccccc2-c2ccccc2)cc1 +N#Cc1cc(F)ccc1-c1noc(CCC(=O)Nc2ccc3c(c2)c2ccccc2n3CCF)n1 +CCN(CC)CCOc1ccc2c(c1)C(C)(C)c1oc3cc(F)ccc3c1C2=O +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1C2Cc3[nH]ncc3C1CC(c1ccc(-c3cncs3)cc1)C2 +CN1CCCC1Cc1c[nH]c2ccc(C3=CCN(C(=O)Nc4cccc5ccccc45)CC3)cc12 +O=C(C=Cc1cccn(CCCc2ccc(Cl)cc2)c1=O)NO +COc1cccc(CN2CCC(NC(=O)c3cc(=O)c4ccc(F)cc4o3)CC2)c1 +COc1ccc(-c2nc(COc3cc(OC)cc4oc(-c5cn6nc(C)ccc6n5)cc34)cs2)cc1 +Cn1cc(-c2ccc3ncc4ccc(=O)n(-c5ccc(F)c(Cl)c5)c4c3c2)cn1 +COCc1ccc(Cn2ccc3nc(-c4ccccc4F)nc-3c2)cc1 +C=CC(=O)Nc1c(F)cccc1Nc1cc(N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)ncn1 +COc1ccc2c(Cc3c(Cl)cncc3Cl)n[n+]([O-])cc2c1OC1CCCC1 +COCCC1(Oc2ccc(Oc3ccc(-c4nc(-c5cccc(F)c5)co4)cc3)cc2)C(=O)NC(=O)NC1=O +O=C(C=Cc1cnccc1-c1cn[nH]c1)Nc1ccc(CN2CCOCC2)cc1 +NCCCC1NC(CNC(=O)C=Cc2ccc(Br)cc2)CCN(CC(c2ccccc2)c2ccccc2)C1=O +Cc1cc2c(cc1Cc1ccc(C(=O)NCC3CCC(CNc4nccc(Cl)n4)CC3)o1)C(C)(C)CCC2(C)C +CC(C)(C)c1nc(-n2ccc(=O)[nH]c2=O)c2ccc(-c3ccc(NS(C)(=O)=O)cc3)cc2n1 +CC(CCN1CCOCC1)CC(=O)Nc1ccc(C(=O)Nc2nccs2)cc1 +O=C(NCCn1cccn1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CNC(=O)C12CC1C(n1cnc3cnc(C#Cc4ccc(F)c(F)c4)nc31)C(O)C2O +CCCCc1cn(-c2ccccc2C(C)C)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1 +COC(c1ccc(Cl)cc1)(c1ccc2cnccc2c1)c1cncn1C +O=C(O)CC(c1cccc(-c2ccc3c(c2)OCCO3)c1)c1nccs1 +Brc1cc2c(NC3=NCC4(CN5CCC4CC5)O3)ncnn2c1 +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1-c1cc(-c2ccccc2)on1 +O=C(CC1CCCCN1c1cc(-n2ccnc2)ncn1)NCc1ccc2c(c1)OCO2 +CC(C)c1ccc2[nH]c(O)c(N=NC(=O)c3cccc(S(=O)(=O)N4CCCCC4)c3)c2c1 +COc1ccc(OCc2cccc(C(=O)O)c2)cc1Cc1cnc(N)nc1N +Cc1nn(Cc2ccc(-c3nc4ccc(C(F)(F)F)cc4[nH]3)cc2)c(C)c1CC(=O)O +COc1c(O)ccc2c1cnc1c3cc4c(cc3ccc21)OCO4 +CNC(C)C(=O)NC1COc2c(C(=O)N3CCN(CCO)CC3)cccc2N(Cc2ccc(Br)c3ccccc23)C1=O +O=C(NCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +N#CN=C(NCC12CC3CC(CC(C3)C1)C2)Nc1cccc2ncccc12 +COc1cc2c(N)nccc2cc1CC(C(=O)O)N1CCC(NS(=O)(=O)c2cnc(N(C)C)c(C)c2)C1=O +CC(C)(C)NC(=O)NC(Cc1c[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1 +O=C(CC1(c2ccc(C(F)(F)F)cc2)C2CC3CC1CC(C2)C3O)N1CC(O)C1 +Cc1cc(C2=NNC(=O)CC2C)ccc1N=C1CCCC(O)=C1Cc1ccccc1 +CN(C)Cc1ccc(-n2nc(C(=O)N3CCOCC3)c3c2-c2ccccc2S(=O)(=O)C3)cc1 +COc1cc2ncnc(Oc3ccc(NC(=O)NC(=O)c4ccccc4C)cc3)c2cc1OC +CCC(O)C#Cc1csc2c(NCC(N)Cc3ccccc3)nc(-c3ccncc3)nc12 +CC(Oc1ccccc1)C(=O)N1CCN(C(=O)c2cc(COc3ccccc3C(N)=O)ccc2F)CC1 +COc1cccc(Nc2cc(-c3cccc(-c4cccc(C(=O)NC5CC5)c4)c3)nc3c2C(=O)NCC3)c1 +Oc1ccc2c(c1)C13CCN(Cc4ccccc4)C(C2)C1(O)Cc1cc2ccccc2nc1C3 +CCn1c(=O)c2c(nc(COc3ccccc3)n2C)n(CC)c1=O +O=C(C1CCCN(c2ccc3nc(-c4cncc(C5CC5)c4)[nH]c3n2)C1)N1CCCC1 +Cc1ccc2ccc(C(Nc3cccnc3)c3ccccc3F)c(O)c2n1 +COc1cc(Oc2ncnc3ccn(C)c23)ccc1NC(=O)Nc1cccc(C(F)(F)F)c1 +O=C(Nc1cccnc1)C1CCCN1c1nc(Nc2cc(C3CC3)[nH]n2)c2cccn2n1 +Oc1ccc(C2CC2CN2CCN(c3ccc(Cl)cc3Cl)CC2)cc1 +Cc1cc(OCC(C)(C)C(=O)O)ncc1-c1ccc(-c2ncc(C3(C(F)(F)F)CC3)[nH]2)c(F)c1 +CC(C)C(NC(=O)C(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)C(=O)NCc1ccccn1 +Oc1ccc(OCC(O)CNC2CCN(c3ncnc4scc(-c5ccccc5)c34)CC2)cc1 +Nc1ncc(-c2cnn(CCCN3CCC(O)C3)c2)c2scc(-c3ccc(NC(=O)Nc4cccc(F)c4)cc3)c12 +Cc1ccccc1CCNCc1cccc(COc2nn3c(C(F)(F)F)nnc3c3ccccc23)n1 +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)cc1-c1ccc(Cl)cc1 +CNC(=O)c1cc(C)nc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)c1 +O=c1c(OCc2ccc(Cl)cc2)c(-c2ccccc2)oc2cc(O)cc(O)c12 +COc1ccccc1OCCN1CCN(c2cnn(CCCN3CCN(c4ccccc4OC(C)C)CC3)c(=O)c2Cl)CC1 +CCNCC#CCCC(=O)C(O)(c1ccccc1)c1ccccc1 +C#Cc1cccc(Nc2nc3c(-c4nnc[nH]4)cccc3c3cnccc23)c1 +CNC(=O)CNC(=O)Nc1nc2ccc(-c3cncc(S(=O)(=O)NC(C)(C)C)c3)cn2n1 +O=C(c1ccc(F)cc1)N1CCN(Cc2ccc(-c3ccc(F)cc3)[nH]2)CC1 +CC1(C)Oc2ccc(-c3cc(F)cc(Cl)c3)cc2C2(COC(N)=N2)C12COC2 +Cc1cccc2c1nc(COc1ccc(Cl)cc1)n2CCCC1CCN(CCC(C)C)CC1 +CC(=O)NC1(c2ccccc2)CCN(CC2CC2(C(=O)N(C)Cc2ccc(F)cc2)c2ccc(Cl)c(Cl)c2)CC1 +COc1cc(C=Cc2nc3n(n2)CCCC3c2cc(F)c(F)c(F)c2)ccc1-n1cnc(C)c1 +CCCn1nc([N+](=O)[O-])c(C(C#N)c2nc3ccccc3s2)c(Cl)c1=O +Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)CCCO2 +O=c1[nH]c2ccccc2n1C1CCN(Cc2csc3ccccc23)CC1 +CN1C(=O)C=CC2(C)C3CCC4(C)C(C(N)=O)CCC4C3CCC12 +Cc1c[n+](CC(N)=O)ccc1C=Cc1cccc2ccccc12 +Oc1ccc2c(c1)C1(CCCc3ccccc3)CCN(CCc3ccc(F)cc3)CC1O2 +CCOC(=O)C1=CCCCC1S(=O)(=O)Cc1cccc(Cl)c1 +CCCS(=O)(=O)c1nc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)cc(OC)n1 +Cc1cc2c(c(=O)o1)C=C1CCC(C(C)CNCc3ccc(O)cc3)CC1O2 +O=C1C=C(NCCCNc2ccnc3cc(Cl)ccc23)C(=O)C=C1NCCCNc1ccnc2cc(Cl)ccc12 +CCCn1cc(C(=O)c2ccc(OCC)c3ccccc23)c2ccccc21 +CCN1CCc2cc(O)cc3c2C1Cc1ccc(O)c(O)c1-3 +O=c1cc(-c2ccc(CN3CCCCC3)cc2)oc2ccccc12 +O=C1CSC(=O)N1CCCCCCCCNCC1CCc2ccccc2O1 +CC1(O)CCC(Nc2nccc(-n3ccc4c(N5CCC(S(C)(=O)=O)CC5)cccc43)n2)CC1 +Cc1cnc(-c2cc(Cl)ccc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c(NCCO)n1 +CCn1c(C)c(C)c2cc(-n3ccccc3=O)nc(NCc3c(C)cccc3C)c21 +CC1C(=O)NC(Cc2ccc(F)cc2)C(=O)NCCCCCOCCNC(C2CC2)C(=O)N1C +CN1CCCN(C(=O)c2cc3c(F)cccc3[nH]2)CC1 +CC(C)(O)CNC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(F)cc2Cl)n(-c2ccccc2)n1 +N#Cc1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc1 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+CN(C)c1nc(NCc2ccc(NC(=O)c3ccc(F)cc3)cc2)c2ccc(C3CC3)cc2n1 +Nc1nc(N)c(-c2ccc(NC(=O)Cc3ccsc3)cc2)c(COCc2ccccc2)n1 +O=C(O)Cc1cccc2c(NCc3cccc(-c4ccnc5c(C(F)(F)F)cccc45)c3)cccc12 +O=C(NC1C(=O)N(c2ccccc2)C1c1cccnc1)c1ccc(Cl)s1 +OCC1OC(n2cnc3c(NC4CC5CCC4C5)nc(Nc4ccccc4)nc32)C(O)C1O +COc1cc(-c2cc(OCC3(CC#N)CC3)c3cccnc3c2)cc(OC)c1OC +N#CC1(n2cc(C(NC(=O)c3ccccc3)C3CCCCC3)nn2)CC1 +CC(C)CN(Cc1cc(Cl)c2c(c1)OCCCO2)C(=O)C1CCN(Cc2ccccc2C(F)(F)F)C1 +COC1CCC(C(=O)N2CCC(N3CCN(C(=O)c4cc(-c5ccccc5)nc(-c5ccccc5)c4)CC3)CC2)CC1 +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(CC(N)=O)ccc3N2)c(O)c2ccccc21 +COc1ccc(C(NC(=O)c2ccc3cnccc3c2)C2CCNCC2)cc1F +NS(=O)(=O)OCC1OC(n2cnc3c(NCc4cccc5ccccc45)ncnc32)C(O)C1O +COc1cc2c(N)nccc2cc1CC(C(=O)O)N1CCC(NS(=O)(=O)c2cnc(N(C)C)s2)C1=O +CCCNc1cc(NC(=O)c2cccs2)cc(C(F)(F)F)c1 +CS(=O)(=O)c1ccc(-c2c[nH]c3ccc(-c4nnc(N)o4)cc23)nc1 +CC(C)N(C)C1CCN(c2nc(-c3ccc(C(=O)NC4(C(=O)NCC#N)CCCCC4)cc3)cs2)CC1 +COc1cccc(S(=O)(=O)N(C)c2ccc(Oc3ccccc3)cc2)c1 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+O=C1N(Cc2ncoc2-c2ccccc2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCC3Cc4ccccc4N3)cc12 +CC(C)NC(=O)c1cnn2ccc(N3CC(O)CC3c3cccc(F)c3)nc12 +CCN1CCN(CCS(=O)(=O)c2ccc(-c3cc4ncn(C)c(=O)c4c(NCCCO)n3)cc2)CC1 +Fc1ccc(CCCCN2C3CCCC2c2c([nH]c4ccccc24)C3)cc1 +Cc1cc(N2CC(C)NCC2C)nc2ccc(NC(=O)COc3ccc(OC(F)(F)F)cc3)cc12 +CC1=C2CCc3cc(C=Cc4ccccc4)ccc3N2CCC1=O +CC1CCN(c2nc(C(C)(C)C)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +OCC(O)C1C2CCC(CC2)C1Nc1nc(-c2c[nH]c3ncc(F)cc23)ncc1F +CCN(CC)CCCN(CC)CCCNc1ccnc2cc(Cl)ccc12 +COc1ccc(C2C(C(=O)O)C(c3ccc4c(c3)OCO4)CN2CC(=O)N(CC(C)C)CC(C)C)cc1 +CCn1ncc2c(-c3cncc(Br)c3)c(C#N)c(C)nc21 +O=C(Cc1ccccc1)N1CCNC2CCCC(N3CCCC3)C21 +O=C(Nc1ccccc1F)C1=C(O)CCn2c1nc1ncccc12 +COc1cc(C(C)C)c(Oc2cnc(NC(C)(C)CO)nc2N)cc1I +O=C1C(=O)N(Cc2ccccc2)c2ccc(S(=O)(=O)N3CCC3)cc21 +O=C(c1cccc(C(F)(F)F)c1Cl)N1C2CCCC1c1nnc(-c3cccnc3)n1C2 +COc1cccc(N2CN(CCc3ccccc3)CN=C2S)c1 +COc1ccc(S(=O)(=O)N2CCN(Cc3nc4cccc5c(=O)[nH]nc([nH]3)c45)CC2)cc1 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+Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCN1CCCCC1 +CC(C)c1cn(-c2nc(C(=O)O)cs2)c2cc(Cl)ccc12 +O=C(Nc1cccc(Br)c1)c1ccc(N2CCCC2)c(C(F)(F)F)c1 +Cc1c(OCCCCCN2CCC(O)CC2)ccc2c(=O)cc(-c3ccccc3)oc12 +CCCCC(CC)OC(=O)CCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +O=C(O)COc1cccc2cc(CCNCC(O)c3cccc(Cl)c3)[nH]c12 +COc1cccc(-c2cccc(C3(C)CSCC(N)=N3)c2)c1 +O=C(C1CNCCC1(O)c1ccc(F)c(F)c1)N(Cc1cn(Cc2cccc(OC(F)F)c2)c2cccc(F)c12)C1CC1 +CC(C)(C)OC(=O)Nc1cc(CN2C(=O)N(c3ccc(SC(F)(F)F)cc3)C(=O)C2(C)C)ccn1 +CCC(=O)N(c1ccccc1)C1(C(=O)OCCF)CCN(CCc2ccccc2)CC1 +CCCc1c(OCCCOc2ccc(OCC(=O)O)cc2)ccc2c(-c3ccccc3)noc12 +Cc1nc(NCc2nnc(C)s2)cc(OCC2CC2c2ccc(C3CC3)cn2)n1 +CSC(N)=NC(=NS(=O)(=O)c1ccc(Cl)cc1)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +N=C1NC23C(C4NC(=N)N2CC(OS(=O)(=O)O)(CC2C(CO)CON2C4=O)C3(O)O)N1COC(=O)NO +CCCN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(c3ccc(Br)cc3)=NN12 +CCC(CC)(CNC(=O)C1CCN(Cc2ccc(F)cc2)CC1)c1ccc(F)cc1 +CCCC(C)COc1ccc(C(CNC(=O)C(N)CC2CC2)NC(=O)C(C)c2ccccc2)cc1 +O=C(O)CCC(=O)NC(CC(=O)O)Cc1ccc(-c2cccc(F)c2)cc1 +COc1ccccc1C(=O)Nc1cc2c(cc1N(C)C)n(C)c(=O)n2C +CC(C)Oc1cc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)ccc1F +O=C(NC1CCc2cccc3c2N(C1=O)C(C(=O)O)C3)C(S)Cc1ccc(-c2ccccc2)cc1 +c1ccc2nc(N3CCC(Oc4nccnc4C4CCOCC4)C3)ccc2c1 +Cc1cn(CC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)nc1C +COc1ccc(N2CC(C)NC(C)C2)cc1NS(=O)(=O)c1ccc(-c2cccs2)cc1Cl +Cc1ncoc1-c1nnc(SCCCN2CCc3cc4nc(CC5CC5)oc4cc3CC2)n1C +NCc1ccccc1-n1nc(C(F)(F)F)cc1C(=O)Nc1ccc(-c2ccccc2S(N)(=O)=O)cc1 +CC1CN(c2sc(Br)nc2-c2nc3ccccc3[nH]2)CCN1C(=O)Cn1cnc2cccnc21 +CC(C)(C)OC(=O)N(C(=O)c1ccccc1)C1=NC(C)(c2nc(Br)ccc2F)CC(C(F)(F)F)O1 +CCc1ncnc(-c2cc(F)c(C(=O)N3CCN(C4COC4)CC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCC1OC(c2ccc(Cl)c(Cc3ncc(-c4ccoc4)cn3)c2)C(O)C(O)C1O +O=C(C=Cc1cccnc1)c1ccc(-c2ccccc2)cc1 +CC(C)(O)C1CCC(Nc2ccc3ncc(-c4cccc(F)c4)n3n2)CC1 +c1cc(OCCN2CCSCC2)cc(-c2nc(N3CCOCC3)c3oc4ncccc4c3n2)c1 +CNC(c1cccc(O)c1)C(C)(C)C(=O)NCCc1ccccc1 +O=C(C=Cc1ccc(O)c(O)c1)OC(C(=O)O)C(OC(=O)C=Cc1ccc(O)c(O)c1)C(=O)O +Cc1cc(C)c(C=C2C(=O)NN=C2c2snnc2C)[nH]1 +Fc1ccc(CNc2ncnc3c2cnn3CC(Cl)c2ccc(Cl)cc2)cc1 +COC(C)(C)C1CCCN1c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +CC(c1cccc(NC(=O)c2ccc(N3CCCC3)cn2)c1)N1CCC(C(=O)NC2CCCCC2)CC1 +COc1ccc(C(NC(=O)c2ccc3cnc(NC4CC(O)C4)nc3c2)c2cnn(C)c2)cc1F +CN1C(Nc2nc3ccccc3s2)=NCC12CN1CCC2CC1 +NC(CC(=O)NC1(c2nnc(-c3ccccc3)o2)CCS(=O)(=O)CC1)Cc1cc(F)c(F)cc1F +O=C(Nc1ccc(Oc2cncc(C(=O)NCCN3CCOCC3)c2)cc1)Nc1ccc(Cl)c(C(F)(F)F)c1 +COc1ccccc1Cc1c2c(nn1C)CCc1cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc1-2 +CCOc1cc(N2CCN(C)CC2)ccc1Nc1nc(N)n(C(=O)NCc2ccccc2S(=O)(=O)C(C)C)n1 +O=C(Nc1cccc2cnccc12)NC1CCc2cc(F)ccc2C1Cc1cccs1 +CCCCC(Sc1nc(OCCc2ccc(C(F)(F)F)cc2)cc(OCCc2ccc(C(F)(F)F)cc2)n1)C(=O)O +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc3c(c2)OCC3)cc1 +CN(c1ccnc(Nc2cccc(CO)c2)n1)c1cccc2[nH]ncc12 +FCCc1ccc(C2(c3cccs3)CC3c4ccccc4C2c2cccc[n+]23)s1 +CC(C)C(c1ccc2c(cnn2-c2ccc(F)cc2)c1)C(C)(C)C(=O)Nc1nncs1 +Cc1cccc(CNc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +CN1Cc2cc(CN3CCOCC3)ccc2C(c2cc3ccccc3s2)C1 +CCCCCCN1NN=C(NC(=O)Nc2c(C(C)C)cccc2C(C)C)N1 +CC1=CC(C)(C)Nc2ccc3c([nH]c4ccccc43)c21 +COc1cc(Cl)ccc1-c1cc(OC)c(-n2c(=O)ccc3cc(S(=O)(=O)Nc4ccon4)ccc32)cc1F +CCOC(=O)C1=C(C)NC2=C(C(=O)C(C(=O)OC)C(C)C2)C1c1cc(Br)c(OC)c(OCC)c1 +Cc1ccc2c(c1)[n+]([O-])c(NCCN1C(C)CCCC1C)n[n+]2[O-] +CCC(C)C(NC(=O)c1cccc(CN)c1)C(=O)NC(CCc1ccccc1)C(=O)CO +COCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N2CCCC2)c1=O +CNC(=O)C(NC(=O)C(CCc1ccccc1)CP(=O)(O)Cc1ccc(Cc2ccccc2C)cc1)C(C)(C)C +NC(=O)Cn1cc(-c2ccc(N3CCC(N4CCc5ccc(F)cc54)CC3)nn2)cn1 +NCCCNCCCCNCCCNCc1ccc(OC2=CC(=O)c3ccccc3C2=O)cc1 +CCn1ncc2c(NC3CCOCC3)c(C(=O)N3CCCC3)cnc21 +Cc1cc(C(=O)Nc2ccccc2)c2ccc(-c3ccc(OCC(C)(C)C(=O)O)[n+]([O-])c3)cc2n1 +CC(C)(C)c1cc(NC(=O)Nc2cccc(Cl)c2Cl)n(-c2ccccn2)n1 +Cc1c(O)cccc1C(=O)NC(Cc1cc2ccccc2s1)C(O)CN1CC2CCCCC2CC1C(=O)NC(C)(C)C +CC(C)CC(NC(=O)C(Cc1cccc2ccccc12)NC(=O)N1CCOCC1)B(O)O +Cn1c(-c2ccco2)nc2c(NC(=O)Cc3ccccc3)ncnc21 +Cc1ccc2[nH]cc(C(=O)OCC34CCN(CC3)CC4)c2c1C +CCCCCCC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(CCNCC(O)COc3ccc(O)cc3)cc2)cc1 +CCC(NC)C(=O)NC(C(=O)N1CC2Cc3cc(Cl)ccc3N2CC1C(=O)NC1CCOc2ccccc21)C1CCCCC1 +Cc1nc(N2CCN(C(=O)C3CCCC3)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +c1ccc(COc2ccc3c(c2)CCN(C2CCCC2)CC3)cc1 +CCC1CS(=O)(=O)c2cc(C(=O)N=C(N)N)c(C)cc21 +CC12CCCOC1C1(COC(N)=N1)c1cc(-c3cccnc3F)ccc1O2 +CC(C)(C)OCC(=O)NC1CC2CN(c3ccc(OC(F)(F)F)cc3)C(=O)N2C1 +CCCC(CCC)C(=O)Nc1cc(Cl)c(S(N)(=O)=O)cc1S(N)(=O)=O +COc1cc2[nH]c(-c3ccccc3)c(C=O)c2cc1-c1cnco1 +Cc1[nH]nc2c1C(=NN=C(N)N)CC(c1ccccc1Cl)C2 +O=C1CN2Cc3cc(OCCCC(=O)N4CCCCC4)ccc3N=C2N1 +COc1ccc(NNC(=O)C(=O)c2c[nH]c3ccccc23)cc1 +O=C(O)c1ccc(C2=CC3(CCNCC3)Oc3ccccc32)cc1 +O=C(Nc1ncc(CCO)s1)N1CCC(c2noc3ccc(F)cc23)CC1 +CC(C)(C)c1ccc(C(=CC(=O)Nc2ccc3c(c2)OCCO3)c2ccc(Cl)cc2)cc1 +O=S1(=O)CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +CCC(CC)C(N)CCN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1 +NNC(=O)c1cn(-c2ccc(S(N)(=O)=O)cc2)nc1-c1ccc(Br)cc1 +CCCC(C)n1c(CC)nc2c(-c3ccc(O)nc3C(F)(F)F)ccnc21 +COc1ccc(C(=O)CSc2nc(CN3CCCc4ccccc43)c(C)c(=O)[nH]2)cc1 +O=C1CC2(CCN(C(=O)Nc3ccc(C(F)(F)F)cc3)CC2)Oc2c(Cl)cccc21 +Cc1cc(CN2CCN(CO)CC2)ccc1C(=O)Cn1ccc(OCc2ccccc2)cc1=O +O=C(Nc1cc(N2CC(F)(F)C2)cc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)cc1F +O=C1NC(=O)C2=C1c1cn(c3ccccc13)CCCOC(CO)CCn1cc2c2ccccc21 +CN1OC2(N=C1N)c1cc(C3CC3)ccc1CC21CCc2ccccc2CC1 +N#CC(Cc1ccc(-n2cc(COC(=O)N3CCCC3)nn2)cc1F)NC(=O)C1NC2CCC1C2 +[N-]=[N+]=NCc1ccc(C(=O)CC(=O)C(=O)O)cc1CN=[N+]=[N-] +Cc1c(Cc2ccc(C(=O)O)cc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCNC2=O +O=C(NCCS(=O)(=O)c1ccc(C(F)(F)F)cn1)c1ccc(Br)cc1F +CC(C)(C)C(=O)NCCCCCN1CCN(c2ccc(Cl)cc2)CC1 +Fc1ccc(C=Cc2ccc(-c3ccc(Br)s3)s2)cc1 +O=C(CCN1CC=C(c2ccc(F)cc2)CC1)c1ccccc1 +O=C(O)CCCCn1nnc(-c2ccc(C(=O)N3CCC(N4CCC(Oc5ccc(Cl)c(Cl)c5)CC4)CC3)cc2)n1 +O=C(NCCCCN1CCCN(C(c2ccccc2)c2ccccc2)CC1)c1cc2ccccc2s1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(c3ncccc3C(F)(F)F)CC2)cc1 +NCCNCCNC(=O)COc1ccc2sc(CNc3nncc(-c4c(Cl)cccc4Cl)n3)nc2c1 +CN(C)CC(=O)NC(COc1cncc(-c2ccc3cnccc3c2)c1)Cc1c[nH]c2ccccc12 +CC1CCC(=O)N1c1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1 +O=C(Nc1cccnc1)C(=O)c1cc(Cc2ccccc2)n2ccccc12 +Cn1nnnc1-c1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1 +CC(C)Oc1ccc(Nc2ncc(CCC(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +O=c1c(-c2ccccc2F)cc(-c2ccccn2)cn1-c1ccccc1 +NS(=O)(=O)c1ccc(Nc2nc(F)nc(NCCO)n2)cc1 +CC1c2c(cc(F)c(-c3cccc4cc[nH]c34)c2F)NC(C)(C)C1OC(=O)Nc1ccc(N(C)C)cc1 +COC(=O)N1Cc2c(-c3ccc(F)cc3)ncn2-c2ccccc21 +OCC1OC(c2ccc(Cl)c(Cc3nnc(C(F)(F)F)s3)c2)C(O)C(O)C1O +Cc1ccc2c(c1)CCN2CC(=O)NC1CCC(CNS(=O)(=O)C(C)C)CC1 +COc1ccc(NC(=NC(=O)c2ccc(F)c(F)c2)NC2CCCCN(CC(=O)N3CCCC3)C2=O)cc1 +Oc1cccc(N2CCc3cc(O)ccc3C2c2ccc(N3CCN(CC4CC4)CC3)cc2)c1 +Cc1ccc2[nH]c(C(=NO)C3CCN(C)CC3)cc2c1 +NC(=O)C(c1cccc(F)c1)(c1cccc(F)c1)c1cccc(F)c1 +O=C(O)c1nc2ccccc2n(C2CC3CCC(C2)N3C2CCCCCCCCC2)c1=O +CC(N)C(=O)N1Cc2[nH]c3ccccc3c2CC1C(=O)O +O=C(NCc1ccc(F)cc1)c1cnc(Nc2cccc(Br)c2)cc1C(F)(F)F +Cc1ccc(-c2cn(-c3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)nn2)cc1Nc1nccc(-c2cccnc2)n1 +CC(=O)Nc1ccc(-c2ccc(N(Cc3cccnc3)C(=O)c3ccc(O)cc3O)cc2)c(C)c1 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+O=C(Nc1ccc(C(F)(F)F)cc1)NC1CCN(C(=O)CC(F)(F)F)CC1 +Cc1ccc2c(Nc3ccc(N4CCN(C)C(C)C4)cc3)c(C)c(C)nc2c1C +N#Cc1c[nH]c2ncnc(N3CCC(N)(CNC(=O)c4ccc(F)cc4F)C3)c12 +COc1cc(Nc2c(C#N)cnc3ccc(C=CCCN4CCOCC4)cc23)c(Cl)cc1Cl +Oc1nc2cccc(N3CCN(Cc4cc(-c5ccc(F)cc5)ccn4)CC3)c2o1 +Cc1cc(-n2ccnc2C)c2cccc(OCc3c(Cl)cncc3Cl)c2n1 +COc1cc2c(cc1OCCO)Nc1cc(-c3ccc([N+](=O)[O-])c(OC)c3)ccc1C(=O)N2 +CC(=O)c1ccc(NC(=O)NC23CC4CC(CC(C4)C2)C3)cc1 +Cc1cccc(NC(=O)OCc2ccc(-c3n[nH]c4c3Cc3cc(CN5CCN(C)CC5)ccc3-4)s2)c1 +CCN(CCCCCCNC1=CC(=O)C(NCCCCCCN(CC)Cc2cccc(OC)c2)=CC1=O)Cc1cccc(OC)c1 +CC1CN(c2cc(NS(=O)(=O)c3ccc(-c4cccs4)cc3)ccc2C#N)CC(C)N1 +Cc1c(Cc2cccc(NS(N)(=O)=O)c2F)c(=O)oc2cc(OC(=O)N(C)C)c(F)cc12 +CC(C)CC(NC(=O)C1CCNCC1)C(=O)NC(CCc1ccccc1)C(=O)c1nc2cc(S(N)(=O)=O)ccc2o1 +O=C1c2cc(OCCN3CCCC3)ccc2-c2ccc(OCCN3CCCC3)cc21 +Cc1cc(Cl)ccc1NC(=O)Nc1ccc(NS(N)(=O)=O)cc1 +CC(NC(=O)c1c(CN2CCC(N)CC2)c(-c2ccccc2)nc2ccccc12)C1CCCCC1 +CCN1CCN(c2cn(S(=O)(=O)c3ccc(F)cc3)c3ccc(Cl)cc23)CC1 +O=C(Cc1ccccc1)NCCCNCCCCNCCCNC(=O)Cc1ccccc1 +Cc1ccc2[nH]c(C(=O)NN(CC(C)C)c3nc(C#N)ncc3Br)cc2c1 +O=C(Nc1ccccc1-c1nc2cccnc2s1)c1cc(N2CCOCC2)nc(-c2ccccc2)n1 +CCCN(CCCNc1ccnc2cc(Cl)ccc12)Cc1cccc(F)c1O +NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CCc1ccc(-c2ccc(-c3ccccc3)cc2)cc1 +CN1C(=O)C(NC(=O)C(Cc2cscn2)NC(=O)OC(C)(C)C)N=C(c2ccccc2)c2ccccc21 +N#CC(Cc1ccc(N2CCNCC2)cc1F)NC(=O)C1NC2CCC1C2 +CCn1c(=O)c(-c2cc(C(=O)NC3CC3)cc(F)c2C)cc2nnc(-c3c(F)cccc3F)n21 +O=C(c1cccnc1)c1cc(-c2ccoc2)c2ccc(OCc3cccc(C4(O)CCOCC4)c3)cc2c1 +Cc1ccc(C(=O)NCc2cccc(C(C)(C)C)c2)cc1Nc1ncnc2cnc(N3CCCC3)nc12 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2ccc(C3(O)CCNCC3)nc2)c1 +CC(C)(c1nc(-c2cc(C(F)(F)F)cc3[nH]ccc23)nc2c1OCC1COCCN21)S(C)(=O)=O +CCOc1ccc(C2(CC(C)CCNCCCC(N)=O)CCC2)cc1 +Nc1ccc(Cn2cnc3c(Nc4cccc(N)c4)ncnc32)cc1 +CCOc1ccc2[nH]c(SCC(=O)Nc3ccccc3C(=O)OC)nc2c1 +CC(C)c1cc(-c2noc(NC(=O)C3CC3)c2-c2ccc(CN3CCSCC3)cc2)c(O)cc1O +O=C(CCCCCCC(=O)Nc1ccc(-c2ccccc2)cc1)NO +CN(C)CCC(CNC(=O)Nc1cc(F)cc(F)c1)c1ccc(-c2cccc(C#N)c2)cc1 +c1cc(OCc2ccc3ccccc3n2)cc(OCc2ccccc2-c2nn[nH]n2)c1 +Cc1c(N(Cc2cc(F)c(F)c(F)c2)S(=O)(=O)c2ccc(C(=O)O)cc2)sc2ccccc12 +CN1CCCCC1COC(=O)C(C)(c1ccccc1)c1ccccc1 +NS(=O)(=O)c1ccc2c(c1)sc1nc(-c3cc4cc(Cl)ccc4oc3=O)cn12 +COc1ccc(S(=O)(=O)N(Cc2ccccc2)Cc2ccc(C(=O)NCc3ccccc3)cc2)cc1 +O=C(c1cc(Cl)cc(Cl)c1)c1cc(Cl)ccc1OCCn1ccc(=O)[nH]c1=O +O=C(CCl)Nc1ccc(SCC(=O)Nc2ccc(Cl)cn2)cc1 +COc1ccc(C(Oc2ccc(Cn3c(N)nc4cc(-c5cnn(C)c5)cnc43)cc2OC)C2CC2)cn1 +CC(C)(CC(=O)Nc1ccc(F)c(F)c1)NCC(=O)N1CCCC1C#N +O=C(O)CCNc1sc2c(c1Cc1nnc(SCC(=O)NNC(=O)c3ccccc3)n1NC(=O)c1ccccc1)CCCC2 +Fc1ccc(-c2[nH]c(C=Cc3ccccc3)nc2-c2ccncc2)cc1 +COc1cccc(Oc2c(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)ncnc2OCCOc2ccccn2)c1 +Cc1cccc(Nc2nccc(-c3c[nH]c4ncccc34)n2)c1 +CC(C)(C[N+](C)(C)C)C1OC2CCCCC2C2C=CCCC21 +CCC(NC(C)=O)c1cc(Cl)ccc1C1CCN(C(=O)C2CN(C(C)(C)C)CC2c2ccc(F)cc2Cl)CC1 +COC(=O)C(C#N)=C(Nc1cccc2cc[nH]c12)NC1CCCCN(CC(=O)N2CCCC2)C1=O +CC(=O)N1CCCC1(Cc1ccc(F)cc1)C(=O)OCc1ccccc1 +CC1NC(=O)C2CC(F)(F)C(C)C(C=Cc3ccc(-c4ccccc4C#N)cn3)C12 +CCN(CCN)C(=O)c1cc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2cccc3ccccc23)ccc1C +NC1CC1c1ccc(NC(=O)c2ccc(N3CCOCC3)cc2)cc1 +Cc1ccc2c(c1)CN(S(=O)(=O)c1cccc(C(=O)O)c1)CC2 +CNC(=O)c1ccc(N2C(=S)N(c3cnc(C#N)c(C(F)(F)F)c3)C(=O)C23CCC3)cc1F +c1ccc(C(CCNC2=NCc3ccccc3CN2)c2ccccc2)cc1 +O=C(Nc1ccc(S(=O)(=O)C(F)(F)F)cc1)c1cnc(N2CCC(O)C2)c(-c2cncnc2)c1 +CC(NC(=O)c1cnc(-c2ccccn2)nc1)c1cccc(-c2noc(C(C)(C)O)n2)c1 +NS(=O)(=O)c1ccc(NN=C2C(=O)Nc3cccc(Oc4ccccc4)c32)cc1 +CN(C)CCn1c2c3c(n[nH]c(=O)c4cc(F)cc1c34)CC(C)(C)C2 +N#CSCC1CC(O)(c2ccccc2)CC(c2ccc(Br)cc2)O1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(Cl)cc1-c1ccnc(NC2CCC2)c1 +CN(C)c1ncc2c(n1)-c1ccc(Cl)cc1C(c1ccccc1F)=NC2 +CC1=C(C(=O)N2CCN(c3ccccc3)CC2)C(c2ccc(Cl)c(Cl)c2)n2nc(C)cc2N1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc3c(n2)NC(=O)CO3)c1F +Cc1ccc(F)c(NC(=O)Nc2ccc(-c3ccc(F)c4onc(N)c34)cc2)c1 +CN(CC(C)(C)N1CCc2c(-c3cnc(N)nc3)nc(N3CCOCC3)nc21)S(C)(=O)=O +CCCCCCN1CC2C(C1)C2(CCC)c1cccc(NS(C)(=O)=O)c1 +CN(C)C12CC(OC(=O)C=Cc3ccccc3)C(C(c3ccccc3)C1)C(c1ccccc1)C2 +CNCC(O)C(c1cccc(F)c1)n1ccc2ccccc21 +N#CC1CCCN1C(=O)C1CC(NS(=O)(=O)c2ccccc2)CN1 +CC1CCCN1C1CCN(c2ccc(NC(=O)N3CCN(c4ccccc4)CC3)cc2)C1 +c1ccc2c(c1)c1cnccc1n2CCCCCCCn1c2ccccc2c2cnccc21 +CN(C)C(=O)c1ccc(-c2cnc(N)c(C(=O)Nc3ccccc3)n2)cc1 +COc1cc(C(=O)c2ccccc2)ccc1-c1nc(C2CCC2)n2ccnc(N)c12 +O=S(=O)(Nc1ccc(CCNCC(O)COc2cccnc2)cc1)c1ccc(Cl)c(Cl)c1 +CC(=O)N1CC=C(c2nccnc2OC2CN(C(=O)c3cc(C)c[nH]3)C2)CC1 +CC(C)n1ccc2cc3c(cc21)CCN3C(=O)Nc1cccnc1 +Cc1ccc(-c2ncc(C(=O)NC(C(N)=O)c3ccccc3)nc2-c2ccc(C)cc2)cc1 +O=c1ccc2cnc3ccc(-c4ccsc4)cc3c2n1-c1ccc(N2CCNCC2)c(C(F)(F)F)c1 +Cn1nc(-c2cc(NS(C)(=O)=O)ccc2Oc2ccc(F)cc2F)c2cc[nH]c2c1=O +O=C(Nc1ccccc1)N1CCN(Cc2cnc3ccccc3c2)CC1 +c1ccc(-c2cc3ccncc3cc2OC2CCNCC2)cc1 +CNC(=O)N(C)CC#Cc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +CCCCN(C)S(=O)(=O)CC1CC(N(C)c2ncnc3[nH]ccc23)C1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1S(=O)(=O)CCO +Nc1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +Cn1cc(C2=C(c3cccs3)C(=O)NC2=O)c2ccccc21 +O=C(Nc1cc(Nc2cnccn2)nc(-c2ccnc(N3CCNCC3)c2)c1)c1cccnc1 +O=C1Nc2ccc(NC(=O)C(=O)N3CCC(Cc4ccccc4)CC3)cc2CO1 +COc1ccc(Nc2nc(Nc3ccc(OC)cc3)nc(NC(C)C)n2)cc1 +CCN1CN(C2CCC(CNCC(F)F)CC2)c2c(cnc3[nH]ccc23)C1=O +COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3ccccc3NC(=O)c3cnc4ccccc4c3)cc1)CC2 +O=C(O)c1ccc(-c2n[nH]c3c2Cc2cc(CNC4CCC(O)CC4)ccc2-3)cc1 +CCC(C)C(NC(=S)Nc1ccc(C(F)(F)F)cc1)C(=O)NC(Cc1ccccc1)C(=O)Nc1cccc(Br)c1 +Cc1ccc(NC(=O)c2cccc(C3(C#N)CC3)c2Cl)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)n1 +CCOC(=O)c1cnc(NN2C(=O)C=C(C)C2=O)nc1-c1ccsc1 +CCCCc1c(C(=O)NCc2cncn2CC(=O)O)cnn1-c1ncc(C)c(-c2cccs2)n1 +COc1cccc(-c2cn(Cc3c(F)cccc3F)c(=O)n(CC(N)c3ccccc3)c2=O)c1F +CCC(CC)N1CCn2nc(-c3ccc(Cl)cc3Cl)c3nc(C)cc1c32 +Cc1c(Cc2ccccc2)nnc(N2CCC(O)(c3ccc(C(C)(C)O)cn3)CC2)c1C +COC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1-c1ccccc1C(=O)NC(Cc1ccccc1)C(=O)OC +Cc1cc(Cl)ccc1C1c2c(nn(CCCO)c2C(C)C)C(=O)N1c1cccc(Cl)c1F +NS(=O)(=O)c1nnc(NC(=O)CNC(=O)OCc2ccccc2)s1 +CC(C)c1nnc2ccc(-c3ocnc3-c3ccc(Cl)cc3Cl)cn12 +COc1ccc(-c2sc(N)nc2-c2cc(OC)c(OC)c(OC)c2)cc1N +COc1cc(F)ccc1-c1nc(Nc2cc(CS(C)(=O)=NC#N)cc(C(F)(F)F)c2)ncc1F +O=C(c1ccc(O)c(O)c1)c1nccc2cc(O)c(O)cc12 +CC1=CSC(OCC(F)(F)F)(c2ccccc2)c2noc(=O)n21 +Cn1c(=O)c(S(=O)(=O)c2ccc(F)cc2F)cc2cnc(Nc3cccc4[nH]ccc34)nc21 +O=C(NCC1(c2ccc(Cl)cc2)CCOCC1)c1cccc(Cl)c1Cl +CC1CCC(Cn2c(C(C)(F)c3ccccc3F)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CC(=O)N1CC2CN(c3nc4ccccc4n(C4CCN(C5CCCCCCC5)CC4)c3=O)CC2C1 +CCCC(NC(=O)c1ccc(OC)c(Cl)c1)C(=O)OC +Cc1nc(-c2ccc(N(Cc3ccccc3)C(=O)c3ccc(O)cc3O)cc2C)c2ccccc2n1 +COc1ccc(CC(NC(=O)C(NC(=O)C(Cc2ccc(OC)cc2)NC(=O)c2ccc(F)cn2)C(C)C)B(O)O)cc1 +CCC(C)(C)C(=O)Nc1cc(CN2CCOCC2)c(C#N)cn1 +CCCCCCC(Sc1nc(Cl)cc(Nc2nc(-c3ccc(OC)cc3)cs2)n1)C(=O)O +N#Cc1ccnc(Nc2cc(C3CCN(C4COC4)CC3)cc(N3CCC(F)(F)C3)n2)c1 +COc1ccc(C=CC(=O)OC2C(O)c3c(cc(OC)c4c(=O)c5cc6ccccc6cc5n(C)c34)OC2(C)C)cc1 +Cc1cc(Sc2c([N+](=O)[O-])cc([N+](=O)[O-])cc2C(F)(F)F)c(Cl)cc1Cl +COc1cc(C=CC(=O)CC(=O)C=Cc2ccco2)ccc1O +CC(=O)Nc1cccc(C2CCN(CCCCCn3c(-c4ccccc4)nc4ccccc43)CC2)c1 +COc1ccc(-c2cnc3nc(N)nc(N4CCN(c5ccc(F)cc5)CC4)c3n2)cc1OC +COc1ccc2c(c1)nc(CCc1nc(-c3ccccc3)cn1C)n1nc(C)cc21 +CCOC(=O)Nc1cc2c(nc(SCc3ccc4c(c3)OCO4)n2N)c(N)n1 +CC(C)(O)c1cc(Nc2cc(C#N)ccn2)nc(N2CCC(F)(F)C2)c1 +CCCn1c(=O)c2nc(-c3cc(OCC(=O)N4CCN(c5ccc(F)cc5)CC4)nn3C)[nH]c2n(CCC)c1=O +CCCc1ccc(C2=CCN(CCOc3ccc(CC(OCC)C(=O)O)cc3)CC2)cc1 +CC12CC3CC(C)(C1)CC(C(=O)NNc1c(Cl)cncc1Cl)(C3)C2 +O=C(C1CCN(Cc2ccncc2)CC1)N1CCC(n2c(=O)n(Cc3ccc(Cl)cc3)c3ccccc32)CC1 +NCCC(=O)Nc1cccc2c1cnn2S(=O)(=O)c1cccc2ccccc12 +COc1ccc(C2=NN(C3CCN(C(=O)CN4C(=O)CCC4=O)CC3)C(=O)C2(C)C)cc1OCC1CC1 +Cc1cc(C(F)(F)F)c(-c2ccc(CC(NC(=O)c3c(Cl)cccc3Cl)C(=O)O)cc2)c(=O)n1Cc1ccccc1 +Cc1cc(OCc2nc(-c3ccc(N4CCCCC4)cc3)c(-c3ccc(OC(F)(F)F)cc3)s2)ccc1OCC(=O)O +Cc1cc(C(C)(O)C#Cc2ccc3c(c2)-c2nc(C(N)=O)c(C(=O)NCc4cccnc4)n2CCO3)no1 +CCC1Nc2ncnc(N3CCN(c4ccccn4)CC3)c2N(Cc2ccc(Cl)cc2)C1=O +CCCCCn1cc(C(=O)c2cccc3ccccc23)cc1-c1ccc(F)cc1 +CN(C)C1Cn2c(-c3ccnc(Oc4ccccc4)n3)c(-c3ccc(F)cc3)c(=O)n2C1 +C=CCN(CC(=O)O)C(=O)C(C)(C)Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1 +CC(C)Oc1ncccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(F)c12 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+Cn1c(-c2ccoc2)c(C2CCCC2)c2ccc(C(=O)O)cc21 +CS(=O)(=O)c1ccc(-n2nc(C(F)F)cc2-c2ccc(Cl)cc2)nc1 +Cn1c(=O)c(-c2ccccc2Br)cc2cnc(NCc3cccc(N)c3)nc21 +COC(=O)c1sccc1NC(=O)Cc1ccc2ccccc2c1 +O=C(Nc1ccc(F)c(F)c1F)NC1C2CC3CC(C2)CC1C3 +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c2cc(C2=CCCCO2)nc1F +CC(C)(NC(=O)c1ccc2c(c1)CCC1C2CCC2(C)C(c3cncc(F)c3)=CCC12)C(=O)O +O=C(Nc1c(F)cccc1F)c1cn(Cc2c(F)cccc2F)c2ccc(=O)[nH]c2c1=O +COCCCc1cc(CN(C(=O)C2CNCCC2c2cc(=O)n(C)c3cc(Cl)ccc23)C2CC2)cc(OCCOC)c1 +CC(NCc1ccccc1)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCc1ccccc1 +COc1ccc(CCNC(=O)C(=O)C(Cc2ccccc2)NC(=O)CCC(=O)c2cc(OC)ccc2OC)cc1 +COC(=O)C(F)(C1Cc2[nH]c3ccc(Cl)cc3c2C1)S(=O)(=O)c1ccccn1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5cccc(Cl)c5)CC4)cc3)cc2n(CCC)c1=O +CCc1ccccc1Nc1ncc(C)c(-c2c[nH]c(C(=O)NC(CO)c3cccc(Cl)c3)c2)n1 +N#Cc1ccccc1COc1nn2c(-c3ccccc3)nnc2c2c1C1CCC2CC1 +Oc1ccc2cccc(Nc3ncc(-c4ccc(C(F)(F)F)cc4)o3)c2c1 +O=C1NCCN1c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1 +Cc1cc2ccccc2n1CCNC(=O)C=Cc1ccc(OCCCO)cc1 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+CN1CC(c2cc(OCc3ccc(F)cc3)ncn2)=C(O)C1=O +COc1ccc2nc(Nc3nc(O)c4ccc(N(C)C)cc4n3)nc(C)c2c1 +Cc1[nH]c(C)c(-c2ccc(Oc3ccccc3)cc2)c(=O)c1Br +COc1ccc(-c2cccc3cnc(Nc4ccc(-n5cnc(N6CCOCC6)n5)cc4)nc23)cc1F +CC1CN(S(=O)(=O)c2ccc(C(=O)Nc3nc(-c4cc5ccccc5o4)cs3)cc2)CC(C)O1 +CN1CCCC1COc1cnc(Cl)c(-c2ccnc(F)c2)c1 +CN1CCN(C2CCN(C(=O)n3sc4c(ccc[n+]4[O-])c3=O)CC2)CC1 +O=C(C=Cc1ccc(O)cc1)CC(=O)C=Cc1cc(C(F)(F)F)ccc1F +Cn1nnnc1-c1cc(Br)cc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3)C2)c1 +Cc1cc2[nH]c(=O)c3cnn(C4CCOC4)c3c2cc1C(=O)N1CCC(OCC(F)(F)F)CC1 +COc1ccc(C2CCN(c3ccc(S(=O)(=O)C4(C(=O)NO)CCOCC4)cc3)CC2)c(C)c1 +COCCNC(=NC#N)N1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +O=C(CCCc1c[nH]nn1)NC1CCN(C(=O)OCc2cc(F)cc(Cl)c2)CC1 +CCC(C)CNCCc1c2c(nc3cc4c(cc13)OCCO4)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC +O=C1OCc2cc(CCC3C4CN(C(=O)Cc5ccc(-n6cnnn6)cc5)CC34)ccc21 +CN(C)Cc1nc(-c2ccc3[nH]nc(-c4cccc(C(=O)NCc5ccc(F)cc5)c4)c3c2)n[nH]1 +CC(CCOc1ccc(-c2ccc(Cl)cc2)cc1)CCN1CCN(c2ccncc2)C1=O +CCN(CC)CCOc1ccc(NC(=O)c2ccc(-c3ccccc3)cc2)cc1C(C)=O +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc4[nH]ccc4c3)nc2n1 +O=C(O)CCCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1 +CC(Nc1ncnc(N)c1C#Cc1cnc(N)nc1)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +CNC(=O)C1[Se]C(n2cnc3c(NCc4cccc(F)c4)nc(Cl)nc32)C(O)C1O +COC(=O)C1CCCN1C(=O)CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C +COc1c(C)c2c(c(O)c1CC=C(C)CCC(=O)NC(C)C(=O)O)C(=O)OC2 +COc1cc(C(=O)N2CC(OC)C2)ccc1Nc1cc2c(-c3cnn(C4CCN(C)CC4)c3)cccc2cn1 +O=C(Nc1ccc(Cl)c(C(=O)Nc2cccnc2)c1)c1cccc(F)c1 +Cn1ncc2c1Nc1ccccc1N(C(=O)CCCCCCCN1CCN(Cc3cc(O)cc(O)c3)CC1)C2 +O=C(O)C1(c2ccc3c(c2)CCC(C(c2ccccc2)C2CCCCC2)C3O)CCCC1 +N#Cc1ccc(-c2nc(N)c3cc(Cc4ccccc4)sc3n2)o1 +N#Cc1ccc(COc2ccc3c(c2)CCn2c-3cc(OCC3CCCO3)nc2=O)cc1 +CCc1cc(C(C#CC2CC2)(OC)C(F)(F)F)c(O)nc1C +CC(C)c1ccccc1-c1cc2cccc(NC(=O)Nc3ccc(C(C)(C)C)cc3)c2o1 +CN1CCC(N2CCC(Oc3nc(-c4ccncn4)cc(=O)n3C)CC2)CC1 +Fc1ccc(-c2nc(-c3ccccc3)[nH]c2-c2ncnc3[nH]cnc23)cc1 +CN1CCC(=C2c3cc(Cl)ccc3C=Cn3cccc32)CC1 +COc1ccc2c(c1)c(C(=O)C1C(C)(C)C1(C)C)cn2CC1CCOCC1 +CC(C)c1cccc(C(C)C)c1NC(=O)CC(=O)CCCCCCCCCCOC1CCCCO1 +CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)cnc2OCC2(O)CCCC2)cc1 +CCCN(CCC)[P+](CC)(N(CCC)CCC)N(CCC)CCC +CCCC1=C(C(=O)OCC)C(c2cccc([N+](=O)[O-])c2)C(C(=O)OCC)=C(C)N1 +CCNc1cc(C(=O)NC(Cc2ccccc2)C(O)CNC(C)CCCC(C)C)cc(N2CCCC2=O)c1 +Cn1ccc2ncnc(Oc3cccc(NC(=O)c4ccccc4)c3)c21 +Cn1cc(-c2ccncc2)c(-c2ccc(OCc3nc4ccccc4n3C)cc2)n1 +CCc1ncnc(-c2cc(F)c(C(=O)N3CCN(CCCS(C)(=O)=O)CC3)c(Cl)c2)c1C#Cc1ccc(N)nc1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(CN3CCNC(c4ccccc4)C3)c2)cc1 +CC(C)CCC(=O)N(C)Cc1ccccc1-c1ccc(CN2CC(C)NC(C)C2)cc1 +CC1CCCN1CCc1ccc(-c2ccc(CCC(=O)NC(C)(C)C(=O)OC(C)(C)C)cc2)cc1 +CC(C)C(NC(=O)C(CC(=O)O)NC(=O)CCCOc1ccc(C(=N)N)cc1)C(=O)N1CCN(C)CC1 +CCCCc1nc2cc(OC)c(OC)cc2c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cccc(C(CCc2ccccc2)NCC(O)Cc2ccc(O)c(NS(C)(=O)=O)c2)c1 +Cn1c(-c2ccc(Cl)cc2F)nnc1-c1ccccc1C(F)(F)F +O=S(=O)(Nc1ccc(Br)cc1)c1ccc2c(c1)CNC(CF)C2 +O=C(CC1C(=O)NCCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1)NC1CCCc2cc(CN3CCCCC3)ccc21 +C#CCNc1ncnc2c(Nc3ccccc3C)nc(N3CCNCC3)nc12 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NCc1cc(Cl)ccc1Cl +COc1cccc(C(=O)N(C)N=Cc2ccc(OC)c(OC)c2)c1 +CCCC(c1cc(C(C)(C)C)c(O)cc1C)c1cc(C(C)(C)C)c(O)cc1C +CCCCNc1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +Cc1ncnc(Nc2ccc(OCc3cccc(F)c3)c(Cl)c2)c1C#CC=NOCCN1CCOCC1 +COc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(C4(CCN5CCCC5)CC4)cc2)CC3)cc1 +CCN(Cc1ccncc1)C(=O)Cn1c(=O)n(C)c2cnc(-c3ccccc3)nc21 +C#Cc1cccc(Nc2ncnc3ccc(OCc4ccc(C(=O)Nc5ccccc5N)cc4)cc23)c1 +CNCC(Nc1ncnc2c(C(N)=O)cc(-c3ccc(C)cc3)cc12)C1=CCCC=C1 +O=C(Nc1ccc(Oc2ccnc3[nH]ccc23)c(F)c1)c1cccn(-c2ccc(F)cc2)c1=O +Cc1ccc(-c2c[nH]c(C3(NCCc4c[nH]c5ccccc45)CCCC3)n2)cc1 +Cc1n[nH]cc1-c1cccc2c1CCC2c1ncc[nH]1 +COc1cc(-c2nnc3n(C(C)c4ccc(F)cc4)cc(CF)cc2-3)ccc1-n1cnc(C)c1 +Cc1ccc(O)c(C2C(=O)NC(=O)N2c2ccc3[nH]cnc3c2)c1 +COc1cc(CN(CC2CCCCC2)C(C)c2ccc3c(c2)CCO3)ccc1OCCN1C(=O)CCC1=O +O=C(CN1CCOc2ccccc21)N1CCN(c2scnc2-c2nc3ccccc3[nH]2)CC1 +CCC(C)C(NCC(N)CS)C(=O)NCc1ccc(C)cc1C +N#Cc1ccc(OCc2ccsc2)cc1OC(C(=O)O)c1ccccc1Br +CCCCCNC(=O)Nc1cc(C=CC(=O)NO)ccc1SCCN(CC)CC +COc1ccccc1CC1=C(Nc2ccc(C3=NNC(=O)CC3C)cc2)CCCC1=O +OC(CNC1CCC(C(c2ccccc2)c2ccccc2)NC1)c1ccc(F)cc1 +CN1C(C(=O)NC(C=O)Cc2ccccc2)Cc2cc(F)ccc2S1(=O)=O +CC(CC(=O)O)N1CC(=O)N(C(C)(C)C)c2c(Cl)cc(C#Cc3ccc(C(=N)N)cc3)cc2C1=O +O=C(O)Cc1cnc(C(=O)c2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc2)c2ccccc12 +CC(C)C(C(=O)NC1CCC2CN(Cc3cccc(C(F)(F)F)c3)CC21)c1ccccc1 +CC(CC(N)=O)NC(c1ccc(Cl)c(C(=O)c2ccc(CO)cc2)c1F)C1CC1 +CCC1c2c(CO)ncn2-c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)nc2N1C1CCCC1 +CC(C)(O)CNc1ncc(C(=O)NC2C3CC4CC2CC(O)(C4)C3)c(C2CC2)n1 +CCCCN(c1cccc(-c2ccc(Cl)cc2)c1C)S(=O)(=O)c1ccc(OC(C)C(=O)O)c(OC)c1Cl +COc1cccc2c1CCC1CN(CCn3c(=O)[nH]c4c(C)c(C)ccc4c3=O)CC21 +CCCCCN(CCCCC)C(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1cnc2ccccc2c1 +CCOC(=O)c1ccc(-c2cc(=O)c3ccccc3o2)cc1 +CCCc1cnc(N2CCC(C3Cc4cc(C5=CCN(S(=O)(=O)CCCCO)CC5)cc(F)c4O3)CC2)nc1 +CCCCCC(O)C=CC1C(CC=CCCCC(=O)OC)C(=O)C(C)(C)C1O +Cc1ccc(Nc2c3ccc(N)cc3nc3cc(N)ccc23)cc1 +C[N+](C)(C)CC(=O)Nc1ccc2nc(O)c3ccccc3c2c1 +COc1cccc(OC)c1-c1ccc(CC(N=C(NCc2ccccn2)C2CCN2S(=O)(=O)c2ccccc2)C(=O)O)cc1 +Cc1ccc(S(=O)(=O)NC(=O)Cc2ccc(NCC(C)NCC(O)c3cccc(Cl)c3)cc2)cc1 +N#Cc1cc(-c2n[nH]c(-c3ccnc(C#N)c3)n2)ccn1 +CC(C)C1(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)CCC(NC2CCc3c(N)cccc32)C1 +O=C(NCc1ccc(N2C3CCCC2CC3)cc1C(F)(F)F)Nc1cccc2[nH]ncc12 +CC1=C(c2nc(-c3ccc(C#N)cc3)cs2)C(c2ccc(C(F)(F)F)nc2)NC(=O)N1 +CCCCc1nnc(S(C)(=O)=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1cc(OCC(=O)Nc2cc(-n3nc(C)cc3C)nc(-c3ccc(C)o3)n2)cc(C)n1 +CSc1[nH]c2cccc3c2c1CC1C3C=C(CO)CN1C +CN1c2ccccc2C(NCCCCCCC(=O)NCCCCNc2c3c(nc4ccccc24)CCCC3)c2ccc(Cl)cc2S1(=O)=O +CC(C)C(C)Nc1ccc(C(=O)O)cc1[N+](=O)[O-] +Cc1nccn2c(-c3ccnc(NCC(C)(C)C(=O)O)n3)c(-c3ccc(F)cc3F)nc12 +COCC(C)(O)CC1(c2ccccc2)CCN(C(C)c2ccc(-c3ccn(C)c(=O)c3)cc2)C(=O)O1 +Cc1cccc(-c2nc(Nc3ccncn3)c3ccccc3n2)n1 +Cc1ccc(C2=CC(c3ccc(N(C)C)cc3)n3nnnc3N2)cc1 +CC(Nc1ncc(F)c(N2C(=O)OCC2C(C)O)n1)c1cnc(C(C)(F)F)c(Cl)c1 +Cc1c(C)n(C(C)c2ccccc2)c2nc(-c3cnccn3)nc(N)c12 +N#Cc1ccc(OCc2ccc(F)cc2F)c(C2=C(c3cccc(C(=O)O)c3)CCC2)c1 +Cc1ccccc1OCc1ccnc2c1NC(=O)c1cccnc1N2C1CC1 +O=C(CN1CCC(N2C(=O)OCc3cc(Cl)ccc32)CC1)Nc1ccc2c(c1)-c1ccccc1C2=O +CN(C)c1ccc(NC(=O)c2cn(Cc3c(F)cccc3Cl)c3ccc(=O)[nH]c3c2=O)cc1 +CCCCN(C)Cc1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +CCC(C)C(CN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1)NC(C)=O +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)C(N)C(C)C)CC2)cc1 +COc1cc(OCc2csc(-c3ccc(OC(F)(F)F)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +C=CC(=O)NCCCn1c(NC(=O)c2cccc(C(F)(F)F)c2)nc2cc(C)ccc21 +CCn1c(-c2ccoc2)c(C2CCCCC2)c2ccc(C(=O)O)cc21 +O=C(N1CCC(CCSc2ncc[nH]2)CC1)C12CC3CC(CC(C3)C1)C2 +CCC(C)C(NCN(Cc1ccc(F)cc1)C(=O)c1ccc(F)cc1)C(=O)NC(Cc1cscn1)C(=O)NO +CC(=O)N1CCc2c(nc(C)n2C2CC3CCC(C2)N3CCCN(C(=O)Nc2ccc(F)cc2)c2ccccc2)C1 +Cc1ccc(S(=O)(=O)Nc2c(C(=O)NCc3ccc(C)cc3C)cnn2-c2ccccc2)cc1 +CN1CC(C(=O)N2CCC(C)(N3CCc4c(-c5cnc(N)nc5)nc(N5CCOCC5)nc43)C2)C1 +NC1CCN(C2CCC(NC3CC3c3ccc(-c4cccc(C(F)(F)F)c4)cc3)CC2)C1 +CCc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4c[nH]c5ccccc45)c3)cc12 +OC(c1ccc(Cl)cc1)(c1cccnc1)c1cnc(OC(CF)CF)nc1 +[N-]=[N+]=NCCCCCCCCCCCC(=O)OCC1OC(n2ccc(N)nc2=O)CS1 +CCC(=C(c1ccc(C=CC(=O)O)cc1)c1ccc2[nH]nc(C)c2c1)c1ccccc1 +Cc1ccc2ccccc2c1-n1c(C)nc2ccc(O)nc21 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(-c2ccccc2)c1 +CC(=O)c1ccc(N2CCN(C(=O)c3ccc(NC(=O)N4Cc5ccccc5C4)cc3)CC2)cc1 +C=CCNC(=O)OC(C)C1c2ccccc2-c2c3c(c4c([nH]c5ccccc54)c21)CNC3=O +Nc1ncnc2c1nc(Sc1ccc(Cl)cc1)n2C1OC2COP(=O)(O)OC2C1O +O=C(Nc1ccncc1)Nc1ccc(CCN2CCN(c3ccccc3)CC2)cc1 +Cc1c(OCc2cccnc2)ccc2c(N3CCNCC3)cc(=O)oc12 +CC1CN2c3c(cc4c(-c5nccnc5Cl)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +Cc1[nH]c2ccccc2c1CN(C)C(=O)C=Cc1cnc2c(c1)CCC(=O)N2 +CC(=O)Nc1ccc(-c2cccc(C(C)NC(=O)C3=C(O)C(=O)N(c4ccc(F)cc4F)C3)c2)cc1 +OC1OC(n2cnc3c(NC4CCCCC4)ncnc32)C(O)C1O +Cc1ccc(C(=O)NCCCOc2ccc(S(=O)(=O)C3(C(=O)NO)CCOCC3)cc2)c(C)c1 +CC(Oc1cccc(Cl)c1)C(=O)N(Cc1cccc(Cl)c1)CC1CCCN1 +Oc1ccc(C=Cc2cnc(OCCOCCOCCF)c(I)c2)cc1 +Cc1ccc(S(=O)(=O)n2cc(C(=O)C(=O)NCC(=O)O)c3ccccc32)cc1 +COc1cccc(-c2nc3c(c(Nc4ccc(CC(=O)O)cc4)n2)SCCC3)c1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(C(F)(F)F)cc1-c1ccncn1 +CC(C)CC(NC(=O)OCc1ccccc1)C(=O)NC(CC(C)C)C(=O)N1CCCC1B(O)O +CCOC(=O)c1ccc(NC(=O)NC(Cc2ccc(O)cc2)C(=O)NC2CCN(Cc3cccc(C#N)c3)C2)cc1 +CN1CCC(F)(COc2cccc3ccc(-c4nnc5ccccn45)nc23)CC1 +c1cnc2c(N3CCN(CCCCc4ccc(OCCCN5CCCCCC5)cc4)CC3)cccc2c1 +CC1c2c(ccc(O)c2F)OC(c2ccc(OCCN3CCCCC3)cc2)C1c1ccc(O)cc1 +O=c1cc(N2CCc3[nH]nc(-c4ccncc4)c3C2)ccn1Cc1cccc(F)c1 +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)Nc1cccc2cccnc12 +CC(C)(C)c1cc(NC(=O)Nc2ccc(N)cc2)n(-c2ccccc2)n1 +COc1cc2c(Nc3ccc(F)c(Cl)c3)c(C(N)=O)cnc2cc1OCCN(C)C +CC1SCc2ncnc(N3CCN(C(=O)C(N)Cc4ccc(F)cc4)CC3)c21 +CC(=NNC(=O)c1cc(Br)ccc1O)c1cc2c(F)c(F)ccc2[nH]1 +CCN(CC)c1ncnc2[nH]cc(-c3cccc(C#N)c3)c12 +Clc1ccc2nc(NCCc3ccc(NC4=NCCCS4)cc3)sc2c1 +Nc1ncnc2c1sc1nc(C3CC3)cc(C(F)(F)F)c12 +CN(Cc1ccc2nccnc2c1)C(=O)c1ccc(C(=O)C(F)(F)F)s1 +Oc1ccc2oc(-c3cccc(Cl)c3)cc2c1CN1CCC(N2CCCCC2)CC1 +COc1cccc(-c2[nH]c(-c3ccccc3)nc2-c2ccncc2)c1 +O=C(CCn1c2c(c(=O)[nH]c1=O)CCCC2)NCC(=O)c1ccc2ccccc2c1 +CC(=O)N(c1ccccc1)C1CC(C)N(C(=O)C=Cc2ccccc2)c2ccccc21 +CC(C(=O)NN=C1C(=O)Nc2ccc(C(=O)N3CCC(NC4CC4)CC3)c(Cl)c21)c1ccc(O)cc1 +O=C1CCCc2cc(Nc3cc(C(F)(F)F)ccn3)ccc2N1 +CC(CO)Nc1cc(NS(=O)(=O)c2ccc(C#N)cc2)nc(SCc2ccccc2)n1 +Fc1ccc(C#CCOc2nsnc2C23CN4CC2C3C4)cc1 +O=C1NC(=S)SC1=Cc1csc(-c2ccccc2O)n1 +CN(C)C(=O)c1nc(Nc2cccnc2Oc2ccccc2C(C)(C)C)sc1-c1ccccc1 +Cc1ccc2c(NCc3ccc(NC(=O)c4ccc(F)cc4)cc3)nc(NCCc3ccccn3)nc2c1 +O=C(Nc1ccc(F)cc1)Nc1ccc(CNc2nc3ccc(OCCN4CCOCC4)cc3s2)cc1 +OC1COc2cccc(Nc3cc(-c4ccc(C(F)(F)F)cc4)ncn3)c2C1 +Cn1cc(-c2cc(C(=O)Nc3nccs3)ccc2Oc2ccccc2)c2cc[nH]c2c1=O +O=C1CCc2ccc(NC(=O)NC3CCOc4cc(OC(F)(F)F)ccc43)cc2N1 +CCC(CO)Nc1nc(Nc2cccc(Cl)c2)c2ncn(C(C)C)c2n1 +Cc1cnccc1CCC(C)C1CCC2C34CCC5(CC(N(C)C)CC=C5C=C3CCC12C)O4 +CC(C)Nc1c([N+](=O)[O-])cnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12 +CCn1cc(Nc2nccc(-c3ccn(C(CO)c4ccc(Cl)c(F)c4)c(=O)c3)n2)c(C)n1 +COc1ccc(S(=O)(=O)N(Cc2ccc(-c3nnn[nH]3)c(F)c2)Cc2ccccn2)cc1 +COCC(C)Oc1cc(C=Cc2cccc([N+](=O)[O-])c2)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 +NC(Cc1ccc(O)cc1)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CO)Cc1ccccc1 +Cc1nc2cc3c(cc2[nH]1)C1(C)CCN(CC2CC2)C(C3)C1C +O=C(CSc1nc2c(c(=O)n1-c1ccccc1)SCC2)Nc1ncc(-c2ccco2)cn1 +N#Cc1cn(-c2c[nH]n(-c3cc(N4CCCOCC4)ncn3)c2=O)nn1 +CC(C)(C)c1ccc(CNC(=O)c2cn3cc(-c4ccc(C5CCC(CC(=O)O)CC5)cc4)ccc3n2)cc1 +Cc1ccnn1CC12CNCCC1(c1ccc(Cl)c(Cl)c1)C2 +CNc1ccc(C=Cc2ccc(OCCCCCCCCCCCCCCCCCCCCCCCCF)cc2)cc1 +CCN(Cc1ccc(-c2cc(OC(C)C3CNC(=O)C3)c3cccnc3c2)cc1)C(C)=O +CN1CC=C(c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Br)oc23)CC1 +COc1cc2c(-c3ccc(O)cc3)nc3c(c(C)nn3-c3ccccc3)c2cc1OC +COC(=O)N1CCN(C(=O)Cc2ccc(F)c(Cl)c2)C2C(N3CCC(F)C3)CCCC21 +Cc1ccc(C(=O)Nc2cccc(CN3CCC(C(=O)NC4CCCCC4)CC3)c2)cc1C +CC(C)(Oc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c3cc(F)ccc3n(CCC3CC3)c1=O)N2)C(N)=O +COc1cc(Nc2nc3n(n2)CCCN3CCC2CC2)ccc1-n1cnc(C)c1 +CCN(Cc1cc(C(F)(F)F)ccc1-n1cc(CC(=O)O)c2ccc(C)cc21)C(=O)C1CC1 +O=C(NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21)c1ccccc1 +CCOC(=O)c1ncn2c1Cn1ncnc1-c1cc(C3CC3)ccc1-2 +Cc1cc(C)cc(S(=O)(=O)c2c(C(=O)NCc3ccncn3)[nH]c3ccc(Cl)cc23)c1 +CC1=CC(=O)N(Nc2nc(-c3cccs3)nc3scc(-c4ccccc4)c23)C1=O +COc1cccc(C#N)c1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 +COc1ccnc(Nc2nc(-c3sc(C)nc3C)cs2)c1 +Cc1cnn(-c2cc(N3CC(c4nc5ccccc5n4C)C3)nc(C)n2)n1 +NC1(c2ccc(-c3nc4nc(OCCN5C(=O)c6ccccc6C5=O)ccn4c3-c3ccccc3)cc2)CCC1 +ON=C(c1ccc(Sc2cc(F)cc(C3CCOCC3)c2)cc1)C(F)(F)F +CC(=O)NC1C(NC(=N)NC(=O)CSc2cccc3ccccc23)C=C(C(=O)O)OC1C(O)C(O)CO +CC(C)S(=O)(=O)NC1COCC1c1ccc(-c2ccsc2)cc1 +C=CCn1c(=O)c2[nH]c(-c3ccccc3)nc2n(C)c1=O +CC(CCC(=O)NCCc1ccc(S(N)(=O)=O)cc1)C1CCC2C3CCC4CC(O)CCC4(C)C3CC(O)C12C +CN1CCN(CCn2cc(CNc3c4ccccc4nc4c3oc3ccccc34)nn2)CC1 +O=c1cc(NCc2ccc(C(F)(F)F)cn2)c2cc(C(c3ccc(Cl)cc3)c3ccc(Cl)cc3)ccc2[nH]1 +NC1=NC(c2ccncc2)(c2cccc(-c3cncnc3)c2)C2=NCCCN12 +COC(=O)COc1ccc2oc(=O)n(Cc3ccc(Cc4ccc(I)cc4)cc3)c2c1 +CC1(c2cc(NC(=O)c3ccc(Cl)cn3)cc(C(F)(F)F)c2)CCSC(N)=N1 +CCOc1c(Cl)cc(Cl)cc1CNCCCNc1nc(O)c2ccccc2n1 +Cn1cc(Nc2ncc(Cl)c(CCc3ccccc3C(C)(C)C(N)=O)n2)cn1 +O=C(Cc1ccncc1)N1CCN(C2c3ccc(Cl)cc3SCc3cccnc32)CC1 +CC(O)CN(CC(O)C(Cc1ccccc1)NC(=O)CC1C=CCC1)S(=O)(=O)c1ccco1 +Cc1cccc(Nc2ccc(C#N)cc2S(=O)(=O)NC(=O)NC(C)(C)C)c1 +CNc1cc(NC(=O)OC)ccc1Nc1c2c(nc3c1C=CCC3(C)C)CC(C)(C)C=C2 +COc1cc2ncnc(Nc3ccc4c(c3F)CCN4C(=O)Cc3c(C)[nH]c4ccccc34)c2cc1OC +CCCc1cc(OC)c(OC)c(C(=O)NCC2CCCN2CC)c1O +FCCc1ccc(-c2cn(C3CN4CCC3CC4)nn2)cc1 +CCCN=C1SC(=Cc2ccc(OCCO)c(Cl)c2)C(=O)N1c1ccccc1C +CCC(C)C1NCCOc2ccccc2CCCNC(=O)C(Cc2ccccc2)NC(=O)C(C)N(CC)C1=O +CN1CC(CNC(=O)c2ccccc2)CC2c3ccc(C(C)(C)C)c4[nH]cc(c34)CC21 +CCCS(=O)(=O)c1nccc(NC(Cc2ccc(NC(=O)c3c(Cl)cncc3Cl)cc2)C(=O)O)n1 +COc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Oc2cccc(C(F)(F)F)c2)CC1 +CC(c1ccc(-c2ccc(C#N)cn2)cc1)N1CCC(CC(C)(C)O)(c2ccccc2)OC1=O +Cc1cc(OCCN2CCCCCC2)nn1-c1ccc(Cl)c(Cl)c1 +N=C(Nc1cccc2ccccc12)N(c1ccccc1)c1cccc2ccccc12 +Cc1ccc(-c2noc(COc3ccc(CCC(=O)O)cc3)n2)cc1 +CCN1CCCC1CNC(=O)c1ccc(-c2cnc3ccc(NCC4CC4)nn23)cc1 +COc1ccc(N2C(=O)C(=Cc3ccc(O)c(Br)n3)OC2=S)cc1 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+N=C(N)NOCCNC(=O)Cc1c(Cl)ccc(NCC(F)(F)c2cccc3cnccc23)c1F +Cn1cc(-c2cnc3nnn(Cc4ccc5ncncc5c4)c3n2)cn1 +COc1ccc2c(c1)C(=O)N(CCc1ccc(S(=O)(=O)NC(=O)NC3CCCCC3)cc1)C(=O)C2(C)C +CCCCCCCOc1ccc(CCC(=O)OCC(O)COP(=O)(O)OCC(N)C(=O)O)cc1 +NC(=O)c1ccc2[nH]c(-c3ccc4[nH]c(-c5ccc6ccccc6c5)nc4c3)nc2c1 +OCCN1CCCC(c2nc3ccccc3n2Cc2ccc(F)cc2)C1 +O=C(Cc1ccccc1)NCc1ccc(-c2nc(C(=O)N3CCC(Cl)CC3)co2)cc1 +OC(CNC1CCC(C(c2ccccc2)c2ccccc2)OC1)c1ccc(F)cc1 +COCCN(Cc1ccccc1)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +CC(C)c1ncc(COCCCCCC#N)n1-c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +Nc1ccccc1NC(=O)c1ccc(CSC2=NC(c3cccnc3)CO2)cc1 +CNC(=O)c1cc(OC)cc(N(CC2CC2)c2ccc3ncc(-c4cnn(CCOC)c4)nc3c2)c1 +NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1cccc(NS(=O)(=O)N2CCCC2)c1 +COc1cc(CN2CC(C)OC(C)C2)cc2[nH]c(=O)c3c(c12)NCCC3 +O=C1CCc2ccccc2N1CCCN1CCC(c2ccc3[nH]ccc3c2)CC1 +O=C(Nc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1)c1cc(F)cc(C(F)(F)F)c1 +Cc1cc(NC(=O)c2ccc3cc4n(c3c2)C(C)CNC4=O)no1 +O=C(NCc1ccccc1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +Cc1nn(C)c2c1CN(c1ncnn3c(C)nc(C4CCOCC4)c13)CC2 +CS(=O)(=O)c1ccc(-n2nc(COc3ccc4c(c3)OCO4)cc2-c2ccccc2)cc1 +CCC1(CC)CNC(=O)c2cc(-c3ccncc3)[nH]c21 +CCCCn1cc[n+](CC(O)(P(=O)([O-])O)P(=O)(O)O)c1 +CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN(Cc2cccnc2)C(=O)c2ccccc2)cc1 +Oc1ccc(Nc2nc(-c3ccccc3)nc3ncccc23)cc1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3cc4ccccc4[nH]3)CC2)nc1 +COc1ccc(-c2ccc3c(O)oc(=O)c(C(=O)NCC(=O)O)c3c2)cc1 +CS(=O)(=O)c1ccc2c(c1)CCN2CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +CN1Cc2cc(-c3ccc(CC(C#N)NC(=O)C4CCCCN4)cc3)ccc2C1=O +COc1cc(NC(C)CCCNC2CCC3(CC2)OOC2(C)CCC(C(C)C)=CC2O3)c2ncccc2c1 +Oc1ccc2c(c1)sc1c3cc(O)ccc3n(Cc3ccc(OCCN4CCOCC4)cc3)c21 +CC(NC1CCC(N)CC1)c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1 +CC1COCc2[nH]c(-c3cc(C(=O)N4CCC(c5ccc(C#N)cc5)CC4)ccc3C3CC3)nc21 +CC(=O)NCc1ccccc1-c1ccc(COC2CCC(N3CCCCCC3)C2OCC=CCCC(=O)O)cc1 +CCCC1CC(OC)CC(C)=CC2CC(OC(=O)C(C)=CCCc3coc(C=CCNC(=O)OC)n3)CC(CC(=O)O1)O2 +O=C(NC1CCOCC1O)c1cc(NC(=O)c2cc(-c3ncccc3F)c(Cl)cc2Cl)n(-c2ccccc2)n1 +O=c1oc2cc(O)ccc2c(-c2ccc(OCCN3CCCCC3)cc2)c1-c1ccccc1 +c1ccc2c(CCNc3ccc(CN4CCOCC4)cc3)c[nH]c2c1 +Cc1cccc(NC(=O)Nc2ccc(S(=O)(=O)Nc3ccc(CC(C)(C)N)cc3)cc2)c1 +Cc1nnn(-c2ccc(-c3ccc(C4(C(=O)NS(C)(=O)=O)CC4)cc3)cc2)c1NC(=O)OC(C)c1ccccc1 +CC1CN(C(C)CO)C(=O)c2cc(NC(=O)NC3CCCCC3)ccc2OC1CN(C)S(=O)(=O)c1ccc(Cl)cc1 +Cc1cccc(-c2nn(CC(=O)Nc3cccc(C(N)=O)c3)cc2-c2ccc3ncccc3c2)n1 +COc1ccc2[nH]cc(CCNCCCc3ccccc3)c2c1 +COc1ccc(CN=C2NC(CO)C(O)C(O)C2O)cc1 +Cc1ccc(NC(=O)c2cccc(C(C)(C)C#N)c2)cc1Nc1ncnc2cnc(N(C)C3CCN(C)CC3)nc12 +CCC1(c2ccc(C)cc2)Oc2ccccc2-n2cccc2C1=O +Cc1cnc2c(C(=O)NC3C4CC5CC3CC(C#N)(C5)C4)cnn2c1 +COc1cc(Oc2ccc3c(N)c(OC)ccc3n2)cc(OC)c1OC +CCN(CC)CCOc1ccc2c(c1)C(C)(C)c1oc3cc(O)ccc3c1C2=O +CCNC(=O)Nc1ncnc2c1ncn2C1OC(CC(=O)O)C2OC(C=Cc3ccccc3)OC21 +O=C(c1ccc(-c2ccc3c(c2)CCN(CCN2CCCC2)C3=O)c(F)c1)N1CCCC1 +Cn1c(-c2cnc(NC(=O)c3cccc(C#N)c3)s2)nc2ccccc21 +CCOC(=O)CNC(=O)C(=O)C(COCc1ccccc1)NC(=O)C(CC1CCCCC1)NC(=O)c1cc(SC)ccc1Cl +CNC(=O)c1cc(Oc2ccc3c(c2)CC(C(=O)Nc2ccc(CN)c(C(F)(F)F)c2)CC3)ccn1 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+O=C1N(Cc2ccc(Br)cc2)C(Cc2ccccc2)C(O)C(O)C(Cc2ccccc2)N1Cc1ccc(Br)cc1 +O=[N+]([O-])c1cn2c(n1)OCC(OCc1cccc(-c3ccc(F)cc3)n1)C2 +O=c1[nH]c(-c2ccc(S(=O)(=O)N(CCC3CC3)c3sc4ccccc4c3Cl)cc2)no1 +CC1(C)CC(=O)C2=C(C1)Nc1c(O)cccc1N(C(=O)c1cccnc1)C2c1ccc(OCc2ccccc2)cc1F +COc1c(C)cnc(Cn2cc(CCCO)c3c(Cl)nc(N)nc32)c1C +O=C(Nc1ccc(-n2cncn2)cc1)NC1CCCCC1CN1CCCC(Cc2ccc(F)cc2)C1 +CCc1[nH]c2nc(Sc3ccc4nccnc4c3)nc(N3CC4C(N)C4C3)c2c1Cl +CCS(=O)(=O)n1c2c(c3cc(C(=O)N4CCC(C)CC4)ccc31)CN(C(C)C)C2 +CCCON1C(=O)C(NC(=O)OCCCCC2CCCCC2)C1C +COc1cccc(NC(=O)N2CCNCC2COc2cccnc2)c1 +CC#CCOc1ccc(S(=O)(=O)N2CC(CC(=O)O)SC(C)(C)C2C(=O)NO)cc1 +Cc1nn(C2CCCCC2)c2sc(C(=O)NCCN3CC(=O)NC3=O)cc12 +NC(=O)n1cc(NC(=O)N2CC(N)CC2C(=O)NCc2cccc(Br)c2)c2ccccc21 +COc1cc(N2CCN(C)CC2)c2[nH]c(C(=O)Nc3ccc(N4CCOCC4)cc3)cc(=O)c2c1 +COc1cc(F)c(-n2c(=O)[nH]c3csc(C(=O)O)c3c2=O)cc1CN(C)c1c(F)cccc1F +CC(=O)Nc1ccc(S(=O)(=O)NNc2cc(Cl)cc(Cl)c2)cc1 +COc1cc(-c2cnn(C)c2CO)ccc1Nc1ncc2ccnc(NCC3(C)CCOC3)c2n1 +CNc1ccc(C(=O)NCCCCCC(=O)Nc2ccccc2N)cc1 +O=P(O)(O)C(CCCc1cccc(Oc2ccc(Cl)c(Cl)c2)c1)S(=O)(=O)O +CN(CCO)CCc1cc(C(=O)NCC23CC4CC(CC(C4)C2)C3)c(Cl)cn1 +CN(C(=O)Cc1ccccc1)C(Cc1ccc2ccccc2c1)NC(=O)C1CCCCC1NC(=O)c1c[nH]c2ccccc12 +O=C(NC1CCC(N2CCOCC2)CC1)c1cc2cc(Nc3nccc(-c4ccccn4)n3)ccc2[nH]1 +COc1cc2ccccc2cc1C=NNC(=O)c1cc(O)c(O)c(O)c1 +CC1CN(CCCCN2C(=O)CC3(CCCC3)CC2=O)CCN1c1nsc2ccccc12 +O=C(CC1NCCCC1O)Cn1cnc2cc(Br)c(Cl)cc2c1=O +O=C(O)CN1CN(Cc2ccc(C(F)(F)F)cc2)S(=O)(=O)c2cc(Br)cnc21 +O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)N1CCCCC1 +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1C(=O)NC1CCOCC1 +COc1ccc(CC(=O)NCC2CCCN(Cc3cc(OC)cc(OC)c3)C2)cc1 +CN1CCC(n2cc(Cn3cc(NC(=O)c4cnn5cccnc45)c(-c4cc(Cl)ccc4OC(F)F)n3)nn2)CC1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccc(-c3nnco3)cc2)c1C +CON=C1CC(C)(C)Nc2cc(F)c(-c3cccc4cc[nH]c34)c(F)c21 +O=C(NC1CC1)c1ccc(-c2cnn3c(NCCN4CCOCC4)nc(Oc4ccccc4)nc23)cc1 +CN1CCN(c2nc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)ns2)CC1 +CC1=CCC2C(C1)c1c(O)cc(CC#CCCO)cc1OC2(C)C +O=C(Nc1ccc(-c2ccc(C(=O)C3CCCC3C(=O)O)cc2)cc1)Nc1ccc(C(F)(F)F)cc1 +NC(=O)c1cccc2c(NCc3ccc(C(F)(F)F)cc3)ncnc12 +Cc1nc2cc(-n3ncc(C(=O)c4cc5cc(C(F)(F)F)ccc5[nH]4)c3N)ccc2[nH]1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4)nc(NC(C)c4cccnc4)n3)cccc2s1 +CCCCCCNc1nccc(-c2c(-c3ccc(F)cc3)nc3cc(CN(C)C)ccn23)n1 +Cc1cc(=O)c2c(O)cc(O)c(C3CCN(C)CC3O)c2o1 +COC1CCC2(CC1)Cc1ccc(CCC3CC3)cc1C21N=C(N)N(Cc2ccc(S(C)(=O)=O)cc2)C1=O +CCB(CC)OC(=O)C(N)CCCCNC(=S)NCCc1ccc(S(N)(=O)=O)cc1 +NS(=O)(=O)c1c(F)c(F)c(-n2cc(CCCCCl)nn2)c(F)c1F +COc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2)c1 +CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(=O)Nc1cccc(S(=O)(=O)C(F)(F)F)c1 +CC(C)CN1CCC([S+]([O-])c2ccc(CNC(=O)c3cc4ccncc4o3)nc2)CC1 +Cc1c(N(Cc2ccccc2)S(=O)(=O)c2ccc(F)c(F)c2)sc2ccccc12 +O=C(O)c1ccc2c(c1)nc(NCc1ccccc1)c1ccncc12 +COc1ccc(N2CCN(CCCNC(=O)Cn3c(=O)c4cccn4c4cccnc43)CC2)c(OC)c1 +CCNCCNc1cc(-c2cccc(C(F)(F)F)c2)c(C#N)c2nc3ccccc3n12 +Cc1ccc(C2CC2COc2nc(C)ncc2-c2nn(C)c(=O)cc2C)nc1 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+O=S(=O)(NCC1CCC(Nc2nc3c(s2)CCSc2ccccc2-3)CC1)c1cccc2ccccc12 +CCc1cc2c(cc1N1CCC(O)(C3CC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CC(C)Nc1nc(-c2ccc(C(C)(C)C#N)cc2)cc2ncn(C)c(=O)c12 +CCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1-c1nc2cc(OC)cc(OC)c2c(=O)[nH]1 +CCC(C)Nc1cc(C(=O)NC2CC3CCC(C2)N3c2ccc(C(=O)C3CC3)cn2)c(C)cc1C(N)=O +O=C(Nc1ccc(F)c(-c2nc3cc(-c4ccccc4Cl)cnc3[nH]2)c1)N1CCCC1 +Cn1ccc2nc(COc3ccc(-c4ccc(=O)[nH]c4-c4ccc(Cl)cc4)cc3)ccc21 +Cc1ccc(C(=CCNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)c2ccc(C)cc2)cc1 +CC1NC(=O)c2cc(-c3c(F)ccc4c(=O)n(C)c(NC(C)(C)C)nc34)[nH]c21 +CCOC(=O)c1cnc(N(C)N2C(=O)C=C(C)C2=O)nc1C(F)(F)F +Cc1ccc(NC(=O)c2cccc(N3CCOCC3)c2)cc1NC(=O)c1ccc(OCc2cccnc2)cc1 +O=C(O)CCNC(=O)c1ccc(-c2cc(C(F)(F)F)ccc2CNc2ccc(-c3ccc(Cl)cc3F)cc2)cn1 +O=C(Nc1ccccc1F)c1ccc(Nc2nc(Nc3ccc(O)cc3)ncc2F)cc1 +COc1ccc(-c2c(-c3cc(OC)c(OC)c(OC)c3)ncn2C)cc1N +CCc1cccc(NC(=O)N2CCc3nc(-c4c(C)noc4C)nc(-c4ccccc4C)c3C2)c1 +COc1ccc(S(=O)(=O)NCC2(c3cccc4ccccc34)CC2)cc1N1CCN(C)CC1 +C#CC1(O)CCC2C3CCC4CC(F)(F)CCC4(C)C3CCC21C 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+COc1ccccc1N1CCN(CCCc2cn(-c3ccc(N(C)C)cc3)nn2)CC1 +Cc1cc(Nc2ccccc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +Cn1cc2c(nc(NC(=O)NC3CCN(Cc4ccccc4)CC3)n3nc(-c4ccco4)nc23)n1 +Fc1cnccc1-c1cc(-c2ccc(F)c(-c3ncccc3F)c2)cnn1 +CC(C)CC(NC(=O)C1(c2ccccc2)CC1CN1CCC2(C)c3cc(O)ccc3CC1C2C)C(=O)NCCCCCCN +O=C(NCc1ccc(Cl)cc1Cl)Nc1cccc2ccc(O)cc12 +O=C(NC1CC1)C1OC(n2cnc3c(NCCc4cn(CCN5CCCCC5)c5ccccc45)ncnc32)C(O)C1O +O=C(CCCn1c(=S)[nH]c2ccccc2c1=O)N1CCC(c2ccccc2)CC1 +COc1cc(C2=NCC(=O)N3CCc4c(I)cccc4C3=C2)ccn1 +CC1CN(Cc2ccc(C(C)Nc3ncc(F)c(N4C(=O)OCC4C(C)C)n3)cc2)CC(C)O1 +Fc1ccc(OCCCN2CCN(c3ncc(F)cn3)CC2)cc1 +Cc1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 +CC(=O)Nc1nc2ccc(-c3nn(Cc4cc5cccc(C)c5c(=O)n4C4CC4)c4ncnc(N)c34)cc2s1 +CNCc1cc(C(=O)N2CCN(C3CC3)CC2)ccc1Oc1ccccc1 +Nc1ncc(-c2cc(C3CC4CCC(C3)N4CC(F)(F)F)nc(N3CC4CC3C4)n2)cn1 +COc1ccc(C2N(c3ccnc(NC(C)c4ccccc4)n3)C(=O)OC2(C)C)cc1 +CC(C)(C)c1ccc(O)c(C(=O)Nc2ccc(CN)cc2)c1 +COc1ccc(C(=O)N2CCC(N3CC(CC#N)(n4cc(-c5ncnc6[nH]ccc56)cn4)C3)CC2)cc1C#N 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+O=c1c2c(oc(O)c1C(c1ccccc1)C1CC1)CCCCCCC2 +COc1ccc(S(=O)(=O)N2CCN(C(S)=NCc3ccccc3)CC2C(=O)NO)cc1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2C)cc1-c1ccc2nc(NCCN3CCCCC3)ncc2c1 +COc1ccc(COC2CC3C(C2C)C2OC(=O)C(C)C24C=CC3(C)OO4)cc1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)c(-c3ccccc3)cc21 +CCCCCCCCC=CCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCc2cccnc2)cc1 +O=C(Nc1cc2ccc(-c3ccc[nH]3)cc2cn1)C1CC1 +O=C(O)c1ccc(-c2ccc3c(c2)CC(NCC(O)c2cccc(Cl)c2)CC3)cc1 +CN1CCC(=O)N=C1NC(=O)Nc1cccc(C#N)c1 +Cc1cc(NC(=O)Nc2ccc(F)c(F)c2)n(CC(F)(F)F)n1 +O=C(COc1cccc2c1CCCN2Cc1ccccc1)NCC(O)CN1CCc2ccccc2C1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ncc3cc(Cl)cnc32)cc1Nc1cnn(CCCF)c1 +O=C(Nc1ccccc1)c1ccc(OCCCN2CCCC2)cc1OCc1ccccc1 +O=S(=O)(c1ccccc1)N1CCC2=Cc3c(cnn3-c3ccc(F)cc3)CC2(CN2CCCCC2)C1 +CCCN(CCC)C1CCc2c(ccc(C(O)Cc3ccc(Cl)c(Cl)c3)c2OC)C1 +CC(C)N(CCOc1ccc(-c2oc3nccc(NCCN4CCNCC4)c3c2-c2ccccc2)cc1)C(C)C +CCN(CC)c1ccc2cc(NC(=O)CCc3ccc(C(F)(F)F)cc3)ccc2n1 +CC(Oc1ccccc1)C(=O)N(Cc1ccc(Cl)cc1)CC1CCCN1 +Nc1ncnn2ccc(C(=O)Nc3cccc(CNC(=O)Nc4cccc(F)c4)c3)c12 +CCC(CNC(=O)NCCCCNC(=O)NCC(CC)C12CC3CC(CC(C3)C1)C2)C12CC3CC(CC(C3)C1)C2 +CC(=O)c1c(C)c2cnc(Nc3ccc(N4CCC(N)C4)cn3)nc2n(C2CCCC2)c1=O +N#CC1CC(NCC(F)(F)F)CCC1n1cc(C(N)=O)c(Nc2ccnc(F)c2)n1 +CCCCCCCCCCCCCCCCCCCCOC1CC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)CO1 +O=Nc1c(-c2c(O)[nH]c3ccc([N+](=O)[O-])cc23)[nH]c2ccccc12 +CCS(=O)(=O)Nc1cc(F)cc(CNc2ccc(Cc3c[nH]c4ncc(C)cc34)c(F)n2)c1 +O=C(Nc1c(O)cccc1-c1nc2c(C(=O)O)cccc2o1)c1cc(-c2ccccc2)on1 +O=C(C1CCCNC1)N1CCN(c2nccc(NCc3ccc(Cl)cc3Cl)n2)CC1 +CCC(NC(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2ccc(N)nc2)c1F +CN(C)Cc1cc(CNS(C)(=O)=O)ccc1Oc1ccc(OC(F)(F)F)cc1 +CC(C)(C)c1nc(C2CC2)cc(N2CCN(CCCCNC(=O)c3cn4ccccc4n3)CC2)n1 +OCC1OC(c2ccc(Cl)c(Cc3nnc(-c4cccs4)s3)c2)C(O)C(O)C1O +N#Cc1nc(CCCN2CCC(O)CC2)cc(-c2cccc(C(F)(F)F)c2)n1 +Cc1cccc(Nc2cc(CN(Cc3ccccc3C(F)(F)F)CC3CCCCC3)nn2C)c1C +COc1cc(-c2nc(-c3ccnc(C)c3)c3n2CC(C)OCC3)ccc1OC(F)(F)F +CC1=CCC2C(C1)c1c(O)cc(C(C)(C)c3cccc(C#N)c3)cc1OC2(C)C +Nc1nc(O)c2c(n1)NCC(CCNc1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1)N2 +CS(=O)(=O)c1ccc(-c2ccc(CNC(=O)c3ccc(OCCC(F)(F)F)nc3)cc2)cc1 +CCOc1cnc(N2CCN(c3noc(C(C)(F)F)n3)C(C)C2)c(C)c1 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1(C)CCN(C(=O)C(F)(F)CN)C1)CC2 +NC1CN(c2ccc3nc(=O)ccn3n2)CCC1c1cc(F)c(F)cc1F +Cc1cc(-c2nc3cc(Cl)cnc3n2Cc2ccccc2)cn(C)c1=O +COCCCC(CC(=O)O)N1CCc2cc(OCc3ccc(C(=N)N)cc3)ccc2C1=O +O=C(C#CCO)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +Fc1ccc(F)c(OC(c2ccccc2)C2CCNC2)c1Cl +CCCCNc1nc(NCc2csc(-c3cccs3)n2)nc(N2CCCC2CNS(=O)(=O)c2cccc(Cl)c2)n1 +CCN1CCN(C2CCC(NC(=O)c3cc4c(C)nn(C5CCOCC5)c4s3)CC2)CC1=O +Cc1ccc(C2C3=C(CCCC3=O)NC3=C2S(=O)(=O)CC3)cc1I +O=C(CCc1ccc(-c2ccc(O)cc2Cl)s1)Nc1ccccc1C(=O)O +CONC(=O)c1cnn2ccc(N3CCCC3c3cc(F)cnc3CO)nc12 +Cn1c(CNc2ccc(C(=N)N)cc2F)nc2cc(C(=O)N(CCC(=O)O)c3ccc(F)c(Cl)c3)ccc21 +CCc1nccc(-c2ccc(C(=O)NCCOC)c(F)c2)c1C#Cc1ccc(N)nc1 +Cc1ccc(-n2ncccc2=O)cc1NC(=O)C1=CN(C)C(=O)CC1c1ccc(F)cc1 +CCc1ccc(Cc2sc(C3OC(CO)C(O)C(O)C3O)nc2Br)cc1 +CNc1ccc(-c2ccc(C(=O)NC(CO)CC(C)C)cc2C(=O)O)c(C(=O)Nc2cccc(C(N)=O)c2)c1 +COc1ccc2c(c1)C(CNC(C)=O)Cc1ccccc1C2 +Cn1nc(C(F)(F)F)cc1-c1ccc(Oc2cc(F)c(S(=O)(=O)Nc3nccs3)cc2Cl)c(C#N)c1 +CC(=O)OCCCCC(C1=C(C)C(=O)C(C)=C(C)C1=O)c1cccnc1 +O=C(CCCCO)CCCCCCCC(O)C1NC(CO)C(O)C1O +COC(=O)c1ccc(Cc2n[nH]c(=O)c3c2CCCC3)cn1 +CN(C)CCNc1nccn2c(-c3ccncc3)c(-c3ccccc3)nc12 +Cc1cc(Cl)ccc1-c1cccc(COc2ccc(C(CC(=O)O)c3nnnn3C)cc2)c1 +CCOC(=O)Nc1ccc2cc3ccc4c(c3nc2c1)COCN4 +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2Cc2cccc([N+](=O)[O-])c2)cc1 +COc1ccc2c(c1)c(CCN(O)C(N)=O)c(C)n2C(=O)c1ccc(Cl)cc1 +Cc1c(N(Cc2ccc(OCC3CCCC3)cc2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +NC(=O)C12CC3CC(C1)C(NC(=O)c1cccc(NS(=O)(=O)c4cc(Cl)cc(Cl)c4)c1)C(C3)C2 +CSCC(NC(=O)C(Cc1ccccc1)OC(=O)N1CCC(N)CC1)C(=O)NC(CC1CCCCC1)C(O)CCSc1nccs1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)C(C)(C)C(=NNC(N)=O)CC2 +CCC(O)=C(C#N)C(=O)Nc1ccc(OS(=O)(=O)C(F)(F)F)cc1 +CNCC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +O=C(Cc1ccccn1)Nc1ccc(CCCCc2nnc(NC(=O)Cc3ccccc3)s2)nn1 +Cn1c(=O)c2c(nc3n2CCCN3CCc2cccc(Cl)c2)n(C)c1=O +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CC(S(C)(=O)=O)C4)ncn3)c2c1 +O=C1CC(N2CCN(CCCOc3ccc(C(=O)C4CC4)cc3)CC2)N1 +CC(=O)N1CCN(C(=O)c2cc(Sc3cnc(Nc4cc(C)cc(C)n4)s3)ccc2O)CC1 +Cc1sc2c(c1C)C(c1ccc(Cl)cc1)=NC(CC(=O)Nc1ccc(N)cc1)c1nnc(C)n1-2 +Cc1nn(C(=O)c2[nH]nc(-c3ccc(Cl)cc3)c2N)c(C)c1Cl +O=C1Nc2ccc(S(=O)(=O)N3CCCC3COc3ccncc3)cc2C1=O +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc(F)cc3)NC(=O)NC1=O)C2 +CC(C)(O)C#Cc1cc2c(cc1F)OCCn1cc(C(N)=O)nc1-2 +CC1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)COCCC(N)=N1 +CN(CCCc1ccccc1)CCN(C)CCOC(c1ccc(F)cc1)c1ccc(F)cc1 +O=C1C(=CC=Cc2ccccc2)c2ccccc2N1Cc1ccccc1 +CCS(=O)(=O)c1ccc(S(=O)(=O)NC)cc1Nc1cc(Nc2ccc(Cl)cn2)ncn1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1 +CC(CN1CCC2(CC1)C(=O)NCN2c1ccccc1)NC(=O)c1ccc(F)c(F)c1 +COc1cccc2c1OC1(CCN(C)CC1)N1N=C(c3ccc(F)cc3)CC21 +COc1ccc(-c2[nH]c3ccc(C(C)C)cc3c2C=C(C#N)C#N)cc1 +CN(CCCN1c2ccccc2Oc2ccccc21)CCc1ccccc1 +CCCCN(CC)c1cc(C)nc2c(-c3ccc(OC)cc3OC)c(C)nn12 +CCCCCCCCC=CCCCCCCCC(=O)OCCCOP(=O)(O)OCC(N)C(=O)O +Cn1cc(C(=O)O)c2ccc(N3CCC(OCc4c(-c5c(Cl)cccc5Cl)noc4C4CC4)CC3)cc21 +NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1cccnc1-n1ccc(C2CC2)n1 +CCCC1Oc2ccc(-c3cncnc3)cc2C2(COC(N)=N2)C12COC2 +O=C(Nc1ccc(C(=O)N2CCN(c3cnccn3)CC2)cc1)N1Cc2ccc(C(F)(F)F)cc2C1 +CN1CCC(OC(c2ccc(F)cc2)c2ccc(F)cc2)CC1 +CCOC(=O)C1(c2ccccc2)N=C(c2ccc(OC)cc2)N(Cc2ccccc2)C1c1ccc(NCC2CCCCC2)cc1 +Cc1cc(C)c(-n2nnnc2SCC(=O)Nc2ccccc2Cl)c(C)c1 +CC(C)CN1CCC(n2nnnc2CCCOc2ccc3[nH]c4nc(O)nc-4cc3c2)CC1 +CCCCN1CCN(c2nc3c(S(=O)(=O)c4cccc5ccccc45)cccc3o2)CC1 +CS(=O)(=O)N1CC=Cc2cccc(c2)Nc2ncc(C(F)(F)F)c(n2)NCc2cccnc21 +[C-]#[N+]C1(C)CCC2C(C)CC3C=C(C)C(C)C4CCC1C2C34 +COCOC(C)(C)c1ccc(-c2ccnc(NCc3ccc(C(=O)Nc4ccccc4N)cc3)n2)cn1 +Cc1cc(C)nc(-n2nc(C)cc2Nc2ccccc2)n1 +CN1CCC2(c3cccc(O)c3)CC(=O)C(=Cc3cccc(Cl)c3)C1C2 +CCCc1cc2c(OC)noc2c(CCC)c1OC(C)(C)C(=O)O +COc1cc2c(c3c1c(=O)c1cc4ccccc4cc1n3C)C(O)C(OC(=O)C=Cc1ccc(Br)cc1)C(C)(C)O2 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+CC(=O)Nc1nc2ccc(-c3nn(Cc4cc5cccc(F)c5c(=O)n4C(C)C)c4ncnc(N)c34)cc2s1 +CCCC(=O)NCc1nc(-c2ccc3[nH]c4c5c(c6c(c4c3c2)C(=O)NC6=O)CCC5)cs1 +Cn1c2ccc(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +COc1ccc(OC)c(-c2cccn(C(CN3CCC(O)C3)c3ccccc3)c2=O)c1 +Cc1ccc(OCc2nc(-c3ccccc3)no2)c(C)c1 +COc1cccc(-c2cccc(C3(C)N=C(N)CCS3)c2)c1 +COc1cc(N2CCN(S(C)(=O)=O)CC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +Cc1cc2ccccc2nc1-c1ccc(N(Cc2ccc(F)cc2)C(=O)c2ccc(O)cc2O)cc1 +CC(C)C(=O)N(c1ccc([N+](=O)[O-])cc1)C1CCC2C3CCC4N(C)C(=O)CCC4(C)C3CCC21C +N=C(N)Nc1ccc(NC(=O)c2cc3cc4ccccc4cc3c(Br)c2O)cn1 +COc1cc(-c2cn(CC(=O)N(Cc3ccccc3)C(C)c3ccccc3)nn2)ccc1-n1cnc(C)c1 +CC(=O)c1ccc(N2CCN(C(=O)c3cccc(Cl)c3)CC2)s1 +COc1cccc2c1CCN(Cc1ccc(C(C)NC(=O)c3cncs3)cc1)C2 +Cn1c(C#N)ccc1-c1ccc2c(c1)CCCC2(O)c1ccccc1 +Cc1c(COC(=O)NC(=N)N)cccc1-c1cnc(N2CCOCC2)nc1 +COc1cccc(-c2n[nH]c(Cc3ccc(Cl)c(Cl)c3)n2)c1OC +Cc1cc(C)c(S(=O)(=O)NC(=N)N2CC(c3ccccc3)C(c3ccc(Cl)cc3)=N2)c(C)c1 +Oc1ccccc1CNCCCCCCCCCNc1c2c(nc3ccccc13)CCCC2 +Cc1ccccc1-c1cn(C2OCC(O)C2O)c2ncnc(Nc3ccc4c(c3)OCCO4)c12 +O=C(O)CC(NC(=O)CNC(=O)c1cc(O)cc(NC2=NCC(O)CN2)c1)c1cc(Cl)cc(I)c1O +CC(C)N1CCC(Oc2ccc3c(c2)CCN(C2CCN(C4CCC4)CC2)C3=O)CC1 +CCCCCCCCCNC(=O)Cc1c(C)n(C(=O)c2ccc(Cl)cc2)c2ccc(OC)cc12 +OC1CCN(CCOc2ccc(Oc3nc4ccccc4s3)cc2)CC1 +c1ccc2c(NCCCCCCN3CCCCC3)c3c(nc2c1)CCCC3 +C=CCCN1CCN(C(=O)c2ccc(NCc3ccc(-c4cccc(F)c4C(=O)OC)cc3F)nc2)CC1 +Cc1c(-c2ccnc(N)n2)sc2ccc(C(N)c3cccc(Cl)c3)cc12 +COc1cc(C=CC(=O)NCCn2c(C)cc3ccccc32)cc(OC)c1 +COc1ccc(-c2[nH]c(-c3ccccc3)nc2CCNS(=O)(=O)N2CCN(c3ccccc3)CC2)cc1 +COc1cccc(C2(N3CCN(c4ccccc4)CC3)C3CC(C)CC32)c1 +COc1ccc(Nc2ncc(C(N3CCN(S(C)(=O)=O)CC3)C(F)(F)F)cc2-c2nc(C)nc(N)n2)cn1 +Cc1cc(N2CCC(C)CC2)nc2ccc(NC(=O)C3CCC(C)CC3)cc12 +CS(=O)(=O)c1ccc(-c2ccc3c(-n4ccnc4)c(C#N)cnc3c2)cc1 +N#Cc1c(N)nc(SCc2csc(-c3ccc(Cl)cc3)n2)nc1-c1ccc(OC(F)(F)F)cc1 +CN(Cc1cccc2ccccc12)C(=O)C(O)C(N)CC1CCCCC1 +O=S(=O)(c1ccc(Cl)cc1)N1Cc2c[nH]nc2CC1c1ccccc1 +CCCC(=O)c1cnc2ccc(-c3cc(Cl)c(O)c(OC)c3)cc2c1Nc1ccc(N2CCNCC2)nc1 +O=C(O)c1ccc(N2C(=O)C3ON(c4ccccc4)C(c4ccc([N+](=O)[O-])cc4)C3C2=O)cc1 +Cc1nnc(C)n1-c1ccc(OCCCN2CCCCC2)cc1 +Cn1c(=O)cc2c3c(c(N)ccc31)C(=O)c1ccccc1-2 +CC(CO)n1c2cnccc2c2cnc(Nc3ccc(N4CCC(O)C4)nn3)nc21 +O=C(Cc1cccc(NCC(F)(F)c2ccccn2)[n+]1[O-])NCc1cc(Cl)ccc1-n1cnnn1 +CCC(NC(=O)C1CC(Sc2ccccc2)CN1C(C)=O)C(=O)c1nc2ccccc2o1 +CC(C)(O)COc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +COc1cc(Nc2nc(N)nc(-c3ccccc3)n2)ccc1-c1cnco1 +CCOc1cc(N2CCOCC2)ccc1Nc1nc(NC2CCCCC2)c2nc[nH]c2n1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OCc2ccc(-c3ccccc3)cc2)C1c1cccc([N+](=O)[O-])c1 +COc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(OC)cc2)cc1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1cc(Cl)ccc1-n1cnnn1 +CC(C)(C)NC(=O)Nc1cnn2ccc(N3CCCC3c3cc(F)ccc3F)nc12 +Cc1cc(C)cc(CC(=O)N(C)CC(c2cccc3c2OCO3)N2CCC(N3CCCCC3)CC2)c1 +O=C(C1CCS(=O)(=O)CC1)N1CCN(c2ncc(F)cn2)CC1c1cccc(F)c1 +COc1cc(OCc2csc(CN(C)C)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Nc1ncc2c(n1)-c1ccccc1C(c1ccccc1)=NC2 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(C#N)c2NCc2cccs2)nc1 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+O=Cc1cccc(CN2C(=O)N(Cc3cccc(C=O)c3)C(Cc3ccccc3)C(O)C(O)C2Cc2ccccc2)c1 +Cc1cc(Nc2cc(N3CCN(C)CC3)nc(NCc3cc(-c4ccccc4)no3)n2)[nH]n1 +CCCN(CCC)c1cc(C)nc2c(-c3ncc(C)cc3NC)c(C)nn12 +CC(=O)NC(C)c1ccc(OC2CCN(c3ncnc(N(C)C)c3F)C2)cc1 +O=[N+]([O-])c1ccc2[nH]c3cnc([N+](=O)[O-])cc3c2c1 +Nc1cc(Oc2ccccc2-c2ccc(-c3cnc(N)nc3)c(F)c2)ccn1 +CC(Nc1nc(N)nc(N)c1C#N)c1nc2cccc(Cl)c2c(=O)n1-c1cccc(Cl)c1 +Cc1cn2ccc(N3CCC(OC(=O)N4CCN(C(C)C)CC4)CC3)cc2n1 +O=C1c2ccccc2S(=O)(=O)N1CCCCN1CCC(c2ccccc2)C1 +CC1(C)CC2CC(C)(CN2C(=O)c2cc(Cl)c(-c3csc4ccccc34)cc2Cl)C1 +CCc1nnc2ccc(-c3n[nH]c4ccc(C(=O)NC5CCCN(Cc6c(F)cccc6OC)C5)cc34)cn12 +COc1cc(C=CC(=O)NCCCNc2c3c(nc4ccccc24)CCCC3)ccc1OCCCCO[N+](=O)[O-] +CN(C)C(=O)C1CCN(c2ccnc3c2c(C=C2Oc4cccc(O)c4C2=O)cn3C)CC1 +Clc1cccc(N2CCN(Cc3nc4ccccc4[nH]3)CC2)c1 +NC1CC(O)CN(c2ccncc2NC(=O)c2csc(-c3c(F)cccc3F)n2)C1 +O=C(O)CNC(=O)c1c(=O)oc(O)c2ccc(-c3ccc(OC(F)(F)F)cc3)cc12 +O=C1NCc2c1c1c(c3c2c2cc(CO)ccc2n3CCCO)Cc2ccccc2-1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCN(c3ccc([N+](=O)[O-])cc3)CC2)cc1 +COc1ccc(C2C(c3ccccc3)C(=S)N2c2cc(OC)c(OC)c(OC)c2)cc1 +COc1cc(OC)c(-c2cc3ccccc3o2)cc1C=CC(=O)c1ccc(C(=O)O)cc1 +CCCC1SC(=Cc2nc3ccc(F)cc3[nH]2)NC1=O +CC1=NNC(=O)CC1c1ccc(OC2CCN(C3CCC3)CC2)cc1 +Cc1ccc(C(=O)NC(=S)NNC(=O)COc2ccccc2C)cc1 +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2ccc(OC3Cc4ccccc4C3)c(C(=O)O)c2)c1 +Cc1cc(=O)oc2cc(NC(=O)NS(=O)(=O)c3ccccc3Cl)ccc12 +Cc1ccoc1C(=O)Nc1cccc(Oc2ccnc3cc(C(=O)NCCO)sc23)c1 +COCc1nc2c(C(=O)NCc3ccccc3)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +O=C(NNc1ncnc2sc3ccccc3c12)c1ccccn1 +CC(C)(CCO)NC(=O)c1cc(NC(=O)c2cc(-c3ncccc3F)ccc2Cl)n(-c2ccccc2)n1 +CCCCn1c(Sc2cc(OC)c(OC)c(OC)c2Cl)nc2c(N)ncnc21 +O=S(=O)(Nc1nccs1)c1cc(Cl)c(NCC23CCCC2(O)CCC3)cc1F +FC(F)(F)c1cc(CNCc2cnccc2-c2ccccc2)cc(C(F)(F)F)c1 +Cc1c[nH]c2cccc(OCC(O)CN3CCN(C(c4ccccc4)c4ccccc4)CC3)c12 +O=C(Cc1ccccc1)Nc1nnc(CCSCc2nnc(NC(=O)Cc3ccccn3)s2)s1 +CNC(=O)c1ccc(Nc2nc(OC3CCCC3)c3c(-c4ccncc4)c[nH]c3n2)c(OC)c1 +Cc1c(Br)cc(-c2cc(Cl)ccc2OCc2ccccc2)n1-c1cccc(C(=O)O)c1 +O=C(Cc1ccccc1)NC(Cc1ccc2ccccc2c1)NC(=O)C1CCCCC1NC(=O)c1c[nH]c2ccccc12 +Cc1cc(C)cc(NC(=O)Nc2ccc(NS(N)(=O)=O)cc2)c1 +CCCCC(C)C1CC(=O)NC(Cc2ccccc2)C(=O)NC(CO)C(=O)NC(Cc2ccccc2)C(=O)O1 +COc1ccc(-n2nnnc2N)cc1CNC1CCCNC1c1ccccc1 +O=C(C=Cc1ccc2c(c1)cc(C(=O)c1ccccc1)n2S(=O)(=O)c1ccccc1)NO +COc1cc2nc(N3CCN(C(=O)C4COc5ccccc5O4)C(C)C3)nc(N)c2cc1OC +COC(=O)C1CC(O)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +NS(=O)(=O)Oc1ccc(NC(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 +Cc1ccc(N2CCc3ncnc(NC(CO)c4ccc(C(F)(F)F)nc4)c3C2)c(C#N)c1 +CC(C)(C)NC(=O)C1CCN(Cc2cc(NC(=O)c3cccc(C(F)(F)F)n3)ncn2)CC1 +COc1cc2ncnc(Oc3ccc(NC(=O)NC4(C#N)CCCC4)c4ccccc34)c2cc1OC +Cc1cccc(C(=O)Nc2cccc(CNc3ncnc4c(C(N)=O)cccc34)c2)c1 +CC(CC(=O)O)Cc1nc(CCCc2ccc3c(n2)NCCC3)no1 +CN1CCC(NC(=O)c2cc(-c3c(O)cc(O)cc3Oc3ccc(N4CCCC4)cc3)on2)CC1 +COc1cc(C2=NC(c3ccc(Cl)cc3F)C(C(=O)Nc3cc4cn[nH]c4cc3F)=C(C)N2)ccn1 +CCN(CCCCCCn1c(=O)c(=O)n(CCCCCCN(CC)Cc2ccccc2OC)c2ccccc21)Cc1ccccc1OC +COc1ccc(-c2cc(C(N)=O)nc3cc(C(O)Cc4ccc(Cl)nc4)ccc23)cc1 +Nc1cc(C(=O)N2CCCC2)cc2nc(-c3cccs3)nn12 +O=c1ccc2cc(N3CCN(CCCCc4c[nH]c5ccc(F)cc45)CC3)ccc2o1 +CCN(CC)c1nc2ccccc2n2nc(-c3ccco3)nc12 +CCCCN1CCC(COC(=O)c2ccc(N)c3c2OCCO3)CC1 +Cc1nnc2c(NC3CCN(S(=O)(=O)C4CCNCC4)CC3)cc(N(C)Cc3ccccc3)nn12 +CCN(CC)CCNC(=O)c1cccc2nc3ccc4c(OC)cccc4c3nc12 +CCc1ccc(C(=O)C[n+]2cc(-c3ccc(C)cc3)n3c2CCC3)cc1 +O=C(NCCCNCCNC(=O)OCc1ccccc1)OCc1ccccc1 +Cc1cc(Cl)ccc1NC(=S)NNC(=O)C(O)(c1ccccc1)c1ccccc1 +CCN(CC)C(CNC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1)C(=O)NO +C#Cc1cccc(Nc2ncnc3cc(OC)c(OCCCCCCn4ccnc4[N+](=O)[O-])cc23)c1 +Cc1ccc(C(=O)Nc2cccc(Br)c2)cc1C#Cc1cnc2ccnn2c1 +O=C(N1CCC(F)CC1)N1CCc2nc(C#Cc3ccccc3)sc2C1 +Cc1ccc2c(c1)c1c(n2CCc2ccncc2)CCN(C)C1 +CCOCCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +Cc1cc(O)cc(C)c1CC(N)C(=O)N(Cc1ccccc1)C(C)c1nc(-c2ccccc2)c[nH]1 +CC1(C)OC(c2ccnc(NCCC#N)n2)=C(c2cc(Cl)cc(NS(=O)(=O)c3c(F)cccc3F)c2F)C1=O +CN1CCN(C)C(c2c(-c3ccccc3)[nH]c3ccccc23)C1 +Cc1nnc(NC(=O)CSc2ncnc3c2cnn3-c2ccccc2C)s1 +Cc1ccc2c(OCCN3CCC(Cc4cc5c(cc4F)OCC(=O)N5)CC3)cccc2n1 +CC(C)C(=O)NCc1ccc(Cl)c(C(=O)Nc2ncc[nH]2)c1 +O=S(=O)(c1ccccc1)C1CC2(c3ccccc3)NC1CCC2OCc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1cc(C#N)cc(-c2ccc(C3CC3NC3CCC(N)CC3)cn2)c1 +O=C(CNc1ccccc1)NN=Cc1c(O)ccc2ccccc12 +Cc1[nH]c(C(Cc2cn(C)c3ccccc23)NC(=O)C(CC(C)C)NC(=O)Nc2ccccc2)nc1C(=O)O +O=c1[nH]c(=O)n(C2CC(O)C(CO)O2)cc1Br +Cc1[nH]nc2c1C(c1cc(Br)cc(-c3ccc(Cl)s3)c1)(C(C)C)C(C#N)=C(N)O2 +CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)c(Br)n2)c(F)c1 +Oc1ccc2c3c1OC1C(Nc4ccccc4)CCC4(O)C(C2)N(CC2CC2)CCC314 +CN(CC(CCN1CCC(n2ccnc2)CC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +c1ccc(Nc2nc3c(N4CCCCC4)ncnc3s2)cc1 +NC(CNc1nc(-c2ccncc2)nc2c(Br)csc12)CC1CCCCC1 +NCCn1cc(S(=O)(=O)c2ccccc2)c2cccnc21 +NCCCNC(=O)c1ccc(NC(=O)CSC(=O)N2CCCc3cc(Cl)cc(Cl)c32)c(Cl)c1 +COc1ccc(-c2nnc(C(=O)C(NC(=O)Cn3c(-c4ccc(F)cc4)ncc(N)c3=O)C(C)C)o2)cc1 +CCN(CC)c1nc(C)nc2c(-c3ccc(Cl)cc3Cl)c(C)nn12 +O=C(CN1CCN(c2ccc(Cl)cc2)CC1)NC1C2CC3CC(C2)CC1C3 +Cc1cccc(-c2c(C(=O)c3ccccc3)oc3ccc4c(C)cc(=O)oc4c23)c1 +O=C(NC1CCCC1NC(=O)c1ccc2c(Cl)c[nH]c2c1)c1ccc(N2CCOCC2=O)cc1 +COc1cc(C(=O)c2cc(Cl)ccc2N)cc(OC)c1OC +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)CCCN(C)C)ncn3)cccc2s1 +CC(=O)OC1(c2ccccc2)CCN2CC(c3ccccc3Cl)CCC2C1 +COc1ccc(-n2cnc3ccc(-c4nnc(SCc5ccc(OC)c(C(F)(F)F)c5)o4)cc32)cc1 +O=C1c2ccc(Nc3ccc(F)cc3F)cc2CCc2ccc(OCCCO)cc21 +CN(C)CCNC(=O)c1ccc(C=NNc2ncnc3c2cnn3-c2cccc3[nH]cnc23)cc1 +Cc1nn(-c2ccccc2)c(C)c1C=NN1CCN(Cc2ccccc2)CC1 +Cn1cc(-c2ccc3nnc(Cc4cccc5c(=O)[nH]ccc45)n3n2)cn1 +CC1CN(Cc2c[nH]nc2-c2cc(C#N)c[nH]2)CCN1c1ccc(C(F)(F)F)cn1 +N#CC1(NC(=O)C(CC(=O)N2CCOCC2)CC2CCCC2)CCN(C2CCCCC2)C1 +COC1C(F)CN(C(=O)Cn2cc(C(C)=O)c3ccccc32)C1C(=O)NC1(c2ccc(Cl)cc2)CC1 +CC(C)(C)c1cccc(C=CC(=O)Nc2ccc3c(c2)OCCO3)c1 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1cnc(N2CCC(F)(F)C2)c(-c2cncnc2)c1 +N#Cc1cccc(NC(=O)N2CCCC2c2cccc(C(=O)Nc3ccc(CCN4CCOCC4)cc3)c2)c1 +COc1ccccc1-c1csc2nc(N3CCNC(C(N)=O)C3)nc(N3C4CCC3COC4)c12 +COc1ccc(-c2ccc3c(n2)N(C2=NC(=O)C(C)(C)S2)CCO3)cc1OC +Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OCCF)c(C3CC3)cn2)no1 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+CN(CC=Cc1ccc(-c2ccccc2)cc1)Cc1ccc2c(c1)OCCC2 +CN(Cc1ncc2ccccc2c1CNC(=N)N)C1CCCc2cccnc21 +O=[N+]([O-])c1ccc2c(c1)[nH]c1c3ccccc3nc3cccc2c31 +CN(C)CCOc1cc(-c2cn[nH]c2)ccc1NC(=O)C(N)c1ccc(Cl)cc1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1ncccc1[N+](=O)[O-] +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)COc2ccc(C(C)(C)O)cc2)CC(O)CC1O +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=O)C(F)(F)F)CC2 +NC(=O)c1ccc(NC2CCCCC2N)cc1Nc1cccc(-c2ccccc2)n1 +Nc1ccc(-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)nc1 +CC1(COc2ccc3c(c2)C2(COC(N)=N2)c2cc(-c4cccnc4)cc(F)c2O3)COC1 +Cc1cc(C)c(NC(=O)N(Cc2ccc(-n3nccn3)cc2)C2CCCCCC2)c(C)c1 +COc1ncc(Nc2ncccc2-c2nc(C)nc3[nH]cnc23)cn1 +COC(=O)C1(c2cccc(OCC3CCCCC3)c2)CC1C(=O)NO +CN(C)CCNC(=O)c1cccc2cc3c(nc12)-c1ccccc1S3(=O)=O +CC(NC(=O)C1(N)CCN(c2ncnc(N)c2-c2cn[nH]c2)CC1)c1ccc(Cl)cc1 +COc1ccc(C(C#N)(CCCNCCc2ccc(O)c(I)c2)C(C)C)cc1OC +CNC(=O)C=C1COc2cc(OS(=O)(=O)CCC(F)(F)F)ccc21 +CC1(C)OC(S)=Nc2ccc(-c3ccc(C#N)s3)cc21 +Clc1ccc2oc(NC(CN3CCSCC3)c3ccccc3)nc2c1 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+Cc1ccc(F)cc1Nc1nc2ccc(CC(=O)N3C(COC4CCC(C(=O)O)CC4)CCC3CN(C)C)c(F)c2o1 +O=C(O)c1n[nH]c2cc(Cl)c(-c3ccc(C4CCOCC4)cc3)cc12 +CCC(NC(=O)c1cc(C(=O)NC(C)c2cnccn2)n2c1COCC2)c1ccccc1 +Cc1nnc2n1-c1sc(C#CCn3c(=O)c4ccccc4c(=O)c4ccccc43)cc1C(c1ccccc1Cl)=NC2 +CC(C)(C)CN(C(=O)CCC(=O)N1CCN(S(C)(=O)=O)CC1)c1ccc(Cl)cc1C(O)c1ccccc1Cl +CCC1CN(c2ncc(C(=O)NC)nc2C)CCN1C1CCN(C(=O)c2ccc(Cl)nc2N)CC1 +CNc1nccc(-c2ccc(C(=O)NC(CO)Cc3ccc(Cl)cc3Cl)s2)n1 +Cc1nc2ccccc2nc1N1CCc2ncnc(Nc3ccc(C(C)(C)C)cc3)c2CC1 +CC1(c2nnc(-c3nn(-c4ccc(Cl)cc4Cl)c(-c4ccc(Br)cc4)c3Cn3cncn3)s2)CC1 +Cc1cc(OCC(C)C)ccc1C(C)Nc1nccc(N2C(=O)OCC2C(C)C)n1 +O=C(c1ccc(F)cc1)C1CCN(CC2CC3c4ccccc4Cc4ccccc4C3O2)CC1 +Cc1cc(N)nc(C)c1CNC(=O)c1ccn(S(=O)(=O)c2ccc3c(ccn3C)c2)c1 +Nc1cc(N)c2cc(CCc3ccc(C(=O)NC(CCCNC(=O)c4ccccc4C(=O)O)C(=O)O)cc3)ccc2c1 +Cc1ccc(N2CCN(CCC3CCC(NC(=O)C4CCCCC4)CC3)CC2)cc1C +Cc1ccccc1C#Cc1ccc2c(n1)CCN(C1CCCC1)C2=O +CC(=O)NC1C(N)C=C(C(=O)O)OC1C(=O)N(CCc1ccccc1)C(C)C +CC(C)Oc1ccc(-c2nnc(-n3cc4c(n3)CCN(CCCC(=O)O)C4)s2)cc1C#N 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+CC(NC(=O)c1cc(F)cc2ccn(Cc3cccc(Cl)c3)c12)c1ccc(C(=O)O)cc1 +O=C1C2C3C=CC(C4C=CC43)C2C(=O)N1CCCCN1CCN(c2cccc(Cl)c2)CC1 +N#CC(=Cc1ccc(Sc2ccccc2)o1)c1nc2ccccc2[nH]1 +CCc1cc(O)c(OC)c(C(=O)NCC2CCCN2CC)c1OC +Cc1ccc2oc(=O)c(C=Nc3ccc(S(=O)(=O)NC(=N)N)cc3)c(Cl)c2c1 +NC1CCN(c2ccc(N3Cc4cn(-c5ccc(Cl)cc5)nc4C3=O)cn2)C1 +Cc1cc(F)ccc1C1CN(C(N)=O)CCC1C(=O)N(C)Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC1CN(C(=O)OC2CCOC2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Cc1nn(C)cc1-c1nc2c(Oc3ccc(C(=O)NC4CCC4)cc3)c(Cl)cnc2[nH]1 +CCC(CC)NC(=O)C(NC(C)=O)C1CC(C(=O)O)CC1N=C(N)N +CC(O)(c1cncc(N2CCC3(CCOC3)CC2)c1)C(F)(F)F +COc1ccccc1CN=C(N)c1cc2cc(Cl)ccc2[nH]1 +CC1=Nc2cc(=O)n(S(=O)(=O)c3ccccc3)n2C(c2cccc([N+](=O)[O-])c2)C1=C(O)OC(C)C +CN1CC(Cc2ccccc2)(c2ccc(F)c(OCCNS(=O)(=O)c3cn(C)cn3)c2)C1 +FC1(F)CCN(c2cc(-c3n[nH]c4ccc(-c5cccnc5)cc34)ncn2)CC1 +O=C(Nc1ccccc1-c1nc2c(C(=O)O)cccc2o1)c1ccccc1 +CNc1cc(NC(=O)OC)ccc1Nc1c2ccc(Br)cc2nc2c(OC)cccc12 +O=C(O)CCCC(=O)NC1CCC2(O)C3Cc4ccc(O)c5c4C2(CCN3CC2CC2)C1O5 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+CCC(=O)c1ccc(F)c(C2CC2NC(=O)Nc2ccc(Br)cn2)c1O +CCC1CCCC(C2(CC(=O)N3CCC(N4CCCCC4)CC3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +COc1ccn2c(c1)nc1c2c(=O)n(CCC(C)C)c(=O)n1Cc1ccccc1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(C(=O)CCN)CC2)CC1 +Cc1ccc2c(c1)Oc1sc(Cl)cc1C(N1CCN(CC(C)(C)C(=O)O)CC1)=N2 +Nc1nc(N)c2ncn(CC3COP(=O)(OCC(F)(F)F)CO3)c2n1 +COc1ccc(Cl)c(-c2noc(C(C)C)c2COc2ccc(-c3ccc4c(C(=O)O)cn(C)c4c3)c(C)c2)n1 +CNc1ccc(-c2ccc3c(N4CCOCC4C)nc(N4CCOCC4C)nc3n2)cn1 +CCCCCCCCCCCC(=O)NC1CCc2cc(OC)c(OC)c(OC)c2-c2ccc(OC)c(=O)cc21 +C=C1COC2(CN(c3ncc(C(=O)O)s3)CCC2NC(=O)c2[nH]c(C)c(Cl)c2Cl)OC1 +CCNc1cc(C(=O)NC(Cc2ccccc2)C(O)CNCc2ccccc2)cc(N2CCCCS2(=O)=O)c1 +O=C1NC(=O)c2c1c1c3ccccc3ccc1c1[nH]c3ccccc3c21 +Cc1nc(C)c(CNc2nc(OCC#Cc3ccccn3)nc(Cl)c2C)s1 +COc1ccc(Oc2ccc(NC(=O)NC(Cc3ccccc3)C(=O)NCCCN3CCOCC3)cc2)cc1 +Cc1c(-c2cccc(O)c2)[nH]c2ccc(N3CCCCC3)cc2c1=O +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(Oc2cccnc2)n1 +CCCCCCc1nc2cc(C=CC(=O)NO)ccn2c1NCCC(=O)NC(C)(C)C +CC(=C[S+](C)[O-])n1c(C(=O)c2ccc(Cl)cc2)noc1=O +Cc1c(N(Cc2ccc(C(F)(F)F)cn2)S(=O)(=O)c2ccc(C(=O)O)cc2)ncc2ccccc12 +COc1ccc(N2N=C(S(C)(=O)=O)C3CCN(c4ccc(C5(CN6CCCC6)CC5)cc4)C(=O)C32)cc1 +N#CC1(NC(=O)C2CCCCC2C(=O)N2CCN(c3nc4ncccc4s3)CC2)CC1 +CCCc1ccc2c(c1)sc(=O)n2CCCCN1CCCCC1 +O=C1C2C3C=CC(C3)C2C(=O)N1c1ccc([N+](=O)[O-])c2ccccc12 +O=C(NC(C(=O)N1CCCC1B(O)O)c1ccccc1)c1ccnc2ccccc12 +COc1cccc2c(-c3ccc(O)c4c3CCNC4)ccc(O)c12 +CCN(C(=O)C(C)(C)C1(O)CCN(CCc2ccccc2Cl)CC1)c1ccccc1OC +CCNC(=O)C(=O)C(Cc1ccc(C)cc1)NC(=O)C(NC(=O)CCCCC1CCSS1)C(C)C +Cc1ccc(NC(=O)c2[nH]c(C3(C)CCCCC3)nc2CCC23CC4CC(CC(C4)C2)C3)cc1C(=O)O +Cc1ccc2c(c1)-c1nnc(-c3ccc(C4(N)CCC4)cc3)n1-c1cccnc1N2 +Oc1ccc(C(=C2CCCCCC2)c2ccc(O)cc2)cc1 +C=CCN(c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CCOC(=O)c1cnc(NCc2ccc(OC)cc2)n2nc(-c3ccco3)nc12 +Cc1cc2c(cc1C)-n1cnnc1CC(c1ccc(-n3c(C)nc4cnccc43)cc1)=N2 +CCN(CCCCCCNC1=CC(=O)C(NCCCCCCN(CC)Cc2ccccc2Cl)=CC1=O)Cc1ccccc1Cl +COc1ccc(-c2cc(NC(=O)C3Cc4ccc5ccccc5c4C3)[nH]n2)cc1OC +COc1c(OCC2CC2)ncnc1N1CCC(Oc2ccc(C(C)NC(=O)c3cnco3)cc2)C1 +O=C(Cn1cnc2cccnc21)N1CCN(c2sc(C(F)(F)F)nc2-c2nc3ccccc3[nH]2)CC1 +O=S(=O)(Nc1ccc(Cl)cc1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +CC(=O)c1nn(CC(=O)N2C(C(=O)NC3(C4CCCCC4)CC3)CC3CC32)c2cnccc12 +COc1ccc(C(=O)N2c3ccccc3Oc3cc(C#N)ccc32)cc1 +CC(=O)N1CCC(c2ccc(N3CCOc4ncnc(N)c4C3=O)cc2)CC1 +CS(=O)(=O)N1Cc2cc(Br)ccc2N(Cc2c[nH]cn2)CC1Cc1ccccc1Cl +Nc1ccccc1NC(=O)c1ccc(CN(CCO)Cc2ccc(-c3cccs3)cc2)cc1 +CN(c1cc(CO)ccc1Cl)c1nc(Nc2cc(N3CCOCC3)cc(S(C)(=O)=O)c2)ncc1F +Cc1cc(Nc2nn(Cc3ccc(F)cc3)c(=O)c3ccccc23)n[nH]1 +CCN(CC=CC#CC(C)(C)C)c1cccc2c1CCC(=O)N2 +COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OCc1ccc([N+](=O)[O-])cc1 +Cn1cc(-c2cn(-c3cccc4c(-c5ccc(C(N)=O)c(NCC6CC6)c5)cc(C(F)(F)F)nc34)cn2)cn1 +COCOc1c(Br)ccc2oc(-c3cn4nc(OC)sc4n3)cc12 +COc1ccc2cnc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3)nc2c1C(C)C +Cc1cc(C(C(=O)NC(C)C)N2C(=O)C(C3Cc4ccccc4C3)NC(=O)C2CC(C)C)oc1C +OCC1CCN(Cc2ccc(OCCCN3CCCCC3)cc2)CC1 +CSCCNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O +Cc1cc(C)cc(-c2cnc(-c3cccnc3)c(C(=O)N(C)Cc3ccc4c(c3)OCO4)c2)c1 +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)Oc1ccc2c(c1)[nH]c1ccccc12 +COc1c(Cl)cc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)cc1Cn1ccnn1 +CCn1cc(C(=O)N2CCC(c3cccc(CN)c3)CC2)c2cccc(C)c21 +COCCc1sc[n+](CCCCCCCC[n+]2csc(CCOC)c2C)c1C +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(N(C)c3ccncc3)cc2)cc1 +c1ccc2c(NCCCCCCCCNCc3ccncc3)c3c(nc2c1)CCCC3 +CC(C)(C)c1cccc(CNC2CS(=O)(=O)CC(Cc3ccc4[nH]cc(CC(F)(F)F)c4c3)C2O)c1 +O=C1CC2(C(=O)N1)C(=O)N(Cc1ccc(Br)cc1F)C(=O)c1cc(Cl)ccc12 +COc1ccc(C23CC2CN(CCCSc2nnc(-c4ocnc4C)n2C)C3)cc1 +CCC(C)(C)NC(C)C(O)c1ccc(C(F)(F)F)cc1 +COc1ccc(CNCC(NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)C(=O)NC(C)(C)C)c(C)c1 +CN(C)Cc1ccc2c(c1)CCC(N(C)C(=O)c1ccc(-c3cccnc3)cc1)C2 +CCCC(CCC)c1ccc(Cl)c2nc(Nc3c(C)cc(Cl)cc3OC)n(C)c12 +Cn1cc(S(=O)(=O)N2CCC(CNC(=O)c3ccc(Cl)cc3Cl)(CC3CC3)CC2)nn1 +O=C(Cn1cnc2cc([N+](=O)[O-])ccc2c1=O)NC(=O)NCc1ccccc1 +O=C(O)CNc1cc(-c2cccc(NCc3cccc(F)c3)n2)c(Cl)cn1 +CC(=O)N1CCN(C(=O)c2cc(Sc3cnc(Nc4cccc(Br)n4)s3)ccc2O)CC1 +OC(Cc1ccc(F)cc1)C1CCN(CCCc2ccccc2)CC1 +CCC12CC(C)(O)C(O)(c3nccs3)CC1CCc1cc(O)ccc12 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3ccc4c(-c5ccncc5)n[nH]c4c3)NC(=O)NC1=O)C2 +NC(=S)Nc1cccc(OCCCCCCCCNC(=S)Nc2ccc(Br)cc2)c1 +NC(=O)c1ccc2c(c1)nc(-c1ccccn1)n2C1CCCC(NC(=O)c2ccc(Br)s2)C1 +COc1cc(C(=N)N)cc2cc(CCCCCc3cc4cc(C(=N)N)cc(OC)c4o3)oc12 +CC(C)C1CCC2(CO2)C2C(=O)OCC(C(=O)OCc3ccc(-c4ccccc4)o3)=CC12 +CCCSCC1OC(n2cnc3c(NC4CCCC4)ncnc32)C(O)C1O +CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4c(c3)[nH]c3ccccc34)n2)c(=O)c1=O +CC(=O)N1CCCC1c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1 +COc1ccc(-c2snnc2-c2cc(OC)c(OC)c(OC)c2)cc1O +COc1cccc(-c2ccc(CC(CC(=O)NO)C(=O)NC3c4ccccc4CC3O)cc2)c1 +COc1nc(NCCCN2CCOCC2)nc(OC)c1NC(=O)c1ccc(Oc2cc3c(cc2C)CCC3(C)C)o1 +CNc1nc2cc(-c3cccc(C(=O)O)c3)sc2n2c(C)cnc12 +O=C(c1ccc(-c2ccccc2Cl)cc1)N(CC1CC1)CC1CCCO1 +O=C(c1ccccc1-c1ccccc1)N1CC(CN2CCC(c3ccccc3)CC2)C(c2ccccc2)C1 +O=C(Nc1nn[nH]n1)c1ccc(Cn2nc(-c3cc(Cl)cc(Cl)c3)cc2-c2ccc(OC(F)(F)F)cc2)cc1 +CCCCn1c(=O)[nH]c(=O)c2c(C(=O)OCC)cc(-c3cccs3)nc21 +O=CC(Cc1ccccc1)NC(=O)c1ccccc1C#Cc1ccccc1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCC3=CC(=O)CCC3(Cc3ccccc3)C2)cc1 +COc1cc2c(NC3CCN(C(C)C)CC3)nc(N3CCCN(Cc4ccccc4)CC3)nc2cc1OCCCN1CCCC1 +O=S(=O)(NCc1cnccc1-c1c(F)cccc1F)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(C)(C(=O)NC(N)=O)C1c2ccc(-c3ccc(C(=O)N4CCC(F)C4)cc3)nc2Oc2c(F)cccc21 +Cc1nc(N(C)c2ccc(N=[N+]=[N-])cc2)c2ccccc2n1 +Nc1nc(O)c2ncn(COCCCCP(=O)(O)O)c2n1 +CNCC(CC1CCCCC1)NC(=O)N1CCCC(C(OCCCOC)c2cccc(Cl)c2F)C1 +CCN1CCCC12CCN(C(=O)c1cc(Cc3n[nH]c(=O)c(C)c3C)ccc1F)CC2 +O=C(O)c1ccc(NC(=O)c2cc(Cl)c(Cl)cc2Oc2ccc(OC(F)(F)F)cc2)cn1 +Fc1cc(Cl)ccc1C(NC1CCN(c2c(F)cccc2F)CC1)c1cccnc1 +COc1ccc2nc(C)c3c(C)nc(-c4c(C)n[nH]c4C)n3c2n1 +NC1=NCCCCN1Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)Nc2ccc(Cl)cn2)cc1 +Cc1ccc(NC(=O)Nc2ccc(-c3ccnc4[nH]nc(N)c34)cc2)cc1 +O=S(=O)(NCC(c1cccnc1)N1CCN(Cc2ccccc2)CC1)c1ccc(Cl)cc1 +CN(C)C(=O)c1c(CNC(=O)c2cnn(C)c2)c(=O)c2ccc(Cl)cc2n1-c1ccccc1 +CCCCCCC=C1CC(CO)(COC(=O)c2ccc(C(F)(F)F)cc2)OC1=O +[O-][S+]1CC(O)C(O)C(O)CC(O)CC(O)C(O)C(O)C(O)C1 +CCc1cc(CC)n2nc(-c3ccc(OC)cc3)c(CC(=O)N(CC)CC)c2n1 +NS(=O)(=O)c1ccc(N=c2scc(-c3ccc(Br)cc3)n2C2CCCCC2)cc1 +O=c1c2c(O)cc(O)cc2ncn1-c1ccc(O)cn1 +COC(=O)c1c(F)cccc1-c1ccc(CNc2ccc(C(=O)N3CCN(C(=O)C(C)(C)C)CC3)cn2)c(F)c1 +CCNC(=O)C(c1ccccc1)N1CCN(c2ccc(NC(=O)c3ccccc3-c3cccnc3)cc2F)CC1 +CCc1[nH]c2nc(Sc3ccc4c(c3)C(=O)NC4)nc(N3CC4C(N)C4C3)c2c1Cl +O=C(Nc1cc(-c2ccc(O)cc2)cn(CC(F)(F)F)c1=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1 +CC1CN(Cc2ccc3c(-c4cnn(C)c4)cc(C(N)=O)nc3c2)CCO1 +Nc1nccnc1-c1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 +CC(C)COC(=O)N1CCC(C#N)C(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)C1 +CN(c1cncnc1)c1cc(C(=O)Nc2cccc(Cl)n2)ccc1F +CN1CCN(CCCNc2nccc(-c3c(-c4ccc(C(F)(F)F)cc4)nn4cc(C(F)(F)F)ccc34)n2)CC1 +CC(=O)SCC(C)C(=O)N(CC(=O)O)c1ccc(C(C)C)cc1 +CC(C)(C)OC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCCNc1ccnc2cc(Cl)ccc12 +Cc1cc(=O)[nH]c(C)c1C(=O)N1CC2CN(CCC(NC(=O)C3CCCC3)c3ccccc3)CC2C1 +O=C1C(=O)N(Cc2cc3ccccc3s2)c2ccc(I)cc21 +CN(c1ncnc2[nH]ccc12)C1CC(CS(=O)(=O)N2CCCC2)C1 +N=C(N)NCCCC(NC(=O)c1ccccc1-c1ccccc1)C(=O)NC(Cc1ccccc1)C(N)=O +COc1ccc(NCCNC(=O)C(CC2CCCCC2)NC(=O)c2cccc(C)c2)cc1 +COc1ccccc1NC(=O)Cn1cnc2sc(C(=O)Nc3ccc(F)cc3)c(C)c2c1=O +CCOc1ccccc1-c1cccn2nc(Nc3ccc4c(c3)CCN(CCS(C)(=O)=O)CC4)nc12 +Cc1ccc2ccc(N3CCC(Oc4nccnc4C4CCOCC4)CC3)nc2c1 +Cn1cc(-c2cnc(N)c(-c3ccc(C(=O)NC4CC4c4ccccc4)c(F)c3)n2)cn1 +Cc1c(CN2CCN(c3ccccc3)CC2)cnn1-c1ccccc1 +O=C(Nc1ncc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cn1)c1ccccc1 +Cc1c(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cnn1-c1ccccc1 +NC(CC(O)c1cc2ccccc2c2ccccc12)=NN=Cc1ccccc1 +Cc1c(CNc2ccc(C(=O)NC(CC(=O)O)C(=O)O)cc2)ccc2ncnc(N)c12 +c1ccc(-c2ccc3c(c2)OC(C2=NCCN2)CO3)cc1 +CNC(=O)C12CC1C(n1cnc3c(NC)nc(C#Cc4cccnn4)nc31)C(O)C2O +CCOc1cc(CN2CCC(NC(=O)c3ccc(NC)nc3)CC2)cc(OCC)c1-c1ccc(F)cc1 +COC1CCC2(CC1)Cc1ccc(C#CC3CC3)cc1C21N=C(N)N(Cc2nnc(C)s2)C1=O +CC(=O)OCc1cc(-c2ccc(S(C)(=O)=O)cc2)n(-c2ccc(F)cc2)c1C +NC(CNC(=O)c1cc(Br)c(-c2ccnc3[nH]ccc23)s1)c1ccccc1 +CC(C)CNC(=O)c1ccc2c(c1)N=C(c1ccc(Cl)s1)c1ccccc1S2 +COc1ccc2cc3[n+](cc2c1OCCCOc1ccc(-c2cc4ccccc4o2)cc1)CCc1cc2c(cc1-3)OCO2 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+CC(=O)N1CCC(c2nc(C)c(-c3cc(C(=O)N4CC(c5ccc(C#N)cc5)C4)ccc3C)[nH]2)CC1 +CC(C)(C)NOc1ccc(C(F)(F)F)cc1C(=O)N=c1sc(C(C)(C)C)nn1CC1CCC1 +Cn1cc(-c2ccc(-c3cncc(F)c3N3CCC4(CC3)CNC(=O)O4)cc2)cn1 +CC(Cc1ccc(O)cc1)NCC(O)COc1ccc(O)cc1 +Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4ccnc(C(F)(F)F)c4)c(Cl)c3)c21 +Cc1cc(COc2ccc(C(=O)NC3CN(C(C)(C)C)CCC3C(=O)NO)cc2)c2ccccc2n1 +Cc1ccccc1Oc1nc(Nc2ccc(C#N)cc2)nc2ccccc12 +CCC(CN1CCOC(C)(C)C1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +CC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCN(C)C)c1ccccc1 +COc1ccc(C)n2nc(CCc3cn(C)c(-c4cccs4)n3)nc12 +Nc1ccccc1NC(=O)c1ccc(CNCc2nc(-c3ccc(F)cc3)no2)cc1 +Nc1ccccc1NC(=O)c1ccc(CNc2cc(-c3ccccc3)[nH]n2)cc1 +COc1cccc(CNC(=O)c2cc(-c3nnn(Cc4ccc(C(=O)O)cc4)n3)ccn2)c1 +CC(C)(O)c1nc2cc(Cl)ccc2n1C1CCC(NCC2Cc3ccc(C(F)(F)F)cc3C2)CC1 +CCCCC(CC(CCc1ccc(Cc2ccccc2)cc1)C(=O)NC(C(=O)Nc1ccccc1)C(C)(C)C)C(=O)O +C#CCn1cc(-c2cnc(N)c3c(-c4ccc(Oc5ccccc5)cc4)csc23)cn1 +Cc1coc(-c2cccc3c2CCN2C(=O)CN=C(n4cnc(C5CC5)c4)C=C32)n1 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+O=C(Cn1c(-c2ccccc2)nc2ccc(-c3cccc(CN4CCCC4)c3)cc2c1=O)NCC1CC1 +Cc1c(C)c2ccc(OCC=Cc3ccccc3)cc2oc1=O +C=CC(=O)Oc1ccccc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2OC)ncc1Cl +Cn1c(=O)cc(NC2CCN(Cc3ccc4c(c3)OCO4)CC2)c2cc(OC(F)F)ccc21 +Cc1cc(C2=CCN(S(=O)(=O)CC(=O)NO)CC2)ccc1-c1ccccc1 +Nc1cccc(-c2cccc(Nc3nccc(C(F)(F)F)n3)c2)c1 +CCCC(Oc1ccc(-n2cc3cccc(Cl)c3n2)cc1)c1ccc(C(=O)NCCC(=O)O)cc1 +Cc1nnc(Nc2cc(C(=O)NC3CC3)ccc2Cl)c2cnn(-c3c(F)cccc3F)c12 +O=C(c1ccc(F)cc1)N1CCN2C(=O)c3ccccc3C12c1cccc(Cl)c1 +Cc1ccc(C2CC2COc2nc(C)ncc2-c2ccc(=O)n(C(C)C)c2C)nc1 +COCCN1Cc2cccc(C(=O)Nc3cccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)c3)c2C1=O +CCc1ccc(-c2ccc(CN3CC(C(=O)O)C3)cc2)cc1 +CS(=O)(=O)c1ccc(-c2[nH]c3ccc(Cl)cc3c2-c2ccccc2Cl)cc1 +C=C(C)n1c(=O)n(CCN2CCC(N(C(=O)CC)c3cc(Cl)ccc3Cl)CC2)c2ccccc21 +COc1cc(-c2cc(OC(C)C3CNC(=O)C3)c3cccnc3c2)ccc1C(F)(F)F +O=C(Nc1nc(-c2ccc(F)c(C(F)(F)F)c2)ns1)c1ccc(Nc2cc(N3CCC3)ncn2)cc1 +CC(C=CC1CC1(C)c1ccc2c(c1)C(C)(C)CCC2(C)C)=CC(=O)O +CC(C)CCn1c(=O)c(C2=NS(=O)(=O)c3cc(OCC(=O)N(C)C)ccc3N2)c(O)c2cccnc21 +O=C(Nc1nc(-c2ccccc2)nc2c1nnn2Cc1ccccc1)c1ccc(Cl)cc1 +Cc1sc2nc(NC(=O)CCCc3ccccc3)sc(=O)c2c1C +CC12COS(=O)OC1CCC1(C)C2CCC2CC3CC21CCC3(O)CO +O=C(Nc1ccc(Cn2cncn2)cc1)c1ccccc1NCc1ccncc1 +CCOc1ccccc1CN1CCN(Cc2[nH]c3ccccc3c2C)CC1CCO +Cc1ccc(C)c(Cn2cc(CCNc3ncnc4c3ncn4C3OC(C(=O)NC4CC4)C(O)C3O)c3ccccc32)c1 +O=C1NC(=O)c2c1c(-c1c(Cl)cccc1Cl)cc1c2c2cc(O)ccc2n1CCCC(=O)N1CCOCC1 +CC(C(=O)OC1CN2CCC1CC2)(c1ccccc1)c1ccccc1 +COCC(O)Cn1c(=O)cnn(-c2ccc(Cl)c(C(=O)NCC3(O)CCCCCC3)c2)c1=O +O=C(NO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1ccc(I)cc1 +COc1ccc(C2CC(=O)N(Cc3ccc(-c4ccno4)cc3)C2)c2c1oc1ccccc12 +CC1CN(CC(Cc2ccccc2)C(=O)NC(Cc2ccc3ccccc3c2)C(=O)O)CCC1(C)c1cccc(O)c1 +C=CCN1CC2C(Oc3ccccc3)CCC1CN2Cc1ccc(OC)cc1OC +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4ccc(C(F)(F)F)cc4)cc3)nc2c1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(C3CCC(F)C3)n2)cc1OC(F)F +Cn1cc(-c2cnc(N)c(-c3ccc(C(=O)NCc4ccsc4)c(F)c3)c2)cn1 +CCON=C(CCN1CCN(c2cccc(OCC)c2)CC1)c1ccccc1 +COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1cccc(Cl)c1F)C2=O +CCSC(=O)N1CCC(Oc2ncnc3c2CCN3c2ccc(S(C)(=O)=O)cc2F)CC1 +CC1Cc2ccccc2N1C(=O)CC1CCN(Cc2ccc(F)cc2Cl)CC1 +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)Nc3ccccc3C(=O)O)cc12 +Cc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CC(N)c3ccccc3)c2=O)c1F +COC1CC2CCC(C1)N2c1nc(-c2cccc3[nH]cc(C)c23)nc2c1CN(c1cc(C(C)C)ccc1C)CC2 +CC(C)N(CC(O)COc1ccc(C(=O)c2ccccc2)cc1)C(C)C +O=C1OCc2cc(CCN3CCN(C(=O)Cc4ccc(-n5cnnn5)cc4)CC3)cc(Cl)c21 +OC1CCCN(c2ccncc2Nc2ncc3ccc(-c4ccccc4Cl)nn23)C1 +CCOC(=O)c1nn(-c2ccccc2)c(=O)c2c(N)scc12 +CC1c2ncn(-c3cnccn3)c2CCN1C(=O)c1cccc(C(F)(F)F)c1Cl +CCCCn1cc2c(nc(NC(=O)Nc3ccc(C(F)(F)F)cc3)n3nc(-c4ccco4)nc23)n1 +Cc1c(N(CCC2CC2)S(=O)(=O)c2ccc(C3=NOS(=O)N3)cc2)sc2ccccc12 +CC(C)NCCOc1cccc2c1ccn2S(=O)(=O)c1ccccc1 +COCCC(C)(C)NC(=O)c1cnc(C2CC2)c(OCC2CC2)n1 +Fc1ccc(CN2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)nc1 +O=C(O)CC1CCC2(CCN(c3ccc(-c4nc5cc(C(F)(F)F)ccc5[nH]4)cn3)CC2)O1 +CN(C)CCNC(=O)c1cc2c3ccccc3n(C)c2c2cccnc12 +C#Cc1cc(Nc2ncnc3cc(O)c(OCCCCCCC(=O)NO)cc23)ccc1O +O=C(O)CC(=O)N1CCCN(C(=O)N2CCC3(CC2)CCN(c2ccncc2)C3)CC1 +CCCCc1ccc(C(=O)c2cn(CCC)c3ccccc23)c2ccccc12 +CCCc1nc2c(C)cc(C)nc2n1Cc1ccc2c(-c3nnn[nH]3)cc3ccccc3c(=O)c2c1 +N#Cc1ccc(CSc2ncnc3c2ncn3C2OC(CO)C(O)C2O)cc1 +CCCCNC(=O)N1CCC(c2cc(C)nn2-c2ccc(S(C)(=O)=O)cc2)CC1 +CN1CCCn2nc(C(=O)NCc3ccc(F)cc3)c(O)c2C1=O +CC#Cc1cncc(-c2cc3c(cc2C)CC2(CCC(OC)CC2)C32N=C(C)C(N)=N2)c1 +CC1CN(c2nnc(Cc3ccccc3)c3ccccc23)CCN1c1ccc(C#N)cn1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OCC4(C)CC4)c3)C2)cc1 +[C-]#[N+]c1ccc(N2C(=O)C3(CCC3)N(c3ccc(O)cc3)C2=S)cc1C(F)(F)F +Cn1c(CO)cc2ncnc(Oc3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)c(Cl)c3)c21 +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(Cl)c3)n3c2CCOC(C)C3)ccn1 +CCCC1(CCc2ccc(F)cc2)CC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)=C(O)O1 +CCc1cc2c(cc1Cn1c(C(=O)O)c(Cc3cccc(C(=O)O)c3)c(=O)c3cc(OCCCO)ccc31)OCO2 +COc1ccc2c(c1)C1OC1Cc1cc(OC)c(OC)c(OC)c1-2 +CNCC(=O)NC(Cc1ccc(Cl)cc1Cl)C(=O)N1CCN(c2ccccc2C(=O)CC(C)C)CC1 +O=C(CN1CCN(CCO)CC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 +COc1ccc(CCN2CCN(CCc3ccc(OC)cc3)CC2)cc1 +Nc1nc(NCC2CCC3CN(c4ncccn4)CCN3C2)nc2nc(-c3ccco3)nn12 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(-n5ccnc5)cc4F)nc23)N1 +CC1CN(Cc2ccc(N(C)C(=O)c3ccc(-c4cccc(C#N)c4)cn3)cc2)CCN1 +C=C(COCC(C)C1CCC2C(=CC=C3CC(O)CC(O)C3=C)CCCC21C)C1=CCCCC1(C)C +N#Cc1ccc(OCc2ccsc2)cc1OC(C(=O)O)c1cccc(Cl)c1 +CC(C)C1CCC(N2CCC(N3c4ccccc4CN(CC(=O)OC(C)(C)C)S3(=O)=O)CC2)CC1 +Oc1ccc(-c2csc(-c3ccc(O)cc3Cl)c2)c(Cl)c1 +Cc1ccc(CNCC2(F)CCN(C(=O)c3ccc(Cl)s3)CC2)nc1 +COCc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3c(F)ccc(F)c3Cl)cc2[nH]1 +COc1ccc2ncc(C#N)c(CC(O)C34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +O=C(Nc1ccc(-n2cnc3ccccc32)cc1)Nc1cccc(C(F)(F)F)c1 +CCOC1N(C2CC(N=[N+]=[N-])C(CO)O2)C(=O)NC(=O)C1(C)Br +CCOc1ccc(-n2nnc3cc(NCc4ccc(CC)cc4)ccc32)cc1 +O=C(O)c1cccc2c(=O)cc(-c3ccc(OCc4ccc5ccccc5n4)cc3)oc12 +COc1cc(C(=O)c2ccc(OC(C)C)c(N)c2)cc(OC)c1OC +CCOC(=O)c1[nH]c(C)c2cnnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c12 +CCc1nn(C)c2c1CN(c1ncnn3c(C)nc(C4CCOCC4)c13)CC2 +CCNC(=O)Cn1c(-c2cccc(Cl)c2)nc2ccc(OCCCN3CCCCC3)cc2c1=O +CC(C)(C)OC(=O)N1CCC(NC(=O)c2nc3c(C(N)=O)cccc3[nH]2)CC1 +CN1CCC(OC(=O)C(C)(c2ccccc2)c2ccccc2)C1 +CC1NC(c2c[nH]c(=O)c(C(F)(F)F)c2)=NC1(c1ccc(F)cc1)c1ccc(F)nc1 +NC(=O)c1c(-c2ccc(NC(=O)Nc3ccccc3)cc2)nsc1NC(=O)NCCCN1CCOCC1 +Cn1ncnc1-c1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1 +COC(=O)n1c(=O)n(-c2ccc(C#N)cc2F)c2c3cc(OCc4ccccc4)c(OC)cc3ncc21 +COCCN1CCN(c2cc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)ccn2)CC1 +CCc1nc(-c2ncn3c2CN=C(c2ccccc2)c2cc(Cl)ccc2-3)no1 +COC(C(=O)O)C1CCc2cc(OCCc3nc(-c4ccccc4)oc3C)ccc21 +CCOC(=O)CCN1CCN(CCOC(c2ccccc2)c2ccccc2Cl)CC1 +CC1CCN(C(=O)C(C)NC(=O)c2c[nH]c3ncc(C4CC4)nc23)C1 +CNC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3cc(NC(=O)c4ccc(Cl)cc4)c(F)cc3F)cc1CC2 +NC(=O)c1nnc(NC2CCCCC2N)nc1Nc1cccc2nn(C(F)F)cc12 +COC1CCN(c2nccc(Nc3cc4c(cn3)ncn4C3CCC3)n2)CC1 +COc1cc(CCCOC(=O)C2CCCCN2S(=O)(=O)c2ccccc2)cc(OC)c1 +Cc1ccc(-c2ccncc2)cc1NC(=O)c1ccc(OCc2ccccn2)cc1 +CCNc1nc(Nc2cc3c(cc2Cl)c(C(=O)N2CCOCC2)cn3C)ncc1C(F)(F)F +Oc1nc(NCc2ccccc2)nc2ccc3c(F)cccc3c12 +O=C(OC1C[N+]2(CCCc3cccs3)CCC1CC2)C(O)(c1cccs1)c1cccs1 +COc1ccc(NCc2ccc(C(=O)Nc3cc(-c4cccs4)ccc3N)cc2)cc1OC +O=C(O)CC(Cc1ccc(-c2cccc(Cl)c2)cc1)NC(=O)C(F)(F)C(F)(F)C(=O)O +CCOC(=O)c1cc2c(C#Cc3cccc(Cl)c3)nc(C)cn2c1 +Oc1cccc(-c2ccc3c(-c4cccc(O)c4)c(O)ccc3c2)c1 +CC#CCOc1ccc(C(=O)NCC(C(=O)NO)N2CCN(S(C)(=O)=O)CC2)cc1 +O=C(CCN1CCC23CCCCC2C1Cc1cc(O)ccc13)c1cccs1 +CN1C(=C2C(=O)OC(C)(C)OC2=O)Sc2ccccc21 +O=C(Nc1cccc(Oc2ccc3nc(NC(=O)C4CCOCC4)cn3n2)c1)c1cccc(C(F)(F)F)c1 +Oc1ccccc1Nc1nccc(-c2c[nH]c3ncccc23)n1 +COc1cc(-c2cccc(C(=O)NC3CCCCC3)c2)cc(C=O)c1O +Cc1cc(C)c(OCc2ccsc2S(=O)(=O)Nc2onc(C)c2Br)c(C)c1 +CC(C)Nc1c(C(N)=O)nnc2cc(N3CCN(C)CC3)ccc12 +Cn1nc(-c2ccccc2)c2c1NC(=O)C1CCCCC21 +CC(c1nc2c(oc3ccc(Br)cc32)c(=O)[nH]1)N1CCN(C)CC1 +O=C(C1CCN(Cc2ccncc2)CC1)N1CCN(c2ccccc2)CC1 +O=C1NCC2(CCNCC2)c2[nH]c(-c3ccnc(-c4cccc(C(F)(F)F)c4)n3)cc21 +COC1CCC2(CC1)Cc1ccc(C#CC3CC3)cc1C21N=C(N)N(CC(=O)OC(C)C)C1=O +CCOC(O)=C1C(C)=NC(C)=C(C(=O)OCCN(C)Cc2ccccc2)C1c1cccc(-n2ccnc2)c1 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+CC(C)C1=Cc2ccc3c(c2C(=O)C1=O)CCCC3=O +COc1ccc(CC(N)C(=O)NC2C(CO)OC(n3cnc4c(N(C)C)ncnc43)C2O)cc1 +Cc1nc2ccccc2n1Cc1ccc(CNC(=O)C(O)C(O)C(=O)N2CCCC2c2ccncc2)s1 +CCc1nc(CN2CCN(c3cccc4[nH]c(-c5ccc(C(C)(C)C)cc5)nc34)CC2)cn1C +COc1ccc(Cn2cc(-c3ccc(C(=O)NCCCCN4CCc5cc(OC)c(OC)cc5C4)cc3)nn2)cc1 +CCOC(=O)N1C2CCC1CC(c1ccnc3c(-c4ccc(C)c(O)c4)c(-c4ccncc4)nn13)C2 +COc1cccc(Cn2nc(C(F)(F)F)c(Cc3ccc4c(c3)OCO4)c2OCC(=O)O)c1 +CCC1C(C)CC2C(=O)OC(C)C2C1C=Cc1ccc(-c2cccc(Cl)c2Cl)cn1 +N=C(N)c1ccc(O)c(OCC(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +CNC(=O)c1c(NC(=O)c2nc(C3CC3)cnc2Nc2cncnc2)cnn1CC1CCO1 +CCOC(=O)N1CCC(N2CCCC(NC(=O)c3ccccc3C)C2)CC1 +COC(=O)N1CC2CC3CC31C(=O)NC(CCCNC(=N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)N2 +CNc1cccc(CCOc2ccc(CC(NC(=O)c3c(F)cccc3Cl)C(=O)O)cc2)n1 +O=S(=O)(Nc1ncns1)N1CCc2c(cccc2-c2ccc(C(F)(F)F)cc2N2CCOCC2)C1 +CCCCc1ccc2[nH]c(-c3ccc(C(F)(F)F)cc3)c(C=NNC(=O)c3ccccc3)c2c1 +N#CCn1cc(-c2cc3c(cn2)cnn3-c2cccc(N3CCCNCC3)n2)cn1 +Clc1cccc(COc2nc(N3CCNCC3)nc3ccsc23)c1 +COc1c(C)cc(C(=O)N2CCC(CCN3CCC(C(N)=O)(c4ccccc4)CC3)(c3ccc(Cl)c(Cl)c3)C2)cc1C +CCC(C(=O)Nc1ccc2cc(C(=O)NO)sc2c1)c1ccccc1 +CC(C)c1cc(-c2cc(-c3cc(C(C)(C)C)c(O)c(C(C)(C)C)c3)[nH]n2)cc(C(C)C)c1O +CCc1nc2c(C)cc(C)nc2n1C1CCCCc2cc(-c3ccccc3-c3nn[nH]n3)ccc21 +CCCCOc1ccc(CNc2ccc3c(c2)ncn3-c2ccc(OC)cc2)cc1 +CC(C)CCn1ccc(-c2ccc(OC3CCOCC3)c(Cl)c2)c(C#N)c1=O +O=C1c2ccccc2C(=Cc2c[nH]c3ccccc23)c2sccc21 +Cn1cc(NC(=O)c2cnn3ccc(N4CCNCC4)nc23)c(C(F)(F)F)n1 +Cc1c2ccccc2nc2c1c1cc(NC(=N)N)ccc1n2CCN(C)C +C=C1C(=CC=C2CCCC3(C)C(C(C)OCC(=O)NCC(F)(F)C(F)(F)F)=CCC23)CC(O)CC1O +O=C1Nc2ccc(Cl)cc2C1=C1Nc2ccccc2C1=NO +CN(C)c1ccc(C=CC(=O)C=Cc2c(Cl)cccc2Cl)cc1 +c1cc(C2CCC3(CC2)OOC2(O3)C3CC4CC(C3)CC2C4)ccc1OCCN1CCOCC1 +COc1ccc(Cn2c(C)cc3c(c2=O)C=C2CCC(C(C)Cn4cnc(N)c5ncnc4-5)CC2O3)cc1 +Cc1cc(-c2nc(-c3cc(F)c(OC4CNC(=O)C4)cc3Cl)no2)cc(NC(C)C)n1 +N#Cc1cnc2c(Br)cc(NCc3cn(Cc4cccnc4)nn3)cc2c1Nc1ccc(F)c(Cl)c1 +CC1CC(=O)NN=C1c1ccc2nc(-c3ccccc3)oc2c1 +CCOC(=O)c1cn2ccc(-c3noc(C4CCCCN4C(=O)COc4ccccc4)n3)cc2n1 +COc1ccc(-c2ccc(F)c(F)c2)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +FC(F)Oc1ccc2c(c1)CN1CCC2(c2ccc(Cl)c(Cl)c2)CC1 +NC(=O)c1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CC2CCCN2)CC1 +O=C(Cc1cccc2ccccc12)N1CCC(CNCCCCNCCN2CCCCC2)CC1 +N#Cc1c(-c2ccccc2)cc(N2CCN(C3CCCCC3)CC2)n2c1nc1ccccc12 +CN1C(=O)NCc2c(NC(=O)NC3CC(C)(C)Oc4c(F)cccc43)cccc21 +Cc1cc(F)ccc1NC(=O)Cc1nc(N2CCOCC2)cc(=O)[nH]1 +COCCCn1cc(Cl)c2cnc(C(C)N(C(=O)C3CNCCO3)C3CC3)cc21 +CC(=O)Nc1cccc(C2CCN(Cc3ccc(C(=O)c4nc5ccccc5n4-c4ccc(C#N)cc4)cc3)CC2)c1 +Cc1ccc(OCc2cc(C)c3c(c2C)CCN(C2CCOCC2)C3)c(-c2cccc(N3CC4CC4(C(=O)O)C3)n2)c1 +CCN(CC)CCCC(C)Nc1ccnc2cc(OC(F)(F)F)ccc12 +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)CSCC)CC2)cc1 +COc1ccccc1-c1csc2nc(N3CCC(C(N)=O)C3)nc(N3C4CCC3CC(OC)C4)c12 +Cc1ccc(Cl)cc1N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 +CC1(c2cc(NC(=O)c3ccc(F)cn3)ccc2F)CS(=O)(=O)C2(CCCC2)C(=N)N1 +CCN(CC(O)(CNC(=O)c1cnn(-c2ccc(F)cc2)c1N)C(F)(F)F)C(=O)c1ccccc1S(C)(=O)=O +Cc1cc(Nc2nc(-c3cccnc3)cn3c(-c4cn[nH]c4)cnc23)sn1 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+CC(=O)C(Cc1cccc(-c2cc(C(C)(C)S(C)(=O)=O)cc3cccnc23)c1)c1ccc(S(C)(=O)=O)cc1 +CN(C(=O)Cn1c(=O)n2c3c(cc(-c4ccccc4)cc31)OCC2)c1ccccc1 +NCC(c1cccc(C(F)(F)F)c1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1 +COc1ccccc1C(=O)Nc1cc2cc(C)c(=O)n(C)c2cc1N1CCCC1 +COc1ccc(O)c(C=NCCc2ccc(S(N)(=O)=O)cc2)c1 +Fc1cc(Oc2cccnc2)cc(-n2nnc(-c3ncc[nH]3)n2)c1 +CC1(C)OC(NC(CCO)c2ccccc2Cl)=NS(=O)(=O)C1(C)C +CC(C)(C)CN1CCC2(CC1)CN(c1ccccc1NC(=O)Nc1nc3ccc(F)nc3s1)c1c(O)ccc(Cl)c12 +COC(=O)c1cc2cc(NCc3c(C)cccc3Cl)cnc2[nH]1 +CC(O)CN1CC(C)(C)C(Oc2ccc(C#N)c(C(F)(F)F)c2)C1=O +Cc1cc(C)cc(Sc2c(C(C)C)c(=O)[nH]c(=O)n2Cc2ccccc2)c1 +N=C(N)c1cccc(CC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCCC2C(=O)O)c1 +CN(Cc1ccc(Cl)cc1)C(=O)C(CCN1CCC2(CC1)OC(=O)N(C)c1ccc(F)cc12)c1ccc(Cl)c(Cl)c1 +OCC1CC(O)CCN1CCc1ccc(Nc2nc(-c3ccccc3Cl)cs2)cc1 +COc1ccc(CC(NC(=O)C(NC(=O)C(Cc2ccc(OC)cc2)NC(=O)c2cc(Cl)ccn2)C(C)C)B(O)O)cc1 +C#CCNC(=O)c1cnc(Nc2ccc(C#N)cc2)cc1Oc1c(C)cc(C)cc1C +CCCCCn1c(C)c(C(=O)Cc2ccc(OC)cc2)c2ccccc21 +COc1ccncc1-c1ccc2cc(NC(=O)C3CC3)ncc2c1 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+O=C(NCCCCN1CCCC1)C1C(C(=O)Nc2nc(Br)cs2)C2C=CC1C21CC1 +COc1ccc(Cc2c[nH]c3c(OC)c(OC)c(OC)cc23)cc1O +O=C1N(Cc2ccccc2)C(Cc2ccc3c(c2)OCO3)C(O)C(O)C(Cc2ccc3c(c2)OCO3)N1Cc1ccccc1 +COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(Cl)cc4)cc3)c(=O)c2cc1Cl +Nc1ncccc1-c1nc2ccc(-c3cccc(N4CCS(=O)(=O)CC4)c3)nc2n1-c1ccc(C2(N)CCC2)cc1 +CCN1CCCC1CNC(=O)c1c(O)c(C)cc(C)c1OC +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CS(C)(=O)=O)c4ccccc4)ncc23)ccn1 +O=C(Nc1ccc(Cl)cc1)C1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccc(C(F)(F)F)cc2)c1 +Cc1ccc(C)c(NCc2cnc3nc(N)nc(N)c3c2C)c1 +COC(=O)CCCN1C(=O)c2ccccc2NC1c1ccc2c(c1)OCO2 +CCCCC1=NC2(CCCCCC2)C(=O)N1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCCCCCCCCCCCCCCC(=O)OC1Cc2c(O)cc(O)cc2OC1c1cc(O)c(O)c(O)c1 +Cc1ccccc1NS(=O)(=O)c1ccc2[nH]cc(C(=O)NC3CCCC(C)C3C)c(=O)c2c1 +CS(=O)(=O)c1ccc(-c2nc(SCc3cccs3)cc(C(F)(F)F)n2)cc1 +COC(Cn1c(SCCC(=O)O)nc(-c2ccc(F)cc2)c1-c1ccnc(NC(C)=O)c1)OC +CCOC(=O)CC1N=C(c2ccc(Cl)cc2)c2c(sc(C)c2C)-n2c(C)nnc21 +COC(=O)c1cccc2c1C(=O)C=C1N(C(=O)OC(C)(C)C)CC3CC123 +O=C(Nc1ccc(Cl)cc1)c1cccc(O)c1NC(=O)c1sc2ccccc2c1Cl +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4cccc5c4OCCCO5)nc23)N1 +CC(C)CCN(CC(O)C1Cc2ccc(cc2)OCCCCCC(=O)NC(C(C)C)C(=O)N1)NC(=O)NC1CCCCC1 +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCn6ncnc6C5)ncn4)c3c2)cn1 +Cc1nc(O)c2c(ccc3[nH]c(Nc4c(Cl)cccc4Cl)nc32)c1C +O=C(O)c1ccc2c(c1)C(=CCn1cnc3ccc(Cl)cc31)c1ccccc1CO2 +CCOC(=O)C1=C(c2ccc(Cl)cc2)N=C(C)C(=C(O)OCC)C1C=Cc1ccccc1 +N#Cc1cc(F)cc(-c2ccc3c(c2)C2(CCCCC2)C(S)=N3)c1 +O=C1C(N2CC2)=CC(=O)c2c(OS(=O)(=O)C=Cc3ccccc3)cccc21 +CC(C)(CNC(=O)c1ccccn1)NCC(=O)N1CC(F)CC1C#N +c1cnc(N2CCN(CCCNC3=Nc4ccccc4OC3)CC2)nc1 +Cc1cc(-c2c(-c3ccccc3)c3cc([N+](=O)[O-])ccc3[nH]c2=O)on1 +O=c1[nH]c(=O)n(C2OC(COP(=O)(O)CP(=O)(O)O)C(O)C2O)cc1I +CC(=O)NC(C)C#Cc1cnc(Oc2cccc(OCC(C)C)c2)s1 +Clc1cccc2c1CC2CCN1CCN(c2cccc3c2OCCO3)CC1 +Cc1cc(CN(CC2CCC(C(=O)O)CC2)C2CCc3cc(Cl)ccc32)ccc1OCCN1C(=O)CN(C)C1=O +Cc1nn(C)c(O)c1C(=O)c1ccc2nc(C)n(-c3ccccc3F)c(=O)c2c1 +CC(NCc1cc2cccc([N+](=O)[O-])c2[nH]1)c1cccc2ccccc12 +COCCN(C)C1CCN(C(=O)Cn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +CC(C)(C)Cc1nc2c(n1CC1CC1)CCN(S(C)(=O)=O)C2 +COCC(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NC(C)C +Cc1c(C(=O)c2ccccc2F)c2cccc3c2n1C(CN1CCOCC1)CO3 +Cc1ccn2c(NC(C)(C)CC(C)(C)C)c(-c3ccccc3OC(=O)C34CC5CC(CC(C5)C3)C4)nc2c1 +COc1ccc(N(C)C(=O)CNC(=O)C=Cc2ccc(C(F)(F)F)cc2)c(Cl)c1COc1cccc2ccc(C)nc12 +Cc1cccc(C)c1NC(=O)c1ccc2nc(NC(=O)NC(C)(C)C)sc2c1 +Cn1c(=O)c2c(nc(SCCc3cccc(C(F)(F)F)c3)n2C)n(C)c1=O +O=C(CSc1nnc(Nc2ccccc2)s1)NN=Cc1ccc(-c2ccccc2Cl)o1 +CC12C=CC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(O)C(O)C(=O)NCc1ccccc1 +CNC(=O)c1ccc(N2C(=S)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C2(C)COC)cc1F +N#CN=C(NCCCCCC(Cc1ccccc1)C(=O)NOC1CCCCC1)Nc1ccncc1 +Cc1ccc(-c2cc(C(=O)NC(C)CO)cc(-n3c(=O)oc4ccccc43)c2)nc1 +CCCN(CCC)C(=O)Cc1c(-c2ccc(C)cc2)[nH]c2ccc(C)cc12 +CCC(CC)c1cc(C)n2nc(-c3cnc(N(C)C)cc3C)c(C)cc12 +O=C1C(=NO)c2cc(F)ccc2N1Cc1cc(F)cc2c1OCOC2 +CN(Cc1ccc(F)cc1)c1cc(O)c(=O)[nH]n1 +COc1ccc(Cn2cnc3c4nc(=O)n(Cc5ccc(Br)cc5)c-4ncnc32)cc1 +NC(=O)C1CCN(c2nc(-c3ccnc(NC4CCOCC4)c3)cc3cnccc23)CC1 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+O=C(Nc1cc2c(c(C(=O)NCc3ccccc3C(F)(F)F)c1)OCC2)c1ccccc1C(F)(F)F +CCS(=O)(=O)c1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CC3C3CC43)c(F)c2)cc1 +CC(Cc1ccccc1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1 +Cc1nc(NC2CCCC2)sc1-c1nc(Nc2ccc(N3CCN(C)CC3)cn2)ncc1F +O=C(C[n+]1ccn(C23CC4CC(CC(C4)C2)C3)c1)c1ccc2ccccc2c1 +Cn1cc(-c2cnc3[nH]cc(-c4cnn(Cc5cccc(Cl)c5)c4)c3c2)cn1 +CCCCC(C=NNC(=O)N1CCc2ccccc21)NC(=O)OC(C)(C)C +NCc1c(-c2ccccc2Cl)ccc2ncn(Cc3ccccc3)c12 +CN(C)c1nc2sc3c(c2c(=O)o1)CCN(Cc1ccccc1)C3 +COc1ccc2c(c1)CCN(C)CCc1c([nH]c3ccccc13)C2 +CCCCCCCNC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1 +O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2ccc(Cl)cc2Cl)CC1 +Cn1nc(C(F)(F)F)c(CS(=O)(=O)C2=NOC(C)(C)C2)c1OC(F)F +CCc1cc2c(cc1C1=CCN(C(=O)C3CNC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CC(=O)NNC(=O)CSc1nnc(Cc2csc(NC(=O)CCl)n2)n1NC(C)=O +CCc1nc(C(N)=O)c(Nc2ccc(N3CCC(N4CCN(C)CC4)CC3)c(C)c2)nc1NC1CCC(O)(CC)CC1 +Cc1ccccc1N1CCc2nc(-c3c(C)cccc3C)nc(N(C)C)c2C1 +CCOCc1nc2c(=O)n(Cc3ccccc3)nc(C)c2c2cc(-c3ccccc3)nn12 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+O=C(CCSc1nc2ccccc2c(=O)[nH]1)NC1CCC(Oc2ccc(Cl)cc2)CC1 +CC(C)COc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1 +O=C(NC1CCCCC1)N1CCc2cc(S(=O)(=O)Nc3ccc(CCCC4CCCC4)cc3F)ccc2C1 +CC1CCc2cc(C(=O)N(C)Cc3cc4ccccc4[nH]3)ccc2N1C(=O)c1ccc(O)cc1O +c1ccc(Nc2nnc(-c3ccc4[nH]cc(-c5cncc(C6CC6)n5)c4c3)o2)cc1 +O=C(NCCCN1CCCC1)C1C(C(=O)NCc2ccc(Br)cc2)C2C=CC1C21CC1 +CC1(CC(=O)O)c2ccc(F)cc2-c2nc(O)c(O)nc21 +Cc1nc2c3c(c(C(=O)N(C)C)cn2c1C)CCC(c1cccs1)O3 +NC(=O)c1cc(COP(N)(=O)N(CCCl)CCCl)ccc1[N+](=O)[O-] +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(Cn4ccnc4)cc3)ncc2F)c1 +Cc1cc(S(=O)(=O)NC(=O)Nc2ncc(Br)s2)sc1CO +O=C(Nc1ccccc1)N1CCN(Cc2ccc3ccccc3n2)CC1 +O=c1nc(OCC2COCCO2)cc2n1CCc1cc(NC3CCCCC3)ccc1-2 +CCOc1ccc2c(c1)CCN=C2c1ccc(S(N)(=O)=O)cc1 +NC(=O)c1cccc2c(NCc3cccc4ccccc34)ncnc12 +COc1ccc(-c2nc(CCOc3ccc4c(c3)CCC4CC(=O)O)c(C)s2)cc1 +COc1cc(Cl)ccc1-c1cccc2cc(S(=O)(=O)Nc3ncco3)ccc12 +CC=Cc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(CCC)c2)c1 +O=C1N(c2ccc(F)cc2)CCc2nc(COc3ccccc3)c(Cl)n21 +COc1cc(-c2cc(F)cc(Cl)c2)c(Cl)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +O=c1[nH]cnc2c(CN(CCO)CCCO)c[nH]c12 +CC(C)CC(Cc1c[nH]c2ccccc12)(NC(=O)OCc1cc2ccccc2o1)C(=O)NC(C)c1ccccc1 +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CC(=O)O)C(=O)O)cc1 +COc1cccc2nc3c(cc12)CC1(O)C2Cc4ccc(O)cc4C1(CCN2C)C3 +COc1ccccc1N1C(=O)C(=Cc2ccc(O)c(Br)c2)OC1=S +CCCCCCN1C(=O)C(Cc2ccc(-c3cc(OC)c(OC)c(OC)c3)cc2)N(C)C(=O)C1C +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3)CC2)cc1 +O=Cc1ccn(-c2cc3c(cc2[N+](=O)[O-])nc(O)c2nc(C(=O)O)nn23)c1 +CC(O)(CNc1nc(N)c2ncn(C3OC(CO)C(O)C3O)c2n1)c1ccccc1 +CNC(=NC#N)N1CCC(CCN2C3CCC2CC(n2c(C)nc4ccccc42)C3)(c2ccccc2)CC1 +COc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)ccc1-c1coc2ccccc12 +Cc1cc(C)c(Nc2nc(N)nc(NC3CCN(Cc4ccccc4)CC3)n2)c(C)c1 +COc1ccc2oc3nc4ccccc4c-3c(N3CCOCC3)c2c1 +CCC(Oc1cccc(CN(CCCOc2ccccc2)c2nc3cc(F)ccc3o2)c1)C(=O)O +O=C(Cc1ccc(Cl)cc1)NC(=Cc1ccc(Oc2ccccc2Br)cc1)C(=O)O +CCCCc1ccc(-c2ccc3c4c([nH]c3c2)-c2ccc(C(=O)O)cc2S(=O)(=O)C4)cc1 +CCCCCC=CCC=CCC=CCC=CCCCC(=O)NCC(F)(F)F 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+Cc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1N(C)c1ncnc2cnc(NC3CCOC3)nc12 +COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(Cl)c2)c1 +N#Cc1ccc(OCCN2CCN(CC(=O)Nc3nccs3)CC2)cc1 +OCCn1cc(-c2cc(F)c3ncc(Cc4ccc5ncccc5c4)n3c2)cn1 +CCc1c(O)cccc1C(=O)NC(Cc1ccccc1)C(O)C(=O)N1CSC(C)(C)C1C(=O)NCc1ccccc1C +COc1ccccc1-c1cccc(-c2c(O)nc3cc(Cl)c(C#N)cc3c2O)c1 +CC1(N2CCC(N(c3ccccc3)c3ccccc3)CC2)CCN(C(=O)C2CCCCC2)CC1 +Cc1ccc(NC(=O)c2cc3cc(C)ccc3oc2=O)cc1 +CC(C)(C)OC(=O)N1CCC(C2CCN(c3ccnc(C#N)n3)CC2)CC1 +Cc1nc2cc(CN(c3ncc4ccccc4c3C)S(=O)(=O)c3ccc(C(=O)O)cc3)ccc2s1 +CC(C)(C)NC(=O)NC(C(=O)N1CC2C(C1C(=O)NC(CC1CCC1)C(=O)C(N)=O)C2(F)F)C(C)(C)C +Cc1cc(-c2nc3cnc(OCC4CC4)cc3n2C(C)c2cccnc2)cn(C)c1=O +C=CCN1CCc2cc(O)cc3c2C1Cc1ccc(O)c(O)c1-3 +CSc1sc(C(=N)N)cc1-c1nc(-c2cccs2)cs1 +CC1COCCN1c1nc(-c2cnc(N)nc2)c2c(n1)N(C1CN(S(=O)(=O)C3CNC3)C1)CC2 +CC(C)COC(=O)CNC(=O)C(Cc1ccccc1)CN1CCC(C)(c2cccc(O)c2)C(C)C1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c2c(n1CC(=O)O)CCNC2=O +Cn1cncc1C(OCc1c(-c2cc(Cl)cc(Cl)c2)cc(C#N)n(C)c1=O)c1ccc(C#N)cc1 +NCCOc1c(-c2ccc(N3CCOCC3)c(Br)c2)[nH]c(=O)c2cc(F)ccc12 +NS(=O)(=O)c1ccc(NC(=O)Nc2ccc3ccccc3c2)cc1 +CC#CC1CN(S(=O)(=O)c2ccc(N)nc2)CCN1c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +COC(=O)C1(C)Nc2c(O)cc3c(c2C1=O)C(CCl)CN3C(=O)c1cc2cc(OC)c(OC)c(OC)c2[nH]1 +CCC1(CCCCN2CCN(c3ccc(F)cc3)CC2)C(=O)Nc2ccc(F)cc21 +Cc1cc(N2CC3CC2CN3C)ccc1-c1ccnc2c(-c3ccc(F)c4[nH]ncc34)c(-c3ccncc3)nn12 +CCC(=O)N(c1ccccc1)C1(COC)CCN(CCn2cccn2)CC1 +C#CCN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +O=C(Cc1ccc(NC(=O)c2cscn2)cn1)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(=O)C1OC(Oc2ccc(C=C(C)C(=O)NC3C(O)C(O)C4OCOC4C3O)cc2O)C(O)C1O +Cc1cc(C)c(-c2nc3cc(OC4COC4)ncc3[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +Cc1ccccc1C(=O)c1ccccc1NC(Cc1ccc(OCCN(C)c2nc3ccccc3o2)cc1)C(=O)O +Cc1ccc2nc(-c3ccc(OCCCN4CCN(c5cccc(Cl)c5Cl)CC4)cc3)cn2c1 +CNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(C4CCC(=O)CC4)c3n2)cc1 +CC(C)CC[n+]1ccccc1C=Cc1ccc(N(C)C)cc1 +Brc1cnc(NCc2ccco2)nc1Nc1cc(C2CC2)n[nH]1 +CCN(CC)CCNc1nc2cc(Nc3ccnc4cc(Cl)ccc34)ccc2[nH]1 +O=C(CCCCN1CCOCC1)Nc1ccc(-c2cccnc2)cc1 +CC1(C)Cc2c(CN3CCC4(CC3)CCN(C(=O)c3ccncc3)CC4)cccc2O1 +CN1C(=O)C2(CC(C)(C)Oc3ccc(-c4cc(Cl)ccc4F)cc32)N=C1N +CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCN(Cc3cccnc3)C2=O)CC1 +O=C1NC(=O)c2c1c(-c1ccccc1)cc1[nH]c3cc(O)ccc3c21 +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)c2cccc(O)c2)CCC3(O)C1C5 +CC(Nc1nccc(N2C(=O)OCC2(C)c2ccccc2)n1)c1ccccc1 +Cc1ccc(-c2nnc(C3CC(F)(F)C3)o2)cc1NC(=O)c1cnc2ccccn12 +CC(C)n1nc(-c2ccc3ccncc3c2)c2c(N)ncnc21 +O=C(CN1CCC(N2C(=O)OCc3cc(Cl)ccc32)CC1)Nc1ccc2ncccc2c1 +COC(=O)c1cc(=O)n(-c2ccc(F)cc2)c(=Nc2ccc(F)cc2)s1 +CC(CCc1cc(-c2ccccc2)no1)(C(=O)NO)S(C)(=O)=O +CN(CCN1CCCCC1)C(=O)N1CCC(C#N)(c2ccccc2)CC1 +C#CCN(Cc1cc2c(O)nc(C)nc2cc1Br)c1ccc(C(=O)NCc2cccnc2)cc1 +N=C(N)c1cccc(C(=O)N2Cc3ccccc3CC2C(=O)Nc2ccc(-c3ccccc3S(N)(=O)=O)cc2)c1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)Nc2nnc(-c3cc(OC)cc(OC)c3)o2)cc1 +CCCCSc1nc2c(c(=O)n1CCc1ccccc1)C1(CCCC1)Cc1ccccc1-2 +CN(C)C(=O)Cn1c(N)c(C#N)c2cc(Oc3ccc(NC(=O)CN)cc3)ccc21 +CCOc1nc(NCCc2ccncc2)ncc1-c1nnc(C2CC2)o1 +COC1Oc2ccc(F)cc2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +COc1cccc(-c2noc(C3CN4CCC3CC4)n2)c1 +CN(C)CC1CCN(c2nc(-c3cc(Cl)ccc3OC(F)F)c(NC(=O)c3cnn4cccnc34)s2)CC1 +C=CC(=O)Nc1cc(Nc2nccc(-c3cn(C)c4ccccc34)n2)c(OC)cc1N(C)CCN(C)C +CC(C)Cc1c(O)cc(O)c2c1OC(c1ccc(O)cc1)CC2=O +CN(CCN1CCCC1)C(=O)Cc1cccc([N+](=O)[O-])c1 +COc1cc(OCc2nc(-c3ccccc3)sc2C)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CCCCCCOc1c(OC)cc(C(=O)OCCCC[N+](CC)(CC)CC)cc1OC +CCCN(CC1CC1)c1cc([S+](C)[O-])nc2c(-c3ccc(Cl)cc3Cl)c(C)nn12 +C[N+](C)(CCCCNC(=O)c1ccc(Cl)cc1)CCNC(=O)c1nc(Cl)c(N)nc1N +O=C1NCC(=O)N(Cc2ccc(F)cc2)C1Cc1c[nH]c2ccccc12 +Nc1ncnc2c(CN3CC(O)C(C4CC4)C3)c[nH]c12 +O=C(NC1CCOCC1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COCCOc1cc2ncnc(Nc3ccc(NC(=O)C45CC6CC(CC(C6)C4)C5)cc3C)c2cc1OCCOC +COc1cc(N)c(Cl)cc1C(=O)NC1CCCN(Cc2ccccc2)C1 +O=C1NC(=O)C2(CCCN2c2ccc(Oc3ccc(Br)cc3)nc2)C(=O)N1 +CS(=O)(=O)NCCNc1nonc1C(=NO)Nc1ccc(F)c(C(F)(F)F)c1 +CC1(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4)nc32)CCN(C2CCNC2=O)C1 +N#Cc1cccn1CCC(NS(=O)(=O)c1cccc2[nH]ccc12)C(=O)N1CCC(C(F)(F)F)CC1 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+COc1cc(C(=O)c2coc(-c3ccccc3)n2)cc(OC)c1OC +COc1cc2c(N)nccc2cc1CC(C(=O)O)N1CCC(NS(=O)(=O)c2cnc(N3CCC(F)C3)s2)C1=O +Cc1cc(N2CCN(CCCCc3nc4c(c(=O)n3N)CCCC4)CC2)nc2ccccc12 +CCN1CCc2c(C#N)c(NCc3ccccc3)nc(N(CC)CC)c2C1 +CCc1cccc(NC(=N)Nc2cc(CC)cc(CC)c2)c1 +COC1CN(CC2CCC(COC3CCC(C(=O)O)CC3)N2C(=O)Cc2ccc3nc(Nc4cc(F)ccc4C)oc3c2F)C1 +Cn1cc(C2=C(c3cccc(OCCN)c3)C(=O)NC2=O)c2ccccc21 +CN(C)CCn1ccc2c(N3CCOCC3)nc(-c3ccc(NC(=O)Nc4ccc(F)cc4)cc3)nc21 +CNC(=O)C1OC(n2cnc3c(NCc4cc(Cl)ccc4OCC(=O)O)ncnc32)C(O)C1N +NC(CO)(CCc1ccc(-c2cn(Cc3ccc(F)cc3)nn2)cc1)COP(=O)(O)O +O=C(O)c1ccc(-c2c(C#Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)cc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NC4CCC(NC(=O)C5(C(F)(F)F)CC5)CC4)nc23)N1 +Cn1cc(C=C2C(=O)NN=C2c2nccs2)c2cc(F)ccc21 +Cc1ncsc1C(=O)N(Cc1cc(=O)[nH]c2ccc(F)cc12)c1cccc(Cl)c1 +O=C(Cc1nc2ccccc2[nH]1)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +CC12CCC3C(CCC4CC(O)CCC43CO)C1(O)CCC2C1=CC(=O)OC1 +Cn1c(-c2cscn2)c(C2CCCC2)c2ccc(C(=O)NC(C)(C)C(=O)Nc3ccc(C=CC(=O)O)cc3)cc21 +COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1-c1ccc(-c3cnn(C(C)C)c3)cc1)CC2 +O=C1C(c2ccc(O)cc2)=C(Br)c2ccc(O)cc21 +COc1ccc(C2=C(c3ccc(OC)c(OC)c3)C(=O)OC2)cc1 +CC(NC(=O)c1ccc(C#Cc2cccc(F)c2)cc1)C(C)(C)O +O=C(NO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1ccccc1Cl +CN(C)CCN1CCSc2cc(N=C(N)c3cccs3)ccc21 +NS(=O)(=O)c1ccc(-n2cc(COC3OC(CO)C(O)C(O)C3O)nn2)cc1 +CN(C(=O)c1ccc(F)cc1)C1CCc2c(CC(=O)O)c3ccccc3n2C1 +CC(C(=O)N1CCOCC1)N1CCC(NS(=O)(=O)c2nc3cc(Cl)ccc3s2)C1=O +Cc1c(Cl)cc2c(c1Cl)CCN2C(=O)Nc1cccnc1 +Nc1ncnc2c1c(-c1ccc3[nH]c(Cc4ccc(Cl)c(Cl)c4)nc3c1)nn2C1CCC(N2CCOCC2)CC1 +COC(C)(C)CNc1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3c(F)cccc3Cl)cc2[nH]1 +Cc1nc(N2CCC(C(=O)NC(C)C)CC2)nc2ccc(NC(=O)COc3ccc(Cl)cc3)cc12 +O=CN(O)CC(CC1CCCC1)C(=O)N1CCCC1C(=O)NC(=O)NCCc1c[nH]cn1 +Cc1cccc(C)c1C(=O)N1CCC(C)(N2CCC(C(=O)c3ccc(Br)cc3)CC2)CC1 +NC(=O)c1cccc2[nH]c(-c3ccc(-c4nnn[nH]4)cc3)nc12 +COc1ccc(C2CC2c2ccc(OC)c(OC)c2OC)cc1 +Cc1nc2ccc(C3CC3)nc2n2c(-c3cc(C(C)(C)O)ccc3F)nnc12 +CN1CCN(c2cccc(CNc3ncc4c(n3)-c3c(c(C(N)=O)nn3C)CC4)c2)CC1 +O=c1ccc2c(OCCCCOc3cccc(C(F)(F)F)c3)c3ccoc3cc2o1 +COc1cccc(-c2cc(F)c(Nc3ncccc3C(=O)O)cc2F)c1 +CCN(CC)C(=O)C1CCC2C3CN(C)C4=CC(=O)C=CC4(C)C3CCC12C +CC(c1ccc2ncc(-c3ccc(F)cc3)cc2c1)n1nnc2ncc(-c3ccncc3)nc21 +CC(C)CN(NC(=O)c1cncc(-c2ccccc2)c1)c1nc(C#N)ncc1Br +CCCCCCC(C)(C)c1cc(O)c2c(c1)OC(C)(C)c1ccc(OC)cc1-2 +O=C(O)c1ccc(N2C(=O)C3ON(c4ccccc4)C(c4ccc(O)cc4)C3C2=O)cc1 +CN1Cc2c(C3=CCN(CC(=O)N4CCC(O)C4)CC3)[nH]c3ncc(F)c(c23)-c2cc(F)ccc21 +c1ccc(-c2cc3c(cn2)ncc2ncn(-c4ccc5nc[nH]c5c4)c23)cc1 +NC1=NCC(Cc2cc(Br)c(N)c(Br)c2)C(N)=N1 +Cn1ccc2ncnc(Oc3ccc(NC(=O)Nc4ccc(N5CCOCC5)c(C(F)(F)F)c4)c(Cl)c3)c21 +NC(Cc1ccccc1)C(=O)N1CCCC1CC(=O)NCc1cc(Cl)ccc1-n1cnnn1 +CN(Cc1ccccc1)C(P(=O)(O)O)P(=O)(O)O +CCc1nc(C(F)(F)F)cnc1NC1CCCC1NC(=O)c1ncccc1-c1ncccn1 +CCc1cc2c(cc1N1CCN(CC3(O)CC(C)OC(C)C3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CCS(=O)(=O)N1CCC2(CC1)COC1(OO2)C2CC3CC(C2)CC1C3 +[H]C([H])([H])c1nc(N(C)c2ccc([Se]C)cc2)c2ccccc2n1 +CCOC(=O)C=Cc1cc(-c2ccc(-c3cccc(O)c3)s2)ccc1O +CC(C)C(CC(=O)NO)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O +O=C(CC(CCCc1ccc(Cl)cc1)C(=O)NC(CC1CCCCC1)C(=O)NCCCCN1CCOCC1)NO +Nc1cnc(-c2ccc(C3CCC3)c(OCCN3C(=O)c4ccccc4C3=O)c2F)cn1 +FC(F)(F)c1cccc(OC(CCN2CCN(c3nsc4ccccc34)CC2)c2ccccc2)c1 +CCCCSc1nc(NC)c2[nH]c(=O)c(=O)n(Cc3ccc(F)cc3)c2n1 +O=C1NCN(c2ccccc2)C12CCN(C1CCOc3ccccc31)CC2 +COc1cc(Cl)cc(OC)c1-c1csc2c(N(CC3CC3)CC3CCOC3)c(OC)nn12 +CC(C)(C(=O)N1CCC(CC(=O)O)CC1)C(NC(=O)c1ccc(C(=N)N)cc1)c1ccc(Cl)cc1 +CCCCCn1c(C)nc2cccc3nc4c(c1c32)Cn1c-4cc2c(c1=O)COC(=O)C2(O)CC +Cc1oc(-c2ccccc2)nc1CCOc1ccc(CC(CNc2ccccn2)Nc2ccccc2C(=O)c2ccccc2)cc1 +O=C1c2cc([N+](=O)[O-])ccc2OCN1CCO[N+](=O)[O-] +CC(C)c1nc(C(=O)NC2CCN(C(C)C)CC2)c2ccccn12 +COc1ccc2c(c1F)C(=O)N(CC1(c3cc4nc(N5CCC(N(C)C)CC5)ccc4o3)NC(=O)NC1=O)C2 +COC1Cc2sc(-c3ccc(C#N)cc3)cc2C2(CCN(Cc3ccccc3)CC2)O1 +CCC1CCCN1Cc1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +Cc1ccc(Nc2nc(Nc3ccccc3)nc(NC(C)C)n2)cc1 +C=CC(=O)N1CCc2ccc(-n3c(=O)ccc4cnc5ccc(-c6cnn(C)c6)cc5c43)cc21 +c1ccc2c(c1)CCC1CN(Cc3ccc4ccccc4c3)CCC21 +Cc1ccc(C(Nc2c(Nc3cccn(C)c3=O)c(=O)c2=O)C2(C)COC2)o1 +CCOC(=O)N1CCC(N2CCC2C(=O)N2CC(Sc3ccccc3OC(F)(F)F)CC2C(=O)NC2(C#N)CC2)CC1 +c1ccc2nc(CCc3cn4c(-c5ccc(-c6nnn[nH]6)nc5)cnc(N5CCOCC5)c4n3)ccc2c1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2cc3cc(F)ccc3[nH]2)n1 +CCCC1CC2OC(=O)c3c(cc(OC)c(OC)c3O)C2O1 +CNC(=O)CCc1cccc(-n2ccc3cnc(Nc4cc(OC)c(OC)c(OC)c4)nc32)c1 +COc1cccc(-c2cnc(Nc3ccc(-c4cnco4)c(OC)c3)o2)c1 +CSc1ccc(C(=O)NC2CCC(NC(C)C)CC2NC(=O)CNC(=O)c2cc(C(F)(F)F)ccc2N)cc1 +O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)N1CCN(C2CCC(O)CC2)C(=O)C1 +CC(NC(=O)c1ccc(-c2nc(C3=CCOCC3)cnc2N)cc1F)c1cc(F)cc(S(C)(=O)=O)c1 +COCCCc1ccc(Cl)c(CN(C(=O)C2=C(c3ccc(OCCOc4c(Cl)cc(C)cc4Cl)cc3)CCNC2)C2CC2)c1 +N#Cc1ccc(C(O)(c2ccc(C(F)(F)F)cc2)c2cccnc2)c(F)c1 +CNC(=O)c1cccc(OCCCCN2CCN(c3cccc4sccc34)CC2)c1 +CCOCCN1CCN(CCCNC(=NC#N)c2ccccn2)CC1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3cc4cc[nH]c4cn3)c2)c2cncnc21 +C=C(C)C1Cc2c(ccc(C(=O)n3c(C)nc4ccccc43)c2OC)O1 +O=S(=O)(Nc1ccc2nccc(N3CCNCC3)c2c1)c1cccc2c(Cl)cccc12 +Cc1ccccc1Nc1nc(N)nc(Nc2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)n1 +COc1ccc2c(c1)Oc1ncn3nc(C)nc3c1C2c1ccc(Cl)cc1 +Nc1ccccc1Nc1ccc2c(c1)CCc1ccccc1C2=O +CNCC(O)C(c1ccccc1)n1ccc2cc(F)ccc21 +CC(=O)NC1CCC(NC(=O)c2cnc(-n3ccc4cncnc43)cc2NC2CCOCC2)CC1 +COc1cccc(C2CCC(N3CCN(c4cccc5ccccc45)CC3)CC2)c1 +CCCc1cc(Oc2ccc(O)cc2)ccc1OCCCOc1cccc(C2SC(=O)NC2=O)c1 +CC(C)CC(NC(=O)Cc1ccc2c(c1)Nc1ccccc1S2)C(=O)NC(CC(C)C)C(=O)NC1CCOC1O +Cc1cc(N=S(C)(C)=O)cc2ncnc(Nc3ccc(Cl)cc3OC(C)C(=O)NCC(F)F)c12 +CC1(c2ccccc2)CCN(CC2CCc3cccnc3C(O)C2)CC1 +COc1cc(OC)c(Nc2ccc3nnc(-c4ccccc4)n3n2)cc1Cl +CCNC(=O)c1ccc(Oc2cccc(CC(=O)O)c2)c(NS(=O)(=O)c2ccc(C)cc2)c1 +C[n+]1c2n(c(=O)c3ccccc31)CCc1c-2[nH]c2ccccc12 +CCNC(=O)c1ccc(-c2ccc(C(=O)N(C3CC3)C3CCN(C(=O)OC(C)(C)C)CC3)cc2)cc1 +CCc1nc(CN2CC(C(=O)O)C2)ccc1-c1cnc(-c2ccc(CC(C)C)c(C)c2)s1 +C=CCN1CC(C)N(C(c2ccc(C(=O)NC(CC)CC)cc2)c2cccc(OC)c2)CC1C +COC1C(F)CN(C(=O)Cn2nc(C(N)=O)c3ccccc32)C1C(=O)NCC1CC1(Cl)Cl +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCN(C(C)=O)CC4)cc3OC)ncc2C(F)(F)F)c1 +COc1ccc(C(=O)Nc2ncc(-c3ccc(C(=O)O)c4ccccc34)s2)cc1 +COc1ccccc1N1CCC(C(=O)Nc2ccc(OC)c(N3CCN(C)CC3)c2)CC1 +CCN(CC)c1ncc(N(CC)c2ccc(F)cc2)c(NC(Cc2ccc(OC(=O)N3CCCC3)cc2)C(=O)O)n1 +CC1CN(CC(=O)Nc2ccc(-c3cccn4c(=O)cc(N5CCOCC5)nc34)c3sc4ccccc4c23)CC(C)O1 +Cc1nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)cc(N2CCOCC2)n1 +NS(=O)(=O)c1ccc(NC(=S)NC(=O)Nc2ccc(CC(Cl)Cl)cc2)cc1 +O=C(CCN1CC2CC(C1)c1cccc(=O)n1C2)c1ccccc1 +CCn1nc(Nc2cccc(C)c2)c2c1CCN(C(C)=O)C2 +Cc1ccc(Oc2ccc(CN3CCC(O)=C(C(=O)NCC(=O)O)C3=O)cn2)cc1 +CC(C)CC(C=O)NC(=O)C(CCS(=O)(=O)c1ccc2ccccc2c1)CC(C)C +Cn1c(=O)c2[nH]c(-c3ccc(OCC(=O)N4CCN(c5ccc(F)cc5)CC4)cc3)cc2n(C)c1=O +COc1ccc(C2(O)CCN(C(c3ccccc3)c3ccccc3)CC2)cc1 +CN(C)CCN1C(=O)c2c(c3c4ccccc4[nH]c3c3ccccc23)C1=O +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=CC2CCCCC2)[nH]c1=O +Cc1oc(-c2ccccc2)nc1CCOc1cccc(C2CN(C(=O)OCC(C)C)CCC2CC(=O)O)c1 +O=C(C=Cc1ccc(Cl)c(Cl)c1)c1ccnc2ccccc12 +NC(=O)c1cccc2c(Nc3ccc(OCc4ccccn4)c(Cl)c3)ncnc12 +CCNC(=O)N1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc([N+](=O)[O-])c4)c3c2)CC1 +COc1cc(Oc2c(C3CCC3)ccc(-c3cnc4[nH]ccc4n3)c2F)ncn1 +Cn1c(C(=O)NCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c(-c2ccc(F)cc2)c2cccnc2c1=O +COc1cc(C(=O)Nc2cc(C(=O)NC3CCCCC3)ccc2-c2ccc(Cl)cc2)cc(OC)c1OC +CC(=C(C#N)C(=O)Nc1ccccc1)c1cn(CC(=O)O)c2ccccc12 +Cc1cc2c(cc1N1CCC(N3CCOCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +COc1cccc(Cn2cccc(C=CC(=O)NO)c2=O)c1 +O=C(O)C1CCCCC1NCc1cc([N+](=O)[O-])cc2nc(O)c(O)nc12 +CC(C)Oc1ccc(S(=O)(=O)N2CCN(c3cc(F)cc(OCC(=O)O)c3)CC2)cc1 +CC(C)Oc1ccc(Nc2cc(=O)n(Cc3ccccc3)cc2C(O)c2ccc(Cl)cc2)cc1Cl +Cc1cc(=O)n(-c2ccc(Br)cc2F)nc1C(=O)Nc1ccc(Oc2ccnc3[nH]ccc23)cc1 +CSc1ncc(C(=O)N2CCN(C)c3ccccc32)c(Oc2cc(Cl)ccc2Cl)n1 +COC(=O)CCc1nc(C)nn1-c1cc(N2CC(c3nc4ccccc4n3C)C2)nc(C)n1 +CCCCCCC[n+]1c(C=Cc2ccc(N(C)C)c3ccccc23)sc2ccccc21 +CN(C)c1ccc(-c2nc3c(C(N)=O)cccc3[nH]2)cc1 +COc1ccc(C2(C(=O)c3ccc(C(=O)c4ccc(N(C)c5ccc(Cl)cc5)cn4)cc3C(=O)O)CC2)cc1 +CSC(=S)N1CC2(CCCCC2)CSC1=Nc1cccc2nsnc12 +CC(C)c1cccc2c(-c3ccccc3)cc(-c3ccc(-c4ccc(C(=O)O)cc4)[nH]3)nc12 +Cc1nc(CNC(=O)c2cc3cc(Nc4nccc(-c5cn(C)cn5)n4)cc(C)c3[nH]2)cs1 +CN1CCN(Cc2cc3nc(-c4ccc(NC(=O)Nc5ccncc5)cc4)nc(N4CC5CCC(C4)O5)c3s2)CC1 +COc1ccc(OC(CCN2CCN(c3ccc(Cl)cc3)CC2)c2ccccc2)cc1 +COC1C(O)C(O)C(Oc2ccc3cc(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C +O=C(O)CCc1c(C=C2C(=O)Nc3ccc(S(=O)(=O)Cc4ccc(F)cc4)cc32)[nH]c2c1C(=O)CCC2 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)N(C)C1c1ccc(C#N)cc1C1=CCOCC1 +Cc1ccccc1CC(NC(=O)c1cccnc1)C(=O)NCCCCC(CO)N(CC(C)C)S(=O)(=O)c1ccc(N)cc1 +Cn1c(=O)c2cc(C#C[Si](C)(C)C)ccc2n2cnc(C(=O)OC(C)(C)C)c12 +COCCNc1ccnc(NC(=O)c2csc(-c3nncn3C(C)C)n2)c1 +O=C(c1cccnc1Oc1ccc(Nc2ccccn2)cc1)N1CC=CC1 +COc1cc(CN(C)CCc2ccccc2)ccc1OCc1ccccc1 +CC(C)CC(NCCc1ccc(-n2c(N)c(C(=O)c3ccc(F)cc3F)ccc2=O)cc1)C(=O)OC(C)(C)C +Cc1ccc(C(=O)Nc2cc(Cl)ccc2OCC(=O)Nc2ccc(S(N)(=O)=O)cc2C)cc1C +Cc1cccc(-c2nc3ccc(N4CCCC(C(=O)N5CCCC5)C4)nc3[nH]2)c1 +COc1ccc(C(NC(=O)c2cc(F)c3cnc(Nc4ccnn4C)nc3c2)c2cnn(C)c2)cc1F +CC1(COc2ccc(Cl)cn2)CN(C(=O)C2CCN(c3ccc(F)cn3)CC2)CC1c1ccc(Cl)cc1 +CC(C)N1CCN(C(=O)NCc2ccc(Oc3ccccc3)cc2)CC1 +CC(OC1CCn2c(O)nnc2CC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Nc1nc2c(c(=O)[nH]1)NCN2CC(CO)OCP(=O)(O)O +CCn1c2ccccc2c2cc(NC(=O)CCc3ccncc3)ccc21 +CCCCCCCCCCCCCCCNOC(=O)CC1OCC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1 +CCCCCCCCCCCCn1nnc(C(NC(=O)c2c(Cl)cccc2Cl)c2ccccc2)n1 +NCCC1CNC(=O)c2cc(-c3cccc(OC(F)(F)F)c3)c(-c3ccc4c(c3)OCO4)n21 +Cc1c(NS(=O)(=O)c2ccc(CCCC3CCN(C)CC3)cc2)c(CCc2ccccc2)nn1C +CN1CCc2cc(-c3ccc4oc5c(-c6ccccc6)nc(=O)n(CCN6CCC(F)(F)C6)c5c4c3)ccc2C1 +NC1CCC(NC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)C1 +Cc1ccc(CCCCN2CCC(C(O)c3ccccc3)CC2)cc1 +CNC(=O)c1ncncc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +CC(C(=O)NCCCc1ccc(Cl)cc1)c1ccc(NS(C)(=O)=O)c(F)c1 +CCCCc1nc2cccc(C(=O)NC(C)C)c2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C1Nc2ccc(F)cc2C1CCCCN1CCN(c2ccc(Cl)cc2)CC1 +O=C(NCc1ccccc1)C1CNCC1C(=O)NCc1ccccc1 +O=C(NCC1(O)CCCCCC1)c1cc(-c2ccccc2C(=O)O)ccc1Cl +Cc1ccc(Nc2nnc(SCc3ccccc3F)[nH]2)cc1 +N=C(N)c1cccc(Cn2c(C(=O)NCCc3ccc(Cl)c(Cl)c3)cc3c(O)cccc32)c1 +CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3cnc4ccccc4c3)C2=O)c(F)c1 +OCC1OC(n2cc(Cc3ccc(C4CCCC4)cc3)c3ccccc32)C(O)C(O)C1O +CCCN(CC1CC1)c1nc(C)nc(Nc2c(C)cc(C)cc2C)c1SCC +C=C(COC(=O)CCCCC[n+]1ccccc1)COC(=O)NCCCCCCCCCCCCCCCCCC +CC(c1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1)N1CCN(C2CCCCC2)CC1 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4cc5cc(C(N)=O)ccc5n4C)c3)cc2C1 +Cc1c[nH]c2ncnc(N3CCC(C)(C(=O)Nc4cccc(OC(=O)N(C)C)c4)CC3)c12 +CC(C)c1cccc(-c2cccc3nc(NC(=O)C4CC4)nn23)c1 +COc1cc2c(Nc3ccc(Cl)cc3F)ncnc2cc1OCCCN1CCCC1 +CC(C(=O)NO)N(Cc1ccccc1[N+](=O)[O-])S(=O)(=O)c1ccc(Cl)cc1 +C#CCNC(=O)c1ncn2c1Cn1ncnc1-c1cc(F)ccc1-2 +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)NNC(=O)Nc4ccccc4)cccc2-3)cc1 +CCC(CC)c1cc(C)nn2c(-c3sc(N4CCOCC4)nc3Cl)c(C)nc12 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(-c4ccc(C(=O)NC5CC5)s4)nc23)N1 +CCc1ccc(-c2cc(C(F)(F)F)nn2-c2ccc(S(N)(=O)=O)cc2)cc1 +O=C(O)CC1CCC(c2ccc(C(=O)Nc3nnc(C4CCCC4)s3)cc2)CC1 +c1ccc(C(Nc2nnc(-c3c[nH]c4ncccc34)o2)C2CC2)cc1 +O=C(O)c1cccc(-c2ccccc2-c2cc(Cl)ccc2OCc2ccc(Br)cc2F)n1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N4CCC(F)(F)C4)c3F)C2)cc1 +Cn1nccc1C(NC(=O)c1ccc2cnc(NC3CCOCC3)nc2c1)c1ccc(Cl)c(F)c1 +CC(C)n1cc(C(=O)c2cncc(NC(=O)c3cc4occc4[nH]3)c2)c2cncnc21 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NS(C)(=O)=O)c1=O)C(=O)C(F)(F)F +COc1cccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CCNCc3ccccc3)c2=O)c1 +CCn1nnc(C2OC(n3cnc4c(NC5CCCO5)ncnc43)C(O)C2O)n1 +COCC(C)Oc1cc(Oc2ccc(OC)cc2)cc(C(=O)Nc2ccc(C(=O)O)cn2)c1 +CC(C)Oc1ccccc1N1CCN(C2CCC(N3C(=O)c4cccnc4C3=O)CC2)CC1 +O=C(O)c1ccc(CNC(=O)c2cc(F)cnc2Oc2ccc(F)cc2)cc1 +Cn1cc(-c2cnc3ccc(NC(=O)Nc4ccccc4)nc3c2)cn1 +COc1ccccc1N1CCN(CCCCN2CSC(C)(C)C2=O)CC1 +O=C(NO)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(=O)Nc1ccc2ccccc2c1 +O=C(NC1CCCC1)c1noc(-c2ccc(Br)cc2)c1Br +CCN(CCOc1ccc(CC(Nc2ccccc2C(=O)c2ccccc2)C(=O)O)cc1)c1cccc(C)c1 +CCC(CC)[N+](C)(C)Cc1ccc(NC(=O)C2=Cc3cc(-c4ccc(C)cc4)ccc3OCC2)cc1 +c1csc(CN2CCN(c3nc4ccccc4n4cccc34)CC2)c1 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+CN(Cc1ccc(-c2nccnc2NS(=O)(=O)c2ccccc2C(F)(F)F)cc1)c1ccc(F)cc1 +O=S(=O)(NCCCN1CCN(CCCNc2ccnc3cc(Cl)ccc23)CC1)c1cc(Br)c(Br)s1 +Fc1ccc(F)c(COC2C3CCN(CC3)C2C(c2ccccc2)c2ccccc2)c1 +Cn1nc(CC(=O)Nc2ccc3ccccc3c2)c2ccccc2c1=O +O=C(NO)c1cc2n(c1)CCN(C(=O)c1cc3ccccc3s1)C2 +CCCN(C)C1C=C(C(=O)O)CC(N)C1NC(C)=O +O=C(C(O)c1cccc(Cl)c1)N1CCC(Nc2ccc3[nH]ncc3c2)CC1 +O=C(C=Cc1cccc(F)c1)NCCCCNc1c2ccccc2nc2ccccc12 +Cn1c(=O)c2c(cc(-n3cc(-c4ccc(Cl)cc4)nn3)n2C)n(C)c1=O +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3C(F)(F)F)CC2)cc1 +O=C(NC1C2CC3CC(C2)CC1C3)N1CCC2(CC1)CC(CCO)c1cccc(Br)c12 +Cc1cccc(-n2ncc(C)c2-c2cc3cnccc3s2)n1 +CCCCCCCCCCCCN(C)C(=O)Cn1cc(Cc2cnc(=O)n(CC(=O)NC)c2)c(=O)nc1SCc1ccc(F)cc1 +Cc1ccc(N2CCc3cc(O)ccc3C2(C)c2ccc(C=CC(=O)O)cc2)cc1 +CCN1C(C(=O)NC(C=O)CC(C)C)Cc2cc3c(cc2S1(=O)=O)OCCO3 +O=C(Nc1cc(F)c(CC(=O)N2CC(F)CC2COc2ccc(C(=O)O)cc2)cc1Cl)Nc1ccccc1Br +Cc1ccc(C(=O)Nc2ccc(Cl)c(-c3ccccn3)c2)c(C)n1 +OCC1OC(OC2C(CO)OC(Oc3ccc(CCc4ccc(O)cc4O)c(O)c3)C(O)C2O)C(O)C(O)C1O +Cc1ccnc(NC(c2ccc(F)cc2)c2cc(Cl)c3cccnc3c2O)c1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3N(C)S(C)(=O)=O)n1)CCN2 +COc1cc(-c2cccc(F)c2)ccc1-c1ncnc2cc(S(=O)(=O)Nc3ncns3)ccc12 +CNc1nc2cc(-n3cnc4cc(-c5ccc(Cl)cc5)sc4c3=O)ccc2[nH]1 +CC(C)(O)CNC(=O)c1ccncc1NC(=O)c1nc(C2CC2)ccc1Nc1cncnc1 +COc1ccc(-c2nc(-c3cc(C)nc(C)c3)c3n2CC(C)OCC3)cc1OC(F)(F)F +Cc1cc(Nc2nccc(-c3ncn(C)c3C)n2)cc2cc(C(=O)N(C)C)[nH]c12 +CC(C)CS(=O)(=O)Nc1ccncc1-c1ccc(C#N)c2ccccc12 +CCCCCCCCCC=CC=CC(SCCC(=O)O)C(O)c1cccc(-c2nn[nH]n2)c1 +COCCN1CCN(c2ccc(-c3ncc4c(n3)N(CCCN3CCOCC3)CC4)cc2)CC1 +CCNC(=O)Nc1nc2cc(-c3ccc(OCCN(C)C)nc3)c(OCC3CCOC3)nc2s1 +Cc1ccc(C(=O)Nc2ccc3c(c2)C=CS(=O)(=O)O3)cc1 +CCCCCCCCCCOc1ccc2c3cc[n+]4nc(CC)c(CC)cc4c3n(C(=O)OC(C)(C)C)c2c1 +Cc1ccc(S(=O)(=O)NC2CNCC(C(=O)NCC(c3ccccc3)c3ccccc3)C2)cc1 +O=C(Cn1nnc(-c2ccncc2)c1-c1ccccc1)Nc1ccc(-c2ccccc2)cn1 +COc1c(Nc2ncc(Cl)c(NC3C4C=CC(C4)C3C(N)=O)n2)ccc2c1CCC(N1CCOCC1)CC2 +CN(c1ccc(Nc2ncc3c4ccncc4n(C4CCCC4)c3n2)nc1)C1CCCNC1 +Oc1nc2c(Cl)cc3c(c2[nH]1)C1c2ccccc2CCC1NCC3 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+O=C(Nc1ccncc1)C(=O)c1cn(Cc2ccco2)c2ccccc12 +CCn1nc(C#Cc2cc(C(=O)Nc3ccc(CN4CCN(C)CC4)c(C(F)(F)F)c3)ccc2C)c2c(N)ncnc21 +CCN(Cc1ccnc(C)c1)C(=O)Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cc(Cl)ccc2OC(F)F)n1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(Oc3cc(N4CCOCC4)ncn3)c(F)c2)no1 +Cc1cc(Oc2ccccc2NC(=O)Nc2ccc(OC(F)(F)F)cc2)n(-c2ccccc2C(F)(F)F)n1 +O=C(c1ccc(-c2ccc(O)c(Cl)c2)cc1)c1cccc(O)c1 +Cc1cc(CC(C)C(=O)N2CCN(c3ccc(C(F)(F)F)cc3C(N)CC(C)C)CC2)ccc1Cl +Cc1ccc(Oc2ccc(Nc3nccc(N)n3)cc2)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(C)c4ncccc4C)ncc23)ccn1 +CCC(C)N1C(=O)NC2(CSC3=C2C(=O)c2ccccc2C3=O)C1=O +CCCCCCCCC(=O)Oc1ccc2[nH]cc(CCN(C)C)c2c1 +CCCn1c(=O)[nH]c2nc(-c3ccc(S(=O)(=O)O)cc3)[nH]c2c1=O +COc1ccc2c(c1)c1c(n2S(=O)(=O)c2ccc(C)cc2)CCCC1CN(C)C +COc1ccccc1N1CCN(CCCCN2CCc3cc(C#N)ccc3C2=O)CC1 +COc1cc2nc(N3CCN(C(=O)c4ccco4)C4CCCCC43)nc(N)c2cc1OC +COc1ccc(-c2cc3c(C)nc(N)nc3n(C3CCC(OCCO)CC3)c2=O)cn1 +C#CCOC(=O)Nc1ccc(Cl)c(-c2nc3ccccc3o2)c1 +CCCCCCCNC(=O)Oc1cccc(CN(C)CCCOc2ccc3c(=O)cc(-c4ccccc4)oc3c2)c1 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+CC(C)OC(=O)N1CCN(C2c3ccc(Cl)cc3C(C(O)c3cncn3C)=Cc3cccnc32)CC1 +Cc1ccc(C)n2nc(CCc3cn(C)c(-c4ccco4)n3)nc12 +O=C(Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)c(Cl)c1)c1ccccc1F +N=C(N)N1CCC(CC(=O)CN2CCCCC(NS(=O)(=O)c3ccccc3)C2=O)CC1 +COc1c(C(C)C)cc2c(c1O)C1(C(=O)O)CCCC(C)(C)C1CC2 +CCc1cc(-c2c[nH]c3ncc(-c4ccccc4)cc23)ccc1C(=O)O +NC1CCc2ccc(CNS(=O)(=O)CC3CC3)cc2C1Cc1ccccc1 +CCC(C)Oc1ncnc2[nH]cc(C=CC(N)=O)c12 +FC(F)(F)Cc1nnc2ccc(-c3ocnc3-c3ccccc3)cn12 +CCCCCCOc1ccc(NS(=O)(=O)c2ccc3c(c2)CCN(CCc2ccc(C(C)(C)CO)cc2)C3)c(F)c1 +CCOC(=O)C(=O)OC1(C)CCC2CC1OOC2(C)CS(=O)(=O)c1ccccc1 +COc1ccc(C=CC(=O)c2cccc(Nc3ncnc4cc(OC)c(OC)cc34)c2)cc1OC +Cc1ccccc1C1CCCN(Cc2ccc(C(=O)N(CCc3ccccc3Cl)C3CCNC3)cc2)C1 +CC(C)(C)NC(=O)N1CCC(NC(c2ccc(Cl)cc2)c2cccnc2)CC1 +O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)c1 +OC(C(COCc1ccccc1F)OCc1ccc(F)cc1)C(O)C(COCc1ccccc1F)OCc1ccc(F)cc1 +O=C(NC1CCN(CCCCc2ccccc2)CC1)c1cccc2ccccc12 +COc1ccc(C(C)O)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O 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+O=c1c2cc([N+](=O)[O-])ccc2[se]n1CCn1[se]c2ccc([N+](=O)[O-])cc2c1=O +CC1CCCC(Nc2ncnc3c2nnn3Cc2ccccc2)C1 +Oc1ccccc1CNCCCCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2 +Cc1c(NC2CCC(N)CC2)nc2ccnn2c1Nc1ccc(F)c(Cl)c1 +CC(=O)Nc1cc(C(C)(C)C)c(SC2=C(O)OC(CCc3ccccc3)(C(C)C)CC2=O)cc1C +Cc1ccc(C(C)(C)C)c(OCCCCCCN2CC(O)C(O)C(O)C2CO)c1 +CCOC1CCC(CS)(C(=O)NC(Cc2ccc(OC)cc2)C(=O)Nc2ccccc2)CC1 +O=c1[nH]nc(Cc2cccc(NS(=O)(=O)c3cccs3)c2)c2c1CCCC2 +O=C(O)C(Oc1ccc(-c2ccc(-c3c(Cc4ccc(O)cc4O)sc4ccccc34)cc2)cc1)c1ccccc1 +CC(C)N1CCC(n2cnc(-c3ccc(F)cc3)c2-c2ccnc(N)n2)CC1 +CNCCN(C)c1cc(F)cc(CCc2cc(C)cc(N)n2)c1 +NS(=O)(=O)OCC1CC(Nc2ncnc(NC3CCc4ccccc43)n2)C(O)C1O +COCCCOc1cc(C(=O)N(CC2CNCC2OC(=O)NCc2ccccc2)C(C)C)ccc1OC +COc1cc2c(Nc3ccc(Br)c(Cl)c3Cl)ncnc2cc1OCC1CN2CCCCC2CO1 +COc1cccc(-c2nc3c(C(=O)Nc4cnccc4C)ccnc3[nH]2)c1 +Cc1ccccc1C(Oc1cc(OCc2ccc3ncoc3c2)ccc1C#N)C(=O)O +CC(Cc1ccc(F)c(F)c1)C(=O)NC1N=C(c2ccccc2)c2ccccc2N(C)C1=O +O=C(O)CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NN1CCC2(CCCCC2)C1 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+O=C(OC1(C2COCC(CC3CC3)N2S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC2(CCN2)CC1 +COc1cc(OC)c2cc(C(=O)c3cnn(-c4ccc5[nH]c(C)nc5c4)c3N)[nH]c2c1 +Cc1n[nH]c2ccc(-c3nnc(NCC(N)Cc4ccccc4C(F)(F)F)s3)cc12 +OCC1C(O)C(O)C(O)CN1CCCCCOCc1ccc(-c2cccnc2)cc1 +C=C1C(O)CC(=CC=CCC(C)(C)CC(C)CCCC(C)(C)O)CC1O +COc1cc(CCNCc2ccc(N3CCN(C)CC3)cc2)c(Cl)cc1NC(=O)Nc1cnc(C#N)cn1 +O=C(Nc1cccc(Nc2ncccc2-c2ncnc3[nH]cnc23)c1)C1CC1 +COc1ccc(-c2nc3cc(-c4csc(C(=O)O)c4)cnc3[nH]2)cc1 +CCCN(CC)C(=O)C(NC(=O)c1ccc(NC(=O)c2ccccc2-c2ccc(C(F)(F)F)cc2)nc1)c1ccccc1 +COc1ncc(-c2cc3c(C)nc(N)cc3n(C3CCCC3)c2=O)cn1 +N=C1NC(c2cccc(-c3cncc(Cl)c3)c2)(C2CC2)C(=O)N1C1CCOCC1 +COCC(NC(=O)Nc1cc2[nH]nc(N)c2cn1)c1ccccc1 +O=C(CC1CCc2ccccc2N1S(=O)(=O)c1ccc(Cl)c(Cl)c1)Nc1ccc(N2CCC(N3CCCCC3)CC2)cc1 +CCOc1ccc(Cl)cc1OCC1CN(Cc2ccc(Cl)cc2)CCO1 +N#Cc1c(-c2ccccc2C(=O)O)cc(-c2ccccc2O)nc1N +c1cc(-c2nn(C3CCCNC3)cc2-c2ccc3c(c2)Cc2c[nH]nc2-3)ccn1 +COc1cc(CCC(=O)NCCCCCC(=O)NNc2c3c(nc4ccccc24)CCCC3)cc(OC)c1OC +Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2c(Cl)cccc2Cl)cc2[nH]c(C3CCCO3)nc12 +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(Cl)cc3Cl)ncnc21 +O=Cc1cn(Cc2cccc(C(F)(F)F)c2)c2ccccc12 +Cc1noc(-c2ccc(OCc3c(-c4ccccc4)noc3C)nc2)n1 +Cc1cncc(N2CCC(CC#N)(n3cc(C(N)=O)c(Nc4ccc(F)cc4)n3)CC2)c1 +O=c1c(-c2cccc(CO)c2)cccn1C(CN1CCC(O)C1)c1ccccc1 +COc1cc2c(cc1OC)-c1c(-c3cocn3)ncn1CC2 +O=C(NC(c1ccc(Cl)c(Cl)c1)C1CCN(Cc2ccc(C(F)(F)F)cc2)CC1)c1ccc2cnccc2c1 +COc1n[nH]c2cc(OCCNCC(O)c3cccc(NS(C)(=O)=O)c3)ccc12 +Cc1ccc(CNC(=O)CC2c3ccccc3N=C(N3CCN(CCN(C)C)CC3)N2c2ccc(-c3ccccc3)cc2)cc1 +Cn1cc(-c2ccc3nc(NC(=O)c4cnn(C)c4Cl)cn3n2)c(-c2ccc(F)cc2)n1 +Cc1nnc2c(NC3CCN(S(=O)(=O)CCCN(C)C)CC3)cc(N(C)Cc3ccccc3)nn12 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3cccc(F)c3)cc2)C1COC(C)=O +Cc1nc(NC(C)c2cccc(OCCCN(C)C)c2)cc(-c2ccc3ncsc3c2)n1 +Nc1cnc(-c2ccc(C3CCC3)c(Oc3nccc(C(F)(F)F)n3)c2F)cn1 +Oc1ccc2c(c1)OC(c1ccc(OCCN3CCCCC3)cc1)C1=C2CCOc2ccccc21 +CC(=O)N(Cc1ccc(C(=O)Nc2cc(-c3cccs3)ccc2N)cc1)Cc1cn(C)nn1 +COc1cccc(C2c3ccc4cccnc4c3Oc3nc4c(c(N)c32)CCCC4)c1 +O=C1Nc2cc(NC(=O)c3c[nH]cc(-c4ccccc4F)c3=O)ccc2C1=Cc1ccc[nH]1 +Brc1ccc(C2=NN(c3nc(-c4ccc(Br)cc4)cs3)C(c3ccc4c(c3)OCO4)C2)cc1 +COc1cc2c(cc1OC)CC(CC1CCN(CCCNc3c4c(nc5cc(Cl)ccc35)CCCC4)CC1)C2 +Clc1ccc(OCCc2ccccc2)c(CCN2CCN(c3ncccn3)CC2)c1 +c1ccc(C(OCCN2CCN(CCCc3ccco3)CC2)c2ccccc2)cc1 +CCCn1c(=O)c2nc(-c3ccc(OCc4nc(-c5ccccc5C(F)(F)F)no4)cc3)[nH]c2n(CCC)c1=O +CN(C)CCN=C(S)Nc1ccc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +COc1cc(C(=O)N(C)C)cc(NC(=O)C2CCC(=O)N2C2CCN(Cc3ccc(Cl)c(C)c3)CC2)n1 +O=C(O)CCCN1C2=C(C(c3ccc(Br)cc3)Oc3ccccc32)C(c2ccc(Br)cc2)n2ncnc21 +CC(C)CC(NC(=O)CCOc1ccc2ccccc2c1)C(=O)NC1CC(=O)OC1O +NC(=O)C(CC1CC1)NC(=O)c1ccc(C(F)(F)F)c(OCC2CC2)n1 +Cc1ccc(C)n2nc(CCc3nc(-c4ccsc4)nn3C)nc12 +COc1cc(C=NNC(=O)C(OC)c2ccc3c(c2)OCCO3)ccc1C(F)(F)F +CC(C)CC(N)CCN(C(=O)C1CC1c1ccccc1)c1ccc(-c2ccccc2)cc1 +Cc1ccc(NC(=O)CC(C)C)cc1-c1ccc(C(=O)NCC2CC2)cc1 +COc1ccccc1-c1noc(-c2ccc(N3CCOCC3)c(C(F)(F)F)c2)n1 +O=c1cc(-c2ccccc2)nc(NC2CCCCC2)[nH]1 +CS(=O)(=O)c1cccc(Oc2cccc(-c3c(-c4ccccc4)nc4c(C(F)(F)F)cccn34)c2)c1 +COc1ccc(CN(C)C(=O)C2(c3ccc(Cl)c(Cl)c3)CC2CN2CCC(NC(C)=O)(c3ccccc3)CC2)cc1 +CCCCCn1cc(C(=O)NC2CCCCCC2)c(=O)c2cnn(C)c21 +Nc1nc(N)c2c(Sc3ccc(N4CCOCC4)cc3)cccc2n1 +CNC(=O)c1ccccc1Nc1nc(Nc2cc(OC)c(OC)c(OC)c2)nnc1Cl +O=C(NCC1NCCc2ccccc21)N1CCC(c2nc(-c3ccc4ccccc4n3)no2)CC1 +CC(Nc1cccc(Cl)c1)c1cc(C(=O)NCCN(C)C)cn2c(=O)cc(N3CCOCC3)nc12 +CN1CCc2ccc(NC(=O)c3cccc(CNC(=O)c4nnn(-c5nonc5N)c4-c4ccccc4)c3)cc2C1 +CC(C)Cc1ccc(C(C)c2nc3ccccc3n2Cc2ccccc2C(F)(F)F)cc1 +CN(C)C1CCN(c2cc(Nc3cc(C4CC4)[nH]n3)nc(-c3cccc(C#N)c3)n2)C1 +CN1C(=O)NC(=O)C12Cc1ccc(NC(=O)CN(Cc3ccccc3)C(=O)C(C)(C)C)cc1C2 +O=C(c1ccccc1)N1Cc2c(-c3noc(C4CC4)n3)ncn2-c2ccccc21 +COCC1OC(=O)c2coc3c2C1(C)C1=C(C3=O)C2CC(Br)C(=O)C2(C)CC1OC(C)=O +FC(F)(F)c1cccc(NC(=S)N2CCCC2c2ccncc2)c1 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OC2C3CC4CC(C3)CC2C4)cc1F +Cc1cc2c(N3CCN(CCc4ccc5c(c4)NC(=O)CO5)CC3)cccc2[nH]1 +CCOCCC1(Oc2ccc(Oc3ccc(-c4nnco4)cc3)cc2)C(=O)NC(=O)C(N)C1=O +Cc1ccc(-c2cc(NCC(O)CO)c3ccccc3n2)cc1Cl +Cc1ccccc1CC(NCP(=O)(O)O)C(=O)NC(Cc1ccc(-c2ccccc2)cc1)C(=O)O +NS(=O)(=O)c1cc2c(s1)C(O)CCS2(=O)=O +O=C(Cc1cnc[nH]1)NC(CCCc1ccccc1)C(=O)Nc1ccc(Oc2ccccc2)cc1 +COCCCCn1c(=O)cc(Nc2ccc(C)c(Br)c2)[nH]c1=O +N#Cc1ccc2[nH]cc(CCCCN3CCN(c4ccc5sc(C(N)=O)cc5c4)CC3)c2c1 +CCCCCCC(C(=O)N1CC(Oc2cccnc2)CC1C(=O)O)n1cnc(NC(=O)c2ccccc2S(=O)(=O)O)c1 +O=C1c2sc(COc3ccccc3)nc2CCN1c1ccc(F)cn1 +CC(=O)c1cnc2ccc(-c3cc(F)c(O)c(Cl)c3)cc2c1Nc1ccc(N2CCC(N(C)C)C2)nc1 +Nc1ncc(-c2ccc(CN3CCOCC3)s2)cc1C(=O)Nc1ccnc2ccoc12 +Cc1c(NC(=O)c2ccc(N(C)C)cc2)cccc1-c1cn(C)c(=O)c(Nc2ccc(C(=O)N3CCOCC3)cc2)n1 +CCCOc1ccc(NC(N)=S)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 +O=C(c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2)c1Cn1cncn1)N1CCN(c2ncccn2)CC1 +COc1ccc(-n2nc(C#N)c3c2C(=O)N(c2ccc(C4(CN5CCOCC5)CC4)cc2)CC3)cc1 +N#Cc1ccccc1OCC(O)CNCCNC(=O)Nc1ccc(Br)nc1 +CCCS(=O)(=O)Nc1ccc(F)c(Nc2ccc3nccnc3c2)c1Cl +COc1cc(N(CC2CC2)c2cccc3c(C(F)(F)F)cccc23)cnc1C(=O)C1CC1C(=O)O +CCNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)c3cnn(CCN(C)C)c3n2)cc1 +CC1CC(C)CN(C(=O)c2cc(Br)ccc2NC(=O)CCC(=O)N(C)C)C1 +CC(C(=O)O)c1ccc2c(c1)OCC(Cc1ccccc1)C2O +CC(C)(C)c1ccc(CNC(=O)NCc2ccc(NS(C)(=O)=O)c([N+](=O)[O-])c2)cc1 +O=C(CC(c1ccccc1)c1ccccc1)N1CCN(C(c2ccccc2)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)CC1 +COc1ccc(Cl)cc1N1CCN(C2CN3CCC2CC3)C1=O +O=C(Nc1ccccc1)N1CCC(Cc2cnc3ccccc3c2)CC1 +Cc1nc(N)nc(-c2cc(CN3CCN(S(C)(=O)=O)CC3)cnc2Nc2ccc3scnc3c2)n1 +O=C1CC(CN2CCC(C(=O)c3ccc(F)cc3)CC2)Cc2[nH]ncc21 +CN(C)CCc1cccc2c1ccn2S(=O)(=O)c1ccccc1 +CC(C)c1onc(-c2ccc(F)cc2)c1-c1ccncc1 +CCCC1(CCc2ccccc2)CC(=O)C(C(c2cccc(NS(=O)(=O)c3cn(C)cn3)c2)C(C)(C)C)=C(O)O1 +CCCN(Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1)c1nc(C(F)(F)F)c(C(=O)O)s1 +Cc1nnc2n1-c1ccccc1C(c1ccccc1)=NC2NC(=O)Nc1ccc(Cl)cc1 +CCCCCCCN(CCCCCSc1nc(-c2ccc(C)cc2)c(-c2ccc(C)cc2)[nH]1)C(=O)Nc1ccc(F)cc1F +COc1ccccc1-c1ccc(CC(NC(=O)C2(S(=O)(=O)c3ccc(C)cc3)CCCCC2)C(=O)O)cc1 +CC(=O)N1CCCC1Cn1nc2c(c1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)ccc1C)C2=O +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(C(=O)CC(F)(F)F)CC1 +NC(CC(=O)NC(c1ccccc1)c1ccccc1)C(=O)N1Cc2ccccc2C1 +CNC(=O)c1cc(OC)cc(N(CCCN2CCCC2)c2ccc3ncc(-c4cnn(CCO)c4)nc3c2)c1 +CCOC(=O)C1Nc2cc(Cl)cc(Cl)c2S(=O)(=O)N1Cc1cccc([N+](=O)[O-])c1 +Oc1c2c(nc3ccccc13)C(c1ccc3c(c1)OCO3)N(c1ncccn1)C2 +Cn1ccc(CNC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)n1 +Clc1ccc(Nc2nccc(-c3cnn4ncccc34)n2)cc1Cl +CC(NP(=O)(OCC1C=CC(n2cnc3c(N)ncnc32)C1)Oc1ccccc1)C(=O)OCC(C)(C)C +CC(=O)Nc1cc(-c2cccc(C)c2)nc(-n2nc(C)cc2C)n1 +CN(Cc1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)CC1CCCN1C +COc1cc(-c2cccn(Cc3ccc(CCC(=O)O)cc3)c2=O)ccc1NC(=O)Nc1c(C)cccc1C +COc1ccc(S(=O)(=O)N2CCN(C(=O)OCc3ccccc3)CCC2C(=O)NO)cc1 +CCN1c2ncccc2C(=O)N(C)c2ccc(-c3ccco3)nc21 +CCC(=C(c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccc(O)cc1 +O=P([O-])(O)C(O)(C[n+]1cccc(Cc2ccccc2)c1)P(=O)(O)O +Cc1c(CO)nc(O)c2c1ccc1nc(Nc3c(Cl)cccc3Cl)n(C)c12 +Cc1ccc(-c2ncc(C(=O)NCCCN(C)c3ccccc3)nc2-c2ccc(C)cc2)cc1 +CCCC(Cc1cc2cc(-c3ccccc3C)ccc2nc1N)C(=O)NCC1CCCCC1 +O=C(NNc1ccccn1)C12CC3CC(CC(C3)C1)C2 +NS(=O)(=O)c1cc(NC(=O)Nn2ccc3ccccc32)c(Cl)cc1Cl +CC(=O)OC1CC2CCC3C(CCC4(C)C3CC([N+]3(C)CCCCC3)C4OC(C)=O)C2(C)CC1N1CCCCC1 +CN1CCCC(c2nc3ccccc3n2Cc2ccc(F)cc2)C1 +Cc1c(Cc2ccc(S(C)(=O)=O)cc2)c2c(n1CC(=O)O)CCNC2=O +Cc1ncn(-c2ccc3c(c2)CCc2cn(Cc4ccccc4)nc2N3)n1 +O=C(NC(c1ccc(F)cc1)c1ccnc(F)c1)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1 +NC1C2CN(c3ncc(C(=O)Nc4ccc(OC(F)(F)Cl)cc4)cc3-c3cncnc3)CC12 +CCCCc1nn2c(-c3ccccc3)c(C)nc2n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1ccccc1S(=O)(=O)c1c(C(=O)NNCCO)[nH]c2ccc(Cl)cc12 +Cn1c2c(c3cc(S(=O)(=O)c4cccc(F)c4)cc(O)c31)C1CCC(C2)N1 +CC1CN(C(C)CO)S(=O)(=O)c2ccc(C#Cc3cccnc3)cc2OC1CN(C)C(=S)NC1CCCCC1 +CN(C)CCCOc1cc(F)c(-c2c(Cl)nc(-n3ccnc3)nc2NCC(F)(F)F)c(F)c1 +CNc1nc(Nc2ccc3c(c2OC)CN(C(C)(C)O)C3=O)ncc1C(F)(F)F +O=C(NC1CCCC1NC(=O)c1ccc2c(c1)N=CC2Cl)c1ccc(-n2ccccc2=O)cc1 +CN1CCCCC(c2ccc(C#Cc3ccc(F)cc3)cn2)C1=O +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccc(-c2ccc(Cl)cc2)o1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccc(OCC4CCC4)cc3)C2)cc1 +CN1CCN(CCCN(C(=O)Nc2ccc(F)c(Cl)c2)C2CCC3(c4cccc(C#N)c4)CC3C2)CC1 +C=CC(=O)N(C)c1cccc(-n2c(-c3nc(-c4cnn(C5CCN(C)CC5)c4)cnc3N)nc3ccccc32)c1 +O=C(NCC1(O)CCCCC1)c1cc(OCC2CC2)c(Cl)cn1 +COC1CCC2(CC1)Cc1ccc(OCC(C)C)cc1C21N=C(N)N(CC(F)(F)F)C1=O +CNC(=O)c1cn(C)c2c1C(C)(C)Cc1cnc(Nc3cccc(OC4CCN(C)CC4)c3)nc1-2 +NC(=O)c1c(-c2ccc(Cl)cc2Cl)csc1NC(=O)Cc1ccccc1 +C=CCNc1nc(N2CCC(NCC(c3ccccc3)(c3ccccc3)c3ccccc3)CC2)nc2c1ncn2CC=C +N=C(N)c1ccc(CNC(=O)CNC(=O)C(CCc2cccc[n+]2[O-])NS(=O)(=O)Cc2ccccc2)cc1 +CCC(=O)Nc1ccc(Sc2nc(Nc3cc(C)[nH]n3)c3ccccc3n2)cc1 +CCNC(=O)c1noc(-c2cc(C(C)C)c(O)cc2O)c1NC(=O)C1CCN(C)CC1 +O=C1c2c(F)cc(C3CC3)cc2OCCN1c1nccc(-c2ccnc3[nH]c(C4=CCNCC4)cc23)c1CO +Cc1csc(NC(=O)NC2C3CC4CC(C3)CC2C4)n1 +O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)C1CCOC1 +CS(=O)(=O)c1ccc(-c2nnc(C=Cc3nnc(-c4ccc(C#N)cc4)o3)n2-c2ccccc2Cl)nc1 +N#CC(c1cccnc1)N1CCN(C(=O)CN(Cc2ccccc2)Cc2ccccc2)CC1 +CC(Nc1cc(-c2c(N)nn3cccnc23)ncn1)c1ccccc1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2ccsc2S(=O)(=O)NC(=O)c2ccccc2)cc1 +O=C(c1ccc(C(F)(F)F)cc1)C(O)c1ccc(C(F)(F)F)cc1 +CC1(C)c2cc(N3CCC(O)CC3)ccc2C(=O)c2c1[nH]c1cc(C#N)ccc21 +C1=CCNc2cc[n+](c3ccccc23)CCCCC[n+]2ccc(c3ccccc32)NC1 +CC1CN(C(C)C)C(=O)c2cccc(NC(=O)c3ccncc3)c2OC1CN(C)Cc1ccccc1Cl +COC(=O)C1=C(c2ccc(-c3ccco3)cc2)CC2CCC1O2 +CC1CC(c2ccncc2NC(=O)c2nc(-c3c(F)cccc3F)ccc2N)CC(N)C1O +COc1cc(C=CC(=O)NC2CCC(NC(=O)C(O)C(N)CCc3ccccc3)CC2)cc(OC)c1OC +COc1cc2c(c3c1c(=O)c1c4ccc(Br)cc4ccc1n3C)C(OC(C)=O)C(OC(C)=O)C(C)(C)O2 +CN(C)C(=O)Cc1nn(-c2ccccc2)c(=O)c2c1c1ccc(Cl)cc1n2CCOCCF +Cc1cc(-c2n[nH]c3ccc(C(=O)NC(CO)c4cccc(Cl)c4)cc23)ccn1 +O=C(NCCCCN1CCN(c2ncccn2)CC1)c1cc2ccccc2cn1 +O=C(NCCC1CCN(Cc2ccccc2)CC1)c1cccc(-c2n[nH]c3ccc(-c4nc[nH]n4)cc23)c1 +O=C(CCc1ccccc1)NC(Cc1ccccc1)C(=O)CCl +CCOc1ccc(N=c2[nH]c(=O)n(CC(C)(C)C(=O)O)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl +FC(F)(F)c1ccc(Nc2nc(N3CCCCCC3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1Cl +CN(C(=O)c1ccccc1-c1ccccc1)C(C)(C)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCCC(O)C1CC(Cc2ccccc2)CCN1CCCNC(=O)Nc1cccc(C(C)=O)c1 +CC(C)n1nc(-c2cc(F)c3cn[nH]c3c2)c2c(N)ncnc21 +O=C(NCCCn1ccnc1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1OCCc3ccccc31)CC2 +Clc1cc(Cl)c2c(c1)oc1c(Cl)c(Cl)c(Cl)cc12 +O=C(O)c1cccc(C2=C(c3cc(Br)ccc3OCc3ccc(F)cc3F)CCC2)c1 +Cc1oc(-c2ccccc2)nc1CCOc1cccc(Cc2nn(-c3ccccc3)nc2C(=O)O)c1 +COc1cnc(C(=O)Nc2cc(C)c(F)c(C3(CF)CC(C(F)(F)F)OC(N)=N3)c2)cn1 +CN(Cc1c[nH]c2nc(N)nc(N)c12)c1cccc2ccccc12 +NC(CC(=O)N1CCN(C(c2ccc(F)cc2)c2ccc(F)cc2)C(=O)C1)C(=O)N1Cc2ccccc2C1 +Cc1ccc(-n2ccnc2)c(NC(=O)c2cnc(-c3ccccc3)s2)c1 +COc1ccc(CCNc2cc(N3CCN(C(=O)c4ccccc4F)CC3)ccc2[N+](=O)[O-])cc1OC +Cn1nc(N)c2cn(C3OC(CO)C(O)C3O)c3ncnc1c23 +O=Cc1cccc(-c2ccc(C3(NCC(=O)Nc4ccc(F)c(Cl)c4)CCN(C4CCCC4)CC3)cc2)c1 +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(n1cc(CCC(=O)OCc3ccccc3)nn1)CC2 +Cc1cc(COc2nc(N)nc3ccn(Cc4ccccn4)c23)no1 +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(OC(=O)Nc3ccccc3)CCc3ccccc32)c1 +CCCn1c(=O)c2[nH]c3cnccc3c2n(CCC)c1=O +Cn1cc2c(nc(NC(=O)Nc3ccc(Cl)cc3)n3nc(-c4ccco4)nc23)n1 +CC(CCc1c[nH]c2ccc(F)cc12)N(CC1CC1)C1COc2c(F)ccc(C(N)=O)c2C1 +COc1cc2c(cc1Nc1ncc(Cl)c(Nc3ccccc3S(=O)(=O)C(C)C)n1)CNCCO2 +CC1Oc2ccc(CN3CCC(c4ccccc4)CC3)cc2NC1=O +CCCn1c(=O)c2[nH]c(-c3cnn(Cc4cccc(F)c4)c3)nc2n(CC)c1=O +Cc1cccnc1C(F)(F)CNc1ccc(C#N)c(CC(=O)NCCONC(=N)N)c1F +Cc1nnc2n1-c1ccc(-c3cncc(C(F)(F)F)c3)cc1CC2 +Cc1ccncc1-c1cc2c[n+]([O-])c(NC(=O)C3CC3F)cc2cn1 +CCC(Nc1ncc(-c2ccccc2)n1C)c1ccc(Cl)cc1 +N=C(N)c1cccc(OC(C(=O)Nc2ccc(-n3ccc(C(F)(F)F)n3)cc2)c2ccccc2)c1 +COc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Sc2ccc(C(C)C)cc2)CC1 +Nc1[nH]cnc2c(C3NC(CSCc4ccccc4)C(O)C3O)cnc1-2 +CC(Nc1ncc(F)c(N2CCOC2=O)n1)c1cc(F)c(Br)cc1F +COc1ccc2nc(COc3cc4c(cc3Cl)OCO4)[nH]c2c1 +CCc1c(C)[nH]c(=O)c(NC)c1Cc1cc(C)cc(C)c1 +CCc1nccc2c1c(Sc1ccc(Cl)c(Cl)c1)c1n2CCC1CC(=O)O +CNC(=O)C(Cc1ccccc1)NC(=O)C(CC(C)C)C(CSCC(=NO)c1ccc(-c2ccccc2)cc1)C(=O)NO +O=C(O)C1CN(Cc2ccc(-c3cc4cc(OCC5CC5)ccc4o3)c(F)c2)C1 +CNc1cc(CSc2ncccc2C(=O)Nc2cc(C)cc(C)c2)ccn1 +CC1COCCN1c1nc(N2CCCC(CO)C2)nc2nc(-c3cccc(C(N)=O)c3)ccc12 +O=C(CN1CCCCC1)NN1c2ccccc2Sc2cc(Cl)ccc21 +CC(C)C(Oc1ccc(CNC(=O)C2CCCN2C(=O)C(N)C2CCCCC2)cc1)C(=O)O +COc1ccc(C2C3=C(CC(C)(C)CC3=O)Nc3nc4c(c(N)c32)CCCC4)cc1 +CC1Cc2cc(CCN3CCN(CCc4ccc5c(c4)CC(C)OC5=O)CC3)ccc2C(=O)O1 +Cc1cc(C)c(S(=O)(=O)NC(CNC(=O)c2cccc3c2cnn3CCCNc2ncc[nH]2)C(=O)O)c(C)c1 +O=S(=O)(c1ccc(OC2CCCC2)c(F)c1)N1CCCC(Cn2ccnc2)C1 +Cn1c(=O)c2c(-c3cc(F)ccc3Br)c(CN)c(O)nc2n(C)c1=O +Cc1c(-c2ccc(F)c(C(F)(F)F)c2)sc2c1c(=O)n(CCCO)c(=O)n2C +CC#CCNc1ccc(S(=O)(=O)N2CCC(S)C2)cc1 +CC(C)(O)CCc1ccc(-c2ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc2)cc1 +CCOC(=O)N1CCN(CCCOc2ccc(-c3cc[nH]c3)cc2)CC1 +Cn1cc(C2=C(c3nn(CCCN4CCCCC4)c4ncccc34)C(=O)NC2=O)c2ccccc21 +COc1cc2[nH]c(C)c(C3CCCCC3)c(=O)c2cc1Cl +CNc1nc(CC(F)(F)F)c(-c2ccnc(Nc3ccc(O)cc3)n2)s1 +CN1Cc2n[nH]c(=O)c3cccc4[nH]c(c2c43)C1 +O=C1c2cc3c(cc2-c2c1c1ccc([N+](=O)[O-])cc1c(=O)n2CCCN1CCCC1)OCO3 +Cc1cccc(C(=O)C2=C(N(C)C)C(=O)NC3(CCCC3)C23CCCC3)c1 +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cnn(CC4CCCCO4)c3)c(C(=O)O)n1)CC2 +COc1ccc2c(c1)CN(C)CC2c1ccc(C)c(F)c1 +O=C(NS(=O)(=O)c1ccc(Cl)cc1)c1ccc(Br)cc1Cl +CCOc1cc(C=NN=C(N)CC(O)c2cccc3ccccc23)ccc1O +COc1cc2c(Oc3ccc(Nc4ccc(C(C)(C)C)cc4)cc3)ccnc2cc1OCC(O)CN1CCOCC1 +CCN(C(C)=O)c1ccc(OC)c2nc(NC(=O)N3CCC(c4cccc(C(F)(F)F)c4)CC3)sc12 +CCC(CN1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)NC(CCN(C)C(C)(C)C)C1=O)c1ccccc1 +CCOC(=O)c1cnn(CC(O)c2ccccc2)c1NC(=O)Nc1cccc(F)c1 +CCN(CC)c1ccc(NC(=O)c2c(-c3c(Cl)cccc3Cl)noc2CCC2CCOCC2)cc1 +Cc1ncc(-c2ccn(C)c(=O)c2)c(OCC2CC2c2ccccn2)n1 +Cn1cc(Cc2cn(CC(=O)N3CCN(Cc4ccccc4)C(=O)C3)c(SCc3ccc(F)cc3)nc2=O)cn1 +CCCc1c(Oc2c(C)n(-c3noc4cc(Cl)ccc34)c3ccc(OC(F)(F)F)cc23)cccc1OC(C)C(=O)O +COc1ccc(CCCOC(=O)C2CCCCN2S(=O)(=O)c2ccccc2)cc1OC +Cc1cn(C2C=CC(COP(=O)(OCC(Cl)(Cl)Cl)OCC(Cl)(Cl)Cl)O2)c(=O)[nH]c1=O +CC(C)N1CCN(C(=O)OC2CCN(c3nnc(N4CCOCC4)s3)CC2)CC1 +O=C(O)CCNCc1cc([N+](=O)[O-])cc2nc(O)c(O)nc12 +CCN(CCCCNC1=CC(=O)C(NCCCCN(CC)Cc2ccccc2OC)=CC1=O)Cc1ccccc1OC +Cc1cccc(Cn2c(C)nnc2C2CCN(c3ccccn3)CC2)c1 +N#Cc1cccc(-c2coc(-c3ccc(Oc4ccc(N5CCCC56C(=O)NC(=O)NC6=O)cn4)cc3)n2)c1 +CCOc1cc2c(Nc3cc(OC)c(Cl)cc3Cl)c(C#N)cnc2cc1OCCCN1CCN(C)CC1 +O=c1ncn(Cc2ccc(F)cc2F)c2ccc(Oc3ncccc3Br)cc12 +CN(C)CC(NC(=O)c1ccc2[nH]nc(-c3nc4ccccc4[nH]3)c2c1)c1ccccc1 +CCc1ccc(Oc2ccc(S(=O)(=O)NCCc3ccccn3)cc2F)c(O)c1 +CC(C)(C)[Si](OCc1cnn(Cc2ccccc2)c(=O)c1)(c1ccccc1)c1ccccc1 +CCN1CN(C)C2(CCN(CCCC(=O)c3ccc(F)cc3)CC2)C1=O +c1ccc(-n2cnc3ccc(OCc4ccc5ccccc5n4)nc32)cc1 +CCCCCS(=O)(=O)NC(=O)CCc1ccccc1Oc1ncc(C(F)(F)F)cc1Cl +COCCCN(C)c1ncc(Cl)c(N2CCC(Oc3ccc(C(C)NC(C)=O)cc3)C2)n1 +O=C(O)COc1ccc(C(=O)CNC(=O)c2sc3c(c2Cc2ccccc2)CNCC3)cc1OCC(=O)O +CC(C)c1cc(Oc2c(Br)cc(NC(=O)C(N)=O)cc2Br)ccc1O +CCNc1nc(N=[N+]=[N-])nc2c1ncn2C1C(O)C(O)C2(C(=O)NC)CC12 +Nc1nc(NC2CCS(=O)(=O)CC2)c2sc(-c3ccc(C(F)(F)F)cc3)cc2n1 +CCn1c(-c2ccccc2-c2cccc(NCC(=O)O)c2)nc(-c2ccccc2)c1-c1ccccc1 +CC(C)Nc1nc2ccc(-c3ccnn3-c3ccc(F)cc3)cc2s1 +COCCn1c(C)c(-c2cnc(C)nc2OCC2CC2c2ccc(C)cn2)ccc1=O +CC(=NO)c1cccc(C(C)(C)NC(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)c1 +COc1cc2c(cc1F)C1(CO2)C(=O)N(Cc2ccc(C(F)(F)F)o2)c2ccccc21 +COc1cc2ncnc(Nc3cccc(Br)c3)c2cc1OCCC(=O)NO +COc1ccc(C)cc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +CCn1c(C)c(-c2ccc(CC(NC(=O)c3c(C)cccc3Cl)C(=O)O)cc2)c(=O)n(CC)c1=O +O=C(CCNCCN1CCCCC1)Nc1ccc(-c2cccc3c(=O)cc(N4CCOCC4)oc23)c2sc3ccccc3c12 +CC1CN(C(=O)c2cn3c4c(cccc24)OCC3C2CCCCC2)CC(C)N1C +NC(CC(=O)N1CCCC1C(=O)NCCCCc1nn[nH]n1)Cc1ccccc1F +N#Cc1ccc(C2=NOC3CCCCCCC23)cc1C(F)(F)F +CC(C)(Oc1ccc(N2CCOCC2)cn1)C(=O)NC1C2CC3CC1CC(CC(N)=O)(C3)C2 +O=c1c2cn[nH]c2c2ccc(-c3cncnc3C3CCCC3)cc2n1CC(F)(F)F +O=c1c2cc(F)ccc2nc(CNc2ccccc2F)n1-c1ccccc1Cl +CC(C)OC(=O)N1CCN(c2ccnc(-n3ccnc3)n2)C(CC(=O)NCc2ccc3c(c2)OCO3)C1 +CC(C)c1cc(-c2ccccc2)nc(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +CCc1c(C#N)c(-c2ccc(-c3ccccc3SC)cc2)c(C(=O)O)n1C +CCCCCCS(=O)(=O)c1ccc(C(=O)CCN2CCNC(=O)C2)c(Cl)c1 +NCCOc1c(C2CCC2)ccc(-c2cnc(N)cn2)c1F +O=C(O)CC(NC(=O)c1cccc(Cl)n1)c1ccc(-c2ccccc2)cc1 +CCCCC(NC(=O)OC1CN(C(=O)c2ccc(-c3ccccc3)cc2)CC1(C)C)C(=O)C(=O)NC(C)c1ccccc1 +N#Cc1ccc(-c2ccc(CC(C#N)NC(=O)C3NC4CC3C3CC43)c(F)c2)s1 +CC(C)(CNC(=O)c1cnc2ccccc2n1)c1ccccn1 +CN1CCC(=CCn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +COc1cc(-c2nn(C3CCC(N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NC(=O)c1cc2ccccc2[nH]1 +COC(=O)CCCC#Cc1ccc(CC(NC(=O)c2ccc(S(N)(=O)=O)cc2)C(=O)O)cc1 +Cc1ccc(S(=O)(=O)C2(C(=O)NC(Cc3ccc(-c4ccccc4)cc3)C(=O)O)CCCCC2)cc1 +CCNC(=O)c1ccc(-c2nnc(C3(c4ccc(Cl)cc4)CCC3)n2C)cc1 +COc1cccc(NCCC2(c3ccc(F)cc3)CCOC(C)(C)C2)c1 +COCC1CCCN1C(=O)c1cn2c(n1)CN(c1cc(-c3ncc(C)cc3C)c(Cl)cn1)CC2 +CCS(=O)(=O)Nc1cccc2c1CCCC2c1c[nH]cn1 +COc1cc(Nc2nc3c(s2)CCCC3c2ccccc2)ccc1-c1nc(C)no1 +CCN(CCCN1CCc2cc(OC)ccc2C1)S(=O)(=O)c1ccc(C)cc1 +O=[N+]([O-])c1ccc(C=Nn2c(CO)nc3ccccc32)s1 +CC(Cc1ccc(OCC(N)=O)cc1)NCC(O)c1cccc(Cl)c1 +COc1ccc2c(c1)CCC1N=C(NCC3CCC(CNS(=O)(=O)c4ccccc4F)CC3)CC21 +Cc1cc(-n2[nH]c3c(cnc4ccccc43)c2=O)c(Cl)s1 +CC(C)(C)NC1CCC(n2cc(C(N)=O)c(Nc3ccc(C(F)(F)F)cc3)n2)C(C#N)C1 +CC(CCCc1ccccc1)NC(=O)Nc1ccc2ncc(-c3cnn(C)c3)nc2n1 +CC=CC(C(=O)NCCCC)N1C(=O)c2cc(NC(C)=O)ccc2NC(=O)C1C +O=c1[nH]c2cc([N+](=O)[O-])ccc2oc1=O +NC(=O)C(CCC(=O)O)NC(=O)C(CC(=O)O)NC(=O)CCc1cc(-c2ccc(-c3cccc(Cl)c3)cc2)no1 +CC1SCc2ncnc(N3CCN(C(=O)C(Cc4ccc(Cl)c(F)c4)CC4(N)CC4)CC3)c21 +Cc1ncccc1NC(=O)c1cccc(-n2cc(NC(=O)Nc3ccccc3Cl)cn2)c1 +O=C(NC1CCN(Cc2ccc(OC3CCNCC3)c(Br)c2)CC1)c1cc2cc([N+](=O)[O-])ccc2s1 +CCCCCC#CCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +CC1CC(N)CC(c2ccncc2NC(=O)c2cccc(-c3c(F)cccc3F)n2)C1 +c1cc(-c2csc3ncnc(N4CCC(COCCN5CCCC5)CC4)c23)ccn1 +CC(C)(C)OC(=O)N1CCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)C1 +COc1ccc(Oc2ccc3cc4n(c(=O)c3c2)C(=S)NC4=O)cc1 +NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(F)cc3)c2)c1 +N#CC(=Cc1cn(CC(=O)O)c2ccccc12)C(=O)N1CCCc2ccccc21 +CC(CO)n1cc(C(=O)c2cc(NC(=O)Cc3cccc(C(F)(F)F)c3)ccn2)c2cnccc21 +Cc1sc2nc(CSC(C)C(=O)Nc3ccc(Cl)cn3)nc(O)c2c1C +CC(C)c1ccc(Cn2cc(C=NNC(=O)c3ccc(O)c(Cl)c3)c3ccccc32)cc1 +COc1cn(-c2ccc3c(c2F)C2(CCC2)C(=O)N3C)nc(-c2ccnn2-c2ccccc2)c1=O +CN1C(=O)CC(c2ccccc2F)C1C(O)c1ccc(-c2ccccc2)s1 +CC1(C)CC2CC(C)(CN2C(=O)c2ccc(-c3csc4ccccc34)cc2Cl)C1 +O=C1Nc2cc(F)ccc2C1CCCCN1CCN(c2ccccn2)CC1 +CN(C)CCCCN(CC1Cc2ccccc2CN1)C1CCCc2cccnc21 +O=C(c1cccc(-c2cccc(O)c2)n1)c1cccc(O)c1O +COc1cc2ncc(C#N)c(Nc3ccc(Cc4ccccc4)cc3)c2cc1OC +O=C(O)CN1CC(c2nc3ccccc3n2C2CC3CCCC(C2)N3C2CC3CCCCC(C3)C2)C1 +COc1ccc(CCc2cccc3c(=O)c4ccccc4[nH]c23)cc1 +CNC(=O)Nc1nc2cc(Oc3cccc(C#N)c3)ccc2[nH]1 +[C-]#[N+]c1ccc(NC(c2nnc(-c3ccc(F)cc3)s2)C(C)O)c(C)c1Cl +COC(=O)Nc1ccc2c(-c3c(-c4ccccn4)nn4c3CCC4)ccnc2c1 +Nc1nc2c(ncn2CCN(CCP(=O)(O)O)CCP(=O)(O)O)c(=O)[nH]1 +Nc1cccc(C(=O)n2nc(C(=O)OCC(F)(F)F)c3ccccc32)c1 +Cc1cc(Nc2nc(N3CCN(C(=O)c4ccccc4Br)CC3)nn3cccc23)n[nH]1 +Cc1c(Cl)cccc1NC(=O)c1cc(NC(=O)c2ccccc2C(F)(F)F)cc2[nH]c(N3CCC(N(C)C)C3)nc12 +COc1ccc2c(c1)OCc1c-2ccc2c1C(C)=CC(C)(C)N2 +CCCCC1(CC)CS(=O)(=O)c2cc(OCCCP(=O)(O)O)c(OC)cc2C(c2ccccc2)N1 +O=C(NCc1ccccc1)c1cccc(Nc2c(O)c(=O)c2=Nc2ccccc2)c1O +CN(CC1CNc2nc(N)nc(O)c2C1)c1ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc1 +CN(CCCCCc1ccccc1)CCCCN1CCN(CCCCCCCCCOc2ccccc2)CC1 +C=C(CCC(C)C1CCC2(C)C3CCC4C(C)C(O)CCC45CC35CCC12C)C(C)C +COP(=O)(c1ccccc1)c1c(C(N)=O)[nH]c2ccc(Cl)cc12 +COc1cc(S(=O)(=O)c2cc(F)cc(F)c2)cc2c3c(oc12)CCNC3 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+CC(C)CC(=O)N(Cc1ccccc1-c1ccccc1)C1CCNC1 +COc1cccc(OC)c1C1CC(C)C(=O)N1Cc1cccc(OC(C)C)c1 +CC1(COc2ccc(-c3ccc(F)cc3)cc2)Cn2cc([N+](=O)[O-])nc2O1 +CCc1cc2cc(NS(=O)(=O)c3ccc(C#N)cc3OC)ccc2n(CC)c1=O +CN(C)C=Nc1nsc2ccc(NS(=O)(=O)c3ccc4ccccc4c3)cc12 +COCCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2csc(C)n2)cc1 +COc1ccc(CCNC(=O)C2C(C(=O)NCCCCN3CCCC3)C3C=CC2C32CC2)cc1Br +CC1OC(=O)C2CC3CC(C(=O)Nc4cccnc4)CCC3C(C=Cc3ccc(-c4cccc(C(F)(F)F)c4)cn3)C12 +O=C(NC1CCCCCC1)c1cc2cccnc2n(CCN2CCOCC2)c1=O +COCC(NC(=O)c1ccc(Cl)s1)C(=O)Nc1ccc(N2CCOCC2=O)c(C)c1 +COc1ccc(-c2c(-c3nc(C)n4ncnc(N5CCC5)c34)cnn2C)cc1 +O=C1N(CCN2Cc3ccccc3C2)CCN1c1cscc1-c1ccccn1 +CN1CCC(c2ccccc2)=C(C(=O)OCCc2ccc3c(c2)CCO3)C1 +O=C(NC1CCc2ccc(CCN3CCN(c4nsc5ccccc45)CC3)cc21)c1ccco1 +CC1CN(C(=O)Cc2nc(N3CCOCC3)cc(=O)n2C)c2ccccc21 +O=C(Nc1ncnc2[nH]cnc12)c1cccc(-c2ccc(-c3c[nH]cn3)cc2)c1 +C=C(Br)C(=O)Nc1ccc(C(=O)C=Cc2cccc(OC)c2OC)cc1 +N#Cc1ccccc1OCC(O)CNCCNC(=O)Nc1ccc(OCCCF)cc1 +O=C1OC(c2ccc(F)cc2)CN1Cc1ccc(Cl)cc1Cl +CCCCCCCCCCCCCCC(O)C1CCC(C2CCC(C(C)O)O2)O1 +c1ccc2c(c1)CC(Nc1nc(Nc3ccncc3)nc(N3CCNCC3)n1)C2 +CC(C)(COc1cnc(-c2ccc(-c3ncc(C4(C(F)(F)F)CCC4)[nH]3)cc2)cn1)C(=O)O +CC(C)CC1C(=O)NC(C(=O)NCCc2ccccn2)CCCCNC(=O)OCCCC1C(=O)NO +Cn1c2c(c3cc(S(=O)(=O)c4cccc(OC(F)F)c4)ccc31)C1CCC(C2)N1 +CC1=C(C(=O)OCc2ccc3c(c2)OCO3)C(c2ccco2)N(C)C(=O)N1C +CN(C(=O)c1cc(-c2ccccn2)[nH]n1)c1ccc(OCB2C=Cc3ccccc3N2)cc1 +COCCOc1cc(CC2CCN(CCc3ccc4c(c3)C(O)CCO4)CC2)ccc1Br +O=C(NCC1(O)CCC(F)(F)CC1)c1cc(-c2ncc(F)cn2)ccc1Cl +N#Cc1ccc(Cn2cncc2CNC2Cc3ccccc3CN(Cc3cc(F)cc(F)c3)C2=O)cc1 +CC(NS(=O)(=O)c1ccccc1)C(=O)NC1=NN=C(c2ccc(Br)cc2)CS1 +Nc1nc(=O)n(C2CCC(NS(=O)(=O)c3cccc(-c4ccccc4Cl)c3)C2)cc1F +CC1=C(c2nc(-c3ccc(C#N)cc3)cs2)C(c2ccc(Cl)nc2)NC(=O)N1 +Cc1nc(Cl)ncc1C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=C1N(Cc2cccc3ccccc23)C(CCc2ccccc2)C(O)C(Cc2ccccc2)N1Cc1cccc2ccccc12 +C=Cc1cc(O)cc2ncn(-c3ccc(O)cc3)c(=O)c12 +Cc1ccc(C(=O)NC(C)C)cc1C#Cc1cnc2ccnn2c1 +CNCCCN(C)Cc1ccc(C(=O)Nc2cc(-c3ccccc3)ccc2O)cc1 +CCOC1CN(CC(=O)Nc2ccc(-n3ccccc3=O)cc2F)CC1NC(=O)c1ccc(Cl)s1 +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1CCCC(=O)NCC(F)(F)F +CC(C)OCC(Oc1ncnc2c1cnn2-c1ncccc1Cl)C(=O)Nc1ccccn1 +Cc1ncnc(C)c1-c1ccc(Oc2nccc3n[nH]cc23)cc1C#N +O=C(OCCN1CCN(CCCN2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1)c1ccc(OCCCN2CCCCC2)cc1 +Cc1cc(-c2cccc3c2CCN2C(=O)CN=C(n4cnc(C5CC5)c4)C=C32)sn1 +Cc1cc(S(N)(=O)=O)ccc1NC(=O)COc1ccc(Cl)cc1C(=O)c1cc(Cl)cc(C#N)c1 +CN1C(=O)C(c2ncc(C#Cc3ccccc3)cn2)C2CCCC21 +N#Cc1ccc(-c2ccc(CNCCNc3ccnc4cc(Cl)ccc34)s2)cc1 +CCC(NC(=O)c1cc(C(=O)NC(C)c2ccc(F)cc2)n2c1CSC2)c1ccccc1 +CCCN1CCc2cc(F)cc3c2C1Cc1ccc2c(c1-3)OCO2 +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2cccc(Br)c2)c(C)c1 +c1ccc(N2CCN(CCC3CCC(Nc4ncccn4)CC3)CC2)cc1 +O=C1NCc2ccc(OCCCN3CCN(c4cccc5c4COCC5)CC3)cc21 +CCNC(=O)C(=O)C(Cc1ccc(Cl)cc1)NC(=O)C(NC(=O)CCC1CCCS1)C(C)C +Cn1cncc1C(O)(c1ccc(Cl)cc1)c1ccc2nc(C#N)c(Oc3ccc(F)cc3)c(Cl)c2c1 +CC(=O)N1CCC(C(=O)Nc2ccc(NC(=O)N3Cc4ccncc4C3)cc2)CC1 +Cc1nc2cc(-n3ncc(C(=O)c4cc5cc(CN6C(C)CCC6C)ccc5[nH]4)c3N)ccc2[nH]1 +Cc1cccc(C(=O)NC2(C(=O)O)Cc3ccc(F)cc3C2)c1CC(C)C +CNC(=O)C(C)(C)CNC(=O)C(CC(O)C(N)CC(Cc1ccc(OC)c(OCCCOC)c1)C(C)C)C(C)C +Cc1cc(Nc2nc(-c3cccc(C)n3)nc3ccccc23)ccn1 +O=C(O)CN1CCC(c2nc3ccccc3n2C2CC3CCCC(C2)N3C2CC3CCCCC(C3)C2)C1 +CC(=O)NC1C(NC(=N)N)C=C(C(=O)OCCCOC(=O)c2cc(N)ccc2O)OC1C(O)C(O)CO +O=C(CC(CCCCc1ccccc1)C(=O)NC(CC1CCCCC1)C(=O)NCCc1ccccc1)NO +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccnc1SCc1ccncc1 +COc1cc2c(c(Cl)c1Cl)C(=O)C(CCN(C)CC(=O)O)(c1ccc(F)cc1)C2=O +Cc1c(C(N)=O)sc2nc(-c3ccncc3)nc(NCC(N)Cc3ccccc3)c12 +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(Nc2ccc3oc(C(=O)NCCN4CCCC4)cc3c2)n1 +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccncc1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCC3)CC2)c1)c1cccc(C(F)(F)F)n1 +O=C1CN(CC(=O)NC2CCN(Cc3ccccc3)CC2)C(=O)c2cc(Oc3ccccc3)ccc2N1 +CC(C)(CNC(=O)NCC(F)(F)F)C(c1ccccc1)c1ccc2c(cnn2-c2ccc(F)cc2)c1 +Nc1cccc(-c2cc(O)c3cc4c(cc3n2)OCO4)c1 +COc1ccc(-c2cn(-c3ccc(C(=O)O)c(O)c3)cc2C#N)cc1F +COc1ccc2c(Cc3ccccc3)c(-c3ccc(Cl)cc3)c(=O)oc2c1 +CNC(=O)N(C)CCC#Cc1cn2c(-c3ccc(C(=O)NC4CC4)cc3)cnc2c(NCC(C)C)n1 +CC(C)CN(C(=O)C(C)C)c1cccc(C(Cc2ccc(NC(=O)c3c(Cl)cccc3Cl)cc2)C(=O)O)c1 +N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)(c1ccccc1)c1ccccc1 +CCCCC1=NC(C)(C2CCCC2)C(=O)N1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC2CCN(C(=O)N3CCN(C)CC3)CC2)c2ccccc12 +O=C(NC1CCC(c2ccc(-c3nc4[nH]c(OC5COC6C(O)COC56)nc4cc3Cl)cc2)CC1)OC1CCCC1 +CCCN1CCN(c2c(-c3ccncc3)c(-c3ccc(F)cc3)c(C(=O)OC)n2C)CC1 +CNC(=O)C(CC(C)(C)C)NC(=O)c1ccc(C2CC2)c(OCC2CCOCC2)n1 +Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2cc(-c3cn(CCO)nn3)ccn12 +Cc1ccc(N2CCc3ncnc(NCc4cccc(C#N)c4)c3C2)c(C#N)c1 +Cn1cc(-c2cc(-c3ccc(N)nc3)ccc2OCC2CC2)c2cc[nH]c2c1=O +CC(C)(C)c1cccc(OCc2cc(=O)[nH][nH]2)c1 +C=C(C)CN1C(=O)N(CC(=C)C)C(Cc2ccccc2)C(O)C(O)C1Cc1ccccc1 +CC1CCC2C(C)C(Oc3ccccc3)OC3OC4(C)CCC1C32OO4 +Cc1cc(NC(=O)C(=O)c2cn(Cc3ccc(Cl)cc3)c3ccccc23)on1 +CSc1nc(C)cc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)n1 +O=C1OC2(CCC(C(=O)Nc3ncc(-c4ccccc4)cn3)CC2)c2cccnc21 +Fc1ccc(-n2c3c(c4cc(F)ccc42)CN(CCc2ccccn2)CC3)cc1 +O=C(CN1CC=CCC(NC(=O)c2ccc3ccccc3c2)C1=O)NC1CC(=O)OC1O +CC1(C)CC(=O)c2cc(C#Cc3ccccc3)cnc2C1 +COc1ccc2c(c1)[n+]([O-])c(C#N)c(-c1ccc(F)cc1)[n+]2[O-] +O=C(NC1CC1)c1cnn2ccc(N3CCCC3c3cc(F)cc(OCC(O)CO)c3)nc12 +N=C(Nc1cccc(F)c1)NC12CC3CC(CC(C3)C1)C2 +COc1cc(C(=O)n2nc(Nc3cccc(C)c3)nc2N)cc(OC)c1OC +FC(F)(F)Oc1ccc(-c2nc(Nc3ccc4[nH]ncc4c3)nc3[nH]cnc23)cc1 +COc1ccccc1C1C(C(=O)C(C)(C)C)C(=O)C(=O)N1c1ccc(-c2ccoc2)cc1 +CN1CC2CC1CN2c1cc(F)c(-c2ccnc3c(-c4cccc5[nH]ncc45)c(-c4ccncc4)nn23)cc1F +CC1(C)OCC(=O)C2=C1N=C1COC(O)=C1C2c1ccc(F)c(Br)c1 +CCCCc1nc(Cl)c(CC(=O)OC)n1Cc1ccc(NC(=O)c2cccc(C)c2NS(=O)(=O)C(F)(F)F)cc1 +CC(C)c1ccc(CNC2CCCCC2NC(=O)CNC(=O)c2cccc(C(F)(F)F)c2)cc1 +O=C(NCc1ncco1)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1 +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c3c(c2C2CC2)OCC3)cc1 +Cc1cc(NC(=O)Nc2cc(C(C)(C)C)nn2-c2cccc(C#N)c2)ccc1Oc1ccncc1 +CCSc1ccc(NC(=O)c2ccc(C(=N)N(C)C)cc2)c(C(=O)Nc2ccc(Cl)cn2)c1 +CCN(CC)CCOc1ccc2c(c1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O 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+CCCC(NC1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(C(C)(C)CN2CCOCC2)cn1 +COc1cc(-c2ccc(S(N)(=O)=O)cc2)cc(OC)c1OC +Cc1ccc(C(=O)N(C)CC23CCC4(O2)C2Cc5ccc(O)cc5C4(CCN2CC2CC2)C3)cc1 +Cc1cc(C(=O)O)nn1Cc1cc(Br)cc2sc(N3CC=CCC3)nc12 +Nc1ncc(-c2cn[nH]c2)cc1C(=O)Nc1ccncc1 +CCCCCOc1ccc2c(c1)C(=O)C(=O)C=C2c1ccccc1 +CC(C#N)=Cc1cc(C)c(Nc2ccnc(Nc3ccc(C#N)cc3)n2)c(C)c1 +COc1ccc2[nH]nc(-c3cccc(S(N)(=O)=O)c3)c2c1 +CNC(=O)C12CC1C(n1cnc3c(NCc4cccc(C)c4)nc(Cl)nc31)C(O)C2O +CONC(=O)c1ccc(C)c(Nc2nc(N(C)CC(C)(C)C)nc(N3CCCN(C)CC3)n2)c1 +Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2ccc(-c3ccn(C)n3)cn12 +CCn1c(=O)c(Oc2ccc(F)cc2F)cc2cnc(NC3CCOCC3)nc21 +COc1cc(Oc2ncccn2)ccc1-c1cc2c(cc1F)ncc1ncn(C3(C)CCN(CCO)CC3)c12 +O=C(CN1CCN(c2ccccc2F)CC1)Nc1nnc(C(F)(F)F)s1 +Cc1cc(OCc2nc(-c3cnc(OC(C)C)nc3)c(-c3ccc(OC(F)(F)F)cc3)o2)ccc1OCC(=O)O +CCCS(=O)(=O)N(CCOc1ccc2c(c1)C(Cc1cccc(Cl)c1)C(N)CC2)C1CC1 +Cc1cc(O)c(C(=O)CCc2ccc3c(c2)OCCO3)c(OC2OC(CO)C(O)C(O)C2O)c1 +Cc1c(N2CCC(C(N)c3ccccc3)C2)c(F)cc2c(=O)n(N)c(=O)n(C3CC3)c12 +C=CCCN1C2CCC1CC(OC(c1ccc(F)cc1)c1ccc(F)cc1)C2 +CNC(C)C(=O)NC(C(=O)NC1CCCN(CC(c2ccccc2)c2ccccc2)C1)C1CCCCC1 +CN(C)C(=S)NN=C(c1ccc(F)cc1)c1ccccn1 +COc1ccccc1Nc1ncc2c(n1)-c1c(c(C(N)=O)nn1C)CC2 +CC(C)(C)C(=O)CN1C(=O)C(NC(=O)Nc2cccc(N)c2)N=C(c2ccccn2)c2ccccc21 +CC(Nc1nc(N)nc(N)c1Cl)c1nc2cccc(Cl)c2c(=O)n1-c1ccccc1 +O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1ccccc1O +CCCCCCCCCCCCCCOC1C(OC)OC(CNC(=O)C2CCCN2)C(O)C1OCCCCCCCCCCCCCC +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(S(C)(=O)=O)CCO1 +C=COC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(NC(=O)CCNC(=O)OCc1ccccc1)C(C)C +CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2nc3cc(Cl)ccc3o2)CC1 +NC(=O)c1ncccc1NCC(=O)N1CCC(Oc2ccccc2C(F)(F)F)CC1 +O=C(O)c1ccc(S(=O)(=O)N(Cc2ccc(OC(F)(F)F)cc2)c2cc3ccccc3c(Br)n2)cc1 +CCN(CC)c1nc2ccc(C(O)(c3ccc(OC)nc3)c3cncn3C)cc2c(Cl)c1Oc1ccccc1 +CN(CCCNc1c2c(nc3ccccc13)CCCC2)CCCNc1c2c(nc3cc(Cl)cc(Cl)c13)CCCC2 +CC(C)CC(NC(=O)C1OC1C(=O)O)C(=O)NCCCCNC(=N)N +Cc1cccnc1CN1CCC2(CC1)C(=O)N(c1ccc(-c3ccccc3)cc1)C(=O)N2c1cc(O)ccn1 +COc1cc(-c2nc3c(c(C4(S(C)(=O)=O)CCOCC4)n2)OCC2COCCN32)c2cc[nH]c2c1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCCCCCOc1ccc(CN3CCCCC3)cc1)C2 +O=C(CN1CCSCC(NC(=O)c2ccc3ccccc3c2)C1=O)NC1CC(=O)OC1O +COc1cc(C(=O)c2sc3c(OC)cccc3c2N)cc(OC)c1OC +OCC1(N2CCC(n3c(-c4ccc(F)c(Cl)c4)nc4ccccc43)CC2)CCCCC1 +CC(=O)N1CCC(CCOc2ccc(-c3cc4c(ncn4C)c(C#N)n3)cc2C(F)(F)F)CC1 +CC(=O)N1CCC(C(=O)Nc2cnc(Nc3ccc4nc(C)sc4c3)n(Cc3ccc(Cl)cc3)c2=O)CC1 +N=C(N)c1ccc(O)c(CN2CCC(NS(=O)(=O)c3cc4nc(Cl)ccc4s3)C2=O)c1 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCc1csc(C2CCCN(C)C2)n1 +CC(C)N=C1SC(=Cc2ccc(O)c(Cl)c2)C(=O)N1CCCCc1ccccc1 +CC(C)(C)C1CSC(c2ccc(C#CCCP(=O)(O)O)cc2)SC1 +Cn1c(-c2ccccc2)nc(-c2nc(C(=O)O)cs2)c1-c1ccccc1 +Cc1ccc(S(=O)(=O)N(CC(C)C)C(CCCCNC(=O)OC2c3ccccc3-c3ccccc32)C(=O)NN)cc1 +NC(=O)Nc1sc(C#Cc2cccc(O)c2)cc1C(N)=O +FC(F)(F)c1ccc(Nc2nc(SCc3ccccc3)nc3c2CCN(c2ncccc2C(F)(F)F)CC3)cc1 +N#Cc1ccc2c(c1)CCN(CCC1CCC(NC(=O)c3ccnc4ccccc34)CC1)C2 +C=CC(=O)OCC1c2cc(OC)c(OC)cc2CC2C3c4cc(OC)c(OC)cc4CC(C(C#N)N12)N3C +O=C1N=C(O)SC1=Cc1ccc(OCCC2CCCCC2)c([N+](=O)[O-])c1 +CCCOC(=O)c1c(-c2ccccc2)nc(CC)c(C(=O)SCC)c1CC +COC(=O)NC1CCC(c2nnc(C(=O)c3nc4ccc(-c5ccccc5)cc4s3)o2)CC1 +CCOC(=O)N1CCN(C(=O)C(CCC(=O)O)NC(=O)c2cc(OCCO)cc(-c3ccccc3)n2)CC1 +COCCON=C(C)c1ccc2nnc(C(C)c3c(F)cc4ncccc4c3F)n2n1 +O=C(NCCN1CCCCC1)c1cn2c(ccc3sc4ccccc4c(=O)c32)n1 +COc1ccc2[nH]cc(CCCCN3CCN(c4cc(C)c(OC)c(C)c4)CC3)c2c1 +CCCC(CCC)C(=O)Nc1ccc(Oc2c(Cl)cc(CC(=O)O)cc2Cl)cc1Br +CCCCC(C)C1=C(c2ccccc2)C2(Nc3ccccc3)CCCC2C1 +CS(=O)(=O)N(c1ccc(-c2cnc3ccc4ccncc4c3c2)cc1)S(C)(=O)=O +CCCCCCCCNC(=O)Nc1ncnc2c1ncn2C1OC(C(=O)NCC)C(O)C1O +CC(C)CC(NC(=O)CCC(N)C(=O)O)C(=O)NCC(N)=O +COc1cc(Sc2c(-c3ccccc3)[nH]c3cccc(Br)c23)cc(OC)c1OC +Cc1ccc(-c2ccc(Cn3c(CC(C)(C)C(=O)O)nc4cc(OCc5ccc6ccccc6n5)ccc43)cc2)cc1 +CC1CCCN1CCCOc1ccc(-c2ccc(=O)n(C)n2)cc1Cl +CCn1nc(C)c(-c2ccccc2Oc2ccc(S(=O)(=O)Nc3ncns3)cc2C#N)c1C +CN(C)CCNC(=O)c1cccc2c1nc(-c1cccnc1)c1ccccc12 +CCCCN1CCCc2cc(Oc3ccc(C(N)=O)cn3)ccc2C1 +N=C(N)c1ccc(OCCCCCCCCCCCCOc2ccc(C(=N)N)cc2)cc1 +O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OC2CCC3(CCCCC3)CC2)cc1F +CC(C(=O)Nc1cc(C2CC2)[nH]n1)c1ccc(N2CCCCC2=O)cc1 +COc1ccc(C=C2SC(N3CCN(C)CC3)=NC2=O)cc1OC +Cn1cc(-c2cnc3nnc(C(F)(F)c4ccc5ncccc5c4)n3n2)cn1 +CCOc1cc(F)c(CC(CC)C(=O)O)cc1CNC(=O)c1ccc(C23CC4CC(CC(C4)C2)C3)cc1 +N=C(N)Nc1ccc(C(=O)Oc2ccc(CCN(CC(=O)O)C(=O)Cc3cccc(C(=O)O)c3)c(Cl)c2)cc1 +COc1ccc(CCNCCOc2cc(F)cc3c2OCCC3=O)cc1 +O=C(O)c1ccnc(-c2ccc3c(Nc4ccc(C(F)(F)F)cn4)ccnc3n2)c1C(F)(F)F +CSc1nc2nc3c(c(O)n2n1)CN(Cc1ccccc1)CC3 +NC(CC(=O)N1CCNCC1Cc1ccccc1)Cc1cc(F)c(F)cc1F +CC(C)S(=O)(=O)c1ccc(-c2ccc3cc(O)ccc3c2Oc2ccc(OCCN3CCCCC3)cc2)cc1 +NC1CCC(CNC(=O)C2CCCN2C(=O)CC(c2ccccc2)c2ccccc2)CC1 +Cc1nc(-c2ccc(N3C(=O)C(=O)C(C(=O)c4cc[nH]c4)C3C3CCCCC3)cc2)no1 +C=CC(=O)Nc1cccc(-c2c[nH]c3nccc(-c4[nH]c(CCCO)nc4C(F)(F)F)c23)c1 +CC(C(=O)Nc1ccc(CCCC(=O)O)cc1)c1ccc2cc(OCc3ccc4ccccc4n3)ccc2c1 +O=C(NCCCCN1CCN(c2cccc(F)c2)CC1)c1cc2ccccc2cn1 +COc1ccc(COc2cccc3oc(-c4cn5nc(SC)sc5n4)nc23)cc1 +CSCOc1cc(Cl)cc(Cl)c1C=CC1CC(O)CC(=O)O1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)NC(C)(C)C)n1)C(C)(C)CN2 +COc1cccc(-c2ccc(C(=O)N(C)Cc3ccccc3)s2)c1 +c1ccc2oc(SCCCCN3CCN(C4CCCCC4)CC3)nc2c1 +CNC(=O)Oc1ccc(Oc2ccc(S(=O)(=O)CC3CS3)cc2)cc1 +CC(=O)NCCCc1cccc2c1CC(CCCCc1ccccc1)O2 +CCCOc1cccc(Oc2cc3c(cc2NS(=O)(=O)c2ccc(OC)c(OC)c2)n(C)c(=O)n3C)c1 +CCC(C)C1CNC(=O)c2cc3cnc(Nc4ccc(N5CCN(C)CC5)cn4)nc3n21 +CC(C)n1nc(C#Cc2ccc(F)cc2)c2c(N)ncnc21 +CC(C)CCn1cc2c(nc(NC(=O)Cc3c(Cl)cccc3Cl)n3nc(-c4ccco4)nc23)n1 +O=C1N(c2cc(F)c3ccsc3c2)CCN1c1cnccc1C1CC1 +N=C(N)N1CCCC(NC(=O)CNC(=O)C(CCNC(=O)c2nccc3ccccc23)NC(=O)OCc2ccccc2)C1O +COc1cc(C(=O)NCc2cccc(C#N)c2)ccc1-c1cn[nH]c1 +COc1ccccc1-c1ccc2c(c1)C(C(C)OCCc1ccccc1Cl)=CC(C)(C)N2 +CC(=O)N1N=C(c2cc(F)ccc2F)CC1(CCCN1CCOCC1)c1ccccc1 +Cc1c(-c2cccc(C(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1C1CCOC1 +CCOC(=O)C1=C(c2ccccc2)c2ccc(OCCCCc3ccccc3)cc2C1=[N+](C)[O-] +NC(=O)c1ccc(Oc2ccc3c(c2)CCN(CCc2ccccc2)C3)nc1 +CC(C)CC(NC(=O)C(N)Cc1cccc2ccccc12)B(O)O +Clc1ccc2c(c1)C(N1CCN(CCc3ccccc3)CC1)=Nc1cccnc1N2 +CCCCCCOc1cc2c(Nc3ccc(F)c(Cl)c3)ncnc2cc1OC +CN1CCN(Cc2cc(Nc3cc(-c4ccc(F)cc4)nc4ccccc34)cc(CN3CCN(C)CC3)c2O)CC1 +Cc1ncoc1C(=O)N1CCC(NC(c2ccc(C(F)(F)F)cc2)c2cccnc2)CC1 +CC(C)(C)c1ccccc1Oc1ncccc1NC(=O)Nc1ccc(-c2ccccc2CO)cc1F +O=C(NCc1ccc(F)c(Cl)c1)c1cc2cccc(O)c2n(O)c1=O +CN(C1CCc2c(CC(=O)O)c3ccc(-c4ccc(F)cc4)nc3n2C1)S(=O)(=O)c1ccc(F)cc1 +Cc1cc(Cl)ccc1Oc1c[nH]c(COc2ccccc2)cc1=O +CN(C)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)cn2)cc1F +C=CC(=O)Nc1c(C)cccc1Nc1cc(N(C)C(=O)Nc2c(Cl)c(OC)cc(OC)c2Cl)ncn1 +COC(=O)Nc1cccc(Cn2nc(-c3cc(F)cc(F)c3)ccc2=O)c1 +CCCN(CCO)c1nc2c(C(=O)Nc3cccc(Cl)c3C)cc(NC(=O)c3ccccc3C(F)(F)F)cc2[nH]1 +CC1(C)CC(=O)C2=C(C1)Nc1c(O)cccc1N(C(=O)c1cccc(Cl)n1)C2c1ccc(OCc2ccccc2)cc1F +O=C(O)c1cccc(NC(=S)NN=Cc2ccccc2OCc2ccc(Br)cc2)c1 +CC(C)(C)C(=O)Oc1ccc(C(=O)c2ccc(OC(=O)C(C)(C)C)cc2)cc1 +CC(CSC(CCc1ccccc1C(=O)N(C)CO)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(=O)O +c1csc(C2(c3cccs3)CC3c4ccccc4C2c2cccc[n+]23)c1 +CCc1cc(-c2ccc(F)cc2)c(O)cc1OCCCOc1cccc(OC)c1CCC(=O)O +Cc1c(C(=O)NC(C)(C)c2cn3cccnc3n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +N#Cc1c[nH]c(C(=O)Nc2ccc(CCO)cc2C2=CCCCC2)n1 +CN(C)c1ccc2c(c1)CCN(c1cccc(-c3cc(Nc4ccc(N5CCOCC5)cn4)c(=O)n(C)c3)c1CO)C2=O +CCCCn1nc(C)c(C(=O)OC)c1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +CC(Cc1c[nH]c2ccccc12)(NC(=O)OC1C2CC3CC(C2)CC1C3)C(S)=NCCc1ccccc1 +c1ccc2c(c1)c(NCCCCN1CCCCC1)cc1c3ccccc3c(NCCCCN3CCCCC3)cc21 +Cc1c(C2CN3CCN(C(=O)Nc4ccc(-n5cnnn5)nc4)CC3CO2)ccc(F)c1C#N +CNC(=O)c1ccccc1Nc1nc(Nc2ccccc2OC)nc2c1CCN2 +COc1ccc(NC(=O)c2ccc(C)c(Nc3ncnc4cnc(N5CCCC5)cc34)c2)cc1C(F)(F)F +CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccc4)c(Cl)c3)c2cc1NC(=O)C=CCN1CCC(O)CC1 +Cc1ccc(CNC(=O)N2CCC(NC(=O)Nc3nc4nn(C)cc4c4nc(-c5ccco5)nn34)CC2)cc1 +O=C(NCC1(O)CCN(Cc2cc(Br)ccc2OCc2ccc(Cl)cc2)CC1)Nc1c(Cl)cccc1Cl +c1cnc(NC2CCC(CCN3CCN(c4ccncc4)CC3)CC2)nc1 +O=C(O)c1cc(Br)cc2c(=O)cc(-c3ccc(OCc4ccc5ccccc5n4)cc3)oc12 +Cc1cc(C(=O)NCc2cc(Cl)ccc2-n2cnnn2)cc(-c2c[n+]([O-])ccc2C(C)C)c1 +Cc1nc(N2C(=O)CSC2c2c(F)cccc2F)sc1C +O=C(c1nc2ccccc2[nH]1)N1CC(c2nccnc2N2CCCC(O)C2)C1 +O=C(O)C(O)=CC(=O)C1(Cc2ccc(Cl)cc2)CCN(CC2CCCCC2)CC1 +Cn1c(=O)c(-c2c(Cl)ccc(C(=O)O)c2Cl)cc2cnc(Nc3ccccc3)nc21 +COc1ccc(-c2[nH]cnc2-c2cc(OC)c(OC)c(OC)c2)cc1F +c1ccc(OCC2CN(CCN3CCc4ccccc43)CCO2)cc1 +CC(C)C(CN1CCC(C)(c2cccc(O)c2)C(C)C1)NC(=O)C1Cc2ccc(O)cc2CN1CCF +O=C(c1cccnc1)N1N=C(c2ccc(O)cc2)CC1c1ccccc1Br +Oc1ccc2oc(-c3ccccc3OCc3ccccc3)cc2c1CN1CCC(N2CCCCC2)CC1 +Cc1ccc(F)c(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c1 +COc1cccc2c1NC(=O)C(NC(=O)C(CCC(F)(F)F)C(CCC(C)(F)F)C(N)=O)N=C2c1ccccc1 +CCC(CC)=C(c1ccc(OCCN2CCCCCC2)cc1)c1ccc(OCCN2CCCCCC2)cc1 +Cc1nc(NC2CCCC2)c2nnn(-c3ccc(C(C)C)cc3Br)c2n1 +CC1=CC(C2Oc3c(F)cc(F)cc3-c3ccc4c(c32)C(C)=CC(C)(C)N4)CCC1 +CN(Cc1ccccc1)C(=O)c1cccc(NCc2nc(-c3ccncc3)n[nH]2)c1 +CCCCCN1C(=O)C(=NNC(=O)CC(C)C)c2ccc(OC)cc21 +Nc1nc2ccc(S(=O)(=O)n3c(CCCC(=O)O)cc4cc(Cl)ccc43)cc2s1 +CN(C)c1ccc(-c2c(N)ncnc2C#Cc2ccc(N3CCOCC3)nc2)cc1 +Oc1ccc(CN(Cc2cccs2)Cc2ccc(O)c3ncccc23)c2cccnc12 +COc1ccc2[nH]c(=O)c3sccc3c2c1-c1ccc(CCN)c(F)c1 +COc1ccc2c(c1)-c1nc(-c3ccc(C4(N)CC(O)(C5CC5)C4)cc3)c(-c3ccccc3)n1CO2 +CC1(c2ccc(N)cc2)C(=O)Nc2cc(Cl)cc(Cl)c2C1=O +CC(=O)OC(C(=O)Nc1cccc2c1C(=O)C(=O)NC2=O)c1ccccc1 +CNC(=O)N1CCCC1c1cc(-c2ccncc2)c(-c2ccc(F)cc2)[nH]1 +CCCOC1C(O)CC(=CC=C2CCCC3(C)C(C(C)SCCCC(O)(CC)CC)=CCC23)CC1O +COc1ccc2c(c1)-c1c(ssc1=S)C(C)(C)N2C(=O)c1ccccc1F +CNC(C)C(=O)NC(C(=O)N1CC2CCCN2CC1C(=O)NC1CCC(F)(F)c2ccccc21)C1CCCCC1 +COc1cc(CNCCCCN2CCC(Cc3ccccc3)CC2)cc(OC)c1OC +COc1ccc(S(=O)(=O)n2c(=O)cc(-c3ccccc3)c3ccccc32)cc1OC +COc1ccccc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1C)N(c1cc(Cl)cnc1C)C2=O +COc1ccc(C2(CNC(=O)c3cc(C)ccc3Cl)CCCC2)cc1 +Cn1cnc(S(=O)(=O)NCCOc2ccc3c(c2)C(Cc2ccc(Cl)c(Cl)c2)C(NC=O)CC3)c1 +Cc1cc(-c2cccc(C(=O)c3cccc(O)c3)n2)ccc1O +COc1ccc(CNc2ccc(-c3ccc(CC(N)C(=O)O)cc3)nn2)cc1OC1CCCC1 +CC1CC2C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC2(C)C1(O)C(=O)CO +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(F)cc3F)CC2)nc2ccsc12 +CC(C)=CCc1cc(C(=O)C=Cc2ccc(O)c(O)c2)c(O)cc1O +CC(C)(C)c1nc(N2CCN(CCCCN3CCC(=O)CCC3=O)CC2)cc(C(F)(F)F)n1 +FC(F)(F)c1cc(C(F)(F)F)c2[nH]c(N3CCN(c4ncccc4C(F)(F)F)CC3)nc2c1 +Cc1cc(NCC(N)c2cccc(F)c2)n2nc(NC(CC#N)c3cccc(Cl)c3)nc2n1 +CC(C)Oc1ccnc2[nH]cc(-c3ccnc(N)n3)c12 +O=S(=O)(c1c(-c2nc3ccc(F)cc3[nH]2)[nH]c2ccc(Br)cc12)N1CCCC1 +CC(C)c1noc(-c2cc(Cl)nc(Oc3ccc4c(c3)N(S(=O)(=O)c3ccc(Cl)cc3)CCC4)c2)n1 +O=C(O)c1ccc(S(=O)(=O)N(Cc2ccc3occc3c2)c2ncc(C(F)(F)F)cc2Cl)cc1 +COc1cccc2cc(C(=O)NCCCCCCCNc3c4c(nc5ccccc35)CCCC4)oc12 +CC(C)c1ccccc1OCC(O)CN1CCC(N2C(=O)c3cccc4cccc(c34)C2=O)CC1 +CC(=O)N1CCc2ccc(C(=O)CCCN3CCC(c4ccc(Cl)cc4)CC3)cc2C1 +N#Cc1ccc(NC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)cc1 +Cc1cncc(N2CC3CN(C(=O)c4ccc(F)cc4-n4nccn4)CC3C2)n1 +O=C(O)C12CCN(c3nc(-c4ccccc4OCc4ccc5c(c4)CCN(C4CCOCC4)C5)cs3)CC1C2 +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3n[nH]cc3C3(c4ccccc4)CC3)CC2)C(c2ccccc2)C1 +NS(=O)(=O)c1ccc(CNS(=O)(=O)c2c(F)c(F)cc(F)c2F)cc1 +CN(C)Cc1nccn1-c1ccc(N2CCC(NS(=O)(=O)c3cc4ccc(Cl)cc4s3)C2=O)c(F)c1 +CC(C)OC(=O)c1ccc(Oc2ccc3c(c2)COB3O)cc1 +CC(O)CNC(=O)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CC(=O)N(C)C)c1=O 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+O=C(CCCCCCc1ccccc1)c1ncc(CCCCCCl)o1 +Cc1ccc(-c2nc3ccccc3s2)cc1NC(=O)c1cc([N+](=O)[O-])c(N2CCNCC2)cc1Cl +O=C(Oc1ccc(Cl)cc1)N1CCN(c2nc(C3=NOC(c4ccccc4)C3)cs2)CC1 +COc1ccc2c(c1)c(CCN1CCCCC1)cn2S(=O)(=O)c1ccccc1 +Cc1ccccc1Oc1ccc(C=C(NC(=O)c2ccccc2)C(=O)O)cc1 +CC(C)c1cc(Oc2c(Br)cc(NC(=O)C(=O)O)cc2Br)ccc1O +Cc1nc(N)ccc1CNC(=O)C1C=CCn2c(=O)n(C(CSc3ccc(Cl)c(Cl)c3)C(=O)OC3CCCCC3)c(=O)n21 +NC1CCC(Nc2cc(-c3nc(NCC4CCOCC4)cnc3C(F)(F)F)c(Cl)cn2)CC1 +NS(=O)(=O)Cc1nnc(C(=O)c2nc3ccc(-c4ccccc4)cc3s2)o1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1 +CCc1cccc(C2(NCC(O)C(Cc3cc(F)cc(F)c3)NC(C)=O)CCCCC2)c1 +O=C(O)CCCCN1CCc2c(c3ccccc3n2Cc2cccc(C=Cc3ccc4ccc(Cl)cc4n3)c2)C1 +O=C(Nc1cc2ccc(-c3cc(CO)ccc3Cl)cc2cn1)C1CC1 +COCCCN1CCN(C(=O)N2Cc3c(NC(=O)c4ccccn4)n[nH]c3C2(C)C)C(C)C1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(Cl)cc4)cc3)[nH]c2n(CCC)c1=O +N=C(N)c1ccc(NC(=O)COc2ccc(CC(NC(=O)c3ccc4ccccc4c3)C(=O)O)cc2)cc1 +CN(C)C(=O)Cc1ccc2nc(NC(=O)c3cccc(Cn4nc(-c5cccnc5)ccc4=O)c3)[nH]c2c1 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+CC1CN2c3c(cc4c(-c5ccccn5)noc4c3Cl)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +N#Cc1cccc(-c2cc(N3CC(N)C(c4cc(F)c(F)cc4F)C3)ncn2)c1 +Cc1cc(CN2CCCC(Nc3nc(N)n4nc(-c5ccco5)nc4n3)C2)no1 +CC(=O)N(C1=C(N(C)C)C(=O)c2ccccc2C1=O)c1cccc(O)c1 +CCC#CCOC1CC2C(CCC3(C)C(=O)CCC23)C2(C)C=CC(=O)C=C12 +CCc1c2c(nc3ccc(OCC[n+]4cccc(CO)c4)cc13)-c1cc3c(c(=O)n1C2)COC(=O)C3(O)CC +N#Cc1cc(-c2ccc3c(c2)C2(CCCCC2)C(S)=N3)ccc1F +FC(F)(F)c1ccnc(Nc2cc(-c3ccccc3)cc(N3CCOCC3)c2)n1 +COCCCOc1cc(CC(CC(N)C(O)CC(C)C(=O)NCCCCC(N)=O)C(C)C)ccc1OC +COc1ccc(Cn2cc(-c3cc(C(F)(F)F)nc(S(C)(=O)=O)n3)ccc2=O)cc1 +CN1CCC(NC(=O)N2c3ccccc3C(=O)Nc3cccnc32)CC1 +COc1ccc(CCN2CCC(c3nc(COCC(F)(F)F)c(-c4ccc(F)cc4)o3)CC2)cc1S(N)(=O)=O +CC(C)Cc1nn(C)c(=O)c2c(SCCCO)n(Cc3ccc(Cl)nc3)cc12 +CCN(CCCl)CCCCCNc1c2ccccc2nc2ccc(OC)cc12 +Cc1c(C#N)ccc2nc(CCc3nc(N4CCCC4)nn3C)nn12 +Cc1cc(N)nc2cc(CNCCc3ccc(C#N)cc3)ccc12 +CC(=O)Nc1cc(C(F)(F)F)c(-c2nc(N3CCOCC3)nc(N3CCOCC3)n2)cn1 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1-c1cc(N2CCOCC2)nc(N2CCOCC2)c1 +O=C(CC1CCc2ccccc2N1S(=O)(=O)c1ccc(Cl)c(Cl)c1)NCCN1CCN(c2ccncc2)CC1 +O=C1Nc2ccc(Cl)cc2C(C#Cc2ccccn2)(C(F)(F)F)N1 +Cc1cc(COc2ccc(C(=O)NC3CN(S(C)(=O)=O)CC34C(=O)NC(=O)NC4=O)cc2)c2ccccc2n1 +O=C(CO)NCC1CCCc2cc(S(=O)(=O)c3cccc(F)c3)ccc21 +O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccccc3)n(-c3ccc(Cl)cc3)n2)c1 +CN(CCCNc1c2c(nc3ccccc13)CCCC2)CCCNc1c2c(nc3ccccc13)CCCC2 +Cc1nc(-n2ccc(C3CC3)cc2=O)sc1C(=O)NCc1ccccc1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)nc(NCc4ccccc4-n4ccnc4)nc23)N1 +Nc1nc(=S)[nH]c2c1c(-c1ccc(Br)cc1)cn2-c1ccc(S(N)(=O)=O)cc1 +Clc1ccc(OCCc2ccccc2)c(CCN2CCOCC2)c1 +CCOC(=O)C1=C(C)N=C(C[S+]([O-])c2ccc(OC)cc2)C(=C(O)OCC)C1c1ccccc1C(F)(F)F +COC1C(c2ccc(C#N)c(Cl)c2C)=NN2CC(F)CC12 +O=C(NC1CCNCC1F)C1CCC2CN1C(=O)N2OS(=O)(=O)O +CN(c1ncnc2ccc(C#CCNC(=O)c3cncn(Cc4ccc(F)c(F)c4)c3=O)cc12)C1CCCCC1 +Cc1cc(COc2ccc(NC(=O)C3C(C(=O)NO)CCCN3CC3CC3)cc2)c2ccccc2n1 +NC(=O)c1cccc2[nH]c(-c3ccc(CN4CCOCC4)cc3)nc12 +CCNC(=O)Nc1sc2ccccc2c1C(=O)N1CCN(C2CCN(C(=O)OC(C)(C)C(F)(F)F)CC2)CC1 +Cn1nc(S(N)(=O)=O)sc1=NS(=O)(=O)c1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +O=C1CCCC(=O)C1C(=O)c1ccccc1[N+](=O)[O-] +CN1CCC(COCc2cc(C(F)(F)F)cc(N3CCC(C#N)CC3)n2)(c2ccc(F)cc2)CC1 +O=C(NS(=O)(=O)N1CCC1)c1cc(Cl)c(OCC23CC4CC(CC(C4)C2)C3)cc1F +CN(C(=O)C1CCCCC1)c1ccc2c(c1)nc(NC(=O)c1ccc(C#N)cc1)n2CCc1ccccc1 +CC(NC(=O)Nc1cc2[nH]nc(-c3ccc4nn(C)cc4c3)c2cn1)c1cccc(Cl)c1 +Cn1ncc(NC(=O)c2nc(-c3c(F)ccc(F)c3F)sc2N)c1C1CCC(N)C(F)CO1 +CCCCCC(O)C1C(=O)NC(C(=O)O)(C(O)C2C=CCCC2)C1(C)O +CCOC(=O)CNC(=O)c1ccccc1[Se][Se]c1ccccc1C(=O)NCC(=O)OCC +Cc1ccc(NC(=O)c2cccnc2SCc2ccncc2)cc1C +COc1ccc(OC(=O)c2ccc3c(c2)CCC2=C(C)C(=O)CCN23)cc1 +Clc1ccc(-c2cc(C3CCN(Cc4cccc(Cl)c4)CC3)[nH]n2)cc1 +Nc1c2ccccc2nc2c(C(=O)NC34CC5CC(CC(C5)C3)C4)cccc12 +Cc1n[nH]c2ccc(-c3cncc(OCC(N)Cc4cccc(C(F)(F)F)c4)c3)cc12 +CC(=O)OC(C(=O)Nc1cnn(Cc2c(C)noc2C)c1)c1ccccc1 +CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1cc(O)ccc1n2CCF +COc1ccc(S(=O)(=O)Nc2ccc3nc(NC(C)c4ccccc4)oc(=O)c3c2C)cc1 +O=C(Cc1ccc(F)cc1)Nc1cccc(-c2n[nH]c3ccc(-c4nc[nH]n4)cc23)c1 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+O=C1CC(C(=O)Nc2cc(-c3cccc(OCC(F)(F)F)c3)n(-c3ccccc3)n2)CN1 +CS(=O)(=O)Cc1cccc(Nc2nccc(Oc3ccc4c(C(N)=O)cccc4c3)n2)c1 +CCCCCOc1c(OC)ccc2cc(C(=O)NCCc3ccc(O)cc3)c(O)nc12 +CS(=O)(=O)Nc1ccc(-c2coc3cc(C#CC4CN(C(=O)CO)C4)ccc3c2=O)cc1 +O=C(Nc1cc(-c2cn[nH]c2)cc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1 +O=C(c1cc(O)c(-c2cc(Cl)cc(Cl)c2)c(O)c1)c1cccs1 +CC1CC(O)C2(O)OC3CC4(CO)C(CCC5C4CC(O)C4(C)C(C6=CC(=O)OC6)CCC54O)CC3OC2O1 +CCCC(=NNS(=O)(=O)c1cc([N+](=O)[O-])ccc1C)c1cnn2ccc(C#N)cc12 +C#Cc1cccc2nc(Cn3nc(-c4cccc(O)c4)c4c(N)ncnc43)n(Cc3cccc(OC)c3)c(=O)c12 +COc1c(C)cccc1-c1cc(Cl)cc(C(CC(=O)O)c2ncc(C)s2)c1 +Cc1ccc(C=CC(=O)c2ccc(O)c(CN3CCOCC3)c2)o1 +O=C(NC1CCOC2CCCC(C(=O)O)N2C1=O)C(S)Cc1ccccc1 +Cc1ccc(S(=O)(=O)N(CC(C)C)C(CCCCNC(=O)N(C)Cc2ccccc2)C(=O)O)cc1 +O=C(Oc1ccc(-c2ccc(F)cc2F)cc1C(=O)Nc1cccc(Cl)c1)c1ccccc1 +CN(CCCCn1c(=O)oc2ccccc21)Cc1ccc(Cl)cc1 +NC(=O)c1ccccc1OCCCN1CCN(c2cccc3c2ccn3Cc2cccc(Cl)c2)CC1 +COc1ccc(C(=O)C2C(=O)C(=O)N(c3ccc(-c4ccco4)cc3)C2C2CCCCC2)cc1 +CC(=O)C1=C(C)NC(=O)N(C(=O)NCCCN2CCN(c3ccccc3C(N)=O)CC2)C1c1cc(F)c(F)c(F)c1 +CC(C)(C)ON=C(c1cc(Br)c(F)cc1O)c1c(O)ccc[n+]1[O-] +CCNC(=O)C1OC(n2cnc3c(N)nc(C#CC(OCC)OCC)nc32)C(O)C1O +CNC(=O)C1Cc2ccccc2N1C(=O)Cc1ccc(Cl)cc1 +Cc1ccccc1-c1ccc2nc(N)c(CC(C)C(=O)NCC3CCCCC3)cc2c1 +C=CC(=O)Nc1ccc(S(=O)(=O)N2CCCN(C(=O)OCc3ccccc3)CC2)cc1 +O=C(OCc1ccccc1)N(O)CCC#Cc1ccc(OCCCCN2CCN(C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1 +Cn1ncc2c(Nc3nc(NC4CCCCC4N)nnc3C(N)=O)cccc21 +COCC(NC(=O)Nc1cc2[nH]nc(NC3COC3)c2cn1)c1ccccc1 +O=S(=O)(NCCCCc1c[nH]cn1)c1ccc(OC(F)(F)F)cc1 +OC1C(Cn2cncn2)OC(c2ccc(Cl)c(Cc3ncc(-c4ccco4)s3)c2)C(O)C1O +NS(=O)(=O)c1ccc(CCNS(=O)(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +CC(C)Cn1c(=O)n(C)c(=O)c2[nH]c(Cc3cncc4ccccc34)nc21 +Nc1noc2cccc(-c3ccc(NC(=O)Nc4ccccc4)cc3)c12 +COc1ccc(C2=C(c3nn[nH]n3)C(=O)NC(c3ccc(OCCCC(F)(F)F)cc3)(C(F)(F)F)C2)cc1 +O=C(c1cccc2ccccc12)N1Cc2ccccc2CC1COc1ccc(F)cc1F +Cc1oc(-c2ccccc2)nc1CCOc1ccc2c(c1)CCC2C(CC(F)(F)F)C(=O)O +O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1cc(Cl)cc(Cl)c1 +CCn1cc(-c2cc3c(-c4cccc(N5CCNCC(C#N)C5)n4)n[nH]c3cn2)cn1 +O=C(O)c1ccc(CNC(=O)c2cc(Cl)ccc2Oc2ccc(F)cc2)cc1 +N#Cc1ccc(C(=O)Nc2ccc(F)c(C34CC3CCSC(N)=N4)c2)nc1 +Cc1ccc(NC(O)c2ccc(CN3CC(N(C)C)C3)c(C(F)(F)F)c2)cc1Nc1nccc(-c2cncnc2)n1 +CC1(C)CC(=O)CC(=NNC(=O)c2cc3ccccc3cc2O)C1 +COc1cc(OC)nc(Sc2cccc([N+](=O)[O-])c2C(=O)O)n1 +COc1ncccc1-n1nc(C)c2c1C(=O)N(c1cc(C)c3nnc(C)n3c1)C2c1ccc(Cl)cc1F +CCCC1(CCc2ccccc2)OC(=O)C(C(CC)c2cccc(NS(=O)(=O)c3ccc(C#N)cc3)c2)=C(O)O1 +CC(C)C1CN(C(=O)Nc2ccccc2)c2ccc(-c3ccc(C4CCC(CC(=O)O)CC4)cc3)cc2O1 +Fc1ccc(C2=NN(c3nc(-c4ccc(Br)cc4)cs3)C(c3cccs3)C2)cc1 +CC(C)(C)C(=O)C1C(=O)C(=O)N(c2ccc(-c3cccs3)cc2)C1c1cccc[n+]1[O-] +CN1CCN(Cc2ccc(-n3cc4cccc(C(N)=O)c4n3)cc2)CC1 +O=C(Cc1ccc(F)cc1)Nc1ccc2cc(C(=O)NO)sc2c1 +Cc1cc(C(=O)O)nn1Cc1cc(Cl)cc2nc(-c3ccccc3)oc12 +COc1cccc(CNc2ccc3c(c2)C24CCCCC2C(C3)N(CC2CCC2)CC4)c1 +Brc1ccc2[nH]cc(C(c3ccccc3)c3c[nH]c4ccc(Br)cc34)c2c1 +Cc1ccc(-c2csc(NN=C3CCc4c(C)cccc43)n2)cc1 +COc1cc(N)c(Cl)cc1C(=O)NC1CCN(CC2CCN(CC(C)CN)CC2)CC1 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+O=C(Nc1cnc(Oc2ccc(-c3cnc(N4CCCC4=O)s3)cc2)nc1)Nc1cc(C(F)(F)F)cnc1-c1ccccc1 +NC(=O)c1cccc2c(NCC3CC=CC(=NC(O)c4ccn[nH]4)C3)ncnc12 +COc1cc(OC)cc(-c2cc3cnc(NCCCN4CCOCC4)nc3nc2NC(=O)NC(C)(C)C)c1 +Cc1cccc(-c2nc(Nc3ccncc3)c3sccc3n2)n1 +O=C(CN1C(=O)C2(OCCO2)c2ccccc21)c1cccc(Br)c1 +CCc1c(C)nc(O)c(N(C)C)c1C(=O)c1cccc(C=CC#N)c1 +COc1ccc(CNC(=O)COc2ccc(-c3oc4cc(O)c(C(=O)O)cc4c3C#Cc3cccc(Cl)c3)cc2)cc1OC +Cc1ccc(-c2ccc(N3CCOc4ncnc(N)c4C3=O)cc2)c(Cl)c1 +Cc1cccc(N2CCN(Cc3ccc(F)cc3Cl)C(=O)C2=O)c1N1CCOCC1 +Cc1ccc(C)c(Cn2cc(CCNc3ncnc4c3ncn4C3OC(C(=O)NC4CC4)C(O)C3O)c3cc(C)ccc32)c1 +COc1cccc(NC(=O)Cn2cc(Oc3ncnc4cc(OCCN5CCCC5)c(OC)cc34)cn2)c1 +O=C(Cn1cc(Cc2cncnc2)c(=O)nc1SCc1ccc(F)cc1)NCc1ccc(-c2ccccc2)cc1 +NC1=Nc2ccc3cc2CN1C(C1CCCCC1)CCC(=O)N(C1CCCCC1)CCc1cccc(c1)O3 +CCS(=O)(=O)Nc1ccc(CCNC(=O)c2ccnc3[nH]c(-c4ccc(F)cc4)nc23)cc1 +CCOCCC1(Oc2ccc(Oc3ccc(Br)cc3)cc2)C(=O)NC(=O)C(N)C1=O +CN1CCC(c2ccc(Nc3nc4c(Nc5ccccc5CN(C)S(C)(=O)=O)cccn4n3)cc2)CC1 +CSc1cccc(NC(=O)C2CCCN2S(=O)(=O)c2ccc(C)c(Cl)c2)c1 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+COc1cc(C2OC(c3ccc(OC(C)C(O)c4ccccc4)c(OC)c3)C(C)C2C)ccc1OC(C)C(O)c1ccccc1 +CC1C(Nc2ccc(C(F)(F)F)cn2)CCCN1C(=O)c1cc(Cl)ccc1-n1nccn1 +COc1cc(CC2CN=C(N)N=C2N)cc(OC)c1OCc1ccccc1 +CCc1c(C(=O)Nc2cc(S(=O)(=O)N(CC)CC)c(C)cc2O)[nH]c(C)c1C(C)=O +O=C(O)c1ccc2c(c1)nc(NCc1cccnc1)c1ccsc12 +CCCS(=O)(=O)N1CCC(CNC(=O)c2cccc(C)c2)(c2ccccn2)CC1 +COc1ccc2c(c1Cl)C(=O)N(Cc1c(C)cc(C)[nH]c1=O)CCC2 +CNC(C(=O)NC(C(=O)N(C)C(CC(C)C(=O)O)C(C)C)C(C)(C)C)C(C)(C)c1cn(C)c2ccccc12 +C#CCNC1CCc2ccc(OC(=O)N(C)c3ccc(OC)cc3)cc21 +COc1ccc(C(=O)Nc2nc(-c3ccccn3)cc3ccccc23)cc1 +O=C(NCP(=O)(O)CC1(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O)CCCC1)OCc1ccccc1 +CNC(=O)c1ccc2[nH]c(-c3ccc(Oc4c([N+](=O)[O-])c(C)nn4-c4ccccc4)cc3)nc2c1 +O=C(NC(Cc1ccc(F)c(Br)c1)C(=O)O)c1ccc(Br)cc1NS(=O)(=O)c1cccc2nsnc12 +Oc1ccc(C2Nc3ccccc3-c3ccnc4[nH]cc2c34)c(F)c1 +CC(C)CC(NC(=O)C1OC1C(=O)O)C(=O)NCCCCNC(=O)CCCCC1CCSS1 +CC(=O)NC(COCc1cc(C)cc(C)c1)Cc1c[nH]c2ccccc12 +CC(C)(C)OC(=O)Nc1cccc(CCNC(=O)CC2(C)CC3(CCCCC3)OO2)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2-c1ccc2cn[nH]c2c1 +N#Cc1c(-c2ccccc2)nc2[nH]nc(C3CC3)c2c1-c1ccccc1 +NC(=NO)c1cn(C2OC(CO)C(O)C2O)c2nnnc(N)c12 +c1ccc(-n2cnc3cc(-c4ccc(OCCN5CCCCC5)cc4)ccc32)cc1 +Nc1cc(CN2CCC(F)(C(=O)N3CCC(N4CCNc5ccccc5C4)CC3)CC2)ccn1 +CC(C)CC(=O)NCc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +O=C(CC1CCCC1)Nc1ccc(NC(=O)N2Cc3ccc(Br)cc3C2)cc1 +CN1C(=O)CN(Cc2ccc(-c3cccc(CN4CCCCC4)n3)cc2)C1=O +Cc1ccc(C(=O)c2oc3cccc(OCCCNCc4cccnc4)c3c2C)nc1 +Cc1cc(C#N)ccc1C1CCN(S(=O)(=O)CC2(C(=O)NO)CCN(C(=O)OC3CCNC3)CC2)CC1 +CCC(C)c1ccc(OS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +CS(=O)(=O)c1ccc(-c2sc3ncnn3c2-c2cccc(F)c2)cc1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(C)C2 +CN(C)C(=O)c1cc(-c2ccc(Cl)cc2Cl)n[nH]1 +CCC(C)c1ccc(O)c(NC(=S)NC(=O)c2cccnc2)c1 +CCOC(CC(=O)O)c1ccc(Oc2ccc(Cl)c(Cl)c2)cc1 +CC=CC=CC(=O)N1Cc2cc(OCCc3nc(C(C)=CCC)oc3C)ccc2CC1C(=O)O +CC(=O)c1cccc(NC(=O)NCCCN2CCC(Cc3ccccc3)CC2C(C)(O)O)c1 +CCCCN(CC)Cc1cnc(NC(=O)C(CCC)NC(=O)Cc2cc(F)cc(F)c2)s1 +COc1ccc(-c2ccc(C(=O)Nc3ccc4cc(CN5CCCC5)cnc4c3)cc2)cc1 +CON=C1C(c2c(O)[nH]c3cc(Br)ccc23)=Nc2ccccc21 +CC12CCC(=O)C(Br)=C1c1ccc3[nH]ncc3c1C2 +CC(C)C1(c2cccs2)OCC(=O)Nc2ccc(-c3ccc(C#N)n3C)cc21 +O=C(NCc1ccc(F)cc1)c1nc(Cc2ccccc2)nc(O)c1O +CC(CN1CC(C)(C)c2cc(F)ccc21)NC(=O)OC(CC1CCCCC1)C(=O)N1CCSCC1 +CCCCCN1CCc2cc(C(=O)CCC3CCN(Cc4ccccc4)CC3)ccc21 +CC(C)(C)c1ccc(C2(N3CCc4cc(S(=O)(=O)Nc5ccc(CCCC6CCCC6)cc5F)ccc4C3)CC2)cn1 +COc1ccc(C(C(=O)N2Cc3ncn(Cc4ccccc4)c3CC2C(=O)O)c2ccc(OC)cc2)cc1 +Cn1cc(CNC(=O)c2cc(NC(=O)c3cc(-c4ccccn4)c(F)cc3Cl)n(-c3ccccc3)n2)cn1 +CC(=O)c1ccc(CN2CCC(Nc3cc(Oc4c(C)cc(C)cc4C)n4ncnc4n3)CC2)cc1 +COc1cccc(-c2cn(C3CC(CNCCO)C3)c3ncnc(N)c23)c1 +CCCCCCCCCCCCCCONC(=O)C(N)COP(=O)(O)O +CC(C)(O)C(NC(=O)Nc1cc2[nH]nc(N3CCOCC3)c2cn1)c1ccccc1 +CCCCc1ccc(-c2ccc3c(C)c(-c4ccc(C(=O)O)c(O)c4)[nH]c3c2F)cc1 +O=C(NO)C(CNS(=O)(=O)c1cccc(C(F)(F)F)c1)NS(=O)(=O)c1cccc(C(F)(F)F)c1 +Nc1nc(Cl)c2ccn(C3OC(CO)C(O)C3O)c2n1 +CCCC(C(=O)NO)C1CCN(c2ccc(OCc3cc(C)nc4ccccc34)cc2)C1=O +CCOc1cc2ncnc(Nc3ccc(F)c(Cl)c3)c2cc1NC(=O)C=CCN(C)C1CC1 +CCCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(C(=O)O)c(C)nc3ccccc23)cc1 +Fc1cc(Cl)ccc1C(c1cccnc1)N1CCN(c2ccccc2)CC1 +O=C(NCCCCNc1ccnc2cc(Cl)ccc12)C(=O)NC1C(=O)N(c2ccc(Cl)cc2)C1C=Cc1ccccc1 +CN(CC1(C)Cn2cc([N+](=O)[O-])nc2O1)c1ccc(OC(F)(F)F)cc1 +O=C(C=Cc1cccnc1)N1CCN(Cc2ccc(OC(F)(F)F)cc2)CC1 +CCCN1CCC2(CC1)Oc1ccc(Br)cc1C1CC(c3ccc(OC)cc3)=NN12 +CN(c1ccc(Cl)cc1)c1ccc(C(=O)c2ccc(C(=O)c3cccs3)c(C(=O)O)c2)nc1 +O=C(Nc1nc2ccccc2c2cn(-c3ccccc3)nc12)c1ccsc1 +O=C(Nc1ccc(-c2ccccc2)cc1)C1CCCN1c1ccc(-n2ccnc2)cc1 +CN(C(=S)SSC(=S)N(C)c1ccccc1)c1ccccc1 +COc1cc2c(cc1OC)C(=O)N1C=C(c3c(F)cccc3F)CC1C=N2 +COc1cc(Nc2nnc(-c3ccccc3)o2)ccc1-c1cnco1 +Cc1cccc(OCC2CC3CCC2N3C(=O)c2ccccc2-c2nc(C)no2)n1 +N=C(N)c1ccc2cc(C(=O)Nc3ccc(C(N)=O)cc3)ccc2c1 +CS(=O)(=O)c1ccc(CN2CCN(c3cn[nH]c3-c3cc(Cl)c(O)cc3O)CC2)cc1 +CCOc1c(Cl)cc(Cl)cc1-c1cnc(C(C)NC(=O)C2(NC(=O)C(F)(F)F)CC2)c(F)c1 +COc1ccc(COc2cc(C(N)=O)c3ncnc(NC(CN(C)C)c4cccc(F)c4)c3c2)cc1 +CNc1cc(-c2ccc(N3CCN(C)CC3)cc2)c(-c2cc(F)c(O)c(F)c2)cn1 +C=CCOC(=O)c1c(C)[nH]c2c1C13CC1CN(C(=O)C=Cc1ccc(OC)cc1)C3=CC2=O +Cc1cc(C(N)=O)ccc1-n1c(CCC(=O)O)ccc1-c1ccc(-c2ccoc2)cc1 +CC(C)(C)OCC(O)CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +COC1CCC(Nc2ccc3nnc(-c4cccc(C(F)(F)F)c4)n3c2)CC1 +O=C(c1ccc(-c2ccc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3c2)cc1)N1CCCCC1 +N#CCC(=O)N1CCC(F)(F)C12CCN(c1ncnc3[nH]ccc13)C2 +Cn1cc(-c2cccc(N3CCn4c(cc5c4CCCC5)C3=O)c2CO)cc(Nc2ccc(N3CCOCC3)cn2)c1=O +O=C(Nc1nc2ccccc2s1)c1cccc2c1CN(c1ccc(-c3cnn(-c4ccccc4)c3)c(C(=O)O)n1)CC2 +CN(CC(CCN1CCCCC1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 +CCCCCC(O)c1ccc(N2C(=O)CCC2COCc2ccc(C(=O)O)o2)cc1 +NC1=NC(CCc2ccc(OC(F)(F)F)c(F)c2)CO1 +CC(Oc1cccc(C#Cc2ccc3ccc(Br)cc3n2)c1)C(=O)O +CC1CC(c2ccccc2-c2ccccc2)N(Cc2ccc(OC(F)(F)F)cc2)C1=O +CNC(=O)C1CCCN1c1nc(Nc2[nH]nc3c2CN(C(=O)NC2CC2c2ccccc2)C3(C)C)nc(OC)n1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4cccc(-n5cnnn5)n4)CC3CO2)c1C +CCc1cc(C(=O)NC2CC(C(=O)Nc3ccccn3)N(C(=O)c3coc4ccccc34)C2)n(C)n1 +O=C(CCC1CCN(Cc2ccccc2O)CC1)c1cc2c3c(ccn3C(=O)CC2)c1 +Cc1cc(C)c(S(=O)(=O)NC(C)CNc2cccc3c2cnn3-c2cncnc2)c(C)c1 +CCOC(=O)C1CCCN(C(=O)CCC(=O)N(CC(C)(C)C)c2ccc(Cl)cc2C(O)c2ccccc2OC)C1 +NC1=CC(=O)c2ccc(-c3nc(C(=O)OCCO)cc4c3[nH]c3ccccc34)nc2C1=O +S=C(Nc1cccc(Cl)c1)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +O=C(Nc1ccc2cc(C(=O)NC3CN4CCC3CC4)sc2c1)Nc1c(F)cccc1F +COc1ccc(-c2cnc(C3C(c4ccc(Cl)cc4)CC4CCC3N4C)s2)cc1OC +O=C(CCN1CCC(c2nc(-c3cnccn3)no2)CC1)N1CCCC1c1nc2cc(Cl)c(Cl)cc2[nH]1 +CN1CCN(C(=O)c2cc3cc(Cl)cc(N)c3[nH]2)CC1 +N#Cc1ccc(-c2nc(NCCNc3ccc([N+](=O)[O-])cn3)ncc2-n2cncn2)cc1 +CN1CCN(CCn2ccc3c(N4CCOCC4)nc(-c4ccc(NC(=O)Nc5ccncc5)cc4)nc32)CC1 +CNCc1ccc(-n2cc3cc(F)cc(C(N)=O)c3n2)cc1F +O=C(NCCCN1CCC(c2noc3cc(Cl)ccc23)CC1)c1nsc2ccccc12 +O=c1[nH]nc2cc(CNC3CCCNC3)c3ccc(-c4ccc[nH]4)cc3n12 +CC(=O)c1cccc(-c2ccc3oc(CCN4CCCC4C)cc3c2)c1 +CCCCC(N)C(=O)Nc1cc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)O)ccc1N +O=C(O)c1ccc(O)c(C=NNC(=S)NC2CCCCC2)c1 +O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1cc2ccccc2s1 +O=C(O)COc1cccc(CC2CCCCC2c2nc(-c3ccccc3)c(-c3ccccc3)o2)c1 +Cc1nc(C)c(CNc2nc(OCC3CC3c3cc4ccccn4n3)nc(Cl)c2C)s1 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(Nc4ccc(N5CCNCC5)cc4)nc23)N1 +CC(=NNC(N)=O)c1cnc2nnn(Cc3ccc4ncccc4c3)c2n1 +COc1ccc2c(c1)c(CC(C)C(=O)O)c(C)n2Cc1ccc(Br)cc1 +CCOc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cc1F +O=C(O)CCC1CCc2cc(-c3cc(OC4CCC4)ncc3F)ccc2O1 +Cc1nn(C)c(C)c1N(C)S(=O)(=O)c1c(Cl)cc(CCCCCCn2ccnc2)cc1Cl +O=C1NCC(c2ccsc2)CCC1NC(=O)N1CCC(n2c(=O)[nH]c3ncccc32)CC1 +NS(=O)(=O)c1ccc(CCn2c(=O)c3ccccc3c3ccccc3c2=O)cc1 +Cn1c(-c2ccc3ccccc3c2)nnc1-c1ccccc1C(F)(F)F +CC1CCCCC1Oc1nc(N)c2c(=O)ccn(C3COCC3O)c2n1 +COC(=O)c1c(-c2c(Cl)cccc2Cl)noc1NC(=O)NN1CCCCC1 +CCCC1CN2C(=N1)N(CC)C(=O)c1nc(Cc3ccccc3)n(Cc3ccccc3)c12 +CN(C)Cc1ccn2c(-c3ccnc(NCC(C)(C)C)n3)c(-c3ccc(F)cc3)nc2c1 +NC1=NCN=C2C1N=CN2C1OC(CSCCF)C(O)C1O +CCc1c(C(C)c2c(F)cccc2Cl)nc(SC(C)CC)[nH]c1=O +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC(C)c1ccncc1)CC2 +CCN(Cc1ccc(C(=O)O)cc1)C(=O)c1ccc(Oc2ccccc2Cl)cc1 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+O=C(OCc1ccccc1F)N1CCC(CNc2ncccn2)CC1 +CN1CCC(CNC(=O)c2cc(Cl)cc(Cl)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +Cc1noc(C(=Cc2cccc(-c3cc(C(C)C)cc4cccnc34)c2)c2ccc(S(C)(=O)=O)cc2)n1 +CNC(=O)OCc1c(COC(=O)NC)c(-c2ccc(OC)c(OC)c2)n2c1Cc1ccccc1-2 +O=C(Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)cc1)c1cccc(F)c1 +CNc1nc(Nc2cc(F)c(C(=O)N3CCOCC3)cc2OC)ncc1C(F)(F)F +COC(=O)c1sc2cc(C)ccc2c1Nc1cc(OC)c(OC)c(OC)c1 +CC(F)(F)c1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc(NC(=O)C4CC4)c3)c(F)c2)c1 +COc1ccc(COc2ccc3c(c2)OCC3CC(=O)O)cc1-c1c(C)cccc1C +CN(C)C(=O)n1cnc(S(=O)(=O)C2CC3CCC2C3)n1 +c1ccc2nc(CCCCN3CCc4c([nH]c5ccccc45)C3)ccc2c1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1COc3ccccc31)CC2 +CN1CCN(Cc2cccc(C(=O)NCc3cccc(-c4cccc(CN5CCNCC5)c4)c3)c2)CC1 +O=C(O)c1ccc(N2CC3(CCN(Cc4nc(-c5ccccc5)oc4-c4ccccc4)CC3)OC2=O)cc1 +COc1ccc(-n2nnc(-c3ccccc3NC(=O)c3cccc([N+](=O)[O-])c3)n2)cc1 +CN(C)c1ccc(C(=O)NC(CCCCCC(=O)NO)C(=O)Nc2cccc3cccnc23)cc1 +COc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(C)CCCc3ccccc31)CC2 +c1ccc(-c2cc(NCc3cccnc3)n3ncc(C4CC4)c3n2)cc1 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+CN1CCc2cc(N)cc3c2C1Cc1ccc(O)c(O)c1-3 +CC(=O)N1c2ccc(NC(=O)c3ccc(-c4ccccc4)cc3)cc2C(C)(c2ccc(C)cc2)CC1(C)C +COc1ccc(NC(=O)CN(C)C(=O)C2=COCCO2)cc1 +CN(C)CCCCOC(=O)Nc1cccc(Cn2nc(-n3ccc4ccc(F)cc43)ccc2=O)c1 +CC(C)(C)OC(=O)NC(CSCCC(=O)NCc1cccnc1)Cc1c[nH]c2ccccc12 +COC(=O)C1=C(CN2CCOCC2)NC(c2ccccn2)=NC1c1ccc(F)cc1Cl +Cc1ccc(NC2=C(Cl)C(=O)c3nc(C)[nH]c3C2=O)cc1 +OCc1ccc(Oc2cccc(-c3c(-c4ccccc4)cnc4c(Cl)cccc34)c2)cc1 +CC(C)(C)c1ccc(C(=O)NC(=S)Nc2ccc(NC(=O)c3ccccc3)cc2)cc1 +CN(C)C1Cc2ccccc2C(c2cccc(-c3ccccc3)c2)C1 +Cc1ccc(S(=O)(=O)N2CCN(c3ncccc3C#N)CC2)cc1 +NS(=O)(=O)c1ccc(NNC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +COc1cccc(F)c1-c1cccc2nc(NC3CCCCC3)oc12 +O=C1NCN(c2ccccc2)C12CCN(C1CCc3ccccc31)CC2 +CC1(C)CCC(C)(C)c2cc(C(=O)Nc3cc(F)c(C(=O)O)c(F)c3)c(O)cc21 +COc1cccc(OC)c1-c1ccc(CC(NC(=O)C2(c3cccc([N+](=O)[O-])c3)CCCO2)C(=O)O)cc1 +CC(C)(C)OC(=O)NCC1CCC(CNC(=O)c2cc(-c3ccccc3)nc3[nH]ccc23)CC1 +NC(=O)c1ccc2[nH]c(-c3ccc(OCC4CCN(Cc5ccc(Cl)c(Cl)c5)CC4)cc3)nc2c1 +COc1ccc(Nc2cc(-c3cccc(C(=O)Nc4ccc(C(=O)O)cc4)c3)nn3ccnc23)nc1OC +COc1ccc(C2CC(=O)N2c2cc(OC)c(OC)c(OC)c2)cc1 +CNc1cccc(CCOc2ccc3c(ccn3CCC(=O)O)c2)n1 +COc1cc(-c2nc(C(F)(F)F)cn2-c2ccc(S(C)(=O)=O)cc2)ccc1Cl +O=C(CCCN1CCN(c2ccc(F)cc2)CC1)NC1c2ccccc2Oc2ccccc21 +CC12CCC3C4(C)CCCC(C)(C(=O)O)C4CC(O)C3(CC1=O)C2 +CN1CCC(OC(c2ccccc2)c2ccc(Cl)cc2)CC1 +CCc1ncnc(-c2ccc(N(C)C)nc2)c1C#Cc1ccc(N)nc1 +COc1ccc(C(F)Cn2ccnc2O)cc1OC1Cc2ccccc2C1 +Cc1cccc(C(=O)N2c3ccccc3C(=O)OC2c2ccc3c(c2)OCO3)c1 +CCc1nc(C)cn1-c1ccc2nc(O)c3c(C)nc(CC)n3c2c1 +CCOC(=O)N1CCC(N2CCCC(NC(=O)c3ccccc3)C2)CC1 +Cc1c(Cn2cc(C(=O)NCCF)c3ncccc32)ncnc1N(C)C +CN(CCNC1CCNc2c(Cl)cc(Cl)cc21)c1nc2nc(Cl)ccc2[nH]1 +CN1CCN(c2ccc(NC=C3C(=O)NC(=O)c4ccc(-c5ccoc5)cc43)cc2F)CC1 +COCCOc1cc2nc(-c3ccccc3O)nc(NC3CCNC3)c2cc1OC +COc1ccccc1CC(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3Cl)nn2)s1 +Cn1cc(C2=C(c3cnc4ccccn34)C(=O)NC2=O)c2cc3c(cc21)OCO3 +CCCCCCN1CCC(c2ccn3c(-c4ccnc(N)n4)c(-c4ccc(F)cc4)nc3c2)CC1 +NC(CC(=O)N1C(C(=O)NCC2CC2)CC2CCCCC21)Cc1cc(F)c(F)cc1F +COc1ccc(-c2sc3c(c2CN(C)Cc2ccccc2)c(=O)n(-c2ccccc2)c(=O)n3Cc2c(F)cccc2F)cc1 +Cc1c(-c2nnn(C(C)C)n2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(NC1(C(=O)NC(Cc2ccccc2)C(=O)NCCCNC2CCOCC2)CCCC1)c1cc2ccccc2s1 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)Nc1cnc(N2CCOCC2)nc1 +Nc1nc(N)c(SCCc2ccc(C(=O)NC(CCC(=O)O)C(=O)O)cc2)c(O)n1 +COC(=O)c1ccc(C(=O)CN2C(C(=O)c3ccccc3)=C(O)c3ccccc3S2(=O)=O)cc1 +COc1cccc(C=NN(C(=O)C(F)(F)F)c2ccc(CO)cc2C)c1 +CCOn1cc(C2=NC(c3ccc(F)cc3)(c3ccc(F)nc3)C(C)N2)ccc1=O +CCn1c(=O)ccc2cnc(Nc3ccc(N4CCCCC4)cc3)nc21 +CCc1sc(C(=O)CCc2cc(C)c(OCC(O)CO)c(C)c2)c2c1CC(C)(O)CC2 +CC(C)CS(=O)(=O)N1CCCC(Nc2ncccc2-c2cnc3[nH]ccc3n2)C1 +COc1nc2c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c(F)cnc2cc1F +CCN(CC)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc3c(c2)OCCN3)c(F)c1 +Cn1cc(-c2ccccc2)nc1SCc1cn2c(Cl)cccc2n1 +O=C(Nc1ccc(COC2CCNC2)cc1)c1ccc(Cl)cc1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CN)c4ccccc4)ncc23)ccn1 +COc1nn2cc(-c3cc4c(OCc5cccc(OCc6ccccc6)c5)cc(OC)c(Cl)c4o3)nc2s1 +CC(C=CC(=O)NO)=CC(C)C(=O)c1ccc(N(C)C)cc1 +Nc1ncc2ccc(Cl)cc2c1C#Cc1ccc(C2=NC(C3CC3)CN2)cc1 +CC1(CCCCN2CCSCC2)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1 +O=C(O)C(Cc1ccc(I)cc1)NC(=O)C1CCCN1S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CC(C)c1nnn(-c2c(Cl)cccc2Cl)c1COc1ccc(C=Cc2cccc(C(=O)O)c2)c(Cl)c1 +O=C(c1ccc(O)cc1O)N(Cc1ccsc1)c1ccc(-c2ncnc3cccc(F)c23)cc1 +CS(=O)(=O)Nc1ccc(-c2cnccc2C2CC2)c(C(F)(F)F)c1 +O=C1N(c2ccc(C3CCC(N4CCC4)CC3)cc2F)CCC12CCNCC2 +C1=C[N+]2=C(C1c1cccc3ccccc13)C1c3ccccc3C2CC1(c1ccoc1)c1ccoc1 +CCCC(C)n1c(CC)nc2c(-c3ccc(OC)cc3C(F)(F)F)ccnc21 +CC1(C)CCCC2(C)c3c(oc4c(C(N)=O)c(O)c(O)cc34)CCC12 +CC(c1nc2c(cnn2C2CCOCC2)c(=O)[nH]1)N1CC(Oc2ccc(F)c(C#N)c2)C1 +COC(=O)c1cc(NC(=O)C(C)(C)Cc2ccc(C(=O)Oc3ccc(C(=N)N)cc3F)s2)cc(C(=O)OC)c1 +CCC(CC)(Cc1nc2cc(OCc3nc4ccccc4s3)ccc2n1Cc1ccc(Br)cc1)C(=O)O +Cc1nc2nc(-c3ccc(CN4CC(c5n[nH]c(-c6ccccn6)n5)C4)cc3)c(-c3ccccc3)c(C)n2n1 +Cc1cc(C)c(C(=O)n2nc(Nc3ccc(S(N)(=O)=O)cc3)nc2N)s1 +Nc1ncc(-c2ncccc2C(F)(F)F)nc1C(=O)Nc1ncccc1N1CCC(N)(CCO)CC1 +CCCc1cc2c(=O)n(C(C)C)oc2c(CCC)c1OC(C(=O)O)c1ccc(C(C)C)cc1 +O=S(=O)(c1ccccc1)C1(F)CCN(CCc2ccc(F)cc2F)CC1 +CCc1ncnc(-c2ccc(C(=O)N3CCOCC3)c(F)c2)c1C#Cc1ccc(N)nc1 +CCCOc1ccc(Oc2ccc(-c3ccc(C(C)NC(=O)COC)cc3)cc2)cc1 +CCCCCC(=O)Nc1ccc(C(=O)Nc2cccc(CC(C)C(=O)O)c2)cc1 +CN(Cc1ccccc1)C(=O)C(Cc1ccc2ccccc2c1)NC(=O)C1CCCN1C(S)=NCc1ccccc1Cl +COc1cccc(-c2cc(C(=O)Nc3cc4ccc5c(c4oc3=O)NC(=O)C(CCNC3CCCCC3)O5)ccc2OC)c1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3c(CNC4CC4)c(O)ccc3nc2-1 +COc1ccc2c3c1OC1C(OC)C(C)CC4C(C2)N(C)CCC341 +O=c1cc(-c2cccc([N+](=O)[O-])c2)[nH]c2c(-c3cccs3)c(C(F)(F)F)nn12 +Cc1c(S(=O)(=O)NCc2cnc(Oc3ccc4c(c3)CCC(c3ccccc3)O4)s2)cnn1C(C)C +NC1(c2ccc(-c3nn4c(-c5ccc(F)cc5)c(Cl)nc4cc3-c3ccccc3)cc2)CCC1 +O=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1ccccc1-n1nccn1 +COC(=O)c1c(F)cccc1-c1ccc(C(C)NC(=O)C2(NC(=O)CC(F)(F)F)CC2)c(F)c1 +COC1CCC(C)N(c2nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +Clc1cccc(N2CCN(CCCCOc3cc4ccccc4cn3)CC2)c1Cl +Cc1cc(CNC(=O)c2ccc(N3CCC(Oc4ccccc4Cl)CC3)nn2)on1 +CCc1cc(-c2noc(-c3cc(OC)cc(CC(C)C)n3)n2)cc(C)c1OCC(O)CNC(=O)CO +CC(C)(C)NC(=O)NCCCc1nc2cc(S(=O)(=O)NCc3ccc(F)cc3)ccc2n1Cc1ccccc1 +Cc1ncn(-c2nccc3c(S(=O)(=O)N4CCN(C(=O)c5ccccc5)CC4C)c[nH]c23)n1 +Cc1cc(C)nc(SCC(=O)Nc2ncc(Cc3cccc4ccc(Br)cc34)s2)n1 +CC(=O)N1CCN(C(=O)c2cc3c(s2)CCN(c2cccc(-c4nc5ccccc5n4C)c2)C3)CC1 +CN(C)CC1(c2ccc(-c3c(O)ccc4[nH]c(=O)c5sccc5c34)cc2)CC1 +Oc1nc2c(c3nc(-c4ccccc4F)cn13)CN(Cc1cccs1)CC2 +Cc1nc(N2CCC(N3CCCC3C)C2)ccc1NC(=O)Cc1ccccc1 +Cc1c(C(=O)Nc2c(C)n(C)n(C3CCCCC3)c2=O)nnn1-c1ccc(C2CC2)cc1Cl +CCCCn1nc(C(C)(C)C)sc1=NC(=O)c1cc(C(F)(F)F)ccc1ON=C1CCCCCN1 +COc1cc(-c2cccc(OC(C)C)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3cccnn3)ccc21 +Cc1nc(N2CC(c3nc4ccccc4n3C)C2)cc(-n2nc(C(F)(F)F)nc2C)n1 +O=C(NC1CCCCC1O)c1cnc(OCC2CC2)c(-c2ccc(Cl)cc2)c1 +CC(=O)N1CCc2c(c(-c3ccc(Cl)c(C)c3)nn2CC(O)CN2CCC(n3c(O)nc4ccc(Cl)cc43)CC2)C1 +Cc1nc2ccc(-n3cnc4cnc5cnc(-c6ccccc6)cc5c43)cc2s1 +Nc1cccnc1C(=O)Nc1ccc(N2C(=O)c3ccccc3C2=O)c(Cl)c1 +CC1(C)CCN(c2ccc(C#Cc3cc(F)ccc3F)cn2)C(=O)O1 +C#CCN(c1ccc(C#N)cn1)C1CCN(c2ncnc3[nH]ccc23)C1 +Cc1cccc(-c2cc(N(CCCN3CCCCCC3)Cc3ccc4c(c3)OCO4)on2)c1 +Cc1ccc(C#N)cc1C#Cc1ccc(CCC(=O)O)cc1 +COC12C(COC(N)=O)c3c(O)c(N=C4C=CC(=O)C(I)=C4)c(C)c(O)c3N1CC1NC12 +CC(=O)c1ccc(-c2sc(N)nc2-c2ccc(P(=O)(O)O)o2)cc1 +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ccccc2)CC1 +O=C(CCc1ccc(Br)cc1)NC=CNCCOC(c1ccc(F)cc1)c1ccc(F)cc1 +CC(F)(F)C(=O)Nc1ccc(F)c(C2(C)CS(=O)(=O)C3(CCOC3)C(=N)N2)c1 +CCc1ccc2ncc(C(=O)OCC(C)CC)c(O)c2c1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)C4CCC(C)N4CC(C)C)ncn3)cccc2s1 +COCCN(C)c1ncc2ncnc(Nc3cc(C(=O)Nc4cc(C(C)(C)C)on4)ccc3F)c2n1 +OC1CCC(Nc2cc(-c3cncc(NCC4CCCOC4)n3)c(Cl)cn2)CC1 +CN1CCN(c2nc(-c3ccccc3)c(-c3nc4ccccc4c(=O)n3-c3ccccc3[N+](=O)[O-])s2)CC1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(Cc3cc(F)cc(F)c3)CC2)C1 +COc1c(Br)cc(Br)cc1CNC1CCCN(c2nc3nc(Cl)ccc3[nH]2)C1 +O=C(c1c[nH]c2cc(F)ccc12)C1CSC(c2cccnc2)N1 +Cn1ncc2ccc(-c3cc(COCC(O)CN4CCc5ccccc5C4)on3)cc21 +CCN(CC)C(=O)c1ccc(-c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)cc1 +CNC(=O)CN1Cc2ccccc2N(C2CCN(C3CCCCCCCCC3)CC2)S1(=O)=O +O=S(=O)(Nc1nccs1)c1ccc(NC(=S)Nc2ccc3ncnc(Nc4cccc(Br)c4)c3c2)cc1 +Cc1nc(N(C)C)ccc1N1CCc2c(-n3ccc(-c4nccs4)n3)ccnc21 +COc1ccccc1N1CCN(c2ncnc3c2cnn3-c2cccc(C)c2)CC1 +CN1C(=O)C(NC(=O)Nc2cccc(Br)c2)N=C(c2ccccc2)c2ccccc21 +Cc1ccc(-c2nc(C)c(C(=O)NC3CCCN(c4cccc(C(=O)O)c4)C3)s2)cc1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)c1nnn2c1nc(NCc1cccs1)c1sccc12 +C#CCOC(=O)c1ccc(N2CCN(S(=O)(=O)c3ccccc3N3CCC(O)CC3)CC2)nn1 +O=C(c1cccs1)c1no[n+]([O-])c1C(=O)c1cccs1 +CC1=NN(C)C2C(=O)N(c3ccc(=O)n(C)c3)C(c3ccc(Cl)cc3)C12 +COc1cc(C(=O)Nc2cc(C3CC3)ccn2)ccc1-c1nc(C2CCC3C(C)OC(=O)N3C2)n2ccnc(N)c12 +NS(=O)(=O)c1ccc(-c2cn(-c3cccc(Br)c3)nn2)s1 +CS(=O)(=O)c1ccc(Nc2nn(C3(CC#N)CCCCC3)cc2C(N)=O)cc1 +COC1CCC2(CC1)Cc1ccc(C#N)cc1C21N=C(C)C(N)=N1 +O=C(Nc1ccc(Cl)c(Cl)c1)c1ccc2cn[nH]c2c1 +CC(C)OCC#Cc1cc2c(cc1N1CCN(C3COC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +CNCCn1c(=O)n(C2CCN(CCC(Oc3cc(OC)ccc3C)C(C)C)CC2)c2ccccc21 +Cn1c(-c2ccc(-n3ccnc3)cc2)nnc1C1(c2ccc(Cl)cc2)CCC1 +COc1ncnc(Nc2ccc(Cl)c(OCC=C(C)C)c2)n1 +CC(C)CN1CCC23c4c5ccc(O)c4OC2c2[nH]c4ccccc4c2CC3(O)C1C5 +CC1=CC(C)(C)Nc2cc3c(cc21)-c1ccc(F)cc1C3O +CCC(C)C(NC(=O)C(CC(C)C)C(C(C)C)N(O)C=O)C(=O)Nc1ccccn1 +C#CCn1nc(-c2ccc3ccccc3c2)c2c(N)ncnc21 +CS(=O)(=O)N1CCN(C2CCC(Nc3ncnc4ccc(C#N)cc34)CC2)CC1 +COc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3ccnn3)c1)=N2 +Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3Cn3cccc(C(F)(F)F)c3=O)c2n1 +COc1ccc(C=Cc2cc(OC)c(OC)c(OC)c2)c(N)c1N +CCN(C(=O)c1ccc(F)cc1)C1CCN(C(C)CC(NC(=O)C2CCC2)c2ccccc2)CC1 +CC1CC(=O)NN=C1c1ccc2nc(-c3ccsc3)oc2c1 +Cc1ccc(N(C(=O)c2cc(F)cc(F)c2)C(=S)OCCN2C(=O)c3ccccc3C2=O)cc1 +C(=Cc1ccccc1)CN1CCN(C(c2ccccc2)c2ccccc2)CC1 +CC1OC(=O)C2CC3CC(F)(F)CCC3C(C=Cc3ccc(-c4ccccc4Cl)cn3)C12 +CC(=O)NC(Cc1ccc(OP(=O)(O)O)cc1)C(=O)NC1CSCCN(Cc2cccc(-c3ccccc3C#N)c2)C1=O +CC1(O)CCN(c2cccc(C(=O)NC3C4CC5CC3CC(O)(C5)C4)n2)CC1 +CCC(CC)C(=O)Oc1cn(-c2ccccc2)c(CSc2nc3ccccc3s2)cc1=O +O=C1N=C(Nc2ccccc2)N=C2C1N=CN2C1CC(O)C(CO)O1 +CCOc1cccc(NC(=O)C2Cc3cc(OC)c(OC)cc3C2=O)c1 +COc1ncc(-c2nc3c(n2C(C)C)C(c2ccc(Cl)cc2)N(c2cc(Cl)cnc2O)C3=O)c(OC)n1 +CN(C(=O)Oc1ccc(F)cc1)C1(C)CN(C(=O)C2CCN(C(=O)C3(C)CC3)CC2)CC1c1ccc(Cl)cc1 +N#Cc1cnc(-c2nc(CC(=O)N3CCC3)cs2)c(O)c1 +COC1COC2C(OC(=O)NC(Cc3ccccc3)C(O)CN(CC(C)C)S(=O)(=O)c3ccc(N)cc3)COC12 +CC(=O)NC(C)c1ccc(C2CN(c3ccc4c(c3)OCCO4)C2)cc1 +Cc1c(-c2ccccc2F)c(=O)n(CC(N)c2ccccc2)c(=O)n1C1CCCCC1 +COc1cc(-c2cnc3nc(N4CCC(N5CCCCC5)CC4)oc3c2)ccn1 +CN1CCN(CCCNc2ccc(-c3cc4ncn(C)c(=O)c4c(NC4CC4)n3)cc2S(C)(=O)=O)CC1 +COc1cc(-c2cnn(CCN(C)C)c2)ccc1Nc1ncc2ccnc(NC3CCCCC3)c2n1 +COc1ccc(-n2c(C)nnc2N2CCC(Oc3ccc(F)cc3C)C2)cn1 +CCN(CC)CCNC(=O)c1ccc(Nc2ncc(C)c(Nc3cc(C4CC4)n[nH]3)n2)cc1 +CN(CCO)Cc1ccc(-c2ccc(NS(=O)(=O)c3cccc4cccnc34)cc2)cc1 +Cc1cc(OCc2ccc(Cl)c(Cl)c2)ccc1CN1CC(C(=O)O)C1 +CN1CCCC1CCN1CCOc2cc(N=C(N)c3cccs3)ccc21 +O=C(CC1(N2CCOCC2)CCCCC1)Nc1ccc2[nH]nc(-c3ccc(N4CCOCC4)cc3)c2c1 +COc1ccc(N2CCN(CCCOc3ccc(=O)n(-c4ccc(Cl)c(Cl)c4)n3)CC2)cc1 +O=C(CCCCCCCCc1ccccc1)c1nnc(-c2ccccn2)o1 +CCN(CC)Cc1cc(F)ccc1C=C1Oc2ccc(O)c(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +CCNC1=NC(=Cc2ccc(-n3cnc(C)c3)c(OC)c2)C(=O)N1Cc1ccc(F)cc1 +CC12CCC3C(=CCc4cc(O)ccc43)C1CCC2=O +CC(C)(C)C(NC(=O)OC1CCCC1)C(=O)N1CC(Oc2nccc3ccccc23)CC1C(=O)NC1CCCOB1O +CCCn1c(=O)c2[nH]c(-c3ccc(N)cc3)cc2n(CCC)c1=O +COc1ccc(S(=O)(=O)N(CCn2cccc2)C(Cc2cccs2)C(=O)NO)cc1 +CCCS(=O)(=O)Nc1ccc(F)c(C(=O)Nc2cnc3[nH]c(-c4ccc(Cl)c(Cl)c4)nc3c2)c1F +COc1cc2c(cc1OC)C(=O)C(C(=O)Nc1ccc(Cl)cc1)C2 +O=C(O)CCc1sc(C=C2NC(=O)CS2)nc1-c1ccccc1 +O=C(O)C(Cc1ccc2c(c1)oc1ccccc12)NC(CCc1cccc2ccccc12)P(=O)(O)O +O=S(=O)(c1cccc2ccccc12)N(CCCN1CCN(c2ccccc2)CC1)CC1CC1 +CC(NC(=O)c1nn(-c2ccc(Cl)cc2Cl)c2c1CN(C(=O)CC(N)=O)CC2=Cc1ccc(F)cc1)c1ccccn1 +CCCCc1nc(SCCCCO)c(C(=O)O)n1Cc1ccc(-c2ccccc2S(=O)(=O)NC(=O)NCCC)cc1 +COc1ccc2nccc(NC(=O)C3CCC(NCc4cc5c(cn4)OCCO5)CO3)c2n1 +CS(=O)(=O)c1ccc(-c2cnc3ccc(-c4cccc(C(=O)NCCO)c4)nn23)cc1 +N=C(N)NCCCC1NC(CNC(=O)C2CCc3ccccc3C2)CCN(CC(c2ccccc2)c2ccccc2)C1=O +Cn1cc(C(=O)OCC2CN(Cc3ccc(Cl)cc3)c3cn(CCc4ccccc4)nc3C(=O)N2)c2ccccc21 +CC(C(=O)OC1C[N+]2(CCCc3ccccc3)CCC1CC2)(c1ccccc1)N1CCCCC1 +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CCCC(C)(C)O)CC(O)C(CCn2ncnn2)C1O +CN1CC=C(c2c[nH]c3ccc(-c4cccs4)cc23)CC1 +CNC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1S)CC(C)C +Cc1cc(S(C)(=O)=O)cc2c(Nc3cccc(C#N)c3)c(C(N)=O)cnc12 +Cc1ccc2nc3ccc(N4CCCC4)nn3c(=O)c2c1 +Cc1cccc(N2CCN(CCCCCCN3CCN(c4ccccc4)CC3)CC2)n1 +CC(CNC(=O)c1cc(Cl)cc(Cl)c1)CNc1nc2ccccc2[nH]1 +CCCCN(c1cccc(-c2ccc(Cl)cc2)c1C)S(=O)(=O)c1ccc(OC(CCC)C(=O)O)c(C)c1C +CCN(CC)CCNC(=O)C=Cc1cnc(N)c2c(-c3ccc(NC(=O)Nc4cccc(C)c4)cc3)csc12 +Cc1c(C(=O)Nc2ccc(C3CNCCO3)cc2)n[nH]c1-c1cccc(C#N)c1 +CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2(C#N)C3CC4CC(C3)CC2C4)cc1F +CCCC(NC(CC(C)C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)O)P(=O)(O)O +CC(=O)N(Cc1ccc(F)cc1)C1=C(NCc2ccccc2)C(=O)c2ccccc2C1=O +O=C(Nc1ccc(CCNCC(O)c2cccnc2)cc1)c1cccc(CCn2cccc2)c1 +c1cnc(C2CN(c3nnc(N4CCC(N5CCCCC5)CC4)s3)CCO2)cn1 +Cc1ccccc1Nc1cc[nH]c(=O)c1C(=O)Nc1ccc(N2CCN(C)CC2)cc1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccccc1 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+O=C(Nc1ccc(Br)cc1)N1CCN(CC2CCCN(C3CC3)C2)CC1 +COc1ccccc1N1CCN(CCNC(=O)C2CCCCC2)CC1 +Cc1c(O)cccc1C(=O)NC(Cc1ccccc1)C(O)C(=O)N1CSC(C)(C)C1C(=O)NC1CCCC1 +CC1Cc2nc(NCC(F)F)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2CN1C +CC(C=CCN1CCCC(CCC2CCNCC2)C1=O)CC(=O)O +Cc1nn(C(=O)C=Cc2cccc(C(F)(F)F)c2)c2c1C1C(C2)C1(C)C +C=CCN(C(=O)OCc1ccc(F)cc1)C1CCN(CC2CN(C(=O)C3CCCC3)CC2(O)c2ccccc2)CC1 +CN1CC(n2nccc2-c2cc(C(F)(F)F)ccc2-c2cccc3cc(S(=O)(=O)Nc4nccs4)ccc23)C1 +Cc1cc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cc5ccccc5F)C4)cc23)ccn1 +CC(C)(C)c1ccc(S(=O)(=O)Nc2ccc(Cl)c3c2C(=O)N(c2cccnc2)C3=O)cc1 +CCNC(=O)c1cccc(-n2ccc3cnc(Nc4cc(OC)c(OC)c(OC)c4)nc32)c1 +O=C(O)Cc1nn(Cc2nc3cc(F)cc(Cl)c3s2)c(=O)c2ccccc12 +Nc1ccncc1-c1cc(F)cc(-n2nnc(-c3ccccn3)n2)c1 +C[N+](C)(C)CC1CSC(C2CCCCC2)(C2CCCCC2)O1 +N#Cc1ccc(F)c([S+]([O-])c2nc(-c3cnn4ccc(Br)cc34)cs2)c1 +Cc1ccc(-c2cn(C)c(CCc3nc4c(F)cccn4n3)n2)o1 +NC1=NC2(CCS1)c1cc(NC(=O)c3ccc(F)cn3)ccc1Oc1c2cc(-c2ccnc(F)c2)nc1F +O=C(NC(CC1CCCCC1)C(=O)NCCNc1ccc(OC(F)(F)F)cc1)c1ccc(-c2cccc(C(F)(F)F)c2)o1 +CCN1CC(C)(C)Oc2nc(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)NC)cc3F)c2C1=O +O=C(NC1CCCCC1O)C1Cc2c(sc3ccccc23)CN1 +Nc1n[nH]c2cc(-c3ccc(NS(=O)(=O)c4cc(F)ccc4F)cc3)ccc12 +COc1ccc(-c2nncn2-c2cc(OC)c(OC)c(OC)c2)cc1N +CN1C(=O)NC(=O)C12Cc1cc3nc(Cn4c(=O)n(-c5ccccn5)c5ccccc54)[nH]c3cc1C2 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3cc(Br)ccc23)c2ccccc2OC12CCNC2 +Cc1nc2cc(F)c(Cn3c(C(=O)O)c(-c4ccc[nH]c4=O)c4c5occc5c(F)cc43)cc2c(=O)[nH]1 +NC(=O)C(=O)C(Cc1ccccc1)NC(=O)c1cccnc1N1CCC(c2ccccc2)C1 +O=C(Cc1ccc2c(c1)OCO2)NC1CCC(CCN2CCN(c3nccc4c3CCO4)CC2)CC1 +Cn1cc(-c2ccccc2Oc2ccccc2)c2cc(-c3ccccc3)[nH]c2c1=O +COCCOc1nc(C2CC2c2nc3ccccc3n2C)cc(-n2nc(C)nc2C)n1 +CCOc1ccc(S(=O)(=O)N(CC(=O)N2Cc3ccccc3CC2CC(N)=O)c2ccc(C)cc2)cc1 +N=C(N)C1(C(=O)Nc2ccc(CCCCCCOCC3CCCCC3)cc2)CC1 +NC1=NC(=O)C2CCCN2c2ccc(cc2)OCC=CCNCC(=O)Nc2c(Cl)cc(cc2Cl)CN1 +CCCCC(=O)NCC1C(C(=O)Nc2ccc(Br)cc2)C2C=CC1C21CC1 +CN(C)CCOc1ccc(-c2cccc(N)n2)c2c1CCC2 +Cn1cnc2c(-c3ccc(OCCC4CCN(CC#N)CC4)c(C(F)(F)F)c3)nc(C#N)nc21 +O=C1NCc2ccc(OCCCCN3CCN(c4cccc5ccc(F)cc45)CC3)c(F)c21 +CCC(C(=O)OCC1(CO)CC(=Cc2ccccc2C(F)(F)F)C(=O)O1)c1ccccc1 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)Nc3ccc(N)cc3)CCC12 +CC1(C)C2CCC(NC(=O)c3cc(Oc4c(Cl)cc(-n5ncc(=O)[nH]c5=O)cc4Cl)ccc3O)C1C2 +Cc1cc2nc(-c3ccc(-n4nc5c(c4C)N(C)S(=O)(=O)c4ccccc4-5)cc3)[nH]c2cc1C +CC(=O)Nc1ccc(-c2nc(Nc3ccc(N4CCOCC4)cc3)ncc2C)cc1 +CCOC(=O)c1nn2c(=O)[nH]c3cc(Cl)c(NC(=O)c4ccccc4C(=O)O)cc3c2c1C(=O)OCC +COc1ccc2c(c1)C1(CC(N)=O)CCN(CC3CC3)C(C2)C1CO +COc1ccc(C(=O)NN=C(C)C(=NNc2ccc(S(N)(=O)=O)cc2)S(=O)(=O)c2ccccc2)cc1 +CC(O)c1cc2cnc(Nc3cc(C(=O)N4CCN(C)CC4)n(C)c3)nc2n1C1CCCC1 +CN1CCN(Cc2ccc(C(=O)NN(Cc3ccco3)c3nc(C#N)ncc3Br)cc2)CC1 +O=C1CCN(C(=O)CCSc2ccc([N+](=O)[O-])c3nonc23)CC1 +COC1=CC(=O)c2c(c(COC(N)=O)c(C)n2C)C1=O +Cc1nc2ccccc2c(Nc2ccc(N3CCN4CCCCC4C3)cc2)c1C +O=C(O)C(Cc1ccccc1)NC(=O)C1CCC(=O)N1Cc1ccccc1 +Cc1cc(-c2cccc3ncc(-c4ccc(C(=O)N5CCOCC5)c(C)c4)nc23)ccc1CN1CCOCC1 +O=S(=O)(c1ccc(Cl)cc1)C1(c2cc(F)ccc2F)CCCC(CCCO)C1 +C=C(c1ccc2c(c1)C(C)(C)CCC2(C)C)c1ccc2cc(C(=O)O)ccc2c1 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+CC1=C2NCC3C(CCC4(C)C(C(=O)Nc5c(C(C)(C)C)cccc5C(F)(F)F)CCC34)C2(C)CCC1=O +COc1ccc(Br)cc1CCc1c(Cl)cccc1C(=O)N=C(N)N +NC(CC(=O)NC1(c2nc3c(Cl)cccc3s2)CCS(=O)(=O)CC1)Cc1ccccc1F +O=C(c1ccc(Cl)cc1)N(c1ccccc1)C1CCN(Cc2ccccc2)CC1 +O=C(O)c1ccccc1-c1ccc(Cn2c(C3CC3)nc3c(CO)ccnc32)cc1 +COc1ccc(-c2cnc3c(-c4cccnc4)cnn3c2)cc1 +O=C1CCc2cc(C(c3ccncc3)C3CCCCC3)cc3c2N1CC3 +CC1(c2cccc(-c3cncnc3)c2)N=C(N)c2ccccc2S1 +O=C1NC(=O)C(c2cc(Cl)ccc2S(=O)(=O)NCCCc2ccccc2)N1 +Cc1ccc(-c2c(C(=O)CCl)n(CCCO)c3ncnc(N)c23)cc1 +CC(C)(C)COP(=O)(CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)OCC(C)(C)C +Nc1n[nH]c2cc(-c3ccc(NC(=O)Nc4cccc(C(F)(F)F)c4)cc3)ccc12 +Cn1ncc(-c2ccc3c(c2)N(c2nc4c(s2)C(=O)NC(C)(C)C4)CCO3)c1N +CCN(C)C1CN(CC2CCC(c3nnn4cnc5[nH]ccc5c34)CC2)C1 +COc1ccc(C2(O)OC(=O)C(c3ccc4c(c3)OCO4)=C2CC2CCCCC2)cc1 +COc1ccc(OC)c(C=CC(=O)c2ccccc2-c2ccc(F)cc2)c1 +CC(c1ccc(-c2cc[nH]c(=O)c2)cc1)N1CCC(CC(C)(C)C#N)(c2ccccc2)OC1=O +NCC(c1ccccc1)N1CCN(c2ncnc(N)c2-c2ccc(F)cc2)CC1 +O=C(Nc1cccc(NC(=O)c2ccco2)c1)c1ccccc1 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+Clc1ccc(C2CC3CCC2N3CCCCCCN2C3CCC2C(c2ccc(Cl)nc2)C3)cn1 +CN1CCCC1c1ccc(C(O)(c2ccccc2)c2ccccc2)o1 +N#Cc1cc2cn(S(=O)(=O)c3cccc4ccccc34)c3cccc(o1)c23 +COc1cc(OC)cc(N(CCN(Cc2ccc(N)cc2)C(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1cc(Nc2nc(N3CCN(C(=O)Cc4ccccc4C)CC3)nn3cccc23)n[nH]1 +O=C(O)CCCCCCCOc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1 +NC(=O)c1cccnc1COc1cc(-c2ccc3c(c2)COC(=O)N3)cc2ncccc12 +CNc1nc(CC(=O)Nc2ccc(CCNCC(O)c3cccnc3)cc2)cs1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(Cl)nc1 +COc1cc(C)nc(OC(C(=O)O)C(OC)(c2ccccc2)c2ccccc2)n1 +CCCCC1CC(N(C)C(C)C)CCC1NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCC(N)C4)ncn3)c2c1 +Cc1cc(Nc2ncc(-c3nc4ccncc4s3)c(NC3CC(CO)C(O)C3O)n2)ccn1 +CN1CCN(CC=Cc2ccc3c(c2)CC2CCC(C3)C23CN(CC(F)(F)F)S(=O)(=O)N3)CC1=O +CCN1CCN(C(=O)NC(C(=O)NCB(O)O)c2ccc(O)cc2)C(=O)C1=O +Nc1ncnc2c1c(-c1ccc(F)c(O)c1)nn2C1Cc2ccccc2C1 +O=C(NCCCCO)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +CCOc1cc(C(Nc2ccc3cnccc3c2)C(=O)NS(=O)(=O)c2cccc(S(C)(=O)=O)c2)ccc1OC(C)C +C=C(Br)C(=O)Nc1cccc(C=CC(=O)Nc2cc(OC)c(OC)c(OC)c2)c1 +CCCC(C)CN1CCC(c2ccc(C(O)(CC)CC)cc2)(c2cccc(C(N)=O)c2)CC1 +Cc1cc(N=S2(=O)CCCC2)cc2ncnc(Nc3ccc(F)cc3OC(C)C(N)=O)c12 +CC1CCC(C)N1CCCOc1ccc(-c2ccc(C#N)cc2)cc1 +COc1ncc(N2CCc3ncnc(NC4CCN(C(=O)c5cn(C)cn5)C4)c3C2)cc1C +Cc1cccc(S(=O)(=O)NC(=O)NCCCCCCCCNC(=O)NS(=O)(=O)c2cccc(C)c2)c1 +CCNC(=O)Nc1ccc(CCCCNCCc2c(-c3cc(C)cc(C)c3)[nH]c3ccccc23)cc1 +COc1cc2ncc(C#N)c(Nc3ccc(Cl)c(Cl)c3)c2cc1OC +COc1c(F)cccc1C(=O)N1CCCC(Nc2nc3cc(Cl)ccc3o2)C1C +CNC(C)C(=O)NC(CCC(N)=O)C(=O)N1CCCC1C(=O)NC1CCCc2ccccc21 +O=S(=O)(c1ccccc1)N(c1ccc(O)cc1)c1ccc(OCCN2CCCCC2)cc1 +O=S(=O)(NCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1)c1ccc(Cl)cc1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2ccc(F)cc2F)c1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4cc5ccccc5cn4)CC3)CN(C)C1C2 +O=C(NS(=O)(=O)N1CCC1)c1cc(C2CC2)c(OC2C3CC4CC2CC(F)(C4)C3)cc1F +CCOC(=O)c1c(NCCNc2ccccc2)n(-c2ccccc2)c(=S)n(-c2ccccc2)c1=O +CCn1c(-c2nonc2N)nc2cncc(OC3CCNCC3)c21 +Cc1cc2c(-c3ccc(NS(=O)(=O)CCN)cc3)ccnc2[nH]1 +COc1cc(NC(=O)NCc2ccc(C=CC(=O)NO)cc2)ccc1-c1cnco1 +COc1ccc2ncc(-c3cccc(C(F)(F)F)c3)n2n1 +Cc1nc(C(C)(C)NC(=O)c2ccc(C3CCOCC3)c(OCC3CC3)n2)no1 +O=C(Nc1cccc(Cl)c1)NC1C(=O)N(c2ccccc2)c2ccccc2N(C2CC3CCC2C3)C1=O +COC(=O)c1[nH]c(C(C)(C)C)cc1NC(=O)Nc1ccc(Cl)cc1 +CN(C1(C(=O)O)CCCC1)S(=O)(=O)c1ccc2c(Cl)cnc(N=C(N)N)c2c1 +O=C(C=CC#Cc1ccccc1F)NC1=C(C(=O)O)CCCC1 +N#Cc1cccc(S(=O)(=O)c2sc3ncccc3c2-c2ccc(Cl)cc2)c1 +CC(C)n1c(=O)n(C(=O)NCCN2CCNCC2)c2ccccc21 +O=C(NCc1ccc(OCC(F)(F)F)cc1)C1c2ccccc2C(=O)N1CCc1ccccn1 +Cc1ccc(C=CC(=O)Nc2ccc3nc(N4CCN(C)CC4)cc(C)c3c2)cc1 +Nc1ccc(CC(=O)Nc2n[nH]c3ccc(N4CCCS4(=O)=O)cc23)cc1 +COc1cc(N2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(C1CCCC1)c1ccccc1C(=O)N2C +COc1cc(-c2nc3ccc(Cl)cn3c2NC2CCCCC2)ccc1OCCCNC(=O)Nc1ccc(OC(F)(F)F)cc1 +O=C(CC[n+]1cccc(F)c1)Nc1ccc2nc3c4[nH]c5ccccc5c4ccn3c(=O)c2c1 +COc1ccccc1N1CCN(CCCCCc2cn(-c3ccc(-c4ccsc4)cc3)nn2)CC1 +Cc1ccccc1CN1C(=O)CCc2cc3cc(c21)OCC=CCOC1CC(CO)N(C1)c1cc(n2ncc(Cl)c2n1)N3 +CN1C(=O)C2(N=C1N)c1cc(-c3cccnc3F)ccc1OC1CCCOC12 +O=C(O)C1=C(C(=O)Nc2c(F)cc(-c3cccc(OC(F)(F)F)c3)cc2F)COC1 +COc1ccc(-c2cnnn2-c2cc(OC)c(OC)c(OC)c2)c(O)c1 +NCCCNCCCCNCCCNC(=O)C(Cc1ccc(O)cc1)NC(=O)CC1CCCCC1 +Fc1cnc(OC2CN(c3ccc4ccccc4n3)C2)c(N2CCC(F)(F)CC2)c1 +O=C(Nc1n[nH]c2cc(-c3ccc(O)cc3)ccc12)c1ccc(OCCN2CCCCC2)cc1 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(OCC4CCCO4)cc3)ncc2F)c1 +O=C(CSc1nc2ccccc2c(=O)n1C1CC1)c1cccs1 +O=C(O)CCc1ccccc1CC1=C(c2nc(C(=O)NCCc3ccc(Cl)cc3)co2)CCCC1 +O=C(O)C(=Cc1c(C(=O)O)[nH]c2cc(Cl)cc(Cl)c12)c1ccco1 +CCOC(=O)N1CCC(N(C(=O)c2ccc(-c3cnco3)cc2)C2CC2)CC1 +Cc1nc2nc(C)c(CN)c(-c3ccc(Cl)cc3Cl)n2n1 +CN1CCN(c2ccc([N+](=O)[O-])c(N3CCCCC3)c2)CC1 +CC(C)CN(NC(=O)OC(C)(C)C)c1nc(C#N)ncc1Cl +Cc1cncc(C2=CCC3C4CC=C5CC(NC(=O)C6CC6)CCC5(C)C4CCC23C)c1 +CNC(=O)c1cc2c(Oc3ccc(-n4cncn4)cc3)cncc2s1 +CC(CCc1ccc(OCc2c(F)cc(F)cc2F)cc1)(C(=O)NO)S(C)(=O)=O +C=S(C)(=O)NC(=O)c1c[nH]c(-c2cc(Oc3ccc(NC(=O)Nc4cccc(C)c4)cc3)ccn2)c1 +Fc1ccc(-c2[nH]cc(C3=CC4CCCCN4CC3)c2-c2ccncc2)cc1 +CN1C(=O)NC(=O)C1=Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1 +COc1cc2nc(N(C)C(C)C)nc(NC3CCN(C)CC3)c2cc1OC +O=C(Nc1cccc(OCC(O)CN2CCc3ccccc3C2)c1)c1cnccn1 +COc1ccc(C(=O)N2CC(Oc3nccc(C#N)c3C)CCC2C)c(C2CC2)n1 +CNC(=O)CCn1ncc2cc(Nc3ncc(F)c(Nc4ccc5c(c4)OCCO5)n3)ccc21 +COC(=O)N1Cc2[nH]c(-c3cc(C(=O)N4CCC(c5ccc(C#N)cc5)CC4)c(C)cc3C)nc2CC1C +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc(C(=O)c3ccccc3F)c2)[nH]c1=O +O=S(=O)(c1ccccc1)C1(c2cc(F)ccc2F)CCCCC1 +COc1ccccc1-c1c(C(N)=O)sc2cnc(Nc3cc4c(cc3OC(C)C)N(C)C(=O)CCC4)nc12 +Cc1cc(-n2ccc(N3CCNC3=O)n2)c2c(n1)N(c1ccc(C#N)cc1OC(F)(F)F)CC2 +COc1ccc(C#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cc(Cl)ccc1C)C2=O +CCN1CCN(c2ccc(Nc3nccc(-c4sc(NC5CCCC5)nc4C)n3)nc2)CC1 +CCC(C)C1=NC2CCC34CC35C(=O)CC3(C)C(C(C)N(C)C)C(O)CC3(C)C5CCC4C2(C)CN1 +COc1ccc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c2ccc(C(F)(F)F)nc12 +CC(C)c1ccc2nc3ccc(C(O)=NCCCCc4ccncc4)cn3c(=O)c2c1 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(-c2c(CC(=O)O)cnc3ccccc23)cc1 +COc1cc(OC)cc(N(CC(C)NC(C)C)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +CC(C)CNc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +CCOC(C)OC1CC(C(=O)OC)C2(C)CCC3C(=O)OC(c4ccoc4)CC3(C)C2C1=O +CC(CO)NC(=O)CCCC=CCC=CCC=CCC=CCCCCc1ccccc1Br +O=C(CCC(=O)Nc1nc(-c2ccccc2)cs1)NCCCCNc1c2c(nc3ccccc13)CCCC2 +COc1cc(F)cc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(OC(F)(F)F)c2)c1 +O=S(=O)(c1ccc2[nH]ccc2c1)c1cc(Cl)c2oc3c(c2c1)CNCC3 +CCCCOc1ccc2c(C#N)cn(-c3ccc(C(=O)O)c(O)c3)c2c1 +Cc1cccc(NC(=O)Nc2cccc(C#Cc3cncc(C(=O)N=S(C)(C)=O)c3)c2)c1 +O=C(c1ccc(OCCCCc2c[nH]cn2)cc1)C1CC1 +CC(=O)N(O)C(c1ccc(OCCc2ccccc2)cc1)C(C)C +CNC(=O)CN1N=C(c2ccccc2)C2(CCN(C3CCC(C(C)C)CC3)CC2)C1=O +CN(CCc1ccccc1)C1CCC(c2c[nH]c3ccc(C#N)cc23)C1 +Cc1ccc2c(c1)C(=O)N(C(C)COC(=S)Nc1ccc(Cl)cc1)C2=O +CN=C(N)c1ccc(C(=O)N2CCN(S(=O)(=O)c3ccc4cc(Br)ccc4c3)CC2)cc1 +CCCc1nn(C)c2c(=O)nc(-c3cc(S(=O)(=O)N4CCN(CC)CC4)ccc3OCC)[nH]c12 +CC(C)(C)Cc1cnc(CCc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 +COc1cc(OC)c(N(C)C(=O)c2cc3c(s2)-c2ccccc2S(=O)(=O)C3)cc1Cl +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4cc(C)ccc4[nH]3)CC3CC123 +c1ccc2c(N3CCN(CCc4ccc5[nH]nnc5c4)CC3)cccc2c1 +CC(C)N1CCC(Oc2ccc3c(c2)cc2n3CCN(Cc3ccccc3F)C2=O)CC1 +CC1CN(c2nc(N3CCOCC3C)c3ccc(-c4ccc([N+](=O)[O-])cc4)nc3n2)CC(C)O1 +COc1cccc2cc(C(=O)NCCCCN3CCN(c4cccc(Cl)c4Cl)CC3)oc12 +CCC1OC(O)=C2C1=NC1=C(C(=O)OC1)C2c1ccc(F)c(Br)c1 +N#Cc1cc2c(cn1)[nH]c1ncc(-c3ccccc3O)cc12 +Cc1cc(COc2ccc(S(=O)(=O)CC3(CC(=O)NO)CCCNC3)cc2)c2ccccc2n1 +Cc1nn(-c2ccc(C#N)c(C(F)(F)F)c2)c(C)c1Cc1ccc(F)cc1 +CCC1CCCC(C2(OC(=O)N3CCN(C(C)(C)CO)CC3)CC2)N1S(=O)(=O)c1cc(F)cc(F)c1 +O=C(CCl)Nc1cc(=O)oc2cc(OCc3cccc(Cl)c3)ccc12 +COc1cc2ncnc(Nc3cccc(Cl)c3F)c2cc1CN1CCOCC1 +CC(C)(C)c1ccc(N2CCN(Cc3ccc4ccc(=O)oc4c3)CC2)cc1 +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)NCCCC(N)C(=O)O +CC1(C)OCc2c(Nc3n[nH]c4c(Cl)cccc34)nc(-c3cn[nH]c3)nc21 +COCCN1CCN(c2ncc3ncnc(Nc4cc(C(=O)Nc5ccc(C#N)c(C(F)(F)F)c5)ccc4C)c3n2)CC1 +CC1(C)CCN(C2C3CC4CC2CC(O)(C4)C3)C(=O)c2cnn(C3CCCCC3)c21 +Cc1cccc(C)c1-c1ccccc1CN(C(=O)c1ccc(-c2ccc(C#N)cc2)o1)c1ccc(N2CCNCC2)cc1 +CCC(=O)n1nc(-c2ccco2)nc1SCc1ccccc1 +O=C(NCC1CCN(CCCCCC(c2ccc(F)cc2)c2ccc(F)cc2)C1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1cc(Cl)nc(C)c1C(=O)NCCC(C)N1CCC(N(Cc2ccsc2)C(=O)NO)CC1 +CCN(CC)CCCC(C)Nc1c2ccccc2nc2ccccc12 +CCOc1cc(C2(C#N)CC3CC(C(=O)O)CC3C2)ccc1OC +CN(C)c1ccc2c3c1OC1C(O)C=CC4C(C2)N(C)CCC341 +COc1cc(N2CCOCC2)ccc1Nc1ncc2cccc(-c3ccccc3)c2n1 +O=C(O)CC1CCCc2c1n(Cc1cccc(OCCCC#Cc3cccnc3)c1)c1ccc(F)cc21 +CSc1ccccc1N1CCN(CCCCn2ncc(=O)n(C)c2=O)CC1 +Cc1ccc2[nH]c3c4c5ccccc5nc-4c[nH]c3c2c1 +Cc1ccc(F)c(NC(=O)Nc2ccc(Oc3ccnc4cc(C(=O)NCCCN5CCN(C)CC5)sc34)cc2F)c1 +CCN(CC)C(=O)N1CCC(CCN2C3CCC2CC(n2c(C)nc4ccccc42)C3)(c2ccccc2)CC1 +CC1(C)Cc2n[nH]c(=O)c3cccc4c3c2c(n4CCN2CCCC2)C1 +CN1CCN(c2nc(NCCS(=O)(=O)Nc3ccccc3)c3ccc(Cl)c(Cl)c3n2)CC1 +CC12C=CC(=O)C=C1CCC1C2CCC2(C)C(=O)OCC12 +Cn1cnc(-c2cccc(NC(=O)Nc3cc(C(F)(F)F)ccc3F)c2)c1-c1cc2c(N)ncnc2s1 +Cc1ccc2c(c1)C(=O)N(CCCCN1CCC(n3c(=O)oc4ccccc43)CC1)S2(=O)=O +CC(Nc1c(F)ccc(OCC(=O)O)c1F)c1cc(-c2cccc(F)c2)ccc1F +CCC(CO)Nc1nc(N2CCOCC2)[nH]c(=O)c1-c1nc2ccccc2s1 +NC(=S)N1N=C(c2cccc(Br)c2)CC1c1cccc(Cl)c1Cl +CC(C)NC(=O)Nc1cccc(CN2C(=O)C(NC(=O)Nc3ccc4ccsc4c3)CCc3ccccc32)c1 +Cc1cn(-c2ccc3n(c2=O)CCN(C2CCC2Oc2ccc(Cl)c(C(C)C)c2)C3=O)cn1 +O=C(Nc1ccc(F)cc1C(F)(F)F)c1cc[nH]n1 +COc1cc(C)c2nc3[nH]nc(C)c3c(N3CCC(O)CC3)c2c1 +CN(C)CCN1C(=O)c2cccc3cc4nc(Cl)sc4c(c23)C1=O +C#CCNCC(=C)c1cccc(OCc2cccc(F)c2)c1 +CNc1nc(Cl)c(Cl)c(N2CCN(CCC3CCC(NC(=O)N4CCOCC4)CC3)CC2)n1 +CN(Nc1nc2c(c(=O)n1N(C)C)CN(C(=O)COc1ccc(Cl)cc1)CC2)c1ccc(Cl)cc1 +CC(=O)N1CCN(c2ccc(CN(C3CCC3)S(=O)(=O)c3cc(C)cc(C)c3)c(F)c2)CC1 +CN(CCN1CCCCC1)C(=O)C1CCC2(CC1)OC(=O)c1ccccc12 +O=C(Oc1cc2oc(=O)c3c(c2cc1Cl)CCCC3)c1cccs1 +COc1ccc(Nc2nc(-c3ccc(C(N)=O)cc3C)cn3ccnc23)cc1OC +Nc1ncc(-c2ccc(-c3ccccc3C(=O)N3CCOCC3)cc2F)cn1 +CCCN1CC(c2ccccc2)N(C2CCN(C(C)CCNC(=O)c3c(C)cc(Cl)nc3C)CC2)C1=O +Cn1ncc(NC(=O)c2nc(C3=CCCC3)sc2N)c1C1CCC(N)C(F)CO1 +CCCCCCCCOc1ccc(C=CC(=O)Nc2cccc3c2OC(c2nnn[nH]2)CO3)cc1 +COCCN(CCOC)c1nc(C)nc(Nc2c(C)cc(C)cc2C)c1SC +N#CCCNC1CCC(=CCn2cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n2)CC1 +CC(C)(CC(O)(Cc1cc2ccccc2[nH]1)C(F)(F)F)c1cc(F)cc2c1OCC2 +CC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cc(Cl)cnc32)CC1 +CN(C)c1ccc(C(=O)O)c(Oc2nc(Oc3cccc(-c4cccc(CN)c4)c3)c(F)c(N3CCNCC3)c2F)c1 +Cn1ccc(CNC(=O)c2ccc(NC(=O)N3Cc4cccnc4C3)cc2)n1 +Cc1ccnc(Oc2ccc(-c3cc4c(cc3F)ncc3nc(C)n(C5CCN(C(N)=O)CC5)c34)c(F)c2)n1 +CCC(CC)CN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +CN1CCN(c2cc(C(F)(F)F)nc(N3CCCC(C(=O)NCCc4ccc(C#N)cc4)C3)n2)CC1 +COC(C(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)C(C)C)c1ccccc1 +COc1ccccc1Nc1nc(-c2ccc(-c3ccccc3)cc2)c(CC(=O)O)s1 +O=C(Nc1cc(C(F)(F)F)no1)NC12CC3CC(CC(C3)C1)C2 +COc1cc(OCCO)cc(N(CC2CC2)c2ccc3ncc(-c4cn[nH]c4)nc3c2)c1 +O=C(c1ccc(Cl)cc1-n1nccn1)N1CCOCC1Cc1cccc(-c2ncon2)c1 +Cc1cc(C)[n+](NC(=O)c2[nH]c3ccc(S(N)(=O)=O)cc3c2-c2ccccc2F)c(C)c1 +O=C(OCCCCN1CCC(OCc2ccccc2)CC1)c1ccc(F)cc1 +COc1ccc(C)n2nc(CCc3nc(-c4cccs4)cn3CCCC#N)nc12 +Cc1c(CC(=O)O)c2ccc(F)cn2c1Sc1ccc(S(C)(=O)=O)cc1F +Cc1cc(-c2nc(-c3ccc(OC(F)(F)F)c(CO)c3)n3c2CCOC(C)C3)cc(C)n1 +CC1CCCC(C)N1Cc1cc2c(N)nc(-c3ccc(C(F)F)o3)nc2s1 +O=C1Nc2cccc3c2C1(CCCCN1CCc2n[nH]cc2C1)CCC3 +NC(=O)c1cc(NC(=O)c2cc(-c3ccccn3)c(F)cc2Cl)n(-c2ccccc2)n1 +CN(C)C(=O)c1ccc(N(CC2CCCC2)C(=O)c2ccc(O)cc2O)cc1 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(-c3ccccc3)cn2)cc1 +O=S(=O)(NCc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1cccc(F)c1 +NCCCn1nc(C2=C(c3cn(-c4csc5ccccc45)c4ccccc34)C(=O)NC2=O)c2ccccc21 +Clc1cc(Cl)cc(C2OC3(CCN(Cc4ccc(N5CCCC5)cn4)CC3)c3ccccc32)c1 +CCc1cc(C)c(-c2nnc(COC)[nH]2)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +O=C(NC1CC(c2ccccc2)CCN(CC2CC2)C1=O)N1CCC(n2nc(-c3ccccc3)[nH]c2=O)CC1 +CC(CO)n1c(=O)n(C)c2cnc3ccc(-c4cnn(C)c4)nc3c21 +CON=C(c1ccc(CN2CCC3(CC2)OCc2cc(F)ncc23)cc1)c1ccc(F)c(F)c1 +O=C(C1CCCN(c2ccc3nc(C4(n5cc(F)cn5)CC4)[nH]c3n2)C1)N1CCCC1 +NS(=O)(=O)c1ccc(C2=C(c3ccc(C(F)(F)F)cc3)CCC2)cc1 +COc1ccccc1N1CCN(CCCCNC(=O)c2ccc(C(C)(C)C)cc2)CC1 +O=C(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1c[nH]c2c(-c3nnco3)ccc(F)c12 +CC(=O)Nc1c(Cl)cc(CNC(N)=NC(=O)C2CC(O)CN2c2ccccc2)cc1Cl +CC1=C(C(=O)OC2CCCC2)C(c2[nH]cnc2Cl)C(C(=O)OC2CCCC2)=C(C)N1 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CC(C)CC(C)C1 +Cc1ccc2nc(N(Cc3cccnc3)C(=O)CCc3ccccc3)sc2c1 +NS(=O)(=O)c1ccc(CN2C(=O)c3cc(Cl)c(Cl)cc3C2=O)cc1 +Cc1ncc(Nc2cncnc2)c(C(=O)Nc2cn(C)nc2C(=O)NCC(C)(C)O)n1 +CN1Cc2c(C3=CCN(C(=O)OC(C)(C)C)CC3)[nH]c3ncc(F)c(c23)-c2cc(F)ccc21 +CCN(CC)S(=O)(=O)NC(=NC(C)C)N1CC(c2ccccc2)C(c2ccc(Cl)cc2)=N1 +CCc1ccc(S(=O)(=O)Oc2ccc(Cn3ccnc3)cc2)cc1 +CC(C(=O)NC1C2CC3CC1CC(O)(C3)C2)N1CCc2ccc3c(c2CC1)OCO3 +CCCC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12 +CS(=O)(=O)c1ccc(-c2ccc3ncc(-c4ccc(C(F)(F)F)cc4)n3n2)cc1 +O=c1cc(N2CCOCC2)oc2c(-c3cccc(-c4ccsc4)c3)cccc12 +O=C(NC(CCCCCCSSc1ccccn1)C(=O)OCc1ccc([N+](=O)[O-])cc1)OCc1ccccc1 +CC1C2Cc3ccc(C(N)=O)c(N)c3C1(C)CCN2CC1CC1 +N#Cc1c(N)nc2sc(C(=O)c3cccc(Cl)c3)c(N)c2c1-c1ccccc1I +COc1ccc(C2CC2c2ccc(OC)c(OC)c2OC)cc1N +CCOC1(OCC)C2c3c(Br)cccc3C([n+]3ccccc32)C1(C)C +CN(C)C1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cn5ccc(C#N)cc5n4)c3)sc2C1 +CCCCCCCN1CCOC(COc2cc3ncnc(Nc4ccc(Cl)c(Cl)c4)c3cc2OC)C1 +O=c1cc(N2CCOCC2)nc(Cc2nc3c(F)cccc3o2)[nH]1 +CC(C)c1c(C(=O)NCc2ccc(F)c(F)c2)c2ccc(N3CCOCC3)cc2n1Cc1ccccn1 +COc1ccc(C=CC(=O)N2CCN(C(=O)c3ccc(C)cc3)CC2)cc1 +COCCNC(=O)CCc1c(C)c2c(OC)cc(O)c(C=O)c2oc1=O +O=C(Nc1ccc(F)cc1)c1ccc(SCc2ccccc2)nc1 +Cc1ccccc1-n1c(Cn2nc(CF)c3c(N)ncnc32)cc2cccc(C)c2c1=O +CCCCCCCc1ccc(NC(P(=O)(O)O)P(=O)(O)O)cc1 +CCc1cc(C(=O)NC2CC(C(=O)NCc3ccc(C(F)(F)F)cc3)N(C(=O)c3coc4ccccc34)C2)n(C)n1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccnc(F)c3)n2)CCN(Cc2cn3ccccc3n2)CC1 +COCCCOc1cc(CC(CC(N)C(O)CC(C(=O)NCC(C)(C)CNC(C)=O)C(C)C)C(C)C)ccc1OC +O=C(NC1CCCCC1C(=O)NC(CCc1ccccc1)C(=O)CO)OCc1ccccc1 +COc1ccc2c(c1)N(CCCCCC(=O)NO)C(=O)c1ccccc1S2 +O=C(O)CC(c1ccc(Cl)c(Cl)c1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)CC1CC1 +CC1CCC2C(C)C(OO)(C(F)(F)F)OC3OC4(C)CCC1C32OO4 +CCCN(CCc1ccc(Nc2ccc([N+](=O)[O-])c3nonc23)cc1)C1CCc2c(O)cccc2C1 +O=C(O)c1ccc2c(c1)nc(NCc1cccnc1)c1nc(NC3CC3)ncc12 +CC1COCCN1c1nc(N2CCN(C)CC2)nc2[nH]c(-c3cccc4[nH]ccc34)nc12 +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4cccnc4)cc3)nc2c1 +Clc1cccc(C(c2ccc(CN3CCCC3)cc2)(c2ccccn2)n2ccnc2)c1 +O=C1CC(c2c[nH]c3ccccc23)C(=O)N1CCCCN1CC=C(c2c[nH]c3ccc(Cl)cc23)CC1 +COc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)c1F +Cc1cncc(-n2c(C(C)Nc3nc(N)nc(N)c3C#N)nc3cccc(Cl)c3c2=O)c1C +CC(OC1CC(C)N(C)C(=O)CC1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(C(O)c1ccccc1)N(C)S(=O)(=O)c1ccccc1-c1ccc(-c2cnc(N)c(F)c2)c(F)c1 +C=CC(=O)Nc1ccc(CCn2c(=O)c(-c3cc(OC)cc(OC)c3Cl)cc3cnc(NCCN(CC)CC)nc32)cc1 +O=c1[nH]cnc2[nH]c(-c3ccnc(C=Cc4ccc(CN5CCOCC5)cc4)c3)cc12 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1ccc(Cl)cc1 +COc1ccccc1C1CCN(c2ccn3c(CC4CC4)nnc3c2Cl)CC1 +NCCNC(=O)c1cc(N(CCCl)CCCl)c([N+](=O)[O-])cc1[N+](=O)[O-] +CCc1cc(C)c(-c2nc3c([nH]2)COCC3C)cc1C(=O)N1CCC(c2ccc(C#N)cc2)CC1 +Cn1cnc2cc(-c3ccc(N)c(S(C)(=O)=O)c3)nc(NCCCO)c2c1=O +O=C1c2ccc(F)cc2C(=O)N1CCCCCN1CC=C(c2c[nH]c3ccccc23)CC1 +CCOC(=O)C(C)NP(=O)(OCC1OC(n2cnc3c(N)nc(NN)nc32)C(C)(O)C1O)Oc1ccccc1 +CC(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2)o1)C(=O)N(CC(=O)O)CC(=O)O +O=C(NCC#Cc1ccc2ncnc(NC3CCOCC3)c2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +O=C(O)c1ccccc1Nc1ccnc(OCC2CCCCC2)n1 +Cc1cc(C(=O)Nc2ccc(-c3ccccc3CN(C)C)cc2F)n(-c2ccc3cc(Cl)ccc3c2)n1 +COc1cc(-c2nn(C3CCC(N4CCN(C)CC4)CC3)c3ncnc(N)c23)ccc1NCc1ccco1 +CC1(C#N)CCCC1Nc1c(C(N)=O)cnn2cc(-c3ccccc3)cc12 +NC(=O)c1cccc2[nH]c(C3CCC(=O)N3)nc12 +O=C(NCC1CCCC1)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +C=CCN1C(=O)C(=Cc2ccc(O)c(Br)c2)SC1=S +O=C(O)C12CCN(c3nccc(-c4ccccc4OCc4ccc5c(c4)CCN(C4CCOCC4)C5)n3)CC1C2 +CCc1nc2c(C)cc(C)nc2n1Cc1ccc(C(=Cc2nn[nH]n2)c2ccccc2)cc1 +O=C1NC(=O)c2c1c1c3cc(Cl)ccc3[nH]c1c1cccn21 +CCN(CCCN1CCC2(CC1)OCc1ccccc12)C(=O)C(c1ccc(F)c(F)c1)N1CCCC1=O +COc1ccc(Nc2nnc(Cn3c(C)nc4ccccc43)s2)cc1 +COc1cc(CN2CC(C(=O)O)C2)ccc1OCc1ccccc1Cl +COc1cc2cc(NC(=O)c3ccc(O)c(CC=C(C)C)c3)c(=O)oc2c(C)c1OC1CCN(C)CC1 +Cc1ccc(COc2cc(F)c3nc(CC4(C(=O)O)CCCC4)n(Cc4ccc(C(F)(F)F)cc4)c3c2)nc1 +CN(C)c1ccc(NC(=O)NCCCCCCC(=O)NO)cc1 +CCN1C(=S)N2CCCC2c2c(N3CCOCC3)nc(-c3ccc(OC)cc3)nc21 +O=C(NC(Cc1ccc2nc(-c3ccncc3)ccc2c1)C(=O)O)c1c(Cl)cccc1Cl +NS(=O)(=O)c1ccc(Nc2nccc(-c3ccc(S(=O)(=O)N4CCNCC4)cc3)n2)cc1 +CN1CCCC(n2cc(S(=O)(=O)C3=C(Cl)NC4SC=CN34)c3cccnc32)C1 +COc1cc2c(NC3CCN(C(C)C)CC3)nc(C3CCCCC3)nc2cc1OCCCN1CCCCC1 +NCCCOc1cc2c(c(-c3ccc(Nc4nc5ccccc5o4)cc3)c1)CNC2=O +Nc1cnc(-c2ccc(C3CCC3)c(OCc3ccc(F)cc3)c2F)cn1 +CNc1cc(NC(=O)OC)ccc1Nc1c2ccccc2nc2c(Cl)cccc12 +O=C(Nc1ccc(OC(F)(F)Cl)cc1)c1ccc(N2CC(O)C(O)C2)c(-c2ccn[nH]2)c1 +CCNC(=O)C(=O)C(CC)NC(=O)C(CC(C)C)NC(=O)c1ccc2ccccc2n1 +O=C(Nc1cnc(-c2c(F)cncc2F)c(-c2cccnc2)n1)C1CC1 +CC(C)(N)C(=O)NC(CCCc1ccccc1)C(=O)N1CCN(c2ccccc2NS(=O)(=O)CC(=O)O)CC1 +COC(=O)C1=C(c2ccc(F)c(Cl)c2)CC2CCC1S2 +COc1nc(N(C)C)ncc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cn1)N(c1cc(Cl)ccc1C)C2=O +COc1ccc2c(c1)c(CCN(C)C)cn2S(=O)(=O)c1ccc(NC(C)=O)cc1 +CNc1cc(C2(C(=O)Nc3cc(C(=O)Nc4ccc(CN5CCOCC5)c(C(F)(F)F)c4)ccc3C)CC2)ncn1 +CC(C)c1ccc(Cl)cc1-c1[nH]c(-c2ccnc(N)n2)cc1C(N)=O +CC(=O)NC(Cc1ccccc1)C(=O)CCC(=O)N1CCCC1C(=O)O +CCCNCCN1CN(c2ccccc2)C2(CCN(Cc3c(Cl)cccc3Cl)CC2)C1=O +CCNC(=O)C1OC(n2cnc3c(N)nc(C#CCN)nc32)C(O)C1O +CCN(CC)C(=O)NC1CCN(C(c2ccc(OC(C)C)cc2)c2cccnc2)CC1 +CCn1ncnc1C1=C(C)Nc2ccnn2C1c1ccc(Cl)c(Cl)c1 +NCCCCOCc1ccn2ncnc(Nc3ccc4c(cnn4Cc4cccc(F)c4)c3)c12 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccccc3)n(CC(=O)N3CCS(=O)(=O)CC3)c2c1 +O=C(NCCCNc1nc2cccc(Br)c2c2[nH]c3ccccc3c12)Nc1ccccc1 +CCCCCCCCCOc1ccc(NC(=O)ON=C(C)C)cc1 +COc1ccc(C(=O)N=C(Nc2cccc(C)c2)NC2CCCCN(CC(=O)N3CCCC3)C2=O)cc1 +COC(=O)C1CCN(Cc2ccc(OCCCN3CCN(c4ccc([N+](=O)[O-])cc4)CC3)cc2)CC1 +CC1CCc2nc(CCCCN3CCN(c4ccc5ccccc5n4)CC3)n(N)c(=O)c2C1 +CCn1ccc2ccc3c(c4c(c5c6ccccc6n(CCCO)c35)C(=O)NC4=O)c21 +CS(=O)(=O)c1ccc(-c2ccc(F)c(F)c2)c(C(=O)N2Cc3cc(C(F)(F)F)cnc3C2)c1 +CC(=O)OC1OC(C)C2C(C=CC3CCCC(C)N3C)C3CCCCC3CC12 +CC1(C)OB(c2ccc(NC(S)=Nc3ccc(S(N)(=O)=O)cc3F)cc2)OC1(C)C +CC(C)N1CCN(c2ccc(Nc3ncc4cc(C(=O)N(C)C)n(C5CCCC5)c4n3)nc2)CC1 +COc1ccc(S(=O)(=O)N(Cc2ccc(F)c(F)c2)C(Cc2cccs2)C(=O)NO)cc1 +O=C(C=Cc1ccc(Cl)c(Cl)c1)N1CCC(C(CO)N2CCC(c3c[nH]c4ncccc34)CC2)CC1 +CC(C)Oc1cc(C(=O)O)cc(NC(=O)c2nc3c(s2)CN(C(C)C)CC3)c1CCC(=O)Nc1ccc(Cl)cc1 +Cc1cc(Cl)cc2c(C(O)c3ccccn3)c3c(C)n[nH]c3nc12 +NCC1OC(OC2C(N)CC(N)C(OC3OC(CSCCOCCS)C(O)C(N)C3O)C2O)C(N)CC1O +CC(C)CCn1cc(NC(=O)c2ccc(NC(=O)N3Cc4ccccc4C3)cc2)cn1 +C[S+]([O-])CCOc1ccc2ncc(-c3cc4ccccc4o3)n2n1 +N=C(N)c1ccc(-c2ccc(-c3cn4c(n3)CCC(C(=N)N)C4)o2)cc1 +O=C(NC(CO)c1ccc(Cl)cc1Cl)C1CCc2ncsc21 +Cc1nc(N2CC3CN(C(=O)c4ccccc4-c4ncn(C)n4)CC3C2)nc(C)c1Cl +Cc1nc(C(=O)N2CCC2c2nc(-c3ccccc3OC(F)(F)F)no2)c(-c2ccccc2F)s1 +Cc1cccc(C)c1Oc1c(C(=O)N2CCNCC2)c2ncccc2n1-c1ccccc1 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4ccccn34)c12 +CSc1nccc(-c2c(-c3ccc(F)cc3)nc3nc(N)ccn23)n1 +CCCCCCCCCc1ccc(CN2CCC(P(=O)(O)O)C2)cc1 +Nc1nc2c(NCc3ccccc3)cccc2c2cn(-c3ccccc3)nc12 +O=C(NCCC1OCCO1)c1cccnc1Oc1ccc(Nc2ccccn2)cc1 +NC1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)CC1 +O=C(Cc1nc(N2CCOCC2)cc(=O)[nH]1)N1c2ccccc2CC1c1ccccc1 +COc1cnc(C(=O)Nc2ccc3c(c2)C2(CCOC(N)=N2)c2cc(C4CC4)ncc2O3)cn1 +Cc1nnc2sc(C(=O)NC3CN(c4ccccc4F)C3)c(N)c2c1C +COc1nc(NCCc2ccc3c(c2)OC(F)(F)O3)cc(-c2cccnc2)n1 +CC(C)(C)NC(=O)NCCN1CCN(CC(=O)Nc2cc(Cl)cc(Cl)c2)CC1 +O=C1Nc2cc(F)ccc2C1CCCCN1CCN(c2cccc(Cl)c2)CC1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3CCC(NCC(O)CO)CC3)cc12 +Cc1cccc(C(=O)c2cccc(C(=NNC(N)=S)c3cccc(C)c3)c2)c1 +CCOc1ccc(CC(NC(=O)c2ccncc2)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)c(F)c2)cc1 +Cc1ccc(Cc2cc[n+](C)c(COc3ccc(C)cc3)c2)cc1 +CC(C)CN1CCC(S(=O)(=O)CCCOc2ccc3[nH]c4nc(O)nc-4cc3c2)CC1 +O=C(NC1CCCC(O)C1)c1noc(-c2ccc(C(F)(F)F)cc2)c1CO +C=CC(=O)Nc1cnccc1Nc1nc(NC2CCOCC2)ncc1Cl +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2ccc(OC(F)(F)F)cc2)cc1 +Cc1ccc(CN2C(=O)N(c3cnn(Cc4c(C)noc4C)c3)C(=O)C2(C)C)cc1 +Cc1cnc(Nc2ccc(C(=O)Nc3c(C)cccc3C)cc2)nc1-c1ccncc1 +CN(C)C(=O)C1CC1c1ccc(-c2nc(C3CC3)n(C)c2Sc2ccc(Cl)cn2)cc1 +O=C(Nc1ccncc1)C(=O)c1cn(-c2ccccc2)c2ccccc12 +COc1ccc(-c2c(-c3ccccc3)c3n(c2CC(=O)O)CC(C)(C)C3)cc1 +CN1CCN(C(CN2CCN(CCCCc3cccc4ccccc34)CC2)c2cccc(Br)c2)CC1 +COC(=O)C(Cc1cccc(C(=N)N)c1)C(C)NC(=O)c1ccc(-c2ccc[n+]([O-])c2)cc1 +CCCC1(CCC)CC(C(=O)NCc2ccc(C(=N)N)cc2)n2c1c(Cl)nc(NC1CCC1)c2=O +Cc1ccc(-c2ccc3ncc4[nH]c(=O)n(-c5cccc(C(F)(F)F)c5)c4c3c2)cn1 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+COc1ccccc1Cn1ccc(C(=O)NCc2cn(-c3ccccc3)c3cc(Cl)ccc3c2=O)cc1=O +CC(=O)c1cccc(Oc2cc(Cn3ccnc3)ccc2C#N)c1 +CCCC(NC(=O)c1cocn1)c1cnc(Nc2ccc(C)nc2)c(Cl)c1 +CC(=O)c1ccc(NC(=O)CN2CCC(N3C(=O)OCc4cc(C)ccc43)CC2)cc1 +O=C1C(Nc2ccc(Br)cc2)=C(Cl)C(=O)c2ncncc21 +COc1cc(Nc2nc(-c3ccccc3)cs2)ccc1-c1cnco1 +Cc1cc(-c2cccc(C(C)Nc3cc(-c4ccc5ncsc5c4)nc(C)n3)c2)ccn1 +CCCCCC(O)C=CC=CC=CC(O)CC=CCCCC(=O)NCCO +CN(C(=O)COc1cc(Cl)cc(Cl)c1)C1CCCCC1N1CCCCCC1 +CCc1cc(C(C)=O)c(O)cc1OCCCCCC(C)(C)c1nn[nH]n1 +CCS(=O)(=O)c1ccc(OC)c(Nc2ncc(-c3cccc(C#N)c3)o2)c1 +Cc1ccnc2oc(-c3ccccc3Cl)cc(=NNC(=N)N)c12 +CSc1ccc2[nH]c3c([N+](=O)[O-])ccc4c3c(nn4CCCN(C)C)c2c1 +COc1ccc(C2=C(C(=O)c3ccc(OCCN4CCCC4)cc3)c3ccccc3CC2)cc1 +Cc1cc(C)cc(-c2[nH]c3ccccc3c2CCNCCCCCc2ccncc2)c1 +COc1cncc(-c2cc3c(cn2)cnn3-c2cccc(N3CCNCC3)n2)n1 +CCN1CCC(=O)C(=Cc2c(C(F)(F)F)nn(-c3ccccc3)c2-c2ccc(Cl)cc2)C1 +COc1cnc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)COC3F)c2)cn1 +CCOC(=O)N1CCC(N2CCC2C(=O)N2CC(S(=O)(=O)c3cccc(Cl)c3)CC2C(=O)NC2(C#N)CC2)CC1 +COc1cc(NS(C)(=O)=O)cc(OC)c1Oc1ccc(C#N)c(Cl)c1 +CCc1nc(-c2ccc(Cl)cc2Cl)c(CC)nc1NC(COC)COC +Cn1cc(C(=O)C(=O)Nc2ccc(-n3cccc3)cc2)c2ccccc21 +CCc1nccn1CCCOc1ccc(-c2cccc(C#N)n2)cc1C(F)(F)F +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCCOC)CC2 +CCCN(c1ncccn1)C1CCN(CC2CN(C(CC3CCC3)C(=O)O)CC2c2cccc(F)c2)CC1 +COc1cc(C(=O)NC2CCN(C)CC2)c(F)cc1Nc1ncc2c(n1)N(C1CCCC1)CC(F)(F)C(=O)N2C +CCC(C)c1ccc(N2CCN(CCn3c(=O)[nH]c4c([nH]c5ccccc54)c3=O)CC2)cc1 +CCC(C)CNC(=O)c1ccc(OC2CCN(CC3CCCCC3)CC2)c(Cl)c1 +O=C(O)C(Sc1nc(Cl)cc(Nc2ccc3c(c2)CCC3)n1)c1cccc2ccccc12 +CN(C)C1CCN(C(=O)c2nn(C)cc2NC(=O)c2nc(C3CC3)ccc2Nc2cncnc2)C1 +COc1ccccc1N1CCN(CCN=C(N)C2CCCCC2)CC1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCN(c3ccc(Cl)cc3)CC2)cc1 +N#Cc1cc(S(=O)(=O)Nc2ncns2)ccc1Oc1ccc(Cl)cc1-c1ccnc(N2CCNCC2)n1 +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)cc2-c2ccc(-c3ccco3)c(C(N)=O)c2)nc1 +O=C(O)c1ccc(-c2nc(C(=O)c3c(Cl)cccc3Cl)n3c2CCCC3)c(F)c1 +Cc1cc(C#N)cc(C)c1Oc1nc(NC2CCN(Cc3ccc(S(N)(=O)=O)cc3)CC2C(=O)O)nc2ccsc12 +CC1=Nc2ccc(Cl)cc2C(c2ccccc2)N1CCN1CCN(C(=O)c2ccco2)CC1 +Cc1nc2c(C(F)(F)F)cccn2c1-c1cccc(Oc2cccc(S(C)(=O)=O)c2)c1 +O=C(O)C1CN(Cc2ccc(-c3cc4cc(Cc5ccccc5)ccc4o3)cc2F)C1 +COC1CCC2(CC1)Cc1ccc(-c3cncc(Br)c3)cc1C21N=C(C)C(N)=N1 +COc1ccc2c3c1OC1CC(O)C=CC31CCN(CCCCCCN(C)C13CC4CC(C)(CC(C)(C4)C1)C3)C2 +O=C(C1CC(Oc2ccccn2)CN1)N1CCCN(C2CCC2)CC1 +CN1CCn2c(c(C3CCCCC3)c3ccc(C(=O)O)cc32)-c2ccccc21 +CC(C)c1nnc(C(=O)C(NC(=O)Cn2c(-c3ccc(F)cc3)ncc(N)c2=O)C(C)C)o1 +CCC1C(=O)CC2CCN(CC3CCCCC3)C3CCCC1C23 +CC(C)(COc1ccc(-c2ccc(-c3ncc(C(F)(F)C(F)(F)F)[nH]3)cn2)cc1)C(=O)O +COc1cccnc1-c1cccnc1Oc1ccc(Nc2nc3ccccc3s2)cc1 +CCN(CC)C(=O)c1ccc(C(c2ccccc2)N(C)CCNC)cc1 +O=C(NC1CC1)c1ccc(-c2cnc3c(SCCCCO)nc(-c4ccccc4)cn23)cc1 +CCC(Oc1ccc([Se]Cc2sc(-c3ccc(C(F)(F)F)c(F)c3)nc2C)cc1C)C(=O)O +CON(C)C(=O)N1N=C(c2cc(F)ccc2F)SC1(CCCN)c1ccccc1 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1n[nH]cc1Nc1nc(Cl)nc2ccccc12 +O=C(OCc1ccc(F)cc1)N1CCC(CNc2ncccn2)CC1 +Cc1cc2c(cc1C(F)(F)F)N(C(=O)Nc1ccc(OCc3ncccc3C)nc1)CC2 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+CN(C)CCn1ccc(Nc2ncc3c(n2)-c2c(nn(C)c2-c2sccc2Cl)CC3)n1 +O=C(Cc1ccccc1)N1CCc2nc(O)n3cc(-c4ccccc4F)nc3c2C1 +CS(=O)(=O)c1cccc(-c2noc(-c3cnn(-c4ccccc4F)c3-c3ccncc3)n2)c1 +COc1ccc(CCNC(=O)CN(c2cccc(Cl)c2)S(=O)(=O)c2ccc(C)cc2)cc1OC +CN1C(=O)N(c2cccc(C(F)(F)F)c2)C2=C(C(=O)CC2)C1c1ccc(C#N)cc1-c1cnn(C)c1 +Nc1ccc(NC(=O)C=C2CC(C(=O)O)Nc3cc(Cl)cc(Cl)c32)cc1 +CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc(-c4ccccc4)cc3)n2)c(=O)c1=O +Cc1cc(C)cc(COC(=O)C(Cc2c[nH]c3ccccc23)[N+](C)(C)C)c1 +Cc1cc(Oc2ccc3c(c2)OCO3)nc(Oc2ccc(-n3ccnc3)cc2C(F)(F)F)n1 +Cc1cc(CC(CCCCNC(Cc2ccccc2)c2ccc(F)cc2)C(=O)NO)cc(C)c1F +Cc1cc(-c2cccc(Cl)c2)ncc1C1CCCN1C(=O)c1ccncc1 +CCS(=O)(=O)n1cc(C(=O)C2CSC(c3cccnc3)N2)c2ccccc21 +CN(C)c1ccc(-c2cnc3[nH]cc(-c4cn[nH]c4)c3c2)cc1 +O=c1[nH]c2c(O)ccc(C(O)CNCCOc3cccc(CNCCc4ccccc4F)c3)c2s1 +C=CC(C)(C)C12CC3C(=O)N4C(CC5(C(C)(C)C=C)c6ccccc6NC45)C(=O)N3C1Nc1ccccc12 +Cc1cnc(N2CCC(Oc3cc(F)ccc3Cl)CC2)nn1 +C[n+]1cc2c3c(ccc2c2ccc4cc5c(cc4c21)OCO5)OCO3 +CN(C)C(=O)C(C)(C)N=CC(C=N)c1ccn2c(-c3cccc(NC(=O)NCC(F)(F)F)c3)cnc2c1 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+CCCCCC1Oc2cccc(OC)c2-c2ccc(NS(C)(=O)=O)cc21 +CC(C)CCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cn1 +Brc1ccc2c(NC3=NCC4(CN5CCC4CC5)O3)nccn12 +O=C(Nc1ccc2nc(N3CCNCC3)[nH]c(=O)c2c1)c1ccc(C2CCNCC2)cc1 +COc1ccc(C=C2CC(CO)(COC(=O)c3c(C(C)C)cc(C(C)C)cc3C(C)C)OC2=O)cc1 +Cc1ccc(C#Cc2cccc(C#Cc3ccc(C)cc3)[n+]2C)cc1 +CSc1ncc(C(=O)N2CCNc3ccccc32)c(Oc2cc(Cl)ccc2Cl)n1 +CCCCNC(=O)C(C)CC(O)C1CSCCCCCCSCC(NC(C)=O)C(=O)NC(C)C(=O)N1 +CN1CCN(c2cc(N3CCOCC3)cn3c(=O)c(O)c(-c4ncc(Cc5ccc(F)cc5)s4)nc23)C1=O +CC1CCC2C(C)C(OC(=O)CCC(=O)O)OC3C4(C)CCCC1C23OO4 +Cc1cc(Cl)c(OCCOc2ccc(C3CCNCC3C(=O)N(Cc3cc(CNC4CC4)ccc3Cl)C3CC3)cc2)c(Cl)c1 +CCOC(=O)C1CC1Cc1c(Br)cc(OC)c(OC)c1Br +CCn1ccc(CNc2cc(OCC3CC3c3ccc(OC)cn3)nn(C)c2=O)n1 +Cc1ccc(F)cc1-c1ccc2cc(NC(=O)C3CCN(C)C3)ncc2c1 +CC(C)CN1C(=O)N(C)C2(NC(=O)NC2=O)c2ccccc21 +CC(=O)c1cc(Cc2ccccc2)c(O)c2ccccc12 +O=C(CCCCC(=O)Nc1cc2c(Nc3ccc(Cl)c(C(F)(F)F)c3)ncnc2s1)NO +COc1ncccc1-c1nc(N2CCOCC2C)c2ccc(-c3cccc(CO)c3)nc2n1 +CC1CN(c2cc(Nc3cc(C4CC4)[nH]n3)nc(NCc3cc(-c4ccccc4)no3)n2)CCN1 +O=C(O)c1ccc(C2(NC(=O)C3CC4CC4CN3Cc3ccc(C(F)(F)F)cc3)CC2)cc1 +CC(C)Nc1cc(-n2nc(C(C)C)c3c(-n4cnc(-c5cccnc5)c4)ccnc32)ccc1C(N)=O +COc1ccc(-c2cnoc2-c2cc(OC)c(OC)c(OC)c2)cc1 +CC(CO)(CO)n1cc(C(=O)c2cncc(NC(=O)c3cccc(OC(F)(F)F)c3)c2)c2cncnc21 +COCC(c1ccc(Cl)c(Cl)c1)n1c(C(=O)OC)cnc1S +CN1CCC(Nc2cnc3ccc(C#CCNC(=O)c4cccn(C(CO)c5ccc(F)c(F)c5)c4=O)cc3n2)CC1 +O=C(Cc1ccc(Cl)c(Cl)c1)Nc1ccc(S(=O)(=O)O)cc1 +Cc1c(C)c2ccc(OCC(=O)NN3C(=O)CSC3c3ccc(Cl)cc3)cc2oc1=O +O=C(O)C1CCC(OCC2CC(F)CN2C(=O)Cc2ccc(Nc3nc4cc(F)ccc4s3)c(Cl)c2)CC1 +O=C(CCCN1CCN(c2noc3ccccc23)CC1)c1ccc(F)cc1 +CCOC(=O)C1CC12C(=O)Nc1ccc(-c3cccn3C)cc12 +O=C(Nc1cccc(O)c1)c1cccc(S(=O)(=O)Nc2cccc(O)c2)c1 +O=C(CCc1cccc(Cl)c1Cl)NC(Cc1ccccc1)C(=O)CCl +N#Cc1ccc(CC(=O)Nc2cc(C(=O)c3cn(C4COC4)c4ccncc34)ccn2)cc1C(F)(F)F +CCCc1cc(Oc2ccc(Cl)c(C)c2)ccc1OCCCOc1cccc(C2SC(=O)NC2=O)c1 +CC1=C2CC3C(CCC4c5c[nH]nc5CCC43C)C2CCC2(C1)OC1CC(C)CNC1C2C +COc1cc(C(c2c(O)oc3ccccc3c2=O)c2c(O)oc3ccccc3c2=O)ccc1O +CCCCCCc1cc(Cc2ccc(Br)cc2)c(C=C2N=C(c3ccc[nH]3)C=C2OC)[nH]1 +O=S(=O)(Nc1ncns1)c1cc(F)c(Oc2cc(Cl)c(F)cc2-c2ccn[nH]2)cc1F +Cc1c(-c2ccc(Oc3ncccc3C(F)(F)F)c3[nH]ccc23)n(C)c(=O)[nH]c1=O +Cc1ccc(C(=O)Nc2ccc(F)c(C3(C)CS(=O)(=O)N(C)C(=N)N3)c2)nc1 +CC1(C)C2CC=C(CN3CCC(NC(=O)Nc4cc(C(F)(F)F)cc(C(F)(F)F)c4)CC3)C1C2 +CC1(C)c2cc(OCC(O)CO)c(Br)cc2C(=O)c2c1[nH]c1cc(OC(F)(F)F)ccc21 +O=C(c1cc2cc(OC3CCN(C4CC4)CC3)ccc2[nH]1)N1CCOCC1 +CC1(C)CC(O)(c2cncc(-c3cnc4c(c3)CCN4C(N)=O)c2)CCO1 +O=C(NC1CCCOC1)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +Cc1ccn2nc(C(C)Nc3ncnc(N)c3-c3cncc(OCC(F)(F)F)c3)n(-c3ccccc3)c(=O)c12 +O=S(=O)(c1ccccc1)c1nnn2c1nc(NCc1ccccc1)c1sccc12 +O=C(NC1CNCC1c1ccccc1)N1CCc2[nH]nc(-c3ccncc3)c2C1 +Cn1nc(-c2ccc(F)cc2)c(-c2ccc3nc(NC(=O)c4ccnc(F)c4)cn3n2)c1N1CCN(CC(N)=O)CC1 +COC(=O)c1ccc(C(=O)Nc2ccc(CCN3CCc4cc(OC)c(OC)cc4C3)cc2)cc1NC(=O)c1cnccn1 +OCC1OC(c2ccc(Cl)c(Cc3ccc(OCCOC4CCC4)cc3)c2)C(O)C(O)C1O +Cc1cc(C)cc(-c2cnc(-c3cccnc3)c(C(=O)NCc3ccc4c(c3)CCN4C)c2)c1 +NS(=O)(=O)c1cn(CC(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)ccc1=O +CNc1ccc(Nc2ccnc3[nH]c(=O)c4ccccc4c23)cc1 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+C=CC(C)(C)c1c2c(c(O)c3c(=O)c4ccc(O)c(O)c4oc13)C=CC(C)(C)O2 +Clc1ccc(-c2ccc(C#Cc3ccc(NCCN4CCCC4)cc3)nc2)cc1 +NC(=O)c1cc(-c2ccc(Cl)c(Cl)c2)cc2c1[nH]c1ccc(C(=O)NC3CCNC3)cc12 +CCOC(=O)c1c2c(n(C)c1COC)C(=O)C(=O)c1ccc(Br)cc1-2 +COC(=O)C1C(C=Nc2ccccc2O)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +CCC(CN(C)C)NC(=O)c1cccc2nc3ccc4c(OC)cccc4c3nc12 +CN1C(=N)N(C)C(=Cc2c[nH]c3cc(Cl)ccc23)C1=O +CCOC(=O)C(C#N)=CNc1ccc2c(c1)c1ccccc1n2CC +O=C(NCCCN1CCC(Cc2ccccc2)CC1)c1ccc(-c2ccccc2)cc1 +CN1CCN(CCNc2ccc(-c3cc4ncn(C)c(=O)c4c(NC4CC4)n3)cc2S(C)(=O)=O)CC1 +O=C1CCc2cc(C(c3ccncc3)c3cccc(F)c3)cc3c2N1CC3 +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccc(OC(F)(F)F)cc4)O2)C3=O)cn1 +COc1ccc(S(=O)(=O)n2ccc3cccc(-c4ccc(F)cc4)c32)cc1 +C1=C(Cc2ccccc2)CCN(CCC(c2csc3ccccc23)N2CCCCC2)C1 +O=C(O)C(=O)CC(=O)c1cc2ccccc2c2ccccc12 +CCOC(=O)c1cn2c(c1O)C(=O)N(Cc1ccccc1)CC2 +COc1ccc(CN2CCN(Cc3ccc(C)cc3)CC2)c(OC)c1 +COC(=O)C1C(O)C2(O)c3c(OC)cc(OC)cc3OC2(c2ccc(Br)cc2)C1c1ccccc1 +Cc1cc(C)c(CNC(=O)c2cc(-c3cnn(CCN4CCOCC4)c3)cc(N(C)C3CCNCC3)c2C)c(=O)[nH]1 +COc1ccc(-c2ccc(S(=O)(=O)NC(C(=O)O)C3CCCC(NCc4ccccc4)C3)cc2)cc1 +O=C1c2cc(-c3cn[nH]c3)ccc2-c2[nH]c3cc(-c4cn[nH]c4)ccc3c21 +CC1CN(c2ncc(C(=N)N)cc2Cl)CCN1C1CCN(Cc2ccc(Cl)cc2)CC1 +CCCCc1cc2c(=O)c(-c3ccc(C)cc3C)c(C)[nH]c2cc1OCCOc1ccccc1 +O=C(C=Cc1ccc2c(c1)CN(S(=O)(=O)Cc1ccccc1)C2)NO +Cn1cnc2cnc(NC3=NCC4(CN5CCC4CC5)O3)cc21 +CCC1NC(=O)C(CCCNC(=N)NC)NC(=O)C(C)(NC(=O)C(C)C)CCNC(=O)C(c2ccccc2)NC1=O +O=C1NC(=S)SC1=Cc1ccc(-c2cccc(C(=O)O)c2)o1 +Cc1[nH]c2nc(-c3ccccc3)nc(NCc3ccncc3)c2c1C +Oc1ccc(C=Cc2ccc(C=Cc3ccc(O)cc3)c(OCCCC(F)(F)F)c2)cc1 +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1cc2cc(Cl)ccc2[nH]1 +CC1Cn2c(=S)[nH]c3cccc(c32)CN1CC1CC1 +CCOC(=O)c1sc(NC(=O)c2cc3c(s2)CCC(C)C3)nc1C +CCOC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCc1cccc(Cl)c1 +O=C(NC1CN2CCC1CC2)c1cccc2oc(C3CC3)nc12 +Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(N4CCNCC4)nc3)cc3c2C(C)CN3C2CCOCC2)c(=O)[nH]1 +CC1CN2c3c(cc4c(N5CC(CF)OC5=O)noc4c3F)CC3(C(=O)NC(=O)NC3=O)C2C(C)O1 +CN1C(=O)CN=C(c2ccccc2F)c2c(Cl)cccc21 +CC(C)CC(CCCCn1cnc2c1NC=NCC2O)(CC(C)C)C(=O)O +CC(C)(C)n1nnnc1C(c1cccc(Nc2ccnc3cc(Cl)ccc23)c1)N1CCOCC1 +COc1ccc(-n2c3cnccc3c3cnc(Nc4ccc(N5CCNCC5)cn4)nc32)cc1 +COC(=O)CCC(=O)N(O)c1cccc(OCc2nc3ccccc3s2)c1 +CSC(=O)N1CC2(CCCCC2)CSC1=Nc1cccc2ccccc12 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)N1CCN(C)CC1 +CN(C)CC1CCC(Nc2c(C(=O)C3CCCC3)cnc3ccc(-c4cc(Cl)c(O)c(Cl)c4)cc23)CC1 +CC1CCCN1C1CCC(c2ccc(NC(=O)c3ccc(Cl)cc3)cc2)C1 +Cc1cc(C)cc(Cn2c(=O)cc(N)n(Cc3ccccc3)c2=O)c1 +Cc1ccc(-c2nnnn2CCCOc2ccc(S(=O)(=O)C3(C(=O)NO)CCOCC3)cc2)nc1 +CN1C(=O)CCc2ccc(NC(=O)NC3CC(C)(C)Oc4c(F)cccc43)cc21 +O=S(=O)(Nc1cccc(-c2nnn[nH]2)c1)c1c(Cl)cc(C(F)(F)F)cc1Cl +CC1(C)C(=O)N=C2c3ccccc3C(=O)C(=O)C21 +NC(CC(=O)N1CCCNC(=O)C1Cc1cnccn1)Cc1cc(F)c(F)cc1F +CCC1CC(=O)NN=C1c1ccc2nc(-c3ccc(OCCN4CC5CCC4C5)cc3)oc2c1 +NC(=O)c1ccc(N2CCN(CCCCc3c[nH]c4ccc(C(N)=O)cc34)CC2)cc1 +C=CC[N+]1(C)CCC23c4c5ccc(O)c4OC2C(=O)CCC3(O)C1C5 +Clc1cccc2sc(NC3=NCC4(CN5CCC4CC5)N3)nc12 +COC(=O)C1C2CCC3CCC1N(CC2=Cc1ccc(-c2ccc(I)cc2)cc1)C3 +C=C(c1nc2ccccc2s1)C1CCN(CCc2ccc(OC)cc2)CC1 +O=C(NC1CCCC1)C(c1ccc(F)cc1)N(Cc1ccc(F)cc1)C(=O)CCl +CCOC(=O)C=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1 +CN1CCN(c2cccc(Nc3nc4c(Nc5ccccc5CN(C)S(C)(=O)=O)cccn4n3)c2)CC1 +COC(=O)CSc1nnc(Cc2c(NC(=O)c3ccccc3)sc3c2CCCC3)n1NC(C)=O +CN1CCC(COC(=O)c2cc(Cl)c(N)c3c2OCCO3)CC1 +CC(=O)N1CCc2cc(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)ccc21 +CN(c1ccnc(Nc2cccc(S(C)(=O)=O)c2)n1)c1c(Cl)ccc2c1OCO2 +C=CCn1c(-c2cc3c(cc2C=C)OCO3)cc2ccc(OC)c(OC)c2c1=O +CC(C)C(C(=O)Nc1ccc(C(=O)NO)cc1)c1ccccc1 +CC(C)CCCSc1c(C#N)c(C(F)(F)F)nn1-c1ccc(S(C)(=O)=O)cn1 +CC(Oc1ccccc1)C(=O)N(Cc1cccc(Cl)c1)CC1CCCN1 +O=C1c2ccccc2NC(c2ccccc2Cl)N1N=C1CCCCCC1 +N=C(N)c1cccc(N2CC(O)CN(CC3CCN(Cc4ccccc4)CC3)C2=O)c1 +O=C(Nc1ccc2c(c1)OC(F)(F)O2)c1ccccc1NCc1ccnc(NCCO)c1 +c1ccc2sc(-c3ccc(OCCCCNc4c5c(nc6ccccc46)CCCC5)cc3)nc2c1 +CC1(O)CC(c2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)nccn23)C1 +C=CC12c3c4ccc(O)c3OC1C(=O)CCC2(O)C(N(C)CC1CC1)C4 +Cc1cc(CN2CCN(c3c(Cl)cnc4[nH]c(-c5ccnn5C)nc34)CC2)no1 +Cn1cc2c(nc(NCc3ccc(Cl)cc3)n3nc(-c4ccco4)nc23)n1 +N#CC(=C(c1ccccc1)c1ccc(OCCN2CCOCC2)cc1)c1ccccc1 +O=C(NO)c1ccc2c(c1)CC(NS(=O)(=O)c1ccc(F)cc1F)CC2 +CCC(NC(C)(C)CC(N)=O)c1ccc(Cl)c(C(=O)c2cccnc2)c1F +C#CCCCC(=O)c1cc(C(C)(C)C)c2c(c1)C(C)(C)CO2 +CC(C)CNC(=O)COc1cccc(CC(=O)Nc2ccc(CCCCc3nnc(NC(=O)Cc4ccccc4)s3)nn2)c1 +CN1C(CC(=O)c2ccccc2)CCCC1CC(OC(=O)c1ccccc1)c1ccccc1 +[C-]#[N+]c1c(F)ccc(C2CN3CCN(C(=O)Cc4ccnc(-n5cnnn5)c4)CC3CO2)c1C +CC(=NO)c1ccc(Nc2cc(C=Cc3ccc([N+](=O)[O-])o3)nc3ccccc23)cc1 +COc1ccccc1C(=O)NCCNC(=O)c1ccc(-c2cccc3[nH]nc(N)c23)cc1 +C=Cc1cn(-c2ccc(C(N)=O)c(NC3CCC(O)CC3)c2)c2nccc(-c3cnc4ccccc4c3)c12 +Cc1nc(Cl)c(-c2cc(C(=O)N3CC(c4ccc(C#N)cc4)C3)ccc2C)[nH]1 +CC(C)(NS(C)(=O)=O)C(NC(=O)c1ccc(-c2cc3cc(F)ccc3o2)cc1)C(=O)NO +Cc1ccc(C(=O)NCCO)cc1-n1cnc(SCc2ccc(F)cc2F)c(Cl)c1=O +CN(C)S(=O)(=O)Nc1ccc2c(c1)C(c1ccccc1Cl)=Nc1c[nH]nc1N2 +CC1CN2CCCC2C(=O)NC(C(=O)O)CSSCC(NC(=O)C23CC4CC(CC(C4)C2)C3)C(=O)N1 +COC(=O)CCC(=O)NC(C)C(=O)NC(C)C(=O)N1CCCC1C(=O)NC(C(=O)OC)C(C)C +COc1ccc(-c2ccc(-c3ccncc3)o2)cc1OC1CCCC1 +COc1cc2ncc3c(N)nc(-c4cncc(OCC(N)Cc5ccccc5)c4)cc3c2cc1OC +Cn1c(C(=O)c2ccc(Cl)cc2)cnc1CCCCN1CCCCC1 +C[N+](C)(C)c1ccc(CNC(=O)c2cc3cc(O)ccc3n2Cc2cccc(C(=N)N)c2)cc1 +Cc1c(C)c2c(c(C)c1N)CC(C)(CNCc1ccccc1)O2 +O=C(O)C1=C(C(=O)Nc2ccc(-c3ccccc3)cc2)CCC1 +CC(=O)Nc1ccc(Oc2ccc3c(c2)CCN(C2CCC2)CC3)nc1 +CC(C)Oc1ccc(S(=O)(=O)c2ccc(NC(=O)C=Cc3cccnc3)cc2)cc1 +CN(CCCNc1ccnc2cc(Cl)ccc12)C(=O)COc1ccccc1 +N#CCC1(n2cc(C(N)=O)c(Nc3ccc(F)cc3)n2)CCC(Nc2cccc(Cl)c2)CC1 +O=C(NCCNS(=O)(=O)c1cccnc1)c1cccc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +Clc1ccc2c(N(CCCN3CCCCC3)C(=NCCCN3CCCCC3)c3ccccc3)ccnc2c1 +CCCN(CCC1CCC(NS(=O)(=O)c2ccc(-c3ccccc3)cc2)CC1)C1CCc2nc(N)sc2C1 +O=C(NC1CCN(Cc2ccc(OCCCN(C3CC3)C3CC3)c(F)c2)CC1)c1cc(=O)c2ccc(F)cc2o1 +Nc1cc(C(=O)N2CCCCC2)cc2nc(-c3ccco3)nn12 +COc1ccccc1-c1cc(Cl)cc(C(CC(=O)O)c2nnc(C)o2)c1 +O=C(Nc1ccc(-c2ccc(NS(=O)(=O)c3ccccc3)cc2)cc1)C1CN2CCC1CC2 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+O=c1[nH]c(O)c(Cc2ccc(OCC3CCCCC3)c(Cl)c2)s1 +CCC(C)(C)c1ccc(S(=O)(=O)Nc2ncnc(OCCOc3ncc(Br)cn3)c2-c2ccc(C)cc2)cc1 +CCCCC1(CC)CS(=O)(=O)c2cc(CP(=O)(O)O)c(OC)cc2C(c2ccccc2)N1 +CCC1C(=O)N(C)c2cnc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC3CCCC3)nc2N1C1CCCC1 +CC1CCC(Cn2c(N3CCCC3C(=O)N(C)C)nc3cc(-c4noc(=O)[nH]4)nc(-c4cncc(Cl)c4)c32)CC1 +CC(C)(C)CCNC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +CNCc1cc(-c2ccccc2)n(S(=O)(=O)c2cccs2)c1 +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3ccc(N(CCN4CCCC4)C(=O)c4ccccc4)cc3)nnc2c1 +Cc1nc2cccnc2n2c(-c3cc(OCC4(C)COC4)ccc3Cl)nnc12 +COc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COCC(F)(F)F)c2)c1F +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1c(F)cccc1C(F)(F)F +CCCCNC(=O)N1Cc2n[nH]c(NC(=O)Cc3ccccc3F)c2C1 +CONC(=O)c1cccc(Oc2cc(CN)cc(C(F)(F)F)n2)c1 +COc1cc(C(F)(F)F)ccc1-c1ncc(F)c2cc(S(=O)(=O)Nc3nccs3)ccc12 +CC(C)(C)C1CCC2(CC1)CN(c1ccccc1Cl)C(=O)N2Cc1ccc(C(=O)Nc2nn[nH]n2)cc1 +CN(c1c2c(c(O)c3ncccc13)C(=O)N(Cc1ccc(F)c(Cl)c1F)C2)S(C)(=O)=O +CCc1cc(CCC(=O)c2sc(CC)c3c2CCC(C)(C)C3)cc(C)c1OCC(O)CNC(=O)CO +CNC(=O)c1cnc(Nc2ccc3ncsc3c2)cc1NCCO +O=C1C=C(NCCCCCCCCCC[P+](c2ccccc2)(c2ccccc2)c2ccccc2)C(=O)c2ccccc21 +CCNc1nc2cc(F)c(OC)cc2cc1Cc1c(=O)[nH]c(CC)c2cc(OC)c(OC)cc12 +COc1ccc(-c2cc(-c3ccc4nccn4c3)cnc2N)cn1 +Cc1ncc(C)n2nc(CCc3nc(-c4cscn4)cn3C)nc12 +CS(=O)(=O)C(C(=O)NCCS(N)(=O)=O)c1nc2ccc(-c3ccc(C(N)=O)cc3)cc2s1 +O=S(=O)(c1ccccc1)N(CCN1CCOCC1)c1sc2ccccc2c1Br +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)NCCc1ccncc1 +COc1cc(N2CCOCC2)ccc1Nc1nc2c(c(Nc3ccccc3S(=O)(=O)N(C)C)n1)CCN2 +COCc1cn(C2=NCC(=O)N3CCc4c(cccc4C4CC4)C3=C2)cn1 +Cc1cc(C#N)cc2nc(-c3ccc(NC(=O)COC4CCN(C(=O)OC(C)C)CC4)cc3)oc12 +N#CC(c1cccnc1)N1CCN(C(=O)C(c2ccccc2)c2ccccc2)CC1 +COc1cccc(NC(=O)N2CCC(c3nc(-c4ccc5ccccc5n4)no3)CC2)c1 +COc1ccc(-c2csc(C=Cc3cccc(C(CCc4ccccc4C(C)(C)O)SCC4(CC(=O)O)CC4)c3)n2)cc1 +OCC1OC(n2c(Nc3ccccc3)nc3c(Nc4ccccc4)ncnc32)C(O)C1O +O=C(NCc1nc(Cc2ccccc2)cs1)C(O)C(O)C(=O)N1CCCC1c1ccccc1 +COc1cc(-c2ccc3ncc(S(C)(=O)=O)c(Nc4ccc(CN(C)C)cc4)c3n2)cc(Cl)c1O +CC(C)Oc1cnc2c(Nc3cc(Cl)c(F)c(C4(CF)N=C(N)OC5CC54)c3)nccc2n1 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+O=c1c2cnc3ccccc3c2ncn1CCCN1CCN(c2cccc(Cl)c2)CC1 +N#CC(Cc1ccc(C2CCCCC2)cc1)NC(=O)C1NC2CCC1C2 +COc1ccc(S(=O)(=O)C(C)(CC=Cc2ccccc2)C(=O)NO)cc1 +O=C(c1cccnc1)N1CCN(c2cnc3ccn(S(=O)(=O)c4cccc5nonc45)c3c2)CC1 +COc1ccc(C)cc1NC(=O)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CSc1ccc(CC2CCN(C3(C)CCN(C(=O)c4c(C)cccc4C)CC3)CC2)cc1 +COc1cc2c(NC3CCN(C(C)C)CC3)nc(N3CCCN(C(C)C)CC3)nc2cc1OCCCN1CCCCC1 +CNCC#Cc1ccc2c(c1)CCn1c-2cc(OCC2COc3ncccc3O2)nc1=O +O=C1CC(C(=O)Nc2cc(-c3cccc(OC(F)(F)F)c3)n(CCc3ccccc3)n2)CN1 +N#Cc1ccc2nc(Nc3ccc(Oc4ncccc4C(F)(F)F)cc3)[nH]c2c1 +Cc1ncsc1CNc1nc(-n2ncc3ccncc32)nc(N)c1Br +Cc1ccc(C(=O)Nc2ccc3c(c2)C2(CCOC(N)=N2)c2cc(C4=CCCOC4)ncc2O3)nc1 +COc1ccc(Cn2cnc3c2CC(C(=O)O)N(C(=O)C(c2ccccc2)c2ccccc2)C3)cc1F +CNC(=O)c1cc2cc(Nc3nccc(-c4cn(C)cn4)n3)cc(OC)c2[nH]1 +CCCCCCCCCCCCCCCCC(CC(=O)O)C(=O)NC(C(=O)NC)C(C)(C)C +CC(=O)NCC1CN(c2ccc(-c3ccc(CNCc4ccncc4)cc3)c(F)c2)C(=O)O1 +CC(=O)N1CCC(C)(N2CCc3c(-c4cnc(N)nc4)nc(N4CCOCC4C)nc32)C1 +Cc1ccccc1C(=O)C1CCN(c2ccc(C(=O)NCC(O)c3ccncc3)nn2)CC1 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+CN1CCCN(c2nccnc2C2CN(c3ccc4ccccc4n3)C2)CC1 +NS(=O)(=O)c1cccc(NC(=[Se])NC(=O)c2ccccc2)c1 +CC(=O)NCCc1c[nH]c2ccc(OC(=O)NCCCCCCCCNc3c4c(nc5ccccc35)CCCC4)cc12 +C=CC(=O)Nc1cccc(Nc2nc(Nc3ccc(N4CCN(S(C)(=O)=O)CC4)cc3OC)ncc2C(F)(F)F)c1 +O=C(Nc1cccc(OCCCN2CCOCC2)c1)Nc1ccc2c(c1)OCO2 +COC(C1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1)C1CCCN1C +O=C1OC(CO)(COC(=O)c2ccc([N+](=O)[O-])cc2)CC1=CC1CCCCC1 +O=C(O)CC1CCC(NC(=O)C(C2CCCCC2)n2c(-c3ccc(Cl)cc3)nc3cc(F)c(F)cc32)CC1 +O=C(Nc1ccc2c(c1)OCO2)c1scnc1CCc1ccncc1 +CCC(=O)Nc1cc(-c2ccccc2)nc(-c2ccccc2)n1 +CC(C)c1cccc(C(C)C)c1NC(=O)NCC(NCc1ccccn1)c1ccccc1 +COc1cc2ncnc(N3CCC(Oc4ccccc4C)C3)c2cc1OC +CNC(Cc1ccccc1)C(=O)N1CCCC1C(=O)NC(CCCN=C(N)N)C(=O)c1nc2ccc(C(N)=O)cc2s1 +COc1ccccc1OCCCN1CCC(c2noc3cc(F)ccc23)CC1 +COCCN(C)C(=O)c1ncccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(-c2ccc(C)s2)cc1 +CN1C(=O)C(=C(C#N)C#N)c2cc(S(=O)(=O)N3CCCC3COc3ccccc3)ccc21 +O=S(=O)(NC1(c2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)CCC1)c1ccc(F)cc1 +N=C(N)c1cc2cc(-c3cccc(-c4ccccc4)c3O)[nH]c2cc1F 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+COC1=CC(=O)c2c(COc3ccccc3[N+](=O)[O-])c(C)n(C)c2C1=O +Cc1c(OCCN2CCOCC2)cn2ncc(C#N)c(Nc3ccc(Oc4ccccc4)cc3)c12 +CNCCC1Cc2ccccc2C2(CCN(Cc3ccccc3)CC2)O1 +COc1ccccc1CNc1ncnc2c1sc1nc(N3CCOCC3)c3c(c12)CC(C)(C)OC3 +O=C(OC1CNC(C#Cc2cc3ncnc(Nc4ccc(OCc5cccc(F)c5)c(Cl)c4)c3s2)C1)N1CCNCC1 +Cc1ccccc1C=CC(=O)NC12CCC(=O)C3Oc4c(O)ccc5c4C31CCN(C)C2C5 +CCCCCCCCCCCCCCCCCCNC(=O)N1CCN(C(=O)Nc2ccc(Cc3noc(=O)[nH]3)cc2)CC1 +CCn1ncc(NC(=O)c2nc(-c3c(F)cccc3F)sc2N)c1N1CCC(N)C(F)CC1 +CS(=O)(=O)c1cc(Br)c2c(c1)c1c(n2Cc2ccc3ccc(Cl)cc3n2)C(CC(=O)O)CC1 +CCOc1nc(NC(=O)Cc2ccc(C)cc2)cc(N)c1C#N +CC1(C(=O)O)CCCCC1Nc1nc(-c2c[nH]c3ncc(Cl)cc23)ncc1F +O=C(Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c2c1OC1(CCS(=O)(=O)CC1)O2 +Cc1cccc(-c2cc(-c3ccco3)nc(N)c2C#N)c1 +CN(C)CCn1c2c(c3ccccc3c1=O)C(=O)c1cc(O)ccc1-2 +COC1CCC2(C)C3CCC4C(=CCC5C(C)(C)C(OC(=O)CN)CCC45C)CC3(C)CCC2C1(C)C +N#Cc1ccc2c(c1)CN(CCC1CC1CNC(=O)c1cc3ccccc3[nH]1)CC2 +O=C(c1ccc(OCCCN2CC3CC2CN3C(=O)c2ccco2)cc1)C1CC1 +Cc1ccc(SCC(=O)Nc2cc([N+](=O)[O-])ccc2O)cc1 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+O=C(N1CC(O)CCC1Cc1ccccc1)n1ncc(C(O)(c2ccc(F)cc2)c2ccc(F)cc2)n1 +COC(C)C(=O)N(c1ccccc1F)C1CCN(CCc2cccs2)CC1C +CCN(CC)CCCn1c(=C2C(=O)Nc3ccc(F)cc32)sc(=Cc2ccc3c(c2)OCO3)c1=O +CCOc1ccc(Cc2cc(C3OC(CO)C(O)C(O)C3O)c(OCC3CNC3)cc2Cl)cc1 +COc1cc(CC(C(C)=O)C(=O)NCCCCCCNc2c3c(nc4ccccc24)CCCC3)ccc1O +CCCc1ccc(-n2[nH]c3c(cnc4cc(C)ccc43)c2=O)s1 +O=C1OCC(c2ccccc2)N1c1ccn2ncc(-c3ccc(-c4ncc[nH]4)cc3)c2n1 +CSc1c(Cl)nc(-c2ccc(NC(=O)Nc3cccnc3)cc2)nc1N1CCOCC1 +CSC(=S)N1CC2(CCCCC2)COC1=Nc1ccc(C#N)c2c1CCCC2 +Cc1c(Oc2cnc(C(=O)N3CC(C)(O)C3)cn2)ccc2c1B(O)OC2 +N#Cc1ccc(NC(=O)Nc2cccc(-c3cccc(N4CCCC4)n3)c2)cc1 +CC(C)(C)NC(=O)N1CCn2c(c(C(N)=O)c(-c3cccc(F)c3)c2C2CC2)C1 +CC1(C)CC(c2ccccc2)=NN(C(=O)c2ccc(Cl)c(Cl)c2)C1 +COc1ccc(-c2[nH]nc3c2C(=O)c2c(NC(=O)CN4CCN(C(=N)N)CC4)cccc2-3)cc1 +CCOC(=O)c1c[nH]c2ncnc(-c3cccc(O)c3)c12 +COc1ccc(-n2nnc(C(=O)Nc3c(C)n(C)n(C4CCCCC4)c3=O)c2C)c(Cl)c1 +COc1ccccc1-c1cccc(S(=O)(=O)c2cc(C(=N)N)sc2SC)c1 +CC(C)(C)Nc1c(Nc2ccnc(Nc3ccc4c(c3)CCO4)n2)c(=O)c1=O +O=C(Cc1cccc2ccccc12)N1CCC(CNCCCCN2CCCCC2)CC1 +CNC(=O)C(NC(=O)C(CCCCCCCCCCCCCCO)CC(=O)NO)C(C)(C)C +C=C1C(=CC=C2CCCC3(C)C2CCC3C(C)CC2OC(=O)C(=C)C23CCCC3)CC(O)CC1O +O=C(O)c1ccc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1Cl +CNC(=O)CN1CN(c2ccccc2)C2(CCN(C(=O)OCc3cc4c(cc3Cl)OCO4)CC2)C1=O +O=C(Nc1ccccc1)NC1C(=O)N(CC23CC4CC(CC(C4)C2)C3)c2ccccc2N(C2CCCCC2)C1=O +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2ccnc(F)c2)c1 +CC(=O)NC1C(C(O)C(O)CO)OC(C(=O)O)=CC1N(CCCC(=O)N1CCNCC1)C(=N)N +CC1(C)C(=O)Nc2nc(-n3nc(Cc4ccccc4F)c4cc(F)ccc43)nc(I)c21 +O=C(Nc1ccc(C2CNCCO2)cc1F)c1ccn(-c2ccc(F)cc2)n1 +CCN1CCN(Cc2ccc(-c3ccc4c(Nc5cc(OC)c(Cl)cc5Cl)c(C#N)cnc4c3)cc2)CC1 +COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)c4c(OCc5cccc(Br)c5)cccc4o3)c2c1 +O=C(c1cccc(N(Cc2ccccc2)c2ccc([N+](=O)[O-])cc2)c1)N1CCCC1 +Cc1ccc(N(C(=O)OCC2CCC(COCC(=O)O)CC2)c2cccc(F)c2)s1 +CCOc1cc(C)c(Nc2ccnc(N3CCN(c4ccc(OC)cc4)C(C)(C)C3)n2)cc1C(C)C +Cc1cc(C(=O)c2ccccc2C)ccc1Nc1ccccc1N +Cc1nc(NC(C)c2cccc(-c3cnn(C)c3)c2)cc(-c2ccc3ncsc3c2)n1 +CSc1cc(F)cc(C(CO)NC(=O)c2ccc(-c3nc(C4CCOCC4)cnc3N)cc2F)c1 +CCOc1cccc(F)c1CCNC(=S)Nc1ccc(C)cn1 +COCC(C)(C)n1cc(C(=O)c2cncc(NC(=O)Cn3cc(C4CC4)nn3)c2)c2cnc(N)nc21 +FC1(F)Oc2ccc(Nc3nnc(-c4cccnc4NCc4ccccn4)o3)cc2O1 +CCC(C1=C(CCN(C)C)Cc2ccccc21)c1ccccn1 +CCCNC(=O)OCC1OC(n2cnc3c(NC4CCCC4)nc(Cl)nc32)C(C)(O)C1O +Cc1ccc2c(-c3nnc(SCCN4CCc5cc6nc(C)oc6c(C)c5CC4)n3C)cccc2n1 +O=C(O)CCc1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)cc(Cc2ccncc2)c1 +CN(C(=O)C(C#N)=Cc1cn(CC(=O)O)c2cc(Cl)ccc12)c1ccccc1 +COc1ccc(OC)c(-c2cc(NC(C)=O)nc(-c3cc(OC)ccc3OC)c2)c1 +CNC(=O)c1cnc(N)c2cc(-c3ccccc3)sc12 +O=c1cc(-c2ccccc2)n(-c2cccc(-c3ccccc3)c2)cc1O +Cn1cc(C(=O)CCCCCCCc2ccccc2)cc1C=CC(=O)NO +CC(=O)c1ccc(Cl)cc1OCC(=O)Nc1ccccc1C(=O)O +Cc1ccccc1-c1ccccc1CN(C(=O)c1ccc(-c2ccc(C#N)cc2)o1)c1ccc(N2CCNCC2)cc1 +O=C(c1ccnc(Cl)c1)N1CC2(CCN(CC=Cc3ccc(Cl)cc3)CC2)c2cc(F)ccc21 +COc1ccc2c(c1)CC(CCN(C)C)=C2C(C)c1cnccn1 +Cc1ccc(NC(=O)c2sc3ccccc3c2Cl)c(C(=O)Nc2ccc(Br)cc2)c1 +CCN1CCCC(CN2CCN(C(=O)Nc3ccc(Cl)c(Cl)c3)CC2)C1 +COC(c1ccc(F)cc1)(c1ccc(F)cc1)c1ccc(C(=O)NCCCCCCC(=O)NO)cc1 +O=C(NCc1cn(-c2ccccc2)c2cc(Cl)ccc2c1=O)c1ccc(N2CCOCC2)nc1 +CCC(=O)N1CCC(N2C(=O)N(c3ccccc3C)Cc3cnc(Nc4ccc(N5CCN(C)CC5)c(C)c4)nc32)C1 +CCC(NC(=O)c1c([S+]([O-])CC(=O)N(C)C)c(-c2ccccc2)nc2ccccc12)c1ccccc1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(N(CC)CC)n3)C2)cc1 +CCC1CCCCN1CCCOc1cc2ncc(C#N)c(Nc3ccc(Sc4nc(C)c(C)n4CC)c(Cl)c3)c2cc1OC +N#CC1CCCN1C(=O)CNC(=O)c1ccnc2cnccc12 +O=C(Nc1ccc(C(F)(F)F)cc1)c1csc(Nc2c(Cl)cncc2Cl)n1 +CC(C)n1ncc2c(C(=O)Nc3cc(S(N)(=O)=O)ccc3F)cc(-c3cccs3)nc21 +N#CCC1(n2cc(C(N)=O)c(Nc3ccccc3)n2)CCC(C(=O)NCC(F)(F)F)CC1 +CCCn1c(=O)c2[nH]c(-c3cnn(CC4CC(=O)N(c5cccc(F)c5)C4)c3)nc2n(CCC)c1=O +O=C(O)C(Cc1ccc(OCc2c(Cl)cccc2Cl)cc1)NC(=O)C1OCOC1C(=O)Nc1c(Cl)cccc1Cl +CCC(=O)C1C2CCC(CC1c1ccc(I)c(F)c1)N2 +CC1CN(c2ccc(-n3cnc4c(-c5ccc(F)cc5)cccc4c3=O)cn2)CC(C)O1 +N#CC1CCN(CCC2CCOCC2)CC1n1cc(C(N)=O)c(Nc2ccc(F)cc2)n1 +NC(Cc1cc2ccccc2cc1CP(=O)(O)O)C(=O)O +O=C1OC(CN2CCC(O)(c3ccc4c(c3)OCO4)CC2)CN1c1ccc(F)cc1 +Cc1cc(C)cc(C(F)=C2CCC(NC(=O)c3ccnc4ccccc34)CC2Cc2ccccc2)c1 +CCNC(=O)Nc1nc2cc(-c3cncnc3)ccc2[nH]1 +O=C(OCCCCN1CCC(c2ccccc2)CC1)C1(c2ccccc2)CCCC1 +COc1ccc(OC)c(C=Cc2cc(OC)c(O)c(OC)c2)c1 +CCC(CC(=O)O)c1cccc(OCc2ccc(-c3cc(OC)ccc3F)c(C(C)(C)C)c2)c1 +CN(C)CCn1cc(NC(=O)c2cccc(-n3cc(NC(=O)Nc4ccccc4Cl)cn3)c2)cn1 +Cc1cc(COc2c(C)cccc2-c2csc(N3CCC4(C(=O)O)CC4C3)n2)cc2c1CN(CC1COCCO1)CC2 +CC1OCCC1OC(=O)NC(CSc1ccccc1)C(O)CN1CC2CCSC2CC1C(=O)NC(C)(C)C +CCC(O)(CC)C(C)Oc1ncc(C(F)(F)F)cc1-c1ccc(S(C)(=O)=O)cc1 +CC(CCNCC12CC3CC(CC(C3)C1)C2)Nc1c(F)cnc2ccccc12 +O=C(Nc1ccc2c(c1)S(=O)(=O)C=C2)c1cc(Cl)ccc1OCCN1CCOCC1 +CNc1ccc(C#CCC(NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N(C)C2CCCC2)cn1 +Cc1c(NC2CC2)nc(C2CC2C)nc1N1CCCCCC1 +COc1cnc2ccc(C(C)(F)c3nnc4c(F)cc(-c5cc(C)no5)cn34)cc2c1 +CC(C)(C#N)Cn1cc(-c2nc(C3(c4ccc(-c5cnc(N)nc5)nc4)CCC3)no2)cn1 +O=C(Nc1ccc(C2CCCNC2)cc1)c1ccc(Cl)nc1 +CCCCS(=O)(=O)N1CCN(Cc2c3c(nc4ccccc24)-c2cc4c(c(=O)n2C3)COC(=O)C4(O)CC)CC1 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(C(C)(C)C)on4)c3)c2cc1OCCN1CCOCC1 +O=C(CCCCCS)Nc1cc(CCC(=O)c2c(O)cc(O)cc2OC2OC(CO)C(O)C(O)C2O)ccc1O +CCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CC4CC3C4)n2)cc1C1CC1 +Cc1cn(-c2ccc3n(c2=O)CCN(CC2CCC(c4ccc(Cl)c(Cl)c4)O2)C3=O)cn1 +CCNC(=O)C1OC(n2cnc3c(NCC4CC5CC4C4OC54)ncnc32)C(O)C1O +O=C(O)c1cccc(N2CCc3cccc(C(=O)Nc4nc5ccccc5s4)c3C2)n1 +CC1CN(CCc2ccccc2)CCC1N(C(=O)c1ccco1)c1ccccc1Cl +CCn1nc2c(c1C)-c1nc(Nc3ccc(CN(C)C)cc3)ncc1CC2 +O=C(NC12CCCC(C#Cc3ccccn3)(CC1)C2)c1ccc(F)cn1 +COc1ccc(C(=O)Nc2ncncc2Cl)c2cc(C(C)=O)oc12 +COC(=O)c1ccc(-c2ccc(OC3OC(CO)C(O)C(O)C3O)cc2)cc1 +COc1ccc(-c2nsc3c2NC(=O)CC3c2ccc3c(c2)OCCO3)cc1 +CCNC(=O)C(C)c1ccc(OC2CCN(c3ccnc(OCc4ccccc4)c3)C2)cc1 +Cn1c(C(=O)NC2CCCC2)nc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1-c1cn[nH]c1 +Cc1cn(-c2ccc3n(c2=O)CCN(C2CCCC2Oc2ccccc2C(F)(F)F)C3=O)cn1 +Nc1cc2n[nH]c(=O)n2c2cc(-c3ccoc3)ccc12 +CN1CCN(CCNc2nc(Nc3ccc(F)c(Cl)c3)nc3cccnc23)CC1 +CCC1COc2cc3[nH]c(=O)cc(C(F)(F)F)c3cc2N1CC +CCc1cc2c(cc1NC(=O)N1CCC(C(C)(C)O)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +Cc1cccc(C)c1-c1cc(C)c2nc(Nc3cccc(C(=O)NCCCN4CCN(C)CC4)c3)nnc2c1 +Cc1ccc(C(=O)NCc2ccc(C(C)(C)C)cc2)cc1Nc1ncnc2cnc(N3CCCCC3)nc12 +O=C(NCCCc1ccccc1)C12CC3CC(CC(C3)C1)C2 +COc1cc2nccc(Oc3ccc(NC(=O)c4cc(-c5cccs5)cn(-c5ccccc5)c4=O)nc3)c2cc1OC +CC(C)(Cc1ccc(F)cc1C#N)C1OCC(CC=CCCC(=O)O)C(c2cccnc2)O1 +O=C1N(Cc2cccc(-n3nccn3)c2)CCCC12CCN(c1cnc3ccccc3n1)CC2 +O=C(NCC(NS(=O)(=O)c1ccccc1)C(=O)O)c1cc2cc(CCC3CCNCC3)sc2s1 +NC(=O)c1cccc2[nH]n(C3CCN(Cc4ccco4)CC3)c(=O)c12 +CCOc1ccc(-n2c(C)c3c(C)nnc(NCc4ccc(OC)cc4)c3c2C)cc1 +C=CCn1c(O)c(N=NC(S)=Nc2ccccc2F)c2ccccc21 +Cc1c(-c2ccc(O)cc2)n(Cc2ccc(OCCN(C(C)C)C(C)C)cc2)c2ccc(O)cc12 +CCn1c(NC(=O)c2ccc3cc4n(c3c2)C(C)CCNC4=O)nc2ccccc21 +COc1cc(C(=O)NN=Cc2ccc(OC)c(CN3CCN(c4ccc(F)cc4)CC3)c2)ccc1O +O=c1[nH]c(N2CCOCC2)nc(NCCNCCO)c1-c1ccc2ccccc2n1 +OCc1cc(C(O)CNCCCCCCOCCCCc2ccccc2)ccc1O +CCN(CC)C(=O)c1ccc(N(c2cccc(O)c2)C2CCN(C)CC2)cc1 +Nc1ccc(-c2ccc3cc(NC(=O)C4CC4)ncc3c2)cn1 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+O=C(NNc1ccc(N(CCCl)CCCl)cc1)Nc1cc(-c2ccccc2)nc2cc3c(cc12)OCO3 +NS(=O)(=O)c1ccc(NC(=O)Nc2ccc(Cl)cc2[N+](=O)[O-])cc1 +Cc1ccc(Nc2cnc(-c3ccccc3)c(F)c2)c(C(=O)O)c1 +Cc1ncc(F)cc1C1CCCN1c1ccn2ncc(C(=O)NC3CCC(O)C3)c2n1 +CC1(C(=O)O)CCc2ccc(OCCCOc3ccc(OCC4CC4)cc3Cl)cc2O1 +CNc1nn2c(C)cc(C)nc2c1S(=O)(=O)c1cccc(Cl)c1 +COc1c(Cl)c2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1C(NC(=S)Nc1cccnc1)CC2 +Cc1cccc(N2CCCCC2)c1CNC(N)=NC(=O)c1ccc(CC(N)C(=O)O)cc1 +CCN(CC)C(=O)Cc1c(-c2ccc(OCc3ccccc3C(F)(F)F)cc2)nn2c(C)cc(C)nc12 +COc1cc(C#CCC[N+]23CCC(CC2)CC3)cc(OC)c1OC +COc1ccc(-n2c(Sc3nnc(N)s3)nc3ccc(Cl)cc3c2=O)cc1 +CCCCNC(=O)c1ccc2c(c1)N=C(c1ccccc1Cl)c1ccccc1S2 +Cc1sc(NC(Cc2ccccc2)(c2cc(F)cc(OC(F)(F)C(F)F)c2)c2ccc(Cl)cn2)nc1C(F)(F)F +Cc1nnc(Nc2cc(C(=O)NC3CC3)ccc2Cl)c2cnn(-c3ccc(F)cc3)c12 +CCCCCCCN(CCc1ccc(OC(C)(CC)C(=O)O)cc1)c1nc2ccccc2o1 +NS(=O)(=O)c1ccc(-n2nc(CCCNC(=O)Nc3ccc(C(F)(F)F)cc3)cc2-c2ccccc2)cc1 +Cc1ccc(-n2nccn2)c(C(=O)N2C3CCC2C(COc2nc4ccccc4nc2C(F)(F)F)C3)c1 +CCCCC(NC(=O)CNC(=O)c1ccc(S(N)(=O)=O)cc1)C(=O)O 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+N#Cc1cc(-c2ccc3c(c2)NC(=O)CO3)n(-c2ccc(F)cc2)n1 +Nc1nc(N2CCNCC2)c2oc3ccc(Cl)c(Cl)c3c2n1 +COCCN(C)c1nc2cc(-c3noc(=O)[nH]3)nc(-c3cncc(Cl)c3)c2n1CC1CCC(C)CC1 +CCCCCC[N+]1(C)C2CCC1CC(CC(C#N)(c1ccccc1)c1ccccc1)C2 +O=C(C(NS(=O)(=O)c1cnccc1NC(CO)Cc1ccccc1)c1ccc2ccccc2c1)N1CCC(CCF)CC1 +CCC(C(C)C(C)(C)O)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COC(=O)c1ccc(Nc2nc3ccc(C(=O)N(CCC(C)C)CCC(C)C)cc3n2CCCN2CCCCC2)cc1 +CN(C)CCNS(=O)(=O)c1ccc(-c2ccnc3[nH]ccc23)cc1 +O=C(Nc1cc(Cl)ccc1-c1ccc(F)cc1)NC1(C(=O)O)CC1 +O=S(=O)(Nc1ccc(F)c(Nc2ncccc2-c2ncnc3[nH]cnc23)c1F)c1ccccc1 +CCC(NC(=O)C(CC(C)C)NC(=O)OCc1ccccc1)C(=O)C(=O)NCCc1c[nH]c2ccccc12 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1ccccc1c2-c1ccc2cc[nH]c2c1 +CC(NC(=O)c1ccnnc1)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +Cc1ocnc1-c1ccc(OCCNCC(O)c2cccnc2)cc1 +CC(O)c1ccc(N2CCN(c3cc(-c4ccccn4)nc4ccccc34)CC2)cc1 +CCCCc1nc(Cl)c(CC(=O)O)n1Cc1ccc(NC(=O)C(Cc2ccccc2)n2cccc2)cc1 +Cc1ccccc1NC(=O)NCc1ccc(-c2n[nH]c3c2Cc2cc(CN4CCN(C)CC4)ccc2-3)s1 +COc1cccc(C(Oc2ccc3c(cnn3-c3ccc(F)cc3)c2)C(C)NS(=O)(=O)C2CC2)c1 +Cn1ncc(NC(=O)c2nc(-c3ccncc3F)sc2N)c1N1CCC(N)CC(F)(F)C1 +COc1cc(C(=O)NC2CCN(C)CC2)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C(C)C)CC2C +O=C(c1ccc(Oc2nccnc2N2CCCCC2)cc1)c1nc2ccccc2[nH]1 +c1cc(-c2ccc(CCN3CCCCC3)cc2)ccc1CCN1CCCCC1 +COc1cc2c(Nc3c(Cl)ccc4c3OCO4)ncnc2cc1OCC1CCN(C)CC1 +CC(c1ccccc1)N(C)c1ccnc(-n2cnc3ccncc32)n1 +CCC(C)C(CN(CC(=O)NC(CCSC)C(=O)O)Cc1cccc2ccccc12)NC(=O)Cc1cncn1Cc1ccccc1 +O=C(NO)c1cnc(N2CC3C(C2)C3NCC2CCCCC2)nc1 +Cc1nc2ccccc2n1C1CC2CCC(C1)N2CCC(CNS(=O)(=O)c1cccc(C(N)=O)c1)c1ccccc1 +NC1CN(c2ccc(-n3ccc(OCc4ccccc4)cc3=O)cn2)CC1c1cc(F)ccc1F +COc1ccccc1Oc1ccc(-c2cn(C3CCCC3)c3ncnc(N)c23)cc1 +O=C(Nc1ccc2[nH]ncc2c1)c1cc(N(CC2CC2)C2CCCCC2)ncn1 +COc1cnc(C(=O)Nc2ccc3c(c2)C2(CCOC(N)=N2)c2cc(-c4ccnc(F)c4)cc(F)c2O3)cn1 +O=C(NO)C1CN(c2ccc(C#CC#CC3CC3)c(F)c2)C(=O)O1 +CNC(=O)c1ccc(Nc2nccc(-c3cnc(COC)n3C(C)C)n2)cc1 +Cc1nc(N)ccc1CNC(=O)Cn1c(C)cnc(NC(C)(C)Cc2ccccc2)c1=O +CC1COC2=C1C(=O)C(=O)c1c2ccc2c1CCCC2(C)C 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+CC(=O)NC(C)c1ccc(CN2CCc3c(ccc(OCC4(C(F)(F)F)CC4)c3Cl)C2)cc1 +C=CC(=O)Nc1cccc(-c2c[nH]c3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn23)c1 +NC(=O)c1nn(-c2cccc(F)c2)c2c1ccc1[nH]ncc12 +CN(C)CC1CC2c3cc(F)ccc3Cc3ccc(F)cc3N2O1 +N#Cc1ccc(Cn2cncc2CNc2scc(-c3ccc(Cl)cc3)c2C#N)cc1 +C=CCC1Oc2cccc(C(=O)OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +CC(C)CCS(=O)(=O)C1CC2CN(c3ccc(OC(F)(F)F)cc3)C(=O)N2C1 +O=C(CCC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)N1CCC2(CCCC2)CC1)NC(Cc1ccc(Cl)cc1)C(=O)O +COc1ccccc1N1CCN(CCCCNC(=O)C=Cc2ccc(Cl)cc2)CC1 +c1ccc(COc2ccc(-c3cnc4c(-c5nnn[nH]5)cnn4c3C3CCCCC3)cc2)cc1 +Nc1nc(OCCc2ccccc2Cl)nc2c1ncn2C1OC(CO)C(O)C1O +O=P(O)(O)OC1COC(Cc2ccccc2)C1OC1OC(CO)C(OP(=O)(O)O)C(OP(=O)(O)O)C1O +Cc1ccc2cccc(OCc3c(Cl)ccc(N(C)C(=O)CNC(=O)C=Cc4ccc(N5CCCC5=O)cc4)c3Cl)c2n1 +CCN1CCC(c2ccccc2)=C(C(=O)OCCCc2ccc(OC)cc2)C1 +Cn1ccnc1-c1ccc2c(c1)N(c1nc3c(s1)C(=O)NC(C)(C)C3)CCO2 +O=C(c1ccc(F)cc1OCC(O)CN1CCC2(CC1)Cc1cc(Cl)ccc1O2)N1CCC(O)C1 +COc1cc(Nc2c(C#N)cnc3cc(-c4csc(CN5CCOCC5)c4)ccc23)c(Cl)cc1Cl +COc1cc(N2CCN(C(C)=O)CC2)ccc1Nc1ncc(F)c(Nc2ccc(N3CCN(C(C)=O)CC3)cc2OC)n1 +O=C(O)CC(=O)Nc1ccc(-c2cnc(N3CCOCC3)c3nc(C=Cc4ccc5ccccc5n4)cn23)cc1 +Cc1cc(C)c2c(n1)N=C(c1ccc(-n3c(C)nc4cnccc43)cc1)CC(=O)N2C +COc1ccc(C(=O)Nc2n[nH]c3c2CN(C(=O)N2CCN(CC4CCOCC4)CC2C)C3(C)C)nc1 +O=c1cc(C=Cc2cccc(F)c2)c2cc(C(c3ccc(Cl)cc3)c3nccs3)ccc2[nH]1 +Cc1cc(C)cc(OCC(=O)NNC(=S)NC(=O)C2CC2)c1 +Cc1cc(COc2ccc(C(=O)NC3CC(O)CC3C(=O)NO)cc2)c2ccccc2n1 +CCCOc1ccc2c(-c3ccc4c(c3)OCO4)c(C(=O)O)n(Cc3ccc4c(c3)OCO4)c2c1 +COc1ccc(-c2cc(NCc3cncn3Cc3ccc(-c4ccccc4)cc3)ccc2-c2nc3ccccc3s2)cc1 +COc1cc(-n2cnc3sc(-c4ccccc4)cc3c2=O)ccc1OCCN1CCCC1 +CC1COCCN1c1nc(N2CCOCC2C)c2ccc(-c3ccc(CNc4cc[nH]n4)o3)nc2n1 +COc1cc(N)c(Cl)cc1C(=O)NCC1CCNC(Cc2c[nH]c3ccccc23)C1 +Cn1c(=NNC(=O)CC2CCCC2)sc2cc(OC(F)(F)F)ccc21 +CCN(CC)CCNC(=O)c1cccc(S(=O)(=O)Nc2nnc(S(N)(=O)=O)s2)c1 +CCOC(=O)C1=C(CN2CCOCC2C(=O)O)NC(c2nccs2)=NC1c1cccc(F)c1Cl +Cc1ccc(-c2cnc(NC(=O)c3ccccc3)s2)cc1 +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NCC(c1cc(Cl)cc(Cl)c1Cl)N1CCC(N2CCCCC2)CC1 +Fc1cccc(-c2[nH]c(-c3ccccc3)nc2-c2ccncc2)c1 +Cn1c2cc(S(=O)(=O)CCCN3CCCC3)c(O)cc2c2c3c(c(-c4ccccc4Cl)cc21)C(=O)NC3=O +COCCCc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)ncc12 +COCC(O)C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +Cc1cc(=O)oc2c1ccc1oc(=N)c(C(=O)NCc3ccccc3Br)cc12 +CC12CCC(O)CC1=CCC1C2CCC2(C)C(c3ccno3)CCC12 +C=CC(=O)Nc1ccccc1C1CCNc2c(C(N)=O)c(-c3ccc(OCc4ccccc4)cc3)nn21 +CNC(C)C(=O)NC1C(=O)N(Cc2c(C)ccc3ccccc23)c2ccc(C#N)cc2N(C(C)=O)C1C +O=C(NCCn1cccc1)c1ccc(NC(=O)N2Cc3cccnc3C2)cc1 +NC(=O)c1cccc2[nH]n(C3CCN(C4CCC4)CC3)c(=O)c12 +Oc1ccc(-c2c(-c3ccccc3)[nH]c3ccccc23)cc1 +CNC(=O)c1cncc(-c2c[nH]c3ccc(-c4nnc(NC(C)C)o4)cc23)c1 +O=C(NS(=O)(=O)c1ccc(Br)cc1)c1ccc(Cl)cc1Cl +COC(=O)C(Cc1cccc(C(=N)N)c1)C(NC(=O)c1ccc(-c2cccc(CN)c2)cc1)C(C)C +NC1CCN(Cc2ccn3ncnc(Nc4ccccc4)c23)CC1 +N#Cc1ccc(S(=O)(=O)N2CC(O)(COc3ccc(C#N)c(Cl)c3)C2)c(Cl)c1 +O=S(=O)(c1ccc(F)cc1)N(CCCN1CCN(c2ccccc2)CC1)CC1CC1 +CNC(=O)C1OC(n2cnc3c(NCc4cccc(I)c4)nc(NC)nc32)C(O)C1O +CC(C)c1ccccc1OCCN1CC(NS(=O)(=O)c2ccc(F)cc2)C1 +CC1CN(C(=O)C2(C#N)CCC2)CC1Nc1c(C(N)=O)cnn2cc(-c3cnn(C)c3)nc12 +Cc1cc(Oc2cccnc2)c(S(C)(=O)=O)cc1C(=O)N=C(N)N +COc1cc(CN(CC2CC2)C(CC(=O)O)c2ccc(Cl)c(Cl)c2)ccc1SCCN1C(=O)CCC1=O +COc1ccc(-c2cccc(C(F)(F)F)c2)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C)N(CC(=O)NCC1CCN(c2ccc(C(F)(F)F)cc2)C1)S(=O)(=O)c1ccc(F)cc1 +O=C(NC1CCCCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1 +CCN(c1nc(C)cc(-c2cccc3ccccc23)n1)c1ccc(C(C)C)cc1Br +CC(C)(C)OC(=O)NCCCCCNC(=O)c1cc(-c2ccncc2)n2ncnc(N)c12 +CN(CC(C)(CCN1CCC2C(CCC(=O)N2Cc2ccccc2)C1)c1ccccc1)S(=O)(=O)c1ccccc1 +O=C(Nc1ccc(I)cc1)C1Cc2ccccc2CN1C(=O)c1cccc(Oc2ccccc2)c1 +Cc1cc(C(=O)N2c3cccc(O)c3NC3=C(C(=O)CC(C)(C)C3)C2c2ccc(OCc3ccccc3)cc2F)nn1C +Cc1nc(C)c(-c2ccc(C34CCC(CC(=O)O)(CC3)CC4)cc2)nc1C(N)=O +COc1ccc(C(C)(NCC(O)c2ccc(O)c(NS(C)(=O)=O)c2)C(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 +COc1cccc2c1CCCC2CCCN1CCN(CCCC2CCCc3c(OC)cccc32)CC1 +O=C(c1ccccc1)c1sc(NCc2ccc(F)c(F)c2)nc1-c1ccco1 +O=C(O)Cc1cc(CC(=O)O)cc(-c2ccc(C#CCO)s2)c1 +N#Cc1ccc(-c2ccc3c(c2)SC(=N)N2CCCN=C32)cc1 +COc1cc(N)c(Cl)cc1C(=O)OCCN1CCC(CCNS(=O)(=O)c2cccc3c(N(C)C)cccc23)CC1 +CCCNc1ncc(-c2cc(-c3c(Cl)cc(OC4CCCC4)cc3Cl)nc(-c3cnccn3)n2)s1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)OCC(O)=C(C#N)c1nc2ccccc2[nH]1 +Fc1cc(-c2ccncc2)cc(-n2nnc(-c3ccccn3)n2)c1 +COc1ccc2c(c1)CC(C(=O)Nc1ccc(-c3cn[nH]c3)c(OC)c1)CO2 +Cn1c(=N)n(CC(=O)c2ccc(Cl)cc2)c2cccc(Cl)c21 +N#CC1CCN(c2nccnc2OC2CC(Nc3ccc4ccccc4n3)C2)CC1 +CC1Cc2c(Br)cccc2N1C(=O)Cc1nc(N2CCOCC2)cc(=O)n1C +CN(Cc1ccccc1)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +COc1ccc2[nH]c(C(=O)O)c(CCN3C(=O)c4ccc(C(=O)O)cc4C3=O)c2c1 +CCc1c(NC(=O)NC(C)c2ccccc2)ncc2c(-c3ccnc(C)c3)n[nH]c12 +CCN(C(=O)Oc1ccc(F)cc1)C1CN(C(=O)C2CCN(c3ccc(F)cn3)CC2)CC1c1ccc(Cl)c(F)c1 +Cc1cccc(Nc2ccnc(Nc3ccc(N4CCN(C)CC4)cc3)n2)c1 +Cc1nc2c(N)ncnc2n1C1OC(CN(C)CCCCON)C(O)C1O +CCOC(=O)Oc1c(-c2ccc(Cc3ccc(OC(F)(F)F)cc3)cc2)c(C)nc2ccccc12 +Cc1c(C)c2ccc(OCc3ccc(F)c(F)c3)cc2oc1=O +COc1nc(N)nc2c1ncn2C1OC(CO)C(O)C1C#N +CC12CCC(O)CC1CCC1C2CCC2(C)C(C=CC=NOCCN)CCC12O +COc1ccc(CCN(CCCc2cccc(Br)c2)CCc2ccc3c(c2)OCO3)cc1OC +CC(=O)NC(C)C#Cc1cnc(Oc2ccc(OCC3CC3)cc2)s1 +Cc1ccc(CCCCNC(=O)n2c(=O)oc3ccccc32)cc1 +COc1ccc(Cn2c(N3CCC(N(C)C)C3)nc3ccccc32)cc1 +CC(=O)NC(CSC(=O)Nc1ccc(F)cc1)C(=O)O +Nc1ncc(S(=O)(=O)NCCOc2ccc3c(c2)C(C2(c4ccc(Cl)cc4)CCC2)NCC3)cn1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1ccccc1O +COc1ccc(CN2CCC(NC(=O)CNC(=O)c3cc(C(F)(F)F)ccc3N)C2)cc1 +CCN1C2CCC1CC(OC1c3ccccc3CCc3ccccc31)C2 +Cn1cc(-c2cccc(-n3ncc4cc(C(C)(C)C)ccc4c3=O)c2CO)cc1C(N)=O +c1cc(OCCCCCOc2cccc(C3=NCCN3)n2)nc(C2=NCCN2)c1 +COc1ccc(C(=O)NC(CC(=O)O)c2ccccc2C)nc1-c1ccccc1 +Cc1n[nH]c(CN2C(=O)C(NC(=O)c3cc4cc(Cl)ccc4[nH]3)Cc3ccccc32)n1 +CC(C)(C)c1nc(N2CCN(CCCSc3nccc(O)n3)CC2)cc(C(F)(F)F)n1 +C=CCC(CC=C)(COc1cccc(CN(CC)CC=CC#CC(C)(C)C)c1)OCc1ccsc1 +Cc1ccc(Cn2c(=O)[nH]c3c(N)nc(OCC4CCOC4)cc32)cn1 +O=c1c(CNc2nc3ccccc3s2)cn(-c2ccccc2)c2cc(Cl)ccc12 +COc1ccc(Nc2ncc(CN3CC[S+]([O-])CC3)cc2-c2nc(C)nc(N)n2)cn1 +CCCCNC(=O)c1ccc(Oc2ccc(CC(=O)O)cc2F)c(NS(=O)(=O)c2ccc(Cl)cc2Cl)c1 +CN1C(=O)Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3F)cc21 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+CN1C(=O)CCC2=C1C1Oc3c(O)ccc4c3C13CCN(C)C(C4)C3(O)C2 +COc1ccc2c(OCc3nnc4c(F)cc(-c5cnc(C)s5)cn34)ccnc2c1 +COc1ccccc1C(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC4CC4)cc3)C2)cc1 +Cn1cc(-c2ccc3nnc(Sc4ccc5ncc(N6CCCNCC6)cc5c4)n3c2)cn1 +CCc1c(CC2CCCCC2)n(COCc2ccccc2)c(=O)[nH]c1=O +CS(=O)(=O)Nc1ccc(OCC(O)CNCCc2ccccc2Cl)cc1 +COc1ccnc2c1nc(CCn1c(=O)n(C)c3c(C)ccnc31)n2-c1ccccc1 +Cc1nc(C)n(-c2cc(C3CC3c3nc4ccccc4n3C)nc(NC(C)C)n2)n1 +CCC(=O)N(c1ccccc1)C1(C(=O)OC)CCN(CCc2ccc(N=[N+]=[N-])cc2)CC1 +CSc1nc(-c2ccccc2)nn1C(=O)c1ccc(C)cc1 +COC(=O)c1c(NC(=O)CSc2ccccc2N)cnn1CCc1ccccc1 +N#CC(Cc1cccc(OCC(=O)O)c1)c1nc(-c2ccccc2)c(-c2ccccc2)o1 +Cc1[nH]nc2c1C(c1cc(N3CCOCC3)cc(C(F)(F)F)c1)(C(C)C)C(C#N)=C(N)O2 +Cc1ncn(C)c1CNc1ccc2ncc(C#N)c(Nc3ccc(F)c(Cl)c3)c2c1 +Cc1nc(NC(=O)N2CCCC2C(N)=O)sc1-c1ccc(S(C)(=O)=O)cc1 +CCCC1CC(=O)C2=C(C1)NC(C)=C(C(=O)OCC(C)C)C2c1ccc(C(C)(C)C)cc1 +NS(=O)(=O)Oc1ccc(-c2cccc(Cn3cncn3)c2)cc1 +O=C(Nc1ccc(-c2nnc3n2-c2cccnc2Nc2ccccc2-3)cc1)c1ccc2c(c1)OCO2 +Cc1sc2ncnc(Nc3c[nH]nc3C(=O)Nc3ccc(CN4CCOCC4)cc3)c2c1C +O=C(Nc1ccc(OC(F)(F)F)cc1)N1CC2CCN(c3ccc(OC(F)(F)F)cc3)C(=O)C2C1 +CC1C2Cc3ccc(O)cc3C1(C)CCN2Cc1cccc(I)c1 +Nc1c(C(=O)NCC(O)(CN(CCO)C(=O)c2c(F)cccc2F)C(F)(F)F)cnn1-c1ccc(F)cc1 +COc1nc(NS(=O)(=O)NCc2ccccc2)c(Oc2ccccc2OC)c(OCCOc2ncc(Br)cn2)n1 +N#Cc1ccccc1-c1ccc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)cc1 +Brc1cnc2nc(-c3ccc(CN4CC(c5n[nH]c(-c6ccccn6)n5)C4)cc3)c(-c3ccccc3)cn12 +COc1ccccc1N1CCN(CCCN2C(=O)CC(=C3c4ccccc4-c4ccccc43)C2=O)CC1 +CC(C)C(NC(=O)c1cc(C(=O)N2CCCC2C)c2n1CCOC2)c1ccc(F)cc1 +C=C(Br)C(=O)Nc1ccc2c(c1)cc(C(=O)NCCCCCCNc1nsc3nc4ccccc4n13)n2C +NS(=O)(=O)c1ccc(C=C2C(=O)Nc3ccc(F)cc32)cc1 +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccccc3C)cc12 +COc1ccc(-c2cc(-c3ccc(C)cc3O)[nH]n2)cc1 +CS(=O)(=O)c1ccc(-c2cccn3nc(Nc4cccc(N5CCC(N6CCOCC6)CC5)c4)nc23)cc1 +CN1CC2CC1CN2CCOC(c1ccccc1)c1ccccc1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3nc(C(=O)N4CCN(C)CC4)ccc3OC)NC(=O)NC1=O)C2 +CCCc1cc(Nc2nc(NCc3cc(C)no3)ncc2Br)n[nH]1 +O=C1CCC2(Cc3ccc(Cl)cc3)Cc3cc(O)ccc3C2=C1c1ccc(OCCN2CCCCC2)cc1 +COCCNc1nc(C)c(-c2nc3c(C)nccc3s2)c(NC2CC(C(C)(C)O)C(O)C2O)n1 +OC1(c2ccc(-c3ccccn3)cc2)CN2CCC1CC2 +CC1(C)C(=N)NC2(c3cc(NC(=O)c4cnsn4)ccc3F)COCC2S1(=O)=O +CC(C)CCOC1CCN(Cc2ccc(-n3nc(C(=O)N4CCOCC4)c4c3-c3ccccc3S(=O)(=O)C4)cc2)C1 +Cc1cc(N=Nc2ccc(S(=O)(=O)Nc3ccc(Cl)cn3)cc2)cc(C)c1O +COc1ccc(-c2cc(NCC(C)O)c3ccccc3n2)cc1C +Cc1ccccc1Cc1nnc(N2CCN(c3ccc(C(F)(F)F)cn3)CC2)c2c1CCC2 +CC(=Cc1ccc(C(=O)O)cc1)c1ccc2c(c1)C(C)(C)CS2 +CC(C)(C)OC(=O)N1CCCN(CC(=O)NC2C3CC4CC(C3)CC2C4)S1(=O)=O +COc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2csnn2)cc1 +O=C(NCC1(O)CCC1)c1cn(Cc2ccc(-n3cccn3)cc2)c2cccnc12 +CN(C)C(=O)c1cc2cc(Nc3nccc(-c4cc(OC5CCC(O)C5)ccn4)n3)ccc2[nH]1 +CS(=O)(=O)CC(=O)N(CCc1ccccc1)CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2 +COc1cccc(OC)c1OCCNC1COCC(c2ccccc2)(c2ccccc2)O1 +CC(=O)Nc1nc2c(Oc3cc(-c4ccc(C(F)(F)F)cc4NC(=O)C4CCC(C)(C)N4)ncn3)cccc2s1 +Cc1cccc(C)c1CNc1ncnc2c(C)c(C)[nH]c12 +CC1CCC(C(=O)N(c2ccc(Oc3ncccc3C(F)(F)F)cc2C(=O)O)C(C)C)CC1 +Clc1ccc(-[n+]2nc(-c3ccc(-c4ccccc4)cc3)nn2-c2ccccc2)cc1 +COc1cccc(-n2c(=O)n(CC(=O)Nc3ccc4c(c3)CC3(C4)C(=O)NC(=O)N3C)c3ccccc32)n1 +CC1CCC(N(NC(=O)c2ccc(CN3CCN(C)CC3)cc2)c2nc(C#N)ncc2Br)C1 +CC(C)n1nc(-c2cnc(N)c(C#N)c2)cc1C1CCN(C2COC2)CC1 +c1ccc(C2(CCc3nc(-c4ccccn4)no3)CCCCC2)cc1 +CC(C)=CCCC1(C)CCCC2(C)C(Cc3cc(C(=O)O)ccc3O)C(C)=CCC12 +COC(=O)C(CCSC)N(C(=O)c1ccccc1)C1CCN(Cc2cncn2Cc2ccccc2)CC1 +O=C(O)c1cc(F)cc(-c2cccc(COc3ccc4c(c3)CN(C3CCCC3)C4=O)c2)c1 +Cc1ccc(C=CC(=O)N2CCN(c3ccc(C(=O)Nc4ccccc4N)cc3)CC2)cc1 +O=C(Nc1cccc(-c2ccccc2)c1)C1CC(=O)N(C2CC3CCC2C3)C1 +Cc1cc(C)c(Nc2nc3ccccc3n2-c2cc(N)ncn2)c(C)c1 +COc1nn2cc(-c3cc4ccc([N+](=O)[O-])cc4o3)nc2s1 +CC(=Cc1csc(C)n1)C1CC2OC2CCCC(C)C(O)C(C)C(=O)C(C)(C)C=CC(=O)O1 +COc1cccc2c1OCC(C(=O)N1CCCC1c1ncc(-c3cccnc3)[nH]1)=C2 +O=c1oc(-c2cccnc2Oc2ccccc2)nc2cccc(Cl)c12 +Cc1nocc1-c1ccc2[nH]nc(-c3cc(N4CCOCC4)ncn3)c2c1 +Clc1ccc(Cn2c(C=NNc3nc(N4CCOCC4)c4sccc4n3)nc3ccccc32)cc1 +COCc1cnc(N2CCC(C3CC3COCc3ccc(S(C)(=O)=O)c(F)c3)CC2)nc1 +Cc1ccc(NC(=O)c2cccc(N3CCOCC3)c2)cc1NC(=O)c1ccc(OCc2ccccn2)cc1 +Cn1ccc2cc(-c3ccc4oc(Nc5ccc(F)cc5)nc4c3)ccc21 +O=C(NCCN1CCC(Cc2ccccc2)CC1)C(c1ccccc1)c1ccccc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)N1CCOC2(CCN(C(=O)c3cc(Cl)ccn3)CC2)C1 +CCC(Nc1n[s+]([O-])nc1Nc1cccc(C(=O)N(C)C)c1O)c1cc(C(C)C)co1 +Cc1cnc(Nc2ccc(CN3CCN(C)CC3)cc2)nc1-c1ccc(F)c(Cl)c1 +O=C(Oc1cccc2cccnc12)c1cccc(S(=O)(=O)N2CCCCCC2)c1 +COCC(NC(=O)Nc1cc2[nH]nc(OC3CCC(C#N)CC3)c2cn1)c1ccccc1 +CN1C2CCC1C(C(=O)N1CCCCC1)C(c1ccc(Cl)cc1)C2 +Cc1n[nH]cc1-c1nncc2nc(Nc3ccc(F)cc3F)ccc12 +CC1CN(c2ccc(F)cc2C(F)(F)F)CCN1S(=O)(=O)c1ccc(N2CCOCC2)cc1Cl +Cc1nc(C(C)(CC2CC2)NC(=O)c2cc(OC(C)C(F)(F)F)c(C3CC3)cn2)no1 +CC(NC(=O)OC(C)(C)C)C(=O)Nc1nc2ccc(Cl)cc2c2nc(-c3ccco3)nn12 +CCN1C(=O)c2nc(Br)n(Cc3ccc(OC)cc3)c2N2CC(Cc3ccccc3)N=C12 +CC1(C(=O)Nc2cnn3ccc(N4CCCC4c4cc(F)ccc4Cl)nc23)CCNCC1 +CC(C)N1CCCCC1c1nc2c(C(N)=O)cccc2[nH]1 +Cc1cccc(C)c1Nc1ncc(-c2ccc(N(C)C)cc2)n2cncc12 +CCOC(=O)c1[nH]c2ccc(Br)cc2c1Cc1cc(O)c(OC)c(OC)c1 +O=S1(=O)CCOc2ccc(Cc3cc(C4OC(CO)C(O)C(O)C4O)ccc3Cl)cc21 +CNCCCCNCCCCNCc1c2ccccc2c(CNCCCCNCCCCNC)c2ccccc12 +COc1cccc(C2OC(CC(=O)N(C)CC(=O)O)C(=O)N(CC(C)(C)CO)c3ccc(Cl)cc32)c1OC +COc1cc(C=C2CCCC(=Cc3ccccc3[N+](=O)[O-])C2=O)cc(OC)c1OC +CC(OCc1cc(Cl)cc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1)C(F)(F)F +N#Cc1nn(-c2cccc(C(F)(F)F)c2)c(=O)n(CCN2CCCCC2)c1=O +CC1(C)OC(=O)Nc2ccc(-c3cccc(C#N)c3)cc21 +Cc1ccc(S(=O)(=O)N(C)c2ccccc2N(C)S(=O)(=O)c2ccc(C)cc2)cc1 +CCCC(NC(=O)N1CC(=NOCC(F)(F)F)NCC(Cc2cc(Cl)ccc2OC)C1=O)c1ccc(C(=O)O)c(N)c1 +O=S(=O)(Nc1ccc2[nH]cc(CC3CCCN3)c2c1)c1ccc(I)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(OCC4CC4)c(F)c3)C2)cc1 +CCOc1cc(CN2CC3(CC(c4cccc(C(=O)O)c4)=NO3)C2)cc(OCC)c1-c1ccc(F)cc1 +COc1cc(Nc2nc3n(n2)CCC(C)(O)CC3c2ccc(F)cc2)ccc1-n1cnc(Cl)c1 +COc1cc(N2CCN(C3CCN(c4cccc5c(OC)cc(C(F)(F)F)nc45)CC3)CC2)c2ncccc2c1 +O=C(Nc1nc2ccc(C3(O)c4ccccc4C(=O)N3c3cccc(Cl)c3F)cc2[nH]1)OCC1CCCN2CCCCC12 +Cc1nc2cnccc2n1Cc1ccc(S(=O)(=O)N(C)C(CC(C)C)C(=O)NCc2cccc(N)c2)cc1 +O=c1[nH]c(Cc2ccccc2)nc2sc3c(c12)CCCCC3 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+Cc1ccc(Oc2ccc(C(=O)NCCN3CCCC3)cc2NC(=O)Nc2ccc(-c3ccccc3)cc2)cc1C +CC1(c2cccc3ccccc23)NC(=O)N(CCCn2ccnc2)C1=O +N#Cc1c[nH]c2nc(N)nc(-c3ccc(CO)cc3)c12 +COc1cc2c(cc1OS(N)(=O)=O)CCC1C2CCC2(C)C(=O)CCC12 +COc1cc(-c2ccccn2)c(F)cc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +Cc1cc(C)nc(OCCCn2c3c(c4cc(C#N)ccc42)CCCC3)n1 +CCNC(=O)Nc1cc2c(-c3ccnc(C)c3)ccc(COC(=O)N3CCN(C)CC3)c2cn1 +O=c1cc(-c2ccccc2)oc2ccc3c(c12)OCC=C3 +CS(=O)(=O)c1ccc(-c2[nH]c3ncnc(NCC4CCCO4)c3c2-c2ccccc2)cc1 +CC(C)C(c1ccc(-c2ccccc2)nc1)n1ccnc1 +O=C(O)Cc1sc(Nc2cccc3ccccc23)nc1-c1ccc(Cl)cc1 +CNC(=O)C1OC(n2cnc3c(NC)nc(C#Cc4ccccn4)nc32)C(O)C1O +CC(C)C(CO)NCc1nc(N2CCc3ccc(C(F)(F)F)cc3C2)ccc1F +CCCN1C(=O)C(NC(=O)Cc2ccc(C(F)(F)F)cc2C(F)(F)F)N=C(C2CC2)c2ccccc21 +COc1ccc(CNCC2(N3CCN(C(=O)C4CN(C(C)C)CC4c4ccc(Cl)cc4)CC3)CCCCC2)cc1F +CC(C)(C)c1cc(NC(=O)Nc2cccc3ccccc23)n(-c2cccc(C(=O)NCCOCCO)c2)n1 +CC1CCCCC1Oc1nc(N)c2c(=O)ccn(C3CCCC3O)c2n1 +COc1cc(F)c(-c2cc(Cl)cc(C(CC(=O)O)c3ncc(C)s3)c2)c(F)c1 +CNC(=O)C1CCN(S(=O)(=O)CC2CCC(N(C)c3ncnc4[nH]ccc34)CC2)CC1 +CN1C(=N)NC(=O)C1=Cc1c[nH]c2cccc(Br)c12 +CN1C(=O)Nc2cccc(Cl)c2C12NC(=O)NC2=O +N#Cc1cc(-c2ccnc(Nc3ccc(NC(=O)CN4CCOCC4)nc3)n2)cnc1N1CCC(F)C1 +CCn1c(=Cc2sc3ccccc3[n+]2C)sc(=CC=c2nc3c(o2)=CC=CN3C)c1=O +NC(=S)NN=C(c1cccc(Br)c1)c1cccc(F)c1F +COC1CCN(c2ccc(C(=O)NCc3cn(-c4ccccc4)c4cc(Cl)ccc4c3=O)cn2)CC1 +O=C(C=Cc1cccnc1)Nc1ccc(S(=O)(=O)c2cc(Cl)cc(C(F)(F)F)c2)cc1 +COc1cccc(CN(CCN2CCCC2)C(=O)c2cc3ccc(-c4cn[nH]c4)nc3n2C)c1 +OC1CCCc2nc3cc(Cl)ccc3c(NCc3ccc(F)cc3)c21 +COc1cc(OCc2nnc(-c3ccccc3)s2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +OC(CN1CCC(c2nnn3cnc4[nH]ccc4c23)CC1)c1ccc(C(F)(F)F)cc1 +NC(=O)c1[nH]c2ccc(Cl)cc2c1S(=O)(=O)c1cc(Cl)ccc1N +c1ccc(-c2nn3c(c2-c2ccnc4ccccc24)CCC3)nc1 +CCCOc1ccc(Oc2ccc(-c3ccc(C(C)NC(=O)CC)cc3)cn2)cc1 +Cc1cccc(C(=O)Nc2ccc3c(c2)CC(NS(=O)(=O)c2cccs2)C3)c1-c1ccc(C(F)(F)F)cc1 +Cc1ccc(C(CC(N)=O)NC(=O)CCCOc2c(CCCO)c(-c3cccnc3)nn2-c2ccc(Cl)c(Cl)c2)cc1 +NC(COCc1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(c1ccccc1)c1ccccc1 +COC(=O)C1C(CO)=Cc2cc3c(cc2C1c1cc(OC)c(OC)c(OC)c1)OCO3 +NS(=O)(=O)c1cccc(N=Nc2ccc(O)cc2)c1 +Nc1nc(Nc2ccc(N3CCOCC3)cc2)nn1-c1ccccn1 +CC1CCC(C(C)C)C(NC(=O)Oc2ccc(Cl)cc2)C1 +O=C(NO)c1ccc2c(c1)CC(NS(=O)(=O)c1cccnc1)CC2 +CCCCN1CCc2cc(Cl)c(O)cc2C(c2ccccc2)C1 +O=C(Nc1nc2cccc(-c3ccc(CN4CCCCC4)cc3)n2n1)C1CC1 +CCCCC(=O)NC(CCC(=O)N1CCC(CCCC2CCNCC2)CC1)C(=O)O +c1ccc2c(c1)CCN=C(NCc1ccc3c(c1)OCO3)N2 +CCOc1n[nH]c2cc(NC(=O)NC(c3ccccc3)C(C)(C)OC)ncc12 +COc1ccccc1-n1nc(OC2CCC(NC(=O)C(F)(F)F)CC2)cc1-c1ccc(Cl)cc1 +CC(C)c1nc(-c2cccc(NS(=O)(=O)c3c(F)cccc3F)c2)c(-c2ccnc(N)n2)s1 +O=C1NC(=O)C(c2cnc3ccncn23)=C1c1cn2c3c(cccc13)CN(C(=O)N1CCOCC1)CC2 +N#CC1CCCN1C(=O)CNCCC(=O)N1CCc2cc(F)ccc2C1 +COc1cccc(CNC(=O)c2cc3ccc(-c4ccncc4)nc3[nH]2)c1 +Cc1cc(-c2n[nH]c3cc(NC(=O)NCc4c[nH]nn4)ncc23)ccn1 +Nc1nn2cccnc2c1C(=O)Nc1cn(C2CCN(Cc3ccccc3)CC2)nc1-c1cc(Cl)ccc1OC(F)F +Cn1cc(-c2c(F)cncc2C=CC(=O)Nc2ccc(CN3CCOCC3)cc2)cn1 +Cc1ccc(C(=O)Nc2cccc(N3CCOCC3)c2)cc1-c1ccc2nc(N)[nH]c(=O)c2c1 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+O=C(CCCCN1CCCCCC1)Nc1ccc(-c2cccnc2)cc1 +O=C(CN(Cc1ccc([N+](=O)[O-])cc1)S(=O)(=O)c1cc(Cl)ccc1Cl)NO +COc1ccc(C)cc1S(=O)(=O)N1CCCc2ccc(C(=O)Nc3nc(CC(=O)O)cs3)cc21 +CC1(C)CC(=O)c2sc(N3CCOc4ccc(Br)cc43)nc2C1 +CNc1nnc(-c2ccc3[nH]cc(-c4cccc(OC(C)C)n4)c3c2)o1 +O=C(NC1CCCCN(CCc2ccc(F)cc2)C1)c1ccc2[nH]nc(-c3ccncc3)c2c1 +Cn1nnc(-c2ccc(Nc3nccc(-c4cc(C#N)cc(N5CCOCC5)c4)n3)cc2)n1 +Cc1ccc2cnc(N(Cc3ccc(OC(F)(F)F)cc3)S(=O)(=O)c3ccc(C(=O)O)cc3)c(C)c2c1 +Nc1ncnc2c1ncn2C1CC(OP(=O)(O)O)C2(COP(=O)(O)O)CC12 +CCNC(=O)Nc1ccc(-c2nn(CC)cc2-c2ccnc3[nH]c(-c4cccc(CN(C)C)c4)cc23)cc1 +Cc1ccc2c(c1C)N(S(=O)(=O)c1ccc(C(C)(C)C)cc1)Cc1ccc(C#N)nc1N2 +CC1CC(c2ccc3nc(-c4ccccc4)oc3c2)=NNC1=O +CCCCCCCCCCCCCCCNOC(=O)CC1COC(COC(=O)N(Cc2cccc[n+]2CC)C(C)=O)O1 +CNS(=O)(=O)NC(=O)c1cc(Cl)c(Oc2cnc(OCC(C)C)c(Cl)c2)cc1F +CC(C)(O)c1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(Br)cc2)sc2ccccc12 +O=C(Nc1c(Cl)c[n+]([O-])cc1Cl)C(=O)c1cc(Cc2ccc(O)cc2)n2ccccc12 +COc1ccc(-c2n[nH]c3c2C(C2CCCCC2)N(Cc2cc(C)on2)C3=O)cc1 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+Cc1[nH]c(C=C2C(=O)Nc3ccc(F)cc32)c(C)c1NC(=O)CCNC(C)(C)C +CCC(C)Oc1cc2c(cc1OC)CC(=O)N(c1ccc(N3CCCC3=O)cc1)C2c1ccc(Cl)cc1 +Cc1ccc(-c2cc(Br)ccc2OCc2c(F)cccc2C(F)(F)F)n1-c1cccc(C(=O)O)c1 +COc1cnc2c(Nc3ccc(F)c(C4(CF)CC(C(F)(F)F)OC(N)=N4)c3)nccc2n1 +CC1CN(c2ccccn2)CCN1C(=O)C12CC3CC(CC(C3)C1)C2 +Cc1nc(C=O)c2c(n1)N(Cc1ccc(-c3ccccc3-c3nn[nH]n3)cc1)C(=O)CC2 +Cn1cc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2(C)C +O=C(C=Cc1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C2)NS(=O)(=O)c1cccc(Cl)c1 +CN1CCN(CCCN2CCC3(N4CCN(C)CC4)CC(c4ccccc4)C2C(c2ccccc2)C3)CC1 +CC(C)(C)Sc1c(CC(C)(C)C(=O)O)n(Cc2ccc(Cl)cc2)c2ccc(OCC3CCC(=O)N3)cc12 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OC1CC2OCC(OC)C2O1 +O=C(CCCN1CCN(CCC2Cc3sccc3C2=O)CC1)c1ccc(F)cc1 +O=C(Cc1ccc(F)cc1)Nc1nc(-c2ccncc2)cs1 +CCOC(=O)C(=Cc1cc(=O)c(OC)co1)C(=O)OCC +CC(=O)Nc1cc(Cl)ccc1C=CC(=O)N1CC(C)N(Cc2ccc(F)cc2)CC1C +CCOC(=O)C(C)(C)Oc1ccc(NC(=O)c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2C)cc1 +COc1cc(NC(=O)c2ccc(C(C)(C)C)o2)ccc1-c1cnco1 +COc1nc(NCCc2ccc(F)cc2)nc(-c2ccc3ncccc3c2)n1 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+Cc1cc(CC(CC(=O)N2CCC(c3cc4ccccc4[nH]c3=O)CC2)c2ccccn2)cc2cn[nH]c12 +Cc1nn(-c2cccc(Nc3ccc4c(c3)c(C(=O)C(F)(F)F)cn4C)n2)cc1CN1CCC(O)C1 +O=c1ccc(-n2cnc3ccccc32)nn1CCCCN1CCN(c2ccccc2Cl)CC1 +COc1ccc(N(C)Cc2cnc3nc(N)nc(N)c3c2C)cc1 +O=C(COc1ccc(C(F)(F)F)cc1)NNC(=S)NCCCCC1CCCCC1 +CC(C)N(Cc1ccccc1)c1nc(O)nc(Nc2ccc3ncsc3c2)n1 +COc1ccc(F)cc1-c1ccnc2[nH]c(C3=CCC(N4CCCC4C(=O)O)CC3)cc12 +COc1ccc(C2=C(c3ccc(S(N)(=O)=O)cc3)CC3(CC3)C2)cc1F +COCCN1CCN(c2ccc(Cn3c(=O)[nH]c4c(N)nc(C(F)(F)F)cc43)cn2)CC1 +Cc1ccccc1OC(=O)N1c2ccccc2Sc2ccccc21 +Nc1cc2[nH]c(C(=O)NCc3ccc(S(=O)(=O)c4cc(F)cc(F)c4)cc3)cc2cn1 +COc1ccc(Nc2ccnc3ccc(-c4ccc(S(=O)(=O)N5CCOCC5)cc4)cc23)cc1C +COc1ccc2cc3[n+](cc2c1OCCCCOc1ccccc1)CCc1cc2c(cc1-3)OCO2 +COc1cccc2c1CCCC2OCCN1CCN(C2CCCCC2)CC1 +O=C(NC(Cc1ccc(F)c(Br)c1)C(=O)O)c1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccc2nsnc12 +CC(c1nc2ccccc2c(=O)n1C)N1CCN(C(=O)C(C)(C)C)CC1 +CC(=O)Nc1cccc(N2CCN(CCCCNS(=O)(=O)C(C)C)CC2)c1 +COc1ccc(CC(=O)Nc2nc3nn(C)c(SC)c3c3nc(-c4ccco4)nn23)cc1 +CC(C)c1ccc(CNC(=O)c2cn3cc(-c4ccc(C5CCC(CC(=O)O)CC5)cc4)ccc3n2)cc1 +CCOCC1CC2C(C)SC(N)=NC2(c2ccc(F)cc2F)CO1 +[C-]#[N+]c1cccc(C2CN3CCN(C(=O)C4CCc5nc(-n6cnnn6)ccc54)CC3CO2)c1C +c1cc(OCc2ccc(COc3cccc(C4=NCCN4)c3)cc2)cc(C2=NCCN2)c1 +Cc1c(Cc2ccccc2S(=O)(=O)c2ccccc2)c2c(n1CC(=O)O)CCNC2=O +CC(NC(=O)Nc1cc2[nH]nc(-c3ccc(F)cc3)c2cn1)c1ccc(F)c(Cl)c1 +O=C(CCCc1ccc(N(CCCl)CCCl)cc1)NN=CCN1C(=O)C=CC1=O +CCCOC(=O)C1=C(Nc2ccc3ccccc3c2)SCC1=O +Cc1ccc(C(=O)Nc2nc(-c3ccccn3)cc3ccccc23)cc1C +Cc1c(-c2ccc(Cc3ccc(OC(F)(F)F)cc3)cc2)[nH]c2cc(O)ccc2c1=O +CC1CNC(=O)c2[nH]c3ccc(C(=O)Nc4nc(C(=O)NCCO)cs4)cc3c21 +Cc1n[nH]c2ccc(-c3cc(NC(CO)c4ccccc4)cnc3-c3cccc(F)c3O)cc12 +CC(C)(NC(=O)c1ccc(C2CC2)c(OCC2CC2)n1)c1nc(N)no1 +COc1ccc(NC(=O)C=C2c3nc4ccccc4cc3C(=O)N2c2ccc(Cl)cc2)cc1 +O=C(Nc1c(Cl)cncc1Cl)c1ccc(CO)n2nc(C(F)(F)F)cc12 +COc1cc(-c2cc(=O)c3ccc(C)cc3o2)ccc1O +O=C(NCc1cccnc1)c1ccc(N2CCC3(CCc4ccccc4O3)CC2)nn1 +O=C(O)c1csc(C2CCC3C(CC(O)C3COc3ccccc3F)O2)n1 +Oc1cccc(-c2cc(N3CCOCC3)nc(NCc3ccncc3)n2)c1 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+CC1(COc2cc(F)c(C(=O)NS(=O)(=O)C3CC3)cc2C2CC2)CC=CCC1 +CCN(CC)CCNc1ccc(CO)c2sc3ccccc3c(=O)c12 +Cc1nc2c(nc1-c1cc3nc(N4CCCC4)cc(NC4CCC(C)(O)CC4)n3n1)CCCO2 +O=C(c1csc(Cc2n[nH]c(=O)c3ccccc23)c1)N1CCN(C(=O)c2ccccn2)CC1 +CC(=O)c1ccc(N2CCN(Cc3ccccc3)CC2)cc1 +CCOC1(C)CN(c2cc(-c3cnc(N)c(OC(F)F)c3)nc(N3CC4CC3C4)n2)C1 +Cc1cc(C)c(C(=O)C=Cc2ccc(O)c(O)c2)c(C)c1 +Cc1cc(C)c(NC(=O)c2ccc3nc(Nc4cc(C)nc(C)n4)sc3c2)c(C)c1 +Cc1noc(NS(=O)(=O)c2ccccc2-c2ccccc2N(C)C)c1C +Fc1ccc(SCCCN2CCN(c3ccc(Cl)cc3)CC2)cc1 +CCC(C)N1CCN(C(=O)C=Cc2ccc(Br)cc2)CC1 +CC(c1ccccc1)C(O)C=CC1C2CCC(O2)C1CC=CCCCC(=O)O +COc1ccc(-c2oc3ncnc(NCCCN4CCOCC4)c3c2-c2ccc(OC)cc2)cc1 +Oc1ccc2c(c1)C13CCN(CC4CC4)CC1(C2)Cc1c([nH]c2ccccc12)C3 +O=C(NCC(=O)N1CCCCC1)c1cc(Cc2n[nH]c(=O)c3c2NCCC3)ccc1F +CCc1c(C(=O)O)cccc1-c1cc(C)cc(Nc2nccc(C(F)(F)F)n2)c1 +O=C(CCCN1Cc2cc3c(Nc4cccc(Br)c4)ncnc3cc21)N1CCOCC1 +CC(C)(C)CCN1C(=O)C(C2=NS(=O)(=O)c3ccccc32)=C(O)C1C(C)(C)C +CC(CCn1ccc(C2=CCCCC2)cc1=O)(C(=O)NO)S(C)(=O)=O 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+COc1cc2[nH]c(-c3cccc(Oc4ccccc4)c3)c(C(=O)OCCO)c(=O)c2cc1F +CCCCCN(CCCCC)C(=O)Cc1cc(-c2ccccc2)no1 +CNc1nc(C2c3ccc(F)cc3CN2C(=O)C(O)C(O)C(=O)NC(C)c2ccc(-n3cccn3)cc2)cs1 +O=C1CC2(CCN(CCc3ccccn3)CC2)Oc2ccccc21 +COCC(=O)N1CCN(c2nc(C)c3cc(NC(=O)COc4ccc(Cl)cc4)ccc3n2)CC1 +CCC(O)(CC)c1ccc2cc(-c3n[nH]c4cc(-c5ccccc5)sc34)[nH]c2c1 +CC(c1ccc(C(C)(C)C)cc1)N1CCC2(CCC(O)CC2)OC1=O +Cc1ccc(C(=O)c2ccc(C(=O)c3ccc(C(=O)O)cc3)cc2)cc1 +Cn1c(=N)n(CC(=O)c2ccc(C(C)(C)C)cc2)c2ccccc21 +Cc1ccc(-c2nn(CCCCCCCN3CCN(c4cccc(C(F)(F)F)c4)CC3)c(=O)c3ccccc23)cc1 +CCC(O)Cn1c(C)c(C(=O)Nc2ccc(Oc3ccnc4cc(OC)ccc34)c(F)c2)c(=O)n1-c1ccccc1 +CC(=O)NC(C)c1ccc(CN2CCc3cc(OCCC(F)F)ccc3C2)cc1 +CC(C)(N)C(=O)NC(COCc1ccccc1)c1nnnn1CCOC(=O)NCCCn1ccnc1 +COc1cc(Br)c(S(=O)(=O)Cc2ccc(Cl)c(OC3CCN(C)C3)c2)cc1OC +CN(C)C(=O)c1ccc(N(C)C(=O)c2ccc(O)cc2O)cc1 +O=C(NCC(NS(=O)(=O)c1cccnc1)C(=O)O)c1ccc2c(c1)C(=O)N(CCC1CCNCC1)C2 +CS(=O)(=O)c1ccc(N2N=C(C(F)(F)F)CC2c2ccc3ccccc3c2)cc1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(-c2cccc(-c3c[nH]cn3)c2)cc1 +CN1C(=O)NCc2c(NC(=O)NC3CCOc4c(OC(F)(F)F)cccc43)cccc21 +Oc1nc(CCCN2CC=C(c3ccccc3)CC2)nc2cc(Cl)ccc12 +O=C(O)c1cccc(Oc2cccc(CCNCC(O)c3cccc(Cl)c3)c2)c1 +CN(C)Cc1cn2c(-c3ccncc3)c(-c3ccc(F)cc3)nc2s1 +Cc1ccc(OCC(=O)Nc2ccc(OCC(=O)O)c(F)c2)cc1 +CN(C)CCCON=C1c2ccccc2-c2nc3c(CN4CCC(N5CCCCC5)CC4)cccc3nc21 +CCCCOc1ccc(C(CC)NC(=O)Oc2ccccc2)cc1 +CCCc1ccc(CSCC(NC(=O)C(C)CS)C(=O)O)cc1 +Cc1cc(NCCCNc2ccnc3cc(Cl)ccc23)nc(NCCCO)n1 +CN1Cc2c(C3=CCN(S(C)(=O)=O)CC3)[nH]c3nccc(c23)-c2cccnc21 +CCOc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)CC1(c3ccc(F)cc3)CC1)CC2 +Cc1ccc2c(c1)C(OC1CC3CCC(C1)N3C)c1ccccc1CC2 +O=C1NN=C(c2ccc3nc(-c4ccc(OCCN5CCOCC5)cc4)oc3c2)C2CC12 +CC(c1cncc(-c2cnc3c(c2)CCCN3C(N)=O)c1)N1CCOCC1=O +COc1ccc(C)cc1-c1cc(OC)c(-n2c(=O)ccc3cc(S(=O)(=O)Nc4ccon4)ccc32)cc1F +Nc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)N3CC(F)(F)C3)cc2F)cn1 +COc1ccc(C2c3nc(CC(C)C)ccc3C(c3ccc4c(c3)OCO4)C2C(=O)O)cc1 +Cc1ccc(C(C)C)cc1N1CCc2nc(-c3c(C)ccc4[nH]nc(C)c34)nc(N3CCC3C)c2C1 +O=P(O)(O)OCCCC1OC(CO)C(OP(=O)(O)O)C(OP(=O)(O)O)C1O 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+CC(C)(C)n1ncc(OCc2ccc(OCCCF)cc2)c(Cl)c1=O +COC(=O)c1ccc(C(C)n2[nH]c(=O)c3[nH]c4cc(Cl)ccc4c(=O)c3c2=O)cc1 +N=C(N)c1ccc(-c2cc(-c3ccc(C(=N)N)cn3)no2)cc1 +O=C(O)c1ccc2c(C3CCCCC3)c(-c3ccccn3)[nH]c2c1 +COc1ccc(CN2c3ccc(OC(C)=O)cc3C(C)=CC2(C)C)cc1 +COc1cc(-c2ccc3ncc(C(=O)C4CC4)c(NC4CCC(CN(C)C)CC4)c3c2)cc(Cl)c1O +CC(C)N1CCc2nc(C(=O)Nc3cc(C(=O)O)ccc3CNC(=O)c3ccc(Cl)s3)sc2C1 +COc1ccc2c3c1OC1C4(OC)CCC5(CC4CSc4nncs4)C(C2)N(CC2CC2)CCC315 +COc1ccc(OC)c(-c2ccc(O)c(CNCC3(N4CCCCC4)CCCCC3)c2)c1 +Cc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(C(C)(C)C)c2)c1 +COc1ccc(OCC(O)CN2CCN(C(CNC(=O)c3ccccc3OC)c3ccccc3)CC2)cc1 +O=C(O)c1ccc(N2CC3(CCN(Cc4cc(OC(F)(F)F)ccc4-c4ccc(F)c(F)c4F)CC3)OC2=O)cc1 +Cn1c(=O)c2cn(Cc3cccc4ccccc34)cc2n(CC2CC2)c1=O +CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c(C=CC(=O)NS(=O)(=O)c3ccc(F)c(F)c3)cccc21 +O=C(CSC(=S)NN1CCSCC1)NCc1ccc2c(c1)OCO2 +CC1(C(=O)NC2C3CC4CC2CC(O)(C4)C3)CCCN1S(=O)(=O)c1ccc(-c2ccccc2)cc1 +O=C(Nc1cnc(-c2ccncc2)c(-c2ccco2)n1)C1CCC1 +O=C(NCc1ccc(Cl)cc1Cl)c1ccc(OCC(F)(F)F)nc1 +O=C(Cc1ccncc1)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +Cc1cccc2oc(-c3cccc(CC(O)C=CC4CCC(=O)N4CCSc4nc(C(=O)O)cs4)c3)nc12 +Cc1cc(OCc2ccc(F)cc2F)c(Br)c(=O)n1Cc1cccc(C(=O)N(C)C)c1 +CN(c1ncccc1CNc1c(C(F)(F)F)cnc2[nH]c(-c3ccc(Br)cc3)nc12)S(C)(=O)=O +COc1ccc(C(=O)Nc2ccc(F)c(C3(C)N=C(N)OCC3(F)F)c2)nc1 +O=S1(=O)c2cccc3cccc(c23)N1CCCCN1CC=C(c2ccccc2)CC1 +CC1=CC(=O)N(Nc2nc(-c3cccs3)nc3sc(C#N)c(C)c23)C1=O +CC(C)Oc1ccc(-c2cc3c(NC(P(=O)(O)O)P(=O)(O)O)ncnc3s2)cc1 +CCCCOP(=O)(CC(CCc1ccccc1)OP(=O)(OCCCC)OCCCC)OCCCC +Cc1n[nH]c(NCC2CCC(NC(=O)c3cc(C(F)(F)F)ccc3Cl)CC2)c1-c1ccccc1 +Nc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2cnc(C3(O)CCCc4cc(C(=O)O)ccc43)s2)c1 +Cc1nnc(CNc2cc(OCC3CC3c3ccc(Cl)cn3)nn(C)c2=O)s1 +COc1ccccc1-n1c(-c2cccc(O)c2)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 +FC(F)Oc1ccc(-c2ccc3c(c2)CN2CCC3(c3ccc(Cl)cc3)C2)nn1 +CCC(NC(=O)c1cc(C(=O)NCc2nccs2)n2c1COCC2)c1ccccc1 +COc1cc(C=Cc2cc(OC)c(OC)c(OC)c2)cc(NC(=O)c2cn(Cc3ccc(F)cc3)nn2)c1OC +O=C(NC1CCCOC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 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+CNC(=O)C12CC1C(n1cnc3c(NCc4cccc(Cl)c4)nc(C#CCCCC(=O)O)nc31)C(O)C2O +c1ccc2c(c1)N=C(N1CCN(CC3CCCO3)CC1)c1ccccc1S2 +O=C(CCS(=O)(=O)N1CCC(Oc2ccc(-n3ccnc3)cc2)CC1)NO +CCC(C1CC1)n1c(=O)c(C)nc2c(-c3ccc(C)cc3C)ccnc21 +COc1ccc(C2CN(CCc3ccc(OC)c(OC)c3)CC2CC(=O)Nc2cccc(Cl)c2)cc1 +CN1Cc2c(C3=CCN(C4CCC(C(=O)O)CC4)CC3)[nH]c3ncc(F)c(c23)-c2ccccc21 +Cc1cccc(-c2[nH]c(CNc3cc(C#N)ccc3CN3CCCC3)nc2-c2ccc3ncnn3c2)n1 +CC(CN1CCc2cc(F)ccc21)NC(=O)OC(CC1CCCCC1)C(=O)N1CCOCC1 +CC1CC2CSC(N)=NC2(c2nc(NC(=O)c3cnc(OC4CC4)cn3)cs2)CO1 +CCCCc1cn(CCCC)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)nc1 +CCn1c2ccccc2c2cc(CNc3cnc(-c4ccc(CC(N)C(=O)O)cc4)cn3)ccc21 +CCOC(=O)CCCOc1ccc(OCc2ccc3ccccc3n2)cc1C1(c2ccccc2)CC2CCC1C2 +CCCCOc1ccc(S(=O)(=O)N(CC(=O)NN=C2C(=O)Nc3ccccc32)c2ccc(Cl)cc2)cc1 +Cc1cncn1CCCNC(=S)Nc1ccc2c(c1)CCCC2=O +Cc1nc(NC(C)c2cc(F)cc(-c3cnc(Cl)c(N)c3)c2)cc(-c2ccc3occ(C)c3c2)n1 +O=C(O)CCCc1nc(CCCc2ccc3c(n2)NCCC3)no1 +CN(C)CC(C)(C)COc1ccc(NC(=O)Nc2cccnc2Oc2ccccc2C(C)(C)C)cc1 +ClC(Cl)(Cl)c1nc(Nc2ccc(Br)cc2Br)c2ccccc2n1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC3CN(c4nccc(-c5ccccc5)n4)CC3C2)c1 +CN(C)C(=O)c1coc(C(CCCC2CCCCC2)CC(=O)NO)n1 +CC(=NNS(=O)(=O)c1cc([N+](=O)[O-])ccc1C)c1c(C)nc2ccc(Br)cn12 +CC1(c2cc(NC(=O)c3ccc(Cl)cn3)ccc2F)CS(=O)(=O)C2(CCOCC2)C(=N)N1 +O=C1Nc2ccc(F)cc2C1=C1Nc2ccc(O)cc2C1=NO +Cc1cc(OCC2CCC(C(=O)O)C2)c(NC(=O)Nc2cnc(C#N)cn2)cc1Cl +CC(O)(COc1ccccc1F)C(=O)N1CCc2c(C#N)cccc21 +CCN(CC)c1ccc(N2CCN(Cc3ccc(F)cc3Cl)C(=O)C2=O)c(C)c1 +N#Cc1ccc2[nH]c3c(c2c1)CCc1c[nH]nc1-3 +CC(C)CN(c1cccc(C(F)(F)F)c1)S(=O)(=O)c1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1 +NCCN1C2=C(C(=O)Nc3ccccc3F)C(=O)CCN2c2ccc(F)cc21 +CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2C3CCCC32)cc1F +CCC(CC1(C)CC(CC)C(CC(=O)OC)OO1)C(=O)OC +O=C(c1ccc(I)cc1NS(=O)(=O)c1cccc2nccnc12)N1CCOCC1 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(S(=O)(=O)NCCC(=O)O)cc2C)ncn1 +CCCS(=O)(=O)N1CCN(C2(CNC(=O)c3c(F)cccc3F)CCC(F)(F)CC2)CC1 +COc1cc(F)cc(OC)c1C1CCCC(=O)N1Cc1ccc(OC(F)(F)F)cc1 +N=C(N)Nc1ccc(C(=O)Oc2ccc(CCC(=O)N(CC(=O)O)Cc3ccccc3C(=O)O)c(Cl)c2)cc1 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+Cc1ccccc1-c1ccc(OC(Cc2ccccc2)C(=O)O)cc1 +Clc1ccc(-c2ccc(C3=NOC(c4ccc(-c5cncnc5)cc4)N3c3ccc(N4CCNCC4)cc3)o2)cc1 +CCCCCCCCCCCCc1c(-c2ccc(O)c(O)c2)oc2c(OC)c(OC)cc(OC)c2c1=O +CCOC(O)=C1C(COCCNC(=O)c2cccnc2)=NC(C)=C(C(=O)OC)C1c1ccccc1Cl +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CNC1)C2c1ccc(Sc2nc3c(F)cccc3[nH]2)o1 +CC(C)(O)C1CCN(c2nc(NC3CCCNC3)c(-c3ccc4ccccc4n3)c(=O)[nH]2)C1 +CCC(=NNC(=O)c1cc2ccccc2cc1O)c1cc2c(F)c(F)c(F)cc2[nH]1 +C1=C(c2c[nH]c3ncccc23)CCN(CCOc2cccc3ncccc23)C1 +CC1C=CC(=O)C(O)C(O)CC=Cc2cc(NCC(=O)O)cc(O)c2C(=O)OC1C +O=C(Cc1cccc(Br)c1)NC1CCN(Cc2ccccc2)CC1 +NC(=O)CC(NC(=O)C(N)CCCN=C(N)N[N+](=O)[O-])C(N)=O +CC(C)(C)C1CCC2(CC1)CN(c1cccc(OC(F)(F)F)c1)C(=O)N2Cc1ccc(C(=O)NCCC(=O)O)cc1 +CS(=O)(=O)CCNC1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)CC1 +COc1cccc(NC(=O)N2CCN(c3ncnc4[nH]cc(C)c34)CC2C)c1 +Cc1cc(Nc2nccc(-c3cn(C)cn3)n2)cc2cc(C(=O)N3CCN(CCN4CCOCC4)CC3)[nH]c12 +Cc1cccc(-c2nc(C3CC3)ccc2CNC(=O)C(C)c2ccc(CNS(C)(=O)=O)c(F)c2)c1 +Cc1ccccc1OCC(O)CNC1CCC(NCC(O)COc2ccccc2C)CC1 +CC1CN(Cc2c[nH]nc2-c2ccc(C(N)=O)[nH]2)CCN1c1ccc(C(F)(F)F)cn1 +CCNC(=O)C1CCC(NC(=O)c2cc3cc(Cl)ccc3[nH]2)C(NC(=O)c2nc3c(s2)CN(C)CC3)C1 +CC(CN1CCN(C)CC1)NC(=O)CC1CNC(=O)c2cc(-c3cccc(Cl)c3)cn21 +O=C(Nc1ccc(C(=O)N2CC3C4CCC(C4)N3Cc3cc(Cl)ccc32)cc1)c1ccccc1F +CC1(C)OC(=O)C(Sc2ccccc2)=C1c1ccc(S(C)(=O)=O)cc1 +O=C1C(Cl)=C(N2C(=O)CCC2=O)C(=O)c2ccccc21 +COC1Cc2sccc2C2(CCN(Cc3ccc(F)cc3)CC2)O1 +O=C1C2=NCC3(CCCC3)CN2c2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc21 +CCN(CC)C(=O)Cc1c(-c2ccc(OCCF)cc2)nn2c(C)c(Cl)c(C)nc12 +O=C(Nc1ccnc(NC(=O)C2CC2)c1)c1c(Cl)cccc1Cl +CNC(=O)c1ccc(-c2ccc3c(c2)CCn2c-3cc(OCC3COc4ncccc4O3)nc2=O)cn1 +O=C(O)c1cncc(-c2cccc(NCCNCC(O)c3cccc(Cl)c3)c2)c1 +CCOC(=O)c1cnc(N2CCN(C(=O)Nc3cccc(Cl)c3)CC2)c(Cl)c1 +NC(COc1cncc(-c2ccc3c(Cl)nccc3c2)c1)Cc1c[nH]c2ccccc12 +Nc1ccc(-c2ccc3c(c2)C(O)(C(F)(F)F)c2ccccc2-3)cc1 +Cc1cccc(-n2cnc3cc(C(=O)N4CCC(Br)CC4)ccc32)c1 +CP1(=O)OCC2(CCCC3(S(=O)(=O)c4ccc(Cl)cc4)c4c(F)ccc(F)c4OCC23)CO1 +O=c1c2c3n(c(=O)cc2[nH]n1-c1ccccc1Cl)CCCN(Cc1ccc(Cl)cc1)C3 +CCNC(=O)c1ccccc1CCC(SCC(CC)C(=O)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 +COc1cc(Nc2nc(-c3ccc4cn[nH]c4c3)cn3ccnc23)ccc1N1CCOCC1 +O=C(O)c1ccc(N2C(=O)C3ON(c4ccccc4)C(c4ccccc4[N+](=O)[O-])C3C2=O)cc1 +CCOC(=O)c1[nH]c(Br)c(-c2ccc(OC)c(OC)c2OC)c1Br +CN1CCN(C(CN2CCN(CCCCc3cccc4ccccc34)CC2)c2ccccc2)CC1 +Cc1cn(-c2ccc3n(c2=O)CCN(Cc2cn(C)c4c(F)cc(C(F)(F)F)cc24)C3=O)cn1 +CCCCN(CC(C)(O)c1ccccc1)S(=O)(=O)c1ccc(O)cc1 +COc1cc(C2C(C#N)=C(N)Oc3cc(N(C)C)ccc32)cc2c1OCO2 +CCCCCC(Cc1ccc(C(=O)NCCC(=O)O)cc1)C(=O)c1cc2cc(OC)ccc2n1-c1cccc(C(F)(F)F)c1 +Nc1nccc2ccc(C(=O)NC(C(=O)N3CCN(c4ccncc4)CC3)c3ccccc3)cc12 +COCCOCCOCCOCCOCCOCCOCCOCCOCc1cn(CCCCC(NC(=O)NC(CCC(=O)O)C(=O)O)C(=O)O)nn1 +COc1ccccc1CN(C(=O)CF)c1ccccc1OC1CCCC1 +COc1cc(OCc2csc(-c3ccc(C(=O)N(C)C)cc3)n2)c2cc(-c3cn4nc(C)ccc4n3)oc2c1 +Cc1nc(C(F)(F)F)c(C=CC=CC(=O)C=Cc2nccn2C(C)C)s1 +c1cncc(CNc2ccn3ncc(-c4ccc5ccccc5c4)c3n2)c1 +Cn1nc(-c2ccccn2)cc1NC(=O)c1nc(C2CC2)cnc1Nc1cncnc1 +CC(C)CC(N)c1ccccc1N1CCN(C(=O)C(C)Cc2ccc(Cl)cc2)CC1 +O=C(O)CCCCc1cc2cc(C(=O)NC3CCCc4cc(F)ccc43)ccc2c(=O)n1-c1ccc(F)cc1 +CC(=O)Nc1cccc(-c2cc(C(C)Cc3n[nH]c(=O)c4c3CCCC4)ccc2F)c1 +CC(C)(C)C(=O)Oc1ccc2nc(S(N)(=O)=O)sc2c1N +CC(=O)NC(C)c1ccc(CN2CCc3cc(OC(C)C)ccc3C2)cc1 +BrC(COc1cccc2c[n+](Cc3ccccc3)ccc12)CN(Cc1ccccc1)Cc1ccccc1 +CCC(CO)Nc1nc(NCc2ccc(-c3ccccn3)cc2)c2ncn(C(C)C)c2n1 +CCN(CC)c1ccc(NC(=O)c2c(-c3c(Cl)cccc3Cl)noc2C(C)C)cc1 +CCC1C(C)CC2C(=O)OC(C)C2C1C=Cc1ccc(-c2cccc(C#N)c2)cn1 +CCCC1(CC(=O)O)OCCc2c1[nH]c1c(C)c(OC(C)C)cc(C#N)c21 +Nc1ncc(-c2ccc(C3(c4noc(-c5cncnc5)n4)CCC3)cn2)cn1 +O=C(Cn1c(Cl)cnc(NCC(F)(F)c2cccc[n+]2[O-])c1=O)NCc1c(F)cccc1F +CCCCc1nn(Cc2cccc(C)c2)c(=O)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +O=C(O)COc1ccc(Cl)cc1C#Cc1ccccc1C(F)(F)F +Cc1cccc(C)c1-c1noc(C)c1NC(=O)NCc1c(F)cccc1Cl +Cc1ccccc1CSc1nc(NC(CO)CC(C)C)c2sc(N)nc2n1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(N3CCN(C)CC3)cc2)c1 +Cn1c(SCCCN2CCOC(c3ccc(C(F)(F)F)cc3)C2)nnc1-c1cncc(C(N)=O)c1 +O=C(O)c1nccc(-c2ccc(OCCN3CCOCC3)c(Cl)c2)n1 +O=C(c1ccc(-c2nc(Cc3cccs3)no2)s1)C(F)(F)F +O=C(C1CCc2c(sc3ncnc(Nc4ccc5[nH]c(=O)sc5c4)c23)C1)N1CCN(CC2CC2)CC1 +CN(Cc1ccnn1C)C(=O)c1cc(C#N)ccc1C1C2=C(CCC2=O)N(c2cccc(C(F)(F)F)c2)C(=O)N1C +CCOc1ccc(Cc2nc3cc(NC(=N)c4cccs4)ccc3n2CCN(CC)CC)cc1 +COc1cccc(C2=CCN(C(=O)C3NCC4(CC4)CC3C(=O)NO)CC2)c1 +CCc1cc(Nc2nccc3nc(-c4c(Cl)cc(C(N)=O)cc4Cl)sc23)ncn1 +CN1CCN(c2nccc3cc4c(cc23)N(C(=O)c2ccccc2Cl)CC4)CC1 +O=C(O)C(=O)CC(=O)c1cccc(Cc2ccccc2Cl)c1 +Cc1ccc(Nc2ccc3c(c2)C(=CNc2ccc(CN4CCCCC4)cc2)C(=O)NC3=O)cc1 +c1ccc(-c2nc(-c3ccco3)[nH]c2-c2ccccc2)cc1 +CCOC(=O)C1CCCN1c1c(C(=O)NCc2ccc(F)cc2F)c(=O)n(O)c2ncccc12 +CCCCCCCCCCCCCC(CC(=O)NO)C(=O)NC(C(=O)NC)C(C)(C)C +CCCn1c(=O)c2[nH]c(-c3cc(OCc4nc5cc(Cl)c(F)cc5[nH]4)no3)nc2n(CCC)c1=O +CCCc1sc(-c2ccc(F)c(OCCO)c2)nc1CSc1nc(N)cc(N)n1 +CC(NC(=O)c1cncs1)c1ccc(OC2CCN(c3ccnc(N(C)CC(F)F)n3)C2)cc1 +C#CCNC(=O)C(C)Oc1cc(F)ccc1Nc1ncnc2cc(N=S(C)(C)=O)cc(C)c12 +O=C(Nc1cccc2c(=O)cc(-c3nnn[nH]3)oc12)c1ccc(OCCCCc2ccccc2)cc1 +c1ccc(CN2CCCC(n3nnc4cnc5[nH]ccc5c43)C2)cc1 +O=C(C=Cc1cccn(Cc2cccc(Br)c2)c1=O)NO +c1ccc(CCCN2C3CCC2CC(CCOC(c2ccccc2)c2ccccc2)C3)cc1 +O=C(NCCCCn1cnc([N+](=O)[O-])n1)c1ccc(OC(F)(F)F)cc1 +CCOC(=O)C(C)(C)NC(=O)C(O)C(N)CC1CCCCC1 +Cc1cc(Cc2ccc(C(=O)NC3(CC(=O)NO)CCOCC3)cc2)c2ccccc2n1 +COc1ccc(C(=O)C=Cc2cccnc2)c(OC)c1OC +COc1[nH]cc(C(=O)c2ccc(-c3ccccc3)cc2)c(=O)c1OC +O=C(NCCCO)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2[nH]c1=O +COc1cc(Nc2nccc(N3CCCC(C(=O)NCc4ccc(C)cc4)C3)n2)cc(OC)c1 +CSc1ccc(C(=O)Nc2c(Cl)cncc2Cl)c2cc(C(F)(F)F)nn12 +COCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ccnc(N(C)CC(F)F)n4)C3)cc2)s1 +O=C(c1ccccc1-c1ccco1)N1CCC2CN(c3cnc4ccccc4n3)C2C1 +CNc1nnc(-c2ccc3[nH]cc(-c4cccc(OC5CCC5)n4)c3c2)s1 +Cc1c(C(=O)NC2CCCCCC2)nc(-c2ccc(Cl)cc2Cl)n1-c1ccc(Cl)cc1 +COCCN(c1sc2ccccc2c1C)S(=O)(=O)c1ccccc1 +Cc1noc(NS(=O)(=O)c2ccccc2C(F)(F)F)c1C +COc1cccc(NC(=O)c2ccc(S(=O)(=O)N3CC(C)CC(C)C3)c(F)c2)c1 +COC1OC(C(=O)O)C(SC2OC(C(=O)O)C(OC3OC(C(=O)O)C(O)C(O)C3O)C(O)C2O)C(O)C1O +CCCn1c(SCc2cc([N+](=O)[O-])ccc2OC)nc2cc(NC(=O)NC(C)(C)C)cc(C(=O)O)c21 +COC(C)(c1ccc(F)cc1)c1ccc(C(=O)NCCCCCCC(=O)NO)cc1 +COC1Oc2c(Cl)cc(Cl)cc2C(=O)C1=CNc1ccccc1S(N)(=O)=O +COc1cc2nc(-c3ccc(N4CCOCC4)cc3)cc(O)c2cc1-c1cnco1 +OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cn[nH]c1 +O=C(O)CCCC1c2ccccc2CC1NC(=O)c1cc2sc(Cl)c(Cl)c2[nH]1 +CNc1cc2c(N(C)C3Cc4ccccc4C3)ncnc2cn1 +O=C(NCCCO)c1ccc(NC(=O)N2Cc3ccncc3C2)cc1 +c1cc(OC2CCNC2)c2nc(-c3nnc4ccccn34)ccc2c1 +O=[N+]([O-])c1ccc(Nc2nccc(-c3ccc(Cl)c(Cl)c3)n2)cc1 +Cn1cnc2cc(-c3ccc(N4CCOCC4)cc3)nc(NC3CCC(CO)C3)c2c1=O +CC(NS(C)(=O)=O)c1ccc(S(=O)(=O)c2ccc(Cl)cc2C(=O)c2ccc(Cl)cc2)cc1 +COc1cc(NC(C)(C)C(=O)Nc2nc3ccc4[nH]ncc4c3s2)ccc1Cl +Cc1cn(C2CC(O)C(C#N)(CO)S2)c(=O)[nH]c1=O +CS(=O)(=O)c1ccc(CNc2ccc(-c3c(N)nc(N)nc3C3Cc4ccccc4O3)cc2)cc1 +CN(c1cc2cc(c1)C(=O)NC(C(O)CNCc1cccc(C(C)(C)C)c1)COCC=CCCNC2=O)S(C)(=O)=O +NC(N)=Nc1ncc(Cl)c2ccc(S(=O)(=O)NC3(C(=O)N4CCOCC4)CCCC3)cc12 +Cc1cc2c(cc1C(F)(F)F)NC(=O)CC(c1cccc(-n3cncn3)c1)=N2 +COc1ccc(-c2c(C(=O)O)c(=O)n(Cc3ccccc3C)c3c2oc2ccccc23)cc1 +CC(C)(C)c1ccc(C(=CC(=O)Nc2ccc3c(c2)OCCO3)c2cccc(N)c2)cc1 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+NS(=O)(=O)c1ccc(-c2nn3cc(-c4ccc(Cl)cc4)nc3s2)cc1 +CCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C#N)cc4)cc3)nc2n(CCCOC)c1=O +O=c1oc2cc(Cc3ccccc3)ccc2n1CCN1CCOCC1 +Cc1c(OCC(F)(F)F)ccnc1COc1cccc(Nc2ncnc3cc4oc(=O)n(CCCN5CCOCC5)c4cc23)c1 +CCCCCCCc1nc(N)nc(N)c1-c1ccc(NCc2ccc(S(C)(=O)=O)cc2)cc1 +Cn1c(=O)c2c(nc(Cc3ccco3)n2C)n(Cc2ccco2)c1=O +CCCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(C(C)(NC(=O)c2ccc3ncccc3c2)C(C)C)nn1 +Cc1ccc(-c2ncc(CC(=O)Nc3ccc(-c4cnccn4)cn3)cc2C)cn1 +COc1cccc2sc(N3CCN(C(=O)c4ccc([N+](=O)[O-])o4)CC3)nc12 +CCC(CC)(Cc1nc2ccc(OCc3ccc(C)cn3)cc2n1Cc1ccc(OC(F)(F)F)cc1)C(=O)O +Cc1nc(C(CC2CC2)NC(=O)c2cnc(C3CC3)c(OCC3CC3)n2)no1 +NCC(=O)N1CCn2c(nc(-c3ccc(F)cc3)c2Nc2ccc(F)cc2)C1 +O=C(c1cccc(C(F)(F)F)c1Cl)N1CCn2c(nc(C(F)(F)F)c2-c2ccccc2)C1 +COc1ccc(F)c(-c2ccc3c(c2)C2(COC(N)=N2)C2(COC2)C2(CCC2)O3)c1 +CC1CNc2c(cccc2S(=O)(=O)NC(CCCNC(N)N)C(=O)N2CCC(C)CC2C(=O)O)C1 +NC(=O)c1nn(CC(=O)N2C(C(=O)NCC3CC3(Cl)Cl)CC3CC32)c2ccc(OCc3ncccn3)cc12 +CC(=C1SC(=N)NC1=O)c1ccc(-c2ccc(S(N)(=O)=O)cc2)o1 +COc1ccc(-n2ccc3c(sc4ncnc(NC5CC5)c43)c2=O)cc1 +CC(=O)N1CCC(C(=O)N(CCCN2CCC(C(=O)NCc3ccc(C#N)cc3)CC2)c2cccc(Cl)c2)CC1 +COc1cc2ncc(C#N)c(Nc3ccc(C)c(Br)c3)c2cc1OC +COc1cccc(-n2c(=O)n(Cc3c(F)cccc3F)c3cnc(NCC4CC4)nc32)c1 +O=C(C=Cc1ccc(O)cc1)CC1OC(CO)C(O)C(O)C1O +Cc1cc(-n2cnc3c(NCCC(F)(F)F)cc(Oc4cccc(C(F)F)c4)cc32)ccc1C(=O)NC1CC1 +CCCC(C)N1CCC(N(Cc2ccccc2)C(=O)Nc2ccc(Cl)c([N+](=O)[O-])c2)CC1 +Cn1c(=O)n(-c2ccc(C#N)cc2)c2c3cc(-c4ccc(N)nc4)ccc3ncc21 +CC1CCCN1C(=O)c1cc(C(=O)NCc2ccc(F)cc2Cl)c2n1CCOC2 +C[N+](C)(C)CC1CC(c2ccccc2)(c2ccccc2)C(=O)O1 +CC(C)C(NC(=O)OCc1ccccn1)C(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)OCc1cncs1 +CC(C)S(=O)(=O)Nc1ccc2[nH]c(Cc3ccc(Oc4ccccc4)cc3)nc2c1 +CC(C)NC(=O)N1Cc2nc(N)nc(-c3c(Cl)cc(Cl)cc3OCCCC(F)(F)F)c2C1 +O=C1NCc2cc(-c3n[nH]cc3CN3CCN(c4ccc(C(F)(F)F)cn4)CC3CO)ccc2O1 +COc1c(C)c2c(c(O)c1CCOP(=O)(O)CP(=O)(O)O)C(=O)OC2 +Cc1nc(NC(C)c2cccc(-c3cncnc3)c2)cc(-c2ccc3occ(C)c3c2)n1 +CC(C)c1sc(C2CCCC2)c(-c2ccc(F)cc2)c1C=CC(O)CC(O)CC(=O)O +C=CCNC(=O)N(O)CC1=Cc2cc(Oc3ccccc3)ccc2OC1 +Cc1cnc(Nc2nc(-c3ccccc3)nc3ccccc23)s1 +CN(C)c1ccc(OS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +Cn1c(-c2cn(-c3cccc(C(=O)NCCCO)c3)nn2)nc(-c2ccc(F)cc2)c1-c1ccncc1 +O=C(CCCN1CCN(c2ccc(F)cc2)CC1)NC1c2ccccc2C=Cc2ccccc21 +O=C1c2cc3c(cc2CN1CCC1CCN(Cc2ccc(F)cc2)CC1)OCO3 +CCCC(=O)N1CCCC(C(=O)N2CCC3(C)c4cccc(O)c4CC2C3(C)C)C1 +C=C(Br)C(=O)Nc1cccc(C=CC(=O)Nc2ccc(OC)cc2)c1 +CC1CCN(CCCCCC(=O)Nc2cc(CO)cc(Nc3ccnc4cc(Cl)ccc34)c2)CC1 +O=C(c1ccc(OCCN2CCCCC2)cc1)c1c(-c2ccsc2)sc2cc(O)ccc12 +COCCOc1ccc2c(c1)C1(N=C(N)N(CC(F)(F)F)C1=O)C1(CCC(OC)CC1)C2 +O=C(Nc1cccc(NC(=O)c2cccc(N3CCOCC3)c2)c1)c1cccc(OC2CCN(CC3CC3)CC2)c1 +CCC(=O)c1ccccc1OCC(O)CN1CCC(O)(c2ccccc2)CC1 +COc1ccc(Cn2cc(CCc3cc(OC)c(OC)c(OC)c3)c3c(C)nc(N)nc32)cc1 +Cc1ccc(N2CCC(CO)C2)nc1C(=O)Nc1c(C)cc(C(=O)O)cc1C +C=Cc1cccc(C(=O)c2c(CC)c(C)nc(O)c2N(C)C)c1 +CC(=O)Nc1ccc2c(c1)-c1ccccc1S2(=O)=O +Cc1cccc2c(=O)n(CCc3ccccc3)c(-c3ccccc3O)nc12 +COC(=O)C(C)NP(=O)(OCC1C=CC(Cn2cc(C)c(=O)[nH]c2=O)O1)Oc1ccc(F)cc1 +CNC(C)C(=O)NC1C(=O)N(Cc2c(OC)ccc3ccccc23)c2ccc(C#N)cc2N(C(=O)C2CCOCC2)C1C +Cc1nc(C#Cc2cnc(-c3cccc(C)c3C)nc2)cs1 +Cc1nnc(SCC(=O)Nc2ccccc2Br)n1-c1ccc(Cl)c2ccccc12 +CCN(CC(=O)NC(CC(=O)O)C(=O)NCCC1CCCCC1)C(=O)CCCC1CCNCC1 +Cn1ccc2ccc3c4[nH]c5cccc(F)c5c4c4c(c3c21)C(=O)NC4=O +CCOC(O)=C1C(COCCN)=NC(C)=C(C(=O)OC)C1c1cccc(-n2ccnc2)c1 +Cc1ccccc1C(=NOCCN1CCC=C(C(=O)O)C1)c1ccccc1C +COc1cc(C(=O)c2cc3c(OC)cccc3o2)cc(OC)c1OC +COc1cc(N2CCN(C3CCN(c4ccc(F)c5c(OC)cc(C(F)(F)F)nc45)CC3)CC2)c2ncccc2c1 +CCOc1nc2nn(C)cc2c2nc(-c3ccco3)nn12 +CC(CCC(=O)NNc1ccc(S(N)(=O)=O)cc1)C1CCC2C3C(=O)CC4CC(=O)CCC4(C)C3CC(=O)C12C +CC(OP(N)(=O)N(CCCl)CCCl)c1ccc([N+](=O)[O-])cc1 +Cc1cc(-c2ccc(C(=N)N)cc2)cn2cc(-c3ccc(C(=N)N)cc3)nc12 +O=C(O)C1=CCCN(CCOC(c2ccc(Cl)cc2)c2ccc(Cl)cc2)C1 +Cc1c(Nc2c(C#N)cncc2C=CCCN2CCCCC2)ccc2[nH]ccc12 +CCOc1ccc(C(=O)Nc2cccc(Cc3n[nH]c(=O)c4c3CCCC4)c2)cc1OCC +N#Cc1ccc(C(c2cccnc2)N2CCC(NC(=O)c3ccc(C(F)(F)F)cc3F)CC2)cc1 +O=[N+]([O-])c1ccc(-c2ccc(OCc3nnc(SC4CCCC4)n3-c3cccnc3)cc2)cc1 +CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(C)=O)cc1 +Cc1cc(NC(=O)Nc2ccc(N(C)C)cc2)c2cc(F)cc(F)c2n1 +CCCCOC(=O)NS(=O)(=O)c1ccccc1-c1ccc(Cn2c(CCC)nc(CC)c2C(=O)OC)c(Br)c1 +CC1COCCN1c1cc(C2(S(=O)(=O)CCCO)CC2)nc(-c2ccc(NC(=S)NCCO)cc2)n1 +COc1ccc(C=C2SC(=Nc3ccccc3)NC2=O)cc1 +COc1cc(N2CCC(c3nc(C(=O)Nc4nc5cc(C(=O)c6ccccc6)ccc5[nH]4)cs3)CC2)nc(OC)n1 +Cc1cc(CC(C(=O)O)c2cn(CCCC(C)C)cn2)cnc1N +Cc1cn(C2CC(N=[N+]=[N-])C(COC(=O)C(N)Cc3ccc(O)cc3)O2)c(=O)[nH]c1=O +Cc1[nH]nc2c1C(c1cc(-c3cccc(CCC(=O)O)c3)cc(C(F)(F)F)c1)(C(C)C)C(C#N)=C(N)O2 +CC(=N)C(C#N)=C(O)CSc1nnnn1-c1ccc(C)cc1 +COC(=O)C1CC(OC)C(=O)C2C1(C)CCC1C(=O)OC(c3ccoc3)CC12C +CCCCN(C)Cc1ccc2c(NC(=O)c3ccc(C)s3)c(C(=O)OC)sc2n1 +Cc1ccc(-c2ccc(N3C(=O)C(=O)C(C(=O)CC(C)C)C3c3cccnc3C(=O)N(C)C)cc2)s1 +CCc1ncnc(-c2ccc(C(=O)N(C)CC3CCCN(C)C3)c(F)c2)c1C#Cc1ccc(N)nc1 +Cc1noc(C)c1CC(=O)NCc1ccc(Cl)c(C(F)(F)F)c1 +CCCCCCCCCN1NN=C(NC(=O)Nc2c(C(C)C)cccc2C(C)C)N1 +CC(C)(CO)NCc1cccnc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2Cl)NC(=O)CCN)CC1 +COc1ccc(-n2ccc(C(=O)c3cc(OC)c(OC)c(OC)c3)c2)cc1OC(C)C +COC(=O)c1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +CCc1ccc(-c2ccc(NC(=O)Oc3ccccc3F)cc2)cc1 +CCC(C(=O)O)C1CCc2cc(OCCc3nc(-c4cccc(C)c4)oc3C)ccc21 +O=C(NC1CC2CCC(C1)N2Cc1ccccc1)c1ccc2ccccc2c1 +CCC(NC(=O)c1cc(C(=O)NC(C)c2ccc(F)cc2)c2n1CCOC2)c1ccccc1 +Cn1cc(C(=O)Nc2cc(F)c(CC(=O)N3CC(O)CC3COC3CCC(C(=O)O)CC3)cc2Cl)c2ccccc21 +Cc1cccc(Nc2nccc(-c3ccc(Br)cc3)n2)c1 +ON=C1CCC(C2CCCC2)=C1c1ccc2c(c1)OCO2 +CC(C)(C)CC(=O)OCC1(CO)CC(=Cc2ccc(Cl)cc2)C(=O)O1 +COCCCn1c(NC(=O)c2ccc(C#N)cc2)nc2cc(CN3CCOCC3)ccc21 +N#CC1CCCN1C(=O)CNC1CC2CN(C(=O)N3CCCCC3)CC2C1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(N4C(C)COCC4C)n3)C2)cc1 +CC(=O)Oc1cccc2c1C(=O)c1c(-c3ccc(F)cc3)noc1C2=O +NC(=O)c1ccc(Oc2ccc(CCNCc3cccc(Cl)c3)cc2Cl)nc1 +CC(C)CN(CC(=O)NO)S(=O)(=O)c1ccc(OCC2CCCCC2)cc1 +CNC(=O)NC1CCC(OCc2cc(C(F)(F)F)cc(C(F)(F)F)c2)C1c1ccccc1 +NC1=NC2(CO1)c1cc(-c3cccnc3F)ccc1Oc1c(F)cc(-c3ccccn3)cc12 +COCCCCN1CCN(C(=O)c2cc3c(cc2C)[nH]c(=O)c2cnn(C4CCC4)c23)CC1 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+CCc1cc2c(cc1N1CCN(CC3(O)CCOCC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +O=C(O)CC(CC1CCN(C(=O)CCCc2ccc3c(n2)NCCC3)CC1)c1ccc2c(c1)OCO2 +COc1ccc(-c2ccc3c(N)c(C(=O)Nc4ccc(SC)cc4)sc3n2)cc1 +CC(C)C(=O)N1CCC(Nc2ncccc2-c2cnc3[nH]ccc3n2)C1 +O=C1c2nnc(-c3ccc(F)cc3)n2CCN1Cc1cccc(C(F)(F)F)c1Cl +Cc1cc(C(F)(F)F)cc(-n2ncc(-c3ccc4cc(CCN5CCCC5C)ccc4n3)c2C)n1 +CCCc1cc(=O)[nH]c(SCC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1 +Nc1nc2c3ccc(NCCN4CCCC4)cc3nc(Cc3ccc4c(c3)OCO4)n2n1 +COc1ccc(NC(=O)Nc2cc3ccc(OC4CCN(C)CC4)c(C)c3oc2=O)cc1-c1ccccc1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)c1ccc(Cc2ccc(Cl)cc2)cc1 +COc1cc2c(=O)n(CCc3ccc(S(N)(=O)=O)cc3)c(S)nc2c(OC)c1OC +NCCCCCOCC1OC(OCCc2c[nH]c3ccccc23)C(OCc2ccccc2)C(OCc2ccccc2)C1OCc1ccncc1 +COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(F)c(OC(F)(F)F)c4)cc3)c(=O)c2cc1Cl +CCCN(CC=CC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1)CCC +CCC1=CC2Cc3nc4cc(F)cc(F)c4c(N)c3C(C1)C2 +COc1ccc(OCC2CCC3CN(c4ncccn4)CCN3C2)cc1 +CC1Cn2c(nnc2-c2cnn(C)c2)C(=O)N1Cc1cccc(C(F)(F)F)c1Cl +CC(Cc1ccc(C#Cc2cnc(OC3CCC3)nc2)cc1)NC(=O)C1CC1 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+Nc1ccc(S(=O)(=O)NCCOc2ccc3c(c2)C(C2(c4ccc(Cl)cc4)CCC2)NCC3)cc1 +CCOc1nc(NC(=O)Cc2cc(OC)c(Br)cc2OC)cc(N)c1C#N +CCOC(=O)Cn1cc(-c2cnc(NC(=O)C(CC3CCOCC3)c3ccc(S(=O)(=O)C4CC4)cc3)s2)nn1 +COc1ccc(-c2cncc(-c3cc4c5c(c3)CCN5C(=O)CC4)c2)cc1 +O=C(O)c1cc(-c2ccc(Br)cc2)nc2ccccc12 +Cc1c(F)c(N)cc(C(=O)Nc2cc(-c3ccc(NC(=O)C(C)C)cc3)ccc2N2CCN(C)CC2)c1Cl +CC(=O)Nc1cc(NC(C(=O)Nc2nc3c(C(F)(F)F)cc4[nH]ncc4c3s2)c2ccccc2)ccc1Cl +O=C(O)C(C1CCCCC1)N1CC(CN2CCC(c3cnc(-c4ccccc4)[nH]3)CC2)C(c2ccccc2)C1 +COc1cccc(CNc2n[nH]c(-c3cccnc3Nc3cc(OC)cc(OC)c3)n2)c1 +COC(=O)CNc1nc(NCC(=O)OC)nc(NCc2ccc(S(N)(=O)=O)cc2)n1 +Cc1csc(NC(=O)NC23CC4CC(CC(C4)C2)C3)n1 +CNc1nc(Cc2ccccc2)nc(Nc2ccc(-n3cnc(C)c3)c(OC)c2)n1 +CS(=O)(=O)CCNCc1ccc(-c2ccc3ncnc(Nc4ccc(OCc5ccccc5)cc4)c3c2)o1 +O=C(c1ccco1)N1CCN(c2cnn(CCCCN3CCN(c4ccccc4Cl)CC3)c(=O)c2Cl)CC1 +CC(C)c1cccc(NC(=O)Nc2cccc(-c3cccc4[nH]nc(N)c34)c2)c1 +O=[N+]([O-])c1ccc(SC(=S)N2CCN(Cc3ccc(Br)cc3)CC2)c([N+](=O)[O-])c1 +COc1ccc(Nc2c(C(N)=O)cnc3cc(-c4ccncc4)ccc23)cc1F +COCCOc1cccc2c(NCc3ccccc3)nc(-n3c(C)nc4ccccc43)nc12 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCC(=O)N3CCC3)no2)cc1C#N +O=C(NCCC(F)CN1CCN(c2cccc(Cl)c2Cl)CC1)c1cc2ccccc2s1 +CC(C)Nc1cc(-c2c(-c3ccc(F)cc3)nn3cc(C(N)=O)ccc23)ccn1 +COc1ccc(-c2nnnn2-c2cc(Br)c(OC)c(Br)c2)cc1O +Cc1ccsc1C(=O)n1nc(Nc2ccc(S(N)(=O)=O)cc2)nc1N +N#CC(=Cc1ccc(O)c(O)c1)C(=O)OCCc1cccs1 +O=C(CCc1ccc(-c2ccc[nH]2)cc1)Nc1ccccc1C(=O)O +CC(C)(C)c1ccc(-c2noc(CCC(=O)NC3CCCC3)n2)cc1 +COc1ccc2nc(C(C)Cc3cc4c(cc3Cl)OCO4)[nH]c2c1 +Cc1cc(CNC(=O)NCC23CC4CC(CC(C4)C2)C3)on1 +COc1ccccc1Oc1c(NS(=O)(=O)c2ccc(C(C)(C)C)cc2)nc(NCCO)nc1OCCOc1ncc(Br)cn1 +COc1ccc2c(c1)NC(=O)Cc1cnc(Nc3ccc(OC)c(O)c3)nc1-2 +CCOC(=O)c1nn2c(=O)[nH]c3ccccc3c2c1C(=O)OCC +NS(=O)(=O)c1ccc(N2C(=O)c3cccnc3C2=O)cc1 +CN(C)CCCON=C1c2ccccc2-c2nc3c(C(=O)NCCN(C)C)cccc3nc21 +COc1cc2ncnc(N3CCN(C(=O)Nc4ccc(Oc5ccccc5)cc4)C(C)C3)c2cc1OC +OC1(C(F)(F)C(F)(F)F)CCCc2c1[nH]c1cc(Cl)c(Cl)cc21 +CC1(C)CN(Cc2ccc(F)cc2)C(=O)C(C2=NS(=O)(=O)c3cc(NS(C)(=O)=O)ccc3N2)=C1O +Cc1ccc(C(=O)C=Cc2ccc(C(=O)O)cc2)o1 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+COc1ccc(C=NNc2ccnc3c(OC)cccc23)cc1 +Cc1cccc2c(C(=O)C(C)(C)CSc3nnc(-c4ccc5ccccc5n4)n3CCCCN)c[nH]c12 +O=C(NO)C(CCCc1ccccc1)CS(=O)(=O)c1ccc(Cc2ccccc2)cc1 +CCOC(=O)C1C2CCC(CC1c1ccc(-c3cccn3CC)cc1)N2 +CN=C(Cc1c(Cl)cccc1Cl)NC(=O)Nc1ccc(C#N)cc1 +Cc1ccc([N+](=O)[O-])c(OC(CCN2CCC(n3c(O)nc4ccccc43)CC2)C(C)C)c1 +CSc1nc2cc(S(=O)(=O)NCc3ccc(F)cc3)ccc2n1Cc1ccccc1 +COCC(=O)Nc1nc(C)c(C(=O)NC(C)c2ccc(OC3CCN(c4ccnc(OCC5CC5)c4)C3)cc2)s1 +O=C(NCCc1ccc(Cl)c(Cl)c1)c1cccc(Cc2n[nH]c(=O)c3c2CCCC3)c1 +CC(C)(O)C#Cc1ccc2c(c1)c1cc(C#CC3CC3)ccc1c1nc(-c3c(C#N)cccc3C#N)[nH]c21 +Cc1c(CC(F)(F)F)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)cc1 +Cc1ccccc1C(Nc1ccc(Cl)cc1C(F)(F)F)C(=O)CCc1ccncc1 +COc1ccc(C(=O)OCC2(CO)CC(=CC3CCCCC3)C(=O)O2)cc1 +COc1cc2ncc3c(c2cc1-c1cc(C(F)(F)F)nn1C)n(-c1ccc(C#N)cc1F)c(=O)n3C +CN1CCc2nc(NC(=O)c3cccc(OCC(=O)Nc4ccc(C#N)cc4)c3)sc2C1 +O=C(c1ccc(C(=O)C2CC2)c(C(=O)O)c1)c1ccc(N(CC2CC2)c2ccc(Cl)cc2)cn1 +O=C1C(=O)N(c2ccccc2Br)CCN1Cc1ccc(F)cc1Cl +Cc1nn(C)c(C)c1CN(C)S(=O)(=O)c1ccc2ccccc2c1 +O=C(c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F)N1CCN(Cc2ccccc2Cl)CC1 +CC(C)(C)CCC1(C(=O)c2ccc(Cl)c(Cl)n2)CCNC1 +O=C(c1ccncn1)N1CCC2(CCN(Cc3ccccc3Oc3ccccc3)CC2)CC1 +N=C(N)NCCCC(=O)N1CCCC1C(=O)NC(CC(=O)O)C(=O)NCc1ccccc1 +CCCC(NC(=O)C(=O)C(C)(C)C)C(=O)Nc1ncc(C(C)C)s1 +CN1C(=O)c2[nH]c(Cc3ccc(-c4ccccc4)cc3)nc2N2C1=NC1CCCC12 +CN1CC(=O)N(c2cc(Cc3nnc(O)c4ccccc34)ccc2F)C(=O)C1 +CC(C)(C)OC(=O)NC(Cc1ccccc1C(F)(F)F)C(=O)NCc1nc2cccnc2n1CC(F)(F)F +Nc1ccc(S(=O)(=O)Nc2cccc(-c3ccc(C4CC4NC4CCC(N)CC4)cc3)c2)cn1 +Cc1cccc(C)c1Oc1c(C(=O)N2CCNC(C)C2)c2ncccc2n1C1CCCCC1 +Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1Cl +CCOC(Cc1ccc(OCC=C(c2ccccc2)c2ccc(-c3ccccc3)cc2)cc1)C(=O)O +CN(CCCN1CCc2oc3ccccc3c2C1)CCc1ccccc1 +Cc1cc(COc2c(C)cccc2-c2csc(N3CCC4(C(=O)O)CC4C3)n2)c(C)c2c1CN(C1CCCOC1)CC2 +CC(NC(=O)c1c[nH]c2ncc(-c3nn(C)c4cc(C(C)(C)C)ccc34)nc12)C(=O)N1CC(C#N)C1 +C=CC(=O)Nc1cccc(-c2c[nH]c3nccc(Cl)c23)c1 +Cc1cccc2nccc(NCCCNCCNc3ccnc4cccc(C)c34)c12 +CC1CCCCN1C(=O)c1cc(N)n2nc(-c3ccc(Br)o3)nc2c1 +CCCc1nc(C(=O)NCCCN2CCN(c3cccc(Cl)c3C)CC2)c(C)n1-c1ccccc1OC +COC1N=C(c2ccccc2F)c2cc(C#CCN3C(=O)CCc4ccccc43)ccc2-n2c(C)nnc21 +Cn1ncc(-c2nn(C)c3ncnc(N4CCC4)c23)c1-c1ccccc1 +Cc1cc(C(=O)NCCCN2CCN(c3cccc(C)c3C)CC2)nc(C(C)(C)C)n1 +COc1ccccc1N1CCN(CCCCNC(=O)OC(C)(C)C)CC1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)c3ccc(F)c(F)c3)CC2)C1 +CCN(CC)CCCOc1ccc2c3c(nccc13)-c1ccccc1C2=O +COc1ccc2c(c1)CCn1c-2cc(OCC2COc3ccccc3O2)nc1=O +COc1ccc2cc(CCc3c(C(=O)O)[nH]c(=O)[nH]c3=O)c(OC)cc2c1 +COc1ccc(S(=O)(=O)N2CC(N3CCCCC3)CC2C(=O)NO)cc1 +CN1Cc2c(C3=CCN(CC(=O)N4CC(O)C4)CC3(C)C)[nH]c3nccc(c23)-c2cc(F)ccc21 +NS(=O)(=O)c1ccc(NC(=O)C=Cc2ccc(Cl)cc2)cc1 +Nc1cncc(-c2c[nH]c3ccc(-c4nnc(N)s4)cc23)n1 +CNC(=O)C(C(=O)NO)N(C)C(=O)c1ccc(-c2ccc(OCCO)cc2)cc1 +CS(=O)(=O)Nc1c(Cl)ccc2c1CCCC2c1ncc[nH]1 +CC(O)CNC(=O)CNC(=O)Cc1nc2ccc(-c3ccccc3)cc2s1 +COC(=O)C1CN(CCCc2ccccc2)CCC1c1ccc(Cl)cc1 +CCCN(C)c1nc(C)nc2c(-c3c(C)cc(OC)cc3OC)c(C)nn12 +CC(=O)c1cc(C(=O)NOC(CO)CO)c(Nc2ccc(I)cc2F)n1C +O=S(=O)(c1ccc(-c2nnn[nH]2)cc1)N(CCCCC(F)(F)F)c1sc2ccccc2c1Br +Cc1ccc(S(=O)(=O)n2ccc3ccc(N4CCN5CCCC5C4)cc32)cc1 +CC1(C)SCC(C(=O)NC(Cc2ccccc2)C(=O)N2CCCC2C(N)=O)N1C(=O)C(N)Cc1ccc(O)cc1 +COC1CC(CF)N(c2nc3cc(-c4nc(=O)o[nH]4)nc(-c4cncc(Cl)c4)c3n2CC2CCC(C)CC2)C1 +COc1cc(C(F)F)ccc1-c1nccc2cc(S(=O)(=O)Nc3nccs3)ccc12 +CCCC(=O)NCCc1c(CN2c3ccccc3CC2C)[nH]c2ccc(OC)cc12 +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1ccc(S(=O)(=O)CCCN2CCOCC2)cc1 +CCc1cc2c(cc1CC)CC(NCC(O)c1ccc(O)c3[nH]c(=O)c(C)cc13)C2 +Clc1cccc(Cl)c1Cc1sc(NCc2ccc3c(c2)CCO3)nc1-c1ccccc1 +COc1ccc(CO)cc1-c1cc(F)cc(C(CC(=O)O)c2ncco2)c1 +CC1CN(CCC(O)C2CCCC2)CCC1(C)c1cccc(O)c1 +C=CCN(Cc1ccc(N(CC)CC)cc1)S(=O)(=O)c1ccc(C)cc1 +O=C(NO)c1cnc(NCc2ccc(-c3ccccc3)cc2)nc1 +CC(C)Nc1nc(-c2cnn(CCN3CCOCC3)c2)cc2ncn(C)c(=O)c12 +C=C1CCC2C3Cc4ccc(C(N)=O)c(O)c4C2(CCN3CC2CCC2)C1 +O=C(Nc1ccc(Oc2ccccc2)cc1)N1CCN(c2ncnc3cc4ccccc4cc23)CC1 +CN(C)CCN(Cc1ccc(-c2ccc(CNCCc3ccccc3)cn2)cc1)C(=O)C=Cc1ccccc1 +c1ccc(-c2cccc(CN3CCN(c4cccc5c4OCCO5)CC3)c2)cc1 +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)N(C)c1ccc(Cl)cc1 +O=C(Nc1cnccn1)Nc1ccnc2ccc(C(F)(F)F)cc12 +O=C(NCCCCN1CCCC2c3ccc(O)cc3CCC21)c1ccc(-c2ccccc2)cc1 +COc1cccc(-c2cccn3nc(Nc4ccc(C5CCNCC5)cc4)nc23)c1 +COc1n[nH]c2cc(NC(=O)NC(C)c3ccccc3)nc(-c3n[nH]c(=O)o3)c12 +CCn1c(=O)ccc2cnc(Nc3ccc(N4CCC(CCCO)CC4)cc3)nc21 +CC(C)(C)c1ccc(C(=O)NC2CCCN(c3nc(C(N)=O)c(Nc4ccccn4)s3)C2)cc1 +CC1(C)CCc2sc(NC(=S)NC(=O)c3ccccc3)c(C(=O)O)c2C1 +N=C(N)NCCNC(=O)C=CC1=C(C(=O)O)N2C(=O)C(=Cc3ccccn3)C2S(=O)(=O)C1 +CC(C)(C)C(O)C(=O)N1CCCC1C(=O)NCc1cc(Cl)ccc1CN +COc1cc(Cc2cnc(N)nc2N)ccc1OCc1ccccc1 +CC1CN(C2CC(c3ccc(F)cc3)c3ccc(Cl)cc32)C(C)CN1C +OC(c1ccccc1)(c1ccccc1)C(c1ccccc1)N1CCOCC1 +CC1CCC(C(=O)N(c2cc(C#CC(C)(C)C)sc2C(=O)O)C2CCN(S(C)(=O)=O)CC2)CC1 +O=S(=O)(c1ccccc1)N1CCC2(CC1)OOC1(OO2)C2CC3CC(C2)CC1C3 +O=C(O)c1ccc(Nc2cc(N3CCN(C4CCCCC4)CC3)c3noc4c3c2C(=O)c2ccccc2-4)cc1 +CC(C)CC(NC(=O)C(C)NC(=O)CC(O)C(COCc1ccc(Br)cc1)NC(=O)c1c(F)cc(F)cc1F)C(N)=O +Cc1cccc(OCCCn2cnc(-c3ccccc3)c2C)c1NC(=O)NCC(C)(C)C +Cn1nnnc1-c1cccc(NC(=O)NCCCN2CCCC(Cc3ccc(F)cc3)C2)c1 +CC(=NNC(=O)c1cc([N+](=O)[O-])cc([N+](=O)[O-])c1)c1ccco1 +CS(=O)(=O)Cc1nc2ccccc2n1-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CCOC(=O)C1=C(C)NC(=O)N(C(=O)OCC)C1c1cccc([N+](=O)[O-])c1 +COc1ccc(C2(c3ccc(OC)cc3)NC(=N)N(CC3CCCCC3)C2=O)cc1 +CC1(C2CCN(c3ncc(C(F)(F)F)cn3)CC2)Cc2cc(C3=CCN(S(C)(=O)=O)CC3)ncc2O1 +CC(=Cc1ccccc1)CC(CC(N)C(=O)O)C(=O)O +CS(=O)(=O)c1cc(Cl)c(NC(=O)N2CCN3C(=O)N(C4CC4c4ccccc4)C(=O)C3C2)c(Cl)c1 +Cc1c(C(=O)Nc2nc3ccccc3[nH]2)oc2c(Cl)cccc12 +CN(CC(=O)NC(CCCCN)C(=O)C(=O)Nc1cccc(N)c1)C(=O)c1ccccc1Sc1ccccc1C#N +COc1ccc2c3c4c(c5c(ccc6ccn(C)c65)c3n(CCCN3CCC(C(N)=O)CC3)c2c1)C(=O)NC4=O +Cc1cccc(-n2c(C=Cc3ccc([N+](=O)[O-])o3)nc3ccccc3c2=O)c1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N1CCC(F)CC1)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1cccc(-c2cccc(C(CC(=O)O)c3nccs3)c2)c1Cl +CC1CN(Cc2ccccc2)CC1c1nn2c(-c3cccnc3)ncc2c(=O)[nH]1 +COc1ccc2c(c1)C(CCNC(=O)C1CCC1)CC(c1cccc(C(F)(F)F)c1)C2 +CNC(=O)c1ccc(Nc2cc(NC3CC3)n3ncc(C=C4NC(=O)NC4=O)c3n2)c(F)c1 +CON(C)C(=O)c1ccc(-c2ccc(OCC3CCN(C(=O)OC(C)C)CC3)cn2)cc1 +CC(=O)Nc1ccc(OCC(C)(O)C(=O)Nc2ccc([N+](=O)[O-])c(C(F)(F)F)c2)cc1 +COc1ccc(-c2cc3ccccc3oc2=O)cc1NC(=O)c1ccc([N+](=O)[O-])o1 +CC(C)(C)C(O)C(=O)N1CCC2CC21C(=O)NCc1cc(Cl)ccc1-n1cnnn1 +CCCCCCNC(=O)Oc1cccc(-c2ccc(C(C)C(=O)O)cc2Cl)c1 +COc1cccc(CCN2CCN(c3ccccn3)CC2)c1OCCc1ccccc1 +C[N+](C)(CCCCNC(=O)CCc1ccc(OCc2ccccc2)cc1)CCNC(=O)c1nc(Cl)c(N)nc1N +CCN(CC)CCNc1nc(Nc2ccc(C)cc2)nc(Nc2ccc(Nc3ccnc4cc(Cl)ccc34)cc2)n1 +Cn1c(=O)c2nc(C=Cc3cccc(F)c3)[nH]c2n(C)c1=O +COc1ccccc1N1CCN(CCCCNC(=O)c2cc(-c3ccco3)[nH]n2)CC1 +CC(C)CN(NC(=O)Cc1ccc(OCCN2CCOCC2)cc1)c1nc(C#N)ncc1Cl +O=C(NCC#Cc1ccc2nccc(OCC3CCCCO3)c2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +c1cncc(CNCc2ccc(CN(CC3Cc4ccccc4CN3)C3CCCc4cccnc43)cc2)c1 +C=C(C)C1CCC(C)(O)C1CC1=C(O)C(C)(CC=C(C)C)C(=O)C(C(=O)C(C)CC)=C1O +Cc1cc(Cl)c(S(=O)(=O)N2CCCCCC2)cc1OCC(=O)NC1CCCCC1 +N#CC1CC1CN(C(CCC(F)(F)F)C(N)=O)S(=O)(=O)c1ccc(Cl)cc1 +CC(=O)N1Cc2c(n(C)c3nc(-n4ccc(OCc5ccccc5)cc4=O)ccc23)CC1C 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+Cc1ccc2c(c1)C(O)C(N1CCC(c3cccc4c3OCCO4)CC1)C2 +CC(C)C1CCN(CCOc2ccc(C3Oc4ccc(O)cc4SC3c3ccc(O)cc3)cc2)C1 +CN(CCCCC1(C)COC(c2nc(-c3ccccc3)c(-c3ccccc3)[nH]2)OC1)c1ccccn1 +Nc1nccc(-c2[nH]c(C3CCNCC3)nc2-c2cccc(C(F)(F)F)c2)n1 +Cc1ccc(-n2nccn2)c(C(=O)N2CC(COc3ccc(F)c(C)c3)CCCC2C)c1 +CC1C2Cc3cc4ncnc(NCCc5ccc(-c6ccccc6)cc5)c4cc3C1(C)CCN2CC1CC1 +COc1cc2nc(N3CCN(c4ncccn4)CC3)nc(N)c2cc1OC +O=C(c1n[nH]c2c1CCN(CC(F)(F)F)C2)N1CCC(c2ccc(F)c(F)c2C(F)(F)F)CC1 +OCCN1CCN(c2cc(Nc3nccc4nc(-c5c(Cl)cccc5Cl)[nH]c34)ncn2)CC1 +CCCc1cc(=O)oc2c3c(c4c(c12)OC(C)(C)CC4)OC(C)C(C)C3O +Clc1ccccc1Cn1cc(-c2ccc3[nH]ncc3c2)nn1 +CS(=O)(=O)NCCCCCNc1nc2c(s1)CCSc1ccc(F)cc1-2 +COc1ccc(CNC(c2ccc(Cl)cc2)c2cccnc2)cc1 +O=C(C=Cc1ccc(S(=O)(=O)N2CCc3cccnc32)cc1)NO +O=S(=O)(c1ccccc1)N(Cc1ccccc1)c1ncc(C(F)(F)F)cc1Cl +CC1CN(CCCC2C3CCCCC3CC3C(=O)OC(C)C32)C(C)CN1 +O=C(c1ccc([N+](=O)[O-])o1)N1CCN(c2nc3c(F)cc(F)cc3s2)CC1 +Cn1c(=O)[nH]c2nccc(Oc3ccc(NC(=O)Nc4cccc(SC(F)(F)F)c4)c4ccccc34)c21 +COc1ccc(O)c(C(=O)c2ccc(C=CC3CCCNCC3NC(=O)c3ccncc3)cc2)c1F +CCC(CC)(COc1cc(C)c(-c2ccc(-c3ncc(C(F)(F)F)[nH]3)c(Cl)c2)cn1)C(=O)O +O=C(NC1CCN(CC(F)(F)F)CC1)c1ccc(N2CCCCC2)nc1 +CCOc1ccc2c(C(=O)NCc3ccc(F)c(F)c3)c(C(C)C)n(Cc3ccccc3)c2c1 +O=C(Nc1ccc(OC(F)(F)F)c(F)c1)c1cnc(N2CCC(CO)C2)c(-c2cncnc2)c1 +COCc1cccc(CC(O)C=CC2C(O)CC(F)C2CCSCCCC(=O)O)c1 +Cc1cn(C2CC(N=[N+]=[N-])C(COP(=O)(Oc3cccnc3)Oc3ccc(Cl)cc3Cl)O2)c(=O)[nH]c1=O +Cc1ccc2c(c1)nc(N1CCN(Cc3ccccc3)CC1)c1cccn12 +COc1ccc(COC(=O)C2=C(C)NC(=O)NC2c2ccc(F)cc2)cc1 +Cc1cnc(-c2ccnc3c(C(=O)C(=O)N4CCN(C(=O)c5ccccc5)C(C)C4)c[nH]c23)s1 +COC(C)C(=O)Nc1ccc(F)c(C23COCC2S(=O)(=O)C(C)(C)C(=N)N3)c1 +Cc1ccc2cc(C(=O)NC3(C(=O)NC(CCCN4CCC(N5CCOCC5)CC4)Cc4ccccc4)CCCC3)sc2c1 +CN1c2ccccc2C(=O)N2CCc3c(n(C(=O)c4cccc(Cl)c4)c4ccccc34)C21 +CN1CC(COc2ccc(C(=O)Nc3cc(CC(=O)O)ccc3F)c(Cl)c2)Oc2ccccc21 +CCCC(=O)c1c(C)[nH]c2c1C13CC1CN(C(=O)c1cc4cc(OC)c(OC)c(OC)c4[nH]1)C3=CC2=O +NC(=O)c1c(Oc2cccc(NS(N)(=O)=O)c2)cc(F)c(F)c1Nc1ccc(I)cc1F 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+O=C(O)C(=Cc1ccc(Oc2ccccc2Br)cc1)NC(=O)c1ccc(F)c(F)c1 +CC(NC(=O)OCc1ccccc1)C(=O)Nc1ccc(C2SC(=Nc3ccc(C#N)cc3)N(Cc3ccco3)C2=O)cc1 +CC(C)Nc1nc(-c2ccc(C3(O)CCCC3)cc2)cc2ncn(C)c(=O)c12 +CC(NCCCCNc1ccnc2cc(Cl)ccc12)C12CC3CC(CC(C3)C1)C2 +CC1(C)OC(=O)N(c2ccc(C(=O)Nc3cccc4cccnc34)cc2)C1c1ccncc1 +COCCNc1cc(-n2c3c(c4ccccc42)C(=O)CCC3)ccc1C(N)=O +Cc1cc(C(Nc2ccc(F)c(CN3CC(C(=O)O)C3)c2)C(F)(F)F)ccc1Cl +CC(=O)c1ccc(-c2ccc(-c3cc(C(=O)NCC4CCC(C(=O)O)CC4)sc3F)cc2)cc1 +COc1ccc(C(=O)Nc2cccc(C(CCN(C)C(=O)OC(C)(C)C)Nc3ncnc4c(C(N)=O)cccc34)c2)cc1 +CC(c1ccc(F)cc1)N1C(=O)OC(Cc2ccccc2)(c2nc3cc(-c4cccnc4)ccc3[nH]2)C1=O +O=C(NC1CCCC(c2nc3ccccc3[nH]2)C1)c1ccc2c(c1)OCCO2 +Cc1cc(Oc2cccc(N(Cc3cccc(OC(F)(F)C(F)F)c3)CC(O)C(F)(F)F)c2)ccc1Cl +CCOc1ccc2c(c1)CCC2Nc1ncnc2c1ncn2C1OC(CO)C(O)C1O +CCOC(=O)c1cnn2c1n[n+]([O-])c1ccc(Cl)cc12 +CCC(=O)N1Cc2cc(OC)ccc2C(Cc2c(Cl)cncc2Cl)=N1 +CC1(C)CCc2c(C(=O)Nc3cnn(C(c4ccccc4)C4CCS(=O)(=O)C4)c3)n[nH]c2C1 +O=C(NCCN1CCC2(CC1)C(=O)NCN2c1cccc(F)c1)c1cnc2ccccc2c1 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+CC(C)C(=O)N1CCn2cc(C3=C(c4cnc5ccccn45)C(=O)NC3=O)c3cccc(c32)C1 +CC(C)Oc1ccccc1N1CCN(CC(O)CNC(=O)c2cccnc2Nc2ccc(Cl)cc2)CC1 +CCCCCCNC(=O)n1cc(-c2ccccc2)c(=O)[nH]c1=O +Cc1ccc(NS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1C +CC1CN(CCCn2c3ccc(Br)cc3c3cc(Br)ccc32)CC(C)N1 +O=c1cc(-c2ccccc2)oc(O)c1C(CC1CC1)SC1CCCC1 +NS(=O)(=O)c1ccc(N2C(=O)CSC2c2cccc(Br)c2)cc1 +COC1CN(c2cc(C3CCN(C4COC4)CC3)cc(-c3cnc(N)c(C(F)(F)F)c3)n2)C1 +CCOCc1nc2c(N)nc3ccccc3c2n1CC(C)(C)OCCNC(C)=O +O=C(c1nc2ccccc2[nH]1)C1CC(Oc2ncccc2C2CCOCC2)C1 +CC1(C(=O)N2CCC(c3ccccc3)CC2)CCCC2(C)c3ccccc3CCC12 +Fc1ccc(C2Cc3[nH]nc(-c4nnn[nH]4)c3C2)cc1F +O=C(NC1CC2CCC(C1)N2Cc1ccc2cc(F)ccc2c1)N1CCCN(Cc2c(Cl)cccc2Cl)CC1 +COCCOc1nc(NS(=O)(=O)NCc2ccccc2)c(Oc2ccccc2OC)c(OCCOc2ncc(Br)cn2)n1 +CS(=O)(=O)NC(=O)c1cc(Cl)c(OCC23CC4(F)CC(F)(CC(F)(C4)C2)C3)cc1F +CC1OC(n2cnc3c(N)nc(OCC4CC45CC5)nc32)C(O)C1Cl +COc1ccccc1C=CC(=O)NC1CCC(CCN2CCc3ccc(OS(C)(=O)=O)cc3CC2)CC1 +CCC(NC(=O)C(CS)C(C)c1ccccc1)C(=O)O +CC(C)(O)C(=O)N(CCN1C2CCC1CC(c1cccc(C(N)=O)c1)C2)Cc1c(F)cccc1F 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+CC1CN(C(=O)c2cn3c4c(cccc24)OCC3C2CCCCC2)CC(C)N1CCO +COc1ccc(N2CCCC2=O)cc1COc1ccc(-c2nc3cc(C(=O)O)ccc3n2C2CCCCC2)c(F)c1 +NC(=O)c1cc(N2CCNCC2C(N)=O)nc(-c2ccc(Oc3ccc(F)cc3)cc2)n1 +CCc1ncnc(-c2cc(F)c(C(=O)N3CCn4cnnc4C3)c(F)c2)c1C#Cc1ccc(N)nc1 +CC(C)c1ccccc1OCCN1CCC(N(CC2CC2)S(=O)(=O)c2cccc(F)c2)CC1 +CNC(=O)c1c(N(Cc2ccc(F)c(C(F)(F)F)c2)S(=O)(=O)c2ccccc2)sc2ccccc12 +Cc1cc(C)c(-c2csc(NC(=O)c3ccc(C#N)cc3)n2)c(C)c1 +O=C(Nc1ccc(CCC2CCCCN2)cc1)c1cnc(Cl)cn1 +CCCCc1nnc(SCC2CCCCC2)n1Cc1ccc(-c2ccccc2-c2nn[nH]n2)cc1 +COc1cc(C=C2CCCN3CCC(c4cc(F)c(F)c(F)c4)ON=C23)ccc1-n1cnc(C)c1 +CC1CCN(c2nccnc2OC2CN(c3ccc4ccccc4n3)C2)CC1 +CCC(C)C(NC(=O)c1cccc(Cn2ccnc2)c1)C(=O)O +CN1Cc2c(-c3ccc(C(=O)O)cc3)[nH]c3nccc(c23)-c2cc(F)ccc21 +O=C1c2ccc(O)cc2C23CCCCC2C1N(CCF)CC3 +O=C(O)CCCOc1ccccc1-c1cc2ccc(C(=O)NC(c3ccccc3)c3ccccc3)cc2o1 +N#CC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1c(F)c(F)c(F)c(F)c1F +O=C(Cc1c[nH]c2ccccc12)NCCCCCCCNc1c2c(nc3cc(Cl)ccc13)CCCC2 +CC(Nc1ccc(F)c(F)c1)c1cc(C(=O)N(C)C)cn2c(=O)cc(N3CCOCC3)nc12 +CC(=O)NC(c1cccc([N+](=O)[O-])c1)c1ccc2cccnc2c1O +CC(O)(COc1ccccc1)C(=O)N1CCc2c(C#N)cccc21 +N#Cc1nc(-c2ccnc(Nc3ccc(CN4CCOCC4)nc3)n2)ccc1N1CCC2(COC2)C1 +c1ccc(CCN2CCC3(N4CCCC4)CC(c4ccccc4)C2C(c2ccccc2)C3)cc1 +Cc1ccn(-c2ccc(C(=O)N3Cc4cccnc4Nc4ccccc43)c(C(F)(F)F)c2)n1 +CCCn1cc(-c2cn3ncc(C(N)=O)c(NC4CN(c5ncc(C#N)cn5)CC4C)c3n2)cn1 +O=S(=O)(Nc1ccccc1)c1ccc2c(c1)CCN2c1cccc(CCCC2CCCC2)c1 +CN(C)S(=O)(=O)N1CCN(c2ccc(CN(CC(F)(F)F)S(=O)(=O)Cc3ccccc3)c(F)c2)CC1 +COc1ccc2[nH]nc(C(=O)NCC3CCN(Cc4ccc(C(F)(F)F)cc4)CC3)c2c1 +CC1CN(c2ccc(NC=C3C(=O)NC(=O)c4ccc(I)cc43)cc2)CC(C)N1 +CCOc1ccc(-c2c(Cl)ncn2-c2ccc(S(N)(=O)=O)cc2)cc1F +O=C(Nc1ccc(Cl)cc1)c1cc(Cl)ccc1NC(=O)c1scc(Cn2ccnc2)c1Cl +CCCC(=O)Nc1cccc(-c2nc(Nc3ccc4[nH]ncc4c3)c3cc(OCCOC)c(OC)cc3n2)c1 +CCCCc1cc2c(c(C(F)(F)F)c1)C(=O)N1CCNCC21 +NC(=NC(=O)c1nc(Cl)c(N)nc1N)NCCCCc1ccc(S(=O)(=O)O)cc1 +NCCCCN(Cc1nc2ccccc2s1)C1CCCc2cccnc21 +Nc1ncc(-c2cc(C3C4CN(C5COC5)CC43)n(C3CCC3)n2)cc1OC(F)(F)F +CCOC(=O)c1nn(C(=O)c2cccc(C)c2)c2ccc(NC(=O)C3CC3)cc12 +CC(O)(CS(=O)(=O)c1ccc(NC(=O)CCl)cc1)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +COC1CCC2(CC1)Cc1ccc(-c3ccc4[nH]cc(C)c4c3)cc1C21N=C(C)C(N)=N1 +CNc1ccc(C=Cc2cccc(C=Cc3ccc(NC)c(O)c3)n2)cc1O +N#Cc1c(-c2ccc(C(F)(F)F)cc2)cc(NCCN2CCCCC2)n2c1nc1ccccc12 +CNC(=O)c1ccccc1Nc1nc(Nc2ccc(CN)cc2)n2ccnc2n1 +CCNC(=S)Nc1cc(-n2cnc(CN3CCCC3)c2)ncn1 +COc1ccc(NC(=O)N2CCN(c3ccc(C)cc3C)CC2)cc1N1CCN(C)CC1 +COc1ccc(N2CCOCC2)cc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +COc1cc(C=Cc2nc3n(n2)CCCC3c2ccc(C(F)(F)F)cc2)ccc1-n1cnc(C)c1 +Cc1c[nH]c2c(Nc3nc(NC4CCCCC4N)cc4cc[nH]c(=O)c34)cccc12 +CC(Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1 +NS(=O)(=O)c1ccc(NC(=O)C=Cc2ccccc2OC(F)F)cc1 +CCN(CC)C(=O)c1ccc(-c2c3ccc(=[N+](C)C)cc-3[se]c3cc4c(cc23)C(C)(C)CCN4C)s1 +COCCOc1ccc(-c2c(C)nc3c(N4CCOCC4)nccn23)cn1 +CN(CCCCCCCCN1C(=O)c2ccccc2C1=O)Cc1ccccc1 +Cc1ccccc1-n1ncc(-c2nc(-c3cc(F)ccc3F)no2)c1-c1ccccc1 +O=C(O)C1Nc2cc(Cl)cc(Cl)c2S(=O)(=O)N1Cc1ccccc1 +CCCCc1nc2c(C)ccnc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +O=C1c2ccccc2C2C(C(=O)O)C(C(=O)O)C2c2ccc(-c3ccc(Cl)cc3)cc21 +Clc1cccc(-c2cnc3ccc(N4CCC(N5CCCCC5)CC4)nn23)c1 +O=[N+]([O-])c1cccc2c1CN(c1ncnc3c1ncn3C1OC(CO)C(O)C1O)CC2 +CCCC1(C)SC(NC2C(C)(C)C2(C)C)=NC1=O +CNC(=O)c1sc2ncnc(N3CCC(COCCN4CCCC4)CC3)c2c1-c1ccccc1 +O=c1[nH]nc2c3c([nH]c4cccc1c43)CNC2 +Cc1ccc(C(=O)NC2CC2)cc1-c1ccn2c(C3CCOCC3)nnc2c1 +Oc1ccc(-c2cc(-c3ccccc3Cl)nc3c2oc2ccccc23)cc1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NS(=O)(=O)c1ccccc1 +N=C(N)Nc1ccc(C(=O)Nc2cccc(SC(CC(=O)O)c3cccnc3)c2)cc1 +O=C(Cn1c(=O)n(-c2ccccn2)c2ccccc21)Nc1ccc2c(c1)CC1(C2)NC(=O)NC1=O +O=C(CCN1CCCCC1CCO)Nc1ccc2c(=O)c3cc(NC(=O)CCN4CCCCC4CCO)ccc3[nH]c2c1 +CCN1CCN(Cc2ccc(C(=O)Nc3ccc(C)c(-n4cc(-c5cccnc5)cn4)c3)cc2)CC1 +CCc1n(Cc2cc3ccccc3o2)cc[n+]1CC(=O)c1ccc(OC)cc1 +COc1cc2c(Oc3ccc(NC(=O)NN=Cc4ccc(C(F)(F)F)cc4)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 +CC(Sc1cc(-c2ccc(C(=O)N3CCC(N4CCCC4)CC3)c(F)c2)cnc1N)c1c(Cl)ccc(F)c1Cl +CC(C)(C#N)CCOc1cc(Cl)cc(Cl)c1-c1nc(N)nc2c1CN(C(=O)NC1CCC1)C2 +COCCOc1cccc(-n2nc(NC(=O)C3CNC(=O)C3)cc2-c2cccc(COC(C)C(F)(F)F)c2)c1F +Nc1nnc(-c2ccc3[nH]cc(-c4nccc(OCC(F)(F)F)n4)c3c2)o1 +COc1cc2nncc(-c3cnc(N4CCC(C(C)(C)O)CC4)c(C)c3)c2cc1OC1CC1 +CCCC(O)c1cnc(N2CCn3c(nc4cc(CO)c(S(C)(=O)=O)cc43)C2C(C)C)nc1C(F)(F)F +CC(N)C(=O)N1CCCN(CCCOc2ccc(-c3noc(C4CC4)n3)c(F)c2)CC1 +COC(=O)c1ccc2c3c(cc(N)c2c1)N(C(=O)c1cc2cc(OCCN(C)C)ccc2[nH]1)CC3CCl +CN1CCN(c2cnc3cc(C(F)(F)F)cc(NCc4cccc(C(N)=O)c4)c3c2)CC1 +CC(=O)N(Cc1ccccc1Cl)CC(Cc1c[nH]c2ccccc12)NC(=O)CN1CCN(c2ccccc2)CC1 +CC(C)c1nc(C(=O)NCC2C3CN(CC(C)(C)F)CC23)c2ccccn12 +CC(C)Oc1ccc2[nH]nc(-c3cc(N4CCC(O)(C(F)(F)F)CC4)ncn3)c2c1 +Cc1cccc(-c2nnc(SCC(=O)NC3CCCCC3)n2Cc2ccccc2)c1 +O=C(O)C1OC(Oc2c(-c3ccc(O)c(O)c3)oc3cc(O)cc(O)c3c2=O)C(O)C(O)C1O +CCCCCCCCC=CCCCCCCCC(=O)NC(COP(=O)(O)O)Cc1ccc(OCCC(C)C)cc1 +CCCCCCCCCCOC1=C(C(=O)O)C(c2ccc3c(c2)OCO3)Oc2ccc(OC(C)C)cc21 +O=C(NCCCCc1ccc(C(F)(F)F)cc1)c1ccccc1CNCCc1ccc(O)cc1 +CN(C(=O)CNc1ccc(C(F)(F)F)cc1)C(CN1CCC(O)C1)c1ccccc1 +O=C(Nc1cccc2cccnc12)c1ccc(N2C(=O)C3C4CCC(C4)C3C2=O)cc1 +CCCCN(CCCC)C(=O)CN1CC(c2ccc3c(c2)OCO3)C(C(=O)O)C1c1ccc(C)cc1 +CCN(CC)C(C)(C)CNc1cc(-c2ccccc2)c(-c2ccccc2)nn1 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+O=c1cc(-c2nc3ccccc3n2C2CC3CCCC(C2)N3C2CC3CCCCC(C3)C2)[nH]c(=O)[nH]1 +Cc1cc(O)c(-c2ccc(C(C)CS(N)(=O)=O)cc2)c2c1[nH]c(=O)c1sccc12 +O=C1c2ccccc2C(=O)c2c(NCCCN(CCCl)CCCl)ccc(NCCCN(CCCl)CCCl)c21 +COC(=O)c1c(C)[nH]c(C)c1C(=O)c1ccccc1CCc1ccccc1 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccc(C#N)nc3)n2)CC1 +CC(CCCc1cccnc1)NC(=O)C=CC=C(c1cccc(F)c1)c1cccc(F)c1 +CCN(CC1CCN(Cc2ccccc2)CC1)C(=O)c1cccc2ccccc12 +COC(=O)C1=C2C=CC(C)C=C2c2nc(-c3ccccc3)nn2C1 +CNC(C(=O)NC(C(=O)N(C)C(C=C(C)C(=O)O)C(C)C)C(C)(C)O)C(C)(C)c1ccccc1 +CC(Cc1cccc(CNCCc2c(Cl)cccc2Cl)c1)NCC(O)c1ccc(O)c2[nH]c(=O)sc12 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CC(Cc1ccccc1)C(=O)NC(CO)Cc1ccccc1 +COc1nc2[nH]c(=O)[nH]c2nc1NS(=O)(=O)c1cccc(Cl)c1Cl +O=C(Nc1ccc(F)cc1F)Nc1cnc2ccc(Cl)cc2c1-c1ccccc1 +CCCCC(N)C(=O)Nc1cc(C(=O)NC(Cc2c[nH]c3ccccc23)C(=O)OCc2ccccc2)ccc1N +O=C(Nc1cccnc1)C(=O)c1cc(Cc2ccc(Cl)cc2)n2ccccc12 +CSc1ccc(-c2c(C)n(Cc3c(F)cccc3F)c(=O)n(CCN(C)CCc3ccccn3)c2=O)cc1 +N#Cc1ccc(-c2cn(-c3ccc(C(=O)O)cc3)cc2C#N)cc1 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+COc1ccc(COc2ccc(C(CC(=O)O)c3ccc(F)cc3)cc2)cc1 +C(=Cc1ccccc1)CN1CCC(c2ccc(Oc3ccccc3)cc2)CC1 +COc1ccc(OC)c(CCOc2nc(Nc3ccc(C(=O)NC4CCN(C)CC4)cc3OC)ncc2C(F)(F)F)c1 +N#Cc1cccc(-c2ccc(N(C(=O)Nc3cc(Cl)cc(Cl)c3)C3CCN(C4CCCC4)CC3)cc2)c1 +CCOc1cc(C#N)cc(-c2ccc3ccc(C)nc3c2)c1 +O=C(NCC1CNC1)c1ccc(O)c2[nH]c(-c3cccs3)nc12 +Cc1ccccc1C=CC(=O)c1ccc([N+](=O)[O-])o1 +Cc1cc(Cl)ccc1C1c2c(nn(CC3CCCN3C(=O)N(C)C)c2C(C)C)C(=O)N1c1cc(Cl)ccc1C +Cc1cc2c(cc1C(C)c1ccc(C(=O)O)cc1)C(C)(C)CCC2(C)C +COc1ccc(CCCCCCCCOc2ccc(C[S+]([O-])Cc3ccc(C(=O)O)cc3)nc2C=CC(=O)O)cc1 +COc1nc(N(C)C)ncc1-c1cc2c(n1C(C)C)C(c1ccc(C#N)cc1)N(c1c(F)c(C)nn1C)C2=O +COc1cccc(OC)c1C1CC(F)C(=O)N1Cc1ccc2oc3ccccc3c2c1 +O=C(Nc1cc[nH]c(=O)c1)c1ccc(Cl)cc1Oc1ccc(F)cc1 +COc1ccc(-c2n[nH]c3ccc(-c4n[nH]c(CN(C)C)n4)cc23)cc1 +CCN(CCCNC1=CC(=O)C(NCCCCCCNC(=O)CCCCC2CCSS2)=CC1=O)Cc1ccccc1OC +COc1ccc2c(c1)C13CCCCC1C(C2)N(C)CC3 +O=C(NCc1ccccc1)c1cccc(NCc2[nH]nc(-c3ccncc3)c2-c2ccccc2)c1 +CC(=O)NC(Cc1cc(F)cc(F)c1)C(O)CNC1(c2cccc(-n3cccn3)c2)CCCOC1 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+O=C1CC(CN2CCC(C(=O)c3ccc(F)cc3)CC2)Cc2nc(N3CCCC3)sc21 +COc1cnc(OCCOc2ncnc(NS(=O)(=O)c3ccc(C(C)(C)C)cc3)c2-c2ccc(C)cc2)nc1 +Cc1c(C)c2c(c(Cn3cc(-c4ccc(O)c(O)c4)nn3)c1O)CCC(C)(C)O2 +COc1ccc(-c2nc(N)sc2-c2cc(OC)c(OC)c(OC)c2)cc1 +COCCN1CCN(Cc2ccc3oc4cccc5c(=O)[nH]nc(c3c2)c45)CC1 +c1ccc(-c2csc3[nH]nc(N4C5CCC4CC(COCCN4CCCC4)C5)c23)cc1 +N#Cc1cccc(NC(=O)NCCCN2CCC(Cc3ccc(F)cc3)C2)c1 +O=C(Nc1cccc2c1CC(O)C2)NC1CCC(c2ccccc2F)C1 +CN(C)C(=O)c1sc2ncnc(N3C4CCC3CC(NC3CCC3)C4)c2c1-c1ccccc1 +O=C(Cc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NCC(c1ccc(F)cc1Cl)N1CCC(N2CCCCC2)CC1 +CCCNC(=O)N1C(C#N)C(c2ccc(-c3cccc(OC)c3)cc2)C1CO +COc1cccc(C(c2c(C)[nH]n(-c3ccccc3)c2=O)c2c(C)[nH]n(-c3ccccc3)c2=O)c1OC +N#Cc1ccc(-n2cc(C(=O)Nc3ccc(C4CNCCO4)cc3F)cn2)c(F)c1 +Cc1cc(Cl)ccc1N1CCN(C(=O)N2CCOCC2)CC1 +COC(=O)C=C(C)c1ccc(C(=O)N=c2[nH]c3cc(N(C)C(=O)c4ccccc4)ccc3n2CCC(N)=O)s1 +CC(C=O)Cc1cc(C(=O)c2ccccc2)ccc1OC(=O)C(C)(C)C +CCCC1(CC(=O)O)OCCc2c1[nH]c1c(C)c(OCCc3ccncc3)cc(C#N)c21 +CC1CN(c2cc(Nc3cc(C(C)C)[nH]n3)nc(NCc3cc(C(C)C)no3)n2)CCN1 +CN1CCN(c2ccc(C(=O)Nc3n[nH]c4ccc(Cc5cccc(F)c5)cc34)c(NC3CCOCC3)c2)CC1 +C=C(C)C1CCC2(C(N)=O)CCC3(C)C(CCC4C5(C)CCC(=O)C(C)(C)C5CCC43C)C12 +CC1(C)OC(=O)N(C2CCC(n3c(=O)[nH]c4cc(C#N)cnc43)CC2)C1c1ccccc1 +CCOC(=O)Nc1nc(Cc2c(Cl)cccc2Cl)nc(Nc2ccc(C#N)cc2)n1 +COc1cccc(NC(=O)Cc2ccc(Nc3ncnc4cc(OC)c(OC)cc34)cc2)c1 +CCOC(=O)CCCNC(=O)C1=NOC(C(O)(C(F)(F)F)C(F)(F)F)C1 +CC1OCCC1N(NC(=O)OC(C)(C)C)c1nc(C#N)ncc1Br +Cc1cc(C)n(-c2nc(NCC(F)(F)F)cc(-n3cccn3)n2)n1 +Cc1ccccc1NC(=O)CSc1nnc(-c2ccccc2)[nH]1 +CCOC(=O)C(C)Sc1nc2cc(-n3nc(C)n(C(F)F)c3=O)c(F)cc2s1 +Cn1ncc(Cl)c1-c1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1OCCN1CCCC1 +O=C(CC(CS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)NC1CCCc2cc(CN3CCCCC3)ccc21 +CC1CN(Cc2c[nH]nc2-c2c[nH]c(C(N)=O)c2)CCN1c1ccc(C(F)(F)F)cn1 +CC(C)C(N)C(=O)SCCOP(=O)(COCCn1cnc2c(N)ncnc21)OCCSC(=O)C(N)C(C)C +Nc1c(C(=O)c2ccccc2)cc[n+]([O-])c1-c1ccccc1 +CC1CCC(COc2nc(C(F)(F)F)ccc2CNC(=O)C(C)c2ccc(NS(C)(=O)=O)c(F)c2)CC1 +CCCCN1CCC(N(Cc2ccccc2)C(=O)Nc2cccc(C(F)(F)F)c2F)CC1 +NC1(C(=O)N2CCCC2c2ccccc2)CCN(c2ncnc3[nH]ccc23)CC1 +CN(C)CCOc1ccc(-c2oc3ncnc(NCC4CCCO4)c3c2-c2ccccc2)cc1 +CC12CN(c3ncccn3)CC(C)(O1)C1C(=O)N(c3ccc(C#N)c(C(F)(F)F)c3)C(=O)C12 +CNc1ncc(-n2nc3c(c2C(C)C)C(c2ccc(Cl)cc2)N(c2c[nH]c(=O)c(Cl)c2)C3=O)c(OC)n1 +CCCOc1ccnc2[nH]cc(-c3ccnc(N)n3)c12 +O=C(Cn1nc(C(F)(F)F)c2c1CCCC2)Nc1sc2c(c1CO)CCCC2 +COc1cc2c(c(OC)c1OC)-c1ccc(=O)c(OC)cc1C(NC(=O)C(F)(F)F)CC2 +CCc1ccc(CN2CCC3(CCN(C(=O)CNC(C)=O)CC3)Oc3ccccc32)cc1 +CC(C)c1ccccc1OCCN1CCC(NC(=O)c2ccc(F)cc2)CC1 +O=c1c2ccc3c(=O)n(CCN=C=S)c(=O)c4ccc(c(=O)n1CCN=C=S)c2c34 +O=C(c1ccccc1)c1ccc2c(c1)sc(=O)n2CCN1CCCC1 +CCN(CC#N)C(=O)C1CC(C(=O)N2CCCC2)C(C)N1 +CNC(=O)Cn1cc(-c2cnc(N)c3c(-c4ccc(Oc5ccccc5)cc4)csc23)cn1 +CC(C)OCCN1CC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)=C(O)C1=O +O=C(Nc1cccc(-c2cnc3c(NC(=O)c4ccc(F)c(Cl)c4)nccn23)c1)c1ccc(F)c(Cl)c1 +CC(CO)NC(=O)c1ccc(OCc2conc2-c2ccc(F)cc2)nc1 +O=C(CCCCCN1CCCCCC1)n1c2ccccc2c2ccccc21 +CC(=O)Nc1cccc(OCC(=O)NCC(O)CN2CCc3ccccc3C2)c1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCC3(CCc4ccccc43)CC1)C(NC(=O)C(N)Cc1c[nH]cn1)C2 +Nc1ncnc2c1C(=O)N(c1ccc(-c3cccc(Cl)c3Cl)cc1)CCO2 +O=C1N(c2ccc(F)cc2)CCc2nc(COc3cccc(F)c3)cn21 +CCC1CN(c2cccc(C(F)(F)F)c2)C(=O)C1c1cccc(F)c1 +Clc1cccc(N2CCN(CCCCc3cn(-c4ccc5[nH]ccc5c4)nn3)CC2)c1Cl +CCCC(NC(=O)C(Cc1c(Br)[nH]c2ccccc12)NC(=O)C(CC(C)C)NC(=O)N1C(C)CCCC1C)C(=O)O +COc1ccccc1C(=O)c1c[nH]c2ncc(-c3cnn(C4CCNCC4)c3)cc12 +CC1=CC(C(=O)N2CCC3(CC2)Cc2cn(C(C)(C)C)nc2C(=O)N3)=CC2C=NNC12 +CC12C=CC(=O)NC1CCC1C2CCC2(C)C(C(=O)Nc3cccc(Br)c3)CCC12 +CCOC(=O)c1c(-c2cccc(C(C)=O)c2)[nH]c2cc(OC)ccc2c1=O +CS(=O)(=O)c1ccc(-n2nc(C(F)(F)F)c(C#N)c2SC2CCCCC2)nc1 +Cc1cc2oc(=O)c(Cc3cccc4ccccc34)c(O)c2cc1C +N#Cc1ccc(Oc2ccc(S(=O)(=O)Nc3nccs3)cc2C#N)cc1Cl +O=C(CCCCc1ccc(O)cc1)NNCc1ccc(O)c(O)c1O +O=C(Nc1ccc(Cl)c(Cl)c1)Nc1ccc(Oc2ccnc(-c3ncc(C(F)(F)F)[nH]3)c2)cc1Cl +Cc1cccc(Cl)c1C(=O)N1CC2CN(CCC(NC(=O)C3CCCC3)c3ccccc3)CC2C1 +Cn1nc(-c2ccc(F)cc2)c2c1CCN(C(=O)CC(N)Cc1cc(F)ccc1F)C2 +COC(=O)C1(C)CCCC2(C)c3cc(OC)ccc3C(=O)CC12 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+O=C(Nc1ccc([N+](=O)[O-])cc1O)Nc1ccc(Br)cc1Br +C=CC(=O)Nc1ccccc1Nc1nc(Nc2ccc(N3CCN(C)CC3)cc2)ncc1Cl +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCCCNC(C)=O +O=C(Nc1ccc(C(F)(F)F)cc1)N1CCN(c2ncc(C(O)CO)cc2Cl)CC1 +COC(=O)CCN1C(=O)c2ccccc2NC1c1ccc(Cl)cc1 +CC(C)Oc1ccc(-c2nccnc2C2CN(c3ccc4ccccc4n3)C2)cc1 +COc1cc(-c2ccc(C)cc2)ccc1-c1nccc2cc(S(=O)(=O)Nc3ccncn3)ccc12 +Clc1ccc(Sc2oc(C3CCOCC3)nc2-c2ccc(N3CCNCC3)nc2)cc1 +O=C(c1cccc(-c2ccco2)c1)N1CCCC(F)(C(=O)Nc2ccc(Cl)cc2)C1 +C=CC(=O)NCCCn1c(-c2nc(-c3cnn(C4CCN(C)CC4)c3)cnc2N)nc2ccccc21 +Cn1nccc1-c1cc(NC(=O)Nc2cccc(F)c2)ccc1OCCN1CCCCC1 +Cc1ccc(NC(=O)c2ccc3ccccc3c2)c(Cl)c1 +COc1ccc(C=CCN2CCN(C(=O)CCCCC(c3ccccc3)c3ccccc3)CC2)cc1 +CC1CCCN1CCCOc1ccc(N2CCN(C(=O)c3ccc(F)cc3F)CC2=O)cc1 +Cc1cc(-c2sc(Cc3ccc(Cl)cc3)nc2C)ccc1C(N)=O +C#CC1CCC(C#N)N1C(=O)CNC12CC3CC(CC(O)(C3)C1)C2 +COc1cc(-c2cc(=O)c3c(OC)c(OC)c(OC)cc3o2)cc(OC)c1OC +Cn1nnc(Cc2ccc3c(c2)c(C2CCN(CCN4CCNC4=O)CC2)cn3-c2ccc(F)cc2)n1 +O=C(C1CC(N2CCN(c3nnnn3-c3ccccc3)CC2)CN1)N1CCSC1 +NCCn1nc2c3c(c(NCCNCCO)ccc31)C(=O)c1c(O)ccc(O)c1-2 +FC(F)(F)c1nncn1C1CCN(Cc2cc3nc(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3s2)CC1 +CCC1C=CC(O)C(C)OC(=O)C(C)=CC2C(=O)NC3=CC(=O)c4c(cc(C)c(O)c4C(=O)CC1)C32O +CCCCCC(O)c1ccc(N2C(=O)CCC2CCCc2ccc(C(=O)O)s2)cc1 +CCCCCc1ccc(C(=O)N(CCN(CCCC)CCCC)Cc2ccc(NCc3ccccc3)cc2)cc1 +O=C(c1ccc(-c2ccccc2)[nH]1)N1N=C(c2cccnc2)CC1c1ccccc1O +Clc1ccc(Oc2ccc3c(NCCCNCc4ccco4)ccnc3c2)cc1 +C=CCN(CC=C)Cc1c(C(F)(F)F)nc2n(-c3c(C)cc(C)cc3C)c3ccccc3n12 +CN1CCN(c2ccc3[nH]c(-c4c(N)c5ccccc5[nH]c4=O)nc3c2)CC1 +CCc1cc(C2SCC(=O)N2CCCN(C)CCOc2ccc3c(c2)OCO3)cc(CC)c1O +O=C1CCCN1c1cc(Cc2n[nH]c(=O)c3c2CCCC3)ccc1F +N=C(N)NCCCn1cc(-c2ccc3ccc4ccc(-c5cn(CCCNC(=N)N)nn5)nc4c3n2)nn1 +O=C1CN2Cc3cc(OCCCc4nnnn4C4CCCCC4)ccc3N=C2N1 +CC(O)CCOc1cc2ncccc2cc1NC(=O)c1csc2cncnc12 +NC(=O)c1ccc2[nH]c(-c3ccc(Oc4ccc(Cl)c(O)c4)cc3)nc2c1 +COc1c(C(C)(C)C)cc(CN2CCN(CCCCCC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1C(C)(C)C +CCC1COc2cccc3c(=O)c(C(=O)NC4CCCCC4)cn1c23 +COC(=O)C(Cc1cccc(C(=N)N)c1)C(C)NC(=O)c1ccc(-c2ncc[nH]2)cc1 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+CCCCc1ncc(C=C2C(=O)N(CCCC)C(=O)N2CCCC)n1Cc1ccc(-c2ccccc2C(=O)OC)cc1 +O=C(CSc1nnc(-c2ccccc2)c(-c2ccccc2)n1)c1c[nH]c2ccccc12 +CCCCN(CC)Cc1c(CC)nc2cc(C=CC(=O)NO)ccn12 +Cc1c(CC(=O)OC(C)C)cc(-c2ccc(S(C)(=O)=O)cc2)n1-c1ccc(F)c(F)c1 +CC(=O)CC1Cc2sccc2C2(CCN(Cc3ccccc3)CC2)O1 +COc1cc(CN(CC2CC2)C(CC(=O)O)c2ccc3c(c2)CCO3)ccc1OCCn1c(=O)ccn(C)c1=O +COc1cc(CN=C(S)NC(c2ccccc2)c2ccccc2)ccc1O +COc1ccc(C2C(c3ccc(C)cc3)CC3CCC2N3C)cc1 +N#Cc1cc(CN2C(=O)N(Cc3ccccc3)C(CCc3ccccc3)C(O)C2Cc2ccccc2)ccc1F +Cc1ccc(C2CCC(N3CC(NC(=O)CNc4nn(C)c5ccc(C(F)(F)F)cc45)C3)CC2)cn1 +COc1ccc2cnc(Nc3ccc(N4CCNCC4)cc3)nc2c1C1CCCC1 +COc1cc(Cl)ccc1OCC1CN(Cc2ccc(Br)cc2)CCCO1 +CC12CCC(=O)C=C1CCC1C2C(O)CC2(C)C1CCC2(OC(=O)c1ccco1)C(=O)CSc1nc2ncccc2s1 +Cn1cc(-c2cc3c(-c4cccc(N5CCC(CN)CC5)n4)n[nH]c3cn2)cn1 +COc1ccc(C(=O)Nc2nc(-c3ccccc3)cs2)cc1 +CC1=NC(C)=C(C(=O)OCCCN2C(=O)c3ccccc3S2(=O)=O)C(c2ccccc2Cl)C1=C(O)OCC1CCCO1 +C=C1C(C=CC(=O)OC)=C(C(=O)O)N2C(=O)C(=Cc3ccccn3)C2S1(=O)=O +O=C(O)c1c(CCCOc2ccc(Cl)c3ccccc23)c2cccc3c2n1CCS3 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+O=S(=O)(NCCCCN1CCN(c2ccc(Cl)cc2)CC1)c1ccc2cccnc2c1 +Cc1ccc(OCc2ccc(F)cc2)c(-c2ccc(C)n2-c2ccc(F)c(C(=O)O)c2)c1 +O=C(O)CC1(CCc2ccccc2)C2CC3CC(C2)CC1C3 +CCC1CCCC(C2(Cc3nc(CN4CCCC4)no3)CC2)N1S(=O)(=O)c1ccc(Cl)cc1 +Cc1noc(C)c1CC(=O)NCc1ccc(F)c(Cl)c1F +C=CCCCCC(NC(=O)c1cccc(O)c1OCCC=C)C(O)CN(CC(C)C)S(=O)(=O)c1ccc(OC)cc1 +CN(N=Cc1ccccc1C(=O)O)c1nc(-c2ccccc2Cl)cs1 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC=O)c1=O)C(=O)C(F)(F)F +CC(O)CNc1ncnc2oc(-c3ccccc3)c(-c3ccccc3)c12 +CC(C(=O)N1CCOCC1)N1CCC(NS(=O)(=O)C2=Nc3ccc(Cl)cc3C2)C1=O +Cc1cccc(C)c1-c1cccc(COc2ccc(CCC(=O)O)c(F)c2)c1 +CCCCN(NC(=O)C(CCC)N1CCC(CCCN=C(N)N)(NCCCC2CCCCC2)C1=O)C(=O)OCC +Cc1c(N(Cc2ccc(OC(F)(F)F)cc2)S(=O)(=O)c2ccc(C(=O)NC#N)cc2)ncc2ccccc12 +O=C(Nc1ccccc1)N1CCN(Cc2ccc(Br)c(Br)c2)CC1 +Cn1c(=O)ccc2cc(NS(=O)(=O)c3ccc(C#N)c(Cl)c3)ccc21 +COC(=O)C1(C)CCCC2(C)c3cc(O)ccc3CCC12 +CCCN(C)C(=O)CCCCCCCC1CC2CC(=O)CCC2(C)C2CCC3(C)C(O)CCC3C12 +CCCN1CCN(CCCOc2cc3ncc(C#N)c(Nc4cc(OC)c(Cl)cc4Cl)c3cc2OC)CC1 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+COc1cc(OC)c(-c2cc3ccccc3[nH]2)cc1C=CC(=O)c1ccc(C(=O)O)cc1 +O=C(NC1CCCCC1CO)c1cccc(C2CCCCC2)n1 +CCOC(=O)c1ccc2c(C(=O)NCc3ccc(F)cc3)c(C(C)C)n(Cc3ccccn3)c2c1 +Cc1cc(Nc2cccc(Cl)c2)n2nc(C(C)(F)F)nc2n1 +CCCc1nc2c(C)ccnc2n1Cc1ccc(-c2cccnc2-c2nn[nH]n2)cc1 +CC(C)C(N)CNc1nc(-c2ccncc2)nc2c(Br)csc12 +CC(Nc1cc2c(-c3cc(Cl)cc(CCC(N)=O)c3)noc2cn1)c1ccccc1 +COC(=O)C(NC(=O)c1c2c(nc3ccccc13)-c1ccccc1CC2)c1ccccc1 +NC(CC(=O)NC1(c2cccc(-c3cncs3)c2)CCS(=O)(=O)CC1)Cc1ccccc1F +CC(c1ccc(C(F)(F)F)cc1)N1CCC(CCC(N)=O)(c2ccc(F)cc2)OC1=O +CC1CC(=O)Nc2cccc(-c3ccc4c(c3)c(C3CC3)nn4C)c2N1 +O=C1OCCc2cc(CCN3CCN(CC(O)c4ccc5c(c4C(F)(F)F)COC5=O)CC3)ccc21 +CS(=O)(=O)c1cc(C(=O)N=C(N)N)c(N)cc1N1CCCC(O)C1 +CN1CCN(c2ccc(Nc3cc(-c4cccc(-n5ccc6cc(C7CC7)ncc6c5=O)c4CO)cn(C)c3=O)nc2)CC1 +O=C(NC1CCN(C(=O)CCc2cccnc2)CC1)C(c1ccccc1)C1CCCCC1 +Cc1cc(NC(=O)CCl)sc1-c1nnc2n1Nc1nc3ccccc3nc1S2 +CC(C)Oc1ccc(S(=O)(=O)N2CCN(c3ccc([N+](=O)[O-])c(OCC(=O)O)c3)CC2)cc1 +Cc1ccc(-c2cc(NC(=O)c3cnn4cccnc34)n(-c3ccc(C4CC4)cc3F)n2)cc1 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+O=c1ccn(CC=CCOC(c2ccccc2)(c2ccccc2)c2ccccc2)c(=O)[nH]1 +NS(=O)(=O)Oc1ccc(-c2ccc(C(=O)c3c(F)ccc(O)c3F)s2)c(F)c1 +O=C1CC(CN2CCN(Cc3ccccc3)CC2)Cc2ccccc21 +COc1cc(C)c(S(=O)(=O)N(C)CCOCC(=O)N2CCN(CC3CCN(C)CC3)CC2)c(C)c1 +CCc1ccc(CC)n1-c1c(C)c(C(=O)NC2CCCCC2)nn1-c1ccc(Cl)c(Cl)c1 +Cn1cncc1C(O)(c1ccc(C#N)cc1)c1cc2cc([N+](=O)[O-])cc(-c3ccccc3F)c2o1 +O=C(NC(=S)Nc1ccc(NC(=O)c2cccs2)cc1)c1ccco1 +Cc1ccc(NC(=O)c2ccc(CN)cc2)cc1Nc1nccc(-c2cccnc2)n1 +O=C(c1cccnc1)N1CCc2nc(-c3cc4cc(F)ccc4[nH]c3=O)[nH]c2C1 +CCCC(=O)N1CCc2c(nc(C)n2C2CC3CCC(C2)N3CCCN(C(=O)Nc2ccc(C)cc2)c2ccccc2)C1 +CN(C(=O)c1cc(-c2cccc(O)c2)sc1-c1cccc(O)c1)c1cccc(O)c1 +Cc1cc(CNc2ccc(Cc3c[nH]c4ncc(Cl)cc34)c(F)n2)ccn1 +Cc1cc(S(=O)(=O)NC(=N)NNc2ccc(S(N)(=O)=O)cc2)c(SCc2cccc(C(F)(F)F)c2)cc1Cl +COc1ccc(-c2cc3ncccc3c(OCC3CCC(=O)NC3)n2)cc1OC +Cc1[nH]sc2ncc3c(=O)n(-c4ccc(Cl)cc4)nc3c12 +Cc1[nH]c2nc(N)nc(O)c2c1Sc1ccc(C(F)(F)F)cc1 +Cc1ccc(C)n2nc(CCc3nc(-c4cccnc4)cn3C)nc12 +Cc1ccc(O)c(Cn2c(NC3CCN(CCC(C)C)CC3)nc3c(C)cccc32)n1 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+CNc1nc2sc3c(NCCN4CCOCC4)ncnc3c2c2c1COC(C)(C)C2 +N#CC1CC(NCC(F)(F)F)CCC1n1cc(C(N)=O)c(Nc2ccc(Cl)cc2)n1 +Cn1c2ccccc2c2cc(CCOc3ncccc3-c3ccc(Cl)cc3)cnc21 +CC(=O)c1ccc(Nc2nc(OCC3CCCCC3)c3[nH]cnc3n2)cc1 +O=c1[nH]c(=O)n(C2COC(CO)O2)cc1C=CI +COC1(c2cc(OCc3ccc4c(ccc(=O)n4C)c3)cc(F)c2C)CCOCC1 +COC1COCCC1NC1CCC(C(=O)N2CCN(c3cc(C(F)(F)F)ccn3)CC2)(C2CCOC2)C1 +CCC(Nc1cccc(CN2CC(C(=O)O)C2)c1)c1ccc(Cl)c(C)c1 +O=C1C2CCCC2N1c1ccc(C#Cc2ccccc2)cn1 +CC(CCC(=O)Nc1ccc(S(N)(=O)=O)cc1Br)C1CCC2C3CCC4CC(O)CCC4(C)C3CCC12C +COCCOCC1(C(=O)Nc2cccc(OC(=O)N(C)C)c2)CCN(c2ncnc3[nH]cc(C)c23)CC1 +CCc1cc(CNC)cc(OCc2ccc3c(C)cc(N)nc3c2)c1 +O=C1C=C(c2cc[n+]([O-])cc2)S(=O)(=O)c2ccccc21 +Nc1ncnc2c1c(-c1cccc3[nH]ccc13)nn2C1CCCC1 +COc1ccc(OC)c(CNC(=O)c2ccc(Oc3ccc(C(C)(C)C)cc3)cc2)c1 +COc1ncccc1-c1cccn2nc(Nc3ccc(C4CCN(CC(=O)N(C)C)CC4)cc3)nc12 +CC(C)N(Cc1cccc2c1OC(C)(C)C=C2)C(=O)c1ccc(-c2ccccc2)cc1 +CCOC(=O)c1cc(N2CCN(C)CC2)nc2ccccc12 +C[N+](C)(CCOc1ccccc1)CC1COC(c2ccccc2)(c2ccccc2)O1 +O=C(Nc1ccccc1CCO)NC1CCN(Cc2ccc3cc(F)ccc3c2)C1 +CCC(O)c1c(F)cncc1-c1cnc2c(c1)CCCN2C(N)=O +CNCc1cn(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)nc1C(F)(F)F +CN(C)C1CCc2c(c3ccccc3n2S(=O)(=O)c2ccc(Br)cc2)C1 +CN=C(S)OCC1OC(n2cnc3c(NC4CCOC4)ncnc32)C(O)C1O +CCCCCCCN1C(=O)NC(c2ccc(Br)cc2)(c2ccc(Br)cc2)C1=O +CCOC(=O)c1cc2c(CC)c3c(nc2cn1)-c1cc2c(c(=O)n1C3)COC(=O)C2(O)CC +CC1CCC(C(=O)N(c2ccc(Oc3ccccc3C(C)(F)F)cc2C(=O)O)C(C)C)CC1 +CCCc1nnc2n1CCc1c(CC)nn(C3CCCC3)c1-2 +CCN(CC)C(=O)c1ccc(N(c2ccccc2)C2CC3CCC(C2)N3C(=O)c2ccc3c(c2)OCO3)cc1 +COc1cc(NC(=O)Nc2cccc3c2C2CCCCN2C3=O)nc2ccccc12 +NC(=O)c1ccc(-c2ccc3c(c2)nn2cc(-c4ccccc4)c(-c4ccc(C5(N)CCC5)cc4)nc32)cc1 +CCNS(=O)(=O)Oc1cc(C(C)(C)C)c(SC2=C(O)OC(CCc3ccccc3)(C(C)C)CC2=O)cc1C +CN(C)CCCN1CCSc2cc(N=C(N)c3cccs3)ccc21 +N#Cc1cc(-c2ccnc(Nc3cncc(-c4cccnc4)c3)c2)ccc1OC1CCOCC1 +COc1cc(-c2nnc3n2CCOC3c2ccc(Cl)c(Cl)c2)ccc1-c1cnc(C)o1 +Cc1ccsc1C(=O)Nc1cccc(Oc2ccnc(-c3cc(C(=O)O)c[nH]3)c2)c1 +O=C(O)c1ccccc1C(=O)N1CCC(N2CCC(Oc3ccc(Cl)c(Cl)c3)CC2)CC1 +COc1cc(-c2ccc(C(=O)N(C)C)cc2)cc(C=O)c1O +COCCNc1cc(Nc2nccc(-c3cnc(N4CCC(F)C4)c(C#N)c3)n2)ccn1 +CCCC1CN(C(=O)c2cc3cc(C#N)ccc3[nH]2)CCN1c1nc(N)c2cc(OC)c(OC)c(F)c2n1 +CC(NC(=O)Nc1ccon1)c1ccc(OC2CCN(c3ccnc(N4CCOCC4)n3)C2)cc1 +CC(Nc1ncc2ncn(-c3cc(C4CC4)[nH]n3)c2n1)c1ccc(F)cn1 +CCCS(=O)(=O)Nc1ccc2c(c1)S(=O)(=O)N=C(c1c(O)c(-c3cccs3)nn(CCC(C)C)c1=O)N2 +Cc1nc2cc(-c3c(C)noc3C)cc(-c3c(C)n[nH]c3C)c2[nH]1 +Cn1cc(S(=O)(=O)NCCOc2ccc3c(c2)C(C2(c4ccc(Cl)cc4)CC(F)(F)C2)NCC3)cn1 +CCCC#Cc1nc(N)c2ncn(C3OC(C(=O)NCC)C(O)C3O)c2n1 +CC(C)(NC(=O)c1ccc2nc(NC3CCC(O)CC3)c3nccn3c2c1)c1ccccc1 +CCCCCCCCCCc1ccc[n+](CC(P(=O)([O-])O)P(=O)(O)O)c1 +CC(C)c1c[nH]c(=O)n(CCCN2CCN(c3ccc(F)cc3OCC(F)(F)F)CC2)c1=O +CCC(CC)ON(CC(O)C(Cc1ccccc1)NC(=O)OC(C)(C)C)S(=O)(=O)c1ccc(OC)cc1 +CCOc1cccc(NC(=O)c2ccc(N3CCCC3)c(C(F)(F)F)c2)c1 +COc1cc2ccccc2cc1C(=O)C(=NC1CCCC1)n1ncc(C#N)c1N +CC(Oc1cc(-c2cccc(S(C)(=O)=O)c2)cnc1N)c1cc(F)ccc1-n1nccn1 +Cc1cccc(C)c1NC(=O)c1ccc(-c2ccsc2)o1 +O=S(=O)(Nc1ncns1)c1ccc2c(-c3ccc(Cl)cc3C3=CCNCC3)cccc2c1 +O=C1NCCn2c(-c3ccc(F)cc3)cc3cccc1c32 +COc1cc(OC)cc(N(CCCN2CCC(C3CC(C)OC(C)C3)C2)c2ccc3ncc(-c4cnn(C)c4)nc3c2)c1 +Cc1cnc(-c2ccc(-c3ccccc3S(=O)(=O)Nc3onc(C)c3C)cc2)o1 +NC(=O)c1c(Nc2ccc(N3CCNCC3)cc2OC(F)(F)F)nc(Cc2c(Cl)cccc2Cl)c2nc[nH]c12 +COc1cccc(-c2ccc3c(c2)CCc2c-3nc3ccc(F)cc3c2C(=O)O)c1 +CN1C2COCC1CC(OC(=O)c1cn(-c3cnccn3)c3ccccc13)C2 +Cc1cn(CCCn2c(=S)[nH]c3sc(Cc4ccccc4)cc3c2=O)cn1 +CCCCCC=CCC1(O)C=C(Cl)C(=O)C1CC(OC(C)=O)C(CCCC(=O)OC)OC(C)=O +CC1CCc2cc(-c3ccnn3C)ccc2N1C(=O)c1ccc(O)cc1O +CC1=C(Sc2cccc(Br)c2)C(COCCO)C(=O)NC1=O +CCOC(=O)c1cn(Cc2cccc(Cl)c2F)c2nc(N3CCN(c4nc5ccccc5o4)CC3)ccc2c1=O +O=C(Cc1cccc2ccccc12)Nc1cn(C2CC(NC(=O)c3ccccn3)C2)cn1 +COc1cc2c(OC3OC4COC(C)(C)OC4C(O)C3O)c3c(c(-c4ccc5c(c4)OCO5)c2cc1OC)C(=O)OC3 +O=C(Nc1nc2cccc(-c3ccc(CNC4CCS(=O)(=O)C4)cc3)n2n1)C1CC1 +N#CC1CCCN1C(=O)CNC1CCC(Nc2ccc(C(F)(F)F)cn2)CC1 +CCOc1ccc(OC)c(C(=O)C=Cc2ccc(O)c(O)c2)c1 +CC1CCc2cc(-c3nc4ccc(Cl)cc4cc3CO)ccc2N1C(=O)c1ccc(O)cc1O +CCOc1ccc(Cl)c(-c2nnc3c(C)nc4ccc(CN5CCOCC5)cc4n23)c1 +Cc1cc(Oc2cncnc2)cc(C(=O)Nc2cc(F)ccn2)n1 +C=CCCC(=O)OC1CCC2(C)C(CCC3(C)C2CCC2C4C(C(=C)C)CCC4(C(=O)O)CCC23C)C1(C)C +Cc1c(C(=O)NN2CCCCC2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +O=C(Cc1nc(-c2ccccc2)cs1)Nc1ccc(CCNCC(O)c2cccnc2)cc1 +C=C1C(=O)OC2CC(C)C3C(OC(C)=O)CC(O)C3(C)C(OC(C)=O)C12 +CN(C)c1ncnc2c1c(I)cn2C1OC(CO)C(O)C1O +CC(C)(C)c1ccc(S(=O)(=O)Nc2cc(SCC(=O)O)c(O)c3ccccc23)cc1 +CN(CC#N)CC1CCC(Nc2c(C(=O)C3CC3)cnc3ccc(-c4cc(F)c(O)c(Cl)c4)cc23)CC1 +CC1CC(C)(C)NC(CCOP(=O)(OCC2OC(n3ccc(=O)[nH]c3=O)CC2O)N(C)CCBr)O1 +CN(C)CCCN1C2=C(C(=O)Nc3ccccc3F)C(=O)CCN2c2ccc(F)cc21 +Cn1c2nc3ccccc3c-2c(NCCc2c[nH]c3ccccc23)c2cc(Cl)ccc21 +CC1(c2ccc(CCC(=O)O)cc2)c2ccc(O)cc2CCN1c1ccc(F)cc1 +FC(F)(F)c1cc(COC2CCC(CN3CCCCC3)C2c2ccccc2)cc(C(F)(F)F)c1 +O=c1ccc(OCCCN2CCC(c3noc4cc(F)ccc34)CC2)nn1-c1cc(Cl)ccc1Cl +COc1ccc(C(=O)C2C(=O)C(=O)N(c3nc4cc(OC)ccc4s3)C2c2ccccc2OCCO)cc1 +O=C(NC1CCCC1Nc1ncc(C(F)(F)F)cc1Br)c1ccccc1-n1nccn1 +CC(NC(=O)C1CC(S(=O)(=O)c2ccccc2C(F)(F)F)CN1c1ccnc(C#N)n1)C(F)(F)F +COc1ccc(-n2nc3c(N4CCC(C(=O)N5CCCCCC5)CC4)nnc(C)c3c2C)cc1 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+CC(C)C1CN(CC2COCCN2)C(=O)N1c1ccn2ncc(-c3ccc(-c4nc[nH]n4)cc3)c2n1 +O=c1c(CN2CCN(Cc3ccccc3)CC2)coc2ccccc12 +CCC(C)c1ccc(N2C(=O)c3ccccc3NC2c2ccc(C(C)C)cc2)cc1 +CC(C)(O)c1ccccc1CCC(SCC1(CC(=O)O)CC1)c1cccc(C2CC2c2ccc3sc(Cl)c(Cl)c3n2)c1 +Cc1cc(O)c(Cl)cc1-c1ccc2ncc(C(=O)C3CC3)c(N3CCC(CN(C)C)CC3)c2c1 +Cc1ccncc1CN1CCc2c(sc3ccc(F)cc23)C1 +CNC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1O2 +CC(=O)c1c(C)c2cnc(NC3CCCCN3c3cccnc3)nc2n(C2CCCC2)c1=O +CS(=O)(=O)Nc1cccc(-c2ncc(-c3ccc(Oc4ccccc4)cc3)c3c(N)n[nH]c23)c1 +CCC(C)C(N)CN(C(=O)C1CC1c1ccsc1)c1ccc(-c2ccccc2)cc1 +CS(=O)(=O)NC(=O)c1cc(C2CC2)c(OCC2(C#N)CCCCC2)cc1F +Cc1cc(Nc2nccc(C(F)(F)F)n2)cc(-c2cccc(N)c2)c1 +CN1CCN(c2nc(NCc3cccs3)c3cc(Cl)ccc3n2)CC1 +COc1ccc(Cl)cc1S(=O)(=O)N(C)c1cc(C(=O)Nc2ccc(C(=O)O)cc2)cc2c1OCCO2 +COCCc1nnc(-c2ccn3c(-c4cccc(NC(=O)NCC(F)(F)F)c4)cnc3c2)s1 +CCc1nc2cc(C=CC(=O)NO)ccc2c(=O)n1CCc1ccc(F)cc1 +CC(=O)N1CCc2c([nH]c3ccc(C)cc23)C1c1c[nH]c2ccccc12 +CNC(=O)COc1ccc2nc(CC(C)C)c(CN)c(-c3ccc(C)cc3)c2c1 +O=C(O)c1cccc(NC(=O)c2[nH]c(C3CC3)nc2CCC23CC4CC(CC(C4)C2)C3)c1 +NCCCCC1C(=O)Nc2ccc(O)cc2C(=O)N1C(C(=O)NCC(=O)O)c1cccnc1 +CCn1c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)cc2ccccc21 +Cc1ccc(C(=O)Nc2nccc3ccccc23)cc1S(=O)(=O)N1CCCCC1 +O=C1NCCc2c1ccc1[nH]cc(CCNCc3ccccc3)c21 +CCn1cnc2c(Nc3ccc(P(C)(C)=O)cc3)nc(C(C)C)nc21 +C#CCN(Cc1ccc2nc(CC#N)nc(O)c2c1)c1ccc(C(=O)NCc2cccc([N+](=O)[O-])c2)cc1 +CCOc1ccc(C(=O)Nc2ccc(C3CNCCO3)cc2F)cn1 +O=C1NC(=O)c2cc(Nc3cccc(O)c3)c(Nc3cccc(O)c3)cc21 +C=Cc1ccc2c(NC(C)c3ccc(NC(=O)c4ccc(Cl)nc4)cc3)nc(N(C)C)nc2c1 +CN(C)C1COc2ccccc2-c2c(C3CCCCC3)c3ccc(C(=O)O)cc3n2C1 +CN(CCc1cc(CCC(=O)O)cc(Cc2cccnc2)c1)S(=O)(=O)c1ccc(Cl)cc1 +CCn1cnc2c(Nc3cccc(Cl)c3)nc(NCCO)nc21 +CC=C1NC(=O)c2csc(n2)CNC(=O)CC(C=CCCSC(=O)CCCCCCC)OC(=O)C(C(C)C)NC1=O +COC1(C#CC(O)(c2ccccc2)c2ccccn2)CN2CCC1CC2 +COCCOCCOc1ccc(S(=O)(=O)N(CC(=O)NN=C2C(=O)Nc3ccccc32)c2ccc(Cl)cc2)cc1 +CC1Cc2c([nH]c3cc(F)c(F)cc23)C2(N1)C(=O)Nc1ccc(Cl)cc12 +O=C(NC1CC2COCC(C1)N2)c1cn(CC(F)(F)F)c2ccc(F)cc12 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+NC1CC(N2Cc3nn4c(C(F)(F)F)ccnc4c3C2)CCC1c1cc(F)c(F)cc1F +Cc1cc(N2CCOCC2)nc(N(CCCNc2ccnc3cc(Cl)ccc23)Cc2ccco2)n1 +O=C(CC(NS(=O)(=O)c1ccc2ccccc2c1)c1ccccc1)NC1CCOc2cc(CNC3CCCCC3)ccc21 +O=C(O)c1ccc(CN(CCC2CC2)C(=O)c2ccc(Oc3ccccc3F)cc2)cc1 +Cc1nn(Cc2cccc3cccnc23)c2cc(CC(=O)O)ccc12 +CC1CCC(NC(=O)C(CC2(C)CCCCC2)NC(=O)c2ccco2)C(=O)CN1C(=O)c1ccccn1 +NS(=O)(=O)c1cccc(CN2CCCC(Nc3ccc4[nH]ncc4c3)C2)c1 +O=C(Nc1ccc(OC2CCN(C(=O)C3CCC3)C2)cc1)N1Cc2ccncc2C1 +Cc1cc(O)c(CN2CCCC2)c2c1C(=O)C(=Cc1ccco1)O2 +COc1ccc(S(=O)(=O)N(CC(C)C)CC(O)C(Cc2ccccc2)NC(=O)c2ccccc2C(F)(F)F)cc1 +CC(C)CCOc1ccc2c(c1)C1OCCCC1C(C1CCCC1)N2 +CC(=O)C1=C(C)N(c2cccc(C(F)(F)F)c2)C(=O)NC1c1ccc(C#N)cc1-c1ccn(C)c(=O)c1 +CC(C)c1cccc(-c2cc(NC(=O)C3CNC(=O)C3)nn2-c2ccccc2)c1 +CCCCCn1c(C)c(C(=O)c2ccc(OCC)c3ccccc23)c2ccccc21 +Nc1cc(C2CCC(CNS(=O)(=O)c3ccccc3[N+](=O)[O-])CC2)nn1-c1cccc(C(F)(F)F)c1 +Clc1ccc(-c2[nH]c3ccccc3c2C=NNC2=NCCN2)cc1 +CCc1nn(Cc2ccc(C(=O)Nc3ccc4ccccc4n3)cc2)c(CC)c1CC(=O)O +COc1ccc(Oc2c(C)[nH]c3cc(S(C)(=O)=O)ccc23)cc1 +O=C(NC(c1ccc(F)cc1)c1ccc(F)cc1)C1CCC(N2CCOCC2)CC1c1ccc(Br)cc1 +CC(Nc1cc(NCCOc2ccc(F)cc2)ncn1)c1ccccc1 +CC(C)(CC(O)(Cc1ccccc1)C(=O)Nc1ccc2c(c1)COC2=O)c1cc(F)ccc1O +O=C(CN1CCN(c2ccc(F)cc2)CC1)Nc1ccc2c(c1)Cc1c-2nc(O)c2ccccc12 +Nc1nc(O)c2nn(-c3cccc(C(=O)NCc4ccccc4Sc4ccccc4CO)c3)nc2n1 +C=C(C)CN1CCC23c4c5ccc(O)c4OC2c2ncc(-c4ccc(Cl)cc4)cc2CC3(O)C1C5 +Cc1ccc(S(=O)(=O)n2c(N)nc3ccccc32)cc1 +CC(C)(O)COc1ccc(C(F)(F)F)cc1C(=O)N=c1sc2ccncc2n1CC1CCC1 +CC(=O)c1cnc2ccc(-c3ccc4nc[nH]c4c3)cc2c1Nc1ccc(OCCN(C)C)nc1 +CCCCN(CC)c1nc(C)nc2c1n(C)c(=O)n2-c1c(C)cc(C)cc1C +Cc1nc(N2CCC(N3CCOCC3)CC2)nc2ccc(NC(=O)C=Cc3ccc(Cl)cc3)cc12 +O=P(O)(O)C(F)(Cc1cncc(-c2cn[nH]c2)c1)P(=O)(O)O +CCOc1ccc(S(=O)(=O)N(CC)CC)cc1-c1nnc2c(n1)c(C)nn2C +O=C(c1ccc(-c2cnc3c(c2)N(Cc2cc(Cl)ccc2C(F)(F)F)CCN3)cc1)N1CCCCC1 +O=C1NCCc2c(-c3ccccc3Cl)[nH]c3cccc1c23 +Cc1cc(C)cc(Nc2nccc(-c3cnn4ncccc34)n2)c1 +CC(C)CC(NC(c1ccc(-c2ncccn2)cc1)C(F)(F)F)C(=O)NCC#N +CCNC(=O)c1ccc2nc(C)c3nnc(-c4ccccc4Cl)n3c2c1 +CCOC(=O)C=CS(=O)(=O)c1ccc(NC(C)=O)cc1 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+CNCC1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)C1 +CCN(CC)C(=O)C1Sc2ccccc2-c2c1c1cccc(OC)c1n2CCF +O=C(C=Cc1ccc(S(=O)(=O)n2ccc3ccncc32)cc1)NO +CN1C(=N)NC(C)(c2sc(-c3cc(-c4nnco4)ncc3F)cc2F)CS1(=O)=O +O=C(O)Cc1cccc(NC(=O)CCC(NC(=O)c2cc(Cl)cc(Cl)c2)C(=O)N2CCC3(CCCC3)CC2)c1 +Cc1cc(OCc2nnc(SC3CCCC3)n2-c2cccnc2)ccc1-c1ccc(S(C)(=O)=O)cc1 +CN1CCN(C(=O)c2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(F)c3)o2)CC1 +O=C(NC1c2ccccc2CC1O)C(OCC=CBr)C(O)C(O)C(OCC=CBr)C(=O)NC1c2ccccc2CC1O +N#CC(C#N)=C1C(=O)Nc2ccc(S(=O)(=O)N3CCCC3COc3ccccc3)cc21 +Cc1cc(Br)ccc1CNCC(NC(=O)CNC(=O)c1cccc(C(F)(F)F)c1N)C(=O)NC(C)(C)C +CC1CN(c2noc(C3CC3)n2)CCN1c1ncc(OCc2ccncc2C#N)cn1 +Cc1ccc(-c2nccnc2C2CN(c3ncc4ccccc4n3)C2)cc1 +O=C(O)C1NC2(CCCCC2)C2(C(=O)Nc3cc(Cl)ccc32)C1c1cccc(Cl)c1F +CCCCCCCNC(=O)Oc1ccc2c(c1)CN(C)C(c1c(Cl)cccc1Cl)N2C +COc1cc(-c2cnc(NC(C)c3ccc(F)cc3)nc2)ccc1-n1cnc(C)c1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OCCc2ccccc2)C1c1[nH]cnc1Cl +Oc1ccc2c(-c3ccc(F)cc3)c(Oc3ccc(Cl)cc3)sc2c1 +CN1C(=N)NC(c2cccc(-c3cncc(F)c3)c2)(C2CC2)C1=O +O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1ccc(I)cc1 +Cc1ccc(S(=O)(=O)Nc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2)cc1 +CN1CCCC1CCNCC1CCN(c2ncnc3scc(-c4ccccc4)c23)C1 +CC(=O)CCCCCC(NC(=O)C1CCCCN1C)C(=O)Nc1nc(-c2ccccc2)cs1 +CC(c1ccc2ncccc2c1)c1nnc2ccc(-c3ccc4c(c3)OCCO4)nn12 +CCC(NCC1Cc2cccc(c2)OCCNC(=O)c2cc(cc(N(C)S(C)(=O)=O)c2)C(=O)N1)C(=O)NCC(C)C +CN(C)C1CCc2c(c3cc(F)ccc3n2S(=O)(=O)c2ccccc2Br)C1 +CSc1ccc(CC(=O)N(C)C2CCN(CCC(c3ccccc3)c3ccccc3)CC2)cc1 +N#Cc1ccc(Nc2nccc(C(=O)c3c(F)cc(F)cc3F)n2)cc1 +O=CC(Cc1ccccc1)NC(=O)C1CCCN1S(=O)(=O)c1cccc2ccccc12 +O=C(NC1CCC(CCN2CCC(c3coc4ccccc34)CC2)CC1)C(F)(F)F +c1cc2[nH]nc(-c3cnn(C4CCOC4)c3)c2c(OC2CCOCC2)n1 +CNCC(C)(C)Cn1c(C(C)(C)C)cc(C(=O)Nc2cccc(C(F)(F)F)c2)c1C +Brc1ccc(C(CC2CCCC2)c2cc3cccnc3[nH]2)cc1 +O=C(c1ccc(OCc2ccc(CN3CCCCC3)cc2)cc1)C1CC1 +Cc1cccc(NC(=O)NC(CS(=O)(=O)Cc2ccccc2)C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CN(C)c1ccc2cc(C(=O)NCCCCCC(=O)Nc3ccccc3N)[nH]c2c1 +O=C1NC(=O)c2c1c(-c1ccccc1Cl)cc1c2c2cc(O)ccc2n1CC[S+]([O-])c1nnc[nH]1 +C=CCSc1nc2sc3c(c2c(=O)n1-c1ccccc1)CCN(C)C3 +Cc1[nH]nc(N)c1-c1nc2cc(F)c(Br)cc2s1 +COc1ccc(Oc2cncc3sc(C(N)=O)cc23)cc1 +CC(C)CCN1CCC2(CC1)OCCc1c2cnn1-c1ccccc1 +CCCn1c(=O)c2nc(-c3ccc(OCC(=O)Nc4ccc(C(=O)O)cc4)cc3)[nH]c2n(CCC)c1=O +COC(=O)c1cc2c([nH]1)C(=O)C=C1N(C(=O)c3cc4ccc(OC)cc4[nH]3)CC3CC123 +Cc1ncsc1C(=O)N(Cc1cncc2c(F)cccc12)c1cccc(Cl)c1 +COc1ccc(CNc2nnc(NCc3ccccn3)c3ccc(C#N)cc23)cc1Cl +CN(C)CCOc1ccc(Cn2c3ccccc3c3sc4cc(O)ccc4c32)cc1 +O=C(NC(C(=O)O)c1ccc(O)cc1)c1cc2[nH]c(-c3ccco3)c(C3CCCCC3)c(=O)n2n1 +COc1ccc2nc(C=CC3C4CCCCC4CC4C(=O)OC(C)C43)ccc2c1 +Cc1cc(Nc2cc(C3CC3)n[nH]2)nc(Nc2ccc(CCNC(=O)OC(C)(C)C)cc2)n1 +CC(C)CN=C(Nc1cccc(C(=CCCCC(=O)O)c2cccnc2)c1)Nc1nn[nH]n1 +N#CCCN(CCC#N)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +Nc1cccc(SCC2COC(CCc3ccc(Cl)cc3)(Cn3ccnc3)O2)c1 +Cc1cc(C#Cc2cn(-c3cccc(C#N)c3)c(C)n2)ccn1 +COc1cc2c(cc1OC)CN(CCc1ccc(NC(=O)c3cccc4c(O)c5cccc(F)c5nc34)cc1)CC2 +O=c1nc(OCCc2ccc(Oc3ccc(Cl)c(C(F)(F)F)c3)cc2)[nH]cc1Cc1cncnc1 +CC(C)(C)OC(=O)N1CCC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +CC1(c2cc(NC(=O)c3ncc(C(F)F)cc3Cl)cc(F)c2F)CC(C(F)(F)F)OC(N)=N1 +N#Cc1cccc2c1C=Cc1ncc(-c3cccc(F)c3)cc1C2O +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 +CCCN(CCC)C1CCc2ccc3[nH]cc(CN(C)C)c3c2C1 +Fc1c(Cl)cccc1-c1nc2ccn(Cc3ccc(Br)cc3)cc-2n1 +CC1(C)CCC2(CCCCCCCCCCC(=O)O)CCC3(C)C(=CCC4C5(C)CCC(O)C(C)(C)C5CCC43C)C2C1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(-c3cn4c(n3)sc3nc(OCCN5CCNCC5)ccc34)cc2)no1 +COc1ccc2c(c1)c(CCN(C)C)cn2S(=O)(=O)c1ccccc1Cl +CCCCC(NC(=O)C(NC(=O)C(NC(=O)OCc1ccccc1)C(C)C)C(C)C)C(O)CC(=O)O +CN(C)CCNC(=O)c1cccc2nc3ccc4[nH]cnc4c3nc12 +CC(NC(=O)c1ccc2c(c1)C(=O)c1ccc(Nc3ccc(F)cc3F)cc1CC2)C1CCCCC1 +Cc1c(CCN2CCc3nc(-c4ccc5c(c4)COC5=O)oc3C2)ccc2c1COC2=O +CC1OC(C#CC2CC2)(C(F)(F)F)c2c(ccc(F)c2F)NC1=O +COc1ccc2nc3cc(Cl)ccc3c(NCCCN(C)CCCNc3c4ccc(Cl)cc4nc4ccc(OC)cc34)c2c1 +Cc1cc(C)cc(C(O)c2cc(Cl)ccc2OCC(=O)Nc2ccc(S(N)(=O)=O)cc2C)c1 +CS(=O)(=O)N1CCN(Cc2cn3c(Cl)c(-c4cccc5[nH]ncc45)nc(N4CCOCC4)c3n2)CC1 +N#Cc1nc(NCc2cccc(-c3ccoc3)c2)c2ncn(CCCO)c2n1 +CCCC1CC(OC)CC(C)=CC2CC(OC(=O)C=CCCc3coc(CCCNC(=O)OC)n3)CC(CC(=O)O1)O2 +COc1cc(OCc2cccc(OCc3ccc(I)cc3)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +CC1=C(O)C(=O)C=C2C1=CC=C1C2(C)CCC2(C)C3CC(C)(C(=O)O)CCC3(C)CCC12C +O=C1NCc2cc(-c3n[nH]cc3CN3C4CCC3CN(c3ccc(C(F)(F)F)cn3)C4)ccc2O1 +CCCCCCC1(c2ccccc2)CC(=O)C(SCCc2ccccc2)=C(O)O1 +Clc1cnc2c(Nc3ccc(N4CCOCC4)cc3)nc(-c3cccnc3)cn12 +CN(c1ncnc2[nH]ccc12)C1CC(CS(=O)(=O)N2CCC(F)(F)CC2)C1 +Cn1cc(-c2cn(-c3ccnc4c3c(C(F)(F)F)nn4-c3ccc(C(N)=O)cc3NC3CCCC3)cn2)cn1 +CCCCN(CCCC)CCCOc1ccc(-c2cn3cccc(C)c3n2)cc1 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NC1CCN(c2ncc(F)cn2)C1 +CN(C)C(=O)NC(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)n1C +O=C(O)Cc1ccc(CCCC2(O)CCN(CC3CN(CC4CCCCC4)CC3c3ccccc3)CC2)cc1 +Oc1cccc(-c2cc(-c3ccccc3)c(-c3cccc(O)c3)s2)c1 +N#Cc1ccc(Cn2cncc2CN2CCN(C(=O)c3ccccc3)CCC2c2ccccc2)cc1 +CNC(=O)CN1CCC(Oc2cc3c(Nc4ccc(F)c(Cl)c4F)ncnc3cc2OC)CC1 +O=C1N(Cc2ccccc2)C(CCCc2ccccc2)C(O)C(O)C(CCCc2ccccc2)N1Cc1ccccc1 +O=c1[nH]nc2cc(CO)c3ccc(-c4ccncc4)cc3n12 +Nc1nccn2c(C3CCC3)nc(-c3cccc(O)c3)c12 +CN1CCC(c2cc(NC(=O)Nc3ccc(Oc4ccnc(NC(=O)C5CC5)c4)cn3)cc(C(F)(F)F)c2)CC1 +CC(=NNC(=O)c1ccccc1)C(=NNc1ccc(S(N)(=O)=O)cc1)S(=O)(=O)c1ccccc1 +Cc1ccc2c(c1)CCN2C(=O)CN1CCN(Cc2ccc(Cl)cc2)CC1 +CCCCNc1ccc2ncc(-c3ccc(C(=O)NCC4CC(F)CN4)c(F)c3)n2n1 +CC(C)N(C(=O)C1C2CCCCC21)c1cc(C#CC(C)(C)C)sc1C(=O)O +Cc1cccc(C(=O)N2CCN(CCN3CCC(NC(=O)CNC(=O)c4cccc(C(F)(F)F)c4)C3)CC2)c1 +Cc1cc(-c2nc(-c3ccc(OC(F)F)c(CO)c3)n3c2CCOC(C)C3)cc(C)n1 +NC1=NC(CF)(c2nc(NC(=O)c3nn(C(F)F)cc3Cl)ccc2F)CC(C(F)(F)F)O1 +Cc1nsc(S(=O)(=O)NC(=O)c2ccc(N3CCN(Cc4ccccc4-c4ccc(Cl)cc4)CC3)cc2)c1Cl +CC(C)(C)OC(=O)NC(Cc1ccccc1)CC(O)C(Cc1ccccc1)NC(=O)c1cccc(O)c1 +CC(=O)c1ccc(-c2nnn(-c3cccnc3)c2C)cc1 +COC1(c2cccc(OCc3ccc4c(ccc(=O)n4C)c3)c2)CCOCC1 +COc1cc(N)c(Cl)cc1C(=O)OC1CN2CCC1CC2 +CN(CCCNc1ccnc2cc(Cl)ccc12)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Fc1cc(OC2CCNCCC2F)c2nc(-c3nnc4ccccn34)ccc2c1 +Cc1nccc(Nc2ncc3c(n2)CN(C(=O)NC(C)c2ccc(Cl)c(Cl)c2)CC3)n1 +CCn1nnc(C2OC(n3cnc4c(NCc5cccc(F)c5)nc(Cl)nc43)C(O)C2O)n1 +O=C(OCc1ccc(Cl)c(Cl)c1)C1(c2ccc(Cl)c(Cl)c2)CCNCC1 +Cc1ccc(Nc2nc(Cl)nc(Nc3ccc(C#N)cc3)n2)c(Br)c1 +CC(C)(C)c1[nH]cnc1C=c1[nH]c(=O)c(=Cc2cccc(N)c2)[nH]c1=O +Cc1c(CN(C)CC(O)c2cc[nH]n2)sc2c(=O)c(C(=O)NCc3ccc(Cl)cc3)cn(C)c12 +CCCN(CCC)C1CCc2c(ccc(C(O)Cc3ccccc3)c2OC)C1 +Cn1nc(C(F)(F)F)c(-c2ccc(F)cc2)c1NC(=O)Nc1ccccc1 +OC1(C(F)(F)F)c2ccccc2-c2c(-c3cnn(C45CC6CC(CC(C6)C4)C5)c3)cccc21 +O=C1C(N2CCC(c3ccc(O)cc3)CC2)CCCN1Cc1ccccc1 +Cc1ccc(C)c(C[S+]([O-])c2nc3ccccc3[nH]2)c1N +CC(C)CN1CCN(CCOc2ccc(C(=O)Nc3ccc(OC(F)(F)F)cc3)cc2-c2cncnc2)CC1 +CC1(c2ccccc2)CCCN(C(=O)NCCc2ccc3nccnc3c2)C1 +Cn1c2c(c3ccc(-n4ccc(-c5ccc(Cl)cn5)cc4=O)cc31)CCNC2 +CNC(=O)Nc1nc2ccc(-c3cnc(OC)c(NS(=O)(=O)c4ccc(F)cc4)c3)cc2s1 +O=C(Nc1cc(Cn2c(=O)[nH]c(=O)c3ccccc32)cnc1F)C1CCN(CCC2CC2)C1 +NC1=NC2(c3ccc(F)cc3F)COC(c3ncc(F)cn3)CC2CS1 +CC(C)Oc1ccc(-c2n[nH]c3ccc(C(=O)NC4CCCC(O)(Cc5ccccc5F)C4)cc23)cn1 +COc1ccc(S(=O)(=O)N2CCc3cccc(-c4ccc(O)cc4)c32)cc1 +N=C(N)c1ccc(CNC(=O)C2CCCN2C(=O)C(NS(N)(=O)=O)C(c2ccccc2)c2ccccc2)s1 +Cc1c(-c2cccc(C(F)(F)F)c2)c(=O)c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1CC1CC1 +Cc1ccccc1C(C(=O)NC1CCCCC1)N(C(=O)Cn1cncn1)c1cccc(F)c1 +CN(Cc1n[nH]c(O)n1)C(COCc1cc(Cl)cc(Cl)c1)c1ccccc1 +COC(=O)CCCC=CCC1C(=O)C(C)(C)C(O)C1C=CC(O)Cc1cc2ccccc2s1 +CONC1=NC(=O)C(=Cc2cc(C(C)C)c(O)c(C(C)C)c2)S1 +CC1=CC(C)(C)C2(O)COC(c3ccc(O)cc3Cl)C1C2 +Cc1ccccc1Oc1cc(N2CCC(Oc3ncc(F)c(N)n3)CC2)ncn1 +Fc1ccc2c(-c3nc4cc(N5CCC(N6CCCCC6)CC5)ccc4[nH]3)[nH]nc2c1 +Nc1nc(Nc2ccc(C(=O)O)cc2)nc(OCC2CCCCC2)c1C=O +O=C1NC(=O)C(c2ccccc2[N+](=O)[O-])=C1Nc1cccc(O)c1 +CCCn1c(=O)c2[nH]c(-c3ccc(OCC(=O)Nc4ccc(C(=O)c5ccccc5)cc4)cc3)cc2n(CCC)c1=O +COc1cc2nc(-c3ccc(C)c(Br)c3)cc(O)c2cc1-c1cnco1 +O=C(Nc1cc(CNC2CCCCC2)[nH]n1)Nc1cccc2c1C1CCCN1C2=O +CCC(CC)Oc1cc(C)c(-c2cc(-c3cnc(NC(=O)NC)s3)nc(-c3cnccn3)n2)c(C)c1 +COc1cc(C(=O)O)ccc1Nc1ncc2c(n1)-c1c(nn(C)c1C(C)c1ccccc1)CC2 +Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccn2)cc1-n1cc(-c2cncc(N(C)CCN3CCCC3)c2)nn1 +CCCCOC(=O)C1=CCC23CCC(C(C)(C=CC=C(C)C(=O)O)OC2=O)C3(OC(C)=O)CC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3cc(OCC4CC4(F)F)ncc3F)C2)cc1 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1-c1ccccc1 +COC(=O)C1=C(c2ccc3ccccc3c2)CC2C(O)CC1N2C +CCC(CC)c1cc(C)n2nc(-c3cc4c(cc3C)OCO4)c(C)cc12 +CC(=O)N1C2C=C(CN3CCC(Nc4ccc5ccc(C(F)(F)F)cc5n4)CC3)CC1CCC2 +CC(NC(=O)C(=O)Nc1ccc2c(c1)CCC2)C(=O)NC(CC(=O)O)C(=O)COc1c(F)c(F)cc(F)c1F +O=C(NO)c1ccc(NC2CCN(Cc3ccccc3)C2=O)cc1 +CN(C)C1CCN(Cc2ccc3c(-c4ccc(F)cc4)cc(C(N)=O)nc3c2)C1 +CC(C)n1cc(Nc2[nH]nc3ccnc(OC4CCOCC4)c23)cn1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC1CNC(=O)CCCCOC(=O)C(O)C(CC2CCCCC2)NC1=O +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(CO)C(F)(F)F)ncc23)ccn1 +CCCc1nc(-c2cc(N)ccn2)c(-c2ccccc2C)s1 +O=C1OC2(CCN(c3nc4cc(Br)ccc4[nH]3)CC2)c2ccccc21 +COc1cc2c(Nc3ccc(Cl)c(Cl)c3)ncnc2cc1OCC1CN(C(=NC#N)N2CCN(C)CC2)CCO1 +COc1cccc2c1CCN=C2c1sc2cccc(C)c2c1Cl +CC(=O)N1N=C(c2ccc(O)cc2O)CC1c1cccc(O)c1 +c1csc(C2CN3CCCC3c3cc(OCCCN4CCCCC4)ccc32)c1 +Cc1c(S(=O)(=O)NCCCN2CCN(c3noc4ccccc34)CC2)sc2ccc(F)cc12 +Cc1nc(C(=O)N2C3CCC2C(Nc2cnc(C(F)(F)F)cn2)C3)c(-c2ccc(F)cc2)s1 +COc1cccc(-c2c(C)n(Cc3c(F)cccc3C(F)(F)F)c(=O)n(CC(C)NC3CCCC3)c2=O)c1 +CSc1cc(F)c(F)cc1-c1ccc(OCc2cccc(C(=O)N3CCCC3C(=O)O)c2)cc1 +Nc1ncc(-c2cc(N3CC4CC3CO4)nc(N3CCC(F)(F)CC3)n2)cc1OC(F)F +CC(C)CC(NC(=O)C(NC(=O)c1cccc(-c2ccccc2)c1)C(C)O)B(O)O +CCc1sc(SCc2cc(N3CCOCC3)cc(NCc3cccc(C)n3)n2)nc1CF +CCCCCn1cc(C(=O)NC2CCCCC2)c(=O)n2nc(-c3ccco3)cc12 +CNC(C)C(=O)Nc1cc(-c2nc(C)nc3nn(C)c(C)c23)cc(C#Cc2cccs2)n1 +Oc1ccc(OCC(O)CN2CCN(c3ccc(Cl)cc3)CC2)cc1 +CCCCOc1ccc(S(=O)(=O)N2CCC(NCC(O)c3ccc(O)c(NS(C)(=O)=O)c3)C2)cc1 +COc1cc(C=CC(=O)c2cccc(NC(=O)c3ccc(Cl)cc3Cl)c2)ccc1O +COc1cc(C(=O)N2C(c3nccs3)C(CO)CC2(CC(C)C)C(=O)O)ccc1C(C)(C)C +O=C(CCCCCCC(=O)Nc1ccc(-c2cn(CC(O)c3cccc(Br)c3)nn2)cc1)NO +CC(=O)OC(c1ccc(Br)cc1)C(Cn1ccnn1)c1ccccc1 +CCNC(=O)Nc1ccc(-c2nc(N3CC4CCC(C3)O4)nc3c2C(=O)N(CC)CC(C)(C)O3)cc1F +COC1CCN(C2CCC(NC(=O)c3cc4c(C)nn(C5CCCCC5)c4s3)CC2)CC1 +CS(=O)(=O)N1CCN(c2cc(-c3n[nH]c4ccc(-c5cnccn5)cc34)ncn2)CC1 +Cn1cc(-c2ccc(Cc3n[nH]c4ccc(C(=O)N5CCC(O)C5)cc34)cc2)cn1 +CN1C(=O)Cc2ccc(-c3ccc(CC(C#N)NC(=O)C4NC5CCC4C5)c(OCc4ccccc4)c3)cc21 +Cc1cc2[nH]c(=O)c3cnn(C4CCOC4)c3c2cc1C(=O)N1CCC(OCC(C)(F)F)CC1 +Cc1c2c(cn1C)-n1c(C)nnc1C(CC(=O)N1CC3(CCS3(=O)=O)C1)N=C2c1ccc(Cl)cc1 +CC(C)Cc1cc(-c2ccc(CCNCC(O)c3ccc(N)nc3)cc2)ccc1C(=O)O +Nc1ccncc1C(O)CNCCc1ccc(-c2ccc(C(=O)O)c(OC3CCCCC3)c2)cc1 +CC12CCC(=O)C=C1NCC1C2CCC2(C)C(C(=O)N3CCNCC3)CCC12 +COc1cc2ncc(C(N)=O)c(Nc3ccccc3Br)c2cc1OC +Cc1cccc(C)c1-n1c(=O)c2cnc(Nc3ccc(N4CCN(C)CC4)cc3)nc2n2c3ccccc3nc12 +Cc1ccc(-c2noc(C3CC(F)(F)C3)n2)cc1NC(=O)c1cnc2ccc(-n3cncc3C)cn12 +Cn1c(C2(C)CC2)cc(=NC(=O)c2cc(C(F)(F)F)ccc2OCC(C)(C)O)n1CC1CCCO1 +CN1CC2(C1)CN(C(=O)Cn1cc(NC(=O)c3cnn4cccnc34)c(-c3cc(Cl)ccc3OC(F)F)n1)C2 +N#Cc1ccc2c(c1)C(N1CCCC1=O)=CC(CF)(CF)O2 +CCCn1cc(C#N)c2ncnc(N3CCN(CCc4ccccc4)CC3)c21 +CCN1C2CCC1CC(c1ccnc3c(-c4ccc(Cl)c(OC)c4)c(-c4ccncc4)nn13)C2 +CC(C)Nc1ncc2c(n1)CN(C(=O)NCc1ccccc1)CC2 +COc1ccc(C(=O)Nc2c(Cl)c[n+]([O-])cc2Cl)c2ccnn12 +Cc1cn(Cc2ccc(Cl)cc2Cl)c2c(-c3ccc(NS(=O)(=O)c4cc(Cl)c(Cl)s4)nc3)cc(F)cc12 +CC(C)Oc1ccc(-c2nc(-c3cccc4c3CCC4NCCN3CCOCC3)no2)cc1C#N +CC(C)(C)OC(=O)N1CCC(c2coc3c(N4CCCc5cc(S(C)(=O)=O)ccc54)ncnc23)CC1 +CCNC1CCN(c2ccc(Nc3ncc(Cl)c(Nc4ccccc4S(=O)(=O)NC(C)C)n3)c(OC)c2)C1 +Cn1c(=O)c(-c2c(Cl)cccc2Cl)cc2cnc(Nc3ccccc3)cc21 +CCC1C(=O)N(C)c2cnc(-n3ccnc3-c3ccc(F)cc3)nc2N1c1ccc(F)cc1 +O=C(c1ccccc1)N(c1ccccc1)C1CCN(Cc2ccccc2)CC1 +COC(=O)Cc1ccc(C#CC2(CN3Cc4ccc(OC)cc4C3=O)NC(=O)NC2=O)cc1 +COc1cc(OC)cc(C(=O)Nc2ccc(C)c(-n3ccn4nc(-c5cccnc5)cc34)c2)c1 +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC(CC(C)C)B(O)O +CC#CCOc1ccc(S(=O)(=O)NC(Cc2c(C)n(Cc3ccc(C#N)cc3)c3ccc(OC)cc23)C(=O)O)cc1 +CC1(F)CCN(c2nc(-c3cnc(N)c(OC(F)F)c3)cc(N3CCN4CCCC4C3)n2)C1 +COc1cc(OC)cc(C(=O)N(CCN2CCC(OCC(=O)O)CC2)c2ccc(C)cc2)c1 +CCCCCCCCCCCCn1nnc(C(NC(=O)c2ccnc(SC)c2)c2ccccc2)n1 +FC(F)(F)c1ccc(C(NCC2CCCCC2)c2cccnc2)cc1 +CC(C)(Nc1nc(NO)nc(Nc2ccc3ncsc3c2)n1)c1ccccc1 +CC(c1nc(-c2ccc(S(C)(=O)=O)cc2)no1)C(N)C(=O)N1CCCC1 +CC1=CC(=O)N(Cc2c(F)cccc2F)S(=O)(=O)O1 +O=C(NO)c1ncc(CCc2ccc(F)cc2)c(CO)c1O +CC(C)(C)c1ccc(-n2cc(-c3cccc(NC(=O)CCCCCCC(=O)NO)c3)nn2)cc1 +Nc1nc(-c2ccco2)c2c(n1)-c1ccccc1C2=O +C=C1CCC2C(C)(C(=O)OC)CCCC2(C)C1CCc1ccc2c(c1)C(=O)C=CC2=O +Cc1nc(CO)nc(N2CC(C)N(c3ccnc(C(C)O)n3)C(C)C2)n1 +O=C1CCCCC1CN1CCN(CCOC(c2ccccc2)c2ccccc2)CC1 +O=C1C(=O)N(Cc2ccc(Br)cc2)c2c(Br)cc(Br)cc21 +O=C(C1CC(Oc2ccccc2)CN1)N1CCCN(C2CCC2)CC1 +CC(=O)NC(C)c1ccc(C#Cc2ccc3c(c2)CCO3)cc1 +Cc1cc2c(cc1N1C(=O)c3cccc4c(Cl)ccc(c34)C1=O)n(C)c(=O)n2C +COc1cc2cc(Cl)ccc2nc1-c1ccc(N(Cc2ccsc2)C(=O)c2ccc(O)cc2O)cc1 +CC(C)Oc1ccccc1C1C(C(=O)C(C)C)C(=O)C(=O)N1c1ccc(-c2ccon2)cc1 +COc1ccc(C2=NN(Cc3ccccc3)C(=O)CC2)c2cc(C(C)C)nn12 +COc1ccc(N(Cc2nc(-c3ccccc3)cs2)S(=O)(=O)c2ccccn2)cn1 +CC(CCC(=O)Nc1ccc(S(N)(=O)=O)cc1)C1CCC2C3C(O)CC4CC(O)CCC4(C)C3CC(O)C12C +c1ncc(-c2cc3sc(N4CCC(N5CCCCC5)CC4)nc3cn2)cn1 +Cc1nn(C2CCCCC2)c2sc(C(=O)NCC(C)(C)CN3C(=O)CNC3=O)cc12 +COC(=O)CC1CCN(c2ccc(Nc3ncc4c5ccnc(F)c5n(C5CCCC5)c4n3)nc2)CC1 +Cc1nc2cnccc2n1CC1CCN(C(=O)CC(C)(C)c2ccccc2)CC1 +COc1cc2nccc(Oc3ccc4c(c3)OCCN4C(=O)Nc3ccccc3)c2cc1OC +Cc1cnn(CC(=O)Nc2cncc(C(=O)c3cn(C(C)C)c4ccncc34)c2)c1 +Brc1ccc(CCN(Cc2ccc(Oc3ccccc3)cc2)Cc2c[nH]cn2)cc1 +NC1CCN(c2ccc(Nc3c(C(=O)C4CC4)cnc4ccc(-c5cc(F)c(O)c(Cl)c5)cc34)cn2)C1 +COc1ccc(C(C)(C)C)cc1NC(=O)c1ccc(C)c(Nc2ncnc3cnc(N4CCCN(C)CC4)nc23)c1 +O=C(Nc1ccc(C(F)(F)F)cn1)N1CC=C(c2ncc(CCO)cc2Cl)CC1 +Cc1c(C#N)ccnc1OC1CCC(C)N(C(=O)c2ccncc2-c2ccccc2)C1 +Cc1cncc(-c2c[nH]c3ncnc(N4CCCC(C)C4)c23)c1 +CS(=O)(=O)N1CCC(CCC(=O)Nc2ccc(F)c(F)c2)(c2ccc(-c3cccc(C#N)c3)cc2)CC1 +O=C(NCc1ccccn1)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +Cc1ccc(-n2nc(C3CCN(S(C)(=O)=O)CC3)cc2NC(=O)c2cnn3cc(NC=O)cnc23)nc1 +N#Cc1cccc(S(=O)(=O)C2CCN(CCc3ccc(F)cc3F)CC2)c1 +[H]C([H])(c1ccccc1)N1CC(C)N(C(=O)Nc2cccnc2)C(C)c2ccncc21 +COCCC(=O)Nc1cccc(-c2n[nH]c3ccc(-c4nn[nH]n4)cc23)c1 +Cc1ccc(-n2nc(C(C)(C)C)cc2NC(=O)Nc2ccc(OCCc3ccnc(N)c3)c3ccccc23)cc1 +Nc1nc(-c2cccc(C(=O)N3CCN(Cc4ccccc4)CC3)c2)cn2nc(-c3ccco3)nc12 +Nc1ccc(C2CCCCC2)nc1C(=O)Nc1cnccc1C1CCCC(N)C1 +O=C(Nc1ccc(CCO)cc1)C1CCN(C(=O)Cn2c(=O)sc3ccc(Cl)cc32)CC1 +CC(C(=O)N(C)O)c1ccc2c(c1)C(=O)c1ccccc1CO2 +COC(=O)c1cccc(COC(c2ccc(C#N)c(-c3ccccc3C)c2)c2cncn2C)c1 +O=C(O)COc1ccc(Cl)cc1C1c2scnc2CCN1C(=O)NCc1ccccc1F +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)Nc1ccccc1CC1c2ccccc2CCN1C +COc1cc(O)c2c(c1)C=CCC(O)C(O)C(=O)C=CC(C)C(C)OC2=O +C=CCN1CCC23c4c5ccc(O)c4OC2C(NC(=O)c2cccc(N)c2)CCC3(O)C1C5 +COc1c(C(=O)Nc2ccc(C)cc2C(=O)Nc2ccc(Cl)cc2)sc2ccccc12 +CCOc1ccc(CC(NC(=O)c2sc(C)nc2C)C(=O)NC(Cc2ccccc2)C(=O)NCc2ccc(CN)cc2)cc1 +COCCNS(=O)(=O)c1ccc(C)c(C#Cc2cc(Cl)ccc2OCC(=O)O)c1 +COc1cc(-c2cncn2C)ccc1Nc1cc2cc(-c3cnn(C)c3)ccc2cn1 +COc1ccc(NC(=O)Nc2ccc(OS(N)(=O)=O)cc2)cc1 +CN(CC=CCOc1ccc(C(=O)c2ccc(Br)cc2)cc1)C1CC1 +O=C(CCCCCNc1c2c(nc3ccccc13)CCCC2)NCCc1c[nH]c2ccccc12 +Cn1c(=O)c2c(-c3ccccc3)n3c(c2n(C)c1=O)C(c1ccc(Cl)o1)OC(C)(C)C3 +COc1cc(N2CC3CN(CCO)CC(C2)O3)ccc1Nc1ncc(Cl)c(-c2cnc3ccccn23)n1 +NS(=O)(=O)c1ccc(CCN=Cc2cc(Br)ccc2O)cc1 +COc1ncc(-c2ccc3nc(N)nc(-c4ccncc4)c3c2)cc1NS(=O)(=O)c1ccc(F)cc1F +O=C(O)c1ccc(-c2ccc(C(Nc3ccccc3F)C(=O)N3CCCC3c3ccccc3F)cc2)cc1 +CCC(Nc1nc(NCc2ccc(C(F)(F)F)nc2)c2ncn(C(C)C)c2n1)C(C)O +C=C(C)n1c(=O)n(Cc2nc3ccccc3n2CCCCCCO)c2ccccc21 +CN1C(=O)N(CC2CC2)CC1C(=O)NCc1ccc(Cl)cc1Cl +CN(C)C(=O)Cn1c(-c2ccccc2)c(C2CCCCC2)c2sc(C(=O)O)cc21 +O=C(O)COc1cccc(-c2ccccc2-c2cc(-c3ccccc3)c(-c3ccccc3)o2)c1 +CCOC(=O)NC1CCC2C(C1)CC1C(=O)OC(C)C1C2C=Cc1ccc(-c2ccc(OC)cn2)cn1 +CCn1cc(-c2cc3c(-c4cccc(N5CCNC(C)(C)C5)n4)n[nH]c3cn2)cn1 +N#Cc1cccc(Nc2cc(-c3ccccc3)nc3c2C(=O)NCC3)c1 +O=C(O)CCCC=CCC1C2CCC(C2)C1NS(=O)(=O)c1ccc2ccccc2c1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OCc1ccc(CO)cc1 +Cc1c(C)c2ccc(OCC=CC3=CC(=O)C(C)(C)O3)cc2oc1=O +COC(=O)COc1cc(Br)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +NC(C(=O)N1CCCC1C(=O)NCCc1c[nH]cn1)C(c1ccccc1)c1ccccc1 +CCCCc1cnc(C(CCCC)Cc2ccc(-c3ccccc3C(=O)O)cc2)[nH]1 +O=C(NC1CCCCC1)OCC1OC(n2cnc3c(NC4CCOC4)ncnc32)C(O)C1O +C=Cc1ccc(-c2nnc3ccc(Sc4ccc(F)cc4F)cn23)c(C)c1 +Cc1ccc2c(c1Br)CCN2C(=O)Nc1ccc(Oc2cccnc2C)nc1 +CC(C)NC(=N)c1cccc(-c2cc3ccc(C(=N)NC(C)C)cc3o2)c1 +NC1CN(c2cc(-c3ccsc3)ncn2)CC1c1cc(F)c(F)cc1Cl 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+COc1ccc2c(c1)OC(=Cc1cc[n+](Cc3cccc(F)c3)cc1)C2=O +Cc1nc2cccnc2n2c(-c3cc(OCCC(C)O)ccc3Cl)nnc12 +CC(NP(=O)(COCCn1cnc2c(N)ncnc21)NC(C)C(=O)OCC(C)(C)C)C(=O)OCC(C)(C)C +CN1C(=O)C(c2ccc(OC(F)F)cc2)(c2cccc(CCCC(F)(F)F)c2)N=C1N +Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(C[N+](C)(C)CCCO)cc2)CCO3)cc1 +CN(C)CC(=O)Nc1cccc2c1nc(C(F)F)n2-c1nc(N2CCOCC2)nc(N2CCOCC2)n1 +N#Cc1cccc(-c2cc(NC(N)=O)c(C(=O)NC3CCCNC3)s2)c1 +O=C(COc1ccc(Cl)cc1C(=O)c1ccccc1)Nc1ccccc1 +CN(Cc1cccc2ccccc12)C(=O)c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 +COc1cc(C)cc(-c2nn(C)cc2-c2cc(NCCCCO)nc(-c3cccnc3)n2)c1 +COc1ccc(C(=O)NCCc2ccccc2)cc1C(=O)NCCc1ccccc1 +Cc1ncsc1C(=O)N(Cc1cc(=O)[nH]c2c(F)c(F)ccc12)c1cccc(Cl)c1 +O=C(Nc1ccccc1F)NC1CCN(Cc2ccc(-c3nnc4n3-c3cccnc3Nc3ccccc3-4)cc2)CC1 +O=C(CN1CC(CNCc2ccccc2)=CCC(NC(=O)c2ccc3ccccc3c2)C1=O)NC1CC(=O)OC1O +CC1CCCC1NC(=O)C1CCN(c2nc3cc(Cl)ccc3o2)CC1 +COc1ncc(-c2sc3ncnc(-c4ccncc4)c3c2C)cc1NS(=O)(=O)c1ccc(F)cc1F +CC(C)Cc1cc(=O)nc(Nc2ccc(Cl)c(S(=O)(=O)C(C)C)c2O)[nH]1 +CCC1c2c(C3=CCN(S(C)(=O)=O)CC3)[nH]c3nccc(c23)-c2cc(F)ccc2N1C +Cn1cc(-c2ccc3[nH]nc(-c4cc(N5CCC(F)(F)C5)ncn4)c3c2)cn1 +CC(C)N1C(=O)C(NC(=O)C(Cc2ccc(F)cc2)NC(=O)OC(C)(C)C)CCc2ccccc21 +CCOc1ccc2ncnc(NCc3ccc4c(c3)OCO4)c2c1 +NCc1cn(S(=O)(=O)c2ccc(N)cc2)c2ccccc12 +O=C(CCCN1CCN(CC=Cc2ccccc2)CC1)NC1c2ccccc2CSc2ccccc21 +CCCn1c(=O)[nH]c2nc(-c3cnn(Cc4ccccc4)c3)[nH]c2c1=O +CS(=O)(=O)NC(=O)c1ccc(-c2ccc(CCNCC(O)c3ccccc3)cc2)cc1OC1CCCCC1 +CN(C)Cc1ccc(-c2[nH]c3cccc4c3c2CNC4=O)cc1 +CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)C2c1ccc(Sc2nc3cc(F)c(F)cc3[nH]2)o1 +CC1CN2CCCC2CN1C(=O)N1Cc2c(NC(=O)c3ccnn3C)n[nH]c2C1(C)C +COc1cc(NC2=CC(=O)c3ncncc3C2=O)cc(OC)c1OC +CCc1nc(N)nc(N)c1C#CCc1cc(-c2ccccc2C(=O)O)ccc1OC +CCCCCc1ccc(NS(=O)(=O)c2ccc(N3CCNC3=O)cc2)cc1 +COc1ccc(-c2c(SC)nn(-c3c(Cl)cc(C(F)(F)F)cc3Cl)c2N)cc1 +Cc1cc(=O)oc2c1ccc1oc(C(=O)c3ccccc3)c(-c3ccco3)c12 +COc1cc(O)ccc1C=CC(=O)OCCCc1ccc(O)cc1 +CCCN1C(=O)c2cc(N)ccc2Oc2c(C)cc(C)cc21 +CCC(=O)N1Cc2nc(-c3ccccc3)nn2-c2cc(C)ccc21 +O=C(Nc1ccc(C2CNCCO2)cc1)c1ccn(-c2ccc(Cl)cn2)n1 +CC(C)c1ccc2c(Nc3cc(C(=O)NC(C)c4cccc(Br)c4)ccc3Sc3ccc(N)cc3)ncnc2n1 +CCC(C)Oc1ccc2c(c1Cl)CCN(Cc1ccc(C(C)NC(C)=O)cc1)C2 +CC(C)C1NC(=O)CC2C=CCCSSCC(NC1=O)C(=O)NCc1cc(OC(F)(F)F)ccc1CC(=O)O2 +CN1CCN(C(=O)c2ccc(-c3ccc4ncnc(Nc5ccc(OCc6cccc(F)c6)c(Cl)c5)c4c3)o2)CC1 +CCC(C(=O)O)n1c(=O)c2ncccc2n(Cc2nsc3cc(C)cc(C)c23)c1=O +NCc1ccc2c(c1)c(C1CCN(CCN3CCNC3=O)CC1)cn2-c1ccc(F)cc1 +Cc1ncccc1C(C#N)N1CCN(C(=O)CN(C=O)C(c2ccccc2)c2ccccc2)CC1 +Cc1cccc(C2CC2COc2cc(NCc3cnn(C)c3)c(=O)n(C)n2)n1 +Nc1nccc(Oc2ccc(NC(=O)c3cccn(-c4ccc(F)cc4)c3=O)cc2F)c1C#CCO +COc1ccc(C2CC3(N(C)C)CCNC2C(c2ccc(OC)cc2)C3)cc1 +Cc1ccc(-c2c(=O)n(CCCCN3CCC(c4c[nH]c5ccccc45)CC3)c(=O)n3ccccc23)cc1 +CC(C)(C)c1ccc(OCC2CN(c3cccc(C#N)c3)C(=O)O2)cc1 +O=C(O)c1[nH]c2cc(Cl)cc(Cl)c2c1CN1CC(=O)N(c2ccc(Cl)cc2)C1=O +CNc1nc(Nc2cc(OC)c(C(=O)N3CC(C)OC(C)C3)cc2Cl)ncc1C(F)(F)F +COc1ccc(-c2cnc(N)c(-c3ccc(C(N)=O)cc3)c2)cc1OC +FC(F)(F)c1ccc2[nH]c(-c3ccc(N4CCC(c5ccccn5)CC4)nc3)nc2c1 +CC(C)(C)c1cc(N2CCC(=O)NC2=O)cc(C(=O)NCc2ccccc2)c1O +Cc1ccc2on(CC3CC4c5ccccc5Oc5ccc(Br)cc5C4O3)c2c1 +CC(C)C(NS(=O)(=O)c1ccc2c(c1)oc1ccc(NS(C)(=O)=O)cc12)C(=O)O +CCc1c(N)ncnc1N1CCC(c2nc(-c3ccc(F)c(C(F)(F)F)c3)cn2CCN2CCC(F)(F)C2)CC1 +O=C(Nc1cc[nH]c(=O)c1)c1cc(OC(F)(F)F)ccc1Oc1ccccc1 +CN(CCN1CCCCC1)C(=O)N1CCC(c2ccccc2)CC1 +O=C(c1c(F)cccc1-c1ncccn1)N1CC2CC(Oc3ccc(C(F)(F)F)cn3)C1C2 +N=C(N)NCC(=O)NCC1(Nc2ccccc2)CCN(Cc2ccc3ccccc3c2)CC1 +COc1ccc(CN(C)CCCOc2ccc(NC(=O)c3cccc4c(O)c5cccc(C)c5nc34)c(C)c2)cc1OC +NCCc1cn(S(=O)(=O)c2ccc(Cl)c(Cl)c2)c2ccccc12 +CS(=O)(=O)N1CCN(CCC(CS(=O)(=O)c2ccc(Oc3ccc(OC(F)(F)F)cc3)cc2)N(O)C=O)CC1 +Cc1ccc(CC(=O)O)cc1-c1ccc(F)c2c1CN(C(=O)OCc1ccccc1)CC2 +CCOc1nc(C)c(Nc2nc(Cl)cn(C(C)C3CC3)c2=O)cc1C +CCN1CCN(c2nc3ccccc3c3c2oc2ccccc23)CC1 +Cc1cccc(-c2[nH]c(CNC(=S)c3ccccc3)nc2-c2ccc3ncnn3c2)n1 +CC(C1CC1)N(Cc1cnc[nH]1)c1cccc(Cl)c1 +COC(C(=O)NC1CCC(OC(=O)C=Cc2ccccc2)CNC1=O)C(O)C(O)C(O)C=CC(C)(C)C +CC(C)c1ccc2nc3ccc(C(=O)N(C)CCCCc4cccnc4)cn3c(=O)c2c1 +CCSc1nnc2c(n1)OC(c1ccco1)N(C(C)=O)c1ccccc1-2 +O=C(Nc1ccc(OCCN2CCOCC2)c2ccccc12)c1cc(F)cc(N2CCOCC2)c1 +COc1ccc2c(c1)C(=O)N(CC1(C#Cc3nc(N)ccc3O)NC(=O)NC1=O)C2 +Nc1nc(Cl)c(C#Cc2ccncc2)c(NC2CC(CO)C(O)C2O)n1 +N#Cc1ccc(COc2ccc3c(=O)cc(N4CCOCC4)oc3c2)cc1 +CCC(COC)N(C)c1nc(C)nc2c1nnn2-c1ccc(C(C)C)cc1Br +CC(C)(C)c1ccc(NC(=O)c2ccc(-c3ncccc3C#N)cc2)cc1 +COc1ccc(-n2nc3c(N(C(=O)c4ccccc4)C(=O)c4ccccc4)nc4ccccc4n3c2=O)cc1 +N#Cc1cc(NC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)ccc1Oc1ccnc(NC(=O)C2CC2)c1 +CC1CNC(=O)c2[nH]c3ccc(C(=O)Nc4cccc(C#N)c4)cc3c21 +COc1ccc(OC)c(NC2=CC(=O)c3c(cnc4c3C(=O)CCC4)C2=O)c1 +O=C(O)CCCCCCC(CNS(=O)(=O)c1ccc(Cl)cc1)c1cccnc1 +O=S(=O)(c1cccc(C(F)(F)F)c1)c1cc(F)c2oc3c(c2c1)CNCC3 +CCOP1(=O)N=C(C2=C(O)C(C(C)(C)C)N(CCC(C)(C)C)C2=O)Nc2ccc(OCC(N)=O)cc21 +CCOC(=O)N1CCC(N2CCC(C3(c4ccc(S(=O)(=O)c5ccc6c(c5)OCO6)cc4)OCCO3)CC2)CC1 +COC(=O)c1c(Br)c(OC)c2c(c1-c1c3c(c(OC)c(Br)c1C(=O)OC)OCO3)OCO2 +O=C(O)CC(NC(=O)c1cnc(CNS(=O)(=O)c2ccc(O)c(C(=O)O)c2)s1)C(=O)CSCc1ccccc1Cl +N#Cc1nc(NCc2cccc(-c3ccccc3C(F)(F)F)c2)c2ncn(CCCO)c2n1 +CC(C)(C)C(NC(=O)c1cc(OCC(F)(F)F)c(N2CC(F)(F)C2)cn1)C(N)=O +CC(=O)NC(C)(C)C#Cc1cnc(Oc2ccc(OC(C)C)cc2)s1 +CCNc1n[nH]c2c(C)c(NC(=O)NC(C)c3ccccc3)ncc12 +C=CC(=O)Nc1cc2c(Nc3ccc(Br)cc3F)ncnc2cc1OCCNC(=O)C1CCCN1C(=O)CC +NC(=O)c1ccc(NC2CCCCC2N)cc1Nc1ccccc1Br +Nc1ncc(-c2ccncc2)nc1-c1ccc(C(F)(F)F)nc1 +N#CC1(NC(=O)C2Cc3ccc(cc3)OCC=CCCc3ccccc3C(=O)N2)CC1 +CCCCc1nnc(C(=O)C(NC(=O)Cn2c(-c3ccc(F)cc3)ncc(N)c2=O)C(C)C)o1 +N#Cc1cccc(C(=O)Nc2ccc(C3CNCCO3)cc2F)n1 +COc1ccc(COc2ccc(-c3cc(C=C4CN5CCC4CC5)on3)cc2)cc1 +CCCCCCCCCCCCCCCC[n+]1ccn(Cc2ccccc2)c1C +O=C(CCCc1ccccc1)OC(CCCN1CCC(O)(c2ccc(Cl)cc2)CC1)c1ccc(F)cc1 +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nccn5c4)c3c2)CC(C(=O)O)C1 +CN(C)CCN(C)C(=O)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)N1CCCC1C(=O)O)C(CS)Cc1ccccc1 +Nc1nccc(-c2cc(Cl)ccc2Oc2cc(F)c(S(=O)(=O)Nc3ncns3)cc2F)n1 +CCc1nn(Cc2cccc(C)n2)c2cccc(NC(=O)c3cnc4cc(OCCN5CCN(C)CC5)ccn34)c12 +O=C1C2Cc3c([nH]c4ccccc34)C(c3ccc4c(c3)OCO4)N2C(=O)CN1C1CCN(CC2CCCCC2)C1 +NS(=O)(=O)c1ccc(-n2nc(C(F)F)cc2-c2ccc(Cl)cc2)cc1 +Cc1ccccc1-c1ccc2c(ccc3sc4c(c32)NCC(C)NC4=O)n1 +Cn1ncnc1-c1c2c(=O)n(C)c(=O)n(CC3CC3)c2nn1Cc1ccnc2ccc(Cl)cc12 +Cc1cccnc1NCC1CCC(NC(=O)c2cc(C(F)(F)F)ccc2Cl)CC1 +O=C(NNC(=O)C12CC3CC(CC(C3)C1)C2)c1ccncc1 +CC(C)Oc1ccc(-c2nc(-c3ccc4c(CCC(=O)O)c[nH]c4c3)no2)cc1Cl +CN(C)c1nc2ccc(NC(=O)c3c(C(=O)N4CC(F)C4)cnn3C)cn2n1 +Cc1c(C(=O)N2CCN(C(=O)c3ccc(Br)cc3)C(c3ccc(Cl)cc3)C2)cnn1-c1cccc(C#N)c1 +COc1cccc2c(C3=C(c4cn(C)c5cc(I)c(F)cc45)C(=O)NC3=O)coc12 +Cc1cc(-c2nnc3c4c(c(OCc5ccccn5)nn23)CCCC4)no1 +c1ccc(N2CCN(CCCOc3ccc(-c4nc5ccccc5[nH]4)cc3)CC2)nc1 +COc1cccc2c1OC(CN1C3C=C(c4ccc5ccccc5c4)CC1CC3)CO2 +O=c1[nH]c(C2CCC(c3ccccc3)CC2)c(Cc2c(Cl)cccc2Cl)c(=O)[nH]1 +CC(=O)Nc1ccccc1Nc1ccc(C(=O)c2ccccc2C)c(Cl)c1 +COc1ccc(S(=O)(=O)n2ccc3ccnc(-c4ccc([N+](=O)[O-])cc4)c32)cc1 +CCCCC(OP(=O)(O)CCCCc1ccccc1)C(=O)N1CCCC1C(=O)O +O=C(Cc1ccccc1)Nc1n[nH]c2ccc(N3CCCS3(=O)=O)cc12 +O=C(O)CCCOc1cc(Cl)c2c(c1)C(O)(C(F)(F)F)c1ccccc1-2 +CCS(=O)(=O)N1CCCCC(=O)N2CCc3cc(ccc32)Nc2ncc(C(F)(F)F)c(n2)NCc2ccccc21 +CCOc1ccccc1-c1cc2[nH]c3ccc(O)cc3c2c2c1C(=O)NC2=O +Cc1cccc(-c2cc(C(=O)NCc3ncccc3C)nc(N)n2)c1 +Cc1ncc(C(=O)N2CCC(c3ccc(C#N)cc3)CC2)cc1NC(=O)c1ccc(N2CCCC2)nc1 +Cc1cccc2cc(C=CC(=O)c3ccc(Br)s3)c(Cl)nc12 +O=C(Nc1ccc(N2CCN(C(=O)C3CCC(C(=O)O)CC3)CC2)nc1)c1nc(-c2ccccc2)oc1C(F)(F)F +COC(=O)CNCCCNC(=O)c1cc2nccc(Oc3ccc(NC(=O)Nc4cc(C)ccc4F)c(F)c3)c2s1 +Cc1ccc2c(c1)nc(C)n2C1CCC(NCC2Cc3ccccc3C2)CC1 +CC(C)(C)c1cc(NC(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)n(-c2ccccc2)n1 +COc1cc(OC)c2c(C)[n+](-c3ccc(C(C)C)cc3C(C)C)c(C)cc2c1 +O=C(O)CCn1cc(Cc2ccc(F)cc2)c2cc(NS(=O)(=O)c3ccc(F)cc3)ccc21 +CC(C)Nc1cc(-n2ncc3cc(C#N)cnc32)ncc1C(=O)Nc1cnn(CC(F)F)c1 +O=C(Nc1ccn2ccnc2c1)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +CCOC(=O)C1=C(N)N=C2c3c(-c4ccc(Br)cc4)cn(-c4ccc(S(N)(=O)=O)cc4)c3N=CN2N=C1 +COc1cc(OC)c(C2C(c3ccccc3)C(=O)N2c2ccc(S(N)(=O)=O)cc2)cc1OC +CCCC[S+]([O-])c1sc2nc(-c3nccs3)cc(-c3nccs3)c2c1N +COCCn1cc(C2CCN(Cc3cccc(C(=O)O)c3)CC2)c2ccc(F)cc21 +COc1ccc2c(c1)OCCc1sc(NCC3CCC(NS(C)(=O)=O)CC3)nc1-2 +CCN1CC(O)CC1CN1CCC(c2cc(-c3ccncc3)c(-c3ccc(F)cc3)[nH]2)CC1 +COc1ccc(N2CCN(CCCCn3ncc(=O)n(C)c3=O)CC2)c(C#N)c1 +CCn1ncc(C(C)(C)c2ccccc2)c1C1CCN(CC2CN(C(C(=O)O)C3CCCCC3)CC2c2ccccc2)CC1 +CCCN(C)C(=O)c1cc(N)n2nc(-c3ccc(Br)o3)nc2c1 +O=C(O)CCNc1ncc2c(n1)c(Nc1cccc(Cl)c1)nc1cc(C(=O)O)ccc12 +CC(=O)N1CCN(c2cccc(-c3cc(-c4cnn(C5CC5)c4)c4c(N)ncnn34)c2)C(=O)C1(C)C +O=C(CBr)N(c1ccccc1)S(=O)(=O)c1cc(Cl)sc1Cl +CN1CCN(c2cccc(CCNC(=O)c3cnc(C#N)nc3NCC(C)(C)C)c2)CC1 +CSc1c(F)c(N)c2c(=O)cc(-c3ccc(N)c(F)c3)oc2c1F +O=C(Nc1ccccc1Cl)Nc1cccn(Cc2ccccc2Cl)c1=O +COc1ccc(Cc2nccc3cc(OC)c(OCCF)cc23)cc1Br +CCC(C1CCC(=O)O1)N1C(=O)C(C)(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +Cn1c(=O)c2c(cc(C=Cc3ccc(C#N)cc3)n2C)n(C)c1=O +O=C(NO)C(CCCc1cccc(Oc2ccccc2)c1)P(=O)(O)O +O=c1[nH]nc2[nH]c(CNCCc3cccc(C(F)(F)F)c3)nc3cccc1c32 +N#Cc1ccc(Cc2cc(C(=O)C(=O)Nc3cccnc3)c3ccccn23)cc1 +COc1ccc(-c2nc3n(Cc4ccccc4F)c(C)c(-c4cccc(F)c4)c(=O)n3c2CN(C)CCc2ccccn2)cc1 +O=C(NCCNC(=O)c1cn(-c2ccccc2)nc1C(F)(F)F)c1ccc(-n2cccn2)cc1 +O=C(NCC(O)CN1CCC(Oc2ccc(Cl)c(Cl)c2)CC1)c1c[nH]nc1C1CC1 +O=c1[nH]c(Cc2ccccc2-c2cc[nH]n2)nc2c1cnn2C1CCOCC1 +Oc1ccc(-c2cc(-c3ccoc3)cc(-c3cccc(O)c3)n2)cc1 +COc1ccccc1N1CCN(CCCCCCCn2ncc(Cl)c(N3CCN(CC4COc5ccccc5O4)CC3)c2=O)CC1 +O=S(=O)(Nc1cncc(-c2ccc3ncc(-c4ccccc4)n3c2)c1)c1ccccc1 +[C-]#[N+]c1cnc2c(NCC)nc(Nc3cc(C#N)cc(N4CCC(NCC(C)O)CC4)c3Cl)nn12 +COc1ccc(CNC(C)c2ccc(F)cc2)cc1-c1ccc(C(F)(F)F)cc1 +COCCNc1nc(-c2ccc(C3(O)CCC3)cc2)cc2ncn(C)c(=O)c12 +OCC1C(O)C(O)C(O)CN1CCCCCOCc1cc2ccccc2c2ccccc12 +COc1c(C(=O)NCCN2CCCC2)n(C)c2c1c(=O)n(CC(=O)c1ccccc1)c1ccccc21 +CCCOC(=O)N1CCC(N(C(=O)c2ccc(-c3cnco3)cc2)C2CC2)CC1 +O=C(NC1CCN(Cc2ccc(C(F)(F)F)cc2)CC1)c1ccc2ccccc2c1 +CC(C)(C)c1cc(NC(=O)Cc2cccc(Oc3ccc4nccn4n3)c2)no1 +CC(=O)N1CCN(c2cccc(-c3cc(-c4ccnn4CC(F)(F)F)c4c(N)ncnn34)c2)C(=O)C1(C)C +Cc1cccc(Nc2ccccc2C(=O)NCCCCCC(=O)NCCCCCCNc2c3c(nc4cc(Cl)ccc24)CCCC3)c1C +N#Cc1ccc2ncc(C#N)c(CCC34CCC(NCc5ccc6c(n5)NC(=O)CO6)(CC3)CO4)c2n1 +Cc1ccc(Oc2ccc3nc(NC(=O)C4CC4)nn3c2)cc1NC(=O)CC(C)C +O=C(NCC(c1cccnc1)N1CCN(c2ccc(F)cc2)CC1)c1ccco1 +COc1ccc(CN2CCN(Cc3ccccc3)C(CO)C2)cc1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1OC1Cc2ccccc2C1)c1ccc(NS(C)(=O)=O)c(F)c1 +CNC(=O)c1cc(Cl)cc(C)c1NC(=O)c1cc(C(F)(F)F)nn1-c1ncccc1Cl +CC(C)CCN(CCC(C)C)CC(O)Cn1c2ccc(Cl)cc2c2cc(Cl)ccc21 +O=C(O)Cc1c2n(c3ccccc13)CC(N(Cc1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1)CC2 +CCCCOC(=O)c1ccc(NC(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1ncn(-c2ccc(Nc3ncc4cccc(-c5nccs5)c4n3)cc2)n1 +CC(C)COP(=O)(CCCCC1(C(=O)NCC(F)(F)F)c2ccccc2-c2ccccc21)OCC(C)C +Cc1ccccc1C(C)(C)CC(O)(Cn1ccc(=O)c2ccccc21)C(F)(F)F +CC(=O)OCC1Cc2ccccc2CN1C(=O)C(N)Cc1c(C)cc(O)cc1C +CCCNC(=O)Nc1cccc(-c2ccc(CC(NC(N)=O)C(=O)O)cc2)c1 +Clc1ccc(-n2cc3c(n2)c(NC2CCCCC2)nc2ccccc23)cc1 +O=C(O)c1ccc(S(=O)(=O)N(Cc2ccc(F)c(C(F)(F)F)c2)c2sc3ccccc3c2C2CCC2)cc1 +Cc1ccc(F)c(CNc2ccc(C(=O)Nc3onc(C)c3C)nn2)c1F +Cn1c(=S)c2nc(C3CCCC3)[nH]c2n(C)c1=O +O=c1ccc(OCCCN2CCN(c3nsc4ccccc34)CC2)nn1-c1ccc(Cl)c(Cl)c1 +COc1ccccc1N1CCN(CC2COC3(CCN(C(C)=O)CC3)O2)CC1 +COCC1CCC(C)N1c1cc(NC(C)=O)nc(-n2nc(C)cc2C)n1 +CCN1Cc2ccc(NC(=O)c3ccc(C(=O)N4CCC(C5CCCN5)CC4)c(Nc4ccccc4)c3)cc2C1 +O=C(Nc1ccc(-c2nnc(NCCCCN3CCCCC3)o2)cc1)C1CCCCC1 +CCOC1CN(Cc2ccc(C#Cc3ccc(C(=O)N(C)C(C(=O)NC)C(=O)NO)cc3)cc2F)C1 +CC1=C(C(=O)Nc2ccc3[nH]ncc3c2)C(c2ccc(F)c(C(=O)NCCc3c(C)cccc3C)c2)NC(=O)N1 +O=C1c2ccccc2CC1CCC1CCN(Cc2ccccc2)CC1 +CC(C)CC(NC(=O)CNc1cccc(Oc2ccccc2)c1)C(=O)NC1CC(=O)OC1O +CC(C)CCNC(=O)C1CCN(Cc2cccc(NC(=O)c3cccc(C(F)(F)F)n3)c2)CC1 +c1ccc(-c2cc[n+](Cc3cccc(-c4cccc(C[n+]5ccc(-c6ccccc6)cc5)c4)c3)cc2)cc1 +O=C(NC1CCCc2c1[nH]c1ccc(Cl)cc21)c1ccccc1F +Cc1nccc(-n2c(Nc3cccc(O)c3)nc3ccccc32)n1 +Nc1nc(-c2cc(=O)oc3cc(Sc4ncc(C(O)(C(F)(F)F)C(F)(F)F)s4)ccc23)cs1 +OCc1cc(OCC(O)CNC2CCN(c3ncnc4sccc34)CC2)ccc1O +CC(=O)NC(C)c1ccc(OC2CCN(c3ccc(Oc4cnccn4)cc3)C2)cc1 +O=C(NCc1ccc(Br)cc1)Nc1ccc(-c2ccnc3[nH]cnc23)cc1 +COCCOC(=O)N1CC(CC#N)(n2cc(C(N)=O)c(Nc3ccccc3)n2)C1 +C=C(c1ccccc1)C12CCCC1CC(CCCCCC)=C2CCCC +CCOC(=O)Cc1cccc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)c1 +CCCN1CCN(c2cc(-c3ccc(Sc4ccccc4OC)c(C(F)(F)F)c3)ccn2)CC1 +O=c1cc(-c2ccc(OC3CCN(C4CCC4)CC3)cc2)cn[nH]1 +COc1ccc(C2CC2COc2cc(NCc3ncccc3C)c(=O)n(C)n2)nc1 +C=CC(=O)N1CCCC(Nc2ncnc(N)c2C(=O)c2ccc(Oc3ccccc3)cc2)C1 +CCN(CC)CCCCNc1cc2nc(N)c(-c3c(Cl)cccc3Cl)cc2cn1 +CN1CCC(NC(=O)C2CCC3CN2C(=O)N3OS(=O)(=O)O)CC1 +O=C(Nc1cccc(CN2CCC(C(=O)NC3CCCCC3)CC2)c1)c1ccccn1 +O=C(NO)C1(NS(=O)(=O)c2ccc(Oc3ccc(Cl)cc3)cc2)CC2CCC(C1)O2 +CN(C)c1ccc(C=C2C(=O)N(Cc3ccccc3)c3ncccc32)cc1 +CC(=O)NC(C(=O)O)C1CCC(=C2SCCCS2)C1 +O=C1COC2(CCN(S(=O)(=O)c3ccc(-c4cccc5cnccc45)cc3)CC2)CN1C1CC1 +CC(C)COc1ccc(-n2cc(C(=O)O)cn2)cc1C#N +COc1ccc(Br)cc1Cn1c(C(=O)NCCCO)cc2cc(C#N)ccc21 +COc1ccccc1N1CCN(CCC(=O)NC2CCc3c(cccc3OC)C2)CC1 +CCC(C)C(N)C(=O)NS(=O)(=O)OCC1OC(c2nc(-c3ccccc3OC)cs2)C(O)C1O +Cc1noc(Cc2cccc(CC(=O)Nc3ccc(CCCCc4nnc(NC(=O)Cc5ccccc5)s4)nn3)c2)n1 +CCOC1CCC(CS)(C(=O)NC(Cc2ccccc2)C(=O)NC2CCCC2)CC1 +CCN1CC(C)(C)Oc2nc(N3CC4CCC(C3)O4)nc(-c3ccc(NC(=O)Nc4cccc(OC)c4)cc3)c2C1=O +COC1(C(=N)C=C(O)OCc2ccc3ccccc3c2)CCOCC1 +CN(C)C(=O)C(c1ccc(-c2ccc(F)cc2F)cc1)C(N)C(=O)N1CCC(F)C1 +O=C(C=Cc1ccccc1)NC1COC(=O)CCCC(CN2CCOCC2)OC(=O)C(O)C(CC2CCCCC2)NC1=O +c1cc2nc3ccc(N4CCCCC4)cc3[o+]c2cc1N1CCCCC1 +CNc1nc2cc3c(cc2[nH]1)N(Cc1ccc(S(=O)(=O)c2ccccc2)cc1)CCC3 +CC(OC1OCCN(Cc2n[nH]nc2CN2CCC2)C1c1ccc(F)cc1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CC(=O)NCCOc1ccc(C(=O)N2CCC(N3C(=O)CCc4ccccc43)CC2)cc1 +O=C(O)CCc1cc(Br)c(OCC2CCCCC2)c(Br)c1 +c1cc(COc2ccc(-c3nc4ccccc4[nH]3)cc2)cc(COc2ccc(-c3nc4ccccc4[nH]3)cc2)c1 +COc1ccc(CC(=O)NC(NC(=S)Nc2ccccc2C)C(Cl)(Cl)Cl)cc1OC +CNS(=O)(=O)Nc1cccc(Cc2c(C)c3ccc(Oc4ncccn4)cc3oc2=O)c1 +CC(=O)c1cccc(-c2cc3nc(N)nc(N)c3cc2C)c1 +COc1cccc(OC)c1C1CCC(=O)N1Cc1cccc(-n2cccn2)c1 +CC(N=C1C=C(O)c2cccnc2C1=O)C(O)c1ccccc1 +CN1CCCC(Nc2ncnc3[nH]cc(-c4cccc(C#N)c4)c23)C1 +CC(C)C(=O)Nc1ccc2nn(-c3ccc(Cl)cc3)nc2c1 +COc1ccc(CCN2C(=O)N(NS(C)(=O)=O)CC2c2ccc(OC(C)C)cc2)cc1 +Cc1ccc(C(C#N)=C(c2ccc(O)cc2)c2ccc(O)cc2)cc1 +N#Cc1ccc(NCC(F)(F)c2ccccn2)[n+]([O-])c1CC(=O)NCc1cc(Cl)ccc1-n1cnnn1 +O=C(C=Cc1ccc(CNCCc2c(-c3cccs3)[nH]c3ccccc23)cc1)NO +CC(C)CC1NC(=O)C2Cc3c([nH]c4ccccc34)CN2C1=O +CCc1ncc(C(CNC(=O)c2c(Cl)cccc2Cl)N2CCC(F)(F)CC2)cn1 +Cc1cccc2nc(N3CCN(Cc4ccc(Br)s4)CC3)c3cccn3c12 +COc1ncc(-c2cc(NC(=O)c3ccnc(C(C)(C)C#N)c3)ccc2C)cc1N1CCOCC1 +COCCN(C)CC1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +O=C(Cc1ccc(Cl)cc1Cl)NC1COc2cnc(Cl)cc21 +C#CCC(C(=O)NC(C(=O)NC(CC(=O)O)C(=O)CSCc1ccccc1)C(C)C)c1cc(Br)ccc1OC +O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(c2ccccn2)CC1 +Cc1cc2c(OCC(O)CN3CCC(c4cc5cc(F)ccc5s4)CC3)cccc2[nH]1 +C=CCN1CCC23c4c5ccc(O)c4OC2C(=NNC(=O)c2ccccc2)CCC3(O)C1C5 +Cc1ccc(Nc2ccc(-c3cc(OC(C)C)ccc3F)nc2)c(C(=O)O)c1 +CCNC(=O)Nc1nc2cc(-c3cccnc3)cc(-c3ccc(O)cc3)n2n1 +N#Cc1cccc(NC(=O)Nc2ccc(C3CNCCO3)cc2Cl)c1 +N=C(N)N1CCCC1Cc1nc(-c2ccc(Nc3nc(-c4ccc(F)c(C(F)(F)F)c4)cs3)cc2)no1 +NC(C(=O)N1CCC(F)C1)C1CCC(NC(=O)c2ccccc2C(F)(F)F)CC1 +CCCCCCCCCCCCCCCCCCSCC(COC)COP(=O)([O-])OCC[N+]1(C)CCCCC1 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+CN(CCNc1ccnc2cc(Cl)ccc12)CCN1C(=O)C=C(OCc2ccccc2)C1(O)Cc1ccccc1 +O=C(O)CCNc1ccc(-c2nc3ccc(C4(c5ccccc5)CC4)nc3s2)c(F)c1 +CC(C)(C)CCN1CCCc2cc(Oc3ccc(C(N)=O)cn3)ccc2C1 +NC(=O)C1(c2ccccc2CCc2nc(Nc3cncnc3)ncc2Cl)CC1 +CN(C)c1nc(NN=Cc2ccc([N+](=O)[O-])o2)nc(N(C)C)n1 +COc1cc(C(F)(F)F)ccc1-c1nccc2cc(S(=O)(=O)Nc3nccs3)ccc12 +O=S(=O)(NC1CCN(CCOc2ccccc2-c2ccccc2)CC1)c1cccc2ncccc12 +CN1CCN(c2nc(NCc3ccccc3)c3c(n2)-c2ccccc2CC3)CC1 +CCC(=O)N(CCN1C2CCC1CC(c1cccc(O)c1)C2)CC1CCCCC1 +CC(C)(NC(=O)c1cc2c(n(CC3CCCCC3)c1=O)CCCCCC2)C(=O)N1CCC(C(N)=O)CC1 +COc1cc(S(=O)(=O)c2cccc(-n3cccn3)c2)cc2c3c(n(C)c12)CC1CCC3N1 +Cc1ccc(Br)c(C(=O)Nc2ccc(Cn3nc(C)c(CC(=O)O)c3C)cc2)c1 +COCCOC1CCN(c2cc(C)c3nc(-c4c(NCC(O)c5cccc(Cl)c5)cc[nH]c4=O)[nH]c3c2)CC1 +CN(C)C(=O)c1sc2c(c(N3CCC(COCCN4CCCC4)CC3)nn2C)c1-c1ccccc1 +CSc1ncc2cc(-c3ccccc3)c(-c3ccc(CN4CCC(C(=O)Nc5ccncc5)CC4)cc3)nc2n1 +O=C(O)Cc1sc(C(c2ccc(F)cc2)c2ccc(F)cc2)nc1-c1ccnc(Cl)c1 +COc1ccccc1C=CC(=O)NCCn1c(C)cc2ccccc21 +CNC(=O)CC1COc2cc(Cl)ccc2N1C(=O)c1ccc2c(c1)NC(=O)CO2 +Cc1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1C#Cc1ccc(N)nc1 +O=C(Nc1ccsc1-c1ccccc1)OC1CN2CCC1CC2 +COC(=O)CN1C(=O)C2(CCN(CC3CCCCCC3)CC2)c2ccccc21 +COc1cc(NC(=O)C=Cc2cccc(C)c2)ccc1-c1cnco1 +COc1ccc2c(OCc3nnc4ccc(-c5cc(C)no5)cn34)ccnc2c1 +O=C(Nc1ccc(Cl)cc1C(=O)Nc1ccc(Cl)cn1)c1ccc(-c2ccccc2N2CCCCC2)cc1 +CC1CN(C(c2cccc(O)c2)c2ccc3c(c2)CN(CC(=O)O)C3)C(C)CN1Cc1ccccc1 +N#Cc1ccc(C(=O)N2CCC3(CC2)Nc2cc(Cl)ccc2-n2cccc23)cc1 +O=C(Nc1c(Cl)cncc1Cl)c1ccc(OC(F)F)c(OCCCSC(CCO)C(=O)O)c1 +O=C(Cn1nc(-c2ccc(Cl)cc2Cl)c(-c2ccc(Cl)cc2Cl)n1)NCc1ccc(F)cc1 +Cc1ccc2c(-c3nnc(SCCCN4CC5CC5(c5ccc(C(F)(F)F)cc5)C4)n3C)cccc2n1 +CC(C)(Cc1ccc(-c2cccc(-n3cc(C(=O)NC4CC4)c(=O)c4cccnc43)c2)cc1)C(=O)O +CCc1ccc(-n2nc(C(F)(F)F)c3c2C(=O)N(c2ccc(-c4ccccc4CN(C)C)cc2)CC3)cc1 +Cc1ccccc1NC(=O)Nc1ccc(CC(=O)Nc2cccc(NC(=O)NCC(=O)O)c2)cc1 +COc1cc(C)c2c(Oc3cccc(C(F)(F)F)c3)c(OC)cc(NC(C)CCCN)c2n1 +CC(=O)Nc1ccn2c(-c3ccccc3)c(-c3ccc(C4(N)CCC4)cc3)nc2c1 +Cc1cc(Nc2nc3ccc(C(=O)Nc4c(C)cccc4Cl)cc3s2)ncn1 +CCCCNC(=O)C1CCN(CC(=O)Nc2cc(N)c(C#N)c(OCC)n2)CC1 +CCCCC(CC(CCc1ccc(-c2ccc(C(=O)OC)cc2)cc1)C(=O)NC(C(=O)NC)C(C)(C)C)C(=O)O +Cc1c(I)c(=O)n(C2CCCC2)c2nc(Nc3ccc(N4CCNCC4)cc3)ncc12 +O=C(CCCCCCCCCCCCc1ccc(C(F)(F)F)cc1)Nc1ccc2nc([N+]34CCC(CC3)CC4)ccc2c1 +CCOC(=O)c1cnc2c(cnn2CC(Cl)c2ccccc2)c1NCCc1ccccc1Cl +Cc1c(OC2CCN(CC3CCN(C(Cc4ccccc4)C(=O)O)CC3)CC2)ccc(Cl)c1Cl +COc1ccc2c(c1)CCCC2CCCN1CCCC(C)(C)C1 +OCc1cc(N2CCCC2)ccc1-c1nc2c(s1)C(O)CNC2 +CN1CCN(C(CN2CCN(CCCCc3cccc4ccccc34)CC2)c2ccc(Br)cc2)CC1 +CC(=O)NC(C)c1ccc(OC2CCN(c3ccnc(OC4CCOC4)c3)C2)cc1 +c1ccc2c(c1)COC21CCN(CCCCc2cn(-c3nccs3)c3ccccc23)CC1 +CNC(=O)C(NC(=O)C(CC(C)C)C(NS(=O)(=O)CCc1ccncc1)C(=O)NO)C(C)(C)C +CCC(=O)Nc1nc2cc(C3(O)c4ccccc4C(=O)N3Cc3ccccc3)ccc2[nH]1 +CN(C)c1ccc(C(O)c2ccc(N(C)C)c3ccccc23)cc1 +CC(=O)NC(C)c1ccc(OC2CCN(c3cccc(N4CCOC(C)(C)C4)n3)C2)cc1 +CNC1c2cc3c(ccn3S(=O)(=O)c3ccccc3)cc2C1CCO +CC(C)c1cccc(C(C)C)c1NC(=O)NCCCCCSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1 +COc1ccc(N(C)c2nc(C)nc3ccc(N(C)C)cc23)cc1 +N#Cc1cc2c(F)c(F)cc(-c3ccc(OCc4cccc(C(=O)N5CCCC5C(=O)O)c4)cc3)c2o1 +CC1(C)C(=O)N(c2ccc(C#N)c(C(F)(F)F)c2)C(=O)N1CCc1cccc(I)c1 +N#CC(=C(c1ccccc1)c1ccc(O)cc1)c1ccc(O)cc1 +CCC12CC(C)(O)C(O)(c3ccccc3)CC1C=Cc1cc(O)ccc12 +CCC(NC(N)=O)C1CCC(N2CC(NC(=O)CNc3ncnc4ccc(C(F)(F)F)cc34)C2)CC1 +COc1cc(-c2ccc(Cl)c(C)c2)c(F)cc1-n1c(=O)cnc2cc(S(=O)(=O)Nc3ccon3)ccc21 +N#CCC1(n2cc(-c3c(F)cnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)c3ccc(O)c(F)c3)CC2)C1 +O=C(NC(Cc1c[nH]c2ccccc12)C(=O)O)c1ccc2c(c1)nc(-c1ccoc1)n2C1CCCCC1 +COc1cnc(CC#N)cc1-c1nc2c(n1C(C)C)C(c1ccc(Cl)cc1)N(c1cccc(Cl)c1F)C2=O +CC(O)CC(c1ccccc1)c1c(O)oc2ccccc2c1=O +CC(=CC(=O)Nc1ccccc1OCCCC(=O)O)c1ccc2c(ccn2C(c2ccccc2)c2cccnc2)c1 +Cc1cccc(-c2nn3c(c2-c2ccnc4ccc(Br)cc24)CCC3)n1 +CCCN(CCC)S(=O)(=O)c1ccc(C(=O)NC)cc1 +CN1CCC(c2c[nH]c3ccc(NS(=O)(=O)c4cccc5c(Cl)cccc45)cc23)CC1 +COc1cc(N2C(=O)c3ccccc3C2=O)ccc1NC(=O)c1occc1C +Cc1onc(-c2ccc(Cl)cc2)c1COc1ccc(C(=O)NC(C)C)cn1 +O=C(Nc1cn2nc(-c3cn(C4CC4)nc3-c3ccc(F)cc3)ccc2n1)c1ccnc(F)c1 +CNC(C)C(=O)NC1C(=O)N(Cc2cccc3c2cc(C#N)n3-c2ccccc2C#N)c2ccccc2SC1(C)C +C#CCN(Cc1ccc2cccc(O)c2n1)C(C#N)CC1CCN(Cc2ccccc2)CC1 +CCN(CC)Cc1cccc2c1-c1nc(N)nc(-c3ccccc3)c1C2=O +CC(C)CC(NC(=O)c1cccs1)C(=O)NC1COCC1=O +CC1C2Cc3cc(N)c(C(N)=O)cc3C1(C)CCN2CC1CC1 +COc1cc(-c2cccc(C#N)c2)ccc1-n1c(=O)ccc2cc(S(=O)(=O)Nc3ccon3)ccc21 +CC(C)c1c(Oc2ccccc2)cc(CCc2ccccc2)[nH]c1=O +CS(=O)(=O)N1CCC(c2nccnc2Oc2ccc(Nc3ccccn3)cc2)CC1 +CN(C)C1CCN(c2ccc(Nc3c(S(C)(=O)=O)cnc4ccc(-c5cc(F)c(O)c(Cl)c5)cc34)cn2)C1 +Cc1cc(Nc2cc(C(F)(F)F)ccn2)nc(-c2ccc(NC3CCN(C(=O)CCCN4CCCC4=O)CC3)nc2)c1 +Nc1ncnc(N2CCC(c3nc(-c4ccnc(C(F)(F)F)c4)cn3CCN3CCC3)CC2)c1Br +CSc1c(C2=C(c3cn(C)c4ccccc34)C(=O)NC2=O)c2ccccc2n1C +CS(=O)(=O)Nc1cc(C2C([N+](=O)[O-])C(c3ccccc3Br)CCN2Cc2cccnc2)ccc1O +O=C(Nc1c[nH]nc1C(=O)Nc1ccc(F)cc1)c1ccccc1 +OCC1CCC(Nc2cc(-c3cccc(NCc4cccc(F)c4)n3)c(Cl)cn2)C1 +Cc1noc(C2CCCN(Cc3ccc(-c4nnc5n4-c4cccnc4Nc4ccccc4-5)cc3)C2)n1 +CC(C)Oc1ccccc1N1CCN(Cc2cccc(CNc3ccc(F)cc3)c2)CC1 +c1ccc2nc(N3CCC(Oc4nccnc4-c4ccncc4)CC3)ccc2c1 +COc1ccc(C(CC(=O)O)Cc2csc(CCCCNc3cc(N4CCSCC4)ccn3)n2)cn1 +O=C(NCc1ccncc1)c1sc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)nc1C(F)(F)F +NC1CCCCC1NS(=O)(=O)c1ccc(-c2ccc(CSc3nc4c(c(=O)[nH]3)CCC4)cc2)cc1 +Nc1nccn2c(C3CCC3)nc(-c3cccc(OCc4ccc(Cl)cc4)c3)c12 +CCC(=O)c1ccc(OCC(O)CN2CCN(c3ccccc3C)CC2)cc1 +COc1cncc(-c2ccc3[nH]nc(-c4cc(N5CCOCC5)ncn4)c3c2)n1 +N#CC(Cc1ccc(-c2ccc3c(c2)COC3=O)cc1)NC(=O)C1NC2CCC1C2 +CC(NC(=O)c1cncc2cccnc12)c1cc2cccc(Cl)c2c(=O)n1-c1ccccc1 +CCCCCC(=O)c1ccc(OCCCN2CCN(C(=O)C(N)Cc3ccncc3)CC2)cc1 +CC1(O)CC(N)(c2ccc(-c3nc4n(c3-c3ccccc3)COc3cccnc3-4)cc2)C1 +NS(=O)(=O)c1ccc(-c2ccc(NC(=O)C3CN4CCC3CC4)cc2)cc1 +CN(CCCCNC(=O)c1cc2ccccc2o1)C1Cc2cccc3[nH]c(=O)n(c23)C1 +COc1cc(N2CCN(C(=O)Cn3nc(C(F)(F)F)c(Cl)c3C)C(CO)C2)ccc1Cl +Nc1ccc(-c2ccc(Cl)cc2)n[n+]1CCCC(=O)O +COc1cccc(F)c1CN1CC(NC(=O)c2ccc3[nH]nc(-c4ccc5nc(C)sc5c4)c3c2)CCC1C(N)=O +Cc1c(Cc2ccccc2)nc(SCCCc2ccccc2)[nH]c1=O +NS(=O)(=O)c1ccc(NC(=O)NCCN2CCN(Cc3ccccc3)CC2)cc1 +CC1(C(=O)N2CCOCC2)COC(c2nc(-c3ccc(F)cc3)c(-c3ccnc(NCC4CC4)n3)[nH]2)OC1 +CC(C)c1cccc(C(C)C)c1NC(=O)NC1=NN(CCCCCCCCCCCO)NN1 +CC(NCC(O)C(Cc1ccccc1)NC(=O)c1ccc(N(C)c2ccncc2)cc1)c1ccccc1 +O=C(c1cncc2ccccc12)N1C2CCC1C(Nc1cnc(C(F)(F)F)cn1)C2 +OC1CCN(Cc2ccc(F)cc2)CC1N1CCC2(CCc3ccccc32)CC1 +CCCN(c1ccccc1N1CCN(C(=O)C(Cc2ccc(Cl)cc2)NC(=O)C2Cc3ccccc3CN2)CC1)S(C)(=O)=O +O=C(Cc1ccc(-c2ccccc2)cc1)NC1CCN(Cc2ccc3c(c2)OCO3)CC1 +CNC(=O)C(NC(=O)c1ccc(-c2cccc(CNC(=O)c3occc3C)c2)o1)C1CCCCC1 +c1nc(CC2CCN(CCCOc3ccc(N4CCNCC4)cc3)CC2)c[nH]1 +COc1cccc2c1CC1CC(C(=O)N3CCN(c4ccccc4C#N)CC3)CN(C)C1C2 +Cn1cnc(C(=O)N(Cc2cccc(Cl)c2)C2CCC(N)CC2)c1 +COc1cc(C=C2SC(=S)NC2=O)ccc1OCc1ccccc1 +COc1cc(CCNCc2cccc3ccoc23)c(OC)cc1Br +NC(=O)c1cncc(OCc2cccc(NC(=O)c3ccc(-c4cccs4)nc3)c2)c1 +OC1CCCN(Cc2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nc2)C1 +c1cc(-c2cnn3nc(N4CCOCC4)ccc23)nc(NC2CC2)n1 +CS(=O)(=O)NCC1CC2CCCCC2N1C(=O)CC(N)Cc1cc(F)c(F)cc1F +CCc1nc(N)nc(N)c1-c1ccc2c(c1)N(CCNC(C)=O)C(=O)C(C)(C(F)(F)F)O2 +c1ccc(Nc2ccc(Oc3ncccc3-c3ccsc3)cc2)nc1 +CCN(CC)CCCOc1ccccc2c(C=C3C(=O)Nc4ccc(F)cc43)cc(C)c1-2 +COc1cc(C2CCNCC2)ccc1Nc1nc(Cc2cccc(Cl)c2Cl)n2cnnc2c1C(N)=O +O=C(NO)C1CCS(=O)(=O)N1c1ccc(-c2ccccc2)cc1 +COc1cnn(C)c(=O)c1-c1ccc(CC(NC(=O)N(c2ccccc2)C(C)C)C(=O)O)cc1 +CCCOc1ccc(-c2csc(C)n2)cc1-c1nc2c(c(C)nn2C)c(=O)[nH]1 +O=C(O)C(Cc1ccc(N2CCN(c3cnccn3)CC2)cc1)NC(=O)C1CCCN1S(=O)(=O)c1ccccc1 +CCCCC(C=O)NC(=O)OC(C)(C)Cc1ccc(OC)cc1 +CCCCC(=O)N(Cc1ccc2ccccc2c1)c1cc(-c2nnn[nH]2)ccc1F +O=C(c1cccc(F)c1-c1ncccn1)N1CCC2CN(c3cc(C(F)(F)F)ccn3)C2C1 +NC(=O)c1cn2c(n1)-c1cc(C#CC(O)(CF)CF)c(F)cc1OCC2 +COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cccc(C(C)(C)C)c4)c3)c2cc1OC +CCCC(=O)NC(c1ccccc1Cl)c1ccc2cccnc2c1O +CCC(NC(=O)c1cc(C(=O)N2CCCC2C)n2c1COCC2)c1ccc(Cl)s1 +Cc1cc(C2CCN(C)CC2)cc2[nH]c(-c3c(NCCn4cc(Cl)cn4)cc[nH]c3=O)nc12 +COc1cc(C(=O)NCc2cccc(-c3ccccc3)c2)ccc1-c1cn[nH]c1 +CCOC(=O)CC1(c2ccccc2)C(=O)Nc2ccc(-c3c(C)noc3C)cc21 +Cc1cccc(C(CO)NC(=O)c2ccc(-c3cc(-c4cn(C)nc4C)cnc3N)cc2F)c1 +NC(=O)N1CCCc2c1ncc(-c1cncc(C3(O)CCOCC3)c1)c2F +O=C(Nc1ccc(N2CCOCC2)cc1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 +Cc1c(C(F)F)nn(-c2ccc(S(C)(=O)=O)cn2)c1-c1ccccc1 +CN1CCC(c2c(O)cc(O)c3c(=O)cc(SC(C)(C)C)oc23)C(O)C1 +CCCc1c(OCCCOc2ccc3c(c2)CCC3CC(=O)O)ccc2c1ccn2C +CC(=NOCC#N)c1ccc(Sc2cc(F)cc(C3CCOCC3)c2)cc1 +O=C(Nc1ccc(OCC(F)(F)C(F)F)c(C(F)(F)F)c1)c1ccccc1O +N#Cc1cnn2c(Nc3ccc4c(c3)CCC(=O)N4)cc(N3CCCC3CO)nc12 +CC(C)(O)C(F)CNC(=O)c1cnc(-n2ccc3cc(C#N)cnc32)cc1NCC1COC1 +CN1CCN(Cc2ccc(C(=O)NN(CCC3CCCC3)c3nc(C#N)ncc3Br)cc2)CC1 +CCN(Cc1cc([N+](=O)[O-])cc2nc(O)c(O)nc12)CP(=O)(O)O +Cc1ccc2c3c(nn2c1)CCC(NC(=O)c1c(Cl)cc(-n2cnc(C)n2)cc1Cl)(c1cccc(F)c1)C3 +Cc1ccc(-n2c(C)nnc2SCC(=O)Nc2ccccc2C#N)cc1 +O=C(Nc1ccc(-c2nnc(NCCCN3CCCCC3)o2)cc1)c1c(F)cccc1F +CN1CCN(CCCNC(=O)c2c(O)c3ncc(Cc4ccc(F)cc4)cc3[nH]c2=O)CC1 +CC(C)(C)c1nnc(-c2nn(-c3ccc(Cl)cc3Cl)c(-c3ccc(Cl)cc3)c2COc2ccccn2)o1 +O=C(NC1(C(F)(F)F)CCC1)c1nn(-c2ccc(Cl)cc2Cl)c(-c2ccc(Br)cc2)c1Cn1cncn1 +Cc1nc(N2CCC(N3CCCC3C)C2)ccc1NC(=O)c1cccc2ccccc12 +Cc1cc(N2CC3CN(C(=O)c4ccccc4-n4nccn4)CC3C2)nc(C)n1 +CN(CCO)c1ccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)cc1-c1cncs1 +N=C(N)c1ccc2[nH]c(-c3cc(C(CC(=O)O)C(=O)O)cc(-c4cccc(CN)c4)c3O)nc2c1 +CC(C)NCC1(O)CN(C(=O)c2ccc(F)c(F)c2Nc2ccc(I)cc2F)C1 +CCOC(=O)N1CCC(=C2c3ccc(Cl)cc3CCc3cccnc32)CC1 +CNC(=O)C(Cc1ccc2ccccc2c1)N1CCN(C(=O)C(N)Cc2ccc(F)cc2)C(CCN(C)C)C1=O +CCC(CC)(Cc1ccc(C(=O)Oc2ccc(C(=N)N)cc2F)s1)C(=O)Nc1cc(C(=O)O)cc(C(=O)O)c1 +FC(F)(F)c1cccc(Nc2ncnc3ccc(-c4cncs4)cc23)c1 +C=CCN(C)CCCCCCOc1ccc2c(-c3ccc(Br)cc3)csc2c1 +Cc1ccc(C(=O)N2CCC(F)(c3ccc(C#N)cc3)CC2)cc1-c1[nH]c(C2CC2)nc1Cl +O=C(Nc1ncccn1)C1=C(O)CCn2c1nc1ccccc12 +CCOC(=O)C1C2NC(CC(=O)O)C(=O)CNC(=O)C(CCCNC(=N)N)NC(=O)C(C(C)C)NC(=O)C21 +Cc1nc(C2CC3CSC(N)=NC3(c3ccc(F)cc3F)CO2)co1 +Cc1nnc2c(NC3CCN(S(=O)(=O)C4CCNC4)CC3)cc(N(C)Cc3ccccc3)nn12 +O=S1(=O)NCCCNc2nc(ncc2Br)Nc2cccc1c2 +CN1CCN(C(=O)NC23CC4CC(CC(C4)C2)C3)CC1 +O=C(Cc1ccc2cccnc2c1)Nc1cncc(C(=O)c2cn(C(CO)CO)c3ncncc23)c1 +CC1(c2ccc(OCCN3CCCC3)cc2)c2ccc(O)cc2CCN1c1ccc(Cl)cc1 +CC(Nc1ncnc2c(C(N)=O)cccc12)c1cccc(NC(=O)c2ccc(C(F)(F)F)cc2F)c1 +COc1ccc(CCN2C=CC=C3C2=Nc2ccccc2N(C)S3(=O)=O)cc1 +O=c1ccc2ncc(F)c3c2n1CC3(O)CN1CCC(NCc2cc3c(cn2)OCCO3)CC1 +CNC(=O)Cn1c(=O)n(C2CCN(C3CCC4CCCCC4C3)CC2)c2ccccc21 +COCCN1CCCC(c2cc3c(-c4cc(F)ccc4OC)ccnc3[nH]2)C1 +NC1CC1NC(=O)c1cnc(Oc2ccc3c(c2)CCC(c2ccccc2)O3)s1 +Cc1cccc(N2CCN(CCCNC(=O)c3cc(-c4ccc(Cl)cc4)[nH]c3C)CC2)c1C +CCCCCCCCCCCCCCN(C)S(=O)(=O)NC(=O)Nc1c(C(C)C)cccc1C(C)C +Cn1c(=O)[nH]c2nc(-c3ccccc3)n(C)c2c1=O +COc1cc(Cc2c(C)nc(N)nc2N)cc(OC)c1OC +COc1ccc(Oc2c(-c3ccc(S(C)(=O)=O)cc3)oc(C)cc2=O)c(Cl)c1 +CC(C)N1CCN(c2ccc(C3c4ccc(O)cc4CCN3c3cccc(O)c3)cc2)CC1 +Cc1ccncc1NC(=O)N1CCc2nc(-c3ccc(O)nc3)nc(OC(C)C)c2C1 +COc1ccc2c(c1)[nH]c1c3ccncc3cc(CN(C)C)c21 +COCC(=O)Nc1cccc(NC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Br)c(C)nc34)c2Cl)c1 +COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccnc(NCCO)c2c(=O)n1Cc1ccnc(C)c1 +CC1CCC(CC(CC(=O)N2CCOCC2)C(=O)NC2(C#N)CCN(C3CCCCC3)C2)CC1 +COc1ccc(CN2C=NC3CN(C(=O)C(c4ccccc4)c4ccccc4)C(C(=O)O)CC32)cc1C +CC(C)(C)n1cc2c(n1)C(=O)NC1(CCN(C(=O)c3ccc4c(Cl)c[nH]c4c3)CC1)C2 +Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3cc(Cl)ncn3)sc2c1 +O=C(Cc1ccccc1)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3CO)s2)s1 +COc1c(O)ccc2c1-c1ccc3c(c1C(=Cc1cccc(C(F)(F)F)c1C)O2)C(C)=CC(C)(C)N3 +COc1ccc2c(c1)C(=Cc1cnc[nH]1)C(=O)N2 +CC1(C)CCC(C)(C)c2cc3c(cc21)CCc1c(-c2ccc(C(=O)O)cc2)nn(Cc2cccnc2)c1-3 +Cn1cncc1C(O)C1=Cc2cccnc2C(N2CCN(C(=O)NCc3ccccc3)CC2)c2ccc(Cl)cc21 +CCc1c(CN2CCCc3ccccc32)nc(SCC(=O)c2ccc(OC)cc2)[nH]c1=O +Cc1cc2n[nH]c(=O)n2c2cc(-c3ccc(CO)cc3)ccc12 +c1cc2c3cnc(Nc4ccc(N5CCC(N6CCOCC6)CC5)nn4)nc3n(C3CCCC3)c2cn1 +O=C1CC(NC(=O)C2CNCC3CCCCC(NC(=O)c4nccc5ccccc45)C(=O)N32)C(O)O1 +CN1CCN(c2ccc(-c3ccnc(Nc4ccc5ncsc5c4)n3)cc2)CC1 +Cc1c(NC(c2nnc(-c3ccc(C#N)cc3)o2)C(C)O)ccc(C#N)c1Cl +CCC1CCCC(NC(=O)C=Cc2cc(Cl)ccc2-n2cnnn2)c2nc(c[nH]2)-c2ccc(NC(=O)OC)cc2NC1=O +N#Cc1cccc(-c2c[nH]c3ncnc(N4CCC(c5ncc[nH]5)CC4)c23)c1 +N#Cc1ccc(C2CCN(CCc3cnn(-c4nccc5c(=O)[nH]cnc45)c3)CC2)cc1 +CS(=O)(=O)c1ccccc1-c1ccc(N2CCCC(NS(=O)(=O)c3ccccc3)C2=O)c(F)c1 +Cc1ccc(NC(=S)N2N=C(c3ccccc3O)CC2c2ccccc2O)cc1 +NC1=NC(c2cccc(F)c2)(c2cccc(NC(=O)c3ncc(Cl)cc3Cl)c2)CS1 +CC(C)CN(CC(O)C(Cc1ccccc1)NC(=O)OC1COC2OCCC12)S(=O)(=O)c1cccc(N)c1 +CCCN(CC1CC1)c1cc(C(=O)Nc2ccc(CN(C)CC(=O)O)cc2C)ncn1 +O=C(CCc1ccc(Cn2cccn2)cc1OCCc1ccc2ccccc2c1)NS(=O)(=O)c1ccc(F)c(Cl)c1 +O=C(CN1C(=O)C(NC(=O)c2cc3cc(Cl)sc3[nH]2)Cc2ccccc21)NCCO +O=C(C=Cc1ccc2c(c1)CN(C(=O)C1CC1)C2)NO +O=C(NCc1ccc(F)cc1)c1c(O)c2ncc(Cc3ccc(F)cc3)cc2n(CCN2CCCC2=O)c1=O +CC(C)C1NC(=O)C(Cc2cccc(Cl)c2)NCCOc2ccccc2CCCNC(=O)C(CNC(N)=NC#N)NC1=O +NC(=O)c1ccccc1NC(=O)Nc1ccc(Cl)c(Cl)c1 +Cc1cc(N2CCN(C)CC2)nc2ccc(NC(=S)N3CCN(c4ccc(Cl)cc4)CC3)cc12 +CN(C)S(=O)(=O)NC(=O)c1cc(Cl)c(OCC2CCC3(CCC3)CC2)cc1F +CN(Cc1cnc2nc(N)nc(N)c2n1)c1ccc(C(=O)NC(CCC(=O)Nc2ccc3c(c2)OCO3)C(=O)O)cc1 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccc(Oc2ccnc(NC(=O)C3CC3)c2)c(F)c1 +CC(=O)NC(CC(C)N1CCC(n2c(C)nnc2C(C)C)CC1)c1ccccc1 +Cc1c(C(=O)Nc2ccc(O)cc2)nn(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +CNC(=O)c1cccc(-c2[nH]nc3cc(C)nc(OC4CCOCC4)c23)c1 +CCOC(=O)C1=C(Nc2ccc3c(c2)c2ccccc2n3CC)SCC1=O +CCCCOc1ccc(C(=O)Oc2ccccc2-c2nc3cc(C)ccn3c2NC(C)(C)CC(C)(C)C)cc1 +N#Cc1ccc2nc(NCCC(F)(F)F)c(N3CCC(Oc4ccc(F)cc4F)CC3)nc2c1 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+O=C(O)c1ccc(CN2C3CCC2CC(Nc2ccc(Cc4ccncc4)cc2)C3)cc1 +Cc1cccc(-n2nc(C(C)(C)C)cc2C(=NO)C(=O)Nc2ccc(OCCN3CCOCC3)c3ccccc23)c1 +CCCCC1(CCCC)CS(=O)(=O)c2ccc(N(C)C)cc2C(c2ccc(OCCOCCOCCN(CCO)CCO)cc2)C1O +CCCCCCN1CC2C(C1)C2(C)c1cccc(NS(=O)(=O)c2cccnc2)c1 +Fc1ccc(-c2cc(-c3cccc(Cl)c3)[nH]c2-c2ccncc2)cc1 +CC(F)(F)c1cc(NC(=O)Nc2cc(F)cc(Oc3cc(NC(=O)C4CC4)ncn3)c2)ccc1Cl +Cc1cc(C)c(NC(=O)c2ccc3nc(NC(=O)C4CC4)sc3c2)c(C)c1 +CC(C)c1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2ccc3cc(C(=O)O)ccc3c2)cc1 +CC(C)C(NC(=O)C(S)C(C)c1ccccc1)C(=O)N1CCCCC1C(=O)O +COCCN(C)C(=O)c1ccc(NC(=O)N2Cc3ccc(F)cc3C2)cc1 +Fc1ccc(-n2cc(CCCCN3CCC4(CC3)OCc3cccc(F)c34)c3ccccc32)cc1 +COc1ccc(-n2c(C3CC(F)(F)C3)nc3c(NC(C4CC4)C4CC4)nc(C)nc32)cc1 +COc1cc2ncccc2cc1NC(=O)c1csc2cnc(N(C)C(C)C)nc12 +O=C1C(=NO)c2cc(Cl)ccc2N1Cc1cc(F)cc2c1OCOC2 +Cc1nc2cccc(-c3cc4c([nH]3)CCNC4=O)c2nc1NC(C)(C)CN1CCOCC1 +Cc1ccc(CC(CNC(=O)Cc2ccc(NS(C)(=O)=O)cc2)COC(=O)C(C)(C)C)cc1C +CN(C)C(=O)C(c1ccc(-c2ccc(F)cc2)cc1)C(N)C(=O)N1CCCC1 +O=C(Nc1cc(Nc2ccc3c(c2)OCc2ccc(C(=O)N4CCOCC4)cc2C3=O)ccc1F)c1cccs1 +Cc1noc(NS(=O)(=O)c2ccsc2C(=O)Cc2ccc3c(c2)OCO3)c1Cl +C[n+]1c2ccccc2nc2ccc(NC3CCCCC3N)cc21 +CN(CCC(=O)O)C(=O)C1CCCN(C(=O)CCC2CCNCC2)C1 +O=c1cc(-c2ccccc2)oc2cc(OCCCCCCN3CCC(O)CC3)ccc12 +CC(C)n1cc(C(=O)c2cncc(NC(=O)Cn3ccc(C4CC4)n3)c2)c2cnc(N)nc21 +O=C(O)c1n[nH]c2cc(F)c(-c3ccc(C4CCOCC4)cc3)cc12 +CCN(CC#N)C(=O)c1ccc(-c2nc(COc3cc(OC)cc4oc(-c5cn6nc(OC)sc6n5)cc34)cs2)cc1 +CCCCCCCCCCC=C(NC(=O)C1CC1(C)C)C(=O)O +CN1CCN(C2=Nc3cc(Cl)ccc3N(NC(=O)c3ccccc3N3CCN(C)CC3)c3ccccc32)CC1 +CNC(C)C(=O)NC(C(=O)NC1CCCN(CCc2ccccc2OC)C1)C(C)(C)C +CS(=O)(=O)c1ncc(C(=O)Nc2ccc(CCN3CCOCC3)cc2C2=CCCCC2)[nH]1 +COC(=O)c1ccc2c(c1)c1c(n2CCCN2CC(C)OC(C)C2)CCCC1 +N#CCC1(n2cc(-c3ncnc4[nH]ccc34)cn2)CN(C2CCN(C(=O)c3ccc4ncccc4c3)CC2)C1 +Cc1ccc(C2(O)C(=O)Nc3ccc(-c4c(C)noc4C)cc32)cc1 +OCCCNc1nccc(-c2c(-c3ccc(F)cc3)nn3cc(C(F)(F)F)ccc23)n1 +Cc1cn(C2CC(O)C(CO)(N=[N+]=[N-])S2)c(=O)[nH]c1=O +CCOC(=O)C(C)=CC(C(C)C)N(C)C(=O)C(NC(=O)C(NC)C(C)(C)c1cccc(C)c1)C(C)(C)C 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+FC(F)(F)Oc1cccc(-n2nnc3ccc(NCC4CC5(CCNCC5)C4)nc32)c1 +CN1CCC(Nc2nc(NN=Cc3ccc(Cl)cc3)nc3ccccc23)CC1 +O=C(NC(Cc1c[nH]c2ccc(O)cc12)c1cscn1)c1ccc2c(c1)nc(-c1ccco1)n2C1CCCCC1 +O=C(C=Cc1cn(C(C=Cc2ccccc2)Cc2ccc3ccccc3c2)nn1)NO +CCCc1nc2c(C)cc(NC(=O)c3ccc(C)cc3)cc2n1Cc1ccc(-c2ccccc2C(=O)O)cc1 +CCNC(=O)C1OC(n2cnc3c(Nc4ccc(OCC(=O)Nc5ccc(N6CCOCC6)cc5)cc4)ncnc32)C(O)C1O +CCCOc1cc(C2CCC(c3cc(OC)c(OC)c(OC)c3)O2)cc(N(O)C(=O)NCC)c1OCCC +O=C(NC1CC1)c1ccc(-c2nc3cccnc3n2C2CCCC2)cc1 +Cc1ccc(-c2nc(C)c(Cl)c(OCCCN3CCCCC3)n2)cc1 +CCN(Cc1ccccc1Cl)c1ccc(C(=O)NCc2cccnc2)cc1 +COc1cccc(N(C)C(=N)Nc2cc(SC)ccc2Cl)c1 +COc1cc(CC(=O)NCC(COC(=O)C(C)(C)C)Cc2ccccc2)ccc1O +CCOC(=O)C(Cc1ccc(C(=O)NCc2ccccc2C(F)(F)F)cc1)c1ccccc1 +O=C(O)Cc1nn(Cc2nc3c(ccc4ccccc43)s2)c(=O)c2ccc(Cl)cc12 +CN1C(=O)C(NC(=O)C(Cc2ccc(Cl)c(Cl)c2)c2ccncc2)N=C(c2ccccc2)c2ccccc21 +CC1NC(C(=O)N(CC#N)C2CC2)CC1C(=O)N(C)C +CC(C)=CCc1cc(C(=O)Nc2cc3ccc(OC4CCN(C)CC4)c(C)c3oc2=O)ccc1O +Cc1ncc(CO)c(CNc2ccc(OCCCCCCC(=O)NO)cc2F)c1O +O=C(Nc1ccc(OC(F)(F)F)c(F)c1)c1cccc(-c2cncnc2)c1 +CN1CCC(NC(=O)N2CCN(C3c4ccc(Cl)cc4CCc4cccnc43)CC2)CC1 +O=C(Cc1ccccc1)Nc1cc2cc[nH]c(=O)c2cc1Cl +O=C(NCc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1cnc2[nH]ncc2c1 +COc1ccc2c(nc(Nc3c(C)cccc3Cl)c3cnc(C=O)n32)c1OC +CC(C#N)C1CCC(c2nnn3cnc4[nH]ccc4c23)CC1 +C=CCNC(=O)c1ccc2c(c1)N=C(c1ccc(F)cc1)N(CCCC)C2 +Nc1ccccc1NC(=O)c1ccc(N2CCN3CCCCC3C2)nc1 +O=C(NC1CC1)c1cc2cccc(N3CCN(CCc4ccccn4)CC3)c2o1 +COc1ccccc1CC(=O)Nc1ccc(CCNCC(O)COc2ccc(O)cc2)cc1 +CCCOCC12Cc3cnn(-c4ccc(F)cc4)c3C=C1CCN(S(=O)(=O)c1ccc(C(F)(F)F)cc1)C2 +CN(C)c1ccc(-c2nc3c(c(Nc4ccc(CC(=O)O)cc4)n2)SCCC3)cn1 +OC1(c2ccc(Cl)c(Cl)c2)CC2CCC(C1)N2Cc1csc2ccccc12 +CC1CN(Cc2c[nH]nc2-c2nc(C#N)c[nH]2)CCN1c1ccc(C(F)(F)F)cn1 +CC(CCc1ncc[nH]1)C1CCC2(C)C3=C(CCC12C)C1(C)CCC(O)C(C)(C)C1CC3 +Cc1ccc(C(C)(C)C)c(SC2=C(O)OC(CCc3ccccc3)(C(C)C)CC2=O)c1 +O=C(NCc1nccs1)c1ccc2[nH]c(-c3ccc(C(=O)c4ccccc4C(F)(F)F)cc3)nc2c1 +Cc1c(Cc2ccccc2)c(=O)oc2cc(OC(=O)N(C)C)c([N+](=O)[O-])cc12 +Cc1nn(-c2ccc(Cl)cc2)c2c1c(=O)oc1ccccc12 +CC(C)C(NC(=O)Cn1c(-c2ccccc2)ccc(NC(=O)NCc2ccccc2)c1=O)C(=O)C(F)(F)F +Cc1noc(C)c1Cn1cc(NC(=O)c2cccc3c2OCO3)cn1 +Cc1cc(N)nc(C)c1CNC(=O)c1cnn(Cc2ccc(CN3CCCC3)cc2)c1 +CCCOc1c(OC)ccc2cc(C(=O)NC3CCCCC3)c(=O)oc12 +COCC(Nc1ncnc2c(C(N)=O)cccc12)c1ccccc1 +O=S(=O)(Nc1ccc(Cl)cc1)c1ccc2c(c1)CNC(CF)C2 +CN1Cc2c(-c3ccc(CC(=O)O)cc3)[nH]c3nccc(c23)-c2cc(F)ccc21 +Cc1cccc(-c2cc(Nc3ccncc3)c3ccccc3n2)n1 +Nc1cnc(-c2cc(Nc3cnc4ccccc4c3)nc(N3CCOCC3)n2)cn1 +Cc1nc(SCC(=O)C2(OC(=O)c3ccco3)CCC3C4CCC5=CC(=O)CCC5(C)C4C(O)CC32C)sc1C +Cc1cccc(Cl)c1C(=O)NC(Cc1ccc(-c2c(C(F)(F)F)n(C)c(=O)n(C)c2=O)cc1)C(=O)O +CC1COCCN1Cc1ccc(Nc2nccc(-c3cc(C#N)c(N4CCC(F)C4)c(C#N)n3)n2)cn1 +CN1CCN(Cc2ccc3c(c2)Cc2c(-c4ccc(-c5ccc(O)cc5)cc4)n[nH]c2-3)CC1 +Cc1cc(CCC(=O)c2sc(C)c3c2CC2C3C2(C)C)cc(C)c1OCCCNCCO +CCc1cc2c(cc1-c1cnoc1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +C=C=CC1(O)CCC2C3CCC4=CC(=NO)CCC4C3CCC21C +Cc1ccccc1-c1nc(C)c2c(C)nc3c(OCC(F)(F)F)cc(F)cc3n12 +CCN(CC)C1CCN(c2ccc(Nc3ncc4c5ccncc5n(C5CCCC5)c4n3)nn2)CC1 +CCSc1nnc2c(n1)OC(c1ccc(OC)cc1OC)N(C(C)=O)c1ccccc1-2 +CCn1nc(-c2cccc(C#N)c2)cc1C(=O)Nc1ccc(C2CNCCO2)cc1 +CCn1cc2c(n1)N=C(NC(=O)Nc1ccc(C)cc1)N1NC(c3ccco3)=NC21 +O=C(O)C1CCCCC1C(=O)Nc1cc(Cl)cc(Cl)c1 +CC(C(=O)NCc1ccc(C(F)(F)F)nc1N(C)S(=O)(=O)c1ccccc1)c1ccc(NS(C)(=O)=O)c(F)c1 +Cc1ccc2c(c1)nc(N1CCNCC1)n2Cc1ccccc1 +COc1cc2nc(N3CCN(C(=O)c4ccccc4)CC3)nc(N)c2cc1OC +CS(=O)(=O)CCNC1CCC(Nc2cc(-c3ccc(F)c(NCC4CCOCC4)n3)c(Cl)cn2)CC1 +CCc1nc(N)ccc1C#Cc1c(-c2ccc(C(=O)N3CCCC3)c(F)c2)ccnc1C +Cn1nc(C(N)=O)c2c1-c1nc(NCc3cccnc3)ncc1CC2 +COc1cc(O)c(CC=C(C)C)c2oc(-c3ccc(O)cc3)c(O)c(=O)c12 +COc1cccc2c(=O)n3c(nc12)-c1[nH]c2ccccc2c1CC3 +O=C1NC(=O)C(=Cc2cnn3c(NC4CC4)cc(N4CCN(C(=O)C5CC5(F)F)CC4)nc23)N1 +COc1ccc(NC(=O)C(=O)c2c[nH]c3cc(C#N)ccc23)cc1 +COc1cc(C2=NN(C(=O)c3ccc(F)cc3)C(c3ccc4c(c3)OCO4)C2)cc(OC)c1OC +COc1ccc(-n2nc(C#N)c3ncn(-c4ccc(-c5ccccc5CN5CCCC5)cc4)c(=O)c32)cc1 +O=C(c1cccc(F)c1-n1nccn1)N1CCC2CN(c3nc4cc(Cl)ccc4o3)C2C1 +CCc1ccccc1-c1cc(OC)c2c(n1)CCCC2N(CC)c1cccc2ccccc12 +CC1CN(c2cc(-c3n[nH]c4ccc(-c5ccc(C#N)cc5)cc34)ncn2)CC(C)O1 +Cc1oncc1CN(C(=O)CCC(C1CCCCC1)N1Cc2cc(Oc3ccccc3)ccc2N=C1N)C1CCCCC1 +O=C(O)c1ccc(-c2ccc3c(c2)CC(NCC(O)c2ccc(C(F)(F)F)cc2)CC3)cc1 +O=C(O)CC(c1ccc(Cl)c(Cl)c1)N(Cc1ccc(OCCN2C(=O)CCC2=O)c(F)c1)CC1CCCC1 +N=C(N)NC(=O)c1ccc(C2CCN(C(=O)c3ccccc3Cl)CC2)c(C(F)(F)F)c1 +CC(C)(C)NC(=O)C1CCC2C3CNC4=CC(=O)C5CC5C4(C)C3CCC12C +COC(=O)C1=C(C)N=C(C)C(=C(O)OC)C1c1ccccc1OCc1nonc1C#N +O=C(NCc1cccnc1)c1ccc(Br)c(S(=O)(=O)N2CCCCC2)c1 +O=C(NCCNc1ccnc2cc(Cl)ccc12)Nc1ccc(F)cc1 +CCC(CN1CCOCC1)N1C(=O)C(CC(=O)O)CC(c2cccc(Cl)c2)C1c1ccc(Cl)cc1 +COc1cccc(Oc2c(NCCOc3ncccn3)ncnc2NS(=O)(=O)c2ccc(C(C)(C)C)cc2)c1 +CC(=O)Nc1ccc2ccn(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1 +O=C1c2cnn(C3CCCCCC3)c2CCCN1C1C2CC3CC1CC(O)(C3)C2 +O=C(Nc1cc[nH]c(=O)c1)c1ccc(C(F)(F)F)cc1Oc1ccc(F)cc1F +O=C(O)CCC(=O)Nc1cc(Cl)c(-c2cccc3c(Br)c(O)ccc23)c(Cl)c1 +O=S(=O)(c1ccccc1)c1cn(C2CCN(Cc3ccccc3)C2)c2ccccc12 +Cc1n[nH]c(=O)cc1-c1ccc(OCCCN2CCCCC2)cc1 +O=C1NCCCN1CC1CNCCOC1c1ccc(Cl)c(F)c1 +O=C(O)CCCN1CC(c2nnn[nH]2)Oc2c(NC(=O)c3ccc(OCCCCc4ccccc4)cc3)cccc21 +O=C1NCCc2[nH]c(-c3ccnc(-c4cnc5ccccc5c4)c3)cc21 +CN1CCC(NC(=O)Nc2cccc3[nH]ncc23)c2ccccc21 +CNc1ccc2ccc3ncc(-c4cnn(C)c4)cc3c(=O)c2c1 +CCCc1ccc(Nc2ncnn3cc(C(=O)OC)c(C)c23)cc1O +COc1ccccc1N1CCN(C(=O)c2cc(-c3ccc(C#N)cc3)n[nH]2)CC1 +CCCCCCOc1cc2c(cc1OC)-c1c(OC)c(OC)cc3c1C(C2)N(C)CC3 +C=CCC1Oc2ccc(CO)c(OC)c2-c2ccc3c(c21)C(C)=CC(C)(C)N3 +OC(COc1cccc2ncccc12)CN1CCN(C2c3ccccc3C3C(c4ccccc42)C3(Cl)Cl)CC1 +O=C(OC1CC(n2cc(F)c(=O)[nH]c2=O)OC1CO)c1cccnc1 +COc1cc(-c2nnc3n2CCCC3(CO)Cc2ccc(F)c(F)c2)ccc1-c1cnc(C)o1 +COc1c(NC(=O)C(=O)c2ccc(OCCN3CCOCC3)c3ccccc23)cc(C(C)(C)C)cc1C(=O)NC1CC1 +N#CCNC(=O)C1(NC(c2ccc(-c3ccc(N4CCNCC4)cc3)cc2)C(F)(F)F)CCCCC1 +COc1cc(-c2c(C#Cc3ccc4ccccc4n3)nc3c(N4CCOCC4)ccnn23)ccc1C(=O)O +O=c1[nH]c(=O)n(C2CC(O)C(COP(=O)(O)O)O2)cc1Br +O=C(Nc1ccc(N2CCCCC2)cc1)C1=C(O)C(CCc2ccccc2)NC1=O +Cn1cc(C2=C(c3nnc4ccccn34)C(=O)NC2=O)c2ccc(Br)cc21 +Cn1cc(-c2cnc3ccc(NC(=O)NCCCC(C)(C)c4ccccc4)nc3n2)cn1 +CCN1CCN(c2cc(C)c3cc(NC(=O)C=Cc4ccc(OC(C)C)cc4)ccc3n2)CC1 +COc1cc2ncc3c(c(-c4ccc(C#N)cc4)nn3C)c2cc1OC(C(=O)NO)c1ccc(F)cc1 +CN(C)c1ccc(C=Cc2cnc(OCCO)c(Br)c2)cc1 +CC(=O)Nc1nc(C)c(C(=O)Nc2c(C)cc(C)cc2C)s1 +CCc1cc2c(cc1N1CCC(N3CCC(O)CC3)CC1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O +O=c1[nH]nc(CCc2ccc(C(F)(F)F)c(F)c2)cc1O +CC1CCC(C)N1Cc1cccc2c1-c1nc(N)nc(-c3ccccc3)c1C2=O +Cc1noc2cc(Oc3ccncc3C(=O)N3CCN(C4CC4)c4ccccc43)ccc12 +O=C(O)c1cccc2[nH]c(-c3c(F)c(F)c(-c4ccc(OCc5ccccc5)cc4)c(F)c3F)nc12 +COC1=CC(=O)CC(C)C12Oc1c(Cl)c(OC)cc(OCc3ccccc3)c1C2=O +NS(=O)(=O)c1nnc(NS(=O)(=O)c2ccc(NC(=O)c3c(F)c(F)c(F)c(F)c3F)cc2)s1 +COc1cc(OCc2cccc(-c3ncc(Cl)cc3Cl)c2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 +Cc1nc2c(N3CCOCC3)nccn2c1-c1ccc(N2CCCC2)nc1 +CCCC=CCCCc1cc(O)c2c(c1)OC(C)(C)C1CC=C(C)CC21 +O=C1C=CC2(C=C1)CCC1(CC(O)CC3(CCC4(C=CC(=O)C=C4)O3)O1)O2 +Cc1nn(C)c2nnc(Nc3ccc(S(=O)(=O)N4CCN(C)CC4)cc3)nc12 +O=C(NCC#Cc1ccc2ncccc2c1)c1cncn(Cc2ccc(F)c(F)c2)c1=O +CN(C(=O)Cc1ccc(Cl)c(Cl)c1)C(CN1CCCC1)c1cccc(OCC(=O)O)c1 +Nc1ncnc(Oc2ccc(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)c1C=NOC1CCCCC1 +COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1 +COc1cc(Nc2ncc3c(C)nc(-c4ccc(F)cc4)n3n2)cc(OC)c1OC +CCC(C)C=Cc1cc(C(=O)OC)cc2ccc(C(=N)N)cc12 +FC1(COc2cccc3ccc(-c4nnc5ccc(-c6ccccc6)cn45)nc23)CCNCC1 +CC(C)CC(NC(=O)C(Cc1ccccc1)N1CN(C(=O)CNC(=O)C(N)Cc2ccc(O)cc2)CC1=O)C(N)=O +O=C(NCc1ccc(Br)cc1)Nc1ccc2[nH]ncc2c1 +O=S(=O)(c1ccccc1)c1cn(C2CCCNC2)c2ncccc12 +Nc1ncnc2c1ncn2C1OC(CSCCCNC(=O)Nc2ccccc2)C(O)C1O +O=C1c2ccccc2S(=O)(=O)N1COc1nc2ccccn2c(=O)c1Cl +Cc1c(C(=O)NC2(C#N)CCOCC2)nn(-c2ccccc2F)c1-c1ccccc1 +COc1ccccc1N1CCN(CCCN2C(=O)CC(c3ccc([N+](=O)[O-])cc3)CC2=O)CC1 +Cn1cc(NC(=O)c2cnn3cccnc23)c(-c2cccc(Cl)c2)n1 +CC(C)Oc1cc(NC(=N)c2ccccn2)ccc1-c1ccc(NC(=N)c2ccccn2)cc1OC(C)C +CC(=O)Nc1ccc(C=CC(=O)NCC(=O)N(C)c2ccc(Cl)c(COc3cccn4c(Br)c(C)nc34)c2Cl)cc1 +Cc1onc(-c2ccc(Cl)cc2)c1C(=O)N(C)c1ccc(Cl)cc1 +COCC(NC(=O)c1cc(C)on1)C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)C1(C)CO1 +CC(=O)NCC(C)(C)c1ccc(C#Cc2cnc(NC3CCC3)nc2)cc1 +O=C(O)COCC1CCC(COC(=O)N(c2ccccc2)c2ccccn2)CC1 +COCCN1CCc2[nH]c(-c3ccnc(NC4CCOCC4)n3)cc2C1=O +Cc1cc(C(=O)Nc2ccc(N3CCOCC3=O)cc2)n(-c2ccc3cc(Cl)ccc3c2)n1 +CSc1nn(-c2c(Cl)cc(C(F)(F)F)cc2Cl)c(N)c1-c1cccs1 +CC(=O)N1CCN(C(=O)C=Cc2ccc(Sc3ccc4c(c3)OCC(CO)O4)c(Cl)c2)CC1 +CCC(C)COc1ccc(C(CC(=O)O)c2ccccc2)cc1 +Fc1ccc2occ(CCN3CC=C(c4c[nH]c5ccccc45)CC3)c2c1 +NCCNc1ccc([N+](=O)[O-])c2[nH]c3ccccc3c(=O)c12 +COCC(C)n1c(-c2cn3c(C)nnc3c(NC(C)C)n2)nc2cnc(N3CCOCC3C)cc21 +O=S(=O)(c1ccccc1)n1ccc2c(N3CCN(CCCNc4c5c(nc6ccccc46)CCCC5)CC3)cccc21 +CCN(CC)CCOc1ccc(Nc2cc(N(C)C(=O)Nc3c(Cl)cccc3C(F)(F)F)ncn2)cc1 +N#CCCn1c(C(=O)N2CCC(C(N)=O)(N3CCCCC3)CC2)cc(-c2ccc(Cl)cc2Cl)c1-c1ccc(Cl)cc1 +COc1cc(F)ccc1-c1ccnc2[nH]c(C3CNCCO3)cc12 +COc1cc(-c2cn(C3CCc4ccccc4N(CC(F)(F)F)C3=O)nn2)ccc1-c1ccncc1 +COc1cccc2[nH]c3c(N4CCC(C)CC4)ncnc3c12 +O=c1cc(-c2cccc(C=Cc3ccc4ccccc4n3)c2)oc2ccc(-c3nn[nH]n3)cc12 +COC(CC(CCN(C)Cc1ccc(-c2ccc(F)c(C)c2)cc1)C(=O)NO)c1ccc(F)cc1 +CN(c1ncccc1-c1ccc2c3[nH]ncc3c(=O)n(CC(F)(F)F)c2c1)C1CCCCC1 +C#Cc1ccc2nc(-c3ccc(NC(=O)Nc4cc(C(C)(C)C)on4)cc3)cn2c1 +Fc1ccc(-c2nn(CCCc3ccccc3)c3c2CNCC3)cc1 +COc1ccccc1C(=O)Nc1ccc(C(=O)N2Cc3cccn3Cc3ccccc32)cc1 +O=C(NCc1ccc(OC(F)(F)F)cc1)C1c2ccccc2C(=O)N1CCN1CCOCC1 +COc1ccc2ncc(=O)n(CCN3CCC(NCc4cc5c(cn4)OCCO5)C(OC)C3)c2c1 +OC(c1ccc(Cl)cc1)(c1ccc(Cl)cc1)c1cccc(F)c1 +Nc1nccc2c1CCC(C(=O)NC(Cc1ccccc1)c1nc(-c3ccc4c(N)n[nH]c4c3)c(Cl)[nH]1)C2 +COc1ccc(COc2nc(N3CCC4(CC4)C3)ncc2C(=O)NCc2ccc(F)cc2)cc1Cl +O=C(Nc1ccc(C(=O)N2CCN(c3ccc(Cl)cn3)CC2)cc1)N1Cc2ccccc2C1 +CCOC(CC(=O)O)c1ccc(OCc2cccc(OCOC)c2)cc1 +Nc1nc(N)c2cc(S(=O)(=O)c3ccc4ccccc4c3)ccc2n1 +Cc1nc(N)nc(-c2cc(CN3CCN(S(C)(=O)=O)CC3)cnc2Nc2cn[nH]c2)n1 +COc1cccc(C#CCOC(=O)c2c(O)nc3cc(Cl)ccc3c2O)c1 +CCCN(CCC1CCC(NC(=O)C=Cc2cccc(Cl)c2)CC1)C1CCc2nc(N)sc2C1 +CCCS(=O)(=O)Nc1cccc(Nc2ncnc3cc(OC)c(OC)cc23)c1 +C=CS(=O)(=O)N(C)C1CCN2CCc3ccccc3C2C1 +COc1ccc(CN2CCOC(COc3ccccc3)C2)cc1Cl +NC(=O)c1cnc(NC2CCCNC2)c2cc(-c3ccccc3)sc12 +Cc1cc(-c2n[nH]c3cc(NC(=O)NC(C)c4cc(Cl)ccn4)ncc23)ccn1 +CN1CCC(N(C)C(=O)c2cccc(Nc3nc4nc5c(cnn35)CCCCC(=O)Nc3cccc(c3)N4)c2)C1 +COc1ccc(CN2CCc3nc(N4CCCCC4)sc3C2)cc1 +Cc1ccc(-c2c(CN)c(CC(C)(C)C)nc(CC(C)C)c2C(=O)O)cc1 \ No newline at end of file diff --git a/Experiments/BBBP/running utils/moses250.txt b/Experiments/BBBP/running utils/moses250.txt new file mode 100644 index 0000000000000000000000000000000000000000..269a2e196f6f22a7b4317866c6ddea9bf1baea37 --- /dev/null +++ b/Experiments/BBBP/running utils/moses250.txt @@ -0,0 +1,250000 @@ +Cc1ccc(C(=O)OCC(=O)Nc2ccccc2SCC#N)o1 +O=C(NCc1ncccc1F)NC(CO)c1ccccc1 +CC1CCCCC1NC(=O)CN(Cc1cccnc1)CC1CCCO1 +CCC(C)(C)C(=O)Nc1cnn(CC(=O)OC)c1 +CCOC(=O)c1cc(NS(C)(=O)=O)cc(NS(C)(=O)=O)c1 +Cc1csc(C(Cc2cccs2)NC(=O)C2CCOC2)n1 +Cc1cc2oc(=O)cc(Cn3cnc4ccccc4c3=O)c2cc1C +Cn1cnc(CNC(=O)NCc2ccc(Oc3ccccc3)cc2)n1 +CC(C)C(C)NC(=O)NC1CCOc2c(Cl)cccc21 +O=C(NCC(O)Cc1ccccc1)c1cc(C2CC2)on1 +Cc1ccc(CNC(=O)NCc2cc(=O)[nH]c3ccccc23)cc1 +CC(C)CCOC(=O)CC1C(=O)NCCN1C(=O)C1CCCC1 +COc1cccc(C(=O)N2CCc3ccccc3C2)c1OC +COc1c(Cl)cccc1NC(=O)c1csc(C)n1 +CC1CC(C)CN(C(=O)CSc2nc(-c3cccs3)n[nH]2)C1 +COC(=O)C1=C(C)C(C(=O)CNc2ccccc2F)=NC1C +O=C(NCc1cccnc1)C1(c2cc(-c3ccco3)on2)CC1 +Cc1ccc(=O)n(C(C)C(=O)Nc2cc(F)cc(F)c2)n1 +O=C(CNC(=O)C1CCCC1)NCc1nnc2n1CCCCC2 +Cc1ccc(C(=O)Nc2ccc(C(N)=O)c(N3CCCCC3)c2)cn1 +CCOC(=O)N1CCN(S(=O)(=O)c2cc(C)ccc2C)CC1 +Cc1nc2cc(NC(=O)c3ccc4c(c3)OCO4)ccc2o1 +CCN(CC(C)C#N)C(=O)Nc1ccc(F)cc1Br +NS(=O)(=O)c1cccc(C(=O)NCC2CCCc3ccccc32)c1 +O=C(NCc1ccco1)C1CC12CCN(C(=O)CC1CCCC1)C2 +CCOC(=O)c1ccc(C(=O)NCc2ccncc2)cc1 +CC(=O)c1ccc(OCC(=O)NC2CCc3c(F)cccc32)cc1 +Cc1cnn(CC(=O)NC(C)Cc2cccc(Cl)c2)c1 +O=C(C1CCCc2sccc21)N1CCOCC1C1CC1 +CCOCc1ccc(NC(=O)c2c[nH]c3cccc(F)c23)cc1 +COc1ccccc1CN1C(=O)C2(OCCCO2)c2cc(C)ccc21 +C#CCNC(=O)CSc1nnc(COc2cc(C)ccc2C)o1 +Cc1n[nH]c(C2CN(CC(=O)NC3CCOCC3)CCO2)n1 +CC(=O)c1c(C)cc(C)c(CN(C)Cc2cnc(C)s2)c1C +Cc1ccc(NC(=O)NC(CO)Cc2c[nH]c3ccccc23)c(F)c1 +Cc1nn(CCC(=O)NCc2cccc(F)c2)c2ccccc12 +COC(=O)C1CCN(C(=O)c2ccc(CN3CCCC3=O)cc2)CC1 +CCCSc1nnc2c(n1)OC(C)N(C(C)=O)c1ccccc1-2 +Cn1c(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)cccc1=O +COc1cc2c(c(Cl)c1O)C(C1CCOCC1)NCC2 +CCCCNC(=O)C(C)Sc1nnc2ccc(C(F)(F)F)cn12 +CNC(=O)C1CN(C)CCN1C(=O)c1cn(C)nc1C +CCC(CC)C(=O)NC1CC(=O)N(c2ccc(F)cc2)C1 +COc1ccc(Cl)cc1C(=O)N1CCOC(C)(C)C1 +CCOc1ccc(-n2nc(C#N)c(=O)n(CC)c2=O)cc1 +Cc1cnn(Cc2ccc(Cl)cc2)c1NC(=O)NCC1(C)COC1 +Cc1ccc(-c2cc(C(N)=O)c3ccccc3n2)cc1 +Cc1ccn(-c2ccc(N(C)CCCc3n[nH]c(N)c3C#N)nn2)n1 +O=C(NCc1cccc2cccnc12)NC1CCC2(CC1)OCCO2 +O=C(c1csc(-c2ncccn2)n1)N1CCCC1 +Cc1ccc(NC(=O)CC(F)(F)F)c(Br)c1 +Cc1nc(Nc2ncccn2)cc(C2CCCN2C(=O)CC(C)C)n1 +Cc1cccc(NCc2ccc(C#N)cc2)c1C(N)=O +CC(=O)N1CCc2ccccc2C1CC(=O)NCc1ccccn1 +CC(C)N(C(=O)CN1CCN(S(N)(=O)=O)CC1)C1CCCC1 +Cc1nc(C(=O)Nc2nc[nH]n2)c(-c2ccccc2)s1 +Cc1csc(NC(=O)c2nn(C(C)C)c(=O)c3ccccc23)n1 +CCCN1C(=O)C2CCC1CN(C(=O)Cc1ccc(OC)cc1)C2 +CCCc1noc(CS(=O)(=O)c2ccc(C)cc2)n1 +C#Cc1cccc(N(CC)C(=O)C(C)Sc2ccccn2)c1 +CC(C)C(CNC(=O)NC1(C)Cc2ccccc2C1)N1CCOCC1 +CC1CN(C(=O)Nc2ccc(Cl)c(Cl)c2)C(C)CC1=O +Cc1occc1COC(=O)C(C)NC(=O)C(C)(C)C +CC(=O)Nc1ccc(S(=O)(=O)NCc2cc(C)oc2C)c(C)c1 +Cn1cc(C(O)CNC(=O)c2cnccn2)c2ccccc21 +COC(=O)c1cccc(NC(=O)NCCC(=O)NC2CCCC2)c1 +CC(c1ccccc1Cl)N1CCN(C(=O)Nc2cnn(C)c2)CC1 +CCc1nc2n(n1)CCCC2NC(=O)N1CCC(C)CC1C +C=CCCC(=O)Nc1cc(OC)c(Br)c(OC)c1 +CCc1nn2c(nnc3c(=O)n(N(C)C)ccc32)c1-c1ccccc1 +NC(=O)C1CCCN(C(=O)Cn2cccc(C(F)(F)F)c2=O)C1 +O=C(NC1CCCC1)c1cccc(NS(=O)(=O)c2ccccc2)c1 +COC(=O)C(NC(=O)c1cnc(C)cn1)C(C)C +Cc1nc(C)c(-c2cc(C(=O)c3ccncc3)c(N)o2)s1 +O=C1CN(C(=O)c2cn(Cc3ccccc3Cl)nn2)CCN1 +CCOc1ccc(C(C)Nc2ccc3nnnn3n2)cc1 +CCCn1c(C)ccc(C(N)c2cc(C)ccc2C)c1=O +C=C(C)CN(CC)C(=O)C1CCCN(C(=O)C(C)C)C1 +O=C(c1ccsc1)N1CCCC1c1nc(-c2ccccc2)n[nH]1 +O=C(Nc1c(F)cccc1F)C1CCCN1C(=O)c1ccccc1 +NS(=O)(=O)N1CCCCC1c1nc(-c2ccccc2)no1 +CC(=O)Nc1ccc(C)cc1NCC(=O)N1CCC(C)CC1 +CN(C(=O)c1ccc(S(C)(=O)=O)cc1)C1CCc2ccccc21 +CC1=CC(C)=NC(=O)C1CNC(=O)c1cc(C2CC2)nc2ccccc12 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)N2CCCCC2)c1 +Cc1ccc(NC(=O)CCNC(=O)N(C)Cc2ccccc2)nc1 +Cc1n[nH]c2c1C(c1ccncc1)C1=C(COC1=O)N2 +CCCNC(=O)CSc1nnc(-c2ccc(C)cc2)n1C +Cc1ccccc1C(=O)Nc1cc(-c2ccccn2)no1 +CCOc1ccc(F)c(C(=O)Nc2nc(C)ns2)c1F +COCC(=O)N1CCC(C(=O)c2ccc3c(c2)OCCO3)CC1 +Cn1ccnc1C(O)(CC(=O)Nc1ccccc1F)C(F)(F)F +O=C(C1CC(=O)N(c2cc(Cl)cc(Cl)c2)C1)N1CCC(O)C1 +O=C(CNC(=O)c1ccc(-n2ccnn2)cc1)Nc1cccc(F)c1 +CN(CC(=O)N1CCC(O)(C(F)(F)F)CC1)C(=O)OC(C)(C)C +NC(=O)CCCNC(=O)c1sccc1C1CC1 +Cc1cc(F)ccc1NC(=O)c1cc(-c2cccnc2)[nH]n1 +CC(=O)N1CCN(CC(O)c2c(C)c(C)cc(C)c2C)CC1 +CCOc1cc(C)ccc1NC(=O)CNS(C)(=O)=O +C#CCC(NC(=O)C1OCCc2ccccc21)C(N)=O +Cc1ncc(C(=O)NCCN2CCN(c3ncccn3)CC2)s1 +NC(=O)COc1ccc(OCc2cc(F)cc3cccnc23)cc1 +CCOc1ccccc1Nc1ncc(N)cc1OC +CNS(=O)(=O)c1ccc(S(=O)(=O)NC(C)CO)cc1 +Nc1cccc(CNC(=O)c2ccccc2Br)c1 +Cn1c(=O)n(CC(=O)NCCS(N)(=O)=O)c2ccccc21 +CCOC(=O)CC(C)CNC(=O)c1cccc(C)c1O +O=C(CSc1cn[nH]n1)Nc1cccc(C(F)(F)F)c1 +COc1cc(Cl)c(-c2cc(C(=O)OC(C)C)[nH]n2)cc1OC +CCNS(=O)(=O)c1cccc(C(=O)NCc2cccnc2)c1 +O=C(NCc1cn2ccccc2n1)Nc1ccccc1F +COc1cc(OCc2ccccc2)cc(O)c1C(C)=O +CCC(C)n1ncc(C(=O)N(C)Cc2ccoc2C)c1C1CC1 +CN(C(=O)CSc1cccc(N)c1)C1CCCCC1 +Nc1ccc(C(=O)NC2CNCc3cc(Cl)ccc32)cc1 +COC(=O)CCC(=O)Nc1c(Cl)cccc1Cl +COC(=O)c1ccc(NCc2ccc(O)cc2)cc1 +CCOc1cccc2sc(N3CCN(C(=O)C4CCC4)CC3)nc12 +CN(C)C(=O)C1CCCN(c2nnc3ccc(C(F)(F)F)cn23)C1 +COc1cc(Cl)c(CC2C(=O)Nc3ccccc32)cc1OC +CC(C)(C)CCC(=O)Nc1cccnc1-n1cccn1 +CCCc1nnc(NC(=O)Cn2c(=O)oc3ccccc32)s1 +Cc1ccccc1CN(C)C(=O)c1ccnc(NC2CC2)c1 +Cc1ccc(NC(=O)c2ccc(S(C)=O)cc2)c(O)c1 +CC1CC(=O)c2c(N)ccc(Cl)c2S1(=O)=O +CC(NC(=O)c1ccccc1NC(=O)c1ccccc1)C(N)=O +CCCCCCSc1nc(OC)cc(=O)n1C +Cc1ccc(Cc2nnc(NC(=O)CCc3ccccc3)o2)cc1 +COCc1ccccc1NC(=O)CCc1ccccn1 +Cc1ccsc1C(O)CNC(=O)NC1CCCCC1 +CC(c1c(F)cccc1F)N1CCN(C(=O)c2ccccc2F)CC1 +COC(=O)c1sc(Cc2ccc(C)cc2)nc1C +COc1ccc(C)cc1C(C)NC(=O)N1CCC(CC(N)=O)CC1 +CNC(=O)c1ccccc1NCc1nc(-c2ccc(C)c(F)c2)no1 +CNS(=O)(=O)c1cc(C(=O)N2CC(C)OC(C)C2)ccc1OC +COc1cc(C)c(C(=O)N(C)c2cccc3ncccc23)cc1OC +O=C(CCc1ccc(F)cc1)N1CCN(CC2CCCC2)C(=O)C1 +O=C(NCC1(c2ccccc2)CCOCC1)c1n[nH]c(=O)[nH]1 +O=C(NCc1cc(-c2ccco2)on1)c1cc(-c2ccccc2)on1 +COCC(C)NC(=O)Nc1cccc(OCc2cccnc2)c1 +CCC1COC(C)CN1S(=O)(=O)c1cccc(N)c1 +O=C(c1ccncc1)N1Cc2cnn(Cc3ccc(F)cc3)c2C1 +CCOC1CCCN(CC(=O)c2c(N)n(CC)c(=O)[nH]c2=O)C1 +COC(=O)C1=C(N)Oc2[nH]nc(C)c2C12C(=O)N(C)c1ccccc12 +CC(C)CCCNC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +Cc1ccc(S(=O)(=O)Oc2ccc(Cl)cc2CO)cc1 +CCOc1cc(N)cnc1NCCc1ccc(OC)cc1 +Cc1ccc2c(c1)C(=O)CC(C(=O)N1CCOCC1)C2 +CCCNC(=O)CN(CCC)C(=O)c1cccc(C)c1O +COc1ccc(NC(=O)COC(=O)c2cccc(F)c2)c(OC)c1 +O=C(Cc1ccc[nH]1)Nc1nc(-c2ccccc2Cl)ns1 +CNC(=O)c1ccc(NC(=O)c2ccc3ccccc3n2)cc1 +COc1cc(Br)c(NC(=O)C2CCC2)cc1OC +CCc1ccc(C(=O)N2CCC3(CC(=O)c4ccccc4O3)C2)cc1 +c1cnc(N2CCC23CCN(c2nccs2)CC3)nc1 +Cc1csc(N2CCN(C(=O)Nc3c(C)cccc3C)CC2)n1 +N#Cc1cccc(S(=O)(=O)NCCc2cccc3cccnc23)c1 +Cc1c(C(=O)OCc2ccccn2)cnn1-c1ccncc1 +Cc1nn(-c2ccccn2)c(C)c1N1CCN(Cc2ccoc2)CC1 +Cc1ccc(C)c(N(C)C(=O)c2cnc(C3CCCO3)s2)c1 +CN(C)C(=O)CN(C)C(=O)CCCNC(=O)c1ccc(Cl)cc1 +O=C(NCCCOC1CCCC1)c1ccc(F)nc1 +O=C(Nc1ccc(F)cc1F)Nc1cccc2c1OCCO2 +CC(C)C(=O)N1CCC(C(=O)NC(C)C2CC2)CC1 +Cc1ccc(N)c2ccnc(C(=O)N3CCc4ccccc43)c12 +O=C(NCCSc1ccccc1)c1cccnc1-n1cncn1 +Cc1csc(=O)n1CCC(=O)NCC(C(C)C)N1CCOCC1 +COc1cc2nc(C)c(=O)n(CC(C)C#N)c2cc1OC +CC1=C(C(=O)N2CCCCC2)C(c2ccncc2)n2ncnc2N1 +N#Cc1ccc(CCC(=O)NCCc2ccc3c(c2)OCO3)cc1 +CCc1cccc(C)c1NS(=O)(=O)c1c(C)[nH]c(=O)[nH]c1=O +COCC(NC(=O)c1nc(C)n(-c2ccccc2Cl)n1)C(N)=O +CN(CC(=O)Nc1ccc(S(N)(=O)=O)cc1)c1ccc(F)cc1 +CC(CN1CCOCC1)NC(=O)CCc1ccccn1 +CC(Cc1cccc(F)c1)C(=O)NCc1ccncc1 +Cc1c(Cl)cccc1NCc1ccc(C(N)=O)cc1F +COC(=O)c1cc(-c2nccn2-c2ccc3cn[nH]c3c2)ccc1O +O=C(c1ccc(F)c(S(=O)(=O)N2CCCCC2)c1)C1CC1 +Cn1nc2c(c1NC(=O)C1CC1c1ccccc1C(F)(F)F)CCC2 +Cc1noc(C)c1CC(=O)N1CC(C)(C)C(C)(O)C1 +CCc1cccc(N2CCC(NC(=O)c3ccnc(C)n3)CC2)c1 +Cc1ccc(C(=O)OCC(=O)N2CC(C)OC(C)C2)c(O)c1 +COCCC(=O)Nc1c(N)n(C)c(=O)n(C)c1=O +CCN(Cc1cnc2ccccn12)C(=O)c1ccc(C)cc1 +Cc1ccccc1C(=O)NCC(=O)N1CCCCCC1 +Cc1nnc(COC(=O)c2cnc(C3CCCO3)s2)n1C +CCc1ccccc1NC(=O)c1ccc(NC(C)=O)cc1 +CCCCn1ncc(-c2ccccc2)c(CO)c1=O +O=C(NCc1ccc(OCc2cccnc2)cc1)NC1CCCC1 +CCc1nncn1CCNC(=O)c1cccc(-c2ccoc2)c1 +COc1ccc(CC(=O)NC(C)CCc2ccco2)cc1F +FC(F)Oc1ccc2c(c1)CCNC2Cc1cccnc1 +CCc1cnc(CN(C)C(=O)NC2CCN(c3ccccc3)C2)s1 +CCn1cnnc1CNC(=O)Cc1csc(-c2ccccn2)n1 +CCCCCNC(=O)C(O)(c1ccccc1)c1ccccc1 +Cc1cc(OCC(=O)C(C#N)c2ccccn2)ccc1C(C)C +Cc1cc(C)c(C(=O)Nc2ccc3c(c2)OCC(=O)N3)c(C)c1 +O=C(NCCC(=O)N1CCN(CCO)CC1)c1ccc(F)cc1F +O=C(NCC(O)c1ccc2c(c1)CCO2)c1cc(-c2ccco2)on1 +O=C(COC(=O)C12CC3CC(CC(C3)C1)C2)N1CCCC1 +COc1ccc(CC(=O)NCC#CCOc2ccccc2OC)cc1 +CCn1nnc2cc(C(=O)N3CCOc4ccc(F)cc43)ccc21 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1n[nH]c2ccccc12 +COc1ccc(C(=O)Nc2cccc(O)c2)c(N)c1 +COC(=O)c1cccc2c1CCCN2C(=O)c1ccc2ccccc2n1 +CC1CCCCN1S(=O)(=O)c1ccc(C(=O)NC2CC2)cc1 +COc1ccc(C(=O)NCCCNC(=O)c2ccncc2)cc1 +Cc1nc(C2CCN(C(=O)c3c[nH]c4cccc(F)c34)CC2)no1 +CCOC1COCC1NC(=O)CCc1nc(-c2ccccc2)no1 +CCN1CC(C(=O)NCCCc2nc(C)cs2)CC1=O +O=C(NCCOc1ccc2c(c1)CCC2)C1CCCO1 +CCCCC(=O)NCCn1nc2ccccn2c1=O +O=C(Nc1ccsc1)c1c[nH]nc1-c1cccc(Cl)c1 +O=C(c1cccn1-c1nnc(N2CCCCC2)s1)N1CCOCC1 +Cc1ccsc1C(=O)Nc1cccc(C#Cc2ccccn2)c1 +Cc1cc(C)c(C(=O)Nc2ccc(Oc3ccncc3)cc2)c(=O)[nH]1 +O=C(CCNC(=O)c1cc2ccccc2s1)NCc1cccnc1 +CC(C)CCNC(=O)C(C)N1CCN(C(=O)N2CCOCC2)CC1 +Cc1cc(NC(=O)C2CCN(C(=O)C3CC3)CC2)nc(C(C)C)n1 +CCn1c(N2CCC(C(=O)NCCOC)CC2)nc2ccccc21 +N#CCOc1cccc(CC(=O)NCc2ccc3c(c2)CCC3)c1 +CCc1nn2c(=O)cc(CSc3ccccc3N)nc2s1 +COCC(C)N1CCN(S(=O)(=O)c2cccc(Cl)c2)CC1 +COc1ccc(N2C(=O)NC3CC2(C)Oc2c(OC)cccc23)cc1 +Cc1noc(N)c1C(=O)OCC(=O)NCC1(c2ccccc2)CC1 +COc1ccc(C(O)C(=O)N2CCNCC2)cc1C(C)C +CN(CC(=O)c1ccc(O)cc1)C(=O)C(c1cccc(F)c1)N(C)C +CNC(=O)NCC(=O)N1CCCC1COc1ccccc1 +COc1ccc(C(C)N(C)C(=O)C(C)NC(N)=O)cc1 +O=C(NCCc1ccccc1)C1CC(=O)N(C2CCCCC2)C1 +COC1CCC2OCCN(Cc3nc(CC(C)C)no3)C2C1 +CCCOC1CCCN(C(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)C1 +O=C(Cc1csc(Nc2ccccc2)n1)NCc1ccco1 +CCn1nccc1C(=O)N1CCC(c2cc(N)on2)CC1 +O=C(Nc1cccc(N2CCCCC2=O)c1)NC1CCC(O)CC1 +COC(=O)C1=C(C)NC(=O)CC1C(=O)Nc1ccc2c(c1)OCO2 +Cc1ccc(-c2nnc3sc(-c4ccc(N)cc4)nn3c2=O)cc1 +COC(=O)c1cc(-c2ccccc2)sc1NC(=O)C1CCCO1 +Cc1nc(SCC(=O)N(C2CCCC2)C2CC2)oc1C +COC(=O)NCC(=O)NC1(C(=O)OC)CCCCCC1 +Cc1ccc(N2CCCN(C(=O)c3cccs3)CC2)nn1 +O=C(NCC1CC1)C1CCCN(C(=O)Nn2cnc3ccccc32)C1 +Cc1ncc(S(C)(=O)=O)c(NCCCN2CCc3ccccc32)n1 +O=C(NCCc1nccs1)Nc1ccc(Cl)cc1C(F)(F)F +O=C(Cn1c(=O)oc2ccccc21)NCc1ccc2c(c1)OCO2 +COc1ccccc1C(=O)c1c(N)oc2ccccc12 +CC1CCC(OCCCC(=O)Nc2ccccc2N)CC1 +COc1ccc(C(C)=O)cc1CC(=O)NC(C)Cc1ccccc1F +COc1ccc(F)cc1C(=O)CNc1cccc(F)c1 +C#CCNC(=O)CSc1nnc(-c2ccccc2)n1CC +N#CC1(NC(=O)CN2CCN(C(=O)c3ccccc3)CC2)CCCC1 +CNC(=O)c1cccc(OC(=O)Cc2c[nH]c3c(C)cccc23)c1 +CC(C)C(C)N(Cc1ccco1)C(=O)CCn1nnc2ccccc21 +O=C(Nc1ccccc1F)N1CCCC(CO)C1 +COc1ccc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)cc1 +CCC1CCCN(C(=O)c2ccc(C(F)(F)F)nc2)C1 +COc1ccc(CCC(=O)Nc2cc(C#N)cn2C(C)(C)C)cc1 +COCc1c(C(=O)OCC2CCC(=O)N2)sc2cccc(F)c12 +CC(C)NC(=O)C1(S(=O)(=O)c2ccc(Cl)cc2)CC1 +CC(=O)Nc1ccccc1CN1CCOC(c2cccc(F)c2)C1 +Cc1n[nH]c(C)c1S(=O)(=O)Nc1cnn(C2CCOCC2)c1 +CC(=O)Nc1ccc(C(=O)Nc2c(Cl)cc(O)cc2Cl)cc1 +CC(Sc1nnc(-c2ccc[nH]2)o1)C(=O)NCc1cccs1 +Cc1cc(C)nc(SCC(=O)Nc2cc(F)ccc2F)n1 +O=C(c1ccoc1)N1CCCN(c2nccs2)CC1 +Cc1c(NC(=O)Cc2cn3ccsc3n2)cccc1C(N)=O +CC1Cc2ccccc2N1C(=O)COC(=O)CCNC(=O)C(C)(C)C +COc1ccc(-c2cc(-c3ccccc3)[nH]c(=O)c2C#N)cc1OC +NS(=O)(=O)c1ccc2c(c1)CCN2Cc1ccc(F)cc1Cl +Cc1ccc(C)c(CS(=O)(=O)c2nnc(C)n2CC(N)=O)c1 +COCCNC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CC(C)(C)OC(=O)NC1(c2noc(C3(C)CC3)n2)CCC1 +Cc1cnccc1NC(=O)c1ccc(-c2cscn2)cc1 +Cc1ccc(C)c(CC(=O)Oc2ccc(N(C)S(C)(=O)=O)cc2)c1 +CC(=O)NC1(c2ccccc2)CCN(c2cc(C)nc(N)n2)CC1 +Cc1ccsc1CNc1cc(C(N)=O)cc(F)c1C +CC1CCCCN1S(=O)(=O)N1CCCN(c2ncccn2)CC1 +O=C(COC(=O)c1n[nH]c(=O)c2ccccc12)c1ccc(F)c(F)c1 +CCCNC(=O)CNc1ccc(C(=O)N2CCOCC2)c(Cl)c1 +COc1ccc(CCC(=O)N(Cc2ccncc2)C2CC2)cc1 +Cc1cc(C)n(C(C)CC(=O)Nc2ccc(Cl)cc2F)n1 +CCCNC(=O)C1COC2(CCCCC2)N1C(=O)C1CC1 +COCCS(=O)(=O)NC(C)c1ccc(C#N)cc1 +O=C(N1CCOCC1)N1CCN(c2nc3ccccc3s2)CC1 +COCCNC(=O)NCc1noc(-c2ccsc2)n1 +Cc1ccccc1CNC(=O)CN(C)Cc1nc2ccccc2s1 +c1cnc(-n2nc(-c3cccnc3)c3c2CCNC3)nc1 +CC(Sc1nnc(-c2cccnc2)n1C1CC1)C(N)=O +CN(C)S(=O)(=O)Nc1cccc(OC(=O)N2CCCCC2)c1 +COC(=O)c1cccc(-n2nc(C(F)(F)F)c3c2CCNC3)c1 +O=C(c1cn(-c2ccccc2)nn1)N1CCc2ccc(Cl)cc2C1 +COc1cncc(N2CCN(c3ccc(C(C)=O)cc3F)CC2)n1 +CC(C)Nc1c(Cl)cccc1NC(=O)c1cnc2c(c1)nnn2C +CCC(C)Oc1ccc(NC(=O)N(C)Cc2cc(C)on2)cc1 +Cc1ccc(C(=O)N2CC(=O)Nc3ccccc32)cc1F +Cc1ccc(OCC(=O)Nc2cccc(Cn3cccn3)c2)cc1 +Cn1c(CCC(N)=O)nnc1SCc1ccccc1 +O=C(NCCc1ccc(F)cc1)C1CS(=O)(=O)c2ccccc2O1 +COc1ccc(N(C)C(=O)c2ccc(-n3cccc3)nc2)cc1OC +COc1ccc(C(=O)Nc2cc(Cl)ccc2-n2cncn2)nn1 +O=C(CSc1nc(C2CC2)n[nH]1)Nc1ccc2c(c1)OCCO2 +CC(C)(CNC(=O)c1nc2ccccc2s1)c1ccncc1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)Nc1ccc2c(c1)CCC2 +Cc1ccn2c(=NC(=O)c3ncccc3OC(C)C)[nH]nc2c1 +CC(=O)c1ccc(NCCOc2ccccc2F)cc1 +CCn1c(-c2cc(NC(=O)c3cccnc3)[nH]n2)cc2ccccc21 +CNS(=O)(=O)CCCN(C)Cc1nc2ccccc2n1C +CCC(=O)Nc1cc(C(=O)NC2CCCC2)ccc1Cl +CC(=O)c1c(C)nc2nc(-c3ccc(C)cc3)nn2c1C +COc1cccc(-c2nnn(CC(=O)NC3CCOCC3)n2)c1 +CC1CN(S(=O)(=O)CCc2ccccc2)CC(C)O1 +Cc1nc2sccn2c(=O)c1NC(=O)c1ccccc1 +Cc1nc2cc(C(=O)N3CCCN(c4ccccc4C)CC3)ccc2[nH]1 +CC1CCC(N(C)C(=O)Cn2cnc3ccc(Cl)cc3c2=O)CC1 +CNC(=O)c1ccc(Cl)c(NCc2ccc(C#N)cc2)c1 +CCN1C(=O)C2(CC(=O)Nc3[nH]ncc32)c2cc(C)ccc21 +Cn1cc(NC(=O)c2cc(NC(=O)NC(C)(C)C)ccc2Cl)cn1 +Cc1ccc2cc(C(=O)N(C)C3(C#N)CCC3)c(C)nc2c1 +Cc1nc(CNC(=O)N2CCC(c3ccc(F)cc3)C2)oc1C +Cc1ccc(C(=O)NC2CCCCNC2=O)cc1C +CC(Cn1cncn1)Nc1nc(C2CCCC2)nc2c1cnn2C +CCn1c(-c2cccc(Cl)c2)nnc1S(=O)(=O)CC(=O)NC +Cc1cc(NC(=O)C(NC(=O)Nc2ccccc2)C(C)C)ccn1 +CCCc1n[nH]c(SCc2cc(=O)c3cc(C)cc(C)c3[nH]2)n1 +CCn1c(C)cc(C(=O)N2CCCCCC2c2ccncc2)c1C +O=C1CCCN1CCNc1cc(-c2ccccc2F)nc2ccnn12 +c1cc(-c2nc(C3CC3)no2)nc(-n2cccn2)c1 +Cc1cccc(NC(=O)CSc2noc(-c3ccncc3)n2)c1C +O=C(NCc1nc2ccccc2[nH]1)c1ccc(Br)cc1 +Cc1n[nH]cc1NC(=O)COc1ccccc1Cl +COc1ccc(-c2c3c(nc4ncnc(N)c24)CCCC3)cc1 +COc1cc(Nc2ccc(NC(=O)c3ccco3)cc2)nc(C)n1 +COc1ccc(N)cc1CNc1nc(C)cc(C)c1C#N +CN(C(=O)Cc1cccc(OCC#N)c1)C1CCC(C)(C)CC1 +O=C(Nc1ccc(Cl)cc1)C1CN(C(=O)c2cccs2)C1 +Nc1ccccc1Cc1nn(CCO)c(=O)[nH]c1=O +CC(=O)c1cccc(OC(=O)c2cc(C(N)=O)cs2)c1 +CCOc1ccc(C(=O)N2CCC(CO)C2)cc1OCC +CC(c1cccc(O)c1)N(C)C(=O)c1ccc(-n2cnnc2)cc1 +CCOCCC(=O)Nc1ccc(OC)cc1OC +CC1CN(CC2CCCN2Cc2n[nH]c(=O)[nH]2)CC(C)O1 +CC(C)Sc1ccc(COC(=O)C2CCCN2)cc1 +CCOC(=O)Nc1nc(CC(=O)Nc2ccc(C)cc2)cs1 +O=C(NC1CCCC1)c1n[nH]c2c1CCc1ncccc1-2 +CCc1nc(CS(=O)(=O)c2nccn2-c2ccc(C)cc2C)no1 +CCc1cccc(NC(=O)CCn2nc(-c3cccs3)oc2=O)c1 +CC(C)NS(=O)(=O)Cc1c(Cl)cccc1Cl +COCCOCC(=O)Nc1cnn(-c2ccccc2F)c1 +O=C(NC1CCCc2ccccc21)C1CCCCC1 +CCc1c(C)sc2nc(-c3ccc(S(C)(=O)=O)cc3)[nH]c(=O)c12 +Cc1ccc(OCc2cccc(C(=O)OCc3ccccn3)c2)cn1 +CCc1cccc2c(C(=O)CN3CCC(n4cncn4)CC3)c[nH]c12 +O=C(CCc1cccc(F)c1)NCC(=O)N1CCCc2ccccc21 +CCCOCc1nc(NCC)c2ccsc2n1 +Cc1nc2cc(NC(=O)c3cn(C)nn3)ccc2s1 +COc1cc(C(=O)Nc2cccnc2-n2cccn2)cc(OC)c1C +O=C(NCCO)NCC12CC3CC(CC(C3)C1)C2 +COc1ccnc(NC(=O)c2cc3cc(C)c(C)cc3o2)c1 +CC1CC1CNC(=O)Nc1ccc2c(c1)NC(=O)CO2 +CCn1cc(C#N)c(=O)n(CCCc2cnn(C)c2)c1=O +O=C(Cc1ccc(F)cc1)N1CCc2ccccc2C1 +Cc1cc(C)n(-c2ccc(NCc3cccc(C(N)=O)c3)cc2F)n1 +CN(CC(=O)OCCC(C)(C)C)S(C)(=O)=O +CCCCc1nc2c(N)cccc2n1CC(=O)NC +Cc1sc(NC(=O)c2ccc(C#N)cc2)c(C(N)=O)c1C +COC(=O)C1=C(C)C(C(=O)Nc2ccc(OC)cc2)=NC1C +C=CCNS(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +CC(=O)c1nc2ccccc2n1C(=O)C(Cl)(Cl)Cl +COC(=O)c1nn(-c2ccccc2C)c2c1CCC2 +COc1ccc(NC(=O)CN2CCCCCC2=O)cc1OC +COc1ccc(Cl)cc1C1(C#N)CCC(=O)CC1 +Cc1cccc(NC(=O)C(C)S(=O)(=O)c2nncn2C)c1C +Cc1nc(-c2cccs2)sc1C(=O)NCc1cn[nH]c1 +COc1cccc(C(=O)CCC(=O)N(C)c2ccccc2)c1 +COCC(NC(=O)c1cc2cc(C)ccc2nc1C)c1ccnn1C +O=C(Nc1nccs1)c1cccc(C#CCO)c1 +CNS(=O)(=O)c1cccc(CNC2CCc3ccccc3C2)c1 +COc1cc(C#N)ccc1OC(=O)C(C)(C)c1ccccc1 +NC(c1cnc2c(Cl)cc(C(F)(F)F)cn12)C(F)(F)F +CCNC(=O)CCCC(=O)NC1CC1c1cccc(Cl)c1 +CN(CCOCC1CC1)C(=O)Nc1ccc(Cl)cc1F +O=C(NC1CC1)C1CC=CCC1C(=O)OCC(F)(F)C(F)F +CCOC(=O)CSc1nnc(C)n1-c1ccccc1 +CCCC1CN(C(=O)C2CCCN(C(=O)C(C)(C)C)C2)CCO1 +O=C(Nc1ccc(-n2ccnc2)nc1)Nc1cccc(Cl)c1 +O=C(Nc1ccc2ncccc2c1)c1ccc(OCC(F)F)nc1 +N#Cc1ccccc1Cn1ccc(=NCc2ccccc2)cc1 +O=C(Cc1ccc(-n2cnnn2)cc1)NC1CC2CC1C1CCCC21 +CC(C)CNC(=O)CC(NC(N)=O)c1cccc(Br)c1 +COCCCCNC(=O)Nc1cccc(Cl)c1N(C)C +Cc1ccc(NC(=O)CCNC(=O)c2ccc(-n3cnnc3)cc2)cc1 +CNC(=O)c1ccc(Cl)c(NC(=O)NCc2ccc(C)s2)c1 +O=C(COC(=O)Cc1ccsc1)NCC1CCCCC1 +COc1cc(C)sc1C(=O)Nc1cccc(Cn2cccn2)c1 +COc1cccc(CNC(=O)c2cc(C)nc(N3CCCC3)n2)c1 +O=C(c1ccncc1Cl)N(CCC(F)(F)F)CC1CC1 +CCOC(=O)CCC1NCCc2ccc(Cl)c(F)c21 +Cn1nccc1CNC(=O)NC1CCN(C(=O)C2CCCCC2)CC1 +O=C(Cn1ccc2ccccc21)NCc1cn(-c2ccccc2)nn1 +Cc1c(C(=O)OCC2CCC(=O)N2)sc2cccc(F)c12 +NS(=O)(=O)NCc1csc(-c2ccccc2)n1 +Cn1cc(C(=O)Nc2ccc(F)cc2Cl)c(C(F)(F)F)n1 +Cc1ccc(CNC(=O)N2CCCC3(CCOC3)C2)cc1 +COCC(=O)Nc1ccc(Nc2cnc3ccccc3n2)cc1 +Cc1nc2nc(C)c3c(=O)n(-c4ccccn4)ccc3n2n1 +O=C(c1cc[nH]n1)N1CC(O)CC1c1ccc(C(F)(F)F)cc1 +COCCN(Cc1cccs1)C(=O)c1ccc(C#N)cc1 +Cc1ccc(NC(=O)CNC(=O)Cc2ccccc2)cc1Cl +O=C1C2CN(Cc3cccs3)CC2CCN1c1cccnc1 +CNc1cc(Cn2ccnc2-c2cccs2)ccn1 +Cc1noc(C)c1S(=O)(=O)N1CCOC(c2ccccn2)C1 +Cc1nc2ccccc2n1CCCNC(=O)NC(C)c1ccncc1 +Cn1c(N)c(C(=O)CN(CCC#N)Cc2ccco2)c(=O)n(C)c1=O +COc1ccc(OC)c(NC(=O)N2CCCCC2C)c1 +Cc1ccc(C(=O)NC2CCN(c3ccc(Cl)cc3)C2=O)c(=O)[nH]1 +CCC(C)N(C)C(=O)Nc1ccc(NC(C)=O)cc1 +COc1ncc(NC(=O)Cc2ccc(F)cc2)c(N2CCCC2)n1 +CN1CC(C(=O)NCC2CCCc3ccccc32)CC1=O +c1ccc(-n2c(SCc3cccnc3)nnc2C2CC2)cc1 +CNc1nc(C(N)=O)c(NC(=O)c2ccccc2F)s1 +CCC(CC)(CC)NC(=O)NCc1cn(-c2ccccc2)nn1 +CC1(C)Cc2cccc(OCC(=O)NCc3ccccc3)c2O1 +COc1ccc(C(=O)Nc2ccc(Oc3cccc(F)c3)cc2)nn1 +COc1cc(OC)c(NC(=O)C2(c3ccccc3F)CC2)cc1F +CCCN(CC1CC1)c1nc2sccn2c1CO +O=C(Cc1ccc(F)c(F)c1)NS(=O)(=O)N1CCCC1 +Cc1cc(C)c(CNC(=O)Cn2cccn2)c(=O)[nH]1 +CCn1c(SCc2ccc(F)cc2)nnc1-c1cnn(C)c1 +O=C(CN1C(=O)COc2ccccc21)NCc1cccs1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)Cn1ccccc1=O +COCCNC(=O)CCc1nnc(-c2cc(C)nn2C)o1 +O=C(c1csc(Cc2ccccc2)n1)N1CCc2ncccc2C1 +CC(C)CNC(=O)NC(C)c1ccc(-n2ccnc2)cc1 +CN(C(=O)c1cc2ccncc2cn1)C1CCCCC1 +O=C(NCc1ccnc(OC2CCCC2)c1)Nc1cccnc1 +Cc1cccc(NC(=O)CNc2cccc(C(=O)N(C)C)c2)c1C +Cn1cn[nH]c1=NC(=O)c1cc(-c2ccccc2)n[nH]1 +C=CCOCC1CCC2C1OCCN2C(=O)c1ccc(OC)cc1 +CCc1c(C(=O)N2CC(C)c3ccccc32)cnn1-c1ccccn1 +Cc1ccc(C)c(C(=O)CCC(=O)OCc2nc(C)no2)c1 +Cc1ccc(C(C)(O)CNC(=O)c2cc(Br)cn2C)o1 +COC(=O)c1ccoc1COC(=O)c1nn(C)c(=O)c2ccccc12 +Cn1c(=O)c2c(ncn2CCNc2ccccc2Cl)n(C)c1=O +COc1cccc(SC(C)C(=O)NCc2ccco2)c1 +CCOc1cccc2c1CCNC2Cc1cccnc1 +CCNS(=O)(=O)c1cc(-c2ccc(N(CC)CC)nn2)ccc1C +CCCOc1c(Cl)cc(C(N)=O)cc1OCC +Cc1cccc(CSc2nnc(CNC(=O)c3ccccc3)o2)c1 +CCC(=O)Nc1ccc(Cl)c(NCc2noc(C(C)C)n2)c1 +CCOC(=O)CNC(=O)c1csc(-c2cnccn2)n1 +CN(C1CCCCC1)S(=O)(=O)c1cccc(F)c1 +CCOC(=O)c1sc(NC(=O)Cc2ccccc2Cl)nc1C +COc1ccc(CCC(=O)N=c2[nH]c3ccccc3[nH]2)cc1 +CC1CCN(c2cc(NC(=O)NC3CCCCC3)ncn2)CC1 +CNS(=O)(=O)c1ccc(C(=O)NCC(O)c2ccco2)cc1 +COCC(O)CN(C)c1cccc(Cl)c1CO +CCOc1ccc(NC(=O)COc2cccc(OC)c2)cc1F +O=C(NCc1nc(-c2ccc(N3CCCC3)cc2)no1)c1ccco1 +CC(C)CCNC(=O)Cn1cc(C#N)c2ccccc21 +O=C(c1scnc1C1CC1)N1CCN(CC2CC2)CC1 +O=C(Nc1cccnc1)c1ccc(-n2cccn2)cc1 +CC(=O)N1CCC(Cc2cc(Nc3cccc(C)n3)ncn2)CC1 +CSc1cccc(NC(=O)NCc2ccnc(OCC3CC3)c2)c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1ccc2c(c1)CCC2 +CC1(C)Cc2sc3c(=O)n(CC(N)=O)cnc3c2CO1 +CCn1cc(C#N)c(=O)n(Cc2nnc(-c3cccs3)o2)c1=O +Cc1c(N)cccc1C(=O)N(CCC#N)Cc1cccnc1 +CCNC(=O)Nc1cc(OCC)c(OCC)cc1Br +C=CCCCN(C)C(=O)NCc1ccc(-n2ccnc2)cc1 +CCNC(=O)c1ccc(CNC(=O)Nc2ccccc2C(C)C)cc1 +COc1cccc(CC(=O)N2CCSc3ccccc32)c1 +C#CCCCOC(=O)c1nn(CC(C)C)c(=O)c2ccccc12 +COc1cccc(OCC(=O)NCc2ccc(C)cc2)c1 +CN1C(=O)C(C)(C)c2cc(S(=O)(=O)NCc3ccccc3)ccc21 +CCOc1cc(C#N)ccc1OCc1ccccc1C#N +COC(=O)CN(C)C(=O)c1cc(OC)c(OC)cc1N +O=C(OCC1CCCO1)C1CCN(C(=O)c2ccoc2)CC1 +CC(c1ccco1)N(C)C(=O)Nc1cccnc1-n1cncn1 +O=C(OCC(=O)N1c2ccccc2CCc2ccccc21)c1cc[nH]n1 +COc1ccc(NC(=O)C2(c3ccccc3)CCC2)c(OC)c1 +CCC(=O)N(Cc1cc2ccccc2[nH]c1=O)c1ccccc1 +CN(CC(=O)Nc1c[nH]cc(Br)c1=O)c1ccccc1 +CCCc1nnsc1C(=O)NC1CC(O)C(CO)C1 +O=C(NC1CCN(C(=O)c2ccco2)CC1)c1ccccc1F +COc1cc(Cl)ccc1C(=O)Nc1cc(C)nn1C +COCCN(c1ccccc1C(C)O)C(C)C1CC1 +COc1ccc(OCC2CCCN(C(=O)CCn3cncn3)C2)cc1 +CC(C)CC(=O)OCCn1nc(-c2ccccc2)cc1N +COc1cccc(C(CNC(=O)c2cn(C)nn2)OC)c1 +CCC1CCC(CNC(=O)Cc2csc(-c3nc[nH]n3)n2)CC1 +O=C(NCC1CCC1)c1ccc(Cl)c2cccnc12 +CCOCC1CN(C(=O)c2cccc(C)n2)Cc2cnn(C)c21 +O=C(Nc1ccccc1O)c1cccc(OC(F)F)c1 +COc1ccc(OC)c(C(=O)Nc2cccc(CO)c2)c1 +N#CCn1nc2ccc(SCc3ccc(Cl)cc3)nn2c1=O +COc1ccc(OCC(=O)Nc2onc3c2CCCC3)cc1 +Cc1ccc(CNC(=O)CCc2conc2-c2ccc(F)cc2)o1 +COc1cc2ccccc2cc1C(=O)NCc1c(C)cc(C)[nH]c1=O +CC(CC#N)N(C)C(=O)Nc1ccc(OCc2ccccc2F)cc1 +CNC(=O)c1ccc(Cl)c(NCCOc2ccc(C#N)cc2)c1 +COc1ccc(-c2cncc(-c3cc(NCCC#N)nc(C)n3)c2)cc1 +COCC(=O)N1CCc2ccc(S(=O)(=O)N3CCCC3)cc21 +Nc1c(Nc2cccnc2)ncnc1Oc1cccnc1 +CC(C)S(=O)(=O)NC(c1ccccc1)C1CC1 +COCCCNc1nc(C)nc2sc3c(c12)CCC3 +CCCCNC(=O)C1CCC(C)N(S(=O)(=O)N(C)C)C1 +Cc1ccnc(NC(=O)C2CC(=O)N(c3ccc(C(C)C)cc3)C2)c1 +COc1ccc(CCNC(=O)CCn2cccn2)cc1 +CCCCOC(=O)CN1C(=O)COc2cc(CO)ccc21 +O=C(Cn1cccn1)Nc1ccc(-n2cnnn2)cc1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)OCC1CCC(=O)N1 +Cc1cc(-c2ccc(S(=O)(=O)N3CCCC3)cc2)on1 +COc1cc(C(=O)NC(C)(C)C#N)ccc1OC1CCCC1 +COCCCC(=O)N1CC(c2ccc(F)cc2)CC1C +O=C(NCc1cc2ccccc2[nH]1)NCC1CN2CCCCC2CO1 +NC(=O)COc1ccccc1C(=O)Nc1ccc2c(c1)COC2 +O=C(NCc1ccccn1)c1ccc(N2CCCCC2)cc1 +COCc1cccc(CNC(=O)NCCC(C)(C)C)c1 +CC(=O)Nc1ccc(O)c(C(=O)NCc2ncn(C)n2)c1 +C#CCNC(=O)CNC(=O)c1cccc(NC(=O)C2CCCO2)c1 +N#CCCCOc1cccc(NC(=O)c2cn3cccnc3n2)c1 +COC(=O)c1sc(NC(=O)CCc2ccccc2)nc1C +CC1Cc2cc(C(=O)N3CCCCCC3)ccc2N1S(C)(=O)=O +Cc1ccc(NC(=O)NCCNc2ccc(-n3cccn3)nn2)cc1 +O=C(C1CCCO1)N1CCOc2c(O)cc(-c3cccnc3)cc2C1 +CN(Cc1ccccc1)C(=O)COc1cccc(N2CCCC2=O)c1 +O=C(CCn1cc(Cl)cn1)Nc1ccc(Cl)cn1 +CCOC(=O)N1CCC(NS(=O)(=O)N2CCC(C)CC2)CC1 +CN(Cc1cccnc1)C(=O)c1cccc(NC(N)=O)c1 +CCn1ccc2cc(NC(=O)c3cc(-c4cccnc4)on3)ccc21 +CCC(C)(C)NC(=O)c1c(-c2ccccc2)noc1C +CNC(=O)c1cccc(NC(=O)C(C)OC)c1C +COc1cccc(C(=O)c2ccc(OC(C)C)cc2)n1 +COc1ccc(Cl)cc1N(C)C(=O)c1scnc1C1CC1 +O=c1[nH]c(NC2CCCCC2O)nc2c1cnn2-c1ccccc1 +C#Cc1cccc(NC(=O)NCC(C)(C)c2ccncc2)c1 +O=S(=O)(C1CCCCC1)N1CCC(c2cc[nH]n2)C1 +CCOC(=O)c1cc2ccsc2n1CC(=O)NCc1cccnc1 +CCCCN(CCO)C(=O)c1nc2nc(C)cc(C)n2n1 +CC(C)CC(c1nc(-c2ccsc2)no1)N1CCCCC1=O +COc1ccc(C(C)C)cc1CCN(C)C(=O)CO +COc1ccc(NC(=O)CCc2ccc3nc[nH]c3c2)c(OC)c1 +Brc1ccc2c(c1)OCC1(COC1)CO2 +Cn1cnnc1CCNC(=O)CC12CC3CC(CC(C3)C1)C2 +C=CCNC(=O)Cn1c(CNC(C)=O)nc2ccccc21 +N#Cc1ccc(NC(=O)COc2ccc(-n3cnnn3)cc2)cc1 +O=C(Nc1cccc(OCCn2cncn2)c1)c1cc[nH]n1 +O=C(CN1CCCCC1c1cccnc1)c1ccccc1 +COc1ccc(C23CCC(=O)N2c2ccccc2O3)cc1 +Cn1cc(CNC(=O)c2[nH]c3ccccc3c2Cl)cn1 +Cn1cc(C2CC2C(=O)OCc2csc(-c3ccccn3)n2)cn1 +O=C(Cn1nc(-n2cccn2)ccc1=O)NC1CCCCC1 +COc1ccc(Br)cc1-c1nc(C)co1 +CCc1cccc(NS(=O)(=O)c2ccc3c(c2)CC(=O)N3)c1 +Cc1cc(S(=O)(=O)CC(C)C#N)ccc1Cl +N#CC1(C(=O)N2CCC(OCCc3ccccc3)CC2)CCCC1 +CCCN(CCO)C(=O)Nc1ccccc1CC +COCCc1nc2nc(N)c(C(N)=O)cc2c(=O)[nH]1 +CC1CCC(N(C)C(=O)C2CC(=O)N(C)C2c2cccnc2)CC1 +Cc1ccc(N2CCCC2=O)c(C(=O)NCC2CCCO2)c1 +COc1ccc(C(=O)NCCNC(C)=O)cc1N +Cc1cc(CN(C)C(=O)CCCSc2ccccc2)no1 +COC(=O)c1cc(NC(=O)c2ccccc2F)ccc1Cl +CCOc1ccccc1C1C(C#N)C(=O)Nc2nc3ccccc3n21 +CN(C(=O)C1CC2C=CC1C2)c1ccc(Cl)cn1 +CC(C(N)=O)n1ccnc1Cc1ccc(Cl)c(Br)c1 +Cc1nc(NCCC(C)(C)C)sc1C(=O)N(C)C +COc1ccc(C)cc1NC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1ccccc1C(C#N)N(C)C(=O)c1cccc(F)c1 +Cc1c[nH]c(=NC(=O)c2noc3c2CCCCC3)[nH]1 +O=C(Nc1ccc(OCC(F)(F)F)nc1)c1ccccn1 +CC(=O)NC(C(=O)OCC(=O)Nc1cccc(C)c1)C(C)C +COc1c(NC(=O)Nc2ccc(-n3cccn3)c(F)c2)c(C)nn1C +O=C(CCc1cccc(Cl)c1)Nc1nc[nH]n1 +Cc1cccc(-c2nn(-c3ccc(F)cc3)cc2C(N)=O)c1 +CCn1c(CCNC(=O)c2cnc(C)[nH]c2=O)nc2ccccc21 +O=C(NCCn1nc(-c2ccccn2)cc1C1CC1)c1cccs1 +CC(CC(=O)OCC(=O)N1CCCC1)c1cccc(C(F)(F)F)c1 +CCOCCS(=O)(=O)c1nccn1-c1cccc(OC)c1 +Cc1cc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)n(C)n1 +Cc1ccccc1C(C#N)NS(=O)(=O)c1c(C)noc1C +CNC(=O)c1ccc(NC(=O)CSc2cc(C)ccc2C)cc1 +Cc1cc(C)n(CC(C)CNC(=O)Nc2cccc(OCC#N)c2)n1 +CCc1ccc(C(=O)CSc2nnnn2C)cc1 +Cc1ccc(CNC(=O)c2nnc(CN3CCC(O)CC3)s2)cc1 +NC(=O)CCSc1nc2ccccc2c(=O)n1C1CCCCC1 +CNC(=O)Cc1csc(NC(=O)CCc2nc3ncccc3[nH]2)n1 +COc1ccc(N2CCN(C(=O)C(C)n3cc(C)cn3)CC2=O)cc1 +CC(C)CN(C(=O)CNc1c(F)cccc1F)C1CC1 +CC(N)c1cc(=O)[nH]c(Cc2cccc(Cl)c2)n1 +CCN(CC)C(=O)NCCc1nc2ccccc2s1 +N#Cc1c(F)cccc1N1CCC(Oc2ccccn2)CC1 +Cc1ccccc1Cn1c(=O)oc2cccc(N)c21 +C#CCNC(c1cccc(OC)c1)c1cccc(OC)c1 +CN(CCc1ccc(F)cc1)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +Cc1cc(N2CC(C)C(O)(C3CCC3)C2)nc(N2CCOCC2)n1 +Cc1nccn1-c1ncccc1NC(=O)CCOCC(C)C +Cc1cnc(NC(=O)c2ccc(N(C)C)nc2)s1 +CN(CCC#N)C(=O)c1ccc(S(=O)(=O)NC(C)(C)C)o1 +O=C(CSc1ccc(F)c(F)c1)Nc1cccc2cnccc12 +COc1ccccc1N1CCN(C(=O)CSc2ccncc2)CC1 +CCOC(=O)c1ccc(NC(=O)c2sc(C)nc2C)cc1 +N#Cc1ccc(C(=O)NC2CCN(c3ccccc3)C2=O)cc1 +CCN(Cc1ccccn1)C(=O)Nc1ccc(SC)c(F)c1 +CCn1nc(C)cc1C(=O)Nc1ccn(CC#N)n1 +CC(=O)N1CCN(C(=O)C(C)S(=O)c2ccc(C)cn2)CC1 +CC(C)NC(=O)NCc1coc(-c2cccs2)n1 +CC(C)Cn1c(N)c(C(=O)CSc2ncn[nH]2)c(=O)n(C)c1=O +N#Cc1nc(N)n(Cc2nn(-c3ccccc3)c3c2CCC3)c1C#N +CC(C)NC(=O)CN(C)C(=O)c1cccc(Cl)c1 +CN(c1ccc(F)c(F)c1)S(=O)(=O)c1cccc(N)c1 +COC(=O)Cn1cnc2c(-c3ccc(Cl)cc3)csc2c1=O +O=C(COc1nnc2ccccn12)Nc1ccc(Cl)cc1Cl +COC(=O)c1cc(CN2CCN(c3nc(C)ns3)CC2)c[nH]1 +COc1ccc(CN(C)C(=O)c2cc3c(s2)CCCC3)cc1OC +CCS(=O)(=O)N(Cc1cccc(F)c1)c1ccc(C(C)=O)cc1 +COc1ccc(C2NCCc3c2ccc(C)c3F)cc1O +CCC(CC)NC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +CCC(CC)N(CCO)C(=O)c1cccc(N)c1 +COc1ccc(Br)cc1-c1nc(C)c(C)o1 +Cc1ccc2c(c1)CCCN2S(=O)(=O)N(C)C +CC(CCc1ccccc1)NC(=O)Cc1nnc(-c2cccs2)o1 +COC(=O)c1ccccc1NC(=O)c1cccc(-n2cccn2)c1 +CC(C)CCNC(=O)CS(=O)c1ncccc1N +Cc1nc(NC(=O)N2CCCC2c2cccn2C)oc1C +CCOCC1CCCN(C(=O)c2cccc(Cl)c2Cl)C1 +CCOc1ccc(-c2noc(-c3cnc(C)[nH]c3=O)n2)cc1 +CC(=O)C1(c2ccccc2)CCN(C(=O)c2c[nH]c(=O)cn2)CC1 +CCCCN(C)C(=O)c1cc2c(cc1O)OCO2 +CC(C)N(CCO)S(=O)(=O)c1cccc(Br)c1 +CC(C)(C)CC(NC(=O)NCc1cscn1)c1ccc(F)cc1 +N#Cc1cnn(C(=O)CCc2nc3ccccc3s2)c1N +CCC(CC)N(C)C(=O)c1ccc(Cl)c(N)c1 +COc1ccccc1OCC(=O)Nc1ccc(C#N)c(Cl)c1 +CCn1nc(C(C)C)cc1C(=O)NC(C#N)C(C)(C)C +Cn1cc(N2CCN(Cc3ccc(-n4cncn4)cc3)CC2=O)cn1 +CCCCS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +CCc1ccc(C(c2cccnc2)N(CC)C(=O)C2CCOC2)cc1 +Cc1c(C(=O)NCc2cccs2)cn2nc[nH]c(=O)c12 +CCCCS(=O)(=O)N1CCN(c2cc(NCC)nc(C)n2)CC1 +Cc1cc(C(=O)NCCCNc2cccnc2)c2ccc(F)cc2n1 +Cc1ccc(C)c(C(=O)CN2C(=O)c3ccccc3CS2(=O)=O)c1 +Cn1ccc(C(=O)Nc2cc(Cl)cc(Cl)c2)n1 +Cc1ccsc1C(=O)Nc1ccc(N)cc1Br +Nc1cccc2c1CCN(C1COc3cc(O)ccc31)C2 +CC(C)Cn1c(CCCO)nc2cc(Cl)ccc21 +O=C(NCC(=O)N1CCCCC1)NCc1cccc(C(F)(F)F)c1 +Cc1occc1C(=O)N1CCN(C(=O)CCc2ccc(F)cc2)CC1 +CN(C)S(=O)(=O)c1cccc(C(=O)N2CCC(C(N)=O)CC2)c1 +O=c1[nH]nc(C2CCN(c3ncccn3)CC2)n1Cc1ccccc1 +COc1cccc(C(=O)NC(C)C(=O)N2CCCCC2)c1 +COCC1CCCN(C(=O)c2ccc(N(C)CCC(C)(C)O)nc2)C1 +CCCOC(=O)c1cn(C)nc1-c1cccs1 +CCn1nnc2cc(C(=O)Nc3c[nH]ccc3=O)ccc21 +Cc1noc(C)c1C(C)NC(=O)C(C)Cc1ccccc1 +N#Cc1ccc(Cn2nc(-c3nccc4ccccc34)oc2=O)cc1 +NC(=O)CCNC(=O)C(c1ccccc1)c1ccccc1 +CSc1ccsc1C(=O)Nc1ccc(C(=O)NC(C)(C)C)cc1 +COc1ccc(Cl)cc1C1CCn2nc(N)nc2C1 +Cc1csc(Cc2noc(-c3sccc3N)n2)n1 +COc1ccc2nc(NC(=O)Cn3ccc(=O)[nH]c3=O)sc2c1 +COc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(C)=O +O=C(c1c(F)cccc1F)N(Cc1ccco1)Cc1cccs1 +Cc1csc(=O)n1CCC(=O)Nc1ccc(-n2cccn2)c(F)c1 +COc1ccc(S(=O)(=O)N2CC(C(N)=O)CCC2C)cc1Cl +CCOc1ncccc1C(=O)N1CCC(C(N)=O)c2ccccc21 +CC(CO)CNS(=O)(=O)c1ccccc1Cl +O=C(COC(=O)C1CC2C=CC1C2)c1ccccc1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)NCC(C)N1CCOCC1 +COc1ccccc1CN(c1ncnc2sccc12)C1CC1 +Cc1noc(C)c1CCCNC(=O)NCC(C)(C)C(N)=O +Fc1ccc(-c2nc(-c3ccc(-n4cccn4)nc3)no2)c(F)c1 +CC(C)CNC(=O)COC(=O)c1cc(=O)[nH]c2ccccc12 +COC(=O)C(C)(C)c1ccc(NC(=O)NCc2cnn(C)c2C)cc1 +COC(=O)c1ccc(CN(C)Cc2cn(-c3ccccc3)nc2C)cc1 +O=S(=O)(NCc1ccccn1)c1ccc(Br)cc1F +CC(C)CNC(=O)c1ccccc1NC(=O)C(C)NC(N)=O +CC(C)NC(=O)N(C)CCCOc1ccc(S(C)(=O)=O)cc1 +Cc1cc(C)cc(C(C)NC(=O)NCc2cn(-c3ccccc3)nn2)c1 +OC(COc1cccc2ccccc12)Cn1nnc(-c2cccnc2)n1 +O=C1CN(C(=O)NCCCN2CCCC2=O)CCN1 +CCN1C(=O)Cc2cc(C(=O)NCc3ccccc3C)ccc21 +CN(Cc1ccccc1)C(=O)CN1CCN(c2ccccc2)C1=O +COCCCN1CC2(CCCN(c3ncc(F)cn3)C2)CCC1=O +CCCCNC(=O)CN1CCN(Cc2ccc(F)cc2Cl)C1=O +O=C(Cc1csc(N2CCCC2=O)n1)Nc1ccccc1F +Cc1nc2c(cnn2C(C)C)c(C)c1CCC(=O)Nc1ccn(C)n1 +CC(NC(=O)c1ccc(F)cc1Br)C(=O)N1CCCC1 +Cc1ccc(C)c(OC(C)C(=O)NCc2cc(=O)[nH]cn2)c1 +Cc1ccc2ncn(Cc3csc(-c4cnn(C)c4)n3)c(=O)c2c1 +O=C(Nc1ccc(F)cc1F)c1cc(-c2cccnc2)on1 +Cc1cnc(NC(=O)C2CCN(c3ccc4nncn4n3)CC2)s1 +CCNC(=O)N(Cc1ccc(Cl)cc1)Cc1cccnc1 +CCOc1cc(NC(=O)c2c(F)cccc2F)ccc1OC +CC(C)n1cc2c(n1)C(NC(=O)c1ccccn1)CCC2 +O=C(NCc1ccc(C(F)(F)F)cc1)c1cc2c(cn1)OCC2 +Cc1nc(C(=O)NCCC(=O)OC(C)C)cs1 +CCNC(=O)COc1cccc(C(=O)N(C)CC)c1 +CCn1cc(CN(C)C(=O)Cn2cc(C)c(N)n2)cn1 +Cc1ccccc1CC(=O)N1CCN(Cc2ccccc2)C(C#N)C1 +CC(C)c1ccc(NC(=O)Cn2nc3n(c2=O)CCCCC3)cc1 +CC(C)Cn1ncc(C(=O)Nc2ccc(S(C)=O)cc2)c1C1CC1 +Cc1ccncc1NC(=O)NCC(O)c1ccc2ccccc2c1 +O=C(CSc1nccc2ccccc12)N1CCCC1 +CCOC1CC(NC(=O)C(C)n2cncn2)C12CCCCC2 +O=C1CC2(CCN(C(=O)c3ccc4[nH]ccc4c3)CC2)CN1 +O=C(COC(=O)C1CC1)NCc1ccc2c(c1)OCO2 +Cc1ncc(CNC(=O)NCc2ccc(OCC(C)C)cc2)s1 +Cc1ccc(O)c2c1C(c1ccc(O)cc1)NCC2 +O=C(CCSc1ccccn1)NC1(c2nccs2)CCCC1 +Cc1cccc2c1NC(=O)C2(O)CC(=O)c1ccc2c(c1)OCO2 +Cc1cc2c(n1Cc1cccc(Cl)c1)CCCC2O +Cc1ccccc1C1CC(C)N(C(=O)c2ncoc2C2CCCO2)C1 +O=S(=O)(c1ccc(F)c(F)c1F)N1CC(O)C1 +COCCOCC(=O)NC(C)c1ccc2c(c1)CCC(=O)N2 +Cc1nnc2sc(C34CC5CC(CC(C5)C3)C4)nn2c1=O +Cc1ccnc(N2CCC(C(=O)NCc3cccc(F)c3)CC2)n1 +O=C(COc1ccc(F)cc1)NC1CCC(O)CC1 +Cc1ccc2c(C(=O)NCCCN3CCOCC3)nccc2c1N +COc1cccc(F)c1-c1cccc(-n2cnnc2)c1 +CN(CCCc1n[nH]c(N)c1C#N)C(C(N)=O)c1ccccc1 +CN(Cc1ccncc1)C(=O)C1CCCN(C(=O)OC(C)(C)C)C1 +CNc1snc(C)c1C(=O)N1CCCC1CC(=O)c1cnn(C)c1 +CCC(CC)C(=O)NCC(O)c1ccc(C)cc1C +CCOC(=O)C(N)c1c(F)ccc2cn(C)nc12 +CCn1cc(C(=O)NCc2ccc(Cl)cc2OC)cn1 +CC(C)C(=O)N1CCC2(CC2C(=O)NCc2cccs2)C1 +O=C(NCCn1nc(-n2cccn2)ccc1=O)c1ccc(F)cc1F +COc1ccc(CC(=O)N2CCN(Cc3cccnc3)CC2)cc1F +CCCOc1ccc(-c2cnn(CCC)c(=O)c2N)cc1 +OC1=Nc2ccccc2C(c2ccc(Br)cc2)=NC1 +COC(=O)N(C)c1ccc(NC(=O)Nc2ccncc2)cc1 +O=C(NCc1cn2ccccc2n1)c1cc(-c2ccc(F)cc2)[nH]n1 +O=C(NCCOCCO)Nc1cccc2ccccc12 +COc1ccccc1CNC(=O)CSc1nc(-c2ccn[nH]2)n[nH]1 +Nc1nc(SCc2nc(-c3cccc(Cl)c3)no2)n[nH]1 +CC(=O)NCCNC(=O)NC(C)Cc1ccccc1F +CCc1ccc(S(=O)(=O)NCc2ccc(OC)cc2)cc1 +Cc1cc(C)nc(Nc2noc(-c3ccc(F)cc3)n2)n1 +Cn1cc(C(=O)Nc2ccccc2Cl)ccc1=O +CCNS(=O)(=O)c1cccnc1Nc1cccc(F)c1 +Cc1ccc(Cl)cc1NC(=O)c1cnc(N2CCOCC2)nc1C +O=C(Cc1cccc(F)c1F)NCCc1ccccc1F +CC(=O)Oc1ccc(C(=O)Nc2c(C)cc(C)cc2C)cc1 +O=C(CCSc1ccccn1)Nc1ccc(N2CCCCC2)cn1 +CCCn1c(NC(=O)C2CC(=O)N(C3CC3)C2)nc2ccccc21 +CCNC(=O)c1cccc(S(=O)(=O)Nc2ccc(F)cc2)c1 +CS(=O)(=O)N1CCC(C(=O)NC2CCOc3ccccc32)CC1 +COc1cc(Br)cc(NC(=O)N2CCC(O)C2)c1 +CC(C)CC(NC(=O)CS(=O)(=O)c1ccccc1)c1ccccc1 +CC(NC(=O)c1ccccn1)c1ccc2c(c1)OCCO2 +COc1ccc2[nH]cc(CC(=O)N(CCC#N)CCC#N)c2c1 +Cc1cccc(NC(=O)c2cc3c(=O)n4cc(C)ccc4nc3n2C)c1 +O=C(CNC(=O)c1cccs1)NCC1(c2ccccc2)CCC1 +COCCNC(=O)c1cnc(N2CCCC2)nc1N +COC(=O)CC(NC(=O)CC1CCCC1)c1ccc(Cl)cc1 +COc1cccc(S(=O)(=O)N2CCC3(CC(OC)CO3)C2)c1 +CN(C)C(=O)CN1CCN(c2ccc(F)cc2)C1=O +NC(=O)C(Cc1ccccc1)NC(=O)c1cccnc1 +Cc1cnc(C(=O)N2CCCN(Cc3nccn3C(C)C)CC2)cn1 +CSc1nn(-c2ccccc2)cc1C(=O)N1CCCC1 +COc1ccc(CCC(=O)NC(C)c2c(C)noc2C)cc1OC +CN(Cc1ncc[nH]1)C(=O)c1cnc(-c2ccccc2)nc1 +N#Cc1cc(NC(=O)NCc2nc3ccccc3s2)ccc1F +NC(=O)c1ccsc1NC(=O)c1ccc2ccccc2c1 +CC(NC(=O)c1cnccn1)c1nc2cccnc2n1C(C)C +CC(C)CNC(=O)c1ccc(NC(=O)N2CCNC(=O)C2)cc1 +CC(C)OCc1cccc(CNC(=O)NC2C3CCOC3C2(C)C)c1 +Cc1cccc(OCCC(=O)NC(C)c2ccccn2)c1 +COc1ccc(CN(C)C(=O)COc2ccccc2Cl)c(OC)c1 +O=C(Cc1nc2ccccc2c(=O)[nH]1)c1c[nH]c2ccccc12 +O=C(CSc1ncn[nH]1)Nc1ccc(OC(F)F)c(Cl)c1 +CCOc1ccc(C(=O)CSc2ccc(N)cc2)cc1 +CCn1cc2c3c(cccc31)CN(C(=O)NC(C)C(=O)OC)CC2 +CCCCOC(=O)C(C)Sc1nnc(C)s1 +COCCNC(=O)Nc1cc(Cl)c(OC)c(Cl)c1 +COC(=O)c1cc(COc2ccccc2)nc(N(C)C)n1 +CNC(=O)NCC(=O)N1CCCCC1c1nc2ccccc2s1 +CCCCOCC(=O)Nc1cc(OC)ccc1F +CC(=O)Nc1cccc(NC(=O)N(C)Cc2ccoc2C)c1C +Cc1ccc(-c2nnc(NC(=O)c3ccc(=O)n(C)c3)s2)c(C)c1 +Cc1cc(N)c2onc(CC(=O)NCc3ccco3)c2c1 +NC(=O)c1ccc(NC(=O)c2cc(F)cc(F)c2)cc1 +Cc1csc(CNC(=O)NC2CCN(c3ncccn3)CC2)n1 +CCOCCOC(C)C(=O)N1CC(C)OC(C)(C)C1 +c1ccc(CSc2nc(C3CCCC3)n[nH]2)cc1 +C#CCC(OC(=O)c1ccc(CNC(C)=O)s1)c1ccccn1 +COCc1ccccc1CNC(C)C(=O)NC(C)C +Cc1ccccc1C1CC(C)N(C(=O)c2cnn(C)c2C)C1 +NC(=O)COC(=O)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 +COc1ccc(C(C#N)NC(=O)c2ccc(C)cc2)cc1OC +Cc1ccc(C(=O)Nc2c(N)ccc(C)c2C)s1 +O=C(COC(=O)Cc1ccccc1)Nc1ccc(F)cc1 +O=C(Nc1ccccc1Cl)c1cc(-c2ccccn2)[nH]n1 +Cn1cc(C(=O)Nc2c(F)c(F)c(F)c(F)c2F)cn1 +O=C(CNc1cccc(Cl)c1N1CCOCC1)N1CCCCC1 +CC(=O)c1c(C)nc(Nc2nc3ccccc3o2)nc1C +CCc1ccc(C(=O)NCc2cccc(CO)c2)s1 +COc1cc(OC)cc(C(=O)Nc2ccc(N)nc2)c1 +CCn1cncc1CN1CCc2nc3sccc3c(=O)n2CC1 +Cc1csc(CNc2ccc(OCCO)nc2)n1 +Cc1cc(F)ccc1S(=O)(=O)Oc1ccc(-n2ccnc2)cc1 +Cc1c(C(=O)N2CCCCC2)c(C(F)(F)F)nn1-c1ccccc1 +CC(C)c1cc(C(=O)N2CCC(Oc3ccccc3Cl)CC2)on1 +COc1ccc(S(=O)(=O)Nc2nccc(C)n2)cc1OC +CCc1nn(CCC(N)=O)c(=O)c2cc3ccsc3n12 +Cc1ccn(Cc2ccc(Br)cc2)c(=O)c1 +CCCC(C)C(=O)Nc1ccc(F)c(NC(C)=O)c1 +CCOC(=O)Cn1c(-c2ccco2)nc2ccccc21 +CCC(=O)Nc1ccc2c(c1)CC(C(=O)NCCOC)CO2 +Cc1ccc2nc(C3CN(S(C)(=O)=O)C3)[nH]c2c1 +Cc1cc(CN(C)C(=O)c2cc(Br)ccc2F)no1 +COCCCCS(=O)(=O)NC1CCC(C)CC1C +Fc1cccc(-c2nc(Cn3nnc(-c4ccsc4)n3)co2)c1 +COc1ccc(Cl)cc1C(O)CNc1ccc(C#N)cc1 +CCNC(=O)NCCOC(=O)c1sc(C)cc1OC +CCN(C(=O)Cn1ccc(C)cc1=O)c1ccccc1 +CCCN(CCc1ccccn1)C(=O)C1CCN(C(C)=O)CC1 +CN(C1CCCCC1)S(=O)(=O)N1CCN(Cc2ccco2)CC1 +O=C(Cc1ccccc1Br)N(Cc1ccccn1)C1CC1 +CCOC(=O)C1CCN(C(=O)CNc2cccc(C)c2C)CC1 +Cc1noc2nc(-c3cccs3)cc(C(=O)OC(C)C(N)=O)c12 +CNS(=O)(=O)c1ccc2c(c1)CCN2C(=O)c1cccc(OC)c1 +Cc1nn(-c2ccc(F)cc2F)c(C)c1CN(C)C(C)CC#N +C#CCN(CC#C)Cc1ccccc1N1CCOCC1 +c1ccc(CCc2nnc3n2NC2CCCC2S3)cc1 +CC(NC(=O)N1CCN(c2cc(C#N)ccn2)CC1)c1ccccn1 +COc1c(Cl)ccc2c1C(C1CCOCC1)NCC2 +Cc1ccc(C(=O)CCC(=O)N(C)Cc2ccc(F)cc2)cc1 +CCCC(C)c1nnc(NC(=O)c2ccccc2-n2cncn2)s1 +CNc1nc(C(=O)Nc2ccc3c(c2)COC3)cs1 +Cc1cc2nc(C)c(CCC(=O)NCC(C)C)c(C)n2n1 +CS(=O)(=O)NC1CCN(C(=O)c2cc(O)nc3ccccc23)CC1 +COC(=O)CCC(=O)Nc1cccc(N2CCCC2=O)c1 +CCCN(Cc1ccc(C#N)cc1)Cc1nc2ccccc2[nH]c1=O +CCC1CN(C(=O)c2c[nH]c(C(C)C)n2)CC1N1CCOCC1 +O=C(c1ncc(F)cc1F)N1CCC(OCc2cccnc2)CC1 +Cc1ccccc1CNC(=O)CSc1nc(-c2cccs2)n[nH]1 +O=C(Nc1cnn(-c2ccccc2F)c1)N1CCc2ccccc2C1 +Fc1cccc2ncnc(NCCc3cnccn3)c12 +CC(=O)N1CCN(C(=O)CCNC(=O)CCc2ccccc2)CC1 +CCCc1nc(CNC(=O)C2COc3ccccc3O2)cs1 +Cc1ccc(-c2n[nH]c(SCc3cccnc3)n2)cc1 +O=C(NCc1ccccc1)c1cc(-c2ccc3c(c2)OCO3)on1 +CCn1c(=O)c(SCC(=O)NC)nc2ccccc21 +COc1ccc(CC(=O)N2CCOCC2C2CC2)cc1F +Cc1noc(CCC(=O)Nc2cnn(-c3ccccc3F)c2)n1 +CC(=O)Nc1nc(CN2CCN(c3ccccc3)CC2)cs1 +COCC(C)NC(=O)c1cc(-c2ccc(OC)c(OC)c2)on1 +CC(Oc1cccc2c(N)cccc12)c1cccnc1 +O=C(NCCCN1CCc2ccccc21)c1ccc(-n2ccnc2)nc1 +Cc1cc(F)cc(Br)c1S(N)(=O)=O +COc1cc(OC)cc(C(=O)NC(C#N)c2ccc(F)cc2)c1 +OCc1c(-c2ccccn2)nc2sc(-c3ccco3)nn12 +COc1ccnc(N2CCC(C(=O)N3CCc4ccccc43)CC2)n1 +CC1CN(C(=O)C2CC(=O)N(c3ccc4c(c3)OCO4)C2)CCO1 +Nc1cc(F)ccc1NC(=O)CSc1cccs1 +CCN(CC)C(=O)CNC(=O)NCCc1ccccc1C +Nc1cccc(-c2csc(Cc3ccncc3)n2)c1 +COc1cccc(C(=O)NCC2Cc3cc(F)cc(F)c3O2)c1 +CCOC1CCCN(C(=O)NCC(C)(C)c2ccncc2)C1 +CC(C)c1cccc(N(C)C(=O)Cn2ccc(=O)[nH]c2=O)c1 +CCc1ccc2c(c1)c1nnc(SCC#N)nc1n2C +CN(C)c1cc(C(F)(F)F)nc(N(C)CC(=O)NC(C)(C)C)n1 +Cc1ccc(NC(=O)N2CCOCC2)cc1S(C)(=O)=O +COC(=O)CC1Nc2cc(C(F)(F)F)ccc2NC1=O +Nc1cnn(CC(=O)Nc2cccc(C(F)(F)F)c2)c1 +O=C(NCc1cccnc1)c1ccc2nc[nH]c(=O)c2c1 +O=C(CCCn1c(=O)oc2ccccc21)Nc1cccc2ncccc12 +CNC(=O)CN1C(=O)C(C)Nc2cc(F)ccc21 +CCn1cc(C(=O)NCC(C)O)c(=O)c2c(N)cccc21 +CC(CO)CNC(=O)NCc1cccc(NC(=O)C2CCCC2)c1 +CN(C)C(=O)C(Cc1ccccc1)NS(=O)(=O)c1ccccc1 +CCOc1ccc(OCC(=O)Nc2cc(N3CCCC3)ncn2)cc1 +CC(=O)NCCNC(=O)c1nc(-c2ccccc2)oc1C +CCCC(C)CS(=O)(=O)N1CCOCC1c1ccc(CC)o1 +OCCc1cnn(Cc2nnc(-c3cccs3)o2)c1 +CC(=O)N1CCN(C(=O)CNC(=O)OC(C)(C)C)CC1 +COc1ccc(C(=O)C2CCN(C(=O)C(C)C)CC2)cc1 +Cc1n[nH]c(SCc2cccc(OCC(N)=O)c2)n1 +CCSc1nc2nccc(-c3cccs3)n2n1 +Cn1nc(C(=O)Nc2sccc2C(N)=O)ccc1=O +Nc1nc(N2CCC(OCc3ccccc3)CC2)c2nc[nH]c2n1 +COc1ccc(-c2nc(C3CCOC3)no2)cc1N1CCOCC1 +Cc1ccc(C(=O)N2CCC(c3c[nH]c4ncccc34)CC2)c(O)c1C +COc1c(C)cnc(CNC(=O)NC2c3ccccc3CC2O)c1C +COc1ccccc1S(=O)(=O)C(C)C(=O)N1CCCCCC1 +N#CC(C(=O)CCOCc1ccccc1)c1ccc2ccccc2n1 +CN(C)C(=O)N1CCC2(CCOCC2NS(C)(=O)=O)CC1 +CS(=O)(=O)Nc1ccc(-c2ncccc2Cl)cc1 +CC(C)CN1CCOC(CNC(=O)Nc2ccccc2)C1 +Cc1n[nH]c(C)c1NC(=O)Nc1cccc(C#Cc2ccccn2)c1 +COC1CCC(c2cc(Cl)ccc2C)n2nc(N)nc21 +O=C(NCc1nnnn1C1CCCCC1)C1CCCCC1 +Cc1csc2ncc(C(=O)N(C)Cc3ccccc3)c(=O)n12 +Cc1cc(C)n(-c2ccc(NC(CCO)c3cccs3)nn2)n1 +Cc1nc(CC(=O)NCc2n[nH]c3c2CCCCC3)cs1 +COc1ccc(-c2cccc(C(C)=O)c2)c(OC)c1OC +N#Cc1c(N2CCOCC2)ccnc1N1CCCC1 +CS(=O)(=O)N1CCC2C(CCC(=O)N2CCc2ccccc2)C1 +CCN(CC)C(=O)C(C)n1c(=O)cc(C)c2ccccc21 +COCCCNC(=O)C1CCN(C(=O)NC2CC2)CC1 +Nc1ccc(F)c(F)c1N1CCc2sccc2C1 +CCN(c1ccc(C(=O)Nc2ccc3oc(=O)[nH]c3c2)cc1)C(C)C +CCc1cccc2c(C(C)=O)cn(CC(=O)NCc3ccccc3)c12 +COc1ccc(C)cc1NC(=O)C1CCN(c2cn[nH]c(=O)c2)CC1 +Cc1ccccc1OCC#CCNC(=O)c1cccn(C)c1=O +Cc1cc(C(=O)N2CCCCC2C(N)=O)c2c(C)nn(C)c2n1 +Cc1ccc(C(O)CCC(=O)NCc2cccnc2)cc1 +CN(CCC(F)(F)F)C(=O)c1cccc(OCC(F)F)n1 +Cc1nc(-c2nc[nH]n2)sc1C(=O)OCc1ccc(F)cc1 +CCNC(=O)CNC(=O)Nc1cccc(Cl)c1N(C)C +CCOC(=O)c1nc(CN2CCN(c3ncccn3)CC2)cs1 +O=C(Cc1ccccn1)N1Cc2ccnn2CC(COCC2CC2)C1 +CC(COc1ccc(F)cc1F)NC(=O)NCCc1cccnc1 +COC(=O)CNC(=O)c1ncc(C)c2c(N)cccc12 +O=c1[nH]cc(Cl)cc1C1NCCc2cc(F)c(F)cc21 +CCC(C)Oc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(OC)cc2)c1C +O=C(c1ccco1)N1CCC(Oc2cccc(F)c2)CC1 +Cc1ccc(NC(=O)c2ccc3c(c2)CCC3)c(O)c1 +O=C(c1[nH]nc2c1CCCC2)N1CCN(CCO)CC1 +Cc1ccc(C(C)NS(=O)(=O)N2CCCCC2C)s1 +Nc1nc2n(n1)CCC(c1cc(Cl)cc(Cl)c1)C2 +CCc1noc(CC)c1CNC(=O)c1cccc(OC(F)F)c1 +CCc1sc(C(C)NC(=O)NCc2ncn(C)n2)cc1C +Cc1ccc(C(=O)NC(C#N)c2cccnc2)cc1 +COc1ncccc1C(=O)NCC(C)N(C)c1ccccc1 +COc1cccc(NC(=O)N2CC(c3nc(C)no3)C2)c1OC +COCCn1cc(C#N)c(=O)c2cc(Br)ccc21 +CCN(Cc1ccccc1C)C(=O)C1CCCN1C(=O)c1ccco1 +CC(=O)N(CCc1ccccc1)CC(=O)N(C)C(C)c1cccnc1 +NC(=O)COc1cccc(C(=O)NC2CCCC(C(F)(F)F)C2)c1 +CCc1noc(CC)c1CNC(=O)CCc1nc2c(F)cccc2[nH]1 +Cc1cn2c(CN(C)C(=O)c3scnc3C)c(C)nc2s1 +CC1CCCCN1C(=O)c1nc(-c2cnccn2)no1 +CC(C)CC(=O)Nc1ccc(C(N)=O)c(Cl)c1 +O=C(c1ccccn1)N1CCN(C(=O)C2CC2c2ccccc2)CC1 +Cc1ccc(C(C)C)cc1OCC(=O)NCC1CCCO1 +CCC(C)(C)NC(=O)C1CC(=O)N(Cc2ccccn2)C1 +CC(C)(C)OC(=O)N1CCCC1c1n[nH]c2ccccc12 +C#CCn1c(CCCCCNC(C)=O)nc2ccccc21 +Cc1ccc(C(=O)Nc2ccc3c(c2)nc(C(C)(C)C)n3C)cn1 +Cc1occc1CNC(=O)Nc1ccc(OCC2CCOCC2)cc1 +NC(=O)C1(NC(=O)CCCc2cn[nH]c2)CCCC1 +O=C(Nc1cc(C2CC2)n[nH]1)c1c(O)cc(F)cc1F +CNC(=O)C1CCCN(C(=O)NCc2ccnc(OC3CCC3)c2)C1 +Cc1ccccc1C(CC(=O)Nc1nc2c(s1)CCC2)NC(N)=O +Cc1cnc(CCNC(=O)N2C(C)CCCC2C)s1 +Cc1nc(CNC(=O)c2sc3ccccc3c2Cl)cs1 +CN(Cc1ccc(Br)cc1)C(=O)Cn1cnnn1 +CCn1nc(C)cc1C(=O)Nc1nnc(-c2cccs2)o1 +COC(=O)C(C)Oc1ccc(Br)cc1C(C)O +CC(C)Oc1ncc(C(=O)N2CCCC2Cn2cccn2)cc1Cl +CC(NC(N)=O)C(=O)N1CCN(c2ccccc2F)CC1 +CCS(=O)(=O)NCCc1cnn(-c2ccccc2)c1 +CC(C)c1ccc(C2CC(=O)Nc3n[nH]cc32)cc1 +CC(=O)N1CCN(c2nnc(SCC(=O)NC(C)C)s2)CC1 +Cc1cc(C(=O)NCCOc2nonc2C)c2ccc(C)c(C)c2n1 +CS(=O)(=O)NCCNC(=O)c1cccc(Br)c1 +Cn1ccc(Cn2c(S(C)(=O)=O)nc3ccccc32)cc1=O +Fc1ccc(Cc2noc(-c3ccc(-c4cn[nH]c4)nc3)n2)cc1 +NC(=O)c1coc(-c2csc(CC(F)(F)F)n2)c1 +COc1ccccc1N(CC(F)(F)F)C(=O)C1CCOC1C +CCC(=O)Nc1ccc2c(C(C)(C)C)cc(=O)[nH]c2c1 +CCNC(=O)NC(CC(=O)OC)c1ccccc1Cl +Cc1occc1C(=O)N1CCN(c2ncccn2)CC1 +CC(=O)N1CCc2[nH]nc(C(=O)N3CCN(C)CC3)c2C1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2cccc(CO)c2)c1 +O=C(NC1CC2C(=O)NCC(=O)N2C1)c1nc2ccccc2s1 +Cc1n[nH]c2ncc(C(=O)N3CCN(CC(C)O)CC3)cc12 +O=C(Nc1ccc(F)c(Cl)c1)N1CCC(O)C1 +Cc1nnc(NC(=O)c2cccn(Cc3ccccc3C)c2=O)s1 +O=C(NCc1ccccc1OC(F)F)C1CCCO1 +N#Cc1ccccc1NC(=O)COc1ccccc1Br +O=C(CC1CSc2nccc(=O)n21)Nc1ccccn1 +CCC(C)(C)NC(=O)c1ccc(=O)n(Cc2ccccc2)n1 +CCC(CC)NC(=O)c1ccccc1S(=O)(=O)C(C)C +CC(Sc1nncn1C)C(=O)Nc1ccccc1Br +CCc1nc(CCNC(=O)NC2CCCC2C)cs1 +Cc1nc(NCc2ccc3c(c2)CCO3)sc1-c1ccn(C)n1 +CC(C)(C)Oc1cc(CNC(=O)c2ccn3ccnc3c2)ccn1 +Cc1ccc(CC(=O)N2Cc3ccccc3CC2C(N)=O)cn1 +COC(=O)CN(C)Cc1cc2ccc(OC)cc2[nH]c1=O +Clc1cccc(Cl)c1CNCCc1nnc2n1CCCCC2 +Cc1cccc(NC(=O)C2CSc3ncc(C)c(=O)n3C2)c1 +Cc1nnc(NC(=O)c2cc(-c3ccncc3)nc3ccccc23)s1 +CC(C)COc1ccc(-c2cc(CO)c(=O)n(C)n2)cc1 +CC(C1CC1)N(C(=O)NCCCn1nc2ccccn2c1=O)C1CC1 +CC12CCC(=O)N1CCCN2Cc1cnn(-c2ccc(F)cc2)c1 +CCCCNC(=O)NC1CCN(C(=O)c2ccoc2)CC1 +CC(NC(=O)CN1CCOC2CCCCC21)C(=O)N(C)C +COCC(C)(CCO)NC(=O)c1ccc2cc[nH]c2c1 +COCC(=O)Nc1cccc(NC(=O)c2cn3c(C)cccc3n2)c1 +CCC(C)C(NC(=O)OC(C)(C)C)c1nnc(SC)o1 +CCn1ncc(C(=O)NCC2CCC(C)CC2)c1C(F)(F)F +Cn1ncnc1-c1ccnc(NCCc2nc(-c3cccnc3)no2)n1 +COC(=O)c1ccsc1NC(=O)COc1ccc(C)cc1 +COc1ccc(CNc2ccccc2C)cc1OC +CCn1cc(CNC(=O)c2sccc2Cl)cn1 +CCOc1ncccc1CNC(=O)N1CCNC(=O)C1 +Cn1c(SCC(=O)Nc2ccc(SC(F)F)cc2)n[nH]c1=O +O=S(=O)(Oc1ccc(-n2cnnn2)cc1)c1ccccc1Cl +O=C(CCOc1ccccc1F)Nc1ccccn1 +CC(NC(=O)C(NC(=O)c1ccc(C(C)(C)C)cc1)C(C)C)C(N)=O +CC(C)c1nc2cc(C(=O)NCCN3CCCCC3=O)ccc2o1 +CC(C)(C)C(=O)CNC(=O)COc1ccc(-n2cnnn2)cc1 +CCOc1ccc(NC(=O)NCCCC(N)=O)cc1Cl +Nc1c(-n2nnc3ccccc32)ncnc1-n1nnc2ccccc21 +CNC(=O)c1cc(C)ccc1NC(=O)COc1cccc(OC)c1 +CCN(CC)C(=O)c1cccc(NC(=O)N(C2CC2)C(C)C2CC2)c1 +Cc1ccnc(NC(=O)Cn2nnc3ccccc32)n1 +COc1ccc(OCC(=O)N2CCN(CCn3cccn3)CC2)cc1 +Cc1nn(CC(=O)Oc2cccc(N3CCCC3=O)c2)c(C)c1Cl +CCCn1nc(C(=O)NCC(=O)Nc2cccc(F)c2)ccc1=O +Cc1ccc(F)c(NC(=O)c2cc(N)cnc2C)c1 +CC(C)c1nnc2n1CCN(C(=O)COc1cccc(C(N)=O)c1)C2 +Cc1noc(C)c1CCCNC(=O)c1ccc(NC2CCC2)nc1 +Cc1ccc2[nH]c(=O)c(CNc3ccccc3C)cc2c1 +CCc1noc(CC)c1CNC(=O)CC1(N2CCOCC2)CCCC1 +COCCS(=O)(=O)NC(C)c1ccc(Br)cc1 +CNC(=O)NCCc1cc(Br)ccc1F +Cc1cc(C2CCCN2c2cc(C(F)(F)F)nc3ncnn23)no1 +Cc1noc(C(C)C)c1C(=O)Nc1nnc(C2CC2)s1 +Nc1ccc2c(Br)cnc(NCCO)c2c1 +Cc1cccc(CNC(=O)Cn2nc(C)c3c(C)onc3c2=O)c1 +CC(Oc1ccc(S(C)(=O)=O)cc1)C(=O)N(C)c1ccccc1 +COc1cccc(CNC(=O)NCC(O)c2ccc(Cl)cc2)c1 +COc1cccc(CS(=O)(=O)c2ccc(NC(C)=O)cc2)c1 +Cc1cccc(NC(=O)C(C)n2c(C)nc3onc(C)c3c2=O)c1C +CN(CCOCC1CC1)C(=O)C1CC1c1ccco1 +CCCOc1ccc(C(=O)N2CCN(Cc3ccccc3)CC2)cc1 +CCC(Oc1ccc(C)cc1)C(=O)NCc1ccco1 +O=C(NC(CC(F)(F)F)c1ccc(F)cc1)c1cnns1 +CC(NC(=O)NCC(O)c1cccc(F)c1)c1ccccc1 +CN(CCOc1cccc(Cl)c1)C(=O)CSc1nncs1 +Cc1nc(CNC(=O)CCn2c(=O)oc3ccccc32)c(C)s1 +COC(=O)CC(c1ccc(OC)c(C(C)(C)C)c1)C(C)C +Cc1cc(C)c(S(=O)(=O)N(CCO)CC(C)C)c(C)c1 +Cc1ccc(Cl)cc1Nc1nc(N)c(C#N)c(CC#N)c1C#N +c1ccc2sc(N3CCN(c4ccc5nncn5n4)CC3)nc2c1 +Cc1cnn(CC2CC2)c1NC(=O)c1oc2c(c1C)C(=O)CCC2 +CCN(CC)S(=O)(=O)c1ccc(C)c(C(=O)Nc2ccccn2)c1 +CC(=O)NCCCNC(=O)c1cc(C2CC2)nn1-c1ccccc1 +CCN1CC(C(=O)Nc2ccc(Cl)cc2C(N)=O)CC1=O +CCn1c(C)cc(O)c(C(=O)Nc2ccccc2)c1=O +CC(Sc1ccccn1)C(=O)Nc1cccc2cccnc12 +CCC(=O)N1CCc2cc(C(=O)Nc3ccc(C)cc3)ccc21 +COc1ccc(NC(=O)N2CCC3(CC2)OCCCO3)cc1 +CCc1nnc(SCC(=O)Nc2nncs2)n1N +COC(=O)C1(N(C)C(=O)c2ccc(F)cc2)CCCCC1 +C=CCn1c(NCC(=O)NCC)nc2sc3c(c2c1=O)CCCC3 +COC(=O)CCN(C)S(=O)(=O)CC1CCCO1 +COc1cccc(C(=O)Nc2ccc(C#N)cn2)c1 +NC(=O)C(OC(=O)Cc1c[nH]c2ccccc12)c1ccc(F)cc1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)c1cn2cccnc2n1 +CC(=O)n1nccc1-c1cc(-c2ccccc2)no1 +COC(=O)C1CCCN1C(=O)c1ccc2ccccc2c1 +Cc1cc(C)cc(OCC(=O)N2CCN(C)CC2)c1 +CCCCn1ncc(-c2ccc(OC)cc2)c(C(C)=O)c1=O +O=C(c1ccccn1)N1CCCC(COCc2ccccc2)C1 +COc1cccc(C(=O)NCCOc2ccc(S(C)(=O)=O)cc2)c1 +NS(=O)(=O)c1ccc(CCNCc2cccc(Cl)c2)cc1 +O=C(CC1CCC1)N=c1[nH]ccn1Cc1ccc(Br)cc1 +Cc1nc2n(n1)CC(Nc1ncnc3ccsc13)CC2 +O=C(NCC1CN2CCCCC2CO1)c1ccc(OCC2CC2)cc1 +CC(=O)c1cc(CCC(=O)N2CCCCC2C)oc1C +O=C(NCc1ccccc1OC1CCC1)NC1CC2CCC1O2 +O=C1CN(C(=O)CCCNC(=O)c2ccsc2)c2ccccc2N1 +CCOC(=O)C1CN(Cc2ccc(OC)cc2)CCC1=O +Cc1cc(CN2CCN(C(=O)NCCCn3cccn3)CC2)no1 +N#Cc1ccc(C(N)c2nnc(-c3cnccn3)o2)cc1 +CC(C)C(C)NC(=O)NCc1cc2ccccc2o1 +Cn1c(-c2cccs2)nn(CCNC(=O)C(C)(C)C)c1=O +COc1ccc(S(=O)(=O)n2nc(C)cc2C)c(C)c1C +CCNC(=O)c1ccc(NC(=O)N(C2CC2)C(C)C2CC2)cc1 +Cc1c(NCc2cc(Br)cs2)cccc1C(N)=O +Cc1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1 +Cc1ccc(NC(=O)NCC(C)(O)c2ccco2)cc1C +CCc1cccc(C)c1NC(=O)Cn1cc(Cl)c(=O)[nH]c1=O +COCCc1cc(NC(=O)c2cnn(-c3ccncc3)c2C)n(C)n1 +CCOc1cccc(C(=O)Nc2ccc(N)cc2OC)c1 +Cc1noc(C)c1C(=O)N1CCC2CCCCC2C1 +Cc1ccc(CN(C(=O)c2cc(-c3ccncc3)on2)C(C)C)s1 +NC(=O)N1CCCN(C(=O)Cc2coc3cc4c(cc23)CCC4)CC1 +NC(=O)c1cncc(C2OC(CO)C(O)C2O)c1 +COCCOc1ccccc1NC(=O)c1ccnc(-n2ccnc2)c1 +COc1cccc(OC2CN(C(=O)CCc3cccs3)C2)c1 +COCc1nc(C)cc(N2CCCC2c2nc3ccccc3[nH]2)n1 +COC(=O)c1cc(-c2csc(NC(=O)C3CC3C)n2)c[nH]1 +O=C(CC1OCCc2ccsc21)N1CCCC1Cn1cccn1 +COc1cccc(CN(C)CC2=NS(=O)(=O)c3ccccc3N2)c1 +CCc1cc(=O)[nH]c(-c2cccc(NC(=O)C3CC=CC3)c2)n1 +CCC(NC(=O)Nc1cc(C)nn1C)c1nc(C(F)(F)F)cs1 +CCc1nc(CCNC(=O)NCC(C)(C)c2ccncc2)cs1 +Cc1ccc(O)c(C(=O)N2CCCC(NC(=O)C(C)C)C2)c1 +Cc1cc(C(=O)NCc2ccccc2F)ccc1N +CN(Cc1ccccn1)C(=O)c1ccc(C2CCCCC2)cc1 +COCC(C)NC(=O)CNc1ccc(Br)cc1 +O=C(Nc1cccnc1-n1cncn1)c1ccc(Cl)c(Cl)c1 +Cc1nc(-c2ccco2)ccc1C(=O)N(C)c1ccc(C(N)=O)cc1 +C=CCSc1nnc(Cc2ccc(OC)cc2)o1 +CC(C)n1ncc2c1N=C(O)CC2c1cc(Cl)cc2c1OCOC2 +CC(C)N(CCC#N)C(=O)c1ccc(CNC(N)=O)cc1 +COc1cc(C2CC(=O)c3c(O)cc(O)cc3O2)cc(OC)c1OC +CC(CNc1cccc(C(N)=O)c1)c1ccccc1 +Cn1nc(C(=O)NCc2cccnc2)c2ccccc2c1=O +CCCc1nn2c(CO)c(-c3cccs3)nc2s1 +Cc1ccc(S(=O)(=O)CC(=O)N(C(C)C)C(C)C)cc1 +Cc1nnc(SCC(=O)N(C)Cc2ccccc2F)c(C#N)c1C +COc1ccc2ccn(CC(=O)Nc3cccc(C)c3C)c(=O)c2c1 +COCCNC(=O)NCC(C)(C)N1CC(C)OC(C)C1 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1c(C)cc(OC)cc1C +CCOc1ccc(C(=O)CNC(=O)c2ccccc2C)cc1 +c1coc(CNc2ncnc3oc(-c4ccco4)c(-c4ccco4)c23)c1 +COCCNC(=O)NCC(=O)Nc1ccc(Br)cc1C +CC(OC(=O)c1cnccn1)C(=O)Nc1cccc(C#N)c1 +COC(=O)c1cccc(C(=O)Nc2ccccn2)n1 +Cc1noc(C(C)NC(=O)Cc2nn(C)c(=O)c3ccccc23)n1 +COc1ccc(-c2cc(C(=O)OC(C)C)[nH]n2)c(OC)c1 +COc1cccc(OCCNC(=O)N2CCC(C)CC2)c1 +CC(C)(C)c1ncc2c(n1)CN(c1cc(N3CCOCC3)ncn1)C2 +O=C(Nc1ccncc1)C1CCCCN1C(=O)c1ccco1 +CCCc1n[nH]c(SCCCn2c(=O)[nH]c3ccccc32)n1 +Cn1cc(C(=O)C(C#N)c2nnc(-c3ccccc3)n2C)cn1 +CN(C)c1nc(NCCSc2nncn2C)ncc1F +COCC(NC(=O)NCC(C)(C)c1ccncc1)c1ccco1 +Cc1ccc(C#CCO)cc1NS(=O)(=O)N(C)C +Cc1cccn2c(CNc3nnc(C(F)(F)F)s3)cnc12 +COc1ccc(C(=O)NCCOc2cccnc2)cc1OC +C=CCNS(=O)(=O)Cc1ccc(NC(=O)c2ccoc2)cc1 +O=C(NC1CCN(c2ncccn2)CC1)N(CC1CCOC1)C1CC1 +C=C(C)Cn1c(=O)c2c(nc3n(CCC)c(C)c(C)n23)n(C)c1=O +Cc1noc(C)c1CC(=O)Nc1ccc(-n2ncc3ccccc32)cc1 +Cc1nc(C2CC2)ncc1C(=O)N1CCC(C)(O)C(O)C1 +Cc1nn(Cc2cccc(F)c2)c(=O)c2noc(C)c12 +CCN(CC)C(=O)CC1Sc2ncccc2N(CC(C)C)C1=O +CCn1nnc2c(SCC(=O)N3CCCCCC3)ncnc21 +C=CCOc1cccc(NCC(=O)N2CCOCC2)c1 +CC(C)(C)OC(=O)N1CCc2c([nH]c3cc(C(C)(C)C)nn3c2=O)C1 +COc1ccc(-c2nsc(NC(=O)C(C)C)n2)cc1OC +CCOCC1CCCC12CN(Cc1ccc(C)o1)CCO2 +O=C(COc1cc(=O)n2ccccc2n1)Nc1cccc(Cl)c1 +CCOc1cc(C(=O)NCCC(=O)N2CCCCC2)ccc1OC +NC(=O)NCCC(=O)Nc1c[nH]cc(Br)c1=O +O=C(NCc1ccoc1)Nc1nnc(C2CC2)s1 +CCc1cc(C(=O)NCCc2cnn(-c3ccccc3)c2)[nH]n1 +CCC(=O)Nc1ccc(C)c(NCC(=O)N2C(C)CCCC2C)c1 +O=C(NCC1CC1)Nc1cccc(C(F)(F)F)c1 +COc1ccc2cc(NC(=O)c3cccs3)cnc2c1 +COCc1nc2c(NC(=O)CCc3c(C)noc3C)cccn2n1 +CC(NC(=O)Cn1cnc2cc(F)ccc2c1=O)C(=O)N(C)C +COc1ccc2nc(C(=O)NC(C)(C)C)sc2c1 +Cc1ccc(C(C)NC(=O)Cn2c(C)csc2=O)o1 +COC(=O)N1CCC(NC(=O)c2cc(F)c(F)cc2Cl)CC1 +O=c1cc(CO)occ1OCCCOc1ccc(Cl)cc1 +CCc1cc(OCC(=O)N(C)C2CC2)ccc1Cl +O=C(NCc1nncn1C1CC1)Nc1ccc(C(=O)NC2CC2)cc1 +CC(NC(=O)CCSc1nnc(C(C)(C)C)n1N)c1ccccc1 +CN(CC1CCCCC1)C(=O)CNC(=O)c1ccsc1 +Cc1n[nH]c(C)c1CNc1ncnc2ccsc12 +O=C(c1ccnc(OC2CCC2)c1)N1CCOC(C2CCCO2)C1 +COCCN(C)C(=O)Nc1cc(Br)ccc1C +CC(CC#N)N(C)C(=O)Nc1cccc(S(C)=O)c1 +Cc1noc(NC(=O)c2sc(Cc3ccccc3)nc2C)n1 +Cc1nc(SCC(=O)N2CCC(C)CC2)c2c(C)c(C)sc2n1 +COc1cccc(C(N)=O)c1OCC(=O)N(c1ccccc1)C(C)C +COC(=O)Cn1nc(-c2ccc3c(c2)OCCCO3)ccc1=O +O=c1cc(C2NCCc3cc(Cl)cc(Cl)c32)cc[nH]1 +Cc1cccc(OC(C)C(=O)NCCNC(=O)c2ccc(F)cc2)c1 +COc1ccccc1C1CCCN1S(=O)(=O)c1c(C)n[nH]c1C +CNc1nc2ccccn2c1S(=O)(=O)N(C)C +COC(=O)Cn1c(=O)cc(C(F)F)c2c(C)nn(-c3ccccc3)c21 +O=C(Nc1cccc(-c2nnnn2C2CC2)c1)c1cc2ccccc2o1 +O=c1[nH]c(CN2CCc3ccccc32)nc2cc(Cl)ccc12 +CC(C)N(C(=O)CNc1ccc(F)c(C#N)c1)c1ccccc1 +CCOc1cccc(-c2noc(C)c2C(=O)OC)c1 +Cc1ccccc1C1CC1C(=O)N1CCN(C(=O)CCC(C)C)CC1 +COC(=O)CNC(=O)CN(c1ccc(Cl)cc1)S(C)(=O)=O +CSc1cc(C(=O)NCCCC(N)=O)ccn1 +Cc1cc(NC(=O)CCc2ccsc2)n(Cc2ccccc2)n1 +CC(=O)N1c2ccccc2CC1c1nc(C2CC2)no1 +CCOc1ccccc1C(=O)N1CCC(Oc2ccc(C)nn2)CC1 +CC(C)(CNC(=O)c1csc(-c2ncccn2)n1)N1CCOCC1 +CC(C)Oc1ccccc1CC(=O)Nc1ccc2c(c1)COC2 +O=C(Cc1ccc(F)cc1)NC1CC(=O)N(C2CC2)C1 +CNC(=O)c1ccsc1NC(=O)c1ccc(F)cc1 +O=C(Cc1csc(-c2ccccc2)n1)Nc1nncs1 +Cc1cc(NC(=O)C(C)n2cc(Br)c(C)n2)no1 +COc1nn(C)cc1C(=O)Nc1ccc(N2CCCC2=O)c(C)c1 +CC(NC(=O)c1ccoc1)C(=O)Oc1ccc(F)cc1 +COc1ccc(C(C)NC(=O)c2n[nH]c3ccccc23)cc1F +Cc1ccc(Cl)cc1NCC(=O)N(C)C(C)C +COc1ccc(Cl)cc1N(C)C(=O)c1cccc(C#N)c1 +Cc1cnc(-c2nc(-c3cccc(NC(=O)C4CC4)c3)no2)cn1 +C#Cc1cccc(N(Cc2cccs2)C(=O)c2ccc(OC)nn2)c1 +Cc1ccc(Cl)cc1NC(=O)C1(C#N)CCCC1 +COCCOC(=O)C1=C(C)Nc2ncnn2C1c1ccccc1 +CC(Cc1ccc(Cl)cc1)NC(=O)CNC(=O)c1ccsc1 +Cc1csc(SCC(=O)Nc2cc(C)nc3ccccc23)n1 +CCOc1ccc(C(=O)CSc2nnnn2-c2ccccc2)cc1 +CN1CCN(C(=O)NCCCn2cncn2)C(c2ccccc2)C1 +O=C(NCCOCC(F)(F)F)c1ccc(-c2ccco2)[nH]c1=O +Cc1cccc(NC(=O)N(C)CCc2c(C)nn(C)c2C)c1C +CCc1ccc(N2C(=O)c3ccccc3NC2(C)C)cc1 +CC(C)(C)NC(=O)c1cc(Cl)c2c(c1)OCCO2 +Cc1ccc(C(=O)NC(C)c2sc(C)nc2C)s1 +Cc1cc(F)ccc1S(=O)(=O)N(CCO)CCO +Cc1cccc(OCC(=O)Nc2c(C)nc3sccn3c2=O)c1C +COCc1noc(CNCc2cc(=O)c3cccc(F)c3[nH]2)n1 +CCc1nnc(NC(=O)c2nc(C)sc2-c2ccccc2)s1 +CCC(CC)C(=O)Nc1ccc(OC)cc1OC +Cc1occc1C(=O)Nc1ccc2[nH]c3ccccc3c2c1 +CCc1nc(CN2CCCC(CN3CCOCC3)C2)cs1 +Cc1cc(C)c2c(c1)NC(=O)C2Cc1nc(Cc2ccccc2)n[nH]1 +Cc1occc1COC(=O)C1CCCN(C(N)=O)C1 +COC(=O)C(NCc1cccc(OC)n1)C(C)(C)C +COc1ccc(C(=O)NCc2ccc(OC(C)C)cc2)cc1F +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(F)cc1F +O=C(Cc1cccs1)NCCn1ccnc1-c1ncccn1 +O=C(COc1ccccc1Cc1ccccc1)NCc1ccccn1 +CC(NC(=O)c1cccc(S(=O)(=O)NC2CC2)c1)C1CCCO1 +Cc1c(Br)cc2c(c1C)NC(=O)C2=O +Cc1cc(C(=O)N2CCc3ncnc(C4CC4)c3CC2)c(C)o1 +O=C(NCCO)c1cc(C(=O)c2ccc(Cl)cc2Cl)c[nH]1 +CCC(CC(=O)OC)c1ccc(OC)c(C(C)(C)C)c1 +COCCCNC(=O)c1ccn2c(-c3ccccc3Cl)nnc2c1 +CCC(C)NC(=O)CCNC(=O)NC(C)c1ccccn1 +CC(=O)NCCCNC(=O)NC(C)c1ccc2c(c1)OCCCO2 +CCCC(C)NC(=O)C(C)Sc1nnc(N2CCOCC2)n1C +CC(C)C(=O)NC1CCCN(C(=O)c2ccc(C(=O)N(C)C)cc2)C1 +CCCCC(=O)Nc1ccc(C(=O)NCc2ccncc2)cc1 +CC(=O)N1CCC(C(=O)N2CCN(C)CC2)CC1 +CCNC(=O)c1cc(-c2ccccc2OCCC(C)C)nc(N)n1 +CCn1ccc2ccc(NC(=O)NCc3cccnc3OC)cc21 +Cc1[nH]ncc1CCCNC(=O)NCc1ccncc1 +O=C1CN(c2ccc(NC(=O)CCc3ccncc3)cn2)CCN1 +CCCNC(=O)Nc1ccc(C)c(NC(=O)NCCC)c1 +COc1cccc(C(=O)NC(C)c2ccc3c(c2)OCO3)c1OC +Cc1cccc(N2CCN(CCC(=O)c3ccccc3N)CC2)c1 +Cc1cc(Cl)ccc1OCCCNC(=O)c1ccc[nH]1 +COC(=O)C(C#N)c1ncc(Br)cn1 +N#Cc1ccc(C(C#N)CC(=O)N2CCCC2)cc1 +O=C(NCc1cccnc1)C1CCN(C(=O)Nc2cccs2)CC1 +CC(c1ccccc1F)N(C)C(=O)NCC(=O)NC(C)(C)C +Cn1cc(NC(=O)N2CCN(C(=O)CCC3CCCCC3)CC2)cn1 +CC1CN(C(=O)Nc2cccc(COCc3ccco3)c2)CCO1 +Nc1cnc2nc(-c3ccc(C(F)(F)F)cc3)[nH]c2c1 +CN(C(=O)c1ccc(OCC(F)F)nc1)c1ccccn1 +O=S(=O)(Nc1ccc2ccccc2c1)c1cn[nH]c1 +Cc1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1 +CCc1onc(C)c1NC(=O)NCc1nncn1-c1ccccc1 +Cc1ccc(CNC(=O)Cc2n[nH]c(=O)c3ccccc23)cc1 +CCCOc1cccc(NC(=O)N(C)Cc2ccncc2)c1 +CC1CCCN(C(=O)C(NC(=O)c2c(F)cccc2F)C(C)C)C1 +COc1ccc(S(=O)(=O)N2CCCC(C)C2)cc1OC +c1ccc(-c2ccnc3nc(C4CCC4)nn23)nc1 +O=C(CCn1ccnc1-c1cnccn1)Nc1ccccc1 +COc1cc2c(cc1O)CCNC2c1ccccn1 +CC(C)(C)CCNC(=O)CSc1n[nH]c(N)n1 +CCc1nc(CNC(=O)NCc2sccc2C)cs1 +COC(=O)c1cccc(-c2noc(CCc3nc(C)no3)n2)c1 +CC1CC1C(=O)NCCC(=O)Nc1cccc2cn[nH]c12 +O=C(Nc1c[nH]c(=O)[nH]c1=O)NC12CC3CC(CC(C3)C1)C2 +CC(=O)N1CC2CCC(C1)N(C(=O)c1c(F)ccc(C)c1Cl)C2 +COc1ccc(N(Cc2cccs2)C(=O)c2cnn(C)c2C)cc1 +COc1cccc(NC(=O)c2cccnc2SC)c1 +O=C(CCN1C(=O)COc2ccccc21)OC1CCCCCC1 +CCC(Cn1nnc2ccccc2c1=O)NC(=O)C1CCC1 +CCOc1ccccc1C(=O)Nc1ccc(CC(=O)NC)cc1 +Cc1nnc(COc2ccc(NC(=O)c3ncoc3C(C)C)cc2)o1 +CCOC(=O)CCC(C)NC(=O)c1n[nH]c(=O)c2ccccc12 +NC(=O)c1cccc(NC(=O)CCc2c[nH]c3ccccc23)c1 +Cn1ccsc1=NC(=O)C1(c2ccccc2)CC1 +Cc1cc(C)c(C(=O)NCC(C)(C)N2CC(C)OC(C)C2)c(=O)[nH]1 +COC(=O)c1sccc1CN1CC(C)C(=O)Nc2ccccc21 +COC(=O)c1sc2ncn(Cc3ccccc3C)c(=O)c2c1C +COC(=O)C1c2ccsc2CCN1C(=O)c1ccc(Cl)cc1 +CC(=O)c1cnn(-c2cc(Oc3cc(C)cc(C)c3)nc(C)n2)c1C +Cc1cc(CC#N)nn1-c1cccc(C(F)(F)F)c1 +CC(C)(CNC(=O)COc1ccc2c(c1)CCC2)c1ccncc1 +O=C(c1cccc(F)c1)N(CC(F)(F)F)C1CCOCC1 +Cc1c(C)c(C)c(C(=O)OCc2nnc(C3CC3)o2)c(C)c1C +Cn1nc(C(=O)OC(c2ccccc2)c2nccs2)ccc1=O +O=C(CN1C(=O)c2cccc3cccc1c23)NCC(F)(F)F +CCN(CC(F)(F)F)C(=O)c1cc(N)c(C)s1 +O=C1CCC(C2NCCc3ccc4cc(O)ccc4c32)N1 +Cc1nc2cc(NC(=O)c3cnn(-c4ccncc4)c3C)ccc2o1 +CC(C)c1ccc2occ(CC(=O)N3CCN(C)CC3)c2c1 +Cc1cc(C)c(NC(=O)Cn2cccc(C)c2=O)c(Cl)c1 +N#CCn1cnc2cc(-c3ccc(Cl)cc3)sc2c1=O +CC1CN(C(=O)c2cnc3c(cnn3Cc3ccccc3)c2)CCO1 +CCN(CC(=O)N1CCNCC1)S(=O)(=O)c1ccc(C)cc1C +COC(=O)c1cccc(C(=O)NC(C(N)=O)C(C)C)c1 +Cc1cc(Cl)ccc1NC(=O)c1cccc(NC(N)=O)c1 +CC(C)OCCCNC(=O)c1cn(-c2cccc(Cl)c2)nn1 +CC(C)Nc1ccc(N2Cc3ncccc3C2=O)cn1 +c1cnc(-c2nnc(-c3cnc4onc(C5CC5)c4c3)o2)cn1 +Cc1nc(CNC(=O)NCCC(C)(C)C)cs1 +CNC(=O)c1ccc(NC(=O)C(C)Oc2ccc(Cl)cc2)cc1 +Cc1nn(-c2ccc(F)cc2)c(C)c1CC(=O)NCC(C)O +Cc1ccc(-n2c(SCCC#N)nnc2N2CCCC2)cc1 +CCCCn1cc(C(=O)NCCC)c(=O)c2c(N)cccc21 +CCC(CO)NC(=O)c1cn(C)nc1C(C)(C)C +O=C(CSc1ccccn1)N1CCN(c2ccc(F)cc2)CC1 +CC(C)C(NC(=O)NCC1CCC1)c1cccs1 +Cc1n[nH]c(SCCC(=O)Nc2cccc(Cl)c2N(C)C)n1 +CC1CC(C)(C)N(C(=O)Cn2ccnn2)c2ccccc21 +Cc1nnc(NC(=O)NCc2ccc(OC3CCCC3)nc2)s1 +O=c1cc(C(F)(F)F)nc2nc3c(nnc4ccccc43)nn12 +Cc1ccc(-n2nnnc2SCC(=O)NC(C)(C)C)cc1C +Nc1ccccc1CC(=O)Nc1ccc(F)c(Cl)c1 +O=C(c1cc(Br)cc2c1OCC2)N1CCOCC1 +CC(=O)NCC(=O)NCC(=O)NC(C)c1cccs1 +Cc1ccc(OCC#CCNC(=O)c2csc(C)n2)cn1 +O=C(CC1CCCCC1)Nc1ncn(Cc2cccnc2)n1 +CC(C)OC(=O)CN1CC(C(C)C)Oc2cccc(N)c21 +CCCCN(C(=O)c1cncc(Br)c1)C(C)CC +C=CCN(C(=O)c1ccc2c(c1)CCCN2)C(C)C +O=C(Nc1ccc2oc(=O)[nH]c2c1)C1(c2cccc(F)c2)CCC1 +CCCOCCOC(=O)c1cncc(Br)c1 +Cc1ccc(NS(=O)(=O)c2ccc(-c3ccc(=O)[nH]n3)o2)cc1 +COc1cccc(C(=O)Nc2ccc(C(C)=O)cc2)c1OC +CCCNC(=O)c1cc(-c2csc(CC)n2)n2ccccc12 +CC(=O)N(C)c1ccc(NC(=O)OCC(F)(F)F)cc1 +CC(=O)c1ccc(NC(=O)C2CCN(C(C)=O)CC2)cc1C +COCCn1cc(C(=O)NCCc2ccccc2)ccc1=O +CN(CCC#N)S(=O)(=O)N1CCOC(c2ccc(Cl)cc2)C1 +CCCc1c(C#N)nnn1-c1ccc(OC)cc1OC +O=C(CNC(=O)c1ccccc1)NCCCN1CCCCCC1=O +Cc1[nH]c(=O)n(C)c(=O)c1S(=O)(=O)N(C)Cc1ccccc1 +COC(=O)CSc1ccc(NC(=O)c2ccccc2F)nn1 +Cn1nc(C(C)(C)C)cc1C(=O)NCCc1ccc2c(c1)OCO2 +Cn1cc(S(=O)(=O)NCCCOc2cccc3cccnc23)cn1 +COc1ncccc1CNC(=O)Nc1cccc(-c2nccs2)c1 +COc1nc(NCc2scnc2C)ccc1N +O=C(CNc1cc(F)ccc1Cl)NCc1ccc2c(c1)OCO2 +Cc1nc(CNc2cc(Br)c(F)cc2Cl)no1 +COc1ccnc(N2CCN(C(=O)C3(c4ccccc4)CC3)CC2)n1 +CCOC(=O)c1nn(CCCc2ccccc2)c(N)c1C#N +CN(CC(=O)OC(C)(C)C)C(=O)c1cc(F)c(Cl)cc1Cl +CNC(=O)CC1CC2(CCCC2)Oc2ccccc21 +CC(C1CC1)N(C)c1ccc(S(N)(=O)=O)cc1N +Cc1cc(C)cc(NC(=O)N(C)Cc2nccn2C(F)F)c1 +CN(C(C#N)c1ccccn1)S(=O)(=O)c1cccs1 +Cn1c(=O)ccn(CC(=O)Nc2ccc3c(c2)COC3)c1=O +COc1c(Cl)c(OC)c2c(c1OC)CNCC21CC1 +Cc1nnnn1-c1cccc(NC(=O)NC2CCCCCC2CO)c1 +Cc1nc(NCc2ccco2)c(C#N)c2c1CCCC2 +COC(=O)NC1(C(=O)Nc2nc(-c3ccccn3)cs2)CCCC1 +COCc1ccc(C(=O)NCc2ccc(C)cc2C)o1 +COc1ccc(CC(=O)NCC(O)c2cccs2)cc1 +CC(=O)Nc1nc(C(=O)N(C)c2nc3ccccc3s2)cs1 +CCOc1ccc(NC(=O)CNC(=O)C2CCCCC2)cc1OC +CCN(CC)C(=O)N1CCC(C(=O)Oc2cccc(F)c2)CC1 +CCCN(CC1CC1)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +CCCC(C)C(=O)NCCC(=O)N1CCN(c2ncccn2)CC1 +OCCCN(Cc1nc(-c2cccnc2)no1)c1ccccc1 +Cc1cc(=O)[nH]cc1C(=O)N1Cc2ccccc2N(C)CC1C +COc1cc2ncnc(NCc3cccc(F)c3)c2cc1OC +O=C(CNC(=O)NCC1(N2CCOCC2)CCCCC1)NC1CC1 +Oc1ccc(CNc2ccccc2F)c(Cl)c1 +Cc1noc(C)c1CC(=O)N(CCC#N)CCC(F)(F)F +Cc1ccn(CCC(=O)N2CCCCC2c2cc[nH]n2)n1 +Nc1ccc(NC(=O)Nc2cccc(Cl)c2)cc1F +Cc1ccc2nc(C(=O)NCc3nccn3Cc3ccccc3)cn2c1 +COC(=O)C1CCCN(C(=O)C(CC(C)C)N2CCCCC2=O)C1 +CC(Cc1ccco1)NC(=O)CCc1ccsc1 +C#CCNC(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2C)CC1 +COc1cc(NC(=O)C(C)Oc2ccc(C#N)cc2)cc(OC)c1 +Cc1ccc(Cn2ncc3c(NCc4cccnc4)ncnc32)cc1 +CC(C)C(NC(=O)c1ccc(Cl)cc1)C(=O)Nc1nccs1 +COc1ccc(CCNC(=O)NCc2cc(C)on2)cc1 +O=C(Nc1cc(C(F)(F)F)ccc1-n1cccn1)c1cccnc1 +COc1ccccc1-c1csc(CC(=O)NCc2ccccc2)n1 +O=C(c1cc(Br)ccc1-n1cnnn1)N1CCCC1 +O=C1C2CN(c3ncccn3)CC2CN1CC1CC1 +CCc1cc2c(=O)[nH]c(-c3cccc(O)c3)nc2s1 +CC(C)c1ncc(CN2CCC(Oc3ccccc3)CC2)s1 +Cc1ccc(OCCCC(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +CC(NC(=O)c1cc(C(=O)NC(C)C(C)(C)C)n(C)n1)C(C)(C)C +Nc1ccc(NS(=O)(=O)c2cn[nH]c2)c(Br)c1 +COc1ccc(OC(=O)C(C)NC(=O)c2ccco2)cc1 +CC1CCCC(CNC(=O)Nc2nnc(C(F)(F)F)s2)C1 +CCCC(=O)Nc1cnn(CC(=O)Nc2ccc(SC)cc2)c1 +COc1ccc(CNC(=O)N2CCN(CC(F)F)CC2)cc1 +CC(=O)Nc1ccc2c(c1)nc(C)n2Cc1ccccc1 +Cc1cc(C)c(NC(=O)CSc2ncnc3[nH]cnc23)c(C)c1 +CCCC(C)C(=O)Oc1cccc(NC(=O)C2CC2)c1 +CC1CN(Cc2ccccc2)CCN1C(=O)Cc1ccc[nH]1 +O=C(NCc1nc2ccccc2s1)N1CCc2ccccc2C1 +CS(=O)(=O)N1CCCC1C(=O)NCc1ccc(Cl)cc1 +O=C(COC(=O)c1cc(F)ccc1F)Nc1cccc(Cl)c1 +CC(=O)Nc1cc(C(=O)NCCC(=O)NC2CCCCC2)ccc1F +CC(c1nc2ccccc2c(=O)[nH]1)N(C)CCOc1ccccc1F +CC(C)NC(=O)CCNc1cnn(-c2ccccc2)c(=O)c1Cl +CCC(C)NC(=O)CCCNC(=O)c1ccco1 +CCCOc1cccc(NC(=O)c2cn(CC(=O)N(C)C)nn2)c1 +CCOCC(=O)N1CCc2c(nc(-c3ccccc3)nc2N(C)C)C1 +COc1cccc(C(=O)N2CCCCCC2c2ccco2)c1F +COc1ccc(C)cc1C(=O)CCCC(=O)NC1CC1 +O=C(Nc1ccc2c(c1)CCC2)NC1c2ccccc2CC1O +CCc1nc2ccc(-c3noc(-c4ccco4)n3)cc2n1CC +Cn1nc(C2CC2)cc1C(=O)Nc1cc(-c2ccncc2)n[nH]1 +Cc1nc(CN(C)C(=O)NCc2cc3ccccc3[nH]2)cs1 +Cc1ccc(CCNC(=O)c2cc3c(C)nccc3[nH]c2=O)cc1 +CC(C)NC(=O)c1cc(O)c2cc(Cl)ccc2c1 +N#CCc1cnc(CCOc2cccc(Cl)c2)s1 +Cc1n[nH]cc1CNC(=O)CCOc1ccc(Br)cc1 +COC(=O)CN(C(=O)CCc1c(C)nn(C)c1C)C(C)C +COc1cc(C)sc1C(=O)NCCOc1cccc(NC(C)=O)c1 +COC(=O)CCCN1CCc2ccc(Cl)cc2C1 +CCc1ccccc1NC(=O)Nc1ccc2nnc(C)n2c1 +CNC(=O)Cc1csc(NC(=O)c2ccc(=O)[nH]c2)n1 +CC(=O)Nc1cc(NC(=O)C(C)(C)C)ccc1F +Cc1onc(-c2ccccc2)c1C(=O)Nc1ccc2ccccc2n1 +Cc1ccc(OCCN(C)C(=O)c2ccc(C#N)cc2)cc1 +CC(O)CNC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +Cc1ncc(CNC(=O)c2ccc(Cl)cc2N2CCCC2=O)s1 +O=C(NC1CCCNC1=O)C1CC(=O)N(c2ccc3c(c2)CCC3)C1 +CC(=O)NC(C(=O)Nc1nnc(C2CC2)s1)C1CCCC1 +Nc1nccnc1C(=O)Nc1ccc(N2CCCC2)nc1 +CC1(NC(=O)CCCNC(=O)c2cccs2)Cc2ccccc2C1 +CC(O)CNc1ncc(Br)c2ccccc12 +CNC(=O)CCNC(=O)C(C)Sc1nncs1 +Cc1cc(C(=O)NCC(=O)Nc2ccc3ccccc3c2)n(C)n1 +O=C(c1ccc(Br)cc1)C1CCCO1 +CCCCn1nc(C(=O)Nc2c(C)cccc2C)ccc1=O +Cc1ccccc1C(=O)NC(C)c1c(C)noc1C +Cc1ccc(C)c(OC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 +COc1ccc(NC(=O)c2cc(C)on2)c(OC)c1 +C#CCN(c1ccc2nnnn2n1)C1CCCCC1 +CCCc1nc(NCc2ccccc2F)c(N)c(OC)n1 +CCC(NC(=O)CNC(=O)C(C)(C)C)c1ccccc1OC +CC(C)c1ccc(CCC(=O)NC2CCN(C(N)=O)CC2)cc1 +Cc1cccc(C(=O)N2CCC(c3nc4ccccc4o3)CC2)c1 +CCCc1ccc(C(O)CNC(=O)c2ccc(OC)cc2)cc1 +COc1ccc(F)cc1C(=O)COc1ccc(-c2nnco2)cc1 +Cc1cc(C(=O)Nc2nc3c(F)cc(F)cc3s2)on1 +COCCN(Cc1ccc(Cl)c(F)c1)CC(F)(F)F +CCOC(C)C(=O)N(C)Cc1cc(Cl)cc(Cl)c1 +Cc1n[nH]c(C(=O)N(C)C2CCCCCC2)c1Br +CC(CNC(=O)c1cc(-c2ccccc2)no1)N1CCOCC1 +CCn1nnc2c(Nc3ccc(OC(F)F)cc3)ncnc21 +CCCC(=O)N1CC(OCc2ccc(F)cc2Cl)C1 +CC1=NC2(CCC3CN(c4ccncn4)CC32)C(=O)N1CC1CC1 +O=C(COc1ccc(F)cc1)Nc1onc2c1CCCC2 +N#Cc1c(N)n(CCO)c2nc3ccccc3nc12 +NC(=O)CCc1ncc(C(F)(F)F)cc1Cl +NC(=O)c1cnc(NC(=O)c2csc(-c3ccc(F)cc3)n2)s1 +Cc1ccn2c(=NC(=O)C3CCCCC3)[nH]nc2c1 +Cc1cccc(OCC(O)Cn2cnc3ccc(Cl)cc3c2=O)c1 +COCC(C)N1CCN(C(=O)CNC(=O)c2ccccc2)CC1 +Brc1c(-c2cc[nH]n2)nn2cccnc12 +CC(=O)n1c(SCC(=O)Nc2nccs2)nc2ccccc21 +CNc1ncc(C(=O)N2CCCC(CO)(CC=C(C)C)C2)cn1 +O=C(c1cccc2[nH]ncc12)N(Cc1cccnc1)CC1CCCO1 +COc1ccc(Br)cc1NCCc1ccccn1 +CNC(=O)c1cc(S(=O)(=O)N2CCCCC2)cn1C +CC(NC(=O)c1ccc2ccccc2n1)c1ccc(NC(N)=O)cc1 +Cn1cc(C(=O)NCc2ccccc2F)c(C(C)(C)C)n1 +CCOC(=O)N1CCC(c2nnc(C(C)C)o2)CC1 +O=C(NC1CCc2cc(F)ccc21)N1CCN(c2ncccn2)CC1 +COc1ccc(-c2nc(Cn3cccn3)c(C)o2)c(F)c1 +CC(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +COC(=O)c1cccc2c1CCCN2C(=O)CCc1ccco1 +C=CCNC(=O)Nc1ccc(OCC(=O)N(C)C)cc1 +CN(C(=O)c1ccc(F)cc1)c1nc2ccccc2o1 +O=C(CCCc1cc(F)ccc1F)NCC1CCCC(O)C1 +CCCOc1cccc(C(=O)N2CCNC(=O)CC2)c1 +CCN1CCN(S(=O)(=O)c2ccc(C(=O)OC)cc2Cl)CC1 +CCC(C)c1ccc(C(=O)CN2CCN(C(C)=O)CC2)cc1 +COc1cccc(NC(=O)c2c[nH]c3cccc(F)c23)c1 +Cc1ccc(-c2cc(CC#N)c(=O)n(CC(C)C)n2)cc1 +CN(C)S(=O)(=O)c1ccc(C(=O)OCC(=O)NC2CC2)cc1 +CN(C(=O)CCNC(=O)C(O)c1ccccc1)c1ccccc1 +O=C(NCc1cc(-c2ccco2)on1)c1ccc(C(F)(F)F)cc1 +CC(C)N(Cc1nccn1C)C(=O)c1ccc2nc(C3CC3)oc2c1 +C=CCC(NC(C)=O)C(=O)N1CCCC1Cn1cccn1 +CCCCN(C)C(=O)Cn1c(CC)nc2c(N)cccc21 +CCC(=O)c1ccc(OC(=O)Cn2cnc3ccccc3c2=O)cc1 +NC(=O)c1cccc(NC(=O)CCc2ccco2)c1 +Nc1ccc(F)cc1CS(=O)(=O)c1ccccc1Br +C#CCNC(=O)c1ccccc1NCC(=O)N1CCNC(=O)C1 +CCOc1ccc(C(=O)Nc2ccc3c(C)cc(=O)[nH]c3c2)cc1 +COc1cc(C(=O)n2ncc(C#N)c2N)ccc1OC1CCCC1 +N#Cc1ccc(OCCSc2nnc3n2CCCCC3)cc1 +COc1ccc(CCNC(=O)c2cnn3cc(C)cnc23)cc1C +CCC(=O)N1CCCC1C(=O)c1ccc(OC)c(OC)c1 +COCCN1C(C)CN(Cc2cnc(C3CCC3)s2)CC1C +O=C(c1ccc2ccccc2c1)N1CCC2(CC1)OCCO2 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(C)cc2Cl)cc1 +CC1CC1C(=O)NCc1csc(-c2ccccc2)n1 +COc1ccc(Br)c(C(=O)NC2CCCNC2=O)c1 +Cc1cc(CN2CCN(c3ccc4nncn4n3)CC2)no1 +CCOC(=O)c1nc2sc(C)c(-c3cccs3)n2c1N +CCS(=O)(=O)NCC(=O)Nc1ccc(F)c(F)c1F +CC(=O)NCCNC(=O)NC1CCc2ccccc21 +NC(=O)c1ccc(C(=O)Nc2ccc(N3CCCCC3)cn2)cc1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)NC(C)(C)C)cc1 +N#Cc1cccc(NCC(=O)c2ccc3c(c2)OCCO3)c1 +O=S(=O)(Nc1ccc(F)cc1F)c1ccc(F)cc1 +CC(CCc1cccc(F)c1)C(=O)N1CCC(O)C1 +CCN(C(=O)c1ccccc1OCCOC)c1cccnc1 +O=C(CO)N1CCN(C(=O)CCc2nc(-c3ccco3)no2)CC1 +CS(=O)(=O)NCCNC(=O)c1c(Cl)ccc(Cl)c1Cl +C=C(C)COC(=O)c1c(-c2ccccc2)noc1C +Cc1nc2ccccc2nc1CN(C)CC(=O)N1CCCC1 +CCOC(=O)c1ccccc1Nc1cc(N)nc(C2CC2)n1 +CC(C)COCCNS(=O)(=O)c1ccc2oc(=O)ccc2c1 +CCCNC(=O)Cn1nnc(CO)c1C(F)(F)F +CCn1ccc(C(=O)Nc2sc3c(c2C(=O)OC)CCC3)n1 +COc1cc(CNc2ccccc2C(F)(F)F)ccc1O +O=C(NCCN1CCOCC1)Nc1cccc(Cl)c1Cl +Cc1nn2c(-c3cc(N)ccc3Cl)nnc2s1 +Cc1ncc(C(C)NCc2ccccc2Cl)s1 +COc1ccc(CCCC(=O)NC2CCCC2C(N)=O)cc1F +CN(Cc1ccccc1)C(=O)CS(=O)(=O)c1ccccc1 +CNc1ccc(C2CN(C(=O)c3ccccc3)CCO2)nc1 +NC(=O)Cc1csc(NC(=O)CC2C=CCC2)n1 +COc1cc(C#N)ccc1OC(C)C(=O)c1ccc2c(c1)CCC2 +Cc1cccc(C)c1OC(=O)CCOCC1CCCO1 +COc1ccc(CCC(=O)N2CC(C)OC(C)C2)cc1N +Cc1ccc(NC(=O)COC(=O)c2ccc[nH]2)c(Cl)c1 +CCOc1ccc(OC(=O)Cc2c(C)noc2C)cc1 +CCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)[nH]c(=O)n2C +CN(C)C(=O)CN(C)C(=O)COc1ccc2ccccc2c1 +NC(=O)c1cccc(Oc2c(F)cc(N)cc2F)c1 +Cc1ccc2cc(C(=O)N3CCN(C(=O)N(C)C)CC3)ccc2n1 +CCNC(=O)N1CC2OCC(=O)N(Cc3ccc(F)cc3)C2C1 +CCn1cc2c(n1)C(COCC1CC1)CN(Cc1ccc(F)cc1)C2 +Cn1c2ccc(F)cc2c2nc3n(c(=O)c21)CCS3 +CC1C=C(c2csc(-c3ccccc3)n2)C(C)N1c1ncn[nH]1 +COc1cccc(S(=O)(=O)C(C)C(=O)N2CCCCC2)c1 +COc1ccc(C(C)C)cc1C(=O)N1CCOCC1 +CC1CCc2nc(CN3CCOC(C(N)=O)C3)sc2C1 +COCCC(=O)NC(Cc1cccs1)c1nccs1 +Brc1c[nH]nc1-c1nc(-c2cccs2)no1 +O=C(CCCc1ccc2c(c1)CC(=O)N2)NCC1CC=CCC1 +O=C(NCCNC(=O)c1cccc2ccoc12)Nc1ccccc1 +CC1(NC(=O)NCCC(=O)N2CCCCCC2)Cc2ccccc2C1 +CC(C)C(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2F)CC1 +CN(Cc1ccc(-n2cccn2)cc1)c1nc2c(cc1C(N)=O)CCC2 +COc1ccc(C(=O)NCc2noc(C3CCCCC3)n2)cc1OC +Cc1nc(C)c(C(=O)Nc2cccc(C(F)(F)F)c2)s1 +COc1ccc(-c2ccc(Cl)c(C(N)=O)c2)cc1O +CC(C)n1nnnc1-c1ccc(NC(=O)NCC(F)F)cc1F +CC(C)C(=O)Nc1ccc(SCc2ccccc2F)nn1 +CC1(C(=O)Nc2nc(-c3ccc[nH]3)cs2)CC1(Cl)Cl +CCc1cn[nH]c1C1CCN(c2cncc(C(N)=O)n2)CC1 +NC(=O)c1ccccc1NC(=O)C1CC2CCC1C2 +N#Cc1ccc(SCc2nc(-c3ccncc3)no2)cc1 +COc1cc(C(C)NC(=O)c2c(C)oc(C)c2C)cc(OC)c1OC +Cc1cc(OCC(=O)N2CCN(CCO)CC2)ccc1Cl +Cc1oc2ncn(C)c(=O)c2c1C(=O)NC1CC1c1ccc(F)cc1 +C#CCOCC1CCCN(C(=O)NCCOC)C1 +CCOC(=O)c1nnn2c1SCC(c1ccc(OC)cc1)=N2 +O=C(CN1CCCS1(=O)=O)NC1C2CCc3ccccc3C21 +CCCn1cnnc1CNC(=O)Nc1nc(-c2ccccc2)ns1 +O=c1ccc(-c2nc3c4ccccc4ncn3n2)n[nH]1 +Cc1cc2n(n1)CCCN2C(=O)CCC(=O)NCCc1ccccc1 +COc1ccc(Cl)cc1NS(=O)(=O)c1ccc(C(C)=O)cc1 +CNc1cncc(C2CCN(C(=O)C3CCC3)CC2)n1 +COc1ccc(C(=O)CCC(=O)NC(C)c2c(C)noc2C)cc1 +CC(C(=O)N(C)c1ccccc1)S(=O)(=O)c1nnc(C2CC2)n1C +Cc1cc(C)n(CC(=O)NC2CC(=O)N(Cc3cccc(F)c3)C2)n1 +CCC1c2ccsc2CCN1C(=O)CSc1nnc(C)n1N +CCSc1nc(C)cc(C(=O)Nc2cccc(COC)c2)n1 +CCOc1ccc(F)c(C(=O)Nc2ncn(CC(=O)NC)n2)c1F +COc1ccc(OC)c(C(C)NC(=O)CNc2cccc(C#N)c2)c1 +CCOC(=O)C(C)C1(C(=O)OCC)CCCCC1=O +Cc1cc(C)c(S(=O)(=O)n2cncn2)c(C)c1 +CC(C)CNC(=O)c1cc(-c2ccccc2O)no1 +CNC(=O)C1CCCCN1S(=O)(=O)c1ccc(NC(C)=O)cc1 +Cc1ncoc1C(=O)N1CCOC(CC2CCCCC2)C1 +C=CCNC(=O)Cn1cc(Br)c(=O)[nH]c1=O +O=C(Nc1cc(C(F)(F)F)ccc1N1CCCC1)c1csnn1 +COc1ccc(CC(C)CNC(=O)c2ccc(C)nc2)cc1 +CNC(=O)c1cccc(NC(=O)NCC2CCCC(C)C2)c1C +COCCN(C)S(=O)(=O)c1cc(Br)ccc1N +O=C(NCCc1cc(F)cc2c1OCOC2)N1CCOCC1 +c1ccc(CNc2ccccc2N2CCOCC2)cc1 +Cc1ccc(S(=O)(=O)N2CCOc3ccccc32)cc1C(N)=O +COC(=O)c1ccc(CN2CCc3[nH]ncc3C2)s1 +COc1cccc(C2(Cc3ccc(C)o3)NC(N)=NC2=O)c1 +Cn1cnnc1CNC(=O)c1ccc(NC2CC2)nc1 +CC(O)C(=O)N1CCN(Cc2cccc(-c3ccccn3)c2)CC1 +Cc1csc(N2CCCN(S(=O)(=O)c3cccnc3)CC2)n1 +Cc1nn(C)c(C)c1CCc1nc(-c2ccc(C#N)cn2)no1 +c1ccc(N2CCN(c3nc4ccccc4c4nncn34)CC2)cc1 +CN(CCc1cccc2ccccc12)Cc1ccnn1C +COc1cccc(CNC(=O)Cc2cccs2)c1OC +CCCCN(C)C(=O)Nc1cccc(C(=O)OC)c1 +Nc1cccc(C(=O)OCC(=O)NC2CCCCC2)c1 +O=C(CCCn1cncn1)NC1(c2ccc(Cl)cc2)CCC1 +COc1ccc(C(=O)N(C)CC(=O)N(C)C)cc1OC +COC(=O)c1nsc(C(=O)Nc2cccc(C)c2C)c1N +O=C(c1ccc2c(c1)OCO2)N1CCOC(COc2cccnc2)C1 +NC(=O)CCNC(=O)Nc1cccc(OCc2cscn2)c1 +Cc1nc2ccccn2c1C(=O)Nc1ccc(-n2ccnc2C)nc1 +COc1ncccc1CNC1=NS(=O)(=O)c2ccccc21 +COc1ccc(CNC(=O)C2(c3cccs3)CCCCC2)cn1 +Cc1ccc(C)c(NC(=O)c2cccc(S(C)(=O)=O)c2)c1 +O=C(NCc1nc(-c2cccnc2)n[nH]1)c1ccco1 +O=C(Cc1ccc(NC(=O)c2cnc3cc[nH]c3c2)cc1)NC1CC1 +CCCCC(=O)N1Cc2ccc(C(O)c3ccccc3)cc2C1 +Cc1nc(C)n(C2CCCN(C(=O)COC3CCCC(C)C3)C2)n1 +Nc1ccc2oc(C(=O)Nc3ccccc3F)cc(=O)c2c1 +CC(C)Oc1ccccc1NCCOc1cccc(N)c1 +CN(C)c1cccc(CNC(=O)c2cccc(-n3cccn3)n2)c1 +CCN(CC(=O)OC)C(=O)c1ccc(C(C)C)cc1 +CC(C)CN1CC(C(=O)NC(C)c2nc3ccccc3n2C)CC1=O +Cc1nc2c3c(sc2c(=O)o1)N1CCCC1N=C3 +NC(=O)c1ccc(OCc2ccc(Br)cc2)cc1 +CCCOc1ccccc1NS(=O)(=O)c1ccc(C(C)=O)cc1 +CCN1CCN(C(=O)c2cc(C(N)=O)cs2)CC1 +COc1ccccc1-c1nnc(SC(C(=O)N(C)C)C(C)C)n1N +COc1cc2c(cc1CNC(=O)c1cccc(OC)c1F)OC(C)C2 +Cc1cc(C(=O)N2CCC3C2CC(=O)N3c2cnn(C)c2)[nH]n1 +CC(C)(C)C(NC(=O)c1cccc(-c2noc(C3CC3)n2)c1)C(N)=O +CC(=O)Nc1nc2c(s1)CN(CC(=O)Nc1cccc(F)c1)CC2 +O=C(Nc1cc(Cl)ccc1N1CCCCC1)N1CCC(O)C1 +CCN(CC)C(=O)C1CCCN1C(=O)Nc1ccc(F)cc1Cl +CCCCc1nc(C(N)=O)c2[nH]c(=O)n(-c3cccc(OC)c3)c2n1 +CCC(C)NC(=O)C1CC(=O)CC1C(=O)NC(C)CC +CC(NC(=O)C1CCCCC1)c1nnc2ccccn12 +CC(Cn1cncn1)NC(=O)C1CC(=O)N(C)C1 +COCCCNC(=O)C1(C)CCC(=O)N1Cc1ccccc1F +Cc1ccccc1-n1ccnc1SCC(=O)NCCCO +CCc1onc(C)c1NC(=O)Cc1cccc(OC(F)F)c1 +COc1cccc(-c2noc(C3CCCN(C(=O)C(C)(C)C)C3)n2)c1 +Cc1cccc(OCc2noc(C3CCOCC3)n2)c1F +CN(CCCNC(=O)c1cn2cccnc2n1)c1ccccc1 +Cc1ccc(NC(=O)C2CCCN2C(=O)C(C)(C)C)c(O)c1 +COc1ccc(C)cc1S(=O)(=O)N1CCNC(=O)C1 +COC(=O)C(C)(C)CNC(=O)C1CC1c1ccco1 +O=C(Nc1ccc(-n2cccn2)cc1)c1ccc2c(c1)OCO2 +Cc1cc(S(=O)(=O)Oc2ccc3ccc(=O)oc3c2)ccc1F +CN1CC(c2nc3ccccc3n2CC(O)COC(C)(C)C)CC1=O +CCOc1ccc(Cn2c(=O)[nH]c3ccsc3c2=O)cc1OCC +O=C(Cn1cnc2ccc(F)cc2c1=O)N1CCOC2CCCCC21 +Cc1cc(C)cc(NC(=O)CN(c2ccccc2)S(C)(=O)=O)c1 +CC(C)(COc1ccc(Cl)c(Cl)c1)C(N)=O +CCCc1nnc(SCc2cc(=O)n3oc(C)cc3n2)[nH]1 +CCc1nn(C)c(OC)c1CN1CCCCC1C(=O)OC +CC(C)N(Cc1ccccn1)C(=O)C1CCN(C)C(=O)C1 +O=C(Nc1nonc1NC(=O)c1ccccc1F)c1ccccc1F +CC(=O)Nc1ccc(S(=O)(=O)N2Cc3cncnc3C2)cc1 +CSc1cccc(NC(=O)CCC(=O)c2cccs2)c1 +CCOC(=O)CN(C(=O)c1ccccc1SC)C(C)C +Cc1ccc(C(=O)NC(C(=O)Nc2nccs2)C(C)C)cc1 +CC(C)(C)C(=O)Nc1cccc(NC(=O)CCc2cccc(N)c2)c1 +Cc1ccc(CNC(=O)NCC(C)CN2CCOCC2)c(N(C)C)c1 +COc1ccc(-c2noc(NCc3ccco3)n2)cc1 +CCNC(=O)CN(CC)S(=O)(=O)c1cc2ccccc2o1 +Nc1ccc(F)cc1C(=O)Nc1ccc(F)cc1F +O=C(NCC(O)COCC1CC1)Nc1ccc2c(c1)COC2 +COCCCNS(=O)(=O)c1ccc(-c2cnns2)s1 +CC(C)Cc1nc2oc3c(=O)[nH]cnc3c2c2c1CCCC2 +CCn1nc(C)cc1C(=O)Nc1cnn(Cc2ccc(F)cc2)c1 +O=C(NCCNc1ncccn1)N(Cc1ccc(F)cc1F)C1CC1 +Clc1ccc(NCc2csnn2)cc1Br +O=C(Nc1ccc(Cl)c(-c2nc3ncccc3o2)c1)C1CC1 +CCn1c(CNc2ncccc2S(N)(=O)=O)nc2ccccc21 +Cc1cc(C(C)NC(=O)c2cnn[nH]2)c(C)s1 +CCCC(=O)N1CCCC(C(=O)NC2(C)Cc3ccccc3C2)C1 +Cn1c(=O)oc2ccc(C(=O)Nc3ccc(Cl)cc3)cc21 +Cc1cccc(OC(C)C(=O)Nc2ccc3c(c2)OCO3)c1 +Fc1ccc(-c2noc3ncnc(NCc4ccccn4)c23)cc1 +Cn1ccnc1SCCn1ccnc1-c1cccc2nonc12 +CCC(C)n1cc(C(=O)NC2CC2)c(=O)c2c(N)cccc21 +COc1ccc2ccn(CC(=O)Nc3ccc(F)c(F)c3)c(=O)c2c1 +O=C(Cc1ccc(F)cc1)c1c(O)cc(O)cc1O +CSc1ccc(CNS(=O)(=O)c2ccccc2Cl)cc1 +Cc1n[nH]c(C)c1C(=O)NCC(C)(C)c1ccccc1 +O=C(Cc1cccc2ccccc12)N1Cc2cncnc2C1 +O=C(NCCc1ccccc1)NCCC(O)c1ccccc1 +CC(C)c1nc(C(C)NC(=O)Cc2ccc(F)cc2)cs1 +CCCC(=O)c1ccc(S(=O)(=O)NC(C)(C)CO)cc1 +Cc1cccc(-c2nn(C)c(=O)o2)c1S(N)(=O)=O +Cn1ccc2ccc(C(=O)NCCSc3ccccn3)cc21 +CCN(CC)C(=O)c1cc2ccccc2cc1NC(=O)C1CC1 +Cc1cc(C(=O)N(C)Cc2ccncc2)c(C)n1Cc1ccccc1 +CCn1nc(NC(C)=O)c2cc3cccc(C)c3nc21 +COc1ccc(-c2nc(C)c(C(C)NC(=O)CNC(N)=O)s2)cc1 +COCCN1CCN(C(=O)c2ncoc2-c2ccccc2Cl)CC1 +O=C(Nc1ccccc1C(F)(F)F)c1ccc(-n2ccnn2)cc1 +CN(Cc1nnc2ccccn12)C(=O)Nc1ccc(OCC#N)cc1 +O=C(NCCn1ncccc1=O)Nc1ccc(F)c(F)c1 +COc1cccc(N2CCN(C(=O)CCc3ccco3)CC2)c1 +Cc1cc(N)nc(SC(C)C(=O)NC2CCCC(C)C2C)n1 +CN(C)c1cc(-n2cnc(C(=O)NCc3ccccn3)c2)ncn1 +Cn1c(SCC(=O)N2CCCCC2)nnc1C1CC1 +CC(=O)Nc1c(C#N)c(C)nn1-c1nc(C)cc(C)n1 +COc1ccc(CCNS(=O)(=O)Cc2ccccc2C)cc1 +CNC(=O)NCC(=O)N1CCC(C(=O)c2ccc(Cl)cc2)CC1 +O=C1COc2cc(C(=O)OCC(=O)c3ccc(F)c(F)c3)ccc2N1 +O=C(NCc1cccc(N2CCOC2=O)c1)c1ccccc1O +COC(=O)c1ccc(CN(C)C(=O)c2ccsc2)cc1 +O=C(CSc1nc2ccccc2[nH]1)c1ccc2c(c1)OCO2 +Cc1nc(C)c(COC(=O)C(C)c2cccs2)s1 +Cc1cc(NC(=O)c2cccc(-n3cccn3)n2)ccc1F +O=C(NCCCN1CCOCC1)c1cccs1 +Cc1cccc(OCC(C)NC(=O)c2ccc(C)nc2C)c1 +CN(C)S(=O)(=O)N(CC(=O)N1CCOCC1)c1ccccc1F +O=C(NCCc1ccccn1)c1occc1-c1ccccc1 +CCc1ccc(CNC(=O)COC(=O)c2ccccc2F)cc1 +C#CCOc1ccc(NC(=O)N2CCc3cc(F)ccc3C2)cc1 +Cc1cccc(C(=O)OCC(=O)N(C(C)C)C(C)C)c1C +Cc1ccc(OCC(=O)N2CCCCC2C2OCCO2)cc1 +Cc1n[nH]c(C2CN(C(=O)c3cc(C)n(C(C)C)c3C)CCO2)n1 +COc1cccc(C(CC(=O)NC2CC2)c2c[nH]c3ccccc23)c1 +Cn1c(N)nnc1SCC(=O)Nc1ccccc1C(F)(F)F +CCOC1CC(NC(=O)Cc2cccc(OCC#N)c2)C12CCCC2 +NC(=O)C(OC(=O)Cc1noc2ccccc12)c1ccccc1 +Cc1cc2nc(CNC(=O)c3cnn4c3CCCC4)[nH]c2cc1C +Cc1[nH]nc(NS(C)(=O)=O)c1-c1cccc(Cl)c1 +COC(=O)CN(Cc1ccccc1C)C(=O)C1CCC1 +Cc1ncsc1C(=O)Nc1cnn(-c2ccccc2Cl)c1 +COc1cccc(NCc2ccc(OC)c(Cn3ccnc3)c2)c1 +CC(C)CC(C)n1nccc1NC(=O)NCCN1CCOCC1 +COc1cc(C)c(C)cc1C(=O)C1CCCN1S(C)(=O)=O +CCOc1ncccc1CNC(=O)N1CCc2ccc(O)cc2C1 +O=C(c1cnc(Nc2ccccc2)nc1)N1CC(c2ccncc2)C1 +CC(NC(=O)c1nccc2ccccc12)c1nc(-c2ccncc2)n[nH]1 +CC(OC(=O)c1nccnc1N)C(=O)NC1CC1 +Cc1ccc(Cl)c(OC(C)(C)C(=O)NCc2ccccn2)c1 +COCSc1nnc(N2CCOCC2)n1-c1cccc(F)c1 +Cc1c(C(=O)OCC(=O)NC(C)C)cnn1-c1ccc(F)cc1 +O=C1Oc2nc3ccccc3cc2CN1Cc1ccc(F)cc1 +Cc1cccc2sc(NC(=O)c3ccc(S(C)(=O)=O)cc3)nc12 +CNS(=O)(=O)c1cc(C(=O)N(C)Cc2ccco2)n(C)c1 +Cc1cc(NC(=O)c2ccn(COc3ccc(F)cc3F)n2)no1 +COc1cc(OC)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)cc1OC +CC12CCC(C(=O)N3CCN(c4ccccc4)CC3)(OC1=O)C2(C)C +O=C(Nc1ccncc1)N1CCCC(C(=O)N2CCOCC2)C1 +CN(CCCC(=O)N1CCC(O)C1)S(=O)(=O)c1cccs1 +COC(=O)c1cc(NC(=O)c2cccc(OC)c2F)ccc1C +COC(=O)C1(NS(=O)(=O)c2cnn(C)c2)CCC(C)CC1 +O=C(CSc1n[nH]c(=O)n1CCc1ccccc1)N1CCCCC1 +N#Cc1ccc(NC(=O)c2csc(Nc3ccccn3)n2)cc1 +Cc1ccc(OCC#CCNC(=O)Cc2noc3ccccc23)cn1 +Cc1ccc(N2CCCS2(=O)=O)cc1NC(=O)C1CC1 +Cc1ccc(NC(=O)CSc2nnc(Cn3cncn3)o2)cc1 +Cc1ccc(Nc2nccc3n[nH]c(=O)n23)cc1F +Cc1cc(OCc2ccc(C(=O)N3CCOCC3)o2)ccc1Cl +CCOC(=O)CN(C)C(=O)COc1cccc(Cl)c1 +O=C(OCCN1CCCC1=O)c1ccc(-c2ccccc2F)s1 +CC(C)(C)OC(=O)Nc1ccc(C(=O)N2CCC(=O)CC2)cc1 +CSc1ccc(CNc2ncccc2C#N)cc1 +Cc1[nH]ccc1C(=O)N1CCC2(CCC(=O)N(CCCO)C2)CC1 +O=C(NCCCn1cccn1)C1CC(=O)N(c2ccc(F)cc2F)C1 +CN1CCn2c(nc3cc(C(=O)NC4CCCCC4)ccc32)C1 +COC(=O)Cn1ccnc1Cc1cnn(-c2ccccc2)c1 +CC(OCC1CC1)C(=O)N(Cc1cccnc1)c1ccc(F)cc1 +O=S(CCN1CCOc2ccc(F)cc21)c1ccccc1 +Cc1ccc(Br)cc1NC(=O)CCNC(=O)C1CC1 +Cc1nc(CN2C(=O)CC3C2CCN3C(=O)c2conc2C)cs1 +CN(C)c1cccc(C(=O)Nc2cnc(N3CCCCC3)nc2)c1 +Cc1nn(C)c(C(=O)NC(C)CN2CCOCC2)c1Cl +CC(=O)c1ccc(NC(=O)c2cnc(-c3cnn(C)c3)s2)cc1C +CC(Sc1nnc(-c2ccncc2)o1)C(=O)N(C)C1CCCCC1 +CC1(C)CC2(CCOC(c3ccccc3)O2)CCO1 +CCC1CCCCN1C(=O)CCS(=O)(=O)c1ccc(Cl)cc1 +CC(OC(=O)CNC(=O)CC(C)(C)C)c1ccc(F)cc1F +CN(C(=O)c1cn(C)nc1C(F)(F)F)c1ccccc1 +Cc1nc(C2CCCC2)sc1C(=O)OCC1CC(=O)N(C2CC2)C1 +COc1cccc(C2CN(Cc3cccn3C)CCO2)c1 +Nc1ccc2oc(C(=O)Nc3cccnc3)cc(=O)c2c1 +C=CCNC(=O)c1ccc(NC(=O)Cc2ccc(C)nc2)cc1 +COC(=O)C(C)CN(C)C(=O)c1ccc(Br)cn1 +O=C(Cn1nnc2c(cnn2-c2ccccc2)c1=O)NC1CC1 +O=C(COc1ccccc1F)NC1CC2CCC1C2 +CCOc1cc(C(=O)Nc2cnc3cc(OC)ccc3c2)[nH]n1 +Cc1cccc(CCCOC(=O)c2cccc(C#N)c2)n1 +COc1ccc(OCCNC(=O)NC(C)c2nccs2)cc1 +C=CCOc1ccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3)cc1 +COc1cc2nc(-c3ccccc3OC)[nH]c2cc1OC +Cn1cc(C2CC2C(=O)N2CCCCC2Cn2cccn2)cn1 +CC(C)(C)NC(=O)CCCc1c[nH]c2ccccc12 +CSc1nc(N)nc(SCC(=O)c2ccc(F)cc2)c1C#N +Cc1cc(O)n(CCCN2CCCC2=O)c(=O)c1C#N +CCCc1ncc(C(=O)Nc2cccc(-c3cn[nH]c3)c2)s1 +COc1cc(C2NCCc3c(OC(C)C)cccc32)ccn1 +O=C(c1cc2c(s1)CCC2)N1CCC(c2nnc3n2CCC3)CC1 +CN(C(=O)Cc1cc(Cl)c2c(c1)OCCO2)c1cccc(C#N)c1 +CC(CC(O)c1ccccc1)NC(=O)c1cccc2cc[nH]c12 +CCOCC(=O)Nc1ccccc1C(=O)N(CC)CC +CC1COCC(C)N1C(=O)Cc1cc(Cl)c2c(c1)OCCO2 +Cc1n[nH]c(C(=O)NCC2CCCOC2)c1Br +CC(C(=O)N1CCc2ccccc2C1)n1ncc2ccccc21 +COc1cc2c(=O)[nH]c(C3CCCCC3)nc2cc1OC(F)F +Cc1ccc(NC(=O)c2cc3cccnc3[nH]c2=O)cc1C +CC(O)CNC(=O)C(C)Oc1cccc(C(C)(C)C)c1 +COc1ccccc1C(C)N(C)C(=O)CCc1c(C)[nH]c(=O)[nH]c1=O +CCCOC1CCCN(S(=O)(=O)c2cnc3ccsc3c2)C1 +Nc1cc(F)cc2c1CCNC2c1ccc(F)cc1F +Cc1n[nH]c(NC(=O)c2cccc(CC#N)c2)c1C +O=C(CSc1ncn[nH]1)Nc1ccc(F)cc1F +CN(C(=O)c1ccc(NC(=O)COCC2CC2)cc1)C1CCCCC1 +CN1CCN(C(=O)C2CN(C(=O)Cn3nnc4ccccc43)C2)CC1 +CCc1ccc(N2CC(C(=O)NCc3ccccc3)CC2=O)cc1 +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1noc2c1CCCC2 +O=C(Cc1cccs1)NC1CCN(C(=O)Nc2ccccc2)CC1 +CCn1nc(C)c(-c2ccnc(NCC3(CO)CC3)n2)c1C +O=C(Cn1ccc(C(F)(F)F)n1)Nc1ccc(Cl)cn1 +Nc1ccc(-c2cnnn2CCOc2ccc(Cl)cc2)cc1 +CCn1c(SCC(=O)Nc2cn[nH]c2)nnc1-c1ccccc1C +COCCN1CCN(C(=O)NC2CCCCC2C)CC1=O +Cc1nc(C(=O)Oc2cccc(C(N)=O)c2)cs1 +Cn1cncc1C(=O)N1CCc2c(nc(-c3ccccc3)[nH]c2=O)C1 +O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)Nn1cnnc1 +O=C1CCCN1C1CCN(c2cc(N3CCOCC3)ncn2)CC1 +CCN(Cc1cccc(C)c1)C(=O)c1ccc(F)c(NC(C)=O)c1 +CCCCS(=O)(=O)N1CCC(Cn2cnc3ccccc32)CC1 +COc1cccc(NC(=O)Nc2ccn(-c3ncccc3Cl)n2)c1 +Cc1ccc(C#N)cc1NC(=O)c1cc(C(C)C)[nH]n1 +O=C(c1ccc(-c2ccccc2F)o1)N1CCCC(n2cccn2)C1 +CCOC(=O)c1nc[nH]c1C(=O)NC1CCCCC1 +O=C1CCN(Cc2ccc(Sc3ccccc3)cc2)CCN1 +CCOC(=O)N1C2Sc3cccnc3C1Sc1ncccc12 +COCCNC(=O)c1cn(C)nc1S(=O)(=O)N1CCCCCC1 +CCC(=O)N1CCCCC1C(=O)Nc1cc(-c2ncco2)ccc1C +Cc1ccc(S(=O)(=O)NCCC(=O)N2CCc3ccccc32)cc1 +O=C(NCC1(Cn2cccn2)CC1)c1ccc(C2CCCO2)s1 +CSc1cncc(NC2CCCC2(C)CO)n1 +CC1CN(CC2CCCN2C(=O)Nc2nncs2)CC(C)O1 +COc1ccc(NC(=O)NC(C)c2cc(C)oc2C)c(OC)c1 +N#Cc1ccc(OCC(=O)N2CCCC2c2ccccc2)cc1 +O=C(CCS(=O)(=O)c1ccc2c(c1)OCCO2)NC1CC1 +Cc1cnc(C(=O)OCc2nc(-c3ccc(C)c(F)c3)no2)cn1 +CCOc1ccc2c(c1)sc1nc(=O)n(-c3ccccc3)c(=O)n12 +Cc1ccc(CN2CC(C(=O)N(C)C(C)c3ccco3)CC2=O)cc1 +COC(=O)NCC(=O)Nc1nnc(C(C)C)s1 +COc1ccc(N)cc1C(=O)OCC1CCOC1 +Cc1ccccc1CN1CC2CC(C(=O)Nc3ccccc3)C(C1)O2 +CC(Sc1nccn1C)C(=O)Nc1cccc(C(F)(F)F)c1 +Cc1cc(NC(=O)NCc2cnn(C)c2)ccc1Oc1cccnc1 +O=C(c1cc(C2CC2)[nH]n1)N1CCN(Cc2ccccc2F)CC1 +CC1(C(=O)NCCc2ccccn2)Sc2ccccc2NC1=O +Cc1nn(C)c2nc(N3CCCCC3CCn3cccn3)sc12 +CN(CCOc1ccccc1Br)CC(F)F +O=C(Nc1ccccc1)C1CC(=O)n2c(nc3ccccc32)N1 +Cc1cc(C)c(C(=O)NCCCNC(=O)OC(C)(C)C)c(C)c1 +CNC(=O)CC1c2ccccc2CCc2ccccc21 +CCCC1(CO)CCCN(C(=O)CCN2CCCC2=O)C1 +Cn1nnnc1SCC(=O)Nc1ccc(F)c(F)c1F +COc1ccc(C(C#N)c2ccc(N)cn2)cc1Cl +O=C(NCc1ccccc1COCC1CC1)c1ccn2nccc2c1 +CCc1nc(CN2CCCC(c3noc(C4CC4)n3)C2)cs1 +Cc1cc(C)n(CC(C)CNC(=O)Cc2ccc(F)c(F)c2)n1 +O=C(Nc1ccccc1Cl)N1CCOC2(CCOCC2)C1 +COc1cc2c(cc1CNC(=O)c1ccco1)OCCCO2 +COc1ccc(NC(=O)COCC2CC2)c(N)c1 +Cn1cc(Cl)c(C(=O)NC(c2ccccn2)C(F)(F)F)n1 +O=C(NCCNS(=O)(=O)Cc1ccccc1)c1ccccc1 +CC(C)(CNC(=O)c1cccnc1OCC(F)F)C(N)=O +O=C(Cn1nnc(-c2ccc(Cl)cc2)n1)Nc1c(F)cccc1F +COC(=O)c1cc(-c2ccncc2)nc(N2CC(C)OC(C)C2)n1 +CN(Cc1c[nH]nc1-c1cccs1)CC(F)F +Cc1ccc(C2CN(C(=O)NCC#Cc3ccccc3)CCO2)o1 +O=C(NCS(=O)(=O)c1ccccc1)c1ccccc1 +CN(C)C(=O)Cc1ccc(NC(=O)C2CC3CCC2O3)cc1 +CC(NC(=O)c1cccc2[nH]ccc12)c1ccc(C#N)cc1 +N#Cc1ccc(S(=O)(=O)Oc2ccc(F)cc2Cl)cc1 +O=C(OC1(C2CCOC2)CC1)c1ccc(-n2cncn2)cc1 +CC(C)(C)c1ccc2cc(C(=O)NCC3COCCO3)[nH]c2c1 +Cc1cc(NC(=O)N2CCc3sccc3C2)ccc1-n1cnnn1 +COc1ccc2c(cnn2CCC(=O)NCc2cccnc2)c1 +Cc1ccc(CNC(=O)c2nccnc2N)c(OCC2CC2)c1 +COc1cccc(NC(=O)c2nnn(-c3ccc(F)cc3)c2C)c1 +O=C(NCCc1nc2ccccc2[nH]1)c1cc2c(cc1O)OCO2 +O=C(Nc1cnc2ccccc2c1)N1CCCCC1 +O=C(Cc1cccs1)Nn1nnnc1Nc1ccccc1 +O=C(NCc1cccnc1)Nc1ccc(Oc2cccnc2)nc1 +NS(=O)(=O)CCNC(=O)c1cc(C2CCCCC2)n[nH]1 +CC(C)OCCCNC(=O)C1CCN(S(C)(=O)=O)CC1 +OCc1cc(-c2ccc(F)cc2)oc1C(F)(F)F +O=c1nc2ccccn2c2ccc(S(=O)(=O)N3CCCCC3)cc12 +CC(C)(C)c1csc(CNC(=O)c2ccc(C#N)cc2)n1 +CC(C)(C)OC(C(=O)NCc1csc(=O)[nH]1)c1ccccc1 +CCCOc1cccc(NCc2cc(C#N)n(C)c2C)c1 +CCOc1ccc(-c2csc3nc(C)nc(NCC(C)O)c23)cc1 +Nc1cc(-c2nnc3sccn23)ccc1Cl +Fc1ccc(N2CCOC3(COCCN(c4ncccn4)C3)C2)cc1 +CCOc1ccc(OC)cc1NCc1noc(C(C)C)n1 +CCc1cc(N2CCCC(CO)C2)nc(-c2ccncc2)n1 +Cc1cccc(NC(=O)NCC(=O)NCCCO)c1 +CC(=O)c1nc2cccnc2n1Cc1cccc(Cl)c1 +O=C(c1cncs1)N1CCC(c2ccccn2)CC1 +COC(=O)c1ccc(C)c(NC(=O)CSc2ncccn2)c1 +COc1cccc(NC(=O)CNC(=O)CCC2CCCC2)c1 +CCOc1cc(=O)oc2ccc(Br)cc12 +CN(C(=O)c1cnc(-c2ccccc2)nc1)c1cc(F)ccc1F +CC(CNCc1ccccc1C#N)Oc1ccccc1 +O=C(c1cccc(F)c1)N1CCC(c2nnc(C3CC3)o2)CC1 +Cn1cnnc1Cn1ccc2ccn(Cc3ccccc3F)c2c1=O +CCNC(=O)C1(NCc2ccsc2C(=O)OC)CCCCC1 +CC(CC(=O)Nc1cccc(O)c1)NC(=O)c1ccccc1 +N#Cc1ccc(NC(=O)c2cccc(F)c2)cc1Cl +CCc1ccc(NC(=O)CC(C)(C)C)cc1S(N)(=O)=O +CC(=O)NC1(C(=O)N(C)CC(C)C#N)CCCCC1 +Cc1cc(=O)[nH]c2cc(NC(=O)C3CCC3)ccc12 +CCC(=O)c1cccc(NC(=O)Cc2cccc(OCC#N)c2)c1 +N#Cc1ccc(-c2ccc(F)cc2)n(CC(O)CO)c1=O +O=c1[nH]ncc(NCCCOC2CCCC2)c1Cl +CCCCN(C)c1cnn(-c2ccccc2C(=O)OC)c(=O)c1Cl +Cc1nn(C)c(C(=O)Nc2sc(C)c(C)c2C#N)c1Cl +C=CCNC(=O)c1nccc2c(N)cc(Cl)cc12 +Cc1ccc(C(N)=O)cc1NCC(=O)NC1(C#N)CCCC1 +O=C(CC1CCCC1)N1CCC(c2cc3ncccc3c(=O)[nH]2)CC1 +CC1c2ccsc2CCN1C(=O)Cn1nnc2ccccc21 +COC(=O)c1nc2ccc(Cl)cn2c1NCc1ccccc1 +Cc1n[nH]cc1CNc1ncc(Cl)cc1Cl +Cc1ccc(-n2cnnc2SCC(=O)c2cccn2C)cc1Cl +CCc1cnc(CN(C)C(=O)c2c[nH]nc2-c2ccccc2F)s1 +O=C(Cn1cncn1)NCC1(c2ccc(F)cc2)CCCCC1 +O=C(NCCC1CCCO1)c1ccc(-c2ccccc2)[nH]c1=O +Cc1cc(NCc2ccc(OC(C)C)c(F)c2)n2ncnc2n1 +Cc1ccc2nc(CN3CC(C)OC(C)C3)[nH]c2c1 +O=C(Cc1cccnc1)Nc1ccc(NC(=O)c2ccco2)cc1 +CC(=O)N1CCN(c2ncc(-c3cnccn3)c(C3CC3)n2)CC1 +Cc1ccc(NS(=O)(=O)c2cccc(C(=O)NCC3CC3)c2)cc1 +CSc1nc(C(C)C)nc(C)c1C(=O)N1CCOC2CCCCC21 +CC(=O)N1CCN(C(=O)CNc2ccc(-n3nccn3)cc2)CC1 +CCc1onc(C)c1NC(=O)C(C)OCCC(C)C +COc1ccc(C(O)c2cccc(Cl)c2)cc1OC +CC(=O)NCCNC(=O)Nc1ccc2c(c1)CCC(=O)N2 +CC(c1ccccc1F)N(C)S(=O)(=O)Cc1ccccc1 +CCCC(=O)N1CCN(c2cnn3c(C)nnc3c2)CC1 +CC(C)(C)c1ccc(N2CCCS2(=O)=O)cc1 +NC(=O)C1CCN(S(=O)(=O)CCn2cnc3ccccc32)CC1 +COC1(C)CC(NC(=O)NCc2cccc(-n3cncn3)c2)C1(C)C +NC(=O)C(NC(=O)C1CCOCC1)c1cccc(Br)c1 +Cc1ccccc1NC(=O)COC(=O)c1ccc(C#N)cc1 +CC1CN(C(=O)CCN2C(=O)CCc3ccccc32)C(C)CO1 +Cc1occc1NC(=O)Nc1ccc(Cl)cc1 +O=C(NCc1ccc(F)cc1)c1ccc(N2CCOC2=O)cc1 +CS(=O)(=O)N1CCC(NC(=O)NCc2ccccc2F)CC1 +CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)CC(=O)C1 +Cc1cc2c(NCCc3c[nH]c4ccccc34)ncnc2s1 +Cc1ccsc1C(=O)NCC1CN2CCCCC2CO1 +Cc1ccc(NC(=O)Nc2cc(C(=O)N(C)C)ccc2C)cc1 +O=c1c2sccc2ncn1CCSc1cccs1 +CN(CC(=O)NC1CC1)C(=O)CSc1ccc2ccccc2c1 +Cc1ccc(C(N)=O)c(OC(=O)C=C2CCCCC2)c1 +COc1cccc(-c2nc(C(C)(C)NC(C)=O)no2)c1F +Cc1cc(F)cc2c1CCNC2C1COc2ccccc2O1 +Cc1nn(C)c(-c2nc3c4c(C)c(C)sc4ncn3n2)c1Cl +Nc1cc(N)c(Br)cc1Br +Cn1cc(C(=O)COc2ccccc2)c2ccccc21 +C=C(C)CN(CC)C(=O)NCCNC(=O)c1cccnc1 +CCN(C(=O)CCCn1ccc2cc(Cl)ccc21)c1cccnc1 +Cc1ccn(C(C)CC(=O)Nc2cccc(C)c2C)n1 +Cc1cccc(NC(=O)C23CCC(C2)C(C)(C)C3=O)c1 +Cc1cc(C)n2nc(C(=O)N3CC(C)C(N4CCOCC4)C3)nc2n1 +CC(NC(=O)NCCc1cnn(C)c1)c1ccc2c(c1)OCCO2 +CCC(C)NS(=O)(=O)c1cccc(C(C)O)c1 +CN(Cc1ccccn1)C(=O)Cn1c(C(F)(F)F)nc2ccccc21 +Cc1nn(CC(=O)N(C)C(C)C)c(=O)c(C#N)c1C +COc1ccc(CCNC(=O)N2CCOC(C(F)(F)F)C2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)NC(C)Cc1ccc(C)s1 +C#CCNCC(=O)NCCc1ccc(Cl)cc1 +COc1cccc(CCNC(=O)C2CC2c2ccccc2C)c1O +COC(=O)c1c(F)cccc1NCc1nnc(C2CC2)o1 +NC(=O)C1CCN(C(=O)C2(c3ccc(Cl)cc3)CCOCC2)C1 +Cc1nc(C)c(-c2nnc(NC(=O)c3ccccc3C)o2)s1 +CCN(Cc1ccccc1)S(=O)(=O)c1ccc(N)cc1 +CCOC1CCN(S(=O)(=O)c2ccccc2)C1Cc1cnn(C)c1 +COCCNC(=O)Nc1cc(C(N)=O)ccc1C +CS(=O)(=O)N1CCCC1C(=O)NCc1ccco1 +Cc1ccc(C(=O)NC(C)c2ccc(N)cc2)cc1C +Cc1cc(CSc2ccccc2C(=O)NCC2COCCO2)on1 +Cc1c(C(=O)OCCNc2cccnn2)cnn1-c1ccccc1F +O=C(COC(=O)c1ccccc1O)NCc1ccccc1Cl +Cc1c(C(=O)N2CCc3ccccc3C2)sc2ncn(C)c(=O)c12 +CCOC(C)c1noc(CSc2nc(CC)n[nH]2)n1 +CC(C)CCNC(=O)c1cccc(-c2nnnn2C(C)C)c1 +CN(C(=O)c1cccc(CC#N)c1)c1ccc(O)cc1 +CCN(CC)C(=O)CNC(=O)Nc1ccn(-c2ccccc2)n1 +Cc1nc(-c2ccncc2)sc1C(=O)Nc1nc2c(s1)CCC2 +O=C(CSc1nnnn1-c1ccccc1)NCc1cccs1 +COc1ccc(OC)c(C(=O)Nc2ccccc2OC)c1 +Cc1cnc(NC(=O)c2cccc(NC(=O)c3cccs3)c2)s1 +CC(=O)Nc1ccc(S(=O)Cc2ccc(C(=O)N(C)C)cc2)cc1 +CCOCC(O)CN1CCN(C(=O)C2CC=CCC2)CC1 +NC(=O)C(CNC(=O)Cc1ccc(F)cc1)Cc1ccccc1Cl +O=C(Nc1cccc(-c2nnco2)c1)c1ccccc1 +COc1ccc(-c2csc(NC3CC3)n2)cc1F +Cc1nc2ccc(NC(=O)c3cc4ccccc4oc3=O)cc2s1 +CC(C)n1ncc(S(=O)(=O)NC2CCCCCC2)c1N +CC(=O)NC1(C(=O)N2CCCC(c3ccn[nH]3)C2)CCC(C)CC1 +CN(C)C(=O)c1cc(O)c2cc(C(C)(C)C)ccc2c1 +CCC(C)Sc1nnc(NC(=O)C(C)CC)s1 +COc1ccc2c(c1)OCC(C1Nc3ccccc3C(=O)N1C1CC1)=C2 +CCCN(CCc1cccc(F)c1)Cc1ccnn1C +Cc1ccc(CN(C)C(=O)CCc2ccc(C#N)cc2)o1 +NC(=O)C1CCN(C(=O)c2ccc3c(c2)CCCC3)CC1 +O=C(c1cn2ccsc2n1)N1Cc2cnn(CCO)c2C1 +CC(=O)N1CCC(Cc2cncc(-c3ccc(F)c(F)c3)n2)CC1 +COC(=O)c1cc(Cl)c2c(c1O)C(=O)OC(C)C2 +Cc1ccccc1-c1cc(=O)n2ncc(C(C)C)c2[nH]1 +CCOc1cccc(C(=O)N(Cc2ccco2)Cc2cccs2)c1 +CN(C)C(=O)C1CCCN1C(=O)c1cccc(N2CCCC2=O)c1 +COc1ccc(C(=O)N(C)Cc2nnc3ccccn23)c(OC)c1 +O=C(Nc1ccncc1)C1(c2cccc(Br)c2)CC1 +Nc1oc(-c2ccncc2)cc1C(=O)c1ccccc1 +O=C(c1cccc(COC(=O)C2(O)CCCC2)c1)N1CCCCC1 +COc1ccc(CNC(=O)c2nn(C)c3ccc(F)cc3c2=O)cc1 +O=C1CC2C(CCN2C(=O)c2ccsc2)N1Cc1cccnc1 +Cc1ccc2c(c1)C(NC(=O)c1c[nH]c(=O)cc1C)C(C)C2 +CCc1n[nH]c(Sc2c(N)cc(C(=O)OC(C)C)cc2Cl)n1 +CC(=O)c1cc(Br)ccc1OCc1noc(C2CC2)n1 +CCN(CC)S(=O)(=O)NCCc1cccc(F)c1 +CCc1cccc(OC(=O)c2ccc(C(N)=O)nc2)c1 +CC(C)(C)c1ccc(CSc2nncc(=O)n2N)cc1 +COC(=O)c1cccc(NC(=O)c2cc3ccc(OC)cc3[nH]2)c1 +O=C1CCC(C(=O)NCc2ccc(Cl)cc2Cl)N1 +CNC(=O)Nc1ccccc1C(=O)N1CCOCC1 +O=C(NC1CCC2CCCC21)c1cc(-c2ccccn2)n[nH]1 +Cc1cc2oc(=O)cc(CNC(C(N)=O)C(C)O)c2cc1C +C=CCNS(=O)(=O)c1cccc(C(=O)NCc2ccccn2)c1 +COc1ccc(F)cc1NC(=O)NCC1(C(C)C)CC1 +N#Cc1cccc(S(=O)(=O)N2CCCC2c2ccccc2)c1 +CC(CCc1ccco1)N(C)S(=O)(=O)c1csc(C(N)=O)c1 +Cc1occc1C(=O)Nc1cc(NC2CC(C)OC2=O)ccc1F +Cc1cccc2[nH]c(CCN(C)C(=O)c3cccc4ccnn34)nc12 +Cc1c(N)cccc1S(=O)(=O)NCCC(N)=O +COC(=O)c1cccc(NCc2noc(-c3ccoc3)n2)c1 +O=C(CCc1nnc(C2CCCCC2)o1)NCc1ccsc1 +NC(=O)c1n[nH]c2ccc(NC(=O)C3CC34CCOCC4)cc12 +COC(=O)c1ccc(C(=O)NCCCn2cccc2)cc1 +COc1cc(OC)c2[nH]c(C(=O)OC(C)C(=O)NC(C)(C)C)cc2c1 +CN(Cc1c(F)cccc1Cl)C(=O)CCCO +COc1cc(C(=O)N(C)Cc2cccc(OC)c2OC)ccc1C +CNC(=O)Cc1ccc(NC(=O)CCOC(C)C)cc1 +CCNC(=O)c1ccc(-c2ccc(S(C)(=O)=O)cc2)nc1 +C#CCN(Cc1ccc(C)cc1)C(=O)NCCCNC(C)=O +CCOC(=O)Nc1cccc(C(=O)Nc2cccc(NC(C)=O)c2)c1 +CCn1nc(CC(C)C)cc1C(=O)N1CCCC1Cn1cccn1 +CC(NCc1nc(C2CC2)no1)c1cn(-c2ccccc2)nn1 +Cc1cc2cc(C#N)c(NCCNC(=O)C3CCCO3)nc2cc1C +CCN(CC)S(=O)(=O)c1nc2nc(C)cc(C)n2n1 +CC(NC(=O)C1CCC1)C(=O)Nc1cc(Cl)ccc1N(C)C +CN(CCC(=O)OC(C)(C)C)C(=O)Nc1ccc2c(c1)COC2 +CC(C)CNC(=O)CN(C)S(=O)(=O)c1cccs1 +CC(=O)N(C)CC(=O)Nc1ccc2c(c1)nc(C(C)(C)C)n2C +CCN(Cc1cccc(NCc2cccc3cccnc23)c1)C(C)=O +Cc1cnn(CCC(=O)N2CCc3ccc(Cl)cc3C2)c1 +CC(NS(=O)(=O)c1ccc(F)c(Cl)c1)C(=O)N1CCCCC1 +CCn1c2ccccc2c2cc(NC(=O)C3CCC(=O)N3)ccc21 +CC(=O)Nc1ccc(NCC(=O)N2CCCCCC2)cc1 +C#CCN1CCN(C(=O)NC(C)c2ccc(S(C)(=O)=O)cc2)CC1 +Cc1cc(S(N)(=O)=O)sc1C(=O)NC1CCc2ccccc21 +COc1cccc(C(=O)N(C)C(C)c2sc(C)nc2C)c1F +O=C(c1cc(Br)c[nH]1)N1CCCC1c1cccs1 +CC(C(=O)Oc1ccc(F)cc1)n1c(=O)oc2ccccc21 +CN(c1cccc(F)c1)S(=O)(=O)c1ccc(C#N)cc1 +Cc1ccc(CNc2cccc(-n3cccc3)c2)o1 +CN(C(=O)c1cccc2nscc12)C1CCCCC1 +Cc1ccc(OCc2nc3ccccc3n2CC(=O)NC2CC2)cc1 +Cn1c(=O)n(Cc2ccccc2Cl)c2ccccc21 +CC(C)(C)OC(=O)NCC(=O)N1CCCC1c1ccccc1 +CN(CC(O)C1CC1)C(=O)CNC(=O)N1CCc2ccccc2C1 +O=C(c1cccc(F)c1)N1CCCC1c1n[nH]cc1-c1ccncc1 +CCC(=O)N1CCCN(C(=O)NCC2(c3ccccc3)CC2)CC1 +Cc1ccc(CC(=O)N2CCc3ccccc3C2)cc1 +CCn1cnnc1CCNc1cc(C)c(C#N)c2nc3ccccc3n12 +CC(=O)NC1CCCN(C(=O)c2ccccc2SCC=C(C)C)C1 +CC(NC(=O)c1csnn1)C(=O)NCc1ccco1 +CC(=O)c1c[nH]c(C(=O)NC2CCCc3c2cnn3C)c1 +COCc1nnc(NC(=O)CSc2nc3ccccc3o2)o1 +CCCOc1cccc(NC(=O)CN(C)S(C)(=O)=O)c1 +CC1=C(C(=O)OC(C)C)C(c2c[nH]c3ccccc23)NC(=O)N1 +N#Cc1cc(C#N)c(SCC2CCCCC2)nc1N +CC(=O)c1cccc(NC(=O)c2ccc(-n3cncn3)nc2)c1 +Cn1nc(-c2cccs2)cc1C(=O)Nc1ccc2cc[nH]c2c1 +CN(Cc1nc2ccccc2n1C)C(=O)c1cccc(-n2cccn2)n1 +Cn1ccc(CNC(C(=O)N2CCOCC2)c2ccccc2)cc1=O +CC(C)n1ncc(S(=O)(=O)NC2CCCCC2)c1N +N#Cc1ccc(NCc2ccc(S(=O)(=O)NC3CC3)cc2)nc1 +Cc1cc(-c2ccccc2)n2nc(C(F)(F)F)nc2n1 +COC(=O)CC(C)NC(=O)c1cc2ccc(Cl)cc2[nH]1 +Cc1cc(C(=O)Nc2nc3ccccc3s2)c(C)n1C(C)C +CC(C)c1nc2cc(C(=O)NCc3ccncn3)ccc2o1 +CC(C)(C)NC(=O)C(NC(=O)OCc1ccccc1)c1ccccc1 +CC(C)N(Cc1ccccn1)C(=O)CCC(=O)c1ccc(F)cc1F +CN(CC(O)C1CC1)C(=O)CCc1cccc(Cl)c1 +N#Cc1ccc(NC(=O)c2cccc(OCC(F)F)n2)cc1 +Cn1nncc1CN1CCN(CC(F)(F)F)c2ccccc21 +Fc1ccc(OCc2nnc(SCC(F)(F)F)o2)cc1 +O=C(c1ccc(Cl)c(Cl)c1)N(CCO)C1CCCC1 +Cc1ccc(-c2nc(CCNC(=O)NCc3cccnc3)co2)cc1 +COc1ccc(-c2nc(C)c(C#N)c(SC)n2)cc1 +CCc1nc(NCCN2CCOCC2)c2cnn(C)c2n1 +CCCNC(=O)Cn1cccc1-c1nc(-c2ccc(F)cc2)no1 +O=C(CCCC(=O)c1ccc(F)cc1)NCc1nc2ccccc2[nH]1 +Nc1ncc(S(=O)(=O)N2CC3CCC2C3)cn1 +CC(=O)NC(CC(=O)NCc1noc(C)n1)c1ccc(F)cc1 +N#Cc1nc(-c2ccccc2Br)no1 +Cn1nccc1CNC(=O)c1cccc(CN2CCCC2=O)c1 +CN(C)C(CNS(=O)(=O)c1cccc(Cl)c1)c1cccs1 +Cc1occc1C(=O)NCC(=O)OCc1noc(C2CC2)n1 +Cc1csc(N2CCCC(c3nc4c(C)cccc4[nH]3)C2)n1 +Cc1ccc(O)c(NC(=O)c2[nH]nc(C)c2Br)c1 +CCCNC(=O)N1CCN(CC(=O)N2CCc3ccccc32)CC1 +CC(=O)c1cccc(Oc2ccc3nnnn3n2)c1 +COc1cc2c(cc1C(=O)NCc1ccccc1F)OCCCO2 +O=C(c1csc(C2CCCO2)n1)N1CCc2ccc(Cl)cc2C1 +Cc1c(Cl)cccc1NC(=O)c1cccc(-n2cnnc2)n1 +CNC(=O)Cc1nc2ccccc2n1CC(=O)Nc1ccc(F)cc1 +CC(=O)N1CCN(CC(N)=O)C(c2ccc(C(F)(F)F)cc2)C1 +N#CCOc1cccc(NCc2ccc(O)cc2)c1 +O=C(NCC(O)COCC1CC1)Nc1ccc(Cl)cc1 +CC(C)N(C(=O)COC(=O)c1ccc(C#N)cc1)C(C)C +N#Cc1cccnc1N1CCCN(C(=O)NCC2CC=CCC2)CC1 +CC(C)(C)OC(=O)Cc1cccc(NC(=O)NCc2ncc[nH]2)c1 +N#Cc1ccc(CNC(=O)Nc2ccncc2)cc1 +Cc1ccc(OCc2nnc(NC(=O)Cc3ccccc3)s2)cc1 +COc1ccc(Cl)cc1CNc1cccnc1OC +CN(C)c1nc(NCc2ccccc2Cl)c2cnn(C)c2n1 +CN(C(=O)c1n[nH]c2c1CCC2)C1CCN(C(=O)OC(C)(C)C)CC1 +C=CCOC(=O)c1cc(Br)cc2nc[nH]c12 +COC(=O)C(C)(C)NC(=O)CCOc1ccc(F)cc1 +COCc1cc(C(=O)N(CCC(N)=O)c2ccccc2)ccc1F +Cc1ccn(Cc2c(C#N)c(C)nn2-c2ccccc2)c(=O)c1C#N +CC(C)(C)OC(=O)NCCCNC(=O)c1cc2c([nH]c1=O)CCCC2 +CC(CO)C(C)NC(=O)NCCc1cc(Cl)cc(Cl)c1 +Nc1ccc2c(c1)oc(=O)n2Cc1ccccc1Cl +Cc1ccc(CNC(=O)NCC(=O)Nc2ccccc2Cl)cc1 +CCN(CC)C(=O)CNC(=O)c1oc2c(c1C)C(=O)CC(C)(C)C2 +Cc1noc(C(C)C)c1C(=O)Nc1nc(-c2cccc(O)c2)cs1 +O=C(Nc1cccc(Cl)c1)C1CC(O)=Nc2nncn21 +O=C(NCCC(O)c1ccco1)NCc1cccc2ccccc12 +Cc1nc(N(C)CC(C)C)c2c3c(sc2n1)CCC3 +O=C(CCCc1nnc2ccccn12)Nc1ccc2c(c1)OCCO2 +C=CCNC(=O)c1cccc(S(=O)(=O)NC2CCCC(C)C2)c1 +c1ccc(-c2nc(COc3ccc(-c4nnco4)cc3)no2)cc1 +COC(=O)CN(C(=O)c1ccc(Cn2ccccc2=O)o1)C(C)C +COc1ccc(CCNC(=O)Cc2ccccc2)cc1 +Cc1ccc(S(=O)(=O)C(C)C(=O)N(C)C2CCCCC2)cc1 +COC(=O)CCNC(=O)COc1cc(C)ccc1F +CCOC(=O)c1sc2nccc(OC)c2c1-n1cccc1 +CCCCc1noc(CSc2ccc(C)cn2)n1 +Cc1cccc(C)c1OCCNC(=O)CN1CCOCC1C +Cn1cc(C(=O)Nc2nncs2)c(=O)c2cccc(F)c21 +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)c1C +Cc1cc(CN(C)C(=O)C(c2ccccc2F)N(C)C)ccn1 +CC(Sc1ccccn1)C(=O)NCc1ccccc1F +Cc1cc(C)cc(OC(=O)COCc2nc(C)no2)c1 +O=C1OCC2Cc3ccccc3C(c3ccccc3)=C12 +COc1cc(C)c(C)cc1S(=O)(=O)NCC(O)Cc1ccccc1 +COC(=O)NCC(=O)N1CC(Oc2ccccc2Cl)C1 +CC(C)c1nc(CC(=O)Nc2cccnc2N2CCCC2)cs1 +N#Cc1cccc(Cn2c(=O)oc3cc(CO)ccc32)c1 +O=c1[nH]c(C2CCOC2)nc2cc(C(F)(F)F)ccc12 +COc1ccccc1OCC(CC#N)N1CCOCC1 +Cc1cc(C)c(S(=O)(=O)n2cccn2)cc1Br +CC(=O)Nc1ccc(OCC(O)Cn2cnc3ccccc32)cc1 +CC(NC(=O)c1ccco1)c1ccccc1OC(F)F +CN(Cc1ccc(Cl)cc1)C(=O)c1cccc2[nH]ccc12 +Cc1csc(N2CCCN(C(=O)NCC(=O)N(C)C)CC2)n1 +NC(=O)Cn1nc(-c2ccc(C(F)(F)F)cc2)c2c1CCNC2 +CN(Cc1ccco1)C(=O)Nc1ccc2c(c1)n(C)c(=O)n2C +O=S(=O)(CCOc1ccccc1)NCc1cccs1 +CC(C(=O)NCCc1ccccn1)c1ccsc1 +C=C(C)Cn1c(-c2ccccc2OC)ccc(C#N)c1=O +Nc1nc2cc(Br)ccc2n1CC1CCCOC1 +COC(=O)c1sc(NC(=O)CCc2cccs2)nc1C +COc1ccc(N(Cc2ccco2)C(=O)Cc2cnn(C)c2)cc1F +COCCCNC(=O)N1CCCC1c1cc(C)no1 +O=C(CNc1cnc2sccn2c1=O)N1CCOCC1 +C=CCn1c(C)cc(C(=O)CN(C)Cc2cccc(F)c2)c1C +CC(=O)Nc1cc(NC(=O)Nc2ccc3c(c2)CC(=O)N3)ccc1F +Cc1ccc(NC(=O)c2ccc(NS(C)(=O)=O)c(C)c2)c(C)c1 +COc1nn(C)cc1-c1nnc(SCC(=O)c2ccccc2)n1C +Cc1cc(C)c(C(=O)NCc2nccn2Cc2ccccc2)c(=O)[nH]1 +Cc1cc(C(=O)N(CCO)C2CCCCC2)no1 +O=C(c1ccc2c(c1)OCO2)N1CCN(Cc2cccs2)CC1 +COCc1cc(NCC(F)(F)F)n2nccc2n1 +CCc1nnc(Nc2cc(C)nc(C3CCN(C(=O)CO)C3)n2)s1 +CCNC(=O)C1CCCN(c2nn3c(=O)cc(C)nc3s2)C1 +CCCCn1c(S(=O)(=O)Cc2cccc(F)c2)nc(C)c1C +Cc1ccc(Br)cc1-c1ccc(N)cn1 +NS(=O)(=O)N1CCN(CC(O)c2ccc(F)c(F)c2)CC1 +CCN1CC(C(=O)Nc2sc3c(c2C(N)=O)CCCCC3)CC1=O +CC(O)CNC(=O)c1ccc(CSc2nc3ccccc3[nH]2)cc1 +CC(Sc1ncn[nH]1)C(=O)NCc1ccc(Cl)cc1 +CCc1cc(C(=O)NCCCN2CCOCC2)no1 +C#CCn1c(CNC(=O)c2cccc(OC)c2)nc2ccccc21 +O=C(NCc1nc(-c2ccc(F)cc2)n[nH]1)c1ccc2[nH]nnc2c1 +Cc1noc(C)c1CN(C)C(=O)NCc1cccc(F)c1 +COc1ccsc1C(=O)NC(C#N)c1ccc(Cl)cc1 +CCn1c(C)c(C(=O)CSc2ncccc2C#N)c2ccccc21 +CC(=O)N1CCc2ccccc2C1CC(=O)N(C1CCCC1)C1CC1 +Cc1nn(C)cc1C(=O)NC(Cc1ccccc1)C1CC1 +CCOC(=O)Nc1ccc(NC(=O)NCc2csc(CC)n2)cc1 +CCOc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1Cl +COCCNC(=O)Nc1ccc(OC)c(N2CCCC2=O)c1 +CC(=O)Nc1cccc(C(=O)NC2CCCCC2OCCC(C)C)c1 +CC1(C(=O)NCC(=O)N2CCCCC2)Sc2ccccc2NC1=O +Cc1cc(C)c(NC(=O)C(C)n2sc3ccccc3c2=O)c(C)c1 +Cc1ccc(-c2cn(CC(=O)NC(C)C)c(=O)o2)cc1 +O=C(COc1ccc(Cl)cc1)NCc1nnnn1-c1ccccc1 +CN(CCC#N)C(=O)c1cnc(C2CCCO2)s1 +Cc1cccc(OCc2nc(C(=O)NCC3CCCO3)cs2)c1C +Cc1cc(NC(=O)Cc2ccc(OCc3c(C)noc3C)cc2)no1 +Nc1cccc(NS(=O)(=O)CC2CCCCC2)c1 +Cc1ccc(-c2csc(NC(=O)Cn3ccccc3=O)n2)s1 +CCCCCNC(=O)C1CCN(C(=O)c2nc3ccccc3[nH]2)CC1 +CC(C)c1nc(-c2cc(C(=O)NCC3CC3)c3ccccn23)cs1 +OC(COCc1ccco1)Cn1nnnc1-c1ccccn1 +COc1cc(NC(=O)NCC2(O)CCCC2)cc(OC)c1OC +CC(C)c1ncc(Cl)c(C(=O)N(C)c2cccnc2N(C)C)n1 +CC(C)NC(=O)c1nccn1-c1cccc(C#N)c1 +Cc1ccccc1-n1nccc1NC(=O)CCCn1cccn1 +CCN(CCNC(=O)NCC(=O)N1CCCC1)c1ccccc1C +O=C(NCc1ccnc(OC2CCC2)c1)NCc1ccccn1 +Cc1ccsc1C(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +CCS(=O)(=O)c1ccc(CCC(C)(C)O)cc1 +Cn1cnc(CNC(=O)Nc2ccccc2Oc2ccccc2)n1 +CCCNc1nnc(-c2csc(COC)n2)s1 +COc1cc2nc(C#N)n(C(C)(C)C)c2cc1OC +CCN(Cc1ccccc1C)C(=O)C1CCC(=O)N1 +CC(=O)Nc1ccc(C2NC(=O)c3ccc(Cl)cc3N2)cc1 +Fc1cccc(F)c1Nc1nc2cc3c(cc2[nH]1)OCCO3 +Cc1cc(C)n(CCCC(=O)Nc2cccc(N)c2C)n1 +COc1cc(-c2cc(=O)[nH]c(=O)[nH]2)c(OC)cc1C +C=CCN1CCN(C(=O)Cc2ccccc2OC)CC1 +COc1ccc(OCc2nc3c4c(C)c(C)sc4ncn3n2)cc1 +CN(Cc1ccco1)S(=O)(=O)c1cc(N)ccc1Cl +Cc1cc(C)c(NC(=O)c2cnc3ccccc3n2)c(C)c1 +COC(=O)c1ccc(NC(=O)C2(O)CCCC2)cc1 +CC(=O)c1cccc(OC(C)C(=O)Nc2nc(C)c(C)s2)c1 +Cn1c(=O)n(CC(=O)Nc2ccccc2O)c2ccccc21 +O=C1NCCCCC1n1cnc2sccc2c1=O +COC(=O)CN(c1ccc(C)cc1)S(C)(=O)=O +O=C(NC1CS(=O)(=O)c2ccccc21)c1ccc2c(c1)CCCC2 +CCCc1nnc(NC(=O)C2CCN(c3ccccc3F)CC2)s1 +COc1cc(C)c(S(=O)(=O)N(C)CCO)cc1OC +CC(C)OC(=O)CSc1nnc(C2CCCCC2)n1N +C=CCNC(=O)C(C)OC(=O)c1ccc2c(c1)OCCO2 +CCCCc1noc(C2CCCN(C(=O)c3ccc(C)o3)C2)n1 +COc1ccc(C(=O)Nc2cc(NC(C)=O)ccc2F)nn1 +Cc1cc(Br)cnc1NCC(C)(O)CN1CCOCC1 +COc1ncccc1CNC(=O)NC(C)CCc1ccccc1 +COc1ccc(C#CCNC(=O)CC(C)(C)C)cc1 +CNc1nc(-c2csc(N3CCCC(C)C3)n2)cs1 +COc1ccc2cc(C(=O)N(Cc3cccnc3)C3CC3)[nH]c2c1 +CN(Cc1cnn(C)c1)C(=O)COc1ccc2oc3ccccc3c2c1 +CN(C)S(=O)(=O)CCC(=O)NC1CCc2c(Cl)cccc21 +O=C1CCc2cc(OCC(=O)N3CCNCC3)ccc2N1 +CCOC(=O)CCn1nc(C)c2c1CCCC2CC#N +Cc1cnc(-c2cccc(NC(=O)NC(CCO)C3CC3)c2)o1 +Cc1nc(C)c(CNC(=O)c2cccc(N3CCCC3=O)c2)s1 +COC(=O)c1cccc2nc(-c3cccc(F)c3)nn12 +CCC(O)Cn1nc(C)nc1CCc1ccc(C)cc1 +CC(=O)Nc1cc2nn(-c3ccccc3)nc2cc1Cl +Cc1ccccc1-n1c(C)nnc1SCC(=O)N1CCCC1 +CCCc1noc(CSc2nc3ccccc3n2CCC#N)n1 +Cc1ncc(-c2ccc(S(=O)(=O)N3CCCCC3)cc2)o1 +O=C(NC1CC1)C1CCCN1C(=O)Cc1ccc(F)cc1 +CCc1nc(NC(=O)N(C)Cc2cccc(-n3cccn3)c2)nn1C +Cc1noc(CCCC(=O)NCC2(c3ccc(F)cc3)CCCC2)n1 +O=C(CCCOc1ccccc1)NCc1ccc(F)cc1 +Cc1n[nH]cc1NC(=O)c1ccc(=O)n(CCOc2ccccc2)n1 +CC1CN(CC(=O)N2CCCC2)c2ccccc2N1 +Fc1ccc(CSc2ncnc3c2ncn3C2CCCO2)cc1 +COc1cc(COc2ccc(Cl)cc2N)cc(OC)c1OC +Cc1cccc(C(=O)N2CCC(C(=O)NCc3ccccc3)CC2)c1 +CCN(CC(C)C#N)C(=O)c1ccc2ncsc2c1 +C=CCN(C(C)=O)c1nc(N)n(-c2ccccc2)n1 +COCc1cccc(NC(C)C(=O)N2CCC(C)CC2)c1 +O=C(CNC(=O)c1ccsc1)NCc1ccc(O)cc1 +CC(C)(C)c1nnc(NCc2nncn2-c2ccccc2)s1 +CC(=O)N1CCN(C(=O)CCc2cnn(-c3ccccc3)c2)CC1 +Cc1ccc2c(c1)N(CC(=O)NCCc1ccccc1)C(=O)CO2 +CCC(C)(C)c1ccc(OC(=O)c2cc(C(N)=O)cn2C)cc1 +C=CCCC(=O)N1CCC(c2nn(C)c(=O)n2C2CC2)CC1 +C=C(C)COc1ccc2nc3n(c(=O)c2c1)CCC3 +CCCC(C)(CO)NC(=O)NCc1ccc(O)c(F)c1 +COC(=O)C(C)Sc1nnc(C2COc3ccccc3O2)n1C +COC1CCN(C(=O)Cc2csc(N3CCCC3=O)n2)CC1 +O=C(c1ccc(-c2ccccc2)cc1)N1Cc2nn3nccnc3c2C1 +CC(C)n1ncc2cc(C(=O)Nc3cc[nH]n3)cnc21 +N#CC(c1ccccc1)N1CCN(C(=O)c2ccoc2)CC1 +CCCCOC(=O)CNC(=O)c1cc2c([nH]c1=O)CCCC2 +COCCn1c(C)nc2nnc3ccc(C(=O)NC(C)C)cc3c21 +Cc1cccc(CC(=O)Nc2ccccc2CO)c1 +Cc1ccc2ncc(C(=O)NCC3CCC(C)CC3)c(=O)n2c1 +O=C(Cc1ccc(Cl)cc1)N1CCCCC1CO +COc1ccccc1N1CCN(C(=O)C(C)n2cncn2)CC1 +CCn1ccc2ccc(NC(=O)c3ccnc4c(C(N)=O)cnn34)cc21 +Cc1ccc(NC(=O)COc2cccc(F)c2)cc1F +CC(C)N1CCCC2(CCN(C(=O)Cc3cccc(Cl)c3)C2)C1=O +Cc1ccc(C)c(NC(=O)Nc2cccc(N3CCNC3=O)c2)c1 +CCCc1nc(CNc2ccn(-c3ncccc3Cl)n2)no1 +Cc1cccnc1NC(=O)c1cc2c(nc1N)CCC(C)C2 +CCOC(=O)c1ccn(-c2ccccc2C(F)(F)F)n1 +CCOC(=O)CC(C#N)c1ccc(OC)c(OC)c1 +COc1ccc(SCC(=O)Nc2ccc(F)cc2F)cc1 +COc1ccc(CCc2nc(-c3nonc3N)no2)cc1 +O=S(=O)(c1ccc(C2CCCCC2)cc1)N1CCC(O)CC1 +Cc1ccc(CNC(=O)CCn2nc(C)c(Cl)c2C)o1 +Cc1ccc(CC(=O)Nc2ccc(F)cc2Br)cn1 +COc1cccc(CC(=O)Nc2ccc(OC)nc2)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)CCC(C)(C)C +O=c1ccnc(SCc2cccc(C(F)(F)F)c2)[nH]1 +O=C(NCC1CCOCC1)C1CC(=O)N(c2n[nH]c3ccccc23)C1 +CCOC(=O)C1(C(C)C)CCCN(C(=O)OC(C)(C)C)C1 +COCCN1C(=O)CCC12CCCN(S(C)(=O)=O)CC2 +Cc1nc(C)c(CNCc2c(F)cccc2Cl)s1 +N#CC(NC(=O)c1cccc(Br)c1)c1ccccc1F +COC(=O)Nc1ccc(NC(=O)NC2CCc3c(O)cccc32)cc1 +Cn1cc(Br)cc1C(=O)NCc1nc2ccccc2n1C +COc1ccc(S(=O)(=O)NCCC#N)cc1OC +Cc1ccc(C(=O)C(C)C)cc1S(=O)(=O)NC1CC1 +C#CCNC(=O)CN1C(=O)COc2ccc(Cl)cc21 +FC(F)(F)COc1ccc(NCc2ccco2)cn1 +Cc1nnc(COc2ccc3ccc(O)cc3c2)o1 +CC(CC(=O)Oc1cccc(S(C)(=O)=O)c1)c1ccc(F)cc1 +CC(O)CNc1ccc(NC(=O)c2ccc(Cl)c(Cl)c2)cn1 +C=CCNC(=O)c1ccnc(OCc2ccccc2)c1 +COc1ccc(OC)c(-c2[nH]c3nc4cc(N)ccc4n3c2C)c1 +CCc1ccc(C2COCCN2Cc2cccnc2C)o1 +Cc1c(NCc2ccc(C(=O)N(C)C)[nH]2)cnn1-c1ccccc1F +O=C(NCc1ccccn1)NC(c1ccccc1)c1cccc(F)c1 +Cc1nc(C2CCCN(Cc3nc4ccccc4n3C)C2)cc(=O)[nH]1 +COCCCN1CC2(CCCN(c3nc(C)cc(C)n3)C2)CCC1=O +COC(=O)Nc1cccc(NC(C)c2ccc(S(C)=O)cc2)c1 +CC(c1ccccc1Cl)N(C(=O)C1CCC(C(N)=O)CC1)C1CC1 +Cc1ccc(CNC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)cc1 +CCOC(=O)N1CCC(Nc2cn[nH]c(=O)n2)CC1 +CCCCNC(=O)N1CCc2ccc(OC)cc2C1 +CNc1nn2c(=O)c(Cc3ccccc3Cl)nnc2s1 +COc1cccc(C2CCCN2C(=O)c2cc3ccccc3oc2=O)c1 +O=c1ccc(C2NCCc3cccc(OC(F)F)c32)c[nH]1 +COc1cc(C)ccc1NC(=O)CCCNC(=O)c1ccco1 +O=c1[nH]c(NCc2ccc(Cn3cncn3)cc2)nc2ccccc12 +CC1CN(C2CCN(C(=O)NC(C)C(C)C)CC2)CCO1 +Cn1ncc2c1C(COCC1CC1)N(C(=O)c1cscn1)CC2 +CC(C)C(=O)Nc1ccc(C(=O)N2CCc3ncccc3C2)cc1 +O=C(NCc1ccc(F)cc1)c1cc(-c2ccco2)on1 +CCc1c(C)sc2[nH]c(-c3cccc(OCCO)n3)nc(=O)c12 +COc1ccc(Cc2nc(CCO)cs2)cc1Cl +N#Cc1ccc(NCc2ccccc2OC(F)F)nc1 +CCCNC(=O)Nc1cccc(-n2nnnc2C)c1 +CNc1nc(-c2cnn(-c3ccc(C)c(C)c3)c2C)cs1 +CCCNC(=O)CCN(C(=O)c1ccoc1C)C1CC1 +CCOc1ccc(C(C)C)cc1S(=O)(=O)n1ccnc1 +CCN(CC)C(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +COc1cccc(C(=O)NCc2ccc(-c3cccnc3)cc2)c1F +Cc1ccn2c(=O)cc(COc3ccc4ccc(=O)oc4c3)nc2c1 +COc1cccc(CC2CN(CC(=O)Nc3cc(C)on3)CCO2)c1 +Cc1ccc(CC(=O)NCc2ccc(S(N)(=O)=O)s2)cc1 +COc1ccc(C(=O)NCc2cccc(O)c2)c(OC)c1 +Cc1nn(C)c(C)c1NC(=O)CNc1ccc2ccccc2c1 +C#CCNC(=O)Cn1nc(C)c2ccccc2c1=O +CCCn1c(-c2ccc(OC)c(OC)c2)ccc(CO)c1=O +Cc1cc2c(=O)n(CC(=O)Nc3c(F)cccc3F)cnc2s1 +c1ccc(C2NC(c3cccnc3)NC2c2ccccc2)cc1 +Cc1cc(=O)oc2cc(OCCOc3ccccn3)ccc12 +N#Cc1cnn2c3c(cnc12)C(=O)N1CCc2ccccc2C1C3 +O=C(NCC1CCCO1)c1ccc(-c2ccccc2F)o1 +NC(=O)C(NCC(F)(F)F)c1ccc(Cl)c(Cl)c1 +NC(=O)Cn1c(CO)cnc1SCC(=O)Nc1ccccc1F +O=C(Nc1cccnc1-n1cccn1)c1ccc2ccccc2n1 +O=C(c1cccn2ccnc12)N1CCCN(c2cccnn2)CC1 +Cc1cccc(OCc2nc(-c3ccc(N)cc3)cs2)c1 +CSc1nn2ccccc2c1-c1ccc(N)cc1 +COC(=O)C(c1c(Cl)cccc1Cl)N(C)C +CC(=O)Nc1cccc(C(=O)OCC(=O)N2C(C)CCCC2C)c1 +CCCC(NC(N)=O)C(=O)N(C)c1cc(C)cc(C)c1 +COc1ccc2c3c(ccc2c1)CCNC3c1nccs1 +Cc1cc(C)c(C(=O)Cn2nc(C)c(C)c(C#N)c2=O)cc1C +Cc1ccc(F)cc1NC(=O)N1CCCC(C)C1 +COCc1c(Cl)cccc1NC(=O)c1cnc2ccc(C)cn12 +CCCc1nc(C(=O)NCc2cnc(SC)n2C)cs1 +Cc1noc(C)c1CN1CCN(C(=O)Cc2ccccc2Cl)CC1 +N#CC1(C(=O)Nc2ccc(OC(F)F)c(F)c2)CCCC1 +CC(NS(=O)(=O)c1ccccc1F)C(=O)NC(C)(C)C +O=C(CCCn1cccn1)N1CC=C(c2c[nH]c3ccccc23)CC1 +O=C(NCCc1cnc(-c2ccccc2)[nH]1)c1ccco1 +COc1ccccc1CNC(=O)CCc1c(C)nc(SC)nc1C +OCC=CCOc1ncc(C(F)(F)F)cc1Cl +Cc1cccc(OC(C)C(=O)N2CC(C)OC(C)C2)c1 +CCCCn1nnnc1COC(=O)c1ccc2c(c1)OCO2 +Cc1ccc(N)cc1NC(=O)CSc1nc(N)cc(N)n1 +COc1ccc(F)cc1-c1c(N)n[nH]c1-c1cccs1 +CC(C)CCN1C(=O)C2(OCCO2)c2cc(Cl)ccc21 +Cn1cnc(CNC(=O)C(c2ccccc2)N2CCCCC2=O)n1 +Cc1cc(C)c(CNC(=O)c2ccc(-c3ccc(F)cc3)o2)c(=O)[nH]1 +O=C(c1ccncc1)N1CCC(c2nc(-c3ccncc3)cc(=O)[nH]2)C1 +CC(C)c1nc(C2CCN(C(=O)c3ccco3)CC2)no1 +Cc1cnc(NC(=O)c2cn(C)nc2-c2coc3ccccc23)s1 +COC(=O)NCCC(=O)Nc1ccc(Cl)c(Br)c1 +COCCOCC(=O)NC(C)c1cc(C)sc1C +CCCCOc1ccc(C(=O)N(C)C)cc1OCC +COC(C)c1nc(C)c(C(=O)OC2CCCC2n2cccn2)s1 +Cc1ccc(S(=O)(=O)NCc2c(-c3ccccc3)noc2C)cc1 +COc1ncnc2c1CN(Cc1cnc(C)s1)CC2 +CCCc1cc(C(=O)OCc2nc(-c3ccccc3)no2)[nH]n1 +COC(=O)c1sc(NC(=O)c2ccc(C(C)=O)cc2)nc1C1CC1 +O=c1ccn(Cc2ccn(-c3ccccc3)n2)c2ccsc12 +Cc1ccc(C)c(NC(=O)Cn2cnc3onc(C)c3c2=O)c1 +Cc1ccncc1-c1nc(-c2cccc(N)c2)cs1 +OC1CCN(c2cc(-c3ccccn3)nc(-c3cccnc3)n2)CC1 +COc1cccc(N2C(=O)c3cccnc3C2O)c1 +Cc1cccc(CS(=O)(=O)NCc2nn(C)c3c2CCCC3)c1 +Cn1c(=O)c2cc(NC(=O)COc3ccccc3)cnc2n(C)c1=O +CCN1CC(C(=O)Nc2ccc(CN3CCCC3=O)cc2)CC1=O +COc1ccc(C)cc1-c1c(C)sc(C#N)c1NC(C)=O +CC(C)c1nc(CC(=O)N2CCC(C(N)=O)c3ccccc32)cs1 +COc1ccc(-c2nc(C)c(C(=O)NC(C)(C)C)s2)cc1OC +CCCN1C(=O)C(NC(=O)C2CC2)(C(F)(F)F)C(C(=O)OC)=C1C +CCOc1ccccc1Nc1ccc2nnnn2n1 +COc1ccc(C)cc1N1CCC(C(=O)NCC2CC2)C1=O +COC(=O)C(NC(=O)c1nc(-c2ccccc2)oc1C1CC1)C(C)C +CCN1CCc2nc(NC(=O)c3ccccc3)sc2C1 +O=C(OCc1ccccc1Cl)c1cnc(C2CCCO2)s1 +Cc1nn(C)c2ncc(NC(=O)NC3CCCC3)cc12 +Nc1ncc(S(=O)(=O)NC2CCCC2)cc1Cl +CCc1csc(CNC(=O)c2coc3c2C(=O)CCC3)n1 +C=CCNC(=O)CCNS(=O)(=O)c1ccc2c(c1)CCCC2 +CCn1c(C)cc(C(=O)Nc2ccc(C(=O)OC)cc2)c1C +CCC1CN(C(=O)c2ccc(NC(=O)c3cccs3)cc2)CCO1 +Cc1oc(-c2ccsc2)nc1CC(=O)NCC(=O)OC(C)(C)C +CC(C)n1ncc2cc(NC(=O)c3ccccc3O)cnc21 +CC(C)CNC(=O)c1cccc(C#CCCCCO)c1 +CC(=O)N1CCc2cc(C(=O)Nc3ccc(C#N)cc3)ccc21 +COc1ccccc1NC(=O)c1cc(-c2cccs2)on1 +COc1ccc2c(c1)nc(CO)n2Cc1cccc(C#N)c1 +C=CCOc1ccc(CN2CCOC(C)(C)C2)cc1OC +C=CCNC(=O)N1CCN(Cc2csc(CC)n2)CC1 +COc1ccc(Cl)cc1CCNC(=O)N(C)CC1CCOC1 +COC(=O)C1CCCCCC1NC(=O)CC1OCCc2ccccc21 +CCN1CC(C(=O)N2CCCC(CNC(C)=O)C2)CC1=O +CC(C)c1nc(C#N)c(-c2cc(C(C)(C)C)[nH]n2)[nH]1 +COc1ccc2c(c1)nc(-c1ccc(F)cc1)n2CCC#N +CCNC(=O)c1cccc(C)c1OCc1nnc(SC)s1 +C#CCN1CCC(C(=O)Nc2ccc(F)c(F)c2F)CC1 +Cc1nn(-c2ccc(F)cc2)c(C)c1CC(=O)Oc1ccccc1 +COc1ccc2c(ccn2CCC(=O)Nc2ccc(C(N)=O)cc2)c1 +COc1ccc(C(=O)NC2CCN(S(C)(=O)=O)CC2)cc1 +C=CCSc1nnnn1Cc1ccc(OC)cc1 +O=C(c1ccc[nH]c1=O)N1CCOC2CCCCC21 +CCCOc1cccc(C(=O)C(C#N)c2nc3ccccc3[nH]2)c1 +COCC(NC(=O)C1CC1c1ccccc1C)C(N)=O +Cn1nccc1CNC(=O)CCc1nc(-c2ccncc2)no1 +CCOC(=O)CNC(=O)C(N)c1ccccc1F +Cc1ccc(C(=O)N2CCN(C(=O)CCOC(C)C)CC2)cc1F +CN(Cc1cccs1)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +Cc1cc(S(C)(=O)=O)ccc1NC(=O)C1CCCc2ccccc21 +CC(C)Cc1noc(Cc2cccc(OCC#N)c2)n1 +COc1cc(NC(=O)C(C)C)c(C(N)=O)cc1OC +Cn1cccc1C(=O)Oc1ccc(N2CCOC2=O)cc1 +CS(=O)(=O)c1ccc(CC(=O)NCC2CCCO2)cc1 +CC(C)COC(C)c1noc(CNc2c(F)cc(F)cc2F)n1 +CCNC(=O)N(Cc1ccncc1)CC1CCCO1 +CC(NC(C(N)=O)c1ccc(F)cc1)c1ccc(Cl)cc1 +Cc1ccc(N2CCC(NC(=O)Cc3cccs3)C2=O)cc1C +CC(O)(CNC(=O)C1CCOCC1)c1ccc(F)cc1F +Cc1noc(C2CN(S(=O)(=O)c3cccc(F)c3)C2)n1 +Cc1cc(Cl)ccc1NC(=O)Cc1cccc(N)c1 +COCCn1ccc(NC(=O)c2c[nH]nc2-c2ccccc2Cl)n1 +COC1COC2(CCCCO2)C(OCc2ccccc2)C1 +COC(CNS(=O)(=O)c1cnn(C)c1)c1ccccc1C +COCCOc1ccc(C(=O)CC(C)(C)C)cc1 +CCOc1ncccc1C(=O)Nc1cccc(C(=O)N(C)C)c1 +C=CCc1cc(CNC(=O)Nc2cccnc2)cc(OC)c1OC +Cc1nn(C)c(C)c1C1CCCN1C(=O)c1cnccn1 +COc1ccccc1C(=O)NCCC(=O)NCc1ccccc1 +CCOc1cccc(CNc2ncccc2Cl)c1 +Cc1cc(C)n2ncc(C(=O)Nc3cccnc3N3CCCC3)c2n1 +Cc1ccc(CCC(=O)Nc2cn(C)c(=O)cc2C)c(C)c1 +Cn1cnc(CNC(=O)NCCc2c[nH]c3cc(F)ccc23)n1 +Cc1ccc(-c2nc(C)c3c(n2)N(Cc2ccco2)C(=O)C3)cc1 +COCCOc1ccc(NC(=O)N2CC(CO)OCC2C)cn1 +C=CCNC(=O)c1nnsc1-c1ccc(C)cc1 +COCC12CCOC1CCN(Cc1sccc1C)C2 +CCC(CC)NC(=O)c1ccc(N(C)S(C)(=O)=O)cc1Cl +CCCC(=O)NC(C)c1cccc(N2CCOC2=O)c1 +Cc1ccc2nc3c(cc(C(=O)Nc4cccnc4)n3C)c(=O)n2c1 +CC(C)CC(C)OCCC(=O)N1CCCS1(=O)=O +CCNC(=O)c1ccc(CNC(=O)Nc2ccc(C)c(Cl)c2)cc1 +COc1ccc(CNC(=O)NCc2cccnc2)cc1OC +CC1CN(S(=O)(=O)N(C)CCC#N)CC(c2ccccc2)O1 +CC(=O)Nc1ccc(NC(=O)C(C)Nc2ccc(C)cc2)cc1 +COCCNC(=O)C1COc2ccc(F)cc2C1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)OCC(=O)N1CCCC1 +CC(C)(C)c1cn2nc(NCCCCN3CCOCC3)sc2n1 +CCCc1nnsc1C1NCCc2ccc(O)c(F)c21 +CC(C)C(NC(=O)C1CCCCC1)C(=O)N1CCC(C(N)=O)CC1 +Cc1cc(Cl)ccc1NC(=O)Cn1cc(N)cn1 +COc1cc(C(=O)Nc2cc(Cl)ccc2C#N)on1 +CCCCCCOc1cccc(S(C)(=O)=O)c1 +Cc1ccc(NC(=O)NC2c3ccccc3CC2O)cc1 +Cc1cccc(NC(=O)N2CCN(Cc3cccc(O)c3)CC2)c1 +O=C(CNC(=O)c1cnc(C2CCCO2)s1)Nc1ccc(F)cc1 +Cc1cccc(C(C)C)c1NC(=O)NCCCN1CCOCC1 +COC(=O)c1cccc(NC(=O)c2cccc(C)c2)c1 +CSc1cccc(NC2OC(=O)c3ccccc32)c1 +N#Cc1ccc(Cn2nnn(-c3ccccc3Cl)c2=O)c(F)c1 +O=C(Nc1ncn(Cc2cccc(F)c2)n1)c1ccccc1Cl +NC(=O)c1c[nH]c(C(=O)N2CCCCC2CCc2ccccc2)c1 +Nc1cc(=O)[nH]c(SCC(=O)Nc2cc(F)ccc2F)n1 +CCOCCC(=O)NC(c1ccccc1)c1ccccc1 +CC(C)CN(CC(C)(C)C)C(=O)c1cnc(C2CCCO2)s1 +CCCc1c(C(=O)Nc2nncs2)cnn1Cc1ccccc1 +COc1ccc(CCC(=O)NCc2nc(C)no2)cc1 +CCCc1ccc(-c2nc3sc(C)nn3c2C#N)cc1 +CC(NC(=O)C1CCN(c2nc3ccccc3o2)CC1)C1CCCO1 +CCN(CCC#N)C(=O)CSc1ccc2ccccc2c1 +CC(Cn1cncn1)NS(=O)(=O)c1ccc2c(c1)N(C)CCC2 +Cc1c(C(=O)OCCOc2ccccc2)sc2nc[nH]c(=O)c12 +CC(C)C1(C)CC(=O)c2cc(Cl)cc(N)c2O1 +Cc1cccc(C2NC(=O)NC3=C2C(=O)N(CCO)C3)c1 +CN1C(=O)c2cc(NS(C)(=O)=O)ccc2Oc2ccccc21 +N#CCn1cnc2c(cnn2-c2ccc(F)cc2)c1=O +CCNC(=O)c1ccc(NC(=O)N(C)CCCOC)c(C)c1 +O=C(NCCNc1cccc(Br)c1)c1csnn1 +O=C(COC(=O)Cn1nnc2ccccc21)NC1CCCCCC1 +CC1CCCC(CNC(=O)N(C)CCc2ccccn2)C1 +CNC(=O)c1cc(NC(=O)NCCCOC)ccc1Cl +O=C(Nc1cccnc1)N(Cc1ccc2c(c1)OCO2)C1CCCC1 +Cc1ccc(S(=O)(=O)N(CCC#N)Cc2ccccn2)c(C)c1 +CCCn1c(C)nnc1Cn1nc(C(=O)NC)c2ccccc2c1=O +N#Cc1ccc(NCCC(=O)c2cc(F)ccc2F)cc1 +COc1cccc(C(=O)OC(C)C(=O)Nc2ccc(C(C)=O)cc2)c1 +COCCOc1cccc(NCC(=O)N2CCc3ccccc3C2)c1 +CCCOc1ccc(-c2ncc(C(N)=O)c(N)n2)cc1Cl +COc1ccc(C(O)CNc2cc(C(N)=O)c3ccccc3n2)cc1 +CNC(=O)C1CCCCN1C(=O)c1cnn(-c2ccccc2)c1 +OCCCCCn1cc(-c2cc(F)ccc2-n2cccn2)nn1 +Cc1nc(OCC(=O)N2CCCC2)cc(-n2cccn2)n1 +CCC(=O)N1CCCc2cc(NC(=O)c3ccco3)ccc21 +COc1ccc(C(=O)OCC(=O)Nc2cc(C)cc(C)c2)cc1OC +Cn1nnc(NC(=O)c2ccc(Br)cc2)n1 +COCCNC(=O)c1cc2c(s1)N(C)CCC2 +CC1CCCCN1C(=O)c1cc(-c2ccc(F)cc2)no1 +COc1cccc2c1N(CCCNS(C)(=O)=O)CCC2 +CC(C)CC(NS(C)(=O)=O)C(=O)NC(C)CO +CC(OC(=O)c1ccc(-c2ccc(F)cc2)o1)C(N)=O +COC(=O)c1cccc(NC(=O)C2CC(=O)N(C)C2)c1 +Cc1ccc(CN2CCC3C2CCC(=O)N3CC(=O)N(C)C)s1 +Cc1cc(NC(=O)NCc2c(C)nn(-c3ccccc3)c2C)no1 +Cc1nnc(C(C)Sc2nnc(COc3ccccc3)n2N)o1 +CNc1c(N)n(CCc2ccccc2)c(=O)[nH]c1=O +O=C(Cn1ccc(=O)c2cc(Cl)ccc21)Nc1ccccn1 +Cc1cc(Oc2ccc(C#N)cc2)ccc1NC(=O)NCCO +C#CCOc1ccccc1CNC(=O)Nc1ccc(=O)n(CCC)c1 +CCCCn1c(SCC(=O)Nc2c(C)cc(C)cc2C)n[nH]c1=O +CCCCc1cc(NC(=O)Cc2cccc(F)c2)[nH]n1 +CC(NC(=O)Nc1nccs1)c1ccc2c(c1)OCCCO2 +CCN1CC(C(=O)N2CCC(Cn3cc(C)cn3)CC2)CC1=O +COc1ccc(S(=O)(=O)Nc2cccc(N)c2)cc1Cl +CC(C)(C)c1noc(CN2C(=O)c3ccccc3CS2(=O)=O)n1 +Cc1cc(NC(=O)C2CCN(c3ccc(C#N)cn3)CC2)n(C)n1 +COc1ccc(C(O)CNc2ccc(C)cc2)cc1OC +CCc1nc(C)cn1S(=O)(=O)c1ccc2c(c1)OCCO2 +C=CCNC(=O)N1CCN(c2ccc(Cl)cc2)CC1 +Cn1cc(NC(=O)C2CCN(c3ccc(Cl)cn3)CC2)cn1 +NC(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1 +CCC(=O)Nc1ccc(S(=O)(=O)C2CCCC2)cc1 +COc1ccc(-c2csc(NC(=O)c3ccnn3C)n2)cc1OC +CC(C)C(CNC(=O)N(C)Cc1cccc(C#N)c1)N1CCOCC1 +CC1CCN(C(=O)c2nn(C)c(=O)c3ccccc23)CC1 +CC1C(=O)N(CCCC(N)=O)c2cc(N)ccc2N1C +COc1cccc(C(=O)Nc2ccc(-n3ccnc3)c(F)c2)c1F +COCCOC(=O)c1cc(N)c(Cl)c(Cl)c1 +CC(NC(=O)c1ccccc1N1CCOCC1)c1ccncc1 +NC(=O)C1CCCN(C(=O)CCc2ncc(-c3ccc(F)cc3)o2)C1 +CC1CCCN(C(=O)CCNC(=O)OC(C)(C)C)C1 +CC(c1cccc(O)c1)N(C)C(=O)Nc1ccc2c(c1)COC2 +Cc1nnnn1-c1cccc(OCc2nc(CCC(C)C)no2)c1 +CNC(=O)COc1cc(C(=O)NC2CCCCC2)ccc1N +O=C1CC(c2ccc(O)cc2)c2cnn(-c3ccccc3)c2N1 +Cc1sc(NC(=O)COC(=O)c2ccc(F)cc2)c(C#N)c1C +C=C(C)CN(CC)C(=O)COc1ccc(C#N)cc1 +CCN(CCC#N)C(=O)CNc1ccc(Cl)c(C(=O)N(C)C)c1 +Cc1cccc2c(NC3CCCN(C(N)=O)C3)ncnc12 +Cc1cc2c(cc1C)NC1(CCC(C)CC1)C(=O)N2 +Cc1ccc(C(=O)OCc2nc3ccccc3s2)o1 +CC(C)C(C)(C#N)NC(=O)COC(=O)c1cc2ccccc2s1 +NC(=O)c1ccnc(-c2ccc(Cl)c(Cl)c2)c1 +O=C(Nc1nnc(-c2ccsc2)o1)c1c(F)cccc1Cl +O=C(CCc1ccsc1)Nc1nc(CN2CCOCC2)cs1 +CC(=O)NCCCNC(=O)c1ccccc1CC#N +CCNC(=O)CSc1nnc2c(Cl)cc(C(F)(F)F)cn12 +Cn1cnc(CNC(=O)c2ccccc2Br)n1 +Cc1ccc(NC(=O)Cc2c(C)nn(C)c2C)c(O)c1 +Cc1cccc2nc(-c3ccc(Cl)cc3)c(C(C)O)n12 +Cc1nc(CN(C)C(C)c2cccc(S(N)(=O)=O)c2)cs1 +Cc1ccc(C(C(=O)N2CCc3ncccc3C2)N(C)C)cc1 +CN(CCOc1ccccc1Cl)S(=O)(=O)c1cnn(C)c1 +Cc1cc(C)c(C)c(C(=O)CCN2CCOCC2)c1C +C=CCc1cc(CNc2ccc3c(c2)COC3)cc(OC)c1O +O=C(Nc1nccs1)C1CCN(C(=O)CCc2ccccc2)CC1 +CC1Oc2ccccc2OC1C(=O)Nc1cccc(Cl)c1 +CC(C)Cc1ncc(CN2CCCC2C(=O)OC(C)C)s1 +O=C(CSc1nncn1Cc1ccco1)Nc1ccc(F)cc1 +CC(C)NC(=O)CN1CCN(c2ccc(F)cc2)CC1 +CCOc1ccc(CC(=O)Nc2ccc(OC)cc2OC)cc1 +CCc1ccccc1NCC(=O)Nc1ccccc1C(=O)NC1CC1 +CC1=C(c2ccccc2)S(=O)(=O)c2ccccc21 +O=C(NCc1nc(-c2ccccc2)no1)c1cccc(-n2cnnn2)c1 +Cc1ccc(C)c(C(=O)Nc2ccccc2S(C)(=O)=O)c1 +CCC(C)NC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +Cc1cccnc1NC(=O)c1cccc(NC(=O)c2ccco2)c1 +COc1cc2nc(C3CCCCC3)n(CCC#N)c2cc1OC +CCn1cc(C(=O)NC2CCc3c(O)cccc32)c(C(C)C)n1 +COc1ccc(CC2Oc3ccccc3N(C(C)C)C2=O)cc1N +CC(=O)c1cc2c(cc1NC(=O)CCn1cnnn1)OCO2 +CC(C)NC(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +COc1ccccc1OCC(=O)N1CCN(C(=O)c2ccco2)CC1 +O=C(CC1C=CCC1)Nc1ccccc1NC(=O)c1ccc(F)nc1 +Cc1ccc(-n2nccc2N)cc1Br +COc1ccncc1NC(=O)COCc1nc(C)no1 +CC(C)N(C(=O)COc1ccc(F)cc1)C(C)C +Cc1nc(CCNC(=O)c2cc(C3CC3)nn2C(C)(C)C)cs1 +COc1ccc(Nc2ccc(S(C)(=O)=O)nn2)cc1 +CC(C)COCc1cncc2c1CCN(C(=O)c1ccncc1F)C2 +COC(=O)c1sc2nc(COC(=O)c3ccco3)[nH]c(=O)c2c1C +C=CCNC(=O)Cc1noc2c(CC)cc(N)cc12 +C=C(C)c1cccc(C(C)(C)NC(=O)Nc2cccnc2)c1 +Cc1cncn(CCNS(=O)(=O)Cc2cc(F)ccc2F)c1=O +Cc1ccc(SCC(=O)Nc2ccc(F)c(N)c2)cc1 +CCN(Cc1cccc(F)c1)C(=O)c1ccc(-n2cncn2)nc1 +CCCC(C#N)CC(=O)N1CCCc2ccccc21 +CCOc1ccc(F)c(C(=O)NC(C)C(=O)OC(C)(C)C)c1F +CC(=O)c1ccc2c(c1)N(CC(C)C)C(=O)C(C)S2 +COc1ccc2c(CCNC(=O)c3ccco3)c[nH]c2c1 +Cc1cc(C)n(-c2cccc(CN3CCCC(C#N)C3)c2)n1 +COc1cccc(CCNCc2ccccc2F)c1 +Cc1nccc(CNC(=O)c2ccc(-c3ccsc3)nc2C)n1 +COC(=O)c1c(-c2ccc(Cl)cc2)noc1NC(C)C +C=CCSc1nnc(NC(=O)c2cnc3ccccc3n2)s1 +COCCN(Cc1ccsc1)C(=O)Nc1ccccc1Cl +COCC(=O)N1CCCC2CN(C(=O)c3ccco3)CC21 +CNC(=O)Cn1c(-c2ccc(Cl)cc2)ccc(C#N)c1=O +CCc1noc(CC)c1CC(=O)NC(C)c1c(C)noc1C +COc1ccc(COc2ccc(N)cc2Cl)cc1F +CN(CC1CC1)C(=O)c1ccc(Br)cc1 +C=CCN(Cc1ccccc1)C(=O)c1ccc(COC)o1 +CCC(CO)NC(=O)NCC1CN(Cc2ccccc2)CCO1 +Cc1ccc(F)cc1CNc1ccc2cn[nH]c2c1 +CCCOC(=O)c1ccccc1NC(=O)c1ccco1 +COc1ccc(C(=O)NCCCO)c(OC)c1C +C=CCN(CCc1ccccc1)C(=O)c1cc(C)nc2c1c(C)nn2C +COc1ccccc1NCC(=O)Nc1ccc(CC#N)cc1 +Cc1ccccc1OCC(=O)NCC(O)c1ccsc1 +O=S(=O)(NCCc1ccccn1)c1ccc(Cl)c(Cl)c1 +CC1CN(CC(=O)N(C)Cc2cnn(C)c2)CCN1c1nccs1 +O=C1CN(C(=O)CNC(=O)c2cccc(Cl)c2)CCN1 +COc1cccc2c(=O)n(Cc3nc(C)cc(=O)[nH]3)cnc12 +Cc1oncc1C1NCCc2ccc(Cl)c(Cl)c21 +CCc1ccc(NC(=O)COc2nncc3ccccc23)cc1 +CC(C)(C)OC(=O)N1CCc2[nH]c(=O)c(S(C)(=O)=O)cc2C1 +CC(NC(N)=O)C(=O)N(C)Cc1ccc(Cl)cc1 +CCC(C)C(C)NC(=O)c1cccc(NC(C)=O)c1 +Cc1ncn(CC(O)COC(C)c2ccc(Cl)cc2)c(=O)c1C +Cc1cc(=O)c(OCC(=O)Nc2nc(C(C)(C)C)cs2)co1 +CC1(O)OC(COc2ccc(Cl)cc2)COC1O +O=C(NC1CC1)C(NCc1cc2ccccc2o1)c1ccccc1 +CC(C)NC(=O)Cc1ccc(NC(=O)c2cc(C(N)=O)cs2)cc1 +CCCNS(=O)(=O)c1cc2c3c(c1)C(C)C(=O)N3CCC2 +Cc1nc(CCNC(=O)CCc2ncc(-c3ccccc3)o2)cs1 +O=C1Cc2cc(NS(=O)(=O)c3cccc4ccccc34)ccc2N1 +O=C(Nc1ccc(C(=O)NC2CC2)s1)c1ccco1 +CC(=O)NC1CN(S(=O)(=O)N(C)C)CC1c1ccc(C)o1 +O=C(NCC#Cc1ccccc1F)c1ccc2[nH]cnc2c1 +Cc1occc(=O)c1OCc1ccc(Cl)c(Cl)c1 +COc1ccccc1-n1c(C)nc(=O)c(-c2ccccc2)c1C +CCOc1ccccc1C(=O)NCC(=O)NCc1nc(C)sc1C +CCC(O)CCNC(=O)Nc1ccc(Br)c(C)n1 +Cc1nc(C)c(CNCC(=O)NC(C)(C)C)s1 +O=C(NC1CCSc2ccccc21)c1cc(C2CC2)[nH]n1 +CCOC(=O)CSc1nnc(-c2ccco2)n1C +N#Cc1ccc(C(=O)NC2CCN(c3ccc(F)cc3)C2=O)cc1 +Cn1nnnc1-c1cccc(C(=O)Nc2ccc(C#N)cc2)c1 +CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccc[nH]c2=O)CC1 +COc1cc(N)cn2cc(-c3cccc(Cl)c3)nc12 +CC(C)CC1(CNC(=O)NC2CCCC2C(N)=O)CCCC1 +CN(C)C(=O)c1ccccc1NC(=O)c1ccc(Cn2cccc2)cc1 +CC(C)CC(=O)Nc1cc(-c2ccc(F)cc2)no1 +Cc1cccc(N2CC(c3nc4ccc(C)cc4[nH]3)CC2=O)c1 +CC(=O)N1CCCN(C(=O)C2CC(=O)N(Cc3ccccn3)C2)CC1 +O=c1cc[nH]c(-c2ccc(S(=O)(=O)N3CCCCC3)cc2)c1 +O=C(Nc1cc(-n2cnnn2)ccc1Cl)c1ccncc1 +COc1ccc(-c2cc(C(F)(F)F)n(-c3cc(C)nc(N)n3)n2)cc1 +CNC(=O)Nc1ccc(NC(=O)c2n[nH]c3ccc(C)cc23)cc1 +CCc1cccc(C)c1NC(=O)CNC(=O)c1cccc(OC)c1 +CCCOc1cccc(C(=O)Nc2nccs2)c1 +COC(=O)c1cc2ccccc2cc1NC(=O)c1ccnc(N(C)C)c1 +O=C(Nc1ccccc1)N1CCC(c2nnc3ccccn23)CC1 +CCCc1nnc(NC(=O)Nc2cnn(C)c2)s1 +COc1cccc(CNC(=O)c2cn[nH]c2-c2cccc(C)c2)c1 +CC(C)CCNC(=O)NC1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +CC(C(=O)N1CCCC1)N1CCN(C(=O)c2csnn2)CC1 +CCOC(=O)c1sc2ncn(Cc3cc(C)on3)c(=O)c2c1C +COC(=O)C1CCCN1C(=O)Nc1cccc(N)c1 +Cc1cc(C)cc(-n2ccnc2SC(C)C(=O)N(C)C)c1 +CCCN(CC(=O)OC)C(=O)c1cccnc1SC +Cc1oncc1C(=O)N1CC(c2ccccc2)C2(CCN(C)C2=O)C1 +COc1coc(Cn2ncc3ccccc3c2=O)cc1=O +O=C(NC1c2ccccc2CC1O)c1ccc(-n2cccc2)c(F)c1 +Cc1nc2ncc3c(=O)n(CC(=O)Nc4ncccc4C)ccc3n2n1 +O=C1CCC(C(=O)Nc2ccc(C(=O)Nc3ccccc3)cc2)N1 +Cc1ccc(NCc2ccc(F)c(C#N)c2)c(O)c1 +CCOC(=O)Nc1ccc(NC(=O)NCc2ccccc2)cc1 +O=C(Cc1ccccc1O)N1CCN(C(=O)c2ccc(F)cc2)CC1 +COC(=O)C(C)(C)NC(=O)Cc1csc(-c2cccc(C)c2)n1 +COc1ccc2c(cnn2CCC(=O)Nc2ccc(F)cc2)c1 +Cc1cc(NC(=O)c2nnsc2-c2ccccc2)no1 +COCCNC1(c2nc3c(s2)CCC3)CCOCC1 +N#Cc1ccccc1OCC(=O)NCC(O)C1CC1 +O=C(c1cnns1)N1CCC(c2ccccc2)CC1 +CN(CCc1ccncc1)C(=O)c1cnn(C)c1N +CCC(C)C(NC(=O)c1ccccc1Cl)C(=O)OC +Cc1cccc(NC(=O)C2CC2)c1-c1nc2ncccc2o1 +COc1ccc(CN(C)CC(O)c2ccccc2F)cc1 +CCC(C)NC(=O)COC(=O)c1ccc(Cl)cc1O +COc1ccc(CCC(=O)N2CCC(Cn3cccn3)CC2)cc1 +CS(=O)(=O)N1CCN(C(=O)COc2ccc(F)cc2F)CC1 +COc1cccc(CC(=O)NCC#Cc2ccc(C(N)=O)cc2)c1 +COC(=O)C(C)(C)NC(=O)c1cc(C(C)C)[nH]n1 +O=C(NC1CCN(c2ccccc2)C1)c1ccc(F)nc1 +CC(C)c1csc(NC(=O)c2cccc(N3CCOC3=O)c2)n1 +COCCN(CC(C)C)C(=O)c1cnn(-c2ccccc2C)c1C +CS(=O)c1ccc(NC(=O)CCn2ccc3ccccc32)cc1 +CCN(CC)S(=O)(=O)c1cc(NC(=O)CC(C)C)ccc1C +c1cc(CN2CCCC(c3cnccn3)C2)ccn1 +c1ccc(CN2CCOC3CN(c4nc(C5CC5)no4)CC32)cc1 +Cc1cc(C)n(C)c(=O)c1C(=O)NC(C)Cc1ccccn1 +Cc1nc(CCNC(=O)c2cccc(-c3ccoc3)c2)sc1C +COc1ccc(OC(C)C(=O)Nc2c(C)nn(C)c2C)cc1 +Cc1nn(C)c(C)c1C(C)C(=O)NC(C)c1cc2ccccc2o1 +CN(C(=O)Cn1nc(-c2ccco2)oc1=O)C1CC1 +CCOc1ccccc1CNC(=O)c1cnn(C)c1-n1cccc1 +COCC(C)NC(=O)C1CC(=O)Nc2cc(F)ccc21 +CCOC(=O)C1CCN(c2ccc(F)c(F)c2F)CC1 +O=C(Cc1ccccn1)N1CCN(C(=O)Nc2cccc(F)c2)CC1 +COC(=O)COc1c(C)cc(C(=O)NC(C#N)C(C)(C)C)cc1C +COCc1cccc(C(=O)Nc2ccc(C(C)=O)c(C)c2)c1 +CCC(NC(=O)c1cnn(-c2ccccc2OC)c1)c1ccnn1C +CC(C)c1ccc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)cn1 +Cn1cc(CCC(=O)Nc2ccc3ccccc3c2)cn1 +CNC(=O)c1cc(Cl)ccc1NCC(=O)NC(C)(C#N)C(C)C +COCCNC(=O)CCC(O)c1ccc(F)c(N)c1 +Cc1occc1C(=O)N1CCN2CC(Oc3cncnc3)CC2C1 +CCC(=O)N1CCN(C(=O)OC(C)(C)C)C(C)C1 +COc1ccc(Br)c(C(=O)Nc2ccccc2O)c1 +CC1CCN(C(=O)CNc2cccc(NC(=O)C(C)(C)C)c2)CC1 +Cc1cc(C)c(OCC(CC#N)N2CCCC2)cc1C +CN(C)C(=O)C1CC(=O)N(c2cccc(Cl)c2)C1 +Cc1ccc2c(c1)C(Nc1ccc(C#N)cn1)CO2 +Cn1cncc1C(=O)N1CCC2(CC1)NC(c1ccccn1)=NC2=O +Cc1ccsc1-c1nc2cnccn2c1NC(C)(C)C +Cc1nc(C(=O)N2CCC(c3nnc(-c4ccco4)o3)CC2)cs1 +CCOc1ccc(CNC(=O)c2nn3ccccc3c2Cl)cc1 +COC(=O)c1cc(CNC(=O)c2sccc2C)ccc1OC +CC(=O)NC1CCN(C(=O)C2Oc3ccccc3OC2C)CC1 +Cc1nnc2n(CC3CCCO3)c(=O)c3ccccc3n12 +COc1ccccc1Oc1ncnc(N2CCN(C(C)=O)CC2)c1N +Cc1cc(CN2CCN(c3nccs3)C(C)C2)on1 +Oc1ccc(N2CCN(CCOc3ccccc3)CC2)cc1 +COc1cc(C)ccc1NCC(=O)N1CCc2ccccc2C1 +CCc1nnc(CNc2cc(S(C)(=O)=O)ccc2F)o1 +C=CCn1cc(-c2cc(-c3cnn(CCC)c3C)nc(N)c2C#N)cn1 +COc1ccccc1C(=O)NCCc1ccccn1 +O=S(=O)(NCCN1CCOCC1)c1ccc(Cl)cc1 +CC(C)(C)OC(=O)N1CCCC1CNc1cnc2cc(N)ccc2n1 +CNC(=O)c1ccc(CNC(=O)N2CCOCC2CC(C)C)cc1 +N#CC(NC(=O)COCC1CC1)c1ccc(Cl)c(Cl)c1 +COc1ccc(C(C)(C#N)N2CCOCC2)c(OC)c1 +CCCn1nc(C)c(CN2CCOC(c3ccccc3C)C2)c1C +CC(C)Nc1nnc(SCc2cccc(C#N)c2)s1 +Cc1ccc(N2CCCC(CNC(=O)OC(C)(C)C)C2)nn1 +Cc1n[nH]c(C(=O)NCCc2c(F)cccc2F)c1Br +COc1ccc(OCCCC(=O)N2CCCC(C)C2)cc1 +CNC(=O)c1cccc(NC(=O)CN2CCCCC2=O)c1C +Cc1cc(C)c2nc(C)cc(C(=O)N3CCCC3Cn3cccn3)c2c1 +NC(=O)COC(=O)COc1ccc(Cl)cc1Br +O=C(NCc1ccccn1)c1cc(-c2ccco2)nc2ccccc12 +CCCNC(=O)c1cccc(Br)c1N +Cc1ccccc1CNC(=O)COn1nnc2ccccc21 +Cn1c(SCCOc2ccc(C#N)cc2)nnc1-c1ccncc1 +FC(F)(F)c1cnc(-c2ccnc(-c3cccnc3)n2)c(Cl)c1 +CC(=O)N1CCN(S(=O)(=O)Cc2ccccc2)CC1 +Cc1noc(CCC(=O)NCCc2ccc(-n3cccn3)cc2)n1 +CCN(C(=O)CNc1ccccc1Cl)C1CC1 +O=C(NCCNC(=O)C1CC1)c1ccc(C(F)(F)F)cc1 +Cc1cccc(C)c1NC(=O)c1ccc(-n2cncn2)nc1 +Cc1cc(NC(=O)c2nnn(-c3cccc4ncccc34)c2C)no1 +Cc1cncc(C(=O)N2CC3CCC2C3OCC2CC2)c1 +Cc1n[nH]c(-c2cccc(CNC(=O)C3CN(C)CCO3)c2)n1 +CNCC1NCCc2cccc(Br)c21 +CC(C)Nc1ccnc(N2CCN(C(=O)C3(CO)CC3)CC(O)C2)n1 +COc1ccc(Nc2oc(C)cc(=O)c2C(C)=O)cc1 +CCCNS(=O)(=O)c1ccc2c(c1)N(C)CC(C)(C)O2 +CCOC(C)C(=O)NCCNC(=O)c1cccc(Br)c1 +CC1CN(CCCNC(=O)NCc2ccc3c(c2)CCC3)CC(C)O1 +Cc1cc(C)c2oc(C(=O)NCc3ccccc3)cc(=O)c2c1 +NC(=O)CC1CCN(C(=O)Nc2ccc(C(F)(F)F)cc2)CC1 +Cc1cc(C(=O)CCC(=O)NCC2CCCO2)c(C)s1 +Cc1ccc(CCNC(=O)c2ccnc(OC3CCC3)c2)cn1 +Cc1cc(C)n(CC(=O)NCc2ccccc2F)n1 +NC(=O)c1cccc(S(=O)(=O)N2CCCC2Cc2ccccc2)c1 +CSc1ccc(C(=O)Nc2nnc(-c3ccno3)o2)cc1 +Cc1cc(C(=O)NC2CC3CCC2(C)C3(C)C)no1 +O=C1CC(C(=O)N2CCOC3CCCC32)CN1Cc1ccco1 +C=CCn1c(SCC(=O)Nc2c(C)cccc2C)nnc1C1CC1 +O=C(COc1ccc(OCc2ccccc2)cc1)Nc1cccnc1 +COC(=O)c1occc1CN1CCOCC1CC(C)C +O=C(CSc1nnc(-c2cccnc2)o1)Nc1ccc(Cl)cn1 +CN(C(=O)NCc1ncn(C)n1)C1CCCCC1 +CC=CCOC(=O)C1CCN(S(=O)(=O)CC)CC1 +Cc1nc(CC(=O)N(C)CCOc2ccccc2)cs1 +CCCn1cccc(-c2nnc(NC(C)C)s2)c1=O +O=S1(=O)N=C(NCc2nnc3ccccn23)c2ccccc21 +O=C(CCNC(=O)c1ccco1)NC(CO)c1ccccc1 +Cc1cc(Cl)ccc1S(=O)(=O)Oc1cccc(-n2cncn2)c1 +COc1ccc(NC(=O)c2ccc(C)c(O)c2)cn1 +Cc1ccccc1-c1nnc2n1NC(C)C(C)S2 +CN(CC(=O)NC1COc2ccccc21)c1cnccn1 +CC1CCCC(OC(=O)C2COc3ccccc3O2)C1 +O=C(CCC(=O)N1CCNCC1)c1ccc2c(c1)OCCO2 +Cc1cc(C)cc(N2CC(C(=O)N3CCN(C)CC3)CC2=O)c1 +O=C(CCc1ccccn1)Nc1ccc(Br)cc1 +Cc1ccc(C)c(C(=O)Nc2ccc3c(c2)NC(=O)CS3)c1 +Nc1nonc1-c1nc2ccccc2n1CC(=O)Nc1ccccc1 +Cc1cnc(C(=O)NCCc2ccc3c(c2)OCCO3)cn1 +Cc1nn(C)c(C)c1OCc1cccc2c1OCCO2 +COc1c(C)cc(CN(C)C(=O)c2cn[nH]c2C)cc1C +CNc1nc(-c2cc(C)n(-c3nccs3)c2C)cs1 +CCn1nnc2cc(C(=O)NCCCC#N)ccc21 +Cc1ccc(-c2nc(-c3cccnc3)no2)c(C)c1 +Nc1noc2nc3ccc(Br)cc3cc12 +NS(=O)(=O)N1CCc2ccc(NC(=O)COCC3CC3)cc21 +COCc1nc(C(=O)OC(c2ccccc2)c2cccnc2)cs1 +COCSc1nc(C)c(C)n1C1CCCCC1 +COc1ccc(CC(=O)Nc2ccccn2)cc1OC +Cc1ccnn1-c1ccc(C(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +Cc1ccc2c(CC(=O)N3CCC(N4CCNC4=O)CC3)coc2c1 +CC(C)(C)c1ncc(C(=O)Nc2c[nH]ccc2=O)s1 +CC(=O)NCc1ccc(C)cc1OCc1ccco1 +Cc1ccc(=O)n(CC(=O)N2CCC(Oc3cccc(Cl)c3)C2)n1 +Cn1cnc2ccc(C(=O)N3CCOCC3)cc2c1=O +COc1ccc(CNC(=O)c2cccc(Cl)c2)c(OC)c1 +CC(=O)Nc1ccc(CC(=O)N2CCC(C)CC2)cc1 +Cn1cc(C(=O)N2CCC(c3cc4ncccc4c(=O)[nH]3)CC2)cn1 +COc1ccc(C(O)CNC(=O)c2ccc(F)cc2)cc1 +CCOc1cccc(-c2cccc(-n3cnnc3)c2)c1 +CSc1ccc(CNC(=O)c2cc(-c3cccs3)[nH]n2)cc1 +COc1ccc(NC(=O)c2ccccc2OC)c(OC)c1 +CNC(=O)c1cccc(S(=O)(=O)NCCOC)c1 +Cc1nn(C)c(C)c1C(=O)Nc1cc(=O)n(C)c(=O)n1C +Cc1cnc(CCNCc2cccc3c2OCCCO3)s1 +CC(CNC(=O)NCC1Cc2ccccc2O1)N1CCOCC1 +CC(=O)NC(c1c(O)n[nH]c1C)C(Cl)(Cl)Cl +Cc1cc(CC(=O)NC2CCCCC2OCCC(C)C)n[nH]1 +CC(=O)N1CC2CCCCC2Nc2ccsc21 +COc1cc2[nH]c(=O)c(CN3CC=CC3CO)cc2c(OC)c1OC +CC(NS(=O)(=O)c1ccccc1F)C(=O)Nc1ccncc1 +CS(=O)(=O)c1ccccc1-n1cc(NC(=O)NCC2CC2)cn1 +OCc1ccc(-c2nccn2CCCCc2ccccn2)o1 +O=C(COC(=O)Cc1c[nH]c2ccccc12)NCC(F)(F)F +CCc1noc(CC)c1CNC(=O)c1cccc(-c2noc(C)n2)c1 +Cc1nc(C(=O)N2CCC(Oc3cccnn3)CC2)cs1 +NC(=O)c1ccccc1OS(=O)(=O)c1cccc(F)c1 +CCC(=O)Nc1nc2c(OC)cc(NC(=O)NC)cc2s1 +COC(=O)C(Cc1ccccc1)NC(=O)c1ccc2c(ccn2C)c1 +Cc1n[nH]c(SCc2nc(CC(=O)NCc3ccccc3)no2)n1 +CC(=O)NC(C)C(=O)NC1(c2ccccc2)CCCCC1 +O=C1C2CCCN2C(=O)c2ccccc2N1Cc1ccccc1F +CCCNS(=O)(=O)c1ccc2c(c1)NC(=O)C(C)(C)N2 +Cn1c(=O)[nH]cc(C(=O)Nc2ccc3c(c2)Cc2ccccc2-3)c1=O +CC1(C)CCCC1NC(=O)NCc1cn(-c2ccccc2)nn1 +COC(=O)c1sccc1NC(=O)Nc1ccc(C)cc1 +COC(=O)C1=C(C)N(C(C)C)C(=O)NC1c1cccnc1 +Fc1ccc(-c2cnc(CSc3nncs3)o2)cc1 +COc1ccccc1C(=O)NCCC(=O)NCC1CCCCC1 +CS(=O)(=O)N1CCCC(c2cncc(N3CCOCC3)n2)C1 +CC(=O)N(CCc1ccccc1)CC(=O)N1CC(C(N)=O)CCC1C +CCCC(C)NC(=O)CSc1nnc(-c2ccoc2C)o1 +N#CCCN(CCC#N)C(=O)c1cc2ccccc2o1 +COC(Cn1cc(-c2nccn2C)nn1)c1cccs1 +O=C(Cn1c(C2CC2)nc2ccccc21)N1CCCC(c2ccn[nH]2)C1 +CN(Cc1ccccn1)C(=O)Nc1ccc(F)c(Cl)c1 +O=C(COc1ncnc2c(Cl)cc(Cl)cc12)N1CCOCC1 +Cc1ccc2cccc(C(=O)N3CCN(c4ncccn4)CC3)c2n1 +CN(Cc1nccs1)C(=O)C1CCC(=O)N(C2CCCCCC2)C1 +COC(C)(C)CC(C)Nc1c(C)nn(C(C)C)c1C +O=C(Cc1c[nH]c2ccccc12)NCc1cn[nH]c1 +Cc1nc(NC(=O)C2COc3ccc(F)cc3C2)cc(C2CC2)n1 +CC(=O)Nc1ccccc1C(=O)Nc1cccc(C)c1C +Cc1nn(C)c(C)c1CC(C)C(=O)N1CCc2ccc(Cl)cc2C1 +CC(=O)NCc1ccc(C(=O)OC2CCCC(C)C2)cc1 +C=CCNC(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 +O=C(c1scnc1C1CC1)N1CCOC2(CCc3ccccc32)C1 +c1ccc(N2CCN(c3cc(C4CC4)nc4ncnn34)CC2)cc1 +O=C(NCc1ccc(F)cc1)c1cccc(N2CCCS2(=O)=O)c1 +OCc1cc(F)cc(CO)c1OCc1ccn(-c2ccccc2)n1 +Cc1cccc(N(C)C(=O)C2CC(=O)N(C)C2c2cccnc2)c1 +CC(=O)N1CCN(C(=O)C(O)c2ccc(C)c(C)c2)CC1 +CCOC(=O)c1nnn(-c2nonc2N)c1CSc1ccccn1 +COc1ccc2c(c1)CC(NC(=O)Nc1cccc(C(C)=O)c1)CO2 +Cc1ccc(C(=O)NCCCCNc2ccc(N)cn2)cc1 +CCCOc1ccccc1-c1ccc(C(C)(C)O)c(=O)n1C +CC(c1ccccc1Cl)N(C)C(=O)c1ccc(CNC(N)=O)cc1 +N#CCCn1nc(-c2ccc(F)c(F)c2)c2c1CCNC2 +CCCCCN1C=NS(=O)(=O)c2ccccc21 +COc1ncccc1NC(=O)NC(CCCO)c1ccccc1 +Cc1ccc2c(c1)CCCN2C(=O)CCNC(=O)c1ccco1 +Cc1cc(C)n(C(C)C(=O)Nc2ccccc2C(F)(F)F)c(=O)n1 +COc1ccc(CC(=O)N2CCC(O)CC2)c(OC)c1 +CCS(=O)(=O)NCC(=O)Nc1cc(CC(C)(C)C)n[nH]1 +Cn1c(C(=O)NCc2nnc3n2CCC3)ccc1-c1ccc(F)cc1 +CCCCS(=O)(=O)NC(C)c1cccc(N2CCCC2=O)c1 +CNC(=O)CNC(=O)c1ccccc1OCCOC +O=C(c1cccn1C1CC1)N1CCC(Cc2ccc(CO)cc2)C1 +CCC(Cn1ccnc1)n1cnc2sc(C)c(C)c2c1=O +NC(=O)CSc1nnc(-c2c[nH]c3ccccc23)n1C1CC1 +CCC1c2ccccc2CCN1C(=O)C(C)Sc1nncn1C +CCCCCNC(=O)Nc1ccccc1N1CCCC1=O +CC(C)C(=O)N1c2ccc(C(=O)CN)cc2CC1C +Cc1noc(COC(=O)Cc2c[nH]c3c(C)cccc23)n1 +COc1ccc(C)cc1NC(=O)CCNC(=O)Cc1ccccc1 +CS(=O)(=O)NC1CCN(c2ccc(Cl)c(Cl)c2)C1=O +CCCCn1ncc(C(=O)NCC(C)(C)c2ccncc2)c1C +CN(C)c1ccccc1C#CCNC(=O)c1ccc2ccccc2n1 +CCc1onc(C)c1NC(=O)NCC1(C)CCC1 +C=CCNc1nc(-c2cnn(CC)c2C)cc(C(F)(F)F)n1 +CSc1nc2ncnc(N(C)Cc3cnn(C)c3)c2s1 +Cn1cnc2cc(OC(=O)Nc3ccc4c(c3)OCO4)ccc21 +Cc1ccc(C(=O)N2CCN(C(=O)CCOC(C)C)CC2)cc1 +O=C(NCc1ccoc1)Nc1ccc(CN2CCOC2=O)cc1 +CCn1cc(NS(=O)(=O)c2ccc3c(c2)NC(=O)CO3)cn1 +CNC(=O)c1cc(Cl)ccc1NC(=O)CCOCc1ccccc1 +CCc1nc(CNCc2ccccc2C(F)(F)F)cs1 +Cc1cccc(OCc2nnnn2C(C)C)c1F +Cc1occc1C(=O)Nc1cc(Cl)ccc1Cl +CCc1ncc(C(=O)NC(C)Cc2ccncc2)cn1 +Nc1ccc(NC(=O)c2ccc(Cl)cc2F)c(Cl)c1 +CCCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(OC)c(OC)c1 +CCc1noc(CC)c1CNC(=O)c1ccc2[nH]cnc2c1 +Cc1noc(C)c1COC(=O)Cc1c[nH]c2ccccc12 +Cc1cnc2c(S(=O)(=O)NCc3ccco3)cccc2c1 +CC(C)CN(C(=O)c1ccc(F)cc1Br)C1CC1 +Cc1ccc(N2CC(C(=O)NCc3cccs3)CCC2=O)cc1C +Nc1ccc2nc(CC(=O)Nc3nccs3)ccc2c1 +NS(=O)(=O)c1cccc(CNC(=O)CC2CCc3ccccc32)c1 +CC(C)(C)OC(=O)Nc1ccc(CCNC(=O)c2csnn2)cc1 +Cn1cnc2cc(C(=O)OCCN3CCCCC3=O)ccc21 +COCCCNS(=O)(=O)c1cc(C(C)=O)ccc1Cl +O=C1OCCC1OC(=O)C(c1ccccc1)c1ccccc1 +Cc1ccc(CN2C3=NC(=O)CN3c3ccccc32)cc1 +O=S(=O)(NCc1ccoc1)c1ccc2ccccc2c1 +CCn1nccc1C(=O)Nc1nnc(Cc2ccc(C)c(C)c2)o1 +O=C(NCc1ccc2c(c1)OCCO2)c1ccc(-n2cncn2)cc1 +COc1ccc(CC(=O)Nc2ccc(C)c(N)c2)cc1 +Cc1nn(-c2ccccc2)nc1C(=O)Nc1nc(C(C)C)cs1 +O=C(Nc1ccc(N2CCCC2=O)cc1)c1cccc(Cl)c1Cl +O=C(Nc1noc2ncccc12)C12CC3CC(CC(C3)C1)C2 +COc1ccc(OC)c(CNS(=O)(=O)c2ccc(C)s2)c1 +Cc1noc(C)c1CCC(=O)Nc1nc(-c2cccnc2)cs1 +CCC(C)NC(=O)c1ccc(-c2ccc(Cl)cc2)nc1N +Cc1ccc(-c2nnco2)cc1NC(=O)c1ccc(O)cc1F +O=C(CS(=O)(=O)c1ccc2ccccc2c1)N1CCCCCC1 +Cc1ncncc1C(=O)N(CCC#N)C12CC3CC(CC(C3)C1)C2 +NC(=O)Cn1c2ncccc2c(=O)n1-c1ccccc1 +Cc1noc2ncc(C(=O)N(CCO)C(C)C)cc12 +CC(=O)c1cccc(Nc2ncnc(NC(C)C)c2N)c1 +O=C(Nc1nc(-c2ccccc2)ns1)c1cnns1 +CCOc1ccccc1NC(=O)c1csc(Nc2cccnc2)n1 +NC(=O)c1ccc(-c2nnn(CCCOc3ccccc3)n2)cc1 +CCc1nnc(NC(=O)NCc2cc(C(=O)OC)c(C)o2)s1 +CC1CCCN(C(=O)c2scnc2C2CC2)C1 +COc1ncccc1C(=O)NCc1ccc(OCc2cccnc2)cc1 +CC(C)Cc1cc(C(=O)N2CCCC2c2ccncc2)[nH]n1 +CC(NC(=O)CSc1nnc2[nH]c3ccccc3n12)c1ccco1 +CCc1ccc(NC(=O)c2cc(=O)c(OCc3ccccc3)co2)cc1 +Fc1ccccc1-c1cc(NC2CC2)n2nccc2n1 +C=CCNS(=O)(=O)c1ccc(C(=O)Nc2cccc(C)c2)cc1 +COC(=O)C(C)OC(=O)c1c(C)nn(-c2ccccc2)c1C +COc1cc(CN2C(C)COCC2C)ccc1SC +Cn1c(=O)c2c(nc3n2CCCN3C2CCCC2)n(C)c1=O +CCN(CC)C(=O)c1ccc(NC(=O)CC2C=CCC2)cc1 +COCc1ccccc1CNS(=O)(=O)c1cc(C(N)=O)n(C)c1 +Cc1ccc(C(=O)NC2CC(=O)N(Cc3ccccc3)C2)cn1 +CCC(NC(=O)Cn1nc(C)c(N)c1C)C(C)C +CCCOc1cccc(-c2ccc(C(=O)NC)c(N)n2)c1 +Cc1n[nH]c(C(=O)NCCC(=O)N2CCCCC2)c1Br +COc1ccncc1NC(=O)C(c1ccccc1)N1CCCCC1=O +CC(C)(C)NS(=O)(=O)c1cccc(Cl)c1Cl +CCCN1C(=O)c2cccc3c(S(=O)(=O)NCCCO)ccc1c23 +Cc1cc(CS(=O)(=O)NCC(C)N2CCOCC2)no1 +O=C(NCc1nnc2n1CCCC2)NC1CCCCc2ccccc21 +O=C(CN1CCN(C(=O)c2ccco2)CC1)Nc1cccc(Cl)c1 +COCCN(Cc1cccnc1)C(=O)c1ccc(OC)nn1 +CCN(CC)C(=O)N1CCC(C(=O)N(c2ccccc2)C(C)C)CC1 +Cc1ccc(S(=O)(=O)CCC(=O)Nc2cc(C)on2)cc1 +Cc1cccnc1NC(=O)c1cc2sccc2n1C(C)C +O=C(Cc1ccc(F)cc1)N1CCC2(CC(OCC3CC3)CO2)C1 +COc1ccc(OCCC(=O)NC(C)c2ccc(C)o2)cc1 +COc1ccc(C(=O)Nc2ccc(OC)c(Cl)c2)cc1N +CC(=O)Nc1ccc(F)c(NC(=O)N(C)Cc2ccc(C#N)cc2)c1 +C=CCn1c(CC)nnc1SCC(=O)Nc1cccc(C#N)c1 +Cc1ccc(NC(=O)CNC(N)=O)cc1OCC(F)F +Cc1ccc(-c2cc(NC(=O)C3CNC(=O)N3)[nH]n2)s1 +N#Cc1ccccc1S(=O)(=O)Nc1ccc(F)cc1Cl +O=C(NC1CCSc2ccc(F)cc21)c1cnc2ccccc2n1 +CC(C)COCCNC(=O)N1CCc2sccc2C1 +O=C(COc1ccc(F)cc1F)NCc1ccc2c(c1)OCO2 +CCOc1ccc(S(=O)(=O)n2c(C)nc3ccccc32)cc1 +O=C(Cc1c(F)cccc1F)N1CCN(C(=O)c2ccccc2)CC1 +CCCNC(=O)C(C)Sc1nnc(-c2ccccc2Cl)n1C +Cc1ncc(CNC(=O)c2cc(Cl)ccc2Cl)s1 +Cc1cc(CC2COCC2NC(=O)CSc2nncn2C)on1 +Cc1ccc(C(=O)C2CCCN2S(=O)(=O)N(C)C)cc1C +CCC1CCCN(C(=O)Nc2ccc(OC)cc2OC)C1 +CCc1ccc(C(=O)Nc2ccc(-n3ccnc3)nc2)s1 +CCCN(Cc1cc2cccc(C)c2[nH]c1=O)C(=O)C(C)C +O=C(Nc1cccc(-n2cnnc2)c1)c1ccc(-n2ccnn2)cc1 +CCOC(=O)C1CCCN(C(=O)Nc2ccc(SC)cc2)C1 +Nc1nc(N2CCCC3(CCC(=O)N(CCO)C3)C2)cc2nncn12 +COc1ccc(OCc2nc(C(=O)NC(C)C)co2)cc1 +O=C(CCCC(O)c1ccc(F)cc1)N1CCCC1 +COc1cccc(C(=O)N(C)C(C)C(C)(C)C)c1O +Cc1ccc(C(=O)N(Cc2cc3c(s2)CCC3)C(C)C)c(=O)[nH]1 +N#Cc1nc(C2CC2c2ccccc2)oc1N1CCOCC1 +COc1cccc(NC(=O)Nc2ccc3c(c2)C(=O)NCC3)c1OC +CC(=O)NC(C)(C)c1noc(-c2cc(-c3ccccc3F)on2)n1 +CC(=O)c1csc(NC(=O)Cn2nc3ccccn3c2=O)n1 +O=C(NCc1ccncc1)c1ccc(OCC(F)(F)F)cc1 +COc1ccc(CNc2c(C)cccc2C)cc1OC +CC(=O)Nc1cc(Cl)ccc1OCC1CCCO1 +CC(C)Oc1cccc(-c2cc(C3CCOC3)c(C#N)c(N)n2)c1 +N#CCCCOc1cccc(NC(=O)C2CCCN2C(=O)C2CC2)c1 +COc1ccc(F)cc1NC(=O)Cc1ccc(N2CCCC2=O)cc1 +CC1CC(Cc2ccccc2CC2CC(C)OC2=O)C(=O)O1 +CCC1CN(C(=O)CSc2nc(C)cc(N)n2)CCO1 +COCCC(C)C(=O)Nc1ccc2c(c1)nc(C(C)(C)C)n2C +O=C(NCCc1nccs1)c1cc(-c2ccc3c(c2)CCO3)n[nH]1 +CC(C)c1cc(C(=O)N2CCC(C(N)=O)C2)c2ccccc2n1 +CCC(CC)C(=O)OCc1cc(=O)n2c(C)csc2n1 +CCC(=O)N(C)CC(=O)Nc1c(Cl)cccc1Cl +Cc1cc(C(=O)NCc2ccnc(-n3ccnc3C)c2)on1 +O=C(C1CC1)N1CCC(Nc2cc(N3CCCC3CO)ncn2)CC1 +CCn1nnnc1-c1cccc(C(=O)NCC2CCCO2)c1 +COc1ccccc1C1(C(=O)Nc2ccc3c(c2)C(=O)NCC3)CC1 +O=c1c2ccccc2cnn1CC(O)COCc1ccccc1F +O=C(NCC1CCCO1)c1ccc(-c2ccccc2)[nH]c1=O +CC(C(=O)Nc1cccc(F)c1F)n1cccn1 +Cc1nnc(NC(=O)c2csc3c2CCC(C)C3)s1 +CCc1noc(C)c1C(=O)N1CCN(CC(=O)NC2CC2)CC1 +CCc1cc(N2CCC(C(C)N3CCOCC3)CC2)ncn1 +C=CCN(Cc1ccccc1OC)C(=O)c1c(C)nn(C)c1C +Cc1cccc2c1C(=O)N(C)C(c1cccc(C#N)c1)N2 +Brc1ccc(OCc2nc(-c3cccnc3)no2)cc1 +COc1ccc(NC(C)=O)cc1Nc1ccc2nnnn2n1 +CCC(CC)C(CNC(=O)Nc1cc(C)nn1C)N1CCOCC1 +O=C(Nc1ccc(Oc2ccccc2)cc1)C1C2CC3OC(=O)C1C3C2 +COc1ccccc1-c1nnc2sc(-c3ccncc3)nn12 +COc1ccccc1-c1n[nH]c(NC(=O)c2ccc(SC)cc2)n1 +Cc1nc(Cn2cc(CCCO)c(C(F)(F)F)n2)oc1C +COc1ccc(C(O)c2cccs2)c(Cl)c1 +CC#CC(=O)N1CCc2onc(-c3ccc(Cl)cc3)c2C1 +COC(=O)c1ccc(COC(=O)c2cnccn2)o1 +CN(Cc1cnn(C)c1)C(=O)CNc1ccc(-n2cccn2)c(F)c1 +CCN(c1ccc(F)cc1C(C)=O)C(C)COC +COCCNc1ccccc1CNC1=NS(=O)(=O)c2ccccc21 +Cc1cc(C)c(C(=O)NCCCc2nc3ccccc3n2C)c(=O)[nH]1 +CNC(=O)c1ncn2c(N)c(C(=O)Nc3cccc(OC)c3)nnc12 +Cc1cc(C(=O)N2CCn3c(C)nnc3C2)c2c(C)n[nH]c2n1 +Cc1cccc(NC(=O)Cc2ccc(F)c(F)c2)c1C(N)=O +Cc1cnn(CCC(=O)NC(C)c2ccc(C)o2)c1 +Cc1ccsc1C(=O)N1CCC(O)C1Cc1cnn(C)c1 +CC(C)Sc1ccccc1NC(=O)c1cccc(-n2cnnn2)c1 +NC(=O)CCCNC(=O)c1csc(-c2c(F)cccc2F)n1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccc2[nH]c(=O)[nH]c2c1 +OCc1cccc(NCc2ccc3c(c2)CCO3)c1 +Cc1cc(C)cc(C(=O)N2CCN(c3c(C)n[nH]c3C)CC2)c1 +CCOc1ccccc1CNC(=O)Nc1ccccc1OC +Cn1c(SCc2cccnc2)nc2c(c1=O)SCC2 +O=C1CC2(CCN(C(=O)c3cccc(F)c3)CC2)CN1 +Cc1cc(NC(=O)c2csc(-c3ccc(Cl)cc3)n2)no1 +Cc1cccc(CNc2ccc3c(c2)OCC(=O)N3C)c1 +O=C(COc1ccc(Cl)cc1-n1cnnc1)Nc1ccc(O)cc1 +CC(c1cn(-c2ccccc2)nn1)N1CCCN(c2ncccn2)CC1 +Cn1nc(CCOc2ccccc2Cl)cc1N +NC(=O)CC1CCCCN1C(=O)c1cccc(Cl)c1 +Fc1cc(Cl)cc2c1CCNC2c1ccncc1 +CCOc1cc(C)nc(N2CCN(C(=O)c3occc3C)CC2)n1 +O=C(Nc1cccc(Oc2ccccc2)c1)c1cn2cccnc2n1 +CC(NC(=O)N1CCC1)c1cccc(S(N)(=O)=O)c1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NCc1ccncc1 +O=C(NCc1ccncc1)Nc1ccc2ccccc2c1 +Cc1cc(C(=O)Nc2nc(-c3ccccc3)c(C)s2)c(C)o1 +Nc1cc(C(F)(F)F)ccc1OCc1cccnc1 +Cc1cc(C(O)CCN2CCOCC2)ccc1Br +COc1ccc(NC(=O)N(CCO)C(C)C)c(C)c1 +Cc1ccc(C2COCCN2C(=O)c2ccnc(OC3CCC3)c2)o1 +CCN(CCC(=O)Nc1ccc(C(N)=O)cc1)C(=O)c1ccoc1C +CCOC(=O)CCC(C)NC(=O)N1CCC(c2ccn[nH]2)CC1 +CC(Nc1ccc(S(C)(=O)=O)cc1N)c1cccs1 +Cn1c(C(=O)N2CCN(S(C)(=O)=O)CC2)cc2sccc21 +COCCN(Cc1cnn(C)c1)C(=O)c1onc2ccccc12 +Cc1cc(C(=O)Nc2ccc(-n3ncc(C#N)c3N)cc2)c(C)s1 +CCOC(=O)c1cc2nccn2cc1Br +Cc1nn2cc(C(=O)NCc3ccc(Cl)c(Cl)c3)nc2s1 +CNc1snc(C)c1C(=O)N1CCN(Cc2cccs2)CC1 +O=C(COc1ccc(F)cc1F)NCc1ccc(-n2cccc2)cc1 +CCOC(=O)c1[nH]c(=O)[nH]c1CSn1nc(C)cc1C +CC(c1ccccc1)n1nc(C#N)cc1-c1ccncc1 +Cc1nc(N2CCN(C(=O)C(C)C)CC2)c(C#N)c2c1CCCC2 +CC(Sc1ccccn1)C(=O)Nc1cccc(Cl)c1 +O=C(CCn1ccccc1=O)Nc1ccccc1Oc1ccccc1 +CNC(=O)c1cccc(NC(=O)NCc2ccccn2)c1C +Cc1cnc(NC(=O)N(C)CC(C)(CO)CO)s1 +Cc1cc(C(=O)NCC(C)O)c(C)n1C1CCCCC1 +Cc1csc(NC(=O)c2cc(Br)cn2C)n1 +CN(C)C(=O)CC(C#N)c1ccc(C(C)(C)C)cc1 +CC(=O)Nc1cc(NC(=O)CN(C)C(C)=O)ccc1F +CCC(=O)NC1CC(C(=O)N(CC)CC)N(C(=O)c2cncn2C)C1 +CC(=O)NCC1CCN(c2nc3c(s2)c(C)nn3C)CC1 +CC(C)c1nc(NCCO)c(C#N)c2c1CCCC2 +Cc1onc(-c2ccccc2)c1C(=O)Nc1ccc2c(c1)OCO2 +Cc1occc1-c1nnc(SC2CCN(C)C2=O)n1C +NC(=O)CSc1nnc(-c2cccnc2)n1Cc1ccccc1 +CC(C)NC(=O)Cc1nc(CNc2ccc(Cl)cc2)n[nH]1 +Cc1ccc2ncc(C(=O)NCC3(C(N)=O)CCOCC3)c(=O)n2c1 +CCOc1nc(Sc2nc(C)cs2)ccc1N +O=C(Nc1nc[nH]n1)c1ccc(Br)c(F)c1 +N#CC(NC(=O)c1ncn(-c2ccccc2)n1)C1CCCCC1 +CC(NS(=O)(=O)c1cccs1)C(=O)Nc1cn[nH]c1 +Cc1ccc(C)c(-c2csc(CCN3CCOC3=O)n2)c1 +COCc1nnc(NC(=O)Cc2ccc(F)cc2)s1 +CC(O)c1ccccc1NC(=O)c1cnn(-c2ccc(F)cc2)n1 +CCCCCN(C(=O)Cn1ccc(N)n1)C(C)C +c1ccc(Nc2nc(C3CCCN3c3ccncn3)cs2)nc1 +Cc1ccc(C)n1NC(=O)COc1ccc(Cl)cc1Cl +CC(C)N(C)C(=O)NCCCNC(=O)OC(C)(C)C +O=C(CNc1ccc2nnc(C(F)(F)F)n2n1)N1CCCC1 +Brc1cccc2c1C(C1CCC1)NCC2 +CC(NC(=O)c1cccs1)C(=O)N(CCC(N)=O)c1ccccc1 +N#CC1(C(=O)NCc2ccnc(OC3CCC3)c2)CCC1 +Cc1ccc(C(O)C(=O)Nc2ccc3c(c2)OCCO3)c(C)c1 +Cc1ccccc1C(CC(=O)NC(C)(C)CC(C)(C)C)NC(N)=O +CC1CNc2cc(-c3nc(-c4ccncc4)cs3)ccc2O1 +CC(=O)NCc1ccc(C(=O)N2CCOC(C)(C)C2)cc1 +CNC(=O)c1ccc(OC)c(NC(=O)Cc2ccc(F)cc2F)c1 +CS(=O)(=O)NCc1nnc2n1CCN(Cc1cccnc1)C2 +CC1CCN(C(=O)c2cccc(NCC(=O)NC(C)C)c2)CC1 +Cc1ccc(CNc2nnc(C3CCCCC3)o2)nc1 +COc1cc(C)sc1C(=O)Nc1ccc2oc(=O)n(C)c2c1 +Cc1[nH]ncc1CCCNC(=O)NCC1(c2ccc(F)cc2F)CC1 +CN(C(=O)Cn1c(=O)cnc2ccccc21)C1CCCC1 +Oc1ccc(N2CCN(c3ncnc4nc[nH]c34)CC2)cc1 +Fc1ccc(-c2nc3cc4c(cc3[nH]2)OCCO4)c(F)c1F +CCN(CC)C(=O)c1cc(NC(=O)c2ccccc2C)c(=O)n(C)c1 +OC1(c2ccccc2)CCn2nnc3cccc1c32 +O=C(Cc1cccs1)N1CCC(n2cccn2)CC1 +CCCOc1ccc(C(=O)NCc2c[nH]nc2C)cc1 +CCOc1ccc(NC(=O)c2cc(CN3CCOCC3)on2)cc1 +O=C(NCC1(O)CCCC1)c1ccc(Cl)cc1Cl +CCOC(=O)c1cnc2c(c1)c(=O)n(C)c(=O)n2-c1ccc(F)cc1 +CC(C)N(CCSc1ccccc1)C(=O)c1c[nH]c(=O)[nH]1 +COCc1nc(C(=O)Oc2ccccc2C(F)(F)F)cs1 +Cn1cc2c3c(cccc31)CN(C(=O)CC(C)(C)C)CC2 +Cc1ccc(Br)c(NC(=O)CCn2cc(C)cn2)c1 +CC(C)Sc1ccccc1C(=O)Nc1cnn(CC2CCCO2)c1 +Cc1ccc(CC(=O)Nc2nc(-c3ccncc3)cs2)c(C)c1 +CNC(=O)CC(c1ccc(OC)cc1OC)C1CC1 +Cc1cc(=O)[nH]c(-c2ccc(NCCCNc3ncccn3)nc2)n1 +c1ccc(CNc2nnnn2-c2ccccc2)cc1 +O=C1NC(c2ccc(OCC3COCCO3)cc2)Oc2ccccc21 +Cc1nn(CC(C)C)c(C)c1CC(=O)NC(C)CO +Cc1noc(C)c1CCC(=O)N(Cc1ccccn1)C1CC1 +N#CCCCSc1nc(-c2ccc(Cl)cc2)n[nH]1 +Cc1ccc(-c2nnn(CC(=O)Nc3cccc(F)c3)n2)cc1 +COC(=O)CN(Cc1sccc1C)C1CCCC1 +COCCCNC(=O)N1CCC(C(=O)NC2CC2)CC1 +Cc1ccc(C#N)cc1NC(=O)NC1c2ccccc2CC1O +CC(NC(=O)CSc1nc(N)c2ccsc2n1)C1CC1 +N#Cc1c(-c2ccccc2OCCO)cc(C2CCCC2)nc1N +CCCS(=O)(=O)N(C)CC(=O)Nc1ccc(Cl)c(Cl)c1 +CCS(=O)(=O)c1ccccc1C(=O)N1CCCC2(CC=CCC2)C1 +Cc1cccc(OCCNC(=O)Cc2ccccc2F)c1 +Cc1ccc(NS(=O)(=O)c2ccc(-n3cccn3)cc2)cc1C +Cc1ccccc1C(=O)Nc1cnn(CCc2ccccc2)c1 +CC(C)N(C(=O)Cc1csc(N2CCCC2=O)n1)C1CCC1 +CC(C)(C#N)C(=O)Nc1cc2c(cc1Br)OCCO2 +Cc1cccc(OCC(O)CN2CCN(CCO)CC2)c1 +CC(=O)Nc1ccc(NS(=O)(=O)Cc2ccccc2F)cc1 +CCCCC(=O)Nc1ccc(OC)c(N2CCCC2=O)c1 +COc1cc(C(=O)N(C)CCCc2n[nH]c(N)c2C#N)ccc1Cl +Cc1c(C(=O)N(C)Cc2ccc3c(c2)OCO3)oc2c1C(=O)CCC2 +COc1ccccc1C(C#N)NC(=O)c1cccc(OCC(F)F)n1 +COCCS(=O)c1ccccc1S(N)(=O)=O +Nc1cc(C(=O)NCC2CCCCO2)ccc1Cl +CCCCn1ncc(NC(=O)c2ccc(-n3ccnn3)cc2)c1C +CC1(C)CNc2cc(S(=O)(=O)N3CCOCC3)ccc2O1 +COc1cccc(-c2noc(Cn3ncc4ccccc4c3=O)n2)c1 +Cc1nc2ccccc2n1CCCNC(=O)C(C)NC(N)=O +CC(C)Cn1c(CCNC(=O)c2ccncc2)nc2ccccc21 +Cn1cc(CCc2nc(CNC(=O)c3ccccc3)no2)cn1 +CC(C)C(NC(N)=O)C(=O)NCCNC(=O)c1ccccc1 +CN1CC(C(=O)NCc2cccc(CN3CCOCC3)c2)CC1=O +Cc1ccc(CN(C)C(=O)CSc2nc3ccccc3s2)o1 +O=C(Nc1ccc2c(c1)OCO2)C1CCN(C(=O)C2CCCC2)CC1 +Cc1ccc(C(C)NS(=O)(=O)c2ccccc2Cl)o1 +Cc1cc(C)c2c(OCC(=O)NC3CC3C)nn(C)c2n1 +Cc1cc(NC(=O)c2ccccc2NC(=O)c2ccsc2)n(C)n1 +CCN(Cc1cccs1)C(=O)c1sccc1C +CC(C)(C)c1noc(CCNS(=O)(=O)c2ccccc2F)n1 +Cc1ccc(-c2noc(CCC(=O)N3CCNC(=O)CC3)n2)cc1F +Fc1cccc(CNc2nnc(C3Cc4ccccc4O3)o2)c1 +COc1ccc(C(=O)c2noc3cc(C#N)c(C#N)cc23)cc1 +Cn1c(Sc2ncnc3sccc23)nnc1-c1ccco1 +CCOC(=O)c1cnc(Nc2ccc(Cl)cc2)nc1C +Cc1cc(CNS(=O)(=O)c2ccc(C)c(C(F)(F)F)c2)no1 +CC(=O)NCCNC(=O)CSc1cc(C)ccc1C +COc1ccc(NC(=O)C(CC(C)C)N2CCCCC2=O)cc1OC +CC(C#N)CN(C)C(=O)Nc1ccc(C(C)O)cc1 +COCCSc1nc2ncc3c(n2n1)CC(C)(C)CC3=O +COC(=O)CC(C)C(=O)c1cc(Cl)ccc1OC +O=C(Cn1cnc2cc(F)c(F)cc21)N(Cc1ccccc1)C1CC1 +CC(c1cccnc1)N(C)C(=O)NCC1CC=CCC1 +CC1COCCN1C(=O)CNC(=O)OC(C)(C)C +O=C(CN1CCn2c(nnc2-c2ccccc2)C1)NCc1cccnc1 +CN1C(=O)c2ccccc2N2Cc3ccccc3CC12 +COc1ccc(C(C)NC(=O)c2sc(C)cc2OC)c(OC)c1 +COc1ccc(-c2cc(-c3cc(C#N)n(C)c3C)c(C#N)c(N)n2)cn1 +CCOc1ccc(C(=O)Nc2ccc(OC)c(OC(F)F)c2)cc1 +CSc1cccc(-c2nnc(NC(=O)c3ccco3)o2)c1 +CCOC(=O)CNC(=O)c1ccc(-c2ccccc2)cc1 +NC(=O)CN(C(=O)C1Cc2cc(Cl)ccc2O1)C1CCCC1 +CSc1nc(C)c(CCOC(=O)c2ccccc2)c(=O)[nH]1 +Cc1ccc(CN(C)C(=O)COc2ccc3c(C)cc(=O)oc3c2)o1 +CCn1c(=O)[nH]c(=O)c2cc(C(=O)NC(C)(C)C(N)=O)cnc21 +NC(=O)NCCCOC(=O)c1coc2ccccc12 +COc1ccc(Nc2ncnc(N3CCN(CCO)CC3)c2N)cc1 +CCc1nn(C)c(CC)c1CNc1ccc2c(c1)CCCC(=O)N2 +COC(=O)N1CCCC1C(=O)Nc1nccs1 +Cc1ccc(C)c(NC(=O)CNC(=O)Cc2ccccc2)c1 +CCN(CC)c1ccc(C(=O)NC(C)c2csc(C(C)C)n2)cn1 +NC(=O)C1CCN(C(=O)NC2CCC(OCC(F)(F)F)CC2)C1 +COc1cc(OC)c(NC(=O)c2cnn(-c3ccccc3)c2)cc1F +COc1ccc(CC(=O)N2CC(=O)Nc3ccccc32)cc1OC +Cc1onc(-c2ccccc2Cl)c1C(=O)OCC(=O)NC(C)C +Cc1csc(NC(=O)C2CCCN(C(=O)OC(C)(C)C)C2)n1 +CCn1c(C)nnc1SCC(=O)NC1CCCC1 +COCCN(Cc1ccc(C#N)cc1)C(=O)c1cccc2c1OCO2 +CC(C)CCNC(=O)CNC(=O)c1cc(F)cc(F)c1 +COc1cnc(C2(C#N)CCC(=O)CC2)cc1OC1CCCC1 +CC(NC(=O)NCC(=O)OCc1ccccc1)c1ccc(F)c(F)c1 +Cc1cc(C(=O)NCC2(C)COC2)c2c(C)noc2n1 +CC(Cn1nnc2ccccc21)NC(=O)C1CCC1 +C=CCN(Cc1cccc(C#N)c1)C(=O)Cc1ccc[nH]1 +O=C(COCc1nc(-c2ccncc2)no1)NCc1cccnc1 +Cc1nn(C)c(=NS(=O)(=O)c2cc(Cl)c(N)c(Cl)c2)[nH]1 +Cc1cc(C)cc(NC(=O)COc2c(CO)cc(F)cc2CO)c1 +CCN(Cc1noc(CC(C)C)n1)C(=O)c1ccc2nccn2c1 +O=c1ccc2c([nH]1)CCN(Cc1cccs1)CC2 +CCOC(=O)CNC(=O)Cn1c(=O)[nH]c2ccccc21 +C=CCCOC(C)C(=O)Nc1cccc(C(=O)NC)c1 +COC(=O)CCNC(=O)Cc1noc2ccc(N)cc12 +COc1ccc(F)cc1NC(=O)Cn1cnc2ccccc2c1=O +COC(=O)c1cc2cc(F)c(Br)cc2cc1Cl +CCOC(=O)c1sc2ncnc(Oc3ccc(CO)cc3)c2c1C +CC1=C(C(=O)Nc2cccc(C)c2)C(c2ccco2)n2ncnc2N1 +C=CCSc1ccccc1NC(=O)c1cscn1 +CCCSc1nnc(NC(=O)c2ccc(-n3cnnn3)cc2)s1 +Cc1cc(CNc2ccccc2OC(F)(F)F)no1 +Nc1ccc(Cn2c(CO)nc3ccc(F)cc32)cn1 +CC1CN(CCNC(=O)c2cnccn2)CC(C)O1 +Cc1cccc(NC(=O)Cc2csc(-n3cccc3)n2)c1 +Cc1csc(CCNC(=O)c2cccc(CCC(C)(C)O)c2)n1 +COCc1ccc(C(=O)N2CCN(c3ccccc3O)CC2)cc1 +CC(C(=O)NCC1COc2ccccc2O1)N1CCOCC1 +Cc1cccc(C)c1NC(=O)c1cc(C)n(-c2ccccc2)n1 +CCc1ccc(C(C)NC(=O)NCC(=O)NC(C)(C)C)cc1 +Cc1ccc(C(=O)Nc2ccc3oc(=O)n(C)c3c2)cc1 +Cc1nc(-c2ccc(S(=O)(=O)N3CCCCCC3)cc2)co1 +CCCN1C(=O)C2(CCCCC2)NC1c1cn(C)c(=O)n(C)c1=O +CNC(=O)CSc1nc(C(C)C)nc2sc3c(c12)CCCC3 +COc1ccc2cc(NC(=O)c3ccccc3C)cnc2c1 +Cc1ccc(NC(=O)c2nc(C)n(-c3ccccc3C)n2)cc1 +CC(COc1ccccc1)NC(=O)c1ccnc(-n2ccnc2)c1 +O=C(c1n[nH]c2c1CN(Cc1ccccc1)C2)N1CCCC1 +CCCC(=O)N1CCCC1C(=O)c1cccs1 +O=C(CNC(=O)NC1CCCN(c2ccccc2F)C1=O)NC1CC1 +Cc1cccc(C(C(=O)NCCCC(=O)N(C)C)N(C)C)c1 +CN(Cc1ccsc1)C(=O)NC1CCc2ccccc21 +O=C(C1CCOC1)N1CCOC(c2ccc(C(F)(F)F)cc2)C1 +COCCCNC(=O)c1cn(C)nc1C(C)(C)C +CC(COc1ccccc1)NC(=O)c1ccc[nH]c1=O +Cc1cc(NC(=O)Cc2ccc(O)cc2)c2ncccc2c1 +CCOc1ccc(NC(=O)C(C)n2cc(N)ccc2=O)cc1 +COc1ccccc1-c1cc(NC(=O)CCCn2cncn2)[nH]n1 +O=C(Cn1cnc2ccsc2c1=O)Nc1ccc2c(c1)OCCO2 +COc1cc(C2Nc3ccccc3C(=O)N2C2CC2)ccc1O +Cc1nn(C(C)C)c(C)c1NC(=O)C(C)NC(N)=O +COC(=O)CC(C)NC(=O)c1cc(C)n(CC2CC2)c1C +Cn1nc2n(c1=O)CCN(CC(=O)NCc1ccccn1)C2 +Cc1ccc(O)c(NC(=O)c2ccc(C(F)(F)F)nc2C)c1 +CC1(C)CN(C(=O)C2CC(=O)N(c3cc(F)cc(F)c3)C2)CCO1 +Cc1ccc(S(=O)(=O)Nc2cccc(C(C)O)c2)cc1 +Cc1csc(=O)n1CC(=O)NC(c1nc2ccccc2[nH]1)C(C)C +CC(=O)c1ccccc1NC(=O)c1cnn(-c2ccc(F)cc2)n1 +Cc1cccc(O)c1NC(=O)CNC(=O)c1c(F)cccc1Cl +O=C(c1cccc(C(F)(F)F)c1)N1CCOCC1 +Cc1ccc(SCC(=O)N2CCCC(C)C2)cc1 +Cn1c(=O)ccn(CC(=O)N(Cc2ccco2)CC2CCCO2)c1=O +COc1ccc(S(=O)(=O)Nc2ccc(CC(N)=O)cc2)cc1C +COC(=O)C(C)N1CCN(C(=O)CCc2ccc(OC)cc2)CC1 +CNC(=O)NCC(=O)Nc1ccccc1OC(F)(F)F +CCOC(=O)c1c(-c2ccccc2)noc1C1CC1 +CCNC(=O)CN1CCN(S(=O)(=O)C(C)C)CC1 +Cc1csc(CNC(=O)Nc2ccccc2C(=O)NC(C)(C)C)n1 +CCCC(=O)Nc1ccc(C2(C(=O)NCC(C)C)CC2)cc1 +COC(=O)C1(Nc2cccc(Br)c2)CCOCC1 +CS(=O)(=O)Oc1ccc2c(-c3ccccc3)noc2c1 +NC(=O)c1ccc(C2CN(c3ncccn3)CCO2)nc1 +COCCOC(=O)c1cnc2sc(Cc3ccccc3)cn2c1=O +O=C(Nc1ccc(N2CCCC2=O)cc1)c1ccc(-n2cccc2)cc1 +NC(=O)c1ccccc1NC(=O)CCSc1ccccc1Cl +COc1ccc(CCCC(=O)N2CCOCC2)cc1N +Cn1c(=O)n(C)c2cc(NC(=O)CSc3ncn[nH]3)ccc21 +CCCN1C(=O)CCc2cc(NC(=O)c3ccccc3C)ccc21 +CCn1cc(CNc2cccc3ccccc23)cn1 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1ccc2ccccc2c1 +CC(C)Oc1ccc(C(=O)OCn2nnc3ccccc3c2=O)cc1 +N#CCCN(C(=O)CN1CCOCC1C1CC1)c1ccccc1 +CS(=O)(=O)NC1CCCN(C(=O)Cc2ccccc2)C1 +CC(C)(C(=O)NC1CCC(O)CC1)c1ccc(N)cc1 +COCC(C)NC(=O)CSc1nc(C2CC2)nc2ccccc12 +CC(C)Cc1nnc(NC(=O)CCC(=O)Nc2ccccc2)s1 +Cc1cccc(OCCNC(=O)Nc2cc(C)on2)c1 +CCC(NC(=O)NCCCOC)c1ccc(Cl)cc1 +O=C(Nc1cc(Cl)ccc1Cl)N1CCCC2(C1)OCCO2 +Cc1ccc(CNC(=O)NCCOc2ccc(F)cc2F)cn1 +CNC(=O)C1CN(C(=O)c2ccc(Cl)cc2F)c2ccccc2O1 +CN(c1ccccc1)c1ccccc1C(=O)NCCCO +Cc1nc(C(N)Cc2cccs2)sc1C(C)C +CC(C)c1ccc(NC(=O)CCC(=O)c2cccc(N)c2)cc1 +COc1cccc(CSc2nnc(-c3cnccn3)n2C)c1 +CNC(=O)c1ccc(CN(C(=O)c2cc(F)cc(F)c2)C2CC2)cc1 +COc1ccc(CN(C)C(=O)c2ccc(NC(C)=O)cc2)cc1F +Cc1ccc(C(=O)c2c[nH]c(C(=O)NCc3cccnc3)c2)cc1 +CCc1noc(C)c1C(=O)Nc1ccc(Oc2cccnc2)c(C)c1 +CC(C)(C)C(NC(=O)Nc1ccc(C#N)c(C(F)(F)F)c1)C(N)=O +N#Cc1c(Cl)cc(C(=O)N2CCCCC2)cc1Cl +CCC#CCN1CCN(c2ncnc3[nH]ccc23)CC(O)C1 +CN(CC(=O)NCCc1nc2ccccc2n1C)S(C)(=O)=O +C#CCOc1ccc(C(=O)NC(C)CCCO)cc1 +CCOc1ccc(-c2csc(NC(=O)c3cnc(C)cn3)n2)cc1 +O=C(NC1CCCCCC1)C1CC2CCCC(C1)C2=O +Nc1cc(N)nc(SCC(=O)c2ccc3c(c2)CCC3)n1 +CCCn1nnnc1CSc1nnnn1-c1ccc(O)cc1 +COc1ccc(NC(=O)c2cc(C(N)=O)cn2C)cc1OC +CCN(C(=O)Cn1cnc2c(cnn2C)c1=O)c1ccccc1 +CNC(=O)c1c(C)cccc1NC(=O)C1CC2C=CC1C2 +Cc1nc(CN(C)C(=O)Nc2nc(CC(C)(C)C)cs2)no1 +COc1ccc(-c2c(C)n[nH]c2NC(=O)CC(C)C)cc1OC +Nc1c(-c2ccccc2)noc1C(=O)NCc1ccco1 +CCSc1nc(C)cc(C(=O)NC(C)(C)C)n1 +C=CCOc1cccc(C2Nc3ccccc3C(=O)N2C)c1 +CC(C)c1cc(C(=O)Nc2ccc3c(c2)COC3)nn1C +NS(=O)(=O)c1cccc(CNC(=O)NCCC2CCCCC2)c1 +CCc1noc(C(C)S(=O)c2ccccc2S(C)(=O)=O)n1 +O=C(NCCCc1nc2ccccc2[nH]1)Nc1ccc2c(c1)COC2 +O=C1NCCN1c1cccc(NCc2cc(Cl)ccc2F)c1 +COc1ccc(C(=O)OCC(=O)Nc2ccc(F)c(F)c2)c(F)c1 +CCNC(=O)COc1ccc(NC(=O)N(C)C(C)c2ccco2)cc1 +CCC(C)(C#N)NC(=O)C(C)Oc1ccc(SC)cc1 +Cc1cc(C)n(CC(C)CNC(=O)NC2CC2)n1 +COCc1cccc(CNS(=O)(=O)c2ccc(C(C)=O)cc2)c1 +CC(=O)c1ccc(NC(=O)Cc2ccc(F)cc2)cc1C +COc1ccc(Cl)c2c1N(C(=O)C(C)c1c(C)noc1C)CCC2 +C#Cc1cccc(NCC(=O)Nc2ccc(C)cc2)c1 +CN(CCc1ccc(F)cc1)Cc1ccc(C(=O)N(C)C)[nH]1 +Cc1ccc(C(CNC(C)c2ccncc2)N2CCOCC2)s1 +O=C(CSc1ccc(-n2ccnc2)nn1)N1CCCC1 +COC(=O)CC1CCCCN1C(=O)c1cccc(Cl)c1Cl +NC(c1ccccc1)c1nc2cc(O)ccc2n1CCO +COc1ccc(CCC(=O)Nc2nc(C(C)=O)cs2)cc1OC +COc1cc(C=Cc2nc3ccccc3c(=O)n2C)ccc1O +CCOC(=O)NCCC(=O)NCc1cc2ccccc2[nH]1 +CCC(=O)Nc1ccc(C(=O)COC(=O)c2ccccn2)cc1 +O=C(CCCC(=O)c1ccc(F)c(F)c1)NCC1CCCO1 +Cc1csc(-c2cnn(-c3ccccc3)c2N)n1 +O=C(NC1CCCC1)c1ccc(Cn2cccn2)cc1 +Cc1nc(CNC(=O)CCC2Cc3ccccc3NC2=O)c(C)s1 +COc1ccc(NC(C)=O)c(NC(=O)c2ccc(CC(C)C)cc2)c1 +O=C(c1ccc(Cl)cc1)N1CCCC(Cc2nccs2)C1 +NC(=O)Nc1ccc(NC(=O)CCc2ccccc2O)cc1 +CC1CN(C(=O)Nc2ccc3ccccc3c2)CCO1 +CCN(CC1CCCO1)C(=O)c1cc(C(C)C)[nH]n1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccc(CC#N)cc1 +CCCC(=O)Nc1ccc(N2CCCC2=O)c(OC)c1 +Cc1ccc(NC(=O)N(C)Cc2ccc3c(c2)OCO3)cc1 +O=C(COc1cccc(-n2cnnn2)c1)NCC(F)(F)F +Cc1ccc(C(=O)Nc2ccccc2)cc1NC(=O)NCc1ccco1 +CC1CCN(C(=O)c2ccc(-n3cnnn3)cc2)CC1 +CC(C)C(NC(=O)Cn1nnc2ccccc2c1=O)c1cccs1 +COc1ccc(C)cc1-n1cnnc1-c1cn[nH]c1 +CC(C)(CNC(=O)NCCc1ccc2c(c1)OCO2)N1CCOCC1 +Cn1ncc2c(NCc3ccn(-c4ccccc4)n3)ncnc21 +O=C(Nc1ccccc1-n1cccn1)N1CCCC(c2nc[nH]n2)C1 +COc1ccc(CNC(=O)Nc2cccc(Cl)c2C)cn1 +Clc1ccc(CNc2nncs2)cc1Cl +COCCOc1ccc(NC(=O)NC2CCOc3ccccc32)cn1 +COc1ccc(-c2ccc3nc(CO)[nH]c3c2)cc1Cl +Cc1nnc(NC(=O)CNc2ccccc2OC(C)C)s1 +COCCC(=O)Nc1cnn(-c2ncncc2N2CCC(C)CC2)c1 +COc1ccc(C(O)CNc2ccccc2Cl)cc1 +COCCn1cc2c(n1)C(NC(=O)Nc1ccncc1)CCC2 +CCn1cnnc1CNC(=O)Cc1cccc(F)c1F +O=C(NCC(C1CC1)C1CC1)c1cccc(C2OCCO2)c1 +CN(C(=O)c1cnn(C(C)(C)C)c1)C(CO)C(C)(C)C +Cc1ccc(F)c(S(=O)(=O)N2CCOCC2(C)C)c1 +COCCC(=O)NC1CC(=O)N(CCc2ccccc2)C1 +O=C(Nc1ncc(Cc2ccc(F)c(F)c2)s1)C1COCCO1 +O=C(NCc1ccc(OC2CCCC2)nc1)Nc1ccccc1 +COc1ncccc1NC(=O)N(CCC(N)=O)Cc1ccccc1 +Cc1ccc(C)c(COC(=O)Cn2ccc(N)n2)c1 +COc1ccc(S(N)(=O)=O)cc1C(=O)OC(C)C(=O)NC1CC1 +Cc1nc2ccccc2cc1C(=O)NC(C)C(=O)N1CCCCC1 +CC(=O)NC1CN(C(=O)CCc2ccccn2)CC1c1ccc(C)o1 +COc1cc(CCc2nnc(-c3cccs3)o2)cc(OC)c1OC +C#CCCCCC(=O)Nc1ccc(C(=O)NC)cc1Cl +Cc1cc(N)c2onc(CC(=O)Nc3c(C)cccc3C)c2c1 +O=C(CC1C=CCC1)N1CCC(OC2CCOC2)CC1 +CC(Sc1nnc(SCC(N)=O)s1)c1ccccc1Cl +Cc1n[nH]c(C)c1CNC(=O)c1cccc(NCc2cccs2)c1 +Cc1nn(-c2ccccc2)c(C)c1CCC(=O)NCC1CC1 +CCN(CC(O)c1ccc(C)cc1)C(=O)c1cc(C)c(F)cc1F +CCOC(=O)c1sc(NC(=O)c2cnc(C)cn2)cc1C +O=C(c1ccc(Cl)cc1)N1CCCC1c1nc2ccccc2[nH]1 +CCCCc1noc(C2CCCCN2C(=O)CCc2cnn(C)c2)n1 +CCCNC(=O)CNc1cccc(C(=O)NC)c1C +NC(=O)c1cn[nH]c1C1CCCN1C(=O)COc1ccccc1 +CC(O)c1cn(C2CN(C(=O)CC3CCC(C)(C)CC3)C2)nn1 +CCc1ccc(CCC(=O)Oc2cnn(C)c2)cc1 +Cc1ccc(-c2cc(C(=O)N3CCCC3)ccn2)s1 +CCC1CCC(C(=O)NCc2nc(C3CC3)n[nH]2)CC1 +O=C(CSc1ncnc2nc[nH]c12)c1ccccc1 +Cc1c(NCc2ccnn2C2CCCC2)cnn1C +CCCCS(=O)(=O)N1CCCC1C(=O)Nc1ccccc1C +COC(=O)c1nnn(CC(=O)Nc2ccc(C)c(C)c2)c1C(=O)OC +COc1ccccc1CNc1cccc(C(C)=O)c1 +Cc1ccccc1OC1CN(C(=O)c2cc(C3CC3)n[nH]2)C1 +O=C(CSc1nnc(-c2ccccc2)o1)Nc1ccncc1 +CC(=O)c1ccc(C2NCCc3ccc(F)cc32)s1 +N#Cc1ccc(NCC(=O)N2CCN(c3ccccc3)CC2)cc1 +N#Cc1nn(-c2nc3ccccc3s2)c2c1C(=O)CCC2 +CN(c1ccccc1)c1ccccc1NC(=O)NCCC1CCCO1 +CCN(CC)C(=O)CSc1ccc(-c2ccc3c(c2)OCO3)nn1 +Nc1ccc2c(c1)N(C(=O)c1ccc3c(c1)CCC3)CC2 +Cc1cccc(CCNC(=O)c2cccc3c2OC(C)C(=O)N3)c1 +COc1ccccc1C1CCN(C(=O)c2cc(C)c(C)[nH]c2=O)CC1 +COc1ccc(C(C)(C)C)cc1-c1cc(=O)[nH]c(N)n1 +CS(=O)(=O)c1ccc(N2CCC(O)CC2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)c1cnn(-c2ccccc2)c1 +CC(=O)c1ccc(NCc2nc(C3CC3)no2)cc1 +COc1cccc(OC)c1-c1nc2cc(N)ccc2o1 +CC(C)(C)c1ccc(C(=O)NCCNc2cnccn2)cc1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)NCc3cscn3)c12 +O=C(Cc1cccc(F)c1)NCCNC(=O)c1ccco1 +CCCCNC(=O)C1CCCN(c2cn[nH]c(=O)c2)C1 +C=CCN(Cc1cccs1)C(=O)NCc1csc(C)n1 +c1cncc(CSc2cccc3cccnc23)c1 +CC(C)n1[nH]c(=O)c2c1N=C(O)CC2C1CCCCC1 +Nc1cccc2c1OCC(=O)N2CCOc1ccccc1 +NC(=O)CC1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +CCOCCCNC(=O)C1CCCN(c2ncccn2)C1 +Cc1ccncc1NC(=O)N1CCc2ccccc2C1 +COC1CCCC1OC(=O)Cn1c(=O)[nH]c2ccccc2c1=O +O=C(NCc1nncn1C1CC1)Nc1ccc(C(F)(F)F)cc1 +COc1ccc(OCCCC(C#N)C(=O)N2CCCC2)cc1 +CCCn1c(C)cc(-c2csc(NC(=O)c3cccnc3)n2)c1C +CCC(C)NC(=O)NCCOc1cccc(F)c1 +Cc1cc(OCC(=O)NCCCO)c2c3c(c(=O)oc2c1)CCCC3 +Cc1cc(NC(=O)C(C)OC(=O)c2ccc3c(c2)OCCO3)no1 +O=C(OCC1CCCCO1)c1ccc2ccccc2n1 +CCCNc1ccccc1C(=O)N1CCC(O)CC1 +O=C(NCCn1ccnn1)Nc1c(F)cc(F)cc1-c1ccccc1 +Cc1nnc(C2CCN(Cc3ccccc3Cl)C2)o1 +C=CCOc1cccc(CN(CC)C(=O)C2CCCN2C(N)=O)c1 +COc1cc(N)c(NC(=O)c2ccc(Cl)c(Cl)c2)cc1OC +O=C(NCc1ccccn1)c1ccc(-c2cscn2)cc1 +Cc1ccc(C(=O)Nc2ccccc2N2CCCCC2)o1 +Oc1cccc(C2NCCc3cc(F)c(F)c(F)c32)c1 +CCc1onc(C)c1NC(=O)c1cccc(OCc2noc(C)n2)c1 +CC1CN(c2ccccc2)CCN1Cc1ccc(C#N)cc1 +c1ccc2c(c1)CCNC2c1ccc2ncccc2c1 +O=C(NCc1[nH]ncc1Br)Nc1ccc(F)cc1F +C=CCn1c(N)nnc1SCC(=O)N1CCc2ccccc21 +Nc1ccc(S(=O)(=O)NCCc2ccc3c(c2)OCCO3)cc1 +CC(C)(C)CCOC(=O)Cn1ncc(=O)c2ccccc21 +CCN(Cc1cccc(F)c1)C(=O)COc1ccc(C(C)=O)cc1 +C=CCn1c(C)nnc1SCC(=O)NCC(C)C +O=C(NCCOc1ncccc1Cl)N1CCOCC1C1CC1 +CC1Cc2cc(S(=O)(=O)Nc3cn[nH]c3)cc(Cl)c2O1 +CC(C)(C)n1ncc2c(=O)n(NC(=O)C3CCCO3)cnc21 +CCCOc1ccc(CNC(=O)c2ccc[nH]c2=O)cc1 +O=C1CN(C(=O)COc2ccccn2)c2ccccc2N1 +CC(Oc1cc2c(cc1N)OCCO2)c1ccccc1 +Cc1[nH]nc(-c2ccc3c(c2)ncn3C2CC2)c1N +O=C(NCc1ccoc1)c1ccc(-n2ccnc2)nc1 +N#Cc1cccc(C(=O)Nc2ccc3[nH]ncc3c2)c1 +CCCNC(=O)C1CCCN(C(=O)NCCN2CCOCC2)C1 +CCc1onc(C)c1NC(=O)NC1CCN(c2ccccc2F)C1=O +CN(Cc1ccnn1C)C(=O)C1(C)Sc2ccccc2NC1=O +CC(NC(=O)c1cnn2cccnc12)c1ccc2c(c1)OCCCO2 +O=C(c1ccc(-c2ccco2)[nH]c1=O)N1CCc2ccc(F)cc21 +O=C(NCC1CCN(C(=O)c2ccccc2F)CC1)c1ccccc1 +CCOC(=O)c1noc2ncnc(NCc3cccc(OC)c3)c12 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCN(C)c2ccccc2C1 +Cc1ccc2c(c1F)C(c1ccc(O)cc1F)NCC2 +N#Cc1ccc(C(N)c2nnc(C3CC(=O)C3)o2)cc1 +O=C(Nc1cccnc1)C1CCCN(C(=O)c2cccs2)C1 +COCc1ccc(-c2nc(-c3ccncc3)no2)cc1 +Cc1cc(C(=O)NCC(C)(C)N2CCOCC2)[nH]n1 +CCC1c2ccsc2CCN1C(=O)CCc1nc(C)no1 +C#CCN1CCN(Cc2cc(C(=O)OC)oc2CC)CC1 +COc1c(NC(=O)Nc2cc(C)cc3cccnc23)c(C)nn1C +Cn1cnnc1SCc1csc(-c2ccccn2)n1 +CCOC(=O)Nc1ccc(NC(=O)NC(C)CC)cc1 +CC1CCCN(C(=O)c2ccc3ccccc3c2O)C1 +COc1ccc(CC(=O)N2CCOCC2c2cccn2C)cc1F +O=C(c1ccc(NCc2nc(C3CC3)no2)cc1)N1CCCC1 +O=c1c(NCC2CCCO2)csc2ccccc12 +Cc1noc(C)c1C(C)NC(=O)NC(C)c1csc(C2CC2)n1 +COc1ccc(CCCCC(=O)N2CCOC(C(N)=O)C2)cc1 +O=C(CCC1CCCC1)OCC(=O)c1ccc2c(c1)OCO2 +O=C(c1cccs1)N1CCn2c(Cn3cccn3)cnc2C1 +O=C(NCCNC(=O)c1ccccc1)Nc1ccc(OC(F)F)cc1 +CC(=O)NCCNS(=O)(=O)c1cccc(F)c1 +CC(COCC(F)(F)F)NC(=O)c1ccc(-c2ccco2)[nH]c1=O +COCC1CCN(c2ccnc(-c3ccccc3)n2)CC1 +Cc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)cc1C +CCC(C)C(C)NC(=O)Cc1noc2ccccc12 +CC(Sc1ccccn1)C(=O)NCCC(O)c1ccccc1 +COCC(=O)NC(C)c1ccc(Cl)cc1Cl +CN1CCC(NC(=O)N(C)C2c3ccccc3-c3ccccc32)C1=O +NC(=O)c1ccccc1NC(=O)Nc1cc(F)ccc1F +NC(=O)c1ccc(CSc2nnnn2C2CCOCC2)cc1 +Cc1ccccc1NC(=O)c1ccc(NC(=O)c2ccco2)cc1 +COc1ccc(CCC(=O)c2cccnc2)cc1Br +COC(=O)CN1CCc2cccc(C(=O)OC)c2C1 +COc1ccc(COc2ccc(C#N)cc2OC)cc1 +C=CCn1c(C)cc(C(=O)Cn2c(CO)nc3ccccc32)c1C +COc1ccccc1NC(=O)c1ccc(N2CCCCC2=O)cc1 +CC1Sc2ccc(C(=O)N3CCC4(CC3)OCCO4)cc2NC1=O +CC(C)CCN(C)C(=O)c1cc(C(N)=O)cs1 +O=C(NCCn1ccc2ccc(Cl)cc21)c1cccnc1 +CC(NC(=O)c1cccc(-c2ccoc2)c1)c1ccncc1 +CC1CN(C(=O)c2cnccn2)c2ccccc2S1 +COc1ccc(-n2cccn2)c(CN(C)Cc2nncn2C(C)C)c1 +CCOC(=O)c1sc(C2CCC(=O)N2)nc1C(F)(F)F +O=C(COc1ccccc1)NCC(O)c1ccc2c(c1)CCC2 +Cc1ccnc(N2CCc3onc(-c4ccccc4F)c3C2)n1 +CC(C)C(C)NC(=O)Cn1cnc2ccc(F)cc2c1=O +CCC(C)C(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2C)CC1 +CCCCNC(=O)CN1CCN(C(=O)OCC)CC1 +CN(C(=O)NCc1ccnc(OC2CCC2)c1)C1CCC(CO)CC1 +COC(=O)C1=C(C)N(C)C(=O)CC1c1ccc2c(c1)OCO2 +Cc1noc2nc(C3CC3)cc(C(=O)OC(C)C)c12 +N#Cc1c(-c2ccccc2F)nn(-c2ccccn2)c1N +Cc1nccnc1N1CCn2nc(CNC(=O)N(C)C)cc2C1 +O=C(CC(F)(F)F)NCc1noc(-c2ccc(F)cc2)n1 +O=C(CC1CCCCC1)NCc1nncn1-c1ccccc1 +Nc1nonc1C(=O)NCc1cccc2c1OCO2 +O=S(=O)(CC1CCCCC1)NCCOc1ccc2c(c1)OCO2 +CCOc1ccccc1NC(=O)c1nccc2c(N)cc(F)cc12 +COc1ccc(-n2ccc(CNC(=O)c3cc(C)sc3C)n2)cc1 +CCC(C)C(=O)COc1nnc(-c2ccccc2)o1 +Cc1cccc(N(C)S(=O)(=O)c2cccc(C(=O)N(C)C)c2)c1C +Cc1cc(C)n(S(=O)(=O)c2ccc(F)c(C)c2)n1 +Cc1ccc(CNC(=O)c2ccc3nc(C)c(C)nc3c2)o1 +Cc1cc(NC(=O)C(Oc2ccc(C#N)cc2)c2ccccc2)no1 +Cn1cc(C(=O)Nc2ccc(CCN3CCOCC3)cc2)ccc1=O +CC(C)(C)OC(=O)N1CC(COC2CCC2=O)C1 +CCOc1ncccc1-c1cc(N2CCCC2)nc(N)n1 +CS(=O)(=O)NCCN1CCN(C(=O)Cc2ccccc2F)CC1 +Cc1ccccc1CN(C)C(=O)C1CCN(C(=O)OC(C)(C)C)C1 +COCC(=O)N1C2CCC(C2)C1COc1ccc(OC)cc1 +O=C(CCCOc1ccc(F)cc1)NC1CCCc2[nH]c(=O)ccc21 +Cc1cc(C(=O)NCc2cc(Br)ccc2F)on1 +Cc1ccccc1CCNC(=O)c1ccn(C)c(=O)c1 +Cc1ccc(NC(=O)COc2ccc(-c3nnco3)cc2)cc1F +Cc1nnc2sc(-c3cc(CC(C)C)n[nH]3)nn12 +O=C(C1CCCN(c2ncccn2)C1)N1CCCC(n2cncn2)C1 +O=C(c1cc(-c2cccnc2)on1)N1CCc2sccc2C1 +CCOC1CCCN(C(=O)NCc2cccc(OC(C#N)CC)c2)C1 +Cc1ccc(NC(=O)C2CC(=O)n3cnnc3N2)cc1Cl +C#CCNC(=O)c1ccc(C)c(NS(C)(=O)=O)c1 +CCNC(=O)CN(CC)C(=O)c1cc2ccccc2oc1=O +COC(=O)c1ccc(Cl)c(NCC2CCOCC2)c1 +O=C(NCc1cccnc1)NCc1ccc(OCC(F)(F)F)nc1 +CCC(=O)N1CCc2cc(C(=O)NCc3ccccc3C)ccc21 +CCSc1ncc2c(=O)n(CC(=O)NC(C)CC)cnc2n1 +Cc1cc(OCC(=O)NCc2ccccn2)c(C)cc1Br +COC(=O)C1Cc2ccccc2N1C(=O)c1ccnc2ccccc12 +c1cc(-n2c(C3CC3)nc3cc4c(cc32)OCCO4)ccn1 +CSc1cc(C(=O)Nc2ccccc2C(=O)NCC(C)C)ccn1 +CN(C)C(=O)c1cccc(S(=O)(=O)N2CCCCCC2)c1 +CCN(CC)C(=O)Nc1ccccc1N1CCCC1=O +Cc1ccccc1CCNC(=O)Cc1ccc(-n2cnnn2)cc1 +CCOC(=O)CNC(=O)NCc1csc(C)n1 +CC1CC(=O)Nc2ccccc2N1Cc1nc(C2CC2)no1 +Cn1nnc2cc(C(=O)Nc3nccs3)ccc21 +Cc1nc2c(NC3CCN(C(=O)C4CCCO4)CC3)cccn2n1 +CCn1ccc2cc(NC(=O)c3cccc(N4CCNC4=O)c3)ccc21 +COc1cc(NC(C)c2cccc(C)c2)ccc1NC(C)=O +CCN1CCN(C(=O)COc2ccc(F)cc2Cl)CC1 +COc1nc2ccccc2cc1-c1cnc(N)c(C)c1 +CCC(C)N(C(=O)c1csc(-c2cnccn2)n1)C(C)CC +CC1CC(=O)Nc2cc(-c3ccccc3)ccc2O1 +Cc1nn(CC(C)C)c(C)c1CC(=O)Oc1ccccc1F +CCCCC(O)c1cc(CC)cc2c1OCCC2NC(C)=O +CC(C)CC(C)(NS(=O)(=O)c1ccccc1)C(N)=O +COc1ccccc1Oc1ccc(NC(=O)C2CCOCC2)cc1 +C=CCNC(=O)N1CCC(c2nnc3n2CCC3)CC1 +COc1ccc(OCCn2c(=O)oc(=O)c3cccc(C)c32)cc1 +COc1ccc(OC)c(-c2csc(NC(=O)c3ccc[nH]3)n2)c1 +COCCNc1cc(-c2cccc(-n3cnnc3)c2)c2cc[nH]c2n1 +Cc1ccoc1C(=O)N1CCCC(c2nncn2C)C1 +COc1cccc(NC(=O)c2ccccc2N(C)S(C)(=O)=O)c1 +NC(C(=O)NCCO)c1cc(Cl)ccc1Cl +COC1COC2(CCN(C(=O)Cc3ccccn3)C2)C1 +COCCCn1c(=O)n(C)c(=O)c2c1nc(N)n2C +O=C(Cn1ncc2ccccc2c1=O)Nc1ccc(F)c(Cl)c1 +C=CCOc1cccc(NC(=O)NCc2ccncc2)c1 +CC(C)CNC(=O)c1ccc(NC(=O)c2cnccn2)cc1 +CC(C)(C)C(=O)NCC(=O)N1CCN(Cc2ccccn2)CC1 +O=C1OCCCN1CCn1cc(Cn2c(=O)oc3ccccc32)nn1 +CN(C(=O)CCNC(=O)C12CC3CC(CC(C3)C1)C2)c1ccccc1 +CC1CN(C(C)CNC(=O)c2cnc3ccccn3c2=O)CC(C)O1 +COc1cccc(CNC(=O)COc2cccc(C(=O)N(C)C)c2)c1 +CCOC(=O)c1c(C)noc1-c1ccc(C)cc1O +CCNC(=O)N(CC)C(C)c1cccc(OC)c1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1cc(F)cc2[nH]cnc12 +C#CCNC(=O)Nc1cc(-c2ccccc2C)nn1C +CSc1cccc(NC(=O)c2ccc(N)c(F)c2)c1 +CCOC(=O)C(NC)c1c(F)ccc2cn(C)nc12 +CCOc1cc(C)c(S(=O)(=O)NCC(C)C)cc1C +COC(=O)C(C)NC(=O)CSc1nccn1-c1cc(C)cc(C)c1 +COc1ccccc1C1(O)CCCN(C(=O)C2(C)CCCO2)C1 +CC(C)(NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1)C(N)=O +CCCCNC(=O)c1nn(-c2ccccc2)c2c1COC2 +N#CCn1c(=O)c(-c2ccccc2)nc2ccc(N)cc21 +Cc1nc2sccc2c(=O)n1NC(=O)CCOCc1ccccc1 +COc1cc(OC)c(NC(=O)NCCc2ncc(C)s2)cc1F +CC(C)(C)c1ncc(CN2CCCCC2CN2CCOCC2)s1 +COc1cc(C(=O)N2CCCC2c2cc(C)on2)cc2c1OCCO2 +CNc1nc(CNC(=O)Nc2cccc(-n3ccc(C)n3)c2)cs1 +CCN(CC1CC1)C(=O)CNC(=O)Nc1cccc(C)c1 +O=C(CNC(=O)C1CCCCC1)Nc1cccc(F)c1 +Cc1nc(-c2cccs2)sc1C(=O)N1CCNC(=O)CC1 +COc1ccc(CCC(=O)N2CC3(COC(C)(C)OC3)C2)cc1 +COc1ccc2cc(C(=O)NCC#CCOc3cccnc3)[nH]c2c1 +CCCNC(=O)C(C)NC(=O)c1ccc(NC(=O)C2CC2)cc1 +O=C(NCCCc1ccccc1)NCc1cc(=O)[nH]c2ccccc12 +COc1ccc(OC)c(-c2nn3cc(N)nc3s2)c1 +COC(=O)c1ccc2c(c1)N(C(=O)OC(C)(C)C)CC2 +Cc1oc(-c2ccsc2)nc1Cn1ccccc1=O +CCCOc1ccccc1NC(=O)c1[nH]nc(C)c1Br +CN(CCNC(=O)N1CCC(N2CCCC2=O)CC1)c1ccccc1 +CC(C)C(=O)NCCNC(=O)c1ccc(Br)c(F)c1 +CC1CCCN(S(=O)(=O)NCc2ccc(C(N)=O)cc2)C1 +Cc1cccc(C2NC(=O)NC3=C2C(=O)N(C)C3)c1 +C=CCN(C(=O)c1ccc(C)[nH]c1=O)C1CCc2ccccc21 +COCCC(=O)c1ccc(OC(C)C)c(Cl)c1 +Cc1ccc(-c2nnn(CC(=O)Nc3cccc(C)c3)n2)cc1 +N#Cc1cccc(-n2cnc3cc4c(cc32)OCCO4)c1 +CCc1cn[nH]c1C1CCCN(C(=O)c2ncoc2CC)C1 +O=C1CC(c2ccc3c(c2)OCO3)c2c(c3ccccc3[nH]c2=O)O1 +N#Cc1cccnc1OCc1ccc2c(c1)OCO2 +CCNC(=O)CN(CC)C(=O)NCc1cccc(N2CCCC2=O)c1 +CCN(Cc1ccc(OC)cc1)C(=O)Nc1ccc(NC(C)=O)cc1 +Cc1c(C(=O)OCc2ccccc2)nnn1-c1ccccc1 +O=C(NCCO)c1ccccc1OCc1ccc(Cl)cc1 +N#Cc1cccc(C(=O)Nc2nnc(Cc3ccccc3)s2)c1 +CCCNC(=O)CNC(=O)N(C)Cc1cnn(-c2ccccc2)c1 +CN(Cc1ccccc1F)C(C(N)=O)c1ccc(F)cc1 +O=c1oc(=O)n(CCOc2ccccc2)c2ccccc12 +CNC(=O)c1ccc(OC)c(NC(=O)Nc2ccccn2)c1 +CC(O)CNC(=O)c1ccc(S(=O)(=O)NCc2ccco2)cc1 +COc1ccc(C(C)(C)c2nc(-c3ccc(C#N)cn3)no2)cc1 +CC(C)N(C)C(=O)C1CCN(C(=O)NC2CCCC2)CC1 +Cc1noc(CSc2nncn2-c2cccc(Cl)c2)n1 +CNC(=O)CN1c2ccc(C)cc2-c2ccccc2S1(=O)=O +Cc1cc(Br)cc2c1CCNC2c1cc[nH]c1 +CCS(=O)(=O)N1CCC2(CCN(C(=O)c3cccnc3)C2)CC1 +Cc1cc(OCCN2C(=O)CCS2(=O)=O)ccc1Cl +COCCc1nc(C(C)n2cncn2)n(-c2ccccc2OC)n1 +CNc1cc(OC2CC2)ccc1NS(C)(=O)=O +CC1COCCN1C(=O)c1nc(N2CCOCC2)ncc1Cl +O=C(c1ccccn1)N1CC2CCCC2(COc2ccccn2)C1 +CC(=O)c1c[nH]c(C(=O)N2CCN(C(C)=O)CC2)c1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccccc2C#N)cc1 +Cc1nc(C)c(C(=O)Nc2ccc(-c3ccccc3)nn2)o1 +CCn1nc(C(=O)Nc2nc3c(s2)Cc2ccccc2-3)cc1C +COC(=O)c1cc(CN2CC(Oc3ccccc3OC)C2)ccc1O +Cc1ccc(C(=O)N2CCCC(CCc3ccc(F)cc3)C2)c(=O)[nH]1 +CCc1c(COC)nc(N2CCN(c3ccccc3F)CC2)[nH]c1=O +CC(C)OCCC1CCCCN1C(=O)NCCN1CCOCC1 +CC(C)CCNC(=O)NCc1cn(-c2ccccc2)nn1 +CCOc1cc(CNC(=O)C2CC2c2ccccc2)ccc1OC +COc1ccccc1CC(=O)N1CCC(NC(=O)NC(C)C)CC1 +O=C(Cn1ccccc1=O)Nc1nnc(C2CC2)s1 +Cc1nnc(SCC(=O)Nc2ccccc2C(F)(F)F)[nH]1 +CCOc1cc(Br)c2nc(NCCOC)sc2c1 +C=CCN(CC=C)C(=O)NC1CCOc2c(Cl)cccc21 +CN1CCOC2CN(C(=O)c3cccc(-c4ccoc4)c3)CC21 +COc1cccc(C(=O)COC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 +O=C(Cc1ccc(O)cc1)Nc1ccn(-c2ncccc2Cl)n1 +Cc1nnc(C(C)Sc2nnc(-c3cccc(Cl)c3)n2N)o1 +C#CCNC(=O)c1ccc(=O)n(Cc2nc(C)c3ccccc3n2)c1 +Cc1ccc(C(=O)NCC(=O)NCCN2CCOCC2)cc1C +OCc1ccc(C2NCCc3ccc(Cl)cc32)cc1 +O=C(NCc1cccs1)C1COC2CN(c3ncc(F)cn3)CC21 +O=C(Nc1nc(-c2cccnc2)cs1)C1(c2ccccc2)CCC1 +Cn1cc(CNC(=O)c2ccc(Cl)c(Cl)c2)cn1 +COC(=O)c1cc(-c2cc(C)c(C)cc2OC)[nH]c1N +CCCOc1cccc(C(=O)N(C)Cc2cccc(F)c2)c1 +NC1=NC(=O)C(Cc2cccc(Cl)c2)(c2cccc(Cl)c2)N1 +CN(C)C(=O)CCNC(=O)c1ccc(CSc2ccccc2)cc1 +COCCN1CCN(C(=O)c2cc(C)c(C)s2)CC1=O +Cc1cccc(CNC(=O)c2nc3ncc(Br)cn3n2)n1 +CCC(CC)C(=O)N1CCCC1C(=O)NCCc1csc(C)n1 +Cc1cc(C)cc(NC(=O)CSc2ncnc(N)n2)c1 +CCNC(=O)c1ccc(CNC(=O)NCCc2cccc(F)c2)cc1 +CC(C)N(Cc1nc(-c2cccs2)no1)C(=O)C(C)(C)C +Cc1ncsc1CN1CC2COCC2(COCc2ccncc2)C1 +CCOC(=O)c1cc2c(=O)n(C)c(=O)n(C)c2nc1C +COC(=O)c1cc(Cn2cnc3sc(C)cc3c2=O)oc1C +Cc1cccc2cnn(CCC(=O)NCC(=O)N3CCOCC3)c12 +COCC(O)c1cc(Br)cc2c1NC(=O)C2C +CS(=O)(=O)c1noc(-c2ccc(Cl)cc2)c1C#N +Cc1nc(CNC(=O)CSc2ccccc2)cs1 +Cc1ccc(C)c(OCn2ccc(C(=O)NCC3CCC3)n2)c1 +CCOCC(=O)N1CCC(n2c(-c3ccco3)nc3cccnc32)C1 +CCC(=O)Nc1ccc(Cl)c(C(=O)OC(C)C)c1 +O=C(NCc1ccccn1)c1ccc(-c2ncc[nH]2)s1 +COc1cccc(CNC(=O)CNc2cccc(NC(C)=O)c2)c1 +Cc1cc(C)n2nc(C(=O)Nc3nc4c(s3)CCC4)nc2n1 +CC1CCC(NC(=O)c2ccccc2-n2cnnn2)CC1 +O=C(NCC(O)c1ccc(Cl)cc1)c1ccc(-c2cc[nH]n2)cc1 +CN(C)c1ccc(C(=O)N2CCCCCC2c2ccncc2)cn1 +CCCCn1nnc(NC(=O)c2ccccc2OC)n1 +COc1cc(N)ccc1NC(=O)c1ccc(F)c(F)c1 +CCOC(=O)N(C)c1ccc(NCC(C)C)cc1 +O=C(NC1CC1)c1cc(C(F)(F)F)nc(C(F)(F)F)c1 +Cc1nc(-c2cc(C(=O)Nc3ccccc3C(N)=O)n(C)c2)cs1 +O=C(NCc1nnc2ccccn12)c1ccc(Cl)cc1Cl +O=C(NCC(=O)N1CCCc2ccccc21)c1cccc(Cl)c1 +O=C(Nc1cccnc1)c1ccc(NC(=O)c2ccccc2F)cc1 +Nn1c(SC2CCCC2)nnc1C(F)(F)F +O=C(c1cn[nH]c1)N(Cc1ccc(Cl)cc1)C1CC1 +CN1CC(C(=O)NCc2ccc3c(c2)OCO3)CC1=O +Cc1ccc(C(O)CNS(=O)(=O)Cc2ccc(F)cc2)o1 +Cc1ccc(OCC(=O)NCCNC(=O)c2ccccc2O)cc1 +N#CCCN(Cc1cccnc1)C(=O)c1cc(Cl)c2c(c1)OCO2 +CCCCCNC(=O)CS(=O)(=O)c1ccc(F)cc1 +CCCc1cc(NC(=O)c2ccc3[nH]cnc3c2)n[nH]1 +Cc1nc2ccccc2n1C1CC(C)CCC1C#N +NC(=O)C1CN(Cc2ccc(F)cc2OC(F)(F)F)CCO1 +CC(NCc1ccc(S(C)=O)cc1)C(=O)NCc1ccco1 +COCC1CCCN(C(=O)CCSc2ccccc2)C1 +Cc1ccc(OCC(=O)N(CCO)CCO)cc1C +COCC(C)N1CC(C(=O)Nc2cc(Cl)ccc2OC)CC1=O +COC(=O)C(CO)NC(=O)c1cc(C)ccc1F +CCOc1cccc2cc(S(=O)(=O)c3ccccc3F)c(=O)oc12 +Cn1cc(C2NCCc3c2ccc(F)c3Cl)cn1 +CCOC(=O)C1=C(C)C(NC(=O)OCc2ccccc2)=NC1C +O=C(NCCS(=O)(=O)c1ccccc1)N1CCc2ccccc21 +CC1CN(C(=O)CNC(=O)Cc2ccccc2)C(C)CO1 +CC(C)CCC(=O)N1CCN(CC(=O)NC(C)C(=O)N(C)C)CC1 +Nc1nc(CCOc2ccccc2)ncc1C(=O)NC1CC1 +Oc1ccc2c(c1C(F)(F)F)C(c1cnccn1)NCC2 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccco2)CC1 +Cc1nnnn1-c1cccc(NC(=O)NCCc2nc(N)no2)c1 +O=C(C1CC1)N1CCN(Cc2cc(-c3ccco3)on2)CC1 +CCC(CC)c1nc2cc3c(cc2n1CCC#N)OCCO3 +O=C(NCc1nc(C2CC2)no1)Nc1cccc2c1OCCO2 +COCc1ccc(C(=O)N2CCN(Cc3csc(C)n3)CC2)o1 +COc1ncccc1CNC(=O)N1CC(C)OC(c2ccccc2)C1 +CC(C)CCn1c(=O)c2sccc2n2c(=O)n(C)nc12 +Cc1nccc(CNC(=O)c2ccc3[nH]cnc3c2)n1 +CCc1ccsc1C(=O)N1CCCC(NS(C)(=O)=O)C1 +Nc1cc(N)nc(SCc2ccc3c(c2)OCO3)n1 +Cc1csc(=O)n1CCC(=O)N(C)CCc1ccccn1 +COc1cc(C)c(NC(=O)c2cccc(Cl)c2)cc1OC +COC(=O)c1ccccc1NCCC(=O)c1cccc(N)c1 +Cc1c(C(C)NC(=O)CCc2ccccn2)cnn1C +Cc1nn2cc(C(=O)NCc3ccc(C(C)(C)C)cc3)nc2s1 +Cc1csc(CNC(=O)NC(C)COCC(F)(F)F)n1 +Cn1nc2n(c1=O)CCN(CC(=O)c1c[nH]c3ccccc13)C2 +O=C(Cc1ccsc1)N1CCCC(CCO)C1 +O=C(NCc1ccc(Cl)cc1)c1cc(Cl)ccc1-n1cnnn1 +Cn1cc(NC(=O)CNC(=O)C(C)(C)C)cc(Br)c1=O +O=C(NCCc1ccc(F)cc1)NCc1cc(=O)[nH]c2ccccc12 +CCOC(=O)CN(C(=O)c1ccccc1Cl)C1CC1 +COc1ccccc1OCCCN(C)C(=O)C1CC12CC2 +CCCS(=O)(=O)NCc1ccc(Cn2ccnc2)cc1 +COc1ccc(CN2CCN(C(=O)c3ccc(C)nc3)CC2)cn1 +C#CCN1CCC(NC(=O)Nc2ccc(F)cc2)C1 +COCCN(CC(C)C)C(=O)c1cc(-c2csc(C)n2)c[nH]1 +Cc1onc(-c2ccccc2)c1C(=O)N(CC(C)C)CC(C)C +Cc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1 +CNC(=O)c1ccc(NS(=O)(=O)c2c(F)cccc2F)cc1 +N#Cc1ccc(NC(=O)Cn2nc3ccccn3c2=O)cc1 +COc1ccc(Oc2cc(CNC(=O)C3CCCO3)ccn2)cc1 +Cn1cnnc1SCC(=O)NCc1ccccc1 +CN(C)S(=O)(=O)N1CCN(C(=O)c2ccc3c(c2)CCO3)CC1 +FC(F)(F)Oc1ccc(CCNCc2ccccn2)cc1 +CC(C)(C(=O)NCc1ccncc1)c1ccc(N)cc1 +Cc1csc(C(C#N)C(=O)c2cccc(OCc3cccnc3)c2)n1 +Cc1cc(C)n(CC2CCCCN2Cc2nnnn2C2CC2)n1 +Cc1cccc(OCCNC(=O)Cc2ccc(F)cc2)c1 +O=C(CCNC(=O)NC1CCc2cc(F)ccc21)NC1CCCCC1 +Cc1cc(C)n(C2CCCN(C(=O)c3ccc4[nH]c(=O)[nH]c4c3)C2)n1 +CC(C)(C)c1csc(CN2CCNC(=O)C2)n1 +Cn1c(C(=O)N2CCCCCC2)cc2sccc21 +COC(=O)c1ccc(C(=O)NCC(=O)Nc2cn[nH]c2)cc1 +O=C(c1ccncc1F)N(CCc1ccccc1)Cc1ccccc1 +Cc1cc(C)n(-c2nc3c(c(=O)n(C)c(=O)n3C)n2CCC(C)C)n1 +Cc1nn(C)c(C)c1NC(=O)c1cc(C(C)C)nc(N(C)C)n1 +COCCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1OC +O=S(=O)(Cc1ccccc1Cl)c1ccccn1 +CC(C)OCCC(=O)Nc1ccccc1Br +CCN(Cc1ccccc1)C(=O)c1scnc1C +Cn1cc(C(N)=O)cc1C(=O)OC1C2CCCOC2C1(C)C +CCc1onc(C)c1NC(=O)CCCNC(=O)C(C)(C)C +CC(=O)c1sc(NC(=O)c2ccc(SC(C)C)cc2)nc1C +CC(C)C(=O)c1ccccc1NC(=O)C1CC(=O)N(C2CCCC2)C1 +CN(C)c1cc(NS(C)(=O)=O)ccc1OC1CC1 +CC(NS(=O)(=O)c1ccccc1)C(=O)N1CCC1 +N#Cc1cc(NC(=O)N2CCCN(CC(F)(F)F)CC2)ccc1F +COc1ccc(C(=O)Nc2cc(S(N)(=O)=O)cc(C)c2C)cc1 +CN(C)c1ncccc1C(=O)NCc1ccnc(OC2CCC2)c1 +CC(=O)N1CCCN(C(=O)c2cnc3ccc(C)cn23)c2ccccc21 +CC(=O)Nc1ccc(OS(=O)(=O)c2ccc3ccccc3c2)cc1 +CCc1nc2n(n1)CCCC2NS(=O)(=O)c1ccccc1F +CNC(=O)c1cccc(CCNC(=O)c2c(C)cc(C)cc2C)c1 +NC(=O)N1CCCC(C(=O)OC2CCCCC2)C1 +CCSc1ccc(NC(=O)c2sc(C)nc2C)cn1 +N#Cc1ccc(F)c(CNc2ccc(F)cc2F)c1 +O=C(C(NCc1cccc2c1OCO2)c1ccccc1)N1CCCC1 +O=C(c1cccc2c1OCO2)N(CCO)Cc1ccccc1 +O=C(c1cccc2ccccc12)N1CCC(Oc2ccccn2)CC1 +COc1ncccc1CNc1nc(-c2ccncc2)nc2ccccc12 +Cc1ccccc1CC1C(=O)N(C)c2ccccc21 +O=C(Nc1cccc(N2CCCNC2=O)c1)C1CC1(Cl)Cl +Cc1ccc(N2CCC(C(=O)NCC(=O)N(C)C)C2=O)cc1C +CC(=O)Nc1cccc(-c2ccc(O)c(Cl)c2)c1 +CC(=O)Nc1ccc(NS(=O)(=O)c2ccc3c(c2)CCCC3)cc1 +O=C(Cn1nnc2ccccc2c1=O)Nc1cccnc1-n1cccn1 +CC(NC(=O)CCn1c(=O)n(C)c2ccccc21)C1CCCO1 +O=C(NCc1ccc(F)cc1C(F)(F)F)c1csnn1 +Fc1ccc(-n2ncc3c2ncn2nc(-c4cccnc4)nc32)cc1 +O=C(Nc1ccccc1F)c1c[nH]c2c(Cl)cccc2c1=O +C=CCN(Cc1cccc(F)c1)S(=O)(=O)c1cccs1 +Cc1oc(-c2ccccc2)nc1Cn1nc(C)c2c(C)onc2c1=O +OCc1cn(Cc2ccc(Br)cc2)nn1 +Cc1noc(C(C)Nc2cccc(NS(C)(=O)=O)c2)n1 +O=C(CN1CCCC1=O)Nc1ccccc1SC(F)F +Cc1cccc(C(=O)Nc2cccc(N3CCCS3(=O)=O)c2)c1C +CCOc1ccccc1C(=O)Nc1ccc(CN2CCCC2=O)cc1 +COc1ccc2c(ccn2CC(=O)NCC(C)c2cccs2)c1 +O=C(OCc1ccccc1)C1CCCN1C(=O)CCc1ccco1 +CC1CCCC(OC(=O)c2ccc3c(c2)OCC(=O)N3)C1 +CCN(C(=O)c1ccc(OCC(=O)NC)c(OC)c1)C1CCCC1 +CC(C)CNC(=O)c1cc(S(=O)(=O)N(C)C(C)C)ccc1F +O=C(c1ccc2cc[nH]c2c1)N1CCC(C(O)Cc2ccccc2)CC1 +Cc1occc1C(=O)N1CCC(NC(=O)Cn2ccccc2=O)CC1 +CC(CC#N)N(C)C(=O)Cc1ccc(C(F)(F)F)cc1 +CCOc1cccc2cc(C(=O)NCCCOC)c(=O)oc12 +Cc1cc(C)cc(OCCNC(=O)Nc2cnn(C)c2)c1 +Cc1cc(C(=O)Nc2cc(C)nn2Cc2ccccc2)n(C)n1 +Cc1ccc(CN(C)C(=O)c2ccnc(OC3CCC3)c2)cc1 +CN(C)C(=O)CN(C)C(=O)CCc1ncc(-c2ccc(Cl)cc2)o1 +NC(=O)c1ccccc1-c1ncc(-c2ccccc2)o1 +Cc1cccn2c(C#N)c(-c3ccc4c(c3)OCCO4)nc12 +CCC(CC)NC(=O)c1cccnc1SCc1cc(C)on1 +O=C(CCc1cc(=O)[nH]o1)N1CCN(Cc2cccc(F)c2)CC1 +CC(=O)c1ccc(NCC2CCN(c3cnn(C)c(=O)c3)CC2)nc1 +O=C(NCCc1cccc(O)c1)c1cccnc1OCC(F)F +Cc1ccc2nc(NCCCNC(=O)c3cnccn3)c(C#N)cc2c1 +CCCC(=O)NCc1nc(Cc2ccccc2)no1 +CCN1CCN(C(=O)CN(c2cccc(C)c2)S(C)(=O)=O)CC1 +CCc1ncc(C(=O)N2CCN(C(=O)Cc3ccccn3)CC2)s1 +CCc1ccc2nc(NC(=O)CNC(=O)OC)sc2c1 +O=C(NCC1CCCO1)C1CCN(C(=O)c2ccsc2)CC1 +CCOC(=O)c1ccc(-n2nc(C(C)=O)c(C(C)=O)c2C)cc1 +Cc1nc(-c2ccc(NC(=O)N3CCCCC3)cc2)no1 +CC(C)(C)NC(=O)COc1ccc(CNc2ncn[nH]2)cc1 +Cn1c(=O)c2c(nc(OCC(C)(C)C)n2C)n(C)c1=O +CN(C)C(=O)C1CCN(S(=O)(=O)c2cccs2)CC1 +C=CCCCN(C)C(=O)NCCc1cccc(O)c1 +C#CCNS(=O)(=O)c1ccc(C(=O)N(C)C2CC2)cc1 +CCN1CCc2ncnc(Oc3ccc(Cl)c4cccnc34)c2C1 +Cc1ccc(Br)cc1NC(=O)c1cnc2[nH]nc(C)c2c1 +COc1ccc(N(CCc2ccccc2)C(=O)CC#N)cc1 +Cn1nccc1C(=O)N1CC2COCC2(CN2CCOCC2)C1 +N#Cc1ccccc1S(=O)(=O)N1CCCCCC1 +C=CCNc1ncnc(N2CCC(Cc3ccccc3)CC2)c1N +O=C(CCn1nc(-c2cccs2)oc1=O)Oc1ccccc1 +Cc1cc(C)nc(-n2[nH]c(-c3ccc(F)cc3)cc2=O)n1 +CN(Cc1ccc(OCC(N)=O)cc1)S(C)(=O)=O +COc1ccc(-c2csc3ncnc(N(C)CCO)c23)cc1OC +COc1ccc(C(=O)N2CCCCC2)cc1S(=O)(=O)NC(C)C +Cc1ccc(S(=O)(=O)NCC(c2cccs2)N(C)C)cc1 +Cc1[nH]c(C(=O)N2CCN(C)CC2)c(C)c1C(=O)OC(C)C +CSc1ccccc1NS(=O)(=O)c1cn[nH]c1 +Cc1ccsc1C(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +O=C(c1ccccc1O)N1CCN(Cc2c(F)cccc2F)CC1 +CCN(CC)C(=O)c1c(C)nc(N)nc1COc1ccc(C)c(C)c1 +CCn1nc(-c2ccc(Br)cc2)ccc1=O +O=C1CCc2cc(OCCCC(=O)Oc3ccccc3)ccc2N1 +Cc1cc(C)n2nc(CC(=O)N=c3[nH]nc(-c4ccccn4)[nH]3)nc2n1 +COc1ccc(C(NC(C)=O)c2ccccc2Cl)cc1 +CC(=O)NC(C(=O)NCC(C)(C)N1CC(C)OC(C)C1)C(C)C +CC(NC(=O)C1(c2ccccc2F)CC1)c1ccc(-n2ccnc2)cc1 +Cn1c(=O)n(CC(=O)Oc2ccc3c(c2)OCO3)c2ccccc21 +CCN(C(=O)c1ccc(-c2ccccc2)[nH]c1=O)C1CCCC1 +Cc1cccc(OCCNC(=O)Cn2cnc3cc(F)c(F)cc32)c1 +CCOC1CC1C(=O)NCCNC(=O)c1ccc(Cl)c(Cl)c1 +Cc1nn(C)c2c(NCc3ccccn3)ncnc12 +CSc1ccccc1NS(=O)(=O)c1cccc(F)c1 +CCOc1ccc(SCC(=O)Nc2ccc(C(=O)NC)cc2)cc1 +CCS(=O)(=O)NCc1ccnc(OCC2CC2)c1 +Cc1ccc(SC(C)C(=O)Nc2ccc(C(N)=O)cc2)c(C)c1 +COc1cc(OC)cc(C(=O)NCC(=O)N=c2sccn2C)c1 +O=C(Nc1ccncc1)c1cccc(CNC(=O)c2ccccc2F)c1 +Cc1nc(COc2cc3oc(=O)cc(C)c3cc2Cl)no1 +Cc1ccc2c(CC(=O)NC(C)(C)CO)coc2c1 +COc1ccc(NC(=O)CSc2nncs2)cc1 +CCOC(=O)N1CCN(C(=O)Cn2ncccc2=O)CC1 +Cc1noc(C)c1Cn1ccc(-c2cccc(-c3nccs3)c2)n1 +CS(=O)(=O)NCC(=O)N1CCOC(c2ccccc2)C1 +Cc1csc(C2CCCCN2C(=O)CCc2cnn(C)c2)n1 +O=C(NCc1ncc[nH]1)Nc1cc(F)ccc1OC(F)F +Cc1cc(Br)c(NC(=O)N2CCNC(=O)C2)cc1Cl +C=Cc1nnc(C(N)c2ccc(F)c(F)c2F)o1 +Cn1nc(C2CCCN(c3cnccn3)C2)c2nccnc21 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)c1C +CCCN(Cc1cccc(Cl)c1)C(=O)C(CC)OC +CCCn1c(=O)[nH]c2cc(-c3noc(CNC(C)=O)n3)ccc21 +O=C(Nc1ccccc1)c1cccc2c(=O)c3c([nH]c12)CCC3 +COCCN1C(=O)CC(C#N)C1c1cnn(C)c1C +Cc1ccc(-n2cc(C)cn2)c(NC(=O)NCc2ncc[nH]2)c1 +CCN1CCN(C(=O)CC2Sc3ncccc3N(C)C2=O)CC1 +COCCC(=O)N1CCC(Cc2nccs2)CC1 +O=C(CC1CSc2nc3c(c(=O)n21)CCC3)Nc1cccnc1 +CC(=O)c1ccc(OCC(O)Cn2ccnc2)cc1 +Cc1ccc(-n2nnc(-c3ccc(N(C)C)cc3)c2N)cc1 +COc1cc(NC(C)=O)c(Cl)cc1C(=O)Nc1ccc(F)cc1 +Cc1ccc(CNC(=O)c2cn(C)nc2C(C)(C)C)cc1 +Cc1cc(=O)c(OCC(=O)N=c2[nH]c(C)cs2)c[nH]1 +CCOCC1CCCN(C(=O)c2cnc3ccccn3c2=O)C1 +CCC1CCCN(C(=O)CC2C(=O)N=C(c3cccnc3)N=C2C)C1 +COc1cc(C(C)=O)ccc1OCC(=O)NC1CCCCC1C +CC(=O)NCCCCCC(=O)N1CCCCCC1 +CC(=O)c1ccccc1NC(=O)COC(=O)c1ccccc1F +NC(=O)c1ccc(NC(=O)NC2(c3cccc(Cl)c3)CC2)cc1F +CC(Sc1nnc(CC(C)c2ccccc2)o1)C(=O)N(C)C +NS(=O)(=O)NCCNC(=O)c1ccc(F)cc1 +CN(c1ccccc1)S(=O)(=O)c1cccc(N)c1 +CCCSc1ccc(NC(=O)N2CCCC(C(N)=O)C2)cc1 +COCCNC(=O)c1c(N)n(C)c2ccccc2c1=O +CC(C)(C)Cc1cc(NC(=O)c2cc3ccccc3c(=O)[nH]2)[nH]n1 +Cc1cccc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 +O=C1NCCCc2[nH]c(CCCC3CCCO3)nc21 +N#Cc1cccnc1N1CCC(C(=O)c2cc(F)ccc2F)CC1 +CC(=O)N1CCC(NC(=O)c2cc(=O)c3ccccc3o2)CC1 +COCC(Nc1ncnc2ccc(F)cc12)c1ccc(C)o1 +Cc1nn2ccccc2c1C(=O)NCc1ccc(COCC2CC2)cc1 +CCC(C)C(NC(=O)CCN1CCOC1=O)c1nc2ccccc2[nH]1 +COCC(=O)N(Cc1nnc(-c2ccccc2Cl)o1)C(C)C +Cc1ccc(CNC(=O)Nc2ccc3c(c2)NC(=O)CS3)cc1 +CN(Cc1ccc(C#N)cc1)C(=O)NCc1cn(-c2ccccc2)nn1 +Cc1noc(COC(=O)Cc2c(F)cccc2F)n1 +CN1C(=O)NC2C1N(S(C)(=O)=O)CCN2S(C)(=O)=O +CCOc1cccc(CNC(=O)NCCOC)c1 +Clc1ccccc1OC1CCN(c2ncnc3[nH]ccc23)CC1 +CC1CC1C(=O)N1CCC(C(=O)c2ccc3c(c2)NC(=O)CO3)CC1 +COc1ccc2cc(CNc3ccccc3OC)c(=O)[nH]c2c1 +CC(C)CN1CCN(C(=O)c2cc3cn(C4CC4)cc3s2)CC1 +N#CCC(=O)N1CCN(CC=Cc2ccccc2)CC1 +Cc1ccc(CN(C)C(C(N)=O)c2cccc(F)c2)o1 +C=CCCCN(C)C(=O)C(C)NC(=O)c1n[nH]c2ccccc12 +COC(=O)c1ccc(CN(C)Cc2cnc3ncccn23)cc1 +O=S(=O)(Cc1cccc(F)c1)N1CCN(CC2CC2)CC1 +COc1ccc(OC)c(CC(C)(C#N)N2CCOCC2)c1 +CCNC(=O)c1ccc(-c2cccc(N)c2)cc1F +CC(C)CC(=O)N(CC(N)=O)Cc1ccc(Br)cc1 +Cc1cc(C(=O)CN2CCOCC2)c(C)n1C1CC1 +CC(NCc1ccc(F)cc1F)(C(N)=O)c1cccc(Cl)c1 +Cc1nnc2n1CCN(CC(O)c1ccc(F)cc1)C2 +Cc1noc(CCC(=O)OCCc2nc3ccccc3s2)n1 +Cc1noc(C)c1C(=O)OC(C)C(=O)NCc1ccco1 +CNC(=O)C(C)CN(C)c1ccc(C(F)(F)F)c(C#N)c1 +COc1cccc(OC)c1OCC(=O)NC1CCC(C)CC1 +COc1ccc(OC)c(CCNC(=O)Cc2c(F)cccc2F)c1 +COCc1ccc(C(=O)N2CCOCC2C2CC2)cc1 +O=c1[nH]c(COCC(F)(F)F)nc2ccsc12 +CCOc1ccccc1NC(=O)NCc1ccncc1 +O=c1cc(C(F)(F)F)nc(CNc2cccc(Cl)c2Cl)[nH]1 +Cc1nc(N)cc(N2CCN(CCn3cncn3)CC2)n1 +COc1c(CNc2nnc(C3CCCCC3)o2)c(C)nn1C +Cc1noc(C)c1C(C)NC(=O)C1CCCN(S(C)(=O)=O)C1 +COc1ccccc1OCC(=O)Nc1c(C)n[nH]c1C +Cc1cnc(NC(=O)CNC(=O)c2cccc(Cl)c2)s1 +CC(=O)c1cccc(NC(=O)c2csc(C)c2)c1 +COc1nc2ccccc2nc1CCC(=O)NCC1CCCO1 +C=CCn1c(C)nnc1SCC(O)c1cccc(F)c1 +Cc1ccc(F)cc1NS(=O)(=O)c1cccc2cccnc12 +Cc1cc(-c2nn(CCO)c(N)c2-c2nc3ccccc3[nH]2)nn1C +Cc1cccc(C(=O)OCC(=O)Nc2ccccc2)c1C +C=C1C2(C(=O)NCc3ccccn3)CCC(C2)C1(C)C +Cc1nccn1-c1cncc(C2CCCN2Cc2ccccc2)n1 +Cc1[nH]ncc1CCCNC(=O)NCC1CCN(c2ccccc2)C1 +COc1ccc(CC(NS(C)(=O)=O)c2ccccc2)cc1OC +CNC(=O)C1CCC(NC(=O)Nc2cnc(C(C)(C)C)nc2)CC1 +COC(=O)c1ccc(NC(=O)Nc2ccccc2)s1 +CC1CCN(C(=O)C2CCCN(c3ncc(C#N)cc3Cl)C2)CC1 +CCCCNC(=O)c1cc(-c2ccc(OC)cc2)on1 +COc1ccc(C)cc1-n1ccc2c(nnc3nc(C)nn32)c1=O +O=C(NCCC(=O)N1CCCC1)Nc1ccc(Cl)c(Cl)c1 +CC1(C)CC(=O)N=C(Nc2cccc(Br)c2)C(=O)C1 +O=C(CCCC(O)c1ccc(F)cc1)NCc1ccncc1 +O=C(CS(=O)(=O)c1ccc(F)c(F)c1)Nc1ccc(F)c(F)c1 +COCC(C)CN(C)C(=O)C1CC12CCc1ccccc12 +Cn1cc(S(=O)(=O)N(CC(N)=O)C2CCCC2)c(=O)n(C)c1=O +COc1ccccc1-n1c(SC)nc2ccccc2c1=O +C=CCC1(OC)CCN(C(=O)Nc2cc(C)nn2C(C)C)CC1 +NC(=O)c1ccsc1NC(=O)Cc1ccc(-c2ccccc2)cc1 +CCn1ncc(NC(=O)Cn2ncc(Br)c2C)c1C +Cc1ccc(C(=O)c2ccccc2C(N)=O)cc1C +Cc1ccsc1CNC(=O)c1c(C)[nH]c2ccccc12 +C=CCN(Cc1cccs1)C(=O)Cc1ccc(OC)cc1 +COc1ccc2[nH]cc(Cc3nc(C(C)(C)OC)no3)c2c1 +COc1cccc(Cc2nnc(NC(=O)c3scnc3C)s2)c1 +O=c1[nH]c2ccccc2c(=O)n1Cc1ccc(-c2ccccc2)o1 +CC(C)C(NC(=O)Cc1ccc(F)cc1F)c1nnc2ccccn12 +N#Cc1cccc(Cn2ccnc2CCOc2ccccc2)c1 +Cc1nccn1-c1ncccc1NC(=O)Cn1nnc2ccccc21 +CCOc1ccc(NC(=O)c2cc(NC(C)=O)ccc2O)cc1 +CC1COCCN1C(=O)C1COc2ccc(Cl)cc2C1 +FC(F)(F)c1nnc2n1CCN(c1nc(C3CC3)ns1)C2 +COC(=O)C1CCCCCC1NC(=O)Cc1ccc(OCC#N)cc1 +COc1ccc(-c2ccc(=O)n(Cc3ccc(C#N)cc3)n2)c(F)c1 +COC(=O)C1CCN(C(=O)c2cn3cccnc3n2)CC1 +N#CCCCOc1cccc(NCc2ccc3c(c2)CCO3)c1 +Cc1nn(C)c(C)c1C(=O)N1CCN(CCc2cccs2)CC1 +CC(Oc1ccccc1)C(=O)Nc1cccnc1-n1cccn1 +CNS(=O)(=O)c1cccc(C(=O)N(Cc2ccncc2)C2CC2)c1 +CC1CCCC(C)N1C(=O)CSc1nnc(-c2cccnc2)n1C +O=C(Nc1cccc(CNC(=O)C2(O)CCCC2)c1)C1CCCC1 +CCN1CC(C)Oc2ccc(S(N)(=O)=O)cc21 +O=C(COC1CCCCC1)NCCNC(=O)c1ccccc1O +CN(Cc1nc2c(s1)CCCC2)c1cnccn1 +Cc1cc(NC(=O)CCc2ccc3c(c2)OCO3)no1 +Cc1ccc(NC(=O)Cc2cn3ccccc3n2)c(C)c1 +CC(C)NC(=O)CC1COC2(CCN(c3nncs3)CC2)C1 +COc1ccc(C)cc1-n1nnc(CO)c1C(C)C +CC(C)Oc1cc(-c2ccccc2)cn(CCO)c1=O +CC(NC(=O)c1cn(Cc2ccc(F)cc2)nn1)c1cnn(C)c1 +COc1ccccc1CNC(=O)C(C)Sc1ncnc2nc[nH]c12 +CCCN(CCC)C(=O)C(C#N)Cc1ccc(C#N)cc1 +Cc1coc(-c2nc3c(s2)CC(CO)CC3)n1 +CCC(C)NC(=O)CS(=O)(=O)c1ccccc1 +Cc1ccc(S(=O)(=O)N2CC(OCc3cccc(F)c3)C2)cc1 +CCCc1nc2cc3c(cc2n1CC(C)C#N)OCO3 +Cc1nc(C2CCCN(C(=O)c3cc4cc(Cl)ccc4o3)C2)no1 +Fc1ccc(OCCCn2cc(Br)cn2)cc1 +O=C(c1nccc2ccccc12)N1CCN(Cc2ccncc2)CC1 +Cc1ccc2c(c1)CCCN2C(=O)c1ccc(N(C)C)nc1 +COc1ccc(CN(C)C(=O)CS(=O)(=O)c2ccccc2C)cc1 +COc1cc(NC(=O)CNc2cc(C)cc(C)c2)cc(OC)c1OC +CC(CC#N)N(C)Cc1c[nH]nc1-c1ccccc1 +CCN(CC)C(=O)N1CCC(C(=O)N(C)Cc2cc(C)on2)CC1 +CCOC(C)C(=O)Nc1sc(C(C)(C)C)cc1C(=O)OC +Cc1nc(CC(C)C)sc1C(=O)Nc1ccc(C(N)=O)cc1 +CCOC(=O)N1CCCC(C(=O)Nc2ccc(OC)c(OC)c2)C1 +CCOCC1CCCN(C(=O)NCc2ccc(C(=O)N(C)C)cc2)C1 +CN(Cc1cccc(Cl)c1)C(=O)NCc1nnc2n1CCC2 +CCc1nnc(C(=O)Nc2ccc(C(=O)NC(C)CC)cc2)s1 +CC(=O)Nc1cccc(NC(=O)c2cccc(C)c2C)c1C +N#CC1(NC(=O)c2ccc(N3CCNC3=O)cc2)CCCCC1 +O=S(=O)(Nc1ncccn1)c1ccc(OC(F)(F)F)cc1 +COc1ccccc1C1(CNC(=O)NCc2nc(C)c(C)s2)CC1 +Cc1cc(=O)oc2cc(OCC(=O)NCCCO)c(Cl)cc12 +CC(=O)Oc1ccc(C(=O)c2cccc(F)c2)cc1 +O=C(c1cscn1)N1CCC(c2n[nH]c3ncccc23)CC1 +O=C(NCc1ccncc1)c1cc(-c2ccccc2Cl)[nH]n1 +CN(C)c1nc(CNc2ccc(-n3nccn3)cc2)ns1 +Cc1nc2ncnc(N3CCc4ccccc43)c2[nH]1 +Cn1nnnc1SCC(=O)NCCn1ncccc1=O +CCCNC(=O)C1CCN(c2ccc(Cl)cn2)CC1 +CCn1cc(C(=O)Nc2ccc(F)c(C#N)c2)cn1 +O=C(CC1CCOC1)N(c1ccccc1F)C1CCCC1 +Cc1ccc(F)c(C(=O)NCC(=O)NC(C)C)c1 +COC(=O)c1[nH]cc(-c2ccc(Cl)cc2)c1N +COc1cccc(-c2cc(C(=O)NCC(O)CO)[nH]n2)c1 +N#Cc1ccccc1Oc1ccc(NC(=O)N2CCCC2CO)cc1 +COC(=O)c1c(C)nn2c1ncc1c(=O)n(C3CC3)ccc12 +Cc1cc(NC(=O)c2cc3ccccc3o2)sn1 +COCCNC(=O)NC(C)c1ccc(Cl)c(Cl)c1 +COc1ccccc1NC(=O)CCN1CCOC1=O +Cc1nn2c(=O)cc(CN(C)Cc3c(C)noc3C)nc2s1 +COc1cc(C)c(-c2nc(C)c(CO)s2)cc1C +Cc1nc(C)c(C(=O)NC2CC(C)(C)OC2(C)C)s1 +CCc1nnc(NC(=O)CCCOc2ccc(C)cc2C)s1 +COc1cc(C#N)ccc1OCc1nc(C(C)(C)OC)no1 +Cc1nc(C)n(CC2CN(CC3(O)CCCCC3)CCO2)n1 +CCOc1c(Cl)cc(C(=O)NCC2CCCO2)cc1OC +COc1cc(CN(C)C(=O)NC(C)C(=O)N(C)C)ccc1SC +C=CCn1c(=O)nc2n1C(=O)N(c1ccc(Br)cc1)C2 +CCc1nn(C(C)c2ccccc2)c2c1C(=O)CCC2 +CCCCNC(=O)N1CCN(CC(=O)N2CCCCC2)CC1 +COc1ccc(C(O)CCNc2ccc(C(C)=O)cc2)cc1 +CC(=O)NC(C(=O)Nc1nc(C(C)=O)cs1)C(C)C +Cc1ccccc1N1CCCN(C(=O)C2CCOCC2)CC1 +COc1ccc(NC(=O)C2CCCCC2)cc1-n1cnnn1 +COc1cccc(Cn2nc(-c3cccc4ncccc34)oc2=O)c1 +Cc1cc(C)c2c(c1)CCNC2CSc1ncccn1 +CCC1CCCN(C(=O)c2cnn(-c3ccccc3C)c2C)C1 +CNC(=O)Cc1ccc(NC(=O)NC2CCCC2)cc1 +C#CCN1C(=O)C(c2ccccc2)Oc2c(OC)cc(CO)cc21 +CC(Cc1ccco1)NS(=O)(=O)c1csc(C(N)=O)c1 +O=C(CC1(O)CCCCC1)Nc1cnn(CC(=O)N2CCCC2)c1 +O=C(Nc1nc(SCc2ccccc2)ns1)C1CCC1 +CCc1n[nH]c(C2CN(CCOc3ccc(C#N)cc3)CCO2)n1 +CSc1ccsc1C(=O)NCC1CN2CCCCC2CO1 +COC(=O)c1cnn(-c2cccc(NC(C)=O)c2)c1N +CC(NC(=O)N(Cc1ccccc1)CC1CCC1)C(=O)N(C)C +Cc1nc2ccccc2n(C(C)C(=O)Nc2ccccc2Cl)c1=O +C=CCn1c(COC)nnc1SCc1ccccc1C +CCCn1cc(NC(=O)NCc2cc(=O)[nH]c3ccccc23)cn1 +Cc1cccc(C(=O)NC(C)C(=O)N(C)CC2CC2)c1 +Fc1ccc(-c2nnc3sc(C=Cc4cccnc4)nn23)cc1F +Cn1cc(CC(=O)NC(C(N)=O)C(C)(C)C)c2ccccc21 +COc1ccc(CCC(=O)N2CCc3ccccc32)cc1OC +COC(=O)c1c(NC(=O)CC(C)C)c(C)nn1C +CN(C)c1cc(C(=O)N2CCN(c3cc(C#N)ccn3)CC2)ccn1 +COCCn1cnnc1SCc1csc2ccccc12 +Cc1cn2c(CN(C)C(=O)c3cc[nH]c3C)c(C)nc2s1 +CS(=O)(=O)Nc1ccc(S(=O)(=O)NC2CC2)cc1 +CCOC(=O)Nc1ccc(NS(=O)(=O)c2ccccc2)cc1 +Cc1cccc(Nc2nccc(-c3cn(C)nc3C)n2)c1C +CCn1nc(CC(C)C)cc1C(=O)NCc1cc(C)nc(C)c1 +CCOc1ccccc1OCc1nc(C)c(C(C)(C)O)s1 +CCNC(=O)c1c(C)nc(N)nc1-c1ccccc1OC +O=C(NCC(O)c1ccc2c(c1)CCO2)c1ccccc1F +Cc1ccccc1-c1nnc(SCC(N)=O)n1Cc1ccccc1 +COc1ccccc1C1NC(=O)c2ccccc2N1C +COc1ccc2nc(C)cc(-c3nc(C(C)(C)OC)no3)c2c1 +COCCCn1ccc(NC2CCN(c3ccccc3Cl)C2=O)n1 +O=C(Cn1ncc2ccccc2c1=O)Nc1ccc2c(c1)COC2 +O=C(C1CCC1)N1CCCN(C(=O)C2CCC2)c2ccccc21 +Cc1noc(C2CCCN(Cc3ccncc3)C2)n1 +CCC(C)(C)NC(=O)CNC(=O)Cc1ccccc1 +CNS(=O)(=O)c1ccc(C(=O)N(C)Cc2ccc(OC)cc2)o1 +O=C(Nc1nccs1)c1ccc(Br)cc1F +FC(F)(F)c1ccc2oc(CN3CCOCC3C3CC3)nc2c1 +Cc1cc(-n2ncc3c(=O)[nH]cnc32)ccc1Br +Cc1nn(C)c(C)c1CC(=O)Nc1ccc2c(c1)OCC(=O)N2 +CNC(=O)c1ccc(S(=O)(=O)NCc2ccoc2)cc1 +CN1CC(C(=O)NCC(=O)c2cccc3ccccc23)CC1=O +O=C(NC1CCCCc2ccccc21)N1CCC(c2nc[nH]n2)CC1 +Cc1occc1COC(=O)C1CCCN(C(=O)C2CC2)C1 +COc1cc(CNC(=O)c2sc(-c3cccs3)nc2C)ccn1 +Cc1c(C(=O)OCC(=O)N2CCCC2)oc2ccc(Cl)cc12 +Cc1c(C(=O)NCCc2ccco2)[nH]c2c1C(=O)CCC2 +O=C(COc1ccccc1)NCC(O)c1cccc(C(F)(F)F)c1 +c1ccc(OCCOCCn2nnc3ccccc32)cc1 +COc1ccc2occ(C(=O)c3ccc(N)cc3)c2c1 +COc1ccccc1CNC(=O)Nc1ccc(C)c(C(N)=O)c1 +CCN(CC)C(=O)c1ccc(Br)cn1 +Oc1ccc2c(c1)C(c1ccc3ccccc3n1)NCC2 +CC(C)Cc1cc(C(=O)N(CCO)Cc2ccccc2Cl)on1 +CC(O)(CNC(=O)c1cccnc1OCC(F)F)c1ccsc1 +COc1cc(F)c(C(O)C2CCCCO2)c(F)c1 +CN(c1ccccc1)S(=O)(=O)c1ccc(C(N)=O)cc1 +CC(=O)c1c(C)nc(C)nc1SCc1nc(-c2ccco2)no1 +C=CCOC(C)C(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +O=C(Cc1cccs1)Nc1ccccc1C(=O)NC1CCCC1 +O=C(NCc1ccccc1F)C1CN(S(=O)(=O)C2CC2)C1 +CCCn1c(=O)c2ccccc2n2c(SC(C)C#N)nnc12 +O=C(CNC(=O)NC1CCN(c2cccc(F)c2)CC1)NCC1CC1 +CCCNC(=O)C1CCCN(C(=O)NCC2CC=CCC2)C1 +O=C(CO)N1CCN(C(=O)c2cncn2-c2ccccc2)CC1 +CS(=O)(=O)NCCOC(=O)c1cc(Cl)ccc1F +COc1ccc(-c2ncc(C(=O)N3CCOCC3C3CC3)s2)cc1 +CC(=O)NCC(=O)N1CCC(c2sccc2C)C(O)C1 +Cc1cc(NC(=O)C(c2ccccc2)N2CCCCC2=O)sn1 +CNS(=O)(=O)CC(=O)N(C)c1ccc(-c2ccccc2)cc1 +COc1cncnc1NS(=O)(=O)c1ccc(N)cc1 +CC(C)c1ccc(C(O)CNC(=O)c2ccc3c(c2)OCO3)cc1 +Cn1cnc(CNC(=O)C2(Cc3ccccc3)CCC2)n1 +NC(=O)CSc1nnc(NC(=O)Nc2ccc(F)cc2)s1 +O=C(NCc1cccnc1)c1cc2cnc3[nH]ccc3c2s1 +Cc1ccc(NC(=O)COC(=O)c2cc(=O)[nH]c3ccccc23)cc1 +Cn1cc(C(=O)Nc2cc(=O)n(C)c(=O)n2C)cn1 +c1ccc(-c2nc(-c3ccc4c(c3)CCN4)cs2)nc1 +CCOC(=O)c1c2n(c3ccc(F)cc3c1=O)CCS2 +O=C(C1CCC1)N(c1ccc(O)cc1)S(=O)(=O)c1ccccc1 +CCN1CC(CN(C)C(=O)c2ccc(C)c(F)c2)Oc2ccccc21 +CC(=O)c1c(-c2ccc(Br)cc2)cnn(C)c1=O +COc1ccc(-c2c[nH]c(N)c2C#N)cc1Br +CNC(=O)NCC(O)COc1cccc2ccccc12 +CCCOC1CCCN(C(=O)Cn2cc(C)c(=O)[nH]c2=O)C1 +CC(C)(Oc1ccc(F)cc1)C(=O)N(CCC#N)Cc1cccnc1 +N#CC(CCC(=O)NCc1ccco1)c1cccnc1 +CCC1NC(=O)C2CN(CC3CCCCC3)CCN2C1=O +O=C(NC(c1ccccc1)C1CCC1)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +N#Cc1c(-c2ccccc2F)nn(-c2ccncc2)c1N +CCCOC(=O)CN1C(=O)COc2ccc(C(C)=O)cc21 +Cn1ccnc(Oc2cccc(Br)c2)c1=O +O=C(C1CC1)N1CCC(O)(CNc2ccccc2)CC1 +Cc1ccc(NS(=O)(=O)c2ccc(C(=O)NC3CC3)cc2)cc1 +CCOc1ccccc1C(=O)NCC(=O)Nc1nnc(CO)s1 +CC(=O)Nc1ccc(C(=O)N2CCOCC2C2CC2)cc1 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)OCc1ccon1 +CC(=O)Nc1ccc(CNc2cccc(O)c2)cc1 +Cc1cc(=O)n(CC(=O)NCCn2ccnc2)c2ccccc12 +COc1cc(C)c(C)cc1CC(OC)(OC)OC +COc1cccc(CNC(=O)Nc2ncc(C)s2)c1OC +CCOCc1ccc(C(=O)Nc2ccc(C)cc2)o1 +NC(=O)c1nnn(-c2cccc(C(F)(F)F)c2)c1-c1ccccc1 +COC(=O)c1sccc1Cn1nnn(-c2cccs2)c1=O +Cc1csc(CNC(=O)c2cc(Cl)ccc2Cl)n1 +CC(=O)N1CCc2cc(S(N)(=O)=O)c(Cl)cc21 +CC(=O)Nc1ccc(Nc2ccc(-n3nc(C)c(C)c3C)nn2)cc1 +COc1ccc(CN2CC(C(=O)N(C)C(C)C)CC2=O)cc1 +Cc1ccccc1CCNC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +O=C(Cn1nnc2ccccc2c1=O)N1CCCC1c1nccs1 +Cn1cc(NC(=O)c2cc3ccccc3s2)c(=O)n(C)c1=O +Cc1ccc(C(C)NC(=O)Nc2cnccc2C)cc1F +CCOC(=O)c1c(NC(=O)c2ccc(F)cc2)sc(C(C)=O)c1C +COC(=O)C1Cc2ncn(C)c2CN1C(=O)c1cccs1 +COc1cc(C(=O)NCC2CN(C(C)=O)CCO2)nc(OC)n1 +Cc1ccc(-n2nc(C(=O)N3CCCCC3)c(=O)n(C)c2=O)cc1 +Cc1cc(CNC(=O)c2sccc2OC(F)F)c(C)o1 +CC(C)(C)OC(=O)Nc1cc(NC(=O)c2ccnnc2)ccc1F +Cc1nnnn1-c1cccc(NCc2nnc(-c3ccccc3)n2C)c1 +CC1(C)C(NC(=O)NCCS(=O)c2ccccc2)C2CCOC21 +COc1cccc(C(N)=O)c1OCc1nsc(N(C)C)n1 +COc1ccc(CN(C)Cc2cnc(C(C)C)s2)cc1O +CC(C)C(Sc1ccccc1)C(=O)N1CCC(C(=O)N(C)C)CC1 +CCn1cc(S(C)(=O)=O)c(=O)c2cc(F)c(N3CCCC3)cc21 +Cc1ncsc1CCN(C)C(=O)C1CC(=O)N(C2CC2)C1 +CCOCCSc1nc(C)cc(C(F)(F)F)c1C#N +c1cnc(N2CCN(CCn3ccnc3-c3c[nH]cn3)CC2)nc1 +C#CCOC(=O)c1ccc2oc(-c3ccncc3)nc2c1 +O=C(NC1CCCCC1C(F)(F)F)c1cnccn1 +Cc1nc(CNC(=O)c2cncc(OC(C)C)c2)c(C)s1 +O=C(Cn1cnc2c([nH]c3ccccc32)c1=O)NCc1ccco1 +CSc1cccc(NC(=O)C(C)NC(=O)C(C)(C)C)c1 +CCCCc1nnc(NC(=O)Nc2cnn(C)c2)s1 +NC(=O)c1csc(CN2CCCC(C(=O)c3ccc(F)cc3)C2)c1 +CCN(CC1CC1)C(=O)CCc1c(C)nc(-c2cccnc2)[nH]c1=O +COc1c(Cl)cccc1NC(=O)c1sc(C)nc1C +CC(=O)c1ccc(NCC(O)c2ccc3c(c2)OCO3)cc1 +Cc1ccc(CCC(=O)Oc2ccc(S(=O)(=O)N(C)C)cc2)cc1 +COc1ccc2[nH]cc(C(=O)COc3ccccc3)c2c1 +CN(C)c1nccnc1C1CCN(c2cnccn2)CC1 +Cc1ccc2c(CC(=O)Nc3ccc(-n4cc[nH]c4=O)cc3)coc2c1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccc(C#N)cc2)cc1 +CCN1C(=O)Cc2cc(NC(=O)NCc3ccccc3)ccc21 +CC(C)C(=O)N1CCCC1C(=O)OCC1CC=CCC1 +Cc1ccc(OC(=O)c2cc3c([nH]c2=O)CCCC3=O)cc1 +CCCCN1C(=O)C(NC(C)=O)c2c(Cl)ccc(OC)c21 +Cc1nc(-c2ccncc2)[nH]c(=O)c1CC(=O)N(C)C(C)C(C)(C)C +CCC1CN(C(=O)c2[nH]c3c(c2C)C(=O)CC(C)(C)C3)CCO1 +Cc1cc(CSc2nnc(C3COc4ccccc4O3)o2)no1 +COc1ccc(Br)c(C(=O)NCC2CC2)c1 +Cc1noc(C2CN(Cc3csc(-c4ccccc4)n3)C2)n1 +Cc1cc(-c2nc3sc(C4CC4)nn3c2CO)ccc1Cl +COC(C)C(=O)Nc1cccc(S(=O)(=O)N2CCCCCC2)c1 +Cc1ccccc1C1CC1c1nc(-c2ccncc2)no1 +CC(C)n1c(NC(=O)Nc2ccccc2F)c2ccccc2nc1=O +Cc1cc(C(=O)Nc2nc3ccccc3s2)n(C(C)C)n1 +CS(=O)(=O)c1ccc(NC(=O)Cc2ccc3ccccc3c2)cc1 +CN(CCC#N)C(=O)c1cccc(-n2cnnn2)c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)N1CCc2sccc2C1C +CCC(NC(=O)Cn1cc(N)ccc1=O)C(C)C +Cn1cnnc1SCCNc1ncccc1Cl +COC1CCCN(C(=O)Nc2nn(-c3ccccc3Cl)cc2C)C1 +Cc1cccc(CN(C(=O)c2ccc(S(C)=O)cc2)C2CC2)c1 +Cc1occc1COC(=O)C1CCCCN1C(=O)c1ccco1 +CC(C)Oc1ccccc1NC(=O)c1cccc(OCC(F)F)n1 +Cc1n[nH]c(C)c1NC(=O)CCC(=O)c1ccc(F)c(F)c1 +Cc1csc2nc(CNc3cc(Cl)ccc3F)cc(=O)n12 +COCCN(Cc1ccsc1)C(=O)c1ccno1 +N#Cc1cnc2ccccc2c1NC(=O)COC1CCCC1 +CC(=O)Nc1cccc(NC(C)C(=O)N2CC(C)CC(C)C2)c1C +CC(NC(=O)CC(F)(F)F)c1nc(C(C)(C)C)cs1 +CNC(=O)NCC(=O)Nc1ccc(OCc2ccccc2)cc1C +CCC(CC)N(CCO)C(=O)c1ccc(C)c(C)c1 +Cc1cccc(OCc2nnc(SC3CCCCC3=O)o2)c1 +O=C(CCC(=O)c1ccccc1)Nc1nc(-c2ccccn2)cs1 +COCC(C)OC(=O)c1cn(C)nc1-c1ccccc1Cl +COc1cc(OC)c(NC(=O)N2CCCC(CO)C2)cc1Cl +CCC(C)NC(=O)c1ccc(CNC(=O)c2ccccn2)cc1 +COc1ccc2c(c1)nc(C1CC1)n2Cc1cccnc1N +COc1cc(CNc2ccc(C#N)cn2)ccc1C +CC(=O)Nc1ccc(S(=O)(=O)Oc2ccc(F)cc2Cl)cc1 +C#Cc1cccc(NC(=O)Cc2ccc(OC)c(OC)c2OC)c1 +O=C(CN1CCN(C(=O)CCC2CCCC2)CC1)NC1CCCCC1 +CCNC(=O)c1cn(-c2ccc(C)cc2)nc1-c1cccc(OC)c1 +Cc1cc(F)cc(C(=O)NCCNC(=O)Cc2ccc(F)cc2)c1 +Cn1cc(CCC(=O)Nc2cc(Cl)ccc2C(N)=O)cn1 +O=C(c1ccccc1)N1CCN(c2nc3c(c(=O)[nH]2)CCCC3)CC1 +Cn1ccc(NS(=O)(=O)c2ccccc2F)n1 +CCOC(=O)C(CO)NC(=O)C1(NC(C)=O)CCCC1 +Brc1ccccc1OCCCCN1CCOCC1 +CCc1onc(C)c1NC(=O)c1ccc(OCc2ccccn2)cc1 +Cc1ccccc1-c1nc2ccccc2n1CC(=O)NC1CC1 +CC(=O)NCCC1CCCN(c2nc(C)cc(C)n2)C1 +Cc1nc2ccccc2n1CCNS(=O)(=O)Cc1ccccc1 +Cc1cc(C2CCCN2C(=O)NCc2ccc(C)s2)on1 +Cc1ccc(-c2noc(CCNC(=O)c3cccs3)n2)cc1 +Cc1ccccc1CNC(=O)c1nc(C)n(-c2ccc(F)cc2)n1 +CN(C)S(=O)(=O)NC(c1ccc(F)cc1)C(C)(C)C +CC1CCCCN1C(=O)c1cc(CN2CCOCC2)on1 +CN(C)C(=O)c1cccc(OS(=O)(=O)c2cccnc2)c1 +COc1ccc(C)cc1NCC(=O)NC1(C#N)CCCC1 +CCCC(=O)NC(C)c1nc2ccccc2n1CCC +CC(C)(C(=O)NCCO)c1ccc(Br)cc1 +CN(CCC#N)C(=O)C(c1ccccc1)c1ccccc1 +CC(C)CC(NC(N)=O)C(=O)NCC(F)(F)F +Cc1cc(C)nc(N(C)C2CCCN(C(=O)OC(C)(C)C)C2)n1 +Cc1cc(C)c2oc(=O)cc(CN3CCC4(CC3)OCCO4)c2c1 +CCn1cc(CN2CCCN(c3ccc(C)nn3)CC2)cn1 +CC(C)CN(CC(N)=O)S(=O)(=O)Cc1ccc(F)cc1 +CC1CN(Cc2ccc(CCC(C)(C)O)cc2)CC(C)O1 +CC(=O)Nc1ccc(C(C)=O)cc1OCc1ccc2c(c1)OCO2 +O=C1CCCN1CCC(=O)N1CCN(CC(O)c2ccccc2)CC1 +CCOC(=O)c1sc(-c2csc(C)n2)nc1C +O=C(CCc1cccs1)N1CCC(c2nnc3n2CCC3)CC1 +COCc1nc(Cc2ccccc2OC)sc1C(C)(C)O +Cn1cnnc1CNS(=O)(=O)c1ccc(C(F)(F)F)nc1 +Cc1ccccc1C1(C(=O)Nc2ccc(CS(N)(=O)=O)cc2)CC1 +CCNC(=O)C1CCN(C(=O)c2cc(CC(C)C)nn2C)C1 +Cc1nc2ccccc2c(C)c1CC(=O)NCc1cccnc1 +CC(CN1CCOCC1)NC(=O)N1CCCC(NS(C)(=O)=O)C1 +CCC(C)(CC(=O)OC)NC(=O)c1cnc2ccc(C)cn12 +N#CCCN(Cc1ccccc1)Cc1cccnc1 +CCCCn1nc(C#N)cc1-c1ccc(OC)c(OC)c1 +Cc1ccccc1C1CC1C(=O)NCCCN1CC(C)OC(C)C1 +O=C(COC(=O)c1cccc(Cl)c1)NC1CCCc2ccccc21 +CC(CC(=O)Nc1ccc(-n2cnnn2)cc1)c1ccccc1 +CC(=O)Nc1c(C)nn(COc2ccc(F)cc2F)c1C +COc1ccccc1-c1noc(C(C)NC(=O)c2ccc(F)cc2)n1 +Cc1ccc(CNS(=O)(=O)c2ccc3c(c2)CCCC3)o1 +Cc1ccc(Oc2ncnc(N(C)C)c2N)cc1C +COC(=O)C(C)CN(C)S(=O)(=O)c1ccc(C)s1 +CC(C)CC1COCCN1C(=O)Cn1c(=O)[nH]c2ccccc2c1=O +COc1ccc(OC)c(C2CCN(C(=O)C3CCOCC3)C2)c1 +CC(=O)c1cccc(NC(=O)CSc2nnc(-c3ccco3)o2)c1 +CC(C(=O)N1CCN(C)CC1)n1sc2ccccc2c1=O +COc1ccc2c(c1)c(=O)c(C(=O)Nc1ccc(F)cc1)cn2C +CN(C)c1cncc(C2CCN(c3ncccn3)CC2)n1 +Cc1ccn2c(=NC(=O)Cc3cn(C)c4ccccc34)[nH]nc2c1 +O=C(c1cncs1)N1CCCC(c2ccncc2)C1 +Nc1[nH]ccc1C(=O)c1cccc(Br)c1 +CNC(=O)Cc1ccc(NCc2cc3ccccc3nc2OC)cc1 +CCCNC(=O)c1cc(S(=O)(=O)N2CCCC(C)C2)cs1 +CC(OC(=O)c1n[nH]c2ccccc12)C(=O)NCCc1ccccc1 +Cc1ccc(NC(=O)NC2CCCC2OCc2ccccc2)c(C)n1 +COCCOc1ncccc1C(=O)Nc1sccc1C#N +CCCCn1c(SCc2cc(=O)n3ccsc3n2)n[nH]c1=O +CCCC(C)N1CC(C(=O)NC2CCCn3nc(CC)nc32)CC1=O +COCCN(CC(C)C)C(=O)c1ccc(S(C)=O)cc1 +CN(CC1CC1)C(=O)Nc1ccccc1S(C)(=O)=O +CCc1ccc2nc(NC(=O)c3ccc4nnn(O)c4c3)sc2c1 +O=C(NCc1cccc(F)c1)c1nc(-c2cccc3[nH]ccc23)no1 +CCCn1nnnc1Cn1nnc(-c2cccc(C(F)(F)F)c2)n1 +Cc1cc(NC(=O)c2ccc(Oc3ccccc3)cc2)n(C)n1 +CC(=O)Nc1ccc(Cl)cc1NCc1nnc(C(C)(C)C)o1 +CNc1ncnc(Sc2ccc(Cl)cc2)c1N +CCCc1cc(C(=O)NC(C)c2ccc(OC)c(F)c2)n(C)n1 +Cc1nc(SC2CCCCNC2=O)n(CC2CCCO2)c1C +O=C(CSc1ccc(F)cc1F)N1CCC(CO)C1 +Cn1ccc(CNC(=O)Nc2ccc(S(=O)(=O)C(F)F)cc2)c1 +CCc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)s1 +CCc1noc(C2CCCN(C(=O)NC3CCCCC3)C2)n1 +COc1ccc2c(c1)oc1c(-c3ccncc3)c(C#N)c(N)c(C#N)c12 +Cc1cc(C)n(C(C)C(=O)NC2(c3ccccc3)CCCC2)n1 +O=C(c1c[nH]c2ccccc12)N1CCN(Cc2ccccc2)CC1 +Cc1noc2ncc(NC(=O)c3cnc(-c4ccsc4)s3)cc12 +CNC(=O)N1CCC(c2cc(-c3ccc(F)cc3)n[nH]2)CC1 +COCCCCNc1cc(F)c(Br)cc1F +Cc1n[nH]c(-c2ccc(NCc3c[nH]nc3-c3ccccc3)cc2)n1 +COC(=O)c1ccc(NCCNC(C)=O)c(N)c1 +CC(=O)Nc1cccc(NCC(=O)Nc2cccc(C)c2C)c1 +Cc1cc(-c2nnc(NC(=O)C(C)(C)C)o2)nn1C +CC(C)n1nccc1-c1nnc(NC(=O)c2ccc(Cl)cc2)o1 +NC1=NC(=O)C2(CCN(C(=O)c3cn4ccsc4n3)CC2)N1 +CC(C)n1c(C2CCCN(C(=O)c3cccnc3)C2)nn(C)c1=O +Cc1nc(C)c(C(=O)N2CC3CC4CC(C3)CC2C4)s1 +CCn1nc(C(=O)Nc2nnc(-c3cccc(C)c3)o2)cc1C +Cc1ccccc1NC(=O)Cc1nc(Cn2cnc(C#N)n2)cs1 +CC(C)(C)OC(=O)N1CC=C(c2ccc3c(c2)NC(=O)C3)CC1 +COc1cc(OC)c(CNC(=O)c2ccncc2F)c(OC)c1 +COC(=O)C1CCc2c(nc(CC(F)(F)F)n2C2CC2)C1 +Cc1nc2cc(NC(=O)c3ccnc(-n4cncn4)c3)ccc2o1 +COC(=O)c1cc(CN(C)C(=O)c2ccoc2C)oc1C +COCC1CCCN(C(=O)CCc2c(C)noc2C)C1 +Cc1ccc(-c2cc(CNC(=O)c3ccccc3F)on2)cc1 +Cn1ccnc1SCC(=O)Nc1ccc(C(F)(F)F)cn1 +Cc1cc(NC(=O)C2CC2)sc1C(=O)NCc1ccc(F)cc1 +COc1ccc(-c2nc(NC(=O)c3ccncc3)sc2C)cc1 +CCOCc1cccc(S(=O)(=O)Nc2cccc(C(=O)NC)c2)c1 +CCS(=O)(=O)NCCNC(=O)N1CCc2ccccc2C1 +Cc1nnnn1-c1ccc(C(=O)N2CCC(c3ccccc3)CC2)cc1 +COc1ccc2c(CC(=O)NCCOc3ccccc3)coc2c1 +O=C(Cc1cccc(F)c1F)NCc1cccc(-c2nc[nH]n2)c1 +COC(=O)c1ccc(C(=O)Nc2cnc3c(cnn3C(C)C)c2)cc1 +COc1ccnc(NC(=O)c2nccc3ccccc23)c1 +CCC(CC)c1cc(CNC(=O)c2cnc3ccc(C)cn23)on1 +O=C(NC1CCN(c2ncccn2)CC1)c1ccc2c(c1)OCCO2 +COc1cc(C#N)ccc1OCC(=O)N(C)Cc1cccc(F)c1 +Cc1cc(NC(=O)Cc2c(C)nc(-c3ccccn3)[nH]c2=O)[nH]n1 +Cc1cc(C(=O)N2CCCCCC2c2ccco2)c2c(C)noc2n1 +c1ccc2c(c1)CCC2Nc1nncc(-c2ccc3c(c2)OCO3)n1 +CC(=O)N(C)c1ccccc1NC(=O)Cc1cccc(F)c1F +COC(=O)C1CCCCCC1NC(=O)Nc1cc(C)on1 +CCOC(=O)CCCNC(=O)N1CCc2cc(F)ccc2C1 +Cc1ccccc1CCCNC(=O)c1cc(C#N)c[nH]1 +O=C(NC1CCC(O)CC1)NC1CCCN(c2ccccc2F)C1=O +CCCn1ccc2ccc(NC(=O)Nc3c(C)n[nH]c3C)cc21 +COc1ccc(OC)c(-c2csc(N(C)C(=O)c3ccco3)n2)c1 +O=S(=O)(c1c[nH]cn1)N1CCCC(Cn2cncn2)C1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1ccccc1C +COCc1cccc(C(=O)Nc2ccc(N3CCOCC3)nc2)c1 +CC(C)N(C)C(=O)NC1CC(=O)N(CC(F)(F)F)C1 +COC(=O)c1ccc(C(C)(C)C)cc1C(=O)OC +Cc1cccc(NC(=O)N2CCOCC2C2CC2)c1Cl +CCOc1cc(F)ccc1NC(=O)c1cccc(S(C)(=O)=O)c1 +Cc1ccc(NC(=O)CSc2nncn2C(C)C)cc1C +CCc1nn(-c2ccc3ccccc3n2)c2c1CNCC2 +C=CCNC(=O)c1cnn(-c2ccc(Cl)cc2)c1C(F)(F)F +Cc1noc(C2CCN(C(=O)CCNS(C)(=O)=O)CC2)n1 +COc1ccc(OC)c(NCC(=O)NC(C)c2ccccc2)c1 +Cc1ccc(S(=O)(=O)NC(C)c2ccco2)cc1 +Cc1nnc(-c2cccc(C(=O)OC(C)c3cccc(C#N)c3)c2)o1 +CC(=O)Nc1ccc(NC(=O)Cc2ccccc2)cc1 +Cn1c(=O)[nH]c(=O)c2c1nc1n(CCO)c(-c3ccccc3)cn21 +CCC1(c2nc(-c3ccncc3)no2)CCN(C(=O)OC(C)(C)C)C1 +Cc1cc(=O)c(C2NCCc3cccc(C)c32)c[nH]1 +CC(CC#N)N(C)C(=O)Nc1cccc(Cn2ccccc2=O)c1 +COc1ccc(N)c2c(C(=O)Nc3ccnc(C)c3)nccc12 +CSc1nc(C(C)C)nc(C)c1C(=O)NCc1ccccc1Cl +Cc1nc2cc(C(=O)NCCC3=CCCCC3)ccc2n(C)c1=O +OCc1c(-c2ccco2)nc2sc(-c3cccc(F)c3)nn12 +Cc1cc(C)c(C(=O)N2CCC(O)(c3cccnc3)CC2)c(=O)[nH]1 +CCc1ncc(C(=O)NC(C)c2ccccc2)c(N)n1 +O=C(CCOc1cccc2cccnc12)n1ccnc1 +Cc1ccc(C(CNC(=O)CC(C)C)N2CCOCC2)cc1 +O=C(COc1ccccc1)Oc1nc2ccccc2o1 +O=C(CC1CC2CCC1C2)NCCOc1ccccc1 +CC1(C)Cc2ccccc2C2=NC(CN3CCCCC3)=NC(=O)C21 +CCCCC1C=CCN1C(=O)c1ccc(C)c(N2CCNC2=O)c1 +Cc1cc(C)c(NC(=O)CN(C)S(N)(=O)=O)c(C)c1 +NC(=O)c1ccc(NC(=O)CCS(=O)(=O)c2ccccc2)cc1 +Cc1c(C#N)c(N)n(CCOCC(F)(F)F)c1C +Cc1ccc(CN2CCN(C(=O)c3cnc(C)cn3)C(C)C2=O)cc1 +CCc1ccc2c(COC(=O)C(C)NC(C)=O)cc(=O)oc2c1 +CC(=O)N1CCc2ccc(NC(=O)c3c(C)cc(C)cc3C)cc2C1 +Cc1nn(C)c(=O)c(C(=O)NCC(C)Oc2ccccc2)c1C +Cc1ccc2[nH]nc(C(=O)NCc3ccc(C)c(F)c3)c2c1 +CCN(CC)S(=O)(=O)c1ccc2[nH]c(=O)n(C)c(=O)c2c1 +COc1ccc(NC(=O)C(C)n2cnc3ccccc3c2=O)cc1 +Cc1cc(N2CCC(c3ncncc3S(C)(=O)=O)CC2)ncn1 +CC(=O)Nc1ccc2c(COC(=O)C3CCCO3)cc(=O)oc2c1 +CCOc1cc2c(cc1NC(=O)Nc1cccnc1)OC(C)C2 +Cn1ccc(NS(=O)(=O)c2ccccc2C#N)n1 +Cc1nnc(CNC(=O)c2cc(C(C)C)oc2C)o1 +CCC(=O)Nc1cccc(C(=O)OCc2cccc(C(N)=O)c2)c1 +COc1cccc(SCC(=O)N2CC(=O)Nc3ccccc32)c1 +COc1cccc(Cc2nc(-c3ccc(N)cc3)cs2)c1 +C=CCn1c(N)nnc1SCc1ccc(C(F)(F)F)cc1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)N2CC(C)CC(C)C2)c1 +COc1ccc(NC(=O)c2cc(F)ccc2-n2cnnn2)c(OC)c1 +Cc1ccn2cc(C(=O)Nc3ccccc3CN3CCNC3=O)nc2c1 +Cc1occc1C(=O)Nc1ccccc1N1CCC(O)CC1 +CC(CNC(=O)Nc1ccccc1Cn1cncn1)c1nccs1 +CC(C)c1noc(CCc2ccc(Cl)c(N)c2)n1 +CCOC(=O)c1cnc2ncnn2c1-c1ccc(OC)cc1 +c1csc(-c2nc(CSc3nnnn3C3CCCC3)co2)c1 +O=C1NC2CCCC1CN(Cc1c(F)cccc1Cl)C2 +Cc1cnc(C(=O)NCc2ccc(C(=O)N3CCCC3)cc2)cn1 +CCOc1ccc(C2=Nn3c(nnc3-c3cccnc3)SC2)cc1 +O=C(Cn1cnnn1)Nc1ccc(F)cc1OCC1CC1 +CNC(=O)c1nsc(C(=O)N2CC(C)CC(C)C2)c1N +CCOC(=O)C1CCN(c2nc3ccc(C)cc3n3nnnc23)CC1 +C=CCNc1nc(C)c(S(=O)(=O)c2ccc(N)cc2)s1 +Cc1ccc2c(CC(=O)NCc3ccccc3)coc2c1 +O=C(NCCCC(=O)N1CCCc2c(F)cc(F)cc21)c1ccco1 +Cc1ccc(NC(=O)c2nnc(COCC(=O)NC3CC3)s2)cc1 +CN1CC(NC(=O)c2cccc(Cl)c2)CCC1=O +O=C(Nc1ccc2c(c1)OCO2)N1CCCC1c1ccco1 +COCc1nc2ccccc2n1Cc1ccc(C#N)cc1 +COc1cccc2c1ccn2CC(=O)N1CCCCCC1 +COc1ccccc1Nc1ccc2c(c1)CCN2C(C)=O +CCc1nc(C)ccc1OCC(=O)N(C)Cc1cccc2cnccc12 +COc1cccc2c(=O)c(C(=O)Nc3cccc(C)n3)cn(C)c12 +CC(OC(=O)c1cnccn1)C(=O)Nc1ccc(C(N)=O)cc1 +O=C(CNC(c1ccccc1)C(F)(F)F)NC1CCC(O)CC1 +CN(CC1CCCO1)C(=O)NCc1cc(F)ccc1Br +Cc1ccc(C)c(NC(=O)C2CC(=O)N(Cc3ccccc3)C2)c1 +Cc1ccc2nc(SCCC3OCCO3)nc(=O)n2c1 +O=C1COc2cccc(OCC#Cc3ccc(F)cc3)c2N1 +CC(C)(C)OC(=O)N1CCC(CO)(c2ccccn2)CC1 +CN(Cc1ccco1)C(=O)CCn1ncc(=O)c2ccccc21 +Cc1ccccc1C1CN(Cc2cnc3ccc(C#N)cn23)CCO1 +Cc1cc(F)ccc1S(=O)(=O)NCc1ncc(-c2ccccc2)o1 +CC(C)(C)OC(=O)N1CCC(=O)C(CCO)CC1 +COc1cc(N2CC(C(=O)N3CCCC3)CC3OCCC32)ncn1 +CCC(CO)NC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +Cc1ccc(CNc2c3c(nc4ncnn24)CCCC3)cc1 +CC(=O)N1CCCN(C(=O)c2cc(C3CC3)on2)c2ccccc21 +O=C(CCn1cncn1)Nc1ncc(Cc2ccc(F)cc2F)s1 +CCn1c(=O)n(Cc2noc(C3CC3)n2)c2ccccc21 +Cc1cc(C)cc(OCC(=O)N(CCO)C(C)C)c1 +CC(=O)N(C)c1nc(CN2CCOC(c3nc(C)n[nH]3)C2)cs1 +COCCNS(=O)(=O)c1cnn(C2CCCC2)c1N +O=C(NCCc1ccccn1)NC1(c2ccccc2)CCC1 +CCc1noc(CN(C)C(=O)c2cc(F)cc(Cl)c2O)n1 +CC(=O)c1cccc(OC(=O)c2cnn(C)c2C)c1 +COc1ccccc1NCC(=O)NCCC(C)C +Cc1nn(C)c(C)c1NC(=O)C(C)Sc1cccc(Cl)c1 +CC(C)N1CCN(C(=O)c2ccnc(-n3cncn3)c2)CC1 +Cc1cc(C(C)NC(=O)Nc2ccccc2C)c(C)o1 +CCc1c(C)nc2n(c1=O)CC(C(=O)Nc1cnccc1C)CS2 +Cc1nnc2sc(-c3ccc(O)cc3)nn2c1=O +CCC1(CO)CCCN(c2cncc(N(C)C)n2)C1 +Cc1csc(C(C#N)C(=O)CCOc2cccc(C)c2C)n1 +O=C(Nc1ccc(N2CCCC2=O)c(Cl)c1)C1CC=CCC1 +Cc1ccc2nc(C(=O)Nc3ccccc3)oc2c1 +COCCN(C)S(=O)(=O)c1cccc(-n2cnnn2)c1 +O=C(C1CCC1)N1CC2CN(Cc3ccncc3)C(=O)C2C1 +O=C(c1ncccn1)N1CCC2OCCC2(COc2cccnc2)C1 +Cn1nnnc1SCC(=O)Nc1ccccc1N1CCNC(=O)C1 +COc1cc(C)ccc1NC(=O)c1ccc(-n2nc(C)cc2C)cc1 +Cc1cc(-c2nnn(CC(=O)NCC(C)C)n2)ccc1F +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)N(C)Cc1ccccc1 +Cc1cc(CN(C)C(=O)c2ccccc2S(=O)(=O)C(C)C)no1 +CCCC(C)(CO)NC(=O)NCCc1ccc(Cl)cc1 +Cc1ccc(NC(=O)COC(=O)CC(C)c2ccccc2)c(C)c1 +CC(C)Sc1nc(COc2ccc(Cl)cc2)n[nH]1 +CCOc1cc(C)ccc1NC(=O)NCCCc1c(C)noc1C +CC(NCc1cnc(N2CCOCC2)nc1)C(C)n1cccn1 +CCN(C(=O)CS(=O)(=O)c1nc2ccccc2[nH]1)c1ccccc1 +CS(=O)(=O)N1CCCC(C(=O)Nc2cccc(Cl)c2)C1 +OCCN(Cc1cccnc1)Cc1ccnc2ccc(Cl)cc12 +CCOC(=O)c1cnn2ccc(NC(=O)c3ccc(C)cc3)cc12 +O=C(NCC(=O)N1CCN(c2nccs2)CC1)c1ccc(F)cc1 +O=C(Nc1ccc2ccccc2c1)N1CCCC(O)C1 +Cn1nnc2c(N3CCN(CC(=O)N4CCCCC4)CC3)ncnc21 +Cc1ccoc1C(=O)Nc1ccc(Cl)c(N)c1 +CC(C)C(C)(C#N)NC(=O)C1CCCN(CC(F)(F)F)C1 +CCOC(C)C(=O)Nc1ccc(F)c(NC(=O)Cc2ccccc2)c1 +Cc1nc2ccccc2n1NC(=O)NCC(F)(F)F +O=C(CNC(=O)c1ccc(C(F)(F)F)cc1)NCc1ccoc1 +COCCOCC(=O)Nc1cccc(-c2cnco2)c1 +Clc1ccc(Br)cc1OCc1nnc(C2CC2)o1 +CCc1cccc(OC2CN(C(=O)c3cnccc3C)C2)c1 +COc1cccc(CC(=O)Nc2ccc(Br)cc2O)c1 +COC(=O)C(NCc1nc2ccccc2s1)C(C)C +C=CCN(C)C(=O)c1ccc(Oc2ccc(OC)cc2)cc1 +CCn1nc(-c2c(C)cc(C)cc2OC)cc(CC#N)c1=O +CN(C)c1ccc(-c2nnc(SCC(=O)NC3CC3)n2C)cc1 +COCCCSc1nc2cc(F)c(F)cc2[nH]1 +CC1CCC(NC(=O)Nc2cccc(Cn3cccn3)c2)CC1 +O=C(CC1CC1)NC1CN(c2ncccn2)C2COCC12 +COc1cc(C(=O)N2CCCCC2C)cc(OC)c1OCC(N)=O +Cc1ccccc1C1CC(C)N(Cc2cnnn2C)C1 +Cc1cccc(OCCCC(=O)N2CCC(CC(N)=O)CC2)c1 +Cc1nc(C2CCCN2C(=O)Cc2c(C)nn(C)c2C)no1 +CCNC(=O)NC(C)c1ccc(Cl)cc1Cl +Cc1cccc(C(=O)NCC(=O)NCCN(C)c2ccccc2)c1 +COc1ccc(Cl)cc1NCC(=O)N1CC(=O)Nc2ccccc21 +CN(Cc1cnn(-c2ccccc2)c1)Cc1nc2ccccc2c(=O)[nH]1 +N#CCCN(CC1CC1)C(=O)c1nc(C2CC2)n(-c2ccccc2)n1 +Cc1csc2nc(CSc3nnc(-c4ccco4)o3)cc(=O)n12 +Fc1cc2c(cc1Cl)C(C1CCOCC1)NCC2 +O=C(Cc1ccc(Cl)cc1)N1CCC(O)CC1 +CCn1cc(C(=O)NC2CCCCCC2)c(=O)c2ccc(C)nc21 +CC(O)C1CCCN(C(=O)C(O)c2cc(Cl)cc(Cl)c2)C1 +Nc1cccc(-c2n[nH]c(-c3cccc(Br)c3)n2)c1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)CCn1cncn1 +CCc1nc(NC(=O)c2cc(OC)c(OC)c(OC)c2)sc1C +CC(C)(NC(=O)Cn1c(=O)cnc2ccccc21)c1cccc(F)c1 +CCN(CC(=O)N1CCN(C(C)=O)CC1)c1ccccc1 +CN(C)C(CC#N)COc1cccc(Br)c1 +COc1ccc(CN(C)C(=O)c2ccc3[nH]cnc3c2)cc1 +CC(Oc1ccc2c(c1)OCO2)c1ccnc(N)n1 +CCCN(CC(=O)OC)S(=O)(=O)c1ccc(F)c(Cl)c1 +COc1ncccc1C(=O)NCC#CCOc1cccc2cccnc12 +c1ccc(-c2nccc(N3CCN(Cc4cc[nH]n4)CC3)n2)cc1 +CCCC(=O)N1CCCCC1C(=O)NCCc1cccnc1 +CCC1CN(CC(=O)N2CCC(C)CC2)c2cc(C(C)=O)ccc2O1 +CC1CN(C(=O)Nc2ccc(-n3cnnn3)cc2)CC(C)O1 +CC(OC(=O)Cc1coc2cc3c(cc12)CCC3)C(=O)N1CCCC1 +OC(c1ccc2c(c1)COC2)c1cc(Cl)ccc1F +CCc1nc(NC(=O)c2cc(C(C)C)nc3onc(C)c23)sc1C +COc1ccc(Br)cc1-c1[nH]nc(C)c1C +Cc1n[nH]c(SCC(=O)Nc2ccnc3ccccc23)n1 +N#Cc1ccc(C(N)c2nnc(-c3cncnc3)o2)cc1 +COc1ccc(CNC(=O)c2cc(N)ccc2Cl)cc1 +Cc1cc(CN(C)C(=O)C(C)Sc2ccccc2Cl)no1 +Cc1cc(NC(=O)CNC(=O)c2cc(-c3ccccc3)on2)n(C)n1 +CCOC(=O)c1cnc(-c2ccc(OC)cc2)nc1C +CC1(C)COC(=O)C1OC(=O)Cn1cc(Br)ccc1=O +Nc1cccc(CN(C(=O)c2cc[nH]n2)C2CC2)c1 +CC(CO)NC(=O)COc1cccc(C(C)C)c1 +CS(=O)(=O)c1ccc(SCCC(=O)Nc2ccccc2)cc1 +COc1cc2ncc(C#N)c(Nc3ccc4c(c3)OCO4)c2cc1OC +COc1ccc2c(C(=O)CN3CCN(c4ccccc4)CC3)c[nH]c2c1 +c1ccc2c(c1)nc1n2CN(n2cnnc2)CN1n1cnnc1 +CC=CCC(=O)N(CC)Cc1ccc(Cl)cc1 +COCC(=O)Nc1ccc(-c2nc3ncccc3o2)cc1 +CC(=O)N1CCC2(CC2C(=O)Nc2cccnc2)C1 +O=C(Nc1nccs1)c1ccc(F)cc1-n1cnnn1 +CCOC(=O)c1cc(-c2cc(C)ccc2C)nn1C +CC(C)n1c(-c2ccc(Cl)cc2)ccc(CO)c1=O +Cc1nn(-c2ccccc2)c(C)c1CCC(=O)N1CCNC(=O)CC1 +CCCOc1ccc(-n2nnc(C(=O)Nc3nccs3)c2C)cc1 +Cc1cc2c(s1)C(c1ccccc1)=NCC(=O)N2C +COc1ccc(OCC(=O)N2CCN(c3ncccn3)CC2)cc1 +CCCNC(=O)CNC(=O)CSc1cc(Cl)ccc1Cl +CN(C)c1ccc(NC(=O)C2CCCN(C(=O)c3ccco3)C2)cn1 +CC(CS(=O)(=O)c1ccc(F)cc1)C(=O)NC1CCCNC1=O +Cn1cnnc1SCc1c(F)cccc1Cl +CCc1cccc(NC(=O)N2CCN(C(=O)c3ccoc3)CC2)c1 +CC(=O)Nc1cccc(NC(=O)c2c(C)cccc2N)c1 +CS(=O)c1ccc(C(=O)N2Cc3ccccc3CC2C(N)=O)cc1 +COC(=O)c1cc(-c2ccc3ccccc3c2)[nH]c1N +CNC(=O)c1ccnc(CC2COc3cc(OC)ccc3C2)c1 +CCCOc1cccc(-c2ccc(CC#N)c(=O)n2C)c1 +CC(NS(=O)(=O)c1cn[nH]c1)c1cccs1 +CCOC(=O)c1cc(-c2cc(Br)ccc2F)nn1C +Cc1cc[nH]c(=NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)c1 +CC(Sc1nnnn1C1CC1)C(=O)Nc1ccc(C#N)c(Cl)c1 +O=C(CCc1[nH]nc2c1CCCC2)NCCn1nnc2ccccc21 +COc1cc(N2CCC3(CCCN(C4CCCCC4)C3=O)C2)ncn1 +CN(CCO)c1ncnc2scc(-c3ccc(Cl)cc3)c12 +COc1ccc(-n2ccnc2C(C)Cc2ccc3c(c2)OCO3)cn1 +Cc1ccc(NC(=O)CCNC(=O)CNC(=O)c2ccccn2)nc1 +COc1cc(Cl)c(C(=O)C2COCCO2)cc1OC +C=C(C)COc1cccc(NC(=O)N(C)CC2(CO)CCOCC2)c1 +Cc1ccc(C)c2sc(N(C)CC(=O)NCc3cccnc3)nc12 +CCn1nc(C)c(C(=O)N2C3CCC2CN(C)C(=O)C3)c1C +Cc1csc(CNc2ccc3oc(C4CC4)nc3c2)n1 +Cc1ccc(N2CCC(C(=O)N3CCNC(=O)C3)C2=O)cc1C +COc1ccc(CCNc2nc(=O)[nH]nc2C)cc1 +CN(CCN(C)C(=O)C1(c2ccccc2)CC1)C(=O)OC(C)(C)C +O=C(Cn1nc2ccccn2c1=O)NCCC1=CCCCC1 +COc1cc(NC(=O)c2c(OC)cccc2OC)cc(OC)c1 +CN(Cc1ccc(Cl)cc1)c1nc(N)nc2[nH]cnc12 +CC(C)CNC(=O)CNC(=O)c1cc2occ(-c3cccnc3)c2[nH]1 +CCCn1nccc1NC(=O)c1cnn2c(-c3ccccc3)ccnc12 +COc1cccc(CC(=O)NCC(=O)Nc2cccc3cccnc23)c1 +Cc1nc(SCC(=O)N2CCCCC2)c2c(C)c(C)sc2n1 +N#Cc1cccc(NC(=O)C2CN(S(=O)(=O)C3CC3)C2)c1 +COc1ccc(-c2nc(C#N)c(N3CC(C)OC(C)C3)o2)cc1 +Cc1ccccc1NC(=O)C(C)Oc1ccc(-n2cnnn2)cc1 +CN(CCC(F)(F)F)C(=O)c1ccc(-n2cccn2)cc1 +Cc1ccc(OC2CCN(C(=O)OC(C)(C)C)C2)cn1 +CCOc1ccccc1OCCN1CCCS1(=O)=O +CCOC(=O)c1nnn(-c2ccc3c(c2)OCO3)c1N +Cc1c(C(=O)N2CCc3ccccc3C2C)cnn1-c1ccncc1 +COC(=O)CN(C(=O)c1cccc(F)c1F)C(C)C +COC(=O)CNC(=O)c1sc2nc(C(C)(C)C)nc(C)c2c1C +Cc1cccc(NC(=O)CC(C)c2c(C)n[nH]c2C)c1O +CCNC(=O)Cc1ccc(-n2ccnc2-c2cccnc2)cc1 +CC(CC#N)Sc1ccccc1NC(=O)NCc1ncc[nH]1 +O=C(CCNC(=O)NCc1ccc(Cl)cc1)NC1CCCC1 +CCc1ccc(C(=O)OCCNC(=O)c2ccncc2)o1 +O=C(c1csc2ccccc12)N1CCCCCC1 +CC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)c2cccs2)c1C +CCn1ncc2c(C(=O)OCCOC)cc(-c3ccccc3)nc21 +CCCn1nc(C(=O)N(C)Cc2ccc3c(c2)OCO3)ccc1=O +Cc1cccc2[nH]cc(CC(=O)N3CCN(C4CCCC4O)CC3)c12 +COC(=O)c1sc(=NC(=O)c2c[nH]c3ccccc3c2=O)[nH]c1C +COc1ccccc1OCC(=O)Nc1ccnn1Cc1ccco1 +CC(C)CCC(C)(O)CNC(=O)NCC1CC=CCC1 +COc1ccc(OCCCC(=O)Nc2ccc(F)c(C#N)c2)cc1 +CCOC(=O)C1=C(C)C(C(=O)NC(C)CC)C(C)=N1 +C#CCNC(=O)CNC(=O)Nc1ccc(S(=O)(=O)C(F)F)cc1 +COc1ccc(OCCS(=O)(=O)N=c2[nH]cccc2C)cc1 +Cc1ccc(SCCC(=O)N2CCOCC2)cc1C +Cc1ccc(Cc2nnc(-c3ccc(N)cc3Cl)o2)cc1 +CC(C)n1ccc(-c2nnc(NC(=O)c3ccnn3C(C)C)o2)n1 +COc1ccc(N)cc1NC(=O)CCCN1CCOC1=O +Cn1c(=O)n(CC(=O)NCc2cccs2)c2cncnc21 +CCc1ccc(NC(C)C(=O)N2CCN(C(C)=O)CC2)cc1 +Cc1ccc(-n2c(C)nc3ccsc3c2=O)cc1 +C=CCCC(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +COc1ccc(NC(=O)c2cc[nH]n2)c2cccnc12 +O=C(CNS(=O)(=O)c1ccc(F)c(Cl)c1)NCc1ccco1 +CNC(=O)Nc1ccc(C)n(CC(=O)NCc2ccccc2C)c1=O +COc1cccc(C(=O)Nc2ccnc3[nH]ncc23)c1 +C=CCN1CCC2(CCN(C(=O)c3cnc(C)cn3)CC2)C1=O +O=c1c2ccsc2ccn1CC(O)c1ccccc1F +O=c1nc2n(-c3ccccc3F)c3ccccc3cc-2c(=O)[nH]1 +Cn1c(C(N)c2ccc(Cl)cc2)nc2ccccc21 +Cc1cc(C)n(Cc2cccc(C(=O)NCCCn3cncn3)c2)n1 +CC(Sc1ccc(Br)cc1)C(=O)NC1CC1 +CC(=O)N1CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +Cc1ccc(C(=O)Nc2ccc3nc(-c4cccc(F)c4)[nH]c3c2)cn1 +CN1CCC(Nc2ccc3cccc(Br)c3n2)C1=O +CCn1cc(-c2cc(C(F)(F)F)n3nccc3n2)c(C)n1 +COc1ccc(NC(=O)NCCC(=O)Nc2cc(C)cc(C)c2)cc1 +CC1CC(C)(C)C(CNC(=O)c2ccon2)C1NC(=O)c1ccon1 +Cc1ccc(NC(=O)N(Cc2ccsc2)C2CC2)cc1 +COc1ccccc1CN1CC(C(=O)N2CCCOCC2)CC1=O +CCN1CCN(C(=O)C2(c3ccccc3Cl)CC2)CC1 +Nc1cc(Cl)c(Cl)cc1NC(=O)c1cccs1 +OCC1COCCN(c2ncnc3sccc23)C1 +COc1cc(C(=O)N2CCCC(c3ccn[nH]3)C2)ccc1C +CCCC(=O)N1CCC(C(=O)Nc2ccc(C#N)cc2)CC1 +COc1ccc(F)c(NC(=O)C(C(C)C)N2CCCC2=O)c1 +CNC(=O)Nc1ccccc1SC1CCCC1 +O=C(NC1CCCC1)c1nc(CC(=O)N2CCOCC2)no1 +N#Cc1cccnc1N1CCN(S(=O)(=O)c2cccnc2)CC1 +COc1ccc(Cl)cc1NC(=O)Cn1ncccc1=O +CC(NC(=O)c1cc(-c2ccncc2)nc2ccccc12)c1ncn[nH]1 +Cc1cccc(CNCC(O)c2ccccc2F)c1C +Cc1ncc(CNC(=O)c2ccnc(OC3CCC3)c2)s1 +Cn1cnnc1SCc1csc(-c2ccc3c(c2)OCO3)n1 +CSc1ccc(CN(C)C(=O)c2ccccc2O)cc1 +CC1CCN(C(NC(=O)c2cccs2)C(=O)c2ccccc2)CC1 +COc1ccc(O)c2c1C(c1ccc(O)cc1)NCC2 +Cc1cc(C)n2nc(CC(=O)NC(C)c3cc(C)sc3C)nc2n1 +O=C(NCC1(C2CC2)CC1)c1cccc(OCC(F)F)n1 +COc1ccccc1CNC(=O)c1cc(C2CC2)on1 +COC(=O)N(C)c1ccc(NC(=O)NCc2cnc(C)s2)cc1 +CCOc1cccc2cc(C(C)NC(=O)NCC3CCCO3)oc12 +COc1ccc(C(=O)NCC#CCOc2ccc3cccnc3c2)cc1 +Cc1ccc(O)c(C(=O)N2CCCC(C(N)=O)C2)c1 +Cc1cc(N(C)Cc2c(C)noc2C)n2nc(C)c(C)c2n1 +O=C(NCC1(c2ccccc2)CCOCC1)C1CC2CCC1C2 +Cc1ccccc1OCC(=O)Nc1ccc2c(c1)ncn2C +Cn1ccc(C(=O)Nc2cccc(Cl)c2Cl)n1 +Cc1nn(C)c(C)c1CC(=O)Nc1nc(-c2ccccc2)cs1 +Oc1cc(CSc2ncccn2)nn1-c1nc2ccccc2[nH]1 +COc1ccccc1CC(=O)Nc1nnc(-c2ccncc2)s1 +Cc1cc(Br)ccc1C(=O)N1CCOCC1C1CC1 +CC(C)N(CC(F)(F)F)c1ccc(N)cc1Cl +O=S(=O)(c1ccc2c(c1)OCO2)N1CCCCC1CO +Cn1cc(C(=O)Nc2ccn(CC(F)(F)F)n2)c(C(C)(C)C)n1 +CC(C)c1nc(C(C)NC(=O)c2ccn(-c3ccccc3)n2)cs1 +NS(=O)(=O)c1cc(Cl)c(NC(=O)CO)c(Cl)c1 +COCCn1c(C)cc(C(=O)Cn2nnc(-c3cccs3)n2)c1C +CCN(c1ccc(N)c(OC)n1)c1ccccc1C +Cc1ccc(N2CCOC2=O)cc1NC(=O)Cc1c(F)cccc1F +Cc1cc(C(=O)NCC2CCN(c3ncccc3C(N)=O)CC2)on1 +CC(NC(=O)c1ccc(-n2cncn2)nc1)c1ccc2ccccc2c1 +CC(C)CNC(=O)c1ccc(N2C(=O)CCS2(=O)=O)cc1Cl +c1cc2nnc(C3CCC3)n2nc1N1CCOCC1 +C#CC(CC)(CC)NS(=O)(=O)c1ccc(F)cc1 +CC(C)NC(=O)c1ccc(NC(=O)CNc2ccccc2F)cc1 +Cc1cc(C(C)Nc2nnc(C)c(C)c2C#N)c(C)o1 +CCC(=O)Oc1ccc2cc(C(=O)NCC3CCCO3)c(=O)oc2c1 +CC(C)NC(=O)c1cc2c(s1)CCN2C(=O)c1ccc(F)cc1 +Cc1cc(CNCC(O)c2ccco2)ccc1-n1cncn1 +Cc1ccc2c(CC(=O)NCc3nc(C)sc3C)c[nH]c2c1 +O=C(C1Cc2ccccc2O1)N1CCc2[nH]nc(-c3ccno3)c2C1 +CC(C)C(=O)NCCNC(=O)C1CCN(S(N)(=O)=O)CC1 +C#CCNC(=O)CCc1ncc(-c2ccc(OC)cc2)o1 +Cc1ccc(-c2noc(CSc3nnc(C)c(=O)n3N)n2)cc1F +O=C(Nc1nnc(Cc2cccc(F)c2)s1)C1CC=CC1 +Cn1cc(CCC(=O)NC2c3ccccc3Oc3ccccc32)cn1 +CCSc1ncc(Cl)c(C(=O)Nc2nc(C)cs2)n1 +Cc1cccc(NC(=O)C2CC(=O)N(c3ccc4c(c3)OCO4)C2)n1 +CC(NC(=O)c1ccoc1)C(=O)Nc1cc(C(F)(F)F)ccc1O +COc1cc(C#N)ccc1OC(=O)C1COc2ccc(F)cc2C1 +CCC(C)(C)NC(=O)CN(C)S(=O)(=O)c1cccs1 +COc1ccccc1OCCN(C)Cc1cnc2nc(C)cc(C)n12 +COC(=O)C1CCN(C(=O)Nc2ccc(F)cc2Cl)CC1 +COC(=O)CCN(Cc1nc(C)cs1)C1CCOCC1 +CN(C)c1ccc(C#CCNC(=O)c2cc(-c3ccco3)n[nH]2)cc1 +O=C(NCc1cccnc1)c1cnc2sc3c(n2c1=O)CCCC3 +COCc1nnc(-n2nnc(CO)c2-c2ccco2)s1 +O=C(Nc1ccccc1Br)c1cc2c([nH]c1=O)CCCC2 +Cc1ccc(CN2CCN(S(=O)(=O)c3ccc(C)cc3)CC2)cc1 +CCNC(=O)c1ccc(NC(=O)c2cccs2)cc1 +COc1ccc(-c2noc(CCC(=O)NCc3cccs3)n2)cc1 +Cc1cc(C(=O)NC2CCN(S(C)(=O)=O)CC2)n(C)n1 +Cc1ccc(NC(=O)C2CC(=O)N(C3CCOCC3)C2)c(C)c1 +CCc1nc(C2CCCN2C(=O)c2ccc(NC3CC3)nc2)no1 +Cc1ccc(C(=O)NC(C)c2cc(C)oc2C)c(=O)[nH]1 +Cc1noc(C2CC3OCCC3N(Cc3sccc3C)C2)n1 +CCNc1nc(-c2sc(C)nc2C(C)C)cs1 +O=C(c1cccc(N2C(=O)CCS2(=O)=O)c1)N1CCCCC1 +CN1CC(NC(=O)Nc2cc(CC(C)(C)C)nn2C)CCC1=O +CCN(C(=O)NCc1cc(C)on1)C1CCN(c2ccccc2)C1=O +COC(=O)CCC(=O)NC1CCC(C)(C)c2ccccc21 +O=C(c1ccccc1NS(=O)(=O)c1cccc(F)c1)N1CCCC1 +CC(O)Cn1c(C(C)C)nc2ccc(Cl)cc21 +CS(=O)(=O)c1nsc(NC(=O)Cc2ccccc2)n1 +CCCNC(=O)c1ccc(NC(=O)N2CCNC(=O)C2)cc1Cl +Cc1nc(COc2ccccc2C(C)C)[nH]c(=O)c1CCO +COc1ccc(Cl)c(NC(=O)c2cscn2)c1 +O=C(Cn1c(=O)[nH]c2ccccc21)Nn1cnc2ccccc21 +CCn1ncc(Br)c1C(=O)NC1CCCC(C)C1C +O=C(NCc1ccc(OC(F)F)cc1)NC1CC1 +COC(=O)c1cccc(CCNC(=O)CC2(O)CCCC2)c1 +CCOc1ccc(S(=O)(=O)n2cc(C)nc2CC)c2ccccc12 +COCCN1CCN(C(=O)c2cnc(-c3cccnc3)nc2)CC1 +CCc1n[nH]c(C2CN(Cc3nc(C)c(C)o3)CCO2)n1 +CC(NC(=O)c1cc(CN2CCOCC2)on1)c1ccc(Cl)cc1 +Cc1nn(C(C)(C)C)c2nc(C3CC3)cc(C(N)=O)c12 +Cc1ccc(CCNC(=O)Nc2ccnc(C(=O)N(C)C)c2)c(C)c1 +CCOC(=O)C1Oc2c(c(=O)oc3ccccc23)C1c1cnn(C)c1 +Cc1ccc(Br)cc1S(=O)(=O)NCCO +O=c1[nH]c(SCc2ccc(Br)cc2)nc2[nH]ncc12 +O=C1CCc2cc(C(=O)Nc3cccc(-c4ccn[nH]4)c3)ccc2N1 +Cc1cc(C)n(CCCNC(=O)c2cc(-c3ccco3)cs2)n1 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccn(-c2ccc(F)cc2)n1 +CC(=O)N1CCCC2(CCN(C(=O)c3c(C)noc3C)CC2)C1 +CCC1=NC2(CCC3CN(c4ncccn4)CC32)C(=O)N1CC(C)C +CCc1ccc(CC)c(NC(=O)CNC(=O)NC)c1 +O=C(c1cc2ccncc2cn1)N1CCCN(C(=O)C2CCC2)CC1 +Cc1nc(C2CCCN(S(=O)(=O)c3ccccc3C#N)C2)n[nH]1 +COC1CCC(CC(=O)Nc2nonc2C)CC1 +CCNC(=O)c1cccc(NCc2cccnc2)c1 +Cc1cccc(-c2ccc(C(=O)OCCN3CCOC3=O)c(=O)[nH]2)c1 +Cc1cc(NC(=O)C(Cc2ccccc2)NC(=O)C2CC2)no1 +Cc1noc(-c2ccc(C(=O)Nc3ccccc3O)cc2)n1 +N#CCCCOc1cccnc1NC(=O)c1ccc(Cl)cc1 +O=C(NCc1ccc(C(=O)N2CCCC2)cc1)C1CCO1 +CC(Nc1cccc(CO)c1)C(=O)N1CCc2ccccc21 +CCCS(=O)(=O)N1CCC(NC(=O)N2CCC2)CC1 +Cc1ccc2c(c1)CNCC2C(=O)N1CCCCC1 +Cc1cc(C(=O)N2CCCN(S(C)(=O)=O)CC2)no1 +CNc1nc(SCC(=O)OC)nc(N2CCOCC2)n1 +CCCCNC(=O)c1cc2c([nH]c1=O)CC(C)CC2=O +COC(=O)c1cc(-c2ccncc2)nc(N(C)C)n1 +CCS(=O)(=O)N1CCN(Cc2cn(C)nc2-c2ccccc2)CC1 +COc1ccc(C(=O)N2CCC(C(N)=O)CC2)cc1C +NC(=O)C1CCCN(C(=O)c2cccc(OCC(F)F)n2)C1 +CC(C(=O)NCc1ccc(Br)cc1F)n1ccnc1 +CC(C)Oc1ccc(CNC(=O)Cc2ccc[nH]2)cc1 +Cc1cc(C(=O)NCCOCC(F)(F)F)c(C)n1-c1nccs1 +C=CCn1c(SCC(=O)NC2CC2)nnc1-c1ccccc1 +CCCC1CN(C(=O)Cc2csc(-c3cccnc3)n2)CCO1 +COc1ccc(NC(=O)c2ccc(Cn3cncn3)cc2)cc1 +COc1ccc(C(=O)N2CCNC(c3nc4ccccc4[nH]3)C2)cc1 +Cn1nc(C2CCCN(C(=O)C3CCOCC3)C2)c2cccnc21 +Cc1ccc(=NS(=O)(=O)c2ccc(C)c(C)c2)[nH]c1 +CC(C)C(C)NS(=O)(=O)c1cc(N)cc(Cl)c1F +Cn1cc(CNc2cccc(-c3cnco3)c2)cn1 +CCC(NS(=O)(=O)c1cc(C)sc1C)c1cccs1 +O=C1CN(C(=O)CCCC(=O)Nc2nccs2)CCN1 +Cc1cc(S(=O)(=O)NC(C)C)c(C)cc1Cl +Cn1cc(Cl)cc1C(=O)NCCC(=O)NC1CCCC1 +Cc1ccc(NC(=O)Cn2ccccc2=O)cc1C(F)(F)F +CCc1onc(C)c1NC(=O)Cc1n[nH]c2ccccc12 +CNS(=O)(=O)Cc1ccccc1CNS(C)(=O)=O +N#CCC(=O)Nc1ccc(C(=O)OCC(=O)C2=NC=CC2)cc1 +O=S(=O)(c1ccccn1)N1CC(n2cc(-c3ccccc3)nn2)C1 +CC(CC(=O)OC(C)(C)C)NC(=O)Nc1ccccc1 +Cc1ncccc1CNC1(c2ccc(F)cc2F)CCOCC1 +CCOCCCNc1ncnc2onc(-c3ccccc3C)c12 +O=C1CCN(C(=O)c2ccc3ccccc3c2O)CC1 +O=C(c1ccncc1)N1CCC(c2c[nH]c3ccccc23)CC1 +CC(C#N)Sc1nnc(-c2cccs2)n1CC1CCCO1 +CC(NC(=O)NCC(=O)NC1CC1)c1ccc(Cl)cc1 +COc1ccc(CNc2cnn(-c3ncccn3)c2)cc1C#N +CCCC1CN(c2cnccn2)CC1NC(=O)CN1CCCC1=O +CCc1cccc(OCc2nc(C)c(C#N)s2)c1 +CSc1ccccc1C(=O)Nc1ccc(CC#N)cc1 +COc1cc(C(=O)Nc2cc(C)cc(C)c2)cc(OC)c1OC +CC(C)(C)OC(=O)NCCC(=O)NCc1cccc(F)c1 +N#Cc1c(NC(=O)Cn2c(=O)oc3ccccc32)sc2c1CCC2 +O=C(NCc1cccnc1)Nc1ccc(C(=O)NC2CCCC2)cc1 +COCCN1CCN(C(=O)Nc2cc(C#N)ccc2C)CC1=O +Cc1cc(C(=O)Nc2cnc3ccccc3c2)no1 +CCOc1ccccc1NC(=O)N(C)Cc1ccccn1 +O=C(c1nccs1)C1CCN(C(=O)Cc2ccc(Cl)cc2)CC1 +CCOC(CC)C(=O)Nc1ccc(-c2nncn2C)cc1 +Cc1ccc2cccc(OCc3nc(N)nc(N(C)C)n3)c2n1 +CCNC1C(=O)Nc2ccc(Br)cc21 +CCC(C)NC(=O)c1cccc(-c2nc3cccnc3n2C)c1 +COCCNC(=O)CNC(=O)c1cc(-c2csc(C)n2)c[nH]1 +COc1ccccc1-n1c(C)cc2c(cnc3ncnn32)c1=O +Cc1cccc(NC(=O)N(C)C(C)CC#N)c1C(=O)N1CCCC1 +Cc1cc(F)ccc1S(=O)(=O)N(C(C)C)C1CCC1 +N#CCCn1c(SCC(=O)NCc2ccco2)nc2ccccc21 +COc1ccccc1OCC(=O)N1CCc2ccc(N)cc21 +COC(=O)Nc1cccc(NC(=O)Cc2ccc[nH]2)c1 +CC(=O)Nc1nc2c(s1)CN(C(=O)c1cc3ccccc3[nH]1)CC2 +CC(C)c1cc(C(=O)NCc2cscn2)nn1C(C)(C)C +CCn1cc(C(C)=O)c2cc(Br)ccc21 +Cn1ccnc(NC(=O)COc2ccccc2Cl)c1=O +O=C(Cc1ccc(OC(F)(F)F)cc1)NCCCO +Cc1csc(=O)n1CC(=O)NCc1ccccc1Cl +O=C(Cc1coc(-c2ccccc2)n1)N1CCc2ccc(O)cc2C1 +CCCCN(CC(F)(F)F)C(=O)c1ccc(NC(C)=O)cc1 +CC(C)c1ccc(C(=O)NCC2CN3CCCCC3CO2)cc1 +O=C(NCCCc1nc2ccccc2[nH]1)NCC(F)(F)F +Cc1occc1COC(=O)c1ccc(CSc2nccn2C)o1 +O=C(NCC1Cc2ccccc2O1)Nc1nnc(C2CC2)s1 +Nc1cc(F)c(S(=O)(=O)CC2CCCO2)c(F)c1 +NC(=O)CCCNC(=O)c1cc2c(Cl)c(Cl)ccc2[nH]1 +Cc1cccc(-c2[nH]ncc2CNc2cnn(CC(C)C)c2)c1 +COC(=O)c1ccc(CSc2ncnc3[nH]ncc23)cc1 +Cc1cc(C#N)ccc1OCc1cc(=O)n(C)c(=O)n1C +COc1cc(C)sc1C(=O)N1CCN(c2cccc(C)c2)CC1 +COC(=O)N(C)CC(=O)NC(C)(C)c1ccccc1 +CN(CCCOc1ccc(Cl)cc1)C(=O)c1cnns1 +N#Cc1c(-c2cccc(F)c2)nn(-c2ccncn2)c1N +COc1ncccc1CNC(=O)N1CCC(OCC(C)C)CC1 +COc1cccc(C(=O)N(CCO)Cc2ccccc2OC)c1 +CC(C)N(C)C(=O)Cn1nnn(-c2ccccc2)c1=O +COC(=O)c1cc(F)ccc1Cn1cnc2ccccc2c1=O +COC(=O)C1(N(C)C(=O)Cc2ccc(NC(C)=O)cc2)CCCCC1 +CCS(=O)(=O)NC(C)C(=O)Nc1cccc(S(=O)(=O)NC)c1 +COC(=O)c1n[nH]cc1CN(C)Cc1nc(-c2ccccn2)no1 +Cn1cnc(-c2ccc(F)cc2)c1NC(=O)c1nccc2ccccc12 +CC(C)c1cc(-c2nc(-c3ccc(C#N)cn3)no2)nn1C(C)(C)C +O=C1c2cccnc2CN1Cc1csc(Cc2ccccc2)n1 +CCCC1CN(C(=O)Nc2cccc(N3CCCNC3=O)c2)CCO1 +Cc1nnc(NC(=O)CCc2c(F)cccc2F)s1 +CCCCCC(C)(C)CNC(=O)c1cnn(C)c1 +COc1cncc(N2CCN(Cc3cn(C)nc3C(C)(C)C)CC2)n1 +COC(=O)C(NCC(F)(F)F)c1ccc(OC)cc1 +Cc1nn(C)c(C)c1NC(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +CN(C)S(=O)(=O)CCCSc1ccccn1 +C=CCOc1ccc(C(=O)NCC2(C(N)=O)CCOCC2)cc1 +O=C(CN1CCNc2cc(F)ccc21)NCC1CCCO1 +Cc1cccc(OCCNC(=O)C2CC(=O)N(C(C)C)C2)c1 +COC(=O)c1ccc(C(=O)N2CCC(Oc3cnccn3)CC2)cc1 +Cc1ccc(C)c(C(=O)Nn2cnc3ccccc3c2=O)c1 +CC(C)(CO)n1c(-c2ccccc2F)nc2cc(N)ccc21 +COc1ccccc1C(NC(=O)CC1(O)CCCCC1)c1ccco1 +Cc1ccc(-c2nnn(CCCNS(C)(=O)=O)n2)cc1 +CS(=O)(=O)c1ccc(NC(=O)CCc2ccc(Cl)cc2)cn1 +CCC(NC(=O)Cn1ncc(N(C)C)cc1=O)c1ccnn1C +Nc1cc(C(=O)NCc2ccc3c(c2)OCO3)ccc1F +O=C(NCC1CC1)Nc1ccc(S(=O)(=O)CC2CCOC2)cc1 +CCNC(=O)CNC(=O)CCSc1ccccn1 +O=C(NCc1ccc(O)cc1)Nc1ccncc1F +O=C(CN1C(=O)c2ccccc2Oc2ncccc21)NCc1ccco1 +CC(=O)NC(CC(=O)Nc1ccn(C)n1)c1cccs1 +CCCCCN(C(C)=O)C(C)c1nc2ccccc2c(=O)[nH]1 +CN(Cc1cccc(C(N)=O)c1)C(=O)NCC1CCC1 +CCc1ncc(C(=O)N2CCN(CC3CCCO3)CC2)cn1 +CC(=O)Nc1cccc(NCC(=O)NCc2ccccc2)c1 +CCOc1ccc(CC(=O)Nc2cccc(N)c2)cc1 +COc1cc(=O)n(-c2ccccc2C)nc1C(=O)NC(C)C +O=C(NC(CCCO)c1ccccc1)c1ccc2cc[nH]c2c1 +CC(=O)OCC1CC(=O)N(C)C1c1cccc(Cl)c1 +O=C1CC(C(=O)Nc2cccc(F)c2)c2ccc(F)cc2N1 +COC(=O)c1cccc(C(=O)Nc2ccccc2OC)c1 +N#Cc1ccccc1N1CCCN(S(N)(=O)=O)CC1 +CC(C)C(=O)Nc1cccc(C(=O)NC2CCCC2)c1 +COc1ccc(-c2nc(C(=O)NCCN3CCOCC3)cs2)cc1 +CCOCCC(=O)Nc1nc2ccc(F)cn2n1 +Cc1ccc(NC(=O)N2CCN(Cc3ccccn3)CC2)c(C)c1 +O=C1CCC2(CCN(C(=O)c3ccc(=O)[nH]c3)CC2)CN1CC1CC1 +COc1cccc(-c2nnc(Cc3nc(-c4cccs4)no3)o2)c1 +COc1ccc(C)cc1NC(=O)c1cccnc1OCC(F)F +Cc1cc(C)n(Cc2ccc(C(=O)N(C)C3(C#N)CCC3)cc2)n1 +O=C(CNC(=O)c1cccc(Br)c1)NCCCO +COc1ccccc1Oc1cc(N2CCC(C)CC2)ncn1 +COCCNC(=O)Cn1nc2c(C)cc3cc(C)cc(C)c3n2c1=O +COc1ccc(-c2cc(C#N)c3c(c2)CCN3)cc1 +CC1CC(C)CN(C(=O)c2cccc(Oc3ccccn3)c2)C1 +Cn1cnnc1-c1ccc(NC(=O)c2ccc(C#N)cc2)cc1 +COc1ccccc1CNC(=O)CN1CCN(C(C)=O)CC1 +O=C(CN1CCCCC1=O)NCc1ccc(OC2CCCC2)nc1 +CCc1nn(C)c(OC)c1CN(C)Cc1nc(-c2cccnc2)no1 +Cc1csc(-c2ccc(NC(=O)N3CCCC3)cc2)n1 +CN(C)C(=O)CC1C(=O)NCCN1Cc1ccc(F)c(F)c1 +CC(NC(=O)CSc1nnnn1C)c1ccc2c(c1)OCCO2 +CN(C)C(=O)c1c[nH]nc1-c1ccc(CNC(=O)c2ccccc2)cc1 +N#Cc1ccccc1OCC(=O)N1CCOc2ccccc21 +O=C(CC1NC(=O)c2ccccc21)NCCSc1ccccn1 +Cc1cccnc1CN(C)C(=O)c1cccc(CCC(C)(C)O)c1 +CC(=O)NC(CC(=O)NCc1ccccc1CO)c1ccccc1 +CSc1nsc(SCC(=O)c2ccc(NC(C)=O)cc2)n1 +O=C(Nc1ccccn1)c1ccc(S(=O)(=O)c2ccccc2)s1 +CC(=O)Nc1ccc(NC(=O)Cn2cnnn2)cc1Cl +CCc1noc(CC)c1CNC(=O)c1n[nH]c2ccc(C)cc12 +CC(COc1ccccc1)OC(=O)c1ccc(S(C)(=O)=O)cc1 +COCC(C)NC(=O)CSc1c(C)c(C)cc(C)c1C +CC(C)n1nnnc1-c1ccc(NC(=O)N(C)CC2CC2)cc1F +Cc1ccc(N(C)S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)cc1 +C=CCNC(=O)CNc1cccc(C(=O)NCC)c1 +COC(=O)c1ccccc1NC(=O)Cn1nccc1-c1ccncc1 +CCc1noc(CC)c1CC(=O)NCc1nc(C(F)(F)F)cs1 +COc1cccc(OC)c1C(=O)Nc1nccs1 +Cc1ccccc1Cn1c(-c2ccncc2)n[nH]c1=O +CC(C)(C)NC(=O)CSc1nnc(-c2cccs2)n1C1CC1 +COc1ccc(S(=O)(=O)NCc2cccnc2)cc1C(N)=O +COCc1nn(Cc2cccc(NC(=O)OC(C)(C)C)c2)c(=O)o1 +Cc1cccc(NC(=O)c2cccc(CN3CCCC3=O)c2)n1 +CCNC(=O)CN(CC)S(=O)(=O)c1ccc(OC)cc1C +CCc1ccc(S(=O)(=O)N2CCOc3ncc(C)cc32)cc1 +Cc1ccccc1C(=O)N1CCC2(CC1)OCCCO2 +COc1cc(NC(=O)Cc2ccccc2C)cc(OC)c1 +CC(NC(=O)CN1CCOCC1C1CC1)c1ccccc1Cl +Cc1nnc(COc2ccc(Oc3ccccc3)cc2)o1 +COC(=O)c1ccc(S(=O)(=O)N2CC(C)c3ccccc32)o1 +CN1CC(=O)N(CC(=O)N2CCCCC2)c2ccccc2C1=O +O=S(=O)(NCCc1c(F)cccc1F)N1CCCCCC1 +COc1cc(C)sc1C(=O)N(C)Cc1cccc2ncccc12 +CC(C)N(CC(F)(F)F)C(=O)c1ccc(C(=O)c2cc[nH]c2)cc1 +Nc1ccnc(C(=O)Nc2cccc(C(F)(F)F)c2)c1 +Fc1cc(Br)cc2c1CCNC2c1cc[nH]n1 +Cc1ccsc1CN(C)C(=O)c1ccc(-c2nc[nH]n2)cc1 +COc1ccc(CC2CCN(C(=O)Nc3cc(C)on3)CC2)cc1 +COc1ccc(CNc2ncnc(N)n2)cc1Cl +CCn1nc(-c2ccccc2OC)cc(CO)c1=O +O=C(NCc1ccccc1)c1nc2ccccc2[nH]1 +Cc1csc(C(NCC(O)c2ccc(F)cc2)C2CC2)n1 +NC(=O)Cn1c(=O)ccc2cccc(OCc3ccc(F)cc3)c21 +O=C(c1ccc[nH]1)N1CC2CCN(c3ncccn3)CC2C1 +CCN1C(=O)c2oc3cc(C)c(C)cc3c(=O)c2C1c1ccccn1 +COCCC1COC2(CCN(C(=O)C3CCC3)CC2)C1 +O=C(c1ccncc1)N1CCC(c2nc(C3CC3)no2)C1 +CCNC(=O)c1ccc(NC(=O)c2ccc(OC)cc2O)c(C)c1 +CCN1CC2(CC1=O)CN(C(=O)C(C)C)CCN(C(=O)N(C)C)C2 +Cc1ccc(-c2c(C)sc3nc(C)nc(N(C)CCO)c23)cc1 +CC(c1ccccc1Cl)N(C)C(=O)c1ccc(C(N)=O)cc1 +COc1ccc(C(=O)Nc2nc(-c3ccc(C)cc3C)cs2)nn1 +COc1cc(CN(CCC#N)CC2CC2)cc(Br)c1O +CCC(C)CN(C)C(=O)c1cc(Br)ccc1F +Cn1nccc1CNC(=O)Nc1cccc(C(F)(F)F)c1 +OCC1OC(n2ccc3ccccc32)C(O)C(O)C1O +CCCNC(=O)C(C)NC(=O)c1cc(N)cn1C +CCc1cn[nH]c1C1CCCN(C(=O)c2cnc(NC(C)C)nc2)C1 +O=C(Nc1cc(F)cc(N2CCCC2)c1)c1cn2cccnc2n1 +CCOc1ccccc1CN1C(=O)c2ccccc2S1(=O)=O +CCc1sc(C(=O)N2CCCC(c3nc(C)no3)C2)cc1C +CCCOc1ccc(CNC(=O)NC(C)c2nc(C)cs2)cn1 +CCOc1ccccc1NS(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +CC(C)N(C)S(=O)(=O)N(C)Cc1cccc(C#N)c1 +NC(=O)Cc1ccccc1NCc1csc2ccccc12 +CCOc1ccc(S(=O)(=O)N(C)Cc2ccc(F)cc2F)cc1 +CC(NC(=O)C(C)(C)C)C(=O)OCc1cccc(F)c1 +O=C(NC1CCCC1)C1CCCN1C(=O)Nc1ccccc1Cl +Nc1cc(NC(=O)Cc2ccccc2F)ccc1F +NS(=O)(=O)c1ccc(NC(=O)c2cccnc2)cc1 +CCOCC1CCCN(C(=O)Nc2ccc(F)cc2)C1 +CN(Cc1ccc(F)cc1F)S(=O)(=O)c1cccc(C#N)c1 +Cc1ccc2c(c1)N(CC(=O)N1C(C)CCCC1C)C(=O)CO2 +CCCn1nc(C(=O)NC(C)Cc2ccccc2F)ccc1=O +C=CCOC1C2CCC1N(Cc1scnc1C)CCO2 +O=C(Cc1ccc[nH]1)NCC(=O)N1CCC(Cc2ccccc2)CC1 +CCN(CC)C(=O)CNc1ccccc1C(=O)N1CCCC1CO +Cc1ncc(CN2CCCC(c3cncc(-n4ccnc4C)n3)C2)cn1 +O=C(NCc1ccccn1)c1cc(F)ccc1Br +Cc1ccsc1CNC(=O)NCCC1CCCC1 +COc1ccc(-c2noc(CN(C)Cc3cccs3)n2)cc1OC +Cc1cc2c(cc1C)N(CC(=O)Nc1ccccn1)CCN2 +N#CCCn1ncc2c(N3CCN(S(N)(=O)=O)CC3)ncnc21 +NC(=O)CCSc1nnc(Cc2ccccc2)o1 +Cc1ccnc(NC(=O)C(C)Oc2ccccc2)n1 +O=C(C1CC1c1cccnc1)N1CCCN(c2cccnn2)CC1 +Cc1ccc(N(CCC#N)C(=O)C(C)Sc2nnc(C)n2N)cc1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1cccc(OC(F)F)c1 +COc1cccc(CC(=O)Nc2cnc(C(C)(C)C)nc2)c1 +CCCC1CCC(NC(=O)CCn2ncc(=O)c3ccccc32)CC1 +O=C(Nc1ccccc1C(=O)N1CCCC1)c1ccccc1 +Cn1ccc(C(=O)NCC(c2cccs2)N2CCCC2)cc1=O +COc1cccc(-c2noc3c2CN(c2ncccn2)CC3)c1 +O=C1CN(Cc2cn(-c3ccccc3)nc2-c2ccccc2)CCN1 +Cc1cc(C)c(C(=O)Nc2ccc(CN3CCOCC3)cc2)o1 +CN(C)C(=O)COC(=O)Cn1cnc2ccccc21 +Cc1cc(Cl)ccc1OCC(=O)Nc1ccccc1CO +CCC(C)NS(=O)(=O)c1cc(-c2ccc(=O)[nH]n2)cs1 +Cn1nccc1CNC(=O)N1CCN(Cc2ccccn2)CC1 +O=C(Nc1cccc(C(=O)N2CCOCC2C2CC2)c1)NC1CC1 +CCOCCCNS(=O)(=O)c1cccc2cnccc12 +CC(C)OC(=O)c1ccc(Cn2c(CO)nc3ccccc32)cc1 +Cn1nc(C(=O)Nc2cccc(C(=O)NC(C)(C)C)c2)ccc1=O +COc1ccc(Cl)cc1-c1nn2c(C3CC3)nnc2s1 +Cn1c(SCc2cccc(OCC(N)=O)c2)n[nH]c1=O +CCn1ncc(Br)c1C(=O)Nc1ccn(CC#N)n1 +Cc1cc2c(=O)n(CC(=O)NCc3ccc(Cl)cc3)cnc2s1 +COc1ccc(Cc2ncc(CO)s2)cc1OC +Cc1ccc(-c2ocnc2C(=O)NCc2n[nH]c(=O)[nH]2)cc1 +COCc1cccc(C(=O)N2CCN(c3ccccc3)CC2)c1 +CCOC(=O)CCCSc1nc2ccccc2[nH]1 +CC(C)CNC(=O)CN1C(=O)c2cccc3cccc1c23 +Cc1cc(C(=O)NCC2(N3CCOCC3)CCCCC2)c(C)o1 +O=C(CCCNc1ncccn1)N1CCc2ccccc2C1 +COCc1cccc(NC(=O)c2csnc2C)c1 +CCn1cc(S(=O)(=O)c2ccc(C)cc2)[nH]c1=O +COC(=O)c1ccc(S(=O)(=O)N2CCN(CC(F)F)CC2)o1 +CCN1CCN(C(=O)C(C)Sc2ccccc2C#N)CC1 +CCOC(=O)c1ccc(NC(=O)c2cnn(C(C)(C)C)c2)cc1 +CC(NC(=O)c1c[nH]c(=O)c2ccccc12)c1nc2ccccc2[nH]1 +CN(C1CCCCC1)S(=O)(=O)c1ccc(SCCO)nc1 +Cn1c(=O)nc2n(-c3ccccc3)c3cc(Cl)ccc3cc-2c1=O +Cc1nc(C)c(C#N)c(SCC(=O)N2C(C)CCCC2C)n1 +O=c1c2ccccc2nnn1CC(O)COCc1ccco1 +CCC(Oc1ccccc1F)C(=O)Nc1cc(C)on1 +Cc1nc(C)c(C(C)NC(=O)c2cscn2)s1 +CCC1CCC(NC(=O)Cc2c(C)noc2C)CC1 +COc1ccccc1C(=O)Nc1c(C(N)=O)cnn1-c1ccccc1 +Cn1ccnc1SCC(=O)NCCc1ccco1 +CS(=O)(=O)NC1CCCN(C(=O)c2cc(=O)[nH]c3ccccc23)C1 +C#CCN1CCN(CC(=O)NCc2ccc(C)cc2)CC1 +Nc1ccc(F)c2ccnc(C(=O)Nc3ccc(F)cc3F)c12 +CCn1nc(-c2cc(Cl)c(C)cc2OC)cc(C#N)c1=O +COc1cccc(-c2c3cnn(C(C)C)c3nc3[nH]c(=O)sc23)c1 +O=C(Nc1ccc(N2CCCC2)nc1)c1c(F)cccc1Cl +O=C(Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1)C1CC=CC1 +Cc1c(C(=O)N(CC(=O)Nc2ccc(F)cc2)C(C)C)cnn1C +CCCNC(=O)C(C)NC(=O)c1cc(Br)ccc1Cl +C#Cc1cccc(NC(=O)CNC(=O)NC(C2CC2)C2CC2)c1 +CS(=O)(=O)N1CCC2(CC1)CN(CC1CC1)C(=O)CO2 +COCC(=O)N1CCN(c2ccccc2F)CC1 +Cc1ccc2c(c1)cc1c(=O)n(CC(=O)N3CCOCC3)nc(C)n12 +CNC(=O)CN1CCOC2CN(Cc3ccc(C)s3)CC21 +COC(=O)c1cc(-c2csc(NC(=O)c3ccc[nH]3)n2)c[nH]1 +NC(=O)Nc1ccc(CNC(=O)c2ccc3cc[nH]c3c2)cc1 +CC(C)Sc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 +CC(=O)NCCC(=O)Nc1ccc(N2CCCS2(=O)=O)cc1 +CCC(NC(=O)C1CCN(C)C(=O)C1)c1ccccc1OC +COc1ccc(S(N)(=O)=O)cc1C(=O)NC(C)c1ccncc1 +CC(=O)c1cc(CC(=O)NCc2cnc(C)cn2)cs1 +Cn1cc(C(CO)NC(=O)NCC2(c3cccs3)CCCC2)cn1 +CC(=O)NC(CC(=O)N1CCCC(c2ccn[nH]2)C1)c1ccccc1 +CN(Cc1ccc(F)cc1)C(=O)CNc1ccc(F)cc1Cl +N#Cc1ccc(N2CCCC(n3cc(C(=O)NCCO)nn3)C2)nc1 +CN(Cc1cccc(C#N)c1)C(=O)c1ccncc1 +COCc1cccc(C(=O)N2CCCC(NS(C)(=O)=O)C2)c1 +Cc1c(N)cccc1C(=O)N1CCCC1CCCO +CCn1nnnc1-c1cccc(C(=O)Nc2ccon2)c1 +CNC(=O)c1ccc(NC(=O)CCC(=O)c2ccc(C)s2)cc1 +Cc1ccc(-n2nc(C)c(C(=O)Nc3nnc4ccccn34)n2)c(C)c1 +Cc1nc(CN(C)Cc2c(F)ccc(F)c2Cl)no1 +O=C(CSc1nnnn1-c1ccccc1)c1ccc(F)cc1 +COc1ccc2cc(NC(=O)c3cc(C)n(C)n3)cnc2c1 +O=C(C1CC2CCC1O2)N1CCCCc2ccccc21 +COCC(=O)Nc1cccc(NC(=O)NC(C)C)c1 +Cc1sc(=O)n(Cc2ncc(C(C)(C)C)o2)c1C +Cc1cccc(Nc2ccccc2C(=O)N(CC(N)=O)C(C)C)c1C +COc1cc(CC(=O)N2CCCC(C)CC2)cc(OC)c1OC +COc1cccc(-c2noc(-c3c[nH]c4ccccc4c3=O)n2)c1OC +CN1C(=O)C(C)(C)COc2ccc(C(F)(F)F)cc21 +CC(NC(=O)C1CC(=O)OC12CCCCC2)c1ccncc1 +CCc1cc(N2CCN(C(C)=O)CC2)n2nc(C)c(C)c2n1 +O=C(c1ccc(Cl)cc1)N1CCN(c2ccccc2)CC1 +CC(Cc1nnc(SCc2nnnn2C2CC2)o1)c1ccccc1 +COCC(O)CN(C)S(=O)(=O)C1CCCCC1 +CCn1ccnc1-c1nccn1-c1ccccc1CN1CCOCC1 +CN(C)C(=O)Cc1ccc(NC(=O)c2nc3ccccc3s2)cc1 +COc1ccc2[nH]cc(C(=O)CN3CCc4ccccc4C3)c2c1 +CCN(C)C(=O)c1ncn2c1CN(CC)S(=O)(=O)c1ccccc1-2 +O=c1cc(CSc2ccccc2O)nc2ccccn12 +Cc1c(C)n(C(=O)Cn2nnc3ccccc3c2=O)c2ccccc12 +CCc1cc(Nc2cnn(CCO)c2)n2ncnc2n1 +Cc1c(CO)cnn1-c1cccc(Cl)c1Cl +COCc1cn(C2CCN(C(=O)c3cc[nH]n3)CC2)nn1 +O=C(Nc1ccc(C(=O)NCC(=O)N2CCCC2)cc1)NC1CC1 +Cn1cc(C(=O)N2CCCCc3ccccc32)ccc1=O +Cc1sc(CNC(=O)c2nccnc2N)nc1-c1ccccc1 +CC(=O)c1nnn(CCCOc2ccc(Cl)cc2)c1C +O=C(COc1cccc2c1CCC2=O)Nc1cc(F)ccc1F +Cn1c(COc2ccc(C(=O)NC3CC3)cc2)cc(=O)n(C)c1=O +O=C(Nc1ccnc2ccc(F)cc12)c1cccc(F)c1 +CCC(=O)Nc1cccc(NC(=O)c2ccc(OC)cc2OC)c1 +Cc1nnc(N2CCCC2c2ccc(F)cc2)s1 +CCC(C)(C#N)NC(=O)c1sccc1Br +O=c1[nH]c2cccc(F)c2n1Cc1ccccc1F +O=C(OCCNc1cccnn1)c1ccc(-n2ccnn2)cc1 +CC(C)NC(=O)C1CCCN1C(=O)c1cccc2nscc12 +CCn1cc(Cl)c(C(=O)Nc2c(C(=O)OC)nn(C)c2C)n1 +CNC(=O)CNC(=O)NCc1cc2c(s1)CCC(C)(C)C2 +N#CCCN(Cc1ccco1)C(=O)c1cnc(C2CCCO2)s1 +COc1cccc(CN2CCCC(c3cc(C(N)=O)n[nH]3)C2)c1 +COc1ccc(N)c2c(C(=O)NCC(C)O)nccc12 +O=C(CSc1ccc(F)cc1)Nc1cccc(-n2cnnc2)c1 +CCN(CC(C)C#N)S(=O)(=O)c1ccccc1F +COc1ccc(C(=O)NCc2ccccn2)c(O)c1 +CCc1cccc(C)c1NC(=O)c1cc2ccccc2oc1=O +Oc1ccc(CN(CC2CC2)c2cc(-n3ccnc3)ncn2)cc1 +CC(NCC(=O)N1CCNC(=O)C1)c1ccc(Cl)cc1Cl +O=C(c1ccc(=O)[nH]c1)N1CC(c2nc(-c3ccccn3)no2)C1 +CN(CC(=O)NC(C)(C)C)c1cc(N2CCCC2CO)ncn1 +CCN(CC(C)C#N)C(=O)Cc1cccc(Cl)c1 +CCOCC(=O)NC(c1ccccc1)c1ccncc1 +Cc1ncc(CN(C)C(=O)c2ccc(=O)[nH]c2)s1 +C=CCOC(=O)c1sc(-c2nc[nH]n2)nc1C +CCOC(=O)c1sc(NC(=O)C2CCCC2)c(C(N)=O)c1C +Nc1ccc(-n2cnc(=O)c3ccccc32)cc1Cl +Cc1cccc(NC(=O)N2CCOCC2C2CC2)c1 +CS(=O)(=O)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1 +CC(C)(C)CC(=O)NCC(=O)NC1CCCCNC1=O +Cc1cccc(CN(C(=O)c2ccc(N3CCCC3=O)cc2)C2CC2)c1 +CCOCCn1c(=O)[nH]c2cc(C(=O)N3CCCC3)ccc21 +CC(C)c1cc(CNC(=O)NCC(C)(C)c2ccncc2)on1 +O=C(CC1C=CCC1)NCc1cccnc1-n1cccn1 +CCOC(=O)CN(CC)C(=O)c1cccc(C(F)(F)F)c1 +Cc1cc(NC(=O)NC(C)c2ccncc2)ccc1F +Cc1n[nH]cc1NC(=O)c1ccc(F)cc1Br +CCN(C(=O)c1cn[nH]c1)C(C)c1cccc(O)c1 +O=C(Nc1cccs1)N1CC(c2nc(C3CC3)no2)C1 +CCc1onc(C)c1NC(=O)C(C)(C)c1cccs1 +CCOC(=O)c1cnn(-c2nc(C)nc3sccc23)c1N +CCOc1ccc(NC(=O)c2cnc(C3CCCO3)s2)c(C)c1 +CCc1noc(CC)c1CC(=O)NCCc1c[nH]c2cc(F)ccc12 +CN(C)C(=O)COC1CC2CN(Cc3ccccn3)CCN2C1 +CCCN1C(=O)c2[nH]nc(-c3ccccc3)c2C1c1ccc(O)cc1 +COC(=O)c1ccccc1NC(=O)CCC(N)=O +CCOCCCNC(=O)N1CCc2ccc(OC)cc2C1 +O=C(NCCOCc1ccc(Cl)cc1)c1scnc1C1CC1 +CN1CC2(CCN(Cc3ccnc4ccccc34)C2)OC1=O +CC(CO)NC(=O)c1ccc(Oc2ccccc2)nc1 +CC(OC(=O)c1ccc(F)cc1N)C(=O)Nc1ncnc2nc[nH]c12 +Cc1cccc(O)c1NCc1cccc2cc[nH]c12 +COC(=O)c1cc(CSc2nnc(C)s2)oc1C +CCN1CCN(C(=O)CCC(=O)Nc2nnc(C)s2)CC1 +COCc1ccc(C(=O)Nc2cccc(-c3nc(C)c(C)o3)c2)o1 +COC(=O)CNC(=O)C1(n2cnnn2)CCCCC1 +CCOc1cc(C(=O)NCCN2CCOCC2)ccc1OC +C=CCNc1nnc(SCC(=O)N(C)C2CCCCC2)s1 +CCOc1ncccc1CNC(=O)c1cc(-c2csc(C)n2)c[nH]1 +CC12CC3(C)CC(C)(C1)CC(C(=O)NC(C)(C)CO)(C2)C3 +C=CCOCC1CCC2C1OCCN2S(=O)(=O)c1cn(C)cn1 +COCCCn1ccc(NCc2ccccc2Cl)n1 +O=C(NCc1csc(=O)[nH]1)C1C2CCCCC21 +COc1ccc(NC(=O)Nc2cccc(Cl)c2)cc1OC +CC1C(=O)OC(c2ccccc2F)C(C)(C)C1=O +O=C(Nc1ccc(NC(=O)c2cccs2)cc1O)c1ccco1 +COC(=O)CCNC(=O)CCc1ccccc1Br +Cc1ccc(NCc2nnc(-c3ccccc3)o2)c(C)c1 +COCCN(Cc1ccco1)C(=O)Nc1ccc(C(F)(F)F)cc1 +COc1ccc(F)cc1NC(=O)NCC(=O)NC1CCCCC1 +C#CCN1CCN(C(=O)NCCCCN2CCOCC2)CC1 +Cc1cc(CNC(=O)N2CCN(c3ccccc3)CC2)no1 +CCc1nsc(N2CCN(S(=O)(=O)c3ccccc3)CC2)n1 +Cc1nn(C)cc1NC(=O)C(C)n1nc(C(F)(F)F)c(Cl)c1C +Cc1ccccc1C(C)NC(C)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +N#Cc1ccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3)cc1 +N#CC(C(=O)CCc1ccsc1)c1ccc(C(F)(F)F)cn1 +O=C(N1CCC2(CCOC2)C1)C1(c2ccc(F)cc2F)CCCC1 +Cc1ccc(C(N)=O)cc1NC(=O)C(c1ccccc1)n1cccn1 +COc1ccc2cc(C(=O)N3CCCC3)ccc2c1 +O=C(Nc1cccc(F)c1)c1n[nH]c2c1COc1ccccc1-2 +CCOCCCNC(=O)N1CCC(C(=O)N2CCCCCC2)CC1 +Cc1csc(C(C#N)C(=O)CCc2ccc3c(c2)OCCCO3)n1 +CCCc1c(C)nc2ncnn2c1NCc1ccc(F)cc1 +COc1cc(C(=O)NCc2ccc(F)cc2)cc(OC)c1C +O=S(=O)(NCC#Cc1ccc(F)cc1)c1c(F)cccc1F +COCCc1nc(CNC(=O)Nc2ccc(C(C)C)cc2)no1 +Cc1cccc(CN2C(=O)CNc3ccccc32)c1 +CC(C)N(C)S(=O)(=O)NCc1ccc(S(C)(=O)=O)cc1 +CC(C)N(C(=O)CNC(=O)OCc1ccccc1)c1ccccc1 +Fc1ccc(C2(NCc3cnc4cnccn34)CCOCC2)c(F)c1 +CC(C(=O)Nc1ccc(F)cc1F)n1cnc2ccccc2c1=O +Cn1ccc2cc(C(=O)Nc3ccc4c(c3)OCCCO4)ccc21 +COc1cc(NC(=O)N(C)Cc2ccccn2)c(OC)cc1Cl +COCc1nc2cc(NC(=O)CCc3ccccc3OC)ccc2[nH]1 +O=C(NCCn1ccc(C(F)(F)F)n1)c1ccc2c(c1)OCO2 +Cc1ccc(C(=O)NCC(=O)NCC2CC2C)cc1C +O=c1[nH]c(Nc2cc(Cl)ccc2F)nc2c1CCC2 +COCC(=O)N1CCCN(C(=O)C(c2ccc(C)cc2)N(C)C)CC1 +Cc1ccc(NCc2noc(-c3ccoc3)n2)cc1C +Cc1cccc(-n2nnc(C#N)c2-c2cccnc2)c1 +COc1cc(NC(=O)c2cc3cccc(OC)c3o2)ncn1 +Cc1ccc(-c2nonc2NC(=O)c2ccncc2)cc1 +CC(C)(C)CC1CCCN1C(=O)CCc1nc2ccccc2c(=O)[nH]1 +Cc1ccc(C(O)CNC(=O)c2ccccc2C)o1 +Oc1cc(F)c2c(c1)C(c1ccncc1Cl)NCC2 +CCN1CCN(C(=O)c2nccc3c(N)ccc(F)c23)CC1 +O=C(NC(C1CC1)C1CC1)c1cc2c(F)cccc2[nH]1 +Cc1nc(C2CCCN2C(=O)c2ccc(F)c(COC(C)C)c2)no1 +COc1ccc(Br)cc1CNCC(O)c1ccccc1 +CC(=O)N1CCCc2ccc(C(=O)C3CCCCN3)cc21 +Cc1ccc(C(=O)NC2COc3c2ccc(Cl)c3Cl)c(=O)[nH]1 +N#Cc1nc2ccccc2nc1-c1ccc2[nH]c(=O)oc2c1 +CCOC(=O)c1cc(NC(=O)NCCN2CCOCC2)cn1C +O=C(Nc1ccc2c(c1)C(=O)OC2)Nc1ccccc1Cl +O=C(NC1(c2cccc(F)c2)CCOCC1)C1CCC1 +O=C(Nc1nc(-c2ccccc2F)cs1)C1CC=CC1 +NC(=O)c1ccc(NC2CCCc3ccccc32)cc1 +CC(O)CN(c1ccccc1)S(=O)(=O)c1ccccc1 +Nc1c(F)cccc1C(=O)Nc1ccccc1C(F)(F)F +COc1cc(OC)cc(C(=O)Nc2ccccc2C(C)=O)c1 +O=C(c1cc[nH]c(=O)c1)N1CCC(Oc2cccc(Cl)c2)C1 +Cc1ncncc1-c1ncnn1Cc1ccc(F)cc1 +COc1ccc2[nH]c3c(c2c1)CCNC31CCOCC1 +c1coc(-c2nc3c4c5c(sc4ncn3n2)CCCC5)c1 +Cc1csc(SCC(=O)Nc2nccs2)n1 +COc1cccc(-c2nnc(SCCc3ccccn3)n2C)c1 +CC(NC(=O)c1ccco1)C(=O)NC(C)c1ccncc1 +COC(=O)COc1ccc(=O)n(-c2ccccc2)n1 +CCc1nn2c(=O)cc(CSc3nc(C)cc(=O)[nH]3)nc2s1 +Cc1cc(C(=O)N2CCCC(C)C2)c(C)n1Cc1ccco1 +COC1CCN(C(=O)C2Cc3ccccc3O2)CC1 +Cc1cc2nc(C(C)NC(=O)OC(C)(C)C)cc(O)n2n1 +CC(=O)c1ccccc1NC(=O)Cc1c[nH]c2ccccc12 +CCCNC(=O)CSc1ncnc2c1nnn2CC +Cc1cc(C(=O)Nc2ccc(Cl)cc2)c2c(=O)[nH]n(C)c2n1 +OCCC1CCCCN1c1ncnc2c1cnn2-c1ccccc1 +CCCNC(=O)c1cc(C(C)C)nc(N2CCOCC2)n1 +Cc1nc(-c2ccsc2)sc1C(=O)NCCCC(N)=O +O=C(CC1CCCC1)N1CCN(c2ccccc2F)CC1 +CNc1nccnc1C1CCCN1S(=O)(=O)c1cn(C)cn1 +O=C(NCC(c1ccccc1)N1CCOCC1)c1cccc(F)c1F +COc1ccc(CN2CCOC3(CCCC3)C2)c(OC)c1OC +CCc1cc(NC(=O)C2CCCC(C(F)(F)F)C2)nc(C)n1 +COc1cccc(C(=O)Nc2cc(F)c(F)cc2NC(C)=O)c1F +CC(C)(C)c1ccc(CNc2cccnc2-n2cncn2)s1 +CCCC(C)(CNC(=O)c1ccccn1)NC(=O)c1ccccn1 +Cc1n[nH]c(C2CN(C(=O)c3cc(C)n(CC4CC4)c3C)CCO2)n1 +Cc1ccc(C(=O)NCCNc2cccc(F)n2)cc1 +Cc1cccc(OCC(=O)Nc2nnc(C3CCCO3)s2)c1 +O=C(Nc1cccc2cnccc12)c1cc(F)ccc1F +COC(=O)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1Cl +COCCNC(=O)CNc1cc(Cl)c(Cl)cc1Cl +COc1ccccc1C1CC(=O)c2cn3nccc3nc2C1 +CNC(=O)c1cccc(CCC(=O)N2CCCCC2CCO)c1 +CCOc1ccccc1NC(=O)c1cc2ccccc2oc1=O +Cc1[nH]c2ccccc2c1C(=O)OCC1CCCN1C(N)=O +O=C(Cn1nc(-c2ccc(F)cc2)oc1=O)Nc1ccc(F)cc1F +CNC(=O)c1cc(NC(=O)C(C)Oc2cccc(C)c2)ccc1F +Cc1ccc(C(=O)N2CCC(C(O)c3ccccc3)CC2)c(C)n1 +COC(=O)C1CCCCN1Cc1scnc1C +Cc1cc(NC(=O)N(C)C(C)CC#N)n(Cc2ccccc2)n1 +O=C(c1ccccc1Cl)N1CCCN(C(=O)C2CC=CCC2)CC1 +CCOCc1ccc(CNC(=O)N2CCC(CC(N)=O)CC2)cc1 +NC(=O)C1CCCN(C(=O)c2ccc(F)c(C(F)(F)F)c2)C1 +Cc1ccccc1-c1nc2cnccn2c1NCCC(=O)NC(C)C +CCC(C)C(=O)NCC(C)c1nc(-c2ccccc2)no1 +COCCCC1CCCCN1C(=O)c1cccc(N(C)C)c1 +Cc1noc(C)c1C(=O)N1CCCC1Cn1cccn1 +CCn1ncc(S(=O)(=O)N(C)Cc2c(Cl)cnn2CC)c1C +CC(=O)c1c(N)nc(C)nc1C(Cl)(Cl)Cl +CCNc1oc(COc2ccc(Br)cc2)nc1C#N +CC(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +Cc1ccccc1OCCNC(=O)N1CCN(c2ncccn2)CC1 +O=S(=O)(NCc1cccc(F)c1)c1cn[nH]c1 +O=C(CCNC(=O)c1ccsc1)Nc1cccnc1 +CCc1cc(C(=O)N2CCC3(CCCCC3)C2)[nH]n1 +CCOC(=O)C1=C(C)C(C(=O)NCc2ccc(Cl)cc2)C(C)=N1 +CC(C)Sc1ccc(C(=O)Nc2nnc(-c3ccno3)o2)cc1 +CC=CCOC(=O)CCS(=O)(=O)c1ccc(C)cc1 +Cc1nc(NC(=O)c2csc(NCc3ccco3)n2)sc1C +CC(=O)NCc1ccc(-c2csc(C(C)Cn3cncn3)n2)o1 +O=C(c1ccc2oc3ccccc3c2c1)N1CCCCC1 +Cc1cc(C)cc(NC(=O)N(C)Cc2cnn(C)c2)c1 +CC(C(=O)N(C)Cc1ccccc1N1CCCC1)n1cncn1 +CC(C)CN(CC(C)C)C(=O)c1cccc(F)c1N +O=C(c1ccccc1F)N1CCN(Cc2ccccc2Cl)CC1 +CCOc1ccc(-n2nc3cc(C)c(NC(=O)CC)cc3n2)cc1 +COC(=O)N1CCCc2cc(S(=O)(=O)N3CCOCC3)ccc21 +Nc1ccc(-c2cn(C3OC(CO)C(O)C3O)c(=O)nc2N)cc1 +CN(CC1COc2ccccc2O1)C(=O)CCSc1nnnn1C +CCN(CC1COc2ccccc2O1)C(=O)Cc1cccc(F)c1 +CC(=O)c1csc(NC(=O)c2cccc(-c3ccoc3)c2)n1 +Cc1ccc(-c2ccc(=O)n(CC(=O)NC3CCCC3)n2)cc1C +COc1ccc(Br)c(CNC(=O)c2ccc(C)o2)c1 +COc1c(F)cccc1CNc1ccc(F)cn1 +Cc1ccc(-c2nnc(SCC(=O)NC(C)(C#N)C(C)C)o2)cc1 +Cc1nc(C)c(C(=O)N(Cc2cnc3ccccn23)C2CC2)s1 +COCCN1CCCC2(CCN(C(=O)c3ccc[nH]3)C2)C1=O +CCCc1nnc(N2CCC(OCc3ccccc3)CC2)o1 +COc1ccc(F)cc1S(=O)(=O)N(C)CC(=O)N1CCCCC1 +COc1cc(OC)cc(-c2cc(O)cc(C#N)c2)c1 +Cc1ncoc1C(=O)N1CCOCC1c1nccc(NC2CCC2)n1 +COc1ccc(OC)c(NC(C)c2cccc(O)c2)c1 +O=C(N1CCCCC1)N1CCN(Cc2nnnn2C2CC2)CC1 +Nc1c(NCCN2CCOCC2)ncnc1OC1CCCCC1 +CCC(NC(=O)c1ccc(NC(C)=O)cc1)c1noc(C)n1 +COc1ccc(CN2CCOCC2C2CC2)cc1F +Cc1cc(SCCC(=O)Nc2cccc(Cl)c2C)ncn1 +CCN(CC)C(=O)c1ccc(NC(=O)C(C)C)cc1Cl +CCCCNC(=O)CSc1nnc(C)n1CC +Cc1ccn2cc(C(=O)NCCSc3nccn3C)nc2c1 +CC(C)c1ccsc1C(=O)N1CCN(c2ccc(C#N)cn2)CC1 +Cc1cc(N2CCC(Nc3cnn(CC(F)F)c3)C2=O)n(C)n1 +COc1ccc(C(=O)NCC(N)=O)cc1-c1ccccc1 +O=C(CN1C(=O)COc2ccccc21)c1ccc(Cl)cc1 +CC(C)OC(=O)C(C)N1CC(C(C)C)Oc2cccc(N)c21 +CCC1CCCCN1C(=O)c1cc(N2CCCC2=O)ccc1Cl +C=CCN(CC=C)C(=O)c1cc(OC)ccc1OC +Cc1ccc(-c2ccc(C(=O)NC3CC3)c(=O)[nH]2)cc1 +CC(c1ccccc1)N(C)S(=O)(=O)Cc1ccon1 +CC(Nc1ccc(S(N)(=O)=O)cc1)c1ccccn1 +Cc1cc(C)n(CCC(=O)N(C)Cc2noc(CC(C)C)n2)c(=O)n1 +CCCc1n[nH]c(SCc2cn3ccccc3c2C#N)n1 +CCC(C)NC(=O)c1nn(-c2ccc(OC)cc2)c(=O)n(C)c1=O +C=CCCC1NCCc2cc(OC)c(O)c(Cl)c21 +CNC(=O)c1ccc(CN(C(=O)CNC(=O)OC)C2CC2)cc1 +CCc1ccc(C2CSc3nnc(C)n3N2)cc1 +CC1CN2CC(O)CC2CN1Cc1cc(F)ccc1F +c1cnc(N2CCN(Cc3nnnn3C3CC3)CC2)nc1 +Cc1noc2nc(C(C)C)cc(C(=O)N3CCN(CC(N)=O)CC3)c12 +Cc1nc2ccccc2c2nc(NC(=O)c3ccc(F)cc3)nn12 +CCC(NC(=O)Cc1cn2ccsc2n1)c1ccc(OC)cc1 +Cc1occc1C(=O)NC1CCN(C(=O)C(C)CC2CCCC2)CC1 +COc1cccc(CC(=O)Nc2cc(C)ccc2F)c1 +COc1ccc(OCCN(C)C(=O)NCc2cnc(C)s2)cc1 +Cc1ccc(OCc2nn3c(C#N)c(C)nc3s2)cc1 +O=C(Cn1ccc(-c2ccc(F)cc2)n1)NCCOc1ccccc1 +CCC(O)CN1CCN(C(=O)Cc2nc(-c3ccco3)oc2C)CC1 +COc1cc(NC(=O)c2ccc(C)nc2C)ccc1NC(C)=O +COc1cccc(NC(=O)NCC(O)c2ccc(C)o2)c1OC +CC(O)CN1CCN(C(=O)c2cccnc2N2CCCCC2)CC1 +CSc1cccc(N(C)C(=O)CNC(=O)c2ccsc2)c1 +CCC(C(=O)Nc1cnc(N2CCOCC2)nc1)c1ccccc1 +CC(C)CC(=O)N1CCN(C(=O)Nc2ccccc2)CC1 +CNC(=O)c1cc(C2CCN(C(=O)COC)C2)nc2ccccc12 +CNC(=O)Cc1nc2scc(-c3ccccc3)c2c(=O)[nH]1 +Cc1nc2ccc(NC(=O)CCc3cnn(C)c3)cc2s1 +COC(OC)(OC)C(C)(C)c1ccc2[nH]c(=O)[nH]c2c1 +Cc1cc(C)c2cc(C(=O)NCCCOC(C)C)[nH]c2c1 +O=C1CCCCCN1CCCN1C(=O)c2ccccc2S1(=O)=O +Cn1ncc2c(NC3CCCN(c4ccccc4)C3=O)ncnc21 +O=C(Nc1cc(F)ccc1F)c1scnc1C1CC1 +Cc1n[nH]c(C)c1NC(=O)CCCNC(=O)c1ccsc1 +COc1ccc(N)cc1NC(=O)C(C)OCC(F)(F)F +C=CCN1C(=O)c2ccccc2NC12C(=O)Nc1cc(F)cc(F)c12 +CCOc1cc(NC(=O)C2CCN(C(=O)C(C)C)CC2)ccc1OC +CN(C)C(=O)c1cccc(C(=O)N2CCCSc3ccccc32)c1 +N#CCc1cccc(C(=O)NCc2ccccn2)c1 +CCCC1CN(C(=O)C(C)Oc2ccccc2C#N)CCO1 +CNC(=O)c1cc(Oc2ccc(N)cc2Cl)ccn1 +COC(=O)c1cc(S(=O)(=O)N(C)c2ccc(C)cc2)c[nH]1 +CCCc1ccc(S(=O)(=O)NCc2nc3ccccc3n2C)cc1 +CCCOc1ccc(NS(=O)(=O)c2cn[nH]c2C)cc1Cl +O=C1NCCCC1NCc1ccc(F)c(-c2cccs2)c1 +CC(NC(=O)N1CCN(c2nnnn2-c2ccccc2)CC1)C1CC1 +COc1cc(CNc2ccc(C)c(Cl)c2)ccc1OCC(N)=O +COc1ccccc1OCC(=O)N1CCOC(c2ccccc2F)C1 +CCN1CCC2(CCN(C(=O)c3ccc(C)o3)CC2)C1=O +Cc1cc(C2CCCN2C(=O)c2ccc(C)[nH]c2=O)on1 +COC(=O)NCC(=O)NCc1cccc(-c2nc(C)n[nH]2)c1 +O=C(Nc1nnc(-c2ccno2)o1)C1COc2ccccc2O1 +COCCN(Cc1ccco1)S(=O)(=O)c1cccc(Cl)c1F +COc1cc(S(=O)(=O)n2ccnc2C)c(OC)cc1C +COc1cc(NCC(=O)Nc2cccc(C#N)c2)c(OC)cc1Cl +CNC(=O)C1CCN(C(=O)Nc2nncs2)CC1 +O=C(CS(=O)(=O)c1nccs1)N1CCCCC1 +COc1ccc(NC(=O)c2nn(C)cc2Br)cc1 +CN(C)C(=O)c1ccc(C(=O)N2CCC3CCCCC32)cc1 +COC(=O)c1cc(CNC(=O)Nc2ccnn2C(C)C)oc1C +O=C(NCc1ccsc1)c1cccc(C#CCO)c1 +O=c1cc(NCCCc2ccccc2)nc2ccccn12 +COCc1nc(-c2c(F)cccc2F)sc1CC#N +COc1ccc(CC(=O)n2nnc3ccccc32)cc1OC +O=C(Nc1ccn(Cc2ccccn2)n1)c1cc(=O)c2ccccc2o1 +CC(C)NC(=O)N1CCC2(C1)C(=O)N(CC1CC1)c1ccccc12 +Nc1ccccc1S(=O)(=O)NC(C1CC1)C1CC1 +CC(C)(C)c1noc(CN2CCN(C(=O)N3CCOCC3)CC2)n1 +O=C(Cc1noc(-c2ccoc2)n1)NC1CCCCC1 +CCOc1cc(CNC(=O)c2cccc(C)c2C)ccc1OC +CCc1cc(=O)[nH]c(CN(C)CCc2ccncc2)n1 +CC(NC(=O)NC(C)c1ccc(-n2ccnc2)cc1)c1ccncc1 +CS(=O)(=O)N(CC(N)=O)c1ccc(Cl)c(C(F)(F)F)c1 +C#CCNC(=O)NCc1ccc(OC(F)F)c(OCC)c1 +Cc1ccc(OCC(=O)NC(C)C2CCCO2)cc1 +Cc1ccccc1N1C(=O)CCC1(C)C(=O)NCCC(C)C +CCCNC(=O)CCC(=O)c1cc(F)ccc1F +Cc1noc(C)c1C(C)NC(=O)NC(C)c1cccc(OC(C)C)c1 +Cn1cnnc1SCC(=O)c1ccc(Cl)cc1 +O=C(c1ccccn1)N1CCOCC2(CCN(c3ncccn3)C2)C1 +CCOC(=O)c1nc(C(=O)NC(C)(C)C)oc1C +O=C(c1ccccc1)N1CC2CCCC2(COCc2ccncc2)C1 +O=C(Nc1ccc2c(c1)COC2)c1cc(Cl)ccn1 +Cc1ncsc1C(=O)NCCCN1CCCC1=O +Cn1cc(CN2CCN(CCOc3ccccc3C#N)CC2)cn1 +Cc1ccc(S(=O)(=O)NCc2ccc(C)s2)c(C)c1 +CC(NC(=O)C1(c2ccccc2)CC1)c1ccc(C#N)cc1 +OCC(O)CN(Cc1ccccc1)Cc1nccs1 +COc1cccc2cc(C(=O)N3CCOC4CCCCC43)oc12 +NC(=O)CSc1nc(N)c(NC(=O)c2ccco2)c(=O)[nH]1 +CN(C)S(=O)(=O)c1cccc(CSc2nnnn2C)c1 +CC(Oc1c(N)cc(F)cc1Br)C(=O)N1CCCC1 +Cc1noc(C)c1C(C)NC(=O)NCC1(c2ccccc2F)CC1 +CCOC(=O)c1c(C)[nH]c(C(=O)NCCc2cccc(Cl)c2)c1C +O=C(Cc1coc(-c2cccs2)n1)OCCc1cccnc1 +COc1c(F)cc(NC(=O)c2ccncc2)cc1F +O=C(NC1CCC2CCCCC2C1)c1ccc2[nH]nnc2c1 +O=C1CC2(CCN(S(=O)(=O)C3CC3)C2)Oc2ccccc21 +COc1cc(C(=O)NCc2cccc(C#N)c2)cc(OC)c1OC +Cc1nc(C)c(-c2nn3c(Cc4ccc(F)cc4)nnc3s2)s1 +O=C(NCC1CC1)C1(NCc2cc(F)ccc2F)CCCC1 +Cc1nc2ccccc2n1CCC(=O)N1CCC2(CC1)OCCO2 +Cn1nc(C(=O)NC2CC2)cc1OCC(=O)N1CCCCC1 +Cc1cc(F)ccc1CCNCc1cn(C)nc1-c1cccnc1 +CS(=O)(=O)N1CCc2cc(C(=O)NCc3ccccc3)ccc21 +CC(=O)c1ccc(NC(=O)C2CC=CCC2C(=O)N(C)C)cc1 +Cc1cc(-c2nn3c(CC(C)C)nnc3s2)[nH]n1 +Cc1cccc(OCC(=O)Nc2ccc3[nH]ncc3c2)c1 +Cc1cccc2[nH]c(C3CCN(C(=O)c4cn[nH]n4)CC3)nc12 +CCCCCCNC(=O)C(N)c1ccc(F)cc1 +CCCCN(CC)C(=O)CS(=O)(=O)c1ccc2ccccc2c1 +Cc1nnc(NC(=O)CSc2ccc(-c3ccncc3)nn2)s1 +Cc1ccccc1NC(=O)CCSc1nnc(C(F)(F)F)n1N +N#CCC1COC2(CCN(S(=O)(=O)c3ccccc3)CC2)O1 +CC(NC(=O)C1CCCN(CC(F)(F)F)C1)C1CCCO1 +Nc1ccccc1OCCCOc1ccccc1F +COC(=O)c1cc2n(n1)CCN(C(=O)C(C)N1CCCC1=O)C2 +COCC(=O)N1CCc2ncnc(-c3ccncc3)c2CC1 +CCn1nnc(NC(=O)c2cc(Cl)ccc2Cl)n1 +Cc1ccc(NC(=O)CN2CCOCC2C2CC2)cc1C +NC(=O)Nc1cccc(CNC(=O)c2cc[nH]n2)c1 +O=C(NCc1ccnc(OC2CCC2)c1)C1CC1c1ccco1 +COCCOc1cccc(NC(=O)c2ccc(-n3ccnn3)cc2)c1 +CC(C)CC(=O)N1Cc2ccccc2CC1C(=O)NCC1CCCO1 +Cc1ccc(N)c(OCCOc2ccc3c(c2)OCO3)c1 +Cn1ccc(C(=O)NCc2cccc(N3CCCCC3=O)c2)cc1=O +O=c1nc(Nc2ccc(Br)cc2)cn[nH]1 +CNS(=O)(=O)c1ccc(Oc2cc(C(F)(F)F)ccn2)cc1 +Cc1sc(NC(=O)c2c(Cl)cccc2Cl)c(C(N)=O)c1C +CSc1ncccc1-c1nc(-c2ccc(CNC(C)=O)s2)no1 +CCCn1c(N)c(C(=O)COC(=O)c2ccoc2)c(=O)n(C)c1=O +Cc1ccc(S(=O)(=O)NCc2nc3cccnc3n2C(C)C)cc1 +O=C(NCc1ccc(-n2ccnc2)nc1)Nc1nnc(C2CC2)s1 +COc1ccc(Cl)cc1CNC(=O)C(C)Sc1nncn1C +C#CCN(CC#C)Cc1cnc(-c2ccsc2)s1 +O=C(Nc1cnc2ccccc2c1)c1cc2cccnn2c1 +CC(C)CCC(C)NC(=O)c1ccc(-n2ccnn2)cc1 +O=c1ccc(CNc2cccc(Cl)c2Cl)c[nH]1 +CCOCCCC(=O)Nc1ccc(N2CCNC2=O)cc1 +CCN(CC(C)C)C(=O)c1cccc2c1NCCC2 +C#CCN1CCN(C(C)c2nc(-c3ccccc3C)no2)CC1 +COc1ccc(CCCNc2cccc(O)c2)cc1O +Cc1cc(Br)ccc1-n1cc(C)c(N)n1 +O=C(NCCc1ccccn1)Nc1cccc(OCc2cccnc2)c1 +CCCn1nc(C(=O)Nc2ccc(Cl)cc2F)ccc1=O +O=C(C1CCCC1)N1CCn2c(nnc2-c2ccccc2)C1 +CCOc1nc(N(C)C(C)C(C)(C)C)ccc1N +COCCNC(=O)CCn1c(C)nc2ccccc2c1=O +O=C(OCC1CSc2ccccc2O1)C1COc2ccccc21 +CCCNC(=O)c1nc(N2CCC(C)CC2)c2cnn(C)c2n1 +O=C(Nc1cccc(Cn2cccn2)c1)c1csnn1 +Cc1ccc(C(=O)NCCNC(=O)N(C)C(C)c2cccnc2)cc1 +CC(=O)N1CCC2(CC1)NC(=O)c1sc3ccccc3c1N2 +CCCc1noc(CN2CCN(c3ccccc3OC)CC2)n1 +CCCn1nc(C(=O)Nc2ccc(F)cc2)ccc1=O +O=C(NCc1ncc[nH]1)Nc1cc(F)cc(Cl)c1 +O=C(NCc1cccnc1)C1CCN(C(=O)Nc2ccccc2)CC1 +Cc1ncc2c(n1)CCN(Cc1cc(Cl)c3c(c1)OCCO3)C2 +COc1ccnc(NC(=O)c2cc3cnn(C(C)C)c3nc2C)c1 +CC(=O)Nc1ccc(C#CCNC(=O)C2CCCCC2)cc1 +O=C(C1CCCCC1)N1CCN(Cc2cncs2)CC1 +COc1ccc2c(ccn2CC(=O)NC2C3CCOC3C2(C)C)c1 +NS(=O)(=O)N1CCN(C(=O)CCc2cc(F)ccc2F)CC1 +C=CCOc1ccc(C(=O)NCc2ccncc2)cc1 +COc1ncccc1C(=O)NCc1ccc(C)s1 +C#CCNC(=O)Cn1c(=O)n(C2=CCCCC2)c2ccccc21 +CC(C)=CCC1(CO)CCCN(C(=O)N2CCCC2)C1 +Cc1cc(C)n(CC2(CNC(=O)c3occc3C)CC2)n1 +Cc1ccccc1NC(=O)C(Cc1ccccc1)n1cnnn1 +N#Cc1ccccc1-c1ccc(Cn2ccnc2)cc1 +C#CCN1CCN(C(=O)NC(CC)c2ccc(Cl)cc2)CC1 +CCCc1csc(NC(=O)CNC(=O)c2ccoc2C)n1 +CC(C)CNC(=O)NCc1ccc(S(=O)(=O)N(C)C(C)C)cc1 +Cc1ccc(N2CCC(NS(=O)(=O)c3cccc(F)c3)C2=O)cc1 +O=C1CN(Cc2cncs2)CCN1Cc1ccc(Cl)cc1 +O=C(Nc1cn[nH]c1)Nc1nnc(C(F)(F)F)s1 +O=C(OCc1ccc(F)cc1)c1scnc1C1CC1 +COc1cccc(CNC(=O)c2cccc(OC)c2F)c1 +O=C(Cc1c[nH]c2ccccc12)N(CC(F)(F)F)C1CCOCC1 +CN(Cc1nccs1)Cc1ccccc1OCC(=O)N1CCCC1 +COCCC(=O)N1CCC2(CC1)CN(C(C)=O)c1ccccc1N2 +Nc1cnccc1SCc1nnc(-c2cccs2)o1 +O=C(NC1CCCCCC1)c1cccc(Cn2cncn2)c1 +Nc1oc2c(c1C(=O)c1ccncc1)CCCCC2 +CCn1c(COc2ccc(Cl)cc2)nnc1SCC(=O)NC +COc1cc(CNC(=O)c2cccc(F)c2)cc(OC)c1 +C#CCN(C(=O)c1ccc(CC)c(S(C)(=O)=O)c1)c1nccs1 +COCCOC(=O)c1ccc(OC(F)(F)F)cc1 +OCCCNc1ncnc2c1cnn2-c1ccc(F)cc1 +CCC(CO)NC(=O)c1ncccc1C(F)(F)F +COc1c(F)cccc1-c1nc(C)c(C(C)=O)s1 +Cc1ccc(N)c(Nc2cccc(Br)c2)n1 +Cc1cccc(CNC(=O)Nc2nc(C)n(C(C)C)n2)c1 +Cn1c(CN2CCN(C(=O)C3CCCCC3)CC2)cc(=O)n(C)c1=O +CC(C)NC(=O)c1ccc(=O)n(Cc2ccc(F)cc2)n1 +CC1CCCCN1C(=O)c1ccc(NC(=O)COCC2CC2)cc1 +CC(C)(C)OC(=O)N1CCN(Cc2cncs2)CC1 +CCOc1c(Cl)cccc1NC(=O)N(C)CCC#N +COCC(C)NS(=O)(=O)c1c(C)c(C)cc(C)c1C +CCN1C(=O)Cc2ccccc2C1C(=O)NCCOC +COc1ccccc1NCc1ccccc1C(N)=O +CCN(CC)c1ccc(C(=O)NCc2ccc(C#N)cc2)cc1 +Cc1cccc(OCCNC(=O)NCC2CC2C)c1 +CC1=C(C(=O)N2CCN(C)CC2)C(c2cccnc2)n2ncnc2N1 +Cc1cccc(NC(=O)Nc2ccccc2Br)n1 +O=C(c1ccccc1F)N1CCN(Cc2ccccc2)CC1 +O=C(c1ccc(OC(F)(F)F)cc1)N1CCC(c2cn[nH]c2)CC1 +CC(=O)c1csc(NC(=O)C(C)Oc2ccc(C#N)cc2)n1 +CC(C)NC(=O)Cc1nn(C)c(=O)c2ccccc12 +Cc1cc(C(=O)NCc2cccc(NS(C)(=O)=O)c2)sc1C +Cc1ccc2c(cnn2C(=O)CCC(=O)N2CCCCC2)c1 +O=C(NCC1(O)CCOCC1)Nc1ncc(-c2ccccc2)s1 +CCN(Cc1cccs1)c1nc2sccn2c1CO +CCC(=O)N1CCCN(C(=O)Nc2ccc(OC)c(C)c2)CC1 +Cc1nn(C)c2ncnc(NCC(CO)Cc3ccco3)c12 +CCCCC(=O)Nc1nnc(-c2ccco2)s1 +CN(C)S(=O)(=O)NC1CCN(c2ccc(C(C)(C)C)cc2)CC1 +Cc1nc(-c2noc3ccc(C(=O)N(C)Cc4ccccn4)cc23)co1 +CC(CC(=O)N1CCC(C(N)=O)CC1)C1CCCCC1 +CN(CC(=O)N1CCCC1)c1ncnc2c1cnn2C +Cc1cccc(OCCN2CCCCS2(=O)=O)c1C +O=C(Nc1cc(F)cc(F)c1)c1cn2cccnc2n1 +COc1ccccc1N1CCN(C(=O)c2cc[nH]n2)CC1 +CCc1c(CO)nnn1-c1nc(-c2ccccc2)cs1 +COC(=O)CC1CN(C(=O)Cc2ccc[nH]2)CCO1 +CCCCn1nnnc1SCC(=O)N1CCCC1 +FC(F)(F)c1cccc(CNCc2ncc(-c3cccnc3)s2)c1 +CCNc1cc(NCCNC(=O)Nc2ccccc2)nc(C)n1 +CC(C)NC(=O)c1cccc(NC(=O)c2cccc(F)c2)c1 +O=C1NC(c2cnn(-c3ccc(F)cc3)c2)Nc2ccccc21 +O=C(Nc1nncs1)c1cc2cc(Cl)ccc2[nH]1 +Cn1cc(C(O)CNC(=O)c2ccccc2F)c2ccccc21 +O=C(C1CCc2ccccc2C1)N1CCC(n2cc(CO)nn2)CC1 +COc1ccc(CNc2cccnc2)cc1Br +Cc1cc(C(=O)c2ccc3c(c2)CCCO3)c(C)o1 +O=C(Nc1nccs1)C1COc2ccccc2O1 +CCOc1nc(N(C)Cc2ccc(C)o2)ccc1N +COc1ccc(NC(=O)Cc2ccc(NC(C)=O)cc2)cc1Cl +CN1CCN(C(=O)c2cc3cnn(C)c3nc2N)CC1 +Cn1c(NCCn2c(=O)oc3ccccc32)c(C#N)c(=O)n(C)c1=O +CCOCc1ncn2c1CN(C(=O)NCc1ccccc1)CC2 +CN1CC2(CCCN(c3nccc(C(F)(F)F)n3)CC2)OC1=O +CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc1cn[nH]c1 +Cn1ccc(C(=O)Nc2ccc3scnc3c2)n1 +N#Cc1cccnc1N1CCN(C(=O)NCc2ccccc2F)CC1 +O=C(NCc1ccoc1)NC1CCCc2c1cnn2CCO +CCCCS(=O)(=O)NCC#Cc1cccc(Cl)c1 +Cn1nc(COc2cccnc2)c2c1CCN(Cc1ccco1)C2 +COc1ccccc1NC(=O)C1CC=CCC1C(=O)OC(C)C +Cc1cccc(C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)c1 +Cc1ccc(NC(=O)CNc2ccccc2C(=O)N(C)C)cc1Cl +O=C(Cn1cnnn1)Nc1cccc(N2CCCC2=O)c1 +Cc1ccccc1CNC(=O)c1cccc(S(=O)(=O)NC(C)C)c1 +N#Cc1ccccc1OS(=O)(=O)c1cc(F)cc(F)c1 +O=C(NC(c1ccc2c(c1)OCCO2)C1CC1)N1CCOCC1 +Cc1cccc(C)c1OCC(=O)Nc1cncnc1N1CCCC1 +O=C(Cc1cccs1)Nc1ccc(NCC2CCCO2)c(F)c1 +Cc1cc(C)n2c(CN(CCC#N)Cc3ccccn3)cnc2n1 +O=S1(=O)N=CN(CCOc2ccc(F)cc2)c2ccccc21 +O=C(NCc1cccnc1)c1cc2occc2n1Cc1ccccc1F +COc1ccc2c(=O)c(C(=O)N3CCc4ccccc4C3)c[nH]c2c1 +CC(C)(C)C(=O)NCC(=O)N1CCCC1c1ccc[nH]1 +Cc1c(C#N)nnn1-c1ccc(Oc2ccccc2)cc1 +CCC(=O)c1cccc(S(=O)(=O)NC2CC2)c1 +CC(Nc1ncnc2c1cnn2CCO)c1ccccn1 +COCc1ccc(C(=O)Nc2nc(-c3ccccc3)ns2)cc1 +CS(=O)(=O)c1nsc(NC(=O)c2ccco2)n1 +CSc1nnc2c(n1)OC(C)Nc1ccc(Br)cc1-2 +CCn1cnnc1C1CCN(C(=O)CCc2cccc(F)c2F)CC1 +CCOC(=O)C(C)NC(=O)c1ccc(N(C)C)cc1 +O=c1[nH]c2ccc(S(=O)(=O)N3CCc4ccccc4C3)cc2[nH]1 +CCCCN(C)C(=O)NC1CCN(C(=O)OC)CC1 +Cc1sc2ncnc(NCCN(C)S(C)(=O)=O)c2c1C +CCN1C(=O)CC(c2ccccc2)S(=O)(=O)c2ccccc21 +CC(C)(C)Oc1nc(Sc2ncccn2)ccc1N +CCCc1nnsc1C(=O)NCCCn1ncccc1=O +CCCC1CCC(NS(=O)(=O)c2c(C)nn(C)c2C)CC1 +COc1ccc(CC2CN(C(=O)c3cccs3)CCC2OC)cc1 +Cn1cc(Br)cc1C(=O)NCCc1ccncc1 +O=C(c1nc2c(s1)CCN(Cc1ccccn1)CC2)N1CCCC1 +Cc1noc(NC(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)n1 +CCn1c(CN2CCC(C(N)=O)CC2)nc2cc(F)ccc21 +COC(=O)c1nccc2cc(Br)ccc12 +Cc1csc(=O)n1CCSc1nc2ccccc2s1 +CNS(=O)(=O)c1ccc2c(c1)nc(C(C)C)n2C +CN(Cc1ccccc1)c1nccc2c(N)ccc(F)c12 +Cc1nc(N2CCCCC2)sc1C1Sc2ccccc2NC1=O +N#Cc1cccc(Cn2ccnc2CCN2CCOCC2)c1 +Cc1nn(C)c(C)c1CCC(=O)Nc1cnn(CC2CC2)c1 +CC(C)Cc1cc(C(=O)NCc2noc(C3CCCO3)n2)n(C)n1 +O=C(Nc1nc2cc3c(cc2s1)OCCO3)c1ccc(F)cc1F +CCc1cc2c(=O)n(Cc3nc4ccccc4o3)cnc2s1 +CCc1cc(NC(=O)NC2CCCn3nc(CC)nc32)n(C)n1 +Cc1ccc(C(CNC(=O)N(C)CC2CCC2)N2CCOCC2)o1 +O=C(Cc1ccc[nH]1)Nc1ccc(COC2CCCC2)cc1 +CC(=O)Nc1cccc(-c2nc3ccc(C)cc3o2)c1 +O=C(Nc1cn[nH]c1)NC1CCN(c2ccccc2OC(F)F)C1 +CCCCCS(=O)(=O)N1CCC(C(F)(F)F)CC1 +Nc1ccc2[nH]c(C(=O)NCCC(F)(F)F)cc2c1 +CC=CCCNC(=O)Nc1ccc(C(C)=O)c(C)c1 +CC1(C)CN(C(=O)c2cnn(-c3cccc(Cl)c3)c2)CCO1 +Cc1csc(NS(=O)(=O)c2cccc(N)c2)n1 +COCC(=O)NC(C(=O)NCC1CCc2ccccc2C1)C(C)C +COc1ccc(Cc2nn3cnnc3n(CCO)c2=O)c(OC)c1 +CC(C)CN(CC(C)C)c1ncnc(-n2cnc3ccccc32)c1N +NC(=O)NCc1ccc(C(=O)NC(c2ccccc2)C2CC2)cc1 +CC(=O)c1ccc(N2CCN(C(=O)c3cccc(C)c3C)CC2)cc1 +CCN(Cc1ccc(OC)cc1)C(=O)c1ccc(COC)o1 +COc1ccc(CNC(=O)N2CCN(C(=O)C3CCCO3)CC2)cc1 +O=C(NCc1nc(-c2cccnc2)no1)c1ccccc1C(F)(F)F +Fc1cnc(-c2ccc3c(c2)OCO3)nc1N1CCOCC1 +Nc1cccn2c(-c3ccc(Br)cc3)nnc12 +CC(C)C(NC(=O)c1cccc2cc[nH]c12)C(=O)N(C)C +CCNc1ccc(Cl)cc1C(=O)NC(C)C(N)=O +Cc1cc(C(=O)Nc2ccccc2)nc2nccn12 +COc1ccc(Cl)cc1CN1CCn2c(nn(C)c2=O)C1 +Cc1ccc(Cl)c2c1CCNC2CC1CCOCC1 +Cc1cc(OC(F)F)c(C(=O)N(C(C)C)C(C)C)s1 +O=C(NCC1CC1)N1CCc2ccc(Cl)cc2C1 +Cc1cc(COC(=O)c2cc(-c3ccccc3)[nH]n2)no1 +CCCNC(=O)Nc1sc2c(c1C(N)=O)CCCC2 +CN(Cc1cnn(C)c1)C(=O)CN1C(=O)CCOc2ccccc21 +O=C(C1CCCO1)N1CCN(C(=O)C2COc3ccccc3O2)CC1 +CN(CC(=O)NCC1CCC1)c1ccc(F)cc1 +CSc1cccc(C(=O)Nc2cc(C)nn2-c2ccccc2)c1 +c1cnc(N2CCCC23CCN(c2cccnc2)CC3)nc1 +CC(CC#N)N(C)C(=O)c1cccc(Oc2cnccn2)c1 +N#Cc1cc(-c2ccco2)n(CC(=O)c2ccccc2)n1 +CC(=O)NC(C(=O)Nc1ccc(Br)cn1)C(C)C +COc1cc(NCCC(=O)N(C)C)cc(OC)c1 +CC(C)CC(C#N)NS(=O)(=O)c1ccc2[nH]c(=O)oc2c1 +CC(C)CCNC(=O)Cn1ncc2c1-c1ccccc1OC2 +O=C(NCCC1CC1)N1CCC(OCc2ccc(F)cc2)CC1 +COCC(C)Nc1ncnc(Nc2cc(F)ccc2F)c1N +Cc1nc(CC(=O)N2CCCC(c3cnccn3)C2)cs1 +Cc1ccc(CNCc2ccnc(OC3CCC3)c2)s1 +CCc1c(C(=O)NCc2ncn(C)n2)cnn1-c1cccc(Cl)c1 +COCCn1nc(C)c(NCc2cccc3cccnc23)c1C +Cc1nc2cc(F)cc(C(=O)Nc3cnn(C)c3)c2nc1C +CC(CC#N)N(C)C(=O)Nc1ccc(COC2CCCC2)cc1 +CCC(=O)N1CCCC(c2cnc(Nc3ncccn3)cn2)C1 +COC(=O)C(C)N(Cc1ccccc1)C(=O)c1csnc1C +O=S1(=O)N=CN(c2cccc(F)c2)c2ncccc21 +O=S(=O)(c1c(Cl)cccc1Cl)N1CCc2nocc2C1 +Cc1ccc(OC(=O)CCc2nc(-c3ccco3)no2)cc1C +O=C1CN(C(=O)CSc2nc3cc(Cl)ccc3o2)CCN1 +COc1ccc(Cc2nccn2Cc2cccc(C#N)c2)cc1 +COCc1cccc(NC(=O)NC2CCCc3c2cnn3CCO)c1 +O=C(c1ccc2ccccc2n1)N1CCC(Nc2cccnc2)CC1 +Cc1nnc2sc(-c3cccc(O)c3)nn2c1=O +CC(=O)Nc1cc(NCc2cc(Br)cs2)ccc1F +CC(=O)OC12CCCCCC1C1(O)C(O)CCCC21 +CC(C)OC1CCC(NC(=O)c2cn(C)nc2C(C)(C)C)CC1 +COCc1c(C#N)nnn1-c1nc(-c2ccc(F)cc2)cs1 +CC(=O)N1CC(C(=O)NC(C)CCc2ccco2)Oc2ccccc21 +CCNC(=O)CN(CC)S(=O)(=O)c1ccc(F)c(C)c1 +Cc1c(C(=O)NC(C)CO)oc2ccc(Cl)cc12 +NC(=O)C1CCN(C(=O)CCOc2ccccc2)c2ccccc21 +CSc1cc(C(=O)Nc2nccs2)ccn1 +CN(CCc1ccc(F)cc1)C(=O)NCC1CC1 +CCc1nnc2n1CCN(c1cccc(F)c1C#N)C2 +CC1CCCCC1NC(=O)CSc1nnc(-c2ccncc2)n1C +COC(=O)c1cc(CN2CCOC(c3ccccc3Cl)C2)c[nH]1 +CCc1noc(CN(C)C(=O)Nc2c(C)noc2CC)n1 +CNC(=O)c1ccc(NC(=O)CCc2cccc(OC)c2)cc1Cl +O=C(NCC(=O)c1cccc2ccccc12)c1cc[nH]n1 +CCCN1C(=O)C2(CCCCC2)NC1c1cnc(N2CCCC2)nc1 +CC(C)(C)OC(=O)N1CCC(NC(=O)Nc2ccccc2)CC1 +Nc1cc(C(=O)NC2CC2)ccc1OCc1cccc(F)c1 +CCCCn1c(SCC(N)=O)nc2sc3c(c2c1=O)CCC3 +CCOC(C)c1noc(CNc2cc(S(C)(=O)=O)ccc2F)n1 +NC(=O)c1c(NC(=O)C2CCCO2)sc2c1CCCCC2 +CCN(CC)S(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +COCCC(=O)Nc1cnc(N2CCOCC2)nc1 +Cc1ncc(C(C)NC2CCN(c3ncccc3F)C2)s1 +CCc1ccc(C2COCCN2C(=O)NCc2ccc(C#N)cc2)o1 +COc1ccc(CNC(=O)COC(=O)c2ccccn2)cc1 +Nc1nc2c(c(NC(=O)Nc3ccccc3)n1)CCCC2 +Cc1ccc(F)c(NC(=O)c2ccccc2CSc2ncn[nH]2)c1 +CCCn1nccc1NC(=O)c1cc(C(C)=O)c[nH]1 +O=C(Nc1cc(-c2ccccn2)no1)c1ccsc1 +Cc1noc(COC2CCCN(C(=O)NCCc3ccccc3)C2)n1 +COCC(=O)NCCS(=O)(=O)N1CCc2ccccc21 +O=C(NCc1nnc(-c2ccccc2)o1)c1cc(=O)c2ccccc2o1 +COc1ccc(Br)c(NC(=O)N2CCOC(C)(C)C2)c1 +O=C1CCCCN1Cc1nc(-c2cc3ccccc3o2)no1 +Cn1nc(-c2ccncc2)c(-c2ccccc2F)c1N +Cc1nccc(N2CCCCC2c2cnccn2)n1 +CCCCS(=O)(=O)N1CC=C(c2cn(C)c3ncccc23)CC1 +O=C(Nc1ccccn1)c1cccc(OCc2cscn2)c1 +CC(CCCO)NC(=O)N(C)Cc1ccc2c(c1)OCO2 +CCN(C)C(=O)c1cccc(OC(=O)c2cc3ccccc3o2)c1 +CCOCCOCC(=O)Nc1ccc(C)cc1C +CCn1nc(Cn2cncn2)nc1CN1CCOC1=O +CCC(=O)NC(C(=O)N(C)Cc1sccc1C)c1ccccc1 +CC(C)c1nnc(SCc2cn3ccccc3n2)n1C +CCOc1ccc(F)c(C(=O)N2CCC(OCCOC)CC2)c1F +COc1cc(Cl)c(C)cc1NC(=O)c1cc(=O)[nH]c2ccccc12 +CC(OC(=O)C1=NC=CC1)C(=O)NCc1ccccc1 +COc1ccccc1N1CCN(C(=O)CCCNC(C)=O)CC1=O +O=C(NCc1cnn(-c2ccccc2)c1)c1ccc(-n2ccnc2)cc1 +Cc1noc(C)c1S(=O)(=O)NC1(C#N)CCOCC1 +CCC(=O)NCCOc1ccc(Br)cc1 +Cc1cc(OCC(=O)N(CCC#N)CCC#N)nnc1C +C=CCn1c(COC)nnc1SCc1ccccc1Cl +O=C(COc1ccccc1Cl)Nc1nc(-c2ccccn2)cs1 +CC(C)CCn1c(CCNC(=O)c2cccnc2)nc2ccccc21 +CC(c1cccs1)N(C)CCc1ccccc1N +CCc1noc(CN2CCN(CC(O)c3ccccc3)CC2)n1 +CN1C(=O)CCc2cc(C(O)c3ccco3)ccc21 +Cc1nnnn1-c1cccc(NCC(=O)NC(C)(C#N)C(C)C)c1 +CCC(Oc1ccc(Cl)cc1)C(=O)NCc1ccccn1 +Cc1cc(CC(=O)c2ccccc2Br)[nH]n1 +CC(=O)c1ccc(N2CC3CCC(C2)N(CC2CCC2)C3=O)nc1 +CC(=O)c1c[nH]c(C(=O)Nc2ncc(Cc3ccccc3C)s2)c1 +N#Cc1cccc(CNC(=O)c2ccc(CNC(N)=O)cc2)c1 +Nc1cnc(CCc2ccc(Cl)cc2Cl)nc1 +Cc1csc(CN(C)C(=O)c2cc(CN3CCOCC3)on2)n1 +Cc1cc(C)c(C#N)c(N(C)Cc2ccsc2)n1 +Cc1csc(=O)n1CCn1nnc(-c2ccccc2)n1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N(C)c1cccc(C#N)c1 +CCOc1ccc(NC(=O)c2cc(C)n(C)n2)cc1OC +CCOC(=O)c1nn(-c2ccc(CC#N)cc2)c2c1CNCC2 +Cc1noc(-c2cccc(NC(=O)Cc3ccc(Cl)cc3)c2)n1 +CCc1noc(CC)c1CNC(=O)Nc1cnn(CC(C)C)c1 +COCC(=O)Nc1ccc(C(=O)c2nccn2C)cc1 +COc1cc(C)ccc1S(=O)(=O)Nc1cccnc1 +Cc1cc(C(=O)N2CCCN(S(C)(=O)=O)CC2)sc1C +O=C(CC1Sc2ccccc2NC1=O)OCCc1ccccc1 +COCCCNC(=O)c1c(-c2cccnc2)noc1C +COc1ccccc1-n1c(=O)c2cnc3ccccc3sc=2c1=O +Cc1noc(C)c1C(=O)NCCCc1cccc(Br)c1 +Cc1onc(-c2cccnc2)c1C(=O)NCCc1ccc(Cl)cc1 +CCS(=O)(=O)N1CCc2cc(C(=O)Cn3cnnc3C#N)ccc21 +Cc1ccc(C(=O)NCc2nc(C(=O)N3CCCC3)c(C)o2)s1 +Cc1ccccc1COC1CCN(C(=O)c2cccc(F)c2)CC1 +Nc1c(-c2ccc3c(c2)OCO3)nnn1-c1ccc(O)cc1 +CCn1c(Sc2ccc(C#N)c(Cl)c2)n[nH]c1=O +Nc1ccc2onc(CC(=O)Nc3nccs3)c2c1 +C=CCNC(=O)CCC(C#N)c1ccc2c(c1)OCO2 +Cc1ccc(S(=O)(=O)NCCC(=O)Nn2cnnc2)cc1 +O=C(OCC1CC(=O)N(C2CC2)C1)c1cnn(-c2ccccc2)c1 +COC(=O)Nc1cc(NC(=O)COc2ccccc2OC)ccc1F +O=C(Cn1ncc2ccccc2c1=O)NC(c1ccccc1)C1CCC1 +CCc1nc(CN2CCN(C(=O)NC)CC2)cs1 +Cn1c(SCc2ccccc2C#N)nnc1-c1cccnc1 +CC(C)(C)n1nc(COCc2ccccc2)c(C#N)c1N +CCc1onc(C)c1NC(=O)c1cnc(Cc2ccccc2)s1 +CN(C)S(=O)(=O)c1ccc(-c2cc(O)cc(F)c2)cc1 +CC(=O)c1c(C)[nH]c(C(=O)NCCCC(N)=O)c1C +COc1cccc(C(=O)NCc2nc3ccccc3[nH]2)c1O +CCc1ccc2c(CNc3ccc(C(N)=O)cc3)cc(=O)oc2c1 +N#Cc1cnc2cc(F)cc(F)c2c1N1CCNC(=O)C1 +CC(C)C1OCCC1CNC(=O)c1cccc(-c2ccoc2)c1 +Nc1cc(N)cc(-c2nc3cc4ccccc4cc3[nH]2)c1 +CS(=O)(=O)NC1CCCN(C(=O)NCc2cccc(F)c2)C1 +CCN1CC(C(=O)NCCCc2ccncc2)CC1=O +Cc1ccc(-c2ncco2)cc1NC(=O)CCOCC1CCCO1 +CCNc1ncc(C(=O)N2CC(c3ccccn3)C2)cn1 +Cc1ncc(-c2ccc3c(c2)OCO3)c(-c2nccs2)n1 +CCN(CC)C(=O)CCC(=O)N1CCC(C(=O)N(C)C(C)C)CC1 +COc1cc(CCC(=O)Nc2cnccc2C)cc(OC)c1 +CCn1nc(C)cc1C(=O)Nc1cc(Cl)ccc1Cl +Cc1cc(Nc2nc(-c3cccc(N)c3)cs2)no1 +CCCC1CN(C(=O)Cn2cccnc2=O)CC1NS(C)(=O)=O +COc1ccccc1CNCC(O)c1ccc(F)cc1 +N#Cc1cccc(CN2CC(c3nc(-c4cnccn4)no3)C2)c1 +CCOC(=O)Cn1cc(CO)c2cc(Cl)ccc21 +COc1c(Cl)cccc1NC(=O)NCCCC(N)=O +NC(=O)c1ccc(Cl)c(S(=O)(=O)Nc2ccc(Cl)cc2)c1 +Cc1nn(C)c(C)c1CCNC(=O)c1cn(CC(=O)N(C)C)nn1 +Cc1ccc(NC(=O)CSc2nnc(C)n2C2CC2)c(C)c1 +NC(=O)NC(CC(=O)Nc1ccc(C(N)=O)cc1)c1ccccc1 +COc1cccc(-c2cc(C(=O)Nc3ccccc3F)n[nH]2)c1 +Cc1cc(NC(C)c2cc3ccccc3o2)n2ncnc2n1 +Cc1nn(C)c(C)c1C(C)C(=O)NC1CC1c1ccc(F)cc1 +O=C(OCC1CCCO1)c1cnc(-c2ccccc2)s1 +COc1ccc(-c2nnn(-c3ccc(F)cc3)c2N)cc1F +CSc1ccc(OC(C)C(=O)OCC2(C)COC2)cc1 +c1cncc(COC2CN(Cc3ccncc3)C3CCCOC23)c1 +Cc1ccc(F)c(C(=O)N(C)CC(=O)NC(C)(C)C)c1 +CCN1C(=O)CCc2cc(NC(=O)c3cccc(F)c3)ccc21 +CCC1CN(CC(=O)c2c[nH]c(C(=O)N3CCCC3)c2)CCO1 +Cc1nn(-c2ccccc2)cc1CN1CCOC(C)C1C +CCCn1c(C)nnc1SC(C)C(=O)N(CC)CC +CC1CC(C)CN(C(=O)CNC(=O)c2ccc(F)cc2)C1 +O=S(=O)(Cc1cccc(Cl)c1)N1CCOCC1 +Cc1ccc(-c2cc(C(=O)Nc3nccs3)on2)cc1 +CCOC(=O)C1CCCN1C(=O)CCn1cncn1 +O=C(CC1COCC2CN(c3ccncn3)CC12)N1CCCC1 +Cc1cccc(CS(=O)(=O)NCC#Cc2ccc(N(C)C)cc2)c1 +CC(C)CCCCNC(=O)N(C)Cc1ccccn1 +O=C(c1cccs1)N1CCCC(c2nncn2-c2ccccc2)C1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2ncc(C)s2)c1 +CC1CCCC(C)N1C(=O)c1cccc(OCC(F)F)n1 +Cn1nnnc1Sc1nc2c(cc1C#N)CCCC2 +CNC(=O)c1ccc(Cl)c(NC(=O)c2ccc(C(=O)OC)cc2)c1 +Cc1nn(CC(=O)N(Cc2ccccc2)CC(C)O)c(C)c1Cl +O=C(c1cccs1)N1CCCC1Cc1ccccc1 +CCCCn1nc(C(=O)Nc2cc(Cl)ccc2N(C)C)ccc1=O +O=C(Nc1ccc2c(c1)OCCO2)c1coc2ccccc12 +Cc1noc(N)c1Sc1ccc(Br)cc1 +CC(=O)NCCNC(=O)c1ccccc1NC(=O)c1cccc(C)c1 +C=CCOc1ccccc1C=c1sc2ncnn2c1=O +CCNc1cc2c(nn1)CCN(C(=O)Cn1ccc3ccccc31)C2 +CC(C)Cn1c(SCCC#N)nnc1N1CCOCC1 +CC(Nc1cccc(C(N)=O)c1)c1ccc(C#N)cc1 +Clc1ccc(-n2cccn2)c(NCc2csnn2)c1 +O=C1CN=C(Nc2ccccc2F)N1Cc1ccccc1 +CN(CC(=O)Nc1ccccc1)C(=O)Nc1nnc(C2CC2)s1 +O=C(Cc1cccs1)N1CCN(Cc2ccccc2)c2ncccc21 +O=C(c1c[nH]nc1-c1cccc(Cl)c1)N1CCCC1 +C=CCNC(=O)N1CCN(C(=O)c2ccc(OC)cc2)CC1 +CC(C)c1cc(N2CCN(C)C(CO)C2)ncn1 +COc1ccc(CCNC(=O)c2ccc3cc[nH]c3c2)cc1OC +COc1ccc(CC(=O)N2CCC3C2CCC(=O)N3CC2CC2)cc1 +CCC(C)(CNC(=O)c1ccccc1)N1CCOCC1 +Cc1ccoc1C(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +COCCNC(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CC1CC(c2ccc(C#N)cc2)Cn2nc(N)nc21 +COC(=O)Cc1csc(NC(=O)Cc2ccc(F)cc2)n1 +CCn1cc(S(=O)(=O)NCC2CCCC2)c(N)n1 +COC(=O)CCC(O)c1ccc2c(c1)CC(=O)N2C +Cn1ncc2c(c(-c3ccccc3)nn2Cc2ccccc2)c1=O +CC(C)CCC(C)NC(=O)Nc1cnn(CC(N)=O)c1 +CCCn1nc(C)c(CN2CCN(C(=O)C3CCCCC3)CC2)c1C +O=C(CCN1C(=O)COc2ccccc21)NCCCO +CC1CN(C(=O)CC(C)c2ccccc2)CC(C)O1 +Cc1ccc(C(=O)N2CCCN(c3nccs3)CC2)c(C)n1 +CCc1c(C(=O)Nc2ccccc2OC)cnn1-c1ccc(F)cc1 +Cc1nc(C2CCCN2C(=O)c2cc(C)sc2C)no1 +O=C(NCCN1CCOCC1)Nc1ccc(Br)cc1 +CC(=O)N1CCN(C(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)CC1 +CCCCNC(=O)c1c(-c2ccccc2)nc2sccn2c1=O +Cc1ccc(-c2nnn(CC(=O)NC(C)c3ccco3)n2)cc1 +Cc1noc(CCC(=O)OCCn2c(=O)oc3ccccc32)n1 +CC(C)c1ccccc1NC(=O)CCNS(C)(=O)=O +CCOCc1ccc(CNC(=O)c2c(C)nsc2NC)cc1 +COc1ccc(-c2noc(CNC(=O)C3CC3)n2)cc1OC +O=C(CSc1nnc(-c2cccnc2)o1)c1ccc(Cl)cc1 +CC(=O)N1CCCN(C(=O)Cc2ccc3c(c2)OCO3)CC1 +COCc1nc2nnc(-c3ccnc(N4CCCCC4)n3)c(C)n2n1 +COc1cccc(C(=O)Nc2ccc(NC(=O)NC(C)C)cc2)c1F +COc1ccc(-n2ncnc2Cn2ccccc2=O)cc1 +CCCC(=O)N1CCCC(C(=O)Nc2ccccc2-n2ccnc2)C1 +CCc1nnc(NC(=O)C(C)NC(=O)c2ccccc2)s1 +C=C(C)Cn1c(CCCO)nc2cc(C)c(C)cc21 +COc1ccc(-n2nnc(-c3ccc(F)c(C)c3)c2N)cc1 +Cc1cccc(-c2c(C(F)(F)F)nn(C)c2N)c1 +CC1CCc2[nH]nc(C(=O)NCC3CCCO3)c2C1 +O=S(=O)(CCNc1ccc(Br)cn1)c1ccccc1 +N#Cc1ccc(NC(=O)Cn2cnc3sccc3c2=O)cc1Cl +C#Cc1cccc(N(Cc2cccs2)C(=O)CCOCC)c1 +CCc1nc(C2CC2)c(-c2nnc(NC(C)C)s2)s1 +Oc1ccc(C2NCCc3cccc(F)c32)c(F)c1F +COc1cccc2cc(-c3nnc(NC(C)=O)o3)oc12 +CN1CCN(C(=O)c2ncn(-c3ccccc3)n2)c2ccc(F)cc21 +Cc1ccnn1CCC(=O)N1CCCCC1c1nc2ccccc2[nH]1 +CCc1oc(C(=O)OC)cc1COc1cccc(CO)c1 +CN(C(=O)CCNC(=O)c1ccsc1)C1(C#N)CCC1 +Cc1cccc(CNC(=O)c2ccnc(-c3ccsc3)c2)c1 +COc1cc(CNC(=O)NC(C)c2cccc3ccccc23)ccn1 +O=C(NCc1ccoc1)c1ccc(-c2cnco2)cc1 +CCCC(=O)N1CCCCC1C(=O)N(C)CCOC +Cc1cccc(CN2CCN(C(=O)CCCn3cccn3)CC2)c1 +COC(=O)c1ccc(NC(=O)COc2ccc(F)cc2C(C)=O)cc1 +O=C(Nc1ccccn1)C(Cc1ccccc1)n1cnnn1 +CNC(=O)C(C)Nc1cc(C)c(Cl)cc1OC +NC(=O)c1cccnc1N1CCN(C(=O)c2ccc(F)cc2)CC1 +CC1CC(C)CN(C(=O)Cn2c(=O)oc3cc(Cl)ccc32)C1 +Cn1ncn(Cc2nnc(C(=O)NCc3ccc(F)cc3)s2)c1=O +CCC(C(N)=O)N1CCN(c2cccc(Cl)c2)CC1 +Cc1cnc2c(S(=O)(=O)N3CC(C)OCC3C)cccc2c1 +CC(=O)c1c(C)[nH]c(C(=O)N2CCC(Oc3ccccc3)CC2)c1C +Cn1nc(C(=O)N2CCOCC2)c2c1CN(Cc1ccncc1)CC2 +CCOc1ccccc1CNC(=O)c1cc(C)n(C2CC2)c1C +CC(=O)NCc1ccc(C(=O)OCC(=O)Nc2cccc(C)c2)cc1 +CCCNC(=O)Cn1nnc(CO)c1C1CCC1 +CCOC(=O)NCCC(=O)NC(C)c1ccc(C)s1 +CCCCN(CC(N)=O)S(=O)(=O)c1ccc(F)cc1Cl +O=C(COc1ccccc1F)NCc1cnn2ccccc12 +CCC(Oc1ccccc1)C(=O)NCc1ccccc1 +O=C(Cc1ccccc1)NCC(=O)Nc1ccccc1 +CCOc1ccc(S(=O)(=O)NCCc2c(C)nn(C)c2C)cc1 +CN(Cc1cccc(C#N)c1)C(=O)NCc1ccc(-n2cccn2)cc1 +Cc1cc(C(=O)Nc2ncc(Cc3ccc(F)c(F)c3)s2)nn1C +COC1(CNC(=O)Nc2cnc(C3CC3)nc2)CCC1 +O=C(NCC(O)CO)Nc1ccc(Cl)c(Br)c1 +CCn1cc(NC(=O)NCCNc2ncccn2)cn1 +c1cn(-c2ccc3c(c2)OCO3)c(-c2cnc(N3CCCC3)s2)n1 +COCc1ccc(NCc2ccc(OC)c(O)c2)cc1 +Cc1cc2ccccc2n2c(=O)n(Cc3cccnc3)nc12 +Cc1cccc(NC(=O)c2ccc(-c3cccs3)nc2N)n1 +COC(=O)C(CC(C)C)NC(=O)c1ccccc1F +CN(CC(C)(CO)CO)C(=O)Nc1cc(Cl)cc(Cl)c1 +COC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(C(=O)OC)cc1 +COc1ccccc1NCC(=O)Nc1c(C)cccc1C(C)C +CCCNC(=O)C1CCc2nc(N3CCCCC3)ncc2C1 +CCCC(=O)Nc1ccc(OC)c(OCC(F)(F)F)c1 +Cc1cc2c(cc1O)C(c1cc(Cl)ccn1)NCC2 +COc1cc(OC)c(C(O)C(=O)N(C)C)c(OC)c1 +Cc1n[nH]c(C)c1CCC(=O)Nc1cc(Cl)c(N)c(Cl)c1 +CC1(C)CN(C(=O)Cc2cccnc2)CC1(O)C1CC1 +COCc1cccc(NCc2ccc(-n3ccnc3)cc2)c1 +Cc1c(C(=O)NCC(C)c2cccs2)cnn1-c1ccc(F)cc1 +Cn1cnc(CNC(=O)Nc2ccc(F)c(Cl)c2)n1 +Cn1cc(C(=O)NCc2cnn(-c3ccccc3)c2)c(C(C)(C)C)n1 +Cn1c(=O)[nH]c(=O)c2c1nc(N1CCCC1)n2CC(O)CO +Cc1ccccc1-n1ncc2c(=O)n(Cc3cccc(F)c3)cnc21 +COc1ccc(-n2ccc(CNC(=O)NC3CCCC3)n2)cc1 +O=C(Cc1ccc(Cl)cc1)N1CCc2c([nH]c3ccnn3c2=O)C1 +CN1C(=O)Cc2cc(NS(=O)(=O)c3ccccc3)ccc21 +CCC1CN(C(=O)NCc2ccnc(OC)c2)CCO1 +CNC(=O)CCNC(=O)c1cccn(Cc2cccc(C)c2)c1=O +Cc1ccc(N2CCCC(NCc3nc4ccccc4s3)C2)nn1 +COc1ncccc1C(=O)NCC(C)(C)c1cccc(C)c1 +Cc1nc2sc(C(=O)c3ccccn3)c(N)c2c(C)c1C +COc1ccc(F)cc1C(O)CNC(=O)c1cccc(F)c1 +Cc1[nH]c(C)c(S(=O)(=O)NC2CC2)c1C(=O)N1CCCCC1 +Cc1nn(C)c(C)c1CNC(=O)c1nccc2cccc(N)c12 +CN(Cc1cc(Cl)cc(Cl)c1)C(=O)c1ccc[nH]c1=O +OC1CN(c2ccc3nnc(-c4cc(Cl)cc(Cl)c4)n3n2)C1 +Cc1cnn(CCC(=O)Nc2ncc(C)s2)c1 +Cc1ccc(NC(=O)C2CCN(S(C)(=O)=O)CC2)nc1 +CC(C)NC(=O)CSc1nnnn1-c1ccccc1C(F)(F)F +COC(=O)c1cc(Nc2ccccc2)c(=O)n2c1CCC2 +Cc1nc2cc(C(=O)Nc3ccc4c(c3)CCC(=O)N4C)ccc2n1C +Cn1nc(-c2ccccc2)cc1-c1nc2c([nH]1)CC(C)(C)CNC2=O +c1cn(-c2ccc(-n3cnnn3)cc2)c(C2CC2)n1 +Cc1nc(C)c(CNCc2ccc(Br)cc2)s1 +CNc1ncc(CN(C)C(=O)c2cccc(-n3cccn3)c2)cn1 +O=C(Nc1ccc(CC(=O)N2CCCC2)cc1)c1ccc(F)c(F)c1 +O=C(NCc1ccccc1)c1ccc(NC(=O)C2CCC2)cc1 +CCNC(=O)c1cccc(NC(=O)CNc2cccc(C)c2C)c1 +Cc1ccc(NC(=O)CCCNC(=O)OC(C)(C)C)cc1 +CC(C)(C)c1n[nH]c(C2CN(CCc3ccccn3)CCO2)n1 +Cc1nc(-c2ccsc2)sc1C(=O)N(C)CCOCC1CC1 +COc1cccc(OC)c1-c1nnc2c(N)cc(Br)cn12 +COc1cc(F)c(NC(=O)c2cnn(-c3ccccc3)c2)cc1OC +Cc1cccc(Cl)c1NC(=O)N(C)Cc1cccnc1 +CCNc1cccc(C(=O)N2CCCCC2CO)n1 +c1csc(C(CNc2nc(C3CC3)no2)N2CCOCC2)c1 +Fc1ccc(-c2cc(CC3(NCc4cccnc4)COC3)no2)cc1 +CCCN(CC(=O)N(C)C)C(=O)c1cc(-c2cccc(Cl)c2)no1 +CC(=O)N(Cc1ccc(NC(=O)NCCC(C)C)cc1)C1CC1 +Cc1cc(C(=O)NCC2COc3ccccc3O2)on1 +Fc1ccc(Cl)c(-c2nnc3sc(Cn4cccn4)nn23)c1 +CCn1c(N)nc2cc(C(=O)N3CCC(n4cnnc4)CC3)cnc21 +N#Cc1cccc(S(=O)(=O)Oc2ccc(F)c(Cl)c2)c1 +CC(C)N(CC1CC1)c1ccc2ncccc2c1N +Cc1cccc(C(=O)Nc2ccc(NCC(=O)N(C)C)cc2)c1 +N#CC(CC(=O)N1CCCCCC1)c1ccc(F)cc1 +O=C(c1ccc(Cl)cc1F)N(CCO)C1CC1 +NS(=O)(=O)c1cccc(NS(=O)(=O)c2cc(F)cc(F)c2)c1 +CN(C)c1cccc(C(=O)Nc2cc3c(cc2Cl)OCCCO3)c1 +Nc1c(Sc2ccccc2)ncnc1N1CCOCC1 +Cc1ccc2[nH]c(C(=O)N3CCC(c4nnc5n4CCC5)CC3)cc2c1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3ccoc3)CC2)s1 +CCN(CC)C(=O)CCn1cnc2ccccc2c1=O +COc1ccc(C2COc3c(ccc4c3OCO4)C2=O)cc1 +CCNC(=O)NC1(C(=O)NCC(C)(C)c2ccncc2)CCCC1 +COc1ccc(SCC(=O)NC(C)C(C)C)cc1 +O=c1c2c([nH]c3cc(-c4ccc(Cl)cc4)nn13)CCC2 +CCc1nnc(NC(=O)CCC(=O)c2ccc(C)cc2)s1 +CCOc1ccc(-n2nc(CO)cc2C2CC2)cc1 +CCOC(C)c1noc(CSc2nccn2C)n1 +O=C(NCc1ccc(Oc2ccccc2)nc1)c1cnn2cccnc12 +Cc1nnc(CN(C)C(=O)NCc2cccc(NC(C)C)c2)n1C +CCOC(=O)c1cnc2nc(C)nn2c1-c1ccccc1 +CSc1ccc(N2CC(C(=O)NCC(C)O)CC2=O)cc1 +COCCNC(=O)N1CC(c2nc(-c3ccco3)no2)C1 +N#Cc1ccc(-n2c(-c3ccncc3)nc3cccnc32)nc1 +CCOC(=O)c1nnn(-c2nonc2N)c1-c1ccc(C)cc1 +C=CCn1cnnc1SCC(=O)c1ccc(F)c(F)c1 +COc1cccc(C2Nc3ccccc3C(=O)N2C)c1OC(F)F +CN(C)C(=O)N1CCN(C(=O)Nc2ccc(CC#N)cc2)CC1 +CC(=O)c1cccc(NC(=O)N2CCCC2C(=O)NC(C)(C)C)c1 +CC(=O)c1ccc(F)cc1NC(=O)c1cc(-n2cccn2)ccn1 +Cc1ccnc(NC(=O)c2cc(S(=O)(=O)NC3CC3)ccc2C)c1 +CCNC(=O)NCc1c(CC)c(CC)n[nH]c1=O +CC(=O)c1c(C)nc2nc(COc3cccc4cccnc34)nn2c1C +OCc1cnnn1Cc1c(Cl)cccc1Cl +C=CCN(Cc1ccc(OC)cc1)C(=O)C1CCCN1C(=O)C(C)C +CCC(=O)c1cccc(S(=O)(=O)N2CCC(C)CC2)c1 +CCCN(CC1CC1)C(=O)c1ccc2ccccc2n1 +CC(=O)NCCC(=O)OCc1nc(-c2ccccc2)no1 +OC1CCC(Nc2nccc(-c3cnn(-c4ccccc4)c3)n2)CC1 +Cn1cnnc1-c1cccc(NC(=O)c2ccc(F)cc2F)c1 +O=C(c1cc(F)cc(F)c1)N1CCn2c1nc1ccccc12 +COc1ccc(C)cc1NS(=O)(=O)c1ccc(F)cc1 +O=C(C1CCCN1C(=O)C1CC1)N1CCCc2cc(Cl)ccc21 +O=C(CCC1CCCCO1)NCc1cnn(-c2ccc(F)cc2F)c1 +CCC(C)C(NC(=O)Cn1cnc2cc(F)ccc2c1=O)C(=O)OC +Cc1nn(CC(=O)OC(C)C)c(C)c1CN1CCC2(C1)OCCO2 +CSc1ccc(NC(=O)C(C)Sc2nnnn2C)cc1 +CCN(CCCO)S(=O)(=O)c1ccc(F)c(C)c1 +COCCNC(=O)Nc1ccc(CC(=O)Nc2ccccc2F)cc1 +N#CCOc1cccc(CC(=O)Nc2ccc(N3CCCC3=O)cc2)c1 +CCOC(=O)N1CCC(OC(=O)c2cc(C)n(C(C)C)c2C)CC1 +O=C(NCCC(=O)N1CCCC1)c1c[nH]nc1-c1ccccc1F +O=C(Nc1ccc2c(c1)CCC2)c1ccc2c(c1)OCO2 +CCN(CC(=O)N(C)C)c1ccc(F)cc1CO +COc1ccc(Cl)cc1C(C)C(=O)N1CCNCC1 +COc1cc(OC)cc(-c2noc(CCNC(=O)c3ccco3)n2)c1 +OCc1ccc(CNc2cnn(Cc3ccc(Cl)cc3)c2)o1 +Nc1cccc(-c2nc(-c3ccncc3)cs2)c1 +N#CC(CC(=O)NCc1cccnc1)c1ccccn1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3ccn(CC(F)F)n3)cn2)n1 +COCc1cccc(CNC(=O)Nc2cc(C(N)=O)ccc2C)c1 +Cc1cc(C(=O)N2CCN(c3nccc4occc34)CC2)on1 +O=C(CNC(=O)c1ccccc1)NCc1cccnc1 +CCCCn1cccc(-c2csc(NCC(C)C)n2)c1=O +O=C(CSc1ncnc2nc[nH]c12)N1CCCc2ccccc21 +Cc1cc(NC(=O)C2CN(C(=O)c3cnccn3)C2)c2ccccc2n1 +Cc1cc(C)c(C)c(-c2nc3cc(CO)ccn3c2N)c1C +Nc1cc(C2CCN(C(=O)NCCc3ccccc3)CC2)no1 +CC(C)c1ncncc1C(=O)NCCNc1cnccn1 +CS(=O)(=O)NCCNC(=O)c1cccc(Cl)c1 +CC1CCCN(C(=O)CNc2cccc(F)c2F)C1 +O=C1NC2C(NC(=O)N2c2ccccc2)N1c1ccccc1 +COc1ccc(C)cc1NC(=O)COC(=O)c1cccc(N(C)C)c1 +Fc1ccc(CNCc2ccncc2)c(F)c1Cl +COC(=O)c1sc2csc(SC)c2c1N +O=S(=O)(NCC#CCOc1ccc(F)cc1F)C1CC1 +CC(C)CCCNC(=O)NC(c1ccc(F)cc1)c1nccn1C +COc1cccc(-n2cnc3sc4c(c3c2=O)CCC4)c1 +CC=CCC(=O)Nc1ccnn1Cc1cccc(Cl)c1 +Cc1ncc(CC(=O)n2cc(C(=O)c3cc(F)ccc3O)cn2)s1 +Cc1cc(N)nc(SCC(=O)N(CCC#N)CCC#N)n1 +CN(C)c1ncnc2c1CCN(C(=O)C1CCCO1)CC2 +CCOc1ccc(CC(=O)Nc2cccc(CO)n2)cc1 +O=C(c1cc2cc(F)ccc2[nH]1)N1CCN(C(=O)C2CC2)CC1 +CNC(=O)c1cc(Cl)ccc1NC(=O)C1(C)CC1(Cl)Cl +Cc1noc(CNC(=O)CCSc2ccccn2)n1 +O=C(Cc1cccc(F)c1)N1CCC(Oc2cccc(F)c2)CC1 +O=C(Nc1ccc(F)c(S(=O)(=O)NC2CC2)c1)C1CCOCC1 +CN(Cc1ccccc1)S(=O)(=O)Cc1ccc(F)cc1 +CN(Cc1cccc2ncccc12)C(=O)c1cccc(-n2cnnc2)c1 +COC(=O)c1cc(NC(=O)C2CCCO2)cc(C(=O)OC)c1 +O=C(NCc1ccccc1F)c1ccc(C(F)(F)F)nc1 +C#CCN(CC)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O +O=C1COc2cc(C(=O)N3CCC(n4cccc4)CC3)ccc2N1 +Cc1csc(C(=O)NCCCOc2cccc3cccnc23)c1 +Cc1ccc(CN(C)C(=O)c2ccc(OC(F)(F)F)cc2)o1 +CCOC(=O)C(C)(C)N(C)Cc1cccc(-n2cccn2)c1 +Cc1ccc(C(=O)Nc2cc(N)c(F)cc2F)s1 +Cc1cc(C(=O)OCCN2CCOC2=O)c2c(C)noc2n1 +O=C(CNS(=O)(=O)c1ccc(F)cc1)N1CCCCCC1 +CCN1CCN(S(=O)(=O)c2cnn(C)c2)CC1 +NC(=O)c1csc(C(=O)NCc2ccc(F)cc2C(F)(F)F)c1 +Cc1cccc(NC(=O)Cn2c(-c3ncccn3)noc2=O)c1C +Cc1cc(CN2CCN(C(=O)NCc3cnn(C)c3)CC2)on1 +Nc1ccccc1CSc1nnc(C2CC2)n1C1CC1 +CNC(=O)CSc1nnc(-c2ccc3c(c2)OCO3)n1C +O=C(CCC1CCCC1)N1CCN(c2nc3ccccc3o2)CC1 +Cc1c(NCc2ccc(OC(F)F)c(F)c2)cccc1C(N)=O +CC1c2cccn2CCN1C(=O)NCc1ccc(F)cc1 +COc1cc(OC)c(NC(=O)c2ccc3ncccc3c2)cc1F +O=C(Nc1cccc(CC(F)(F)F)c1)N1CCOCC1C1CC1 +Cn1ncc(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1N +COc1cc2cc3c(=O)[nH]c(-c4ccc(C)cc4)nc3nc2cc1OC +O=C(CCc1nc2ccccc2[nH]1)N1CCc2ccccc21 +CC(C)(C)c1ccc(C(=O)Nc2ccccc2)c(N)n1 +CC(C)c1noc(CCCC(=O)Nc2nc3c(s2)CCC3)n1 +Cc1noc(C)c1C(=O)Nc1nc(-c2ccccn2)cs1 +CSc1cccc(NC(=O)c2nc(C)n(-c3ccc(F)cc3)n2)c1 +Cc1cc(NC(=O)NCCN2CCN(c3ccccc3)CC2)n(C)n1 +CC(=O)c1ccc(N2CCC(NC(=O)c3ccccn3)C(O)C2)nc1 +C#CCNC(=O)c1ccc(S(=O)(=O)Nc2ccc(C)c(C)c2)cc1 +Cc1cc2c(cc1C)N(Cc1cccc(N)c1)CCN2 +CCc1nc(CNc2cc(Cl)ccc2-n2cccn2)no1 +COc1cccc(S(=O)(=O)N(Cc2ccsc2)C2CC2)c1 +COc1ccc(C2CC(C)N(c3nc(N)nc4[nH]cnc34)C2)cc1 +Cc1ccncc1NC(=O)N(CCC#N)Cc1ccccn1 +O=C(Cc1ccc(F)c(F)c1)N1CCN(Cc2cccs2)CC1 +CC(C(=O)N(C)C1CCCCC1)S(=O)(=O)c1nccn1C +CSc1nc(C)cc(C(=O)NC2CCCCC2)n1 +CC(C)CNC(=O)NCc1ccc(OCC(F)(F)F)cc1 +Nc1nc(NCc2ccccc2)nc(-c2ccccc2F)n1 +Cc1cccn2cc(CC(=O)Nc3nc4ccccc4[nH]3)nc12 +O=C(Nc1ccc(N2CCCC2)nc1)c1cc2ccccc2[nH]1 +Fc1ccc2c(c1C(F)(F)F)C(C1CCCO1)NCC2 +COc1ccc(C(C)NC(=O)c2ccsc2)cc1 +Cc1cc(S(=O)(=O)N(CCO)C2CC2)ccc1F +O=C(OCc1ccsc1)c1ccc(-n2cnc3ccccc32)nc1 +NC(=O)c1ccc(S(=O)(=O)NC2CCCCCC2)cc1 +Cc1ncc(C(C)NCc2ccc(F)c(Cl)c2)s1 +O=C(CCCNC(=O)c1ccsc1)NCc1ccccc1F +O=C(Nc1cnn(CC2CC2)c1)c1ccc(Cl)cc1 +Cc1ccc(C(C)C)cc1OCC(=O)N(C)Cc1ccncc1 +CN(Cc1ccccc1-n1cccn1)Cc1cccn1C +CC(=O)c1cccc(S(=O)(=O)Oc2ccc(F)c(F)c2)c1 +Cc1ccc(Nc2nc(N3CCOCC3)nc3c2cnn3C)cc1 +O=C(CSc1ccncc1)N1CCC(=Cc2ccccc2)CC1 +Cc1noc(-c2cccc(F)c2)c1C(=O)NCc1cccs1 +CCNC(=O)N1CCc2ccc(NCc3ccc(OC)c(F)c3)cc21 +Cc1ccc(S(=O)(=O)CCC(=O)NCCc2ccccc2)cc1 +CCc1cc(C(=O)N(CCC#N)CCC(F)(F)F)sc1C +O=C(c1cn(-c2ccc(Br)cc2)cn1)N1CCC(O)C1 +CC(=O)Nc1nnc(-c2ccc(Cl)cc2)s1 +O=C(Cc1cccn1-c1ccc(F)cc1)NCc1ccccn1 +Cc1c(C(=O)NCc2ccncc2)nnn1-c1ccc(Cl)cc1 +O=C(CCC1Cc2ccccc2NC1=O)Nc1ccc2c(c1)OCO2 +CCN1C(=O)C(c2ccccc2)Oc2ccc(CO)cc21 +COc1ccccc1N1CCN(C(=O)c2cccnc2)CC1 +Cc1ccc(CO)cc1Nc1ncnc2onc(C)c12 +CN(C)C(=O)CCc1cccc(NC(=O)OC(C)(C)C)c1 +Cc1ccc(OCCn2ncc3ccccc3c2=O)cc1 +Cc1ccc(-c2ccsc2C(=O)NCCO)cc1 +Cc1c(NC(=O)c2cc(C(C)C)on2)c(C(=O)N(C)C)nn1C +O=C(COc1ccc(Cl)cc1)OCC(=O)N1CCOCC1 +Cn1cncc1-c1nnc(C2CCN(Cc3ccccc3F)C2)o1 +Cc1nn(C)c(C)c1CN(C)C(=O)c1c(Cl)cnn1C +Cc1cc(C)nc(SCCCNC(=O)Nc2nccs2)n1 +Cn1cc(NC(=O)CCc2ccc(-c3ccccc3)[nH]2)ccc1=O +c1ccc2c(c1)CNC(c1nnc3ccccn13)C2 +Nc1cnn(Cc2ccc(C(=O)N3CCCC3)o2)c1 +CC1CCC(N2CCN(C(=O)COc3ccccc3)CC2)CC1 +CCn1nnc(NC(=O)c2cccc(Cl)c2)n1 +Cc1cc(N)c2c(Br)cnc(NCCO)c2c1 +CCC(C)N(C)C(=O)c1ccc(F)c(S(=O)(=O)N(CC)CC)c1 +Cc1nn2cnnc2c(C)c1CCC(=O)NC1CCCC1 +O=C(NCCO)NCCc1cc(F)c(F)c(F)c1 +Cc1oc(S(N)(=O)=O)cc1C(=O)NCCc1c(F)cccc1F +CCc1ccccc1NC(=O)NCCCNS(C)(=O)=O +CCN(CC(C)C#N)C(=O)c1cccc(F)c1NC +COc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)cn1 +CCc1onc(C)c1NC(=O)NC(C)Cn1cncn1 +COc1c(OC(F)F)ccc2c1C(CN(C)C)NCC2 +Cc1cccc(C(C)C)c1NC(=O)Cn1nc(C)c(Cl)c1C +CCC(C)C(NS(=O)(=O)c1cccnc1)C(N)=O +C=CCNC(=O)N1CCC2CC(=O)N(C3CC3)CCC2C1 +COc1ccccc1OC1CCN(C(=O)C(O)c2ccccc2)CC1 +Cc1cc(C(=O)NCC(=O)NCC(=O)N2CCOCC2)nn1C +O=C(Nc1cc(Cl)c(Cl)cn1)c1ccc(-n2ccnn2)cc1 +O=S(=O)(NC(Cc1ccc(F)cc1)c1ccccc1)C1CCOC1 +CCCC(=O)NCC(=O)Nc1cc(Cl)c(O)c(Cl)c1 +CN(Cc1cccs1)C(=O)c1cc2cc(F)ccc2[nH]1 +COc1ccc(-c2ccc(C(=O)NC(C)CO)o2)cc1Cl +Cc1cnn(CC2CCCN2C(=O)c2cc(F)c(F)c(F)c2)c1 +CCCNC(=O)C1COC2(CCCCC2)N1C(=O)c1ccccc1C +Cc1noc(C(C)N2CCN(C(=O)C3CC3)CC2)n1 +CCN(CC)C(=O)CCCNC(=O)c1cc2ccc(Cl)cc2[nH]1 +CC(C)c1ccc(-c2ccc(C(=O)NCCO)o2)cc1 +Cn1ncc2c(=O)c(C(=O)N3CCc4c(F)cccc4C3)c[nH]c21 +Cc1nc(NC(=O)C2CC2)sc1C(=O)Nc1cccc(Cl)c1 +CCCN(CC1CC1)C(=O)NCc1ccc(C(=O)N(C)C)cc1 +CC(=O)N1CCC2(O)CCN(c3nnc(C4CCC4)o3)CC2C1 +CN(C(=O)Cn1ncc(=O)c2ccccc21)c1ccccc1 +Cc1cc(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)no1 +CCC(CC)c1cc(CNc2ccc(C#N)cn2)on1 +Cn1c(=O)c2c(ncn2CCC(=O)NC(C)(C)C)n(C)c1=O +CC(=O)N1CCCC1C(=O)c1ccc(C(C)(C)C)cc1 +COC(=O)Cn1c(C(F)(F)F)nc2cc(O)ccc21 +COC(=O)CC1CN(Cc2c(Cl)ccc3cccnc23)CCO1 +CCn1cc(C(=O)Nc2cc(-c3ccncc3)ccc2C)cn1 +Cc1nnc2n1CCN(Cc1nc(-c3ccc4c(c3)OCO4)no1)C2 +CC(C(=O)Nc1cccc(F)c1)N1CCN(C(=O)C2CC=CC2)CC1 +Cc1cc(NC(=O)c2ccco2)n(-c2nc3ccccc3[nH]2)n1 +COC(=O)c1ccsc1NC(=O)c1cc[nH]n1 +COC(=O)c1sc2ncnc(Nc3ccc(O)cc3)c2c1C +CC(Sc1nccn1C)C(=O)NC(C)(C#N)C(C)C +CCC(C)NC(=O)CN1C(=O)C(C)Oc2cc(O)ccc21 +CC(c1cccnc1)n1c(N)nc2cc(Cl)ccc21 +CC(C)N(C(=O)c1cc(F)ccc1F)C1CCCC1 +Cc1cnn(CCC(=O)N2CCN(CC(C)O)CC2)c1 +Cc1ccc(Oc2ccc(NC3CCOC3=O)cc2)nc1 +Cc1nc(C(C)C)c(-c2nn3c(-c4cnn(C)c4)nnc3s2)s1 +COc1ccc(CC2CCN(C(=O)Cn3cc(C)cn3)CC2)cc1 +Cc1ccsc1C(=O)Nc1ccc(-n2ccnc2)nc1 +CCN(Cc1nccn1Cc1ccc(C)cc1)C(=O)c1ccco1 +CCOc1ccc(C(=O)N(C)C)cc1Br +COCCC1(O)CCN(C(=O)c2ccc3cccc(F)c3n2)CC1C +O=C(Cn1c(=O)[nH]c2ccccc21)N=c1[nH]c2ccccc2[nH]1 +O=C(Oc1ccc2cn[nH]c2c1)C1CCOc2ccccc21 +Cc1ccccc1OC1CN(C(=O)c2c(C)[nH]c3c2C(=O)CCC3)C1 +O=C(C1CCN(Cc2nc3ccccc3[nH]2)CC1)N1CCCCCC1 +CCOC(=O)C1(NS(=O)(=O)c2ccc(C)s2)CCCCC1 +NC(=O)Cn1ncc(N2CCNC(=O)C2)c(Cl)c1=O +O=C(C1CCC(O)CC1)N1CCC(C(O)Cc2ccccc2)CC1 +Cc1cccc(C(=O)NCC(C)N2CCOCC2)c1 +Nc1ccc2c(C(=O)Nc3ccc4c(c3)OCCO4)nccc2c1 +CCn1ccc2sc(C)c(C(=O)N3CCOCC3)c2c1=O +Cc1c(C(=O)NCc2ccc(F)cc2)nnn1Cc1ccccc1 +CC(NC(=O)c1c[nH]nc1-c1ccccc1F)C(=O)NC(C)(C)C +CC=Cc1ccc(OC(=O)C(C)NC(=O)c2ccco2)c(OC)c1 +CCOCCNC(=O)N1CCN(C(=O)c2ccc(CC)cc2)CC1 +CCNC(=O)c1cccc(NC(=O)c2ccccc2C(F)(F)F)c1 +O=C(NCc1nc(-c2ccccc2)no1)c1cn(-c2ccccc2)nn1 +CCOCC1CCCN(C(=O)c2cc(Br)ccc2F)C1 +CCOc1ccc(C(O)CNC(=O)c2ccccc2F)cc1 +CCOc1ccc(NC(=O)CCn2c(C)csc2=O)c(C)c1 +Cn1cc(C(N)=O)cc1C(=O)Oc1ccc(Br)cc1 +CCCn1nccc1NC(=O)c1cnc2ccc(C)cn2c1=O +c1ccc(CCc2n[nH]c(Cc3ccc(-n4cnnn4)cc3)n2)cc1 +Cc1cccc(NC(=O)C(NC(=O)c2c(F)cccc2F)C(C)C)n1 +CCOc1ccccc1NC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +Clc1ccc(-c2nc(Cc3ccccc3)no2)nc1 +CNc1ncccc1C(=O)N1CCOC(C(F)(F)F)C1 +CCN(CC)C(=O)COc1ccc(C(C)O)cc1 +N#Cc1ccccc1OCC(=O)Nc1ccc2[nH]ncc2c1 +OCCCc1csc(CCOc2cccc3cccnc23)n1 +COC(=O)CNc1c(C)cccc1C(=O)N1CCC(O)CC1 +CC1CCc2onc(C(=O)N(C)Cc3ccccc3)c2C1 +O=C(Nc1cc(F)ccc1Cl)c1cccc(N2CCCC2=O)c1 +CCCCN(C)C(=O)c1cccn1-c1nnc(N2CCCC2)s1 +CN(CC1(CO)CCOCC1)C(=O)Nc1cccc(-c2ccco2)c1 +Nc1cccc2c1N(CCO)CC(c1ccccc1)O2 +Cc1nc2cc(C(=O)N3CCN(C(=O)C(C)(C)C)CC3)ccc2n1C +COc1ccccc1CNC(=O)C1Cc2ccccc2O1 +CCC(C)(NCC(=O)N1CCN(C(C)=O)CC1)c1nccs1 +Cc1noc(C)c1COc1cc2oc(=O)cc(C)c2cc1Cl +CCCn1cc(S(=O)(=O)N2CCc3ccc(OC)cc3CC2)cn1 +O=C(NCCNc1cccc(F)n1)c1ccccc1F +CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)Nc1ccccn1 +COc1ccc(NC(=O)n2nc(C)c3ccccc32)cc1OC +CC(C)(C)C(C#N)NC(=O)c1cccc(Oc2cnccn2)c1 +O=C(Nc1ccc(-n2cccc2)cc1)c1ccc2cc[nH]c2c1 +Cc1cc(C(=O)COC(=O)c2sccc2C2CC2)c(C)s1 +Cc1cc(C)cc(C(=O)N(C)Cc2cc(C)on2)c1 +O=C(c1nccn2ccnc12)N1CC2(CCCC2)c2c(F)cccc21 +Cc1cnc(-c2cccc(NC(=O)NCCc3ccnn3C)c2)o1 +CC(=O)Nc1ccc(C(=O)Nc2ccc(C)cc2NC(C)=O)cc1 +c1cc(-c2noc(-c3ccoc3)n2)cc(-c2ccn[nH]2)c1 +O=S(=O)(c1ccc2c(c1)CNCC2)N1CCCCC1 +CNc1nc(-c2cnn(-c3ccc(C)cc3C)c2C)cs1 +CN1CCc2c(sc3ncn4nc(-c5ccccc5O)nc4c23)C1 +O=C(NCc1ccccn1)Nc1cccc(-c2nnc3n2CCC3)c1 +O=C(CCc1cnccn1)NCC1COc2ccccc2C1 +COc1ccc(-c2ccc3ccccc3n2)nc1N +CCc1nc(C(C)NC(=O)Nc2cc(F)ccc2OC)cs1 +Cc1n[nH]c(C2CN(C(=O)c3cnc[nH]3)CCO2)n1 +CCC(C)n1ncc2cc(C(=O)NCC(C)C)c(N)nc21 +Cc1ccc(C(N)=O)cc1NC(=O)c1coc(-c2ccccc2)n1 +CC(C)Oc1ncnc2c1CCN(C(=O)c1ccsc1)CC2 +Cc1nc(COc2ccccc2C(=O)Nc2ccccc2)no1 +CC(Cc1ccccc1F)NC(=O)C(C)NC(N)=O +Cc1nc(-c2ccccc2NC(=O)N2CCOCC2C2CC2)no1 +Cc1ccc(NC2CCN(C)C2=O)cc1N1CCCS1(=O)=O +CCn1nnnc1SCC(=O)Nc1cccc(OC)c1 +CC(=O)N(C)c1cccc(NC(=O)Cc2ccc(F)c(F)c2)c1 +O=C(CSc1ccccc1)NCc1ccccn1 +Cc1ccc2[nH]c(=O)c(CN(CC(C)C)C(=O)c3ccncc3)cc2c1 +Cc1cc(C)n(CCCNC(=O)c2cc3ccccn3n2)n1 +O=C(Nc1ccc(Cn2cncn2)cc1)c1ccc2ccccc2c1 +Cc1cc(C)n2nc(SCC(=O)N(CCC#N)CCC#N)nc2n1 +Cc1noc(C2CCN(C(=O)c3ccc(C)s3)CC2)n1 +N#CCc1ccc(NC(=O)NCc2cc(Cl)ccn2)cc1 +COc1ccc(-n2ncc3cc(C#N)c(C#N)cc32)cc1 +CCN1CCN(C(=O)C2CC(=O)N(c3cc(C)cc(C)c3)C2)CC1 +Cc1cccc(N)c1S(=O)(=O)N1CCOCC1 +CC(=O)Nc1ccc(F)c(-c2nc(-c3ccc(C#N)cn3)no2)c1 +Cc1sc2ncnc(SCC(=O)n3ncc(C#N)c3N)c2c1C +CC(C)CN1CCOC(CNC(=O)N(C)Cc2cnn(C)c2)C1 +CCC(C)NC(=O)c1cc(-c2cccc(OC)c2)on1 +Cc1ccc(NC(=O)CNc2ccccc2C(=O)N(C)C)cc1 +Cc1noc2ncnc(N3CCC(C(=O)N4CCOCC4)CC3)c12 +CC1CCc2c(sc(NC(=O)c3ccco3)c2C#N)C1 +O=S(=O)(c1ccc2c(c1)CCO2)N(Cc1cccnc1)C1CC1 +COc1ccc(C(C)(C)CNC(=O)C2CC2c2ccco2)cc1OC +COc1ccccc1NC(=O)C(C)Oc1ccccc1N +CCCCN(CC)C(=O)c1cc(N)ccc1Cl +O=S(=O)(C1CC1)N1CCCn2cnc(COCC3CC3)c2C1 +CNC(=O)c1ccc(NC(=O)CCc2ccco2)cc1 +CC(Cc1cccs1)NC(=O)c1cnc(-c2ccncc2)nc1 +CC(=O)c1ccc(C#CCNC(=O)c2ccncc2)cc1 +CCOc1ccc(OCC(=O)Nc2ccccc2C(C)=O)cc1 +Cc1cc(S(=O)(=O)N2CCCCCC2)ccc1F +Cc1ccc(NC(=O)c2ccn(C)c(=O)c2)c(OCc2ccccc2)c1 +Cc1csc(NC(=O)c2cc(C)n(C(C)(C)C)n2)n1 +CCC(=O)N1CCN(c2ccc(NC(=O)c3ccco3)cn2)CC1 +CC(C)(CNC(=O)c1cc(F)ccc1O)c1ccncc1 +CC(C)CCNC(=O)NS(=O)(=O)c1ccc(Cl)cc1 +O=C(Nc1nc(-c2cccnc2)cs1)c1cccs1 +CC(NC(=O)NCC1CCCC1O)c1ccc(F)c(F)c1 +CCC(C(=O)NCCc1csc(-c2cnccn2)n1)n1cccn1 +O=C(NCc1ccc(OCC(F)(F)F)nc1)c1cccc(F)c1 +CC(NC(=O)Nc1ccc(Oc2cccnc2)nc1)C(C)(C)C +CN(CCCNC(=O)c1ccccc1-n1cnnn1)S(C)(=O)=O +CC(NC(=O)CCc1ccccc1OC(F)(F)F)c1ccncc1 +Cc1nc(C)n(C2CCCN(C(=O)c3ccc(C(C)(C)C)cc3)C2)n1 +CCc1nnc(Nc2cccc(C3CCCN3C(C)=O)n2)s1 +O=C(NCCCOCC1CCCO1)c1cc(F)cc(F)c1 +CC1(C)c2[nH]c3ccccc3c2CC2C(=O)N(CCCO)CC(=O)N21 +COC(=O)c1cc(OC)c(OC)cc1NC(=O)c1ccco1 +CS(=O)(=O)N1CCCC(CN2CCC(=O)Nc3ccccc32)C1 +Cc1[nH]c2ccnn2c(=O)c1CC(=O)N1CCc2cc(F)ccc2C1 +CC(C)(C)NS(=O)(=O)Cc1cccc(NC(=O)c2ccccn2)c1 +CC1(C)C(=O)C2(C(=O)Nc3nc4c(s3)CCCC4)CCC1C2 +Cc1cc(CC(=O)NCc2cnn(-c3ccc(Cl)cc3)c2)no1 +CCNc1nc(-c2ccccn2)nc2sccc12 +CC(=O)NCCNC(=O)Nc1ccc(C(C)=O)c(C)c1 +CCN(C)S(=O)(=O)N(Cc1ccccc1)CC(F)F +Cc1ccnn1-c1ccccc1NC(=O)NC1CCC(O)CC1 +Cc1ccc(S(=O)(=O)Nc2ccc(CC(=O)N(C)C)cc2)cc1 +COc1ccc(C2NC(=O)c3oc4ccc(F)cc4c(=O)c32)cc1 +Cc1ccc(C(=O)NCC(=O)NC2CCSc3ccccc32)s1 +CCc1nc(C)c(C(=O)N(C)Cc2cc(-c3ccccc3)on2)o1 +CN(C)C(=O)c1ccnc(S(N)(=O)=O)c1OC1CC1 +COc1ccccc1CNC(=O)c1cn[nH]c1-c1ccccc1 +Cc1cc(C(=O)N2CCCC2)ccc1NC(=O)NCc1ccncc1 +Nc1cc(C(O)CNc2ccc(F)cc2)ccc1Cl +CC(C#N)CNC(=O)c1c(F)c(F)c(F)c(F)c1F +Cc1nc(-c2ccc(F)cc2)nc(N2CCC(=O)CC2)c1C +Cc1cc(NS(=O)(=O)c2cccc(Cl)c2)ccc1N +O=C(Cn1nc2ccccn2c1=O)Nc1ncc(Cl)cc1Cl +CC(C)Oc1cccnc1C(=O)NCCc1nc2ccccc2n1C +CCC(=O)Nc1ccc(C(=O)COc2ncnc3ccccc23)cc1 +Fc1cc(-c2nc(-c3ccncc3)no2)ccc1N1CCOCC1 +CN(C)C(=O)C1CCN(C(=O)c2csc(-c3cccs3)n2)CC1 +COc1ccc(F)cc1NC(=O)N(C)CCNC(=O)C(C)C +CC(OCc1ccccc1)C(=O)Nc1ccc(F)cc1N +CCOc1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 +Cn1ncc2c(=O)[nH]c(CN3CCOC(c4ccc(F)cc4)C3)nc21 +Cc1cccc(C(=O)NCC(=O)NCc2ccc(Cl)cc2)c1 +C=CCN(Cc1cccc(C#N)c1)S(=O)(=O)c1cnn(C)c1 +COCCn1ccc(NC(=O)C(C(C)C)N2CC(C)OC(C)C2)n1 +CC(C)(O)CN1CCN(C(=O)c2cc(Cl)ccc2Cl)CC1 +Cc1cccc(C(=O)Nc2ncccc2Br)c1 +CC(=O)OC(c1ccccc1)c1nc2ccccc2[nH]1 +Cc1ccccc1CC(=O)Nc1cccc(-c2nncn2C)c1 +O=C(NCCN1CCNC1=O)Nc1ccc(OC(F)(F)F)cc1 +Cc1ccc(-c2n[nH]c(C)c2NC(=O)NC(C)C)c(C)c1 +O=C(c1ccccc1-n1cccc1)N1CCOC(c2ccccc2)C1 +CC(C)C(=O)N(C)Cc1ccc(C(=O)N2CCOCC2C2CC2)cc1 +COC(=O)c1ccc2c(c1)CCN2C(=O)C1CC1C +CC(C)OC(=O)C(C)CNS(=O)(=O)N1CCCC1 +Cn1nc(CNC(=O)c2cccn(C)c2=O)cc1-c1cccs1 +O=C(C1CCOCC1)N1CCCC1c1cccc(F)c1 +COCCCNC(=O)c1cccc(Br)c1 +COCc1cc(C(=O)N(C)C(C)c2ccc(C)cc2)ccc1F +COC(=O)CNC(=O)NCCn1nnc2cc(C(=O)N(C)C)ccc21 +Cn1nccc1CN1CCN(C2CCN(c3ccccc3)C2=O)CC1 +Cc1ccc(Br)cc1NC(=O)CSc1ccncc1 +CN1CCN(C(=O)c2cnn(C)c2-n2cccc2)CC1 +O=C(NCc1ccco1)C1C=CCN1C(=O)NCc1ccccc1 +CCC(C)CNS(=O)(=O)Cc1ccccc1C#N +O=C(Cn1ccc2sccc2c1=O)NCCC1=CCCCC1 +NC(=O)c1csc(NC(=O)c2cccc(OCC(F)F)n2)n1 +CCOc1ccc(C(=O)Nc2ccc3c(c2)OCCCO3)cc1 +O=C1CC(C(=O)N2CC3CC=CCC3C2)CN1Cc1ccccn1 +COc1c(F)ccc2c1CCNC2CC(C)(C)C +COc1cc(N)c(C(=O)N2CCNC(=O)C2)cc1OC +O=C(c1cccs1)N1CCC2(CC(=O)N(c3cncnc3)C2)C1 +Cc1[nH]ccc1C(=O)Nc1ccnn1Cc1cnn(-c2ccccc2)c1 +CC1(C)CN(C(=O)CNC(=O)Cc2cccc3ccccc23)CCO1 +CC(NS(C)(=O)=O)C(=O)Nc1ccccc1N1CCCC1 +CC(=O)N1CCc2c(c(-c3ccc(N)cc3)nn2CC(N)=O)C1 +NC(=O)C(CCC(F)(F)F)NS(=O)(=O)c1ccc(Cl)cc1 +CCCOc1cccc(C(O)CCN2CCOCC2)c1 +CC(=O)c1ccc(S(C)(=O)=O)c(N2CCCC(c3cn[nH]c3)C2)c1 +CCC(C)C(=O)Nc1c(C)cc(Br)cc1C +Nc1ccc(C(O)C(CO)NC(=O)COc2ccccc2)cc1 +CCn1ncc(-c2ccc(C)cc2C)c(CC#N)c1=O +Cc1nc2ccc(N)cc2c(=O)n1-c1ccc(F)cc1 +CC1COCCN1CC(O)c1ccccc1Cl +CC(C)CCOc1ccc(C(=O)N2CCCC2)cc1 +O=C(c1ccnnc1)N1CCC2(CC(Oc3ncccc3F)CO2)C1 +CS(=O)(=O)NCC1(Sc2ccccc2)CC1 +COCCSc1nnc(NC(=O)Cc2ccc(F)cc2)s1 +Cc1cc(NC(=O)Cc2csc(-c3ccccc3)n2)no1 +CCc1nnc(SCC(=O)Nc2ccc(C)cc2)n1CC +COCCNC(=O)c1[nH]c(-c2ccccc2)c2c1CCC2 +Cc1nc(C)c(C(=O)NCC(O)Cc2ccccc2)o1 +CC(C)(CC1CCOCC1)C(=O)Nc1ccc2c(c1)COC2 +CCN(C)C(C(=O)Nc1ccc2c(c1)CCC(=O)N2)c1ccccc1 +Cc1cc(C)cc(C(=O)NCC(=O)N2CCc3cc(F)ccc3C2)c1 +Cc1ccc(-c2csc3ncc(C(=O)NCC(C)C)c(=O)n23)cc1 +Nc1nc(N2CCC3(CC2)CNC(=O)C3)c2nc[nH]c2n1 +CC(C)Cc1cc(C(=O)N2CCc3cc(C(N)=O)n(C)c3C2)on1 +O=C(c1ccc(CN2CCOCC2)cc1)N1CCc2ccccc21 +CC(C)COCC(O)CNC(=O)Nc1cccc(Cl)c1 +C=CCCC(=O)Nc1cc(S(=O)(=O)NC(C)(C)C)c(F)cc1F +O=C(c1ccccc1)C1CCCN(c2nncc(-c3ccccc3)n2)C1 +O=C(c1ccccn1)N1CCC(c2nnc(-c3ccccc3)o2)C1 +Cc1cc(NC(=O)C(C)n2cc(Cl)c(C)n2)no1 +CCCCNC(=O)Cc1ccc(S(=O)(=O)N2CCOCC2)s1 +O=C(NCC(O)c1ccc(Br)cc1)C1CC1 +NC(=O)CSc1nnc2nc3[nH]c4ccccc4c3nn12 +Cc1csc(SC(C)C(=O)N(C)C2(C#N)CCC(C)CC2)n1 +COc1ccc(CC(=O)N(C(C)C)C2CCC2)cc1 +CCS(=O)c1ccccc1C(=O)N1CCc2cc(F)ccc2C1 +Cc1ccc2c(n1)sc1c(=O)n(-c3ccccc3F)nnc12 +N#Cc1ccccc1S(=O)(=O)N(CCC(N)=O)c1ccccc1 +CC(=O)Nc1ccc(C)cc1NC(=O)c1cc(N(C)C)ccn1 +COc1ccc(C(C)N(C)C(=O)NCCNC(=O)C2CC2)cc1 +Cc1nn(C)c(C)c1CNC(=O)c1ccccc1-n1cnnn1 +Cc1cc(C)n(CC2CN(C(C)c3nnc(C)o3)CCO2)n1 +COc1ccc(-c2c(C(C)C)nc3nc(C)nn3c2N)cc1 +CC(COCC(F)(F)F)NC(=O)Nc1cccc(-n2cccn2)c1 +CC1(NC(=O)c2ccc(S(N)(=O)=O)o2)CCCC1 +Cc1c(S(C)(=O)=O)c(N)n(Cc2ccccc2)c1C +CC(C)(CC(=O)Nc1ccccn1)c1ccccc1 +CC(C)(C)OC(=O)N1CCC2(CC1)CNc1ccc(F)cc1N2 +CCOCCC(=O)Nc1nnc(C23CC4CC(CC(C4)C2)C3)s1 +CCOc1ccc(Cl)cc1S(=O)(=O)NC(C)COC +CC(O)c1nc2ccc(F)cc2n1Cc1cccnc1 +CC(=O)C(C)OC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 +CN(CCc1ccccn1)C(=O)Cn1c(=O)[nH]c2ccccc2c1=O +CC1CCC(C)(NC(=O)CNS(=O)(=O)c2cn(C)cn2)CC1 +CCc1ncc(C(=O)N(CCOC)Cc2cnn(C)c2)cn1 +CCCn1nc(C(=O)N(Cc2cccnc2)C2CC2)ccc1=O +Cc1cc(NC2CCN(c3ccc(F)cc3)CC2)n2nc(C)cc2n1 +COc1ccc(OC)c(CNC(=O)c2ccc(O)c(Cl)c2)c1 +COCCNC(=O)CCNc1cncc(Br)c1 +Cc1cc(C)n(-c2cccc(NC(=O)c3ccc(F)cc3)c2)n1 +C#Cc1cccc(N(C(=O)CCC(=O)N(CC)CC)C(C)C)c1 +CNC(=O)c1cccc(NCC(=O)NC2CCCCC2)c1 +O=C(Nc1nc2c(s1)CCCC2)c1coc2ccccc2c1=O +CCNC(=O)c1cccc(CNC(=O)c2scnc2C2CC2)c1 +CC1CCC(NC(=O)Nc2ccnc(C(=O)N(C)C)c2)C(C)C1 +O=C(NCc1nnnn1-c1ccc(F)c(F)c1)c1ccccc1 +COCCOCC(=O)Nc1cccnc1-n1cccn1 +N#CCCN(C(=O)c1ccc(CNC(N)=O)cc1)c1ccccc1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)C(=O)NCCNC(C)=O +O=C(CNC(=O)NCc1ccccc1)NCc1ccccc1 +Cc1ccc(N)cc1NC(=O)CCOC(C)c1ccccc1 +N#CCc1c(Br)cccc1Br +O=C(NC1C(O)C(O)CC1C1CCCCC1)C1CC1 +O=C(Nc1nnc(SCc2ccc(F)cc2F)s1)C1CCC1 +Cc1csc(CCNc2ccc(N)cc2F)n1 +CCn1nc(C)c(CN(CC2CC2)C(=O)c2cccnc2)c1C +Cc1ccc(-c2cn3c(nc4cc(N)ccc43)[nH]2)cc1C +Cc1ccc(C(=O)N(C)Cc2nc3ccccc3s2)s1 +COc1cccc(C(=O)NCc2noc(C(C)(C)C)n2)c1F +O=C(c1cnccn1)N1CCN(c2ccc(C(F)(F)F)cn2)CC1 +CCCS(=O)(=O)N1CCCN(C(=O)c2cccc(F)c2)CC1 +O=C(c1ccc(F)cc1)N1CCC2(CCCC2)CC1 +COc1ccc(C2CN(c3ccc(C)nn3)CC2NC(C)=O)cc1 +O=C(CCNC(=O)c1ccco1)OCc1ccccc1F +COC(=O)c1ccc(OCC(=O)c2c[nH]c3ccccc23)cc1 +COc1cccc(C(=O)N(C)C(C#N)c2cccc(C)c2)c1 +O=C(NCc1ccc2c(c1)OCO2)NC(c1ccccc1)C1CC1 +CCc1nc(CNC(=O)NCC(C)Nc2ccccc2)cs1 +COc1c(Br)cccc1CCNC(=O)c1cccnc1 +CN1C(=O)Cc2cc(NS(=O)(=O)c3ccccc3F)ccc21 +Cc1cccc(-c2nc3cc4c(cc3n2CC#N)OCCO4)c1 +Cc1noc(CSc2nnc3n2CCCCC3)n1 +CCC1C(=O)CN1S(=O)(=O)c1ccc(C)cc1 +CC(Sc1ccccc1Cl)C(=O)NCc1cscn1 +N#CC1c2ccccc2C=CN1C(=O)c1cccs1 +O=C(NCc1cccnc1)c1ccc(=O)n(-c2ccccc2)n1 +N#Cc1ccc(N2CCC(OC(=O)c3n[nH]c4ccccc34)C2=O)cc1 +c1ccc(-n2cnnc2SCCN2CCOCC2)cc1 +COc1ccc(OCC(=O)Nc2ccc(-n3ccnc3)nc2)cc1 +Cn1ncnc1SCc1ncc(-c2ccccc2)o1 +Cc1nnsc1CN(C)c1nc(C2CCCC2)nc2c1cnn2C +CC(=O)c1ccc(OC(=O)Cc2csc(-c3ccccn3)n2)cc1 +N#Cc1cccnc1N1CCN(C(=O)C2CC=CCC2)CC1 +CCN(CCC(=O)OC)C(=O)c1ccc(=O)[nH]c1 +Cc1cccc(OCC(=O)Nc2cnn(CC(F)(F)F)c2)c1 +CC(C)c1ccc(NC(=O)CCCNC(=O)c2ccco2)cc1 +COc1ccc(NC(=O)CC(C#N)c2ccco2)cc1 +CCOC(=O)CN(C(=O)Cc1cc(=O)[nH]c(=O)[nH]1)C(C)C +COc1ccc(CNC(=O)Cc2ccc(OC(F)(F)F)cc2)cn1 +Cc1csc(N2CCN(C(=O)c3c(C)noc3C)CC2)n1 +Cc1nc(-c2cccc(OCC(=O)Nc3cc(F)ccc3F)c2)no1 +CCOC(=O)c1ccsc1NC(=O)c1ccn(CC)n1 +COc1ccc(-n2cc(CNC(=O)c3ccc(C)[nH]c3=O)nn2)cc1 +COc1cccc(CNC(=O)c2ccc(F)cc2)c1OC +Cc1cnc(NC(=O)c2cc(S(C)(=O)=O)ccc2Cl)s1 +CCOc1ccc2c(c1)cc(C(=O)NC(C)C)n2C +C=CCNC(=O)CC(C#N)c1cc(F)ccc1OC +Cc1ccc(S(=O)(=O)Oc2ccc(S(C)(=O)=O)cc2)cc1 +COc1ccc(NS(=O)(=O)c2cccc(C(C)=O)c2)cc1C +COC(=O)CCCNC(=O)c1ccc2ccccc2c1 +O=C(CSc1ccccc1F)Nc1ccc(F)cc1 +O=C(NCc1ccccc1)c1ccc(S(=O)(=O)C(F)F)cc1 +CCCN(C)C(=O)C1CN(Cc2ccccc2)CCO1 +O=C(Nc1ccc(-c2csnn2)cc1)C1CC=CCC1 +CCC(C)OC(=O)CC1C(=O)NCCN1C(=O)c1ccc(F)cc1 +COC(=O)CN1C(=O)C(C)Oc2ccc(CO)cc21 +CC1CCc2c(sc(NC(=O)c3cccnc3)c2C(N)=O)C1 +COCC(=O)N(C)CC(=O)Nc1c(F)cccc1Br +COCCNC(=O)Nc1ccc(NC(=O)c2ccco2)c(Cl)c1 +O=c1n(Cc2ccc(C(F)(F)F)cc2)nc2ncccn12 +O=C(c1cc(-c2ccccc2F)n[nH]1)N1CCCC(O)(CO)CC1 +COc1ccc(F)cc1NC(=O)NC(C(N)=O)C(C)(C)C +CCOC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1C +COCc1nc(C2CCN(c3cc(C)ncn3)CC2)no1 +CC(C)c1n[nH]c(N)c1-c1nc2ccccc2s1 +CN(CC(=O)N1CCC(Cc2ccc(F)cc2)CC1)c1cnccn1 +Cc1occc1CN(C)C(=O)NC1CCSc2c(F)cccc21 +O=C(NCc1ccncc1)C1(c2cccs2)CCCC1 +NC(=O)C1CCCN1C(=O)Cc1cccc2cccnc12 +O=C(CCc1ccccc1)N1CC2(CCN(C(=O)c3ccncc3)C2)C1 +COc1ncccc1C(=O)Oc1ccc(NC(=O)C2CC2)cc1 +CC(C)COCCCNC(=O)Nc1cnn(C)c1 +Cc1ccc2oc(C(=O)N3CCNC(=O)C3)cc2c1 +CC(C)c1cc(C(=O)NCCOc2cccnc2)nn1C(C)(C)C +Nc1nonc1-c1nc(-c2ccc(O)cc2)cs1 +Cc1cc(CNC(=O)C2CCCCN2C(=O)OC(C)(C)C)on1 +Cc1ccccc1-n1ncc(C(=O)OCCNc2ncccn2)c1C +CN(C)S(=O)(=O)n1c2ccccc2c2nc3ccccc3nc21 +CCOC(=O)N1CCC(NC(=O)Nc2ccc3ccccc3c2)CC1 +CC(CO)C(C)NC(=O)NCCC1Cc2ccccc2C1 +CSc1n[nH]c2ncnc(NCCCn3cccn3)c12 +COc1cc2c(cc1OC)CN(C(=O)C(C)n1nc(C)cc1C)CC2 +COCc1cn(CC2CCCN(c3ncnc4[nH]cnc34)C2)nn1 +COc1cc(CSc2ncn[nH]2)ccc1SC +CC(C)(C)n1nc2c(c1-n1cccc1)CN(C(=O)c1ccccc1)C2 +CCCn1nnnc1CSc1nc(C)nc2sc3c(c12)CCC3 +CCOc1ccccc1CC1Oc2ccc(O)cc2N(C)C1=O +CCc1cc(NCc2ccccc2N2CCOCC2)n2ncnc2n1 +C=CCNC(=O)Nc1ccc(NC(=O)c2scnc2C2CC2)cc1 +OCC1NCCc2ccc(OC(F)F)c(OC(F)F)c21 +CCc1nc(COC(=O)CCc2c(C)nn(C)c2C)cs1 +NC(=O)c1cnc2scc(-c3ccccc3)n2c1=O +O=C(CC12COCC1CN(c1ncc(F)cn1)C2)N1CCOCC1 +CN(C)C(=O)C1CC2CCN(S(C)(=O)=O)CC2O1 +COCCCNC(=O)CC(C#N)c1cccc(Cl)c1 +COc1ccccc1C1CCCN1C(=O)c1cnn2c1CCCC2 +Cn1nnnc1SCC1NCCc2c1ccc(F)c2O +N#Cc1ccsc1NC(=O)CSc1ccc(F)c(F)c1 +O=C(NCC(=O)N1CCCCC1)c1cc2cnsc2s1 +CCC(NS(=O)(=O)c1c(C)nn(C)c1C)c1cccs1 +CCOC(=O)CNC(=O)N1CCOC(Cc2ccc(OC)cc2)C1 +O=C(Cn1cnc2ccccc2c1=O)NC1CCc2c(F)cccc21 +CC(C)OCCCNC(=O)NC1CCC(O)CC1 +Cc1ccccc1NC(=O)C1CCCN(C(=O)c2ccco2)C1 +O=C(Nc1ccccc1F)C1CC1c1ccccc1 +Cn1nc2n(c1=O)CCN(C(=O)Nc1ccc(F)cc1Cl)C2 +CS(=O)(=O)NCCNC(=O)CCc1cccc(Cl)c1 +CC(c1nc(C2CC2)no1)N1CCN(c2ccc(O)cc2)CC1 +O=C(COc1ccccn1)Nc1ccc(Cl)cc1 +COc1ccc(C2(Cc3cccc(F)c3)NC(N)=NC2=O)cc1 +COc1ccnc(NC(=O)c2sccc2Br)c1 +CC1(C)C2CCC1(C)C(NS(=O)(=O)N1CCOCC1)C2 +CCc1ncc(C(=O)NC2CCCCC2C)c(N)n1 +COc1cccc(OCCc2nc(C(C)C)c(CO)s2)c1 +COc1ccc2[nH]cc(CC(=O)NCC(C)(C)c3ccncc3)c2c1 +Cc1cccnc1NC(=O)CCCOc1cccc(F)c1 +Cc1ccc(NC(=O)c2onc(-c3ccccc3)c2N)cc1C +CC(CC(=O)NCc1ccc2c(c1)OCO2)n1cccn1 +C1CC(c2noc(C3CC3)n2)N(Cc2nc(C3CC3)no2)C1 +CC(C)c1ccc(C(N)C(=O)NCC(O)CO)cc1 +CC(=O)Nc1ccc(S(=O)(=O)NCc2c(C)nn(C)c2C)cc1 +Cc1cc(-c2nnn(CCNC(=O)OCC(F)(F)F)n2)ccc1F +CC(NC(=O)COC1CCCCC1)C(O)c1ccc(F)cc1 +O=C(Nc1nnc2ccccn12)c1cccc(Cl)c1 +C#CCNC(=O)c1cc(-c2ccccc2)nc2ccccc12 +COc1cccc(OC)c1COC(=O)C(C)c1cccs1 +CC(=O)c1sc2nsc(S(C)(=O)=O)c2c1N +O=C(c1cccc2ncccc12)N(Cc1ccccc1F)C1CC1 +COC(=O)c1ccsc1NC(=O)c1ccc(S(C)(=O)=O)cc1 +Cc1nc(C2CCN(S(=O)(=O)c3cccnc3)CC2)n[nH]1 +CCCc1sc(C(=O)N2CCc3[nH]ncc3C2)cc1CC +O=c1cc[nH]c(C2NCCc3cc(F)c(O)cc32)c1 +Cc1occc1C(=O)Nc1ccc(NC(=O)c2cccs2)cc1 +CN(C(=O)C1CCCN1C(=O)Cc1cccs1)c1ccccc1 +COc1cccc(C(O)CCC(=O)NC2CCCCC2)c1 +CC1=CC(c2ccccc2)c2c([nH]c(=O)[nH]c2=O)O1 +O=C1CN(C(=O)Cn2c(-c3cccnc3)noc2=O)CCN1 +O=C(c1ccccc1-c1ccccc1)N1CCc2c(nc[nH]c2=O)C1 +CCOc1c(Cl)cc(CN2CCOC(C)C2C)cc1OC +CC(C)n1cnnc1SCC(=O)Nc1nc2c(s1)CCCC2 +CNC(=O)NC(C)(C)C(=O)NCc1ccccc1OC +CC1(C)CN(c2ccc(OC(F)(F)F)cc2)C1=O +CC(C)(C)C(=O)NCCC(=O)Nc1ccc(F)cc1 +CCOCc1cncc2c1CCN(C(=O)Cc1ccsc1)C2 +CCCS(=O)(=O)NCc1ccc(-n2cncn2)cc1 +CC1c2ccsc2CCN1c1cc(C#N)ccn1 +CCC(=O)N1CCCC(C(=O)NCCc2cc(C)cc(C)c2)C1 +Cc1cc(C)c(NC(=O)C(C)n2nnc(C#N)c2C)c(C)c1 +O=C(Nc1cccs1)OCC(Cl)(Cl)Cl +OCC#Cc1ccc(COCc2cccs2)cc1 +CC(=O)C(C)n1c(C(C)NC(=O)c2cccs2)nc2ccccc21 +CC1(C)CC(CC(=O)Nc2nc(-c3ccccc3)cs2)C(=O)O1 +CC1(COC(=O)C2COc3ccc(F)cc3C2)COC1 +CCOc1ccc(-c2nc(C(=O)NCC3CCCO3)cs2)cc1 +COc1cc(F)c2c(c1)C(Cc1cccc(O)c1)NCC2 +Cc1ccc(S(=O)(=O)N2CCCOCC2)c(N)c1 +CCNC(=O)CN1CCN(C(=O)CCC2CCCC2)CC1 +CN(C)C(=O)C(NC(=O)CC(C)(C)C)c1ccccc1 +CNc1cncc(C2CCCN2S(=O)(=O)C2CCCCC2)n1 +Cc1cc(=O)c(O)c(CN(CCO)CCO)n1C(C)C +Cc1nn2c(c1-c1ccccc1)NC(=O)CC2c1ccccc1 +Cc1cc(C)nc(SCC(=O)NC(C)(CC(C)C)C(N)=O)n1 +CC(NC(=O)CSc1nnnn1C1CCCC1)c1ccco1 +Cn1ccc(C(=O)Nc2ccc(Cl)cc2Cl)cc1=O +CCC1C(=O)NCCN1Cc1cn(C)nc1-c1cccnc1 +O=C(Nc1nncs1)N1CCCCC1Cc1ccccc1 +Cc1ccc(C(=O)CCC(=O)NC(C)Cc2ccccc2F)s1 +CC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccc(F)c(F)c2)cc1 +COc1ccc(NC(=O)CNC(=O)OC(C)(C)C)cn1 +CC(C)OC(=O)CCCc1ncc(-c2ccccc2)o1 +Cc1noc(CCC(=O)NCc2ccc(OC(C)C)cc2)n1 +CN(C(=O)c1ccc(C(N)=O)cc1)C1CCc2ccccc21 +COc1ccc(-c2cnc(NCc3ccc(F)cc3)n2C)cc1 +COC(=O)C1=C(N)OC2=CC(C)=NC(=O)C2C1c1ccccc1F +CCc1nnsc1C(=O)NC(c1nccn1C)C1CC1 +CCN(CC)C(=O)CN(C)C(=O)Cc1ccccc1O +Cc1cccc(NC(=O)C(C)NC(=O)c2cccs2)n1 +O=C(Cc1c(F)cccc1Cl)Nc1cccc(CO)c1 +CCC(C)NC(=O)CC(C#N)c1c(C)cc(C)cc1C +CCN(CC1CC1)C(=O)CNC(=O)c1ccc(Cl)cc1Cl +COCCCn1c(SCC(=O)N2CCCCC2C)n[nH]c1=O +COc1cc(C#N)ccc1OC(=O)c1cccs1 +CN(Cc1ccccc1)C(=O)COC(=O)c1ccccc1O +Cc1cc(C)cc(-c2nnc(SC3CC(C)OC3=O)o2)c1 +Cc1ccc(-c2nnc(CC(=O)NC3CC3)o2)cc1 +Cc1ccc(OCC(=O)NC(C)c2c(C)noc2C)cc1C +Clc1ccc(N2CCN(Cc3cnc4cnccn34)CC2)cc1 +CC1CC(C)CN(C(=O)NCc2cccc(Cn3ccnc3)c2)C1 +CCOC(=O)c1ccn(-c2cccc(NC(=O)N3CCCC3)c2)n1 +Cc1nnc2n1CCN(C(=O)c1cccc(-n3c(C)c[nH]c3=O)c1)C2 +Cc1noc(NCc2ccc3cc(O)ccc3c2)c1C +O=C(OCC(=O)N1CCN(c2ncccn2)CC1)C1CC2CCC1C2 +COc1ccc(CNC(=O)CSc2cc(C)ccc2C)cc1OC +O=C(Cn1nc(-c2ccccc2Cl)ccc1=O)N1CCCCCC1 +COc1cc(OC)c(NC(=O)C2(c3cccc(F)c3)CC2)cc1F +N#Cc1ccc(N2CCN(Cc3cc(C(N)=O)cs3)CC2)c(F)c1 +COCCCNC(=O)c1cc2c(=O)[nH]c3ccccc3c2n1C +Cc1nc2c(c(=O)n1C)CCN(C1=NC=NC3=NC=NC31)CC2 +Cc1ccc(NC(=O)c2nc3ncccn3n2)c(C)c1 +Cc1onc(-c2ccccn2)c1C(=O)NC(C)c1ccccc1 +Cn1nccc1CNC(=O)NCCOc1ccccc1 +Cc1nc[nH]c1C(=O)N(CCc1ccccc1)Cc1ccccn1 +CC(=O)NCCNC(=O)c1cc(C(C)C)nc2c1cnn2C(C)C +CC(=O)c1cnc2nc(SCCC(C)C)nn2c1C +COc1ccc(C)c2sc(N3CCOCC3)nc12 +O=C(Nc1cccc2cn[nH]c12)c1ccc(F)cc1 +CC(C)N(C(=O)COc1ccccc1C(N)=O)C1CCCC1 +COc1cccc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)c1 +CC(NC(=O)N1CCOCC1C1CC1)c1cnn(C)c1 +Cn1cnc(CNC(=O)NC(C)(C)Cc2ccccc2Cl)n1 +COc1ccc(S(=O)(=O)NCc2ccco2)c2cccnc12 +CC(=O)N1CC(C(=O)Nc2ccc(C)c(C)c2)Oc2ccccc21 +CCc1cccc(C)c1NC(=O)Cn1cnc2ccccc21 +CCC1CCCCN1C(=O)CSc1nnc(C)s1 +N#Cc1cccc(C(=O)N2CCC3(CC(=O)c4ccccc4O3)C2)c1 +CCCCN(CC(N)=O)S(=O)(=O)c1c[nH]nc1N +Fc1cc2c(c(F)c1F)C(Cn1cnnn1)NCC2 +CC(CC(O)c1ccco1)Nc1ccc(Cl)cn1 +O=C(NCCN1CCCCCC1=O)c1cc[nH]n1 +CCCNC(=O)c1ccc(-n2ncc(C(=O)OC)c2N)cc1 +CCN(CC)C(=O)CNC(=O)c1cccc(Br)c1 +Cc1csc(N2CCCN(Cc3csc(C)n3)CC2)n1 +CC(=O)N(C)Cc1cccc(NC(=O)C2(c3ccccc3)CC2)c1 +O=C(Cc1ccccc1F)N1CCN(Cc2cc(F)cc(F)c2)CC1 +CCN(CC)C(=O)NCCc1nnc(-c2ccccc2)o1 +CC(C)N(C)C(=O)NCc1ccc(CN2CCCC2=O)cc1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)OCc2ccoc2)c1 +O=C(Nc1cc(Cl)c(Cl)cn1)c1cc(-n2cccn2)ccn1 +O=C(CCNc1ncccn1)NC1CCCNC1=O +O=C(CCCc1nc(C2CC2)no1)N1CCc2cc(F)ccc2C1 +N#Cc1ccc(N2CCC(OCc3ccccc3)CC2)nc1 +Nc1cccc(CC(=O)Nc2cc(C(F)(F)F)ccc2Cl)c1 +Cc1ccsc1CN1CCC2(CC(OCC(=O)N(C)C)CO2)C1 +Cc1nc2ccc(NC(=O)N(C)Cc3ccccn3)cc2s1 +O=C(Nc1ccccc1NCCc1ccccn1)c1cc(Cl)c[nH]1 +COc1ccc(OC)c(CCCNc2ncnc3nn(C)cc23)c1 +Cc1nc(C(=O)N2CCCC2c2cccc(Cc3ccccc3)n2)co1 +COc1ccccc1C(CNC(=O)C1CCC1)NC(=O)C1CCC1 +Nc1cnc(NC2CCCC2)c(Br)c1 +Cc1cc(NC(=O)C2CCCO2)c2ncccc2c1 +COc1cc(C(=O)NCCc2ccccc2)nc(OC)n1 +Cc1nnc2n1CCN(CC(=O)Nc1ccc(Cl)cn1)C2 +Cc1cccc(C(=O)OCCn2nc3ccccn3c2=O)c1 +CCOc1ccccc1OC(=O)CCc1ccco1 +COCCNC(=O)CCNC(=O)Nc1ccccc1F +O=C(CNC(=O)c1ccc2c(c1)OCO2)Nc1nc2ccccc2[nH]1 +CC#CCSc1nc2ccccc2n1CCOC +O=C(NCc1csc(C2CC2)n1)C1CC1c1cccc(F)c1 +CC(CC#N)N(C)S(=O)(=O)c1ccccc1Br +CCNC(=O)C(C)NC(=O)NCc1cnn(C)c1 +Nc1ccc(-c2nc(Cc3cccs3)n[nH]2)cc1 +CCn1nccc1C(=O)Nc1sccc1C(=O)OC +CCS(=O)(=O)N1CCC(n2nc(-c3ccoc3C)oc2=O)CC1 +CC1CCCC(C)N1C(=O)Cn1cnc2sc3c(c2c1=O)CCC3 +C=CCC(=O)N1CCCC(N2CCN(c3ccccc3C)CC2)C1 +CC(NC(=O)CNC(=O)c1ccc(F)cc1F)c1ccccc1 +COc1ccc(C(C)CCNC(=O)c2nccn2C)cc1 +CCOC(=O)C1CCN(C(=O)c2ccn(C3CCCC3)n2)CC1 +COc1ccc(NC(=O)CNc2c(F)cccc2F)cc1OC +CC(C)C(=O)Nc1nc(CC(=O)OC2CCCCC2)cs1 +CC(C)COc1cccc(C(=O)Nc2nc[nH]n2)c1 +O=C(NCC(=O)N1CCOCC1C1CC1)c1c(F)cccc1Cl +CC(C)(C)C(=O)CNC(=O)c1cc(Cl)ccc1Cl +O=C(CCC1CCCCC1)N1CC(c2nc(-c3ccco3)no2)C1 +CCN1C(=O)C(C)(C)c2cc(NC(=O)C3CCC3)ccc21 +CCOC(=O)CCCNC(=O)Nc1cnccc1C +Cn1c(C(=O)NCCc2cccs2)cc2ccc(F)cc21 +Cc1ccc(-c2noc(N3CCN(C(=O)C4CCCO4)CC3)n2)cc1 +CC(C)NS(=O)(=O)c1ccc(C(=O)NC2CC2)cc1 +Cc1ccncc1NC(=O)NCC(O)c1cccc(OC(F)F)c1 +O=C(Cn1ncnc1-c1ccccc1Cl)NCC1CCC1 +CN(C)C(=O)C1CCCN1C(=O)Cn1ccccc1=O +CCOCC(=O)Nc1ccc2c(c1)OCC(C)(C)C(=O)N2CC +CC(CNC(=O)COCc1nc2ccccc2[nH]1)N1CCOCC1 +Nc1cc(F)c(OCc2ccccc2Cl)c(F)c1 +Cc1nc(S(=O)(=O)NCCCN2CCOCC2)cn1C +CC(C)(CO)n1c(-c2ccncc2)nc2ccccc21 +Cc1ccc(-n2ncc3c(=O)n(N)cnc32)cc1C +CC(=O)Nc1ccc(NC(=O)CN2CC(C)c3ccccc32)cc1 +CCCOCC(=O)NC(C)c1ccc(NC(N)=O)cc1 +COc1ccccc1OC(C)C(=O)NC1CCCCC1 +COc1cccc(C(=O)NCC2CCOC2C(C)C)c1F +CC1CN(CC(=O)NCCC(C)(C)C)C(C)CO1 +CC(C)CC(=O)NC(C(=O)Nc1ccc2c(c1)COC2)C(C)C +COC(=O)C(C)NC(=O)C1CN(C(C)=O)CCN1C(=O)NC(C)C +CC(C)c1noc(C2CCCN2C(=O)c2cnn3ccccc23)n1 +Cn1cc(C(=O)CSc2nnnn2Cc2cccs2)cn1 +O=C(NCc1csc(=O)[nH]1)c1ccc(OCc2cscn2)cc1 +N#Cc1ccc(OCc2nc(-c3cccs3)no2)cc1 +c1ccc(OCC2CC2)c(CN2CCOC3(CCC3)C2)c1 +O=C(c1ccc(Br)cc1)N1CCCCC1C1OCCO1 +COc1ccccc1Oc1c(C)oc2cc(O)ccc2c1=O +CCOCCNC(=O)N(C)Cc1c(C)noc1C +Nc1c(-n2cnc3ccccc32)ccc2scnc12 +c1cncc(CNCCc2cccc3ccccc23)c1 +CCn1c(=NC(=O)c2ccnn2C)sc2cccc(OC)c21 +COc1cc(Br)ccc1CCCNC(=O)C(C)O +Cn1cc(CCNCc2cn(C)nc2-c2ccncc2)cn1 +CC1CCCCN1C(=O)CCNC(=O)NC1CC=CC1 +Cn1nnnc1SCCNC(=O)Nc1ccc2c(c1)oc(=O)n2C +C#Cc1cccc(NC(=O)C2OCCc3ccccc32)c1 +CC(OC1CCCCC1)C(=O)Nc1cccc(C#N)c1 +COc1ccc(OC)c(NC(=O)Cc2ccc(F)cc2)c1 +CCNC(=O)c1cccc2c1CCN2C(=O)Nc1ccc(OC)cc1 +CCOc1nccnc1N1CCC(NC(=O)Cc2ccsc2)C1 +Cc1cc(NS(=O)(=O)c2ccc(Br)cc2)ccc1N +CCc1ccc(CC(=O)Nc2nc(C)c(C(C)=O)s2)cc1 +NC(=O)c1cnc(N2CCCC(C(F)(F)F)C2)c(Cl)c1 +CCOc1cc(CNc2cc(F)ccc2C)ccc1O +NC(=O)CC1COCCN1C(=O)c1scc2c1OCCO2 +Cc1ccc(S(=O)(=O)NCc2ccccc2)cc1C(N)=O +COc1ccc(-c2cc(C(=O)NCc3ccccc3)n[nH]2)c(OC)c1 +Cc1cc(C(=O)N2Cc3nnn(C)c3C(COCC3CC3)C2)c(C)[nH]1 +CC1CN(C(=O)CN2CCN(c3ncccn3)CC2)CC1(O)C1CC1 +CC(C)Oc1ccccc1NC(=O)N1CCC(Cc2cnn(C)c2)C1 +Cc1c(Cl)cccc1S(=O)(=O)N(C)C(C)c1ccco1 +CC1Oc2cc(N)ccc2N(CCOc2ccccc2)C1=O +CCNC(=O)CN1CCN(C(C)C(=O)N2CCc3ccccc32)CC1 +CC(=O)NCC(=O)Nc1cc(C(=O)N(C)C)ccc1C +CCn1ncc(-c2ccc(OC)c(OC)c2)c(CC#N)c1=O +CC(=O)NC(C(=O)NC(C)c1ccco1)C(C)C +COc1cccc(-n2c(C)c(C)c3c2ncn2nc(C)nc32)c1 +COc1ccc(-c2nnc(NC(=O)CCc3ccccc3)o2)cc1 +O=C(CCCn1ccc2cc(Cl)ccc21)NCc1ccc(O)cc1 +CC(C)Oc1ccc(OC2CC2)c(S(N)(=O)=O)n1 +O=c1[nH]c2ccccc2n1CCOc1cccc(Cl)c1 +Cc1c(C(=O)NCCCCC(C)(C)C)cnn1-c1ccncc1 +CCOc1ccccc1Nc1ccc(C#N)cc1N +O=C(NC1CCSc2ccccc21)c1ccnc(-n2cncn2)c1 +C#CCN1CCC(CN(C)C(=O)OC(C)(C)C)CC1 +NC(=O)C1CCN(C(=O)c2ccc(Cl)c(N)c2)CC1 +Cc1n[nH]c(C)c1C(C)CC(=O)NCc1cc(Cl)ccn1 +CC(=O)c1cccc(OCC(=O)c2cccs2)c1 +Cc1nn(C)c(C)c1C(=O)NC(C)c1ccc(Cl)cc1Cl +Cc1ccc(C(O)CC=Cn2nc(C)cc2C)cc1 +CCSc1nnc(NC(=O)CCc2c(C)noc2C)s1 +Cc1oc(-c2cccs2)nc1C(=O)NCCN1CC(C)OC(C)C1 +Cc1cc(F)ccc1NC(=O)N1CCOC(C)(C)C1 +COC(=O)c1ccc(OCCN2CCOCC2C2CC2)c(Cl)c1 +CC(C)(C)OCCSc1nnnn1-c1ccc(Cl)cc1 +CC(=O)Nc1nonc1-c1nc2ccccc2n1CCC(C)C +COc1ccc2c(c1)CN(C(=O)c1cccc(OCC(F)F)n1)CC2 +OCC1(Nc2ccnc(C(F)(F)F)n2)CCCC1 +CS(=O)(=O)N(CC(=O)NC1CCCC1)c1ccc(Cl)cc1 +Brc1cccc(CCc2nc(C3CC3)no2)c1 +COc1ccc2nc(S(=O)Cc3[nH]cc(C)c(=O)c3C)[nH]c2c1 +CC(C)c1cc(C(=O)N2CCc3cc(F)ccc3C2)n(C)n1 +COc1cc(OC)c(NC(=O)c2cc(F)ccc2C)cc1F +Cc1ccc2[nH]c(C(=O)NC3(c4ncon4)CCOCC3)cc2c1C +CCCOCC(=O)Nc1ccc(C)c(Br)c1 +CC(C)CN(C(=O)c1cnc2c(cnn2Cc2ccccc2)c1)C1CC1 +CC(=O)C(C)n1nc(CO)cc1-c1ccc(N(C)C)cc1 +CCn1cnnc1CNc1ncnc2sc(-c3ccccc3)cc12 +COc1ccc(C)cc1C(O)CN1CCOCC1 +O=C(c1cnn2cccnc12)N1CCCN(c2ccc(F)cc2)CC1 +COc1ccc(C(C)NC(=O)CN(C)S(C)(=O)=O)cc1F +CC(=O)c1cn(CC(=O)NC2CC2)c2ccccc12 +Cc1cc(C)n(-c2nc(CC(=O)Nc3ccc(F)cc3)cs2)n1 +COc1ccc(CNc2nc(C(C)C)nc(OC)c2N)cc1 +CCC(O)Cn1ncnc1CCCn1cncn1 +NCc1cnc(-c2ccc(F)cc2)cc1C(F)(F)F +CN(CC(=O)NC(C)(C)C)S(=O)(=O)c1ccc(F)c(Cl)c1 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+COCC1CCCN(c2nc3nonc3nc2N2CCCCCC2)C1 +COc1ccc(OC)c(CNc2ccccc2-n2ccc(C)n2)c1 +Cc1cccc(N(CCC(N)=O)C(=O)c2ccc3ncccc3c2)c1 +COc1ccc(C(=O)N2CCN(C(=O)c3cc(C)oc3C)CC2)nn1 +CCCNC(=O)C1CCCN(C(=O)c2cccc(NC(N)=O)c2)C1 +CC(CC#N)Sc1ccccc1NC(=O)NC(C(N)=O)C(C)(C)C +COCC(=O)N1CCCC(c2cccc(Cc3ccccc3)n2)C1 +CC(=O)NCCNC(=O)NCc1ccc(C)s1 +c1ccc2c(c1)nc(NCC1CCCO1)c1nnnn12 +CCNc1nc(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)cs1 +c1cc(CCn2ccc(NCc3ccc(-n4ccnc4)cc3)n2)ccn1 +COc1cc(OC)c(NC(=O)NCC(O)c2ccco2)cc1Cl +Cc1ccc(N2CCCN(C(=O)c3ccc4nncn4c3)CC2)nn1 +O=C(CCN1CCOC1=O)Nc1ccc(Cl)cc1F +N#Cc1ccc(-c2noc(-c3ccc4nncn4c3)n2)nc1 +CC(C)CNC(=O)c1cnc(C2CCCCC2)nc1N +O=C(c1cccs1)N1CCCC1c1nnc(Cc2ccccc2)o1 +COc1ccc(-c2nc3c(N)cccc3[nH]2)cc1OC +Cn1c(=O)c2c(ncn2Cc2noc(-c3ccco3)n2)n(C)c1=O +O=C(CCc1nc(-c2ccccn2)no1)OCC#Cc1ccccc1 +CC(Oc1ccccc1)C(=O)NC1CCN(C(=O)c2ccco2)CC1 +CCc1cccc(Oc2ccc(NC(=O)N(CC)CCO)cn2)c1 +Cc1occc1-c1nnc(SCc2cc(=O)n3ccccc3n2)o1 +Nc1cccc(CNS(=O)(=O)C2CCCCC2)c1 +CNC(=O)NC1CC(=O)N(c2cccc(F)c2)C1 +C=CCNC(=O)c1cc2c(n(-c3ccc(C)cc3)c1=O)CCCC2=O +CCc1ccccc1OC(=O)c1cc(C(N)=O)cn1C +CC1CCCC(C)N1C(=O)COC(=O)c1ccc(N)cc1 +COCCCN(Cc1ccc(F)cc1)C(=O)c1ccon1 +COc1cccc(NC(=O)c2cc(S(N)(=O)=O)ccc2Cl)c1 +COCC(=O)N1CCC(C(=O)N2CCCCC2)CC1 +Cc1c(C(=O)NC2CCCC2)nnn1-c1ccc(Br)cc1 +Cc1cccc(OCCN(C)C(=O)NCc2ccnn2C)c1 +Cc1ccc(N2CCC3OCCC(C(=O)NCC4CC4)C3C2)nn1 +CCOC(=O)CCC1NCCc2ccc(OC)c(OC)c21 +CC1=CC(C)=NC1C(=O)N1CC(=O)N(c2ccccc2C)C(C)C1 +CNC(=O)NCC(=O)NCC1(O)CCCCCC1 +COc1c(F)cc(NC(=O)c2cccc(F)c2)cc1F +Cc1cc(NC(=O)c2ccc(N3C(=O)C(C)CS3(=O)=O)cc2)no1 +COc1cccc(CN(C)C(=O)CNc2cc(F)ccc2C)c1OC +CC(=O)c1ccc2c(c1)N(C(C)C(=O)OCC(C)C)C(=O)CO2 +O=C(Nc1ccccc1C(=O)N1CCOCC1)C1CCCO1 +CC(NC(=O)c1nccnc1C(N)=O)c1csc2ccccc12 +CCc1onc(C)c1NC(=O)N1CC(C)OC(C)C1 +O=C(COc1ccc2ccccc2c1)N1CCNCC1 +CC(C(=O)Nc1ccccn1)n1nc(-c2ccc(F)cc2)ccc1=O +CC(NS(=O)(=O)c1cn[nH]c1)c1cccc(Cl)c1 +CCn1cc(-c2cc(C(F)(F)F)n3nc(C)c(Cl)c3n2)c(C)n1 +N#Cc1ccc(F)c(CN2C(=O)c3ccccc3S2(=O)=O)c1 +Cc1cccc(C)c1OCCCNC(=O)Cn1ccc(=O)n(C)c1=O +CCN(Cc1cccc(NC(=O)C2CC3C=CC2C3)c1)C(C)=O +CC(C)OCCCNC(=O)c1n[nH]cc1Br +CC(NC(=O)Cn1nnc(COc2ccccc2)n1)C1CCCO1 +Cc1nc2ccccc2c(-c2ccccc2)c1C(N)=O +O=C(NCc1nc2ccccc2[nH]1)C1CCCCC1 +O=C(Cc1ccc[nH]1)NC1(c2ccccc2)CCCC1 +O=C(CCn1cnc2sccc2c1=O)NCCc1ccccn1 +CN1C(=O)CCc2cc(C(O)C3CCCCC3)ccc21 +CCN(CC)S(=O)(=O)Cc1cccc(Cl)c1 +CN1CCSc2ccc(S(=O)(=O)N3CCc4ccccc43)cc21 +CN1CCN(Cc2noc(C3CCCO3)n2)C1=O +O=C(COc1nnc2ccccn12)NC1CCCC1 +O=C(Nc1nccs1)C1CCN(C(=O)CC2CCCCC2)CC1 +O=C(Nc1ccccc1S(=O)(=O)N1CCCC1)c1cnccn1 +COCc1nc(C(=O)N2CCC(C)CC2C)cs1 +COc1cccc(C(C)NC(=O)COC(=O)c2ccc(C#N)cc2)c1 +Cc1c(Cl)cccc1NCCn1nc2ccccn2c1=O +CCOc1ccc(NC(=O)N2CCC(CO)CC2)cc1Cl +Cc1ccc(S(=O)(=O)N2CCc3ccccc3C2)cc1C(N)=O +Cc1nc(C(=O)N2CCC(c3ccc4c(c3)OCO4)C(O)C2)c(C)o1 +COc1ccc(-c2cc(C#N)c(=O)n(C)n2)c(OC)c1OC +Cc1nn(C)c(C)c1OS(=O)(=O)c1cccs1 +CCCc1cc(C(=O)NCc2nncn2CC)sc1C +Cc1csc(CCCCNC(=O)Cc2ccc(F)c(F)c2)n1 +CCC(NC(=O)NCc1cn(C)nc1C(F)(F)F)C1CCCO1 +CC(=O)Oc1ccc(C(=O)N=c2sccn2C)cc1 +CCC(c1ccccc1)c1nc(-c2ccccn2)no1 +O=C(NCc1cn[nH]c1)c1c(F)cccc1Cl +CN(c1ccccc1)C1CCN(S(=O)(=O)c2cccs2)CC1 +CC1CC(C)CN(C(=O)c2cnc3c(c2)c(=O)n(C)c(=O)n3C)C1 +O=C(Cc1cccc(O)c1)NCCOCC1CCOC1 +COc1cc2c(cc1OC)CN(CC1(C#N)CCCC1)CC2 +CNC(=O)C(C)NC(=O)c1ccnc(SC)c1 +CCOc1ccc(C(F)(F)F)cc1NC(=O)C1CC2CCC1O2 +COC(=O)C1=C(C)NC(=O)NC1c1cc(Cl)cc(OC)c1OC +COc1ccc(-c2ccc(CC#N)c(C)n2)cc1C +O=C(N1CC(O)C1)C1(c2cccc(F)c2)CCCC1 +Cc1ccnc(NC(=O)c2ccccc2OCC2CCCO2)c1 +CC1=NS(=O)(=O)c2cc(C(=O)NC3CC3)ccc2N1CC(C)C +CC(=O)N1CCN(Cc2nc3c(c(=O)[nH]c(=O)n3C)n2C)CC1 +CC1CCC(NC(=O)c2ccccc2NS(C)(=O)=O)CC1 +CC(=O)c1cc(C(=O)NCc2cc(Cl)c3c(c2)OCCO3)n(C)c1 +CN(Cc1ccc(F)cc1)C(=O)NCc1cnn(C)c1 +Cc1ccc(NC(=O)Cn2ncc3c([nH]c4ccccc43)c2=O)cc1C +O=C1C2CCC(CN(c3cnc4ccccc4n3)C2)N1CC1CC1 +CC1CC1C(=O)Nc1nc(-c2ccc3c(c2)OCCO3)cs1 +O=C(Nc1ccc2ncccc2c1)c1ccc(F)nc1 +O=C(COC(=O)Cc1cccs1)Nc1cc(F)ccc1F +CC(C)C(=O)N1CCCC1C(=O)NCCC(=O)N1CCCC1 +COC(=O)c1ncn(Cc2sc3ccccc3c2Cl)n1 +COc1ccccc1N1CCN(C(=O)Nc2cccnc2)CC1 +O=C(CC1CC1)N1CCCn2cnc(COCc3ccco3)c2C1 +CC(O)C1CCN(C(=O)C2Cc3cc(F)ccc3O2)CC1 +COc1cn(-c2ccccc2)nc1C(=O)Nc1ccc2nccnc2c1 +CCOC(=O)c1cc(N)ccc1NCC1CCOC1 +O=C(COc1ccccc1)N1CCN(Cc2noc(C3CC3)n2)CC1 +COC(C)(C)CC(C)Nc1ccc(S(C)=O)cc1 +Cc1ccc(C(=O)Nc2nc(-c3ccc(F)c(Cl)c3)cs2)cn1 +COc1cccc2cc(C(=O)N3CCCC3C(=O)N(C)C)oc12 +O=C(Nc1ccccc1F)N1CCN(CC(O)c2ccccc2)CC1 +NC(=O)c1ccccc1NC(=O)c1ccccc1Br +Cc1noc(COc2cccc(-c3noc(C)n3)c2)n1 +CN(C)C(=O)COc1ccc(S(=O)(=O)NC2CC2)cc1Cl +CN(C)C(C(=O)N1CCCC1)c1cccc(F)c1 +COc1ccc(C(C)NC(=O)CN(C)S(C)(=O)=O)c(OC)c1 +CCOc1cc(C#N)ccc1OCC(=O)N1CCN(CC(C)O)CC1 +N#CC(CCC(=O)NCc1cccnc1)c1ccccn1 +CC(=O)Nc1nc2ccc(NC(=O)c3ccncc3)cc2s1 +O=C(Cc1ccc(F)c(Br)c1)NCC(=O)NC1CC1 +COc1ccc(CCC(=O)NCC2(O)CCOc3ccccc32)cc1 +Cc1cc(C)c(NC(=O)CNc2nccc(C(F)(F)F)n2)c(C)c1 +COCC(NC(=O)NCc1cccc(Cl)c1)c1ccco1 +Cc1cc(C)n(CC(O)COc2ccc3ccccc3c2)n1 +Cc1cccc(CN2CCN(C(=O)Nc3nncs3)CC2)c1 +COc1cc(C)c(CNC(C(N)=O)C(C)C)cc1OC +Nc1cccc(NC(=O)CCCn2cc(Br)cn2)c1 +CCC1C(=O)NCCN1Cc1c(F)cccc1F +Cc1nnc2ccc(NC3CCN(c4ccc(C#N)cc4)CC3)nn12 +COc1cccc2cc(C(=O)Nc3ccc(-n4ccnc4)cc3)oc12 +N#CCSc1nnc(-c2ccncc2)n1C1CC1 +Cn1nccc1CNc1cccc(-c2cnco2)c1 +Cc1ccc(NC2CCCN(C(=O)c3ccoc3)C2)cc1C +Cc1c(Br)cccc1NC(=O)NCc1ncc[nH]1 +COc1c(F)cc(NC(=O)c2ccc(CNC(C)=O)cc2)cc1F +O=C(Cc1noc2ccccc12)Nc1ccc2c(c1)NCCC2 +CC(Sc1ccccn1)C(=O)Nc1ccc2c(c1)CCC2 +CCC(CC(=O)NCc1c[nH]nc1C)c1ccccc1 +CNC(=O)CCCN(C)Cc1cnc(C(C)(C)C)s1 +COc1ccc(NC(=O)C2Cc3ccccc32)cc1NC(C)=O +CCOCC(=O)Nn1cnc2c(cnn2-c2ccccc2)c1=O +Cn1ccc(-c2nnc(NC(=O)c3cc(-c4ccccc4)on3)o2)n1 +CCCC(=O)N1CCCC(C(=O)N2CCc3cc(F)ccc3C2)C1 +O=C(Nc1cc(F)ccc1F)N(Cc1cccnc1)CC1CCCO1 +CCCc1cc(=O)[nH]c(SCc2nnc(Cc3ccccc3)o2)n1 +O=C1OCCN1CCCSc1ccccc1Cl +CC(C(=O)NCCOc1ccc2c(c1)CCC2)n1cncn1 +COC(=O)C(CO)NCc1ccc(NC(C)=O)cc1 +CCn1cc(NC(=O)c2cnn(-c3ccccn3)c2C)cn1 +Cc1cc(CNC(=O)N2CCN(Cc3ccccc3)C(C)(C)C2)on1 +CC(=O)N1CC(C)CN(C(=O)C2CC=CCC2)c2ccccc21 +O=C(CCOc1ccccc1)Nc1cccc(-c2nc[nH]n2)c1 +CCS(=O)(=O)c1ccccc1C(=O)N(C)CCc1ccc(F)cc1 +CCNC(=O)C(C)(C)CNC(=O)NCC(C)(C)c1ccncc1 +COc1cc(C)c(Cl)cc1S(=O)(=O)N1CCN(CCO)CC1 +CC1CN(C(=O)CNc2ccc(C(N)=O)cc2)CCO1 +CCOC(=O)C1N=C(C)C(CCC(=O)Nc2c(C)cccc2C)=C1C +COc1ccc(S(=O)(=O)NC(C)CN2CCOCC2)cc1F +COc1ccc(C(C)C)cc1C(=O)CCC(=O)N(C)C +CCn1nnc2cc(C(=O)NC3CCc4nnc(C)n4C3)ccc21 +O=C(NC1CCc2cc(F)ccc21)c1ccc(F)nc1 +Cc1cc(C(F)(F)F)n(C(=O)c2ccccc2)n1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)c2scnc2C2CC2)c1 +CCN1CC2(CCN(C(=O)CC3CC4C=CC3C4)CC2)CC1=O +CC(CNC(=O)NC1CCc2c(O)cccc21)c1nccs1 +CC(=O)Nc1cccc(-n2c(C)nnc2SCC(=O)C(C)(C)C)c1 +CCc1nc(CNc2cccc(N3CCCC3=O)c2)cs1 +Cc1oncc1C(=O)N1CCc2c(cnn2-c2ccccc2)C1 +CC(=O)Nc1ccc(O)c(C(=O)NCC2CCCC(C)C2)c1 +Cc1n[nH]c(C)c1NC(=O)c1ccc(OC(F)F)cc1 +N#CCCC(=O)N1CCN(c2ccc(F)cc2)CC1 +O=C(NC1CC1)c1ccc2c(c1)NC(=O)C(N1CCOCC1)S2 +CCCC(=O)NCCCc1cn(-c2ccccc2)nc1C +Cc1cc(NC(=O)Cc2ccc(F)cc2)ccc1N1CCCC1=O +CCCN1C(=O)c2ccccc2CC1(C)C(=O)NC1CCC(C)CC1 +CC(=O)Nc1cccc(CNC(=O)NCC2CC2C)c1 +CCN(c1ccc(Br)cn1)S(=O)(=O)c1cnn(C)c1 +COc1ccc(N2CCN(CC(=O)N3CCCC3)C2=O)cc1 +CCn1c(=O)c2ccccc2n2c(Cn3nc(C)cc3C)nnc12 +CCc1ccccc1NC(=O)COc1ncnc2oc(C)c(C)c12 +CNC(=O)c1cc(Cl)ccc1NC(=O)c1ccc(OC)c(OC)c1 +CSc1ccccc1C(=O)N1CCN(c2ncccn2)CC1 +COCCNc1nc(-c2ccc(OC)cc2)cc(=O)[nH]1 +COc1cc(CNC(=O)c2ccc[nH]c2=O)ccc1C +O=C(Nc1ccccc1)N1CCC2(CC1)OCCO2 +C=CCNC(=O)c1nnn(-c2cccc(C)c2)c1COC +O=C(Nc1c[nH]cc(Br)c1=O)c1cnccn1 +NC(=O)CCn1nc(-c2ccc(F)c(F)c2F)c2c1CCNC2 +CC(=O)Nc1ccccc1-c1nc(-c2cccs2)no1 +COCCNC(=O)CC1CCN(C(=O)C2N=C(C)C=C2C)CC1 +COc1cccc(CCCn2cnc3ncccc3c2=O)c1 +COc1ccc2c(CSc3ncccn3)cc(=O)oc2c1 +CC(NS(C)(=O)=O)c1nc(C2CCCC2)nn1CCO +Oc1nc(-c2ccncc2)sc1-c1ccccc1 +CC1CCN(C(=O)C(C)NS(=O)(=O)c2ccccc2F)CC1 +CC(=O)Nc1cccc(NC(=O)CCS(=O)(=O)c2ccccc2)c1 +Cc1ncc(CN(CCC#N)CC2CC2)n1-c1ccccc1 +COC(=O)c1cc(N)ccc1N(CCO)C(C)C +CC(C)Cn1ncc2cc(C(=O)N3CCc4cncnc4C3)cnc21 +CCOc1cccc(NC(=O)c2ccccc2N(C)S(C)(=O)=O)c1 +N#CCCSc1nccn1-c1ccc(F)c(Cl)c1 +Cc1cc(F)ccc1C(N)C(=O)NCC1CCCO1 +CCCC1CN(C(=O)CC(C)c2ccccc2OC)CCO1 +CCN(C(=O)CCCOc1ccccc1)c1ccccc1 +Cc1ccccc1NC(=O)c1csc(-n2cccc2)n1 +COc1cc(C(C)=O)ccc1OC(=O)C1CCCO1 +CC(CNS(=O)(=O)c1ccc(F)c(Cl)c1)Cn1cccn1 +COc1ccc(OC)c(C(=O)CCC(=O)NC(C)(C)C)c1 +Cc1nc2sc(SCC(=O)NC(C)(C)C)cc2c(=O)n1C +CCCn1c(=NC(=O)CN2CCCCC2=O)[nH]c2ccccc21 +CC(=O)N1CCC(C(=O)Nc2cc(C)cc3cccnc23)CC1 +CC(Oc1cccc(F)c1)C(=O)Nc1ccccc1 +CN(CCO)C(=O)C(c1ccccc1)c1ccccc1 +Fc1ccc(CNCCc2ccco2)c(Cl)c1 +CCOC(=O)C1(NS(=O)(=O)c2cnn(C)c2)CCCCC1 +Cc1ccc(-c2ccc(=O)n(C(C)C(N)=O)n2)cc1 +CC1CC(C)CN(C(=O)c2ccc3c(=O)n(C)c(=O)n(C)c3n2)C1 +COc1ccc(C2(Cc3sccc3C)NC(N)=NC2=O)cc1OC +Cc1csc(C2(NS(=O)(=O)c3ccccc3)CCCC2)n1 +CC(C(=O)N(C)C1CCCCC1)N1CCOCC1 +COc1ccc(F)cc1NC(=O)C1CC2C=CC1C2 +COCC(=O)N1CCN(c2ccc(OC)cc2OC)C(=O)C1C +NC(=O)C1CN(c2ncnc3sc4c(c23)CCCC4)CCN1 +CCN(CCC(=O)OC)C(=O)c1cc(C)oc1C +c1cncc(CNCc2csc(-c3ccco3)n2)c1 +Nc1ccc(Br)c(N2CCOCC2)c1 +Cn1c(C(=O)NC2CC2)nc2cc3c(cc21)OCCO3 +Cc1ccc(CN(C)S(=O)(=O)N2CCCC(C)C2)o1 +O=C(NC1CCCC1)c1nnc(Cc2ccc(F)cc2)o1 +O=C(c1cnccn1)N1CCCC(CCc2ccc(F)c(F)c2)C1 +O=C(NCc1ccc(F)cc1)c1c[nH]nc1-c1ccccc1F +Cc1cccc(OCCCNC(=O)CN2CC(C)OC(C)C2)c1 +CCCNC(=O)c1cccc(C(=O)N(CC)c2nc(C)cs2)c1 +O=C(C1CCC1)N1CC2CCC(C1)N(C(=O)CCCc1cn[nH]c1)C2 +O=C(c1csc2c1CCCC2)N1CCC2(CC1)OCCO2 +CC(=O)NC(C(=O)NC(C)COc1cccc(C)c1)C(C)C +N#Cc1noc(C(=O)Nc2ccccc2C(F)(F)F)c1N +CCN(CC(C)C#N)C(=O)c1ccc(C)c(Cl)c1 +CC(=O)Nc1nc(-c2ccc3c(c2)N(C)C(=O)CO3)cs1 +CCC(=O)N1CCCC(C(=O)Nc2ccc(F)cc2Cl)C1 +Cc1ccc(C(=O)CSc2n[nH]c(=O)[nH]c2=O)cc1 +CC(C)(C)NC(=O)CNC(=O)NCc1nc2ccccc2s1 +O=C(Cn1nc2n(c1=O)CCCCC2)N1CCc2cc(F)ccc2C1 +N#Cc1ccc(Cl)cc1NC(=O)c1csc(-c2cnccn2)n1 +CC(C)(C)c1nnc(NCc2nc3c(s2)CCC3)o1 +CCN(CC1COc2ccccc2O1)C(=O)CCc1nc(C)no1 +Cc1ccc(C)c(S(=O)(=O)NCCc2ccc(O)cc2)c1 +Cc1c(C(=O)NCc2cccnc2)nnn1-c1ccc(C(C)C)cc1 +CCCn1c(=NC(=O)CCC(=O)N(CC)CC)[nH]c2ccccc21 +CCOc1ccccc1-c1cc(C#N)nn1CC(=O)OC +CC1CC(C)CN(C(=O)CN(C)S(=O)(=O)c2ccccc2)C1 +CS(=O)(=O)Nc1ccc(CC(=O)NC2CC2)cc1 +O=C(Nc1ccc2c(c1)COC2)N(CCO)Cc1ccccc1 +CCOC(=O)c1cnc(N2CCC(C)CC2)nc1N +Clc1cc2ncc(N3CCC(c4nc[nH]n4)CC3)nc2cc1Cl +CCOC(=O)Cc1nc2ccc(Cl)cn2c1CC#N +O=C(Nc1nnc(C2CC2)s1)c1ccc(-c2ccccc2F)o1 +Cc1nnnn1-c1ccc(CC(=O)Nc2ccccc2C2CC2)cc1 +O=C(CCSc1ccc(Br)cc1)N1CCC(O)CC1 +Cc1cc(C)nc(OC2CCCN(C(=O)OC(C)(C)C)C2)n1 +O=C1OCCC1Sc1ncnc2sccc12 +Cc1ccnc(SCC(=O)N2CCOCC2)n1 +CN1CCC(Sc2nc3ccccc3n2-c2ccccc2)C1=O +COC(=O)C1CC2CCCCC2N1Cc1nc2c(cnn2C)c(=O)[nH]1 +CCN(CCO)C(=O)CCc1c(F)cccc1F +CCC(C)NC(=O)c1ccc(CN2C(=O)CSc3ccccc32)o1 +Cc1cccc(OCC(=O)NCc2cc(-c3ccccc3)no2)c1 +O=c1ccccn1CCc1cc(Cl)c2c(c1)OCCCO2 +CCCCC(=O)NCC(O)c1cc(F)ccc1F +CC(C)c1ccc(C(NC(=O)NCc2ncn(C)n2)C(C)C)cc1 +CNc1cnc(C(C)C)nc1C(=O)NC1CC1(C)C +Cc1ccc(-c2nn3c(C)nnc3s2)cc1NC(=O)CC(C)C +C=CCN(C)S(=O)(=O)c1ccc(NCc2ccc(C#N)cc2)cc1 +O=C(c1csc2c1CCCC2)N1CCC(O)CC1 +CCCn1nc(C(=O)OCc2cc(-c3ccco3)on2)ccc1=O +O=C(c1ccsc1)N1CCC(O)C1Cc1ccncc1 +Nc1nccnc1C(=O)N1CCN(CC2CCCCC2)CC1 +COc1ccccc1S(=O)(=O)N1CCOC(C)(C)C1 +Cc1nc(NCc2ccccc2)[nH]c(=O)c1CCO +N#Cc1ccc(C(=O)NCc2ccccc2Cn2cncn2)cc1 +NC(=O)c1ccc(Cn2cc(Br)cn2)cc1 +Cc1noc(C(C)Sc2ccccc2Cl)n1 +Cc1c(-c2nc(-c3ccc(C#N)cn3)no2)cnn1C +Cc1cc2c(cc1S(=O)(=O)N(C)Cc1ccccc1)OCC(=O)N2 +Cc1ccccc1C(=O)NCC1(C(N)=O)CCOCC1 +COc1ccc(OC)c(C(C)NC(=O)Cn2cnc(C#N)n2)c1 +COc1ccc(OC)c(-c2cc(C#N)nn2CCO)c1 +Cc1n[nH]c(C)c1NC(=O)Nc1cnc2c(c1)c(C)nn2C +Cn1c(N)nnc1SCc1ccc(Cl)cc1 +COCCn1cc(CC(=O)Nc2c(C)nn(C)c2C)c2ccccc21 +COC(=O)c1scc(-c2cccc(Cl)c2)c1N +CCC(O)c1cnn(Cc2ccc(Cl)c(Cl)c2)c1 +Cn1ccnc1COC(=O)c1c[nH]nc1-c1ccccc1Cl +Cc1ccc(S(=O)(=O)CC(=O)Nc2cccc(C)c2C)cc1C +COc1ccc(NC(C)C(=O)N2CCOCC2)cn1 +CCc1nn(-c2ccccc2)c(NC(=O)c2cnoc2C2CC2)c1C +CC(C)Cc1cc(C(=O)N2CCCC(O)(CO)C2)on1 +COCCCOc1c(C)cc(S(N)(=O)=O)c(C)c1C +CC(Nc1ccc2c(c1)CC(=O)N2)C(=O)NCCc1ccc(F)cc1 +COC(=O)C1(NS(=O)(=O)c2ccc(F)cc2Cl)CCCC1 +CCOC(=O)C1C2C=CC3(CN(c4cccc(C)c4)C(=O)C13)O2 +CN(C(=O)c1cccnc1OCC(F)F)c1nc2ccccc2o1 +COC(=O)C(NC(=O)c1cc(C)ccc1F)C(C)C +COC(=O)CCC(=O)c1ccc(Br)c2ccccc12 +Cc1ccc(C(=O)Nc2cnn(Cc3ccc(F)cc3)c2)s1 +O=C(NCc1ccccc1)C1CC2CN(c3ncc(F)cn3)CC1O2 +O=C(Nc1cccc(OCc2ccccn2)c1)C1Cc2ccccc2O1 +COC(=O)COc1cccc(NC(=O)CN(C)C(C)=O)c1 +NC(=O)c1cn(Cc2ccccn2)c2cccc(N)c2c1=O +O=C(OCc1nc(-c2cccs2)no1)C1CC2CCCC(C1)C2=O +O=S(=O)(c1cc(F)ccc1F)N1CCOc2ccc(F)cc21 +O=C(COC(=O)Cc1ccc(F)cc1)NCc1ccc(F)cc1 +Cc1nc(-c2cc(C(=O)NCC(C)N3CCOCC3)n(C)c2)cs1 +Cc1ccnc(Sc2ccc(Br)cn2)n1 +Cc1c(C(=O)N2CCOC3CCCCC32)cnn1-c1ccncc1 +CC(C)NC(=O)c1ccc(NC(=O)c2cc3ccncc3cn2)cc1 +Cc1ccn2c(=NC(=O)c3csc(-c4cnn(C)c4)n3)[nH]nc2c1 +Cc1cc(CCNC(=O)Cc2c[nH]c3ccccc23)on1 +CC(=O)N1CCc2cc(NC(=O)CSc3ccc(F)cc3)ccc21 +CCCNC(=O)COC(=O)c1nn(-c2ccccc2)c2c1CCC2 +C#CCNC(=O)c1ccc(NCc2ccc(OC(C)C)nc2)nc1 +COc1ccc(C)cc1CCOc1cccc(N)c1 +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)C(C)(C)C +Cc1ccccc1CN(C)C(=O)Cn1c(=O)oc2cc(Cl)ccc21 +c1ccc(-c2cc(Nc3ncccn3)nc(-c3cccnc3)n2)cc1 +O=S(=O)(Nc1ccnc2ccccc12)c1ccccc1 +CCOC(=O)C(N)Cc1cccc(-n2ccnc2)c1F +COCCOc1ccc(NC(=O)C(C)NC(C)=O)cc1F +CC(=O)Nc1ccc(C(=O)OCCOc2cccc(C)c2)s1 +Cc1ccccc1C(=O)Nc1ccc2c(c1)CC(=O)N2 +CCCCN(C)c1ccc(S(C)(=O)=O)cc1N +N#Cc1ccc(N2CCC(NC(=O)c3cccnc3)CC2)nc1 +CCOC(=O)c1sc(NC(=O)COc2ccc(C)cc2C)nc1C +Cc1nc2ncc(C(=O)N3CCOCC3)c(C)n2n1 +O=C(NC1CC(=O)N(Cc2ccccc2)C1)C1CCCC1 +CCc1ccsc1C(=O)N(C)CCN(C)C(=O)OC(C)(C)C +COc1ccc(CNC(=O)C(C)Oc2ccc(C#N)cc2)cc1O +CC(C)(C)c1nc(CNC(=O)c2scnc2C2CC2)no1 +CSc1nc2ncn(CCCOc3ccccc3C)c(=O)c2s1 +O=C(Nc1cccc(OCCn2cncn2)c1)c1cn2cccnc2n1 +CSc1ccc(OCC(=O)Nc2c(C)cccc2C)cc1 +CCCn1ccc2cc(NC(=O)c3cc(C4CC4)on3)ccc21 +N#Cc1ncn(Cc2nnnn2-c2ccccc2)n1 +CCc1nc2onc(C)c2c(=O)n1CC(=O)NCCc1cccs1 +Nc1nonc1-c1nnc(COc2ccc(F)cc2)o1 +CCn1cnnc1CNC(=O)NC(C)c1ccc2c(c1)CC(=O)N2 +Cn1c(=O)cc(NCc2ccncc2)n(Cc2ccccc2)c1=O +CCc1cccc(C)c1NC(=O)Cn1c(=O)sc2ccccc21 +COCCCNC(=O)CSc1nc2sccc2c(=O)[nH]1 +Cc1ccc(-n2cnnc2SCC(=O)NCCO)cc1C +N#CCCN(CCC(F)(F)F)C(=O)c1ccsc1 +COc1ccc(C(=O)Nc2ccc(Cl)cc2C(N)=O)c(OC)c1 +Cc1ccc2nc(NC(=O)CCSc3cc(C)ncn3)sc2c1 +CC(C)c1nnc2n1CCN(CCCS(=O)(=O)c1ccccc1)C2 +COc1ccc(Cl)cc1-c1cn[nH]c(=O)c1CO +Cn1ncc(Cl)c1C(=O)Nc1ccc2c(c1)CCC2 +Cc1occc1C(=O)NCC(=O)NCCOc1ccc2c(c1)CCC2 +c1ccc2oc(Sc3nnnn3CC3CCCO3)nc2c1 +COc1ccc(S(=O)(=O)NCC2CN3CCCCC3CO2)cc1 +COc1ncccc1CNS(=O)(=O)N1CC(C)CC(C)C1 +CNC(=O)C1CCC(NC(=O)c2ccccc2O)CC1 +Cc1ccc(NS(=O)(=O)c2ccc(Br)cc2)cc1N +Cc1ccc(S(=O)(=O)NCc2ccc(C(=O)N(C)C)cc2)cc1 +Cc1[nH]ncc1C(=O)Nc1ccc(NC2CCOCC2)cc1 +O=C(NCCn1ccc(C(F)(F)F)n1)Nc1ccccc1Cl +COc1ccccc1CC(=O)NC1CCCCNC1=O +Cc1cc(C(=O)NC(C)(CO)C2CCCCC2)no1 +Cc1cnc(CCNC(=O)c2cnn(C)c2-n2c(C)ccc2C)s1 +COC(=O)c1ccc(C(=O)OC)c(NCC(C)C)c1 +Cc1cc(C)c(NC(=O)c2ccccc2C)c(C)c1 +COCC(C)NC(=O)Nc1ccc(Sc2nc(C)cs2)cc1 +CNC(=O)c1cccc(-n2nccc2-c2ccccc2)c1 +COc1ccc(-c2nc(-c3nnc(C(F)F)o3)c(N)o2)cc1 +COc1ccc(CC(=O)N2CCCC2Cn2nc(C)cc2C)cc1 +CCN1C(Cl)=Nc2c(OC)cccc2S1(=O)=O +COCC(C)NC(=O)c1nnn(-c2cccc(OC)c2)c1C +COCc1cc(C(=O)Nc2cccc(-c3nc[nH]n3)c2)ccc1F +CCCc1nc(C)c(C(=O)Nc2nnc(C3CC3)s2)s1 +Cc1cccc(OCCn2nnc(C#N)c2-c2cccs2)c1 +Cc1csc(SCc2cc(=O)n3cc(Cl)ccc3n2)n1 +Cc1cnc(NC(=O)CCNC(=O)C(C)(C)C)s1 +O=C(CC1C=CCC1)Nc1nc(-c2ccc3c(c2)CCO3)cs1 +CC(=O)N(c1ccccc1)c1nc(CN(C)CC(F)F)cs1 +CCc1ccc2c(CN(C)CC(=O)NC)cc(=O)oc2c1 +CCC(C)(C)C1CCC(NC(=O)CCCc2nc(C)no2)CC1 +COc1ccc(N)cc1NC(=O)c1c(C)cc(C)cc1C +Nc1nc2nnnn2c2c1C1(CCCC1)Cc1ccccc1-2 +Cc1cc(Cl)ccc1S(=O)(=O)NCC1CCOC1 +O=C(Nc1ccccc1N1CCOCC1)c1ccc2c(c1)OCCO2 +CCOc1ccc(-c2cc(N)c(=O)n(CC(C)C)n2)cc1 +Cc1cc(=O)[nH]c(Nc2ccc3c(c2)OCCO3)n1 +CCNC(=O)N1CCN(C(C)C(=O)NC(CC)CC)CC1 +Nc1c(C(=O)c2ccc[nH]2)cnn1-c1ccccc1 +Cc1cccnc1NC(=O)CC1CSc2ncc(C)c(=O)n21 +O=C(Nc1c2c(nn1-c1nc3ccccc3s1)CCC2)C1CC1 +NC(=O)N1CCCC(Nc2ccnc(Cc3ccccc3)n2)C1 +COc1ccc(CCNC(=O)c2ccnn2C)cc1OC +Cn1cc(NC(=O)c2ccc(-c3ccccc3F)s2)ccc1=O +COc1cccc(C(=O)c2ccc(OC)c(OC)c2)n1 +Cn1c(SCC(F)(F)F)nnc1-c1cccs1 +COC(=O)C(C)(C)NC(=O)CCc1cccc(F)c1 +COC(=O)C(CO)Nc1ncnc2onc(C)c12 +Cc1ccc2oc(C(=O)Nc3cccc(CN4CCCC4=O)c3)cc2n1 +Cn1nnnc1SCC(=O)c1ccc(Cl)cc1 +COC(CNS(=O)(=O)c1cnn(C)c1)c1ccc(C)s1 +CC(C)=CC1C(C(=O)N2CCN(C(=O)CO)CC2)C1(C)C +CS(=O)(=O)Nc1ccccc1-c1nc(-c2cccnc2)no1 +COC(=O)Nc1ccc(OC(C)c2nnc(-c3cccs3)o2)cc1 +CCOCCNS(=O)(=O)Cc1c(Cl)cccc1Cl +CCOC(=O)CC(C)CNC(=O)NC1CCc2c(O)cccc21 +COc1cc2nc(CO)n(CCO)c2cc1OC +O=C(C1CCCN(c2ncnc3c2CCC3)C1)N1CCOCC1 +COc1cc(O)cc2c1CCNC2c1ccc(C)nc1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)Nc2ncccc2C)cc1 +Cc1[nH]c(=O)[nH]c(=O)c1-c1ccccc1-c1ccccc1 +COc1ccccc1-c1ccc(=O)n(CC(=O)NC2CCCC2)n1 +Cc1ccc(C)c(C(N)C(=O)NCCCCCO)c1 +CSc1ccc(C(=O)OCCc2scnc2C)cn1 +Cc1noc(C)c1S(=O)(=O)NC(C)c1cccc(Cl)c1 +COC(=O)N1CCC(NC(=O)NCc2ccccc2C)CC1 +CN(CC(N)=O)C(=O)COc1ccc(Nc2ccccc2)cc1 +CCCCN(CC(F)(F)F)C(=O)c1ccc(OC)cc1F +CC1=C(C(N)=O)C(c2ccccc2)C(C(N)=O)=C(N)O1 +COc1nn(C)c2c1CCCN(Cc1cccnc1)C2 +CCN1C(=O)Cc2cc(C(=O)NCc3ccccc3)ccc21 +CCOC(=O)C1(n2[nH]c(=O)n(-c3ccccc3)c2=O)CC(C)OC1=O +O=C(c1ccc(-n2ccnn2)cc1)N1CCOC2(CCOCC2)C1 +CCNc1cc(C(=O)NCc2ccccc2)ccn1 +Cc1nc(-c2ccsc2)sc1C(=O)Nn1cnc2ccccc21 +Cc1cc(C)n(CCOC(=O)C2CC3CCC2O3)n1 +Cc1cc(C)n2nc(SC(C)c3nc(C)no3)nc2n1 +O=C(CC1=CCCCC1)NCC1CN2CCCCC2CO1 +CCc1ccccc1OCCc1cncc(C(N)=O)c1 +O=S(=O)(NCc1ccncc1)c1ccc2c(c1)OCCO2 +Nc1cc(Nc2cccc(C(F)(F)F)c2)nc(C2CC2)n1 +c1cnc(N2CCN(Cc3ncnn3C3CCCCC3)CC2)nc1 +Cc1ccc(Cl)c(OCC(=O)N(C)CCC#N)c1 +Cn1ncc2c1CCc1sc(NC(=O)Cc3cccc(F)c3)nc1-2 +O=C(Cn1cc(C(F)(F)F)ccc1=O)Nc1cccc2ncccc12 +Cn1cc(S(=O)(=O)N2CCc3ccc(N)cc32)cn1 +CC1COCC(C)N1C(=O)c1cc2ccccc2c(=O)[nH]1 +CC1CCC(NC(=O)C(C)Sc2nnc(C3CC3)n2C2CC2)CC1 +O=S(=O)(NC1(C(F)(F)F)OCCO1)c1ccccc1 +COC(=O)c1ccc(CN(C)C(=O)c2ccc(C)cc2O)cc1 +CCCCC(O)c1cc(F)cc2c1OCCC2NC(C)=O +COc1ccc(F)cc1S(=O)(=O)N1CCC2(CC1)OCCCO2 +CCc1ccc(S(=O)(=O)N=c2ccc(CO)c[nH]2)cc1 +CCN(C(=O)CC(C#N)c1cc(C)ccc1OC)c1ccccc1 +COCc1cccc(CNS(=O)(=O)c2ccc(OC)c(C)c2)c1 +CCc1nc(-c2ccc(C(=O)Nc3c(C)noc3CC)cc2)n[nH]1 +CC(Oc1ccccc1)C(=O)Nc1cccc(S(=O)(=O)N(C)C)c1 +CCC(=O)N1CC(OCc2ccc(Cl)cc2)C1 +COC(=O)N1CCCC(C(=O)Nc2cc(F)ccc2OC)C1 +Cc1ccc2[nH]c(=O)c(CCC(=O)NC(C)C)cc2c1 +Cc1ccc(NC(=O)C2CCCN(C(=O)OC(C)(C)C)C2)c(O)c1 +CC(=O)Nc1ccc(CNc2cccc(OC(F)F)c2)cc1 +CCC(=O)c1ccc(OCC(=O)NC2(C#N)CCCC2)cc1 +Cc1cccc(C(=O)NC(C(=O)Nc2cccc(O)c2)C(C)C)c1 +CCC1CN(C(=O)NCc2nnc3n2CCCCC3)CCO1 +C=CCCC(=O)NC1CCCc2nc(N3CCC(CO)CC3)ncc21 +COCc1cc(C)nc2sc3c(=O)[nH]c(C)nc3c12 +Cc1nc2ccc(-c3cnncc3Br)cc2[nH]1 +Cc1nc2ncnn2c(N)c1-c1ccc(Br)cc1 +C=CCOc1ccc(C(=O)NCCS(N)(=O)=O)cc1 +Cn1c2c(cc(C(=O)N3CC(c4ccccn4)C3)c1=O)CCCC2 +CCn1c(=O)n(CC(=O)N2c3ccccc3CCC2C)c2ccccc21 +CCOCCCNC(=O)c1onc(-c2cccc(F)c2)c1N +CCC(C(=O)Nc1ccc(OCC2CC2)cc1)N1CCCC1=O +CCCc1cc(C(=O)N2CCCC2c2c(C)noc2CC)no1 +CCOC(=O)c1cccc(NC(=O)NCc2c(C)nn(C)c2C)c1 +N#Cc1ccccc1OCC(=O)Nc1cccc(F)c1F +O=C(NCc1ccccn1)c1cnn2c1OCCC2 +CN(C(=O)NC1CCN(C(=O)c2ccco2)CC1)C1CCCCC1 +CC(C)(C)Oc1cc(CNC(=O)COc2ccccc2)ccn1 +CC(C)CC(NC(=O)C1CCN(C(=O)C2CC2)CC1)c1ccccc1 +OC(CNCc1ccccc1N1CCOCC1)c1c(F)cccc1F +COCCCNS(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +O=C(NCCNC(=O)C1CC(=O)N(C2CCCC2)C1)C1CCCCC1 +O=c1c2ccccc2nnn1CC(O)c1ccccc1C(F)(F)F +CN1CCN(C(=O)c2cn(C)c(=O)c3c2c2ccccc2n3C)CC1 +CCS(=O)(=O)N1CCN(S(C)(=O)=O)CC1 +O=C(NCc1ccc(Br)cc1Cl)C1CCOCC1 +CN(CC1CCCCC1)S(=O)(=O)c1ccc2c(c1)OCCCO2 +CCN(C(=O)NCCC(=O)N1CCCC1)C1CCCC1 +CC(C)c1ccc(NC(=O)c2c[nH]ccc2=O)cc1 +CCOc1ccc(OCC2NCCc3cc(OC)c(OC)cc32)cc1 +CC1CC(CCC(=O)Nc2ccc(S(N)(=O)=O)cc2)C(=O)O1 +c1ccc(-c2csc(CCNCc3cccnc3)n2)cc1 +CC(OCC1CCCCO1)C(=O)NC(C)c1ccc2[nH]c(=O)[nH]c2c1 +Cc1ccc2nc(Nc3nc(C)c4c(n3)CCCC4=O)ncc2c1 +Cc1ccc(-c2nc3ccc(F)cn3c2CO)cc1 +Cc1ccc(-c2cc(C(=O)Nc3nnc[nH]3)c3ccccc3n2)cc1 +CCC(CC(=O)N(C)c1ccccc1S(C)(=O)=O)c1ccccc1 +COc1cccc2cc(C(=O)Nc3ccc4c(c3)C(=O)NCC4)oc12 +CCc1nc(C)c(C(C)N(C)Cc2cccc(O)c2)s1 +COc1ccc(F)c(CN2CCC(=O)N(CC(C)C)CC2)c1 +NC(=O)C1(CNC(=O)C2CC(=O)N(Cc3ccco3)C2)CCOCC1 +CC1CCN(C(=O)C(NC(=O)c2ccc(F)cc2)C(C)C)CC1 +Cc1[nH]c(=O)ccc1C(=O)Nc1ccc2c(c1)COC2 +O=C(NCc1nnc2n1CCC2)c1ccc(Cl)cc1Cl +CCNc1cncc(S(=O)(=O)NC2CCCC2)c1 +CC(C)C(NC(=O)NCc1cccnc1-n1ccnc1)c1ccccc1 +COc1ccccc1NC(=O)N1CCc2ccccc2C1 +CCc1nnc(N2CCN(C)C3(CCNC(=O)CC3)C2)s1 +COc1cccc(C(=O)N2CCCCC2CNC(N)=O)c1 +Cc1cnn(CC2CCCN2C(=O)c2ccc3[nH]cnc3c2)c1 +CC1CN(S(=O)(=O)NC(C)C2CCCO2)CC(C)O1 +CCNS(=O)(=O)c1cc(C(=O)NC(C)CC)ccc1OC +CN(C)S(=O)(=O)c1cc2c(cc1Br)OCCO2 +CCCOc1ccc(C(=O)NCC2C(=O)N=C(C)C=C2C)cc1 +CCSc1nnc(SCc2c(C)noc2C)s1 +CC1CCCC(NC(=O)C2CCCN2C(=O)OC(C)(C)C)C1 +O=C(c1ccco1)N1CCC(n2c(-c3ccoc3)nc3cccnc32)C1 +CC(NC(=O)c1cccs1)C(=O)OC(C)c1cc(F)ccc1F +COc1ccc(-c2noc(-c3cccc(N)c3)n2)c(OC)c1OC +Cc1sc(NC(=O)c2c(Cl)cnn2C)c(C(N)=O)c1C +CCCNS(=O)(=O)c1cc2c3c(c1)c(C)cc(=O)n3CC2 +COC(=O)CNC(=O)c1nn(-c2ccc(F)cc2)c2c1CCC2 +CN(Cc1cc(F)c(F)c(F)c1)C(=O)Nc1ccncc1F +CN(C)C(=O)N1CCCn2nc(CNc3ccc(C#N)cn3)cc2C1 +CCCC(=O)N1CCCC1C(=O)NC1CC1c1ccccc1OC +O=C(CSc1nnc(NC2CC2)s1)Nc1ccccc1 +CCc1noc(CN(C)Cc2sc(N(C)C)nc2C)n1 +Cn1c(CCNC(=O)c2cccc3nscc23)nc2ccccc21 +CCC(OC1CCCC1)C(=O)OC(C)c1cccnc1 +CC(=O)c1cccc(OC(C)C(=O)Nc2ccc(F)c(F)c2F)c1 +CN(C(=O)c1ccc2[nH]ccc2n1)c1ccccc1 +CCc1ccccc1NS(=O)(=O)c1cc2c(cc1C)NC(=O)CO2 +COCCOCC(=O)Nc1cccc(-c2ccc(=O)[nH]n2)c1 +CCN(CCNC(=O)c1ccc2c(c1)COC2)c1ccccc1C +Cc1c(C(=O)N(C)Cc2ccc3c(c2)OCO3)[nH]c2c1C(=O)CCC2 +Cc1cccc(C(=O)Nc2cc(Cl)ccc2-n2cncn2)c1C +O=C(COc1ccc(Cl)cc1Br)N(CCO)C1CC1 +COC(=O)N1CCC(CNC(=O)c2cc(C)ccc2C)CC1 +CCOc1ccccc1OC(=O)c1ccc2c(c1)OCCO2 +CC1CCC(Oc2cc(CNC(=O)c3ccc[nH]3)ccn2)CC1 +N#Cc1ccc(OCC(=O)N2CCN(c3ccccc3F)CC2)cc1 +Cc1cc(=O)c2cccc(F)c2n1CC(=O)Nc1cc(F)cc(F)c1 +Cn1ccnc1C(NC(=O)N1CCOCC1)c1ccc(Cl)cc1 +Cc1ccc2cc(C(=O)NC(C)c3c(C)noc3C)c(C)nc2c1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)NC(C)(C)C)c(C)c1 +O=C(NC1CCN(c2ccc(Cl)cc2)C1)c1ccncc1 +CCOc1ccc(CC(=O)Nc2nnc(-c3ccnn3C)o2)cc1 +Cc1ccccc1C1CC1C(=O)N1CCN(Cc2cccs2)CC1 +CCN(Cc1cc(Br)ccc1F)C(=O)c1cc(C)n[nH]1 +COC(=O)CSc1nc2c(c(=O)n1C)SC(C)C2 +CSc1nccc(-c2ccnc3c2ccn3C)n1 +Cc1ocnc1CNC(=O)Nc1cccc(-c2ncco2)c1 +COc1ccc2ccn(CC(=O)NCc3ccccc3)c(=O)c2c1 +O=C(CC1CCCCC1)OCCNC(=O)c1ccncc1 +Cc1ccc(NC(=O)NCCOc2nc(N)nc(N(C)C)n2)cc1 +CN(C(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1)C1CCCC1 +COCCN1CCN(S(=O)(=O)c2c(C)noc2C)CC1 +CCCNc1ccc(C(F)(F)F)cc1NC(=O)CNC(=O)NC +CC(NC(=O)c1cccc2cccnc12)c1ccc(F)cc1F +Cc1ncc(C(C)NC(C)c2ccc(S(C)(=O)=O)c(F)c2)s1 +COCCn1c(=O)c2c(ncn2C(C)C)n(-c2ccccc2C)c1=O +COc1ccc(C(=O)CNc2nonc2C)cc1OC +COCc1cccc(CNC(=O)N2CCC3(CC2)OCCO3)c1 +N#CCCCC(=O)c1cccc(Br)c1 +CCc1ccccc1OCC(=O)Nc1cnccc1C +Cc1ccc(NC(=O)Nc2ccc(NC(=O)C3CCCO3)cc2)cc1 +Cc1ccc(Nc2nc(CN3CCNC(=O)C3)cs2)cc1 +CC1Oc2ccccc2OC1C(=O)Nc1cc(N2CCCC2)ncn1 +C=CCNC(=O)COC(=O)c1ccc(Br)cc1 +CC(CC(=O)OCCn1nc2ccccn2c1=O)c1ccccc1 +COc1ccc(Br)cc1NC(=O)c1ccc(N)cc1 +CC(C)N1C(=O)C(Cc2ccccc2)Oc2ccc(N)cc21 +O=C(NC1CC1)c1ccc(NC(=O)N2CCc3sccc3C2)cc1 +COCCOCC(=O)Nc1ccnn1-c1cccc(Cl)c1 +CCc1cnc(NCc2cc(C(C)(C)C)n[nH]2)nc1 +CC(CO)(NC(=O)Nc1ccc(F)cc1Cl)C1CC1 +COc1ccc(CCNC(=O)c2cnn3ccc(C)cc23)cc1OC +Cn1cc(CCOC(=O)c2c(F)cc(Br)cc2F)cn1 +COc1ccc(CN2CCN(C(=O)NC(C)(C)C)CC2)cn1 +CCC(NC(=O)c1occc1C)c1ccc(S(C)(=O)=O)cc1 +NC(=O)CC1CCN(C(=O)NCc2ccc(F)c(Cl)c2)CC1 +CCC(NC(=O)NCc1ncn(C)n1)c1ccc2c(c1)OCCO2 +CCOC(=O)c1sc(-c2ccccc2)cc1NC(=O)C1CCCO1 +CCc1noc(CC)c1CNC(=O)C1CCN(C(=O)N(C)C)CC1 +COC1(C)CN(C(=O)Nc2ccc(C)c(-c3nc(C)co3)c2)C1 +CCc1cc(NCC(=O)NCc2ccco2)nc(-c2ccccn2)n1 +Cc1ccc(CNc2cc(OCC(C)C)ncn2)cc1 +CCOC(=O)Cn1ccc2c(=O)n(C)c(=O)n(C)c21 +CC(C)N(C)S(=O)(=O)c1cccc(C#CCCO)c1 +COc1ccc(NC(=O)Nc2ccc(C(N)=O)cc2)c(C)c1 +O=C(CNC(=O)c1cc2c(s1)CCCC2)NCCc1cccnc1 +N#Cc1cnn(-c2cc(Cl)cc(Cl)c2)c1N +O=C(CCCc1ccccn1)NCCc1c(F)cccc1Cl +CC(C)(C)OC(=O)N1CCCC(Oc2ncccc2C#N)C1 +CCC(=O)N1CCc2cc(CNC(=O)c3ccccc3Cl)ccc21 +Cc1ccc(S(=O)(=O)N(C)Cc2ccc(C)o2)c(Cl)c1 +CC(C(=O)N(Cc1ccccc1)CC1CCCO1)c1cccs1 +CC(=O)Oc1nn(-c2ccccc2)cc1Br +COC(=O)c1ccc(C)c(OCC(=O)NC(C)C)c1 +CCN(CCCNC(=O)N1CCC(C)CC1C)S(C)(=O)=O +N#Cc1nc(-c2ccco2)oc1N1CCC(C(=O)NCCO)CC1 +c1ccc(C(Cn2ccnc2)n2ccnc2-c2ccccn2)cc1 +NS(=O)(=O)c1cccc(NC(=O)CCC(=O)c2cccs2)c1 +CCOc1cc(C(=O)Nc2nc(C)c(C)s2)nn1-c1ccccc1 +CS(=O)(=O)NCCc1ccc(-c2csc(NC3CC3)n2)s1 +O=C(COC(=O)c1ccccc1Br)NC1CC1 +Cc1cc(Cl)ccc1NC(=O)CSc1n[nH]c(=O)[nH]c1=O +Cc1ccc(NC(=O)CCNS(C)(=O)=O)c2[nH]ncc12 +CCN1Cc2ccccc2CC1C(=O)N(C)Cc1[nH]nc2c1CCC2 +CCc1ccccc1OCC(=O)NCc1cccc(OC)c1 +COc1cc(S(=O)(=O)CCO)c(OC)cc1NC(C)=O +COc1cc(NC(=O)C(C)Sc2nncs2)cc(OC)c1 +NC(=O)c1nn(-c2nc3ccccc3[nH]2)c2c1CNCC2 +CN(C)c1cc(C(=O)N(C)C2CCc3ccccc3C2)ccn1 +CCn1cc(C#N)c(=O)n(CC(=O)OC(C)C)c1=O +C=CCN(Cc1cccc(C#N)c1)Cc1sc(N(C)C)nc1C +CCOCC(=O)Nc1ccc2nc(N3CCOCC3)sc2c1 +CC(=O)c1cc(C(=O)N(Cc2ccc(C)s2)C(C)C)n(C)c1 +Nc1cc(F)ccc1NC(=O)CCn1cc(Cl)cn1 +CC(C)CC(=O)Nc1cnc(-c2ccccc2)nc1 +COC(=O)c1cnc(-c2ccccc2Cl)s1 +OCCCSc1ncnc2c1cnn2-c1ccccc1 +CCOC(=O)CN1CCN(C(=O)COc2ccc(F)cc2)CC1 +O=C(Cn1ncc(N2CCCC2)c(Cl)c1=O)Nc1ccccc1 +Cc1ccccc1SCC(=O)NCc1ccc2c(c1)OCCO2 +CN(C)C(=O)c1cccc(S(=O)(=O)NCc2ccc(F)cc2)c1 +CC(C)C(C)NC(=O)CSc1nncn1-c1cccc(Cl)c1 +COC(=O)Nc1ccccc1C(=O)N(C)CC(C)c1ccccc1 +COC(=O)c1ccc(Cl)c(CN2CCN(c3cnn(C)c3)CC2)c1 +CC(=O)NCc1ccc(C(=O)OCc2ccoc2C)cc1 +NS(=O)(=O)c1cccc(NS(=O)(=O)c2c(F)cccc2F)c1 +Cc1c(C(=O)N2CCOCC2)c(CC(C)C)nn1-c1ccccc1 +COC(=O)c1csc(C2OC(CO)C(O)C2O)n1 +Cc1ccc(CN2CCN(C(=O)CC(F)(F)F)CC2)o1 +O=C(NCCCO)Nc1cccc(Cl)c1Oc1cccnc1 +COc1ccc(CO)c(NC(=O)c2ccc(F)cc2)c1 +Cc1noc2nc(-c3cccs3)cc(C(=O)Nc3nncs3)c12 +COc1ccccc1C(O)CCC(=O)NC1CCCCC1 +O=C(CN1CCCCC1=O)Nc1nc(-c2ccccc2Cl)cs1 +Cc1ccc(CN(C(=O)OC(C)(C)C)S(C)(=O)=O)cc1 +CC(C)CN1CC(C(=O)N(C)CC2(CO)CCOCC2)CC1=O +NC(=O)c1nc(CNC(=O)Nc2ccc(C3CCCCC3)cc2)no1 +CCCC1CCCN(C(=O)CN(CCc2ccccc2)C(C)=O)C1 +O=C(Nc1ccc(F)cc1F)c1cccc(OCC(F)F)n1 +CCN(CC)c1nc2c(c(=O)n(C)c(=O)n2C)n1C(C)C +CCC(=O)N(C)Cc1cc(-c2cccc(OC)c2)on1 +CCN(Cc1ccccc1Cl)C(=O)CNC(=O)NC +O=C(CCSc1ccccc1Br)Nc1nccs1 +COC(=O)c1cncn1C(C)c1cccc2ccccc12 +Cc1nc(-c2ccccn2)sc1C(=O)Nc1ccccc1F +Cc1noc(C2CCCCN2C(=O)C2CCCC2)n1 +FC(F)(F)Oc1cccc2c1C(CC1CC1)NCC2 +CN(C1CC1)S(=O)(=O)c1ccc(-c2ccccc2)cc1 +NC(=O)c1ccc(OCC(=O)Nc2ccc3c(c2)OCCCO3)cc1 +Cc1cc(C(=O)NC(C)c2ccncn2)c2ccc(C)c(C)c2n1 +O=C1CN(C(=O)Nc2ccc(Oc3cccc(F)c3)cc2)CCN1 +CCc1onc(C)c1NC(=O)c1cccc(OCC2CCCO2)c1 +Cc1ccc(N2Cc3ccc(N)cc3C2=O)c(C)c1 +Cc1ccc(C(=O)CCC(=O)Nc2nc(C(F)(F)F)cs2)cc1 +COc1c(C)cnc(CN(C)C(=O)c2ccccc2F)c1C +Clc1cnc(N2CCN(c3ncccn3)CC2)c(Cl)c1 +Clc1cc(Br)cnc1N1CCCC1 +CC1CN(C)c2ccccc2CN1C(=O)C1CCC(=O)NC1 +CC(=O)N1CCc2cc(NC(C)C(=O)Nc3ccc(C#N)cc3)ccc21 +Cc1ccc(C2NCCc3ccc4c(c32)OCO4)cn1 +Cc1cccc(NCC(=O)N(C)C(C)c2ccc(F)cc2)c1C(N)=O +CC1CN(CCO)c2cc(Cl)c(Cl)cc2N1 +COCCCNC(=O)C(C)n1nc(-c2ccco2)cc(N)c1=O +CCOc1ncccc1C(=O)Nc1ccc2c(c1)COC2 +Cc1[nH]c2ccccc2c1C(=O)COc1cccc(S(C)(=O)=O)c1 +COC(=O)C(CO)Nc1nccc(C(F)(F)F)n1 +CC(C)CCNC(=O)C1CCCCN1C(=O)c1ccoc1 +Cc1ccc2c(c1)N(CCC(=O)NC1CC1)C(=O)C(C)O2 +COC(=O)C1CCCCN1Cc1cn(-c2ccccc2)nc1C +Cc1cc(C)c2ncn(CC3CCC(=O)N3C)c(=O)c2c1 +CNc1snc(C)c1C(=O)N1CCC(c2ccccc2)C1 +C=CCn1c(SCC(=O)N(C)C)nc2sccc2c1=O +COc1ccc(Br)c(CC(=O)NCc2ncc[nH]2)c1 +Cc1ccc(F)cc1S(=O)(=O)NCc1ccc(NC(N)=O)cc1 +CCC(C)c1ccc(NC(=O)c2ccc(OCC(N)=O)cc2)cc1 +NC(=O)C1CCN(C(=O)CCn2ccc3ccc(F)cc32)CC1 +CC(NS(=O)(=O)c1cccc(Cl)c1Cl)c1cccnc1 +Cc1ccc(CS(=O)(=O)N2CCC3(CC2)CNC(=O)C3)cc1 +Cc1cc(OCC(=O)NCCc2ccc(S(N)(=O)=O)cc2)no1 +COc1ccccc1OCC(=O)OC1CCCC(OC)C1 +CCOc1ccccc1CCC(=O)NCC(N)=O +CCn1nc(C(=O)NCc2ccc(Cl)cc2)c2ccccc2c1=O +CC1CCC(C)N(C(=O)Nc2ccccc2Cn2cncn2)C1 +COc1cccc(C(=O)CN2CCc3ccccc3C2)c1 +O=C1Cc2cc(NS(=O)(=O)Cc3ccccc3)cc3c2N1CCC3 +COc1ccc(C)cc1NC(=O)c1ccc(Cn2cccn2)cc1 +O=C(CSc1ccccc1F)Nc1ccc(Br)cn1 +COC(=O)c1ccc(Cn2c(C)nc3cc(F)ccc32)cc1 +Cc1cnn(CC(=O)Nc2cccc(C(=O)N(C)C)c2)c1 +CCc1c(C(=O)Nc2ccc(C(C)=O)c(C)c2)cnn1-c1ccccn1 +Cc1ccccc1C(=O)Nc1ccc2c(c1)C(=O)N(C)C1=NCCN12 +Cc1[nH]c2nc(-c3ccncc3)nn2c(=O)c1CCC#N +O=C(Nc1nnc2ccccn12)NC(CO)c1ccccc1 +CCCC(=O)NC1CCCN(c2cncc(C)n2)C1 +Cc1cc(NC(=O)CNc2ccc3c4c(cccc24)CC3)on1 +CCOC(=O)c1nc(C(=O)NC(C)C)n2ccccc12 +N#Cc1ccc(OC(F)F)c(NC(=O)COc2ccccc2C#N)c1 +CCOC1CC1C(=O)NC1CC1c1ccccc1Br +CCN(CC)C(=O)C(C)S(=O)(=O)c1ccccc1C +CCNC(=O)Nc1ccc(OCC(=O)NCc2cccs2)nc1 +Cc1ccc(CNC(=O)NCC(=O)Nc2ccc(F)c(C#N)c2)cc1 +Cc1ncc(Cl)c(C(=O)NCc2ccnc(OC(C)(C)C)c2)n1 +CCc1onc(C)c1NC(=O)COc1ccc(F)cc1 +Cc1ccc(C(C)NC(=O)CNS(=O)(=O)c2cnn(C)c2)o1 +CNC(=O)CC1C(=O)NCCN1Cc1ccc(Cl)c(F)c1 +O=C(Nc1cn[nH]c1)c1ccc(F)c(S(=O)(=O)NC2CC2)c1 +CCCCS(=O)(=O)NC(C)C(=O)N1CCOCC1 +COc1ccc(CCC(=O)NCc2cnn(-c3ccccc3)c2)cc1 +N#Cc1ccc(NC(=O)CSc2ccc(C#N)cc2)cc1 +CCCc1nnc(N2CCN(c3cccc(OC)c3)C(=O)C2)o1 +O=C(NCCNC(=O)c1ccc(-n2cncn2)nc1)c1ccccc1 +CC1CN(C(=O)Nc2ccc3c(c2)CCO3)CCN1CC(F)(F)F +CC(=O)Oc1cccc(C(=O)c2c(F)c(F)c(F)c(F)c2F)c1 +CCn1ncc(-c2cc(F)ccc2OC)c(CO)c1=O +CCCN(CCC)C(=O)c1cc(S(=O)(=O)N2CCCCC2)c[nH]1 +Cc1cccn2cc(CSc3ncnc4nc[nH]c34)nc12 +COCC(O)CN(C)C(=O)Nc1cc(OC)ccc1F +CCCN(Cc1ccc(C#N)cc1)C(=O)CC1OC(=O)c2ccccc21 +COc1ccc2c(c1)c1c(n2C(C)=O)C(OC(C)=O)=NCC1 +Cc1ccc(NC(=O)CCCOc2cccc(F)c2)nc1 +COCCCSc1nnc(-c2c[nH]c3ccccc23)n1C1CC1 +CCC(NC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3)C(C)C +CCOc1ncccc1C(=O)Nc1ccc(Br)cn1 +Cc1cc(CSc2ccccc2C(=O)NCCCO)on1 +Cc1ccccc1CC(=O)Nc1nc2cc3c(cc2s1)OCCO3 +CC(=O)NCCNC(=O)C(C)(C)c1ccc2c(c1)OCCO2 +CC(C)(CO)CNc1ccnc(Cc2ccccc2)n1 +COc1ccc(N)cc1CNS(=O)(=O)c1cccc(C)c1 +COCCC1CCN(C(=O)c2ccc(C)nc2)CC1 +CN(Cc1ccccc1-n1cccn1)C(=O)c1cc(C2CC2)n[nH]1 +CCOC(=O)n1c(=O)n(C)c2ccc(Br)cc21 +CSc1nn(-c2cccc(C#N)c2)c(N)c1C#N +COc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1Cl +NC(=O)c1cnc(NC(=O)c2cccc(-n3cnnn3)c2)s1 +Cc1ccc(CNC(=O)COC(=O)c2ccc3c(c2)OCO3)cc1C +COc1cc(C(=O)Nc2c(C)cc(C)nc2C)cc(Cl)c1OC +CC(NC(=O)c1cc(-c2cccn2C)n[nH]1)c1ccccc1 +c1cc(CNc2ccc(-c3nnc4n3CCCC4)cc2)c2[nH]ncc2c1 +O=C(COC(=O)C1CC1)Nc1ccc(Cl)cn1 +CC(NS(=O)(=O)c1cc2ccccc2o1)C(=O)Nc1ccccc1 +COc1ccc(NC(=O)Cc2noc3ccc(N)cc23)cc1 +Cc1c(Cl)cccc1S(=O)(=O)N(C)CCC(F)(F)F +COCc1cc(CNc2cnn(C)c2C)ccc1OC +CCCn1cc(NC(=O)CN(C)C(C)=O)ccc1=O +Cc1cccc(Cc2nc(C)c(CC(=O)n3ccnc3)c(C)n2)c1 +Cn1nnc2cc(C(=O)Nc3ccc(F)cc3)ccc21 +Fc1ccc2c(c1)C(c1cc(-c3cccs3)n[nH]1)NCC2 +COc1ccc(OC)c(NC(=O)Cn2ccc(=O)[nH]c2=O)c1 +COC(=O)c1ccc2c(c1)CCN2C(=O)OC(C)(C)C +CNC(=O)Nc1ccc(Br)cc1Cl +CCOC(=O)CN(C(=O)c1ccc2ccccc2c1)C(C)C +Cn1ncc(N2CCC(Cc3ccccc3)CC2)c(Cl)c1=O +CCOc1ccc(C#N)cc1NC(=O)c1cccc(NC(=O)OC)c1 +O=S(=O)(NCCc1cccs1)c1ccc2c(c1)CCC2 +CCCN(CC(=O)NC)C(=O)c1cc(F)ccc1N +Cc1nn(C)cc1C(=O)NC(C)c1c(C)noc1C +CCN(CC(=O)OC)C(=O)CSc1ccc(F)cc1 +CCN(C(=O)C(C)Oc1ccc(S(C)(=O)=O)cc1)c1ccccc1 +Nc1cccc2ccnc(C(=O)Nc3cccc4cccnc34)c12 +CC(Nc1cccc(CO)c1)C(=O)Nc1ccc2c(c1)OCO2 +Cc1nnc(NC(=O)Cn2nc(-n3cccn3)ccc2=O)s1 +O=C(CCNC(=O)c1ccc2ccccc2c1)Nc1ccccc1O +Cc1csc(NC(=O)Cc2noc3ccc(N)cc23)n1 +Cc1ccc(S(=O)(=O)N2CCN(C(C)C#N)CC2)cc1C +O=C(NCCCN1CCOCC1)c1ccc2[nH]ccc2c1 +COc1ccc(CNC(=O)c2ccc(OC)cc2OC)c(OC)c1 +Cc1ccn2c(=NC(=O)c3ccc(C#N)cn3)[nH]nc2c1 +O=C1CCCN1CC1CCCN(c2cnccn2)C1 +Nc1c(C(N)C(F)(F)F)cc(Cl)cc1C(F)(F)F +COc1ccccc1NC(=O)c1ccc(N2CCCC2)nn1 +CC1C(=O)Nc2c(Cl)cc(C(O)c3ccccc3)cc21 +O=C(CCSc1ccccc1)Nc1ccc2c(c1)OCO2 +CCOc1cccc(C(C#N)N(C)S(=O)(=O)CC)c1 +CCOCCCNC(=O)c1cc(C)nc(N2CCCC2)n1 +Cc1nn(CCOc2ccccc2)c(=O)n1-c1ccccc1F +CC(CC(=O)Nc1ccc(NC(=O)C2CC2)nc1)C(C)(C)C +COc1ccc(F)cc1NC(=O)c1cncn1-c1ccccc1 +CCOCc1ccccc1NCc1cccc2c1OCO2 +CCc1n[nH]c(SC(C(=O)NC(C)c2ccccc2)C(C)C)n1 +O=C(CCc1ccccc1)N1CCN(CCO)CC1 +Cc1cc(C)n(-c2ccc(NCc3ccccc3C#N)cc2F)n1 +COc1cccc2c(=O)c(C(=O)NCCO)c[nH]c12 +CCCS(=O)(=O)Nc1cccc(-c2cn3ccc(C)cc3n2)c1 +Cc1ccc2c(CC(=O)N(CCO)Cc3ccccc3)coc2c1C +CCn1nc(C)c(CCN(C)S(=O)(=O)N(C)C)c1C +Cc1noc(CCC(=O)NCC(C)c2cccs2)n1 +CCOc1ccc(C(=O)NCCNC(=O)c2nonc2N)cc1 +O=C(NC1CCCC1)C1c2cccn2CC(=O)N1Cc1cccnc1 +COc1cccc2c1C(C(=O)N1CCCC1)CC2=O +Cc1cccc(CN(C(=O)NCCNS(C)(=O)=O)C2CC2)c1 +COCc1nn2c(N)c(C#N)nnc2c1-c1ccc(OC)c(OC)c1 +COc1cccc2c(=O)n(CC(=O)Nc3ccc(C)cc3)ccc12 +CS(=O)(=O)NCc1nnc2n1CCN(CC1CC1)C2 +COCC(C)NC(=O)N(Cc1ccccc1)CC1CCC1 +CCc1ccc(-c2ccc(C(=O)N3CCCCC3)c(N)n2)cc1 +CCc1nc(CC(=O)Oc2cccc(C(F)(F)F)c2)cs1 +O=C(Cn1nnc(-c2ccccc2)n1)Nc1nnc(C2CCCO2)o1 +COc1ccccc1-c1nc2ccc(Cl)cn2c1N +COc1cc(F)ccc1NC(=O)NCC(C)(C)c1ccncc1 +Cc1cc(C(=O)Nc2c(F)cc(F)cc2Br)no1 +Cc1nc2cc(NC(=O)C3CC3(Cl)Cl)ccc2o1 +O=C(Nc1ccc(OC2CCCC2)cc1)C1CCCO1 +Nc1nonc1CC(=O)N1CCCc2ccccc21 +CNS(=O)(=O)c1cccc(C(=O)N(CC2CCOC2)C2CC2)c1 +C#Cc1cccc(NC(=O)c2cnc3[nH]nc(C)c3c2)c1 +CC(=O)Nc1ccc(C(=O)OCC(=O)Nc2ccc(F)c(F)c2)cc1 +CC(=O)Nc1ccc(O)c(C(=O)NC2(C#N)CCCCC2)c1 +Cc1cccc(OCC(O)CSc2nc(C)cc(N)n2)c1 +CCC(C)(O)C#CCN1CCCCC1c1cccnc1 +COc1ccc(Br)c(NC(=O)N(C)Cc2ccco2)c1 +CCn1ccc(CN(C)S(=O)(=O)c2ccc(C(C)C)cc2)n1 +Cc1ccc(C(C)NC(=O)NCCN2CCOCC2)cc1 +O=C(OCCc1cccnc1)c1ccc(-c2cnco2)cc1 +O=C(CCCc1nc(-c2ccccc2)no1)NCC(=O)N1CCCC1 +COCCOc1ccc(C(=O)Nc2cccc(C(=O)N(C)C)c2)cc1 +Cn1cccc1C(=O)N1CCc2c(CNS(C)(=O)=O)cncc2C1 +Cn1cc(NC(=O)N2CCc3sccc3C2)cn1 +O=C(CNC(=O)NC(CN1CCCC1=O)c1ccccc1)NC1CC1 +CCN(CC)C(=O)c1ccccc1SCc1ccc(C#N)cc1 +O=C(NCc1cccc(OC(F)(F)F)c1)c1cc2cccnn2n1 +CC(C)C1(O)CN(S(=O)(=O)N(C)Cc2ccccc2)CC1C +Cn1cc(C(=O)Nc2ccc3c(c2)COC3)ccc1=O +CCOC(=O)c1c(C)csc1NC(=O)COc1ccccc1 +Cc1cc(NC(=O)CCCNC(=O)NC2CCCCC2)ccn1 +Cc1nn(C)c(C)c1CC(=O)Nc1ccc2oc(C(C)C)nc2c1 +c1ccn2c(CSc3nnnn3C3CCOCC3)cnc2c1 +O=C(CNC(=O)C1(c2ccccc2)CC1)Nc1ccc(F)c(F)c1 +Cc1cc(C)cc(NCC(=O)N2CCC3(CC2)OCCO3)c1 +CCCC(=O)Nc1ccc(NC(=O)CCC)c(OC)c1 +CCC(=O)c1cccc(NC(=O)c2cnn(C(C)CC)c2C2CC2)c1 +Cc1ccc(C(=O)OC(C)c2nc3sc(C)c(C)c3c(=O)[nH]2)cn1 +COc1cccc(C(=O)Nc2nc(C(F)(F)F)cs2)c1F +COCc1nnc(NC(=O)c2cc3cc(F)ccc3n2C)s1 +CCOC(C)c1noc(CN2CCOc3ccc(F)cc32)n1 +CC(C)Oc1ccc(Nc2ccc(N)cc2N)cc1 +COc1ccc2nnc(CCCC(=O)Nc3nc(C)cs3)n2n1 +COc1c(Cl)cc2c(c1OC)C(CC(C)(C)C)NCC2 +O=c1[nH]c2ccccc2c(=O)n1Cc1ccccc1F +CCN(CC1CCCO1)S(=O)(=O)c1ccc(C)c(C(N)=O)c1 +COc1ccc(-c2nnc(SCc3nnnn3C3CC3)o2)cc1 +N#CC1(c2ccccc2)CCCN1C(=O)c1ccco1 +CCCCc1nnc(SCC(=O)N2CCOCC2)n1N +CNc1ncc(S(=O)(=O)Nc2ccccc2)cc1Cl +COc1cc(C(=O)N2CCC2)ccc1OCc1cscn1 +CN(C)S(=O)(=O)N(CCCO)CC(C)(C)C +CCn1nc(C(=O)Nc2nnc(-c3cccc(OC)c3)o2)cc1C +Cc1ccc(C(=O)CCCC(=O)N2CCC(C)CC2)cc1 +COCC(NC(=O)c1csc(-c2ccc(C(C)C)cc2)n1)C(N)=O +O=S(=O)(Nc1cccnc1)c1ccc(Cl)c(Cl)c1 +COCCCOc1ccccc1NC(=O)c1sccc1C +O=C(CCc1ccccc1)NC1CCN(CC(F)(F)F)C1=O +CCN(C(=O)C1CC(=O)N(c2ccc3c(c2)OCO3)C1)C(C)C(C)C +C#Cc1cccc(N(CC)C(=O)c2ccc(OC)c(-n3cnnn3)c2)c1 +CC(C)Oc1ccccc1CS(=O)(=O)c1ccccn1 +Cc1cc(C(=O)N2CCN(C(=O)c3cnn4ccccc34)CC2)no1 +Cc1cc(NC(=O)COC(=O)Cc2ccc(Cl)cc2)n(C)n1 +Nc1cccc(C(=O)OCCOCC(F)(F)F)c1 +O=C1CCc2cc(NC(=O)c3cnc4ccccc4n3)ccc2N1 +Cc1cc(C)n2nc(CC(=O)Nc3ccc(N(C)C)nc3)nc2n1 +CCn1cc(CC(=O)c2ccc(F)c(Cl)c2)cn1 +C#CCNC(=O)CS(=O)(=O)c1ccc(Cl)cc1 +CCOC(=O)c1ccc(NC(=O)c2cc(C)no2)cc1 +Cc1cc(CNC(=O)NCC2CC2C)ccc1F +COc1ccc(-c2cc3cccnc3n2Cc2ccncc2)cc1 +O=S(=O)(c1cccs1)N1CCCCC1CCO +O=S(=O)(c1ccc(F)cc1Cl)N1CCCn2ncnc21 +CN(C(=O)c1ccc(S(C)(=O)=O)cc1)c1ccc(F)c(F)c1 +COCCN(Cc1cccs1)C(=O)C1Cc2ccccc2C(=O)O1 +O=S(=O)(NCC1(O)CCCC1)c1ccc(F)cc1F +CC(Sc1nnc(CO)n1C1CC1)C(=O)N1CCc2ccccc21 +CC(C)OCC1CCC2C1OCCN2Cc1ccsc1 +CC(Nc1ccc(SC(F)F)cc1)c1cnn(C)c1 +C=CCN(Cc1ccccc1)C(=O)NCc1nnc2ccccn12 +CCNC(=O)N1CCN(C(C)C(=O)NCCCOC)CC1 +CCc1nn2c(CO)c(-c3ccc(OC)c(OC)c3)nc2s1 +CC1CCCC1NC(=O)NCC1CN2CCCCC2CO1 +CC(=O)N1CCN(Cc2ccccc2)CC1c1nc2ccccc2[nH]1 +Cc1ccc(CNC(=O)N(C)Cc2cnn(C)c2)s1 +CN(C)c1cccc(C(=O)OCC(=O)Nc2ccc(F)cc2)c1 +Cc1cccnc1NC(=O)CCN1C(=O)C(C)Oc2ccccc21 +CCNC(=O)N(Cc1ccc2c(c1)OCO2)Cc1ccco1 +CCn1nnnc1SC(C)C(=O)NC(C)(C)C +COc1cccc2c(C)cc(=O)n(C(C)C(C)=O)c12 +COc1ccc2cc(C)c(SCC(=O)N3CCOCC3)nc2c1 +C#CC(C)OC(=O)c1cc(S(=O)(=O)N(C)C)c(C)o1 +Cc1cccc(NS(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O)c1C +C=CCNC(=O)c1ccccc1NC(=O)c1cccc(-n2cnnn2)c1 +COCc1c(C(=O)Nc2nc[nH]n2)sc2cccc(F)c12 +CC(=O)N(c1nnc(SCc2ccc(F)c(F)c2)s1)C1CC1 +O=C(NCC1CC1)C1CCOC2CCN(c3ncccn3)CC21 +CCOC(=O)c1cnn(C2CCCN(Cc3cncs3)C2)c1 +COc1cc(C(C)C)ccc1-c1nn(C)c(C)c1N +Oc1ccc(C(O)CNCc2cccc(F)c2)cc1 +O=C(NC1CCCCCC1)c1cc(F)ccc1-n1cnnn1 +COc1c2ccc(C(=O)NCc3ccc(Cl)cc3)cc2nn1C +Cc1nc2ccc(C(=O)Nn3cnc4ccccc43)cc2nc1C +CC(C)c1nc(NCCO)c2nnn(Cc3ccccc3)c2n1 +Cc1ccc(C(=O)NCCNC(=O)NC(C)C(C)C)cc1F +Cc1cc2c(=O)n(Cc3ncc(-c4cccs4)o3)cnc2s1 +CCCCNC(=O)c1snc(-c2ccc(C)cc2)c1N +COCCCNc1ccc(S(C)(=O)=O)cc1F +CCn1cc(C(=O)Nc2ccncc2)c(=O)c2cc(F)ccc21 +Cc1ccc2ncc(C(=O)NC3CCCc4c3cnn4C)c(=O)n2c1 +CCCc1nn(CC(=O)NC(C)C)c(=O)c2cc3ccsc3n12 +Cc1ccc(OCc2nc(CSc3nnc(C)n3N)cs2)cc1 +Cc1ccccc1CN(C)C(=O)c1cccc(-n2cnnn2)c1 +COc1ccc(S(=O)(=O)N(C)Cc2cccnc2)cc1F +O=C(C1CC1c1ccco1)N1CCN(Cc2ccccc2)CC1 +CNS(=O)(=O)c1cc(NCCC(C)(C)C)ccc1C +Cc1nc(C2CCCN(C(=O)c3cnn(C)c3)C2)cc(=O)[nH]1 +CC(NC(=O)C1CC1c1cccc(Br)c1)c1cccnc1 +O=C(CC1CCCC1)N1CCN(C(=O)c2ccccc2)C1 +CC(C)CCN(C)C(=O)CCNC(=O)c1ccco1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1 +CCc1cc(C(=O)NCCNC(=O)C2CC2)sc1C +O=C(NC(CN1CCCCCC1=O)c1ccccc1)C1CCC1 +c1ccc(Cc2noc(CSc3nnnn3C3CC3)n2)cc1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccc(C)cc2Cl)cc1 +CN(C)C(=O)CCCC(=O)N1CCC(c2c[nH]c3ccccc23)CC1 +Cc1[nH]c2ncnn2c(=O)c1CCOC(=O)c1ccccc1F +Cc1ccc(C(=O)Nc2ccc(C(=O)NC3CCCCC3)cc2)cn1 +C=CCc1cc(CNc2ccc(S(N)(=O)=O)cc2)cc(OC)c1O +CCCn1c(C)nnc1SC1CCN(c2ccccc2)C1=O +Nc1ccc(S(=O)(=O)NCc2ccccc2)cc1 +CNC(=O)CNC(=O)c1occc1CS(=O)(=O)c1ccccc1 +CNc1ncc(-c2nnnn2-c2ccccc2)c(-c2cccs2)n1 +CCOc1ccc(F)c(C(=O)Nc2cc(C)cnc2OC)c1F +COCCNC(=O)N(C)C1CCN(c2ccccc2)C1=O +CCC(C(=O)NCCc1ccccc1)N1C(=O)CCn2nc(C)cc21 +Cc1ccc(-n2cc(C(=O)NCc3ccccc3)nn2)cc1 +Cc1nc(Cc2noc(C=Cc3nc4ccccc4o3)n2)no1 +COc1ccc(C(=O)NCCC(=O)N2CCCCC2)c(OC)c1 +COc1ccc(C(=O)NCc2cccc(C#N)c2)cc1Br +Cc1ccc2cnn(CCC(=O)Nc3c(C)noc3C)c2c1 +CNC(=O)CN(C)c1ncc(C(F)(F)F)cc1Cl +COc1ccc(Cc2nnc(SC)n(N)c2=O)c(OC)c1 +C=CCOC(=O)Cc1csc(NC(=O)c2ccco2)n1 +COCCCCCNC(=O)c1ccc(C)nc1C +N#Cc1cccc(NC(=O)Cc2cccc(Br)c2)c1 +CC(C)Sc1nc(N)c(S(=O)(=O)c2ccccc2)s1 +CSc1cccc(NCc2ccccc2OCC(=O)N(C)C)c1 +COCc1c(C(=O)NCCO)nnn1-c1ccc(OC)cc1 +Cn1cc(CCC(=O)NCc2cn(-c3ccccc3)nn2)cn1 +Cc1ccc(NC2(C(=O)NC(C)c3ncn[nH]3)CCCC2)cc1 +CC1CC(Sc2cc(C(=O)NC3CC3)c3ccccc3n2)C(=O)O1 +CC(=O)Nc1ccc(N2CC(C(=O)Nc3nncs3)CC2=O)cc1 +COc1ccc(NC(=O)C2CCCN2C(=O)OCC(F)(F)F)cn1 +Cc1nnc(C)c2c(C)n(Cc3ccccc3)c(C)c12 +CCn1c(C)cc(C(=O)CSc2nnnn2C)c1C +Nc1cnn(CCCc2ccc3c(c2)CCC(=O)N3)c1 +COC(=O)c1[nH]c(C)cc1NC(=O)c1cnn(-c2ccccn2)c1C +Cc1nc2n(n1)CCCC2NC(=O)NCC1OCCc2sccc21 +COc1ccc(OC)c(C(=O)c2cccc(O)c2)c1 +COc1cc(F)ccc1NCC(=O)NC1CCOc2ccccc21 +Cn1cnnc1SCC(=O)N=c1c2ccccc2[nH]c2ccccc12 +CCOc1ccc(C(=O)NC(C)C)c(OCC)c1 +CC(C)c1nnc(SCC(=O)c2ccc(Cl)cc2)o1 +COC(=O)c1ccc2nc(-n3nc(C)cc3N)sc2c1 +Cc1cccc(CC2Oc3ccc(N)cc3N(CCO)C2=O)c1 +CC(NC(=O)Cn1cn[nH]c1=O)c1cccc(Br)c1 +Cc1cc(NC(=O)C2CCC2)n(-c2ccc(C(F)(F)F)cn2)n1 +Cc1oc(-c2ccc(Cl)cc2Cl)cc1C(=O)NCCO +Cc1ccc(Nc2nc(N)nc(CSc3nccn3C)n2)cc1 +CNC(=O)C(C)NC(=O)C1(Sc2ccc(C)cc2)CCCC1 +CC(C)CNC(=O)c1ccc(NC(=O)c2cccs2)cc1 +O=C(OCc1ccccc1F)c1c[nH]c(C(=O)N2CCCC2)c1 +O=C(NCC1(c2ccccc2)CC1)c1cccnc1-n1cncn1 +CCCOc1cc(C)c(S(=O)(=O)Nc2ccccn2)cc1C +CC(=O)c1ccc(OC2CCN(CC(F)(F)F)C2=O)c(C)c1 +COc1ccccc1C(=O)NCC(=O)NCCc1ccccc1F +O=C(CCN1Cc2ccccc2C1=O)N1CCNCC1 +COc1ccc(OC)c(NC(=O)CN2C(=O)COc3ccccc32)c1 +CN(C)S(=O)(=O)N(CCCO)Cc1ccc(Cl)c(Cl)c1 +O=C(CC(c1ccccc1)c1ccco1)N1CC(n2cccn2)C1 +CS(=O)(=O)N(CCO)c1cccc(Cl)c1Cl +CCNC(=O)CS(=O)(=O)c1nncn1-c1ccc(C)cc1C +CC(C)N(Cc1ccccn1)C(=O)Nc1ccc(Cl)cc1 +CCCOc1ncccc1CNC(=O)c1c[nH]c2cccc(F)c12 +Cc1nsc(N2CCCN(Cc3nc4ccccc4n3C)CC2)n1 +CC(C)OCCC(=O)Nc1ccnc(C2CCCC2)n1 +O=C1COc2cc(NC(=O)c3ccnc4ccccc34)ccc2N1 +CCOc1ccccc1NC(=O)Nc1ccc(NC(C)=O)cc1 +CC1(c2ccccc2)CCCN(C(=O)c2cnn3ccccc23)C1 +COC(=O)c1ccc(NC(=O)Cc2cn3ccsc3n2)cc1 +O=C(Nc1ccccc1)Nc1ccc(NCc2ccccn2)cc1 +CC1CC1C(=O)Nc1cccc(C#Cc2ccccn2)c1 +Cc1cc(C)n(CCN2CCN(C(=O)c3csc(C)n3)CC2)n1 +CCOc1ccc(NC(=O)N2CCCC2)cc1F +O=S(=O)(c1ccc(Cl)c(Cl)c1)N1CCOCC1C1CC1 +CN(C)c1ccc(C2CCN(C(=O)c3ccncc3)CC2)nc1 +CCC1CNc2cc(S(=O)(=O)N(C)C)ccc2O1 +CCn1cc(NC(=O)Nc2ccc(NC(C)=O)cc2)c2ccccc21 +O=C(Cc1ccc(F)c(F)c1)NC(Cn1cccn1)c1ccccc1 +CC(C)N(Cc1ccccc1Cl)C(=O)CCn1cccn1 +COc1ccc(CC(=O)Nc2ccc(OC)cc2OC)cc1 +Cc1ccc(C)c(SCC(=O)N2CCNCC2)c1 +Cc1nc(C(C)NC2=NC=NC3=NC=NC32)c(C)s1 +CC1CCN(C(=O)CCCNC(=O)c2ccsc2)C(C)C1 +CC1(C)Oc2ccc(NC(=O)Nc3cn[nH]c3)cc2O1 +O=S(=O)(NCc1cn[nH]c1)c1ccc2ccccc2c1 +O=C(CCc1cc(Cl)cs1)N1CCC(O)C1 +COc1ccc(C)cc1C(=O)CCC(=O)N1CCCCCC1 +O=C(COC(=O)c1ccc2ccccc2n1)Nc1ccc2c(c1)CCC2 +N#Cc1ccccc1NC(=O)C1CN(C(=O)c2cnccn2)C1 +Cc1nc2ccc(C(=O)NC3CCOc4ccccc43)cc2nc1C +Cc1ncsc1CNS(=O)(=O)c1ccc(=O)[nH]c1 +COC(=O)CCN1CCN(C(=O)c2ccco2)CC1 +C=CCn1c(-c2nccn2CCC(N)=O)nc2ccccc21 +CCOC(=O)C1=C(C)C(C(=O)NCC(=O)OC)=NC1C +CC(=O)N1CCC(C(=O)N2CCOCC2C2CC2)C1 +NC(=O)c1cn(CC(=O)N2CC3CC=CCC3C2)c2ccccc12 +CCN(CC)C(=O)c1cn(CCC#N)nc1-c1ccc2ccccc2c1 +COc1ccc(NC(=O)NC(C)c2ccncc2)cc1NC(C)=O +Cc1c(O)ccc2c1C(c1ccncc1Cl)NCC2 +COc1c(C2CCCN2C(=O)C2CCOC2)c(C)nn1C +COc1cccc(C(=O)N(C)Cc2cnn(C)c2)c1O +COCCN1CCN(C(=O)NC(c2nccs2)C2CC2)CC1=O +CCN(CC)c1ccc(C(=O)Nc2cccc(NC(C)=O)c2)cn1 +CC(C)NC(=O)C12CC3CC(C1)CC(C(=O)NC(C)C)(C3)C2 +CCCC(C)NC(=O)C(C)Sc1nc(C)cc(C)c1C#N +CN(C)C(=O)N1CCN(C(=O)NCc2cccnc2)CC1 +CC(=O)N1CCC(C(=O)NCc2ccc(Cn3cccn3)cc2)CC1 +Cc1ccc(N2CC(c3nc(-c4ccncc4)no3)CC2=O)cc1 +Cn1nccc1NC(=O)Cn1ccc(-c2ccncc2)n1 +CC1CCCCN1C(=O)c1cccc(-n2cnnn2)c1 +O=C(NCCc1ccc2c(c1)OCO2)C1COc2ccccc2O1 +Cc1cc(NC(=O)N2CCN(Cc3ccc4c(c3)OCO4)CC2)no1 +CC1CCC(NC(=O)COc2ccc3ccc(=O)oc3c2)CC1 +Cn1nc(CC(=O)N2CCOC3CCCC32)c2ccccc2c1=O +CCC(=O)N1CCc2c(C(=O)NCc3cccc(Cl)c3)cccc21 +C#CCNS(=O)(=O)c1cccc(C(=O)NCCNC(C)=O)c1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)N1CCCCC1C)O2 +CC(C)(C)c1csc(NC(=O)c2cn3ccccc3n2)n1 +COc1cc(CCc2nc(-c3ccnc(OC)c3)no2)cc(OC)c1 +CC(NCc1ccccc1F)C(=O)Nc1ccccc1F +O=C(NC1CCN(C(=O)Nc2ccccc2Cl)CC1)c1ccco1 +CS(=O)(=O)c1ccc(NCCC2CCCCC2)cc1 +Cc1ccccc1-c1noc(CNS(C)(=O)=O)n1 +O=C(CC1CCc2ccccc21)NCCc1ccncc1 +O=C(NCc1nncn1C1CC1)Nc1cccc(N2CCCC2=O)c1 +O=C(C1CCC1)N1CC2CCC(C1)N(S(=O)(=O)c1cccnc1)C2 +NC(=O)Cc1ccc(NC(=O)c2ccc(OCC(F)F)nc2)cc1 +CS(=O)(=O)c1ccc2c(c1)NC(=O)C(c1ccccc1)O2 +COc1ccccc1S(=O)(=O)NCC(=O)NC(C)(C)C +Cn1ncc(-c2cccc(Cl)c2)c(CC#N)c1=O +O=C(Cc1ccccc1)Nc1ccc(NC(=O)c2ccco2)cc1O +CC(C)n1ccc(=O)nc1SCC(=O)NCc1cccnc1 +Cc1nnc(SC(C(=O)N(C)C)c2ccccc2)s1 +CC(=O)NCC(=O)Nc1ccn(-c2cccc(C(F)(F)F)c2)n1 +O=C(Cc1csc(-c2ccccc2)n1)NCCCO +Cc1nc(CN2CCN(C(=O)CNC(=O)C(C)(C)C)CC2)cs1 +CCCN(CCC)C(=O)C1CCN(Cc2nc3ccccc3[nH]2)CC1 +CC(C)OCc1cccc(NC(=O)NC(CO)c2ccccc2)c1 +Cc1nnc(-c2cc(C)n(CC(=O)Nc3cccc(F)c3)c2C)o1 +CC(=O)N1CCc2cc(NC(=O)c3ccccc3-n3cccn3)ccc21 +CCOCC(=O)Nc1ccc2c3c(cccc13)CC2 +CC1CCN(C(=O)CSc2ncn[nH]2)c2ccccc2S1 +Cc1csc(CNC(=O)NCc2ccc3c(c2)OCCO3)n1 +COc1ccccc1NC(=O)CSc1nc(C)ccc1C#N +CCc1csc(C2CCCN(C(=O)c3c(C)nn(C)c3OC)C2)n1 +CC1CCCN(c2ncnc3c2cnn3-c2ccccc2)C1 +NC(=O)CCN1CCN(C(=O)c2ccc(F)cc2)CC1 +Nc1nc(N2CCN(C(=O)CCC3CCCC3)CC2)nc2[nH]ncc12 +CCC(C)(CO)NC(=O)Nc1cc(OC)ccc1F +CC(C)COC(=O)N1CCCN(c2ccc3nccn3n2)CC1 +O=C(Oc1ccc(-n2cnnn2)cc1)c1ccccc1 +CSc1ccc(CNC(=O)c2cccnc2SC)cc1 +O=C1NCCN1C1CCN(c2nnnn2-c2ccccc2)CC1 +O=C(CCC1Cc2ccccc2NC1=O)OCc1nc2ccccc2[nH]1 +Cc1nn(-c2ccc(C(=O)NC(C)C)cc2)c(C)c1Cl +Cc1occc1C(=O)N1CCN(Cc2cccc(F)c2F)CC1 +CCC(C)OC(=O)CN1C(=O)COc2ccc(N)nc21 +CC(C)Cc1ncc2c(n1)CN(c1ccc(C#N)cn1)C2 +CC1CCCCN1C(=O)CN1CCN(C(=O)c2cnns2)CC1 +Cc1cc(C)n(-c2ccc(CNC(=O)C3CC4C=CC3C4)cn2)n1 +COc1ccc(C(=O)N2CC(c3ccc(F)cc3)CC2C)cc1OC +Nc1ccc(-c2cc(C(=O)N3CCCC3)ccn2)cn1 +Cc1ccnc(N2CCC(CNC(=O)OC(C)(C)C)C2)n1 +Cc1n[nH]c(C)c1SCC(=O)Nc1cccc(Br)c1 +CCCCNC(=O)c1c(C)[nH]c(C(=O)OCC)c1C +CCn1c(SC(C)C(=O)OC)nnc1-c1ccncc1 +Cc1cc(C)c(NC(=O)CCc2c(C)noc2C)c(C)n1 +Cc1cc(F)ccc1C(N)C(=O)NCc1ccco1 +CCCOc1nc(C(C)(C)C)nc(NC(C)C)c1N +CCOC(=O)CCNC(=O)c1sccc1CC +O=c1nc(SCc2ccccc2)c2c(n1CC1CCCO1)CCC2 +O=C(NCCc1cn2ccsc2n1)C1CCCCO1 +CC(O)CCn1cnc2cc(Cl)ccc2c1=O +Nc1c(NCCCO)c(=O)[nH]c(=O)n1Cc1ccccc1 +Nc1ccc2c(c1)C(CSc1ncccn1)NCC2 +CC(Cc1noc(-c2c[nH]c(C#N)c2)n1)N(C)C(=O)OC(C)(C)C +Cc1nonc1C1Cc2cccc(Br)c2C1 +COC(=O)CNC(=O)C(N)c1ccc(OC)cc1 +CCN(Cc1ccco1)C(=O)c1[nH]c2c(c1C)C(=O)CC(C)(C)C2 +CCc1noc(C)c1C(=O)NC(C)c1ccccc1 +CNC(=O)c1cccc(CCNC(=O)NCc2cc(C)oc2C)c1 +CC(OC(=O)c1nc(-c2ccccc2)n2c1CCCCC2)C(N)=O +COc1cccc2cc(-c3ccnc(-c4ccncc4)n3)oc12 +O=c1c(=Cc2cccc(F)c2)sc2nc(-c3ccncc3)nn12 +CCOCCNC(=O)CCc1c(C)nc2nc(N)nn2c1C +CCCC(=O)N1CCCC(C(=O)NCCCc2cn[nH]c2C)C1 +Nc1ccc(=O)n(CCOc2cc(Cl)ccc2Cl)c1 +OCCC1CN(c2ncccc2Cl)CCN1Cc1ccccc1 +Cc1cccc(C)c1NC(=O)CNC(=O)Cc1ccccc1F +CCC(C)(NC(=O)C1CCCN(C(=O)C2CC2)C1)c1nc(C)cs1 +CNC(=O)c1cc2cc(Br)ccc2s1 +Cc1cc(C(=O)NC(C)Cc2ccsc2)c(=O)[nH]c1C +Cn1c(C2CC2)nc2cc(NC(=O)CC(C)(C)C)ccc21 +Cn1c(SCC(=O)NCCc2ccc(F)cc2)nc2ccccc21 +COc1ccc(C(=O)NCC(C)c2ccccc2)cc1OC +COc1ccc2cccc(CC(=O)NCC(O)c3cccs3)c2c1 +O=C(COc1ncnc2sccc12)Nc1ccc(Cl)cc1 +CC1CC1C(=O)N1CCN(CCC(F)(F)F)CC1 +CCC(=O)Nc1cccc(C(=O)N2CCC(O)(C(F)(F)F)C2)c1 +CCC(NC(=O)Nc1ccncc1)c1ccc(Br)cc1 +CCn1c(C(O)c2cc(OC)ccc2OC)nc2ccccc21 +COCn1c(CCOc2ccccc2)nc2c(N)cccc21 +COCc1nc(C)c(C(=O)N(C)c2ccc(Cl)cn2)s1 +Cc1nc(CC(=O)NC2CCCC(C(F)(F)F)C2)cs1 +O=C(NCC1CCOc2ccccc21)c1cnc(C2CCCO2)s1 +CCN(CC1COc2ccccc2O1)C(=O)c1cc(C(C)(C)C)n[nH]1 +O=C(CCC(=O)c1cccs1)NCc1ccncc1 +CCCNC(=O)CC1CCN(C(=O)c2[nH]c(C)cc2C)CC1 +COCCc1nnc2sc(-c3cccc(N)c3C)nn12 +Cc1ccc(NC(=O)CCNC(=O)C(C)(C)C)cc1C(=O)NC(C)C +COc1ccccc1CSc1nnc(-c2cccnc2)n1C +Cc1cccc(OC(=O)CSc2ccncc2)c1C +CCCOCCNC(=O)c1cnc(-c2ccncc2)nc1 +COc1ccc(C(C)=O)cc1CC(=O)N1CCOCC1C1CC1 +C#Cc1cccc(NC(=O)CCCNC(=O)c2ccco2)c1 +COc1cccc(N2CCN(C(=O)CC(C)(C)C)C(C)C2=O)c1 +CC(C)COC(=O)CN1C(=O)C(C)Oc2cccc(N)c21 +Cc1ccc(OCCNC(=O)C(C)Cn2cccn2)cc1 +Cc1ncc(CN2CCCC3(C2)OCCO3)n1-c1ccccc1 +O=C(OCCNc1ncccn1)c1cccc2ncccc12 +Cc1noc(C)c1CS(=O)(=O)c1ccc(C(F)(F)F)cn1 +COc1ccc(CNC(=O)c2cccc(OCC(N)=O)c2)cc1 +CC(CCOc1ccccc1)C(=O)N1CCCC1C(N)=O +CC(CO)NC(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +CCOC(=O)Cc1csc2nc(C(C)(C)C)c(N)n12 +O=C(CCc1nc(-c2ccccc2)no1)NCc1cnn2cccnc12 +Cc1nnc(-n2nnc(C(=O)OC3CCCCC3)c2N)s1 +Cc1cccc(NC(=O)C2CCCN(c3cnccn3)C2)c1 +Cc1ccc(C(=O)CCC(=O)Nc2c(C)nn(C)c2C)cc1 +CN(C)c1ccccc1C#CCNC(=O)c1cc(-c2ccccc2)n[nH]1 +NC(=O)CNC(=O)COc1ccc2oc3c(c2c1)CCCC3 +CC(C)n1cc(NC(=O)C2CCCCN2C(=O)OC(C)(C)C)cn1 +Cc1nc2ncnn2c(C)c1CCC(=O)N(C)Cc1cccc(C#N)c1 +COC(C)(C)c1noc(CNC(=O)c2ccc(Cl)c(Cl)c2)n1 +COc1cc(N)ccc1NC(=O)CCOCCO +COc1ccc(C=Cc2nn3c(-c4ccncc4)nnc3s2)cc1 +CC(NC(=O)Cn1cnnn1)c1ccc(Cl)c(Cl)c1 +CNC(=O)c1ccc(NC(=O)CNc2ccccc2OC(C)C)cc1 +COC(=O)CN(C)C(=O)c1ccc(Br)cc1C +O=C(C1CC1c1ccccc1)N1CCC(CN2CCOCC2)CC1 +CC(=O)NC(CC(=O)OCc1ccc(C#N)cc1)c1ccc(C)cc1 +Cc1cc(NC(=O)CSc2nc3ccccc3o2)no1 +Cc1cc(C)n(CC2CCCCN2C(=O)CNS(C)(=O)=O)n1 +CCOc1cccc2c1OCCC2(N)C(=O)OC +Cn1nc2c(c1NC(=O)c1ccc(NC3CC3)nc1)CCC2 +CC(C)c1noc2nc(C3CC3)cc(C(=O)NCCO)c12 +CSc1ccc(CN(CCO)C(=O)C2C=CC=N2)cc1 +CCn1c(SCC2(CO)COC2)nnc1-c1cccs1 +CC(=O)c1cc(N)cc2nc(-c3ccccc3F)oc12 +CCOC(=O)C1=C(CN(C)C(C)c2cccs2)NC(=O)NC1 +O=C(NCc1cccc(O)c1)c1cc(F)c(Cl)cc1Cl +O=C(c1ccc(Cl)cc1)N1CCC(n2nnc3ccccc32)CC1 +Nc1ncc(C(F)(F)F)cc1Nc1cccc(O)c1 +CSc1nc(C)c(CCc2nc(-c3ccsc3)no2)c(=O)[nH]1 +CC(=O)N1CCN(C(=O)c2ccc(N)c(C)c2)CC1 +CSc1cccc(NC(=O)c2ccc(NC(N)=O)cc2)c1 +COc1ccc(F)c(NC(=O)c2ccc(C#N)cn2)c1 +C=CCn1c(C)nnc1SC(C)C(=O)N1CCC(C)CC1 +COc1ccccc1OC1CN(C(=O)c2ccc(Cl)cc2F)C1 +CN(C(=O)C1Cc2ccccc2CN1)C1CCOCC1 +COc1ncccc1CN(C)C(=O)c1ccc(C)nc1 +C#CCOc1ccc(C(=O)NCc2ccccn2)cc1 +Cc1ccc(C(=O)N(C)C(C)c2nc3ccccc3s2)cc1 +Cc1nn(C)c(C)c1S(=O)(=O)NC(C)(C)C(=O)N(C)C +O=C(CSc1nnnn1C1CCCC1)Nc1nnc2ccccn12 +CCn1ncc(Br)c1C(=O)NCc1ccc(OC)cc1 +COc1cc2[nH]c(C(C)(C)C)cc(=O)c2cc1OC +CCC(C)NC(=O)NCCc1ccc2c(c1)OCCO2 +O=C(CSc1nnc(C2CC2)o1)Nc1ccc2c(c1)OCCO2 +O=C(CCn1ccc2cc(Cl)ccc21)NCC(O)c1ccncc1 +CS(=O)(=O)c1ccc(NC(=O)c2cc(F)cc(F)c2)cc1 +Cc1ccc(S(=O)(=O)N2CCCC2CCCO)s1 +CN(C)C=C(NC(=O)Nc1ccc(F)c(F)c1F)C(F)(F)F +CCOC(=O)c1ccc(N2CCN(C(C)CC#N)CC2)nc1 +CCN(CC1CCCO1)C(=O)NCc1ccccc1N1CCCC1 +CC1COCC(C)N1C(=O)c1cnn2c(-c3ccccc3)ccnc12 +N#CCCn1c(-c2ccccc2F)nc2cccc(F)c21 +COc1c(C)cc(Cl)cc1CC(=O)NCCO +O=C(NCc1ccc(Cl)cc1Cl)Nc1ccncc1 +Cc1cc(C(=O)NCCC(O)c2cccc3ccccc23)c(C)o1 +C#CCNC(=O)NC(C)c1ccccc1Br +Cc1cccc(-n2c(C)cc(C)c3c(=O)[nH]c(=O)nc2-3)c1 +CNC(=O)C1CCN(S(=O)(=O)c2cc(Cl)ccc2C)CC1 +COC(=O)C1CCC(NC(=O)Nc2cnccc2C)CC1 +CC1CN(S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)CC(C)O1 +Cc1cc(C)n(C(C)C(=O)NC2CCN(c3ccccc3)C2)n1 +Cc1cc(C)c(NC(=O)C2(C)CC2(Cl)Cl)c(C)n1 +NC(=O)c1ccsc1NC(=O)COC(=O)Cc1ccccc1 +CCN(Cc1ccccc1Cl)C(=O)c1cc(NC(C)=O)ccc1F +CC(NC(=O)NCCc1cc2ccccc2o1)c1nncn1C +NC(=O)C(CNC(=O)c1cc(C2CC2)[nH]n1)Cc1ccc(F)cc1 +CC(=O)Nc1nc2c(C)cc(NC(=O)C(C)C)cc2s1 +Cc1cc2cc(NC(=O)CCc3c(C)n[nH]c3C)ccc2o1 +O=C(NCC1(Sc2ccccc2)CC1)c1cn2cccnc2n1 +Cc1nc(NCCCn2ccnc2)cc(-c2ccccn2)n1 +Cc1nc(N)nc(-c2cc3c(cc2C)OCCO3)n1 +COc1ccc(-c2n[nH]cc2CN(C)CCc2cnn(C)c2)c(F)c1 +Cc1ccc(C(=O)NCCC(=O)Nn2c(C)cc(C)cc2=O)cc1 +CCOC(=O)c1c(Cl)c2ccc(Cl)cc2[nH]c1=O +Cc1ccc(OCc2nc(C)c(CCO)c(=O)[nH]2)cc1 +COCCN(Cc1ccco1)C(=O)c1cc(F)c(F)cc1Cl +CCC(C)N1CNc2c(c(=O)[nH]c(=O)n2-c2ccccc2C)C1 +CN(Cc1nc2ccccc2[nH]1)S(=O)(=O)c1ccc2c(c1)CCO2 +CCn1cc2c(n1)CN(Cc1nccs1)CC2COCC1CC1 +CS(=O)(=O)N1CCN(C(=O)c2cccc(C(F)(F)F)c2)CC1 +CCN(CC)C(=O)c1cccc(S(=O)(=O)Nc2cccc(C)c2)c1 +CCCN(C)C(=O)C1(NC(=O)NCC)CCCC1 +CN(CC1CCC1)C(=O)C1CCCN(C(=O)COc2ccccc2)C1 +Cc1cc(NC(=O)c2cnn(-c3ccc(F)cc3)c2C)n(C)n1 +CC(C(=O)NC1CC1)N1CCN(C(=O)c2cnns2)CC1 +CCN(CC)C(=O)CN1CCN(C(=O)Nc2cnccc2C)CC1 +Cc1n[nH]c(C)c1CCC(=O)Nc1nc(CN2CCOCC2)cs1 +CCOC(=O)N1CCC(NC(=O)CN2c3ccccc3CC2C)CC1 +CC(C)NC(=O)c1cc(=O)c(OCc2ccc(Cl)cc2)co1 +CC1(C)Oc2ccc(O)cc2N(Cc2ccccc2)C1=O +CSc1ccccc1C(=O)N(C)Cc1nc(-c2cccs2)no1 +NC(=O)CC1CCN(C(=O)NCC2Cc3ccccc3O2)CC1 +CC1=CC(C)=NC(=O)C1CNC(=O)Cn1c(=O)n(C)c2ccccc21 +Cc1nc2cc(C(=O)CN3CCOCC3)ccc2[nH]1 +COc1ccc(C(=O)NCCOc2ccc(C)cc2)cc1F +CCc1csc(-c2cn(CC(=O)NCc3cccs3)cn2)n1 +CC(C)COc1cc(NCC2CCCO2)nc(C2CC2)n1 +CCOC(=O)C1CCCN1C(=O)c1cccc(Cl)c1 +CC1=C(C(=O)N2CCOCC2)C(c2ccccc2F)NC(=O)N1 +O=C(NCC1CCCO1)c1cn(Cc2ccccc2)c2ccccc12 +O=C(NCCNC(=O)N1CCC(Oc2ccccc2)CC1)C1CC1 +COCCN(Cc1cnn(C)c1)C(=O)C1COc2ccccc2C1 +CCNC(=O)Cn1c(CNC(C)=O)nc2ccccc21 +COc1ccc(CCNC(=O)c2cccc(NC(C)=O)c2)cc1OC +CC(C)(C)c1cnc(C(=O)NC2CCCCNC2=O)o1 +Cc1ccccc1-n1nnc(C(=O)NCc2cccnc2)c1C +CC(=O)N1CCN(Cc2cc(-c3ccc(Cl)cc3)no2)CC1 +CNC(=O)C(C)NCc1c(OC)nc2sccn12 +CCC(C)C(NC(=O)C1CCC(C)CC1)C(=O)NCc1ccco1 +CCCS(=O)(=O)NCCn1c(=O)[nH]c2cncnc21 +COc1cccc(CNC(=O)C2COC(=O)N2CC(C)C)c1 +CC(=O)N(C)C1CCN(C(=O)c2nccc3ccccc23)CC1 +COCC(=O)Nc1cccc(NC(=O)N2CCC(=O)NCC2C)c1C +Cn1nnc(-c2ccc(-n3ccnc3-c3ccncc3)cc2)n1 +O=C(CCc1nc2ccccc2s1)NCCCN1CCOCC1 +CC(=O)N1CCN(C(=O)C2CCC2)CC(COc2ccccc2)C1 +NC(=O)CN(C(=O)c1cccc(O)c1)C1CCCC1 +CC(CO)C(C)NC(=O)NCc1ccccc1OC(F)(F)F +COc1ccnc(NC(=O)c2cc(C(C)C)n(-c3ccccc3)n2)c1 +CC(c1ccncc1)N(C)C(=O)Nc1ccccc1Cl +COc1ccccc1S(=O)(=O)NCc1cc2ccccc2o1 +CC1CCN(C(=O)c2c[nH]c3cccc(F)c23)CC1 +CN(CCCc1n[nH]c(N)c1C#N)c1ncccc1C#N +CCOC(=O)CN1CCN(C(=O)Cc2ccccc2C)CC1 +COc1cc(OC)cc(-n2ccc3c(nnc4ncnn43)c2=O)c1 +CCC(C)NC(=O)c1ccc(NC(=O)c2cc(C)n[nH]2)cc1 +NC(=O)CCn1cc(CO)c2cc(Cl)ccc21 +CC(C)(NCC(=O)NC1(C#N)CCCC1)c1ccc2c(c1)OCO2 +COc1ccc(C(=O)C(C)OC(=O)c2ccc(OC)nc2)cc1 +COc1cc(C)c(CN2CCC3(C2)OCCO3)cc1OC +Cc1cc(C)n2ncc(C(=O)NCC3(C(N)=O)CCOCC3)c2n1 +CC(C)c1ccccc1NC(=O)C1CN(C(=O)c2cccs2)C1 +CCS(=O)(=O)NCC(=O)Nc1c(C)cc(C)cc1C +c1coc(-c2nc(CN3CCc4ccccc4C3)cs2)c1 +Cc1csc(NC(=O)c2csc3c2CCC(C)C3)n1 +CCNc1ncc(C(=O)NCCN2CCNC2=O)cn1 +CC(=O)Nc1ccc(C(=O)NC2CCCC(C(F)(F)F)C2)cc1 +CC(C)(C)NS(=O)(=O)c1ccccc1CNC(=O)Cc1ccc[nH]1 +Cc1cccc(NC(=O)NC(CO)c2ccccc2)n1 +Cn1cnnc1S(=O)(=O)CC(=O)NCCc1ccc(Cl)cc1 +CCC(C)NS(=O)(=O)c1ccc(C(=O)Nc2ccccn2)cc1 +CN(C(=O)COC(=O)C1C2CC3CC(C2)CC1C3)C1CC1 +COc1cccc(OCC(=O)Nc2nnc(-c3cccc(F)c3)o2)c1 +COc1ccc(-c2cnc(Cn3nnc4ccccc4c3=O)o2)cc1 +CC1=C(C(=O)Nc2ccccc2)C(c2cccc(F)c2)n2ncnc2N1 +CC(C)=CC(=O)Oc1ccc(N(C)S(C)(=O)=O)cc1 +c1cnc2ccc(OCc3nc4c(s3)CCCN4)cc2c1 +O=C(CCN1CCN(C(=O)C2CC2)CC1)NCc1ccccc1Cl +CCc1cc(NC(=O)c2ccc(C(N)=O)s2)c2ccccc2n1 +CCN(C)c1ccc(C(=O)NCc2noc(C(C)C)n2)cn1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)N(CC(C)C)CC(C)C +N#CCCn1cccc(OCCN2CCOCC2)c1=O +Cc1ccc(-c2ncco2)cc1NC(=O)c1cnns1 +Cc1nn(CC(=O)Nc2ccc(F)c(F)c2)c(C)c1Cl +Cc1ccccc1NC(=O)c1n[nH]c2c1COc1ccccc1-2 +FC(F)(F)c1ccnc(-n2nnc3ccccc32)n1 +CCNC(=O)c1cccc(NC(=O)c2ccc(OC)cc2)c1 +N#Cc1cccc(S(=O)(=O)NC(c2ccccc2)c2ccncc2)c1 +COc1cccc(OC)c1C(=O)Nc1ccc(-n2ccc(C)n2)cc1 +COc1cc(OC)cc(C(=O)OCC(=O)c2ccccc2)c1 +CC(c1ccncc1)N(C)C(=O)c1cccc(-c2cn[nH]c2)c1 +COC(=O)c1ccc(F)c(CNC(=O)Cc2c(C)noc2C)c1 +CCN(CCO)C(=O)CCc1ccc(OC)c(F)c1 +Fc1ccc(CSc2nnc(C3CC3)n2C2CC2)cc1 +CCCC(=O)Nc1ccc(C(=O)NCC(=O)OC)cc1 +CSc1ccc(Cl)c(C(=O)NC(C)c2cnn(C)c2C)c1 +CC(Oc1ccccc1N)C(=O)OCc1ccccc1 +CC(C)N1C(=O)c2ccc(C(=O)NCc3ccco3)cc2S1(=O)=O +N#CC1(c2ccccc2)CCN(C(=O)c2cccc3nccnc23)CC1 +CNS(=O)(=O)c1cccc(C(=O)NCC2Cc3ccccc3O2)c1 +O=C(C1CCCCC1)N1CCCC(c2nnc(-c3ccccc3)o2)C1 +CCNc1nnc(-c2cccn(CC3CCCO3)c2=O)s1 +Cc1ccc2nc(SCC(N)=O)n(C)c(=O)c2c1 +CC(c1ccc(O)cc1)N(C)C(=O)Cn1cccn1 +O=c1c(O)cc(S(=O)(=O)c2ccccc2)c2n1CCC2 +Cc1ccc(-c2nc(CCNC(=O)Cn3cc(C)cn3)cs2)cc1 +CCCCc1cc(C(=O)OC)n(-c2ccccn2)n1 +CSc1nc(C(=O)NC(C)(C)C)c2ccccn12 +Nc1nccc(C2CCCN2CCc2ccccc2)n1 +Cc1nnc(C2CC3OCCC3N(Cc3ccoc3)C2)o1 +CNC(=O)NCC(=O)NCC1(c2ccccc2)CCC1 +COCc1cccc(C(=O)NCc2ccc(Cl)cc2)c1 +C#CCN(Cc1ccco1)C(=O)c1cc(C2CC2)[nH]n1 +Cc1ccc(CCNC(=O)NCC(C)(O)c2ccccc2Cl)cn1 +CN(CC1CC1)C(=O)CNc1ccc(Br)cc1 +N#Cc1ccc(C(=O)N2CCN(c3ncnc4ccccc34)CC2)cn1 +Cn1cnc2cc(-c3nc(C4CCOC4)no3)ccc21 +COc1cccc(C(=O)c2cc(N)ccc2OC(F)F)c1 +CC(C)(C)OC(=O)N1CCn2c(CO)nnc2C1 +CCN(CC1CC1)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +O=C(Cc1ccccc1)N1CCN(c2ccc(-n3cncn3)nn2)CC1 +O=C(Nc1nc2ccc(Cl)cn2n1)NC(CO)c1ccccc1 +CC(NC(=O)CNS(C)(=O)=O)c1cccc(C(F)(F)F)c1 +CCOc1ccc(C(=O)n2nc(C)cc2C)cc1OC +Cc1ncsc1C(=O)N1CCCC1c1nnc2ccccn12 +CC1Oc2ccc(N)cc2N=C1Nc1cccc(F)c1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1cc(F)cc(Cl)c1O +CCCC1CN(C(=O)Nc2cccc(-c3noc(C)n3)c2)CCO1 +COc1ccsc1C(=O)N1CCN(CCO)CC1 +Cc1cc(N2CCCc3ccccc32)n2ncnc2n1 +O=C(NC1c2ccccc2CC1O)c1cnn2c1CCCC2 +COc1ccc(Cl)c2sc(NCC3CCCO3)nc12 +Cc1cc(C)c2c(=O)n(CC(=O)Nc3ccc(C)c(F)c3)sc2n1 +Cc1ccc(C(C)(O)CNCc2ccccn2)cc1C +CCCc1cc(C(=O)N(C)CC2CC(=O)N(C3CCCC3)C2)no1 +Cn1cc(Cl)cc1C(=O)N1CCC(C)(O)C(C)(C)C1 +CCOc1ccc(C(=O)Nc2ccccc2NC(C)=O)cc1OCC +Cc1ccn2cc(C(=O)N3CCN(Cc4ccccc4)CC3)nc2c1 +Cc1ccc(CO)cc1NC(=O)c1ccc(Br)cn1 +CN1CCC(C(=O)NCCc2cnn(C)c2)CC1=O +O=C(CC1C=CCC1)N1CCN(c2ccccc2O)CC1 +CCOc1ccc(F)c(C(=O)Nc2cccc(C)n2)c1F +O=C1C(=O)N(Cc2ccccc2)c2c(Br)cccc21 +CCOC(=O)c1cccc(NS(=O)(=O)c2ccc(F)cc2)c1C +CCCN1C(=O)C(=O)c2cc(Br)cc(C)c21 +Cc1cc(C)c2[nH]c(CN(C)CC3(CO)CCOCC3)cc(=O)c2c1 +COc1ccc(Cl)cc1NC(=O)CCNS(C)(=O)=O +COc1cccc(-c2nc(C(=O)NCCN3CCOCC3)cs2)c1 +Cc1cc(C)n2c(SCC(=O)Nc3cc(C)on3)nnc2n1 +Cn1ncc2cccc(-c3nc4ccc(N)cc4[nH]3)c21 +Cc1ccc(OCCCCNC(=O)c2ccoc2C)cc1 +CCC(C)NC(=O)C(C)NC(=O)CN(C)S(C)(=O)=O +CCOc1ccc(NS(=O)(=O)c2cccs2)cc1CO +CC(CCc1ccc(Br)cc1)NC(=O)CNC(N)=O +Nc1c(-c2cccnc2)nnn1-c1cc(Cl)ccc1O +O=S(=O)(c1ccc(F)cc1)N1CCC(Oc2cccnc2)CC1 +O=C(NC1CCC(O)CC1)c1cccc(COc2cccc(F)c2)c1 +COc1ccc(OC)c(NC(=O)CNC(=O)c2ccco2)c1 +CCN(CCO)C(=O)C(C)Oc1cccc(F)c1 +Cc1ccc2ncc(C(=O)N(C)c3ccc(F)cc3)c(=O)n2c1 +O=C(Nc1ccc(-n2ccnn2)cc1)c1ccnc(OC2CCC2)c1 +CCOC(=O)c1[nH]c(C)c(C(=O)NCC(=O)NC(C)(C)C)c1C +O=C(NCCc1ccccn1)C1CCCN(C(=O)c2cccs2)C1 +CCOc1ccc(C(=O)Cc2ncc(C)s2)cc1N +Cc1cc(C(=O)N2CCC(n3cc(-c4ccsc4)nn3)CC2)no1 +Cc1noc(C)c1C(C)NC(=O)N1c2ccccc2CC1C +COc1ccc(S(=O)(=O)NCCc2cccc3cccnc23)cc1 +Cc1cc(C)c(C)c(OC(=O)Cn2nnc3ccccc3c2=O)c1 +Cc1noc(C)c1S(=O)(=O)NC(C)c1ccc2ccccc2c1 +COC(=O)CCCCNC(=O)Nc1ccc(C)cc1C +COC(=O)c1ccc(C(=O)Nc2c(C)cccc2C(C)C)cn1 +O=c1n(Cc2cc(Cl)c3c(c2)OCO3)nnn1-c1ccccc1 +COc1ccc(C(=O)N(C)Cc2ccsc2)c(O)c1 +COC(=O)N1CCC2(CC1)NC(CCC(C)C)=NC2=O +COC(=O)CNC(=O)C1CC(=O)N(C(C)c2ccccc2)C1 +Cc1c(C(=O)Nc2ccc3c(c2)COC3)cnn1C1CCOCC1 +CCS(=O)(=O)N1CCC(C(=O)Nc2cc(C)on2)CC1 +CNC(=O)c1ccc(Cl)c(NC(=O)COc2cccc(OC)c2)c1 +COc1ccc(OC)c2c1CC(C(=O)N1CCCC1)CC2=O +COC(=O)NCCC(=O)NCC(C)(O)c1ccc(F)cc1 +CCn1nc(C)cc1C(=O)Nc1cccc(Cn2nc(C)cc2C)c1 +Cc1nn(-c2ccccc2)c2[nH]c(-c3cccnc3)cc(=O)c12 +Cc1cccc(OCCC(=O)NCC2CN(C)CCO2)c1C +N#Cc1cccc(C(=O)NCCNc2nnnn2-c2ccccc2)c1 +CCCC(=O)N(CC1CCCO1)c1nc2ccccc2s1 +CC(C)(C)C(=O)Cn1nnc(-c2ccc(C(N)=O)cc2)n1 +Cc1cc(OCC(=O)c2ccc(F)cc2)nc(-c2ccncc2)n1 +CCS(=O)(=O)NCC(=O)Nc1ccc(C)cc1Cl +COc1cccc(Cn2c(=O)c(C)nc3ccccc32)c1 +CC(=O)Nc1nc(C(=O)N(C)c2ccc3ccccc3c2)cs1 +O=C(OCCn1cncn1)c1ncn(-c2ccccc2)n1 +CC(c1ccc(O)cc1)N(C)C(=O)Cc1cccs1 +COc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1N +O=C(NCC(=O)N1CCN(c2ncccn2)CC1)c1ccc(=O)[nH]c1 +O=C(Nc1nccs1)c1ccc(-n2cnnn2)cc1 +CCn1c(SCc2noc(-c3ccoc3)n2)nc2ccccc21 +COc1ccc(SCCC(=O)N(C)Cc2ccoc2C)cc1 +CCOc1ccc(C#N)cc1NC(=O)c1occc1C +Nc1cc(F)ccc1C(=O)OCC(=O)Nc1ccc(F)c(F)c1 +COc1cccc(SC(C)C(=O)NCc2cccs2)c1 +Cc1ccc(C(=O)Nc2ccc(S(=O)(=O)NC(C)C)cc2)o1 +CC(C)(C)NC(=O)Nc1ccc(Br)cc1 +O=C(c1ccc(Cn2cncn2)cc1)N1CCCCC1 +C=CCn1c(SCc2ccc(F)cc2)nc2c1c(=O)[nH]c(=O)n2C +COc1ccccc1CNC(=O)c1cnc2sc(C)cn2c1=O +COc1ccc(C(=O)OCC(=O)NC(C)c2ccccc2)cc1F +COc1ccc(CCc2n[nH]c(C)c2NC(=O)C2CC2)cc1 +CCc1nn(CC(=O)OC)c(=O)c2cc3sc(C)cc3n12 +Cc1sc2ncnc(N3CCOCC3)c2c1-c1ccc(F)cc1 +CC(=O)c1ccccc1NC(=O)c1cncn1-c1ccccc1 +NS(=O)(=O)c1ccc(NC(=O)c2c(F)cccc2Cl)cc1 +COCc1cccc(CNC2Cc3ccccc3C2)c1 +CC(=O)Nc1cccc(C(=O)N2CCN(Cc3cc(C)on3)CC2)c1 +CCOC(=O)C(NC)c1nc2cc(C(N)=O)ccc2n1C +CN(c1ccccc1F)c1ncc(N)cc1Br +O=C(NCc1cc2ccccc2o1)NCC(O)c1ccccc1Cl +Cc1ccc(NC(=O)C23CCC(C)(C(=O)C2)C3(C)C)cc1C +COc1ccc(C2CCCN2C(=O)c2c[nH]c3cccc(F)c23)cc1 +Cc1[nH]nc2c1NC(c1ccc(C#N)cc1)NC2=O +CCC(=O)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1 +COC(=O)C1CCCN1Cc1ccc(C#N)cc1F +Cc1c(N)c(-c2ccc3oc(=O)n(C)c3c2)nn1C +CCN(C(=O)CSc1nnc(C)s1)C1CCCCC1 +CCOc1cccc(C(C)NS(=O)(=O)c2c(C)nn(C)c2C)c1 +CCS(=O)(=O)NCCS(=O)(=O)N1CC(C)CCC1C +Cc1nn(C)c(C)c1NC(=O)CNc1ccccc1N1CCCC1=O +CC(C)OCCCNC(=O)C(N)c1cccc(F)c1 +O=C(CC1CCc2ccccc21)NCc1nncn1C1CCCCC1 +CN1CCN(C(=O)CNC(=O)Cn2ccc3ccccc3c2=O)CC1 +COC(C)C(=O)Nc1cccc(-c2nc3ccccc3[nH]2)c1 +COC(=O)C(NC(=O)Cc1ccc(-n2cccn2)cc1)c1ccccc1 +CC(=O)Nc1ccc(Cl)cc1NC(=O)c1nccc2ccccc12 +Cc1ccccc1-c1nsc(C(=O)NCC(C)C)c1N +Cc1cc(C(=O)CN2CCC(C(=O)N3CCOCC3)CC2)c(C)[nH]1 +CCN(CC1CC1)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +CC(NS(=O)(=O)c1cccc(F)c1)c1nnc2n1CCCCC2 +CC(C)c1cc(C(=O)NCCc2nc(-c3cccnc3)no2)on1 +NS(=O)(=O)c1cccc(NC(=O)N2CC3CC4CC(C3)CC2C4)c1 +CCOC(=O)c1c(CSc2nnnn2C)nc2ccccc2c1C +Nc1ccc(Cl)c(C(=O)NCC2CCCC2)c1 +CCc1sc(-c2nnc(CSc3nnc(C)s3)o2)cc1C +CCc1nnsc1C(=O)NCc1cccc(OC)c1OC +Cc1ccc(-c2ccc(C#N)c(=O)n2CC2CCCO2)cc1 +COc1ccc(Cl)cc1Nc1ccnc2c1c(=O)n(C)c(=O)n2C +CCOC(=O)c1cncc(NC(C)C(=O)OC)c1 +O=C(Nc1ccccc1NCc1nccn1C(F)F)c1ccccc1 +CCS(=O)(=O)N1CCN(C(=O)CCO)CC1 +NS(=O)(=O)c1cnc(N2CCCC2c2cccs2)s1 +Nc1c(C(=O)Nc2ccccc2F)nnn1Cc1ccc(F)cc1 +CCn1cnc2c(cnn2-c2ccc(C)cc2C)c1=O +CCOC(=O)c1c(NC(=O)c2cc(CC)on2)sc(C)c1C +O=C(c1cnc(C2CC2)nc1)N1CCN(CC=Cc2ccccc2)CC1 +Cc1ccccc1CN(C)C(=O)NCCN(C)C(=O)OC(C)(C)C +Cc1cccc(-n2ccnc2SCC(=O)NCCO)c1C +CCOC(=O)c1sc(NC(=O)Cn2ccnc2)cc1C +Cc1nc(C(=O)Nc2cccnc2-n2cccn2)ccc1C#N +Cc1cccc(C2CCCN(C(=O)c3cccnc3)C2)n1 +Cc1occc1-c1nnc(SC(C)C(N)=O)n1-c1ccccc1 +COc1cc(N)ccc1NC(=O)c1ccc(OCC(C)C)cc1 +CCCNC(=O)C1CCN(S(=O)(=O)c2cccc(C#N)c2)CC1 +Cc1sc2ncnc(N3CCC(C(=O)N4CCCC4)CC3)c2c1C +COc1ccncc1NC(=O)Cc1ccc(F)c(F)c1 +Cc1nnc(NCc2c(F)cccc2Cl)s1 +COc1ccccc1-n1nc(CC(C)C)nc1CCc1cnn(C)c1 +CCn1c(-c2ccccc2)nnc1S(=O)Cc1ncc(C)o1 +CC(C)Nc1cccc(CNC(=O)c2cccc(C#N)c2)c1 +COc1ccc2c(=O)n(CCOc3ccc(N)c(C)c3)ccc2c1 +O=C(COC(=O)c1ccc(F)cc1F)NCc1ccc2c(c1)OCO2 +Cc1ncnc2c1CCN(C(=O)c1ccc3c(c1)OCO3)C2 +COC(C)(C)c1noc(Cc2ccn(-c3ccc(F)cc3)n2)n1 +CC(C#N)(NC(=O)CN1CCN(C(=O)c2ccccc2)CC1)C1CC1 +CC(C)n1nc(C(=O)NC2CCC(O)CC2)c2ccccc2c1=O +CCCn1nc(-c2nc(-c3ccc(Cl)cc3)no2)ccc1=O +COc1ccc(C(=O)N2CCCC2c2n[nH]cc2-c2ccncc2)cn1 +Cc1cc(C)cc(NC(=O)CCc2c(C)nc(C)[nH]c2=O)c1 +Cc1ccc(NC(=O)C(C)S(=O)(=O)c2nccn2C)c(C)c1 +O=C(NCc1ncc[nH]1)Nc1cccc(Cl)c1SC(F)F +O=C1NCCN(C(=O)c2cc3ccccc3oc2=O)C1c1ccccc1 +CNC(=O)c1ccc(OC)c(NCc2nc(-c3ccccc3)no2)c1 +Cc1ccsc1CN(C(=O)NC1CC1)C(C)C +C=CCn1nnc(NC(=O)c2ccc(Cl)cc2Cl)n1 +Cc1cccc(C(=O)Nc2ccc3c(c2)COC3)c1 +CCCCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +O=C(CC1CSc2nccc(=O)n21)NCc1c(F)cccc1F +CCOc1ccc(OCC(=O)N2CCC(CO)C2)cc1 +CC(C)CCNC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +CCCc1nnsc1C(=O)Nc1nnc(-c2ccccc2OC)o1 +O=C(NCCc1ccc2c(c1)CCO2)NC1CCCCC1CO +O=C(COC(=O)c1cc(-c2ccco2)[nH]n1)Nc1ccc(Cl)cc1 +Cc1occc1C(=O)Nc1sc2c(c1C#N)CCC(C)C2 +Cc1ccccc1Nc1nccc(N(C)C)c1C#N +COC(=O)Cc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1 +CCc1nc2nnc3c(=O)n(C(C)c4ccc(F)cc4)ccc3n2n1 +CC1(NS(=O)(=O)Cc2ccon2)Cc2ccccc2C1 +O=C(CCCn1cncn1)Nc1cnn(-c2ccccc2F)c1 +COCc1nc(C)c(C(=O)N(c2ccccn2)C2CCCC2)s1 +CCc1ccccc1OCCC(=O)N(C)CCO +C=CCNC(=O)c1cccc(S(=O)(=O)NCc2ccccn2)c1 +COCc1cccc(NC(=O)c2cccc(-c3nnco3)c2)c1 +C=CCNC(=O)C1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1 +CC(NC(=O)N(C1CC1)C(C)C(C)C)c1ccc(-n2cncn2)cc1 +CC(=O)Nc1ccc(F)c(NC(=O)N2CCOCC2CC(C)C)c1 +CC(=O)N1CCc2cc(C(=O)OCCC(N)=O)ccc21 +COc1ccc(CCC(=O)Nc2ccc(NC(C)=O)cc2)cc1 +COc1cccc(C2CCCN2C(=O)c2nn(C)c3c2CCCC3)c1 +CCC(C)OC(=O)Cn1cnc2c(cnn2C)c1=O +O=C(NCCc1cccs1)c1ccc(-n2ccnc2)cc1 +O=C(Nc1ccccc1OCC1CC1)c1cnn(-c2ccccc2)n1 +CCn1cc2c3c(cccc31)CN(C(=O)c1cccs1)CC2 +CCS(=O)(=O)N1CCN(CCCCOC)CC1 +CCc1ccc(OC(C)C(=O)Nc2nccs2)cc1 +Cn1ccsc1=NC(=O)c1ccc(CN2CCCC2=O)cc1 +C#Cc1cccc(N(C)S(=O)(=O)CC2CCCCO2)c1 +Cc1cc(C)c(C(=O)NCCc2noc(C3CCCO3)n2)c(=O)[nH]1 +Cn1cc(Br)cc1C(=O)Nc1ccccc1C#N +CC(C)Sc1nnc(N2CCCCC2)n1C1CC1 +O=C(NCc1cscn1)c1ccc(N2CCCS2(=O)=O)cc1 +COC(=O)c1ccsc1NC(=O)c1cncc(Br)c1 +CCOc1c(C)cnc2c1c(=O)n(Cc1cccc(F)c1)c(=O)n2C +CCc1ccc(NC(=O)c2ccc(OCC(N)=O)c(OC)c2)cc1 +Cn1cc(CNC(=O)CCCSc2ccccc2)cn1 +Cc1cccc(OCC(=O)Nc2noc(-c3ccc(F)cc3)n2)c1 +COc1cccc(OC)c1OCC(=O)N1CCNCC1 +Nc1ccc(-c2nc3cc(Cl)ccc3o2)c(O)c1 +CSc1ccc(CNC(=O)c2noc(-c3ccc(C)cc3)n2)cc1 +Cc1ccc2nnc(C(=O)N(C)Cc3ccco3)nc2c1 +O=C(CCc1ccccc1)Nc1cc(-c2ccncc2)n[nH]1 +CSc1cccc(NC(=O)Cn2nnc3ccccc3c2=O)c1 +CC(C)(C)NC(=O)c1cccc(NC(=O)C2CCCC2)c1 +COC(=O)CCN(C)S(=O)(=O)c1ccc(C)c(C)c1 +O=C(Cc1n[nH]c(-c2cccnc2)n1)Nc1ccccc1Cl +COc1ccc(OC(=O)CC2c3ccccc3C=CN2C(C)=O)cc1 +Cc1c(C(=O)OC2CCCCC2)sc2ncnc(N)c12 +COC(=O)CCn1c(=O)cc(C(F)F)c2cn(C3CCCC3)nc21 +CC(C)CCCNC(=O)Nc1ccc(F)cc1C#N +NC(=O)c1ccccc1OS(=O)(=O)c1ccccc1 +CCCOC1CCCN(C(=O)Cn2nc(C)c3ccccc3c2=O)C1 +Nc1n[nH]cc1S(=O)(=O)N1CCCCC1CO +O=C(NCCCn1cccn1)NCC1(c2ccccc2)CC1 +COC(CNS(=O)(=O)c1cccc(F)c1)c1ccccc1 +Cc1nn(C)cc1C(C)n1ccnc1-c1coc(-c2ccccc2)n1 +CCOc1cc(C(=O)NCc2ccc(C)cc2)ccc1OC +CN(c1ccccn1)S(=O)(=O)c1c(Cl)cccc1Cl +CS(=O)(=O)NCCCc1cccc(Br)c1 +CCOC(=O)C(C)NC(=O)c1ccc2c(c1)CCC(=O)N2 +COC(=O)Nc1ccccc1C(=O)N(C)Cc1ccc(C)s1 +CCOC(=O)CN(C)C(=O)Nc1sc(C)c(C)c1C#N +Cc1ccc(C)c(NC(=O)C(C#N)Cc2cccnc2)c1 +O=C(NCc1cc2ccccn2n1)c1cnc2ccccc2n1 +CC(Oc1ccc(F)cc1)C(=O)N1CCC(O)C1 +COCCC1(C(=O)Nc2cc(C)cc3cccnc23)CC1 +CC(Sc1ccc(F)cc1)C(=O)Nc1ccccc1C#N +CN1C=CC=CC1=C1N=C(c2ccc(Br)cc2)OC1=O +O=C(Nc1ccccc1Br)c1ccnc(OC2CCC2)c1 +CCc1nc(C(C)NC(=O)c2sccc2C)cs1 +CC(=O)c1cc2c(cc1NC(=O)C1(C)CC1(Cl)Cl)OCO2 +Cc1ncc(CN2CCOC(C#N)C2)n1-c1ccccc1 +COc1cccc(C(=O)Nc2ccccc2N2CCOCC2)c1 +CCN1CCN(C(=O)CN2C(=O)COc3ccccc32)CC1 +Cc1noc(C)c1CNc1ccc2sccc2c1 +Cc1cccc2cnn(CCC(=O)NCCn3cc(Cl)cn3)c12 +Cc1ccc(CC2CCCN2C(=O)c2ccc(-n3ccnn3)cc2)cc1 +Cc1cc(C)c(NC(=O)CCSc2ccccc2)c(C)n1 +CC1CCC(N(C)S(=O)(=O)c2ccc(F)cc2F)CC1 +CCOc1ccccc1NC(=O)c1cnc(C)s1 +CCC1CCCCN1C(=O)NCc1cnc(C)s1 +O=C(NCc1ccco1)c1cc2ccc(O)cc2oc1=O +COc1cccc(-c2cc(C(=O)NCC3CC4C=CC3C4)[nH]n2)c1 +CCOC(=O)CC(C)CNC(=O)C1Cc2ccccc2N1C(C)=O +O=C(c1cnccn1)N1CCc2c(CN3CCOCC3)cncc2C1 +OCC(O)C(O)C(O)c1nc2ccccc2s1 +CCCN(CCC)C(=O)c1ccc(NC(=O)N2CCNC(=O)C2)cc1 +CCS(=O)(=O)N1CCCC(C(=O)NCC2CC2C)C1 +CCCCOc1ccccc1-c1cc(CO)c(=O)[nH]n1 +CCn1cc(-c2nnc(SCc3cc(=O)[nH]c(CO)n3)o2)cn1 +CCCCNC(=O)N1CCC(Cn2cc(-c3ccccn3)nn2)CC1 +CC1CCN(C(=O)c2nc[nH]c2C(=O)NCc2ccccc2)CC1 +O=C(NCc1cc(F)ccc1Br)Nc1cn[nH]c1 +CNC(=O)c1snc(-c2c(Cl)cccc2Cl)c1N +CC(=O)N(CCCNC(=O)c1ccc(F)c(F)c1)C(C)C +COC(=O)c1ccc(C(=O)N(C)C2CCCC2)s1 +Cc1cc(F)ccc1NCC(=O)N1CCCCCC1 +CCCCNC(=O)CN1C(=O)Cc2cc(C)ccc21 +CCC(C)C(NC(=O)Cn1nnc(-c2ccccc2)n1)C(N)=O +C=C(C)CN(CC)C(=O)c1ccc2nc(C)c(C)nc2c1 +CC(C)c1nc2ccccc2n1CC(=O)N(C)Cc1ccccc1 +O=C(CCc1ccccc1)N1CCN=C1c1ccccc1 +Cc1ccc(C(O)C(=O)Nc2ccccc2)cc1C +Cc1nc(C(=O)NCc2ccccc2Cl)cc(-n2cccn2)n1 +Cc1ccc2cc(CCNC(=O)Cc3cccs3)c(=O)[nH]c2c1 +O=C(CSc1nc(=O)n2ccccc2n1)Nc1ccc(F)cc1 +COc1ccc(-n2nnnc2SCCCC#N)cc1 +CCC(C)N(C)C(=O)c1cnc2c(c1)c(C)nn2C +FC(F)(F)c1nnc2cc(Br)ccn12 +CN1CCN(S(=O)(=O)c2cccc(NC(=O)c3ccoc3)c2)CC1 +COc1ccc(-c2cc(CO)nn2C)cc1C(C)C +Cc1cc(NC(=O)c2cccc(F)c2)sc1C(=O)NCC(C)O +Cc1cc(=O)c(C(=O)NCC2CCOC2)nn1-c1ccccc1F +CCC(C#N)Oc1cccc(CNC(=O)c2c(F)cccc2F)c1 +CCC(Oc1ccc2c(c1)OCO2)C(=O)Nc1c(C)cccc1C +NC(=O)C1CCN(C(=O)COCc2ccccc2Cl)C1 +CCNC(=O)COc1ncnc2c1cnn2-c1cc(C)cc(C)c1 +CCCNc1ccc(S(=O)(=O)NC(C)CC)cn1 +O=C(Nc1ccc2c(c1)OCCO2)c1cnc(N2CCCC2)nc1 +COCCn1c(SC(C)C(=O)N(C)c2ccccc2)nc(C)c1C +COc1ccccc1OC1CCN(C(=O)c2cc[nH]c2)CC1 +O=C(NCCc1csc(-n2cccn2)n1)C1CCCC1 +COCCc1nc2sc3c(c2c(=O)[nH]1)CCC3 +O=C(CCc1cccs1)Nc1ccc(F)cc1F +Cc1ccc(C)c(C(=O)Cn2nnn(-c3ccccc3)c2=O)c1 +CC(NC(=O)c1cccs1)C(=O)NCCOc1ccccc1 +COC(=O)C1=C(C)C(C(=O)CN2CCCC(C(F)(F)F)C2)=NC1C +NC(=O)Nc1ccc(Oc2c(F)c(F)c(F)c(F)c2F)cc1 +Cc1csc(NC(=O)NC(c2ccc3c(c2)OCCO3)C2CC2)n1 +CC(C)(CNC(=O)c1cnc(C2CCCO2)s1)Cc1ccccc1 +CCC(CC)NC(=O)CSc1ccc(N)nc1 +Cc1onc(-c2nc(C3CC3)nn2-c2cccc3cccnc23)c1CO +COc1cccc(CN2CCOC(C)(c3ccccc3)C2)c1OC +Cc1ccc(C(=O)NCCCc2cn[nH]c2C)cc1F +CC(C)n1c(-c2cn[nH]c2N)nc2c(F)cccc21 +CCOC(=O)N1CCN(CC(=O)NC2CCCCC2C)CC1 +CNC(=O)c1ccc(NCC(=O)Nc2ccc(F)cc2)cc1 +CCC(=O)Nc1ccc(O)c(C(=O)Nc2cccc(COC)c2)c1 +Cc1[nH]ncc1S(=O)(=O)NC(C)c1ccccc1Br +Cc1cc(Br)ccc1N(CCC#N)CCC#N +O=C(Cc1cccc(O)c1)Nc1ccc(-n2cnc3ccccc32)cc1 +CCOC(=O)C(O)c1nc2ccc(OC)cc2n1C +N#Cc1cccc(C(=O)N2CCCC(O)(CO)CC2)c1 +Cc1ccc(C(CNC(=O)c2cc(C)on2)OCCO)cc1 +Fc1ccc(C2(c3nc(-c4ccccn4)no3)CCOCC2)c(F)c1 +CC(C)CC(C#N)NC(=O)c1cccc(NC(=O)NC(C)C)c1 +NC(=O)Cn1cc2c(n1)C(NC(=O)c1cccc(Cl)c1)CCC2 +CC(O)c1cc(Cl)ccc1OCCc1cccnc1 +COC(=O)c1ccc(NC(C)c2ccc3c(c2)NC(=O)CO3)nn1 +CS(=O)(=O)NCC1CCCCN1C(=O)c1ccoc1 +CCC(=O)N1CCN(Cc2nnnn2-c2cccc(F)c2)CC1 +CCOC(=O)c1c(C)[nH]c(C(=O)N(C)C(C)c2cccs2)c1C +N#Cc1c(COC(=O)c2ccc(-n3cncn3)nc2)cn2ccccc12 +COc1ccc(-c2[nH]c(=O)c(C#N)c3c2CCC3)cc1OC +Cc1c(C)c2ccc(OCC(=O)NCc3ccncc3)cc2oc1=O +CCNC(=O)NC1(C(=O)N(C)CCc2ccccc2)CCCC1 +O=C(CCC(=O)c1ccc(F)cc1)OCC(=O)N1CCCC1 +O=C1CSc2ccc(C(=O)Nc3nc(C4CC4)cs3)cc2N1 +Cc1cc(NC(=O)NC2CCSc3ccc(Cl)cc32)n(C)n1 +Nc1onc(C2CC2)c1-c1ccc(OC(F)F)cc1 +Cc1ccc(CNc2ncnc(N(C)c3ccccc3)c2N)cc1 +CC(C)(C)n1nc2c(c1-n1cccc1)CN(C(=O)C1CC1)C2 +CCCS(=O)(=O)N1CC2CCC(C1)N(Cc1cscn1)C2=O +Cc1ccc(S(=O)(=O)N2CCCC(C#N)C2)cc1 +COC(=O)N1CCC(NC(=O)c2ccc3ccccc3n2)CC1 +CCc1noc(C)c1C(=O)NC(CC(=O)OC)c1ccc(C)cc1 +O=C(NCc1cccs1)C1(c2ccc(F)cc2F)CCOCC1 +CCCc1cc(C(=O)N2CCN(C(C)=O)CC2)[nH]n1 +CCc1noc(C(C)N2CCN(CC(=O)NCc3ccco3)CC2)n1 +Fc1ccc2ncnc(NCc3ccc(Cn4ccnc4)cc3)c2c1 +O=C(Nc1ccnn1C1CCCC1)c1ccc(NC(=O)C2CC2)s1 +Cc1cc(C(=O)Nc2cc(Cl)cc(Cl)c2)n(C)n1 +O=C(Cc1ccc2ccccc2c1)Nc1cnn(CC2CCCO2)c1 +Cc1nc(C2CCCN(C(=O)c3cc(C4CC4)[nH]n3)C2)no1 +CC(C)(CNC(=O)c1cccc(S(C)(=O)=O)c1)c1ccncc1 +CC(C)NC(=O)c1cn(C2CCN(C(=O)C(C)(C)C)CC2)nn1 +Cc1c(F)cc(C#N)cc1NCC(=O)NCCC(C)C +CC(CO)NC(=O)CCNC(=O)c1ccc(Br)cc1 +COc1cccc(C(O)CNC(=O)c2ccccc2)c1 +CCN(C)C(=O)C(C)NS(=O)(=O)c1ccc(Cl)cc1 +CC(C)(C)OC(=O)Nc1cccc(C(=O)Nc2ccncc2)c1 +O=C(Nc1ccc2c(c1)CCCO2)NC1CCCCC1O +O=C(CSc1nnc2n1CCCCC2)c1ccc2c(c1)CCC2 +Clc1ccc(Cl)c2c1CCNC2C1CNC1 +Cc1ccc(S(=O)(=O)N2CCNC(=O)C2(C)C)cc1C +Cc1ccc(-c2cc(C(=O)NCC(C)C)n[nH]2)s1 +CC(C)c1cc(NC(=O)C2CCC(=O)N(C)C2c2cccs2)[nH]n1 +Nc1cccc(CC(=O)Nc2ccc3c(c2)OCCO3)c1 +c1cncc(CSc2cc(N3CCCC3)ncn2)c1 +COc1ccc2c(CC(=O)NCCCC(N)=O)coc2c1 +CCCc1cc(C(=O)N2CCN(CC(=O)N3CCCC3)CC2)no1 +COCC(C)NC(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +COC(=O)c1cc(CNC(=O)C(OC)c2ccccc2)oc1C +COc1c(C)cnc(CNC(=O)c2cnc3c(c2)c(C)nn3C)c1C +Cc1cc(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)c(C)o1 +COc1ccc(OC2CCN(C(=O)c3cnc(C)s3)CC2)cc1 +Cc1c(C(C)NC(=O)NCCCO)oc2ccccc12 +Cc1csc(CN(C)Cc2cccc3c2OC(C)(C)C3)n1 +CCOc1ccc(NC(=O)c2cnccn2)cc1Cl +Cc1cc(-c2cnc(C)nc2C2CCN(S(C)(=O)=O)CC2)on1 +Cc1c(Cl)c(C(=O)N2CCN(c3cccnc3)CC2)nn1C +CCN(CC)C(=O)CNC(=O)Nc1ccc(C(=O)NC(C)(C)C)cc1 +Cc1noc(C(C)OC(=O)c2ccc(Cn3ccccc3=O)o2)n1 +Cc1nc(-c2cccc(Br)c2)ccc1C(=O)N(C)C(C)C +CCCOc1ccc(C(=O)N2CCC2)cc1OCC +CC(NC(N)=O)C(=O)NCCc1nc2ccccc2[nH]1 +CCCNC(=O)C1CCN(S(=O)(=O)c2ccc(OC)cc2)CC1 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc2nccnc2c1 +COc1ccc(S(=O)(=O)NCCCn2cccn2)cc1C +N#Cc1ccc(Cn2c(=O)ccc3cc(F)ccc32)cc1 +Cc1cc(S(C)(=O)=O)ccc1NC(=O)C(C)OCCC(C)C +COc1cc(C(C)=O)ccc1OC(=O)c1coc(-c2ccccc2)n1 +Cc1nnc(SCC(=O)Nc2ccc(OC(F)(F)F)cc2)n1N +COc1ccc(CSc2ccc(-n3ccnc3)nn2)cc1 +COc1ccc(NC(=O)c2cnc(N3CCCC3)nc2C)cc1OC +CC(C)c1nc(C2NC(=O)c3ccccc3N2C)cs1 +CC(Sc1ncccn1)C(=O)Nc1ncc(Cl)cc1Cl +CC(C)c1n[nH]c(NC(=O)c2ccn(-c3ccccc3)n2)n1 +CN(CC(=O)NC1CCOCC1)S(=O)(=O)c1ccccc1F +CCOCc1ccccc1CNC(=O)c1cc(F)cc2[nH]cnc12 +CC(C)(C)CN1CCCC(O)(CNCc2cnc3ccccn23)C1=O +Cc1c(Cl)cccc1C(=O)N1CCc2c(nc(N)[nH]c2=O)C1 +CCOC(=O)c1ccc2[nH]c(CSc3ncn[nH]3)cc(=O)c2c1 +CCc1nc(CC(=O)Nc2cc(-c3cccs3)ncn2)cs1 +COC(=O)N1CCC(NC(=O)C2C3CC4CC(C3)CC2C4)CC1 +COc1cc(-c2ccc(=O)n(CC(N)=O)n2)cc(OC)c1OC +CCNC(=O)c1ccc(CNC(=O)Nc2ccc(OC)cc2)cc1 +Cc1ccc(C)c(NC(=O)C(C)NC(=O)Nc2ccccc2)c1 +Cc1nc(-c2cccc(C(=O)Nc3cc(F)ccc3F)c2)no1 +CC(=O)NCCC(=O)Nc1ccc(OC(F)F)c(Cl)c1 +N#CCCn1c(C(F)(F)F)nc2ccc(F)c(F)c21 +Cn1nccc1CN1CCOC(c2ccccc2Br)C1 +CN(C)c1ccccc1C#CCNS(=O)(=O)N(C)C +CNC(=O)C(NC(=O)c1ccc(C#N)cc1)c1ccccc1 +Cc1cc(C)n2c(SCCC(N)=O)nnc2n1 +O=C(c1ccco1)N1CCN(c2cc(=O)n3ccccc3n2)CC1 +CCc1nc(CNc2ccc(C)c(F)c2)cs1 +CCCn1nc(C(=O)NCc2sccc2C)ccc1=O +COc1ccc(NC(=O)c2cncc(Br)c2)c(N)c1 +COc1ccc(-c2noc(CCc3nc(C)no3)n2)c(OC)c1 +COc1cccc(C(=O)N2CCSc3ncccc32)c1F +CN(Cc1ccccn1)C(=O)Cc1coc(-c2ccc(Cl)cc2)n1 +Cc1cc(F)ccc1CCNC(=O)NCc1ncccc1C +N#Cc1ccccc1NC(=O)CCc1ccccc1F +COC(=O)NC(Nc1ccc(C)cc1C)C(=O)c1ccccc1 +CCC(CO)NC(=O)c1nc(-c2ccccc2)oc1C(F)(F)F +NC(=O)CN1CC2(CCC1=O)CCN(C(=O)c1cccc(F)c1)CC2 +CC(CC(N)=O)Nc1cc(C(F)(F)F)nc(-c2ccccn2)n1 +CCOc1ccccc1NC(=O)CSc1ncccn1 +Cc1cccc(NC(=O)CCNC(=O)C2CCC2)n1 +Cc1c(C)c(C)c(S(=O)(=O)Nc2cccn(C)c2=O)c(C)c1C +Cc1ccc(-c2cc(NC(=O)C3COc4ccccc4O3)on2)cc1 +CC(C)n1cc2cc(NC(=O)NC3CCCC4OCCC34)ccc2n1 +O=C(NCc1nnnn1-c1ccc(Cl)cc1)Nc1ccc(F)cc1 +O=C(Cc1c(F)cccc1F)OCC(=O)N1CCc2ccccc21 +Cc1ccc(-c2cc3[nH]c(C(C)N)cc(=O)n3n2)cc1 +COc1ccc(-c2csc3ncn(CC(N)=O)c(=O)c23)cc1OC +COC(=O)CNC(=O)c1cc(-c2ccccc2)nn1C +O=C(CC1CC2CCC1C2)N(CCO)C1CCCC1 +N#CC1(C(=O)NCCc2c[nH]c3ccccc23)CCCC1 +CCOc1ccc(C(O)Cc2nc3ccccc3n2C)cc1 +Cc1ccc(Cl)cc1NC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1cc(NC(=O)c2cccnc2)n(-c2ccc(C(F)(F)F)cn2)n1 +Cc1nn(-c2ccccc2)c2nc(C3CC3)nc(N3CCCC3)c12 +Cc1cccc(OCC(=O)NCC(C)(C)N2CCOCC2)c1 +COCCNC(=O)C1CN(c2nc3ccccc3s2)C1 +CCc1nc2ccccc2c(=O)n1-c1ccc(OC)cc1 +O=C(NCC1COc2ccccc2C1)C1CCCN1c1nccs1 +Cn1ncc2c(NCc3nc(C(F)(F)F)cs3)ncnc21 +Cc1ccc(NC(=O)c2ccco2)cc1S(=O)(=O)N1CCCCC1 +CN(C)c1ncc2c(n1)CN(CCc1ccccc1F)C2=O +Cc1cccc(NC(=O)c2cccn2Cc2noc(C)n2)c1 +COc1ccc(OC)c(S(=O)(=O)Nc2nccs2)c1 +CCOc1ccc(C(=O)Nc2ccc(N3CCCC3=O)cc2)cc1 +Nc1ccc2c(c1)N(CCc1ccncc1)CCS2 +CS(=O)c1ccc(C(=O)Nc2ccc3c(c2)NC(=O)CS3)cc1 +O=C(NCc1cccs1)c1nn(-c2ccccc2Cl)nc1CO +Cc1cc(C(=O)Nc2nc(C(C)C)cs2)c(C)o1 +COCC(NC(=O)c1sc2ccccc2c1C)C(N)=O +O=C(c1cc2c(s1)CCCC2)N1CCCN(c2cccnn2)CC1 +Cc1cc(=O)c(O)c(CN2CCN(S(C)(=O)=O)CC2)n1C +O=C(NCCN1CCOCC1)Nc1ccccc1Cc1ccccc1 +CCC(CC)C(=O)Nc1ccc2c(c1)OCCCO2 +O=C(CSc1nnc(-c2ccncc2)o1)NCc1ccc(F)cc1 +CC(=O)Nc1ccc(C)c(NC(=O)NCC(C)(C)c2ccncc2)c1 +CC(Cc1ccco1)NS(=O)(=O)c1ccc2c(c1)CCO2 +CC(C)(C)NC(=O)c1cccc(NC(=O)CNC(=O)C2CCCC2)c1 +COc1cccc(NC(=O)Cc2c(C)nc3ncnn3c2C)c1 +Cc1cc(C(C)NC(=O)Nc2ccc3c(c2)COC3)c(C)o1 +NC(=O)c1n[nH]c2ccc(NCc3ccc(Cl)cc3Cl)cc12 +CC(NCC(=O)Nc1cc(-n2cnnn2)ccc1F)c1ccncc1 +Cc1nccnc1S(=O)CC1CCN(C(=O)OC(C)(C)C)C1 +O=C(NCc1nc2ccccc2n1CCc1ccccc1)C1CCCO1 +COc1ccnc(NC(=O)c2ccc(Cl)cn2)c1 +O=C(c1cc2ccccc2[nH]1)N1CCCC(C(=O)N2CCCC2)C1 +COc1ccc(-c2[nH]c(=O)oc2-c2ccc(OC)cc2)cc1 +CC(NC(=O)NCC1=COCCO1)c1cccc(Cl)c1Cl +O=C(CC1CCc2ccccc21)NCCn1cccc1 +COCC(C)OC(=O)C1CCCN(C(=O)Nc2ccccc2F)C1 +CCN(CC(=O)OC)C(=O)CCc1nc(C)no1 +O=C(COc1ccccc1F)NCc1nc(-c2cccs2)no1 +Cn1cnc2c1C(C(=O)NC1CCCC1)N(S(C)(=O)=O)CC2 +Cc1ccc(CNS(=O)(=O)Cc2cccc(F)c2)c(C)c1 +O=C1CCCC1CCn1c(=O)cnc2cc(F)c(F)cc21 +CCC(C)Oc1ccc(NC(=O)C2CCCN2C(=O)C(C)C)cc1 +Cc1ccc(CN(C(=O)c2ccc(F)nc2)C(C)C)s1 +CCc1ccc(NC(=O)Cn2ccc(C(=O)OC)n2)cc1 +CCOc1ccc(C(=O)NCCc2nc3ccccc3[nH]2)cc1 +CNC(=O)c1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +COCC(=O)N1CCC(Oc2cccc(F)c2)CC1 +Cc1ccccc1CN(C)C(=O)C(C)Sc1nnc(C2CC2)n1C +CC1Cn2c(-c3ccccc3Cl)nnc2S1(=O)=O +Cc1ccc(CN(Cc2ncc(C)o2)c2ccc(F)cc2)o1 +CC(=O)N1CCc2cc(Nc3ccccc3F)ccc21 +O=C(NCc1ccncc1)c1cc2occc2n1Cc1ccccc1F +Cc1ccccc1C(=O)Nc1cnc(N2CCCCC2)nc1 +O=C(CCn1ccc2ccccc21)Nc1nc(-c2cccnc2)cs1 +CCn1c(SC(C)C(=O)N2CCc3ccccc32)nnc1C1CC1 +Cc1ncsc1CCOC(=O)c1ccc(C(F)(F)F)nc1 +CC1Cc2ccccc2N1C(=O)CNC(=O)c1cccs1 +Cn1cnnc1CNCC(O)c1ccccc1Cl +CC1Cc2ccccc2N1C(=O)NCc1cc[nH]n1 +COCC1(O)CCN(C(=O)Nc2cc(Cl)ccc2C)CC1(C)C +CC(OC(=O)c1ccc[nH]1)C(=O)Nc1cc(F)ccc1F +Fc1cccc(-c2nn3c(CN4CCOCC4)nnc3s2)c1 +Cc1cc(C(=O)N2CCCC2)c(C)n1Cc1ccc(F)cc1 +O=C(Cc1cccs1)N1CCN(c2ccccc2F)CC1 +CCC(C)NC(=O)C1CCN(C(=O)c2ccccc2Cl)CC1 +Cc1ccc(C(=O)N(C)C)cc1OC(=O)Cc1cccc(F)c1F +COc1ccc(-c2noc(Cn3nc4ccccn4c3=O)n2)cc1 +CCCc1cc(C(=O)N2CCCCC2CO)sc1C +O=C(COc1cccc2c1CCC2=O)Nc1ccccc1OC(F)F +CCC(C(=O)c1ccc2c(c1)NCCO2)N1CC(C)OC(C)C1 +CC(=O)Nc1cc(NC(=O)N(CCO)Cc2ccccc2)ccc1F +COc1ccnc(NC(=O)CCCNC(=O)c2cccnc2)c1 +CN1CCn2c(cnc2C(=O)NC2CCCCC2)C1 +Cc1cc(NC(=O)CCSc2cccc(Br)c2)no1 +O=C(NCc1ccccc1)Nc1cccc(Cl)c1 +O=C1CCCN1c1cccc(NCc2ccc3c(c2)OCCO3)c1 +CCS(=O)(=O)c1ccc2nc(NC3CCCCC3)sc2c1 +COc1cc(C(=O)Nc2cc(C)ccc2F)cc(OC)c1OC +CNC(=O)c1cccc(NC(=O)NC(C)Cc2ccc(C)s2)c1C +Cc1ccc(CC(=O)N2CCCCC2Cn2cccn2)s1 +CCOCCCNC(=O)C1CSc2ncc(C)c(=O)n2C1 +Cc1c(C(=O)N(C)C2CCC2)oc2c(F)cccc12 +Cc1cc(C(=O)Nc2cc(-c3ccncc3)n[nH]2)nc(N(C)C)n1 +CN(C(=O)C1CC(=O)Nc2ccccc21)C1CCCC1 +Nc1cccc(C(Cc2ccc(F)cc2)C(=O)NC2CC2)c1 +CC1CCC(Nc2ccccc2NS(C)(=O)=O)CC1 +COC1CCC(CC(=O)N(C)c2ncccc2F)CC1 +CCCN1CCN(S(=O)(=O)c2cn[nH]c2)CC1 +C=CCn1cnc2c1c(=O)n(CC)c(=O)n2-c1cccc(C)c1 +COc1cccc(C(O)c2nnc(-c3ccccc3)o2)c1OC +CSc1ccc(Cl)c(C(=O)N2CC(C(N)=O)CCC2C)c1 +Cc1sc2nc(SCC#N)n(C)c(=O)c2c1C +CCCc1cc(C(=O)N(C)CCc2noc(C(C)C)n2)n(C)n1 +COc1ccccc1N1CCN(Cc2ccc(O)cc2)CC1 +Cc1ccc2c(c1)c1nnc(-n3ccnc3)nc1n2C +c1cc(-c2noc(-c3cccnc3)n2)cc(-c2ccn[nH]2)c1 +O=C(CCCc1cccs1)Nc1ccc2c(c1)NC(=O)CO2 +Cc1ccc(C(=O)NCCN2CCCCCC2=O)cn1 +O=C1CCCN1c1ccc(NCc2ccc3c(c2)CCO3)cc1 +O=C(NCCCn1ncccc1=O)c1ccc(Br)cc1 +CCOc1ccccc1NC(=O)c1cc(C)n(CC)c1C +O=C(CCOCC1CCCO1)Nc1ccc2c(c1)oc1ccccc12 +Cc1nn(Cc2nnnn2-c2ccccc2)c(=O)c(C#N)c1C +CCOC(=O)CS(=O)(=O)c1ccc2[nH]c(=O)cc(C)c2c1 +Cc1ccc(C2(Cc3c(F)cccc3Cl)NC(N)=NC2=O)cc1 +FC(F)(F)c1cccnc1CN1CCOC(c2cccs2)C1 +Cc1ccc(CCNc2nccc(C(F)(F)F)n2)cn1 +COc1ccc(CN(C(=O)c2cccc(OC)c2OC)C2CC2)cc1 +Cc1nnc(CNC(C)c2ncc(-c3ccccc3)o2)o1 +CCOC(=O)N1CCN(c2cccc(F)c2C(C)=O)CC1 +Cc1cnn(CCCNC(=O)N2CCc3c(F)ccc(F)c3C2)c1 +COc1ccc(C2CC(O)=Nc3n[nH]cc32)cc1OCc1ccccc1 +O=C(Nc1ccccc1N1CCCC1)c1ccc(-n2ccnn2)cc1 +O=C1CC(C(=O)Nc2ccc(C(F)(F)F)cc2)c2ccccc2N1 +C#CCOC(=O)C(NC(=O)c1ccc(Cl)cc1)C(C)C +COc1ncccc1CNS(=O)(=O)N1CCCCC1 +COc1ccc(C(=O)NC(C)c2nnc3ccccn23)cn1 +CCOC(C)c1noc(CSc2nc(C)nc(C)c2C#N)n1 +CCOCC1CCCN(C(=O)Nc2ccccc2N2CCCC2)C1 +C1=C(CN2CCCCC2c2nnc3n2CCCC3)COCC1 +CC1(CNS(=O)(=O)c2ccc(F)cc2F)CCOCC1 +CC(C)CC(=O)Nc1cc(Cl)ccc1N(C)C +CCN(C(C)COC)S(=O)(=O)c1ccc(C(F)(F)F)nc1 +COc1ccc2nnc(CCC(=O)NCCC3=CCCCC3)n2n1 +Cc1cccc(-c2ccc(OC(C)C(N)=O)cc2)c1 +CC(=O)Nc1ccc(Oc2nc(C)nc3sc4c(c23)CCC4)cc1 +Cc1cc(NC(=O)Cc2noc3ccccc23)ccn1 +Cn1cc(C(N)=O)cc1C(=O)NCCNC(=O)c1ccco1 +COc1ncccc1C(=O)N1CCCC(CCO)C1 +CN(CC(=O)Nc1ccc(F)cc1)C(=O)c1ccoc1 +CCOc1ccc(-n2ncc(C#N)c2C(C)C)cc1 +C=CCn1c(SCc2nnc(-c3ccccc3)o2)nnc1C1CC1 +Cc1noc(CCCC(=O)N(C)Cc2ccccc2N2CCCC2)n1 +Cc1cc(C)c(NC(=O)Cc2csc(-c3ccoc3)n2)c(C)c1 +Cc1cc(NC2CCCC2)nc(C2CN(S(C)(=O)=O)C2)n1 +COC(=O)c1cnc(NC(=O)c2oc3ccc(OC)cc3c2C)s1 +Cc1cc(=O)n2cc(-c3ccc(Cl)cc3)nc2[nH]1 +CCn1cc(C(=O)NCC(C)N2CCOCC2)c(C(C)C)n1 +COc1ccc(C)cc1NC(=O)CCC(=O)c1ccc(F)c(F)c1 +COc1ccc(CCC(=O)Nc2nncs2)cc1OC +COC(=O)Cc1ccc(OS(=O)(=O)c2ccc(C(N)=O)cc2)cc1 +CCC(C(=O)N1CC(Oc2ccccc2OC)C1)N1CCOCC1 +CNC(=O)c1ccc(NC(=O)CNC(=O)c2cc(C)cc(C)c2)cc1 +Cc1cc(C)c(NC(=O)c2cnc(-c3ccccc3)nc2C)c(C)c1 +COc1ccc(NC(=O)NCc2nncn2C2CC2)c(C)c1 +O=C1CCN(C(=O)Nc2cccc(Cl)c2)CCN1 +CN(CC1CC1)C(=O)NCc1ccc(N2CCCC2=O)cc1 +Cc1cc(S(=O)(=O)N(CCCO)C2CC2)ccc1F +NC(=O)CCN(C(=O)c1csc(Nc2ccc(F)cc2)n1)C1CC1 +CCN(CC(C)C#N)C(=O)c1cn2ccccc2n1 +CCC(Nc1cccc(CO)c1)C(=O)Nc1cc(C)on1 +COc1cc[nH]c(=NS(=O)(=O)c2cccc3ccccc23)c1 +CCc1cc(O)n2nc(C3CCCN3C(=O)C3CCCO3)cc2n1 +Cc1cccc(-n2c(=O)[nH]c3c(C(N)=O)nc(-c4ccc(C)o4)nc32)c1 +O=C(Nc1ccccc1O)c1cc(C2CC2)nn1-c1ccccc1 +Fc1ccccc1N1CCN(Cc2ccsc2)CC1 +Cc1ccc(C)n1C(C)C(=O)N1CCC(c2nncn2C)CC1 +CC(C)N(C)C(=O)NCc1ccnc(OCC2CC2)c1 +O=C(NCc1ccc(-c2ccnc3ncnn23)cc1)c1cnccn1 +CCCn1nc(-c2ccc(OCC)c(C)c2)cc(CO)c1=O +CC(=O)Nc1cc(F)c(F)cc1NC(=O)CCc1ccc(F)cc1 +CN(C)C(=O)c1cc(O)cc(CC2CCCCC2)c1 +COc1cccc(NC(=O)CCSc2nc(C)cc(C)n2)c1 +Cc1ocnc1C(=O)NCc1cnc(OCC(C)C)c(Cl)c1 +O=C(OC1CCc2ccccc2C1)c1ccc2nncn2c1 +CCCCCN(C(=O)c1ccc(-n2nc(C)cc2C)nc1)C(C)C +COc1ccc(-c2cc3nccc(-c4ccccn4)n3n2)cc1 +CN(CCC1CCCCC1)C(=O)c1cc(=O)c2ccccc2[nH]1 +CCCN(C)C(=O)Nc1cccc2c1OCCO2 +CCNC(=O)c1ccc(C)c(NCc2ccc(F)cc2F)c1 +O=C(c1cc[nH]c1)N1CCC(Oc2ccc(Cl)cc2)CC1 +NC(=O)c1cccc(NC(=O)c2ccccc2SC(F)F)c1 +COc1ccc(-n2ccc(C(=O)Nc3ccnn3C(C)C)n2)cc1 +Cc1nccn1-c1ccc(NC(=O)c2nccnc2N)cn1 +O=C(COc1ccc(F)cc1F)NCCc1cccc(O)c1 +Cn1ccc(C(=O)Nc2nc3c(Cl)c(Cl)ccc3s2)n1 +Cc1ncc(-c2onc(C)c2C)c(-c2ccco2)n1 +Cc1ccc2nc(C)c(C)c(C(=O)NC3(C(N)=O)CCCC3)c2c1 +COC(=O)c1cc(OC)c2cc(OC)c(OC)cc2c1 +COc1cccc(C(=O)NCCNc2ccc3ccccc3n2)c1F +O=C(Cc1ccco1)N1CCCC2(CC(Oc3cccnc3)CO2)C1 +COc1ccccc1CN(CCO)C(=O)Nc1cccnc1 +CC(C)Cn1ncc(C(=O)N2CCOc3ncccc32)c1C(F)F +CC(C)OC(C)c1n[nH]c(=O)n1Cc1ccco1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)Nc1nc(C(C)C)cs1 +Cc1ccc(C)c(C(=O)Nc2ccccc2C(=O)N(C)C)c1 +CCNC(=O)CNC(=O)Nc1ccccc1SC(F)F +O=C(CSc1ncnc2sccc12)c1ccc2c(c1)OCO2 +CCc1c(C(=O)NCc2nc3ccccc3[nH]2)[nH]c(C)c1C(C)=O +O=C(Nc1ccc(Cn2cccn2)cc1)NC1CCc2ccccc21 +CCC(O)CN1CCN(C(=O)c2cccc3cccnc23)CC1 +Cc1cc(NC(=O)c2cc(C)on2)c2ncccc2c1 +Cc1nc(CC(=O)N2CCc3ccccc3C2)cs1 +O=S(=O)(Nc1c(F)cccc1F)c1ccc(O)cc1 +CC(Cc1ccc(O)cc1)NC(=O)N1CCCC1c1ccncc1 +CC(NC(=O)c1ccc2ccccc2c1)c1ccncc1 +CCn1c(SCC(=O)N2CCCC(O)C2)nnc1-c1ccco1 +COc1ccc(C(=O)CNC(=O)c2ccc(F)c(F)c2)cc1 +CCOc1cc(NS(=O)(=O)c2ccc(F)cc2C)ccc1OC +Cc1cc2cc(C)c(SCC(=O)N3CCOCC3)nc2cc1C +O=S(=O)(Cc1ccccc1)Nc1ccc2nc[nH]c2c1 +C#CCN1CCN(CCOc2cccc(C)c2)CC1 +O=C1CCc2cc(NC(=O)NCC(F)(F)F)ccc2N1 +CSc1ccc(NC(=O)c2ccc3c(c2)CCN3C(C)=O)cc1 +O=C(Nc1cc(Br)ccc1-n1cncn1)c1ccccn1 +COc1cc(NC(=O)c2ccncc2)ccc1N1CCCC1=O +COc1ccc(-c2nc3nccc(-c4ccccn4)n3n2)cc1 +CN(C)C(=O)N1CCN(C(=O)NCCCn2cccn2)CC1 +Cc1cc(CN(C)C(=O)COc2c(C)cccc2C)no1 +CCC(=O)Nc1cccc(NC(=O)N(CC)CCO)c1 +Cc1cccnc1CNC(=O)N1CCCC1CN1CCOCC1 +Cn1nnnc1COc1ccc(CC(=O)Nc2nncs2)cc1 +Cc1ccc(-c2nc(C(=O)Nc3cccn(C)c3=O)cs2)cc1 +CNC(=O)C1CCC(NC(=O)NCCOc2cc(C)cc(C)c2)CC1 +COC(=O)c1cc(-c2cn(C)nc2C)nc2c(-c3ccccc3)cnn12 +COc1ccc(C(=O)OCC(=O)Nc2cc(F)ccc2F)c(C)c1 +Cn1ccc(-c2cc(C(=O)NCCc3cccnc3)c3ccccn23)n1 +COCCN1CCN(C(=O)c2cc(-c3ccccc3F)on2)CC1=O +CCNC(=O)CSc1nnc(C)n1-c1ccc(C)cc1 +CC(C)S(=O)(=O)NCC#Cc1ccc(N2CCOC2=O)cc1 +Cc1nc(-c2noc3ccc(C(=O)NCc4cccnc4)cc23)co1 +COC(=O)c1ccc(OC)cc1NCC(=O)NC1CC1 +CNC(=O)c1cccc(S(=O)(=O)NCc2ccccc2)c1 +CC(C)n1nnnc1SCC(=O)c1ccc(F)c(F)c1 +COc1ccc(C)cc1C(=O)OC(C)C(=O)Nc1sccc1C#N +COc1ccc(-c2cc(C(=O)Nc3nccs3)no2)cc1 +O=C(NCCCC(=O)N1CCN(c2ccccc2)CC1)c1ccco1 +O=S(=O)(CCCOc1ccc2c(c1)OCO2)NC1CCCCC1 +CCNC(=O)N1CCC(Cn2c(C)nc3ccccc32)CC1 +Cc1csc(NC(=O)CSc2nnc3nc(C)cc(C)n23)n1 +CCCCOc1nc(N)nc2c1ncn2C1OC(CO)C(O)C1O +CC(C)N1CCN2C(=O)N(C3CCOCC3)CC2C1 +COc1ccc(C(=O)COc2ccc(NC(C)=O)cc2)cc1OC +CCN(CC)C(=O)CCC(=O)Nc1ccc(F)cc1Br +Cc1cc(NCCSc2nc3ccccc3o2)n2nccc2n1 +O=S(=O)(c1cccs1)N1CCN(c2ccc(Cl)cc2)CC1 +Cc1nnc(NC(=O)c2cc3ccccc3o2)s1 +CCc1onc(C)c1NC(=O)c1cc2ccc(Br)cc2[nH]1 +COc1cc(C)c(S(=O)CCc2scnc2C)cc1OC +O=S(=O)(CC(O)C(Cl)(Cl)Cl)N1CCCCC1 +CN1C(=O)N(C)C23CCCCC12N(C)C(=O)N3C +CCOC(=O)CN(C)C(=O)Cc1ccc(F)cc1F +CC(Nc1ccc(=O)n(C)c1)c1ccc(Br)cc1 +Nc1cc2c(cc1OCc1cccs1)OCCO2 +CN(Cc1ccccc1)C(=O)c1cccc(Cl)c1 +Cc1c(F)ccc2c1C(c1cncc(F)c1)NCC2 +O=C(CCC(=O)N1CCN(c2ccccn2)CC1)NCC1CCCO1 +CC1CC1C(=O)N1CCN(Cc2ccccc2)CC1 +COc1ccccc1OC1CN(Cc2cnc(-c3ccco3)nc2)C1 +CCCN(C)C(=O)C(C)NC(=O)c1ccc(Cl)cc1 +Cc1ccc(F)c(S(=O)(=O)Nc2c[nH]nc2C)c1 +NC(=O)c1oc2ccccc2c1NC(=O)C1CCCCC1 +CC(C)(C)n1nnnc1SCC(=O)c1ccccc1 +CCOC(=O)c1sc2ncnc(NCc3ccccc3)c2c1C +CC(=O)c1cccc(NC(=O)Cc2nonc2N)c1 +Cc1oc(-c2cccc(Cl)c2)nc1Cn1cnc(C2CC2)n1 +Cc1nn(C)c2cnn(C(C)C(=O)NCC(=O)N3CCCC3)c12 +Cc1ccc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)cc1N +OCc1cnc(N2CCC3(CCCCC3)CC2)s1 +CC1CCC(N(C(=O)c2ccc(-n3ccnn3)cc2)C2CC2)CC1 +O=C(COc1ccc(Oc2ccccn2)cc1)N1CCCC(O)C1 +CCN(Cc1ccccc1)C(=O)c1cn2cc(Cl)ccc2n1 +Cc1ccccc1C(=O)NC1CCN(C(=O)C2CC(=O)N(C)C2)CC1 +NS(=O)(=O)c1ccc(CC(=O)NCCc2cccc(F)c2)cc1 +Cc1nc2nc(C)c(-c3ccc(F)cc3)c(N)n2n1 +CC(OC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)C1CCCCC1 +CCCC(C)C(=O)Nc1ccc(OCc2nc(C)no2)cc1 +Cn1cc(CCNC2CCc3c(F)ccc(Br)c32)cn1 +O=C(NCCC(=O)N1CCOCC1)NCc1cccs1 +COCC(=O)N1CCCCC1c1nc(C)cc(Nc2ncccn2)n1 +NC(=O)CCNC(=O)c1cccc(NC(=O)c2ccc(F)cc2F)c1 +C=CCn1cnc2scc(-c3ccc(F)cc3)c2c1=O +COC(=O)CNC(=O)c1cc(C)nc2onc(-c3ccccc3F)c12 +CCOc1ccc(C(=O)N2CCCC(CNC(C)=O)C2)cc1 +CC1CCC(C)N1C(=O)c1cc(COc2cccc(F)c2)[nH]n1 +COc1nn(C)cc1C(=O)N1CCN(CC(O)C2CC2)CC1 +Cc1ccc(S(=O)(=O)Cc2csc(N3CCOCC3)n2)cc1 +O=C(NCc1cccc(F)c1)c1ccc(Cl)cc1 +CCCCN(C)S(=O)(=O)c1ccc(F)c(S(C)(=O)=O)c1 +CCOc1ccccc1C(=O)NCC(=O)N1CCCC1 +CCc1ccc(CN(C)Cc2snnc2C)nc1 +COc1cccc(C(=O)Nc2nc3c(OC)cccc3s2)c1 +CC(C)c1ccc(NC(=O)NCc2cnn(C)c2)cc1 +Cc1cccnc1NC(=O)Cn1ncc2c1-c1ccccc1OC2 +O=C(NC1CCCCCC1)c1cccc(NC(=O)C2CCCO2)c1 +Cc1nc2ccc(NC(=O)NCCCc3c(C)noc3C)cc2o1 +O=C(NCc1ccccc1OCCO)Nc1ccc2c(c1)CCC2 +CCC(OC(=O)C1CCN(C(C)=O)CC1)c1cccc(Cl)c1 +O=C(Nc1ccc(-n2cccn2)c(F)c1)c1cccs1 +NC(=O)c1ccc(NC(=O)CC2(n3cccc3)CCCCC2)cc1 +Cc1nc(C)c(C(=O)NCc2nn(C)c(=O)c3ccccc23)s1 +O=C(Cc1cc(-c2cccs2)on1)NCc1ccco1 +CCN1CCN(C(=O)C(C)Oc2ccc(C(C)C)cc2)CC1 +COCCCC(=O)Nc1ncc(Cc2ccc(F)cc2F)s1 +CNC(=O)CSc1cc(Cl)ccc1Cl +O=C(Cn1cnnn1)Nc1ccc(-n2cncn2)cc1 +CC(Cc1ccsc1)Nc1c(F)cc(N)cc1F +O=C(CN1C(=O)CSc2ccccc21)Nc1ccnc2ccnn12 +COc1cccc(NCc2nn(Cc3cccc(Cl)c3)c(=O)[nH]2)c1 +OCCN1CCN(c2ncnc3c2[nH]c2ccc(F)cc23)CC1 +O=c1[nH]ncc(NC2CCN(c3ccccc3)C2)c1Cl +Cc1ccc2nc(C3CN(C(=O)c4c(F)cccc4F)C3)[nH]c2c1 +O=C(c1ccc2c(c1)OCO2)N1CC2OCC(=O)N(CC3CC3)C2C1 +COC(=O)c1cccc(OS(=O)(=O)c2ccc(C#N)cc2)c1 +CC1(C)COCCN1C(=O)c1nc(C2CC2)n(-c2ccccc2)n1 +Cn1cccc1CN(C(=O)c1ccc(F)cc1F)C1CC1 +CC(=O)OC(C)C(=O)OC1CC2CC1C1CC=CC21 +Clc1cc(Cl)c2c(c1)C(c1nc[nH]n1)NCC2 +O=C(COC(=O)c1ccccc1Cl)Nc1ccc2c(c1)OCO2 +Cc1nn(C(=O)C(C)(C)C)c(C)c1S(=O)(=O)N1CCC(C)CC1 +O=C(NCc1ccncc1)c1nc2ccccn2c1-c1ccc(F)cc1 +CC(C)C(C)NC(=O)Nc1ccc(-c2nnnn2C2CC2)cc1 +Cc1nc(CCNC(=O)Nc2cccc(F)c2F)cs1 +CCn1cc(Br)c(C(=O)Nc2cccc(OC)c2)n1 +Cc1ccc(CCNC(=O)c2cnn(-c3ccncc3)c2C)cn1 +O=C(NCC(O)(c1ccco1)C1CC1)c1ccsc1 +Cc1ccsc1C(=O)OCc1cc(=O)n2ccsc2n1 +CCCOC(=O)C(C)n1nnc(C(=O)OC)c1N +CCS(=O)(=O)N1CCC(C(=O)OCC(=O)c2ccc[nH]2)CC1 +COCn1nc(CO)cc1-c1cccc(Cl)c1 +N#CCCCCS(=O)(=O)NC1CCc2ccc(F)cc21 +Cn1cc(-c2nn(-c3ccccc3Cl)c3c2CNCC3)nn1 +O=C(Nc1ccc2c(c1)COC2)N1CC2CCC1C2 +CC(NC(N)=O)C(=O)NCc1ccc(F)cc1C(F)(F)F +COCCOc1ccc(NC(=O)Cc2ccc(C)nc2)cc1F +CCNC(=O)COc1ccc(N(C)C(=O)c2ccc(C)cc2)cc1 +CC(C)(C)c1ccc(C(=O)Nc2cnn(-c3ncccn3)c2)cc1 +Cc1nn(C)c(C)c1OCc1nccn1CC(F)(F)F +NC(=O)c1ccccc1NC(=O)c1ccnc(F)c1 +CCn1cc(NC(=O)NC(C)(C)c2nc(C)c(C)s2)ccc1=O +CCc1nnc(CNC(=O)c2c[nH]nc2-c2cccc(OC)c2)s1 +COc1cc(CNc2ncccc2C#N)ccc1OCC1CCCO1 +COCC(C)Nc1ncnc(N(C)Cc2ccccc2)c1N +COc1ncccc1CNC(=O)C1Cc2ccccc2C(=O)O1 +CC(CO)NC(=O)CCOc1ccc(Cl)cc1 +COc1ccc(CO)cc1OCCc1ccc2c(c1)OCO2 +Cc1cccc(C(C)OC(=O)CCC(=O)Nc2nccs2)c1 +N#Cc1ccc(OC(=O)C2CCCN(CC(F)(F)F)C2)cc1 +CCCc1cc(Sc2ccc(N)cc2)n2ncnc2n1 +CC(CC#N)N(C)C(=O)Nc1c(F)cc(F)cc1-c1ccccc1 +COc1ccc(CCC(=O)NCc2cnc(C)s2)cc1OC +Cn1c(-c2ccccn2)nn(CCNC(=O)NC(C)(C)C)c1=O +CCn1nc(C)c(S(=O)(=O)N2CCCCC2)c1C +O=C(Nc1ccc2c(c1)OCO2)C1(n2cnnn2)CCCCC1 +CC(C)(C)CN1CC(NC(=O)Cc2ccc(O)c(Cl)c2)CC1=O +Cc1cc(SCc2ccccc2Cl)[nH]c(=O)n1 +Cc1ccccc1OCc1ccc(C(=O)N2CCOCC2)o1 +C=CCN(Cc1ccccc1)C(=O)c1ccc(C)nc1C +N#CCCCn1nnn(-c2ccccc2Cl)c1=O +N#CC(C(=O)C1CCC1)c1nc(N)nc(Nc2ccccc2)n1 +O=C(Oc1ccc(-n2cnnn2)cc1)c1cccc(Cl)c1 +CCc1nc(N2CCCC(CO)(CCOC)C2)ncc1C +O=C(CCN1CCOC1=O)NCC(=O)Nc1nccs1 +CCCSc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1 +COC(=O)c1cc(-c2cc(C)cc(C)c2OC)[nH]c(=O)n1 +COc1ccc(CNC(=O)N2CCCN(S(C)(=O)=O)CC2)cc1 +Cc1cc(C(=O)Cn2cc(C(F)(F)F)cc(Cl)c2=O)c(C)n1C +CC(Cn1cncn1)NC(=O)NCCc1cc(F)ccc1F +Cc1cc(NC(=O)Cc2ccc(F)cc2)c2ncccc2c1 +O=C(c1cc(F)cc(F)c1)N1CCCC1Cc1ccccc1 +Cc1ncnc2c1ncn2-c1ccc(C(C)O)cc1 +CCN(CC)C(=O)CSc1n[nH]c(=O)n1C1CC1 +CCc1ccc(CN(C(=O)c2cccn2C)C2CC2)cc1 +O=C(NCc1ccc(CN2CCCC2=O)cc1)c1ccoc1 +Cc1ccc(N2CCCN(C(=O)c3ccoc3)CC2)nn1 +CC(=O)Nc1ccc(OC(=O)C2CC(=O)N(CC3CC3)C2)cc1 +COc1cc(CN2CCOC3CCCCC32)cc2c1OCO2 +Cc1cc(C)c(C(=O)Nc2ccc(C#N)cn2)c(C)c1 +CCOC(=O)C1=C(N)Oc2ccccc2C1c1ccccc1 +Cc1occc1CN(C)C(=O)CCc1cccc(Br)c1 +Cn1c(NCc2ccco2)nc2c1c(=O)[nH]c(=O)n2C +Cc1ccc2ncn(CC(=O)N3CCc4ccccc43)c(=O)c2c1 +CC(C)CN1CC2CCN(C(=O)NC(C)C)CCC2S1(=O)=O +CC(C)c1nnc(COc2c(CO)cc(F)cc2CO)o1 +N#CCC(=O)NCc1ccc(Br)cc1C(F)(F)F +COc1ccc2c(c1)OCC(CNC(=O)C1CCC(O)CC1)C2 +Cc1ccc(C(=O)CCC(=O)Nc2nccs2)cc1 +Cc1ccc2cc(C(=O)NCc3cn(-c4ccccc4)nn3)[nH]c2c1 +CC1(C)CN(C(=O)c2ccccc2OCc2cscn2)CCO1 +CCOc1ccc(C(=O)Nc2ccc(NC(C)=O)cc2)cc1Cl +Cc1ccn(-c2ccccc2NC(=O)Nc2ccc3c(c2)CC(=O)N3)n1 +COCc1ccccc1NC(=O)C1(c2cccc(F)c2)CCOCC1 +COc1nccnc1NC1CCN(C(=O)COc2ccccc2)CC1 +O=C(Nc1nccs1)c1cncc(Br)c1 +O=S(=O)(Cc1cccc(Cl)c1)c1nc2cccnc2s1 +CCCCS(=O)(=O)Nc1cnn(C2CCOC2)c1 +OCC1CCCN1c1cc(NCCc2ccsc2)ncn1 +Oc1ccc(-c2csc(N3CCCCC3)n2)c(O)c1 +CCN(C(=O)c1ccncc1)c1cccc(NC(=O)c2ccncc2)c1 +Nc1cc(F)ccc1C(=O)OCC(=O)NC1CC1 +CCOC(=O)N1CCN(CC(=O)c2[nH]c(C)c(C(C)=O)c2CC)CC1 +CCc1noc(CC)c1CC(=O)NC(C1CC1)C1CC1 +CCc1onc(C)c1NC(=O)NCC(=O)NC1CCCCC1 +O=C(Cc1c[nH]c2ncccc12)NCc1ccccc1 +N#Cc1ccc(C(=O)Nc2cccc(C#Cc3ccccn3)c2)cc1 +Cc1cc(C)c(CNC(=O)NCC(O)c2ccc(F)cc2)c(=O)[nH]1 +CCCCOc1ccc(C(=O)NC(C)(C)C)cc1N +Cc1cc(N(C)Cc2csc(C(C)C)n2)n2nccc2n1 +CC1CCc2sc(NC(=O)c3ccccc3Cl)c(C(N)=O)c2C1 +COCCCNC(=O)Cn1c(=O)cnc2ccccc21 +CCn1nc(C(=O)NC(C)c2ccccc2)ccc1=O +Cc1nc(-c2cccc(=O)[nH]2)n(-c2cccc(Cl)c2F)n1 +O=C(NCc1ccc(F)cc1)Nc1c(F)cccc1F +O=C(NC1CC1)c1c2c(nc3ccccc13)CCCC2 +Cc1cc2cc(NC(=O)c3ccc4c(c3)OCCCO4)ccc2n1C +CC(C)CC(=O)Nc1ccc(NC(=O)CNC(N)=O)cc1 +O=C(C1CCOCC1)N1CCN(Cc2ccc(Cl)cc2)CC1 +Cc1cccc(C(=O)NC(C)c2cnn(-c3ccccn3)c2C)n1 +CNc1nc2c(c(=O)[nH]c(=O)n2-c2ccccc2)n1C +COCc1cccc(-c2nc(C3CCOC3)no2)n1 +O=C(CCC1CCCO1)Nc1nc(-c2ccco2)n[nH]1 +Nc1cc(-c2csc(-c3cc[nH]n3)n2)ccc1O +C=CCn1cnnc1SCc1cccc(S(=O)(=O)N(C)C)c1 +COc1cccc(-n2nnnc2SCC(=O)N2CCOCC2)c1 +CC1(NC(=O)CCc2nc(C3CC3)no2)Cc2ccccc2C1 +COc1cccc(-c2nc(-c3c(N)n(C)c(=O)n(C)c3=O)cs2)c1 +Cc1c(C(=O)NC(C)CCC2CC=CO2)[nH]c2c1C(=O)CCC2 +CC(C)CNC(=O)CSc1nnc(-c2cccc(Cl)c2)n1N +Cc1ccc(-n2nnc(CO)c2C)cc1Br +Clc1ccc(OCCOCCn2ccnc2)c(Br)c1 +Cc1ccccc1C(CC(=O)NC1(C#N)CCCCC1)NC(N)=O +O=C(Cc1ccc(NC(=O)c2cccnc2)cc1)NCC(F)(F)F +CCN(Cc1ccc(OC)cc1)C(=O)c1ccc(-n2cncn2)nc1 +CCn1cc(C(=O)NCc2ncccc2C)c(C(C)C)n1 +COc1ccc(NC(C)=O)cc1NS(=O)(=O)c1ccccc1 +CNC(=O)C(C)CN(C)Cc1ccc(C(=O)OC)c(F)c1 +CCn1c(C)nnc1SCc1cccc(F)c1 +COc1ccc(C(C)=O)c(OCc2nnc(-c3ccccc3)o2)c1 +CCN1C(=O)C(C)(C)Sc2ccc(C(C)=O)cc21 +CC1CCCN(C(=O)c2ccc(Cl)c(S(C)(=O)=O)c2)C1 +CCNc1ncnc(N(C)Cc2ccccc2)c1N +Cc1ccc(NC(=O)c2ccc(S(=O)(=O)NC3CC3)cc2)cc1F +N#CC1(C(=O)NCCNc2cnccn2)CCCC1 +COc1ccc(F)c(CNC2COc3ccccc3C2)c1 +CC(C)OCC(O)CN1CCN(c2ccccc2O)CC1 +Cc1cc(S(=O)(=O)Nc2ccn(C)n2)ccc1OC(C)C +O=C(c1csnn1)N1CCC2(CC1)CNc1ccccc12 +CCC(=O)Nc1ccc(CC(=O)NC(C)(C)CO)cc1 +OCCCc1nc2n(n1)C(c1ccccc1)CC(c1ccccc1)=N2 +CCOC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1 +Cc1ccc(C)c(OCCC(=O)NCc2nc3ccccc3[nH]2)c1 +NC(=O)c1ccc(CSc2nc(-c3cccnc3)n[nH]2)cc1 +CCC1CCC(NC(=O)Nc2ccc(CN3CCCC3=O)cc2)CC1 +CC(C)(C)C(=O)N1CCN(CC(=O)Nc2sccc2C#N)CC1 +c1ccc(CCNCc2ncc(-c3ccco3)s2)nc1 +CN(CCc1ccccn1)C(=O)c1c[nH]nc1-c1ccccc1F +COc1ncccc1CNC(=O)Nc1cc(C)nn1C +Cn1ccnc1-c1nccn1-c1ccc(NC(=O)c2cccnc2)cc1 +O=C(Cn1c(=O)oc2ccccc21)Nc1cccc(Cl)c1F +Nc1c(C(=O)Nc2ccc(F)cc2)nnn1Cc1ccccc1Cl +CC(O)CC(CNC(=O)C1CCCC1)c1ccccc1 +Cc1ccc(-n2ccnc2SCC(=O)N2CCCCC2)cc1C +O=C(NCCCn1cccn1)NCCc1ccccc1F +NC(=O)c1cccc(S(=O)(=O)Nc2cccc3ccccc23)c1 +O=C(Nc1ccc(Cl)cc1Cl)c1cnc2ccccn2c1=O +O=S(=O)(Nc1ccncc1)c1cccc(Cl)c1Cl +Cc1ccc(F)cc1C(=O)NCc1ccc(N2CCCCC2=O)cc1 +CNC(=O)NCC(=O)N1CC(c2ccccc2C)CC1C +O=C(NC(CO)c1ccccc1)c1ccc(CSc2ncn[nH]2)o1 +Cc1ccc(CN(C)CC(O)c2ccccc2F)s1 +Cc1ccc(NC(=O)c2ccc(N3CCCC3=O)cc2)c(C)c1 +CC(C)c1ccccc1NC(=O)CSc1ccccn1 +CC(=O)N(C)Cc1cccc(NC(=O)c2ccsc2)c1 +COC(=O)c1cccc(-c2ccc3nc(N)nn3c2)c1 +CNC(=O)NCC(=O)Nc1ccc(C)c(C(=O)NC(C)C)c1 +Cn1cc(C(O)CNC(=O)C(C)(C)C)c2ccccc21 +Cc1ccc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1N +COc1ccc(NC(=O)N2CCCC(O)C2)cc1OC1CCCC1 +N#Cc1ccc(NC(=O)NCCN2CCOCC2)cc1C(F)(F)F +Cc1ccn2cc(C(=O)N3CCN(c4cccc(O)c4)CC3)nc2c1 +O=C(Cc1nc2ncccn2n1)NC1CCCc2ccccc21 +CCc1cccc(OCCCC(C#N)C(=O)N2CCCC2)c1 +CN(C)S(=O)(=O)NCC(Cc1cccc(F)c1)N1CCNC1=O +CN(C)C(=O)Cc1nc(-c2ccc3ccccc3c2)cs1 +CN(C)C(=O)CNc1ccc(C(=O)N2CCCCCC2)cc1 +CCn1c(-c2ccccc2)cc(C(=O)N2CCOCC2)c1C +Cc1nc(C)c(C(=O)Nc2c[nH]cc(Br)c2=O)o1 +O=C1OCC2C(=O)N3Cc4nc5ccccc5cc4C3OCC12 +CC1CC1CNC(=O)c1ccc(-n2cnnn2)cc1 +Cc1cccc(OCCC(=O)NCc2nnc3n2CCC3)c1C +CCC(CO)NC(=O)Nc1ccc(OCC(F)(F)F)nc1 +CS(=O)(=O)c1ccc(NCC2CCCC2)c(S(C)(=O)=O)c1 +CCN(CC)c1nc(-n2cccc2)nc(-n2nnc(C(C)=O)c2C)n1 +CS(=O)(=O)NCCCSc1ncc(-c2ccccc2)o1 +COC(=O)c1cc(C(=O)OC)cc(-n2nnc(C(N)=O)c2C)c1 +CCn1cc(NC(=O)c2ccc(F)c(COC)c2)ccc1=O +CC(C(=O)NCc1ccc(-c2ccc3c(c2)CCO3)cc1)n1cncn1 +COc1ccc(O)c(C(=O)OC(C)C(=O)Nc2ccccc2C#N)c1 +CNC(=O)Cc1ccc(NS(=O)(=O)c2cccc(OC)c2)cc1 +Cc1cnc(NC(=O)C(C)Oc2ccc(F)cc2F)s1 +O=C(c1cnc2ccccn12)N1CCOC(CCc2ccccc2)C1 +COCC(=O)N(C)CC(=O)N1CCC(OCc2ccccc2C)CC1 +CC(Sc1nccc(=O)[nH]1)C(=O)Nc1ccc(C(F)(F)F)cc1 +CC(C)Oc1ccc(C#N)cc1NCc1ccccc1C#N +CCn1cc(S(=O)(=O)NCc2nc3ccccc3n2CC)cn1 +CCOC(=O)CCC(=O)Nc1ccc2c3c(c(=O)[nH]c2c1)CCCC3 +Cn1cc(C(=O)NC2CCN(c3nc4ccccn4c3C#N)CC2)cn1 +CN(C)c1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccc(F)cc1 +COc1cc(F)c(NC(=O)OC(C)(C)C)c(F)c1 +CC1(c2ccc(F)cc2)CC(=O)c2cc(O)ccc2O1 +Cc1cc(N)c2nnc(-c3ccc(F)c(F)c3)n2c1 +N#CCCSc1ccccc1NC(=O)c1cc2ccccc2c(=O)[nH]1 +Cn1cc(NC(=O)c2cccc(-n3cncn3)c2)cn1 +Cc1nn(C)c(Oc2cccnc2)c1CNc1ccc(F)cc1 +O=C(CSc1cccc2ccccc12)Nc1ccc2[nH]c(=O)[nH]c2c1 +O=C(NCc1cccc(F)c1)Nc1ccc2c(c1)COC2 +CC(NC(=O)Cc1ccc(F)cc1)C(=O)N1CCCCC1 +CCOc1ncnc2c1CN(c1ccc(C#N)cn1)CC2 +Nc1ccc(F)c(NC(=O)COc2ccc(Cl)cc2Cl)c1 +Cc1nnc(CN2Cc3ccccc3C(c3ccccc3)C2)n1C +N#Cc1c(F)cccc1N1CCN(C(=O)c2cccs2)CC1 +Cc1cc2cccc(NC(=O)CC(C)n3ccnc3)c2o1 +CCOc1ccccc1C(=O)Nc1cc(-c2nnc(C)o2)sc1C +CCC(COC)NC(=O)N1CCC(OCc2ccccc2F)CC1 +O=C1CSc2ccc(C(=O)OCc3ccccc3F)cc2N1 +COCC(NC(=O)c1cc(C)sc1C)C(N)=O +COc1ccc(Br)cc1C(=O)C1CCCCO1 +CCN(C(=O)c1cc2nc(C)ccc2o1)c1ccccc1 +CCOc1ccc(Cl)cc1NC(=O)Cn1cccnc1=O +CC1CCCCN1S(=O)(=O)c1cccc(C#N)c1 +COc1ccc(C)cc1C(=O)CCC(=O)Nc1cccc2ncccc12 +CC1CCCC(C)N1C(=O)Cn1c(S(C)(=O)=O)nc2ccccc21 +C=C(C)COc1ccc(NC(=O)c2cccnc2)cc1 +COc1ccc(N)c2c(C(=O)Nc3cccc(Cl)c3)nccc12 +COc1ccc2[nH]cc(Cc3nc(-c4ccncc4)no3)c2c1 +CC(=O)N1CC(C(=O)N2CCC3(CC2)OCCO3)C1 +Cc1nc(C(NC(=O)Nc2ccccc2C)c2ccccc2F)no1 +O=C(Nc1ccc(-n2cnc3ccccc32)cc1)C1CC=CC1 +COc1ccc(CCCNC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +CNC(=O)C1CC(=O)N(CCc2ccc(F)cc2)C1 +Cn1c(SCC2(O)CCCCC2)nnc1-c1cccnc1 +CC1CN(S(=O)(=O)N(CC2CC2)CC2CC2)C(C)CO1 +CC(O)(CNC(=O)c1cccc(F)c1)c1ccc(F)cc1F +CCCCNC(=O)NCC1CN(Cc2ccccc2)CCO1 +O=C(c1ncoc1C1CCCO1)N1CC2CCCC2C1 +Cc1cc(CC2COCC2NC(=O)c2nc3ccccn3c2F)on1 +CCCCNC(=O)c1cc(=O)c2cc(N)cc(Cl)c2o1 +COc1ccc(C(=O)CNc2nonc2C)cc1Cl +O=C(CSc1ccncc1)Oc1cc(Cl)ccc1Cl +O=S(=O)(NCc1ccc2c(c1)OCCO2)c1ccccc1 +Nc1ccc(OCc2ccccc2)c(C(F)(F)F)c1 +Cc1cc2cccc(NC(=O)c3n[nH]c4ccccc34)c2o1 +Cc1cc(C(F)(F)F)nn1C(C)C(=O)N1C(C)CCCC1C +Cc1ccc(C)c(Nc2nnc(CC(=O)N3CCCC3)s2)c1 +Cc1ccc(C(=O)N2CCCN(C(=O)c3ccc(C)s3)CC2)s1 +Cc1ccc(-n2ccnc2)c(C(=O)Nc2ccc3c(c2)COC3)c1 +Cc1c(COC(C)C)cccc1NC(=O)N1CCC(O)C1 +Cc1cccc(C)c1OC1CN(C(=O)C(O)c2ccccc2)C1 +O=C(NCCn1nc(-c2ccccc2)ccc1=O)NC1CCCCC1 +CCOCc1ccccc1CNC(=O)CN1CC(C)OCC1C +Cc1ccc(C(O)CN(C)c2ccccc2)cc1N +O=C(NCC1C2Cc3ccccc3C12)c1ccc(-n2ccnn2)cc1 +Cn1cnc(S(=O)(=O)NCC(=O)N2CCCC3CCCC32)c1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccccc1F +Cc1csc2nc(CNc3ccccc3Cl)cc(=O)n12 +Cn1c(SCc2n[nH]c(=O)[nH]2)nnc1-c1ccccc1 +CN1CCN(C(=O)C2CCN(C(=O)Nc3ccccc3)CC2)CC1 +CC(=O)N1CCCC(Cc2nccnc2-c2cccc(CO)c2)C1 +O=C(NCC(F)(F)F)c1ccc(-n2cccn2)cc1 +O=C(NC1CCCN(Cc2ccccc2)C1=O)c1ccc(F)cc1 +CCOc1ccc(N2CCN(CC(=O)Nc3ncccn3)C2=O)cc1 +CC(C)(C)NC(=O)C1CCCCN1C(=O)c1cccc2c1OCCO2 +Nc1cccc(C(=O)CCC(=O)N2CCOCC2)c1 +CC(C)OCc1cccc(CNC(=O)C2(C#N)CCC2)c1 +CCN(C)c1ncnc2c1CCN(C(=O)C1CCOCC1)CC2 +O=c1[nH]cnc2ccc(-n3c(CO)nc4ccccc43)cc12 +CCOCC(=O)NCC1(c2ccccc2OC)CCOCC1 +Cc1ccc(N)cc1NC(=O)C(C)n1cnc2ccccc21 +CCC(C)NC(=O)Cc1csc(NC(=O)NC2CCCCC2)n1 +Cc1ccc(S(=O)(=O)N(C)CC2CCCC2)s1 +CCC(NC(=O)NCc1nc(C)cs1)C(C)C +O=C(OC(C1CC1)C(F)(F)F)c1ncn(-c2ccccc2)n1 +Cc1nc2n(n1)C(C(=O)NCCc1ccccc1)CC(=O)N2 +CCOc1ccc(-c2ccc(CC#N)c(=O)n2CC)cc1 +CCCCS(=O)(=O)NC1(C(=O)OC)CCCCC1 +CC(C)C(=O)N1CCN(c2ccc(Cl)cc2)C(=O)C1C +COc1ccc(SC(C)C(=O)Nc2c(C(N)=O)n[nH]c2C)cc1 +CCOC(=O)c1cnnn1CCOc1cccc(N)c1 +CCC(C(=O)NC(C)c1ccccc1C)c1c(C)noc1C +Cn1c(=O)c(C(=O)NCc2ccc(Cl)cc2)cc2cccnc21 +CS(=O)(=O)N1CCC(NS(=O)(=O)c2ccc(F)cc2)CC1 +Cc1nc(C)c(CC(=O)Nc2ccncc2)c(=O)[nH]1 +O=C(C1CCCN1C(=O)c1nc2ccccn2n1)N1CCCCC1 +Cc1cccc(C2CN(C(=O)OC(C)(C)C)CCN2)c1 +CC(OC(=O)Cn1nc2ccccn2c1=O)c1ccc(F)c(Cl)c1 +COc1ccccc1NC(=O)C(C)OC(=O)c1cc2c(s1)CCC2 +CC(=O)Nc1ccccc1OCC(=O)Nc1ccc(C)cc1F +COCCCN(C)C(=O)c1ccc(C)c(NC(=O)c2ccco2)c1 +CCCN(C)S(=O)(=O)c1cccc(-n2cnnn2)c1 +CCOc1cccc(C(=O)Nc2ccn(Cc3ccccn3)n2)c1 +Cc1ccc(-c2nnc(SCc3cccc(C(N)=O)c3)n2C)cc1 +COc1cc(F)c(S(=O)(=O)N(C)CCC(F)(F)F)cc1OC +CCNC(=O)c1cc(S(=O)(=O)Nc2cccc(C)c2)cs1 +CS(=O)(=O)N(Cc1ccon1)c1ccc2c(c1)OCO2 +O=C(Cc1ccccc1Cl)Nc1ccc2c(c1)NC(=O)CO2 +CC(NC(=O)c1csc(Cc2cccc(F)c2)n1)c1ncon1 +COCCN1CCCC2(CCN(C(=O)c3ccnc(OC)c3)C2)C1=O +O=C(Cc1nc(-c2ccccc2)cs1)NCc1ccccc1 +CCCn1cnc2cc(NC(=O)N3CCC(F)(F)CC3)ccc21 +O=C(c1n[nH]c2c1COc1ccccc1-2)N1CCCCCC1 +COc1ccc(Cl)cc1NCC(=O)N(Cc1cccnc1)C1CC1 +CN(C(=O)C1CC(=O)N(CCc2ccccc2)C1)c1nccs1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)C(C#N)c2ccccn2)c1 +O=C(Nc1ccc(Br)c(C(F)(F)F)c1)C1CCCO1 +Cn1c(=O)oc2cc(S(=O)(=O)NCc3cccs3)ccc21 +C=C(C)COc1cccc(C(=O)N2CCCC2C(N)=O)c1 +COC(=O)CSc1nc(C(C)C)nc2ccccc12 +CCC1c2ccsc2CCN1C(=O)Cn1ccc(C)cc1=O +Cc1cc(C(=O)Nc2ccc3c(c2)OCC(C)(C)C(=O)N3C)c(C)o1 +CS(=O)(=O)NCCCSc1nccn1-c1cccc(F)c1 +CC(=O)N1CCCC(c2ncc(C(=O)N3CCCC3)c(C)n2)C1 +CCN(CC)C(=O)c1ccc2c(c1)CC(=O)N2Cc1cccc(F)c1 +CCOC(=O)c1cc(CCc2ccccc2)nn1C +Cc1nc(C2(NC(=O)Nc3nc4ccccn4n3)CCCC2)no1 +CCc1noc(C)c1C(=O)N1CCN(Cc2ccccc2C)CC1 +COc1ccc2cc(C(=O)NCCNS(C)(=O)=O)[nH]c2c1 +Cc1cnc(N2CC3CCN(CC4CC4)C(=O)C3C2)nc1 +CC(=O)Nc1ccc(O)c(C(=O)Nc2ccc(C)c(C)c2)c1 +CCC1=NS(=O)(=O)c2cccnc2N1c1cc(OC)cc(OC)c1 +O=C(CC1CCCO1)NCC1(c2ccccc2)CC1 +N#CC(c1ccccc1)c1ccc(-c2ccccc2)nn1 +COCCN(CC(F)(F)F)C(=O)c1cccc(OC)c1F +CN(Cc1ccccn1)C(=O)Cn1cc(Br)ccc1=O +Cc1ccc(C(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)c(C)c1 +CC(C)(C)OC(=O)N1CCC2c3ccccc3CNC2C1 +CN(C(=O)c1cccc(Cl)c1F)c1ncccc1C#N +CN1C(=O)C2(CCN(C(=O)CC(C)(C)C)C2)c2ccccc21 +CCC(=O)N1CCC(n2c(CC3CCCC3)nc3cccnc32)CC1 +CCNC(=O)c1cccc(CNC(=O)NCc2cccs2)c1 +COc1ccc(C(=O)N2CCCC2C(=O)NC2CC2)cc1 +CCOC(=O)c1cn(Cc2ccccc2)c2nc(C)ccc2c1=O +COc1cccc(N2CCN(C(=O)c3ccoc3C)CC2)c1 +O=C(NCCNc1nc2ccccc2s1)NCC1CCOC1 +Cc1ccc(-n2ncc(C(=O)NC3CC3)c2C(C)C)cc1 +COc1ccc(-c2csc(CN3CCN(C(C)=O)CC3)n2)cc1 +Cc1nn(-c2ccccc2)c(C)c1CNc1ccc2nnnn2n1 +O=C(Cc1cccc(O)c1)Nc1ccnn1Cc1ccsc1 +CN(CCC#N)C(=O)Cc1c(F)cccc1Cl +CSc1ccc(OCc2nnnn2C2CC2)cc1 +COCCOc1ccccc1NC(=O)C1CCC(=O)N1 +CCOC(=O)Nc1ccc(NC(=O)Cc2ccc[nH]2)cc1 +N#CCc1ccc(NC(=O)c2cc(-c3ccccc3)[nH]n2)cc1 +COc1ccc(O)c(C(=O)Nc2ccc(C)cn2)c1 +COCCn1ncc2ccc(NC(=O)c3ccc4c(c3)COC4)cc21 +Cc1ccc(S(=O)(=O)N2CCC(Cn3cccn3)CC2)cc1 +CC(=O)N1c2ccc(Br)cc2C(=O)C1C +COC(=O)c1ccc(S(=O)(=O)N2CCNCC2)cc1 +Cc1ccccc1C(=O)NCc1cc(-c2ccco2)n(C)n1 +CC(CCO)NC(=O)Nc1ccc(C(F)(F)F)cc1 +C=CCN1C(=O)CCC2C1CCN2Cc1cccs1 +CCC(CO)NC(=O)c1nnc2n(c1=O)CCN2c1ccc(C)cc1 +Cc1ncc(CNC(=O)NCc2cnc(C)s2)s1 +CCc1nnc(NCc2cn3c(n2)SCC3)o1 +CC(=O)c1ccc(NC(=O)CCn2cc(C)cn2)cc1C +CC1CC1C(=O)Nc1cccc(C(=O)Nc2ccc(=O)n(C)c2)c1 +OCCSc1nc(C(F)(F)F)nc2ccccc12 +Cc1ccccc1OCCC(=O)Nc1cccc2cccnc12 +CCOC(=O)C=C(Nc1ccc2[nH]ncc2c1)C(F)(F)F +CCOC(=O)N1CCN(C(=O)c2ccc(=O)n(C)c2)CC1 +O=C(Cn1ncc(=O)c2ccccc21)OCCc1cccs1 +CC1(C)CN(CCC(=O)Nc2ccccc2Br)CCO1 +COc1ccc(C(=O)CCC(=O)N2CCOCC2)cc1F +N#CCCN1CCCN(c2ccccc2C#N)CC1 +CC(NC(=O)c1cccnc1N(C)C)c1ccccc1Br +CCCC(O)CNC(=O)Nc1cc(-c2ncco2)ccc1C +COc1ccc(C(=O)N(C)C(C)c2cccnc2)c(Br)c1 +N#Cc1ccc(-c2ccccn2)n(CCN2CCOCC2)c1=O +CC1CCCC(NC(=O)c2cc(N)ccc2Cl)C1C +Clc1ccc(NCC2Cc3ccccc3O2)nc1 +Cc1cn(-c2ccccc2)nc1NC(=O)N1CCOCC1C1CC1 +N#Cc1ccccc1N1CCN(Cc2cc3ccccc3[nH]c2=O)CC1 +CCOCC(=O)N1CC2CCN(c3ncccn3)CC2C1 +COc1nn(C)cc1C(=O)NCc1cc(-c2ccncc2)n(C)n1 +Cn1nc(C(=O)Nc2nccs2)cc1C(F)(F)F +CC(=O)NCCCS(=O)(=O)c1nccn1-c1ccc(C)cc1C +COC(CNC(=O)NCC(C)(C)c1ccncc1)C(C)(C)C +CC(C)(C)OC(=O)NCc1ccc(S(N)(=O)=O)cc1 +O=C(COc1ccccc1)N1CCN(CC2CC=CCC2)CC1 +CCc1onc(C)c1NC(=O)NC1CCc2c(O)cccc21 +CC(C)NC(=O)C(C#N)c1ccc(N2CCOCC2)nn1 +CCc1c(C(=O)N(CC)Cc2cnn(C)c2)cnn1-c1ccccc1 +Cc1ccc(OCC(=O)NC(C)c2c(C)noc2C)cc1 +CCCS(=O)(=O)c1ccc(Nc2cnn(C)c2)cc1 +COc1cccc(C(=O)Nc2ccc(N)cn2)c1O +Cc1ccc(NC(=O)CSc2nncn2C)cc1N +C=CCC(NC(=O)OC(C)(C)C)c1cccc(OC)c1 +Cn1cnnc1-c1ccc(NC(=O)CCc2ccc(F)c(F)c2)cc1 +O=C(NC1CCC(O)CC1)c1ccc(-c2nc3ccccc3s2)o1 +Cc1nnc2ccc(N3CCN(Cc4cnc5ncccn45)CC3)nn12 +COc1cc2c(c(OC)c1OC)C(c1nc[nH]n1)NCC2 +Cc1n[nH]c(C)c1NC(=O)COc1ccc2ccc(=O)oc2c1 +CCC(NC(=O)c1cn(CCOC)c2ccccc12)c1ccncc1 +O=C(CNc1ccccc1Cl)N(Cc1ccccn1)C1CC1 +O=C(Nc1ccc2[nH]ccc2c1)c1ccc(-n2ccnc2)cc1 +CNc1snc(C)c1C(=O)OCc1nc(C(C)C)no1 +Cc1nc(C)c(CCC(=O)Nc2ccc(-c3ccccc3)cc2)c(=O)[nH]1 +O=C(c1[nH]ncc1Br)N1CCOc2cc(F)ccc21 +c1ccc(-c2ccc(OCCCCn3cncn3)cc2)cc1 +O=C(CCc1ccco1)Nc1cnc(-c2ccccc2)nc1 +Cc1ccc(CCCNS(=O)(=O)N(C)C(C)C)c(C)c1 +CCN(Cc1ccc2c(c1)OCCO2)S(=O)(=O)N(C)C(C)C +CC(C)C(NC(N)=O)C(=O)Nc1cccc(C#Cc2ccccc2)c1 +O=C(Oc1ccc(F)cc1Cl)c1cc(C2CC2)[nH]n1 +N#Cc1cccc(Cn2nccc2-c2ccncc2)c1 +O=C(CCc1cc(F)ccc1F)OCC(=O)N1CCc2ccccc21 +COc1cc(OC)c(-c2cn[nH]c(=O)c2N)c(OC)c1 +Cc1cccc(OC2CCN(C(=O)c3ccn(C)n3)CC2)c1 +CCOC(=O)c1sc(NC(=O)C(C)OC)cc1C +COc1cccc(C(=O)OCc2ccccc2)c1F +N#Cc1ncn(Cc2c(-c3ccccc3)nc3ccccn23)n1 +Cc1cccc(C(N)C(=O)NCCCCCO)c1C +O=C(Nc1ccncc1)N1CCC(Cc2cccc(F)c2)CC1 +Cc1cccc2c(-c3ncccc3C(N)=O)c[nH]c12 +CCC(CC)N(CCOC)C(=O)c1cccc(F)c1F +Cc1csc(CNC(=O)NC(C)C(=O)N2CCCCC2C)n1 +COC(=O)C1(N(C)C(=O)CCCc2ccccn2)CCCCC1 +CNC(=O)c1ccc(CNC(=O)CCc2ccsc2)cc1 +O=C(c1nccs1)C1CCN(C(=O)C2(c3ccccc3)CC2)CC1 +Cc1occc1C(=O)Nc1cccc(-c2cn[nH]c2)c1 +Cc1ccc2ncc(C(=O)NCCCOC3CCOC3)n2c1 +COC(=O)c1cc(=O)c2cc(Br)ccc2o1 +CC(=O)Nc1cccc(NC(=O)Cn2nc3ccccn3c2=O)c1C +CC(=O)c1ccc(Oc2ccc(C(=O)NCc3cccnc3)cc2)cc1 +NC(=O)C1CN(Cc2ccccc2OCC2CC2)CCO1 +CC(C)(C)c1nnc(COc2nncc3ccccc23)o1 +Cc1c(C(=O)NCCCC(=O)NC(C)C)nc2cc(Cl)ccn12 +O=C1NCC(=O)N2CCN(C(=O)c3ccccc3)CC12 +COc1ccccc1C1(CNC(=O)c2cc(C(C)=O)c[nH]2)CC1 +Nc1cccc(-c2noc(-c3ccccc3F)n2)c1 +COc1ccc(-c2cc(C(=O)N(C)C)c3ccccc3n2)cc1OC +NC(=O)CCc1ccccc1-c1nc2ccccc2o1 +COc1cc(OC)cc(C(=O)c2ccc(OCC(N)=O)cc2)c1 +Cc1ccc(NC(=O)c2noc3c2COc2ccc(C)cc2-3)nc1 +COc1ccc(NC(=O)CCCNC(=O)c2ccc(F)cc2F)cc1 +N#Cc1ccccc1NC(=O)CCCn1nnc(-c2ccccc2)n1 +Cc1ccc2c(CSc3nnnn3C)cc(=O)oc2c1C +CN(CCc1ccccc1)C(=O)C1CN(Cc2ccccc2)CCO1 +CCN1CCOC(C(=O)Nc2ccc(-n3ccnc3)nc2)C1 +COC(=O)C1CCCN1Cc1csc(-c2ccsc2)n1 +CCCc1nnc(C2CCN(C(=O)COC)C2)o1 +CCC(=O)Nc1ccc(Cl)c(S(=O)(=O)N2CCCCC2)c1 +O=C(NCCc1cccnc1)NCCc1nc2ccccc2s1 +CCOc1ccc(NC(=O)C2CCCN2C(=O)c2ccco2)cc1 +CCn1nc(C)c(CNc2cnn(CC(F)(F)F)c2)c1C +O=C(NCCO)C1CCN(CC(F)(F)F)CC1 +O=C(CNC(=O)Nc1c(F)cccc1F)Nc1cccc(F)c1 +O=C(NCCCn1nc2ccccn2c1=O)Nc1ccc(F)cc1 +Cc1nn(Cc2ccccc2)c(C)c1NC(=O)c1ccncc1 +CC(C)Sc1nnc(-c2cccs2)n1CCC(N)=O +O=C(Nn1cnc2c(cnn2-c2ccccc2)c1=O)c1ccccc1F +COC1CCCCC1NC(=O)N(C)C(C)C1CC1 +Cc1cc(C)nc(SCC(=O)OCc2ccc(C#N)cc2)n1 +CC(C)N(CCn1cc(N)ccc1=O)CC(F)(F)F +CCCCNC(=O)C1CCCN(C(=O)Cc2ccc(F)c(F)c2)C1 +CC(C)CN1CC2=C(C1=O)C(c1cccs1)NC(=O)N2 +Cc1nc(C)c(CC(=O)NC(c2ccccc2)c2ccco2)c(=O)[nH]1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCCC2c2cc(C)on2)cc1 +CC(C)c1csc(NC(=O)c2cccc(CC#N)c2)n1 +COC(=O)C1=C(C)N=C(C)C(C(=O)OC)C1c1cccs1 +COc1ccc(CN2CC(C(=O)O)C2=O)cc1OC +c1ccc(-n2nnnc2CN2CCCSc3ccccc32)cc1 +O=C(Cc1ccsc1)Nc1ccc(S(=O)(=O)C(F)F)cc1 +CC(C)(C)C(O)CCNS(=O)(=O)Cc1ccc(Cl)cc1 +CCOCCNC(=O)c1cccc(Oc2cnccn2)c1 +Fc1ccc(CN2CCc3cncnc3C2)c2ncccc12 +O=C(NC1CC1)C1CCCN(C(=O)c2ccc[nH]c2=O)C1 +Cc1nc(C(=O)NCC(N)=O)nn1-c1ccc(Cl)cc1 +Cc1c(C(=O)Nc2ccc3c(c2)nc(C)n3C)cnn1-c1ccncc1 +CCC(C)OC(C)C(=O)Nc1ccc(Cl)cc1N +Cc1cccc(N(CCC(N)=O)Cc2cc(=O)n3ccccc3n2)c1 +NC(=O)Cc1ccccc1NC(=O)c1ccc(Cl)cc1 +CCOC(=O)c1cn(CC2CCCCC2)c2nc(C)ccc2c1=O +Cn1ncc2c(N3CCN(CCO)CC3)nc(C3CCCC3)nc21 +Nc1cccc(-c2nnc3[nH]c4ccc(N)cc4n23)c1 +CCCn1nc(C(=O)N2CCN(c3cnccn3)CC2)ccc1=O +CCN(CC)C(=O)c1cccc(NC(=O)NCCc2cscn2)c1 +O=C(NCCCN1CCOCC1)c1cc(-c2ccccc2F)no1 +Cc1nc2n(c1C)CCN(CC(O)COCc1ccccc1F)C2 +CCn1cc(NCc2ccccc2C(=O)OC)cn1 +Cc1cnc(C(=O)N2CCC3(CC2)CC(c2ccccc2)CO3)cn1 +CC(C)N(C)C(=O)CN(C)S(=O)(=O)c1ccccc1 +O=C(NCCNC(=O)C1CC1)c1ccc(=O)n(-c2ccccc2)n1 +CN(C)c1cccc(C(=O)N2Cc3nc(-c4ccccc4)sc3C2)c1 +CCOC(=O)C1CCN(C(=O)c2cc3c(F)cccc3n2C)CC1 +CC1CN(C(=O)c2ccc(-c3noc(C(F)(F)F)n3)cc2)CCO1 +O=C(CC1CCCCC1)Nc1ccc(N2CCCC2=O)cc1 +Cc1ccc(NC(=O)c2cccc(S(=O)(=O)NC(C)C)c2)c(C)c1 +Cc1cccc(Nc2nc(NCCO)nc(N3CCCC3)n2)c1 +O=C(CCSc1ccccc1)N1CCOc2ccc(F)cc21 +CCC(CC)C(=O)N1CCC(NC(=O)NCc2cscn2)CC1 +CC(=O)c1c[nH]c(C(=O)Nc2nnc(C)s2)c1 +COCCOc1c(Cl)cccc1NC(=O)c1sc(C)nc1C +CCOC(=O)c1csc(-n2nc(C)c3nc4ccccc4nc32)n1 +O=C(Nc1ccc2c(c1)OCO2)c1cnc2n[nH]nc2c1 +Cc1ccc(NC(=O)C2CC2)cc1S(=O)(=O)N1CCCCCC1 +N#Cc1c2c(c(-c3ccc(Cl)cc3)[nH]c1=O)CCC2 +Cc1ccc(N2CCC(C(=O)OCC(N)=O)C2=O)cc1C +CN1CCCN(c2cccc(Br)c2)S1(=O)=O +COc1ccc(Cl)cc1-c1ccc(CC#N)c(=O)n1C +COc1cc(C)sc1C(=O)N1CCC(C(N)=O)CC1 +O=C(COc1cccc(Cl)c1)Nc1ccc2c(c1)NC(=O)CO2 +Cc1ccccc1OC1CN(C(=O)CCC(=O)NC2CCCC2)C1 +CN(C(=O)CCC(=O)N(CCC#N)c1ccccc1)C1(C#N)CCC1 +COc1ccc(O)c2c1C(c1nccs1)NCC2 +CC1CCCC(CNC(=O)Cn2cnc3c(cnn3C)c2=O)C1 +COc1ccc(-c2nc(COC(=O)CC(C)C)no2)cc1 +CCc1cccc(N2CC(C(=O)NC(C)(C)C(N)=O)CC2=O)c1 +COc1cccc(NC(=O)Cn2ccc3ccc(OC)cc3c2=O)c1 +COC(=O)c1c(NCCc2cccs2)c2ccc(F)cc2[nH]c1=O +Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCCC(C)C +CC(Cc1ccco1)NC(=O)c1cnc2sccn2c1=O +CC(=O)NCC(=O)Nc1ccc(-n2nc(C)cc2C)nc1 +CC(C)c1noc(CCNC(=O)c2cn3ccccc3n2)n1 +CCN(CCC#N)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +COc1cccc(C(=O)N2CCC(N(C)c3cccnn3)CC2)c1F +CC(=O)Nc1ccc(C#CCNC(=O)CNC(=O)c2ccccc2)cc1 +Cc1nnc2n1CCN(C(=O)c1sccc1C1CC1)C2 +C=CCN(CC=C)S(=O)(=O)c1ccc(Br)c(OC)c1 +Cc1ccc(NC(=O)NCc2ncc[nH]2)c(-c2nc(C3CC3)no2)c1 +Cc1cc(Br)c(=O)n(CCCC#N)c1 +COC(=O)CSc1cncc(N2CCOCC2)n1 +CNC(=O)NCC(=O)NCc1ccc(OCC(C)C)cc1 +Cc1cncc(C2NCCc3ccc(C)c(C)c32)c1 +CCC(C)n1ncc2c(C(=O)NC(C)c3nncn3C)cc(C)nc21 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1ccoc1C +C=CCNC(=O)N1CCN(CC(=O)Nc2cc(C)on2)CC1 +COc1ccc(-n2cc(CNC(=O)N3CC(C)CC(C)C3)nn2)cc1 +CC(C)Oc1ccc(NC(=O)CN(C)S(C)(=O)=O)cc1 +OC(CNc1ccccc1F)COc1ccc2c(c1)CCC2 +C#CCOC(=O)c1ccc(-c2ccc(N)cc2Cl)o1 +O=C(NCc1ccco1)N1CCC2(CCCN(CC3CC3)C2=O)C1 +O=C(CCn1c(=O)oc2ccccc21)Nc1ccc(-n2ccnc2)nc1 +O=S(=O)(NCCOCC(F)(F)F)c1ccc(Cl)cc1 +Cc1csc(-c2ccc(-c3csnn3)cc2)n1 +CC(NC(=O)c1ccoc1)C(=O)N(C)c1ccc(F)c(F)c1 +CC(=O)Oc1ccccc1N(C(C)=O)S(=O)(=O)c1ccc(C)cc1 +NC(=O)Cn1c(=O)ccc2cccc(OCc3ccccc3)c21 +Nc1cc(N)nc(SCc2cc(-c3cccs3)on2)n1 +CS(=O)(=O)c1cc(S(=O)(=O)Nc2ccccc2)ccc1F +O=C(CCc1nc2ccccc2[nH]1)Nc1ccccc1F +Cc1ccc2c(c1C)C(c1ccc(F)cn1)NCC2 +Nc1cc(-c2nnn(Cc3ccccc3)n2)ccc1O +COC(=O)c1sc(NC(=O)c2ccc(Cl)c(Cl)c2)nc1C +O=C(CCSc1ccccc1)Nc1cccc(C(=O)NC2CC2)c1 +CCn1c(CNc2cccc(COC)c2)nc2ccccc21 +CSc1ccc(OC(C)C(=O)N2CC(C)OC(C)C2)cc1 +COc1ccc(-c2nc(N)nc(Nc3ccc(C)cc3)n2)cn1 +Cc1ccc(N2CCCN(Cc3cccs3)CC2)nn1 +O=C(c1c[nH]c2cccc(F)c12)N1CCCC1C1CCCC1 +CNC(=O)c1ccc(Cl)cc1NC(=O)Cc1ccc(F)cc1F +CCc1ncc2c(n1)CN(Cc1cc(OC)c(OC)cc1OC)CC2 +O=C(Nc1nc(-c2ccccc2)cs1)c1ccsc1 +O=C(NCc1ncc[nH]1)Nc1cc(Cl)ccc1Br +O=C(COc1ccc(F)cc1)Nc1cc(F)c(F)c(F)c1 +Cc1ncc(CN2CCOC(Cn3cncn3)C2)s1 +COC(=O)c1ccc(Cn2cc(C(F)(F)F)ccc2=O)o1 +CC1(C)Oc2ccc(NC(=O)NCc3ncc[nH]3)cc2O1 +CCCn1nc(Oc2nc(SC)nc(N(C)C)n2)ccc1=O +CCOC(=O)C(NC)c1ccc(F)c(C(N)=O)c1 +Cc1cc(C)c(C(=O)N2CC=C(c3c[nH]c4ccccc34)CC2)c(=O)[nH]1 +CCN1CCOCC12CCN(C(=O)c1cccc(F)c1)CC2 +O=C(c1cc2c(s1)CCCC2)N1CCCC(C(=O)N2CCCC2)C1 +CSc1cccc(CNC(=O)C2CC(=O)N(C3CC3)C2)c1 +COc1ccc(-c2cc(C(=O)OCc3nc(C)no3)sc2C)cc1 +Cc1cc(C(=O)OCC#Cc2ccccc2)c2c(C)nn(C)c2n1 +C#CCn1c(CNC(=O)c2ccc(F)cc2)nc2ccccc21 +CCc1nc(NCCCOC)c2oc3ccccc3c2n1 +O=S(=O)(c1ccccc1F)N1CCCn2ncnc21 +COc1cccc(-c2n[nH]c3c2C(c2cccs2)NC3=O)c1 +O=C(NCC1Cc2ccccc21)c1c[nH]c2cccc(F)c12 +O=C(Nc1ccc(N2CCCC2)nc1)c1cc(=O)[nH]c2ccccc12 +CC1CC(N2CCOCC2)c2cccc(C(C)C)c2N1 +CNC(=O)CSc1nnc(-c2ccoc2C)n1-c1ccccc1 +Cc1occc1C(=O)Nc1ccccc1-n1cncn1 +Cc1cc(C)cc(-c2csc(-c3nonc3N)n2)c1 +CC(C)N(C)C(=O)C1CC1c1ccc(Br)cc1 +Nc1cc(=O)n(Cc2ccccc2)c(N)c1C(=O)NCc1ccccc1 +CCOc1cc(CNC(=O)N2CCC(C)CC2)ccn1 +Cc1ncsc1CN(CCC#N)CC(C)(C)C +O=C(CC(F)(F)F)NC1CCc2c(Cl)cccc21 +O=S(=O)(NCc1nccs1)c1ccccc1OC(F)(F)F +Cc1nc2sccc2c(=O)n1NC(=O)c1ccccn1 +CS(=O)(=O)c1ccc(NC2CCCNC2=O)c(N)c1 +O=C(C1CCCO1)N1CCN(Cc2ccc(-n3cccn3)cc2)CC1 +O=C(CCc1ccccn1)NCC(O)c1cc2ccccc2s1 +O=c1oc(-c2ccccc2)nn1CC(O)c1c(F)cccc1F +CC(C)N(C(=O)Cn1cc(Cl)cn1)c1ccccc1 +Cc1cc(NC(=O)CCn2cnc3sc(C)cc3c2=O)no1 +O=C(Cc1ccc(F)cc1)Nn1cnc2ccccc2c1=O +C=CCN(Cc1ccccc1Cl)C(=O)COc1cccnc1 +CC(C)n1c(SCC(=O)NC2CC2)nnc1-c1ccco1 +Cc1ccc(CC(=O)N2CCC(Nc3cccnn3)CC2)s1 +CC1CCN(C(=O)c2ccc(-c3cncnc3)nc2)CC1 +Cc1ccc(C(CC(=O)OC(C)C)NC(=O)c2ccc(C)s2)cc1 +COC(=O)C(NC(=O)c1ccc(NC(=O)C2CC2C)cc1)C(C)C +CCN(Cc1ccccc1)C(=O)Cn1c(C)c(C)sc1=O +Cc1nc2ccc(NC(=O)CCc3nc(-c4ccncc4)no3)cc2o1 +Cc1ccc(NC(=O)Nc2cn(C)c(=O)c3ccccc23)cc1F +COc1cc(NC(=O)Nc2nnc(-c3ccn(C)n3)o2)cc(OC)c1 +CCC(C)Nc1nc(-c2ccncc2)nc2c1CCN(C(C)=O)C2 +Cc1oc(NC(=O)CN2CCOCC2C2CC2)c(C#N)c1C +CCN1CCN(Cc2nc(-c3ccc(Cl)cc3)oc2C)C(C)C1=O +Cc1ccc(C(=O)COC(=O)Cn2c(C)nc3ccccc32)cc1 +CC(NC(=O)c1cc(-c2ccccc2)on1)C(=O)N1CCOCC1 +Cc1ccsc1C(=O)NCCc1ccc(F)cc1 +c1cc(CN2CCCCC2c2ccncn2)ccn1 +CN(Cc1ccncc1)C(=O)Nc1ccn(Cc2ccccc2)n1 +Cc1ccc(-c2noc(C(=O)Nc3ccccc3)n2)cc1F +COc1ccc(C(C)=O)c(OC(C)C(=O)Nc2c(C)cccc2C)c1 +COC(=O)COc1ccc(CSc2nnc(C)s2)cc1 +Nc1ccsc1C(=O)NC1CCc2ccccc2C1 +CN(Cc1cncnc1)C1CN(Cc2ccsc2)C2CCCOC12 +COC(CNC(=O)C(C)(C)C)c1cccc(F)c1 +CCOc1cccc(C(=O)Nc2ccc(NC(C)=O)cc2)c1 +Cn1nnc2c(N3CC(C(=O)NCC(N)=O)C3)ncnc21 +O=C(Cc1ccc2ccccc2c1)NCCC(=O)N1CCCC1 +COC(=O)c1ccc(NC(=O)CSc2cn[nH]n2)cc1 +CC(=O)N(C)Cc1nc2ccccc2n1CCC(C)C +CCn1nc(C)cc1C(=O)Nc1cc2ccccc2oc1=O +CC(C)(C)C(=O)N1CCN(S(=O)(=O)N2CCCCCC2)CC1 +CCC(=O)N1CCN(C(=O)c2cc3n(n2)CCCO3)CC1 +CCOc1ccc(N2C(=O)c3ccccc3S2(=O)=O)cc1 +CCn1cc(C(=O)N2CCOC(c3ccccc3)C2)c(C(C)C)n1 +CC(=O)c1ccc(NC(=O)CCCC(=O)c2ccccc2)cc1 +CS(=O)c1ncc2c(n1)CN(C(=O)OC(C)(C)C)C2 +CCCC(=O)N(CC)CC(=O)Nc1ccc2c(c1)OCCO2 +CC(=O)Nc1cccc(C(=O)NCC2CCCO2)c1 +COc1ccccc1NC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 +Cc1ccc(S(=O)(=O)NC2CCc3c(F)cccc32)cc1 +COC(=O)CC1CCCCN1C(=O)CN1CCCC1=O +CN(CCOc1ccccc1F)C(=O)NCc1ncn(C)n1 +O=C(c1ccncc1F)N1CCC2C1CCN2c1nncs1 +CCOc1c(N)cc(Cl)cc1Br +COc1c(F)cc(NC(=O)c2ccc(F)c(NC(C)=O)c2)cc1F +NC(=O)C1CCN(C(=O)CCc2ccc3c(c2)OCO3)CC1 +NC(=O)C1CCCN(C(=O)Cn2c(=O)[nH]c3ccccc32)C1 +Cc1noc(C)c1CC(=O)Nc1cc(Br)c[nH]c1=O +NC(=O)C1CCN(C(=O)NCCc2c(Cl)cccc2Cl)CC1 +COc1nnc(C(=O)NCc2ccc(C)cc2)s1 +CN(C)C(CNS(=O)(=O)c1cccc(C#N)c1)c1cccs1 +Cc1cc(NC(=O)NC(C)c2ccc(Cl)cc2)no1 +CN(C)C(=O)CCNC(=O)NCc1ccc(C#N)cc1 +Cc1nc2ccc(NC(=O)N(C)Cc3ccccc3)cc2s1 +COC(C)C(=O)Oc1ccc(Br)cc1C(C)=O +CC(C)c1cc(CNC(=O)N2CCc3cc(F)ccc3C2)on1 +Cc1cc(CC(C)NC(=O)CCn2c(C)cc(C)nc2=O)[nH]n1 +Cc1ccccc1OCC(=O)Nc1cc(Cl)ccc1N +O=C(c1ccsc1)N(CC(F)(F)F)C1CCOCC1 +CC(Cc1ccc(O)cc1)NC(=O)c1nc2ccccc2c(=O)[nH]1 +Cc1ccc(NC(=O)N(C)CCOCC2CC2)c2[nH]ncc12 +COC(=O)N1CCc2ccc(NC(=O)c3ccccc3Cl)cc2C1 +CN(Cc1cscn1)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(NC(=O)COc1ccc(C(N)=O)cc1)c1ccccc1 +COc1ccc(NC(=O)Nc2ccc3[nH]c(=O)oc3c2)cc1 +N#Cc1ccsc1C(=O)Nc1ncccc1Cl +CC(O)(CNC(=O)CCC1CCCO1)c1ccc(F)cc1F +Cc1nn(C)c2[nH]c(=O)c(CCC(=O)NCC3CCCCC3)c(C)c12 +CN(Cc1ccc(C#N)cc1)C(=O)c1cnc(Cc2ccccc2)s1 +COc1cccc(C(=O)N(C)Cc2cc3ccccc3[nH]c2=O)c1 +COC(=O)CCC(=O)Nc1cccc(Oc2ccccc2)c1 +COc1cc(C)ccc1OCc1ccc(C#N)cc1F +NC(=O)N1CCC(NC(=O)c2cc3ccccc3cc2OC(F)F)C1 +NC(=O)CCn1nnc(-c2ccccc2Br)n1 +C=CCN1CCN(C(=O)c2c(-c3ccccc3Cl)noc2C)CC1 +NC(=O)C1CCN(C(=O)c2cccnc2SCC(F)(F)F)CC1 +COc1ccc(OC)c(C(C)NC(=O)CCn2ccc(C)n2)c1 +CC(C)(CNC(=O)CC1CCOc2ccccc21)c1ccncc1 +Cc1ccc(C(=O)NC(C)c2ccccc2)cc1S(N)(=O)=O +COc1ccc(C(C)=O)cc1CC(=O)NC1CCC(O)CC1 +Cc1n[nH]c(C)c1NC1CS(=O)(=O)c2ccccc21 +Nc1ccc(C(=O)NCC2CCCCO2)cc1F +Cc1n[nH]c(C)c1NC(=O)CN1CCCC(NS(C)(=O)=O)C1 +Cc1ccc(NCC(=O)Nc2ccccc2C(N)=O)cc1Cl +COC(=O)c1nnn(-c2cc(Cl)ccc2Cl)c1N +COCCNC(=O)C1CCCN(c2nc3cccnc3s2)C1 +N#CCCn1ccnc1C(=O)c1ccc(Cl)cc1 +Cc1cc(C(=O)N(C)Cc2ccc3c(c2)OCO3)no1 +CSc1cc2c(cc1NC(=O)NCC(=O)NC1CC1)OCCO2 +CC(C)C(C)NC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +C=C(C)CN1C(=O)C(O)(CC(=O)c2ccncc2)c2ccccc21 +CC(C)N(C(=O)c1cccc(N2CCOC2=O)c1)C1CCOCC1 +CSc1ccc(Cl)c(C(=O)NCc2ccco2)c1 +CCC(=O)NCCc1csc(-n2cccn2)n1 +COc1cc(OC)c(C(=O)NC2CC2)cc1OC +CC(=O)c1ccc(NC(=O)c2ccc(-c3noc(C)n3)cc2)cc1 +O=C(Nc1ccc(Cl)cc1)Nc1cccc(O)c1 +O=C(CN1CCN(c2cccc(Cl)c2)C1=O)NC1CCCC1 +Cc1cccc2c(=O)c(NC(=O)N3CCCCC3)c[nH]c12 +CNC(=O)c1ccc(OC)c(NCC(=O)Nc2cc(C)no2)c1 +CCC(CC)CC(=O)NC(C)Cc1c(C)nn(C)c1C +COCCCNC(=O)Nc1ccc2c(c1)oc(=O)n2C +O=C(NCCc1ccccn1)c1cc(F)cc(F)c1 +COc1ccc(-c2nc3ccc(F)cn3c2C(C)O)cc1 +CCN(CC1CCOC1)C(=O)COCc1nc2ccccc2s1 +CC(NC(=O)c1cccc(N2CCCC2=O)c1)c1ccc(F)c(F)c1 +N#CCC(O)CCOc1ccc(-c2ccccc2)cc1 +COCCNC(=O)C(C)Oc1ccc(OC)cc1 +CC(O)CCN(C)C(=O)Nc1ccc(CN2CCCC2=O)cc1 +Cc1ccc(CCC(=O)Nc2cccnc2N2CCOCC2)cc1 +Cc1nc(NC(=O)c2ccc(Br)cn2)sc1C +CN(Cc1ccc2c(c1)OCO2)C(=O)Cc1ccc(F)cc1F +CCN(C(=O)C1CCCN(c2ccc(=O)n(C)n2)C1)c1ccccc1 +O=C(Cn1cnc2cc3c(cc21)OCCO3)NCC1CCCO1 +CNC(=O)c1cc(-c2ccc(C)o2)nc2ccccc12 +NC(=O)c1cc(S(=O)(=O)N2CCCCC2)ccc1N1CCCC1 +CC(=O)c1ccc(C(=O)Nc2ccccc2C(N)=O)cc1 +COc1ccc(C(=O)CNC(=O)c2ccc(F)c(C)c2)cc1 +O=C(NCc1ccco1)C1CN(c2nc3c(F)cccc3s2)C1 +C1CCCN(c2nc3nonc3nc2NC2CCOC2)CC1 +CCc1cc(=O)[nH]c(SCC(=O)Nc2cc(OC)ccc2OC)n1 +CCNc1ccc(Cl)cc1NC(=O)c1ccc(-n2cnnc2)cc1 +Cc1cc(C(=O)N2CCC3OCCN(CC4CC4)C3CC2)no1 +CC1(C)CN(C(=O)C2CC2)CCN1C(=O)C1CCOCC1 +Cc1cc(CN(C)C(=O)NCCCC2CCCC2)no1 +CC(C)(C)OC(=O)N1CCNCC1Cc1c[nH]c2ccccc12 +COc1ccccc1-c1ccc(=O)n(CC(=O)NC(C)C)n1 +CCc1ccc(NC(=O)Cn2ncccc2=O)cc1 +CC(C)OCCSc1nnc(-c2ccco2)n1N +CCCCN(C)C(=O)C1CCN(C(=O)NCc2cccnc2)CC1 +O=C(CN1C(=O)CSc2ccccc21)Oc1ccc2[nH]ccc2c1 +COCCN(C)C(=O)CCc1c(C)nc2ncnn2c1C +CNS(=O)(=O)c1ccc2c(c1)OC(C)(C)C(=O)N2 +CCC(C)n1ncc(C(=O)Nc2ccc(C#N)cc2)c1C1CC1 +COC(=O)c1ccc(C)c(NC(=O)c2cnc3ccccn3c2=O)c1 +CC(O)CNC(=O)c1nn(C(C)C)c(=O)c2ccccc12 +c1cn(C2CCCC2)nc1CSc1nnnn1CC1CCCO1 +CN(Cc1cccc(C#N)c1)Cc1ccnc(N)c1 +CCOC(=O)c1ccc(NC(=O)N(CC)CC)cc1 +CC1CCCCN1C(=O)c1ccc(NC(=O)c2cnn(C)c2)cc1 +Cc1cc(C(=O)NCc2ccnc(OC3CCC3)c2)nn1C(C)(C)C +CCC1CCCCN1C(=O)C1CC(=O)N(c2ccccc2)C1 +COc1ccc(-n2cc(-c3cc(Cl)ccc3O)nn2)cc1N +Cc1noc(COC(=O)c2cccc(OCC3CCCO3)c2)n1 +Cc1cc(N)ccc1NC(=O)CCCSc1ncn[nH]1 +COc1ccccc1N1CCN(C(=O)CCC(C)C)CC1 +COc1nn(C)c2nc(C)c(CCC(=O)NCC3CCCO3)c(C)c12 +Cc1cc(C)nc(NC(=O)c2ccc(Cl)c(N)c2)n1 +O=C(NC1CC1)C1CCN(S(=O)(=O)c2ccccc2F)CC1 +O=C(Nc1ccc(Cl)cn1)C1CC1c1ccccc1 +COc1ccc2[nH]nc(C(=O)N3CC4CC=C(C)CC4C3)c2c1 +O=C(NCc1cnn2ccccc12)c1ccncc1 +Cc1c(CNC(=O)Nc2ccc(OCC(C)C)nc2)cnn1C +COc1ccc(-n2ccnc2-c2ccc(NC(C)=O)cc2)c(OC)n1 +O=C(NC1CCC(n2cnnc2)CC1)c1ccc2cccnc2n1 +N#Cc1ccc(NC(=O)C2CCN(C(=O)c3cccs3)CC2)cc1 +COCc1ccccc1NCC(=O)N1CCCC1c1cccs1 +CC(C)Oc1ccc(CCNc2ncnc3[nH]ncc23)cc1 +CN(CC1(c2ccccc2)CC1(C)C)C(=O)c1ccco1 +CC(C)c1nc(C2CCCO2)sc1C(C)(C)O +CCOc1cc(C2OCCCO2)cc(N)c1OCCC(C)C +O=C(NCc1ccccn1)c1sccc1C1CC1 +O=C(CS(=O)c1ccc(F)cc1)N1CCOCC1 +CCC1CCCCN1C(=O)C(C)Nc1cccc(NC(C)=O)c1C +O=C(c1cccc(OCC(F)F)n1)N1CCC(c2ccn[nH]2)CC1 +C1CN(c2nc(N3CCOCC3)nc(N3CCOCC3)n2)CCO1 +Cc1cnn(CCC(=O)N2CC(C(N)=O)CCC2C)c1 +Cn1ncc2c(NCC3(CO)CCC3)nc(C(C)(C)C)nc21 +Cc1nn(CCCC(=O)NCc2ccc(F)cc2)c(=O)c2nccn12 +CC(=O)N1CCC(NC(=O)c2c(C)noc2C(C)C)CC1 +Cc1noc(COC2CCN(C(=O)c3ccncc3)CC2)n1 +Cc1cccc(C(=O)N2CCCCC2C(N)=O)c1N +CS(=O)(=O)c1ccc(F)c(NCC(=O)NCc2cccs2)c1 +CCOCCCNC(=O)c1cn(C2CC2)c2cccc(N)c2c1=O +COC(=O)c1cc(C)c(C)c2c1NC(=O)CNC2=O +Cn1c(=O)ccn(CC(=O)NCCc2cccc(Cl)c2)c1=O +N#Cc1c(SCC(N)=O)nc(-c2cccs2)c2c1CCCC2 +CS(=O)(=O)N1CCCC(c2cnc(NC3CCCC3)cn2)C1 +C=CCN(Cc1ccc(SC)cc1)C(=O)C1CCOC1 +Cn1c(C(F)(F)F)nn(CCNC(=O)C(C)(C)C)c1=O +CC1CN(CC(=O)c2ccc3c(c2)OCO3)CCO1 +CCC(C)C(=O)N1CCCC(c2nc(-c3cccc(OC)c3)no2)C1 +COCCNC(=O)CSc1nc2ccccc2n(C)c1=O +CC1Cc2ccccc2N1C(=O)Cn1nnc(-c2cccs2)n1 +CCN1CC(COC(=O)c2c(C)noc2-c2ccccc2)CC1=O +Cc1ccc(C(N)=O)cc1NC(=O)N(C)CCN1CCOCC1 +CCn1ccc(NS(=O)(=O)c2ccc(C(C)C)cc2)n1 +C#CCN1CCN(C(=O)NCCc2cccc(OCC)c2)CC1 +COc1ccc(NC(C)=O)cc1NC(=O)CSc1ccccn1 +COc1ccc(CNC(=O)CNC(=O)c2nc(C(C)C)cs2)cc1 +COC(=O)C(Cc1c(C)cc(OC(C)=O)cc1C)NC(C)=O +Cc1cc(C(N)c2nc(C)c(C)s2)c2ccccc2n1 +CC(C)(C)NC(=O)c1ccccc1NC(=O)N1CCOCC1CCO +O=C(Cc1c[nH]c2ccccc12)N1CC(c2nc(-c3ccco3)no2)C1 +Cc1ccc(C2NC(=O)c3ccc(Cl)cc3N2)o1 +COCCCNC(=O)NCC1COc2ccccc2C1 +CNc1snc(C)c1C(=O)OCCOc1ccc(C#N)cc1 +O=C(CCNC(=O)c1ccco1)NC1(c2ccccc2)CCCCC1 +COc1ccc2c(CC(=O)OC(C)C(=O)NC3CC3)coc2c1 +N#Cc1cccc(CS(=O)(=O)NC2CCCn3ncnc32)c1 +Cc1nc(NCC(=O)c2cc3ccccc3o2)sc1C +FC(F)(F)c1cccc2c1CCNC2c1ccnnc1 +CC(C)(C)CC(=O)NC1CCCc2[nH]c(=O)ccc21 +NS(=O)(=O)c1cccc(C(=O)c2ccncc2)c1 +O=C(CCc1ccccc1)Nc1nnc(-c2ccncc2)o1 +CCc1nnc2n1CCN(C(=O)C1(c3cccc(C)c3)CCC1)C2 +CC(C)(C)CCNc1cc(C(N)=O)ccc1Cl +CCOC(=O)C(C)(C)C(C(C)C)N1CCOCC1 +CCNC(=O)COc1cccc(NC(=O)c2ccc3[nH]cnc3c2)c1 +CC1CN(C(=O)C(C)Sc2ccccc2)CC(C)O1 +CCN(Cc1cccc(F)c1)C(=O)COc1cccc2c1CCC2=O +Nc1cccnc1-n1nc(C(F)(F)F)cc1C(F)(F)F +O=C(NCc1ccnc(OC2CCC2)c1)Nc1nnc(C2CC2)s1 +O=C(Nc1ccccn1)C1(c2cccc(Cl)c2)CCOCC1 +CC(C)Cn1nccc1NC(=O)CSc1nc2ccccc2o1 +COc1ccc(CNC(=O)c2cccc(C(F)(F)F)c2)cc1OC +Cc1ccccc1C(=O)Nc1ccc(-c2cnco2)cc1 +CCc1cccc(C)c1NC(=O)CSc1ccccn1 +CCNC(=O)CSc1ccc(-c2ccccc2)nn1 +Cn1nc(C(=O)Oc2ccc(C#N)cc2)c2ccccc2c1=O +COc1ccccc1CCN(C)C(=O)NCc1ccc(C)nc1OC +O=C1CCc2cc(NC(=O)NC3C4CCC(C4)C3CO)ccc2N1 +CC1CCCC(C)N1C(=O)CN(C)S(=O)(=O)c1cccs1 +C#Cc1cccc(N(CC(=O)NC)C(=O)c2cccc(OC)c2F)c1 +CCc1cc(C(N)=O)c(NC(=O)c2ccccn2)s1 +Cc1nc(CN2CCN(C(=O)C(C)Sc3ccccn3)CC2)no1 +CC(=O)N1CC(C(=O)N(C)CC(=O)NC(C)(C)C)Oc2ccccc21 +CC1(C)COCCN1C(=O)CNS(=O)(=O)c1cccs1 +O=C(CC1CCC1)N1CCOC(c2cccc(OC(F)F)c2)C1 +CCn1c(=O)c2cc(C(=O)Nc3cnccc3C)nn2c2ccccc21 +CC(=O)c1c[nH]c(C(=O)NCc2csc(-c3ccccc3)n2)c1 +COc1ccc(OC)c(NCc2c(C)nn(-c3ccccc3)c2C)c1 +CCOc1c(Cl)cccc1NC(=O)c1nc2nccc(C)n2n1 +Cc1cc(C)n(C(=O)CSc2nc3ccccc3[nH]2)n1 +CN1CCn2c(nc3cc(NS(=O)(=O)c4ccccc4)ccc32)C1 +CC(C)(C)OC(=O)NCCC(=O)n1nnc2ccccc21 +COC(=O)c1nn(-c2ccc(C)cc2)c(C)c1Cl +COc1ccccc1C(NC(=O)c1n[nH]c(=O)[nH]1)C(C)(C)C +Cc1ccc(S(C)(=O)=O)cc1S(=O)(=O)Oc1ccccc1F +CC(C)Oc1ccc(CCNC(=O)CN2CCCC2=O)cc1 +COC(=O)Cc1cccc(NC(=O)c2cn(C)nc2C(C)(C)C)c1 +COc1ccc(NC(=O)c2cccc(C)c2)c(N)c1 +O=c1ccc2ccc(OCc3ccccn3)cc2o1 +Cc1ncc(C(=O)NCCc2ccccc2)c(C)c1N +O=C(CSc1nnc(NCc2ccccc2)s1)Nc1ccon1 +CC(C)c1nc(CC(=O)Nc2ccc(S(N)(=O)=O)cc2)cs1 +CCn1ccc2ccn(CC(=O)NCc3cccs3)c(=O)c21 +O=C1CC(C(=O)NCc2ccco2)C2(CCCC2)O1 +CCOCC(=O)Nc1ccc2nc(CN3CCOCC3)[nH]c2c1 +COc1ccc(CNC(=O)Nn2cnc3ccccc32)cc1 +Cc1nc(NCCO)c2c(C)c(C(=O)OC(C)C)sc2n1 +CC(OCc1ccccc1)C(=O)Nc1cccc(S(N)(=O)=O)c1 +NS(=O)(=O)c1ccc(NC(=O)c2cc(F)c(F)c(F)c2)cc1 +CC(=O)N1Cc2ccccc2CC1C(=O)NCc1ccccc1F +Cc1ccc(NC(=O)N2CCC(CO)CC2)cc1S(C)(=O)=O +Cc1oc2ncnc(NCc3cnn(C)c3C)c2c1C +COC(=O)c1ccc(C(=O)NCCc2ccccc2)cc1 +COCC(=O)NCCn1c(C)nc2ccccc2c1=O +O=c1ccc(C2NCCc3c2ccc(F)c3Cl)c[nH]1 +CC(=O)C(NC(=O)CN1CCCC2(C1)OCCO2)C(C)C +COc1ccc(C2CCN(C(=O)NCc3ncn(C)n3)C2)cc1 +O=C(COC(=O)c1cccnc1N1CCCC1)NC1CCCCC1 +COc1ccc(F)cc1COC(=O)c1n[nH]c2ccccc12 +COc1ccc(C(C)N(C)C(=O)c2ccsc2)cc1 +CC(C)c1noc(CCCNC(=O)c2ccc3[nH]cnc3c2)n1 +Cc1cnc2c(c1)nc(-c1ccccc1C)n2CCCC#N +Cc1cc(C)cc(C(=O)Nc2ccc(N)cc2Cl)c1 +COc1cc2c(cc1C(=O)Nc1ccccc1)OCCCO2 +Cc1ccc(-c2n[nH]cc2CN2CCN(C3CC3)C(=O)C2)cc1 +Cc1ccoc1C(=O)NCC1CCN(c2ccccc2)C1 +OC(c1ccccc1)C1NCCc2c1cc(F)c(F)c2F +COc1ccccc1C(=O)N1CCN(C(=O)C2CCCCC2)CC1 +O=C1CN(C(=O)c2ccc(Cl)cc2)c2ccccc2N1 +CCCn1nnnc1CN1CCN(c2ncnc3sccc23)CC1 +CNC(=O)c1cccc(S(=O)(=O)N(C)C2CCCCC2)c1 +Cc1n[nH]c(C(=O)N(C)Cc2cnn(C)c2)c1Br +O=S1(=O)CCCN1CCOc1ccccc1F +CCN(CC)c1ncnc2c1cnn2CC(=O)NCc1cccnc1 +Cc1cc(C(=O)N2CC(C(=O)Nc3cccc(Cl)c3C)C2)no1 +CN(CC(=O)Nc1cccc(C#N)c1)C(=O)c1ccccc1 +O=C(CNC(=O)Nc1ccc(F)cc1F)NCc1ccco1 +CCn1nc(C)cc1NS(=O)(=O)c1ccccc1 +Nc1nccnc1C(=O)NCC1CCN(c2ccccc2)C1 +Cc1cccc(-n2ccnc2SCCn2cccn2)c1 +COc1ccccc1C(=O)Nc1c(C)nn(C)c1C#N +CSc1n[nH]c2ncnc(NCc3ccc(C)cc3)c12 +Cc1nn(CC(=O)N2CCN(c3cnccn3)CC2)c(C)c1Cl +Cn1cc(-c2nnnn2-c2ccccc2)c(=O)c2ccccc21 +COc1cccc(CC(=O)NCC(=O)Nc2c(C)cc(C)cc2C)c1 +C=CCNC(=O)Cc1csc(Nc2cc(C)ccn2)n1 +Nc1ccc2c(c1)CCCN2S(=O)(=O)c1cn[nH]c1 +CCOc1cc(C#N)ccc1OCc1nnc(C)o1 +Fc1cccc(OCc2nnc3n2CCCCC3)c1 +CCN(CC)c1c(N)cc(C(=O)OC)cc1Cl +CCOC(C)C(=O)NCC1CCCc2cc(OC)ccc21 +Cc1c(CNC(=O)c2cccc(-n3cnnc3)c2)oc2ccccc12 +COc1ccccc1OCC(=O)Nc1cccc(C)n1 +O=C(NCc1ccc(OC(F)F)cc1)c1ccsc1 +CN(CC1CCCO1)C(=O)c1c[nH]nc1-c1ccccc1Cl +COCCNC(=O)CNS(=O)(=O)c1ccc(Cl)cc1 +CN(C)C(=O)c1cncc(N2CCC3(CCOCC3)CC2)n1 +CC(C)Cc1ccc(CN2CCN(CCn3cncn3)CC2)s1 +COc1cc(NC(C)=O)ccc1NC1CCN(CC(F)F)CC1 +CCNC(=O)C(C)NC(=O)c1cc(N)cnc1C +Brc1cccnc1OCC1CCOCC1 +CCSc1nnc(-c2ccco2)n1-c1ccccc1 +Cc1c(F)cccc1NC(=O)C1CC(O)CN1C(=O)OC(C)(C)C +CSc1cccc(NCc2ccc(F)cc2N)c1 +CN(C)C(=O)CCOc1c(Cl)cc(Cl)cc1CO +Cc1nc(CN2CCN(c3cnc4ccccc4n3)CC2)oc1C +Cc1cc(C)n2nc(CNC(=O)c3c(F)cccc3F)nc2n1 +COc1cc(OC)c(OC)c2c1CCNC2C(O)CO +CCn1c(CC2CCN(C(=O)C(C)n3cnnn3)CC2)n[nH]c1=O +COCc1nc2nc(C)nn2c(N)c1-c1ccc(OC)c(OC)c1 +CCOC(=O)c1c(C)[nH]c2cc(Br)c(OC)cc12 +CNc1snc(C)c1C(=O)NCc1cccc2ccccc12 +Cc1nnnn1-c1cccc(NCC(=O)N(C)C2CCCCC2)c1 +O=C(Nc1cccc(NC(=O)c2cc(Cl)c[nH]2)c1)c1ccncc1 +COCCN(C)C(=O)c1ccc(F)c(NC(C)=O)c1 +CCOc1ccccc1NC(=O)c1ccc(C#N)cc1 +CCc1ccc(C(NC(=O)Nc2cnn(C)c2)C(C)(C)C)o1 +CC(=O)Nc1nc2c(s1)CN(C(=O)c1cccc(C)c1)CC2 +COc1cc(-c2noc(Cn3cnnn3)n2)ccn1 +N#CC1(C(=O)Nc2cc(Br)ccc2F)CCCC1 +Cc1nc(Cc2noc(CCn3c(C)csc3=O)n2)no1 +COc1ccc(NC(C)=O)cc1S(=O)(=O)NCc1ccccc1C +COCC(NC(=O)Cc1c[nH]c2cc(F)ccc12)C(N)=O +Cc1c(NC(=O)CCC(C)(C)C)cccc1C(=O)N1CCCC1 +COc1ccc(NC(=O)c2ccc3c(c2)OCO3)c(Cl)c1 +O=C(OCc1ccccc1F)C1COc2ccccc2O1 +N#Cc1cccc(NC(=O)Cn2nc3ccccn3c2=O)c1 +CN(Cc1cnn(C)c1)C(=O)Nc1ccccc1-c1ccccc1 +O=C(Nc1ccc(Cl)c(Cl)c1)C1CC2CCC1O2 +COCCOc1ncccc1C(=O)N(C)C(C)c1cccnc1 +Cn1c(SCCOc2ccc3ccccc3c2)n[nH]c1=O +CCN(Cc1cccnc1C)C(C)c1ccc(F)cc1 +CCCS(=O)(=O)N1CC2CC(C(=O)N(C)C)C(C1)O2 +Cc1cc(C)c(C#N)c(SCC(=O)NCC(F)(F)F)n1 +COc1cc(-c2ccc3nc(C)[nH]c(=O)c3c2)nc(N)n1 +Cc1nnc2ccc(NCCC3=CCCCC3)nn12 +CSc1nnc(-c2ccccc2O)n1-c1ccccc1 +N#CC(OC(=O)Cc1ccc(F)c(F)c1)C1CC1 +CC(C)OCCC(=O)NCC(O)c1ccccc1Cl +CC(C)Cc1nc(CCc2cnn(C)c2)n(-c2ccc(F)cc2)n1 +CC(C)(C(=O)NCCCn1cncn1)c1cccc(C(F)(F)F)c1 +Cc1cc(C)n2ncc(C(=O)NCc3ccc4c(c3)OCO4)c2n1 +CCOCCNC(=O)c1cc(S(N)(=O)=O)c(C)cc1C +CCCOc1ccc(OCn2nc(N)cc2C)cc1 +Cc1ccc2c(c1)C(NC(=O)Cc1ccc(O)cc1)CNC2 +Cc1cnn(CCCCCSc2nnc3cc(C)nc(C)n23)c1 +O=C(CCn1ncc2ccccc21)NCc1ccc(Cl)cc1 +CC(Oc1ccccc1)C(=O)Nc1ccc(CN2CCOC2=O)cc1 +Cc1ccc(CC(=O)Nc2ccc(S(C)(=O)=O)cc2)cn1 +Cc1nn(C)c2ncc(NC(=O)c3c(Cl)cccc3Cl)cc12 +N#Cc1ccc(C(=O)Nc2cc(Cl)ccc2N)cc1 +Cc1nc2ccc(NC(=O)c3cn(CC(=O)N(C)C)nn3)cc2s1 +CCOC(=O)c1cc(C(=O)n2cc(Cl)cn2)nn1C +Cc1cc(NC(=O)C2CCN(CC(F)(F)F)CC2)no1 +Cc1cc(C(=O)CN2CCC(=O)CC2)c(C)n1C(C)C +CCOCC(=O)NC(C)(C)C(=O)Nc1ccccc1 +Cc1cc(CCNS(=O)(=O)c2cc(C)c(Cl)cc2Cl)on1 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccccc1 +CCC(C)c1noc(C2CCCN(C(=O)c3ccco3)C2)n1 +CC1CCCN(C(=O)NCC(C)(C)C(N)=O)CC1 +CC(CNC(=O)C(C)N1CCn2c(nn(C)c2=O)C1)c1ccccc1 +CC(C)NC(=O)c1sc2cnccc2c1-n1cccc1 +N#CCC(=O)COc1ccc(-c2ccccc2)cc1 +Cc1cc(-c2ccccc2)nn1-c1nc2c(c(=O)[nH]c(=O)n2C)n1C +CCc1ccc(NC(=O)NC2CCCc3occc32)cc1 +COCC(C)Nc1ncnc(Oc2ccc(C)cc2)c1N +CC(C(=O)Nc1nccs1)N1CCn2c(nnc2C2CC2)C1 +O=C(Cc1ccc2c(c1)OCC2)Nc1cccc(-c2nc[nH]n2)c1 +CCCCNC(=O)N1CCCC1C(=O)NCc1ccco1 +NC(=O)c1ccc(CNc2cccc(C(F)(F)F)c2)cc1 +O=c1cc[nH]cc1NCc1cc(F)c(F)cc1F +CCCOc1ccc(NC(=O)N(C)Cc2ccncc2)cc1Cl +COc1cc2c(cc1OC)CN(C(=O)c1ccc(C)cc1O)CC2 +CC(C)NC(=O)COC(=O)C1CC1c1ccc(C(F)(F)F)cc1 +CC(=O)c1c(C(C)=O)c(C)n(-c2ccc(Cl)c(N)c2)c1C +CCc1nc(NCCOC)c2cc(C)sc2n1 +Cc1nc(CNc2c(C)nn(C(C)C)c2C)cs1 +CC(C)NC(=O)c1ccc(=O)n(Cc2ccccc2)n1 +Cc1nn(C)c(C)c1CCC(=O)N1CCCC1c1ccc(Cl)cc1 +O=C(CCCNC(=O)c1ccccc1)Nc1nc2ccccc2s1 +CCCN1C(=O)COc2ccc(-c3noc(C4CCC4)n3)cc21 +CC1CCCCC1NC(=O)NCC(=O)N1CCCCC1 +NC(=O)C1CN(C(=O)NCCc2cccs2)CCO1 +CNC(=O)c1cccc(-c2cc(C)c(OC)c(C)c2)n1 +Cc1cc(Br)ccc1-n1ccnc1SCCO +CC(C)N(CC(N)=O)C(=O)C1CC1c1ccccc1Cl +NC(=O)c1cccnc1SCc1csc(-c2cccs2)n1 +CCOc1ccc(-n2ccc3c(cnc4nc(C)nn43)c2=O)cc1 +CC(=O)N1CCN(C(=O)CSc2cccc(C(F)(F)F)c2)CC1 +Cc1cccc(NCc2c(C)nc3sc(C)cn23)c1 +CCc1ccc(S(=O)(=O)N2CCCCC2CCO)s1 +CCCCCOC(=O)Nc1ccn(C2OC(C)C(O)C2O)c(=O)n1 +CCCC(NC(N)=O)C(=O)NCCc1cc(C)cc(C)c1 +Cc1ncc(CN2CCNC(=O)CC2c2ccccc2)s1 +CCCNC(=O)CCc1nnc(-c2ccoc2C)o1 +CC(NC(=O)N1CCCC1)c1cc(F)ccc1N1CCC(O)CC1 +CCc1nccn1Cc1cccc(Br)c1 +O=C1CC2(CCN(C(=O)c3ccsc3)CC2)c2ccccc2N1 +CCOC1CCN(C(=O)c2cc(C)n(-c3cccnc3)c2C)CC1 +Cc1cccc(OCc2ccc(C(=O)N3CCOCC3)cc2)c1 +Cc1cccc(CNS(=O)(=O)Cc2ccccc2C)c1 +CCCNC(=O)NC1CCN(c2c(F)cccc2F)C1=O +CN(CCOc1ccccc1)C(=O)Nc1cccnc1 +CCn1c(SC(C)C#N)nc2sc(C)c(C)c2c1=O +CC(=O)c1ccc(N2CCOC(C)(C)C2)c(Br)c1 +CC(=O)N(C)c1ccccc1NC(=O)C1COc2ccc(F)cc2C1 +CC(NC(=O)c1cccc(S(C)(=O)=O)c1)c1ccc(F)cc1F +COc1ccc(C(O)CCC(=O)NCc2cccnc2)cc1 +O=C(Nc1ccccc1F)c1c[nH]c2cc(Cl)ccc2c1=O +COc1ccc2c(C)c(C(=O)NC(C)Cc3cnccn3)oc2c1 +CCN(CC)C(=O)Nc1ccc(-n2cncn2)c(F)c1 +CCN(CC)C(=O)C(c1ccccc1)N1CCCC1 +Cc1cccc(-c2noc(CNC3(CO)Cc4ccccc4C3)n2)c1 +COC(=O)CCN(C)S(=O)(=O)c1cc(N)ccc1C +CCSc1cc(C(=O)Nc2ccccc2Cl)ccn1 +Cn1nc(C(=O)Nc2ccccc2NC(=O)c2cccnc2)ccc1=O +COCc1oc(-c2ccc(S(C)(=O)=O)cc2)cc1C#N +COc1cc(C)sc1C(=O)NCC1(c2ccccc2)CC1 +Cc1ccc(CCc2c(CO)nnn2-c2nccs2)cc1 +Cc1ccc(C)c2c(C)c(C(=O)NCCS(N)(=O)=O)oc12 +O=C(CNC(=O)c1cc2ccccc2[nH]1)NC(C1CC1)C1CC1 +COc1ccc(CCc2cc(OC)cc(=O)o2)cc1 +CCNc1nnc(SC(C)C(=O)NC(C)(C)C)s1 +CCc1nc(C2CCCN2C(=O)Cc2cn3ccccc3n2)no1 +c1csc(-c2nc(CN3CCOC(Cn4cccn4)C3)cs2)c1 +Cc1ccc2sc(N3CCN(C(=O)C4CC4)CC3)nc2c1C +CN(C)C(=O)c1ccc(NCc2cccn2C)cc1 +O=C(CSc1ccccc1C(=O)Nc1ccccc1)NC1CC1 +Cc1ccoc1C(=O)Nc1ccc(Cl)cc1N +CN(Cc1ccc(F)c(F)c1)C(=O)Nc1ccc(F)c(C#N)c1 +COc1nc(CC(C)C)nc(NCc2ccccc2F)c1N +Cc1nc(CN2CCOC3C(CNc4cccnc4)CCC32)cs1 +CCNC(=O)CN1CCN(c2cccc(C)c2C)CC1 +CC1CN(C(=O)Cc2c[nH]c3ccccc23)CCO1 +Cc1nc(SCC(=O)N(C)c2ccccc2)c2ccccc2n1 +CCCC(=O)NC(C)c1nc2cc(-c3ccc(OC)cc3)ncn2n1 +Cc1noc(C)c1COc1ccccc1C(=O)Nc1nccs1 +NC(=O)c1csc(C(=O)OC2CCCCCC2)c1 +Cc1ccccc1OC(=O)C1CCN(c2cc(F)cc(F)c2)C1=O +COC(=O)c1[nH]c(C(=O)OC)c(Cl)c(=O)c1Cl +CCN(CCCNC(=O)c1cn[nH]c1)S(C)(=O)=O +Cc1cc(C)cc(NC(=O)CCCS(=O)(=O)c2ccc(F)cc2)c1 +Cc1cc(NC(=O)c2ccccc2C(F)(F)F)on1 +COc1ccc(C(=O)NCc2cccnc2-n2ccnc2)c(O)c1 +CC(Cn1cncn1)NC(=O)N(C)Cc1cc(F)c(F)c(F)c1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)N1CCCC1c1ccccc1 +NCCN1CCc2ccc(S(=O)(=O)N3CCCC3)cc2C1 +Cc1nnc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)s1 +CNC(=O)C1CCN(Cc2nn3c(=O)cc(C)nc3s2)CC1 +COc1ccc(OC)c(S(=O)(=O)NC(C)Cc2ccccc2)c1 +COC1COC2C(NS(=O)(=O)c3ccccc3C#N)COC12 +CCOc1ccccc1OCCCC(=O)N1CCCCCC1 +Cc1cccc(CCCNc2ccc(C(N)=O)cc2)c1 +COC(=O)c1sccc1CSc1nc(N)cc(N)n1 +COc1ccc(CCNC(=O)NC(C)c2c(C)noc2C)cc1 +CCC(CC)C(=O)Nc1ccc(NC(=O)c2ccco2)cc1O +CCn1cc(NCc2ccc(Br)cc2F)cn1 +COc1ccc2[nH]c(C(=O)Nc3ccc(OC)nc3)cc2c1 +Cc1nc(C(C)NC(=O)CCC2CCCC2)n[nH]1 +CCCCOc1ccc(Cl)cc1CNC(=O)CC#N +CCn1ncc(Cl)c1C(=O)Nc1ccc(Cl)cc1 +CC(OC(=O)c1ccc(CO)cc1)C(=O)Nc1ccc(C#N)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)N1CCCCC1C(N)=O +O=C(Cc1ccccc1)N1CC(=O)N2CCc3ccccc3C2C1 +N#CCCC(=O)Nc1ccccc1Br +CNC(=O)c1cc(C)ccc1NC(=O)Cc1ccc(-n2cccn2)cc1 +O=C(NCC1CCCO1)c1ccc(-c2ccccc2Cl)o1 +O=C(NCc1nnc2ccccn12)c1cc(-c2cccc(F)c2)no1 +OCCn1c(-c2cccnc2)nc2cc(Cl)c(Cl)cc21 +Cc1cc(S(=O)(=O)N2CCCCC2CCO)c(C)s1 +COC(=O)c1cccc(C)c1S(=O)(=O)N(C)C +O=C(NCC1CCOC1)Nc1cccc(C(F)(F)F)c1 +CCCCN(CCO)C(=O)c1nc(C)n(-c2ccc(Cl)cc2)n1 +COc1cc(N2CCC3C2CCN3S(=O)(=O)C2CC2)ncn1 +COc1c2c(c(OC)c3occc13)OC(O)(C(F)(F)F)CC2=O +CCOc1ccc(-n2ccn(Cc3cccc(F)c3)c(=O)c2=O)cc1 +O=C(NCC#Cc1ccccc1)c1cc(F)cc(F)c1 +COCCn1cc(NC(=O)c2scnc2C2CC2)cn1 +CC(C)CNC(=O)c1cccc(NC(=O)C(C)C)c1 +COc1ccc(C2=CCN(C(=O)CCn3cncn3)CC2)cc1 +Cc1noc(C2CC3CCN(C(=O)c4ccoc4)CC3O2)n1 +CN(CCCOc1ccccc1)c1cccc(CO)c1 +O=C(NCc1cccs1)NCC1(O)CCc2ccccc21 +COc1ncccc1CNC(=O)NC1CC(=O)N(c2ccccc2)C1 +CCC(C)N(C)C(=O)c1ccc2c(c1)S(=O)(=O)N(CC)C2=O +CC(OCCC1CCCCN1C(=O)OC(C)(C)C)c1cnccn1 +COCCn1ccc2c(NC(=O)C(C)C)cccc21 +CCn1ncc(Br)c1-c1nn2c(C)nnc2s1 +CCOC(=O)C1CCCCN1C(=O)CN(C)CCC#N +CC1(C)CCN(C(=O)Nc2cnn(-c3ccccc3F)c2)C1 +CCc1nc2ccccc2n1C(CC)C(=O)NCc1cnn(CC)c1 +CC(=O)Nc1cccc(-n2nnc(CO)c2C2CCC2)c1 +O=C(NCC(=O)N1CCN(CCO)CC1)c1ccsc1 +CCN1C(=O)C(C)(C(=O)Nc2ncccc2C)Oc2ccccc21 +CCCc1c(C)nc2ncnn2c1SCC#CCO +COC(=O)C(C)NC(=O)COc1ccc(Cl)cc1Cl +Cc1cnn(CCC(=O)N(C)c2ccc(Br)cc2C)c1 +O=C(NCCN1CCOCC1)c1ccc(Cl)c(Cl)c1 +NC(=O)COC(=O)c1cccc(S(=O)(=O)N2CCCCC2)c1 +Cc1ccc(CNC(=O)c2nc(N)ccc2Cl)o1 +CC(C)(C(=O)OCCN1CCCC1=O)c1ccc(Cl)cc1 +Cc1cc(NC(=O)c2ccc(Br)cc2C)ccn1 +CCn1c(NC(=O)c2ccc3c(c2)OCC(=O)N3)nc2ccccc21 +CC(=O)Nc1cccc(C2NCCc3c2ccc(C)c3F)c1 +O=C(Nc1cccc(F)c1)N1CCC2(C1)C(=O)Nc1ccccc12 +CS(=O)(=O)N(CCCC(N)=O)c1cccc(C(F)(F)F)c1 +COC(=O)c1cc(NC(=O)c2occc2C)c(F)cc1F +CC(C)CN(C(=O)c1ccc2c(c1)CCN2S(C)(=O)=O)C1CC1 +Cc1ccccc1NC(=O)Cn1c(=O)oc2cccc(N)c21 +CCn1nnc2cc(C(=O)Nc3sc4c(c3C#N)CCC4)ccc21 +O=C(Nc1ccc(F)c(F)c1)c1cn(-c2cccc(Cl)c2)nn1 +Cc1ccc2nc(C)c(C)c(C(=O)NCC(O)c3cccs3)c2c1 +CCOc1cccc(CO)c1OCc1ccccc1 +C#CCNC(=O)CNC(=O)c1ccc(F)c(Br)c1 +COc1cccc(CNc2nc(C(F)(F)F)cc(=O)[nH]2)c1OC +CC1CN(CCNC(=O)Nc2ccncc2)CC(C)O1 +CC1CCc2c(sc3nnc(-c4cccc(N)c4)n23)C1 +O=C(Cn1nc(-c2ccccc2)ccc1=O)Nc1cccc(Cl)c1 +COc1ccc(CNC(=O)c2cc(C(C)(C)C)nn2C)cc1F +CCOC(=O)C1CCCN(C(=O)Cn2nnc(-c3ccccc3)n2)C1 +O=C(NCCc1cccc(F)c1)Nn1cnc2ccccc21 +CCOc1ccc(-c2ncc(C(=O)NC)c(N)n2)cc1 +CCOC(C)c1nc(Cc2nc(-c3ccc(C#N)cn3)no2)cs1 +Cn1cnc(CNC(=O)NC(c2ccccc2)C2CCCCC2)n1 +O=C(CCCc1ccc(Cl)cc1)NCCc1ccncc1 +CCOC(=O)NCCC(=O)N1CCN(c2ccc(Cl)cc2)CC1 +COc1ccccc1CNc1nc2ccccc2c(=O)n1CCCO +Cn1ccnc1SCc1ncc(-c2ccc(F)cc2)o1 +CC(C)CNC(=O)CNC(=O)CC1CCCCC1 +CN1CCN(C(=O)C2CN(S(=O)(=O)C3CC3)C2)CC1 +O=C(Cn1ncc(=O)c2ccccc21)Nc1ccc(F)cc1F +NC(=O)c1cc(Cl)cn(Cc2cccc(C(F)(F)F)c2)c1=O +COc1ccc(OC(C)c2nc(-c3cccnc3)no2)cc1 +Nc1cc(F)ccc1C1NCCc2cccc(F)c21 +Cc1csc(CNc2cnn(Cc3ccccc3)c2)n1 +C=CCN(Cc1cccnc1)C(=O)c1cc2n(n1)CCN(C(C)=O)C2 +Cc1noc(C)c1C(C)NC(=O)c1cncn1-c1ccccc1 +O=C(Cc1c[nH]c2ccccc12)N1CCOC(c2ccccc2)C1 +CCOC(=O)c1nc(NC)sc1C(=O)OCC +CCOC(=O)c1ccn(-c2ccc(NC(=O)N(CC)CC)cc2)n1 +CN(C)S(=O)(=O)CCNC(=O)c1cc(C2CC2)n[nH]1 +Cc1cccc(C(=O)OCC(=O)N2c3ccccc3CC2C)n1 +Cc1ccc(OCC(=O)N2CCCN(Cc3nccn3C)CC2)cc1 +Cc1nc2ccc(C(=O)N3CCCCC3)cc2s1 +CCc1c(C2CCN(C(=O)Nc3cccc(OC)c3)CC2)noc1N +COc1ccc2nc(C)c(C(=O)NC(C)c3ccccc3)cc2c1 +Cc1noc(C)c1NC(=O)Cc1cccc(C(F)(F)F)c1 +COC(=O)CNC(=O)CSc1cccc2cccc(Cl)c12 +CC(C)c1n[nH]c(NC(=O)c2ccc(-c3cscn3)cc2)n1 +CC(=O)Nc1cccc(-n2cnnc2SCc2ccccc2)c1 +OC(CNc1ccccc1C(F)(F)F)c1cccs1 +CC1(C(=O)NCc2cn3ccccc3n2)CC1(Cl)Cl +O=C(Cn1nnc2ccccc21)NC1CC1c1ccccc1 +CC(C)C(C)n1c(CCc2ccccc2)n[nH]c1=O +CCN(CCC#N)C(=O)Nc1cc(-c2ncco2)ccc1C +CS(=O)(=O)NC1CCCN(S(C)(=O)=O)C1 +COc1ccc2ccc(OCC(=O)N3CCOCC3)cc2c1 +Cc1cc2nc(COc3ccc(Cl)cc3)cc(=O)n2o1 +CC1CCc2c(C(=O)N3CCC(S(N)(=O)=O)CC3)csc2C1 +CCC1CCCCN1C(=O)CNS(=O)(=O)c1cn(C)cn1 +Cc1cccc(NC(=O)CNC(=O)c2cccc(F)c2)c1C +Cn1cc2c(n1)C(COc1cccnc1)CN(S(C)(=O)=O)C2 +Oc1ccccc1SCc1cnn(-c2ccccc2)c1 +Cc1ccc(CNC(=O)COC(=O)c2ccncc2)cc1 +CCc1cc2c(NCc3cccs3)ncnc2s1 +CCOC(=O)C1CCN(c2cccn3nc(N)nc23)CC1 +COC(=O)c1[nH]c(C)c(C(=O)COc2ccccc2OC)c1C +Cc1ccc(F)cc1NS(=O)(=O)c1cccc(N)c1 +COC(=O)N(C)c1ccc(NC(=O)Nc2ccc(F)cc2F)cc1 +Cc1noc(C)c1CNC(=O)C1CC(=O)N(C2CCCC2)C1 +CC(=O)C1(c2ccccc2)CCN(C(=O)C2CC3C=CC2C3)CC1 +O=C(OCC1CCCO1)c1cnc(C2CCCO2)s1 +Cc1noc(CN2CCN(S(=O)(=O)N(C)C)CC2)n1 +Cc1cccc(C)c1NC(=O)CNc1ccc(-n2cncn2)cc1 +COCCCNC(=O)c1snc(-c2ccccc2C)c1N +N#Cc1cccnc1NCC(O)c1ccc(F)c(F)c1 +CC(NC(=O)CCN1CCCCC1=O)c1ccc2[nH]ccc2c1 +COCC(C)NC(=O)N(C)CCOc1ccc(Cl)cc1 +CCOC(=O)N1CCC(NC(=O)c2cc3ccccc3oc2=O)CC1 +CC(O)c1cc(F)ccc1N(CCCO)C(C)C +COC(=O)NCCC(=O)Nc1ccc(Oc2cccc(F)c2)nc1 +C=CCOC(C)C(=O)Nc1ccc(F)c(C(N)=O)c1 +CSc1nc(C)c(CCC(=O)Nc2cccn(C)c2=O)c(C)n1 +CCOc1ccccc1NC(=O)CC(C)n1cccn1 +CCCCCNC(=O)C1CCN(C(=O)NCc2cnn(C)c2)CC1 +CCCNC(=O)C(C)N1CCN(C(=O)CO)CC1 +COc1ccc(C(=O)NC(CO)c2ccccc2)cc1 +CNC(=O)c1ccc(NC(=O)c2cccc(N(C)C)c2)cc1Cl +COc1cc(OC)c(CNC(=O)N2CCOC(C)C2)c(OC)c1 +COC(=O)c1c(-c2ccc(OC(C)C)c(C)c2)noc1N +COc1cccc(CC(=O)NCCNC(C)=O)c1 +Cc1cc(C(=O)CSc2ncn(-c3ccccc3)n2)c(C)s1 +CC(C)c1nc2n(n1)CC(Nc1ncccc1C#N)CC2 +COc1cc(F)c(NC(=O)N(C)CCC(C)O)cc1OC +CCN(CC(=O)NC(C)C)C(=O)CCn1c(=O)oc2ccccc21 +Cc1cc(NC(=O)CNc2cc(F)ccc2C)n(C(C)(C)C)n1 +CC(NC(=O)c1ccc2c(c1)OCCO2)C1CCCO1 +Cc1nc(NC(=O)CCc2ccccc2)ccc1N +CCOC(C)C(=O)Nc1ccc2c(c1)nc(C(C)(C)C)n2C +CCCNC(=O)Cn1c(-c2cccc(Cl)c2)nc(CC)cc1=O +Cc1cc(C(=O)N(C)C2CCCCC2)c2c(C)noc2n1 +Cn1cc(CCC(=O)N2CCN(Cc3ccncc3)CC2)cn1 +CCCn1nccc1C(=O)Nc1cc(C)nc2ccccc12 +Cc1cc(C#N)c(N(C)C)nc1-c1ccc(F)c(F)c1 +Cc1cc(C(=O)NC(C)c2ccc3c(c2)NC(=O)CO3)no1 +O=C(COc1ccccc1F)Nc1ccc2cn[nH]c2c1 +O=C(NCCNc1ccc(C(F)(F)F)cn1)c1ccoc1 +CSc1n[nH]c2ncnc(Nc3ccn(Cc4ccccc4)n3)c12 +C#CCn1c(=O)nc2n1C(=O)N(c1cccc(Cl)c1)C2 +CCc1nc2nc3c(cn2n1)C(=O)CC(c1cccs1)C3 +COC(=O)c1ccc(C(=O)NCc2ccc(OC(C)C)cc2)cc1 +CCCc1nnc(NC(=O)CCCN2CCOC2=O)s1 +Cn1cc(C(=O)NCc2ccc(C(=O)N3CCCCC3)cc2)cn1 +Cc1oc2ncnc(N3CCOCC3)c2c1C(=O)Nc1ccccc1 +Cc1ccc(SCCCCC(=O)N(C)C)nc1 +CCc1ccsc1C(=O)NCC(C)(C)c1ccncc1 +COc1ccc(F)cc1CN1CC(n2cc(C)cn2)C1 +COc1cc(C#N)ccc1C1NCCc2c(C)cccc21 +CC(O)c1cc(Cl)ccc1OCCCCCO +Cc1nnc(-c2csc(S(=O)(=O)N3CCN(C)CC3)c2)o1 +Cc1ccc(C2CC(=O)Nc3c2cnn3C2CCCC2)cc1 +CCc1nnc(-c2ccc(S(=O)(=O)N3CCC(C)CC3)o2)o1 +CCC(C)n1nccc1NC(=O)c1cc2cc(C)ccc2nc1C +Cc1[nH]ccc1C(=O)N1CCC2(CCC(=O)N(CC3CC3)C2)CC1 +O=C(NC(CO)c1ccccc1)c1ccccc1C(F)(F)F +COc1ccc(-c2csc(NC(=O)c3cc(C)no3)n2)cc1OC +CCn1cc(CNc2cccnc2)c2ccccc21 +COc1ccc(CNS(=O)(=O)c2ccc3oc(=O)ccc3c2)cc1 +N#Cc1ccc(-c2ccc(C3OCCO3)cc2)cc1 +COc1cc(C(=O)OCc2nccs2)cc(OC)c1C +CCOC(=O)NCCNC(=O)C1CCN(c2cnccn2)CC1 +COCC(C)Nc1ncnc(Oc2cccc3ccccc23)c1N +C=CCNS(=O)(=O)c1cccc(C(=O)N(C)Cc2ccc(C)o2)c1 +COC(CNC(=O)c1cccc(C(F)(F)F)c1)c1ccsc1 +Cc1cccc(C)c1OCC(=O)N1CCN(c2ccc(O)cc2)CC1 +COC(=O)c1cnn2c1ncc1c(=O)n(-c3ccc(O)cc3)ccc12 +Cc1cc(NC(=O)C(C)Nc2c(C)nn(-c3ccccc3)c2C)no1 +Cc1cc(C)c(C)c(C(=O)CNC(=O)c2ccco2)c1C +COc1ccccc1CCNC(=O)C1CC1(Cl)Cl +CC1CCCC(CNC(=O)C(Cc2ccccc2)NC(N)=O)C1 +Cn1cnc(-c2cccc(NC(=O)c3cc[nH]n3)c2)n1 +CCOc1ccc(S(=O)(=O)Nc2ccccc2)cc1NC(C)=O +CN1CCN(C(=O)COCc2cc(-c3ccco3)on2)CC1 +COCCNC(=O)c1ccc2nc(N3CCCCC3)sc2c1 +CC(Oc1ccccc1C#N)C(=O)Oc1cccc(F)c1 +Cc1cc(C)c(C(=O)N2CCC(c3nc(C)no3)CC2)c(C)c1 +CC(=O)N1CCN(C2COc3c(C)cccc3C2O)CC1 +Cc1nc(-c2ccccc2)sc1CNC(=O)C1CC(=O)N(C)C1 +COC(=O)c1cccc(C2NCCc3c(O)cccc32)n1 +CNC(=O)COC(=O)c1ccccc1SCc1cccs1 +CN(C)C(=O)CNc1ccc(N)c(C(F)(F)F)c1 +CCOCCCNC(=O)C1(C)CCC(=O)N1c1ccc(C)cc1C +Cc1cccc(N(CC(=O)Nc2ccccc2)S(C)(=O)=O)c1C +CC(=O)c1ccc(C)cc1OCCN1CCOCC1 +N#Cc1ccc(-c2ccccn2)nc1SCCN1CCOCC1 +COCCNC(=O)Cc1c(C)c2c(OC)cc(C)cc2oc1=O +O=C1Cc2cc(C(=O)OCCCOc3ccc(F)cc3)ccc2N1 +COc1ccccc1N1CCN(C(=O)c2ccco2)CC1 +Cc1ccc(CN2CCN(C(=O)c3cnc(C)nc3C)CC2=O)cc1 +CN(CCC(F)(F)F)S(=O)(=O)N1CCCCC1 +CNc1ncc(C(=O)NC(C)COC)cc1Cl +COc1ccccc1CNCCc1ccccc1F +CC(=O)Nc1ccc(O)c(C(=O)N2CC3CC4CC(C3)CC2C4)c1 +O=C(Cc1ccc(F)c(F)c1)NCCNC(=O)c1ccc(O)cc1 +CCC(=O)Nc1ccc(CC(=O)N2CCN(C)CC2)cc1 +CC(=O)c1cccc(NC(=O)C2CC3C=CC2C3)c1 +CS(=O)(=O)c1ccc(NS(=O)(=O)c2cccc(C#N)c2)cc1 +CCNS(=O)(=O)c1ccc2c(N(C)C)cccc2c1 +CCOC(=O)CN1C(=O)C2CCCCN2C(=O)c2ccccc21 +CCCCC1C(=O)N(C)CCN1Cc1nc(-c2ccco2)no1 +Cc1cc(C(=O)Nc2cccc(C(=O)N(C)C)n2)nn1-c1ccccc1 +Nc1ccc(-c2ccc(Br)cc2)[nH]c1=O +Cc1nn(CC(=O)N(C)Cc2ccno2)c(=O)c2ccccc12 +CN(C)C(=O)N1CCN(C2CCCc3ccccc32)CC1 +O=S(=O)(NCC1CCCO1)c1ccccc1Br +Cc1ccsc1C(=O)NC(C)c1ccc2c(c1)OCO2 +O=C(CN1CCN(C(=O)c2ccccc2F)CC1)NCC1CCCO1 +CCN1C(=O)C(NC(C)=O)c2c(Cl)ccc(OC)c21 +COC(=O)CCCC(=O)N1CCCN(c2ccc(F)cc2)CC1 +CCc1cccc(C)c1NC(=O)NCc1cccc(OC)c1 +O=C(NC1CCC2(CC1)OCCO2)N1CCc2ccc(O)cc2C1 +N#Cc1ccc(-c2noc(-c3ccccc3F)n2)nc1 +Cc1ccc(C(=O)NCc2nc(-c3ccco3)n[nH]2)s1 +CCOc1ccc(F)c(C(=O)NC2CC(C)(OC)C2(C)C)c1F +Cn1cc(C(=O)N2CCCC2C(=O)OCc2ccccc2)ccc1=O +CN(CC1CCCO1)C(=O)NC1CCN(CC(F)(F)F)C1 +Nc1ccc(Cl)cc1C(=O)OCC1CCCCO1 +CCCc1noc(Cn2nnc(-c3cccs3)n2)n1 +COc1ccccc1NCC(=O)Nc1cccc(C(=O)NC(C)C)c1 +C=CCNC(=O)c1ccc2nc3c(nc2c1)C1CCC3C1 +Cc1cn2c3c(=O)[nH]c(=O)n(C)c3nc2n1-c1ccc(C(N)=O)cc1 +Cc1occc1C(=O)NC(C)c1ccc(NC(=O)c2ccncc2)cc1 +Cc1ccc(CN2CCC3C2CCC(=O)N3CC2CC2)s1 +CC(NC(=O)c1c[nH]nc1-n1cnnn1)c1ccccc1-n1cccn1 +CC(=O)Nc1ccc(NC(=O)N2CCCC(C)C2)c(Cl)c1 +CC1CN(S(=O)(=O)N2CCN(Cc3ccco3)CC2)CC(C)O1 +CCCNC(=O)CSc1ccc(NC(=O)c2cccc(F)c2)nn1 +Cn1cc(CCCOC(=O)c2ccc3ccc(Cl)cc3n2)cn1 +COC(=O)c1cnc(N(C)C(=O)c2cnc3ccc(C)cn23)s1 +CCN(C(=O)C1CC(=O)N(Cc2ccco2)C1)C1CCCCC1 +COc1cccc(-c2cc(NC(=O)N3CCC4(CCC4)C3)n(C)n2)c1 +COc1cc(C)ccc1OCC(O)CNc1cccc(C)c1 +Cc1ccc(C(NS(C)(=O)=O)c2ccccc2)c(C)c1 +O=C(c1sccc1-c1ccccc1)N1CCCC1 +Cc1nc(CCC(=O)N2CCCC(CCc3ccccc3C)C2)n[nH]1 +CNC(=O)C1(C)CCCN1C(=O)CCc1ccc(F)cc1 +Cc1ccc(C(=O)N2CCCC(CNS(N)(=O)=O)C2)cc1F +CCN(CC)C(=O)c1ccc(NC(=O)N2CCCC2)cc1Cl +Cc1ccc(S(=O)(=O)CCS(=O)(=O)c2cccs2)cc1 +CCOC(=O)C1(NC(=O)c2ccc(=O)n(C)n2)CCCC1 +CC1(C)CCC(CNC(=O)c2ccc(-n3cncn3)nc2)CC1 +Cn1nccc1C(=O)Nc1cccc(Cl)c1Cl +COc1ccc(OC)c(-c2nc(NC(=O)c3ccco3)sc2C)c1 +Cn1c(=O)c2cc(C(=O)NC3CCCCC3)sc2n(C)c1=O +O=C(NCc1ccco1)C1CCCN1C(=O)Cn1cnnn1 +Cc1cc(NC(=O)Cn2ccccc2=O)ccc1Oc1cccnc1 +Oc1cc2c(cc1Cl)CNCC2c1ccccc1 +COC(=O)c1cnc2nc(COc3cccc4cccnc34)nn2c1C +Cn1cc(Br)cc1C(=O)Nc1cccc(C(F)(F)F)n1 +COc1cccc(N2C(=O)C(C)(C)CS2(=O)=O)c1 +CCCOc1ccc(CNC(=O)c2n[nH]c(=O)[nH]2)cc1OC +Cn1cc(C(=O)Nc2cccc(CO)c2)c(-c2cccs2)n1 +CCC(NC(=O)N1CC(C)OC(C)C1)c1ccccc1OC(F)F +O=C(CNC(=O)c1ccoc1)NCc1cccc(O)c1 +Cc1cc(NC(=O)CCc2ccccc2F)ccc1N1CCCC1=O +CCOCc1ccc(CNC(=O)c2ccccc2Cl)cc1 +O=C(Nc1cccc2cccnc12)c1ccc(Cl)cc1 +NC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(OC(F)F)cc1 +O=C(NCCNC(=O)C1CC1)Nc1ccc(Cl)cc1F +Cc1noc(C)c1CC(C)NC(=O)NC(C)C(C)CO +CC1CN(CCCC#N)c2ccc(Br)cc2N1 +Cc1occc1C(=O)Nc1ccc(C(=O)N2CC=CC2C(C)C)cc1 +COc1ccc(NC(=O)c2ccccc2CC#N)cc1 +CN(CCc1ccccc1)C(=O)Cc1noc2ccccc12 +Cc1ccc(-c2nc(CNC(=O)Nc3cnccc3C)co2)cc1 +CC(NS(=O)(=O)c1ccc(C#N)cc1)C(=O)N(C)C +COc1cc(OC)cc(C(=O)NCCCn2nc(C)cc2C)c1 +Cn1nnc2cc(C(=O)Nc3cnccn3)ccc21 +CC(C)Nc1nc(-c2ccc(Cl)cc2)c(S(C)(=O)=O)cc1C#N +Nc1cnn(CC(=O)Nc2ccccc2Cl)c1 +Cn1c(N2CC=C(c3ccccc3)CC2)c(C#N)c(=O)n(C)c1=O +O=C(CSc1ccncc1)NCc1ccc(OC2CCCC2)nc1 +Cc1[nH]c(=O)[nH]c(=O)c1CN1CCOC(CCCc2ccccc2)C1 +Cc1ccc(OCC(=O)c2c[nH]c3ccccc23)c(N)c1 +Cc1cccnc1NC(=O)CCc1c(C)c2c(C)nn(C)c2[nH]c1=O +Cc1ccccc1OC(=O)C(C)NC1=NS(=O)(=O)c2ccccc21 +CC(C)(C)n1cc(NC(=O)c2cn(Cc3ccccc3)nn2)cn1 +COc1ccc(F)cc1NC(=O)c1cc(C(C)C)n(C)n1 +CC(=O)N1CCN(C(=O)Cc2coc3cc(C)c(C(C)C)cc23)CC1 +CCOc1ccc(-c2nc(C)c(C(=O)OCC(N)=O)s2)cc1 +NC(=O)CSc1nccn(-c2ccc(Cl)cc2)c1=O +N#CCc1ccc(C(=O)NCc2ccccc2Cl)cc1 +O=C(NCc1ccncc1)Nc1ccc(Br)c(F)c1 +NC(=O)c1ccc(-c2cc(C(F)(F)F)ccn2)cc1 +Cc1nc(C)c(C(=O)N2CCN(C(C#N)C3CCCCC3)CC2)s1 +Cc1c(C(=O)Nc2ccccc2N2CCCC2)[nH]c2c1C(=O)CCC2 +Cc1ccc(CN(CC2CCCO2)C(=O)Nc2ccc(F)cc2)o1 +c1ccc2c(c1)CCCC21CC1CNc1ccc2nnnn2n1 +CC(C)OCCCNc1cnn(C)c(=O)c1Cl +Cc1nc(CN2CC3CN(C(=O)c4cccn4C)CC3C2=O)cs1 +COc1ccc(NC(=O)Nc2nc(C)cc(C)n2)c(OC)c1 +Cc1nccc(N2CCC(Oc3cnccn3)CC2)n1 +CCC(C)n1ncc(C(=O)Nc2cc(Cl)ccc2O)c1C1CC1 +CCC(CC)c1nnc(NC(=O)C2CCOCC2)s1 +CC(C)CNC(=O)c1ccc(SCc2cscn2)cc1 +c1cncc(N2CCC3(CC2)CNc2ccccc23)c1 +CCCNC(=O)CNc1cccc(NC(=O)c2ccccc2)c1 +COc1cc(CC(=O)NCc2cc(C)oc2C)cc(OC)c1OC +CCC(NC(=O)CSc1ccncc1)c1cccs1 +CCN(CC)C(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +O=C(Nc1ccc(OCC2CCOCC2)cc1)c1ccon1 +CS(=O)(=O)c1cccc(OS(=O)(=O)c2ccccc2)c1 +CN(CC1CC1)C(=O)NCCOc1ccc2c(c1)CCC(=O)N2 +Cc1cc2oc(NC(=O)c3ccc(=O)n(C)c3)nc2c(C)c1Cl +CC(=O)Nc1ccc(SC2CCCCC2=O)cc1 +COc1ccc(S(=O)(=O)N2CCCC(CO)C2)cc1OC +N#Cc1cc(NC(=O)C2CCN(CC(F)(F)F)CC2)ccc1Cl +CC(=O)c1ccc(OC(=O)CCC2Cc3ccccc3NC2=O)cc1 +CCN(Cc1cccc(NCc2c(C)nn(C)c2C)c1)C(C)=O +COCc1nc2ccccc2n1CC(O)COc1ccc(C)c(C)c1 +Cc1ccc(SCC(=O)NCC2CCCN2c2cccnn2)cc1 +O=C(Cn1ncccc1=O)Nc1cc(N2CCOCC2)ncn1 +CC(C)(C)c1ncc2c(n1)CN(c1cccc(C(F)(F)F)n1)C2 +COc1ccc2[nH]c(C(=O)NCCC3CN(C)CCO3)cc2c1 +O=C(c1ccccc1O)N(Cc1cccnc1)CC1CCCO1 +Cc1ccc(NCc2nnc(C3CC3)o2)cc1Br +COC(=O)c1cccc(CCNC(=O)C2Cc3cccc(F)c3O2)c1 +CS(=O)(=O)N1CCCC(C(=O)N2CCC3(CC2)OCCO3)C1 +C#CCOCC1CCCN(C(=O)Nc2cccc(C(F)(F)F)c2)C1 +Cn1c(CSc2ncccn2)nnc1SCC(N)=O +CC(NC(=O)NCc1ncn(C)n1)C(=O)N1CCCCC1C +O=C(Nc1nnc(C2CC2)s1)NC1CCCCC1 +Cc1cc(C)c(OCC(=O)Nc2nnn(C)n2)c(Cl)c1 +CCOc1c(Cl)cc(C(=O)Nc2nc(C)cs2)cc1OC +CCNC(=O)N1CCC2(C1)C(=O)Nc1ccc(OC)cc12 +C=CCN(Cc1cccs1)C(=O)c1ccc(OC)cc1 +CCCCNC(=O)c1[nH]c(C)c(C(=O)OC(C)C)c1C +CN(CCN1CCOCC1)C(=O)Nc1cc(F)ccc1Cl +CCOc1ncccc1NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +COc1cccc(NC(=O)NC2C(c3cccnc3)CC(O)C2O)c1 +CCCN(Cc1ccccc1)C(=O)Cc1c(C)noc1C +COCCOc1ncccc1NC(=O)N1CCCC(C)CC1 +CC(C)CNC(=O)c1ccc(N2C(=O)C(C)CS2(=O)=O)cc1 +OCCSc1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CCn1ncnc1C(Nc1nccc(C)n1)C1CC1 +O=C(Nc1ccc(Br)cn1)c1ccc(-n2cnnc2)cc1 +CCC(C)C(C)N(C(=O)c1ccc(-n2ccnn2)cc1)C1CC1 +CC(C)c1cc(C(=O)NCCc2nc(Cc3ccccc3)no2)no1 +CCCC(=O)Nc1cccc(NC(=O)Cc2ccc[nH]2)c1 +N#Cc1nn(-c2ccc3ccccc3c2)c(=O)[nH]c1=O +NS(=O)(=O)CCNC(=O)CCc1cccc(Cl)c1Cl +Cc1cc(C)c2c(c1)CCNC2c1ccc(=O)[nH]c1 +COc1ccccc1C(=O)CCC(=O)NCc1ccco1 +CCCN(C(=O)c1cnc2c(c1)nnn2C)C1CC(OCC)C1(C)C +O=C(CCN1CCOCC1)c1cc(Cl)ccc1Cl +COc1ccc(OCCNC(=O)C2CCCC2)cc1 +Cc1noc2ncc(C(=O)Nc3ccc(N4CCCC4)nc3)cc12 +CCNC(=O)c1ccc(NC(=O)C2CCOc3ccccc32)cc1 +Cc1csc(-n2nc(-c3cccc(N)c3)c3c2CCN(C)C3)n1 +COCc1ccc(C(=O)N2CCN(c3cc(C)cc(C)c3)C(=O)C2)o1 +CCSc1cc(C(=O)Nc2ccc(Cl)cc2C(N)=O)ccn1 +O=C(Nc1cccc(-c2nnnn2C2CC2)c1)C1CC=CCC1 +Fc1ccc(CN(Cc2cccnc2)CC2CCCO2)c(Cl)c1 +Cc1ccccc1CC(C)NC(=O)COc1cccc2c1CCC2=O +CC(C)Oc1ccc(CNC(=O)C2CC=CC2)cc1 +CC(=O)N1CCCC(c2ccc(Br)cn2)C1 +CC1CCCC(CNC(=O)c2ccc3c(c2)NC(=O)C(C)S3)C1 +CCC(C)(C)NC(=O)CCNC(=O)c1ccc(Br)cc1 +Cc1noc(C)c1CN1CCN(C(=O)N2C(C)CCCC2C)CC1 +COc1ccc(C(=O)Nc2ccc(F)cc2C)cc1 +O=C(CC1CCCO1)N1CCN(C(=O)c2ccc(F)cc2F)CC1 +Cc1cc(C)cc(N2CC(C(=O)NCCCn3ccnc3)CC2=O)c1 +CCOC(=O)CNC(=O)C1CSc2nccc(=O)n2C1 +CC(C)n1cnnc1SCC(=O)N(C)Cc1ccccc1F +Cn1nc(C(=O)NCc2ccco2)c2c1-c1cc(F)ccc1SC2 +CC1CC1C(=O)NCc1cn(-c2ccccc2)nn1 +Cc1ccc(F)cc1S(=O)(=O)NCc1ncoc1C +CCOCC(=O)Nc1ccc(C(=O)Nc2ccc(OC)cc2)cc1 +CCN(CCO)S(=O)(=O)N1CCCCCC1 +CC(C)c1cncnc1N1CCCC2(C1)C(=O)N(C)c1ccccc12 +CC(=O)Nc1ccc(Cl)c(NC(=O)c2cn(C)nc2C(C)(C)C)c1 +COc1ccc(-c2nnn(-c3cccc(O)c3)c2N)cc1C +CCCn1c(C)nnc1SCc1nc(-c2cccs2)no1 +N#CCSc1nccn1-c1ccc(Br)cc1 +Cc1ccc(CCC(=O)N2CCNC(=O)C2c2ccccc2)cc1 +Cc1cc(C(=O)Nc2cc(Cl)cc(Cl)c2)on1 +Cc1nc(C2=CN=C(C(=O)N(C)Cc3ccccc3)C2)cs1 +CCOC1CCN(C(=O)NC(C)c2cc(OC)ccc2OC)CC1 +O=C(Cn1cnc2c(cnn2-c2ccccc2)c1=O)N1CCOCC1 +CC1CN(CCCNc2nc3ccccc3o2)CC(C)O1 +COc1cc(C)cc(C(=O)NCC(C)(O)c2ccc(F)cc2)c1O +O=C(COc1ccc(Cl)cc1Cl)NC1CCC(O)CC1 +CN(C)S(=O)(=O)CC(=O)NC(Cc1ccccc1)C(C)(C)C +NC(=O)C1(NC(=O)CSc2nc3ccccc3o2)CCCCC1 +Nc1cnn(CCOc2cc(Cl)cc(Cl)c2)c1 +CCOCCCn1c(=NC(=O)c2scnc2C)[nH]c2ccccc21 +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)NCc1ccncc1 +CC(C)CC(=O)Nc1nc(C(=O)NCc2cccs2)cs1 +CCCCN(CCO)C(=O)Nc1c(C)n(C)n(-c2ccccc2)c1=O +CC(C)(C)C(O)CCNC(=O)CCc1ccccc1 +Cc1nc(CNC2(c3ccc(Cl)cc3)CCOCC2)sc1C +Cc1nc(C(=O)NC2CC3CCC2C3)nn1-c1ccccc1 +O=C(Cc1ccccc1)Nc1nnc(-c2ccncc2)s1 +CCc1nc(C2CCCN2c2ncc(C(N)=O)cc2Cl)no1 +Cc1nccn1-c1cc(CNC(=O)N2CCOCC2C)ccn1 +CCc1noc(C)c1C(=O)OCC(=O)c1ccccc1OC +CCn1nnnc1-c1cccc(NC(=O)NCCCOC)c1 +O=C(Nc1nc(-c2ccc3c(c2)OCO3)cs1)c1ccc[nH]c1=O +COc1cccc(NC(=O)c2cccc(F)c2N)c1 +CCc1cc(=O)n(CC(=O)Nc2cccc(Cl)c2)c(N)n1 +CC(C)CC(NC(=O)C1CCCCC1)C(=O)N1CCc2nocc2C1 +CCCCCN(CC(=O)N1CCNCC1)C(=O)c1ccc(F)cc1 +CCCNC(=O)CSc1c(C)cnc2c1c(=O)n(C)c(=O)n2C +Nc1nc(-c2ccc(F)cc2)ncc1C(=O)N1CCCC1 +COC(=O)CCNC(=O)C(N)c1ccc(C)c(F)c1 +O=C(CN1CCOCC1)N1CCN(C(=O)CN2CCOCC2)CC1 +CCCN1CCN(C(=O)c2ccc(-c3cccs3)nc2)CC1 +CC1CCCCC1OCCNC(=O)Nc1ccc(-n2cncn2)nc1 +O=C(CSc1nnc(-c2ccc[nH]2)o1)N(C1=CCCCC1)C1CC1 +Cc1[nH]nc(-n2cnnc2)c1-c1cccc(Cl)c1 +Nc1cncc(S(=O)(=O)N2CCN(c3ccccn3)CC2)c1 +CNC(=O)COc1ccccc1CNc1ccc(C)cc1 +Nc1c(-c2ccncc2)noc1C(=O)Nc1ccccc1F +Cc1cc(=O)oc2cc(NC(=O)N(C)Cc3ccc(O)cc3)ccc12 +N#CCCCOc1cccc(NC(=O)c2ccccn2)c1 +CN(c1ccc2ccccc2n1)S(=O)(=O)Cc1ccccc1F +CCN1CCN(C(=O)CN(C)S(=O)(=O)c2ccc(C)cc2)CC1 +OCC1(Cc2ccc(F)cc2)CCCN(c2ncccn2)C1 +Cc1[nH]ncc1-c1nc(-c2ccc3c(c2)CCO3)no1 +Cc1cc(C(=O)Nc2cccc(C)c2C(N)=O)sc1C +Cc1cc(C(=O)Nc2n[nH]c(-c3cccc4ccccc34)n2)c(C)o1 +Cc1ccsc1C(=O)Nc1cnc(N2CCCCC2)nc1 +CCc1ncc(C(=O)N2CCCC(O)(CO)CC2)cn1 +COCCn1ccc(NC(=O)Nc2cc(F)ccc2Cl)n1 +C=CCOc1ccc(C(=O)N2CCN(c3ccc(O)cc3)CC2)cc1 +O=C(COc1ccccn1)NCc1cc(Br)cs1 +CCc1nc(C(=O)NCC(N)=O)nn1-c1ccccc1Cl +C=CCNc1oc(COc2ccccc2Cl)nc1C#N +CNc1nc(-c2c(C)n(C)c3ccccc23)cs1 +Cc1n[nH]c(C)c1NC(=O)CNC(=O)c1cccc(Cl)c1 +CCCNC(=O)c1nc2cccnc2n(CC)c1=O +c1ccc2c(c1)oc1c(NC3CC4CCC3O4)ncnc12 +Cc1cccc(C2CCCN2S(=O)(=O)N2CCOCC2)c1 +N#CCCN(C(=O)c1ccsc1)c1ccc2c(c1)OCCO2 +CCOC(=O)CN(CC)S(=O)(=O)c1ccc(F)cc1C +Cc1ccc(N2CCCC3(C2)CN(S(C)(=O)=O)CCO3)nn1 +CNC(=O)C(O)c1cc(Br)cs1 +CCN(C(=O)CSc1nnc(N)n1C)C1CC1 +COc1cccn(CC(=O)N(C)CCCc2cnn(C)c2)c1=O +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)Nc1ccc2ccccc2n1 +COCCNC(=O)c1ccc(Br)cc1F +COc1cc(C(=O)NCc2ccccc2)ccc1OC(C)=O +CSc1nsc(SC2CCc3ccccc3NC2=O)n1 +NC(=O)CCN(Cc1ccccc1)C(=O)CC1CCCO1 +COCCn1nc(C)c(NC(=O)c2ncn(-c3ccccc3)n2)c1C +CC(=O)N1Cc2ccccc2CC1C(=O)Nc1ccccc1F +Cn1ccnc(NC(=O)CN2C(=O)CCc3ccccc32)c1=O +CCc1c(C(=O)N(C)Cc2ccccc2)cnn1Cc1ccccc1 +COc1ccc2oc(CN3CCOC(C#N)C3)cc2c1 +O=C(NCCc1ccsc1)NC1CCOc2ccccc21 +CC(C)CNC(=O)COc1coc(CO)cc1=O +Cc1ccc(CN2CCN(C(=O)c3ccc(C)s3)CC2)s1 +O=C(NCCCO)c1cccc(OCc2cn3ccccc3n2)c1 +Oc1ccnc(SCc2cc(Cl)cc3c2OCOC3)n1 +CCC(O)c1nc2ccccc2n1CCOc1cccc(OC)c1 +COc1ccccc1-c1nn(C)cc1C(=O)OCc1ccoc1C +Cc1nc2ccc3nc(NC(=O)c4snnc4C)sc3c2s1 +CC(C)CCNC(=O)Cn1cnc2nc3c(cc2c1=O)CC(C)CC3 +NC(=O)Cn1cc(NC(=O)CC(c2ccccc2)c2ccccc2)cn1 +COc1ccc(NC(C)=O)cc1NC(=O)CCc1cccc(C)c1 +CCC(C)NC(=O)c1cn[nH]c1-c1cccc(Br)c1 +O=C(c1cccn2ccnc12)N1CCCCC1Cn1cccn1 +CS(=O)(=O)Nc1ccc(NC(=O)c2cc(Cl)ccc2O)cc1 +Cn1cc(S(N)(=O)=O)cc1C(=O)Nc1cccc(CO)c1 +Cc1cccc(C(=O)Nc2c(C)cc(C)cc2N)c1 +CC(=O)c1ccc(NC(=O)CN(C)c2ccccc2)cc1C +CC1CC(C)CN(C(=O)CCc2nc(-c3cccnc3)no2)C1 +CC(O)c1ccc2c(c1)CN(C(=O)C(C)(C)C)CC2 +O=C(NCc1ncc[nH]1)c1ccc(Br)cc1C(F)(F)F +NC(=O)N1CCCN(Cc2cnc(C3CC3)s2)CC1 +COc1cccc(C(=O)Nc2ccccc2C(=O)N2CCCC2)c1 +Cn1cc(CCC(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)cn1 +CC(C)NC(=O)CN1CCc2ccc(Cl)cc2C1 +CCCN1CCc2c(sc3ncn4nc(C)nc4c23)C1 +CCc1nc2n(n1)CCCC2NC(=O)N(Cc1ccc(C)o1)C(C)C +CCCOc1c(OCC)cccc1C1NC(=O)c2ccccc2N1 +O=C(Nc1ccc(-n2cccn2)c(Cl)c1)NC1CCC(O)CC1 +COC(=O)Nc1ccccc1C(=O)NCc1ccccc1 +NC(=O)CSc1nc2c(c(=O)n1-c1ccccc1)C1=C(CCC1)C2 +CCN(C(=O)Cn1c(C)ccc(C#N)c1=O)c1ccccc1 +Cc1c(Cl)cccc1NC(=O)CCNS(C)(=O)=O +COC(=O)C(CC(C)C)NC(=O)c1cc(C)n(C2CC2)c1C +Cc1c(-c2cc(C(F)F)nc3sc(C(N)=O)c(N)c23)cnn1C +COC(=O)C1CCN(C(=O)c2cc(C(C)(C)C)on2)c2ccccc21 +COc1ccc(-c2noc(COC(=O)c3ccccn3)n2)cc1 +O=C(CCc1nc2ncccc2[nH]1)Nc1ccc2cc[nH]c2c1 +O=C(Cn1nnc(-c2ccccc2)n1)c1ccc2c(c1)CCC2 +CC(CNC(=O)Cn1nc2ccccn2c1=O)c1cccs1 +Cc1ccc(N)cc1NC(=O)c1ccc(F)cc1Cl +CNC(=O)c1ccccc1NC(=O)c1cc2c(cc1Cl)OCCO2 +N#CCCN(CCC#N)C(=O)c1cc(F)cc(Br)c1 +CCc1cc(N(C)Cc2cnc(NC)nc2)n2nccc2n1 +Nn1c(SCC(=O)NCC2CCCCC2)nnc1C(F)(F)F +Cc1ccccc1-c1noc2ncnc(NCCO)c12 +C=CCOC(C)C(=O)Nc1cccc(NC(=O)OC)c1 +Fc1cccc(Oc2ncc(Br)cn2)c1 +CC(NC(=O)Nn1cnc2ccccc21)C(=O)NCc1ccccc1 +Cc1ccncc1NC(=O)NCC(C)Oc1cccc(F)c1 +N#CC(NC(=O)COc1ccc(Cl)cc1)c1ccccc1F +Cc1onc(-c2ccccc2Cl)c1C(=O)NC(C)C +Cc1cc(CN(C)C(=O)c2ccnn2C(C)C)n[nH]1 +Cc1ccc(CNC(=O)Cc2nc(-c3ccccn3)n[nH]2)cc1 +Cc1nn(C)c(C)c1CCNC(=O)c1cc2c(s1)CCCCC2 +CCCNC(=O)Nc1cccc(Cn2nc3ccccn3c2=O)c1 +COc1ccc(NC(=O)CSc2ccc(F)c(F)c2)cn1 +CC(=O)Nc1ccc(CNc2cccc(N3CCCC3=O)c2)cc1 +COCC(C)N1CCN(C(=O)COCc2nc(C)no2)CC1 +O=c1[nH]nc(S(=O)(=O)Nc2ccccc2)c(=O)[nH]1 +CCOC(=O)c1cncc(-c2ccc(C#N)cc2)c1 +COCCOc1ccc(S(=O)(=O)N2CCC(C)CC2C)cc1 +O=C(CCOc1ccccc1)NCCc1cn2ccccc2n1 +CCc1onc(C)c1NC(=O)COc1ccccc1F +CCCCNC(=O)C(C)Sc1nnc(-c2ccccc2)o1 +O=C(Nc1cc[nH]n1)c1[nH]nc(C2CC2)c1Br +CN(C)C(=O)c1ccc(CNc2nnc(Cc3ccccc3F)o2)[nH]1 +N#Cc1cc(C(F)(F)F)ccc1NC1CCCC1C(N)=O +Cc1noc(C)c1S(=O)(=O)N1CCN(C(=O)C2CCCO2)CC1 +O=C(CNC(=O)c1cccc(O)c1)Nc1ccccc1-n1cccn1 +CC(CO)NC(=O)C1CC(=O)N(c2ccc(F)cc2F)C1 +O=C(NCC1CCCO1)c1ccc(NC(=O)c2ccncc2)cc1 +CC(C)n1c(CCNC(=O)Cc2ccc[nH]2)nc2ccccc21 +Cc1noc(C)c1C1CCCN1C(=O)c1cnn2cc[nH]c12 +Cn1c(CN2CCCc3cc(F)cc(F)c32)cc(=O)n(C)c1=O +Cc1cc(NC(=O)c2cccc(F)c2)n(C2CCCC2)n1 +C=C(C)Cn1c(=O)nc(N)c2c3c(sc21)CCCCC3 +O=S(=O)(Cc1noc2ccccc12)NCC1Cc2ccccc2O1 +Cc1cc(C)n2nc(C)c(C(=O)N(C)CCC(F)(F)F)c2n1 +CC(=O)C(C)CSc1nnc(NCc2ccc(F)cc2)s1 +NC(=O)COc1cccc(NC(=O)c2cc3ccccc3cc2O)c1 +COc1ccc(CCC(=O)Nc2nnc3n2CCS3)cc1 +O=c1ccc2cc(S(=O)(=O)NCc3ccccn3)ccc2o1 +CCS(=O)(=O)c1cccc(C(=O)OCc2cccs2)c1 +COC(=O)CCNC(=O)COc1ccc(Cl)cc1C +Cc1ccc(NC(=O)c2cc3c(=O)n(C)c(=O)n(C)c3s2)cc1F +CCc1noc(CC)c1CC(=O)Nc1c(C)c(C)nn1C +Cc1ccc(Cn2cccc(C(=O)Nc3cccc(C)n3)c2=O)cc1 +Cc1c(C(=O)NCC(=O)Nc2cccnc2)cnn1-c1ccncc1 +COc1c(Cl)cc(C(=O)NC(C)C)cc1Cl +CC(NCc1ccc2c(c1)OCO2)C(O)c1ccccc1 +Cc1cc(NC(=O)CNc2ccc(N3CCCC3=O)c(F)c2)n(C)n1 +Cc1oc(-c2ccccc2)nc1CC(=O)OCC(=O)N1CCCC1 +CCc1nc(CN2CCN(C(=O)COCc3ccccc3)CC2)no1 +Cc1cc(C)c(C#N)c(N2CCC3(CCC(=O)N(C)CC3)CC2)n1 +O=C(NC1CC1)C1CCc2sc(C(=O)N3CCOCC3)cc2C1 +COCC1(C(=O)NCCn2c(C)cc3ccccc32)CCC1 +COc1ccc2oc(=O)c(C(=O)NC3CCCC3)cc2c1 +COC(=O)c1cnn2c1nnc1c(=O)n(-c3cccc(C)c3)ccc12 +COc1cccc2sc(NC(=O)CCNC(=O)c3ccco3)nc12 +CC1CNC(=Nc2cncc(OCc3ccccc3)n2)N1 +CN(C(=O)Cn1nnn(-c2cccs2)c1=O)c1ccccc1 +CCN(Cc1ccccc1)C(=O)CNC(=O)c1ccc(C)cc1 +N#CCc1cccc(C(=O)NCCc2coc(-c3ccc(F)cc3)n2)c1 +CNc1snc(C)c1C(=O)OCC(=O)NCc1ccc(F)cc1 +Cc1noc2nc(C)n(CC(=O)NCCc3ccco3)c(=O)c12 +NC(=O)Nc1ccc(C(=O)Nc2ccc(F)cc2)cc1 +COc1ccc(-n2c(C)nc3sc4c(c3c2=O)CCCC4)cc1 +CC(COc1cccc(F)c1)OC(=O)C1CC(=O)N(C(C)C)C1 +CCOC(=O)c1c(NC(=O)C2CCCC2)sc(C(C)=O)c1C +Cc1nc(-c2ccccc2)ccc1-c1nc(-c2ccc(C#N)cn2)no1 +CCOc1ccccc1OCC(=O)Nc1ccc(F)c(F)c1 +CC(C)CNC(=O)COC(=O)c1cccc(N(C)C)c1 +Nc1ccc2c(N3CCC(=Cc4ccccc4)CC3)ncnc2n1 +COC(=O)CCC(=O)c1ccc(Oc2ccccc2)cc1 +COc1ccc(NC(=O)C(CC(C)C)NC(N)=O)cc1F +Cn1ccc(C(=O)NCC(=O)NC2CCCCC2)n1 +Cc1cc(CN(C)S(=O)(=O)c2ccc(F)cc2F)no1 +O=C(Oc1ccc(Cl)cc1)C1CN(Cc2ccccc2)CCO1 +CCC1c2ccsc2CCN1C(=O)Nc1ccc(C(C)=O)cn1 +CC(C)CC(C#N)N(C)C(=O)c1ccc2c(c1)OCO2 +CC(C)(C)c1nn(-c2cc(N)ccc2Cl)c(=O)o1 +COC(=O)c1cc(NCC(=O)N2CCOCC2)c(F)cc1F +CCSc1nnc(NCc2ccncc2)s1 +Cc1nc2ccccc2nc1NCc1cccs1 +CC(=O)Nc1nonc1NC(=O)CSc1ncccn1 +C=C(C)c1nc(C#N)c(NCc2ccc(OC)cc2)o1 +O=C(NCCc1ccccc1)c1cccnc1NCc1ccccc1 +C#Cc1cccc(N(CC)C(=O)c2cccc(C(=O)NCCC)c2)c1 +CCCn1ccc(C(=O)Nc2ccc(Cl)cn2)n1 +CC(=O)NCC(=O)N1Cc2ccnn2CC(c2nc(C)no2)C1 +Cc1ccc(C(=O)NCCNC(=O)c2scnc2C2CC2)cc1F +CCCC(C#N)CC(=O)Nc1c(C)cc(C)cc1C +COc1cccc(N2CC(C(=O)Nc3ccc(OC)nc3)CC2=O)c1 +Cc1ccc(=O)n(CC(=O)N2CCc3ccc(Cl)cc3C2)n1 +COc1cn(-c2ccccc2)nc1C(=O)N1CCC1 +CC(C)(C)NC(=O)c1cccc(NC(=O)COc2ccc(F)cc2)c1 +COC(=O)Cc1c(C)nn(-c2ccc(C)cc2)c1C +COc1ccnc(NCCNC(=O)c2ccc(O)cc2)n1 +CSc1ccc(CN2CCc3nc(C)[nH]c(=O)c3CC2)cc1 +COc1c(O)c(Cl)cc2c1C(C(C)NC(C)=O)NCC2 +CC(C)N(Cc1cccnc1)C(=O)c1n[nH]c(N)n1 +COc1ccccc1SCc1ccc(C(=O)N(C)C)cc1 +COc1ccc(C)nc1NC(=O)Cc1cccc(F)c1 +Cc1noc(C)c1CN1CCCN(S(=O)(=O)C2CC2)CC1 +COc1cccc(C(=O)Nc2ccc(C(N)=O)c(Cl)c2)c1 +Cc1ccc(-n2nnc(C(=O)NC3CCCC3)c2C2CC2)cc1 +c1ccc(Cc2nn3c(-c4cnccn4)nnc3s2)cc1 +O=C(NCCNc1ncccn1)c1ccc(C(F)(F)F)nc1 +CC(C)(C)OC(=O)N1CCN(c2ncnc3ccccc23)CC1 +NC(=O)C(NCC(F)(F)F)c1ccccc1F +COc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cc1OC +O=C(c1cc(Cl)ccn1)N1CCCC(CO)C1 +CC(=O)Nc1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +Cn1cc(S(=O)(=O)NC(c2ccccc2)C2CCCCC2)cn1 +N#CC1CN(Cc2ccccc2OCC2CC2)CCO1 +COc1ccc2ccn(Cc3nnc(-c4cccs4)o3)c(=O)c2c1 +Clc1ccc(OCc2nnc3n2CCCCC3)cc1 +Cn1c(=O)c2[nH]c(Cc3ccccc3)nc2n(C)c1=O +COCCc1nc2sc(C)c(-c3ccc(F)cc3)c2c(=O)[nH]1 +CC(C)CC(NC(N)=O)C(=O)Nc1ccc(F)c(Cl)c1 +CN(Cc1cccc(C(N)=O)c1)c1ncccc1C#N +COC(=O)c1nc(-c2ccc(OC)cc2)[nH]c(=O)c1O +Cc1ccc(S(=O)(=O)Oc2cccc(NC(=O)C3CC3)c2)cc1 +CC(Nc1cnn(CC(F)F)c1)c1ccc(N2CCOC2=O)cc1 +Cc1nc(C)c(C(=O)N2CCCc3c(F)cccc32)o1 +O=C(c1ccc2c(c1)OCCO2)N1CCn2c(nnc2C2CC2)C1 +O=C(NCCCn1cccn1)c1cc(N2CCCC2=O)ccc1Cl +Cc1c(F)cccc1NCc1nnc(C(C)(C)C)o1 +O=C(c1ccc(O)c(Cl)c1)N1CCCCCC1 +CCn1cc(C(=O)NCCOc2cccc(NC(C)=O)c2)cn1 +CC(NC(=O)CCNS(C)(=O)=O)C(=O)NC1CCCC1 +O=C(c1ccc(N2CCOCC2)c(F)c1)N(CC(F)(F)F)C1CC1 +Cc1cc2nc(SCC(=O)NCc3ccc(C)o3)n(C)c(=O)c2[nH]1 +COc1cccc(CN2CCN(C(=O)c3cccnc3)CC2)c1 +N#Cc1ccc(S(=O)(=O)CCn2nnc(-c3cccs3)n2)cc1 +COC(=O)N1CCC(CNC(=O)C2CC=CCC2)CC1 +CN(Cc1ccccc1Br)C(=O)NCCc1ccccn1 +CC1CCCC(N(C)C(=O)CCCCNC(N)=O)C1 +Cc1cc(C)cc(-n2ncc3c(NCc4cccnc4)ncnc32)c1 +Cc1cccc(NC2c3ncccc3C(=O)N2Cc2ccco2)c1 +Cn1c(C(=O)NCc2csc(N3CCCC3)n2)cc(=O)n(C)c1=O +CS(=O)(=O)NCC1CCCC2(CCN(Cc3nccs3)C2)O1 +COC(=O)c1cccc(NC(=O)C2CCCN(S(C)(=O)=O)C2)c1 +O=C(Nc1cnc(N2CCCC2)nc1)c1ccc(F)c(F)c1 +COc1cc(NC(=O)Cn2cnc(C3CCC3)cc2=O)cc(OC)c1 +CCOC(=O)N1CCN(C(=O)c2cccc(S(C)(=O)=O)c2)CC1 +Cc1cc(Cl)ccc1NCc1noc(-c2ccoc2)n1 +Cc1nc(C)c(CCC(=O)N(Cc2cccc(F)c2)C2CC2)c(=O)[nH]1 +CC(C)c1ncc(C(=O)Nc2cccc(-c3cn[nH]c3)c2)s1 +COc1cccc(-c2nc3sc(C4CCC4)nn3c2C#N)c1 +CCNC(=O)NC1CCC(OC(=O)CCc2nc(C)no2)CC1 +CC(C)(C)NS(=O)(=O)c1c(Cl)cc(N)cc1Cl +CCCC(C)(C)NC(=O)c1cnc2onc(C)c2c1 +O=C(NCc1ccc2c(c1)OCO2)N1CCCCC1 +CN1CCOC(C(=O)NCC(O)COCC2CC2)C1 +COCCN(CC(C)C)S(=O)(=O)c1c(C)noc1C +CCN(CC1CCOC1)C(=O)C1CCCN(S(C)(=O)=O)C1 +CC1CN(C(=O)CN2C(=O)c3ccccc3S2(=O)=O)CC(C)O1 +Cc1cc(-c2nnc(NC(=O)CCCc3ccccc3)o2)c(C)o1 +Cc1ccc(C(CNS(C)(=O)=O)N2CCOCC2)cc1 +Cc1ccc(CN2CCN(C(=O)c3ccccc3O)CC2)cc1F +Cn1c(=O)ccn(CC(=O)OCCc2c[nH]nc2C(F)(F)F)c1=O +CC(NC(=O)NCCc1ccco1)c1ccncc1 +O=C(Nc1cc(C(F)(F)F)ccc1O)c1ccc2[nH]cnc2c1 +O=S(=O)(Nc1ccc2ccccc2n1)c1cccs1 +Cc1nc2ccc(N)cn2c1C(=O)NCc1ccncc1 +Cc1cc(C)c(NC(=O)Cn2cnc3c(cnn3C)c2=O)c(C)c1 +CCc1ccsc1C(=O)N1CCN(C(=O)Cn2cnnn2)CC1 +O=C(COc1ccccc1Cl)NCc1nc2ccccc2s1 +CC(C)CC(NC(=O)c1ccccn1)C(=O)N(C)C +CCC1c2ccsc2CCN1C(=O)c1cnn(-c2ccccc2)n1 +CC1=CC2(Nc3ccccc3O2)C(C(N)=O)=C(N)O1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1nnc(C2CC2)s1 +Cc1ccc(CC(=O)N(C)CC(=O)Nc2cc(C)on2)cn1 +Cc1ccc(C(CNC(=O)c2ccncc2)OCCO)cc1 +CCn1c(NC)nc2c1c(=O)[nH]c(=O)n2C(C)C +Cn1ccc2c(C(=O)NCC3CCOCC3)cccc21 +COc1ccc(Cl)cc1N(C)Cc1nnc(C(C)C)o1 +CCOc1cc(C(=O)Nc2ccon2)nn1-c1ccccc1 +Cc1ccc(NC(=O)Cc2cccnc2)c(C)c1O +COc1ccc2c(c1OC)C(=O)OC2NC(N)=O +O=C(c1cnc(-c2ccccc2)nc1)N(Cc1ccncc1)C1CC1 +CN(C)C(=O)CNC(=O)c1nccnc1-c1nc2ccccc2s1 +CC(C)NC(=O)C1CCN(Cc2ncccc2C(F)(F)F)CC1 +CN(CC(=O)N1CCCC1)c1ncnc2ccsc12 +O=C(c1cccnc1CC1COc2ccccc2C1)N1CCCC1 +C#Cc1cccc(NC(=O)CNC(=O)c2cc(CCC)c(C)s2)c1 +COc1cccc2sc(N(C)CC(=O)Nc3ncc(C)s3)nc12 +CCCC(=O)NCc1ccn(-c2ccc(OC)cc2)n1 +O=C(Cn1nnc2ccccc2c1=O)OCC(=O)c1ccc[nH]1 +CCCN1C(=O)C2CCC1CN(C(=O)CCc1cccnc1)C2 +Cc1cc(C)cc(C(C)NC(=O)c2ccc(N3CCNC3=O)cc2)c1 +O=c1c2nnc3ncnn3c2ccn1-c1cccnc1 +CC(=O)Nc1ccc(C)c(NC(=O)c2cc3ccccc3c(=O)[nH]2)c1 +Cc1cccc(NC(=O)N2CCCN(c3ncccc3C#N)CC2)c1C +CCC(CNC(=O)c1sc(C)nc1C)c1ccccc1 +CCCC1CC1NC(=O)Cc1c(CC)noc1CC +CN(CC1CCOCC1)c1nc2nonc2nc1NC1CCCC1 +Cc1cccc(C(N)=O)c1NCc1nnc(-c2ccccc2F)o1 +CC(NC(=O)Cn1ccc(=O)[nH]c1=O)c1ccc2c(c1)NC(=O)CO2 +COCc1[nH]nc(C)c1-c1cc(F)cc(OC(C)C)c1 +COC(=O)N(C)c1ccc(NC(=O)NCc2ccc(C)c(F)c2)cc1 +CNC(=O)c1cccc(NC(=O)c2cc3ccccn3n2)c1 +Cc1nn(C)c(C)c1CC(=O)NC1CCN(c2ccccc2)C1=O +Cc1c(CNC(=O)c2scnc2C2CC2)oc2ccccc12 +Nc1ccc2nn(-c3ccc(F)cc3)nc2c1Br +CSc1ccc(CNCC(O)c2ccccc2Cl)cc1 +NS(=O)(=O)c1ccc(Cl)c(C(=O)Nc2ccsc2)c1 +COC(=O)C(C)NC(=O)c1ccn(-c2cccc(C(F)(F)F)c2)n1 +CC(C)(C)c1ccc2c(c1)C(=O)N(CCC#N)CC2 +CC(=O)NC(C(=O)N(CCO)C1CCCC1)C(C)C +Cc1ccc(CNC(=O)NCc2cnn(-c3ccccc3)c2)cc1 +Cc1nnc(-c2ccc(C(=O)Nc3ccnc(N(C)C)n3)cc2)o1 +Cc1ccc(C(=O)NC2CCSc3ccccc32)cc1C +CN(C)c1nccnc1NCC1CCOc2ccccc2C1 +O=C(Cn1c(=O)oc2ccccc21)NCC#Cc1ccccc1Cl +COc1ccc(C)cc1CC(=O)OC(C(N)=O)c1ccccc1 +CCSc1ccc(Cc2nnc(NC(=O)c3ccno3)o2)cc1 +O=C(NC1(c2cccc(Cl)c2)CC1)c1ccoc1 +O=C(CCNC(=O)c1cccs1)NCC(O)C1CC1 +CC(=O)Nc1cc(NCc2cccn2C)ccc1C +CCOC(=O)NCCc1csc(-n2cccn2)n1 +COc1ncccc1C(=O)N(C)CC(=O)Nc1cccc(C)n1 +O=C(NCCc1c[nH]c2ccccc12)c1csc(-c2cnccn2)n1 +COc1ccccc1S(=O)(=O)C(C)C(=O)NCc1ccc(C)cc1 +CNC(=O)c1cccc(CNc2cccc(Br)c2)c1 +CCC1CCC(CNC(=O)N2CCC(N(C)C(C)=O)CC2)CC1 +COC(=O)C1(N(C)C(=O)CCc2ccc(C)o2)CCCCC1 +CCCC(O)c1cc(Cl)c2c(c1)C(CC)C(=O)N2 +C#CCN1CCC(C(=O)Nc2nc(C3CC3)cs2)CC1 +COC(=O)c1ccc(C(=O)N(C)c2cccc3ncccc23)o1 +CS(=O)(=O)c1ccc(NC(=O)c2cc3c(s2)CCC3)cn1 +Cc1cc(S(=O)(=O)N2CCNCC2)ccc1Cl +CC(C)N(C)C(=O)NCC(C)N(C)c1ccccc1 +Cn1c(SCC(=O)Nc2cccc(O)c2)nnc1-c1cccnc1 +O=S(=O)(NCCN1CCOCC1)c1ccc(F)c(F)c1 +Cc1nc(C)c(CC(=O)NCc2nc3ccccc3s2)c(=O)[nH]1 +O=C(NCCc1ccccn1)c1ccc(N2CCCCC2=O)cc1 +O=C(NCCNc1cnccn1)C1CC(=O)N(c2ccccc2)C1 +COC(=O)C(C)(C)NC(=O)COc1ccc(C(C)C)cc1 +COC(=O)C(C)OC(=O)CN1C(=O)CCOc2ccccc21 +O=S(=O)(N1CCOCC1)N(Cc1ccccc1)CC1CCCO1 +CC(NC(=O)NCc1cccc(C#N)c1)c1ccc(-n2cccn2)cc1 +C=CCOc1ccccc1C(=O)Nc1cccc(-c2nnnn2C)c1 +Cc1ccc2[nH]cc(S(=O)(=O)c3ccc(Cl)cc3)c(=O)c2c1 +COCCn1c(N)nc2c1c(=O)n(C)c(=O)n2C +CCNC(=O)CNC(=O)CNC(=O)c1cc(C)nn1CC +Cc1ccc(CCC(=O)NC2(C#N)CCC3(CC2)OCCO3)c(C)c1 +CCC(c1ccccc1)c1nnc(NC(=O)c2cc(C)nn2C)s1 +Cn1c(CCCNc2ncccn2)nc2ccccc21 +CCSc1nnc(C)c2cnn(-c3ccc(F)cc3)c12 +CCSc1nc(NCCO)c2sc3c(c2n1)COC(C)(C)C3 +CC(C)(C)c1csc(Cn2c(=O)c(C#N)cn(C3CC3)c2=O)n1 +Cc1onc(-c2ccccc2)c1C(=O)Nc1sccc1C#N +COc1ccccc1-c1noc(CN2CCCC3(C2)OCCO3)n1 +NC(=O)NCc1ccc(C(=O)N(Cc2cccc(F)c2)C2CC2)cc1 +O=C(c1c[nH]c(=O)cn1)N(Cc1nccs1)C1CC1 +CS(=O)(=O)N1CCC(Nc2ncc(Br)cn2)CC1 +CNC(=O)c1cccc(CNC(=O)c2sccc2OC(F)F)c1 +CCN(CC)C(=O)c1cc(OC)c(OC)cc1C +CCc1ccccc1NC(=O)c1cccc(Cn2cncn2)c1 +Cc1c(C(=O)OCCCNC(N)=O)sc2ccccc12 +O=C(NC1CCSc2ccc(F)cc21)c1ccccc1F +CCC(NC(=O)c1cnn(C(C)C)c1)c1ccnn1C +CC1CC(=O)Nc2c1c(NC(=O)c1nc3ccccc3s1)nn2C +COc1ccc(-c2c(C(=O)NC(C)C)nc3ccccn23)cc1 +Cn1c(SCC(=O)NC(C)(C)C)nc2ccsc2c1=O +Cc1ccc(NC(=O)NCCc2ccccc2F)cc1-n1cnnn1 +COc1ccc(C2CCCN2C(=O)C2COCCO2)cc1OC +COC(=O)c1cc(C(C)(C)C)sc1NC(=O)c1cnccn1 +O=C(CCn1ccccc1=O)NCCNC(=O)c1ccco1 +Cc1cc(-c2c(C)sc(C)c2S(=O)(=O)N2CCCC2)on1 +CC(C)CC1COCCN1CC(=O)NCC(=O)N1CCCC1 +Cc1nn(C)c(C)c1S(=O)(=O)NCC1(C(N)=O)CCOCC1 +COc1ccccc1NC(=O)C(C)Oc1ccc2ccc(=O)oc2c1 +Cc1cc(C)cc(C(=O)NCc2ccccc2F)c1 +CC(=O)NCc1ccc(-c2csc(NCc3ccccc3)n2)o1 +O=c1ccc(C(F)(F)F)cn1Cc1ccc2ccccc2n1 +O=C(Nc1cc(Cl)ccc1F)c1ccncc1F +COc1ccc(-c2noc(-c3ccn4ccnc4c3)n2)cn1 +Cc1ccc(C(C)NC(=O)Nc2cc(F)cc(F)c2)o1 +Cc1cc(C)n(C(C)C(=O)NCCCc2c[nH]c3ccccc23)n1 +O=C(CC1CCCCC1)NCC(=O)Nc1ccc2c(c1)CC(=O)N2 +O=C(NCc1cccc(CO)c1)c1c[nH]nc1-c1ccccc1Cl +Cn1ncc(NCCC2CCCCC2)c(Cl)c1=O +CC(=O)N1CCCN(C(=O)c2cnc3c(c2)c(C)nn3C)CC1 +O=C(Cn1ccc2c(Br)cccc21)NCCCO +CC(C)CNc1cc(N2CCOCC2)cc2nonc12 +CC(C)(C)C(NC(=O)CC1CCOc2ccccc21)C(N)=O +CCCCSc1nnc(SC(C)C(=O)NC)s1 +C=CCCc1csc(-c2ccc(S(=O)(=O)N(C)C)cc2)n1 +CCCCn1nc(C(=O)NC2(C)CCCC2)ccc1=O +COc1ccc(OC)c(C(O)CN2CCCc3ccccc32)c1 +O=C(COc1ccc(NC(=O)c2ccco2)cc1)NC1CCCCC1 +O=C(Nc1cccc(N2CCCC2=O)c1)c1ccc(-n2ccnn2)cc1 +Cc1ccc(NC(=O)c2sc3ncccc3c2N)cc1 +O=C(CCCc1nc(-c2ccccc2)no1)NCc1ccccc1 +CCOC(=O)Cn1nnnc1-c1ccc(Cl)cc1 +N#Cc1c(N)oc(-c2ccccc2)c1-c1ccncc1 +CC(C)NC(=O)CCNC(=O)NCC(C)(C)c1ccc(Cl)cc1 +COC(=O)CNC(=O)c1nnc2ccc(N3CCOCC3)cc2n1 +Cc1ccc(SCCc2nc(CC(=O)NC3CCCC3)no2)cc1 +COCc1ccc(C(=O)Nc2ccc(C(=O)NC(C)C)cc2)o1 +O=C(NCc1ccnc(OC2CCCC2)c1)c1nccc2ccccc12 +CC(NC(=O)CCc1cccs1)c1ccc(S(C)(=O)=O)cc1 +C#CCN1CCN(C(=O)NCc2c(F)c(F)cc(F)c2F)CC1 +c1cncc(-c2ccnc(NCc3csc(N4CCCC4)n3)n2)c1 +Cc1cc(CS(=O)(=O)NC(C)c2ccc(OC(F)F)cc2)on1 +CC1Oc2cc(Br)ccc2N(C)C1=O +O=C(Nc1nnc(C2CCCCC2)s1)c1ccco1 +COc1cc(C)c(NC(=O)NC(C)c2ccc(C#N)cc2)cc1OC +CNC(=O)CSc1nc2cc(Cl)ccc2s1 +CNC(=O)C(C)CN(C)C(=O)Nc1cccc(N2CCCCCC2)c1 +CC(NC(=O)C1CCCN1C(=O)c1ccco1)c1ccncc1 +Cc1cc(C)n(-c2ccccc2NC(=O)N(C)C)n1 +CN(Cc1ccccc1)C(=O)COc1ccccc1F +CC(C)(C)OC(=O)N1CC2(C1)CN(C(=O)OC(C)(C)C)C2 +COc1ccc2c(c1)CN(C(=O)NCC(C)(C)c1ccncc1)CC2 +O=C(c1ccccc1-n1cnnn1)N1CCN(Cc2ccccc2)CC1 +CNC(=O)Cn1cnc(NC(=O)CCc2ccc(Cl)cc2)n1 +COC(=O)c1cccc(C2NCCc3c(O)ccc(C)c32)n1 +Cc1ccsc1CN(C)Cc1nnc(-c2ccco2)o1 +N#Cc1ncn(CCOc2ccc(Cl)cc2Br)n1 +CC1CC1C(=O)N1Cc2cc(C(=O)N(C)C)ccc2C1c1cnco1 +CCCC(=O)N1CCCCC1C(=O)NCc1cccc(OCC)c1 +COc1ccc(F)cc1NC(=O)C1CCCN(S(C)(=O)=O)C1 +CCc1ccccc1NC(=O)C1CCCN1S(C)(=O)=O +CC(C)c1nc2ccccc2n1-c1ncccc1C#N +CC(C)C(NS(=O)(=O)N(C)C)c1ccc2c(c1)OCCO2 +O=C(NCCN1CCCS1(=O)=O)c1cc(-c2ccco2)[nH]n1 +CCC(C)C(NC(=O)c1oc2ccccc2c1C)C(N)=O +Cc1c(Cl)cccc1OCC(=O)NCCc1ccc[nH]1 +O=C(c1cncc(N2CC3C4CCC(C4)C3C2)n1)N1CCCC1 +N#CC(C(=O)c1cccc(NC(=O)C2CC2)c1)c1nc2ccccc2[nH]1 +O=C(c1nnc2ccccc2n1)N1CCN(c2ccc(F)cc2)CC1 +CCC(=O)Nc1c(-c2ccc(OC)c(OC)c2)n[nH]c1CC(C)C +O=C(Nc1ccc(Br)cc1C(F)(F)F)C1CCOC1 +OCC1CCN(c2ncccc2C(F)(F)F)CC1 +O=C(CCNC(=O)C1CCCC1)Nc1ccc(Cl)cn1 +CC(C)C(c1ccccc1S(N)(=O)=O)C(C)O +O=C(NCCCOCC1CCOC1)c1ccc[nH]c1=O +Cc1cc(C)cc(NC(=O)C2CCN(c3cnccn3)CC2)c1 +CCCNC(=O)C(C)S(=O)(=O)c1ccccc1Br +Cc1noc(C)c1COc1cccn(CCO)c1=O +Cc1nc[nH]c1-c1c(-c2ccccc2)ncn1CC(N)=O +CCn1c(=O)c(=O)[nH]c2cc(C(=O)Nc3ccccc3OC)ccc21 +CN(C)C(=O)CN(CC(F)(F)F)C(=O)Cc1ccc(F)cc1F +O=C1CCCN1CCCn1c(=O)[nH]c2ccccc2c1=O +Cn1c(CCNS(=O)(=O)N2CCOCC2)nc2c(F)cccc21 +CCCCNC(=O)C1CCCN(Cc2cnc(C3CCCC3)s2)C1 +O=C(COc1ccc(OCc2ccccc2)cc1)N1CCCC(O)C1 +COc1cccc(OC)c1COC(=O)c1ccc2nncn2c1 +Cc1ncc(CNC(=O)NCc2cnn(C)c2)s1 +Cc1cc(C)n(-c2ccc(Cl)c(C(=O)NC(C)CO)n2)n1 +C#Cc1cccc(NC(=O)CN(C)C(=O)C2(C#N)CCCC2)c1 +CS(=O)(=O)Nc1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1 +O=C(NCCO)Nc1ccc(OCC2CCCO2)cc1 +O=C(NC1=CC2N=C(c3ccncc3)OC2C=C1)c1cccc(F)c1 +CC(=O)N1CCc2nc(-c3cccc(F)c3)nc(C)c2C1 +CCC(=O)Nc1c(Cl)cc(S(N)(=O)=O)cc1Cl +CCNC(=O)CN(C)C(=O)CN(C)c1ccc(Cl)cn1 +COc1cc(Cl)cc2c1OCC(=O)N(C(C)(C)C)C2 +Cc1ccnc(NC(=O)CN(C)C(=O)c2cc(C)n(C3CC3)c2C)c1 +O=C(Nc1cc(F)cc(F)c1)C1CCN(C(=O)c2ccccc2)CC1 +Cc1nn(C)c(C)c1CC(=O)N1CCN(C(=O)OC(C)(C)C)CC1 +O=C(C1CCC1)N1CC2CCC(C1)N(C(=O)c1ccc[nH]c1=O)C2 +Cc1nc(C(=O)N(C)C)ccc1C(=O)OC(C)c1ccccn1 +Cc1ccc(C2COCCN2C(=O)c2cccc(-c3ccoc3)c2)o1 +Cc1noc(C)c1Cn1nnc(-c2ccc(Br)cc2)n1 +O=S(=O)(NCc1cccn1Cc1cccc(F)c1)c1ccccc1 +CN(C)C(=O)C1CCCN(C(=O)C2(c3ccc(F)cc3)CCC2)C1 +Cn1cccc1C(=O)Nc1ccc(Cl)c(Cl)c1 +COCC(NC(=O)c1csc(Cc2ccc(F)cc2)n1)C(N)=O +CCC(C)NC(=O)C(C)Sc1nnc(-c2ccncc2)o1 +CC(C(N)=O)N(C)S(=O)(=O)c1ccc(Br)cc1F +CC(C)OCCC(=O)Nc1ccc(Cl)c(C(=O)N(C)C)c1 +Cc1nn(C)c2nc(N3CCC(C(=O)N4CCCCC4)CC3)sc12 +CCC(C)CNC(=O)C(C1CCCC1)N1CCN(C(=O)C2CC2)CC1 +CC(=O)Nc1cc(NC(=O)N2CCCC(C)C2)ccc1Cl +CCS(=O)(=O)NCCCn1ccc2ccccc21 +Cc1ccc(OCc2cccc(C(=O)NC(C)C3CCCO3)c2)cn1 +Cn1c(=O)c2c(ncn2CC(=O)OCc2ccccc2F)n(C)c1=O +CN(CCCc1nc2ccccc2[nH]1)C(=O)NCc1ccco1 +COc1ccc(CC(=O)N2CCN(CCc3ccccc3)CC2)cc1 +Cc1cnc(C(=O)NC2(c3ccc(F)cc3F)CCOCC2)cn1 +Brc1cccc(-c2cn3cccnc3n2)c1 +CCCCc1nnc(SCC(=O)Nc2cccc(C#N)c2)n1N +O=S(CCSc1ccccn1)c1ccccc1 +COC(C(=O)N1CCOc2nc(C)ccc21)c1ccccc1 +CN(Cc1ccc(F)cc1)C(=O)CSc1ccccc1F +Cc1cc(C)n(C(C)C(=O)NCc2ccccc2)c(=O)n1 +COC(=O)C(NC(=O)C(C)NC(=O)C(C)(C)C)C(C)C +NC1=Nc2nc3ccccc3n2C(c2ccccn2)N1 +CCC(CC)N(C)S(=O)(=O)c1cc(C)cc(N)c1 +Cc1ccc2c(CC(=O)NCCC(=O)N3CCCCC3)coc2c1C +CCOC(=O)C1CCN(c2nc3ncccc3o2)CC1 +COCCC1NCCc2cc(F)cc(Br)c21 +COc1ccc(-c2csc(NC(=O)NCC3CCCO3)n2)cc1 +O=C(c1cccs1)N1CCC(c2nc(-c3ccccn3)no2)CC1 +O=C(CCC(=O)c1ccccc1)Nc1ccn(Cc2cccnc2)n1 +NC(=O)c1ccc(S(=O)(=O)N(Cc2ccsc2)C2CC2)cc1 +COC(=O)C1=C(C)NC(=O)CC1C(=O)Nc1ccccc1F +COC(=O)C1=C(C)Nc2nnnn2C1c1ccccc1C +NC(=O)c1ccc(CSc2ccc(N)cn2)c(F)c1 +OCc1ccc(Br)cc1Br +c1ccc(-c2ccc3c(c2)C(c2ccco2)NCC3)nc1 +Cc1csc(C2CN(Cc3c[nH]nc3-c3ccc(C)o3)CCO2)n1 +CCC(C)C(=O)NC1CC(C)(C)Oc2ccc(C(C)O)cc21 +Nc1cccc(NC(=O)c2cc(Br)ccc2F)c1 +Cc1cc(CNC(=O)c2sc(-c3ccccn3)nc2C)c(C)o1 +Cc1ccc(C(=O)N2CCN(c3ccccc3F)CC2)cc1F +CCC(C)(C)C(=O)NC1CCN(C(=O)c2ccc(C)cc2)CC1 +CCOc1ccccc1-n1nnc(CO)c1-c1cccnc1 +O=C(CCSc1ccccn1)N1CCCS1(=O)=O +COC(=O)C1=C(C)N(C)C(=O)NC1c1ccccn1 +NC(=O)C(c1ccc(F)cc1)N1CCc2sccc2C1 +CCC(C)NC(=O)CC1c2ncccc2C(=O)N1c1cccc(C)c1 +Cc1cc(C(N)c2nc(C(C)C)cs2)c(C)s1 +CC(N(C)C(=O)c1ccc(S(N)(=O)=O)o1)C(C)(C)C +Cc1nn(C)cc1C1CC(O)=Nc2c1cnn2C(C)(C)C +Nc1ccc(Cl)cc1NC(=O)CSc1ccccn1 +CC(CNC(=O)Cc1cccc(C(F)(F)F)c1)c1ccncc1 +CSc1nc(C(=O)Nc2cc(C)nn2C)c2ccccn12 +Cc1ccc(NC(=O)Cn2nnc(C#N)c2C)cc1C +COC(=O)c1cccc(C(=O)NC(C)c2nc3ccccc3[nH]2)n1 +Cc1nnnn1-c1cc(NC(=O)N2CC(C)OC(C)C2)ccc1F +CC1CCCC(NC(=O)CSc2nc(N)c(C#N)cc2C#N)C1C +CC(C)Nc1ccccc1S(=O)(=O)NC1CC1 +O=C(CNC(=O)Nc1nccs1)Nc1ccc(O)cc1 +CCOC(=O)N1CCN(Cc2nnnn2-c2cccc(F)c2)CC1 +O=C(CCc1ccsc1)Nc1ccccc1Cn1cccn1 +CC(C)c1noc(C(C)Nc2ccc(CN3CCCC3=O)cc2)n1 +O=C(CSc1ccncc1)Nc1cc(C(F)(F)F)c[nH]c1=O +Cc1ccc(Cl)cc1NC(=O)c1ccsc1 +O=C(Nc1ccc(Br)cc1Br)C1CCCO1 +Cc1nc(C)c(C(C)N(C)C(=O)c2ccc3c(c2)OCCCO3)s1 +CCOC(=O)c1cc(-c2cc(OC)ccc2OC)nn1C +COc1cccc(CC(=O)Nc2ccc(N)cc2OC)c1 +COC(=O)c1cc(C)nc2cc(C(F)(F)F)nn12 +Cc1ccccc1N1CCCN(C(=O)c2cccc3c2ccn3C)CC1 +COCCCNC(=O)C1CCN(S(=O)(=O)c2ccccc2)CC1 +Cc1cc(C)n(Cc2nc(-c3ccc(-n4nc(C)cc4C)nc3)no2)n1 +OCc1c(-c2ccncc2)nc2c(Cl)cccn12 +CC(NC(=O)c1cccc(OCC(F)F)n1)c1nc2ccccc2[nH]1 +CCOC(=O)Cn1nc(C)cc1NC(=O)c1ccncc1 +COC(=O)C(Sc1nc2ccsc2c(=O)n1C)c1ccccc1 +CCC(C)c1nc2ccc(OCCO)cc2s1 +Cn1ccnc(NC(=O)c2ccn(-c3ccc(Cl)cc3)n2)c1=O +CCNC(=O)c1ccc(NC(=O)c2ccccc2C)cc1 +CCOc1cc(C)nc(N2CCC(C(=O)NCCOC)CC2)n1 +Cc1ccc(O)c(C(=O)Nc2cccc(C(=O)N3CCOCC3)c2)c1 +CCC(=O)C(C)Sc1nc2ccccc2n1CCOC +N#Cc1ccccc1S(=O)(=O)Oc1cccc(F)c1 +CC(C)Cc1noc(CNc2ccc(-c3nnnn3C3CC3)cc2)n1 +O=C(NC1CCCC1)c1ccc(Oc2ccc3nnnn3n2)cc1 +CC(=Cc1ccccc1)CN1Cc2ccccc2CC1c1nnc(C)o1 +Cc1cccnc1CNC(=O)c1ccc(F)cc1F +CC(C)c1ccc(COc2cccn(CC#N)c2=O)cc1 +Cc1nc2c(s1)C(N(C)CC1=CCCOC1)CCC2 +O=C(Cn1ccc(=O)[nH]c1=O)NCCCc1ccccc1 +COc1nccnc1N1CC2c3ccccc3OCC2(CO)C1 +O=C(NC1CCCC1)c1ccc(NC(=O)c2csnn2)cc1 +Cc1cc(C)c(NC(=O)c2cnn3ccccc23)c(C)c1 +O=C(NCCc1ccccn1)c1ccc(-c2cscn2)cc1 +CCCCNC(=O)C(C)S(=O)(=O)c1ncccc1Br +O=C(Nc1cc(Cl)ccc1-n1cncn1)C1Cc2ccccc2O1 +CCC(CC)CS(=O)(=O)NCC1CN2CCCCC2CO1 +COc1cccc2ccc(-c3nn4c(C5CC5)nnc4s3)nc12 +O=C1COC2CN(Cc3ccccn3)CC2N1c1ccccc1 +CCCC(=O)N1CCC(c2cnn(-c3ccc(F)cc3)c2)CC1 +Cc1ncsc1CN1CC(OCc2ccccn2)C2OCCCC21 +O=C(CCCc1ccccc1)N1CCCC1c1ccc[nH]1 +Cc1ccc(CC(=O)Nc2sccc2C(=O)NC2CC2)cc1 +Cc1ccc(CNC(=O)NCc2cnn(C)c2)cn1 +CN(C)C(=O)N1CCC2(CC(=O)N(c3ccc4c(c3)OCO4)C2)C1 +Cc1nc2ccccc2n1CC(=O)Nc1cccc2[nH]ccc12 +CC(=O)c1cc(F)cc(C(=O)Nc2ccccc2)c1 +Cc1nc(CC(=O)NCc2ccc3ccccc3c2)cs1 +O=C(CC1CCCC1)N1CCCC(N2CCNC2=O)C1 +CN1CC(C(=O)Nc2cccc3c2CCCC3)CC1=O +Cc1ccc(F)cc1NC(=O)NCCCc1c(C)noc1C +Cc1nc(CN2CCOC(c3ccc(Cl)cc3)C2)oc1C +NS(=O)(=O)c1ccc(OC2CCCCC2)c(O)c1 +Cc1ccc(C(O)CCCC(=O)N2CCCCC2)c(C)c1 +COc1cc2nc(C#N)cc(C3CC3)c2cc1OC +CCOC(=O)C1CCCN(Cc2cnc3ccc(C)cn23)C1 +N#Cc1ccc(NC(=O)CN2CCOCC2C2CC2)cc1Cl +Cc1cccc(-c2nnc(NC(=O)c3ccc(F)cc3)o2)c1 +CC(=O)Nc1cccc(NC(=O)CC2C=CCC2)c1C +Cc1noc(C)c1C(=O)N1CCC2(CCc3ccccc3C(=O)N2)C1 +CC(=O)NC1CCCN(C(=O)Nc2cccc(-c3ncc(C)o3)c2)C1 +COc1ccccc1C(=O)Cc1nc2ccccc2s1 +O=C(C1Cc2cc(Cl)ccc2O1)N1CCN(c2nccs2)CC1 +COc1ccc(-c2nn3c(=O)cc(-c4cccnc4)[nH]c3c2C)cc1 +CCN(CC)C(=O)CCC(=O)OCC#Cc1ccc(Cl)cc1 +CCOC(=O)CNC(=O)N1CCN(c2cccc(Cl)c2)CC1 +O=C(c1ccccn1)N1CCCC(Cc2nccs2)C1 +CC(C)CCNC(=O)c1ccc2c(=O)n3c(nc2c1)CCCC3 +CCc1nnc(SCC(=O)Nc2cc(C)ccc2OC)n1N +O=C(NCCN1CCOCC1)NCc1ccnc(OC2CCC2)c1 +CN1CCN(C(=O)c2c(N)oc3c2C(=O)CCC3)CC1 +CCN(C(=O)c1nnn(-c2ccc(OC)cc2)n1)c1ccccc1C +O=S(=O)(c1ccccc1)N1CCN(c2ccc3nnnn3n2)CC1 +CSc1cc(C(=O)Nc2nc(-c3cccs3)cs2)ccn1 +COc1ccc2c(O)cc(C(=O)N(C)C)cc2c1OC +COc1cc(C#N)ccc1OCCN1CCOC1=O +O=C(NCc1nnc2ccccn12)Nc1cccc(F)c1F +O=C(NCc1coc(-c2ccccc2)n1)c1cccc(F)c1 +COc1ccc(S(=O)(=O)Nc2cccc(C)c2O)cc1Cl +CCn1cc(NC(=O)Cc2ccc(C)s2)ccc1=O +O=S(=O)(c1c[nH]cn1)N1CCN(c2nc3ccccc3[nH]2)CC1 +CCCc1nc(CN(CC)C(=O)c2cc3ccccn3n2)no1 +O=C(Nc1ccc(OC(=O)C2CC3CCC2O3)cc1)c1ccco1 +Cc1cc(C)n(-c2ccc(NC(=O)NCCC3CCCCO3)cn2)n1 +Cc1ccc2cccc(NC3OC(=O)c4ccccc43)c2n1 +Cc1ccc(-c2ccc(C(=O)N3CCCC3CO)cc2)o1 +COCCNC(=O)CN1CCN(C(=O)Nc2cccc(F)c2)CC1 +Cc1ccc(CNS(=O)(=O)c2ccc3c(c2)OCCO3)s1 +COc1ccc(OC)c(CN2C(=O)C(C)CS2(=O)=O)c1 +Cc1csc(C(C)(C)NC(=O)C2COc3ccc(F)cc3C2)n1 +COc1ccccc1NC(=O)Nc1ccc(C(C)=O)cc1 +CC(C)(C)OC(=O)NCCNc1nc2ccccc2s1 +CCc1ccc(C(N)C(=O)NCCCOC)cc1 +CC(NC(=O)c1cc(=O)c2ccccc2o1)c1ccc(F)cc1F +CCC(CC)C(CNC(=O)Nc1ccncc1)N1CCOCC1 +CN(CC(C)(C)C)C(=O)c1[nH]nc(C2CC2)c1N +Cc1c(NC(=O)c2ccccc2)cccc1NC(=O)c1cccn1C +COc1ccc(-c2cc(C#N)nn2CC(C)C)cc1 +CCOc1ccc(Br)cc1C(=O)NCCCOC +CC(C)(C)OC(=O)N1CCC(Oc2cccc(F)c2F)CC1 +Cc1cc(C#N)ccc1OC(=O)c1cnc(C2CCCO2)s1 +CCn1cnnc1C1CCN(C(=O)C2CC2c2ccccc2F)CC1 +Cc1cc(C)c(NCC(=O)N(C)CC(=O)NC(C)(C)C)c(C)c1 +COC(=O)c1ccc(C(=O)N(Cc2ccsc2)C2CC2)cc1 +Cc1nc(CN2CCC3(CC2)COCCN3CC2CC2)cs1 +Cc1cccc(C)c1NC(=O)CNC(=O)CCC1CCCC1 +Cc1cc(NC(=O)c2cc(Br)c[nH]2)ccn1 +CCNc1ncc(Br)cc1C(=O)N(CCO)C(C)C +O=C(CCCOc1ccc(F)cc1)N1CCCC1c1ccc[nH]1 +Cc1ccc(S(=O)(=O)N=c2cccc(C)[nH]2)c(Br)c1 +Cc1cc(O)c(C(C)C)cc1NC(=O)c1ccc[nH]1 +Cc1noc(-c2ccc(C(=O)NCC(C)Cn3cccn3)cc2)n1 +N#Cc1ccc(C(=O)Nc2nc(-c3ccccc3F)n[nH]2)cc1 +CC(=O)NC1c2ccccc2C(C)(C)C12CCC(=O)CC2 +CC(C)CCN(C)S(=O)(=O)c1cccc(C(N)=O)c1 +CNC(=O)NCC(=O)Nc1cc(F)ccc1OC(C)C +NC(=O)CSc1nnc2n(Cc3ccccc3)c3ccccc3n12 +COCCCNS(=O)(=O)c1cc(N)c(F)cc1F +COC(=O)CCC(=O)Nc1ccc(OC(F)F)cc1 +C=CCCCN(C)S(=O)(=O)c1cccc(F)c1 +Nc1ccccc1OCCS(=O)(=O)c1cccs1 +Cc1ccc(C2NCCc3c(N)cc(F)cc32)s1 +CCOC(=O)N1CCN(C(=O)Nc2ccn(C)n2)CC1 +CC1(CNC(=O)NCC(C)(C)c2ccncc2)COC1 +Cc1nc(C)n(CC2CCCN2Cc2nc3ccccc3s2)n1 +CCOC(=O)c1csc(CNC(=O)c2ccc3cc[nH]c3c2)n1 +CCCC(CCC)C(=O)N1CCC(Oc2ccc(C)nn2)CC1 +Cc1cnc(NC(=O)CN(C)c2ccc(Cl)cn2)s1 +CCc1nnc(NC(=O)CCN2CCOC(C(F)(F)F)C2)s1 +CC(C)C(CNC(=O)NCC1(C)CCCC1)N1CCOCC1 +COC(=O)c1cc(C(C)(C)C)sc1NC(=O)c1cscn1 +C=CCNC(=O)C1CC(=O)N(c2ccc(C)cc2)C1 +COC(=O)c1ccc(-n2ccnc2-c2cc(O)ccc2OC)cc1 +COCCN(c1ccc(C)cc1N)C(C)COC +CCc1ccc(C(C)NC(=O)CSc2nnnn2C2CC2)cc1 +C=CCCOc1cc(Br)ccc1OC +O=C(Nc1cccc(N2CCNC2=O)c1)c1ccccc1Cl +Cc1nc2c(s1)C(N(C)Cc1ccc(-n3cncn3)cc1)CCC2 +CCOC(=O)C1(NS(=O)(=O)c2cccs2)CCCCC1 +CC(C)COCCNc1ncnc2sc3c(c12)CCC3 +CC(C)(C)CC(=O)N1CCN(C(=O)C2CCCCC2)CC1 +O=C(c1ccccc1)N1CCC(c2nnc(C3CC3)o2)CC1 +Cc1ccc(NC(C)c2sc(C)nc2C)c(N)c1 +N#Cc1ccc(CNc2ccccc2C#N)c(F)c1 +CC1CN(CCCCNC(=O)C2CC(=O)N(C)C2)CC(C)O1 +CCOC(=O)c1[nH]c2ccc(Br)cc2c1NC(=O)CC +O=C(CCS(=O)(=O)c1cccc2nonc12)N1CCCCC1 +CC(Cn1cncn1)C(=O)Nc1ccc(-c2cccc(F)c2)cc1 +Cc1cc(C(=O)NC(C#N)c2ccc(C(C)(C)C)cc2)[nH]n1 +Cc1cc(NC(=O)C(C)N2CCN(c3nccs3)CC2)on1 +CCOCC1CCN(C(=O)c2scnc2C2CC2)C1 +CN(C(=O)c1ccc2ccccc2c1)c1ccc(S(C)(=O)=O)cc1 +Cc1ccc2c(c1)NCC(=O)N2Cc1c(C)noc1C +O=C1CCC2(C(=O)NCc3ccco3)Sc3ccccc3N12 +FC(F)c1[nH]nc2c1CC1CN(Cc3cccnc3)CC21 +N#Cc1cccc(CN2Cc3[nH]nc(C(=O)N4CCCC4)c3C2)c1 +O=C(Nc1ccc(-n2cncn2)nc1)c1cc(C2CC2)on1 +Cc1cc(CNC(=O)c2cccc(N)c2)ccc1F +Cc1csc(NC(=O)CCNS(=O)(=O)c2cccs2)n1 +COc1ccccc1CN1CCC(c2nc(-c3ccncc3)no2)C1 +CNc1nc(COCc2ccco2)nc2sccc12 +c1ccc2c(c1)CCN2CCCNc1ccc2nnnn2n1 +COCCCS(=O)(=O)N1CCC2(CCCCCC2)C1 +Cc1ccc(N)cc1S(=O)(=O)NC1CCCC1 +c1ccc2nc(N3CC(n4ccnn4)C3)cnc2c1 +Cc1cccc(OCc2cc(N)n(CCO)n2)c1C +COCC(=O)N1CC(c2ccccc2)NCC1(C)C +O=C1COc2ccc(C(=O)CSc3ccccc3F)cc2N1 +O=C(Cc1n[nH]c(=O)c2ccccc12)NCC(=O)NC1CCCC1 +O=C(CN1C(=O)CCCc2ccccc21)NCC1CCCO1 +CC(Oc1ccc(C#N)cc1)C(=O)c1c[nH]c2ccccc12 +CCOc1ncccc1C(=O)N(CC)c1cccc(F)c1 +CCCCC(=O)Nc1ccc(NC(=O)C2CC2)cn1 +CC(C)OC(=O)C(C)CNC(=O)NCc1ncn(C)n1 +COc1ccccc1OCC(=O)NCC(C)(O)c1ccccc1 +Cc1ccncc1NC(=O)N1CCN(Cc2cccc(Cl)c2)CC1 +Cc1cc(C(C)NC(=O)NCC(=O)OCc2ccccc2)c(C)s1 +CCc1c(C)sc(NC(=O)C(C)Oc2ccccc2C)c1C(N)=O +C#CCNC(=O)c1ccc(-c2cccc(C(F)(F)F)c2)o1 +COc1ccc(C(C)C)cc1CCNC(=O)CC#N +COc1ccc(S(=O)(=O)NCc2ccc(-n3cncn3)cc2)cc1 +Cc1nc2ccccc2n1CCCNC(=O)Nc1ccc(F)cc1F +COCC(=O)Nc1ccc2c(c1)CN(C(C)=O)CC2 +COc1ccc(C(=O)Nc2ccc(N(C)C)cn2)cc1 +Cc1cc(C)c(NC(=O)CNc2c(C)cccc2C(N)=O)c(Cl)c1 +COc1cc(OC)nc(OC(Cc2cnccn2)c2ccccc2)n1 +CNC(=O)c1cc(NC(=O)C2COc3ccc(F)cc3C2)ccc1F +COCc1cc(N(C)Cc2cnc3ccccc3n2)n2nccc2n1 +N#CCn1c(CCO)nc2cc3c(cc21)OCCO3 +Cc1ccn2c(=NC(=O)CNC(=O)CCC(C)C)[nH]nc2c1 +C#Cc1cccc(NC(=O)Cn2nnc(-c3ccc(C)cc3)n2)c1 +NC(=O)C(c1ccccc1)N1CCN(c2ccccc2)CC1 +Cc1cc(C)n(-c2ccccc2CNC(=O)Cc2cccc(O)c2)n1 +Cc1ncc(CNC(=O)N2CCN(c3ccc(F)cc3)CC2)s1 +O=C(COc1cccc(-n2cnnn2)c1)NC1CCCc2ccccc21 +O=c1oc(-c2nccc3ccccc23)nn1Cc1cccnc1 +CCc1noc(-c2ccc(=O)n(CC(=O)Nc3ccccc3)c2)n1 +Cn1nncc1CN(CC(O)c1ccccc1)C1CC1 +CC(C)c1nc(C2CCCN(C(=O)CCc3cccs3)C2)no1 +CC(=O)c1ccc(Sc2nnnn2-c2ccccc2)cc1 +COc1ccc(Cl)cc1NCCC(=O)Nc1ccc(C(N)=O)cc1 +Cc1cccc(OCCCC(=O)NCc2ccc3c(c2)OCO3)c1 +Cn1cc(N2CCC3CN(C(=O)c4ccco4)CC3C2=O)cn1 +Cn1cc(CC(=O)NCc2ccccc2)c2cccnc21 +O=C(Nc1nc(C(=O)NCCc2ccncc2)co1)c1ccccc1 +O=C(NC1CC1)c1ccc(NC(CO)Cc2ccccc2)nc1 +Cc1cccc(C(=O)Nc2cc(S(C)(=O)=O)ccc2C)c1 +Cn1cc(C(=O)Nc2cccc3cccnc23)cn1 +CC(NC(=O)C(Cc1c[nH]c2ccccc12)NC(N)=O)C1CC1 +CC1CC(C)CN(C(=O)c2onc(-c3ccccn3)c2N)C1 +O=C1CN(C(=O)CNC(c2ccc(Cl)cc2)C2CC2)CCN1 +COC(=O)CSc1nc(C)c(Cl)c(C)c1C#N +CCn1nc(C(=O)NCc2ccccc2F)c(=O)c2cc(F)ccc21 +Cc1ocnc1CNC(=O)Nc1ccc2c(c1)OC1(CCCC1)O2 +CCc1nc(CC(=O)Nc2cc(C(C)(C)C)n[nH]2)cs1 +CN1C(=O)CC(NS(C)(=O)=O)C1c1ccc(Cl)cc1 +Cc1ccc(N)c(C(=O)OCc2ccc(C(=O)N3CCCC3)cc2)c1 +Cn1nc(C(F)(F)F)cc1C(=O)NCC(F)(F)F +NC(=O)c1cccc(OC(=O)CCC=Cc2ccccc2)c1 +CS(=O)(=O)N(CCO)c1ccc(Cl)c(Cl)c1 +Nc1c(-c2nc(-c3ccc4c(c3)OCO4)no2)nnn1-c1ccccc1 +C=CCN(Cc1nc(-c2ccccc2)no1)C(=O)c1cccc(C)c1 +COc1cccc(-c2cc(-c3ccc(OC)cc3OC)nc(N)n2)c1 +CC(=O)Nc1cc(NC(=O)C(C)Oc2ccccc2Cl)ccc1C +COCC(=O)Nc1ccccc1-c1nc(-c2ccc(OC)cc2)no1 +O=C(Cc1cccc(Cl)c1)N1CCCC1c1ccco1 +Nc1ccc2oc(C(=O)Nc3ncccn3)cc(=O)c2c1 +Cc1cc(=O)n(C)cc1NC(=O)c1ccc(-c2ccccc2F)o1 +COc1ccc(C(C)OC(=O)CCn2ccccc2=O)cc1F +CC(C)N(CC(N)=O)C(=O)C1CCCN1C(=O)c1cccs1 +CC(C)(C)NC(=O)CNCc1cccc2c1OCCCO2 +COc1ccc(-n2ccc(C(=O)OC3CCCC3OC)n2)cc1 +C#Cc1cccc(NC(=O)CCN2CCOC2=O)c1 +CCn1c(SCC(=O)c2ccc(C)cc2)nnc1-c1cccnc1 +CCOc1cc(C#N)ccc1OCC(=O)Nc1c(C)cccc1CC +COc1cc(N2CCC3C2CC(=O)N3Cc2cccnc2)ncn1 +CCCCC12CN3CC(C)(CN(C1)C3c1ccccn1)C2=O +C=C(C)CN(CC)C(=O)CSc1nc2ccc(OC)cc2[nH]1 +CCN1CCN(C2CCN(C(=O)c3ccccc3C)CC2)C1=O +CCN(Cc1cnn(C)c1)c1nc2nonc2nc1N1CCOCC1 +CCCOc1ccc(S(=O)(=O)NCC2CCCO2)c2ccccc12 +CCn1cnnc1CCNC(=O)C(C)Oc1cc(C)ccc1C +O=C(NCc1ccc(Br)cc1F)NC1CCC(O)CC1 +Cc1nonc1CNC(=O)C(C)Oc1ccccc1F +Cc1cc(C)n2nc(CC(=O)Oc3ccc(Cl)cc3)nc2n1 +CC(C)c1ccc(NC(=O)CSc2nccn2C)cc1 +CC(=O)Nc1cccc(NC(=O)C2(c3ccc(Cl)cc3)CC2)c1 +Cc1ccc(S(=O)(=O)CCC(=O)NCC(F)(F)F)cc1 +CC(C)(C(=O)Nc1nnc(C2CC2)s1)c1ccccc1 +CC(=O)NC(C)(C)c1noc(-c2ccc(Cl)cc2)n1 +CCc1cccc(NC(=O)c2cc(C(N)=O)cn2C)c1 +Cc1cc(=O)oc2cc(OC(C)C(=O)NCc3ccccn3)ccc12 +CCC(CO)N1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +Cc1cc(NC(=O)C2CCCN(CC(F)(F)F)C2)ccn1 +Cc1ccc(CC(=O)NCCOCC(C)C)cn1 +CCc1nc(CCNC(C)c2ccco2)sc1C +O=C(CCCNC(=O)c1ccc(Cl)cc1)Nc1nccs1 +CC(C)(C)OC(=O)Nc1ccc2c(c1)OCCN2 +CNC(=O)CC1CCN(C(=O)c2c[nH]c3cccc(F)c23)CC1 +COc1ccc(NC(=O)c2cncc(Br)c2)c(OC)c1 +CCN(CC)C(=O)C1Cc2ccccc2CN1C(=O)c1ccco1 +CN(C)c1ncncc1NC(=O)CCC(F)(F)F +C#Cc1ccc(CN(Cc2ccccc2)Cc2nccs2)cc1 +CCC(C)N(C)C(=O)Nc1ccccc1OCCOC +CC1(c2nc(C3CCOCC3)nn2CC2COCCO2)CC1 +O=C(CCc1cccnc1)Nc1ccccc1N1CCCCC1 +Cc1cccc(C(=O)NCCNC(=O)c2ccccn2)c1 +CCN(CC)S(=O)(=O)c1ccc(N)c(C(N)=O)c1 +CNS(=O)(=O)c1cnc(NC2CC2)c(Cl)c1 +CCN1CCN(C(=O)c2nc3cccnc3n(CC(C)C)c2=O)CC1 +CCC(=O)c1ccc2c(c1)N(C(C)C(=O)OC)C(=O)C(C)(C)O2 +CCc1nncn1CCNC(=O)NC(c1ccccc1)C1CCC1 +CCNc1nnc(-c2c3c(nn(C)c2=O)CCCC3)s1 +CC(C)=CCC1(CO)CCCN(C(=O)c2cccn2C)C1 +O=C(CN1CCN(c2ccc(O)cc2)CC1)NCc1ccco1 +CN1CCC(C(=O)NC(C2CC2)C2CC2)CC1=O +Cc1ccc2[nH]c(=O)c(CN(C)S(=O)(=O)c3ccccc3)cc2c1 +CCN(CCCNC(=O)NC1CCC(O)CC1)c1ccccc1 +O=c1c2nnc3ncnn3c2ccn1-c1ccc(Cl)cc1Cl +Cc1nn(CC(=O)NCC(C)c2ccccc2)c(=O)c2cccn12 +CCCC(=O)Nc1ccc(CNC(=O)NCc2ccnn2C)cc1 +Cc1cc(C)n(-c2ccccc2NC(=O)Nc2cnn(C)c2)n1 +O=C(Cn1c(-c2ccco2)nc2ccccc21)NCc1ccc(F)cc1 +CC(=O)N1CCC(C(=O)c2ccc(F)c(F)c2)CC1 +COCCC1(C(=O)Nc2cccc(Cl)c2O)CCC1 +Nc1ncccc1C(=O)N1CCN(CCO)CC1 +Cc1ccc2nc(C(=O)NCc3sc(C)nc3C)cn2c1 +O=C(NCCc1ccccn1)c1c[nH]c2c(F)cccc2c1=O +O=C(NCCO)Nc1ccc(OCc2ccccc2)nc1 +CCNc1ncc(C(=O)NCC2COc3cc(OC)ccc3C2)cn1 +CC(O)CNc1ncnc2sc3c(c12)CCCCC3 +Cc1ccsc1CNC(=O)c1cc2ccccc2c(=O)[nH]1 +COC(=O)c1cccc(S(=O)(=O)N(C)C(C)CC#N)c1C +Cn1ccc2c(-c3cc(N)nc(N4CCCC4)n3)ccnc21 +Cc1ccccc1OCC(=O)NC1CCCNC1=O +Cc1nc(N)nc(-c2ccc(OCCc3ccccc3)cc2)c1C(N)=O +COc1ccc(Cl)cc1CNc1cccc(S(C)(=O)=O)c1 +CC(C)C(C(=O)N=c1[nH]nc(-c2ccccc2F)[nH]1)N1CCCC1=O +CCn1c(-c2nc(C(=O)NCC(C)O)cs2)cc2ccccc21 +Cc1nc(CN2CCCc3cc(F)c(F)cc32)oc1C +FC(F)(F)Cc1nc2cccnc2n1Cc1ccccc1 +COc1ccc(C2CC(c3ccc(C)cc3)n3nc(N)nc3N2)cc1 +O=C(c1cnc2sc(N3CCCCC3)nn2c1=O)N1CCOCC1 +CC(C)NC(=O)c1ccc(CNC(=O)c2cc3ccoc3s2)cc1 +O=C(c1ccc(Br)cc1)n1cccn1 +CCCNC(=O)CNC(=O)c1cc(Br)cnc1N +Cc1nn(C)cc1S(=O)(=O)N1CCCC(c2cnccn2)C1 +Cc1ccc(S(=O)(=O)N(CC(C)O)CC(C)O)s1 +CC(=O)c1ccc(C(=O)NCc2cccc(N3CCCC3=O)c2)s1 +COc1ccc(C(=O)NCc2cccc(OC(F)F)c2)nn1 +CC(C)C1(CNC(=O)NCC2CN3CCCCC3CO2)CC1 +Cc1c(C(=O)NCC(=O)Nc2nccs2)nc2c(Cl)cccn12 +Cc1nc(N(C)C)sc1CCNC(=O)Cc1ccccc1O +CC(c1ccc(F)cc1)N(C)C(=O)c1ccc(-n2cncn2)nc1 +COc1ncc(NC(=O)Nc2ccc(F)cc2F)c(N2CCCC2)n1 +CCCCNC(=O)c1ccc(CN2CCCC2=O)cc1 +Cc1ccccc1C(=O)Nc1sc2c(c1C(=O)N(C)C)CCCC2 +COc1ccc(C)cc1NCCc1nc(C)cs1 +Cc1ccc(CNS(=O)(=O)c2cc(F)ccc2F)cc1 +Cc1ccc(C)c(NC(=O)CCn2c(=O)n(C)c3ccccc32)c1 +CNC(=O)C1(C)CN(S(=O)(=O)c2ccc(OC)cc2)CCO1 +Cc1cccc(OCC(C)NS(=O)(=O)N(C)C)c1 +COC(=O)C(NC(=O)c1ccc(C)s1)c1ccc(Cl)c(F)c1 +CCC1(C)Cc2c(sc3nc4n(c(=O)c23)CCS4)CO1 +Cc1nccn1-c1ccc(CNC(=O)c2ccccc2O)cc1F +Cc1nn(-c2ccccc2)nc1C(=O)N1CCC(OCC(C)C)CC1 +CC(C)c1cc(-c2nc(-c3ccncc3)no2)n[nH]1 +COC(=O)c1cccc(-n2nnc(C(N)=O)c2C)c1 +CCC(CO)N1CCN(C(=O)Nc2cccc(C)c2Cl)CC1 +Cc1nc2ccccc2c2nc(-c3nonc3N)nn12 +CC(C)(C)c1csc(CCNS(=O)(=O)c2ccccc2)n1 +COCCOc1cccc(C(=O)N2CCCC(O)C2)c1 +CCOc1cc(F)ccc1NC(=O)c1cncn1-c1ccccc1 +CN(Cc1ccccn1)C(=O)c1ccc(F)cc1F +Cn1nc(S(=O)(=O)CCc2ccccc2)nc1N +CCc1cccc(C)c1NC(=O)COc1cc(=O)n2ccccc2n1 +Cc1cc2[nH]c3c(c(=O)n2n1)CCN(Cc1ccc(F)c(F)c1)CC3 +Cc1cnc(-n2nnc(C(=O)N3c4ccccc4CC3C)c2C)s1 +CC(C)Cc1nc(CNc2ccc(-c3nnnn3C3CC3)cc2)no1 +O=C(OCC1CC(=O)N(C2CC2)C1)C1CCN(CC(F)(F)F)CC1 +CC(C)C(=O)Nc1cccc(NC(=O)Cc2c(F)cccc2F)c1 +CC(C)c1cc(C(=O)N(Cc2ccncc2)CC2CCC(=O)N2)no1 +O=C(Nc1ccccc1OC(F)(F)F)c1csnn1 +Cc1n[nH]c(-c2cccc(CNC(=O)COC3CCCCC3)c2)n1 +Cc1nc2ccccc2n1CC(=O)N1CCNCC1 +Cc1cc(CN(C)C(=O)NCCc2cc(F)cc3c2OCOC3)no1 +O=C(CCN1CCOCC1)c1ccc2c(c1)OCCO2 +NC(=O)c1ccc(NC(=O)COc2ccc(F)cc2Cl)cc1 +CC(=O)NCCNC(=O)COc1ccc(Cl)cc1Cl +CCCCn1ncc(-c2cccc(OC)c2)c(C#N)c1=O +Cc1nc(C(=O)N(C)C)ccc1C(=O)NCC(C)(C)c1ccncc1 +COc1c(NC(=O)Nc2ccc3[nH]ccc3c2)c(C)nn1C +CC1CCCN(C(=O)CC2CSc3nc4c(c(=O)n32)CCCC4)C1 +Cc1nc2ccccc2n1CC(O)c1ccc(OC(F)F)cc1 +O=C(Cc1csc2nc(-c3ccc(F)cc3)cn12)N1CCOCC1 +Cc1csc(C(N)c2cccc(C)c2Cl)n1 +Cc1cccc(S(=O)(=O)NCC2CCCCO2)c1 +Fc1cc(F)c(CN2CCCC(c3nccs3)C2)cc1F +CCc1ccc(CN(Cc2cccnc2)C(=O)c2cnc(C)cn2)cc1 +COc1ccccc1C(=O)NCC(=O)NCc1ccc(Cl)cc1 +Cc1noc(CN2CCn3cccc3C2c2ccccc2)n1 +CC1CCN(C(=O)c2c[nH]nc2-c2ccccc2Cl)CC1 +Cc1nnc(SCc2cc(-c3cccs3)on2)n1N +Cc1cccc(N(C)C(=O)c2ccccc2SCC(N)=O)c1 +O=C1CCC2(c3cc(Cl)ccc3Cl)NCCCN12 +CCn1c(CCNc2ccc3cc[nH]c3n2)nc2ccccc21 +O=C(c1ccccc1N1CCOCC1)N1CC=C(c2ccccc2)CC1 +COc1ccc(C(NS(=O)(=O)Cc2ccon2)C(C)C)cc1 +C#Cc1cccc(NCC(=O)Nc2ccc(F)c(F)c2)c1 +CN(C)C(=O)C1CCCN1C(=O)c1ccc(-n2cccn2)cc1 +CC(=O)Nc1ccc(C#CCNC(=O)c2ccc(N(C)C)cc2)cc1 +Cc1nc2c(cc1C(=O)OC(C)C)c(=O)[nH]c(=O)n2Cc1ccco1 +CCNC(=O)CNC(=O)Nc1ccccc1COCC +COCCNC1CCS(=O)(=O)c2ccc(F)cc21 +CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1Br +CCCC(C)C(=O)c1cc2c(cc1Br)NC(=O)CO2 +CC(C)NC(=O)c1ccc(Cl)c(NC(=O)c2ccc(=O)n(C)c2)c1 +O=C(NCCc1cc(Cl)c2c(c1)OCCO2)c1ccccc1 +CC(C)(C)OC(=O)CSc1nnnn1C1CC1 +Nc1ccnc(Cc2cccc(Br)c2)n1 +CCC(NC(=O)COc1ccccc1OC)c1nc(C)cs1 +Cn1cc(NC(=O)c2ccc(Cn3cccc3)cc2)nn1 +Cc1cccc(C(=O)Nc2ccnn2C2CCCC2)c1 +Cc1nn(C)c(C)c1C(=O)N1CC2CCC1CN(C(=O)N(C)C)C2 +O=C(CC1CCCC1)Nc1ncccc1OCc1ccncc1 +CSc1nc(C(C)C)nc(C)c1C(=O)N1CCCC(O)C1 +CCc1ccc(C(=O)Nc2ccccc2CC(=O)NC)cc1 +CC1CCc2ccccc2N1C(=O)c1cn[nH]c1N +CCC(NCc1nccn1Cc1ccccc1)c1ccc(Cl)cc1 +COc1ccc(CCNC(=O)c2cc(-c3ccco3)on2)cc1OC +Cc1nn(C)c2[nH]nc(NC(=O)c3ccccc3)c12 +Cc1cccc(=O)n1CCCCC(=O)Nc1ccc(C#N)cc1 +CC(CNC(=O)c1ccc(-n2ncc(C#N)c2N)cc1)c1ccccc1 +Cc1cc(Cn2c(=O)c(C#N)cn(C3CC3)c2=O)c2ccccc2n1 +COCc1ccc(C(=O)N(C)CC(=O)NC(C)(C)C)o1 +CN(Cc1nc2c(s1)CCCC2)C(=O)c1c[nH]c2cccc(F)c12 +CCOc1ccc(C2CC(=O)c3ccc(N)cc3O2)cc1 +CCC(CC)N(C)S(=O)(=O)c1cccc(F)c1 +CC(C)CNC(=O)c1ccccc1NC(=O)C(C)C +CCN(CC(C)C)C(=O)CN(C)S(=O)(=O)c1cccs1 +Cc1ccc(CC(=O)Nn2cnc3sc(C)c(C)c3c2=O)s1 +Cn1c(=O)c2[nH]c(CSc3ncc[nH]3)nc2n(C)c1=O +COc1cccc2cc(C(=O)Nc3nc4ccc(F)cn4n3)oc12 +Cc1ccccc1-c1cc(N(C)Cc2nc(N)nc(N(C)C)n2)n[nH]1 +COCCn1c(C)cc(=O)c(O)c1CN(C)CCO +CC(=O)Nc1ccc(SCC(=O)C(C)(C)C)cc1 +COc1ccccc1C(NC(=O)Nc1nccs1)c1ccccn1 +CCc1nnc(NC(=O)c2cnc(C(C)(C)C)nc2N)s1 +CCN(CCC#N)C(=O)COc1ccc(C(C)=O)cc1 +CC(=O)N1CCC2(CC1)C(=O)N(C)c1c(F)cccc12 +COc1cccc(CNn2cnnc2)c1OCc1ccccc1 +COc1ccccc1N1CCN(CC(=O)N2CC(C)CC(C)C2)C1=O +CCc1cc(=O)oc2cc(OCC(=O)N3CCOCC3)ccc12 +Cc1cccc(NC(=O)Cc2cc(-c3ccc4c(c3)OCO4)on2)n1 +C=C(C)CN(C)C(=O)Nc1cc(-c2cccc(OC)c2)nn1C +Cc1c(C(=O)NCC2CCOC2)nnn1-c1ccc(F)c(Cl)c1 +Cc1nnc(CN2CCCc3cc(F)ccc32)n1C +Cc1c(Br)cccc1-c1nc(-c2ccc(C#N)cn2)no1 +CCN(CC1CCCO1)C(=O)CNC(=O)Cc1cccc(F)c1 +COCCCNC(=O)c1cc(C2CC2)nc2onc(C)c12 +O=C(NCC1(O)CCOC1)C1CC1c1ccc(F)c(F)c1 +Cc1cccc(C(=O)OCc2nnnn2-c2ccccc2)c1C +Cc1ccc(-c2nc(C(=O)N3CCCC3C(N)=O)cs2)cc1 +Cc1ccc(CNC(=O)c2cc(-c3cccnc3)nc3ccccc23)o1 +CC(NCC(=O)N1C(C)CCCC1C)c1ccc2c(c1)CCC(=O)N2 +O=C(c1ccc2[nH]cnc2c1)N(Cc1cccc(F)c1)C1CC1 +CC1Cc2cc(C(=O)COc3ccccc3)ccc2N1 +CC(C)N(C)S(=O)(=O)N(C)Cc1cccc(Cl)c1Cl +CC1=NC(NC(=O)C(C)(C)C)(C(F)(F)F)C(=O)N1Cc1ccco1 +COC(=O)c1ccc(NC(=O)NCc2cnn(C)c2)c(C)c1 +O=C(Nc1ccccc1F)c1ccc(N2CCCCS2(=O)=O)cc1 +O=C(CC1C=CCC1)N(Cc1ccco1)Cc1cccs1 +COc1ccc(CCC(=O)N2CCC(O)(C(F)(F)F)C2)cc1OC +O=C(NCCC1CCCO1)N1CCCC1c1cccs1 +CCOc1ccccc1CCC(=O)Nc1ccc(S(N)(=O)=O)cc1 +CSc1nc2n(n1)C(c1ccccc1)CC(C)=N2 +CCOC(=O)C1CC(=O)N(c2ccccc2OC)C1 +CN(CCCC(=O)Nc1ccc2c(c1)CCC2)C(=O)OC(C)(C)C +Cc1nc(C)c(C(=O)N2CC(C(=O)N3CCN(C)CC3)C2)o1 +CCN(CC)C(=O)C1(NC(=O)c2n[nH]c3ccccc23)CCCCC1 +Cc1ccc2c(C(=O)NC(C)(C)CO)nccc2c1N +CCOc1cc(Cl)c(S(=O)(=O)n2ccc(C)n2)cc1Cl +CCCNc1ccc(S(=O)(=O)N2CCOCC2)cc1 +FC(F)(F)c1nnc2ccc(Br)cn12 +COCCn1ccc2ccc(C(=O)Nc3nc(CC(C)C)n[nH]3)cc21 +CN(C)S(=O)(=O)c1ccc(NC(C)(C)C)nc1 +O=C(COc1ccccc1)Nc1nnc(C2=COCCO2)o1 +O=C(NC1CCC(O)CC1)c1cc(C2CC2)nc2ccccc12 +COc1cccc(SCC(=O)NCCN2CCc3ccccc32)c1 +COc1ccc2cc(CCNS(C)(=O)=O)c(=O)[nH]c2c1 +CC(=O)c1ccccc1NCC(=O)N(C)CC(=O)NC1CC1 +CCNS(=O)(=O)C1CCOCC1Cc1ccccc1C#N +O=C(Nc1n[nH]c(N2CCCCC2)n1)c1cccc2ncccc12 +CCOC(=O)CNC(=O)CNC(=O)c1cc(C)oc1C +Cc1nc2cc(NC(=O)C3CCCO3)ccc2n1-c1ccccc1 +CCOC(=O)C1CCN(C(=O)c2cc(Br)c[nH]2)CC1 +Cc1ccc2c(C)c(C(=O)Nc3cc(-c4ccncc4)n[nH]3)oc2c1 +Cc1nc(-c2ccsc2)ccc1C(=O)N(C)Cc1cnn(C)c1 +Cn1c(=O)c2c(ncn2C2C=CC(O)CO2)n(C)c1=O +O=C(Nc1ccc2[nH]cnc2c1)C1CC(=O)N(c2ccccc2)C1 +Cc1ccnc2nc(C(=O)N(Cc3ccc(Cl)cc3)C3CC3)nn12 +Cc1ccc(-c2nnc(COC(=O)c3ccncc3)o2)cc1 +CC(C)C(CNC(=O)c1ccc(S(C)(=O)=O)cc1)c1ccccc1 +N#Cc1ncn(CC(=O)C(C#N)c2nc3cc(Cl)ccc3s2)n1 +O=C(Cc1c(F)cccc1Cl)Nc1nc(-c2cccnc2)cs1 +CC1CCCN(C(=O)c2ccc(F)cc2Cl)C1 +CC(C)(C)OC(=O)NCCNC(=O)C1(c2ccccc2)CC1 +CCC(Oc1ccccc1)C(=O)Nc1cccc(NC(C)=O)c1C +Cc1nc(N2CCCC2)ncc1C(=O)NC1CCCCCC1 +CCN(CC)C1(C#N)CCCOc2ccc(OC)cc21 +CC1c2cccn2CCN1C(=O)Nc1ccc(F)c(Cl)c1 +Cc1nc(-c2nc[nH]n2)sc1C(=O)N(CC1CC1)C1CCCCC1 +Cc1cc(NC(=O)Nc2ccc(Cl)c(Cl)c2)no1 +Cc1noc(C)c1CN(C)C(=O)c1c[nH]c2cccc(F)c12 +O=C(CCC1CC1)N1CCC(Cc2cccc(CO)c2)C1 +CC(C)N(C(=O)c1cccc(OCC(F)F)n1)C1CCC1 +COC(=O)CN1C(=O)C(c2ccccc2)Oc2ccc(C(C)=O)cc21 +O=C(CSc1nnc(-c2ccco2)o1)NCC(=O)c1ccccc1 +COc1ccc2c(c1)c(=O)c(C(=O)Nc1cccc(Cl)c1)cn2C +O=C(COC1CCCC1)OCC(=O)N1CCCc2ccccc21 +CC(=O)Nc1cccc(C(C)NC(=O)CC2=CCCCC2)c1 +O=C(C1COc2ccc(F)cc2C1)N1CCCC(N2CCCC2=O)C1 +Cc1ccc(Cl)cc1N1CCN(C(=O)C(C)C)C(C)C1=O +NC1=Nc2nc3ccccc3n2C(c2cnn(-c3ccccc3)c2)N1 +Cc1ccc(C(O)CCc2nc(C)c(C)s2)cc1C +O=C(Nc1cc(-c2ccccc2F)no1)c1ccncc1 +CC(Oc1ccc2c(c1)CCC2)C(=O)N1CCNCC1 +Cc1oc(C(C)C)cc1C(=O)NCc1cc(N2CCOCC2)ncn1 +COCCCC(=O)NCC(C)(C)N1CC(C)OC(C)C1 +CCCOc1ncccc1CNC(=O)Cc1c(F)cccc1F +Nc1cc(-c2nc(-c3ccsc3)no2)c(F)cc1F +COCCN(C)C(=O)Nc1ccccc1SC1CCCC1 +O=C1CSc2ccc(NC(=O)NCC(F)(F)F)cc2N1 +Cc1nc(SCC(=O)N2CCCCC2C)c2c(C)c(C)sc2n1 +CC(C)S(=O)c1ccc(C(=O)Nc2ccccc2N(C)C)cc1 +Cc1cc(F)ccc1CCNC(=O)Nc1nnc(C(F)F)s1 +O=C(NCCN1CCCCCC1=O)NCc1nnc2n1CCC2 +CN1CCc2nc(NC(=O)c3ccc4c(c3)OCCO4)sc2C1 +O=C(CSc1ccccn1)c1ccc2c(c1)COC2 +CC(CO)(NC(=O)Nc1ccc(OCc2cccnc2)cc1)C1CC1 +CCOCCC(=O)NC(C)c1ccc(-n2cccn2)cc1 +CCCCOc1ccc(C(C)=O)cc1CN1CCOCC1 +Cc1cc(NC(=O)CNc2ccc(F)cc2OCC2CC2)n(C)n1 +Cc1occc1C(=O)Nc1cccc(Cl)c1F +COc1ccc(Cn2cnc(C3CCC3)cc2=O)cc1Br +COC(=O)C(C)C(O)c1ccc(OC(F)F)cc1 +Cc1cc(C)c(C(=O)N(C)Cc2nc(-c3ccncc3)no2)c(=O)[nH]1 +COc1cc(C(=O)N2CCN(C(=O)c3cccs3)CC2)ccc1C +O=C(c1nnc2ccccc2n1)N1CCN(c2ncccn2)CC1 +Cc1ccccc1-n1nccc1NC(=O)C1CC1c1cccnc1 +C=CCn1cc(CNCc2[nH]cc(C)c(=O)c2C)c(C)n1 +COCCN(c1ccc2scnc2c1N)C1CC1 +C=CCNc1ccc(S(=O)(=O)N2CCCCCC2)cc1 +CCOCCCNC(=O)NC(C)c1ccc(F)c(F)c1 +CCCNC(=O)CN(C)C(=O)c1ccc(=O)n(CCC)n1 +Cc1cc(C)nc(NC(=O)COc2ccc(Br)cc2)n1 +CNS(=O)(=O)C1CCN(C(=O)c2cc(SC)ccc2C)CC1 +CC(=O)N1CCC(C(=O)N(C)C(C)c2ccc(C)cc2)CC1 +O=C(OC1CCCCC1)C1CC(=O)N(CC(F)(F)F)C1 +COc1ccc(C(C)NC(=O)Nc2cnccc2C)cc1F +Cc1noc(C)c1C(=O)NCc1ccc(N(C)c2ccccc2)nc1 +Nc1cccc(Cl)c1Sc1nnnn1C1CC1 +CCCc1cc(C(=O)Nc2ccccc2C(=O)NC)sc1C +O=C(OCc1noc(-c2cccc(Cl)c2)n1)c1ccncc1 +CCNC(=O)CN(CC)C(=O)c1cnn(-c2ccncc2)c1C +Fc1ccccc1CCNc1ncnc2[nH]cnc12 +CC1COCC(C)N1C(=O)c1ccc(-n2cncn2)cc1 +CC(C)(C)NC(=O)C1(c2cc(-c3ccccc3)on2)CC1 +CC(C)NC(=O)N1CCC(N2CCCC2=O)CC1 +O=C(Nc1cc(N2CCCCC2)ncn1)c1ccc2c(c1)OCO2 +COc1ccc(-c2n[nH]c(SC(C)c3cccnc3)n2)c(OC)c1 +O=C(c1nc(-c2ccc(F)cc2)no1)N1CCC(O)CC1 +Cc1csc(NC(=O)COC(=O)c2cc3c(s2)CCCC3)n1 +COc1ccc(C(=O)Nc2ccc(F)cc2Br)nn1 +O=C(NCC(F)(F)F)C1CCN(C(=O)c2ccccc2)CC1 +Oc1cc(F)c2c(c1)C(c1cncs1)NCC2 +CCCc1nc(C)c(COc2ccccc2N)s1 +COc1cc(CN2CCOC3(CCCC3)C2)ccc1OC(=O)C1CC1 +Cc1cc(C(=O)Nc2ccncc2)cc(S(=O)(=O)N(C)C)c1C +O=C(Nc1ccccc1N1CCCC1=O)c1cc(Cl)ccn1 +CC(C)C(=O)Nc1ccc(NC(=O)COc2ccccc2F)cc1 +Cc1cc(NCCCCc2ccccn2)n2nc(C)cc2n1 +COc1cccc2[nH]cc(CC(=O)Nc3c(C)cc(C)nc3C)c12 +O=C(COc1ccc(Br)cc1Br)NC1CC1 +COc1ccc2c(CN(C)Cc3ccoc3C)cc(=O)oc2c1 +O=C(CCC1CCCC1)N1CC2CCCN2c2ncccc21 +Cc1noc2nc(C3CC3)cc(C(=O)Nc3ccccc3)c12 +COc1ccc(NC(=O)c2cccc(CC#N)c2)cc1 +CCC(=O)N1CCC(c2nc3cccnc3n2CC)C1 +COCCCN(C)S(=O)(=O)c1cccc(NC(C)=O)c1 +Cc1ccccc1CNc1ccc(N)c2nonc12 +Cc1n[nH]c(-c2cccc(CNC(=O)c3ccc4ccccc4c3)c2)n1 +CC(C)Nc1ncc(Br)c2c(N)cccc12 +Cc1cccc(NCc2nsc(N(C)C)n2)c1Cl +COc1cccc(C(=O)N(C)Cc2cccnc2)c1F +C#Cc1cccc(NC(=O)Cc2c(C)noc2C)c1 +Cc1cnc(NC(=O)CSc2nnc(C)n2-c2ccccc2)s1 +Cn1nnc2c(N3CCN(C(=O)c4ccccc4F)CC3)ncnc21 +C#CCOC(=O)C(C)CS(=O)(=O)c1ccc(Br)cc1 +CN(Cc1nnc2n1CCC2)C(=O)c1cscn1 +Cc1cc(C)n(-c2cncc(NCC(C)(C)N3CCOCC3)n2)n1 +Nc1ccc2c(c1)N(CCO)C(=O)C(Cc1ccc(F)cc1)O2 +COc1ccc(SCCCC(=O)Nc2cc(C)nn2C)cc1 +COC(=O)CCSc1nnc(-c2sc(C)nc2C)o1 +O=C(NC1CCC(O)CC1)c1cccc(N2CCOC2=O)c1 +CCc1nc(COC(=O)CNC(=O)c2ccc(C)s2)cs1 +Cc1noc(C2CCOC3CCN(C(=O)c4cccn4C)CC32)n1 +COC(=O)c1cccc(CCNC(=O)N2CCC3OCCCC3C2)c1 +COC(=O)C(C)(C)N1CCN(c2ccccc2)CC1 +CCCn1nnc(CO)c1-c1ccc(Cl)c(Cl)c1 +CN(C)C(=O)Cc1ccc(NC(=O)Cc2ccc(F)cc2)cc1 +COc1ccc(C(NC(=O)N2CCCC2CO)C2CCOCC2)cc1 +CCc1onc(C)c1NC(=O)C1CCCCN1C(=O)c1cccnc1 +Cc1cccc(-n2ncc(C(=O)NCc3ccco3)c2C(F)(F)F)c1 +COc1cccc(N2CCN(Cc3cc(C#N)ccc3F)CC2)c1 +CNC(=O)c1ccccc1NC1CCN(c2ccccc2Cl)C1=O +CS(=O)c1ccc(CNc2cnn(-c3ncccn3)c2)cc1 +O=C(NCCOc1cccnc1)c1cnn(-c2ccccc2)c1 +CCOC(=O)c1cc(-c2ccc(OC)cc2OC)[nH]c1N +Cc1nc2c(cnn2-c2ccccc2)c(=O)n1CCc1ccccc1 +CC1CN(c2ccc(S(=O)(=O)N3CCCCC3)cn2)CC(C)O1 +CCN(CC)C(=O)Nc1cc(Cl)ccc1N1CCOCC1 +CS(=O)c1nncn1Cc1ccc(OCC(F)(F)F)cc1 +CC(C)C(=O)N1CCN(C(=O)c2cc3cccnn3n2)CC1 +COC(=O)CNS(=O)(=O)c1scc(Cl)c1C(=O)OC +Cc1nn2c(=O)c(C)c(C)[nH]c2c1-c1cccc(Cl)c1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(OC(F)F)c(Cl)c1 +COc1ccc(C(C)(C)C)cc1C(=O)CNC(C)=O +O=C(COC(=O)C1(c2ccc(Cl)cc2)CCCC1)NC1CC1 +COc1ccccc1CNC(=O)c1cccc(N)c1C +Cc1ccc(SC2CCCC2)c(C(=O)N2CCC(O)CC2)c1 +Cc1ccc(NC(=O)N(C)C)c(C(=O)Nc2cccc(F)c2)c1 +COC1CCCC1OC(=O)c1ncn(-c2ccccc2)n1 +Cc1cccc(C(=O)NCc2ccccc2N2CCOCC2)c1O +Cc1ccc(NC(=O)COC(=O)CCC2CCCO2)c(Cl)c1 +CC(C)(C)c1nnc(SCc2nc(-c3ccsc3)no2)o1 +Cc1cc(C)c(C(=O)N2CCCCC2CCN2CCCC2=O)cn1 +CCS(=O)(=O)NCCSc1nc(-c2ccccn2)n[nH]1 +CS(=O)(=O)Nc1ccc(NC(=O)Cc2noc3ccccc23)cc1 +O=C(NCC(O)c1ccccc1F)Nc1cnn(CC(F)F)c1 +CC(C)n1ccc(=O)nc1SCCCN1CCOCC1 +Cn1nnc2cc(-c3noc(COc4ccccc4)n3)ccc21 +C=C(C)c1cccc(C(C)(C)NC(=O)NCCCN2CCOCC2)c1 +COC(=O)c1cc(C(C)C)sc1NC(=O)c1cccnc1 +CN(Cc1cc(F)cc2cccnc12)S(=O)(=O)c1ccccc1F +CC1(C)Oc2ccc(NC(=O)NCC(=O)Nc3cccnc3)cc2O1 +C=CCn1c(SCC(N)=O)nc2sc(CC)cc2c1=O +CCOc1cc(C)c(C2NCCN(C)C2=O)cc1C +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)COc1ccccn1 +CCn1nc(C)cc1-c1nnc(CCC(=O)NC(C)C)o1 +CCCCN(C)S(=O)(=O)c1ccc2c(c1)CNCC2 +Cc1ccc(OCCCC(=O)NCc2nc(C)sc2C)c(C)c1 +CC1CCN(c2nnc(NC(=O)Nc3ccc(F)cc3)s2)CC1 +Cc1ccn2cc(C(=O)NCC(=O)Nc3cccc(C)c3C)nc2c1 +Cc1cccc(NC(=O)CNC(=O)c2ccc3[nH]nnc3c2)c1C +CCn1cc(NC(=O)NCc2cccs2)c2ccccc21 +N#CCCN(Cc1ccco1)C(=O)Nc1ccc(Cl)cc1Cl +COc1ccc(-c2ncc(C(=O)N(C)Cc3ncnn3C)s2)cc1 +CCCNC(=O)CNS(=O)(=O)c1ccc2ccccc2c1 +CC(C)N(C)C(=O)CN1CCOC(c2ccc(Cl)c(Cl)c2)C1 +CCNc1nnc(SCc2cn3ccccc3n2)s1 +CCOc1cc(NC(=O)NCc2ccccc2)ccc1OC +OCCCn1c(-c2cccnc2)nc2cc3c(cc21)OCO3 +COc1ccc(NC(=O)Cn2nc(C)c(C(C)=O)c2C)cc1 +Cc1cccc(C(C)C)c1NC(=O)CCc1cn(C)nc1C +CC(NC(=O)c1csc(C(=O)NC2CC2)n1)c1ccc(F)cc1 +CN(CC1(c2ccc(Br)cc2)CC1)C(=O)C1(C#N)CCC1 +CCS(=O)(=O)c1nnn(CCOc2ccc(C)cc2)c1N +Cc1c(C(=O)N(C)C)sc2ncn3nc(-c4ccco4)nc3c12 +CCc1cc(NC2c3ccccc3CC2O)n2ncnc2n1 +COc1cc(C)ccc1OCC(=O)OCc1ccccc1 +Cc1cc(-c2nnc(CN(CC(C)C)c3cccc(O)c3)o2)c(C)o1 +Cn1nc(C(=O)Nc2ccc(Br)cc2O)ccc1=O +CCC(OC1CCCCC1)C(=O)NCc1nnnn1C1CC1 +Cc1ccc(Br)c(NCC(=O)N(C)C2CC2)c1 +CC(C)n1nccc1NS(=O)(=O)c1ccccc1C#N +Cc1nc(CNS(=O)(=O)c2ccc(F)c(F)c2)cs1 +CCc1ccc(CC(=O)Nc2cc(Br)c(=O)n(C)c2)cc1 +OCCN(Cc1cccnc1)Cc1csc(-c2ccccn2)n1 +CC(=O)NCC(=O)N(Cc1ccco1)Cc1cccs1 +COc1ccccc1CNC(=O)c1c(Cl)cnn1C +Cc1ccn(-c2ccccc2NCc2nc3ccccc3n2C)n1 +CC(C)CNC(=O)c1ccccc1NC(=O)CSc1ncccn1 +COc1c(C2CCCN2C(=O)c2cnc(C)cn2)c(C)nn1C +CC(NC(=O)c1cccc(F)c1)c1nc2ccccc2[nH]1 +CC(C)C(NC(=O)c1ccc(-n2ccnc2)nn1)c1ccc(F)cc1 +CS(=O)(=O)c1nc2ccccc2n1Cc1ccc(C(N)=O)cc1 +CC(C)Nc1ccc(C(=O)N2CCC(OC3CCCCC3)CC2)cn1 +CCCOc1cccc(CNC(=O)CN(C)C(C)=O)c1 +Fc1ccccc1-n1cc(-c2ccnc(NCC(F)F)n2)cn1 +CC(C)OCCC(=O)N(CC1CN(C)CCO1)c1nccs1 +O=C(NCc1cccc(O)c1)Nc1ccccc1Cl +O=C(OCCCc1cccnc1)c1ccc(F)c(F)c1F +Cc1nc2c(c(=O)n1C)CCN(C(=O)Nc1c(F)cccc1F)CC2 +CC1CCCN1C(=O)c1cc(-c2ccc3c(c2)OCO3)on1 +Cn1ncc(NCCNc2ccc3ccccc3n2)c(Cl)c1=O +CNc1nc(CNC(=O)Nc2ccn(CCOC)n2)cs1 +CCOC(=O)CNC(=O)c1cccnc1SC +CC(C)(C)CC(=O)Nc1cc(F)c(S(C)(=O)=O)c(F)c1 +COc1ccc(S(=O)(=O)C2CN(C(=O)CC3CCCC3)C2)cc1 +O=C(c1ccccc1)C1CCN(C(=O)C2CCCO2)CC1 +C=CCN(C(=O)c1coc(S(=O)(=O)N(C)C)c1)c1ccccc1 +CCCNC(=O)CNC(=O)NCc1cscn1 +CCOC(=O)C1CCC(O)N1C(=O)OC(C)(C)C +Cc1ccsc1C(=O)OCC(=O)NC1CCCCC1 +O=C(NCC(O)(c1cccs1)C1CC1)c1ccc2c(c1)OCO2 +O=C(Nc1nnc(-c2ccncc2)s1)c1ccc(F)c(F)c1 +CC(C)(C)OC(=O)N1CCN(CCNC(=O)c2ccsc2)CC1 +Cc1cc(C)n(-c2ccc(C(=O)NCC(=O)OC(C)(C)C)cn2)n1 +COc1ccc(C)cc1NC1=Nc2cc(N)ccc2OC1C +Nc1nc(N)nc(COC(=O)CCc2ccc(F)cc2)n1 +Cc1cc(NCCc2ccc(O)cc2)n2nc(C)cc2n1 +COc1ccc(C(=O)OCC(=O)Nc2ccccc2C(C)=O)cc1 +CCC(CC)(C(=O)Nc1cnn(CC(N)=O)c1)c1ccc(Cl)cc1 +O=C(Cc1ccon1)NC(C(=O)N1CCCCC1)c1ccccc1 +Nc1nc(N)nc(Cn2nc(-c3ccc(F)cc3)oc2=O)n1 +Cc1nccn1-c1ncccc1NC(=O)c1cn(-c2ccccc2)nn1 +Cc1nc(N(C)CCCCN2CCOCC2)c2c(C)nn(C)c2n1 +CC(C)OC(=O)C1C2C=CC3(CN(Cc4ccco4)C(=O)C13)O2 +Cc1cc(F)ccc1NC(=O)c1cnn2c1CCCC2 +CC(C)C(NC(=O)Nc1ccccc1)C(=O)N1CCC1 +O=C(CC1CCCC1)NCCn1cnc(-c2ccc(F)cc2)cc1=O +COc1ccc(C(O)C(C)NC(=O)CNC(=O)c2cccs2)cc1 +Cc1ccc(CNC(=O)CCc2ccccn2)cn1 +Fc1ccc(Cl)cc1CNc1nnc(-c2ccncc2)o1 +CC(C)(C)NC(=O)COc1ncnc2ccc(Br)cc12 +Cc1ccc(NC(=O)N2CCCC2C(=O)Nc2ccccc2)cc1 +Nc1ccc2oc(-c3ccc(F)c(Cl)c3)nc2c1 +Cc1cccc(NC(=O)C(C)N2CCN(c3ccccc3)CC2)c1 +Cc1cnn(CC2CCCCN2C(=O)c2cc(F)cc3[nH]cnc23)c1 +Cc1ccc(C)c(S(=O)(=O)NC(C(N)=O)c2ccccc2)c1 +CCc1ncc(C(=O)N2CCC(CCc3ccccc3)CC2)cn1 +CC(=O)c1ccc(S(=O)(=O)NCC(C)(O)C2CC2)cc1 +COc1ccc(C(=O)CCC(=O)N2CCc3ccccc32)cc1OC +N#Cc1cc(NC(=O)c2ccc(F)cc2)ccc1Cl +O=C(CN1CCCOC1=O)Nc1cccn(Cc2ccccc2)c1=O +CCn1nc(C(=O)N2CCC(C)CC2)c2ccccc2c1=O +O=C(NCCc1nc2cccnc2n1-c1ccccc1)c1ccccc1 +CC1CC(OC(=O)c2ccc3c(c2)CCC(=O)N3)C(=O)O1 +Cn1ccnc(NC(=O)C2(c3cccc(Br)c3)CC2)c1=O +COc1ccc(C(=O)OCc2ccc(F)cc2)nn1 +CCn1cc(Nc2nc(C(F)(F)F)nc3ccccc23)cn1 +O=C(CCc1ccccn1)NC1(C(=O)NCC2CC2)CCCC1 +CCNc1ccnc(-c2cccc(OC(C)C)c2)n1 +O=C(CC1COCC2CN(Cc3nccs3)CC12)NCC1CC1 +O=C(NCc1ccc(-c2ccn[nH]2)cc1)c1ccc(N2CCCC2)nn1 +CCCCN(CC)C(=O)c1onc(-c2cccc(F)c2)c1N +CC(Nc1cc(C(C)C)nc2ncnn12)C(=O)N1CCOCC1 +CCCc1nc(N(C)Cc2ncccc2C)c2cnn(C)c2n1 +CCSc1ccccc1C(=O)Nc1cc(C)nn1C(C)C +CC1CCOCCN1C(=O)NCc1cc(=O)[nH]c2ccccc12 +CC(=O)Nc1ccc(F)c(NC(=O)Cc2c[nH]c3ccccc23)c1 +CC(C)n1nc(C(=O)NCC(=O)OC(C)(C)C)c2ccccc2c1=O +O=C(NCC(=O)N1CCCc2cccc(O)c21)c1cccc(F)c1 +COc1ccc(C(C#N)NCc2cccnc2)cc1OC +CCC1(CNC(=O)Nc2cc(-c3ncco3)ccc2C)CC1 +CCc1cc(NCc2cnn(CC)c2)n2nc(C)c(C)c2n1 +c1cnc2nc(SCCOC3CCCCCC3)nn2c1 +CCc1[nH]nc(NC(=O)Nc2cccc(C(C)=O)c2)c1C +CCOc1ccc(OC)cc1NC(=O)c1c(C)cc(C)[nH]c1=O +Cc1cccc(NC(=O)c2cc3ccc(Cl)cc3n2C)n1 +COc1cc(N)c(C#N)cc1OCc1ccccc1 +O=C(c1ccco1)N1CC(S(=O)(=O)c2ccc(Cl)cc2)C1 +CCC(CO)NC(=O)NC1CCN(c2cccc(Cl)c2)C1 +Cc1c(C(C)NC(=O)CCCNC(=O)C2CC2)oc2ccc(F)cc12 +COCCNC(=O)C(C)Oc1ccc(Cl)cc1C +COc1ccccc1NC(=O)CN1CCN(C(=O)c2ccoc2)CC1 +COC(=O)C1c2ccsc2CCN1C(=O)c1ccc(=O)n(C)n1 +CN(Cc1ccncn1)c1cc(-c2ccccc2)nc2ccnn12 +Cc1nnc(CN(C)C(C)c2ccc(F)c(F)c2)n1C +O=C(NC1CCCCCC1)C1CCCN1C(=O)Cc1ccccc1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)NC1C=CCCC1 +CCc1nnsc1C(=O)NCc1cccc(F)c1 +Cc1cccc(-n2c(=O)[nH]c3c(C(N)=O)nc(C)nc32)c1 +Cc1ccc2c(c1)CCCN2C(=O)c1cnccn1 +CCn1c(C)c(C(=O)NCCC(=O)N(C)C)c2cc(OC)ccc21 +COc1ccc2c(c1)nc(-c1ccccc1)c(=O)n2CCCC#N +CC1(OC(=O)c2ccc(-n3ccnn3)cc2)CCC1 +COC(=O)C(c1cc(F)c(F)c(F)c1)N(C)C(=O)c1cc[nH]c1C +CC(C)Oc1cccc2c1CCNC2Cn1cnnn1 +CCC(C)NC(=O)c1cc(-n2cnnn2)ccc1Cl +C=CCn1cc(C(=O)NCC(C)C)c2ccccc21 +CC(C)NC(=O)NC1CCN(C(=O)C2CCCC2)C1 +CSc1c(F)cc(NC(=O)CNC(C)=O)cc1F +O=C(Cn1cccc1)Nc1cc(-n2cccn2)ncn1 +CCc1ccccc1NC(=O)c1cccc(NS(C)(=O)=O)c1C +CSc1n[nH]c2ncnc(N3CCN(c4ccccc4F)CC3)c12 +C=CCOc1cccc(NC(=O)c2cc(Cl)ccn2)c1 +O=C(Nc1nnc(C2CCCCC2)o1)c1ccc(F)c(F)c1 +COc1ncccc1NCc1ccc2[nH]ccc2c1 +CCOc1ccccc1CCC(=O)Nc1ccncc1 +Cc1ccc(SCC(=O)NCC2CCCO2)cc1 +C=CCCCN(C)C(=O)Nc1ccc(Oc2ncccn2)cc1C +CCCn1nc(C(=O)Nc2ccc(C(=O)OC)cc2)ccc1=O +N#CC1(C(=O)Nc2cc(C(N)=O)ccc2Cl)CCCC1 +NC(=O)Cn1ccnc1C1CCCN(C(=O)c2cc(F)ccc2F)C1 +O=C(Nc1nc2c(s1)CCCC2)c1cnc2sccn2c1=O +O=C(CNC(=O)NCc1cscn1)NCc1ccco1 +CCc1cc2c(=O)n(C(C)Cn3cncn3)cnc2s1 +CC(C)Sc1nnc(C2CCN(C(=O)OC(C)(C)C)CC2)o1 +COc1ccc(NC(=O)c2cnc3[nH]c(C(C)=O)cc3c2)cc1 +COC(=O)c1ccc(C(=O)NC2CCSc3c(F)cccc32)cc1 +N#Cc1c(N)cc(N)nc1SCc1ccn(-c2ccccc2)n1 +O=C(c1ccccn1)N1CCCC(c2cc(=O)nc3n2CCC3)C1 +Cc1cccc(C(=O)N2CC3OCCN(C(C)C)C3C2)n1 +c1ccc2c(c1)nc1n2C(CNCc2nccs2)COC1 +COc1cc(-c2noc(-c3cn(-c4ccc(F)cc4)nn3)n2)ccn1 +CC(Oc1ccc(F)cc1)C(=O)N1CCN(c2ccccc2)CC1 +O=C1CN(C(=O)Nc2cccc(OCc3cccc(F)c3)c2)CCN1 +COc1ccc(C(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1 +CCOc1ncccc1C(=O)Nc1nnc(-c2ccco2)s1 +CCSc1nnc(SCC(=O)N2CCc3ccccc32)s1 +CCc1cc(C(=O)N2CCCc3cccc(O)c32)[nH]n1 +Cc1ccc2c(c1)C(NC(=O)Cc1ccc(Cl)cc1)CNC2 +COc1ccc(OC)c(C(=O)N2CCCC2c2cccn2C)c1 +N#CC1C=C(c2ccccc2C(F)(F)F)C=NC1=O +CCCCN(CCO)C(=O)Nc1ccc(Cl)cc1F +Fc1cccc(NCc2noc(-c3cccs3)n2)c1 +COc1ccc(SCC(=O)Nc2cccc(OC)c2)cc1 +Nc1nc2cccc(F)c2n1Cc1ccc(F)cc1 +CN(Cc1nccn1C(F)F)C(=O)c1ccc[nH]c1=O +CC(NC(=O)N1CCC(c2nnc3ccccn23)CC1)C1CCCO1 +Cn1nnnc1SCc1nc(N)nc(Nc2ccccc2)n1 +CNC(=O)NCC(=O)NCCCc1nc2c(s1)CCCC2 +CCCCc1cn(CC2CCN(C(C)=O)CC2)nn1 +Cc1ccc(S(=O)(=O)NCCCN2CCc3ccccc32)cc1 +Cc1ccc(O)c2c1C(Cc1cccc(O)c1)NCC2 +Cn1nc(C(=O)Nc2cnn(C3CCOCC3)c2)ccc1=O +COc1cccc(C(=O)CNC(=O)Cc2ccccc2)c1 +COc1ccccc1NC(=O)c1ccc(NCc2ncnn2C)cc1 +N#Cc1ccc(C2NCCc3cc(F)cc(F)c32)cc1 +Cc1ccc(S(=O)(=O)NCCc2cn3cccc(C)c3n2)cc1 +CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cccc(O)c2)CC1 +Cc1ccc(C(=O)NCCCn2ccnc2)cc1C +Cc1noc2nc(-c3ccccc3)cc(C(=O)N3CCOCC3)c12 +O=C(c1cccc(-c2cn[nH]c2)c1)N1CCc2c(nc[nH]c2=O)C1 +CC(C)n1cc(Br)cc1C(=O)Nc1ccc2c(c1)COC2 +CC(Cc1ccccc1)C(=O)N(C)c1ccccc1S(C)(=O)=O +CN(C)S(=O)(=O)c1ccc(C(=O)Nc2cccc(F)c2)cc1 +C=C(C)CN(CC)C(=O)NCC(C(C)C)N1CCOCC1 +COC(=O)CCC(=O)NCc1ccc(OC)c(C)c1 +CCn1nc(C(=O)N2CCCC(CCCOC)C2)cc1C +C#CCNC(=O)NCc1ccc(OC(F)(F)F)cc1 +Cc1cccc(CCC(=O)OCCc2cccnc2)c1 +CCC(NC(=O)N1CCN(Cc2ccon2)CC1)c1nccs1 +CCc1noc(CC)c1CC(=O)N(C)C(C)c1ccc(OC)cc1 +CC(C)NC(=O)Nc1ccc(C(=O)OC(C)C)cc1 +O=S(=O)(Oc1ccc(-n2ccnc2)cc1)c1ccccc1F +COc1ccc(CN(C(=O)c2cc3ccccc3oc2=O)C2CC2)cc1 +CNC(=O)c1ccc(CN(C)C(=O)c2cc(C)no2)cc1 +Cn1ccc(C(=O)NC2(c3ccccc3)CCCCC2)cc1=O +CC(=O)N1CCN(C(=O)C(C)CC2CCCCC2)CC1 +COc1cccc(C(=O)NC2CC(C)N(c3ccccc3)C2=O)c1F +CCN(CC1CCOC1)C(=O)CCn1nnc2ccccc2c1=O +CCOC(=O)N1CCN(CC(=O)NC(C2CC2)C2CC2)CC1 +O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1ccco1 +CCOC(=O)Cc1csc(NS(=O)(=O)c2cn(C)nc2C)n1 +O=C(Nc1cn[nH]c1)c1cccnc1OCC(F)F +CC(=O)c1ccc(NC(=O)c2cn(C)c3c(F)cccc3c2=O)cc1 +O=C(NC1CC2CC1N(C(=O)c1cccnc1)C2)c1cccs1 +Cc1nn(C)c(C)c1-c1ccnc(NCc2ccc3nonc3c2)n1 +CCOC(=O)C1CCN(c2ccc3nc(N)nn3c2C)CC1 +N#CCCN(Cc1cccnc1)C(=O)Nc1ccc2c(c1)CCCO2 +COCc1ccc(C(=O)N2CCCC(c3cc(=O)[nH]cn3)C2)s1 +O=C(CSc1nnc(NC2CCCCC2)s1)c1ccc[nH]1 +Cc1ccc(C(=O)N(C)c2ccc(O)cc2)cc1C +CCOc1ccc(OC(C)C(=O)Nc2cccc(C(=O)NC)c2)cc1 +CCN(CC(C)C)C(=O)c1ccc(Cl)c(N)c1 +O=C(NC1CCCCC1)c1nnc(Cc2c(F)cccc2Cl)o1 +Cc1csc(NC(=O)CSc2nncn2C)n1 +CCC(NS(=O)(=O)c1cc(F)c(C)cc1F)C(=O)OC +COc1cccc(CC2CN(C(=O)Nc3cccs3)CCO2)c1 +Cc1cc(NC(=O)C(C)Nc2ccc(N(C)C(C)C)c(F)c2)no1 +Nc1ccc(C(O)COc2ccc(Br)cc2Cl)cc1 +CCCCOC(=O)CC1Sc2ccc(Cl)cc2NC1=O +COc1cccc(CNc2cnc3ccccc3n2)c1OC +CCCN(CC1CC1)C(=O)c1ccc(N)cc1Cl +O=C(CCNC(=O)c1ccco1)Nc1ccccc1SC(F)F +CCN(CC)C(=O)c1cn(CCC#N)nc1-c1ccccc1 +Cc1cc(-c2nnc3sc(-c4cccc(F)c4F)nn23)n(C)n1 +Cc1ccc2c(CC(=O)OCCNC(=O)c3ccncc3)coc2c1 +CCOc1ccc(NC(=O)c2ccco2)cc1S(=O)(=O)N(C)C +CC(=O)c1c[nH]c(C(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +CC(=O)N1CCN(C(=O)C(C)Sc2ccc(F)c(F)c2)CC1 +CC(C#N)CN(C)C(=O)C1(c2ccc(Br)cc2)CC1 +CCCCN(C)C(=O)Cn1c(CO)nc2ccccc21 +Cc1ccccc1CCC(=O)N1CCN(S(N)(=O)=O)CC1 +COC(=O)C(C)CC(=O)N1CCC(NC(=O)Nc2ccccc2)CC1 +Nc1nc(N)nc(CSc2nnc(-c3ccc4c(c3)OCO4)o2)n1 +Cn1ccc(NCc2sccc2Br)n1 +CC1NC(=O)C2CN(C(=O)c3cccc4ccccc34)CCN2C1=O +O=C(CC1CCCC1)NCc1noc(-c2cccc(Cl)c2)n1 +Cc1nc(CNC(=O)CN(C)c2ccccc2)oc1C +O=C(NCC(O)c1ccc(F)cc1)c1cccc2c1OCO2 +N#Cc1ccc(CNC(=O)c2ccc(Br)c(F)c2)cc1 +CC(C)COc1ncc(CNC(=O)Cn2ccnn2)cc1Cl +O=C(Cc1cccc(F)c1F)N1CCN(Cc2cccc(O)c2)CC1 +O=C(NCc1cccnc1)c1ccc2nccnc2c1 +O=c1[nH]c(CSc2nnc(-c3ccccc3)o2)nc2ccccc12 +Cc1n[nH]c(SCc2ccccc2C#CCO)n1 +Cc1cc(C)n(CCC(=O)N2CCCC(OCc3nc(C)no3)C2)n1 +O=C(Cc1ccc[nH]1)N1CCCC(c2nc3ccccc3o2)C1 +N#CCCCSc1nnc(N2CCCC2)n1-c1ccccc1Cl +COCCNC(=O)Cc1cc(=O)oc2cc(C)ccc12 +NC(=O)NCCC(=O)Nc1cc(F)ccc1Cl +COc1cc(CNC(=O)NCc2cc3ccccc3o2)ccn1 +CNc1nnc(-c2csc(N3CCOCC3)n2)s1 +CS(=O)(=O)N1CCN(C(=O)c2ccc(-c3cc[nH]n3)cc2)CC1 +Cc1ccc(CNC(=O)c2cc3c([nH]c2=O)CCC3)cc1 +COc1ccc(C(=O)Nc2ccccc2O)cc1OC +CN(Cc1ccccc1C#N)C(CCO)c1ccccc1 +C=CCNc1nc(C(=O)OCC(=O)N2CC(C)OC(C)C2)cs1 +COc1ccc2c3c(c(=O)oc2c1)CN(C(=O)c1ccccc1C)CC3 +CCc1ccc(C(=O)N(Cc2ccsc2)Cc2ccco2)cc1 +COc1ccc(-c2n[nH]cc2C(=O)NCC(=O)N2CCCC2)cc1 +CCn1nc(C)c(CNS(=O)(=O)c2c[nH]c(C(C)C)n2)c1C +O=C(CN1C(=O)c2ccccc2S1(=O)=O)c1ccc(F)cc1F +Cc1ccc(CN(C)C(=O)c2ccc3c(c2)NC(=O)CCS3)o1 +O=C(c1c(Cl)ccc(Cl)c1Cl)N1CCCC(O)C1 +Cc1c(NCC(=O)Nc2ccc(Cl)cc2F)cccc1C(N)=O +CCC(=O)Nc1cc(C(=O)N2CCOCC2)ccc1OC +CC(=O)N1CCc2cc(NC(=O)N(C)CCC(C)O)ccc21 +O=C(Nc1ccncc1)C1CCN(c2cccc(Cl)c2)CC1 +O=C(NCCc1ccc(Cl)cc1)C1CC(=O)N(C2CCCC2)C1 +CC(CC(=O)OC1C(=O)OCC1(C)C)c1ccccc1F +CCCN(CCC)S(=O)(=O)c1cc(C)sc1C +CC(=O)Nc1ccc(C(=O)N(C)Cc2nc(C)no2)c(C)c1 +CC(=O)N1CCCN(C(=O)c2cc(F)cc(F)c2)CC1 +CC(CC#N)N(C)C(=O)Nc1cc2c(cc1Cl)OCCCO2 +Cc1ccc(NC(=O)Cn2cnnn2)c(Br)c1 +O=C(Nc1scnc1C1CC1)c1cnc(-c2cccs2)s1 +O=C(CCCc1cc(F)ccc1F)Nc1cc(C2CCOCC2)[nH]n1 +Cc1cc(C)n(CC(O)COc2ccccc2C)n1 +Cc1ccc(-n2cnnc2SCC(=O)NCc2ccco2)c(C)c1 +CCc1cccc(CC)c1NC(=O)Cc1ccc(C)nc1 +CCCCNC(=O)Cn1cnc2c(cnn2-c2ccc(C)cc2)c1=O +CCOCCCNC(=O)Nc1nnc2ccccn12 +COC(=O)C1(c2ccc(OC)cc2)CCC(=O)CC1 +CCC1CCCC(NC(=O)N2CCC3(CC2)OCCO3)C1 +CN(C)c1cccc(C(=O)N2CCC(OCc3cccnc3)CC2)c1 +O=C(NCc1nnc(C2CC2)n1C1CC1)c1cccc(F)c1Cl +COC(=O)c1sccc1S(=O)(=O)N(C)C1CCC(C)(C)CC1 +Cc1c(-c2nnc(Cc3ccccc3)o2)nnn1-c1ccc(F)cc1 +CS(=O)c1ccc(C(=O)NCCCn2ccc3ccccc32)cc1 +Cc1noc(CCCC(=O)NCc2ccnn2C)n1 +Cc1nc(NC(=O)c2ccc3c(c2)OCO3)ccc1Br +Cc1ccc(NC(=O)Cn2ccc(C(F)(F)F)n2)cc1F +CCC(C)C(NC(=O)C1CC1c1ccc(C(F)(F)F)cc1)C(N)=O +COc1cccc(OCCCNC(=O)c2cccn3cncc23)c1 +CC(C)OCCCNc1ncnc2c1cnn2-c1ccc(F)cc1 +CC(=O)c1c(O)c2c(ccc3[nH]c(=O)c(C(C)=O)c(O)c32)[nH]c1=O +Cc1cc(Br)ccc1C(=O)Nc1ccc(C#N)cn1 +Cc1csc(=O)n1CCC(=O)NC1CCOc2ccccc21 +Cc1ccsc1CNC(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CC(=O)c1sc(C)nc1-c1cnn(-c2ccccc2)c1 +O=C(NC1CC1)c1cc(C(=O)NC2CC2)cc(C(=O)NC2CC2)c1 +CCOC(=O)c1c(C)c(=O)oc2c(F)cccc12 +CCC(=O)Nc1cccc(NC(=O)C2CC(=O)N(C)C2)c1 +COC(=O)C(C)CN(C)S(=O)(=O)c1c(C)n[nH]c1C +Cc1nnc2n1CCN(c1ncnc3c1nnn3-c1ccccc1)C2 +CNC(=O)C1CCCCN1c1c(CO)c(C)nn1C +O=C(OCn1nnc2ccccc2c1=O)C1COc2ccccc2O1 +CSc1nsc(NC(=O)c2cnc(C3CCCO3)s2)n1 +Cn1c(=O)c2c(ncn2CCOC(=O)C(C)(C)C)n(C)c1=O +CN(C)C(=O)CN(C)S(=O)(=O)c1ccc2ccccc2c1 +O=C(Nc1cccn(CC(F)(F)F)c1=O)c1scnc1C1CC1 +CCC(NC(=O)N(C)C(C)c1ccncc1)C(C)C +CN(C)C(=O)CCCC(=O)Nc1ccc2c(c1)OC(C)(C)O2 +O=C(CN1CCCCC1=O)Nc1c[nH]cc(Br)c1=O +Cc1nn2c(CNC(=O)C3CCC3)c(-c3ccccc3)nc2s1 +O=C(Nc1ccccc1)c1nnc(CNC(=O)C2CC2)s1 +COCCS(=O)(=O)NCC1(c2ccc(F)cc2)CC1 +O=C(COc1ccc(F)cc1)N1CC(c2nc3ccccc3[nH]2)C1 +COc1ccccc1Cc1nnc(NC(C)=O)s1 +COCCCNS(=O)(=O)c1ccc2c(c1)CC(C)N2 +COc1ccccc1-c1n[nH]c(NC(=O)C2CC=CC2)n1 +CN(C)S(=O)(=O)c1cccc(NCC2CCOC2)c1 +CCN(CC)C(=O)CCNC(=O)N1CCC(c2ccccc2)C1 +CCOc1ccccc1OC1CCN(C(=O)C2CC=CCC2)CC1 +CC1CCC(Nc2c(-c3ccc4c(c3)OCC(=O)N4)c(=O)c2=O)CC1 +CCN(CC)S(=O)(=O)c1cccc(C(=O)NC(C)CO)c1 +CCNC(=O)C1CCN(S(=O)(=O)c2cn[nH]c2)CC1 +CC(C)c1noc(CCNS(=O)(=O)c2ccc3cn[nH]c3c2)n1 +O=C(Cc1ccccc1F)Nc1ccccc1N1CCOCC1 +O=C(Nc1ccsc1)NC1(C(=O)NCC2CC2)CCCC1 +CCOC(=O)Cc1cc(Cl)c(OC)cc1OC +O=c1[nH]ncc(NCc2ccc(F)cc2)c1Cl +CCc1n[nH]c(C2CN(C(=O)C3CC3c3cccnc3)CCO2)n1 +COc1ccc(Cc2nc(-c3cccnc3)no2)cc1OC +COC(=O)C1CCCC1C(=O)NCc1ncc[nH]1 +CC1(C(=O)OCCNc2cccnn2)CCCc2ccccc21 +O=C1CCCN1CCNc1nccc(-c2ccccn2)n1 +Cc1cnc(CN2CCCC(c3noc(C4CC4)n3)C2)o1 +Cc1ccc(CN(C)C(=O)C2COc3ccccc3C2)o1 +CCOc1ncccc1C(=O)NCc1c(CC)noc1CC +Cc1noc(C)c1CN1CCN(C(=O)CN(C)c2cnccn2)CC1 +COc1ccc(C2C(C#N)C(=O)Nc3nc4ccccc4n32)c(OC)c1 +CN(Cc1ccsc1)C(=O)Cn1c(=O)n(C)c2ccccc21 +Cc1cc(NC(=O)COc2ccccc2F)n(C)n1 +COc1ccc(Cl)cc1NC(=O)N1CCC(C(C)O)CC1 +Cc1c(C(=O)c2ccccc2)oc2ccc(F)cc12 +NC(=O)c1cccc2c1CCCN2C(=O)c1noc2c1CCCCC2 +Cc1cc(Sc2nccn2C)ccc1NC(=O)c1ccc(C#N)cn1 +CC(Sc1nc(N)nc(N)n1)C(=O)Nc1ccccc1F +Cc1ccc(C(=O)CCC(=O)OCc2ccccc2F)s1 +CC(C)n1nccc1NC(=O)c1cnn(Cc2ccccc2Cl)c1 +CCCOc1ccccc1-c1ccc(CO)c(C)n1 +N#CCCn1c(CO)cnc1SCc1cccc(Cl)c1 +CC(C)(C)c1nnc(NC(=O)N2CCCC(O)C2)s1 +COCc1ccc(C(=O)N2CCN(C(=O)CO)CC2)o1 +CC(=O)Nc1cc(C(=O)OC2CCCCC2)ccc1F +COc1ccc(CC(=O)N2CC3CC(C)OC3C2)cc1 +CC(NC(=O)c1ccco1)C(=O)N1CCC(Nc2ccccc2)CC1 +CSc1cc(C(=O)N(Cc2ccco2)CC2CCCO2)ccn1 +Cc1ccc(C(NCC(F)(F)F)C(N)=O)c(C)c1 +COc1cc(OC)c(NC(=O)c2ccc3nccnc3c2)cc1Cl +COc1cc(N2CCOC3CCC2C3Oc2ncccc2F)ncn1 +OC1Cc2ccccc2C1Nc1nccc(C(F)(F)F)n1 +CCCOCC(=O)Nc1cccn(Cc2ccccc2)c1=O +Cc1noc(NC(=O)Cn2c(=O)n(C)c3ccccc32)n1 +CCc1ccc(C2CCCCN2C(=O)CNC(=O)NC)o1 +Cc1cc2cc(CNC(=O)c3cccc(F)c3)ccc2n1C +COC(=O)C1CCC(=O)N(C)C1c1cccc(Cl)c1 +CC(=O)NC(CC(=O)N(C)Cc1ccccc1)c1ccc(C)cc1 +O=C(Cn1nc(-c2ccccc2)ccc1=O)Nc1ccccc1F +Cc1nc(-c2ncccn2)sc1C(=O)N(C)C(C)c1cccnc1 +CC(C)NC(=O)Nc1ccc(O)c(-c2nc(-c3nc[nH]n3)no2)c1 +Cc1nn(CC(C)C)c(C)c1CCC(=O)Nc1ccccc1C#N +CN(C)C(=O)Oc1ccc2c(-c3cc(F)c(F)c(F)c3)noc2c1 +CCn1cc(C(=O)OCc2nnnn2-c2ccccc2)c(C(C)C)n1 +CC(NC(=O)c1ccccc1)c1nc2ccccc2o1 +CN1C(=O)Cc2cc(C(=O)NCc3ccccc3Cl)ccc21 +Cc1cccc(NC(=O)NCCn2nc(C(F)(F)F)n(C)c2=O)c1 +Cc1ccc(CNC2CC(=O)N(C)C2c2ccc(Cl)cc2)o1 +Cn1cc(C#N)cc1C(=O)OC(CCc1ccccc1)c1nccn1C +CN1CC(C(=O)NCCCOc2ccc(F)cc2)CC1=O +Cn1c(=O)n(C)c2cc(S(=O)(=O)NC3CCCCC3)ccc21 +CCc1nnc(CN(C)c2cc(C(C)C)nc3ccnn23)o1 +OC1(Cc2ccccc2)CCN(c2ncnc3[nH]ccc23)CC1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1ccc(=O)n(C)n1 +O=C(Nc1ccc2[nH]ccc2c1)c1ccnc(F)c1 +Cc1ccccc1CN(C)S(=O)(=O)c1cccc(N)c1 +CCN(CC(O)c1ccc(C)cc1)C(=O)c1ccc(COC)o1 +COCc1nnc(NC(=O)Cc2csc(-c3ccccc3)n2)s1 +CC(C)c1ccc(CS(=O)(=O)c2ccc(O)cc2)cc1 +Cc1csc(N(C(=O)c2ccncc2F)c2ccccc2)n1 +NS(=O)(=O)CCNC(=O)c1ccccc1Cl +COC(=O)c1sc(NC(=O)CC2(O)CCCCC2)nc1C1CC1 +O=S(=O)(Cc1noc(Cc2ccccc2)n1)c1ccc(O)cc1 +CC(C(=O)OCCCc1ccncc1)N1CCc2ccccc2C1 +CCn1c2c(=O)[nH]c(=O)n(C)c2n2c(-c3ccc(Cl)cc3)nnc12 +Cc1cccc(CC(=O)N2CCC(OCc3ccc(F)cc3)CC2)c1 +Cc1nc(C)n(C2CCCN(C(=O)C3CCc4ccccc43)C2)n1 +CNC(=O)c1cccc(NC(=O)CNc2cc(C)cc(C)c2)c1 +COc1cc(OC)c(-c2cc(N)on2)c(OC)c1 +Cc1cccnc1NC(=O)CNC(=O)CC(C)(C)C +CNC(=O)c1cccnc1-c1cccc(-c2ccn[nH]2)c1 +N#Cc1ccc(-c2cccs2)nc1N1CCCCC1 +O=C(NCc1csc(-c2ccccc2)n1)c1ccoc1 +CSc1nc2ccccc2c(N2CCC(C(N)=O)CC2)c1C#N +Cc1ccoc1C(=O)Nc1c(C)noc1-c1ccccc1 +CCc1cc2nn(CC3CCCO3)c(=O)n2c(C(C)C)n1 +CCc1cc(CNCc2cc(=O)c3cc(C)ccc3[nH]2)on1 +Cc1nc(N(C)C)ncc1C(=O)N1CCCCC1c1cccc(F)c1 +Cc1ccc(Cn2c(C)cn3c4c(=O)n(C)c(=O)n(C)c4nc23)cc1 +CC(CNC(=O)CNC(=O)c1ccc(C#N)cc1)Oc1ccccc1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(C)c(Br)c1 +CCCC(=O)Nc1ccc(NC(=O)C(C)(C)C)cn1 +CNC(=O)COc1cccc(C(=O)NCC(C)O)c1 +CC1CCc2sc(C(=O)NCC(C)(C)N3CCOCC3)cc2C1 +O=C(c1cnn(-c2ncccc2Cl)c1)c1cc(F)ccc1O +CCCN(CCO)S(=O)(=O)c1cc(NC(C)=O)ccc1C +CCOC(=O)CC1NCCc2cccc(Cl)c21 +c1ccc(-n2cc(NCc3cccs3)cn2)cc1 +CSc1nc(C(C)C)nc(C)c1C(=O)N(C)CC(=O)NC1CC1 +CC1CN(C(=O)CNc2ccc(F)cc2)CC(C)O1 +COc1ccc(F)cc1S(=O)(=O)Nc1ccc(C)cc1 +CN(Cc1nc2c(s1)CCCC2)C(=O)c1scnc1C1CC1 +O=C(Cn1cncn1)Nc1ccc(N2CCc3ccccc32)cc1 +CC1=NC(CN(C)C(=O)C2Cc3ccccc3C2)N=C1 +O=C(Nc1ccc(F)c(F)c1)c1csc(-n2cccc2)n1 +c1cncc(-c2nccn2-c2cccc(-n3cnnc3)c2)c1 +C=CCN(Cc1cccnc1)c1nc(C)nc2sccc12 +CC(=O)c1ccc(S(=O)(=O)NCc2cccc(C(N)=O)c2)cc1 +Cc1cc(NC(=O)NC(c2ccccc2)c2ccccn2)n(C)n1 +Cc1ccc(C(=O)NCc2ccc(CS(N)(=O)=O)cc2)c(=O)[nH]1 +COc1ccc(-c2ncnc3nc[nH]c23)c(OC)c1OC +O=C(NCC1CN2CCCCC2CO1)c1ccc(F)c(Cl)c1 +COC(=O)C(C)CN(C)S(=O)(=O)N1CCCCC1C +CNC(=O)COC(=O)c1ccc(OCc2cscn2)cc1 +COc1cc2c(c(OC)c1)C(c1cccc(F)c1F)CC(=O)N2 +COC(=O)c1ccc(NC(=O)Cc2c(C)[nH]c(=O)[nH]c2=O)cc1 +Cc1cc(N)n(-c2nnc(-c3cccs3)c3ccccc23)n1 +CCCC(=O)Nc1ccc(C)cc1OCCOC +CCN(Cc1nc(-c2ccco2)no1)c1cccc(F)c1 +COCCn1c(C)cc(NCc2ccccc2)cc1=O +NC(=O)c1ccccc1NC(=O)Cc1noc2ccc(N)cc12 +CCCc1nc(CNc2ccccc2-n2cccn2)cs1 +Cc1cccnc1NC(=O)c1cnn2c(-c3ccccc3)ccnc12 +CCOC(C)c1nc(CSc2nncn2C(C)C)cs1 +CC(C)C(CO)NC(=O)c1ccc2nc(-n3cccc3)sc2c1 +CN(C)c1nc(N)nc(CN(C)S(=O)(=O)c2cccs2)n1 +CC(CC#N)N(C)C(=O)Nc1ccc2oc(=O)ccc2c1 +O=C(NCc1ccccc1)C1CCCN(C(=O)c2ccoc2)C1 +O=C(c1cccc(Cn2ccc(C(F)(F)F)n2)c1)N1CCCCC1 +O=C(CCn1ccc2ccccc21)NCc1ccnc(OC2CCC2)c1 +COC(=O)C1=C(C)N(CCc2c[nH]c3ccccc23)C(=O)C1 +COCc1c(C#N)nnn1-c1ccc(OC)c(OC)c1 +O=C(NCC1COC2(CCCCC2)O1)Nc1cccs1 +CCc1nc(C(=O)N2CCN(CC)CC2)nn1-c1ccccc1Cl +CCCOc1ccc(C(=O)NC2CCN(S(C)(=O)=O)CC2)cc1 +Cc1cc(=O)c(CO)nn1-c1cccc(Br)c1 +COc1ncccc1NC(=O)NCC1CN(CC(C)C)CCO1 +Cc1ccc(OCc2nnc3c(N)c(Cl)ccn23)cc1 +O=C(COC(=O)Cc1cccs1)NCc1ccccc1Cl +C=C(C)COc1ccc(C(=O)N2CCN(CCC#N)CC2)cc1 +Cn1cnnc1CNC(=O)CCCNC(=O)c1ccc(F)cc1 +O=C1CCCCN1CC1CCN(C(=O)C2CC2)CC1 +Cc1cc(SCCC(=O)Nc2ccc(Cl)cc2)ncn1 +COc1ccc(C(=O)CSc2nnc3ccccn23)cc1 +CC(OCc1ccccc1)C(=O)N1CCOc2ccc(F)cc21 +CCC(CC)N(CCOC)C(=O)Nc1ccc(F)c(C#N)c1 +Cc1cc(NC(=O)CN2CCN(CCO)CC2)n(C(C)(C)C)n1 +Cc1c(NC(=O)C2(c3cccc(F)c3)CCC2)cccc1C(N)=O +Cc1ccc2c(c1)C(=O)C(NC(=O)c1ccc(F)cc1)CS2 +Cc1nc(C)n(C2CCCN(C(=O)c3ccc(C#N)c(C)n3)C2)n1 +CC(NS(=O)(=O)c1cnn(-c2ccccc2F)c1)c1ccncc1 +CCc1c(N)c(=O)n(-c2ccccc2Br)n1C +CCOC(=O)C(C)NC(=O)c1ccc(N)cc1Cl +COc1cc(OC)c2c(C)c(CC(=O)N3CCCC3)c(=O)oc2c1 +Cn1ccnc1SCC(=O)Nc1cc(Cl)ccc1F +O=C(CCc1nc(-c2ccco2)no1)Nc1ccccc1F +O=C(N1CCCC1)N1CCC2(CC(=O)N(c3ccccn3)C2)C1 +Cc1ccc(OCCNS(=O)(=O)c2cnn(C)c2)cc1 +O=C1CCN(C(=O)COc2cccc(Br)c2)CC1 +O=C(CCCC1CCCCC1)N1CCN(c2ncccn2)CC1 +C#CCOc1ccc(CCNC(=O)c2ccc(OC)nn2)cc1 +O=C(COc1ccc(F)cc1)NCc1ccc2c(c1)OCCO2 +CN(CCC#N)C(=O)Nc1ccc(OCc2noc(C3CC3)n2)cc1 +O=C(c1cnc2n(c1=O)CCS2)N1CCN(c2nccs2)CC1 +O=C(Nc1cccc2ccccc12)c1ccc(=O)oc1 +OCCNc1ncnc2c1ncn2Cc1ccccc1 +CCOc1ncc(C(=O)NCCc2csc(C)n2)cc1Cl +COc1ccc(C)cc1CN(C)C(=O)c1ccc(-n2cccn2)nc1 +CN(Cc1cccs1)C(=O)c1nn(C)c2ccc(Cl)cc2c1=O +CN(C)C(=O)c1nc(-c2ccccc2)oc1C1CC1 +O=C(NCc1cccc(O)c1)c1cc2c(s1)CCCC2 +CCC(C)NC(=O)Cc1csc(-c2cccs2)n1 +O=C(c1cn2cccnc2n1)N1CCCC1c1nc2ccccc2s1 +O=C(CCSc1ccccc1)Nc1cccc2cccnc12 +Cc1nc2ncccn2c1-c1csc(Nc2ccccn2)n1 +COc1ccc(-n2ccc(CNC(=O)c3cc(Cl)c[nH]3)n2)cc1 +CC(=O)NCc1ccc(C(=O)OCCc2scnc2C)s1 +Oc1cccc(-c2noc(-c3ccc(Br)cn3)n2)c1 +O=C(CCCOc1ccc2c(c1)CCC(=O)N2)NCc1ccncc1 +COc1ccc(C(=O)Nc2cc(F)ccc2F)cc1N +CCCCN(C)C(=O)Nc1cc(OC)c(OC)c(OC)c1 +O=C(CC1CC1)NCc1noc(-c2ccc(F)cc2)n1 +Cc1ncc(CNC(=O)c2cc(C)n(C3CC3)c2C)s1 +CCN(CC)C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1 +COc1cc(=O)n(-c2ccc(C)cc2)nc1C(=O)N1CCCCCC1 +C=CCOC(=O)c1cccc(C(=O)N(C)CC(C)C)n1 +Nc1ccc2oc(-c3ccc4c(c3)CCC4)nc2c1 +N#Cc1cccc(NC(=O)Cn2cnc3cc4c(cc32)OCCO4)c1 +C#CC(C)OC(=O)C1CC(=O)N(Cc2ccccn2)C1 +O=C(Cn1c(=O)cnc2ccccc21)c1ccc2c(c1)OCO2 +Cc1nn(-c2ccccc2)c(C)c1C(=O)N1CCC(C)CC1 +COc1cccc(NC(=O)NCCc2ccsc2)c1OC +CC(C)c1nc(CNc2cccc(-c3nnnn3C3CC3)c2)no1 +O=C(Cc1cn2ccsc2n1)N1CCCC1COc1ccccc1 +CCOC(=O)c1cc(N)n(-c2cc(Cl)ccc2Cl)n1 +O=C(Nc1cccnc1)C1(c2ccc(F)cc2)CC1 +O=C(CNC(=O)c1ccc(Cl)cc1Cl)NCC1CCC1 +CNS(=O)(=O)c1ccc(CCC(=O)N(C(C)C)C2CCC2)cc1 +Cn1c(COc2cc(Cl)ccc2Cl)nnc1SCC(N)=O +O=S(=O)(NCc1nnc2ccccn12)N1CCOCC1 +CCC1CCCCN1C(=O)CNc1ccccc1C +CC=Cc1ccc(OC(=O)c2cnc(C3CCCO3)s2)c(OC)c1 +CSc1ccc(-c2noc(-c3ccc[nH]3)n2)cc1 +CCOCC1CN(C(=O)c2ccncc2)Cc2nn(C)cc21 +COc1ccc(-c2ncc3c(n2)CCCC3)c(N)c1 +O=C(COc1ccc2ccc(=O)oc2c1)NCC(F)(F)F +O=C(Nc1nc2ccccc2s1)Nn1cnc2ccccc21 +Cc1cc(C)n(CCC(=O)Nc2cc(N)ccc2C)n1 +CCN(CCn1cccn1)C(=O)c1cnc(-c2cccnc2)nc1 +Cn1nc(-c2csc(S(=O)(=O)N3CCCCC3)c2)ccc1=O +CCc1nc(CSc2ccccc2)sc1CO +Cc1nn(C)cc1NC(=O)N1CCCC1c1ccc(F)cc1 +CCC1CN(C(=O)NCCC(=O)OC)c2ccccc2S1 +CC(Oc1ccc(F)c(F)c1)C(=O)N(C)C1(C#N)CCC1 +Cc1cc(Sc2ccccc2)ccc1NC(=O)CN(C)C(N)=O +CC(C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C)c1ccccc1F +Cn1cc(CCC(=O)NCCc2cccc3ccccc23)cn1 +Cc1ccc2c(CC(=O)NCCCN3CCOCC3)coc2c1 +COC(=O)c1ccccc1C(=O)NCCc1cc(C)no1 +COCCCNC(=O)Nc1ccc(C)c(NC(C)=O)c1 +CC(NC(=O)CCC1Cc2ccccc2NC1=O)c1ccccn1 +COc1cc(NC(=O)c2ccc(C)cc2)ccc1OC(F)F +CN(C)C(=O)Cn1cc2c(n1)C(CNCc1ccoc1)OCC2 +CC1(C)OC(=O)N(CC(=O)Nc2ccc(F)cc2)C1(C)O +Cc1cc(-c2ccccc2)cn(CCCC#N)c1=O +CC(NC(=O)NC1c2ccccc2CC1O)c1nncn1C +Cn1nc(NC(=O)c2cccs2)c2c1NC(=O)CC2c1ccco1 +CCC(C)Nc1nc(-c2cnc(N(C)C)s2)cs1 +COc1ccc(C(=O)Nc2ccc(C)cc2F)cc1 +Cc1cc(C(=O)N2CCCCC2)c(C)c(F)c1F +CCc1cc(NC(CC)COC)n2nc(C)c(C)c2n1 +Cc1cc(NCC(=O)N(C)C2CC2)ccc1Br +CCOc1cc(CNc2cnccc2C)ccc1O +O=C(NC(CN1CCOCC1)c1ccccc1)c1ccccc1Cl +Cc1[nH]c2c(-c3ccccc3Br)cnn2c(=O)c1C +CC(C#N)Sc1nnc(C2CC2)n1Cc1ccccc1 +CCC(NC(=O)Cn1nnc(-c2ccccc2)n1)c1ccc(C)cc1 +CCn1ncc2c(C(F)(F)F)cc(C3CC3)nc21 +CCN(Cc1cccc(F)c1)C(=O)CCC(=O)Nc1nccs1 +CC1CCCN(C(=O)CSc2nnc(-c3ccccc3F)n2N)C1 +Cc1ccc(C)c(NC(=O)c2cccc(N(C)S(C)(=O)=O)c2C)c1 +CCOCCOCC(=O)Nc1ccc(C)c(F)c1 +CC(=O)N1CCC(C(=O)Oc2ccc(Br)cc2F)CC1 +Cc1nc(CNC(=O)Nc2cnn(CC(N)=O)c2)cs1 +Cc1ccc(-n2ncc(C(=O)Nc3cccc(C)n3)c2C(C)C)cc1 +NC(=O)COc1ccc(C(=O)OC2CCCCC2)cc1N +N#Cc1cccc(C(=O)OCC(=O)c2ccc3c(c2)OCO3)c1 +O=S(=O)(NC(C1CC1)C1CC1)c1ccccc1 +COc1ccc(OCCCNC(=O)c2cnn[nH]2)cc1 +CCOC(=O)c1cc(C(=O)Nc2ccccc2Cl)c(=O)[nH]c1C +NC(=O)c1ccc(C2CN(S(=O)(=O)c3ccccc3)CCO2)nc1 +CCC1Nc2cc(C)ccc2N(CCCC#N)C1=O +CCOc1cc(C#N)ccc1OC(=O)c1cnccn1 +O=C(NCc1ccncc1)c1cc2cccc3c2n(c1=O)CCC3 +Cc1nn(C)c(C)c1C(=O)OC(C)CN1CCOCC1 +CCC(=O)Nc1ccc(NC(=O)C2CCCCC2)cn1 +Cc1cc(OCC(=O)NCC(C)(C)N2CCOCC2)ccc1C(C)C +COc1ccccc1CNC(=O)N1CCCC(CO)C1 +Cc1noc(-c2c(C)sc(C)c2S(=O)(=O)NC(C)(C)C)c1C +Cc1ccc(C)c(C2CN(S(=O)(=O)CCCC#N)C(C)CO2)c1 +CCOc1ccnc(N2CCN(C(=O)CCc3cscn3)CC2)n1 +C=CCn1c(SC(C)C(C)=O)nnc1-c1ccc(OC)cc1 +Cc1ccc(NC(=O)CSc2nc3c(cc2C#N)CCC3)cc1 +COC(=O)CN(C(=O)Cc1ccc(-n2cnnn2)cc1)C(C)C +CC(=O)NCCNC(=O)c1cc2ccccc2cc1NC(=O)C1CC1 +COc1ccc(C(C)NC(=O)C2CC(=O)Nc3ccccc32)cc1F +CCn1nc(C(=O)N(C)CC2CCN(c3ccccc3)C2)cc1C +NC(=O)c1cncc(Oc2nc(C(F)F)nc3ccccc23)c1 +Cc1cc(C(=O)N2CCCC2)ccc1NCc1nnc(C(C)(C)C)o1 +COC(=O)c1ccc(C(=O)Nc2ccc(N)cc2N)cc1 +CSc1ccc(OC(C)C(=O)Nc2cc(C)n[nH]2)cc1 +CCC1(O)CCN(C(=O)c2ccc(-c3cccc(F)c3)cc2)CC1O +CC(=O)N1CCC(Cc2cc(Nc3ncccn3)ncn2)CC1 +COc1ccc(S(=O)(=O)Nc2ccc3c(c2)CCC(=O)N3)cc1 +CCOC(=O)c1cc(OC)n(-c2ccc(C)cc2)n1 +CNc1ccc(Oc2ncccc2C(F)(F)F)cc1 +COc1ccc(S(=O)(=O)N2CCC(Oc3cccnc3)CC2)cc1 +COc1ccc(-c2nc(-c3ccc(CNC(C)=O)s3)no2)c(C)c1 +COc1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1OC +CC(C)CNC(=O)N1CCCC(C(=O)NCCOc2cccnc2)C1 +CC(O)CNC(=O)c1nc(Cc2c(Cl)cccc2Cl)no1 +CCNC(=O)NC1CC(=O)N(c2cccc(F)c2)C1 +Nc1nc(-c2ccccc2)ccc1C(=O)Nc1cccnc1 +COC(=O)C(NC(=O)COc1c(C)cccc1C)C(C)C +COC(=O)c1ccc(CN(C(C)C)C(F)(F)F)cc1 +CC(C)C(=O)Nc1ccc(OCc2cccnc2)c(Cl)c1 +COCCCNC(=O)NC(C)c1nnc2ccccn12 +Cc1ccc(S(=O)(=O)Oc2cc(C(=O)N(C)C)ccc2C)s1 +CCNC(=O)c1cccc(NC(=O)N2CCCC(CC)C2)c1 +COc1cc(F)ccc1S(=O)(=O)n1cnc2cc(C)c(C)cc21 +CCn1c(C)cc2cc(NS(=O)(=O)c3cn(C)nc3C)ccc21 +CCOc1cc(N)ccc1NC(=O)c1cc2ccccc2o1 +Cc1cccc2c(=O)n(CC(=O)NCc3cscn3)cnc12 +CC(=O)N(CCc1cccc(C)c1)Cc1cc2cc(C)ccc2[nH]c1=O +Cc1ccccc1CCNC(=O)N1CCC(C(N)=O)CC1 +CN(CCC#N)C(=O)Cc1cc(Cl)ccc1Cl +Cc1ccc(NC(=O)c2nccc3c(N)cc(F)cc23)cc1 +Cc1n[nH]c(-c2cccc(CNC(=O)CCc3ccccc3)c2)n1 +O=C(NC1CCC(O)CC1)C1(c2cccc(F)c2)CCCC1 +COC(=O)C1(C)CCN(C(=O)Nc2c(C(C)C)cccc2C(C)C)C1 +O=C(NCc1cscn1)N1CCN(c2ncccn2)CC1 +O=C(NCCCN1CCOCC1)Nc1ccc(F)cc1 +O=C(Cc1csc(Nc2ccccn2)n1)NCC1CCCO1 +CCOC(=O)CCc1c(C(F)(F)F)n[nH]c1O +O=C(NCCN1CCNC1=O)c1ccc2cccc(F)c2n1 +COCCC1(CO)CCCN(c2nc(C)cc(C)n2)C1 +Cc1cccc(C)c1OC(C)CC(=O)N1CCNCC1 +Cn1cnc2cc(OC(=O)Nc3cccs3)ccc21 +Cc1ccc(C(=O)N2CCc3c(N)cccc32)cc1C +COC1CCN(c2nnc(C)s2)CC1Cc1cccc(C)c1 +N#CCCSc1nnc(-c2ccncc2)n1-c1ccccc1 +CCCC1Nc2ccccc2N(C(C)C(=O)OC)C1=O +Cc1noc(-c2ccc(N3C4CCC3CC(=O)NC4)nc2)n1 +COc1ccc(NC(=O)c2ccc(-n3cnnn3)cc2)cc1 +COc1cccc(OCC(=O)N2CCCc3ccc(N)cc32)c1 +CCNC(=O)c1ccc(C)c(NC(=O)NCC(C)CC(C)O)c1 +Cc1cnc(Cn2ccnc2-c2ccc(-c3ccccn3)cc2)cn1 +CCn1ccc(NC(=O)c2cc(NC(=O)C3CCCC3)n(C)n2)n1 +CC(C)CC(NS(C)(=O)=O)C(=O)N1CCC(CO)C1 +O=C1Nc2ccc(S(=O)(=O)N3CCCCC3)cc2C1=C1CCCC1 +Cc1cc(NC(=O)Cn2cc(C(F)(F)F)cc(Cl)c2=O)on1 +Cc1cc2c(cc1F)C(=O)NC1(CCOCC1)N2 +Cn1cnnc1-c1ccnc(NCc2ccccc2Cl)c1 +Cc1cccc(CCc2nc3scc(N)n3n2)c1 +O=C(COc1ccc(Br)cc1Cl)NCC(F)(F)F +Cc1cc(C)c(CNc2cccc(-n3nnnc3C)c2)cc1C +O=C(NCc1ncc(-c2ccccc2)[nH]1)c1cc2ccccc2oc1=O +CC(Cn1cccn1)NC(=O)c1cc(C2CC2)nn1-c1ccccc1 +CCc1cc(NC(=O)NCC(Cc2ccc(F)cc2)C(N)=O)n(C)n1 +CC(C)CCNC(=O)C1CCN(C(=O)c2cccc(F)c2)CC1 +O=C1OCCN1Cc1cc(C2CCCCC2)no1 +CC(=O)N1CCC(C(=O)NCc2cccc(Cl)c2)CC1 +Cc1csc(C2(NC(=O)Cc3n[nH]c4ccccc34)CCCC2)n1 +CCc1ccsc1CNC(=O)NC1CCOC(C2CC2)C1 +O=C(CSc1cn[nH]n1)NC1C2CC3CC(C2)CC1C3 +CCc1sc(C(=O)OCn2nnc3ccccc3c2=O)cc1C +Nc1oc2c(c1C(=O)c1cccc(C(F)(F)F)c1)CCC2 +COc1ccc(OC)c(CCNC(=O)C(C)c2c(C)n[nH]c2C)c1 +CC(O)CNC(=O)c1cccc(S(=O)(=O)N2CCCCC2C)c1 +CCc1n[nH]c(C2CN(C(=O)c3cnc(C)s3)CCO2)n1 +O=C(Cc1ccc(F)cc1)N1CCN(C(=O)C2CCCC2)CC1 +CN(Cc1nc2ccccc2s1)C(=O)c1cc(C(N)=O)cs1 +COc1ccnc(NC(=O)c2cc(N3CCCC3=O)ccc2F)c1 +N#CC(C(=O)Nc1ccccc1)S(=O)(=O)c1ccccc1 +Cc1ccc(C(C)NC(=O)c2scnc2C)s1 +COc1ccc(NC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1OC +COCCn1cc(NC(=O)c2cnn(-c3ccc(Cl)cc3)c2)cn1 +COc1ccc(CN2C(C)COCC2C)cc1Br +CCOC(=O)c1ccc(NC(=O)c2ccc(S(C)=O)cc2)cc1 +COC(=O)CCS(=O)(=O)Nc1ccc(Br)cc1N +CC(=O)Nc1cc2c(cc1Sc1ccccc1)n(C)c(=O)n2C +Cc1occc1COC(=O)c1nnn(-c2ccc3ncccc3c2)c1C +O=c1cc(N2CCOCC2)c(-c2ccccc2)n[nH]1 +CCOC(=O)c1sc(NC(=O)c2cc(C)n(CC)n2)c(C#N)c1C +CC(C)S(=O)(=O)N1CCN(CC(O)C2CC2)CC1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1cccc(-n2cccc2)c1 +CNC(=O)CC(C)N(C)Cc1ccc(C(F)(F)F)nc1 +CC(=O)Nc1nc(-c2cccc(Cl)c2)ns1 +CC(=O)N1Cc2ccccc2CC1C(=O)Nc1cccc(Cl)c1C +COc1cc(OC)c(C(=O)C2CCC2)c(OC)c1 +Cc1nnc2c(NC3CCCCC3)nc3ccccc3n12 +CCOc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1Cl +CC(C#N)CN(C)C(=O)c1cc(C(C)C)n(C(C)(C)C)n1 +c1ccc(Cc2nnc(SCc3nnc(C4CC4)o3)o2)cc1 +O=C(NC(CO)Cc1ccccc1)c1cc(=O)c2ccccc2o1 +N#Cc1ccccc1NC(=O)c1ccc(OCC2CC2)cc1 +CCN(C(=O)COc1cccc(C(C)=O)c1)c1cccc(F)c1 +Cc1cc(N)nc(SCCOc2cccc(C#N)c2)n1 +CNC(=O)CN1CCN(C(=O)Cc2ccc(Cl)cc2Cl)CC1 +CC(Sc1ncc2ccccn12)C(=O)Nc1ccccc1C#N +COc1cc(NC(=O)c2ccc(-n3cncn3)nc2)cc(OC)c1 +CNC(=O)C1CCCCN1C(=O)CCCNC(=O)c1ccc(F)cc1 +Cc1nc2cc(C(=O)NCc3nccn3C)ccc2n1C +COc1cc(NC(=O)c2n[nH]c3ccc(C)cc23)cc(OC)c1OC +COC1CCC2C1OCCN2Cc1ccsc1 +Cc1ncsc1CNC(=O)N1CCc2ccc(Cl)cc2C1 +O=C(NCC1CCOC1)c1cccnc1OCC(F)(F)F +CCn1c(C(=O)NCC(C)(C)C(N)=O)cc2ccccc21 +CCOc1ncccc1C(=O)N(Cc1ccccc1OC)C1CC1 +CC(C)(CNC(=O)c1ccc2c(c1)OCC(=O)N2)N1CCOCC1 +COc1ccc2c(c1)CCCC2CC(=O)Nc1nc(C(C)=O)cs1 +COc1ccc(C)cc1NC(=O)COc1ccccc1NC(C)=O +Cn1cccc1C(=O)NCCCSc1ccccc1 +COc1ccc(C(=O)NCCNC(=O)NCc2cnc(C)s2)cc1 +Cn1nccc1CNC(=O)Nc1ccccc1OCCC(N)=O +CCCC(=O)NCC(=O)Nc1ccc(Cl)cc1 +CC1CCCCC1NC(=O)Nc1cn(C)c(=O)c2ccccc12 +Cc1cc(C(=O)Oc2ccc(F)cc2)c2c(C)nn(C)c2n1 +COCc1cc(C(=O)NCc2ccnc(OC(C)(C)C)c2)ccc1F +NC(=O)C1CCCN(S(=O)(=O)c2ccc(N)cc2)C1 +Cc1ccc(C(=O)NCCNC(=O)Cc2ccccc2C)cc1F +O=C(COC(=O)c1ccc(F)cc1Cl)NCCc1ccccc1 +COc1ccc(CCOc2ccc(CO)cc2)cc1OC +CC(C)c1ccc(C(=O)Cn2cnc(C3CCC3)cc2=O)cc1 +O=C(Cc1cccs1)Nc1cccc2[nH]c(C(F)(F)F)nc12 +CCC1CCCC(NC(=O)NC(C)C(=O)NCc2ccccc2)C1 +Cc1noc(C)c1S(=O)(=O)N1CCC(CC(=O)NC2CC2)CC1 +COCc1ccc(C(=O)NCCc2nnc3n2CCCCC3)o1 +COCCn1c(-c2ccc(Cl)cc2)ccc(N)c1=O +O=C(c1ccc(OCc2cscn2)cc1)N1CCCC1 +Cc1ccc(OCC(=O)Nc2cc3c(cc2C)n(C)c(=O)n3C)cc1 +CCCOc1cc(F)ccc1NC(=O)CSc1ccncc1 +COC(=O)c1cccc(OC)c1OC(=O)Cc1cccs1 +CCCNC(=O)CCNC(=O)Nc1ccccc1CC +CC(=O)N(CCc1ccccc1)CC(=O)N(C)c1cc(F)ccc1F +O=C(Nc1c(F)cccc1F)NC(CCCO)c1ccccc1 +COc1cccc(NS(=O)(=O)c2ccc3c(c2)CCC3)c1 +Cc1cc(C(F)(F)F)nn1CCCNC(=O)c1c(N)cnn1C +CC(=O)N1CCCN(C(=O)c2ccc(C)[nH]c2=O)CC1 +NC(=O)Cn1cc(NC(=O)N2CCC(CO)CC2)cn1 +CC(=O)Nc1ccc(C(=O)c2ccc(Cl)cc2)c(O)c1 +CCN(CCO)C(=O)Cn1cccc(C(F)(F)F)c1=O +CC(C)n1cnnc1SCC(=O)Nc1ccc(Cl)c(Cl)c1 +CC(C)n1cc(C(=O)NCc2cccc(N3CCCC3)c2)cn1 +CN(C)C(=O)N1CCN(CC(O)COCc2cccs2)CC1 +N#Cc1cccc(Cn2cnc3ccsc3c2=O)c1 +Cc1cc(C)n(-c2ccc(Cl)c(C(=O)Nc3cnn(C)c3)n2)n1 +Cc1cc(NC(=O)C2CC2)n(-c2ccccc2C(F)(F)F)n1 +COc1ccc(OC)c(CCNC(=O)C(N)c2ccccc2)c1 +COc1cc(OC)c(NC(=O)NCc2ccccc2CO)cc1F +CC(Oc1ccc(F)cc1F)C(=O)Nc1ccccc1C(N)=O +COc1ccccc1-c1csc(NC(=O)c2sc(C)nc2C)n1 +O=C(NCCO)c1cc2sccc2n1Cc1cccc(F)c1 +CCC(C)(C)C(=O)N1CCC(C(=O)N2CCc3ccccc3C2)CC1 +CC1CN(C(=O)Cc2cccs2)C(C)(C)CO1 +COc1cc(C)c(NC(=O)C(NC(C)=O)C(C)C)cc1OC +CCCNC(=O)CCNC(=O)Nc1ccc(-c2ccccc2)cc1 +CC(C)OCCC(=O)N(C)c1ccc(F)c(F)c1 +COc1ccccc1N1CCN(C(=O)c2ccccc2SC)CC1 +NC(=O)c1ccccc1OCC#CCNC(=O)c1ccc(=O)[nH]c1 +CCC(COC)NC(=O)c1ccc(-n2cccn2)c(F)c1 +NC(=O)C1CCN(C(=O)C(Sc2ccccc2)c2ccccc2)C1 +COc1ccc(S(=O)(=O)NCc2cccnc2)cc1OC +CCC(C)NC(=O)Cn1c(CO)nc2cc(OC)ccc21 +CC1(c2cc(F)c(Cl)cc2Cl)COCCN1 +CCc1nn2c(CNC(=O)c3ccc(OC)nc3)c(C)nc2s1 +O=C(Nc1ccc(-c2nccs2)cc1)Nc1cn[nH]c1 +COC(=O)CCN(C)C(=O)C1CCCN(C(N)=O)C1 +CCc1nc(NCC(C)C)c(C#N)c2c1COC(C)(C)C2 +COc1ccc(C2NC(=O)c3c(sc4c3CCCC4)N2)cc1 +Cc1ccc(-c2nc3n(n2)C(C(=O)Nc2ccccc2)CC(=O)N3)cc1 +CC1CN(Cc2sccc2Br)CCCO1 +COC(=O)c1ccc(Cn2c(=O)oc3cc(Cl)ccc32)cc1F +CCOc1ncccc1C(=O)OCc1nc(-c2ccsc2)no1 +Cc1cccc2nc(C(=O)Nc3cccc(Oc4cccnn4)c3)cn12 +Cc1ccn2cc(-c3ccc(NC(=O)Cc4ccccc4)cc3)nc2n1 +NC(=O)c1ccc(CSc2nnc(N3CCOCC3)s2)cc1 +O=C1CC(C(=O)N2CCCC2c2ccncc2)CN1C1CC1 +Nc1cc(N2CCOCC2)nn1-c1ccc(F)c(Cl)c1 +Cc1ccc(CCC(=O)Nc2cccc(CO)c2)cc1 +Cc1nc(-c2ccc(C(=O)N3CCOCC3)cc2)no1 +COc1ccccc1C#CCNC(=O)Nc1cccc(OC)c1OC +Nc1ccnn1-c1ccc(Cl)c(C(F)(F)F)c1 +Cc1ccc(NC(=O)c2ccc3c(=O)n(C)c(=O)n(C)c3n2)cc1 +Cc1ccc(OC2CCN(C(=O)C3(C)CCC3)CC2)nc1 +CCCS(=O)(=O)NCC(c1ccc(Cl)cc1)N1CCOCC1 +CCC1(CCC(=O)N2CCc3sccc3C2)CCC(=O)N1 +CCCCCNC(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +COc1ccc(NC(=O)C(C)NC(=O)OC(C)(C)C)cn1 +CC(C)(C)c1ccc(S(=O)(=O)NCC(N)=O)cc1 +CCCOc1cc(C)c(C)cc1S(=O)(=O)Nc1ccccn1 +CCCNC(=O)C(C)Sc1nccn1-c1ccccc1 +CC(C)C(=O)NCC1CCN(c2ccc(F)c(F)c2)C1 +Cc1ccnc(NC(=O)c2ccc(NC(=O)c3cccs3)cc2)c1 +C=CCCC1NCCc2c(OC)ccc(Br)c21 +CCc1nnc(NC(=O)c2ccc(-n3cnc4ccccc43)cc2)s1 +CCn1nc(C(=O)Nc2nc3c(C)c(C)ccc3s2)cc1C +NC(=O)CC1CCN(C(=O)Cn2ccc3ccc(Cl)cc32)CC1 +COc1ccc(CN(C)C(=O)c2ccc(N)cc2)cc1 +Cc1csc(N2CCC(C(=O)NCCNC(=O)C3CC3)CC2)n1 +Cc1c(C(=O)N2CCCC2C(=O)NC(C)C)nc2c(Cl)cccn12 +CSc1ccc(C(=O)Nc2[nH]nc(-c3ccncc3)c2C)o1 +COC(=O)CCC(=O)N(c1ccccc1)c1ccccc1 +CCCNC(=O)c1ccc(NC(=O)NC(C)CO)cc1Cl +COCC(NC(=O)Nc1nn(-c2ccccc2Cl)cc1C)C1CC1 +CC(CNC(=O)NC1(C)Cc2ccccc2C1)Cn1cccn1 +Cc1ccc(C(=O)CC2(O)C(=O)N(C(C)C)c3ccccc32)o1 +Cc1ccc(NC(=O)CNc2ccc(C(=O)NC(C)C)cc2)cc1 +COc1cc(C)c(C(O)CCC(=O)N2CCCCC2)cc1C +NC(c1ccc(Br)c(Cl)c1)C(F)(F)F +COC(=O)c1ccccc1OS(=O)(=O)c1ccccc1 +CC(C)c1ncc(N(C)CC(C)(C)C)c(CO)n1 +CCC1(C)OC(=O)N(CCC(=O)Nc2cccc(F)c2)C1(C)O +CCOc1cc(CNC(=O)c2c(F)ccc(F)c2OC)ccn1 +Cc1ccc(C)c(NC(=O)Cc2ccc(S(C)(=O)=O)cc2)c1 +CC(NC(=O)c1ccc2c(c1)OCCCO2)C(=O)N(C)C +O=C(Nc1cc(N2CCCS2(=O)=O)ccc1F)C1CC1 +CCC(C)(C)NC(=O)c1c(OC)cccc1OC +Cn1nnc2cc(C(=O)N3CCCC3CC(=O)c3ccccc3)ccc21 +CCCC(=O)NCC(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +Cn1c2ccccc2c2nnc(SCC(=O)N3CCCCC3)nc21 +O=c1[nH]ncc(N2CCCC(c3nc4ccccc4[nH]3)C2)c1Cl +Cc1nc(NC(=O)CNC(=O)COc2ccccc2)sc1C +COC1CCCN(C(=O)CCN2C(=O)C(C)Oc3ccccc32)C1 +Cc1cc(NC(=O)c2ccc3ccccc3c2)ccc1C(=O)N(C)C +COc1cc(CNC(=O)Cc2cc(Cl)c3c(c2)OCCO3)ccn1 +CC(C)S(=O)(=O)N(C)Cc1ccc2c(c1)OCO2 +CCc1cc(=O)[nH]c2cc(NC(=O)c3cnccn3)ccc12 +CC1Cc2cc(S(N)(=O)=O)ccc2N1Cc1cccc(C#N)c1 +O=C(CC1(O)CCCCC1)N(Cc1cccs1)CC1CCCO1 +Cc1nc(C)c(C(=O)OC(C)C(=O)Nc2nc(C)c(C)s2)s1 +COc1ccccc1NC(=O)c1ccc2nc(C)c(C)nc2c1 +COc1c(Cl)cccc1NC(=O)N1CC2C3CCC(O3)C2C1 +CN(C)c1ncncc1NC(=O)NC(C)(C)c1nccs1 +Cc1cccc(Cl)c1NC(=O)CN1CCOCC1C1CC1 +COc1cc(NCC2CC3C=CC2C3)ccc1NC(C)=O +CN(CC(=O)NCc1ccccc1)S(=O)(=O)c1ccccc1F +Cc1ccc(SCCC(=O)Nc2ccc(C(N)=O)cc2)cc1C +CCCCCC(=O)Nc1nc2nc(C)cc(C)n2n1 +FC(F)(F)Oc1ccc2c(c1)C(CC1CC1)NCC2 +COC(=O)c1cccc(-c2ccc3nc(C)[nH]c(=O)c3c2)c1 +COc1ccc(OC)c(CN(C)Cc2cccnc2C)c1 +CN(CCNC(=O)Cc1ccc2c(c1)CCO2)C(=O)OC(C)(C)C +CN(C(=O)C1CC1)c1ccccc1C(=O)NCC(O)c1cccs1 +Cc1nn2c(=O)c3c(cc(C)n3Cc3ccccc3F)nc2s1 +CCn1c(N2CCN(CC(N)=O)CC2)nc2c1c(=O)[nH]c(=O)n2C +O=C(NCC#Cc1ccccc1)Nc1cccnc1 +CN(C(=O)c1ccc(CN2CCOCC2)cc1)c1ccccc1 +COCCCCSc1nnc(C2CCOCC2)n1N +O=C(CCNc1ncccn1)N1CCOC(c2ccc(Cl)cc2)C1 +Cc1cccc(OCC(=O)NCc2ccccc2)c1 +CC(C)C(O)CC(=O)NC(c1ccc(F)c(F)c1)c1ncon1 +Cc1oc2ncn(C)c(=O)c2c1C(=O)N(C)c1ccccc1 +CCn1cc(C#N)c(=O)n(CC(=O)c2ccc3c(c2)CCO3)c1=O +Cn1cc(CCC(=O)N2CCc3ccc(Cl)cc3C2)cn1 +COc1ccc(CC(=O)Nc2ccc(S(N)(=O)=O)cc2F)cc1 +Cc1cnc2c(c1)nc(-c1ccc(F)cc1)n2CCC#N +O=C(OCc1nnc(-c2ccccc2)o1)c1cccc2c1OCCO2 +O=C(Cn1cccn1)N1CCN(S(=O)(=O)C2CC2)CC1 +CNc1snc(C)c1C(=O)N(C)Cc1ccsc1 +COC(=O)CCc1nnc(NC(=O)NC(C)c2ccc(C)o2)s1 +COc1ccc(C(=O)N2CCOCC2)c(OC)c1 +Cc1cccc(=O)n1CCC(=O)N1CCOCC(O)C1 +CCOc1ccc(F)c(C(=O)N(C)Cc2cc(Cl)cn2C)c1F +O=C(OCC1CCOCC1)c1ncn(-c2ccccc2)n1 +O=C(NC1CCCC1)c1cc(-c2ccccc2O)no1 +Cc1cc(C(=O)N2CC(C)Sc3ccccc32)c(C)o1 +Fc1ccc(-n2nc(-c3cccs3)c3c2CCNC3)c(F)c1 +CC(C)C(=O)NCCNC(=O)Cc1ccc(N2CCCC2=O)cc1 +O=C(CCC(=O)N1CCOc2ccc(Cl)cc21)N1CCCC1 +CCS(=O)(=O)c1ccccc1C(=O)OCc1ccccc1C#N +O=c1c2cn[nH]c2nc(SCc2ccccn2)n1-c1ccccc1 +CCc1nc(C)c(C(C)N(C)Cc2ccccc2-n2cccn2)s1 +Cc1cccc(NC(=O)CNC(=O)CCC(C)C)c1C +COCCNC(=O)c1ccc(NC(=O)c2cccs2)cc1 +CCCC(=O)N1CCC(C(=O)Oc2cccc(F)c2)CC1 +COc1ccc(C(=O)Nc2cnc3c(c2)c(C)nn3C)cc1 +CCC(c1ccccc1)c1nnc(NC(=O)c2ccc(F)nc2)s1 +Cc1nc(OCC(=O)Nc2ccc(Cl)cc2F)c2ccccc2n1 +C=CCNC(=O)c1cc2ccc(OC(=O)C(C)(C)C)cc2oc1=O +Cn1c(SCC(=O)c2ccc(F)cc2)nnc1-c1ccccc1N +CCC1CN(CC(=O)N2CCCC2)c2cc(N)ccc2O1 +CC(=O)c1ccc(NC(=O)NCC(O)c2ccsc2)cc1C +COc1ccc(C(=O)NC2CCC(C)CC2)c(O)c1 +CC(C)(NC(=O)C1CC(=O)N(CC2CC2)C1)c1ccccc1 +Cc1cn[nH]c1C1(C)CCN(C(=O)Cc2ccccc2)CC1 +CSc1nccc(-c2cccc3cccnc23)n1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCOCC2)cc1Cl +Cc1cc(NC(=O)c2c(F)cccc2Cl)nn1C +Cc1cnc2c(C(=O)N(C)Cc3cn[nH]c3-c3ccccc3)cnn2c1 +COC(=O)c1ccccc1NC(O)c1ccc(C)cc1 +Cc1ccc(-c2n[nH]c3c2C(c2ccccc2)NC3=O)cc1 +COCCNC(=O)C(C)Sc1nnc(-c2ccoc2C)n1C +CCSc1cc(C(=O)Nc2c(C)cc(C)cc2C)ccn1 +CC(=O)NC(CC(=O)NC(C)c1ccc(F)c(F)c1)c1ccccc1 +CC12CCC(C(=O)N(CCC#N)CCC#N)(OC1=O)C2(C)C +CC(C)CC(CO)NC(=O)c1cccc(Br)c1 +CC(C#N)(c1ccccc1)S(=O)(=O)c1cccnc1 +COc1ccc(-c2noc(-c3n[nH]c(=O)c4ccccc34)n2)cc1 +COc1cccc(CNc2nc3ccccc3c(=O)n2CCCO)c1 +COc1ccc(NC(=O)c2ccccc2C)cc1N +CCN1C(=O)c2cc(Cl)ccc2NC1c1cscn1 +NC(=O)c1nn(-c2c(F)cccc2F)c2c1C(=O)CCC2 +Cn1cc(Cl)cc1C(=O)Oc1cccc(S(C)(=O)=O)c1 +O=C(Cn1ncc(=O)c2ccccc21)Oc1c(Cl)cccc1Cl +O=C(CC1CC2CCC1C2)NCc1nc2ccccc2[nH]1 +C=C(C)CN(CC)C(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 +CC(C)(C)n1cc(-c2cnn(Cc3ccccc3)c2)cn1 +COc1ccc(C(=O)Oc2ccc3c(c2)ncn3C)cc1 +CCOCCNS(=O)(=O)N1CCCCCC1 +Cc1ccc(C(=O)NC2(c3ccc(F)cc3F)CCOCC2)c(=O)[nH]1 +Cc1ccsc1C(=O)Oc1ccc(NS(C)(=O)=O)cc1 +CCc1nnsc1C(=O)NCc1nnc2ccccn12 +CCC(=O)c1ccc(OCC(=O)Nc2cc(F)ccc2F)cc1 +COc1ccc(NC(=O)C(C)NC(=O)c2ccco2)cc1 +CCc1ccc(OCCCC(=O)Nc2nc[nH]n2)cc1 +Cn1ncc2c1CCCC2NC(=O)NCc1ccc(C#N)cc1F +CNC(=O)CC(C#N)c1cc(OC)c(C)cc1OC +COc1ccc(OCc2nc(C)cs2)cc1OC +Cc1cc(=O)[nH]c(-n2nc(-c3ccco3)cc2NC(=O)C(C)(C)C)n1 +CC(NC(=O)c1ccc2cc[nH]c2c1)c1ccc2c(c1)NC(=O)CO2 +CCNC(=O)c1ccc(-c2ccc(OC)c(OC)c2)nc1N +O=C(c1cccc(-c2ccoc2)c1)N(Cc1ccco1)CC(F)(F)F +O=c1cc[nH]cc1NCc1ccc2ccccc2c1 +C#CCN1CCN(Cc2noc(Cc3ccccc3)n2)CC1 +COc1cccc(C(=O)NCCCNC(=O)c2ccco2)c1 +CCc1nnc(NC(=O)CCOc2ccc(Cl)cc2)s1 +O=C(Cc1ccc(F)cc1)Nc1ccc2c(c1)CCC(=O)N2 +COC(=O)c1cccc(CC(=O)N(C)c2ccc(Cl)cn2)c1 +Cc1ccc(S(=O)(=O)NCc2ccc(NC(N)=O)cc2)cc1F +CN(C1CCCc2ccccc21)S(=O)(=O)Cc1ccc(C#N)cc1 +CC(NC(=O)Cn1cnnn1)c1cc2ccccc2o1 +CCCC(C)C(=O)N1CCN(C(=O)c2ccco2)CC1 +Cc1nnc(NC(=O)CN2CCCCC2=O)s1 +O=C(Cn1cnc(C2CCC2)cc1=O)c1c[nH]c2ccccc12 +CC(C)(C(=O)N1CCCN(c2ccc(F)cc2)CC1)N1CCOCC1 +CCCOc1cccc(CNC(=O)c2csc(C)n2)c1 +CCc1noc(C2CCCCN2C(=O)C2CC2c2ccccc2)n1 +CCCc1nc(CNc2ccc(CC(=O)N(C)C)cc2)cs1 +CC(=O)N1CCN(C(C(=O)NC2CC2)c2ccc(F)cc2)CC1 +Cc1cccc(OC(C)c2nnc(SCC(N)=O)n2C)c1C +Cc1n[nH]c(C)c1-c1cc(-c2ccc[nH]2)nc(N)c1C#N +Cc1nn(CCC#N)c(C)c1CCC(=O)Nc1nc(C(C)C)cs1 +Cc1cc(O)c(C(C)C)cc1NC(=O)c1ccnc(N(C)C)c1 +CCn1ccc(C(=O)Nc2ccc(C(F)(F)F)cc2Cl)n1 +Cc1ccnc(NC(=O)c2cc3occc3n2C)c1 +O=C(NCCC(=O)N1CCCC1)c1ccc(-n2cnnn2)cc1 +NC(=O)Cn1ccn(-c2cccc3ccccc23)c(=O)c1=O +Cc1ccccc1-c1nnc(CNc2cc(CO)ccc2Cl)o1 +O=C(Nc1cnn(Cc2cccc3ccccc23)c1)c1ccncc1 +COc1cc2c(cc1Cl)C(c1ncccn1)NCC2 +CNC(=O)c1nnn(Cc2ccccc2)c1NC(C)=O +CCCNC(=O)Cc1csc(NC(=O)OC)n1 +COC(=O)C(C)CNc1cc(OC)c(Cl)cc1OC +CC(=O)Nc1ccc2nc(Cc3ccccc3)oc2c1 +CC(Sc1nccn1C)C(=O)N1CCC(C(N)=O)CC1 +CNC(=O)Nc1ccc(NC(=O)c2ccc(O)c(Cl)c2)cc1 +COC(=O)CSc1nc(-c2ccc(Br)cc2)c[nH]1 +O=C(CCn1nnc2ccccc2c1=O)Oc1ccc2ccccc2c1 +Cc1cnc(NC(=O)NCCN2CCN(c3ncccn3)CC2)o1 +Cc1cccc(C2CC(=O)Nc3c2cnn3-c2ccccc2)c1 +C=CCN1CCN(C(=O)COc2ccccc2)CC1 +Cc1ccc(N2CCN(C(=O)c3ccc(C(C)(C)C)cc3)CC2)nn1 +O=c1c2nnn(-c3ccc(F)cc3)c2ncn1Cc1ccc(F)cc1 +CNC(=O)C1CCC(NC(=O)C2(c3cccc(C)c3)CCCC2)CC1 +CCc1nn(C)cc1CNC(=O)NC1CC(C)(C)OC1(C)C +Cc1ccc(C(=O)NCC(=O)NCC2CCOC2)cc1 +C#Cc1cccc(NC(=O)C(C)n2nc(C)cc2C)c1 +CC(C)Oc1ccc(Br)cc1C(N)=O +Cn1cc(C(=O)Nc2cnc(-c3ccccc3)nc2)ccc1=O +O=C(NCC1(O)CCOCC1)N(c1ccccc1)c1ccccc1 +Cc1cccnc1C(NC(=O)c1cccc(OCC(F)F)n1)C(C)C +Cc1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)cc1F +O=C(NCC1(c2ccc(F)cc2F)CC1)C1COc2ccccc21 +c1cn(-c2ccc(NC(C3CC3)C3CC3)cn2)cn1 +COCCN(Cc1ccc(F)c(C)c1)CC(F)F +Cc1ccc(-c2noc(C(C)(C)NS(C)(=O)=O)n2)cc1F +C#CCOC(=O)c1cnc(-c2ccccc2F)s1 +Cc1noc(-c2csc(C(=O)NCc3ccccn3)n2)n1 +Brc1ccc2sc3c(c2c1)CCNC3 +CCS(=O)(=O)NC(Cc1ccccc1)C(=O)NC1CC1 +Cc1ccccc1NC(=O)c1cnc(C2CCCO2)nc1N +O=C(Nc1ccc(-n2ccnc2)nc1)c1cn(Cc2ccccc2)nn1 +CCNC(=O)CNC(=O)C(C(C)C)n1nnc(-c2ccccc2)n1 +Cc1cccc(OCC(O)CNC(=O)c2ccco2)c1 +Cc1cccc(C(=O)Nc2ccccc2C(=O)N(C)C(C)C)c1 +CCc1ccsc1C(=O)NCc1cccc(C)n1 +Cc1ccc(O)c(C(=O)c2cnn(-c3ncnc4c3cnn4C)c2)c1 +COc1cc2c(cc1O)C(c1ccncc1C)NCC2 +O=C(COc1ccccc1)NCC(=O)Nc1cc(-c2ccco2)no1 +Cc1ccc(CNC(=O)Nc2ccc(-n3cnnn3)c(C)c2)c(C)c1 +O=C(CN1CCN(Cc2cccs2)CC1)N1CCCC1 +O=C(Nc1cccc(-c2noc(C3CCC3)n2)c1)c1cccs1 +COC1CCCCC1NC(=O)Nc1cc(C)cc2cccnc12 +C=C1CCC2C(OC(=O)C2(O)CO)C2C(=C)C(O)CC12 +COc1ccccc1Cn1ccn(Cc2ccc(C)cc2)c(=O)c1=O +Cc1ccc(C(=O)NC(C)(C)CNC(=O)OC(C)(C)C)cn1 +N#CCn1ccc(NC(=O)c2ccc3c(c2)OCCO3)n1 +Cc1ccc(N2CCC3(CC2)CCN3c2ncccn2)nn1 +Cc1cc(NC(=O)CCC2CCCO2)n(-c2ccc(Cl)cc2)n1 +NC(=O)c1cccc(COC(=O)c2ccc(-n3cccn3)c(F)c2)c1 +Cc1c(C(=O)NCC2CC2)cnn1-c1ccncc1 +CCc1nc(CN(C)Cc2c(Cl)ccc(O)c2Cl)no1 +COc1cccc(CCNC(=O)C(N)Cc2ccccc2)c1 +N#Cc1cccnc1N1CCCN(C(=O)C2CC2(Cl)Cl)CC1 +COc1ccccc1C1(CNC(=O)c2csnn2)CCCC1 +CN(CCc1ccccn1)C(=O)Cc1c(F)cccc1F +CCS(=O)(=O)c1cc(OC)c2c(c1OC)CNC(C)C2 +Nc1ccc(C2=CCC3(CC2)OCCO3)c(Cl)c1 +CC1CCc2c(sc3nc(CCC(=O)N4CCCC4)[nH]c(=O)c23)C1 +COC(=O)c1ccc(Cn2ccc(=O)c3ccc(Cl)cc32)o1 +COc1ccc(OC)c(CC(=O)Nc2cccc(C(C)=O)c2)c1 +Cc1cc(=O)c(C(=O)Nc2cc(Br)ccc2O)c[nH]1 +Cc1nnc2n1CC(NC(=O)c1cc(-c3ccccc3F)on1)CC2 +COC(=O)CC(NC(=O)c1ccc(F)c(F)c1)C1CC1 +N#Cc1ccc(Cn2nc(C#N)cc2-c2ccncc2)cc1 +COc1ccc(NC(C)=O)cc1NC(=O)CCC(=O)c1cccs1 +COCCCCS(=O)(=O)c1ccc(C(F)(F)F)cn1 +CCc1c(C(=O)Nc2ccccc2O)cnn1Cc1ccccc1 +CS(=O)(=O)NCC1(c2ccccc2)CCCCC1 +Brc1ccnc(-c2cc(Br)ccn2)c1 +Nc1cc(Br)cnc1OCC(F)(F)F +Cc1cnn(C)c1C(=O)Nc1nc2c(Cl)cccc2s1 +CC(C)CNC(=O)NCC1CCN(C)c2ccccc21 +CN(CC(=O)N1CCNCC1)S(=O)(=O)c1cnn(C)c1 +CC(=O)c1cccc(NC(=O)CCc2ccsc2)c1 +O=S(=O)(NCc1ccccn1)c1ccc(O)cc1 +CC(=O)c1c2c(nc3c(C)cc(Cl)cc13)CCN(C)C2 +O=C(Nc1ccccc1)C1CCCN1c1ncnc2sccc12 +CCC(C)NC(=O)C(CC(C)C)NS(C)(=O)=O +COCC(C)NC(=O)Nc1ccccc1SCC(C)C#N +COc1cccc(-c2noc(-c3ccc(N)nc3)n2)c1 +O=S(=O)(NCCc1ccccn1)c1ccc(F)cc1 +Cc1nc(C(C)C)sc1C(=O)N1CCC2(CN(C)C(=O)O2)C1 +CC1CN(C(=O)CN(C)S(=O)(=O)c2cccnc2)c2ccccc21 +CCC1C(=O)Nc2ccc(C(O)c3cccc(OC)c3)cc21 +COc1ccc(-c2nc(C(=O)N(C)CC(N)=O)cs2)cc1OC +O=S(=O)(NCc1ccccc1)c1ccc(N2CCCCC2)cc1 +CCOc1ccccc1-n1ncc(C(=O)OC)c1N +NS(=O)(=O)c1cc(C(=O)NCCNC(=O)C2CC2)cs1 +CC1CCCC(NC(=O)Cc2csc(N3CCCC3=O)n2)C1C +COc1cc(C(=O)N(C)c2ccc(C)cc2C)cc2c1OCCO2 +N#Cc1nnn(Cc2ccc(Cl)cc2)c1C1CCCO1 +O=C(COc1ccc(Cl)cc1)NCCc1ccsc1 +NC(=O)C(NC(=O)c1ccc(-c2ccccc2)[nH]1)c1ccccc1 +CCC(C(=O)NC1CCc2cc(F)ccc21)c1c(C)noc1C +CCc1noc(CC)c1CNC(=O)NC(CC)c1ccc(Cl)cc1 +CCC1(CNC(=O)NCCCc2c(C)noc2C)CCC1 +CCCCCn1ccc2c(nnc3ncnn32)c1=O +Cc1ccc(OCC(=O)Nc2nc(C3CC3)cs2)cc1 +COC(=O)CCSc1nnc(-c2ccc[nH]2)o1 +CCOc1cccc(CC(=O)Nc2c(C)noc2CC)c1 +CC(=O)NCCc1nc(CCc2ccccc2)nn1-c1ccccn1 +Cc1ccn2cc(CNC(=O)c3ccc(-c4ccco4)[nH]c3=O)nc2c1 +COCC(=O)Nc1nnc(SCC(=O)c2ccccc2)s1 +N#CCc1ccccc1C(=O)NCc1ccccc1Cl +CCn1cc(NC(=O)N2CC(C)OC(c3ccsc3)C2)ccc1=O +CN(CCc1ccccc1)C(=O)c1c[nH]nc1-c1ccccc1 +COCCOc1ccccc1NC(=O)NCc1nncn1C +O=C(Nc1cccc(Cl)c1)NC1(CO)Cc2ccccc2C1 +Cc1cccc2c1N(CCc1ccccc1)C(=O)C21OCCCO1 +Cn1cc(Br)cc1C(=O)N(Cc1cccs1)C1CC1 +NS(=O)(=O)c1cc2c(c(Cl)c1Cl)NCNS2(=O)=O +CCOc1ccc(S(=O)(=O)NC(C#N)C(C)C)cc1 +Fc1ccc(OCC2CCCO2)c(Br)c1 +COc1c(C)cc(Cl)cc1-c1n[nH]c(C)c1N +NC(=O)N1CCC(NC(=O)C2CC3CCC2O3)CC1 +CC(C)CC(C)OCCC(=O)Nc1cc(N)ccc1F +O=C(CNc1ccccc1)CN1CCN(c2ccccc2)CC1 +CC(=O)Nc1cc(NCC(=O)N(C)C2CCC(C)CC2)ccc1F +O=C(NCCNC(=O)C1CCCCC1)c1cnc2ccoc2c1 +COCCC1CCN(C(=O)c2cc(F)ccc2Cl)CC1 +CCC(C)(C)NC(=O)COc1cccc(-c2nnco2)c1 +CC(=O)c1ccc(NC(=O)C2CN(C(=O)c3cccs3)C2)cc1 +CCOC(=O)CNC(=O)c1nc(OCC)ccc1Cl +CC(Sc1nnc(C(F)(F)F)n1N)c1ccc(F)cc1F +CCn1cnnc1CNC(=O)N(C)Cc1cccc(Cl)c1Cl +O=C(Nc1ccc(NC(=O)C(O)c2ccccc2)cc1)c1ccco1 +O=C(NCc1cscn1)NC(c1ccccc1)c1ccccc1 +COc1cccc2c(=O)n(CC(=O)Nc3cc(C)ccc3C)ccc12 +CCn1cc(NC(=O)c2nn(C)cc2Cl)c(C(N)=O)n1 +NS(=O)(=O)c1ccc(NCC2COCCO2)cc1 +N#Cc1c(NC(=O)c2n[nH]cc2N)sc2c1CCC2 +COCCCn1c(=O)c2ccccc2n(Cc2cccc(C)c2)c1=O +O=C(Nc1ccc2c(c1)OCCCO2)c1cccnc1 +CC(C#N)Sc1nnc(C2CC2)n1Cc1ccco1 +Cc1nc(NCCN2CCCOC2=O)c2ccsc2n1 +O=C(c1cc(C2CC2)nc2onc(-c3ccco3)c12)N1CCCC1 +CC(Cc1ccccc1Cl)NC(=O)Cn1cnnn1 +Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)NCC(C)C)cc1 +Clc1ccc(OCCn2ccnc2)c(Cl)c1 +CCOCCOc1c(Cl)cccc1NC(=O)c1ccnnc1 +Cc1nc(C(C)(C)NS(=O)(=O)Cc2ccccc2F)sc1C +Cc1nn(C)c(C)c1C1COCCN1C(=O)Cc1ccc(F)cc1 +N#Cc1ccccc1Cn1ccnc1Cc1nccs1 +CC1CCC(C(=O)Nc2ccc(CN3CCOCC3)c(Cl)c2)O1 +C#CCOc1ccc(C(=O)NCc2ccc(C)cc2)cc1 +O=C(c1ccccc1)N1CCC(C(=O)N2CCc3ccccc32)CC1 +O=C(CN1CCOCC1)c1ccc(Br)cc1 +Cc1nn(C)c(C)c1C(C)NC(=O)c1ccccc1 +COc1nc(C)cc(C(=O)NCC2CCCO2)n1 +C#CCN1CCC(C(=O)N(C)C2(C#N)CCC2)CC1 +CCCC(=O)Nc1nnc(-c2cc(N)ccc2F)s1 +Cc1noc(C)c1CC(=O)NS(=O)(=O)N(C)Cc1ccccc1 +Cc1ncc(-c2ccccn2)c(CN(C)C(=O)c2ccccn2)n1 +NC(=O)c1csc(C(=O)N(Cc2ccc(F)cc2)C2CC2)c1 +COc1ccccc1-c1nnc(-c2cccc(N)c2)o1 +O=C(CCc1c[nH]c2ccccc12)NCCC(F)(F)F +CCNC(=O)c1ccc(NC(=O)CNc2c(C)cc(C)cc2C)cc1 +CCC1CCCCN1C(=O)NCCNC(=O)C1CC1 +COC(=O)c1ccc(Cn2nc(-c3cccs3)ccc2=O)o1 +O=C(NC1CCCCC1)c1cc(N2CCCC2=O)ccc1Cl +CCC(NC(=O)NCCNC(C)=O)c1cc(F)ccc1F +CCN(CC1CCCO1)C(=O)Nc1ccccc1OCC1CC1 +Cc1cc(N2CCCC(C(N)=O)C2)nc(-c2ccncc2)n1 +CCc1ccsc1C(=O)N1CCC(c2nc(C)no2)CC1 +CC(CCc1ccc(OC(C)C)cc1)NS(C)(=O)=O +CCOC(=O)C(Cc1nnc(-c2ccccc2)o1)NC +Cc1ccc(NC(=O)C2CC3CCC2O3)cc1C(N)=O +COc1ccc(F)c(NC(=O)N2CCN(c3nccs3)CC2)c1 +CCC(=O)Nc1cccc(NC(=O)NC(C)(C)CO)c1 +COc1ccccc1CN(Cc1cccs1)C(=O)c1cccn1C +Cc1ccsc1CN1CCCC1c1nc(-c2ccccn2)no1 +Cc1ccc(NC(=O)c2ccccc2)cc1NC(N)=O +Cc1nc(C(=O)Nc2ccc(F)cc2C)cs1 +O=C(Cc1ccc(F)cc1)N1CCC1c1nc(-c2cccnc2)no1 +NS(=O)(=O)c1cc(Cl)c(Cl)c(S(N)(=O)=O)c1 +CC(C)N1C2COCC1CN(C(=O)c1cccc(C#N)c1)C2 +COC(=O)c1ccccc1-n1nc(C(N)=O)c2c1CCNC2 +CC(CNc1ncccc1C#N)c1nc2ccccc2o1 +CCc1ccc2c(c1)c1nnc(SCC(=O)NC3CC3)nc1n2C +O=C(CCNC(=O)c1cccs1)OCC(=O)N1CCCCCC1 +COC(=O)N1CCC(CNC(=O)Nc2ccccc2)CC1 +CC(C)CC1COCCN1C(=O)NC(C)c1ccncc1 +COc1ncccc1CNC(=O)Nc1ccc2oc(C3CC3)nc2c1 +Cc1ccccc1Cn1cccc(C(=O)Nc2ccccc2F)c1=O +Cc1cn2cc(C(=O)Nc3nc4ccccc4s3)sc2n1 +Cc1cc(C(C)NC(=O)N2CCOC(C(N)=O)C2)c(C)o1 +O=C(Nc1ccc(Cl)c(F)c1)Nc1cnn(CC2CCCO2)c1 +NC(=O)c1cccc(CNC(=O)c2cn3cccnc3n2)c1 +CCn1nnc2c(NCCc3ccccc3)ncnc21 +Cc1ccc(C(=O)Nc2cccc(NC(=O)C3CC3)c2)cc1 +Cc1noc(NC(=O)COc2ccc(F)cc2)n1 +CCn1c(SCC(=O)N(C)C)nc2sc(C)c(C)c2c1=O +NC(=O)CCOc1ccccc1NC(=O)c1c[nH]c2cccc(F)c12 +CCCNC(=O)c1nnn(-c2ccc(C)c(C)c2)c1C +CC(C)C(NC(=O)Cn1cnc(C#N)n1)c1ccccc1 +COC(=O)Cn1ccc(NC(=O)OCc2ccccc2)nc1=O +Cc1cccc(-c2noc(C(=O)Nc3cccnc3)c2N)c1 +CN(C)c1c(Cl)cccc1NC(=O)c1cc(Cl)c[nH]1 +COCCN1CC(CNc2ncnc3nc(C)cc(C)c23)CC1=O +CCOC(=O)CCCNc1nc2cc(C)ccc2s1 +Cc1ccc(-c2cc(C(=O)NCCCc3nccs3)on2)cc1 +NC(=O)CC1CCN(C(=O)c2c3c(nc4ccccc24)CCC3)CC1 +Cc1nc(C(=O)Nc2ccc(C(C)(C)C)cc2)cs1 +COc1ccc(-c2noc(COc3ccc(C#N)cc3OC)n2)cc1 +CC(C)n1cnnc1S(=O)(=O)Cc1ccc(Cl)cc1Cl +Cc1nc(CCNC(=O)NC(C)c2ccncc2)cs1 +CCCN(CC1CC1)C(=O)c1cc(=O)[nH]c2ccccc12 +COc1cc2nc(-c3ccc(N)cc3)n(CCC#N)c2cc1OC +CC(O)c1ccccc1NS(=O)(=O)N(C)C(C)C +O=C(Nc1cnc2ccccc2c1)c1ccc2cncn2c1 +Cc1ccc(NC(=O)CC(C)n2cccn2)c(Cl)c1 +CCn1c(CCNC(=O)c2cccc(Cl)c2)nc2cccnc21 +CC(=O)c1ccc(C(=O)N2c3ccccc3CC2C)s1 +CC(=O)NCC1CCCN(C(=O)CCSc2ccccc2F)C1 +Cc1cc(C(=O)NCc2c(C)nn(C)c2C)c2c(C)nn(C)c2n1 +O=C(Cc1coc2ccc(F)cc12)Nc1ccccc1Cl +Cc1cc(C(=O)NCC(=O)NCCn2cc(Cl)cn2)nn1C +CC(C)N1CCC(Sc2nnc3n(C)c4ccccc4n23)C1=O +COC(=O)N1CCC(NC(=O)NCc2ccc(C)c(F)c2)CC1 +CC(Sc1nc(-c2ccccc2)n[nH]1)c1nc(N)nc(N(C)C)n1 +CNC(=O)c1ccccc1NC(=O)C1CC2C=CC1C2 +CC(C)C(NC(N)=O)C(=O)Nc1ccc(Br)cc1 +O=C(CS(=O)(=O)c1ccc(F)cc1)Nc1cc(F)ccc1F +CC(c1ccccc1)S(=O)(=O)c1ccc(C(F)(F)F)cn1 +CCN(CC)C(=O)c1cn(CCC#N)nc1-c1cccc(OC)c1 +Cc1ccc(OCC(=O)Nc2cccc(-c3nncn3C)c2)cc1 +COc1cccc(NC2CCN(C(=O)C3CCOCC3)CC2)c1 +Cc1cccc(C)c1NC(=O)c1nccc2c(N)c(Cl)ccc12 +CCOc1ncccc1NC(=O)N1CCc2sccc2C1 +CNC(=O)C(O)c1ccc2c(c1)nc(C)n2C(C)C +COc1ccc(OC)c(S(=O)(=O)NCc2ccccn2)c1 +Cn1cc(C(=O)NCCOc2ccccc2)ccc1=O +N#Cc1ccc(C(=O)NCC2(c3ccccc3)CCOCC2)cc1 +CCOc1ccccc1CNC(=O)N1CCC(CC(N)=O)CC1 +Cc1ncc(CNC(=O)Nc2cccc(NC(=O)C(C)C)c2)s1 +CCCOc1cccc(NCC(=O)N2CCC(C)CC2)c1 +O=C1OC(C(=O)Oc2ccc3c(c2)OCO3)Cc2ccccc21 +CNC(=O)CSc1nnc(-c2ccccc2)c2sc(C)nc12 +Cc1noc(CCC(=O)Nc2cccc(OCc3cccnc3)c2)n1 +Cc1ncc2c(n1)CN(Cc1nc(-c3ccccc3C)no1)CC2 +COC(=O)Nc1cccc(NCC(=O)Nc2ccc(C)cc2C)c1 +COc1ccc(CN(C)c2ccc(-c3nc(C)cc(=O)[nH]3)cn2)cc1 +CC(=O)N1CCCC1c1cccc(-c2cccc(C)c2C)n1 +Cc1onc(-c2ccccc2Cl)c1C(=O)NC(C)(C)CCO +Cc1c(C(=O)N2C3CCC2CC(O)C3)sc2ncn(C)c(=O)c12 +Cc1cccc(CSc2ncnc3nc[nH]c23)c1 +O=C1CCC(COC(=O)Cc2ccc(N3CCCC3=O)cc2)N1 +Cc1cc(NC(=O)c2ccco2)sc1C(=O)NCc1cscn1 +Cc1cccc(NS(=O)(=O)c2cccc(O)c2)c1C +COc1cc(N)cc2cc(-c3cc(C(=O)OC(C)C)n(C)n3)oc12 +CC(C)(C)NC(=O)c1cccc(Br)c1N +Cc1sc2nc(C(C)C)n(CC#N)c(=O)c2c1C +CCc1cccc2c(C(=O)CN3CCN(c4ncccn4)CC3)c[nH]c12 +CC(C)(C)OC(=O)c1[nH]c2c(c1N)C(=O)CCC2 +CCn1nnnc1NCc1ccc2c(c1)n(C)c(=O)n2C +CC(=O)NCc1ccc(C(=O)Nc2ccc(C)c(C(N)=O)c2)s1 +O=C(CCCOc1ccccc1)N1CCOCC1C1CC1 +COC(=O)c1ccc(C(=O)Nc2ccccc2C(=O)NC2CC2)cc1 +O=C(NC1CCc2ccccc21)c1cc(-c2ccccc2)[nH]n1 +CCc1cc(C#N)c(NC(=O)c2cccc3ncccc23)s1 +CCOc1cc(CO)ccc1OCC(=O)Nc1ccc(C)cc1 +O=C(NCCN1CCOCC1)N1CCCCC1CCO +Cc1cc(C)n2c(CNc3cnn(CC(C)C)c3)cnc2n1 +Cc1c(C(=O)Nc2ccccc2C(=O)C(C)C)cnn1C +CCC(NC(=O)Cc1ccc[nH]1)c1nc(-c2ccccc2)c[nH]1 +CCOCCCNc1nc(-c2ccc3c(c2)CC(=O)N3C)cs1 +Cc1cc(NC(=O)CCc2ccc(C3CC3C)o2)no1 +Cc1c(Cl)cccc1NCCC(=O)NC1CC1 +O=C(NCC1CCN(C(=O)c2ccoc2)CC1)c1cc(C2CC2)on1 +COCCNC(=O)c1ccc2c(c1)nnn2Cc1ccccc1C +c1ccc(N2CCCC2)c(-c2nc(C3CCOC3)no2)c1 +O=C(Cc1c[nH]c2ccccc12)Nc1ccc(-c2cc[nH]n2)cc1 +CC(O)CNC(=O)c1nc(-c2ccc(F)cc2)no1 +O=C(Nc1cc(F)cc(N2CCCC2)c1)c1ccco1 +O=C(C1CC(=O)N(C2CCCCCC2)C1)N1CCCC1 +Cc1c(C(=O)Oc2ccc3c(c2)OCCO3)cnn1C +CCCCC(=O)Nc1cnn(C2CCOCC2)c1 +Fc1cccc(-c2nc(C3CCOC3)no2)c1Cl +CC1CCN(S(=O)(=O)c2ccc(-c3ccno3)s2)CC1 +CCc1[nH]nc(C(=O)Nc2ncc(C)s2)c1N +O=C(CCC1(Cc2ccco2)CCC(=O)N1)NCc1cccc(F)c1 +COc1ccc2cc(Br)ccc2c1CO +Cc1csc(CCCCNC(=O)Cc2ccc(F)cc2F)n1 +CCC(=O)Nc1c(C(=O)Nc2cccc(OC)c2)oc2ccccc12 +Cc1noc2nc(-c3ccco3)cc(C(=O)Nc3ccc(C#N)cc3)c12 +CCOc1ccccc1NC(=O)CCn1cnnn1 +Cc1ccc(NCCC(=O)NC(C)C)c(Br)c1 +CC(=O)Oc1cc(OCc2ccccc2)ccc1C#N +Cc1ccc(O)c(C(=O)NCCOc2cccnc2)c1 +CCOC(=O)c1cc(C)n(-c2ccccc2Br)n1 +COc1cc(O)cc2c1CCNC2c1cnoc1C +CCOC(=O)c1cc2cccc(C(=O)OC)c2[nH]c1=O +CCCCn1c(C(C)OCCC#N)nc2ccccc21 +CCN(CC)C(=O)Cc1n[nH]c2cc(Cl)ccc12 +Cc1ccccc1CN(C)C(=O)c1ccc(N2CCC(O)CC2)cc1 +O=C(NCc1nc(-c2ccccc2Cl)no1)c1cccc(F)c1 +CCC(CC)c1c(CO)nnn1CC(=O)Nc1ccccn1 +CCc1onc(C)c1NC(=O)C1CC(=O)N(CCOC)C1 +O=C(COC1CCCCC1)N1CCN(C(=O)c2cccc(O)c2)CC1 +COCc1nnc(NC(=O)CSc2nc3ccccc3[nH]2)o1 +COc1ccc(-c2nnc3sc(-c4ccncc4)nn23)cc1 +Cc1ccc(Nc2ncccc2S(=O)(=O)N2CCCC2)cc1 +COCC(O)CN(C)C(=O)Nc1cc(Cl)ccc1Cl +Cc1noc(C(NC(=O)NCC2CCCO2)C(C)C)n1 +Cc1ccc(Cn2ccc(=O)n(CC(=O)NC(C)C)c2=O)cc1 +CC(Nc1cccc(CO)c1)C(=O)N(C(C)C)C(C)C +COc1ccccc1COc1cccc(F)c1C#N +CCCCOC(=O)CCN1CCOC2CCCCC21 +Nc1ccc(Cl)c(-c2nnc(N3CCCCC3)o2)c1 +NC(=O)Nc1cccc(NC(=O)CCc2ccc(F)c(F)c2)c1 +Cc1[nH]ncc1S(=O)(=O)NC(C)CCC(C)C +CCC(=O)Nc1ccc(C)c(NC(=O)c2scnc2C2CC2)c1 +C=CCN1C(=O)CCCC12CCCN(C(=O)c1ccc(CC)cc1)C2 +c1cc(CN2CCOC3CCC2C3OCC2CC2)cs1 +COc1ccc(CNc2ccc(F)cc2F)cc1OC +NC(=O)c1cc(CC2COCCN(C(=O)c3ccccc3)C2)ncn1 +COC(=O)CCCc1ccc2c(c1)nc(C)n2C1CC1 +Cn1cnc(S(=O)(=O)NCCC(O)c2ccco2)c1 +Cc1cc(CN(C)C(=O)NCc2ccccn2)no1 +O=C(NCCc1csc(-n2cccn2)n1)c1ccc(F)cc1F +O=C(Cn1cnc2ccsc2c1=O)NCc1ccco1 +COCc1ccc(CN2CCC(N3CCOC(C)C3)CC2)cc1 +CCC(NC(=O)NC(C)(C)CC)c1ncc(C)s1 +COc1c(C2CCCN2CCc2ccccn2)c(C)nn1C +COc1ccc(OS(=O)(=O)c2ccc(C(C)=O)cc2)cc1 +COc1ccc(-c2nc(C)sc2C(=O)Nc2cnn(C)c2)cc1 +CC(=O)N1CCC(NC(=O)c2ccccc2-n2cccn2)CC1 +CCc1ccc(OCC(=O)NCC(F)(F)F)cc1 +O=C(COC(=O)c1cccs1)Nc1ncc(Cl)cc1Cl +CCC(C)C(C)NC(=O)Nc1ccc(NC(C)=O)c(OC)c1 +CC(C)CCn1c(CNC(=O)c2ccccn2)nc2ccccc21 +COc1ccc(CNC(=O)C2CC(=O)N(Cc3ccccc3)C2)cc1 +C#CCN1CCN(C(=O)c2cc(C)ccc2F)CC1 +CCc1nnc(NC(=O)C2CC(=O)N(c3ccc(C)cc3C)C2)s1 +Cc1cc(C)c(CNC(=O)NC(C)c2ccc3c(c2)CCC3)c(=O)[nH]1 +CCc1onc(C)c1NC(=O)NC(C(=O)OC(C)(C)C)C(C)C +CC(C)c1cccc(NC(=O)c2cn(C)n3cccc3c2=O)c1 +COc1ccc(CNC(=O)c2cccc(Cl)c2Cl)cc1OC +O=S(=O)(C1CC1)N1CCC(Oc2ccccn2)CC1 +Cc1ccc(C)c(CNc2cc(S(C)(=O)=O)ccc2C)c1 +c1cnc(-c2cnc(N3CCCCC3)nc2C2CCCO2)cn1 +O=C(c1cc2ccccc2c(=O)o1)N1CCCCCC1 +COc1cccc(-c2cc(C(=O)N3CCCOCC3)[nH]n2)c1 +O=C(OCC(F)(F)F)C1CCCCC1C(=O)n1ccnc1 +CCNC(=O)C1CCCN(S(=O)(=O)c2cnn(C)c2)C1 +Cc1cccc(C(=O)NCCn2nc(-c3ccccc3)ccc2=O)c1 +CCOc1cccc2c1CCNC2c1ccnc(OC)c1 +COc1ccccc1CN(C)C(=O)NCc1cccnc1OC +CCCCC(O)c1ccc2c(c1)CN(C(=O)c1ccccc1)C2 +CCOC1CCN(C(=O)C2CC(=O)N(c3ccccc3OC)C2)CC1 +O=C(Cc1ccccc1F)NCCc1c[nH]c2ccccc12 +O=C(NCc1ccccc1)c1cn[nH]c1-c1ccccc1 +Cc1occc1C(=O)Nc1nc(-c2ccc3c(c2)OCCO3)cs1 +C#CCN1CCN(C(=O)NC(C)COc2cccc(C)c2)CC1 +O=C(Cc1ccc(F)cc1)Nc1nnc(-c2cccnc2)o1 +C#CCN1CCN(Cc2coc(-c3cccs3)n2)CC1 +C=CCNS(=O)(=O)c1ccc(OC)c(C(=O)NCC)c1 +Cc1cnc(CN2CCCN(C(=O)CCc3ccccc3)CC2)cn1 +Cc1nnc(NC(=O)C2CCN(C(=O)C(C)(C)C)CC2)s1 +Cc1ccc(SCCC(=O)N2CCCC2C(N)=O)cc1 +CCCCn1c(-c2csnn2)nc2c1c(=O)[nH]c(=O)n2CCCC +COCCN(Cc1ccccn1)C(=O)c1ccnc(-n2cncn2)c1 +CC(N)C(=O)OCc1ccc(S(=O)(=O)C(C)C)cc1 +Cc1cc2c(cc1-c1nccnc1C#N)OCCO2 +CN(CCC#N)S(=O)(=O)c1cccc(Cl)c1Cl +C1CSc2c(nc(N3CCCC3)nc2N2CCOCC2)C1 +Cc1ccccc1C1(CNC(=O)c2ccc(=O)n(C)c2)CCOCC1 +N#Cc1ccnc(N2CCN(C(=O)NCCc3ccccn3)CC2)c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)N(C)c1ccc(F)c(F)c1 +COC(=O)C(C)n1cc(CO)c2cc(F)ccc21 +O=C(NCC1CCCO1)c1cnn(-c2ccccc2)c1 +CCc1noc(C(C)S(=O)(=O)c2ccccc2F)n1 +COc1ccc(C(=O)NCC(=O)c2ccccc2)cc1OC +C=CCNc1nc2c(c(=O)n(C)c(=O)n2C)n1CCC(C)C +CC(c1ccco1)N(CCc1ccccn1)C1CC1 +CN(C)C(=O)C1CCCN(C(=O)c2csnn2)C1 +CCN(CC)C(=O)c1cc2cnn(C(C)C(C)C)c2nc1N +CC1(C(=O)Nc2nnc(C(C)(C)C)s2)Cc2ccccc2C(=O)O1 +O=C(Nc1ccc(F)c(Cl)c1)c1cc(-c2ccncc2)[nH]n1 +Cc1ccc(C)c(-n2cnnc2SCC(=O)N2CCCC(C)C2)c1 +COCCNC(=O)Nc1nc2c(OC)cccc2s1 +O=C(c1cccc(Cl)c1)N1CCCN(C(=O)C2CCC2)CC1 +CN1CCN(C(=O)c2onc(S(C)(=O)=O)c2N)CC1 +COCc1ccc(CNC(=O)NCc2cccs2)cc1 +Nc1cccc(-c2c(Cl)ccc3cnccc23)c1 +Cc1cc(NC(=O)c2cnc(N3CCCC3)nc2N)no1 +COc1ccc(C=c2sc3nc(=O)cnn3c2=O)cc1OC +CC(C)c1nnc(NC(=O)C2CC3C=CC2C3)s1 +COC(C)(C)c1noc(-c2cccc(NC(=O)c3cccnc3)c2)n1 +CC(C)(C)c1cc(NC(N)=O)n(Cc2ccccc2)n1 +CS(=O)(=O)N(CC(=O)N1CCCc2ccccc21)c1ccccc1 +Cc1cccc(CNc2cccc(N3CCCC3=O)c2)c1 +Cc1cc(C(=O)NC(c2ccccc2)c2nccn2C)sc1C +CCNC(=O)CN(CC)C(=O)c1cc(Cl)ccc1Br +COC(=O)C1C(=O)CC(C)(O)C(C(=O)OC)C1C=Cc1ccccc1 +Cc1cc(Br)c2c(c1)C(=O)C(=O)N2C(C)C +CC1CN(c2ncccc2C(=O)N2CCCC2)CC1(C)O +CCCn1cc(S(=O)(=O)NC2CCCC2)c(N)n1 +Cc1cc(=O)c(O)c(CN2CCN(CCO)CC2)n1C1CC1 +Cc1nn(C)c(C)c1-c1cc(C(=O)N(C)C2CCc3ccccc32)[nH]n1 +COC(=O)CCC(=O)N1CCOC2CCCCC21 +Cc1cc(NC(=O)c2cc(C(F)(F)F)cc(C(F)(F)F)c2)no1 +O=C(OCc1nncn1C1CC1)C1(c2ccc(F)cc2)CCC1 +CCn1cc2c(n1)CN(C(=O)CC1=CCCCC1)CC2COC +COC(=O)N(C)CCCC(=O)N1CCOCC1CC(C)C +CC(C)CN(C(=O)c1cc(Cl)ccn1)C1CC1 +COC(=O)C1CCCN1C1=NS(=O)(=O)c2ccccc21 +O=C(Nc1cnn(-c2ncccn2)c1)NC1CCc2[nH]ncc2C1 +CCS(=O)(=O)N(C)C1CCN(C(=O)Nc2cccc(C)c2)CC1 +Cn1ccnc1SCc1nnc(-c2ccccc2Cl)o1 +Cn1c2c(c(=O)c3ccccc31)CC(C(C)(O)CO)O2 +CN1C(=O)NC(c2ccc(O)cc2)C2=C1CN(CCCO)C2=O +Cc1c(CO)nnn1Cc1c(Cl)cccc1Cl +N#Cc1cc(S(N)(=O)=O)ccc1NCc1csc2ccccc12 +Cc1cccc(NC(=O)CNc2ccccc2Cl)n1 +CCOC(=O)c1cn[nH]c1NCc1cccc(F)c1 +CCCOC(=O)C(C)Sc1nc2ccsc2c(=O)n1C +Cc1ccc(CNS(=O)(=O)c2cc3n(c2)CCN(C)C3=O)cc1 +CCCNC(=O)Nc1ccccc1C(=O)N1CC(C)CC(C)C1 +CC(O)CNC(=O)c1cc(-c2cccnc2)nc2ccccc12 +Cc1nn(-c2ccccc2)c(C)c1CCC(=O)Nc1cccc(O)c1 +COc1cccc(CNC(=O)C2CC2c2cccc(O)c2)c1OC +CS(=O)(=O)N1CCC(NC(=O)CN2CCCCCC2=O)CC1 +Cc1ccc(-c2ccnc(N3CCC(=O)NCC3C)n2)c(C)n1 +O=C(OCCn1cncn1)c1ccc(Br)c(F)c1 +Cn1cc(S(=O)(=O)NCc2cc(Cl)c3c(c2)OCCO3)cn1 +O=C(NCC(=O)N1CCc2ccccc21)c1ccc(Cl)cc1Cl +CC(=O)N1CCCC1C(=O)Nc1cccc(-c2cc3ccccc3[nH]2)c1 +COc1ccc(CCNC(=O)C(C)n2cncn2)cc1OC +O=C(NCC1COCCO1)c1cc2c(s1)CCC2 +CC(=O)N(C)C1CCN(c2ccc(F)cc2)CC1 +CC1CCN(C(=O)C2Cc3cc(F)ccc3O2)C(C)C1 +Cc1ccc(Cl)cc1NC(=O)c1ccncc1F +O=C(c1cc(C2CC2)[nH]n1)N1CCCC1Cc1ccccc1 +O=C(COc1cccnc1)NCCCn1ncccc1=O +CNC(=O)C1CCC(Nc2ncnc3ccsc23)CC1 +CC(C)OC(=O)C1CCCN1Cc1cc(F)cc(F)c1 +CCCC(C)(C)NC(=O)c1cccc(-n2cnnn2)c1 +Nc1cccc(OCc2nnc(N3CCCCC3)o2)c1 +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)N(C)C1CCCCCC1 +Cc1csc(C(C)NC(=O)C2COc3ccc(F)cc3C2)n1 +O=C(NCC(O)C1CC1)C1CNc2ccccc2O1 +CC(=O)c1ccccc1NC(=O)Cn1nnnc1C(C)(C)C +NC(=O)C1CCN(C(=O)c2ccc(F)cc2Cl)C1 +Cc1ccc(CNC(=O)c2nn(-c3ccccc3)c3c2COC3)o1 +Cc1ccc(-c2noc(CCC(=O)N3CCCC(C)C3)n2)cc1 +Cc1ccc(NC(=O)Nc2c(C)noc2C)cc1Cl +COCCCOC(C)C(=O)Nc1ccc(F)cc1N +Cc1ccc(C(C)NC(=O)c2ccc3[nH]cnc3c2)o1 +COc1ccc(NC(=O)NC2c3ccccc3CC2O)c(OC)c1 +COCCN1CCN(C(=O)Cc2ccc[nH]2)CC1 +Cc1ccc(F)cc1NC(=O)Cn1nnc(-c2ccco2)n1 +CCCn1nnnc1Cn1cnc(C2CCC2)cc1=O +Cc1ccc(C(=O)CCNc2ccccc2C)cc1N +Cc1nc(C)c(C(=O)OCC(=O)Nc2ccc(C)c(C)c2)s1 +CCCn1nc(-c2ccc(CC)c(N)c2)ccc1=O +Nc1ncc2ccoc2c1-c1ccccc1Br +CN(Cc1ccccc1)C(=O)c1cc(Cl)c2c(c1)OCCCO2 +CCCOC1CCCN(C(=O)Nc2cccc(CN(C)C(C)=O)c2)C1 +COc1cccc(-c2nc3ccc(Cl)cn3c2N)c1 +N#CC1(C(=O)NC2CC(=O)N(Cc3ccccc3)C2)CCCC1 +CC(=O)c1cc(C#N)cc(CNC(=O)OC(C)(C)C)c1 +O=C(NC1CCSc2ccc(F)cc21)c1ccc(Cl)cc1 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1ccno1 +CC(C)c1ccc(S(=O)(=O)NCCc2cnn(C)c2)cc1 +COc1cccc(NC(=O)c2nccc3c(N)ccc(F)c23)c1 +Cc1noc(C(C)OC(=O)C(C)(C)Oc2ccc(Cl)cc2)n1 +CN(C)C(=O)CN(C)S(=O)(=O)c1ccccc1Br +CC(=O)c1cccc(S(=O)(=O)NC2CCSc3ccccc32)c1 +COc1cc(C(N)c2nc3c(s2)CCC3)cc(O)c1OC +O=C(NCCN1CCOCC1)C1(c2ccc(F)cc2)CCOCC1 +CN(CCC(F)(F)F)C(=O)CCc1ccc(F)c(F)c1 +Cc1nn(C)cc1C(=O)Nc1cnn(CC(F)(F)F)c1 +CC1CCCCN1c1ncc(N)cc1Br +O=C(CCC1CCCO1)N1CCCC1c1nc2ccccc2[nH]1 +CCOC(=O)c1ccc(NCC(=O)N2CCCC2)cc1 +CCCN(Cc1ccccc1)C(=O)c1cnc2onc(C)c2c1 +CCCc1nc(COc2cccc(C(N)=O)c2)cs1 +CCOCC(=O)N(C)Cc1cc(Cl)cc(Cl)c1 +Cc1nc(C)n(-c2ccccc2NC(=O)N2CCCC2C2CCC2)n1 +COC(=O)c1cccc(N(C)c2ccc(N)c(F)c2)c1 +CC(C)COc1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1 +COc1ccc(C(C)Nc2ccc(CN3CCCC3=O)cc2)c(F)c1 +CCCC1CN(C(=O)c2ccc(C)c(OCC)c2)CCO1 +COc1ccc(OC)c(-n2nnc(C#N)c2-c2cccs2)c1 +CC(C)(C)c1nc2sc(C3CCCO3)nn2c1C#N +CC(=O)OC1(C(=O)N2CCOCC2)c2ccccc2-c2ccccc21 +CCCOC(=O)c1cc(-c2ccc(F)cc2)nn1C +C#CCOc1ccc(F)cc1NC(=O)c1ccc(-n2ccnn2)cc1 +Cc1ccc2ncc(CNc3ccc4c(c3)OCC(=O)N4)n2c1 +CCNC(=O)N(C)CCCc1n[nH]c(N)c1C#N +COc1ccccc1CC(=O)N1CCNCC1C(=O)N1CCOCC1 +CC1CC(C)CN(C(=O)Nc2ccccc2N2CCCC2=O)C1 +CC(C)(C)CC(=O)NCC(=O)NCc1ccccn1 +Cc1cc(Br)c2c(c1)C(CN(C)C)NCC2 +Cc1ccccc1OCCCC(=O)NC(C)C(N)=O +CCc1cc(=O)[nH]c(Cc2cc(F)cc(F)c2)n1 +CC(=O)c1ccc(NC(=O)c2cnn(-c3ccccc3F)c2)cc1 +Nc1nccnc1C(=O)N1CCC(NC(=O)c2ccccc2)CC1 +N#Cc1cccc(NC(=O)CCCCCNC(N)=O)c1 +O=C(Nc1cccc(N2CCNC2=O)c1)C1CCCCC1 +CC(C)Cc1nnc(NC(=O)COc2ccc3c(c2)OCO3)s1 +O=C(c1ccc(-c2ccco2)o1)N1CCc2ccccc2C1 +CC(=O)N1CCc2cc(C(=O)C(C)OC(=O)c3cccnc3)ccc21 +CCN(CC)C(=O)C(C)Sc1nnc(-c2ccncc2)o1 +COC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)c2ccc(O)cc2)c1C +O=C(c1ccc2c(c1)OCO2)N1CCC(c2ccsc2)CC1 +COc1c(F)cc(NC(=O)Nc2ccncc2)cc1F +COC(=O)c1cc2ccccc2cc1Oc1ccc2nnnn2n1 +CSc1nc(C)nc(C)c1C(=O)N(CC1CC1)CC1CC1 +CCCn1c(=O)c2c(nc(-n3nc(C)cc3C)n2C)n(C)c1=O +COc1cccc(CN2CC(C(=O)N3CCOCC3)CCC2=O)c1 +O=C(CCN1CCOCC1)Nc1ccccc1C(F)(F)F +CC(=O)Nc1ccc(NCCN2CCNC2=O)cc1 +COCCNC(=O)CCNC(=O)Nc1ccccc1Cl +COCCNC(=O)C(C)Sc1ccc(O)cc1 +CCC(C)N1CC(C(O)c2ccc(OC)c(OC)c2)CC1=O +COc1cc(C)c(NC(=O)N2CCCC(C)C2)cc1OC +Cc1ccc(-c2nc(CN3C(=O)COc4ccccc43)no2)cc1C +CCCn1nc(-c2ccc(C)cc2C)cc(CO)c1=O +N#Cc1cc(F)ccc1NC(=O)NCCc1nnc2n1CCCCC2 +CC(C)C(NC(=O)c1nc2ccccn2n1)C(=O)N1CCCCC1 +O=C(Cc1nc2ccccc2s1)c1ccccn1 +CCC(C)NC(=O)C12CC3CC(CC(NC(C)=O)(C3)C1)C2 +Cc1ccc2c(CC(=O)NC(C)c3nnc4ccccn34)coc2c1C +Cc1ccc(C(=O)Nc2ccc(SC(=O)N(C)C)cc2)cn1 +CCCC(C#N)CC(=O)N1CCN(c2ccccc2)CC1 +COc1ccc(CNc2nccc3c(N)cc(F)cc23)cc1 +CN(C)c1nc(N)nc(CN2CCc3ccc(Cl)cc3C2)n1 +C=CCOC1CN(C(=O)c2ccc(F)cc2)C2CCCOC12 +CC(=O)c1ccc(Nc2nnc(-c3ccccc3)c(=O)[nH]2)cc1 +Cc1ccccc1OCC(=O)Nc1ccc(C(N)=O)c(Cl)c1 +CC(=O)c1ccc(NC(=O)c2ccccc2F)cc1 +Cc1ccc(CN(C(=O)Cn2c(C)c(C)sc2=O)C(C)C)s1 +Cc1cc(C)n(-c2ccc(NC(=O)N3CCc4ccccc4C3)cn2)n1 +Cc1nc(-c2cccc(NC(=O)Cc3ccc[nH]3)c2)oc1C +CCN(C(=O)c1cc(C(N)=O)cs1)c1ccc(F)cc1 +COc1ccc(CNc2nccc(N3CCCC(O)C3)n2)cc1OC +COc1ccccc1-c1nc(NC(=O)c2cc(Cl)cn2C)n[nH]1 +CC(=O)Nc1cccc(Nc2ncnc3c2oc2ccccc23)c1 +Cc1noc(C2CCCN(C(=O)c3cc(C)sc3C)C2)n1 +Cc1ncc(CC(=O)NC(C)c2ccc3c(c2)CCCC3)c(=O)[nH]1 +CC(c1ccc(S(C)(=O)=O)cc1)n1c(=O)[nH]c2ccccc2c1=O +Cn1c(SCC(=O)C(C)(C)C)nnc1C(F)(F)F +COCCNC(=O)CNC(=O)c1ccc(Br)cc1Cl +OC1CCCN(c2ncnc3cc(F)c(F)cc23)C1 +CCOC(=O)CCC(C)NC(=O)c1cc(F)cc2[nH]cnc12 +O=C(NCC1CC1)N1CCN(c2cnccn2)CC1 +CCOC(=O)Nc1ccc(NCc2cnn(C)c2)cc1 +CCN(CC)C(=O)c1ccc(C(F)(F)F)nc1C +CC(=O)NC1CCCN(C(=O)Nc2ccccc2N(C)C)C1 +CCNC(=O)N1CCc2nc(C)nc(N3CCCC3)c2C1 +COc1ccc(OC)c(COC(=O)CNC(C)=O)c1 +CC(=O)Nc1ccc(CNCCc2ccc(-n3cccn3)cc2)cc1 +O=C(CCc1cccs1)NCc1ccccc1Cn1cncn1 +COCCNc1nc(-c2scnc2C(C)C)cs1 +NC(=O)c1cc(NC(=O)CCc2cccnc2)ccc1F +O=C(CC(F)(F)F)N1CCC2(CC1)CC(Oc1cccnc1)CO2 +O=C1NC(c2c[nH]nc2-c2ccc(F)cc2)Nc2ccc(Cl)cc21 +COC(=O)C(C)CN(C)Cc1cn(C)nc1-c1cccnc1 +Cc1nc(SCC(=O)Nc2ccccc2)[nH]c(=O)c1C +Cn1nc(NC(=O)Nc2ccccc2CO)c2ccccc2c1=O +Cc1csc(CNc2cccc(Cl)c2C)n1 +CC1CCC(C)N(C(=O)c2cccc(-c3ccoc3)c2)C1 +Cc1ccc(C)c(C(=O)N2CCC(NC(=O)c3ccccc3)CC2)c1 +CC(=O)Nc1cccc2c1CCN(S(=O)(=O)C(C)C)C2 +COCC(C)NC(=O)Nc1cccc(NC(C)=O)c1 +CCCS(=O)(=O)N(CCO)c1ccc(C)cc1C +Cc1ccc(NC(=O)N2CCNC(=O)C2)cc1F +CCS(=O)(=O)N1CCCc2cc(C(N)=O)ccc21 +C=CCNC(=O)CN1CCN(c2ccccc2)CC1 +CCn1nc(C)c(CCNC(=O)Nc2ccccc2Cl)c1C +Cn1ccc(NC(=O)CCn2c(=O)oc3cc(Cl)ccc32)n1 +Cc1ccc(OCCc2nc3scc(N)n3n2)cc1 +Cc1ccc(F)cc1NC(=O)c1cccc(C#N)c1 +O=C(COc1ccccc1)Nc1ccc(C(=O)N2CCOCC2)cc1 +CCOc1ncccc1C(=O)NCc1ccccc1F +CC(C)CNC(=O)CNC(=O)Nc1cccc(N2CCOCC2)c1 +Cc1cccnc1NC(=O)c1oc2c(c1C)C(=O)CC(C)(C)C2 +COC(=O)c1ccccc1NC(=O)N1CCOC(c2ccccc2)C1 +CCOC(=O)NCCC(=O)N1CCCCCC1c1cccn1C +CCCNC(=O)CCC(=O)c1cc(C)c(C)cc1OC +CC(=O)c1ccccc1OCC(=O)Nc1cccc(Br)c1 +CC(NC(C(=O)NC1CC1)c1ccccc1)c1ccccc1 +CCC(OC)C(=O)Nc1cnn(CC2CCCO2)c1 +Cc1noc(C)c1CCCNS(=O)(=O)N1CC(C)OCC1C +O=C(Cc1noc2ccccc12)NCc1ccc(OCC2CC2)nc1 +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1cccs1 +Cc1ccc(C(=O)Nc2ccc3c(c2)C(=O)NCCO3)cc1C +COc1ccc2nc(C(=O)NC3(C(N)=O)CCCCC3)ccc2c1 +COc1ccc(CCC(=O)Nc2nc(SC)ns2)cc1 +COc1cc(C)c(SCC(=O)NCc2ccccn2)cc1OC +O=C(NCc1ccccn1)c1ccc2c(c1)nc1n2CCOC1 +CCOC(=O)c1sc(Nc2cccc(C)n2)nc1C +Cc1nn(-c2ccccc2)c(C)c1NC(=O)CN1CC(C)OCC1C +COC(=O)c1ccc(CNC(=O)c2ccc3ccccc3n2)cc1 +O=C(Nc1ccn(CCc2ccncc2)n1)c1cscn1 +CCOC(=O)c1sc(NC(=O)c2cccc(OC(C)C)c2)nc1C +CCNC(=O)CSc1nnc(C2COc3ccccc3O2)n1C +Cc1cc(C(=O)OCc2nnc(C)o2)c2ccccc2n1 +Cc1cc(C)nc(N2CC(c3ccnc(C)n3)C2)n1 +CC(O)(CNC(=O)NCc1ccccc1)c1ccc2c(c1)OCO2 +Cc1csc(C(C)N(C)C(=O)c2c(-c3ccccc3)noc2C)n1 +COCCN(C1CCCC1)S(=O)(=O)c1cc(C)ccc1C +FC(F)(F)c1cc(Br)c2c(c1)CNCC2 +Cn1c(=O)cc(N(Cc2ccccc2)Cc2ccccc2)[nH]c1=O +O=C(CCc1ncc(-c2ccccc2)o1)NCCC1CCCO1 +Cn1cc(CCNC(=O)Nc2ccccc2Cl)c2cccnc21 +CC(=O)c1cc2c3c(c(=O)oc2c(C)c1O)CCCC3 +COc1ccc(Cl)cc1-n1nc(CO)c(=O)cc1C +CCc1nc(CC(=O)Nc2cc(Cl)ccc2C(N)=O)cs1 +CCCCCNC(=O)C1CCCN1C(=O)c1cccs1 +CCN(Cc1ccccc1)C(=O)Nc1ccc(Cl)c(C(=O)NC)c1 +CCc1nc(CC(=O)NCc2ccnn2C)cs1 +CCN(C(=O)CNc1ccc(C)cc1F)C1CC1 +Cn1nccc1-c1cccc(-c2nc3c(cc2C(N)=O)CCC3)c1 +COCC(=O)N1CCCN(c2cc(C3CC3)ncn2)CC1 +COC(=O)c1c(C)[nH]c(C(=O)Cn2c(=O)oc3ccccc32)c1C +COc1ccc2c(C)nn(CCO)c2c1Br +COc1ccccc1CCNC(=O)CSc1nccn1C +N#Cc1nnn(-c2ccc(O)cc2)c1-c1cccnc1 +CC(=O)c1ccc(Nc2ncnc(Nc3ncccc3C)c2N)cc1 +COc1ccccc1C(NC(=O)c1scnc1C)c1ccccn1 +O=S(=O)(c1cccnc1)N1CCc2ncncc2C1 +O=C(CSc1nnnn1C1CC1)N1CCC(CO)C1 +Cc1nn(C)c2ncc(S(=O)(=O)NCCCCC(C)C)cc12 +C#CCNC(=O)NCC(=O)Nc1c(C)cccc1C +CC(=O)NC(C)(C)c1cnnn1-c1nonc1N +Cc1ccc(S(C)(=O)=O)cc1NC(=O)c1ccc2ccccc2n1 +CC(C)COCC(C)NC(=O)c1cnc(C2CCCO2)s1 +Cc1nnc2sc(-c3ccc4c(c3)OCCO4)nn12 +COc1cccc(-c2nc3sc(C)nn3c2CO)c1 +Cc1ncc2c(=O)n(-c3ccccc3N)ccc2n1 +Cc1nc(CNC(=O)c2cc3cc(F)ccc3oc2=O)c(C)s1 +O=C(C(O)c1ccc(Cl)cc1)N1CCNCC1 +CCNC(=O)CSc1nnc(-c2ccccc2OC)n1C +CCOC(=O)Nc1ccc(C(=O)N(C)CC(C)C)cc1 +CCNC(=O)CSc1nnc(-c2ccccc2)n1N +CC(NC(=O)NCCN1CCOCC1)c1ccc(-n2cncn2)cc1 +COc1cccc2c(C)c(C(=O)Nc3nc(CC(N)=O)cs3)oc12 +Cc1cc(CNC(=O)Nc2cccc(Cl)c2)c(C)o1 +Cc1cc(C2CCCN2C(=O)C2COc3ccc(Cl)cc3C2)on1 +O=C(Cc1ccncc1)N1CCOC(CCc2ccccc2)C1 +COc1ccccc1OCC(C)NC(=O)C1CCC(F)(F)CC1 +CCc1noc(CC)c1CC(=O)Nc1cnccc1OC +Cn1cc(C(=O)Nc2cc(-c3c(F)cccc3F)[nH]n2)ccc1=O +CC(=O)Nc1cccc(NC(=O)CCn2cnc3ccccc32)c1C +CCOCC(=O)Nc1ccc(CC(=O)N(C)c2ccccc2)cc1 +O=C(CNC(=O)c1cccc(Br)c1)Nc1cccnc1 +O=C(NC(c1ccccc1F)C1CCCC1)c1ccc2nncn2c1 +CCc1ccc(S(=O)(=O)NCC2(CO)CC2)s1 +Cc1cc(OC(C)C)ccc1NC(=O)c1ccnc(-n2ccnc2)c1 +COCC12COCC1CN(S(=O)(=O)c1ccc(C)cc1OC)C2 +Cc1cc(-c2cnc(C)nc2-c2cccs2)on1 +CCCCS(=O)(=O)N1CCCC1C(=O)Nc1ccc(C)c(F)c1 +CCc1cccc(NC(=O)CC(NC(C)=O)c2ccc(OC)cc2)c1 +CC(OC(=O)c1ncn(-c2ccccc2)n1)c1ccc(C#N)cc1 +Cc1c(C(C)(C)O)cnn1-c1ccccc1Br +COc1ccc(S(=O)(=O)NC(C)c2ccc(C)cc2)cc1OC +CN(Cc1ccco1)C(=O)c1ccc(-c2ccccc2)[nH]c1=O +CCOc1ccc(C(=O)Nc2cc(-c3ccsc3)no2)cc1 +CC(C)(CNC(=O)N1CCCC1)N1CCOCC1 +Cc1[nH]n(CC(C)C)c(=O)c1C(=O)Nc1ccccc1Cl +CCNC(=O)COc1cc2c(cc1CO)OCO2 +CNC(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1 +CN(C)c1ccc(C(=O)NCCNC(=O)c2ccc(F)cc2)cc1 +COc1cc(C2CC(O)=Nc3c2cnn3Cc2ccccc2)ccc1O +CC(NC(=O)NCc1ccc(F)cc1)c1ccncc1 +O=C(Nc1cccc(-c2nnco2)c1)C1CCOC1 +CNc1snc(C)c1C(=O)N1CCN(Cc2cc(C)no2)CC1 +Cn1cc(CCC(=O)Nc2ccc3[nH]c(=O)sc3c2)cn1 +O=C(Cn1cnc2ccccc2c1=O)NCCc1cc(F)cc(F)c1 +COC1COC2(CCCN(C(=O)c3ccc(F)c(F)c3)C2)C1 +CCCC(=O)Nc1cccc(NC(=O)c2ccc(=O)n(C)c2)c1 +O=C(Nc1cc(F)ccc1F)c1ccc2ccccc2n1 +COC(=O)c1cccc(OCCSc2ccccn2)c1 +Cc1ccn(Cc2ncc(C(C)(C)C)o2)c(=O)c1C#N +CCOc1ccccc1CCC(=O)N1CCOC(C)(C)C1 +NC(c1nccs1)c1c2c(nc3ccccc13)CCCC2 +CN(C)C(=O)C(Cc1ccccc1)Nc1ncncc1Br +CCn1nc(C(=O)NCCc2ccc(C)c(OC)c2)ccc1=O +O=C(NCc1nc2ccccc2[nH]1)c1ccc(F)cc1F +CNc1ccc(C(=O)N2CCOC(COc3ccc(F)cc3)C2)cc1 +Cc1ccc(S(N)(=O)=O)cc1NCc1cnn(C)c1 +CCc1ncc(C(=O)N2CCN(Cc3ccccc3C#N)CC2)cn1 +COc1ccc(Br)cc1NC(C)c1ccccn1 +O=C(Cn1cc(C2CC2)nn1)N(c1cccc2cccnc12)C1CCC1 +COc1cc(C(=O)N(C)Cc2ccccc2)ccc1OC(C)C +CS(=O)(=O)NCC1CCCCN1C(=O)c1cc2c(s1)CCC2 +CCOc1ccc2c(=O)n(Cc3cccc(C#N)c3)ccc2c1 +COc1cc(OC)c(NC(=O)c2cccc3[nH]ccc23)cc1F +CC(C)N(C)C(=O)c1cc(COc2ccc3ncccc3c2)on1 +COc1ccccc1CCNC(=O)NCC(C)(C)c1ccncc1 +COc1ccc(CNC(=O)Cc2cc(-c3ccccc3)no2)cc1 +CN(C)S(=O)(=O)c1ccc(NCc2cn[nH]c2)cc1 +COc1cc(N2CC(C(=O)N(C)C)CC2=O)cc(OC)c1OC +CCC(=O)Nc1ccc(C(=O)C2CCCCN2)cc1 +O=C(Nc1ccc(-n2ccnc2)nc1)C1CC=CCC1 +CCn1cnnc1CNC(=O)NCc1nc2ccccc2s1 +COc1ccnc(Sc2nnc(-c3cccc(C)c3)n2C)n1 +Cc1ncsc1C(=O)N1CCCCCC1c1cccn1C +CN(Cc1nccs1)C(=O)Nc1ccccc1CN1CCOCC1 +Cn1c2ccccc2c2nnc(SC3CCCCC3=O)nc21 +CC(C)NC(=O)CC1(CC(=O)Nc2nccs2)CCCCC1 +Cc1cccc(CCC(=O)NCc2cc(C)oc2C)c1 +COC1CCCCC1NC(=O)c1scnc1C1CC1 +CC(=O)Nc1cccc(C(C)OC(=O)c2cn3ccc(C)cc3n2)c1 +COCC(=O)Nc1nn(-c2ccccc2Cl)cc1C +Cc1nccc(CNCc2cnn3ccccc23)n1 +COCCN(C)C(=O)Nc1ccccc1Oc1ccccc1 +O=c1oc2cccnc2n1CCc1ccccc1Cl +Cc1nn(C)c(C)c1CN(C)c1nc(N)nc2c1nc(C)n2C +O=C(Nc1ccncc1)NC1CCSc2ccccc21 +CCn1ccc(=O)n(Cc2cccc(Cl)c2)c1=O +COc1cccc(OC)c1OCc1cccnc1N +CCOC(=O)CNS(=O)(=O)c1ccc2c(c1)CCO2 +CNC(=O)c1cn(Cc2ccccn2)c2cccc(N)c2c1=O +Nc1cc(=O)[nH]c(Cc2cccc(Br)c2)n1 +Cc1ccc(C2N(c3cccc(Cl)c3)C(=O)C3CCCN32)o1 +CCN(CC(=O)NC)C(=O)c1ccc(F)cc1N +Cc1cc(C)n(CC(=O)NC2CCc3nnc(C)n3C2)n1 +COc1ccc(CC(=O)Nc2ccc3c(c2)COC3)c(Cl)c1 +Cc1cc(C)n(CC2CCCCN2C(=O)COCC2CC2)n1 +CNC(=O)C1CCCN1C(=O)Nc1cc(-c2ncco2)ccc1C +CN(CCc1ccccc1)C(=O)c1cncn1-c1ccccc1 +O=C(NCc1nc(-c2ccccc2)cs1)Nc1cccc(F)c1 +C#CCOc1ccc(C(=O)NCC2CN3CCCCC3CO2)cc1 +CCC(=O)NCC(=O)NCC1CCN(c2ccc(Cl)cc2)C1 +CC(C)(C)n1ncc2c1NC(=O)CC2c1cccc(F)c1 +O=C(NCC(=O)N1CCCC1)c1cccc2cn[nH]c12 +COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)C1CC1C +O=C1CN(Cc2cnc(-c3ccsc3)s2)C2CCCCC2N1 +COc1ccc(-c2nnc3sc(-c4ccsc4)nn23)cc1OC +CCCS(=O)(=O)N(C)c1ccc(NC)c(OC)c1 +Nc1cccc2c1N(CC(=O)NCC1CCCO1)CCO2 +CC(C)(C)OC(=O)CNC(=O)c1csc(-c2ccsc2)n1 +Cc1ccc(Nc2c(N)c(C)nn2C)c(Br)c1 +O=C(Nc1ccc2c(c1)CCC2)c1cccc(F)c1 +C#Cc1cccc(NC(=O)c2cc(S(=O)(=O)NCC)ccc2F)c1 +CCc1noc(C)c1C(=O)NCc1cccc(Cn2ccnc2)c1 +CCCc1nc(Cn2cccc(C(F)(F)F)c2=O)no1 +C=CCCCN(C)C(=O)c1cc(OC)c(OC)cc1C +Cc1nccn1-c1ccc(C(C)NC(=O)NCCC(O)C(C)C)cc1 +COc1ccc2ccn(Cc3ccc(OC)c(F)c3)c(=O)c2c1 +COc1ccc(OCC(=O)NC(C)C(C)C)cc1 +CC1CN(C(=O)CCCOc2ccc3c(c2)CCC(=O)N3)CC(C)O1 +CCN(CCO)C(=O)CCNC(=O)c1ccc(F)cc1Cl +CC(=O)N1CCc2cc(NC(=O)COc3ccccc3C#N)ccc21 +Nc1c(NCc2ccccc2)ncnc1N1CCCCCC1 +CCC1c2ccsc2CCN1C(=O)c1ccc(=O)n(CCOC)n1 +CN(C)C(=O)c1cnn(-c2ccccc2)c1-n1cccc1 +O=C(CCc1ccc(O)cc1)NCCc1ccccc1 +O=c1[nH]nc(CN2CCN(c3ccc(F)cc3)CC2)[nH]1 +Cc1ccc(CN(CCO)C(=O)Nc2nn(C(C)C)cc2C#N)cc1 +Cc1cc(C)cc(OCCC(=O)N2CCOCC2C2CC2)c1 +CNC(=O)CCNS(=O)(=O)N(C)C1CCCCC1 +CN(C)c1ccc(C(=O)N2CCC(c3n[nH]c(C4CC4)n3)CC2)cc1 +CCS(=O)(=O)N1CCc2onc(COc3cccnc3)c2C1 +Cc1nc(-c2cccc(NC(=O)c3scnc3C3CC3)c2)oc1C +CCOc1ccc(N2C(=O)C(C)CS2(=O)=O)cc1 +CN(C)C(=O)c1nc(S(N)(=O)=O)ccc1OC1CC1 +CCCOc1ccc(-c2nc(C3CCOC3)no2)cc1 +Cc1noc(COCC(=O)NCc2cscn2)n1 +OCCCc1csc(COc2ccc3ccccc3c2)n1 +COc1ccc(CNS(=O)(=O)c2ccc(C#N)cc2)cc1F +CC(C)n1ncc2c1NC(=O)CC2c1ccccc1F +CC(=O)c1ccc(OCC(=O)Nc2ccccc2C(=O)C(C)C)cc1 +CC(C)(C)OC(=O)N1CCCC1C(=O)N(CCO)Cc1ccccc1 +O=C1OCCN1c1ccc(NCc2cc3cc(F)ccc3o2)cc1 +Cc1cnn(C2CCCN(C(=O)c3cc4ccccc4[nH]c3=O)C2)c1 +CCC(C)C(C)NC(=O)c1cc(Br)cnc1NC +CC(C)CNS(=O)(=O)c1ccc(CC(C)C)cc1 +O=C(Cn1nnnc1-c1ccc(Br)cc1)c1ccccc1 +CCc1c(C)sc(NC(=O)c2cccnc2)c1C#N +Cc1occc1C(=O)N1CCN(c2ccc(Cl)c(Cl)c2)CC1 +CCC(=O)N1CCCN(C(=O)Nc2cc(F)c(OC)c(F)c2)CC1 +CCOCCOC(=O)c1ccc(NC(C)=O)cc1 +N#Cc1ccc(-c2csc(N3CCCC3=O)n2)cc1 +CCc1cc(C(=O)Nc2n[nH]c(Cc3cccc(F)c3)n2)[nH]n1 +CCCCS(=O)c1nc2nc(C)c(Br)cc2s1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)CNC(=O)C1CCCC1 +CC(=O)NCCC(=O)Nc1c2c(nn1C)CCC2 +Oc1c(Cl)cc(Cl)c2c1CCNC2c1ccoc1 +CS(=O)(=O)Nc1ccc(C(=O)NCc2ccc(Cl)cc2)cc1 +CS(=O)(=O)N1CCCC(NC(=O)c2ccsc2)C1 +COc1ccc(-c2nnc(SCc3csc(C)n3)n2C)cc1 +NC(=O)CN1C(=O)COc2cc(NCc3ccccc3F)ccc21 +CC(C)CC(=O)Nc1nn2c(-c3cccs3)nnc2s1 +COc1cccc2c1C(C1CCCN1C(C)=O)NCC2 +CCC(=O)N(CC)Cc1cc(-c2ccc(OC)cc2)on1 +COC(=O)CCCN1C(=O)CNc2cc(C)ccc21 +O=C(Nc1ccccc1N1CCOCC1)c1ccc2nccnc2c1 +c1nc(C2CC2)sc1CN1CCOCC12CCC2 +CC(C)CC(CNC(=O)c1ccncc1)N1CCOCC1 +CN(Cc1cnn(C)c1)C(=O)NCC1CCOC1 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1cccs1 +Cc1nn(C)c2nc(N3CCCC3C(N)=O)sc12 +CC(C#N)Sc1nnc(SC(C)C#N)s1 +CCCc1ccc(C(=O)C2CCCN2C(C)=O)cc1 +Cc1nc(CCNC(=O)c2cnc3c(cnn3C(C)C)c2)cs1 +N#CCOc1cccc(CC(=O)N2CCC(C3CCOCC3)CC2)c1 +CCCNC(=O)Cn1cc(CO)c2cccc(C)c21 +CC(C)(CNC(=O)c1csc(-c2ccco2)n1)c1ccncc1 +Cc1nc(-c2ccc3c(c2)CCN3C(=O)c2c(C)noc2C)cs1 +COc1ccc(S(=O)(=O)NCC2COC3(CCCC3)O2)cc1F +COc1ccc(OC)c2c1CN(CCCCCO)CC2O +O=S(=O)(c1ccc(F)c(F)c1)N1CCCC(CO)C1 +CCCc1nc2cc(Cl)cnc2n1CC(C)C#N +Cc1cc(CNc2cnn(CC(F)(F)F)c2)ccc1F +O=C(NC1(c2nc(-c3cccnc3)no2)CCCCC1)c1ccco1 +CC1CCC(C(N)=O)CN1C(=O)c1cnc(-c2ccccc2)nc1 +CCn1ccc(C(=O)N2CCCC(c3nc4c(C)cccc4[nH]3)C2)n1 +c1ccc(-c2noc(C3CCCCN3Cc3cc[nH]n3)n2)cc1 +O=C(CCc1cccnc1)NC1CCc2ccccc21 +CCOc1ccc2ccccc2c1C(=O)CCC(=O)OC +Cc1ccc(CNC(=O)CCCc2c[nH]c3ccccc23)n1C +CC(Cc1cccs1)NC(=O)CNC(=O)c1cc(F)cc(F)c1 +CCc1ocnc1C(=O)N1CCCCC1c1nccs1 +COCCc1noc(CN2CCc3ccc(Br)cc32)n1 +CN1CCN(C(=O)CNc2nc3ccccc3s2)CC1 +CN1CCN(Cc2cc(Br)cs2)C(=O)C1=O +Cn1cc(CN2CCN3C(=O)N(Cc4ccccn4)CC3C2)cn1 +Cc1nc2c(Cl)cc(Br)cn2c1N +CCCCNC(=O)CSc1nnc(-c2cccs2)[nH]1 +Cc1cc(C(=O)c2ccc(N3CCOCC3)o2)ccc1F +Cc1sc2ccccc2c1S(=O)(=O)NCc1ccc(C#N)cc1 +Cc1ccccc1OCC(=O)NCC1(N2CCOCC2)CCCCC1 +COc1ccc2nc(C(C)N3CC(C)OC(C)C3)[nH]c2c1 +Cc1nc(C)n(CC(=O)Nc2ccc(C)c(Cl)c2)n1 +CCc1ncc2c(n1)CN(C(=O)COCC1CCCCO1)C2 +c1ccc(Cc2noc(CN3CCOC(c4nccs4)C3)n2)cc1 +CC1CC(=O)N(C)c2cc(C(F)(F)F)cc(N)c2O1 +CCCCC1C(=O)N(C)CCN1C(=O)c1ccc(-c2cc[nH]n2)cc1 +CC1CNC(=O)c2cc(Oc3ccccc3)ccc21 +CC(Cc1ccccc1F)C(=O)NCc1cc(C(C)C)no1 +CSc1nnc(NC(=O)c2ccc(Cn3ccnc3)cc2)s1 +N#CCCN(C(=O)Cc1ccccc1N)c1ccccc1 +N#Cc1sc2nccc(Nc3ccccc3)c2c1N +CNC(=O)c1cccc(OC(=O)Cn2c(C)c(C)sc2=O)c1 +Brc1cccc(C2CCc3conc3N2)c1 +CC(C)c1nncn1CCNC(=O)Cc1ccc[nH]1 +COCCOc1ccccc1C(=O)N(C)Cc1cccnc1 +O=C(CC1CCCCC1)Nc1ccc2c(c1)NC(=O)CO2 +CC(C)NC(=O)CCOc1ccc(N)cc1Cl +OCc1nc2ccccc2n1Cc1ccc(Br)cc1F +CC(C)(NCC(=O)NCc1cccnc1)c1cccc(F)c1 +CN(CC(=O)NCc1ccccn1)c1nnc(N2CCCC2=O)s1 +CCCN(C)C(=O)c1ccc(OCC(F)F)nc1 +Fc1ccc(C2CC(C(F)(F)Cl)n3nccc3N2)cc1 +NC(=O)Cc1cccc(OC(=O)c2cc3cc(F)ccc3[nH]2)c1 +CC(=O)c1cc2cc(C(=O)Nc3ccc4c(c3)OCO4)cnc2[nH]1 +CS(=O)(=O)N(CC(=O)NC1CCCC1)c1ccc(F)c(Cl)c1 +Cc1nn(C)c2nc(N3CCCC(C(=O)c4ccccn4)C3)sc12 +CCOC(=O)CCN1CCN(Cc2ccccc2)C(=O)C1=O +Nc1nc2c(ncn2S(=O)(=O)c2ccc(Cl)cc2)c(=O)[nH]1 +CNc1snc(C)c1C(=O)N(C)Cc1cc(Cl)ccc1OC +Cc1csc(=O)n1CCC(=O)N(C)Cc1ccc(C(N)=O)cc1 +CC(C)(CCCO)CNC(=O)Nc1ccc2c(c1)CCC2 +C#CCNC(=O)CSc1nnc(-c2ccoc2C)n1CC=C +Cc1csc(NC(=O)c2cc(F)c(F)cc2Cl)n1 +Cc1cn2c(C3NC(N)=Nc4nc5ccccc5n43)c(C)nc2s1 +Cc1ccc(O)cc1NCc1ccc(F)c(C#N)c1 +C=CCNC(=O)c1ccc(OCc2c(C)noc2C)cc1 +CN(C)C(=O)c1ccc2c(c1)N(C)C(CC(=O)NC1(CO)CC1)CO2 +Cc1cc(C)c(-c2cc(CO)nn2CC(O)CO)c(C)c1 +COc1ccc(-n2cnc(=O)c3ccccc32)cc1N +COc1ccc(-c2c(-c3ccccc3)n[nH]c2N)cc1 +CC(=O)Nc1cccc(NC(=O)c2n[nH]cc2N)c1 +CC(C)CNC(=O)c1cn(C2CCCC2)c2cccc(N)c2c1=O +COc1cccc2c1OCC(CO)C2N(C)C(=O)Nc1ccccc1 +c1ccc(OCc2nc(-c3ccsc3)no2)cc1 +COC(=O)c1ccc2c(cnn2CC(F)(F)F)c1 +CC(C)(C)CC(=O)NCCNC(=O)c1ccnc2c1OCO2 +COc1ccc(CNc2ccc(CN3CCCC3=O)cc2)cc1OC +COc1ccc(OC)c(NC(=O)CC(C)(C)C)c1 +CCOc1ccccc1CNC(=O)Nc1nc(C)cs1 +Cc1cc(C(F)(F)F)nn1CC(=O)Nc1cnc2ccccc2c1 +CCOc1ccc(F)c(C(=O)NC(C)c2cnn(C)c2)c1F +CC(O)(CC(=O)N1CCN(Cc2cccs2)CC1)c1ccccc1 +CC(C)n1nc(-c2cccc(F)c2)c2c1CCNC2 +COc1cccc(OCCNC(=O)c2cccs2)c1 +Cc1ccc(-n2c(C)c3c(C)nnc(C)c3c2C)cc1 +Cc1ccc(CNC(=O)c2cc3c(CO)cnc(C)c3oc2=O)cc1 +COc1ccc(C(=O)CC2(O)C(=O)Nc3c2ccc(Cl)c3C)cc1 +Cc1cc(Cl)ccc1NC(=O)Oc1ccncc1 +Cc1noc(C2CN(C(=O)c3ccccc3C)C2)n1 +CC1CN(C(=O)Nc2cccc(N(C)C)n2)CC(c2ccsc2)O1 +Cc1ncc(C(=O)N2CCN(C(C)c3ccccc3F)CC2)s1 +COc1ccc(NC(=O)C(NC(=O)c2cccc(C)c2)C(C)C)cn1 +CN(Cc1cnccn1)C(=O)c1cn(C2CCCCCC2)nn1 +Cc1cccc(CC(=O)N2CCC(c3cc(C)n[nH]3)CC2)c1 +CNC(=O)N1CCCN(C(=O)c2cccs2)CC1 +Cc1csc(CCNCc2ccc(Br)cc2F)n1 +O=C1NCCN(C(=O)c2cnns2)C1c1ccccc1Cl +CC(C)n1cnnc1CNCc1cccc(OC2CCCC2)c1 +O=c1nc2n3cc(C(F)(F)F)cc(Cl)c3ncc-2s1 +Cc1ccc2nc(COc3ccc(Cl)cc3)oc2n1 +CCCNc1ncc(Br)cc1C(=O)N1CCC(O)C1 +CCc1noc(COc2cccc(NC(=O)c3ccccc3)c2)n1 +CN1CC(C(=O)N(Cc2ccccc2)c2ccccc2)CC1=O +CC(=O)c1ccc2c(c1)N(C(=O)C(C)C)CC(C)O2 +Cc1ccc(-c2ccc(C(=O)N3Cc4cncnc4C3)cc2)cc1 +O=C(NC(C1CC1)C1CC1)C1CC(=O)N(Cc2ccccn2)C1 +CCc1cccc(C)c1NC(=O)COc1ccc(-c2nnco2)cc1 +O=S(=O)(NCCc1nncn1C1CC1)N1CCc2ccccc2C1 +O=C(NCCc1nc(-c2ccncc2)n[nH]1)Nc1cccc(Cl)c1 +O=C(NC1CCCOc2ccccc21)C1CC=CC1 +Cc1ccccc1OCCSc1nnc(-c2cccnc2)n1N +COc1cc(C)cc2c(=O)ccn(CCC(N)=O)c12 +CCOc1ccccc1CNS(=O)(=O)C(C)C +Cc1nccnc1C1CCCN1S(=O)(=O)c1cn(C)cn1 +Cc1ccc(CNS(=O)(=O)c2cccc(F)c2F)cn1 +CC(=O)N1CCN(C(=O)CNC(=O)c2ccc(C)s2)CC1 +Nc1ccccc1CCC(=O)Nc1ccc(F)c(F)c1F +Cc1ccn2c(=NC(=O)CSc3nncs3)[nH]nc2c1 +Cc1ccc(-n2c(SCCC#N)nnc2-c2ccncc2)cc1C +CNC(=O)c1ccc(=O)n(CC(=O)NCC(C)C)c1 +COc1ccc(NC(=O)NCc2ncoc2C)cc1-n1nnnc1C +CCSc1cccc(C(=O)Nc2nccs2)c1 +N#Cc1ccc(S(=O)(=O)Nc2ccsc2C(N)=O)cc1 +Cc1cc(CC(=O)NCC2CCC(C)(C)CC2)n[nH]1 +O=C(CC(c1ccccc1)c1ccco1)N1CCOCC1 +COc1ccc(CC(=O)Nc2cc(C)nn2C)cc1C +Cc1ccccc1OCC(=O)NCc1cscn1 +CCC(=O)N(Cc1cc2ccc(C)cc2[nH]c1=O)c1ccc(C)cc1 +COc1ccc(CC(C)C(=O)Nc2ccnc(N(C)C)n2)cc1 +COC(=O)c1cc(NC(=O)N2CC(C)CCC2C)ccc1C +CCC(NC(=O)Nc1ccc(F)c(F)c1F)c1ccc(OC)cc1 +Cc1cc(C(=O)Nc2cc(F)ccc2F)c2c(C)nn(C(C)C)c2n1 +CCOC(=O)CN(C(=O)c1cccnc1OC)C(C)C +CCn1c(CNCc2ccccc2OC)nc2ccccc21 +COc1ccc(CNCCc2cc(F)cc3c2OCOC3)cc1OC +O=C(Cn1nc2n(c1=O)CCCCC2)N1CCCC2CCCC21 +Cc1csc(CCNC(=O)N(Cc2ccccn2)C2CC2)n1 +CC1COCCN1c1nc2c(s1)C(O)CC(C)(C)C2 +Cc1nc(CC(=O)NC(C)c2ccc3c(c2)CCC(=O)N3)cs1 +Clc1ccc2ncnc(NCc3ccc4c(c3)OCO4)c2c1 +Cc1c(O)ccc(C(O)COc2ccc(F)cc2)c1O +COC(=O)NCc1cc(C2CC2)n(C2CCCC2)n1 +COc1ccc(C(=O)Nc2ccnn2C2CCCCC2)nn1 +CC(=O)c1c(OC(=O)Cc2ccccc2)ccc2c(C)cc(=O)oc12 +COc1ccc(Cc2nc(-c3cccnc3)n[nH]2)cc1C +CC1CN(c2nncc(-c3cccc(F)c3)n2)CC(C)O1 +CN(C)C(=O)N1CCC(C(=O)N(C)CCc2ccccc2)CC1 +CN(Cc1ccncc1)S(=O)(=O)C1CN(C(=O)C2CCCC2)C1 +C#CCN1CCN(C(=O)NC2CCc3nc(COC)nn3C2)CC1 +O=C(NCC(F)(F)F)c1cncc(Br)c1 +O=C(NC1CCCNC1=O)C1CN(C(=O)c2cccnc2)CCN1 +COc1cccc(C(=O)Nc2cccc(OCC(=O)N(C)C)c2)c1F +Cc1cc(C)n(CCCNC(=O)CCn2ncc3c(C)cccc32)n1 +NC(=O)CN1CCN(C(=O)c2cccc(-c3ccoc3)c2)CC1 +CCCn1c(NC(=O)c2nn(CC)cc2Cl)nc2ccccc21 +Cc1cc(Br)ccc1NC(=O)c1ccc(F)nc1 +Cn1nccc1NC(=O)CCCc1cc(F)ccc1F +Cc1cc(NC(=O)c2cc(C)n(Cc3ccccc3)c2C)n(C)n1 +COC(=O)N(C)c1ccc(Nc2nnc(C)c(C)c2C#N)cc1 +CN(C)c1ccc2oc(C(=O)Nc3ccccc3F)nc2c1 +Cc1cc(C)c2c(c1)CCNC2c1ccc(F)cn1 +C=CCN1CCN(C(=O)Nc2ccc(OC)cc2)c2cccnc21 +CCCC(=O)N1CCC(C(=O)OCc2ccc(F)cc2)CC1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)N1CCCC1C1CCCC1 +CCn1c(N)c(NCC(F)(F)F)c(=O)[nH]c1=O +CN(Cc1ccncc1)C(=O)Nc1ccc(OCC(F)(F)F)nc1 +Cc1cccc(-n2nnnc2SCC(=O)NCc2ccccc2)c1 +CN(C(=O)CNC(=O)c1cc2c(s1)CCCC2)c1nccs1 +CC(Sc1nc2ccccc2[nH]1)C(=O)Nc1cccc(C(N)=O)c1 +Cc1nc(C2CCCN(C(=O)c3ccnc(C4CC4)n3)C2)sc1C +Cc1cc(Oc2ncccn2)ccc1NC(=O)NCC1CCCO1 +COc1cccc(C(=O)NC(C)Cc2ccccc2F)c1F +COc1ccc(S(=O)(=O)Cc2nc(-c3ccccc3)no2)cc1 +Cc1nc(C(=O)Nc2ccc(-n3ccnc3)nc2)cs1 +CCCC1CN(C(=O)c2c(-c3ccccc3Cl)noc2C)CCO1 +COc1ccc(OCCNC(=O)NCc2ccc(C#N)cc2F)cc1 +Cc1cc2c(cc1NC(=O)c1ccccc1Cl)n(C)c(=O)n2C +CC(=O)c1c(C)cc(C)c(Cn2nc(-c3ccco3)oc2=O)c1C +Cc1nc2ccccc2c(=O)n1CCCC(=O)N1CCC(C(N)=O)C1 +O=C(COc1ccccc1)NCCc1ncc2ccccn12 +CCCCC(=O)Nc1nc2c(s1)CN(S(=O)(=O)C(C)C)CC2 +Cc1nc(Nc2ncnc(NCCC(C)C)c2N)sc1C +N#Cc1ccc(OCCN2CCOCC2C2CC2)cc1 +Cn1nc2n(c1=O)CCN(CCCc1nc(-c3cccs3)no1)C2 +CCCC(C)C(=O)Nn1c(C)nc2sccc2c1=O +COc1cccc2c1ccn2CC(=O)NCCn1cnc2ccccc21 +CC(C)N(CC(F)(F)F)C(=O)COc1ccc2ccc(=O)oc2c1 +Cc1cc(C)n(-c2ccc(C(=O)NCc3cnn4cccnc34)cc2)n1 +CSc1ncccc1C(=O)Nc1c(C)cccc1C +CCNc1nc(-n2ncc(C#N)c2N)c(Cl)cc1C(F)(F)F +CC(O)(CNC(=O)c1cccc(-c2ccoc2)c1)c1cccs1 +Nc1cnccc1NC(=O)COc1ccc(Cl)cc1 +Cn1nccc1CNC(=O)NCCN1CCOCC1 +Cc1ccc(CN2CC(C(=O)Nc3c(F)cccc3F)CC2=O)cc1 +CC(=O)Nc1nc(C(=O)Nc2ncc(C(C)C)s2)cs1 +CCCCOc1ccc(C(=O)Nc2cnn(C3CCOCC3)c2)cc1 +CCN(CC)C(=O)Nc1ccccc1C(=O)NCc1ccc(C)cc1 +O=C(NCCOc1ccccc1)C1CN(C(=O)c2cccs2)C1 +Cc1ccc(CC(=O)NCC(O)c2ccccc2Cl)cn1 +Cn1cc(NC(=O)NCCNc2nc3ccccc3s2)cn1 +CCOCCC(=O)Nc1ccc(OC)cc1Cl +Cc1nn(C)c2oc(N)c(-c3nc4ccccc4s3)c12 +COc1cccc(CCC(=O)NCc2ccccc2F)c1OC +Cc1nc(CNc2ccc(C)c(N3CCOC3=O)c2)cs1 +COCc1cc(C(=O)NCc2ccc(-c3ccc(O)cc3)cc2)no1 +COc1ccccc1-c1nc2ccccc2c(=O)o1 +O=C1NCC(c2ccc(F)cc2)N1c1ccc(F)cc1 +COc1cccc(COCC(=O)N2CCN(S(C)(=O)=O)CC2)c1 +CCOC(=O)CCC(=O)Nc1cc(Br)ccc1OC +CNC(=O)c1ccc(=O)n(Cc2c(C)cc(C)c(C(C)=O)c2C)c1 +O=C(Oc1ccc2c(=O)c(Cl)coc2c1)c1cccnc1 +CC(C)Cn1ncc(C(=O)Nc2cccc3[nH]cnc23)c1C1CC1 +CCN(Cc1cccs1)C(=O)NCc1nnc2n1CCC2 +Cc1cc(C(=O)N(C)C(C)c2cc(F)ccc2F)no1 +C=CCNC(=O)c1ccc(NC(=O)c2cc(-c3cccnc3)on2)cc1 +N#CCCc1cc(Cl)c(CCC#N)cc1Cl +COc1ccc(CCc2cccc(OC)c2C(N)=O)cc1 +CCCCNC(=O)CCNC(=O)c1cccs1 +Cc1cc(C)c(NC(=O)COn2nnc3ccccc32)c(C)c1 +O=C(NCC1CCOC1)Nc1ccc(Oc2cccc(F)c2)nc1 +O=C(NC1CCCOc2ccccc21)C1CCCC1 +Cc1ccc(CNC(=O)c2cnc(N3CCCC3)nc2C)o1 +N#Cc1ccc(-c2noc(Cc3coc(-c4ccccc4)n3)n2)nc1 +CCC(=O)Nc1nnc(Cc2ccc(S(C)(=O)=O)cc2)o1 +COc1ccc(OC)c(C(C#N)NC(=O)c2ccco2)c1 +Cc1cccc(C(=O)NCCC(=O)Nc2cc(C)ccc2C)c1 +O=C(NCC#CCOc1cccnc1)c1ccc2c(c1)OCO2 +Cc1c(-c2nc(-c3ccc4c(c3)OCO4)no2)nnn1-c1ccccc1 +COC(=O)C1CCCN1Cc1ccn(-c2cccc(F)c2)n1 +CC(CNC(=O)c1ccccc1O)CN1CCCC1=O +CS(=O)(=O)NCC1CCCN(C(=O)c2cc3ccccc3o2)C1 +Cc1c(C(=O)NCc2coc(-c3ccccc3)n2)cnc2ccnn12 +Cc1cc(Br)ccc1C1CCCC(=O)C1 +CCCNC(=O)CN1CCN(c2cc(OC)ccc2OC)C1=O +COc1cccn2c(C#N)c(-c3ccncc3)nc12 +CNC(=O)C1CCCCN1C(=O)c1ccc(C)c(F)c1 +O=C(CCc1nc(-c2ccco2)no1)NCCC1CC2CCC1C2 +Cc1nn(C)c2ncc(NC(=O)CCc3ccco3)cc12 +CCc1noc(CC)c1CNC(=O)c1ccn(-c2cccc(F)c2)n1 +COc1ccccc1Oc1ccc(C(=O)N2CCOCC2)o1 +Cc1nc(C)c(CC(=O)Nc2cccc(OC(F)F)c2)c(=O)[nH]1 +O=C1CCCc2cc(S(=O)(=O)NCc3ccc(F)cc3)ccc2N1 +COc1ccc(NC(=O)c2ccon2)cc1N1CCCCC1=O +CN(Cc1ccccc1-c1ccccc1)C(=O)NCc1ncn(C)n1 +Cc1cc(C)c(CNC(=O)C2(CC(=O)NC(C)C)CCCC2)c(=O)[nH]1 +CNC(=O)C1CCCN1c1nn2cc(C(C)(C)C)nc2s1 +CCOc1ccc(-c2cnn(CC)c(=O)c2CO)cc1 +O=C(CC1CCCC1)N1CCC(c2nnc(-c3ccco3)s2)CC1 +COc1cc(C)ccc1NC(=O)CCc1ccsc1 +COc1ccc(CNS(=O)(=O)c2ccccc2OC)cc1 +CNC(=O)CSc1nc(C)nc2sc(C)c(C)c12 +Cc1cc(CNC(=O)CC(c2ccccc2)C(F)(F)F)c(C)o1 +COc1cc(CNC(=O)c2cnns2)ccc1OCC(F)(F)F +Cc1noc(-c2sc3ncn(C)c(=O)c3c2C)n1 +CC(=O)NC1C(=O)N(CCc2ccccc2)c2ccc(F)cc21 +CCc1sc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)cc1C +O=C1CCCCCN1Cc1ccc(C(F)(F)F)c(F)c1 +CCC1C(=O)Nc2c1cc(C)cc2C(O)c1ccc(F)cc1 +CC(C(=O)N1CCCc2cc(OC(F)(F)F)ccc21)n1cccn1 +Cc1noc(NC(=O)COCCOc2ccccc2)n1 +CC(NC(=O)CNC(N)=O)c1ccc(Cl)cc1Cl +Cn1c(C(=O)Nc2cccnc2)cc2cc(F)ccc21 +COc1ccccc1N1CCN(C(=O)NC(C)c2nncn2C)CC1 +CCOC(=O)N1CCC(NC(=O)c2nc(-c3cnccn3)no2)CC1 +CCCCS(=O)(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 +CN(C(=O)Cn1cc(C2CC2)nn1)C(c1ccc(F)cc1)C1CC1 +CCNC(=O)c1ccc(NCC(=O)Nc2ccc(C)cc2)cc1 +COC(=O)C1CN(Cc2c(C)nn(CCO)c2C)CCO1 +Cc1ccc2onc(CNC(=O)NC(C)CCc3ccco3)c2c1 +Cn1ncc2c(NCC(O)c3cccnc3)nc(C(C)(C)C)nc21 +CCc1nc(CS(=O)(=O)c2ccc(C)cc2)sc1C#N +Cc1cc(Nc2cccc(Cn3cccn3)c2)nc(C)n1 +CC1CN(C(=O)OC(C)(C)C)CCN1c1ncccc1O +COC(=O)C(C)CN(C)C(=O)c1cc(Br)cn1C(C)C +CC(CC(=O)N1CCN(c2cnccn2)CC1)c1ccc(F)cc1 +COc1ccc(S(=O)(=O)N(C)CCc2ccccn2)cc1OC +Cc1cc(NC(=O)COc2ccc(-n3cnnn3)cc2)no1 +Cc1ccnc(NC(=O)C2COc3ccc(Cl)cc3C2)n1 +Cc1cc(Nc2ccc3c(c2)OCCO3)nc(-n2nc(C)cc2C)n1 +Cc1ccc(N)cc1NC(=O)c1cc(F)ccc1F +CCOC(=O)C(C)NC(=O)C1CC1c1ccccc1Cl +Cc1cc(CS(=O)(=O)N(C)CCOc2ccc(F)cc2)no1 +COc1cc(C)sc1C(=O)NCc1ccc2c(c1)OCO2 +Cc1cnn(-c2ccccc2)c1NC(=O)Cc1ccc(F)c(F)c1 +Cc1n[nH]c(-c2ccc(S(=O)(=O)NC(C)C)o2)c1C +O=S(=O)(Nc1ccc(F)c(F)c1F)c1ccc2c(c1)CCC2 +COc1cccc(C(C)Sc2n[nH]c(N)n2)c1 +O=C(Nc1ccccc1C(=O)OCC1CCCO1)c1ccco1 +CCn1c(SC(C)c2ccncc2)nnc1N1CCOCC1 +CCCOc1ccc(Cl)cc1S(=O)(=O)Nc1cccnc1 +Cc1noc(CCC(=O)NCc2ccnc(OC(C)(C)C)c2)n1 +CC(=O)OCCSc1nc(N(C)C)nc(N(C)C)n1 +Cc1cc(F)ccc1NC(=O)NCc1nnc2ccccn12 +O=C(NCc1ccncc1)Nc1cccc(OCCc2ccccc2)c1 +Nc1c(Br)cccc1C(=O)N1CCCC1 +CC(C)COC1CCN(C(=O)c2cncc(Br)c2)CC1 +CC(C)(C)c1ccc(S(=O)(=O)CCc2ccncc2)cc1 +CCOC(C)c1noc(CS(=O)(=O)c2ccc(C)cc2)n1 +O=C1OCCC1Sc1nccn1-c1ccc(Br)cc1 +CN(CCC#N)C(=O)Nc1c(F)cc(F)cc1-c1ccccc1 +COc1ccc2cc(C(=O)N=c3[nH]ccn3Cc3ccccc3)[nH]c2c1 +CC(C)N(C)c1cccc(NC(=O)NCC(=O)NCC(F)(F)F)c1 +CC(C)c1nc(CN2CCOCC2)sc1C#N +CC(CN(C)C(=O)c1ccccc1-c1cncnc1)c1ccccc1 +Cc1cccc(OCc2nnc(SCC3(CO)COC3)o2)c1 +CC1Cc2ccccc2N1C(=O)NCc1ccc(N2CCCC2=O)cc1 +COC(=O)CNC(=O)OCC1c2ccccc2-c2ccccc21 +CCOC(CC)C(=O)NCC1(c2ccccc2C)CCOCC1 +COC(=O)CCCCCc1nc2ccccc2nc1C +CCCN(C)S(=O)(=O)c1cc(C)c(C)cc1N +COc1ccc(S(=O)(=O)NCCC(N)=O)cc1C +Nc1cc2c(cc1NC(=O)NC1CCCCC1)OCCO2 +CCCn1nccc1NC(=O)CNC(=O)Cc1cccc(F)c1 +Cc1ccc(NS(=O)(=O)c2cccc3cccnc23)cc1F +CCc1cccc(OCc2nc(COC)c(C(C)=O)s2)c1 +COc1cccc(-c2c(C)cn(C)c(=O)c2C#N)c1 +COCCN1CCN(S(=O)(=O)CC(C)c2ccccc2)CC1=O +CCn1nccc1CN(C)S(=O)(=O)c1ccc(C)c(C)c1 +CC(=O)Nc1cccc(Nc2cc(=O)n(C(C)(C)C)c(=O)[nH]2)c1 +COc1cccc(C(=O)CSc2nnc(C)n2N)c1 +CC(=O)Nc1cccc(CNC(=O)Nc2nnc(C(C)(C)C)s2)c1 +COC(=O)N1CCC(NC(=O)c2cc(C)ccc2C)CC1 +O=C1COC2(CCN(C(=O)c3cccnc3)CC2)CN1CC1CC1 +CCN(CC)S(=O)(=O)N1CCCC1c1ccncc1 +O=C(NCc1ccccn1)c1ccc(Oc2ccc(F)cc2)cc1 +CCNC(=O)C(C)NCc1ccc(OC)cc1OC +Cc1nn(C)c(C)c1NC(=O)c1cccc(C#N)c1 +Cc1ccc(C)n1-c1c(C(=O)OCc2nc3ccccc3[nH]2)cnn1C +Cc1csc(NC(=O)CSc2cccc(C(F)(F)F)c2)n1 +Cc1onc(-c2cccc(Br)c2)c1C(=O)NC1CC1 +O=c1cc[nH]cc1NCc1ccc(C(F)(F)F)cc1 +Cn1cc(C2(C)CN(c3nc(-c4ccccc4)cs3)CCO2)cn1 +CC(NC(=O)c1ccco1)C(=O)OCCc1cccs1 +CCOc1ccc(-c2nc(CN(C)CCC#N)cs2)cc1 +O=c1cc(Cn2nnc(-c3ccc(F)cc3)n2)nc2sccn12 +Cc1ccccc1NC(=O)COc1ccc(N)cc1F +CCOc1ccc(CC(=O)N(CC(F)(F)F)C2CCOCC2)cc1 +CC(c1ccc(NC(=O)NC2CCC(O)CC2)cc1)N1CCOCC1 +CC(C)n1nccc1NC(=O)N(C)Cc1cnn(-c2ccccc2)c1 +Cc1nn(-c2ccccc2)cc1C1NC(=O)c2ccccc2N1C +CN(CCO)C(=O)Nc1ccccc1Cc1ccccc1 +CC(C)Oc1nnc(SCC(=O)NC2CC2)s1 +CCOC(=O)N1CCN(C(=O)CCn2c(=O)oc3ccccc32)CC1 +Cc1ccccc1OCC(C)NC(=O)N(C)CC(C)O +CCN(CC)c1ncnc(NC(C)c2ccccc2)c1N +CCOc1cccc(-c2c(N)c(C(C)=O)c(C)n2C)c1 +COc1cccc(C(=O)NCC2CCCCO2)c1O +COc1cc(NCc2cccnc2Oc2ccccc2C)ncn1 +COC(=O)c1ccc(Sc2ncc(Cl)cn2)cc1 +COc1ccc(C(=O)Nc2ccccc2N2CCCC2=O)c(OC)c1 +NC(=O)N1CCC2(CCCN(C(=O)c3cccnc3)C2)C1 +CCOC(=O)c1c[nH]c2c(OC)ccc(C)c2c1=O +N#CCOc1cccc(CC(=O)NCC2CN(C3CC3)CCO2)c1 +COc1ccc(NCc2ccc(C(F)(F)F)cc2)cn1 +Cc1ccc(NC(=O)CS(=O)(=O)c2nnc(C3CC3)n2C)cc1C +COCCCn1cnnc1C(C)NC(=O)c1cncnc1C +N#Cc1ccc(C(=O)N2CCNC(c3nc4ccccc4[nH]3)C2)cc1 +Cn1cc(CCC(=O)Nc2cc(C(C)(C)C)ccc2O)cn1 +COc1ccccc1CNC(=O)c1cc(C2CC2)nn1-c1ccccc1 +Cn1nc(CC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c2ccccc2c1=O +OCCNc1ncnc2onc(-c3ccc(F)cc3)c12 +Cc1cccc(OCC(=O)N2CCN(c3ccc(O)cc3)CC2)c1 +O=C(Cc1cc(Cl)c2c(c1)OCCO2)Nc1ccc(F)cc1 +COc1ccc(CNc2c(-c3ccccc3O)nc3cnccn23)cc1 +CCOc1ccc2oc(C(=O)OC3CCCC3=O)c(C)c2c1 +COc1ccccc1-c1noc(CCc2nc(C3CCOC3)no2)n1 +Cc1c(CC(=O)NCC(C)O)c(=O)oc2cc(O)c(Cl)cc12 +CCc1n[nH]c(NC(=O)c2cc(Br)cn2C(C)C)n1 +COC(=O)c1csc(-c2ccccc2Cl)n1 +CCN(CC)C(=O)c1cccnc1Oc1ccccc1 +COC(=O)c1cccc(CSc2n[nH]c(N)n2)c1 +O=C(NCCn1c(=O)oc2ccccc21)NC(C1CC1)C1CC1 +OCCn1ccnc1-c1cc(Cl)ccc1Cl +O=C(c1ccnc(-c2cccc(-c3cc[nH]n3)c2)c1)N1CCCCC1 +COc1ccc(NC(=O)CCC(C)C)cc1OC +CCn1cnnc1CNC(=O)c1ccc(Cl)cc1F +Cc1csc2ncn(C(C)Cc3cccnc3)c(=O)c12 +Cc1nn(C)c(C)c1C(C)C(=O)N1CCC(Nc2cccnn2)CC1 +Cc1nc2c(Cl)cc(Cl)cc2c2nc(N)nn12 +COc1ccc(C(=O)N2CCCN(S(C)(=O)=O)CC2)cn1 +O=C(Nc1cccc(CN2CCOC2=O)c1)N1CCOCC1 +N#Cc1cccnc1NCCc1ccccc1Cl +CCc1cccc(OCc2nc3cc(N)cnc3o2)c1 +O=S(=O)(NCc1cc(C2CC2)n(C2CCCC2)n1)c1ccccc1 +COc1cccc(CNc2nc3ccccc3n2C)c1 +COC(=O)CSc1nnc2c(n1)[nH]c1ccc(OC)cc12 +COc1ccccc1OCCC(=O)N1CCN(c2ncccn2)CC1 +c1ccc(-c2nccc(Sc3nc4ncccn4n3)n2)cc1 +COc1ccc(OCCNC(=O)c2ccc[nH]c2=O)cc1 +Cc1ccc(SCC(=O)NCc2ccc3c(c2)OCCO3)cc1 +COc1nn(C)c2c1CCCN(S(=O)(=O)c1cccs1)C2 +C=CCOC(=O)c1ccc(OCC2CCCO2)cc1 +CCC(=O)Nn1cnc2c(cnn2C(C)(C)C)c1=O +Cc1ccc(-c2nc(CC(=O)NCCNC(=O)C3CC3)cs2)o1 +CCc1nc(-c2ccc(C(=O)NCC(C)(C)c3ccncc3)cc2)n[nH]1 +CCOCC(=O)Nc1nnc(COc2ccc(Cl)cc2)s1 +CCCCCN(C(=O)c1cc(F)ccc1N)C(C)C +CCn1c(SCC(=O)NC2CC2)nnc1-c1ccncc1 +CCN(CC)C(=O)CCC(=O)N(C)c1ccccn1 +Nc1cc(-c2ccccc2-c2ccc(O)cc2)n[nH]1 +CN1C(=O)CCc2cc(NC(=O)c3ccnn3C)ccc21 +Cc1cccc(C(=O)Nc2ccc3oc(=O)ccc3c2)n1 +CCc1ccc(CNC(=O)c2cn3ccccc3n2)cc1 +CCN(CCC#N)S(=O)(=O)c1cccc(Cl)c1C +Cc1csc(-c2cccc(NC(=O)N(C)Cc3ccco3)c2)n1 +O=C(Cc1c(F)cccc1Cl)N1CCn2c(CO)nnc2C1 +Cn1cnnc1SCC(=O)NCC1(c2ccc(F)cc2)CCCC1 +O=C(NCC1CCCO1)c1ccc(OC(F)(F)F)cc1 +Cc1nn(Cc2ccc(F)cc2)c2sc(C(=O)NC3CC3)cc12 +CC(C)(CCC#N)CNc1cnn(-c2ncccn2)c1 +COCCNC(=O)C1c2ccccc2C(=O)N1Cc1ccc(F)cc1 +CC(NC(=O)c1cnc(Nc2ccccc2)nc1)c1cnn(C)c1 +COc1cccc(CN2CCN(c3cnn4cnnc4c3)CC2)c1 +N#Cc1ccc(NC(=O)CCc2ccc3c(c2)OCO3)cc1C#N +CCOc1ccc(-c2nc(CC(=O)N3CCNC(=O)C3)cs2)cc1 +O=C(COc1cccc(Cl)c1)N1CCC(n2cccc2)CC1 +CCCC(=O)c1ccc2c(c1)N(CC(=O)NC1CCCC1)C(=O)CO2 +Cc1ccc(CNC(=O)c2nccn2Cc2ccccc2Cl)cc1 +C=CCNS(=O)(=O)c1cnn(C(CC)CC)c1N +COc1ccc(C(=O)Nc2cc(Cl)ccc2C)c(N)c1 +CN(Cc1c(Cl)cnn1C)S(=O)(=O)c1ccc2ccccc2c1 +CC(=O)Nc1ccccc1OCc1nnc(-c2ccc(Cl)cc2)o1 +Cc1cccc(NC(=O)C2CCN(c3ccc4nncn4n3)CC2)n1 +COc1ccc(NC(=O)CN(C)C(=O)Cc2ccc(Cl)cc2)cc1 +COc1ccc(OC)c(C(C)NCc2sc(C)nc2C)c1 +COCCNC(C(N)=O)c1cccc(Br)c1 +Cc1cc(C)c(S(=O)(=O)NCC(C)(O)C2CC2)c(C)c1 +Cc1occc1C(=O)N1CCC2(CC1)Cc1ccccc1CNC2=O +COc1ccc(OCCCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1 +COC1OC2COC(C)(C)OC2C1OC(=O)c1ccccc1 +COc1ccc(OC)c(CC(=O)Nc2ccc(Cl)c(C#N)c2)c1 +NC(=O)Nc1cccc(CNC(=O)c2ccc(N3CCCC3)nn2)c1 +N#CC(C(=O)CCCOc1cccc2ccccc12)c1ccccn1 +CC(=O)Nc1ccc(C(C)=O)cc1OCC(=O)NC1CCCCC1 +CC(=O)c1ccccc1NC(=O)c1cccc(OCC2CCCO2)c1 +O=C1OC(C(=O)N2CCC(O)(C(F)(F)F)CC2)Cc2ccccc21 +Cc1noc(C)c1CNC(=O)N1CCN(Cc2cccnc2)CC1 +COc1ccc(Br)c(C(=O)NCc2ccc(C#N)cc2)c1 +CSc1ncnc(NCc2ccc(C)cc2)c1C#N +CC1CCC(CNC(=O)NCCC(=O)N2CCCC2)CC1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(Cl)cc1C +COc1cccc(OC)c1C(=O)Nc1cc(C(N)=O)ccc1Cl +O=C(OC(Cn1cncn1)c1ccc(Cl)cc1)c1ccsc1 +Cc1ccc(C)c(C(C)NS(=O)(=O)c2cnn(C)c2)c1 +Cc1noc2ncn(CC(=O)NC3CCCc4ccccc43)c(=O)c12 +CC1(NC(=O)CNC(=O)c2cc3ccccc3[nH]2)Cc2ccccc2C1 +O=C(CNC(=O)c1ccc(Br)cc1)NCc1ccccn1 +Cc1cccnc1CNC(=O)c1n[nH]c2ccccc12 +Cn1cc(C(=O)NCc2cccc(C(F)(F)F)c2)c2cccnc21 +Cc1ccsc1CNC(=O)c1c(O)cc(F)cc1F +NC(=O)c1ccc(NC(=O)Cc2cccc(F)c2F)cn1 +Cn1ccnc1C(=O)NC1CN(Cc2nccs2)C2CCCOC12 +COCCC(=O)Nc1ccc2c(c1)CCC(=O)N2C +CC(C)(C)CC(NC(=O)Nc1cccnn1)C(F)(F)F +CN(Cc1ccccc1N1CCOCC1)C(=O)CCC(C)(C)C +Cc1cccc(N2Cc3nc(N4CCOCC4)ncc3C2=O)c1 +Cc1nn(C)c(C)c1CCC(=O)N1CCC1c1ccc(F)cc1 +O=C(Nc1ccon1)c1cc2cccnc2n(Cc2ccccc2)c1=O +Cc1ccc2c(c1Cl)CCNC2c1cnccn1 +O=C(CCn1ccnn1)NCc1ccc(Oc2ccccc2)cc1 +CC(=O)N1CCC(C(=O)N(C)CCOc2ccccc2C)CC1 +CCN(Cc1noc(C)n1)C(=O)CCC(=O)Nc1cc(C)ccc1F +C=CCN(Cc1ccc(OC)cc1)C(=O)Nc1nc(C2CC2)cs1 +COC(=O)c1cnn(-c2cccc(Cl)c2)c1N +CC(O)c1cccc(-c2ccnc3c2ccn3C)n1 +Cc1cc(N2CCCC(c3nc(C)no3)C2)nc(N)n1 +CCOC(=O)CN(CC)C(=O)c1cc(Cl)c[nH]1 +Fc1ccc2c(c1)CCNC2COc1ccccc1 +CC1CN(C(=O)NCc2ccn(C)c2)CCN1CC(F)(F)F +COC1CCN(C(=O)c2cc(C)ccn2)CC1Cc1ccccc1 +COc1ccc(CN(C)S(=O)(=O)N2CCCCCC2)cc1OC +Cc1nc2ccccc2c(=O)n1CC(O)COc1ccc(C#N)cc1 +NC(=O)c1cnc(NCCSc2ccccc2)c(Cl)c1 +CCN(C(=O)c1csc(C2CC2)n1)c1nc2ccccc2s1 +CCNC(=O)C1(NC(=O)c2cnn[nH]2)CCCCC1 +C#Cc1cccc(NCC(=O)Nc2ccc(C(C)=O)cc2)c1 +Cc1cnn(C(C)C2CC2)c1NC(=O)c1ccc(C#CC(C)(C)O)o1 +CN(C(=O)c1ccc(CCNS(C)(=O)=O)s1)c1ccccc1 +Cc1csc(C(C)(C)NCCS(=O)(=O)c2ccc(C#N)cc2)n1 +O=C(Nc1cccnc1)c1cccc(S(=O)(=O)NC2CC2)c1 +CCCOc1ccc2c(c1)C(c1ccncc1C)NCC2 +CC(C)c1nnc(-c2coc(S(=O)(=O)N3CCCCC3C)c2)o1 +Cc1ccc(F)cc1NCCOc1ccc(S(N)(=O)=O)cc1 +CCOc1cccc(C(=O)Nc2ccc(O)cc2)c1 +CCN(CCO)C(=O)c1nn(-c2ccccc2F)c2c1CCC2 +CCC(=O)Nc1ccc(NC(=O)C2CCCCC2)nc1 +Cc1ccc(C)c(S(=O)(=O)CC(=O)Nc2ccccc2Cl)c1 +O=C(CCc1ccco1)Nc1n[nH]c(N2CCCCC2)n1 +CCc1ccsc1C(=O)Nc1cccc(-n2cnnn2)c1 +COc1cc(OC)cc(C(=O)n2c(C)nc3ccccc32)c1 +O=C(NCCCOCc1ccccc1)c1cnc2ccccn2c1=O +CCCC(NC(=O)c1cccc(-n2cnnn2)c1)c1ccccc1 +CC1CCCN(S(=O)(=O)N2CCOCC2C2CC2)C1 +CC(C)OCCCNS(=O)(=O)c1ccc(Cl)cc1 +CCCc1nc(C)c(C(=O)NCCN2CC(C)OC(C)C2)s1 +Cc1ccc2ncc(C(=O)NC3CCN(c4cccs4)CC3)n2c1 +Cc1ccc(C(C)NC(=O)COc2cccc3c2OC(C)(C)C3)o1 +COC(=O)C(C)CN(C)S(=O)(=O)c1ccccc1OC +COc1cc(C(=O)NCCCc2cccs2)on1 +Cc1noc(CCNS(=O)(=O)c2cc(C(F)(F)F)ccc2C)n1 +CN1c2ccccc2C(=O)NC12CCN(CC(F)(F)F)C2 +Fc1ccc(-n2nnnc2CSc2ccccn2)cc1 +CSc1ccc(C2CC(O)=Nc3n[nH]cc32)cc1 +CN(CC(=O)Nc1ccccc1Oc1ccccc1)S(C)(=O)=O +CCOc1ccccc1N(C)C(=O)c1ccc(Br)cn1 +Cc1ccc(F)c(NC(=O)c2ccc(N3CCOC3=O)cc2)c1 +CC(C)Cn1c(-c2ccccn2)nc2c1c(=O)[nH]c(=O)n2CC(C)C +CC(c1ccccc1)N(C)C(=O)Nc1ccccc1CC(N)=O +Cc1ccc(-c2ncco2)cc1NC(=O)C(C)Cc1c(C)n[nH]c1C +CC1(C)CN(Cc2cccc(-c3ccccn3)c2)CCO1 +CC(=O)N1CCN(C(=O)c2coc(NC(=O)c3ccccc3)n2)CC1 +Cc1ccc(C(C)C)c(OCC(=O)N2CCc3nnc(N)cc3C2)c1 +COc1cc(-c2ccno2)ccc1S(=O)(=O)NCc1ccccc1 +CC1(C)CCC(CNC(=O)c2cc(C(N)=O)c[nH]2)CC1 +CN(C)C(=O)c1cncc(C(C)(C)C)c1OC1CC1 +CN(Cc1nc2ccccc2n1C)C(=O)C1Cc2cc(F)ccc2O1 +CCC1CCCN(C(=O)NCc2cccc(S(N)(=O)=O)c2)C1 +Cc1occc1-c1nnc(SCC=Cc2ccccc2)n1N +Cc1nn(CCO)c(C)c1CNc1ccc2oc(C3CC3)nc2c1 +COc1ccc(C(=O)NCC(O)c2ccc(C)o2)cc1OC +CC(C)CN(CC(C)C)C(=O)C1CC(=O)N(c2ccc(F)cc2)C1 +CC1CCCC(NC(=O)NC2CCN(S(C)(=O)=O)CC2)C1C +Cc1cccc(C(=O)Nc2cnc3ccccc3c2)c1 +CCc1nn2c(CNC(=O)c3ccsc3)c(C)nc2s1 +Cn1[nH]c(=O)c2c(C(=O)Nc3ccncc3)cc(C3CC3)nc21 +Cc1ccc(N(C)C(=O)CN(C)S(C)(=O)=O)c(C)c1 +Cc1cnc(NC(=O)C2CCCN2c2ncnc3sccc23)s1 +CCNS(=O)(=O)c1cccc(C(=O)NCc2cccs2)c1 +Clc1ccc(-c2noc3ncnc(N4CCOCC4)c23)cc1 +Cc1ccc(C(=O)NC(C)c2ccccc2F)cc1S(N)(=O)=O +O=C(C1CCOCC1)N(C1CC1)C1CCCc2ccccc21 +COc1ccc(C(O)CCNc2ccc(C#N)cc2)cc1N +CCCCn1nc(C(=O)Nc2cc(C#N)cn2C(C)(C)C)ccc1=O +Cc1ccccc1OCC(=O)N1CCNC(=O)CC1 +CCc1onc(C)c1NC(=O)NCCc1cc(C)ccc1OC +Cc1cc(C(O)CCNc2c(C)cccc2C)ccc1F +CCS(=O)(=O)Nc1ccc(NC(C)c2ccccc2)cc1 +CCCc1nonc1NC(=O)c1ccc(F)c(F)c1F +Cc1cccc(CNC(=O)c2cccc(N)c2)c1F +Cc1ccc(CC(C)NC(=O)c2ccc3ccccc3n2)s1 +Cc1cc(=O)[nH]c(NCc2ccc(F)cc2F)n1 +Cc1ccc(-c2n[nH]c(C)c2NC(=O)c2ccccc2Cl)o1 +COc1ccc(C(C)NCCc2sc(C)nc2C)cc1NC(C)=O +COc1ccc(NC(=O)CCn2ccc3ccccc32)c(OC)c1 +Clc1ccc2[nH]c(SCc3ccccn3)nc2c1 +O=C(Nc1ccccn1)c1ccc(Cn2cncn2)cc1 +CCc1ncc(C(=O)N(C)Cc2ccc(-c3ccccc3)cc2)cn1 +O=C(c1cccc(S(=O)(=O)N2CCOCC2)c1)c1cnccn1 +CC(OC(=O)CCNC(=O)c1ccco1)c1cccc(F)c1 +Cc1nc(-c2ncccn2)sc1C(=O)N(C)Cc1ccncc1 +Cc1occc1-c1nnc(CCC(=O)NCC(=O)NC(C)C)o1 +CCN(CC(C)C#N)C(=O)Cc1ccc2c(c1)CCC2 +Cc1ccc(C(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)cn1 +Cc1nn(C)cc1C(=O)N1CCCCC1CCc1ccccc1 +CN(C)C(=O)c1cccc(OC(=O)CCc2ccccc2Cl)c1 +CC(C)N(C(=O)Cn1cc(Cl)cn1)C1CCCC1 +COc1ccc(OC)c(NC(=O)c2nc(SC)ncc2Cl)c1 +Cc1cc(NC(=O)N2CCN(CC(=O)NCC(C)C)CC2)no1 +CC1CCN(C(=O)COC(=O)c2ccccc2NCCO)CC1 +CCC(C)C(NC(=O)Cc1cn(C)c2ccccc12)C(N)=O +Cc1cc(CNC(=O)C2(C)Cc3ccccc3C(=O)O2)ccc1F +Cc1cccc(C(=O)Nc2nnc(Cc3ccccc3)o2)c1 +CC(Cc1cnccn1)NC(=O)CCc1c[nH]c2ccccc12 +CN(CC(=O)NC(C)(C)C)C(=O)CN1CCc2cc(F)ccc2C1 +CCOC(=O)CN(C)C(=O)c1cc(Cl)cn1C(C)C +O=C(CO)c1ccc(S(=O)(=O)C2CCCC2)cc1 +COc1ccc(NC(=O)NCC(C(C)C)N2CCOCC2)cn1 +Cn1ncnc1CNC(=O)NC1CCN(c2cccc(Cl)c2)C1 +O=C(Nc1ccc(-c2nnc3n2CCCCC3)cc1)C1CCCO1 +CC(C)NC(=O)NCC(C1CCOC1)N1CCOCC1 +COc1ccccc1C(=O)C1CCCN1C(=O)CC(C)C +CCOC(=O)CSc1nnc2c3c(C)c(C)sc3ncn12 +O=c1oc2cc3c(cc2c2ccccc12)OC=CO3 +CC(CCc1ccccc1)NC(=O)Nc1ccn(CC(N)=O)n1 +COC(=O)C1CCCc2nc(-c3ccc(OC)cc3)nn21 +CCCN(CC(=O)OC)C(=O)c1ccc(OC)cc1 +CN(C)S(=O)(=O)N1CCCC(C(=O)NCCN2CCOCC2)C1 +CNC(=O)C(NC(=O)COc1ccc(C)cc1OC)c1ccccc1 +NC(=O)Cn1cc(Nc2ccc3nnc(C(F)(F)F)n3n2)cn1 +CCNC(=O)CNc1ccc(S(=O)(=O)C(F)F)cc1 +COc1ccc(CCCN(C)Cc2n[nH]c(=O)[nH]2)cc1 +CCn1c(SCC(=O)Nc2nc(C)cs2)nc2ccccc21 +O=C(CCC(=O)c1ccc2c(c1)OCCO2)OCc1ccccc1 +CCOC(=O)CCNC(=O)c1ccccc1Cl +N#Cc1c(-c2ccco2)nc2sc(-c3ccncc3)nn12 +CNC(=O)c1ccc(CSc2ccccc2O)cc1 +CCCSc1cc(OC)cc2c1S(=O)(=O)NC2 +COc1cc(C)c(C(=O)NCCc2cc(F)ccc2F)cc1OC +COc1cc(C#N)ccc1OC(=O)c1cn(C)nc1-c1cccs1 +O=C(Nc1nc2ccccc2[nH]1)c1ccc2c(c1)OCCO2 +CC(CN1CCOCC1)NC(=O)C(C)n1cccn1 +COC(=O)c1ccc(Cl)cc1S(=O)(=O)N1CCCCC1 +CN(C)C(=O)CN(C)C(=O)c1ccc2c(c1)C(=O)c1ccccc1-2 +COc1cc(C2CC(O)=Nc3c2cnn3C(C)C)ccc1O +COC(=O)C1CCCCCC1NC(=O)CCn1cc(C)cn1 +CCOc1c(Br)cc(CNn2nnnc2N)cc1OC +COC1CCCN(Cc2cnc3c(C)cccn23)C1 +Cc1nc(-n2[nH]c(C)c(CC(=O)N3CCOCC3)c2=O)sc1C +O=C(CNc1cc(F)ccc1F)Nc1ccnn1C1CCCC1 +CCCC(C)N1CC(C(=O)Nc2ccc(-n3ccnc3)cc2)CC1=O +CC(C)S(=O)(=O)c1ccc(COC(=O)CN)cc1 +CCn1nc(C)c2c(C(=O)Nc3ccc(OC)cc3C)cc(C)nc21 +CC(NS(=O)(=O)c1cn[nH]c1)c1cccc(F)c1 +COc1ccc(S(N)(=O)=O)cc1NC(=O)C(C)C +Cn1c(SCC(=O)OCc2ccccc2)nc2ccccc2c1=O +CCC(C)C(=O)NCc1ccc(-n2cnc3ccccc32)nc1 +O=C(OCCn1cccn1)C1(c2ccc(F)cc2)CC1 +CC(C)NC(=O)Cn1nc2c3ccccc3nc(C(C)C)n2c1=O +Cc1csc(=O)n1CC(=O)NC(C)C(=O)N1CCCC1 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1cccs1 +COc1ccc(OC)c(C(=O)CN2CC(C)OC(C)C2)c1 +CC(=O)Nc1ccc(-c2cn(CCC#N)cn2)cc1 +Cc1noc(C(C)N2CCN(CC(O)c3ccco3)CC2)n1 +COc1ccc(F)cc1NC(=O)c1cccc(-n2cccc2)c1 +CN(CC(=O)N1CCOCC1)C(=O)c1c[nH]nc1-c1ccc(F)cc1 +Cc1ccc(F)c(NC(=O)NCc2ccccc2-n2ccnc2C)c1 +CCC(=O)c1cc(C)ccc1OCC(=O)NCc1ccc(F)cc1 +Cc1ccc(-c2csc3ncn(CC4CCCO4)c(=O)c23)cc1 +CS(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1C#N +Cc1cc(C)n(-c2ccc(C(=O)NCC(O)c3ccncc3)cc2)n1 +COC(=O)N(C)c1ccc(NC(C)C(=O)NC(C)(C)C)cc1 +O=C(c1ccc[nH]1)N1CCC2OCCN(Cc3ccncc3)C2CC1 +O=C(NCCCCN1CCOCC1)c1ccc2[nH]cnc2c1 +Cc1cc(C)cc(NC(=O)c2nn(C)c(C)c2Br)c1 +Cc1occc1CN(C)C(=O)c1cc(C(C)C)[nH]n1 +COC(=O)C(C)NC(=O)CCc1ccc(C(C)C)cc1 +Nc1c(NCc2ccc(F)cc2)ccc2scnc12 +COc1cnc(C(=O)Nc2ccc(F)c(Cl)c2)cc1O +O=C(NC1CCCC1)C1CCCN(c2nnc(-n3cccc3)s2)C1 +CC(=O)Nc1ccc(S(=O)(=O)C(C)C)cc1N +Cc1c(CO)cnn1-c1cccc(C(F)(F)F)c1 +CNS(=O)(=O)c1cccc(CNC(=O)N2CCCC2)c1 +CCNC(=O)c1ccc(NC(=O)NC2(c3ccccc3F)CC2)cc1 +Cc1cc(C)n2nc(CC(=O)N(C)Cc3cc(C)on3)nc2n1 +COc1ccc(CCNC(=O)c2cc(F)ccc2C)c(OC)c1OC +COc1ccccc1CNC(=O)c1cc(F)ccc1-n1cnnn1 +N#Cc1ccccc1OCC(=O)N(CCO)C1CC1 +Cc1nc(NC(=O)c2ccc(Br)cc2)sc1C +O=C(OCCOc1ccccc1F)C1CCN(c2ncccn2)CC1 +CCN(CC)C(=O)CCC(=O)N1CCc2ccccc21 +COC(=O)C(C)CSc1ncnc2c(C)cccc12 +CC(C)CNC(=O)C1(NCc2cccc(C(=O)N(C)C)c2)CCCC1 +CCCC(=O)Nc1nnc(CSc2ccccc2)s1 +COc1ccc(C(=O)N2CCN(C(=O)C3CC=CCC3)CC2)cc1 +CC(c1ccc(F)cc1)n1c(=O)[nH]c2ccsc2c1=O +O=C(c1ccc(-c2ccc(F)cc2)o1)N(Cc1ccccn1)C1CC1 +Cc1cc2[nH]c(C)c(Cc3ccccc3Cl)c(=O)n2n1 +COCCCNc1ncnc(Nc2cccc(Cl)c2Cl)c1N +CCOC(=O)C(CC)C(O)c1ccc(F)c(C)c1 +Cc1cc(NC(=O)CN2CCOC(C)(C)C2)n(-c2ccccc2)n1 +COC(=O)C(C)S(=O)(=O)Nc1c(C)cccc1O +Cc1c(-c2ccccc2)nc2sc(C3CCCO3)nn12 +COc1ccccc1OC(=O)c1[nH]c(C)c(C(=O)OC(C)C)c1C +CC(C)(C)c1nnc(SCc2ccccc2F)n1N +CCCCn1nc(C(N)c2cccs2)ccc1=O +Cc1cc(=O)oc2cc(NC(=O)COc3ccccc3)ccc12 +Cc1cnc(C(C)CNC(=O)Nc2ccc(-n3ccnn3)cc2)s1 +CCOc1cccc(C(O)CCN2CCOCC2)c1 +COc1nc(N2CC(C)C(O)(C3CC3)C2)ncc1F +CCCc1ccc(C(=O)NC(C)c2ccncc2)cc1 +CCc1noc(C)c1C(=O)N1CC(c2ccccc2)OCC1(C)C +COc1ccc(-c2nc3scc(N)n3n2)cc1Cl +O=C(NCCCn1cncn1)c1cc2c(s1)CCC2 +Cc1cc(=O)oc2cc(OCCSc3nnnn3C(C)C)ccc12 +N#Cc1ccc(-c2noc(Cn3nnc4ccccc4c3=O)n2)nc1 +c1cnn(CCCOC2CCC3C2OCCN3C2CCCCC2)c1 +Cc1[nH]c2ccccc2c1C(=O)Nc1ccc(C(N)=O)cc1 +Cc1nn(C)cc1S(=O)(=O)N1CCN(c2ccccn2)CC1 +Cn1c(=O)n(CC(=O)Oc2ccccc2F)c2ccccc21 +CCn1cc(NC(=O)c2cccc(C)c2)c(C(=O)Nc2ccccc2)n1 +CS(=O)(=O)c1ccc(Oc2nccnc2C#N)cc1 +CCCc1noc(COc2ccc(C#N)c(F)c2)n1 +Cc1nc(C2CCCN(C(=O)c3ccccc3OC3CCC3)C2)no1 +Cn1cc(C(=O)Nc2cc(N)ccc2Cl)cn1 +COc1c(Cl)c2c(c(OC)c1OC)C(C)(C)CNC2 +COCC(=O)NC(C)c1nc2ccccc2n1CC(=O)NC(C)C +Cc1cccc(NCc2nnc(-c3ccc(F)cc3)o2)c1 +COc1ccc2cc(C(=O)N3CCn4c(nnc4C4CC4)C3)[nH]c2c1 +CNC(CCC(=O)OC)C(=O)c1cc(Cl)ccc1C +CN(CC(=O)c1ccc(O)cc1)C(=O)c1cc2ccccc2n1C +C=CCOc1cccc(NC(=O)c2n[nH]c3c2CCC3)c1 +CC(C)C(=O)Nc1ccc(Nc2cc(-n3ccnc3)ncn2)cc1 +O=C(Nc1ccc(Cl)cn1)C1CCCN(C(=O)C2CCCCC2)C1 +CCOc1cc(C(=O)N(C)C)ccc1NCc1cc(F)cc(F)c1 +CCOC(=O)c1cc2c(=O)[nH]c(N3CCOCC3)nc2nc1N +Cc1nc2c(Nc3cccc(C(N)=O)c3)ncnc2[nH]1 +Cc1cc(Cl)ccc1OC(C)c1n[nH]c(-c2ccncc2)n1 +COc1ccc(CCNC(=O)c2c(C)oc3nc[nH]c(=O)c23)cc1 +N#CC(CCC(=O)Nc1ccccc1)c1ccncc1 +COC(=O)c1cn(-c2cccc(C(F)(F)F)c2)c(C)c1C(=O)OC +CC(C)(C)C1CC(C(C)(C)C)C(C(=O)N2CCOCC2)C1=O +COc1ccc(S(=O)(=O)C2CCN(C(=O)C3CC3)CC2)cc1 +CC(C)N(C(=O)CSc1ccc(F)c(F)c1)C(C)C +Cn1ccnc(NC(=O)c2ccc(OCC3CC3)nc2)c1=O +CNC(=O)c1cc(OC)ccc1NC(=O)Cc1c(F)cccc1F +O=C(Cn1cccnc1=O)NCc1ccc2c(c1)OCO2 +COC(=O)Nc1ccc(CNc2ncnc3[nH]cnc23)cc1 +Cn1cc(CNS(=O)(=O)c2cc(C(N)=O)n(C)c2)cn1 +CCOCC1CCCN(C(=O)c2ccc(OC(F)F)cc2)C1 +CCCCc1ccc(NC(=O)Cc2c(C)nc(C)[nH]c2=O)cc1 +CC(C)(C)NC(=O)Cc1n[nH]c(-c2cccnc2)n1 +CCC(C)c1ccc(NC(=O)c2ccc(=O)[nH]c2)cc1 +N#Cc1cc2c(nc1SCC(=O)Nc1ccncc1)CCCC2 +N#Cc1ccc(C(=O)CSc2n[nH]c(=O)n2C2CC2)cc1 +COC(=O)c1ccc(CSc2nc3ccncc3[nH]2)cc1 +N#Cc1cccc(Oc2ccc(NC(=O)c3ccoc3)cc2)c1 +CCc1noc(C)c1C(=O)OCC(=O)Nc1cc(C)on1 +N#Cc1ccc(OCCOC(=O)c2cc3ccccc3c(=O)[nH]2)cc1 +CNC(=O)c1cccc(OCc2nnc(-c3ccc(C)cc3)o2)c1 +CCn1c(-c2ccc(OC)cc2)ccc(CC#N)c1=O +Cc1csc(CCC(=O)c2ccc(F)c(C)c2)n1 +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1cc(Cl)c[nH]1 +COc1cccc(C2NCCc3cccc(OC)c32)c1 +COC(=O)CNC(=O)CCN1Cc2ccccc2-c2ccccc2C1 +CNC(=O)C1CN(C(=O)c2ccc(Cl)cc2)c2ccccc2O1 +Cc1ccc2[nH]cc(S(=O)(=O)c3ccc(C#N)c(F)c3)c(=O)c2c1 +O=C(NC1CC1)C1CCCN(c2nnc(-n3cccc3)s2)C1 +Cc1noc(CNc2cc(Cl)ccc2C(=O)N(C)C)n1 +Nc1nc2ccc(F)c(F)c2n1CC1COCCO1 +Cc1cc(-c2cncnc2-c2ccc(N3CCOCC3)nc2)on1 +C=CCSc1nnc(-c2ccc(OC)c(OC)c2)o1 +COc1cc(OC)c(NC(=O)c2ccc(N(C)C)cc2)cc1F +Cc1cccnc1NC(=O)Cc1c(C)nn(C)c1C +COc1cc(OC)c(NC(=O)c2cccs2)cc1NC(C)=O +Cc1noc(C2CCN(C(=O)c3ccccc3)CC2)n1 +Cc1cccc(NC(=O)Nc2nnc(Cc3ccc(F)cc3)o2)c1 +COc1ccc(Nc2ncccc2NC(=O)c2ccoc2)cc1 +Cc1ccc(-c2cc(C(=O)NC(C)C(C)C)on2)cc1 +Cc1cc(NC(=O)c2cnc3ccccn3c2=O)c2ncccc2c1 +COCC(=O)N1CCC(C(=O)NCCc2ccc(C)o2)CC1 +CCCOC(=O)CSc1nnc(C(C)(C)C)c(=O)n1N +CCN(CC)C(=O)c1cccc(NC(=O)c2ccccc2OC)c1 +CCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CCOC +Cc1cccc(Nc2ncnc(N3CCCC3)c2N)c1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)C1CCCCC1 +CC1COC2(CCN(C(=O)c3cccn3C)CC2)C1 +Cc1cccn2c(=O)c3cc(C#N)c(=O)n(-c4nccs4)c3nc12 +CCn1c(SCCCO)nc2sc(C)c(C)c2c1=O +CC(=O)c1ccccc1NC(=O)COCCc1ccccc1 +Cc1cc(C)cc(OCCNC(=O)C2CCCO2)c1 +CCOc1ccc(Cl)c(C(=O)Nc2nc(C)cs2)n1 +CCn1nc(-c2ccc(C)cc2C)cc(CO)c1=O +C#CCn1c(=NC(=O)c2ccn(C)n2)sc2cccc(F)c21 +Cc1ccc(C(=O)Nc2ccc(-c3nncn3C)cn2)c(C)c1 +CCN(C(=O)Cn1cnnn1)C1CCN(c2ccccc2)C1=O +CCNC(=O)CNC(=O)Nc1ccc(C(=O)NCC)cc1C +O=C(c1ccsc1)N1CC2CN(c3ncccn3)CC2C1 +CN(C)c1ccc(NC(=O)COc2ccc(F)c(Cl)c2)cn1 +CC(c1ccc(C(F)(F)F)cc1)N1CCNC(=O)C1 +CCn1cc(NC(=O)c2cc(Br)cn2C(C)C)cn1 +CC(=O)Nc1ccccc1OCc1cc(C#N)ccc1F +O=C(NCc1ccc2ccccc2c1)NCC1CCOC1 +CC(=O)Nc1nnc(SCc2ccc(C)cc2)s1 +CC(=O)c1ccc(NCCOc2cccc(N)c2)cc1 +COC(=O)C(Cc1cc(OC)ccc1OC)NC(C)=O +Cc1ccc(Cn2cc(NC(=O)c3csnc3C)cn2)cc1 +O=C(NCCOc1cccc(F)c1)c1ccncc1F +COCCNC(=O)c1cc(-c2ccc(Cl)cc2)cs1 +COC(=O)c1cc(N2CC(NS(C)(=O)=O)C(C(C)C)C2)ncn1 +CCn1c(=O)c2c(nc3n(CC)c(C)cn23)n(C)c1=O +Cc1cc(=O)[nH]c(SC(C)C(=O)Nc2cccc(Cl)c2)n1 +CCSc1cccc(C(=O)Nc2nnc(C3CCCO3)o2)c1 +Cc1n[nH]c(-c2ccc(NC(=O)CCNC(=O)c3ccccc3)cc2)n1 +Cc1c(Cl)cccc1-c1ccc2nc(N)nn2c1 +CS(=O)(=O)Nc1ccc(C(=O)NCCN2CCOCC2)cc1 +O=C(Nc1cccc(C(=O)c2ccccc2)c1)NC1CC2CCC1O2 +COc1ccc(C)cc1-n1ccnc1SCCC#N +CCOC(=O)C1=C(CC)NC(=O)NC1c1ccccc1C +CC(C)CC(CO)NC(=O)Nc1ccnc(C(=O)N(C)C)c1 +O=C(OCC1CCCO1)c1ccc(-n2cncn2)cc1 +COC=C(C(O)c1ccc(C)cc1)n1nnc2ccccc21 +Nc1c(NCC(=O)NC2CC2)ccc2scnc12 +O=C(NC(c1nccs1)C1CC1)N1CCCC1CO +Cc1ccc(C(=O)Nc2cnn(CCc3ccccc3)c2)cc1 +O=S(=O)(NCCc1ccc(Cl)cc1)c1cccc(O)c1 +COc1ccc(Cl)cc1CN(C)S(=O)(=O)CCCO +Cc1cnn(CC2CN(C(C(N)=O)c3ccccc3)CCO2)c1 +Nc1cc(NC(=O)CSc2ccccc2)ccc1Cl +Cc1cccc(NC(=O)CCNC(=O)Nc2ccccc2)c1 +CC(NC(=O)N1CCCN(c2ncccc2C#N)CC1)C1CCCO1 +O=C(CCC(=O)NCc1ccco1)NCc1ccccc1 +CC(=O)Oc1ccc2oc(=O)c3c(c2c1)CCCN3 +CCNC(=O)c1nc(C(=O)NCc2ccccc2)cs1 +Cc1n[nH]c(C)c1CC(=O)N1CCC(c2cc3ncccc3cn2)CC1 +O=C(c1cn2ccsc2n1)N1CCN(CCOCCO)CC1 +COc1ccc(C(=O)NC(C)c2ccc(O)cc2)cc1 +O=C(Cc1ccc[nH]1)Nc1ccnc(Sc2ccccn2)c1 +Cc1oc(-c2cccs2)nc1Cn1c(-c2ccccn2)noc1=O +CC(c1cccc(Cl)c1)N(C)C(=O)NCC(=O)N1CCCC1 +CCN(C(C)=O)C1CCN(c2nc(C)nc3c2cnn3C)C1 +O=C(NCCNC(=O)C1CCCCC1)c1ncoc1-c1ccccc1 +Cc1cc(C(=O)OCc2cc(C)on2)c2ccccc2n1 +CCCNC(=O)NCCS(=O)(=O)N1CC(C)OC(C)C1 +COC(=O)CNc1cc(C)nc2nc(-c3ccccc3C)nn12 +COC(=O)c1ccc(-c2nc(C3C=CC=NC3=O)no2)cc1 +CC(C)S(=O)(=O)NCCCn1nc2n(c1=O)CCCC2 +COCCn1ccc2c(C(=O)Nc3n[nH]c(C(C)C)n3)cccc21 +Nc1ccc2nc(SCC(=O)NCc3ccc(F)cc3)sc2c1 +N#Cc1ccc(OC(=O)Cn2nnc3ccccc3c2=O)c(Cl)c1 +COC1CCCC1OC(=O)Cn1ncc(=O)c2ccccc21 +CC(CCc1ccccc1)CC(=O)NCc1cscn1 +COc1cc(N2CCC3(CC(=O)N(c4ccc(C#N)cc4)C3)C2)ncn1 +O=C(NC=Cn1cnc2cc(C(F)(F)F)ccc21)c1ccc(F)cc1 +Cc1nc(NC(=O)c2cc(N)ccn2)sc1C(=O)N(C)C +Cc1ccc2oc(C(=O)N(C)c3ccc(Br)cn3)cc2n1 +CCCOC1CCCN(C(=O)c2ccc(C)cc2C)C1 +O=C(CSc1ccc(C(F)(F)F)cn1)NCc1ccco1 +N#Cc1ccc(NC(=O)CCc2ccc3c(c2)OCO3)cc1 +CC(C)(C)C(=O)NCc1cc(-c2ccccc2)no1 +COCc1cc(C)nc(N2CCc3ccccc32)c1C#N +O=C(Nc1cnc2ccccc2n1)c1ccncc1 +COCCOCC1CCN(C(=O)c2ccc3cc[nH]c3c2)C1 +COc1cc(C)c(Cl)cc1S(=O)(=O)NCC(C)C +COC(=O)c1c(C2CC2)csc1NC(=O)c1ncoc1C(C)C +CCc1nc(C)c(C(=O)NCCNC(=O)c2ccccc2)s1 +COc1cn(-c2cccc(C(F)(F)F)c2)nc1C(=O)NC1CC1 +Cc1noc(-c2ccc(F)c(Br)c2)n1 +C#CCC(OC(=O)c1ncn(-c2ccccc2)n1)C1CC1 +N#CC1CCCN(S(=O)(=O)c2ccc(Cl)cc2)C1 +Cc1ccc2cccc(Nc3ncnc(Nc4nccs4)c3N)c2n1 +Cc1ccc(N)c(C)c1NS(=O)(=O)c1cn[nH]c1 +Cc1nn(-c2ccccc2)cc1CN(CCC#N)CC1CC1 +CC1Cc2cc(S(N)(=O)=O)ccc2N1Cc1ccccc1C#N +CCC(C)(C)NS(=O)(=O)c1cc(C)cc(S(C)(=O)=O)c1C +Cc1nn(-c2ccc(-c3ccc(F)cc3)nn2)c(C)c1O +CC(=O)NC(C(=O)Nc1cc2c(cc1Cl)OCCO2)C(C)C +COc1ccc(NC(=O)c2ccc(F)nc2)cc1NC(C)=O +CC(OC(=O)c1ccc(C(=O)N(C)C)cc1)c1cccc(F)c1 +O=S(=O)(NCc1cnn2ccccc12)c1ccccc1F +Cc1ccc(C(=O)OCC(=O)NC(C)c2ccc(F)cc2)s1 +COC(=O)c1ccccc1Nc1nc(C(C)=O)cs1 +Cc1cccc(N(C)CC(O)Cn2cccn2)c1C +CCC(COC)NC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +COC(=O)c1ccsc1N(C(C)=O)c1ccccc1 +CCNC(=O)CCCC(=O)NCc1sccc1Br +Cc1scc(C(=O)Nc2nnc(C3CC3)s2)c1-c1ccccc1 +CCn1c(C(=O)N(C)CC(N)=O)cc2ccccc21 +CC(C#N)Cn1cccc(OCCc2ccccc2)c1=O +Cc1ccnc(NC(=O)Cc2csc(NC(=O)C3CC3)n2)c1 +O=c1ccc2ccc(OCc3nc(-c4ccncc4)no3)cc2o1 +CNC(=O)c1ccccc1SCc1ccccc1 +Cc1nn(C)c(C)c1CC(=O)N1CCN(c2nccs2)CC1 +CC(=O)c1cc2c(cc1NC(=O)Nc1cccc(Cl)c1)OCCO2 +CCOC(C(=O)NCc1c(C)cc(C)[nH]c1=O)c1ccccc1 +O=C(c1cnsc1)N1CCC(c2[nH]ncc2-c2ccncc2)CC1 +Cc1nc(C(C)C)sc1C(=O)N(C)Cc1cnn(C)c1 +CC(C)c1nc(C2CCCCCN2C(=O)CCc2cccnc2)no1 +COc1cc(NCc2ccncc2)nc(C2CCCO2)n1 +O=C(Nc1ccc2c3c(cccc13)CC2)c1ccc(-n2ccnc2)nn1 +Cn1cc(NC(=O)c2ccon2)cc(Br)c1=O +Cc1cc(Br)ccc1NC(=O)c1cccc(NC(N)=O)c1 +CC1CN(S(=O)(=O)Nc2cccn(C)c2=O)CC(C)O1 +COc1cccc(C2NCCc3ccc(NC(C)=O)cc32)n1 +CC(=O)Nc1ccc(CC(=O)C(C#N)c2nc(C)cs2)cc1 +Cc1ccc(NC(=O)C23CCC(CC2=O)C3(C)C)c(C)c1 +O=C(NC1(c2ccc(F)cc2F)CCOCC1)c1cscn1 +O=C(c1ccccc1Cn1cncn1)N1CCc2cc(F)ccc2C1 +CN(CC(=O)Nc1nncs1)c1cccc2ccccc12 +O=c1[nH]nc(SC2CCCCC2)n1CC1CCCO1 +Cc1cccc(OCC(=O)N(Cc2ccco2)Cc2ccco2)c1C +CSc1nnc(NC(=O)CSc2nc(C)n[nH]2)s1 +COc1cccc(-n2ccnc2SCc2n[nH]c(=O)[nH]2)c1 +COc1cc(S(N)(=O)=O)c(OC)c(S(N)(=O)=O)c1 +O=C(CNC(=O)c1cccc(Cl)c1)NC1CCc2c(O)cccc21 +O=C(CS(=O)(=O)c1ccccc1)Nc1ccc2ccccc2c1 +Cc1nn(Cc2cc(Cl)c3c(c2)OCO3)c(=O)c(C#N)c1C +Cc1c(Cl)cccc1NC(=O)NCc1ncn(C)n1 +CCOC(=O)c1cnn(-c2nc(C)cc(C)n2)c1NC(=O)C1CC1 +CC(C)(C)n1nc(C(=O)NC2CCCCNC2=O)cc1C1CC1 +COc1ccc(C)cc1C(=O)CCCC(=O)N1CCCCC1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(NC(C)=O)cc1 +CCC1CCc2nc(NC(=O)c3ccoc3)sc2C1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)OC1CCCCC1=O +Cc1c(C(=O)OCCNC(=O)c2ccncc2)sc2nccn12 +COCc1c(C(=O)Nc2ccccc2C)nnn1-c1ccccc1 +Cc1cc(=O)c(O)c(CN(C)C)n1C1CCCCC1 +CCn1nc(C)c(NC(=O)Nc2cnn(-c3ccccc3F)c2)c1C +CC(C)n1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)n1 +Cc1cnc(NC(=O)c2occc2COc2cccc(C#N)c2)s1 +Cn1cc(C(=O)Nc2ccc(C(=O)NC3CC3)cc2)c(C(C)(C)C)n1 +Cc1ccc(-c2nc3c(N)cccn3c2C)c(C)c1 +CC(NC(=O)N1CCN(c2ccccc2)CC1)C(=O)NC1CCCC1 +Cc1cccc(C)c1NC(=O)c1sccc1SCC#N +CCC(=O)c1ccc2c(c1)N(CC(=O)NCC(C)C)C(=O)C(C)(C)O2 +C1COC2(CCN(c3nc(C4CC4)no3)CC2)O1 +COc1ccc2cc(C(=O)Nc3ccccn3)ccc2c1 +COC(=O)CCc1cc(OC)c(Cl)cc1OC +Cc1ccc(N2CC(C(=O)OCc3cc(C)no3)CC2=O)cc1 +OC1CC(c2ccncc2)C(NCc2ccccc2)C1O +Cc1cc(-c2cn(Cc3ccccc3)cc2N)on1 +Cc1ccc(=O)n(CC(=O)Nc2ccc(OCCC(C)C)cc2)n1 +Cc1ccc(NC(=O)Cc2csc(C)n2)c(Br)c1 +CC1CCc2sc(C(=O)Nc3cnn(C)c3)cc2C1 +O=C(COc1ccccc1)Nc1cccc2ncccc12 +COCCCNC(=O)c1ccccc1NC(=O)c1ccsc1 +CCCCCNC(=O)C1CN(C(C)=O)c2ccccc2O1 +CN(C)C(=O)c1ccc(CNc2cnn(-c3ccccc3)c2)[nH]1 +CCn1nc(C)c(C(C)NC(=O)Nc2ccc3ncccc3c2)c1C +COCCn1c(SC)nc2c(c1=O)SC(C)C2 +O=C(Cc1cccc(F)c1)N1CCN(Cc2ccncc2)CC1 +FC(F)(F)c1ccnc(-c2cccc3c2CCNC3)n1 +COC(=O)c1ccc(-c2noc(C3CCOCC3)n2)cc1 +CCOC(=O)CN(C(=O)c1ccoc1)c1ccc(F)cc1 +O=C(CCNC(=O)c1ccco1)Nc1cccc(Cl)c1F +CCc1ccc(C(=O)Nc2cc(N)ccc2OC)cc1 +CC(C)(C)NC(=O)C(C#N)Cc1ccc(Br)cc1 +CCC(C)C(NC(=O)c1ccccc1)C(=O)N1CCNC(=O)C1 +CNC(=O)N1CCCN(C(=O)CCc2ccccc2)CC1 +CCCCC(CC)Cn1cnc2c(cnn2C)c1=O +O=C(NCCOc1cccnc1)C1c2ccccc2Oc2ccccc21 +CCN(C(=O)c1ccc(Cl)c(N)c1)C1CCCC1 +Cn1cccc1C(=O)NCC1(C(N)=O)CCOCC1 +CCSc1nc(N)cc(-c2ccc(OC)c(OC)c2)n1 +Cn1sc(=O)c2cc(S(=O)(=O)NCCc3ccncc3)ccc21 +COCC(C)Nc1ccc(S(C)(=O)=O)cc1N +COc1ccc(Cl)cc1NC(=O)COc1ccc2c(c1)OCO2 +OCc1c(-c2ccncc2)nc2sc(-c3cccc(F)c3)nn12 +O=S(=O)(CCOc1ccccc1)c1ncccc1Br +COc1ccccc1C#CCNC(=O)Cn1cnc2ccccc2c1=O +CCCC(C)N1CC(C(=O)Nc2ccc(OC)c(F)c2)CC1=O +CC(CC(=O)NC1CCC(=O)NC1c1cccs1)n1cncn1 +Cc1csc(CCCNC(=O)c2c(C)cc(C)[nH]c2=O)n1 +Cn1ccc(CN2CCN(c3ccnc(-c4ccccc4)n3)CC2)c1 +O=C(CSc1ncc(C(F)(F)F)cc1Cl)c1ccc[nH]1 +COC(=O)Nc1cccc(NC(=O)NC(C)c2cc(C)sc2C)c1 +NC(=O)C1CN(Cc2cccc(OCc3ccc(F)cc3)c2)CCO1 +COCCCCCc1ncnn1-c1ccc(F)cc1F +COc1ccc(-c2ccnc3nc(C(F)(F)F)nn23)cc1 +Cc1ccc(SCC(=O)Nc2nccs2)cc1C +CCn1cc(NC(=O)NCC(Cc2ccc(F)cc2)C(N)=O)cn1 +CCNC(=O)c1cnc(-c2ccc(CC)cc2)nc1N +Cc1ccc(C)c(NC(=O)CSc2nc(C)c(C)o2)c1 +Nn1c(SCc2ccc3c(c2)OCO3)nnc1-c1cccnc1 +CCOc1ccc2c(C)c(CC(=O)OC)c(=O)oc2c1C +Cc1ccc(-c2nc(CC(=O)NCC3CCC3)cs2)o1 +COc1ccccc1OCCC(=O)Nc1ccc(N2CCCC2)nc1 +N#Cc1ccccc1CN1C(=O)OCC1C(=O)NC1CCOCC1 +Cn1c(C#N)cc(=O)c2cc(Br)ccc21 +CN(C)c1ccnc(CNC(=O)Nc2ccc3c(c2)OCO3)n1 +Cc1nc(CN(C)C(=O)c2cccc3c2ccn3C)nc2ccccc12 +Cc1noc(CC2COCC3CN(Cc4scnc4C)CC23)n1 +Cc1ccc(OC2CCN(C(=O)C3CC=CCC3)CC2)cn1 +NC(=O)C1Cc2ccccc2CN1Cc1ccc(-n2ccnc2)cc1 +COc1cc(CNC(=O)c2ccoc2)ccc1OCc1ccncc1 +N#Cc1ccccc1COc1ccc2sc(=O)oc2c1 +O=C(NCCc1ccsc1)C1CC(=O)N(c2ccccc2)C1 +CCC(=O)Nc1cccc(C(=O)N2CCCCC2CC)c1 +Cc1ccc(S(=O)(=O)N2CCCCC2C(N)=O)c(C)c1 +CCc1cc(=O)[nH]c2cc(NC(=O)c3csc(C)n3)ccc12 +Cc1ccc(-c2nnc(COc3cccc(-c4nnco4)c3)o2)cc1 +NC(=O)Nc1cccc(C(=O)Nc2cccc3cccnc23)c1 +CCCC1CN(C(=O)Nc2cc(F)ccc2C(=O)OC)CCO1 +CC1COCC(C)N1C(=O)c1[nH]c2ccccc2c1Br +CCC(C)c1cc(C(=O)N2CCCC(c3noc(C)n3)C2)on1 +NC(=O)NCc1ccc(NC(=O)C2C3CC4CC(C3)CC2C4)cc1 +O=C(c1n[nH]c2ccccc12)N1CCC(N2CCNC2=O)CC1 +O=C(Cc1cccs1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +COc1ccccc1C1CSc2nnc(C(C)(C)C)n2N1 +Clc1cnn(Cc2cccc3c2OCCO3)c1 +Clc1ccccc1-n1nccc1-c1ncccn1 +OC(CN1CCN(c2ccccc2)CC1)c1ccc(F)c(F)c1 +CC(Oc1c(Cl)cccc1Cl)C(=O)n1ccnc1 +Cn1ccc(-c2nc(CC(=O)NCc3ccccc3)no2)cc1=O +CN(Cc1cccs1)C(=O)Cn1ncc(Cl)c(Cl)c1=O +C=CCN(CC=C)C(=O)Cc1noc2c(C)c(C)c(N)cc12 +CC(C(=O)N1CCCN(C(=O)c2ccccc2)CC1)n1cccn1 +CN(CC(=O)NCC(F)(F)F)c1ccc(Oc2ccccn2)cc1 +Cc1oncc1C1NCCc2c1cc(F)c(Cl)c2F +CCOC(=O)c1sc(NC(=O)c2ccncc2)cc1C +Cc1c(C(=O)N2CCOCC2(C)C)cnn1C(C)(C)C +CN(C)c1ccc2c(c1)C(c1cc(F)cc(C#N)c1)NCC2 +CCc1ccc(C(=O)N2CCN(c3oc(C4CC4)nc3C#N)CC2)o1 +O=C(NCc1noc(C2CCCC2)n1)C1CCCC1 +Cn1cc(CCC(=O)N2CCC(C(O)c3ccccc3)CC2)cn1 +COc1cccc(C(=O)N2CCc3ccccc3C2)c1OC(F)F +O=C(Nc1ccccc1C(=O)NCc1ccccc1)c1cccs1 +CC(C)OCc1c(C(=O)NCCc2ccccn2)oc2ccccc12 +CCN(CC(C)C#N)C(=O)CCc1c(C)nc(SC)nc1C +COC(=O)CCCCNC(=O)c1cnc2[nH]nc(C)c2c1 +Cc1cccc(NC(=O)c2cccnc2)c1C(N)=O +CC(C)NC(=O)CCc1ccc(NC(=O)C2CC2)cc1 +COc1ccc2c(c1)CCN(Cc1coc(C(C)C)n1)C2 +O=C(Cc1ccccc1F)NC1CCCc2cn[nH]c21 +CCCNC(=O)c1cccc(CNC(=O)c2sccc2CC)c1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)C(C)c1cccs1 +O=C(Nc1cccc(NCc2cccc3cccnc23)c1)C1CC1 +COc1cc(CNc2cn(C)nc2C)cc(OC)c1 +CCCc1nnc(NC(=O)C2CC(=O)N(CCOC)C2)s1 +Cc1cnn(CCC(=O)Nc2ccc3c(c2)S(=O)(=O)C=C3)c1 +Cc1cc(=O)[nH]c(N2CCN(CC(=O)NCc3ccco3)CC2)n1 +N#Cc1ccc(N2CC3(CCN(C(=O)N4CCCC4)C3)CC2=O)cc1 +CCC1CCCCN1C(=O)CSc1ncc2ccccn12 +COC(=O)C(NC(=O)c1cc(C)n(Cc2cccs2)c1C)C(C)C +C=CCn1cnnc1SCc1nc(N)nc(N(C)C)n1 +Cc1c(C(=O)NCc2ccco2)sc2cccc(F)c12 +CN1CCN(C(=O)c2coc(COc3cccc(F)c3F)n2)CC1 +CN(Cc1ccco1)C(=O)CN1CCOC(C(N)=O)C1 +O=C(NCC#CCOc1ccc2c(c1)OCO2)c1ccc(=O)[nH]c1 +Cc1ccc(C(=O)NC2c3ccccc3CC2O)cc1C +Cc1cc(C)n(CC2CCN(S(=O)(=O)c3cccs3)CC2)n1 +COCc1noc(Cn2c(C)nn(C(C)(C)C)c2=O)n1 +CC(C)c1nn(C)c(N)c1-c1nc2ccccc2n1C +CC1(CNC(=O)c2ccc(N3CCCCC3)cc2)COC1 +COCc1cc(-c2cccc(OC(F)(F)F)c2)ncn1 +CN(CC(O)C1CC1)C(=O)C1COc2ccccc2O1 +O=C(Nc1ccc(CC(=O)N2CCCC2)cc1)c1cccs1 +CCCCc1cc(NC(=O)c2cc(C(C)C)[nH]n2)[nH]n1 +CN(Cc1cccc(C#N)c1)C(=O)CNC(=O)c1ccc(F)c(F)c1 +CCCC(=O)N1CCCCC1C(=O)Nc1c[nH]ccc1=O +O=S(=O)(Cc1cc(F)ccc1F)Nc1cnn(C2CCOC2)c1 +CN(Cc1ccccc1N1CCCC1)C(=O)NCc1ncn(C)n1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1cccn1C +O=C(COc1ccccc1NC(=O)C1CC1)NCc1cccs1 +COC(=O)c1cnc2c(c1)n(Cc1nncn1C)c(=O)n2CC(C)C +COC(=O)CNC(=O)Cc1cccc2ccccc12 +CC(Cc1ccc(O)cc1)NC(=O)Nc1ccc(-n2cccn2)cc1 +Nc1cc2c(cc1-n1nnc(-c3ccccc3)n1)OCCO2 +COc1ccc2onc(-c3ccc(C)c(N)c3)c2c1 +COc1cc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)ccc1C +Cc1cc(C)n2nc(SC(C)C(=O)NC(C)C)nc2n1 +CSc1ccc(C(=O)N2CCN(CCO)CC2)cc1 +COc1ccc(S(=O)(=O)N2CC(C(N)=O)CCC2C)cc1 +CC(=O)Nc1cccc(C(=O)Nc2cc(Cl)ccc2O)c1 +N#Cc1cccc(NC(=O)Cn2cnc(C3CCC3)cc2=O)c1 +O=C(NCCc1ccc(O)cc1)c1ccc(Cn2cccn2)o1 +CCNC(=O)Nc1cccc(Cl)c1OCCOC +CCOC(=O)CN(C)C(=O)c1cc(F)c(Cl)cc1Cl +CN(CCC(F)(F)F)C(=O)CCNC(=O)C(C)(C)C +CCc1ccc(S(=O)(=O)Oc2cccc(C(=O)N(C)C)c2)cc1 +N#Cc1cccc(C(=O)Nc2ncc(C#N)s2)c1 +O=C(Nc1ccc(OCc2ccccn2)c(Cl)c1)c1ccccn1 +CCOc1ccc2c(c1OC)C(c1ccccc1)NCC2 +Cc1[nH]c2cc(-c3cccnc3)nn2c(=O)c1CCO +Nc1nonc1-c1nnc(COCc2ccccc2)o1 +CCc1cc2c(c(C(O)c3ccccc3)c1)NC(=O)C2C +CNC(=O)Cc1ccc(-c2ccc(F)c(CO)c2)cc1 +Cc1cc(Cn2cnc3scc(-c4ccccc4)c3c2=O)no1 +COc1ccc(S(=O)(=O)NCCC(N)=O)cc1OC +CC1CN(C(=O)Cn2cnc3sccc3c2=O)C(C)CO1 +COC(=O)N(C)CC(=O)Nc1ccccc1SC(F)F +CCNS(=O)(=O)c1cccc(C(=O)NCC2CCCO2)c1 +CC(C(=O)Nc1ccc(Cl)cc1N)n1cccn1 +CN(Cc1ccsc1)C(=O)Cn1nnc(-c2ccccc2)n1 +COc1ccc2c(=O)n(CSc3nc4ccccc4o3)cnc2c1 +Cc1cc(C(C)NC(=O)Nc2nccs2)c(C)s1 +CCCOCC(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +O=C(Cc1ccc2c(c1)CCC2)Nc1ccc2c(c1)OCCO2 +CCOC(=O)NC1CCCN(CC(=O)Nc2c(C)nn(C)c2C)C1 +O=C(NC1CCN(c2ccc(F)cc2F)C1)c1scnc1C1CC1 +CC(C)OC(=O)CNC(=O)Nc1cccc(Cn2cccnc2=O)c1 +NC(=O)C1CCN(C(=O)Cc2noc3ccccc23)c2ccccc21 +CCCC(=O)N1CCC(C(=O)Nc2nncs2)CC1 +Cc1nc(C)c(CC(=O)N(C)CC(C)C)c(=O)[nH]1 +COCCCNC(=O)N1CCC(NC(=O)c2ccc(C)s2)CC1 +Cn1ccnc1SCC(=O)Nc1cc(N)ccc1F +Cc1nc(C(C)N(C)C(=O)Cc2c(C)nc(N)nc2C)c(C)s1 +NC(=O)c1ccccc1NC(=O)Cn1c(=O)[nH]c2ccccc2c1=O +Cc1nn(C)c(C)c1OC(=O)Cc1ccc(F)cc1F +Cc1ccc2c(c1)C(NC(=O)c1ccc(-n3ccnn3)cc1)CO2 +OCCn1ncc2c(NCc3cnn(-c4ccccc4)c3)ncnc21 +COC(=O)c1ccccc1NC(=O)CSc1nncs1 +Cc1cnn(CCC(=O)N2CCCC(c3noc(C(C)C)n3)C2)c1 +COC(=O)c1ccc(C(=O)NCCc2ccccc2F)cc1 +C1=C(CCNc2nnnn2-c2ccccc2)CCCC1 +COC1CCCCC1NC(=O)c1cnc2ccc(C)cn12 +CCOc1ccc(C(=O)N2CCc3ccccc32)cc1 +Cc1cc(C)n(CC(C)NC(=O)c2cc(-c3ccccc3F)n[nH]2)n1 +CCOC(=O)C1(NC(=O)c2ccc(-n3cncn3)cc2)CCCCC1 +O=C(Nc1ccc(-c2nnc3n2CCCCC3)cc1)c1cccnc1 +Cc1noc(CN(C)c2ccc(Br)cc2Cl)n1 +Cc1cccc2nnc(N3CCCC(C(=O)NCC(C)C)C3)n12 +CNC(=O)COc1ccc(-c2nn(C)c(=O)c3ccccc23)cc1 +CC(Sc1ccccc1)C(=O)c1c(N)n(C)c(=O)n(C)c1=O +Cc1nn(C)c(C)c1CC(=O)N1CCN(CCc2cccs2)CC1 +CCCCn1c(=O)c2ccccc2n2c(SCC#N)nnc12 +Cc1ccc(C(=O)N(CC2CCOC2)C2CC2)c(=O)[nH]1 +CCCCNC(=O)Nc1ccc2nc(C)sc2c1 +Cc1cc(-c2cnc(NC(C)C)nc2-c2ccc(C)o2)on1 +Cc1c(N)cccc1NC(=O)CSc1ccc(F)cc1 +Cc1sc2ncnc(NCCCO)c2c1-c1ccc(F)cc1 +O=C(NCCCN1CCOCC1)NCc1cccc2ccccc12 +COC(=O)C(NC(=O)C1CC(=O)Nc2ccccc21)C(C)C +COc1cc(C)ccc1OCC(=O)NCCc1c[nH]c2ccccc12 +Nc1ccccc1NC(=O)COc1ccc2ccccc2c1 +CCC(C)NS(=O)(=O)c1ccc(F)c(Cl)c1 +CCCC1(CO)CCCN(C(=O)Cc2c(C)[nH]c(=O)[nH]c2=O)C1 +CCC(NC(=O)c1cccc(OC)c1F)c1c(C)nn(C)c1C +CC(C)C1Oc2c(N)cc(Br)cc2N(C)C1=O +COC(=O)c1cccc(C(=O)Nc2cccc3cnccc23)c1 +CCc1nnc(NC(=O)c2nn(-c3ccccc3)nc2C)s1 +CC(C(=O)NC1CC1)N1CCSc2ccc(N)cc21 +Brc1ccc2oc3c(c2c1)CCNC3 +CCCNC(=O)COc1c(C)cccc1C(=O)NCC +O=C(NCC(=O)N1CCCC1c1ccc(F)cc1)c1cccc(F)c1 +CN(CCN(C)C(=O)c1cc2occc2[nH]1)C(=O)OC(C)(C)C +CC(=O)c1ccccc1OCCOc1ccc(-n2cnnn2)cc1 +Cc1nc2nnc3c(=O)n(-c4ccc(C(C)C)cc4)ccc3n2n1 +O=C(c1ccncc1F)N(Cc1ccc(Cl)c(Cl)c1)C1CC1 +C=CCN(Cc1ccccc1)C(=O)c1cc(C(C)C)nc2onc(C)c12 +Fc1ccc(-n2cc(-c3noc(-c4ccccn4)n3)nn2)cc1 +COc1cccc(C(=O)N(C)CC(=O)Nc2cc(C)ccc2C)n1 +O=C(Nc1cccc(OCC(F)(F)F)c1)N1CCCC1CO +NC1=NC(=O)C2C(=N1)NC(=O)CC2c1ccc(F)cc1 +Cc1nc(C(=O)N2CCN(C(C)C)CC2)nn1-c1ccc(F)cc1 +Cc1cnc(NC(=O)CNC(=O)N2CCc3ccccc3C2)s1 +Cc1onc(C=Cc2cc(Br)ccc2F)c1N +Cc1cccc(CNC(=O)NC(C)c2ccc(F)c(Cl)c2)n1 +O=S(=O)(c1ccc2ccccc2c1)N1CCCC1 +CC(C)OCCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +Cc1c(C(=O)Nc2cc(F)cc(F)c2)nnn1-c1ccccc1 +CCCN(C)C(=O)c1ccc(NC(=O)NC(C)C)cc1 +Cc1nn(C)c(C)c1CCCNC(=O)c1c(O)cccc1O +Cc1ccc(CCC(=O)NC2CCC(=O)CC2)cc1 +CCOC(=O)CC1CCCCN1C(=O)c1ccc(OC(F)F)cc1 +N#Cc1ccccc1NC(=O)CCc1cccc(F)c1F +CC(C)(NC(=O)c1ccc(-n2ccnc2)nc1)c1cccc(F)c1 +CC(C)c1cccc(NC(=O)CSc2nc(N)cc(N)n2)c1 +Cc1ccc2c(c1)oc(=O)n2CCCOc1cccc(N)c1 +C=CCN(Cc1cccc(C#N)c1)C(=O)NC(C)c1c(C)noc1C +Cc1cnn(C2CCCN(C(=O)Cn3ccc(=O)n(C)c3=O)C2)c1 +COc1cc(NC(=O)N2CCCC2CO)c(OC)cc1Cl +CCc1ccc(OCC(=O)Nc2nnc(C3CCCO3)s2)cc1 +CCCCS(=O)(=O)Nc1cc(N)c(F)cc1F +Cc1ccc(-n2cnnc2)cc1NC(=O)NC1COC2(CCCC2)C1 +O=C(NCCNc1ccc(C(F)(F)F)cn1)C1CC=CC1 +O=C(CNc1cc(Cl)ccc1N1CCOCC1)N1CCOCC1 +Cc1occc1C(=O)NC(C)Cc1c(F)cccc1F +Cc1cccc(OCCC(=O)N2CCCC(O)C2)c1C +CC(=O)Nc1ccc(C(=O)OCC(=O)Nc2ccccc2C)cc1 +COc1ccc(NC(=O)Cn2ccc(=O)n(C)c2=O)cn1 +COc1ccc(-c2cncc(C(=O)NC3CC3)c2)cc1 +O=C(NCc1cc(F)ccc1Br)C1CC1c1ccco1 +CCN(CC(=O)NC(C)C)C(=O)c1oc2c(OC)cccc2c1C +COC(=O)c1ccccc1NC(=O)Cc1csc(C)n1 +O=C(CCc1nc2ccccc2[nH]c1=O)OCc1cccc(Cl)c1 +O=C(c1ccnn1-c1ccc2ccccn12)N1CCOCC1 +Cc1ccc(CN2CC(C(=O)N3CCN(C)CC3)CC2=O)cc1 +CCC(CC)C(=O)Nc1cccc(C(=O)Nc2nccc(C)n2)c1 +COc1ccccc1NC1CCN(C(=O)c2ccc[nH]2)CC1 +CC(C)(C)c1ncc(NC(=O)c2ccn(-c3ccccc3F)n2)cn1 +COc1ccc(C)cc1NC(=O)CNc1cc(C(N)=O)cc(F)c1C +Cc1ccc(NCc2nnc(C(C)(C)C)o2)cc1Br +O=C(CCSc1ccc(F)cc1)Nc1ccc2c(c1)NC(=O)CO2 +CCC(=O)c1cc(Br)cc(Cl)c1O +CC1CCCC(C)N1C(=O)CSc1ncnc2ccccc12 +Cn1cnnc1SCCOc1ccc(C#N)cc1 +CNC(=O)C1CC2CN(C(=O)NC3CCCCCC3)CC1O2 +O=C(CC1CCCC1)NCCC1CCN(C(=O)c2ccccc2)CC1 +Cc1c(C(=O)NC(C)(C)C)nnn1Cc1ccccc1 +Cc1ccc(-c2n[nH]cc2C2NC(=O)c3n[nH]c(C)c3N2)o1 +N#Cc1ccc(NC(=O)c2nc3ncc(Br)cn3n2)cc1 +COc1ccc(CC(=O)NC2CCCc3ccccc32)cc1 +COc1cccc(NC(=O)NCc2nc(-c3ccccc3)no2)c1 +O=C(NCCCO)Nc1ccc(OCC(F)(F)F)cc1 +CC(NC(=O)c1ccccc1N(C)S(C)(=O)=O)c1ccccc1 +COC(=O)C(C)(C)NC(=O)c1sc(-c2ccccn2)nc1C +CCN(CC)C(=O)CN1C(=O)COc2ccc(Cl)cc21 +CN(C)C(=O)C1CCN(C(=O)c2cccc(S(C)(=O)=O)c2)CC1 +Cc1cccc(C(=O)c2ccc(OCC(N)=O)cc2)c1 +CCc1noc(CC)c1CC(=O)NC1CCc2ccccc21 +COC(C)(CNS(C)(=O)=O)c1cccc(Cl)c1 +Cc1nonc1C(=O)NC(C)C(O)c1ccccc1 +Cc1ccc(C(C)NS(=O)(=O)c2c[nH]cn2)cc1F +CCC(=O)NC(Nc1cccc(C)n1)(C(=O)OC)C(F)(F)F +CC1NCc2ccccc2C1NC(=O)c1cccs1 +COC(=O)c1sc2c(cnc3c(F)cc(F)cc32)c1N +CCOc1ccc(CN(C)C(=O)C2CC=CCC2)cc1 +OC(CNCc1ccco1)c1ccc(F)c(F)c1 +CC(C)Sc1ccc(Cc2nnc(NC(=O)C3CC3)o2)cc1 +Cc1ccc2sc(NC(=O)c3ccn(C)n3)nc2c1C +Cc1ccc(C(=O)N2CCC(C)(O)C(O)C2)s1 +O=C(c1cnc(C2CCCO2)s1)N1CCOCC1 +O=C(Nc1ccc2c(c1)OCO2)Nc1nnc(-c2ccco2)o1 +CC(C)c1ncc(CNC(CC(F)(F)F)c2ccc(F)cc2)s1 +COc1cccc(COC(=O)Cn2nc3ccccn3c2=O)c1 +CN1C(=O)C(C)(C(=O)NCCCO)Sc2ccccc21 +Cc1cc(C)cc(OC(=O)c2ccc(C(N)=O)nc2)c1 +CCOCc1ccc(CNS(=O)(=O)c2cn[nH]c2)cc1 +COCc1ccccc1C(=O)OCc1cccc(F)c1 +Cc1cc(C)n(CC2CCN(C(=O)c3ccc4ccccc4n3)CC2)n1 +CCn1c(SCC(=O)Nc2ccnn2C(C)C)nnc1C1CC1 +Cn1cnnc1SCC(=O)c1ccc(Oc2ccccc2)cc1 +Cc1ccc2c(c1)CN(C(=O)OC(C)(C)C)C(C)CN2 +Nc1cc(NC(=O)COCc2ccco2)ccc1F +CC(NC(=O)c1ccco1)C(=O)N(C)CCC(F)(F)F +COc1cccc(CNc2ccccc2C(N)=O)c1 +O=C(NC1CCCc2occc21)c1ccc(Br)cn1 +O=C(CSc1nc2ccccc2o1)Nc1cccc2cccnc12 +O=C(NCCc1ccc(F)cc1F)c1n[nH]c(=O)[nH]1 +CCCCOC(=O)c1ccc(NC(=O)c2cn(C)nn2)cc1 +COC(=O)Cn1c(=O)c2ccccc2n(CC(=O)OC)c1=O +CN(CC(N)=O)C(=O)Cn1c(=O)cnc2ccccc21 +CC(=O)NCCC(=O)NC(C)Cc1c(F)cccc1F +Cc1noc(C(C)Oc2ccccc2Br)n1 +O=S(=O)(N1CCCCCC1)N1CCN(c2ncccn2)CC1 +CC1CCCCC1Nc1ccc(S(C)(=O)=O)cc1S(C)(=O)=O +NC(=O)C1CCN(C(=O)Nc2ccc(Cl)c(Cl)c2)C1 +C=CCn1c(SCC2(CO)COC2)nc2sccc2c1=O +COc1ccc(Br)cc1-c1c(N)c(C)nn1C +COCCn1ccc2ccc(NC(=O)N(C)C(C)CC#N)cc21 +Cc1ccc(-c2noc(-c3cccn4c(=O)[nH]nc34)n2)cc1 +N#CCCC(=O)Oc1ccc(Br)cc1 +Cc1cc(C)c(NC(=O)c2ccc(CN3CCCC3=O)cc2)c(C)n1 +COc1cc(OC)c2c(c1)C(C(O)CO)NCC2 +COc1ccc(C(NC(=O)c2ccncc2)C2CCOCC2)cc1 +COc1ccc(CNc2ncnc3sc4c(c23)CCC4)cc1F +COc1cccc(C(=O)c2c(N)c(C(N)=O)c3ccccn23)c1 +CCC1CN(C(=O)c2cc(Cl)c3c(c2)OCCCO3)CCO1 +Cc1cc(C)c(CCN(C)S(=O)(=O)CCCO)c(C)c1 +Cc1nn(C)c2sc(C(=O)N(C)Cc3cccc(Cl)c3)cc12 +COC(=O)c1sc(NC(=O)Cc2cccc(OC(C)C)c2)nc1C +CC(C)CC(=O)N1CCc2nc(NC(=O)c3ccco3)sc2C1 +C#CCN1CCC(C(=O)NC2CCN(c3c(F)cccc3F)C2)CC1 +CCc1cc(NC(=O)CCSc2ccc(C#N)cc2)[nH]n1 +CCOC(=O)N1CCC(C(=O)Nc2nc(C)cs2)CC1 +Cc1nnc(NC(=O)CCCOc2ccc(Cl)cc2)s1 +CC(NC(=O)CCn1nc(-c2ccccc2)ccc1=O)c1ccccc1 +CCOC(=O)CN(C(=O)Nc1ccccc1OC)C(C)C +Cc1n[nH]cc1CNCC1CCCc2ccccc21 +CCc1ccccc1OCC(=O)NCC(=O)Nc1cn[nH]c1 +Cn1c(SCC(=O)NC2CCCCCC2)nnc1-c1ccncc1 +Cc1cc(N)nc(COc2ccc(Cl)cc2Cl)n1 +O=C(NCC1CCOC1)Nc1ccc(Cl)cc1 +Cc1cccc(NCC(O)Cn2nnnc2-c2ccccc2)c1 +COc1cccc(CNC(=O)c2cnc(Cc3ccccc3)s2)c1 +N#Cc1ccccc1Oc1ccc(NC(=O)Cn2cccn2)cc1F +Cc1ccccc1-n1c2c(c(=O)[nH]c1=O)CN(Cc1ccccc1)CN2 +Cc1cc(F)ccc1NC(=O)NC1CCN(c2ccccc2)C1=O +Cc1ncc(C(=O)N2CCOC(c3ccccn3)C2)cn1 +Cc1nn(CC(=O)Nc2cnn(C(C)(C)C)c2)c(C)c1Cl +CCc1ccc(NC(=O)Nc2cc(C)nn2C)cc1 +CC1(C(=O)NCC(=O)NCc2ccccc2)CC1(Cl)Cl +CC(C)(C)OC(=O)NCc1nc2cc(Cl)ccc2[nH]1 +O=C1CSc2ccc(NCc3ccccn3)cc2N1 +Nc1cc(F)c(NCCCN2CCOCC2)c(F)c1 +COc1ccc(OC)c2c1c(=O)c1ccccc1n2C +O=C(COC(=O)CSc1ccccc1F)NC1CCCCC1 +COc1cccc(C2NCCc3cc(O)c(OC)cc32)n1 +O=C(Nc1ccc(S(=O)(=O)C(F)F)cc1)c1ccsc1 +O=C(NCCCCn1cnnc1)c1ccc(Br)c(O)c1 +Cc1cc(-c2nnc(NC(=O)CSc3ccccc3)o2)n(C)n1 +Cc1nn(C)c(C)c1NC(=O)CSc1nnc2n1CCCCC2 +Cc1ccccc1NC(=O)Cn1nc(C)c(Cl)c1C +CCC1COCCN1C(=O)NCc1cn(-c2ccccc2)nn1 +CC(C)=CC(=O)Oc1cc2ccccc2cc1C(=O)N1CCOCC1 +COc1ccccc1C#CCNC(=O)C(C)Oc1ccccc1 +Cc1ccn2cc(C(=O)NCc3ccc(Cn4cccn4)cc3)nc2c1 +CNC(=O)c1c(NC(=O)c2ccccc2)sc(C)c1C +Cc1cc(C(=O)N2CCC(C)CC2)ccc1NC(=O)NC1CCCC1 +O=C(COC(=O)c1cccnc1)Nc1ccc(F)cc1 +Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)NCc1cccs1 +CCc1nnc(SCC(=O)Nc2cccc(Cl)c2)n1N +Cc1cccc(C(=O)N2CCN(CC(C)O)CC2)c1 +CN(CC(=O)NCc1ccnc(OC2CCC2)c1)c1ccccc1 +Cc1cccc(-n2nc(C)nc2-c2cc(S(N)(=O)=O)ccc2F)c1 +COc1ccc(C(CC(=O)NCc2ccco2)n2cccc2)cc1 +O=C(OCc1noc(-c2ccco2)n1)C1CC2CCCC(C1)C2=O +Cc1ccc(N2CCN(c3nc(C)cc(C(F)(F)F)n3)CC2)nn1 +COc1ccc(C(C)NC(=O)COc2ccccc2F)cc1 +Cc1ccc(-c2nn(-c3ccccc3)cc2CO)cc1 +O=C(Cc1ccc2c(c1)OCO2)Nc1nnc(C2CCCCC2)o1 +CC(C)Cc1cc(C(=O)NC(C)c2nc(CC(C)C)no2)n(C)n1 +CC(O)CCN(C)C(=O)Nc1ccn(-c2ccccc2)n1 +CCC(=O)OCc1ccc(-n2nc(C)cc2C)cc1 +Cc1ccsc1CNC(=O)CCc1ccsc1 +COCC(=O)Nc1cccc(S(=O)(=O)NC2CC2)c1C +COC(=O)Nc1cc(NC(=O)c2c(F)cccc2Cl)ccc1F +Cc1nc2ccccc2nc1Cn1nc(-c2cccs2)oc1=O +Cc1ccc2nc(C(F)(F)F)nc(NCc3cccnc3)c2c1 +COc1cccc(-c2nc3ccc(C)cn3c2C(C)O)c1 +COC(=O)Cn1ccn(-c2cccc(Cl)c2)c(=O)c1=O +O=C(CSc1nncn1C1CC1)NC1(c2ccccc2)CCC1 +CC(CNC(=O)C1COc2ccc(F)cc2C1)N1CCOCC1 +O=C(CSc1nnnn1-c1ccccc1)OCc1ccccc1 +COc1cc(Cl)ccc1CNS(=O)(=O)c1cnn(C)c1 +CN(CCC#N)C(=O)CSc1nnc(-c2ccc(Cl)cc2)o1 +COc1ccc(-n2nc3cc(N)c(Br)cc3n2)cc1 +Cc1occc1-c1nnc(Sc2ncnc3sccc23)o1 +C=CCCC(=O)Nc1cc(S(N)(=O)=O)cc(C)c1C +Cc1nc2ccccc2n1CCNC(=O)C1CC1c1ccco1 +COC(=O)c1ccc(C)c(NS(=O)(=O)c2ccc(C(C)=O)cc2)c1 +O=c1ccc(-c2ccco2)nn1CCNS(=O)(=O)c1cccnc1 +Cc1cccc(NC(=O)N2CCN(c3cnccn3)CC2)n1 +Cn1ccc(C(=O)Nc2nnc(-c3ccc4c(c3)CCCC4)o2)n1 +CNC(=O)Cn1ccnc1Cc1ccccc1C(F)(F)F +Cc1cccc(CN(C(=O)C(C)NC(=O)c2ccoc2)C2CC2)c1 +Cc1ccc(N)c(C(=O)Nc2ccc(Cl)cc2)c1 +CC(C1CC1)N(C)C(=O)NCc1nnc2ccccn12 +CCOC(=O)NC1CCCN(C(=O)c2ccccc2F)C1 +CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCCO1 +CNC(=O)c1cccc(NC(=O)c2cn[nH]n2)c1C +CCn1nc(NCc2ccc3c(c2)OCO3)cc1C +O=C1CCC(NC(=O)COc2ccc(Cl)cc2)CN1 +CC(C)(C)OC(=O)NCCCC(=O)Nc1cccnc1 +COc1cc2nc(C(C)C)n(CCO)c2cc1OC +N#CCCC(C#N)Cn1cnc2c(cnn2-c2ccc(F)cc2)c1=O +CN(C)C(=O)c1cccc(NCC(=O)NC(C)(C)C)c1 +Cc1nc(NCCCN2CCOCC2)cc(-c2ccc(F)cc2)n1 +Cc1ccc(C(N)=O)cc1OC(=O)Cc1cccc(F)c1F +COc1ccc(CNc2nccn(-c3ccc(F)cc3)c2=O)cc1 +Cc1ccc(S(=O)CC(=O)NCC2CCCCC2)nc1 +COc1cc(F)ccc1NC(=O)NC1CCCc2c1cnn2CCO +COC(=O)c1ccc(S(=O)(=O)Nc2ccccn2)c(C)c1 +COc1cccc(C(=O)Nc2ccc(C)cn2)c1OC +Cc1ccc(C(=O)Nc2nc(-c3ccccn3)cs2)cc1 +O=C(Nc1cccc(Br)c1)c1cc2n(n1)CCCO2 +O=C(NCC(O)COc1cccc(F)c1)c1ccccc1O +CCOC(=O)c1cn[nH]c1S(=O)(=O)Nc1ccc(F)cc1 +CC(C)N(CC1CC2C=CC1C2)C(=O)c1ccc(-n2cncn2)cc1 +CC(C)COC1CCN(C(=O)NCCc2nccs2)CC1 +O=S(=O)(NCC1(c2cccs2)CCOCC1)C1CCCCC1 +Cc1nnc2ccc(SCC(=O)Nc3ccc(Cl)cc3)nn12 +CCOc1ccc(C(O)Cc2ccc(OC)cc2)cc1 +CN(Cc1ccccn1)C(=O)c1cc(Cl)cn1C +O=C(c1ccccc1)C1CCN(C(=O)c2ccc[nH]c2=O)CC1 +OC(CN1CCN(Cc2cccnc2)CC1)c1cccs1 +NC(=O)COc1cccc(CN2CCOC(Cn3cccn3)C2)c1 +Cc1ncsc1COC(=O)C1CCCN1C(=O)OC(C)(C)C +CCCOCC(=O)N1CCN(C(=O)c2n[nH]c3ccccc23)CC1 +CCCC(=O)Nc1cc(NC(=O)c2ccc3c(c2)OCO3)ccc1F +COC(=O)C(NC(=O)OCc1ccccc1)=C1COC1 +Cc1cc(OCC(=O)NCCCO)c2c(C)c(C)c(=O)oc2c1 +O=C(Cc1ccc[nH]1)NCC1(c2ccc(F)cc2)CCOCC1 +Cc1ccccc1OCC(=O)NCC(O)(c1ccccc1)C1CC1 +CN(Cc1ccc(OC(F)F)cc1)C(=O)c1ccc(O)c(Cl)c1 +COc1cc(Cl)ccc1C(=O)N1CCCC(n2nc(C)nc2C)C1 +COc1ccc(Cn2c(=O)[nH]cc(F)c2=O)cc1Cl +NC(=O)c1cccc(NC(=O)Cc2csc(-c3cccs3)n2)c1 +CCc1nnc(Cn2cnc3sc(CC)cc3c2=O)o1 +CCc1nnsc1C(=O)N(C)CCOc1ccc(Cl)cc1 +N#Cc1ccccc1COC(=O)c1c[nH]c2ccccc12 +CCc1c(C(=O)NC2CCCC(C)C2)[nH]c(C)c1C(C)=O +COc1cccc(C(CNC(=O)Cc2c(C)noc2C)OC)c1 +Cc1cc2ncc(C(C)NCc3nncn3C)c(C)n2n1 +Cc1nc2ccc(C(=O)N(C)Cc3ccc(C4CC4C)o3)cc2nc1C +CC1C(=O)Nc2c(F)cc(C(O)c3cccc(Cl)c3)cc21 +Cc1cc(C)cc(COCCOCn2c(C)c(C)c(=O)[nH]c2=O)c1 +CCCCN(C(=O)c1ccco1)c1c(N)n(CC(C)C)c(=O)[nH]c1=O +Cc1noc(C)c1CC(C)NC(=O)N(C)CC(F)F +O=C(NC1CCCCNC1=O)c1cn(Cc2ccc(F)cc2)nn1 +CC(c1ccc(Cl)cc1)N(C)C(=O)CSc1nncn1C +O=c1[nH]nc(SCc2cccc(F)c2)n2nc(-c3ccco3)cc12 +O=S(=O)(c1cccc2ccccc12)n1cccn1 +CCN(C(=O)CCOC(C)C)c1cc(C)cc(C)c1 +CC1=Nn2c(Cc3ccccc3F)nnc2SC1C(=O)N(C)C +Cc1cc(C(=O)NCC(O)c2ccco2)c2cnn(C(C)C)c2n1 +CCOc1cc(C#N)ccc1OCC(=O)c1cnn(C)c1 +Cc1cc(NC(=O)CNc2ccccc2OCC2CC2)n(C)n1 +CC(C)NC(=O)Cc1ccc(S(=O)(=O)N2CCCCC2)cc1 +Cc1cc(C(=O)NC(C)Cn2cccn2)c(C)s1 +COC(=O)NC(C(=O)Nc1cc(C(N)=O)n(C)c1)C(C)C +Cc1cccc(-n2ncc(C(=O)NCCCN3CCOCC3)c2C)c1 +Cc1nnc(NC(C)c2ccc(-n3cncn3)cc2)c(C#N)c1C +COc1cc(-c2ccnc3nncn23)cc(OC)c1OC +CCOCCNC(=O)Nc1ccc(Br)cc1Cl +CC(=O)Nc1ccc(Nc2ncnc(NC(C)(C)C)c2N)cc1 +CC(Sc1nccn1C)C(=O)c1c[nH]c2ccccc12 +COCCc1noc(-c2cn(Cc3ccccc3F)nn2)n1 +CCc1nc2nccc(-c3ccccc3Cl)n2n1 +Cc1sc(=O)n(CC(=O)NCc2nc3ccccc3s2)c1C +O=C(Nc1ccc(N2CCOCC2)cc1C(F)(F)F)C1CC=CC1 +CCOC(=O)N1CCC(NC(=O)c2cccc(COC)c2)CC1 +CCC(NC(=O)Cn1ccc2ccccc21)C1CCOCC1 +CC1CCC(C(N)=O)CN1c1nccc(C(F)(F)F)n1 +Nc1cc(F)cc(N(CCO)C2CCCCC2)c1 +NC(=O)Cc1ccc(NC(=O)c2ccccc2-c2ccccc2)cc1 +Cc1noc(C)c1C(C)C(=O)NC1CCN(c2c(F)cccc2F)C1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCCc1ccc2c(c1)OCO2 +O=C(CCCn1cncn1)Nc1c[nH]cc(Br)c1=O +Cc1ccc(NCc2nnc(C3CC3)o2)cc1OC(F)F +O=C(Oc1ccc(-n2cnnn2)cc1)C1(c2ccc(F)cc2)CC1 +NS(=O)(=O)N1CCN(C(=O)CC(F)(F)F)CC1 +O=C1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1 +CC(NC(=O)NCCCn1cccn1)c1nncn1C +Cc1cc(SCC(=O)NCCO)c(C)cc1Br +COCC(C)(O)CNS(=O)(=O)c1ccc(Cl)cc1 +COCc1nc(C(=O)Oc2cccc(C(C)=O)c2)cs1 +CCOc1ccc(OCC)c(S(=O)(=O)N2CCCCC2C)c1 +COC(=O)Cc1cccc(-c2nn3cnnc3s2)c1 +CCOC(=O)N1CCN(CC(=O)Nc2cccc3ccccc23)CC1 +Cc1n[nH]cc1Nc1ncc(C(F)(F)F)cc1Cl +COc1ccc(-c2ccnc3nc(-c4ccco4)nn23)cc1 +Cc1noc(CN2CC(c3ccccc3C)CC2C)n1 +CN(C)c1ccnc(CNC(=O)c2c(F)cccc2Cl)n1 +CC(C(=O)N1CCN(c2ccccc2)CC1)c1ccsc1 +COC1CCN(C(=O)c2ccc(C)cn2)CC1Cc1ccccc1 +CCc1nc(CNc2cccc(C(=O)OC)c2)no1 +COc1cc(F)ccc1NC(=O)c1cccnc1OC +CCCS(=O)(=O)c1cc(N)cc2c1ccn2C +CCC(C)C(=O)Nc1cc(C)n2nc(C(F)(F)F)nc2n1 +Cn1nc(C(C)(C)C)cc1C(=O)N1CCCCC1CN1CCOCC1 +O=C(Nn1cnnc1)c1cc2ccccc2n1Cc1ccccc1 +CC(=O)Nc1cccc(C(=O)Nc2ccc(OC(F)F)c(F)c2)c1 +CCNc1nc2c(c(=O)n(C)c(=O)n2C)n1C(C)C +CCCC(=O)NC1CCN(c2c(F)cccc2F)C1=O +CCC(CC)C(=O)NCCNc1cccc(F)c1C#N +OCCCNc1ncc(-c2ccc(OC(F)(F)F)cc2)cn1 +CN(C)C(=O)c1ccc(CN2CCOC(c3cccs3)C2)[nH]1 +COCc1nc(C(=O)N2CCCC(c3ccccc3)CC2)cs1 +CCCn1ncc(C(=O)NCc2ccc(-c3noc(C)n3)cc2)c1C +O=C(Cn1nnc(-c2ccncc2)n1)NCCc1ccccc1 +Nn1c(SCC(=O)c2ccc(NC(=O)C3CC3)cc2)nncc1=O +CN(Cc1nnc2n1CCC2)C(=O)c1ccc2c(c1)CCCC2 +COC(=O)CNC(=O)C1CCN(c2cc(C)cc(C)c2)C1=O +O=C(CN(Cc1cnc2cnccn12)CC1CCCO1)N1CCCC1 +N#Cc1ccc(OC2CCC(NC(=O)CN3CCOCC3)CC2)nc1 +CS(=O)(=O)c1ccc2nc(-c3cccs3)[nH]c2c1 +O=C(NC1CCN(C(=O)C2CC2)C1)c1ccc(F)cc1 +C#CCN(Cc1ccco1)C(=O)NCC1CCCC1 +Nc1ccc(S(=O)(=O)NC2CCN(CC(F)(F)F)C2)cc1 +CC(=O)Nc1cccc(-c2nccn2CC2COC(C)(C)O2)c1 +CCc1ccccc1NC(=O)CCn1ccc(C)n1 +Cc1cc(S(=O)(=O)NCc2cccnc2)cc2c1NC(=O)C2(C)C +CC(C)C(=O)Nc1ccc(CNS(=O)(=O)Cc2ccccc2)cc1 +N#Cc1ccc(Cl)cc1NC(=O)Cn1nnc2ccccc2c1=O +CC(=O)NC(C(=O)NCC1CCC(C)(C)CC1)C1CCCC1 +CCN(CC(C)(C)O)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +O=C(NCCCN1CCOCC1)c1cnc(-c2ccccc2)s1 +CC1CCC(n2c(=O)[nH]c3ccsc3c2=O)CC1 +CN(C)c1cccc(C(=O)NCCn2ccnc2-c2ncccn2)c1 +O=C(NCc1noc(-c2ccco2)n1)NCC1CCC1 +O=C(NCCN1CCOCC1)c1nnc(-c2ccc3c(c2)OCO3)o1 +CC(C)c1noc(CCC(=O)Oc2ccc3c(c2)CCC3)n1 +Cc1ccn(CC(=O)Nc2ccc(C(F)(F)F)cc2)c(=O)c1 +N#Cc1ccc(NCC(=O)OCc2cn3ccccc3c2C#N)cc1 +COc1ccc(NC(=O)C2CCCC2)cc1N1CCCCC1=O +Cc1cccc(C)c1NC(=O)C(C)Cn1nc(C(F)(F)F)cc1C +NC(=O)CC1CCN(C(=O)c2ccc(OC(F)F)cc2)CC1 +COc1cc(CNC(=O)c2c(C)nn3c(C)cc(C)nc23)ccn1 +Cc1cc(C(=O)NC2CCCc3occc32)c2ccccc2n1 +CCOC(=O)CCN1CCN(C(=O)c2ccc(C)s2)CC1 +CN(C)CC1NCCc2cccc(OC(F)(F)F)c21 +CC(C)N(Cc1cnn(C)c1)C(=O)c1cc(C2CC2)nc2ccccc12 +O=C(CCNC(=O)NCc1ccccc1)Nc1ccccc1F +CCOc1ccc(S(=O)(=O)NCC(C)(O)C2CC2)cc1F +Cc1noc(C)c1CCC(=O)N(CCC#N)Cc1cccnc1 +Cc1nc(NCC2CCN(S(C)(=O)=O)C2)nc(C)c1CC(C)C +COC(=O)C(Cc1c(C)cc(C)cc1C)NC(C)=O +Cc1csc(NC(=O)C2CCC(=O)N(C)C2c2cccs2)n1 +OCCCn1c(-c2cccc(O)c2)nc2ccccc21 +CCc1c(C(=O)N(CC)CCO)cnn1-c1ccc(C)cc1 +CN1CCOCC12CCN(C(=O)Cc1ccsc1)CC2 +O=C(NCCc1c[nH]c2ccc(O)cc12)c1ccc(Cl)cc1 +Nc1c(NC2CCCCC2O)ccc2scnc12 +O=C(NCc1cccnc1)c1ccc2c(c1)CCCC2 +Cc1nn(C)c(C)c1CNC(=O)Cn1ccc2c(C)cccc21 +COC(C(=O)N1CCC(C)CC1C)c1ccccc1 +Cc1nc[nH]c1-c1nccn1CCCN1CCCc2ccccc21 +CN(C)S(=O)(=O)c1cc(NC(=O)c2ccccn2)ccc1Cl +CCCc1c(C(=O)OCC)cnn1-c1ccccc1 +CN1C(=O)CCc2cc(C(=O)N3CCCCC3)ccc21 +COc1ccc(Br)cc1NC(=O)NC(C)C +CCCCN1C(=O)COc2ccc(NC(=O)C(C)C)cc21 +CC(C)CCc1noc(CSc2nnnn2C)n1 +O=C(COc1cccc2cccnc12)NC1CCOCC1 +Nc1cc(Cl)ccc1NC(=O)CCCN1CCOCC1 +CCc1ccc(S(=O)(=O)N2CCC(n3cccn3)CC2)s1 +COc1ccc2c(c1)OC(C)CC2=CCC1(C)C(=O)CCC1=O +CSc1nc2oc3ccccc3c(=O)c2c(=O)n1C +Cc1cc(C(=O)N2CCC(c3nn(C)c4ncccc34)CC2)on1 +CC(NC(=O)c1cnn2ccn(C)c12)C1=CCCCC1 +CC1(C)C(=O)NCCN1S(=O)(=O)c1cccc(Br)c1 +CN(Cc1ccccc1)C(=O)COC(=O)c1ccc(Cl)c(N)c1 +CCNc1nnc(SC(C)c2ccc(C(=O)OC)o2)s1 +Cc1cc(C)cc(C(=O)OCC(=O)c2ccc[nH]2)c1 +O=C(CSc1ccncc1)OCc1cccnc1 +Oc1cccc2c1CCNC2c1cnccc1Cl +Cc1cc2nccc(-c3ncc(C(F)(F)F)cc3Cl)n2n1 +Cn1cc(-c2nc(C(=O)NCCC3CC4CCC3C4)cs2)cn1 +COc1ccc(NC(=O)COc2ccc(C)c(C)c2)cn1 +CC(=O)NCCNC(=O)CCc1c(C)nc2ncnn2c1C +O=C(Nc1cc(F)ccc1Cl)C1COc2ccccc2O1 +Cn1ccc2c(C(=O)Nc3ccc(Cl)c(C(N)=O)c3)cccc21 +CCOC(=O)Nc1ccc(C(=O)N(C)C2CCCCC2)cc1 +COC(=O)c1cc(CN2CCN(CC(F)(F)C(F)F)CC2)c[nH]1 +O=C(CCc1ccncc1)Nc1ccc(-n2cnc3ccccc32)cc1 +O=S(=O)(Nc1ccon1)c1cc(F)ccc1F +COCC1CN(C(=O)c2ccoc2C)Cc2cnn(C)c21 +CC(C)(C)Oc1cc(CNC(=O)C2CCCOC2)ccn1 +Cc1ccsc1C(=O)N1CCC(C(N)=O)c2ccccc21 +COc1ccc(-n2nc(CSc3nnnn3C)cc2O)cc1 +Cc1ccc(CNC(=O)NC2CCN(C(=O)c3ccoc3)CC2)s1 +CNCC(=O)OCc1ccc2c(c1)C(C)(C)C(=O)N2C +COCc1cc(C(=O)NC(C)(C)c2ccc3c(c2)OCO3)ccc1F +CCn1cc(CCC(=O)Nc2ccn(CC#N)n2)c(C)n1 +CC(C)CNC(=O)CC1NC(=O)c2ccccc2N=C1O +CN(C)c1cc(C(=O)NCc2ccccn2)ccn1 +CCCNC(=O)Cc1c(C)nc(SCc2ccccc2)[nH]c1=O +CCc1ccc(Cl)c(CC)c1NC(=O)CCC(=O)OC +CN(C(=O)Cc1csc(-c2cccnc2)n1)c1ccc(F)c(F)c1 +CCNC(=O)N1CCN(C(=O)c2n[nH]c(N)n2)CC1 +CC(C)c1cc(C(=O)N(CCC(N)=O)c2ccccc2)n[nH]1 +CNC(=O)c1cccc(NC(=O)c2ccc(C)c(Br)c2)c1 +O=C(NCCN1CCOCC1)c1ccc(-n2cccn2)nn1 +N#Cc1ccc(NCc2cccc(CN3CCCC3=O)c2)c(F)c1 +CN(Cc1ccc(-n2cccn2)cc1)C(=O)CCC(=O)c1ccccc1 +Cc1ccc(-c2noc(-c3c[nH]c(=O)cn3)n2)nn1 +CNC(=O)c1ccc(CNS(=O)(=O)N2CCCCCC2)cc1 +CCCOc1ccc(C(N)C(F)(F)F)cc1OCC +Cc1noc(C)c1CNC(=O)Nc1cnn(-c2ccccc2Cl)c1 +Cc1cc2n(n1)CCC(=O)N2CCCC(=O)NCc1ccco1 +O=C(Nc1cc(-c2cccs2)n[nH]1)c1ccc2nccnc2c1 +N#Cc1c(N)nc2c(c1-c1cnc(C3CCCCC3)nc1)COCC2 +C=CCN(Cc1cccs1)S(=O)(=O)c1cccc(C(N)=O)c1 +Cc1nc(-c2c[nH]c(C(=O)Nc3ccccc3OC(F)F)c2)cs1 +O=C(NCC(O)c1ccccc1C(F)(F)F)c1ccncc1 +Cn1ccsc1=NC(=O)CCC(=O)c1ccc(F)cc1 +CCCNC(=O)CN1C(=O)CNc2cc(C)c(C)cc21 +O=C1CCCCCN1CCNc1ncnc2[nH]cnc12 +O=C(c1ccccc1)C(O)n1nnc2ccccc21 +COc1ccccc1OCC(=O)N1CCCC1c1ccc[nH]1 +O=C(NCCc1cccnc1)NCc1cc(=O)[nH]c2ccccc12 +Cc1cccc(C)c1OCc1c(C#N)nnn1C(C)C +CCc1nc(C)ncc1C(=O)N1CC(C)C(N2CCOCC2)C1 +COc1ccc(F)cc1NC(=O)c1cnn(-c2ccccn2)c1C +Cc1cc(C)c(S(N)(=O)=O)cc1C(=O)Nc1nccs1 +Cc1cc(C(F)F)n2nc(C(=O)Nc3ccc(F)c(F)c3)nc2n1 +Cc1cc(C(O)COc2ccccc2)cc2c1NC(=O)C2C +O=C(NCC1CN2CCCCC2CO1)N1CCCC1C1CCCC1 +COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)CC1CCCC1 +O=S(=O)(Nc1cccc(O)c1)c1ccc(F)cc1F +CCCNS(=O)(=O)c1ccc(-c2c(C)noc2C)cc1 +CSc1nc(-c2cccnc2)nc(-c2ccccc2)c1C#N +COCCCNC(=O)Cn1ncn2c(cc3sccc32)c1=O +COc1ccccc1C(=O)Nc1cccc(S(N)(=O)=O)c1 +CCOC(=O)c1noc2ncnc(Nc3ccc(OC)cc3)c12 +CCc1cccc(C)c1NCC(=O)Nc1cc(OC)ccc1OC +COc1ccc2nc(NC(=O)c3cccc4cn[nH]c34)sc2c1 +CCN(C(=O)CCc1ccccc1F)C(C)CO +CCNS(=O)(=O)c1ccc(OC)c(C(=O)N2CCOCC2)c1 +Cc1cccnc1C(C)NC(=O)CCCc1cn[nH]c1 +O=C(NC(Cc1ccccc1)C1CC1)C1CCCO1 +CCCC(=O)Nn1cnc2c(cnn2C(C)(C)C)c1=O +CN(Cc1cccnc1)S(=O)(=O)c1ccc2c(c1)CCO2 +O=C(NCCNC(=O)C1CC1)c1cc(Cl)cc(Cl)c1 +COc1cc2c(cc1OC)CN(C(=O)C(C)Oc1ccccc1)CC2 +COC(=O)c1ccc(CSc2nnc3n2CCCCC3)cc1F +CC(C)Oc1ccc(NC(=O)NCCc2ccccn2)c(F)c1 +CC(=O)N1CC(C(=O)Nc2cc(C)ccn2)Oc2ccccc21 +Cc1cc(C(=O)Nc2cccn(C)c2=O)c(C)n1Cc1cccs1 +CCC(=O)c1ccc2c(c1)N(CC(=O)NC1CCCC1)C(=O)CO2 +CN1CCC(C(=O)Nc2ccnc(Sc3ccccn3)c2)CC1=O +CN(C)C(=O)c1nc(CN2CCOC(c3ccc(F)cc3)C2)no1 +Cc1ccc(NC(=O)c2cc(C3CC3)nc3ccccc23)nc1 +O=C(c1scnc1C1CC1)N1CCOc2ccc(Cl)cc21 +CCCC(=O)N1CCN(c2cc(C)c(C(C)=O)cc2F)CC1 +COc1cc(C2NCCc3cccc(OC)c32)ccn1 +CNC(=O)c1cccc(OC(=O)C2CCN(c3cnccn3)CC2)c1 +CC(C)(C)c1csc(SCC(=O)Nc2ccccn2)n1 +O=C(CNc1c(F)cccc1F)N(Cc1ccccc1)C1CC1 +CC(=O)Oc1ccc2c(c1)c(C(C)=O)c(C)n2-c1ccccc1 +COc1cccc(CCC(=O)Nc2cccc(C)n2)c1OC +COC(=O)C1CCN(S(=O)(=O)NCCO)CC1 +CC(C)CC(NC(N)=O)C(=O)Nc1ccc(OC(F)F)c(Cl)c1 +CCOc1cccc(NC(=O)N(C)Cc2ccccc2)c1 +Cc1ccc(NC(=O)NCc2ccccc2)cc1N1CCCC1=O +COCCOc1cccc(CNc2ccccc2)c1 +CCCn1c(C2CCN(Cc3cccs3)C2)nc2cccnc21 +Cc1nc(-c2ncccn2)[nH]c(=O)c1CC(=O)NC1CCCC(C)C1 +COC(=O)c1ccc(Oc2cc(C)nc(N)n2)cc1 +COc1ccc(C(=O)CCC(=O)N2CCC(O)C2)cc1F +OCCc1nnc(CCc2ccc3c(c2)OCO3)o1 +O=C1CCCCCN1Cc1cncn1Cc1ccccc1 +CN(C)C(=O)CCNC(=O)Nc1cccc(Cl)c1Cl +Cc1nn(C)c2ncc(C(=O)Nc3cc(C(C)(C)C)ccc3O)cc12 +CC(=O)c1cc(Br)ccc1OCC(=O)N(C)C1CC1 +Cc1ccnn1-c1cccc(NC(=O)NCCN2CCOCC2)c1 +NC(=O)c1cccc(S(=O)(=O)Oc2ccccc2)c1 +Cc1cccc2c1C(C1=CC(O)C(O)C(O)C1)NCC2 +CC(O)NC(=O)C1CC(=O)N(c2ccc(O)cc2)C1 +COC(=O)CCC(=O)N(C)Cc1c(F)cccc1Cl +CCCNC(=O)c1cc2sccc2n1C(C)C +Cc1cc(-c2cc(=O)n(CC(=O)NC(C)C)nc2C(C)C)on1 +CCCCC(=O)NCC1(N2CCOCC2)CCCCC1 +Nc1cn(Cc2ccc(S(N)(=O)=O)cc2)cn1 +O=c1[nH]c2cc(C(F)(F)F)cc(Br)c2[nH]1 +CC(Cc1ccccn1)N(C)C(=O)Cc1ccc(F)c(F)c1F +CC(=O)c1c(C)nc(C)nc1SCc1ccc(C(N)=O)cc1 +Cc1ccc(-n2c(-c3ccn[nH]3)n[nH]c2=O)cc1C +CCn1nc2c(cc1=O)CN(Cc1nnnn1-c1ccccc1)CC2 +c1cncc(-c2nnc(-c3cnc4onc(C5CC5)c4c3)o2)c1 +Cn1cc(-c2nn(Cc3ccccc3)c3c2CNCC3)nn1 +CC(C)C(OCC1CCCO1)C(=O)N1CCc2ccc(O)cc2C1 +Cn1ncc2c(-c3nc4ccc(N)cc4[nH]3)cccc21 +Cc1cc(C)n2nc(C(=O)NCCc3cccs3)nc2n1 +O=C(c1cnc(C2CCCO2)s1)N(Cc1cccc(F)c1)C1CC1 +Cc1cncc(C2CCCN(Cc3nccs3)C2)n1 +N#Cc1cn(C2CC2)c(=O)n(CCCc2nc3ccccc3o2)c1=O +CC(C)n1cc(NC(=O)N2CCOCC2C2CC2)cn1 +COc1cc(CC(=O)Nc2cc(C)nn2C)ccc1C +C#CCC(NC(=O)c1ccc(-n2ccnn2)cc1)C(N)=O +COc1cccc(C(=O)CNC(=O)OC(C)(C)C)c1 +CC1CN(C(=O)COC(=O)Cc2c(F)cccc2Cl)CC(C)O1 +CCOC(C)c1noc(CN2CC(C)OCC2C)n1 +COc1ccc(C(C)NC(=O)c2csnn2)cc1Br +CCN(Cc1c(F)cccc1F)C(=O)CCCc1nc(C)no1 +O=C(NCCc1ccc(OC(F)F)cc1)NCc1ccco1 +CCCCN1C(=O)C(C)Sc2ccc(C(C)=O)cc21 +Cc1cc(C)nc(Nc2nc(C(=O)Nc3ncc(C)s3)cs2)n1 +CCOCCCNC(=O)Nc1ccccc1S(C)(=O)=O +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(F)cc2[nH]cnc12 +O=C(CCN1CCOCC1)Nc1ccc(OC(F)(F)Cl)cc1 +Cc1csc(-c2c[nH]nc2-c2c(C)cc(O)cc2O)n1 +Cc1ccc(C(=O)N(CC(=O)N(C)C)CC(F)(F)F)cn1 +CSc1ccc(CNC(=O)C2COCCO2)cc1 +CN(C)C(=O)N1CCN(C(=O)c2cccs2)CC1 +Cc1ccccc1NC(C)C(=O)Nc1cccc(S(N)(=O)=O)c1 +CCCn1cc(NC(=O)c2cnns2)ccc1=O +COc1ccc(C(=O)N(C)C)cc1NC(=O)COCC(F)(F)F +c1ccc(-c2nc3c(c(N4CCOCC4)n2)CNCC3)nc1 +COc1ccnc(Oc2ccc(C#N)cc2Cl)n1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1cc(C(C)(C)C)nn1C +O=C(CSc1nnnn1-c1ccccc1)Nc1ccc(O)cc1 +O=C(Cc1ccc(F)cc1)N1CCCCC1c1nncn1CC1CC1 +CCS(=O)(=O)c1ccc(NC(=O)NCc2ccccc2)cc1 +C=CCCCNc1cc(Cl)ccc1NC(C)=O +O=C(Cc1ccccc1)NCC(=O)Nc1cccc2ncccc12 +CC1CCCN(C(=O)CSc2nnc3n2CCCCC3)C1 +CN(C)C(=O)CCc1ccc(OCc2ccccc2)c(N)c1 +CCCn1nc(C)c(CN(C)Cc2nc(-c3cccnc3)no2)c1C +COc1cccc(NC(=O)COC(=O)c2ccc3c(c2)CCC3)c1 +C#CCN1C(=O)C(Cc2ccc(OC)c(N)c2)Oc2ccccc21 +CCOc1ccc(NC(C)=O)cc1S(N)(=O)=O +O=C(COC(=O)c1cncn1-c1ccccc1)c1ccc[nH]1 +CN(CCOCC1CC1)C(=O)c1cc2c(nc3sccn32)s1 +Cc1occc1-c1nnc(SCCOc2ccccc2F)o1 +Cc1c(C(N)=O)nnn1Cc1ccc(Br)cc1 +COc1cc(C(=O)NC(C)CC(O)c2ccco2)ccc1F +Cc1cc(F)ccc1S(=O)(=O)Nc1ccc(C(=O)N(C)C)cc1 +COCc1ccc(CNC(=O)NC(C)COC)cc1 +COCC#CCN1CCN(c2ccccc2C#N)CC1 +CCN(CC)C(=O)CCC(=O)Nc1ccnn1-c1cccc(Cl)c1 +CC(C)(CNC(=O)c1cc2c(F)cccc2[nH]1)c1ccncc1 +Nc1ncc(C(=O)Nc2ccc(Cl)cn2)cc1Cl +O=c1nc(Nc2ncccn2)sc2ccccc12 +Fc1cc(CSc2nnnn2CC(F)(F)F)c2ncccc2c1 +Cc1nc(-c2cccc(NC(=O)c3cn(C)nc3C(C)(C)C)c2)no1 +CCn1c(SC(C)C(=O)N2CCCCC2)nc2ccccc21 +COc1ccnc(N2CCN(c3nnnn3-c3ccccc3)CC2)n1 +Cc1ccc(-n2nnc(C(=O)N3CCOCC3)n2)cc1 +Cc1[nH]c2ccccc2c1C1=CCN(C(=O)Nc2ccccn2)CC1 +CSc1nnc(SC(C)C(=O)Nc2cccc(C#N)c2)s1 +NC(=O)C1CCN(C(=O)NCCOCc2ccccc2Cl)C1 +CCOC(=O)c1cnn2c(C(=O)OC)cc(-c3ccc(F)cc3)nc12 +COc1ccc(NC(=O)CN(C)C(=O)c2cc3c(s2)CCC3)cc1 +Cc1nc(Cn2cc(Cl)cn2)n(-c2cccc3cccnc23)n1 +CCOc1ccccc1C(=O)N1CCN(CCC(=O)NC(C)C)CC1 +COC(=O)CNC(=O)NCc1cccc(C(F)(F)F)c1 +O=C(NCC(F)(F)F)c1cc(Cl)ccc1O +O=C(Cc1ccsc1)N1CCCN(c2ccc(F)cc2)CC1 +O=c1c(O)c(-c2cccc(O)c2)oc2cc(O)ccc12 +CC(=O)c1cc2ccc3c(c2oc1=O)CN(C1CCCCC1)CO3 +CC(=O)NC(C)C(=O)NC1CCCCC1OCCC(C)C +COc1cc(N2CCN(C(=O)c3ccccc3F)CC2)nc(C)n1 +O=C(CNC(=O)c1ccco1)Nn1cnc2ccccc2c1=O +Cc1nc(CNC(=O)Nc2c(C)cc(Cl)cc2C)c(C)s1 +Cc1nn(CCC(=O)N2CCOCC2)c(C)c1Cl +COc1ccc2cc(CNc3ccc(C)cc3)c(=O)[nH]c2c1 +COc1cccc(-c2nnn(Cc3nnc(C(C)(C)C)o3)n2)c1 +Cc1ccc(SCCC(=O)Oc2cccc(C(N)=O)c2)cc1 +CC(C)=CCC1(CO)CCCN(c2nc(C(N)=O)cs2)C1 +CCOC(=O)c1ccc(NC(=O)CSc2nnnn2C)cc1 +COC(=O)c1c(C)[nH]c(C(=O)OCC(=O)c2ccc(F)cc2)c1C +Cc1cn[nH]c1C1CCCN(S(=O)(=O)c2ccc(Cl)cc2)C1 +C#CCN1CCN(CC(=O)NCCCc2ccccc2)CC1 +CC(C)c1ccc(C(C)NC(=O)c2ccn(C)c(=O)c2)cc1 +N#Cc1ccccc1Cn1c(C#N)nc2cc(N)ccc21 +Fc1cc2c(c(F)c1Cl)CCNC2Cn1cnnn1 +O=C(OCCC(F)(F)F)c1cnn(-c2ccc(F)cc2)n1 +CC(=O)Nc1ccc(C(=O)NCc2cccc(Br)c2)cc1 +CN(C)C(=O)N1CCN(C(=O)NCCc2cccc(Cl)c2)CC1 +CC(C)(C)OC(=O)NCCCNC(=O)C1(C)CC1(Cl)Cl +CN(C)C(=O)CCCC(=O)NCc1ccc(F)cc1 +COc1cccc2ccc(-c3nn4c(-c5ccco5)nnc4s3)nc12 +COc1cccc(C(=O)NC(c2cccnc2)c2cccc(OC)c2)c1 +COCc1cc(=O)n(CC(=O)Nc2ccc3c(c2)OCCO3)c(N)n1 +CC(C)CNc1nnc(SCC(=O)NC2CC2)s1 +CCCCn1nc(C(=O)Nc2ccc(Cl)cc2C)ccc1=O +CCc1ccccc1OCC(=O)Nc1ccc(OC)c(OC)c1 +Cn1c(=O)c2cc3cc(F)ccc3nc2n(C)c1=O +Cc1noc(C2CCN(C(=O)c3sc(C(C)C)nc3C)CC2)n1 +O=C(CN1CCOc2ccc(F)cc21)Nc1cccc(F)c1 +COc1ccccc1-c1cnc(CNCCc2ccccn2)s1 +CCOC(=O)c1sc2nc(C)nc(SCC#N)c2c1C +Cc1cccc(C(=O)N2CCc3c(c(-c4nc(C)no4)nn3C)C2)c1 +COC1CCCN(C(=O)C(Cc2cccc(F)c2)n2nnnc2C)C1 +Cc1cccn2cc(C(=O)NCCCN3CCOCC3)nc12 +COC(=O)C(C)NC(=O)Cn1cccc(C(F)(F)F)c1=O +O=C(OCCN1CCCC1=O)c1ccc(Cl)cc1Cl +CC(C)(CO)NC(=O)Nc1ccc(N2CCCC2=O)cc1 +COc1cccc(CNC(=O)c2cc(=O)oc3cc(OC)ccc23)c1 +Cn1cccc1C1COCCN1C(=O)CCc1cccs1 +C=CCOC(=O)c1cc(S(=O)(=O)N2CCCC2)cn1C +Cc1cc(N(C)Cc2csc(C)n2)n2nc(C)c(C)c2n1 +COC(=O)CCNC(=O)c1cccc(OC)c1F +COC(=O)CNC(=O)Nc1ncc(-c2ccc(OC)cc2)n1C +CCn1c(=O)c2c(nc(N)n2CC)n(CC(C)C)c1=O +O=C(Nc1onc2c1CCCC2)c1nc(-c2cnccn2)no1 +CCOC(=O)c1ccc(N2C(=O)CC(=O)N=C2O)cc1 +CN(C)C(=O)CCN1CC(C)(Cc2ccc3c(c2)OCO3)CCC1=O +Cc1cc(C)c(CNC(=O)c2cccnc2)c(=O)[nH]1 +COCc1nc(C2CCCCCN2C(=O)c2ccccc2)no1 +COCCn1c(C)cc(-c2ccc(OC)c(C)c2)c(C#N)c1=O +O=c1c2ccccc2ncn1Cc1nc2ccccc2n1C(F)F +O=C(c1c(F)cccc1Cl)N1CCN(CC2=CCCOC2)CC1 +CN(C)C(=O)c1cc(NC(=O)c2cn(C)nc2C(C)(C)C)ccc1F +COCC(C)NC(=O)NCc1ccc(NC(=O)NC(C)C)cc1 +O=C(Cn1nc2n(c1=O)CCCCC2)Nc1ccc2c(c1)CC(=O)N2 +CS(=O)(=O)c1ccc(O)c(Br)c1 +CCn1ccc(C(=O)Nc2c(C(=O)OC)sc3ccccc23)n1 +COc1ccc(N2CC(C(=O)Nc3c[nH]ccc3=O)CC2=O)cc1 +COc1cc(CCC(=O)N(C)c2cccc(C#N)c2)cc(OC)c1 +O=S(=O)(c1sccc1Br)N1CCCCC1CO +CC1CN(C(=O)C2CCN(c3ccccc3)CC2)CC(C)O1 +CSc1ccc(CNc2ccc(CC(=O)N(C)C)cc2)cc1 +Cn1ncc2c(NCc3noc(C(N)=O)n3)nc(C(C)(C)C)nc21 +CCCCS(=O)(=O)N1CC2CCC3(N=C(CC)N(C)C3=O)C2C1 +COc1ccc(C(=O)NCCC(=O)NC2CCCC2)cc1F +COc1cc(Cl)c(-c2nnc(CCO)o2)cc1Cl +Nc1nc(NC2CCCCC2)nc(C(F)(F)F)n1 +O=C(NCCc1cn2ccccc2n1)Nc1ccccc1N1CCCC1 +Nc1nc(N2CCOCC2)ncc1C(=O)NC1CCCC1 +COc1ccc(C(C)=O)cc1NC(=O)C1CCCO1 +COC(=O)c1cccc(CSc2nc(C)c(CCO)c(=O)[nH]2)c1 +CCCOCc1ccccc1CNC(=O)c1cccc(C#N)c1 +CN(c1ncccn1)C1COC2(CCN(C(=O)c3ccncc3)C2)C1 +O=C(NCC1CCN(S(=O)(=O)c2ccccc2)CC1)c1ccc[nH]1 +CCOCCS(=O)(=O)Nc1ccc(NC)cc1 +O=C(c1ccccc1Cl)N1CCN(c2ccccc2)CC1 +CC(C)OCCC(=O)NC(C)c1cccc(O)c1 +CNC(=O)c1cc(S(=O)(=O)Nc2ccc(C)c(C)c2)ccc1OC +Cc1cc(C(=O)NCCC(C)C)c2nc3n(c2n1)CCCCC3 +Cc1ccc(C(=O)N2CCN(c3cc(N(C)C)nc(C)n3)CC2)cc1 +O=c1oc(-c2cccs2)nn1Cc1ncc(-c2ccc(F)cc2)o1 +Cc1ccc(C(=O)N2CCCC2C(=O)NCc2ccco2)cc1 +CC(C)C(C)NC(=O)c1cncc(C(=O)NC(C)C(C)C)c1 +CCn1ncc(C(C)NC(=O)C2CCN(S(C)(=O)=O)CC2)c1C +Cc1csc(N2CCCN(C(=O)c3ccoc3C)CC2)n1 +CN(Cc1ccc(F)cc1)C(=O)c1ccccc1S(C)(=O)=O +CNS(=O)(=O)c1ccc(S(=O)(=O)NCc2cccs2)cc1 +COc1ccnc(N2CCN(CC(=O)Nc3c(C)n[nH]c3C)CC2)n1 +Fc1ccccc1CNc1ncnc2c1cnn2-c1ccccc1 +Cc1c(C(=O)NC2(C#N)CC2)nnn1-c1ccc(-c2ccccc2)cc1 +CCCCn1nc(C(=O)Nc2ccc(C(N)=O)cc2)ccc1=O +C#CCCN1CCN(C(=O)CNC(=O)c2ccc(OCC)cc2)CC1 +CSc1nnc(SCCC(=O)OC(C)(C)C)s1 +Cc1nc(-c2ccc(NC(=O)c3cc(C(N)=O)cs3)cc2)cs1 +Cc1cc(N2CCCC(c3ccn[nH]3)C2)nc(N)n1 +COC(=O)N1CCC(NC(=O)Nc2ccc(Cl)c(Cl)c2)CC1 +CC1CCCC(C#N)(NC(=O)CNC(=O)c2cc3ccccc3[nH]2)C1 +CC(C)CNC(=O)Nc1ccc(NC(=O)C2CCCO2)cc1 +CC1CCCC(N2C(=O)c3ccccc3S2(=O)=O)C1C +Cc1occc1C(=O)Nc1cccc(-n2cnnc2)c1 +CCC(=O)Nc1cc(N2CCN(c3ccccc3)CC2)ncn1 +COc1ccc(C)cc1-n1nnnc1SCC(=O)N1CCCCC1 +FC(F)CN(Cc1ccccc1)Cc1cccnc1 +CCC(=O)NCC(=O)Nc1ccc(-c2nc3ccccc3[nH]2)cc1 +COc1ccc(C(=O)NC(O)C(=O)c2ccccc2)cc1 +Cn1cc(C(O)CNC(=O)c2ccc(F)cc2F)c2ccccc21 +CC1(C)Cc2ccc(N)cc2N(CCCC#N)C1=O +CCn1ccc(=O)nc1SCc1ccn(-c2ccccc2)n1 +CCN(CCO)C(=O)c1c(C)nc(C(C)C)[nH]c1=O +CCN(CC)C(=O)c1c(C)nc(N)nc1COc1cc(C)ccc1C +Cc1nnc(SCCOc2ccc(Cl)cc2Cl)n(N)c1=O +CCOc1cccc2sc(=NC(=O)c3ccn(C)n3)n(C)c12 +COc1ccc(CCNC(=O)N2CCN(C(=O)N(C)C)CC2)cc1 +COc1ccc(CNC(=O)c2cccnc2-n2cncn2)cc1 +CCN(CC)C(=O)c1cccc(S(=O)(=O)NCC2CCCO2)c1 +CCc1oc(-c2ccc3c(c2)OCO3)cc1CC#N +N#Cc1ncn(CCn2nc3ccccn3c2=O)n1 +COc1ccccc1OC(=O)Cc1ccc(-n2cnnn2)cc1 +Cc1cc(C)cc(NC(=O)C2CC(=O)N(Cc3ccccn3)C2)c1 +NC(=O)NCc1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1 +Cc1sc2ncn(N)c(=O)c2c1-c1ccc(Cl)cc1 +C#CCOc1ccccc1CNc1ccc(NC(C)=O)c(OC)c1 +CC(OC(=O)CC1CCCO1)c1c(F)cccc1N1CCOCC1 +O=C(NC1CCN(c2ccccc2F)C1=O)c1ccc2[nH]cnc2c1 +CCC(=O)C1CCCCN1S(=O)(=O)c1cccc(F)c1 +CCc1ncc(C(=O)N2CCC(OCc3ccccc3F)CC2)s1 +Fc1ccc(-c2nc(C3CC3)no2)cc1Br +Cn1cc(C(=O)Nc2ccccc2NCCc2ccccn2)cn1 +COc1ccccc1CNC(=O)c1cnc(N2CCCCC2)nc1C +CCCCn1ncnc1Cc1ccc2nc(C)[nH]c2c1 +Nc1c(NCc2ccco2)ncnc1Nc1cccc2ncccc12 +Cc1occc1-c1nnc(SC2CCN(C)C2=O)n1N +CC(C)Oc1ccccc1C(=O)Nc1ccccc1C(N)=O +CC(C)(O)CCc1ccc(C(=O)NCC(O)c2ccccc2F)cc1 +O=C(NCc1cccnc1)C1CC(=O)N(CC(F)(F)F)C1 +O=C(Nc1ccc2cc[nH]c2c1)c1ccc2nc(C(F)(F)F)[nH]c2c1 +O=C1CCCCN1CC(=O)N1CCOC(CCCc2ccccc2)C1 +O=C(Nc1ccc(-n2ccnn2)cc1)c1ccc(OCC(F)F)nc1 +CCC(C)NC(=O)c1cccc(S(=O)(=O)NCc2ccco2)c1 +Cc1nccc(C2CC3CCN(C(=O)CC4=CCCCC4)CC3O2)n1 +CC(C)Oc1ncccc1CNC(=O)N1CCOCC1 +Cc1ccc(-n2ccnc2)c(C(=O)Nc2ccncc2)c1 +COCc1nc(NCCc2ccccc2)cc(OC)n1 +Cc1nc(CCC(=O)NC(C(N)=O)C(C)(C)C)oc1-c1ccccc1 +N#CC(C(=O)c1ccsc1)c1ccc(F)cc1Cl +CCOC(=O)CCC(=O)Nc1cccc(C(=O)N2CCCCCC2)c1 +CN(Cc1c[nH]nc1-c1cccnc1)C1CCc2ccccc2C1 +CCn1c(SCCN2CCOCC2)nc2sc(C)cc2c1=O +N#Cc1c(-c2cccc(C(F)(F)F)c2)nn(-c2cnccn2)c1N +CCOc1ccc(NC(=O)NCCCC(N)=O)cc1 +O=C1CCC(C(=O)NCc2ccc(Br)cc2)N1 +COc1ccc(F)c(NC(=O)C2CCN(C(=O)c3ccoc3)CC2)c1 +CNS(=O)(=O)c1ccc(-n2cccn2)c(N)c1 +Oc1cccc(-c2cc(O)cc(Br)c2)c1 +CC1CCCC(N(C)C(=O)c2ccc(NC(=O)NC(C)C)cc2)C1 +Cc1c(C(=O)N2CCOC(C)C2)cnn1-c1ccccc1 +O=S(=O)(Cc1ccccc1F)NCc1ccccc1 +CCCn1c(=O)[nH]c(=O)c2c1nc(NCC)n2CC +COCc1cccc(NC(=O)NC2COc3c(cccc3OC)C2)c1 +CCOc1cc(C=c2sc3ncnn3c2=O)ccc1OC(C)=O +COc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cc1F +CCc1noc(CC)c1CNC(=O)c1ccc(-n2ccnc2)nc1 +FC(F)(F)c1cccc(CNc2nc(C3CC3)no2)c1 +COC(=O)CC1CCCCN1C(=O)CCCc1ccccc1 +CCc1cc(C(=O)NC2(CO)CCCC2)sc1C +CC(Cc1ccsc1)NC(=O)C(C)NS(C)(=O)=O +O=C(Nc1cccc(C(F)(F)F)n1)c1scnc1C1CC1 +Cc1ccc(-n2[nH]c(C(=O)Nc3ccnc4ccnn34)cc2=O)cc1 +Cc1ccc(N2CCN(C(=O)c3ccccc3F)CC2)cc1N +COCCNC1C(=O)Nc2cc(Br)ccc21 +O=C(Nc1cc(F)c(F)cc1F)c1cccc(C(=O)N2CCCC2)n1 +COCCNc1nc2c(ccc3ccccc32)s1 +O=C(NCC(O)c1ccc2c(c1)OCO2)c1ccco1 +OCCN(Cc1cnc(C2CCCC2)s1)C1CCc2ccccc21 +O=C(Nc1cn[nH]c1)C1Cc2cc(Cl)ccc2O1 +CCOc1cccc(CC(=O)Nc2cccc(-c3cn[nH]c3)c2)c1 +CCCCn1nc(C(=O)NCCc2ccccc2C)ccc1=O +Cn1ccc2c(C(=O)Nc3ccnc4ccnn34)cccc21 +COc1ccc(-c2noc(Cn3ccc(C)c(C#N)c3=O)n2)cc1 +O=C(COc1ccccc1)N1CCC(Oc2cccnc2)CC1 +CCn1nccc1C(=O)N1CCC(Nc2cccn3ncnc23)CC1 +O=C(c1ccccc1)N1CCC(c2nccnc2-n2ccnc2)CC1 +COc1ccc(-c2csc3nc(C)[nH]c(=O)c23)cc1 +Cc1cc2cc(C(=O)N3CCCC3c3ccco3)ccc2o1 +Cc1ccoc1C(=O)Nc1ccc(SC(F)F)cc1 +CCOC(=O)c1ccc(NC(=O)c2cnn(-c3ccccc3)n2)cc1 +CCC(=O)N1CCC2(CC1)CC(CC(=O)NC(C)C)c1ccccc12 +COc1cc(OC)cc(C(=O)NCC(=O)Nc2nnc(C)s2)c1 +CCN(C(=O)CNc1cccc(Cl)c1F)C1CC1 +N#Cc1c(SCC(N)=O)nc2c(c1-c1ccncc1)CCCC2 +CCC(CC)CN(CCC#N)C(=O)C1CC2CCC1O2 +CCOc1ncccc1C(=O)Nc1ccc2c(c1)OCO2 +CC(CO)NC(=O)Cn1c2ccccc2c(=O)c2ccccc21 +O=C(Nc1cccc(F)c1F)c1ccnc(F)c1 +Cc1cc2ccccc2n1CCCNC(=O)c1ccc(=O)oc1 +Cc1cccc(CCC(=O)N(Cc2ccco2)CC2CCCO2)c1 +O=C(COc1cccnc1)N1CCN(Cc2cccc(F)c2)CC1 +CCCCNC(=O)CCC(=O)c1cc(C)ccc1C +Cc1ccc(C)c(S(=O)(=O)NCCNC(=O)C2CCC(=O)N2)c1 +CC(=O)c1cc(C(=O)NC2CCCCC2C)n(C)c1 +CCOC(=O)c1nnc(-c2c(-c3ccc(F)cc3)noc2C)o1 +Cc1cc(C(=O)NCc2nnc3ccc(C(F)(F)F)cn23)c(C)o1 +COC(=O)c1ccnc(NC(=O)Cc2cccc(F)c2F)c1 +CCNC(=O)N(C)Cc1ccc2c(c1)OCCO2 +Nn1c(SCC(=O)NCc2ccco2)nnc1-c1cccnc1 +O=C(NCC#Cc1ccccc1)c1nc2ccccc2c(=O)[nH]1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CCCO3)CC2)cc1 +Cc1occc1-c1nnc(SCC(=O)NCC(C)C)n1N +Cc1ccc(-n2ccnc(NCc3ccccc3)c2=O)cc1F +CC(C)Cc1nc(C(=O)C(C#N)c2ccccn2)cs1 +CCc1cc(C(=O)NC(C)Cn2ccnc2)sc1C +CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ncccc2C#N)C1 +CN(C(=O)CSc1nc(-c2ccccc2F)n[nH]1)C1CC1 +CN1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 +Cc1noc(C)c1C1CCCN1C(=O)c1ccc2ccn(C)c2c1 +Cc1ncccc1OCC(=O)N(C)c1ccccc1 +CCCCc1nc(CN2CCCC2c2noc(C)n2)no1 +Nc1nnc(SCc2csc(-c3ccoc3)n2)n1C1CC1 +COc1cccc(CNC(=O)c2nnn(-c3ccc(F)cc3)c2N)c1 +CCC1CCC(NC(=O)c2scnc2C2CC2)CC1 +O=C(c1nn2cccnc2c1Cl)N1CCc2ncc(Cl)cc2C1 +COCCN1CCCC(O)(CN2CCc3ccccc3C2)C1=O +CC(C)C(=O)Nc1cccc(NC(=O)NCc2ccnn2C)c1 +CCNS(=O)(=O)c1cccc(C(=O)Nc2ccc(C)cc2C)c1 +CC(=O)c1csc(NC(=O)CCSc2ccccc2)n1 +Cc1nc(CCn2ccccc2=O)n(-c2ccc(F)cc2F)n1 +O=C(NCC#Cc1ccccc1)NCC1CCCOC1 +CCOc1ncccc1C(=O)OC1CCCC(C)C1 +COc1ccc(S(=O)(=O)Nc2cccc(Cl)c2)cc1OC +COCc1ccc(C(=O)Nc2cccc(OCC(F)(F)F)c2)o1 +O=C(c1cnc(C2CCCO2)s1)N1CCCC1Cc1ccccc1 +O=C(COC(=O)C1CC2CCCC(C1)C2=O)NCc1ccco1 +COc1cccc(C2CC(=O)Nc3c2c(C)nn3C)c1 +Nc1cccc(Oc2ccnc(C(F)(F)F)n2)c1 +COc1cc(C(=O)Nc2ccccc2C(N)=O)ccc1OC(C)C +CCCN(C)C(=O)NCc1ccnc(OC(C)(C)C)c1 +CCOC(=O)c1c(C)c(C)n(Cc2cccc(OC)c2OC)c1C +CCC(Oc1ccccc1)C(=O)NCC1CCCO1 +CC(CC#N)N(C)C(=O)Nc1ccc2c(c1)Cc1ccccc1-2 +Cc1n[nH]c(C)c1S(=O)(=O)NCc1ccncc1 +CC(C)n1cnnc1CN(C)Cc1cnc(-c2cccs2)nc1 +CCC1Oc2cc(N)ccc2N(CCCO)C1=O +CSc1cc(C(=O)NCCc2cccnc2)ccn1 +CC(C)Oc1cc(N2CCN(C3CCCC3)C(=O)C2)nc(N)n1 +CC1CCCCC1OCC(=O)Nc1nccn(C)c1=O +Cn1c(C(C#N)C(=O)CCc2ccc(F)cc2)nc2ccccc21 +Cc1n[nH]cc1CNC(=O)c1ccc(OCC(C)C)cc1 +CCCC1CC1C(=O)N1CCc2nc(C)n(C)c(=O)c2CC1 +CCCN(Cc1ccc(C#N)cc1)C(=O)CNC(C)=O +Cc1cccc(CNC(=O)c2cccnc2OCC(F)F)c1 +CCOCCCNC(=O)c1cc(CC)c(C)s1 +COc1cccc(C(=O)NC(C)c2cccc(NS(C)(=O)=O)c2)c1 +Cc1cc2c(SCc3nsc(N(C)C)n3)ncnc2s1 +O=C(NCc1cscn1)Nc1nc(-c2ccccc2)ns1 +CCN1CCOC(CCNC(=O)Cc2cn(C)c3ccccc23)C1 +CC(O)CNC(=O)Cc1c(Cl)cccc1Cl +COc1cccc(NCCC(=O)c2ccccc2OC)c1 +Cc1cnc(C(C)CNC(=O)NCc2nc(C)c(C)s2)s1 +CC(C)CC(NC(=O)Nc1cccnc1)C(=O)Nc1cc[nH]n1 +CN(C)C(=O)Cc1ccc(NC(=O)NCc2ccccc2F)cc1 +CC(C)(CNC(=O)NCCNC(=O)c1ccco1)c1ccccc1F +N#CC(NC(=O)COC1CCCCC1)c1ccc(F)cc1F +CCc1cccc(NS(=O)(=O)c2ccc(-c3nnc(C)o3)o2)c1 +COc1ccccc1CCNc1cncc(-n2cccn2)n1 +COc1ccc(C(=O)NCc2cccc(C)c2)cc1OCCO +CC(=O)c1cccc(NC(=O)N2CC(C)CC(C)C2)c1 +CC(C)(C)C(=O)N1CCN(C(=O)c2ccccc2O)CC1 +CCCCN(C)C(=O)C1CCN(C(=O)Nc2ccnn2C(C)C)CC1 +Nc1nc(SCC(=O)Nc2nonc2-n2cccc2)n[nH]1 +O=C1COc2cc(-c3c(N4CCCCCC4)c(=O)c3=O)ccc2N1 +Cn1nccc1C(=O)Nc1ccc(Cl)cc1F +CCN(CCC(=O)OC)C(=O)c1ccc(C2CCCCC2)cc1 +Cn1ncc2c(=O)n(CC(=O)Oc3ccccc3Cl)cnc21 +Cc1cccc(NC(=O)CN(C)C(=O)CCc2c(C)nn(C)c2C)n1 +CCC(C)Oc1ccc(NC(=O)c2ccc(F)c(NC(C)=O)c2)cc1 +CCC(=O)N(C)C1Oc2ccc(O)cc2C1(C)c1cc(O)ccc1O +COc1ccc(C(=O)Nc2cc3c4c(c2)C(C)C(=O)N4CCC3)cc1 +Cc1ccc(CN2CCc3ccc(=O)n(CC(=O)N(C)C)c3CC2)o1 +Cc1ccoc1C(=O)N1CCC(=O)N(CC(C)C)CC1 +Cc1cccc(NC(=O)N2CCCC2C(=O)NCC(C)C)c1 +Cc1ccc(C)c(CC(=O)N2CCN(Cc3ccccc3)C(C#N)C2)c1 +COc1ccc(Cl)c(NC(=O)NC(C)c2cc(C)oc2C)c1 +Cc1nc(C)n(CC2CCCN(C(C(N)=O)c3ccc(F)cc3)C2)n1 +CN(CC1=Cc2ccccc2OC1)C(C(N)=O)c1cccc(F)c1 +O=C(NCCCCC1CCCO1)c1cn(C2CCCCC2)nn1 +Cc1ccccc1N(C)C(=O)c1c(C)oc2ncn(C)c(=O)c12 +Nc1cc(F)ccc1NC(=O)CCCN1CCOCC1 +CC(CCc1ccco1)N(C)C(=O)N1CCOCC1 +Cc1cccc(-c2nnc(CN3CCN(c4nccs4)CC3)o2)c1 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+CCSc1nnc(COc2cccc(C)c2)n1CC +CC(C#N)(NC(=O)COc1ccc(Cl)cc1Cl)C1CC1 +N#Cc1ccsc1NCc1cccc(F)c1Cl +CC(=O)Nc1ccc(CCNC(=O)NCCc2ccccn2)cc1 +CCCCNC(=O)C1CCC(C)N(C(=O)c2cc(C)ccc2C)C1 +COc1ccc(Cc2cc(-c3ccc(N)cc3)n[nH]2)cc1 +CCN(C(=O)Cc1csc(C)n1)c1ccccc1C(=O)OC +CN(CCC#N)C(=O)NC1CC(=O)N(c2cccc(F)c2)C1 +CC1CCN(C(=O)c2cccnc2)c2ccccc2S1 +CCN1C(=O)CCC(C(=O)NC)C1c1cnn(C)c1 +CN1c2ccccc2NCC12CCN(C(=O)OC(C)(C)C)CC2 +O=C(Nc1ccccc1)c1ccc(C(=O)Nc2ccccc2)nc1 +CCN(Cc1ccoc1)C(=O)c1ccc(OC)c(-n2cnnn2)c1 +COc1ccc(C2CCCCCN2C(=O)CNC(C)=O)cc1 +O=C(COc1cc(Cl)ccc1Cl)NCCO +CCCn1nc(C#N)cc1-c1ccc2c(c1)CCN2C(C)=O +COCCN1Cc2cccc(C(=O)Nc3ccc(F)cc3)c2C1=O +CCOC(=O)Nc1ccc(NCc2c(C)nn(C)c2C)cc1 +Cc1sc(-c2ccco2)nc1C(=O)NC1CCCCNC1=O +CC1(C)CN(C(=O)NCc2cc(Cl)c3c(c2)OCCO3)CCO1 +Nc1cc(C(=O)NCCc2c[nH]c3ccccc23)ccc1F +COc1ccc(C=CCS(=O)(=O)c2ccccc2)cc1 +COc1cc(C(=O)N2CCCC2)ccc1OCc1cscn1 +O=C(Cc1c[nH]c2ccccc12)Nc1cccc(N2CCCCC2=O)c1 +OC1C(O)C2OC3(CCCCC3)OC2C2OC3(CCCCC3)OC12 +CCc1nnc(-c2cccn2CC(=O)Nc2cccc(Cl)c2)o1 +Cc1nc2sc(C(=O)OCC(C)C)c(C)c2c(=O)[nH]1 +COc1ccc(C(N)c2nc(-c3ccccc3)cs2)cc1OC +COc1ccc(C(O)c2ccc(C)cc2)cc1OC +Cc1cc2cc(NS(=O)(=O)c3cc(F)ccc3F)ccc2[nH]1 +C=CCNC(=O)c1ccc(NC2CCCC2(C)CO)nc1 +O=C(CCN1CCOC(c2ccc(F)cc2)C1)NC1CCCC1 +CCN1CC(COC(=O)C2CC2c2ccccc2C)CC1=O +O=C(CCNc1ncccn1)N1CCN(Cc2ccncc2)CC1 +COc1c(Cl)c2c(c(OC)c1OC)CNCC2 +CS(=O)(=O)NC1CCN(C(=O)CCc2ccc(Cl)cc2)CC1 +NC(=O)Cc1cccc(OCc2nnc(-c3ccc(Cl)cc3)o2)c1 +Cc1cc(CNC(=O)N(C)CC2CCCC2)no1 +CNC(=O)c1ccc(NC(=O)NC2CC2c2cccc(Cl)c2)cc1 +CCc1c(C)nc(N)nc1N1CCC(C(C)N2CCOCC2)CC1 +COc1ccc(OC(C)C(=O)N2CCC(CO)C2)cc1 +Cc1nc(NCCNC(=O)Cc2ccccc2)cc(-n2cccn2)n1 +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2ccccc2C(N)=O)c1C +CCOC(=O)c1cc(C)sc1NC(=O)c1cc(C)nc2ncnn12 +Oc1ccc(F)c2c1CCNC2Cc1cccnc1 +CCn1ncc2c1CN(Cc1ccc(C)cc1)CC2COC +COc1ccnc(NC(=O)C(OC(C)(C)C)c2ccccc2)c1 +COc1ccc(C)cc1NC(=O)Cn1ncccc1=O +CN(C)C(=O)c1cccc(OC(=O)c2cccc(-n3cccc3)c2)c1 +CC1CCc2nc(NC(=O)c3ccc(-n4cncn4)cc3)sc2C1 +CC(C)(C)c1ccc2c(c1)C(=O)CC2CC(=O)NC1CC1 +NC(=O)c1ccccc1COc1ccc(N)c(Cl)c1 +COc1ccc(S(=O)(=O)NCC(OC)c2cccc(F)c2)cc1 +CCOC(=O)Cn1c(C)cc(=O)c2cc(OC)ccc21 +NC(=O)c1cnc(NCc2ccccc2Cn2cccn2)c(Cl)c1 +Cc1nc(CNC(=O)COc2ccc3c(c2)CCC3)c(C)s1 +O=C(c1ccc(Br)cc1F)N1CCOCC1 +CCCNC(=O)CCNC(=O)c1ccc(Cl)cc1 +COc1cc(NC(=O)c2cc(C(C)C)n3nccc3n2)cc(OC)c1 +O=C(c1cc(Cl)ccc1F)N1CCC(c2n[nH]c(C3CC3)n2)CC1 +Cc1cc(C(=O)n2ccnc2)c(C)n1CC1CCCO1 +CC(C)c1cccc(OCCC(=O)NCCO)c1 +Cn1cc(-c2nc(C3CCOC3)n[nH]2)c2ccccc21 +Cc1cc(NCCn2cccn2)n2nc(C(F)(F)F)nc2n1 +CCOC(=O)c1cnn(C2CCCN(Cc3cnnn3C)C2)c1 +O=C(CN1CCN(Cc2ccccc2)CC1)c1ccc2c(c1)CCC2 +COCCCC(=O)C(C#N)c1ncc(C(F)(F)F)cc1Cl +CCOc1ccc(C(=O)CCC(=O)Nc2ccc(C)cc2O)cc1 +CCOC(=O)c1ccoc1CSc1nncn1C +CC(C(=O)Nc1ccc(C(N)=O)c(F)c1)c1cccs1 +O=C(NCc1ccc(-n2cncn2)nc1)C1CC(=O)N(CC2CC2)C1 +CN(C)c1oc(-c2ccc(S(=O)(=O)N(C)C)o2)nc1C#N +CS(=O)c1nncn1CC(=O)NCCC1CCCCC1 +O=C(N1CCCC1)N1CCCC(c2ncncc2-c2ccncc2)C1 +CCn1nnc2cc(C(=O)Nc3c[nH]nc3C)ccc21 +CC(C)c1cnc2c(c1SCCO)c(=O)n(C)c(=O)n2C +Cc1cc(C)c(NC(=O)CN(C)C(=O)C2CC2)c(C)c1 +COCCC1(O)CCN(C(=O)c2ccc(Cl)c(F)c2)CC1C +CCCCNC(=O)c1cc(S(N)(=O)=O)oc1C +CCn1c(=O)[nH]c2cc(OC)c(OC)cc2c1=O +Cc1c(CNC(=O)Nc2cc(C(=O)N(C)C)ccc2F)cnn1C +O=C(Nc1ccccc1)c1ccc(N(CCO)CC2CC2)nn1 +CCC(C)C(=O)Nc1cnc2c(cnn2C(C)C)c1 +CC(O)CN1CCN(S(=O)(=O)c2cc(F)cc(F)c2)CC1 +C#CCNC(=O)CCSc1ccc(Br)cc1 +CCN(CCO)c1ncnc(Nc2nc3ccc(C)cc3s2)c1N +O=C(CCc1c(F)cccc1F)NC1CCCNC1=O +Cn1ncc(C#N)c1NCc1cccc(F)c1Cl +CC(C)C(=O)N1CCN(C(=O)C(NS(C)(=O)=O)C(C)(C)C)CC1 +CC(=O)NC(C)(C)c1noc(Cc2cccc(C(F)(F)F)c2)n1 +CCSc1ccc(NC(=O)c2ccc(O)c(Cl)c2)cn1 +CC(C)c1ncc(CN2CCNC(=O)CC2)s1 +CCC(=O)N1CCCN(Cc2nc3cc(Cl)ccc3n2C)CC1 +CC(C)CN(C(=O)CSc1nnc(N)n1C1CC1)C1CC1 +NC(=O)c1ccc(COC(=O)c2ccc(C(F)(F)F)cc2)cc1 +CCC1CN(Cc2nnnn2C2CC2)CCN1CC(C)O +COc1cc(C(=O)NCc2ccncc2)ccc1C +O=C(c1nnn(-c2ccc(Cl)cc2)n1)N1CC(O)C1 +O=C(NCc1nnc2n1CCCCC2)N(CCO)Cc1ccccc1 +Cc1nc(-c2ccc(N3CCN(C(=O)C4CCCC4)CC3)cc2)no1 +C#CCN1CCN(C(=O)NCCc2ccsc2)CC1 +Cc1ccc(SCCC(=O)Nc2nncs2)cc1 +CC(C1COc2ccccc2O1)n1cnc2ccccc2c1=O +CCc1cc2c(Sc3nnc(C(F)(F)F)n3C)ncnc2s1 +CC1CC1C(=O)Nc1ccc(C(=O)OCCn2cccn2)cc1 +COCc1cc(C(=O)NCC(=O)NC(C)(C)C)ccc1F +CCc1ccccc1NS(=O)(=O)c1cccc(C(=O)N(C)C)c1 +Cc1cccc(NC(=O)NCCCn2cnc3ccccc32)c1 +Cc1nc(-c2cccnc2)sc1C(=O)NCc1ccco1 +CCCNC(=O)CCCc1nc(-c2ccc(C)cc2)no1 +Cn1ncc2c(=O)n(CC(=O)NC3CCCCCC3)cnc21 +Cc1cccc(C(=O)N2CCCC2C(=O)NCc2ccco2)c1 +CCOC(=O)C(Cc1ccccc1F)=C(N)C(F)(F)F +Cc1ccccc1SCC(=O)Oc1ccc2c(c1)CCC(=O)N2 +CS(=O)(=O)c1cccc(OCc2ncc(-c3ccccc3)o2)c1 +CCOc1ccc(C(=O)NCC(O)c2ccco2)cn1 +COCc1cccc(C(=O)OCc2nc(N)c3ccccc3n2)c1 +CC(=O)c1cc(CC(=O)N2CCOC(c3ccc(F)cc3)C2)cs1 +COCC(=O)Nc1cccc(NC(=O)N(C)Cc2ccco2)c1 +CCOc1ccc(NC(=O)CNC(=O)c2cccc(C)c2)cc1 +CN1C(=O)CC(C(=O)NCCC(=O)N2CCCC2)C1c1cccnc1 +CSc1cnc(OC(C)(C)C)c(OC2CC2)c1 +COc1ccc(C2(C)CN(C)C(=O)O2)cc1C(C)C +COc1ccc(Nc2ncnc(-n3ccnc3)c2N)cc1 +Cc1[nH]ncc1CCCNC(=O)N(Cc1cccc(F)c1)C1CC1 +CC1C(=O)Nc2ccccc2N1C(=O)c1ccc(Cl)cc1 +O=C(NCc1ccc(Cn2cncn2)cc1)c1ccc(F)cc1F +CCOC(=O)c1cc2cnccc2nc1-c1ccccn1 +Cc1cc(C)c(CNC(=O)N2CCN(Cc3ccco3)CC2)c(=O)[nH]1 +CCC(=O)c1ccc(S(=O)(=O)N(CC)CC)cc1 +Cc1sc2ncnc(NCCCc3cccnc3)c2c1C +CC1CN(C(=O)c2cc(Cl)cc3cccnc23)CC(C)O1 +CN(Cc1ccc(F)c(F)c1)C(=O)NCC(=O)N1CCCC1 +Cc1cccc(-c2ncc(CN(C)C(C)c3cccnc3)cn2)c1 +COc1ccccc1Oc1ccc(C(=O)NC(C)C)o1 +NC(=O)C1CCN(C(=O)CC2Oc3ccccc3NC2=O)CC1 +O=C(OCc1nc(-c2ccccc2)no1)c1cccs1 +CC(=O)NCCNC(=O)c1cc(NC(C)=O)ccc1F +COc1ccc(NC(=O)NCc2ccnn2C)cc1OC1CCCC1 +COC(=O)CSc1nccc(-c2cccs2)n1 +O=C(Nc1nnc(C2CC2)o1)c1ccc(Br)cc1F +Cc1ccc2ncc(C(=O)N(C)C(C)c3ccccc3F)n2c1 +O=C(c1cc2n(n1)CCCO2)N1CCN(Cc2ccccn2)CC1 +CN1C(=O)CC(C(=O)Nc2nnc(C3CC3)s2)C1c1ccccc1 +CC(C)CCC(=O)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +CCOCC(=O)N1CCc2[nH]nc(C(=O)NCc3ccccc3)c2C1 +CCc1onc(C)c1NC(=O)c1nc(N2CCCC2)ncc1Cl +Cc1ccc(C)c(S(=O)(=O)N(C)CCc2ccccn2)c1 +CCOC(=O)CCC(=O)Nc1cccc(C(N)=O)c1 +Cc1cc(-c2nnc(NC(=O)c3nn(C)cc3C)o2)n(C)n1 +CCn1nc(C)c(CNC(=O)Nc2cccc(C(=O)NC)c2C)c1C +CCc1onc(C)c1NC(=O)NCc1ccccc1OC1CCC1 +CN(Cc1ccccc1)S(=O)(=O)c1cccc(C#N)c1 +COCCNC(=O)N(C)Cc1cccnc1Oc1ccccc1 +CCCn1c(C)nnc1SCC(=O)NC1(c2ccccc2)CCC1 +CCCn1cc(CNc2ccc(C)c(S(C)(=O)=O)c2)cn1 +CC(=O)Nc1cccc(NCC(=O)NCc2ccccc2Cl)c1 +COCCCNC(=O)C1CC(=O)N(C(C)(C)C)C1 +COc1ccc(NC(=O)NCC(O)c2ccccc2F)cn1 +Cc1coc2c1c(C)cc1oc(=O)c(CC(=O)NC3CC3)c(C)c12 +CN(Cc1ccccc1Cl)C(=O)COc1ccccc1C#N +CCOC(=O)c1sc2[nH]c(CNC)nc(=O)c2c1C +COc1ccc(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)cc1 +O=C(C1COc2ccc(Br)cc21)N(CCO)CC1CC1 +COc1nc(C2CCCO2)nc(NC(C)C)c1N +Cn1c(SCc2cn(-c3ccc(Cl)cc3)nn2)n[nH]c1=O +Nc1cccc(CNC(=O)COc2ccccc2)c1 +CC1(C)CN(C(=O)CCCc2nc3ccccc3s2)CCO1 +CN1C(=O)CCc2cc(C(=O)Nc3cc(-c4ccccc4)on3)ccc21 +CCN(Cc1c[nH]nc1-c1cccnc1)Cc1c(F)cccc1F +Cn1c(C(=O)Nc2cccc(F)c2)nc2cc(O)ccc21 +COCc1ccc(C(=O)NCc2ccc(O)cc2)o1 +COCCNC(=O)c1cnc(N2CCCCCC2)nc1N +Cc1cc(C(=O)NCCCOC(C)C)c2c(C)nn(C)c2n1 +Cc1ccc(C(=O)CCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1 +Cc1nc2n(n1)C(C(=O)Nc1cc(Cl)cc(Cl)c1)CC(=O)N2 +CCOc1ccc(OCC(=O)Nc2cccc(F)c2)cc1 +CCC(C(=O)c1ccc(N)cc1)N1CCc2ccccc2C1 +CCC(CO)N1CCN(C(=O)Nc2ccc3c(c2)C(=O)CCC3)CC1 +O=C(c1ccccc1Nc1ccccc1)N1CCCC1 +CCOC(=O)C(N)c1cc(Br)ccc1OC +CCn1nc(C)c(NCC2CCCN(C(=O)OC(C)(C)C)C2)c1C +CC(C)Oc1ccc(NS(=O)(=O)CC(=O)N2CCCCC2)cc1 +COc1ccc(-c2nonc2NC(=O)c2ccccc2F)cc1OC +CCc1onc(C)c1NC(=O)c1ccc(N(C)C)nc1 +CS(=O)(=O)c1ccc(F)c(NC(=O)CCc2ccc(F)cc2)c1 +O=C(NCc1ccncc1)C1CC12CCN(C(=O)Cc1ccccc1)C2 +COc1ccc(F)cc1NC(=O)NCC1(C)CCC1 +COc1ccc(OC)c(C(=O)Nc2nc(C(C)=O)cs2)c1 +COCCNC(=O)c1cccc(Br)c1N +CC(=O)NCCc1cc(Cl)c2c(c1)OCCO2 +Cc1ccsc1CN(C)C(=O)c1ccc(C#N)cc1 +Cc1ccc(OCCNC(=O)c2cc(C)no2)c(C)c1 +COc1cccc(CNc2nccn(-c3cccc(F)c3)c2=O)c1 +Cc1cc(C(=O)N(C)Cc2cccc(O)c2)c2ccc(F)cc2n1 +COc1ccccc1C(N)C(=O)N(C)Cc1cccs1 +Cc1ccc(NC(=O)CSc2nnc(C(F)(F)F)n2C)c(C)c1 +CCS(=O)(=O)NCC1CCN(S(=O)(=O)c2ccccc2)CC1 +CC(C)(C)NC(=O)c1ccc(NC(=O)C(C)(C)C)cc1 +CC(=O)Nc1cccc(-c2nc3cnccc3o2)c1 +Cc1nnc(SCc2c(F)cccc2Cl)n1CC(N)=O +Cc1nc2ncnn2c(C)c1CCC(=O)Nc1ccc(F)cc1Cl +Cc1sc(=O)n(CC(=O)N2CCCC2c2ccc[nH]2)c1C +c1ccc(-n2nnnc2CSc2ncccn2)cc1 +Cc1cc(C(=O)Nc2ccc(CN3CCOCC3)c(Cl)c2)on1 +Cc1ncncc1C(=O)N(C)Cc1ccc(Oc2ccccc2)cc1 +CSc1nnnn1-c1ccc(C(=O)Nc2ccc(C)cc2)cc1 +O=C(Nc1ccc2nc(C3CC3)sc2c1)C1CCCO1 +CC1CC1C(=O)NCCC(=O)N1CCC(CO)CC1 +Cc1cc(NC(=O)CN2CCn3c(nnc3C3CC3)C2)n(C)n1 +CC(=O)Nc1ccc(Cl)cc1OC(F)(F)F +Cc1ccccc1CN(C)C(=O)Nc1ccc2c(c1)NC(=O)CS2 +CCC(C)NC(=O)Cn1nc(C)n2nc(-c3ccccc3)cc2c1=O +COCCN(C)C(=O)Cc1cc(Cl)c2c(c1)OCCO2 +CCN(CC)C(=O)CCC(=O)N1CCN(Cc2ccccn2)CC1 +Cc1n[nH]c(C(=O)NCCc2ccccc2Cl)c1Br +CCN(CC(=O)NC(C)C)C(=O)CNC(=O)c1ccc(C)c(C)c1 +O=C(Nc1cn[nH]c1)N(Cc1ccc(C(F)(F)F)cc1)C1CC1 +Cc1noc(C)c1NC(=O)c1cc2c(Cl)cccc2n1C +CCc1nnc(SCC(=O)NC(C)C)n1-c1ccccc1 +CCNC(=O)c1cccc(NCC(=O)Nc2ccccc2F)c1 +CCN(CC)C(=O)c1nc(N2CCCCC2)c2cnn(C)c2n1 +COc1cccc2c1N(C(=O)CC1OC(=O)c3ccccc31)CCC2 +CNC(=O)CCc1cc(C)nc(C2CCCN2c2ncccn2)n1 +Cc1nc(N)nc(-c2ccc3c(c2)CCC(=O)N3C)n1 +COC(=O)CNC(=O)c1ccc(C#CCCO)cc1 +Cc1ccn(-c2ccc(NC(=O)c3n[nH]cc3Cl)cc2)n1 +CNc1nc(-c2cc(C)ccc2OC)ccc1C#N +O=C(NCc1cc(-c2ccc(F)cc2F)on1)c1cccs1 +O=C(CCc1ccc(Cl)cc1)Nc1ccccc1-n1cnnn1 +COC(=O)NCCOC(=O)c1cccc(Cl)c1Cl +Cc1nn(C)c2cn(C(C)C(=O)N3CCCC(C)C3)nc12 +Cn1cnc2cc(C(=O)NCC3(C)COC3)ccc21 +CCCC1CCCN(C(=O)CNC(=O)c2ccoc2C)CC1 +Cc1cc(NC(=O)NC(C)c2cc(C)sc2C)no1 +CSc1ccc(NC(=O)c2ccc3c(c2)NC(=O)CCS3)cc1 +CCS(=O)(=O)N1CCN(S(=O)(=O)c2ccc(C)s2)CC1 +Cc1nc(CC(=O)N(CC(C)(C)C)CC(F)(F)F)cs1 +NC(=O)c1oc2ccccc2c1NC(=O)c1ccoc1 +CS(=O)(=O)NCC(=O)NCc1cccc(NC(N)=O)c1 +CC(C)c1ncc(Cl)c(C(=O)Nc2nc(C3CC3)cs2)n1 +Cc1ccc(NC(=O)C(C)NC(=O)C2CCCC2)c2cccnc12 +Cc1ccc2cccc(NC(=O)N(C)CC3CCCCO3)c2n1 +O=C(Nc1nnc(SCc2ccc(F)cc2)s1)C1CC1 +O=C(Nc1ccncc1)N1CCCC1c1ccccc1 +CC(=O)Nc1ccccc1CN1CCOC(c2cccc(O)c2)C1 +CCc1noc(C)c1C(=O)N1CC=C(c2c[nH]c3ncccc23)CC1 +O=C(NC1CC1)C1CCCN(c2ccc(-n3cccn3)nn2)C1 +COC(=O)c1cc(CNC(=O)Cc2ccc[nH]2)ccc1OC +CC1CCC(C(C)C)C(NC(=O)Cn2ccc(=O)[nH]c2=O)C1 +COc1cc(OC)c(NC(=O)c2sccc2C)cc1F +CC(C)(C)N1CC(C(=O)Nc2ccc(Cl)cc2)CC1=O +O=C(CCCOc1ccccc1)NCc1ccncc1 +Cc1ccc(C(=O)N2CCOCC2)cc1NC(=O)c1cccn1C +COC(=O)c1ccc(CSc2ncc3ccccn23)o1 +COc1ccc(-c2nccn3cc(C(=O)NCC4CC4)nc23)cc1 +CCn1ccnc1CN1CCCN(C(=O)c2ccc(C)s2)CC1 +O=C(OCc1nccn1Cc1ccccc1)c1ccoc1 +CN(C)S(=O)(=O)c1cccc(COc2ccccc2C#N)c1 +Cn1cnc2ccc(NC(=O)c3ccc(-n4cnnn4)cc3)cc2c1=O +Cc1oc(C2CC2)cc1C(=O)NCCn1nccc1C +COc1c(C)cc(-c2nn3c(C4CC4)nnc3s2)cc1C +CNC(=O)COc1cc(CSc2nnnn2C)ncc1OC +COCCCNC(=O)c1ccc2ncnc(N3CCCCC3)c2c1 +O=C(CCc1ccncc1)N(Cc1cccnc1)Cc1cccnc1 +CC(C)C(Nc1ccc2nnnn2n1)c1nc(-c2ccccc2)no1 +CCCC(=O)N(C)CCCc1nc2ccccc2[nH]1 +CCCN1C(=O)C(Cc2ccc(OC)cc2)Oc2cc(O)ccc21 +COc1nnc(-c2ccc(C)c(S(N)(=O)=O)c2)c2ccccc12 +Cn1cc(C(N)=O)c(NCc2cn(-c3ccc(F)c(Cl)c3)nn2)n1 +Cc1ccc(C(=O)Nc2cccc(N3CCCCCC3)c2)cn1 +COC(=O)Nc1cccc(NC(=O)c2csc(C)n2)c1 +O=C(NC1CCc2[nH]ncc2C1)c1ccc2cccc(F)c2n1 +Cn1ccc(NC(=O)NC2CCN(c3c(F)cccc3F)C2=O)n1 +COc1cc(Cl)c(C)cc1NC(=O)CNC(=O)c1cccs1 +Cc1ccc(CCC(=O)NCc2c(C)cc(C)[nH]c2=O)cc1 +CCOc1ccc(Br)cc1C(=O)n1ccnc1 +CCNc1nc(C)nc2c1cnn2-c1ccc(C)cc1 +Cc1ccc(C(=O)N2Cc3nn(C(C)(C)C)c(-n4cccc4)c3C2)cc1 +Cc1nnc(COc2ccc(NC(=O)c3ccncc3)cc2)o1 +O=S(=O)(NCc1ccccn1)c1sccc1Br +FC(F)(F)c1ccnc(Oc2cccc(Oc3ncccn3)c2)n1 +C=CCNS(=O)(=O)c1cccc(C(=O)Nc2cccc(C)c2C)c1 +CCc1cc2c(=O)c(-c3cscn3)coc2cc1O +COc1ccc(Cc2nnc3c(N)ccc(C)n23)cc1 +CCNC(=O)CN(C)C(=O)C1CCCN(S(C)(=O)=O)C1 +CC1CN(C(C#N)c2ccc(C(C)C)cc2)CCO1 +NC(=O)CSc1nc2ccccc2nc1SCC(N)=O +Cc1csc(C2CN(Cc3cc(F)cc(F)c3)CCO2)n1 +CC(C)S(=O)(=O)NCCNC(=O)c1cccs1 +Nc1c(NC2CCCCC2)ncnc1Oc1ccccc1 +O=C(NCCCNC(=O)c1cnn2ncccc12)c1cccc(F)c1 +Cc1ccc(NC(=O)COc2ccc(N)cc2F)cc1C +O=C(C1CCCCC1)N1CCN(CC(O)c2cccs2)CC1 +CN(C)S(=O)(=O)Cc1nc2c([nH]1)CCCNC2=O +COC(=O)c1ccc2c(=O)[nH]c(CCC(C)C)nc2c1 +Cc1ccc(C2NC(=O)NC3=C2C(=O)N(C)C3)cc1 +CN(C)C(=O)N1CCN(CC(O)COCc2ccccc2F)CC1 +O=C(c1c(O)cc(F)cc1F)N1CCc2ccccc21 +Cc1cc(F)ccc1NC(=O)c1c(-c2cccnc2)noc1C +CCCn1c(C)ccc(-c2nnc(NCC(C)C)s2)c1=O +CCN(C(=O)c1cncc(Br)c1)c1ccc(F)c(F)c1 +COC(=O)C(C)NC(=O)C(C)Oc1ccccc1 +C=CCn1c(=O)c2c(nc(-n3nc(C)c(C)c3C)n2C)n(C)c1=O +CCOC(=O)C1CCN(C(=O)c2cc3occc3n2C)CC1 +COc1ccc(NC(=O)c2ccc3c(c2)CCN3C(C)=O)cc1 +Cn1cnc2cc(-c3noc(-c4ccco4)n3)ccc21 +COCCN1CC(C(=O)NC(C)c2cccc3ccccc23)CC1=O +CCOc1ccc(S(=O)(=O)N2CCC(C)CC2)cc1NC(C)=O +CCc1nn2c(=O)cc(CNc3ccccc3CC)nc2s1 +O=C(Nn1cnc2ccccc21)c1nc(N2CCCC2)ncc1Cl +O=C1CCN(C(=O)COc2ccccc2-c2ccccc2)CCN1 +Fc1cccc(CNc2ncnc3c2ncn3C2CCCCO2)c1 +CCC(CC)C(=O)N1CCN(C(=O)CCC2CCCC2)CC1 +CC(=O)Nc1ccc(NC(C)=O)c(NC2OC(CO)C(O)C2O)c1 +O=C1CC(C(=O)Nc2cc(F)c(F)c(F)c2)c2ccccc2N1 +CC(C)(C)C1CCN(S(=O)(=O)NC2CCCCC2CO)CC1 +COc1cccc2c(C(C)(C)O)c3c(nc12)CCC3 +Cc1ccc(NC(=O)Nc2cn(C)nc2C)cc1-n1cnnn1 +CCN(Cc1ccc(Cl)c(Cl)c1)C(=O)C1CCN(C)C(=O)C1 +O=C(NCc1cccc2ccccc12)c1n[nH]c(=O)[nH]1 +COC(=O)c1sccc1NC(=O)c1cc(C(F)(F)F)n(C)n1 +CCOCC(=O)N1CC2CCCC2(COc2cccnc2)C1 +O=C(OCc1ccc(-n2cccn2)cc1)c1cncn1-c1ccccc1 +NC(=O)c1ccc(NC(=O)CCSc2ccccc2Cl)cc1 +Cn1cnnc1-c1cccc(NC(=O)c2ccccc2F)c1 +CCc1cc(CNC(=O)c2cccnc2NC(C)C)[nH]n1 +Cc1c(C(=O)NC2CCSc3ccccc32)cnn1C +O=c1ccn(Cc2nc(-c3ccc(F)c(F)c3)no2)c2ccccc12 +COc1ccccc1OCc1cc(C(=O)NC(C)CO)n[nH]1 +Cc1ccc(NC(=O)CN2CCOCC2C2CC2)cc1F +CC(C)(CNC(=O)c1cccc(F)c1)CNC(=O)c1cccc(F)c1 +Cc1c(C(=O)Nc2ccc(F)cc2-c2ccc(F)cc2)cnn1C +CC(C)(C)Oc1ccccc1NC(=O)c1ccnnc1 +Cc1ccccc1CC(=O)Nc1cnn(CCN2CCOCC2)c1 +CCCC(NC(=O)CNC(=O)C1CCCCC1)c1ccccc1 +C#CCn1nc(C#N)cc1-c1ccc(N(C)C)cc1 +OCc1ccc(-c2nccn2-c2cccc(-n3cncn3)c2)o1 +Cn1ccc(C(=O)Nc2sc3c(c2C#N)CCC3)n1 +CCOC(=O)NCC1c2ccccc2CCN1C(=O)OCC +CC(c1nc(N)nc(N(C)C)n1)N1CCN(C(=O)C2CC2)CC1 +NC1Sc2ccccc2C(=O)C1c1nc2ccccc2[nH]1 +CC(C#N)N(C)C(=O)c1ccccc1Br +CC(COc1ccccc1F)NC(=O)C(C)NC(N)=O +CCc1cc(C(=O)NC2CCCc3c2cnn3C)sc1C +CSc1nc(N2CCCC2)c2cnn(CCNC(=O)C3CC3)c2n1 +CC(C)(C)NC(=O)c1ccc(S(=O)(=O)c2ccccc2)cc1 +COc1ccc(C=C(C)CN2CC3OCCN(C)C3C2)cc1 +CC(C)(C)Oc1cc(CNC(=O)CC2CCOCC2)ccn1 +Cc1ccc(OCCNC(=O)c2ccco2)c(C)c1 +Cc1cccnc1Nc1ncnc(NC(C)c2ccccc2)c1N +CC(C)Sc1cc2c(cc1NC(=O)c1ccco1)n(C)c(=O)n2C +CC(C)(C)OC(=O)N1CC2CCCC(CO)(C1)C2(F)F +CC(C)CC1COCCN1C(=O)c1nccc2ccccc12 +CCCN(C(=O)CC)C1CCc2nc(NC(=O)CC)sc2C1 +CNc1cccc(NS(=O)(=O)c2ccc(F)c(C)c2)c1 +CCN(Cc1cc(-c2cc(OC)ccc2OC)on1)C(C)=O +O=C(NCC1CCCO1)c1cc2sccc2n1Cc1ccccc1 +Cc1ccc(C(=O)Oc2ccc(NC(=O)c3ccccc3)cc2)c(=O)[nH]1 +Cn1cc(-c2ncc(C(=O)OCCOc3ccccc3)s2)cn1 +CC(=O)Nc1sc(C)c(C)c1C(=O)OCc1c(C)noc1C +CCn1nccc1C(=O)Nc1nnc(C2CC2)s1 +O=c1cc(CCc2ccc(Cl)cc2)[nH]c2ccnn12 +COc1cccc(C(=O)N(C)CC(=O)Nc2ccccc2SC)c1 +Cc1ccc(NC(=O)CN(C)S(=O)(=O)C(C)C)cc1 +CCSc1ccc(Cl)cc1NCc1nsc(N(C)C)n1 +CCC(CC)c1nnc(NC(=O)N(C)C(C)c2ccccn2)s1 +CCOC(=O)Cn1nc(C)c2c(C(=O)OC)cc(C)nc21 +O=C(CCS(=O)(=O)c1ccc(F)c(F)c1)Nc1ccccc1F +CCN1CCN(C(=O)c2cn3nc(OC)ccc3n2)CC1 +CCC(CC)NC(=O)c1ccccc1S(=O)(=O)CC +COc1cc(C)ccc1OCC(=O)Nc1ccc(C#N)c(Cl)c1 +Cn1cc(C2CCCN2C(=O)c2cc3c(F)cccc3[nH]2)cn1 +Cc1ccc(C(=O)NCC(C2CCOC2)N2CCOCC2)c(=O)[nH]1 +O=C1CCc2ccc(OCc3noc(C(=O)NCCO)n3)cc2N1 +NS(=O)(=O)c1ccc(CNC(=O)NCc2ccoc2)cc1 +CCn1cc(C(=O)Nc2ccc(OCc3ccncc3)cc2)cn1 +COc1ccccc1N1CCN(C(=O)c2ccnn2C)CC1 +COc1ccc(OC)c(C(=O)CNS(=O)(=O)N(C)C)c1 +Cc1cc(C)n2nc(C)c(C(=O)NC(C)c3cc(C)sc3C)c2n1 +COc1ccc(NC(=O)NCCC(O)c2ccccc2)cc1F +O=C(NCCc1ccsc1)c1ccc(-c2ccco2)[nH]c1=O +Cc1cccc(C)c1NC(=O)CN(C)C(=O)NC1CCCC(C)C1 +Cc1occc1C(=O)NC1CCCC1CNC(=O)OC(C)(C)C +COCCN(C)C(=O)NCc1ccc(OC2CCCC2)nc1 +CCNC(=O)C(C)NC(=O)c1nn(-c2ccc(F)cc2)c2c1CCC2 +CNC(=O)c1cc(Cl)ccc1NC(=O)C1COc2ccccc2O1 +Cc1occc1CN(C)C(=O)CCCc1nc2ccccc2s1 +O=C(Nc1nnc(C(F)F)s1)c1ccc(OCC(F)F)nc1 +Cc1oc(CNC(=O)c2ccoc2)nc1C(=O)N1CCC(C)CC1 +O=C(Nc1ccc(Cl)cc1NC(=O)c1ccco1)c1ccnnc1 +Cc1cn(-c2cc(Cl)ccc2Cl)c(=O)c(C#N)c1C +Cc1c(C(=O)NCC(=O)NC(C)(C)C)cnn1C +Cc1ccsc1CNC(=O)Cn1cnc(C#N)n1 +COc1ccc(N(C)S(=O)(=O)c2ccc(C#N)c(Cl)c2)cn1 +CC(NC(=O)NCCO)c1ccc(OC(F)(F)F)cc1 +O=C(Nc1ccc(CN2CCCC2=O)cc1)C1CC1c1ccccc1 +CC(C)c1csc(NC(=O)C2CCN(CC(F)(F)F)CC2)n1 +O=C(CCCNC(=O)C1CC1)NC1(c2ccc(F)cc2)CCCC1 +Cc1ccc(OCC(=O)N(C)Cc2ccc3c(c2)OCO3)cc1C +COc1ccc(Cn2cnc(C#N)c2C#N)c(Cl)c1 +CCOC1CCCN(C(=O)CCc2c(C)nc3cc(O)nn3c2C)C1 +Nc1nc(N)nc(COC(=O)c2ccccc2N2CCCC2=O)n1 +CCOc1ccccc1CCNC(=O)NC(C)C(=O)N1CCCCC1 +CCn1cc(N)cc1C(=O)NC(C)Cc1cccs1 +Cc1cc(C)cc(NC(=O)C2CC(=O)N(C3CC3)C2)c1 +COc1ccc(CC(=O)N2CCCN(c3ccccc3C#N)CC2)cc1 +CN(C)C(=O)CCc1ccc(NCC(=O)N2CCCCC2)cc1 +COc1cccc(OCc2nc(C(=O)N(C)C(C)C)co2)c1 +Cc1nc2cc(NC(=O)CCNC(=O)c3cccs3)ccc2[nH]1 +CC(=O)NCCNC(=O)NC1CCCc2c1cnn2C +COCCC(=O)Nc1ccc(Cl)cc1OCC(F)(F)F +Cc1cc(CNC(=O)NCCc2ccccc2C(F)(F)F)no1 +Cc1sc2ncn(CC(=O)N3CC(C)OC(C)C3)c(=O)c2c1C +CC(C)CC(=O)NCCn1ccc(-c2ccncc2)n1 +Nc1cccc2ccnc(C(=O)Nc3cc(F)ccc3F)c12 +COc1ccc(NC(=O)N2CCC(Oc3ccccc3)CC2)cc1F +CCCC1CN(C(=O)Cc2coc3cc(OC)ccc23)CCO1 +CCCOc1ccccc1NC(=O)c1cccc(C#N)c1 +O=C(c1cc(F)ccc1F)N1CCN(c2ccccc2)CC1 +Cc1csc(C(=O)N2CCN(Cc3c(C)noc3C)CC2)c1 +CCC(CC1CCCC1)C(=O)NCC(=O)Nc1cccnc1 +COc1ccc(-c2nnc3sc(-c4cc(C)on4)nn23)cc1 +CN(C)S(=O)(=O)N(Cc1ccco1)Cc1ccco1 +CCC(C)NC(=O)c1ccc(NC(=O)NCC(O)c2ccco2)cc1 +O=C(Cc1cccs1)NCCNC(=O)c1ccc2cnsc2c1 +O=C(COc1ccccc1F)N1CCCCC1c1cc[nH]n1 +COCCNS(=O)(=O)c1ccc(Cl)cc1F +Cc1cnc(CCNCc2csc(-c3ccsc3)n2)s1 +COc1ccc(-c2[nH]nc3c2C(c2ccccn2)N(C)C3=O)cc1 +Cc1sc2nc(-c3ccc4c(c3)OCCO4)c(CC#N)n2c1C +Cn1c(C2CCCN2C(=O)COC2CCCC2)nc2ccccc21 +CC(=O)Nc1nc(CNc2ccc(-n3cncn3)c(Cl)c2)cs1 +OCc1nnn(Cc2cccc(Cl)c2)c1-c1cccc(F)c1 +CC(C)(c1ccccc1)c1nc2c(c(=O)[nH]1)CCC2 +Cc1oc(C)c(C(=O)NCc2ccc(CN3CCCC3=O)cc2)c1C +CCNc1ncc(C(=O)N2CCN(CCOC)C(=O)C2)s1 +CCN(CCc1ccncc1)C(=O)c1ccc(N)c(C)c1 +Cn1cc(Nc2cccc(C(=O)NC(C#N)c3ccccc3F)c2)cn1 +FC(F)(F)c1cccc(-c2nnc3sc(C4CC4)nn23)c1 +Cc1csc(C(C#N)C(=O)Cc2ccc(F)cc2)n1 +Nc1ccc(F)cc1-c1nc(CCOc2ccccc2)no1 +O=C(NCCCn1cccc1)C(c1ccccc1)c1ccccc1 +CCCNS(=O)(=O)c1ccccc1SCCO +Cc1cccc(C(C#N)NC(=O)Cc2cccs2)c1 +COc1cccc(CNC(=O)Cc2cc(-c3ccccc3F)on2)c1 +Cc1ccc(NC(=O)CNc2ccc(C(=O)N(C)C)c(C)c2)cc1F +O=C(Nc1ccc(Cl)cc1Cl)c1c[nH]c2ccccc2c1=O +C=CCn1c(SCc2cc(O)n[nH]2)nc2sc(CC)cc2c1=O +COc1ccc(-c2cccc(CC3NCCN(C)C3=O)c2)cc1 +CCc1nc(CC(=O)NC(CC)c2cccs2)cs1 +Cn1ccc(CNC(=O)c2cnn3c(C(F)F)cc(C4CC4)nc23)n1 +COC(=O)C1=C(C)Nc2ncnn2C1c1ccc(Cl)cc1Cl +CS(=O)c1ccccc1COC(=O)Nc1cccc(Cl)c1 +COCCNS(=O)(=O)c1ccc(OC)c(NC(C)=O)c1 +CSc1ncccc1C(=O)Nc1ccccc1Br +CCOC(=O)C(C)NCc1cccc(F)c1Cl +COc1cc(C(N)C(F)(F)F)ccc1OC(C)C +Cc1cc(-c2csc(NC(=O)c3ccc(=O)n(C)n3)n2)c(C)s1 +CC(C)n1nccc1NC(=O)CCSc1ccccc1Cl +COCCNC(=O)Cn1nc2c(cc1=O)CCCCC2 +Cc1nc(CNC(=O)Nc2ccc(OC(C)C)c(C#N)c2)c(C)s1 +N#Cc1ncn(Cc2cc(Cl)c3c(c2)OCCCO3)n1 +O=C(Nc1ccc(-n2nccn2)cc1)c1cc2c(s1)CCCC2 +Cc1c(C(=O)NCCC(=O)OC(C)C)cnn1-c1ccncc1 +O=C(NCc1ccc(N2CCCC2=O)cc1)Nc1ccccc1Cl +CCc1ccc(NC(=O)c2ncn(-c3ccc(C)cc3)n2)cc1 +Nc1c(C(=O)CN2CCOCC2C2CC2)c(=O)[nH]c(=O)n1C1CC1 +Cc1nn(CC(F)F)c2[nH]c(=O)cc(C(F)F)c12 +Cc1cc(OCC(=O)Nc2ccn(C)n2)ccc1Cl +Cc1cncc(C2CCN(C(=O)c3scnc3C)CC2)n1 +CC(=O)N1CCc2cc(C(=O)NCc3cscn3)ccc21 +Cc1cc(C)n(C(C)CNC(=O)c2c[nH]c(=O)c3ccccc23)n1 +O=C(NCCCO)NC1CCCc2ccc(F)cc21 +CNC(=O)c1cccc(Cn2c3c(sc2=O)CCCC3)c1 +Cn1nccc1C(=O)Nc1sc2c(c1C#N)CCCCC2 +Cc1nc(C2CCCN(C(=O)C3CC3c3cnn(C)c3)C2)sc1C +O=C(NCc1cc(=O)[nH]c2ccccc12)c1ccc(F)c(F)c1F +CCc1cc(C(=O)NC2CCN(S(C)(=O)=O)CC2)cc(=O)[nH]1 +COc1cccc(CNCc2ncc(-c3cccs3)s2)c1OC +COc1cccc(N(C)c2nc(C)c(CO)s2)c1 +CC(C)(C)CC1CCCN1C(=O)Cn1ccc(=O)[nH]c1=O +Cc1nc(CNC(=O)Nc2ccc(Cl)c(Br)c2)no1 +CC(C)c1noc(CCC(=O)NCC(C)N2CCc3ccccc32)n1 +CCOC(=O)CNC(=O)CNC(=O)c1cc(F)cc(F)c1 +CCCc1nc(CSc2nnc(-c3cccnc3)o2)cs1 +COCCN1C(=O)CCC12CCC(NC(=O)c1cncc(C)c1)CC2 +Cc1nn(C)c(N)c1S(=O)(=O)NCCCn1ccnc1 +O=C(CNCc1ccncc1)N1CCN(Cc2ccccc2)CC1 +CN(C)C(=O)C1CCN(C(=O)CNC(=O)CC(C)(C)C)CC1 +COc1cc(CC(C#N)C(=O)Nc2cccc(C)c2)ccc1O +CCC(C)(CC(=O)OC)NC(=O)Nc1ccccc1N1CCCC1=O +O=C(Cc1n[nH]c2c(Cl)cccc12)NCCCC(=O)N1CCCC1 +CN(CCC#N)S(=O)(=O)N1CCCCC1CCc1ccccc1 +CC(C)(C)c1ccccc1NCC(O)c1cccc(N)c1 +Cc1ccc(CC(=O)Nc2ccc(OCc3nccn3C)cc2)cn1 +Cc1cc(C(=O)NCC(O)c2cccc3ccccc23)c(C)o1 +NC(=O)C1Cc2ccccc2N1C(=O)Cc1ccccc1 +COc1ccc(Br)cc1C1NC(=O)c2ccccc2N1C +CC(C)N1CC(C2NCCc3c(F)cc(O)cc32)CC1=O +CCOC(=O)N1CCC2(CC1)NC(=O)c1ccccc1O2 +Cc1cccnc1NC(=O)c1ccc2c(c1)NC(=O)CO2 +CC1(C)C2CCC1(C)C(Sc1nc3ccccc3[nH]c1=O)C2=O +CCN(CC)C(=O)CC(C#N)c1cccc(Br)c1 +CC(=O)Nc1ccc(F)c(NC(=O)NCCC2CC3CCC2C3)c1 +COCCOC(=O)Nc1ccc(Br)cc1 +CSc1ccc(-c2nn3cc(N)nc3s2)cc1 +Cc1c(CCC(=O)Nc2cc(-c3cccnc3)n[nH]2)cnn1C +Cc1ccc(C(=O)NC2CCOC(C)(C)C2)cc1-n1cnnn1 +Cc1cccc(OCCC(=O)N2CCC(C(N)=O)C2)c1C +Cn1nnnc1-c1cccc(NC(=O)C2(c3ccccc3)CC2)c1 +O=C(NC1CCCC1)c1cc(Cl)c2c(c1)OCCO2 +CCC(=O)Nc1cccc(NC(=O)Cc2ccc(C)nc2)c1 +CCNc1nc(N2CCOCC2)c2ccccc2n1 +Cc1nnc(NC(=O)c2cc(-c3ccc4c(c3)OCCO4)on2)s1 +CC1CN(CCn2c(=O)oc3cccnc32)CC(c2ccccc2)O1 +Cc1cccc2c1N(C(=O)c1ccnc(F)c1)CCC2 +COC(=O)c1ccc(CCNC(=O)Cc2ccccc2)cc1 +COc1ccc(CCc2ncc(C)o2)cc1Br +N#Cc1ccnc(N2CCN(C(=O)c3ccc4c(c3)OCO4)CC2)c1 +CC(=O)Nc1ccc(-c2cn(CC(N)=O)cn2)cc1 +CN(CC1CC1)C(=O)c1cc(-c2ccccc2Cl)[nH]n1 +Cc1cc(N2CCN(C(=O)CCc3ccco3)CC2)nc(C(C)C)n1 +Cc1ccccc1CNc1ccc(S(C)(=O)=O)cc1 +Cc1cc(COC(=O)CCn2cnc3sccc3c2=O)no1 +CC(=O)N1CCc2cc(C(=O)N3CCC(CC(N)=O)CC3)ccc21 +COc1cccc(CNC(=O)NCC2CN3CCCCC3CO2)c1 +O=C(CCc1ncc(-c2c(F)cccc2F)o1)Nc1nncs1 +NC(=O)COc1ccc2ccccc2c1Br +Cn1cc(NC(=O)C2COc3ccc(F)cc3C2)cn1 +O=C(CCCNc1ncccn1)Nc1nc2c(s1)CCC2 +CCn1cc2c(n1)C(COC)CN(Cc1cccnc1)C2 +CCN(CC(C)C#N)C(=O)Cn1cnc(C2CCC2)cc1=O +COC(=O)Nc1ccc(NC(=O)c2csnn2)cc1 +COc1ccc2c(c1)cc(C(=O)NCCc1ccccc1)n2C +CC(C)C(C(=O)NCc1ncn(C)n1)n1nnc(-c2ccccc2)n1 +CC(NS(=O)(=O)c1cccc(Cl)c1)(C(N)=O)c1ccccc1 +CC(=O)c1cccc(NC(=O)N2CCC(CC(N)=O)CC2)c1 +Cc1nc2cc(-c3ccco3)nn2c(N2CCCCC2CCO)c1C +CCCCN(CCC(=O)N1CCNCC1)C(=O)c1ccccc1 +Cc1ccc(C)c(S(=O)(=O)N2CCC(C(=O)NC(C)C)CC2)c1 +O=C(Cc1cccc(O)c1)NCCCNC(=O)c1cccc(F)c1 +CC1CN(CC(=O)N2CCc3ccccc3C2)c2ccccc2S1 +CCC(CC)C(=O)N1CCN(C(=O)COc2ccc(F)cc2)CC1 +Cc1cccc(CCC(=O)NCCNC(=O)c2ccccc2O)c1 +COCCC(=O)NCc1ccc(-c2nc(C)cs2)cc1 +Cc1ccc(C)c(OCCC(=O)Nc2ccccn2)c1 +COc1ccc(C)cc1C(=O)CCC(=O)NCC1CCCO1 +CCCCNC(=O)CN1CCN(C(=O)c2ccc(N(C)C)cc2)CC1 +COc1cccc2cc(CNC(=O)CCc3nc(C4CC4)no3)oc12 +CC(Cn1cncn1)NC(=O)Nc1cnn(CC(F)F)c1 +Cc1ccc(N2C(=O)c3ccccc3NC2c2ccncc2)cc1 +O=C(c1c[nH]c(=O)cn1)N1CCCCC1CCn1cccn1 +Cn1nccc1C(=O)NCc1cccnc1Oc1ccc(F)c(F)c1 +O=C(Nc1nnc(-c2cc(Cl)cc(Cl)c2)o1)c1ccno1 +CN(c1cccc(Cl)c1)S(=O)(=O)c1ccc(N)cc1 +Cc1cc2cc(CNC(=O)c3ccccc3)ccc2[nH]1 +CCCS(=O)(=O)c1ccc2c(c1)NC(=O)C(CC)O2 +O=C(NCc1cccnc1)c1ccc(F)cc1Br +CS(=O)(=O)NCCOC(=O)c1ccccc1F +Cc1ccc2oc3c(c(=O)c2c1)C(c1ccc(F)cc1)N(C)C3=O +O=C1CCCN1c1ccccc1NCc1ccc(OC(F)F)cc1 +CN(C(=O)NC1CC1)C(c1ccc(F)cc1)c1cccnc1 +Cc1c(C(=O)NCCOc2ccc(Cl)cc2)cnn1C +C=CCNC(=O)CC1CSc2ncc(C)c(=O)n21 +COc1cc(Cl)c(S(=O)(=O)NCC(C)C)cc1Cl +CC(=O)N1CCN(C(=O)NC2CC(=O)N(c3ccc(C)cc3)C2)CC1 +CCOC(=O)CNC(=O)c1ccc(N(C)C)c(F)c1 +O=C(CNC(=O)c1cccc2ccoc12)NCc1ccc(F)cc1 +N#Cc1cc2c(n(NS(=O)(=O)c3ccccc3)c1=O)CCCCC2 +Cc1n[nH]c(-c2ccc(NC(=O)C3COc4ccccc4O3)cc2)n1 +COc1cc(C(=O)NCc2nncn2C2CC2)cc(OC)c1OC +Cc1nc(C2CCN(c3noc(-c4ccccc4)n3)CC2)cc(=O)[nH]1 +CC(C)NC(=O)Cc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +Cc1nn(C)cc1C(=O)N1CCN(CCOc2ccccc2)CC1 +COC(=O)CC(NC(=O)c1cc(F)cc(F)c1)c1ccc(OC)cc1 +COC(=O)c1ccc2c(cnn2-c2ccccc2N)c1 +CC(NC(c1ccccc1)c1ccccn1)c1cnn(C(C)C)c1 +Cc1sc2ncn(CCN3CCOC3=O)c(=O)c2c1C +CC(C)(C)OC(=O)N1CC(c2cc(C(F)(F)F)ccn2)C1 +COC(=O)c1cc(-c2ccc(OC)cc2OC)nn1-c1ccccc1 +O=C(Cc1ccccc1)Nc1cccc(NC(=O)Cc2ccccc2)n1 +COC(=O)c1cccc(NC(=O)CNC(=O)c2ccccc2)c1 +O=C(Nc1ccncc1)C1CNCc2ccccc21 +CCCCOC(=O)c1ccc(OC(=O)N2CCOCC2)cc1 +C#CCOC(=O)C(NC(=O)c1ccccc1)=C(C)C +C#CCCOC(=O)c1sc(CC(C)C)nc1C +CC(C)n1nnnc1COc1cccc(C(=O)Nc2ccon2)c1 +O=C(CSc1nncn1CC(F)(F)F)NCc1ccccc1F +COc1cc(CNC(=O)c2cccs2)cc(OC)c1O +O=C(NC1CCCCCC1)c1ccc2[nH]nnc2c1 +Cc1cccc(C(=O)Nc2ccc3c(c2)C(=O)NCC3)c1 +CC(CC(=O)NCC1CN2CCCC2CO1)Cc1cccc(F)c1 +Cc1ccc(OCCC(=O)n2nc(C)cc2C)cc1 +CCOc1ccc(CC(=O)Nc2ccccc2)cc1 +O=C(CSc1nccn1-c1ccccc1)Nc1ccccc1 +N#Cc1ccc(-c2ccc(N)cc2Br)o1 +O=C(NCc1ccccc1OCCO)NC1Cc2ccccc2C1 +CC(C)C1COC(C(C)(C)C2=NC(C(C)C)CO2)=N1 +COC(OC)(OC)C(C)(C)c1ccc2c(c1)CCC(=O)N2 +CC(=O)c1ccc(CNC(=O)C2CCCO2)nc1C +Cc1cc(C)c(NC(=O)Cn2ccc(C(F)(F)F)n2)c(C)c1 +CC(CNC(=O)c1ccnn1C)c1ccc(F)cc1 +Cc1cccnc1CC(C)NC(=O)c1cccc(-n2cccn2)c1 +CC(C)NC(=O)CSc1nnc(-c2ccncc2)o1 +CC(C)(C)C1CCC(O)(CNC(=O)c2ccc3nncn3c2)CC1 +CC(C)CC(CO)NC(=O)c1nc2ccccc2[nH]1 +CN(C)S(=O)(=O)c1cccc(C(=O)N2CCc3ccccc32)c1 +CCc1nnc2sc(-c3cccc(OC)c3)nn12 +CCc1cc(NCCCCc2ccccn2)n2nccc2n1 +Cn1cc(C(=O)N2CCCC2c2ccc3c(c2)OCO3)ccc1=O +O=S(=O)(c1ccccc1)n1ccc2cc(-c3cc[nH]n3)cnc21 +CN1CCc2c(sc3ncn4nc(-c5cccnc5)nc4c23)C1 +CCn1cnnc1CNC(=O)c1ccc(Br)cc1Cl +Cc1ccnc(NC(=O)C2CCC(=O)N(C)C2c2ccccc2F)c1 +CCn1c(CCNC(=O)c2nccc3ccccc23)nc2cccnc21 +CCNc1ncc(CN2CCC(N3CC(C)OC(C)C3)CC2)cn1 +COc1ccc(CCN2CC(NC(=O)C(C)C)CC2=O)cc1 +CNC(=O)NCC(=O)N1CCN(c2ccccc2C#N)CC1 +O=C(Nc1cccnc1)C1CC12CCN(C(=O)Cc1cccs1)C2 +CN1CCOC(CNC(=O)Cc2coc3ccc4ccccc4c23)C1 +Cc1ccc2nc3c(cc(C(=O)N4CCCCC4)n3C)c(=O)n2c1 +CCc1ccccc1NC(=O)c1ccc(OC)c(OC)c1 +CCCc1nnc(NC(=O)N(C)C(CC)CC)s1 +Cc1n[nH]cc1CNC1CCS(=O)(=O)c2ccc(F)cc21 +CC(CNC(=O)NCC1CCN(C)c2ccccc21)c1nccs1 +Cc1ccc(Nc2nc(N)nc(CSc3ncn[nH]3)n2)cc1 +O=C(NCc1cn2ccccc2n1)c1cnccn1 +N#Cc1c(NC(=O)c2ccno2)sc2c1CCCC2 +CN(C)C(=O)N1CCN(C(=O)NCCc2nc3ccccc3[nH]2)CC1 +CN(C(=O)c1cn(C)nc1-c1cccs1)C1CCC1 +CCOC(=O)c1cc(-c2cccc(OC(C)C)c2)nc(N)n1 +CNc1ccnc(-c2cccc(C(F)(F)F)c2)n1 +CCN(CCO)C(=O)Nc1ccc(C(C)=O)cc1 +CCc1nn(C)cc1CNC(=O)Nc1ccc(NC(=O)C(C)C)cc1 +O=C1CCCc2cc(C(O)COc3ccccc3)ccc2N1 +Cc1cccc(-c2nccn2C(C)Cn2nc(C)cc2C)n1 +O=C(CCc1ccncc1)Nc1cccc(N2CCCS2(=O)=O)c1 +CCn1c(SCc2cc(C(=O)OC)c(C)o2)nnc1-c1ccco1 +COc1ccc(C(=O)Nc2cccc(S(C)(=O)=O)c2)cc1 +CCC1CCCCCN1C(=O)c1scnc1C1CC1 +CC(=O)c1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1C +Cc1nc(CCNS(C)(=O)=O)n(-c2ccc3c(c2)CCC3)n1 +CCn1ncc2c(C(=O)NC3CC3)cc(-c3ccccc3)nc21 +N#Cc1ccc(C(=O)NCCNS(=O)(=O)c2ccccc2)cc1 +CC(C)C(=O)NCCNC(=O)c1ccc(C(=O)N(C)C)cc1 +Cc1cc2c(cc1O)C(c1cccnc1F)NCC2 +O=C(Nc1ccc2c(N3CCOCC3)ncnc2c1)c1ccco1 +CCN(C)C(C(=O)NCc1cscn1)c1ccccc1 +CNC(=O)C(NC)c1ccc(-c2ccccc2)cc1 +Nc1cc(NC(=O)CCCOc2ccccc2)ccc1F +COc1cc(NC2CCN(C(=O)c3ccon3)CC2)cc(OC)c1 +COCC1CN(S(=O)(=O)c2cn(C)cn2)Cc2c1cnn2C +CC(C)CC1COCCN1CCn1cc(Br)cn1 +Cc1nc(NC(=O)Cn2c(=O)c(C#N)cn(C3CC3)c2=O)sc1C +COc1ccc(C(=O)N(C)Cc2ccccc2)c(N)c1 +CCc1ccccc1NC(=O)NCc1cn(-c2ccccc2)nn1 +Oc1cc(O)cc(C2NCCc3ccc(Cl)c(F)c32)c1 +CCC1(CO)CCN(C(=O)C(NC(=O)CC(C)C)C(C)C)CC1 +COCc1ccc(C(=O)Nc2cc(F)c(OC)cc2OC)cc1 +COc1ccc(C(=O)NCC(=O)Nc2cc(Cl)ccc2OC)cc1 +CC(=O)c1ccc(NC(=O)N2CCC(c3nc(C)no3)CC2)cc1C +O=C(c1cc(Br)c[nH]1)N1CCN(Cc2ccccn2)CC1 +Cc1cccc(C)c1NC(=O)C1CSc2ncc(C)c(=O)n2C1 +CC(OC(=O)c1ccc(Cc2nc[nH]n2)cc1)c1ccccn1 +CS(=O)(=O)N1CCC(Nc2nccc(N3CCC(O)C3)n2)CC1 +CCOc1cccc(C2Nc3ccccc3C(=O)N2CCCOC)c1 +Cc1cc(Oc2cccc(S(C)(=O)=O)c2)n2ncnc2n1 +CC(C)NC(=O)CCOc1cccc2c1CCC2=O +Nc1ccc2c(c1)N(C(=O)Cc1cccs1)CCC2 +Cc1cc(C)c(-c2cc(C(=O)Nc3cccnc3)[nH]n2)c(O)c1 +CN(Cc1ccc(F)cc1)C(=O)c1cccc(N(C)C)c1 +Cc1cc(C)nc(-n2nc(C)c(CC(=O)OC(C)C)c2C)n1 +CC(C)(NS(C)(=O)=O)C(=O)OCc1cc2c(Cl)cccc2[nH]1 +O=C(OCC1CCCCO1)C1CCCCN1C(=O)c1cccs1 +Cc1cccc(N2CC3(CCN(C(=O)c4ccc(C)nc4)C3)CC2=O)c1 +C#Cc1cccc(NC(=O)c2c(F)ccc(OCC)c2F)c1 +COc1ccc(NC(=O)NC(C)C(C)CO)cc1 +NC(=O)C1CCCN(C(=O)c2ccc3ccccc3c2O)C1 +Nc1c(NCC2CCCO2)ncnc1N1CCN(CCO)CC1 +CC(C)Cc1ccc(S(=O)(=O)N2CCCC(C(N)=O)C2)cc1 +CC(C(=O)NC1CCCC1)N1CCN(Cc2ccc(Cl)cc2)CC1 +O=C(Nc1ccccc1C#CCCO)c1ccsc1 +O=C1NCCN(Cc2cccc3[nH]ccc23)C1c1ccccc1 +COCC(C)(NC(=O)COc1ccc(F)cc1)C(N)=O +Cc1cc(C)cc(NC(=O)C(C)n2ncc3ccccc3c2=O)c1 +CC(C)Oc1ccc(C(=O)Oc2ccc3c(c2)CCC(=O)N3)cn1 +O=C(CCC1CCCC1)Nc1cccnc1-n1cccn1 +CCN1CC2(CCN(c3ncc(OC)cn3)CC2)CC1=O +O=C(NCCCn1ncccc1=O)Nc1ccc(Cl)cc1 +O=c1[nH]cnn1Cc1ccccc1Br +Cc1ccc(S(=O)(=O)N(C)CCCO)cc1C +Nc1nc2c(c(N3CC(CO)CC(CN4CCOCC4)C3)n1)CCC2 +N#CC(C(=O)CCc1ccsc1)c1ccccn1 +Cc1ccnc(-c2ccc(NCc3nc(C)cs3)cc2)n1 +Cc1ccoc1C(=O)Nc1ccc(OCC2CCCO2)cc1 +COc1cc(NC(C)=O)ccc1NC(C)c1cccc(C#N)c1 +CCn1ncc(C(=O)N(C)Cc2nc3cc(C)c(C)cc3[nH]2)c1C +CCn1nc(C2CCOC2)nc1C1CCN(C(C)=O)CC1 +CCOc1ccc(C(C)(C)C)cc1S(=O)(=O)n1ccnc1C +CCOCc1nnn2c1CN(C(=O)c1ccc[nH]1)CC2 +Cc1cc(C)nc(SCC(=O)Nc2cccc3ncccc23)n1 +CC1=NC(=O)C(NC(=O)OCc2ccccc2)C=C1 +CCC(C)Oc1cc(C)ccc1CNC(=O)NCc1ncn(C)n1 +CCOC(=O)N1CCN(C(=O)C2CC=CCC2)CC1 +CCOC(=O)NCCC(=O)Nc1nc(-c2ccccc2)ns1 +C=CCn1c(=O)n(CC=C)c(=O)n(Cc2csc(C)n2)c1=O +CCc1cc(NC(=O)CC2CCCN(C(=O)NCC(C)C)C2)n(C)n1 +COc1cccc(C(=O)N2CCN(C(=O)c3ccc(F)cc3)CC2)c1 +CCCNc1ncnc(Nc2ccccc2F)c1N +Cn1c(=O)n(C)c2cc(C(O)c3ccccc3Cl)ccc21 +CN(C)C(=O)NCC1CC2(CO1)CN(c1nncs1)C2 +CCOC(=O)C(C)(C)N(C)Cc1ccc(S(C)=O)cc1 +O=C(COC(=O)Cc1cccc(F)c1)NCc1ccccc1 +O=S(=O)(Cc1ccccc1)NC1(CCO)CCC1 +O=C(NCC1CCCO1)c1cnn2c3c(cnc12)CCCC3 +Cc1ccc(CC(=O)NCC(c2ccc(C)o2)N2CCOCC2)cc1 +COc1cc(C(=O)N(C)C2CCCCC2)ccc1OC(F)F +O=C(c1ccc(Cn2cccn2)cc1)N1CCOc2ccc(F)cc21 +CCOC(=O)c1cc(C(O)(C(F)(F)F)C(F)(F)F)c(N)o1 +CCOC(=O)CC1CCN(C(=O)c2cnc3ccc(C)cn23)CC1 +COCCNC(=O)CN1C(=O)CNc2cc(C)c(C)cc21 +CS(=O)(=O)NCCn1nc(-c2cccs2)ccc1=O +C=CCN(C)S(=O)(=O)c1ccc(NC(=O)NC(C)(C)C)cc1 +Cn1cnc(CNS(=O)(=O)c2ccc3ccccc3c2)n1 +O=C(NCCc1csc2ncnn12)c1ccco1 +CNC(=O)C1CCN(c2nnnn2-c2ccccc2)CC1 +Cn1cc(N2CCC3(CCCN(C(=O)NC4CC4)C3)C2=O)cn1 +CC1=NC(=O)CC(CNC(=O)C(C)Oc2cc(C)ccc2C(C)C)=N1 +O=C(NCCSc1nc2ccccc2o1)c1cn[nH]n1 +O=C(CSc1nnc2ccc(-c3ccco3)nn12)N1CCCC1 +COCC(=O)N1CCN(C(=O)CCCn2cncn2)CC1 +COc1ccc2c(C)c(C(=O)NCCn3ncccc3=O)oc2c1 +CCC1CN(C(=O)C(C)C)c2cc(C(C)O)ccc2O1 +O=C(Nc1ccccc1C(=O)N1CCCCC1)NC1CCCC1 +CSc1ccc(C(O)CNC(=O)c2c(F)cccc2Cl)cc1 +CCN(CC)C(=O)CNc1ccc(C(=O)N2CCCCCC2)cc1 +CCCCC(=O)Nc1ccccc1N1CCN(C(C)=O)CC1 +CCc1ccc(OC(=O)Cn2c(=O)cnc3ccccc32)cc1 +c1cc(-c2nc(-c3ccsc3)no2)c2[nH]ncc2c1 +O=C(Nc1ccccc1)C1CCCN1C(=O)c1cccc2c1OCO2 +CCC(C)(C)NS(=O)(=O)c1c(C)nn(-c2ccc(F)cc2)c1C +CCCN(CCO)C(=O)C(C)NC(=O)c1n[nH]c2ccccc12 +CCN(CC)C(=O)CN(C)C(=O)CSc1ccccc1 +O=C(Nc1nc2ccc(F)cn2n1)c1cnc2ccccn2c1=O +CCCc1n[nH]c(C2CN(C(=O)C(OC)c3ccccc3)CCO2)n1 +CNS(=O)(=O)c1ccc(CCC(=O)Nc2ccc(F)cc2)cc1 +O=C(Cn1nc(-c2ccccc2)oc1=O)N1CCN(CCO)CC1 +O=C1CC(C(=O)NC(c2ccccc2)c2ccc(Cl)cc2)CN1 +Cc1nn(Cc2ccc(F)cc2)c(C)c1NC(=O)c1cccnc1 +C#CCN1CCN(CC(=O)NCc2ccccc2COC)CC1 +Cc1ccc2ncc(CNc3cnn(C(C)(C)C)c3)n2c1 +Cc1cc(Cl)ccc1NC(=O)CNc1ccc(-n2cncn2)cc1 +Cc1cc(COC(=O)C(C)Oc2ccc(C#N)cc2)on1 +COc1ccc(-c2ccc(N)c(=O)n2CC(C)C)c(OC)c1 +CC(C)c1cc(CN(C)c2nccc(-c3ccccn3)n2)no1 +Cc1ccc(S(N)(=O)=O)cc1NCc1sccc1C +O=c1c(=Cc2ccc(F)cc2)sc2nnc(-c3ccco3)n12 +COc1ccccc1Oc1ccccc1NC(=O)N1CCC(OC)C1 +COC(=O)c1[nH]c(C)c(C(=O)C(C)N(C)C(=O)c2ccccc2)c1C +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)OCc2cc(C)no2)c1 +O=c1c(-c2nc3ccccc3[nH]2)coc2ccccc12 +Cc1ccc(C#N)cc1S(=O)(=O)NCCc1cscn1 +CC(=O)Nc1ccc(NC(=O)c2ccc(Cn3ccnc3)cc2)cc1 +Cc1nc(C(=O)Nc2ccc(Br)cc2F)cs1 +CCC(C)NC(=O)c1cccnc1SCc1ccc(C(N)=O)cc1 +CC(C)CC1COCCN1C(=O)c1cnc2ccccn2c1=O +O=C(Cn1cncn1)N1CCCc2cc(Br)cc(F)c21 +O=C(c1ccc(F)cc1Cl)N(CCO)C1CCCC1 +COc1ccc(-c2nn(CCC#N)c(=O)o2)c2ccccc12 +CCCC(c1ccccn1)N(C)C(=O)c1cccc(-n2ccnn2)c1 +Cc1cc(C)nc(C(C#N)C(=O)Cc2ccc(Cl)c(Cl)c2)n1 +Cc1occc1C(=O)NCCc1nc(-c2ccccn2)cs1 +Cc1csc(NC(=O)C(C)S(=O)(=O)c2ccc(F)cc2)n1 +Cc1ccc(C(=O)N2CCC3(CCC(=O)N(CCO)C3)CC2)cc1O +COc1ccc(CNC(=O)C(C)Sc2nc(C)cc(N)n2)cc1 +NC(=O)c1c(NC(=O)C2CC=CCC2)sc2c1CCCC2 +Cc1cc(NC(=O)C(C)Oc2ccc(C)c(C)c2)no1 +CN(CC(=O)N1CCOCC1)C(=O)c1cccc(-n2cccc2)c1 +Cc1nccn1-c1ncccc1NC(=O)c1cc2ccccc2c(=O)[nH]1 +Cc1cc(C)n(CC2CN(CCN3CCCC3=O)CCO2)n1 +O=C(NCCNC(=O)c1ccoc1)c1ccc(Cl)cc1 +CCOC(=O)CCNC(=O)Nc1cccc(C#N)c1 +Cc1cc(C)n(C(=O)CCc2nc(-c3ccccc3C)no2)n1 +O=S(=O)(c1ccc(Oc2ncccn2)cc1)N1CCOCC1 +Cc1ccc(C(C)Nc2ccc(C#N)cc2N)s1 +CC(C)c1cc(=O)[nH]c2nnc(SCC(N)=O)n12 +CSc1cccc(NC(=O)Nc2cnccc2C)c1 +CSc1ccc(C(=O)NCC(=O)c2ccco2)cc1 +CN(Cc1ccc(F)cc1)C(=O)CC1CC2CCC1C2 +CC(C(N)=O)n1ccnc1Cc1ccc(C(F)(F)F)cc1 +O=C1OCCC1Sc1nnc(-c2ccccc2Br)o1 +N#Cc1ccc(-c2noc(-c3n[nH]c(=O)c4ccccc34)n2)nc1 +CC(C)(C)n1cc(NC(=O)CNC(=O)C2CC2)cn1 +COc1ccc(Cl)cc1NC1CCC(O)CC1 +CC(=O)N1CCC(Nc2ncnc3sccc23)CC1 +O=C(NCc1nc(-c2ccccn2)no1)c1ccccc1N1CCCC1 +CC(C)(C)NC(=O)COC(=O)c1cccc(Cl)c1 +Cc1ccc(F)c(NC(=O)c2ccc(C(N)=O)nc2)c1 +O=C(NCc1cccnc1)c1ccc(N2CCCS2(=O)=O)cc1 +CSc1[nH]nc(NC(=O)c2ccc(C(C)(C)C)cc2)c1C#N +CCOCCCC(=O)Nc1ccc(Cl)cc1N +O=C1CCCN1CCCS(=O)(=O)c1ccc(F)c(Cl)c1 +COc1cccc(-c2nnc(NC(=O)c3ccc(F)cc3F)o2)c1 +Cc1ccccc1OCC(=O)Nc1ccccc1C(=O)N(C)C +CCOC(=O)c1cc(NC(=O)Nc2ccc(=O)n(CC)c2)cn1C +CCn1cc(Br)cc1C(=O)N(CC1CC1)C(C)C +COc1ccc2c(c1)OCC(Cc1ccc(OC)nc1)C2 +CCOc1ccc(C)cc1S(=O)(=O)NC(C)CC +Cc1ccc(CNC(=O)CN2C(=O)CCOc3ccccc32)c(C)c1 +CCC(C)NC(=O)NCC1(c2ccccc2)CCC1 +Cc1n[nH]cc1CNC(=O)c1ccc2[nH]ncc2c1 +Cc1noc(NC(=O)CCc2ccc(Cl)cc2)n1 +CC(=O)NC(C)C(=O)N(C)C(C)c1ccccc1Cl +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1ccc(Cl)c(Cl)c1 +CCNC(=O)c1ccc(NC(=O)C2CC2c2ccc(F)cc2)c(C)c1 +Cn1cc(-c2csc(NC(=O)CCSc3ccccn3)n2)cn1 +Cc1c(C(=O)N2CCC(C(N)=O)CC2)c2ccccc2[nH]c1=O +COc1ccccc1-c1cc(C(=O)N2CCN(C)CC2)no1 +CC(NC(=O)CCN1CCN(C(=O)C(C)(C)C)CC1)c1ccccc1 +Cc1nonc1NC(=O)c1ccc(Br)cc1 +CCCS(=O)(=O)N1CCCc2ccc(NC(=O)CC)cc21 +COc1ccccc1CNC(=O)CCCc1nc2ccccc2[nH]1 +COc1ccc(-c2nc(C(=O)N(C)C(C)C)cs2)c(F)c1 +CCn1ccnc1CN1CCCN(C(=O)c2c(C)noc2C)CC1 +CCS(=O)(=O)N(CC(=O)Nc1ccccc1)c1ccc(OC)cc1 +COc1ccc(-c2ccc3c(c2)C(=O)C(=O)N3)cc1 +Cc1ccc(-c2noc3c(NCCc4ccco4)ncnc23)cc1 +O=C(Nc1ccc(OCc2nnnn2C2CC2)cc1)c1ccco1 +CSc1ncccc1C(=O)N1CCc2c(nc(N(C)C)[nH]c2=O)C1 +CC(O)CNC(=O)NCCOc1cccc2c1OC(C)(C)C2 +CCNC(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +CS(=O)(=O)NCC1OC(CO)C(O)C1N1CCOCC1 +CC(C)n1nnnc1SCc1cccc2cccnc12 +CCn1cnnc1C1CCN(C(=O)c2c(C)oc(C)c2C)CC1 +CN(C)C(=O)CC(NS(=O)(=O)N(C)C)c1ccccc1 +CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(C)cc2F)CC1 +Cc1ccc(CNC(=O)C(C)Sc2nnnn2C2CC2)cc1 +COc1ccc(C(=O)CN2CCOC(C)C2)c(OC)c1 +CCc1nc(C(C)NC(=O)c2ccc(OCC(F)F)nc2)cs1 +CC(=O)c1ccc(OCC(=O)OC(C)C)c(N)c1 +Cc1ccnc(Nc2nc(C)c3cc(C)c(C)cc3n2)n1 +CC(=O)c1cccc(NC(=O)C(C)NC(=O)c2ccccc2)c1 +Cc1ccc2nc(NC(=O)Cn3ncccc3=O)sc2c1 +COc1cc(NC(=O)Cc2cn3ccsc3n2)cc(OC)c1OC +Nc1nnnn1NCc1ccccc1OCc1ccccc1Cl +CN(Cc1cccc(Cl)c1)C(=O)c1cc(Cl)ccn1 +CCOC(=O)c1sc(NC(=O)c2ccc3ncsc3c2)nc1C +Cc1cc(Cl)ccc1NC(=O)N1CCN(C(C)(C)C(N)=O)CC1 +CC(CC#N)N(C)C(=O)CCC(=O)c1ccc(F)cc1F +CC(C)NC(=O)c1ccc2c(c1)nc1n2CCOC1 +CC(=O)c1ccc(Sc2cc(C)nn2C)c(F)c1 +O=C(CCn1ccc2ccc(F)cc21)Nc1nccs1 +O=C(CNc1cccc(Br)c1CO)NCc1ccccc1 +COCc1ccc(C2CCCN2C(=O)Nc2cccnn2)o1 +NC(=O)C1CCCCN1c1ccc(Cl)cc1N +COc1nc2ccccc2cc1-c1noc(-c2cccnc2)n1 +CSc1nsc(NC(=O)N(C)Cc2ccc3c(c2)OCO3)n1 +Cc1cc2nc(C)n(CC(=O)NC3CCCC3)c2cc1C +CC(C)CC1(CNC(=O)c2cc(N3CCCC3=O)ccc2Cl)CC1 +O=C(CCOc1cccc(F)c1)NCCN1CCOCC1 +CCOC(=O)COCCn1cnc2cc(F)c(F)cc2c1=O +CC(C)C(NC(=O)Nc1ccccc1)C(=O)NCC(F)(F)F +CC1(C)C(=O)N(CC(=O)N2CCc3ccccc3C2)c2ccccc21 +CCc1ccc(S(=O)(=O)N2CCCC(CO)C2)s1 +CC(O)CC(C)(C)CNC(=O)N(C1CC1)C(C)c1ccco1 +Cc1nnc(SCC(=O)Nc2ccccc2Br)s1 +CCCCNC(=O)Cn1c(=O)n(C)c(=O)c2ccccc21 +C=CCN(Cc1cccs1)S(=O)(=O)c1sccc1OC +COc1ccc(Cc2nc(C)c(N)c(C)n2)cc1C(C)C +Cc1cc(C(=O)N2CCC(c3oncc3-c3cnccn3)CC2)on1 +Cc1cc(C)c(NC(=O)c2cccc(-n3cccn3)n2)c(C)c1 +Cc1ncoc1C(=O)N1CC2COCC2(c2nnc(C3CC3)o2)C1 +Cc1noc(C)c1CNS(=O)(=O)c1cccs1 +CCn1c(C)nc2cc(C(F)(F)F)c(Cl)cc21 +COc1ccc(S(=O)(=O)n2cc(C)nc2-c2ccccc2)cc1 +CS(=O)(=O)NC1CN(C(=O)CO)CC1C1CC1 +CCOc1cccc(-c2nc3cc(N)ccc3[nH]2)c1O +Cc1nc(C)c(C(=O)NCCc2nc(-c3ccccc3)cs2)s1 +Cc1ccc(Cn2nc(C)c(Br)c2N)s1 +Cc1ccc(-c2cn(CC(=O)NCc3cccnc3)c(=O)o2)cc1 +O=C1C2CCC(CN(Cc3ccccn3)C2)N1Cc1cscn1 +CCc1ccc(O)c(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c1 +CC(C(=O)N1CCCC1)N1CCN(CC(=O)NC2CCCC2)CC1 +Cc1cc(C)cc(C(=O)N(C)Cc2nc3ccccc3c(=O)[nH]2)c1 +CC(C)N1C(=O)C(C)(C(C)C)N(C)c2ccc(N)cc21 +O=C(NCCc1ccccc1)C1CN(C(=O)c2cnccn2)C1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)NC(C)C1CC1 +CCCCOCCN1CCN(c2ccc(Cl)cn2)CC1 +CSc1nsc(NC(=O)c2ccccc2OC(F)F)n1 +CCn1cc(NC(=O)NCc2ccnc(OC)c2)cn1 +O=C(Nc1cccc(F)c1)Nc1cccc(Cn2cncn2)c1 +CC1CN(S(=O)(=O)NCC2(c3ccccc3)CC2)CC(C)O1 +CCOc1ccc(NC(=O)C2CC3CCC2O3)cc1C +Cc1cc(COC(=O)c2ccc3c(c2)OCC(=O)N3)no1 +COC(=O)c1cnc(NC(=O)CCOc2ccc(C)cc2C)s1 +O=c1cc(C2CCC2)ncn1Cc1ccc(F)cc1Br +O=C(NC1CCCCC1)N1CCn2nc(-c3ccccc3)nc2C1 +CN1CCOC(C(=O)NC2CCCOc3c(Cl)cccc32)C1 +CC(=O)NC(C(=O)NC1c2ccccc2CC1O)C(C)C +CC(Oc1ccc(Cl)cc1)c1ccnc2c(C#N)cnn12 +O=C(Cn1cnnn1)Nc1ccc(OCC(F)(F)C(F)F)nc1 +COc1ccc(C)cc1CC(=O)Nc1cccc(NC(C)=O)c1 +Cc1nc(CN(C)C(=O)CCSc2ccccn2)cs1 +Cc1cc(=O)c(C(=O)N2CC(C)(C)C(C)(O)C2)c(C)[nH]1 +CCN(CCO)C(=O)Nc1ccc(S(=O)(=O)C2CCCC2)cc1 +COc1ccc(F)cc1NC(=O)Cn1cnc2c(C)cccc2c1=O +CCCn1ccc(CNc2cc(F)ccc2F)n1 +COc1ccc(F)cc1NC(=O)CNS(C)(=O)=O +CC(C)S(=O)(=O)N(CC(=O)N1CCCCC1)c1ccccc1F +COc1ccc(CNC(=O)N(C)Cc2cccnc2OC)cc1 +CCC(CC)NC(=O)c1ccc(-c2cccs2)[nH]c1=O +Cc1cccc(NC(=O)NCCC(O)C(C)(C)C)c1 +O=C(CSc1nc2cc(F)c(F)cc2[nH]1)Nc1nccs1 +COc1cc(CNS(=O)(=O)N(C)CCC#N)ccn1 +CCC(=O)Nc1ccc(C)c(NC(=O)NCCO)c1 +Cc1n[nH]c2c1C(c1ccc(Cl)cc1)CC(=O)N2 +Cc1cccc(-n2ccnc2SCC(=O)N2CCCC2)c1C +Cc1nnc(SCc2ccc(F)c(Br)c2)n1N +Cc1cc(F)ccc1NS(=O)(=O)c1ccccc1C#N +CCCN(CCC)C(=O)C1CCN(c2ccc3nnnn3n2)CC1 +Cc1cccc(S(=O)(=O)NCc2nc(C)cc(N3CCCC3)n2)c1 +CCSc1ccc(C(C)NC(=O)NCCNC(C)=O)cc1 +COc1cn(CC(=O)NC2CC2)c(CN2CCOCC2)cc1=O +O=C(NCCC(O)c1cc2ccccc2o1)NCc1cccs1 +COc1ccc(C2CC(C(=O)NC(C)C)N(C)S(=O)(=O)N2)cc1 +CNC(=O)CN(C)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +COc1ccc(N2CCN(Cc3cccc(C)n3)C(C)C2=O)cc1 +CC(OC(=O)c1cccn1C)C(=O)Nc1sccc1C(N)=O +CNC(=O)c1sc(-c2sccc2C)nc1C +COC(=O)c1cccc(S(=O)(=O)Nc2ccc(C)c(F)c2)c1 +CCc1c(C)nn(CC(=O)NC2CC(C(=O)OC)N(C)C2)c1C +CCNC(=O)c1nsc(C(=O)N2CCCC(C)C2)c1N +CCOc1cc2nc(-c3cccc(N)c3)[nH]c2cc1OCC +COc1ccc(C(NC(=O)Nc2cccnn2)C(F)(F)F)cc1 +Cc1cnc(-n2nnc(C(=O)N3CCc4ccccc4C3)c2C)s1 +CCOc1c(Cl)cccc1NC(=O)N1CCNC(=O)C1 +Cc1cccc(C)c1OCC(=O)Nc1ccc(F)c(N)c1 +CC(C)(C)OC(=O)N1CCCC(CNC(=O)c2ccccc2F)C1 +COC(=O)c1cccc(NS(=O)(=O)c2ccc(OC)cc2)c1C +CCOc1cc(CCCN2CCOCC2)cc2c1OCCN2 +CSc1nsc(SCc2nc3ccccc3c(=O)[nH]2)n1 +O=C(CNC(=O)c1ccccc1)NCc1cc(-c2ccco2)on1 +O=C(CCCn1cncn1)Nc1cc(Cl)ccc1N1CCCCC1 +O=C(Nc1n[nH]c(Cc2ccc(F)cc2)n1)c1ccc2nncn2c1 +CC(=O)NCCNC(=O)CCOc1ccccc1F +CC(C)OCCC(=O)Nc1nnc(Cc2cccc(F)c2)s1 +CCc1ccccc1NC(=O)c1cc(S(=O)(=O)N2CCCC2)c[nH]1 +O=C(CSc1ccccc1Cl)NCc1ccco1 +CC(Cc1ccco1)NC(=O)c1nc2ccccc2s1 +CCCn1cc(NC(=O)c2ccccc2C)ccc1=O +O=C(CCC(=O)c1ccc2c(c1)CCCC2)NCC(=O)NC1CC1 +CCC1CN(C)c2ccccc2CN1C(=O)CNC(=O)OC +CN(CC(N)=O)C(=O)c1c[nH]nc1-c1ccc(F)cc1 +Cc1cnc(C(=O)NCc2ccc(Cl)cc2)cn1 +C=CCSc1ccccc1NC(=O)c1ccoc1 +Cn1cc(NC(=O)NCc2cc(Cl)ccn2)cn1 +O=C(NCCc1ccccc1)c1cc2sccc2[nH]1 +CC(C)(C)c1cc(Cn2nnc3ccccc32)n(CCO)c1 +CCNC(=O)CNC(=O)c1ccn(-c2cccc(C(F)(F)F)c2)n1 +COCCN(C)C(=O)c1csc(Cc2ccccc2)n1 +CCN(C(=O)NCc1cccc(C(N)=O)c1)C1CC1 +Cc1c(Cl)cccc1NCC(=O)Nc1cccc(C(N)=O)c1 +COC(=O)CCC(=O)Nc1ccc(-c2nc3ccccc3[nH]2)cc1 +N#Cc1c(F)cccc1Oc1ccc(C(=O)NCCO)cc1 +NC(=O)CNC(=O)C(c1ccccc1)N1CCc2ccccc21 +COC(=O)c1ccc(NC(=O)c2cscn2)c(Br)c1 +Cc1ccc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)cc1C +COc1ccc(OC)c(S(=O)(=O)N(C)Cc2sccc2C)c1 +CN(C)C(=O)CN1CCN(C(=O)OC(C)(C)C)CC1 +CC(=O)Nc1nnc(S(=O)(=O)NC(=O)c2ccncc2)s1 +CCOC(=O)Cn1cc(C#N)c(=O)c2cc(C)ccc21 +CC1CCC(NC(=O)c2ccc(OCC(N)=O)cc2)CC1 +Cc1ccc(O)c(C(=O)NCC(=O)Nc2cccc(F)c2)c1 +COc1cccc(C(=O)Nc2ccc3nc(C)[nH]c3c2)c1 +Cc1ccnc2nc(C(=O)NCCc3nc4c(s3)CCCC4)nn12 +COc1ccc(C(=O)NCC(O)c2ccc(C)o2)c(OC)c1 +CNC(=O)c1cccc(NCc2ccc(OC(F)(F)F)cc2)c1 +CC(C)C(NS(=O)(=O)c1ccccc1F)C(=O)Nc1cc[nH]n1 +CSc1ncnc(NCCc2c[nH]c3ccccc23)c1C#N +CCOC(=O)c1c(C)oc(N)c1C(=O)C(C)(C)C +CC(C)N1CCN(S(=O)(=O)N(C)C(C)C)CC1 +CCOCC1CCCN(C(=O)c2ccc(C(C)=O)cc2)C1 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+CCOC(=O)N1CCN(C(=O)c2nnn(-c3ccc(C)cc3)n2)CC1 +CC(NC(=O)CC1(O)CCCCC1)C(=O)N1CCOCC1 +CC(C)(C)NC(=O)CCOc1cccc(Br)c1 +COC(CNC(=O)c1ccc2ccccc2n1)c1cccc(F)c1 +CCc1ccc(C(=O)Nn2cnc3ccccc3c2=O)o1 +O=C(c1ccncc1)N1CCCn2c(CN3CCOCC3)nnc2C1 +CC1=Nc2ncnn2C(=O)C1CCC(=O)Nc1ccc2c(c1)OCO2 +Cc1cnn(CCC(=O)Nc2ccccc2C#N)c1 +Cc1nc(NC(=O)c2cc(F)ccc2F)sc1C +Cn1cnnc1Sc1ccc(NC(=O)c2ccc(F)nc2)cc1 +CCn1cc(C#N)c(=O)n(CC(=O)c2ccc(C)s2)c1=O +CCC1=C(C(=O)OC(C)C)C(c2ccccn2)NC(=O)N1C +Cc1ccccc1OCCn1c(=O)oc(=O)c2ccccc21 +O=C(C1CC1)N1CCC(N2C(=O)c3ccccc3S2(=O)=O)CC1 +O=C(NCCOCC(F)(F)F)Nc1c(F)cccc1F +Cc1ccc(C2NCCc3cc(C)c(F)cc32)cn1 +Cc1ccc(CC(=O)Nc2ccc(N3CCCC3)nc2)cn1 +Cc1nc(-c2ccccc2)ccc1C(=O)NCCc1ccccn1 +CCOC(=O)c1ccc(NC(=O)Cc2c(C)noc2C)cc1 +Cc1cc(N)c2nnc(C=Cc3ccc(F)cc3)n2c1 +CC(NC(=O)Cn1cnnn1)c1ccc(OC(F)(F)F)cc1 +CSc1c(F)cc(NC(=O)N2CCOC3(CCC3)C2)cc1F +COc1ccc(NC(C)=O)cc1S(=O)(=O)NC(C)c1ccccn1 +Cc1n[nH]c(Cc2ccc(N3Cc4ncccc4C3=O)cc2)n1 +COC(=O)CC1CCCCN1C(=O)c1cc(C)c(C)s1 +CCc1cccc(OCc2c(C#N)nnn2CCO)c1 +CCc1ccccc1OCC(=O)NCCC(=O)N1CCCC1 +CCc1noc(CC)c1CNC(=O)NCCc1ccccc1F +O=C(Nc1ccc2c(c1)COC2)c1ccccc1NCc1ccco1 +CCSc1cc(C(=O)Nc2nncs2)ccn1 +Fc1cnc(N2CCCC3(CC(Oc4ncccc4F)CO3)C2)nc1 +CCCC1CN(C(=O)C(C)NS(=O)(=O)c2ccccc2)CCO1 +Cc1nnc(NCc2ccccc2)c2c1nnn2Cc1ccc(F)cc1 +Cc1cc(Oc2ccc(F)cc2)nc(C2CCN(C(=O)C3CC3)C2)n1 +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1ccc(Cl)cc1F +CC(C)c1cc(C(=O)NCCNS(C)(=O)=O)c(O)c(C(C)C)c1 +NS(=O)(=O)c1ccc(NC(=O)Nc2ccc3c(c2)OCCO3)cc1 +Cc1cc(-c2nc(-c3ccc(C#N)cn3)no2)c2c(C)noc2n1 +CC1CN(C(C)CNC(=O)NCCCn2cccn2)CC(C)O1 +Cc1cn2nc(N(C)Cc3ccsc3)sc2n1 +Cc1nc(CNC(=O)Nc2cccc(COCC3CC3)c2)c(C)s1 +CC(Cc1cccnc1)Nc1nc(-c2ccncc2)nc2c1cnn2C +CCC(Oc1ccc(Br)cc1)C(=O)c1cncnc1 +CN(C)C(=O)c1cc(NCC2CCCOC2)ccn1 +CCn1c(C)cc(-c2csc(NCC3CCCO3)n2)c1C +CC1(C(N)=O)CCCN(C(=O)c2cncs2)C1 +CCOc1c(Cl)cccc1NCc1nnc(Cc2ccccc2)o1 +CC(C)NS(=O)(=O)c1ccc(C(=O)Nc2cn[nH]c2)cc1 +CC1Oc2ccccc2N(CCC(=O)N2CCC2)C1=O +Cc1cc(Nc2c[nH]nc2C)nc(-c2ccncc2)n1 +Cc1ccc2ncc(C(=O)N(C(C)C)C(C)C)n2c1 +COc1cccc(C(=O)Nc2ccc3c(c2)CCC3)c1O +CC(C)NC(=O)Cc1ccc(NC(=O)NCc2ncc[nH]2)cc1 +O=C(NCC1CCCO1)c1cc(C2CC2)nc2ccccc12 +COC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1cccnc1 +CN(C(=O)c1cccc(NC(=O)NC2CC2)c1)c1ccccc1F +Cc1nc2ncc(C(=O)Nc3cccc(Cl)c3)c(C)n2n1 +CSc1cccc(NC(=O)Cn2ccc(=O)[nH]c2=O)c1 +NC(=O)CNS(=O)(=O)c1ccccc1C#CCCO +CCCCCNC(=O)CS(=O)(=O)c1nc(C)cs1 +COC(=O)C(CNC(=O)c1ccoc1)Oc1ccc(F)cc1 +Cc1cccc(NC(=O)Cc2nc3ccc(Cl)cc3c(=O)[nH]2)c1 +COc1ccc(-c2nn(-c3ccc(F)cc3)cc2CO)cc1 +O=C(NCC(=O)N1CCCCCC1)c1ccccc1 +NC(=O)c1csc(C(=O)N(Cc2cccnc2)Cc2ccco2)c1 +Cc1c(C(=O)NCCC(C)C)sc2ncnc(N3CCOCC3)c12 +C=CCN1C(=O)C(Cc2ccccc2F)Oc2cc(O)ccc21 +CCC(C)(C)NC(=O)C1CCN(S(=O)(=O)c2cccnc2)CC1 +Cc1oc(-c2cccs2)nc1CC(=O)N1CCC(C(N)=O)C1 +CC1CCCCC1OCCSc1nnnn1C(C)C +CN(CCCOc1ccccc1)C(=O)Nc1ccc(C#N)cc1 +Cc1noc(CCCC(=O)N(C)Cc2ccccc2C)n1 +Cc1cc(NC(=O)C2CC2c2ccc(F)cc2)no1 +CC(C)(C)OC(=O)N1CCC2(CC1)CNC(=O)c1ccccc12 +CCOc1cccc(C(O)CN(C)c2ccccc2)c1 +CCOc1cccc(CNC(=O)Nc2cccc(C(=O)OC)c2)c1 +Cc1ccc(C(=O)Nc2cc(-c3ccccc3)nn2C(C)C)cn1 +CCc1noc(CN(C)Cc2c(C)nn(CC)c2C)n1 +COC(=O)C(Nc1ccc2c(c1)CCCC(=O)N2)c1ccc(F)cc1 +Cc1ccccc1CCC(=O)N1CCc2ccc(N)cc21 +CC1CN(C(=O)c2ccc3c(c2)CCCN3)CCO1 +COCCCNC(=O)CSc1ccc2ccccc2c1 +COc1ncccc1CNC(=O)N1CCC1c1ccccc1 +CSc1ccc(CN(C)C(=O)c2ccc3c(c2)OCCO3)cc1 +O=C(NCCCn1nc2n(c1=O)CCCC2)c1cc2ccccc2[nH]1 +COc1cc(F)ccc1NC(=O)CNC(=O)C(C)(C)C +CC(NC(=O)c1ccc(OCC(F)(F)F)nc1)c1cccc(F)c1 +COC(=O)C1CCCCN1Cc1ccc(OC)c(OC)c1Cl +CNc1cc(C(=O)NC(c2cccnc2)c2cc(C)ccc2C)ccn1 +O=C(Cc1noc2ccccc12)NCc1cccc(Cl)c1 +Cc1cccc(C)c1OCCn1c(=O)c(C#N)cn(C2CC2)c1=O +Cc1sc(=O)n(CC(=O)Nc2nc3c(s2)CCC3)c1C +CCN1C(=O)CCCC12CCCN(C(=O)Nc1ccc(OC)cc1)C2 +CCC(C(=O)N1CCC(c2n[nH]c(=O)n2CC)CC1)n1cccn1 +Nc1ccc(Cl)c(NC(=O)COCC2CC2)c1 +Fc1cccc(CSc2nnc(-c3ccncc3)o2)c1 +Cc1ccccc1OCCN(C)S(=O)(=O)c1ccccc1 +CCc1c(C)nc(-n2nc(-c3ccco3)cc2NC(C)=O)[nH]c1=O +COC(=O)Cn1cnc2c(cnn2-c2ccccc2C)c1=O +O=C(Nc1ccccn1)NC1CCN(c2ncccn2)CC1 +CCCCC(=O)Nc1cc(NC(=O)CC)ccc1OC +Cc1c(NCC2CC=CCC2)cccc1S(N)(=O)=O +CC(CCc1ccccc1F)C(=O)N(C)C1CCN(C)C1=O +Cc1cccc(-n2ccnc2SCC(=O)c2cnn(C)c2)c1 +C=CCNC(=O)CNc1cccc(C(=O)N2CCCCCC2)c1 +CC(C)c1nnc(SCCC(=O)Nc2ccc(Cl)cc2)o1 +CCC(=O)N1CCCN(C(=O)Nc2cccc(C)c2C)CC1 +CC1COc2c(N)cc(-c3ccccc3)cc2NC1=O +Cn1cnc(CNC(=O)NC2(c3cccc(Cl)c3)CCCC2)n1 +COc1ccc(C(C)N(C)C(=O)c2cnc3ccc(C)cn23)cc1 +CCc1cc(C(=O)Nc2c(C)nn(Cc3ccccc3)c2C)no1 +CN(C)c1cccc(C(=O)Nc2ccccc2SCCC#N)c1 +CN(CCCOc1ccc(F)cc1)C(=O)c1cc(F)cc2[nH]cnc12 +Cc1cccc(CNC(=O)CCCN2CCOC2=O)c1 +Cc1cc(C)n(C(C)C(=O)NC(Cn2cncn2)c2ccccc2)n1 +COc1ccc(-c2ccc(CO)c(=O)[nH]2)c(OC)c1OC +CC1CC1C(=O)N1CCN(c2ccc(Cl)cc2)CC1 +CCC(C)C(C)NC(=O)NCC(C)Cn1cccn1 +O=C(Nc1ccc(F)cc1)Nc1ccc(C(=O)N2CCCCC2)cc1 +Cc1cccc(NC(=O)CCc2c[nH]c3ccccc23)n1 +Cc1c(C(=O)NC2CCSc3ccccc32)oc2c1C(=O)CCC2 +CC(OC(=O)c1ccccc1S(C)(=O)=O)C(=O)c1ccccc1 +CC1CC(C)CN(C(=O)C(C)Sc2nncs2)C1 +Cc1cc(C)c(C#N)c(SCC(=O)NCc2ccc(Cl)cc2)n1 +COc1ccccc1CCNCc1ncc(-c2ccco2)s1 +CCCOc1cccc(CNc2cnccc2C#N)c1 +Cc1ccccc1CNc1cccc(NC(N)=O)c1 +Cc1ccc(S(=O)Cc2ncc(-c3cccs3)o2)cc1 +CC(=O)NC(C(=O)Nc1ccc2c(c1)nc1n2CCCCC1)C(C)C +O=C(c1cccs1)N1CCN(CCc2ccncc2)CC1 +O=C1COc2ccc(NC(=O)c3cccc(-n4cccn4)n3)cc2N1 +Cc1ccc(C(=O)NCCCc2c(C)noc2C)s1 +C=CCN(CC=C)C(=O)C(C)NC(=O)C1CC1C +Cc1cc(C)nc(N2CCCC(c3cccc(C(N)=O)n3)C2)n1 +NS(=O)(=O)c1cc(F)c(NC(=O)CC2CC2)c(F)c1 +O=C1CCCc2[nH]c(=O)c(C(=O)N(Cc3ccco3)C3CC3)cc21 +Cc1ncccc1Oc1ncnc(N2CCC(O)(CO)CC2)c1C +CCn1c(C)cc(C(=O)NCC2CC=CCC2)c1C +COC(=O)N1CCC(CNC(=O)COc2ccccc2C)CC1 +O=C(CSc1ccccc1F)Oc1ccccc1 +Cn1ccc(C2CCCCCN2C(=O)c2c(Cl)cnn2C)n1 +CC1(C(=O)NCc2ccc3c(c2)OCO3)Oc2cccnc2NC1=O +O=S(=O)(N1CCOc2ccccc2C1)N1CCCC1c1ccco1 +CC(CCc1ccc(O)cc1)NC(=O)Nc1ccc2c(c1)COC2 +Nn1c(SCC(=O)N2CCCCCC2)nnc1-c1ccccc1F +CCc1c(C(=O)N2CCN(C(C)=O)CC2)cnn1Cc1ccccc1 +CC(=O)c1ccccc1-c1c(C)c2ccccc2[nH]c1=O +Cc1nc(CN(C)C(=O)Nc2cnc(-c3ccccc3)nc2)no1 +O=C(NCc1nnc2ccccn12)c1cc2c(cc1O)CCCC2 +COc1ccc(NC(=O)N2CCCC2C(C)C)cc1NC(C)=O +Cc1csc(C(C)n2ccnc2-c2cc3c(cc2C)OCCO3)n1 +CCCc1ccc(-c2nccn2CCn2cc(C)nn2)o1 +Cc1c(F)cccc1NC(=O)C(C)NS(=O)(=O)c1cnn(C)c1 +COc1ccc(OC)c(-c2csc(NC(=O)c3ccoc3C)n2)c1 +O=C1Cc2cc(NC(=O)c3cc(F)c(Cl)cc3Cl)ccc2N1 +CC(C)CN(CC(C)C)C(=O)c1cccc(F)c1F +CC(C)c1noc2ncc(C(=O)NC(C)c3ccncc3)cc12 +CC(C)(C)C(NC(=O)c1cnn(-c2ccccc2Cl)c1)C(N)=O +COCCCC(=O)NCC(C)c1nc2ccccc2s1 +CCC(NC(=O)NCCc1ccc(F)cc1C)c1ccncc1 +COc1ccc2cnccc2c1-c1cccc(N)c1 +CCCCSc1ncnc2c1ncn2C1CCCCO1 +COC(=O)c1ccc(-n2nnc(CO)c2C(C)(C)C)cc1 +CC1=C(C(=O)OC(C)C)C(c2ccccc2C)NC(=O)N1 +CN(C)S(=O)(=O)c1ccc(F)c(C(=O)Nc2ccc(F)cc2)c1 +O=C(C1CC1)N1CCCC(c2cc(O)nc(-c3cnccn3)n2)C1 +Cn1c(-c2ccco2)nnc1S(=O)(=O)CCCCC#N +Cc1cccc(C(=O)NCC2COCCO2)c1O +O=C(CCc1nc2c(F)cccc2[nH]1)N1CCOCC1C1CC1 +CCc1ccc(CNc2ccc3c(c2)CCC(=O)N3)o1 +Cc1nc(Nc2cc(Cl)cc(Cl)c2)[nH]c(=O)c1CCO +N#Cc1cccnc1SCC(=O)NCc1ccccc1 +CCc1ccc(NC(=O)C(C)OC(=O)c2ccc(C)o2)cc1 +CC(C)(C)c1cnc(CN2CCOCC2C(N)=O)o1 +O=C(C1CC1)N1Cc2[nH]nc(COCc3cccnc3)c2C1 +CCOc1ccc(CN(C)S(=O)(=O)c2ccc(C(C)=O)cc2)cc1 +CCCC1CN(C(=O)NCc2ncn(C)n2)CCO1 +O=C(Cc1nc2ccsc2c(=O)[nH]1)c1ccccc1F +Cc1nnnn1Cc1ncnn1-c1ccc2c(c1)CCC2 +O=C(NCc1ccc(F)cc1)C1CCN1S(=O)(=O)c1ccccc1 +Cc1ccc(CNC(=O)N(C)CC2COc3ccccc3O2)s1 +O=C(C1CCCC1)N1CCOC2CCC1C2OCc1ccncc1 +Cc1cccc(C)c1NC(=O)c1cc(Cl)ccn1 +CC(=O)Nc1cccc(-c2csc(Nc3cc(C)ccn3)n2)c1 +O=C(CCC(=O)c1cccs1)NCC1CCCO1 +Cc1csc(CNC(=O)Nc2cnn(CC(N)=O)c2)n1 +N#CCOc1ccc(NC(=O)Nc2ccccc2F)cc1 +COCc1c(C(=O)Nc2cc(C)cc(C)c2)nnn1-c1ccccc1 +COc1ccc(C(=O)Nc2ccc(SC)cc2)nn1 +COCc1cccc(NC(=O)c2cn3cccnc3n2)c1 +Cc1cc(C(=O)Nc2ccnc3ccnn23)c2c(C)nn(C)c2n1 +O=C(Cn1cnc2c(oc3ccccc32)c1=O)Oc1ccccc1F +Cc1cccc(C(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +NC(=O)c1ccc(OCC(=O)Nc2cc(F)ccc2Cl)cc1 +Cc1cc(C)c2c(C(=O)NCCN3CCNC3=O)cc(C)nc2c1 +N#Cc1c(CCCNc2ccc(C(F)(F)F)cn2)n[nH]c1N +COCCNc1nnc(-c2sc(C)nc2C(C)C)s1 +O=C(c1cccnc1)N1CCCC1CS(=O)(=O)c1ccccc1 +CCc1onc(C)c1NC(=O)NC1CCCCC1(C)C +CC(Cc1nnc(SCC(=O)NC2CC2)o1)c1ccccc1 +Cc1nc(NC(=O)c2cnc3c(cnn3C(C)C)c2)sc1C +COc1ccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)NCC3)c(C)c1 +Cc1cc(C)cc(C(=O)Nc2ccc(S(N)(=O)=O)c(C)c2)c1 +CC(C)N(C)S(=O)(=O)c1cccc(C(=O)NCCCO)c1 +CCCNc1nnnc2c1cnn2-c1ccccc1 +O=C(COc1ccc(Cl)cc1)NCC(O)c1ccccc1Cl +Cc1cc(C)nc(-n2ncc3c2CC(c2ccc(F)cc2)CC3=O)n1 +CC(CCC(C)(C)C)NC(=O)NCC(C)(C)N1CCOCC1 +O=C(NC(c1ccccc1)c1ccc2nc[nH]c2c1)c1ccc[nH]c1=O +CC(=O)N1CCc2cc(C(=O)N3CCCC(C)C3)ccc21 +c1cnc2ccc(Oc3ncnc4ccsc34)cc2c1 +COCCCn1cnnc1S(=O)(=O)Cc1cccc(Cl)c1 +COc1ccc(OC)c(C(=O)Nc2cccn(C)c2=O)c1 +O=C(Nc1cnn(-c2ccccc2F)c1)c1ccccc1 +CCCCCNC(=O)Cn1c(=O)c2c(ncn2C)n(C)c1=O +Cn1cccc1CN(C(=O)NCc1ccccc1)C1CC1 +O=C(Nc1ccc2nc(CCCO)[nH]c2c1)c1ccccc1Cl +CC(C)CCN(C)C(=O)Nc1ccc(N2CCCC2=O)cc1 +CSc1nsc(SCCC(=O)Nc2cc(C)on2)n1 +COc1cc(OC)c(OC)cc1CNc1ccc(C)cc1 +COC(=O)CC(C(=O)OC)c1ccc(OC)cc1 +O=C(C1CC2CN(Cc3cccnc3)CC1O2)N1CCOCC1 +O=c1c2cc(Cl)ccc2ncn1Cc1nc(-c2ccccc2)no1 +COCCC(=O)N1CC(S(=O)(=O)c2ccc(OC)cc2)C1 +O=C1Cc2cccc(C(=O)Nc3ccc4c(c3)CCC4)c2N1 +CCc1c(C(=O)N2CCN(C(C)C)CC2)cnn1-c1ccccc1 +O=c1[nH]c(Nc2ccc(Cl)c(Cl)c2)cc2[nH]cnc12 +COCC(O)CN(C)c1ccc(S(N)(=O)=O)cc1 +CC(=O)c1c(SCC(=O)Nc2ccc(C)cc2)nc(=O)[nH]c1C +CCN(CC)S(=O)(=O)N1CCCC1C(=O)Nc1nccs1 +CC(O)CN1CCN(C(=O)C(C)OCC2CC2)CC1 +Cc1noc(C)c1C(C)NC(=O)Nc1ccncc1 +COc1cc(NCc2ccncc2)nc(C(C)(C)C)n1 +CC(C)N(Cc1ccccc1)C(=O)CCc1cn2cccnc2n1 +CCCCNC(=O)Cn1c(=O)c(=O)n(CC)c2ccccc21 +CC1CCc2sc3nc(N4CCCC4)n4ncnc4c3c2C1 +CC(C)NC(=O)CN1CCN(C(=O)C2CC3CCC2O3)CC1 +CCCN(CC(=O)NC)C(=O)c1c(C)n[nH]c1C +Cc1nc(CN(C)C(=O)c2n[nH]c3ccccc23)cs1 +C#CCOC(=O)c1ccccc1SCC(=O)N1CCCC1 +CCc1ccccc1NC(=O)c1cncc(Br)c1 +CCOC(=O)Cn1nc(-c2ccc(OC)cc2)ccc1=O +CN(CC1(CO)CCC1)C(=O)c1cccc(CCC(C)(C)O)c1 +COc1ccc(C(=O)N2CCN(C(=O)C3CC3)CC2)c(OC)c1 +O=C(c1cc(F)ccc1Br)N1CCC1 +ClC1(Cl)CC1CSc1nncn1C1CC1 +O=C(CCCc1cccs1)N1CCC(c2ccncc2)CC1 +CN(C)S(=O)(=O)c1cccc(-c2ccc(O)cc2)c1 +C=CCNC(=O)NCC1CCN(C(=O)c2cc3ccccc3o2)CC1 +CC(C(N)=O)n1cnc(-c2ccccc2)c1-c1ccc(-c2ccn[nH]2)o1 +Cc1cc(NC(=O)c2ccc(Cl)c(Cl)c2)ccn1 +O=C(NCC(=O)N1CCC2(CC1)OCCO2)c1ccco1 +N#CCCN(Cc1cccc(O)c1)Cc1ccccn1 +O=C(COc1ccc(F)c(Cl)c1)NCc1ccccc1 +Cc1ccc(C(=O)NCC(O)c2ccccc2C(F)(F)F)c(=O)[nH]1 +Cc1cc(C)cc(C(=O)NCC(=O)N(C)CCOc2ccccc2)c1 +Cc1cccc(C2CCCN(Cc3ccncc3)C2)n1 +CC(=O)Nc1ccc(NC(=O)Nc2ccc(F)cc2)cc1 +COCCN(Cc1ccccc1)C(=O)c1ccc(C#N)cc1 +Cc1c2c(cc3c4c(c(=O)oc13)CCC4)CN(CCCO)CO2 +CC1(C)Oc2ccc(NC(=O)c3cn4cccnc4n3)cc2O1 +CCOC(=O)CN(C(=O)c1ccc(N)cc1)C1CC1 +COc1cccc(CNc2cc(CO)ccc2Cl)c1 +CCOC(=O)c1c(C(=O)OCC)c(C)n(N)c1C +O=C(NC1CCCCC1)c1sccc1S(=O)(=O)NC1CC1 +CCC(CCO)NS(=O)(=O)c1cc(C)ccc1C +CC(C)CSc1nnc(-c2cccnc2)n1Cc1ccco1 +CC(C)Cc1nc(C(=O)NCc2nncn2C)cs1 +COc1cccc(C(=O)NCCCn2ncccc2=O)c1OC +COc1cc(C(=O)NC2CCCC2)ccc1OC(F)F +O=C(NCc1ccc(F)cc1)Nc1cc(N2CCOCC2)ncn1 +Cc1ccc(NC(=O)c2ccnc(OC3CCC3)c2)cc1C(N)=O +CCCNC(=O)c1ccc(-n2cc(NC(C)=O)c(C)n2)cc1 +Cc1ccc(C(=O)CCC(=O)N(C2CC2)C(C)C2CC2)s1 +COC(=O)C(C)NC(=O)c1cc2cc(C)ccc2o1 +CC(C)CCNC(=O)c1n[nH]c2c(Cl)cccc12 +O=C(C1CCCc2ccccc21)N1CCCC(n2cncn2)C1 +Cn1c(=O)c2cnc(-c3ccccc3Cl)nc2n(C)c1=O +O=C(Nc1ccc(-n2ncc3ccccc32)cc1)c1cc[nH]c(=O)c1 +COc1cccc(CNC(=O)C(C)Sc2nc(C)cc(N)n2)c1 +CC1COCCN1Cc1csc(C(C)(C)C)n1 +O=C(Nc1ccccc1)C1CCCc2ccccc21 +CCCc1nc(CN2CCOCC2)sc1CO +CC1CCCN(C(=O)c2cc(Cl)c3c(c2)OCCO3)C1 +Cc1oc(COc2ccccc2Cl)nc1CC#N +Cc1noc(C)c1COC(=O)CCCc1nc2ccccc2c(=O)[nH]1 +CNC(=O)C1CCN(c2cc(=O)n3ccccc3n2)CC1 +CN(CC1CCC1)C(=O)Cc1csc(-c2ccoc2)n1 +O=C(Cn1c(=O)n(Cc2ccco2)c2ncccc21)N1CCCC1 +COc1ccc(C(=O)NCc2ccc(Cl)cc2)cc1 +CC(=O)C1(c2ccccc2)CCN(C(=O)c2ccnn2C(F)F)CC1 +Cc1ccc2c(c1)OC(C)CN2C(=O)Cn1nc2ccccn2c1=O +Brc1ccc2cc3c(nc2c1)OCC3 +CC(C)c1cc(C(=O)NCc2ccco2)c2cnn(C(C)C)c2n1 +Fc1cc(-c2ccncc2)ccc1CN1CCOCC1C1CC1 +CC(C)(NC(=O)CCc1ccc(-c2ccccc2)o1)C(N)=O +Cc1cccc(C)c1NC(=O)N1CCCC1c1ccc2c(c1)OCO2 +N#CCCC(CCC#N)(C(=O)c1ccccc1Cl)c1ccccc1 +CC(C)OCCSc1nnc(-c2ccc(F)cc2)n1N +Cc1n[nH]c(C)c1S(=O)(=O)Nc1ccc(Cl)c2cccnc12 +CCC(=O)Nc1nc2cc(NC(=O)c3ccccn3)ccc2s1 +O=C(CSc1nnc(C2CC2)n1C1CC1)c1cc(F)ccc1F +CC(C)C(NC(N)=O)C(=O)Nc1cccc(-c2nncn2C)c1 +Cc1cccc(NC(=O)Nc2ccc3c(c2)oc(=O)n3C)c1C +COc1ccc(C(=O)CCC(=O)NC2CCCC2)cc1Cl +CCC1CCCN(C(=O)c2cccc(COC)c2)C1 +Cc1nn(CCOc2ccc(C#N)cc2)c(C)c1C +CC(C)COCCC(=O)Nc1cccc(-c2nnnn2C)c1 +CC(C)c1c(C2CCN(C(=O)c3cccs3)CC2)noc1N +COC(=O)c1cc(CN(C)C(=O)C2CC3CCC2C3)oc1C +Cc1cc(=O)[nH]c(-c2cccc(NC(=O)Cc3c(C)noc3C)c2)n1 +Cc1ccccc1Nc1ccc(S(=O)(=O)N2CCOCC2)cn1 +COc1ccnc(NC(=O)c2cccc(C)c2C)c1 +Cc1cc(C(=O)NCCN2CCOCC2)nc(N2CCOCC2)n1 +O=C(Nc1ccc(F)cc1Cl)NC1c2ccccc2CC1O +CC(NC(=O)Cc1cccc(OCC#N)c1)c1ccco1 +O=C(c1cc2ccccc2[nH]1)N1CCN(c2ccccc2)CC1 +CCN(Cc1cccc(C)c1)S(=O)(=O)c1ccc2c(c1)OCCO2 +CC(C)C(C)N(C)C(=O)c1ccc(F)cc1Br +O=C(NC1CC1)c1sccc1-c1ccc(F)cc1 +CCn1cnnc1C1CCCCN1C(=O)Cc1ccsc1 +O=C1C(=O)N(CCOCCO)c2ccc(F)cc21 +COc1cccc(CNc2nnnn2C)c1OCc1ccc(C)cc1 +N#Cc1ccc(NC(=O)CCNS(=O)(=O)c2ccccc2)cc1 +Cn1c(SCC(=O)c2ccccc2)nnc1-c1ccc(O)cc1 +CCc1cc(C(=O)N2CCC3(CCCN(CCO)C3=O)C2)cc(=O)[nH]1 +COc1ccc(OC)c2c1CN(C(C)c1nnc(C)o1)CC2O +Cc1cc(C)c(NC(=O)NC(C)c2nnc3ccccn23)c(C)c1 +CC1COCCN1C(=O)CCc1nc2ccccc2s1 +N#Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)OCO3)cc1 +CCn1nc(C)cc1-c1nnc2sc(Cc3ccccc3)nn12 +Cn1ncc(Cl)c1-c1nc(-c2nonc2N)no1 +Cc1cc(C(=O)NCCn2ccc(-c3ccncc3)n2)c(C)o1 +CCCC(C)N1CC(C(=O)Nc2cccc(C)c2C(N)=O)CC1=O +COCCNC(=O)NCCNC(=O)c1ccccc1Cl +OC(CN(Cc1ccccc1)c1ccccc1)c1cccnc1 +COc1cc(OC)cc(C(=O)NCc2nn(C)c3ccccc23)c1 +Cc1ccc(NC(C)C(=O)N2CCOCC2)c(C)c1 +CCn1ccc(-c2ccc(N(C)C)cc2)c(C#N)c1=O +O=C(CN(CC1CCC1)c1ccccc1)NCc1ccccn1 +COCCN(Cc1cccs1)C(=O)Cc1cnc2c(C)cccn12 +O=C(Cc1ccc(Cl)c(Cl)c1)NCC(O)C1CC1 +CCCNC(=O)c1nn(-c2ccc(F)cc2)cc1OCC +CC(C)CN1CCOC(CNC(=O)Cn2cccn2)C1 +COc1cccc(N2CCC(CNC(=O)NCc3ccccn3)C2)c1 +O=C1c2cc(Br)ccc2S(=O)(=O)N1C1CCCC1 +CCCc1c(C(=O)NCC(O)c2ccc(F)cc2)[nH]c(C)c1C(C)=O +COc1cc(OC)c(NC(=O)c2ccno2)cc1Cl +COc1cc(SC)ccc1C(=O)Nc1ncccc1C +CCOC(=O)C1(C(C)C)CCN(C(=O)OC(C)(C)C)CC1 +CS(=O)(=O)c1ccccc1NCc1ccc(-n2cncn2)cc1 +COC1OC(CO)C(O)C(OC)C1NC(=O)c1ccccc1 +CC(C)N1C(=O)CCC1C(=O)NCc1ccc2c(c1)OCO2 +CN(C)C(=O)c1ccc(-c2ccc(C#N)cc2)cc1 +CCOc1ccc(C(=O)NCC2CCCO2)cc1C +Cc1cc(N)cc2c(CC(=O)NCc3ccccn3)noc12 +O=C(CN1CCN(c2ccccc2Cl)CC1)N1CCOCC1 +CC1CN(C(=O)C2CN(C(=O)c3ccc(F)c(F)c3)C2)CC(C)O1 +COc1cc(CN2CC3(CCCC3)CC2=O)cc(OC)c1 +O=C(CN1C(=O)COc2ccc(Cl)cc21)NCc1ccco1 +O=C(NC1CCC(O)CC1)NC(c1ccccc1)C1CCC1 +CNC(=O)CN1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1 +CCC(CO)Nc1ccc(NC(=O)c2cccc(OC)c2)cn1 +CNC(=O)c1ccccc1C#CCNC(=O)c1cccc(C#N)c1 +Cc1ccc(NC(=O)Cc2nnc3cc(-c4nc(C)no4)ccn23)cc1 +COC(=O)CN(c1ccc(OC)cc1)S(=O)(=O)c1ccccc1 +COC(=O)c1c(C)nn2c1ncc1c(=O)n(-c3ccc(C)cc3)ccc12 +Cc1nc(NCC2CN(S(C)(=O)=O)CCO2)c2sccc2n1 +O=S(=O)(NC1CCCc2occc21)c1cccc(F)c1 +O=C(Nc1ccc(SCc2ccc(F)cc2)nn1)C1CC1 +CC(O)CNC(=O)c1csc(-c2ccccc2)n1 +CCC(C(=O)N1CCN(Cc2c(C)noc2C)CC1)c1ccccc1 +C#Cc1cccc(NCc2nc(C(C)(C)C)no2)c1 +CCN(Cc1cccs1)C(=O)CCC(=O)OC +O=C(Cc1cccs1)N1CCC(c2nc3cc(F)ccc3[nH]2)CC1 +O=C(NCC1CCCO1)C1CCCN(C(=O)Nc2ccccc2F)C1 +CCOc1ccc2c(c1OCC)C(c1cnccn1)NCC2 +O=C(CN1CCc2ccccc21)Nc1ccc(F)cc1 +CCn1cc(C(=O)n2ccnc2)c(=O)c2cc3c(cc21)OCO3 +CCOc1cccc(-c2nc(C(=O)NCCOC)cs2)c1 +COc1ccccc1CCNC(=O)NC1CCSc2ccccc21 +O=C(CCc1ccc(=O)[nH]n1)N1CCC(C(=O)N2CCCCC2)CC1 +O=C(Nc1cccc(F)c1)c1cnn2c1CCCC2 +O=C(C#Cc1ccccc1)NCc1ccc(Br)cc1 +O=C(NCC(O)c1ccccc1Cl)c1csc2c1CCCC2 +CCCOC(=O)CNS(=O)(=O)c1ccccc1 +Cc1cccc2nc(C(=O)N(C)C3CCCC3)cn12 +CC(=O)N1CCN(C(=O)c2cc(-c3ccc(F)c(F)c3)n(C)n2)CC1 +CC(=O)N(C)c1ccc(NC(=O)NCC2CC2)cc1 +CC(O)CNC(=O)c1nccc2c(N)cc(F)cc12 +CC(C)n1cnc2cc(CNC(=O)c3cnccn3)ccc21 +CCOc1ccc(C)cc1-c1nc2sc(COC)nn2c1C#N +Cc1cc(NC(=O)CNC(=O)c2ccccc2C)no1 +CCN(Cc1ccccc1)C(=O)c1cc(=O)oc2cc(OC)ccc12 +CCC(=O)NCC(c1ccc(C(F)(F)F)cc1)N1CCOCC1 +CC(C)C(O)C1NCCc2c(Cl)cc(Cl)cc21 +COc1cccc(OC)c1-c1nc2cnn(-c3ccccc3)c2[nH]1 +Cc1nccn1Cc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1 +O=C(NCCc1ccc(-n2cccn2)cc1)NCC(O)c1ccco1 +CC(C)C(CC(=O)NCc1ccncc1)c1ccccc1 +Cc1cc(Cl)ccc1-c1nc(C2CCOC2)no1 +COc1ccc(C(=O)Nc2ccc3c(ccn3CC(C)C)c2)nn1 +COc1cc(C(=O)NC(C)c2ccccn2)ccc1C +CCc1noc(C)c1NC(=O)N1CCCC1CN1CCOCC1 +Cc1nnc(-c2cc(Br)ccc2N)n1C +NC(=O)N1CCCN(CC2(CN3CCOCC3)CCCCC2)CC1 +CCOC(=O)c1nn(Cc2ccc(F)c(Cl)c2)c(N)c1C +CCCCN(C)C(=O)C(O)c1ccc(OC)cc1 +COc1ccc(NC(=O)C(Cc2ccccc2)NC(N)=O)cc1 +CC(C)N(C)S(=O)(=O)N1CCCC1CC(=O)c1cccs1 +Cc1csc(CNC(=O)c2cn(-c3ccccc3Cl)nn2)n1 +CC(Oc1cccc(F)c1)C(=O)NC(C)c1nnc2n1CCCCC2 +CC(Cn1cnc(C2CCC2)cc1=O)c1ccccc1 +Cc1ccc(-c2csc3ncnc(N(C)CC(N)=O)c23)cc1C +N#Cc1cnc2c(ccn2S(=O)(=O)c2ccccc2)c1 +Cc1ncc(CN(C)C(=O)Nc2cccc(Cn3cccn3)c2)s1 +Cc1cc(C)n(-c2ccc(=O)n(CC(=O)NCc3ccccn3)n2)n1 +Cc1nc(CSc2nnc(-c3ccco3)n2CCC(N)=O)cs1 +Cc1ccncc1C(=O)NCC1CCN(c2cnn(C)c(=O)c2)CC1 +CC(C)(C)C(=O)C(N)Cc1ccc(Br)cc1 +COc1ccc(C2=C(C)C(N3CCC(C)CC3)=NS2(=O)=O)cc1 +N#CCCN(Cc1ccco1)C(=O)c1ccccc1F +COC(=O)c1ccccc1CN(C)Cc1nccs1 +CC(C)(C)C(=O)Nc1ccc(C(=O)Nc2nccs2)cc1 +Cc1nnc(N(C)Cc2cccc(C(N)=O)c2)c(C#N)c1C +O=C(CN1CCOCC1C1CC1)Nc1ccccc1N1CCCC1=O +CCc1cc(C(C#N)CC(=O)NC(C)C)ccc1OC +CC1CN(CCCC(=O)Nc2cc(N)ccc2F)CCO1 +O=C(NCc1ccc(Br)cc1Cl)C1CCOC1 +Cc1ccc(Cl)c(OC(C)C(=O)Nc2ccc(C(N)=O)cc2)c1 +COc1ccc(Cl)cc1NC(=O)c1cccc(NC(C)=O)c1 +CC(=O)Nn1cnc2c(sc3ncccc32)c1=O +Cc1ccc(NC(=O)C2Cc3ccccc3C(=O)O2)cc1C +O=C(Cc1nc2ccccc2s1)c1ccc(O)cc1O +CC=CCOC(=O)C1CC(=O)N(c2ccc(F)cc2F)C1 +CC1(C)Oc2ccc(N)cc2N(CCOc2ccccc2)C1=O +Cc1cnc(C(=O)N=c2sccn2Cc2ccccc2F)cn1 +COC(=O)C(C)Sc1ncc(-c2ccccc2)nn1 +CCOC(=O)c1sc(-c2ccc(OC)c(OC)c2)nc1C +COc1ccc(CNc2ccc3cn[nH]c3c2)cc1O +CCN(c1cccnc1)S(=O)(=O)CCCCC#N +O=c1[nH]nc(CN2CCN(c3ccccc3F)CC2)[nH]1 +CC1CN(C(=O)c2csc(-c3cnn(C)c3)n2)c2ccccc21 +Cc1cccc(NC(=O)c2ccc(S(C)=O)cc2)c1C +O=C(NCc1ccc2c(c1)OCO2)c1nc2c(F)cccc2s1 +NS(=O)(=O)c1ccc(NS(=O)(=O)c2cccc(F)c2)cc1 +CCCC(C)NS(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +COC(=O)C(C)NC(=O)Nc1ccc(C)c(Cl)c1 +Cc1ccc(OCCOn2nnc3ccc(S(C)(=O)=O)cc32)cc1 +COc1cc(CNc2c(C)cccc2O)ccc1O +COc1ccccc1CN1C(=O)OCC1C(=O)NCc1cccnc1 +O=C(c1cnc(C2CCCO2)s1)N(CCC(F)(F)F)CC1CC1 +CC(C#N)OC(=O)c1ccc(S(=O)(=O)Nc2ccc(F)cc2)cc1 +COC(=O)c1ccc(OCc2nnc(C3CC3)o2)c(OC)c1 +CC(C)Cc1nnc(C(N)c2c(F)cccc2F)o1 +O=C(CN1CCN(c2ccccc2O)CC1)Nc1cc(F)ccc1F +Cn1cc(S(=O)(=O)N2CCN(Cc3cccc(F)c3)CC2)cn1 +CCNC(=O)CSc1nnc(N2CCCC2)n1Cc1ccco1 +Cc1cc(C)cc(OCCN(C)C(=O)C2CCCN(C(N)=O)C2)c1 +O=C(NCc1ccc2c(c1)OCO2)c1cc2c([nH]c1=O)CCCC2 +O=c1cc(-c2cccnc2)nc(C2CCCN(Cc3ccncc3)C2)[nH]1 +CCc1onc(C)c1NC(=O)C(C)(C)c1cccc(F)c1 +CC(C)(C)c1ncc(NC(=O)c2csnn2)cn1 +Cc1ccccc1CN(C)C(=O)Cc1cn2ccsc2n1 +CCCN(CC1COc2ccccc2O1)C(=O)c1c[nH]c(CC)n1 +CCN(CC(=O)NC)c1cc2nc(C)sc2cc1N +COC(=O)c1sccc1S(=O)(=O)Nc1ccc2c(c1)OCO2 +O=C1CC(c2cccnc2)C2(CCN(c3ncc(F)cn3)CC2)N1 +CCCNC(=O)Nc1cc(S(=O)(=O)N(CC)CC)ccc1C +CCC(NC(=O)NCc1nnc2ccccn12)c1ccc(C)cc1 +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)COC1CCCCC1 +COc1ccc2nnc(CCCC(=O)Nc3ccn(C)n3)n2n1 +O=C(c1cc(F)cc(F)c1)N1CCN(c2ccccc2F)CC1 +Cc1cccc(C(C)C)c1NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +FC(F)n1ccnc1COc1ccc2ccccc2c1 +CCOC(=O)c1sc(NC(=O)c2cn3c(C)cccc3n2)nc1C +COc1cc(C(=O)N(C)Cc2nc(-c3ccccn3)no2)ccn1 +Cc1cnc(C(=O)NC2CCCN(S(C)(=O)=O)C2)cn1 +CN(C)C=Cc1ncc(C(F)(F)F)cc1Cl +O=C(CCCn1c(=O)oc2ccccc21)Nc1nc2ccccc2[nH]1 +O=C(c1cn2cccnc2n1)N(Cc1ccco1)c1ccc(F)cc1 +COC(=O)Cn1ccc(=O)c2ccc(C(F)(F)F)cc21 +Cc1ccc(CCC(=O)N(C)Cc2c(C)nc3sc(C)cn23)o1 +O=C(NCCc1nnc2n1CCC2)c1cc(F)c(F)cc1Cl +CC(C)(C)c1noc(-c2ccc(N3CCNC3=O)cc2)n1 +N#Cc1cccc(COc2ccc(NC(=O)NCCO)cc2F)c1 +CC(=O)Nc1cc(-c2nc(-c3ccncc3)no2)ccc1C +CCN(CCO)C(=O)c1cc(C2CC2)nc2c1c(C)nn2C +Cc1cc(CSc2nnnn2-c2ccc(O)cc2)on1 +Cc1cc(C)c(NC(=O)CSc2nc(C)cc(C)n2)c(C)c1 +Cc1cccc(C(=O)NCCNc2cc(-n3ccc(C)n3)ncn2)c1 +O=C1CC(C(=O)Nc2cccnc2)Oc2ccc(F)cc21 +CCc1onc(C)c1NC(=O)C(C)Oc1ccc(F)c(F)c1 +CCc1ccc(N2CC(C(=O)NCc3ccco3)CC2=O)cc1 +O=C(c1ccc2nncn2c1)N1CCCC1C1CCCC1 +Cc1nc(-c2ccc(NC(=O)C(C)C)cc2)oc1C +Cc1nnc(SCc2ccc(C#N)cc2Cl)s1 +CCC(C)NC(=O)c1onc(-c2ccccc2)c1N +CCc1cccc(NC(=O)N(C)Cc2ccncc2)c1 +COCCn1c(=NC(=O)c2cc(C)n(C)n2)sc2cccc(F)c21 +Oc1cccc2c1CCNC2c1ncccc1Cl +COc1cccc2c1C(Cc1cccnc1)NCC2 +Clc1ccc(NCc2cnn3ccccc23)nc1 +Cc1c(C(=O)NCc2ccnc(OC(C)(C)C)c2)cnn1C +COc1ccc(F)cc1NC(=O)N1CCN(c2ccc(O)cc2)CC1 +N#Cc1nc(-c2ccccc2Cl)oc1NC1CC1 +Cn1ncc2c1CCc1sc(NC(=O)C3CC3)nc1-2 +N#Cc1ccc(C(=O)N2CCN(C(=O)CN3CCOCC3)CC2)cc1 +CCOC(=O)N1CCN(CC(=O)NCC2CCCO2)CC1 +CCc1ccc(C(=O)N2CC3OCCN(Cc4ccccc4)C3C2)o1 +COC(=O)Nc1cccc(OCC(=O)NCc2ccccc2F)c1 +CCOc1ccc(NC(=O)NC(C)c2ccccn2)cc1C +CCn1c2ccccc2n2c(-c3ccc(OC)c(N)c3)nnc12 +O=C(NCC1CCCO1)c1nccnc1-c1nc2ccccc2s1 +CCOc1ccc(NC(=O)c2cccnc2)cc1Cl +CC1NC(=O)C(CO)N(Cc2cccc(Cl)c2)C1=O +COc1ccccc1OCC(=O)NCC(=O)c1ccccc1 +CCc1ccc(C2COCCN2CCC(=O)OC(C)(C)C)o1 +COc1cc(C)c(NC(=O)c2ccc3c(c2)OCCCO3)cc1C +CNC(=O)c1ccccc1NC(=O)C(C)Oc1cccc(C)c1 +CC(O)CNC(=O)c1cnc2sccn2c1=O +COc1ccc(-c2nnc(CC(=O)NCc3ccc(F)cc3)o2)cc1 +COC(=O)c1ccsc1NC(=O)c1ccnc2ccccc12 +O=S(=O)(NCc1cccs1)NCc1ccccc1F +COc1ccc(C(=O)N2CCC(Oc3ccc(F)cc3)CC2)nn1 +CCOC(=O)C(C)(C)n1c(=O)oc2cccc(N)c21 +Cc1nc2cc(F)cc(C(=O)NCc3cn4ccccc4n3)c2nc1C +CCCc1noc(C(C)N2CCN(c3ccccc3)CC2)n1 +CCCOc1cccc(NCc2cn(C)nc2-c2ccncc2)c1 +CCOc1ccc2c(C(=O)NCc3cccnc3)cc(=O)oc2c1 +CC1=C(c2ccccc2)S(=O)(=O)N=C1NCCN1CCOCC1 +Cc1csc(S(=O)(=O)N2CCC(C3=NC=NC(=O)C3)CC2)c1 +Cn1cccc1C1CCCN1C(=O)NCc1ccc2c(c1)OCCO2 +COc1ccccc1CNC(=O)c1cc2cc(F)ccc2n1C +O=C(CCc1nc2sc3c(c2c(=O)[nH]1)CCC3)N1CCCCCC1 +COc1ccc2cc(C(=O)Nc3cc(C)ccn3)c(=O)oc2c1 +COC(=O)C(C)NC(=O)c1ccc(N2CCOCC2)c(F)c1 +CC(=O)C(NC(=O)CN1CCN(c2ccccc2O)CC1)C(C)C +Cc1cc(C(=O)N2CCN(CC(C)O)CC2)c2c(C)noc2n1 +CN1C(=O)COc2ccc(C(=O)NC3CCCCCC3)cc21 +CCCC(NC(=O)c1ccc(C#N)cc1)c1nnc2ccccn12 +CC(=O)NCCNC(=O)c1cccc(CCC(C)(C)O)c1 +CC(C)CSc1nnc(N2CCOCC2)n1CC(C)C +COc1c(F)ccc2c1C(c1cccs1)NCC2 +O=S(=O)(NCc1nc(C2CC2)n[nH]1)c1cccs1 +CC(C)(C)NC(=O)c1cc(=O)[nH]c2ccc(Br)cc12 +O=C(Nc1ccc(OC(F)F)cc1)C1CCOCC1 +Cc1ccc(C)c(C(=O)N(C)C(C)c2ccc(-n3cncn3)cc2)c1 +O=C(OCCc1cccnc1)C1CC(=O)N(Cc2ccccn2)C1 +Fc1ccc(-c2noc3ncnc(NCc4cccs4)c23)cc1 +CC(Sc1nnnn1C(C)C)C(=O)Nc1cc(Cl)ccc1F +CCC(C)(C)NC(=O)CS(=O)(=O)c1ccccn1 +O=C(CCc1ccco1)N1CCN(C2CCc3ccccc3C2)CC1 +Cc1occc1CN(C)C(=O)NC(C)Cc1ccccc1F +O=C(CS(=O)(=O)c1ccccn1)NC1CCCCC1 +CCC(Cn1nc(-c2ccoc2C)oc1=O)NC(=O)CC1CCCC1 +Cc1ccc2c(c1)CCCN2C(=O)c1ccc(-n2nc(C)cc2C)nn1 +CC(=O)C(C)Oc1ccc2c3c(c(=O)oc2c1)CCCC3 +CC(C)C(NC(=O)Cc1ccsc1)c1nc2ccccc2[nH]1 +O=C(NC1CCCCC1)c1cnn2c1SCC2 +Cc1cccc(CNC(=O)NCC2CCCC(C)C2)n1 +Cc1ncc(Br)c(Br)c1Cl +CC(C)N1CC(C(=O)NCc2cn[nH]n2)CC1=O +COc1cccc(-c2nn3c(-c4cnn(C)c4C)nnc3s2)c1 +COc1ccc(S(=O)(=O)Nc2ccccc2F)cc1 +COC(=O)Cc1nn(C)c2c1nnc1c(C(=O)OC)c(C)nn12 +CC(C)Oc1cccc(C(C)NC(=O)CNC(N)=O)c1 +CC(=CC(=O)OC1C(=O)OCC1(C)C)c1ccc(F)cc1F +CCS(=O)(=O)NCCOc1ccc2c(c1)CCC(=O)N2 +Cc1ccc(OCC(=O)Nc2ccc(F)cc2N)cc1 +Nc1ccc(F)c(NC(=O)CCCOC2CCCCC2)c1 +Cc1ccccc1-c1ncc(-c2c(C#N)c(N)nc3c2COCC3)cn1 +CN(Cc1cccc(C#N)c1)C(=O)CCNC(=O)OC(C)(C)C +O=C(NC1CCCCC1)c1ccc(-c2n[nH]c3ncccc23)[nH]1 +CC(=O)c1ccc(NC(=O)Cc2cccc(O)c2)cc1 +Cc1csc(CNS(=O)(=O)c2cnn(-c3ccccc3)c2)n1 +Cc1cc(CC(=O)Nc2c(F)cccc2NC2CC2)no1 +Cc1cc(C(=O)Nc2cc(-c3ccccc3)nn2C)no1 +Cc1cccc(OCC(=O)Nc2ccc3nc4n(c(=O)c3c2)CCC4)c1 +CC1CCC(=O)N1Cc1cc(F)c(Cl)cc1Cl +COc1ccc(F)c(NC(=O)c2sc(S(N)(=O)=O)cc2C)c1 +COc1ccc(COC(=O)c2cccc(N)c2)c(OC)c1 +CC(=O)NC1C(Oc2c(C)cccc2C)OC(CO)C(O)C1O +Cc1ccc(-c2cc(C(=O)Nc3cccnc3-n3cncn3)on2)cc1 +COc1ccc(Cl)cc1CNc1cccc2[nH]ncc12 +N#Cc1ccc(N2CC=C(c3ccc(O)cc3)CC2)nc1 +Cc1cc(NC(=O)C2CCCN(C(=O)c3cccs3)C2)c[nH]c1=O +COc1cc(C#N)ccc1OCC(=O)NCC1CCCCC1 +COCc1cccc(C(=O)Nc2ccccc2C)c1 +Cc1ccc(F)c2c1CCNC2c1cccc(O)c1 +Cc1cn(Cc2ccc(F)cc2)c(=O)c(C#N)c1C +CC(=O)NC1CCN(c2ccc(Br)cc2C#N)CC1 +CNC(=O)CN(c1cc(Cl)ccc1C)S(C)(=O)=O +CC(C)CCNC(=O)c1cc(S(N)(=O)=O)ccc1F +CC(C)(C)OC(=O)N1CCCCC1c1cccc(O)c1 +CC1=CC(C)(C)Nc2ccc(OC(=O)C3CCCO3)cc21 +Cc1cc(S(N)(=O)=O)cc(C(=O)NCc2csc(=O)[nH]2)c1C +O=C(Nc1ccc2c(c1)COC2)NC1CCOCC1 +NC(=O)C1CN(C(=O)CCC(=O)c2ccc(F)c(F)c2)CCO1 +COC(=O)C1CCN(C(=O)C2CC(=O)N(c3ccc(F)cc3)C2)CC1 +Cc1cc(S(C)(=O)=O)ccc1NC(=O)C12CC3CC(CC(C3)C1)C2 +Cc1ccsc1C(=O)N1CCN(C(=O)c2ccccc2)CC1 +Cc1c(C(=O)OC(C)C)sc2nc(C)n(CC#N)c(=O)c12 +O=C(CNC(=O)c1ccc(Br)cc1)NCc1cccnc1 +Cc1nc(COc2ccc3c(C(F)(F)F)cc(=O)oc3c2)oc1C +CCOC1COCC1NC(=O)Cc1nc2cc(Cl)ccc2[nH]1 +O=C(CN1CCN(CCO)CC1)NCC1CCN(c2ccccc2)C1 +Cc1cc(N)cc(S(=O)(=O)NCC2CCC2)c1C +Cc1cc(C(=O)NCc2ccccc2Cl)c2c(C)nn(C)c2n1 +Cc1nc(C2COCCN2C(=O)NC2CCCCC2)no1 +COC(CNC(=O)Nc1ccc(-n2ccnc2)nc1)c1ccccc1 +COC(=O)c1cc(NC(=O)NCc2cnn(C)c2)c(F)cc1F +Cc1ccc(CCNC(=O)NCCc2cc(F)ccc2F)cn1 +Cc1ccccc1NC(=O)c1oc2cccnc2c1N +CC(NS(=O)(=O)c1ccc(C#N)c(Cl)c1)c1ccccn1 +CN(C1CCN(C(=O)COCc2ccccc2)CC1)S(C)(=O)=O +Cc1noc(C)c1-c1ccc(Br)cc1 +CC(OCc1ccco1)C(=O)Nc1cc(Cl)ccc1N +CCCn1nc(C(=O)NCCc2c[nH]c3ccccc23)ccc1=O +CC1CCOCCN1C(=O)Nc1cc(Cl)ccc1Cl +C#Cc1cccc(NC(=O)COc2ccc(F)cc2Cl)c1 +Cc1cc(C(=O)Nc2cnccn2)nn1C(C)(C)C +CN(CCC(F)(F)F)S(=O)(=O)c1ccc2oc(=O)ccc2c1 +CC(C)(C)c1nnc(SCCc2ccc(F)cc2)n(N)c1=O +CCC1CCC(NC(=O)c2cnc3ccccn3c2=O)CC1 +COc1ccc(C2NCCc3cc(C)c(F)cc32)cc1O +N#CCCNC(=O)CSc1cc(F)ccc1F +Cn1cnnc1CNC(=O)c1cc(C(C)(C)C)nn1C +CCOc1cccc(-c2ccc(N)c(=O)n2CCCOC)c1 +CCOC(=O)NCCC(=O)Nc1ccc(C)cc1OC +CC1(C)Oc2ccc(NC(=O)N3CCC(n4cccc4)CC3)cc2O1 +Cc1nc2c(nc(SCc3cccc(F)c3)n2C)c(=O)[nH]1 +O=C(NCc1ccc(-n2cccn2)nc1)C1CC=CCC1 +CCCNC(=O)c1ccc(Cl)c(S(=O)(=O)NC(C)(C)C)c1 +Cc1ccc(N2CCOC3CC(COc4ccccn4)CC32)nn1 +COc1ccc(C(=O)NCc2ccncc2)cc1C +CC1CN(Cc2cnn(C(C)(C)C)c2)C(C)CO1 +Cc1cc(C)n(-c2ccc(NC(=O)Nc3ccc(O)cc3)cn2)n1 +CCc1nc(C)sc1C(=O)N1CCN(c2ccc(C)cc2)C(=O)C1 +Cc1ccc(C(=O)NCc2cnn(-c3ccccc3)c2)s1 +O=C(NC1CCCCC1)C1Cc2ccccc2CN1 +O=C(NCc1cccc(OCCN2CCOCC2)c1)C1CC=CC1 +O=C(Cc1ccon1)Nc1ccc(O)c(C(F)(F)F)c1 +Cc1ccc(C(=O)N2CCC3OC(c4noc(C)n4)CC3C2)o1 +COCCC(NC(=O)c1csc(-c2ccccn2)n1)C(N)=O +O=C(CCc1nc2ccccc2s1)Nc1ccncc1 +O=C(COc1cccc2c1CCC2=O)Nc1ccc(F)cc1Cl +CCC(C)C(NC(=O)Cn1nc2n(c1=O)CCCCC2)C(N)=O +CC(C)(C)OC(=O)NCC1CCCCN1c1cc(C#N)ccn1 +O=C(c1cc(C2CC2)on1)N1CC(c2nc3ccccc3[nH]2)C1 +COCCN(CCC#N)S(=O)(=O)c1cc(F)ccc1C +CCC(=O)Nc1ccc(NC(=O)CCn2nnc3ccccc32)cc1 +CCN(CC)C(=O)CN1C(=O)C(C)Oc2ccc(C(C)=O)cc21 +COc1cccc(C(=O)NCc2ccc(NC(=O)NC(C)C)cc2)c1 +Cc1nc(C)c(C(=O)N(CC2CCCO2)c2ccncc2)s1 +CCc1ccc(C2COCCN2S(=O)(=O)c2ccccc2)o1 +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)N(C)C(C)CC#N +Cc1ccnc(C(NC(=O)c2nnc3nc(C)cc(C)n23)C2CC2)c1 +Cc1ccc(-c2nc(-c3nc(Cc4noc(C)n4)no3)cs2)o1 +CCCC(=O)N1CCCCC1C(=O)N(C)Cc1cccc(C#N)c1 +CCNC(=O)CCCC(O)c1cc(C)ccc1OC +O=c1c2ccccc2ncn1Cc1nc(-c2cccs2)no1 +CC(C)(C)CC(=O)NCC1(N2CCOCC2)CCCCC1 +COc1cc(OC)cc(-c2nc(-c3ccnc(OC)c3)no2)c1 +COc1ccc(C(=O)NCc2nnnn2-c2ccc(F)cc2)cc1 +CC(C)CN1CCN(C)C(=O)C12CCN(Cc1nccs1)CC2 +O=C1CCCN1CCc1nc(-c2cc(F)ccc2F)cs1 +Cc1c(C(=O)N2CCOCC2)cnn1-c1ccc(F)cc1F +CC1(C(=O)NC2(c3ccc(F)cc3F)CCOCC2)CCCO1 +Cc1nc(C)c(C(=O)N2CCC(Oc3cccnn3)CC2)s1 +CCn1ccc(NC(=O)Nc2cc(OC)ccc2OC)n1 +CCc1ccccc1NC(=O)c1ccc(=O)n(Cc2ccccc2)n1 +Cc1nc(SCc2ccccc2)[nH]c(=O)c1CC(N)=O +CCCOc1cccc(C(=O)Nc2c(C)cc(N)cc2CC)c1 +CC(C)c1ccc(NC(=O)c2ccc(N)cc2)cc1 +Cc1c(NC(=O)c2cccc(-c3ccoc3)c2)cccc1C(N)=O +CCC(C)C(NC(=O)CN1CC(C)OC(C)C1)C(=O)OC +O=S(=O)(c1cc(F)cc(F)c1)N1CCN(CC(O)C2CC2)CC1 +Clc1ccc2c(c1)CN(Cc1csc(C3CCCO3)n1)CC2 +Cc1nc(NC(=O)c2ccc(F)cc2Cl)sc1C(=O)N(C)C +CC(=O)Nc1ccc(NC(=O)c2cccnc2N2CCCCC2)cc1 +Cc1sc2ncnc(N(C)CCO)c2c1-c1ccc(F)cc1 +CCN(CC)C(=O)c1cccc(NC(=O)NC(C(N)=O)C(C)(C)C)c1 +CCCNC(=O)Nc1ccccc1-n1cc(Br)cn1 +CCCCCNC(=O)N1CCN(C(=O)c2ccccc2O)CC1 +N#CC1C2C1C1C=CC2n2c(=O)n(-c3ccccc3)c(=O)n21 +COc1ccccc1C#CCNC(=O)COc1ccc(C)cc1 +O=C(Nc1ccc(Br)cn1)c1ccccc1-n1cnnn1 +Cc1ccccc1C(=O)NCCC(=O)OC1CCCC1 +Cc1cc(NC(=O)c2ccc(C(=O)NC(C)(C)C)cc2)no1 +O=C(CCc1ccc(F)c(F)c1)Nc1ccc2c(c1)OCC(=O)N2 +Cc1cc(S(=O)(=O)n2ccnc2)c(C)cc1Br +COCCC1CN(C(=O)CCC(=O)NC2CCCC2)CCO1 +Cc1cc(C)cc(OCCOC(=O)c2ccc(S(N)(=O)=O)cc2)c1 +Cc1cc(N(C)Cc2nccs2)n2nc(C)c(C)c2n1 +CC(C)COc1ccc(NC(=O)Cn2ccnn2)cc1Cl +COc1ccccc1-c1nnc(SCC(=O)NC(C)(C)C)o1 +C=CCCc1csc(C2CN(Cc3ccccc3)CCO2)n1 +Cc1cc(CN2CCc3c(nc(-c4cccnc4)[nH]c3=O)C2)oc1C +Cn1cc(NC(=O)c2cccc(Oc3ccncc3)c2)cn1 +O=C(NCCC(=O)N1CCCCC1)Nc1ccncc1 +Cn1c(C2CC2)nc2cc(NC(=O)CSc3nncs3)ccc21 +Cc1noc2ncnc(SCC(=O)C(C)(C)C)c12 +Cc1ccccc1-c1cncc(C2CCN(C(=O)CO)CC2)n1 +CCc1noc(C2(c3cccc(C(F)(F)F)c3)CCOCC2)n1 +COc1ccc(Cl)cc1CNC(=O)c1cn2cccnc2n1 +C=CCOc1cccc(NC(=O)c2cc(-c3ccncc3)on2)c1 +N#Cc1ccccc1Cn1nc2ccccn2c1=O +COc1ccccc1C(=O)N1CCN(c2nccnc2OC)CC1 +Cc1cc(C(=O)NC(C)CO)c(C)n1C(C)c1ccccc1 +Cc1ccc(Nc2c(C(=O)N3CCOCC3)cnc3ccccc23)cc1 +Cn1c(C(=O)N2CCOCC2C2CC2)cc2ccccc21 +CCCNS(=O)(=O)c1ccc(NC(=O)Cc2ccc[nH]2)cc1 +Cc1cc(NC(=O)N2CCC(CO)CC2)ccc1OCC(F)(F)F +CC(CC(=O)NCc1nc2ccccc2[nH]1)c1ccccc1 +O=C(CCNC(=O)c1cnoc1-c1ccccc1)Nc1ccncc1 +COc1ccccc1-c1nnc2n1C1CN(C(=O)C3CC3)CC1CC2 +CC(C)(C)c1noc(CSc2ccc(N)cc2)n1 +CSc1ccc2c(c1)sc(=NC(=O)c1ccnn1C)n2C +CCCOc1ccccc1-c1cnn(C)c(=O)c1C#N +O=C(c1cnccn1)N1CC2CN(Cc3cccc(F)c3)C(=O)C2C1 +COCC(C)(C#N)NC(=O)CCCn1ccc2cc(Cl)ccc21 +C=CCN(CC=C)C(=O)CSc1ccc(C)cc1 +Cc1cc(C)nc(N2CCN(C(=O)C3CCCN(C(N)=O)C3)CC2)n1 +Cc1nc(-c2c(C)c(C)nn(C)c2=O)sc1C(=O)NCC1CC1 +O=C(CC(F)(F)F)Nc1ccc(CCN2CCOCC2)cc1 +CC(c1ccccc1)N(C)C(=O)Nc1cccnc1 +O=C(Nc1nc(C(F)(F)F)cs1)c1ccccc1O +COc1cccc(C(=O)OCCn2nc(C)cc2C)c1F +CCOc1ccccc1NC(=O)Cc1csc(NC(C)=O)n1 +C=CCNC(=O)C(C)Sc1nccn1-c1ccc(OC)cc1 +N#CC1(NC(=O)COc2ccc(C(N)=O)cc2)CCCC1 +CC(=O)n1cc(Br)c2cc(F)ccc21 +CCc1nnc2n1N=C(C)C(C(=O)Nc1ccccc1)S2 +CC(C)C(=O)c1nc(C(=O)OC(C)(C)C)cs1 +Cc1ccc(NC(=O)c2c(C)oc3ncn(CC(C)C)c(=O)c23)cc1 +O=c1ccc(-n2cncn2)nn1Cc1ccccc1F +COc1ccccc1OCCSc1nc(C)nc(C)c1C(C)=O +CCCN(CCC)C(=O)NCc1cccc(C#N)c1 +CS(=O)(=O)NCCC(=O)Nc1ccn(Cc2ccccc2)n1 +Cc1nnsc1C(=O)N1CCC(Cn2cccn2)CC1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NC(C)c1cnn(C)c1)O2 +O=C1Cc2cc(NC(=O)c3ccccc3Cl)ccc2N1 +Cc1ccc(C(=O)OC(C)C)c(S(N)(=O)=O)c1 +CN(C)C(=O)COc1cccc(CNC(=O)NC2CCCC2)c1 +Cc1cc(C(=O)Nc2ccc(-n3nc(C)cc3C)c(F)c2)on1 +CN(CC(=O)Nc1ccc(F)cc1)C(=O)c1n[nH]c2ccccc12 +CCc1onc(C)c1NC(=O)CCn1c(C)c(C)sc1=O +Cc1nc(CCSc2nnnn2-c2ccc(O)cc2)cs1 +Cc1ccc2c(c1)N(CC(=O)NCCO)C(=O)C(C(C)C)O2 +Cc1c(NCc2nnc(C3CC3)o2)cccc1N1CCOC1=O +Cc1ccc(C(=O)OCC(=O)NCC(=O)NC(C)C)cc1O +CN1CCN(C(=O)Cc2cccc(OCC#N)c2)c2ccc(F)cc21 +Cc1nc2ncnn2c(C)c1CCC(=O)N1CC(C(N)=O)CCC1C +CCN1CCN(C(=O)C(C)N2CCN(C(C)=O)CC2)CC1 +CC(NC(=O)c1ccoc1)C(=O)Nc1ccc(OC(F)F)c(F)c1 +CCOc1cc(C)ccc1NC(=O)C(C)NC(=O)c1ccoc1 +O=C(c1cc[nH]n1)N1CCOC2(CCCN(c3cnccn3)C2)C1 +CC(C)Oc1ccc(S(=O)(=O)N2CCCCC2CCO)cc1 +CC(=O)Nc1cccc(C(C)OC(=O)C2CC(=O)N(CC3CC3)C2)c1 +Cc1ccc2c(c1)CCCN2C(=O)Cn1c(C)csc1=O +COCCNC(=O)c1ccccc1NC(=O)c1cccc(N(C)C)c1 +Cc1ccccc1C1CCN(S(=O)(=O)N(C)C2CCOCC2)C1 +CCOc1ccc(-c2nnc(SC(C)C(=O)NC3CC3)n2N)cc1 +COCc1ccc(C(=O)NCc2c(F)cccc2Cl)o1 +COc1ccc(C(=O)NCCCC(C)C)cc1OC +CCCNC(=O)CNC(=O)c1cnn(C)c1-n1cccc1 +Cc1ccc(-c2cc(C(=O)NCCSc3nnnn3C)[nH]n2)s1 +CCn1c(=O)c2ccccc2n2c(CNc3ccc(C)c(C)c3)nnc12 +c1ccc(CNc2nc3nonc3nc2N2CCOCC2)cc1 +COCc1ccccc1C(=O)OCc1ccc2nn[nH]c2c1 +CC(CNc1ccc(C(N)=O)cc1)c1ccccc1 +COc1ccc(-n2ccc(C(=O)NCc3nc(C)c(C)o3)n2)cc1 +Cc1ccc(-c2nc(CCN(C)C(=O)NC(C)C)no2)cc1 +CC(=O)Nc1ccc(NC(=O)COc2ccccc2O)cc1 +CC(NC(=O)NCCc1nccn1Cc1ccccc1)c1ccncc1 +Cn1cc(C(=O)OC(C(=O)c2ccccc2)c2ccccc2)cn1 +Cc1nc2ccc(NC(=O)c3cnn(C(C)(C)C)c3)cc2o1 +Cc1cccc(CNC(=O)COC(=O)c2ccc3ccccc3n2)c1 +COCCN1CCN(Cc2nnc(-c3ccc(C#N)cc3)o2)CC1=O +Cc1ccc(Cl)c(OCCN2CCOCC2)c1C +Nc1ncccc1C(=O)N1CCN(C(=O)c2ccco2)CC1 +CCOc1ccc(S(=O)(=O)N(C)Cc2c(C)noc2C)cc1 +CN(C)C(=O)CN1c2cccc3cccc(c23)S1(=O)=O +COc1nc(N(C)C)n(C)c(=O)c1C1CCCCC1 +COC1CCC(OC(=O)C(C)N2CCc3ccccc3C2)CC1 +Cc1nc2c(c(C)c1CC(=O)Nc1ccccc1O)c(=O)[nH]n2C +CCC(CC(=O)Nc1cc(C(N)=O)n(C)c1)c1ccccc1 +CC(=O)Nc1ccc(NC(=O)Nc2cc(F)cc(F)c2)cc1 +N#CC(OC(=O)c1ccc(-n2ccnc2)cc1)C1CCOC1 +CC(C)(C)CCNC(=O)c1c[nH]c2ccccc2c1=O +CC(Cc1ccccc1Cl)NC(=O)Nc1ccncc1 +CCCNC(=O)N(C)Cc1c(C)nn(-c2ccccc2)c1C +COc1ccc(N2CCn3c2nn(C)c(=O)c3=O)cc1 +CCc1ccsc1C(=O)NC(c1noc(C)n1)c1ccccc1F +Cc1cccc(N(C)C(=O)c2cc3c(C)nn(C)c3s2)c1 +COC(C)(C)c1noc(-c2cc(-c3ccccc3)on2)n1 +O=C(CNC(=O)c1cccnc1OCC(F)F)Nc1ccccn1 +Nc1cccc(C(O)CNc2cc(Cl)ccc2Cl)c1 +CN(CCNC(=O)Cn1nc2ccccc2n1)S(C)(=O)=O +O=C(NCCc1n[nH]c(-c2ccco2)n1)c1c[nH]c2cccc(F)c12 +Cc1cccc(NC(=O)COc2ncnc3oc(C)c(C)c23)c1 +CCc1csc(CCNc2ccc(-c3nc(C4CC4)no3)cn2)n1 +CC1CN(C(=O)c2cccc(N3CCCS3(=O)=O)c2)C(C)CO1 +c1cnc(NCc2ccc(Cn3cnc4ccccc43)cc2)nc1 +CC(NC(=O)CCCCc1nc2ccccc2s1)C1CCCO1 +CC(C)OCCCNC(=O)Cn1ccc2ccc(Cl)cc21 +CCOC(=O)CN(C)C(=O)c1c[nH]c2cccc(F)c12 +O=C(CN1C(=O)COc2ccccc21)Nc1ccc2cc[nH]c2c1 +CCN(CC)C(=O)Nc1cccc(COCC2CC2)c1 +O=C(Nc1ccccc1OC(F)(F)F)c1cn[nH]n1 +N#CCCCN1C(=O)CNc2cc(F)c(F)cc21 +CS(=O)(=O)NCc1ccc(OCc2ccccc2)cc1 +Cc1ccc(C(=O)N(C)C)cc1NC(C)C1(C)CC1 +COc1cc2nc(-c3cncnc3)nc(N)c2cc1OC +CCOc1ccc2cc(C(=O)N3CCC(OC)CC3)[nH]c2c1 +Cc1nn(C)c(C)c1CC(C)NC(=O)NCC1CN2CCCC2CO1 +O=C(c1ccco1)N1CCn2cccc2C1c1ccc(F)cc1 +COCCCNC(=O)Nc1ccc2nc(C)sc2c1 +Cc1noc(C)c1CCNC(=O)N1CCOCC1C1CC1 +CCc1cc(NC(=O)c2ccc(OCC(F)F)nc2)n(C)n1 +CC(=O)Nc1ccc(NC(=O)c2csc(C)n2)cc1Cl +CCN(CC)C(=O)c1cc(S(=O)(=O)NC)ccc1Cl +COCC(C)OC(=O)c1ccc(Cn2cccn2)cc1 +Cc1cc(C(=O)OCCCn2nc3ccccn3c2=O)c(C)s1 +CC(C)Cc1cc(C(=O)NC(C)c2ccc(-n3cncn3)cc2)on1 +CC(=O)Nc1ccc(NC(C)c2ccc(F)cc2)cc1 +COc1cccc(CC2(c3ccco3)NC(N)=NC2=O)c1OC +COC(=O)c1c(C)[nH]c(C(=O)CN2CCCc3ccccc32)c1C +CCCN(Cc1ccc(C#N)cc1)C(=O)C(C)NC(C)=O +O=C(Nc1cccc(-c2nnco2)c1)c1ccnc(OC2CCC2)c1 +CC(=O)NCCCc1ncnn1Cc1cccc(C)c1 +Cn1ncc(NC(=O)Cn2cc(-c3ncccn3)cn2)n1 +C=CCNc1cccc(CS(=O)(=O)c2ccccc2)c1 +CCCn1cc(C(=O)N(C)Cc2sccc2C)c(C)n1 +O=C(CC1CN(Cc2ccccc2)CCO1)Nc1nncs1 +Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccnc3)c2)c1 +Cc1nn(C)c(C)c1CC(=O)Oc1ccc(Br)cc1F +Cc1ccc(NC(=O)c2cc(C(N)=O)cs2)cc1C +CC(C)COCCC(=O)Nc1cc(Cl)ccc1N +CC(NC(=O)NC(C)C1CCCO1)c1ccc(OC(F)(F)F)cc1 +Cc1cccc(C2CCCCCN2C(=O)Cc2cnn(C)c2)c1 +Brc1cnc(-c2cccs2)nc1C1CC1 +Cc1c(C)c(C)c(S(=O)(=O)N2Cc3cncnc3C2)c(C)c1C +O=C(Nc1ccccc1Cn1cccn1)c1cccc(Cl)c1 +COCCNC(=O)NCCc1nnc(-c2ccccc2)o1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)NCCC(C)C +Cc1cc(C)cc(Nc2ncnc(N3CCCC3)c2N)c1 +CCCNC(=O)c1ccc2c(c1)S(=O)(=O)c1ccccc1C2=O +CCOC(=O)c1csc(CNC(=O)c2ccccc2OC)n1 +Cc1ccc(S(=O)(=O)CC(=O)NC2CCOc3ccccc32)cc1 +COc1cccc(OCC(=O)NCc2ccccc2C)c1 +Cc1nc(-c2ccc(CNc3ccc4nnnn4n3)s2)cs1 +CCc1cnc(C)nc1NCCSc1nnc(C)n1CC +COCCNC(=O)c1cccc(S(=O)(=O)N2CCC(C)CC2)c1 +Cc1ccc2c(c1)c(=O)c(C(=O)Nc1cnn(C)c1)nn2C +O=C(NCC1(N2CCOCC2)CCCCC1)c1n[nH]c2ccccc12 +CC(Oc1ccc(F)c(F)c1)C(=O)n1ccnc1 +COc1ccc(-c2nc(-c3ccc4nncn4c3)no2)cc1OC +O=C(NCc1ccnc(OCC2CC2)c1)NCC(F)(F)F +Cc1cc(C)c2nc(NC(=O)c3ccc(S(C)=O)cc3)sc2c1 +C=CCN(CC=C)C(=O)NCc1cn(-c2ccccc2)nn1 +COc1cccc(CNC(=O)CCn2c(=O)oc3ccccc32)c1 +COc1ccc(CC(=O)N2CCCC(N3CCNC3=O)C2)cc1OC +Cc1ccc(CNC(=O)c2ccc(NS(C)(=O)=O)cc2)cc1 +CN(Cc1ccccc1)S(=O)(=O)c1cccc(F)c1 +CN1CC(=O)N2CCN(C(=O)c3cc(N)ccn3)CC2C1=O +CCn1cc(C#N)c(=O)n(Cc2nc3ccsc3c(=O)[nH]2)c1=O +COc1ccc2cc(C(=O)NC(C)c3ccncc3)c(C)nc2c1 +N#CC(CCC(=O)NCc1cccnc1)c1cccnc1 +Cc1csc(N2CCN(CCC(=O)OC(C)(C)C)CC2)n1 +CCCc1cc(C(=O)N2CCc3sc(C(N)=O)cc3C2)[nH]n1 +CCCc1nnc(NC(=O)Cc2coc3ccc(OC)cc23)s1 +Cc1cccc(OCc2nnc(SC3CC(C)OC3=O)o2)c1 +CCCN(Cc1ccc(C#N)cc1)S(=O)(=O)c1ccccc1F +NC(=O)c1nc(CC(=O)NCc2ccccc2)no1 +N#Cc1cccc(C(=O)N(Cc2ccccn2)C2CC2)c1 +COc1c(NC(=O)Cc2c[nH]c3c(C)cccc23)c(C)nn1C +Cc1ccc(CN(C)C(=O)Nc2ccc3c(c2)COC3)s1 +Cc1ccc(CCNC(=O)COc2ccc(F)cc2F)o1 +O=C1COc2cc(C(=O)NCC(F)(F)F)ccc2N1 +CCCCC(=O)N1CCC(NC(=O)c2ccccc2C)CC1 +Cc1cc(C)nc(N2CCCC2c2cc(C)on2)n1 +CC(C)CCN(C)C(=O)C1CCN(C(=O)N2CCCC2)CC1 +O=c1c2ccsc2nc2n1CCN(Cc1ccc(F)c(F)c1)CC2 +COc1ccc2c(c1OC)CCNC2c1ccncc1F +CC(=O)c1cccc(NC(=O)C(N)c2ccccc2)c1 +CC(=O)Nc1ccc(NC(=O)NC(C)C(C)CO)cc1 +CC1(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)CCCO1 +Cn1ccc(NC(=O)c2ccc3c(c2)OCCCO3)n1 +Cc1nccn1-c1ccc(NC(=O)C(C)(C)C)cn1 +CCc1cccc(CC)c1NC(=O)CS(=O)(=O)c1ccc(O)cc1 +COCCN(CC(C)C)C(=O)c1cc(F)c(F)c(F)c1 +Cc1ccc(CC(=O)N2CCN(C(=O)C(C)NC(N)=O)CC2)cc1 +CCOc1ccc(NC(=O)CNC(=O)OC)cc1Cl +CC(C)n1cnnc1SCc1noc(C2CC2)n1 +NC(=O)c1cnn2c1NCC=C2c1cccc(C(F)(F)F)c1 +CCC(=O)N1CCN(c2cc(Oc3ccccc3Cl)ncn2)CC1 +O=C(CC1OC(=O)c2ccccc21)NCC(=O)NC1CC1 +CC(=O)Nc1ccc2c(c1)Cc1c(F)ccc(F)c1-2 +CCN(CC(=O)NC(C)C)C(=O)c1ccc(C(=O)NC(C)(C)C)cc1 +C#CCNC(=O)NCCCCN(C)c1ccccc1 +COCCNC(=O)CCNc1cnc2ccccc2n1 +Cc1cccc2c1C(NC(=O)CCc1c(C)nn(C)c1C)C(=O)N2 +CN(C)C(=O)c1ccc(Cl)c(NC(=O)Cn2cnnn2)c1 +COC(=O)COc1cccc(NC(=O)c2cc(C)c(C)s2)c1 +Cc1cc(NC(=O)c2nc3nc(C)cc(C)n3n2)[nH]n1 +O=C(c1cc(Br)ccc1F)C1CCC1 +c1nc(N2CCCCC2)sc1CN1CCOCC1 +COC(=O)CSc1nc2[nH]c(C)c(C)c(=O)n2n1 +Cc1ccc(C(=O)CSc2nc(C)cc(=O)[nH]2)cc1 +COc1ccnc(NCCC(=O)N2CCN(c3ncccn3)CC2)n1 +Cc1csc(C(C)NC(=O)Nc2c(C)cccc2OC(F)F)n1 +COCCN(CCOC)C(=O)c1cc(Cl)cc(Cl)c1 +CC(=O)Nc1ccc(F)c(NC(=O)c2ccccc2OCC(N)=O)c1 +COc1ccc(-c2cc3nc4n(c(=O)c3s2)CCC4)cc1 +CCCNC(=O)CNC(=O)NCCc1nc2ccccc2s1 +NC(=O)COC(=O)C1CC1c1ccccc1Cl +Cc1noc(C)c1C(C)NC(=O)Nc1ccc(NC(=O)C2CC2)cc1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2cccc(Br)c2)c1C +CC(c1ccccc1Cl)n1cnc2c1c(=O)n(C)c(=O)n2C +CCOc1cc(C(=O)NCc2cccs2)ccc1OC +NC(=O)c1nc(-c2cccnc2)nc2c1[nH]c(=O)n2Cc1ccccc1 +CCC(C(=O)NCC1CCC(C)(C)CC1)N1CCCC1=O +COCCN1CCN(C(=O)Nc2ccc(Cl)cc2F)CC1=O +Cc1cc(N)ccc1NC(=O)CC1CC2CCC1C2 +Cc1ccc(C(C)NC(=O)NCCCNC(=O)C2CCC2)cc1F +Cc1ccc(F)c(NC(=O)CCn2nc(-c3cccs3)oc2=O)c1 +CCCNC(=O)c1nnn(-c2cccc(C)c2)c1COC +Cc1cc(C)n2nc(C(=O)NCCCc3nc4ccccc4[nH]3)cc2n1 +CS(=O)c1ccc(C(=O)OC2CCCC2)cc1 +CCOC1CN(C(=O)c2cc(C)on2)C2COCC12 +CC(C)Cc1cc(C(=O)NCC2(C(N)=O)CCOCC2)[nH]n1 +CCCNC(=O)c1cccc(C(=O)NCc2cccc(F)c2)c1 +CCOc1ccc(NC(=O)N2CCCC(c3cc[nH]n3)C2)cc1C#N +O=C(NC1CCCOC1)c1cnn(-c2ccc(F)cc2)c1 +CCn1ncc(C(=O)Nc2cc(C#N)ccc2Cl)c1C(F)(F)F +CCOc1ccc(NC(=O)C2CCC2)cc1Cl +C=CCCCN(C)C(=O)c1ccc(=O)n(Cc2ccccc2)n1 +O=C(NCc1ccc(F)c(Cl)c1)C1CC2CCC1O2 +CCN(CC(=O)N(C)Cc1ccccc1)CC(C)C#N +O=C(COc1cc(Cl)ccc1Cl)NCCCN1CCCC1=O +CCC(C)n1nccc1NC(=O)C(C)NCc1nnc2n1CCCC2 +Cc1cc(O)ccc1NC(=O)c1ccc(NC(=O)C2CC2)cc1 +CC1=C(C(=O)OC(C)C)C(c2c(F)cccc2Cl)NC(=O)N1 +Cc1occc1C(=O)NCc1ccc(OC(C)C)cc1 +CCCC(O)c1ccc2c(c1)C(NC(=O)C(C)C)CCC2 +CCn1nnc(NC(=O)c2ccc(C)c(Cl)c2)n1 +CCN(CC)C(=O)c1ccc(-c2ccccc2)nc1N +COc1cccc2c1C(c1ccc3c(c1)OCCO3)NCC2 +CCCn1nnnc1NC(=O)c1ccc(C)cc1Cl +CC(C)=C1C(=O)N(C)c2ccc(S(=O)(=O)N3CCCCC3)cc21 +O=C(CCNC(=O)c1ccco1)Nc1ccnn1C1CCCC1 +COc1ccc(OC)c(CN(C(=O)c2cccc(C)c2)C2CC2)c1 +O=C(NCc1cscn1)c1cn2cccnc2n1 +Cc1ccc(-n2nc(C)c3c2CC(C)(C)CC3=O)cc1 +CCNC(=O)CCCOc1ccc(Cl)c(C)c1 +CSc1cccc(NC(=O)N2CCC(C)CC2)c1 +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)NCCC1=CCCCC1 +Cc1cc(NC(=O)c2ccc(C(=O)N(C)C)cc2)[nH]n1 +CS(=O)(=O)c1ccc(NC(=O)CCOCc2ccccc2)cc1 +COCC1CCCC12CN(Cc1c(C)noc1C)CCO2 +CCn1cc(CNC(=O)c2sc3ccccc3c2Cl)c(C)n1 +COc1ccc(Br)cc1NCCN1CCOCC1 +Cn1c(C(=O)NCc2ccco2)cc2c(=O)n3ccccc3nc21 +O=C(Nc1cccn(Cc2ccc(F)cc2)c1=O)c1cccs1 +Cn1ncc2c(N3CCC(CC(=O)NC4CCCC4)CC3)ncnc21 +CCc1ncc(CNC2(c3ccc(F)cc3)CCOCC2)s1 +CCc1nnc(C(=O)Nc2cccc(C(=O)NC(C)CC)c2)s1 +Nc1cccc(-c2nc3ccccn3c2CN2CCOCC2)c1 +CC(Cn1cncn1)NC(=O)Cc1cccc(OCC#N)c1 +Cc1cc(Oc2ccccc2)nc(C2CCN(C(=O)c3cc[nH]n3)C2)n1 +Cc1occc1-c1nnc(SC(C)C(=O)Nc2ccc(F)cc2)o1 +NC(=O)c1ccccc1OCC(=O)NCC1Cc2ccccc2O1 +Cc1cc(C(=O)N2CCCCC2C)ccc1NC(=O)N(C)CC1CC1 +Cn1ccnc1SCc1nc(-c2ccc3c(c2)OCO3)no1 +COc1cc(-c2ccc(CO)cc2)ccc1NC(C)=O +Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccc3c(c2)OCO3)n1 +Cc1cccc(NC(=O)CCNS(=O)(=O)c2ccc(F)cc2)n1 +OC(c1ccc(OC(F)F)c(OC(F)F)c1)C1CCOCC1 +CN(CCC1(O)CCCC1)C(=O)C(c1ccc(F)cc1)N(C)C +O=C(c1ccc(F)cc1F)N1CC(c2nc(-c3ccco3)no2)C1 +Cc1c(C(=O)N2CCCC(CO)C2)oc2c(C)cccc12 +COC(=O)N1CCC(NC(=O)C(C)Sc2ccccc2)CC1 +Cc1noc(C)c1CN(C)C(=O)c1cn2ccsc2n1 +O=C(NCCC(O)C1CC1)C12CC3CC(CC(C3)C1)C2 +CC(C)CCNS(=O)(=O)c1ccccc1C#N +NC(=O)C1CCN(C(=O)c2csc(-n3cccc3)n2)CC1 +CC(=O)c1oc2ccc(Br)cc2c1N +CC(C)S(=O)(=O)c1ccc(C(=O)c2nccn2C)cc1 +Cn1cnc(S(=O)(=O)N2CCC3(C=Cc4ccccc43)CC2)c1 +CCc1c(C)sc2ncn3nc(-c4ccncc4)nc3c12 +CN(C)C(=O)c1ccccc1NC(=O)CC(C)(C)C +CNC(=O)CCc1ccccc1NC(=O)NC1Cc2ccccc2C1 +CC(=O)c1cc(-c2ncc(C(F)(F)F)cc2Cl)no1 +O=c1onc(-c2cccnc2)n1CCCc1ccc(Cl)cc1 +CCCn1nc(C(=O)NCC(C)c2cccs2)ccc1=O +CCNc1cccc(C(=O)NCc2csc(C)n2)n1 +CCN(CCO)C(=O)COc1ccc2oc3c(c2c1)CCCC3 +CC1(C)CC2CC(C)(CN2c2cncc(C#N)n2)C1 +CCC1=C(C(=O)OC)C(c2ccccn2)NC(=O)N1C(C)C +CNc1nnc(SCC(=O)Nc2nc(OC)cc(OC)n2)s1 +Cc1cc(=O)c(C2NCCc3ccc(Cl)c(F)c32)c[nH]1 +COCc1cc(C(=O)NCc2cccc(C(F)(F)F)c2)ccc1F +CC(=O)C1(c2ccccc2)CCN(C(=O)c2cnn(C(C)C)c2)CC1 +Cc1cccc(Cn2cccc(C(=O)Nc3nnc(C)s3)c2=O)c1 +Cc1c(C(=O)OCc2nnc(C)n2C2CC2)cnn1-c1ccccc1 +Cc1nnc(NC(=O)Nc2cccc3ccccc23)nc1C +COCCN1C(=O)NC(c2ccccc2)C(C(=O)OC)=C1C +Cc1cc(C)c(C(=O)NCC2CC23CCc2ccccc23)c(=O)[nH]1 +CCOC(=O)CSc1ccc(-c2nc(C)no2)cn1 +COc1ccc(C)cc1NC(=O)Nc1cccc(C(C)=O)c1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)C1CCC(F)(F)CC1 +Cc1cccc(NC(=O)CSc2nnnn2C)c1 +CC(=O)NCc1ccc(OC(C)=O)c(OC(C)=O)c1 +c1csc(-c2noc(COCC3CCCO3)n2)c1 +CCOc1ccccc1CNC(=O)NCCc1cccnc1 +CCCN(Cc1cnn(-c2ccc(F)cc2)c1)CC(F)F +CC(C)C(=O)N1CCC(COc2ccccc2)CC1 +O=S(=O)(Cc1ccccc1Cl)NCc1ccccn1 +CC1CCCCC1N(C)C(=O)c1c(O)cc(F)cc1F +CCn1c(C)cc(C(=O)Nc2cc3c(cc2Cl)OCCO3)c1C +CCc1cccc(CC)c1NC(=O)NCCCC(N)=O +Cc1cc(NC(=O)c2cccc(NC(=O)c3cccs3)c2)ccn1 +Cc1cnc(S(=O)CC(=O)NCc2sccc2C)nc1 +COc1cc(C)ccc1OCC(=O)N1CCC(=O)Nc2ccccc21 +CCNC(=O)c1ccc(NCC(=O)Nc2cc(C)nn2C)c(C)c1 +CCOc1ccccc1NC(=O)CCC(=O)c1ccc(F)c(F)c1 +Oc1ccc(NCc2nnc3n2CCCCC3)cc1 +COc1cccc(OC)c1-c1ccc2c(c1)NC(=O)CO2 +Cc1c(S(=O)(=O)N(C)C)cnn1-c1ccccc1Cl +CC(=O)N1CCCCC1CC(=O)N1CCCCC1c1nc(C)cs1 +Cc1cc(C)cc(OCCC(=O)N2CCOCC2)c1 +COc1ccccc1OCC(=O)N(C)c1ccc(C)cc1C +Cc1noc(C)c1CCCNC(=O)Nc1ccc(F)c(C#N)c1 +COCc1ccccc1NC(=O)NCC1(O)CCCc2ccccc21 +Cc1ncc(CNC(=O)c2ccccc2OCc2cscn2)s1 +CCC1(C(=O)N2CCC(OCc3ccccc3C)CC2)CCC1 +CNC(=O)Cn1c(CO)cnc1SCc1ccc(Cl)cc1 +COc1cccc(C(O)CCN2CCOCC2)c1 +O=C(CCN1CCOCC1)c1ccc(OCc2ccccc2)cc1 +CCc1nnc2ccc(-c3noc(COc4ccccc4)n3)cn12 +c1ccc(CCNc2ncnc3c2cnn3-c2ccccn2)cc1 +FC(F)(F)c1ccc(N2CCOCC2C2CC2)nn1 +CC(=O)Nc1cccc(NC(=O)COc2cccc3cccnc23)c1 +Cc1ccc(CNC(=O)c2ccc(Cn3cncn3)cc2)cc1 +Cc1cc(NC(=O)Cc2ccc(F)cc2F)ccc1C(N)=O +CCCC(=O)N1CCCC(C(=O)NCC(=O)OC)C1 +Cc1cc(NC(=O)CSc2nnc(-c3ccc(O)cc3)o2)no1 +CCCCNC(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +Cc1occc1CNC(=O)N(CCO)C1CCCc2ccccc21 +Nc1ccc(C(=O)N2CCCc3ccccc32)cn1 +Cc1cc2nccc(-c3cnc4sccn4c3=O)n2n1 +CS(=O)(=O)N1CCCC(C(=O)NCCc2cc(F)cc(F)c2)C1 +CCc1noc(C)c1C(=O)Nc1ccc(-n2nc(C)cc2C)c(F)c1 +CC(C)OC1CN(C(=O)CCCc2ccc(Cl)cc2)CC1O +COc1cccc(CNS(=O)(=O)c2cccc(Cl)c2)c1OC +CCN(CC)C(=O)NCc1cn(-c2ccc(OC)cc2)nn1 +O=C(Cc1cccc(F)c1)N1CCC(c2n[nH]c3nccnc23)CC1 +COc1ccc(-c2n[nH]c(C3CC3)c2NC(=O)C2CC2)cc1OC +Cc1c(-c2ccccc2)sc2nc(-c3cnccn3)[nH]c(=O)c12 +C=CCn1c(SCc2ccncc2)nnc1C(F)(F)F +COCC(=O)N1CCC2(CCCN(c3ncc(F)cn3)C2)C1 +CNc1cc(N(C)S(=O)(=O)c2cccs2)ccc1C +CCOC(=O)CN(C(=O)c1ccccc1F)C(C)C +CC(CO)NC(=O)NCCOc1ccc2c(c1)OCO2 +Cc1ccc2ncc(C(=O)NC(C)c3ccc(NC(N)=O)cc3)n2c1 +Cc1cc(S(N)(=O)=O)c(F)cc1Br +COCC(=O)N1CCCC2(CCN(Cc3ccc(OC)cc3)C2=O)C1 +Cc1nc(C(C)(C)NC(=O)c2cscn2)sc1C +COc1cc(CN(C(=O)Nc2nncs2)C2CC2)ccc1O +Cc1ccccc1NCCC(=O)NCc1cnn(C)c1 +Cc1c(C(=O)N2CCC(CO)CC2)sc2cccc(F)c12 +Brc1ccc2nc(NCCN3CCOCC3)sc2c1 +CC1CN(Cc2ccc(C(=O)NCc3ccccc3F)cc2)CCO1 +O=C(NC1CCOCC1)c1cccc(-n2cnnc2)c1 +CC1CN(C(C)(C)CNC(=O)C(C)NC(=O)C(C)(C)C)CC(C)O1 +COCc1ccccc1NC(=O)NCc1nnc2ccccn12 +O=C(Nc1ccc2nc(C3CC3)oc2c1)N1CCOCC1C1CC1 +Cc1cc(C)n(CC(=O)Nc2ccc3cn[nH]c3c2)n1 +CNC(=O)c1cncc(OC2CC2)c1S(N)(=O)=O +CCC(NC(=O)c1c[nH]c2cccc(F)c12)c1c(C)nn(C)c1C +CCn1ccc2cccc(Br)c2c1=O +O=S(=O)(Cc1ccccn1)c1ccc(Cl)c(C(F)(F)F)c1 +CCOC(=O)c1cccc(NC(=O)Cc2ccc(OC)cc2)c1 +Cn1c(=O)sc2cc(S(=O)(=O)N3CCCCC3)ccc21 +COc1nc2ccccc2nc1N1CCN(Cc2ccccc2)CC1 +Cc1cc(C(=O)NC2CC3CC2C2CCCC32)c(C)o1 +COc1ccccc1CN(C)C(=O)c1cc(C2CC2)nc2ccccc12 +Cc1cccc2c(CC(=O)Nc3ccc(N(C)C)nc3)c[nH]c12 +Cc1cccc(NC(=O)C(Cc2ccccc2)NC(N)=O)c1 +O=C(NCc1ccco1)c1nn(-c2ccccc2)c(=O)c2ccccc12 +CN1CCOC(CCNC(=O)c2cnc(-c3ccccn3)nc2)C1 +COC(=O)C1CCN(C(=O)NC2CCCC2)CC1 +CCCOc1cc(C)ccc1NCc1noc(C2CC2)n1 +Brc1cccc(-c2ncn3c2COCC3)c1 +COC(=O)CN(C)C(=O)CCc1ccc(C)c(Cl)c1 +O=C(NC1CCCCNC1=O)c1ccc(-c2ccco2)[nH]c1=O +O=C1CSc2ccc(C(=O)NCc3ccccc3)cc2N1 +CCc1cc(-n2ccnc2-c2cccnc2)ccc1NC(C)=O +O=C(c1cccc(F)c1F)N1CCN(C2CCCC2O)CC1 +CCCN1Cc2cccc(C(=O)Nc3ccc(F)c(Cl)c3)c2C1=O +Cc1ccc(CNC(=O)Cn2nnc3ccccc3c2=O)cc1 +Cc1cc(N2CCOC(Cc3ccccc3)C2)ncn1 +CC(=O)Nc1ccc(C(=O)NC2CCc3c(Cl)cccc32)cc1 +O=C(Nc1cccc(OCC2CCCO2)c1)C1CCC1 +Cc1ccccc1OCCN(C)C(=O)c1cc(Cl)ccn1 +CCN(CCC#N)C(=O)CNc1ccc(-n2cncn2)cc1 +Cc1ccc2[nH]nc(C(=O)OCCNc3cccnn3)c2c1 +COc1ccc(COC2OC(CO)C(O)C(O)C2NC(C)=O)cc1 +CCOc1ccccc1C(=O)Nc1nc(C)cc(C)n1 +CC(OC(=O)CCCc1nc2ccccc2c(=O)[nH]1)C(N)=O +CCc1cccc(NCc2ccc(C(N)=O)cc2F)c1 +C=CCNc1nc(SC)ncc1C(=O)OCC +COCC(=O)Nc1ccc2c(c1)CCC(=O)N2CCC(C)C +CCC1CCCCN1C(=O)Cc1c(C)nc(-c2ccncc2)[nH]c1=O +Nc1cn(Cc2ccccc2)c(=O)n(Cc2ccccc2)c1=O +C=CCN1C(=O)c2ccccc2NC12C(=O)Nc1cc(O)ccc12 +CCOC(=O)CC(C)CNC(=O)c1cccc(C)c1C +CC(C)c1ccc(CNC(=O)CSc2ncccc2C#N)cc1 +CCC(NC(=O)c1cn(C)nc1C(C)(C)C)c1nc(C)cs1 +COC(=O)C(C)(C)NC(=O)c1ccc(-n2cncn2)nc1 +Cc1c(C(=O)CC2OC(=O)c3ccccc32)cnn1C +O=C(c1ccccn1)N1CCC(n2cnc3cccnc32)CC1 +O=C(N1CCOCC1)N1CCc2[nH]nc(-c3c(F)cccc3F)c2C1 +Cc1ccc(Nc2ncnc(NCC3CCCO3)c2N)c(C)c1 +COc1ccc(NC(=O)c2ccc3c4c(cccc24)CC3)cn1 +CCCCC(=O)NCCn1ccc(-c2ccncc2)n1 +O=C(c1cccnc1)N1CCN(CCCOCC(F)(F)F)CC1 +NS(=O)(=O)c1cc2c(=O)oc(=O)[nH]c2cc1Cl +Cc1ccnc2nc(C(=O)OCC3CC=CCC3)nn12 +CC(C)NC(=O)NCc1cccc(COc2ccccc2)c1 +O=C(NCc1cccs1)NC1CCN(c2ccccc2)C1=O +CCC(C)NC(=O)Nc1ccc(C)c(-n2cnnn2)c1 +COc1ccc(C(=O)NCC(C)(C)N2CC(C)OC(C)C2)c(F)c1 +CCc1nnsc1C(=O)N1CCCC(c2noc(C)n2)C1 +O=C(Oc1cccc(-c2nnco2)c1)N1CCOCC1 +FC(F)(F)c1cccnc1NCCc1ccncc1 +Cn1cc(-c2cnc3ccc(NCc4ccc(C#N)cc4)cc3c2)cn1 +O=C(Nc1nnc(-c2cccs2)o1)C1CCCCC1 +N#Cc1ccccc1NC(=O)c1ccn(-c2ccccc2)n1 +CC(c1ccccc1F)N(C)C(=O)C1CC(=O)Nc2ccccc21 +CC(C)(C)OC(=O)N1CCCC1Cn1nnnc1NC1CC1 +Cn1nc(NCCc2cccs2)c(=O)n(C)c1=O +CCOC(=O)c1sc(NC(=O)c2ccncc2)c(C(=O)OC)c1C +O=C(c1ccc2cc[nH]c2c1)N1CCC(Nc2ccccc2)C1 +Cc1noc(C)c1CNC(=O)C1CC(=O)N(C(C)c2ccccc2)C1 +COC(=O)c1cc(CNC(=O)NCc2cccc(F)c2)oc1C +CCOC1c2cc3cc(OC)ccc3nc2Sc2nccn21 +Cc1nc(C(N)c2ccccc2Cl)n(-c2cccc3cccnc23)n1 +COc1ccc(NC(=O)C(C)Sc2cc(C)ncn2)cc1OC +CCC(OC)C(=O)N(C)Cc1ccc(C(=O)NC)cc1 +CC(C)c1ccccc1NC(=O)N(C)Cc1nccn1C(F)F +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(OC(F)F)cc1 +O=C(COc1cccc2c1CCCC2)N(CCO)CCO +COCc1nc(C(=O)OCCc2cccnc2)cs1 +Cc1ccccc1-n1c(C)nnc1SCC(=O)NC(C)C +CCC(C)C(NC(=O)c1cc(C)n(CC)c1C)C(N)=O +CC(Sc1nncn1C(C)C)c1ccc(F)cc1F +N#Cc1ccc(C(=O)Nc2cc(F)ccc2Cl)cc1 +CC(C)Cn1cc(N2CC(C(=O)NCC3CC3)CC2=O)cn1 +O=C(COc1ccc(F)cc1)Nc1cccc(CO)c1 +O=c1c(C(F)(F)F)cc(C2CC2)nn1Cc1ccno1 +CC1(CNC(=O)C2CCCN2C(=O)Cc2ccccc2)CCCO1 +Cc1ccccc1OCCCN(C)C(=O)C(C)NC(N)=O +CCOC(=O)c1scc(S(=O)(=O)c2ccc(Cl)cc2)c1N +Cc1csc(SCc2cc3c(cc2N)OCCO3)n1 +CC(C)CNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1 +Cc1noc(C(C)OC(=O)COc2ccc3ccc(=O)oc3c2)n1 +N#Cc1ccc(CNC(=O)c2cc(Cl)ccc2-n2cnnn2)cc1 +CC(C)(C)c1nnc(CNc2cccc(Oc3ccc(C#N)cn3)c2)o1 +CC(C)c1nnc2sc(-c3ccc(-n4cccn4)cc3)nn12 +N#Cc1ccc(OC2CCC(NC(=O)c3cnns3)CC2)nc1 +Cc1cc(CN(C)C(=O)c2c(F)cccc2F)no1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NCc1ccoc1 +COc1ccc(-c2cn3cc(N)cc(OC)c3n2)cc1C +CCN(CC)C(=O)NCC(O)c1ccccc1C +C=CCn1c(=O)n(-c2ccccc2)c(=O)c2cc(OC)c(OC)cc21 +O=C(NCc1ccc(Cl)c(Cl)c1)c1cc2cccn2cn1 +CCOC(=O)c1c(C)nc(N2CCOCC2)nc1C(F)(F)F +Cc1ccc(C(=O)N2CCCCCC2c2ccco2)c(C)n1 +O=C(Nc1ccc2oc(-c3ccncc3)nc2c1)c1ccc(F)cc1 +Cc1cc(C(N)C(=O)NCC2CCCO2)ccc1O +Cc1c(Cl)cccc1NC(=O)c1cn2c3c(cccc3c1=O)CC2 +Cn1cc(C(=O)OCC(=O)C2CC2)c(-c2cccs2)n1 +Cc1cnn(Cc2coc(-c3ccc(S(C)(=O)=O)cc3)n2)c1 +Cc1ccc(C(=O)Nc2nc(-c3ccccc3F)n[nH]2)cc1 +CCC(NC(=O)Cn1c(=O)cc(C)c2ccccc21)c1ccnn1C +CCOC(=O)CC1NCCc2ccc(O)c(F)c21 +N#CCCn1c(Cc2ccc(F)cc2)nc2cc(F)c(F)cc21 +CNCC(=O)OCc1ccc2c(c1)CCC(=O)N2C +Cc1ncc(C)c(N2CCOc3c(O)cc(-c4cccnc4)cc3C2)n1 +C=CCNC(=O)c1sc2ncccc2c1-n1cccc1 +CCCOC(=O)Cn1cc(Br)ccc1=O +CC(Nc1cccc(OC(F)(F)F)c1)c1ccncc1 +Cc1csc(NC(=O)C(OCC2CCCO2)C(C)C)n1 +CC(C)OC1CN(c2cc(N3CCOCC3)nc(N)n2)CC1O +CC(C)(C)C(=O)N1CCCC(C(=O)Nc2ccnn2C2CCCC2)C1 +O=C(COc1ccccc1)NCC1Cn2ccnc2CO1 +C=CCCC(C(O)c1ccccc1)S(=O)(=O)c1ccc(C)cc1 +N#Cc1csc(CN(CC(O)c2ccc(F)cc2)C2CC2)c1 +COc1ccc(OC)c(C(=O)C2CCCN2C(=O)C2CC2)c1 +N#Cc1cnc(NC(=O)COc2ccc(Cl)cc2Cl)s1 +CC(C)(C)Oc1ccccc1NC(=O)c1cnc(C2CCCO2)s1 +Cc1cc(C(F)F)nn1CC(=O)Nc1cccc(F)c1 +CCOC(=O)CC1NCCc2cc(Cl)cc(F)c21 +CC(=O)Nc1cccc(NC(=O)c2cccc3c2OC(C)C3C)c1 +CC(C)Cc1noc(-c2ccc(N3CCCC(C(C)(C)O)C3)nc2)n1 +Cc1ccc(CC(=O)NCc2c(C)nc3cc(=O)[nH]n3c2C)cn1 +CN(C)C(=O)Cc1ccc(NCc2c(F)cccc2Cl)cc1 +CC(NC(=O)Nc1cccc(C(=O)NC(C)(C)C)c1)c1ccccn1 +Nc1ccc(Cl)c(C(=O)NCCS(N)(=O)=O)n1 +CCn1nc(C)cc1C(=O)NCC(=O)Nc1ccccc1 +O=C(NCc1ccnc(-n2ccnc2)c1)c1c[nH]nn1 +COCCn1cc(NC(=O)NC(C)Cc2ccccc2F)ccc1=O +O=c1cc(CSc2ccc3c(c2)CCC3)nc2sccn12 +COc1ccccc1-n1nnc(C(=O)Nc2nccs2)c1C +COC(=O)CC1CN(Cc2cnc(-c3cccs3)s2)CCO1 +O=C(Cn1ccc2ccccc21)NCC1CCCO1 +CC1CC1CNC(=O)N1CCC2(CC1)OCCO2 +COc1ccccc1C(=O)CCCC(=O)NC1CC1 +COc1ccc(-c2nccc(C)n2)cc1Br +CCNC(=O)N1CCc2ccc(NC(=O)c3cc(C)sc3C)cc21 +Cc1noc2ncn(Cc3ccc(Br)cc3F)c(=O)c12 +Cc1nn(C)c2ncc(C(=O)OCc3ccccc3C#N)cc12 +CC(=O)c1nc(-c2ccc3c(c2)CCCC3)cs1 +CCCOc1cccc(-c2cc(C(=O)NC)ccn2)c1 +Cc1ccncc1NC(=O)NC(C)c1ncc(-c2ccccc2)o1 +CCCNC(=O)c1cc(NC(=O)c2cccs2)n(C)n1 +CCCN(Cc1csc(COc2ccc(C)c(C)c2)n1)C(C)=O +Cc1nnc(CNC(=O)c2sc3cccc(F)c3c2Cl)o1 +O=C(NCCN1CCOCC1)c1cccc(OC(F)F)c1 +Cc1ccc(NC(=O)c2cn3cccnc3n2)cc1C(F)(F)F +COc1cc(C(=O)Nc2ccc(N3CCCC3)nc2)ccc1C +NC(=O)C1CN(C(=O)CC(c2ccccc2)C(F)(F)F)CCO1 +COc1cc(N)ccc1NC(=O)CCOC(C)C +NC(=O)Cn1nnc(S(=O)(=O)c2ccccc2)c1N +Cc1noc(C)c1CSc1nnc(N(C)C)n1C(C)C +CC(c1ccc(F)c(F)c1)N(C)C(=O)CCSc1ccccn1 +Cc1ccc(C(=O)CSc2cccc(N)c2)cc1 +CCCNc1nc(-c2ccccc2)ncc1C(=O)OCC +Cc1cc(NC(=O)c2cc(Cl)ccn2)c2ncccc2c1 +CCc1nnc(NC(=O)NC2CCCCC2C)s1 +COCc1c(C#N)nnn1Cc1ccc(Cl)c(Cl)c1 +COc1cc(NC(=O)Cc2c[nH]c3ccccc23)ncn1 +Cc1nc2ncccn2c1C(=O)NCCS(=O)(=O)N(C)C +CC(Sc1nccn1C)C(=O)Nc1ccccc1OC(F)F +c1ccc(Cc2noc(-c3ccc(-n4cncn4)cc3)n2)cc1 +Cc1ccc(C(=O)Nc2ccc(-n3ccnc3C3CCOC3)cc2)o1 +Cc1cc(N)nn1COc1c(Cl)cccc1Cl +Cc1n[nH]c(C2CN(C(=O)CC(C3CC3)C3CC3)CCO2)n1 +Cc1noc(C(C)Sc2ncccc2Cl)n1 +COCCN(C1CC1)S(=O)(=O)c1c(C)n[nH]c1C +O=C(NCc1nncn1C1CC1)Nc1nnc(C2CCCCC2)s1 +COC(=O)c1cc(CNC(=O)C2CCCN2C(=O)C2CC2)oc1C +Cc1nn(C)c(C)c1CCC(=O)NC(C)c1cn2ccsc2n1 +COc1ccc(CNc2c(F)cccc2F)c(OC)c1 +Cc1ccc(NC(=O)Cn2ccc(C(F)(F)F)n2)c(O)c1 +O=C(Nc1cc(-n2cccc2)ccc1F)c1ccncc1 +COc1cccc(-c2nc(C)nc3c2CNCC3)c1 +Cc1cccc(C)c1NC(=O)CCCS(=O)(=O)c1ccc(O)cc1 +O=C(NCc1ccccc1Cl)C1CCN(c2cnccn2)CC1 +Cc1ccc(C(C)NCC(=O)N2CCOCC2)cc1 +Cc1nc2ccccc2n(CC(=O)NCCc2cccs2)c1=O +CC1Cc2ccccc2N1CCNC(=O)C1(C#N)CCCC1 +CCOc1cc(F)ccc1NC(C)c1cccnc1 +Cc1cc(C)n2nc(C(=O)NCCc3ccc(F)cc3C)nc2n1 +Cc1c(C(=O)Nc2nccs2)cccc1-n1cnnc1 +CCOc1ccc(CNC(=O)CC(C)n2cccn2)cc1 +CCCNc1ccc(C#N)cc1NC(=O)c1ccc2nncn2c1 +CNS(=O)(=O)c1ccc(C(=O)NCC2CCCC(C)C2)cc1 +CSc1ccc(CN(C)Cc2ccc(C#N)cc2)cc1 +CCC(NCc1ccc(S(C)=O)cc1)c1nccs1 +Cn1cc(CNc2ccc(SC(F)F)nc2)cn1 +O=C(Nc1ccnc2ccnn12)c1ccccc1Cl +Cc1cc2nc(N)nn2cc1-n1nnc2ccccc21 +O=C(Cc1ccccc1F)NCC(O)COc1cccc(F)c1 +CCn1cc(C(=O)NCc2nnc(C)o2)c(=O)c2ccc(C)nc21 +CSc1ccc(C)c(C(=O)NC2CCCCNC2=O)c1 +COC1CCCN(C(=O)Nc2cccc(CCC(=O)N(C)C)c2)C1 +N#CC(NC(=O)c1ccc(C(F)(F)F)cc1)c1cccs1 +Cn1cc(C(=O)Nc2ccc(N3CCCC3=O)cn2)c(C(C)(C)C)n1 +COCc1ncn2c1CN(C(=O)c1cccc(C)c1)CC2 +COc1ccc(Cl)cc1C(=O)C1CCC(=O)O1 +N#Cc1ccccc1S(=O)(=O)Oc1ccccc1Br +CSc1nc2ncc3c(n2n1)CC(c1ccc(F)cc1)CC3=O +COc1ccc(CCNC(=O)C2CC=CCC2)cc1 +CC(C)OCCC(=O)Nc1ccccc1CN1CC(C)OC(C)C1 +CCn1c(SCc2n[nH]c(=O)[nH]2)nnc1-c1ccc(OC)cc1 +N#CCCN(Cc1ccco1)Cc1ncc(-c2ccccc2)o1 +COc1ccc(-c2cnc(CSc3nccn3C3CC3)o2)cc1 +Cc1ccc(-c2cc(C(=O)NCc3ccncc3)no2)cc1 +Cn1nc(-c2cccc(N)c2)c2c1CCCC2CC#N +Cc1cc(C(=O)N2CCC(c3nc4ccccc4s3)CC2)n(C)n1 +Cc1cccc(Cl)c1NC(=O)N1CCN(c2cccnn2)CC1 +O=C(Cn1cnc2sccc2c1=O)Oc1cccc2ccccc12 +O=C(c1ccc(OCC(F)F)nc1)N1CCC(Cc2ccccc2)C1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCC2(CC1)OCCO2 +O=C(NC1CCCCC1)N1CCCN(C(=O)c2ccsc2)CC1 +N#Cc1cnc(SCC(=O)N2CCCCCC2)nc1N +Cc1nc(-c2cc(C(=O)Nc3ccn(C)n3)n(C)c2)cs1 +CC(=O)NCCCCCC(=O)Nc1ccc(F)cc1Cl +c1cc(CN2CC3OCCN(CC4CC4)C3C2)n[nH]1 +COCCNS(=O)(=O)c1ccc(N2CCCC2=O)cc1C +CCn1cnnc1CNC(=O)Cc1ccc(F)cc1F +Cc1ccc2nc3sc(C(N)=O)c(N)c3cc2c1 +Cc1cc(C)n2nc(C)c(C(=O)NCCc3ccc(F)cc3C)c2n1 +CCN1CC(C(=O)NC(C)c2ccc(OC)c(F)c2)CC1=O +C=C(C)C(C)(O)C#CCN1CCCCC1c1cccnc1 +Cc1ccc(NC(=O)c2cnn(-c3ccccn3)c2C)cc1 +Cc1ccccc1S(=O)(=O)N(CCCO)C1CC1 +CCc1nc(CNc2cc(NC(C)=O)ccc2F)cs1 +COc1ccnc(NC(=O)c2ccc(C(N)=O)cn2)c1 +CCc1nc2cc(NC(=O)Cc3c(C)nc(C)[nH]c3=O)ccc2o1 +Cc1n[nH]cc1NC(=O)c1cccnc1-n1cncn1 +Cc1csc(=NS(=O)(=O)c2ccc3c(c2)CCN3)[nH]1 +CCCN(CCC)C(=O)Cn1c(CC)nc2c(N)cccc21 +FC(F)(F)CN1CCCC(c2nnc3n2CCCCC3)C1 +COc1ccc(NC(C)=O)cc1Nc1ncnc2ccsc12 +CC(C)c1ccc(S(=O)(=O)N(C)CCC#N)cc1 +NC(=O)C1(CNC(=O)COc2ccc3c(c2)CCC3)CCOCC1 +Cc1ccccc1CC(=O)NCc1noc(-c2cccc(Cl)c2)n1 +CC(C)c1noc(CCC(=O)Nc2ccccc2O)n1 +O=C(CCNC(=O)c1ccc(F)cc1F)NC1CCCCC1 +CC(CO)NC(=O)c1cnn(-c2ccc(Cl)cc2)c1C(C)C +Cc1nc(C)c(CN2CCOCC(Oc3ccccc3)C2)s1 +Cc1ccn(Cc2nc(C(C)(C)C)cs2)c(=O)c1C#N +COc1ccccc1NCC(=O)N(C1CC1)C(C)c1ccco1 +CN(C)c1nc(Cn2nc(C3CC3)nc2C2CC2)ns1 +O=C(Nc1ccc2c(c1)C(=O)NCCO2)c1cccc(Cl)c1 +c1ccc(-c2nnc(CSc3ncccn3)o2)cc1 +O=C(Cc1ccc(Br)cc1)NCCc1ccco1 +CC(=O)NC(C)C(=O)N(Cc1ccc(Cl)c(Cl)c1)C1CC1 +COC(=O)C(Nc1cc(-c2ccccc2)nc2ncnn12)C(C)(C)C +O=C(Nc1ccccc1Cl)C1CC(=O)n2c(nc3ccccc32)N1 +Cc1noc2nc(C3CC3)cc(C(=O)NC3CCCCC3)c12 +CC(C)NC(=O)Cn1cnc2c(cnn2CCO)c1=O +CCOc1ccc(C(=O)N2CCC(C(N)=O)CC2)cn1 +COc1ccccc1-c1noc(CSc2nnnn2C)n1 +COc1ccc(S(=O)(=O)NC(C2CC2)C2CC2)cc1 +O=C(Nc1cccnc1-n1cncn1)c1ccc(Cn2cncn2)cc1 +Cc1cc(Sc2ccc(O)cc2)n2ncnc2n1 +Cc1cc(F)ccc1C(=O)N1CCN(C(=O)N(C)C)CC1 +CCOC(=O)N1CCN(C(=O)CCc2ccccc2OCC)CC1 +O=C(NCC(O)COc1cccc(F)c1)c1cccc2c1OCCO2 +Cc1ccc2cc(C(=O)NCc3cnc(C)s3)[nH]c2c1 +COC(=O)c1ccccc1OC(=O)C1CC2CCC1C2 +COC(=O)c1cccc(CCNS(=O)(=O)N2CCCCCC2)c1 +CCC(=O)Nc1ccc(-c2nc3ncccc3o2)cc1C +Cc1noc(C)c1COC(=O)c1ccc(N(C)C)cc1 +Cc1ccc(S(=O)(=O)NCCc2nnc3n2CCC3)cc1C(N)=O +CC(=O)Nc1nc(C(=O)Nc2ccccc2-c2ccccc2)cs1 +COc1ccc(-c2cc(COC(=O)c3ccccn3)no2)cc1OC +Cc1ccc(C(=O)NCc2ccccc2N2CCCC2)c(=O)[nH]1 +Cc1cc(C)n(Cc2cccc(C(=O)N(C(C)C)C(C)C)c2)n1 +CCOCCNC(=O)c1nnn(-c2cccc(F)c2)c1C(F)(F)F +Cc1cc(NC(C)c2cccs2)n2ncnc2n1 +CSc1ccc(NC2CCCc3c2cnn3C)cc1 +CCN1CCN(C(=O)CC23CC4CC(CC(C4)C2)C3)CC1 +CCNc1nc2c(c(=O)[nH]c(=O)n2C)n1CCO +Cc1cc(C)cc(NCc2ccc(S(C)=O)cc2)c1 +CCOc1ncccc1CNC(=O)C1CCCN1C(=O)C1CC1 +COc1ccc2c(c1)CCCC2CNC(=O)c1c(C)noc1C +CCOc1ccc(NC(=O)c2scnc2CC)cc1CO +CC(=O)NC1CCCN(C(=O)NCCNc2cnccn2)C1 +Cc1cc(NC(=O)COc2ccc3c(c2)OCO3)no1 +N#Cc1cc(S(=O)(=O)Oc2ccc3c(c2)CCC3)ccc1F +COc1ccc(CNC(=O)C(C)OC(=O)C=C(C)C)cc1 +O=C(COc1ccc(F)cc1Cl)N1CCOCC1 +CNC(CCOc1ccc(OC)cc1)C(F)(F)F +CCc1csc(CNC(=O)c2ccc(NC3CCCC3)nc2)n1 +Oc1ccc(Cl)c2c1CCNC2c1cnccn1 +O=C(Cc1c(Cl)cccc1Cl)Nc1ccon1 +O=C(N1CCN(CCO)CC1)C(O)(c1ccccc1)c1ccccc1 +CC(C)NC(=O)N1CCCC(OCc2nc(-c3ccccc3)no2)C1 +COc1ccc(CN(C)Cc2cc(F)c(F)cc2F)cc1O +CCn1c(CNC(CCO)c2ccccc2)nc2ccccc21 +CC(Nc1ncnc2c1cnn2C)c1ccc2c(c1)NC(=O)CO2 +O=C(Nc1nnc(CC2CCCCC2)s1)C1COCCO1 +COC(=O)C1(N(C)C(=O)c2oc(C)nc2C)CCCCC1 +CC(O)CN1CCN(C(=O)CCOC(C)C)CC1 +COc1ccccc1CNC(=O)c1ccc(OC(C)C)cc1 +O=C(CNC(=O)c1ccccc1)Nc1ccccc1O +O=C(c1ccoc1)N1CCN(c2nc3cccnc3s2)CC1 +COc1ccccc1OCC(=O)c1cn(C)c2ccccc12 +c1cncc(Oc2ncnc3c2oc2ccccc23)c1 +CC(=O)c1cc(C(=O)OCCNC(=O)c2ccncc2)n(C)c1 +Cc1ccc(N(Cc2ccccc2)S(C)(=O)=O)cc1 +Cc1nc(CNC(=O)c2c(C)c3ccccc3oc2=O)c(C)s1 +c1ccc(-n2nnnc2Sc2ccc3nccnc3n2)cc1 +CCOCCCC(=O)Nc1cc(F)ccc1OC +CCCn1c(=O)c2c(OCC)c(C)cnc2n(C)c1=O +CC1(C)C(OCc2ccccc2)C2C(CO)CC(=O)OC21 +COCCCC(=O)N1CCN(c2cccc(OC)c2)CC1 +O=C(NCC1CN2CCCC2CO1)c1cnc2ccccc2n1 +O=C(NCCCNC(=O)N1CCC1)c1ccccc1F +FC(F)Oc1ccc2c(c1)CCNC2CC1CC1 +Cc1nc2cc(C(=O)Nc3ccc4nc[nH]c(=O)c4c3)ccc2n1C +Cc1ccc(OC(=O)Cc2cccc(OCC#N)c2)cc1 +COC(=O)CC1CCN(c2ccc(C#N)cc2Cl)CC1 +CC1Oc2ccccc2N(CC(=O)Nc2ccc3c(c2)COC3)C1=O +CCOC(=O)c1ccc(C(=O)NCC(C)(O)c2ccccc2)nc1C +Nc1cc(F)cc(S(=O)(=O)NCC2CCC2)c1 +CCOC1CCN(C(=O)NCCc2ccn(-c3ccccc3)n2)CC1 +O=S(=O)(NCC1COc2ccccc2O1)c1ccc2c(c1)CCC2 +O=C(NCCc1nc(-c2ccccc2)n[nH]1)c1ccncc1 +COc1cc(Cl)ccc1C(=O)N1CCc2sccc2C1 +COc1cc(F)ccc1-c1ccnc2c(C(N)=O)cnn12 +O=C(NCCN1CCOCC1)C1CCN(C(=O)c2ccco2)CC1 +CCN(CCn1cc(C2CCOC2)nn1)c1cccc(C)c1 +Cc1ccc(-c2ccc(C(=O)NCCN3CCOCC3)c(=O)[nH]2)cc1 +CC(C)C(C#N)NS(=O)(=O)CCc1ccccc1 +COc1cccc(C(C)Nc2cc(OC)ncn2)c1 +N#Cc1ccc(NCc2ccccc2C#N)cc1Cl +COc1cc(OC)cc(-c2nnc3sc(C)nn23)c1 +COc1cccc(S(=O)(=O)C(C)C(=O)Nc2cc(C)on2)c1 +Cc1cccc(COc2cccc(C(=O)Nc3nc(C)no3)c2)c1 +Cc1nnc(SCC(=O)NCc2ccc(OC(F)F)cc2)n1N +COc1cc(C(=O)Nc2cc(NC(C)=O)ccc2OC)ccc1C +Nc1c(Cc2ccccc2Br)nc[nH]c1=O +Cc1n[nH]cc1NC(=O)COc1ccc(F)cc1Br +Cc1occc1C(=O)NCCc1nc2ccccc2s1 +Cc1cc(OCn2ccc(N)n2)cc(C)c1Cl +CC1CCCCN1c1ncnc2c1cnn2-c1ccccc1 +CCc1cccc(CC)c1NC(=O)CSc1ncc(C#N)c(N)n1 +CCCc1nnc(NC(=O)CCC(=O)Nc2cc(C)ccc2C)s1 +O=C(Nc1nc2c(s1)CCC2)C1CCCCC1 +CC(C)(C)C(=O)NCCNC(=O)c1cnccn1 +COc1cc(NC(=O)C(C)OC(=O)c2cnc(C)cn2)cc(OC)c1 +O=C(Cn1nc(-c2ccc(F)cc2)oc1=O)Nc1ccc(Cl)cc1 +CC(=O)N1CCC(C(=O)N(Cc2cccnc2)CC2CCCO2)CC1 +Cc1cccn2cc(CNC(=O)c3ccc(F)c(F)c3)nc12 +O=C(Cn1ccnc1-c1ccccc1)N1CCOCC(O)C1 +Cc1n[nH]c(C)c1Sc1ccccc1NC(=O)CC1CCC(=O)N1 +Cc1cc(CNc2cccc(N3CCCC3=O)c2)n[nH]1 +N#CCc1ccc(C(=O)N2CCCCC2CCO)cc1 +O=C(NCc1cccnc1OC1CCCC1)c1ccsc1 +O=C(c1cccc(Cl)c1)N1CCC(S(=O)(=O)c2ccccc2)C1 +CC(C)CCC(C)(O)CNC(=O)Cc1ccc[nH]1 +COCC(=O)n1nc(-c2cccs2)nc1NCc1ccccc1 +Cn1cccc1C(=O)NCCNc1nnnn1-c1ccccc1 +CCN(Cc1coc(-c2ccc(S(C)(=O)=O)cc2)n1)CC(C)C#N +CC1Sc2ccccc2N(CC(=O)N(C(C)C)C(C)C)C1=O +O=C(NCc1cn(-c2ccccc2)nn1)NCc1ccccc1Cl +Cc1cc(C(=O)NCC2(c3ccccc3C)CCOCC2)[nH]n1 +CN(Cc1cccc(C#N)c1)C(=O)C1CC1c1ccc(F)cc1 +CCS(=O)(=O)c1ccc(NC(=O)C2CC3C=CC2C3)cc1 +CCC(NC(=O)NCCc1cc2ccccc2[nH]1)c1nc(C)cs1 +O=C(c1ccc(-c2nc(C3CC3)no2)cc1)N1CCCC1c1ccc[nH]1 +CC(=O)Nc1ncc(S(=O)(=O)Nc2cccc(C)c2)s1 +COCCN(Cc1ccc(C#N)cc1)C(=O)c1cc(C)cc(C)c1 +N#Cc1ccc(N2CCC(C(=O)Nc3ccccn3)CC2)c(F)c1 +O=C(NCC1CCN(c2ccccc2)C1)c1scnc1C1CC1 +CSc1cccc(NC2=Nc3cc(N)ccc3OC2C)c1 +CCC(CC)n1nc(C)cc1NC(=O)Cc1cnc2c(C)cccn12 +COc1cccc(NC(=O)COc2ccccc2N)c1 +O=C(Nc1nccs1)C1CCCN1C(=O)CCc1ccccc1 +Cn1nc(C2CCCO2)c(-c2nc3ccccc3n2C)c1N +COCC(O)CN(C)C(=O)c1csc(-c2ccccc2OC)n1 +CNc1ncnc(Nc2cc(C(=O)OC)cc(C(=O)OC)c2)c1N +O=c1c(=Cc2ccco2)sc2nc(-c3cccs3)nn12 +Cn1cnc(CNC(=O)NC2Cc3ccccc3C2)n1 +C1=CCC(Cn2ncc3[nH]c(C4CCOCC4)nc32)CC1 +CN(C(=O)c1ccn(-c2ccccc2Cl)n1)C1(C#N)CCC1 +CC(C)NC(=O)Nc1ccc(C(=O)NCc2ccc(C#N)cc2)cc1 +CCNC(=O)N1CCc2cccc(S(=O)(=O)N(C)C)c21 +COc1ccc(F)c(NC(=O)Cc2cccc(C)c2)c1 +COc1ccccc1-c1noc(-c2cnc3cc(C)ccn3c2=O)n1 +CSc1nsc(NC(=O)Cc2ccc(F)cc2)n1 +O=C(Nc1cnn(-c2ncncc2N2CCCC2)c1)c1ccco1 +CC(C)(C)C(=O)NCCCC(=O)NC1CCCCC1 +COc1ccc(F)cc1NC(=O)Cc1cccnc1 +CCn1cnnc1C1CCN(C(=O)c2ccc3c(c2)CCCC3)CC1 +COc1ccccc1CC(=O)NCc1cccs1 +CCCN(CC1CC1)C(=O)c1ccc(N2CCCC2=O)cc1 +CC1CCCCN1S(=O)(=O)c1ccccc1C(F)(F)F +Cc1nc2ccc(NCC(=O)N(C)CC(=O)NC3CC3)cc2s1 +COc1ccc(CCCCn2cc(N)cn2)cc1C +NC(C(=O)NCc1ccc[nH]1)c1cc(F)cc(F)c1 +COc1cc(CCC(=O)c2cccnc2)cc(Cl)c1O +COc1ccc(C=Cc2nnc(NC(=O)c3ccco3)s2)cc1 +CCOCCOCC(=O)Nc1ccc(F)c(N)c1 +CCS(=O)(=O)N1CCC(NC(=O)c2ccc(F)c(F)c2)CC1 +Cc1ccc(CNC(=O)Nc2cc(C(N)=O)ccc2C)c(N(C)C)c1 +CNS(=O)(=O)c1cc(C(=O)Nc2cccc(C)c2)cc(C)c1C +CCCCOC(=O)Cn1nnc2sc3c(c2c1=O)CCCC3 +COCCN1CCN(c2ncnc3[nH]ncc23)CC1 +Cc1cc2c(cc1Br)OCCC(=O)N2 +Cc1n[nH]c(C(=O)NCCNc2ncccn2)c1Br +CCCOC1CCCN(c2cc(C)ccc2C#N)C1 +N#CC(NCCCc1ccccc1)c1ccccn1 +CCn1cc(CNC(=O)CCn2cc(Br)c(C)n2)cn1 +O=C(c1ccc2sccc2c1)N1CCC(c2ccncc2)CC1 +O=C(Nc1cc[nH]n1)c1csc(-c2ncccn2)n1 +COc1cccc(C(O)CNc2c(C)cc(C)cc2C)c1 +COc1ccc(Cl)cc1CNc1cccc(NC(C)=O)c1 +C=CCn1c(C)nnc1SCC(=O)C1C2CC3CC(C2)CC1C3 +CC(C(=O)OCC1COC(C)(C)O1)N1CCc2ccccc2C1 +CC1CCCC(OCC(=O)Nc2ccc(C#N)cc2)C1 +CCS(=O)(=O)NCc1cccnc1OC(C)C +CC(C)(C)C(=O)NCC1CCCN(C(=O)c2cccc(Cl)c2)C1 +COc1ccc(NC(C)=O)cc1-c1[nH]nc(C)c1N +NC(=O)c1cnc(N2CCOC(c3ccc(F)cc3)C2)c(Cl)c1 +CCNc1nc(NCC)nc(NS(=O)(=O)c2ccc(C)cc2)n1 +Cc1noc(CSc2nc(-c3ccco3)nc3ccccc23)n1 +Cc1cccc(COCc2n[nH]c3c2CN(C(=O)NC2CC2)C3)n1 +C#CCOCC1CCN(C(=O)Nc2cccc(OC)c2OC)CC1 +CCCn1c(N)c(CN2CCOCC2)c(=O)[nH]c1=O +COC(=O)C1CCN(C(=O)c2c(C)oc(C)c2C)CC1 +CC(=O)N1CCN(c2nc(-c3cccnc3)nc3ccccc23)CC1 +O=C(c1cccnc1)N1CCC(n2cccc2)CC1 +CCc1ccccc1OC(C)(C)C(=O)N1CCNCC1 +O=C1CCCCN1c1ccc(S(=O)(=O)Nc2ncccn2)cc1 +Cc1cc2c(cc1F)C(c1cnccc1Cl)NCC2 +O=C(NCc1ccccc1Cn1cccn1)c1n[nH]c2ccccc12 +CC(C)C(C)(C#N)NC(=O)CN(C)Cc1c(F)cccc1Cl +Cc1occc(=O)c1OCC(=O)NCc1cccc(Cl)c1 +CC(=O)N1CCC(NC(=O)C2CCCN2S(C)(=O)=O)CC1 +CC(=O)NCc1cnn(-c2ccc(C(=O)NCc3cccnc3)cc2)c1 +Cn1c(SCC(=O)Nc2ccc(F)cc2)nnc1-c1cccs1 +Cc1c(C(=O)NCCOCc2ccccc2)cnn1-c1ccncc1 +CCCN(CCC)C(=O)Cn1nnnc1C(C)(C)C +Cc1ccc(-c2csc(-c3cccn3CC(=O)NC3CC3)n2)cc1 +O=C(CNC(=O)Cc1ccccc1)N=c1[nH]nc(-c2ccco2)[nH]1 +O=C(Cc1cccs1)Nc1cnc(N2CCOCC2)nc1 +Cc1cc(N)nc(SCC(=O)Nc2c(C)cccc2C)n1 +CCc1cccc(OC(C)(C)C(=O)n2ccnc2)c1 +O=C1CC(c2ccccc2)Oc2cc(O)cc(O)c21 +CC(C#N)CNC(=O)c1cccc(OCc2cccs2)c1 +Cc1nc(CN2CCN(c3ncnc4onc(C)c34)CC2)cs1 +CCOCC(=O)Nc1ccc(-n2ccc(C(N)=O)n2)cc1 +CCCc1ccc(C(=O)N2CC3C4CCC(O4)C3C2)cc1 +COc1cc(-c2cc(C(=O)OC(C)C)[nH]n2)ccc1OC(C)C +CN1CCCc2cc(CCNC(=O)COc3ccccc3)ccc21 +CC(C)(CO)N(CCO)C(=O)c1ccc(F)c(F)c1 +COC(=O)c1cc(-c2ccc(OC)c(OC)c2)no1 +CNC(=O)CSc1nc(CCC2CCCC2)n[nH]1 +O=C(Nc1ccc(-n2cnc3ccccc32)cc1)c1ccsc1 +Nc1cccc(NC(=O)COCc2ccccc2)c1 +CCC(=O)Nc1ccc(-c2nc(C)cc(=O)[nH]2)cc1 +CCCc1cc(C(=O)N2CCN(C3CCCCC3O)CC2)n(C)n1 +Cc1cccc(COC2CN(Cc3cc(C)on3)C3CCCOC23)n1 +CC1CN(C(=O)CCc2nncn2C)CCC1(O)C1CCC1 +O=C(CC1(Cn2cnnn2)CCCCC1)NCc1cccnc1 +CSc1ccc(CN(C)S(=O)(=O)c2cccs2)cc1 +CCNC(=O)CNc1ncnc2[nH]nc(SC)c12 +Cc1cc(C(F)(F)F)nc(CCNc2ccc3cc[nH]c3n2)n1 +CC(=O)Nc1cccc(NC(=O)CCCNC(=O)c2cccs2)c1 +O=C(COc1ccc(F)cc1)Nc1ccc(N2CCCC2=O)cc1 +Cn1cc(C#N)cc1C(=O)OCCNc1ccc(C(F)(F)F)cn1 +CC(C)C(=O)Nc1ccc(OCC(=O)N(C(C)C)C(C)C)cc1 +Cc1ccccc1CN(C)C(=O)C(C)Sc1nc(C)c(C)o1 +CC(C)OC(=O)C1CCCN1C(=O)c1cccc(-c2ccoc2)c1 +CCOC(=O)c1cnn(C2CCCN(C(=O)c3cc(C)no3)C2)c1 +CC(=O)C1CNc2ccc(Cl)cc2C1(O)c1ccccc1 +CCCc1noc(CNc2cccc3c2OCCO3)n1 +CCOc1ccc(NC(=O)Cn2nnc(C(C)=O)c2C)cc1 +Cc1nn(C)cc1S(=O)(=O)N1CCN(Cc2ccccc2)CC1 +O=S(=O)(NCc1ccc(C(F)(F)F)cc1)c1cccs1 +CCC(=O)Nc1ccc(NC(=O)NCCOC)cc1C +CCc1onc(C)c1NC(=O)c1cnc(-c2cccs2)s1 +CC1(CNC(=O)c2cn3cc(Cl)ccc3n2)COC1 +CCS(=O)(=O)Nc1ccccc1-c1nc2ccccc2[nH]c1=O +Cc1ccccc1OCCN1CCN(C(=O)c2cccs2)CC1 +O=C(Nc1cccc(-c2nnco2)c1)c1cccnc1OCC(F)F +CC(=O)Nc1cccc(NC(=O)c2cc(N)ccn2)c1 +CCOc1ccc(C)cc1-c1cn2cc(N)cc(OC)c2n1 +COCc1noc(CNC(=O)Nc2nc(C)n(C)n2)n1 +COc1cccc(-n2c(SCC(N)=O)nnc2-c2ccco2)c1 +CCN(CC(C)C#N)C(=O)CNc1ccc(-n2cncn2)cc1 +O=C(c1c[nH]c2cccc(F)c12)N1CCCCC1c1ncon1 +Cc1ccc(NC(=O)c2ccc(C#N)cn2)cc1S(C)(=O)=O +COc1cc(C(=O)N(C)C)ccc1NC(=O)NCc1cnn(C)c1C +CC(C)(C)OC(=O)Nc1ccc(NC(=O)c2ccncc2)cn1 +Cc1cc(N)cc(C)c1NC(=O)c1ccc(Br)cc1 +CCCNC(=O)N(Cc1nccn1Cc1ccccc1C)C1CC1 +CC(=O)NCc1ccc(C(=O)Nc2ccnn2C2CCCCC2)cc1 +O=C(Nc1c[nH]c2ccccc12)c1cnn(Cc2ccccc2)c1 +Cc1nc2ccc(NC(=O)c3ccc(-n4cnnn4)cc3)cc2s1 +Nc1cccc2oc(=O)n(CCCCOc3ccccc3)c12 +Cc1nn(C)c2ncc(NC(=O)C3CC(=O)N(C)C3)cc12 +Cc1cc2oc(=O)cc(CC(=O)N3CCCC3)c2cc1C +Cc1ccccc1OCC(=O)Nc1ccc(S(C)(=O)=O)cc1 +CC(=O)N1CCc2c([nH]c3ccccc23)C12C(=O)N(C)c1ccccc12 +CCN(Cc1ccccc1)C(=O)CSc1nc(N)cc(=O)[nH]1 +COc1ccc(-c2nc(C(=O)N3CCC3(C)C)cs2)cc1 +Cn1c(=O)c2c(nc(OC3CCCC3)n2C)n(C)c1=O +Cc1ccc(-c2nnc(N(C)C(=O)c3ccccn3)s2)cc1 +Cc1cccc(C(=O)N2CCCc3ccc(F)cc32)n1 +COc1ccc2ncc(OC)c(Br)c2n1 +CCOC(=O)C1CCN(C(=O)Nc2ccc3c(c2)nc(C)n3C)CC1 +CN(C)c1ccc(Cl)cc1NC(=O)Nc1ccc2c(c1)CC(=O)N2 +Cc1ccccc1COC1CCN(C(=O)c2nccnc2N)CC1 +Cc1cc(C(=O)CSc2nncs2)c(C)n1CC(F)(F)F +O=C(CNC(=O)c1cc2cc(Cl)cnc2[nH]1)NC1CCCC1 +CC(=O)N(C)c1ccc(NC(=O)Cc2ccc(F)cc2)cc1 +CC(C)c1n[nH]c(C2CN(C(=O)c3ccc(=O)n(C)n3)CCO2)n1 +CC(CCc1ccccc1)CC(=O)N1CCN(CCO)CC1 +CCCOc1cc(C)ccc1NC(=O)c1ccc(OC)nn1 +Cc1nnc(NC(=O)c2cc(C)n(C(C)(C)C)n2)s1 +CCN(CC(=O)NC(C)C)C(=O)c1cnc(C2CCCO2)s1 +Cc1nn(C(C)C)c2cnn(CC(=O)NC(C)c3ccncc3)c12 +CC(C(=O)N1CCCCC1)n1c(=O)oc2ccccc21 +Cc1ccc(NC(=O)CCN2CCOCC2)cc1Br +Cc1cccc(NC(=O)CSc2nc(C)cc(C)n2)c1 +CCCN(CC(=O)OCC)C(=O)c1cccc(C)c1O +COCc1ccccc1C(=O)N1CCC(CNC(=O)OC(C)(C)C)C1 +C=CCn1c(C)nnc1SCC(=O)Nc1ccc(NC(C)=O)cc1 +COC(=O)c1ccccc1NC(=O)CC(NC(C)=O)c1ccccc1 +O=C(Nc1cccnc1)c1ccc(CN2CCCC2=O)cc1 +Cc1ccc(-c2cc(N)c(=O)n(CC(=O)NC3CC3)n2)s1 +Cc1ccc(S(=O)(=O)Nc2cc3[nH]c(=O)[nH]c3cc2C)cc1F +CCN(CC)C(=O)c1ccc(NC(=O)c2cc(C)n[nH]2)cc1Cl +CN1CCN(C(=O)c2n[nH]c3c2CN(Cc2ccoc2)CC3)CC1 +COCCN(C)C(=O)Nc1ccc(CN(C(C)=O)C2CC2)cc1 +COC(=O)c1cc(CNC(=O)Nc2ccc(Cl)cc2C)oc1C +CCc1nc2c(NC(=O)Cc3ccc(C)cc3)cccn2n1 +COc1ccc(OCCCC(=O)N=c2sccn2C)cc1 +NS(=O)(=O)CCCNc1ncnc2ccsc12 +Cc1cccc(-n2ncc(N)c2C(F)(F)F)c1C +CC(C)OC(=O)CCCNC(=O)NC1CCCCC1 +C=C(C)COC(=O)Cc1cc(C(C)=O)ccc1OC +Cc1ccc(-c2cnc(CCC(=O)Nc3nc[nH]n3)o2)cc1 +COCc1cccc(C(=O)NCc2ccccc2F)c1 +CC(NC(=O)c1ccc2c(c1)N(C)CC2)C(=O)NCc1ccccc1 +Cc1ccccc1NC(=O)c1cc(S(C)(=O)=O)ccc1C +CNS(=O)(=O)c1cc(C(=O)N2CCCCC2)ccc1OC +COC(=O)Cc1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1 +Cc1cc(C(=O)NCc2ccc(OCC(F)(F)F)nc2)c(C)s1 +Cc1nn(C)cc1C(=O)COc1ccc(S(C)(=O)=O)cc1 +CCOC(=O)C1CC(=O)N(c2ccc(NC(=O)C(C)C)cc2)C1 +Cc1cccc(NC(=O)C2CCCN(S(=O)(=O)c3c[nH]cn3)C2)n1 +CCSc1nnc(NC(=O)Cc2cccc(OC)c2)s1 +COC(=O)c1ccc(C)c(NC(=O)CCC2C(=O)N=C(C)N=C2C)c1 +COc1cccc(C(=O)Nc2cc(C(N)=O)ccc2C)c1F +CCc1cccc(NC(C)C(=O)N(C)CCC#N)c1 +COc1ccc(Nc2nnc(-c3cccnc3)o2)cc1C +CCOc1ccc2nc(C(=O)NC(C)c3ccccc3)cn2n1 +C=CCOc1ccc2c3c(c(=O)oc2c1C)CCC3 +O=C(c1ccsc1)N1CCn2c(Cn3cncn3)cnc2C1 +CCOC(=O)N1CCN(C(=O)c2cn(C)c3ccccc23)CC1 +Cc1ccc2nc(NCC(=O)N(C)C)nc(-c3ccccc3)c2c1 +Cc1cc(S(=O)(=O)NC(C#N)CC(C)C)ccc1Cl +O=C1CN(C(=O)c2ccccc2Oc2ccccc2)CCN1 +COc1ccc(CN(C)C(=O)NC(C)C(=O)N2CCCCC2)cc1C +O=C(c1cn(Cc2ccccc2)nn1)N1CCC(Oc2ccccc2)C1 +CCCn1nccc1NC(=O)c1ccc2cc[nH]c2c1 +CCc1cc(=O)[nH]c(-c2cccc(C(F)(F)F)c2)n1 +COc1cc(C)c(C(=O)Nc2ccccc2SC)cc1OC +CC(C)C(C)NC(=O)NCCc1nccn1Cc1ccccc1 +COCCOc1ccc(Cl)cc1S(=O)(=O)Nc1ccccc1 +Cn1c(C(=O)N(CCO)Cc2ccccc2)cc2ccccc21 +COc1ccc(C(CO)C2CCCC2)cc1OC +O=C1CCc2cc(OCC(=O)OCC#Cc3ccccc3)ccc2N1 +COc1ccc(-c2nc(CCNC(=O)Cn3cc(C)cn3)co2)cc1 +COc1cc2c(c(OC)c1)C(c1ccccc1F)CC(=O)N2 +CC(C)(C)C(NC(=O)Cn1ccc(=O)c2ccccc21)C(N)=O +CC(=O)NC(CC(=O)Nc1ccccc1)c1ccccc1 +CCCn1nnc2cc(C(=O)Nc3ccc4c(c3)OCCO4)ccc21 +N#Cc1ccsc1NC(=O)c1ccc2c(c1)CCCC2 +O=C(C1CCOC1)N1CCC(Oc2cccc(C(F)(F)F)c2)CC1 +CCOc1cc(F)ccc1NC(=O)c1ccc(-n2cc(C)cn2)cc1 +CC(=O)N1CCc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc21 +CC(=O)c1cc2c(cc1Br)OCCCO2 +CCN1CCN(C(=O)C(C)NC(=O)c2ccc(C(C)(C)C)cc2)CC1 +Cc1nc(CC(=O)N2CCC(c3nnc4n3CCC4)CC2)cs1 +Cc1ccc(NC(=O)c2ccc(CSc3nccn3C)o2)c(O)c1 +COCc1ccc(C(=O)N2CCN(C(=O)C3CCCC3)CC2)o1 +c1ccc2c(c1)CC(c1ccc3c(c1)OCCO3)N2 +COc1ccnc(NCC(=O)N2CCN(c3ccccc3)CC2)n1 +CCC(=O)Nc1cccc(C(=O)NCc2cccc3[nH]ccc23)c1 +O=c1[nH]c(C2CCCOC2)nc2ccc(Cl)cc12 +CCOC(=O)c1cnn(-c2ccc(C)cc2)c1C#N +COc1cccc(C(=O)NCC(C)(O)c2ccc(F)cc2)c1O +CN(CC(=O)N(C)C1CCc2ccccc2C1)C(=O)c1ccccc1 +O=C(NCC(F)(F)F)C1COc2ccc(F)cc2C1 +CC(O)c1nc2ccc(F)cc2n1Cc1cccc(C#N)c1 +COc1ccc(S(=O)(=O)NCCc2ccccc2)c2cccnc12 +Cc1cccc(NC(=O)c2ccc(N3CCCC3)nn2)c1 +CC(=O)N(C)Cc1cncc(C2CCCN2Cc2ccccc2)n1 +COc1cccc(CNS(=O)(=O)c2cccc(C)c2)c1 +NC(=O)CCc1ccc(S(=O)(=O)N2CCCCCC2)cc1 +CC(Sc1n[nH]c(=O)n1C1CC1)C(=O)c1ccc(Cl)cc1 +CCOC(=O)C1CCN(C(=O)c2ccc3ccccc3c2)CC1 +COC(=O)c1ccc(C(=O)NCc2cnc(C)s2)nc1 +Cc1occc1C(=O)NC(C)c1cccc(Br)c1 +CCN(CC)S(=O)(=O)c1cnc(NC(C)=O)s1 +CN(C)S(=O)(=O)c1ccccc1CNc1cccc(F)n1 +C=CCNc1nnc(SC(C)C(=O)N2CCCCC2CC)s1 +CC(NC(=O)CN1CCn2c(nn(C)c2=O)C1)c1ccccc1Cl +Cc1ccsc1CNC(=O)NCCC(=O)NC(C)C +COC(=O)c1c(C)[nH]c(C(=O)NC(C)(C)c2nc(C)c(C)s2)c1C +CC(CNC(=O)Cc1nn(C)c(=O)c2ccccc12)N1CCOCC1 +CCOc1ccc(NC(=O)CNCc2ccccc2)cc1 +Cn1nccc1CNC(=O)CCNC(=O)c1ccc(C(C)(C)C)cc1 +Cc1cc2c(=O)n(CC(=O)Nc3ccc(F)cc3)cnc2s1 +COc1ccc(Cl)cc1CNC(=O)CN1CCOCC1C +CC(C(=O)N1CC=C(c2cccc3ccccc23)CC1)n1cncn1 +CS(=O)(=O)c1ccc(Sc2ncc(N)cn2)cc1 +CCCn1c(C)cc(C(=O)Cn2nnc(-c3ccccc3C)n2)c1C +COc1ccc(C(=O)NCC2CC2C)c(OC)c1OC +CCc1ocnc1-c1nc(-c2ccc(CO)cc2)no1 +Cn1c(=O)c2sccc2n(CC(=O)Nc2ccccc2Cl)c1=O +CCc1nnc(NC(=O)CNc2ccc(C)cc2)s1 +Cc1nn(C)c(C(N)=O)c1NC(=O)c1nn(C)c2ccccc2c1=O +O=C(NCC1COCc2nc3cccnc3n21)c1ccc(F)cc1 +COc1cccc(C(=O)NCCC(=O)NCC2CCCO2)c1 +CN(CC(N)=O)C(=O)c1ccc(COc2ccccc2F)o1 +CCn1cc(S(=O)(=O)c2ccc(C)cc2)c(=O)c2cc(F)ccc21 +O=C(Nc1cccc(CS(=O)(=O)c2ccccc2)c1)C1CC1 +N#Cc1ccc(Oc2ccc(F)c(C#N)c2)c(F)c1 +Cc1ccc(C)c(-n2ccnc2S(=O)(=O)Cc2c(C)noc2C)c1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)NCc1ccncc1 +CCc1cc(N)cc2c(CC(=O)Nc3ncccc3C)noc12 +COc1cc(=O)c(C(=O)NC2CC2)nn1-c1ccc(C)cc1 +CCN(C(=O)c1ccc2c(c1)CCC(=O)N2C)C(C)C(C)C +COc1cc(Cl)ccc1C(=O)N1CCN(c2ccc(O)cc2)CC1 +O=C(CC1CCCCC1)OCC(=O)N1CCCC1 +CC(C)c1ccccc1-n1[nH]c(=O)c2ccccc2c1=O +CC(Sc1ccccc1O)C(=O)NC1CCCCC1 +COc1cccc(OC)c1C(=O)N1c2ccccc2CC1C +CCCC1CN(C(=O)Nc2ccc(F)c(NC(C)=O)c2)CCO1 +Cc1ccc(CN(Cc2ccco2)C(=O)c2cnccn2)s1 +CCOc1ccc(C(N)=O)c(OCC)c1OCC +N#CCC1CCCc2c1c(Cc1ccccc1)nn2CC#N +CCCC(C)C(=O)Nc1ccccc1S(C)(=O)=O +Cc1occc1C(=O)NC1CCCC1Cc1ccccc1 +CCOc1ccc(-c2nn(C(C)(C)C)cc2CO)cc1 +CNS(=O)(=O)c1ccc(OC)c(-c2nc(C(C)C)no2)c1 +Cc1cnn(CCNC(C(N)=O)c2ccc(Br)cc2)c1 +O=C(NC1CCCC1)c1ccc(NC(=O)c2cc3ccoc3cn2)cc1 +COCCn1cnnc1CN(C)C(=O)c1ccc2nc(C)cn2c1 +Cc1c(C(=O)NCC2COC3(CCC(C)CC3)O2)cnn1C +O=C(Nc1ccc(F)c(Cl)c1)Nc1cnccn1 +Cc1ccc(C2COCCN2CC2=CCCOC2)o1 +COc1ccc(C)cc1C(C)NC(=O)c1nc2nc(C)cc(C)n2n1 +COc1ccc(OC)c(CC(=O)NCCc2c(C)nn(C)c2C)c1 +CCC(CC)C(=O)Nc1nc2c(s1)CN(S(=O)(=O)CC)CC2 +CCn1nc(C(C)C)cc1C(=O)Nc1cc(F)ccc1OC +CC(=O)N1C=Cc2ccccc2C1CC(=O)Nc1ccn(C)n1 +Cc1cc(N2CCCC2C(=O)NC2CC2)ncc1Br +Cn1cccc1C(=O)NCc1cn(-c2ccccc2)nn1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)Nc1nnc(C2CC2)s1 +O=C(NCc1cccnc1-n1cccn1)c1ccncc1 +CCCCN1CC(C(=O)NCc2ccccc2Cl)CC1=O +COc1ccc(OCCc2nc(C)c(CCO)c(=O)[nH]2)cc1 +CC(NC(N)=O)C(=O)Nc1ccc(Oc2cccc(F)c2)cc1 +O=C(Nc1ccnc2[nH]ncc12)c1ccccc1-c1ccccc1 +Cc1cc(C)c(CNC(=O)NCCOc2ccccc2)c(=O)[nH]1 +N#Cc1cccnc1N1CCCC(S(=O)(=O)N2CCOCC2)C1 +COc1ccc(C(=O)CNc2c(C)cccc2C)cc1C +Cc1nc(C2CCCN2C(=O)c2cccc(OC3CCCC3)c2)no1 +CCc1nnc(NC(=O)c2cc3c(C)cc(C)cc3[nH]2)s1 +COc1ccc(OC)c(NC(=O)C(C)OC(=O)c2ccc(F)cc2)c1 +CC(NC(=O)c1cn(Cc2ccccc2)nn1)c1ccccc1F +O=C(NCc1ccc(O)cc1)c1scnc1C1CC1 +CCn1cc(C(=O)NCc2ccccn2)c(=O)c2ccc(C)nc21 +CCCn1nc(C(=O)NC2CCSc3ccccc32)ccc1=O +COCCCNC(=O)c1cc2c(Cl)ccc3c2n1CCO3 +Cc1ccc(-c2nnc(SC(C)c3nnc(C)o3)n2C)cc1 +Cn1ncc2c(N3CCCC3c3nc4ccccc4s3)ncnc21 +O=C(Cn1cnnn1)NC1(c2ccccc2)CCCC1 +Nc1cccc(-c2cn3c4c(sc3n2)CNCC4)c1 +CC(C)Cc1noc(CSc2nccn2C)n1 +CCNC(=O)c1cc(NC(C)c2ccco2)ccn1 +COc1ccc(CNc2ccn(Cc3ccccc3)n2)cc1O +CC(=O)N1CCC(NC(=O)N(C)CC2COc3ccccc3O2)CC1 +Cn1cc(Cl)cc1C(=O)N1CCC(C(O)c2ccccc2)CC1 +Cc1cc(C)cc(CN2CCN(Cc3cnc(N)nc3)CC2=O)c1 +Cc1cc(C(=O)NC(C)c2ccc(C)s2)on1 +CCCOC(=O)c1cc(-c2c(C)cc(O)cc2C)nn1C +N#Cc1cccc(NC(=O)c2ccc3c(c2)OCO3)c1 +CCCCNC(=O)c1noc(-c2ccc(C#N)cc2)n1 +CC(=O)c1ccc(NC(=O)CCNC(=O)OC(C)(C)C)cc1 +N#Cc1ncn(CC(=O)Nc2nc3c(s2)CCC3)n1 +CCNC(=O)c1cccc(NC(=O)c2cccc(OC)c2OC)c1 +COc1ccccc1NC(=O)CSc1c(C)n[nH]c1C +C#CCN1CCN(CC(=O)NCCc2ccc(OC)cc2)CC1 +Cc1cnc2nc(S(=O)CC(C)(C)C)sc2c1 +CCCCCC(=O)NCc1noc(-c2ccsc2)n1 +COc1cccc(CNC(=O)c2nc3nc(C)cc(C)n3n2)c1 +CCOc1cccc(OCCCC(=O)n2ccnc2)c1 +Cn1ccn2c(C(=O)Nc3cccc(F)c3)nnc12 +C=CCNC(=O)c1cccc(N2C(=O)C(C)(C)CS2(=O)=O)c1 +CCOC(=O)CNC(=O)C(N)c1ccc(F)cc1 +O=C(Cc1cn2ccsc2n1)N1CCCC(O)C1 +O=C(NCc1csc(=O)[nH]1)c1c[nH]nc1-c1ccccc1Cl +COc1ccc(-c2cn[nH]c(=O)c2CO)cc1Cl +COc1ccc(Cl)cc1N1CC(C(=O)NCCC(C)C)CC1=O +COc1ccc(OCCCn2cccc(C)c2=O)cc1 +CC1CCC(NC(=O)CN2CCN(C(=O)c3cccs3)CC2)CC1 +Cc1cc(NC(=O)CNc2ccc(F)cc2C)on1 +COc1ccc(C2NC(=O)c3oc4ccccc4c(=O)c32)cc1OC +NC(=O)c1cccc(NC(=O)c2ccccc2C(=O)c2ccccc2)c1 +CCOC(=O)CN(CC)C(=O)c1cc(C)ccc1OC +CCCS(=O)(=O)NCCn1ccc(C(F)(F)F)n1 +COc1ccc(N(C(=O)c2cccc(=O)n2C)C(C)C)cc1F +O=C(CS(=O)(=O)c1nccs1)NCC1CCCCC1 +O=C1NCCCCC1NC(=O)N1CCOC(c2ccc(F)cc2)C1 +N#Cc1cccc(OCC(=O)c2ccc3c(c2)CCC(=O)N3)c1 +Cc1cc(C(=O)Nc2ccc3nncn3c2)c(F)cc1F +CCCCOC(=O)C(C)N1C(=O)C(C)Oc2ccc(C(C)=O)cc21 +Cc1nc(C)c(C(=O)Nc2ccc(-c3cn4cccnc4n3)cc2)s1 +CCCn1cc(NC(=O)N2CCC3(C=Cc4ccccc43)CC2)nn1 +CC(C)(C)OC(=O)NC1CC(C)(C)c2ccc(N)cc21 +CC(C)(C)c1ccc(C(=O)C(C#N)c2ccccn2)cc1 +Cn1cccc1C1CCCCCN1C(=O)c1cccc2cn[nH]c12 +COC(=O)c1nnn(CC(=O)NC(C)c2ccccc2)c1N +Cc1n[nH]c(C)c1S(=O)(=O)N(C)Cc1ccco1 +CC(=O)Oc1cccc(C(=O)c2ccc(C#N)cc2)c1 +CCC(=O)N(CC1CCCO1)c1nc2c(C)cc(C)cc2s1 +CC(=O)Nc1cc(C(=O)NC2CCN(CC(F)(F)F)C2)ccc1C +CCC(C)NC(=O)Nc1ccc(C(=O)NC(C)CC)cc1C +O=C(NCCc1nc(-c2ccccc2)no1)c1ccc(F)cc1 +O=C(c1ccc[nH]c1=O)N1CCCC1c1ccccn1 +CCCCC(NC(N)=O)C(=O)NC1(C)Cc2ccccc2C1 +COCCN1CCN(c2nc(C)nc3c2cnn3C)CC1 +N#Cc1cccnc1NCC(O)c1cccc(F)c1 +COc1cccc(CNC(=O)C2CCN(C(=O)NC3CC3)CC2)c1 +COCCNC(=O)NCCn1c(C(F)(F)F)nc2ccccc21 +CCOc1ccc(C(=O)Nc2ccccc2N2CCC(O)CC2)cn1 +c1ccc(C2CCCN2Cc2cccc3nonc23)nc1 +CN(C)C(=O)Cc1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +Cc1cccc(NCC(=O)Nc2ccccc2F)c1C(N)=O +COC(=O)Cn1c(=O)nc2n1C(=O)N(c1ccccc1)C2 +COCCN(C)C(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +CCC(C)C(=O)N1CCC(Cc2nc3cccnc3n2CCOC)C1 +CCCc1cc(C(=O)NC(c2nc(C3CC3)no2)C(C)C)n(C)n1 +COc1ccccc1NC(=O)N(Cc1ccc(C)o1)CC1CCCO1 +CCCNC(=O)c1ccccc1NC(=O)c1cccc(OC(F)F)c1 +Cc1nn(C)c(C)c1CCOC(=O)c1ccc(-n2ccnn2)cc1 +Cc1ccc(-c2noc(C3CCN(C(=O)C4CCCCC4)CC3)n2)o1 +CC(C)NC(=O)c1cc2occc2n1Cc1cccc(F)c1 +COc1cc(C)cc(OC)c1OCC(=O)Nc1cccc(F)c1 +Cc1ncsc1CN1CCOCC1CC(C)C +Cc1noc(C)c1S(=O)(=O)N1CCC(Oc2ncccn2)CC1 +Cc1nn(-c2ccccc2)c(C)c1C(NCC(N)=O)C(F)(F)F +O=c1n(Cc2nccn2CC(F)(F)F)nnn1-c1cccs1 +CCS(=O)(=O)c1ccc(C(=O)N2CCCCC2c2ccco2)cc1 +Cc1ccc(CSc2nnc(-c3[nH]nc4c3CCC4)n2N)cc1 +Cc1ccc2nc(SCC(=O)N(C)c3ccccc3)nc(=O)n2c1 +CCCn1cnnc1C1CCN(C(=O)Cc2ccc(Cl)cc2)CC1 +Cc1cc(C)nc(SCC(=O)Nc2ccc(C(=O)N(C)C)cc2)n1 +CS(=O)(=O)c1nc2ncc(Br)cc2s1 +COc1cc(C(=O)n2c(C)nc3ccccc32)cc(OC)c1OC +CC(CO)NC(=O)c1cccc(S(=O)(=O)NC2CCCC2)c1 +N#CCCc1c(C(F)(F)F)nc2ncccc2c1Cl +O=C(CCOCC(F)(F)F)NC1CCCCC1 +Cc1[nH]c2c(OC(C)C)cccc2c(=O)c1CCC#N +CC(C)CC(=O)NC(C)c1ccccc1NS(C)(=O)=O +Cc1ccc(=O)n(CC(=O)NCc2ccc(-c3ccc(O)cc3)cc2)n1 +CCc1ccsc1C(=O)N(CCO)C(CC)CC +Cc1oc(S(N)(=O)=O)cc1C(=O)NCc1oc2ccccc2c1C +Cc1ccccc1CNC(=O)COc1ccccc1C +CNC(=O)COC(=O)c1cccc(OCc2cccc(Cl)c2)c1 +CCOc1ccccc1-c1nc(CN2CCN(C(C)=O)CC2)c(C)o1 +OC(c1ccccc1)C(c1cccnc1)n1nnc2ccccc21 +O=C(c1cccs1)N1CCOC(c2nc(-c3ccccc3)no2)C1 +CC(OCc1ccccc1)C(=O)Nc1ccc(C#N)c(Cl)c1 +COC(=O)c1ccccc1Cn1ccnc1Cc1ccccc1 +O=C(Nc1cc(F)cc(F)c1)N1CCc2[nH]nc(C(F)(F)F)c2C1 +O=C(Nc1ccc(NC(=O)c2cccs2)cc1)c1cnccn1 +Cc1noc(C(C)C)c1C(=O)N1CCCC(c2ccn[nH]2)C1 +CCc1cnc(NCC2CC(=O)N(CCOC)C2)nc1 +CCCC1(CO)CCCN(C(=O)c2cc(-c3ccsc3)n[nH]2)C1 +CCc1ncc2c(n1)CN(C(=O)C(C)(C)NC(=O)c1cccs1)C2 +COc1ccc(C(=O)NC(C)(C#N)C(C)C)cc1OC +CC1CCCCC1NC(=O)CN1CCCS1(=O)=O +CC(C)CC(=O)NCc1ccccc1-n1cccn1 +Cc1cc(C)c(C(=O)Nc2ccc(C(N)=O)nc2)c(C)c1 +O=S(=O)(c1ccc(Br)cc1)C1CCCC1 +O=C(CCc1ccncc1)Nc1ccc(NC(=O)C2CC2)nc1 +Cc1c(C2Nc3ccccc3C(=O)N2CC(F)(F)F)cc(C#N)n1C +CCCC(=O)Nc1ccc(Br)c(C)n1 +CCC(C(=O)NC1(C(N)=O)CCCC1)n1cccn1 +CCC(NC(=O)c1ccc(COC)o1)c1cccc(Cl)c1 +Cc1cc(C)n(C(=O)c2ccnc3ccc(Br)cc23)n1 +CC(Nc1cnn(C(C)(C)C)c1)C(=O)Nc1ccc(F)cc1F +CCOCCCCNC(=O)Nc1ccc(C#N)c(Cl)c1 +Cc1oc2nc(C3CC3)n(Cc3ccccc3)c2c1N +COc1ccc(C)cc1NC(=O)c1c(Cl)c(C)nn1C +CCCN(CCO)C(=O)Nc1ccc(F)c(Cl)c1 +CN(C)S(=O)(=O)N1CCC(Oc2cnccn2)CC1 +CCCC(=O)Nc1nc(CN2CC(C)OC(C)C2)cs1 +N#Cc1ccc(Cl)cc1NCc1ccc2c(c1)OCCCO2 +COc1ccc(OC)c(NCc2ccc(F)c(F)c2)c1 +COCCCNC(=O)c1oc2ccc(Br)cc2c1C +Cc1c(N)c[nH]c(=O)c1C(=O)N(C)Cc1ccccc1 +O=C(Cc1ccc(N2CCCC2=O)cc1)Nc1cccc(Cl)c1 +CCC(C)NS(=O)(=O)c1ccc(C(F)F)cc1 +CCc1sc(C(=O)N2CCCC(c3nncn3C)C2)cc1C +CC(O)(CNS(=O)(=O)c1ccc(Br)cc1)C1CC1 +Cc1ccc(C(=O)N2CCOC3C(Oc4cccnc4)CCC32)cn1 +CN(C)S(=O)(=O)c1cccc(NC(=O)CCCn2cncn2)c1 +CCc1ccc(C(C)NC(=O)C(C)N2CCCC(NC(C)=O)C2)cc1 +O=C(NC1CCCc2occc21)c1c(Cl)ccc(Cl)c1Cl +Cc1cc(C)n(CC(=O)NCC2CCOc3ccccc3C2)c(=O)n1 +COc1ccc(-c2nc3c(n2O)CCCC3=O)cc1OC +O=C(Cc1csc(-c2nc[nH]n2)n1)NC1CCCc2occc21 +COc1ccc(-c2ccn(CC(=O)Nc3cc(C)nn3C)n2)c(F)c1 +CC(C)N(Cc1ccccc1)C(=O)c1cncc2cnccc12 +Nc1cn2c(-c3ccc(F)c(F)c3)csc2n1 +CNc1ncc(C(=O)Nc2n[nH]c(Cc3cccc(F)c3)n2)s1 +O=S(=O)(Cc1cccc(F)c1)NCC#Cc1ccccc1F +CC1CN(c2ccc(Nc3ncnc4c3cnn4C)cn2)CC(C)O1 +CS(=O)(=O)N1CCC(c2nnc(C3CC3)s2)CC1 +CSc1ccc(C2CC(=O)Nc3c2c(C)nn3-c2ccccc2)cc1 +C#CCN1CCC(C(=O)N2CCCC2CCc2ccccc2)CC1 +O=C(NCc1ccoc1)Nc1ccc(F)c(F)c1 +Cc1ccoc1C(=O)Nc1cccc(C(=O)NC2CC2)c1 +CCOc1cccc(NC(=O)C2CCC(=O)NC2)c1 +COc1ccc(OCc2nc(C(=O)NC(C)C)cs2)cc1 +COC(=O)c1ccc(F)c(NCc2cnc(C)s2)c1 +CCc1cccc(CC)c1NC(=O)C1CCCN(S(C)(=O)=O)C1 +Cc1csc(C(C#N)C(=O)CCc2ccc(C#N)cc2)n1 +O=c1[nH]c2cc(Cl)c(C(O)C3CCCO3)cc2[nH]1 +N#CC1CC(=O)N(c2cc(Cl)c(Cl)cc2Cl)C1 +O=c1oc(-c2ccc(F)cc2)nn1CCc1ccccn1 +O=C(CNC(=O)c1n[nH]c2ccccc12)Nc1ccc(F)c(F)c1F +CC1CN(CCc2nc(-c3ccccc3N)cs2)CC(C)O1 +CCOc1ccc(NC(=O)C2CC(=O)N(CCOC)C2)c(C)c1 +O=C1CN=CN=CN1c1ccc(Cl)cc1Cl +N#Cc1ccnc(C=Cc2cn(-c3ccc(F)cc3Cl)nn2)n1 +Cc1csc(NC(=O)c2ccc(O)c(Cl)c2)n1 +O=C(c1ccc(CSc2ncc3ccccn23)cc1)N1CCCC1 +COc1ccccc1N1CCC(CNC(=O)COC2CCCC2)C1 +CC(C)c1nc2ccc(NC(=O)NCc3ccco3)cc2s1 +COC(=O)CC(C(=O)c1cc(C)ccc1C)N1CCOCC1 +CCCC1CN(C(=O)c2cc(=O)n(-c3ccc(C)cc3)[nH]2)CCO1 +O=C(NCCCOc1ccc2c(c1)OCO2)c1ccc2cncn2c1 +COc1ccc(Cc2nc3ccc(OC)cc3c(=O)[nH]2)cc1 +CC(CC(=O)Nc1cccnc1-n1cccn1)c1ccccc1 +COCc1nn2c(nnc3c(O)cccc32)c1-c1ccccc1 +Cc1ccc(OC(C)C(=O)Nc2ccccc2N)c(C)c1 +CC(=O)NCC(=O)Nc1ccc(C)cc1Br +COC(=O)c1cc2c(Br)cncc2s1 +CC(O)c1cc(F)ccc1Oc1ccc(C#N)cc1 +COc1ccccc1C1(CNC(=O)c2ccoc2)CCCC1 +CCc1nc2ccccc2c(=O)n1CC(=O)N1CCCC1 +Cc1ncn(CC(=O)Nc2ccc(F)cc2F)c(=O)c1C +Cc1cc2c(=O)n(Cc3ccc(F)cc3F)cnc2s1 +Cc1nc(SCCO)c2c3c(sc2n1)CCC3 +Cc1ccc(CN(C)C(=O)Nc2ccc(F)cc2F)s1 +CC(=O)N1CCCC(c2nc(C)ncc2-c2cc(C)no2)C1 +O=c1n(Cc2cc(-c3ccc(Cl)cc3)no2)nc2ccccn12 +CCc1nnsc1C(=O)NCC(O)c1ccccc1C(F)(F)F +CCc1ccccc1NC(=O)CNC(=O)Cn1ccnc1 +NC(=O)CSc1nnc(-c2cccnc2)n1CCCO +O=S1(=O)N=C(NCc2ccc(-n3cncn3)cc2)c2ccccc21 +CC(C)(C)c1nc(CC(=O)NC(C#N)c2ccsc2)cs1 +Cc1ccoc1C(=O)N1CCC(C2CCN(c3ncccn3)CC2)C1 +CCOc1cccc(CNC(=O)C2COc3ccccc3C2)c1 +O=C(NCc1ccccc1)c1cc2occc2n1-c1ccccc1 +c1nc2c(c(N3CCCC(Cn4cncn4)C3)n1)CCC2 +CCCS(=O)(=O)N1CC2CCN(CC3CC3)C(=O)C2C1 +CCN(CC)C(=O)Cn1c(CN2CCOCC2)nc2ccccc21 +O=C(CCc1ccccc1)NCc1noc(C2CCCC2)n1 +O=c1[nH]ncc(NCCc2c[nH]c3ccccc23)c1Cl +CCNC(=O)c1cnc(-c2ccccc2OC(C)C)nc1N +Cc1cccc2c(CCC(=O)n3ncc(C#N)c3N)c[nH]c12 +CNC(=O)c1cc(Cl)ccc1NCc1nsc(N(C)C)n1 +COc1c(Cl)ccc2c1C(c1cc[nH]n1)NCC2 +O=C(Cc1cccn1-c1ccc(F)cc1)NCCN1CCOCC1 +O=C(c1ccncc1)N1CCC(c2cc3ncccc3c(=O)[nH]2)CC1 +COc1cc(CNC(=O)c2ccco2)ccc1OCC(F)(F)F +CC(NC(N)=O)C(=O)N(C)Cc1ccc(SC(F)F)cc1 +COc1ccc(OC)c(NC(=O)C(C)Oc2ccccc2C#N)c1 +Cc1ccn2cc(C(=O)OC(C)c3nc4ccccc4c(=O)[nH]3)nc2c1 +CC(C)CCOC1C(C2COC(C)(C)O2)OC2OC(C)(C)OC21 +COCC(C)C(=O)Nc1ccc(CN2CCOCC2)c(Cl)c1 +O=C(NC1CCC(O)CC1)N(CC1CCOC1)C1CC1 +CC(C)CCC(=O)NCC(=O)NC1c2ccccc2CC1O +O=C(COc1ccc(-n2cnnn2)cc1)N1CCOC2CCCCC21 +Fc1cc2c(c(F)c1F)C(c1ccncc1Cl)NCC2 +COC(=O)c1ccccc1Oc1cc(=O)n(C)c(=O)n1C +N#Cc1cccc(NC(=O)Nc2cnn(-c3ccccn3)c2)c1 +CCC1CCCN(C(=O)C2CC(=O)N(C(C)C)C2)C1 +Cc1ccc(-c2nccn2-c2ccc[nH]c2=O)c2cccnc12 +O=C(c1nccn2ccnc12)N(CCc1cccc(F)c1)C1CC1 +COCCNC(=O)C1CC(=O)N(c2n[nH]c3ccccc23)C1 +CCn1nc(C)c2c1cnn2CCNC(=O)c1cc(C)n(C)n1 +O=S(=O)(c1cccnc1)N1CCCC1C1CCCCC1 +Cc1cc(C)cc(OCCC(=O)NCCc2cscn2)c1 +COc1ccc(C(=O)C2CCCN2C(=O)C(C)(C)C)cc1 +O=c1cc(Cn2ncc(Cl)c(Cl)c2=O)[nH]c(=O)[nH]1 +CCCCn1nc(C(=O)Nc2cc(Cl)ccc2F)ccc1=O +Cc1csc(N(CC(F)(F)F)C(=O)CCOc2ccccc2)n1 +COc1ccc(CNC(=O)C(C)OC(C)C)c(F)c1F +CCOC(=O)c1cc(C(C)(C)C)oc1CNC(N)=O +Cc1cccc2c1NC(c1ccc(O)cc1)NC2=O +COc1cccc(C2(C(=O)N3CCN(C)CC3)CC2)c1 +CCSc1ncc(Cl)c(C(=O)Nc2nnc(CC)s2)n1 +CCn1nc(C(C)C)cc(C(N)c2ccccc2)c1=O +Cc1csc(=O)n1CCN1CCc2cc(Br)ccc21 +CCOC(=O)c1ccc(NCC(=O)N2CC(C)OC(C)C2)cc1 +COC(=O)c1cnn2c(C)c(Cc3ccccc3)c(C)nc12 +O=c1[nH]nc(SCC(O)CO)n1CCc1ccccc1 +CCCC(=O)Nc1cccc(C(=O)Nc2nc(C)cs2)c1 +Cc1nn2cc(C(=O)Nc3ccc(C(C)(C)C)cc3)nc2s1 +CCC(NCCc1nnc2n1CCCCC2)c1ccc2c(c1)CCO2 +Cc1cc(C)n(CCN2CCN(C(=O)Cn3cccn3)CC2)n1 +COC(=O)c1ccc(S(=O)(=O)NCc2ccccn2)c(Cl)c1 +CC(C)c1nnc(CNC(=O)c2cccc3[nH]ccc23)n1C +Cc1cccc(C(=O)Nc2nnc(-c3cccnc3)o2)c1 +O=C(NCC1CCOC1)c1cc(-c2ccc(Cl)cc2)n[nH]1 +Cc1cc(C)n(CC(=O)NC(C)c2ccc3c(c2)NC(=O)CO3)n1 +O=C(NCCc1nc[nH]n1)c1c[nH]nc1-c1ccccc1F +Cc1cc(NC(=O)C2CN(C(=O)COc3ccccc3F)C2)no1 +Cc1ccc(N2CCc3c(CNC(=O)c4ccco4)cncc3C2)nn1 +Cc1cccc(-n2ncc(C(=O)N3CCCCC3C)c2-n2cccc2)c1 +CCCC(O)c1ccc2c(c1)C(NC(=O)COC)CCC2 +COC(=O)C1(C(O)c2ccccc2O)CCCCC1 +COCC1CCCN1C(=O)Cn1cccnc1=O +NC(=O)c1cn(-c2ccccc2)nc1-c1ccc(Cl)cc1 +CCCS(=O)(=O)NC(C)c1ccc(OC)c(Br)c1 +O=C(CCc1cccnc1)NCc1cc(Cl)c2c(c1)OCCCO2 +C=CCNC(=O)c1ccc(NC(=O)CNC(=O)CC)cc1 +CC(=O)Nc1ccccc1C(=O)Nc1ccc(C(N)=O)cc1 +COc1ccccc1Oc1ccc(F)cc1C(C)=O +CCN(C)C(C(=O)NCCc1csc(C)n1)c1ccccc1 +CC(C)(C)OC(=O)NC1(CNS(C)(=O)=O)CCCCC1 +CC1=C(C(=O)NCc2ccc(-n3cncn3)cc2)C(C)NC(=O)N1 +CC1CCC(NC(=O)CNC(=O)c2ccccc2)CC1 +CN(CCc1ccccn1)C(=O)c1cncn1-c1ccccc1 +COCC(=O)Nc1ccccc1N1CCc2ccccc2C1 +CC(C)(C)c1csc(CNC(=O)c2cccc(-n3cccn3)n2)n1 +Cc1cc(=O)[nH]c(-c2cccc(NC(=O)c3ccc4c(c3)CCC4)c2)n1 +CCOC(=O)CCNC(=O)Nc1cc(C)ccc1OC +CCOC(=O)CN(C)C(=O)c1cc(N)cnc1C +CCCN(CC1CCCCC1)C(=O)c1nccnc1N +Cc1cc2ccccc2n1CCC(=O)N1CCCC1Cn1cccn1 +COc1cccc(NC(=O)CN(Cc2ccon2)c2ccccc2)c1 +C(=Cc1ccco1)CNc1ccccc1CN1CCOCC1 +COc1ccc(CNC(=O)N2CC(C)OC(C)C2)cc1F +COc1ccc(NC(=O)c2scnc2C2CC2)c(C)n1 +CCCCn1nnnc1CN1CCc2cnc(CC)nc2C1 +COc1ccc(-c2nc(CNC(=O)C(C)(C)C)no2)cc1 +COC(=O)CCC(=O)Nc1ccc(S(C)(=O)=O)nc1 +O=C(COC(=O)c1ccc(O)cc1)c1ccc2c(c1)OCCO2 +CC1CCN(S(=O)(=O)c2ccccc2Br)CC1 +O=C(Nc1cccc2cn[nH]c12)c1csc(-c2ncccn2)n1 +O=C(Cc1cccs1)NCc1cc(-c2ccc3c(c2)OCO3)on1 +COC(=O)c1cccc(NC(=O)N2CCC(CO)CC2)c1 +COc1ccc(C(=O)c2ccc(O)c(C)c2)cc1OC +O=C(NCc1ccc2c(c1)OCCO2)c1cccc(OC(F)F)c1 +CN(Cc1ccc(OC(F)F)cc1)C(=O)CCc1cccnc1 +CCc1cnc(C)nc1N1CC=C(n2c(=O)[nH]c3ccccc32)CC1 +COCCCC(=O)Nc1cc(Cl)ccc1-n1cccn1 +CC(C)Sc1ccc(-c2nnc(NC(=O)C(C)C)o2)cc1 +CC(C)COC(C)C(=O)NCc1ccccc1F +CNS(=O)(=O)c1ccc(C(=O)N(C)CC2CC2)o1 +CN(CCc1ccccc1)C(=O)CCc1cnn(C)c1 +Cc1cc(NC(=O)CCSc2ncccc2Cl)no1 +CCCCCCC(=O)N1CCCC(c2nc(C)no2)C1 +COc1coc(C(=O)N2CCCC(O)(CO)C2)cc1=O +CCC1C(=O)NCCN1Cc1cc(F)ccc1Br +Cc1cc(C(=O)NCC2CCN(c3cnccn3)CC2)c(C)o1 +CN(C(=O)Cn1cnc2ccccc2c1=O)c1ccc2ccccc2c1 +Cc1cc(OCC(=O)NCc2cn3ccsc3n2)ccc1Cl +CCN(CC)C(=O)c1ccc(NC(=O)c2cc(C(N)=O)cn2C)cc1 +CNc1nc(C(N)=O)c(NC(=O)c2ccccc2C)s1 +Cc1cccnc1C(NC(=O)N1CCCC(CC(N)=O)C1)C(C)C +COc1ccc(CC(=O)Nc2cc(Cl)ccc2N)cc1 +COc1ccc(CNc2ncnc(NC(C)c3ccccc3)c2N)cc1 +COc1ccccc1C1(CNCc2c[nH]nc2C)CCCC1 +CCc1ncc(CN(C)C(=O)c2ccccc2C(C)=O)s1 +CCn1nc(C(=O)Nc2ccc(F)cc2F)cc1C +CC(C)CNC(=O)N1CCC(C(=O)c2ccc(O)cc2)CC1 +Cc1cc(NCC2CCCO2)cc(=O)n1Cc1ccco1 +N#CCCCn1c(-c2cccs2)nc2cc(Cl)cnc21 +O=C(CN1C(=O)C2=C(CCC2)Nc2ccccc21)Nc1ccccc1 +CS(=O)(=O)N1CC(C(=O)NCc2cccnc2)C1 +O=C(Nc1nc(-c2ccc(F)cc2)ns1)c1ccco1 +COc1cc(C(=O)NCC(C)c2ccccc2)cc(OC)c1OC +O=C(Nc1ccc(Cc2nc3ccccc3[nH]2)cc1)c1cccnc1 +CCC(NC(=O)CN1CCOCC1C1CC1)c1ccc(Cl)cc1 +CC1(CNC(=O)N2CCOCC2C2CC2)CCCO1 +Cc1cc(C(=O)Nc2cc(C)n(C)n2)c2c(C)noc2n1 +COC(=O)c1cc(-c2cc(F)ccc2F)[nH]c1N +N#CC(CCC(=O)Nc1ccccc1F)c1cccnc1 +CCC(C)n1nccc1NC(=O)c1cccc(OC)c1F +CC(C)c1ccsc1C(=O)N1CCN(C2CCCC2O)CC1 +COc1cc(C(=O)Nc2ccc(Cl)cc2)cc(OC)c1OC +CCC(=O)N(Cc1cccs1)C1CCOC(C)(C)C1 +CC(=O)Nc1ccc(F)c(C(=O)OCCOc2ccccc2)c1 +Cc1cc(C)c(CNC(=O)NC(C)COc2ccccc2)c(=O)[nH]1 +O=S(=O)(Nc1ccc(OC(F)F)cc1)c1ccc(F)cc1 +Cc1ccc(-n2nnnc2Cc2ccccc2F)cc1 +O=C(Nc1ccccc1OC(F)F)c1csnn1 +COCc1ccccc1NC(=O)N1CCN(Cc2ccccn2)CC1 +CCc1nc(CNc2cc(OC)ccc2OC(C)C)cs1 +O=C(c1cc(Cl)ccc1O)N1CCCCC1CCO +COc1ccc2cc3cc(C(=O)NC(C)C)oc3nc2c1 +CC(CNC(=O)Nc1cccc(N2CCNC2=O)c1)c1ccccc1 +CN(C)c1ccc(C(=O)Nc2ccc3c(c2)CC(=O)N3C)cc1 +COc1cccc(-c2cnnc(N(C)Cc3ccncn3)n2)c1 +CCOC(=O)CNC(=O)CC1CSc2nc(C(C)C)cc(=O)n21 +O=C(CSc1ccc(-c2ccncc2)nn1)N1CCCCCC1 +CC(C)c1nc(CC(=O)NCCOc2cccnc2)cs1 +CC(Oc1ccc2c(c1)CCCC2)C(=O)N1CCC(O)CC1 +CNc1snc(C)c1C(=O)OCC(=O)C(C)(C)C +Cc1nc(CN2CCc3ccc(S(N)(=O)=O)cc32)cs1 +CC(C)c1nc(COc2cccc3cccnc23)cs1 +O=c1c(N2CCOCC2)csc2ccc(F)cc12 +Cc1ccc(CC(=O)NC2CCN(c3c(F)cccc3F)C2)cn1 +CC1(C)COCCN1C(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CS(=O)(=O)N1CC2COCC2(CC(=O)NCc2cccs2)C1 +Cc1csc(N2CCN(C(=O)c3c(C)nn4cccnc34)CC2)n1 +CC1(C)Cc2occc2C(NC(=O)Nc2ccc(Cl)cc2)C1 +CCc1onc(C)c1C(=O)N1CCN(C(=O)CC(F)(F)F)CC1 +Cc1cccc(CNC(=O)c2cc3sccc3n2C)c1 +Cc1cn2nc(NCc3nc(-c4ccc(F)cc4)c[nH]3)sc2n1 +COC(=O)c1cccc(CCNC(=O)c2cccc3[nH]ccc23)c1 +CN(CC(=O)N1CCCC1c1ccccc1)S(C)(=O)=O +O=C(c1ccccc1)N1CC2CCC(C1)N(Cc1cnc[nH]1)C2 +NC(=O)C1CN(Cc2cccc3c2OCCCO3)CCO1 +CCN(Cc1cc2cc(OC)ccc2[nH]c1=O)C(=O)c1ccco1 +CCOc1cc(C(=O)Nc2cnn(CC(F)(F)F)c2)[nH]n1 +CC(C)C(NC(=O)NCC(C1CC1)C1CC1)c1nnc2ccccn12 +N#Cc1cccc(Cn2ccnc2Cc2ccc3ccccc3n2)c1 +Cc1ccccc1Cn1c(C(C)C)ccc(C#N)c1=O +COCCN(C(=O)c1c(F)ccc(C)c1F)C(C)C(N)=O +COCCCC(=O)N1CC=C(c2ccccc2Cl)CC1 +Cc1nn(CC(O)COc2ccccc2)c(=O)c2ccccc12 +Cc1ccccc1NC(=O)c1ccc(Cl)cc1N +CNC(=O)c1cccc(NCC(=O)NCc2ccc(Cl)cc2)c1C +O=C(Nc1c(F)cccc1F)NC1CCN(c2ccccc2)C1=O +OCc1ccc(-c2nccn2CCc2nc3c(s2)CCCC3)o1 +C=CCn1c(C)nnc1SCC(=O)Nc1ccc(C)cc1C +Nc1ccc(OCC(=O)NC2CCOCC2)c(F)c1 +O=C(NCc1nnc2n1CCCCC2)c1ccccc1C(F)(F)F +CC(C)N(C(=O)CSc1nnc2n1CCCCC2)C1CCCC1 +CC(=O)N(C)Cc1cccc(NCc2cccc(Cl)c2)c1 +CCC(Oc1ccccc1OC)C(=O)NCc1ccncc1 +Cn1ncc2c1CCCC2NC(=O)COCC1CC1 +CCOc1ccc(S(=O)(=O)Nc2cccnc2)c2ccccc12 +Cn1cc(C(=O)Nc2ccc(-c3nnc4n3CCCCC4)cc2)cn1 +Cn1cccc1C(O)CNC(=O)NCc1cccs1 +CC(=O)c1ccc(NC(=O)c2csc(-c3cnn(C)c3)n2)cc1C +CC(C)(C)N(Cc1ccccc1)C(=O)COc1nncc2ccccc12 +CC(=O)Nc1cc(C(=O)N2CCCC(C(F)(F)F)C2)ccc1F +CC(C)(C)NC(=O)c1cccc(NCC(=O)N2CCCCCC2)c1 +CC(C)N(C(=O)c1cccc(N(C)C)c1)C1CCC1 +COc1cc(OC)cc(C(=O)N2CCc3cc(N)ccc32)c1 +CCN(CC)S(=O)(=O)c1ccc(Cl)cc1N +CCc1noc(-c2ccc(NC(=O)c3cccc(OC)c3)cc2)n1 +CC(C)S(=O)(=O)c1ccc(C(=O)CC(C)(C)C)cc1 +CC(Sc1nncn1-c1ccccc1F)C(=O)Nc1ccccc1 +Cc1cc(C)c(Br)c(C(=O)NC2CCN(C(N)=O)C2)c1 +CN(c1ccc(C(=O)NC2CC2)c(Cl)c1)S(C)(=O)=O +CNS(=O)(=O)C1CCCN(C(=O)c2cc(F)c(C)cc2F)C1 +Cc1cc(C(=O)CNC(=O)NCCc2cccs2)c(C)[nH]1 +CCn1cc(NC(=O)c2cn(-c3ccc(Cl)cc3)nc2C)cn1 +N#CCc1ccc(NS(=O)(=O)c2ccc3c(c2)CCC3)cc1 +CN1CCN(C(=O)Cn2ccc(C(F)(F)F)n2)CC1 +CC(NC(=O)Nc1ccc(F)cc1F)c1cnn(C)c1 +CC(NC(=O)C(C)(C)C)C(=O)NC(C)c1ccc(-n2cncn2)cc1 +CSc1ccc(NC(=O)c2ccc(-n3cccc3)nc2)cn1 +CC(=O)Nc1ccc(OC(=O)c2sc3ccc(F)cc3c2C)cc1 +Cc1cnn(CCC(=O)Nc2cc(C#N)ccc2Cl)c1 +O=S(=O)(Cc1ccc(F)cc1F)N1CCOc2cccc(F)c21 +CC(C)CN(CC(F)(F)F)C(=O)Nc1cccnc1 +CN(CC1CCCO1)C(=O)c1c[nH]nc1-c1ccccc1 +N#Cc1ccc(N2C(=O)c3ccccc3S2(=O)=O)cc1 +CCc1ccc(CCNC(=O)NCc2cccc(OC)n2)cc1 +CCCN(c1cccnc1)S(=O)(=O)c1cncc(Cl)c1 +CCCNC(=O)Nc1cc(NC(=O)CC)ccc1C +CCn1cnnc1CNC(=O)c1cc(C)nc2cc(F)ccc12 +COc1ccc(-c2nnn(-c3cccc(OC)c3)c2N)cc1 +CC(=O)NC(C(=O)Nc1cc(C)cc(C)c1)C(C)C +Cc1ccc(CNC(=O)Nc2ccncc2)c(OCC2CC2)c1 +CCOC(=O)CN(C)C(=O)CCc1ccc(F)cc1 +CCOCc1ccc(CNC(=O)Nc2ccc(C(C)=O)c(C)c2)cc1 +Cn1c(=O)n(C2CCN(C(=O)Cc3ccsc3)C2)c2ncncc21 +O=C1c2c(O)cc(O)cc2OC(c2ccc(O)cc2)C1O +COC(=O)C1CCCN1C(=O)Nc1cccc(C)c1 +Cc1noc(-c2cccs2)c1C(=O)N(C)Cc1ccccc1 +Cc1cnc(NC(=O)COc2ccc(C#N)cc2)s1 +N#Cc1ccc(S(=O)(=O)NCc2cscn2)cc1 +COc1cccc(C2CSc3nnc(C(C)C)n3N2)c1 +N#Cc1cnn(-c2cccc(C(=O)NC3CCc4ccccc43)c2)c1N +Nc1nc(-c2ccccc2)ccc1C(=O)N1CCCC1 +CSc1c(C#N)c(NC(=O)C2CCCO2)nn1-c1ccccc1 +CC(C1CC1)N(C(=O)Nc1cccc2c1OCCO2)C1CC1 +CC(=O)Nc1cc(C(=O)Nc2cn[nH]c2)ccc1F +COC(=O)c1ccsc1NC(=O)C1CC1c1ccccc1F +COCCN(Cc1ccco1)C(=O)NCc1ccc(C)cc1 +COc1ccc(C(C)S(=O)(=O)c2ccc(C)cc2)cc1OC +O=C(NC1CC1)c1ccc(NC(=O)C(O)c2ccccc2)cc1 +N#Cc1c(N2CCCC2)nsc1NCc1ccccc1 +COc1ccc(C)cc1C(C)NC(=O)c1ccc(=O)n(C)n1 +CCCC(=O)Nc1c(C(=O)OCC)[nH]c2ccccc12 +O=C(NCc1ccco1)C1C=CCN1C(=O)Nc1ccccc1Cl +Cn1c(SCC(=O)NCC(F)(F)F)nc2ccccc2c1=O +Cc1cc(COC(=O)c2cn(C)c3ccccc23)no1 +C#CCn1cc(CN(C)C(=O)Cc2cccc3ccc(OC)cc23)cn1 +CCOC(=O)CCCNC(=O)Nc1nc(C)cs1 +CCn1c(SCC(=O)N(C)C)nc2sc3c(c2c1=O)CCC3 +Cn1cnc(S(=O)(=O)N2CCCC(C)(c3ccccc3)C2)c1 +CN(CC(=O)N(CC(F)F)c1cccc(Cl)c1)S(C)(=O)=O +O=C(Cc1cccs1)N1CCN(c2cnn3cnnc3c2)CC1 +COc1ccc2cc(C(=O)NCc3cnc(C)cn3)n(C)c2c1 +CCOC(CC)C(=O)N1CCC(C(=O)Nc2ccc(C)cn2)CC1 +COc1ccc(C(=O)Nc2cccc(Cl)c2C)cc1N +Cc1ccc(S(=O)(=O)C2(C(=O)Nc3cccc(F)c3)CC2)cc1 +CC(=O)Nc1cccc(NCC(=O)N(C)C(C)c2ccc(F)cc2)c1 +CC1CCCN(C(=O)C2CCN(C(=O)NCc3ccncc3)CC2)C1 +CC(=O)c1ccc(NC(=O)C2CCN(C(=O)C(C)(C)C)CC2)cc1 +CCN(Cc1nc2c(cnn2C)c(=O)[nH]1)Cc1ccc(C#N)cc1F +CC(C)N1CCN(C(=O)c2ccc(-n3ccnc3)nc2)CC1 +O=C(Cc1ccsc1)Nc1cnc(-c2cccnc2)nc1 +COc1cc(C)sc1C(=O)N(C)CC(=O)Nc1ccc(C)cn1 +COCCc1nnc2sc(-c3ccc(N(C)C)cc3)nn12 +Cc1ccc(NC(=O)C(C)Oc2ccccc2)c(O)c1 +COC(=O)C(NCc1ccc(C)s1)C(C)(C)C +O=C(CC(F)(F)F)NCc1ccc(Oc2ccccc2)nc1 +CC(=O)c1cccc(S(=O)(=O)N(C)C(C)C)c1 +O=C(Nc1ccc(C(=O)NC2CC2)cc1)c1ccc(=O)[nH]c1 +COc1ccc(CCNCc2ccco2)cc1OC +O=C1COc2ccc(C(O)CCN3CCOCC3)cc2N1 +COc1ccc2c(c1)OCC(C(=O)N1CCC(CC(N)=O)CC1)C2 +COc1cc[nH]c(=NS(=O)(=O)c2cccc(Cl)c2F)c1 +Cn1c(N2CCOCC2)nnc1S(=O)(=O)CCc1ccccc1 +O=C(CCc1ccco1)Nc1ccc2c(c1)OCCCO2 +COc1cccc(NC(=O)CN(C)C(=O)c2cccn2C)c1 +COc1cc(CNc2ccc(F)cc2F)cc(OC)c1O +Cc1cccc(C(C)(C)CNC(=O)C2CCCN(C(N)=O)C2)c1 +NC(=O)Nc1cccc(C(=O)NCc2ccc(Cn3cccn3)cc2)c1 +CCc1ccc(C(C)NS(=O)(=O)c2c(C)noc2C)cc1 +CN1CCN2CCN(C(=O)c3csc4c3CCCC4)CC2C1=O +COCCn1cc(CC(=O)Nc2nc(C)c(C)s2)c2ccccc21 +CCCCc1nnc(NC(=O)NC2CCCn3nc(CC)nc32)s1 +CCC(=O)NC(c1ccc2c(c1)OCCO2)C(C)C +CCCn1cc(-c2ccncc2)cc1C(=O)NCc1ccncc1 +CCOCC(=O)N1CCc2cn(CCOC)c3cccc(c23)C1 +CCc1ccc(C(NC(=O)N2CCCC(NC(C)=O)C2)C(C)(C)C)o1 +COC(=O)c1c(C)nn2c1ncc1c(=O)n(CC3CCCO3)ccc12 +COC(C)(C)c1noc(CCc2nc(-c3ccoc3)no2)n1 +Cc1ccccc1N1CCN(c2ccncn2)C(C)C1 +C=CCN(C(=O)c1cccc(C#N)c1)c1ccccc1 +CC(C)NC(=O)c1cccc(NC(=O)OC(C)(C)C)c1 +CCOc1c(Cl)cc(C(=O)N(C)C(C)c2ccco2)cc1OC +O=C(NCC1CCCc2ccccc21)c1ccnc(NC2CC2)c1 +CCC(C)(C)NC(=O)C(C)Sc1nnnn1C(C)C +COc1cccc(N2CCC(CNC(=O)Nc3cc(C)on3)C2)c1 +CCOc1ccc(CC(=O)N2CCC(C(N)=O)C2)cc1 +Cc1ccc(C(=O)NCC(=O)N(C)Cc2ccccc2)cc1 +CC(C)c1csc(NC(=O)c2ccc(Cl)c(N)c2)n1 +Cc1ccc(-c2nc(Cn3c(-c4ccccn4)noc3=O)cs2)o1 +Cn1c(=O)n(CC(O)COc2ccccc2)c2ccccc21 +CCN(CC)C(=O)CNc1cc(Cl)ccc1C(=O)N(C)C +COc1cc(NC(=O)c2n[nH]c3ccc(C)cc23)cc(OC)c1 +COc1ccc2[nH]cc(S(=O)(=O)c3ccc(C)c(C)c3)c(=O)c2c1 +COCc1nc(C(=O)N(C)CCc2cccc3ccccc23)cs1 +Cc1cc(S(=O)(=O)NCC(C)(O)C2CC2)c(Cl)cc1Cl +CNC(=O)COc1ccc(NC(=O)Cc2ccc[nH]2)cc1 +Clc1ccc2[nH]cc(CCNc3ncnc4oncc34)c2c1 +Cn1cc(CNc2ccccc2SC(F)F)cn1 +O=C(Nc1ccncc1)c1ccc(Cn2cnc3ccccc3c2=O)o1 +CC(C)c1ccc(C(NC(=O)Cn2cnnn2)C(C)C)cc1 +O=C(NCCOCC1CCCO1)c1c(Cl)cccc1Cl +COC(C)(C)c1noc(C(C)NC(=O)OC(C)(C)C)n1 +Cc1nc(CN(C)C(=O)CCOc2ccccc2)cs1 +CCc1c(C(=O)OC2CCCC2)[nH]c(C)c1C(C)=O +C=CCn1nnnc1SCC(=O)c1c(C)cc(C)cc1C +CCOC(=O)N1CCC(Nc2ncccc2F)CC1 +O=C(NCCC(=O)N1CCCCC1)c1cc2ccoc2s1 +COc1ccc2c(c1)C(=O)C(=O)N2Cc1ccc(F)cc1 +COC(C(=O)N(C)Cc1cccc2ncccc12)c1ccccc1 +CC(c1ccco1)N(C)C(=O)NCc1ccc(-n2ccnc2)c(F)c1 +Cn1cc(C(=O)NC2CCCC3OCCC23)c(C(C)(C)C)n1 +COC(=O)C(C)OC(=O)c1ccc(-n2cnnn2)cc1 +Cc1ccc(C)c(NC(=O)CCS(=O)(=O)N2CCNCC2)c1 +Nc1cc(C(O)CNc2ccccc2Cl)ccc1F +COC(=O)CNC(=O)c1ccc(F)cc1C#CCO +CS(=O)c1ccc(Oc2cccc(F)c2C#N)cc1 +Oc1ccc(Cl)c2c1CCNC2c1ccc(F)cn1 +Cc1ccc(Cl)cc1NC(=O)CCc1c(C)[nH]c2ncnn2c1=O +COc1cc(OC)c2[nH]c(C)cc(=O)c2c1Cl +NC(=O)c1cc(Cl)ccc1OCc1nc(-c2ccsc2)no1 +COc1ccc(N)cc1NC(=O)c1ccccc1OC +C=CCCC(=O)NCC#Cc1ccc(N(C)C)cc1 +CCCn1cc(-c2cc(-c3ccoc3)c(C#N)c(N)n2)c(C)n1 +CN(Cc1ccccc1)C(=O)c1cc2c(=O)n(C)c(=O)n(C)c2s1 +Cc1ccc(OCc2cccc(C(=O)NC3CCCC3)c2)cn1 +N#Cc1ccc(Oc2cccc(NCc3cn4cccnc4n3)c2)cc1 +O=C(NCCc1nc2ccccc2s1)NC1CCC(O)CC1 +CC(C)NC(=O)CSc1nnc(-c2ccco2)n1C1CCCCC1 +CN(Cc1ccoc1)C(=O)Nc1cccc(F)c1F +Cc1ccc(N(CCC#N)C(=O)c2scnc2C2CC2)cc1C +CS(=O)(=O)c1nccn1Cc1ccc(Cl)cc1 +COc1ccc(C(=O)N(C)C)cc1NCc1ccc(C#N)cc1F +COCCN(C)C(=O)c1sc(Cc2ccccc2)nc1C +COC(=O)Nc1ccc(OC(C)C(=O)Nc2ccc(C)cc2F)cc1 +Cc1nc2ccccc2n1CCNc1ncc(C(N)=O)cc1Cl +CC(C)Oc1ccc(C#N)cc1NC(=O)Cc1cccc(OCC#N)c1 +Nc1cc(N)nc(SCc2cccc(F)c2F)n1 +Cc1cc(CN(C)C(=O)CN(C)C(=O)c2ccccc2)no1 +CCCNC(=O)CN1C(=O)CSc2ccc(N)cc21 +Nc1ccc(Cl)c(NC(=O)c2cc(F)ccc2Br)c1 +CCCC(C)NC(=O)N1CCCCC1CNS(C)(=O)=O +COCCN1CCN(C(=O)c2nc3ccccc3s2)CC1=O +CC(C)(CNC(=O)c1cccnc1-n1cncn1)c1ccccc1F +Nc1cc(-c2ccc(Oc3ccccc3)cc2)no1 +Cc1nnc2n1CCN(C(=O)C(Oc1ccccc1C#N)C(C)C)C2 +CC(C)C(NC(=O)c1[nH]nc2c1COCC2)C(=O)Nc1ccccc1 +N#Cc1ccccc1CNc1ccc(Cl)c(O)c1 +O=C(Cc1cccs1)N1CCC2(CCCO2)C1 +Cc1cc(CN(C)C(=O)c2cccc(OCC(N)=O)c2)no1 +COCCN1CCN(C(=O)C2C3CC4CC(C3)CC2C4)CC1=O +COc1ccc(OCCN2CC(C#N)CC2=O)cc1 +C#CCOc1cccc(CN2CCc3nc(C)[nH]c(=O)c3CC2)c1 +Cc1cnc(C(=O)Nc2nccs2)c2cccc(N)c12 +C=CCOCc1cncc2c1CCN(C(=O)Cc1ccsc1)C2 +COCC(NC(=O)c1c[nH]nc1-c1ccc(Cl)cc1)C(N)=O +O=C(Cc1ccn[nH]1)NCC(O)c1cc(Cl)c2c(c1)OCCO2 +O=C(c1ccn(C(=O)c2ccccc2Cl)n1)N1CCCCC1 +CC(=O)NC(CC(=O)Nc1cccc2ccccc12)c1ccccc1 +CCc1[nH]nc(-c2ccc3c(c2)OCO3)c1NC(=O)C(C)C +Nc1nc(-c2ccccc2F)ncc1C(=O)Nc1ccncc1 +Cc1n[nH]c(C)c1NC(=O)c1cccc(COc2cccc(F)c2)c1 +COc1cc(C2NCCN(C)C2=O)cc(OC)c1OC +CCOc1cc(N)c(NC(=O)c2ccccc2)cc1OCC +Cc1nc(CNC(=O)Cc2ccccc2OC(C)C)no1 +COc1ccc(CC2C(=O)N(C)c3ccccc32)c(OC)c1OC +CCCNc1nc(-c2c(C)cc(C)n(C(C)C)c2=O)cs1 +CCC1CN(C)c2ccccc2CN1C(=O)c1nccnc1N +CN(Cc1cccc(Cl)c1Cl)C(=O)CNC(N)=O +Cc1nn(C)c(C)c1CCC(=O)NCCc1cnn(C)c1 +NC(=O)c1ccc(NCc2ccc(OC(F)F)cc2)cc1 +O=C1CSc2ccc(C(=O)N3CCCC(n4cccn4)C3)cc2N1 +O=C(OCCn1nc2ccccn2c1=O)c1ccc(Cl)cc1 +CC(Sc1nnnn1-c1ccc(O)cc1)C(N)=O +Cc1cccc(CNC(=O)NCc2ccnn2C)c1 +CCC(C)NC(=O)c1cccc(NS(C)(=O)=O)c1C +Cc1cc(-c2nn3c(-c4cnn(C)c4)nnc3s2)no1 +CCS(=O)(=O)Nc1ccc(C(=O)Nc2ccccc2C)cc1 +COc1cccc2c1OCC(NCc1cc(OC)c3c(c1)OCO3)C2 +O=C(Cc1ccsc1)N1CCCC(N2CCOCC2)C1 +C=C(C)Cn1c(N2CCOCC2)nc2c1c(=O)[nH]c(=O)n2C +O=C(NCc1noc(Cc2cccs2)n1)c1cnn2c1CCCC2 +O=C(c1ccc2cc[nH]c2c1)N1CC(c2nc(-c3cnccn3)no2)C1 +Cc1ccc(O)c(-n2nnc(-c3ccncc3)c2N)c1 +NC(=O)c1cccc(NC(=O)c2ccc(Br)cc2F)c1 +CC(=O)N1CCN(Cc2nc(-c3ccc4c(c3)COC4)cs2)CC1 +CC(=O)Nc1ccc(NC(=O)CC2C=CCC2)cc1 +COC(=O)C(CC(C)C)NS(=O)(=O)N1CC(C)CC(C)C1 +O=C1CCC(NC(=O)c2cccc(Oc3ccc(Cl)cc3)c2)CN1 +O=C(CNC(=O)c1cc(F)ccc1F)Nc1ccc(F)c(F)c1F +O=C(NCc1ccc(-n2cncn2)cc1)C1(c2ccc(F)cc2)CC1 +CC(C)C(O)C1(CNC(=O)NCc2cccnc2)CC1 +CCCCn1nnnc1NC(=O)N1C2CCCCC1CCC2 +Cc1ccn(C(C)CC(=O)Nc2ccc(C)c(Cl)c2)n1 +CCOC(=O)Cn1nc(C)c2c1N=C(O)CC2c1cccc(OC)c1 +COCc1cc(=O)n(CC(=O)Nc2ccccc2C)c(N)n1 +COCCCCNS(=O)(=O)c1ccc2c(c1)N(C(C)=O)CC2 +CC(=O)N1CCCC(c2cncc(Oc3ccccc3C)n2)C1 +Cc1ncc(CNC(=O)CCSc2nc3ccccc3s2)s1 +C=CCNC(=O)c1cc(-c2ccc(OC)cc2)no1 +Cc1ccc(C(=O)N2CCN(Cc3ccc(C#N)cc3)CC2)n1C +CC(=O)Nc1ccc(NCc2ccc(O)cc2)cc1 +Cc1ncc(CNC(=O)N(CC2CCCCC2)C2CC2)s1 +CCCCNC(=O)Cn1nc(C#N)cc1-c1ccncc1 +CC(C)C(=O)N1CCN(c2ccc(Cl)cc2Cl)C(=O)C1C +CCC(=O)Nc1cc(C(F)(F)F)ccc1N1CCN(CCO)CC1 +COc1ccccc1-n1nnc(C#N)c1CC(C)C +CCOC(=O)CNC(=O)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +Nc1cccc(CCNCc2ccc(S(N)(=O)=O)cc2)c1 +Cc1ccccc1C(C)NC(=O)CCc1c(C)noc1C +C=CCOc1ccccc1C(=O)Nc1ccn(C)n1 +CCCN(C)S(=O)(=O)c1ccc(Cl)c(C#N)c1 +CCOc1ccc(NC(=O)CCC(=O)Nc2nccs2)cc1 +COc1ccc(C(=O)NC(CO)c2ccccc2)cc1-c1ccccn1 +Nc1cc(F)cc2c(N3CCc4ccccc4C3)nccc12 +O=C(c1ccccc1Cl)N1CCCCC1CO +CC(O)CN(C)C(=O)CCNC(=O)c1ccco1 +COc1ccc(CN2CCOC(c3nc(C)cs3)C2)cc1O +CCC(C)C(NC(=O)CN1CCCCC1=O)C(N)=O +O=C(Cc1cccs1)NCc1ccc(-n2cnc3ccccc32)nc1 +CNC(=O)C1CCCN1C(=O)c1ccc(Br)cc1 +CCCn1nc(C)c(NC(=O)NC(C)c2cn3ncsc3n2)c1C +Cc1nc(C(=O)Nc2cccc(NC(=O)c3cccs3)c2)cs1 +COC(=O)Nc1ccc(CC(=O)NCc2cccs2)cc1 +CCOc1ccc(S(=O)(=O)NCC(=O)C(C)(C)C)cc1 +COc1ccc(C(C)Nc2cc(C)nc(C)n2)cc1F +CCc1nnc(SCC(=O)Nc2cc(Cl)ccc2C)o1 +O=C(NCCOc1ccccc1Cl)c1cnn2c1SCC2 +CCCNC(=O)CN(CC)S(=O)(=O)c1ccccc1 +CC(C)N(C(=O)c1ccccc1-c1cnc(N)cn1)C(C)C +Cc1cc(CCNC(=O)C2Oc3ccccc3OC2C)on1 +Cn1cc(N2CCC(NC(CO)c3ccccc3)C2=O)cn1 +COC(=O)Nc1cccc(NC(=O)N(C)Cc2ccco2)c1 +CC(C)CC(NC(=O)c1cc2cccnn2n1)C(=O)N1CCCC1 +CC(=O)N1CCN(C(=O)CNC(=O)c2cccs2)CC1 +Cc1cnn(CCC(=O)Nc2nnc(CC(C)C)s2)c1 +O=S(=O)(c1sccc1Br)N1CCCC1 +Cc1ccc2cc(C(=O)N3CCN(C(=O)N(C)C)CC3)[nH]c2c1 +CCc1nnc(NC(=O)Cn2nc(C)c3ccccc3c2=O)s1 +Nc1ccc(C(=O)N2CCc3ccccc32)cc1N +Cc1nnc(NC(=O)NCC2COc3ccccc3C2)s1 +CC(C)CNC(=O)CN1c2cccc3cccc(c23)S1(=O)=O +O=C(Cn1c(-c2ccccc2F)nc2ccccc21)N1CCOCC1 +CN(CC1CC1)C(=O)c1cc(-c2ccncc2)nc2ccccc12 +COC(=O)c1ccc(NC(=O)C(C)Sc2nc(C)n[nH]2)cc1 +N#Cc1nccnc1NCC1(CCO)CCOCC1 +CCC(=O)NCC1(Sc2ccccc2)CCOCC1 +Cc1nc(Cn2ccc(=O)c3ccccc32)sc1C +O=C(c1ccc(N2CCCC2)cc1)N1CCCC(O)(CO)CC1 +Nc1cccc(CCC(=O)NCCc2cccs2)c1 +CCN(CC)c1ncc(S(=O)(=O)c2ccccc2)c(N)n1 +COc1ccccc1CNC(=O)N1CCC(O)CC1 +CN1CCN(C(=O)c2cnc3c(cnn3C3CCCC3)c2)CC1 +CC1(C(=O)NCc2ccncc2)Oc2ccc(Cl)cc2NC1=O +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NC(C)c1ccccc1Cl +CCN(CC(C)C#N)C(=O)CSc1nc2ccc(C)cc2[nH]1 +N#CC(c1ccc(Cl)cc1)N1CCC(O)CC1 +Cn1cc(CC2CCN(C(=O)C3CC3c3ccc(Cl)cc3)C2)cn1 +COC(=O)C(OC)=C(c1ccccc1)c1ccccc1 +CCOc1ccc(S(=O)(=O)NCc2cccnc2)cc1NC(C)=O +CCCS(=O)(=O)N1CCC(O)(CNc2ccccc2)CC1 +Cc1ccc(C(=O)NCC(=O)Nc2ccc(C)c(Cl)c2)o1 +CC(C)C(C)NC(=O)CS(=O)(=O)c1ccccc1 +CCOc1ccc(NS(=O)(=O)c2ccccc2F)cc1 +CCC(C)NC(=O)CN1CCNc2cc(F)ccc21 +CCN(CC)C(=O)CNC(=O)NCc1ncccc1C +O=C(Nc1cnn(-c2ccccn2)c1)NC1CCCCC1CO +CC(C)n1nccc1NC(=O)Nc1ccsc1 +CCn1nc(C)c2c(C(=O)NCCn3cc(C)cn3)cc(C)nc21 +Cn1cc(NCc2cc(Br)c3c(c2)OCCCO3)cn1 +COc1ccccc1CCNCc1ccccc1OC +O=C(Nc1cccc(F)c1)c1ncc2c(=O)[nH]ccn12 +O=C(c1cnccn1)N1CCC(c2ccnc(-c3ccncc3)c2)C1 +NC(=O)c1cccc(NC(=O)CCc2ccccc2)c1 +CC(C)Oc1cccc(NS(=O)(=O)c2ccc3c(c2)OCCO3)c1 +COc1ccccc1N1CCN(C(=O)C2CNC(=O)N2)CC1(C)C +O=C(NCC1C2Cc3ccccc3C12)c1ccc(OCC(F)F)nc1 +Cc1noc(CCCC(=O)NC(C)c2ccc3c(c2)OCCO3)n1 +COc1ccccc1C(C)NC(=O)c1ccoc1C +COc1c(F)cc(NC(=O)c2ccc(F)nc2)cc1F +Cc1ccn(-c2ccc3c(c2)OCO3)c(=O)c1C#N +CC(=O)NCCCn1nccc1-c1ccc(F)c(Cl)c1 +COc1ccc(-c2cc(C)nc(N)n2)c(OC)c1OC +CN(C)S(=O)(=O)NCCNC(=O)Cc1cccc(F)c1 +CCOC(=O)CSc1nc2c(c(=O)n1C)SC(C)C2 +Cc1cccc(NC(=O)Cc2nc(Cc3ccccc3F)n[nH]2)c1C +COC(C(=O)Nc1ccc(C(=O)c2nccn2C)cc1)c1ccccc1 +COCC(=O)N1CCCCC1c1nc2ccccc2[nH]1 +CCC(CC)C(=O)N1CCC(NC(=O)NCC(C)(C)C(N)=O)CC1 +Cc1c[nH]nc1C1(C)CN(S(=O)(=O)c2cn(C)cn2)CCO1 +CC(C)C(CNC(=O)N(C)CCc1ccccn1)N1CCOCC1 +COC(=O)CC(NC(=O)C1CC=CCC1)c1ccc(F)cc1 +Cc1ccc(C(=O)NCc2ccc(-c3ccccc3)o2)c(=O)[nH]1 +CC(C)(C(N)=O)c1ccc(-c2cc(N)nc3[nH]ccc23)cc1 +Cc1ccc(NC(=O)COC(=O)c2c(O)cccc2O)c(C)c1 +Cc1nc(SCC(N)=O)n(C2CCCCC2)c1C +COc1cc2c(cc1OC)CCN(C(=O)COc1ccccc1)CC2 +O=C(Oc1ccc(-n2cnnn2)cc1)c1cnccn1 +Cc1nc2ccc(C(=O)NCCCOC(C)C)cc2nc1C +CN1CCN(C(=O)NCC(=O)OC(C)(C)C)c2ccccc21 +CC(C)(C)NC(=O)COc1ccc(S(=O)(=O)NC(C)(C)C)cc1 +CCN1C(=O)CCc2cc(NC(=O)Nc3ccccc3OC)ccc21 +COCC1(C(=O)NC2CN(CC(N)=O)CC2c2ccc(C)o2)CCC1 +COC(=O)c1sc(NC(=O)CSc2ccc(C)cc2)nc1C +CCOc1ccc(C(=O)Nc2nnc(-c3cc(C)nn3C)o2)cc1 +Cc1cc(NC(=O)C(C)Sc2ncccn2)no1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(C(C)C)[nH]n1 +CC1CN(C(=O)NCc2ccc(CS(N)(=O)=O)cc2)CCO1 +O=C(Nc1nccs1)c1nc(C2CC2)nn1-c1ccccc1 +Cc1ccc(NC(=O)c2cc(N)ccc2F)cc1Cl +Cc1n[nH]c(C)c1C1COCCN1C(=O)c1cc(C(C)C)[nH]n1 +CC(=O)N1CCN(C(=O)CCc2cc(Br)cs2)CC1 +O=C(Cc1c[nH]cn1)N1CCC2(CCCN(C3CCCC3)C2=O)C1 +Cc1ccc2c(C)c(C(=O)NCc3cccnc3)oc2c1C +COc1ccc(Cc2c(O)n[nH]c2N)cc1C(C)C +O=C(NCc1cccc2[nH]ccc12)c1ccc2occc2c1 +Cn1cc(C(=O)NC2CCOC3(CCN(c4ncccn4)C3)C2)cn1 +Cc1ccc(C(=O)NCc2ccccc2Cn2cccn2)c(=O)[nH]1 +CC(C)Oc1ccc(CCC(=O)NC2CC2)cc1N +COc1cc(NCC(c2cccnc2)N2CCOCC2)ncn1 +CCC(CC)NC(=O)Cn1cnc2ccccc2c1=O +CCc1nc(-c2ccc(C(=O)Nc3ccc(C#N)cc3)cc2)no1 +CN(C)C(=O)C1CCCN1C(=O)c1cccc(-c2ccoc2)c1 +O=C(NCC(O)c1ccco1)c1cnc(-c2ccccc2)s1 +c1ccc(-n2nnnc2CN2CC(n3cccn3)C2)cc1 +Cc1csc(NC(=O)c2sc3ccc(F)cc3c2C)n1 +Cc1cnc(C(=O)N2CCC(Oc3ccccn3)C3OCCC32)cn1 +COc1nn(C)cc1C(=O)N1CCN(S(=O)(=O)C2CC2)CC1 +COc1cc(C2(C(=O)NCC3CCC3)CC2)ccc1C +CCOc1ccccc1OCC(=O)Nc1nc(C(C)C)cs1 +CC(=O)Nc1ccc(NC(=O)c2ccccc2NC(C)=O)cc1 +CC(C)c1nc2n(n1)CC(NCc1cc(=O)n(C)c(=O)n1C)CC2 +CC(C)Oc1ccc(C(=O)N2CCNC(=O)C2(C)C)cc1 +COCC(O)CN(C)C(=O)c1ccc2c(c1)CCN2 +Cc1cc(C)n(CCCNC(=O)c2cc(-c3cccs3)cs2)n1 +CCc1cc2c(c(C(O)C(C)C)c1)NC(=O)C2CC +CC(=O)Nc1ccc(NC(=O)CN2CCc3cc(F)ccc3C2)cc1 +COC(=O)c1ccc2c(c1)CCN2C(=O)Cc1cn2ccsc2n1 +Cc1[nH]ccc1C(=O)NC(c1cccc(Cl)c1)c1ccccn1 +O=C1CN(C(=O)NCc2ccccc2Cn2cccn2)CCN1 +CCc1ccc(CNc2ccc3c(c2)NC(=O)CS3)o1 +Cn1cc(C(=O)CSc2ccccc2S(C)(=O)=O)cn1 +CCNC(=O)N1CCN(C(=O)c2ccc(F)c(F)c2)CC1 +CCn1c(=O)c(C(=O)Nc2ccccc2C#N)cc2cccnc21 +c1ccc(CNc2cc(-c3ncccn3)c3cc[nH]c3n2)nc1 +COc1ccc2nc(-n3cnc4ccc(N)cc4c3=O)sc2c1 +CCCn1nnnc1CNc1ccccc1OC(F)(F)F +COc1ccc(Nc2c(-c3nc(C)no3)cnc3nc(C)ccc23)cc1 +O=c1cc(C2CCC2)ncn1Cc1csc(-c2ccsc2)n1 +CC1(C)CCCN1C(=O)CCc1ccc(F)c(F)c1 +CCOC(=O)N1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 +Clc1ccc(OCc2cn3cccnc3n2)cc1 +Nc1ccc(OCc2ccc(F)cc2)c(Cl)c1 +O=C(NCc1csc(-c2ccccc2)n1)c1scnc1C1CC1 +CCOC(=O)CCC(C)NC(=O)NC1CCc2ccc(F)cc21 +CCCN(CC(=O)OC)C(=O)c1ccc(F)cc1N +COc1ccc(N)cc1NC(=O)C(C)Oc1ccccc1C +COc1ccc(C(C)NC(=O)Nc2ccc(F)c(C(N)=O)c2)cc1F +Cc1noc(COC(=O)CCC(=O)c2ccc(C)c(C)c2)n1 +O=C(Nc1cccc2ccccc12)C1CN(S(=O)(=O)C2CC2)C1 +CCC(C)Oc1cc(C(=O)N(C)Cc2nc(C)cs2)ccn1 +CC(=O)N1CCCc2cc(NC(=O)NCC(C)CC(C)O)ccc21 +Cn1ccc(C(=O)Nc2ccc3c4c(cccc24)CC3)n1 +Cc1sc(-c2ccno2)cc1S(=O)(=O)NC(C)(C)C +CN(C)C(=O)CN(c1ccccc1)S(=O)(=O)c1cccc(C#N)c1 +CN1C(=O)COc2ccc(NC(=O)NCc3ncc[nH]3)cc21 +Cc1nn(CC(C)C)c(C)c1CC(=O)Nc1ccc2c(c1)COC2 +N#CC1CN(Cc2ccc(OCC3CCCO3)cc2)CCO1 +CC(=O)Nc1ccc(C(=O)NC2CCc3cc(F)ccc32)cc1 +CCOC(=O)c1cnc(OC)nc1-c1ccccc1Br +CCn1c(CSc2nnnn2C)nc2c(F)cccc21 +Cn1c(C(N)c2ccncc2)nc2cc(O)ccc21 +CCCC(C)NC(=O)Nc1cnn(CC(N)=O)c1 +COc1cc(NC(=O)COC(=O)c2cccc(C)c2)cc(OC)c1 +CCc1ccc(OCC(=O)NCc2ccc3c(c2)OCO3)cc1 +Cc1ccc2nc(C)cc(C(=O)N3CCC(c4nncn4C)CC3)c2c1 +Cc1cccc(C(=O)OC(C)C(=O)Nc2ccccc2)c1O +COCCCn1cnnc1CNc1nc(C)nc2c1c(C)nn2C +Cc1ccc2nc(C(Cl)(Cl)Cl)oc2n1 +COc1cccc(C(=O)Nc2ccc(-n3ccnc3)cc2)c1OC +N#Cc1cccc(N2CCCC3(C2)CN(c2ccncn2)CCO3)c1 +CC(Oc1ccccc1Cl)C(=O)Nc1ccon1 +CCCc1nc(CN(C)S(=O)(=O)c2ccc(OC)cc2)cs1 +Nc1nccnc1OCc1ccc(Cl)cc1Cl +CCN1CC(C(=O)N2CCc3ccccc3C2)CC1=O +CCOc1ccc(-c2cc(-c3ccc(C)o3)nc(N)n2)cc1 +CNc1cc(S(=O)(=O)N2CCCC(C)C2)ccn1 +Cc1nc(C2CN(CC3CCCCC3)CCO2)no1 +Cc1[nH]c(=O)c(C(=O)N(CCO)Cc2ccccc2F)c(C)c1C +CCc1c(C(=O)Nc2nc[nH]n2)cnn1-c1ccc(F)cc1 +CC(C)NC(C#N)CCSc1n[nH]c(=O)n1C +CC(=O)c1ccc(NC(=O)c2ccc3c(c2)CCN3C(C)=O)cc1C +CCc1cc(-c2cccc(OC)c2OC)nc(N2CCOCC2)n1 +Cc1cc(C(C)NC(=O)C(C)NC(=O)c2ccoc2)c(C)s1 +Cn1ncc2c(N3CCCc4ccccc43)ncnc21 +O=C(NCC1(O)CCCCC1)Nc1cccc(F)c1 +Cc1ccc(CNC(=O)c2sc(C)nc2C)cc1 +O=S(=O)(N1CCOCC1)C(F)(F)c1nc2ccccc2s1 +Cc1ccc(C(CNC(=O)C2CC=CCC2)OCCO)cc1 +CC(c1ccco1)N(C)C(=O)CCNC(=O)c1n[nH]c2ccccc12 +Cc1cnccc1Cn1c(C)cc(C(F)(F)F)cc1=O +CSc1ccccc1NC(=O)c1cnc2cc(C)ccn2c1=O +Cc1ccc(-c2noc(-c3ccccc3C(=O)N(C)C)n2)cc1 +CCN(Cc1cccc(F)c1)C(=O)c1ccc(=O)[nH]c1 +O=c1c2ccccc2sc2nc(C(F)(F)F)nn12 +CNC(=O)Cc1ccc(NS(=O)(=O)c2ccc(C)cc2C)cc1 +CN1CC(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)CC1=O +Cn1cc(C(=O)N(Cc2ccccc2)C2CC2)c(-c2cccs2)n1 +COc1ccc(Cl)cc1C(C)NC1CCN(c2cnn(C)c2)C1=O +O=C1CCCNc2c(Br)cc(Br)cc21 +CC(C)n1cc(C(=O)NCCc2nc(-c3ccccn3)no2)cn1 +Cc1nccn1-c1ccc(C(C)Nc2ccc(C(N)=O)nn2)cc1 +O=c1c(F)cn(C2CCCO2)c(=O)n1Cc1ccccc1Cl +COCC(=O)N1CCCC1c1cc(=O)cc(C)[nH]1 +CCOc1ccc(C(=O)C2CCCN2S(=O)(=O)CC)cc1 +CC(C)NC(=O)c1ccccc1NC(=O)Cc1ccccc1 +COC(=O)c1sc2nc(C)nc(N3CC(C)OC(C)C3)c2c1C +N#CC(NC(=O)CCCOc1cccc(F)c1)c1ccccc1F +COC(=O)N1CCC(NC(=O)COc2ccc(C)cc2C)CC1 +CCn1cnnc1CNC(=O)NCc1ccnn1C +CS(=O)(=O)NCCc1ccc(C(=O)Nc2ccccc2)s1 +CC(C)(C)OC(=O)N1CCC(CNc2nc3ccccc3nc2N)C1 +CC(NC(=O)CCNC(=O)Nc1ccccc1)c1ccccc1Cl +CCOC(=O)CNC(=O)N1CCCC1c1c(C)noc1CC +COCC(=O)NC(C)c1ccc(-c2cncnc2)cc1 +CC(=O)N1CCN(c2ncc(-c3ccccc3)cc2C#N)CC1 +CC(C)(C)NC(=O)c1cc(-n2cccn2)ccc1F +CC(Oc1ccc(-c2nc3ccccc3s2)cc1)C(N)=O +Cc1ccc(C)c(N2CC(C(=O)Nc3cc(C)on3)CC2=O)c1 +CC(Sc1nncs1)C(=O)N1CCCC1c1cccs1 +Cc1cc(C#N)c(NC2CC2)nc1-c1ccc2c(c1)OCCO2 +COc1ccc(OC)c(NCC(=O)N(C)Cc2ccccc2)c1 +CCN(CCO)C(=O)c1c(C)cc(C)n(C)c1=O +CC(c1ccc(F)cc1)N(C)C(=O)NCc1nnc2ccccn12 +Cc1ccc(NCc2nc(C3CC3)no2)cc1-n1cnnn1 +COCC(C)NC(=O)CCNC(=O)c1ccccc1 +Cc1noc2nc(C(C)C)cc(C(=O)N(C)Cc3cnn(C)c3)c12 +N#CCc1nc(-c2cc3cc(Br)ccc3oc2=O)cs1 +CC(C)(C)NC(=O)NCC#Cc1ccc(N2CCOC2=O)cc1 +COC(=O)c1cc(Cn2cc(-n3cccc3)cn2)c(C)s1 +CCCN(CCC)C(=O)c1ccc(C(=O)N(C)C)cc1 +Cc1ccc(OCC(=O)Nc2ccnn2CC(C)C)c(C)c1 +COC(=O)c1ccc2c(c1)CCN2C(=O)C(OC)c1ccccc1 +O=C(NCc1cccc(CO)c1)c1cc2cccc(F)c2o1 +CN(Cc1ccc(O)cc1)C(=O)NCc1nnc2n1CCCCC2 +CSc1nc(N)nc(SCC(=O)OCc2ccccc2)c1C#N +Cc1ccc(CCC(=O)OCc2ccccc2C(N)=O)c(C)c1 +Cc1n[nH]c(C)c1CCC(=O)N(Cc1ccco1)Cc1cccs1 +CCN1CC(C(=O)Nc2cc(C)ns2)CCC1=O +COc1cc(CN(C)C(=O)NC2CCC(O)CC2)ccc1SC +CCOc1ccc(NC(=O)CCc2ccco2)cc1Cl +Cc1ncc2c(n1)CCN(C(=O)c1ccc(F)cc1)C2 +COC(=O)C(O)c1cc(Cl)cc(Cl)c1OC +COc1cc(C2(C(=O)NCCNC(C)=O)CC2)ccc1C +COCC(C)NC(=O)CCSc1ccc(F)cc1 +COC(=O)c1ccc(C(=O)N(C)Cc2csc3ccccc23)cc1 +Clc1ccc2nc(CN3CCN(c4ncccn4)CC3)cn2c1 +COc1cccc(CCC(=O)N2CCOCC(O)C2)c1 +CCN1CCN(C(=O)c2c[nH]nc2-c2ccccc2Cl)CC1 +Cc1cc(OCC(=O)NCC(C)(O)c2ccsc2)ccc1C(C)C +CC(C)Oc1cccc(F)c1-c1nc(N(C)C)n(C)n1 +Cc1ccccc1-n1cnnc1SCC(F)F +O=C(c1ccc(=O)n(-c2ccccc2)n1)N1CCCC2CCCCC21 +Cc1cc2nc(C)c(=O)n(CCC(=O)NC(C)C)c2cc1C +CC(C)(C)CN(CCC#N)C(=O)c1ccc(-c2ccco2)[nH]c1=O +CC(=O)NC1CCCN(C(=O)Nc2ccc(OC(C)C)cc2F)C1 +O=C(Cc1cccs1)Nc1cccn2nc(C3CCC3)nc12 +COc1ccccc1C1(CNC(=O)CC(C)(C)C)CCOCC1 +O=c1[nH]cc(S(=O)(=O)N2CCC(CO)CC2)c(=O)[nH]1 +Cc1nc(-c2nc(C)n(CC(F)(F)F)n2)cs1 +CC(=O)Nc1ccc(SC(C)C(=O)NCC(F)(F)F)cc1 +O=C(NC1C=CC(CO)C1)NC1CCCN(c2ccccc2F)C1=O +CCN(CC)S(=O)(=O)CC(=O)Nc1ccc(F)c(C)c1 +O=C(CCO)N1CCN(C(=O)c2cccc(F)c2)CC1 +COc1ccc(C(=O)Nc2cc(C(C)=O)ccc2C)cc1 +Cc1oc(-c2ccco2)nc1CN1CCc2cnc(C(C)C)nc2C1 +COc1cccc2sc(C(=O)NC3CCCCC3)nc12 +O=C(NCc1ccc(Cn2cncn2)cc1)Nc1cccnc1 +Cc1cc(C)nc(NC(=O)NCCn2cccc2)c1 +COc1ccc(NC(=O)Cc2nc3ccccc3c(=O)[nH]2)cc1 +Cc1ccc(C(O)CNC(=O)c2ccc[nH]c2=O)cc1 +Cn1c(=O)[nH]c(=O)c2c1ncn2Cc1c(F)cccc1Cl +COc1cc(C(=O)NCC(C)C)ccc1OC(F)F +Cc1ccc(C(=O)N2CCCC3(CCC(=O)N(CCO)C3)C2)cc1O +CC(C)(C)C(OC(=O)c1ncn(-c2ccccc2)n1)C(F)(F)F +O=C(Cc1ccc(F)cc1)Nc1cccn(Cc2ccccc2)c1=O +CCN(Cc1cccc(F)c1)C(=O)CCC(=O)N1CCOCC1 +[H]N=c1sc(C(=O)c2cccs2)nn1-c1ccccc1 +CCOc1ccc(NC(=O)Cn2nnc(C(=O)OC)c2N)cc1 +Cc1csc(NC(=O)NCC(C2CCOC2)N2CCOCC2)n1 +CCNC(=O)CN(CC)C(=O)CCc1cccc(F)c1 +CCCCC(=O)Nc1ccc(C2(C(=O)NC)CC2)cc1 +CC(c1ccccc1F)N(C)CCc1ccccn1 +CCN(CC)C(=O)NCCc1nnc2n1CCCCC2 +O=C(NCC(F)(F)F)c1cccc(Cl)c1Cl +O=S(=O)(CS(=O)(=O)Oc1ccccc1)Oc1ccccc1 +Cn1c(C2CC2)nnc1S(=O)(=O)CC(=O)NCCc1ccccc1 +Clc1cc(Cl)c(OCc2nnnn2C2CC2)cc1Cl +O=C(CN1CCN(c2ccc(F)cc2)C1=O)NC1CCCC1 +CCCCCCNC(=O)C1CCCCN1C(=O)c1ccccc1 +CCN(C(=O)c1cc(C)n2ccnc2n1)c1cccc(C)c1 +CC(=O)N1CCCN(C(=O)CCCNC(=O)c2ccsc2)CC1 +O=C(NC1c2ccccc2CC1O)c1cccc(Cl)c1F +CCCS(=O)(=O)N1CCC2(CCCN(c3ncc(F)cn3)C2)C1 +CC(C)c1ncc(Cl)c(C(=O)Nc2cccnc2-n2cccn2)n1 +Cc1cccc(S(=O)(=O)NC2(C#N)CCCCC2)c1 +O=C(NCc1ccc(-n2cncn2)nc1)c1n[nH]c2ccccc12 +COc1ccc2nc(SCCC(=O)Nc3ccccc3)[nH]c2c1 +Cc1noc(C)c1S(=O)(=O)N1CCN(C(C)c2ccccc2)CC1 +O=C(Nc1ccc2nonc2c1)c1ccccc1O +O=C(CSc1ncn[nH]1)c1ccc2c(c1)OCO2 +C#CCCOC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +CC(=O)c1cccc(NC(=O)C(C)Nc2cccc3c2OCCO3)c1 +O=S(=O)(NC1CC1)c1ccc(NC2CCCCC2)nc1 +c1ccc2[nH]c(CCc3nc(-c4ccncc4)no3)nc2c1 +CCN(C(=O)c1cccnc1)c1cc(C)cc(C)c1 +Cc1cccc(NC(=O)c2ccc(N3CCOCC3)nc2)c1 +O=C(Nc1cccc(F)c1)c1ccc2ccnn2c1 +C#CCNC(=O)Cn1nc(-c2ccccc2)ccc1=O +COc1ccc(CN(C)c2c(C#N)nnc3ccc(C)cc23)cc1OC +COC(=O)CCNC(=O)CN1CCN(c2ccccc2)CC1 +O=C(CCNC(=O)c1ccnc2c1OCO2)NCc1cccs1 +O=C(Nc1ccc(F)cc1)c1cccn2cncc12 +O=C(Nc1cccc(N2CCNC2=O)c1)N1CCCCCC1 +c1coc(CNc2ncnc3sc4c(c23)CCCC4)c1 +CNC(=O)C(CC(C)C)NC(=O)CNC(=O)c1ccc(C)c(C)c1 +CCc1nc(CN(C)Cc2nc3c(cnn3C)c(=O)[nH]2)cs1 +C=CCNC(=O)NCCNC(=O)c1cccc(Br)c1 +CNC(=O)c1ccccc1OS(=O)(=O)c1ccc2c(c1)CCC2 +CC(C)=Cc1c(-c2ccccc2)ncn1C(C)C(N)=O +Cc1nn(C)c2ncc(C(=O)NCc3ccc4c(c3)CCC4)cc12 +Cc1nc(CC(=O)NC(C)Cc2c(Cl)cccc2Cl)cs1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)C(C)C)c1 +O=C1NC2(CCN(C(=O)c3cccs3)CC2)CC1c1ccncc1 +O=C(OCc1nnnn1-c1ccccc1)c1ccc(C(F)(F)F)cc1 +COc1cc(NC(=O)CC(C)(C)C)c(C(N)=O)cc1OC +O=C(c1ccccc1-c1ccccc1)N1CC2C3CCC(O3)C2C1 +CC(C)CC(NC(=O)C1CCC(C)CC1)C(=O)NCc1cccnc1 +Clc1cccc(-c2nnc(-c3ccncc3)o2)c1 +O=C(Nc1ccc(-n2cnnn2)cc1)C1CCCCC1 +Cc1ccc2c(CC(=O)Nc3ccnc4ccnn34)coc2c1C +COc1ccc(NC(=O)c2ccc(C)cc2O)cc1OC +Cc1noc(C(C)NC(=O)Nc2ccc3nc(C)sc3c2)n1 +CC(C)Nc1nnc(Sc2ncnc3ccsc23)s1 +CCOc1ncccc1C(=O)NC1CC(=O)N(CC(F)(F)F)C1 +CC(NC(=O)CCC1CCCC1)c1ccc(S(C)(=O)=O)cc1 +Cc1csc2nc(CN3CCCc4cc(F)ccc43)cc(=O)n12 +CC(Cn1cccn1)NC(=O)C1CCCCN1S(C)(=O)=O +O=C(CC(c1ccccc1)c1ccco1)N1CC(c2cccnc2)C1 +Cc1ccccc1CC(=O)OCC(=O)NCc1ccc(F)cc1 +CCNC(=O)CNC(=O)c1cc(C)cc(Br)c1O +CC(=O)NC(C)(C)c1noc(-c2cc3ccccc3c(=O)[nH]2)n1 +Cc1ccc2c(C)c(-c3nc(C4CCOC4)no3)oc2c1 +COC(=O)C1CCN(C(=O)COC2CCCCC2C)c2ccccc21 +O=c1[nH]c2ccc(F)cc2n1-c1ccc(C(F)(F)F)cc1 +CC(=O)c1cccc(NC(=O)Nc2ccc(C#N)cc2)c1 +O=C1CN(C(=O)c2cc3ccccc3cc2OC(F)F)CCN1 +O=c1c2cc3c(=O)n(Cc4ccccc4)ccc3nc2ccn1CCO +CCC(C(=O)NC1CC1)n1nc(C)n2c(cc3occc32)c1=O +O=C(NCc1ccc(Cl)cc1)Nn1cnc2ccccc21 +CC(NC(=O)CCn1c(=O)sc2ccccc21)c1ccccc1 +Nc1ccc(F)c(S(=O)(=O)NCC2CCCCO2)c1 +CCc1nnc(NC(=O)N(C)CCOc2ccc(F)cc2)s1 +O=c1cc(-c2ccccc2)[nH]c(=O)n1Cc1ccccc1 +O=C(Nc1ccc(F)cc1)C1CCN(C(=O)c2ccncc2)CC1 +O=C(Cn1cccn1)N1CCC(Oc2ccccn2)CC1 +Cc1occc1C(=O)Nc1ccc(NC(=O)C2CC2)cc1 +Cc1nc(C(=O)N2CCC(CC(N)=O)CC2)nn1-c1ccc(F)cc1 +CN(C)C(=O)COC1COC2(CCN(Cc3nccs3)CC2)C1 +C#CCNC(=O)c1cc(S(=O)(=O)N(C)C(C)C)ccc1F +CC(C)COCC(NC(=O)c1ccc2c(c1)OCO2)c1ccco1 +c1cnc(-c2cnc(N3CCCCCC3)nc2-c2ccoc2)cn1 +CCN(C(=O)CCc1cccs1)C1CCCC1 +CC(C)CC(=O)N(C)CCc1noc(-c2cc3ccccc3[nH]2)n1 +CC(C)NC(=O)CCn1cnc2onc(-c3cccc(F)c3)c2c1=O +CC(C)(C)CC(=O)NCC1CCN(C(=O)Oc2ccccc2)CC1 +O=C(NCCNC(=O)c1ccco1)c1cc2n(n1)CCCO2 +COCC(C)NC(=O)COc1cc(C)cc(C)c1 +Cc1cc(S(=O)(=O)Nc2ccccc2-c2nncn2C)c(C)s1 +COCC(=O)N1CCC(Oc2cc(N3CCCC3)ncn2)C1 +CC(C)NC(=O)c1ccc(F)c(S(=O)(=O)NC(C)(C)C)c1 +C#CCN(CC(=O)NC(C)C(C)C)Cc1ccc(F)cc1 +Clc1cnc(SCc2nnnn2C2CC2)c(Cl)c1 +O=C(NCCC1=CCOCC1)Nc1ccc2c(c1)COC2 +COC(=O)C1(N(C)C(=O)CNC(=O)c2ccccc2)CCCCC1 +CC(O)CN1CCN(C(=O)c2cn(CC#N)c3ccccc23)CC1 +CCc1nnc(CN(Cc2ccccc2)Cc2ccccc2)o1 +Cc1ccc(-n2c(SCCCO)nc3ccccc3c2=O)cc1 +Cc1nc(C)c(C(=O)Nc2ccc(Oc3cccnc3)nc2)o1 +Cc1cccc(NC(=O)Cn2c(=O)c(N(C)C)c(N)n(C)c2=O)c1C +COc1ccc(C)cc1NC(=O)CSc1nncn1C1CC1 +O=C(Nc1ccnc2[nH]ncc12)c1ccccc1OC(F)(F)F +O=C(NCCN1CCOCC1)N(Cc1ccccc1)CC(F)F +O=C(NC1CC1)c1ccc2c(c1)S(=O)(=O)N(C1CC1)C2=O +Cc1nn(C(C)CC(=O)NCc2ccco2)c(C)c1Br +CCOC(=O)N1CCN(CC(O)COc2ccccc2C)CC1 +CC(=O)N1CCCC(C(=O)NCc2c(C)cc(C)[nH]c2=O)C1 +O=c1cc(C2CCC2)ncn1Cc1ccccc1OC(F)F +CC(C)CCOc1ccc(C(=O)N2CCN(CCC#N)CC2)cc1 +CCn1c(C)cc2cc(NC(=O)NCCN3CCNC3=O)ccc21 +O=C1CCCCC1Sc1nnc(SC2CCCCC2=O)s1 +CC(=O)NCC(=O)c1ccc(Br)cc1 +COc1ccc(C2(Cc3ccc4c(c3)OCO4)NC(N)=NC2=O)cc1 +Cc1cccc(NC(=O)CN(C)C(=O)C2CCCO2)c1C +O=C(NCc1cccc(N2CCCC2=O)c1)OCC(F)(F)F +CC(C)NS(=O)(=O)c1ccc(NC(=O)c2ccccn2)cc1 +CC(C)CC(=O)Nc1ccc(C2OCC(=O)NC2CO)cc1 +CCCc1cc(N2CCCCC2Cn2cc(C)cn2)n2ncnc2n1 +CCN(CC(=O)NC(C)(C)C)C(=O)NCc1ccc(C)s1 +CNC(=O)c1ccc(CNc2nc(-c3cccc(OC)c3)no2)cc1 +COc1cc(Cl)c(O)cc1NC(=O)Cn1nnc2ccccc21 +COC1CCCC(OC(=O)c2ccc(NC(=O)C3CC3)cc2)C1 +O=C(NCCCn1ccc2ccccc21)c1cnc2ccccn2c1=O +COC(=O)c1c(NCc2ccc(C)o2)c2cccc(Cl)c2[nH]c1=O +O=C(Cn1cncn1)NC1c2ccccc2Oc2ccccc21 +Cc1noc(COCC(=O)NCC(C)(C)c2ccccc2Cl)n1 +CCCCNC(=O)c1cccc(S(=O)(=O)N2CCCCC2C)c1 +COc1ccccc1CNC(=O)c1cc(-c2cccnc2)[nH]n1 +Cc1cnc(C(=O)N2CC=C(c3ccccc3Cl)CC2)cn1 +CC(C)CCNS(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +CCNC(=O)N1CCC(C(=O)NCc2ccc(C)c(F)c2)CC1 +CC1CCN(C(=O)C(C)Nc2ccc(N3CCCC3=O)cc2)CC1 +COCCOc1c(Cl)cccc1NC1CCN(C(C)=O)CC1 +Cc1cc2c(SCC(=O)NC3CCCCC3)ncnc2s1 +CC(Sc1nnc(-c2ccncc2)o1)C(=O)NCC(F)(F)F +CN(C(=O)c1ccc(F)c(F)c1F)C(C#N)c1ccco1 +CN(C)S(=O)(=O)c1ccc(OC(=O)c2cccc3cn[nH]c23)cc1 +Cc1ccc(-n2ncc3c(=O)[nH]c(C)nc32)c(C)c1 +CCn1cc(C(=O)Nc2cnn(CC)c2C(N)=O)cn1 +NC(C(=O)NCCc1ccccc1)c1ccccc1 +N#CCOC(=O)CCn1nc(-c2cccs2)oc1=O +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)N(C)Cc1cn(C)nc1C)O2 +O=C(c1ccc2c(c1)Cc1ccccc1-2)N1CCOCC1 +Cc1cc(C)c2nc(NC(=O)c3ccn(C)c(=O)c3)sc2c1 +COCCOCC1CCN(S(=O)(=O)c2cccc(Cl)c2)CC1 +CNc1snc(C)c1C(=O)NCCOc1ccc(F)cc1 +CN(CC(=O)Nc1nccs1)Cc1nc2ccccc2s1 +CC(C)C(C(=O)NC(c1ccccc1)c1ccccc1)N1CCC1=O +O=C(Cc1cnn(-c2ccccc2)c1)OCC(=O)C1=NC=CC1 +CC(=O)c1c(C)[nH]c(-c2csc(-c3ccco3)n2)c1C +CCn1c(CN2CCOCC2)nc2cc(NC(C)=O)ccc21 +CN(Cc1nccn1CC(F)(F)F)C(=O)CC(C)(C)C +CCCn1nc(C(=O)N2CCCC(n3nc(C)nc3C)C2)ccc1=O +Cc1noc(C(C)C)c1C(=O)N1CCC(n2cccn2)CC1 +CNC(=O)NCC(=O)N(C)C(C)c1ccccc1Br +Cn1ccnc1C(=O)NCCc1nc2cc(F)ccc2s1 +O=S(=O)(c1ccc(SC2CCCC2)nc1)N1CCOCC1 +CCc1nc(CC(=O)NCCc2nnc3n2CCCCC3)cs1 +COc1ccccc1CNS(=O)(=O)c1cccc(C(F)(F)F)c1 +Cc1ccccc1S(=O)(=O)Nc1cccc2[nH]ccc12 +C=CCN(Cc1cccs1)C(=O)c1cc(OC)ccc1O +Cc1cc(Sc2ncccn2)ccc1NC(=O)Nc1cnn(C)c1 +Cc1cc(F)ccc1NC(=O)N1CCN(C(=O)c2ccoc2)CC1 +OC1CCN(c2ccnc(NCc3ccc4c(c3)OCO4)n2)C1 +CN(C)C(=O)CCc1ccc(NC(=O)C2CCC2)cc1 +Cc1[nH]c2ccccc2c1C(=O)COc1cc(Cl)ccc1C(N)=O +CN(CCN(C)c1ccccc1)Cc1cnc(C2CC2)s1 +COC(=O)C(C)N1CCN(c2ccccc2OC)CC1 +Cc1cccc(OCC(=O)Nc2ccc(CC(=O)NC3CC3)cc2)c1 +COc1ccc(-n2ccc(CNC(=O)NCCC(C)C)n2)cc1 +N#Cc1c(-c2ccc(Cl)cc2Cl)cc[nH]c1=O +c1ccc(Oc2cccc(NCc3nnc(C4CCC4)o3)c2)nc1 +Cc1nc(C(=O)N2CC(c3n[nH]c4ncccc34)C2)co1 +CN(C)C(=O)Cc1ccc(NCc2ccc(Cl)cc2)cc1 +O=C(Cc1ccccc1F)N1CCN(C(=O)C2CC3CCC2O3)CC1 +CC(C)COC(=O)Nc1cccc(NC(=O)Nc2cccnc2)c1 +CC(C(=O)NCC(F)(F)F)N1CCOC(C)(C)C1 +CN(Cc1ccc(S(C)=O)cc1)C(=O)Cc1ccc[nH]1 +Cc1cccc(NC(=O)NC2CCN(c3ccccc3)C2=O)c1 +CCOc1ccc(C(=O)Nc2c(C)nn(C)c2C(=O)OC)cc1 +Cc1nc2ccc(C(=O)Nc3cc[nH]n3)cc2nc1C +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)N(C)C2CCC(C)CC2)c1 +COC(=O)c1nn(C)c2nc(N)nc(N)c2c1=O +COC(=O)C1c2ccsc2CCN1C(=O)c1sc(C)nc1C +CCCCSc1nc(=O)c2cnn(CCO)c2[nH]1 +Cc1csc(N(C)C(=O)CCc2ccc3c(c2)OCO3)n1 +CCn1c(SCc2ccccc2C)nc2c(cnn2CCO)c1=O +Cc1cccc(N(CCC#N)C(=O)COc2ccc(C#N)cc2)c1C +CCc1csc(N(C)C(C)c2cccc(N)c2)n1 +CC(C)CCNC(=O)CCN1C(=O)c2ccccc2S1(=O)=O +O=C(CNC(=O)c1ccc(Cl)cc1)OCC(=O)c1ccc(F)cc1 +COc1cc(-c2noc(C=Cc3cnc(C)s3)n2)ccn1 +CC1CN(S(=O)(=O)NCCCC2CCCCC2)CC(C)O1 +NC(=O)C(NCc1csc(-c2ccc(F)cc2)n1)c1ccccc1 +O=C(NCCC1CC1)NC(CC(F)(F)F)c1ccc(F)cc1 +Cc1nonc1NC(=O)COc1ccc2oc3c(c2c1)CCCC3 +C=CCn1c(SCC(=O)NC2CCOCC2)nc2ccccc21 +O=C(Cn1ccnn1)Nc1ccnn1Cc1cnn(-c2ccccc2)c1 +CCNC(=O)N1CCc2ccc(NC(=O)c3cnc[nH]3)cc21 +CCN(C(=O)c1cc(Br)cnc1NC)C1CC1 +COc1ccccc1NC(=O)N1CCCC1CC(O)c1ccco1 +N#CC(Cc1ccc(O)cc1)C(=O)N1CCCc2ccccc21 +O=C(CCc1cccc(F)c1F)Nc1nnc(-c2ccccn2)s1 +CC1CCC(C(N)=O)CN1C(=O)c1cn(Cc2ccccc2)nn1 +CC(C)NC(=O)N1CC2CN(Cc3ccncc3)C(=O)C2C1 +Cc1noc(C)c1CCCNc1ccc2cc[nH]c2n1 +CCC1COCCN1S(=O)(=O)c1ccccc1C#N +CC(C)N(Cc1cccc(N)c1)C(=O)c1cccs1 +CN(CC1CCCO1)C(=O)C1CCCN1C(=O)OCC(F)(F)F +COc1ncccc1C(=O)NC(C)Cc1ccco1 +Cc1cccc(-c2n[nH]cc2C(=O)N2CCn3cncc3C2)c1 +C=CCn1c(=O)c(=O)n(Cc2ccc(C(=O)NC)cc2)c2ccccc21 +C=CCCC(=O)Nc1ccc(NC(=O)OC)c(F)c1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2ccc(C)cn2)cc1 +Cc1cccc(NC(=O)CCN2C(=O)CCc3ccccc32)n1 +Cc1cc(C(=O)N2CC(C(=O)NCCCn3ncccc3=O)C2)no1 +CNC(=O)CC1CCN(C(=O)c2cc3cc(C)ccc3n2C)CC1 +NC(=O)c1ccc(OCC(=O)N2CCNCC2)cc1 +CC(C)(C)C(O)(CCc1ccccc1)Cn1cncn1 +COc1cccc2cc(C(=O)Nc3ccc(C)cc3)c(=O)oc12 +O=C(C1COc2ccc(F)cc2C1)N1CCCC1c1ccco1 +CCC1(CC)CNc2cc(S(=O)(=O)CC(C)C)ccc2O1 +NC(=O)c1cccc(Cc2nc3ccc(F)cc3c(=O)[nH]2)c1 +N#Cc1cccc(C(=O)N2CCCC2C(O)c2nccs2)c1 +COCC(=O)Nc1cccc(NC(=O)NCc2ccc(Cl)cc2)c1 +CCC(C)N(C)C(=O)Nc1cccc(NC(=O)OC)c1 +Cc1cc(=O)n2nc(NCC3CCCCC3)sc2n1 +COc1cc(N2CCC(CO)CC2)nc(SC)n1 +Cc1occc1COC(=O)c1ccc(-n2cccn2)c(F)c1 +NS(=O)(=O)c1c(OC2CC2)cncc1C(F)(F)F +CCOCCNC(=O)N1CCCC(c2nnc3ccccn23)C1 +COCC(C)NC(=O)c1cc(OC)ccc1OC +CCC(CO)NC(=O)Nc1ccn(-c2cccc(C(F)(F)F)c2)n1 +O=C(Nc1ccccc1F)c1ccc(-n2cnc3cccnc32)cc1 +COC(=O)c1cccc(NC(=O)CNC(=O)C2CCCC2)c1 +Cc1nc(N(C)Cc2c[nH]nc2-c2ccccc2)c2cnn(C)c2n1 +O=C(NCCc1ccccn1)c1nc(N2CCCC2)ncc1Cl +CC(c1ccsc1)N1CCN(C(=O)Nc2ccnn2C(C)C)CC1 +O=C(COCC1CC1)Nc1ccc(-n2cccn2)cc1C(F)(F)F +CC1CN(C(C)C(N)=O)c2ccc(Br)cc2N1 +Cc1c(C(=O)Nc2cc(F)ccc2Cl)cnn1-c1ccncc1 +CCCCC1CCC(NC(=O)NCc2cccc(C(N)=O)c2)CC1 +Cn1cc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c2ccccc21 +Cc1nc(CCNC(=O)Nc2ccc(F)cc2C#N)cs1 +Cc1nnc(NCc2ccc(Br)cc2)o1 +O=S(=O)(CC1CCCO1)N1CCCc2cc(F)c(F)cc21 +O=C(CCc1ccccc1)Nc1nnc(CSc2ccccc2)o1 +CC(CO)CNC(=O)NCCNC(=O)c1ccc(F)cc1 +CC1=C(C(N)=O)C(c2ccccc2Cl)N(C)C(=O)N1C +Cn1cnc2cc(OC(=O)CNC(=O)OC(C)(C)C)ccc21 +Cc1cnn(C)c1C(=O)N1CCN(c2nc3ccccc3s2)CC1 +CC(C)(Br)c1nnc(-c2nonc2N)o1 +CCn1cc(CNS(=O)(=O)c2cc(Cl)ccc2Cl)c(C)n1 +O=c1cc(CNCC2(O)CCCCC2)[nH]c2ccc(F)cc12 +CCOCCNC(=O)N(CC)Cc1ccccc1C#N +COc1ccnc(N2CCN(C(=O)Cn3cc(C)cn3)CC2)n1 +CCN(C(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1)c1ccc(F)cc1 +CN(CC1CC1)C(=O)c1c[nH]c2ccccc2c1=O +CCOC(=O)NCCC(=O)N1CCCc2ccccc21 +CCN(CC)S(=O)(=O)c1cc(NC(=O)C2CC2C)ccc1C +CCCNc1nnc(-c2cccn(CCC(C)C)c2=O)s1 +N#Cc1c(F)cccc1N1CCN(Cc2cccc(O)c2)CC1 +CC(C)Cc1nc(C(=O)NCC(=O)N(C)C)cs1 +CCOC(=O)c1csc(NC(=O)c2cnc3ccc(C)cn23)n1 +COC(=O)NCc1ccc(NC(=O)c2cn(C)nc2C(C)(C)C)cc1 +CC(O)C(=O)N1CCN(Cc2cnc3ccc(C#N)cn23)CC1 +CC(C)(C)C1CCc2nc(NC(=O)NCc3ccccn3)ncc2C1 +COc1c(Cl)cc(C(=O)NCCCN2CCCC2=O)cc1Cl +CC(C)NC(=O)N1CCC2(CC1)COCCN(Cc1cccnc1)C2 +COCc1ccccc1NC(=O)N1CC(C)OC(c2ccccc2)C1 +O=C(Nc1ccc(-c2ncccn2)cc1)c1ccc2c(c1)OCCCO2 +O=C(Nc1ccccc1-n1cccn1)c1ccccn1 +COc1ccc(C)cc1C(C#N)C(=O)c1ccoc1 +COCC(C#N)NC(=O)c1cc(C(C)C)nc2c1cnn2C(C)C +Cc1cc(NC(=O)C2CC(=O)N(c3cccc(C)c3C)C2)no1 +CCS(=O)(=O)c1ccc(C(=O)C2CCC2)cc1 +Cc1cc(C)n(CCCNC(=O)C(c2ccccc2F)N(C)C)n1 +O=C(Nc1cc(N2CCOCC2)ncn1)c1ccc(-n2cccc2)cc1 +Nc1nc2c(cc1C(=O)N1CCc3ccccc31)CCCCC2 +Cc1ccccc1OCC(=O)NCCc1nnc(-c2ccccc2)o1 +C#CCCNC(=O)COc1ccc2ccccc2c1 +O=C(c1cc(-c2ccccc2)on1)N1CCc2sccc2C1 +COC(=O)N1CCC(NC(=O)c2ccc(-c3ccccc3F)o2)CC1 +CC(C)(C)CC(=O)NCCNC(=O)c1ccccc1O +c1cnn(C2CCCN(Cc3cnc(N4CCOCC4)nc3)C2)c1 +Cc1ccc(C(C)NC(=O)N2CCCCC2C)o1 +O=C(Nc1nncs1)c1cc(Cl)c2c(c1)OCO2 +CC(C)(C)C(=O)NCc1ccc(OC(F)F)cc1 +CC(C)N(C)C(=O)NCCS(=O)(=O)NCC1CCC1 +Cc1nnc2n1CCN(Cc1cc(Cl)c3c(c1)OCCO3)C2 +O=C(NCCCc1nc2ccccc2[nH]1)c1cccnc1 +Cc1ccc(C)c(C(=O)CCC(=O)N2CCCC(O)C2)c1 +Cc1ccc(S(=O)(=O)N(C)C(C#N)c2ccco2)c(C)c1 +CCOC(=O)C(C)NS(=O)(=O)c1ccc(CC)s1 +COc1ccc(-c2nc(Cn3cnc(C(C)=O)n3)c(C)o2)c(C)c1C +Cc1cnn(CC2CCCN2Cc2nnnn2C2CC2)c1 +CC(C)(C)c1nnc(SCC(=O)NC(C)(C#N)C2CC2)n1N +COc1ccc(OCC(=O)NC2CCCCC2)c(N)c1 +Cc1nc(C(F)(F)F)ccc1NC(=O)NCc1ccccc1 +CC(C)c1c(C(=O)N(C)C)cnn1-c1cccc(Cl)c1 +Cc1ccc(-n2ccnc2S(C)(=O)=O)cc1C +CCc1nc(CC)n(CC(=O)Nc2ccc(C(C)=O)cc2)n1 +CC(C)Oc1ccccc1NC(=O)c1scnc1C1CC1 +O=C(CC1C=CCC1)NCc1cccc2cccnc12 +Cc1cc(C)n(S(=O)(=O)c2cc(C)c(Cl)cc2C)n1 +Cc1ccc(C)c(-c2nc(-c3ccccn3)no2)c1 +Cc1n[nH]c(=O)nc1Nc1ccc(OC(F)(F)F)cc1 +NC(=O)Cn1c(CCc2ccccc2)nc2c(N)cccc21 +CC1CCC(NC(=O)c2cc(-c3cccs3)on2)CC1 +CN1C(=O)CCC(C(=O)NC2CCCC2)C1c1cccs1 +CC(C)C(NC(=O)c1cnccc1Cl)c1nnc2ccccn12 +Cc1nn(C)c(C)c1NC(=O)CCCC1CCCCC1 +CN(C)S(=O)(=O)N(C)C(C#N)c1cccc(Cl)c1 +CCc1ccc(NC(=O)C2CC(=O)N=C(N3CCN(C)CC3)N2)cc1 +Cc1ccc(-c2nc(C)c(C(=O)N(C)Cc3ccc(O)cc3)s2)o1 +COc1ccc(C(C#N)N(C)C)cc1Br +CCOC(=O)CSc1nc(N)c(C#N)c(CC(C)C)c1C#N +COc1ccc(-c2csc(CNC(=O)c3cc(C)oc3C)n2)cc1 +COc1cc(C2NC(=O)c3ccccc3N2)ccc1OC(C)=O +O=C(Cc1cn2ccsc2n1)NC1(c2ccc(Cl)cc2)CC1 +Cn1cn[nH]c1=NC(=O)COc1ccccc1F +Nc1cccc2c1CCN2C(=O)CCOc1ccccc1 +O=C(c1ccncc1F)N(Cc1ccccc1C(F)(F)F)C1CC1 +Cc1cccc(NCCC(O)c2ccc3c(c2)OCCO3)c1 +COC(=O)c1cn(-c2ccccc2)c(C)c1C(=O)OC +Cc1n[nH]c(-c2cccc(CNC(=O)CCc3ccc(F)cc3)c2)n1 +CCNC(=O)CCCC(O)c1ccc(OC)c(Cl)c1 +O=C(CCc1ccc2c(c1)OCO2)Nc1cccc(-c2nnco2)c1 +COc1ccc(C(C)C)cc1S(=O)(=O)Nc1cccc(C)n1 +CC(C)CNC(=O)C(N)c1c(F)cccc1Cl +Cc1ccccc1NC(=O)Cc1cccc(OCC#N)c1 +COC(C)C(=O)Nc1ccccc1Cc1ccccc1 +COc1ccc(-c2c3c(=O)n(CCO)ccc3nc3ncnn23)cc1 +Cc1nc(N2CCCC2)nc(C)c1NC(=O)C(C)(C)C +Cc1ccc(C)c(C(=O)CCC(=O)Nc2ccc(C(N)=O)cc2)c1 +CC1CCc2[nH]c(=O)c(C(=O)Nc3ccccc3C#N)cc2C1 +N#Cc1ccc(Cn2c(C3CC3)nc3cccnc32)cc1 +CCC(=O)NC(CN1CCCC1=O)c1cccc(C(F)(F)F)c1 +O=C(Nc1cccc(Cl)c1)Nc1ccc2c(c1)C(=O)NCC2 +Cc1ccc(C(C)NC(=O)Cn2c(=O)cnc3ccccc32)o1 +CCN(Cc1ccccc1)C(=O)COC(=O)c1cccc2ncccc12 +CC(Nc1cnn(C(C)(C)C)c1)C(=O)NCC(F)(F)F +CCOc1ccc(C(=O)NCCS(N)(=O)=O)cc1 +N#Cc1ccnc(SCC(=O)c2cc(F)ccc2F)c1 +O=C(NCc1nnc2ccccn12)c1ccsc1 +Cn1nc(-c2ccccc2)cc(C(N)c2ccccc2)c1=O +NC(=O)c1cnc(NCC2CCN(c3ccccc3)C2)c(Cl)c1 +COc1ccc(Br)cc1NC(=O)NCC1CCCCO1 +O=C(NCC(O)c1ccccc1C(F)(F)F)c1ccco1 +COc1ccc(C(=O)N2CCN(C(=O)c3cnc[nH]c3=O)CC2)cc1 +CC(C)c1nccn1-c1cccc(C2CCCN2c2ncccn2)n1 +CCNc1ncnc2sc(C(=O)N3CCCCC3C)c(C)c12 +CC1CCC(NC(=O)c2cnc3c(cnn3C(C)C)c2)CC1 +Nc1[nH]nc(-c2ccco2)c1-c1nc2ccccc2s1 +O=C(NC1CCCC1)c1cccc(N2C(=O)CCS2(=O)=O)c1 +O=C(NCCc1csc(-c2ccncc2)n1)c1cccs1 +CC1=C(C(=O)OCc2ccccc2)C(c2ccccn2)n2ncnc2N1 +COc1cc(Cc2nc(-c3ccncc3)no2)ccc1C +O=C1CCCN1CCCNC(=O)N1CCN(c2cnccn2)CC1 +NS(=O)(=O)C1C=CN=C(C(F)(F)F)C1OC1CC1 +CC(O)c1cnn(Cc2ccc(F)c(Br)c2)c1 +Cc1ccc(S(=O)(=O)NCCC(C)(C)C)cc1C(N)=O +CC1CCC(N(C)C(=O)Cn2cc(Br)cn2)CC1 +CS(=O)(=O)Nc1ccccc1NC(=O)COc1ccccc1 +COc1cc(CNc2ccc(O)cc2F)ccc1F +O=C(Cn1cc(-c2ccccc2)nn1)NC(CO)c1ccccc1 +Cc1ccc(C(=O)NCc2ccco2)cc1NC(=O)c1cccs1 +NS(=O)(=O)CCNC(=O)c1cccc(-n2cccc2)c1 +CC(C)N(CCCO)C(=O)c1ccc(N(C)C)nc1 +COc1cccc(NC2CCN(C(=O)Nc3cccnc3)CC2)c1 +CCn1cc(C(=O)NCCCc2cnn(C)c2)cn1 +COc1ccc(C(=O)N2CCCC(CNC(=O)C(C)(C)C)C2)c(O)c1 +Nc1nonc1-c1nnc(C=Cc2ccc(O)cc2)o1 +CCc1ccc(C(=O)OCc2sc(C)nc2C)o1 +COC(=O)c1cc(Cl)c2nc(OC)nc(N)c2n1 +Cn1c(=O)c(=O)n(CC(=O)N2CCOCC2)c2ccccc21 +Cc1cnn(CC2CCCN2C(=O)c2cc[nH]n2)c1 +CN(Cc1ccc(F)cc1)S(=O)(=O)c1ccccc1C#N +CCN(CCC(=O)OC)C(=O)c1ccccc1Cl +C#Cc1cccc(NC(=O)CN(C)S(=O)(=O)N(C)C)c1 +CCOC(=O)c1nn(Cc2ccc(C(=O)OC)cc2)c(N)c1C#N +Cc1noc(CNCc2c(C)nc3scc(C)n23)n1 +O=C(Nc1n[nH]c(-c2ccco2)n1)c1ccccc1Br +C#CCN1C(=O)C(Cc2ccc(Cl)cc2)Oc2ccc(N)cc21 +O=C(c1cc(Cl)ccn1)N1CC=C(c2ccccc2)CC1 +Cc1[nH]c2ccnn2c(=O)c1Cc1cccc(Cl)c1 +Cc1cc(NC(=O)N(CC(O)c2ccc(F)cc2)C2CC2)no1 +COC(=O)CNC(=O)c1cc(Br)ccc1OC(F)F +CC1CC1C(=O)OCC(=O)NCCSc1ccc(Cl)cc1 +CC(c1ccccn1)N(C)Cc1csc(-c2ccsc2)n1 +Cc1nc(N(C)C)ncc1C(=O)NC1CCCCCC1 +Cc1c(-c2csc(-c3cnccn3)n2)oc2ccccc12 +O=C(Nc1ccc(F)cc1)c1ccc(NC(=O)N2CCOCC2)cc1 +O=C(Cc1cc(Cl)c2c(c1)OCCO2)NCCc1ccc(F)cc1 +Cc1ccccc1-c1noc(CNc2ccc(F)cc2OCCO)n1 +O=C(Oc1ccc2ccccc2c1)C1CCCN1C(=O)C1CC1 +COc1cc(-c2cn3cccc(N)c3n2)cc(OC)c1OC +CCCNC(=O)c1nnc2c(C(=O)NC)ncn2c1N +CCC(=O)N1CCCCC1C(=O)N(Cc1ccccc1)CC1CCC1 +Cc1nc(-c2cccnc2)[nH]c(=O)c1CC(=O)NCc1ccsc1 +COc1cc(C2c3c(C)n[nH]c3C(=O)N2c2ccc(C)cc2)ccc1O +CCCN(CCC)c1ncc(N)cc1Br +Cc1noc(COCC(=O)Nc2cc(C(=O)N(C)C)ccc2C)n1 +Cc1cc(C)n2nc(CC(=O)N3CCCC3c3noc(C)n3)nc2n1 +CCOC(=O)c1csc(NC(=O)CSc2ccccc2)n1 +Cc1cc(S(N)(=O)=O)cc(Br)c1C +COc1ccnc(NC(=O)c2cc3cccc(Br)c3o2)c1 +COc1ccc(C(=O)CCC(=O)NC2CC2)cc1F +Cc1nnc(N2CCC(NC(=O)C3CCCCC3)CC2)c(C#N)c1C +Cc1ccc(-c2ncc(F)c(NCCO)n2)c2cccnc12 +COc1ccc2oc(C)c(C(=O)N3CCN(C(=O)CO)CC3)c2c1 +CCOCCn1c(CNC(=O)c2ccco2)nc2ccccc21 +Cc1cc(C)cc(NC(=O)c2c(C)nc3ccccn23)c1 +CC(=O)NCC(=O)NC(C)Cc1c(Cl)cccc1Cl +Nc1cccc(-c2nnc(-c3ccc4nc[nH]c4c3)o2)c1 +CS(=O)(=O)c1ccc(C(=O)N(Cc2cccs2)C2CC2)cc1 +CCS(=O)(=O)c1noc(C(=O)NC2CCCCC2)c1N +Cc1ccc(Cl)c(OCC(=O)c2ccn(C)c2)c1 +Cc1ccc2nc(NC(=O)CNC(=O)c3cccs3)sc2c1 +CNC(=O)C(C)CN(C)C(=O)Nc1ccc2c(c1)COC2 +Cc1cc(C)cc(OCn2ccc(C(=O)NCC(=O)C(C)(C)C)n2)c1 +Cc1n[nH]c(C)c1NC(=O)Nc1ccccc1C(=O)N1CCCCC1 +COc1ccc(-c2nnc(SCc3ccccc3C#N)n2N)cc1 +Cc1ccc(C)c(NC(=O)CCn2cnc3ccccc32)c1 +Cc1nn(C)c(=O)c(C(=O)Oc2cccc(Cl)c2Cl)c1C +CCCOC1CCCN(C(=O)c2cc(NC(C)=O)ccc2F)CC1 +CNC(=O)NCC(=O)N1CCN(C(=O)Cc2ccc(C)cc2)CC1 +COc1cccc(C(=O)N(C)CC(=O)N(C)C)c1F +Cc1cc(CNC(=O)C2CCC(=O)N(C3CCCCCC3)C2)on1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)CN1CCOC1=O +CC(C)Cc1ccc(S(=O)(=O)N2CCN(CCO)CC2)cc1 +Cc1noc(C2CCCN(C(=O)NCCc3ccccc3)C2)n1 +CC(C)c1nc(S(=O)(=O)N2CCSc3ccccc32)c[nH]1 +CC(c1ccccc1)N1CC(C(=O)NC2CC2)CC1=O +COc1c(C(=O)Nc2cccc(C)n2)nnn1Cc1ccc(C)cc1 +CCCC(C)NC(=O)Cn1cc(C(=O)NC)ccc1=O +O=C(Cn1ccnc1)N1c2ccccc2NC(=O)C12CCCC2 +CCc1nc(N2CCOCC2)c2c3c(sc2n1)CCC3 +CCCNC(=O)CNC(=O)c1cccc(NC)n1 +Cc1nc(CC(=O)N(C)CC(=O)Nc2c(C)cccc2C)cs1 +CCCn1c(CN2CCC(OC(C)=O)CC2)nc2ccccc21 +CC(=O)NC(C(=O)Nc1ccc(OC(F)F)c(Cl)c1)C(C)C +O=C(NCCCN1CCOCC1)C1(c2ccccc2)CC1 +Cn1cc(C(=O)NCc2ccccc2Cl)c(=O)c2ccccc21 +COc1cc(CNC(=O)NC(C)C(C)C)ccc1C +CCCn1cc(NCc2cnc3ncccn23)cn1 +CC12CCC(c3nc(-c4cccnc4)no3)(OC1=O)C2(C)C +CC1(C(=O)N2CCN(C(=O)c3ccccc3)CC2)CC1(Cl)Cl +COC(=O)CCC(=O)NC1CCCCC1Cc1ccccc1 +CN(Cc1ccco1)c1ncc(N)cc1Br +COc1ccccc1Nc1nc(C(=O)NCC(=O)NC2CC2)cs1 +CC(C)n1cnnc1CN(C)Cc1cc2c(cc1Cl)OCO2 +CCC(C(=O)OCc1ccccc1)n1nnc(C(C)=O)c1C +Cc1occc1C(=O)Nc1ccc(F)cc1Cl +CCc1cccc(NC(=O)Cn2nc(C)nc2C)c1 +COc1ccc(CNC(=O)Nc2cn[nH]c2)c(OC)c1 +COC(=O)c1ccsc1NC(=O)c1cccc(-c2ccoc2)c1 +CCCS(=O)(=O)NCC(C)(O)c1cccs1 +COc1ccc(-c2nnc3sc(C4CC4)nn23)cc1 +CCN(C(=O)Cn1cnc(N)n1)c1ccccc1C +CNC(=O)c1cn(C2CCCCC2)cc(C(=O)NCCC(C)C)c1=O +COc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1Cl +CN(C(=O)C1CCCOC1)c1ncccc1Br +Cc1cc(C)c(CNC(=O)Nc2nnc(C)s2)c(C)c1 +O=C(C1CC1)N1CCN(Cc2cc(-c3ccccc3)no2)CC1 +Cc1ccc(C(=O)Nc2cnc3c(cnn3C(C)C)c2)cc1F +CCc1nn2c(C#N)c(-c3cc(C)cc(C)c3OC)nc2s1 +Cn1cnc(CNC(=O)NC(c2cc(F)ccc2F)C2CC2)n1 +COc1ccc(Cc2nc(-c3ccco3)cs2)cc1N +CC(C)NC(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +Cc1nn(C)c2cnn(CC(=O)NCc3ccc4c(c3)OCO4)c12 +COc1nc(N2CCOCC2)nc(N2CCC(C)CC2)n1 +O=C(Nc1cnccc1Cl)c1ccc(OCC(F)(F)F)nc1 +COc1ccc(C(=O)N(C)C(C)CC(C)C)c(O)c1 +C=C(C)CN1C(=O)C(C)(C)S(=O)(=O)c2ccc(N)cc21 +CC(NS(=O)(=O)N1CCCCC1C)C1CCCO1 +Cc1cccnc1NC(=O)c1snc(-c2ccccc2)c1N +OC(CNCc1ccccc1F)c1c(F)cccc1F +Cc1nc(-c2ccccc2)c(C(=O)NC(C)CCc2ccco2)s1 +CC(=O)c1cccc(S(=O)(=O)N(CCO)C(C)C)c1 +O=C(Nc1cn[nH]c1)N1CCN(c2cnccn2)CC1 +O=C1NC(c2csc(-c3cccs3)n2)Nc2ncccc21 +Cc1ccc(Cn2ccn(-c3ccccc3C)c(=O)c2=O)cc1 +CN(Cc1ccc(C#N)cc1)C(=O)c1cc(Cl)ccn1 +Cc1cc(CNC(=O)C(C)N2CCCC2=O)on1 +C#CCOc1ccccc1CNC(C)C(=O)N(C)C +Cc1c(C(=O)NCc2cccs2)nc2c(Cl)cccn12 +c1cc(Cn2ccnc2)cc(NC2CCOCC2)c1 +CCC(NC(=O)c1cccc(Cl)c1)c1ccccc1 +CCOc1cc(C(=O)N2CCCCCC2)ccc1OC +Cc1cc(C)n2nc(C(=O)Nc3ccccc3Cl)nc2n1 +CCCOc1ccc(S(=O)(=O)n2ccnc2C)c2ccccc12 +O=C(c1ccc(F)cc1F)N1CCc2sccc2C1 +C=C(C)Cc1c(C)nn(S(=O)(=O)c2ccccc2)c1O +O=C(c1ccc(F)cc1)c1c[nH]c2c(Cl)cccc2c1=O +FC(F)(F)c1nnc2ccc(N3CCOCC3)nn12 +NC(=O)c1ccc(S(=O)(=O)NCCC2=CCCCC2)cc1 +CCNC(=O)C1CCN(c2ccccc2-c2ccccc2)C1=O +CCNC(=O)CSc1nccn1-c1cccc(Cl)c1 +Cc1sc(C(=O)NCCC(=O)N(C)C)cc1-c1ccc(F)cc1 +CC(=O)N1CCCN(C(=O)c2ccc(C)nc2)CC1 +N#Cc1ccc(OCCNc2ccccc2C(=O)N2CCCCC2)cc1 +Nc1cccc(NC(=O)COCCOc2ccccc2)c1 +Nc1ccc2c(c1)CCCN2C(=O)Cc1cccs1 +O=C(Nc1cc2c(cc1Cl)OCCO2)NC(C1CC1)C1CC1 +COc1ccc(C(C#N)NCc2ccccc2)cc1 +N#Cc1ccc(-c2noc(C3C4CCCCC43)n2)nc1 +COc1cc(C)ccc1NC(=O)c1ccccc1-n1cccn1 +O=S(=O)(N1CCCCC1)N1CC2(CC2)c2ccccc21 +CCc1noc(C(C)N2CCc3ccccc3C2)n1 +O=C1CCC(NC(=O)c2ccc3c(c2)CCO3)CC1 +O=C(Nc1nc(-c2ccco2)n[nH]1)C1CCCCC1 +Cc1cc2c(c(C(=O)c3ccncc3)c1)OCCCC2 +O=C(CNc1ccc(Cl)cc1)N1CCOCC1 +N#Cc1c(N)nc(C(=O)c2ccccc2)c(C#N)c1N +CC(Oc1ccccc1Br)C(=O)Nc1ncccn1 +CC1CN(C(=O)c2cnc3n(c2=O)CCS3)CC(C)O1 +O=S(=O)(NCC1CC2CCC1C2)c1ccccc1 +CNC(=O)COc1ccc(NC(=O)c2cccc(OC)c2F)cc1 +Cc1csc(C(C)N(C)C(=O)c2ccc(CCC(C)(C)O)cc2)n1 +CC=CCOC(=O)Cc1c(C)nn(-c2nc(C)cc(C)n2)c1C +CC(=O)NCCNc1nc2cc3c(cc2cc1C#N)OCO3 +CC(C)c1nc(CNc2cccc(OCC(F)(F)F)c2)no1 +COc1ccc(CN2CC(C)OCC2C)cc1OCCCC#N +Nc1nnc(SCc2ccccc2)n1CC(=O)Nc1ccccc1 +COC(=O)c1ncn(CCOc2ccccc2Br)n1 +Cc1cccc(NC(=O)CCCNC(=O)c2cccs2)c1C +COCCNC(=O)N1CCN(CC(=O)N2CCCCC2)CC1 +Cc1ccc(C)c(C(=O)c2ccccc2C(=O)Nc2cn[nH]c2)c1 +CC(Cc1ccc(O)cc1)NC(=O)c1cn(C)nc1C(C)(C)C +CC(C)c1c(CO)nnn1CCCOc1ccccc1 +Cc1ccc(O)c(C(=O)N(C)CC(O)COCc2ccccc2)c1 +CCOc1ccc(C(=O)N(C)CC(=O)N2CCOCC2)cc1 +Cc1ccc(-c2nnc3ccc(N4CCCC4)nn23)cc1 +COCc1ccccc1CNC(=O)Nc1cccc(N(C)C(C)C)c1 +O=C(OCC1CC1(Cl)Cl)c1scnc1C1CC1 +CCOC(=O)CCC(=O)Nc1ccc(Cl)c(Cl)c1 +CC(C)(C)OC(=O)N1CCCC1C(=O)OCc1nc2ccccc2[nH]1 +CS(=O)(=O)c1cccc(C(=O)N2CCCC2Cn2cccn2)c1 +CCOc1ncnc2c1CCN(c1cc(C(F)(F)F)ncn1)CC2 +Cn1c(CCNC(=O)c2ccc(F)c(Cl)c2)nc2cc(N)ccc21 +Cn1ncc2c(SCc3nc(Cc4ccccc4)no3)ncnc21 +Fc1ccc(-c2n[nH]cc2-c2ccc3nccn3c2)cc1 +Cc1[nH]c2ccccc2c1C(=O)NC1C=CC(CO)C1 +Cn1ncc(C(=O)OCc2cccc(C(N)=O)c2)c1-n1cccc1 +O=C(c1ccc(-c2nc(C3CC3)no2)cc1)N1CCOCC1C1CC1 +O=C(Nc1ccc2c(c1)C(=O)CCC2)NC1C2CCOC2C12CCC2 +Cc1ccsc1C(=O)Nc1cnn(CC2CC2)c1 +CCN(CC)C(=O)C(C)C1(O)c2ccccc2Oc2ccccc21 +COc1ccc(N)cc1OCCN1CCOCC1 +COCCn1cnnc1CCNC(=O)Nc1cccn2cnnc12 +CC(C)C(O)C1NCCc2cc(C(F)(F)F)c(F)cc21 +CC(C)Cc1nc2cc(Cl)cnc2n1CCCO +Cc1ccnc(OCC(=O)Nc2cccc(F)c2)n1 +Cc1cc(OCC(=O)Nc2cccnc2)c2c(C)cc(=O)oc2c1 +Cc1nn(C)c(=O)c(C(=O)Nc2ccc(OC3CCCC3)cc2)c1C +CCC(C)NC(=O)CCNC(=O)c1cnn(-c2ccncc2)c1C +CCOC(=O)CCC(=O)c1ccc(OC)c(C)c1 +O=C(CCOc1ccccc1)NCc1cscn1 +COC(=O)C(NC(=O)c1cc(C)ncn1)c1ccc(Cl)c(F)c1 +CC(C)c1csc(C2CCCN(C(=O)C3CCC(=O)N3)C2)n1 +N#CCC1CCCOc2ccc(Br)cc21 +CC(C)Cc1ccc(S(=O)(=O)NC(C)C#N)cc1 +Cc1cnc(CNc2nc3ccccc3n3c(C)ncc23)cn1 +O=C(Nc1ccc(-n2cccn2)cc1)c1cc(-c2ccccc2)on1 +COc1cc(N)ccc1NC(=O)c1cccc(Cl)c1 +Cc1cccc(C(=O)NC(C)c2cccc(N3CCOC3=O)c2)n1 +COc1sc(CN2CCC3(C2)OCCO3)cc1Br +O=C(Nc1ccc(-c2csnn2)cc1)c1ccnc(-n2ccnc2)c1 +Cc1cc(C)cc(N2CCC(C(=O)N(C)CC3CCCCO3)C2=O)c1 +CCOC(=O)C1CC(F)CN(C(=O)OC(C)(C)C)C1 +Cc1ccc(OCCc2nc(CCO)c(C)o2)cc1 +CCCNS(=O)(=O)c1ccc(OC(F)F)c(Cl)c1 +COc1ccccc1CN(C)C(=O)CCc1cnn(-c2ccccc2)c1 +O=C(NC1CC1c1cccc(Cl)c1)N1CCOCC1 +C=CCN(CC(F)(F)F)C(=O)c1ccc(C(N)=O)nc1 +Cc1csc(N2CCN(CC(=O)NC(C)c3ccco3)CC2C)n1 +CCOc1ccc(C(=O)N(C)CC)cc1OCC +Cc1cc(C#N)c(NCc2ccc(F)c(C)c2)s1 +COc1ccc(NC(=O)CSc2nc(C)c(C)c(C)n2)cc1OC +O=C(NCC1CCCO1)c1cccc(N2C(=O)CCS2(=O)=O)c1 +CC(=O)Nc1sc2c(c1C(=O)Nc1cccc(Cl)c1)CCC2 +Cc1c(C(=O)N(C)C(C)C)cnn1-c1cccc(C(F)(F)F)c1 +CCCn1ccnc1-c1nccn1-c1cccc(-c2ccnc(C)n2)c1 +CCc1ccc(C(=O)NCCNC(=O)C(C)C)cc1 +O=C(Nc1cnn(CC(F)F)c1)c1scnc1C1CC1 +C#CCN1CCC(C(=O)NCCNC(=O)C2CC2)CC1 +Cc1nn2cc(C(=O)NCc3cccc(C(F)(F)F)c3)nc2s1 +Cc1cccc(C)c1-n1nnc(-c2ccncc2)c1N +O=C(CCc1nc(-c2ccsc2)no1)Nc1ccc(F)cc1F +COC(=O)NCCC(=O)N(Cc1cccs1)c1ccc(F)cc1 +CCNC(=O)c1ccc(NC(=O)CCSc2ccc(C)cc2)cc1 +CCc1ccccc1NC(=O)CNc1ccccc1N1CCCC1=O +CCc1noc(CC)c1CC(=O)N(C)Cc1nccn1C(F)F +Cc1nc(SCc2nnc(-c3ccccc3)o2)c2ccccc2n1 +CCCc1ccc(C(O)CCN2CC(C)OC(C)C2)cc1 +COCCCNC(=O)CS(=O)c1ccccc1N +CN1CCC(NC(=O)NCc2cc(C#N)ccc2F)C1=O +CN1CC(NC(=O)C2(C)CC2(Cl)Cl)CCC1=O +O=C(OC1CCOC1=O)c1csc(-c2cccs2)n1 +CC(NC(=O)Nc1ccccc1)c1ccc(NC(N)=O)cc1 +COCc1nc(COc2cccc(C)c2C)sc1C#N +CN(C(=O)c1ccc(C#N)cc1)c1nc2ccccc2s1 +CC1CCOC1C(=O)N1CCC(NC(=O)CCc2ccccc2)CC1 +Cc1sc2ncn(CC(=O)N(C)Cc3ccsc3)c(=O)c2c1C +CC(Cc1ccccc1F)NC(=O)N1CCOCC1C1CC1 +CCN1C(=O)COC2CN(C(=O)c3cnc4ccccc4c3)CC21 +COCC(=O)Nc1ccc(NC(C)(C)CO)nc1 +CCn1c2ccccc2n2c(S(=O)(=O)Cc3ccccc3)nnc12 +CC(NC(=O)c1ccccc1)C(=O)NC(C#N)C(C)(C)C +CCN(Cc1ccccc1)Cc1cc(=O)c(O)cn1CC(C)C +C=CCNS(=O)(=O)c1ccc2c(c1)CNCC2 +CCCn1c(SCC(=O)Nc2sccc2C#N)nnc1C1CC1 +CN(Cc1cnn(C)c1)S(=O)(=O)c1c(Cl)cccc1Cl +COc1ccc(CNC(=O)NC(C)CO)cc1OC(F)F +O=C1Nc2ccc(Cl)cc2C1Nc1cccnc1 +CCOc1ccc(C(C)NC(=O)Nc2ccc(C#N)cc2)cc1OC +Cc1ncc(C(=O)NCc2nc(Cc3cccs3)no2)c(=O)[nH]1 +CNC(=O)C1CCN(C(=O)c2n[nH]c(N)n2)CC1 +C=CCN(CC=C)C(=O)CN1CC(C)c2ccccc21 +COc1ccccc1CNC(=O)c1cn2cccc(C)c2n1 +CC(NC(=O)c1cn[nH]c1)c1nc2ccccc2[nH]1 +CNS(=O)(=O)c1ccc(C(=O)N(C)C2CCCCC2C)o1 +CCNC(=O)CSc1nncn1-c1ccc(C)cc1C +CCN(CCNC(=O)Nc1nnc(C2CC2)s1)c1ccccc1C +CCC(C)NC(=O)c1cc(C2CC2)nc2c1c(C)nn2C +Cc1cc(C(=O)N2CCOC(C(N)=O)C2)c(C)n1C(C)C +COc1ccc(C(=O)C2CCN(C(=O)c3ccccc3)CC2)cc1 +CCNC(=O)CNC(=O)COc1ccc(Cl)cc1 +COC(=O)CCN(C)C(=O)C(C)Oc1ccc(Cl)cc1Cl +NC(=O)c1ccc(OS(=O)(=O)c2ccccc2F)cc1 +Cc1nnc2n1CCN(C(=O)Cc1cnn(-c3ccccc3)c1)C2 +COc1ccc(C)cc1CCNC(=O)Nc1cc(C)on1 +Cn1cccc1C1COCCN1C(=O)CCc1c[nH]c2ccccc12 +CCc1ccc(CC2(c3ccc(OC)cc3)NC(N)=NC2=O)cc1 +COCC(C)(O)CNS(=O)(=O)Cc1cccc(Cl)c1 +COc1cccc2c(O)cc(C(=O)NC3CC3)cc12 +COC(=O)CN(C(=O)c1c[nH]c(=O)cn1)C(C)C +CC(O)c1ccc(Oc2ccc(CC#N)cc2)cc1 +COc1ccc(F)cc1NC(=O)NCc1nc(C(F)(F)F)cs1 +Fc1ccccc1OC1OCCOC1Oc1ccccc1F +CCS(=O)(=O)N1CCC(NC(=O)c2cccc(N(C)C)c2)CC1 +N#Cc1cn(Cc2nnnn2C2CC2)c2ccc(Cl)cc2c1=O +CCCC1CN(C(=O)Nc2ccc(OC)c(F)c2)CCO1 +O=C(NC1CC1)c1cc2cc(Cl)ccc2oc1=O +C(=Cc1cccs1)c1nc2sc3c(n2n1)CCNC3 +O=C(Cc1noc2ccccc12)Nc1cccc(-c2ccn[nH]2)c1 +Cc1ccc(C)c(S(=O)(=O)NC(C)c2ccc(N)cc2)c1 +Cc1cnc(C(=O)N2C3CCC2Cc2c(nc(C)[nH]c2=O)C3)cn1 +O=C(CCCn1nnc(-c2ccccc2)n1)N1CCC(O)C1 +O=C(Cc1cccc(F)c1)Nc1cccn(Cc2ccccc2)c1=O +CCOCC(=O)N1CCC(c2cc(C(C)C)n[nH]2)CC1 +N#CCOc1cccc(CC(=O)Nc2ccc(F)cc2F)c1 +COc1cccc(C)c1NCc1cccc(C#N)c1 +Cc1cc(NC(=O)C(C)OCC(F)(F)F)no1 +NC(=O)C(NC(=O)Cc1ccc(-n2cccn2)cc1)c1ccccc1 +CCCCNc1ncnc(NC2CCCCCC2)c1N +COc1ccc(C2(C(=O)NCCCO)CC2(C)C)cc1 +CC(=O)N1CCC(C(=O)Nc2nnc(C)s2)CC1 +OCc1c(-c2ccncc2)nc2sc(-c3ccccc3)nn12 +CCOC(=O)CC(C)CNC(=O)c1oc(C)cc1C +COc1ccc(Cl)cc1-c1cc(NC(=O)c2cc(C)nn2C)[nH]n1 +COc1cc(N)c(C(=O)Nc2ccc(C)cc2C)cc1OC +Cn1cccc1C(O)CNC(=O)c1ccccc1C(F)(F)F +COC(=O)Nc1ccc(CNC(=O)c2sc(C)cc2OC)cc1 +COC(=O)c1sc(-c2cc(OC)ccc2OC)nc1C +CN1C(=O)c2ccccc2N(C)C1c1ccccc1Cl +CCN(CCO)C(=O)CCc1ccc(N2CCC(C)CC2)c(N)c1 +O=C(Nc1ccccc1CN1CCNC1=O)c1cccc(F)c1F +CCC1CCC(CNC(=O)c2c[nH]c(=O)c(Cl)c2)CC1 +COc1ccccc1CC(=O)Nc1ccc(S(N)(=O)=O)cc1 +CN(CCc1cn[nH]c1)C(=O)CCNC(=O)c1ccccc1F +CC(C)Cc1nnc2sc(CCc3nc(-c4ccco4)no3)nn12 +O=C(CSc1cccs1)NCc1cccnc1 +COC1(OC)C=CC(C(=O)c2ccccc2)C(O)(O)C1 +CCCCn1nc(-c2cccc(OCC)c2)cc(C#N)c1=O +Cc1cc(C)cc(C(=O)NCC(=O)OCC(=O)NC2CC2)c1 +CC(NC(=O)CCCN1CCOC1=O)c1cccc(Cl)c1 +CCc1nn2c(CNC(=O)c3cccn3C)c(C)nc2s1 +O=S(=O)(NCCCOC1CCCC1)c1ccc(Cl)cc1 +CN(C)S(=O)(=O)NCCc1ccccc1C(F)(F)F +Cc1ccc2nc(CSc3nnnn3C)cn2c1 +CC(C)Cn1c(C(C)O)nc2ccc(Cl)cc21 +CC=CCOc1nc2c(c(=O)n(C)c(=O)n2C)n1C +CCS(=O)(=O)NCCCNC(=O)c1cc2c(s1)CCC(C)C2 +CCN(C(=O)COC(=O)c1ncsc1NC)c1ccccc1 +Cc1nccc(NC(=O)Cc2cccnc2)c1Cl +N#Cc1cccc(NC(=O)CSc2ccc3c(c2)OCCCO3)c1 +COCc1cccc(C(=O)N2CCC(CC(=O)N3CCCC3)CC2)c1 +CC(=O)c1ccc(F)cc1NC(=O)c1ccnn1C +Cn1cnnc1-c1ccc(NC(=O)C2CCOCC2)cc1 +COc1ccc(-c2nc(C(C)=O)c(C)o2)c(OC)c1 +Cc1nc(N(C)C)ncc1C(=O)N1CCN(c2ccc(F)cc2)CC1 +OCc1cccc(-c2cc(O)cc(C(F)(F)F)c2)c1 +CNC(=O)NCCOC(=O)Nc1cccc2ccccc12 +CC(NC(=O)c1ccncc1Cl)(C(N)=O)c1ccccc1 +CN(CCOc1ccccc1F)Cc1cc(=O)n(C)c(=O)n1C +CC(C)CN(CC(F)(F)F)C(=O)Cn1ccc(N)n1 +Cc1ccccc1NC(=O)C1CNc2ccccc2O1 +CC(=O)c1c(C)nn(S(=O)(=O)c2c(C)cc(C)cc2C)c1C +Cc1ccc(C(=O)N(C)C2(C#N)CCC2)cc1NC(=O)c1ccccc1 +Nc1c(-c2ccc(F)cc2)nnn1-c1ccccc1F +Cc1cc(C)n(C2CCN(c3ncccn3)CC2)n1 +CCc1c(CO)nnn1-c1ccc(C)c(Br)c1 +Cc1noc(C)c1CCC(=O)NC(C)c1nnc2n1CCC2 +CS(=O)(=O)c1cccc(NC(=O)c2occc2-c2ccccc2)c1 +O=C(NC1CCCCCC1)C1CN(C(=O)c2c[nH]c3ccccc23)C1 +Fc1cc2c(cc1Cl)C(c1nccs1)NCC2 +Cc1nc(C)c(CC(=O)Nc2ccc3oc(C)nc3c2)c(=O)[nH]1 +CC(C)(C)C(O)CCNC(=O)C1CC(=O)N(c2ccccc2)C1 +Cc1cc(C)c(NC(=O)CNC(=O)CN2CCCCCC2=O)c(C)c1 +CCN(CC(C)C#N)C(=O)CN1CCCSc2ccccc21 +Cc1noc(COC(=O)CCc2ncc(-c3ccc(Cl)cc3)o2)n1 +CCOCCNS(=O)(=O)c1ccc(C)cc1C +O=C(Nc1ccc2c(c1)COC2)c1cccc(Nc2cnccn2)c1 +COc1cc(NC(=O)CSc2nnns2)cc(OC)c1 +CCN(C)c1ccccc1NC(=O)Nc1cccc(NC(C)=O)c1 +O=C1CN(C(=O)C2CCN(C(=O)Nc3cccs3)CC2)CCN1 +CCN(CC)C(=O)Nc1nnc(C(C)(C)c2ccccc2)s1 +O=c1c(=O)c2cccc3c2-c2c1cccc2c(=O)c3=O +CCOc1ccc(OCC(O)Cn2cnc3sccc3c2=O)cc1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)Nc1nnc(C(C)C)s1 +Cc1cccc(CNC(=O)CNC(=O)c2cc(C)n(C)n2)c1 +O=C(CNc1c(F)cccc1F)N1CCOCC1 +N#Cc1c(-c2nc3ccccc3s2)c(=O)oc2cc(O)ccc12 +O=C(NCCn1ccnc1-c1ccc2occc2c1)c1ccncc1 +O=C(NCc1nncn1-c1ccccc1)c1ccccc1 +COc1ccccc1S(=O)(=O)NCC(C)(O)c1cccs1 +CN(C)c1cc(C(=O)NCc2nnc3n2CCCCC3)ccn1 +Cc1cnc2c(c1SCC(N)=O)c(=O)n(C)c(=O)n2C +CC1CN(C(=O)NCCOc2ccc(F)cc2)CCO1 +CCNS(=O)(=O)c1ccccc1NCc1nc(C)no1 +CCCn1ccc2ccc(NC(=O)NCCOC)cc21 +CCOc1ccc(C(C)NC(=O)NCc2csc(C)n2)cc1 +Cc1nc(-c2cccc(F)c2)nc2c1CN(C(=O)C1CCCO1)CC2 +CCc1cccc(C)c1-n1nnc(-c2ccccn2)c1N +CCc1cnc(CNC(=O)N2CCc3ccc(Cl)cc3C2)s1 +Cc1ccc(C(=O)NCCn2nc(-n3ccnc3)ccc2=O)cc1C +Cn1c2sc3c(c2c(=O)n2nnnc12)CCCC3 +N#Cc1cccnc1N1CCN(Cc2cn(-c3ccccc3)nn2)CC1 +CCc1nc(CC(=O)NC2=NC(=O)N(C)CC2)cs1 +CN(C)C(=O)COc1cccc(CNC(=O)Nc2ccc(F)cc2)c1 +Cc1nc2cc(C(=O)NCCOC(C)C)ccc2n1C +CCOC(=O)CC1CSc2ccccc2NC1=O +Cc1ccc(CNC(C)C(=O)N2CCCCC2C)cc1F +COC(C(=O)NCc1c(C)cc(C)[nH]c1=O)c1ccccc1 +COCc1nc(C(=O)NC2CCCCCC2C(=O)OC)cs1 +COC(=O)Cn1ccc(NC(=O)c2cc(SC)ccc2C)n1 +CCN(C)C(=O)c1cnc(-c2cccc(C)c2)nc1N1CCCCC1 +CCN(C(=O)CCNS(=O)(=O)c1ccccc1)c1ccccc1C +CN(C)C(=O)CNC(=O)C1CCC(=O)N1Cc1cccs1 +CC(Oc1cccc(F)c1)C(=O)NCC(O)Cc1ccccc1 +N#Cc1ccc(C2NCCc3c(F)cc(O)cc32)cc1F +CC(=O)N1CCC(NC(=O)Nc2ccc3c(c2)CCC3)CC1 +CC(C)(CC(=O)NCCc1nnc2n1CCCCC2)c1ccccc1 +Cc1ncsc1CN1CCC2(CCCN(C3CCCCC3)C2=O)C1 +CN(C(=O)NCc1ccccn1)C1CCN(c2ccc(F)cc2)CC1 +COc1ccc(F)c(NC(=O)Cc2c(C)[nH]c3ccnn3c2=O)c1 +CC(=O)N1CCC(NC(=O)NCc2cc(C)on2)CC1 +COc1ccc(-c2cnc(COc3ccc(-n4cncn4)cc3)o2)cc1 +Cc1nc(CSc2nnc(N)n2C(C)C)cs1 +Cc1cc(C(=O)OCc2nc(N)nc(N(C)C)n2)c(C)s1 +CC(=O)Nc1cc(C(=O)NC2CCc3c(Cl)cccc32)ccc1F +COC(=O)c1cc(-c2cc(Cl)ccc2SC)nn1CCO +CCCCOc1ccc(C(C)NC(C)=O)cc1OC +COc1ccccc1-n1c(N)c(C#N)c2c(c1=O)COC(C(C)C)C2 +CS(=O)(=O)N1CCN(c2cc(N3CCCC3)ncn2)CC1 +COc1ccc(C(=O)Nc2nc(C)c3c(n2)CCCC3)cc1 +O=C(CNS(=O)(=O)c1cccc2cnccc12)N1CCCC1 +CSc1nnc(SCC(=O)N(C(C)C)C(C)C)s1 +NC(=O)c1ccc(C#CCNC(=O)c2cc(-c3ccccc3)on2)cc1 +COc1ccc(C(=O)N2CCCC2c2ccncc2)cc1 +N#CCCN(Cc1ccco1)C(=O)c1cc2ccccc2o1 +CN(C)C(=O)COC(=O)c1ccc(Cl)cc1O +O=c1cc(N2CCCC2)cnn1CCn1cccc1 +CCn1cc(S(=O)(=O)c2ccc(C)cc2)c(=O)c2cc(C)ccc21 +COC(=O)c1sccc1-n1cc(C#N)c(=O)n(C)c1=O +CCc1ccc(N2CC(C(=O)OCc3ccccn3)CC2=O)cc1 +CCCCN(C)c1ncnc(Nc2ccccc2OC)c1N +O=C(CCNC(=O)c1ccc(Cl)cc1)NC1CCC(O)CC1 +N#CC(CC(=O)N1CCCC1)c1ccc(Cl)c(Cl)c1 +Cc1nc(C(C)(C)NCc2cc(F)c(F)c(F)c2)sc1C +O=C(CCCNC(=O)C1CC1)Nc1cccc2ncccc12 +Cc1noc(C)c1S(=O)(=O)N1CC(OCc2cccc(F)c2)C1 +Cc1ccc(C)c(S(=O)(=O)N(C)c2ccccc2C(N)=O)c1 +N#CC1(C(=O)NCCNS(=O)(=O)c2ccccc2)CCCC1 +CC(=O)Nc1cccc(NC(=O)NCC(C)C)c1C +Cc1c(Cl)cccc1N1C(=O)C(C)CS1(=O)=O +O=C(COc1ccc(Cl)cc1)Nc1ccncc1 +Cc1csc(CN(CC2CCCO2)C(=O)c2cccnc2C)n1 +N#CC(NCCCO)c1cccc(Cl)c1Cl +Cc1ccc(C(O)CNC(=O)c2ccc(Cl)cc2)cc1C +COc1ccc(OC)c(S(=O)(=O)Nc2ccc(Cl)cc2)c1 +Cc1c(C(=O)N2CCC(C)CC2C)cnn1-c1ccccn1 +CCC1CCCC(NC(=O)N2CCN(Cc3nc(C)no3)CC2)C1 +CS(=O)(=O)NCCc1ccc(-c2csc(C3CC3)n2)s1 +CCOC(=O)c1cnn(-c2ccc(C(=O)N(C)C(C)C)cc2)c1C +CCCCCN1C(=O)C(C)Oc2ccc(C(C)=O)cc21 +COc1ccccc1NC(=O)Cc1ccc(C)cc1 +N#Cc1ccc(CNCc2cn3cc(Cl)ccc3n2)cc1 +COc1cccc(-c2cc3nc(SC)n(N)c(=O)c3s2)c1 +Cc1nnc(N2CC3COCC3(C(=O)NCc3ccccn3)C2)s1 +O=C(Cn1ccc2ccc(Cl)cc21)Nc1nnc(C2CC2)s1 +Cc1ccc(Nc2nnc(SCCCO)s2)cc1 +CC(Sc1ccccn1)C(=O)N1CCCCC1CNC(N)=O +COc1ccc(CN2C(=O)CNC(=O)c3ccccc32)cc1OC +CC1CN(C(=O)c2ccc(-c3nnc(-c4ccccc4)o3)cc2)CCO1 +CNC(=O)NCC(=O)N(C)Cc1cccc(OC(F)(F)F)c1 +Cc1[nH]c2ccccc2c1-c1n[nH]c2ccc(N)cc12 +CC(C)(C)OC(=O)N1CCN(c2ccc(C#N)cc2)CC1 +Cc1c(C(=O)NCCCN2CC(C)OC(C)C2)[nH]c2c1C(=O)CCC2 +O=C(Cc1n[nH]c(=O)c2ccccc12)Nc1cccnc1 +Cc1cc(C)n2nc(NCc3ccccc3)nc2n1 +CC(C)CNC(=O)c1cccc(CN2CCn3c(nn(C)c3=O)C2)c1 +C=CCn1c(C(=O)NCCc2ccccn2)cc2sc(C)cc21 +C#CCN1CCN(CC(=O)NC(c2ccccc2)C(C)C)CC1 +O=C(c1cc2ccccc2c(=O)[nH]1)N(CC1CCCO1)c1ccncc1 +CCC(=O)c1ccc(Cl)c(S(=O)(=O)NC)c1 +CC(Cc1ccc(Cl)cc1)N(C)C(=O)c1ccc2[nH]nnc2c1 +COc1cccc(NC(=O)NCC(O)CC(C)C)c1 +CC(=O)Nc1nc(C(=O)OCCCc2cccc(C)n2)cs1 +O=C(Cc1cccnc1)N1CCCC(Cc2nc3ccccc3[nH]2)C1 +Cc1ccc(NC(=O)c2cccc3c2OCC(=O)N3)c2[nH]ncc12 +N#CCCCSc1nnc(-c2ccccc2Cl)n1N +CC(CNC(=O)c1cc(C2CC2)n[nH]1)c1ccccc1 +CC1(C)Cc2c(C#N)c(NCCO)nc(-c3ccco3)c2CO1 +O=C(C1CCCC1)N1CC2CCN(c3cnccn3)CC2C1 +O=c1[nH]c2ccccc2cc1CNc1cccc(CN2CCOCC2)c1 +Cc1ccccc1N1CCN(C(=O)C2CCCC2)CC1 +Cc1ncc(CNc2ccc3c(c2)CCC(=O)N3)s1 +O=C(CCn1ncc(=O)c2ccccc21)N1CCOC2CCCCC21 +CC(NC(=O)NCCCc1n[nH]c(N)c1C#N)c1cccs1 +Fc1ccc(C2(c3noc(-c4ccsc4)n3)CCOC2)cc1 +CCNC(=O)C1(c2ccc(Cl)cc2Cl)CCOCC1 +CCOC(=O)c1ccn(-c2ccc(NC(=O)c3cc(C)no3)cc2)n1 +Cc1nc(SCC(=O)O)[nH]c(=O)c1Cc1ccccc1 +Cc1cc(NC(=O)COC(=O)CCc2cccs2)no1 +Nc1c(-c2ccccc2)nsc1C(=O)NCC1CC1 +COCCCNC(=O)C1CCC(=O)N1Cc1ccc(F)cc1 +CCNC(=O)CC1C(=O)NCCN1Cc1cccc(C(F)(F)F)c1 +O=C(COn1nnc2ccccc21)Nc1ccc(Cl)c(Cl)c1 +COCCCNC(=O)c1cnc(SC)n1-c1ccc(F)cc1 +CCNC(=O)c1ccc(C)c(NC(=O)N2CCOCC2CC(C)C)c1 +O=C(Oc1ccccc1F)C1COc2ccccc2O1 +Cn1c(C(C)(C)C)nc2cc(NC(=O)c3cn4cccnc4n3)ccc21 +Cc1ccc(CNC(=O)c2ccc3c(c2)CCC(=O)N3)cc1 +CCc1ccc(NC(=O)NCCNC(=O)c2ccccc2)cc1 +Cc1cc(C)cc(NC(=O)c2nnc3n(C)ccn23)c1 +CN(Cc1ccc(S(C)=O)cc1)C(=O)c1scnc1C1CC1 +CCOCCN(C)S(=O)(=O)c1ccc(OC)cc1 +CCOc1c(N)cc(CN2CCOCC2)cc1OC +O=C(NCc1ccc2c(c1)OCO2)C1Cc2ccccc2S1 +CCOC(=O)CN(CC)C(=O)c1c(F)cccc1Cl +Cn1ccnc1COc1ccc(NC(=O)C2CC3CCC2O3)cc1 +COc1ccc(O)c(C(=O)NCc2nc(C)cs2)c1 +CC1CCCC(C)N1C(=O)CSc1nnnn1-c1cccc(F)c1 +O=C(c1ccco1)N1CCCC1c1ccc2c(c1)OCCCO2 +CCNc1c(F)cccc1C(=O)N(C)CC(C)C +COC(=O)c1c(C)[nH]c(-c2ccc3c(c2)OCO3)c1O +Cc1nc(C2(NC(=O)Cc3ccc(F)cc3)CCCC2)no1 +COc1ccc(-c2n[nH]c(NC(=O)CC3(O)CCCCC3)n2)cc1 +Cc1nn(C)c(=O)c(C(=O)NCC(C)(C)c2cccc(Cl)c2)c1C +O=C(Cc1ccc2ccccc2c1)Nc1ccccc1N1CCCC1=O +O=C(Nc1cccc(N2CCNC2=O)c1)c1ccc(Cl)cc1 +CCn1ccc2ccc(NC(=O)NCc3nncn3C3CC3)cc21 +CCOc1ccccc1CNC(=O)c1cc(S(N)(=O)=O)c(C)o1 +CNC(=O)c1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1C +O=C(Cn1nnc2ccccc2c1=O)Oc1ccc2c(c1)CCC2 +OCCCc1cnc2c(c1)c(-c1ccccc1)nn2CCO +Brc1cc(Br)c2c(c1)CCN2 +COc1ccccc1CNc1c2c(nc3nc(C)nn13)CCC2 +O=C(COCCc1ccccc1)Nc1ccc2c(c1)NC(=O)CS2 +CC(C1CC1)n1nccc1NC(=O)CSc1cc(F)ccc1F +Cn1cc(Br)cc(NC(=O)c2cccc(F)c2F)c1=O +CCc1nc(Cn2nnc3c(cnn3-c3ccccc3)c2=O)cs1 +CSc1ccc(C)c(C(=O)N2CCN(c3ccc(O)cc3)CC2)c1 +CC(C)NC(=O)NCC1COCc2nc3cccnc3n21 +CCOc1ccccc1CNC(=O)Nc1cc(F)ccc1OC +Cc1ccc(NC(=O)CSc2n[nH]c(=O)n2CC2CCCO2)cc1 +CSc1cnc(S(N)(=O)=O)cc1OC1CC1 +CC1Cc2ccccc2N1c1ncnc2c1cnn2C +CC(=O)NC(C(=O)N1CCCC(n2cccn2)C1)C1CCCC1 +O=C(Nc1ccc2nccn2c1)C1CCCCN1C(=O)c1ccco1 +Cc1cc(C(=O)N2CCCC2)ccc1NCc1ccc(F)cc1F +CCCn1cc(CN2CCCC3(C2)OCCO3)cn1 +O=C(Nc1ccc(Cl)cc1)NC1CCCC1O +Cc1ccccc1-c1nnn(CC(=O)NC(C)c2ccccc2)n1 +Cc1nc(CC(=O)N(C)Cc2nccn2Cc2ccccc2)cs1 +Cc1ccc2c(c1)N(CC(=O)N(C)Cc1ncc[nH]1)C(=O)CO2 +CC(CO)C(C)NC(=O)Nc1cccc(N2CCCC2=O)c1 +N#CC(NS(=O)(=O)CCc1ccccc1)c1ccccn1 +Cc1cc2nc(C(=O)Nc3cccc(F)c3)cc(C)n2n1 +CCN(CC(=O)Nc1ccc(N)cc1Cl)c1ccccc1 +CN(C)C(=O)c1ccc(C(=O)Nc2nc3ccccc3s2)cc1 +COc1ccccc1C(=O)COC(=O)Cc1c[nH]c2ccccc12 +CCn1cc(NC(=O)NCc2ccnc3ccccc23)cn1 +CC(CO)NC(=O)Nc1ccccc1-c1ccccc1 +COC(=O)CC(NC(=O)c1cc(C)n[nH]1)c1ccc(SC)cc1 +CCCNC(=O)C1(NCc2cnn(-c3ccccc3)c2)CCCCC1 +Cc1c(C(=O)N(C)Cc2ccc(C#N)cc2)cnn1-c1ccncc1 +CN(C)C(=O)C1CN(CCc2ccccc2)CCN1C +Cc1ccc2ncc(C(=O)N3CCN(C(=O)N(C)C)CC3)n2c1 +CCc1c(C)sc2nc(CC(=O)N3CCCC3)[nH]c(=O)c12 +COc1ccc(C(=O)NCc2ncc(-c3ccccc3)o2)c(O)c1 +Cc1cnccc1-n1nc(C2CC2)nc1CN1CCOC1=O +COc1ccc(OC)c(NC(=O)CSc2ncc3ccccn23)c1 +CCOC(=O)C(NC)c1c(F)c(F)c(F)c(F)c1F +CC(=O)Nc1cccc(NC(=O)c2ccc(-c3ccc(F)cc3)o2)c1 +CCC1Oc2ccc(S(=O)(=O)NC)cc2N(C)C1=O +CN(c1nccn2cnnc12)C1CCN(c2ccccc2Cl)C1=O +O=C(NCc1ccco1)c1cc(Sc2ncccn2)ccn1 +Cn1cc(C(=O)Cn2c(-c3ccccc3)noc2=O)cn1 +CC(C)(C)OC(=O)NCCC(=O)Nc1ccc(CC#N)cc1 +Cc1ccccc1NS(=O)(=O)c1ccc(C(=O)N(C)C)cc1 +O=c1[nH]ncc(NCc2cccc(CN3CCOCC3)c2)c1Cl +COc1ccc(-n2ccc(CNC(=O)NCC(F)(F)F)n2)cc1 +Cc1ccc(N2CCC(C(=O)Nc3ccn(C)n3)C2=O)cc1 +CCOCCC1CCN(C(=O)c2ccncc2CC)CC1 +COCc1nc2cc3c(cc2n1Cc1cccc(C#N)c1)OCCO3 +Cc1cccc(C(=O)N2CCC(CN3CCCCC3=O)CC2)n1 +Cc1onc(-c2ccccc2Cl)c1C(=O)N1CCc2nocc2C1 +Cc1ccccc1C(=O)Nn1cnc2c(cnn2-c2ccccc2)c1=O +Cc1ccc2cccc(Nc3nc[nH]c(=O)c3N)c2n1 +CC1CC(N2CCN(C(=O)c3cc(Cl)ccc3F)CC2)C(=O)O1 +CC(c1ccco1)N(C)C(=O)Nc1ccccc1F +COc1ccnc(NC(=O)CCC2CCC(C)O2)c1 +O=C(CNC(=O)c1ccc2c(c1)CCC2)NCc1nc2ccccc2[nH]1 +CCOc1ccc(OCC(=O)NCc2nc3ccccc3[nH]2)cc1 +O=C(Nc1cncc(C#Cc2ccccc2)c1)N1CCCCC1 +CCC(=O)Nc1ccc(NC(=O)c2ccccc2OC)cc1 +O=C(NCc1c(F)cccc1Cl)c1ccn2nccc2c1 +Cc1n[nH]c2ncc(C(=O)NCCCN3CC(C)OC(C)C3)cc12 +CN(C(=O)c1ccc(Cn2ccccc2=O)o1)c1ccnn1C +CCC(NC(=O)CCc1c(C)nc(C)[nH]c1=O)c1ccc(C)cc1 +CCOC(=O)CN(C(=O)c1ccc(CC)o1)C(C)C +CCOC(=O)c1nc2ccccc2nc1NCc1ccccn1 +COCCNc1nnc(S(=O)(=O)Cc2ccccc2C)s1 +Cc1nc2ncc3c(=O)n(-c4ccccc4)ccc3n2n1 +N#Cc1cccc(CNc2cnn(-c3ccccc3Cl)c2)c1 +CC(NC(=O)Nc1ccc2c(c1)COC2)c1nc(C2CCCC2)no1 +COc1ccc(Cl)cc1NC(=O)COc1cccc2c1CCC2=O +Cc1ccc(Oc2cccc(C(=O)N3CCOCC3)c2)nn1 +CC(Oc1ccccc1)C(=O)N(C)Cc1nc(-c2ccccc2)no1 +CC(C)C(=O)N(C)Cc1nnc(-c2ccccc2)o1 +CC(C)(C)OC(=O)NCC(=O)Nc1ccc(Cl)cc1F +CC(C)n1cc(C(=O)N(C)Cc2cnn(-c3ccc(F)cc3)c2)cn1 +Nc1cccc(CS(=O)(=O)N2CCCCCC2)c1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccc3c(c2)CCC3)cc1 +Cc1cc(-n2nnc(C(=O)N3CCCC3)c2C)ccc1Br +O=C(CSc1ccccc1O)Nc1cc(F)ccc1F +Cc1cccnc1NC(=O)C1COc2ccccc2C1 +CCn1nnc2cc(-c3noc(CNC(=O)c4ccco4)n3)ccc21 +Nc1cccc2c1N(CC(=O)c1cccs1)CCO2 +CN(C)C(=O)C1CCCN(C(=O)C2(c3ccc(F)cc3)CCCC2)C1 +O=C(NCC1CCOC1)Nc1cccc2c1CCCC2 +N#Cc1ccc(N2CCC(C(=O)N3CCc4ccccc4C3)CC2)nc1 +Cc1noc(C)c1S(=O)(=O)NCc1cccc(C#N)c1 +O=C(NCc1ccnc(OCc2ccccc2)c1)c1ccc(F)cc1 +Cc1ccc(S(=O)(=O)N(C)Cc2c(C)nn(C)c2C)cc1 +CC(C)COCCC(=O)Nc1ccc(F)c(N)c1 +Clc1ccc2nc(-c3ccccc3)c(CN3CCOCC3)n2c1 +CC(C)CCC(C)NC(=O)c1ccc2c(c1)OCO2 +CN(Cc1cccc2ccccc12)C(=O)CCNC(=O)OC(C)(C)C +CN(Cc1cscn1)S(=O)(=O)c1ccnc(N)c1 +CCN(CC)C(=O)c1cc2cc(Cl)ccc2oc1=O +Fc1cnc(N2CCC3(CC(Oc4cccnc4)CO3)C2)nc1 +Cc1nc2nc(C(F)(F)F)nn2c(C)c1CC(=O)NC(C)C(C)C +CN(C(=O)COc1ccc(N(C)S(C)(=O)=O)cc1)C1CC1 +COC(=O)c1ccc(NC(=O)CSc2nc(C)c(C)c(C)n2)cc1 +CC1CN(C(=O)NCc2cccc(C#N)c2)c2ccccc21 +O=C(Nc1ccccc1)C1CCCN(C(=O)c2ccoc2)C1 +CNCC(=O)OCc1cc(Br)ccc1F +CCn1cc(NC(=O)Cn2cc(Cl)c(C)n2)c(C(=O)OC)n1 +CCN(CCO)C(=O)c1ccc2c(c1)OCC(=O)N2 +O=C(Nc1ccc(SC(F)F)cc1)c1cc[nH]n1 +CNS(=O)(=O)c1cc(S(C)(=O)=O)ccc1C +CCOc1ccc(-c2nnc(NC(=O)c3ccnn3C(C)C)o2)cc1 +O=C1CN(Cc2nc(-c3ccc(-c4ccncn4)cc3)no2)CCN1 +CCn1c(C)cc(C(=O)NCc2cccnc2OC)c1C +Cc1cccc(CC2Oc3ccc(N)cc3NC2=O)c1 +CCC(=O)N1CCN(Cc2cnc(C(C)C)s2)CC1 +Cc1nc(C)c(C(=O)Nc2ccc3c(c2)CCC3)s1 +COc1ccccc1CNC(=O)c1cc(C)n(C)n1 +CCCOc1ccccc1NC(=O)NC(CC)CO +CC(C)c1nc(C#N)c(-c2ccc3c(c2)OCO3)[nH]1 +OC1C2(CCCO2)C(O)C2(CCCO2)C(O)C12CCCO2 +CN(C)c1cccc(C(=O)N(CCC#N)CCN2CCOCC2)c1 +CC(=O)Nc1ccc(NC(=O)c2cccc(C)n2)cc1C +CS(=O)(=O)NCc1ccc(NC(=O)CCc2cccs2)cc1 +CC1CCCCN1C(=O)C1CCCCN1C(=O)c1cccs1 +CC(CNC(=O)c1c[nH]c2cccc(F)c12)CC1(C)OCCO1 +CNC(=O)c1ccccc1NC(=O)CSc1nncn1C(C)C +CCCc1nnc(NC(=O)C(C)(C)NC(=O)OC(C)(C)C)s1 +CCn1cc(NC(=O)NCC(O)c2ccccc2OC)cn1 +O=C(NCCNS(=O)(=O)c1cccc(Cl)c1Cl)C1CC1 +Cc1nc(CC2CCN(C(=O)c3cc(=O)n(C)c(=O)n3C)CC2)no1 +CC1CCCCC1NS(=O)(=O)c1cn(C)nc1N +Cc1nn(C)c2[nH]nc(NC(=O)CCn3nc4ccccn4c3=O)c12 +Cc1nn(CC(=O)N2CCCCC2)c(=O)c2cc3sccc3n12 +CCCCNC(=O)C1CCCCN1C(=O)c1ccccc1 +CCCc1nnc(C(=O)N2Cc3cnn(CCO)c3C2)o1 +CCOCCNC(=O)Nc1c(C)nn(CC)c1C +CC(C)OCCn1c(=O)c2ccc(C(F)(F)F)nc2n(C)c1=O +Cc1nc2nc(N)nn2c(C)c1CCC(=O)NC1CCCCCC1 +Cc1ccc(NC(=O)c2cc(Br)cn2C)cc1F +CS(=O)(=O)N1CCc2ccc(NC(=O)NCc3ccccc3)cc21 +Cc1cc(C(=O)CSc2nnc(C3CC3)n2C2CC2)c(C)[nH]1 +Cc1cc(C(F)(F)F)nn1CC(=O)NCC1CCCO1 +CCOC(C)C(=O)Nc1c[nH]cc(Br)c1=O +C#CCCCCNC(=O)Nc1ccc(C(C)=O)c(C)c1 +CCCNC(=O)C1c2ccccc2CC(=O)N1C(C)C +O=C(Nc1nc(C(F)(F)F)cs1)c1cc2ccccc2oc1=O +COCC(=O)NC1(C(=O)NCC2CC2)CCCC1 +CNC(=O)c1cccc(NCc2ccccc2OC(F)F)c1 +Cn1c(-c2ccccc2Cl)nc2cc(C(=O)N3CCCC3)cnc21 +CC(c1ccccc1)N(C)C(=O)CSc1nnc(N)n1C +O=C(c1ccc2[nH]cnc2c1)N1CCN(CC(F)(F)C(F)F)CC1 +N#Cc1ccc(OCCn2nc(-c3ccccc3F)ccc2=O)cc1 +COc1cc(S(=O)(=O)NCC(C)C)ccc1NC(C)=O +CCN1CCN(C(=O)COc2ccc(Cl)cc2Cl)CC1 +CCCC(=O)N1CCN(Cc2noc(-c3cccc(F)c3)n2)CC1 +CC(Sc1nnc(-c2ccc(F)cc2)n1-c1ccccc1)C(N)=O +CSc1ccccc1NC(=O)c1cc(Br)c[nH]1 +CC1CC(C)CN(C(=O)Cn2c(=O)cnc3ccccc32)C1 +COc1ccc(Cl)cc1NS(=O)(=O)c1c(C)noc1C +NC(=O)CSc1ccccc1NC(=O)COc1ccccc1F +CCNC(=O)CS(=O)(=O)c1cc(C(C)(C)C)ccc1C +COc1cccc(NC(=O)Cc2noc3ccccc23)c1 +Cc1cnc2n(c1=O)CC(C(=O)N(CCO)C(C)C)CS2 +CC(C)CNC(=O)CN1C(=O)Cc2cc(N)ccc21 +CCOC(=O)C(C)N1CCN(C(C)C(=O)N2CCCC2)CC1 +Nc1ncc2c(n1)CN(CCc1cccs1)C2=O +Fc1cc(Br)ccc1NCc1nccn1C(F)F +Cn1cc(CNc2ccc(-n3cccn3)cc2)c(-c2cccnc2)n1 +COC(=O)Cn1cc(NS(=O)(=O)c2ccccc2Cl)cn1 +Cc1ccc(-n2ncc3c(NCc4cccnc4)ncnc32)c(C)c1 +COc1ccc(-c2nnc(C(C)Sc3nccn3C3CC3)o2)cc1 +Nc1cccc(OCCCSc2ccccn2)c1 +CN(Cc1ccccc1)C(=O)c1ccccc1Br +CC(=O)c1cc2c(cc1NC(=O)c1cc(C)no1)OCO2 +Cc1ccc(N2CCC(C(=O)NCCNC(=O)C(C)C)C2=O)cc1 +NC(=O)c1csc(CN2CCc3cc(F)ccc3C2)c1 +CNS(=O)(=O)c1ccc2c(c1)N(c1ncnc3sccc13)CC2 +CCOc1c(Cl)cc(C(=O)Nc2ncc(C)s2)cc1OC +COc1cccc(NC(=O)COC(=O)c2ccc3c(c2)OCCO3)c1 +COC(=O)CCSc1ncc(-c2ccc(F)cc2)o1 +O=C(Cc1cccs1)Nc1cnn(CC(=O)NC2CCCC2)c1 +O=C(CCn1ccnc1)N1CCN(c2ccccc2)CC1 +N#Cc1cccc(NC(=O)N2CCCC2C(=O)NC2CC2)c1 +Cc1nc(-c2ccc(NC(=O)C3(c4ccccc4)CC3)cc2)cs1 +CCCNC(=O)CN(C)C(=O)CNc1ccc(F)cc1Cl +CN1CCN(C(=O)CSc2nc3c(cc2C#N)CCC3)CC1 +CCC(CNC(=O)c1n[nH]c(=O)[nH]1)Oc1cccc(F)c1 +COc1ccc2nc(NC(=O)c3cc(C(N)=O)cs3)sc2c1 +CCCn1c(N)c(C(=O)CN2CCc3ccccc32)c(=O)[nH]c1=O +Cc1ccc(S(=O)(=O)N2CCCC(c3nc(C)no3)C2)c(C)c1 +CN(C)S(=O)(=O)N1CCC(OCc2ccc(F)cc2)CC1 +CN(Cc1cnccn1)C(=O)C1(Cc2ccccc2)CCC1 +CCCc1nnc(NC(=O)c2cnc(C3CC3)nc2N)s1 +CC1CCCN(c2nc(-c3ccc(NC(N)=O)cc3)cs2)C1 +CCCc1cc(C(=O)N2CCC(N(C)c3ccccc3)CC2)[nH]n1 +O=C(CCSc1ccccn1)Nc1cc(-n2cccc2)ccc1F +Cc1cc(C)cc(C(=O)N(C)CCC(F)(F)F)c1 +COc1ccc(CN2CCN(C(=O)Nc3ccn(C)n3)CC2)cc1F +CCc1cnc(CN(C)C(=O)NC(C)c2csc(C)n2)s1 +Cn1ncc(-c2ccc(Cl)cc2)c(CO)c1=O +N#Cc1ccc(S(=O)(=O)N2CCCC(C(F)(F)F)C2)cc1 +CN(C)c1ccc(C(=O)Nc2nnc(-c3cccc(F)c3)o2)cc1 +O=C(Cc1cccc2cccnc12)N1CCc2ccccc21 +Cc1cc2[nH]c(=O)[nH]c2cc1S(=O)(=O)NCCC(C)C +COc1ccccc1CNC(=O)c1ccc(-n2ccnn2)cc1 +COc1ccc2c(c1)CN(C(=O)c1csnn1)CC2 +Cc1nc2ccccc2n1CC(=O)OCC(=O)c1ccc2c(c1)CCC2 +CN(C)c1cccc(C(=O)Nc2ccccc2N2CCOCC2)c1 +Cc1ccc2ncc(C(=O)N(Cc3ccco3)C3CCCC3)n2c1 +CCCCCn1c(=O)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O +Cc1nccc(NCc2cccc(S(=O)(=O)N3CCCCC3)c2)n1 +CN(C)C(=O)N1CCCC(C(=O)NC2CCCCC2)C1 +CCn1ncc(NC(=O)Cc2cccs2)c(N2CCCCC2)c1=O +CCn1nc(CO)cc1-c1ccc(OC)cc1OC +NC(=O)C1CCN(C(=O)Cc2ccc(OC(F)F)cc2)CC1 +CCc1nnc(NC(=O)c2cc3ccccc3oc2=O)s1 +Cc1ccc(OC(C)C(=O)N2CCOCC2)cc1C +CS(=O)(=O)N1CCc2nc(NC(=O)Cn3cccn3)sc2C1 +Cc1cccc(C(C(=O)NC2(CO)CCCCCC2)N(C)C)c1 +COc1ccc(CC(C)OC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +Cc1c(Cl)cccc1OCC(=O)Nc1nccn(C)c1=O +CCc1noc(CC)c1CNC(=O)C(C)Cc1c(C)noc1C +Nc1nc(-c2cccs2)ccc1C(=O)N1CCCCCC1 +CC(=O)C1CCC2C3CCC(=O)C(C)C3CCC12C +Cc1ccc(SC(C)C(=O)Nn2cnc3ccccc32)cc1 +CCOC(=O)CN(C(=O)c1ncccc1O)C1CC1 +Cc1cc(F)cc(C(=O)OCC2CC(=O)N(C3CC3)C2)c1 +CC(=O)Oc1ccc(C(=O)Nc2ncccc2C)cc1 +CC(C)COc1ccc(CCNC(=O)c2ccc(F)nc2)cc1 +CN(C)c1cccc(NC(=O)NCCSc2ncn[nH]2)c1 +CC(C)c1noc(CCNC(=O)CN(C)c2ccccc2)n1 +O=C(c1cc(S(=O)(=O)N2CCCCC2)c[nH]1)N1CCCCC1 +CC(NC(=O)c1ccc(C(=O)N(C)C)cc1)c1cccc2ccccc12 +Cc1ccc(C(=O)OC(C)c2nc3ccccc3n2C)cn1 +Cc1ccccc1C(CC(=O)OCC1CCCCO1)NC(N)=O +c1ccc(-n2ncc3c(NCc4cccs4)ncnc32)cc1 +COc1c(O)ccc2c1C(C(O)c1ccccc1)NCC2 +COC(C)c1cccc(NC(=O)C2CC(=O)N(CC(F)(F)F)C2)c1 +COc1ccc(C(C#N)CCC(=O)NC(C)C)cc1C +CN(Cc1cnn(C)c1)C(=O)NCCc1cc(Cl)cc(Cl)c1 +Cn1nc(-c2cccs2)cc1C(=O)NCc1cccnc1 +Cc1ccc(-c2nnc3sc(-c4cc(C)on4)nn3c2=O)cc1 +CN(Cc1ccccc1)Cc1nc2cc(Cl)ccc2[nH]1 +Cc1cccc(C2(Cc3c(F)cccc3Cl)NC(N)=NC2=O)c1 +O=c1n(CCCNc2nccc(C(F)(F)F)n2)nc2n1CCCC2 +O=C(CCCC1CCCC1)N1CCOCC1C1CC1 +COc1cccc(NC(=O)COc2cc(C)ccc2C(C)=O)c1 +O=C(COc1ccc(Cl)c(Cl)c1)NCc1cc[nH]n1 +CCCc1nnc(NC(=O)c2sc3nc(C)nc(C)c3c2C)s1 +Cc1cc(C)n(C2CN(Cc3csc(-c4ncccn4)n3)C2)n1 +COc1ccc(CC(=O)Nc2cc(S(C)(=O)=O)ccc2F)cc1 +NC(=O)c1cccc(CNC(=O)c2ccc(-n3ccnn3)cc2)c1 +CCS(=O)(=O)NCCNS(=O)(=O)c1cc(F)c(F)cc1F +CCCC(CC(=O)OC)c1cc(C)c(OC)cc1C +CC1CN(C(=O)C2CC(=O)N(Cc3ccccn3)C2)CC(C)O1 +COC(=O)C(C)CN(C)C(=O)C(N)c1ccccc1 +COC(=O)c1cc(CNC(=O)N2CCC3(CC2)OCCO3)oc1C +Cc1ccc2c(c1)CCCN2C(=O)c1ccc(-n2ccnn2)cc1 +CCOCC1CCCN(C(=O)Nc2cc(OC)cc(OC)c2)C1 +Cc1ccccc1S(=O)(=O)NC(=O)c1ccccc1 +CC(=O)N1CCC(C(=O)Nc2cnc3ccccc3c2)CC1 +CC(C)n1cc(C(=O)NCc2c(F)cccc2F)c2n[nH]c(=O)c-2c1 +CC(C)C(=O)NCC1CCCN(C(=O)Cc2ccccc2Cl)C1 +CCn1c(CN2CCCC2Cn2cccn2)nc2cc(F)ccc21 +Clc1ccc2scnc2c1NCc1cnccn1 +CN(C)C(=O)c1ccc(NC(=O)CCc2c[nH]c3ccccc23)cc1 +CC(=O)Nc1nc(C(=O)Nc2ccc3c(c2)OC(F)(F)O3)cs1 +CN1C(=O)CC(C(=O)NCC(=O)N2CCCC2)C1c1cccnc1 +COCCN(CC(=O)N(C)C)C(=O)c1ccc(-n2cccn2)cc1 +Cc1cc(C)cc(OCCc2nc(C)c(C#N)s2)c1 +CCOCC(=O)OCC1COc2ccccc2O1 +O=C(c1cccnc1)N1CCC(C(=O)N2CCOCC2)CC1 +O=C1COc2cccc(OCc3cccc(F)c3Cl)c2N1 +CC(C)C(=O)Nc1ccc(C(=O)N(Cc2cccnc2)C(C)C)cc1 +CCCc1cc(N2CCN(C(=O)c3ccco3)CC2)nc2nncn12 +CCN(CC(C)C#N)C(=O)CSc1nc2ccccc2nc1C +CC1(C)CC(=O)c2cnc3c(c2C1)c(=O)[nH]c(=O)n3Cc1ccccc1 +CCc1ocnc1-c1nc(CC(C)C)nn1-c1ccccn1 +O=C(NCc1cccc(CN2CCOCC2)c1)N1CCCC(O)C1 +CC(OC(=O)c1cccnc1)C(=O)NCC(F)(F)F +CCC(C)C(NC(=O)CCn1c(C)csc1=O)C(N)=O +CC(C(N)=O)n1cc(-c2cnc3ccccc3c2)cn1 +N#Cc1ccc(S(=O)(=O)NCCC(=O)NCc2ccccc2)cc1 +CSc1ccc(NCc2ccccc2C(N)=O)cc1 +CC(C)CC(C(=O)NC1CCC(=O)NC1)N1CCCCC1=O +CCN1C(=O)CCc2cc(NC(=O)c3ccc(F)c(F)c3)ccc21 +CCc1onc(C)c1NC(=O)C1(CC(C)C)CCC1 +CCCN(C(C)C)S(=O)(=O)c1cc(N)ccc1OC +Cc1ccc(C(C)NC(=O)N(CCO)C2CC2)o1 +O=C(NC(CC(=O)N1CCC1)c1ccccc1)c1ccccc1Cl +CC(CNC(=O)COc1ccccc1F)N1CCc2ccccc21 +Cc1ccc(CNC(=O)C2CCC(=O)N(C)C2c2ccccc2)o1 +Cc1ccc(C)c(NC(=O)Cn2c(=O)n(C)c(=O)c3nscc32)c1 +CCC(NC(=O)c1cc(OC)c(OC)cc1C)c1c(C)nn(C)c1C +COCn1c(=O)c(-c2ccccc2)nc2ccc(N)cc21 +CN(C(=O)Cc1nc2cc(N)ccc2o1)C1CCCCC1 +CCc1cnc(C(C)NC(C)c2ccc(S(N)(=O)=O)cc2)s1 +Cc1noc(C)c1C(=O)NC(C#N)c1ccccc1 +CCC1CN(C(=O)CCC(=O)c2cc(C)sc2C)CC1O +C=CCNc1cc(S(=O)(=O)N(C)C)ccc1OCC +CCCNC(=O)CCNC(=O)Nc1c(F)cccc1F +Cc1cc(C)n(C(=O)CCOc2ccc3ncccc3c2)n1 +CS(=O)(=O)Oc1ccc(Br)cc1 +Clc1ccc(-c2ccc(Br)cn2)nc1 +OC(CN1CCCc2ccccc21)c1cccnc1 +CCOC(=O)N1CCN(C(C)Cc2ccc(OC)c(N)c2)CC1 +NC(=O)c1ccc(C(=O)NCCCn2cnc3ccccc32)cc1 +Cc1nc2cc(OCC(F)(F)F)c(N)cc2s1 +N#Cc1ccsc1NCc1c(F)cccc1Cl +CNC(=O)CC1CCN(C(=O)c2cccc(-c3ccoc3)c2)CC1 +O=C(CC(c1ccccc1)c1ccccc1F)NCCc1cn[nH]c1 +COc1ccc(CNC(=O)c2oc3c(c2C)C(=O)CCC3)cc1OC +COc1ccc(-c2ccc(C#N)c(=O)n2CCCO)cc1OC +CCS(=O)(=O)Nc1cc(C(F)(F)F)ccc1F +COC(=O)c1sc(COc2ccccc2F)nc1C +Cn1ncnc1CCNC(=O)NCc1cccc(OC2CCCC2)c1 +O=C(Nc1cccc(F)c1F)c1ccncc1F +COc1cc2c(Cc3ccc(OC)c(OC)c3)nccc2cc1O +O=C1COc2ccc(-c3cscn3)cc2N1CCN1CCOCC1 +O=C(NCCc1ccc2c(c1)OCCO2)c1cc2c(s1)CCC2 +Cc1cc(C)cc(OCCN(C)C(=O)CCC(=O)N2CCOCC2)c1 +N#Cc1ccc(C(=O)Nc2ccsc2-c2nnc(C3CC3)o2)cc1 +C#Cc1cccc(NCc2cc(Br)c(O)c(OC)c2)c1 +Cc1cc(CNC(=O)C2(c3ccc(F)cc3)CCC2)c(C)o1 +C#CCN1CCN(C(C)C(=O)NC(C)c2ccccc2OC)CC1 +CCSc1ncc(-c2nccn2Cc2noc(C(N)=O)n2)cn1 +COc1ccccc1Oc1ncnc(N(C)c2ccccc2)c1N +Cc1cc(F)ccc1CCNC(=O)Nc1ccncc1 +COC(=O)C1CCC(=O)N1c1cccc(Cl)c1Cl +CCOC(=O)C=C(N1CCC(C(N)=O)CC1)C(F)(F)F +CC(=O)Nc1ccc(OCC(=O)NCCc2cccs2)cc1 +CCN(CC)C(=O)c1cc2c(cc1Br)OCCO2 +CCNC(=O)NC1CCC(OC(=O)c2cc(CC)c(C)s2)CC1 +Cn1cccc1C(=O)NC1CC1c1cccc(Cl)c1 +CC1CN(C(C)C(=O)N(C)C2CCCCC2)CC(C)O1 +N#Cc1cccnc1NCc1ccc(S(=O)(=O)NC2CC2)cc1 +Cc1ccc(C(=O)N2CCN(C(=O)NC3CCCC(C)C3)CC2)s1 +COc1ccc(Cl)cc1NC(=O)C(C)Cn1nc(C)cc1C +NC(=O)C(c1ccccc1)c1cncc(N2CCOCC2)n1 +Cc1[nH]c2ccccc2c1C(=O)NCc1ccncc1 +O=C(Cc1c(F)cccc1F)Nc1cc(-c2cccs2)n[nH]1 +CCOC(=O)C(C)Sc1nc(=O)n2ccc(C)cc2n1 +CNC(=O)Cc1cc(=O)[nH]c(SCC=Cc2ccccc2)n1 +CCc1nc(CNC(=O)NCc2ccccc2CC)cs1 +CC(C)CNC(=O)N1CCN(CC(=O)NC2CC2)CC1 +Clc1ccc(CNc2ncnc3[nH]cnc23)cc1 +Cc1csc(NC(=O)Cc2ccc(F)c(Br)c2)n1 +Cc1cc(C)n(Cc2nc(N)nc(N3CCOCC3)n2)n1 +OCCn1nnc(CO)c1C(Cl)(Cl)Cl +COC(=O)CSc1nc2nccc(-c3ccccc3OC)n2n1 +N#Cc1ccccc1OCC(=O)N1CCc2ccccc21 +CNC(=O)C1CCCN(c2cnn(Cc3ccccc3)c(=O)c2)C1 +COc1ccc(-c2[nH]c3c(=O)n(C)c(=O)n(C)c3c2O)cc1 +C=CCNC(=O)CCn1cnc2c(-c3ccccc3)noc2c1=O +Cc1noc(NC(=O)CCn2c(C)csc2=O)n1 +CCN(CC1CC1)C(=O)Nc1cc(F)c(OC)cc1OC +CS(=O)(=O)NCCNC(=O)c1ccc(-n2ccnc2)cc1 +Cc1cc(C(=O)NC2(C)Cc3ccccc3C2)c(C)n1C1CC1 +OCCn1ncc2c(NCc3ccc4c(c3)OCO4)ncnc21 +CC(C)CCC(C)NC(=O)Cc1csc(-c2cccnc2)n1 +COc1ccc(C2CN(C(=O)C(C)C)CC2C(=O)NCC(C)C)cc1 +OC1=Nc2c(cnn2C2CCCC2)C(c2ccc(F)c(F)c2)C1 +CCN(C)C(=O)CS(=O)(=O)N1CCN(c2cccc(C)c2)CC1 +CCSc1cncc(N2CC(C)OC(C)C2)n1 +Cc1nc2ccc(C(=O)OCC(=O)OC(C)(C)C)cc2nc1C +CN(C)C(=O)Cc1ccc(NCc2ccc(Br)cc2)cc1 +COc1ccc(C(=O)N2CCC(OC)C(Cc3ccccc3)C2)cc1 +N#Cc1ccccc1NC(=O)c1cc(=O)[nH]c2ccccc12 +Cc1ccc(NC(=O)c2cccc3ccnn23)cc1 +O=C(Cc1ccc(F)cc1F)Nc1cnn(Cc2ccccc2)c1 +COc1cc(NC(=O)NCC2(O)CCc3ccccc32)cc(OC)c1 +COc1ccc(Cc2nc(C)c(CC#N)s2)cc1OC +CCn1c(=O)[nH]c2c(C(N)=O)nc(-c3cccs3)nc21 +CCN1CCc2c(cc(C#N)c(=O)n2C2CCCC2)C1 +Nc1ccccc1OCCNC(=O)Cc1ccc(F)cc1 +COc1ccccc1-c1nnc(SCCc2scnc2C)n1N +CCOCCOC(C)C(=O)Nc1ccccc1C#N +CC(CNC(=O)CC(F)(F)F)c1nc(-c2ccccc2)no1 +COCCOC(=O)C(C)n1c(C)ccc(C(C)=O)c1=O +COCCN1CC(C(=O)NCc2ccccc2C)CC1=O +CCCOc1ccc(N(CC)S(C)(=O)=O)cc1 +O=C(COc1cc(Cl)ccc1Cl)N1CCn2c(n[nH]c2=O)C1 +CCc1onc(C)c1NC(=O)CC=Cc1ccc(F)cc1 +O=C(NCCC1=CCOCC1)NCc1ccn(-c2ccc(F)cc2)n1 +c1ccc(C2(c3nc(-c4cnccn4)no3)CCC2)cc1 +CCNC(=O)c1ccc(N2CCN(C(=O)N3CCOCC3)CC2)nc1 +CCN1C(=O)Cc2cc(C(=O)NCc3ccc(C)cc3)ccc21 +CC(C)C(=O)NCCNC(=O)c1ccc(Cl)c(Cl)c1 +Cc1ccc(-c2noc(-c3cccn3CC(=O)NC(C)C)n2)cc1 +COc1ccc2c(c1)S(=O)Cc1ccccc1C2=O +CC(Sc1nnnn1C1CCCC1)C(=O)Nc1ncccn1 +COc1cc2c(cc1OC)C(C)N(C(=O)N1CCOCC1)CC2 +Nc1ccc2oc(-c3cccc(-c4nc5cc(N)ccc5o4)c3)nc2c1 +Cc1ccc2cnn(CCC(=O)NCCc3ccco3)c2c1 +CCOc1ccc(NC(=O)NCc2ccc(C(=O)NC)cc2)cc1F +CCCCC(COC)NC(=O)N1CCN(C(=O)C(C)(C)C)CC1 +COc1ccc(OC)c(CNC(=O)N2CCc3ccccc32)c1 +Cc1ccc(C)c(SCC(=O)Nc2ncc(C(N)=O)s2)c1 +CCOC(=O)Nc1sc2c(c1C(N)=O)CCCC2 +COc1ccc(N)cc1CNC(=O)c1ccc(C)nc1 +CCC(Oc1ccc(C)c(C)c1)C(=O)Nc1ccon1 +COCCNS(=O)(=O)c1cc(-c2ccc(=O)[nH]n2)cs1 +Cc1csc(NC(=O)NC(c2ccc3c(c2)OCCO3)C(C)C)n1 +Cc1ccncc1NC(=O)NCCc1cnn(C)c1 +O=C(Cn1nc2c(cc1=O)CCCC2)NC1CCCCCC1 +CSc1nc2ncn(Cc3cccc(C#N)c3)c(=O)c2s1 +Cc1ccccc1C(=O)N1CCC2(CCC(=O)N(CCCO)C2)CC1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)N(C)CC3CC3)c12 +O=C(Cc1cccc(Cl)c1)N1CCN(Cc2ccno2)CC1 +COc1ccc(NC(=O)NCC2CCOC2)cc1C +NC(=O)C1CCCN(c2ncnc3sc(-c4ccccc4)cc23)C1 +Nc1c(Cc2ccc(Br)cc2)cc[nH]c1=O +CC(C)c1ccc(NC(=O)COc2ccc(N)cc2F)cc1 +CCC(=O)Nc1ccc(O)c(C(=O)NCc2ccccc2COC)c1 +Cc1cc(C)n(-c2cccc(NC(=O)C(C)NC(N)=O)c2)n1 +O=C(NC1COc2ccccc21)c1cnc(C2CCCO2)s1 +Cc1cc(C)n(CC2CN(CC(C#N)CCC#N)CCO2)n1 +Cc1nc(NCCNC(=O)C(C)(C)C)cc(-n2cccn2)n1 +Cc1cccc(NC(=O)Oc2cccc3cccnc23)c1 +c1ncc(N2CCOCC3(CCCN(Cc4nccs4)C3)C2)cn1 +FC(F)(F)c1nnc2sc(-c3cccnc3)nn12 +O=C(CC1(O)C(=O)Nc2cc(Cl)ccc21)c1ccco1 +COc1cc(C(C)=O)ccc1OCc1ccccn1 +CN(c1ccc(O)cc1)S(=O)(=O)c1cn[nH]c1 +CC(c1ccccc1)N(C)C(=O)CSc1n[nH]c(=O)n1C +O=C(CSc1nc2ccccc2[nH]1)Nc1ccccc1O +Cc1cc(NC(=O)Cc2ccc(Cl)c(Cl)c2)n(C)n1 +Cc1cccc(OCCN2CCN(S(=O)(=O)N(C)C)CC2)c1 +CC1CCCN(C(=O)NCCC(=O)NC2CCCCC2)C1 +CNC(=O)Cc1ccc(NC(=O)C(C)c2cccs2)cc1 +Cc1ccc(-c2cc(C(=O)NCCc3c[nH]c4ccccc34)[nH]n2)o1 +O=C(C1CCCC1)N1CCC(n2c(=O)oc3cccnc32)CC1 +Cc1nc(-c2cncc(Br)c2)cc(N2CCOCC2)n1 +N#CCCN(C1CC1)S(=O)(=O)c1ccccc1F +CCCCn1nc(C(=O)Nc2nnc(C)s2)c2ccccc2c1=O +CCn1c(=O)n(CC(=O)NC2CCCCC2)c(=O)c2ccccc21 +COc1ccc(C(=O)Nc2cnn(C3CCOCC3)c2)cc1 +CCc1n[nH]c(C2CN(C(=O)c3c[nH]c(C(C)C)n3)CCO2)n1 +COc1cc(N)ccc1NC(=O)c1cccc(C)c1C +CCOC(=O)CN(CC)C(=O)c1cc(N)cnc1C +COc1cc(C)sc1C(=O)N1CCN(C(=O)C(C)(C)C)CC1 +C#CCN1CCC(C(=O)N2CCOCC2C2CC2)CC1 +CC(C)(C(=O)NCCCNC(=O)c1cccs1)c1ccccc1 +Cc1ccc(C)c(OCn2ccc(C(=O)N(C)CC3CC3)n2)c1 +Cn1ccnc1SCCn1cnc2c1c(=O)n(C)c(=O)n2C +O=C(Nc1ccc(Cl)cn1)c1cccnc1N1CCCCC1 +CC(Oc1ccccc1Br)C(=O)Nc1cccc(O)c1 +CC1CN(C(=O)c2ccccc2S(C)(=O)=O)CC(C)O1 +CC(C)c1ccc(-n2ccc3c(nnc4ncnn43)c2=O)cc1 +CCCNC(=O)CNc1ccccc1-n1cccn1 +CC(C)CC(c1nc(Cc2cccnc2)no1)N1CCCCC1=O +O=C(NCc1ncccc1F)c1cccc(-c2ccoc2)c1 +CC(=O)N(C)CC(=O)OC(C)C(=O)Nc1ccc2ccccc2c1 +CC(C(=O)N1CCCCC1)S(=O)(=O)c1nc2ccccc2[nH]1 +O=C(CNC(=O)c1ccnc(OCc2ccccc2)c1)NC1CC1 +CCS(=O)(=O)NC(C)COc1cccc(F)c1 +COc1ccc(NC(=O)c2ccccc2CC#N)cc1Cl +CC(C)C(CO)NC(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +COCCNC(=O)C(C)Sc1nc(-c2cccs2)n[nH]1 +COC(=O)C(C)S(=O)(=O)N(CCO)C1CCCCC1 +Cc1cc(OCC(=O)N2CCc3nnc(N)cc3C2)ccc1Cl +Cc1ccc(NCc2c(C)nc3sc(C)cn23)cc1 +CCNC(=O)CNCc1ccc(OC)c(OC)c1 +CC(Cn1cccn1)C(=O)N1CCCC1c1cnn(C)c1 +NC(=O)CNC(=O)c1ccc2nc3ccccc3c(=O)n2c1 +CC(C)(C)c1ccc(CCC(=O)NCCCO)cc1 +CCOc1cc(NC(=O)c2ccccc2C)c(OCC)cc1N +CCn1c(=O)c2nscc2n(CC(=O)Nc2cccc(C)c2)c1=O +N#Cc1ccsc1NC(=O)COC(=O)c1ccc2c(c1)OCO2 +CC(=O)NCCNC(=O)c1cc2c(s1)-c1ccccc1OC2 +Cc1cc(F)ccc1CCNC(=O)c1ccc(-n2ccnn2)cc1 +CCNS(=O)(=O)c1ccc(C(=O)NC2CCCC2)cc1 +O=C(Cc1c(F)cccc1F)OCCCn1cccn1 +Cc1cc(NC(=O)c2occc2C)ccc1S(N)(=O)=O +O=C1CN(C(=O)C2CCOCC2)c2ccccc2N1 +CC(=O)c1cc(C(=O)Nc2ccc(OC(C)C)cc2)n(C)c1 +Cc1ccc(N(C(C)C(=O)N2CCCC2)S(C)(=O)=O)cc1C +O=C(Oc1cccc(N2CCCC2=O)c1)c1cc(-c2ccccc2)no1 +COC(=O)CCN1CCN(c2nnnn2-c2ccccc2)CC1 +Cc1ccc2c(c1)-c1c(c(C(=O)N3CCN(C)CC3)nn1C)CS2 +O=C(Cc1cccc(F)c1F)Nc1ccc(CN2CCOCC2)cn1 +Cc1cccc(CNC(=O)c2ccnc(OCc3ccccc3)c2)n1 +CSc1ccc2nc(N3CCN(C(=O)C4CCC4)CC3)sc2c1 +Cc1ccn(CCC(=O)NCC2COc3ccccc3C2)n1 +CCn1cc(C(=O)Nc2ccc(F)cc2Br)cn1 +Cc1noc(CN2CCN(C(=O)c3cc(F)ccc3F)CC2)n1 +COCCOC(=O)c1sc2nc(C3CC3)[nH]c(=O)c2c1C +Cn1cc(CCNc2cncc(Br)c2)cn1 +CCC(C(=O)NC1CC(C)(OC)C1(C)C)N1CCCC1=O +Cn1cc(NC(=O)Nc2ccc(C(=O)NC3CC3)cc2)cn1 +Cc1c(C(=O)OCC(=O)N2CCCCC2C)oc2ccccc12 +CCc1nnc(-c2ccc(NCc3ccc(C)o3)cc2)o1 +COc1cc(C(=O)C(C#N)c2nc(C)cc(C)n2)ccc1C +CCC(=O)N1CCN(CC2=Cc3cc(Cl)ccc3OC2)CC1 +Cn1c(C(F)(F)F)nc2cc(C(=O)C3CC3)ccc21 +NC(=O)c1ccc(Cl)c(NC(=O)C2CC=CC2)c1 +CCOc1cc(C#N)ccc1OS(=O)(=O)c1ccccc1F +CC(C)Oc1cc[nH]c(=NS(C)(=O)=O)c1OC1CC1 +CCc1ccc(OCC(=O)NCC(C)N2CCOCC2)cc1 +COc1cc(CNC(=O)c2cccc(C#N)c2)cc(OC)c1 +COC(=O)Cc1ccc(OS(=O)(=O)c2ccccc2F)cc1 +COCc1cccc(CNC(=O)N2CCOCC2CC(C)C)c1 +COc1ccc(Br)cc1-c1nc(C)no1 +O=C(COc1ccccc1)N1CC2COCC2(COCC2CC2)C1 +CC(C)n1cnnc1S(=O)(=O)Cc1cc(-c2cccs2)on1 +CNC(=O)NC(C)(C)C(=O)NC(C)c1ccccc1Cl +Cc1csc(NC(=O)c2ccn(-c3cccc(Cl)c3)n2)n1 +Cc1cc(C(=O)Nc2nnc(C3CCCCC3)o2)nn1C +COc1ccc(Cl)cc1NC(=O)COc1ncnc2ccccc12 +Cc1cccc(NC(=O)NCC2(C)CCCC2)c1C(=O)N1CCCC1 +CC(C)(CNC(=O)c1sccc1C#N)c1ccncc1 +CCn1nc(C)cc1C(=O)Nc1nc2n(c1C#N)CCS2 +CCC(C)n1nccc1NC(=O)C(C)c1ccsc1 +Cc1ccccc1SCC(=O)Nc1nccs1 +CC1(CC(=O)NCc2csc(=O)[nH]2)CCCCC1 +CCN(CC)C(=O)c1ccc(SC)cc1OC +C=CCCC1NCCc2cc(Cl)c(Cl)cc21 +CC(=O)Nc1cccc(NC(=O)N2CCOC(C)(C)C2)c1C +O=C(NCC(F)(F)F)C1CCCN1c1nc2ccccc2s1 +O=C(CSc1nc(-c2ccncc2)n[nH]1)c1ccc(Cl)cc1 +CCOC(=O)Cc1csc(NC(=O)c2ccoc2)n1 +COC(=O)c1sc(NC(=O)c2snnc2C)nc1C +Cc1cc2nc(C)c(=O)n(CC(=O)NCc3ccccc3)c2cc1C +COc1ccc(NC(=O)c2cc(Br)c[nH]2)c(Cl)c1 +CC(O)c1cn(C2CCN(C(=O)CCc3ccco3)CC2)nn1 +CCc1c(C(=O)NCc2cscn2)cnn1-c1ccccn1 +COc1cccc(CC(=O)Nc2ccccc2-c2nncn2C)c1 +CCC(C)CNCc1nc2cc(Cl)ccc2c(=O)[nH]1 +c1cnc(N2CCCC3(C2)CN(c2nccs2)CCO3)nc1 +CC(O)CCc1ccc(Oc2ccc3nnnn3n2)cc1 +O=C(Nc1cccc2ccccc12)c1c[nH]c2c(F)cccc2c1=O +Cc1cc(NC(=O)CCCCC(=O)Nc2cc(C)n[nH]2)[nH]n1 +O=C(Cn1nnc(-c2cccs2)n1)NCCC1=CCCCC1 +CS(=O)(=O)c1ccccc1-n1cc(NCc2cccc(O)c2)cn1 +Cc1ccc(C(C)NC(=O)NCC(C)(O)c2cnn(C)c2)cc1F +CCn1nc(-c2ccc(Cl)cc2)cc1C(=O)OC +CCC(CC)C(=O)N1CCN(CC)c2ncccc21 +O=C(CCSc1ccccn1)Oc1cc(F)cc(F)c1 +Cc1noc(C)c1CC(C)NC(=O)NCc1ccc2c(c1)OCO2 +CCOc1nccnc1N1CCN(C(=O)C2CC2)CC1 +Nc1c(Nc2ccc(F)c(F)c2)ncnc1Oc1cccnc1 +Cc1nc(Cc2nnc(SC(C)c3nc(C4CC4)no3)o2)cs1 +O=C(Cc1ccc(F)c(F)c1)NC1CCCCC1 +Cc1nc2cc(NCc3c[nH]nc3C)c(N)cc2s1 +CN(CCc1ccc(F)cc1)C(=O)c1[nH]nc2c1CCCC2 +Cc1cc(CNC(=O)CCCc2c[nH]c3ccccc23)c(C)o1 +CCCN(C)c1ccc(C(=O)N2CCOCC2C2CC2)cc1 +CCCn1ncc(-c2nc3c([nH]2)c(-c2ccccn2)nn3C)c1C +Nc1cc(NC(=O)c2ccsc2)c(F)cc1F +CN(C)C(=O)C(Cc1ccccc1)c1cccc(N)c1 +Cc1nn(C)c(C)c1CC(C)NC(=O)NC1CCCCC1O +CCC(C(=O)N(C)Cc1cc(COC)[nH]n1)n1cccn1 +Cc1ccc(OCC(O)Cn2nc(-c3ccccc3)oc2=O)cc1 +O=C1CN=C(c2ccccc2F)c2cc(Cl)ccc2N1CCO +O=S(=O)(C1CC1)N1CCOC2CC(COc3ccccn3)CC21 +COCCOCC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +COc1ccc(CCC(=O)NC2CC(=O)N(c3ccccc3)C2)cc1 +NC(=O)C1CCN(C(=O)c2cnc(C3CCCO3)s2)CC1 +CCn1c(-c2ccccc2OC)ccc(CC#N)c1=O +COc1cccc(C(=O)OCC(=O)NCc2ccccc2)c1 +Cc1ccc(-n2cnnc2)cc1-n1ccnc1C(C)c1ccccc1 +CNC(=O)c1n[nH]c2c1C(c1cc(OC)c3c(c1)OCO3)CC(=O)N2 +O=C(Cc1cccc(F)c1)NCC1COc2ccccc2O1 +CCc1nnc(NC(=O)Cc2ccc(C)cc2)s1 +O=C(Nc1ccc(F)cc1F)c1cnn2c(-c3ccco3)ccnc12 +Cn1c(N)c(C(=O)COC(=O)C2CC2)c(=O)n(C)c1=O +CC(C)CCN(C(=O)c1ccc(CNC(N)=O)cc1)C1CC1 +O=C(NCc1ccncc1)C1(c2cc(-c3ccco3)on2)CC1 +Cc1c(S(=O)(=O)NCc2ccc(F)cc2)cnn1C +CN1CCCC2(CCN(S(=O)(=O)c3cccc(C#N)c3)C2)C1=O +Cc1ccc(NC(=O)c2nc3c(s2)CCCN3C(=O)C2CC2)cn1 +CS(=O)(=O)c1cccc(N2CCN(CC3CCCCC3)C2=O)c1 +O=C(N1CCCC1)N1CCC2(CCN(Cc3cccc(F)c3)C2=O)C1 +Cc1cc(C(=O)NCC(O)C2CC2)nn1-c1ccccc1Cl +Cc1noc(C)c1CCC(=O)NCc1cccc(C#N)c1 +Cc1ccc(F)c2c1CCCN2C(=O)Cn1ccc(=O)n(C)c1=O +CCN(c1ccc(C(=O)N(C)Cc2nnc3n2CCC3)cc1)C(C)C +CCCn1c(-c2ccc3c(c2)OCCO3)ccc(C#N)c1=O +Cc1ccc(C)c(S(=O)(=O)C(C)C(=O)N2CC(C)OC(C)C2)c1 +CC(C)(CNC(=O)C1CCOCC1)c1ccccc1 +CC(C)(C)CCNC(=O)c1ccc(NC2CC2)nc1 +Cc1noc(C2CCCN(C(=O)C(C)(C)C)C2)n1 +CCn1cnnc1CNC(=O)NCC1CCN(c2ccc(F)cc2)C1 +COc1cc(F)c2c(c1)C(c1ccccn1)NCC2 +CNC(=O)c1cnc(-c2ccc(OC)c(Cl)c2)nc1N +CCC(C)C(=O)Nc1nnc(C2CC(=O)N(c3ccccc3)C2)s1 +CCCc1nnc(NC(=O)c2cc(C(C)(C)C)nn2C)s1 +CCCC(C)(CO)NC(=O)NCC1(c2ccccc2)CCC1 +CCc1ccc(-n2cc(C(=O)NCc3cccnc3)nn2)cc1 +O=C(NCCNC(=O)N1CCCC1)c1ccccc1 +O=C(Nc1cccc(OC2CCCC2)c1)NC1CC1 +O=C(CC(c1ccccc1)c1ccccc1)NCCCO +COc1ccc(CCC(=O)N2CCC(CC(N)=O)CC2)cc1OC +Cc1nc(C(C)(C)NC(=O)Nc2cnc(C(C)(C)C)nc2)sc1C +Cc1ccc(C(=O)Nc2ccc(C(=O)N3CCCCC3)cc2)o1 +CC1COCCN1C(=O)CN(C)S(C)(=O)=O +COC(=O)CCNC(=O)Cn1nnc2ccccc2c1=O +Cc1cccc(C)c1N1CCC(C(=O)Nc2ccccc2)C1=O +COc1ccc(CCNC(=O)c2c(C)nn(-c3ccccc3)c2C)cc1 +Cc1cc(-c2nnc(SCC(=O)Nc3nncs3)o2)no1 +O=C(c1cccc(-c2ccoc2)c1)N(CC(F)(F)F)C1CCC1 +CC1(C(=O)Nc2ccc(C(N)=O)cc2)Sc2ccccc2NC1=O +CN(Cc1ccncc1)S(=O)(=O)c1cn(C)nc1N +Cc1cc(C)n2nc(SC(C)C(=O)NCc3cccs3)nc2n1 +Cc1ccc2c(c1)c(CNC(=O)c1ccc(-n3cnnc3)cc1)nn2C +CCOc1ccc(F)c(C(=O)N(C)CCC(F)(F)F)c1F +CC(=O)c1cccc(NC(=O)CCC(=O)c2cc(C)ccc2C)c1 +CN1C(Cc2ccccn2)C(O)c2ccccc2S1(=O)=O +Cc1ccc2oc(C(=O)Nc3ccc(Br)cc3F)cc2n1 +O=C(CSc1cc(Cl)ccc1Cl)NCc1csc(=O)[nH]1 +CC(=O)c1nc2cccnc2n1-c1ccc(C#N)cn1 +Cc1nn(C)c(C)c1C(=O)N1CCN(CCOc2ccccc2)CC1 +CS(=O)(=O)c1ccc(Cl)c(NC(=O)CC2CC3CCC2C3)c1 +C=CCNC(=O)NCCc1coc(-c2ccccc2)n1 +CC1(CNC(=O)c2cc(S(N)(=O)=O)ccc2Cl)CCCC1 +O=C(CN1CCOCC1)Nc1cccc(NC(=O)c2ccccc2)c1 +CNC(=O)c1ccc(Cl)c(NC(=O)c2ccc(C#N)cc2)c1 +C#Cc1cccc(N(CC)C(=O)Cc2csc(-c3ccoc3)n2)c1 +C#CCOc1cc(F)ccc1NC(=O)NCc1cnn(C)c1C +CC1CCCN(c2ncnc(NC(C)(C)C)c2N)C1 +O=C(NCCc1ccc(F)cc1)c1cn(Cc2ccccc2)nn1 +CCc1nn2c(CO)c(-c3cc(OC)ccc3OC)nc2s1 +Nc1cc(Br)cc(C(F)(F)F)c1N +Cc1ccc(-c2ncc(C(=O)NCCNC(=O)C(C)C)c(=O)[nH]2)cc1 +O=C(CN1CCN(CC(O)c2cccs2)CC1)NC1CC1 +O=C(NCc1ccc(Oc2ccc(F)cc2)nc1)c1n[nH]c(=O)[nH]1 +CCOc1ccc(-c2nnc(NC(=O)C(C)(C)C)o2)cc1OCC +O=C(Cc1csc(-c2ccco2)n1)Nc1cc[nH]n1 +CC(Nc1nccc(-c2ccncc2)n1)c1ccc(-n2cncn2)cc1 +COCc1nc2nccc(-c3ccc(C)cc3)n2n1 +Cc1cc(N2CCC(c3nccnc3Nc3ccccn3)CC2)ncn1 +Cc1cc(CN(C)C(=O)CCCc2nc(-c3cccs3)no2)no1 +NC(=O)c1oc2ccccc2c1NC(=O)CC1CCCC1 +O=S(=O)(NCCCn1cccn1)c1ccc2ccccc2c1 +COc1cc2c(cc1OC)CN(c1nc(C)ns1)CC2 +CCC(C)n1ncc(C(=O)N(CC)Cc2ccccn2)c1C1CC1 +O=C(Nc1nnc(-c2ccsc2)o1)c1ccc(Cl)cc1 +CCOc1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)c2)cc1 +O=C(Cn1c(=O)oc2ccccc21)Nc1c[nH]ccc1=O +Cc1c(F)cccc1NC(=O)Nc1ccc(S(N)(=O)=O)cc1 +CN(CCN(C)C(=O)c1ccnnc1)C(=O)OC(C)(C)C +CN(Cc1ccc(C#N)cc1)C(=O)NCCc1nc2ccccc2[nH]1 +CCc1nc(COc2cccc(Cl)c2C#N)n[nH]1 +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1ccc[nH]1 +Cc1ccccc1-n1ccnc1S(=O)(=O)Cc1nnnn1C1CC1 +O=C(CCC1COc2ccccc2O1)Nc1ccc(Cl)cc1 +CCC(=O)N1c2ccccc2-c2nnc(SC)nc2OC1CC +O=C(Nn1cnc2ccccc21)C(O)(c1ccccc1)c1ccccc1 +O=C(CCCOc1cccc(Br)c1)NCc1ccoc1 +O=C1Nc2cc(F)ccc2C1NCCc1ccccc1 +CCCCC(=O)Nc1ccc(C(=O)N(C)Cc2ccccc2)cc1 +CC(C)NC(=O)NCC1(c2ccc(Cl)cc2)CC1 +Cc1noc(C)c1COc1ccccc1C(=O)NCC(N)=O +Cc1cc(C)n(Cc2nc(-c3ccccc3)cs2)c(=O)n1 +CCCCn1c(N)c(N(CC)C(=O)CC2CCCC2)c(=O)[nH]c1=O +Cc1cc(N2CCN(Cc3ccccc3)CC2)nc(-c2cccnc2)n1 +CC(C)n1nccc1NC(=O)c1cc2ccccc2oc1=O +COC(=O)CCC1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +COC(C)C(=O)Oc1ccc2c(C)cc(=O)oc2c1 +Cc1cccc(OCCNC(=O)Cn2ccc(C(F)(F)F)n2)c1 +COc1ccc2oc(-c3ccc(NC(=O)c4cccnc4)cc3)nc2c1 +C=C(C)CN(CC)C(=O)NCc1ccccc1S(=O)(=O)N(C)C +C=CCc1cc(-c2nc(C(C)(C)OC)no2)cc(OC)c1OC +COc1cccc(NC(=O)CNC(=O)c2cccs2)c1 +CCOc1ccccc1-c1nnn(-c2ccccc2C)c1N +O=C(C1CC1)N1CCCC(C2=NS(=O)(=O)c3ccccc3N2)C1 +COC(=O)c1cc(F)ccc1CN1C(C)COCC1C +O=S(=O)(c1cccnc1)N1CC2CCC1CN(c1ncccn1)C2 +N#Cc1cccc(CNS(=O)(=O)Cc2ccccc2F)c1 +COC(=O)CN(C(=O)c1cc(C)nc2onc(C)c12)C(C)C +Cc1cc(NC(=O)NCc2nc(-c3ccc(Cl)cc3)no2)n(C)n1 +CNC(=O)c1cnc2n1CCN(C(=O)c1ccccc1F)C2 +CN(c1cccc(C(=O)NC2CC2)c1)S(C)(=O)=O +N#Cc1cc(NCC(=O)NCC(F)(F)F)ccc1Cl +O=C(Nc1ccn(-c2ncccc2Cl)n1)c1ccccc1F +Cc1cc(NC(=O)c2ccc(S(=O)(=O)C(C)C)cc2)n(C(C)C)n1 +CC(=O)Nc1ccc(CNS(=O)(=O)Cc2ccc(F)cc2)cc1 +CCC(C)NC(=O)C(C)NC(=O)c1ccccc1F +CC1CCC(N(C(=O)CSc2nncs2)C2CC2)CC1 +CCn1cnnc1CNC(=O)c1nn(C(C)C)c(=O)c2ccccc12 +C=CCOc1ccc(C2NC(=O)c3ccccc3N2)cc1OCC +CN(C)C(=O)c1ncc(S(N)(=O)=O)cc1OC1CC1 +CCC(=O)NCC(O)c1ccc(C2CCCCC2)cc1 +CC(C)(CO)NS(=O)(=O)c1c(Cl)cc(N)cc1Cl +Nc1ccc(NC(=O)c2cc(F)ccc2F)c(Cl)c1 +CCN(CCCO)S(=O)(=O)c1ccc(Cl)c(C)c1 +CC(CN1CCOCC1)Nc1ccc(Cl)cc1N +O=C(Cn1cnc2cc(F)ccc2c1=O)N(C1=CCCCC1)C1CC1 +CNc1ccccc1S(=O)(=O)Nc1ccc(F)cc1 +COc1ccc(CNc2ccc(N3CCCC3=O)cc2)cc1F +Cc1nnc2n1CCN(C(=O)C(C)Oc1cccc(C#N)c1)C2 +COc1ccc(C(=O)N2CCC(N3CCNC3=O)CC2)cn1 +CC(=O)c1ccc(NC(=O)Cn2nc(-c3ccccc3)ccc2=O)cc1 +O=C(CC1C=CCC1)N1CC2OCCN(Cc3ccccc3)C2C1 +N#Cc1ccc(CCOc2ccc3c(c2)OCO3)cc1 +COc1ccc(Cc2nnc(NC(=O)c3cccnc3)s2)cc1 +COc1cccc(-c2cc(=O)c3c(O)cc(O)cc3o2)c1OC +Cc1ccc(-n2nnnc2SCC(F)(F)F)c(C)c1 +CN(C)C(=O)C1CC(=O)N(C)C1c1cccs1 +CCOCCC(=O)Nc1cc(C(=O)N(C)C(C)C)ccc1Cl +C#CCN1CCC(C(=O)Nc2nc(-c3ccccn3)cs2)CC1 +COc1ccc(C(=O)Nc2ccnc(C)c2)cc1OC +COCCOc1ccc(F)cc1NC(=O)NCc1ncc[nH]1 +CC1CCC(N(C)C(=O)COc2ccccc2C(N)=O)CC1 +CCn1c(=O)c2ccccc2n(CC(=O)Nc2ccc(F)cc2)c1=O +COc1ccccc1C(C)NC(=O)Cn1cnc2sccc2c1=O +CCOc1ccc(C(C#N)CC(=O)N2CCCCC2)cc1 +Cc1cc(C)n(C(=O)COc2nc3ccccc3s2)n1 +c1ccn2c(Cn3cc(-c4ncc[nH]4)nn3)nnc2c1 +NC(=O)c1cccc(NCC(=O)Nc2cccc(Cl)c2)c1 +COCc1c(CO)nnn1Cc1ccc(Cl)c(Cl)c1 +CCOc1ccc(C(=O)Nc2ccc(C(N)=O)c(Cl)c2)cc1OC +Cc1noc(C)c1CN(CCO)Cc1cccnc1 +CC(C)NC(=O)N1CCc2nc(-c3ccccc3)ncc2C1 +O=C(Nc1nc2c(s1)COCC2)C1CCCC1 +CN(Cc1ncon1)C(=O)C1(c2cccs2)CCCCC1 +CC(=O)Nc1ccc(NC(=O)Nc2ccc(C)c(C)c2)cc1 +CC(C)(CNC(=O)C1(c2ccc(F)cc2)CC1)C(N)=O +CC1Cc2ccccc2N1C(=O)COC(=O)c1ccccn1 +CCCCN1C(=O)C2(OCCO2)c2cccc(C)c21 +CC(=O)Nc1ccc(OC(=O)C(C)Oc2ccccc2)cc1 +NC(=O)c1ccccc1OCC(=O)Nc1cccc2ccccc12 +Cc1ccncc1NC(=O)NC1CCN(c2ncccc2Cl)C1 +CC(C)NC(=O)Nc1cccc(C(=O)Nc2ccc(N(C)C)nc2)c1 +CCNC(=O)CNC(=O)NCCc1csc(-c2ccccc2)n1 +Nc1cc(Cl)ccc1C(=O)N1CCCCC1CCO +C#CCN1CCN(C(=O)c2cc(F)ccc2Br)CC1 +COC(=O)c1cc(C(=O)OC)cc(-n2nnc(C(C)=O)c2C)c1 +CCCC1Nc2ccccc2N(C(C)C(N)=O)C1=O +C#CCN(Cc1ccc(C)cc1)C(=O)CCc1c(C)[nH]c(=O)[nH]c1=O +Cc1cccc(S(=O)(=O)Nc2ccc(=O)n(C)c2)c1 +Cc1ccc(COC(=O)c2cc(S(C)(=O)=O)ccc2C)cc1 +CCN(CCC(=O)OC)C(=O)c1ccc(F)cc1Br +FC(F)(F)c1ccc(CN2CCOCC2c2ncon2)cc1 +COc1ccccc1OCCNC(=O)c1cc2c(cn1)OCC2 +COC(=O)c1ccccc1Oc1ncnc2sccc12 +CCn1nc(C)cc1C(=O)Nc1sc(C)c(C)c1C(=O)OC +Cc1ccc(C(=O)NCC(=O)NCCCN2CCOCC2)cc1C +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1n[nH]c(=O)c2ccccc12 +Cc1nc(C(=O)NC2CCN(S(C)(=O)=O)CC2)cs1 +Cc1noc(COC(=O)CNC(=O)Cc2cccc(F)c2)n1 +O=C(Cn1cnnn1)Nc1ccc(C(=O)Nc2nccs2)cc1 +Cc1nc(CN(C)c2nc3c(s2)C(O)CCC3)cs1 +OCCCc1nc2ccccc2n1-c1ccc(O)c(-c2ccno2)c1 +Cc1cc(NC(=O)CN(C)S(=O)(=O)c2c(C)noc2C)no1 +CCc1ccc(CC(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1cc(C)cc(C)c1 +c1cnc(-n2cc(NCc3ccccc3OCC3CC3)cn2)nc1 +Cc1ccc(S(=O)(=O)N(C)c2ccc(O)cc2)c(C)c1 +COc1cccc(NC(=O)CSc2nnc(-c3cccs3)o2)c1 +CC(=O)NCCCS(=O)(=O)c1ccc(Br)cn1 +Cc1nc(-c2ccc(CC(=O)N3CCCC(O)C3)cc2)cs1 +Cc1cccnc1NC(=O)c1ccc(F)c(S(=O)(=O)N2CCC2)c1 +Cn1cccc1C1COCCN1C(=O)c1cc(-c2ccccc2)[nH]n1 +Cc1ccc(NC(=O)N(CCO)Cc2cccnc2)s1 +NC(=O)CCCNC(=O)CCc1ccccc1Cl +COc1cc(C#N)ccc1OCCOc1ccc(C)cn1 +CCN(CC(=O)NC(C)C(=O)N1CCCCC1)c1ccc(C)cc1C +CCOc1ccc(N2CC(C(=O)NCc3cccnc3)CC2=O)cc1 +O=C(NCc1ccccn1)C1CCCN(C(=O)Nc2ccccc2)C1 +Cc1ccccc1-c1ccccc1-c1ncnn1CCO +O=C(NCCOc1ccccc1)Nn1cnc2ccccc21 +CCNc1c(F)cccc1C(=O)Nc1ccn(C)n1 +CC1CN(CC(=O)NC2CCOCC2)CC(c2ccccc2)O1 +Cc1ccccc1OCCCC(=O)N(C)C(C)c1ccncc1 +CCc1cnccc1C(=O)OC1CCN(c2ccncn2)CC1 +Cc1noc(C)c1C(C)NC(=O)Cc1ccc(OC(F)F)cc1 +COC(=O)CCNc1cnn(Cc2ccccc2)c1 +Cc1ccsc1-c1nc(Cn2c(CO)nc3ccccc32)c(C)o1 +CC1Oc2ccc(N)nc2N(Cc2ccccc2F)C1=O +CCC(Nc1cc(C(F)(F)F)nc2ncnn12)C(C)C +CCn1nnnc1SCCn1c(=O)oc2ccccc21 +CC(=O)N(CCc1ccccc1)CC(=O)NC1C=CCCC1 +COc1ccc(C(=O)CNC(=O)c2ccccc2C)cc1OC +CC1(Cc2ccccc2)OCC(CCCCO)O1 +Nn1nc(-c2cccc(Br)c2)c2cc[nH]c21 +CC(Cc1ccsc1)NCc1cc(C#N)ccc1F +COc1ccc(CNc2ccc3c(c2)oc(=O)n3C)cc1 +CCc1cc(N)c2oc(C(=O)Nc3ccccn3)cc(=O)c2c1 +O=C(NCCOCc1ccccc1)c1ccc(-n2ccnn2)cc1 +CC(=O)c1ccc(NC(=O)N2CCCC2c2c(C)n[nH]c2C)cc1 +O=C(NCc1ccccc1)N1CC(c2nc(-c3ccccn3)no2)C1 +Cc1ccc(CC(=O)Nc2cccc(C(N)=O)c2C)cc1 +CC(Cn1cccn1)OC(=O)c1cn(C)nc1-c1cccs1 +O=C(c1cc2c(cc1Br)OCCO2)C1CCCCO1 +Cc1ccc(C2CN(C(=O)NCCc3cnn(C)c3C)CCO2)o1 +CC(NC(=O)NC1CCC(O)CC1)c1cnn(Cc2ccccc2)c1 +O=C1OCCN1CCC(=O)N1CCCC1C1CCCCC1 +Cc1cc(C)cc(C(=O)NCC2(O)CCOc3ccccc32)c1 +CCOc1ccc2ncc(NC(=O)NCc3ccco3)c(O)c2n1 +O=S(=O)(c1cc(F)cc(F)c1)N(Cc1ccccc1F)C1CC1 +CC(=O)N1CCCC1C(=O)Nc1ccc2c(c1)COC2 +Cc1noc(C2CCCCN2S(=O)(=O)c2cccs2)n1 +CC1CCCCC1NC(=O)CCNS(C)(=O)=O +CCCNC(=O)NCC(O)c1ccc2c(c1)CCO2 +Cc1noc(C)c1CNC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +Cn1c(SCc2nc3ccccc3s2)nnc1-c1ccco1 +O=C(NCc1cccs1)Nc1c[nH]c2ccccc12 +Cc1nnsc1C(=O)NCCC(O)C(C)(C)C +C=CCNC(=O)c1onc(S(=O)(=O)C(C)C)c1N +CN(Cc1ccc(F)cc1)C(=O)NCCN1CCOCC1 +Nc1cccc(CCC(=O)Nc2ccccc2Br)c1 +Cc1csc(CNc2ccccc2OC(C)(C)C)n1 +Cc1noc(C)c1S(=O)(=O)N1CCc2cc(F)ccc2C1 +C#CCN1CCN(CC(=O)NC(c2ccc(OC)cc2)C2CC2)CC1 +OCCc1cc(CC2(NCc3ccccc3Cl)COC2)no1 +COC(CNC(=O)Cc1cccs1)c1ccsc1 +CCOC(=O)C(O)c1nnc2c(C)cc(C)nn12 +Cc1noc(C)c1C(C)NS(=O)(=O)c1ccc(C(C)C)cc1 +COC(=O)Cc1ccc(-n2cnc3cc4c(cc32)OCCO4)cc1 +CSc1c(Cl)cccc1NC(=O)NCC1(CO)CC1 +Cc1ccc(CC(=O)Nc2cc(N(C)C)ccn2)cn1 +O=C(Nc1ccnc2ccnn12)c1ccc2ccccc2c1 +CC(C)(C)NC(=O)C1CN(C(=O)c2cccs2)C1 +COC1CCC(CC(=O)N2CCSc3ncccc32)CC1 +CCC(CC)NC(=O)c1cccc(S(=O)(=O)NC(C)C)c1 +COc1cc(CCC(=O)N2C(C)CCCC2C)cc(OC)c1OC +CC1CCC(C(N)=O)CN1C(=O)CSc1ccccc1 +COC(=O)NCC(=O)NCC(C)(C)N1CCOCC1 +Nc1cccc(CN2CCNc3ccc(Cl)cc32)c1 +CC(C)(C)OC(=O)N1CCCC(c2cc[nH]n2)C1 +CCN(C(=O)CCc1cc(N)c(OC)cc1OC)c1ccccc1 +COc1cccc(NC(=O)NCCc2c(O)n[nH]c2C)c1 +Cc1ccc(CN2CC3OCCC3C(C(=O)N3CCCC3)C2)s1 +CC(=O)N1CC=C(c2ccc(OCC(O)c3ccccc3)cc2)CC1 +Nc1c(C(=O)Nc2ccccc2F)sc2ncccc12 +CC(O)Cn1c(NCc2ccco2)nc2c1c(=O)n(C)c(=O)n2C +O=C(NCc1cccnc1)Nc1ccnc(Oc2ccccc2)c1 +Cc1cccc(NC(=O)Cn2cnc3c(nnn3C)c2=O)c1 +CC(C#N)CC(=O)NCCc1c[nH]c2ccccc12 +Cc1ccc(C(O)C(=O)Nc2ccccc2OC(C)C)c(C)c1 +O=C1CC(NC(=O)c2cnn3c2OCCC3)CN1 +CC(c1ccncc1)N(C)Cc1cnc(-c2ccccn2)s1 +Nc1cc(Br)cc(C(=O)NC2CCCCC2)c1 +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)Oc1cccc(C)c1 +CC1(Cc2ccc3c(c2)OCO3)CCCN(C(=O)Cn2cnnn2)C1 +CCCCCNC(=O)C(C)N1CCN(c2ncccn2)CC1 +Cc1csc(NC(=O)c2cccc(S(=O)(=O)NC3CC3)c2)n1 +Nc1cccc(Cl)c1SCc1nccn1C(F)F +Cc1[nH]c(=O)nc(N)c1-c1ccc(Cl)c(Cl)c1 +CN(C)c1ccc(C(=O)Nc2cc(-c3ccsc3)no2)cc1 +CCN1CCc2nc(NC(=O)c3cc(OC)cc(OC)c3)sc2C1 +Cn1cc(C(=O)N2CCCC3(CCCCCC3)C2)cn1 +Cc1ocnc1CNC(=O)Nc1ccccc1OCC1CCCCO1 +O=C(NCCCn1cc(Cl)cn1)c1ccnn1C(F)F +O=C(C1CCCCCC1)N1CCCC(Cn2cc(CCO)nn2)C1 +CC(=O)Nc1ccc(SCC(=O)N(C)CC(=O)NC2CC2)cc1 +COc1ccc2cc(CNC(=O)CC3CCCO3)ccc2c1 +CCc1nc2scc(-c3ccccc3)c2c(=O)n1N +CC(=O)c1ccc(NC(=O)c2cnn(CC(C)C)c2C(F)F)cc1C +CCOc1ncccc1C(=O)Nc1ccnn1Cc1ccc(C)o1 +O=C(Nc1nc2ccccc2s1)N1CCC2(CC1)OCCO2 +Cc1nn(CCO)c2ncc(C(=O)c3cc(F)ccc3O)cc12 +NS(=O)(=O)c1ccc(C(=O)NCc2ccc(Cl)cc2)o1 +CC(C)n1cnc2ccc(NC(=O)c3n[nH]c4c3CCC4)cc2c1=O +CC1(O)CCN(C(=O)c2cc(Cl)ccc2F)CC1O +CCOc1ccc(NC(=O)C2COc3ccccc3O2)cc1OCC +Cn1cc(-c2nnc3sc(-c4cc(C(C)(C)C)[nH]n4)nn23)cn1 +CCOc1ccc(NC(=O)Cc2csc(NC(C)=O)n2)cc1 +O=c1[nH]ncc(NCc2cc3ccccc3[nH]2)c1Cl +Cc1ccc2c(c1)NC(=O)C(CC(=O)NCCn1cc(Cl)cn1)O2 +Cc1ccc(S(C)(=O)=O)cc1C(=O)OCc1nccn1C(F)F +CCCOc1cccc(NCC(=O)N2CCCCCC2)c1 +COc1cccc2c(=O)c(NC(=O)NCCN3CCOCC3)c[nH]c12 +CCc1nnc2c(=O)n(CC(=O)NC3CCCC3)c3cccnc3n12 +CCCCN1C(=O)C(CC)Oc2c(OCC)cc(CO)cc21 +C1=CCC(c2cn(Cc3cc(-c4ccccn4)no3)nn2)CC1 +O=c1ccn(Cc2csc(-c3ccccn3)n2)c2ccsc12 +Cc1cc(NC(=O)N2CCC(OCc3ccc(F)cc3)CC2)nn1C +CC1CCCCN1C(=O)NCCc1cccc(C(N)=O)c1 +CCCS(=O)(=O)N1CCN(c2cc(N3CCCC3)ncn2)CC1 +O=C(CCc1cccnc1)Nc1ccc2c(c1)OCO2 +N#Cc1ccc(S(=O)(=O)NC(c2ccccc2)c2ccncc2)cc1 +Cn1c(C(=O)NCC(C)(C)c2ccncc2)cc2ccccc21 +N#CCSc1nccn1CCc1ccccc1F +CCOC(=O)CN(C(=O)c1ccc(C)nc1)c1ccc(F)cn1 +CN(C(=O)COC(=O)c1ccc2ccccc2n1)C1CCCCC1 +CCc1nc(SCC(N)=O)nc(N)c1-c1ccc(Cl)cc1 +COc1cc(CNC(=O)N(C)Cc2nccn2C(F)F)ccn1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)C1(c2ccccc2)CC1 +Cc1noc(C23COCC2CN(C(=O)C2CCOCC2)C3)n1 +CC(C)n1nc(C(=O)NC2CCC(=O)N(C)C2)c2ccccc2c1=O +COc1ccccc1-c1nc(-c2nnn(-c3ccccc3)c2C)no1 +COCc1cccc(NC(=O)N2CCOCC2)c1 +O=C(CCCc1cc(F)ccc1F)Nc1ccc(F)nc1 +CN(C(=O)C1CCOCC1)c1ccc2ccccc2c1 +CN(Cc1nc(-c2ccccc2)no1)C(=O)c1cn(C)c2ccccc12 +O=C(Cc1ccc(Br)cc1)NCCc1cccc(O)c1 +CCC(C)NC(=O)Cn1c2ccccc2c(=O)c2ccccc21 +COC(=O)CNc1ncc(Br)c2ccc(N)cc12 +Cc1ncccc1CN(C)CC(=O)Nc1ccc(Br)cn1 +NC(=O)c1cnc(NC(=O)CCCOc2ccc(F)cc2)s1 +COc1ccc(C(C#N)N(C)C(=O)c2cccnc2)cc1 +COCc1nc(N2CCOCC2)sc1C(C)(C)O +c1cnc(CC2CCN(c3cnccn3)CC2)cn1 +Cc1cc(C2CCCN2C(=O)c2cc(C)on2)on1 +COC(=O)C(C)CNC(=O)Nc1cccc(Br)c1C +CCN1CCN(C2=NC(=O)CC(C(=O)Nc3ccc(C)cc3)N2)CC1 +CCNc1nc(C)cc(N2CCN(C(=O)c3ccc(C)cc3)CC2)n1 +N#Cc1ccc(C(=O)Nn2cnc3ccccc3c2=O)cc1 +Cn1c(=O)c(=O)n(CC(=O)NC2CCCCC2)c2ccccc21 +O=S1(=O)N=C(NCCCc2ccccc2)c2ccccc21 +CCn1nccc1CN(C)C(=O)Cn1cc2c(n1)c(C)nn2C(C)C +COc1ccc(NC(=O)c2ccc(OCC(F)F)nc2)cc1 +CC(C)(O)CN1CCN(c2ccc(S(N)(=O)=O)cc2)CC1 +O=C(NC1CCCCC1)c1nn(-c2ccccc2)c2c1COC2 +CCCN(C1CC1)S(=O)(=O)c1cc(C)cc(N)c1 +COC(=O)c1cccc(C(=O)Nc2cc(C)on2)c1 +Cc1nc2nnc(C(=O)Nc3ccccc3)c(C)n2n1 +FC(F)(F)c1nnc(-c2ccc3ccccc3c2)nn1 +NC(=O)CN(C(=O)CCc1nc(-c2cccs2)no1)C1CCCC1 +Cc1nc(C2CCCN(C(=O)c3cscn3)C2)cc(=O)[nH]1 +O=C(c1cnns1)N1CCN(c2ccc(O)cc2)CC1 +Cc1nc(C2CC(=O)Nc3c2cnn3Cc2cccs2)co1 +COc1ccc(N)cc1CNC(=O)OCC(C)C +CCOc1ncccc1C(=O)NCc1nc2ccccc2[nH]1 +c1ccc2oc(-c3noc(CCn4cncn4)n3)cc2c1 +CC(=O)N(C)CC(=O)NC(C)COc1ccc(F)cc1F +CCCCOc1ccc(C(=O)NC2CC2)cc1OC +Cc1nc(C(=O)Nc2nc3c(C)ccc(C)c3s2)cs1 +Cc1cccc(CN2CC3(CCN(C(N)=O)CC3)OCC2=O)n1 +CCn1c(C)nc2cc(Br)c(F)c(F)c21 +NC(=O)C1(NC(=O)c2cc(S(N)(=O)=O)ccc2F)CCCC1 +CC(=O)c1ccc(NS(=O)(=O)c2cccc(F)c2)cc1 +CC(C)CCNC(=O)C1CCCCN1C(=O)c1ccccc1 +O=C(Cc1c[nH]c2ccccc12)NCCc1cccc(F)c1 +CCc1ccc(C(C)NC(C)Cc2cc(C)n[nH]2)o1 +O=C(Cc1ccc(F)cc1)N1CCC(OCc2ccc(F)cc2)CC1 +CC(C)c1cccc(NC(=O)c2ncccc2O)c1 +COc1cc(CNC(=O)c2cccnc2)ccc1OCC(N)=O +Cc1c(NC(=O)Cc2ccc(F)cc2)c(C(=O)N(C)C)nn1C +CC(C(=O)Nc1ccccc1F)N1CCN(c2ncccn2)CC1 +CC(Sc1ccc(Cl)cc1)C(=O)NC(C)(C)C#N +CC1CCc2c(C(=O)NCC(C)(C)N3CCOCC3)csc2C1 +CC(C)(C)NC(=O)COCc1cc(-c2ccc(F)cc2)on1 +CC(C)(C(=O)Nc1nnc(-c2ccccn2)s1)c1cccs1 +CCc1onc(C)c1NC(=O)NCCCOC1CCOCC1 +O=C1COc2cc(CO)ccc2N1CC(O)CO +CCOCC1CCN(C(=O)c2c[nH]nc2-c2ccccc2Cl)C1 +COc1ccccc1C(C)NC(=O)CS(=O)c1ccc(C)cn1 +Nc1nc(SCCO)[nH]c(=O)c1NC(=O)c1ccco1 +CC1=NC2(CCC3CN(C(=O)Nc4ccccc4C)CC32)C(=O)N1C +COc1cc(C#N)ccc1CNc1c[nH]ccc1=O +Cc1cccc(C(N)=O)c1NCc1csc(-c2ccsc2)n1 +CCCNC(=O)c1cccc(NC(=O)c2ccc(OCC)cc2)c1 +CCC(C)N1C(=O)c2ccccc2NC1c1ccccc1 +O=C(Nc1ncc(Cl)cc1Cl)c1cc2ncccn2n1 +COc1ccccc1Cc1nc(CCCO)cs1 +O=C(COc1ccccc1)NC1CCc2ccccc21 +COc1ccccc1CC(=O)NC1CCCC(C)C1 +CCCCS(=O)(=O)N1CCOc2c(N)cccc21 +CSc1cccc(-c2nnc(NC(=O)c3ccccc3)o2)c1 +O=C(CCC1CCCC1)N1CCN(Cc2cccs2)CC1 +CCOC(=O)c1c(C)c(C(=O)NCc2ccco2)c(C)n1C +CC(NC(=O)COc1ncnc2ccccc12)c1ccc2c(c1)CCC2 +O=C(NCCNC(=O)c1ccco1)c1cnc(-c2ccccc2)nc1 +CC1CC(Sc2nc3ccccc3c(=O)n2C(C)C)C(=O)O1 +CCn1ncc2cc(C(=O)c3ccccc3O)cnc21 +CC(NC(=O)c1nccnc1N)c1cccc(Br)c1 +CCS(=O)(=O)N1CCC(C(=O)NCc2ccccc2F)CC1 +COc1ccc(OCCCNC(=O)Nc2ccc(C#N)cc2)cc1 +CC1CCC(NC(=O)c2nn(C)cc2Br)CC1 +CCc1ccc(-c2nnn(CC(=O)Nc3sccc3C#N)n2)cc1 +O=C(CCn1cncn1)Nc1nnc(Cc2ccccc2)s1 +CCn1c(=O)oc2cc(NC(=O)NCc3nnc4n3CCC4)ccc21 +Cc1noc(C)c1CC(=O)Nc1ccc(Cn2ccccc2=O)cc1 +CC(C)N(CCCO)C(=O)CCc1cccc(N)c1 +N#CC1(C(=O)N2CCCc3ccccc32)CCCC1 +O=C(Nc1ccon1)c1cc(-c2cccs2)nc2ccccc12 +Cc1cc(C(=O)NC2CCCCNC2=O)c2ccc(C)c(C)c2n1 +CCN1C(=O)CCc2cc(NC(=O)c3ccc(F)cc3F)ccc21 +Cc1ccccc1CC(=O)Nc1cc(-c2ccco2)no1 +O=S(=O)(CCc1cccs1)c1cccc(Br)c1 +O=C(CN1CCCCC1=O)NCc1cccnc1OC1CCCC1 +Cc1c(Cl)cccc1N(CC(=O)N1CCCC1)S(C)(=O)=O +O=C(Nc1ccccc1)n1ccc(-c2ccc(-n3ccnc3)cc2)n1 +O=C(NC(c1ccccc1)C1CCC1)N1CCC2(CC1)OCCO2 +CCC1=C(C(=O)OC)C(c2cccc(OC)c2OC)NC(=O)N1CC +CCc1nnc(SCC(=O)Nc2ccccc2OC)o1 +O=C(NCc1nnc2n1CCC2)c1cnn(-c2ccccc2)n1 +COc1ccccc1-c1n[nH]c(NC(=O)C2CC3CCC2C3)n1 +CC(NC(=O)c1ccccc1)C(=O)N1CCNCC1 +NC(=O)C1CCCN(S(=O)(=O)CCCc2ccccc2)C1 +NC(=O)c1csc(C(=O)OCCCn2nc3ccccn3c2=O)c1 +COC(=O)C1CCN(C(=O)c2occc2C)c2ccccc21 +Cc1ccc(NC(=O)c2cccs2)cc1S(C)(=O)=O +CCc1cccc(C)c1NC(=O)NC(C)C(=O)NCc1ccccc1 +Cc1cc(=O)n2nc(NC3CCN(C(=O)C(C)C)CC3)sc2n1 +Cc1nnc(C(C)Sc2nc3cc(F)c(F)cc3[nH]2)o1 +CCOC(=O)COc1cccc(OC(F)(F)F)c1 +CN(Cc1ccncc1)C(=O)NCc1cccnc1OC1CCCC1 +N#Cc1cc2c(nc1SCC(=O)NC1CC1)CCCC2 +COc1ccc(-n2cc(CNC(=O)c3cccc(C)c3C)nn2)cc1 +CCn1c(Cc2ccccc2)nnc1SCC(=O)NC1CC1 +CNC(=O)c1ccc(CNC(=O)Cc2ccc[nH]2)cc1 +Cc1cc(C)n(Cc2ccc(OC(F)F)cc2)n1 +CCN(CC)C(=O)c1cccc(NC(=O)c2ccccc2O)c1 +CC(C)(C)Oc1cc(CNC(=O)c2ncoc2C2CCCO2)ccn1 +COC(=O)c1cnn(-c2ccc(C(=O)NC3CCCCC3)cc2)c1N +CCOC1CCCN(C(=O)Nc2cccc(OCC3CCCO3)c2)C1 +O=C(CC1CCCCC1)N1CCCC(c2nnc3ccccn23)C1 +Cc1cc(C)n(CC(C)CNC(=O)c2ccc3c(c2)OCO3)n1 +Cc1cnn(CC(=O)NCCOc2ccccc2C)c1 +Cc1ccc(NC(=O)NCC2(O)CCOCC2)cc1 +CCCNC(=O)Nc1ccc2c(c1)oc(=O)n2CCC +Cc1cc(C)n(CC(=O)Nc2ccc3c(c2)OCO3)n1 +CC(C)NC(=O)NC1CCC(c2ccccc2)CC1 +O=C(C1COCCO1)N1CCCC(c2nc3ccccc3o2)C1 +NC(=O)Cc1csc(NC(=O)CSc2ccccc2Cl)n1 +O=C(c1cccc(S(=O)(=O)N2CCCCC2)c1)N1CCCCC1 +CN(C)C(CNC(=O)CCC1CCCCO1)c1c(F)cccc1F +c1cnc2nc(CSc3ncnc4sc5c(c34)CCC5)cn2c1 +CC(C1CC1)N(C(=O)Cn1ncnc1-c1cccc(C#N)c1)C1CC1 +COCCn1cc(NS(=O)(=O)c2ccc(Cl)cc2)cn1 +Cc1ccc(CC(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1 +CCC(NC(=O)Cc1ccccc1)C(=O)N1CCNCC1 +CCn1ccc2cc(CN3CCOC(CCNC(C)=O)C3)ccc21 +Cc1cc(C)nc(CN2CCCCC2CCN2CCOCC2)n1 +Cc1nc2ccc(Cl)cn2c(=O)c1NC(=O)c1ccc(F)cc1F +OCC1(CSc2nnc(-c3ccc(Cl)cc3)o2)COC1 +O=c1[nH]c2ccc(NS(=O)(=O)Cc3ccccc3)cc2s1 +NC(=O)Cn1c(CNC(=O)C2CCCCC2)nc2ccccc21 +O=C(CNC(=O)c1ccccc1C(=O)c1ccccc1)NC1CC1 +CC(C)CCOC(=O)Cn1c(CO)nc2ccccc21 +Nc1ccc(NCCCNC(=O)NC2CCCCC2)nc1 +CC1CCN(S(=O)(=O)c2ccc(NC(=O)C3CC3C)cc2)CC1 +CC(C)C(=O)NCC(O)c1ccc(Br)cc1 +COc1ccccc1CN1CCC(c2nnc(C(C)(C)C)o2)C1 +COC(=O)c1c(NC(=O)c2cccc(-n3cnnn3)c2)c(C)nn1C +Cc1ccc(OCc2nnc(C3CCC3)o2)c(C(=O)NCC(C)C)c1 +Cc1cc(Nc2ncc(N)cc2Br)no1 +C#CCN(Cc1ccco1)C(=O)c1csc(COC)n1 +N#Cc1cccnc1NCC(C1CCOC1)N1CCOCC1 +Cc1ccccc1OCCCn1nnc(-c2ccc(C(N)=O)cc2)n1 +CC(=O)NCCc1nc2cc(NC(C)=O)ccc2n1C +COC(=O)c1ccc(NC(=O)NCc2noc3ccccc23)cc1 +Cn1ncc2c(=O)n(CCC(=O)N3CCCC4CCCCC43)cnc21 +Cc1cc(C(=O)NCCc2ccc3c(c2)OCO3)on1 +NC(=O)C1CCCN(C(=O)c2ccccc2OC(F)F)C1 +C#CCOCC1CCCN(C(=O)CSc2nnnn2C)C1 +O=C(Cn1cccn1)N1CCC(Oc2cnc3ccccc3n2)CC1 +Cn1cnnc1SCc1cc(Br)ccc1Cl +Cc1ccc(C(=O)Nc2ccc(Cl)c(N)c2)cc1O +O=C1NC(c2ccc(F)cc2F)Nc2ccc(Cl)cc21 +CCc1ccc(OCC(=O)Nc2ccc3oc(=O)[nH]c3c2)cc1 +CN(Cc1cnccn1)C(=O)NCCc1csc(N2CCCC2)n1 +COc1cc(NC(=O)C2CC(=O)N(C)C2c2ccc(F)cc2)ncn1 +Cc1ncsc1C(=O)Nc1cccc(-n2cnnn2)c1 +COCCNc1nc(-c2cc(F)ccc2F)ccc1C#N +CC1CN(c2ccc(C#N)cn2)CCN1c1ccc2nncn2n1 +O=C(Cc1cc(Cl)c2c(c1)OCCO2)N(Cc1ccco1)C1CC1 +Cc1nn(C)cc1CN1CCN(C(=O)Cc2c(C)noc2C)CC1 +CCSc1ccccc1C(=O)NCCc1ccoc1 +Cc1nc2ccc(NC(=O)c3cccc(Br)c3)cc2[nH]1 +O=C(NCc1ccco1)c1csc(-n2cccc2)n1 +OCc1c(-c2ccco2)nc2sc(-c3cccs3)nn12 +CCC(C(=O)Nc1ccccc1C)N1C(=O)CCn2nc(C)cc21 +CCc1cc2c(=O)n(NC(=O)c3ccco3)cnc2s1 +Cc1ccccc1C(=O)N1CCCCC1C1OCCO1 +COC(=O)c1cccc(OS(=O)(=O)c2c[nH]ccc2=O)c1 +Cc1cc(CN2CCN(C(=O)NC(C)c3ccccc3C)CC2)no1 +CC(CCCO)NC(=O)N(C)C1CCCN(c2ccccc2)C1=O +CN(C(=O)C1CCCN1C(=O)c1ccco1)c1ccccc1 +CCCCN(Cc1ccccc1F)C(=O)c1cc(C)nn1C +FC(F)(F)Oc1ccc2c(c1)C(c1cnccn1)NCC2 +COc1cc(C(=O)N2CCOCC2CC(C)C)cc(Cl)c1OC +Cc1ccc(S(=O)(=O)c2cc3ccccc3nc2N)cc1 +CCOC(=O)CN(C(=O)c1ccnc(-n2cncn2)c1)C1CC1 +O=C(Nc1nc(C2CC2)cs1)c1ccc2c(c1)CCCN2 +CC(=O)c1c(C)nc(C)nc1SCc1cnn(-c2ccccc2)n1 +CCN(CC)C(=O)c1nccc2c(N)c(C)ccc12 +Cc1nc(C)c(-c2nnc(SCc3n[nH]c(=O)[nH]3)o2)s1 +COc1ccc(CNC(=O)NCCC(=O)N2CCCCCC2)cn1 +CC(C(=O)N(C)C(C)c1ccc(-n2cncn2)cc1)c1cccs1 +COc1ccc(CC(=O)N2CCC(O)CC2)c(OC)c1C +Cc1cc(Br)cc(S(=O)(=O)N2CCOCC2)c1 +CCCn1c(SC(C)C(=O)NCC(F)(F)F)n[nH]c1=O +CC(C)C(C)NC(=O)C1CCN(c2ccc(F)c(F)c2)C1=O +CN(C)C(=O)CN1CCN(c2c(F)cc(C#N)cc2F)CC1 +CCN(C(=O)CC12CC3CC(CC(O)(C3)C1)C2)c1ccccc1 +COc1cc(S(=O)(=O)NC2CCCCC2)ccc1F +Cc1ccc(SCC(=O)N(C(C)C)C2CCOCC2)cc1 +O=C(c1ccc2nccnc2c1)N1CCC(Cc2ccccc2)CC1 +Cc1cnc(NC(=O)c2oc(C)nc2C)c(Br)c1 +CNC(=O)Cc1ccc(NC(=O)CN(C)C(C)=O)cc1 +CC(C)Cc1ccc2nc(-c3nccs3)c(=O)n(C3CC3)c2n1 +C=CCn1cnc2c(sc3nc4c(cc32)COC(C)(C)C4)c1=O +Cc1ccc(NC(=O)C2COCCO2)c2[nH]ncc12 +Cc1cc(C(=O)Nc2ccccc2S(=O)(=O)N2CCCC2)n(C)n1 +CCOc1ccc(F)c(C(=O)OCc2ccc3nn[nH]c3c2)c1F +Cc1nc(-c2ccc(CNC(=O)c3ccccc3Cl)cc2)cs1 +Cc1cc(C)c(C(=O)NCC(O)CN2CCOCC2)[nH]1 +COC(=O)N1CCN(c2cc(C(C)C)nc3cc(C)nn23)CC1 +CN(CCO)C(=O)Cc1csc(-c2ccccc2N)n1 +CC(=O)N1c2ccc(S(=O)(=O)NC3CCCCC3)cc2CC1C +COc1ccccc1CNC(=O)c1cccnc1OCC(F)F +CCCOC1CCCN(C(=O)Nc2cccnc2)C1 +CC(CNC(=O)C1CC(=O)N(Cc2ccccn2)C1)N1CCOCC1 +CCc1cc(NCc2noc(C(N)=O)n2)n2nccc2n1 +CC(C)C(=O)NCCNC(=O)C12CC3CC(CC(C3)C1)C2 +COc1ccccc1OCCC(=O)NCc1ccc2c(c1)OCO2 +CN1CC(C(=O)N(C)CCOc2ccc(F)cc2)CC1=O +COC(=O)N1CCC(NC(=O)c2nccnc2N)CC1 +Cc1nn(C)c2nc(-c3ccco3)cc(C(=O)NC3(C#N)CCCC3)c12 +O=C(NCc1nc2ccccc2n1Cc1ccccc1)c1cccnc1 +Cc1nccn1-c1cncc(N2CCC(C3(C)OCCO3)CC2)n1 +NC(=O)c1cc(-c2cc(O)cc(F)c2)ccc1Cl +COc1ccc(Cl)cc1NCCC(=O)Nc1cccc2cn[nH]c12 +COc1ccc(C(O)CNc2ccccc2C#N)cc1OC +O=C(Cn1c(-c2cscn2)nc2ccccc21)NCc1cccnc1 +O=C(Nc1cccc(-n2cnnc2)c1)C1CCCO1 +O=C(NCCc1ccccc1)Nc1cnn(-c2ccccc2F)c1 +Cc1csc(NC(=O)CCC(=O)c2ccc(C)s2)n1 +CCOCC1CN(S(=O)(=O)c2ccccc2C)Cc2ncn(C)c21 +COC(=O)C(CNC(=O)c1cc(C)oc1C)Cc1ccc(O)cc1 +Cc1cc2c(o1)c1cnn(CC(=O)N3CCOCC3)c(=O)c1n2C +COc1ccc(CNC(=O)C2CCCN2C(N)=O)cc1F +CC(C)NC(=O)c1ccc(OCC(=O)N2CCCC2)c(N)c1 +COCCN(C(=O)Cc1c(F)cccc1F)c1ccc(C#N)cc1 +CCN(Cc1cccc(NCc2nsc(N(C)C)n2)c1)C(C)=O +CCN(C(=O)Cn1cc(Br)ccc1=O)C1CCCCC1 +O=C(CNc1ccc(F)cc1)N1CCN(c2ccc(F)cc2)CC1 +Cc1nc2ccc(NC(=O)c3cccc(OCC(F)F)n3)cc2s1 +CCN1CC(C(=O)Nc2ccccc2C(=O)N(CC)CC)CC1=O +CC(=O)c1ccc(NC(=O)C2CSc3ncc(C)c(=O)n3C2)cc1 +CC(=O)Nc1cccc(-c2cccc3c(C(N)=O)cccc23)c1 +CC(=O)Nc1ccc(Cl)c(C(=O)N2CCC(n3ccnn3)CC2)c1 +C#CCOc1ccc(F)cc1NC(=O)c1ccnc(OC2CCC2)c1 +CC(C)c1csc(NC(=O)c2cc(N)cn2C)n1 +Cc1ccc(C)c(C(=O)N(C)C2CCN(C(=O)OC(C)(C)C)CC2)c1 +CN(Cc1cccnc1)C(=O)c1cc2ccccc2o1 +CSc1ccc(NC(=O)COC(=O)c2c(C)noc2N)cc1 +N#CC1(CCN2CCOCC2)Cn2c(cc3sccc32)C1=O +Cc1ccc(C)c(NC(=O)COC(=O)c2cccc(N)c2)c1 +O=C(Cn1ncc2c(=O)oc3ccccc3c21)NCc1cccs1 +Cc1cccc(OC(C)C(=O)Nc2ccc3c(c2)NC(=O)CO3)c1 +CC(=O)c1cccc(NCC(=O)NCc2cccs2)c1 +O=C(CCCc1ccccn1)N1CCN(c2cccc(O)c2)CC1 +CCNC(=O)CCCC(=O)N1CCCCCC1CC(C)C +CCc1onc(C)c1NC(=O)N1CCC(OC2CCCC2)CC1 +COc1cccc(SC(C)c2nc(N)nc(N(C)C)n2)c1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NC2CCc3ccccc32)[nH]n1 +CN(CC1CCCC1)S(=O)(=O)c1ccc(F)c(F)c1 +COc1ccc(CNC(=O)C2CC(=O)N(C3CCCCC3)C2)cc1 +COC(=O)c1cccc(NC(=O)c2ccc(C)cc2)c1 +COc1c(O)c(Cl)cc2c1C(C1CCCO1)NCC2 +COCC(C)n1c(C)cc(C(=O)CSc2nnc(C)s2)c1C +COC(=O)CC1CN(Cc2c[nH]nc2-c2cccnc2)CCO1 +COCc1ccccc1CNS(=O)(=O)c1ccc(C)c(Cl)c1 +Cc1cc(CNC(=O)c2c(-n3cccc3)sc3c2CCCC3)on1 +O=C(CC1CCCCC1)NCC1CN2CCCCC2CO1 +N#Cc1ccc(C(=O)NCc2ccnc(Oc3ccccc3)c2)cc1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)C1CCCc2ccccc21 +CCC1CCC(CNC(=O)CCCn2cncn2)CC1 +Nc1nonc1-c1nnc2c(n1)-c1ccccc1C2=O +Cc1cc(C)cc(NS(=O)(=O)c2ccc(-c3cc(C)n[nH]3)o2)c1 +Cc1cccc(OCCNC(=O)c2ccc(C(N)=O)cc2)c1 +O=C(CNC(=O)NC1CCC(C(F)(F)F)CC1)NCC1CC1 +CN(Cc1ccc(F)cc1)C(=O)CCc1ccccc1O +CCC(C)NC(=O)CCc1nnc(-c2ccoc2C)o1 +NC(=O)C1CCN(C(=O)NCc2ccnc(OC3CCCC3)c2)CC1 +CCCOc1cccc(NC(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +N#Cc1cc(O)cc(-c2cccc(S(=O)(=O)N3CCCC3)c2)c1 +CCOC(=O)C1CCN(C(=O)C2CN(C(C)=O)C2)CC1 +O=C(NCC1(N2CCOCC2)CCCCC1)c1cc(F)cc(F)c1 +CC1CN(C(=O)c2ccc(C(=O)NC(C)(C)C)cc2)CC(C)(C)O1 +CCn1ccnc(NC(C)CN2CCOCC2)c1=O +Cc1c(C(=O)NC2CCOc3ccccc32)cnn1-c1ccccc1 +COc1cccc(CNC(=O)c2cccc(OC(F)F)c2)c1 +CCCOc1nc(COC)nc(NC(C)C)c1N +Cc1cc(C)c(NC(=O)COc2ccccc2C(N)=O)c(C)c1 +CC1C(=O)N(CC(O)CO)c2cc(N)ccc2S1=O +O=C(COc1ccccc1)N1CCN(C2CCCC2)CC1 +N#Cc1ccc(-n2c(C3CC3)nc3ccc(F)c(F)c32)nc1 +CC(NS(=O)(=O)c1cccs1)C(=O)NCC1CC1C +Cn1cc(C(=O)Nc2cc(F)ccc2OCC2CCCO2)ccc1=O +CCOC(=O)CN(C(C)C)S(=O)(=O)c1cccc(F)c1 +COC(=O)c1sc(NC(=O)c2cccc(F)c2)nc1C1CC1 +Cc1cc(NC(=O)N2CCc3ccccc3C2)c[nH]c1=O +Cc1noc(COCC(=O)NC(c2ccc(Cl)cc2)C2CCC2)n1 +O=S(=O)(c1ccc(Br)c(Cl)c1)N1CCNCC1 +N#Cc1ccc(CN(CC(F)(F)F)C(=O)c2ccncc2F)cc1 +Cc1ccccc1C(=O)OC(C)C(=O)N1CCc2ccccc2C1 +Cc1cc(C(O)C(=O)Nc2ccccc2C(C)C)ccc1F +Cc1cccc(C(=O)OCCc2c(C)n[nH]c2C)c1C +COCC1CN(c2ccc(C#N)cc2F)CCO1 +CCNC(=O)CN(C)S(=O)(=O)c1ccc(OCC)c(Cl)c1 +COC(=O)c1ccc(C(=O)Nc2cnc(-c3ccccc3)nc2)nc1 +CC(C(=O)NC1CC1)S(=O)(=O)c1nc(-c2ccccc2)cs1 +COC1N=C(c2ccccc2)c2cc(Br)ccc2NC1=O +O=C(C1CCN(c2cncnc2N2CCCC2)CC1)N1CCCCC1 +CN(CC(=O)Nc1ccc(N2CCCC2)nc1)S(C)(=O)=O +Cc1csc(NC(=O)CN2CCOC(c3ccc(F)cc3)C2)n1 +CN(C(=O)c1ccccc1NC(=O)C1CC1)C1CCCCC1 +O=C(OCc1nc2ccccc2s1)C1CC2CCC1O2 +COCCN(Cc1ccco1)C(=O)CC(C)(C)C +Cn1cc(NC(=O)NCCCN2CCOCC2)cn1 +CCOc1cc(C#N)ccc1OCC(=O)NC(C)(C#N)C(C)C +CCOC(=O)c1ccc(-n2[nH]c(C(F)(F)F)cc2=O)cc1 +Nc1ccc2oc(=O)n(CCOc3ccc(F)cc3)c2c1 +O=C1CN(C(=O)c2ccc(OCc3cscn3)cc2)CCN1 +COc1ccc(Cc2nc(C#N)cs2)cc1OC +CN(Cc1ccccc1)C(=O)c1onc(-c2ccccc2)c1N +CNc1ccc(C2CN(C(=O)c3ccc(Cl)cc3)CCO2)nc1 +CC(CNC(=O)c1ccc(-n2ccnn2)cc1)CC1(C)OCCO1 +CC(=O)N(C)CC(=O)NC1CCc2c(F)cccc21 +O=C(COC(=O)c1ccoc1)Nc1ccc(Cl)cc1 +COc1ccc(-c2nc(C)no2)cc1-n1cnnn1 +CS(=O)(=O)c1cc(C(=O)Nc2ccccc2C#N)ccc1Cl +CCOc1ccc(C(O)c2ccc(OC)cc2)cc1 +Cn1cc(CNC(=O)CCC(=O)c2ccc3ccccc3c2)cn1 +NC(=O)C(NCC(F)(F)F)c1ccccc1Cl +COc1ccccc1OCC#CCN1CCOCC1 +N#Cc1cccc(C(=O)N(Cc2ccccc2)c2ccccn2)c1 +CC(C)Oc1ccc(CNS(=O)(=O)c2cccc(F)c2)cn1 +N#CCn1c(C(N)c2ccccc2)nc2ccc(F)c(F)c21 +Cc1noc(C)c1NC(=O)c1c(C)c2ccccc2oc1=O +CC1CCc2c(nc(N)n(CC(=O)NCC3CCCO3)c2=O)C1 +Cc1nnc(NCCCC(C)(C)C2OCCO2)c(C#N)c1C +Cc1ccc(N(C)C(=O)c2cc(C)nn2C)c(C)c1 +COc1ccccc1NC(=O)C1(C)Oc2cccnc2N(C)C1=O +Cc1cc2nnc(S(=O)(=O)CC3CCOC3)n2c(C)n1 +Cc1cc(C)nc(N(C)C2CCc3ccccc32)n1 +CCNC(=O)N1CCN(C(=O)c2ccc(C)s2)CC1 +CC(NC(=O)CC(C)(C)C)c1nc(-c2ccccn2)no1 +Cc1nc(NC(=O)c2cccnc2N2CCOCC2)sc1C +COc1ccc(CNC(=O)c2cn3cc(Cl)ccc3n2)c(OC)c1 +CC(=O)c1cccc(S(=O)(=O)NCc2nc(C)no2)c1 +Cc1cccc(CCCOC(=O)c2ccccc2C)n1 +CC(=O)NC(CC(=O)NCC(F)(F)F)c1ccccc1 +Cc1ccc(NC(=O)Cn2ccccc2=O)cc1Cl +CC(C)C(CNC(=O)NCc1nnc2ccccn12)N1CCOCC1 +NC(=O)c1cccc(CS(=O)(=O)c2ccc3ccccc3n2)c1 +CN(C(=O)COc1ccccc1)C(C#N)c1ccco1 +Cc1cc(NC(=O)NCCN2CCN(C(=O)C3CCC3)CC2)n(C)n1 +NC(=O)C1(CNC(=O)Cc2cnn(-c3ccccc3)c2)CCOCC1 +COc1cccc(OCC(=O)NCC#Cc2ccccc2F)c1 +CSc1ccc(C(=O)Nc2nnc(-c3csc(C)n3)o2)cc1 +Cc1cc(C)c(NCCNc2c(C)cccc2C)c(C)c1 +COc1cc(C(=O)Nc2c(C)n[nH]c2C)cc(Cl)c1OC +COC(=O)CNC(=O)CCn1nc(C)c(Br)c1C +CCN(C(=O)c1scnc1C1CC1)c1ccncc1 +CCN(C(=O)c1cccn(Cc2cccc(C)c2)c1=O)C1CC1 +CC(Cc1ccc(F)cc1)NCc1cncs1 +Cc1csc(NC(=O)NCc2cn3cc(Cl)ccc3n2)n1 +Cc1ccc(OC(=O)Cn2nc(C)c3ccccc3c2=O)cc1 +Cc1ncsc1-c1nc2ccccc2n1Cc1nc(C2CC2)no1 +Cc1nnc(-c2ccc(NC(=O)N(C)CCC#N)cc2)o1 +CCN1CC2(CCC1=O)CCN(C(=O)CCc1ccccc1F)CC2 +Cc1nnc(Sc2ccc(NC(=O)Cc3ccc[nH]3)c(C)c2)s1 +CC(CS(=O)(=O)N1CCn2c(nn(C)c2=O)C1)c1ccccc1 +Cc1nc(C)c(C(=O)N(C)Cc2ccc3c(c2)OCCO3)s1 +CC(Nc1cc2[nH]c(=O)[nH]c2cc1Br)c1cccs1 +CC(C)(C(=O)N1CCNC(=O)CC1)c1ccc(Br)cc1 +O=C(Cc1cccs1)Nc1ccc2c(c1)CCC(=O)N2 +Cn1ncnc1SCCCc1nc2ccccc2o1 +CNS(=O)(=O)Cc1ccc(CNC(=O)N2CCCC2)cc1 +CN(CCc1nc(-c2cccc(N)c2)cs1)Cc1ccccc1 +O=C(c1ccnc(-n2cncn2)c1)N(Cc1cccs1)C1CC1 +Cc1cc(C)nc(NC(=O)c2c(C(N)=O)noc2C)c1 +COc1cc2ncn(Cc3nccn3C)c2cc1OC +O=C(CS(=O)(=O)c1ccc(Br)cc1)N1CCCC1 +Cc1ccc2[nH]c(C(=O)N3CCCC(N4CCNC4=O)C3)cc2c1 +CN(CCC#N)S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CCOc1cccc2n[nH]c(=NC(=O)Nc3cccc(C)c3)n12 +CCNC(=O)N1CCN(CC(=O)N(C)C2CCC(C)CC2)CC1 +Cc1n[nH]c(SCc2ccc(NC(=O)c3cccnc3)cc2)n1 +N#Cc1cc(NCCCOCC(F)(F)F)ccc1F +Cc1cccc(CNS(=O)(=O)c2ccccc2C#N)n1 +CC(C)Oc1cc(NCc2nnc3n2CCCCC3)nc(N)n1 +O=S(=O)(NCCOc1ccccc1)c1c(F)cccc1F +Cc1cc(=O)n(CC(=O)NCc2ccco2)c(-c2ccccc2)n1 +Cc1cc(C)cc(N2CCC(C(=O)NC(C)C(N)=O)C2=O)c1 +Nc1cccc(-c2ccc3nnc(-c4cccs4)n3n2)c1 +CC(CO)NC(=O)c1ccc(COc2ccccc2)cc1 +O=C(CSc1nnc(NC2CC2)s1)c1ccc2c(c1)OCCO2 +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccoc1 +Cc1ccc(CN(C)S(=O)(=O)c2cnc3onc(C)c3c2)s1 +CCOc1ccc(S(=O)(=O)NC(C)C)cc1C(C)C +COc1ccc(C(=O)NCC(C)c2nc(-c3ccccc3)no2)nn1 +Cc1cc(F)ccc1NC(=O)CCc1c(C)nn(C)c1C +COc1ccc(CO)cc1-c1ccc2c(c1)OCCO2 +O=C(CCC(=O)N1CCCCC1)NC12CC3CC(CC(C3)C1)C2 +COc1cccc2cc(C(=O)NCC3(CO)CC3)c(=O)oc12 +COc1ccc(N(C(C)C(=O)NC(C)(C)C)S(C)(=O)=O)cc1 +O=S(=O)(Cc1ccon1)N1CCN(CCCc2ccccc2)CC1 +COc1cc(C2NCCc3cc(F)c(F)cc32)ccc1O +CC(NC(=O)Cc1ccc[nH]1)c1ccccc1Cl +Cc1ccc(NC(=O)c2ccc(-n3cnnc3)cc2Cl)cc1C +CCC(=O)N1CCCN(C(=O)c2cccc(-c3n[nH]c(C)n3)c2)CC1 +C#CCNC(=O)c1ccccc1NCc1noc(C)n1 +O=C(COC(=O)c1cnc(C2CCCO2)s1)Nc1ccccc1 +N#Cc1ccsc1NC(=O)CSc1ncnc2sccc12 +CC(=O)NC(CC(=O)N(C)Cc1cccc(F)c1)c1ccc(C)cc1 +Cc1nc(-c2cccc(NC(=O)CSc3nncs3)c2)n[nH]1 +CCc1nnc2sc(COc3ccc(C)cc3)nn12 +Cc1ccc2c(c1C)CCNC2CNC(=O)OC(C)(C)C +N#Cc1ccc2ncc(CN3CCC(Oc4ccccc4)CC3)n2c1 +COC(=O)c1ccc(NC(=O)CNC(=O)c2cc(C)cc(C)c2)cc1 +CC(=O)NCCC(=O)Nc1cc(C)nn1Cc1cccc(C)c1 +Cn1c(=O)ccn(CC(=O)Oc2c(Cl)cccc2Cl)c1=O +COc1ccc(C(=O)CSc2cccc3cccnc23)cc1OC +COC(=O)c1sccc1NC(=O)Cc1cc(C)ccc1C +Cc1csc(C2CCN(C(=O)c3c[nH]c4cccc(F)c34)CC2)n1 +O=C(Cc1ccc(-n2cccc2)cc1)N1CCCC1c1ccncc1 +O=C(C1CCC(F)(F)CC1)N1CCCCC1c1cc[nH]n1 +COC(=O)CN(C(=O)c1cc(C(C)=O)c[nH]1)C(C)C +CCOc1ccccc1CNS(=O)(=O)c1ccc(Cl)cc1 +Cc1cc(N)ccc1S(=O)(=O)NCCc1cccs1 +COc1ccc(C(=O)NC(Cc2ncc[nH]2)c2ccccc2)cc1 +c1ccc2c(c1)ccc1nnc(SCCN3CCOCC3)n12 +CCCC(=O)c1ccc2c(c1)N(COC)C(=O)C(C(C)C)O2 +CCN(C(=O)COc1ccc(C(N)=O)cc1)C(C)c1ccc(F)cc1 +CN(C)C(=O)C(Sc1n[nH]c(N)n1)c1ccccc1 +CCc1nnc2n1CCN(CC(=O)Nc1nnc(C)s1)C2 +CCc1cnc(CN(C(C)=O)C2CCN(C3CCOC3=O)C2)o1 +COc1cccc(C(=O)N(C)Cc2nc3ccccc3s2)c1O +COc1cc(C)c(NC(=O)Cc2csc(C)n2)cc1OC +Cc1occc1-c1nnc(CCC(=O)NCCc2ccc(F)cc2)o1 +CCCCOc1nc(C)cc(COC)c1C(N)=O +COc1cc(Cn2ccnc2-c2nccn2C)cc(OC)c1OC +CCOC(=O)C1=C(C)OC(N)=C(C(=O)OCC)C1c1ccc(C)o1 +O=C(CCN1C(=O)CCc2ccccc21)Nc1ccc2[nH]ncc2c1 +CCCC1CN(C(=O)Nc2ccc(C)c(C(N)=O)c2)CCO1 +Cc1cc(C)n2nc(C(=O)Nc3ccccc3N(C)C)nc2n1 +CC1CCN(S(=O)(=O)N2Cc3ccccc3CC2C(N)=O)CC1 +COCCC1(CNC(=O)Nc2cc(F)c(F)cc2Cl)CC1 +Cn1c(SCC(=O)N(CCC#N)c2ccccc2)nnc1C1CC1 +O=C(NCCc1cscn1)c1c[nH]c(=O)c(Br)c1 +Cc1ccc(C(=O)N(CCc2ccccc2)Cc2ccncc2)c(=O)[nH]1 +CC(=O)Nc1cc(F)c(S(=O)(=O)Nc2c(C)n[nH]c2C)c(F)c1 +COCCNC(C)(C(=O)OC)c1ccc(Cl)cc1Cl +Cc1cc(Br)ccc1C(=O)NC1CCCNC1=O +Cc1ccc2c(c1)cc1c(=O)n(CC(=O)N3CCCC3)nc(C)n12 +Cc1cc(NC(C)Cc2ccc(F)cc2)n2ncnc2n1 +CCCNS(=O)(=O)c1ccc(C)cc1SCC +O=C(Nc1ccc(-n2cncn2)cc1)C1CC=CCC1 +Cc1csc(S(=O)Cc2cccc(Br)c2C)n1 +O=C(CCCc1cccs1)NC1CCOc2ccccc21 +Cc1cccc(C2CC2C(=O)N(C)S(=O)(=O)c2c(C)noc2C)c1 +CCCS(=O)(=O)N1CC=C(c2ccccc2Cl)CC1 +O=C(CNc1ccc(F)cc1Cl)N1CCN(c2ccccc2)CC1 +COc1ccccc1OCC(=O)N1CCN(CCC#N)CC1 +Cc1nc2nc(N)nn2c(C)c1CC(=O)Nc1nccs1 +CN1CCN(S(=O)(=O)c2cccc(F)c2C#N)CC1 +O=C(Cn1cnc(-c2ccccc2)cc1=O)NCc1ccncc1 +CCS(=O)(=O)NCCc1csc(-c2ccc(Cl)cc2)n1 +CC(=O)c1csc(NC(=O)c2cccc(F)c2F)n1 +CC(C)(C(=O)Nc1cccc(F)c1F)c1cccnc1 +N#Cc1ccc(NC(=O)CNc2ccccc2)cc1Cl +CC(Sc1ccc(-n2ccnc2)nn1)c1ccccc1 +CSc1ccc(C(=O)NC(C)c2c(C)noc2C)cn1 +CN(C(=O)COC(=O)CNC(=O)C1CCCCC1)c1ccccc1 +CCn1nnnc1NCc1cc(Br)ccc1OC +COc1ccc(OC)c(-c2c(C3CC3)noc2N)c1 +CN(C)C(=O)COc1cccc(C(=O)Nc2cccn(C)c2=O)c1 +COC(=O)c1cc(-c2cc(N)c(OC)c(OC)c2)nn1C +COc1ccc(C(=O)NC2CCN(c3nccs3)CC2)cc1OC +Cc1ccc(CC(=O)N2CCN(Cc3cc(C#N)cs3)CC2)cc1 +CC(NC(=O)CSc1cccc(C(F)(F)F)c1)C1CCCO1 +CCN(CC)C(=O)CSc1nnc(Cc2ccccc2F)o1 +Cc1ccccc1C(=O)OC(C)CN1CCOCC1 +O=C1COc2ccc(C3=Nc4ncnn4C(c4ccccc4)C3)cc2N1 +O=C(c1ccccc1)N1CCN2C(=O)N(Cc3ccccn3)CC2C1 +FC(F)Sc1nnc(NCc2ccccc2)s1 +CNc1nc(NCc2cccnc2)nc(NCc2cccnc2)n1 +Cc1nnc(CN(C)C2Cc3ccccc3C2)n1C +COc1ccc(CCNC(=O)c2cccc3nc(C)oc23)cc1OC +CCOC(=O)C1CCN(C(C(=O)NC2CC2)c2ccc(F)cc2)CC1 +O=C(CSc1ncc2ccccn12)c1cc(F)ccc1F +CCN1CCN(C(=O)Cc2ccc(OC)c(OC)c2)CC1 +Cc1cc(NC(=O)CNc2ccc(C(=O)N3CCCC3)cc2)on1 +COCCNC(=O)Cc1ccc(NC(=O)c2ccc(C)c(C)c2)cc1 +Cc1cccc(OCCC(=O)Nc2nnc(C(F)(F)F)s2)c1C +CC1CC1c1nc(C(C)(C)NC(=O)c2cccc(Cl)c2)no1 +CC(C)OC(=O)c1ccn(Cc2cccc3cccnc23)c(=O)c1 +N#Cc1ccc(Cl)c(NCC(=O)Nc2ccnn2C2CCCC2)c1 +Cc1cc(NC(=O)C(C)OC(=O)C2Cc3ccccc3O2)no1 +CC(C)(C)OC(=O)Nc1ccc(F)cc1NC(=O)c1ccnnc1 +N#Cc1cnn(-c2ccc(C(=O)NC3CCc4ccccc43)cc2)c1N +CCc1ccccc1Nc1ncnc(NC(C)C)c1N +O=C(c1ccco1)N1CCN(CCn2cccn2)CC1 +Cc1cccc(C)c1NC(=O)NC(C)c1nnc2ccccn12 +O=C(Cc1ccccc1Cl)Nc1cc(F)ccc1O +COCC(=O)N1CCCN(Cc2ccc(C#N)cc2)CC1 +Cc1ccn2c(=NC(=O)CCc3nc4c(F)cccc4[nH]3)[nH]nc2c1 +CS(=O)(=O)NCCCSc1nc(-c2cccs2)n[nH]1 +CCCCOc1ccccc1NC(=O)c1cc(C(N)=O)cs1 +CC(NC(=O)C1CC(=O)N(C2CC2)C1)C12CC3CC(CC(C3)C1)C2 +Cc1nc(C(C)(C)C)sc1C(=O)N(C)CC(=O)NC(C)(C)C +Cc1ccccc1CN(C)C(C(=O)NC1CC1)c1ccccc1 +O=C(NCc1cc(-c2cccs2)on1)c1ccc2c(c1)OCO2 +Cc1ccc(CNC(=O)Cn2c(C)cc(C)c(C#N)c2=O)cc1 +CC(=O)c1ccc(NC(=O)Nc2cn(C)c(=O)c3ccccc23)cc1 +CC(C)CN(C(=O)CSc1nnnn1C(C)(C)C)C1CC1 +CN(CCc1ccccc1)C(=O)NCC1CN2CCCCC2CO1 +CCCn1cc(CNC(=O)c2cc(CC(C)C)no2)cn1 +CC(C)(C)n1nc(C2CCOCC2)nc1C1CC=CC1 +CC1(C)CCC(CNC(=O)c2n[nH]c(=O)c3ccccc23)CC1 +Cc1ccc(-c2nc(CC(=O)Nc3nc(C4CC4)cs3)cs2)o1 +CCC1=C(C(=O)OC)C(c2ccc(OC)c(OC)c2)NC(=O)N1CC +Cc1cccc(CNC(=O)c2c[nH]c3ccccc23)c1 +Nc1ccc(-c2nc(-c3c(F)cccc3F)no2)cc1 +CCC1CCCN(S(=O)(=O)c2ccc(C(C)=O)cc2)C1 +Cc1cc2nc(-c3ccccc3)c(=O)[nH]c2cc1C +COC(=O)C1CC(=O)N(c2ccc(Br)cc2)C1 +CNS(=O)(=O)c1ccc(NC(=O)C(C)Oc2cccc(C)c2)cc1 +Cc1ncc(CNc2ccc(F)c(C(N)=O)c2)s1 +O=C(CCSc1nnc(-c2ccc(O)cc2)o1)N1CCOCC1 +O=C(NCc1cccnc1)Nc1ccn(Cc2ccccc2)n1 +CCC1C(=O)NCCN1Cc1cc(-c2ccc(Cl)cc2)no1 +O=C(CN1CCCCC1=O)NC(c1ccccc1)c1ccccc1 +Cc1ccc(N2CC(C(=O)OCCNc3cccnn3)CC2=O)cc1 +CNC(=O)Cc1ccc(CC2COc3c(cccc3OC)C2)cc1 +Cc1ccc(C(=O)OCC(=O)N2CCCCCC2)c(O)c1 +CC1(C(=O)N2CCOCC2)CN(Cc2cccs2)CCO1 +COc1ccccc1OCc1ccc(C(=O)NCC2CCCO2)cc1 +COc1cccc(OCC(=O)N2CCC(C(N)=O)C2)c1 +CCN(CC)c1ccc(C(=O)NC2(C#N)CCOCC2)cc1 +Cc1nc(C)n(C2CCCN(C(=O)c3c(F)cc(F)cc3F)C2)n1 +OC1CCN(Cc2ccncc2)C1Cc1ccccc1 +Cc1ccc(NC(=O)N2CCCCC2c2nc[nH]n2)cc1Cl +CC(C)CNC(=O)NCC1(C(N)=O)CCOCC1 +Cc1ccc(OCC(=O)Nc2ccnn2C2CCCC2)cn1 +CC(C)(C)c1ccccc1NC(=O)COC(=O)c1cccnc1N +Cc1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)cc1C +CNC(=O)CC(c1ccc(OC)c(OC)c1)C1CC1 +CN(C)C(=O)CN(C)C(=O)C1CCCOC1c1ccccc1 +CC(C#N)CNC(=O)c1cccc(COc2ccc(C#N)cc2)c1 +Cc1nn(-c2cccc(Cl)c2)nc1C(=O)N(C)CC(O)C1CC1 +O=C(CCN1C(=O)CCc2ccccc21)OCc1nc2ccccc2[nH]1 +CC(CNC(=O)C1CC(=O)N(C)C1)c1nc(-c2ccccc2)no1 +CC(C)CCC(=O)N1CCN(CCc2ccccn2)CC1 +Cc1ccc(SCCNC(=O)c2ccoc2)cc1 +CN1C(=O)C2CCC1CN(C(=O)Nc1cccc3ccccc13)C2 +CC(C)NC(=O)COc1ccc2ccc(O)cc2c1 +O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1ccc(Cl)cc1 +O=C(Nc1n[nH]c(C2CCCCC2)n1)C1CCCCC1 +Cn1cc(CCO)c2cc(Br)ccc21 +CC(C)c1ccc(OCC(=O)NC2CC(=O)N(C3CC3)C2)cc1 +CCC(C)C(=O)Nc1cccc(OCc2ccccn2)c1 +CC(CC#N)N1CCN(C(=O)c2ccc(F)cc2)CC1 +COc1ccc(C(=O)N2CCCCC2CC(C)C)cc1-n1cnnn1 +CCOC(=O)NCCC(=O)NC1CCCN(c2ncccn2)C1 +C=C(C)CN(CC)C(=O)NCc1ccc(OC(C)C)nc1 +CS(=O)(=O)NCC(=O)NCCSc1ccc(Cl)cc1 +CC(NC(=O)CN(C)c1ccc(F)cc1)C(=O)N(C)C +CCc1noc(C)c1C(=O)NC(C)Cc1cccs1 +O=C(Cn1nnc(-c2ccsc2)n1)NCc1ccccc1 +CC(=O)N1CCC(c2nc3ccc(C(F)(F)F)cc3[nH]2)C1 +Cc1cccc(-c2cc3[nH]c(C)c(CCO)c(=O)n3n2)c1 +Nc1cc(Br)cc(Cl)c1N1CCOCC1 +O=C(Nc1ccccc1N1CCOCC1)c1ccc(=O)[nH]c1 +CC(OC(=O)C1CC1c1ccccc1)c1ccccn1 +COc1ccc(C(=O)Nc2ccc(C)cn2)cc1Br +COCCN(CC1(C)CCOCC1)S(=O)(=O)c1ccccc1 +O=C(Cc1nnc(-c2ccncc2)o1)NC1CCCC1 +CN(c1ccccc1)S(=O)(=O)c1ccc(C(=O)OCC(N)=O)cc1 +N#Cc1csc(CNc2cnn(-c3ccccc3)c2)c1 +COc1ccc(Nc2c3c(nc4ncnn24)CCC3)cc1 +CCn1nc(C(=O)Nc2ccc(C(C)=O)c(C)c2)ccc1=O +Cc1c(CNS(=O)(=O)c2ccc3c(c2)C(C)(C)C(=O)N3)cnn1C +Cc1ccc(F)cc1S(=O)(=O)Nc1ccc(CC(N)=O)cc1 +C=CCNC(=O)C1CC(=O)N(c2ccc(O)cc2)C1 +COc1c(F)cc(NC(=O)Cc2c[nH]c3ccccc23)cc1F +CCCN(CC1CC1)C(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +CC(=O)Nc1ccc(Cl)cc1NCC(=O)NC1(C#N)CCCC1 +Cc1cc(NCc2c[nH]nc2-c2ccccc2)no1 +COc1cc(CN2CCN(c3cccs3)CC2)cc2c1OCCO2 +CC1COCCN1C(=O)Cc1csc(-c2cccc(F)c2)n1 +O=C(NCCCC1Nc2ccccc2S1)c1ccc2[nH]nnc2c1 +NC(=O)CSc1nnc2c(n1)[nH]c1ccc(F)cc12 +COCC(C)NC(=O)Nc1ccc(-c2nc(C(C)C)no2)cc1 +CN(C)c1ncc(CNc2cccc(N3CCCC3=O)c2)cn1 +c1cc(-c2nc(CSc3nnnn3C3CC3)cs2)cs1 +Cc1ccc(S(=O)(=O)CC(=O)N2CCCC3CCCCC32)cc1 +COc1ccc(NC(C)C(=O)Nc2c(C)cccc2C(C)C)cn1 +Cc1cccc(NC(=O)c2ccc(F)c(S(=O)(=O)N3CCC3)c2)n1 +COc1ccc(C2(CNC(=O)c3cnccn3)CCOCC2)cc1 +O=c1c(NS(=O)(=O)Cc2ccccc2)cnc2ccccn12 +CC(C)C(NC(=O)CCn1ccccc1=O)c1ccccc1 +Cc1c(F)cccc1-c1ccc(CN2CCOC(C(N)=O)C2)o1 +CCCN(C)C(=O)CCc1cc2ccccc2[nH]c1=O +Cn1ccc(Cn2cc(C(F)(F)F)cc(Cl)c2=O)cc1=O +CCCCOC(=O)C1CCN(C(=O)N(C)C)CC1 +Cc1cnc(C(=O)NC2CC(=O)N(CCc3ccccc3)C2)cn1 +COCc1cncc2c1CCN(C(=O)c1ccccn1)C2 +COc1ccccc1C(=O)N1CCC(CNC(=O)OC(C)(C)C)CC1 +COC(=O)c1ccc(NCc2nc(C)cs2)c(F)c1 +COCC(C)(C#N)NC(=O)c1cc(N2CCCC2=O)ccc1Cl +CCC1CCCCCN1C(=O)c1ccc2c(c1)NC(=O)CO2 +O=C(CCc1ccc2c(c1)OCO2)NCCCO +CCn1c(SCC(=O)NC2CC2)nnc1-c1ccccn1 +NC(=O)Cn1ccnc1Cc1ccc(C(F)(F)F)cc1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(OC)c(O)c1 +Cc1cc2c(cc1C)N(CC(=O)NC1CCCC1)C(=O)CN2 +c1cn(C2CC2)c(SCc2nnnn2C2CC2)n1 +Cc1cc(C(F)(F)F)nn1Cc1nc2c3cnn(C)c3ncn2n1 +O=C(Nc1ccc(OCC2CCOCC2)cc1)N1CCC(CO)CC1 +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1cc(Cl)ccc1F +NC(=O)c1cccc(CNC(=O)Nc2ccccn2)c1 +C#Cc1cccc(NC(=O)C(C)c2c(C)noc2C)c1 +COC(=O)c1cc(Cl)ccc1OCC(=O)NCc1ccccc1 +CCN(CC)C(=O)CN1CC(C)(C)Oc2ccc(N)cc21 +CC(Cc1cnccn1)N(C)Cc1cnc(N2CCCC2)nc1 +CC(C)(C)C(O)CN1CCN(C(=O)C2CC2c2cccnc2)CC1 +COc1ccc(C(=O)NC(C)c2ccc(C)cc2)cc1OC +O=C(NCc1cccnc1)c1ccc(NC(=O)c2ccco2)cc1 +COCCN(Cc1ccc(C)cc1)C(=O)c1c(C)nc2ncccn12 +CC(Oc1ccc(C(=O)c2ccc(Cl)cc2)cc1)C(N)=O +NC(=O)c1c(NC(=O)C#Cc2ccccc2)sc2c1CCC2 +CCCCn1nnnc1NC(=O)NCc1c(C)cc(C)nc1OC +CN(C)C(=O)N1CCC(C(=O)Oc2ccccc2OC(F)F)CC1 +COc1cc(OC)cc(C(=O)N2CC=C(c3ccc(C)cc3)CC2)c1 +COc1cc(-c2nc(C)c(C)o2)cc(OC)c1OC +O=C(CCC(=O)c1ccccc1)OCC1CC=CCC1 +O=S(=O)(Nc1cnc(-c2ccccc2)nc1)c1ccc(F)c(F)c1 +CCOC(=O)CNC(=O)C1CC(=O)N(C2CCCC2)C1 +CC1C(=O)N2CCCc3cc(S(=O)(=O)N4CCCCCC4)cc1c32 +CC(NC(=O)C(C)(C)C)C(=O)OCc1cc(C#N)ccc1F +CCN(C)C(=O)c1ccc(OC)c(C#CCCO)c1 +Cc1cccc2c(NCCO)ncc(Br)c12 +O=S(=O)(Cc1ccccc1)NCC1(CCO)CCCCC1 +N#Cc1ccc(C(c2ccc(C#N)cc2)n2cncn2)cc1 +O=c1[nH]c(C2CCCC2)nc2c1Cc1ccccc1OC2 +CCCNc1nc2c([nH]c1=O)c(=O)n(C)c(=O)n2C +Cc1noc(C2CN(C(=O)c3ccncc3)CC2C)n1 +CCC(C)(C)c1ccc(OC(=O)C(C)NC(C)=O)cc1 +CCc1cccc(C)c1NC(=O)N1CCCC(CN2CCOCC2)C1 +Nc1cccc(OCCNc2cccc(Cl)c2)c1 +CC(c1c(F)cccc1F)N1CCN(C(=O)c2cccc(F)c2)CC1 +Cn1cc(C(=O)NCC(C)(C)c2ccccc2F)cn1 +CC1CCN(C(=O)c2csc(-c3cnccn3)n2)c2ccccc21 +Cc1ccc(-n2nnc(C#N)c2C(F)(F)F)cc1 +Cc1ccc(OC2CCN(C(=O)Nc3ccc(F)cc3)CC2)cn1 +CC1CN(C(=O)c2ccc(OCC(F)F)nc2)C(C)CO1 +CCCc1c2c(nc3cc(C(N)=O)n(C)c13)CC(C)(C)CC2=O +COc1ccc(CC(=O)NCCOc2cccc(C)c2)cc1F +CCC(C)n1nccc1NC(=O)CCC(=O)c1cccs1 +Cc1c(C(C)NC(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)cnn1C +CCc1sc(C(=O)NCC(=O)Nc2nccs2)cc1C +CC(C)Cc1nnc2sc(NC(=O)c3cccs3)nn12 +O=C(Cn1cnnn1)NCCOc1ccccc1-c1ccccc1 +NC(=O)c1ccc(NC(=O)c2ccc(F)c(F)c2F)cc1 +NC(=O)c1ccc(NC(=O)C2CC(=O)Nc3cc(F)ccc32)cc1 +COc1ccc(C2CN(c3nccc(C)n3)CC2NC(C)=O)cc1 +CC(NC(=O)c1cccc(OCC(F)F)n1)C(C)(C)C +CCC(Sc1nnc(-c2ccccc2OC)n1N)C(N)=O +C=CCNC(=O)c1ccc(NS(=O)(=O)c2ccc(C)c(C)c2)cc1 +C=CCc1cc(C(=O)NC(C)c2ccncc2)cc(OC)c1OC +Cn1cnc2cc(-c3noc(-c4ccccc4F)n3)ccc21 +Cn1c(C(F)(F)F)nn(Cc2cccc(C(F)(F)F)c2)c1=O +COC(=O)c1ccc(C(=O)NC2(C#N)CCCC2)cc1 +O=C(COc1ccccc1O)Nc1ccccc1OCC(F)(F)F +Cc1ccc(NC(=O)N2CCCN(C(N)=O)CC2)s1 +COC(=O)C1CCN(C(=O)Cn2ccc(-c3ccsc3)n2)CC1 +CCOc1ccccc1NC(=O)CN1C(=O)COc2ccc(C)cc21 +CC(C)(C)NC(=O)c1ccccc1NC(=O)C1CCC1 +O=C(N1CCN(c2ncccn2)CC1)C1(c2ccccc2)CC1 +O=C1CCSc2ccc(C(=O)NCCc3cccnc3)cc2N1 +COc1ccnc(NC(=O)CCc2nc3ccccc3s2)c1 +CC(C)(C)CCNC(=O)C1CCN(S(N)(=O)=O)CC1 +Cc1ccc(F)cc1C(=O)NC1CCCN(Cc2ccccc2)C1=O +CSc1c(Cl)cccc1NC(=O)N1CCCC(O)C1 +Cc1nn(C)c(N(C)C)c1CNCCc1cnn(C)c1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3nccs3)nn2)n1 +Cc1cn2c(nc3c2c(=O)n(CC=Cc2ccccc2)c(=O)n3C)[nH]1 +COc1cc(OC)cc(-c2nc(-c3ccc(OC)c(OC)c3)no2)c1 +CC(CC#N)N(C)C(=O)Nc1ccc(C#N)c(Cl)c1 +CNC(=O)c1cnn(-c2cccc(F)c2)c1-n1cccc1 +CC(CC(=O)N1CCNCC1)Oc1ccccc1C(C)(C)C +Cc1ccc(NC(=O)NC2CCCN(C(=O)OC(C)(C)C)C2)s1 +CCCCS(=O)(=O)N1CCCC1C(=O)N1CCN(C)CC1 +Cc1cc(C)n(Cc2cccc(OC(F)F)c2)n1 +CC(NCC(F)(F)F)(C(N)=O)c1ccc(F)c(Cl)c1 +CS(=O)(=O)NCc1ccc(NC(=O)C2CC3CCC2C3)cc1 +CCCN(C)C(=O)c1ccc(S(=O)(=O)NC2CC2)cc1 +c1cnc(NCc2ccc(-n3ccnc3)nc2)nc1 +CC(=O)c1ccc(Nc2ncc(Br)cc2N)cc1 +CCOc1ccnc(N2CCN(C(=O)c3occc3C)CC2)n1 +Cc1cccc(NC(=O)CN(C)C(=O)c2ccc3[nH]nnc3c2)c1C +CCOC(=O)C1=C(C)C(C(=O)N(C)Cc2ccccc2)C(C)=N1 +Cc1cc(C)c2c(N(C)C)nc(C(=O)NCc3cccnc3)nc2n1 +COc1ccccc1CNC(=O)COc1ccc(F)c(F)c1 +CC(=O)Nc1ccc(OC(=O)CC2CCCC2)cc1 +O=C(OCCOc1ccccc1)c1cc(Cl)c[nH]1 +CCC(C)c1cc(C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)on1 +Cc1nc(-c2ccco2)ccc1C(=O)N(C)CC1CC1 +COc1ccc(NC(=O)n2nc(C)c3ccccc32)c(OC)c1 +Cc1cc(NC(=O)CCNS(=O)(=O)c2ccc(F)cc2)no1 +CCOc1ncccc1C(=O)Oc1ccc2c(c1)OCO2 +CCC1C(=O)NCCN1C(=O)Cc1cccc(C)c1 +Cc1ccc(N2CCCC(Nc3nccc(C(F)(F)F)n3)C2)nn1 +O=C(NCCC(O)c1cc2ccccc2o1)Nc1cccs1 +COc1ccc(Cl)cc1C(=O)NCc1ccc(NC(C)=O)cc1 +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1ccc2cc[nH]c2c1 +CNC(=O)c1sccc1S(=O)(=O)NC1CCCCC1 +COc1ccc(C(=O)N(C)c2ccccc2)c(OC)c1OC +Cc1nn(CC(=O)NCc2cccs2)c(=O)c2cccn12 +CC(C)(C)C(=O)Nc1cc2c(cc1N)OCCO2 +Cc1csc(NC(=O)Cn2nnn(-c3cccs3)c2=O)n1 +Cn1cnn(CC(=O)NCC(O)c2ccccc2F)c1=O +COc1ccccc1-c1noc2ncnc(NC(C)C)c12 +CC(C)Oc1ccc(C(=O)C2CCCCN2)cc1F +CCC1CCCCN1C(=O)C(C)Nc1ccc(NC(C)=O)c(OC)c1 +COCc1cc(N2CCC(=O)CC2)nc(-c2cnccn2)n1 +N#Cc1cc(C2CCCC2)nc(N)c1Br +CCCNC(=O)CN(CC)S(=O)(=O)c1ccc(C)cc1 +CCOc1cc(C)c(Cc2c(O)n[nH]c2N)cc1C +Nc1ccc2c(c1)N(C(=O)CCc1ccccc1)CCS2 +CC(=O)Nc1ccc(NC(=O)Cn2nnc(C(C)=O)c2C)cc1 +CC(NCC(c1ccccc1)N1CCOCC1)c1ccncc1 +Cc1ccc(C(=O)NCC(=O)OCc2cccc(C#N)c2)cc1C +Cc1nc(-c2c[nH]c(C(=O)N(C)CC(=O)NC(C)C)c2)cs1 +CS(=O)(=O)N(CC(=O)N1CCC(C(N)=O)CC1)C1CCCCC1 +CN(Cc1ccc(C#N)cc1)CC(O)c1ccc(F)c(F)c1 +CC(=O)Nc1ccc(SCCC(=O)Nc2ccccc2C#N)cc1 +N#Cc1ccc(C(=O)N2CCC3(CC(=O)c4ccccc4O3)C2)cc1 +CSc1nnnn1-c1c(C)n(C)n(-c2ccccc2)c1=O +Cc1ccc(C(=O)N(C)C)cc1NC(=O)Cc1ccc(F)cc1F +CC(C)Nc1cccc(CNC(=O)N2CCC3(CC2)OCCO3)c1 +CNS(=O)(=O)c1cccc(CNC(=O)CCn2cc(C)cn2)c1 +Cn1cccc1CN1CCN(Cc2ccc(Cl)cn2)CC1 +CC(C)c1ccc(S(=O)(=O)Cc2noc(C3CC3)n2)cc1 +CC(C)(C)c1nnc(SCC(=O)NCc2cccs2)n1N +COc1ccc(NC(=O)COc2ccc(C)c(C)c2)cc1OC +CCCc1cnc(C)nc1N1CCN(Cc2ccccc2)CC1 +COC1C(O)C(CO)OC1n1cnc2c(=O)[nH]cnc21 +CCS(=O)(=O)c1ccccc1C(=O)Nc1ccc2scnc2c1 +CC(=O)N(CCc1ccccc1)CC(=O)NCc1scnc1C +O=C(COC(=O)CC1CC2CCC1C2)NC1CC1 +O=C(Cc1csc(-c2ccco2)n1)N(CC1CCOC1)C1CC1 +O=C(Cc1csc(-c2ccccn2)n1)Nc1ccccn1 +Cc1nc2ccc(NC(=O)CNC(=O)NC3CCCCC3)cc2o1 +O=S(=O)(NCC(O)C1CC1)c1ccccc1OC(F)(F)F +O=C(Nc1nnc(-c2ccco2)o1)c1cc(-c2ccccc2)on1 +COc1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)nn1 +CC(C)CNC(=O)c1nccn1Cc1ccccc1 +CCCc1nc(COc2ccc(N(C)S(C)(=O)=O)cc2)cs1 +CCc1cccc(C)c1-n1nnnc1C(C)(C)N1CCOCC1 +Cc1nnc2n1CCN(c1ncnc3scc(-c4ccccc4)c13)C2 +CS(=O)(=O)N1CC2CCCN2c2cc(C(F)(F)F)ccc21 +CC(C)CNC(=O)c1ccc(-c2ccc(F)cc2F)nc1N +CCOC(=O)c1cnn2ccn(Cc3ccc(F)cc3)c12 +CC(=O)Nc1ccc(OC(C)C(=O)NCCc2ccccc2C)cc1 +CNC(=O)c1ccc(NCc2nc(C)cs2)cc1Cl +CCCn1cc(Cl)cc1C(=O)NCCc1ccc(O)cc1 +CC(C)Oc1ccc(S(N)(=O)=O)cc1OC1CC1 +CS(=O)(=O)c1cccc(Oc2ccc(N)cc2F)c1 +Cc1csc(COC(=O)c2cc(C)[nH]c(=O)c2)n1 +CC(NC(=O)N1CC2CCC1C2)c1ccc(C#N)cc1 +COc1ccc(C)cc1CC(=O)N1CCCC(N2CCNC2=O)C1 +O=C(Nc1cc(N2CCCC2)ncn1)NC12CC3CC(CC(C3)C1)C2 +O=C(NCc1cccc(-c2ccccc2)c1)c1cc2n(n1)CCCO2 +CC(C)S(=O)(=O)NC1CCN(c2ccccc2)CC1 +CCC(=O)Nc1cccc(C(=O)N2CC(C)OC(C)C2)c1 +COCCOc1ccccc1NC(=O)NCc1ncc[nH]1 +Cc1ccc(Cl)cc1NC(=O)Cn1nnc(-c2cccs2)n1 +COc1cccc(C(=O)N2CCCC2CC(=O)c2ccccc2)c1 +CC1(C)OCC2(CO1)CN(C(=O)c1ccc3[nH]cnc3c1)C2 +CS(=O)(=O)NC(c1ccc(F)cc1)c1cccs1 +COC(=O)c1ccc(-c2csc(NC(=O)C3CCCO3)n2)cc1 +Cc1ccc(-c2nnc(NC(=O)Cc3ccc4c(c3)OCO4)o2)cc1 +CC1CN(C(C)c2nc3cc(F)c(F)cc3[nH]2)CC(C)O1 +COc1ccccc1NC(=O)NCCCN(C)c1ccccc1 +N#Cc1nnn(-c2ccc(O)cc2)c1-c1ccc(F)c(F)c1F +Cn1ccc(C(=O)N2CCN(c3nccs3)CC2)cc1=O +O=C1NCCCC1Nc1cc(-c2ccccc2F)nc2ccnn12 +CC(NC(=O)C1CCOC1)c1cccc(Cl)c1 +O=C(c1ccc(SCc2cccnc2)cc1)N1CCC(O)C1 +CC(C)(C)C(NC(=O)CSc1ccc(C(F)(F)F)cn1)C(N)=O +NC(=O)C1CCN(C(=O)Cc2c[nH]c3ccccc23)c2ccccc21 +CCOc1cc(NCC2CCCO2)nc(C2CCCCC2)n1 +Cc1ccc(C(NC(=O)c2nonc2C)c2ccncc2)cc1 +CCC(NC(=O)COc1cccc(N)c1)C(C)C +Cc1cc2nnn(CC(C)NC(=O)C(C)C)c2cc1C +Cn1cnc(CNC(=O)C2CCCC2NC(=O)OC(C)(C)C)n1 +NC(=O)C1CCC(CNC(=O)CCCc2cc(F)ccc2F)O1 +COCC(=O)N1CCC(NS(=O)(=O)Cc2cccc(F)c2)CC1 +OCCCn1nnc(CO)c1CCC1CCCCC1 +O=C(c1csnn1)N1CCC2(CC1)CN(CCO)c1ccccc12 +COc1cc(F)c(S(=O)(=O)N(C)C2CCCC(C)C2)cc1OC +NC(=O)c1ccc(COc2ccccc2C(F)(F)F)cc1 +CCC(C)CSc1nnc(NCC2CCCO2)s1 +O=C(c1ccccn1)N1CCN(C(=O)c2cccc3ncccc23)CC1 +CCCOc1cc2c(cc1OC)C(C1CCCO1)NCC2 +O=C(Nc1cccc(C=Cc2ccccn2)c1)c1cnccn1 +Cc1cc(NC(=O)c2ccc3c(c2)CCCN3)on1 +CN(C)C(=O)COC(=O)c1ccc(NC(=O)CC#N)cc1 +O=C(CCn1ccc2ccccc21)Nc1cccc2cnccc12 +CCN(C(=O)CSc1nnc(SC)s1)c1ccccc1 +CS(=O)(=O)NC1CCCN(C(=O)c2sccc2C#N)C1 +CS(=O)(=O)NCCSc1nnc(-c2ccccc2)o1 +Cc1cc(C)nc(-n2ncc(C#N)c2NC(=O)CCc2ccccc2)n1 +CCCc1nc(C)sc1-c1nnc(NC(C)=O)o1 +O=C(NCC#CCOc1cccnc1)c1ccc2ccccc2n1 +CCOc1ccc(N(CCC#N)C(=O)c2ccsc2)cc1 +NC(=O)CCC(=O)c1ccc(Br)cc1 +Cc1cc(Br)ccc1C(=O)NC(C)C(=O)NC(C)(C)C +CC1=C(C(=O)NCc2cnc(OCC(C)C)c(Cl)c2)CCCO1 +CC1CCCCN1C(=O)CN1CCN(c2cccc(Cl)c2)C1=O +O=C(c1ccc2nccn2c1)N(Cc1ccsc1)C1CCCC1 +COc1cc(CNC(=O)NCCc2cccc(Cl)c2)ccn1 +Cc1cc(C(=O)N(Cc2nc3ccccc3c(=O)[nH]2)C(C)C)[nH]n1 +Fc1ccc(C2NCCc3ccc(C(F)(F)F)cc32)nc1 +CC(CO)NC(=O)Nc1ccc(OCC(F)(F)F)nc1 +CCCCNC(=O)Cc1csc(NC(=O)C2CC2)n1 +CCOCc1cccc(NC(=O)c2c[nH]nc2-c2ccccc2F)c1 +CC(=O)N1CCN(Cc2nccn2C)CC(O)C1 +O=C(CCc1ccco1)Nc1cc(F)ccc1OCC1CCCO1 +Cc1cnccc1NC(=O)c1cnn(-c2ccccc2F)c1C +Cc1ccc(NC(=O)C2CC(=O)Nc3ccccc32)cc1F +COc1ccc(Nc2ncnc3[nH]cnc23)cc1Cl +O=C(NC1CCCNC1=O)c1cc2ccccc2cc1OC(F)F +Cn1nnnc1Sc1ccc(N)c(OCC2CC2)n1 +Cc1cc(F)ccc1NCc1cccc(C(N)=O)c1 +COCCC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCCCC2)c1 +Fc1ccccc1-c1noc(-c2ccc(NCc3cccnc3)nc2)n1 +CCc1ccccc1C(=O)N1CCC(n2ccnn2)CC1 +COCCn1nc(C(=O)Nc2ccc(SC)cc2)ccc1=O +CCn1cc(S(=O)(=O)N(C)c2ccc(Cl)cn2)cn1 +Cc1nc(C(C)C)sc1C(=O)NC(C)Cn1cccn1 +CNS(=O)(=O)c1cc(NC(=O)c2cnc(C)cn2)ccc1C +COc1cc(F)c(S(=O)(=O)N2CCCC(C)C2)cc1OC +Cc1c(C)n(-c2ncc(C(F)(F)F)cc2Cl)[nH]c1=O +CC1COC(c2ccccc2Cl)CN1C(=O)c1ccc(=O)[nH]c1 +COc1ccc2c(c1)C1(CCN(C(=O)C3CCCC3)C1)C(=O)N2 +CN1CCN(S(=O)(=O)Cc2ccc(C(F)(F)F)cc2)CC1 +Cc1ccc(C)c(CN2CCc3cc(S(N)(=O)=O)ccc32)c1 +Clc1ccccc1-c1noc(OCc2cccnc2)n1 +Cc1ccc(CNC(=O)COc2ccccc2O)cc1 +CCNS(=O)(=O)c1cc(Br)c2cccc3c2c1CC3 +CCC(C)CC(=O)N1CCC(n2cc(C3CCCC3)nn2)CC1 +CC(c1ccccc1)N1CCN(C(=O)CN2CCOCC2)CC1 +CC(C)c1noc(-c2cn(CCCc3ccccc3)nn2)n1 +Cc1nccn1-c1ncccc1NC(=O)CCNC(=O)C(C)(C)C +O=C(COc1cccc2c1NC(=O)CO2)NCCCc1ccccc1 +CCNC(=O)CC1Sc2ccc(C(F)(F)F)cc2NC1=O +COc1cccc(C=C2OC(=O)c3c2cc(C)[nH]c3=O)c1OC +Cc1ccc(C(=O)N2CCCC3(CCC(=O)N3CC3CC3)C2)cn1 +COc1ccc(CCNCc2cn(-c3ccccc3)nc2C)cc1 +Cc1cc(C)n(CC(=O)NCCN2CC(C)OC(C)C2)n1 +COc1cccc(-c2nc3ccccc3n2CC#N)c1 +COc1ccccc1NCC(=O)Nc1ccc(F)c(F)c1 +CCc1nc(CN2CCN(Cc3cnc(C4CC4)s3)CC2)cs1 +COC(=O)NC(C)(C)C(=O)N1CC(c2ccc(OC)cc2)CC1C +O=C(NCc1ccccc1F)Nc1cccc(CN2CCOC2=O)c1 +COC(=O)c1cccc(C(=O)N(C)Cc2cccc(F)c2)c1 +CCCNC(=O)COC1CCN(C(=O)OC(C)(C)C)CC1 +COC(=O)Cn1ccnc1-c1ccccc1Cl +CSc1cccc(NCC(=O)N(C)C(C)C)c1 +CNC(=O)c1ccc(S(=O)(=O)Nc2ccc(OC)nc2)cc1 +Cc1ccc2[nH]nc(C(=O)Nc3ccc4c(c3)OCCCO4)c2c1 +Cc1c(CNC(=O)Nc2ccc(OC(C)C)cc2F)cnn1C +Cc1ncc(CNc2ccccc2SC(F)F)s1 +CCCNC(=O)C1CCCN(C(=O)NCC(F)(F)F)C1 +Cc1cc(C)cc(CCNC(=O)CNC(=O)OC(C)(C)C)c1 +CN(Cc1cnn(C)c1)C(=O)Cn1ccc(C(F)(F)F)n1 +CCC(=O)N1CCCCCC1c1noc(-c2ccccc2)n1 +COCC(C)NC(=O)NCCC(=O)Nc1cccc(Cl)c1C +Cc1cc(C)nc(SCC(=O)C(C#N)c2ccccc2)n1 +CSc1ccc(OCC(=O)N2CCc3ccccc32)cc1 +CCOc1ncccc1CNC(=O)CCc1nc(C)no1 +CCCNC(=O)C(C)NC(=O)Nc1ccccc1C +N#Cc1c(CSc2ccccn2)cn2ccccc12 +Cn1cc(NC(=O)NC2CCN(c3c(F)cccc3F)C2=O)cn1 +COC(=O)CCSc1nc(-c2ccccc2)c[nH]1 +O=C(NCc1cc(Cl)ccn1)Nc1ccccc1F +NC(=O)COc1cccc(NC(=O)C2CC3CCC2C3)c1 +CC(=O)Nc1ccc(NCC(O)c2ccc3c(c2)OCO3)cc1 +CCCc1c(CO)nnn1-c1nc(-c2ccc(F)cc2)cs1 +CCn1ncc2c(C(=O)OCC#N)cc(-c3cccs3)nc21 +CCC(=O)Nc1sc(Cc2ccccc2)c(C)c1C(N)=O +Cc1ccc(S(=O)(=O)NCC#CCOc2ccc(C)nc2)cc1 +Cc1n[nH]c(C)c1CCNc1nccc(C2CCCC2)n1 +N#Cc1ccccc1NC(=O)c1nc(-c2ccncc2)no1 +NC(=O)Nc1cccc(C(=O)NCC(=O)OCc2ccccc2)c1 +Cn1c(=O)n(C)c2cc(S(=O)(=O)Nc3nccs3)ccc21 +CN1C(=O)CCC12CCCN(C(=O)c1ccsc1)C2 +CCCNc1nnc(SCC(=O)Nc2nc(C)cs2)s1 +CC(c1ccccc1)S(=O)(=O)c1nnc(N2CCCC2)s1 +CCNc1ccccc1C(=O)Nc1ccccc1F +CC(C)c1cc(C(=O)NCCc2cnn(-c3ccccc3)c2)on1 +Cc1cc(OCC(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)no1 +CC(=O)c1ccc(OCCCC(=O)Nc2ccc(F)cc2F)cc1 +O=C(NCCc1cccnc1)c1coc(COc2ccccc2)n1 +COc1c(C)cnc(COc2cccc(O)c2)c1C +COc1cccc(NC(=O)c2cccc(S(=O)(=O)NC3CC3)c2)c1 +COc1cc(CNC(=O)N(C2CC2)C(C)c2ccco2)ccn1 +CC(=O)Nc1cc(Cl)cc(-c2nc3ccccc3[nH]c2=O)c1 +CCc1cccc(NC(=O)NCc2cnc(C)s2)c1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2c(C)n[nH]c2C)cc1Cl +COCC(C)NC(=O)CN1CCN(c2ccc(F)cc2)C1=O +CCOC(=O)c1c(NC(C)=O)sc2c(OC(C)=O)cccc12 +O=C(c1ccoc1)N1CCOC(COc2cccc(F)c2)C1 +CC(C)c1nc(CN(C)C(=O)c2cn3cc(Cl)ccc3n2)no1 +CC(C)(C)OC(=O)N1CCCC1C(=O)N1CCCC(n2cncn2)C1 +NC(=O)C1(CNC(=O)CCc2nc3ccccc3s2)CCOCC1 +O=C(CCn1ccc2ccccc21)NCc1cc2ccccc2[nH]1 +Cn1cccc1CNC(=O)c1cccc2c1ccn2C +NC(=O)c1cc(N)n(-c2cccc(C(F)(F)F)c2)n1 +CC1=CC(C)(C)N(C(=O)CSc2nnc[nH]2)c2ccc(C)cc21 +CCc1ccc(C(C)NC(=O)C(C)N2CCOC(C)(C)C2)cc1 +COc1cc(Cl)c(-c2cc(N)on2)cc1Cl +CCC(C)N(C)c1ccc(N)c(OCC(C)C)n1 +CC(C)c1nnc(NC(=O)c2cc3c(Cl)cccc3n2C)s1 +Cc1sc2ccccc2c1S(=O)(=O)NCC1CC1 +CCn1nc(C(=O)NC2CCCc3ccccc32)c(=O)c2ccccc21 +CN(CC1CC1)C(=O)CCn1cc(Br)cn1 +CCCN(CC#Cc1ccccc1)C(=O)c1cc2cccnc2nc1C +CC(=O)Nc1ccc(NCCC(=O)c2cccs2)cc1 +Nc1cnc(CCOc2ccc3ccccc3c2)nc1 +COc1ccc(C)cc1NCc1ccccc1C(N)=O +CCOc1cccc(CNC(=O)Nc2ccc(C#N)cc2)c1 +Cc1cccc(NC(=O)NCC(=O)Nc2nc3c(s2)CCC3)c1 +Cc1nc(CNC(=O)Nc2cc(Cl)ccc2F)no1 +Cc1cc(C(=O)NC2C(c3cncnc3)CC(O)C2O)c(C)o1 +CC(C(=O)NC1CCCC1)N1CCN(C(=O)c2cccn2C)CC1 +CCOc1cc(F)ccc1NC(=O)c1ccc(OCC)c(OC)c1 +N#CC(CCC(=O)N1CCCC1)c1c[nH]c2ccccc12 +Cc1nnc2ccc(NCC3(c4ccncc4)CC3)nn12 +c1ncn(Cc2nnc(SCCC34CC5CC(CC(C5)C3)C4)o2)n1 +O=c1nc(Nc2ccc3c(c2)OCCO3)[nH]nc1Cc1ccccc1 +CCOC(=O)c1cccc(NC(=O)c2ccc(C)s2)c1 +CN(Cc1ccccc1)C(=O)COc1cc(=O)n(C)c2ccccc12 +Cc1csc(=O)n1CCC(=O)NCc1ccc(OC(F)F)cc1 +Cc1ccccc1CC(=O)NC(C)CN1CCCC1=O +CCOCC1CCCN(C(=O)c2ccc3c(c2)NC(=O)CS3)C1 +Cc1cccc(C(C)(C)CNC(=O)CCCC(=O)N(C)C)c1 +O=C(NCCC1CC2C=CC1C2)c1c[nH]nc1-c1cccc(F)c1 +Cc1ccc(CNC(=O)Nc2cccc(N3CCNC3=O)c2)cc1 +O=C(COc1nnc(-c2ccccc2)o1)NC1CCCCC1 +Brc1ccc(NCc2cccnc2)nc1 +CS(=O)(=O)c1cccc(NCC(=O)Nc2cccc(Cl)c2)c1 +CSc1nnc(C)c(CC=Nc2ccc(F)cc2F)n1 +COCCNC(=O)c1nn(-c2ccccc2)c(=O)c2ccccc12 +COC(=O)CNC(=O)CS(=O)(=O)c1ccccc1 +CC1CN(CCC(=O)Nc2sccc2C(N)=O)CCO1 +Cc1ncsc1C(=O)Nc1nc2cc3c(cc2s1)OCCO3 +CCCn1c(=O)c2c(nc3n(C(C)CC)c(C)c(C)n23)n(C)c1=O +O=C(c1ccnc(OC2CCC2)c1)N1CC=C(c2cccs2)CC1 +CC(C)c1cc(NC(=O)Cn2cccc(C(F)(F)F)c2=O)on1 +Cc1n[nH]c2c(NCc3ccc4c(c3)OCO4)ncnc12 +CC(NC(=O)Cn1cnc(C2CCC2)cc1=O)c1cccs1 +CCOC(=O)Cc1csc2nc(-c3ccco3)c(N)n12 +COc1ccc(CNS(=O)(=O)c2ccc(C)c(C(N)=O)c2)cc1 +Cc1ccnc2nc(C(=O)N(C)c3ccc(F)c(F)c3)nn12 +N#Cc1ccccc1COC(=O)CNC(=O)c1cccc(F)c1 +CCCCC(=O)N1CCCC1C(=O)c1cc(F)ccc1OC +CCOC(=O)CCNC(=O)N=c1[nH]cc(C)s1 +Nc1ccc2c(c1)CCN2C(=O)C1Cc2ccccc2O1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)CCc1ccco1 +CCNC(=O)CN1CCN(C(=O)Cc2cccnc2)CC1 +COc1ccccc1OCCN(C)S(=O)(=O)c1cccnc1 +CC(NC(=O)Cn1cnc2ccccc2c1=O)c1ccncc1 +Cc1cc(C(=O)NC2CCCC(C)C2C)cc(S(N)(=O)=O)c1C +CC1CCCCN1S(=O)(=O)c1ccc(C(F)(F)F)cc1 +CCS(=O)(=O)NCCn1nc(C2CC2)cc1C1CC1 +O=C1NC2(CCN(C(=O)c3cccnc3)CC2)CC1c1ccccc1 +CC(NCc1nc(-c2ccco2)no1)c1cn2ccsc2n1 +Cc1ccc(NC(=O)N2CCC(c3nnc(C4CC4)o3)CC2)cc1C +COc1cccc2cc(C(=O)Nc3nnc(C4CCCCC4)o3)oc12 +O=C(CCSc1ccccc1Cl)Nc1nccs1 +CC(c1ccccc1)n1cc(Br)cn1 +Cc1csc(N2CCCN(C(=O)Nc3cccnc3)CC2)n1 +Cc1cc(N2CCC(Cc3ccccc3)CC2)n2ncnc2n1 +CC1CCN(C(=O)CN2CCOc3ccc(F)cc32)CC1 +Cc1nc(C(=O)Nc2cc(Cl)ccc2C)cs1 +CC(C)c1cc(Br)ccc1NC(=O)NCc1ccccn1 +CCOC(=O)N1CCN(C(=O)CCn2cc(C)cn2)CC1 +Cc1cc(C)cc(C(=O)N2CCC(Oc3cccnc3)CC2)c1 +CCN1C(=O)COc2ccc(-c3cc(C#N)c(N)o3)cc21 +Cc1ccoc1C(=O)Oc1cccc(NC(=O)CN2CCCC2=O)c1 +CCS(=O)(=O)N1CCCC(C(=O)N2CCc3ccccc3C2)C1 +O=C(CC1C=CCC1)NC1CCN(c2ccc(F)cc2)CC1 +CN(Cc1cnn(C)c1)C(=O)NCc1csc2ccccc12 +COC(=O)c1cc(CNC(=O)c2ccc(=O)n(C)n2)ccc1OC +CN(CC(=O)NCCc1c[nH]c2cc(F)ccc12)C(=O)OC(C)(C)C +O=C(Nc1cccc2cnccc12)N1CCOCC(O)C1 +COc1cccc(CSc2ncc(C#N)c(N)n2)c1 +COCc1ccc(C(=O)N2CCCC(CNS(C)(=O)=O)C2)cc1 +COCCn1c(S(=O)(=O)C(C)C(=O)NC2CC2)nc(C)c1C +CCC(CC)C(NC(=O)C1CCN(C(C)=O)CC1)c1cccs1 +O=C(NCCNC(=O)c1ccn2cncc2c1)c1ccc(Cl)cc1 +COC(=O)C(Cc1ccc2c(c1)OCO2)NC(C)=O +CCCNc1ccc(C#N)cc1NC(=O)CN1CCCCC1=O +O=C(Cc1ccc2ccccc2c1)NCc1ccccc1-n1ccnc1 +CCN1CCN(C2=NCCN2C(=O)c2ccccc2C)CC1 +COc1nccnc1NC1CCN(C(=O)c2sccc2C)CC1 +CCc1noc(CN(C)C(=O)c2scnc2C2CC2)n1 +COC(=O)CNC(=O)C(C)Sc1ccccc1C +O=C1CN(C(=O)Cc2csc(-c3cccc(Cl)c3)n2)CCN1 +CC1CN(Cc2cnc3ncccn23)CC(c2ccccc2)O1 +Cc1nc(N2CCOCC2)cc(N2CCN(C(=O)C(C)(C)C)CC2)n1 +CN(Cc1cnn(C)c1)C(=O)CN1CCN(CCO)CC1 +O=C(COc1ncnc2c1cnn2-c1ccccc1)NCc1ccco1 +CCOCc1cccc(CNC(=O)c2ccc(C)[nH]c2=O)c1 +O=C(c1ccc(C(F)(F)F)cc1)N(CCO)C1CC1 +Clc1ccc(OCCC2OCCO2)cc1Cl +O=C1COc2ccc(C(=O)NCCc3ccccc3)cc2N1 +COc1cc(C(C)=O)ccc1OCC(=O)NC(C)C +O=C(c1cc[nH]n1)N1CCN(C(=O)c2ccccc2F)CC1 +CCOC(=O)CCC(=O)Nc1ccc(Br)c(Cl)c1 +CC(NS(=O)(=O)c1cn(C(C)C)cn1)c1csc(C2CC2)n1 +CCc1sc(-c2nnc(CSc3nncn3C3CC3)o2)cc1C +O=c1oc2cccnc2n1CCSc1nc(-c2cccs2)n[nH]1 +COc1cc2cc(CNc3ccc(C)cc3)c(=O)[nH]c2cc1OC +CC(=O)c1cccc(OCC(O)COc2cccc(F)c2F)c1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)C(=O)c1ccc(C)nc1C +CCOC(=O)CCC(C)NC(=O)c1ccc(C#N)cn1 +COc1ccccc1NC(=O)CNc1ccc(F)c(F)c1 +O=C(C1CCCC1)N1CCNCC1c1nc2ccccc2[nH]1 +CNS(=O)(=O)c1cccc(CNc2ccc(C#N)c(Cl)c2)c1 +COc1ccc(NC(=O)OCc2ccc3c(c2)OCO3)cc1 +COc1ccnc(NC(=O)c2cccnc2OCC(C)C)c1 +CCOc1ccc(NC(=O)NCC(F)(F)F)cc1Cl +Cc1cnc(C(=O)Nc2ccc3c(c2)OC2(CCCCC2)O3)cn1 +CN(C)c1nc(-c2ccccc2CN2CCOCC2)n[nH]1 +CC(N)C(=O)c1cc2cccc(Br)c2s1 +NS(=O)(=O)CC1CCCN1C(=O)c1ccc(Br)cc1 +CCc1ccsc1C(=O)NCCCNc1ncccn1 +CCCC(C)NC(=O)NCC1COc2ccccc2O1 +Cc1noc(COC(=O)c2ccc3nc(C)c(C)nc3c2)n1 +COCC(=O)Nc1cccc(C2=NC(=O)CC(C)=N2)c1 +O=C(c1ccccc1)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1 +COc1cccc(C(=O)Nc2cccnc2)c1OC +Cc1ccc2c(c1)CCCN2C(=O)COc1ccccc1O +COc1ccccc1C(C)NC(=O)CNC(=O)c1ccc(C)s1 +C=CCN(Cc1cccc(C#N)c1)C(=O)c1ccc2[nH]cnc2c1 +CCN(CC(C)C#N)C(=O)c1cc2cc(Cl)ccc2[nH]1 +O=c1nc(SCc2ccc(F)cc2)c2c(n1CCCO)CCC2 +CN(CC(=O)NC1CC1)C(=O)c1ccc(Br)cn1 +CCCC(=O)N1CCC(C(=O)OCc2ccccc2F)CC1 +COc1nccnc1N1CCC(N(C)C(=O)NC(C)C)C1 +CCN(CC)C(=O)CCCNC(=O)c1ccccc1O +CSc1ccc2nc(NC(=O)c3ccno3)sc2c1 +CCN1C(=O)C(O)(CC(=O)c2cc(C)ccc2C)c2ccccc21 +CCC(CC)c1nc2cc3c(cc2n1CC(C)C#N)OCCO3 +Cc1cc(C)c(S(=O)(=O)Cc2ccccc2)c(=O)[nH]1 +O=C(c1ccnc(Oc2ccccc2)c1)N(Cc1ccccn1)C1CC1 +COc1cccc(-c2nc(C3CC3)c(C#N)s2)c1OC +Cc1nn(C)cc1S(=O)(=O)N1CCN(c2ccccc2F)CC1 +Brc1cnn(-c2ccc3c(c2)CCO3)c1 +CC(=O)N1CCC2(C1)CN(S(=O)(=O)c1cccs1)C2 +Oc1ccc2c3c(ccc2c1)CCNC3c1ccnnc1 +COc1cccc(C(=O)Nc2ccnc(C)c2)c1OC +Cc1ccc(-c2cn(C3CN(C(=O)C4CCC4)C3)nn2)cc1 +CCCCCC(=O)Nn1c(C)nc2ccccc2c1=O +COC(C)C(=O)Oc1ccccc1-c1ccccc1 +CC1CN2CCCC2CN1C(=O)c1csc(-c2ccsc2)n1 +Cc1ccc(NC(=O)C(C)CS(=O)(=O)N2CCNCC2)c(C)c1 +CCN(CC)C(C(=O)N(C)Cc1ccccn1)c1ccccc1 +CCCc1nnc(NC(=O)C2CCN(C(=O)C3CC3)CC2)s1 +CCOC(=O)N1CCC(NC(=O)c2nnn(-c3ccccc3)n2)CC1 +Cc1cccc(C=Cc2ccn(CCCO)c(=O)c2)c1 +CC(Sc1c(Cl)cccc1Cl)C(=O)N(C)C +CC(NCC(=O)N1CC(=O)Nc2ccccc21)c1ccccc1Cl +CCSc1cccc(C(=O)Nc2nc(-c3ccccn3)cs2)c1 +CCc1onc(C)c1NC(=O)c1cc(C)n(Cc2ccccn2)c1C +COc1cc2[nH]c(=O)n(C(C)c3ccc(F)cc3)c(=O)c2cc1OC +Nc1cc(N)nc(SCC(=O)Nc2nc3c(s2)CCCC3)n1 +Cc1n[nH]c(C)c1NC(=O)CSc1nnc(NCC(C)C)s1 +CC(Sc1nc2ncccn2n1)C(=O)NC(C)(C#N)C(C)C +CNC(=O)C1CN(Cc2cc(C#N)ccc2F)CCO1 +CCOc1cc2c(cc1O)C(COc1ccccc1)NCC2 +Cc1cc(CNc2ccc(C(=O)NC3CCOCC3)cc2)no1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)c1ccoc1 +N#Cc1nc(-c2cccs2)oc1NCCCn1ccnc1 +O=c1[nH]c(CCc2ccccc2)nc2ccsc12 +Cc1ccc(C(CNC(=O)Nc2ccccn2)N2CCOCC2)o1 +CCCCn1nc(C(=O)Oc2cccc(F)c2)ccc1=O +COc1ccc(C2CC(=O)Nc3cc(OC)cc(OC)c32)c(OC)c1 +CCN(CCO)C(=O)CCc1ccc(O)c(N)c1 +CCc1nnc2ccc(NC3CCCCCC3)nn12 +CCCNC(=O)C(C)NC(=O)Nc1cccc2ccccc12 +Cn1c(CCc2ccccc2)nc2cc(N)ccc21 +Cc1cnccc1-c1cc(NCc2ccncc2)nc2[nH]ccc12 +C=CCn1cnc2c1c(=O)n(CC)c(=O)n2-c1ccc(F)cc1 +O=C(C1CC2C=CC1C2)N1CCc2ccccc2C1 +O=C(Nc1cccc(Br)c1)c1scnc1C1CC1 +COCCOc1cc(C)ccc1NC(=O)N1CCC(CO)CC1 +CCCNC(=O)CN1CCNc2cc3c(cc21)CCCC3 +CCc1noc(CC)c1CC(=O)N1CCC(C)(C)C1 +COCC(C)(CCO)NC(=O)c1cccc2cc[nH]c12 +COc1cc(C)c(C)cc1-c1ccc(C(N)=O)c(N)n1 +N#Cc1c(Cn2cc(Br)cn2)cn2ccccc12 +Cc1ccc(NC(=O)N2CCCC(C)C2)c(OCC(=O)N(C)C)c1 +CCN(Cc1cccc(NC(=O)Nc2ccccn2)c1)C(C)=O +O=C(OCC(F)(F)F)c1cnn2c(-c3ccccc3)ccnc12 +O=C(COc1cc(F)ccc1F)c1ccc2c(c1)COC2 +CN(C)C1(C(=O)NCc2nc(C3CC3)no2)CCc2ccccc21 +CC1CN(Cc2ccccc2NC(=O)C2CC(=O)N(C)C2)CC(C)O1 +O=C(c1ccc(Br)cc1Cl)N1CCOCC1C1CC1 +COC(=O)CN(C(=O)c1ccc(C)cc1)n1c(C)ccc1C +CCSc1ccccc1NC(=O)CCC(=O)OC +O=C(Cn1cncn1)NCCc1ccc(Cl)cc1 +CS(=O)(=O)NC1CCCN(C(=O)C2(c3ccc(F)cc3)CC2)C1 +CC(C(=O)N1CCCC1Cn1cccn1)n1ccnc1 +COCCSc1nnc(COc2ccc(Cl)cc2)n1C +CCCC(C(=O)Nc1cccc(N)c1)n1ccc(C)cc1=O +Cn1cc(NC(=O)NC(CO)Cc2c[nH]c3ccccc23)cn1 +Cc1ccc(C(=O)NCCNC(=O)c2ccc(O)cc2)c(C)n1 +COc1ccc(N(C)C(=O)c2ccc(C(=O)N(C)C)cc2)cn1 +Cn1ncc(C#N)c1NC(=O)NCc1cccnc1OC1CCCC1 +Cc1cc(C)cc(NC(=O)CN(C)C(=O)c2ccccc2)c1 +CC1COCC(C)N1C(=O)c1cc2ccc(Cl)cc2[nH]1 +Cc1cccc(CN2CCCC3(CCN(S(C)(=O)=O)C3)C2=O)c1 +Cc1n[nH]cc1NC(=O)c1ccccc1-n1cccn1 +NC(=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1O +COc1ccc(Cl)cc1C(=O)Nc1cc(-c2cccnc2)no1 +Cc1ccc(S(=O)(=O)NC(C)c2ccccc2N)s1 +O=C(Nc1cccnc1)C1CCCN1C(=O)c1cc2sccn2c1 +N#Cc1ccccc1OCc1ccc(C(=O)NCc2ccccn2)o1 +COc1ccc(C2CC2C(=O)N2CCCC(c3ccn[nH]3)C2)cc1 +COc1ccc(C(=O)CSc2ccccc2)c(OC)c1OC +C#CCN1CCN(CC(=O)Nc2ccccc2Oc2ccccc2)CC1 +Cc1nc2c(C#N)cnn2c(C)c1CCC(=O)N1CCc2ccncc21 +COc1ccc(NC(=O)c2ccc(N3CCOCC3)cc2)cc1OC +CCCC(=O)NC(C)c1ccc(S(C)(=O)=O)cc1 +CCn1cc(C(=O)NCc2cc(C(C)C)no2)cn1 +COc1c(Cl)cccc1NC(=O)NCC(C)(C)N1CCOCC1 +CC(C)NC(=O)CSc1nnnn1-c1cccc(Cl)c1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1cccs1 +CCS(=O)(=O)NCCCNC(=O)c1cc(Cl)ccc1Cl +Cc1ccc(-c2nn3cnnc3s2)cc1NC(=O)C(C)C +COc1cc(C)c(Cl)cc1C(=O)CN1CCC(=O)CC1 +CCNC(=O)CNc1cc(NC(=O)C2CC2)ccc1C +Cc1cccc(CCNC(=O)Nc2nnc(C(F)F)s2)c1 +CC(=O)c1ccc(Nc2ncnc(-n3ccnc3)c2N)cc1 +COc1ccc(N2CC3(CCN(C(=O)N(C)C)C3)CC2=O)cc1 +Cn1ncc2c(Nc3cccc(N4CCCC4=O)c3)ncnc21 +Cc1ccc(NC(=O)NCCNC(=O)C2CC2)c(Cl)c1 +COc1cccc(CCNC(=O)c2cc3sccc3n2C)c1 +Cn1ccc(NC(=O)C2CC(=O)N(c3ccccc3F)C2)n1 +O=C(NCc1nc(C2CC2)no1)c1ccc(-n2cccn2)nc1 +Cc1nnc(NC(=O)NC(C)c2cccc(OC(C)C)c2)s1 +NS(=O)(=O)CCNC(=O)c1ccc(OC(F)(F)F)cc1 +Cc1nc(-c2ccc(N(C)Cc3ccccc3)nc2)[nH]c(=O)c1C +O=C(NCc1cc(Br)ccc1F)Nc1nccs1 +C=CCn1cccc(C(=O)Nc2ccc(OCC)cc2)c1=O +NC(=O)CSc1ccccc1C(=O)Nc1ccccc1 +O=C1NCC2(CCCN(C(=O)c3cn4ccsc4n3)C2)O1 +O=C(CSc1nnnn1-c1ccccc1)Nc1cccc(O)c1 +COCCCN(C)C(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +CC(C#N)Cc1ccc2cccc(N3CCOCC3)c2n1 +Cn1c(CN2CCN(S(C)(=O)=O)CC2)cc(=O)n(C)c1=O +COc1cc(NCc2ccc(F)cc2N)ccc1F +O=C(c1ccsc1)N1CC(OCc2ccncc2)C2OCCCC21 +CC(=O)N(C)Cc1cccc(NC(=O)N(C)C2CCCCCC2)c1 +CCOc1ccc(-c2noc(CSc3cc(C#N)ccn3)n2)cc1 +CC(=O)c1nn(-c2ccccc2Br)c(C)cc1=O +CC(CO)Nc1ccc(S(=O)(=O)N(C)C)cc1N +C=CCNC(=O)C(N)c1cccc(Br)c1 +NC(=O)N1CCCC1C(=O)NC1CCCC1c1ccc(Cl)cc1 +O=C(NCC1Cc2cccc(-c3ccncc3)c2O1)c1ccc(F)cc1 +CC1CCCN(S(=O)(=O)c2cccc(F)c2)C1 +CC(C)CC(=O)N1CCN(c2ccc(S(N)(=O)=O)cc2)CC1 +CC(NC(=O)CCCc1cc(F)ccc1F)(C(N)=O)c1ccccc1 +Cc1cc(Br)ccc1C(=O)N(C)CC(N)=O +O=C(COc1ccccc1F)N1CCN(c2ccccc2O)CC1 +CCOCC(=O)N1CC2CN(c3ccccc3)C(=O)C2C1 +O=C1CN(C(=O)CCCc2cccs2)c2ccccc2N1 +O=C(NCCn1nc(-n2cccn2)ccc1=O)c1cc2ccccc2o1 +Cn1c(=O)n(CC(=O)C(C)(C)C)c(=O)c2ccc(C(F)(F)F)nc21 +CCC(=O)Nc1ccc(SCc2ccc(C(=O)OC)o2)nn1 +CC(C)(C)c1cnc(CN2CCNC(=O)C2c2cccs2)o1 +CCOC(=O)c1nc(NCc2cccc(C)c2)c2c(C)noc2n1 +N#Cc1c(F)cccc1N1CCN(S(=O)(=O)N2CCCC2)CC1 +O=C(CCCNC(=O)c1cccs1)NC1CCCC1 +O=C(NCCc1cccs1)c1cncn1-c1ccc(F)cc1 +CCS(=O)(=O)N1CCN(C(=O)Nc2ccc(OC)c(C)c2)CC1 +CCOCC(=O)NCC#Cc1ccc(C(=O)N(C)C)cc1 +CCC(C)Sc1cc2c(cc1N)CCC(=O)N2 +O=C1NCCc2ccc(S(=O)(=O)Oc3ccc(F)c(F)c3)cc21 +CCOC(=O)c1ccc(-c2onc(C)c2Br)[nH]1 +CC1CCCCC1NC(=O)Cn1nnnc1C(C)(C)C +O=C(Nc1cccc(F)c1)Nc1cnn(CC2CCCO2)c1 +CCn1ccc(C(=O)N2CCCC2c2nc(C(C)C)no2)cc1=O +CNc1snnc1CSc1ccc(NC(C)=O)cc1 +CCOCCC(=O)NCCc1ccc(F)cc1C +CCCNC(=O)C1CCCN(c2ccc(-c3ccc(F)cc3)nn2)C1 +CC(C)NC(=O)c1[nH]cnc1C(=O)NCc1ccccc1F +COCCC(=O)Nc1cc(C(F)(F)F)ccc1C +O=C(NCc1cccnc1-c1ccccc1)c1ccco1 +Cc1cc2c(SCCc3c(C)noc3C)ncnc2s1 +NC(=O)c1cc2c(nc1-c1ccc3c(c1)CCO3)CCC2 +O=C(Nc1ccccc1N1CCOCC1)C1Cc2ccccc2O1 +Cc1cc(C)n2nc(C(=O)Nc3cccc(Cl)c3C)nc2n1 +COc1cc(C)cc(OC)c1OCC(=O)Nc1c(C)cc(C)cc1C +COc1ccc2[nH]cc(CC(=O)Oc3ccc(F)cc3)c2c1 +Cc1ccc(C(=O)Nc2n[nH]c(Cc3cccc(F)c3)n2)c(=O)[nH]1 +Cc1nc(CNC(=O)CCCOc2ccccc2C)n[nH]1 +Cc1nc2ccccc2n1CC(O)COc1ccc(Cl)cc1 +O=C(CCC(=O)N1CCCC1)c1ccc2c(c1)CCCC2 +CCOC(C)c1noc(CNc2ccc(Cl)cc2F)n1 +CNC(=O)C(CC(C)C)NC(=O)c1ccc(-c2nc(C)no2)cc1 +CCc1nnc(SCc2ccc(Br)cc2)n(N)c1=O +CC1CN(Cc2ccccc2NCC(=O)NC2CC2)CC(C)O1 +CCOC(=O)N1CCC2(CC1)OC(=O)C(C)=C2C(=O)NCCOC +CCn1c(C)nnc1SCc1cc(F)ccc1F +CC(=O)N1CCc2ccc(NC(=O)c3c(F)cccc3Cl)cc2C1 +Cc1ccc(-c2cc(C(=O)NCc3csc(C)n3)no2)cc1 +CCCc1n[nH]c(C2CN(C3CCN(C)C3=O)CCO2)n1 +CCSc1ccc(C(=O)N2CCC(NC(=O)C3CCC3)CC2)cn1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3ccc(F)cc3F)c2)n1 +O=C1NCCNC1c1ccc2nc(C3CC3)[nH]c2c1 +Cc1c(N)cccc1NC(=O)c1ccc(Br)cc1 +CCC(CC)c1cc(C(=O)NCC(C)(C)c2ccncc2)on1 +Nc1ccc(C(=O)CCC(=O)Nc2ccc3c(c2)OCO3)cc1 +COc1ccc(NC(=O)c2ccc3ccccc3c2)c(N)c1 +Cc1nc(-c2cccc(C(=O)N3CCC(Cc4ccccc4)C3)c2)no1 +CC(C)(C)C(=O)N1CCN(C(=O)NCC2CC=CCC2)CC1 +CC1CCN(C(=O)CN2CCc3ccc(Cl)cc3C2)CC1 +O=C(CCc1ccccc1)NCC#Cc1ccc(N2CCNC2=O)cc1 +C#CC1(NC(=O)CCc2scnc2C)CCCCC1 +CC(C(=O)Nc1ccc(CC#N)cc1)c1cccs1 +COc1ccc(Cn2nccc2NC(=O)c2ccccc2C)cc1 +CCCC(=O)NC1CCN(c2ccc(F)cc2)C1=O +O=C(NC1CC1)N1CCC(F)(F)C2(CCN(c3cccnc3)C2)C1 +Cc1ccncc1NS(=O)(=O)c1ccc(F)cc1C +CC(=O)Nc1ccc(-c2c(-c3ccccc3)ncn2C2CC=CC2)cc1 +O=C(NCc1ccncc1)C1(c2cccc(C(F)(F)F)c2)CC1 +CN(C(=O)c1ccc(F)cc1Cl)c1ccc(S(C)(=O)=O)cc1 +O=C(Nc1cc(N2CCOCC2)ncn1)c1ccc2ncsc2c1 +CCC1=C(C(=O)OC(C)C)C(c2ccc(F)cc2)NC(=O)N1 +Cc1n[nH]c(C)c1NS(=O)(=O)c1cc(Cl)cc(Cl)c1 +O=C(NCc1ccc2c(c1)OCCO2)c1cc2ccccc2[nH]1 +CCC(C)Nc1oc(-c2ccc(S(=O)(=O)N(C)C)cc2)nc1C#N +O=C1OC(C(=O)NC2CCC(O)CC2)Cc2ccccc21 +Cc1ccc(NCc2cn(C)nc2-c2ccncc2)cc1F +Cc1sc2ncnc(Oc3cccc(C(=O)NC4CC4)c3)c2c1C +Cc1cc(C(=O)COc2ccc(C#N)cc2)c(C)n1C1CC1 +CS(=O)(=O)N1CCCCC1C(=O)Nc1onc2c1CCCC2 +Cc1cnc(NC(=O)NCC2(c3ccccc3C)CCOCC2)s1 +COC(=O)C1(NC(=O)c2cccc(OCC(F)F)n2)CCC1 +COc1ccc(-c2n[nH]c(C)c2NC(=O)c2cc(F)cc(F)c2)cc1 +COCCOC(=O)c1c(C)nn(-c2ccc(F)cc2)c1C +Cn1nc2n(c1=O)CCN(S(=O)(=O)c1ccc3c(c1)CCO3)C2 +N#CC(Cc1ccccc1F)C(=O)N1CCOCC1 +CCOc1ccccc1OCC(=O)N1CCN(C(=O)C2CC2)CC1 +CCCOc1cc(CNc2ccc3c(c2)COC3)ccc1OC +COc1cccc(C(=O)N(CCc2cccs2)C2CC2)c1 +CSc1ccsc1C(=O)NCc1noc(-c2ccco2)n1 +COc1ccccc1C(=O)N1CCN(C(=O)c2cc(C)oc2C)CC1 +Cc1nc(CNC(=O)NC2CCOc3c(Cl)cccc32)oc1C +CC(C)S(=O)(=O)c1ccccc1NC(=O)NCc1ccnn1C +CCOc1cc(CNC(=O)N2CCCCC2c2cn[nH]c2)ccn1 +CC(=O)Nc1ccc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1 +CC1CN(C(=O)OC(C)(C)C)CCN1CC(=O)c1ccco1 +O=C(Cn1nc(N2CCOCC2)ccc1=O)NCc1ccco1 +Cc1cc(C(=O)NCC#CCOc2ccc(F)cc2F)c(C)o1 +CNC(=O)CN1CCN(C(=O)COc2ccccc2)CC1 +N#Cc1cnn(C(=O)c2cc3ccccc3[nH]2)c1N +Cn1c(C2CC2)nc2cc(NC(=O)CCOCC3CCCO3)ccc21 +Cc1cc(C)c2c(c1)C(NC(=O)c1cnccn1)CCO2 +O=S(=O)(Nc1cccc(Cn2cccn2)c1)c1ccc(F)cc1 +COc1ccc2c(c1)C=C(c1nc(C3CN(C)CCO3)no1)CO2 +CC(=O)Nc1ccc(NC(=O)COc2ccc(C)c(C)c2)cc1 +Cc1ccnc(N(C)CC2CCCCN2C(=O)OC(C)(C)C)n1 +Cc1cc(Cl)ccc1NC(=O)CS(=O)(=O)c1ccccc1 +COc1ccc(NC(=O)CSc2cc(C)ncn2)cc1 +O=C(NCCc1ccccc1)C1CCN(C(=O)c2cccs2)CC1 +CSc1ccccc1Cc1nc2cc(C#N)ccn2n1 +Cc1ccc(C(=O)Nc2ccc(C(F)(F)F)cc2)o1 +O=C(NCCO)C12CC3CC(CC(Cl)(C3)C1)C2 +CCC(C)NC(=O)Cn1cnc2c(oc3ccccc32)c1=O +COc1ccccc1OCCN(C)C(=O)C1CCCN1C(=O)C1CC1 +COc1ccc(C(C)C)cc1Cn1cc(N)ccc1=O +CCC1(CNC(=O)c2cn(C)nc2C(C)(C)C)CCC1 +Cc1ccc(S(=O)(=O)NC2CCN(C(=O)CC(C)C)CC2)cc1 +O=C(CN1CCOC1=O)NCc1cnn2ccccc12 +CC1(C)OC(N)=C(C(N)=O)C1c1ccc(Cl)cc1 +CC(C)OC(=O)C(C)n1c(N)nc2cc(F)c(F)cc21 +COCc1csc(NC(=O)NCCc2c[nH]c3cc(F)ccc23)n1 +Cc1nc2ccc(NC(=O)c3occc3C)cc2s1 +COc1cc2c(cc1OC)CN(C(=O)c1cc(C)on1)CC2 +OC1(CSc2nnnn2C2CC2)CCCCC1 +C=CCNC(=O)N1CCCC(c2nc(-c3ccc(F)cc3)no2)C1 +Cc1cnn(-c2ccc(C(=O)OCC3CCCCO3)cc2)c1 +Cc1ncsc1CNC(C)c1ccc(F)cc1 +CC(NS(=O)(=O)c1c[nH]nc1N)c1ccco1 +COC(=O)C(CO)NC(=O)Nc1cc(Cl)ccc1Cl +Cc1nc(C(=O)OCc2cc(-c3cc4ccccc4o3)on2)cs1 +Cn1cc(C(=O)Nc2ccc(SC3CCCC3)cc2)cn1 +Cc1nc2ncnn2c(C)c1CCC(=O)N1CCCC1(C)C +NC(=O)COc1cccn2c(-c3cccc(N)c3)nnc12 +Cc1cc(CN(C)C(=O)Nc2ccccc2-n2cccn2)no1 +O=C(Nc1ccc(Br)cn1)c1cc2c([nH]c1=O)CCCC2 +CC(C)Cn1cc2c3c(cccc31)CN(C(=O)c1cnccn1)CC2 +CNC(=O)CNC(=O)CC1COc2ccc(C(=O)N(C)C)cc2N1C +CC(Cc1ccc(O)cc1)NC(=O)NCC(=O)NCc1ccco1 +Cc1nn(C)c2c1N(C(=O)Cc1ccccc1OC(C)C)CCS2 +CCCc1nc(SC)ncc1C(=O)NCc1ccccc1F +COc1ccc(C(NC(=O)c2cccnc2)C(C)C)cc1 +CC1CCCC(NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)C1C +Cc1nc2ccccc2n1Cc1cc(C(=O)N2CC=CC2)n[nH]1 +COc1ccc(-n2nnnc2C(C)(C)Nc2ccccc2OC)cc1 +O=C(CC1NC(=O)c2ccccc2NC1=O)NCC1CCCO1 +CCn1cnnc1CNC(=O)NC(C)c1cc2ccccc2o1 +Cc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1N +CC(C)N(Cc1ccccc1)C(=O)c1ccccn1 +Cc1nn(-c2ccccn2)c2nc3[nH]nc(N)c3cc12 +CCCOc1cccc(-c2cc(C(C)(C)O)c(=O)n(C)n2)c1 +CC(=O)N1CC(C(=O)Nc2ccc(C)cc2C)Oc2ccccc21 +Cc1occc1C(=O)NCC(=O)Nc1ccc2c(c1)COC2 +CCC1COCCN1S(=O)(=O)c1ccc(Br)cc1N +Cc1c(C(=O)N2CCCC2(C)C)oc2c1C(=O)CC(C)(C)C2 +CCOc1cc(CNc2ccccc2OC)ccc1O +COc1cc(C)c(S(=O)(=O)NCCNC(=O)C(C)C)cc1C +CC(C)(C)c1nnc(SCC(=O)Nc2ccccc2)n1N +CC(C)CC(=O)N1CCN(c2ccc(Cl)c(N)c2)CC1 +CC(CNC(=O)N(C)C(C)C)Oc1ccc(F)cc1 +CCC(C)N(C)C(=O)c1cc(Cl)cc(Cl)c1 +Cc1csc(C2CN(C(C)C(=O)Nc3nccs3)CCO2)n1 +COc1ccc(-c2csc(C#N)c2NC(C)=O)cc1C +CC(C)Oc1ccc(C(=O)Nc2ncccc2CO)cc1 +COc1cccc(OCC(=O)NC(c2ccccc2)c2ccccn2)c1 +CCN(CCO)S(=O)(=O)c1ccc(CC(C)C)cc1 +CC1=C(C(=O)NCc2cc(F)cc(F)c2)C(C)NC(=O)N1 +COc1ccc(NC(=O)c2cc(C3CC3)on2)cc1Cl +Cn1ccnc1C(=O)c1ccc(NC(=O)c2cc(F)cc(F)c2)cc1 +O=C(NC1(N2CCOCC2)CC1)c1ccc(Cl)cc1 +COc1ccc(CCC(=O)Nc2ccc(N3CCCC3)nc2)cc1 +CCc1cccc(NC(=O)N2CCCCC2CCN2CCCC2=O)c1 +NC(=O)Cc1ccccc1NC(=O)CC1C=CCC1 +CCn1nc(C(=O)Nc2nccs2)c(=O)c2cc(Cl)ccc21 +Oc1ccc(CNc2ccc(F)cc2F)cc1F +O=C1c2ccccc2NC(c2cccc(F)c2)N1Cc1ccco1 +COc1ccc2c(cnn2CCC(=O)N2CCOCC2)c1 +CCC(C)NC(=O)C(C)NC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +COc1ccc2c(ccn2CC(=O)N2CCc3ccccc3C2)c1 +COc1ccc(C(C)C)cc1C(C#N)c1ccc(N)cn1 +Cc1ccc(Cl)cc1NC(=O)CSc1nnc(C(C)C)o1 +CC(=O)N1CCC(CN(C)C(=O)Nc2cc(C)cc3cccnc23)C1 +CC=Cc1nnc(C(N)c2cc(F)c(F)cc2F)o1 +CCOC(=O)C1CCN(C(=O)c2cccc(C(=O)OC)c2)CC1 +CCOc1cccc(NC(=O)NCc2cccc(C#N)c2)c1 +COc1ccc(-c2c(N)nc(C)nc2C(F)(F)F)c(OC)c1 +CCCC(=O)NCC(=O)Nc1cc(OC)ccc1OC +COCCOc1ccccc1NC(=O)c1csc2c1CCCC2 +COCCN1CCN(C(=O)NC(C)c2ncc(C)s2)CC1=O +O=C(Oc1ccccc1)N1CCN(CCCn2ccnc2)CC1 +COC(=O)C(NC(=O)c1cnc(-c2ccccc2)s1)C(C)C +CCOCC1CCCN(C(=O)CNC(=O)CC2CCCCC2)C1 +CCn1c(SCC#N)nc2ccsc2c1=O +CC(=O)NC(C)C(=O)N1CCC(Cc2ccccc2)CC1 +O=C(c1cccc(F)c1)N1CCC2(CCCN2c2ncccn2)CC1 +CCCC(=O)NC1CCCN(c2ncccc2-c2nc(C)no2)C1 +O=C(Cn1c(=O)cnc2ccccc21)NCC1CCCO1 +CNC(=O)NCC(=O)NC(CC(C)C)c1ccccc1OC +COC(=O)c1ccccc1NC(=O)CSc1nn2cnnc2o1 +CCOC(=O)C(C)(C)n1c(-c2cccc(N)c2)csc1=O +O=C(Cc1c[nH]c2ncccc12)NCc1ccccc1Cl +Cc1ccc(-c2cn[nH]c2C2CCCN(C(=O)c3cccnn3)C2)cc1 +Oc1ccc(-c2csc(NCC3CCCO3)n2)c(O)c1 +CCN1CC(CN(C)C(=O)CCCNC(N)=O)Oc2ccccc21 +O=C(CCc1cnccn1)N1CCC2C(CCC(=O)N2CCCO)C1 +Cc1ccc2c(ccn2CC(=O)Nc2nc(-c3cccnc3)cs2)c1 +Cc1cc(C(=O)CSc2nc3ccccc3c(=O)[nH]2)c(C)n1C +c1ccc(-c2nc(CCNCc3cccnc3)co2)cc1 +Cc1ccc(F)cc1NCc1nc(C(F)(F)F)cc(=O)[nH]1 +COCCOc1ccccc1NS(=O)(=O)c1cccs1 +Cc1nc(CN2CC3CC(C(=O)NCc4ccco4)C(C2)O3)cs1 +CCc1noc(C2(NC(=O)c3n[nH]c4c3CCCC4)CCCCC2)n1 +OCc1c(-c2ccncc2)nc2cc(C(F)(F)F)ccn12 +COC1CCCC1OC(=O)C1CC1c1ccccc1F +CN(CC1Cc2ccccc2O1)C(=O)c1cn(-c2ccccc2)nn1 +CCCCNC(=O)COC(=O)c1n[nH]c2ccccc12 +COc1cc(-c2nc3c(n2O)C(=O)CC(C)(C)C3)cc(OC)c1OC +Cc1cc(C(=O)N2CC(OCc3ccncc3)C3OCCCC32)no1 +CCc1nnc(NC(=O)CCC(=O)c2ccccc2)s1 +CN(C)S(=O)(=O)N1CCN(c2ccccn2)CC1 +CC(=O)N1CCN(C2COc3ccc(F)cc3C2O)CC1 +N#CCCC(C#N)CN1CCOC(CNc2cccnn2)C1 +Cc1cc(C)n(CC2CN(CCn3cccn3)CCO2)n1 +Cc1cc(NC(=O)CCS(=O)(=O)c2ccccc2)on1 +CCCNC(=O)CCNC(=O)NC1CCc2c(F)cccc21 +Cc1cccc(C(C)C)c1NC(=O)NC(C)(C)c1nc(C)c(C)s1 +COc1ccc(CNC(=O)C(C)Sc2cccc(C)c2)cc1OC +CC(C)(C)OC(=O)NCC(=O)NCc1ccccc1-n1ccnc1 +CC(O)c1c(-c2ccccc2)nc2c(F)cccn12 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)C1Cc2ccccc2CN1 +Clc1ccccc1Cn1nnc2c(N3CCCCC3)ncnc21 +CCOc1ccc(C(=O)N2CC(c3nc(C)no3)C2)cc1OCC +Cc1ccccc1CN(C)C(=O)COc1ccccc1C(N)=O +O=c1cc(-c2cccc(O)c2)oc2ccc(O)cc12 +COc1cc(S(=O)(=O)NC2CCCC2)ccc1-n1cnnn1 +Cc1cc(NC(=O)c2ccc(Br)cc2C)n(C)n1 +CCOCC1CCN(C(=O)Cc2c(CC)noc2CC)C1 +Cc1cccc(Cn2cnc3c(NS(C)(=O)=O)c(C)c(C)cc32)c1 +COC(=O)c1ccc(NC(=O)NCc2nncn2C2CC2)cc1 +c1ccc(CCn2nc(C3CCCC3)nc2-c2ccon2)cc1 +CCOC(=O)CNS(=O)(=O)Cc1ccc(Cl)cc1 +OC(CN1CCOCC1)c1ccc(-c2ccccc2)cc1 +CCCNC(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1 +Cc1ccc(-c2cc(C#N)nn2CCCC(N)=O)cc1 +COC(=O)C(C)NC(=O)Cc1cn(C)c2ccccc12 +Fc1ccc(CN2CCCC(c3n[nH]c4nccnc34)C2)c(F)c1 +CCOC(=O)CN1CCN(c2cc(-n3cc(C)cn3)ncn2)CC1 +COCCc1noc(CN(C)Cc2cc3ccccc3s2)n1 +NC(=O)CCN(Cc1ccccc1)C(=O)NCc1cccnc1 +O=C(NC1Cc2ccccc2C1)C1(n2cnnn2)CCCCC1 +Cn1nc(C(=O)NCC2(c3ccccc3)CCC2)c2ccccc2c1=O +CCC(C)N(Cc1ccc(C)cc1)C(=O)c1cc(C)n[nH]1 +COCCn1nc(C(=O)NCCCO)ccc1=O +COc1cccc2c(C3N4CC5(C)CN3CC(C)(C4)C5)c[nH]c12 +CC1CCCN(C(=O)c2cc(S(N)(=O)=O)ccc2Cl)CC1 +Cc1noc(C)c1Cn1nc(C#N)cc1-c1cccs1 +Cc1cc(NC(=O)CCc2nc(C(C)(C)C)no2)c2ncccc2c1 +Cc1ccc(S(=O)(=O)C(C)C(N)c2cccs2)cc1 +COc1cccc(C(=O)Nc2ccc3oc(-c4ccncc4)nc3c2)c1 +Cc1sc(NC(=O)c2cc3ccccc3c(=O)o2)c(C(N)=O)c1C +CC(=O)NC(C)(C)c1noc(CNc2ccc(C#N)cc2)n1 +CNC(=O)COC(=O)c1ccc(-c2ccccc2)cc1 +COC(=O)CNC(=O)C1CC(=O)N(c2cccc3ccccc23)C1 +Cn1cnnc1SCC(=O)Nc1ccccc1SCC#N +Cc1nnc(SC2CCCCNC2=O)n1-c1ccccc1 +COc1ncnc2c1CCN(C(=O)NC(C)C)C2 +CC(C)(C)c1nnc2sc(-c3ccccc3N)nn2c1=O +CCC1c2ccsc2CCN1C(=O)CNC(=O)c1cc(C)oc1C +CC1CN(C(C)C(=O)Nc2ccccc2N2CCCC2=O)CC(C)O1 +Cc1cc(C)c(C(=O)Nc2ccc(C(N)=O)cc2)c(C)c1 +CCC(NC(=O)C(C)OC1CCCCCC1)c1noc(C)n1 +COC(=O)c1cncc(N2CCN(c3ccccc3)CC2)n1 +Cc1cccc(CNC(=O)c2cccc(F)c2F)c1 +CSc1nnc(C2CCN(C(=O)N3CCOCC3)CC2)n1C +COc1cc(C(C)NC2CCN(C(C)C)C2=O)ccc1SC +COc1ccc(C(C)NC(=O)NCCc2cnn(C)c2)cc1OC +CCN(CC(=O)OC)C(=O)c1c[nH]c(=O)[nH]c1=O +CCC(CC)N(CCO)c1ccc(S(C)(=O)=O)cc1 +O=C(NCCCOCC(F)(F)F)Nc1ccccn1 +CC(C)C(C)NC(=O)CSc1nnc(C(C)(C)C)n1N +CCC(=O)NCC(=O)NC(c1ccccn1)c1ccccc1OC +Cc1ncnc(-c2ccc3c(c2)N(C)C(=O)C(C)O3)c1N +NC(=O)COc1ccccc1C(=O)NC1C2CC3CC(C2)CC1C3 +COc1ccc(CCNC(=O)c2cc3c([nH]c2=O)CCCC3=O)cc1 +CC(NC(=O)c1ccoc1)C(=O)OCc1ccc(Cl)cc1Cl +CCOC(=O)N1CCN(C(=O)Nc2ccncc2)CC1 +CCC(=O)Nc1ccc(O)c(C(=O)NCc2nc3ccccc3[nH]2)c1 +c1ccc2c(c1)CCCN2CCN1CCCC2(C1)OCCO2 +CCc1cc2c(=O)n(CC(=O)c3ccc(Cl)cc3)cnc2s1 +COc1ccc(CNCCc2ccc(-n3cccn3)cc2)cc1F +COc1ccccc1-c1nc2cc(CO)ccn2c1N +CNC(=O)c1cc2c(nc1N(C)C)CCN(S(C)(=O)=O)CC2 +NC(=O)C1CCN(C(=O)C2(c3cccc(F)c3)CCOCC2)C1 +CCC(C#N)CCC(=O)N1CCN(C(C)=O)CC1 +Cc1noc(C)c1CC(=O)Nc1ccc2c(c1)OCCO2 +O=C(CCNS(=O)(=O)c1ccccc1F)NC1CCC(O)CC1 +CCn1cc(S(=O)(=O)NCCC(C)n2nc(C)cc2C)c(C)n1 +CC(=O)NCc1ccc(-c2csc(CC(=O)N(C)C)n2)o1 +CCOc1ncccc1C(=O)NC1COCC1Cc1cc(C)no1 +COc1ccc(C(=O)Nc2cccc(C(N)=O)c2)c(OC)c1 +CC(C)CN(CC(C)C)C(=O)CCn1cnc2sccc2c1=O +CCCS(=O)(=O)NCC#CCOc1ccccc1Cl +Cc1ccc(N)c2c1S(=O)(=O)c1ccccc1C2 +Cn1cc(CC2C(O)CCN2C(=O)C2CCC2)cn1 +CCN(CC(=O)OC)S(=O)(=O)c1ccc(C)s1 +O=C(c1cnc(C2CCCO2)s1)N1CCCC1C1CCCC1 +CC(CO)NC(=O)Cc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CCn1ccnc1S(=O)(=O)C(C)c1cn(-c2ccccc2)nn1 +CC1Cc2cc(CNC(=O)c3cnc(-c4cccnc4)nc3)ccc2O1 +Cc1nc2ccc(NC(=O)CCn3cnc4ccccc43)cc2s1 +CCN1C(=O)Cc2cc(C(O)Cc3ccccc3)ccc21 +Cn1cnnc1C1CCCN(C(=O)Cc2cccc(OCC#N)c2)C1 +O=C(CN1CCc2ccccc21)NCc1ccco1 +CC(C)(CN1CCOCC1)NS(=O)(=O)c1ccc(Cl)cc1 +c1nc(N2CCCC(Cn3cncn3)C2)c2cc[nH]c2n1 +O=C(Cc1ccc2c(c1)CCCC2)Nc1ccccc1N1CCCC1=O +COCCN(Cc1ccco1)Cc1cc(F)cc2cccnc12 +CCC(=O)N1CCCCC1C(=O)NCc1cccc(NC(C)C)c1 +Cc1ccc(Cl)cc1-c1cn2cc(CO)ccc2n1 +CC1CN(Cc2ccccc2)CCN1C(=O)c1cccc(C#N)c1 +Cc1nn2c(N)c(C(=O)N3CCOCC3)cnc2c1-c1ccccc1 +O=C(c1cc2ccoc2cn1)N1CCCN(C(=O)C2CCC2)CC1 +NC(=O)c1cnc(NC(=O)C2CC2c2ccc(F)cc2)s1 +Cc1ccc(-c2nc(CC(=O)NC3CCCC3)no2)cc1 +CCOc1ccc2ccccc2c1C(=O)Nc1ncc(C#N)s1 +CCc1onc(C)c1NC(=O)c1cn(C)nc1-c1ccc(F)cc1F +CC(c1ccncc1)N(C)C(=O)c1ccc(Br)cc1 +CC1CCCN(C(=O)C2CC(C)Nc3ccccc32)C1 +CNC(=O)C(C)Nc1nc2cc(Br)ccc2s1 +CC(Sc1ccccc1N)C(=O)N1CCc2ccccc21 +C#CCN1CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +O=C1CCCN1CCCNc1ncc(F)c(N2CCOCC2)n1 +COCCNC(=O)NC(C)C12CC3CC(CC(C3)C1)C2 +CC(O)C(NC(=O)c1cc(COc2ccccc2F)[nH]n1)C(N)=O +CN(C)S(=O)(=O)N1CCC(C(=O)NC2CC3CCC2C3)CC1 +COc1ccc(CN(C)c2c(C#N)nnc3ccccc23)cc1 +O=C(NCC1(c2ccc(F)cc2F)CC1)c1ccco1 +C#CCOc1ccc(C2Nc3ccccc3C(=O)N2C2CC2)cc1 +CC(=O)Nc1ccc(F)c(C(=O)NC(C)C2CCCCC2)c1 +COCCCOc1ccc(C(=O)N=c2[nH]nc3cc(C)ccn23)cc1 +CCN(CC1COc2ccccc2O1)C(=O)c1cc[nH]n1 +CC(=O)N(C)c1cccc(NC(=O)N2CCOCC2C2CC2)c1 +Cc1ccc(C(=O)Nc2cc(S(=O)(=O)N(C)C)ccc2F)s1 +CCn1c(=O)n(CC(=O)N2CCCN(C(C)=O)CC2)c2ccccc21 +CCOc1ncccc1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12 +Cc1ccc(S(=O)(=O)Nc2cccc(S(C)(=O)=O)c2)cc1 +COCCNC(=O)NCCc1ccc(F)c(Br)c1 +CNC(=O)c1ccccc1C#CCNC(=O)c1cnc2ccccc2n1 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+CCOC(=O)C1CCCN(c2cc(Cl)c3cc[nH]c3n2)C1 +CC(C)(C)OC(=O)N1CCC(Oc2ccnc(C#N)c2)C1 +CCOCCn1c(-n2nc(C)cc2N)nc2ccccc21 +NC(=O)c1ccc(C(=O)N2CCCCC2Cn2cccn2)s1 +COc1ccc(F)cc1NC(=O)N1CCCC(N2CCCC2=O)C1 +CCS(=O)(=O)NCC(=O)c1ccccc1OC +COC1CCN(S(=O)(=O)c2cc(C)c(Cl)cc2Cl)CC1 +CC(C)(C#N)NC(=O)c1ccc(NC(=O)C2CC2)cc1 +Cc1cc(NC(=O)c2csc(-c3cnccn3)n2)c2ccccc2n1 +CC(NC(=O)NC(C)C(=O)N1CCCCC1)C(=O)N1CCCCC1 +CC1CN(C(=O)CCn2ccc(=O)[nH]c2=O)CC1(C)O +CCCCCN(C)C(=O)c1[nH]nc(C2CC2)c1N +O=C(c1ccnc(-n2cnnc2)c1)N1CCC(c2cccc(O)c2)CC1 +CCC(=O)NCCNc1cc(-n2ccnc2C)ncn1 +Cc1nc(CNC(=O)C(C)Oc2ccc(-c3ccccc3)cc2)no1 +COC(C)(C)c1noc(-c2cccc3[nH]ccc23)n1 +Cc1ncsc1-c1nnc(CNC(=O)CC2CCCCC2)o1 +CNC(=O)C(C)OC(=O)c1cccnc1Oc1ccccc1 +CCCn1c(=O)c(C)nc2cc(-c3noc(-c4ccccn4)n3)ccc21 +Cc1nc2cc(C3CCCN3C(=O)C(C)(C)C)nn2c(O)c1C +Cc1nn(-c2ccccc2F)c2c1C(=O)CC(C)C2 +CC(=O)Nc1cccc(NC(=O)Cc2coc3cc4c(cc23)CCC4)c1 +O=C(NCCc1ccco1)c1cccc(Cl)c1Cl +CN(CCc1ccccn1)c1nnc(C(C)(C)C)o1 +N#Cc1ccc(N2CCCC2c2cccs2)nc1 +Clc1cc2c(cc1Cc1nc(C3CC3)n[nH]1)OCCO2 +Cc1cc(C(=O)Nc2cccc(COCC(F)(F)C(F)F)c2)on1 +Cc1cc(NC(=O)CSc2nnc(-c3ccccc3F)n2C)no1 +CC(=O)Nc1ccc(F)c(C(=O)OCc2cncs2)c1 +COC(=O)c1cc(CN2CCNC(=O)C2(C)C)c[nH]1 +Cc1cc(NC(=O)NCCc2cn3ccccc3n2)c2ncccc2c1 +Cc1ccc(OC(=O)c2cc(C(N)=O)cs2)cc1 +CCCC(C)NS(=O)(=O)c1ccc(C#N)cc1 +O=C1OCCC1Sc1nnnn1-c1cccc(F)c1 +COc1ccc(-n2nnc(CO)c2C2CCCO2)cc1Cl +NC(=O)Cn1cc(C(=O)N2CCC(=Cc3ccccc3)CC2)nn1 +CCN(C(=O)COCC(F)(F)F)c1ccc(F)c(F)c1 +Cc1c(C(=O)OC2CC3CC(C2C)C3(C)C)cnn1C +CCc1cc(C(=O)NC(C)c2ccc(OC(C)C)cc2)[nH]n1 +CCN(CC)C(=O)CS(=O)(=O)c1nnc(N2CCCC2)s1 +Cc1cc(NC(=O)NCCc2nc[nH]n2)c2ncccc2c1 +CC1CCCC(C)N1C(=O)c1cnc(C2CC2)nc1N +CNC(=O)Cc1noc(-c2ccc3ccccc3n2)n1 +CC(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)NC1(C#N)CCCCC1 +CNC(=O)c1cc2c(=O)n3cccc(C)c3nc2n1Cc1ccccc1 +Cc1cccc(N2CCN(C(=O)c3cnc4ncnn4c3C)CC2)c1 +COC(=O)C1CN(c2cc(C)ccc2OC)CCC1=O +Cc1cc(C)cc(NC(C)C(=O)Nc2c(C)nn(C)c2C)c1 +COCCN1C(=O)Cc2ccccc2C1C(=O)NCc1ccccc1 +CC(C)C(O)C1NCCc2ccc(-c3ccccn3)cc21 +Cc1n[nH]c(C)c1NS(=O)(=O)c1ccc(C#N)cc1F +COCCN(Cc1ccco1)S(=O)(=O)c1cc(C)ccc1F +CCC1(CC)Oc2ccc(N)cc2N(CC(O)CO)C1=O +Cc1nccc(C2CC3CCN(C(=O)c4cccs4)CC3O2)n1 +C#CCNC(=O)CN1CCc2cc(Br)ccc21 +CCN(C)C(=O)C(C)NS(=O)(=O)c1cnn(C)c1 +COc1ccc(OC)c(CN(C)C(=O)C2CCCCC2)c1 +CN(CC1COc2ccccc2O1)C(=O)C1CCCC1 +COc1cc(S(=O)(=O)N2CCCCC2)c(OC)cc1C +COc1cc(C2CC(=O)Nc3c2cnn3C)cc2c1OCO2 +CCCNC(=O)CC(C#N)c1ccccc1Cl +Cc1cc(C)n2nc(C)c(C(=O)NCCC(=O)N3CCCCC3)c2n1 +COCC(=O)NCC1(c2ccc(Cl)cc2)CCOCC1 +CC(C)COC(=O)C1CCCN1C(=O)c1ccccc1OC(F)F +COc1ccc(C(=O)NC2(C)Cc3ccccc3C2)cc1OC +CC(=O)NCC(=O)N1CCC(c2nc(C3CCCC3)no2)C1 +CC1Nc2cc(F)ccc2N(C(C)C(N)=O)C1=O +CS(=O)(=O)Nc1cccc(NS(C)(=O)=O)c1 +CN(C)S(=O)(=O)c1ccc(OCC(=O)NC2CC2)cc1 +CCCc1cc(=O)[nH]c(SCC(=O)Nc2nnc(C)s2)n1 +CC(=O)c1ccc(OCC(=O)NCC(C)C)cc1F +CC(C)n1cnnc1CN(C)c1ncnc2[nH]ccc12 +C#CCNC(=O)c1cccc(S(=O)(=O)N(CC)c2ccccc2)c1 +CCOc1ccccc1-n1nnc(C(=O)NCC2CCCO2)c1C +CCn1nnc2cc(C(=O)NCc3cccnc3)ccc21 +N#CCOc1ccc(Cc2nc(-c3ccncc3)no2)cc1 +Cc1ccc(C)c(C(=O)N2CCN(C(C)C(=O)N3CCCC3)CC2)c1 +Cc1cc(C(=O)Nc2ccc(N3CCNC(=O)C3)nc2)no1 +CCn1nc(-c2ccc(C)c(C)c2)cc(C(C)=O)c1=O +COC(=O)c1ccccc1NC(=O)Cn1ncccc1=O +CC(=O)N1CCCC(Cc2nccnc2Cc2ccc(C)cc2)C1 +CCn1ncc(N)c1C(=O)NCc1c(C)nn(C)c1C +CNc1nc(CNc2ncnc3c2oc2ccccc23)cs1 +COc1cc(-c2c(CO)nnn2C(C)C)cc(OC)c1OC +Cc1cccc(-n2nc(CC(C)C)nc2Cc2n[nH]c(=O)[nH]2)c1 +COc1cccc(C(=O)NCCc2nnc3ccccn23)c1F +CCCC1CN(C(=O)c2ccccc2OCCOC)CCO1 +CCOCCCNC(=O)c1cnc(N2CCCC2)nc1 +Cc1ccnc(-n2nccc2NC(=O)c2ccc(-n3ccnn3)cc2)c1 +COc1ccc(OCC(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +COCCn1c(SCC(=O)N2CCCC2)nnc1-c1ccco1 +Cc1ccn2c(=O)c(C(=O)NC3(C#N)CCCC3)cnc2c1 +N#Cc1nnn(-c2cc(Cl)cc(Cl)c2)c1-c1ccncc1 +CCSc1nnc(-c2cn(C)nc2OC)n1CCOC +CC(Cc1c(F)cccc1F)NC(=O)Nc1cnn(CC(N)=O)c1 +Cc1cccc(-c2nc3c(c(SCC(N)=O)n2)CCCC3)c1 +Cc1ccc(-c2cc(CNC(=O)c3ccc(=O)[nH]c3)no2)cc1 +CC(NC(=O)c1n[nH]cc1N)c1ccccc1Cl +CCCCC(=O)Nc1c(C)nc2sccn2c1=O +C=CCn1cnnc1SC(C)C(=O)Nc1ccc(C(N)=O)cc1 +O=C(c1cn2ccsc2n1)N1CCC(n2cnnc2)CC1 +O=C(CC1c2ccccc2CCc2ccccc21)NCc1ccncn1 +CC(O)(CNC(=O)c1cccc(-n2cncn2)c1)c1ccsc1 +O=C(NC=Cc1ccco1)Nc1ccc(F)cc1F +CCn1ncc(CNC(=O)c2nc3ncccn3n2)c1C +CC(Nc1c(C#N)c(=O)n(C)c(=O)n1C)c1ccc2c(c1)OCO2 +O=C(Nc1cnn(-c2ccccc2F)c1)c1ccc(-n2ccnc2)nc1 +CCOc1cc(N)cnc1Oc1ccc(C(=O)OC)cc1 +COCC(=O)Nc1cccc(Cn2cnc3ccccc32)c1 +CNC(=O)Cc1ccc(OCc2c(C)noc2C)cc1 +Cc1cccc(CC(=O)N(C)C(C)c2cccnc2)c1 +CCCCCCNC(=O)c1cnn(-c2ccncc2)c1C +COc1c(C)cccc1C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +COc1ccc(CNC(=O)Nc2ccccc2C)cc1 +CCC(C)Nc1ncnc(Nc2cccc(C)n2)c1N +CC(N)C(=O)OCc1ccc2c(c1)oc(=O)n2C +CC(NC(=O)C(C)Sc1nncs1)C(=O)NC(C)(C)C +CC(NC(=O)CCOCc1ccccc1)c1ccncc1 +COc1ccc(C(C#N)NC(=O)c2ccc(C)cc2)cc1 +CN(C)S(=O)(=O)c1ccc(C(=O)OCCc2ccccc2)cc1 +Cn1nc(CC(=O)NCC2CCOCC2)c2ccccc2c1=O +CC(C)c1cccc(NS(=O)(=O)c2cnn(C)c2)c1 +Cc1ccccc1C1(O)CCN(C(=O)c2cccc3ccnn23)C1 +COCCn1nc(-c2cccc(OC)c2)cc(CC#N)c1=O +CC(=O)N1CCc2cc(NC(=O)c3cc4ccccc4c(=O)[nH]3)ccc21 +Cc1ccc(C(=O)N2CCCC(c3n[nH]c(C4CC4)n3)C2)s1 +Cc1cccc(C(=O)N2CC(C)NCC2c2ccccc2)c1 +COc1ccc(NC(=O)C(C)Oc2cccc(Cl)c2)cc1OC +O=C(COc1nncc2ccccc12)NCCC1=CCCCC1 +C#CCn1nc(CO)cc1-c1ccc(C(C)(C)C)cc1 +CCc1ccccc1OCC(=O)C(C#N)c1nc(C)cs1 +COC(=O)c1ccc(Cn2cc(C(F)(F)F)ccc2=O)c(OC)c1 +COc1ccc(-c2nnnn2-c2cc(C)cc(C)c2)cc1N +Cc1ccccc1-c1cc(NC(=O)c2cccnc2)n(C)n1 +O=C(NCCc1cc2ccccc2[nH]1)c1cccnc1OCC(F)F +CCCc1nc(CNc2ccccc2C(=O)N2CCOCC2)cs1 +CN1CCOC2CN(C(=O)NCC(C)(C)c3ccncc3)CC21 +Cc1cc(Br)c(C)c2c1OCCC(=O)N2C +COCCN1CCN(Cc2nc(-c3ccc(F)cc3)no2)CC1=O +COc1ccccc1C(C)CC(=O)NC(C)c1c(C)noc1C +CCn1ccc(C(=O)N2CCCC2c2ccccc2C)n1 +C=C(C)CN(CC)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +Cc1cccnc1NC(=O)c1ccc(CNC(=O)C2CCCC2)cc1 +Nc1ccc(Cl)c2c(C(=O)NCc3ccco3)nccc12 +CNS(=O)(=O)c1cc(C(=O)NC(C)Cn2cccn2)n(C)c1 +CS(=O)(=O)c1ccccc1NC(=O)Cc1c(F)cccc1Cl +CCc1nc(COC(=O)C(NC(C)=O)C(C)C)cs1 +NC(=O)CCSc1ncc(C(F)(F)F)cc1Cl +Cc1ccc(S(C)(=O)=O)cc1S(=O)(=O)Oc1cccc(F)c1 +CC(=O)N1CCc2cc(S(=O)(=O)Nc3ccc(F)cc3)ccc21 +CC(C)CCN(CCC(C)C)C(=O)c1nonc1N +COC(=O)N1CCC(CNC(=O)c2cccc(OC)c2OC)CC1 +CN(Cc1cnn(C)c1)C(=O)CCNC(=O)OC(C)(C)C +CS(=O)(=O)c1ccc(CCn2cc(N)cn2)cc1 +OC(c1ccccc1)(c1ccccc1)c1cc[nH]n1 +CN(CCNC(=O)c1cc2ccccc2oc1=O)c1ccccc1 +O=C(NC1CCCN(c2ccccc2F)C1=O)c1cnccn1 +COc1ccc2c(=O)n(C(C)C(=O)N3CCCC3)ccc2c1OC +C=CCOc1cccc(NC(=O)N2CCCC2C(N)=O)c1 +Cc1nnc(-c2cccc(NC(=O)c3ccc(-n4ccnn4)cc3)c2)o1 +CC(C)Cc1ccc(C(O)CN2CCN(CCO)CC2)cc1 +COC(=O)C1CCCCN1Cc1cnn(-c2ccccc2)c1 +O=C(CNC(=O)Nc1cc(-c2ccccc2)on1)Nc1cccnc1 +Cc1ccc2ncc(C(=O)N(C)C(C)Cc3ccsc3)n2c1 +Cc1cccc2sc(NC(=O)c3ccccc3OCC(N)=O)nc12 +COc1ccc(CNC(=O)c2ccc(=O)oc2)cc1OC +Cc1cccc(-c2nc3cc4c(cc3[nH]2)OCCO4)c1 +COc1cc[nH]c(=NS(=O)(=O)c2ccc(C#N)cc2F)c1 +Cc1nnc(CCCNc2ccc3nc(C(C)C)sc3c2)o1 +COc1cccc(-c2nnc(NC(=O)c3cccc(SC)c3)o2)c1 +Cc1nc(CN2CC(Oc3cccnc3)C3OCCCC32)cs1 +O=C(c1cnc(Cc2ccccc2)s1)N(Cc1ccncc1)C1CC1 +CCC1CCCN(C(=O)c2cnn3c(-c4ccccc4)ccnc23)C1 +COC(=O)CC1CN(Cc2cc(Cl)ccc2F)CCO1 +Cc1ccc(CNC(=O)Nc2cccc(NC(=O)c3ccoc3)c2)cc1 +Cc1cc(NC(=O)Nc2cn[nH]c2)ccc1-n1cnnn1 +O=C(c1cc[nH]n1)N1CCOC2(CCCN(c3cccnc3)C2)C1 +CCNC(=O)N1CCN(CC(=O)NC(C)c2ccc(F)cc2)CC1 +Cc1nn(C(C)(C)C)c(C)c1S(=O)(=O)NCCc1cscn1 +CCCOc1ccc(-c2cc(-c3ccncc3)[nH]c(=O)c2C#N)cc1 +CCc1csc(C2CCCN(C(=O)c3ccc(=O)n(C)c3)C2)n1 +Cc1cnc(C(=O)N2CC3OCCN(CC4CC4)C3C2)cn1 +O=C(CNC(=O)OCC(F)(F)F)Nc1ccccc1-n1cccn1 +CC(=O)c1c[nH]c(C(=O)N(C)Cc2ccccc2N2CCCCC2)c1 +CC(C)C(NC(=O)NCc1nnc2ccccn12)c1ccccc1 +CN(C)C(=O)CCc1cccc(NC(=O)c2cccc(Cl)c2)c1 +NC(=O)c1ccccc1NC(=O)c1csc(-c2ccccc2)n1 +O=C(Nc1ncccc1CO)c1ccccc1Cl +CCC(C)n1ncc(C(=O)N2CCC(c3nc[nH]n3)CC2)c1C1CC1 +COCCNC(=O)C1(n2cnnn2)CCCCC1 +CC(NC(=O)c1cccc(N)c1)C12CC3CC(CC(C3)C1)C2 +CC(C)CN(C)C(=O)CNC(=O)COc1ccccc1 +CCC(=O)Nc1cccc(NC(=O)c2cccc3ccc(C)nc23)c1 +CCN(C(=O)c1cccnc1SC)c1ccccc1 +O=C(CN1CCN(C(=O)c2cnccn2)CC1)c1cccs1 +O=C(Nc1ccc(C(=O)N2CCCC2C2CCCC2)cc1)C1CC1 +CC(=O)NCCNCC(=O)c1ccc2c(c1)OCCO2 +CC1CCCC(CC(=O)Nc2nc3ccc(F)cn3n2)C1 +CC(=O)N1CCCN(C(=O)c2nc(-c3ccco3)sc2C)CC1 +Cc1nnc(CNC(Cc2ccc(F)cc2)C(C)C)s1 +CC(=O)Nc1cc(NC(=O)N2CCN(CC(C)(C)O)CC2)ccc1C +CCOC(=O)CCC1CCCN(C(=O)c2scnc2C2CC2)C1 +CC(=O)N1CCCN(C(=O)C(c2cccc(F)c2)N(C)C)CC1 +CN(C)c1ncnc2c1CCN(C(=O)c1ccco1)CC2 +Cc1nc(C(C)(C)NC(=O)CCC(C)C)sc1C +CC(Sc1nnnn1C1CC1)C(=O)NCc1ccccc1Cl +O=C(NCCNc1ncccn1)c1ccc(=O)[nH]c1 +O=C(CCNc1ncccn1)NCC1(c2ccccc2)CC1 +CSc1cccc(NC(=O)c2ccc(N)nn2)c1 +COc1ccc(C(=O)N2CCC(C)CC2C)c(O)c1 +CN(C)c1nnc(-c2cccc(Br)c2)o1 +COCCNC(=O)c1c[nH]c2ccc(Cl)cc2c1=O +NC(c1nc2c(s1)CCC2)c1ccccc1Br +CC(NC(=O)c1ccc2c(c1)OCCCO2)c1nnc2n1CCC2 +N#Cc1cn(C2CC2)c(=O)n(CC(O)COCc2ccccc2)c1=O +Cc1csc(CCC(=O)c2cccc(Br)c2)n1 +Cc1ccc(NC(=O)CN(C)C(=O)c2cccc(C#N)c2)nc1 +O=C1c2ccccc2NC(c2cccc(F)c2)N1Cc1cccnc1 +CC(=O)Nc1ccc(SCC(=O)Nc2cc(F)ccc2F)cc1 +COCC(C)N1CCN(C(=O)c2cnn(-c3ccccc3C)c2)CC1 +Cc1cc(CNC(=O)c2ccc(C(N)=O)nc2)no1 +COc1cc(-c2cn[nH]c2-c2ccccc2)cc(C#N)c1OC +Cc1cc(C(=O)NCC(=O)N(C)Cc2ccc(F)cc2)n(C)n1 +CCOc1c(Br)cc(CN(C)CC(F)F)cc1OC +Cc1ccnc2nc(C(=O)Nc3cccc4ncccc34)nn12 +Cc1ccc2ncc(C(=O)NCc3ccn(-c4ccccc4)n3)n2c1 +CCNC(=O)N1CCc2ccc(NC(=O)CCCn3cccc3)cc21 +CC(NC(=O)NC(CC(F)(F)F)c1ccc(F)cc1)C1CCOC1 +O=C(COC(=O)c1ccco1)c1ccc2c(c1)OCCO2 +O=C1CCC2(CCOC2)CN1Cc1cc(-c2ccco2)on1 +Cc1nccc(N2CCN(C(=O)NCC(C)Cn3cccn3)CC2)n1 +Cc1cc(Br)c2c(ccn2C(C)C)n1 +NC(=O)C1CCCN1S(=O)(=O)Cc1cccc(C(F)(F)F)c1 +CC1CCCCN1c1cc(Br)ccn1 +CN(C(=O)c1c[nH]nc1-c1ccccc1F)C1CC1 +CCCn1nc(C(=O)Nc2cccc(Cl)c2)ccc1=O +COc1ccc(CCCC(=O)N2CCC(=O)CC2)cc1 +CC(C)c1noc(CCCNC(=O)NC2CC(C)(C)OC2(C)C)n1 +CC(NC(=O)N1CCN(c2ncccn2)CC1)C1CCCO1 +O=C(CCCn1c(=O)oc2ccccc21)Nc1nccs1 +Cc1ccc(C)c(NC(=O)c2ccc3c(c2)NC(=O)CS3)c1 +Cc1csc(CNC(=O)Cn2ccc(=O)n(C)c2=O)n1 +CC(C)CC(=O)NCc1ccc(Oc2cccnc2)c(F)c1 +O=C(Nc1ccc2c(c1)C(O)=Nc1cccnc1O2)C1CCCO1 +COC(=O)C(C)c1c(C)nn(Cc2ccccc2)c1C +CCOC(=O)c1cccc(NC(=O)NCC2CCC2)c1 +CSc1ncnc(NCc2cn(C)nc2C)c1C#N +Nc1nc(C(=O)Nc2c(Cl)cc(Cl)cc2Cl)n[nH]1 +Cc1cnc(N)c(C(=O)C2CCN(C(=O)c3cnc(C)cn3)CC2)c1 +CC(Sc1ccccc1F)C(=O)NCc1ccccc1 +Cc1cccc(CN2CCN(C(=O)c3ccc4nonc4c3)CC2)c1 +CC1CC(c2ccccc2)C(C)N1C(=O)c1cccnc1 +NS(=O)(=O)c1ccc(NC(=O)OCCO)cc1 +CCOC(=O)c1cnc(SC)nc1N1Cc2cnc(CC)nc2C1 +Cn1cc(S(=O)(=O)NC(C)(C)CC(C)(C)C)cc1C(N)=O +CCN(Cc1ccccc1)C(=O)CSc1ncnc2ccccc12 +COc1ccccc1C(O)CCCC(=O)Nc1ccc(C)cc1 +O=C(Cn1cc(Cl)cn1)Nc1ccccc1N1CCCC1=O +O=C(NCc1cc(Cl)cc2c1OCC2)N(CCO)C1CC1 +O=C(Nc1nncn1Cc1ccccc1)c1ccnc(OC2CCC2)c1 +CC(C)Oc1c(Cl)cccc1NC(=O)N1CCOCC(O)C1 +Cc1ccc(S(=O)(=O)N(CCC#N)Cc2cccnc2)cc1 +O=C(CCc1ccc2[nH]ccc2c1)NCC1CCCO1 +CCCC(=O)NCC(=O)Nc1ccccc1OC(F)(F)F +COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1OC +NC(=O)c1cccc(CN2CCCc3cccc(F)c32)c1 +CCN1CCc2nc(NC(=O)COCC(F)(F)F)sc2C1 +CCCn1c(=NC(=O)CCn2cc(C)cn2)[nH]c2ccccc21 +CS(=O)(=O)NCc1cccc(CN2CCOCC2)c1 +Cc1nc(-c2ccc(NC(=O)c3cnoc3-c3ccco3)cc2)oc1C +O=C(Nc1ccc2c(c1)CCC2)NC1CCN(c2ccccc2)C1=O +COc1cccc(OC)c1C(=O)N1CCC(C)CC1 +Cc1ccnc(C(NC(=O)CC(O)c2cccc(F)c2)C2CC2)n1 +Cc1ccc(NC(=O)N(C)Cc2cc(C)on2)c(Br)c1 +N#Cc1ccc(NC(=O)C(Cc2ccccc2)n2cnnn2)cc1 +CSc1ccc(CNC(=O)NCCC(=O)NC2CCCC2)cc1 +Cc1cnn(CC2CCCN2C(=O)CCNc2ncccn2)c1 +Cc1nc(NC2CCCC2)c(N)c(OCC(C)C)n1 +COC(=O)c1cnc(NC(=O)C2Cc3ccccc3O2)s1 +CCOC(=O)Cn1c(-c2ccn(CC)n2)nc2ccccc21 +C=CCOc1c(CN2CCc3ccccc3CC2)c(C)nn1C +Cc1ccc(C)c(NC(=O)CNc2ccccc2C(=O)NC2CC2)c1 +CC(Sc1ccccc1)C(=O)OCCc1cccnc1 +CC(C)(C)c1nnc(SCCCC(=O)c2ccc(F)cc2)n1N +CCc1ccccc1NC(=O)N1CCOCC1C1CC1 +O=C(OCC(=O)N1CCCCC1)C1COc2ccccc2O1 +Cc1nc(Nc2ncccn2)cc(C2CN(C(=O)c3ccccc3)C2)n1 +CCc1cc(C(=O)OC)c(NC(=O)c2c(CC)noc2C)s1 +Nc1c[nH]c(=O)c(C(=O)Nc2ccccc2Cl)c1 +CCC(CC)C1CC(NC(=O)NCc2cscn2)CCO1 +Cc1ccc(O)c(C(=O)Nc2c(C)ccc(N)c2C)c1 +CCOC(=O)C(NC)c1nnc2c(N(C)C)cc(C)nn12 +O=C(NCCNC(=O)c1cccn2cncc12)c1cccc(Cl)c1 +CCOC(=O)C1CCCN(C(=O)c2cccc(S(C)(=O)=O)c2)C1 +O=C(OCCOc1ccccc1Cl)c1cc(=O)[nH]c2ccccc12 +COc1ccc(-c2noc(N)c2-c2ccccc2OC)cc1 +CC(=O)NCc1ccc(-c2csc(NC(=O)Cc3ccc[nH]3)n2)o1 +Cn1nc(C(=O)Nc2ccccc2F)c(=O)c2cc(F)ccc21 +Cc1c(C)n(C(=O)CSc2nnnn2C)c2ccccc12 +COCCOc1ccc(NC(=O)N2CC(C)CCC2C)c(C)c1 +CN(C)C(=O)c1ccnc(NCc2cnc3ccccn23)c1 +CCCCn1ncnc1-c1cnc2ccnn2c1C +Cc1noc(C)c1C(=O)N(CCc1ccccc1)Cc1cccs1 +Cc1n[nH]cc1CNc1ccc(S(=O)(=O)NC2CC2)cc1 +CC(=O)NC1C(CO)OC(n2cnc3c(N)ncnc32)C1O +CCOc1cc(NC(=O)NC2CCCn3nc(CC)nc32)ccc1C +CNC(=O)c1ccc(NC(=O)CCOCc2ccccc2)cc1 +CCOC(=O)Cn1nc(-c2ccncc2)nc1-c1ccncc1 +Cc1nc(Cn2nnc(-c3ccccc3C)n2)cs1 +Cc1ccccc1OCCNC(=O)CN(C)C(=O)c1ccccc1 +Cc1cccc(C)c1-n1nnnc1COc1ccccc1C(N)=O +O=S(=O)(Nc1nc2c(s1)CCCC2)c1ccccc1 +Cc1cc(C(=O)Cc2cccc3cccnc23)c(O)cc1O +Cc1noc(-c2cccn2Cc2ccc(F)cc2Cl)n1 +Cc1noc(C)c1C(=O)NCCNC(=O)OC(C)(C)C +OCc1nnn(-c2ccc3c(c2)OCO3)c1-c1cccnc1 +NC(=O)CCN(CCc1ccccc1)C(=O)c1ccco1 +CCOc1ccc(NC(=O)CSc2nc3ncccn3n2)cc1 +CC(c1cccs1)N(C)C(=O)CNC(=O)c1cccc(F)c1 +CC(=O)c1ccc(NC(=O)C(C)C2CCOCC2)cc1C +COc1ccc(OC)c(C(C)NC(=O)c2ccccc2)c1 +O=C(Nc1ccn(Cc2ccc(F)cc2)n1)c1ccncc1 +COC(=O)Cc1nc2c(C(F)(F)F)cccn2c1N +CC(C)CNC(=O)NCc1nc(-c2cccs2)no1 +COCCOc1ccccc1NC(=O)C1COc2ccc(F)cc2C1 +COC(=O)c1ccc2c(=O)[nH]c(C3CCCC3)nc2c1 +CC(NC(=O)C1CCCN(C(=O)C2CC2)C1)C(=O)N1CCCCC1 +NC1=NC(c2ccccc2)C2=C(N1)C(=O)N(Cc1ccccc1)C2 +CCN(CC)S(=O)(=O)CCNC(=O)c1cc2cccc(F)c2o1 +COc1ccc(OC)c(CCNC(=O)c2cnn[nH]2)c1 +Cc1n[nH]c(C)c1NC(=O)CN1CCCc2c(F)cccc21 +CCn1nc(C)cc1C(=O)Nc1nnc(-c2cccc(F)c2)o1 +O=C(COc1ccc(Br)cc1)Nc1ncccn1 +CC(C)N1CCN(S(=O)(=O)c2ccc3c(c2)CCO3)CC1 +CCCC(=O)NC1CCCN(c2cccc(F)c2C(C)=O)C1 +CCCCCC(C)NC(=O)Nc1cccc(C(N)=O)c1 +CC(NC(=O)NCc1ccnn1C)c1ccc2c(c1)CCCC2 +CC(C)CN1C(=O)C(=O)c2ccc(Br)cc21 +Cc1nnsc1C(=O)NCCn1ccnc1-c1ncccn1 +CCN(C)S(=O)(=O)NC(C)c1ccc(C)c(F)c1 +COc1cc(NC(=O)N2CCOC3(CCCC3)C2)c2ncccc2c1 +Cc1ccc(C(=O)N2CCCC(n3cccn3)C2)c(=O)n1C +OCc1ccnc(-c2ccc(OCc3ccccc3)nc2)c1 +CC(=O)NCC(=O)N1CCN(Cc2ccccn2)CC1 +Cc1c(C(=O)N(C)c2cccc3ncccc23)cnn1-c1ccccc1 +CN1CC(C(=O)N2CCN(C(=O)c3ccco3)CC2)CC1=O +CCCC(NC(N)=O)C(=O)N(C)Cc1ccccc1Br +CCOC(=O)Cc1nc(-c2ccc(OC)c(OC)c2)no1 +CC(Nc1ccccc1C(=O)N(C)C)c1cccs1 +COc1ccc(Cl)cc1CN(C)c1ncccc1C#N +c1ccc(CNCc2ccnc(OC3CCCC3)c2)nc1 +O=C(NCc1ccccn1)c1cnc2sccn2c1=O +CC(Sc1nnc(-c2ccc(C(C)(C)C)cc2)n1C)C(N)=O +CCOc1cc(F)ccc1NC(=O)c1cccnc1OC +O=C(Cc1ccc(F)cc1)NC1CCN(c2ccc(F)cc2)C1=O +COC(=O)c1c(C)[nH]c(C(=O)Cn2cnc(C3CCC3)cc2=O)c1C +COCCCOC(=O)Cn1cnc2c(C)cccc2c1=O +CCCc1cc(=O)c2ccc(C(F)(F)F)cc2[nH]1 +CN(Cc1ncno1)C(=O)c1cc2ccccc2s1 +COC(=O)C(C)CNc1ccccc1SC(F)F +Cc1ccccc1CC(=O)OCC(=O)Nc1ccc(F)cc1 +CN(C)S(=O)(=O)c1cccc(Cn2c(=O)oc3cccnc32)c1 +CCCCNC(=O)Nc1ccccc1-n1cncn1 +O=C(NCc1ccco1)c1ccccc1C(=O)c1cccs1 +Cc1cc(O)c2c(c1)C(C(=O)Cc1ccc(O)cc1)NCC2 +Cc1c(CN2CCc3cccc(Br)c3C2)cc(C#N)n1C +N#CC(NC(=O)Cc1cccs1)c1ccc2c(c1)OCO2 +Cc1ccc(CNc2ccc(CC(=O)N(C)C)cc2)s1 +COc1ccc(Br)cc1-c1oncc1C(C)=O +CCOc1cc(C#N)ccc1OC(=O)C(C)NC(=O)c1cccs1 +NS(=O)(=O)CCCNC(=O)c1ccc(Br)c(F)c1 +COc1ccccc1CC(=O)N(CC1CCOC1)C1CC1 +Cc1c(Br)cnn1C(C)C(=O)Nc1nccs1 +O=C(CCCS(=O)(=O)c1ccccc1)Nc1ccc(F)cc1F +O=C(c1sccc1-c1cccnc1)N1Cc2nn3nccnc3c2C1 +COc1nn(C)cc1C(=O)Nc1ccc(-n2nnc(C(N)=O)n2)cc1 +CC(C)(C#N)CCCS(=O)c1ccc(C(=O)N2CCCC2)cn1 +CCc1cc(C(C#N)CC(=O)N(C)C)ccc1OC +COn1c(-c2ccc(Cl)cc2)nc2ncccc21 +CCN(Cc1ccc(Cl)c(Cl)c1)S(=O)(=O)c1cn[nH]c1 +COc1ccccc1OCC(=O)Nc1ccc(O)cc1 +Cc1cc(C(=O)NCCc2ccc(O)cc2)c(C)s1 +CCOc1ccc(F)c(C(=O)NC(C(=O)OC)C(C)(C)C)c1F +COC(=O)c1cc(CN(C)C(=O)Nc2ccccc2)oc1C +CCn1cc(CCC(=O)NCc2ccccc2C(F)(F)F)c(C)n1 +Cc1ccc(C(=O)NCC(=O)NCc2cccs2)cc1C +O=C(NC1CCCCCC1)c1cccnc1-n1cncn1 +CCC1(NC(=O)Nc2cc(OC)ncn2)CCC1 +COc1ccc2cc(C(=O)N3CCn4c3nc3ccccc34)[nH]c2c1 +O=c1[nH]c2ccc(S(=O)(=O)N3CCCCCC3)cc2[nH]c1=O +Cc1cccc(C(C(=O)N2CCC3(CCO3)CC2)N(C)C)c1 +COc1cc(Cl)c2c(c1OC)CNCC21CCCC1 +Cc1ccc(C)c(SCC(=O)N2CCC(O)(C(F)(F)F)CC2)c1 +Cc1nc(CN2CCN(S(=O)(=O)Cc3ccon3)CC2)cs1 +CC1CCC(NC(=O)COc2ccc(F)c(F)c2)CC1 +CCCCc1nc(CN2CCN(c3ccc(O)cc3)CC2)no1 +O=C(NCc1cccc(Cn2cccn2)c1)NC(C1CC1)C1CC1 +CS(=O)(=O)NCCC(=O)NCC1CCN(c2ccccc2)C1 +CCn1c(N)nnc1SCC(=O)N1CCc2ccccc21 +CSc1ccc(OCCn2c(=O)oc3ccccc32)cc1 +O=C(Nc1ccc(-c2ccccc2)cn1)C1CCCN(C(=O)C2CC2)C1 +CC(C)OCCCNC(=O)c1cccc(-n2cccc2)c1 +O=C(Nc1c[nH]c2ccccc2c1=O)N1CCOCC1 +CCc1nc(C)c(C(=O)NCCCSc2nnc(C)s2)s1 +COC(=O)C(C)CNC(=O)Nc1ccc(SC(F)F)cc1 +CCN(CC)C(=O)CSc1nnc(-c2ccco2)n1N +CCN(CC)C(=O)N1CCC(C(=O)NCCOC)CC1 +Cc1ccc(-c2nc(CC(=O)N3CCCC3C(N)=O)cs2)cc1 +CNC(=O)c1ccc(Cl)c(S(=O)(=O)NC)c1 +CCC(C)(C)NC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +CCNC(=O)c1ccc(CNC(=O)N2CCCCCC2)cc1 +Oc1ccc(C(O)c2ccccc2F)cc1Cl +NC(=O)NCCC(=O)NCCc1cc(Cl)cc(Cl)c1 +CN(CCc1ccccc1)C(=O)NCCC(=O)N1CCCCC1 +O=C(Nc1ccc(F)cc1)NC1CCN(c2ccc(F)cc2)C1=O +Cc1c(CN(C)C(=O)c2nn(C)cc2Br)cnn1C +COc1ccc(S(=O)(=O)n2nc(-c3ccccc3)cc2N)cc1 +CCN(CC(=O)NC(C)C)C(=O)c1[nH]c(C)c(C(=O)OC)c1C +O=S(=O)(NC(c1ccccc1)c1ccccn1)c1cccc(F)c1 +Cc1c(Cl)cnn1Cc1nnc(-c2ccco2)o1 +Cn1c(=O)c(CNc2ccccc2)cc2ccccc21 +CCc1ccc(CNCC(O)c2ccccc2F)cc1 +CC(=O)NCCC(=O)NCc1ccc2c(c1)OCO2 +Nc1ccc2c(c1)N(C(=O)c1cc(F)cc(F)c1)CCS2 +O=C(NCCC(O)c1cccs1)C1CCCC1 +CCc1ncc(CN(C)c2ncccc2S(N)(=O)=O)s1 +CC(C)Oc1ccc(NC(=O)c2cnn(C)c2N)cc1 +Cc1ccc(C(O)CCNc2c(C)cccc2C)cc1 +Cc1noc2ncc(-c3nnc(Cc4ccc(F)cc4)o3)cc12 +Cc1cccc(OCCNC(=O)C2CCCCN2S(C)(=O)=O)c1 +CN(Cc1nc(-c2ccccc2)no1)C(=O)c1ccco1 +CCN(CCO)C(=O)C1CC(=O)N(c2ccc(SC)cc2)C1 +Nc1c(N2CCc3ccccc32)ncnc1-n1nnc2ccccc21 +CCCCNC(=O)CN1CCN(C(=O)c2cccs2)CC1 +Cc1nn2c(CNC(=O)Cc3ccc(F)cc3)c(C)nc2s1 +O=C(c1cccs1)N(Cc1cccnc1)C1CC1 +Cc1nc(C(C)(C)NC(=O)NC(C)Cc2ccc(O)cc2)sc1C +O=C(NCc1ccco1)C1(c2cc(-c3cccs3)on2)CC1 +Cc1ccc(CNc2cc(C)cc3cccnc23)nc1 +Cc1csc(CCNC(=O)COc2ccccc2)n1 +COC(=O)C(C)NS(=O)(=O)c1c(C)noc1C +NC(=O)C1CCN(C(=O)CCNC(=O)c2ccsc2)CC1 +C=C(C)Cn1nnc(-c2nc(-c3ccccc3)no2)c1N +Cc1ccc(-c2c(NCc3ccco3)c(=O)c2=O)cc1 +COC(=O)c1ccc(N2CCCC2)c(NC(=O)Nc2cn[nH]c2)c1 +CCOCCOCC(=O)NC1CCCc2ccccc21 +COc1ccc(-n2cc(CNC(=O)NC(C)C(C)CO)nn2)cc1 +O=C(c1cnc(NCCc2ccsc2)c(Cl)c1)N1CCCCC1 +CNc1nc(N(C)C)nc(-n2cnc(SCC(=O)OC)n2)n1 +Cc1cc(COC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)on1 +COc1ccc(C(C)NC(=O)Cc2csc(C)n2)cc1F +CCCOc1ccccc1C1NC(=O)NC(CC)=C1C(=O)OC +CC(C)N(Cc1cccnc1)S(=O)(=O)c1cccnc1 +O=C(Nc1ccc(-c2nccs2)cc1)N1CCC(O)C1 +Cc1cccc(OCc2c(CO)nnn2CCO)c1C +O=C1CCC(C(=O)N2CC3(CCCC3)c3c(F)cccc32)CN1 +COc1ccc(-c2cnc(Cn3cc(C)cn3)o2)cc1 +CCc1cccc(NC(=O)Cn2c(=O)cnc3ccccc32)c1 +COC(=O)c1cccc(Cn2cc(Br)ccc2=O)c1C#N +O=S(=O)(Nc1ccccc1CO)C1CCCCC1 +C=CCn1c(-c2ccncc2)nc2c(N)cccc21 +CNc1cc(-c2ccc(OC)c(OC)c2)nc(C)n1 +Cc1ccc(CN(C)C(=O)NCC2CC(=O)Nc3ccccc32)s1 +N#Cc1cccc(NC(=O)c2cncc(Br)c2)c1 +NC(=O)c1ccc(NC(=O)COc2nnc3ccccn23)cc1 +NC(=O)C1CCN(C(=O)c2csc3c2CCCC3)C1 +CC(=O)Nc1cc(NC(=O)c2cc(Cl)ccn2)ccc1F +Cc1oc2ccc(OCC(N)=O)cc2c1C(=O)OC(C)C +COc1cccc(NC(=O)CNc2ccc(NC(C)=O)cc2)c1 +Cc1c(C)c(C)c(S(=O)(=O)Nc2ccc(C(N)=O)cc2)c(C)c1C +COc1ccc(OC(C)C(=O)NC2CCCC2)cc1 +Cc1nc(N2CCNc3ccccc3C2)c2cnn(C)c2n1 +O=C(COC(=O)c1ccccn1)Nc1ccc(OC(F)(F)F)cc1 +CN(CC1COc2ccccc2O1)c1ncnc2ccccc12 +O=C(CSc1cccs1)Nc1ccc(F)cc1 +CC1(C)Nc2ccc(S(N)(=O)=O)cc2NC1=O +COCCn1cc(NC2CCC(C)CC2)ccc1=O +N#Cc1cc(F)cc(C2NCCc3c(F)cccc32)c1 +CNC(=O)c1cccc(NCc2cccc(F)c2)c1C +CC(=O)Nc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1 +N#Cc1ccc(Cn2nncc2-c2ccc(F)cc2)cc1 +CN(C)C(=O)C1CCN(C(=O)c2cccnc2)CC1 +CC(C)NC(=O)COc1ncnc2scc(-c3ccc(F)cc3)c12 +CCN(CC(=O)NCc1cccnc1OC)c1ccccc1 +CN(CC1CC1)C(=O)c1cccnc1Nc1cccc(F)c1 +N#CCSc1nc2nc(-c3ccccc3)cc(-c3cccnc3)n2n1 +Cn1nccc1NS(=O)(=O)c1cc(Cl)c(Cl)cc1Cl +CCN(C)C(C(=O)NC1CCOC(CC(C)C)C1)c1ccccc1 +CCSc1nc2nccc(-c3cccc(OC)c3)n2n1 +CNC(=O)C1CN(CCc2cccs2)CCO1 +O=C(NCCC1CNc2ccccc21)C1CCCC1 +CCCc1cc(C(=O)Nc2nc(C)c(C(=O)OCC)s2)cs1 +O=C(NCCCn1cnc2ccccc21)NCCc1ccccc1F +CN(Cc1csc(-c2ccccc2)n1)C(=O)c1cccnn1 +CC(C)(CNC(=O)NCc1ccc(-n2ccnc2)c(F)c1)C(N)=O +N#CC1C(=O)Nc2nc3ccccc3n2C1c1ccccc1 +COCCS(=O)(=O)NC(C)c1cccc(Br)c1 +O=C(NC1CCCCC1O)C1COc2ccccc2O1 +COc1cccc(NC(=O)COC(=O)c2ccco2)c1 +CC(C1CC1)N(C)C(=O)c1cn(-c2ccc(C(F)(F)F)cn2)nn1 +O=C(Cc1nc(-c2ccccc2)cs1)Nc1ccccc1 +COC(C)c1cccc(-c2nccnc2N(C)C)c1 +Cc1ccc(C2CCCN2S(=O)(=O)N(C)CCc2ccncc2)o1 +NC(=O)C1CCCC1NC(=O)c1c[nH]c2cccc(F)c12 +Cc1nnc(NC(=O)CN2CCN(CC(O)C3CC3)CC2)s1 +Cc1ccc(OC(=O)c2cnn(C(C)(C)C)c2)cc1 +CSc1nc2nc(C)c(CC(=O)OC3CCOC3=O)c(C)n2n1 +O=C1OC(C(=O)N2CCc3ccc(Cl)cc3C2)Cc2ccccc21 +COc1cc(NCc2ccc(C)o2)ccc1N1CCCC1=O +COc1cc(C(=O)N2CCC3(CC2)OCCO3)ccc1OC(F)F +Cc1ccc(OCC(=O)N(C)Cc2ccc(O)cc2)cc1C +OC(CSc1nnnn1Cc1ccco1)c1cccc(F)c1 +CC1OCCC1C(=O)Nc1cc2c(=O)[nH]cnc2cc1F +Cc1cc(-c2cccc3cccnc23)cn2nc(N)nc12 +Cc1noc(C)c1CN(C)S(=O)(=O)c1ccccc1C(F)(F)F +O=C(OCCN1CCCC1=O)c1cccc2ccccc12 +COc1c(C)cnc(CNS(=O)(=O)Cc2ccccc2C)c1C +COc1cccc(C(=O)NC2CCCCC2C(N)=O)c1F +CCc1ccc(C(=O)N2CCN(C(=O)COC)CC2)o1 +CNC(=O)c1coc(COc2ccc(C)cc2OC)n1 +O=C(C1CC1)N1CCn2cccc2C1c1ccccc1F +O=C(NCCc1ccccn1)c1cccc(C(F)(F)F)c1 +CCN(C(=O)CS(=O)(=O)c1nncn1C(C)C)C1CCCCC1 +CCN(Cc1ccc(C#N)cc1F)C(=O)Nc1cnn(CCOC)c1 +O=C(NCCCn1cccn1)c1cnn(-c2ccccc2)c1 +COc1ccc(C2=CCN(C(=O)C3CCCN(C(N)=O)C3)CC2)cc1 +O=c1oc2ccccc2n1Cc1nc(-c2ccco2)no1 +CN(Cc1ccccc1)C(=O)c1ccc(N2CCCOC2=O)cc1 +NC(C(=O)NCc1ccco1)c1ccc(F)cc1F +CCOCC(O)CN1CCN(c2ccccc2C#N)CC1 +O=C(CSc1nc2ccccc2[nH]c1=O)NCc1ccco1 +O=C(CCOc1cccc(Cl)c1)N1CCC(O)C1 +CC(=O)NCCCNS(=O)(=O)c1cccc(C(C)=O)c1 +O=C(Nc1c[nH]cc(Br)c1=O)C1CCC(F)(F)CC1 +CN1C(=O)N(c2cc(C3(C)CC3)on2)C(O)C1O +CN(Cc1cccc2cccnc12)c1cc(N2CCOCC2)ncn1 +CC(C)OCCCNC(=O)Nc1cccc(F)c1F +CCNC(=O)NC(c1cccnc1)c1cccc(C(F)(F)F)c1 +CNC(=O)C(C)NCc1ccc(OCc2cn3ccccc3n2)cc1 +COCCC(=O)NC1CC(=O)N(CCc2ccc(F)cc2)C1 +Cc1ccc2[nH]c3c(=O)n(CC(=O)Nc4ccccc4C)ncc3c2c1 +NS(=O)(=O)c1cnc(N2CCCCCC2)s1 +Cc1sc(C(=O)N2CCN(CCO)CC2)cc1-c1ccc(F)cc1 +Cc1cc(C(C)NC(=O)C2COc3ccc(F)cc3C2)c(C)o1 +Nc1ccc2nc(N3CCCCC3CO)cnc2c1 +Cc1ccc(NC(=O)CSc2nnc3[nH]c(=O)c(C)nn23)c(C)c1 +Cc1cccc(NC(C)C(=O)N2CCOCC2)c1C +CCC(C)NC(=O)NC(C)c1cc(C)sc1C +O=C(COc1ccc(F)cc1)NCc1csc(C2CC2)n1 +O=C(NCCc1ccccn1)c1coc(-c2ccccc2)n1 +COCCN(Cc1cnn(C)c1)C(=O)C(C)N1CCCC1=O +CNC(=O)NCC(=O)Nc1ccc(OC(C)(C)C)cc1 +CNC(=O)COc1cc(C(=O)NC2CC2)ccc1N +O=c1[nH]c2sc3c(c2c(=O)n1CCO)-c1ccccc1CC3 +CSc1ncc(Cl)c(C(=O)Nc2c(C)cccc2C)n1 +Cc1cc(NC(=O)C2CN(c3cncnc3)CCO2)[nH]n1 +Cc1cc(NC(=O)CNc2cccc(F)c2)n(C)n1 +CNCC1NCCc2c(OC(F)(F)F)cc(O)cc21 +CCN(CC(C)C#N)C(=O)C(C)Oc1ccc(C#N)cc1 +CCOc1ccc(C(=O)N(C)c2cccc3ncccc23)cn1 +CC(NC(=O)NCC(=O)NC1CC1)c1cccc(Cl)c1 +c1ccc(C(OCCSc2ncn[nH]2)c2ccccc2)cc1 +CC(C)(C)Cc1nnc(NCc2cccs2)o1 +Cc1cccc(C(=O)Nc2c(C)nc3sccn3c2=O)c1 +Cc1cnn(C2CCCN(C(=O)c3ccoc3C)C2)c1 +Cc1nc(C(=O)NCc2cc(F)cc(Br)c2)cs1 +COC(=O)CN(C)C(=O)c1nccc2c(N)ccc(Cl)c12 +C#CCNC(=O)c1c(C)c2cc(Br)ccc2oc1=O +OCc1nc2ccccc2n1CC(O)COc1ccc2c(c1)OCO2 +CCOCC(=O)N1c2ccccc2CC1C(=O)NC +CCCCC1C(=O)N(C)CCN1C(=O)Nc1cc(F)ccc1C +Cc1nc(COc2ccc(F)cc2Cl)sc1CO +CC(=O)N1CCCN(C(=O)Cc2coc3cc(C)c(C)cc23)CC1 +CCOc1ccc(C(C)NC(=O)N2CCCC(O)C2)cc1OC +CCN(Cc1cccc(NCc2nc(-c3ccco3)no2)c1)C(C)=O +C=CCSc1nc2ncc3c(n2n1)CC(C)CC3=O +CCC(=O)N1CCCC(C(=O)N(C)c2cccc3ncccc23)C1 +N#Cc1cccc(OCCCn2cnc(C3CCC3)cc2=O)c1 +COC(=O)C(CC(C)C)NC(=O)c1sc(C)nc1C +CN(Cc1cc(N)ccc1Cl)C(=O)c1cccs1 +O=C(Cc1cccnc1)N1CCC(Oc2ccccc2Cl)CC1 +O=C(NC1CC1)C(NCC1(c2ccc(F)cc2)CC1)c1ccccc1 +NC(=O)Nc1cccc(C(=O)N2CCOc3ccccc32)c1 +Cc1ccc(-c2nc(Cn3cnc4ccsc4c3=O)co2)cc1 +Cc1csc(CNC(=O)c2ccc(S(=O)(=O)C(C)C)cc2)n1 +COCC1CCN(C(=O)Nc2ccc(F)cc2OCC2CC2)CC1 +Cc1ccc2c(c1F)C(c1cccnc1N)NCC2 +Cc1csc(C(OC(=O)c2ccco2)C(F)(F)F)n1 +COCCNC(=O)c1c(C)noc1-c1ccc(C)cc1 +O=C(NCc1cc(F)cc(C(F)(F)F)c1)c1ccc2ccnn2c1 +COc1ccc2ccccc2c1C(=O)CN1CCOCC1 +Cc1ccc(Cl)c(OC(=O)c2cc3c([nH]c2=O)CCCC3=O)c1 +CCOC(=O)C1C(O)=Nc2nc3ccccc3n2C1c1ccccc1 +CN(C)c1ccc(NC(=O)CNC(=O)c2cccc(Cl)c2)cn1 +CCC(CC)NC(=O)C1CC(=O)N(CCc2ccccc2)C1 +CC(Oc1ccccc1)C(=O)N(C)CC(F)(F)F +CN(Cc1ccccn1)C(=O)Nc1ccc(-c2nccs2)cc1 +CNS(=O)(=O)c1ccc(Cl)c(C(=O)N2C(C)COCC2C)c1 +O=C(Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1)C1CCOCC1 +O=C(CCOCC1CCCO1)NCc1ccncc1 +CC(=O)Nc1ccc(C(=O)CSc2ccccc2C)cc1 +CCn1cc2c(n1)CN(Cc1c(C)noc1C)CC2COC +COc1ccc(CC(C)CNC(=O)c2nccnc2C(N)=O)cc1 +COCC(C)N1CCN(C(=O)C2(c3ccccc3F)CC2)CC1 +CC(C)CNC(=O)Nc1ccc(C(N)=O)cc1F +Cc1ccnc(C(=O)N2CCC3(CC2)CC(OCC2CC2)CO3)c1 +Cc1c(C(=O)N(C)CCC#N)cnn1-c1ccccn1 +Cc1ccc(C(=O)Nc2ccc(N)cc2C)cc1O +Clc1ccc(-c2n[nH]c(-c3cnccn3)n2)cc1 +C#CCOc1cccc(NC(=O)NCc2cnn(C)c2C)c1 +CN(CCCNC(=O)N1CCOCC1)c1ccccc1 +CC1C(=O)N(CCC(N)=O)c2cc(N)ccc2S1=O +C#CCN1CCN(C(=O)CNc2cccc(F)c2C)CC1 +Cc1ccc2nc(NC(=O)COC(=O)c3ccnn3C)sc2c1 +CCc1nnc2n1CCN(C(=O)COC1CCCC1)C2 +CCCC(C)(C)NC(=O)c1ccc(S(=O)(=O)NC)cc1 +Cc1ccc(N2CCN(CC(=O)NCCCO)C2=O)cc1 +CCOc1cccc(CNC(=O)c2noc(-c3ccc(C)cc3)n2)c1 +COc1ccccc1NC(=O)CCc1nc(-c2ccccc2)no1 +Cc1nc(CCN2C(=O)c3ccccc3S2(=O)=O)n(C(C)(C)C)n1 +CCCc1ccc(NC(=O)CNC(=O)c2ccncc2)cc1 +CCOC(=O)CN1CCC(c2nn(C)c(=O)n2-c2ccccc2)CC1 +CNc1cccc2c(OCc3cccnc3)nc(C)cc12 +COc1cccc(C(=O)n2nc(-c3ccccc3C)nc2N)c1 +CNc1nnc(SCC(=O)c2ccc(F)cc2)s1 +CCCNC(=O)c1nnn(-c2ccccc2)c1C(C)C +CC(=O)NCCCNC(=O)Nc1cc(Cl)ccc1Cl +Cc1cc(NCC2CN(C3CC3)CCO2)nc(-c2ccncc2)n1 +CC(C)C(=O)Nc1cccc(CNC(=O)c2cn(C)c3ccccc23)c1 +Cc1nccn1-c1ccc(C(C)NC(=O)CN(C)c2ccccc2)cc1 +COC(=O)c1c(C)[nH]c(C(=O)NCC2CCCCC2)c1C +O=C(Nc1ccc(Cl)cc1)C1CC(=O)N(Cc2ccccn2)C1 +CC1(C)CCC(CNC(=O)CCc2nc[nH]n2)CC1 +Cn1ncc2c(Nc3cnn(CC(N)=O)c3)ncnc21 +Cc1c(C(F)(F)F)n[nH]c1NC(=O)C(C)OCC1CC1 +COCCCNC(=O)Nc1cnn(-c2cccc(C(F)(F)F)c2)c1 +CCC(=O)NCC1CC(=O)N(c2ccc(OC)cc2)C1 +O=C(CCc1ccccn1)Nc1ccc(C(=O)C2CC2)cc1 +O=C(NCC1(c2cccc(Cl)c2)CCOCC1)c1ccc[nH]1 +Cc1occc1C(=O)Nc1nc(-c2c[nH]c(C(N)=O)c2)cs1 +COc1ccc(C2NC(=O)c3ccccc3O2)cc1OC +Cn1[nH]c(C2CN(c3cnccn3)CCO2)cc1=O +Cn1nnnc1-c1cccc(C(=O)NCc2ccc(Cl)cc2)c1 +O=C(Cc1ccc(-n2cccn2)cc1)NCCc1ccccn1 +Cc1ccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c(C)c1 +COc1cc(-n2nnnc2SC)c(Cl)cc1Cl +Cc1cccc(Cc2n[nH]c(CC(=O)NC3CCCCC3)n2)c1 +CC(C)(C)CCC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +Cn1c(CNc2cnn(-c3ccccc3)c2)nc2ccccc21 +CCOC(=O)c1cc(N)ccc1Sc1nc(C)n[nH]1 +Cc1nn(-c2nccs2)c2c1C(CC#N)CCC2 +Cc1cccc(C(=O)Nc2cc(C(=O)N3CCOCC3)ccc2C)c1 +COC(C)(C)c1noc(C2CC23CCCc2ccccc23)n1 +CCC(NC(=O)c1cn(C)nc1C(F)(F)F)c1ccc(OC)cc1 +Cc1ccc2nc(C)n(-c3ccc(F)cc3)c(=O)c2c1 +COc1ccc(CCC(=O)NCC2C(=O)N=C(C)C=C2C)cc1F +CCn1cc(NC(=O)N2CCN(C(=O)CCC(C)C)CC2)cn1 +CCOc1ncccc1NC(=O)N1CCC(CO)CC1 +CN(C)S(=O)(=O)N1CCN(C(=O)CCO)CC1 +CC(CCO)CNC(=O)Nc1ccc(-c2nccn2C(F)F)cc1 +Cc1ccc2c(c1)CCCN2C(=O)c1nc2nccc(C)n2n1 +Cc1cc(C)c(NC(=O)CCC(=O)c2ccc(F)cc2)c(C)c1 +CCCNC(=O)Nc1cccc(OCCn2cccn2)c1 +COCC(C)NC(=O)CSc1ccccc1Cl +CN1CC2(CCN(C(=O)c3ccccc3-c3ncc[nH]3)C2)OC1=O +Cc1csc2nc(CN3CCCSc4ccccc43)cc(=O)n12 +N#Cc1c(Br)cnc(N)c1Br +CCOc1ccc(C(=O)C(C#N)c2ccccn2)cc1OCC +COc1ncccc1CNC(=O)NCCC1CCCCC1 +Clc1cccc(Cl)c1CCNCc1c[nH]nc1-c1cccnc1 +Cc1nc(SCc2cn3ccccc3c2C#N)oc1C +Cc1ccc(CNS(=O)(=O)Cc2cccc(F)c2)c(N(C)C)c1 +CC(=O)N1CCN(CC(=O)Nc2sc(C)c(C)c2C#N)CC1 +Cc1cc(NC(C)c2ccccc2Cl)n2ncnc2n1 +Cc1ccc2c(c1)OCC(=O)N2CC(=O)Nc1ccc2cc[nH]c2c1 +Cc1cccc(C(=O)N2CCC(c3nc(C)cs3)CC2)c1 +COc1ccc(S(=O)(=O)N(C)C)cc1C(=O)NC1CCCC1 +CN(Cc1cnccn1)Cc1ccc(-c2cccc(Cl)c2)o1 +CC(NC(=O)C1CCCN(C(N)=O)C1)c1ccc2c(c1)OCCCO2 +CCCN(C)C(=O)c1cc(S(C)(=O)=O)ccc1C +O=C(Oc1ccccc1F)c1ccc2c(c1)OCCO2 +CS(=O)(=O)c1ccc2nc(NC(=O)C3CCCC3)sc2c1 +CS(=O)(=O)c1ccc(-c2ccc(Cn3ccnc3)cc2)cc1 +O=S(=O)(Cc1ccon1)c1nnc(NC2CCCCC2)s1 +O=C(Nc1ccccc1F)c1cccnc1OCC(F)F +Cc1occc1-c1nnc(CCC(=O)NCc2cccnc2)o1 +CNc1ccc(C)cc1C(=O)NC1CCCC1OC +O=S(=O)(CC1CCCCC1)Nc1ccccc1O +Cn1nccc1C(=O)NCCC(=O)Nc1nc(C(C)(C)C)cs1 +O=C(NC1CCCCC1)c1cccc(-n2cccc2)c1 +COc1cc(COC(=O)Nc2ccc(Cl)cc2)ccc1O +Cc1cc(C)c(NC(=O)NCC(C)CC(C)O)c(C)c1 +Cc1ccc(CNC(=O)c2cc3occc3n2-c2ccccc2)o1 +Cc1cc(-c2cccs2)c(C#N)c(N2CCCC2)n1 +CC(=O)N(C)C1CCN(C(=O)NC(C)C(=O)N2CCCCC2)CC1 +CCc1ccc(OC(C)C(=O)Nc2cccc(C(N)=O)c2)cc1 +COc1ccc(NC(=O)NC(C)c2cn(C)nc2C)c(OC)c1 +O=C(NCc1cc(F)ccc1Br)NC1CCCC1 +NC(=O)Cn1c2ccccc2c2nc3n(c(=O)c21)CCS3 +Cn1cccc1CN1CCc2c(nc(N3CCCCC3)[nH]c2=O)C1 +COC(=O)C(C)(C)CNC(=O)Nc1ccccc1-n1nc(C)nc1C +COc1cccc(CCC(=O)Nc2ccncc2)c1 +COC(=O)C1CN(c2c(C)cc(C)cc2C)CCC1=O +CCCOc1ccc(C(F)(F)F)cc1NC(=O)C1CCCO1 +O=C(CCc1ccccn1)N1CCc2cc(Br)ccc21 +Cc1cc(NC(=O)CN(C)C(=O)Cc2cccc3ccccc23)no1 +Cc1csc(C(C)N(C)C(=O)c2cc(C)nc3c(C)cccc23)n1 +Cc1cc(NC(=O)CCCn2cccc2)ccc1O +Cc1nn(C)c(Oc2cccnc2)c1CNc1cnn(CC(C)C)c1 +CCc1noc(CC)c1CNC(=O)NCc1ccc(OC)c(C)c1 +CN(CCc1ccc(F)cc1)C(=O)c1ccc2c(c1)OCO2 +CCc1cc(NC(=O)C2(c3ccccc3)CC2)[nH]n1 +Cc1cc(S(=O)(=O)NCC2CCCO2)c(C)cc1Br +COCc1nnc(NC(=O)Cn2nnc(C(C)=O)c2C)s1 +CCOc1ccc(F)c(C(=O)NCc2ccc3c(c2)OCO3)c1F +Oc1ccccc1N1CCN(CCOc2ccccc2)CC1 +CC(C)N(C)C(=O)NCC(c1cccc(Cl)c1)N1CCOCC1 +O=C(NCCOc1cccc(F)c1)c1cccnc1N1CCOCC1 +N#Cc1ccc(C(Sc2cccc(F)c2)C(N)=O)cc1 +CCNC(=O)c1cc(S(=O)(=O)NCc2ccccn2)ccc1OC +Cn1cc(CC2CCN(C(=O)C3CC3c3ccccc3Cl)C2)cn1 +CC(C)CCNC(=O)c1ccc(-n2cccn2)nc1 +CCn1nc(C(=O)NCCOC)c(=O)c2ccccc21 +COC1=CC(=O)OC1C(=O)c1ccc2c(c1)OCO2 +O=C(CCSc1cccc2cccnc12)N1CCOCC1 +COc1cccc(C(=O)CSc2ccccn2)c1 +CCCCn1c(SCC2CCCN(S(C)(=O)=O)C2)n[nH]c1=O +Cc1cc(NCc2nnc(-c3ccccc3)n2C)ccc1-n1cnnn1 +O=C(c1cccnc1-c1ccc(F)c(Cl)c1)N1CCCC1 +NC(=O)CN1CCN(Cc2cc(Cl)cc3c2OCC3)CC1 +N#Cc1nc(NC(CCO)c2ccccc2)ccc1Cl +C#CCCN1CCN(C(=O)c2c(F)cccc2NC(=O)C(C)C)CC1 +COc1cccc2c1CCN(C(=O)NCCc1ccncc1C)C2 +Cc1cccnc1NC(=O)c1onc(-c2ccccn2)c1N +CC(NC(=O)CN1CCOC(Cn2cncn2)C1)c1ccco1 +Cc1oc(-c2cccs2)nc1CC(=O)N1CCCC(O)C1 +CCNC(=O)C(C)NC(=O)c1[nH]nc(C)c1Br +Cc1nc(-c2ccccc2)nc2c1CCN(Cc1cnn(C)c1)CC2 +O=C(CCC1CCCCC1)NCc1ccc(-n2cncn2)nc1 +COC(=O)Cn1ccnc1Cc1ccc(F)c(F)c1 +Cc1[nH]ncc1S(=O)(=O)N=c1[nH]c(C(C)C)cs1 +CCC(=O)NCc1nc2ccccc2n1CC(=O)NC(C)CC +O=C1COc2ccc(-c3nnc(CCO)o3)cc2N1 +O=C1CC(c2cccc(F)c2)c2ccc(O)cc2N1 +N#CCCN1CCN(c2ncnc3sccc23)CC1 +CCn1c(C(C)NC(=O)C2CCC2)nc2ccccc21 +Cc1ccccc1CNC(=O)c1cc(C2CC2)nc2onc(C)c12 +Cc1ccc(-c2noc(CCC(=O)N(C)c3ccccc3)n2)cc1 +COCc1nc(C(=O)Nc2cccc(Cl)c2Cl)cs1 +CCOC(=O)N1CCC(NC(=O)Cc2ccccc2Cl)CC1 +Cc1noc(C)c1COc1ccc(C(=O)NCC(C)C)cc1 +O=C(CCn1ccc(=O)[nH]c1=O)Nc1ccc(-c2cc[nH]n2)cc1 +COc1ccccc1CNC(=O)CSc1nc(C)cc(C)n1 +CC(=O)Nc1ccc(NC(=O)Cc2csc(C)n2)cc1 +Cn1cc(NC(=O)Nc2ccccc2)cc(Br)c1=O +CSc1ncc(Cl)c(C(=O)N2CCN(CCO)CC2)n1 +Cc1csc(NC(=O)C2CN(c3ncnc4c3nnn4C)C2)n1 +O=C(NCCC(O)c1ccccc1)c1cc2ccccc2oc1=O +CC(C)Oc1ncnc(Nc2ccc(Cl)cc2)c1N +CN(C(=O)c1cnc(C2CCCO2)s1)c1ccc2c(c1)CCO2 +COc1ccc(C(=O)Nc2cc(C)n(C)n2)c(OC)c1 +Cn1cc(C(=O)NC(C)(C)C(N)=O)c2ccccc21 +Cc1occc1C(=O)NC1CCN(C(=O)CCc2ccccc2)CC1 +COc1ccc(-c2cc(C(=O)NCC(F)(F)F)[nH]n2)cc1 +Cc1nnc(NCCc2n[nH]c(-c3ccco3)n2)c(C#N)c1C +CCC(O)Cc1cccc(OCC(C)C)c1OC +CCN1CC(C(=O)N2CCOC3(CCCC3)C2)CC1=O +O=C(Cc1cccc2ccccc12)NCC(O)c1ccc2c(c1)CCO2 +C=CCN1CCN(C(=O)Cc2ccc(Br)cc2)CC1 +Cc1cccc(C(=O)Nc2cc(C(N)=O)ccc2N2CCCC2)c1C +CC(=O)Oc1ccc(CN2C(=O)c3ccccc3S2(=O)=O)cc1 +CCc1ncncc1C(=O)N1CCCN(c2nc(C)cs2)CC1 +O=C(c1ccco1)N1CCn2nc(-c3ccccc3)nc2C1 +C=C(C)Cn1c(C(=O)NCc2ccco2)cc2sccc21 +COc1ccccc1-c1nc(-c2ccc3nncn3c2)no1 +COCc1cc(=O)c2cc3c(cc2[nH]1)OCCCO3 +CN(C(=O)Cc1ccc(F)cc1F)c1ccc(S(C)(=O)=O)cc1 +CCN(Cc1ccc(OC)cc1)C(=O)c1cc(OC)c(C)c(OC)c1 +COc1cc(OC)c2c(c1)C(c1ccc(C#N)cc1)NCC2 +COc1ccc(-c2nc(CCNCc3ccncc3)co2)cc1 +OCc1ccc(NCc2cccc(F)c2Cl)cc1 +COc1ccc(C(CNCc2c(C)noc2C)N2CCOCC2)cc1 +COc1ccc(C(=O)NC2COC3C(OCC(N)=O)COC23)cc1 +O=C(Nc1nccs1)c1ccc(-c2noc(C3CCCC3)n2)cc1 +Cc1cccc(NC(=O)CSc2nnnn2C(C)C)n1 +Cn1ncc2c1CCCC2NC(=O)NCC1(c2ccccc2)CC1 +Nc1ccc(Cl)cc1NC(=O)CCCN1CCCC1=O +Cc1sc2ncnc(N(C)CC(=O)NC(C)(C)C)c2c1C +Cc1nc(SCCCN2CCCC2=O)c(C#N)c(C)c1C +CCCN1C(=O)CCC2CN(c3ncc(F)c(NC)n3)CCC21 +N#Cc1cc(N)cnc1Nc1cccc(Br)c1 +O=S(=O)(Cc1cn2ccccc2n1)c1ccccc1 +O=C(Cc1csc(-c2ccsc2)n1)Nc1ccc2c(c1)OCO2 +Cn1nc(C2CCN(CC(=O)OC(C)(C)C)CC2)n(C2CC2)c1=O +CC(C)(C)Oc1cc(CNC(=O)C2CCCN(C(N)=O)C2)ccn1 +Cc1cccc(CN2C(=O)CC3C2CCN3C(=O)c2ccoc2)n1 +COc1ccc(C(C)Nc2ccc(=O)n(C)c2)cc1 +CC(=O)N1CCC2CN(Cc3cccnc3)S(=O)(=O)C2CC1 +CS(=O)(=O)N1CCC(NC(=O)c2nonc2N)CC1 +CCCC1CN(C(=O)CSc2nc3ccccc3[nH]2)CCO1 +COCCN1CCN(C(=O)C2CCCc3sccc32)CC1=O +COC(=O)N1CCCN(C(=O)NC2CCc3ccccc3C2)CC1 +CCC(C)Nc1nc(SCC(N)=O)nc(N(C)C)n1 +Cc1ccc(-c2cc(C(=O)NCC3CC3C)on2)cc1 +O=C(CC1NC(=O)c2ccccc2N=C1O)NCc1cccnc1 +COc1ncccc1CN(C)C(=O)Cc1ccc(F)cc1 +CC1CN(CC(=O)NCc2cc(Br)cs2)CCO1 +Cc1noc(C)c1C(=O)NCC12CC3CC(CC(C3)C1)C2 +Cc1ccn2c(=O)c(-c3nc(Cc4noc(C)n4)no3)cnc2c1 +CCc1ccc(NC(=O)NC2CC(=O)N(c3ccc(F)cc3)C2)cc1 +CCC(C)CSc1nnc(CCC(N)=O)n1C +N#CCc1ccc(OCc2cccc(NC(=O)Cn3cnnn3)c2)cc1 +CCCOC(=O)c1ccc(NC(=O)c2cc(C)no2)cc1 +CCN(CC)C(=O)COc1cccc(NC(=O)c2ccc(F)nc2)c1 +COc1cccc(C(=O)NCc2ccccc2OC(F)(F)F)c1 +C=CCN(C(=O)Cn1c(C(=O)OC)cc2occc21)c1ccccc1 +Cc1ccc(-c2n[nH]c(SC(C)c3nnc(CC(C)C)o3)n2)cc1 +CC(C)NC(=O)Nc1ccc(NC(=O)c2ccccn2)cc1 +CCOC(=O)c1sc(S(C)(=O)=O)nc1C(F)(F)F +COc1cccnc1NC(=O)CCNC(=O)C(C)(C)C +CC(C)NC(=O)C(NC(=O)c1ccnc2c1OCO2)C(C)C +CCOc1ccc(CNC(=O)C2CC(=O)N(c3ccccc3)C2)cc1 +Fc1ccc(NCc2nnc(C3CC3)o2)c(OCC(F)(F)F)c1 +O=C(Cn1nc(-c2ccccc2F)ccc1=O)NCc1ccccc1 +O=C(Nc1nc(CN2CCOCC2)cs1)c1c(F)cccc1F +O=C(C1CCC1)N1CCN(Cc2ccc(F)cc2)CC1 +Cc1ccc(C(CNC(=O)c2ccoc2)N2CCOCC2)o1 +OCc1nnn(Cc2ccccc2F)c1Cc1cccs1 +CCCn1nc(C(=O)NCCN2CCN(C(C)=O)CC2)ccc1=O +CCCN(C(C)C)S(=O)(=O)c1c(C)cccc1N +CC(Oc1ccccc1F)C(=O)Nc1noc(-c2ccc(F)cc2)n1 +COC(=O)c1[nH]c(C)cc1NC(=O)CCC(C)(C)C +O=C(COc1ccccc1Cl)N1CCC(Oc2ccccc2)CC1 +CN1CCOC(C(=O)NC(c2cccc(F)c2F)C(F)(F)F)C1 +Cc1ccccc1CSc1nnc(Cc2c(C)[nH]c(=O)[nH]c2=O)o1 +Cn1c(=O)c(C(O)Cc2ccccc2)cc2ccccc21 +CC(C)CNC(=O)NCCOc1cccc(Cl)c1 +Nc1ccc2c(c1)N(C(=O)CCCc1cccs1)CCS2 +Cc1ccc(NC(=O)c2ccc(S(=O)(=O)N(C)C)o2)nc1 +Cc1ccc2cc3c(nc2c1C)OCC(=O)N(Cc1ccccc1)C3 +O=C1CCc2cc(C(=O)COc3ccc(F)cc3F)ccc2N1 +O=C(c1ccccc1)N1CCN(C(=O)c2cccc3ccccc23)CC1 +Cc1ccc(O)c2c1C(c1ccc(F)cc1N)NCC2 +CC(=O)Nc1ccc(C)c(NCc2cc(Cl)cc3c2OCOC3)c1 +O=C(CN1CCOc2ccc(F)cc21)NCc1ccccn1 +COc1ccnc(S(=O)(=O)c2ccc(Cl)cc2)c1C(N)=O +CCOc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cc1F +CCCCn1c2c(cc(C(C)=O)c1=O)CN(CC)CC2 +CCN(CCO)C(=O)c1c(C)nc(C2CC2)[nH]c1=O +CC(C)N(C)C(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1 +COCCNC(=O)N1CCN(CC(=O)N2CCCCC2C)CC1 +O=C(Cn1cnnn1)Nc1ccc(C(=O)Nc2ccccc2)cc1 +CN(Cc1nc(C2CC2)no1)c1nccc(C2CCCC2)n1 +Cc1ccsc1C(=O)N1Cc2ccnn2CC(COCC2CC2)C1 +CCc1noc(CN2CCN(c3cccc(C(F)(F)F)c3)CC2)n1 +CNc1snc(C)c1C(=O)N(C)Cc1ccc(OC)c(OC)c1 +Cc1nc2ncc3c(=O)n(-c4ccc(F)cc4)ccc3n2n1 +Cc1ccn(-c2ccnc(NCc3ccccc3C)n2)n1 +CCCn1c(O)nnc1SCC(=O)NC(C)C(C)C +CC(=O)Nc1cccc(-c2nc3ccccc3[nH]2)c1 +CCCn1cnnc1C1CCCN(C(=O)CCn2nc(C)cc2C)C1 +CCN(CC)C(=O)C1CCCN1C(=O)NCc1ccncc1 +CCN(Cc1c(F)cccc1F)C(=O)c1cc(=O)c2ccccc2[nH]1 +CC(C)N(C(=O)c1cc(Cl)c2c(c1)OCCO2)C1CCC1 +CC(C)(C)NC(=O)CNC(=O)c1cc(F)cc(F)c1 +COCCC(=O)N1CC2CN(Cc3cccc(C)n3)C(=O)C2C1 +CCC(CC)C(=O)Nc1ccc(S(N)(=O)=O)c(C)c1 +COCc1nnc2sc(-c3cccc(Cl)c3)nn12 +Cn1cc(S(=O)(=O)Nc2ncn(Cc3cccc(F)c3)n2)cn1 +Cc1nc(C)c(CCC(=O)N2CCCc3cc(F)ccc32)c(=O)[nH]1 +COc1nn(C)cc1C(=O)NCc1cc(-c2ccccc2F)on1 +O=S(=O)(CCCOc1ccc2c(c1)OCO2)N1CCCC1 +CCOc1ncccc1C(=O)NC(C)Cn1ccnc1 +COCCNC(=O)NCC(O)c1cccc(F)c1 +COc1cc(OC)cc(C(=O)Nc2ccc(C(C)=O)cc2)c1 +COc1ccc(OC)c(-c2cc(C(=O)NC(C)C)ccn2)c1 +CC(NC(=O)N1CCN(c2ncccn2)CC1)c1ccncc1 +Cc1noc(CNc2ccc(C(=O)N3CCOCC3)c(Cl)c2)n1 +COc1ccc(CC(=O)NCC(O)c2ccc(C)o2)cc1OC +COc1ccc(N)c2c(C(=O)Nc3ccccc3)nccc12 +Cn1nc(-c2ccccc2)cc(C(N)c2ccc(F)cc2)c1=O +Cc1cnn(CCC(=O)NC2CCc3ccccc32)c1 +CCc1nnc(CNc2ccc(C(=O)NCC(C)C)cc2C)o1 +CCOC(=O)C1CCN(C(=O)c2c(C)cc(C)n2CC)CC1 +CN(Cc1cccc(F)c1)S(=O)(=O)c1ccc(Cl)cc1 +CCc1noc(CC)c1CC(=O)N1CC(C)OCC1C +NC(=O)C1CC(=O)Nc2nc(Nc3cccc(Cl)c3)[nH]c(=O)c21 +COCCn1cc(NC(=O)c2n[nH]c(N)n2)cn1 +COC(=O)C(C)Sc1nnc(Cc2ccc(OC)cc2)o1 +CCN1CCN(C(=O)COc2ccc(Cl)cc2C)CC1 +Cc1c(C(=O)N2CCOCC2c2ncon2)oc2c(C)cccc12 +CSc1ncccc1C(=O)NCc1ccccn1 +Cc1ccc(NC(=O)c2ccccc2)c2[nH]ncc12 +O=C(Cc1csc(NC(=O)C2CC2)n1)NC1CCCC1 +O=C(c1ccco1)N1CCN(C(=O)N2CCOCC2)CC1 +CCOC(=O)C1CCN(C(=O)CSc2nccn2C)CC1 +CCCSc1ccc(Nc2ncnc(N)n2)cc1 +CCC(=O)Nc1cnn(COc2cccc(Cl)c2)c1 +COCCNC(=O)c1cc(-c2ccc(OC)cc2)cs1 +COc1ccc(NS(=O)(=O)c2ccc(N)cc2)c(OC)c1 +CC(C(=O)Nc1ccc(OCc2ccncc2)cc1)C1CCOCC1 +N#Cc1ccccc1NC(=O)c1ccc(-n2ccnn2)cc1 +CCc1ccc(NC(=O)COC2CCCCC2)cc1S(N)(=O)=O +Cc1ccn2ncc(C(=O)Nc3ccccc3C)c2c1 +COc1cnc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1O +Cc1noc(C)c1COC(=O)C1CCCN1C(=O)c1ccccc1O +COc1ccc(OCCS(=O)(=O)N=c2cccc(C)[nH]2)cc1 +O=C(CCNC(=O)c1ccco1)NCc1cccs1 +CN1CN(c2ncnc3cc(Cl)ccc23)CC1=O +CCCCN(C)C(=O)c1noc2c1CCCCC2 +CCOC(=O)CCN(C)S(=O)(=O)c1cn(C)c(C)n1 +CNC(C)C(=O)c1cc(Br)ccc1C +Cn1cc(C(=O)N(Cc2c(F)cccc2F)C2CCCC2)ccc1=O +Nc1ccc(S(=O)(=O)NCCCc2cccc(F)c2)cc1 +CCS(=O)(=O)NC1CCc2c(Cl)cccc21 +COc1ccccc1NC(=O)Nc1ccc(C(F)(F)F)nc1C +Cc1cc(C(=O)N2CCN(Cc3nnc(C4CC4)o3)CC2)on1 +N#Cc1ccccc1NC(=O)c1cccc(NC(=O)c2ccco2)c1 +COc1cccc(CNC(=O)Nc2cc(C)nn2C)c1 +CCS(=O)(=O)Nc1cc2c(cc1N)OCCO2 +CC(=O)N(C)CC(=O)NCc1ccc(-n2nc(C)cc2C)nc1 +COc1ccc(C)cc1CCNC(=O)c1cccc(NC(C)=O)c1 +Cc1noc2ncc(C(=O)Nc3ccc(Oc4cccnc4)nc3)cc12 +CC(=O)c1cc(C(=O)OCC(=O)Nc2ccc(C(N)=O)cc2)n(C)c1 +C=CCN1CCN(C(=O)COc2cccc(C)c2)CC1 +CC(C)Cn1cc(C(=O)NCC2(N3CCOCC3)CCCC2)cn1 +CN(C)C(=O)CC1(CC(=O)Nc2ccc(O)cc2)CCCC1 +O=C1CC(COCc2ccccc2)c2c[nH]nc2N1 +COCC(C)C(=O)N1CCC(C(=O)OC)c2ccccc21 +Cc1n[nH]c(=O)nc1Nc1ccc(C(=O)OCC(C)C)cc1 +CCn1cnnc1CNC(=O)N(C)Cc1ccsc1 +O=C(CSc1ccc(F)cc1)NCC(O)Cn1ccccc1=O +O=C(CSc1nncn1-c1ccccc1F)N1CCOCC1 +CC(C)Cc1ncc(C(=O)NCCc2ccccc2)c(N)n1 +CCOc1ncccc1CNC(=O)c1cc2cccc(OC)c2o1 +Cc1cc(NC(=O)c2nc3ncc(Br)cn3n2)ccn1 +Cc1noc(NC(=O)c2sc(-c3cccs3)nc2C)n1 +CC(=O)c1cccc(NC(=O)CSc2ccncc2)c1 +Cn1ncc2c(=O)[nH]c(NCCCOCc3ccco3)nc21 +CC(C)(C)c1csc(C2CN(CCn3cccn3)CCO2)n1 +O=C(CCCc1cccs1)Nc1cccc(Cl)c1-n1cncn1 +CN(CCOc1ccccc1)C(=O)Nc1cccnc1-n1cncn1 +Cn1nnc(C#N)c1-c1ccc(Cl)c(Cl)c1 +Cc1ccc(Cl)c(C(=O)CN2CC(C)OC(C)C2)c1 +Cn1ncc2c(NCCCn3cnnc3)nc(-c3cccnc3)nc21 +CC(NC(=O)c1cc(=O)c2ccccc2o1)c1ccncc1 +C=CCNC(=O)N1CCN(c2ccc(F)cc2)CC1 +COc1cc(CCNC(=O)CCc2c(C)nc(C)[nH]c2=O)ccc1C +Cc1cc(CN2CCN(C(=O)NC(C)c3ccncc3)CC2)on1 +O=C(NCc1ccccc1F)c1cnc(C2CCCO2)s1 +C=CCN(CC=C)C(=O)c1cccc(C(=O)N(C)c2ccccc2)c1 +Cc1cnc(C(=O)NC2CCCc3cc(OC(F)F)ccc32)cn1 +CC1C(=O)N(c2ccc(F)cc2F)CCN1C(=O)Cc1ccccc1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)NC1CCCC1)O2 +CC(C)C(NC(=O)COc1ccccc1)C(=O)Nc1ccncc1 +O=C1OCCN1CCNc1nnc(C2CCC2)o1 +O=C(NC(Nc1ccccn1)C(Cl)(Cl)Cl)c1ccco1 +O=C(Nc1ccc(F)c(NC(=O)C2CC2)c1)c1cc(F)cc(F)c1 +Nc1cccc2c1nc(Cc1ccc(Cl)cc1)n2CCO +N#CCC(COc1ccc(F)cc1F)N1CCOCC1 +CCN(C(=O)c1cc(C)sc1C)c1ccccc1 +O=c1ccn(CCc2nc(C3CCCCC3)no2)c(=O)[nH]1 +N#Cc1sc2nc(N)c(C#N)c(-c3ccc(O)cc3)c2c1N +N#CCCC(C#N)Cn1ncnc1-c1cccc(C#N)c1 +COCCNC(=O)c1cc2c([nH]c1=O)CC(c1ccccc1)CC2=O +Cc1ccc(-c2n[nH]cc2CN2CCOC(c3cccc(O)c3)C2)o1 +C=CCN1CC(c2nc3ccccc3n2CC=C)CC1=O +Cc1ccc(Br)cc1C1NCCNC1=O +Cc1ccc2[nH]c(=O)c(COC(=O)c3ccccc3C)cc2c1 +Cc1cccc(NC(C)C(=O)Nc2nccs2)c1 +O=C(c1nc(-c2ccccc2)n(-c2ccccc2)n1)N1CCOCC1 +CN(C)C(=O)c1cccc(NC(=O)CC2CCCC2)c1 +Cc1ccc(CC(=O)NC(C)(C)c2cccc(Cl)c2)cn1 +COC(=O)C(C)NC(=O)c1c(C)[nH]c2ccccc12 +CCSc1nnc(SCC(O)c2ccccc2)s1 +CCC(NC(=O)c1cccc(C#N)c1)c1nccs1 +Cc1ncc(CNC(=O)C2CC2c2ccc(C(C)C)cc2)s1 +Cn1c(C(=O)OCC(N)=O)cc2cc(C(F)(F)F)ccc21 +COc1ccc(CCc2nc3ccc(N)cc3o2)cc1OC +CCC(=O)NCC(=O)NCc1ccc(C(=O)N(C)C)cc1 +O=C(Nc1ccccc1N1CCCC1=O)c1cc[nH]n1 +CCOC(=O)NCCC(=O)NC1CCCNC1=O +CC(OC(=O)Cc1ccc(C(F)(F)F)cc1)C(N)=O +CC(C)C(NC(=O)c1ccco1)C(=O)Nc1ccccc1Cl +O=C(CCC(=O)Nc1nccs1)NCc1ccoc1 +Cc1cnc(C(=O)Nc2ccc(S(=O)(=O)N3CCCC3)cc2)cn1 +Cc1ccc(-c2nnco2)cc1NC(=O)NC(C(N)=O)C(C)(C)C +COc1ccc(NC(C)C(=O)N2CCN(c3ncccn3)CC2)cn1 +CN(CCO)c1nc2cc(-c3nccs3)ccc2[nH]1 +CC(C)c1ccc(CN(C)C(=O)c2cnn(C)c2-n2cccc2)cc1 +Nc1cc2c(cc1Sc1ccccc1Cl)NC(=O)C2 +CCOC(=O)N1c2cc(OC)c(OC)cc2C(=O)CC1C +Cc1cc(=O)n2c(n1)SCC2CC(=O)Nc1ccc2c(c1)OCO2 +CCc1nc2n(n1)CC(NCc1cnc(N3CCOCC3)nc1)CC2 +CCCCn1ncc(-c2cc(C)ccc2OC)c(C#N)c1=O +CC(=O)c1cccc(NC(=O)c2cc3sccc3n2C)c1 +O=C(CNC(=O)c1cnccn1)Nc1nc(-c2ccncc2)cs1 +Cc1nc(-c2scnc2C)n(Cc2c(F)cccc2Cl)n1 +Clc1cccc2c1C(CCOc1ccccc1)NCC2 +Cc1ccccc1N1CC(C(=O)N2c3ccccc3CC2C)CC1=O +CC(C)COc1ncccc1C(=O)N1CCC(c2nncn2C)CC1 +CC(NC(=O)NCCC1CCCCC1)C1CCCO1 +Cc1cc(C(=O)Nc2cc(C)nn2C)c2ccccc2n1 +COCCOc1ccccc1NC(=O)c1cc2ccccc2c(=O)[nH]1 +O=C(NCCn1ncccc1=O)c1cccc(F)c1 +O=C1OC2CC1N(C(=O)c1nc3ccccc3s1)C2 +CCc1ccsc1C(=O)NCCCn1cccn1 +CS(=O)(=O)N1CCC(C(=O)OCc2ccccc2F)CC1 +COc1cc(OC)c(-c2cnc(N)o2)c(OC)c1 +COc1cccc(C(O)Cn2cnc3sc(C)cc3c2=O)c1 +CC(=O)N1CCc2cc(NCc3ccccc3Br)ccc21 +Clc1ccccc1OCc1noc(C2CC2)n1 +Cc1ccc(-n2nnc(C(=O)Nc3cccc(C(C)O)c3)c2C)cc1 +O=C(CCNC(=O)c1cc2ccoc2s1)NC1CCCCC1 +COc1ccc(NC(=O)CCC(=O)c2cccs2)cc1OC +O=C(Cc1cccc(F)c1)N1CCCN(C(=O)Cc2ccc[nH]2)CC1 +NC(=O)c1n[nH]c2ccc(NC(=O)CCc3ccsc3)cc12 +O=C(Nc1ccc(S(=O)(=O)C(F)F)cc1)C1CCC1 +N#Cc1cccc(OCC(=O)NC2CCCc3ccccc32)c1 +Cc1cccc(C(C)C)c1NC(=O)Cn1cnc2c(C)cccc2c1=O +CC(CNC(=O)c1ccccc1OCC(N)=O)N1CCOCC1 +CCCc1ccc(C(O)CNC(=O)Cc2ccccc2)cc1 +CCOc1c(N)cc(-c2nc(C)cs2)cc1OC +N#Cc1ccc(N)c(NS(=O)(=O)c2ccc3ccccc3c2)c1 +CC(Nc1ccc2nnnn2n1)c1ccc(NC(=O)C2CC2)cc1 +CCn1cc(NC(=O)C(C)NC(N)=O)ccc1=O +O=C(c1cccc(Cn2cccn2)c1)N(Cc1nccs1)C1CC1 +COCCn1cnnc1SC(C)C(=O)NC1(C#N)CCCCC1 +O=C(Nc1ccc(-n2ccnc2)nc1)c1cccc2ccccc12 +CN(C)c1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)cn1 +Cc1cc(C)n2nc(C(=O)NCc3ccco3)nc2n1 +Cc1cccc(OC(C)C(=O)N(C)Cc2cccc(C#N)c2)c1 +Cc1cc(NCc2nnc(C)n2C)c(C(N)=O)cc1F +Cc1ncn2cc(-c3ccc(Cl)cc3)[nH]c(=O)c12 +O=C(NCC1(C2CC2)CC1)c1cnc(C2CCCO2)s1 +O=C(c1ccccc1)N1CC2CCCC2(COCC2CCOCC2)C1 +Cc1ccc(CC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1C +CC(C)(c1ccccc1)c1nnc(NC(=O)c2ccncc2F)s1 +COc1cccc2ccn(CC(=O)NC3CCCCC3)c12 +O=c1[nH]c2ccc(S(=O)(=O)NCCc3ccccc3)cc2[nH]c1=O +COCC(C)NC(=O)CSc1nccn1-c1cc(C)cc(C)c1 +C#CCN(Cc1ccco1)S(=O)(=O)c1cnc2c(c1)c(C)nn2C +C=C(C)CN(CC)C(=O)C1CCCN1C(=O)Cc1ccccc1 +CCC1CCCCN1C(=O)Cn1cc(Cl)c(=O)[nH]c1=O +CCC(C)C(=O)NC1CCOc2ccc(C(C)O)cc21 +COc1cccc(NC(=O)NCCn2ccc(-c3ccccn3)n2)c1 +COc1cccc(Oc2nccnc2C2CCN(C(C)=O)CC2)c1 +CN(Cc1ccnn1C)C(=O)NC1CCCCC1 +Cc1ccc(N2CCC3C(=O)NCC(c4nc(C)no4)C3CC2)nn1 +CC(C)(C)c1nnc(SCC(=O)N2CCCCC2)n1N +O=C(CO)NCCc1cccc(Br)c1 +O=C(Cc1csc(-c2ncccn2)n1)NCc1ccncc1 +CCCCn1c(N)c(N(CC)C(=O)c2ccncc2F)c(=O)[nH]c1=O +Cc1ccc(NC(=O)N(CC(C)C)CC(C)C)cc1-n1cnnn1 +CCCCC(=O)NC1CCN(CC(F)(F)F)C1 +NC(=O)c1cccc(NCC(=O)Nc2ccccc2)c1 +CCC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +O=S(=O)(NC1CCCC(O)C1)c1ccc2c(c1)CCCC2 +CN(CCc1ccc(F)cc1)C(=O)c1n[nH]c2ccccc12 +CN(C(=O)c1ccccn1)C(c1cccc(F)c1)c1ccccn1 +CCN(CC)c1ccc(C(=O)NC(C)C(=O)OC)cc1 +CN(CCOCC1CC1)S(=O)(=O)c1c[nH]c2nccc(Cl)c12 +Cc1cccc(CNC(=O)NCc2sccc2C)n1 +Cc1nc(-c2cccc(F)c2)ncc1Br +O=C(CCc1nc2ccccc2[nH]1)N1CCC(N2CCNC2=O)CC1 +CCOc1ccccc1OCC(=O)NCc1ccccc1F +COC(=O)c1cnc(NC(=O)C(C)Oc2ccc(F)c(F)c2)s1 +CCS(=O)(=O)N(CCO)c1cccc(OC)c1 +CCOc1ccc(NC(=O)CC2CC(C)(C)OC2=O)cc1 +COc1ccccc1-c1noc(CCC(=O)N2CCOCC(O)C2)n1 +Cc1ccc(C(=O)Nc2ccccc2C(F)(F)F)cn1 +CCC(CC)C(=O)Nc1cc(C(=O)N2CCOCC2)cn(C)c1=O +Cc1nn(C(C)C)c2cnn(CCNC(=O)c3ccco3)c12 +CCC(C)n1ncc(C(=O)N(C)c2nccs2)c1C1CC1 +CSc1nc2sc3c(c2c2nnnn12)CC(C)(C)OC3 +Cc1nnc(COc2ccc(NC(=O)c3ccoc3)cc2)o1 +O=C(c1cscn1)N1CCN(CC2CCCO2)CC1 +O=C(c1cnc(-c2ccccc2)nc1)N1CCc2cc(F)ccc2C1 +Cc1nc(-n2nnc(C#N)c2CC(C)C)sc1C +CN(CC(F)(F)F)C(=O)CSc1nc(-c2ccccc2F)n[nH]1 +Cc1ccccc1OC(C)C(=O)Nc1cccc(C#N)c1 +CCc1c(-c2csc(NCC3CCCO3)n2)[nH]c(C)c1C(C)=O +CCOc1cc(CNC(=O)NCc2ccccc2F)ccn1 +O=C(CCC(=O)Nc1ccccc1F)Nc1ccccc1F +NC(=O)c1ccc(NCc2nnc(-c3ccc(F)cc3)o2)cc1 +CCNC(=O)c1cnc(Cc2ccc(F)cc2)s1 +Cc1ccccc1NCC(=O)N(C)Cc1ccccc1 +COc1cc(NCCCN2CCOCC2)nc(C(C)C)n1 +CCOC(=O)CN(C(=O)c1ccc(Cl)cc1F)C(C)C +COC(=O)c1ccc(Cc2ccc(C(=O)OC)o2)o1 +Cc1cc(NC(=O)CCS(=O)(=O)c2ccc(Cl)cc2)n(C)n1 +Cc1ccc(NC(=O)c2cc(-c3ccccn3)[nH]n2)cc1N(C)C +COc1ccnc(NC(=O)c2ccc(-c3ccc(F)cc3)o2)c1 +CCOCC1CCN(C(=O)Nc2cc(F)cc(Br)c2)C1 +CCOC(=O)Nc1cccc(NC(=O)NC(C)c2nc(C)no2)c1C +CN(Cc1ccccn1)Cc1ccccc1OC(F)(F)F +CCCCC(=O)NCc1ccc(N2CCCCC2=O)cc1 +O=C(NCCO)c1cccc(S(=O)(=O)N2CCCCC2)c1 +COc1ccccc1S(=O)(=O)N(C)C1CCC(C)CC1 +COC1(C)CC(NC(=O)N2CCCC(CO)C2)C1(C)C +Cc1cc(C(=O)N2CCN(CC(C)O)CC2)no1 +CCN(CC(C)C#N)C(=O)CSc1ccc(OC)cc1 +Cn1ccc(C(=O)Nc2ccn(Cc3cccc4ccccc34)n2)n1 +O=C(OCc1cc(-c2cc3ccccc3o2)on1)c1ccc(=O)[nH]c1 +COc1ccc(C#CCNC(=O)c2ccccc2F)cc1 +CCc1cnc(NC(=O)c2cnn(-c3ccncc3)c2C)s1 +O=C(C1Cc2ccccc2O1)N1CCCC1Cn1cccn1 +O=c1c(CN(CCO)Cc2cccs2)coc2ccc(Cl)cc12 +COC(=O)Cc1nccc2cc(OC)c(OC)cc12 +NC(=O)Cn1nc(C2CC2)c2cnn(-c3cccc(Cl)c3)c2c1=O +CCOc1ccc(NC(=O)CNc2cccc(C(N)=O)c2)cc1 +Cn1nc2n(c1=O)CCN(C(=O)c1cccc3ncccc13)C2 +CCCn1nnnc1CN1CCc2ccc(Cl)cc2C1 +O=C(NCC(CO)Cc1ccc(Cl)cc1)c1ccncc1Cl +CC(C)(C)n1ncc2c(=O)[nH]c(NCC3Cc4ccccc43)nc21 +O=C(CSc1ccc2ccccc2n1)N1CCOCC1 +COc1ccc(-c2cnc(Cn3cccc(C)c3=O)o2)cc1 +CS(=O)(=O)c1ccc(NCCCN2CCOCC2)c(F)c1 +O=C(NCCn1c(C(F)(F)F)cc(=O)c2cccc(F)c21)C1CC1 +CCOc1ccc(C2NC(=O)NC(C)=C2C(=O)N(C)C)cc1 +NC(=O)Cc1cccc(OS(=O)(=O)c2ccc(Cl)cc2)c1 +CCCOCC1CCN(C(=O)Cn2cccc(OC)c2=O)C1 +CCn1nc(-c2cccs2)cc1C(=O)NC(C)C +COc1ccc2nc(C)cc(C(=O)NCc3cc(C)on3)c2c1 +Cc1ccc(-n2c(SCC#N)nnc2N2CCCC2)cc1 +O=C(NCCc1cn2ccccc2n1)c1cccc(C(F)(F)F)c1 +Cc1nn(-c2ccccc2)nc1C(=O)OCC(=O)N1CCCCC1C +O=C(Cn1c(=O)oc2ccccc21)Oc1c(Cl)cccc1Cl +Cc1ccc(-c2nnc(C(C)N(C)CCc3nccs3)o2)cc1 +COc1c(C)cc(-c2cnn(C)c(=O)c2N)cc1C +O=C(NC1CCc2c(O)cccc21)c1cnc2ccccn2c1=O +O=S(=O)(CC1CCCCC1)Nc1cnn(-c2ccccn2)c1 +O=C(c1cc[nH]n1)N1CCOC2C(CNc3cccnc3)CCC21 +Oc1cccc2c1Oc1nc3ccccc3nc1O2 +CC(=O)NCCOC(=O)c1c(NC(=O)C(C)(C)C)sc(C)c1C +Cc1ccc(Cc2nc(-c3ccc4c(c3)[nH]c(=O)c(=O)n4C)no2)cc1 +COc1ccc(C23OC4C(O)C5CC4C2C5C(=O)N3C(C)C)cc1 +Cc1ccc(C(=O)NC(C)C2CCCCC2)c(=O)[nH]1 +COc1ccc(C(NC(=O)C2CCCOC2)C2CCOCC2)cc1 +CNc1ncnc(Nc2ccccc2C(F)(F)F)c1N +CCCCN(C)C(=O)c1nccnc1NC(=O)c1ccccc1 +CCOC(=O)N1CCN(C(=O)c2cn(C)nc2C)CC1 +COc1nc(N2CC(C(N)=O)CCC2C)ccc1N +Cc1ccc(C(=O)NCC(=O)NCC2CCC2)cc1C +CCOc1ccc(CN(C)C(=O)c2ccc3c(c2)OCCO3)cc1 +NC(c1cc(C(F)(F)F)cc(Cl)c1Cl)C(F)(F)F +CN(CC1CC1)C(=O)C(Cc1c[nH]c2ccccc12)NC(N)=O +Cc1noc(C)c1S(=O)(=O)Oc1cccc(F)c1 +O=C(CCCC(O)c1ccc(F)c(F)c1)NCc1ccco1 +Cc1ccncc1NC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +C=C(C)C(O)COc1c2ccoc2c(OC)c2oc(=O)ccc12 +CN(C(=O)c1cccc(OCC(N)=O)c1)c1ccc2ccccc2c1 +CC(C(=O)N1CCCC1)N1Cc2ccccc2C1=O +COc1ccc(C(=O)N2CCCCC2CCc2ccccc2)nn1 +CN(CC1CC1)C(=O)COc1ccc(CC(N)=O)cc1 +COc1ccc(-c2ccnc3nc(C(C)C)nn23)c(F)c1 +COc1ccc(CCCNC(=O)N2CCC(CC(N)=O)CC2)cc1 +N#Cc1ccc(C(=O)N(Cc2cnc3ccccn23)C2CC2)cc1 +N#Cc1cccc(C(=O)OCC(=O)NCCc2ccccc2)c1 +Fc1cc2c(c(F)c1F)CCNC2c1ccco1 +CCc1nnc(NC(=O)CCCOc2ccc(C)cc2)s1 +C=CCNC(=O)COc1ccc2c(c1C)OC(C)(C)CC2=O +CC(C)(C)OC(=O)N1CCC(C(=O)NCc2ccc(Cl)cc2)C1 +CCn1nnc2cc(C(=O)OCc3c(OC)cccc3OC)ccc21 +COC(=O)Cn1c(SC(C)C)nc2ccccc2c1=O +Cc1ccc(S(=O)(=O)N2CCc3cnc(N(C)C)nc3C2)cc1 +CCn1c(=O)c2c(ncn2CC(C)C)n(-c2ccc(F)cc2)c1=O +CC(C)n1cc(S(=O)(=O)NCC2CCCC2)cn1 +CN(CC(F)(F)F)C(=O)c1cnn(C(C)(C)C)c1 +Cc1nn(C)c(C)c1NC(=O)C(C)Sc1ccc(F)cc1F +O=C(Cn1nnc2ccccc2c1=O)N1CCCC1C1CCCC1 +Cc1nc(-c2ccsc2)ccc1C(=O)N(C)c1nccs1 +COC(=O)CCCN(C)C(=O)c1cc(Cl)ccn1 +COC(=O)c1ncn(Cc2nc(CCC(C)C)no2)n1 +O=C(Nc1ccc(Cl)cc1-n1cccc1)c1ccc2nncn2c1 +Cc1cccc(CN(C(=O)CCc2cccnc2)C2CC2)c1 +Cc1oc2ncn(CC(C)C)c(=O)c2c1C(=O)NCC1CCCO1 +Cc1ccc(-c2c(C)sc3nc(CO)cn23)cc1 +N#Cc1c(F)cccc1N1CCN(C(=O)c2ccco2)CC1 +N#Cc1ccccc1NCc1nc2ccccc2s1 +CCc1ccccc1OCC(=O)Nc1cc(C)nn1CCC#N +O=C1NCCOC2CN(C(=O)c3cnc4ccccc4c3)CCC12 +CCc1nc(C)cn1S(=O)(=O)c1ccc(Cl)cc1OC +CC1=C(C(=O)NCCc2cccc(C(N)=O)c2)Cc2ccccc2O1 +Cn1cc(C(=O)Cn2nnc3c(cnn3-c3ccccc3)c2=O)cn1 +CCOc1ccc(C(=O)N(CC)Cc2ccccc2)cc1 +Cc1ccc(C)c(OCC(=O)NC2CCCNC2=O)c1 +CCNC(=O)COc1ncnc2sc3c(c12)CCCC3 +Cc1cc(F)ccc1S(=O)(=O)Nc1ccc(-n2cnnn2)cc1 +CC(C)n1ncc2cc(C(=O)NCc3ccccn3)c(N)nc21 +Cn1cnnc1SCCc1nc2ccccc2c(=O)[nH]1 +COc1ccc(C(=O)Nc2cc(C)c(C)s2)cc1 +NC(=O)c1ccc(C(=O)OCC(=O)c2cc3ccccc3o2)cc1 +CCn1nc(C(=O)Nc2nc(-c3ccccc3)cs2)cc1C +N#Cc1cccc(OCC(=O)c2ccccc2F)c1 +NC(=O)CNC(=O)c1c[nH]nc1-c1ccc(F)cc1 +CC1(C)Cc2cccc(OCC(=O)OCC(=O)c3ccc[nH]3)c2O1 +CN(CC(=O)Nc1ccccc1Cl)S(C)(=O)=O +Cc1cccc(NC(=O)NC2CCCc3ccccc32)c1 +CCCNC(=O)c1cc(Br)c(OCC)c(OC)c1 +O=C(COC(=O)c1cc(-c2ccco2)nc2ccccc12)C1=NC=CC1 +CC(C)(C)C1CCN(S(=O)(=O)N2CCN3C(=O)NCC3C2)CC1 +CNS(=O)(=O)c1ccc(N(C)C(C)C(C)C)c(N)c1 +NC(=O)COc1ccc(NC(=O)c2ccc(Cl)cc2O)cc1 +CC(=O)c1cccc(NC(=O)CSc2nnc(C)n2C)c1 +CCOC(=O)C(C)NC(=O)c1ccc(Cl)cc1N +Cc1nc(C2COCCN2C(=O)c2cc(-c3ccccc3)[nH]n2)no1 +Cc1ccc(C(=O)N2CCCC(C(F)(F)F)C2)s1 +COCCCNC(=O)C(N)c1ccc(O)cc1F +c1cnc(-c2cnc(N3CCCC3)nc2C2CCCO2)cn1 +CCn1nc(C)c(NCc2ccc(C)c(C)c2)c1C +O=C(c1cc(F)ccc1F)N1CCN(Cc2ccccc2)CC1 +CC(=O)c1ccc(S(=O)(=O)Oc2cccc3c2CCC3=O)cc1 +CCCn1cc(NC(=O)NC2c3ccccc3CC2O)cn1 +O=C(Nc1ccc(F)c(Cl)c1)c1cnoc1-c1ccco1 +COC(=O)c1oc(CN2CC(C)OC(C)C2)cc1C +CC(=O)C1C(c2ccc(Cl)cc2)c2c(noc2C)CC1(C)O +Cc1ccc(N2CC(C(=O)N3CC(c4nc(C)no4)C3)CC2=O)cc1 +Cc1cnn(CCC(=O)NCc2cccc(Br)c2)c1 +COc1ccc2oc(=O)c(-c3nc4ccccc4c(=O)[nH]3)cc2c1 +Cc1cccc(OCc2nc(C#N)c(N3CC(C)OC(C)C3)o2)c1 +Cn1cc(C(=O)NCC(=O)Nc2nccs2)cn1 +O=C(NCCc1c[nH]c2ccccc12)C1CCCN(c2cnccn2)C1 +COc1ccc(CNC(=O)CSc2nnc(C(C)(C)C)n2N)cc1 +CCNc1ncc(-c2nc(C3CC3)nn2-c2ccccc2)cn1 +O=C1CCCN1c1ccc(OCC(=O)N2CCCn3ncnc32)cc1 +CCOC(=O)c1c(C2CC2)csc1NC(=O)N1CCCCCC1 +CN(C)c1ccc(C(=O)NC2C3CCC(C3)C2CO)c(F)c1 +COc1cc(-c2ccccc2C#N)cc(OC)c1OC +Cc1ccc(C)c(C(=O)NCc2cccc(C#N)c2)c1 +CC=CCOC(=O)C1CC(=O)N(Cc2ccc(C)cc2)C1 +COC(=O)c1noc(C(=O)NC2CCCC2)c1N +Cc1n[nH]c(SCC(=O)N2CCN(c3ncccn3)CC2)n1 +COCCN1CC(C(=O)NCC2CCCc3ccccc32)CC1=O +CCOC(C)c1nccn1Cc1nc(C2CC2)no1 +O=C(Nc1ccccc1)c1nc[nH]c1C(=O)NC1CCCCC1 +CN(Cc1ccc(OC(F)(F)F)cc1)C(=O)c1ccsc1 +C=CCNC(=O)c1ccccc1NC(=O)C(CC)OC +OC(c1cc(F)c(F)c(F)c1)c1ccccc1F +CCOCC1CCCN1C(=O)c1ccccc1-c1ncc[nH]1 +CCS(=O)(=O)c1cccc(F)c1NC(=O)c1cscn1 +Cn1nc(C(=O)NCc2ccc(Cl)cc2)c(=O)c2ccccc21 +Cc1ccccc1CCC1CCCN(C(=O)c2ccc3nnnn3c2)C1 +Cc1c(-c2ccccc2)nnn1-c1ccc(F)cc1F +CSc1ccc(C(=O)Nc2ccnn2Cc2ccccc2)cc1 +CC(C)OCCCNS(=O)(=O)N1CC(C)OC(C)C1 +O=C(CCNC(=O)NC(C1CC1)C1CC1)NC1CCCC1 +Cc1cc(CCNS(=O)(=O)c2ccc3ccccc3c2)on1 +Cc1sc(NC(=O)CCOCC2CCCO2)c(C(N)=O)c1C +O=C(Nc1ccc(Cl)cc1)N1CCN(C(=O)c2ccccn2)CC1 +Cc1n[nH]c(C)c1CNC(=O)CC1OCCc2sccc21 +CC(=O)c1cncc(-c2ccc(OC(C)C)cc2)c1 +CC(Sc1nnc(C(F)(F)F)n1N)C(=O)NC1CCCC1 +N#Cc1ccc(OCCN2CCN(c3ccccc3)CC2)cc1 +COc1ccc(OC)c(-c2ccc(CO)c(=O)n2C2CC2)c1 +CC(=O)N(C)Cc1cccnc1Oc1ccccc1 +CCCCS(=O)(=O)NCC(=O)Nc1nc2ccccc2s1 +CCc1ccc(CNC(=O)NCC2CCCCO2)s1 +O=C(NCCOCCO)c1cccc(Br)c1Cl +O=C(CC1(O)C(=O)Nc2ccc(F)cc21)c1ccc2ccccc2c1 +Oc1ccc(C2C=Cc3ccc(O)cc3OC2)cc1 +Cn1ccnc1C(NC(=O)CCc1ccco1)c1ccccc1F +Cc1cc(C(=O)CN2CCN(C)C2=O)c(C)s1 +CN(CCOc1ccccc1F)C(=O)COc1ccc(F)c(F)c1 +CC(C)CNC(=O)c1ccc(NC(=O)CCC2CCCO2)cc1 +CC(=O)Nc1cccc(C(C)OC(=O)c2cccc3c2ccn3C)c1 +COc1cccc2c1OCC(NCc1ccc(C)o1)C2 +CCOC(=O)N1CCN(S(=O)(=O)c2ccc(C)s2)CC1 +CCOC(=O)CN(C)C(=O)c1cccc2[nH]ccc12 +Cc1cc2nc(C(=O)Nc3ccc(F)cc3)cc(C)n2n1 +CCCCOc1cccc(NC(=O)N2CCCC(NC(C)=O)C2)c1 +COc1ccc(F)cc1C(O)Cc1cccc(C)c1 +CC(C)n1cnnc1S(=O)(=O)Cc1c(Cl)cccc1Cl +COc1ccccc1-c1nnc(SC(C)C(=O)NC2CC2)n1N +CC(C)c1nc(-c2cc(N)ccc2Cl)nn1C +OCc1c(-c2ccco2)nc2sc(Cc3ccc(F)cc3)nn12 +CCOC(=O)N1CCC(Nc2ccc3nncn3n2)CC1 +N#Cc1ncn(CC(=O)N2CCc3cc(S(N)(=O)=O)ccc32)n1 +NS(=O)(=O)c1cccnc1NCCc1ccc(F)cc1F +CCC(C)NC(=O)Nc1ccc(OCC(N)=O)cc1 +CCOCc1cccc(NC(=O)Cc2c[nH]c3ccc(OC)cc23)c1 +Cn1nnnc1-c1cccc(NC(=O)C(C)(C)C)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1ccc[nH]1 +CCNC(=O)CN1CCN(c2ccc(C)cc2)C1=O +CCC1CN(C(=O)CSc2nnc3ccccn23)CCO1 +CC(=O)c1cccc(NC(=O)c2ccc(-n3nc(C)cc3C)cc2)c1 +COC(=O)C(c1ccc(OC)c(OC)c1)N(C)C +CC(=O)Nc1sc(C)c(C)c1C(=O)OC(C)C(=O)NC1CC1 +CN(c1cnn(C)c1)S(=O)(=O)c1ccc(Br)cc1F +CC(C)n1nccc1NC(=O)N(Cc1ccco1)Cc1cccs1 +O=C(Nc1nc2c(s1)CN(C(=O)c1ccco1)CC2)C1CCC1 +CCN(CC(=O)OC)Cc1cc(Br)cs1 +COc1ccc(S(=O)(=O)Nc2ccncc2)c(C)c1F +CCOC(=O)Nc1cccc(C(=O)Nc2cccc(C(C)=O)c2)c1 +Cc1ccccc1CC(=O)Nc1cccn2c(C)nnc12 +O=C1CC(C(=O)NCCc2ccc(Cl)cc2)c2ccc(F)cc2N1 +CCn1c(C2CCCN(C(=O)c3ccc(=O)[nH]c3)C2)nn(C)c1=O +Cc1ccccc1C(=O)NCc1nnnn1-c1ccc(F)cc1 +CCOC(=O)C1CCCCN1Cc1cnoc1-c1ccccc1 +CC(=O)c1cccc(NC(=O)CCC(=O)c2ccc(C)cc2)c1 +O=C(Cn1ccnc1)N1CCCCC1c1nc2ccccc2[nH]1 +CCN1C(=O)COc2ccc(CC(C)(C)Br)cc21 +CSc1ccc(OC(C)C(=O)N(C)Cc2cc(C)on2)cc1 +CCCC1C=CCN1C(=O)CSc1nnc(C)s1 +Cn1cccc1CN(C(=O)c1cccc(Cl)c1)C1CC1 +CN(Cc1nncn1C)S(=O)(=O)c1cccs1 +COCCN1CC(C(=O)OCc2ccccn2)CC1=O +O=C(CCCOc1ccc(Cl)cc1Cl)Nc1cc[nH]n1 +Cc1sc2nc(N3CCCCC3)n3ncnc3c2c1C +Nc1ccc(SCc2nc3ccccc3[nH]2)c(Cl)c1 +CCC(C)NS(=O)(=O)c1ccc(N2CCCC2=O)cc1C +Cc1cccc(NC(=O)CCc2cccc(F)c2)c1C(N)=O +O=C(c1cc(-c2ccccc2)on1)N1CCC2(CC1)OCCO2 +CCOc1ccc(NC(=O)c2ccno2)cc1OCC +CC(C)c1nc(C2CCCN2C(=O)CCCNc2ncccn2)no1 +CN(CCC(=O)OC(C)(C)C)C(=O)c1ccc(-n2ccnn2)cc1 +CC(C)=CCN1CC(NC(=O)c2ccoc2)CC1C(=O)NC(C)C +COc1ccc(NC(=O)c2cccc(-n3cnnn3)c2)cc1Cl +N#Cc1cc(F)cc(C2NCCc3c(O)cc(O)cc32)c1 +CCc1ccccc1NC(=O)CSc1nc(C)c(C)o1 +CC(NCC(O)c1ccc(C#N)cc1)c1cccc(N2CCCC2=O)c1 +CN(CCc1ccc(F)cc1)C(=O)c1cccs1 +CC(NC(=O)CCSc1nnnn1C(C)C)c1ccccc1 +CC1OCCN(C(=O)Nc2ccc(F)cc2OCC(F)F)C1C +Nc1ccc2oc(-c3ccc(OC(F)F)cc3)nc2c1 +CN(Cc1ccccc1)C(=O)c1ccc(Cl)c2cccnc12 +C=CCn1c(C)nnc1SC(C)C(=O)N1CCCc2ccccc21 +CCNC(=O)C(C)NC(C)c1ccc(OCC)cc1 +CCOc1ccccc1C(=O)N1CCCC(C(N)=O)C1 +CNc1ccc(Cl)cc1C(=O)N(C)CC(C)C +CCc1cc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)sc1C +NS(=O)(=O)c1ccc(N2CCN(c3cnccn3)CC2)c(F)c1 +COc1cccc(CN(C)C(=O)c2c[nH]cc2-c2ccc(F)cc2)c1 +Cc1c(C(=O)N2CCN(C(C)C)CC2)cnn1-c1cccc(Cl)c1 +CC(NC(=O)c1cc(Br)ccc1Cl)C(N)=O +Cc1csc(C2(NC(=O)NCCN3CCOCC3)CCCC2)n1 +N#Cc1ccccc1N1CCN(C(=O)c2ccc(Cl)cc2)CC1 +COCCN(C)C(=O)CS(=O)(=O)NC1CCC(C)CC1 +COc1ccc(OC(C)C(=O)NC2(C#N)CCCCC2)cc1 +CCOc1cc(C#N)ccc1OC(=O)c1cccn1C +Nc1ccc2c(c1)CCCN2C(=O)c1cc2ccccc2o1 +CN(C)c1nc(N)nc(CN2CCC(Oc3ccc(F)cc3)CC2)n1 +Cc1cc(=O)c(C(=O)N2CCCCC2C)nn1-c1ccc(Cl)cc1 +Cc1cccc(C(C)(C)CNC(=O)CCSc2nnnn2C)c1 +CC(=O)c1ccc(NCC(=O)c2ccc3c(c2)CCC3)cc1 +CC(C)CC(=O)NCc1cccc(Oc2ccccn2)c1 +Cc1ncsc1CNC(=O)c1c[nH]c2cccc(F)c12 +O=C(NCC(=O)N1CCCc2ccccc21)Nc1ccccn1 +CCN(Cc1ccc2c(c1)OCCO2)C(=O)c1cc(C)on1 +CC(C)NC(=O)c1cccc(NC(=O)c2cc3cccnn3n2)c1 +CN(CCC1CC1)C(=O)c1cccc(OCC(F)F)n1 +COc1ccc(OC)c(S(=O)(=O)NC(C)Cc2ccco2)c1 +COc1ccsc1S(=O)(=O)N1CCc2cc(F)ccc2C1 +COc1ccccc1C(=O)N(C)c1cccnc1N(C)C +C#Cc1cccc(N(CC(=O)NC)C(=O)CCCOC)c1 +CCNc1ncc(C(=O)NCc2ccc3c(c2)CCCO3)cn1 +Cc1ccc(C(=O)NC2CC(=O)N(CCc3ccc(F)cc3)C2)cn1 +CCOC(=O)c1cc(C(F)(F)F)n2ncc(C(=O)OCC)c2n1 +CC(=O)Nc1ccc2c(c1)[nH]c(=O)c1ccccc12 +CCOC(=O)C(C)NC(=O)c1ccc(N(C)C)c(F)c1 +Cc1cc(C(=O)N(C2CC2)C2CCOc3cc(C)c(C)cc32)ncn1 +Cc1nc(C)c(C(=O)Nc2nnc(CC(C)C)s2)s1 +CN(Cc1nccn1C(F)F)C(=O)CNC(=O)Cc1ccccc1 +CCCC(=O)N1CCCN(Cc2nc3cc(Cl)ccc3n2C)CC1 +CCOC(=O)C(C#N)(COC)C(C)(C#N)c1ccccc1 +COc1cc(C#N)ccc1OCC(=O)c1ccc(C)cc1 +COC(=O)c1cccc(NC(=O)c2cc(OC)c(OC)c(OC)c2)c1 +CC1CN(C(=O)Cc2coc3cc4c(cc23)CCC4)CC(C)O1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)NC(C)c3ccc(C)o3)ccc21 +NC(Cc1ccccc1)C(=O)NCCc1cccc(Cl)c1 +CCC(C)NC(=O)C(NC(=O)c1c(F)cccc1F)C(C)C +O=C(COC(=O)CC1CC2CCC1C2)Nc1ccccc1Cl +Cn1cnc(CNC(=O)c2ccc(F)cc2OC(F)F)n1 +O=C(Nc1cnn(Cc2ccc(F)cc2)c1)c1ccccc1 +COc1cccc(OC)c1-c1nccn1Cc1ccccc1C#N +Cc1cc(C)n2nc(C(=O)Nc3ccc(C)c(F)c3)nc2n1 +CCOc1ccc2cc(C(=O)NC(C)C(=O)OC)[nH]c2c1 +COc1ccc(CNC(=O)NCCC(=O)N2CCCCCC2)cc1C +C=CCCC(=O)Oc1ccc(OC2CCCCNC2=O)cc1 +CC(=O)N1CCC(C(=O)N(CCc2ccccc2)C2CCCC2)CC1 +COCc1ccc(CNc2ncnc3ccccc23)cc1 +O=C(NC1CCN(c2nccc(C(F)(F)F)n2)CC1)c1ccco1 +Cc1nnc(SCCNC(=O)c2cn3ccccc3n2)s1 +Nc1c(-c2nc(-c3cccs3)no2)nnn1-c1ccc(Cl)cc1 +Cc1csc(CNC(=O)NCC(O)c2ccc(F)c(F)c2)n1 +COC(C)C(=O)N(CC(F)F)c1cccc(Cl)c1 +C#Cc1cccc(NCC(=O)Nc2ccc(F)cc2)c1 +Nc1ccc2c(C(=O)N3CCCCCC3)nccc2c1 +Cc1nc(-c2cc(C(=O)Nc3ccc(Cl)cc3F)n(C)c2)cs1 +C#CCNC(=O)Cc1csc(-c2ccc(CC)cc2)n1 +CC(CNC(=O)N1CCOC(C)(C)C1)Oc1ccccc1 +COc1ccc(C2CCCN2C(=O)Cn2cccn2)cc1OC +CN(C)S(=O)(=O)c1ccc(Cn2ccc(-c3ccc(F)cc3)n2)o1 +COC(=O)C1CCN(c2ncc(N)cc2OC)CC1 +CC(=O)c1ccccc1OCC(=O)Nc1ccc(C)c(C)c1 +O=C(CSc1ccccn1)c1ccc2c(c1)CCO2 +CCN(C(=O)CN1CCN(C(C)C(=O)N2CCCC2)CC1)C1CC1 +CC(C)(CNC(=O)CNC(=O)Cc1cccc(F)c1)c1ccncc1 +COc1cccc(C(N)c2nc(-c3ccncc3)n[nH]2)c1 +O=C(Nc1ccc(F)c(Cl)c1)c1ccc(F)cc1-n1cnnn1 +COc1ccccc1N1CCN(CC(=O)NC2CC3CCC2C3)CC1 +O=C(CCS(=O)(=O)N1CCNCC1)Nc1ccc(F)cc1F +Cn1cnnc1SCC(=O)Nc1sc2c(c1C#N)CCCCC2 +COC(=O)Cc1csc(NC(=O)c2ccc(C)cc2O)n1 +CCN(C(=O)NCCCC(=O)OC)c1ccccc1 +O=C(NCC1CCOC1)Nc1cc(F)ccc1F +O=c1cnc2ccccc2n1Cc1cc(F)ccc1F +CC(=O)NC1CN(Cc2ccccc2C#N)CC1c1ccc(C)cc1 +CCc1nc(COC)cc(OCc2ccccc2)n1 +COc1ccc(Cl)cc1N(C(C)C(=O)N(C)C)S(C)(=O)=O +CS(=O)(=O)N1CCCC12CCCN(C(=O)c1ccc(F)cc1)C2 +NC(=O)CN1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +CCN(C(=O)Cc1ccc(NC(=O)NCCO)cc1)c1ccccc1 +Cc1ccccc1OC1CN(C(=O)c2ccc3cccc(F)c3n2)C1 +CC1CCN(C(=O)Nc2ccc3c(c2)COC3)CC1 +CCC(NC(=O)N1CCN(CC(F)F)C(CC)C1)c1nccs1 +Cc1nn(CC(C)C)c(C)c1CCC(=O)Nc1cccnc1 +Cc1cc(C(=O)CN2CCOCC2C2CC2)c(C)n1C1CC1 +N#CC1(C(=O)NCc2ccc(OCc3ccccn3)cc2)CCCC1 +O=C(COc1ccc(F)cc1)NCc1ccccn1 +CC(NC(=O)c1ccnc(OC2CCC2)c1)C1CC1 +Cc1noc(C2COCCN2C(=O)c2coc3ccccc23)n1 +O=S(=O)(Nc1cn[nH]c1)c1cccc2ccccc12 +COc1ccc(Br)cc1-c1nnc(C)n1C +O=C(OC1CCCC1)C1CCCN1S(=O)(=O)c1ccccc1 +O=C1CN(C(=O)CSc2ccc(F)c(F)c2)CCN1 +N#Cc1c(F)cccc1N1CCN(C(=O)CCn2cccn2)CC1 +CCC1CN(C(=O)COC)c2cc(Cl)ccc2O1 +CCc1nc2n(n1)CCCC2NC(=O)N1CCc2ccc(C)cc21 +Cc1ccc(N2CC(OCc3cccc(C)n3)C3OCCCC32)nn1 +O=C(CCCNc1ncccn1)NC1CCSc2c(F)cccc21 +Cc1nnc(C(C)Nc2ccc(Oc3cccc(C#N)c3)cc2)o1 +Cc1sc(NC(=O)c2csnn2)nc1-c1ccc(Cl)cc1 +CCOC(=O)c1cc(O)c2c(OC)c(OC)cc(OC)c2c1 +Fc1ccc(Br)c(CNc2cccc(-n3cnnn3)c2)c1 +CC(C)C(Sc1nnc(C(C)(C)C)o1)C(=O)NC1CCCC1 +CC(C)(C)c1ccc(NC(=O)NCCCC(N)=O)cc1 +CN1CC(C(=O)NC2(c3ccc(F)cc3F)CCCC2)CC1=O +Cc1ccc(C)c(-c2nc3cc(CO)ccn3c2N)c1 +COc1ccc(-n2cc(CNC(=O)c3c(C)oc(C)c3C)nn2)cc1 +COc1ccc(Cl)cc1C(=O)Nc1ccc(N)cc1C +CC(C)CCc1nc(CN2CCOC(C(N)=O)C2)cs1 +Cc1nnc(CN(C)C(=O)CN2CCCCCC2=O)o1 +CC(=O)Nc1cccc(-c2ccc(S(C)(=O)=O)cc2)c1 +CCOC(=O)c1nn(C(C)C)c2[nH]c(=O)cc(C)c12 +COc1c(NC(=O)c2ccc(F)cc2Br)c(C)nn1C +Cc1cccc(NC(=O)C(C)OC(=O)c2cccnc2)c1 +O=C(CCn1cncn1)NC1c2ccccc2Oc2ccccc21 +COc1ccc(-c2ccc(N)nc2)c(OC)c1OC +Cc1ccccc1OCn1ccc(C(=O)N(C)CC2CC2)n1 +CC(=O)N1CCCCC1c1cncc(NC2CCCC2)n1 +CN(c1ccccc1)c1ccccc1NC(=O)NC1CCCNC1=O +O=C1CCCN1c1ccc(Cl)c(-c2nc(-c3ccncc3)no2)c1 +COc1cccc(CC2CN(c3nc(C(N)=O)cs3)CCO2)c1 +CS(=O)(=O)Nc1ccccc1C(=O)OCc1ccccc1 +CC(C)C(=O)N1CCc2onc(COc3cccnc3)c2C1 +CC(C)NC(=O)N1CCC(c2nnc(-c3ccc(F)cc3)o2)CC1 +CCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(C)o1 +CCC(NC(=O)CSc1ccccc1)c1ccc(C)cc1 +Cc1ccc(=O)n(C(C)C(=O)N2CCN(c3ccc(F)cc3)CC2)n1 +O=C(Oc1ccccc1Br)C1CCCN1C(=O)C1CC1 +CC(=O)N1CC(C(=O)N2CCN(Cc3ccccn3)CC2)C1 +COc1ccc(NC(=O)CC(C#N)C(C)C)c(OC)c1 +CC(Oc1ccccc1)C(=O)NCc1ccccc1OC(F)F +O=C1CCCN1c1cccc(NCc2ccccc2C(F)(F)F)c1 +Cc1c(C(=O)NCC(=O)N2CCOCC2)nc2ccc(Cl)cn12 +CC(=O)NCCNC(=O)N1CCc2ccc(Cl)cc2C1 +COc1cccc(C(=O)CCC(=O)N2CCN(C)CC2)c1 +CN1CCN(C(=O)Cc2ccc(F)cc2F)c2cc(F)ccc21 +CNS(=O)(=O)c1ccc(C(C)NC(=O)NCc2ccncc2)cc1 +O=C(CCNC(=O)C1CCOC1)Nc1ccc(Br)cc1 +CC(C)(C)C(NC(=O)c1cc(C#N)c[nH]1)c1ccco1 +CCC(=O)N1CCN(C(=O)Cc2ccc(F)cc2F)CC1 +CCC(NC(=O)c1cnc2sc(C)cn2c1=O)c1nc(C)n[nH]1 +CN(Cc1csc(-c2ccccc2)n1)C(=O)C1CCCC(=O)N1 +N#Cc1ccccc1NC(=O)c1cccc(N2CCOC2=O)c1 +Cc1cccc(C(=O)NCC2(C(N)=O)CCOCC2)c1C +COc1cccc(Cc2cnc(NC(C)=O)s2)c1 +Cc1ccc(C)c(NCC(=O)Nc2cc(C)nn2C)c1 +Cc1ccc(C(=O)NCc2ccccc2Cn2cccn2)cn1 +CC(=O)N1CCC(NC(=O)C(NC(=O)c2ccccc2)C(C)C)CC1 +CCN(C(=O)Cc1nc2cc(N)ccc2o1)c1cccc(C)c1 +Cc1nc(C(=O)NCC#Cc2ccc(F)cc2)cs1 +CC1CCCC(C)N(C(=O)CCOc2cccc(C(N)=O)c2)C1 +CN1CCN(C(=O)C2CCCN2C(=O)c2cccs2)CC1 +Cc1nc2ncccc2cc1C(=O)N1CCn2c(C(N)=O)cnc2C1 +CC(=O)NC(C(=O)N(C)Cc1ccc(Br)cc1)C(C)C +O=C(CCNC(=O)c1ccco1)OC1c2ccccc2-c2ccccc21 +COCCC(=O)Nc1cnn(Cc2ccccc2F)c1 +CCC(CC)NC(=O)c1nc(N2CCCC2)c2c(C)scc2n1 +O=S(=O)(NCCC(O)c1ccccc1)c1ccccc1 +CCNC(=O)c1cc(S(=O)(=O)NC2CCCCCC2)cs1 +Cc1cc(C)cc(Nc2nc(N)c(C#N)c(CC#N)c2C#N)c1 +Cc1nc(CNC(=O)c2cc(-c3ccccc3)no2)c(C)s1 +COC(=O)CNC(=O)NCCOc1cccc(Cl)c1Cl +CC(C)c1nccc(-c2nc3ccccc3n2C)n1 +CCc1[nH]c(C(=O)Nc2c(C)cccc2C)c(C)c1C(=O)OC +Cc1ccccc1OCC(C)NC(=O)C1CCC(=O)N1 +CCCOC(=O)c1cc(-c2ccc(F)c(F)c2)n[nH]1 +N#Cc1cccc(N2CCC3(CC2)Nc2ccccc2NC3=O)n1 +CC(c1ncnn1Cc1ccccc1)n1cncn1 +Cc1ccc(C(=O)N(C)Cc2cnn(Cc3ccccc3)c2)cc1 +Clc1cccc(-n2ncc3c(NC4CC4)ncnc32)c1 +CC1CN(C(=O)NC(C)c2ccc(-c3cccnc3)cc2)CCO1 +N#Cc1cccc(CN(CC2CCCO2)CC2CCCO2)c1 +Cc1noc(C)c1CC(C)NC(=O)c1cn(C)nc1C(C)(C)C +CN(Cc1cccc(Cl)c1)C(=O)c1ccc(F)cc1F +O=C(NC1CCCCC1)c1cc2ccccc2oc1=O +COc1ccc2c(c1)CCCN2C(=O)C1Cc2ccccc2C(=O)O1 +CCCC(=O)N1CCCC(C(=O)NC(C)C(=O)OC)C1 +Cc1ccc(S(=O)(=O)N2CCCC(C(=O)OC(C)C)C2)cc1 +CCC(OC(=O)c1cccs1)C(=O)NCc1ccco1 +CCN(Cc1noc(CC(C)C)n1)C(=O)c1[nH]nc2c1CC(C)CC2 +CN(c1cccc(F)c1)S(=O)(=O)c1cn[nH]c1 +NC(=O)C1CCN(C(=O)CCc2ccc(F)cc2)C1 +Cc1cccc(NC(=O)N(C)Cc2ccc(O)cc2)c1C +O=C(NCCCn1cnc2ccccc21)c1cccc(-c2ccoc2)c1 +Nc1ccc2c(-c3ccccc3CN3CCOCC3)n[nH]c2c1 +Cn1ccc(-c2cc(C(=O)Nc3cccc(F)c3)c3ccccn23)n1 +CC(C)Oc1ncc(S(N)(=O)=O)cc1OC1CC1 +COC(=O)CC1CN(Cc2cccc(Cl)c2Cl)CCO1 +O=C(NCc1ccccc1)c1ccc2c(c1)NC(=O)C1CCC(=O)N21 +CN(CCC(F)(F)F)C(=O)NC1CCOCC1 +O=C(Nc1nccs1)C1CCCN1C(=O)Oc1ccccc1 +CCN1C(=O)c2ccc(Cl)cc2NC12CCN(C(=O)C1CC1)CC2 +O=C(Nc1cc(Cl)ccc1-n1cncn1)C1CCCO1 +CCOc1ccccc1CNC(=O)c1ccc(C(=O)OC)nc1 +CCc1nc(CC(=O)N2CCc3ccc(Cl)cc3C2)cs1 +CC(NC(=O)C1CC=CC1)c1ccc(OC(F)F)cc1 +COc1cccc(NC(=O)CNc2ccccc2N2CCCC2=O)c1 +COc1ccc(-c2noc(COC(=O)C=C(C)C)n2)cc1OC +Cc1ccccc1C(=O)N1CCC(CSc2ccccn2)CC1 +Fc1cnc(N2CCOC3(CCN(Cc4nccs4)CC3)C2)nc1 +CCOC(=O)C1=C(N)Oc2[nH]c(=O)[nH]c(=O)c2C1c1ccc(C)s1 +COc1ccc(NC(=O)c2cc(F)ccc2F)cc1OC +O=C(CSc1ncnc2c1cnn2-c1ccccc1)N1CCCC1 +CCOC(=O)C1=C(C)NC(C)=C(C(=O)OCC)C1c1ccco1 +Cc1cccc(NC(=O)c2c[nH]nc2-c2ccccc2F)n1 +CCCc1cc(=O)[nH]c(SCc2nnc(C3CCC3)o2)n1 +Cc1ccc2nc(C)cc(NC(=O)c3ccco3)c2c1 +Cc1ccc(C#CCO)cc1NC(=O)OCC(C)C +CCOc1ncccc1CNC(=O)C1CC=CCC1 +Cc1n[nH]cc1NC(=O)c1oc2ccc(F)cc2c1C +CC(C)(C)CC(=O)Nc1cnc(N2CCCC2)nc1 +Cn1cc(C(N)=O)c(NC(=O)c2ccc(Br)cc2)n1 +CCCNC(=O)CCNC(=O)NCC1(C)CCCC1 +N#Cc1ccnc(SCc2cnn(-c3ccccc3)c2)c1 +COc1ccc(C(=O)c2c(C)[nH]c3ccccc23)cc1OC +Fc1cccc(-c2noc(C3CCCN(Cc4ccccn4)C3)n2)c1 +CCc1nc(C(=O)N2CCC(Nc3ccccc3OC)CC2)c[nH]1 +COc1nn(C)cc1C(=O)NCC(=O)Nc1nc2ccccc2s1 +CCC(CC)C(O)CNC(=O)c1cncc(Br)c1 +COc1ccc(OC)c(-c2csc(NC(=O)C3CC3)n2)c1 +CCC(=O)NC1CCCN(C(=O)NCCCc2cccc(F)c2)C1 +CN1CCc2[nH]nc(-c3cccc(Cl)c3Cl)c2C1 +COc1ccc(C)cc1-c1csc2nc(C)[nH]c(=O)c12 +Cc1nc(C2CCCN2C(=O)CCCn2cccn2)no1 +COc1ccncc1NC(=O)c1ccccc1OC(C)C +O=C1OCC(c2ccccc2)N1Cc1nnc(C2CC2)o1 +CCS(=O)c1ccccc1C(=O)NC1CCc2c(Cl)cccc21 +COc1ccc(NC(=O)CSc2ccc3nncn3n2)c(OC)c1 +CN(CCC1CCCCC1)C(=O)c1ccc(S(C)(=O)=O)cc1 +CC(=O)c1cc(C(=O)Nc2ccc3c(c2)OC(F)(F)O3)n(C)c1 +O=C(C1CCOCC1)N1CCCC(c2n[nH]c3nccnc23)C1 +CCNC(=O)CNC(=O)Nc1cccc(Cl)c1Oc1cccnc1 +Cc1nn2cc(C(=O)NCCc3ccccn3)nc2s1 +CC(C)CS(=O)(=O)N1CC2CC(C(=O)N(C)C)C(C1)O2 +CCN(CC)C(=O)C1CCN(Cc2cnc(CC(C)C)s2)CC1 +COC(=O)c1ccc(NC(=O)CS(=O)(=O)c2ccc(C)cc2)cc1 +O=C(Nc1cc(F)c(F)c(F)c1)c1ccnnc1 +O=C(c1ccc(F)cc1)N1CCOc2ccc(F)cc21 +CCOC(=O)CN(C)C(=O)Cn1nnc2ccccc2c1=O +Cc1c(Cl)c(C(O)C(C)(C)C)cc2c1NC(=O)C2C +O=C(NCc1noc(C2CCCC2)n1)c1cc(C2CC2)n[nH]1 +Cc1cccc(C(=O)NCCC2CNc3ccccc32)c1C +CSc1ccc(CNC(=O)NCC(=O)NC(C)C)cc1 +O=C1CCCN1Cc1ccc(NCc2ccc3c(c2)OCCO3)cc1 +CC1CC(c2ccccc2)=Nc2ccccc2S1(=O)=O +Cc1n[nH]c(C)c1NC(=O)Nc1ccc2c(c1)C(=O)N(C)CC2 +c1ccc(-c2c[nH]c(SCc3nc(-c4ccco4)no3)n2)cc1 +COc1ccccc1C(C)NC(=O)NCc1c(C)noc1C +O=C(Nc1ccc2c3c(cccc13)CC2)N1CCC(n2cncn2)CC1 +CN(C)c1ccc(-c2nnc(-c3ccoc3)o2)cc1 +CC(NCC(=O)N1CCOCC1)c1ccc(-c2cccnc2)cc1 +CC(C)NC(=O)CCC(O)c1ccc(Cl)cc1 +Cc1cc(O)ccc1-n1nnc(-c2cccs2)c1N +Cn1nc(-c2ccc(F)cc2)cc1C(=O)NCCn1ccnc1 +O=C(c1ccc(F)c(F)c1)N1CCN(c2ncnc3[nH]ccc23)CC1 +COc1ccc2c(c1)OCC(C(=O)N(C)Cc1ccsc1)C2 +CCNC(=O)C(C)NC(=O)Nc1ccccc1OC +NC(=O)c1ccc(C(=O)N2CCCc3cc(C(F)(F)F)ccc32)nc1 +CCCS(=O)(=O)NC1CCN(c2c(F)cc(C#N)cc2F)CC1 +CC(C)(C)C(=O)Nc1nnc(Cc2cccs2)o1 +CCOC(=O)C1CCCN(C(=O)Cc2c[nH]c3ccccc23)C1 +Cc1cn(C2OC3(CO)C(C)OC2C3O)c(=O)[nH]c1=O +CC1CCCC(NS(=O)(=O)c2ccc(F)cc2F)C1 +C=C(C)COc1cccc(NC(=O)NCc2ncn(C)n2)c1 +CCCNc1nnc(SCc2nc3ccsc3c(=O)[nH]2)s1 +CC(C(=O)NCCc1cccs1)N1CCn2c(nn(C)c2=O)C1 +Cc1nnsc1C(=O)Nc1ccc2c(c1)N(C(=O)C1CC1)CC2 +CCCN1CC(CC)Oc2ccc(C(=O)C(C)N)cc21 +O=C(COc1ccc2ccc(=O)oc2c1)Nc1cccc2cccnc12 +O=C(NCCNC(=O)c1cccnc1)NCc1cccnc1 +COc1ccccc1-c1nc2cc(C(C)=O)ccc2[nH]1 +Cc1cc(S(C)(=O)=O)c(C)c(S(=O)(=O)Nc2c[nH]nc2C)c1 +CN(C)S(=O)(=O)N1CCC(C(=O)Nc2c(F)cccc2F)CC1 +O=C(Nc1cccc(F)c1F)c1cccc(OCC(F)F)n1 +CCN(CCC#N)S(=O)(=O)c1ccc(F)cc1C(F)(F)F +Cc1ccccc1CN(C)C(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +Cc1ccc(F)c(NC(=O)NCc2cnn(C)c2)c1 +Cc1nn(-c2ccc(F)cc2)c(C)c1CC(=O)N1CCC(O)C1 +O=C(CCS(=O)(=O)c1ccc2c(c1)OCCO2)Nc1ccccc1 +Cc1nc2ccccc2c(=O)n1CCNC(=O)c1ccc2[nH]ccc2c1 +COCCN(CCOC)C(=O)c1cc(Cl)ccc1Cl +Cc1ccc(C(=O)NCC(=O)N2CCN(C(C#N)C(C)C)CC2)cc1 +CC(C)(C)CC(NC(=O)Cn1cnnn1)c1ccc(F)cc1 +OC(c1ccccc1)C(F)(F)c1cnc2ccccn12 +CC(=O)NC(C(=O)NCC(O)c1ccco1)C1CCCC1 +CCOCCCn1c(C)nc2cncc(Br)c21 +CCC(CC#N)NC(=O)Nc1cccc(N(C)C(C)C)c1 +CCn1ccnc1N1CCN(C(=O)c2ccc(C)cc2)CC1 +CS(=O)(=O)c1cccc(OC(=O)CCc2ccsc2)c1 +CC(Oc1cccc(C#N)c1)C(=O)Oc1cccc(C(=O)N(C)C)c1 +CC(=O)NCC(=O)NC(C)c1ccc(OC(F)(F)F)cc1 +COCCNC(=O)CCCn1nc(C)c2c(C)onc2c1=O +CC1CCN(C(=O)c2cccn2-c2nnc(N3CCCC3)s2)CC1 +Cn1cnnc1-c1cccc(NC(=O)c2csc3c2CCCC3)c1 +CCCCn1c(COC(C)=O)nc2cc(S(N)(=O)=O)ccc21 +CC(=O)N1CCCC(C(=O)N2c3ccccc3CC2C)C1 +Cc1nc2nncn2c(Nc2ccc3c(c2)CCC3)c1C +O=C(CCCc1cccs1)Nc1ccccc1O +Cc1nn(CC(F)(F)F)c(C)c1C1C=CC(O)C1 +Cc1[nH]c(=O)c(C(=O)Nc2ccccc2C#N)c(C)c1N +Cc1cccc2c1NC1(NC2=O)C(=O)Nc2cc(O)ccc21 +CN(C)C(=O)COc1ccc(Br)cc1Cl +COc1ccc2c(Cn3cnc(C#N)c3C#N)cc(=O)oc2c1 +Cc1cccc(C(CO)Cc2ccc3c(c2)OCCO3)c1 +Cc1ccc(C(O)CCC(=O)NCCC(C)C)cc1C +COc1cc2ccncc2cc1OCC(=O)NCC(F)(F)F +CN1CCC(C(=O)NCc2cccc(Cn3ccnc3)c2)CC1=O +Nc1cc(C(=O)Nc2ccc3nc[nH]c3c2)ccc1Cl +CCCCn1ncc(NC(=O)NCc2ncc[nH]2)c1C +CCc1ccc2ncnc(N(C)CCc3ccncc3)c2c1 +Fc1ccc(NCc2ccc(-n3ccnc3)cc2)cc1Br +Cc1ccc(CNC(=O)C2CC(=O)N(Cc3ccccn3)C2)cc1F +COC(=O)CCCNC(=O)C(N)c1ccc(N)cc1 +N#Cc1cnn(C(=O)c2ccc(F)cc2Cl)c1N +O=S(=O)(c1ccc(O)cc1)c1ccc(F)cc1 +Cc1nc(CSc2n[nH]c(=O)n2CCc2ccccc2)oc1C +Cc1ccccc1S(=O)(=O)CC(=O)N1CCCC(C)C1 +COc1ccccc1NC(C)c1nc(C2CC2)no1 +CNC(=O)NCC(=O)Nc1cccc(COc2ccccc2)c1C +O=C(NCCSc1nc2ccccc2o1)C1CCOC1 +COc1ccccc1OC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +CC(CO)(NC(=O)Nc1cc(Br)ccc1F)C1CC1 +COc1cc2nc(C#N)cc(N3CCCCC3)c2cc1OC +Cc1cc(Cl)ccc1OC(=O)CCCCNC(N)=O +COc1ccc(COC(=O)c2ccc(C)c(NC(C)=O)c2)cc1 +O=C(Nc1nc2ccccc2nc1N1CCCC1)C1CC2CCC1O2 +O=C(c1cnn2c1OCCC2)N1CCN(Cc2ccccc2)CC1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccc(Oc2ccccc2)nc1 +Cc1noc(C2CCOC3CCN(C(=O)c4ccsc4)CC32)n1 +O=C(NC1CC1)c1c(F)c(F)c(F)c(F)c1F +N#Cc1cc(-c2ccc(C(F)(F)F)cc2)oc1N +CC(C)OC(=O)c1cccc(Cn2cc(N)ccc2=O)c1 +Cn1cc(C(=O)Nc2cccc3c2ccn3C)c2ccccc2c1=O +COC(=O)c1ccccc1NC(=O)c1ccc2c(c1)OCCO2 +COc1cc(-c2ncnn2-c2ccc(Cl)cc2)cc(OC)c1OC +CC(=O)NCCc1nc2ccccc2n1CC(=O)N1CCCCC1 +COCCOc1cccc(NCc2ccc(C#N)cc2F)c1 +CC(O)C(=O)N1CCc2c(nc(-c3ccccc3)nc2N(C)C)C1 +c1cc(OCc2ccc3c(c2)OCCO3)cc(-n2cncn2)c1 +O=C(CSc1ncc2ccccn12)N1CCc2sccc2C1 +Cn1cc(C2(C)CN(C(=O)Cc3ccccc3O)CCO2)cn1 +Cc1cc(C)c(C(=O)NCCSc2ccccc2)c(=O)[nH]1 +CN(Cc1ccccn1)c1ncnc2ccsc12 +COc1ccc2c(CC(=O)Nc3nnc(CC(C)C)s3)coc2c1 +CC1COCCN1C(=O)CCCc1nc(-c2ccc(Cl)cc2)no1 +COc1ccc(OC)c(N2Cc3ccc(N)cc3C2=O)c1 +COc1cc(NC(C)=O)ccc1NC(=O)N1CC(C)CCC1C +Cn1nc(CC(C)(C)C)cc1NC(=O)COCC1CCCO1 +CCCOC(=O)C(C)n1c(CC(C)C)nc2c(N)cccc21 +O=C(Nc1ccccc1F)c1cc2cccnc2[nH]c1=O +COc1nccnc1NC1CCN(C(=O)c2cnccn2)CC1 +CC(C)c1noc(CCC(=O)Nc2ccccc2Cl)n1 +N#Cc1cccc(OCc2nc(-c3ccco3)no2)c1 +CCC(CC)NC(=O)Cn1nnnc1C1CCCCC1 +Cc1noc(C)c1COc1ccc(CC(=O)N2CCOCC2C)cc1 +COCc1nn(C)c2c1CN(C(=O)Cc1c[nH]c3ccccc13)CC2 +O=C(c1c[nH]cn1)N1CCC2C1CC(=O)N2c1cccnc1 +CCCOc1nc(C2CC2)nc(NCc2ccccn2)c1N +Cc1nc2cc(C(=O)NCc3ccc(Cl)cc3)ccc2n(C)c1=O +O=C(NCC(F)(F)F)c1ccc(NC(=O)c2ccc[nH]c2=O)cc1 +COc1ccc(-c2cc(=O)n(CCNC(=O)C3CCC3)cn2)cc1 +CNC(=O)c1cccc(CNc2cc(F)cc(F)c2)c1 +CCOC(=O)c1c(C)[nH]c(C(=O)N(C)C2CCc3ccccc32)c1C +CC(C)NC(=O)Nc1ccc(OC(F)F)cc1OC(F)F +O=C1CC(c2cccnc2)C2(CCN(C(=O)c3cscn3)CC2)N1 +COc1ccc(C2(C#N)Cc3ccccc3C2)cc1OC +N#Cc1cccc(C(=O)Nc2sccc2C(=O)NC2CC2)c1 +CCOc1cccc(C2CC(=O)Nc3cc(OC)cc(OC)c32)c1 +Cc1ccc(S(=O)CC2CCN(C(=O)OC(C)(C)C)C2)c(C)c1 +CCCNC(=O)CNC(=O)C1(c2ccc(F)cc2F)CCOCC1 +CNc1ncc(C(=O)NCCOCc2ccc(Cl)cc2)cn1 +O=C1CN(c2ccccc2NC(=O)Cc2ccc(F)cc2)CCN1 +CC(CC#N)N(C)C(=O)c1cc(-c2cccc(Cl)c2)no1 +COc1c(Br)cccc1CCNC(=O)CCNC(N)=O +Cn1cc(C(=O)OCCc2cn[nH]c2)c(-c2cccs2)n1 +O=S1(=O)N=C(NCc2ccncc2)Nc2ccccc21 +CCC(C)(C)NC(=O)CSc1nc(C2CCCO2)n[nH]1 +NS(=O)(=O)c1ccc(CNC(=O)c2ccccc2)s1 +Cc1cc(NC(=O)Cc2ccc(-n3cccc3)cc2)n(C)n1 +COc1ccc(OCCNC(=O)NCc2ncn(C)n2)cc1 +CCC(C)NC(=O)CSc1nnnn1C(C)C +CCc1cnc(COC(=O)c2cc(C(C)=O)cs2)s1 +COc1ccc(-c2noc(-c3cnc4ccc(C)cn34)n2)cn1 +Cc1noc(C)c1-c1ccc(S(=O)(=O)NCc2ccco2)cc1 +C=CCN(Cc1cnc(C2CC2)s1)Cc1ccccc1F +O=S1(=O)CCCN1c1ccc2c(c1)CCCN2 +Cc1cc(NCc2nncn2C(C)C)nc(-c2ccncc2)n1 +Cn1cccc1C(=O)NC(Cn1cncn1)c1ccccc1 +O=C1CCN(Cc2ccccc2Br)CCN1 +Cc1sc(NC(=O)C2CCC2)c(C(N)=O)c1C +CC(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)Nc1ccc(Cl)cn1 +Cc1ccc(-c2ccc(C(=O)OCC3CCC(=O)N3)s2)o1 +NC(=O)c1nc(C(=O)NCc2ccc(F)cc2)cs1 +CCOC(C)c1noc(CNc2nccnc2C#N)n1 +CCOC(=O)c1ccc(NC(=O)c2ccc(C#N)cc2)cc1 +Cc1cc(CN(C)C(=O)c2ccc(-c3ccccc3)[nH]c2=O)no1 +O=C(CCNC(=O)C1CCC(F)(F)CC1)NCc1ccccn1 +COC(=O)c1cc2nc3c(c(C)c2n1C)C(=O)CC(C)(C)C3 +Cc1ccc(O)c(C(=O)c2cnn(C(=O)COc3cc(C)on3)c2)c1 +C=CCc1ccccc1OCC(O)Cn1cnc2ccccc2c1=O +Cc1cc(C)c(NC(=O)c2cnc3n(c2=O)CCS3)c(C)c1 +O=C(CNC(=O)NCc1ccc(F)cc1)Nc1ccccn1 +Fc1ncc(Br)cc1Br +Cc1cccc(OCCCn2nnc(C#N)c2-c2ccncc2)c1 +N#CCc1ccccc1C(=O)OCCc1ccccc1 +CCCC(C)C(=O)Nc1cc(C(=O)OC)c(F)cc1F +COc1ccc(S(=O)(=O)N2CC(C)C(O)(C3CCC3)C2)cc1 +COCCNc1ncnc2c1cnn2Cc1ccc(C)cc1 +COc1ccc(NC(=O)NCc2cnn3ccccc23)cc1 +C#Cc1cc(F)c(NC(=O)N2CCOC(C)C2C)c(F)c1 +COc1ccccc1CNC(=O)CCNC(=O)c1ccccc1Cl +CC(=O)NC(C)C(=O)Nc1cccc(NC(=O)c2cccs2)c1 +COC(=O)c1cc(Br)c(OC)c(OC)c1 +CCc1ccc(C(=O)Nc2ccc(S(C)(=O)=O)cc2C)cc1 +Cc1ccc2c(n1)OCCN2C(=O)C1COc2ccccc21 +Cc1ccc(NC(=O)NCC2(O)CCOc3ccccc32)cc1 +COC(=O)CCSc1nnc(Nc2ccccc2)s1 +Cc1cccc(C(=O)n2nnc3ccccc32)c1O +O=C(c1cccc(-c2ncc[nH]2)c1)N1CCC(F)(F)CC1 +COc1cc2c(cc1Br)CCNC2C1CCC1 +Cc1cc(Br)ccc1NS(C)(=O)=O +COC(=O)N1CCC(NC(=O)c2cc3cccc(OC)c3o2)CC1 +C=CCNC(=O)C1CSc2cc(N)ccc2O1 +CCCn1cc(O)c(=O)cc1CN(CC)Cc1ccccc1 +Cc1cc(NC(=O)COc2cccc(N3CCCC3=O)c2)no1 +CCOCCC(=O)Nc1ccc(C#CCO)cc1C +Cc1ccccc1Cn1c(NCCO)nc2c1c(=O)n(C)c(=O)n2C +Fc1ccc(-c2[nH]ncc2-c2nnnn2-c2ccccc2)c(F)c1 +C=CCNS(=O)(=O)c1ccc(OC)c(Cl)c1 +Cc1nc(N2CCOCC2)c2c3c(sc2n1)CC(C)CC3 +CCCn1c(SC(C)C(N)=O)nc2cc(Cl)ccc21 +O=C(NCCc1cccs1)c1ccc2ccccc2n1 +Cc1cc(-c2cc(Cl)ccc2Cl)nc(N)n1 +CC(C)(C)CC(=O)NCC(=O)Nc1ccc(F)cc1F +COc1cc2c(cc1OC)CN(C(=O)NCCN1CCOCC1)CC2 +NC(=O)CCSc1ccccc1NC(=O)c1ccc(F)nc1 +CCS(=O)(=O)NCCNC(=O)c1ccc(F)cc1Cl +CCn1nnc(CO)c1COc1ccccc1Cl +CCCS(=O)(=O)NCCN1CCN(c2ccc(F)cc2)CC1 +COCc1cccc(S(=O)(=O)NCCN2CCOCC2)c1 +CCOC(=O)C1CN(S(=O)(=O)CC)Cc2ncn(CC)c21 +CCOc1nc(C2CC2)nc(NCc2ccccc2F)c1N +Cc1cnccc1CCNC(=O)NCc1cn(C)nc1-c1ccccc1 +CN(Cc1ccc(C(N)=O)cc1)C(=O)C(C)(C)C#N +C=CCNC(=O)NCC(c1cccc(Cl)c1)N1CCOCC1 +O=C(c1ccc(O)c(Cl)c1)N1CCOCC1C1CC1 +COc1ccc(N2CC(c3nnc(N)o3)CC2=O)cc1 +CCOC(=O)c1ncccc1NC(=O)COc1ccccc1Cl +Cc1ncc(CNC(=O)c2ccc(NC(=O)c3ccco3)s2)s1 +Cc1cc(NC(=O)c2cc(-c3cccs3)on2)n(CCC#N)n1 +CCN(C(=O)CCc1ncc(-c2ccccc2)o1)C(C)c1ccncc1 +COc1ccc2c(c1OC)C(=O)OC2CC(=O)c1ccc(O)cc1O +Cc1ccc(-c2nsc(C(=O)N3CCC(C)CC3)c2N)cc1 +COc1ccccc1-n1nc(C2CC2)nc1CNC(=O)c1ccccc1 +Cn1ncc(-c2cccc(F)c2)c(C(N)c2ccccc2)c1=O +Cc1ccc(-c2ncco2)cc1NC(=O)N1CCC(O)C1 +Cc1ccc(C)c(C(=O)Nc2cc(N)ccc2Cl)c1 +O=C(OCCn1cccn1)c1cccc(C(F)(F)F)c1F +COC(=O)c1ccsc1NC(=O)CCc1cnn(C)c1 +Cc1noc(C2CCCN(C(=O)CCc3nccs3)C2)n1 +CC(=O)c1sc(N(C)C)nc1-c1cccs1 +COCC1CCCN(C(=O)NCC2CN3CCCCC3CO2)C1 +O=C(C1CC1)N1CC(F)C(OCc2nc3ccc(F)cc3[nH]2)C1 +CC1CN(C(=O)CNc2ccc(F)c(Cl)c2)CC(C)O1 +C=CCSc1c(CC(C)C)cnc2c1c(=O)n(C)c(=O)n2C +Cc1ccsc1C(=O)NCc1ccccc1-n1cccn1 +Cc1cccc(N2CCN(C(=O)c3c(C)c(C)n[nH]c3=O)CC2)c1C +C=CCNc1nnc(SCC(=O)NC2CCCCC2)s1 +CNC(=O)c1ccc(CN(C(=O)c2cc3ccccc3o2)C2CC2)cc1 +O=C(NCCC(=O)N1CCCCC1)Nc1cccc(F)c1 +Cc1ccccc1NC(=O)NCCOCC(F)(F)F +CCCC(C)(NS(=O)(=O)c1ccc(F)cc1)C(=O)OC +CC(CCCO)NC(=O)NC(C)C(=O)NC(C)(C)C +CN(CC(C)(C)C)C(=O)c1c[nH]c2cccc(F)c12 +O=C(NCC1(CO)CC1)NC1CCCN(Cc2ccccc2)C1=O +CC(=O)c1ccccc1NC(=O)c1ccnc(F)c1 +Cc1nn(C)c(C)c1OC(=O)CCCn1ccc2cc(Cl)ccc21 +CCNC(=O)c1cccc(NC(=O)c2cccc(Cl)c2)c1 +Cc1cc(C)n(C2CN(C(=O)C3COc4ccccc4C3)C2)n1 +N#Cc1ccccc1C(=O)NCc1csc(=O)[nH]1 +COc1cc(C)c(C(C)NC(=O)Nc2c(C)n[nH]c2C)cc1OC +CN(Cc1ccncc1)C(=O)C(C)(C)c1cccc(Cl)c1 +CCc1nc2n(n1)CCCC2NC(=O)NCCCN1CCOCC1 +OCCN(c1ncc(Cl)cc1Cl)C1CCCC1 +CCOc1ccc(-n2ccc(=O)c(C(=O)Nc3ccccc3C)n2)cc1 +Cn1cc(C(=O)Nc2ccc(O)cc2)c(C(C)(C)C)n1 +CC(C)Cc1ccc(C(=O)CCC(=O)N2CCOC(C(N)=O)C2)cc1 +O=C(Nc1nc2ccccc2s1)c1cc2ccccc2oc1=O +NC(=O)COC(=O)c1ccc(COc2ccccc2)cc1 +COCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +CCCCN(CCO)S(=O)(=O)c1cnc2ccsc2c1 +COC(=O)c1cccc(NC(=O)c2cc(F)cc(F)c2)c1 +CC(=O)Nc1cccc(NCc2cc(C#N)ccc2F)c1 +NC(c1nc2c(s1)CCC2)c1c(F)cccc1F +COc1cc(NC(=O)CC2C=CCC2)cc(OC)c1 +Cc1ccc2c(c1)N(C(=O)c1ccncc1)CC(C)O2 +Cc1nc(COC2COC3(CCN(c4cncnc4)CC3)C2)cs1 +Cc1nc2c(s1)C(N(C)C(=O)c1nccnc1N)CCC2 +Cc1cccc2c1C(C(=O)N1CCOCC1)CC2=O +CC(Cn1cncn1)NC(=O)Nc1cccc(C#Cc2ccccn2)c1 +CCCCCNC(=O)CCC1C(=O)N=c2c(c(C)nn2C)=C1C +O=C(NCCOc1cccc2ccccc12)NC1CC1 +O=C(Nc1cc(Cl)ccc1O)c1cccc(-n2ccnc2)n1 +Nc1cccc2c(C(=O)Nc3ccc4cn[nH]c4c3)nccc12 +Cc1nc(CNC(=O)NC(C)c2ccc3c(c2)OCCCO3)cs1 +COc1cccc(NC(=O)c2cccc(N)c2C)c1 +NC(=O)CN(C(=O)CC1C=CCC1)c1ccccc1 +COc1ccc(COC(=O)Oc2ccc(C#N)cc2)cc1OC +CC(C)OCc1cccc(CNC(=O)c2ccncc2)c1 +CC(C)(C)NC(=O)CNc1ncnc2c1cnn2-c1ccc(F)cc1 +O=C(CC1CC1)N1CCC2(CCC(=O)N2Cc2cccnc2)CC1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(OC(F)F)cc2)c1C +Nc1cnn(Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c1 +CCC(=O)Nc1ccccc1OCc1cc(=O)n2ccc(C)cc2n1 +Cc1cccc(C2(C(=O)Nc3ncc(C)s3)CC2)c1 +Cc1csc(NC(=O)Nc2cnn(C)c2C(F)F)n1 +CCC(=O)N(CC(C)C)c1c(N)n(CC(C)C)c(=O)[nH]c1=O +COc1ccc(-c2ccc(SCc3ccccn3)nn2)cc1OC +N#CCc1ccccc1C(=O)N1CCCCC1CCO +COc1ccc(C(=O)N2CCc3c([nH]c4ccnn4c3=O)C2)cc1F +O=C(Nc1ncccn1)c1ccc(Oc2ccccc2)cc1 +CCOc1ccc(NC(=O)C2CCN(S(=O)(=O)CC)CC2)cc1 +Cc1ccc(NC(=O)c2cccnc2N2CCOCC2)cc1 +COc1ccc(-c2nnc(NC(=O)c3cccc(C)c3)o2)cc1OC +CC(C)Cc1ccc(CC(=O)N2CCC(=O)CC2)cc1 +COc1cc2ncn(CC(=O)NC(C)C)c(=O)c2cc1OC +C=CCNC(=O)CSc1nc(-c2ccc(Cl)cc2)n[nH]1 +COc1cccc(CC(=O)N2CCC(Oc3ccc(C)nn3)CC2)c1 +NC(=O)CSc1nc2ccccc2n1CCO +COc1ccc(C(O)CCCC(=O)N(C)c2ccccc2)cc1 +Cc1ccc(C(=O)OCc2c(C#N)c(C)nn2-c2ccccc2)c(=O)[nH]1 +Cc1ccc(C(=O)NCCNS(C)(=O)=O)c(O)c1 +O=C(CSc1nncn1-c1ccccc1)N1CCCCC1 +CCn1cc(Cn2ccnc2-c2cc3ccccc3nc2OC)cn1 +CN(Cc1ccccc1F)S(=O)(=O)c1c[nH]nc1N +CNC(=O)Cn1cc(NC(=O)C(C)n2ccnc2)cn1 +Cc1ccc(F)c2c1N(C(=O)CCc1cnn(C)c1C)CCC2 +CC(=O)Nc1cc(NCc2sc(C)nc2C)ccc1Cl +COc1cccc(C(N)c2nc(-c3cccc(Cl)c3)n[nH]2)c1 +CNC(=O)CNC(=O)c1cc2occc2n1Cc1cccc(F)c1 +Cc1noc(C(C)NC(=O)Nc2cc(Cl)ccc2Cl)n1 +CCC(=O)NC1CCCN(c2ccc(Br)cn2)C1 +Cc1ccnc(NC(=O)c2cc(S(=O)(=O)N(C)C)cs2)c1 +Cc1nc(C(=O)NCc2ccccc2F)nn1-c1ccc(F)cc1 +O=C(COc1cccc(F)c1)N1CCN(CCO)CC1 +CC(C)Oc1ncc(C(=O)N2CC(C(N)=O)CCC2C)cc1Cl +c1ccc(Cn2nnnc2CN2CCN(c3ncccn3)CC2)cc1 +CC(=O)c1ccc(NC(=O)c2cccnc2-n2cccn2)cc1C +Cc1cccc(C(=O)N(C)Cc2nc(-c3cccc(C)c3)no2)c1 +O=C1CC(CNc2nnc(C3CC3)s2)c2ccccc2N1 +N#CC1(C(=O)NCCOCCO)CCCCCC1 +CC(C)NC(=O)CNC(=O)CCCc1ccc(Cl)cc1 +Cc1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)C2)c(C)c1 +C#CCOC(=O)CCCC(=O)Nc1ccc(Cl)cc1 +CCOc1ccc(NC(=O)c2ccc3[nH]c(C)cc(=O)c3c2)cc1 +Cc1ccc(C(N)=O)c(OCc2cc(=O)n3ccc(C)cc3n2)c1 +CC(C)Cn1c(C(C)NC(=O)c2ccncc2)nc2ccccc21 +CNC(=O)COCc1cc(-c2ccc(F)cc2)on1 +Cc1ncc2c(n1)CCN(C(=O)Nc1ccc(Br)cc1)C2 +CN(Cc1ccc(C#N)cc1)Cc1nnc(C2CC2)o1 +Fc1cnc(N2CCCC(c3ccn[nH]3)C2)nc1N1CCOCC1 +N#CCn1c(-c2cccs2)nc2cc(Cl)cnc21 +CCc1noc(CC)c1CC(=O)N(C)Cc1ccccc1C +COc1cc(OC)cc(C(=O)N2CCN(Cc3ccncc3)CC2)c1 +Clc1ccccc1OCc1nc(-c2cccnc2)no1 +CC(=O)c1c(C)nn(Cc2nc(-c3ccccc3)nn2CCO)c1C +O=C(NCCCNc1ccc(C(F)(F)F)cn1)c1ccc[nH]c1=O +CCc1nc2n(n1)CCCC2NC(=O)CC(C)c1cccc(OC)c1 +CCCc1nnsc1C(=O)NCC(OC)c1ccccc1C +O=C(Cc1ccc[nH]1)N1CCN(C(=O)c2ccccc2)CC1 +COc1ccccc1Cn1c(C)nc2ccccc21 +Cc1ccc(CN(C(=O)c2cccc(C#N)c2)C2CC2)cc1 +COC(=O)CNC(=O)Cn1cc(C(F)(F)F)ccc1=O +Cc1cc(=O)c(C(=O)NCC(N)=O)nn1-c1ccccc1 +CN(C)C(=O)CSc1nnnn1-c1ccc(Cl)cc1 +CCOc1ccc(C(C#N)N(C)C(=O)CC(C)C)cc1 +CC1CC1c1ccc(CN2CCOC(C(N)=O)C2)o1 +COc1ccc(CN(C(=O)CSc2nncs2)C2CC2)cc1 +CCCOC(=O)c1cccc(Cn2c(C)ccc(C#N)c2=O)c1 +CCCC(=O)N1CCC(C(=O)Nc2cccc(C)c2C(N)=O)CC1 +O=C(c1ccc(F)cc1F)N1CCC(C(O)Cc2ccccc2)CC1 +CN1CC(C(=O)Nc2ccc(NC(=O)OC(C)(C)C)nc2)CC1=O +O=C1CN(C(=O)CNc2ccc(Cl)c(Br)c2)CCN1 +CCN(CC)C(=O)Cc1ccc(NC(=O)C(C)NC(C)=O)cc1 +OCCNc1cc(N2CCOC(c3ccc(Cl)cc3)C2)ncn1 +CC(C)n1ccc(-c2nnc(NC(=O)c3c(F)cccc3Cl)o2)n1 +O=C(COc1cccc(Cl)c1)Nc1cccc2nonc12 +N#CCOc1cccc(CC(=O)Nc2ccccc2N2CCCC2=O)c1 +COc1cccc(CC(=O)Nc2nc(C)c(C)s2)c1 +COc1cccc(CN2CC(n3cc(C)cn3)C2)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)C1Cc2cc(F)ccc2O1 +COc1ccc(CCNC(=O)c2ccc(Nc3ncccn3)cc2)cc1 +Cn1cccc(NC(=O)CCc2cccc(Cl)c2)c1=O +CCOc1cccc2cc(-c3cc(C(=O)OC)[nH]n3)oc12 +c1ccc2c(-c3nc(C4CC4)n[nH]3)cc(-c3ccncc3)nc2c1 +Nc1nnc(SCc2cccc(Br)c2)n1C1CC1 +CCCCCn1c(C(F)(F)F)ccc(C(N)=O)c1=O +CCc1ccsc1C(=O)NCCC(=O)N1CCCCC1 +C=CCc1cc(C(=O)Nc2ccc(OC)nc2)cc(OC)c1OC +NC(=O)CCCNC(=O)COc1ccc(F)c(Cl)c1 +OCc1nnn(-c2ccc(Cl)cc2)c1-c1cccc(F)c1 +CCCS(=O)(=O)c1nsc(C(=O)NC(C)(C)C)c1N +CN(C)S(=O)(=O)c1ccc(OC(=O)c2cccn2C)cc1 +CCC(C)(C)C1CCC(O)(Cc2cnn(C)c2)CC1 +Cc1cc(C(=O)Nc2ccc(F)c(F)c2)c(C)s1 +COc1ccc(OC)c(NCC(O)c2cccs2)c1 +Cn1cc(NC(=O)CCOc2ccccc2Cl)cn1 +CCCc1cc(=O)[nH]c(SC2CCCCNC2=O)n1 +CC(C)N(CC(N)=O)c1ccc(N)c(C(F)(F)F)c1 +COc1ccc2c(c1)C(CC(=O)N1CCN(C)CC1)CC2=O +C#CCCNC(=O)C1CCN(S(C)(=O)=O)CC1 +CCOc1cc(Br)ccc1C(=O)NC1CC1 +Cc1cc(NC(=O)c2sccc2C)c2ncccc2c1 +CS(=O)(=O)N1CCC(C(=O)Oc2cccc(-n3cccn3)c2)CC1 +Cc1cc(C)nc(NCCNc2ncccc2C#N)n1 +CCCc1cc(C(=O)N(C)CCOc2ccccc2)[nH]n1 +O=C(C1COc2ccccc2C1)N1CCC(N2CCNC2=O)CC1 +CC1(C)CC(NC(=O)CC(O)(c2ccccc2)C(F)(F)F)CCO1 +Cc1ccc(OCCN(C)c2c(C#N)c(=O)n(C)c(=O)n2C)cc1 +CCCCN(C)C(=O)COc1coc(CO)cc1=O +Cc1cc(CN2CCN(CC(F)(F)C(F)F)CC2)c(C)o1 +CCNC(=O)C(C)NC(=O)Cc1cc(C(C)=O)ccc1OC +COc1cccc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)c1F +CCOc1ccc(NC(=O)COc2cccnc2N)cc1 +Cc1ccccc1CN(C)C(=O)COc1ccc(F)cc1F +COCCNC(=O)CNC(=O)c1ccc(F)cc1F +O=C(Nc1cccn(Cc2ccccc2)c1=O)C1CC=CCC1 +Cc1ccc2cccc(OCc3nnc(C(C)(C)C)o3)c2n1 +O=C(COC(=O)c1cc(=O)[nH]c2ccccc12)c1ccccc1Cl +COc1ccc(NC(=O)c2csnn2)cc1OC1CCCC1 +CCOC(=O)c1nccn1Cc1c(F)cccc1Cl +C=CCN(CC1CCCCC1)C(=O)c1ccc(F)nc1 +CC(C)C(=O)NCCN(C)C(=O)Nc1ccc(F)c(C(F)(F)F)c1 +COc1ccc2c(c1)nc(CO)n2CC(=O)N1CCCC1 +Cc1cc(C)n2c(CNC(=O)c3ccc(F)cc3)nnc2n1 +CC(C)(C)OC(=O)NCC1(NC(=O)C2CCOCC2)CCCC1 +CCOc1ccc2nc(SCC(=O)Nc3nonc3C)[nH]c2c1 +Cc1ccc(Cl)cc1N1CCC(CNC(=O)C(C)n2cncn2)C1 +CCOC(=O)c1nc(N)nc2c1NC(C)C(C)N2 +Cc1nn(C)c(C)c1C(C)NC(=O)c1cc(Cl)cn1C +CN(CCCN1CCOCC1)Cc1ccc2c(c1)OCO2 +CC(NC(=O)C1CCCN1C(=O)OC(C)(C)C)c1ccccc1 +Cc1cc(C)cc(NC(=O)c2cc(C(N)=O)cs2)c1 +NC(c1cccs1)c1nnc2sc3c(n12)CCCC3 +CNC(=O)c1ccc(Cl)cc1NC(=O)c1cccc(C)c1 +COCCN(Cc1ccccc1)Cc1csc(C)n1 +Cc1c(N)ccc(Br)c1Br +Cc1ccc(C(C)OC(=O)c2cccc(C)n2)cc1 +Cn1cnc(CNS(=O)(=O)Cc2ccccc2)n1 +CCOc1cc(C)c(C(=O)N2CCC(=O)CC2)cc1C +C=CCNC(=O)NCc1ccc(Oc2cccnc2)c(F)c1 +CC1CN(c2ccccc2)C(=O)CN1C(=O)Cn1nc2ccccc2n1 +Cc1cccc(C)c1NC(=O)CCC(=O)Nc1nccs1 +Cn1cnnc1C1CCCN(C(=O)NCc2ccccc2)C1 +CNC(=O)c1ccccc1C#CCNC(=O)Nc1ccccc1 +O=C(Nc1cccc2c1CCCC2)C(O)c1ccccc1 +CCn1nc(C2CCOCC2)nc1-c1ccc(-n2cnnc2)cc1 +Cc1ccc(CCOC(=O)C2(C)CCOCC2)cc1 +CCOC(=O)CCC(C)NC(=O)c1cc(C)nc2c1cnn2C +Cc1oc(-c2ccccc2)nc1CSc1nnc(N)[nH]1 +CC(=O)Nc1ccccc1-c1nc(-c2ccccc2)no1 +CC(C)C(C#N)N1CCN(C(=O)c2ccc(-n3ccnn3)cc2)CC1 +COc1cc2ccc(=O)oc2c(O)c1OCC=C(C)C +CCN(Cc1cnc2ccccn12)C(=O)Cc1cccc(C)c1 +CCOC(=O)C(N)Cc1nc2cc(Cl)ccc2n1C +CCN(C(=O)CSc1nnc(C)n1N)C(C)c1ccc(F)cc1 +CC(N(C)C(=O)Nc1ccc2c(c1)COC2)C1(C)CC1 +C=CCNC(=O)C1(NC(=O)c2ncoc2-c2ccco2)CCCCC1 +CN(CCc1ccccc1)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +O=C(Cc1ccccc1F)Oc1cccc(N2CCCC2=O)c1 +C#CCNC(=O)N1CCC(c2nc3cc(Cl)ccc3o2)CC1 +CCS(=O)(=O)N1CCN(S(=O)(=O)c2ccccc2OC)CC1 +CCNC(=O)c1ccc(C)c(NC(=O)CNC(=O)CC(C)(C)C)c1 +CC1CCN(C(=O)c2c[nH]c3ccccc3c2=O)CC1 +O=C(NCCN1CCOCC1)c1n[nH]c2ccccc12 +CCN(CC)S(=O)(=O)N1CCCc2ccc(N)cc21 +O=C(CCOc1ccc(Cl)cc1)Nc1cn[nH]c1 +O=C1CC(n2nnnc2-c2ccccc2Cl)C2COC1O2 +O=C1CC(c2ccccc2F)c2cc3c(cc2N1)OCO3 +CCCC1CN(C(=O)c2ccc(CNC(C)=O)cc2)CCO1 +Brc1ccc(-c2noc(-c3ccncc3)n2)cc1 +Cc1ccccc1-c1nc(-c2c(N)n(C)c(=O)n(C)c2=O)c(C)s1 +Cc1ccc(C(=O)N(C)C)cc1OC(=O)c1cnn(C)c1 +FC(F)(F)Oc1ccccc1CNCc1cscn1 +CCc1ccccc1NC(=O)CCC(C#N)c1ccncc1 +COc1cccc(CC(=O)Nc2ccccc2N2CCCC2)c1 +CC(C)Cn1c(N)c(C(=O)CN2CCOCC2)c(=O)[nH]c1=O +COc1cc(C)c(C(=O)N(C)CC(O)C2CC2)cc1OC +Cc1cc(CC(C)Nc2nc(-c3cccnc3)nc3c2cnn3C)[nH]n1 +CCn1nc(C)c(CNC(=O)Nc2cccc(C(F)(F)F)c2)c1C +CCOC(=O)c1csc(CNC(=O)c2c[nH]c3cccc(F)c23)n1 +CCN(C(=O)Nc1cnn(-c2ccccc2F)c1)C1CCCC1 +Cc1cc(-c2cccnc2)c(C#N)c(N2CCCC2)n1 +CCCc1cc(=O)[nH]c(SC(CC)C(N)=O)n1 +Cc1cccc(N(C)Cc2nnc(-c3cc(C)oc3C)o2)c1 +Cc1cccc(OCCCCSc2n[nH]c(N)n2)c1 +CCn1cc(C(=O)Oc2cccc3ccccc23)cn1 +N#Cc1sc2[nH]c(=O)c(-c3cccs3)cc2c1N +Cc1ccc(N)c2ccnc(C(=O)NCC(C)C)c12 +CCCc1ncc(CNC2(c3ccc(Cl)cc3)CC2)cn1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)NCCc1cccnc1 +CCn1c(SCCn2cccn2)nnc1-c1ccccc1 +Cc1nc(-c2c[nH]c(C(=O)N(C)Cc3ccco3)c2)cs1 +Cc1ccc(N2CC(C(=O)N(C)Cc3ccccc3)CC2=O)cc1 +COc1cccc(NC(=O)COC(=O)c2ccc(F)cc2F)c1 +COc1cccc(-c2ncc(C(=O)NC(C)(C)C)c(N)n2)c1 +CCc1onc(C)c1NC(=O)C1=C(C)OCCC1 +CCN(C(=O)c1cnn(-c2ccc(F)cc2)n1)c1ccc(F)cc1 +COC(=O)CCC(=O)c1cc(Oc2ccccc2)ccc1O +CC1=NCCc2c1n(-c1ccccc1)c1nccc(C)c21 +COc1ccccc1OCc1ccc(C(=O)OC(C)C)o1 +CN(C)C(=O)CNc1ccccc1OCC1CCCO1 +CC(=O)Nc1nc(C(=O)NC2CCc3c(O)cccc32)cs1 +COc1ccc(F)cc1NC(=O)N1CCN(CC(F)F)CC1 +N#Cc1cccc(NC(=O)COc2ccccc2NC(=O)C2CC2)c1 +COc1ncccc1CNC(=O)NCCc1ccccn1 +COc1ccccc1OCCN1CCNC(=O)C1 +CN1CC(C(=O)N2CCC(c3nnc4ccccn34)CC2)CC1=O +CC(C)CNC(=O)C1CCN(C(=O)Nc2ccccc2)CC1 +COC(=O)C1CCN(C(=O)Nc2ccc(F)cc2)CC1 +Cc1cc(C2CCCN2Cc2cn3ccccc3c2C#N)on1 +CN(CCO)C(=O)c1cccc(Br)c1N +O=C(Nc1cc(-n2cnnn2)ccc1F)NC1CCCC1 +O=C(NCC1=CCCCC1)C1CC(=O)N(C2CC2)C1 +CCCCN(CC)C(=O)NCc1ccc(OC)nc1 +Cc1nc2cc(F)cc(C(=O)N(C)Cc3ccsc3)c2nc1C +CC(CNC(=O)N1CCC1)CN(C)C(=O)OC(C)(C)C +O=C(c1cccnc1OCC(F)F)N1CCN(c2ncccn2)CC1 +O=C(Nc1ccccc1)c1c[nH]c(=O)n(-c2ccccc2)c1=O +CCOCCS(=O)(=O)c1ccc(C(=O)N2CCCC2)cn1 +O=C(Cc1ccc(NC(=O)c2cccc3ccnn23)cc1)NC1CC1 +CC(C)c1nnc(SCC(=O)N2CCOCC2)o1 +Cc1ncc(CN2CCC(Oc3c(C)cccc3C)CC2)s1 +Cc1cc(C(F)(F)F)nc2nn3cc(CCCO)cnc3c12 +COC(C)c1noc(-c2cc(C)nc3onc(C)c23)n1 +O=C(c1cc(COc2ccccc2)[nH]n1)N(Cc1ccncc1)C1CC1 +COC(=O)CCNC(=O)c1ccc(NC(=O)c2ccc(C)s2)cc1 +CNC(=O)CCNS(=O)(=O)c1ccc(Cl)cc1F +CCc1nc(C(C)NC(=O)Cc2c(F)cccc2F)cs1 +CCN(CC(F)(F)F)CC(C)(CO)c1ccccc1 +Cc1oncc1S(=O)(=O)N1CCCC(C)(c2ccccc2)C1 +CC(=O)N1CCc2cc(C(=O)NC(C)c3cnn(C)c3C)ccc21 +CCN(C(=O)Cn1nnc(-c2ccccc2)n1)c1ccccc1C +Cc1ccccc1-c1nnc(SCc2n[nH]c(=O)[nH]2)o1 +COc1ccc(CN2CCOC3(CCCC3)C2)cc1OC +Cc1cc(C(C)NC(=O)Nc2cnn(C)c2)c(C)s1 +Cc1cc(S(=O)(=O)NCc2cccs2)ccc1Br +COc1ccsc1C(=O)Nc1ccccc1-c1nc(C(C)C)n[nH]1 +Cc1cc(F)ccc1NC(=O)c1c(C)nn(-c2ccccc2)c1C +COCCNc1c(-c2ccc(OC)c(O)c2)nc2cnccn12 +O=C(c1cccc2c1OCCO2)N(CCO)C1CC1 +CNC(=O)COC(=O)c1ccccc1SCC=C(C)C +Cc1cc(C(=O)Nc2cc(Cl)c(N)c(Cl)c2)nn1C +CCSc1nnc(SC(C)C(=O)N2CCC(C)CC2)s1 +O=C(CSc1ccccc1)N1CCc2c([nH]c3ccnn3c2=O)C1 +O=C(c1sccc1C1CC1)N1CCN(Cc2ccncc2)CC1 +CCOc1cc(Cl)ccc1S(=O)(=O)n1cnc2ccccc21 +Brc1ccccc1-n1nccc1-c1cccnc1 +c1ccc(-n2ncc3c2ncn2c(-c4ccncc4)nnc32)cc1 +Cc1cc(C(=O)NCc2ccc(F)c(F)c2F)c(=O)[nH]c1C +CCN(CC)C(=O)Cc1csc(-c2ccccn2)n1 +COCCCC(=O)NCc1cc(Br)c2c(c1)OCCO2 +Cc1ccc(NC(=O)CNC(=O)c2cc(C)nn2C)cc1 +Cc1ccc(C(C)C)c(OCC(=O)N2CCCC2)c1 +OC(CN1CCOC2CCCCC21)c1cc(F)ccc1F +CC(=O)Nc1ccc(OCC(O)CSc2ccccc2)cc1 +CC1Cc2ccccc2N1C(=O)COC(=O)c1ccncc1F +COC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2ccc(C)s2)c1C +COc1ccc(NC(=O)N2CCN(Cc3ccncc3)CC2)cc1C +CNC(=O)Nc1cccc(COC2CCCC(C)C2)c1 +O=C(NCc1cscn1)c1occc1-c1ccccc1 +CC(=O)Nc1cccc(CNC(=O)c2cccc(-c3ccoc3)c2)c1 +Cn1c2ccccc2n2c(=O)c(=O)n(Cc3ccc(C#N)cc3)nc12 +Cc1noc(CSc2ncnc3sccc23)n1 +CCOCC1CCCN1C(=O)Cn1cccc(C(F)(F)F)c1=O +Cc1ccccc1C(C)(C)CNC(=O)c1ccnc(-n2cncn2)c1 +Cc1ccccc1OCCNC(=O)Nc1ccccn1 +NC(=O)CSc1nnc(Cc2cccs2)n1C1CC1 +COCc1ccccc1NCc1cc(=O)n2cc(Cl)ccc2n1 +CCCC1CCC(NC(=O)c2ccccc2OCC(N)=O)CC1 +O=C(C(O)c1ccc2c(c1)CCCC2)N1CCCC1 +C=CCN(Cc1ccccc1)C(=O)C1CCC(=O)N1 +CC(=O)c1cc(C(=O)NC2CC(=O)N(C3CCCCCC3)C2)cs1 +N#CCS(=O)(=O)NC1CCCc2ccccc21 +N#Cc1ccc(COc2cccc(-n3cnnn3)c2)c(F)c1 +Cc1c(CCCO)nnn1-c1nc(-c2ccccc2)cs1 +Cc1ccccc1OCCCC(=O)Nc1cccc(C#N)c1 +CCC(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2C)CC1 +Cn1cc(C(=O)Nc2nnc(C(C)(C)C)s2)c2ccccc2c1=O +OCCN1CCn2c(nc3cc(Cl)ccc32)C1 +O=C1CCSc2c1cccc2C(=O)NCCc1ccco1 +O=C(Cc1ccccc1)N1CCN(c2nc3ccccc3o2)CC1 +Cn1cnnc1SCc1nc2scc(-c3ccco3)c2c(=O)[nH]1 +N#CCCCOc1cccc(CN2CCOC(C(N)=O)C2)c1 +COc1ccc(-c2noc(-c3ccc(NCc4ccon4)nc3)n2)cc1 +COC(=O)c1cccc(COC(=O)c2ccoc2)c1 +CN1CCc2nc(NC(=O)COc3ccc(Cl)cc3)sc2C1 +Cc1cnn(C)c1C(=O)Nc1nnc(-c2ccc(F)cc2)o1 +Cc1ccncc1NC(=O)N1CCC(CC(C)C)C1 +Cn1c(=O)oc2cc(S(=O)(=O)N3CC(c4ccccn4)C3)ccc21 +CC(C)Cc1cc(C(=O)N2CCC3(CCCO3)CC2)on1 +Cc1cnn(CCC(=O)NC2CCN(c3ccccc3F)C2=O)c1 +C=CCn1c(SC(C(N)=O)c2ccc(F)cc2)nnc1C1CC1 +O=C(c1cccnc1)N1CCC(c2cnccn2)CC1 +Cc1nc(CNC(=O)c2sccc2OC(F)F)cs1 +CCOC(=O)c1nnsc1NC(=O)CCc1cccc(Cl)c1 +CC(C#N)N(C)S(=O)(=O)c1ccc2c(c1)OCCO2 +COC(=O)Nc1cccc(C(=O)Nc2ccc3ncccc3c2)c1 +CCNC(=O)N1CCC(COc2ccccc2)CC1 +CCC1CCCCC1NC(=O)CNC(=O)c1ccoc1C +Nc1cccc(-c2nnc(-c3ccc4c(c3)CCO4)o2)c1 +O=c1ccncn1Cc1nc(-c2cccc(F)c2)no1 +Cc1occc1-c1nnc(SCC(=O)NC2CCCCC2)n1N +Nc1c(Sc2ccc(Cl)cc2)nc[nH]c1=O +O=C(Cc1ccc(F)c(F)c1)Nc1ccc2c(c1)C(=O)CCC2 +COC(=O)c1cc(-c2ccc(N)cc2)nn1-c1ccc(Cl)cc1 +Cc1cccc(C(=O)NCC(=O)N(C)CC2CC2)c1 +CN(C)c1cccc(C(=O)Nc2nnc(C3CC3)s2)c1 +CCn1c(=O)c2cc(OC)c(OC)cc2n(Cc2ccccc2)c1=O +N#Cc1ccc(Oc2ccc(C(=O)NCC3CCCO3)cc2)cc1 +CCOc1cc(C(=O)N2CCC(OCC(C)C)CC2)ccc1OC +COCCNc1nc2c(c(=O)n(C)c(=O)n2C)n1CCOC +COc1cc(C#N)ccc1OS(=O)(=O)c1cccc2cccnc12 +Cc1cccc(NC2CCN(C(=O)Cc3c(C)noc3C)CC2)c1 +CN(C(=O)c1ccc(=O)n(C)n1)c1nc2ccccc2s1 +Cc1ccc(NC(=O)CSc2ccccn2)cc1S(N)(=O)=O +N#Cc1cn(CC(=O)NCc2ccc3c(c2)OCO3)c2ccccc12 +Cc1ccc(-c2cnn(CC(=O)Nc3cc(C)ccc3C)c(=O)n2)cc1 +O=C(CSc1nnc2ccccn12)Nc1cccc2[nH]cnc12 +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)NCc1ccc(F)cc1 +CC(=O)c1cccc(NC(=O)Cc2coc3cc4c(cc23)CCC4)c1 +O=C(OCc1nc2ccccc2c(=O)[nH]1)c1cccs1 +COc1ccc(C(=O)Nc2ccc(C(=O)NC(C)C)cc2)cc1 +Cc1ccc(C(=O)CCC(=O)Nc2cccc(F)c2)cc1 +Fc1cccc(NCc2cccc3cccnc23)c1 +Cc1ccc(C(=O)N2CC3COCC3(CNS(C)(=O)=O)C2)s1 +CC(NC(=O)NC1CCCCNC1=O)c1ccc2c(c1)OCCO2 +Cc1ccc(C)c(-c2ccc(N)c(=O)n2C2CC2)c1 +O=C(NCC1CC1)c1ccn(COc2ccc(F)cc2)n1 +COc1ccc(F)cc1C(=O)N1CCCC(CNS(C)(=O)=O)C1 +Cc1nc(C(NC(=O)Nc2cccc(F)c2F)c2ccccc2)n[nH]1 +O=C(CNC(=O)NCc1ccco1)NC1(c2ccc(Cl)cc2)CC1 +O=C(NC1(c2ccc(Cl)c(Cl)c2)CC1)c1csnn1 +O=C(Cn1nc(-c2ccccc2)c2ccccc21)NCc1cccnc1 +COc1ccc(N2CCN(CC(=O)NCCn3cccc3)C2=O)cc1 +O=C(NCC(=O)N1CCc2ccccc21)c1cc(Cl)ccn1 +COc1ccc(C(=O)CNC(=O)CC(C)C)cc1C +COc1ccc(NC(=O)c2cn(C)nc2C(C)(C)C)c(OC)c1 +c1ccc(C2=NNc3nc4ccccc4nc3C2)cc1 +Cc1noc(C)c1CCC(=O)Nc1ccc2c(C)c(C)c(=O)[nH]c2c1 +COc1ccc(CNC(=O)NCc2cc(C)on2)cc1NC(C)=O +Cc1c(N)cccc1NC(=O)COc1ccc(CC#N)cc1 +CN(C)C(=O)CNC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +C=CCNc1nc2c(c(=O)n(C)c(=O)n2C)n1C(C)C +CCC(C)NC(=O)C1CSc2ncc(C)c(=O)n2C1 +COc1ccc(CC2CCN(C(=O)Cn3cccnc3=O)CC2)cc1 +COc1nc2c(Br)c(F)cnc2cc1F +CCc1cnc(CN(C)C(=O)Nc2cc(C)cc3cccnc23)s1 +NC(=O)c1cccc(CSc2ncccc2Cl)c1 +CCc1nc2ccccc2n1CC(=O)N1CCCC(C(F)(F)F)C1 +CC(=O)c1ccc(NC(=O)CN2C(=O)COc3ccccc32)cc1 +CCOc1ccccc1NC(=O)Cn1c(C)cc(C)c(C(N)=O)c1=O +CN1C(=O)COc2cc(-c3noc(C(=O)NC4CC4)n3)ccc21 +Cc1cccc(NC(=O)CN(c2cccc(F)c2)S(C)(=O)=O)c1 +O=c1[nH]nc(-c2cnccn2)n1CCc1ccccc1 +O=C(Cn1cc(CO)nn1)Nc1cccc(Cl)c1 +COc1ccccc1CN(C(=O)CCn1cnc2ccccc21)C1CC1 +COC(=O)c1sc(NC(=O)C(C)Oc2ccc(C)cc2)nc1C +CC(C)CC(CCO)CNC(=O)NC1CCc2ccccc21 +CCOc1ccc(C(=O)NCC(=O)NCc2ccc(C#N)cc2)cc1 +COc1ccc(-c2nnc(SC(C)C#N)n2C(C)C)cc1 +N#CCCCNc1cc(Cl)c(Cl)cc1Cl +Cc1ccc(C(=O)N(C)C2(C#N)CCCC2)cc1C +CCC1CN(C(=O)c2cn(C)nc2-c2ccc(F)cc2F)CC(C)O1 +CCCn1nc(C)c(C(=O)Nc2cc(F)ccc2O)c1C +COc1ccccc1NC(=O)c1ccc(C)c(O)c1 +CCOc1ccc(NC(=O)C(CC)OCC)cc1Cl +COc1cc(CN(C)CCc2ccncc2)cc(N)c1O +O=C(NCc1ccc2c(c1)OCO2)C1COc2ccccc2O1 +CCCC(=O)Oc1ccc(C(=O)OC)cc1OC +O=C(Nc1ccc2c(c1)C(=O)NCCO2)c1ccc(F)c(F)c1 +Clc1ccc(-c2nn3c(-c4cnccn4)nnc3s2)cc1 +Cc1ccc(C(=O)Nc2nc(-c3ccc(N)cc3)cs2)cc1 +Cc1c(Cl)cccc1NC(=O)CSc1nccc(=O)[nH]1 +CC(C)CN1CC(C(=O)NC2CCC(c3ccccc3)CC2)CC1=O +CC1CCCCC1CNS(=O)(=O)c1ccc(N)nc1 +COC(=O)c1cc(-c2cc(Cl)c(O)c(Cl)c2O)nn1C +Cc1nn(Cc2ccccc2)c(C#N)c1Br +CC1CC1CNC(=O)NCCc1c[nH]c2ccccc12 +CC(C)CNC(=O)Cn1c(C(C)C)nc2c(N)cccc21 +CC(C)n1c(=O)c2ccccc2n(CC(=O)N2CCCCC2)c1=O +Cc1cccnc1CNC(=O)NC1CCCCC1C(F)(F)F +CCOc1ccc(C(=O)Nc2c(C)cccc2C)cc1OCC +Cc1cccc(-n2nnnc2SCC(=O)c2ccccc2)c1 +Cc1ccc(NC(=O)N2CCCC3CCCC32)cc1C(=O)N(C)C +CN(CC(=O)NCc1ccco1)c1nc2ccccc2s1 +Cn1nnnc1SCCCOc1ccccc1 +O=C(Nc1cccc(Cl)c1)N(Cc1ccncc1)CC1CCCO1 +CCCC(C)c1nnc(NC(=O)NCc2noc(C3CC3)n2)s1 +C=CCn1c(SCC)nc2sccc2c1=O +Cc1nc(-c2cccs2)sc1C(=O)N1CCCC1C(=O)N(C)C +Cc1ccc(OCCNS(=O)(=O)c2ccccc2)cc1 +Cc1ccc(S(=O)(=O)N2CCOCC2C2CC2)cc1N(C)C +COc1ccccc1NC(=O)COC(=O)CC1CCCCC1 +CCOC(=O)c1cccc(N(CC)S(=O)(=O)c2cccnc2)c1 +CCCNC(=O)c1ccc(NC(=O)c2csnn2)cc1Cl +Cn1nc(-c2ccccc2)cc1C(=O)NC1CNC(=O)C1 +O=C(Nc1ccccc1)c1sccc1S(=O)(=O)NC1CC1 +O=C(Nc1ccccn1)C1Cc2ccccc2CN1C(=O)c1ccco1 +CC(C)(C)CC(=O)N1CCN(CC(=O)c2ccco2)CC1 +Cc1nc(-c2ccncc2)[nH]c(=O)c1CCC(=O)N1CCC(C)CC1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)c1cn2cccnc2n1 +CN(C(=O)CSc1nc2ccccc2c(=O)n1C)c1ccccc1 +CC(C)CCOC1CCCCC1NC(=O)c1cscn1 +Cc1ccccc1OS(=O)(=O)c1cccc(S(C)(=O)=O)c1 +N#Cc1cccc(CS(=O)(=O)NC2CCCc3ccccc32)c1 +O=C(NCCc1cnn(-c2ccccc2)c1)C1CCCCC1 +Cc1ccc(C(=O)N2CCc3c(ncnc3N(C)C)C2)c2ccccc12 +Cc1ccc(C(C)NC(=O)NCC(C)N2CCOCC2)o1 +Cc1cc(NC(=O)c2ccccc2F)n(Cc2ccccc2)n1 +CC1(C(=O)NCCc2cccs2)Cc2ccccc2C(=O)O1 +COc1cc2c(cc1F)CCNC2c1ccc(=O)[nH]n1 +Cc1nn(C)c2ncc(C(=O)N(C3CCCC3)C3CC3)cc12 +Cc1ccccc1C(=O)NCCNc1ccc(-n2cccn2)nn1 +CCCn1c(-c2cccc(C)c2)nnc1S(=O)(=O)CC +Cc1cccn(CCCCC(=O)Nc2ccccc2N)c1=O +COc1ccc(S(=O)(=O)NCC2CCCO2)cc1Cl +CNC(=O)NCC(=O)N1CCCC1CC(=O)c1cccs1 +NC(=O)CN(C(=O)c1csc(-c2ncccn2)n1)C1CCCC1 +CCc1onc(C)c1NC(=O)N1CCC(N(C)c2ccccc2)CC1 +Cc1ccc(Cl)cc1NC(=O)Nc1cc(F)c2[nH]c(=O)ccc2c1 +O=C(NCC(O)c1ccc(F)cc1F)c1ccccc1F +Cc1cccc(C(=O)Nc2nnc(C3CC3)s2)c1C +CN(C)C(=O)c1ccc(NC(=O)Cc2ccc(OC(F)F)cc2)cc1 +Cc1csc(NC(=O)CC2CC3CCC2C3)n1 +CCN(CC)c1ncc(C(=O)NCc2ccncc2)c(N)n1 +CC(C)CC(=O)Nc1cc(C(=O)N2CCCCCC2)cn(C)c1=O +CCC1(C)OC(=O)N(CCc2c[nH]c3ccc(OC)cc23)C1(C)O +Cc1ccccc1C(=O)N(C)Cc1nc(-c2ccccc2C)no1 +O=C(Nc1ccc(OC2CCCC2)cc1)c1ccc(=O)[nH]c1 +COc1ccc(F)cc1NC(=O)CCOC(C)C +CCC(C)(NC(=O)C1CC1c1ccc(OC)cc1)C(=O)OC +CC(C)n1ncc2c1NC(=O)C(C#N)C21CCCCC1 +NC(=O)C1CCN(C(=O)c2cc(-c3ccco3)nc3ccccc23)CC1 +CC(C)CNS(=O)(=O)c1ccc(NC2CC2)nc1 +Cc1nc(N2CCCC(c3nnc4n3CCCCC4)C2)sc1C +CC(NC(=O)Cc1n[nH]c(=O)c2ccccc12)C(=O)NCCO +CNC(=O)NCC(=O)N1CCN(C(=O)c2ccccc2F)CC1 +CNC(=O)C(CC(C)C)NS(=O)(=O)c1c(C)nn(C)c1C +CC(C)(C)OC(=O)N1CCN(Cc2nnc(-c3ccco3)o2)CC1 +Oc1ccc(CNCCc2nc3ccccc3[nH]2)cc1Br +Cc1cc(NC(=O)CN2CCN(c3ccc(O)cc3)CC2)no1 +Cc1sc2ncnc(NCC(O)c3ccccc3)c2c1C +CCC(C(=O)NCC1(c2ccccc2)CCOCC1)n1cccn1 +O=C(NCCNC(=O)C1CC1)Nc1cc(Cl)ccc1Cl +Cc1sc2nc(CNC(=O)c3cc(C(C)C)on3)cn2c1C +CCCn1cc(-c2cc(-c3c[nH]cn3)c(C#N)c(N)n2)c(C)n1 +CCn1cc(C(=O)Nc2cccn(Cc3ccccc3)c2=O)cn1 +COc1ccc(-c2noc(C(=O)NCCC(C)C)c2N)cc1 +COC(=O)c1cnn(-c2ccc(C(F)(F)F)cn2)c1C +COc1ccc(C(=O)NCCSc2ccccc2)cc1 +O=S(=O)(NCc1cccs1)c1ccccc1OC(F)(F)F +CCC(=O)Nc1ccc2oc(C(F)(F)F)cc(=O)c2c1 +COCCN(CC(C)C)C(=O)Nc1cc(NC(C)=O)ccc1Cl +O=C(Nc1nc(-c2ccccn2)cs1)c1cc2c(F)cccc2[nH]1 +CC(C)C(CC(O)c1ccccc1)NS(=O)C(C)(C)C +CC(C)N1CCN(C(=O)c2cnc(-c3ccccc3)s2)CC1 +CCOc1ccc(F)c(C(=O)Nc2ccc(C#N)cn2)c1F +Cc1cccc(NCC(O)COc2ccc(F)cc2)c1 +Cc1noc(C2CCCN(C(=O)C34CC5CC(CC(C5)C3)C4)C2)n1 +O=C(NCCC(O)c1ccco1)NCc1cccs1 +COc1ccc(OCCNC(=O)Cc2cccs2)cc1 +COC(=O)c1cc2c(-c3ccccc3)nn(C)c2s1 +N#Cc1cc(-c2ccccc2O)cc2c1NCCC2 +Cc1nn2ccccc2c1C(=O)NCC(=O)N1CCc2ccccc21 +CNC(=O)c1ccc(C(=O)N(C)C)c(OC2CC2)c1 +CCCc1c(C(=O)NCc2nc3ccccc3[nH]2)[nH]c(C)c1C(C)=O +Cc1ccc(Br)cc1NC(=O)Nc1ccncc1 +CC1(C)CCCN1C(=O)c1ccc(Cl)c(Cl)c1 +O=C(CCCc1cccs1)Nc1nc(-c2ccccn2)n[nH]1 +CCc1cnccc1C(=O)N(c1ccc(C#N)cc1)C1CC1 +O=C(Cc1ccccc1)NCCC(=O)N1CCCC1c1cccs1 +O=C(NCCCC(=O)N1CCc2ccccc21)NCc1cccs1 +CCc1nn2cc(-c3cccc(Br)c3)nc2s1 +Cc1ccc2ncn(CC(=O)NCCc3ccc(F)cc3)c(=O)c2c1 +C=CCCCN(C)C(=O)CC1OCCc2ccccc21 +NC(=O)c1ccccc1COc1ccccc1Br +COCc1oc(-c2cc(C)ccc2OC)cc1C#N +CC(C)CN1CC23CN(C(=O)C(C)C)CC(CC2S1(=O)=O)O3 +Cc1nc(-c2nnn(Cc3ccccc3)c2C)no1 +CCCC1CN(C(=O)c2cc(C(CC)CC)no2)CCO1 +CCC(CC)N(CCO)C(=O)CN1CCCC1=O +Cc1cccc(C(CC(=O)Nc2nnc(C3CC3)s2)NC(N)=O)c1 +O=C(c1cc(Cl)cc(Cl)c1)N1CCC(O)(C(F)(F)F)CC1 +CN(CCC#N)C(=O)CNC(=O)c1cccs1 +CCNC(C#N)CCOc1cccc(S(C)(=O)=O)c1 +O=C(CSc1ccccc1Cl)c1ccco1 +Cc1ccc(Oc2ccccc2NC(=O)c2ccc(C)[nH]c2=O)cc1 +COc1cc(Cl)c(C)cc1NC(=O)CC(C)C#N +CCCCn1c(SCc2ccc(C(=O)N(C)C)cc2)n[nH]c1=O +CCOc1ccccc1CNS(=O)(=O)c1cccnc1 +CCN1CC(C(=O)NCCNc2cccc(F)c2C#N)CC1=O +Cc1c(C(=O)Nc2cc(C#N)ccc2OC(C)C)cnn1C +CN(C)c1nc2sc3c(c2c(=O)n1C)CC(C)(C)OC3 +CCC(C)NC(=O)Nc1ccc2c(c1)oc(=O)n2CC +CCOC(C)C(=O)N1CC(c2ccccc2C)CC1C +CCOCc1ccccc1CNS(=O)(=O)N1CCCC(C)C1 +CC1(C2CCN(C(=O)COC3CCCC3)CC2)OCCO1 +Cc1cnn(C2CCCN(C(=O)CCc3ccc(C4CC4C)o3)C2)c1 +COc1cc(Cl)ccc1C(=O)Nc1cc(C(N)=O)ccc1Cl +CC(=O)NC1CN(C(=O)c2ccoc2)CC1c1ccc(C)cc1 +CC(C)(C)Nc1ncnc(NCCc2cccs2)c1N +CCOC(=O)Cn1c(C)nc2cc3c(cc21)OCCO3 +CC(C)NC(=O)CN1CCCN(CC(=O)NC(C)C)c2ccccc21 +CCOc1ccc(CN2C(=O)C(C)(C)CS2(=O)=O)cc1 +O=C(NCCN1CCOCC1)Nc1ccccc1N1CCCCCC1 +CCC(C)(C)NC(=O)CSc1nc(N)c(C#N)cc1C#N +CCn1cc(NC(=O)c2cccc(OCC(F)F)n2)ccc1=O +CCN(Cc1ccccc1)c1ccc(N)c(OC)n1 +NC(=O)c1csc(C(=O)N2CCCC2CC(=O)c2ccccc2)c1 +Cn1c(COc2ccc(Cl)cc2Cl)cc(=O)n(C)c1=O +Cc1c(C(=O)NC2CCCC2)nnn1-c1ccccc1 +O=C(CCC1CCCO1)N1CCCc2cc(Cl)ccc21 +Cc1noc(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)n1 +COc1cc(NCc2c(C)nn(C)c2C)cc(OC)c1 +COC(=O)C1CCCN1Cc1nc(-c2ccc(F)c(OC)c2)oc1C +CNC(=O)NCc1ccc2c(c1)N(C(=O)c1ccc(OC)cc1)CC2 +CC(C)(C)C(NC(=O)CCNC(N)=O)c1cccs1 +CN(C(=O)C(O)C(O)C(O)C(O)CO)C1CCCCC1 +COC(=O)c1ccc(C(=O)NCc2cccc3c2OCCO3)nc1 +O=C(Nc1ccc(-n2ncc3ccccc32)cc1)N1CCCC(O)C1 +CN(C)c1c(Cl)cccc1NC(=O)NCCCC(N)=O +Cc1cc(NC(=O)c2cnn(-c3ccncc3)c2C)no1 +O=C(Cc1ccc(F)cc1F)Nc1ccc(N2CCCC2)nc1 +Cc1cc(C)cc(NC(=O)COc2cccc(N)c2)c1 +COCc1ccc(C(=O)Nc2cccc(C(=O)NC(C)(C)C)c2)cc1 +O=C(OC1CCOC1=O)c1cccc(S(=O)(=O)N2CCCC2)c1 +Cc1ccc(C)c(CC(=O)Nc2cccc(-n3cnnc3)c2)c1 +O=C1CCc2cc(C(=O)NCc3ccco3)ccc2N1 +O=C(Cc1cn2c(nc1=O)SCC2)Nc1ccc2[nH]ncc2c1 +COc1ccc(NC(=O)N2CCN(CC(=O)N3CCCC3)CC2)cn1 +Cc1cc(Cl)ccc1Nc1nc(=O)[nH]nc1C +O=C(Cn1c(=O)[nH]c(=O)c2ccccc21)NCC1CC1 +COc1ccccc1SCc1noc(-c2ccco2)n1 +N#Cc1sccc1-c1cccc(-c2cc[nH]n2)c1 +COc1ccc(N(C)C(=O)C2(O)CCCC2)cn1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3nc4ccccc4[nH]3)cc2)n1 +CC(=O)Nc1ccc(O)c(C(=O)N(C)Cc2ccccc2C)c1 +CC(=O)Nc1cccc(NC(=O)NC(C)c2ccc(F)c(F)c2)c1C +Cc1ccc2oc(C(=O)N3CCN(c4ccccc4)CC3)cc2n1 +Cc1cc(N)cn2c(-c3ccccc3Cl)nnc12 +O=C(OCc1nnc(-c2ccccc2)o1)c1cc(F)cc(F)c1 +CCOC(=O)C1CCCN(C(=O)Nc2ccc(F)cc2Cl)C1 +NC(=O)C1CCN(C(=O)c2cc(Cl)ccc2Cl)C1 +O=C(c1cccnc1)N1CCCC(c2n[nH]c3nccnc23)C1 +CCOc1cc(NCc2ccncc2)nc(C(C)C)n1 +CC(CO)CS(=O)(=O)NCCN1CCOCC1 +COc1cc(N)c(C(=O)N2CCC(O)C2)cc1OC +COc1ccc(C(=O)N(C)c2ccc3ccccc3c2)nn1 +CN1CC(C(=O)N(C)c2ccc(F)c(F)c2)CC1=O +COC(=O)c1sccc1NC(=O)c1ccc(C(F)(F)F)nc1C +CN(CCC1CCCCO1)C(=O)COc1ccc(Cl)cc1Cl +CS(=O)(=O)N1CCCc2cc(C(=O)NCc3ccco3)ccc21 +Cc1cc(NC(=O)COc2ccccc2)n(C(C)C)n1 +O=C(NCC1CCCO1)C1CCN(C(=O)c2cccc(F)c2)CC1 +Cc1cc(C(=O)N(CC2CCOC2)C2CC2)c(C)n1-c1cccnc1 +N#Cc1ccccc1Cn1c(C#N)nc2cccc(F)c21 +N#Cc1nnn(-c2ccccc2)c1C1CCCCC1 +CNC(=O)Cn1cc(NCC2CC3C=CC2C3)cn1 +CC(NC(=O)C(C)(C)C#N)c1ccc(S(C)(=O)=O)cc1 +CN(CCO)S(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +CCc1noc(CC)c1CNC(=O)Nc1ccc2nc(C)oc2c1 +O=S1(=O)N=C(N2CCc3ccccc32)c2ccccc21 +CCNc1cc(C(=O)N(CCC(F)(F)F)C2CCCC2)ccn1 +O=C(Nc1cncc(C#Cc2ccccc2)c1)N1CCOCC1 +COC(=O)N(C)CC(=O)Nc1ccc(F)c(F)c1 +COc1ccc(C(=O)N(C)C)cc1NCC(=O)Nc1cc(C)on1 +COc1ccccc1CC(=O)OCC(=O)Nc1ccccc1Cl +Cc1nnc2n(C)c(=O)c3c4c(sc3n12)CCCC4 +O=C(CC1OCCc2ccccc21)N1CCc2cc(F)ccc2C1 +COCc1nc2cc(-c3cccc4ccnn34)ccc2o1 +COc1ccc(F)cc1NC(=O)N1CCNC(=O)C1C(C)C +COc1ccccc1S(=O)(=O)CC(=O)N1CC(C)CC(C)C1 +CC1(C)CN(C(=O)C2CCN(c3cnccn3)CC2)CCO1 +Cc1cc(C)c(NC(=O)c2ccc(F)cc2)c(C)n1 +NC(=O)c1cnc2n1CCN(C(=O)COCC1CCCCO1)C2 +CCNC(=O)C1CCN(C(=O)c2c[nH]c3cccc(F)c23)CC1 +CN(C(=O)c1cnccn1)c1cccc2ncccc12 +O=S(=O)(NC1COc2ccccc2C1)c1ccccc1 +COC(=O)C(C)CNC(=O)Nc1cc(Cl)ccc1OC +Cc1ccc(CNc2cnn(CC(=O)N3CC(C)OC(C)C3)c2)s1 +COCCn1cc(NC(=O)Nc2cc(-c3nnco3)ccc2C)cn1 +Cc1ccc(C2(Cc3ccc(C)s3)NC(N)=NC2=O)o1 +COc1ccc(-c2cn3c(n2)sc2cc(N)ccc23)c(OC)c1 +CCC(=O)Oc1ccc(C(=O)Nc2cccc(OC)c2)cc1 +N#CCc1cccc(C(=O)Nc2cccc3cccnc23)c1 +O=C(NC1CCCc2ccccc21)c1cc(F)c(F)cc1Cl +COc1cccc(C(=O)NC(C)(CC(C)C)C(N)=O)c1F +CCCS(=O)(=O)N1CCCC1C(=O)c1ccc(C)cc1C +N#Cc1ccc(Cl)c(NC(=O)c2ccnc(F)c2)c1 +O=C1CCC(C(=O)NC2CCCOc3c2ccc(Cl)c3Cl)N1 +COCCCOc1ccccc1NC(=O)c1ccccn1 +CCC1CN(c2ncnc3[nH]ccc23)CCC1(C)O +COc1ccc(S(=O)(=O)N(C)C(C#N)CC(C)C)cc1C +Cc1cc(NC(=O)NC(C)(CO)C2CCCCC2)n(C)n1 +CCc1ccc2c(C3CN(c4ncc(C)cn4)C3)ncn2c1 +CCNC(=O)CCc1ccc(-c2ccccc2F)o1 +COCCOC(C)C(=O)N1CCCC1c1noc(C)n1 +Cc1cc(C(=O)OC(C)C(=O)Nc2ccc(F)c(Cl)c2)c(C)o1 +O=C(NC1CCCN(c2ccccc2F)C1=O)c1ccccc1 +CCS(=O)(=O)N1CCC(NC(=O)Nc2ccc(C)c(C)c2)CC1 +COCCNc1ncc(Br)c2ccc(N)cc12 +CC(C)c1nc(C2CCCN2C(=O)Cc2cnn(C)c2)no1 +Cc1cc(C)cc(NC(=O)CCn2c(=O)c(C)nc3ccccc32)c1 +O=C(Cc1ccc(F)cc1)Nc1ccc(NCC2CCCO2)c(F)c1 +Cc1cnn(C2CCCN(C(=O)CC3C(=O)Nc4ccccc43)C2)c1 +CCC(C)NC(=O)Cn1ncc2c1-c1ccccc1OC2 +CC1CCCC(C)N1C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +CCOc1cc(CNC(=O)COC)ccc1OC +OCC1CC(CN2CCOCC2)CN(Cc2ccncc2)C1 +C#CCOC(=O)CCC(=O)c1ccc2c(c1)CCCC2 +CC(=O)c1cc(F)cc(CSc2ncccn2)c1O +O=C(Nc1nc2c(s1)CCC2)C1CCOCC1 +COCC(O)CN(C)C(=O)CSc1ccccc1 +OCCc1nnc(COc2c(Cl)cccc2Cl)o1 +CNC(=O)c1cc(C)ccc1NC(=O)c1ccc(=O)n(C)c1 +COc1ccc(NC(=O)NCC(C)N2CCOCC2)cn1 +Cc1nc(C(C)C)ncc1C(=O)NC(C)c1nncn1C(C)C +Cc1noc(C)c1CN1CCN(C(=O)Cc2ccc(F)cc2)CC1 +CC=CCOC(=O)CC1c2ccccc2C=CN1C(C)=O +CCOc1ccc(-c2nnc(NC(=O)c3ccco3)o2)cc1 +CC(C)CC(=O)N1CCN2C(=O)c3ccccc3C2C1 +CC1CC(c2ccc3c(c2)OCO3)Cn2nc(N)nc21 +O=C(Nc1ccc(F)cc1)c1cc(-c2cccs2)on1 +CCCCN(C)c1ncnc(Nc2cccc(OC)c2)c1N +O=C(Nc1ccccc1)Nc1cccc(NC(=O)c2ccncc2)c1 +CCCCN(CC)C(=O)CSc1nc2ccccc2c(=O)n1C +CCCc1ncc(C(=O)NCCC2=CCCCC2)c(N)n1 +Cc1cccc(Cn2cc(NS(=O)(=O)c3cn(C)nc3C)cn2)c1 +CCC(Oc1ccccc1)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CCC1C(=O)NCCN1Cc1csc(-c2ccco2)n1 +CCN(C)c1nc(-c2ccc(Cl)cc2)c2c(N)n(C)nc2n1 +O=C(CCc1ccncc1)Nc1ccn(-c2ncccc2Cl)n1 +COc1cc(CNC(=O)N2CCCC(O)C2)ccn1 +COc1cccc(C(=O)NCc2nnc3n2CCCCC3)c1F +COc1cc(NC(=O)N(C)Cc2ccco2)ncn1 +COc1ccccc1OC(=O)CCn1c(=O)sc2ccccc21 +Cc1ccc(CNC(=O)CC2CSc3nc(C)c(C)c(=O)n32)cc1 +Cc1cc(C)n(-c2ccc(CNC(=O)C3CC3)c(C(F)(F)F)c2)n1 +CCOC(=O)c1sc(NC(=O)c2n[nH]c3ccccc23)nc1C +N#Cc1ccccc1OCC(=O)OCc1nc(-c2ccccc2)no1 +CC(C)(NC(=O)c1ccnc(OCc2ccccc2)c1)C(N)=O +O=C(Nc1ccc(C(=O)N2CCCC2)cc1)C1CC=CC1 +Cn1cccc1CN1CCN(C(=O)Cc2ccccc2)CC1 +Cc1ccc(S(=O)C(C)C(=O)Nc2cccc(C)c2C)nc1 +Cn1ccnc1SCc1cccc(C(=O)NCc2ccncc2)c1 +Cc1cc(C)nc(NCCCC(=O)NCc2nc3ccccc3[nH]2)n1 +CC(=O)NCCC1CCCCN1C(=O)c1ccn(C(C)(C)C)c1 +Cc1noc(COC(=O)c2ccc(C(=O)N(C)C)cc2)n1 +CC(Nc1cccc(C(=O)N2CCCC2)c1)c1cccnc1 +Cc1ccn(-c2ccc(NCc3ccc4c(c3)OCCCO4)nn2)n1 +CN(CCCOc1ccc(S(C)(=O)=O)cc1)c1nccnc1C#N +Cc1c(O)ccc(C(=O)COc2ccccc2F)c1O +Cc1cc(C)c(C(=O)Nc2ccc3c(c2)CC(=O)N3C)c(C)c1 +Cc1ccc(-n2nc(C)cc2NC(=O)C(C)c2cccc(F)c2)nn1 +O=C(NC1CCCC1)c1ccc(CN2CCCC2=O)cc1 +Cc1cc(Cl)c(C(=O)N(CCO)CCN2CCOCC2)cc1C +O=C(Cc1ccccc1F)OCC(=O)N1CCCC1 +COc1ccc(OC)c2sc(NC(=O)c3cc(C)nn3C)nc12 +CN(CCc1ccccn1)c1nccc(CCC(F)(F)F)n1 +CNc1nc(C)c(C(=O)NCC2COc3ccccc3C2)s1 +O=C(NCc1ccncc1)c1c[nH]c2ccc(F)cc2c1=O +CCOc1ccc2cc(C(=O)NCCC(=O)N(C)C)[nH]c2c1 +CN(CC1CCCCC1)C(=O)CCc1nnc(-c2ccsc2)o1 +Cc1sc2ncnc(N3CCC(C(=O)NC4CC4)CC3)c2c1C +C#CCNC(=O)CCCNC(=O)c1ccc(Cl)cc1 +COCC(C)OC(=O)c1nnn(-c2ccc(F)c(Cl)c2)c1C +Cn1cc(C(=O)NCCc2nc3ccccc3[nH]2)c2ccccc21 +Cc1nc(NC(=O)C2CCCO2)sc1-c1ccccn1 +CC(Cc1ccc(O)cc1)NC(=O)NCC1CCCO1 +Nc1cncc(S(=O)(=O)N(CCO)Cc2ccccc2)c1 +CC(=O)Nc1cc(Cl)ccc1NC(=O)Cc1ccc(F)c(F)c1 +CCc1cc(N)c2c(c1)C(=O)CC(c1ccccc1)O2 +O=C(c1c(F)cccc1Cl)N1CCN(Cc2cncs2)CC1 +O=C(Cn1cnc2ccc(Cl)cc2c1=O)N1CCCC1 +O=C(NCCc1ccccn1)c1ccc2noc(-c3ccccc3)c2c1 +Nc1cccc(NC(=O)c2cccc(Cn3ccc(=O)cc3)c2)c1 +COc1cc(C(=O)Nc2c(C#N)cnn2C)cc(OC)c1OC +CC(=O)Nc1c(Br)cc(C(N)=O)cc1Br +O=C(CSc1nc2c3ccccc3ncn2n1)NC1CC1 +O=C(CNC(=O)OCc1ccccc1)Nc1ccc(F)cc1 +CN(c1ccc(F)cc1)S(=O)(=O)N1CCCCC1 +O=C(NC1CC(=O)N(C2CC2)C1)c1cnc(Cc2ccccc2)s1 +COc1cccc(C(=O)N2CCN(C(=O)NC3CCCCC3)CC2)c1 +CCOC(=O)C(C)Sc1nnc2ccccn12 +CC(Nc1ccc2oc(=O)[nH]c2c1)c1ccc(F)cc1F +CC(=O)Nc1nc(C(=O)Nc2ccccc2N2CCCCC2)cs1 +CCn1cc(C(=O)NCc2cccnc2Oc2cccc(F)c2)cn1 +COCCOc1ncccc1NC(=O)N(C)Cc1ccncc1 +C=CCn1c(N)nnc1SCC(=O)NCC1CCCCC1 +CCn1cc(S(=O)(=O)Nc2cccc(F)c2)cn1 +COc1cc(CNc2ncccc2C(F)(F)F)cc(OC)c1OC +CN(Cc1ccccc1F)C(=O)CNc1cc(C#N)ccc1Cl +O=C(NCCCn1cnc2ccccc21)C1CC(=O)N(CC2CC2)C1 +COc1coc(Cn2c(=O)n(C)c(=O)n(C)c2=O)cc1=O +CCOCCC(=O)Nc1ccc(N2CCNC(=O)C2)nc1 +COc1ccnc(N2CCCC(Cn3cncn3)C2)n1 +CN(C)C(=O)c1c(OC2CC2)cncc1S(N)(=O)=O +COC(=O)C(NCc1ccc(C)c(F)c1)C(C)C +CCOCCNC(=O)NC(C)c1ccc(Cl)c(Cl)c1 +CCC(C)C(NC(N)=O)C(=O)NCCc1c(Cl)cccc1Cl +O=C(Cc1ccsc1)Nc1ccc(F)c(F)c1 +CCOc1ccc(C(=O)NCc2ccccc2C)cc1OCC +CN(CC1(c2ccccc2)CC1(C)C)c1nnc(C2CC2)o1 +COc1cc(OC)c(NC(=O)c2ccc3[nH]cnc3c2)cc1F +CC(C)(CNC(=O)c1cc(C2CCCCC2)n[nH]1)c1ccncc1 +N#CCC(=O)NCCOc1cccc(Oc2ccccc2)c1 +CCC(NC(=O)CCn1ccc(C)n1)c1ccccc1 +Cc1nc2ccc(NC(=O)NCc3cccnc3-n3cccn3)cc2o1 +O=C1NC2(Nc3ncccc31)C(=O)Nc1c2ccc(Cl)c1F +COC(=O)NC(C)(C)C(=O)NCC(C)Oc1ccccc1 +CCC(C(=O)N1CCC(NC(=O)c2ccco2)CC1)c1ccccc1 +CC(C)NC(=O)c1ccc(OCc2ccc(F)cc2)c(N)c1 +Cc1cc2c(c(C)c1N)N(C)S(=O)(=O)C2(C)C +CCC(OC)C(=O)Nc1cc(S(=O)(=O)CC)ccc1O +COc1ccc(COc2ccc(F)cc2N)cc1OC +Cc1cccc(NC(=O)COc2cccc3ccc(C)nc23)c1 +FC(F)(F)c1ccc(NCc2cccnc2-n2cncn2)nc1 +CCOC(=O)c1cc(-c2ccc(OC)c(N)c2)nn1C +Cc1ccc(CN(C)Cc2nnc(C)n2C)cc1F +O=C(c1ccccc1)N1CCN(Cc2cccc3ccccc23)CC1 +CC(=O)NC(c1ccccc1)c1ccc(Br)cc1 +Cc1ccc(C(C)(C)C)cc1C(=O)CCC(=O)N(C)C +CC(C)OC(=O)C(C)n1nc(C#N)cc1-c1ccncc1 +COCC(=O)Nc1ccc(NC(=O)c2ccc(C#N)cc2)cc1 +CC(=O)Nc1cccc(NC(C)C(=O)Nc2ccc(C#N)cc2)c1 +CCCc1ncc(C(=O)NCc2ccc(F)cc2)c(N)n1 +Cc1cc(NC(=O)c2occc2COc2cccc(C#N)c2)no1 +COC(=O)c1cccc(NC(=O)N(C)Cc2ccc(OC)c(O)c2)c1 +CCOc1ccc(C(O)CNc2ccccc2C)cc1 +CC(C)(C)OC(=O)N1CCNC(c2cc(F)ccc2F)C1 +CC(C)NC(=O)CCNc1ccc(F)c(F)c1F +c1ccc2sc(-c3ccc(-n4cnnc4)cc3)nc2c1 +Cc1ccc(-c2ncco2)cc1NC(=O)C(C)c1c(C)noc1C +Cn1c(=O)oc2ccc(NC(=O)Cc3ccc[nH]3)cc21 +Cc1nc(C)c(CCC(=O)N(C)c2ccc(F)c(F)c2)c(=O)[nH]1 +CCn1c(=O)n(CC(=O)Nc2ccc(OC)cc2)c2ccccc21 +CCOc1ccccc1NC(=O)C1CC2CCC1O2 +CN(C)S(=O)(=O)N(CC(F)(F)F)C1CCOCC1 +CCn1nc(C)c(C(C)NC(=O)c2ccnn2C(F)F)c1C +Cc1nnc(NC(=O)Cc2coc3ccc(Cl)cc23)s1 +Cc1ccc(C)c(NC(=O)CSc2ccc(N)nc2)c1 +CC(C)N(C(=O)Cn1nnnc1CCc1ccccc1)C(C)C +COc1cccc(OCC(=O)Nc2cccnc2)c1 +CC(NC(=O)CNC(=O)c1ccoc1)c1ccncc1 +CC(=O)Nc1ccc(NC(=O)NCc2cccc(OC(C)C)c2)cc1 +COc1c(F)cc(NC(=O)NCC(=O)Nc2ccccc2)cc1F +CC1(C(=O)Nc2cnc3ccccc3c2)Cc2ccccc2C(=O)O1 +Cc1ccc(CC(=O)Nc2cccc(C(=O)Nc3ccccn3)c2)cn1 +COc1ccc(S(=O)(=O)Nc2ccccn2)cc1 +Cc1nn(C(C)(C)C)c(C)c1C(=O)N1CC(C)C(N2CCOCC2)C1 +N#Cc1ccc(C(NCC2CN3CCCCC3CO2)C(N)=O)cc1 +NC(=O)C1CCN(C(=O)Nc2nc3ccccc3s2)CC1 +Cc1cscc1-c1cnc(-n2cnnc2)c(C)c1 +N#Cc1c(F)cccc1NCCNC(=O)CC1CCCCC1 +CCCn1ncc(-c2ccc(OC)c(C)c2)c(N)c1=O +CC1(NC(=O)c2cccc(C3OCCO3)c2)Cc2ccccc2C1 +CCCc1ccc(C(N)C(=O)NCCCO)cc1 +Cn1nccc1C(=O)NC(c1ccccc1OC(F)F)C(F)(F)F +CCCNC(=O)Nc1ccc(NC(=O)C(C)C)cc1 +Cc1nc(CNC(C)c2nnc3ccccn23)oc1C +CCCN1C(=O)C(NC(C)=O)(C(F)(F)F)N=C1c1ccccc1 +CSc1ccc(CNC(=O)c2nonc2N)cc1 +O=C(NCc1cscn1)c1cnn(Cc2ccccc2Cl)c1 +COCC(=O)Nc1nnc(C2CC(=O)N(c3cccc(C)c3)C2)s1 +O=C1CCCc2cc(NC(=O)NCCc3ccccn3)ccc2N1 +CC(=O)c1cc(F)ccc1OS(=O)(=O)c1cc(F)ccc1F +COC(=O)CCCN1C(=O)COc2ccc(N)nc21 +Cc1ccc(NC(=O)CN2C(=O)CCn3nc(C)cc32)c(Cl)c1 +O=C(Cn1ccc(=O)c2cc(Cl)ccc21)Nc1ncccn1 +CCc1nncn1CCNC(=O)c1cn(C)nc1C(C)(C)C +C=C(C)CN(CC)C(=O)COc1ccccc1F +Cn1ccc(NC(=O)c2cc3c(s2)-c2ccccc2OC3)n1 +CCc1nccn1S(=O)(=O)c1cc(C)c(OC)cc1C +COc1cc(OC)c(NS(=O)(=O)c2ccc(C)cc2F)cc1F +C#CCOC(=O)CCC(=O)Nc1ccc(C(C)=O)cc1 +COc1ccccc1Oc1ncnc2sccc12 +CCc1noc(CC)c1CNC(=O)NCc1ccc(C#N)cc1F +O=C(NC1CCC(O)CC1)N1CCCC1c1nc2ccccc2s1 +O=C(c1cccc(C(F)(F)F)c1)c1cnccn1 +O=C(CCn1ccc2ccccc21)Nc1ccccc1O +C=CCSc1nnc(NC(=O)c2oc3ccc(F)cc3c2C)s1 +COC1CCN(C(=O)c2cnoc2C)C1Cc1ccccc1 +CCOC(=O)C1CCN(C(=O)CN2C(C)COCC2C)CC1 +COC(=O)C1CN(C(=O)c2ccc(C)cc2)c2ccccc2O1 +O=C(Nc1ccc(Cl)cc1)N1CCN(c2cccc(O)c2)CC1 +COc1ccccc1C(=O)Nc1ccc(C(=O)N2CCCC2)cc1 +O=C(c1cc(Br)c[nH]1)N1CCc2sccc2C1 +CCOC(=O)c1cn(Cc2ccc(OC)cc2)c2ccccc2c1=O +O=C(Nc1cccc(F)c1)c1sccc1C1CC1 +CC(C)n1nccc1NC(=O)N(C)CC(=O)Nc1ccccc1 +COCc1ccc(CN2CCOC(CC(=O)OC)C2)o1 +Cc1ccc(C2Nc3ccccc3C(=O)N2C2CC2)cc1F +Oc1ccc2c(c1)nc(C(F)(F)F)n2-c1ccncc1 +O=C(NCCC1=CCCCC1)C1CCCN1C(=O)C1CC1 +CC(C)CCOC(=O)c1cnc(C2CCCO2)s1 +CCC(C)C(=O)N1CCSc2ccc(N)cc21 +CN(CCc1ccc(F)cc1)C(=O)CNC(=O)C1CC1 +Cc1cc(NC(=O)c2nnc3ccccc3n2)no1 +O=C(Nc1cccnc1)c1cnc(C2CCCO2)s1 +O=C(c1cccnc1)N1CCN(C(=O)c2ccoc2)CC1 +Cn1ncc2c(NCCNc3cccc4ccccc34)ncnc21 +CCc1onc(C)c1NC(=O)NCc1nccn1Cc1ccccc1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)N2CC(C)OC(C)C2)c1 +Cc1cccc(C(C)(C)CNC(=O)c2cnn(-c3ccncc3)c2C)c1 +Cc1cccc(CS(=O)(=O)N2CCN(c3ccccc3F)CC2)c1 +CC(=O)N1CCCCC1CNC(=O)OC(C)(C)C +CCOc1c(C)cc(COC(=O)c2c(C)nn3cccnc23)cc1C +Cn1ccc(C(=O)Nc2ccc(Cn3cccn3)cc2)n1 +Cn1ccnc(NC(=O)Cn2ncc3ccccc32)c1=O +COC(=O)CNc1ccccc1C(=O)N1CC(C)CC(C)C1 +O=C(Nc1cc(Cl)ccc1O)c1c(O)cc(F)cc1F +CCCC(C)CC(=O)NC1CCN(C(=O)c2ccccc2)CC1 +CSc1sc(NC(=O)c2ccc3[nH]cnc3c2)nc1C +Cc1cc(CN(C)S(=O)(=O)c2ccc3c(c2)CCO3)no1 +CCC(C)OC(=O)C(C)N1CCCOc2ccc(N)cc21 +O=C(OC(c1ccccc1)c1ccccn1)C1CCCO1 +Cn1nc(CNS(=O)(=O)c2ccc3c(c2)CCCC3)cc1C1CC1 +COc1ccc(F)cc1NC(=O)C1CC(=O)N(C2CCC(C)CC2)C1 +OC(Cc1cccc(Cl)c1)c1ccc2c(c1)OCO2 +CN(Cc1cc(N)ccc1Cl)S(=O)(=O)c1cn[nH]c1 +O=C(CCCCO)NCC1c2ccccc2Sc2ccccc21 +CC(C)C(=O)Nc1ccc(C(=O)N(C)CC2CC2)cc1 +Cc1ccc(NC(=O)C2COc3ccccc3O2)c(Cl)c1 +Cc1ccc(NC(=O)c2cn(-c3cc(N4CCCC4)ncn3)cn2)cc1 +Cc1ccc(NS(=O)(=O)c2ccc(F)c(F)c2)cc1F +CC1CCCCC1NC(=O)N1CCN(C(=O)c2ccoc2)CC1 +CC(C)(CO)NC(=O)c1nc(-c2ccc3[nH]ccc3c2)no1 +Cc1nn(CO)c(C)c1Sc1ccc(Cl)cc1 +O=C(NCc1ncc2c(n1)CCC2)c1cccc(Cn2cccn2)c1 +CCOc1cc(C(=O)Nc2cccc3cccnc23)ccc1OC +O=C(c1cc(-c2ccccc2)on1)N1CCCN(c2cccnn2)CC1 +CN1CCc2nc(NC(=O)CSc3ccc(F)cc3)sc2C1 +Cn1c(=O)c2ccn(CC(=O)Nc3ccccc3F)c2n(C)c1=O +CC1CCN(c2ccc(=O)n(CC(=O)NCc3ccncc3)n2)CC1 +Cn1c(=NC(=O)CNC(=O)c2ccco2)[nH]c2cc(Cl)ccc21 +COc1ccc(NC(=O)CSc2nnc(C(C)(C)C)n2N)cc1 +C#CCN1CCN(C(=O)NCc2nnc3n2CCCC3)CC1 +Cc1noc(CCC(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)n1 +Cc1[nH]ccc1C(=O)N1CCCC(C)(Cc2ccc3c(c2)OCO3)C1 +CC(C)COC1CCN(C(=O)Cc2cn(C)c3ccccc23)CC1 +C=CCNC(=O)NCc1ccc(OC)c(OC)c1 +O=C(CSc1ccccc1)Nc1ccc2c(c1)OCO2 +COC(=O)c1cc(Cn2ccccc2=O)c(C)s1 +CC(C)(C)CN1CC(F)C(OCc2nc3ccc(C#N)cc3[nH]2)C1 +O=c1c2sccc2ncn1Cc1ccc2nonc2c1 +CC(C)(C)n1cc(CNCc2ccc(-n3cccn3)nc2)cn1 +CN(CCc1ccccn1)Cc1ccccc1C(F)(F)F +CC(NCC(F)(F)F)(C(N)=O)c1cccc(O)c1 +COc1ccccc1-c1n[nH]c(C(N)c2ccccc2)n1 +CCn1cc(C(=O)N(Cc2c(F)cccc2Cl)C2CC2)cn1 +CCOc1cccc(NC(=O)C2CC2(Cl)Cl)c1 +O=C(NCCN1CCOCC1)Nc1cc(-n2cccc2)ccc1F +CCCCOc1cccc(NC(=O)c2cccc(S(C)(=O)=O)c2)c1 +CCCNc1c(F)cc(C(=O)NC(C)CC)cc1F +CC(=O)c1cccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)c1 +COCCNC(=O)C1(C)CCC(=O)N1c1ccc(C)cc1C +CCn1nc(C)cc1C(=O)N1CCCC1c1cccn1C +Cc1ccccc1NC(=O)C(C)Sc1nncn1C +CC(C)N1CCN(C(=O)Cc2cccc(O)c2)CC1 +CC(CC(=O)N1CCC(n2ccnn2)CC1)c1ccc(F)cc1F +O=C(OC1CCOC1=O)c1sc2cc(F)ccc2c1Cl +Cc1n[nH]c(SCC(=O)c2c[nH]c3ccccc23)n1 +C=CCNC(=O)Cc1csc(NC(=O)OC)n1 +O=C(NCCNc1ccc(-n2cccc2)nn1)Nc1ccccc1 +COc1ccc(S(=O)(=O)Nc2ccc(Cl)cn2)c(N)c1 +COc1ccc2c(=O)n(Cc3nc(C)no3)ccc2c1OC +CCC(CC)CN(CC)C(=O)NC(C)c1nncn1C +COc1cc(C(=O)N2CCc3cc(F)ccc3C2)ccc1OC(C)C +CC1(CCNC(=O)NC(c2ccccc2)c2ccco2)OCCO1 +CCCc1ncc(C(=O)N2CCN(CC)CC2)c(N)n1 +O=C(Cc1ccc(Cl)cc1)NCc1cc2ccccn2n1 +Cc1ccc(C(=O)CSc2nc(C)ccc2C#N)c(C)c1 +Cn1c(C(F)(F)F)nn(CCNC(=O)C2CCCCC2)c1=O +Cc1c(Cl)cccc1NC(=O)c1ccc(C(N)=O)cc1 +COCCCC(=O)Nc1cccnc1N1CCCCC1 +O=C(NCc1nnc2n1CCCC2)c1cccc(OCC(F)F)n1 +COC(=O)CN1CCc2ccc(C(C)(C)C)cc2C1 +COCCC1(CNC(=O)NC(C)c2nccs2)CCCC1 +O=C(Nc1ccc2c(c1)OCCO2)C1CCCc2c1[nH]c1ccccc21 +COC(=O)C(C)Cc1ccc(NC(=O)c2cscn2)cc1 +CCn1nccc1C(=O)Nc1c2c(nn1-c1ccccc1)CCC2 +COc1ccc(Cc2cc3c(cc2OCC(N)=O)OCO3)cc1 +COCCCNC(=O)CN(C)C(=O)c1cc(Cl)ccc1O +CC(=O)c1cccc(NC(=O)CCC(O)c2cccs2)c1 +CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccs2)C1 +CC(C)Cc1noc(-c2ccc(S(N)(=O)=O)cc2)n1 +N#Cc1ccc(CCC(=O)OCC2CCCCO2)cc1 +COc1cccc(CNC(=O)c2ccc(NC(N)=O)cc2)c1 +CC(=O)Nc1ccc(SCC(O)COc2ccccc2C)cc1 +COC(=O)C(C)n1ccnc1Cc1ccccc1OC +CCN(Cc1ccoc1)C(=O)Nc1ccn(-c2ccccc2)n1 +O=S(=O)(c1ccc(Cl)cc1)N1CCCC1c1cccnc1 +CCOc1cc(CO)ccc1OCc1ccccc1C +CCc1nc(CN2CCN(C(=O)C3(C#N)CCCC3)CC2)cs1 +O=c1cc(C2CCC2)ncn1Cc1ccc(F)c(Br)c1 +N#CCOc1cccc(CNC(=O)c2ccc(F)nc2)c1 +CC(=O)Nc1ccc(NC(=O)CCSc2ccccc2Cl)cc1 +COCCNC(=O)Nc1ccccc1-n1cccn1 +Cc1cc(C(C)NC(=O)c2cc(C)sc2C)c(C)o1 +CC(=O)Nc1cccc(NC(=O)N(CCO)Cc2ccccc2)c1C +CC(=O)NC(CC(=O)N(C)CC(=O)NC(C)(C)C)c1ccc(C)cc1 +N#Cc1cccnc1NCCOC(=O)c1ccc(-n2ccnn2)cc1 +Cc1ccnc(NC(=O)c2ccc(Cl)cc2N)c1 +CCc1nc(C)c(C(C)OC(=O)c2cn(C)nc2C)s1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)Nc1ccc(F)cc1 +COc1cc(C#N)ccc1OCCCC(=O)Nc1sccc1C#N +C1=C(c2ccccc2)Nc2nnnn2N=C1c1ccccc1 +COc1cccc2c1OCC(CN1CCOCC1)C2N +CCc1nnsc1C(=O)NC(Cn1cncn1)c1ccccc1 +CCOC(=O)c1c(C)[nH]c(C(=O)N(C)CC(=O)NC(C)(C)C)c1C +COc1ccc(OC)c(-n2nnc(C#N)c2-c2ccccc2)c1 +Cc1ccc(C(O)CCC(=O)NCC2CCCO2)cc1N +Cc1ccc(C#N)c(NCCNS(C)(=O)=O)n1 +C=CCNC(=O)Cn1c(CCNC(C)=O)nc2ccccc21 +Nc1cccc(NC(=O)COc2ccc(F)cc2Br)c1 +CCc1nc(C)sc1CNC(=O)c1c(O)cccc1O +Cc1ccc(NC(=O)c2cc(-c3cccnc3)[nH]n2)cc1N(C)C +Cc1cc(C)c(NC(=O)CSc2nnc(-c3ccco3)o2)c(C)c1 +CCc1oc(C(=O)N2CCC(OCc3ccccc3C)CC2)cc1C +CC(C)CC(=O)Nc1nc(C(=O)N2CCCCCC2)cs1 +CC(C)S(=O)(=O)Nc1ccc(CC(=O)NC2CC2)cc1 +CCn1nc(C)cc1C(=O)Nc1nc(-c2cccs2)cs1 +Nc1ccc(C(=O)Nc2ccc(C(F)(F)F)cc2)c(Cl)c1 +COc1cc(Cl)ccc1-c1nc(-c2ccn3cnnc3c2)no1 +CN(Cc1cccc(O)c1)C(=O)c1ccc(N)cc1 +CSc1cccc(NC(=O)Nc2cc(C)on2)c1 +CC1CN(C(=O)c2n[nH]c3ccccc23)c2ccccc21 +COC(=O)C(C)(C)NC(=O)C(C)n1nc(C)cc1C +N#Cc1ccc(C(=O)NCC(=O)Nc2cccnc2)cc1 +CC(=O)c1sc(NC(=O)COc2ccc(C)c(C)c2)nc1C +COC(=O)c1ccc(C(=O)Nc2ncc(C)s2)nc1 +O=C(c1cnn(-c2ccccc2)n1)N1CCCC1Cc1ccccc1 +COc1ccccc1C(C#N)N(C)C(=O)c1ccco1 +Cc1nc(C)c(C(=O)Nc2cc(-c3cccnc3)n[nH]2)o1 +Cc1ccc(C)c(OCc2ccc(C(=O)NCCCO)o2)c1 +COC=C1N=C2c3ccccc3CC3(CCCCC3)C2C(=O)N1 +CCc1ncc(C(=O)Nc2ccc(Cl)c(C(N)=O)c2)s1 +O=C(NCc1ccco1)C1CCCN(S(=O)(=O)c2ccccc2)C1 +CCCNC(=O)NC1CCN(c2nc(C)cc(C)n2)CC1 +CN(C)C(=O)N1CCC2(CCC(=O)N(CC3CCCO3)C2)CC1 +COC(=O)c1cccc(CCNC(=O)NCc2ccc(O)cc2)c1 +CCCOc1ccc(-c2ccc(C(N)=O)c(N)n2)cc1 +Cc1nc2cc(C(=O)NCc3cscn3)ccc2n1-c1ccccc1 +CN(C)C(=O)c1cc(NCCC2CCCC2)ccn1 +Cc1ccc(C(=O)C2CCN(S(C)(=O)=O)CC2)c(C)c1 +O=c1[nH]ncc(NCC(O)c2ccccc2C(F)(F)F)c1Cl +Cc1c(C(=O)N(C)CCOc2ccccc2F)oc2c1C(=O)CCC2 +Cn1cc(CNCCc2c(F)cccc2F)c(-c2ccncc2)n1 +CC(=O)NCCC(=O)Nc1cc(C(F)(F)F)ccc1Cl +Cn1c(SCC(=O)c2ccc3ccccc3c2)nnc1C1CC1 +CCc1nc2ccccc2n1CC(=O)Nc1ccncc1 +O=C(COC1CCCC1)Nc1nc(-c2ccc3c(c2)OCO3)cs1 +O=C(c1ccc[nH]1)N1CCN(Cc2ccc3c(c2)CCO3)CC1 +CCCCOc1ccc(C(=O)NCc2nc(C)no2)cc1 +COc1cc(N)ccc1S(=O)(=O)NCCS(N)(=O)=O +Cc1nc(C)c(C(=O)OCc2cn3cc(Cl)ccc3n2)s1 +COC(=O)c1cc(-c2ccc(C)c(C)c2)[nH]c(=O)n1 +CC(CO)NC(=O)Nc1ccc(Oc2ccc(F)cc2)nc1 +CCCn1nnnc1CSc1cc(C#N)ccn1 +CCc1nnsc1C(=O)NC1CC(C(=O)OC)N(C)C1 +CSc1ccc(C(=O)CCC(=O)N2c3ccccc3CC2C)cc1 +CCOc1ccc(-c2cnc(N(C)C)c(C#N)c2)cc1 +CC(C)N1CC(C(=O)Nc2cccnc2N2CCOCC2)CC1=O +CC(=O)N1CCN(CC(=O)NC(C)c2ccc(F)cc2)CC1 +CC(C)OCC(O)CN1CCN(c2cccc(C(F)(F)F)c2)CC1 +O=C(Nc1ccccc1F)c1cnc2n(c1=O)CCS2 +COc1cc(CCC(=O)Nc2ncc(C)s2)cc(OC)c1OC +COc1ccc(C2=CCN(C(=O)c3csnc3C)CC2)cc1OC +O=C(NC1CCCCC1)c1ccc(COCC(F)(F)F)o1 +N#Cc1cc(-c2ccccc2)n(Cc2ccccc2C#N)n1 +CCC(OC)C(=O)NC(C)c1ccc(S(N)(=O)=O)cc1 +NC(=O)c1ccc(CNC(=O)N2CCN(c3ncccn3)CC2)cc1 +O=C(OCc1cc(-c2ccccc2)on1)c1cc(-c2ccco2)n[nH]1 +COC(=O)c1ccc2c(c1)nc(-c1cc[nH]n1)n2C +CS(=O)(=O)Nc1ccccc1-c1nc(-c2ccncc2)no1 +Cc1csc(=O)n1CC(=O)Oc1cccc(F)c1 +CCc1cc(=O)[nH]c(-c2cccc(NC(=O)c3c[nH]c(=O)[nH]3)c2)n1 +CNC(=O)CCC(C)(C)NC(=O)c1oc2cc(OC)ccc2c1C +CC(C)N(C(=O)COc1ccccc1Br)c1cccnc1 +CC(C)(C)Nc1ncnc(Nc2nccs2)c1N +Cc1ncc(-c2nc3cnn(Cc4ccccc4)c3[nH]2)n1C +CC1Oc2ccccc2OC1C(=O)NC1CCCC(O)C1 +CC(=O)NCCCN(C)C(=O)NCc1ccc(C)cc1N(C)C +COCc1c(C(=O)NCCCn2nc(C)cc2C)oc2ccccc12 +O=C(CC1CCCO1)N1CCCC1Cn1cccn1 +CCNC(=O)c1ccc(CNC(=O)Nc2ccc(C)c(F)c2)cc1 +CCN(CC(=O)NC(C)C)S(=O)(=O)N1CC(C)CC(C)C1 +Cc1noc2nc(C(C)C)cc(C(=O)NCCCOC(C)C)c12 +Cc1nc2c(cnn2-c2ccc(F)cc2)c(=O)n1C1CCCC1 +CCCCc1nc(CSc2nnnn2-c2ccccc2)no1 +COc1ccc(C(C)NC(=O)c2cn3cc(Cl)ccc3n2)cc1 +O=c1c2cnn(-c3ccccc3)c2nnn1Cc1cccnc1 +CCNC(=O)C(C)NC(=O)C1CC(=O)N(c2ccc(SC)cc2)C1 +COc1ccc(CN2CCN(CC(F)F)CC2)c2ccccc12 +CCc1nc(CC(=O)NCC2CCCO2)cs1 +Cc1n[nH]cc1NC(=O)Cc1c[nH]c2ccccc12 +CCCCn1nnnc1Cn1cnc2c(cnn2C)c1=O +CC(NC(=O)NCCc1nccn1C(F)F)c1nccs1 +Cc1nn2ccccc2c1C(=O)NCC(=O)N1CCCCC1 +COc1ccccc1OCC(=O)Nc1nc(C)c(C)s1 +Cc1cc(C)c(NC(=O)N2CC(Oc3ccccc3F)C2)c(C)n1 +COc1cccc(OCC(=O)N2CC(C)OC(C)C2)c1 +C=CCn1c(C)nnc1SC(C)C(=O)Nc1cccc(C#N)c1 +O=C(Cn1cc(Br)ccc1=O)Nc1ccc(Cl)cc1 +Cc1ccnc2nc(C(=O)N3CCSc4ccc(Cl)cc43)nn12 +Cc1cnc(N2CCCC3(CC(Oc4ncccn4)CO3)C2)nc1 +Cc1noc(CN(C)Cc2nc(-c3cccc(Cl)c3)oc2C)n1 +O=C(Nc1cc(-c2cccs2)no1)c1ccccn1 +CC(=O)Nc1ccc(NC(=O)c2ccc(F)cc2F)cc1 +Cc1ccc2[nH]c(C(=O)N(Cc3ccco3)C3CC3)cc2c1 +Cc1noc(C)c1CC(=O)NC(c1ccc(F)cc1)C1CCCO1 +O=C(c1cnc2cc(N3CCNC3=O)ccc2c1)c1ccccc1O +CCOC(=O)C1(C)Oc2ccccc2N(Cc2ccccc2F)C1=O +CCN(CCCCO)C(=O)c1cccc2nccnc12 +O=C(Nc1ccc2c(c1)OCCO2)C1CC2CCC1C2 +C#CC(CC)(CC)NS(=O)(=O)c1cccc2nonc12 +COC(=O)C(C)S(=O)(=O)Nc1ccc(F)cc1N +CC(=O)N(C)CC(=O)OC(C)c1nc2ccccc2s1 +COc1ccc(-n2ccc(CNC(=O)C3CC3)n2)cc1 +Cc1ccc(C(=O)NCCC2CNc3ccccc32)c(C)c1 +COc1cc(CNc2ccc(C#N)c(Cl)c2)ccn1 +CN(Cc1cnn(C)c1)S(=O)(=O)c1cccc(Br)c1 +Cc1nc(CN(C)C(=O)Nc2cc(C)n(-c3cccc(F)c3)n2)no1 +Cn1c(=O)c(C(=O)N2CCC(C)(O)C(C)(C)C2)nc2ccccc21 +O=C(C1CCC1)N1CCC(N2CCNC2=O)CC1 +Cc1ccc(C)c(S(=O)(=O)N(C)CC(=O)Nc2ccon2)c1 +COC(=O)COc1cccc(NC(=O)c2ccncc2)c1 +COc1ccc(C(=O)NCc2ccccc2Cn2cccn2)cn1 +COc1cccc(OCCC(=O)N(C)CCO)c1 +C=C(C)COc1ccc(-c2cn(-c3cccc(N)c3)nn2)cc1 +CCC(C)NC(=O)c1cn2c3c(cc(Br)cc3c1=O)CC2 +Cn1ccc(C(=O)NC2CCC(c3ccccc3)CC2)cc1=O +O=C(NCCC(=O)N1CCCc2ccccc21)c1cnc2[nH]ccc2c1 +CCOc1cccc(NC(=O)N2CCN(C(=O)C(C)(C)C)CC2)c1 +CNC(=O)Cn1c(-c2ccccc2)nn(-c2ccccc2Cl)c1=O +COc1ccccc1CN(Cc1ccnn1C)CC1CCCO1 +COc1c(CNc2cc(C(=O)N(C)C)ccn2)c(C)nn1C +CCc1onc(C)c1NC(=O)NCCc1cccc(O)c1 +Cc1ccc(C(=O)Nc2ccc3cn[nH]c3c2)cc1 +CN(Cc1ccccc1)c1ccc(C(N)=O)cc1N +Cc1cccc(CN2CC(c3noc(-c4cc(C)n[nH]4)n3)CC2=O)c1 +COC(=O)C1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +Cc1ccc(S(=O)(=O)Cc2noc(-c3ccc(C#N)cc3)n2)cc1 +NC(=O)Cn1c(=O)n(Cc2ccco2)c(=O)c2oc3ccccc3c21 +CN(Cc1cccc(C#N)c1)C(=O)c1ccc(Br)cc1F +COc1cc(C#N)cc(Cl)c1OCC(=O)c1ccccc1 +CNC(=O)c1nccc(Br)c1OC1CC1 +CCCS(=O)(=O)c1ccc(C(=O)c2cccs2)cc1 +Cc1ccc2oc(C(=O)Nc3ccc(N(C)C)nc3)cc(=O)c2c1 +CC(C)C(NC(=O)NCc1ccco1)c1nnc2n1CCC2 +CCOc1cc(NC(=O)C2CCCCN2C(=O)CC)ccc1OC +CCOCCCNC(=O)c1cc2c(=O)n(C)ccc2n1C +CN(C)S(=O)(=O)c1ccccc1-c1ccc(=O)[nH]c1 +COCCN1CC(C(=O)N(C2CC2)C(C)C2CC2)CC1=O +CC(C(=O)c1cccc(Cl)c1)n1cc(Br)cn1 +O=C(NC(c1ccccc1)C1CC1)c1nc2ccccc2c(=O)[nH]1 +NC(=O)c1cccc(S(=O)(=O)Nc2cccc(Cl)c2)c1 +O=C(NCc1cccc(N2CCCC2=O)c1)C1CC1c1ccco1 +N#Cc1ccc(Cn2ccnc2Cc2cccc(N)c2)cc1 +Cc1cc(C)c(NC(=O)CS(=O)(=O)c2ccccc2)c(Cl)c1 +C#CCNC(=O)C(C)Sc1ccc(Cl)cc1 +O=C(NCCn1cccn1)Nc1cccc(Cl)c1 +N#Cc1cc(C#N)c(SCCCC2CCCC2)nc1N +Cn1nc(C(=O)NC2CCN(C(=O)c3ccoc3)CC2)ccc1=O +Cn1cc(C(N)=O)cc1C(=O)Nc1ccc(C(C)(C)C)cc1 +CC1CCN(C(=O)c2cccc(Oc3ccncc3)c2)C(C)C1 +CCCCCc1nnc(NC(=O)CN2CCCCC2=O)s1 +Cn1cc(CC(=O)Nc2nnc(-c3ccsc3)o2)c2ccccc21 +CCOc1ccc(N)cc1CSc1nnnn1C +CC(C)NC(=O)COc1ccc(Cl)c(Cl)c1 +COC(=O)c1ccc(NC(=O)Cn2c(CO)nc3ccccc32)cc1 +O=C(NCc1cscn1)NC1(c2ccccc2F)CC1 +Cc1ccc(F)c(S(=O)(=O)N(C)CCc2ccncc2)c1 +CNS(=O)(=O)Cc1cccc(CNc2ccc(C#N)cc2F)c1 +Cc1ccsc1C(=O)N1CCC(c2n[nH]c3ncccc23)CC1 +O=C(CSc1nnnn1C1CCCC1)c1c[nH]c2ccccc12 +Cn1nnc2cc(C(=O)N(Cc3ccccc3)c3ccccn3)ccc21 +O=C(NCCOc1cccc(Br)c1)c1cnns1 +Cc1cccc(C(=O)N2CCC(C)(O)C(C)C2)c1Cl +O=C(NC1CCCc2nc(-c3cccnc3)ncc21)c1ccsc1 +Cc1noc(C)c1CN(C)C(=O)NCC(C)(C)NS(C)(=O)=O +COc1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1Cl +Cc1cccc(C(=O)N(CC(C)O)CC(C)O)c1 +C#CCSc1nnc(-c2cccc(Br)c2)o1 +CCc1sc(C(=O)NCCOC)cc1Br +Cn1cccc1CN(Cc1cccs1)C(=O)C1CC1 +Nc1ccnc(C(=O)Nc2cccc(Br)c2)c1 +CCNC(=O)COc1ccc(NC(=O)N(C)Cc2ccccn2)cc1 +Cn1cc(C(=O)N2CCCCC2)cc(NC(=O)c2ccncc2)c1=O +CC(C)(C#N)NC(=O)COc1cncc(Br)c1 +CCN1CCN(c2ncc(F)c(N3CCCC3)n2)CC1=O +Cc1ccc(NC(=O)COc2nc3nncn3nc2C)cc1 +COCCNC(=O)Cn1nc(C(F)(F)F)c(Cl)c1C1CC1 +CC(C)Oc1ccccc1C(N)C(=O)NCCCO +Cc1nc2cc(C(F)(F)F)ccc2n1C(C)(C)CO +CC(C)(C)NC(=O)c1ccc(COCC(F)(F)C(F)F)cc1 +NC(=O)c1ccc(C(=O)Nc2c(F)cccc2F)cc1 +CCS(=O)(=O)N(C)Cc1ccccc1OC(F)(F)F +COc1ccccc1C1(CNS(=O)(=O)CC(C)C)CCOCC1 +O=C(NCc1cccc(Oc2ccccn2)c1)C1CCC1 +COc1ccccc1NC(=O)c1cc2c(s1)SCC2 +Cc1ccc(-c2nnc(NC(=O)c3cc(C)n(C(C)C)n3)o2)c(C)c1 +NC(=O)Cc1csc(NC(=O)c2cc(-c3ccccc3F)on2)n1 +COC(=O)c1ccc(NC(=O)c2cscn2)cc1 +CC(=O)Nc1ccc(NC(=O)CNc2ccccc2C(N)=O)cc1 +CC(=O)N1CCC(C(=O)Nc2ccc(F)cc2OCC2CC2)CC1 +CCn1c(N)nc2c1c(=O)[nH]c(=O)n2CCOC +COc1ccc(-c2noc(C(=O)NCc3ccncc3)n2)cc1OC +COCCNC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +NC(=O)NCCc1ccc(C(=O)Nc2ccc3c(c2)COC3)cc1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccc(C(N)=O)cc1 +COC1=CC=C(N2C(=O)CSc3ccccc32)CC1 +CCC(C)NC(=O)c1ccc(CNC(=O)Cn2cnnn2)cc1 +CCN(CC)c1ccc(C(=O)N2CCN(S(C)(=O)=O)CC2)cc1 +CNS(=O)(=O)c1ccc(C(=O)N2CCCC(O)C2)cc1 +Cn1ncc(C#N)c1NCc1c[nH]c2ccccc12 +CC(CNC(=O)C1CCC(=O)N1)c1c(Cl)cccc1Cl +CC(=O)c1ccc(NC(=O)N2CCC(Cc3cnn(C)c3)C2)cc1C +CC(C)CCOCCNc1ncnc2ccsc12 +Cc1ccccc1-c1c(CO)nnn1-c1ccc(C(N)=O)cc1 +O=C(Cn1cccn1)N(Cc1ccco1)CC(F)(F)F +COc1cccc(NC(=O)CSc2nccc(=O)[nH]2)c1 +COC(=O)C(NC(=O)c1coc(-c2ccccc2)n1)C(C)C +CNC(=O)c1ccc(NC(=O)CCCSc2ccccc2)cc1 +O=S(=O)(Nc1ccncc1)c1ccc(O)cc1 +CCC1CN(S(=O)(=O)CCn2cnc3ccccc32)CCO1 +CCN(CC)S(=O)(=O)c1c[nH]c(C(=O)N(C)C)c1 +O=C(NC1CC1)N1CC2CC(C1)CN(C(=O)c1cccc(F)c1)C2 +CC1OCCN(C(=O)Nc2ccc3[nH]c(C(F)F)nc3c2)C1C +CCN(CC)C(=O)NCc1ccnc(OC2CCCC2)c1 +CCn1ncc(-c2cccc3ccccc23)c(C#N)c1=O +Cc1nn(-c2ccccc2F)c(C)c1CC(=O)N1CCC(C(N)=O)C1 +CCc1nnc(CN(C)C(=O)c2c(C)c(C)nc3ccc(C)cc23)o1 +Cc1cc2n(n1)C(C(=O)Nc1ccc(Cl)cc1Cl)CC(O)=N2 +COC(=O)C(NC(=O)c1nc(SC)ncc1Cl)C(C)C +CCOc1cc(C#N)ccc1OCC(=O)Nc1cccc(C(C)=O)c1 +O=c1ccc(-c2ccccc2)nn1CCNc1ncccn1 +CCNC(=O)CNS(=O)(=O)c1ccc(F)c(C#N)c1 +O=C(OCCn1nc2ccccn2c1=O)c1cccc(-n2cccc2)c1 +CCNc1ccc(Br)cc1NC(=O)c1ccnnc1 +CCc1nc2c(NC(=O)Cc3c(F)cccc3Cl)cccn2n1 +CC(C)(C)Oc1cc(CNC(=O)C2CCC(F)(F)CC2)ccn1 +Oc1cccc(C2CN(Cc3ccn(Cc4ccccc4)c3)CCO2)c1 +CC(CO)CNC(=O)Cc1csc2ccc(Cl)cc12 +O=C(Nc1nnc(-c2cccnc2)s1)c1ccccc1F +Cc1ccccc1OCC(=O)N(CCC#N)Cc1ccccc1 +C#CCNC(=O)N(Cc1ccc(C(F)(F)F)cc1)C1CC1 +CCCC(=O)N1CCC(C(=O)NC(C)c2ccccc2)CC1 +c1ccc(C2=Nc3ncnn3C(c3ccco3)C2)cc1 +CC(Oc1ccc2c(c1)CCC2)C(=O)N1CCC(O)CC1 +COc1ccc(C(O)CCC(=O)NC(C)C)cc1N +COc1ccccc1C(=O)Nc1ccc(N2CCCC2=O)c(OC)c1 +CCOc1ccc(-n2ccn(CC#N)c(=O)c2=O)cc1 +Cc1cc(NC(=O)CSc2nnnn2-c2ccc(C)c(C)c2)no1 +COCCn1ccc(NC(=O)c2c(C)cc(C)cc2C)n1 +CC(C(=O)N1CCCC1)N1CCN(CC(=O)Nc2ccccc2)CC1 +Cc1ccccc1Oc1ncccc1CNCc1cnn(C)c1 +CCCc1cc(NCC(=O)NC(C)C)n2nccc2n1 +Cc1occc1C(=O)N1CCC2(CCNC2=O)CC1 +CCCN(CCC)C(=O)CN1CC(CC)Oc2ccc(N)cc21 +CC(C)C1OC2CC3OC(=O)CCC3CC2C1O +Cc1cc(C)n(-c2cc(NCc3ccccc3F)ncn2)n1 +Cc1ccc2c(c1)SC(C(=O)Nc1nc(CC(N)=O)cs1)C2 +Cc1n[nH]c(C)c1NC(=O)CSc1nc2c(cc1C#N)CCCC2 +CN1C(=O)CC(C(=O)Nc2cccnc2)C1c1ccccc1 +Cc1cc(NC(=O)Cc2c[nH]c3ccccc23)n(CCC#N)n1 +COC(=O)CNC(=O)c1cc(Br)ccc1O +CCNC(c1cc(OC)c(OC)cc1Cl)C(F)(F)F +CN1CCc2c(OCC(=O)Nc3ccc(F)cc3)cccc2C1=O +COC(=O)C1(NCc2cc(=O)oc3cc4c(cc23)CCC4)CCCC1 +CC(C)CNS(=O)(=O)c1ccc(Cl)cc1N +Cc1cc(C)c2nc(C)cc(C(=O)NCCSc3cn[nH]n3)c2c1 +CC(CCc1ccccc1)NC(=O)CCc1nc2ncccc2[nH]1 +CS(=O)(=O)c1ccc(-n2cc(-c3ccc4ccccc4n3)cn2)cc1 +Cc1ccc(NCC(O)CO)c(Br)c1 +CCNC(=O)c1cc(S(=O)(=O)NCCOC)ccc1C +CCCc1c(C(=O)Nc2cn[nH]c2)cnn1Cc1ccccc1 +Cc1noc(C)c1C1CCCN1C(=O)NC(C)C +COc1ccc2cc(C(C)C(=O)NCCCC(N)=O)ccc2c1 +CCCNC(=O)N1CCN(Cc2cccs2)CC1 +CN(Cc1ccco1)C(=O)Nc1ccccc1C(F)(F)F +O=c1[nH]c2ccccc2n1CCOc1ccc2ncccc2c1 +Cc1ccc(C(=O)Nc2ccc(OCC#N)cc2)cc1C +C#CCCCOC(=O)c1ccccc1NC(=O)NC(C)C +O=C(CNC(=O)c1ccc(Cl)cc1)Nc1ccccc1 +CCN(CC)c1nc(C)c(-c2nnc(NC)s2)s1 +Cc1cccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)CS3)c1 +COc1ccc(C(C)NC(=O)c2cc(F)ccc2Cl)cc1OC +CN1C(=O)C(Cc2ccc3c(c2)OCO3)Oc2ccc(N)cc21 +COCCNC(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +N#Cc1cccc(C(=O)NCC2(O)CCc3ccccc3C2)c1 +CC1COCCN1C(=O)c1ccc(=O)n(-c2ccccc2)n1 +OCCn1nnc(CO)c1COc1ccc(Cl)cc1 +O=C(NCCc1ccccn1)Nc1ccc(Cl)cc1Cl +COc1ccc(-c2cn3cccc(Br)c3n2)cc1N +COCCN(Cc1ccco1)C(=O)NCc1cccc(Cl)c1 +Cc1nnc(SC(C)C(=O)Nc2nc3ccccc3s2)s1 +NC(=O)NCc1ccc(C(=O)NCc2ccccc2-n2ccnc2)cc1 +O=C(CSc1ccc2nnc(-c3cccnc3)n2n1)N1CCCC1 +Cc1ccccc1C1CC(C)N(C(=O)c2nc3nccc(C)n3n2)C1 +O=C(Nc1cccc(OC(F)F)c1)N1CCCC1 +CC(c1ccccn1)N(C)C(=O)Nc1ccccc1N1CCCC1 +CN(C(=O)CC(O)c1cccc(F)c1)c1ccc2c(c1)CCO2 +Cc1nc2cc(N(C)C(=O)CCc3cncc(F)c3)ccc2[nH]1 +Cn1c(C(=O)NCCc2cccs2)cc2occc21 +CC(C)CNC(=O)c1ccccc1Br +Cc1nc2cc(NC(=O)c3ccc(-n4cccn4)nn3)ccc2s1 +CCN(CC(C)C#N)C(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +N#CCCN(Cc1ccccn1)CC1(CO)COC1 +COc1ccc(CNC(=O)Nc2cc(OC)c(OC)cc2C)cc1F +CCN(CC)C(=O)Nc1ccc(N(C)C(=O)OC)cc1 +CCOc1cccc(C(=O)Nc2ccc(CC(=O)NC)cc2)c1 +CCOC(=O)c1cnn(-c2cccc(C(=O)OC)c2)c1N +COCC(C)N1CCN(C(=O)C(C)(C)c2cccc(F)c2)CC1 +O=C(NC1CCCCNC1=O)c1ccc(Cn2ccccc2=O)o1 +O=C(c1ccccc1-c1ncc[nH]1)N1CC2CC=CCC2C1 +O=C(Cn1nnc(-c2cccs2)n1)N1CCN(C(=O)C2CC2)CC1 +COC(C(=O)N1CCc2sccc2C1)c1ccccc1 +O=C(NCC1CCC1)c1cn(-c2ccccc2)nn1 +COCCOc1nc(C)nc(NCc2ccco2)c1N +CCNC(=O)c1ccc(OCC(=O)NC2CC2)cc1 +O=C(NCC(NC(=O)c1ccc[nH]1)C1CCCCC1)c1ccc[nH]1 +Cc1ccc(CN(C)C(=O)c2cc(S(N)(=O)=O)c(C)o2)s1 +O=C(Oc1ccc(Br)cc1F)C1CCC1 +CN(C)C(=O)C1CCCN1C(=O)COCc1ccccc1 +CNC(=O)c1ccc(NC(=O)NCCC(=O)NC(C)C)cc1Cl +CC1(CNC(=O)NCCc2ccccc2)CCOCC1 +O=C(NCc1cccnc1)c1ccc2[nH]cnc2c1 +Nc1nccnc1C(=O)N1CCN(Cc2ccsc2)CC1 +C=CCn1c(N2CCC(C(=O)NC(C)C)CC2)nc2ccccc21 +COc1cc(C(=O)N2CCOCC2)ccc1OCc1c(C)noc1C +CC(=O)N(Cc1nccn1Cc1ccccc1Cl)CC(C)C +Cn1ccc(NC(=O)c2ccc(NC(N)=O)cc2)n1 +Cc1noc(CCNC(=O)CCc2ccc(Br)cc2)n1 +CC(NC(=O)CCN1CCOC1=O)(c1ccccc1)c1ccccc1 +CC(=O)NCC1Cc2cc(-c3cccnc3)cc(F)c2O1 +O=S(=O)(Cc1ccccc1C(F)(F)F)NCc1cscn1 +CCN(CC)C(=O)CCCNC(=O)N1CCCCCC1 +COc1cccc(CC2CN(C(=O)c3ccc[nH]3)CCO2)c1 +CNc1ncc(C(=O)N2CCCC(CCc3ccccc3C)C2)cn1 +CCC1CCCN(C(=O)c2cc(F)c(F)c(F)c2)C1 +O=C1CCCN1CCCNCc1cc(=O)c2cccc(Cl)c2[nH]1 +CCCS(=O)(=O)c1ccccc1C(=O)NCC(C)C +Nc1nc(N)nc(COC(=O)c2ccc(OCC3CCCO3)cc2)n1 +CCn1ccnc1-c1nccn1-c1ccc(S(N)(=O)=O)cc1 +CCOC(=O)C1CCCN(C(=O)c2ccoc2C)C1 +COC(=O)c1ccc(C)c(S(=O)(=O)N(C)Cc2cc(C)on2)c1 +COCCn1cnnc1SCC(=O)Nc1cccc(Cl)c1C +Cc1cc(CN(C)C(=O)NCc2cccnc2OC2CCCC2)no1 +O=C(NCCNc1ccc(-n2cccn2)nn1)c1cccs1 +CC(C)c1nnc2n1CC(CNc1ccnc(-c3ccccc3)n1)CC2 +O=C(OC1CCN(CC(F)F)CC1)c1cnn2c1CCCC2 +Cc1cc(CNC(=O)c2ccccc2-n2cnnn2)c(C)o1 +CC(NC(=O)c1ccc(-c2cscn2)cc1)C(=O)N1CCOCC1 +Cc1noc(C)c1S(=O)(=O)N(C)CC(=O)Nc1ccc(C#N)cc1 +COc1ccc(C(=O)CN2CCC(=O)CC2)c(OC)c1C +Nc1cc(Cl)ccc1C(=O)OCC(F)(F)F +Cc1ccc(C(O)(CCNC(=O)N2CCOCC2)C(F)(F)F)o1 +CC(=O)c1ccc(OCC2CCOC2)c(Br)c1 +Cc1ccc(NC(=O)Cn2ncc3c(c2=O)N(C)C(=O)CS3)cc1 +Cc1cccc(CN2CCC3(CCN(C(=O)C(C)C)C3)C2=O)c1 +CCOc1ccc(C(C)(C#N)N2CCCCC2)cc1 +O=C(CN1C(=O)CNc2cc(F)ccc21)c1ccccc1 +CCn1cc(C(=O)NC2CC3CCC2(C)C3(C)C)cn1 +Cc1nnc(SCC(=O)Nc2ccc(OC(F)(F)F)cc2)s1 +O=S(=O)(Cc1ccccc1)NCCOc1ccc(F)cc1 +CC1CCCC(CNC(=O)C2CC(=O)N(Cc3ccccn3)C2)C1 +CC(=O)N1CCN(Cc2nc(-c3cc(F)ccc3F)cs2)CC1 +COCCCNC(=O)C(C)NC(=O)N1CCn2c1nc1ccccc12 +COc1ccc(C(O)C2CC(=O)N(CCC(C)C)C2)cc1 +Cc1ccsc1CNC(=O)Nc1ccnn1C1CCCC1 +OCCc1csc(COc2cccc3cccnc23)n1 +CCc1ccc(OC(=O)c2cc3c([nH]c2=O)CCCC3=O)cc1 +Cn1nc(-c2cccc(Cl)c2)c2c1CCCC2=O +Cc1c(C(C)O)cnn1-c1nc2ccccc2s1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)Nc2cc(C(C)C)no2)c1C +COC(=O)c1cc(-c2cc(OC(C)C)ccc2O)nn1C +Cc1n[nH]c(SCC(=O)N2CCN(c3ccccc3)C(=O)C2)n1 +Cc1ccc(NC(=O)C2CC3CCC2O3)cc1C(=O)NC(C)C +CCOC(=O)CCNS(=O)(=O)c1ccc(C)cc1 +Cn1cc(C2CN(S(=O)(=O)Cc3ccccc3F)CCO2)cn1 +CC1CC1CNC(=O)NCc1nc2ccccc2[nH]1 +CCOc1ccc(C(C)NC(=O)C2CCOCC2)cc1 +CCCn1nccc1NC(=O)c1ccc(OC)c(OC)c1 +Cc1c(C(=O)N2CCOCC2)oc2c(C)cccc12 +Cn1ncc(-c2ccc(F)cc2)c(C(N)c2ccccc2)c1=O +COCCNC(=O)C1CC(=O)N(CCc2ccccc2)C1 +Cc1cc(C(=O)NCC(=O)N2CCOCC2C2CC2)c(C)o1 +Cc1noc(C2(NS(=O)(=O)c3ccc(C#N)cc3)CCCCC2)n1 +Cc1ccc(C(N)=O)cc1NC(=O)c1ccc(-c2cscn2)cc1 +Cc1nc(C(C)(C)NCc2cnc(N3CCOCC3)nc2)sc1C +Cc1c(F)cccc1N1CCC(C(=O)NCC(C)C)C1=O +COCc1cccc(CNC(=O)c2ccc(C)s2)c1 +COc1ccc(-c2nnc3sc4c(n23)CCCC4)cc1N +Cn1cccc1C1CCCN1C(=O)c1cccc(O)c1 +Cc1ccc(C(=O)COc2ccc(S(C)(=O)=O)cc2)cc1C +CCN(CC)C(=O)c1ccc(NCC(=O)Nc2ccccc2)cc1 +COc1cccc(C(C)NCCc2nccs2)c1 +CC(C)(C)Nc1ncnc(Nc2ccccc2)c1N +Cc1noc(C)c1CNC(=O)c1ccc(COc2ccccc2)o1 +CC(C)Oc1ccc(CNC(=O)NCc2cc(C(C)C)no2)cc1 +Cc1cccc(CCCOC(=O)c2cnn(-c3ccccc3)c2)n1 +O=C(Cn1cccn1)NCC#Cc1ccccc1Cl +CNc1ccc(C(=O)NCCCc2ccccn2)cn1 +O=C(NCc1ccc2nonc2c1)c1cn2ccsc2n1 +Cc1noc(C2CN(S(=O)(=O)N(C)C)CC23CCOCC3)n1 +Nc1ccc(F)c(S(=O)(=O)NCc2ccccc2)c1 +CC(C)(C)OC(=O)N1CCCC1C(=O)NCc1ccccc1F +CCOC(=O)CNC(=O)c1nccc2c(N)c(C)ccc12 +Cc1nn(C)c(C)c1OC(=O)c1ccnc(OC2CCC2)c1 +Cn1cnnc1SCC(=O)Nc1ccc2oc3ccccc3c2c1 +Nc1c(C(=O)Nc2cccc(F)c2)oc2cccnc12 +CC(C)CNC(=O)c1[nH]cnc1C(=O)NCC1CC1 +CC(C)c1nnc(S(=O)(=O)CCOC2CCCCCC2)n1C +CCOC(=O)c1cc(C)c(C)c(S(=O)(=O)N(C)C)c1 +CCC(CC)C(NC(=O)NCc1ncn(C)n1)c1ccccc1 +N#Cc1ccc(COc2cccc(-n3cncn3)c2)c(F)c1 +CC1CCN(C(=O)C(C)Sc2nnnn2C)CC1 +COC(=O)CN(Cc1ccc(Cl)c(C)c1)C1CCOCC1 +CC(Oc1ccc(C(=O)c2ccccc2)cc1)C(=O)N1CCOCC1 +COc1ccccc1-n1nnc(C#N)c1C1CCCCC1 +Cc1ccc(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)c(=O)[nH]1 +Cn1c(CCC(=O)Nc2c[nH]c3ccccc23)nc2ccccc21 +COCc1ccc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)o1 +O=C(c1ccc2cc[nH]c2c1)N1CC(c2nc(-c3ccccn3)no2)C1 +COC(=O)C(C)(C)NC(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +COc1cccc(-c2ccc(N)c(=O)n2C(C)C)c1 +Cc1cc(C(F)(F)F)nn1-c1ccc(NC(=O)C2CC2)cc1 +Cc1csc(NC(=O)c2cc(Cl)ccc2N)n1 +O=C(CCn1c(=O)[nH]c2ccccc2c1=O)NCc1cccnc1 +c1cc2c(cc1-c1nnc(C3CCCC3)o1)CCCN2 +COc1ccc(CC(=O)Nc2c(C)cc(C)nc2C)cc1 +Cc1cccnc1C(NC(=O)c1ccncc1F)C(C)C +Cc1cc(C)c(C(=O)CN2C(=O)c3ccccc3S2(=O)=O)c(C)c1 +O=C(CCC1CCCO1)Nc1nnc2ccccn12 +Cc1cnccc1-n1nc(C(C)C)nc1-c1ccc(C#N)nc1 +CNC(=O)CN1CCN(C(=O)CCn2cc(C)cn2)CC1 +CCN(Cc1ccccn1)C(=O)NCCc1cccc(O)c1 +O=C(Nc1ccccc1-n1cncn1)c1cnccn1 +CN(Cc1ccccc1Cl)C(=O)c1cccnc1OCC(F)F +Nc1ccc2c(c1)OC(c1ccccc1)C(=O)N2CC(O)CO +CC1CC1C(=O)Nc1nnc(SCc2ccc(C#N)cc2)s1 +CN1CC2(CCN(C(=O)c3cn4cc(Cl)cnc4n3)C2)OC1=O +Cc1noc(-c2ccc(C(=O)NC(C)CC(N)=O)cc2)n1 +N#CC1(NC(=O)CCCNC(=O)c2ccco2)CCCCC1 +CCn1nc(NC(=O)c2ccco2)c2cc3cccc(C)c3nc21 +Cc1cc(NC(=O)c2csc(Nc3ncccn3)n2)no1 +COc1ccc(C(N)=O)c(OS(=O)(=O)N(C)C)c1 +CC1CC2CCCCC2N1C(=O)C1CN(C)CCO1 +Cc1nc(-c2ccccc2)c(C(=O)NC(C)C2CC2)s1 +Cn1c(=O)c2c(n3ncnc13)NC(=O)CC2c1ccccc1F +COCCNC(=O)Cc1cnn(-c2ccccc2)c1 +CC(Nc1ccc(C#N)cn1)c1ccc(NC(=O)C2CC2)cc1 +CCCCN(C)C(=O)CN1CCCOc2ccc(N)cc21 +Cc1nnc(CCCN2CCN(C(=O)c3ccoc3)CC2)o1 +O=C(CNC(=O)c1ccsc1)NCc1cccc2ccccc12 +Cc1noc(Cn2cnc3c(oc4ccccc43)c2=O)n1 +CNC(=O)c1cccc(-n2cc(Br)cn2)c1 +C=CCNC(=O)c1cc2sccc2nc1C(F)(F)F +CC(=O)NC(C)(C)c1noc(C=Cc2ccc(C)cc2C)n1 +CCNC(=O)CN(CC)S(=O)(=O)c1ccc(C(C)=O)cc1 +CN1C(=O)c2oc3ccccc3c(=O)c2C1c1ccccc1F +Brc1cc2c(cc1Br)OCO2 +COC(=O)c1ccc(CNC(=O)c2ccccc2)cc1 +O=C(Nc1ccccc1)NC1CCc2c(F)cccc21 +CC(NC(=O)c1ccc(F)c(N)c1)c1ccccc1 +O=C(C1CC1)N1CCCC(OCc2cc(F)ccc2F)C1 +Cc1cc(NC(=O)c2ccccc2F)ccc1S(N)(=O)=O +Cc1ccc(F)c(-c2nc(-c3ccncc3)no2)c1 +O=C(Nc1cccc(COCC2CC2)c1)Nc1ccccn1 +Cc1cc(=O)oc(C)c1C(=O)N1Cc2cnc(-c3ccccc3)nc2C1 +COCCOc1cc(NC(=O)N2CC(C)CCC2C)ccc1OC +COc1ccc(NC(=O)CCc2nc3ccccc3[nH]2)cc1Cl +Cc1nn(-c2ccccn2)c2ncc(C(=O)c3ccccc3O)cc12 +CC(NC(=O)NCCO)c1ccc(NC(=O)C2CC2)cc1 +CCNC(=O)C1CCN(S(=O)(=O)c2cc(Cl)ccc2C)CC1 +O=C(NCc1cccnc1)Nc1ccccc1Oc1cccc(F)c1 +CN(c1ccc(C(=O)NC2CC3CCC2C3)cc1)S(C)(=O)=O +CNc1nc(SCCS(=O)c2ccccc2)nc2ccccc12 +COC(=O)c1sc(NC(=O)C2CCC(F)(F)CC2)nc1C1CC1 +CC(c1ccc(Cl)cc1)N1CCN(Cc2ccnn2C)CC1 +C=CCNC(=O)N(CC)Cc1c(F)cccc1F +COc1ccc(Cl)cc1CC(=O)Cc1csc(C)n1 +Cc1ccc(CN(C)C(C(=O)N(C)C)c2ccccc2)cc1 +CCCNS(=O)(=O)c1ccc(OCC)c(-c2nc(C)no2)c1 +CCCc1nnc(NC(=O)c2ccc(N3CCOC3=O)cc2)s1 +Fc1cccc(Cl)c1Cc1nnc(SCc2ccncc2)o1 +COC(Cn1cnc2ccncc2c1=O)c1cccs1 +O=C(NC1CCCCNC1=O)c1cccc(-n2cccn2)c1 +NC(=O)C(OC(=O)CCc1ccc2c(c1)OCCO2)c1ccccc1 +CC(NC(=O)Nc1cccc(Cl)c1)c1ccccn1 +COc1ccc(S(=O)(=O)CCC(=O)N2CCNC(=O)C2C)cc1 +CCCc1cc(=O)n2nc(-c3ccncc3)nc2[nH]1 +O=C(c1ccc2ccccc2c1)N1CCCC1c1ccc[nH]1 +COc1cccc(C(NC(=O)c2ccccc2)c2nccn2C)c1 +Cc1cc(C(=O)N2CCN(CC(=O)N(C)C3CC3)CC2)on1 +Cc1nc2ccc(C(=O)NC3(C(N)=O)CCCC3)cc2nc1C +CC(=O)Nc1cc(C(=O)N2c3ccccc3OCC2C)ccc1F +CCc1noc(C)c1NC(=O)CN(CCc1ccccc1)C(C)=O +O=C(CCNS(=O)(=O)c1cccc(Cl)c1)N1CCOCC1 +O=C(OCC(=O)N1CCCC1)c1ccccc1F +CC(C)CNC(=O)C1CCCN(C(=O)c2ccc3ncnn3c2)C1 +CC(C)NC(=O)c1cccc(S(=O)(=O)NCc2cccs2)c1 +Cc1ccc(F)cc1C(=O)Nc1ccccc1C#N +CC(C#N)N(C)S(=O)(=O)c1cccc(Cl)c1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1cccc(COC(C)C)c1 +O=C(Cc1ccon1)Nc1ccc(-n2ncc3ccccc32)cc1 +N#Cc1cccc(C(=O)N2CC(OCC3CC3)C3COCC32)c1 +CC(=O)N1CCC(NC(=O)Nc2cn[nH]c2)CC1 +Cc1cccc(NC(=O)Cc2nc(Cc3ccccc3)n[nH]2)c1 +CC(C)(C)c1ncc(C(=O)NCc2nc(-c3ccccc3)no2)cn1 +COC(=O)Nc1ccc(CNC(=O)NC2CCCC2)cc1 +CCCC1CN(C(=O)Nc2ccc(F)cc2C#N)CCO1 +Cc1ccc(OCCC(=O)Oc2ccc(-n3cnnn3)cc2)c(C)c1 +CCn1cnnc1CNC(=O)c1ccc2c(c1)nnn2CC +CN(C)C(=O)CC(NC(=O)NCCc1ccccc1)c1ccccc1 +COc1ccc(F)cc1CN1CCc2cc(S(N)(=O)=O)ccc21 +COCc1ccc(C2CCCN2C(=O)NCC2(C)CCCO2)o1 +COC(C(=O)N1CCC(Oc2ccccc2)CC1)c1ccccc1 +Cc1ccc(C2(O)NC(=O)C(C)C2n2nnc3ccccc32)cc1 +CC(C)(C)c1n[nH]c(SCC(=O)NC2(C#N)CCCCC2)n1 +Cc1ccc2nc(NC(=O)c3ccc4c(c3)OCCO4)sc2c1 +CC(C)CCCC(C)NC(=O)Cn1c(=O)oc2cccnc21 +CCn1nc(C)cc1C(=O)N(C)c1ncnc2ccsc12 +Cc1cc(C(=O)NCc2cccc(OC(F)(F)F)c2)c(=O)[nH]c1C +CC(=O)Nc1ccc2c(c1)CN(S(=O)(=O)c1ccc(C)cc1)CC2 +COc1ccc(Cl)cc1C(O)CNC(=O)c1cccs1 +O=C(COC(=O)C1COc2ccccc2O1)Nc1cccc(F)c1 +O=C(Cn1cc(Br)ccc1=O)N1CCCCC1 +O=C(C1CC1)N1CCSc2ccc(Cl)cc21 +COC(=O)c1c(SCc2csc3ccccc23)nc(=O)[nH]c1C +CC(C)N1CC2(CCN(C(=O)c3cccnc3)CC2)c2ccccc21 +O=C(CSc1nnc2n1CCCCC2)NCC1CCCO1 +COc1cc(OC)c(OC)cc1CN1C(C)COCC1C +CC(=O)Nc1ccc(Nc2cc(C#N)ccn2)cc1 +Cn1ccnc1SCC(=O)c1c[nH]c2ccccc12 +O=C(NCc1ccccn1)c1csc(-c2ccco2)n1 +CCn1ncc2cc(C(=O)NCc3ccccn3)c(N)nc21 +Cc1ccc(NC(=O)c2c[nH]c3c(C(F)(F)F)cccc3c2=O)cc1 +O=C1c2ccccc2-c2n[nH]c(=O)c3ccc(N4CCCC4)c1c23 +COc1ccc(-n2nnc(C(=O)Nc3ccccc3)c2C)cc1Cl +CC(=O)Nc1ccc(F)c(NC(=O)c2ccccc2C)c1 +Cc1cnn(-c2ccc(C(=O)N3CCCC3Cn3cccn3)cc2)c1 +Nc1c(-c2ccccc2)nc2scc(-c3ccccn3)n12 +CC(OC(=O)c1cccnc1)C(=O)c1cccc(Cl)c1 +CC(=O)N1CCCCC1c1nc(-c2cccnc2)no1 +COc1ccc(CC(=O)N(CCO)CCO)cc1 +CC(C)CC(C)(NC(=O)C1COc2ccc(F)cc2C1)C(N)=O +c1ccc(OCc2noc(COc3ccc4ncccc4c3)n2)cc1 +O=c1nc(Nc2ccc3c(c2)OCCO3)sc2ncccc12 +Cc1ccnc(NC(=O)c2occc2-c2ccccc2)c1 +CC1(C)CN(C(=O)c2ccc(Cl)cc2O)CCC1(C)O +CCN(C)c1ccc(C(=O)NCC2COCCO2)cc1 +Cc1nn(C)c(C)c1CN(C)C(=O)c1cc(C(F)(F)F)n(C)n1 +COCc1ccc(CNC(=O)Nc2cnc3c(c2)c(C)nn3C)cc1 +CN(C)C(=O)c1ccc(Cl)c(NC(=O)C2CCC2)c1 +Cc1cc(C)n(C(=O)C(C)n2nc(C(F)(F)F)cc2C)n1 +CCS(=O)c1ccccc1C(=O)N1CCCC1 +CCC(CC)C(=O)N1CCCC1CS(=O)(=O)c1ccccc1 +O=C(c1cccc(-c2cn[nH]c2)c1)N1CCOC(C(F)(F)F)C1 +CN(C(=O)CCOc1ccccc1)C(C#N)c1ccccc1F +CCSc1cc(C(=O)Nc2cc(C)ccn2)ccn1 +CCC(CO)(CO)NC(=O)c1cc(C)c(F)cc1F +CC(=O)N1CC2CCCN(S(=O)(=O)c3cccs3)C2C1 +COc1cccc(N2CC(NC(=O)c3ccco3)CC2=O)c1 +Cc1cc(C)n(-c2ccc(COC(=O)CCC3CCCO3)cc2)n1 +COc1cc2c(c(OC)c1OC)C(=O)NC(C)(C)C2 +COc1ccc(S(=O)(=O)Nc2cccc(C(C)=O)c2)cc1 +COc1ccc(C(C)C)cc1-c1cnn(CCC#N)c1 +Cc1ccc(NC(=O)Cc2c(C)noc2C)c(Br)c1 +CN(C)C(=O)CSc1nc(-c2cccs2)ccc1C#N +Cc1ccc(-c2nc(C(=O)OCCc3cccnc3)cs2)o1 +CN(CC1CCCN1c1cccnn1)c1ncccc1C#N +COC(=O)c1ccc(Cl)c(CN2CCOC(c3cnn(C)c3)C2)c1 +CCN(CC)C(=O)Cn1cnc2c(sc3nc(C)c(C)cc32)c1=O +COc1ccc(S(=O)(=O)N(C)c2c(C)noc2C)c(C)c1F +Cc1cc(=O)oc2cc(OC(C)C(=O)Nc3nncs3)ccc12 +Cc1cccc(OCc2nc3ncc(N)cc3[nH]2)c1C +COC(=O)C1CCCCCC1NC(=O)c1occc1Br +NC(=O)C1CCN(C(=O)Nc2ccc(F)cc2F)C1 +COC(=O)CCCC(=O)c1ccc2c(c1)NC(=O)C(C)O2 +CCC(C)(C)NC(=O)CS(=O)(=O)c1cccc(C)c1 +CC(C)Cc1nc(C2CCOC2)n(-c2ccc(F)cc2)n1 +Nc1ccc2c(c1)[nH]c(=O)c1ccc(Br)cc12 +Cn1c(C(=O)NC2CCCC2)nc2ccc(O)cc21 +CCCOc1ncccc1CNC(=O)c1ccnc(-n2cncn2)c1 +O=C(CCc1ccccc1F)Nc1ccnc2ccnn12 +N#CC1(C(=O)N2CCC(OCCc3ccccc3)CC2)CCCCC1 +O=C(Cn1cc(CCO)nn1)Nc1cccc(Cl)c1 +CCOCCC(=O)Nc1nn(-c2ccccc2Cl)cc1C +CC(=O)N1CC(C)Sc2ccc(S(=O)(=O)N3CCCC3)cc21 +CC(C)N(CCC#N)C(=O)CCCc1cccs1 +Cn1cc(NC(=O)C2CCC(NC(=O)CC3CCCCC3)CC2)cn1 +CCOc1ccccc1OCC(=O)Oc1ccccc1 +COc1cccc(NC(=O)N2CCN(C(=O)c3nonc3N)CC2)c1 +Nc1ccc(-c2ncc(-c3cccc(F)c3)o2)cn1 +Cc1nc(C(=O)NCCC(=O)N2CCOCC2)cs1 +Cc1cccc(C)c1NC(=O)c1ccc(=O)n(Cc2ccccc2)n1 +O=C(Cc1n[nH]c2ccccc12)N1CCc2cc(F)ccc2C1 +O=C(CNC(=O)c1c[nH]nc1-c1ccccc1F)OC1CCCCC1 +O=C(NCCc1nc2ccccc2[nH]1)c1c[nH]c2ccccc2c1=O +CC(NC(=O)NC(C)(C)c1cccc(F)c1)C(C)N1CCOCC1 +CCCC(=O)N1CCCC(C(=O)Nc2cc(C)on2)C1 +CN(Cc1ccc(F)c(F)c1)C(=O)CCCCNC(N)=O +COc1ccccc1C(=O)C1CCCN(C(=O)c2snnc2C)C1 +CC(=O)Nc1cc(S(=O)(=O)Nc2cc(C)ccc2O)ccc1F +O=C(CCCc1nc2ccccc2c(=O)[nH]1)NCc1ccccc1 +COc1ccc(Nc2nc(N)nc(C(F)(F)F)n2)c(OC)c1 +Nc1nc(COC(=O)COc2ccc3c(c2)CCC3)nc2ccccc12 +COc1ccc(Cl)cc1NC(=O)N1CCC12CCC2 +Cc1ccc(-c2ncco2)cc1NC(=O)NCCC1CC1 +CNC(=O)C1CCC(NC(=O)NCCCOC)CC1 +Cn1nc(C(C)(C)C)cc1NC(=O)NCC1(C(N)=O)CCOCC1 +Cc1scc(C(=O)NC2CCCc3ccccc32)c1C +COC(=O)Nc1cccc(NC(=O)c2ccc(C)[nH]c2=O)c1 +CN(C)C(=O)CCc1ccc(NC(=O)Cc2ccc(Cl)cc2)cc1 +Cc1cc(NCc2nc(CC(C)C)no2)ccc1C(=O)N(C)C +O=C(CCc1cccs1)N1CCC2(CCCN(CCO)C2=O)C1 +COC(=O)CCC(=O)NCc1ccc2ccccc2c1 +CC(c1ccc(S(N)(=O)=O)cc1)N(C)Cc1cccc(C#N)c1 +CNC(=O)c1ccc(NC(=O)CNc2ccccc2)cc1 +CC(=O)N1Cc2ccc(C(O)c3ccc(F)cc3)cc2C1 +COc1cc2c(cc1Br)CCNC2C1CC1 +COc1ccccc1CN(C(=O)c1cccc(OC)c1F)C1CC1 +CCOC(=O)C(N)c1cc(C(F)(F)F)nn1C +COc1ccc(Cl)cc1S(=O)(=O)NCCn1nc(C)cc1C +CC(=O)N1CCN(C(=O)COc2ccc(Cl)c(Cl)c2)CC1 +CCc1ccsc1C(=O)NC1CCN(C(=O)c2ccncc2)CC1 +OCCn1c(-c2cccc(F)c2)nc2cc(F)ccc21 +COc1cc(C(=O)NCc2ccc(C)c(F)c2)ccc1OCC(N)=O +Cc1nc(C)n(C2CCCN(C(=O)c3c[nH]cn3)C2)n1 +Cc1cc(C(=O)Nc2ccc(N3CCOCC3)cn2)c(C)n1C(C)C +CC(NC(=O)c1csc(-c2ncccn2)n1)c1ccncc1 +COC(=O)CN1CCN(c2cccc(F)c2C(C)=O)CC1 +CC(NC(=O)c1csnn1)C1(N2CCOCC2)CCCC1 +COc1cc2c(c(OC)c1OC)CCNC2c1cc[nH]c1 +CCCc1ccc(NC(=O)c2cccnc2N)cc1 +Cc1c(Br)c(C(=O)N2CCC3(CC2)OCCO3)nn1C +N#Cc1ccc(OCCCn2nnc3ccccc3c2=O)cc1 +CC(C)NS(=O)(=O)Cc1ccc(CNC(=O)C2CCCO2)cc1 +CCCC(C)(C)NC(=O)NCC(C)(C)c1ccncc1 +CC(=O)Nc1ccc(C)c(NC(C)C(=O)N(C)Cc2ccccc2)c1 +C=CCCCN(C)C(=O)c1ccc(Cl)cc1O +Cc1ccoc1C(=O)N1CCC(OCc2ccccc2F)CC1 +CCCCCNC(=O)c1cn(-c2ccc(F)cc2)nn1 +O=C(c1ccc(Br)cc1)N1CCC(C(F)(F)F)CC1 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CN(C)C(=O)Cn1cc(C(=O)NC(c2ccccc2)C(C)(C)C)nn1 +CCN(CC)C(=O)CC(C#N)C(=O)N(CC)CC +Nc1c(NCc2ccco2)ncnc1N1CCc2ccccc2C1 +CC(Oc1cccc(F)c1)C(=O)Nc1cc(N2CCCCC2)ncn1 +Cc1cc(C)cc(NC(=O)Cn2ccc3c(=O)n(C)c(=O)n(C)c32)c1 +CCn1c(C(=O)N(C)CC(=O)N(C)C)cc2ccccc21 +CCc1ccc(NC(=O)CCC(=O)Nc2nnc(C(C)C)s2)cc1 +COc1ccc(C(C)N(C)C(=O)c2ccccc2OC)cc1 +CC(NC(=O)C(C)(C)C)C(=O)Oc1ccc(Cl)cc1 +N#Cc1ccccc1NC(=O)c1cc(Cl)c2c(c1)OCCO2 +CCOC(=O)c1c(C)c(S(=O)(=O)N2CCCCC2)c(C)n1C +CC(C)c1cc(C(=O)N2CCN(c3ccc(F)cc3)CC2)no1 +CCN(CC(=O)OC)C(=O)Cc1csc(C)n1 +CC(=O)c1ccc(NC(=O)c2ccc3nnc(C)n3c2)cc1 +O=C(CSc1ccccc1Cl)NCc1nc[nH]n1 +CCN(Cc1ccccc1)C(=O)c1c(C(C)C)nn2ccccc12 +CN(C(=O)c1ccc(N2CCNC2=O)cc1)c1ccc(F)c(F)c1 +C#CCN1CCN(CC(=O)Nc2cc(C)c(C(=O)OCC)s2)CC1 +Cc1nc(C(F)(F)F)c(NC(=O)OC(C)(C)C)s1 +Cc1n[nH]cc1NC(=O)C(C)n1cnc2ccccc21 +CCOC(=O)C1CCN(S(=O)(=O)c2c[nH]c(C(=O)OC)c2)CC1 +Cc1ccc(NC(=O)CNC(=O)C2CCCCC2)nc1 +Cc1nc(NC(=O)c2cccs2)sc1C(=O)N(C)C +CNc1nc2c(OC)c(OC)c(OC)cc2s1 +Cc1cc(C(C)NC(=O)NC(CCO)c2ccccc2)c(C)o1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1csc(-c2ccsc2)n1 +COc1cc(C2CC(=O)Nc3c2c(C)nn3C)cc2c1OCO2 +O=C(NCc1ccc(CN2CCOCC2)cc1)c1ccc(F)c(F)c1 +CC(C)=CC1C(C(=O)N2CCN(c3cnccn3)CC2)C1(C)C +CCn1nnnc1-c1cccc(NC(=O)N(C)CCC#N)c1 +Cc1cc(NC(=O)c2ccc3c(c2)OCO3)c2ncccc2c1 +COc1cc(C#N)ccc1OCC(=O)Nc1ccc(F)cc1F +CC(=O)Nc1cccc(-n2cnnc2SCc2cc(C)on2)c1 +Oc1ccc2c(c1F)C(c1ccc3cc[nH]c3c1)NCC2 +C=CCNC(=O)NCC(C)(OC)c1ccccc1F +COc1ccccc1NC(=O)CCn1ccc2ccccc21 +CCOc1ccccc1C1NCCc2cc(F)c(O)cc21 +CC(C)C(NC(=O)c1ccco1)C(=O)NC1CC1 +Cn1ncnc1CNc1cc(F)ccc1Oc1ccccc1 +CCN1CC(C(=O)Nc2cccc3ccccc23)CC1=O +O=C(Nc1ccccc1O)c1cc2c(nc3sccn32)s1 +CCCC(C)N(C)C(=O)Nc1cccc(C(C)=O)c1 +CCC(NC(=O)c1cnc(C)[nH]c1=O)c1ccc(S(C)(=O)=O)cc1 +CC(=O)Nc1cc(NC(=O)NCc2ccc(C)s2)ccc1Cl +COCc1cccc(C(=O)Nc2cccc(-c3nnnn3C)c2)c1 +CC(=O)N(Cc1ccc(NC(=O)NCc2cnn(C)c2)cc1)C1CC1 +COc1ccc(Cc2nc(C)cc(N)n2)cc1Cl +NC(=O)c1ccc(OCC(=O)Nc2nc(-c3ccco3)cs2)cc1 +Cc1cc(CNc2ncccc2Cl)ccc1F +N#Cc1c(F)cccc1NCc1nnc2n1CCC2 +CCOCC1CCCN(C(=O)NCCCN2CC(C)OC(C)C2)C1 +O=C(C#Cc1ccccc1)N1CCC(CCC(=O)N2CCCC2)CC1 +CC(O)CN1CCN(C(=O)Cc2cnn(-c3ccccc3)n2)CC1 +CC(Nc1ncnc2[nH]cnc12)c1ccccc1Cl +CCOc1c(Cl)cc(CNS(=O)(=O)C(C)C)cc1OC +COc1cc(F)c(C(C)NC(=O)CC(C)C)cc1OC +O=C(NCCC(=O)N1CCCC1)NCc1cccc(OC(F)F)c1 +CCOC(=O)C1=C(N)C(=O)N(Cc2ccccc2)C1 +Cc1cc2c(cc1O)C(CSc1ncccn1)NCC2 +Cc1c(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)oc2ccccc12 +CC(=O)Nc1ccc(S(=O)(=O)Oc2ccc(C)c(C)c2)cc1 +CCCCn1nc(-c2ccccc2OC(C)C)cc(N)c1=O +O=C(COc1ccccc1)NCC#CCOc1ccccc1F +COCc1nc(COc2cc(C)cc(C)c2)sc1C#N +CN1C(=O)COC2CN(C(=O)c3ccccn3)CC21 +O=C(C1CCCO1)N1CCC(Cc2nncn2-c2ccccc2)CC1 +C=CCNC(=O)CSc1nc2ccccc2c(=O)n1CCC +O=C(C1CCCC1)N1CCN(Cc2cnn(-c3ccccc3)c2)CC1 +Brc1ccccc1-c1nc(-c2ccncc2)no1 +CN(CCc1ccccn1)C(=O)CN1CCCCCC1=O +Cc1oc(-c2ccccc2Cl)nc1CN(C)CCc1cnn(C)c1 +CCC1CCc2sc(C(=O)N(C)Cc3cnn(C)c3)cc2C1 +CCOCCOCC(=O)N1CCCN(C(=O)c2cccc(C)c2)CC1 +Cc1cc(CCNC(=O)c2cccc(C#N)c2)on1 +COC(=O)c1ccc(S(=O)(=O)NCc2ccco2)n1C +Cc1ccc(CS(=O)(=O)N2CCc3ccccc32)cc1 +CCCN(Cc1ccccc1)S(=O)(=O)c1cccc(C(N)=O)c1 +COc1c(Cl)cccc1NC(=O)COc1cccc(C(C)=O)c1 +Cn1ccsc1=NC(=O)CSc1nnnn1C1CC1 +CCn1cc(NC(=O)NC(C)c2ccc(C)c(F)c2)ccc1=O +COc1ccc(CNC(=O)CCc2ccc(C3CC3C)o2)cc1 +CC(NC(=O)c1ccc(N)cc1F)C1CCCCC1 +Cc1ccc(-c2ccc(CO)o2)cc1NC(=O)c1cccnc1 +CC(C)(NC(=O)Nc1ccc2c(c1)COC2)c1nccs1 +O=C(NCCc1ccccc1Cl)c1cccc(-n2cccn2)c1 +NC(=O)c1cccnc1N1CCN(c2nccs2)CC1 +C=CCn1nc(C)c(CCC(=O)N2CCCCC2C)c1C +CC(C)NC(=O)c1ccccc1NC(=O)c1cc(C(C)(C)C)n[nH]1 +CN(C)C(C(=O)N1CCNCC1)c1c(F)cccc1Cl +COCc1nc2ncc3c(=O)n(-c4ccccc4C)ccc3n2n1 +Cc1csc(CNC(=O)N(C)CC(=O)NC(C)(C)C)n1 +Cc1nc(N2CCCC2)nc2c1CCN(C(=O)c1cccn1C)CC2 +COc1ccc(CC(=O)N2CCNC(=O)C2(C)C)cc1 +CCOc1ccc2nc(-c3ccc(N)c(OC)c3)[nH]c2c1 +Cc1ccc2nc(CNC(=O)c3cccnc3)cn2c1 +COC(=O)c1cc(S(=O)(=O)NCC2CCCO2)c[nH]1 +C#CCn1c(CN(C)C(=O)c2ccccn2)nc2ccccc21 +O=C(Cc1cccc2ccccc12)Nc1ccc2c(c1)NC(=O)CO2 +Cc1cc(CN(C)C(=O)Cc2nc(-c3cccs3)oc2C)no1 +CCCN1C(=O)C(Cc2ccccc2)Oc2ccc(O)cc21 +COCCN(Cc1ccc(C#N)cc1)C(=O)c1cc(C(C)C)[nH]n1 +C=CCN(C(=O)C(C)OCC(F)(F)F)c1ccccc1 +COc1cccc(-c2ccc(=O)n(CC(=O)Nc3nncs3)n2)c1 +COC(=O)CCC(=O)Nc1ccc(OC)c(Cl)c1 +Cc1ccc(-c2nc(CC(=O)N3CCCc4ncccc43)cs2)o1 +CCOc1ncccc1CNC(=O)c1sc(C(C)C)nc1C +O=C(NC1CC1)c1occc1CS(=O)(=O)c1ccccc1 +Cc1ccccc1NC(=O)C(C)OC(=O)c1cccc(O)c1 +COc1cccc(CSc2cc(-c3ccccn3)nc(C)n2)c1 +Cc1cccc(CNC(=O)NC2CCN(S(C)(=O)=O)CC2)c1 +CCn1cc(C(=O)Nc2ccc(Cl)cc2F)cn1 +CN(C)S(=O)(=O)c1cccc(NC(=O)C(C)(C)C)c1 +Nc1c(-c2ccc(F)cc2)nnn1-c1cccc(Cl)c1 +C=CCNC(=O)NC1CCN(c2ccccc2C(=O)NCCC)CC1 +Cc1cc(C(=O)CCc2nc(-c3cccs3)no2)c(C)s1 +Cc1cc(C)cc(OCC(=O)Nc2cc(N3CCCCC3)ncn2)c1 +O=c1ccccn1CCCCNS(=O)(=O)c1cccnc1 +CCOc1ccc(C)cc1S(=O)(=O)N1CCCCC1 +N#Cc1c(-c2ccncc2)nc2sc(-c3ccccc3)nn12 +CNC(=O)c1ccc(Cl)cc1NC(=O)c1cc(C)sc1C +Cc1ccc(N2CC(C(=O)NCC(N)=O)CCC2=O)cc1C +CCCc1noc(CSc2n[nH]c(=O)n2C)n1 +O=C(NCc1cccnc1)c1cc(-c2ccccn2)nc2ccccc12 +CC1CCCC(OC(=O)CCSc2nnnn2C)C1 +CC1CCCN(C(=O)NCc2cccc(S(N)(=O)=O)c2)C1 +COCCCNC(=O)Nc1ccc(C)cc1Cl +Cc1nn(CC(=O)N2CCCCC2C(N)=O)c(=O)c2ccccc12 +Cc1cc(C(=O)Nc2ccc(F)cc2)c2c(=O)n(C)c(=O)n(C)c2n1 +NC(=O)c1ccc(NC(=O)Cn2cc(-c3ccccc3)ncc2=O)cc1 +O=C(NCCc1ccccc1)c1cc(F)ccc1F +Cc1nn(C)c(NC(=O)c2ccc(Cl)cc2)c1Cl +Cc1ncccc1-n1cccc1C(=O)NCCN1CCOCC1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)c1cc(C)n(C2CC2)c1C +CCC1CN(CC(=O)NC(C)c2ccco2)CCO1 +COc1ccc(Cl)cc1NC(=O)n1ccnc1 +N#Cc1cccc(C(=O)N2CCOC3CCCC32)c1 +Cc1cc(C(=O)NC2CC2c2ccccc2)ccc1-n1cncn1 +NC(=O)CNC(=O)c1cc(Br)ccc1O +CC(C)C(C)(CNC(=O)OC(C)(C)C)NC(=O)Nc1nccs1 +O=C1CCN(C(=O)c2cc(-c3ccccc3)nc3ccccc23)CCN1 +Cc1cc(-c2nnc(NC(=O)c3cc4ccccc4o3)o2)n(C)n1 +c1ccc2sc(N3CCCC3Cn3cncn3)nc2c1 +COC(=O)C(C)NC(=O)C(CC(C)C)NC(C)=O +Cc1ccc(Cl)cc1NCC(=O)c1c(N)n(C2CC2)c(=O)[nH]c1=O +CC(=O)NCCNC(=O)NCCC(=O)NC1CCCCC1 +O=C(Nc1ccnn1C1CCCCC1)c1cc(=O)[nH]c2ccccc12 +CC(=O)N1CCN(CC(c2ccccc2)c2ccccc2)CC1 +Cc1noc(C)c1C(C)NS(=O)(=O)c1ccc(F)c(F)c1F +Cc1ccc2c(c1)oc(=O)n2CCNC(=O)C(C)(C)C +C=CCn1c(C)cc(C(=O)CSc2nnc(C3CC3)n2C)c1C +CS(=O)(=O)NCCNC(=O)CCc1cccc(F)c1 +Cc1nnc(N2CCOC3C(Oc4ccccn4)CCC32)s1 +CN(C(=O)Cc1csc(Cc2ccccc2)n1)C1(C#N)CCC1 +CS(=O)(=O)Nc1ccccc1C(=O)Nc1ccc(F)c(Cl)c1 +CC1CCCCN1C(=O)NCCc1cnn(-c2ccccc2)c1 +C#CCN1CCC(C(=O)NCCc2cc(C)cc(C)c2)CC1 +CN(C(=O)c1ccc2c(c1)SCC(=O)N2)c1ccccc1 +C=CCOC(C)C(=O)Nc1ccc(C(=O)OC)cc1 +CC(C)NC(=O)N(C)Cc1ccc(Br)cc1 +Cc1ncc(C(=O)NC2(c3cccc(F)c3)CCCC2)c(C)n1 +CN(CC(=O)NC1CC1)C(=O)c1cc(C2CC2)nc2ccccc12 +COc1ccc(NC(=O)C2(C#N)CCCC2)c(Cl)c1 +O=C(c1cncnc1)c1ccc(Cl)cc1Cl +COC(=O)CCCOc1ccc2ccncc2c1Br +Fc1ccc(COc2ccccc2-c2nc[nH]n2)c(F)c1 +CN(C)c1nc(Cn2cnc(C3CCC3)cc2=O)ns1 +COC(=O)NCC(=O)N(Cc1ccccn1)C(C)C +CCOc1ccccc1-c1cccc(C(=O)NC2CN(C(C)=O)C2)c1 +COC(=O)c1cc(N)cn1Cc1ccc(F)cc1F +Cc1nc(C)c(CNCCc2ccc(F)cc2C)s1 +O=C1CCC(C(=O)NC23CC4CC(CC(C4)C2)C3)N1 +Cc1ccnc(NC(=O)C(NC(=O)c2ccccc2)C(C)C)c1 +CCN(Cc1cnc2ccccn12)C(=O)c1cc(C2CC2)on1 +Cc1nn(C)c(C(=O)Nc2cnn(C)c2C(N)=O)c1Br +COCCCNC(=O)c1cc(OC)c(OC)cc1C +NC(=O)C1CCCN(c2ccc(C(=O)OCc3ccoc3)cc2)C1 +CCOC(=O)C=C(Nc1ccc2cnn(C)c2c1)C(F)(F)F +CCOc1ccccc1CNc1cccc(C#N)c1 +COc1ccc(OC(F)F)c(NC(=O)NC(C)C(C)C)c1 +Cc1ccc(CC(=O)N2CCCc3c(cnn3C)C2)cc1 +CC(=O)c1cccc(S(=O)(=O)NCc2ccccc2)c1 +NC(=O)c1cccc(C2CCN(c3cnccn3)CC2)n1 +CCCCCC(=O)Nc1ccc2c(c1)OCCCO2 +COc1ccc(OC)c(CN(C(=O)c2ccc(F)cc2F)C2CC2)c1 +Cc1ccc(CN(C(=O)NCc2ncn(C)n2)C2CC2)cc1C +CC(Oc1cccc(Cl)c1)C(=O)N1CCN(c2ncccn2)CC1 +CC(=O)N1CCC(NC(=O)NCCOC2CCCCC2C)CC1 +Cc1ccccc1NC(C)c1cccc(-n2cnnn2)c1 +O=C1N(Cc2ccc(F)cc2)CCN1c1ccc(C(F)(F)F)cn1 +Cc1ccc2cccc(C(=O)NCCCOC3CCCC3)c2n1 +Cc1cc(C)n(NC(=O)C2CC(=O)Nc3ccccc32)c(=O)c1 +CC1(C)Cc2ccccc2CN1C(=O)c1ccccc1 +CC(C)C(=O)Nc1cccc(NC(=O)c2ccco2)c1 +CCn1c(C(C)O)nc2cc(C(F)(F)F)ccc21 +Nc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)nc1 +CC(=O)Nc1ccc(OC(=O)c2ccc(NC(=O)C3CC3)cc2)cc1 +CCS(=O)(=O)c1ccccc1C(=O)Nc1cccnc1OC +CCOC(=O)CN(C(=O)c1cccc(F)c1)C1CC1 +Cc1oc(C(=O)NCCCC(C)(C)C)cc1S(N)(=O)=O +Cc1cc(C(=O)COC(=O)c2cc(=O)c3ccccc3o2)c(C)n1C +CCn1ncc(Br)c1C(=O)Nc1cc(F)ccc1C +Cc1ccc(CNC(=O)c2sc(N3CCCC3=O)nc2C)o1 +COCCCN(C)C(=O)Nc1ccc(OCC#N)cc1 +COC(=O)Nc1ccc(NC(=O)C2Oc3ccccc3OC2C)cc1 +CCN(CC(=O)NC(C)C)C(=O)CCc1ccc(F)c(F)c1 +CNC(=O)c1n[nH]c2c1C(c1ccc(-c3cc[nH]n3)o1)CC(=O)N2 +CCCN(C)C(=O)C1CCCN(c2cnn(C)c(=O)c2)C1 +CNCC(=O)OCc1ccc2c(c1)C(C)(C)C(=O)N2 +CC(C)(C)c1ccc(NC(=O)c2ccncc2)cc1 +COc1cc(CNc2ccc(NC(C)=O)cc2)c(SC)cc1OC +CN(C)c1ncc2cc(Br)ccc2n1 +O=C(Nc1ccccc1)c1cccn(Cc2ccc(F)cc2)c1=O +CCn1c(=O)c(C)nc2cc(C(=O)NC3CCCCNC3=O)ccc21 +Cc1nc(NCCCO)c2cccc(N)c2c1Br +CCCOCCNC(=O)Nc1cccc(OC)c1Cl +CC(=O)Nc1ccc(Cc2nc(C3CC3)no2)cc1 +CC(=O)Nc1ccc(C(=O)N2CCc3ccc(Cl)cc3C2)cc1 +COC(=O)C1(NC(=O)Cc2cccs2)CCC(C)CC1 +Cc1cc2c(NCCCO)nc(-c3cccnc3)nc2s1 +Cc1nc(C(C)(C)NC(=O)CCCc2cccs2)sc1C +COCCOC(=O)c1sc2nc(N)[nH]c(=O)c2c1C +Cc1nc(C2CCCN(C(=O)C3Cc4cccc(F)c4O3)C2)no1 +COc1ccc(-c2c(S(C)(=O)=O)nsc2S(C)(=O)=O)cc1 +COC(=O)CN(C(=O)c1ccc(C(F)(F)F)nc1C)C(C)C +Cc1nn(-c2ccccc2)c(C)c1C1CC(O)=Nc2c1cnn2C(C)C +O=C(CSc1nc(C2CCCO2)n[nH]1)c1ccc2c(c1)OCO2 +COc1ccc(C(=O)NCCc2csc(C)n2)cc1 +Cc1cccc(C(=O)Nc2cccnc2-n2ccnc2C)c1 +CC(=O)c1c(C)[nH]c(C(=O)NCCc2nc(C)no2)c1C +CC(=O)NC(c1cccc(S(C)(=O)=O)c1)c1cc(F)ccc1F +Cc1cccc(NC(=O)NCC(=O)N2CCCC2c2ccccc2)c1 +Cc1cc(C)n(-c2ccc(CCNS(=O)(=O)N3CCCC3)cc2)n1 +COCCCC1CCCN(C(=O)c2ccc(C)cc2F)C1 +COCCCNC(=O)Nc1cccc(-n2nnnc2C)c1 +NC(=O)COc1ccc(NC(=O)NC2CCCc3ccccc32)cc1 +CCc1noc(CC)c1CNC(=O)c1ccc(N2CCCC2)nc1 +CC(=O)Nc1ccc(NC(=O)C2(c3ccccc3)CCOCC2)cc1 +CCCC(C)NC(=O)C(C)Sc1ncccc1Cl +CC(C)C(=O)Nc1cccc(-c2nnnn2C2CC2)c1 +COc1ccc(CN(C)C(=O)Cn2c(C)nc3ccccc32)cc1F +CN(Cc1ccccc1)C(=O)c1cn(C)nc1C(C)(C)C +COC(=O)CC1Oc2ccccc2N(CCCn2cnnn2)C1=O +CN(C)c1ccc(C(=O)NCC(=O)c2cccs2)c(F)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1ccc(C)cc1O +O=C(NCCNC(=O)C1c2ccccc2Oc2ccccc21)C1CC1 +CCCC(=O)NCC(=O)N(CC)C(C)c1cc2ccccc2o1 +Cc1nc(CC(=O)OCCc2c[nH]nc2C(F)(F)F)cs1 +COc1ccc(CNc2c(C)nn(C)c2C)cc1F +O=C(NC1CC1)C1(c2cc(-c3ccccc3)on2)CC1 +CCc1ccccc1CNC(=O)Nc1cccc(C(=O)NC)c1C +COc1cc(C(C)=O)cc(-c2cnn(C)c2)c1OC +CCn1c(=O)c2c(nc(SCCc3ccccc3)n2C)n(C)c1=O +Cn1nc(C(=O)N2CCCC(CCc3ccc(F)cc3)C2)ccc1=O +O=C(c1ccccc1)c1cccc(C2OCCCO2)c1 +CCOC(=O)CCC(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O +COc1ccc(N(C)C(=O)Cn2nnc3ccccc32)cc1OC +CN(C)C(=O)CCCC(=O)NCc1cc(F)ccc1Br +COC1CC(=O)OC(c2ccccc2)(c2ccccc2)C1 +Cn1cnc2cc(C(=O)NCc3csc(=O)[nH]3)ccc21 +CCN(CC)C(=O)COc1cccc(NC(=O)c2ccc(F)cc2)c1 +Cc1ccc(S(=O)(=O)N(C)c2cccnc2)cc1 +COc1cc(NC2CCN(C(C)=O)CC2)cc(OC)c1 +O=C(Cn1nnc(-c2cccc(F)c2)n1)NC1CCCC1 +C=CCNS(=O)(=O)c1cnn(C(C)CC)c1N +O=C(NCCNC(=O)c1ccoc1)Nc1cccnc1 +CCC1c2ccsc2CCN1C(=O)Cc1cn2ccsc2n1 +Cc1ccccc1CNC(=O)CNC(=O)c1ccsc1 +O=C(Cn1ccccc1=O)N1CCCC1Cc1ccccc1 +Cc1ccc(C(C)NC(=O)CCn2c(C)csc2=O)cc1F +Cc1noc(C2CC3CN(C(=O)c4cnccn4)CCC3O2)n1 +CC(=O)c1ccc(NC(=O)N(C)CC(=O)Nc2ccccc2)cc1 +Cc1ccoc1C(=O)N1CC2CCCC2(COCc2cccnc2)C1 +COc1ccc(C(C#N)CC(=O)NCc2ccc(C)cc2)cc1 +C#CCN(CC#C)C(=O)c1ccc(Oc2ccccc2C#N)c(Cl)c1 +COc1ccc(-c2ncn(CCO)c(=O)c2C#N)cc1 +Cc1cc2nn(-c3ccc(F)cc3)nc2cc1NC(=O)c1cccnc1 +Cn1cc(CCC(=O)NCc2ncc(-c3ccccc3)[nH]2)cn1 +C#CCN1CCN(C(C)C(=O)NCc2cccc(OC)c2)CC1 +CCC(=O)N1CCCCC1C(=O)Nc1ccc(F)c(NC(C)=O)c1 +Cc1cccc(OCCC(=O)NCc2ccc3c(c2)OCCO3)c1C +CCNc1nnc(S(=O)(=O)CC(=O)N2CCC(C)CC2)s1 +Cc1cccc(CNC(=O)C(Cc2ccccc2)NC(N)=O)c1 +Fc1cc(CNCCc2nnc3n2CCC3)ccc1-n1cncn1 +O=C(Nc1ccc2c(c1)Cc1ccccc1-2)c1ccncc1 +C#CCNC(=O)CC1OC(CNC(=O)c2ccco2)C(O)C1O +CCCCc1nc2cc(C(=O)N3CCC(OC)CC3)ccc2o1 +CCNC(=O)CCCOc1ccc(Cl)cc1Cl +OCCCn1c(Cc2ccccc2)nc2ccccc21 +Cc1n[nH]c(C)c1-c1c(C)c(-c2cnn(C)c2)nc(N)c1C#N +Cc1cc(C)cc(NC(=O)C2CC(=O)n3ncnc3N2)c1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3cccn3C)c2)n1 +CSc1nnc(NCC(=O)c2ccccc2)s1 +CCc1noc(CNc2cc(Cl)ccc2Cl)n1 +Cc1ccc(CNC(=O)NCc2cnc(C)s2)c(OC(C)(C)C)c1 +COc1ccccc1C(O)CCCC(=O)Nc1ccccc1 +CCC1CN(C)c2ccccc2CN1C(=O)CNC(=O)NC +O=C(NCCO)c1ccc(-c2ccc(Br)cc2)o1 +CNS(=O)(=O)c1cccc(CNC(=O)c2ccc3[nH]cnc3c2)c1 +CCc1nnc(SCCC(=O)Nc2ccc(F)cc2)n1N +COc1cn(-c2ccccc2)nc1C(=O)NCc1cc2ccccc2o1 +CCNC(=O)NCCOC(=O)C1(c2ccccc2F)CC1 +CC(Nc1ccn(Cc2ccccn2)n1)C(=O)NC(C)(C)C +COCCOc1cc(NC(=O)c2cc(C)ccc2C)ccc1OC +CC(NC(=O)c1nc(-c2cnccn2)no1)c1ccccc1 +CCCCNC(=O)C1CCCN(C(=O)C2(c3ccccc3)CCC2)C1 +CCOC(=O)c1sc(CC(C)C)nc1C(F)(F)F +Cc1ccsc1CNC(=O)Cn1cccnc1=O +O=C(Nc1nccs1)N1CCc2cc(Br)ccc21 +O=C(c1ccc2c(c1)OCCO2)N1CCC(O)(c2cccnc2)CC1 +O=C(NCc1cccnc1-n1ccnc1)c1ccc2ccccc2n1 +CC(C)(C)CN(C(=O)c1ccco1)c1ccncc1 +CCc1ccc(OC)c(S(=O)(=O)NCCO)c1 +CCOc1cccc(CNC(=O)CN2CCOC3CCCCC32)c1 +CN(C)c1cccc(NC(=O)c2nccc3c(N)cc(F)cc23)c1 +COCc1c(C(=O)N2CCCC(O)(CO)C2)noc1C +CCN(C)c1ccc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)cc1 +CCCS(=O)(=O)NCC1(O)CCc2ccccc2C1 +O=C(NCc1ccccn1)c1nc2ccccc2c(=O)[nH]1 +CCc1ccc(NC(=O)N2CCN(Cc3ccncc3)CC2)cc1 +CCC(C)(C)NC(=O)C1CC(=O)Nc2cc(F)ccc21 +Cc1cc(C(=O)NC2(CNC(=O)OC(C)(C)C)CCCC2)n(C)n1 +CCCNC(=O)c1cncc(-c2cccc(NC(=O)CC)c2)c1 +Cc1noc(CC2CC3CN(C(=O)c4cccnc4)CC3O2)n1 +Cc1ccc(NC(=O)CCc2nc(-c3ccc(C)[nH]c3=O)no2)cc1 +CCNC1=C(C(=O)Nc2ccccc2)S(=O)(=O)c2ccccc21 +O=C(CSc1ccc(-c2ccco2)nn1)NCc1ccco1 +CCOC(C)C(=O)Nc1c(-c2ccccc2)nc2ccccn12 +Cc1nn(C)c(NC(=O)c2cccc(NC(=O)c3ccco3)c2)c1C +CS(=O)(=O)c1cc(S(=O)(=O)NCc2cccs2)ccc1F +CC(NC(=O)NCc1ccc(C#N)cc1)c1cccc(N2CCCC2)c1 +N#CCCN(CCC#N)C(=O)c1ccc(Br)c(F)c1 +O=C(CSc1ccncc1)Nc1ccn(-c2ncccc2Cl)n1 +CC(C)(C)OCC(O)CN1CCN(CC(=O)N2CCCC2)CC1 +CN(CCC(O)c1ccccc1)C(=O)c1cc(Cl)c[nH]1 +O=C1N(c2cccnc2)CCN1c1ccc2sccc2c1 +CC(C)CCOC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +Cc1c(Cl)cccc1NC(=O)c1cnc2ccccn2c1=O +CC1CCCCN1C(=O)C1CCC(=O)N1Cc1ccco1 +OCCc1csc(COc2ccc(F)cc2)n1 +O=C(NCc1ccc(C(F)(F)F)cc1)c1ccc(C(F)(F)F)nc1 +Cc1cc(CN2CCN(C(=O)CN3CCCC3=O)CC2)on1 +O=C(CSc1nnnn1-c1ccc(O)cc1)NCC(F)(F)F +Cc1ccc(-c2n[nH]c(NC(=O)CCOC(C)C)n2)cc1 +Cc1cccc2c1CCN2c1ncnc2c1cnn2C +CC(=O)NCC1CCN(C(=O)NC2CCCC2)CC1 +CN(CCOc1cccc(Cl)c1)c1nc2[nH]ncc2c(=O)[nH]1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2cccc(C(=O)NC3CC3)c2)c1C +Cc1ccc(C2=CC(=O)Nc3ncccc3N2)cc1 +COc1ccc(-n2nc3cc(C)c(NC(C)=O)cc3n2)cc1Cl +NC(=O)c1ccc(NC(=O)CCCC2CCCCC2)cc1 +CCOC(=O)c1ccsc1NC(=O)Cc1ccc(F)cc1 +Cn1cnnc1-c1cccc(NCc2ccc(OCC(F)F)cc2)c1 +O=C(c1ccc(C(F)(F)F)cc1)N1CCC(Nc2cccnc2)CC1 +CCCCC(=O)Nc1ccc(NC(=O)c2ccc(F)cc2)nc1 +COCc1nn(CCOc2ccccc2C)c(=O)o1 +Cc1cc(Br)ccc1N(C)S(=O)(=O)N(C)C +CSc1cc2c(cc1NC(=O)NC(C)C(C)C)OCCO2 +CC1(c2ccccc2F)NC(=O)c2ccccc2N1 +COCCOC(=O)c1cccc(-n2ccnc2SC)c1 +Cc1ccc(OCC2CCCN(C(=O)CCCn3cncn3)C2)cc1 +O=C1CCCCCN1CCCNc1nc2ccccc2s1 +Cc1cc(C)cc(OCC(=O)N2CC(C(N)=O)Oc3ccccc32)c1 +CC(C)N1CC(C(=O)NCCCN(C)S(C)(=O)=O)CC1=O +COCCNC(=O)C1CCC(C)N(S(C)(=O)=O)C1 +CN(C)c1ccc(S(=O)(=O)N2CCCCC2)cn1 +Cc1ccc(S(C)(=O)=O)cc1NCC(=O)NC1(C#N)CCCC1 +CCCNC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +CNC(=O)c1cc(C)ccc1NC(=O)c1ccc(C)cc1C +COCc1nc(Cc2c(F)cccc2Cl)no1 +CCC(C)(NC(=O)c1ccc(S(=O)(=O)NC)cc1)C(=O)OC +CCN(CC(=O)OC)C(=O)CCc1cccnc1 +COc1ccc(Cl)c(NC(=O)CCn2c(C)csc2=O)c1 +Cc1cc(C)c(OCC(=O)NCC(=O)Nc2nccs2)c(C)c1 +CCc1nnc(NC(=O)c2cc(C)sc2C)s1 +CC(C)Cc1cc(NC(=O)c2n[nH]c3ccccc23)n(C)n1 +COc1ccc(C2Cc3ccccc3C(=O)N2)cc1 +CCN(CC)S(=O)(=O)c1cccc(NC(=O)c2cnc(C)cn2)c1 +O=S(=O)(NCCCC1CCCC1O)c1c(F)cccc1Cl +CCCNC(=O)c1cnn(-c2ccccc2)c1-n1cccc1 +COC(=O)c1conc1-c1cccc(Br)c1 +COCc1ccc(S(=O)CC2CCCC2)cc1 +Cc1cc(C(=O)OCC(=O)Nc2ccccc2F)c2ccccc2n1 +CCC(CO)NC(=O)CC(C)c1cccc(OC)c1 +Cc1cc(C(=O)NCc2cnn3ccccc23)c(C)o1 +CCN(CCO)C(=O)c1ccc(-n2ccnc2)nc1 +Cn1ccc(NC(=O)C2(c3ccc(F)cc3)CCOCC2)n1 +Cc1cc(C)cc(-c2cc(C3CCOC3)c(C#N)c(N)n2)c1 +COc1ccc2c(=O)c(C(=O)Nc3nnc(C4CC4)s3)c[nH]c2c1 +CCCC(C#N)NC(=O)c1cccc2c1OCCO2 +Clc1cnn(Cc2cc(-c3ccccc3)on2)c1 +NC(=O)c1ccc(NC(=O)N2CCCN(CC(F)F)CC2)c(F)c1 +COc1cc(C(=O)N2CCN(c3cnccn3)CC2)ccc1C +CN(CC1CC1)C(=O)NC1CCN(C(=O)c2ccccc2F)CC1 +COc1cc(-c2nc(SC)n[nH]2)cc(OC)c1OC +Fc1cccc2[nH]c(CSc3nnnn3C3CCOCC3)nc12 +CN(C(=O)c1ccccn1)c1ccc2ccccc2c1 +COc1cccc(OC)c1OCC(=O)NCC(C)C +Cc1cc(N(C)CC2CC(=O)N(C3CCCC3)C2)n2nccc2n1 +CC1C(=O)NCCN1c1nc(-c2ccncc2)nc2c1cnn2C +Cn1c(SCC(=O)N2CCCCC2)nc2ccccc2c1=O +CCCC(C)NC(=O)Cn1nnc(-c2ccccc2Cl)n1 +CC1CCCN(S(=O)(=O)NCC2(C(N)=O)CCOCC2)C1 +O=C(NCCc1cccnc1)Nc1nnc(C2CC2)s1 +CCC(C)(C)NC(=O)c1cc(=O)c2ccccc2[nH]1 +N#Cc1ncn(CC(=O)c2ccc3c(c2)Cc2ccccc2-3)n1 +Cc1cccc(-c2nc(N)nc3c2CN(C(=O)c2ccncn2)C3C)c1 +Cc1cc(C)c(C)c(S(=O)(=O)NCCCN2CCCC2=O)c1C +O=C(NC1CCCc2ccccc21)N1CCN(c2ncccn2)CC1 +Cc1cc(OCC(=O)NCc2ccc(Br)cc2F)no1 +COC(=O)Nc1cccc(NC(=O)c2cn[nH]n2)c1 +CCS(=O)(=O)N1CCCc2cc(Br)ccc21 +Cc1noc(CNC(=O)C2CN(C(=O)COc3ccccc3F)C2)n1 +O=C(Nc1ccccc1)N1CCC(c2nc(-c3ccccc3)n[nH]2)CC1 +CCc1ccccc1CNC(=O)c1c(C)nsc1NC +Cc1ccccc1C1(CNC(=O)NC(C)c2nnc3n2CCC3)CC1 +COc1ccc(C(C)=O)c(OCc2cscn2)c1 +CC(Sc1ccc(Br)cc1)C(=O)Nc1ncccn1 +CC1CCCN(C(=O)CN2C(=O)COc3ccc(Cl)cc32)C1 +CC(C)CCC(=O)N1CCN(C(=O)Cc2c(F)cccc2F)CC1 +Cc1c(CNc2cccc3c2CCCC3)cc(C#N)n1C +NC(=O)C1CCN(C(=O)c2cccnc2-n2cccn2)c2ccccc21 +O=C(Nc1cccc(Cl)c1-n1cccn1)c1cnccn1 +Cc1ccc(S(=O)(=O)NCCc2ccccn2)cc1 +COc1cccc(C(=O)NCc2ccccc2-n2ccnc2)c1O +COC(=O)c1ccc(S(=O)(=O)N(Cc2ccccc2)C(C)C)o1 +CC(C(=O)Nc1cccc(O)c1)n1c(=O)oc2ccccc21 +Cc1cccc(C(=O)Nc2ccnn2Cc2ccccc2)n1 +COC(=O)c1ccc(C(=O)NC2(c3noc(C)n3)CCCC2)nc1 +CC(NC(=O)COc1cccc2c1CCC2=O)c1cccs1 +COc1ccc(C)cc1NC(=O)Nc1ccc(C)cn1 +Cc1nn(CCC(=O)N2CCC(C)CC2)c(C)c1Cl +CCCc1c(C(=O)N(C)Cc2noc(C)n2)[nH]c(C)c1C(=O)OC +O=C(CCNS(=O)(=O)c1cccnc1)Nc1cccc(F)c1 +C=C(C)Cn1c(SCCCCC)nc2c1c(=O)[nH]c(=O)n2C +CC(Oc1ccccc1C(N)=O)C(=O)Nc1ccc(F)cc1Cl +Cc1cnn(C2CCCC2)c1NC(=O)NCCCNc1cccnc1 +CCOC(=O)C1CCN(C(=O)c2cc(C)cc(C)c2)CC1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cn(C)nc1C(C)(C)C +CC(C)Oc1ccccc1CS(=O)(=O)c1ccccc1 +CC(C)c1nc(S(=O)(=O)NCc2cn(-c3ccccc3)nn2)c[nH]1 +C=C(C)CSc1nc(C(C)(C)C)nc2c1c(=O)n(C)c(=O)n2C +CCC(=O)N1CCCC(C(=O)Nc2cc(C#N)ccc2Cl)C1 +CC(C)c1ccc(OCC(=O)NCC2CCCO2)cc1 +CN(C)C(=O)CN1C(=O)C(c2ccccc2)Oc2cc(N)ccc21 +CCOCCCNC(=O)c1cc2c(C)nn(C)c2nc1N +CC(C)NC(=O)CCc1nc(-c2ccc3cc[nH]c3c2)no1 +CCOC(C)C(=O)Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1 +CC(C)c1ccnc(NCCC(=O)NC2CCCCC2)n1 +CC1CN(C(C)C(=O)NC(C)c2ccccc2)CC(C)O1 +N#Cc1cccc(NC(=O)CNC(=O)c2ccc(Cl)cc2Cl)c1 +Cc1ccc(N2CCC(NC(=O)COc3ccccc3)C2=O)cc1 +Cc1c(C(=O)N2CCOc3ncccc32)cnn1-c1ccncc1 +CNC(=O)c1cc(NC(=O)C2CCCC2)ccc1Cl +CCn1c(C)cc(C(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)c1C +CC(C)CNC(=O)c1c2c(nc3ccc(F)cc13)CCC2 +COC(=O)C1(NC(=O)Cc2c[nH]c3ccccc23)CCCCC1 +COCCN(CCC#N)Cc1cnc2ncccn12 +CNC(=O)c1csc(-c2cccc(OC)c2OC)n1 +CCCCN(C(=O)c1cc(S(C)(=O)=O)ccc1Cl)C(C)CC +COc1cccc(NC(=O)CSc2nc(N)cc(=O)[nH]2)c1 +O=C(NCc1nncn1C1CC1)Nc1cccc(Br)c1 +O=S(=O)(Nc1cccc(F)c1)c1c[nH]c2ncccc12 +O=c1[nH]c2ccc(Cl)cc2c(=O)n1CC1CC1 +O=C(Nc1ccc2c(c1)C(=O)NCCO2)c1ccccc1Cl +Brc1cccc(COC2CCOCC2)c1 +CCNC(=O)Cn1c(CCNC(=O)CC)nc2ccccc21 +O=C(Nc1nnc2ccccn12)c1ccccc1F +COc1ccc(-c2cc(C(=O)OCC(N)=O)c3ccccc3n2)cc1 +O=c1[nH]c2c(Br)c(Br)ccc2s1 +Cn1cc(C(=O)N2CCN(CC(=O)N3CCCCC3)CC2)cn1 +CNC(=O)c1cccc(CCNC(=O)c2ccc(O)cc2F)c1 +CCOC(=O)C1CCCN(C(=O)CN(C)C(=O)c2ccco2)C1 +Cc1cc(S(=O)(=O)NC(C)C)ccc1OCC(N)=O +O=C(Cc1ccc(O)cc1)NCCCSc1ccc(F)cc1 +CCC(C)Oc1cccc(NC(=O)c2csc(C)n2)c1 +COc1ccc(S(=O)(=O)NCc2ccoc2)cc1Cl +Cc1ccc(C(=O)Nc2sc(C)c(C)c2C(=O)OC(C)C)o1 +CN(Cc1ccccc1)c1ncnc2c1nc1n2CCCC1 +COCCNS(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +COc1ccc(C(=O)NCC2CC(=O)N(Cc3ccccc3)C2)cc1 +NC(=O)c1ccc(=O)n(Cc2ccc(SC(F)F)cc2)n1 +C=CCOc1cc(C(=O)NCCN2CCOCC2)cc2occc12 +CC(NC(=O)c1cc(Br)cs1)c1ccncc1 +CCN(CCNC(=O)c1ccc(NC(C)=O)cc1)c1cccc(C)c1 +O=C(NCc1ccc(F)cc1F)Nc1cnccc1C(F)(F)F +CCn1c(=O)c(=O)n(CC(=O)NC2CCCCCC2)c2ccccc21 +Cn1ccnc1N1CCN(C(=O)c2ccc3ccccc3c2)CC1 +CCC(=O)N1CCCC1c1cccc(Nc2nc(C)cc(C)n2)n1 +Cc1ccc(CC(=O)N(C)CCCc2ccccc2)cn1 +CCC(CC)NC(=O)CNc1ccc(OC)nc1 +Cn1ccc(CN2CCCN(c3cccnn3)CC2)c1 +CCN1C(=O)Cc2cc(C(O)c3ccc(C)cc3)ccc21 +CCCCNC(=O)C1CCCN(C(=O)NCC(C)C)C1 +Cc1ccc(CN(C)C(=O)c2cnccn2)c(C)c1 +Cc1ccc(NC(=O)Oc2ccc3c(c2)ncn3C)cc1C +Cn1nnc2cc(C(=O)N3CCN(C4CCCC4O)CC3)ccc21 +CC1CC(C(=O)NC(C)c2cccc(C(F)(F)F)c2)CCO1 +Cc1cc(C(=O)NCCCN(C)S(C)(=O)=O)on1 +O=C(NCCC1=CCCCC1)C1CCN(C(=O)NC2CC2)CC1 +COc1cccc(CNC(=O)c2cc3occc3n2C)c1 +O=C(NCc1ccncc1)c1ccccc1OCC1CCCO1 +O=c1onc(-c2cccs2)n1CC1(CO)COC1 +CC(Oc1ccc(F)cc1)C(=O)NC1CCN(S(C)(=O)=O)CC1 +CC(Oc1ccccc1C#N)C(=O)OCC(=O)N1CCCCCC1 +OCC(CNc1cnc2ccccc2n1)Cc1ccccc1 +CCC(C)NC(=O)NC1CC(C)(C)Cc2oc(C)cc21 +CC(C#N)CN(C)C(=O)c1cc(Br)ccc1Cl +CC(C)CCC(NC(=O)C1COCCO1)C(C)(C)C +CCCNC(=O)CNC(=O)Cn1cnc2ccc(F)cc2c1=O +CC(=O)N1CCCC1C(=O)NCC1(c2ccccc2)CC1 +COC(=O)c1cc(-c2ccc(Cl)cc2Cl)n2ncc(C#N)c2n1 +O=c1cc(NCc2ccccc2)c2ccccc2[nH]1 +O=S(=O)(N1CCCC1)N(CCO)C1CCCC1 +CCOC(=O)c1c(C)[nH]c(C)c1-c1ccccc1OC +CCNS(=O)(=O)c1ccc(Cl)cc1C(F)(F)F +Cn1cccc(NC(=O)c2ccn(-c3cccc(F)c3)n2)c1=O +CCC(C)NC(=O)Nc1ccc(C(=O)OC)cc1 +C=CCN(Cc1ccc(OC)cc1)C(=O)NC(C)C +CC(=O)Nc1ccc2nc(NC(=O)c3ccc(C)cc3Cl)oc2c1 +O=C(Cc1ccccc1F)NC1CCCN(c2ccccc2F)C1=O +CCSc1cccc(C(=O)Nc2nnc(-c3ccco3)o2)c1 +COCCN(CCC#N)S(=O)(=O)c1ccc(F)c(Cl)c1 +O=C(Cc1csc(Cc2ccc(F)cc2)n1)NCc1cscn1 +Cc1ccc(CCS(=O)(=O)c2ccc3c(c2)OCCCO3)cc1 +CCC(C)(C)NC(=O)COC(=O)c1cc(C)ccc1NC(=O)N(C)C +COCC(=O)N1CCC(C(=O)NCc2cc(C)nn2C)CC1 +CCCn1c(CCCO)nc2cc(Cl)ccc21 +COc1ccc(-c2cc(C)nc(N)n2)c(OC)c1C +CCOc1cc(N2CCCC(CNC(=O)OC(C)(C)C)C2)ncn1 +COc1cccc(CNC(=O)c2nc3c(Cl)cccn3c2C)c1 +CC1(COC(=O)CCC(=O)c2ccc(F)cc2F)COC1 +CCc1onc(C)c1NC(=O)NCC(C)Sc1ccccc1 +Cc1cc(C(=O)Nc2ccccc2F)c(C)n1-c1nccs1 +CC(C)CC(C)(C#N)NC(=O)CCn1cnc2ccccc2c1=O +O=c1cc(C(F)(F)F)nc(CNc2ccc(-n3cncn3)cc2)[nH]1 +CCOc1ccc(NC(=O)N(C)CC(O)COC)cc1Cl +Cc1ccc(F)cc1NC(=O)CNC(=O)C1CCCC1 +Nc1ncc(Cl)c(N2CCc3ccc(Br)cc32)n1 +CCNC(=O)NC1(C(=O)NCc2cccc3ccccc23)CCCC1 +Cc1cn(C2COC3COC(c4ccccc4)OC3C2)c(=O)[nH]c1=O +CN(Cc1cccc(Cl)c1)C(=O)c1cn(C)c2ccccc12 +COCCC(=O)NC(Cc1cccc(F)c1)c1cccc(F)c1 +CC(=O)c1cccc(S(=O)(=O)N2CCCC2C2CCCC2)c1 +CC(OCC1CC1)C(=O)NC1(c2ccc(Br)cc2)CC1 +N#CC(C(=O)c1ccc2nncn2c1)c1ccc(C(F)(F)F)cn1 +FC(F)(F)CSc1nc(CN2CCOCC2)nc2ccccc12 +CC(C)(C)C(=O)CNC(=O)c1cccc(-n2cccn2)n1 +COc1ccc(COC(=O)c2ccccc2S(C)(=O)=O)cc1F +CN(CC(=O)NC(C)(C)C)C(=O)NCc1cscn1 +Cc1ncoc1C(=O)NCc1cccnc1N(C)C1CCCCC1 +CC(C)C(C)NC(=O)Cn1nnn(-c2ccccc2Cl)c1=O +O=C(c1ccc(F)cc1F)N1CCN(Cc2n[nH]c(=O)[nH]2)CC1 +O=c1[nH]nc(-c2c(F)cc(F)cc2F)c2ccccc12 +Cc1nccn1-c1cc(CNC(=O)C(C)OCC(F)(F)F)ccn1 +O=C(CSc1nnc(-c2cccnc2)o1)NC1CCCC1 +Cc1cc(C)n(CCC(=O)N2C3CCC2CC(O)C3)c(=O)n1 +CCCn1cc(CNC(=O)c2ccc(-c3cc[nH]n3)cc2)cn1 +Cc1nc(C)c(CCC(=O)Nc2ccc(Cl)cc2)c(=O)[nH]1 +Cc1ccc(CNC(=O)Nc2ccc(F)c(F)c2F)n1C +Cc1ccccc1C(C)NC(=O)CSc1nncn1C(C)C +CC(C)CC(CO)NC(=O)Nc1cnn(-c2ccccc2F)c1 +CC(=O)NCC(=O)NC(CCc1ccccc1)c1ccccc1 +CCCn1nc(-c2ccc(OC)cc2OC)cc(CO)c1=O +CC(NC(=O)N(C)Cc1nccs1)c1nc2cc(Cl)ccc2[nH]1 +O=C(Nc1cccs1)N1CCCC(C(=O)N2CCCC2)C1 +COc1ccc(-n2nc(C)c(CO)c2C)cc1OC +Cc1c(CC2C(=O)N(C)c3ccccc32)oc2ccc(F)cc12 +CCCOc1cccc(-c2cc(C(N)=O)nc(N)n2)c1 +COc1cc(F)ccc1NCC1(O)CCCCC1 +COc1ccc2nc(NC(=O)c3cccc(N(C)C)c3)sc2c1 +CCc1nnc(CN(CC)C(=O)Nc2ccc3nn[nH]c3c2)o1 +C=CCOC(=O)c1nnc2nc(SC)nn2c1C +Cc1cc(N(C)C)c2nnc(C(=O)NC3CC3)n2n1 +COc1cc(F)ccc1NCc1cccc(C(=O)N2CCCCC2)c1 +CCOC(=O)c1c(NC(=O)Cn2cccn2)sc2c1CCC2 +Cc1csc(NC(=O)c2cccc(NC(=O)c3cccs3)c2)n1 +Cc1csc(C(=O)N2CCCC(c3nnc(C(F)(F)F)o3)C2)c1 +CCNc1nc(N2CCN(CCO)CC2)nc2c1C(=O)CCC2 +O=C(Nc1cccc(OCc2cccnc2)c1)c1ccn2nccc2c1 +Cc1ccn(Cc2cc(F)cc3cccnc23)c(=O)c1 +CC(C)c1nsc2c1c(Br)cn2C +CC(C)C(NC(=O)c1ccco1)C(=O)NCC1CCCO1 +Cc1cccc(OC(=O)COc2ccc(N3CCCC3=O)cc2)c1C +CCc1nc(CC(=O)Nc2ccc(SC)cc2)cs1 +CC(C)c1cccc2sc(NCCN3CCOCC3)nc12 +Cc1nnsc1C(=O)Nc1nnc(-c2cc(C)n(C)n2)o1 +CCc1cccc(NC(=O)NC(C)C(=O)N2CCCCC2)c1 +Cc1cc(C)c(C(=O)NC2CCN(c3ccccc3F)C2=O)c(=O)[nH]1 +CCN(CC)C(=O)c1nc(C(C)C)ncc1Cl +CCn1nc(C)c(C(C)NC(=O)c2cccc(-n3cnnc3)c2)c1C +O=C(c1cccc(Cn2cccn2)c1)N1CCOC2CCCCC21 +COc1ccc(C)cc1NC(=O)C(C)Oc1ccccc1N +COCC(=O)NC1(c2ccc(Cl)cc2)CCC1 +N#Cc1cc(C2NCCc3c(O)ccc(F)c32)ccc1F +Cc1cc(C(=O)NCCCn2c(C)nc3ccccc32)c(C)s1 +O=C(Cc1ccc(F)cc1)NCCn1ccc(-c2ccncc2)n1 +Cc1ccc(-n2c(C)nc3ncc(C)c-3c2N)cc1 +O=C(Nc1ccccc1C(=O)NC1CC1)c1cccc(-n2cccc2)c1 +CC(C)c1[nH]nc(C(=O)NCCNS(C)(=O)=O)c1N +N#CCC1CC=CC2c3cc4c(cc3C(=O)NC12)OCO4 +CC(=O)NCCC(=O)NCCc1cc(Cl)cc(Cl)c1 +CC(C)S(=O)(=O)NCc1ccc(Cn2cccn2)cc1 +COc1ccc(C2CC(=O)Nc3cc4c(cc32)OCCO4)cc1OC +COC(=O)c1[nH]c(C)c(C(=O)CN(C(=O)C2CC2)C(C)(C)C)c1C +COc1ccc(CCNC(=O)c2cc(C)ccc2O)cc1OC +N#Cc1cccc(NCc2nnc(-c3ccc(F)cc3)o2)c1 +CCOC(=O)c1cc(-c2ccc(OCC)cc2C)nn1C +CC(NC1C(=O)Nc2ccc(Br)cc21)c1ccccc1 +N#Cc1c(N)nc2c(c1-c1ccc(C(N)=O)cc1)CCc1[nH]ccc1-2 +COc1ccc(-c2csc(NC(=O)C3CCCO3)n2)cc1 +Cc1ccc(OCCc2nc(C(C)(C)O)cs2)cc1 +Cc1nnc(CNC(=O)CN(C)c2nc3c(F)cccc3s2)o1 +Cc1n[nH]c2ncc(C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)cc12 +CCS(=O)(=O)N1CC2CCCC(O)(c3cccnc3)C2C1 +Cc1cc(C)n(-c2ccc(NCCc3cccc(O)c3)nn2)n1 +COC(=O)c1c(C(=O)OC)c(C)n(Cc2cccnc2)c1C +Clc1cccc2ncn3nc(-c4ccsc4)nc3c12 +Cn1cnnc1CN(Cc1cccnc1)Cc1ccco1 +Cn1cc(C=c2[nH]c(=CCl)oc2=O)c2ccccc21 +Cc1nn2c(C#N)c(-c3ccc4c(c3)nc(C)n4C)nc2s1 +C=CCn1cnc2sc(C(=O)OCCOC)c(C)c2c1=O +Cc1c(C(=O)NC(C)c2ccncc2)[nH]c2c1C(=O)CCC2 +COc1ccc(-c2nn(Cc3ccncc3)c(=O)o2)c2ccccc12 +O=S(=O)(NCc1cccs1)c1ccc2c(c1)OCO2 +CC(c1ccncc1)N(C)C(=O)Cn1cnc2c(cnn2C)c1=O +COc1cccc(OC)c1-c1nc2c([nH]1)CC(C)(C)CNC2=O +CCN(C)c1ccc(C(=O)NCc2cccc(Cn3cccn3)c2)cc1 +COC(=O)c1ccc(C(=O)Nc2ncc(C)s2)cc1 +Cc1nc2c(c3c1COC(C)(C)C3)c(=O)ncn2Cc1ccccc1 +CCC(CO)NC(=O)Nc1cccnc1Oc1ccc(OC)cc1 +Cc1cc(C)n(CCNC(=O)C2CCCN2C(N)=O)n1 +CCCCCCNC(=O)CN1CC(C)OCC1C +COCCNC(=O)NCc1cc(OC)c(O)c(OC)c1 +COc1ccc(C(C)NC(=O)N(C)Cc2cc(C)on2)cc1OC +CC1CCCCC1NC(=O)CN(C)S(=O)(=O)c1ccccc1 +CN(C)c1nc(CNc2ccccc2C(=O)N2CCOCC2)ns1 +COc1ccc(-c2cc(C(=O)N(C)C)sc2C)cc1 +O=C(NCc1ccc(OC2CCCCC2)nc1)c1csnn1 +COc1ccc(CC(C)N(C)C(=O)c2sc3nccn3c2C)cc1 +Cc1ccc(Cc2cnc(NC(=O)CCc3nc[nH]n3)s2)cc1C +Cc1noc(C)c1C(C)C(=O)N1CCCC(c2ccn[nH]2)C1 +CC1CC1c1ccc(CN(C)Cc2nnc(C3CC3)o2)o1 +CCOC(=O)C1CCN(C(=O)CCn2ccnc2)CC1 +Cc1ccsc1C(=O)N(CC(=O)N(C)C)CC(F)(F)F +CCC(CC)(CO)NC(=O)c1ccc(Br)cn1 +COc1cc(CNC(=O)Nc2cccnc2)ccc1C +O=C(CCSc1ccccc1)Oc1cccc(N2CCCC2=O)c1 +Cn1ncc2ccc(NC(=O)c3cc(F)ccc3N)cc21 +O=C(NCc1ccnc(OC2CCC2)c1)C1CSc2ccccc21 +Cc1cccc(OCCCNC(=O)Nn2cnc3ccccc32)c1 +CC(C)n1nccc1NC(=O)c1cc(-c2cccs2)n[nH]1 +COc1ccccc1OCC(=O)Nc1ccc(SC(F)F)cc1 +COCCN1CCn2c(nc3cc(C(=O)NCC(C)C)ccc32)C1 +Cc1cccc(CCC(=O)N(CCO)CCO)c1 +Cn1ccnc1CNC(=O)c1cccc(N2CCCC2)c1 +CC(C)CC(C)OCCC(=O)N1CCOCC1C#N +Cc1cccc(C(=O)N(C)CCc2cnccn2)c1 +CSc1cc(C(=O)Nc2cc3c(cc2Cl)OCO3)ccn1 +O=C(OCc1csc(-c2ccccn2)n1)c1ccco1 +COc1ccccc1NC(=O)Cn1c(C)cc(C)c(C#N)c1=O +CC(C)(C)c1nnc(CNc2c(F)cccc2-n2cccn2)o1 +CCOc1ccccc1NC(=O)Cn1nc(-c2cccs2)oc1=O +O=C(c1ccccn1)N1CCc2onc(-c3ccc(Cl)cc3)c2C1 +CCOC(=O)c1cc(-c2cn[nH]c2)cc2c1NCC2 +Cc1cc(C)n(C2CCCN(C(=O)c3nc4nccc(C)n4n3)C2)n1 +COC(=O)C1CCN(C(=O)Cc2ccccc2C)CC1 +CC(C)(C)n1cc(C(=O)Nc2cccc(-n3cnnc3)c2)cn1 +CCc1nc(CNc2ccc(CC(N)=O)cc2)cs1 +Cc1cc(CN(C)Cc2cn(-c3ccc(F)c(Cl)c3)nn2)no1 +N#Cc1ccc(COC(=O)CN2C(=O)COc3ccccc32)cc1 +CCCCN(CC(N)=O)c1ncnc2c1CCCCC2 +CC(C)NC(=O)c1[nH]cnc1C(=O)N1CCCCCC1 +Nc1ccc(C(=O)NCCc2ccc(F)cc2)cn1 +C#CCn1cc(CN(C)C(=O)Nc2cnccc2C)cn1 +CCNC(=O)c1ccc(NC(=O)N(C)Cc2ccccn2)c(C)c1 +CC(=O)Nc1ccc(NC(=O)C2(c3cccc(Cl)c3)CCC2)cc1 +O=C(Cc1csc(-c2cccnc2)n1)N1CCOCC1 +CN(C)S(=O)(=O)c1ccc(OC(=O)c2cc3ccccc3o2)cc1 +CC(C#N)(NC(=O)CN1CC(c2ccccc2)OCC1(C)C)C1CC1 +CC1CCCN(C(=O)c2c(Cl)cccc2Cl)C1 +CC(c1ccccn1)N(C)S(=O)(=O)c1cccc(C(F)(F)F)c1 +CCOc1ccc(CN2C(=O)C(=O)c3cc(Cl)ccc32)cc1OC +Cc1ccc(C(CNc2ncccc2C#N)N2CCOCC2)o1 +CNC(=O)c1cnc(C=CC=Cc2ccccc2OC)s1 +O=C(c1ccc(Oc2ncnc3ccccc23)cc1)N1CCCC1 +O=C(NCc1cc(Cl)ccn1)Nc1cc(F)c(F)cc1F +CCOc1ccccc1NC(=O)C1CC(=O)Nc2nc(C)nn21 +CCc1nnc(NC(=O)NC2CCSc3ccc(F)cc32)s1 +O=C(NCc1ccc2c(c1)OCO2)N1CCN(c2nccs2)CC1 +COc1ccnc(NC(=O)c2sc(Cc3ccccc3)nc2C)c1 +COc1ccc(NC(=O)c2cccs2)cc1S(N)(=O)=O +CC(=O)Nc1ccc(N2CCOCC2)c2nonc12 +NC(=O)c1ccc(OCc2ccc(N)cc2Br)cc1 +Cc1nc2c(Nc3ccc4c(c3)OCCO4)ncnc2[nH]1 +Cc1ccc(Cl)c(OCC(=O)n2ccnc2)c1 +O=C(CCc1ccccc1O)NCCc1cccs1 +CN(CCc1ccccn1)C(=O)c1ccccc1F +O=C(Cn1ncc(Cl)c(Cl)c1=O)Nc1ccc(Cl)cc1 +Cc1cccc(-n2ncc(C(=O)Nc3nccs3)c2C)c1 +Cc1nc(C)c(CCNC(=O)Cc2cccc(OCC#N)c2)s1 +Cc1ccc(-n2ccnc2)c(C(=O)N2CCCC(C)C2)c1 +O=S(=O)(c1ccccc1C(F)(F)F)N1CCNCC1 +c1ccc2c(CN3CCOCC3C3CC3)csc2c1 +CCNC(=O)c1cccc(NC(=O)C(C)Oc2ccccc2C)c1 +COC1CCCCC1NS(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(-c2csc(NC(=O)C3CCCO3)n2)cc1F +Cc1noc(CCC(=O)NC(Cc2ccccc2)c2ccccc2)n1 +Cc1cccc(OCCN2CCC(N(C)Cc3nnc(C)n3C)C2)c1 +CN(C(=O)CCNC(=O)c1ccco1)c1cccc2ncccc12 +O=C(NC1CCCC1)c1cc(F)cc(Br)c1 +COc1ccc(CC(=O)N2CCC(N3CCNC3=O)CC2)cc1F +CC(C)(C)n1cc(C(=O)NCc2ccco2)c2cccnc21 +N#Cc1cccc(NC(=O)NC(CCO)c2ccccc2)c1 +Cc1ccc(Cc2nnc(-c3cc(N)ccc3F)o2)cc1 +N#Cc1ccc(C(=O)Nc2sccc2C#N)cc1 +CNC(=O)c1ccc(-c2ccc(OC)c(C(C)C)c2)nc1N +CC(NCC1COc2ccccc2O1)c1ccc(F)cn1 +CCOc1ccc(NC(=O)Cn2nc(N)cc2C)cc1 +CCCCc1nnc(NC(=O)NCCNC(C)=O)s1 +O=C1CCCN1CCCNC(=O)N1CCC(Oc2ccccc2)CC1 +CC1CCCC(OCC(=O)Nc2nc(-c3ccco3)cs2)C1 +CCn1c(C)cc(C(=O)COC(=O)c2cccnc2SC)c1C +O=C(NCCc1cccnc1)Nc1ccccc1F +Cc1ccc(C(=O)N=c2[nH]nc3cc(C)ccn23)c(C)c1 +CCCC(C)(C)NS(=O)(=O)c1cccc(S(C)(=O)=O)c1 +Cc1ccc(N(CC(=O)N2CCOCC2)S(C)(=O)=O)cc1Cl +Cc1noc(C)c1S(=O)(=O)N1CCN(C(C)C)CC1 +Cc1ccc(C(=O)NC(C)c2c(C)noc2C)cc1 +Cc1cnn(CC(C)Nc2nn3cc(C)nc3s2)c1 +CCOc1ccc(S(=O)(=O)NC(C2CC2)C2CC2)cc1 +Cc1cc(C(=O)N2CC(C(=O)NC(C)C)C3(CCOCC3)C2)c(C)o1 +CCn1nc(C)c(CNC(=O)Nc2cccc(C)c2C)c1C +CCN(CC)C(=O)c1cccc(NC(=O)c2ccc(C)cc2)c1 +CS(=O)(=O)N1CC(C(=O)N2CCCC2)Oc2ccc(Cl)cc21 +COC(=O)C1CCCCCC1NS(=O)(=O)Cc1ccccc1 +CCN(CCC(=O)OC)S(=O)(=O)c1c(F)cc(F)cc1F +Cc1ncsc1C(=O)Nc1cccc(OCC(=O)N(C)C)c1 +COc1cccc(C2CCCN2C(=O)c2ccnn2C(F)F)c1 +Cc1ccc(N2CCCS2(=O)=O)cc1NC(=O)CC(C)C +Cc1cccc(C(=O)Oc2cccc(NC(=O)c3ccco3)c2)n1 +Cc1nn(C)c(NC(=O)c2ccc(Cl)cc2)c1Br +CCOC(=O)N1CCN(C2OC(=O)c3ccccc32)CC1 +Cc1cc2occ(CC(=O)C(C#N)c3ccccn3)c2cc1C(C)C +Cc1noc(C)c1Cc1ccc(C(=O)Nc2ccn(C)n2)o1 +CNC(=O)C(CC(C)C)NC(=O)c1cccc(-c2n[nH]c(C)n2)c1 +Cc1cccc(C(=O)NC(C(=O)OC(C)c2cccnc2)C(C)C)c1 +CCCC(C)c1cn(CCc2ccc(S(N)(=O)=O)cc2)nn1 +CC(=O)Nc1cccc2c1ccn2CC(=O)Nc1ccccn1 +Cc1ccc(C)c(-n2nnnc2SC2CCOC2=O)c1 +Cc1ccc2nc(COC3CN(C(=O)c4ccno4)CC3F)[nH]c2c1 +CCCNC(=O)c1cccc(C(=O)NCC2Cc3ccccc3O2)c1 +Clc1ccc(OCCN2CCOCC2)c(Cl)c1 +O=C(NCc1ncc(-c2ccccc2)[nH]1)c1ccc(F)cc1F +Cc1nc2ccccc2n1CC(=O)NC(C)c1ccccc1 +Cc1scc(C(=O)NCCCN2CCOCC2)c1C +Cc1ncccc1CN1CCC(Oc2cccnc2)C1 +COCc1ccccc1NCC(=O)Nc1cc(Cl)ccc1C#N +CS(=O)(=O)c1cc(C(=O)Nc2cccc(O)c2)ccc1Cl +CCOc1cc(CN(C)C(C)CC#N)cc(Br)c1OC +COC(=O)C1CCN(C(=O)CSc2ncc3ccccn23)CC1 +CC(=O)c1cccc(S(=O)(=O)N2CCc3ccc(Cl)cc3C2)c1 +COCCN(C)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CCCC(C)NC(=O)c1ccc(OC)c(OC)c1 +COc1ccc(C2CCCCCN2Cc2nc(N)nc(N)n2)cc1 +O=C(CCNC(=O)NC(CO)c1ccccc1)NC1CCCC1 +COC(=O)c1ccc(-n2nc(C(N)=O)c3c2CCN(C)C3)cc1 +Cc1cn(-c2ccccc2)nc1NC(=O)c1scnc1C1CC1 +Cc1nc(C)c(C(=O)NCCCNS(C)(=O)=O)s1 +COC(=O)c1c(C)n(CCOc2ccccc2)c2ccc(O)cc12 +Cc1ccc(CNC(=O)Cc2cccc(C(F)(F)F)c2)n1C +CCOC(=O)C1CCN(C(=O)CN2CCOC(C)(C)C2)CC1 +CCN(CCO)C(=O)Nc1ccccc1Cc1ccccc1 +CC(C)C(C)(C#N)NC(=O)CN1CCN(C(=O)c2ccco2)CC1 +CCn1c(-c2cccc(OC(C)C)c2)ccc(C#N)c1=O +CCSc1ccc(NC(=O)Nc2ccccn2)cn1 +Cc1cc2cc(CN(CCC#N)Cc3ccccn3)oc2cc1C +Cn1c(=O)c2c(ncn2CCSc2ccccc2)n(C)c1=O +N#CCCCCC(=O)c1cccc(Br)c1 +CCOC(=O)c1nc(NCCN2CCOCC2)c2ccccc2n1 +CNC(=O)c1cccc(OC(=O)Cc2coc3cc(C)ccc23)c1 +COC(=O)c1c(C(=O)OC)c2ccccn2c1C(C)=O +CN(C)S(=O)(=O)NCCn1nc(C(F)(F)F)n(C)c1=O +COc1ccc(C(C)O)cc1NC(=O)c1cccs1 +CCOC(=O)c1c(C)oc2ncnc(N(C)CCO)c12 +CCn1nc(C)c(CNc2ncnc3c(C)nn(C)c23)c1C +Cc1nc(N2CC3CC(O)C(O)CC3C2)cc(-n2cccn2)n1 +CCOc1ccc(NC(=O)NCCc2ccccn2)cc1Cl +COCCCNC(=O)c1onc(-c2ccccc2C)c1N +CCc1nccn1S(=O)(=O)c1cc(Cl)c(C)cc1OC +CCn1nnc2c1CCN(C(=O)c1cscn1)C2COCC1CC1 +Cc1ccc(OCC(=O)NCc2noc(C)n2)cc1 +O=C(c1ccccn1)N1CC2CCC(C1)N(CC1CCC1)C2=O +COc1ccc(CNC(=O)CCC#N)cc1C(C)C +Cn1cc(C(N)=O)cc1C(=O)OC(c1ccccc1)c1ccccc1 +CC(C)CNC(=O)c1cccc(N(C)S(C)(=O)=O)c1 +CC(C)=CCC1(CO)CCCN(c2cccnn2)C1 +CC(NC(=O)c1sc2cccc(F)c2c1Cl)c1cnn(C)c1 +Cc1cc(NC(=O)c2sccc2NS(C)(=O)=O)n(C)n1 +O=C(c1ccncc1)N1CCCC1c1nc2ccccc2s1 +CC(C)C(NC(=O)c1ccccc1F)C(=O)NCCCO +CCC(C)C(C)NC(=O)NCCNC(=O)c1ccccc1O +COCCN(Cc1cnn(C)c1)C(=O)c1cccc(-c2cn[nH]c2)c1 +CC(=O)N(C)c1ccccc1NCc1csc(C)n1 +C#CCN1CCN(CC(=O)Nc2cc(C)no2)CC1 +Nc1cccc(CNS(=O)(=O)Cc2ccc(F)c(Cl)c2)c1 +CCOC(=O)c1[nH]c(C)c(C(=O)NC(C)CC)c1C +Cc1ccc(NC(=O)Cn2c(C)cc(C)c(C(N)=O)c2=O)c(C)c1 +Cc1cccc(C(=O)OCC(=O)N(C)Cc2ccccc2)c1O +COc1ncccc1NC(=O)c1n[nH]c2ccccc12 +CC(C)Cc1nnc(NC(=O)c2cccnc2N)s1 +Cc1ccc(NC(=O)NCCc2ccccn2)cc1OCC(F)F +O=C(c1ccncc1Cl)N1CCOc2ccc(F)cc21 +CC(=O)c1ccc(NC(=O)CCc2nc(-c3ccco3)no2)cc1 +COCc1cccc(C(=O)Nc2c(C)cc(Br)cc2C)c1 +CCC(=O)NC(C)Cc1ccc(Br)cc1 +O=C(COc1cccc(-n2cnnn2)c1)Nc1ccc2ccccc2c1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(C(=O)NC)c(Cl)c1 +CCCC(=O)N1CCC(S(=O)(=O)c2nncn2C)CC1 +COC(=O)N(C)c1ccc(OCc2ccccc2C#N)cc1 +COc1ccc(C(=O)NCc2coc(-c3cccs3)n2)c(O)c1 +CCN(CC(C)C)C(=O)Nc1ccc2c(c1)OCCO2 +NC(=O)C1CCCN(C(=O)c2ccc(OCC(F)(F)F)nc2)C1 +O=C1COc2cc(C(=O)NCC(O)c3ccc(Cl)cc3)ccc2N1 +Cc1sc(=O)n(CC(=O)c2cc(F)ccc2F)c1C +CCN(Cc1ccccc1)C(=O)c1cccc(OC)c1F +O=C(N1CCC2(CC1)OCCCC2O)C1(c2ccc(Cl)cc2)CC1 +Cc1ccc(O)c2c1C(CNC(=O)c1ccccc1)NCC2 +O=C(CN1CNc2scc(-c3ccccc3)c2C1=O)C1=NC=CC1 +N#Cc1nc2ccc(F)c(F)c2n1CC(F)(F)F +COc1ccc(NC(=O)c2scnc2C2CC2)cn1 +C#CCCN1CCN(C(=O)c2ccc3c(c2)NC(=O)CO3)CC1 +CC(OC(=O)c1cc2ccccc2cc1O)C(N)=O +CNS(=O)(=O)c1ccccc1N1CCN(C(=O)c2ccoc2)CC1 +CCC(NCC1CCCO1)C(=O)c1ccc(OC)c(N)c1 +CC(=O)Nc1ccc(C(=O)NCc2ccccc2Cn2ccnc2)cc1 +CC(=O)Nc1ccc(NC(=O)Nc2ccc(C(C)=O)c(C)c2)cc1 +CCC(Sc1nc(C)cc(N)n1)C(=O)Nc1ccc(F)cc1 +CC1CCCCC1NC(=O)CC(O)(c1nccn1C)C(F)(F)F +CCn1nc(C)cc1C(=O)N1CCOC2CCC1C2OC +COc1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1 +O=C1NC2(CCOCC2)Nc2c1sc1ccccc21 +Cc1ccc(CC(=O)NCC2CN3CCCCC3CO2)s1 +COCCNc1nc(-c2cc3c(n(C)c2=O)CCC3)cs1 +C=CCN1CC2(CCN(c3ccc(C)nn3)CC2)OCC1=O +Cc1ccc2c(CNc3cccc(C)c3C(N)=O)cc(=O)oc2c1 +Cc1ccc(C(=O)Nc2nc(-c3ccc(F)cc3)cs2)cn1 +COc1ccc(-n2cnnc2SCC(=O)OC2CCCCC2)cc1 +Cc1nnc(-c2ccccc2C(=O)Nc2cccc(C(F)(F)F)c2)o1 +COC(=O)c1cc(-c2ccc(S(C)(=O)=O)cc2)nn1C +O=C(c1cccnc1)N1CCN(C(c2ccccc2)C(F)(F)F)CC1 +C#CCN1CCN(Cc2cc3ccccc3[nH]c2=O)CC1 +COC(=O)C1=C(CN2CCOCC2)NC(=O)NC1c1ccccc1C +Cc1ccc(CN2CCOCC2)cc1Br +COc1ccc(CCNC(=O)c2cc(C3CC3)[nH]n2)cc1 +O=C(Nc1cnc(C2CC2)nc1)N1CCc2ccccc2C1CO +CC12CCC3C(CCC45CC(=O)CCC34C5)C1CCC2=O +Cc1ccc(NC(=O)Cn2cnnc2C#N)cc1C +c1ccc2c(OCc3nc(C4CC4)no3)cccc2c1 +N#Cc1ccccc1OCc1ccc(C(=O)Nc2cc[nH]n2)o1 +Cc1cc(O)c2c(c1)C(CNC(=O)OC(C)(C)C)NCC2 +Cc1cccc(OCC(O)CNC(=O)NCc2cccc(C#N)c2)c1 +COCCNc1ccc2nnc(C(F)(F)F)n2n1 +COC(=O)c1c(C)nn(-c2ccc(OC(F)(F)F)cc2)c1C +O=C(NCc1nc2cccnc2n1Cc1ccccc1)C1CC1 +CC(=O)NC(C(=O)N(C)c1nc(C)cs1)C(C)C +Cc1nc(-c2ccc(S(=O)(=O)NCc3ccccc3)cc2)co1 +COc1ccc(F)cc1NC(=O)NCc1nc(C2CC2)cs1 +Cc1ccc(C(=O)Nc2cnc3c(c2)c(=O)n(C)c(=O)n3C)s1 +CCSc1ccc(NC(=O)c2cc(F)cc(F)c2)cn1 +COc1ccc(CC(=O)NCC(=O)C(C)(C)C)cc1 +CCOC(=O)N(C)CCc1cc2c(cc1C)OCO2 +COc1ccc(N)cc1-c1nnc(NC(=O)C(C)(C)C)s1 +Cc1ccc(C(=O)NCCNC(=O)NCc2ncn(C)n2)cc1F +O=C(Nc1ccc2c(c1)COC2=O)c1cccc(F)c1 +COCC(=O)NCCOc1cccc(C(C)(C)C)c1 +O=C(Cc1ccsc1)N1CCCC(c2n[nH]c3nccnc23)C1 +Cc1cc(SCC(=O)N2CCC(O)C2)c(C)cc1Br +COc1ccc(C(=O)Nc2nc(SC)ns2)cc1 +Cc1csc(C(C#N)C(=O)C2CC2c2ccco2)n1 +COc1ccc(OC(C)C(=O)Nc2ccc(C)c(NC(C)=O)c2)cc1 +O=C(NCc1ccc(Cn2ccnc2)cc1)c1cc2ccccc2s1 +C=CCNc1ncnc(Nc2ccc(C(C)=O)cc2)c1N +C#CCOC1C(CO)OC(n2ccc(N)nc2=O)C1O +CC(C)COC1CCN(C(=O)CC(C)c2ccc(F)cc2)CC1 +COC(=O)c1sc2ncccc2c1-n1c(C)ccc1C +O=C(NC1CCCCCC1)C1CCN(C(=O)NC2CC2)CC1 +c1cc2ccc(NCc3csc(N4CCCC4)n3)nc2[nH]1 +COCCN1CCN(C(=O)NCc2nc(C)c(C)o2)CC1=O +CCn1nc(C)cc1C(=O)NCC(=O)N(C)Cc1ccc(F)cc1 +COCCNC(=O)CCNc1ccc(Cl)cc1C#N +COc1cc(OC)cc(C(=O)N2CCOC(=O)C2(C)C)c1 +CCc1ccccc1OCC(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +CCCC(=O)NCCS(=O)(=O)N1CCNCC1 +COc1ccccc1-c1noc(C(C)NC(=O)N(C)C(C)C)n1 +COC(=O)c1nnn(CC(=O)Nc2ccc3c(c2)OCO3)c1N +c1cc2c(cc1CNc1nnc(CC3CC3)o1)CCO2 +O=C(Nc1ccc2c(c1)COC2)N1CCCCCC1 +Cc1ccc(-n2nnnc2NCCNC(=O)c2cccnc2)cc1 +CCN(C(=O)CNc1cccc(C#N)c1)c1ccccc1 +CCn1nc(C)cc1C(=O)N1CCC2CC(C)OC2C1 +O=C(CN1CCOCC1C1CC1)Nc1ccc(F)cc1F +CCCOc1c(Cl)cccc1NC(=O)NCc1c(C)n[nH]c1C +O=C1CNCC(C(=O)NCCCc2ccccc2)N1 +CCCNc1c(C(=O)OCC)c(=O)[nH]c2cc(Cl)ccc12 +Cc1ccc(C#N)cc1NC(=O)C1(C)CC1(Cl)Cl +COCc1cncc2c1CCN(Cc1ccccn1)C2 +Cc1cc(S(=O)(=O)NCc2ncn(C)n2)ccc1F +Cn1ncc2c(NCc3ccc(CS(N)(=O)=O)cc3)ncnc21 +CNc1snc(C)c1C(=O)NC1CCCCCC1 +CCN1CCOC(C(=O)N(CC)Cc2cccc(F)c2)C1 +COC(=O)C(C)S(=O)(=O)N(C)c1cccc(N)c1 +O=C(NCc1ccc2c(c1)OCO2)c1cccc(OCC(F)F)n1 +O=C(c1cnccn1)N1CCNC(Cc2ccccc2)C1 +CCCC(=O)NCC(=O)Nc1cc(C#N)ccc1C +O=C(NCc1ccc(-c2ccsc2)cc1)c1ccc2ncnn2c1 +Cc1cccc(OCC(O)CN2CCOC(c3nccs3)C2)c1 +COCC(=O)NC1(c2ccc(Br)cc2)CCC1 +Cc1ccc(NC(=O)CCC(C#N)c2ccccn2)cc1 +Cc1cc(C)cc(CCNC(=O)c2cscn2)c1 +COCCn1cc(CCNC(=O)c2ccc(C)cc2)c2cccnc21 +CC1CCN(C(=O)Cc2cn3ccsc3n2)C(C)C1 +O=C(CCN1CCOC1=O)Nc1ccc(Cl)c(Cl)c1 +COCCOc1cccc(NC(=O)N2CCC(n3cccc3)CC2)c1 +COC(=O)CCSc1nnc(-c2ccc(Cl)cc2)n1C +COC(=O)C(C)Sc1ncc(-c2ccccc2)n1C +Cc1ccc(F)cc1S(=O)(=O)NC(C)(C)CO +CC(C)(C)OC(=O)NCc1ccnc(C(F)(F)F)c1 +CCc1nnc(NC(=O)CS(=O)(=O)NC2CCC(C)CC2)s1 +Cc1nc(SC2CCN(c3ccccc3F)C2=O)oc1C +CC(=O)NCC1CCN(C(=O)c2cc3ccccc3s2)CC1 +CCS(=O)(=O)NCCS(=O)(=O)N1CCC2CCCCC21 +Cc1cc(C)nc(C2CCN(C(=O)c3cnccn3)C2)n1 +COc1ccc(F)cc1NC(=O)N1CCCC(Cc2noc(C)n2)C1 +CN(C)C(=O)c1cccc(NC(=O)N(C)CC2CCCCC2)c1 +COC1CCCOC12CCN(S(=O)(=O)c1cn(C)cn1)CC2 +Cc1ccc2oc(C(=O)Nc3ccc(S(N)(=O)=O)cc3)cc2n1 +CCCN(C(=O)C(C)n1cncn1)c1cccc2ccccc12 +Cc1ccc(C(=O)N2CCN(c3ccccc3C)CC2)s1 +O=C(Nc1c(F)c(F)c(F)c(F)c1F)c1ccncc1 +Cc1nnc(SCC(=O)N(C(C)C)C(C)C)n1N +Cc1ccc(NC(=O)C(C)n2ncc(-c3ccccc3)nc2=O)c(C)c1 +CC(C(=O)N(C)CCc1cccc2ccccc12)n1ccnc1 +Cc1ccc(C(C)NC(=O)NCc2cccc(N(C)C)c2)o1 +COC(C)C(=O)Nc1nc(-c2ccc3c(c2)OCCO3)cs1 +Cc1cc(NC(=O)c2cc(C)n(-c3ccccc3Cl)n2)c[nH]c1=O +CCc1cc(C(=O)N2CCC(c3cc4cccnc4[nH]3)CC2)on1 +Cc1ccc(C(=O)OCCNC(=O)c2ccncc2)c(C)c1 +COc1ccccc1S(=O)Cc1c(C)cc(C)c(C(C)=O)c1C +CCNC(=O)c1cccc(NC(=O)CNc2cc(C)ccc2C)c1 +CCn1cnnc1CNC(=O)CCc1ccccc1 +Cc1cccc(OCC(=O)N(Cc2ccco2)CC2CCCO2)c1 +CC(NC(=O)c1ccc[nH]1)c1nc(-c2cccnc2)cs1 +COC(=O)CNC(=O)c1cn(-c2ccc(C)cc2)nc1-c1ccccc1 +Cc1nc2c(c(C)nn2C)c(C)c1CCC(=O)Nc1ccn(C)n1 +CC(C)C(C(=O)N1CCN(Cc2cscn2)CC1)n1cncn1 +Cc1ccnc2nc(C(=O)OC3CCCCCC3)nn12 +CC(Sc1nncn1C)C(=O)NC(C)c1ccc2c(c1)CCCC2 +Cc1ccccc1C(=O)N1CCc2ccc(O)cc2C1 +O=C(NC(CC(F)(F)F)c1ccc(F)cc1)c1ccoc1 +COc1nn(C)cc1C(=O)NCc1cc(-c2ccc(F)cc2)on1 +O=C(c1ccco1)n1nc(-c2ccco2)nc1NCc1cccs1 +O=C(C1CC=CC1)N1CCC2OCCCC2(COCC2CC2)C1 +O=C(C1CCC1)N1CCCC1c1nnc2ccccn12 +CCCc1n[nH]c(C2CN(C(=O)C(C)N3CCCCC3=O)CCO2)n1 +O=C(NC1CCCC1)c1cc(-c2cccnc2)n(-c2ccccc2)n1 +Cn1cc(C(=O)NCC(=O)Nc2ccc(Br)cc2)cn1 +CC(Cc1ccco1)NC(=O)c1ccc(-c2noc(C3CC3)n2)cc1 +CCCCS(=O)(=O)c1nsc(C(=O)NC)c1N +CCCS(=O)(=O)N(CCCO)c1ccccc1F +COc1ccc(C(=O)Nc2ccc(OC)c(OC)c2)c(OC)c1 +CCCCOc1nc(C)nc(NC2CCCCC2)c1N +CC(C)(C)C(=O)N1CCC(Cn2c(-c3ccccn3)noc2=O)CC1 +COc1ncccc1CN(C)C(=O)Cc1ccccc1F +COc1nc(C(C)(C)C)nc(NCCc2ccccc2)c1N +O=C(NCc1cn2ccsc2n1)c1cc(F)cc(F)c1 +COc1ccc(NC(=O)c2cnc(N3CCCC3)nc2)c(OC)c1 +Cc1cccn(CC(=O)N(Cc2ccco2)CC(F)(F)F)c1=O +CCCCN(C)C(=O)NC1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +CCc1ncncc1C(=O)N1CCCC(n2nc(C)nc2C)C1 +CCOC(=O)c1ncn(C(C(=O)OC)C(C)C)c1N +CC(=O)N1CCC(NC(=O)CCc2ccccc2F)CC1 +CC(C)n1[nH]c(=O)c2c1N=C(O)CC21C(=O)N(C)c2ccccc21 +CC(=O)Nc1ccc(OCC(=O)Nc2c(C)cccc2C)cc1 +COCC1CCCN(C(=O)c2cn(CCC3CCCCC3)nn2)C1 +COC(=O)CCS(=O)(=O)Nc1ccccc1N +Cn1cccc1C1COCCN1C(=O)c1csc2ccccc12 +CC(=O)Nc1cccc(NC(=O)COc2cccc(CO)c2)c1 +CCCCNC(=O)c1c(-c2ccc(F)cc2F)noc1C +CCCOc1ccc(C(=O)Nc2ccc(C(=O)NCC)cc2)cc1 +COCC(NC(=O)C1CC1c1cccc(F)c1F)C(N)=O +CS(=O)c1ccc(CN2CCC(Oc3cccc(Cl)c3)C2)cc1 +CC(=O)NCCNC(=O)N1CCCN(C(=O)c2cccc(C)c2)CC1 +O=C1OCCC1N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 +O=C(Nc1cc(F)cc(F)c1)c1cccc2[nH]ccc12 +CSc1sc(NC(=O)c2ccc(C)c(NC(C)=O)c2)nc1C +O=C(NCc1ccncc1)c1cc2cc(F)ccc2[nH]1 +Cc1cc(=O)[nH]c(C2CCCN(C(=O)c3cscn3)C2)n1 +CCC(C)N(Cc1csc(C)n1)Cc1nc2ccccc2c(=O)[nH]1 +Cc1ccc(NC(=O)CNC(=O)OC(C)(C)C)cc1C +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)Nc1cc(C)on1)O2 +CCc1ccccc1NCC(=O)Nc1cccc(N2CCCC2=O)c1 +c1cc(CNc2ccc(-c3csnn3)cc2)cs1 +C#CCN(Cc1ccc(F)cc1)C(=O)NC(C)c1ccncc1 +CCS(=O)(=O)N(C)C(C#N)c1ccc(C(C)(C)C)cc1 +Cc1cccc(NC(=O)c2ccc3c(c2)CCCN3S(C)(=O)=O)c1 +Cc1nn2cccnc2c1C(=O)OCCN(C)c1ccccc1 +O=S(=O)(NC1CCCC1)c1ccc(F)c(F)c1F +COc1ccccc1C(=O)N1CCN(C(=O)C(C)C)CC1 +CCCc1nnc(N2CCC3(CCOCC3)CC2)o1 +CC(C)(C)CC(=O)NCC(=O)OCC1CCCCO1 +CCC(CC1CCCC1)C(=O)NCC(C)N1CCOCC1 +Cc1nc(C2CCN(C(=O)C(C)c3cccs3)CC2)no1 +Cc1cc(NC(=O)CCCNC(=O)c2ccc(Cl)cc2)ccn1 +Cc1nc(CN2CCN(C(=O)c3ccccn3)CC2)no1 +Cc1ccc(NC(=O)CCC(O)c2cccs2)c(C)c1 +Cn1c(C(N)c2ccccc2)nc2ccccc2c1=O +Cc1noc(C)c1N(C)C(=O)Nc1ccc2c(c1)COC2 +Cc1nc2ncccc2c(=O)n1CCNS(=O)(=O)c1ccccc1 +CC(CN1CCN(c2ccccc2)CC1)NC(=O)N1CCCC(O)C1 +Cc1nnc(NC(=O)c2cnc(C(C)(C)C)nc2N)s1 +O=C(Nc1ccccc1)Nc1cccc(NC(=O)C2(O)CCCC2)c1 +COc1cccc2cc(C(=O)Nc3ccc(O)cc3)c(=O)oc12 +CC(=O)Nc1ccc(OC(=O)c2cc(Br)c[nH]2)cc1 +CC(=O)NCc1cc(=O)[nH]c(CC(c2ccccc2)c2ccccc2)n1 +COc1ccc(O)c(C2=NCCNC(C(F)F)=C2)c1 +Cc1noc(C)c1CN(C)C(=O)C1CC(=O)N(C2CCCCCC2)C1 +Cc1ccc(NC2C(=O)Nc3ccc(F)cc32)c(C)c1 +COc1cccc(C#CCOC(=O)C2CC3CCC2O3)c1 +COc1ccc(C2CCCN2C(=O)CC2C=CCC2)cc1OC +COC(=O)C(C)Sc1ncnc2c1nnn2-c1ccc(F)cc1 +CCc1ccccc1OCC(=O)N(C)Cc1cccc(C#N)c1 +O=C(COc1nnc(-c2ccccc2)o1)NC1CCCCCC1 +Cc1cc(=O)oc(C)c1C(=O)Nc1ccc(-n2cnnn2)cc1 +CCC1C(=O)NCCN1C(=O)Cc1ccc(F)c(F)c1 +Cc1ccoc1C(=O)NCCCNC(=O)Cc1cccc(F)c1 +COCCNC(=O)c1cc2sc(C)cc2n1Cc1cccc(F)c1 +CCN(C(=O)c1csc(NC(C)=O)n1)C1CC1 +N#Cc1ccc2nc(C(=O)NCC(F)(F)F)sc2c1 +CC(C)(C)NC(=O)CNC(=O)NCc1cc(Br)cs1 +O=C(Nc1ccon1)c1cc2sccc2n1Cc1ccccc1F +CCOc1ccccc1NC(=O)c1cccc(C(=O)OC)n1 +O=C(c1ccccn1)N1CCC(c2ccsc2)CC1 +CCC(CC)NC(=O)NCc1ccc(Cn2ccnc2)cc1 +CCNC(=O)CN(CC)C(=O)c1c(C)[nH]c2ccccc12 +CC(=O)Nc1nc(C(=O)Nc2ccc(C)c(-n3cnnn3)c2)cs1 +CCCC(C)(CO)NC(=O)NC(C)c1ccc(-c2cncnc2)cc1 +Nc1ccc(=O)n(CC(=O)N2CCNC(=O)CC2)c1 +c1ccc(-n2nnnc2NCC2CCCOC2)cc1 +CCN(CC)C(=O)c1sc(NC(=O)OC)c(C(=O)OC)c1C +O=c1n2c(c(-c3ccccc3)n1-c1ccc(F)cc1)CNCC2 +Cc1cc(=O)n(C)cc1NC(=O)c1cccc(Cl)c1Cl +Cc1ccccc1C(=O)OCC(=O)N1CCOCC1 +NC(=O)c1ccc(Cl)cc1NC(=O)Cc1ccc(F)cc1F +COc1ccc2c(c1)N(CC(=O)NC1CCC(C)CC1)CCO2 +CNS(=O)(=O)c1ccccc1NCc1cccnc1 +CCc1ccc(OC)c(S(=O)(=O)NCc2ccco2)c1 +CCCCN(CC#Cc1ccccc1)C(=O)c1cccc(=O)[nH]1 +CC(=O)NCCn1ccnc1-c1cc2ccccc2o1 +CCn1cc(C(=O)Nc2ccccc2SCC(N)=O)cn1 +CNC(=O)c1ccc(Cl)c(NC(=O)c2ccc(C)nc2)c1 +COc1cc(C(N)C(=O)NC2CC2)c(OC)cc1C +C=CCNC(=O)NCCN1c2ccccc2CC1C +Fc1cccnc1OCC12CCOC1CCN(Cc1nccs1)C2 +CCOC(=O)C1(NC(=O)c2[nH]nc(C)c2Br)CCCC1 +CC(NC(=O)c1cccs1)C(=O)Nc1cc(C(C)(C)C)n[nH]1 +O=C(c1cncc(-c2cccc3cccnc23)n1)N1CCCCC1 +Cc1ccc(OCCCNC(=O)N(C)Cc2c(C)noc2C)cc1 +Cc1noc(-c2nn(C)c3c2CN(C(=O)c2cccs2)CC3)n1 +CS(=O)c1ccc(CNCC2CC(=O)Nc3ccccc32)cc1 +Cc1ccccc1-n1nccc1NC(=O)NCCCc1cnn(C)c1 +CC(C)c1cc(OC2CC2)c[nH]c1=NS(C)(=O)=O +Cc1ccc(NC(=O)N2CCC(C(=O)NCc3ccco3)CC2)cc1 +CCOc1ccc(CC(=O)NCC(=O)NC2CC2)cc1 +Cc1ccc(CC2Oc3ccc(O)cc3N(C)C2=O)cc1C +CC(=O)Nc1ccc(C(=O)N(C)C(C)c2ccccc2F)cc1 +Cc1cnc(NC(=O)CCCn2cnc3ccccc3c2=O)s1 +Cn1cc(S(=O)(=O)N2CCC(O)CC2)c(N)n1 +O=C(Nc1ccccc1)N1CCSc2ncccc21 +COC(=O)C1=C(C)C(C(=O)Nc2ccc(SC)cc2)=NC1C +CCC(C)Cn1c(CNC(=O)c2ccco2)nc2ccccc21 +CC(C)Cc1nc(CNC(=O)CC2CCCC2)no1 +COc1ccc(C(=O)NCCc2ccccn2)cc1N +CC(C)CNC(=O)c1c[nH]nc1-c1ccccc1Cl +CC(=O)NC(C)C(=O)NCc1ccc(N2CCCCC2=O)cc1 +COc1cc(COC(=O)C(C)n2nc(C)cc2C)ccc1C +Cc1ccc(NC(=O)CSc2nnnn2C)c(Cl)c1 +CCOc1cc(C(=O)N2CCN(c3nccs3)CC2)ccc1OC +CCC1CCCCN1C(=O)NCC(C(C)C)N1CCOCC1 +c1ccc(CCNCc2nc3ccccc3s2)nc1 +CCNC(=O)C1CN(c2nc(-c3ccc(C)cc3)no2)C1 +COc1cccc(C(=O)NC(C)c2nc(-c3ccc(F)cc3)no2)c1 +c1ccc(-c2cc(CN(Cc3cccnc3)CC3CCCO3)n[nH]2)cc1 +Nc1ccc2c(c1)OCC(=O)N2CCCOc1ccc(Cl)cc1 +Cc1cccc(NC(=O)c2cnc3c(cnn3C(C)C)c2)n1 +CCCCCC(C)NC(=O)Nc1ccc(C(N)=O)cc1 +CCc1nnc(NC(=O)N2CCN(c3cccc(C)c3)CC2)s1 +CCOc1ncccc1CNC(=O)c1ccc(O)c(Cl)c1 +COc1ccc(C(O)C(=O)Nc2cc(C)ccc2OC)cc1 +Cc1ccc(-c2nnc(NC(=O)c3ccnn3C(C)C)o2)c(C)c1 +CC(C)Oc1ccc(S(=O)(=O)N2CCCCC2)cn1 +O=C1CCc2cc(OCC(=O)N(CC3CCOC3)C3CC3)ccc2N1 +CC(=O)c1ccc(NC(=O)COC(=O)c2ccccc2F)cc1 +Cc1ccc(C)c(C(O)CNC(=O)CCc2ccccc2)c1 +Cc1ccc2oc(=O)c(CC(=O)c3sc(C)nc3C)nc2c1 +COC(=O)CNC(=O)c1cccc(OCc2cccc(C)c2)c1 +CCC(COC)NC(=O)c1cc(Br)ccc1F +Cc1csc(=O)n1CCSc1nnnn1-c1ccc(O)cc1 +CCc1ncc2c(n1)CN(C(=O)c1cnc3ccccn13)C2 +COc1cc2c(cc1O)CCNC2C(CO)c1ccccc1 +CC(CCCO)NC(=O)NC1CC(=O)N(CC(F)(F)F)C1 +COC(=O)c1cc(CCc2ccccc2)nn1-c1ccccn1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccccn1 +NC(=O)c1ccc(C(=O)N(CC(F)F)c2cccc(Cl)c2)s1 +O=C(Nc1nnc(C2CC2)s1)c1ccc(Cl)cc1Cl +CC(CNC(=O)N1CC(=O)NC2CCCCC21)Cn1cccn1 +c1cncc(-c2n[nH]cc2CN2CCOC(c3nccs3)C2)c1 +CC(O)(CNC(=O)C1CC1)c1ccc(F)cc1F +COc1cccc(-c2cc(C(=O)NCc3ccccn3)n(C)n2)c1 +Cc1cnn(CCC(=O)NCC(=O)Nc2c(C)cccc2C)c1 +COc1ccc(-c2cc(=O)n(CC(=O)Nc3ccccn3)cn2)cc1 +Fc1cc(Cl)c2c(c1)C(c1ccco1)NCC2 +CCn1c(SCC(N)=O)nnc1C1(C)COc2ccccc2O1 +CCc1ccc(-c2c(C)cn(C)c(=O)c2C#N)cc1 +Cc1ccnn1CC(=O)N1CCC2(CCC(=O)N(CCCO)C2)CC1 +CC(C)(C)NS(=O)(=O)c1cc2c(cc1Cl)NC(=O)CO2 +CCc1cnc(N2CCOC3(CCCN(c4cnccn4)C3)C2)nc1 +COc1cccc(-c2cn3ccn(-c4ccc(F)cc4)c(=O)c3n2)c1 +CCCCc1nc(COc2cccc(-c3nnco3)c2)no1 +CN(Cc1cccc(C(N)=O)c1)C(=O)C1CC=CCC1 +COCCCNS(=O)(=O)c1c(C)nn(C)c1N +Cc1nc(-c2ccc(NC(=O)c3ccc(F)cc3)cc2)cs1 +CCOc1cc(NC(=O)c2cncn2-c2ccccc2)ccc1OC +O=C(NCCCn1cncn1)c1cncc(Br)c1 +C#CCN1CCC(C(=O)NC2CCCC(C(F)(F)F)C2)CC1 +Cc1ccc(C(N)=O)cc1OC(=O)Cc1cccc(OCC#N)c1 +CC1(NC(=O)Nc2ccc3c(c2)OCC(=O)N3)Cc2ccccc2C1 +Cc1ncc(-c2cc(=O)[nH]c(NCc3ccccn3)n2)c(C)n1 +COc1c(C)cc(-c2nn3cc(N)nc3s2)c(C)c1C +CCc1ccccc1OC1CN(C(=O)COCC2CCCO2)C1 +CC(=O)c1nc(-c2ccc(Br)cc2)[nH]c1C +Fc1ccc(Oc2ccnc(NCc3ccncc3)n2)cc1 +COCCN1C(C)CN(Cc2sc(N(C)C)nc2C)CC1C +CCc1cccc(NC(=O)NCC(=O)Nc2c(C)cccc2C)c1 +COCCNC(=O)CC1Nc2ccccc2NC1=O +COc1ccc(NC(=O)CC(c2ccco2)n2cccc2)cc1OC +COC(=O)CCn1c(=O)[nH]c2ccc(F)c(F)c21 +Cc1nnnn1-c1cccc(C(=O)NCc2ccc3c(c2)OCO3)c1 +CCC1(CNC(=O)Nc2ccccc2CN2CCNC2=O)CC1 +COc1ccc(NC(=O)NC(C)(C)CO)cc1C +Cc1ccc(=O)n(CC(=O)NCC2CCCO2)n1 +CCNC(=O)CN(CC)C(CC#N)c1ccccc1 +CCCNC(=O)C1CCN(c2cc(Cl)ccc2Cl)C1=O +CCOC1CCCN(S(=O)(=O)c2cc(F)ccc2F)C1 +CCOC(=O)CCCNC(=O)Nc1ccc(F)cc1Br +COc1cccc(NCc2cc(OC)c3c(c2)OCCO3)c1 +COc1cccc(OCCC(=O)C2CCCCC2)c1OC +COc1ccccc1C(=O)COC(=O)c1ccc(-n2cnnn2)cc1 +CC(C(N)=O)S(=O)(=O)c1ccccc1Br +Cc1ncsc1CCOC(=O)c1ccc(Cn2ccccc2=O)o1 +O=C(CC1CCCC1)Nc1ccc2c(c1)OCC(=O)N2 +CCNC(=O)Nc1ccccc1S(=O)(=O)N1CCCCC1 +O=C(OCc1ccnc(-n2ccnc2)c1)c1cccc(-n2cccn2)n1 +CNc1ncnc(Nc2ccc(Cl)cc2C)c1N +COc1ccccc1C(=O)NC1CCCN(Cc2ccccc2)C1=O +CCOc1ccc(-c2cc(C(=O)OC)nc(=O)[nH]2)cc1OC +COCCCC(=O)Oc1cccc(N2CCCC2=O)c1 +CCC(C(=O)N1CCC(Oc2ccc(C#N)cn2)CC1)c1ccccc1 +CCOc1ccc(NC(=O)N2CCN(c3ccc(C)nn3)CC2)cc1 +Cc1cccc(NC(=O)c2ccc(NC(N)=O)cc2)c1C +Cc1c(C(=O)N(C)C2(C#N)CCC2)nnn1-c1cccc(Cl)c1 +Cc1ccc(C(=O)NCCc2ccc3c(c2)OCCO3)cc1F +Cc1cc(C)n2nc(C)c(C(=O)N3CCCC3)c2n1 +CC(NC(=O)CCc1ccccn1)c1ccccn1 +Cc1ccc(-n2cnnc2SCC(=O)NC2CCOCC2)c(C)c1 +CCOc1ccccc1C(=O)Nc1ccc2c(c1)CN(C(C)=O)CC2 +CC(C)C(CO)NC(=O)NCc1ccnc(OC(C)(C)C)c1 +c1ccc(OC2CCC3C2OCCN3Cc2ccoc2)nc1 +COc1cc2ncnc(Nc3cc(C)ccc3O)c2cc1OC +Cc1nc(C(=O)Nc2cc(Cl)ccc2N2CCCC2=O)c(C)s1 +CC(=O)Nc1ccc(C(=O)NC(c2cccs2)C(C)C)cc1 +COc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)c2cccnc12 +Cc1cn2nc(NCC3COc4ccccc4O3)sc2n1 +O=C(CC1(O)C(=O)Nc2ccc(Cl)cc21)c1ccccc1F +Cc1nccn1-c1ncccc1NC(=O)CCc1ccccc1Cl +Cc1cn(CC(=O)NCCOC(N)=O)c2ccccc12 +CCOC(CC)C(=O)Nc1cccc(Oc2cnccn2)c1 +OCCSc1nnc(NCc2ccccn2)s1 +Cc1nc(C)c(CNCC2(c3ccccc3)CCC2)s1 +Cc1ccc(NC(=O)CN(C)C(=O)c2cnc3ccc(C)cn23)nc1 +Cn1nc2n(c1=O)CCN(C(=O)Cc1ccccc1O)C2 +COc1ccccc1NCC(=O)N1CCCC1Cc1ccccc1 +CCc1nc(CCNC(=O)NC(C)Cc2c(C)noc2C)cs1 +COc1cc(C(=O)N2CCn3c(C)ccc3C2C)cc(OC)c1OC +Cc1nc(-c2cnccn2)nc(OCC(=O)c2ccc(F)cc2)c1C +Cc1cccc(NC(=O)N2CCN(c3cccc(O)c3)CC2)c1 +COc1cccc(-c2[nH]ncc2C(=O)NCC2CCCCC2)c1 +COc1cccc(C(=O)Nc2cccc(N)c2)c1O +Cc1cc(C(=O)Nc2ccc(Sc3ncccn3)cc2C)n(C)n1 +CN(C1CCCC1)S(=O)(=O)c1ccc2c(c1)CCN2 +CC(=O)Nc1ccc(C(=O)C(C)Sc2nnc(C3CC3)o2)cc1 +COC(=O)C1=C(C)NC(=O)CC1c1coc2ccccc2c1=O +N#Cc1ccccc1NC(=O)Cn1ccc(=O)c2cccc(F)c21 +CCN(CC(=O)NC)C(=O)c1ccc(-n2nc(C)c(Cl)c2C)cc1 +O=C(CN1C(=O)CNc2cc(F)ccc21)N1CCOCC1 +Cc1nnc(NCc2ccc(-n3cccn3)nc2)c(C#N)c1C +CC(NS(=O)(=O)c1cccs1)C(=O)N1CCCCC1 +Cc1nc(N2CCCC2C(=O)N2CCOCC2)sc1C +COCC(C)(O)CNC(=O)c1ccc2c(c1)OCO2 +COc1c(F)cc(-c2cn(CCc3cccs3)nn2)cc1F +Cc1ccc(C)c(OCC(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +Cn1c(=O)n(-c2ccccc2)c(=O)c2sc3c(c21)COC(C)(C)C3 +Nc1nc(-c2ccncc2)ccc1C(=O)N1CCCCC1 +COc1ccc(NC(=O)c2ccc(NC(=O)c3cccnc3)cc2)cc1 +Cc1ccc(OS(C)(=O)=O)c(-c2nc3ccccc3o2)c1 +O=C(NCc1ccncc1)Nc1cccc(C(F)(F)F)c1 +COc1cc(N)cnc1Oc1ccc(NC(C)=O)cc1 +OCc1cc(-c2ccc3c(c2)OCCCO3)nc2ccccc12 +COC(=O)C1CCN(S(=O)(=O)C2=Cc3ccccc3CC2)CC1 +CCCC1CN(C(=O)Nc2cc(NC(C)=O)ccc2C)CCO1 +COc1ccc(CC(=O)Nc2cc(C)nn2-c2ccc(C)cc2)cc1 +CCOC(=O)CSc1nnc(-c2ccco2)o1 +CC(OC(=O)c1csc(-c2cnn(C)c2)n1)c1ccccn1 +Cc1oc2ncn(C)c(=O)c2c1C(=O)N1CCc2ccccc2C1 +CC(C)C(=O)NCC1CCCN(C(=O)c2cc3ccccc3n2C)C1 +CC(C)S(=O)(=O)c1ccc(CCCCCO)cc1 +Cc1nc(C(c2cccc(F)c2)N(C)C)n(CCO)n1 +CC(C)CNC(=O)Cc1n[nH]c2cc(Cl)ccc12 +COCC(C)NC(=O)c1cnc2c(ccn2C2CCCCC2)c1 +N#CC1(NC(=O)CN2CCOC(c3nccs3)C2)CCCC1 +COc1c(O)ccc2c1C(c1ccccc1)NCC2 +Cc1ccc(NC(=O)c2ccc(OC(F)F)cc2)cc1N +Cc1cccc(C)c1NC(=O)CSc1nnc(-c2cccnc2)o1 +COCc1cccc(C(=O)N2CCOC(C)(C)C2)c1 +CC(C)(C)C(=O)N1CCC(C(=O)c2ccc3c(c2)NC(=O)CO3)CC1 +CCCc1cc(=O)oc2cc(OCC(=O)Nc3cc(C)on3)ccc12 +CC1(C)C(NC(=O)CSc2nncs2)C2CCOC21 +CCCC(C)NC(=O)c1c(OC)cccc1OC +CCOc1ccc(S(=O)(=O)N(CC)CC(F)(F)F)cc1 +CCS(=O)(=O)N(CCO)c1c(C)cc(C)cc1C +COc1cc(CCC(=O)N2CCNC(=O)CC2)cc(OC)c1 +O=C(Nc1ccc2c(c1)COC2)c1ccc2c(c1)OCO2 +CCCCn1c(SC2CC(C)OC2=O)n[nH]c1=O +CC(=O)N(C)CC(=O)N1CCCN(C(=O)c2cccc(C)c2)CC1 +COCCOC(=O)C1(c2cccc(Br)c2)CC1 +CCOC(=O)c1ccc(NC(=O)c2cccc(OC)c2)cc1 +CCCCCCN1CC2=C(Nc3ccccc3NC2=O)C1=O +CN(C(=O)Cc1cn2ccsc2n1)c1ccc(F)cc1 +CCCCNS(=O)(=O)c1sccc1Br +COc1cc(COC2CCCN(C(C)=O)C2)cc(OC)c1 +O=C(NCc1ccc(F)cc1)Nc1cccc(F)c1F +Cc1cc(C)c(CNC(=O)c2ccccn2)c(C)c1 +CC(C)C(=O)Nc1nnc(CCOc2ccccc2)s1 +COc1ccc2c(c1)N(CC1(CO)COC1)CCO2 +CC(NC(=O)c1ccc2c(c1)OCO2)c1ccc2c(c1)CCC(=O)N2 +COCn1nc(CO)cc1-c1cc(C)c(OC)cc1C +CCCCCNC(=O)C1CCN(S(=O)(=O)c2cnn(C)c2)CC1 +COc1cc2ccccc2cc1C(=O)NCc1ccc(NC(N)=O)cc1 +O=C(CCc1nc(-c2ccc(Cl)cc2)no1)N1CCOCC1 +COc1ccccc1C(=O)NCC(=O)Nc1ccc(F)cc1F +COc1ccc(-c2nc(-c3cccnc3)no2)cc1OC +CC(NS(=O)(=O)c1cccs1)c1ccccn1 +O=C(CCc1ccccc1)NCCCC(=O)N1Cc2ccccc2C1 +N#CCCSc1nccn1-c1ccccc1Br +Nc1cc(=O)n(C2OC(CO)C(O)C2O)c(=O)[nH]1 +CCC(=O)c1ccc2c(c1)N(CC(=O)NCC(C)C)C(=O)C(C)O2 +CC(C)c1noc(-c2ccc(NC(=O)NC(CCO)C3CC3)cc2)n1 +Cc1ccsc1CNc1ccc(NS(C)(=O)=O)cc1 +CN(C)C(=O)CC(c1ccc(O)cc1)c1cccc(O)c1 +CN(CCNC(=O)C1CC(=O)N(CC2CC2)C1)c1ccccc1 +Cc1nc2ccccc2nc1COC(=O)c1nccnc1N +COCC(=O)N1CCCC(c2cc(CCC(=O)N(C)C)nc(C)n2)C1 +Fc1ccc(N2CCN(Cc3nnnn3C3CCCC3)CC2)cc1 +Cc1nc(CNC(=O)C2CSc3ccccc32)c(C)s1 +CC(=O)c1ccc(S(=O)(=O)N=c2cccc(C)[nH]2)cc1 +COC(=O)c1coc(C2CCN(C(=O)OC(C)(C)C)CC2)n1 +Cc1cccc(S(=O)(=O)CCC(=O)NC2CC2)c1 +Cc1cc(NC(=O)C2CCCO2)n(-c2ccccc2F)n1 +CCc1nn(C)c(CC)c1CNc1cnn(CC(F)(F)F)c1 +CC(C)(C)c1cc(NC(=O)Cc2ccc[nH]2)n(-c2ncccn2)n1 +Cc1ccc(NC(=O)NCCS(N)(=O)=O)cc1 +Cc1cc(NCC(O)COCC(C)C)ccc1F +CCOC(=O)NCCC(=O)NC(C)(C)c1ccccc1 +CC(=Cc1ccco1)C1CC(=O)Nc2c1cnn2-c1ccccc1 +CCOc1ccc(N2CC(NC(=O)Nc3ccccn3)CC2=O)cc1 +Cc1ccc(-n2nc3c(c2-n2cccc2)CN(C(=O)C2CC2)C3)c(C)c1 +Cc1cnn(C)c1C(=O)Nc1nnc(-c2ccc3c(c2)OCCO3)o1 +FC(F)(F)c1ccc(NCC(C2CCOC2)N2CCOCC2)nc1 +CCn1c(=O)c(=O)n(CC(=O)NCCOC)c2ccccc21 +CC(CN1CCCC1=O)NS(=O)(=O)c1cnn(-c2ccccc2)c1 +CSc1cccc(NC(=O)CN2CCn3c(nn(C)c3=O)C2)c1 +CCOC(=O)N1CCN(C(=O)Nc2ccc(OC)nc2)CC1 +COCCNc1nc2cc3c(cc2s1)CCCN3C +Cc1ccccc1-c1nnn(CC(=O)N2CCc3ccccc32)n1 +Cc1cccnc1NC(=O)NCCNC(=O)CC1CCCCC1 +COCCCOc1ccccc1NC(=O)c1ccoc1 +CC1CCCN(C(=O)c2nnc3ccc(N4CCOCC4)cc3n2)C1 +COCCN1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +OCc1ccc(-c2cccc(C(F)(F)F)n2)cc1 +Cc1cccc(NC(=O)Cn2[nH]c(=O)c3ccccc3c2=O)c1 +O=C(NCc1ccccc1)NCc1ccc(OC2CCCC2)nc1 +CN(C(=O)NCC1COCCO1)C(c1ccccc1)c1ccccn1 +N#Cc1ccccc1CN1c2cccc3cccc(c23)S1(=O)=O +Cc1ccccc1C(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +Cc1sc(=O)n(CC(=O)NC2CCCC(C(F)(F)F)C2)c1C +CC(Nc1ncccc1C#N)c1cc(F)ccc1N1CCC(O)CC1 +Cc1cc(CNC(=O)CCCNC(=O)C(C)(C)C)ccc1F +Cc1ccncc1NC(=O)c1cccc(OCC(F)F)n1 +Cc1noc(C)c1S(=O)(=O)NC1(C(N)=O)CCCCC1 +COc1ccc2c(c1)CCCC2CC(=O)NCCCc1cn[nH]c1C +Cc1c(Cl)cccc1NC(=O)c1ccc(C(C)C)nc1N +CC(=O)NCCNC(=O)NC(C)COc1ccc(F)cc1 +O=S(=O)(NCc1cn2cc(Cl)ccc2n1)c1ccc(F)cc1 +CN(C(=O)CCCc1nc2ccccc2s1)c1ccc(F)c(F)c1 +COC(=O)C1CCC(NC(=O)c2scnc2C2CC2)CC1 +COc1ccc(OCCCc2nc3cccnc3o2)cc1 +CC(C)Oc1ccc(C(=O)N2CCN(c3cnccn3)CC2)cn1 +COC(=O)N(C)c1ccc(NC(=O)C2CCC2)cc1 +CCNC(=O)c1nn(-c2ccccc2C)nc1CO +COc1ccccc1OC1CN(c2noc(-c3ccccc3)n2)C1 +COc1cc(C)c(-c2cc(C)nc(N)n2)cc1OC +CN(C)C(=O)C1CC2CN(CCc3ccccc3)CC1O2 +Oc1ccc(CNc2cc(F)cc(F)c2)c(F)c1 +O=C(C1CCCC1)N1CCC2(CCCN(Cc3cccnc3)C2=O)C1 +O=C1CN(C(=O)NCCC(=O)NC2CCCC2)CCN1 +CCC(CC)C(=O)Nc1ccc(NC(=O)c2ccco2)cc1 +COCCCNC(C#N)c1cccc(Cl)c1Cl +CC(C)(C)C(C#N)NC(=O)CNC(=O)c1cc(-c2ccccc2)on1 +COC(=O)c1cc(C)sc1NC(=O)NC(C)c1cccnc1 +C#CCN1CCN(C(C(=O)NC2CC2)c2ccc(F)cc2)CC1 +COc1ccc(OCc2nnc3sc(-c4ccco4)nn23)cc1 +CCCCOc1ccccc1CNc1nncs1 +CC=Cc1ccc(OC(=O)C(C)NC(=O)c2ccoc2)c(OC)c1 +Cc1nc(-c2ncccn2)sc1C(=O)NC(C)(C)C +COCC(=O)Nc1ccccc1C(=O)NC(C)c1ccccc1 +O=C(c1cccs1)N1CCOC2CC(COc3ccccn3)CC21 +O=C(NCCc1ccccc1)c1ccccc1S(=O)O +Cc1cccc(NC(=O)C2CC(=O)N(c3cccc(C(C)C)c3)C2)n1 +COCCC1CCN(C(=O)CN(C)C(=O)c2ccncc2)CC1 +COc1ccc(Cl)c(NC(=O)NC(C(N)=O)C(C)(C)C)c1 +Cc1nnc(C(=O)Nc2cccc(F)c2)n1C1CC1 +CCc1nnsc1C(=O)NCc1ccc(OC)c(O)c1 +CCOc1ccnc(N2CCCN(c3nc(C(C)C)no3)CC2)n1 +C=CCCC(=O)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +Cc1noc(C)c1C(=O)NCCS(=O)(=O)c1ccccc1 +CCOc1ccc(Cl)c2c1CCNC2C(C)NC +CCCc1nnc(N2CCC3(CCCN(C)C3=O)C2)o1 +CCCn1cc(NC(=O)C(C)OCC(C)C)ccc1=O +Cc1nnc(NC(=O)c2cc(C(C)C)nc(N(C)C)n2)s1 +CC1CC(C)CN(C(=O)CCNC(=O)c2ccsc2)C1 +COc1ccc(-c2csc(-c3c(C)noc3N)n2)cc1 +O=C(Nc1cnc2ccccc2c1)c1csc2c1CCCO2 +CCS(=O)(=O)c1cc(F)ccc1NC(=O)NCC(F)F +COc1ccc(C(=O)Nc2cc(-c3ccco3)no2)c(C)c1 +Cc1cc(C(=O)NCC(=O)N(C)CC(N)=O)c(C)o1 +C=C(CO)C(O)(Cn1cncn1)c1ccc(F)cc1 +O=C(C1CCCC1)N1CCc2ccc(NS(=O)(=O)C3CC3)cc21 +Cc1ccccc1CN(C)C(=O)CSc1nc(N)nc(N)n1 +CC(C)c1cc(C(=O)NCCNc2cnccn2)nn1C(C)(C)C +N#Cc1ccc(NC(=O)c2c[nH]c3ccc(F)cc3c2=O)cc1 +Cc1noc(C2(NC(=O)Cc3ccsc3)CCCCC2)n1 +COC(=O)C1=C(C)C(C(=O)Nc2ccc(F)cc2F)=NC1C +COC(=O)C(NC(=O)Nc1ccc2nccnc2c1)C(C)C +CC(c1cccnc1)N(C(=O)COCC1CCCO1)C1CC1 +Cc1csc(Sc2ccc3c(c2)NC(=O)C3N)n1 +FC(F)(F)CCN(Cc1cnc2cnccn12)C1CCC1 +CC(C)C(=O)N1CCCC(c2ncncc2S(C)(=O)=O)C1 +CN(C)c1nc2ncnc(SCC(=O)Nc3ccccc3)c2s1 +COC(=O)CCC(=O)Nc1ccc(NC(=O)C(C)C)cc1 +Cc1cnc(CCNCc2ccc(S(C)=O)cc2)s1 +Cc1cc(N2CCC(O)C2)ncc1Br +CC(Nc1ccccc1C#N)c1ccc2c(c1)OCCO2 +O=C(CC(F)(F)F)N1CCN(C(=O)Nc2cccnc2)CC1 +CCC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)c1ccccc1 +Cc1csc(-c2cnncc2Br)c1 +COC(=O)C1=C(C)NC(=O)CC1c1cccc(OC)c1OC +CC(C)CCC(C)(O)CNC(=O)NCC1CN2CCCCC2CO1 +COc1cccc(CNC(=O)c2ccc3c(c2)NC(=O)C(C)S3)c1 +COC(=O)CC(C)C(=O)N1CCCC1C(=O)N1CCN(C)CC1 +Cc1ccc(CN2CC(C(=O)OCc3ccccn3)CC2=O)cc1 +CSc1ccc(NC(=O)NCCc2cscn2)cc1F +Cn1ccc(C(=O)NC2CCN(C(=O)c3ccco3)CC2)cc1=O +CCN(Cc1ccccc1C)C(=O)c1cnc(C)cn1 +Cc1cccc(C)c1OCC(C)NC(=O)C1CCOC1 +Cc1cccc(NC(=O)CNC(=O)CC2C=CCC2)c1C +CCn1cc(CCC(=O)NCc2ccc(OC)cc2)c(C)n1 +CC(=O)c1cccnc1-c1nc2ccccc2s1 +CCS(=O)(=O)NCCN1CCCc2cc(F)cc(F)c21 +Cc1ccc(CN(C)C(=O)Cn2c(=O)oc3cc(Cl)ccc32)o1 +CC(Sc1nccn1C1CC1)C(=O)NCc1ccc(Cl)cc1 +Cn1nnnc1SCC(=O)Nc1nnc(-c2ccsc2)o1 +CCc1ccc(NC(=O)Cn2nnc(-c3ccccc3F)n2)cc1 +CN(C(=O)CCc1nc(-c2ccccn2)no1)C1CC1 +COC(=O)c1cc(-c2ccc(SC(C)C)cc2)n[nH]1 +Cc1ccccc1C1(O)CCN(C(=O)Cn2cnnn2)C1 +CC(=O)N1CCN(C(=O)NCc2cccnc2OC(C)C)CC1 +CC(=O)N1CCCC(C(=O)N=c2[nH]c3cc(Cl)ccc3n2C)C1 +Cc1noc(C)c1Cc1nn2c(Cc3ccccc3)nnc2s1 +COCc1ncc(C(=O)NCCCN2CCOCC2)c(N)n1 +Cc1noc(C)c1C(C)NC(=O)NCC(=O)NC(C)(C)C +c1cncc(OC2CCC3C2OCCN3Cc2ccoc2)c1 +CC(C(=O)N(C)CCC#N)N1CCOC(c2ccccc2)C1 +CC(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1C +O=C(Cc1ccc[nH]1)Nc1ccc(-n2cnc3ccccc32)nc1 +CCN(CCC#N)C(=O)c1cc2c(s1)CCCC2 +O=C(Nc1ccc(SC(F)F)cc1)c1cccnc1 +COc1ccc(SC(C)C(=O)NCC(=O)NC2CC2)cc1 +CC(=O)c1ccc2c(c1)N(CC(=O)N1CCCCCC1)CCO2 +CC(C)Cn1nccc1NC(=O)Cc1ccccc1F +COc1ccc(NC(=O)N2CCOCC2)cc1F +O=C(NCC1Cc2ccccc21)c1scnc1C1CC1 +CCCCN(CCOC)C(=O)Nc1ccc(F)c(F)c1 +COc1ncccc1NC(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +O=C(NCCOc1cccnc1)c1ccccc1Br +CCOCc1cccc(NC(C)C(=O)Nc2c(C)nn(C)c2C)c1 +Cc1nc2ccc(C(=O)OCc3ccc(C(N)=O)cc3)cc2nc1C +O=C(NCCCSc1ccc(F)cc1)c1ccc2c(c1)OCCO2 +Cn1ccc(C(=O)NC(c2ccccc2)c2cccs2)cc1=O +COCCNc1nc(Cc2ccc(Cl)c(Cl)c2)no1 +Cc1ccc(F)c(NC(=O)N(C)Cc2nccn2C(F)F)c1 +CN(CC(O)C1CC1)C(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +O=C(NCCc1c[nH]c2ccc(F)cc12)c1ccncc1 +O=C(CN1CCCCCC1=O)NCc1ccc(OC(F)F)cc1 +CC1CCc2c(C(=O)NC(C)CN3CCOCC3)csc2C1 +COc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cn1 +CCNC(=O)CN(C)S(=O)(=O)c1ccc(Cl)c(C#N)c1 +CCC1CN(CC(=O)N2CCC(C(N)=O)CC2)c2ccccc2S1 +O=C(NC1CCN(C(=O)C2CCC2)CC1)c1ccccc1 +O=C(C1CC1)N1CCC(c2nnc(-c3ccc(F)cc3)o2)CC1 +CC(C)(O)C(C)(C)NC(=O)Nc1ccc(C(N)=O)c(Cl)c1 +CNS(=O)(=O)Cc1ccc(CNC(=O)c2ccc(C)[nH]c2=O)cc1 +Cc1cnc(C)c(-c2cccc(-c3ccn(Cc4nnc(C)o4)n3)c2)n1 +O=C(c1cn(-c2ccc(F)cc2)nn1)N1CCCCC1 +CCCCN(Cc1ccccc1F)C(=O)c1ccc(C)[nH]c1=O +CC(Cn1cncn1)NS(=O)(=O)c1cccc(S(C)(=O)=O)c1 +CCN(Cc1ccco1)C(=O)NCCNC(=O)C(C)C +CCN1C(Cl)=Nc2c(C)cc(C)cc2S1(=O)=O +CCCc1nnc(N2CCC3(CCC(=O)N(CCO)C3)CC2)s1 +CC(C)(C)C(=O)Nc1nnc(Cc2ccccc2F)s1 +COc1ccc(Br)cc1-c1cc(N)nc(C)n1 +CCOc1cc(C)ccc1NC(=O)c1csc(C)n1 +CCc1nnc(SCC(=O)Nc2ccncc2)o1 +CC(CN(C)C(=O)c1cccc(-c2ncn[nH]2)c1)c1nccs1 +CN1C(=O)Cc2cc(NC(=O)C34CC5CC(CC(C5)C3)C4)ccc21 +Cc1noc2ncc(C(=O)NCCCCOc3ccc(F)cc3)cc12 +CCCCN1CC(C(=O)Nc2ccc(OC)cc2)CC1=O +CCN(Cc1ccc(C(=O)NC)cc1)c1cccc(F)c1 +Cc1nccn1-c1ccc(C(=O)NCC(F)(F)F)nn1 +CC(C)(C)C(=O)NCC(=O)NC1CCN(C(=O)c2ccoc2)CC1 +CN(C(=O)c1ccc(-c2ccccn2)[nH]c1=O)C(C1CC1)C1CC1 +CCOC(=O)C(NC)c1ccc(NC(C)=O)c(F)c1 +COc1ccc(C(=O)NCC(c2ccccc2)N2CCOCC2)nn1 +COc1ccc(C(O)C(=O)Nc2ccc(NC(C)=O)cc2)cc1 +CN(Cc1ccc(O)cc1)C(=O)COc1ccccc1 +Cc1ccccc1-c1noc(CN2CCOC(c3nccs3)C2)n1 +CCn1c(SCC(=O)NCC(C)C)nnc1C1CC1 +NC(=O)NCCNc1cc(C(F)(F)F)nc(-c2ccccn2)n1 +COC(=O)c1ccccc1NC(=O)N(C)Cc1ccc(C#N)cc1 +O=C(c1cnccn1)N1CCOCC2(CCN(c3ncccn3)C2)C1 +CCNC(=O)CN1CCC2(CCC1=O)CNC(=O)c1ccccc1O2 +O=C(NC1CCCCC1)C1CSc2nccc(=O)n2C1 +CNC(=O)COc1cccc(-c2nc(C(C)C)no2)c1 +Cc1ccc(Cl)cc1NC(=O)c1cnc2ccccn2c1=O +Cc1cc(NC(=O)NCCSc2nccn2C)n(C(C)C2CC2)n1 +COc1cccc(C(CNC(N)=O)c2c[nH]c3ccccc23)c1OC +O=C(C1CC1c1ccco1)N1CCC(Nc2cccnn2)CC1 +O=C(COc1ccc(C(=O)c2ccccc2)cc1)Nc1nccs1 +Cc1ncc(CNC(=O)NCC(=O)Nc2ccc(Cl)cc2)s1 +CC(C)N(c1cnn(C)c1)S(=O)(=O)c1cn(C(C)C)cn1 +CC(=O)Nc1ccc(C(=O)NCc2cnn(Cc3ccccc3)c2)cc1 +CCOC(=O)C(C)CNC(=O)Nc1ccc(C(F)(F)F)cc1 +CCn1cnnc1CNC(=O)C1CC(=O)N(C2CC2)C1 +Cn1cnnc1C1CCCN1C(=O)c1ccc2[nH]cnc2c1 +COc1cc2c(cc1CNCCc1nnc3n1CCC3)OC(C)C2 +Cc1noc(C)c1CCCNS(=O)(=O)c1ccc(F)c(C#N)c1 +COCCCNC(=O)NC(C)c1ccc(C(C)C)cc1 +CC1(C)Nc2ccccc2N(CC(O)CO)C1=O +CC(=O)c1ccc(OC(=O)C2CCCN2S(C)(=O)=O)cc1 +Cc1noc(C)c1C(C)NS(=O)(=O)c1cccc(C(F)(F)F)c1 +Cc1nnc(NCC(O)c2ccc(F)c(F)c2)c(C#N)c1C +O=C(NCc1ccc(COCC(F)(F)F)cc1)Nc1cccnc1 +COc1ccc2c(c1O)CCNC2c1ccc(F)cc1F +NC(=O)C1CCN(C(=O)C2(c3ccccc3F)CC2)c2ccccc21 +COc1ccc(NC(=O)c2oc3ccc(F)cc3c2C)cc1OC +COc1cc(CC(=O)NCC(O)c2ccco2)ccc1C +CCn1cc(C2C(C(N)=O)=C(C)Nc3ncnn32)cn1 +CC(O)CN1CCN(C(=O)c2cccn2-c2ncccc2Cl)CC1 +O=C(NCc1ccon1)NC1(Cc2ccccc2)CCCC1 +COc1ccc(C)cc1NC(=O)c1cccc(OCC(F)F)n1 +CCS(=O)(=O)N1CCCC1C(=O)c1ccc(C)c(C)c1 +O=C1CC(Nc2ccccc2)CN1c1ccccc1 +CN(C1CCCCC1)S(=O)(=O)c1ccc(F)cc1 +O=C(c1cnc(C2CC2)s1)N1CCC(Nc2cccnn2)CC1 +CC(CC#N)N(C)C(=O)Nc1ccccc1OCCc1ccccc1 +CC(C(=O)NCCCN1CCOCC1)n1cccn1 +CCc1nc(CCNC(=O)c2cccc3[nH]ncc23)sc1C +Cc1ccc(S(=O)(=O)N(CCO)C(C)C)cc1N +Nc1ccc(S(=O)(=O)c2ccc(N)cc2O)cc1 +Cc1cc(C)nc(SCC(=O)NC2(c3noc(C)n3)CCCC2)n1 +Cc1cccc(CS(=O)(=O)N2CCC(Oc3cccnc3)CC2)c1 +Cc1cccc2nc(CSc3nccc(=O)[nH]3)cn12 +Cc1noc(C)c1CC(=O)N1CC=C(c2ccccc2Cl)CC1 +COc1ccc2c(=O)c(-c3ccc(N)cc3)c(C)oc2c1 +COC(=O)CCc1cc(Br)c(OC)c(OC)c1OC +CCc1nnc(CNC(=O)C2CC(=O)Nc3ccc(OC)cc32)s1 +Cc1cc(C(=O)NCC(=O)N2CCc3ccccc3C2)nn1C +Cc1nc(C)c(CC(=O)Nc2ccc(N(C)C)nc2)c(=O)[nH]1 +CCCCN(CCOC)C(=O)Nc1ccccc1F +O=C(NCCOCCO)Nc1cc(F)c(C(F)(F)F)c(F)c1 +COCC(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1 +CS(=O)(=O)NCCc1ccc(OCc2ccccc2)cc1 +CC1(O)CCCN(C(=O)CCc2cc(F)ccc2Br)C1 +O=C(C1CCCCC1CO)N1CCc2ccccc2C1 +Cn1c(=O)oc2cc(Nc3nccnc3C#N)ccc21 +CC(C)Cc1nnc(C(C)Sc2nc3ccccc3c(=O)n2C)o1 +O=C(CNC(=O)c1ccco1)Nc1cccc(C(=O)c2ccccc2)c1 +CCn1ncc(Cl)c1C(=O)N1CCc2ccccc21 +CC(OCC1CCCCO1)C(=O)N(C)Cc1ccc2c(c1)OCCO2 +CCCNC(=O)c1cccc(C(=O)Nc2ccc3c(c2)OCO3)c1 +Cc1cc(=O)c(O)c(CN(C)CCO)n1CC(C)C +CCOC(=O)N1CCN(CC(=O)NC2CCCC(C)C2C)CC1 +CC(=O)c1cnn(Cc2cccc(C(F)(F)F)c2)c1 +CC(C)CCNC(=O)c1[nH]cnc1C(=O)NCc1ccccc1F +CCN1CC(C(=O)Nc2ccc(C#N)c(Cl)c2)CC1=O +Cc1nc(-c2cc(-c3ccc(C(F)(F)F)cc3)nc(N)c2C#N)c[nH]1 +CCNC(=O)c1cccc(NC(=O)N(C)Cc2ccc(F)cc2)c1 +Cn1cccc1C(O)CNC(=O)CCc1ccccc1 +Cc1nc(N2CCOCC2C(N)=O)c2c(CC(C)C)csc2n1 +CCC(C(=O)OCC(=O)N1C(C)CCCC1C)c1ccccc1 +CC(C)CN1CCN2C(=O)C(CO)NC(=O)C2C1 +CCC(CO)NC(=O)Nc1cccc(C(=O)NC(C)(C)C)c1 +CCCn1nnnc1CN1CCCC(c2nc3ccccc3o2)C1 +Cc1csc2nc(-c3ccc4c(c3)OCCO4)c(N)n12 +CCOc1ccc(CNC(=O)c2ccccc2NS(C)(=O)=O)cc1 +CCCOc1ccc(-c2nnc3ccccn23)cc1N +CCCCNC(=O)c1onc(-c2cccc(F)c2)c1N +COc1cccc(OCc2nc3ncccc3o2)c1 +Cc1ccc(C(=O)NC2CCN(c3cn[nH]c(=O)c3Cl)CC2)o1 +O=C(c1ccncc1F)N1CCC2(CCCCC2)C1 +Cc1ccc(C)c(OCC(=O)Nc2sccc2C(N)=O)c1 +Cc1ccc(C(C)C)c(OCC(=O)N2CCOCC2c2ncon2)c1 +CCn1nc(C(C)C)cc(-c2nnc(NC(C)C)s2)c1=O +CS(=O)(=O)c1cccc(C(=O)N2CCN(c3ncccn3)CC2)c1 +CCN(CC)C(=O)c1c(C)nc(N)nc1-c1ccc(Cl)cc1 +Cn1cc(C(=O)N2CCN(S(C)(=O)=O)CC2)c2ccccc21 +CCc1noc(C)c1C(=O)OC(C)c1nc(C(C)(C)C)no1 +CC(=O)c1ccccc1NC(=O)CCCOc1ccccc1 +COC(=O)CCNC(=O)Cn1ccc2ccccc2c1=O +CCN(Cc1ccccc1)C(=O)CSc1nncc2ccccc12 +Cc1ccc(NC(=O)c2scnc2C)c(F)c1 +Cc1ccc(NC(=O)NC(C)c2cccc(N3CCCC3=O)c2)cc1 +c1coc(-c2nnc(SCc3c[nH]c4ccccc34)o2)c1 +CN1CCN(C(=O)COc2ccccc2Cl)C(c2ccccc2)C1 +Cc1cc(C(=O)N2CCC(c3ccc4c(c3)OCO4)C(O)C2)no1 +COC(C)C(=O)N1CCN(c2cc(N)nc(N)n2)CC1 +CCCN(C(=O)Cn1nc(C)ccc1=O)C1CCc2ccccc2C1 +O=C(Cc1ccc(F)cc1)NCC(=O)c1ccccc1 +O=C(Nc1ccccc1)C1CCN(C2=NC=NC3=NC=NC32)CC1 +CC(C)C(=O)N1CCC(C(=O)OC(C)c2ccccn2)CC1 +Cc1noc(C)c1CC(=O)OCc1nc2ccccc2[nH]1 +O=S(=O)(Cc1ccccc1Cl)Nn1cnnc1 +Cc1oc(C)c(C(=O)NCCS(N)(=O)=O)c1C +CC(=O)c1sc2ncn(Cc3ccc(F)cc3)c(=O)c2c1C +CCOC(=O)c1snc(-c2ccc(F)cc2)c1N +Cc1nc(SCC(=O)N(CC(C)C)C2CC2)oc1C +CCOc1cccc(C(=O)Nc2ccn(CC)n2)c1 +O=C(Nc1ccccn1)C1(c2ccc(F)cc2)CCC1 +CCOC(=O)c1sc(NC(=O)c2cc3cc(F)ccc3[nH]2)nc1C +CNc1cc(-c2ccc(O)c(C(C)=O)c2)c2cc[nH]c2n1 +CCNC(=O)NC1(C(=O)NCCc2cccc(OC)c2)CCCC1 +Cc1ccn2cc(-c3ccc(NC(=O)C4CC4)cc3)nc2c1 +COC(=O)N(C)CC(=O)NC(C)Cc1ccccc1Cl +COc1cc(OC)cc(C(=O)NCC(=O)NC(C)(C)C)c1 +CCCC(NC(=O)Cc1ccc[nH]1)c1cccc(C(F)(F)F)c1 +CCOC(=O)C1=C(CNc2ccc(F)cc2C)NC(=O)NC1 +CS(=O)(=O)N1CCc2cc(C(=O)OCC3CC=CCC3)ccc21 +O=C(Nc1nnc2n1CCS2)C1CC(=O)N(c2ccc(F)cc2)C1 +Cc1cccc(Cn2nccc2NC(=O)Cc2c(C)nn(C)c2C)c1 +COc1cc(Cl)c(C(=O)NCCCO)cc1Cl +Cc1nc(-c2ccccc2)sc1C(C)N(C)Cc1cnnn1C +NC(=O)c1cccc2c1CCCN2C(=O)CCc1cc(F)ccc1F +C=CCNC(=O)NCc1cc(OC)c(O)c(OC)c1 +Cc1ccc(NC(=O)C2CCCO2)c2cccnc12 +Cc1cc(C)n(CC(C)CNC(=O)c2ccc(C#N)cc2)n1 +CCC1CN(c2nn3cc(C)nc3s2)CCN1CCOC +CCc1cc2c(N3CCN(C(C)=O)CC3)ncnc2s1 +O=C(CC1CCN(c2ncnc3ccccc23)CC1)N1CCCC1 +Cc1csc2nc(CSc3nnnn3C)cn12 +O=C(Nc1ccc2ncccc2c1)c1nnn(-c2ccc(F)cc2)n1 +CC(C)N1CC2(CCC1=O)CCN(C(=O)CCc1cnn(C)c1)CC2 +CC(C)(C)CC(=O)N1CCN(c2ccc(S(N)(=O)=O)cc2)CC1 +CCC1C(=O)NCCN1Cc1cccn1Cc1cccs1 +Cc1ccc(N2CC(NC(=O)Nc3nccs3)CC2=O)cc1 +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1ccc2[nH]ccc2c1 +O=C(c1cnco1)N1CCC(c2cc(CCO)[nH]n2)C1 +CC(C)CCc1cc(=O)[nH]c(N2CCOCC2)n1 +CCN(CCC#N)C(=O)c1ccc(C(C)(C)C)cc1 +Cc1ccc2nc(C)c(C(=O)N3CCN(c4cccnc4)CC3)cc2c1 +Cn1nccc1CNC(=O)Nc1ccccc1N1CCCC1=O +O=C(N1CCCC1)N1CCN(c2ccccc2F)CC1 +O=C(Nc1ccnn1Cc1ccc(Cl)cc1Cl)c1ccoc1 +CC(C)OC(=O)Cn1cc(C#N)c(=O)c2cc(Br)ccc21 +COc1ccc(OC)c(CN(C)C(=O)CCc2cccnc2)c1 +CCOC(=O)c1sc2ncn(CC(=O)C(C)CC)c(=O)c2c1C +CCn1nc(C)c(CNC(=O)NCc2ccc(C#N)cc2F)c1C +CCCCn1cc(-c2cc(C(=O)N(C)C)c3cc(C)ccc3n2)cn1 +CCC1Oc2cc(O)ccc2N(Cc2ccccc2F)C1=O +CCS(=O)(=O)NCCSc1nnc(-c2ccccc2F)n1N +Nc1ccc2c(O)cc(=O)n(Cc3ccccc3F)c2c1 +COc1ccc(N(C)C(=O)c2ccoc2C)cc1OC +O=C(CNC(=O)C1CCCO1)Nc1cc(Cl)ccc1Cl +COc1ccc(C)cc1CCN1C(=O)c2ccccc2S1(=O)=O +CCOC(=O)C(C)NC(=O)N1CCN(C)c2ccccc21 +CCC(=O)c1ccc2c(c1)N(S(C)(=O)=O)CC(C)O2 +CCOc1ncccc1NC(=O)NCC(O)c1ccccc1OC +COCc1cc(C(=O)N(C)CCOc2cccc(C)c2)ccc1F +NC(=O)Nc1ccc(-c2csc(N3CCCCC3)n2)cc1 +CCC(=O)N1CCCC(C(=O)NCCc2ccc(F)cc2C)C1 +CCOc1ccc(C(C)NC(=O)CN(C)S(C)(=O)=O)cc1 +CCC(CC#N)NC(=O)c1cccc(Cl)c1Cl +CC1CN(C2CCN(C(=O)NC(C3CC3)C3CC3)CC2)CCO1 +CCOCCCNS(=O)(=O)c1ccc(C)c2c1CCCN2 +COCCc1nc(Cn2ccnc2)n(-c2ccc(OC)cc2)n1 +Cn1nc(C2CCC2)cc1NC(=O)Cc1cccc(F)c1 +Cc1cc(C(=O)Nc2ccc(C(=O)OC(C)C)cc2)no1 +COC(=O)C(CC(C)C)NC(=O)c1ccc2ccn(C)c2c1 +CC1OCCC1S(=O)(=O)N1CCC2(CCCC2)CC1 +CCCOc1ccc(-c2csc(N3CCCC3=O)n2)cc1 +Cc1[nH]ncc1C(=O)NC1CCN(c2ccc(C(F)(F)F)cc2)C1 +O=C(CCC=Cc1ccccc1)NCc1cn(-c2ccccc2)nn1 +COc1cccc(OCc2ccc(C(=O)NC(C)C)o2)c1 +Cc1cccc(C(=O)Nc2sc3c(c2C#N)CCC3)c1 +CCOc1ccc(CCC(=O)Nc2cc(C)on2)cc1N +CS(=O)(=O)NCC1CCN(C(=O)Oc2ccccc2)CC1 +Cc1cc2c(cc1F)CCNC2c1cnccc1Cl +COc1ccc(CCC(=O)N2CCCCCC2)cc1OC +CCCCNC(=O)COC(=O)c1cc(F)ccc1Cl +Cc1cccnc1CC(C)Nc1nccc(C(F)(F)F)n1 +CC(=O)C(C)Sc1ncc(-c2ccccc2)n1CC1CCCO1 +O=S(=O)(Nc1ccncc1)c1ccc(F)cc1 +O=C(Cc1noc2ccccc12)NCc1ccc(NC(=O)C2CC2)cc1 +Cc1ccc(NC(=O)c2ccc(=O)[nH]c2)c(Br)c1 +Cc1scc(C(=O)N2CCN(Cc3ccc(F)cc3)CC2)c1C +CSc1ccc(NCC(=O)NCC2CC2)cc1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)NCC(=O)NC1CC1 +Cc1ccccc1-c1nnc(CN2CCOCC2C2CC2)o1 +CCCCOc1cccc(CNC(=O)c2nccnc2N)c1 +COc1ccc(NC(=O)CC(C#N)c2ccccc2C)cc1 +CCn1c(SCc2ccccc2F)nc2c1c(=O)n(C)c(=O)n2C +COCC(C)NC(=O)Cn1ccc(=O)n(C)c1=O +COc1ccc(OCCN(C)S(C)(=O)=O)cc1 +O=S(=O)(Nc1ccc(-n2cccc2)cc1)c1ccc(F)cc1 +Cc1ccc(NC(=O)N2CCC(CN3CCOCC3)CC2)cc1C +Cc1cccc(C(C)C)c1NC(=O)C1CCCN(S(C)(=O)=O)C1 +COc1ccc(-c2nc(Cn3nc(-c4ccco4)oc3=O)co2)cc1 +CC(=O)Nc1cccc(C(=O)N2CCC(Cc3ccccc3)CC2)c1 +Cc1ccc(CC(=O)NC(C)c2ccc(C)s2)cn1 +CC(C)(C)OCCn1nc(C(F)(F)F)c2cnccc21 +CCC(NC(=O)NCC1CCC1)c1ccc(Cl)cc1 +COc1ccc(C(=O)N(C)Cc2ccc(C)s2)c(O)c1 +O=C(CCc1cccc(OC2CCCC2)c1)N1CCN(CCO)CC1 +Cc1cccc(CNC(=O)c2sccc2C#N)n1 +COC(=O)c1sc2cc(C)n(C3CC3)c(=O)c2c1N +CN(Cc1nc(-c2cccs2)no1)CC1COc2ccccc2O1 +CC(C)(C)C(=O)N1CCN(c2cc(-n3cccn3)ncn2)CC1 +Cc1cc(C)c(S(=O)(=O)Nc2ccccc2-n2ccnn2)c(C)c1 +Cc1nc2c(c(NC(=O)c3ccco3)nn2C)c(C)c1Cl +Cc1ccccc1S(=O)(=O)Nc1cc(N)ccc1F +CCCc1noc(C2CCN(C(=O)COCC)CC2)n1 +CC(C)OCC(=O)Nc1ccc(Oc2cccc3[nH]ccc23)nc1 +CN(C1(C#N)CCCC1)S(=O)(=O)c1cccc2ncccc12 +COc1ccc(CNC(=O)NCC#CCOc2cccnc2)cc1 +CCN1CCc2nc(NC(=O)c3ccc(C)cc3)sc2C1 +Cc1cc(C)n(-c2ccc(NC(=O)NCc3ccnn3C)cc2F)n1 +O=C(COCc1nnc(C(=O)Nc2ccccc2)s1)NC1CC1 +CCOCc1ccccc1CNC(=O)C1CCOCC1 +CN(CC(N)=O)C(=O)c1cn(-c2ccccc2)nn1 +CNS(=O)(=O)c1ccc(C(=O)NC(C)(C)c2cccc(F)c2)o1 +CC(c1ccccc1Cl)N(C)C(=O)CNC(=O)OC(C)(C)C +Cc1ccccc1C(=O)NCC(=O)NCCc1nc2ccccc2[nH]1 +O=C(NC1CCSc2ccccc21)c1ccc2ccccc2n1 +CC(C)C1COC(=O)N1Cc1cnn(-c2ccccc2F)c1 +Cc1cccc(C2CCCN(C(=O)CN3CCCCCC3=O)C2)c1 +CCOc1ccccc1C(=O)Nc1cc(-c2ccccn2)no1 +CCNC(=O)C(C)(C)CNC(=O)c1cnc2ccc(C)cn12 +COCC(C)NC(=O)c1cccc(OCc2csc(C)n2)c1 +O=C(Nc1ccc2c(c1)COC2)N1CCC(C(F)(F)F)CC1 +CC(=O)Nc1cccn(Cc2ccc(Cl)c(Cl)c2)c1=O +C#CCN(CC#CC)C(=O)Nc1cccnc1OC +CC(=O)NC(C)(C)c1noc(-c2sc3ccc(F)cc3c2C)n1 +Cc1nn(-c2ccc(F)cc2)c(C)c1CN1CCOC2(CCC2)C1 +Cc1[nH]ncc1CCCNC(=O)N(C)Cc1ccoc1C +O=C(Nc1cnn(-c2cccc(C(F)(F)F)c2)c1)N1CCOCC1 +CCN(CCO)C(=O)Nc1ccc(SC)cc1 +CCN1CC(C(=O)N2CCc3sccc3C2)CC1=O +O=C(c1cccs1)N1CC(OCc2ccc(F)cc2Cl)C1 +CCN(C)c1ccc(C(=O)N2CCOCC2C2CC2)cc1 +C#CCn1c(CCCNC(=O)c2ccccc2C)nc2ccccc21 +COCc1cccc(NC(=O)CC2(O)CCCCC2)c1 +CCCC(=O)Nc1ccc2c(c1)NC(=O)CS2 +CC(C)CC(CO)NC(=O)c1ccc(Cl)cc1 +Cc1cccc(C)c1NC(=O)Cn1nc(-c2ccccc2)ccc1=O +CN(C)c1ncc2c(n1)CCCC2NC(=O)CCc1ccncc1 +Cc1oc(-c2cccs2)nc1C(=O)NC(C)COCC(F)(F)F +CCNC(=O)CN1CCN(C(=O)C(C)CC2CCCC2)CC1 +CC(=O)Nc1cccc(C(C(F)(F)F)C(F)(F)F)c1 +CN(CCO)C(=O)CCOc1ccc2c(c1)CCC2 +Cc1ccc(CN2C(=O)CCC2C(=O)NCc2ncn(C)n2)cc1 +O=C(c1cc[nH]n1)N1CCOC2(CCCN(c3ncccn3)C2)C1 +CCn1ccnc1CN1CCCN(C(=O)c2cccc(C#N)c2)CC1 +Cc1nc(C)c(C(=O)N2CCC(c3cc4ncccc4cn3)CC2)o1 +CC(=O)NC(C)(C)c1noc(CCCc2nc(C(C)C)no2)n1 +Cc1cc(C)cc(C(=O)Nc2cnn(CC(=O)NC3CCCC3)c2)c1 +CCN1CC(C(=O)NCCc2nc(C)cc(C)n2)CC1=O +COCCN(C)C(=O)Nc1cccc(C(F)(F)F)c1 +CCC(C)C(NC(=O)c1ccccc1)C(=O)N1CCN(C)CC1 +CC(CO)CNC(=O)CCNC(=O)NC1CCCCC1 +COc1ccc(OC)c(CNC(=O)c2cc(-c3cccnc3)[nH]n2)c1 +N#Cc1cc2c(nc1SCc1nnc(C3CC3)o1)CCCC2 +Cc1cc(NC(=O)N2CCN(c3ncccc3Cl)CC2)n(C)n1 +CCC(=O)NCc1nnc(C(=O)Nc2cccc(Cl)c2)s1 +Cn1nnnc1SCc1nc2sc3c(c2c(=O)[nH]1)CCC3 +Cc1ccc2nc(NC(=O)CSc3nncs3)sc2c1 +Cc1cccc(NC(=O)C2CC(=O)N(CC(C)C)C2)n1 +OCCc1cc(CC2(NCc3cccc4c3OCO4)COC2)no1 +CNC(=O)CNS(=O)(=O)c1cccc(Cl)c1 +CC(=O)N(C)c1ccc(NC(=O)OCc2ccccc2)cc1 +COC(=O)CCNC(=O)C1CNCc2cccc(Cl)c21 +CCc1noc(CN(C)C(=O)NC2CCCC(CC)C2)n1 +O=c1ccnc(SCc2ccc(Cl)cc2)[nH]1 +CC(NC(=O)NC(C)c1ccc2c(c1)NC(=O)CO2)c1ccncc1 +CC(C)C(=O)Nc1cccc(CS(=O)(=O)NC(C)(C)C)c1 +CS(=O)(=O)NCCc1csc2nc(-c3ccccc3)nn12 +Cn1ncnc1NC(=O)NC1CCOC(C2CC2)C1 +CCOC(=O)C1CCN(c2cc(F)cc(F)c2)CC1 +CCC(CC)C(=O)NC1CCSc2ccc(F)cc21 +CCCCN(CCO)C(=O)Nc1ccccc1OC +CC(C)Sc1ccc(-c2cc(=O)[nH]c(=O)[nH]2)cc1 +Cc1ccc(S(=O)(=O)NC(C)c2c(C)noc2C)cc1F +CCS(=O)(=O)N(C)Cc1csc2ccccc12 +N#Cc1cccc(C(=O)N2CCC3C2CCC(=O)N3c2cccnc2)c1 +CCC(NC(=O)CCCOC)c1cccc(Cl)c1 +COc1ccc(NC(=O)N2CCCC2)cc1OCC(F)(F)F +COC(CNC(=O)c1cc2ccc(C)cc2nc1C)c1ccccc1 +O=S1(=O)CCCN1c1ccc(Br)cc1C(F)(F)F +N#Cc1ccc(CN2CCCN(C(=O)CCC3CCCC3)CC2)cc1 +O=C(Cc1csc(Nc2ccccn2)n1)NC1CC1 +COCCNC(=O)c1n[nH]c2cc(Cl)ccc12 +CCOCC1CCCN(C(=O)c2cccc(OCC(F)F)n2)C1 +COCC1CCCN(C(=O)Nc2ccc(C(F)(F)F)cc2)C1 +COc1ccc(-c2noc(C(C)O)n2)cc1OC +CCC(CC)NC(=O)C1CCN(C(=O)c2cccs2)CC1 +O=C(c1ccco1)N1CCN(c2cnnc(N3CCOCC3)c2)CC1 +O=C(c1ccncc1)N1CCC(CCOCc2ccc(F)cc2)CC1 +COC(=O)NCC(=O)Oc1ccc2oc3c(c2c1)CCCC3 +COC(=O)C1(NC(=O)c2csc(C)n2)CCCCC1 +COc1ccc(CNC(=O)CCCn2c(=O)oc3ccccc32)cc1 +CN(C(=O)c1ccncc1F)c1ccc(F)c(F)c1 +CCn1ccc(NS(=O)(=O)c2ccc(OC)c(OC)c2)n1 +O=C(Nn1cnc2ccccc21)c1ccc(-c2cnco2)cc1 +CCn1nc(C)c(CNCCc2ncc(C)s2)c1C +CC(=O)NC(CC(=O)Nc1cccn(C)c1=O)c1ccc(Cl)cc1 +Cc1nnc(C(C)Nc2ccc(OCC(F)(F)C(F)F)nc2)o1 +CC(C)(C)c1n[nH]c(C2CN(C(C(N)=O)c3ccccc3)CCO2)n1 +COc1ccc(N(C)S(=O)(=O)CCCCC#N)cc1Cl +COc1cc(OC)c(OC)cc1CNC(=O)Nc1ccc(F)cc1 +CC(NC(=O)NCC(C)(C)C(N)=O)c1cc2cc(Cl)ccc2o1 +Cc1cc(C)n(-c2ccc(NC(=O)c3cc(C)n(C4CC4)c3C)cn2)n1 +OCc1nc2cccnc2n1-c1ccc(C(F)(F)F)cc1 +COc1cccc(C(=O)NCCCn2nc(C)cc2C)c1F +NC(=O)c1csc(-c2nc(COc3ccccc3)no2)c1 +Cc1nc(C(=O)Nc2ccc(OCC(=O)N(C)C)cc2)c[nH]1 +CCCC1CN(C(=O)c2ccn(-c3ccc(F)cc3)n2)CCO1 +CCn1nc(-c2cccs2)cc(C(C)(C)O)c1=O +Cc1cc2nc(CN3CCN(c4ncccn4)CC3)cc(=O)n2o1 +CC(C)NC(=O)c1snc(-c2ccccn2)c1N +CC1(C)CC(NC(=O)C2(n3cnnn3)CCCCC2)CCO1 +COCCn1ccc2ncc3c(=O)n(CCO)ccc3c2c1=O +CCC(C)c1noc(C2CCN(C(=O)c3cnn(C)c3)CC2)n1 +CN(Cc1cccc(Cl)c1Cl)C(=O)c1cnn(C)c1 +CC(C)CCC(=O)Nc1ccc(NS(C)(=O)=O)cc1 +CNC(=O)c1ccc(CNC(=O)Nc2nncs2)cc1 +COCCNC(=O)CNC(=O)c1ccc(-c2ccccc2)[nH]c1=O +NC(=O)NCCCCC(=O)Nc1ccc(Cl)cc1 +Cn1cc(-c2nn(Cc3ccc(F)cc3F)c3c2CNCC3)nn1 +COc1ccccc1-c1nnc(NC(=O)c2ccn(C)n2)o1 +Nc1c(Cl)cc(S(=O)(=O)NCc2ccccn2)cc1Cl +Cc1ccccc1NC(=O)NCCc1nc(-c2cccnc2)n[nH]1 +COCCCNC(=O)C1(C)CCC(=O)N1c1cccc(C)c1C +O=S1(=O)COCCN1Cc1c(F)cccc1Cl +CCc1cc(NCCNc2ncccn2)nc(-c2ccncc2)n1 +Cc1csc(CCNC(=O)c2cccc(N)n2)n1 +CCC(CC)C(=O)Nc1cc2c(cc1N)OCO2 +COc1ccccc1Oc1ccc(CNC(=O)C2CCC2)cc1 +Cc1cc(C)n(-c2cccc(NC(=O)CCc3nc(C)no3)c2)n1 +NC(C(=O)NCc1ncc[nH]1)c1ccc(Cl)cc1 +CC(=O)c1cc(C(=O)Nc2cccc(C)c2)n(C)c1 +Cn1ncc(Cl)c1C(=O)N1CCN(CC=Cc2ccccc2)CC1 +COCCN1CCN(C(=O)c2scnc2C(C)(C)C)CC1=O +CCC(OC)C(=O)Nc1cccc(S(=O)(=O)N(C)C)c1 +CC(=O)NC1CCCN(C(=O)c2ccc(Cl)cc2O)C1 +Cn1cc(CCC(=O)N2CC(OCc3cccc4ccccc34)C2)cn1 +COc1ccc(OCC(=O)N2CC(C)Oc3ccccc32)cc1 +CC(NC(=O)c1sccc1N)c1cccc(F)c1 +CN(C)S(=O)(=O)N(C)C(CO)c1cccc(Br)c1 +CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)NCN2c1ccccc1 +CCn1c(SCc2cn3ccccc3n2)nc2cnn(C)c2c1=O +CC(C)C(=O)N(Cc1nc(-c2ccccc2)no1)C(C)C +CC(c1ccccc1)N(CC1CCC1)C(=O)c1ccoc1 +CC1CC1NC(=O)NCC1CN2CCCCC2CO1 +CC(C)N(Cc1nc2ccccc2c(=O)[nH]1)C(=O)Nc1ccccc1 +COc1ccc(OC)c(-n2c(COC(C)C)n[nH]c2=O)c1 +Cc1cc(N)cc(S(=O)(=O)N(C)Cc2ccco2)c1 +CC(=O)c1ccc(N(C)C)cc1OCc1noc(C2CC2)n1 +Cc1cc(NC(=O)CCc2ccc(OC(C)C)c(N)c2)no1 +O=C(COCC1CC2OCCN(c3ccccc3)C2C1)N1CCCC1 +CC(C)NC(=O)C1CCN(C(=O)C(C)CC2CCCC2)CC1 +CC(C)C(C(N)=O)n1cc(CCc2ccccc2)nn1 +NC(=O)CC1CCN(C(=O)CCc2nc(-c3ccncc3)no2)CC1 +CCN(C(=O)c1ccc2c(c1)NC(=O)CO2)C(C)c1ccc(F)cc1 +NC(=O)c1cc(NC(=O)c2cccc(-n3ccnn3)c2)ccc1Cl +CN(CC(O)COCc1ccccc1)C(=O)c1ccc(O)c(Cl)c1 +CC1CC(C(N)=O)c2ccccc2N1Cc1cc(C#N)ccc1F +CNC(=O)COC(=O)c1sccc1Br +Cc1ccc(C)c(C(=O)Nc2ccc(-n3ccnc3)cc2)c1 +COCCOC(=O)C1=C(C)Nc2nnnn2C1c1ccccc1C +C=CCC1CC=CC(c2ccccc2)N1C(=O)CCNC(C)=O +Cc1cc(Br)ccc1NS(=O)(=O)c1c(C)noc1C +COc1ccc(-c2nnc(COc3ccc4ncccc4c3)o2)cc1 +Nc1ccc2c(c1)C(=O)c1cc(N)c(Br)cc1-2 +COCCn1cc(NC(=O)C2CCC2)ccc1=O +CCCC(C)c1nnc(NC(=O)C(C)(C)C)s1 +NC(=O)C1(CNS(=O)(=O)Cc2ccccc2F)CCOCC1 +C=CCN(CC=C)C(=O)c1snc(-c2ccccc2)c1N +Fc1cccc2sc(NCCN3CCOCC3)nc12 +O=C(Nc1cccnc1)c1ccc(=O)n(Cc2ccc(F)cc2)c1 +OC1CCC(Nc2nc(-c3cccnc3)nc3ccccc23)CC1 +O=C(CCC1CCCC1)N1CCN(C(=O)Nc2ccccn2)CC1 +N#CCc1ccc(-c2ccccc2)n(CC2CCCO2)c1=O +COC(=O)c1cnc(NC(=O)c2cn(Cc3ccccc3)nn2)s1 +Cc1cc(NC(=O)C2CC2)sc1C(=O)N1CC2CC=CCC2C1 +O=C(OCc1cccs1)c1ccc(Cc2nc[nH]n2)cc1 +CCOC(=O)CCCNc1ncnc2sc3c(c12)CCC(C)C3 +CC(c1ccccc1)N(C)C(=O)c1ccc(Cn2cncn2)cc1 +Cc1cc(C(=O)NC2CC(C)(C)OC2(C)C)on1 +Cc1cnn(CC2CCCCN2C(=O)C2CCOC2)c1 +COc1ccc(OC(=O)c2cc3cnn(C(C)C)c3nc2C)cc1 +COc1cc(NC(=O)C(C)c2c(C)n[nH]c2C)cc(OC)c1 +CN(Cc1cc(-c2ccncc2)no1)C(=O)c1ccn(C(F)F)n1 +c1ccc2c(c1)CCN(c1ncnc3sccc13)C2 +O=C(CSc1ncccn1)N1CCN(c2ccccc2)CC1 +Cc1ccc2nc(CN3Cc4ncccc4C3=O)cn2c1 +CC(=O)NC1CCCN(C(=O)Nc2cccc(NC(=O)C3CC3)c2)C1 +COc1cccc(CSc2nccn2C2CC2)c1 +Cc1cc(C)c(CNC(=O)C2(C#N)CCCC2)c(=O)[nH]1 +COC(=O)C1(N(C)C(=O)Cc2cccc(OCC#N)c2)CCCCC1 +O=S(=O)(Cc1nc2ccccc2s1)c1nc2ccccc2[nH]1 +CC(=O)NC1CCCN(C(=O)CNC(C)c2ccc(Cl)cc2)C1 +Fc1ncccc1C1NCCc2ccc(Cl)c(F)c21 +CC(=O)c1cc(CCC(=O)N2CCc3sccc3C2C)oc1C +Cc1cc(NC(=O)CSc2nccn2-c2ccc(C)c(C)c2)[nH]n1 +Cc1ccc(C(C)NC(=O)NC(C)Cn2cncn2)cc1F +CCCC(C)C(=O)N(C)CC(=O)Nc1ccc(C)cc1 +O=C1NCC2(CCCN(C(=O)CCCc3cn[nH]c3)C2)O1 +CCOCCCn1c(=O)c(C#N)cc2c(=O)n3cccc(C)c3nc21 +CCC(C)NS(=O)(=O)c1ccc2c(c1)OCCO2 +CC(=O)Nc1ccc2c(c1)C(c1ccc(O)cc1)NCC2 +COc1cccc(-c2noc3c2CN(c2nc(C)cc(C)n2)CC3)c1 +CC(Sc1nnnn1-c1ccccc1)C(=O)NC1CCCCC1 +CCc1cc(O)n2nc(C3CCCN3C(=O)c3cccnc3)cc2n1 +COc1cc(F)c(NC(=O)c2[nH]ncc2Br)cc1OC +Cc1nn(CC(N)(C#N)c2ccccc2)c(C)c1Br +CS(=O)(=O)c1ccccc1NC(=O)NCc1cc(F)ccc1F +COc1ccc(OCC(=O)Nc2nc3ccccc3n2C)cc1 +N#Cc1ccc(OCCn2ncc3ccccc3c2=O)cc1 +CCC(CC1CCCC1)C(=O)NC(C)c1ccncc1 +O=C(Nc1ccncc1)c1ccccc1SCC(=O)N1CCCC1 +Cc1nccc(CNC(=O)NC2CC3(CCC3)Oc3ccccc32)n1 +O=c1c2ccccc2ncn1C1OC(CO)C(O)C1O +C#CCN1CCCCC1C(=O)NCc1ccccc1COC +Cc1c(CCNC(=O)c2ccc(-n3ccnn3)cc2)cnn1C +C=CCn1c(=O)c2ccccc2n2c(SCC(=O)NC)nnc12 +COC(=O)n1oc2ccc(Br)cc2c1=O +CCC1C(=O)NCCN1C(=O)c1cc(N2CCCC2=O)ccc1Cl +Cc1cc(OCC(=O)NC(C)c2ccncc2)ccc1C(C)C +Cc1ccc(NC(=O)c2cnn3c(C)cc(C)nc23)nc1 +CN(CCC(=O)NC1CC1)C(=O)C1(c2ccccc2)CCC1 +O=C(Nc1ccc(C(=O)C2CC2)cc1)c1ccc(F)c(F)c1 +CC(CN1CCCC1=O)NC(=O)c1cnc(-c2ccsc2)s1 +CCOc1ccccc1C(=O)NCc1ccccc1Cn1cccn1 +Cc1c(O)cccc1C(=O)N1CCN(CC(C)C)C(=O)C1C +FC(F)(F)c1ccnc(N(CC2CCCO2)CC2CCCO2)n1 +CCOc1ccc(CNc2cccnc2OC)cc1 +Cc1ccc(NCC(=O)Nc2cc(F)ccc2F)cc1-n1cnnn1 +C=CCn1c(N)nnc1SCc1nc(-c2ccsc2)no1 +CC(C)c1noc(-c2cnc(Nc3ccccc3)nc2)n1 +CNC(=O)CNS(=O)(=O)c1cc(C)c(C)cc1N +N#Cc1nnn(CCCc2ccccc2)c1-c1ccncc1 +CC(=O)NCCCCCC(=O)N1CC(=O)Nc2ccccc21 +O=C(NCCc1nc[nH]n1)c1cc(C2CC2)nc2ccc(F)cc12 +CNc1nn(-c2ccc(OC)cc2)c2c1C(=O)CCC2 +COc1cccc(CN2CCC(N3CC(C)OC(C)C3)CC2)c1 +COCCNC(=O)C(C)N1CCN(c2ccc(Cl)cc2)CC1 +CSc1ccc(Cl)cc1NC(=O)N(C)CCC(C)O +CC(Sc1nc2ccccc2s1)C(=O)N(C)CCC#N +Cc1cc(=O)oc(C)c1C(=O)NCc1nc(-c2ccc(F)cc2)n[nH]1 +COCC(=O)N1CCc2cc(OC)c(OC)cc2C1 +O=S(=O)(NCc1cccc(O)c1)c1ccc(Cl)cc1 +CNS(=O)(=O)c1cc(Cl)ccc1OCCOC +Cn1ncnc1CNC(=O)Nc1ccc(Cn2ccccc2=O)cc1 +COc1ccc(CC(C)OC(=O)Cn2ccc(=O)n(C)c2=O)cc1 +O=C(NCCc1ccccn1)c1cccc(N2CCCS2(=O)=O)c1 +Cn1ccnc1C(O)(CCNC(=O)Nc1nccs1)C(F)(F)F +COc1ccccc1CCc1nnc(NC(C)=O)s1 +Cc1cc(NC(=O)C(C)OCC(C)C)n(CCC#N)n1 +NS(=O)(=O)c1ccc(CNC(=O)c2cccc(F)c2)cc1 +O=C(NCC1CN2CCCCC2CO1)N1CCCC1CO +CC(O)CNC(=O)Nc1ccc(S(C)(=O)=O)nc1 +CCC1CN(CC(=O)OC)c2ccc(F)cc2N1 +CC(=O)OC(C(=O)NC1CCCCC1)c1ccc(C#N)cc1 +CCc1cccc(NC(=O)C2CCCN(c3cnn(C)c(=O)c3)C2)c1 +COC(=O)CN1CCN(C(=O)c2cn[nH]c2)CC1 +Cc1n[nH]c(C)c1CCC(=O)N1CCN2CCNC(=O)C2C1 +Cc1ccc(OCCn2nc(C#N)cc2-c2ccco2)cc1 +C#CCNC(=O)CNC(=O)C1(CCOC)CCCC1 +O=C(CNC(=O)c1ccccc1)Nc1ccc(OC(F)F)cc1 +CC(C)(C)CC(=O)Nc1ccc2c(c1)NC(=O)C(C)(C)CO2 +OCc1cccc(NCc2ccn(-c3ccc(F)cc3)n2)c1 +CC(Cc1cccc(F)c1)C(=O)NC(C)c1ccco1 +CN(CCO)c1nc2ccccc2c(=O)n1-c1ccccc1 +COC(=O)Cc1c(C)[nH]c2nc(Cc3ccccc3)nn2c1=O +COCc1csc(NC(=O)NCC2CCC(C)(C)CC2)n1 +Cc1ccc(NC(=O)N2CCOCC2C2CC2)cc1C(=O)N(C)C +CCOC(=O)Cc1c(C)c2ccc(NC(=O)OCC)cc2oc1=O +CCn1cc2c3c(cccc31)CN(C(=O)c1ccco1)CC2 +COCCNC(=O)Cc1ccc(NC(=O)Nc2ccc(F)cc2)cc1 +O=C(c1ccc[nH]1)N1CCc2nnc(Cn3cccn3)n2CC1 +CN(CC(O)C1CC1)C(=O)c1cc(Cl)c2c(c1)OCO2 +O=C(c1cn[nH]n1)N1CCN(CCOc2ccc(Cl)cc2)CC1 +COc1ccc(C(=O)CCCC(=O)N2CCCC2)c(OC)c1 +FC(F)CN1CCN(Cc2coc3ccccc23)CC1 +CC(C)Nc1ccc(C(=O)N2CCC(Oc3cccnc3)CC2)cn1 +CCOCCCC(=O)NC1CCCOc2ccccc21 +CC(C)N(C)S(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1 +CS(=O)(=O)Nc1cccc(CNC(=O)C2CCOC2)c1 +CCCCN(C)C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccc(C#N)cn2)C1 +CC(C)c1noc(CN2CCN(C(=O)c3cn[nH]n3)CC2)n1 +COc1ccccc1CCNC(=O)c1cn2cc(Cl)ccc2n1 +COc1ncccc1NCc1cc(F)c(F)cc1F +CNS(=O)(=O)c1ccc2c(c1)NC(=O)C(C(C)C)N2 +O=C(Cn1cnc(-c2cccs2)cc1=O)Nc1ccccc1Cl +Cc1ccc(OCCN(C)C(=O)c2c[nH]c3cccc(F)c23)cc1 +CCCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccncc1 +NC(=O)c1ccc(C(=O)Oc2ccccc2F)cn1 +CC(C)c1ccc(S(=O)(=O)NCc2cscn2)cc1 +CC1(C(=O)N2CCC(O)CC2)Oc2ccccc2NC1=O +CC(C)c1n[nH]c(NC(=O)c2cccc(-c3ccoc3)c2)n1 +CC1CCC(CCC(=O)NCc2csc(=O)[nH]2)O1 +Fc1cc(-c2nc3cc(Br)ccn3n2)ccn1 +Cc1ccc(NC(=O)NC(C)(C)CO)c(Cl)c1 +O=C1NCCCCC1NC(=O)C1COc2ccccc2O1 +COCCN1CCN(C(C(=O)NC2CC2)c2ccc(F)cc2)CC1C +Cc1cccc(N2CCN(CCNC(=O)c3ccnn3C)CC2)c1 +O=C(COc1ccccc1)NCc1cc(C2CC2)n(C2CCCC2)n1 +CCNC(=O)CCNS(=O)(=O)c1ccc(F)c(F)c1 +Nc1ncccc1OCc1nc(COc2ccccc2)no1 +CC(=O)NCCNC(=O)c1cn(Cc2cccc3ccccc23)nn1 +COc1ccc(C2(C(=O)Nc3cn[nH]c3)CCCC2)cc1 +CCS(=O)(=O)c1ccc(NC(=O)N(C)CC2CC2)cc1 +Cn1cc(C(=O)N2CCc3c(F)ccc(F)c3C2)c(C(C)(C)C)n1 +O=C(c1ccc(Oc2cnc3ccccc3n2)cc1)N1CCCC1 +O=C(CCOCC1CCCO1)Oc1cccc(F)c1 +O=C(NCc1nnnn1-c1cccc(F)c1)c1ccc(F)cc1 +Cc1cc(C(=O)N2CCC(C)CC2)ccc1NC(=O)c1cnns1 +Cc1nc(C)n(CCCNC(=O)C2CC(=O)N(C(C)(C)C)C2)n1 +N#Cc1cccnc1Nc1ccn(CCc2ccccn2)n1 +CC(NC(=O)OC(C)(C)C)C(=O)NC(C)c1ccccn1 +COC(=O)CC1CCCCN1C(=O)Nc1ccc(F)cc1 +CCOC(=O)Cc1csc(NC(=O)c2sc(C)nc2C)n1 +Cn1ncc2cc(NC(=O)NCC(O)CO)ccc21 +CCN1CCc2c(sc3c2c(NCC(C)O)nc2nnnn23)C1 +O=C(CCC(=O)N1CCN(c2ccc(O)cc2)CC1)c1cccs1 +CCCCN(C)C(=O)c1cc2ccccc2c(N)n1 +CSc1ccc(C(C)NC(=O)Nc2nc(C)cs2)cc1 +CN(C)S(=O)(=O)c1cccc(OC(F)(F)F)c1 +Cc1ccc(C(C)NC(=O)Nc2nnc(C(C)C)s2)s1 +C=CCOC(C)C(=O)Nc1ccc2oc(=O)ccc2c1 +Cn1c(-c2ccccc2Cl)nnc1S(=O)(=O)CCCC#N +CC(C)OCCCNC(=O)c1ccc2ccccc2c1 +COC(=O)c1cc(N2CCC(c3ccc(F)cc3)C2)ncn1 +O=C(CNC(=O)Nc1cccc(Br)c1)Nc1ccccc1 +Cc1csc(CN2CCCC(C(=O)c3ccc(F)cc3)C2)n1 +COc1ccc(C)cc1C(C)NC(=O)NCC1CCC1 +Oc1c(-n2cncn2)cnn1-c1ccc(F)cc1F +CCc1onc(C)c1NC(=O)N(C)Cc1nccs1 +CCNC(=O)c1cccnc1Nc1ccccc1OC +COCCN(Cc1cc(C#N)cs1)Cc1ccc(F)cc1Cl +COc1cc(C(C)=O)ccc1OCC(=O)Nc1c(C)n[nH]c1C +COCC(C)NS(=O)(=O)c1cc(NC(C)=O)ccc1OC +Fc1cc2ncn(CCOCC(F)(F)F)c2cc1F +CC(C)(CNC(=O)c1ccc2c(c1)OCO2)c1ccncc1 +Cc1ccc(NC(=O)NCc2ncc[nH]2)cc1NC(=O)C(C)(C)C +CCn1cc(NC(=O)N2CCc3ccccc32)cn1 +O=C(c1ccc(-n2ccnn2)cc1)N(Cc1ccco1)c1ccccn1 +NC(=O)c1oc2ccccc2c1NC(=O)c1coc2ccccc2c1=O +COc1ccccc1OCC(=O)Nc1ncccc1OC(F)F +COc1c2c(c(OC)c3ccccc13)C1C=CC2C1 +CN1CC(c2nc[nH]n2)c2cc(C(=O)NCc3cccnc3)ccc21 +CSc1nc(-c2ccccc2)nc(C)c1C(=O)N1CCOCC1 +COCCC1(C(=O)Nc2cc(F)ccc2OC)CC1 +CCCOc1ccccc1-c1cc(C(=O)N(C)C)nc(N)n1 +CCOc1ccc(C(=O)CCN2CCc3ccccc3C2)cc1N +COC(=O)NC(C)(C)C(=O)NCCc1ccc(F)cc1C +CC(=O)Nc1cccc(NC(=O)c2cn(CC(C)C)c3ccccc23)c1 +CCOC(=O)c1ccsc1NC(=O)c1cc(C)nn1C(C)C +O=C(NCC1CCCO1)c1cc2c(s1)CCCC2 +CC1COCCN1CC(O)COCc1ccccc1 +CC(C(=O)NC1CCCC1)S(=O)(=O)c1nc2ccccc2[nH]1 +Nc1cc(-c2csc(-c3nc[nH]n3)n2)ccc1F +OCCCn1nc(CO)cc1-c1ccc2c(c1)CCC2 +O=S(=O)(N1CCCCC1)N1CCC(Cc2cccc(F)c2)CC1 +O=C(Nc1ccc(NC(=O)c2ccco2)nc1)c1cnccn1 +COc1cccc(-c2cc(C(=O)N3CCCCCC3)no2)c1 +Cc1ccc(NS(=O)(=O)c2ccc(S(N)(=O)=O)cc2)c(C)c1 +O=C(CS(=O)(=O)c1ccccc1)Nc1nnc(-c2ccccn2)o1 +CC(C)c1csc(-c2ccc(OCC(N)=O)c(N)c2)n1 +Cc1cccc(C)c1NC(=O)CNC(=O)c1c[nH]c2cccc(F)c12 +O=C(CSc1ccccc1)N1CCN(C(=O)c2ccoc2)CC1 +O=C(CSc1nncc(=O)[nH]1)NCc1ccc(Cl)cc1 +O=C(Nc1ccccc1F)C1COc2ccc(F)cc2C1 +C=CCn1c(C)cc(-c2csc(NC(=O)c3ccco3)n2)c1C +CCOc1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1OC +Cc1ccc2c(c1)S(=O)(=O)c1ccccc1C(=O)N2 +CC=CCOC(=O)CCc1nnc(-c2ccc(C)cc2)o1 +Cc1ccc(C#N)c(=O)n1-c1ccc(C(C)C)cc1 +COc1cc2ncn(Cc3ccc(C)s3)c(=O)c2cc1OC +CC(C)(C)CC(C)(C)NC(=O)c1cccc(S(C)(=O)=O)c1 +CC(C)c1ccc(C(=O)N2CCN(CCC#N)CC2)cc1 +c1cnc2ccc(NCCN3CCOCC3)cc2c1 +COc1ccc(C(=O)Nc2cc(C)cc(C)c2)c(N)c1 +CCCCC(=O)OCc1cc(=O)n2oc(C)cc2n1 +CCc1noc(C(C(C)CC)N2Cc3ccccc3C2=O)n1 +Cc1cc(CN(C)C(=O)Nc2ccccc2C(C)C)no1 +Cc1nc2ccccc2n1CC(=O)N(C)CC(C)C#N +Fc1cc2c(Cl)c3c(nc2c(F)c1F)CCC3 +COc1cccc(CN2CCN3C(=O)N(C4CCOCC4)CC3C2)c1 +COc1ccccc1NC(=O)c1sc(-n2cccc2)nc1C +CC(=O)Nc1cccc(NC(=O)C(C)Sc2ccccc2)c1 +CC(=O)c1c[nH]c(C(=O)NCCc2nc3c(s2)CCCC3)c1 +COc1cccc(CN2CCN(C(=O)Nc3ccccc3)CC2)c1 +O=C(Cc1ccc(O)c(Cl)c1)N1CCN(CCn2cncn2)CC1 +CC(=O)Nc1ccc(NC(=O)Cc2ccc(C)cc2C)cc1 +NC(=O)C1CCN(c2ccc(S(=O)(=O)N3CCOCC3)cn2)C1 +O=C(NCc1ccco1)C1CCN(C2=NC=NC3=NC=NC32)CC1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1C(N)=O +COc1ccc(-c2noc(-c3cc(=O)[nH]c(=O)[nH]3)n2)cc1 +CC(=O)c1cc(C(=O)Nc2cnccc2Oc2ccccc2)n(C)c1 +CC(NC(=O)c1ccc(C(N)=O)cc1)c1ccc(-n2cncn2)cc1 +CC1CC(C)CN(S(=O)(=O)N2CCC(CO)CC2)C1 +CCC(CC)NS(=O)(=O)c1ccc(N2CC(C)OC(C)C2)nc1 +COc1ccc(C(=O)c2c[nH]c(C(=O)NCC3CCCO3)c2)cc1 +Cc1c(C(=O)NC2CCCOC2)oc2c(C)cccc12 +O=C(NCc1cscn1)NC1CC1c1cccc(Cl)c1 +O=C(Cn1cc(Br)ccc1=O)Nc1cccc(Cl)c1 +COc1ccc(-c2nsc(NC(=O)COc3ccccc3)n2)cc1 +CC(=O)Nc1cc(NC(=O)NCCc2ccnn2C)ccc1Cl +CC(C)(C)n1nccc1C(=O)Nc1cccc(F)c1 +Cc1cccc(C(=O)N2CCC(C(=O)c3cccs3)CC2)c1 +COC(=O)COc1cccc(NC(=O)c2ccccc2)c1 +Cc1nc(CN(C)C(=O)Cn2cccnc2=O)cs1 +COc1ccc(CNCc2nc(-c3ccccc3)cs2)cc1OC +CN(C)C(=O)CCNC(=O)NC1CCCCC1C(C)(C)C +CNC(=O)Cn1nnc(CO)c1COc1ccccc1 +NC(=O)c1ccc(NC(=O)N2CCCC(CO)C2)cc1Cl +Clc1ccccc1-c1nc(-c2ccc(-n3ccnc3)nc2)no1 +Nc1ccc(C(=O)NC2CCCC(O)C2)cc1F +NC(=O)c1ccc(C2CCCN2C(=O)CSc2ccccc2)s1 +Cc1nc2ccccc2n1S(=O)(=O)N1CCCCCC1 +CCN1C(=O)C(O)(C2COC(C)(C)CC2=O)c2ccccc21 +CC(C)(O)C1NCCc2ccc(F)c(Br)c21 +Cc1nc(N2CCN(Cc3ncccc3C)CC2)c2c(C)noc2n1 +CCC(C)CS(=O)(=O)NCc1nnc2ccccn12 +c1cnc(OCc2nnc3n2CCN(CC2CCOCC2)C3)nc1 +O=C(Nc1ccc(OC(F)F)c(F)c1)N1CCCC(O)C1 +CCc1onc(C)c1NC(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C +CCS(=O)(=O)c1ccc(NC(=O)c2ccccn2)cc1 +CCCCC(=O)N1C2CCC1CC(S(=O)(=O)c1ccccc1)C2 +CCn1nc(C)cc1C(=O)Nc1nnc(-c2cc(C)no2)o1 +CCN(CC)C(=O)CN(c1cccc(C)c1C)S(C)(=O)=O +CCC(CC)NC(=O)CSc1nnnn1-c1cccc(F)c1 +Cc1ccc(C(=O)N(C)Cc2ccc(O)cc2)s1 +O=c1[nH]c(CNc2ccc(Cl)cc2)nn1Cc1ccc(Cl)cc1 +CCC(C)Nc1nnc(-c2sc(C3CC3)nc2C)s1 +CCc1nc(SCc2cc(O)n[nH]2)c2oc3ccccc3c2n1 +CC(Oc1ccccc1C#N)C(=O)c1c[nH]c2ccccc12 +CN(Cc1ccccc1Cl)S(=O)(=O)c1cccc(N)c1 +CC(C)(C)n1cc(C(=O)N2CCCS2(=O)=O)cn1 +CCc1nc2nnc3c(=O)n(CC(C)C)ccc3n2n1 +Nn1c(SCC(=O)NCC2CCCO2)nnc1-c1cccs1 +Cn1c(SCC(=O)NC2CCCCC2)nc2c(c1=O)SCC2 +COc1cc(OC)c(C(=O)COc2ccccc2N)cc1OC +N#Cc1ncn(Cc2csc(-c3ccccc3F)n2)c1C#N +O=C(Cc1ccc2c(c1)CCCC2)NCCC(=O)N1CCCC1 +O=C(COc1ccc(F)cc1)N1CCOc2ccccc21 +CCc1cccc(C)c1NCCCN1CCOCC1 +NS(=O)(=O)N1CCN(Cc2cnn(-c3ccccc3)c2)CC1 +CN(C)C(=O)CN(C)C(=O)c1cc(C2CC2)nc2ccccc12 +Cc1cc2nccc(C3CCCCN3C(=O)c3cnccn3)n2n1 +COC(=O)c1ccc(NC(=O)C(OC)c2ccccc2)cc1 +Cc1nc2ccc(NC(=O)NCCCOCC(C)C)cc2s1 +COCCNC(=O)CCn1c(=O)c(C)nc2cc(C)c(C)cc21 +COC(=O)C(O)c1ccc(OC)c(C(C)(C)C)c1 +N#Cc1cccc(C(=O)NCc2cc3ccccn3n2)c1 +O=C(NCCCO)Nc1ccc(Cl)cc1OCC(F)(F)F +CCC(=O)Nc1ccc(NCc2cnn(C)c2)cc1 +Nc1c(NCc2ccc3c(c2)OCO3)ncnc1Nc1cccnc1 +O=C(CN1CCN(CC(O)c2ccccc2)CC1)Nc1cccnc1 +CCOc1ccc2cc3c(nc2c1)OC(=O)N(CC1CC1)C3 +COC(=O)C(C)NC(=O)c1sccc1-n1cnnn1 +N#CCc1nc(Cc2ccc(Cl)c(Cl)c2)no1 +Cc1ccc(-c2ncco2)cc1NC(=O)C1OCCC1C +Cc1noc(C)c1C(=O)NC1CCN(c2ccc(F)cc2F)C1 +CC1CCCC(CNC(=O)c2ccc(N(C)C)nc2)C1 +Cc1cc(C(=O)NCc2c(F)cccc2OC(F)F)no1 +COC(=O)c1ccc(F)c(NCc2noc(C(C)C)n2)c1 +CCOC(=O)CC1c2ccccc2CCN1C(C)=O +O=C(CCCNC(=O)c1ccsc1)Nc1cccc2c1CCCC2 +Cc1cccc(NC(=O)Nc2ccc(F)c(Cl)c2)n1 +O=C(N=c1[nH]nc2ccccn12)C1(c2ccc(F)cc2)CC1 +Cc1cc(OCC(=O)NCc2cccnc2)ccc1Br +CN1C(=O)C(C)(C)c2cc(S(=O)(=O)NCC3CCCO3)ccc21 +CCOC(=O)c1oc2ccccc2c1NC(=O)c1ccc(C#N)cc1 +O=C(CCC1CCCCC1)Nc1ccc(NCCO)nc1 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+CC1N2CC3(C)CN1CC(c1ccccc1)(C2)C3O +CN(Cc1cnn(-c2ccccc2)c1)S(=O)(=O)N(C)C1CCCC1 +Cc1cc(N2CCN(C(=O)c3ccccc3)CC2)nc(C(C)C)n1 +COc1cccc(CNC(=O)NCC(C)Oc2ccccc2)n1 +COc1ccc(C=c2sc3n(c2=O)CCN=3)c(OC)c1OC +Cn1c(N)c(C(=O)CSc2nnc3ccccn23)c(=O)n(C)c1=O +CC(=O)Nc1ccccc1OC(=O)NC(C)(C)C +COCc1cc(CC2CC(NC(=O)N3CCOCC3)C2(C)C)no1 +Oc1cc(F)ccc1-c1ccc(-n2cccn2)cc1 +CC(=O)c1cc(Br)ccc1OCCn1cccn1 +Cc1cc(C(=O)CSc2ncccn2)c(C)n1Cc1cccs1 +Cc1nn(C)c(C)c1NC(=O)CNc1cccc(Cl)c1F +CCc1cccc(C)c1NC(=O)CN1C(=O)CCn2nc(C)cc21 +C=CCNC(=O)NCCc1ccc(OC)c(S(N)(=O)=O)c1 +NC(=O)c1cc(NCc2ccc(Br)cc2)ccc1F +COc1ccc(-n2nc(C(N)=O)c(=O)cc2OC)cc1 +Fc1ccc(CN2CCOC(C3CCCO3)C2)c(Cl)c1 +Cc1cccc(CCNC(=O)CN(C)C(=O)OC(C)(C)C)c1 +CNC(=O)c1cccc(NC(=O)Cc2cccc(OC(F)F)c2)c1C +NC(=O)C1CCCCN1C(=O)c1ccc(OCC(F)F)nc1 +Cc1ccccc1C1CC1C(=O)Nc1ccccn1 +COCCOCCNC(=O)c1n[nH]c2ccccc12 +CN(C)C(=O)c1cc(NC(=O)Nc2cnn(C)c2)ccn1 +Nc1cccc(CC(=O)Nc2ccc(Cl)cc2Cl)c1 +Cc1c(NC(=O)NCCc2ccccn2)cccc1OC(F)F +COC(=O)Cn1ncc2c(N3CCCC3c3ccsc3)ncnc21 +CN(CC(=O)Nc1ccc2c(c1)OCO2)c1ccc(F)c(F)c1 +CC(C)C(=O)N1CCC(CN2CCCCC2=O)CC1 +O=C(NCc1cccnc1)c1cccc2c1OCCCO2 +Cc1nn(C)c(C)c1-c1cc(C(=O)NCCC(=O)NC(C)C)[nH]n1 +COCC(C)OC(=O)c1cc(Cl)c(N)cc1OC +CCOc1cccc(NC(=O)NCC(=O)Nc2c(C)cccc2C)c1 +O=C(NCc1ccc(-c2ccn[nH]2)cc1)c1cccnc1-n1cncn1 +O=C(Cn1nc2ccccn2c1=O)Oc1ccccc1F +COc1ccccc1NC(=O)c1ccc(C(N)=O)cc1 +CN(C)S(=O)(=O)c1ccc(CN2CCc3ccccc32)o1 +CCN(C(=O)c1ccc2c(c1)OCCCO2)C1CC1 +COc1ccc(NC(=O)COC(=O)c2ccccn2)cc1 +CC1CN(C(=O)C2CCN(c3ccc(C#N)cc3F)CC2)CC(C)O1 +CCCCCOc1ccc2c(c1)CCNC2c1ccnnc1 +Cc1ccc(S(=O)(=O)NCc2ccc(S(C)(=O)=O)cc2)cc1 +CC1(C)CC(=O)Nc2cc(C(=O)C3CC3)ccc2O1 +C#CCOc1cccc(C2NC(=O)NC(C)=C2C(=O)OCC)c1 +NC(=O)C1CN(C(=O)NCCCn2ccc3ccccc32)CCO1 +CCOc1ccc(CC(=O)NCC2(O)CCCC2)cc1 +CCS(=O)(=O)NCCCNC(=O)c1cnc2[nH]nc(C)c2c1 +Cc1cc2c(=O)n(CCOCC3CCCO3)cnc2s1 +CCc1c(C(=O)NC(C)Cc2ccccc2F)[nH]c(C)c1C(C)=O +CCOc1ccc(Cl)c2c1CCNC2CNC +NC(=O)C1CCN(C(=O)Cc2cccc(C(F)(F)F)c2)C1 +Cc1cc(C)n2c(CNc3cc(C)on3)cnc2n1 +O=C(COC(=O)Cc1noc2ccccc12)NCc1cccs1 +Cc1cc2n(n1)CCC(=O)N2CC(=O)N1CCCCCC1 +CCCOc1ccc(CNc2c[nH]ccc2=O)cc1 +CCCC1CN(C(=O)c2c(C)nn(-c3ccc(F)cc3)c2C)CCO1 +Cc1cccc(Cl)c1NC(=O)CSc1nncs1 +CCc1ccc(C(=O)N2CCN(c3ncccc3C#N)CC2)cc1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)Cn1ccc2ccccc21 +O=C(NCCOCC(F)(F)F)NCc1nnc2ccccn12 +CNS(=O)(=O)c1ccc(C(=O)N(C)CCc2ccccc2)cc1 +NC(=O)C(OC(=O)c1ccc(S(N)(=O)=O)cc1)c1ccccc1 +CN(CC1CCN(c2ccccc2)C1)C(=O)c1cn2ccsc2n1 +Cc1ccc(NC(=O)CCNC(=O)c2ccco2)cc1C +Cc1ccc(S(=O)(=O)Nc2ccc(N)cc2Br)s1 +Cc1ccc(C(=O)NCCNS(=O)(=O)N(C)C)cc1F +O=C(c1ccccn1)N1CC2COCC2(COCC2CC2)C1 +Cc1cnn(CC2CN(Cc3cc(Cl)c4c(c3)OCO4)CCO2)c1 +CC(C)N(C(=O)Cn1nnc(-c2ccccc2)n1)C(C)C +COC(=O)c1cccc(OS(=O)(=O)c2ccc(C(N)=O)cc2)c1 +CN(CCCC1CCCO1)C(=O)c1ccc2cccc(F)c2n1 +N#Cc1nnn(Cc2cccc(Cl)c2)c1C1CCC1 +COc1ccc(CNC(=O)c2cccnc2)cc1OC +CCOc1ccc(NC(=O)c2cncc3ccccc23)cc1CO +CC(CC(=O)N(C)CCC(F)(F)F)NC(=O)c1ccccc1 +CCNc1ccc(Cl)cc1NC(=O)CSc1nncs1 +O=C(Nc1ccc(-c2nc3ccccc3o2)c(O)c1)c1cccnc1 +CC1CCCN(C(=O)c2onc(-c3ccccc3)c2N)C1 +CC(C)(C)c1nnc(CNc2ccc3c(c2)C(=O)CCC3)o1 +Cc1noc(CCCC(=O)N2CCN(c3cnccn3)CC2)n1 +COc1ccc(Cn2ccc3c(c(C)nc4nc(C)nn43)c2=O)cc1 +NC(=O)c1ccc(C(=O)OCCc2c[nH]nc2C(F)(F)F)cc1 +Cc1ccc(C(=O)OCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1 +Cc1n[nH]c(C)c1NC(=O)CSc1nnc(-c2ccccc2)o1 +Cc1ccc(OCCNC(=O)COc2ccccc2)cc1 +N#Cc1cccn(-c2ccccc2Br)c1=O +CC(C)c1nc2ccc(F)cc2n1CCN1CCOCC1 +Cc1ccc(CN(C)C(=O)c2ccc(S(=O)(=O)N(C)C)cc2)o1 +CC(C)(C)NC(=O)N1CCN(c2cc(C(F)(F)F)ccn2)CC1 +CCNC(=O)C1CCCN(C(=O)Nc2scnc2C2CC2)C1 +COc1ccc(C(C)N2CCOC(Cn3cccn3)C2)cc1Cl +c1ccc2c(c1)oc1c(NC3CCCC3)ncnc12 +O=C(CCc1cccc(F)c1F)N1CCC(O)(C(F)(F)F)CC1 +CCc1cc2c(=O)n(CC(=O)Nc3cc(F)ccc3F)cnc2s1 +COc1ccc(CN2CCn3cnnc3C2)c(Cl)c1OC +Cc1cc(N2CCOCC2)nc(C2CCN(C(=O)C(C)(C)C)CC2)n1 +C=CCNS(=O)(=O)c1cccc(C(=O)Nc2ccc(OC)cc2)c1 +CCc1nc(C)ncc1C(=O)N1CCCC(c2cc(C(N)=O)[nH]n2)C1 +Cn1c(C(=O)NC2CCCC2)cc2c(=O)oc3ccccc3c21 +CC(O)CN(Cc1nnc(-c2ccccc2)o1)c1ccccc1 +O=C(CCNC(=O)c1ccc(F)cc1Cl)Nc1cn[nH]c1 +CNC(=O)C1CCN(C(=O)Cc2ccc(F)cc2)CC1 +Cc1cccc(C(C)C)c1NC(=O)Cn1cc(Br)cn1 +COc1cccc(C(=O)NCC(=O)Nc2cccnc2)c1F +CCN(CC)C(=O)CNc1ccc(C(=O)NC2CCCC2)cc1C +O=C(Nc1cccc(-n2cccn2)c1)N1CCCC(C(F)(F)F)C1 +CC(C(=O)N(C)c1ccccc1)N1CCN(c2ccccc2)CC1 +CC(C)CNS(=O)(=O)c1cccc(C(=O)N(C)c2ccccc2)c1 +Nc1cccc(N2CCN(C(=O)CCc3ccco3)CC2)c1 +CCOc1ccc(N(CC(=O)NC)S(C)(=O)=O)cc1 +O=C(NCCNC(=O)C1CC1)c1ccc(Cl)cc1 +COc1ccc(-c2nn(C(C)C)c3c2C(=O)CCC3)cc1 +COc1cc(CC(=O)c2ccc3c(c2)OCO3)cc(OC)c1OC +NC(=O)c1cn(Cc2ccccc2Cl)c(C2CC2)n1 +CC(C)CC(=O)c1ccc(S(=O)(=O)N(C)CCO)cc1 +CC(c1ccc(O)cc1)N(C)C(=O)Nc1ccccc1F +CN(Cc1cc(Cl)cc(Cl)c1)Cc1noc(C2CC2)n1 +Cc1ccc2ncc(C(=O)N(C)CC(C)(C)O)n2c1 +Nc1cc(CCC(=O)NCc2ccco2)ccc1N1CCCC1 +Cc1ccc(CN(C(=O)NC2CC2)C(C)C)s1 +COc1ccc(C(C)NC(=O)c2ccccc2C)cc1OC +c1coc(-c2nccn2CCc2c[nH]c3ccccc23)c1 +COCC(C)NC(=O)C1CC(=O)N(c2ccccc2C)C1 +CC(C)C(NC(N)=O)C(=O)NCc1cccc(Cn2cccn2)c1 +CC(C)N(CCO)C(=O)c1cccc2c1NCCC2 +CCc1nnc(CN2CCN(C(C)c3nc(C)no3)CC2)o1 +Cn1cnnc1SCc1cccc2ccccc12 +N#Cc1ccc(NC(=O)Cn2cc(C(F)(F)F)ccc2=O)cc1 +CCc1cc(C2CCCN2C(=O)Nc2ccc(OC)cc2OC)on1 +O=C(NCCNc1cc(=O)oc2ccccc12)c1cnccn1 +COc1ccc(C2CCN(C(=O)c3cccc(OC)c3F)C2)cc1 +COC(=O)C1=C(CN2CCCC2)NC(=O)NC1c1ccccc1Cl +Cc1nc(C)c(C(=O)N(C)CC(=O)NC(C)C)s1 +CC(NC(=O)N(C)Cc1cnn(C)c1)c1nncn1C +Cc1noc(C)c1CCCNC(=O)NC1c2ccccc2CC1C +O=C(CNC(=O)c1ccsc1)Nc1cccc2cnccc12 +N#Cc1cccc(CNCC(C(=O)N2CCOCC2)c2ccccc2)c1 +CC(NC(=O)COc1cccc(N2CCCC2=O)c1)c1ccccc1 +CC(C)(NC(=O)NCC(F)(F)F)c1ccccc1 +Cc1ccc(C)c(CC(=O)Nc2ccnc(C)c2)c1 +Cn1nc(CC(C)(C)C)cc1NC(=O)c1ccc2[nH]nnc2c1 +CC(C)C(=O)Nc1ccc(NC(=O)c2cccnc2)cc1 +Cc1ccccc1N1CC(C)N(C(=O)CCc2cnn(C)c2)CC1=O +CCc1nnc(-c2cccnc2N2CCN(C(=O)CC(C)C)CC2)o1 +CC(=O)c1cccc(Nc2ncnc(NCC3CCCO3)c2N)c1 +O=C1CCN(C(=O)CSc2ccccc2)CCN1 +Cc1ccc(C)c(CC(=O)N2CCCN(C(N)=O)CC2)c1 +CC(CNC(=O)CSc1nncn1C(C)C)N1CCOCC1 +Cn1cc(C(=O)N2CCCCCC2)cc(NC(=O)CC(C)(C)C)c1=O +CN(C)C(=O)c1ccc(C(=O)N2CCCCc3ccccc32)cc1 +CN(C(=O)c1cccc(F)c1)C(C#N)c1cccnc1 +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2ccccc2OC)c1C +Cc1cccc(C(C)CNCc2ccc(S(C)=O)cc2)c1 +CC1(COC(=O)Cc2c(F)cccc2F)COC1 +COc1cccc(SCC(=O)N2CCC3(C2)OCCO3)c1 +CC(=O)Nc1sc(C)c(C)c1C(=O)OCc1cc(C#N)ccc1F +COC(=O)N1CCC(NC(=O)c2cc(C)cc(C)c2)CC1 +CCOC(=O)C(N)Cc1c(F)ccc2cnn(C)c12 +COc1ccc(N2CCn3c(SCC#N)nnc32)cc1 +CC(=O)c1nn(-c2ccc(F)cc2)cc1C(=O)c1ccccc1 +Cc1ocnc1CNC(=O)Nc1ccccc1Oc1ccccc1 +CCCOc1ccc(CNc2ccc3[nH]nc(C(N)=O)c3c2)cc1 +Cc1ccc(=O)n(CC(=O)Nc2cc(Cl)cc(Cl)c2)n1 +O=C(c1ccc(C(F)(F)F)cc1)N(CCO)CCO +O=C(NCc1nc2ccccc2s1)c1c[nH]nn1 +CC(=O)Nc1nc(C(=O)N(C)c2ccccc2)cs1 +COc1cc2c(cc1OC)-c1c(c(C(=O)NC(C)(C)C)nn1C)C2 +O=C(NCc1csc(=O)[nH]1)c1cc(-c2ccncc2)on1 +CC(O)CCc1ccc(OCC2CCOC2)cc1 +N#Cc1ccccc1Cn1c(CCO)nc2cccc(F)c21 +Cc1cc(F)c2c(c1)CCCN2CC(=O)N(CCC#N)CCC#N +Nc1cc(C(F)(F)F)ccc1NC(=O)c1ccccc1F +CCN(CC)c1ncc(CN2CCOC3(CCCC3)C2)s1 +Cc1noc(C2COCCN2CCc2ccc3c(c2)CCO3)n1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)NCC(F)(F)F +CCn1nc(C)cc1C(=O)NCC(=O)NCC(=O)NC +COc1ccc(F)cc1C(=O)NCc1nc(C)cs1 +COc1ccc(CNC(=O)NCC(O)(c2ccco2)C2CC2)cc1 +COc1nn(C)c2c1CCCN(C(=O)Cc1ccc(C)cc1)C2 +CC(NC(N)=O)C(=O)NC(C)c1ccc(Oc2ccccc2)cc1 +O=C(NCCc1cc(Cl)cc(Cl)c1)Nc1ccncc1 +Nn1c(SC2CCCCNC2=O)nnc1C1CCCCC1 +CC(=O)c1cc(CCC(=O)OCc2ccc(C#N)cc2)oc1C +COc1ccc(Cc2nc(C(C)N)cc(=O)[nH]2)cc1OC +CC(=O)c1nc2ccc(F)cc2n1Cc1cccnc1 +CCc1ccccc1NC(=O)c1cccc(CN2CCCC2=O)c1 +Cc1cc(C)nc(Nc2ccc(C(=O)NCCO)cc2)n1 +O=C(NC1CCC(C(F)(F)F)CC1)c1scnc1C1CC1 +O=C(COc1cc(C(F)(F)F)cc(C(F)(F)F)c1)NC1CC1 +CCOC(=O)c1c(-c2ccc(OC)c(OC)c2)noc1N +CCOC(=O)c1sc(-c2ccc(N)cc2)nc1C(F)(F)F +Cc1ccc(C(=O)N(C2CC2)C(C)c2ccccc2Cl)c(=O)[nH]1 +Cc1cccc(N2CCN(C(=O)c3ccc(F)cc3)CC2)c1 +Cn1cc(NC(=O)c2csc(COc3ccc(Cl)cc3)n2)cn1 +COc1ccc(Cl)cc1NC(=O)c1cccc(C#N)c1 +COc1ccc2c(C(=O)NCCn3nc(C)cc3C)cc(=O)oc2c1 +CCSc1nnc(N2CCOCC2)n1Cc1ccccc1 +COc1cccc(C(=O)N(C)CCN(C)c2ccccc2)c1F +CC(C)Oc1ccc(NC(=O)CN2CCCCC2=O)cc1Cl +Cc1nc(C)c(C(=O)Oc2cccc(NC(=O)C3CC3)c2)s1 +Cc1noc(C(C)Sc2nccn2-c2ccccc2)n1 +COc1cccc(CNC(=O)CSc2ccc(C)cc2)c1 +COc1ccccc1CCNC(=O)c1ccc2cc[nH]c2c1 +COc1cccc(C(=O)Nc2ccccc2C(=O)NCC(C)C)c1F +N#Cc1c(NC(=O)Cn2ccc(C(F)(F)F)n2)sc2c1CCC2 +Cc1cc(C)cc(NC(=O)CNc2cccc(C(N)=O)c2C)c1 +CCC(=O)Nc1ccc(NC(=O)c2cnc3[nH]nc(C)c3c2)cc1 +Clc1ccc(COc2ccc(CNc3ncn[nH]3)cc2)cc1 +COc1nn(C)cc1C(=O)Nc1ccc(CC(N)=O)cc1 +Cc1ccccc1NC(=O)c1cc(-c2ccncc2)[nH]n1 +CNC(=O)c1ccc(Cl)c(NC(=O)Cc2cn3ccsc3n2)c1 +COc1ccc(CNC(=O)c2csc3cncn23)cc1OC +COc1ccccc1CNC(=O)c1ncccc1O +CC(C)N(Cc1ccccc1)C(=O)c1ccnc(F)c1 +CC1(C)CN(C(=O)CCNS(C)(=O)=O)CC1(C)O +O=C(Nc1ccc(-n2nccn2)cc1)c1ccnc(OC2CCC2)c1 +CCOC(=O)C(C)NC(=O)c1c(CC)noc1C +COc1ccccc1NC(=O)c1nn(-c2ccccc2)c2c1COC2 +CS(=O)(=O)NCCCNC(=O)c1ccc2cc[nH]c2c1 +O=C1CCc2ccc(C(=O)NCc3ccncc3)nc2N1 +COC(=O)C(O)(CC(=O)Nc1ccc(F)cc1)C(F)(F)F +COc1ccccc1C(=O)NCC(=O)NCc1ccc(C)c(F)c1 +COc1ccnc(N2CCN(C(=O)c3csc(C(C)C)n3)CC2)n1 +Cn1cnnc1SCCNC(=O)c1cc2n(n1)CCCO2 +NC(=O)c1c(NC(=O)NC2CCCCC2)sc2c1CCC2 +CCCn1c(C(O)c2ccc3c(c2)OCO3)nc2ccccc21 +O=c1[nH]c(C2CCCCC2)nc2ccc(N3CCCC3)cc12 +Cc1cc(NCC(=O)N2CC(C)OC(C)C2)ccc1Br +CN(CC(=O)N1CCOCC1)C(=O)CCCc1c[nH]c2ccccc12 +O=C(CCCOc1ccccc1Br)NCC(F)(F)F +N#Cc1cc(-c2ccc3c(c2)OCCO3)oc1C(F)(F)F +OC(CNc1ccccc1F)c1cccc(Cl)c1 +CCc1nnc(NC(=O)N2CCN(c3ccccc3OC)CC2)s1 +COc1ccc(-c2cc(C#N)nn2CC(C)C)c(OC)c1 +CCCC(=O)N1CCCC1C(=O)Nc1cccc2c1CCCC2 +CC(NC(=O)CSc1nncn1C1CC1)C(=O)N1CCCCC1 +COc1cccc(C(=O)Nc2ccc(-n3cncn3)cc2)c1 +O=S(=O)(CCCc1cn[nH]c1)c1ccc(Cl)c(Cl)c1 +Cc1cc(C(=O)Nc2ccc(Cl)cn2)c(C)o1 +Cc1csc(NC(=O)c2cc(Br)cn2C(C)C)n1 +Cc1cc(C(=O)NC(c2ncnn2C)C(C)C)c2cccc(C)c2n1 +COc1ccc(C(N)=O)cc1NC(=O)c1ccc(-c2ccccc2)n1C +COc1cc(-c2nc(-c3ccccn3)no2)cc(OC)c1OC +CC(Sc1nnnn1C)c1nc(C2CC2)no1 +COC(=O)NCC(=O)NC(c1cccs1)C(C)C +Cc1ccc(OCc2cc(C(=O)N3CCCCC3CO)no2)cn1 +COCC(NC(=O)Nc1ccncc1F)c1ccccc1 +CCOC(=O)CNc1ncc(Br)c2c(F)cccc12 +O=C(Nc1cc(CCc2ccccc2)n[nH]1)c1cnccn1 +C=CCc1ccc(OC(=O)c2cccn2C)c(OC)c1 +N#Cc1cccc(NC(=O)COC(=O)CCC2CCCC2)c1 +O=c1ccc(CNCc2c(F)cccc2Cl)c[nH]1 +CCOc1cccc2n[nH]c(=NC(=O)c3ccccc3)n12 +O=C1c2ccccc2NC(c2cc[nH]n2)N1Cc1ccc2c(c1)OCO2 +CC(=O)Nc1cccc(CN(CCC(N)=O)c2cccc(C)c2)c1 +COc1ccc(C(C)N(C)C(=O)c2cccc(C)c2)cc1 +COC1CCCN(S(=O)(=O)c2ccc(F)c(C)c2)C1 +CCOC(=O)C1=C(CNc2ccc(Cl)c(C#N)c2)NC(=O)NC1 +O=c1nc(NCCc2ccccc2)[nH]nc1-c1ccc(F)cc1 +COc1cccc(CNC(=O)Cn2ncc3c2-c2ccccc2OC3)c1 +Cn1nnnc1SCc1cc(O)n(-c2nc3ccccc3s2)n1 +Cc1cc(NC(=O)NCCc2cccs2)n(C)n1 +Cc1cc(-c2nnc(CCC(=O)NCc3ccc(C)o3)o2)n(C)n1 +COc1ccc(S(=O)(=O)N(C)c2ccc(Cl)cn2)cc1 +C=CCNC(=O)NCC1(c2ccccc2C)CCOCC1 +COC(=O)C(N)c1cc(Br)c2c(c1)OCCO2 +CSc1cc(C(=O)Nc2cc(NC(=O)C(C)C)ccc2C)ccn1 +CSc1ccc(Cl)cc1NC(=O)C(C)Sc1nncs1 +COc1cc(Br)cc(C)c1NC(=O)c1cc(C)n[nH]1 +Cc1nc(-c2ccc(F)c(F)c2)sc1C(=O)NCc1ccnn1C +COCc1cc(C(=O)Nc2ccc(C(C)(C)C)nn2)ccc1F +CC1CN(c2ncnc3c2cnn3C)CC(C)(C)O1 +COc1ccccc1CCC(=O)N1CCCC1c1cc(C)on1 +Cc1ccc(C(=O)NCCc2cn(C)c3ncccc23)c(C)c1 +CCCNc1ncc(Br)cc1C(=O)N(C)C(C)CC +CC(C)Oc1cccc(C(O)CNC(=O)c2cccc(Cl)c2)c1 +CC(C)C(Sc1nncn1C)C(=O)Nc1ccccc1F +Cc1cc(NC(=O)c2cnccn2)n(-c2cccc(C(F)(F)F)c2)n1 +CCC(O)c1ccccc1OCC(=O)NCC1CC1 +O=C(NCC#CCOc1ccc(F)cc1F)c1ccc(=O)[nH]c1 +CCS(=O)(=O)N(C)c1ccc(C(=O)Nc2ccc(OC)cc2)cc1 +Cc1cccnc1Nc1ncnc(NCc2ccco2)c1N +O=C(NCc1ccc(Cn2cncn2)cc1)N1CCc2ccccc2C1 +CC(C)(C)OC(=O)NCC1CCC(C(=O)Nc2nccs2)CC1 +Nc1cc(NC(=O)Nc2cccc(F)c2)ccc1F +N#CC(c1ccccc1)N1CCN(c2ccc(F)cc2)CC1 +O=C(Cc1cccc(Cl)c1)N1CCOCC1C1CC1 +COc1cc(CNc2nc3ccccc3s2)ccn1 +O=C(NCC#CCOc1ccccc1Cl)c1cc(C2CC2)on1 +COC(=O)C(O)C(NC(=O)OC(C)(C)C)c1cccc(N)c1 +O=C(CCC1CCCCC1)NCCc1nnc2ccccn12 +CC(NC(=O)c1cc(Br)cs1)C1CCCO1 +CC(O)CNC(=O)c1ccc(C(=O)NCC(C)O)cc1 +Cc1ccc(-n2cc(SC(=O)N(C)C)cn2)cc1 +CCC(Oc1ccccc1)C(=O)Nc1cccc(N)c1 +O=C(NCCO)C1CC(=O)N(c2ccc(Cl)cc2)C1 +CN1CC(O)N(c2nnc(C(F)(F)F)s2)C1=O +N#Cc1ccc(O)c(NC(=O)Cc2ccc(F)cc2F)c1 +CCCNS(=O)(=O)c1cnn(-c2ccccc2)c1 +Cc1ccc(C)c2c(C)c(C(=O)NCCCN3CCCC3=O)oc12 +CC(=O)c1cccc(NC(=O)NCc2cccs2)c1 +Cc1ccc(C(O)C2NCCc3ccc(F)c(C)c32)cc1 +CC(=O)Nc1ccc(C(N)=O)cc1C(=O)c1ccccc1 +CC(C)Cn1c(CN2CCC(=O)NCC2C)nc2ccccc21 +CC(C)C(=O)Nc1ccc(CNC(=O)c2cc(F)cc(F)c2)cc1 +CC(C)c1nc(CCNC(=O)c2ccccc2-n2cnnn2)cs1 +O=C(Nc1ccc2c(c1)OC(F)(F)O2)c1cccc2cccnc12 +O=C(CN1CCOCC1)Nc1ccc(NC(=O)c2ccsc2)cc1 +O=C(c1ccc(Cl)c(S(=O)(=O)N2CCCC2)c1)C1CC1 +Cc1cccc(C(C)C)c1NC(=O)c1cnn(-c2ccncc2)c1C +C#CCN1CCC(C(=O)Nc2ccccc2F)CC1 +CCC(CC)c1nnc(NC(=O)c2ccc(=O)n(C)n2)s1 +COC(=O)c1c(CC(=O)NCC2CC2)[nH]c(C(C)=O)c1C +O=c1c2oc3ccccc3c2nc2n1Cc1ccccc1-2 +Cc1cnc(NC(=O)CCn2ccccc2=O)s1 +COCCCC(=O)Nc1c(N)n(CC(C)C)c(=O)n(C)c1=O +CC(C)n1nc(O)c2c(-c3ccc(O)cc3)c3sc(=O)[nH]c3nc21 +CC(C)(C)c1ccc(C(=O)NCC(=O)OCC(=O)N2CCCC2)cc1 +CN(CCOCC1CC1)C(=O)Nc1cc2c(cc1Cl)OCCO2 +C#CCN1CCN(C(=O)NCC(C)c2ccc(F)c(F)c2)CC1 +Fc1ccc(CNc2cc(Cl)ccn2)c(F)c1 +O=C1C(=O)N(CC2CCCCC2)c2ccc(F)cc21 +c1ccc(-c2nc3sc4c(n3n2)CCNC4)nc1 +CCCC(C)(C)NC(=O)CCSc1ccccn1 +O=C(NC1CCCc2cn(C3CCCC3)nc21)c1cc[nH]n1 +CCOCc1ccccc1NC(=O)CNC(=O)C1CCCC1 +COc1ccccc1CN(CCO)C(=O)Nc1cccc(F)c1F +Cn1ccnc1C1(O)CCN(C(=O)c2ccccc2F)CC1 +Cc1cnc(C(=O)N2CCC(c3nc(-c4ccccc4)no3)CC2)cn1 +Cn1cc(-c2nc(C(=O)NCC(C)(C)c3cccs3)cs2)cn1 +Cc1ccc(CNS(=O)(=O)c2cc3c(cc2C)NC(=O)CO3)cc1 +C=CCN(C)S(=O)(=O)c1ccc(NC(=O)C2CC2C)cc1 +Cc1cc(C)n(-c2ccc(CNC(=O)N(C)C(C)C3CC3)cn2)n1 +CCN(C)C(=O)c1cccc(C(=O)Nc2cc(OC)ccc2F)c1 +CC(C)c1ccc(C(=O)NCCc2ccccc2)c(N)n1 +Cn1cnc(CNS(=O)(=O)c2c[nH]c3ncccc23)n1 +COc1c(Cl)cc(Cl)cc1C1NCCOC1C +COc1ccccc1OS(=O)(=O)c1ccc(F)c(Cl)c1 +N#Cc1ccc(-c2noc(-c3cccc(N4CCOC4=O)c3)n2)nc1 +CCOc1ccc2nc(-c3nccn3CCOC)ccc2c1 +CCNC(=O)CNC(=O)C1CCCN1C(=O)CC(C)(C)C +CN(C(=O)CN1Cc2ccccc2C(c2ccccc2)C1)C1CC1 +c1ccc(N2CCN(c3ncnc4c3oc3ccccc34)CC2)nc1 +CC(C)Oc1ccc(C(=O)N2CCCCCC2c2ccncc2)cn1 +CCOC(=O)N(C)CC(=O)NC1CCSc2ccc(Cl)cc21 +Fc1cc(Br)ccc1NCc1ccc[nH]1 +Cn1cccc(NC(=O)C2CCN(C(=O)N3CCCC3)CC2)c1=O +O=C(Nc1ccncc1)c1cccn(Cc2ccccc2F)c1=O +CCN(Cc1cnn(C)c1)Cc1cc(F)c(F)cc1F +O=C(Nc1nc(-c2cc(F)ccc2F)cs1)c1cccnc1 +Cc1nc(C(=O)N=c2sc3ccccc3n2C)cs1 +c1ccc2c(c1)ccn2CCc1nc(-c2cnccn2)no1 +Cc1cccc(C(=O)NC(C)C(=O)Nc2cccc(F)c2)c1 +O=C(NCCc1cccc(F)c1)c1ccnc(-n2ccnc2)c1 +O=S(=O)(Cc1ccccc1F)Nc1ccc(-c2ccccn2)cn1 +Cc1cc(CNc2cccc3[nH]ncc23)c(C)s1 +CN1CC(C(=O)NCc2ccnc(OCC3CC3)c2)CC1=O +O=S(=O)(Nc1ccc2cn[nH]c2c1)c1ccc2c(c1)OCCO2 +COCCOCCNC(=O)c1cccc2cn[nH]c12 +CCn1cc(C(=O)Nc2cccc(COc3cccc(F)c3)c2)cn1 +COc1ccc(NC(=O)c2ccc(-n3cccn3)cc2)cc1O +Cc1nc2ccccc2n1CCNC(=O)c1n[nH]c2ccccc12 +CCOc1c(OC)cccc1-c1nc(C)c(C(C)=O)s1 +CCn1cc(CCNC(=O)Nc2cccc(OC)c2)c2cccnc21 +CN(Cc1ccsc1)C(=O)Cn1cnc(N)n1 +COc1ccccc1Nc1nc(N)nc(CN2CCOCC2)n1 +COC(=O)CCCC(=O)c1cc(C)ccc1S(C)(=O)=O +Cc1cc(Oc2ccc(NC(=O)c3cnn(C)c3C)cc2)n[nH]1 +Nc1nccnc1C(=O)NCC(c1cccs1)N1CCCC1 +Cc1sc(NC(=O)C2CC2)nc1-c1ccc2c(c1)N(C)C(=O)CO2 +CCCCNC(=O)NCCCn1cnc2ccccc21 +N#Cc1cccc(Cn2c(=O)ccc3cc(F)ccc32)c1 +Cc1cc(C(=O)OCC(=O)N2CCc3ccccc3C2)on1 +CCCNC(=O)c1cnn2c3c(cnc12)C(=O)CC(C)(C)C3 +CC(C)Oc1ccc(C#N)cc1NC(=O)NCCC(=O)N(C)C +CC(C)N(C(=O)c1ccc(N2CCCC2)c(F)c1)C1CCC1 +O=C(Nc1cccnc1)C1CNCc2ccccc21 +COc1csc(C(=O)N2CCC(OCc3ccccc3C)CC2)c1 +COc1c(CN2CCN(C(=O)c3ccccc3O)CC2)c(C)nn1C +Cc1nc(CN2CCN(CC(=O)Nc3ccccc3F)CC2)n[nH]1 +COc1cccc2sc(OC3CN(S(C)(=O)=O)C3)nc12 +COc1ncccc1NC(=O)NCC(=O)NC(C)C +N#Cc1cccc(S(=O)(=O)N2CCCCC2C(N)=O)c1 +O=C(NC(Cc1ncc[nH]1)c1ccccc1)c1ccc(=O)[nH]c1 +Cc1cc(C(=O)Nc2cccc(-n3cnnc3)c2)c2c(C)nn(C)c2n1 +Cc1ccc(N)c(C)c1NC(=O)Cc1ccc(Cl)cc1 +Cn1cc(C(=O)Nc2ccc(N3CCOCC3)cn2)c(C(C)(C)C)n1 +CC(C)c1nnc2n1CC(NC(=O)c1cccnc1N(C)C)CC2 +COc1ccc(CN(C)C(=O)C2CC=CC2)cc1OC(F)F +CC(NC(=O)CCNC(=O)Nc1ccccc1)c1cccc(Cl)c1 +Cc1cccc(OCc2nc(C)c(C(=O)NC(C)C)s2)c1 +CS(=O)(=O)c1ccc(N2CCC(CO)CC2)c(S(C)(=O)=O)c1 +Cc1cc(CNC(=O)COc2ncccn2)nc(N2CCOCC2)n1 +COC(=O)c1ccc(Oc2nc(C)cc(OC)n2)cc1 +CN(c1ccc2sc(C(=O)NC(C)(C)C)cc2c1)S(C)(=O)=O +CCn1cnnc1-c1cccc(NC(=O)CCn2ccccc2=O)c1 +O=C(Nc1nc(CC(=O)N2CCCCC2)cs1)c1ccco1 +NC(=O)Cc1csc(NC(=O)C2Cc3ccccc3C(=O)O2)n1 +CC(=O)Nc1ccc(NC(=O)C2CCn3c(nc4ccccc43)C2)cc1 +O=C(Cc1ccc(Cl)cc1)Nc1ccc2c(c1)CCC(=O)N2 +O=C(NCC(=O)N1CCN(Cc2ccccc2)CC1)C1CC=CC1 +Cc1ccc(NC(=O)C(C)NC(=O)c2ccc(Cl)cc2)cc1 +COc1ccc(CC(=O)N2CCC(Oc3ccc(C)nn3)CC2)cc1 +Fc1cccc(C2CN(Cc3ccco3)CCO2)c1 +CC(NC(=O)c1csc(Cc2ccccc2F)n1)c1nc[nH]n1 +COC(=O)c1nsc(C(=O)NC2CCCCCC2)c1N +CC(C)(C)Oc1cc(CNC(=O)N2CCOCC2C2CC2)ccn1 +Cc1cccc2c1cnn2CCC(=O)NCc1csc(C2CC2)n1 +COc1ccc(NC(C)=O)cc1NC(=O)COc1cccc(Cl)c1 +CC(C)C(NC(=O)c1ccco1)C(=O)NCCc1ccc(F)cc1 +CCC(C)n1c(=O)[nH]c(=O)c2c1nc(NC)n2C +O=C(Cc1ccc(O)cc1)NCc1ccc2c(c1)CC(=O)N2 +CN(C)C(=O)CCCn1ccc(NC2CCCCc3ccccc32)n1 +O=C(COc1ccc(-c2ccccc2)cc1)N1CCNCC1 +Cc1nn2c(-c3ccccc3)ccnc2c1Br +CC(C)(CNC(=O)Nc1cccc(Oc2ccccc2)c1)C(N)=O +CCCCOc1cccc(C(=O)NCC2CCCO2)c1 +O=c1c(-c2ccccc2F)coc2c(CO)c(O)ccc12 +CC(=O)c1ccccc1NC(=O)CSc1ccc(F)c(F)c1 +Cc1cc(C(=O)Nc2nc3c(s2)CC(C)CC3)c2c(C)noc2n1 +CCS(=O)(=O)NCCN1CCc2ccccc2C1CO +Cc1ccccc1C(=O)Nc1ccc2c(c1)CN(C(=O)C1CC1)CC2 +CCNC(=O)c1ccc(Cl)cc1NC(=O)Cc1ccc(F)cc1 +COc1ccc(C)cc1NC(=O)Cn1nnnc1C(C)C +O=C(NCc1cc(F)cc(C(F)(F)F)c1)c1cc2c(cn1)OCC2 +O=C(COc1ccc(Cl)cc1Cl)Nc1cccnc1 +CN1CCN(C(=O)CCC(=O)Nc2nccs2)CC1 +CCNC(=O)c1ccc(NC(=O)CSc2ccccc2)c(C)c1 +Cc1cc(OCCCC(=O)Nc2cccn(C)c2=O)ccc1Cl +O=C(CCn1cncn1)N1CCCC1c1nc2ccccc2[nH]1 +CNC(=O)c1cc(NS(=O)(=O)c2ccccc2OC)ccc1F +CC(C)n1nnnc1-c1cccc(C(=O)NCC(=O)N(C)C)c1 +CC(=O)Nc1cccc(NC(=O)CSc2ccc(C)cc2)c1 +Cc1csc(C2(NC(=O)c3cccc(CC#N)c3)CCCC2)n1 +CC(C)n1c(CC(F)(F)F)nc2cc(N)ccc21 +CCc1nccn1-c1cccc(C2CCCN(Cc3ccccc3)C2)n1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)N(C)Cc1cccnc1 +O=C(CSc1nc(-c2ccccc2)cc(=O)[nH]1)Nn1cnnc1 +COc1ccc(OCCC(=O)NC2CCCCC2O)cc1 +CNC(=O)c1ccc(NC(=O)NCCC2CC3CCC2C3)cc1 +COc1ccccc1CNC(=O)c1cccc(C)c1 +COCCOc1ccc(CNC(=O)C2CCCN2C(C)=O)cn1 +Cc1ccc(C(=O)NC2(c3nc(C)no3)CCCCC2)cc1 +COc1ccccc1N(CC(=O)Nc1cccc(C)c1)S(C)(=O)=O +Clc1ccc(-n2cnnc2C2CCOCC2)cc1 +CCN(Cc1cnn(C)c1)C(=O)C#Cc1ccc2c(c1)OCO2 +O=C(Nc1nnc(CSc2ccccc2)s1)c1ccco1 +CCCC1CN(C(=O)CCc2ccccc2O)CCO1 +COc1ccc(CNC(=O)c2c(C)nn3c(C)cc(C)nc23)cc1F +Cc1n[nH]c(C)c1CNC(=O)N1CCC(C)CC(C)C1 +Cc1nc(C(C)(C)C)sc1C(=O)N1CCC(C(N)=O)C1 +CC(=O)N1CCC(C(=O)NC(c2ccccc2)c2ccco2)CC1 +CCOC(=O)N1CCN(c2ccc(C(=O)OC)cc2)CC1 +O=S(=O)(CC1CCOC1)c1ccc2ccccc2c1 +Cc1cc(C(=O)N2CCN(C(=O)c3cc(C)oc3C)CC2)[nH]n1 +O=C(Nc1ccccc1O)C1CCCc2ccccc21 +COc1ccc(O)c(C(=O)OC(C)C(=O)Nc2ccccc2F)c1 +CC(C)(C)c1ncc2c(n1)CN(C(=O)c1cc(F)cc(Cl)c1)C2 +CNC(=O)NCC(=O)N1CC(C)Oc2ccc(C)cc21 +COC(=O)C1(NC(=O)c2ncn(-c3ccccc3)n2)CCC1 +O=C(c1ccco1)N1CCN(C2=NS(=O)(=O)c3ccccc32)CC1 +O=C1CN(C(=O)CCSc2ccccc2F)CCN1 +COc1cccc(-n2ccnc2SC(C)C(=O)NC2CCCC2)c1 +CCC(=O)Nc1ccc(NC(=O)NCC(C)(C)N2CCOCC2)cc1 +Nc1cc(N)nc(SC(C(=O)N2CCCC2)c2ccccc2)n1 +CC(C)c1cc(Br)ccc1NCC(=O)N1CCCC1 +CC(NC(=O)NC1CCN(c2ncccn2)CC1)c1ccccn1 +CCCCS(=O)(=O)N(C)C(C#N)c1ccc(CC)cc1 +CCCCC(=O)Nc1nnc(S(C)(=O)=O)s1 +COCc1noc(C(C)Sc2nnc(C)n2-c2ccccc2C)n1 +Cc1n[nH]c2ncc(C(=O)NCC3CCCC(C)C3)cc12 +CC1CCc2c(sc3ncnc(NC(C)C(N)=O)c23)C1 +N#Cc1ccccc1Oc1cc2c(cc1N)OCCO2 +c1coc(-c2nnc(CN3CCOC(CC4CCCCC4)C3)o2)c1 +Cc1nn(-c2ccccc2)c(CSc2nccn2C)c1C#N +CC(C)c1cc(NC(=O)c2ccc3c(=O)n(C)c(=O)n(C)c3n2)on1 +Cc1ccnc(NC(=O)NCCCc2nc3ccccc3[nH]2)c1 +COC(=O)C1c2ccsc2CCN1C(=O)c1ccccc1OC +Cc1cccnc1NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1 +O=S(=O)(CC1CCCO1)c1ccc(Cl)cc1 +Cc1cc(NC(=O)CSc2nnc(-c3ccncc3)o2)no1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCc1nc(-c2ccsc2)no1 +CCn1nc(C)cc1C(=O)N(CC1CCCO1)c1ccncc1 +CNC(=O)c1cc(C)ccc1NC(=O)c1ccnc(OC2CCC2)c1 +O=C(C(Cc1ccccc1)n1cnnn1)N1CCCc2ccccc21 +O=C(C1COCCO1)N1CCCC(N2CCNC2=O)C1 +O=C(CC(c1cccc(O)c1)c1ccccc1Cl)N1CCOCC1 +Cc1cccc(CC(=O)Nc2cccc(N3CCCS3(=O)=O)c2)c1 +COc1cccc(CNC(=O)COc2cccc(OC)c2)c1 +O=C1CCN(C(=O)COc2ccccc2F)CC1 +NC(=O)Cn1cc(NC(=O)NC2CCOc3ccccc32)cn1 +Cc1cccc(OCCn2nc(C)c(C#N)c2N)c1 +Cc1ccc(N2CCN(C(=O)C3CCCCC3)CC2)cc1N +CCOC(=O)c1c(SCC)[nH]c2cc(F)c(F)cc2c1=O +COc1ccc(S(=O)(=O)N(C)Cc2ccccc2F)cc1 +COc1ccc(CNC(=O)c2c(C)oc3ncn(C)c(=O)c23)cc1 +Cc1ccccc1Cn1c(CNC(=O)C2CC2)nc2ccccc21 +CC1(C)C2CCC1(C)C(NC(=O)c1n[nH]c(=O)[nH]1)C2 +CN(CCc1ccccc1)C(=O)NCc1cn(-c2ccccc2)nn1 +Cc1cccc(Cn2cnc(NS(=O)(=O)c3cn(C)nc3C)n2)c1 +CC(NC(=O)C1CC(=O)N(C)C1)C1CCCCC1 +COC(=O)C1(N(C)C(=O)c2ccnn2C)CCCCC1 +COCCCNC(=O)C1(c2cccc(Cl)c2)CCC1 +CCOC(CC)C(=O)Nc1ccc(C(N)=O)c(Cl)c1 +CCOC(=O)C=C(C)Nc1ccc(OC)cc1N +Cc1ccccc1C1CN(C(=O)OC(C)(C)C)CCN1 +CCOC(=O)C(C)(NC1CCCC1)c1ccccn1 +CCN(Cc1nc(-c2ccncc2)no1)c1ccccc1 +Cc1ccsc1CNc1ccc2nnc(C(F)(F)F)n2n1 +COc1ccc(CNC(=O)c2cn(C)c3ncccc23)cc1OC +COc1cc(C2NCCc3ccc4c(c32)CCO4)ccn1 +CC(NC(=O)Nc1nncs1)c1nncn1C +CCN1CC(C(=O)N2CCCCC2Cn2nc(C)cc2C)CC1=O +COc1ccc(C(=O)NCCC(O)C(C)(C)C)cc1OC +Oc1ccc(-c2nccc(-c3cccs3)n2)cc1 +COc1ccc(F)cc1C(=O)Nc1cccn(C)c1=O +COc1ccc(C(=O)OCC(=O)Nc2cccc(C)c2)cc1 +CCNC(=O)CN1CCN(C(=O)CCn2cc(C)cn2)CC1 +CNC(=O)c1cccc(NC(=O)c2ccc(OC(F)F)cc2)c1 +Cc1csc2nc(O)c(C(=O)NCc3ccncc3)c(=O)n12 +CC(NC(=O)c1ccc(=O)[nH]c1)c1cccc2ccccc12 +CCC(C)NC(=O)CNc1cccc(C(F)(F)F)c1 +COc1ccc(F)c(NC(=O)NCC2CCCC2O)c1 +COc1ccc(C)cc1C1(CNC(=O)c2cc(C)n[nH]2)CCOCC1 +COc1ccc(NC(=O)c2ccc(COc3ccc(C#N)cc3)o2)cn1 +CS(=O)(=O)c1ccc(-c2cc(Cl)c(C#N)cn2)cc1 +COc1cccc(CCC(=O)NC2(C#N)CCC3(CC2)OCCO3)c1 +COc1cc(C#N)ccc1Oc1ncnc2ccccc12 +COCC(NC(=O)c1ccc(OC)cc1Br)C(N)=O +COCc1nnc(NC(=O)CNc2ccccc2)s1 +COC(=O)c1csc(NC(=O)C(C)N2CCc3ccccc3C2)c1 +COc1ccc2c(CC(=O)NC(C)(C#N)CC(C)C)coc2c1 +Cc1cccnc1NC(=O)Cc1c[nH]c2ccc(F)cc12 +O=C(NCc1ccoc1)NCC(O)c1cccc(F)c1 +c1ccc(OC2COC3(CCN(Cc4nccs4)C3)C2)nc1 +CCc1cc(OCC(=O)Nc2cc(C)on2)nc(N2CCCC2)n1 +Nc1ccccc1CC(=O)OCCc1ccccc1 +Cc1ccccc1NC(=O)COc1cc(F)ccc1N +O=C(CO)N1CCN(C(=O)CCCOCc2ccccc2)CC1 +CN1CCN(C(=O)CNC(=O)c2cccs2)CC1 +CCOC(=O)C1CC(C(=O)OCC)C(C)(O)CC1=O +O=c1c2cc(NCCOc3ccccc3F)ccc2nc2n1CCC2 +CC(NC(=O)c1cccc(F)c1)c1ccc(-n2cccc2)cc1 +Cc1cc(C)n(-c2ccc(CNCc3cnn(C(C)(C)C)c3)cn2)n1 +O=C(Nc1ccccc1C(=O)NC1CC1)c1ccncc1F +CCOC(=O)Nc1ccc2c(c1)C(=O)N(C)CCO2 +OCCn1nc(-c2cccs2)cc1NCc1cc(F)ccc1F +Cc1cccc2c1N(C(=O)CCc1nnc(-c3ccccc3)o1)CCC2 +CC(=O)c1ccccc1NC(=O)CCCSc1ccccn1 +COC(=O)NCC(=O)NC(C)c1c(Cl)ccc(F)c1Cl +Cc1ccc(F)cc1NC(=O)CSc1nnc(-c2ccoc2C)o1 +CN(C(=O)CNc1cc(Cl)ccc1Cl)C1CC1 +CC(=O)c1ccc(NC(=O)c2csc(C)n2)cc1 +Cc1ccc(N)c(C)c1S(=O)(=O)Nc1cnccn1 +Cc1nc(NCCCNS(C)(=O)=O)c2c(C)c(C)sc2n1 +CCOc1ccc(C(=O)Nc2ccc(F)c(NC(=O)OC)c2)cc1 +N#CC1(NC(=O)CCc2nc(-c3ccco3)no2)CCCCC1 +COc1ccc(-n2ncc(C(C)(C)O)c2C)cc1OC +CC(=O)c1cccc(NC(=O)N(C)Cc2nc3ccccc3n2C)c1 +CN(C)C(=O)c1ccc(C#CCNC(=O)c2ccccc2Cl)cc1 +CCc1c(C(=O)NC(C)CO)cnn1-c1ccccc1 +COc1cc(OC)c(NC(=O)c2cc(-c3ccccc3)no2)cc1F +CNC(=O)c1ccc(Cl)cc1NCC(=O)Nc1ccc(C)c(F)c1 +N#Cc1cc(Cl)ccc1N1CCCC(CCC(N)=O)C1 +CC(C)CC(C#N)CCC(=O)N1CCC(C)CC1 +COC(=O)c1ccc(NC(=O)NCC(C)N2CC(C)OC(C)C2)cc1 +Cc1cnn(CC2CCCN2C(=O)C2Cc3ccccc3S2)c1 +CNC(=O)c1ccc(S(=O)(=O)NCCC2CCCO2)cc1 +CNC(=O)c1cccc(OC(=O)c2csc(-c3ccco3)n2)c1 +C=CCNC(=O)CC1CCN(C(=O)c2cccnc2)CC1CC +Cc1ccccc1CNC(=O)CSc1nncc2ccccc12 +Cc1ccc(NC(=O)N2CCC(c3ccncc3)CC2)cc1F +CCOCC(C)NC(=O)c1cnc(N)c(Cl)c1 +C#CCN(Cc1ccc(F)cc1)C(=O)NCCCOC +CC(=O)NCCNC(=O)N1CCC(OCc2ccccc2F)CC1 +CCOC(=O)Cn1cc(-c2nc(C)no2)ccc1=O +Cc1ccc2nc(C(C)N3CCN(CCO)CC3)[nH]c2c1 +COCc1cccc(CNc2ncccc2Cl)c1 +O=C(NCc1cccnc1)N1CC2CC(F)C(O)C2C1 +CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)C(C)(C)C)cc1 +Cc1cc2c(N)cccc2c(C(=O)Nc2cccc(F)c2)n1 +Nc1c(-c2ccccc2F)noc1C(=O)NC1CCCC1 +Cc1nc(N(C)C)ncc1C(=O)N1CCC(c2ccccc2Cl)C1 +N#Cc1c(Cl)cccc1N1CCN(CC(=O)NC2CC2)CC1 +CN1CC(c2nc(-c3cccc(CN4CCOCC4)c3)no2)CC1=O +COc1ccc(-n2ccc(=O)c(OC)n2)cc1OC +CCC(C)OC(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +CCCCNC(=O)c1cnn2c1CN(C(=O)c1ccc(F)cc1)CC2 +CN(Cc1ccccc1F)C(=O)CNC(=O)Cc1ccccc1 +COc1ccc(NC(=O)c2cc3ccccc3o2)c(N)c1 +CCOc1ccc2c(C(=O)NCc3cnn(C)c3C)cc(=O)oc2c1 +C=CCCc1nnc(C(N)c2cc(F)ccc2F)o1 +O=C(Cn1cnc2ccccc21)Nc1ccccc1OC(F)F +COc1cc(F)c(S(=O)(=O)NC(C)c2cccnc2)cc1OC +CC(C)OCC(=O)NC1CCSc2ccc(Cl)cc21 +COc1ccc(CNC(=O)Nc2cccc(C)c2)c(OC)c1 +CCOC(=O)c1csc(NC(=O)COc2ccccc2Cl)n1 +Fc1cccc(OC2CC3CN(Cc4ccccn4)CCN3C2)c1 +Cc1c(-c2csc(CC#N)n2)c2ccccc2n1C +CC1(C)Oc2ccc(NC(=O)NC3CCCCC3)cc2NC1=O +O=C(Nc1cc(Br)ccc1F)c1cn2cccnc2n1 +Cc1ccc(NC(=O)Cn2cnnn2)c(OCc2ccccc2)c1 +COCc1ccccc1CNC(=O)N1CCC(OCC(C)C)CC1 +Cc1cc(C)n(Cc2ccc(C(=O)N3CCC(C)CC3)o2)n1 +CC(C)(C)C(=O)N1CCN(C(=O)NC2CCCC2)CC1 +CCC(NC(=O)N1CCCC(CNC(C)=O)C1)c1cccs1 +Cc1nc(C)c(C(=O)NC(C)(C)CNC(=O)OC(C)(C)C)s1 +CCS(=O)(=O)NCCN1CCCc2cc(Br)ccc21 +COc1cc(Cn2cnc3ncccc3c2=O)ccn1 +CN(Cc1cc(C#CCO)cs1)S(=O)(=O)C(F)F +COC(=O)CCCNC(=O)Nc1cccc(Cl)c1 +O=C(NCc1nc[nH]n1)c1csc2ccccc12 +CC=Cc1ccc(OS(=O)(=O)c2c(C)noc2C)c(OC)c1 +Cc1ncsc1C(=O)OCc1nnc(-c2ccccc2Cl)o1 +O=C(NC1(c2cccc(Cl)c2)CC1)c1ccco1 +CC1Cc2ccccc2N1C(=O)CCC(=O)c1ccc(F)cc1 +CCc1ccc(C(NC(=O)Cc2c(C)nc(C)[nH]c2=O)C(C)C)cc1 +COc1ccc(-c2ccc(C(=O)NCCCO)o2)cc1 +CCc1ccc(C(C)NC(=O)c2ccc(CNC(N)=O)cc2)cc1 +COC(=O)c1c(NC(=O)c2ccc(C#N)cc2)sc2ccccc12 +COC(=O)c1ccc(NC(=O)c2ccc(O)cc2O)cc1 +Cc1ccc2ncc(C(=O)Nc3cccc(N4CCOCC4)c3)n2c1 +COCCn1c(=O)n(CC(=O)NC2CCCCC2)c2cccnc21 +CN(Cc1ccccn1)C(=O)NC1CCc2cc(Cl)ccc21 +COc1ccc(C(=O)NCCC(O)c2cc(C)oc2C)cc1OC +O=C(Cc1csc2nc(-c3ccccc3)cn12)NCC1CC1 +COCc1cccc(NC(=O)c2cc(Br)c[nH]2)c1 +Cc1cccc(CN(C)S(=O)(=O)c2ccc(N)cc2)c1 +COCC(C)N1CCN(C(=O)c2ccccc2OC(C)C)CC1 +O=C(C1CCCO1)N1CCCn2nc(-c3cccc(Cl)c3)cc2C1 +O=C(C#Cc1ccccc1)N1CCN(C(=O)c2cccc(O)c2)CC1 +Cc1ccc(C(CNc2nccnc2OC(C)C)N2CCOCC2)o1 +O=C(c1cc(F)ccc1F)N1CCOCC1C1CC1 +COC(=O)C1CC1C(=O)Oc1cccc(-n2cccn2)c1 +COc1ccc(-c2noc(C(N)=O)c2N)cc1OC +CNC(=O)c1ccccc1NC(=O)c1ccccc1Br +Cc1csc(NC(=O)NCC2(c3ccccc3)CCC2)n1 +COc1cc(C)ccc1NC(=O)c1cccc(OC)c1O +COc1ccc(COC2C(C)C(=O)OC3COC(C)(C)OC32)cc1 +O=C(Nc1cnc2ccc(N3CCCC3)nn2c1=O)c1ccccc1 +OCCn1c(-c2ccccc2O)nc2ccccc21 +CC(C)CCN1C(=O)CCC2CN(C(=O)Cc3ncccn3)CCC21 +C=CCNC(=O)Nc1ccc(C(=O)N2CCCCCC2)cc1 +Cc1cc(C)cc(OCC(=O)Nc2c[nH]nc2C)c1 +O=C(OCc1nnc(C2CC2)n1C1CC1)c1ccoc1 +CCOC(=O)c1c[nH]c2c(Br)cc(C)cc2c1=O +CCn1c(C)cc(C(=O)Nc2cc(C)nn2Cc2ccccc2)c1C +Cc1cc(C)c(-c2nc(-c3cccs3)no2)c(=O)[nH]1 +CCC(C)NC(=O)c1cnc(-c2ccco2)nc1N +COC(=O)C1(N(C)C(=O)c2ccc3c(c2)nc(C)n3C)CCCCC1 +CC(C)(C)OC(=O)NCC(=O)NCC1CCCOC1 +COc1ccc(CNC(=O)CNC(C)c2cccnc2)cc1 +CCC(O)c1cc(Br)c(OC)cc1OC +CN(Cc1ccc2c(c1)OCO2)c1ncccc1N +Cc1ccc(C(=O)NCC(=O)NC2CC2)cc1F +CC(CNc1cncc(C(N)=O)n1)c1nc2ccccc2s1 +CC(C)(C)OC(=O)NCC1NCCc2ccc(F)c(F)c21 +Cn1cc(C(=O)Nc2ccc3nccnc3c2)c(C(C)(C)C)n1 +O=C(NCCN1CCOCC1)Nc1ccc(OCC(F)(F)F)cc1 +Cc1csc(Sc2ccc(NC(=O)Nc3cn[nH]c3)cc2)n1 +CCN(CC(C)C#N)C(=O)NCc1ccccc1F +Cc1cccc(S(=O)(=O)Nc2ccc(C)c(N)c2)c1 +CCn1c(=O)oc2ccc(C(=O)Nc3cccc(SC)c3)cc21 +CN(Cc1ccccc1)C(=O)CSc1ncnc2ccsc12 +CCCc1nc(C)c(C(=O)Nc2cc(C)on2)s1 +CC(C)(C)C(=O)NCCn1ncc2c(NCc3ccco3)ncnc21 +Cc1ccc(SC(C)C(=O)N(C(C)C)C(C)C)nc1 +CC(C)Sc1ccc(N2CCNC(=O)C2)nn1 +CCNC(=O)C(C)NC(=O)CCOc1ccc(F)cc1 +O=C1CC(C(=O)N2CCCC2c2ccccn2)CN1C1CCCC1 +CN(C)C(CNS(=O)(=O)c1ccc(Cl)cc1)c1cccs1 +Cn1cccc1C(=O)N1CCN(c2cccc(Cl)c2)C(=O)C1 +O=C(c1cccs1)N1CCOC2CCC1C2Oc1ncccc1F +COc1cccc(C(=O)c2c(N)oc3c2C(=O)CCC3)c1 +O=C1CCC2(CCCO2)CCN1Cc1ccc(C(F)(F)F)c(F)c1 +COc1cc(CNC(=O)N(Cc2ccc(Cl)cc2)C2CC2)ccn1 +CCc1cnc(NC(=O)c2c[nH]c3cccc(F)c23)s1 +CN(CCO)C(=O)NC12CC3CC(CC(C3)C1)C2 +CC(C)(C)n1ncc2c(NC3CCCN(C(N)=O)C3)ncnc21 +CN(C)C(=O)c1cn(-c2ccc(Cl)cc2)c(=O)c2ccccc12 +COc1ccc(Cl)cc1NC(=O)NCCOCC(F)(F)F +CSc1nnc(Cc2c(F)cccc2Cl)o1 +COc1nn(C)cc1C(=O)NCc1ccc2c(c1)OCO2 +COC(=O)c1ccoc1COC(=O)c1ccc2nc(C)c(C)nc2c1 +O=C(NCC1CCCO1)Nc1cc(N2CCCC2=O)ccc1Cl +Cc1ccccc1-n1cnnc1SC(C)c1nc(C2CC2)no1 +COc1ccc(NC(=O)CCCC(=O)c2ccccc2)cn1 +Fc1cc(F)c2c(c1)CCNC2c1cnccc1Cl +CC(NC(N)=O)C(=O)NCCOc1ccc(Br)cc1 +COc1ccc(CN(C(=O)CN2C(C)COCC2C)C2CC2)cc1 +COC(C)(C)CNC(=O)NCc1cn(C)nc1-c1ccccc1 +CCc1onc(C)c1NC(=O)Nc1ccc(F)cc1OC +COc1ccc(C)cc1NC(=O)c1nc2ccccc2s1 +CCN(C)S(=O)(=O)c1c(C)nn(CC(O)c2ccccc2)c1C +Cn1cnc(CNC(=O)N2CC(O)CC2c2cc(F)ccc2F)n1 +COc1cccc(NCc2ccc(F)cc2F)n1 +CCCc1noc(Cn2c(=O)oc3ccccc32)n1 +CCOc1cc(NCc2ccc(F)cc2)nc(COC)n1 +CC(=O)Nc1ccc(CNc2cccnc2OC(C)C)cc1 +COc1ccc(C)cc1CN(C)C(=O)c1ccc2c(c1)OCC(=O)N2 +O=C(c1ncoc1C1CC1)N1CCCCC1CCc1ccc(O)cc1 +COc1ncccc1CNC(=O)c1c(F)cccc1Cl +CC(c1cc(F)ccc1F)N(C)C(=O)CNC(=O)c1cccs1 +COC(=O)CN(C(=O)CCn1cccn1)C(C)C +CCCS(=O)(=O)NCc1ccc(S(C)=O)cc1 +O=C(NCC1(O)CCc2ccccc21)C1CC=CCC1 +C=CCNC(=O)C1Cc2ccccc2CN1C(=O)c1ccco1 +COc1ccccc1C1CCN(Cc2cc(C#N)cs2)C1 +CCS(=O)(=O)N1CCN(C)C2(CCC(=O)N(CC3CC3)CC2)C1 +CCOc1ccccc1C(=O)NCCCn1ccc2cccnc21 +CCOc1ccccc1NCCCc1ccncc1 +O=c1c2c(-c3ccccc3)n3ncnc3nc2ccn1CCO +COc1cccc(C2(C(=O)NCC(=O)Nc3cn[nH]c3)CCCC2)c1 +N#Cc1cccc(NC(=O)NCCNC(=O)c2ccccc2Cl)c1 +CSc1nc(C(=O)N=c2[nH]nc3ccccn23)c2ccccn12 +Cc1nc(-n2cccc2)sc1C(=O)NCc1cccnc1 +COC(=O)CCNC(=O)c1cccc(C(F)(F)F)c1 +CC(C)CC1NCCc2c1cc(F)cc2C(F)(F)F +CCOC(=O)CN(C)C(=O)c1cccc(OCC)c1 +CC(COc1ccccc1)OC(=O)Cn1ccc(=O)n(C)c1=O +COCCNC(=O)NCC#CCOc1cccc(C(F)(F)F)c1 +CCCC(=O)Nc1nc2ccc(NC(=O)CC)cc2s1 +CC(C)C(NC(N)=O)C(=O)NCc1ccccc1Cl +Cc1ccc(C(=O)N2CCN(C)c3cc(F)ccc32)o1 +CCCN(CCC)C(=O)CSc1ncnc2ccsc12 +Cc1noc(C)c1C(C)NC(=O)Cc1csc(-c2nc[nH]n2)n1 +CCn1c(C)nnc1SCC(=O)Nc1cc(OC)ccc1OC +COc1ccc(C(=O)N(CCC#N)Cc2ccco2)c(OC)c1 +CCCn1nnnc1CSc1nnc(SCC)s1 +CC(=O)N(C)Cc1ccccc1NCc1nccn1C(F)F +Cc1ccnc(C(NC(=O)c2cc3ccccn3c2)C2CC2)n1 +O=C1C2CCCN2C(=O)CN1Cc1cccc(Oc2ccccc2)c1 +Nc1ccc(SCc2cc(=O)n3ccsc3n2)cc1 +N#CCCN(C(=O)COC(=O)c1ccc(O)cc1)c1ccc(F)cc1 +CC(C)OC(=O)c1cccc(S(=O)(=O)N2CCCCC2C)c1 +O=C(c1ccoc1)N1CCN(c2ncccn2)CC1 +CC(C)CCNC(=O)c1cc2ccccc2oc1=O +O=C(CN1CCCCC1=O)Nc1cccc(Cn2cccn2)c1 +CCCCN(CC)C(=O)c1cc(OC)ccc1O +CCc1ncnc(N2CCN(C(C)CO)CC2)c1F +Cn1cc(C(=O)NC(c2cccs2)C2CCCC2)cn1 +O=C(c1sc2ccccc2c1Cl)N1CCCS1(=O)=O +CCC(CC)N(C)C(=O)c1[nH]c(C)c(C(C)=O)c1C +CC(C)CC(=O)Nc1ccc(Cc2ccncc2)cc1 +C=C(C)Cn1nc(CO)cc1-c1cc(Cl)ccc1OC +Cc1ccc(C(=O)N2CCc3cc(CNC(=O)C4CC4)ccc32)cc1 +CCN1CCOC(C(=O)N2CCN(C)c3cc(F)ccc32)C1 +Cc1nccn1-c1ccc(C(C)Nc2nc(C3CC3)no2)cc1 +CCOc1ccc(NC(=O)c2nnn(-c3ccc(F)cc3)c2N)cc1 +CC(C)C(C)NC(=O)c1ccc(-c2ccco2)[nH]c1=O +CN(CCC(F)(F)F)C(=O)c1ccc2c(c1)NC(=O)CS2 +COc1cc2c(cc1O)C(c1ccncc1)NCC2 +CCc1ccc(C(=O)C(C)OC(=O)c2ccc(C(N)=O)cc2)cc1 +Cc1nc(SCC(=O)NC2CCOCC2)c2ccccc2n1 +COc1nc(OCC#N)nc(N2CCOCC2)n1 +Brc1cccc(CCc2ncco2)c1 +COc1ccccc1NC(=O)N1CCCN(S(C)(=O)=O)CC1 +CCOC(=O)Cc1coc2cc(NCc3cccnc3)ccc12 +Cc1ccc(C=CCC(=O)Nc2sccc2S(C)(=O)=O)cc1 +CNS(=O)(=O)c1ccc(NC(=O)NCc2sccc2C)cc1 +NC(=O)CN1CCN(Cc2ccc(-c3ccccc3F)s2)CC1 +Cc1noc(CCCC(=O)Nc2nc(C(C)C)cs2)n1 +Cn1c(C(=O)N=c2[nH]cc[nH]2)cc2cc(F)ccc21 +CNC(=O)c1cc(NC(=O)C(C)OC)ccc1F +Cc1nc(-c2ccc(NC(=O)Cc3noc4ccccc34)cc2)cs1 +Cc1ccc(CCNC(=O)CN2C(=O)COc3ccccc32)cc1 +CC(NC(N)=O)C(=O)N(C1CCCCC1)C1CC1 +CC(C)n1ncc2cc(C(=O)N3CCCC(C(F)(F)F)C3)cnc21 +Cc1nn(C)c(C)c1C1CCCN1c1cnc2ccccc2n1 +O=C(NCc1ncc(-c2ccccc2)[nH]1)c1cc(-c2ccccc2)no1 +Cc1cc(NC(=O)COC(=O)c2ccc(N3CCCC3=O)cc2)no1 +CN(C)C(=O)CSc1nc2cc3c(cc2cc1C#N)OCCO3 +COc1nc(C(=O)NC(C)c2nnc3ccccn23)cc2ccccc12 +CSc1ccc(NC(=O)C2CCN(C(C)=O)CC2)cc1Cl +COC(=O)c1cccc(C#Cc2cccc(NC(=O)c3ccoc3)c2)c1 +CCOc1ccc(C(=O)CNCc2ccccn2)cc1N +O=C(Nc1ccccc1S(=O)(=O)N1CCOCC1)C1CC1 +CCCn1cc(C(=O)CSc2nnc[nH]2)c2ccccc21 +CNCC1NCCc2c(F)cc(Br)cc21 +Cc1noc(C(C)C)c1C(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +Cc1cc(NC(=O)C2CC(=O)N(Cc3ccccn3)C2)[nH]n1 +CCCCN(C)S(=O)(=O)c1cc(S(C)(=O)=O)ccc1C +CCC(=O)N(CC)Cc1cc2ccc(C)cc2[nH]c1=O +CCC(Sc1cc(C)ncn1)C(=O)Nc1cccc(O)c1 +CCCCN(CCCC)C(=O)C1CN(C(C)=O)C1 +Cc1nc(CSc2nccc(C(F)(F)F)n2)no1 +CC(C)CNC(=O)c1nc(-c2ccccc2)oc1C1CC1 +O=C(Nc1ccc(CCO)cc1)c1ccc(F)c(F)c1 +CCn1nnnc1-c1cccc(C(=O)NCc2cccc(C)c2)c1 +Cc1ncccc1C(=O)Nc1ccc(Oc2cccnc2)nc1 +Cc1cccc(NC(=O)Cn2ncc3c(N4CCCC4)ncnc32)c1 +CCOc1ccc(F)c(C(=O)Nc2cccc(S(C)=O)c2)c1F +COCc1ccccc1CNC(=O)c1cnc2ccc(C)cn12 +COc1ccc(C(NC(=O)C(C)OC)c2ccc(F)cc2)cc1 +Cn1nc(CNC(=O)c2cccc(Cl)c2)cc1C1CC1 +OCc1ccc(OCCc2ccc3c(c2)OCO3)cc1 +COC(=O)C1=C(C)N=C(C)C(C(=O)OC)C1C(N)=O +CC(C)C1Oc2ccccc2N(CC(=O)NCc2ccco2)C1=O +O=C(Cn1cnnn1)Nc1cccn(Cc2ccc(F)cc2)c1=O +COc1ccc(F)cc1NC(=O)c1cnn(CC(C)C)c1C +C=CCSc1ncccc1C(=O)NCc1ccccc1 +O=C(NCC1CC1)C1CCC2C(CCN2c2ncc(F)cn2)O1 +Fc1ccc(Cl)cc1NCc1nccn1C(F)F +COc1cccc(C(=O)NC2CN(C(=O)OC(C)(C)C)C2)c1F +COc1cccc(C(=O)Nc2ncc(C#N)s2)c1OC +CN(C)C(=O)C(Cc1ccccc1)NCC=Cc1ccccc1 +Cc1ccnc(NC(=O)c2ccc(O)c(Cl)c2)c1 +CCOc1ccc(NC(=O)C(C)NC(=O)c2ccoc2)cc1Cl +Cc1n[nH]c(C)c1N1CCN(C(=O)c2ccc(N(C)C)cc2)CC1 +Cn1cc(C(=O)NCc2ccc(C#N)cc2)c(C(C)(C)C)n1 +CC(C)NC(=O)c1ccc(Cl)c(NC(=O)c2ccoc2)c1 +CCn1nc(C)c(CNc2nncc(-c3cccc(OC)c3)n2)c1C +NC(=O)C(NC(=O)CCC(F)(F)F)c1ccc(F)cc1 +Cc1ccc(NCc2cccc(O)c2)cc1S(C)(=O)=O +O=C(C1CC(=O)N(c2cccc(F)c2)C1)N1Cc2cncnc2C1 +CCC1Oc2ccc(O)cc2N(CC(=O)NC)C1=O +Nc1cc(C(=O)Nc2cccc(Cl)c2)ccc1F +O=C(OCc1ccccc1)C1CCCN1C(=O)CCc1ccsc1 +C=CCNC(=O)C1(NC(=O)c2c[nH]c3ncccc23)CCCCC1 +Cc1nc(CN2CCN(Cc3cc4ccccc4s3)CC2)oc1C +CCc1nnsc1C(=O)NC(C)c1nc(-c2ccc(F)cc2)no1 +O=C(Nc1cccc(F)c1)c1cc2ccccn2n1 +CCC1CCCC(NC(=O)CN(C)C(=O)C(C)n2cccn2)C1 +O=C1Nc2ccccc2C(=O)N2CCN(C(=O)c3ccco3)CC12 +Cc1nn2c(=O)c(Cc3ccccc3)c(C)[nH]c2c1-c1cccnc1 +CC(=O)NCC(=O)N1CCc2ncc(Cn3cncn3)n2CC1 +CC(C)c1nc2cc3c(cc2n1C(C)(C)C)OCCO3 +CC(C)(C)NC(=O)C1CCN(S(C)(=O)=O)CC1 +CCC(NC(=O)C(C)NC(N)=O)c1ccc(OC)cc1 +Cc1cc(C)c(NC(=O)COCCOc2ccccc2)c(C)n1 +N#Cc1ccsc1NC(=O)c1cc(Cl)c2c(c1)OCCO2 +CCCc1noc(C2CCN(S(=O)(=O)c3ccccc3)CC2)n1 +CCN(C(=O)CNc1ccc(C(=O)N(C)C)cc1)c1ccccc1 +Cc1c(N)cnc(N2CCc3ccccc3C2)c1C#N +Cc1cc(C)n(Cc2coc(-c3cccs3)n2)c(=O)c1C(N)=O +COC(C)(CNC(=O)c1cn(C)nn1)c1ccccc1F +CCC(=O)N1CCc2sc(C(=O)NCc3ccco3)cc2C1 +CCC(C)NC(=O)c1cnc(-c2ccc(C)cc2)nc1N +Cc1ccccc1OCCNC(=O)NCc1cccs1 +COc1cc(C#CBr)cc(OC)c1OC +CCc1onc(C)c1NC(=O)NCCc1cc(F)cc2c1OCOC2 +CCOc1c(OC)ccc2c1CCNC2c1cnccn1 +CCC(CC)c1cc(C(=O)NCc2cccnc2-n2cccn2)on1 +Cc1nn(-c2ccc(F)cc2)c(C)c1CCC(=O)N1CCCCC1 +O=C(NCCc1nc(-c2ccccc2)no1)C1CCC1 +CN(C)C(=O)CCNC(=O)CCSc1nnnn1C +CCC(C)(CCO)NC(=O)NCC#Cc1ccccc1 +CC(=O)Nc1nc(C(=O)N(C)Cc2ccc(C3CC3C)o2)cs1 +COc1ccc2c(CC(=O)NCc3cscn3)cc(=O)oc2c1 +O=C(NCc1ccccc1F)c1cncc(Br)c1 +CC(=O)N1CCc2ccc(NS(=O)(=O)C(C)C)cc21 +CC(C)(NS(C)(=O)=O)c1nc(-c2cccs2)no1 +O=C1NC2CCCCC2N=C1CC(=O)c1ccc(Br)cc1 +N#Cc1ccc(NC(=O)C2CC=CCC2)cc1Cl +O=C(CCNC(=O)c1ccsc1)NCc1ccc(F)cc1 +CC(CO)NC(=O)c1cc(-c2ccco2)n(-c2cccc(Cl)c2)n1 +CCOC(=O)N1CCC(NC(=O)Cn2ccc(C(F)(F)F)n2)CC1 +CCCCOC(=O)C1C2C=CC3(CN(CC4CCCO4)C(=O)C13)O2 +O=C1COc2ccc(C(=O)Cc3ccc(C(F)(F)F)cc3)cc2N1 +COC(=O)c1nsc(C(=O)N2CCCCCC2)c1N +Cc1nc(CN(CCC#N)CCN2CCOCC2)cs1 +CSc1ccc(C(=O)Nc2nc(C)c(C(C)=O)s2)cc1 +OCC1CCCN(c2nc3ccccc3nc2NC2CC2)C1 +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2ncccc2O)c1C +CCNC(=O)CN(CC)C(=O)CSc1ccc(Cl)cc1 +CN1CC(C(=O)Nc2nc(Cc3ccc(F)cc3)n[nH]2)CC1=O +Cc1cc(C)n(-c2ccc(NC(=O)NCC3CCCO3)cc2F)n1 +CCNC(=O)NC1(C(=O)NC(C)c2cccc(OCC)c2)CCCC1 +CCOC(=O)C1(CO)NC(=O)CC1c1cccnc1 +c1cncc(CN2CCOCC2c2csc(N3CCCC3)n2)c1 +CN(Cc1ccc2c(c1)OCO2)CC(C#N)CCC#N +COC(=O)c1ccc(NCc2ccccc2C#N)cc1 +Nn1c(COc2ccccc2)nnc1SCC(=O)c1cccs1 +CC(C)c1ccc(C2CC2C(=O)NCC(C)(C)C(N)=O)cc1 +Cc1ccccc1C(=O)Nc1cc2c3c(c1)C(C)C(=O)N3CCC2 +Cn1nc(CC(C)(C)C)cc1NC(=O)Cc1cccc(O)c1 +CCCS(=O)(=O)NCc1nnc2n1CCCCC2 +Cc1cccc(OCCNC(=O)C2CCCN(C(=O)C3CC3)C2)c1 +C1=NC2=NC=NC2C(N2CCN(Cc3cccs3)CC2)=N1 +O=C(NCCCS(=O)(=O)c1ccccc1)NCc1cccs1 +c1ccc(-n2nc(C3CCOC3)nc2-c2n[nH]c3c2CCC3)cc1 +CCn1nc(-c2ccccc2CN2CCOCC2)nc1N(C)C +O=C1CCCc2ccc(NC(=O)N3CCc4cc(F)ccc4C3)cc21 +O=C(CNCc1ccccn1)c1ccc2c(c1)CCN2 +CCc1onc(C)c1NC(=O)CSc1cc(C)ccc1C +COc1ccccc1NC(=O)NCCc1nc(C)oc1C +Cc1noc(C)c1CCC(=O)N1CCN(Cc2ccccc2)CC1C +CCCN(CC(=O)OCC)C(=O)c1ccc(Br)cc1C +Cc1cccc(-n2nnc(CO)c2Cc2cccs2)c1 +O=C(CCNC(=O)c1ccccc1)NCCN1CCOCC1 +CC(CNC(=O)N1CCC(CC(N)=O)CC1)N(C)c1ccccc1 +CCc1noc(CC)c1CC(=O)N(C)C1(C(=O)OC)CCCCC1 +CC(C)NC(=O)c1cccc(NC(=O)Cc2ccc(F)cc2)c1 +O=C(Nc1cccc(F)c1)C1COc2ccccc2O1 +Cn1nnnc1SCC(=O)NC1CCCCCC1 +Cc1cc(NC(=O)C2CCN(C(=O)c3ccccc3)CC2)no1 +CNC(=O)c1ccc(Cl)c(NCc2cnccn2)c1 +O=C1CSc2ccc(C(=O)NCCNc3ncccn3)cc2N1 +O=C(NCCc1nnc2ccccn12)c1ccc2ncsc2c1 +CCOC(=O)c1c(C2CC2)csc1NC(=O)c1cnccn1 +COc1ccc(NC(=O)c2ccc(NC(=O)c3cc[nH]n3)cc2)cc1 +Cc1ccc2sc(NCCN3CCOCC3)nc2c1C +CNC(=O)c1ccc(N2CCSc3ncccc32)s1 +Cc1ccc2ncn(Cc3nc(-c4ccc(F)cc4)no3)c(=O)c2c1 +Cc1noc(CN(C)Cc2cc(Br)ccc2F)n1 +CCS(=O)(=O)NCCNC(=O)c1ccc2ccccc2c1 +O=C(NCC1CC1)C1CC2OCCN(Cc3ccsc3)C2C1 +COC(=O)c1ccc(C)c(NC(=O)COc2ccccc2)c1 +CC(C)(CNC(=O)Nc1ccccc1S(C)(=O)=O)c1ccncc1 +O=c1ccc(-c2ccccc2)nn1Cc1ccc(-n2cccn2)cc1 +O=C(OCC1CC(=O)N(C2CC2)C1)C1CCCN(C(=O)C2CC2)C1 +Cc1cc(N2CCC(N3CCN(C)C3=O)CC2)nc(N)n1 +Brc1ccc(Cc2cnc3ccnn3c2)cc1 +N#Cc1ccc(OC(=O)Cc2ccc(F)cc2)cc1 +O=C1CCCN1c1ccc(Cl)c(NCc2nnc(C3CC3)o2)c1 +Cc1ccc(C(O)CCCC(=O)N2CCC(C)CC2)c(C)c1 +COC1CCC2OCCN(C(=O)c3cnc4ccc(C)cn34)C2C1 +CCOc1ccccc1OC1CCN(C(=O)NCC2CCCO2)CC1 +Cc1n[nH]c(C)c1S(=O)(=O)Nc1ccc(F)c(F)c1 +O=c1c2ccccc2nnn1CCCOc1ccc(F)cc1 +Cc1ccc(-n2ccnc2)c(C(=O)N(C)Cc2ccc(C)o2)c1 +CCOC(=O)CC1CCCCN1C(=O)OC(C)(C)C +Cn1ncc2c(C(F)F)cc(-c3ccc4c(c3)OCO4)nc21 +CN1CCN(C(=O)CCCc2nc(C3CC3)no2)Cc2ccccc21 +Cc1noc(C)c1CC(=O)NCC#Cc1ccc(C(=O)N(C)C)cc1 +CC(c1ccccc1)N(Cc1cc(=O)n(C)c(=O)n1C)CC1CC1 +CC(=O)Nc1ccc(C#CCNC(=O)NC(C)(C)C)cc1 +COC(=O)c1ccc2c(=O)[nH]c(-c3cccnc3)nc2c1 +c1ccc(CCc2cn(CC3COc4ccccc4O3)nn2)cc1 +CCOc1ccccc1NS(=O)(=O)c1ccccc1F +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccc(-n2ccnc2)nc1 +CN1C(=O)Cc2cc(NC(=O)Nc3c(F)cccc3F)ccc21 +COc1ccc(S(=O)(=O)N(C)CCc2c(C)nn(C)c2C)cc1 +Cc1ccc(SCC(=O)N2CCN(c3ccc(O)cc3)CC2)cc1 +CCc1cc(NCc2c(C)n[nH]c2C)n2nc(C)c(C)c2n1 +COc1ccc(-c2nc(C)c(C(C)NC(=O)NCCCO)s2)cc1 +CCC(C)C(=O)Nc1ccccc1SC(=O)N(C)C +O=C(c1ccc2ncsc2c1)N1CCC(Oc2cccnc2)CC1 +Cc1ccc(NC(=O)CN2C(=O)C(C)Oc3ccccc32)c(O)c1 +CC(C)NC(=O)C1CC(=O)N(C2CCCCC2)C1 +CCc1oc(-c2ccc(OC)c(F)c2)cc1CO +CCNc1nnc(S(=O)(=O)CC(=O)NC2CC2)s1 +Cc1ccccc1-c1cccc(C(=O)N2CCC(CO)C(O)C2)c1 +Cc1ccc(CNc2cnn(CC(F)F)c2)c(Br)c1 +Cc1cc(C(=O)NCCC(=O)N2CC(C)CC(C)C2)n(C)n1 +CCS(=O)(=O)N1CCc2ncnc(C3CCOC3)c2CC1 +CC(C)c1cccc(OCc2cc(N)n(CCO)n2)c1 +CS(=O)(=O)N1CCCC(NC(=O)Nc2ccccn2)C1 +Cc1cc(NC(=O)C2CC2)n(Cc2ccccc2)n1 +CCC(CC)N(CCO)C(=O)c1ccc(OC)cc1 +Cn1ncc2c(=O)n(CC(=O)c3ccc4c(c3)OCCO4)cnc21 +CCCCN(C)c1ncnc(Nc2ccc3c(c2)OCO3)c1N +Cc1nc(-c2ccc(CNC(=O)c3cccc(N(C)C)c3)o2)cs1 +Cc1cc2c(N)cccc2c(C(=O)N2CCC(C(N)=O)CC2)n1 +CC1(C(=O)NCc2ccccc2)CCC(=O)N1Cc1cccc(F)c1 +Cc1cc(=O)oc(C)c1C(=O)NC(C)c1ccccc1F +COCCc1ccc(OCC(=O)Nc2cccc(C#N)c2)cc1 +CCCOc1ccc(CNC(=O)c2cccc3c2OCCO3)cn1 +CNC(=O)Cc1noc(Cc2c[nH]c3ccccc23)n1 +Cc1nnc2ccc(-c3noc(Cc4ccc(F)cc4)n3)cn12 +Cc1nn(C)c(C)c1NC(=O)Cc1ccc2c(c1)CCC2 +C=CCn1c(SCC#N)nnc1C1CCCCC1 +CC1CCCC(NC(=O)c2ccc(NC(=O)NC(C)C)cc2)C1 +CN(C)C(=O)c1cc(NC(=O)c2cc(Cl)c[nH]2)ccc1Cl +Cc1nc(NC2CCC(O)CC2)c2c3c(sc2n1)CCCC3 +CCS(=O)(=O)NC1CCCN(c2ccc(C#N)cc2F)C1 +COC(=O)CC(NC(=O)c1ccc(C)s1)c1cccs1 +Cc1ccc(OCCC(=O)N2CCCC(n3nc(C)nc3C)C2)cc1 +Cn1cc(C(=O)N2CC3(CCN(c4ccccc4)C3)C2)cn1 +O=C(CCc1ccsc1)Nn1cnc2ccccc2c1=O +CC(C)Oc1cc(C(F)(F)F)c(OC2CC2)cn1 +Cn1c(=O)c2c(nc(Sc3ccc(N)cc3)n2C)n(C)c1=O +O=C(Nc1cccc(-c2nnco2)c1)c1cccc(-c2ccoc2)c1 +Cc1ccncc1NC(=O)N1CCc2c(F)cc(F)cc2C1 +CCOC(=O)c1ccc(NC2CCN(C(=O)c3ccco3)CC2)nc1 +CCc1noc(CC)c1CNC(=O)Cc1coc(-c2cccs2)n1 +CN1CCN(C(=O)COc2cccc(Cl)c2)CC1 +CCc1nnsc1C(=O)N1CCC(c2nc(C)no2)CC1 +Clc1ccc(CNc2ccc3nncn3n2)cc1 +CSc1nccc(N2CCN(C(=O)OC(C)(C)C)CC2C)n1 +COc1ccccc1CN(C(=O)c1ccnc2ccccc12)C1CC1 +CS(=O)(=O)c1ccc(NC(=O)N2CCc3sccc3C2)cn1 +Cc1c2c(cc3c4c(c(=O)oc13)CCC4)CN(C1CC1)CO2 +O=C1CC(C2NCCc3c2ccc(Cl)c3Cl)C1 +Cn1c(=O)c2c(ncn2CCNc2ccccc2)n(C)c1=O +COCCNC(=O)c1ccc2ccc(N(C)Cc3ccccc3)n2c1 +O=C(CCNc1ncccn1)N1CCCC1C1CCCC1 +Cc1ccc(C(=O)CSc2nnc(-c3ccco3)o2)cc1 +Cc1noc(CCC(=O)Nc2ccc3oc(C4CC4)nc3c2)n1 +CC(=O)NCCNC(=O)NC1CCSc2ccc(F)cc21 +Nc1cc(C(F)(F)F)ccc1-n1cc(Cl)cn1 +N#Cc1nccnc1NCC(O)c1ccccc1F +CC(C)CC(CO)NC(=O)Cn1cc(N)ccc1=O +O=C(CN1CCOCC1C1CC1)Nc1ccc(F)cc1 +COc1ccc(NC(=O)Cn2c(=O)cnc3ccccc32)cc1Cl +Cc1nc2ncnn2c(C)c1CCC(=O)OCC1CC1 +CCn1ncc(Br)c1C(=O)NCCCOC +Cc1noc(CN(Cc2nc(C)no2)CC2(c3ccccc3)CC2)n1 +CC1Cc2cc(S(=O)(=O)Nc3ccccc3)ccc2N1 +CCc1nc(CNc2cccc3cnccc23)cs1 +CC(NC(=O)c1ccccc1SCc1cscn1)C(N)=O +CC(C)c1sc2nc[nH]c(=O)c2c1Br +COc1c(Cl)cccc1NC(=O)N(C)CC(C)C +O=C(COc1ccccc1-c1ccccc1)NCC1CCCO1 +CN(C)C(=O)CN(C)S(=O)(=O)Cc1c(Cl)cccc1Cl +CN(CCC#N)C(=O)Nc1ccccc1C(=O)N1CCOCC1 +CCCCNC(=O)CSc1nc2ccccc2n(C)c1=O +COc1ccc(OC)c(CSc2nnc(C)s2)c1 +O=C(Cn1cnc2ncccc2c1=O)NCc1ccco1 +Cc1nnc(NC(=O)CN2CCOC(C)C2)s1 +O=C(NCc1ccco1)Nc1cccc(N2CCNC2=O)c1 +Cc1sc2ncnc(SCCCC#N)c2c1C +N#CC1(NC(=O)c2ccc(=O)n(Cc3ccccc3)n2)CCCCC1 +Cc1ccc(S(C)(=O)=O)c(NC(=O)NCC2CC2C)c1 +O=C(Cn1nc(-c2ccco2)ccc1=O)NCCC1=CCCCC1 +CCn1cc(NCc2ccc(OC)c(OC)c2)c(C)n1 +O=C(Cc1ccc(O)cc1)N1CCN(Cc2ccccc2)CC1 +CCOc1ccccc1S(=O)(=O)Oc1ccc2c(c1)ncn2C +CC(C)CC(CNC(=O)c1nccnc1N)N1CCOCC1 +N#CCn1c(C(F)(F)F)nc2ccc(F)c(F)c21 +O=C(CCc1ccc(F)cc1)NCCC(=O)N1CCCCC1 +CN(Cc1cc(Cl)cc(Cl)c1)Cc1cnnn1C +CC1(C)CCCCC1NC(=O)c1scnc1C1CC1 +O=C(NCCc1nccn1C(F)F)c1ccc(-n2cccn2)c(F)c1 +O=C(Nc1ccccc1F)c1ccn(-c2ccc(F)cc2)n1 +Cc1cc(C(=O)CCCC(=O)NC(C)(C)C)ccc1F +Cc1nsc(N2CCN(Cc3c[nH]nc3-c3ccc(C)o3)CC2)n1 +CC(c1ccccn1)N(C)CC(=O)OCc1ccccc1 +Cc1cc(-c2ccc(S(=O)(=O)N(C)Cc3ccco3)s2)[nH]n1 +COCCNC(=O)c1ccc(N(C)S(=O)(=O)c2ccccc2)cc1 +COC(=O)N1CCCC(C(=O)Nc2cc(OC)ccc2F)C1 +O=C(NCc1ccccc1)c1nnc(CSc2ncn[nH]2)s1 +CC(NC(=O)NC1COc2ccccc21)c1cccs1 +Cc1cc(NC(=O)CCc2ncc(-c3ccccc3Cl)o2)no1 +CC(=O)Nc1ccc(CC(=O)NCCc2cccc(F)c2)cc1 +Cc1csc(C2CCCCN2C(=O)Cn2cnnn2)n1 +CC1CCN(C(=O)Cn2ncc3c(Cl)cccc32)CC1 +CCC(=O)NCC1(c2ccc(Cl)cc2)CCOCC1 +O=C(c1ccc(O)cc1)c1ccc2c(c1)OCCCO2 +CCC1c2ccccc2CCN1C(=O)c1cccc(C#N)c1 +NC(=O)CCCNC(=O)c1csc(Cc2ccccc2)n1 +Cc1ccc(C(=O)NCC2Cc3ccccc32)c(=O)[nH]1 +Nc1c(Cl)ccc2c(NCCOCCO)nccc12 +Cc1noc(C(C)C)c1C(=O)N1CCN(C(=O)c2ccccc2)CC1 +O=C(CNC(=O)c1cc(-c2ccccc2)on1)NCc1ccsc1 +O=C(NCc1cc[nH]n1)c1cc(Br)c2c(c1)OCCO2 +CCN(CC)C(=O)Nc1cccc(NC(=O)C2CC2)c1 +COc1cccc2c1OCC(NC(=O)C1CCOCC1)C2 +O=C(OCc1cncc(Br)c1)c1ccn2cncc2c1 +CC(NC(N)=O)C(=O)N1CCN(C(=O)Cc2ccccc2F)CC1 +CCCNC(=O)C(C)N1CCN(CC(F)F)CC1 +O=S(=O)(Nc1ccc(F)cc1)N1CCCCCC1 +O=C(NCCNC(=O)c1ccccc1Cl)c1cnn[nH]1 +Cn1nnc2ccc(-c3noc(-c4cccs4)n3)cc21 +CCCOc1ccc(C(O)c2cccs2)cc1OC +CNC(=O)COC(=O)c1ccc(F)c(COC)c1 +NC(=O)COc1ccc(Cl)cc1S(N)(=O)=O +CC(C)n1c2ccccc2n2c(SCC(N)=O)nnc12 +OCCOc1cnc2ccc(Br)cc2n1 +Cc1nnc(NC(=O)CN2C(=O)COc3ccc(Cl)cc32)s1 +COc1ccc(C(=O)N(C)c2ccc(N)cc2N)cc1 +Cc1cn2c3c(=O)n(C)c(=O)n(C)c3nc2n1C(C)c1ccccc1 +COc1cccc(-c2n[nH]cc2CNCCc2nnc3n2CCC3)c1 +CC(C)CN1CCN(C(=O)c2cccc(F)c2F)CCC1=O +Nc1ccc2sc(OCCN3CCOCC3)nc2c1 +O=C(NCCc1ccccn1)c1cccc(-n2cccc2)c1 +O=C(c1cnccn1)N1CC2COCC2(COc2ncccc2F)C1 +CCCCOC(=O)c1cc2c(=O)c3cc(F)ccc3oc2nc1C +CCc1nn(C)c(OC)c1CN1CCOC(C(N)=O)C1 +CC(=O)Nc1nc(C(=O)OC(C)CC(C)C)cs1 +CC(C)CCNC(=O)C(C)Nc1ccc(N2CCCC2=O)cc1 +Cc1cc(NC(=O)Cc2ccccc2)ccc1NC(=O)c1ccco1 +Cc1nc(NC(=O)NCc2c(F)cccc2F)nn1C(C)C +CC(=O)N1CCCC1C(=O)Nc1cnn(-c2ccccc2Cl)c1 +Cc1ccc(NC(=O)c2c(-c3ccccn3)cnnc2N)cc1 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)c1cccc(OC)c1F +CN(C)c1ccc(C(=O)NCC2CCN(c3ccccc3)C2)cn1 +COc1cccc(SCC(=O)NC(C)c2ccc(C#N)cc2)c1 +Cc1ccc(C(C)NC(=O)Cc2ccccc2F)o1 +O=C(CCc1nc2ccccc2[nH]c1=O)N1Cc2ccccc2C(O)C1 +CC(C)NC(=O)N1CCc2c(c(C(=O)N3CCCCC3)nn2C)C1 +CC1CCCC(C)N1C(=O)N(CCO)CCCO +CCn1nc(C)c(CCNC(=O)c2cc(CC(C)C)no2)c1C +Cn1nncc1CN1Cc2ccccc2-c2ccccc2C1 +CC1(CNC(=O)C2(c3ccc(F)cc3F)CCOCC2)CCC1 +CCn1cc(C(=O)N2CC(C)OC(C)C2)c2ccccc21 +CCN(C(=O)COc1ccccc1C(N)=O)C1CCCCC1 +CCc1noc(CC)c1CNC(=O)c1ccccc1F +Cc1csc(=O)n1Cc1sccc1Br +Cc1ccc(C(=O)N2CCN(Cc3ccn(C)c3)CC2)cc1 +Cc1cc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)[nH]n1 +COc1ccc(CN(C)C(=O)Nc2ccccc2)cc1F +Cc1cc(=O)[nH]c(SCC(=O)N(C)Cc2ccccc2)n1 +CC1CCC(OC(=O)c2c[nH]c(=O)c(Cl)c2)CC1 +CC1(C)CCN(C(=O)NCc2cc(=O)[nH]c3ccccc23)C1 +CCN(CC)c1ncc(C(=O)N2CCCCC2C)c(N)n1 +CCOc1ccc(-n2c(C)cn3c4c(=O)[nH]c(=O)n(C)c4nc23)cc1 +CCC(=O)N1CCCCC1C(=O)N1CC2CCC1C2 +CC(=O)Nc1ccc(S(=O)(=O)Nc2cccc(C)c2)cc1Cl +Cn1nnnc1SC(C(=O)N1CCCCC1)c1ccccc1 +COc1ccc(-c2nn3c(=O)cc(-c4ccc(C)nc4)[nH]c3c2C)cc1 +Cn1c(-c2cnco2)nc2c(Br)cccc21 +CC(NCC(F)(F)F)(C(N)=O)c1ccc(Br)cc1 +N#CC1(C(=O)NC2CCN(C(=O)c3ccoc3)CC2)CCCC1 +C#CCN1CCCCC1C(=O)N1CCN(Cc2noc(CC)n2)CC1 +N#Cc1ccc(NC(=O)CCC2CCCO2)cc1Cl +CCCc1nc(C)c(C(=O)NCCNC(=O)c2ccoc2)s1 +Cc1nccn1-c1ncccc1NC(=O)c1ccco1 +c1ccc(-c2nnc(C3CCN(Cc4ccccn4)C3)o2)cc1 +COc1cc(Br)cnc1N(C)C(=O)OC(C)(C)C +Cc1noc(C)c1CC(=O)N1CCN(CC2(CO)COC2)CC1 +CN(C)C(=O)N1CCC(C(=O)NC2CCCCC2O)CC1 +Cc1ccc(-c2nc(N)n(C(=O)c3ccco3)n2)cc1 +CCc1noc(C)c1C(=O)NCC1CCN(c2ccc(Cl)cc2)C1 +CCOCCNC(=O)NCc1ccccc1-n1cccn1 +Cc1cc(C)c(CNC(=O)NCc2ccsc2)c(=O)[nH]1 +COC(=O)Nc1cc(NC(=O)c2cccc(C)c2)ccc1F +Cc1csc(NC(=O)CCS(=O)(=O)N2CCNCC2)n1 +CCOc1ccccc1-n1nnnc1SCc1csc(CC)n1 +CC1CCCCC1NC(=O)N1CCCC(NS(C)(=O)=O)C1 +COCCNS(=O)(=O)c1ccc(Cl)c(C)c1 +COc1ccc(OC(C)C(=O)N=c2[nH]c3ccccc3[nH]2)cc1 +CCOCC1CCCN(C(=O)Nc2ccc3oc(C4CC4)nc3c2)C1 +CCc1nnc(C(=O)Nc2cccc(C(=O)NCCC(C)C)c2)s1 +CNC(=O)c1cnc(C=CC2=Cc3cc(Cl)ccc3OC2)s1 +FC(F)(F)c1csc(N2CCN(Cc3ccccn3)CC2)n1 +CC(C)NC(=O)CN1C(=O)COc2cc(Br)ccc21 +CC(=O)Nc1nc(C(=O)NCCC(=O)Nc2cccc(C)n2)cs1 +NC(=O)C1CCN(C(=O)c2cc(-c3cccnc3)on2)c2ccccc21 +CC(CNC(=O)CC1CCOCC1)c1nc(-c2ccccc2)no1 +COc1ccc(-c2cc(C(C)=O)c(C)[nH]2)c(OC)c1C +COc1cccc(OC)c1OC1CCN(C(=O)C2CCOC2)CC1 +CCOc1ccc(NC(=O)Cc2nc3scc(C)c3c(=O)[nH]2)cc1 +CC(C)(C)n1ccnc1SC1CCN(CC(F)(F)F)C1=O +CCOCc1ccc(NC(=O)N2CCN(C(CC)CO)CC2)cc1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCCc1ccccc1 +Cc1c(C(C)NC(=O)c2cc3c(s2)CCC(C)C3)cnn1C +Cc1ccc(CC(=O)Nc2cccc(OCCn3cccn3)c2)cn1 +COCCNS(=O)(=O)c1ccc2c3c(cccc13)C(=O)N2C +CC(=O)NCCNC(=O)c1cc(-c2cccs2)n[nH]1 +CCCn1c(SCC(=O)N(C)Cc2ccc(F)cc2)n[nH]c1=O +CCCCn1ccc2c(cnc3nc(-c4cccnc4)nn32)c1=O +Nc1ccc(Br)c(C(F)(F)F)c1N +Cc1cc2ncn(CC(=O)Nc3ccc(F)cc3)c2cc1C +CCc1onc(C)c1NC(=O)NCCc1ccc(OC)cc1Cl +Cc1[nH]c(=O)ccc1C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +CC(C)CCC(=O)N1CC(C(=O)N2CCCCC2)Oc2ccccc21 +O=C(NCc1cccnc1)c1ccc(Cl)cc1O +Cc1cc(N)nc(SCC(=O)c2ccc(Cl)cc2)n1 +COc1ccccc1Oc1ccc(NC(=O)NCc2ccccn2)cc1 +CS(=O)(=O)Nc1nn(Cc2ccccc2)cc1Cl +Cc1c(N)cccc1NC(=O)CCOC1CCC(C)CC1 +CN(C)C(=O)N1Cc2cnn(C)c2C(COCC2CC2)C1 +Cc1nn(C)c(C)c1NC(=O)Cc1ccc(F)cc1 +Cc1cccnc1CNC(=O)CCC(=O)c1ccc2c(c1)OCCO2 +Cc1ccc(C)c(N(C)Cc2nc3ccsc3c(=O)[nH]2)c1 +CCCNC(=O)NCCOc1ccc2c(c1)CCC2 +O=C(Cn1cnnn1)NCC1CCN(c2ccccc2)C1 +CCN(Cc1ccccc1)C(=O)CCC(O)c1ccccc1 +Cn1c(N2CCCN(S(C)(=O)=O)CC2)c(C#N)c(=O)n(C)c1=O +CCCNC(=O)c1cccc(C(=O)Nc2ccc3oc(=O)[nH]c3c2)c1 +COC(=O)C(C)CN(C)S(=O)(=O)c1cc(C)ccc1F +Cc1ccc(C(=O)C2CCN(C(=O)NCC(=O)N(C)C)CC2)cc1 +Cc1nc(NC(=O)c2ccc(-c3cscn3)cc2)n[nH]1 +O=C(COC(=O)c1cnccn1)Nc1ccccc1Oc1ccccc1 +Cc1cccc(NC2=Nc3cc(N)ccc3OC2)c1C +CC(C)Cc1cc(Cn2cc(-c3cncnc3)nn2)no1 +O=C(CCCNC(=O)C1CC1)Nc1cccc(-n2cnnc2)c1 +CCN(Cc1ccc(Cl)c(Cl)c1)C(=O)NCCC(=O)N(C)C +O=C(NCc1ccnc(-n2ccnc2)c1)C1CC1c1cccc(F)c1 +Cc1c(NS(C)(=O)=O)cccc1C(=O)N(C)Cc1ccccc1 +Cc1cc(C(=O)NC(C)c2nnc3n2CCC3)on1 +CCn1c(C2CC(=O)N(C(C)(C)C)C2)nc2ccccc21 +CCc1nnc(NC(=O)CCc2ccccc2OC)s1 +CN(C)C(=O)CC(C#N)c1ccc2c(c1)OCCO2 +COCCN1CCOC2CN(S(=O)(=O)c3cccnc3)CC2C1 +Cc1ccc(C)c(OCC(=O)N2CCN(C(=O)C3CCCO3)CC2)c1 +c1ccc(-c2cc(Cn3nnc(-c4ccsc4)n3)no2)cc1 +Cc1ccc(CNC(=O)COC(=O)c2ccc(C#N)cc2)cc1 +O=C(COc1ccc(F)cc1)NCc1nc(-c2ccccc2)no1 +CCN(CC(=O)Nc1cc(Cl)ccc1C)C(=O)c1ccncc1 +Cc1noc(C)c1CC(=O)Nc1cc(Cl)ccc1Cl +O=S(=O)(NC1COc2ccccc21)c1cnn(-c2ccccc2)c1 +CCNC(=O)C(C)Sc1nnnn1-c1ccc(C)cc1 +CCN(CCO)c1ncnc(Oc2cccc3ccc(C)nc23)c1N +COC(=O)N(C)c1ccc(NC(=O)Nc2cccc(C#N)c2)cc1 +O=C(CC1(Cn2cnnn2)CCCCC1)N1CCOCC1 +O=C(Cc1cccs1)N1CCC(O)(c2ccccn2)CC1 +Cc1nn2c(CCc3cccc(N)c3)nnc2s1 +COc1ccc(S(=O)(=O)N2CCN(CCCO)CC2)cc1 +Cc1cc(OC(C)C(=O)Nc2ccc(C(N)=O)cc2)ccc1Cl +Cc1ccn(-c2ccc(NCc3ccnn3C)nn2)n1 +CCc1cnc(N)nc1NC1CCCN(C(C)=O)C1 +COc1ccc(F)cc1C(=O)N(C)CC(=O)N(C)C +Cc1nc(CC(=O)Nc2cc(Cl)cc(Cl)c2)cs1 +CC(C)c1nnnn1CC(=O)NCC(C)(O)c1ccc(F)cc1 +C=C(C)COC(=O)CCC(=O)c1ccc(F)cc1 +COc1cc(F)ccc1NC(=O)CCn1nnc2ccccc2c1=O +CCc1nnc(COC(=O)c2snc(-c3ccccc3)c2N)o1 +CSc1nc(N)nc(SCC(=O)NCc2ccccc2)c1C#N +O=C(NCCc1ccc(F)cc1)c1cccc(-c2cn[nH]c2)c1 +Cc1noc(CCCC(=O)N(C)C(C)C2CC2)n1 +O=C(CNC(=O)c1cc(F)cc(F)c1)NCCCN1CCCC1=O +COCCn1nc(C)c(CNC(=O)Nc2cnccc2C)c1C +CCCC1CN(C(=O)c2cccc3c2OCCO3)CCO1 +COc1ccc(-n2cc(CNC(=O)c3cc(OC)ccn3)nn2)cc1 +N#CCCNc1ncc(-c2cc3ccccc3s2)cn1 +Cc1noc(COCC(=O)NCC(=O)NC(C)(C)C)n1 +Cc1ccc2nc(C(F)(F)F)nc(Sc3nnnn3C)c2c1 +COC(=O)C(C)(C)NC(=O)c1cnc(Cc2ccc(F)cc2)s1 +COCCN(Cc1cccs1)C(=O)c1ccn(C)c(=O)c1 +NC(=O)CCCN1CCNc2cc(Cl)c(Cl)cc21 +O=C(NC1CC1)C1(c2cc(-c3ccco3)on2)CC1 +CCCn1nnc(-c2ccc(OC)c(OCC)c2)n1 +COC(=O)c1ccccc1NC(=O)c1nonc1N +CCCC(=O)Nc1cc(C(=O)N2CCOCC2)ccc1C +COCc1ncc(C(=O)Nc2nnc(C)s2)c(N)n1 +CCC(=O)Nc1cccc(C(=O)Nc2cc(C)cc3cccnc23)c1 +CC(Sc1ccccn1)C(=O)N(Cc1cccs1)C1CC1 +c1cncc(-c2ncnc3c2CCN(Cc2ccco2)CC3)c1 +COCCNc1nnc(S(=O)(=O)Cc2cccc(F)c2)s1 +O=C(NCc1ccc(F)cc1)c1cn(-c2cccc(F)c2)nn1 +CN(CC1CCCCO1)C(=O)Nc1ccc(-c2csnn2)cc1 +N#CC1CN(C(=O)c2cc[nH]n2)CCN1Cc1ccccc1 +COc1c(Cl)cccc1NC(=O)Cn1c(=O)oc2ccccc21 +Cc1cnc(-c2cccc(NC(=O)c3cnn(C)c3-n3cccc3)c2)o1 +CCc1nc(CNCC(c2ccc(C)o2)N2CCOCC2)cs1 +Cn1cc(Cl)c(C2CCCCCN2S(=O)(=O)N2CCCC2)n1 +COC(=O)c1ccc2c(=O)[nH]c(CSc3nncs3)nc2c1 +Cc1ccc(NC(=O)C(C)(C)C)cc1NCc1nnc(C2CC2)o1 +Cc1ccc(NC(=O)NC(C(N)=O)C(C)(C)C)cc1C(=O)NC(C)C +Cc1ccc(-c2nc(C(=O)NCCc3cccs3)no2)cc1 +CNC(=O)COc1ccc(C(=O)N(C)C)cc1OC +NC(=O)Cn1cnc2scc(-c3ccc(F)cc3)c2c1=O +CC(CNS(=O)(=O)N1CCOCC1)N1CCc2ccccc21 +Cc1noc(C)c1S(=O)(=O)N1Cc2ccccc2CC1C(N)=O +Oc1cccc(C2CN(Cc3cccc(Cl)c3F)CCO2)c1 +CC(C)N(CC1CC1)C(=O)c1cccc(Br)c1 +CCOC(=O)C=C1CN(Cc2ccccc2)CCN1C +COC(C)C(=O)NCc1ccc(CN2CCc3ccccc32)cc1 +NC(=O)C1CCCN1C(=O)c1ccc(CSc2ccccc2)cc1 +C#CCN1CCN(Cc2nc3c(F)cccc3n2CC)CC1 +Cn1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cn1 +COc1cccc(-c2c[nH]nc2C2CCCN2C(=O)CNC(C)=O)c1 +COC(=O)Nc1ccc(NC(=O)CCc2c(C)n[nH]c2C)cc1 +O=C(NCC(O)c1cccc(C(F)(F)F)c1)c1ccccc1 +Cc1ccnc(NC(=O)c2ccc3cccc(O)c3n2)c1 +CCn1cnnc1-c1cccc(NC(=O)c2ccccn2)c1 +CCOc1nc(N(C)Cc2cc(C)on2)ccc1N +CC(Sc1ccccc1)C(=O)Nc1nc(-c2ccc[nH]2)cs1 +COc1cccc(OC)c1OCc1ccc(-n2cccn2)cc1 +Cc1cc(CN(C)C(=O)C2(c3cccc(F)c3)CCC2)no1 +COC(=O)c1cccc(Cc2nc(-c3ccc(C#N)cn3)no2)c1 +O=C(NCCc1ccccn1)N1CCc2ccc(Cl)cc2C1 +CCOc1cc(C)ccc1NCC(=O)Nc1cc(C)on1 +COCCN1CCN(C(=O)c2cccnc2N(C)C)CC1=O +O=C(Nc1cccc(-c2nnco2)c1)C1CCCC1 +Cc1cc(N2CCC(C(N)=O)C2)n2nc(C(F)(F)F)nc2n1 +O=C(NCCN1CCOCC1)Nc1ccccc1Br +O=C(C1CC2C(CCN2Cc2nccs2)O1)N1CCOCC1 +Cc1sc2c(=O)n(C3CC3)cnc2c1C(=O)NC1CCCC1 +Cc1cn2nc(NCC3(c4ccc(F)cc4)CCOCC3)sc2n1 +CC1CN(CCCNC(=O)N(C)CCc2ccccn2)CC(C)O1 +Cc1cc(NC(=O)C2(c3ccccc3)CC2)ccn1 +COCCCn1c(C)cc(N2CCOCC2)c(C#N)c1=O +Nc1nonc1C(=O)Nc1ccc(OC(F)F)cc1 +CCc1onc(C)c1NC(=O)Cc1coc(-c2ccc(Cl)cc2)n1 +Cc1cc(S(=O)(=O)Nc2ccncc2)c(C)cc1Br +COc1ccc(NC(=O)c2ocnc2C)cc1OC +Cc1ccc(C(=O)Nc2ccccc2C(=O)N2CCC(C)CC2)cc1 +COc1nc(C(C)C)nc(NCCc2ccc(F)cc2)c1N +Cc1ccc(O)c(C(=O)NCc2ccnc(-n3ccnc3)c2)c1 +COc1ccc(Cn2nc(-c3cccc(OC)c3)ccc2=O)cc1 +Cc1sc(-c2ccno2)cc1S(=O)(=O)N1CCCCCC1 +COc1ccc(C)cc1S(=O)(=O)N1CC(c2ccncc2)C1 +CCOC(=O)c1cc(C#N)c(N2CCCCC2)nc1C(F)(F)F +Cc1noc(C)c1CCCNC(=O)c1cc2cccc(C)c2n1C +CN(Cc1ccc(O)cc1)S(=O)(=O)CC1CCCCC1 +Cc1ccccc1NC(=O)c1nc2ncc(Br)cn2n1 +COc1ccc(C(=O)NCc2ccon2)cc1F +Cc1cc(C)n(Cc2ccc(C(=O)Nc3cnc4n3CCCC4)cc2)n1 +Cc1cc(C)n(C(C)C(=O)Nc2cc(Cl)cc(Cl)c2)c(=O)n1 +COc1cc(S(=O)(=O)Oc2ccccn2)c(OC)cc1Cl +CCc1[nH]c(SCC(=O)Nc2ccccc2C(=O)OC)nc1C +NC(=O)Cn1cc(Nc2cnc3ccccc3n2)cn1 +Cc1cc(C)c2cc(C(=O)NCCN3CCOCC3)[nH]c2c1 +OCc1nnn(CCCc2ccccc2)c1-c1ccccc1 +Cc1ccc(CO)cc1NC(=O)COc1cccc(Cl)c1 +CNC(=O)C1COC(=O)N1Cc1cccc(O)c1 +N#Cc1nncn1CC(=O)Nc1ccc(F)c(F)c1 +Cc1csc(NC(=O)C2COc3ccccc3O2)n1 +Cc1ccc(CC(=O)N2CCCC(CNC(=O)C(C)C)C2)cc1 +COC(=O)Cc1c(C)c2cc(Cl)c(OCC(N)=O)cc2oc1=O +CCC(=O)N1CCCN(C(=O)Nc2cc(Cl)ccc2F)CC1 +COC(=O)c1c(C)[nH]c(C(=O)OCc2ccccc2F)c1C +CN(C)C(=O)c1ccc(C(=O)Nc2ccc3[nH]ncc3c2)cc1 +Cc1ccccc1OCCNC(=O)NCC1CC1C +CC(NC(=O)CCc1ccc(O)cc1)c1cnn(C)c1 +CC(CC#N)N(C)C(=O)Nc1ccccc1OC(F)(F)F +CC(C)S(=O)(=O)N(Cc1ccsc1)C1CC1 +CS(=O)(=O)N1C=Cc2ccccc2C1c1c[nH]c2ccccc12 +CCC(C#N)Oc1cccc(CNC(=O)c2cccc3c2ccn3C)c1 +COc1ccc(CC(=O)Nc2ccc3oc(C)nc3c2)c(OC)c1 +COc1ccccc1CNC(=O)Cn1c(C)nc2ccccc21 +COc1cccc(NC(=O)NCc2nc(-c3ccccc3)n[nH]2)c1 +COc1ccc(C(C#N)CC(=O)Nc2ccccc2F)cc1 +CN(C)C(=O)c1cccc(S(=O)(=O)NCCc2cnn(C)c2)c1 +Cc1ccc(CCC(=O)NCc2nc3ccccc3n2C)cc1 +Cc1ccc(NC(=O)C(C)C)cc1NCC(=O)N1CCC(C)CC1 +NC(=O)Cc1ccc(NC(=O)CCn2cnc3ccccc32)cc1 +CS(=O)(=O)NC(c1ccc(F)cc1)C1CCCO1 +O=C(CNC(=O)c1ccsc1)NC1CC1c1cccc(Cl)c1 +CCC(C)(NC(=O)CCn1c(=O)[nH]c(=O)c2ccccc21)C(=O)OC +O=C(c1cc(-c2ccccc2)on1)N1CCCCC1Cn1cccn1 +Cc1ccc(OCC(=O)Nc2ccccc2O)cc1C +CCN(C(=O)Nc1ccc(OCCOC)nc1)C1CCCCC1 +CCOc1ccc(-c2cc(C(=O)OC)c3c(C)noc3n2)cc1 +CC(C)c1nc(Cn2c(-c3cccnc3)noc2=O)no1 +COCCN1C(=O)c2oc3ccccc3c(=O)c2C1c1ccc(C)cc1 +CC(C)C(=O)Nc1ccc(Sc2nncs2)cc1 +CCc1ccc(-c2cnn(C)c(=O)c2CC#N)cc1 +CC(C)CN1C(=O)CCc2cc(NS(=O)(=O)C(C)C)ccc21 +CC(C)(C)OC(=O)N1CCN(c2cc(=O)[nH]c(N)n2)CC1 +COc1cnn(-c2ccc(Cl)c(Cl)c2)c(=O)c1Cl +N#CCCn1cnc2c(Cl)cc(Cl)cc2c1=O +OCc1nnn(-c2nccs2)c1-c1ccncc1 +C=CCNC(=O)Nc1ccc(NC(=O)c2cccc(C)c2)cc1 +CCc1cccc(C)c1NC(=O)Cn1cc2c(n1)CCCCC2 +COc1cccc(CCC(=O)Nc2cccc(C(C)=O)c2)c1 +CS(=O)(=O)c1ccc(F)c(NC(=O)CC2CCCC2)c1 +COc1ccc(CC(C)CNC(=O)c2c(C)nn(C)c2C)cc1 +Cc1ccc(-c2csc3ncnc(OCC(=O)NC(C)C)c23)cc1 +FC(F)Oc1cccc2c1C(c1cc[nH]n1)NCC2 +COc1cc(N2CCCC3(CCN(c4cnn(C)c4)C3=O)C2)ncn1 +CC(NC(=O)N1CCN(c2ccc(Cl)cn2)CC1)c1ccncc1 +COc1ccccc1OCc1nn2c(-c3cc(C)n[nH]3)nnc2s1 +COCCOc1ccc(NC(=O)Nc2cn[nH]c2)cn1 +CC(C)C(=O)NCc1ccnc(Oc2ccccc2)c1 +Cc1cc(C)n(CC2CCCN2C(=O)C2CCOC2)n1 +C=CCSc1nnc(NCc2ccc(F)cc2)s1 +O=C(Cn1cnnn1)N1Cc2cnn(Cc3ccc(F)cc3)c2C1 +CC(C)N(Cc1ccccc1)C(=O)c1ccc(CO)cc1 +CN(C)C(=O)Cc1ccc(NC(=O)c2cccn(C)c2=O)cc1 +Nc1cccc(-c2csc(-c3cc[nH]c(=O)c3)n2)c1 +C=CCn1c(SCC(=O)OC)nnc1C(F)(F)F +CC(O)(c1cccc(Br)c1)C(F)(F)F +COc1ccc(CN2CCN(c3nc(C)cc(C)n3)CC2)cc1 +NC(=O)CC1CCN(C(=O)C2(c3ccc(F)cc3)CCC2)CC1 +Cc1cc(C2CCCN2C(=O)c2cccc(Cn3cccn3)c2)no1 +OC(c1ccc(C(F)(F)F)cc1)c1cccnc1 +COc1ccc(-c2nn(CCO)c(=O)[nH]c2=O)c(OC)c1OC +Cc1ccnc(NC(=O)c2c[nH]nc2-c2ccc3c(c2)OCCO3)c1 +CCOCCCC(=O)Nc1cccc(-n2cnnn2)c1 +Cc1ccc(NC(=O)C2CCCN2C(=O)c2cccs2)cc1C +COC(=O)CCN(CC(C)C)C(=O)c1cnc2ccc(C)cn12 +Cc1nc(C)c(C(C)Nc2cc(F)ccc2N)s1 +CNC(=O)C1CCN(C(=O)C2CC(c3ccccc3)C2)CC1 +CC(NC(=O)COCC1CC1)c1ccc(S(N)(=O)=O)cc1 +COCC(C)NC(=O)CSc1nc2ccccc2c(=O)n1C(C)C +CCCNC(=O)Cn1c(C(C)NC(C)=O)nc2ccccc21 +CCS(=O)(=O)NCc1ccc(OC(C)C)nc1 +O=C(COCc1cc(-c2ccc3c(c2)OCO3)on1)NC1CCCC1 +CCCc1noc(Cn2cnc3c(cnn3-c3ccccc3)c2=O)n1 +CN(C)S(=O)(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +CN(CCO)C(=O)c1nc(-c2ccccc2)n(-c2ccccc2)n1 +CCn1cc(C(=O)OCc2ccc(F)cc2)c(=O)c2ccc(C)nc21 +CCCNC(=O)c1ccc(C)c(S(=O)(=O)N2CCCCC2)c1 +CCCn1nccc1C(=O)NC(CC)c1ccc(C)cc1 +Cc1csc(C2CN(Cc3coc(-c4cccs4)n3)CCO2)n1 +CCOC(=O)Nc1ccc(NC(=O)N(C)CC2CC2)cc1 +CCNC(=O)C(C)NC(=O)C(Sc1ccccc1)c1ccccc1 +Cn1cnc(CNC(=O)NCCCCC(C)(C)C)n1 +CC=CC=CC1NCCc2cc(OC)c(OC)cc21 +c1ncc2c(n1)CN(Cc1csc(-c3ccsc3)n1)CC2 +N#CCSc1ccccc1NC(=O)CNc1cccc(C#N)c1 +Cc1c(C(=O)Nc2ccc(Cn3cncn3)cc2)oc2c(C)cccc12 +Cc1cc(C)n(CCN2CCN(C(=O)C3CCCCC3)CC2)n1 +CCN(CC)C(=O)c1nccc2c(N)ccc(F)c12 +Cc1ccc(F)cc1NC(=O)CCCNC(=O)c1ccco1 +COCCOc1cccc(CNC(=O)N2CCC(C)CC2C)c1 +CC(NC(=O)Cn1cnc2ccc(F)cc2c1=O)c1cccnc1 +Cc1cccc(CS(=O)(=O)N2CCCC2c2nc(C)no2)c1 +CC(C#N)NC(=O)c1sccc1Br +Cc1cc(N)c2ccn(S(=O)(=O)c3ccccc3)c2n1 +CCOC(=O)c1cn(CC(O)c2cccc(C#N)c2)nn1 +NC(=O)N1CCC(C(=O)Nc2ccc3nc(C4CC4)sc3c2)CC1 +CCOc1cc(C)ccc1NC(=O)Cc1cn2ccsc2n1 +CN(CC(=O)NC(C#N)c1ccc(C(C)(C)C)cc1)S(C)(=O)=O +COc1ccccc1-c1nc(C)nc(N2CCOCC2)c1N +O=C(NCCc1ccccn1)NC(Cc1ccccc1)C(F)(F)F +CC(Nc1ccccc1SC(F)F)C(=O)NC1CC1 +CC(C)(C)c1nnc(SCc2ccccn2)n1N +CNC(C#N)CCOc1cccc(Br)c1 +CCC(C(=O)Nc1cccnc1)n1cnc2ccccc2c1=O +Cc1cc(C)c(C)c(OC(=O)C2CCN(C(=O)c3ccoc3)CC2)c1 +O=C(CC(F)(F)F)N1CCc2onc(Cn3cccn3)c2C1 +CCc1ccc(C(=O)N2CCCCC2CNC(N)=O)cc1 +CCC(CO)NC(=O)NC1CCN(C(C)=O)CC1 +Cc1ccc(N)cc1NC(=O)CCN(C)c1ccccc1 +CC(Nc1nc2cc(C(F)(F)F)ccc2s1)C(N)=O +CCC(=O)N1CCc2cc(C(=O)OCCNc3cccnn3)ccc21 +Cc1ccccc1C(=O)NCCC(=O)Nc1cccc(-c2ccn[nH]2)c1 +CN(C1CCC(CO)CC1)S(=O)(=O)Cc1cccc2cccnc12 +O=C(NCc1ccnc(OC2CCC2)c1)N1CCC2(CCOC2)C1 +Cc1ccc(N2CC(C(=O)N3CC(C)OC(C)C3)CC2=O)c(C)c1 +CN(CCc1ccccn1)c1ncccc1CNC(=O)C1CCCO1 +Cc1cccc(C(=O)NCC2(O)CCOc3ccccc32)c1 +Cc1cc(C(=O)NCCNC(=O)c2cccnc2)c2cccc(C)c2n1 +CC(=O)NS(=O)(=O)c1ccc(C)c(N2CCCC2=O)c1C +CC(=O)c1c(C)[nH]c(C(=O)Cn2ncc(Cl)c(Cl)c2=O)c1C +Cc1ccc(-n2nnnc2CNC(=O)Nc2ccccc2F)cc1C +Cc1cc(Oc2ncccc2C#N)ccc1NC(=O)c1ccnnc1 +CNC(=O)c1ccc(OC)c(NC(=O)N(C)C(C)c2cccnc2)c1 +CCn1nnc2cc(C(=O)OCCNc3cccnn3)ccc21 +COC(=O)CNC(=O)c1cc2sccc2n1Cc1cccc(F)c1 +Cc1noc(C)c1COc1ncnc2ccc(Br)cc12 +COc1ccc(NC(=O)COC(=O)c2ccc(C)nc2)c(OC)c1 +Cc1cc(C)cc(COc2cccc(C(=O)NCCO)c2)c1 +COCC(=O)NC1CN(c2nc(C)c(C)c(C)c2C#N)CC1C1CC1 +CC(NC(=O)c1cn(C)nc1C(F)(F)F)c1ccccc1Cl +COc1ccc2oc(C(=O)c3ccncc3)nc2c1 +CCc1ccc(C(=O)Nc2ccccc2C(=O)NC)cc1 +C=CCNC(C#N)c1cccc(Br)c1 +N#Cc1cc(F)cc(C(=O)NCC2CCCOC2)c1 +COC(=O)CCCN(C)C(=O)c1c[nH]c2cccc(F)c12 +COc1ccc(C(=O)N2CCCC(CO)C2)cc1OC +COc1ccccc1CN1CCN(c2ccccc2N)CC1 +Cc1ccc(C)c(NC(=O)c2cc(S(N)(=O)=O)c(C)o2)c1 +CCC(CO)Nc1ccc(NC(=O)c2ccccc2Cl)cn1 +COc1cccc(CNC(=O)c2cc(-c3csc(C)n3)cn2C)c1 +CCOC(=O)C(O)Cc1cnn(Cc2ccccc2)c1 +CCc1cc(C(=O)Nc2cc(Cl)ccc2O)no1 +Cc1cc(NC(=O)Cc2ccc(Cl)cc2)ccn1 +Cc1nc(C2CCN(C(=O)CO)CC2)cc(C(F)(F)F)n1 +CCN(CC)C(=O)c1ccccc1NC(=O)CC1CCCC1 +CC(C)CNC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +Cc1nc2ccc(C(=O)N3CC(O)C3)cc2nc1C +c1cncc(OCc2nc(C3CC3)nn2-c2cccc3cccnc23)c1 +Cc1ccc(C(=O)N(C)C)cc1NCc1c(C)noc1C +COC(=O)CC1CCCCN1C(=O)c1c(C)noc1C +Cn1cccc1C(=O)NCc1ccc2ccccc2c1 +CCN1CCN(S(=O)(=O)c2cc3c4c(c2)CCN4C(=O)CC3)CC1 +CC(=O)NCCNC(=O)c1ccc(=O)n(-c2ccc(F)cc2)n1 +CC(Sc1nc2ncccn2n1)C(=O)NCc1ccccc1Cl +O=C(NCc1ncc(-c2ccccc2)o1)c1ccc(=O)[nH]c1 +Cc1nc(C)c(CC(=O)N2CCCC2c2ccccc2C)s1 +Cc1ccc(Sc2ccc(C(=O)N3CCCC3)cn2)c(C)c1 +CC(CO)Nc1ccc(Br)cc1C#N +Cc1cc(NC(=O)C2CCCO2)n(-c2ccccc2C(F)(F)F)n1 +CCOc1ccc(C(O)c2cccs2)c2cccnc12 +O=C(NCCOc1cccc(Cl)c1)NCc1nnc2ccccn12 +CCOC(=O)c1c(NC(=O)c2ccccn2)sc(C(C)=O)c1C +CC(NC(=O)CCSc1ccccn1)c1cnn(C)c1 +Cc1nc(C(=O)Nc2nc(C)c(C)s2)c(-c2ccccc2)s1 +CC(C)Oc1ncc(C(=O)N2CCCC2c2ccncc2)cc1Cl +CS(=O)(=O)N1CCN(c2ccc(-c3ccccc3)nn2)CC1 +O=C(CCNC(=O)C1CCCC1)Nc1ccc2ccccc2n1 +CC(NC(=O)Nc1nncs1)c1nc(-c2ccccc2)cs1 +O=C1NCCc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc21 +CC1CCCC(C)N1C(=O)COC(=O)CCc1ccccc1 +O=C(NCC(O)c1cccc(F)c1)c1ccccc1Br +C#CCN1CCN(C(=O)NC(C)c2nnnn2-c2ccccc2)CC1 +Cc1cc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c(C)s1 +Cn1nnnc1SCC(=O)Nc1ccccc1N +Cc1c(-c2ccccn2)nc(N)c(C#N)c1-c1ccc(-c2cc[nH]n2)o1 +O=C(Cc1ccc[nH]1)N1CCN(c2ncnc3sccc23)CC1 +COc1ccc(Cl)cc1S(=O)(=O)NCc1ccsc1 +CCCC(=O)N1CCCCC1CCN1CCOCC1 +CC1CCN(C(=O)NCC(=O)N(C)CC(F)(F)F)C1 +CC(CC(=O)NCCNC(=O)c1ccccc1)c1ccccc1 +Fc1ccccc1N1CCN(Cc2nnc(-c3ccccc3)o2)CC1 +Cc1ncc(CNc2ccccc2-n2ccnn2)s1 +CCOC(=O)c1sc2sc(C(=O)OCC)c(N)c2c1N +COc1cc(C)c(-c2nc3scc(N)n3n2)cc1OC +N#Cc1ccc(C(N)c2nnc(C3CCC3)o2)c(F)c1 +COc1ncccc1C(=O)Nc1cnn(CC(=O)N(C)C)c1 +CCOc1cc(CO)cc2c1OC(C)C(=O)N2C(C)C +N#Cc1ccc(C(=O)N2CC(c3nc(-c4ccco4)no3)C2)cc1 +COc1ccnc(NCc2cccc(CN3CCOCC3)c2)n1 +COc1cccc2c1CCN(Cc1ccc(Cl)cc1)C2=O +CC(C)COC(=O)CCNc1n[nH]c(=O)[nH]c1=O +O=C(C1CCC1)N1CCC(c2ccnc3nccn23)C1 +O=C(c1ccc(F)cc1)N1CCCC1c1nc2ccccc2[nH]1 +O=C(OC1CCCC1)c1ccc(NC(=O)C2COCCO2)cc1 +COC(=O)C1CCN(C(=O)Cn2ccccc2=O)CC1 +CN(CCc1ccc(F)cc1)Cc1cc(C#N)cs1 +CCNC(=O)N1CCN(C(C)C(=O)Nc2ccc(Cl)cn2)CC1 +Nc1nc(CSc2ccccc2)ncc1C(=O)NC1CC1 +NC(=O)Nc1ccccc1SCC(F)(F)F +Nc1cc(F)c(NCc2ccc(Cl)cc2)c(F)c1 +CN(C)C(=O)N1CCCC(C(=O)NCCc2cccs2)C1 +COC(=O)N1CCN(c2cc(C)nc(N)n2)CC1 +CCN(CCO)C(=O)Nc1ccc(NC(C)=O)cc1C(F)(F)F +Cn1c(=O)n(C)c2cc(-c3nc4c([nH]3)CC(C)(C)CNC4=O)ccc21 +COC(=O)CC1CCCCN1C(=O)c1ccc(C)cc1 +CCNC(=O)COc1ccc(C)cc1C(=O)OC +Cc1occc1C(=O)N1CCC(c2nc3ccccc3[nH]2)CC1 +Cc1ccc(C)c(C(=O)CCC(=O)NCC(C)(C)c2ccncc2)c1 +O=C(CSc1nc(C2CC2)n(-c2ccccc2)n1)c1ccccc1 +O=C(Nc1nc2c(s1)COCC2)c1cc(=O)c2ccccc2o1 +CNC(=O)c1cccc(NCC(=O)NC(C)(C#N)C2CC2)c1C +O=C(NCCn1nc2ccccn2c1=O)C1(c2ccc(F)cc2)CC1 +Cc1c(C(=O)Nc2cccc3cnccc23)nc2cc(Cl)ccn12 +CNS(=O)(=O)c1ccc(OCCCC(C)C)c(N)c1 +OC(CN1CCN(c2ccccc2F)CC1)c1c[nH]c2ccccc12 +CN(C)S(=O)(=O)c1cc(F)ccc1Br +COc1ccc(Nc2nccc3c2ncn3C)cc1 +Cc1ccc(OCCNC(=O)C2CCCN2S(C)(=O)=O)cc1 +CC(=O)NC(C)C(=O)NCCCN1CC(C)OC(C)C1 +COc1ccc(CCNC(=O)c2cccc(Cn3cccn3)c2)cc1 +COc1ccc(CNC(=O)c2ccccc2-n2cnnn2)cc1OC +CN(C)c1ccc(C(=O)N2CCCC2c2cccc(F)c2)cn1 +CCOCCC(=O)Nc1cc(-n2cnnn2)ccc1F +Cc1ccnn1-c1ccc(C(=O)Nc2c[nH]ccc2=O)cc1 +CCC(C)(NC(=O)Nc1nnc2ccccn12)c1nc(C)cs1 +Cc1cc(C)n2cc(CNc3cccc(NC(=O)C(C)C)c3)nc2n1 +COc1cc(C)ccc1NC(=O)c1cc(C)nc2c1cnn2C(C)C +Cc1ccc(C)c(OCCCn2ccnc2)c1Cl +Cn1cc(NC(=O)c2cccnc2SCc2ccc(F)cc2)cn1 +Cc1cc(C2CCCN2C(=O)c2ccnc(-n3ccnc3)c2)no1 +CCc1cc(CNC(=O)c2cccn(CC(=O)N(C)C)c2=O)on1 +Cc1cnc(-c2nc(-c3ccc(N)cc3)cs2)cn1 +COc1ccnc(NC(=O)c2c[nH]cc2-c2ccc(F)cc2)c1 +CC(C)Cc1ccc(S(=O)(=O)N(C)c2ccccc2C(N)=O)cc1 +CC(C)(C)CCNC(=O)NCC(O)c1cccc(F)c1 +CCN(CC)C(=O)c1c(C)nc(C(C)(C)C)[nH]c1=O +CNC(=O)NCC(=O)N1CCN(C(=O)Cc2ccccc2F)CC1 +CCCC(NC(N)=O)C(=O)NCc1cn(-c2ccccc2)nn1 +CC(=O)Nc1cc(NC(=O)NCc2ccnn2C)ccc1C +C=CCOc1cccc(NC(=O)c2cnn(-c3ccncc3)c2C)c1 +CC(C)(C)NC(=O)CNC(=O)Nc1ccncc1 +COCC(=O)N1CCN(C(=O)CCc2ccc(OC)cc2)CC1 +CC(=O)c1cccc(NC(C(=O)NC2CC2)c2ccccc2)c1 +CC(Nc1ccc2nnc(C(F)(F)F)n2n1)c1ccccc1F +CCOC(=O)N1CCN(CC(C)c2ccccc2)CC1 +NC(=O)COC(=O)COc1ccc(-c2ccccc2)cc1Cl +Cc1cc(NC(=O)c2ccnc(NC3CC3)c2)[nH]n1 +Cc1ccccc1OCC(O)CSc1nnnn1C1CC1 +COc1ccc(Cl)cc1CNC(=O)c1ccc(C)nc1 +Nc1cc(N)cc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)c1 +CCOc1cc(NCc2ccccc2F)nc(C(C)C)n1 +Cc1ccc2cccc(C(=O)Nc3ccc(N4CCCCC4)cn3)c2n1 +CNc1ccc(Cl)c(C(=O)N(CCC#N)C(C)C)n1 +Cc1noc2ncc(C(=O)Nc3cccc(-c4cn[nH]c4)c3)cc12 +CC(=O)c1cccc(OC(=O)C2CCN(C(=O)N(C)C)CC2)c1 +Cn1c(=O)c(COc2ccc(C#N)cc2)nc2ccccc21 +CCCCC1C(=O)NCCN1C(=O)Nc1cccnc1OC +c1ccc(-c2nnn(Cc3noc(-c4ccoc4)n3)n2)cc1 +Cn1c(=O)[nH]c(=O)c2c1nc(NCc1ccccc1)n2CCC#N +Cc1nn(-c2ccccc2)c(C)c1C(=O)N1CC(C)OC(C)C1 +CC(C)CC(=O)Nc1ccc(-c2csc(N3CCOCC3)n2)cc1 +Cc1nn(Cc2ccccc2)c2sc(C(=O)Nc3ccccn3)cc12 +N#Cc1ccc(CN2CCc3c(nc[nH]c3=O)C2)cc1 +CCNc1c(NC(=O)c2ccccc2C)c(=O)oc2ccccc12 +CCN(Cc1ccoc1)S(=O)(=O)c1cc(F)ccc1Cl +CC(C)CCSc1nc2ncn(C)c2c(=O)[nH]1 +CN(C)C(=O)CN(C)S(=O)(=O)c1cc2c(cc1Cl)OCCO2 +Cc1cc(C)n(CC2CCCN2C(=O)c2ccc3c(c2)nnn3C)n1 +COCCS(=O)(=O)N1CCC(NC(=O)C2CCCO2)CC1 +COc1ccccc1C(=O)n1cc(C#N)c2ccccc21 +Cc1ccc(N2CCN(C(=O)Nc3ccc4c(c3)OCO4)CC2)nn1 +O=C(NCc1cccnc1)c1csc(Nc2cccnc2)n1 +Cc1nc2c(C)cccc2cc1C(=O)N1CCC(CO)C(O)C1 +COc1cc(C(C)=O)ccc1OCC(=O)N(C)c1ccc(F)cc1 +Cc1ccc(S(=O)(=O)N(C)C)cc1C(=O)NC1CC1 +CCOC(=O)c1ccc2nc(C)cc(NC(=O)c3ccncc3)c2c1 +COc1ccc2c(c1)CCN2C(=O)CCn1nc2ccccn2c1=O +Cc1occc1-c1nnc(SCc2nc(-c3cccs3)no2)o1 +O=C(COCC1CC1)N1CCc2ccc(O)cc2C1 +CCCCc1nnc(NC(=O)NC(C)c2c(C)noc2C)s1 +NC(C(=O)NCCC1CCCCC1)c1ccccc1 +Cc1cc(C2CCCCCN2C(=O)c2ccncc2)no1 +CC1CCCN(C(=O)CCCNC(=O)C(C)(C)C)C1 +Cc1cc(C)cc(NC(=O)Nc2cccc(Cn3cccnc3=O)c2)c1 +CCCNC(=O)c1c(C)nn(-c2ccccc2)c1C +Cc1cc(C)nc(NC(=O)c2cccc(C)c2O)n1 +CCOc1ccccc1C(=O)OCC(=O)NC(C)(C)C +CCC(=O)Nc1cccc(NC(=O)c2cscn2)c1 +O=C1CCCN1c1cccc(OCc2nc(-c3ccsc3)no2)c1 +CCS(=O)(=O)N1CCC(C(=O)NC2CCCCC2C)CC1 +Cc1cc(C)cc(C(=O)OCC(=O)NC(C)(C)C)c1 +O=C1OC2c3ccccc3C(=O)N2c2ccc(O)cc21 +COc1ccc(NC(=O)NCC(C)(C)N2CCOCC2)cc1F +COc1ccc(Cn2ncc(Br)c2N)cc1 +CN(C)c1nc(COc2cccc(-n3cnnn3)c2)ns1 +O=C(COC1CCCCC1)Nc1cccc(CO)c1 +Nc1cc(=O)[nH]c(SCC(=O)N(C2=CCCCC2)C2CC2)n1 +Cn1cnc(CNC(=O)NCc2ccc(-n3cccn3)cc2)n1 +Cc1noc(COc2ccc3c(C)cc(=O)oc3c2)n1 +CNC(=O)COc1cccc(OCc2ccc(F)cc2F)c1 +CC(C)CCNC(=O)CCc1cn2cc(N)ccc2n1 +Cc1cc(C)c(NC(=O)c2c3c(nn2C)CCCC3)c(C)c1 +Cc1cccc(N2CCN(c3cnnc(=O)[nH]3)CC2)c1C +O=C1c2ccccc2C(Nc2ccccc2)N1c1cccnc1 +O=C(COC(=O)CSc1ccc2c(c1)CCC2)NC1CC1 +Cn1c(C(=O)NCCCn2cccn2)cc2c(Cl)cccc21 +O=C(c1scc2c1CCCC2)N1CC(O)C(N2CCOCC2)C1 +Cc1ccc(C(=O)n2nc(-c3ccccc3)nc2N)cc1 +COc1cc(C(C)C)c(OC)cc1NCC(N)=O +O=C(COc1ccccc1)NCC1CC(=O)N(c2ccc(F)cc2)C1 +CCCC(C)C(=O)NC(c1nnc2ccccn12)C(C)C +Cc1noc(C2CCCN(C(=O)c3c(C)nn(C)c3C)C2)n1 +Cc1cc2nc(-c3ccco3)c(CO)n2cc1Br +CN(Cc1cccc(C#N)c1)C(=O)Cn1nnc(-c2ccccc2)n1 +COCCN(CCC#N)Cc1cccc(Cl)c1 +N#CC1(NC(=O)COc2ncnc3sc4c(c23)CCC4)CCCC1 +CC(O)(CC(=O)NC1CCN(c2ccccc2)CC1)c1ccccc1 +CCS(=O)(=O)N1CCCc2cc(F)cc(F)c21 +Cc1cc(Cn2cnc3sc(C)c(-c4ccccc4)c3c2=O)on1 +C#CCOC(=O)CSc1nncn1-c1ccc(C)c(C)c1 +CC(=O)c1ccc(NC(=O)NCCCOC2CCOCC2)cc1C +Cc1cc(S(=O)(=O)N(C)C)cc(NC(=O)c2ccc[nH]2)c1C +Cc1cc(C)c(NC(=O)CSc2nc(=O)[nH]c(C)c2C#N)c(C)c1 +Cc1ccnc(C(NC(=O)c2cc[nH]c2C)C2CC2)n1 +N#CCOc1ccc(NC(=O)CCCc2cccs2)cc1 +Cc1ccc2cc(C(=O)N3CC(C(N)=O)CCC3C)[nH]c2c1 +Cc1cc(CNC(=O)Nc2ccc(Cn3cccn3)cc2)no1 +CCn1c(=O)c(C)nc2cc(C(=O)NC(C)C3CC3)ccc21 +COCCNC(=O)Nc1cc(NC(=O)Nc2ccccc2)ccc1C +Cc1nc(-c2cccc(N3CC(C(=O)NC4CC4)CC3=O)c2)no1 +Cc1cc(=O)oc2cc(Oc3coc4cc(O)ccc4c3=O)ccc12 +Cc1ccc(F)c(N2CCC(C(=O)NCc3ccccc3F)C2=O)c1 +Cc1ncsc1CNc1ccc(Br)cc1 +CCN1CC(C(=O)N2CCN(CCn3cccc3)CC2)CCC1=O +O=C(NCc1ccccn1)NC12CC3CC(CC(C3)C1)C2 +CC1CN(C(=O)C(C)Oc2ccc(F)cc2Cl)CC(C)O1 +O=C(NCCCO)c1cccc(OCC2CCCO2)c1 +COc1ccc(CCC(=O)OCC2CCC(=O)N2)cc1 +COc1cccc(-c2nc(N(C)C)c(C#N)cc2C)c1 +CCOC(=O)C(C)Sc1nc2c(c(=O)[nH]c(=O)n2C)n1C(C)C +O=C(c1ncoc1-c1ccco1)N1CCOc2ncccc21 +COc1ccc(OS(=O)(=O)c2cccc(C(C)=O)c2)cc1 +CCOc1cc2nc(-c3cccc(N)c3)n(C)c2cc1OCC +COc1ccc(Cl)cc1NC(=O)Nc1ncccc1C +C#CCN(Cc1ccc(C)cc1)C(=O)Nc1nncs1 +CC(C)CCN(C)C(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1 +CN(C)C(=O)c1cccc(CSc2nc(-c3cccs3)n[nH]2)c1 +Cn1cc(N2CCCC(N3CCN(C(=O)C(C)(C)C)CC3)C2=O)cn1 +CNC(=O)c1cccc(CCNC(=O)NCc2ccnn2C)c1 +COC(=O)c1sc2nc(C)nc(NCc3cc[nH]n3)c2c1C +O=C(Nc1ccc2c(c1)C(=O)OC2)c1ccccc1Cl +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)OCC1C(C)(C)C1(C)C +CCSc1cc(N2CCN(c3ccccc3F)CC2)ncn1 +CC1NC(=O)COC12CCN(C(=O)c1ccno1)CC2 +Nc1ccc2oc(C(=O)NCc3ccccn3)cc(=O)c2c1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)c1ccccc1Cl +C=CCNC(=O)Cn1cnc2c([nH]c3cc(OC)c(OC)cc32)c1=O +N#CCCn1cc(CN2CCOC(C#N)C2)c(-c2ccccc2)n1 +CCN(Cc1ccoc1)C(=O)NCC(OC)c1ccccc1 +COc1cn(-c2ccc(F)cc2)nc1C(=O)Nc1ccccc1F +CCC(C)NC(=O)c1onc(-c2ccccn2)c1N +Cn1cc(S(=O)(=O)NCC(=O)NC2CCCCCC2)cn1 +CC(C)C(NC(=O)c1c(F)cccc1F)C(=O)OCC(F)F +N#CCCCSc1nnc(C2CC2)n1-c1ccccc1 +Cc1oc(C)c(S(N)(=O)=O)c1C(=O)NC(C)c1cccc(F)c1 +Cc1ccc(CNC(=O)Nc2ccc3c(c2)C(=O)CCC3)s1 +COc1cccc(CN2CCc3nc4ncccc4cc3C2)c1 +COc1ccc2nc(NC(=O)NCCO)sc2c1 +Nc1cc(NC(=O)c2cccc(O)c2)ccc1Cl +COc1ccccc1CC(=O)Nc1ccccc1O +CCCN(CC1CCCCO1)C(=O)c1cc(=O)n(C)c2ccccc12 +Nc1cc(S(=O)(=O)NCC2CCOC2)ccn1 +C=CCNC(=O)C1CCC(=O)N1C1OC(=O)c2ccccc21 +CCOC(=O)C(Cc1nc2cc(OC)ccc2s1)NC +CCOc1ccc(F)c(C(=O)Nc2cn[nH]c2)c1F +COc1ncccc1CNC(=O)Nc1ccc(C)cc1C +COc1ccc(OC)c2sc(NC(=O)c3cnccn3)nc12 +CN1CC(c2cc(=O)n3ncc(-c4ccc(F)cc4)c3[nH]2)CC1=O +COc1ccc(CC(=O)Nc2nccs2)c(OC)c1 +Cc1csc(CNC(=O)c2ccc(-n3nc(C)cc3C)cc2)n1 +Cc1cc(C(=O)NC2CCCCCC2)c2c(C)noc2n1 +CCOc1ccccc1C(=O)NCc1nnc2n1CCCC2 +COc1cccc2cc(C(C)NC(=O)c3cccnc3)oc12 +O=C(NCc1ccccc1OC(F)(F)F)c1ccc[nH]c1=O +CCn1cc(NS(=O)(=O)Cc2cccc(C)c2)ccc1=O +Cc1ccccc1CNS(=O)(=O)c1c(C)noc1C +CC(=O)Nc1ccc(CNc2cccc(CN(C)C(C)=O)c2)cc1 +CCCC(NC(=O)c1n[nH]c2ccccc12)c1nnc2ccccn12 +O=C(CCOc1cccc(Cl)c1)Nc1cccc(-c2nc[nH]n2)c1 +O=C(Cc1c(Cl)cccc1Cl)c1cccnc1 +O=C(c1cccc(OCC(F)F)n1)N1CCOc2ccccc21 +NC(=O)c1ccccc1NC(=O)c1cc2c([nH]c1=O)CCCC2 +O=C(OCCN1CCCC1=O)c1ccc(C(F)(F)F)nc1 +Cc1ccccc1CC(C)(C)NC(=O)NCc1cnn(C)c1 +CCOCC(=O)N(Cc1cnc2ccccn12)C1CC1 +CCc1ccccc1N1CC(C(=O)NCc2cccnc2)CC1=O +CC(=O)Nc1ccc(Cl)c(NC(=O)NCc2ccccn2)c1 +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +Cc1nnc(-c2ccc(CCOc3ccc(F)cc3)cc2)o1 +CCCCN(C)C(=O)C1CN(C(=O)c2ccc3c(c2)OCO3)C1 +CC(C(=O)N1CCOC(CO)C1)n1nnc(-c2ccccc2)n1 +O=C(Cc1ccccc1F)OCCNC(=O)c1ccncc1 +CCOC(=O)COc1cc(C)cc2oc(=O)c(C)c(C)c12 +Cc1oc(NC(=O)C(C)n2c(N)nnc2SCC#N)c(C#N)c1C +CC(C)(C)CC1CCCN1C(=O)CCN1CCCC1=O +O=C(NCc1ccncc1)Nc1cc(Cl)ccc1Cl +COCC(=O)Nc1ncn(Cc2ccc(Br)cc2)n1 +CC(=O)Nc1ccc(C(=O)Nc2ccccc2C)cc1 +Cc1cccc(C(=O)Nc2cc(C(=O)N(C)C)ccc2C)n1 +COc1ccc(NC(=O)C2CCC2)c2cccnc12 +Cc1cc(N(C)C)cc(C)c1NC(=O)NCc1ncc[nH]1 +COc1ncnc2c1CCN(C(=O)NCc1ccccc1)C2 +Nc1ccc(NC(=O)COCC2CC2)c(Br)c1 +Cc1cc(COC(=O)CCC(=O)N2CC(=O)Nc3ccccc32)on1 +O=C1OCCC1Sc1nnnn1Cc1cccs1 +CC(=O)N1CCC(NC(=O)c2cccnc2OCC(F)F)C1 +CC(C)OCCCNC(=O)c1sc2ncccc2c1-n1cccc1 +Cc1ccc(C(=O)Nc2ccc(S(C)(=O)=O)cc2C)cc1 +Cc1oc(C(=O)NC2CCCCC2C)cc1S(N)(=O)=O +OC1CCN(c2ncc(Cl)c3ccccc23)CC1 +CC(C)(C)CC(=O)Nc1cc(C#N)ccc1Cl +CC1CCCC(OC(=O)C2CC(=O)N(Cc3ccco3)C2)C1 +O=C(Nc1cccc(NC(=O)N(CCO)C2CC2)c1)c1cccs1 +Cc1cc(C)n(-c2ccc(C(=O)N3CCNC(=O)C3)cn2)n1 +CSc1ccccc1NC(=O)CSc1nc(C)cs1 +CCOc1ccccc1C=Cc1nc(-c2ccc(C#N)cn2)no1 +Nc1ccc2nc(-c3ccc4c(c3)CCO4)[nH]c2c1 +CCCC1CN(C(=O)Nc2ccccc2-n2nc(C)cc2C)CCO1 +CCc1ccc(CNc2nc(N)n(-c3ccccc3)n2)cc1 +CCc1ccc2nc(NC(=O)N3CCCC3CO)sc2c1 +CC(O)CCNc1ncc(C(F)(F)F)cc1Cl +O=C(CN1CCN(c2ccc(F)cc2)C1=O)Nc1ccccc1 +COC(=O)c1ccc(NC(=O)c2cc(O)c(OC)cn2)cc1 +N#Cc1ccc(COC(=O)CCC(=O)c2ccc(F)cc2)cc1 +Cc1cc(C(C)NC(=O)NCc2ccnc(-n3cccn3)c2)c(C)o1 +CNC(=O)NCC(=O)NCc1ccc(OC)cc1C(F)(F)F +COCC1(O)CCN(C(=O)c2ccc3nnnn3c2)CC1(C)C +COc1ccc(CC(=O)Nc2cccc(SC)c2)c(OC)c1OC +COc1cccc(NC(=O)C(C)Oc2cccc(OC)c2)c1 +CCN1C(=O)c2ccccc2C(=O)C2(C)CN(C(=O)C3CC3)CC12 +CCN(CC)c1c(C#N)c(=O)oc2c(C)cc(C)cc12 +CCN(CC)C(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +CCOc1ccc(NC(=O)C2CCCO2)c(N)c1 +COCCOc1ncccc1CNC(=O)c1ccc(C)[nH]c1=O +O=C(NC1CCSc2c(F)cccc21)c1n[nH]c(=O)[nH]1 +COc1cc(NC(=O)CCc2nc3ccccc3s2)cc(OC)c1 +COc1ccccc1COC(=O)Cc1ccc(-n2cnnn2)cc1 +COc1ccc(CNC(=O)CN(C)c2ccccc2)cc1 +Cc1cc(F)ccc1OC(=O)c1cnc(C2CCCO2)s1 +Cc1nc(C)c(CCNC(=O)NCCCN2CCCCC2=O)s1 +Cc1ccc(OC(C)C(=O)N2CCC2)c(Br)c1 +COCCN(C)c1ccc(-n2nc(C)cc2C)cn1 +Cc1ccc2c(c1)CCCN2C(=O)CN(C)Cc1snnc1C +CN(C)C(=O)CCC(=O)c1ccc2ccccc2c1 +COc1cc(S(=O)(=O)NCC(C)O)c(OC)cc1Cl +O=C(NCC1CC=CCC1)Nc1nc(C(F)(F)F)cs1 +COc1cccc(NC2CCN(c3ccc(C#N)cn3)CC2)c1 +CC(=O)NC(C)C(=O)NCc1coc(-c2cccs2)n1 +CC(CO)NC(=O)c1sccc1S(=O)(=O)N1CCCC1 +COc1nc2ccc3nc(NC(=O)c4ncc[nH]4)sc3c2s1 +COc1cccc(CNC(=O)Nc2cc(F)ccc2Cl)c1OC +Cc1cccc(C)c1NC(=O)CNCc1cccc(Cl)c1 +CCCCN(CCO)C(=O)Nc1cc(C)ccc1OC +CCn1ccc(C(=O)Nc2nnc(-c3ccc(F)cc3F)o2)n1 +Cc1nnc2cc(N3CCN(Cc4cccs4)CC3)cnn12 +O=C(Nc1ccccc1-n1cnnn1)c1cccc(C(F)(F)F)c1 +CC1CCCN(c2ncnc(Nc3ccc4c(c3)OCO4)c2N)C1 +CC(C)NC(=O)N1CCCC1C(=O)NCC(C)(C)c1ccncc1 +COc1ccccc1NC(=O)c1c(Cl)cnn1C +CC(C)Nc1nc(-c2cccnc2)nc2ccccc12 +COc1cc(C2NC(=O)c3ccc(Cl)cc3N2)cc2c1OCO2 +NS(=O)(=O)c1ccccc1NC(=O)c1cnccn1 +CC(=O)Nc1cccc(Nc2ccc(N)cc2N)c1 +CCCN(C)C(=O)Nc1cnn(Cc2ccccc2)c1 +Cc1csc(NC(=O)c2ccc(Br)c(F)c2)n1 +CCC(C)NC(=O)CSc1nnc(C)n1-c1ccccc1 +Cn1c(=O)c2ccc(C(=O)OCC(F)(F)F)nc2n(C)c1=O +CCC(CO)NS(=O)(=O)c1ccc(Cl)c(OC)c1 +COc1ccc(S(=O)(=O)NCC(O)c2ccsc2)cc1OC +Cc1cc(C)c2nc(NC(=O)c3ccc(C#N)c(C)n3)sc2c1 +CN(Cc1cccs1)S(=O)(=O)c1cc(N)ccc1F +NC(=O)c1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1 +Cn1cc(C(=O)Nc2ccc(CN3CCOCC3)cc2)cn1 +CCOC(=O)c1cc2sc(N3CCOCC3)nc2s1 +COc1cc(OC)c2nc(-c3ccoc3)cc(C)c2c1 +Cc1ccc(S(=O)(=O)CCCn2cnc(C#N)c2C#N)cc1 +Cc1cc(C(=O)Nc2ccc3cc[nH]c3c2)c2c(C)nn(C)c2n1 +CN(C)c1nc(N)nc(Cn2cnc3cc(Cl)ccc3c2=O)n1 +CC(C#N)NS(=O)(=O)c1ccccc1C(C)(C)C +COc1cccc(NC(=O)Cc2ccc(-c3csc(C)n3)cc2)c1 +CC(C)(C)C(=O)Nc1nnc(-c2ccccc2Cl)o1 +CCCc1nc(COc2cccc(OC)c2)sc1CO +O=C1CCSc2ccc(C(=O)NCCc3ccccn3)cc2N1 +NS(=O)(=O)NCC(c1ccccc1)c1ccccc1 +COCC1CN(C(=O)NCc2ccccc2C)CCO1 +Cc1cc(NC(=O)CN2CCN(c3ccccc3O)CC2)on1 +O=C(NCCc1ccccc1Cl)Nc1cn[nH]c1 +CN(CCOCC1CC1)C(=O)c1cnn(-c2ccc(F)cc2)n1 +c1ccc(Cn2nnnc2SCc2cccc3c2OCCO3)cc1 +Cc1ccc(C(=O)Nc2ccc(N(C)C)nc2)cc1-n1cccc1 +COc1cc(CC(C)(CO)CO)cc(OC)c1OC +COCCNC(=O)N1CCCC(c2cc(C(N)=O)[nH]n2)C1 +Cc1ccc2ncc(C(=O)Nc3cc(C(N)=O)ccc3Cl)n2c1 +O=C(NCC1CCCO1)c1ccccc1SCc1ccco1 +CC(C)N(C(=O)c1cc(C#N)cn1C)c1ccc(Br)cn1 +O=C(NCC1CCCCC1)C1CC2CCCC(C1)C2=O +CCCN(CC(=O)OC)S(=O)(=O)c1cc(F)ccc1C +CN(Cc1ccc2c(c1)OCCO2)c1ncnc2c1cnn2C +CCN(CC)S(=O)(=O)c1ccc(C)c(NC(C)=O)c1 +CC(C)(C)OC(=O)Cn1cc(C(F)(F)F)ccc1=O +O=C(NCCN1CCOCC1)c1cccc(-c2ccoc2)c1 +CC(C)(C)C(=O)NCCCN1CCOC(c2ccccc2)C1 +Cc1ccc(NC(=O)c2ccncc2)cc1S(=O)(=O)N(C)C +Cn1nnnc1COc1cccc(C(=O)NCc2ccccc2)c1 +CC(C)(O)C#Cc1ccc(C(=O)NCc2ccccc2F)s1 +CCOc1ccc(NC(=O)c2ncn(-c3ccccc3)n2)cc1 +O=c1c2sccc2ncn1Cc1cc(-c2ccccc2)on1 +Cc1nc(Cn2c(=O)oc3cc(Br)ccc32)cs1 +COc1cccc(CC(=O)N2CCN(Cc3ccncc3)CC2)c1 +CCSc1ccc(Cl)cc1NC(=O)NCC(C)C(=O)OC +O=C(NCCc1c[nH]c(=O)[nH]c1=O)c1csc(-c2cccs2)n1 +COC(=O)c1ccc(Cn2c(N)nnc2SCC#N)cc1 +Cc1nnc(NC(=O)c2ccc(OCc3ccccc3)cc2)s1 +COc1ccc(C(=O)Nc2cc(C)nn2C(C)C)cc1OC +O=c1[nH]c(Nc2c(F)cccc2F)nc2c1CCCC2 +COC(=O)CCC(=O)N(C)C(C)c1ccc(C)cc1 +COC(=O)C(NC(=O)CC1c2ccccc2CCN1C(C)=O)C(C)C +Nc1ccc2c(c1)N(Cc1cccc(Cl)c1)C(=O)CO2 +Cc1c(N)cccc1NC(=O)CCOCC1CCCCO1 +Nc1cc(F)cc2c(C(=O)NCc3ccccn3)nccc12 +COc1ccc(F)cc1-c1c(C(F)(F)F)noc1N +COCCNC(=O)c1cccc(NC(=O)c2ccc(Cl)cc2)c1 +CC(C)C(NC(=O)C1CCN(S(C)(=O)=O)CC1)C(C)C +Cc1occc1CN(C)C(=O)C(C)(C)c1ccccc1 +CCc1cccc(C)c1N1C(=O)C(C)CS1(=O)=O +CCc1nc(C)c(C(C)OC(=O)c2ccc(S(C)=O)cc2)s1 +O=C(COc1ccc(F)cc1Cl)Nc1ncccn1 +Cc1nn(-c2ccccc2)c(C)c1N1CCN(C(=O)C2CC2)CC1 +Cc1cnn(C2CN(CC=Cc3ccccc3)C2)c1 +O=C(c1ccccn1)N1CCC(OCc2ccccc2)CC1 +O=C(Cn1ccccc1=O)NCc1ccc(Cl)cc1Cl +CCS(=O)(=O)N1CCC(C(=O)NCCCn2ccnc2)CC1 +CC1CC(C)CN(C(=O)CSc2cc(=O)n(C)c3ccccc23)C1 +CCC1(CNC(=O)c2cccc(NC(=O)c3cccs3)c2)CC1 +Cc1cccc(OCc2ncc(C(N)=O)c(N)n2)c1C +N#CCn1c(C(Cl)(Cl)Cl)nc2cc(F)c(F)cc21 +CCC(NC(=O)c1ccc(=O)n(C)n1)c1cccc(Cl)c1 +Brc1ccccc1-c1nnc(C2CC2)o1 +CC1COCCN1C(=O)c1ccnc(OC2CCC2)c1 +COc1ccccc1NC(=O)N1CCC(CO)CC1 +Cc1ccc(-c2cc(-c3nc(C4CCOC4)no3)[nH]n2)s1 +COC(=O)Cn1ccn(-c2cc(F)ccc2C)c(=O)c1=O +CS(=O)(=O)NCC(=O)NCCc1ccccc1F +COc1cccc(-c2noc(Cn3cnc4cc(F)c(F)cc43)n2)c1 +Cn1c(=O)c2sccc2n2c(CN3CCOC(C)(C)C3)nnc12 +Cc1sc(-c2ccco2)nc1C(=O)N(C)CC(=O)N1CCOCC1 +CC(c1cccc(Cl)c1)N(C)C(=O)c1ccc(=O)[nH]c1 +CC1CC(C)CN(C(=O)c2cc(-c3ccccc3)n[nH]2)C1 +OCCc1csc(COc2cc(Cl)ccc2Cl)n1 +CCN(CC)C(=O)c1cn(-c2ccccc2Br)nn1 +COc1cc(C(=O)NC(C)c2ccccn2)cc(OC)c1OC +Cc1ccccc1NC(=O)NCC(=O)NC(C)(C)C +Cc1cccc(OCCNc2nn3cc(C)nc3s2)c1 +CCC(CC)n1ccc(C(=O)Nc2nc(-c3ccccn3)cs2)n1 +Cc1nc(C(C)Nc2nc3c(s2)c(C)nn3C)n[nH]1 +COC(=O)c1cccc(C(=O)Nc2ccc(Br)cn2)c1 +Cc1nc(C(C)C)n(-c2ccc3c(c2)CNCC3)n1 +CCc1nc(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)c[nH]1 +CC(NC(=O)Nc1ncc(-c2ccccc2)s1)c1nc[nH]n1 +O=C(Nc1ccc2c(c1)COC2)c1n[nH]c2c1CCC2 +CN(Cc1cc(-c2cccnc2)no1)C(=O)Cc1ccsc1 +COCC(C)NC(=O)NC1CCC(c2ccccc2)CC1 +CCc1nc2cc(NC(=O)Nc3ccc(C#N)cc3)ccc2o1 +CCNC(=O)N(C)Cc1ccccc1N1CCCC1 +CCc1ccsc1C(=O)Nc1cn(CC)ccc1=O +COc1ccccc1CN(C(=O)CNS(C)(=O)=O)C1CC1 +Cn1cc(C(=O)OCCC2CCCO2)c(-c2cccs2)n1 +CC(C)C(=O)NCc1ccc(S(N)(=O)=O)s1 +O=C(Nn1ccc2c(nnc3ccnn32)c1=O)c1ccc(F)cc1 +CC(C#N)(CCc1ccccc1Cl)N1CCOCC1 +CCC(C)c1noc(C2CCCCN2C(=O)Cn2cnnn2)n1 +Cc1cccc(NC(=O)Cn2ncc3ccccc3c2=O)c1C +CN(CC(=O)Nc1ccc(NC2CCCCC2)cc1)S(C)(=O)=O +CC1Cc2ccccc2N1C(=O)c1cc2c(nc1N)CCC2 +CCC1CCCCN1C(=O)Cn1cnc(C(=O)OC)n1 +COCc1cccc(CNC(=O)c2ccc(N)c(C)c2)c1 +COc1cc(OC)cc(C(=O)Nc2ccc3c(c2)OCCCO3)c1 +CC(C)OCc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1 +Cc1ccc(CNC(=O)c2cc(S(N)(=O)=O)c(C)o2)cc1 +CN(CCOCC1CC1)C(=O)Nc1ccc(F)c(C(N)=O)c1 +Cc1ccc(C)c(C(O)CCC(=O)N2CCCCCC2)c1 +CC1CCC2(C)C3(C)CCC2(OC3=O)C12CC(c1ccoc1)OC2=O +CC(C)Oc1ccc(CNS(C)(=O)=O)cc1F +CCCCOC(=O)C(C)N1CC(C)Oc2cccc(N)c21 +CCOCC1CCCN(C(=O)c2csc(Cc3ccccc3)n2)C1 +CC(O)CNC(=O)c1cn(C2CC2)c2cccc(N)c2c1=O +O=C(CN1C(=O)c2ccccc2S1(=O)=O)Nc1ccccn1 +Cc1csc(CN2CCN(C(=O)c3cccs3)CC2)n1 +CN(C(=O)NC1CCC(O)CC1)C1CCCCC1 +Cc1ccc2c(c1)C(N)C(CN1CCOCC1)C(C)(C)O2 +CC(C)(C)C(=O)Nc1cccc(S(=O)(=O)N2CCCCC2)c1 +CN(CC(=O)Nc1ccc(Cl)cc1)c1ncnc2c1cnn2C +NC(=O)CCCNC(=O)c1cc(-c2cccs2)n[nH]1 +Cc1cccc(OCCCCC(=O)N2CCCS2(=O)=O)c1 +O=C(NC1CCN(C(=O)c2ccccc2F)CC1)N1CCC1 +COCCC(C)NC(=O)Nc1cccc(Cl)c1 +O=C(c1ccnc(OCC(F)F)c1)N1CCOc2cccc(F)c21 +Cc1cc(O)n2nc(C3CCCN3C(=O)C(C)(C)C)cc2n1 +COc1cccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +CC(C)CC1CCCCCN1C(=O)c1ccc(-n2ccnc2)nc1 +Nc1cc(N)nc(SCCOc2cccc(Cl)c2)n1 +COc1nc(C(=O)NCc2c(C)cc(C)[nH]c2=O)cc2ccccc12 +CC(NS(N)(=O)=O)c1ccc(-n2ccnc2)cc1 +CN(CCC#N)C(=O)c1ccccc1OCc1ccc(F)cc1 +O=C(C1CCC1)N1CCC(c2nc(-c3ccsc3)cc(=O)[nH]2)CC1 +CC=CCOC(=O)c1ccc(Cn2cccn2)cc1 +CC(NC(=O)c1csc(-c2nc[nH]n2)n1)c1cc2ccccc2o1 +O=C(NCc1nncn1C1CC1)C1(c2ccc(F)cc2)CCCC1 +CC(=O)N(C)c1ccc(NC(=O)N(C2CC2)C(C)c2ccco2)cc1 +COc1ccccc1N1CCC(CNC(=O)NCc2ccccc2)C1 +Cc1ccoc1C(=O)OC(C)c1nc(C(C)(C)C)no1 +NC(=O)c1cccc(CNC(=O)C2COc3ccc(F)cc3C2)c1 +CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)c(N)c1 +COC(=O)c1cc(S(=O)(=O)NCc2ccc(OC)cc2)cn1C +Cc1nn(CCO)c(C)c1CNCC(O)c1ccc(F)cc1F +C=CCNC(=O)C(C)Nc1ccc(Cl)c(C(N)=O)c1 +CCOC(=O)c1oc2ccccc2c1CN1CCNC(=O)C1 +Cc1ccc(C)c(NS(=O)(=O)c2ccc(S(C)(=O)=O)cc2)c1 +Cc1cc(O)c(C(=O)Nc2ccccc2)c(=O)n1Cc1ccco1 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)N(C(C)C)C1CCC1 +CCOC(=O)N1CCC(OC(=O)CCc2ccccc2F)CC1 +CC(=O)Nc1ccc(NC(=O)C2CCCO2)cc1Cl +COc1c(C)cnc(CNC(=O)c2ccccc2-n2cccn2)c1C +Nc1ncc(C(=O)NC2CCCCNC2=O)c(-c2ccccc2)n1 +Clc1cccc(CN2CCN(Cc3nc(C4CC4)no3)CC2)c1 +O=C(COC(=O)Cc1c[nH]c2ccccc12)Nc1c(F)cccc1F +Cc1c(F)cccc1S(=O)(=O)NC(C)c1nnc2ccccn12 +CC(C)NS(=O)(=O)C1CCOCC1Cc1ccccc1F +CCOc1cccc(C(C#N)N(C)S(C)(=O)=O)c1 +Cc1cc(C(=O)OC(C)C(=O)Nc2ccccc2Cl)c(C)o1 +COC(=O)c1ccc(C(=O)Nc2ccc(-c3c[nH]cn3)cc2)cc1 +CC(C)CCN(CC1CCCO1)S(=O)(=O)c1ccc(C#N)cc1 +Cc1ccccc1-c1nnc(SCC(=O)NC(C)(C#N)C(C)C)o1 +Cc1ccc(-c2nnc(C(C)N3CC4OCCN(C)C4C3)o2)cc1 +CCC(CNC(=O)c1n[nH]c(=O)[nH]1)c1ccccc1 +N#CC1(C2C=CC=CC2)CC2=CC(N)C=CC2(F)C1 +Cc1cc(C)c(NC(=O)NCCCOC2CCCC2)c(C)c1 +CC(=O)NC(C(=O)OCC(=O)Nc1cccc(C)c1)C1CCCC1 +NC(=O)c1ccc(OCC(=O)Nc2nccs2)cc1 +COCC(NC(=O)Cn1cnc2ccccc2c1=O)c1ccnn1C +Cc1nc(C(=O)Nc2ccc(Oc3ccccc3)cc2)co1 +Fc1cc(CNc2ncnc3[nH]ncc23)ccc1-n1ccnc1 +O=C(CCc1ccc2[nH]ccc2c1)NC1CCCC1 +COCCOC1CCN(Cc2cnc(-c3ccsc3)s2)CC1 +Cc1cc(C)n(CCCNc2nc(C3CC3)nc3c(C)nn(C)c23)n1 +COc1ccc(OCCN2CCNc3ccccc32)cc1 +Cc1nc(C)c2c(C)c(C(=O)OC(C)C3CC3)sc2n1 +O=C(Nc1ccccc1OC(F)F)OCC(F)(F)F +COCCC(C)NC(=O)C(C)Oc1ccccc1Br +Cc1ccc(S(=O)(=O)NCCNC(=O)c2cccc(C)c2O)cc1 +CCOC(=O)C(Cc1ccccc1)NC(=O)c1ccc(F)cc1 +CC(=O)Oc1c(Cc2ccccc2)c(=O)oc2ccccc12 +CC(C)(C)c1ncc(C2NC(N)=Nc3nc4ccccc4n32)s1 +COc1ccc(CN(C(=O)C(C)C)c2ccncc2)cc1 +CCCCN1CNc2c(c(=O)[nH]c(=O)n2-c2cccc(C)c2C)C1 +Cc1ccc(CNc2cc(C)nn3cnnc23)cc1 +COC(=O)CNC(=O)c1c(-c2c(F)cccc2Cl)noc1C +CCCOc1ccc2c(c1)C(c1cc[nH]c1)NCC2 +COCC(=O)n1nc(-c2ccco2)nc1NCc1cccs1 +NC(=O)c1ccc(OCC(=O)c2cnc(N3CCCCC3)s2)cc1 +CCc1noc(CC)c1CNC(=O)c1cc(Cl)c2c(c1)OCO2 +COc1ccccc1C(C)NC(=O)COc1cccc2c1CCC2=O +O=C(NCc1ccnc(OCC2CC2)c1)c1ccc2c(c1)OCCO2 +Cc1ccc(NC(=O)CNC(=O)c2ccc3c(c2)OCO3)c(O)c1 +O=C1c2ccccc2NC(c2csc(C3CC3)n2)N1C1CC1 +CCOC(=O)c1[nH]c2ccc(Br)cc2c1N +COc1ccc(N2C(=O)CN(C(=O)c3nc(C)c[nH]3)CC2(C)C)cc1 +Cc1nc(SCC(=O)N(CCC#N)c2cccc(Cl)c2)oc1C +CCOC(=O)C1CCN(C(=O)c2c(O)cnc3ccccc23)CC1 +CC(=O)c1cccc(NC(=O)c2ccc(OCC3CCCO3)cc2)c1 +CC(C)N(C)C(=O)C1CCN(S(=O)(=O)c2cccnc2)CC1 +CN(C)C(=O)c1ccc(C(=O)Nc2ccc(C(N)=O)c(F)c2)cc1 +CCN(C)C(=O)c1ccccc1N1CCC(NC(=O)COC)CC1 +C=CCNC(=O)COC(c1ccccc1)c1ccccc1 +FC(F)(F)c1cnc(N2CCOC(Cn3cccn3)C2)c(Cl)c1 +O=C(Cc1noc2ccccc12)N1CCN(c2nccs2)CC1 +N#Cc1c(CN2CCN(S(N)(=O)=O)CC2)cn2ccccc12 +COC(=O)c1cc(COc2ccccc2F)oc1C +CCNC(=O)CN1CCN(C(=O)N2CCCCC2)CC1 +Cc1noc(CNc2ccc(-c3ccccc3)cc2)n1 +COC(=O)CNC(=O)CSc1nccn1-c1cc(C)cc(C)c1 +Cc1ncc(CNc2ccc(N3CCCC3=O)cc2)s1 +O=C(NCc1ccco1)NCC1CCN(c2ccccc2)C1 +CC1CCC(NC(=O)C(C)Sc2nnc(C3CC3)n2C)CC1 +COc1ccc(C(=O)Nc2ccc(C)c(O)c2)cc1 +COc1ccc(C(=O)CCCC(=O)Nc2nc(C)no2)cc1 +Cc1noc(-c2cccc(NC(=O)c3ccccc3F)c2)n1 +COc1ccc(-n2nc(N)c(=O)cc2C)c(OC)c1 +CC(=O)Nc1ccsc1C(=O)N1CCC(n2nc(C)cc2C)C1 +COC(=O)C12CC3CC(CC(C(=O)OC)(C1)C3=O)C2=O +COc1cc(C(C)NC(=O)c2ccc(F)nc2)cc(OC)c1OC +NC(=O)c1n[nH]c2ccc(NC(=O)c3ccc4ccccc4c3)cc12 +CC(C)C(NC(N)=O)C(=O)Nc1ccc2c(c1)oc(=O)n2C +CCOC(=O)C1CN(C(=O)c2ccco2)CCN1C(=O)c1ccco1 +COc1ccc(Br)c(C(=O)NCC2CCCO2)c1 +Nc1ccccc1OCc1nnc(C2CCCC2)o1 +COC(=O)c1sc(NC(=O)CCSc2ccccc2)nc1C +CC(Cc1cccc(Cl)c1)NC(=O)c1cccc(C(N)=O)c1 +Nc1ccc2oc(CC(=O)NCc3ccncc3)nc2c1 +O=C(N(Cc1ccsc1)C1CC1)C1(c2cccs2)CC1 +c1ccc(-n2cc(CNc3ccccc3-n3cccn3)cn2)cc1 +O=C(N=c1[nH]c2ccccc2[nH]1)c1ccc(-n2ccnc2)nn1 +CN(C)c1cccc(C(=O)N2CCC(Oc3cccnc3)CC2)c1 +CCOc1ccc(C(=O)CCC(=O)Nc2ccc(F)c(F)c2)cc1 +CC1CCCN(C(=O)c2cc3cnn(C(C)C)c3nc2N)C1 +CCC(CC)C(=O)N1CCC(NC(=O)c2ccc3[nH]cnc3c2)CC1 +O=C(CCC(=O)c1ccccc1)NCc1cccnc1 +COc1ccc(NC(=O)Nc2ccc(CCO)cc2)c(OC)c1 +CCOc1ccc(CNC(=O)c2cc(-c3ccc(F)cc3)[nH]n2)cc1 +CN(C)C(=O)CN(C)C(=O)c1cc(C2CC2)nn1-c1ccccc1 +Cc1nn(C)c(C)c1NC(=O)C1(C)Oc2ccccc2N=C1O +CCc1ccc(CCC(=O)NCc2nncn2CC)cc1 +Cc1ccccc1-c1noc(-c2sc3nc[nH]c(=O)c3c2C)n1 +CCOc1ccccc1CC(O)C(=O)N1CCNCC1 +CCCc1nc(CN2CCN(C(=O)CCC(C)C)CC2)cs1 +Cc1cc(NC(=O)c2cccc3c2ccn3C(C)C)nn1C +O=C1OC(C(=O)Nc2nc3c(s2)CCCC3)Cc2ccccc21 +O=C(Nc1ccc(OC2=NS(=O)(=O)c3ccccc32)cc1)C1CC1 +CCCc1cc(C(=O)N2CCC(C(O)c3cccs3)CC2)no1 +CCN1c2ccccc2C2CN(S(C)(=O)=O)CCC21 +Cc1nc(-c2cccs2)ccc1C(=O)NC(C)C(N)=O +CCS(=O)(=O)NCc1cccc(COc2ccccc2)c1 +Cc1[nH]ncc1CCCNC(=O)N1CCN(CC2CCCO2)CC1 +CCC(C)(C)C1CCC(=O)C(C2(O)C(=O)Nc3ccccc32)C1 +O=C(CN1CCCS1(=O)=O)N1CCCC1c1ccccc1Cl +O=C(CCCC(=O)Nc1ccccc1O)Nc1ccccc1O +CN(CCC(F)(F)F)C(=O)NCc1nc2ccccc2s1 +CC(=O)NC1CCN(c2ccc(C#N)cc2C(F)(F)F)CC1 +CCS(=O)(=O)c1ccc(O)c(NC(=O)C(C)n2nccc2C)c1 +CN1C(=O)Cc2cc(S(=O)(=O)N3CCCCC3)ccc21 +CCCC(=O)N1CCCC1C(=O)OCC1CC(=O)N(C2CC2)C1 +Cc1ccc(S(=O)(=O)N(CCO)C2CCCC2)c(C)c1 +CCn1c(C)nnc1CNC(c1ncccc1C)C(C)C +C#CCNC(=O)C1CCN(C(=O)N(CC)CC)CC1 +O=C(Cn1cnc2ccsc2c1=O)NC1CCCCCC1 +CN(Cc1ccccc1)c1nc(C#N)cc(C2CC2)n1 +Cc1c(OCC(=O)NCc2ccccc2Cl)c(=O)ccn1C +Cc1ccc(C(=O)Nc2ccc(Br)cc2N)s1 +Cc1ccc(Br)cc1S(=O)(=O)NCC(C)C +Nc1cc(-c2n[nH]c(-c3ccncc3)n2)ccc1O +COC(=O)C(C)NC(=O)C1(c2ccc(Br)cc2)CC1 +Cn1cc(C2COC3(CCN(C(=O)c4ccccc4)CC3)C2)cn1 +CC(C)c1cc(C(=O)Nc2ccc(F)cc2)nc2ccnn12 +Cc1ccc(OCC(=O)NCCCn2ncccc2=O)cc1 +O=C(CCc1ncc(-c2ccccc2)o1)N1CCc2ccccc21 +Cn1cc(Br)c(C(=O)NCC2CCCO2)n1 +COCCOc1ncccc1NC(=O)c1scnc1C1CC1 +CCn1nc(C)c(CNC(=O)CCC2CCCC2)c1C +CC(C)Oc1ccc2c(C(=O)NCC(=O)N(C)C)cc(=O)oc2c1 +COCCN(Cc1cccs1)C(=O)c1cc(C)c(C)s1 +COC(=O)c1ccc(NC(=O)c2cncn2-c2ccccc2)cc1 +CCn1cnnc1CNC(=O)N1CCOCC1CC(C)C +CC(=O)c1ccc(OCC(=O)Nc2nccs2)c(N)c1 +CCCNC(=O)c1nn(CC)cc1NC(=O)c1c(F)cccc1F +CN1CCN(C(=O)Cc2ccccc2Cl)CC1 +COc1ccccc1NC(=O)CSc1ccc(C(C)=O)cc1 +CC(=O)Nc1ccc(NC(=O)c2ccc(OCC(C)C)cc2)cc1 +CC(=O)c1nc(-c2ccc(Br)cc2)ns1 +COc1cc(OC)c(NS(=O)(=O)c2cc(C)ccc2F)cc1F +Cc1ccc(NC(=O)NCCC(=O)N(C)C)c(C)c1 +CCOC(=O)NCCC(=O)Nc1cnc(-c2ccccc2)nc1 +CC(c1ccccc1)N(C)C(=O)CCNC(=O)Nc1ccccc1 +NC(=O)C1(NC(=O)c2cc(-c3ccc(Cl)cc3)n[nH]2)CCCCC1 +O=C(Cc1csc(NC(=O)c2cnccn2)n1)Nc1ccccc1 +O=C(Nc1cc(Cl)ccc1-n1cncn1)c1cc2ccccc2o1 +CC(c1ccc(F)cc1)N(C)C(=O)c1ccc(-n2ccnn2)cc1 +N#Cc1ccc(C(=O)N2CCC3(CCc4ccccc4O3)CC2)cc1 +CCOc1ccc(C(O)(CCN2CCOCC2)c2ccccc2)cc1 +CC(Sc1ncn[nH]1)C(=O)Nc1ccc(OC(F)(F)F)cc1 +Cc1csc(=O)n1CCC(=O)OCc1cccc(C#N)c1 +CCCOC1CCCN(C(=O)c2cnc3c(c2)c(C)nn3C)C1 +Cc1nn(C)c(C)c1NC(=O)c1cccc(F)c1F +Cc1ccc(-n2nnnc2NCCNc2ncccc2C#N)cc1 +CC(NC(=O)NCCCn1cccn1)C(C)(C)c1ccccc1 +COc1ccc(CNC(=O)Nc2c(F)cccc2F)cc1 +CCOc1ccccc1NC(=O)c1ccc(NC(=O)CC)cc1 +COC(=O)C1CCCN(C(=O)c2scnc2C2CC2)C1 +COc1ccc(OC)c(NC(=O)NCCN2CCOCC2)c1 +CC(NC(=O)NCc1cccnc1)c1cccc(N2CCCC2=O)c1 +CCOC(=O)c1c(C2CC2)csc1NC(=O)Cc1cccc(F)c1 +O=C(COC(=O)COc1ccc(Cl)cc1)NC1CC1 +O=C(NC1CCCCC1)c1ccn(C2CCCC2)n1 +CC(C)C(=O)Nc1nc2cc(NS(C)(=O)=O)ccc2s1 +COc1cccc2c1OCC(C(=O)NCc1cnc(SC)n1C)C2 +CC(C)CNC(=O)C1CC(=O)OC12CCCCC2 +CC(C)c1ncncc1C(=O)N1CCN(Cc2cccnc2)CC1 +CCC(=O)N(Cc1cc(=O)[nH]c2ccccc12)c1ccc(OC)cc1 +Cc1nc(-c2ccc(CNC(=O)c3ccccc3F)o2)cs1 +COc1cccc(C2CN(Cc3cc(F)cc(F)c3)CCO2)c1 +O=C(NC1CC1)c1ccc(-c2ccc(Cl)cc2)[nH]c1=O +O=C(COCc1nc2ccccc2s1)NCC1CCOC1 +CC(C)n1c(=O)c2c(ncn2C(C)C)n(-c2ccc(F)c(F)c2)c1=O +CCc1ncsc1C(=O)NCc1cccc(-c2n[nH]c(C)n2)c1 +O=C(Nc1cc(N2CCOC2=O)ccc1F)C1CCc2ccccc21 +O=C(CCc1ccccc1F)NCCOc1cccnc1 +O=C(c1cccs1)N1CCN(CC(O)CN2CCOCC2)CC1 +CCOc1ccc(CC(=O)NCc2cn(-c3ccccc3)nn2)cc1 +CCn1cc(Br)c(C(=O)NC(C)c2ccccc2)n1 +CCc1cc(N)n(-c2ncc(Cl)cc2Cl)n1 +N#Cc1c(-c2cccn2-c2ccccn2)cc(-c2ccco2)nc1N +CCN(Cc1c[nH]nc1-c1ccc(F)cc1)CC(C)C#N +Cc1ccc(N2CCCN(C(=O)CCc3c(C)noc3C)CC2)nn1 +Cc1nn(C)c(C)c1NC(=O)COC(=O)c1cccc2c1OCCO2 +CCC(NC(=O)c1ccccc1F)c1ccc(Cl)cc1 +Nc1ccccc1S(=O)(=O)NCc1ccc(Cl)cc1 +Cn1c(=O)cc(NCc2cccnc2)n(Cc2ccccc2)c1=O +Cc1nc(C)c(-c2nnc(SCc3ccc(F)c(F)c3)o2)s1 +COC(=O)c1c(NC(=O)c2ccoc2C)sc2c1CCC(C)C2 +COc1ccc(-c2nc3ccccc3o2)c(OC)c1OC +CCOc1ccc(C(O)Cc2ccccc2OC)cc1 +COc1ccc(O)c2c1C(c1cccc(F)c1F)NCC2 +CC(NC(=O)Nc1cccc(F)c1F)c1ccc(-n2ccnc2)cc1 +CC(O)C1OC(n2c(=O)cc[nH]c2=O)C(O)C1O +CC(CC(=O)NCc1csc(=O)[nH]1)c1ccc(F)cc1F +COc1ccc(F)cc1NC(=O)c1cc(C(C)C)[nH]n1 +COCCN(CC(C)C)S(=O)(=O)N1CCCC(C)C1 +Cc1nonc1CC(=O)NC(C)Cn1c(=O)oc2ccccc21 +CN(C)S(=O)(=O)c1ccc2c(c1)N(C(=O)C1CCCO1)CCC2 +Cc1ncc(CNC(=O)c2ccc(Cn3ccccc3=O)o2)s1 +CC(=O)c1cccc(NCC(=O)Nc2cc(C)nn2C)c1 +CCCCN(CC)C(=O)c1c(OC)cccc1OC +COc1ncccc1NC(=O)c1cc(F)ccc1F +Cc1noc(C)c1S(=O)(=O)NCCc1nc(N)nc(N(C)C)n1 +O=C1NCC(=O)N2CCN(C(=O)Cn3cnc4ccccc43)CC12 +CC(NC(=O)Nc1ccc(F)cc1C#N)c1ccc(C#N)cc1 +C=CCn1c(SCC(=O)NCCC)nc2ccccc2c1=O +CC(C)Oc1ccc(C(=O)NCC2CCCO2)cc1Br +O=C(Nc1ccc2cc[nH]c2c1)c1ccc2nnnn2c1 +NC(=O)C1(CNC(=O)c2cc(F)ccc2F)CCOCC1 +C=CCN(Cc1cnn(-c2ccc(F)cc2)c1)CC(F)(F)F +CCCn1c(C)nnc1SCC(=O)c1cc(C)ccc1C +NS(=O)(=O)c1ccc2nc(NC(=O)c3cnccn3)sc2c1 +O=C(CS(=O)(=O)c1ccccc1)Nc1nnc(-c2ccncc2)o1 +CC(Cc1cccc(F)c1)C(=O)Nc1cccnc1 +CCCN(C)C(=O)CCc1nc2ccccc2c(=O)[nH]1 +Cc1onc(-c2c(F)cccc2Cl)c1C(=O)NC(C)(C)C +c1cnc(NC2COC3(CCN(Cc4nccs4)CC3)C2)cn1 +COc1ccc(CCC(=O)Nc2ncn(Cc3ccccc3)n2)cc1 +CCCCSc1ccccc1C(=O)N1CCOCC1 +Cc1occc1-c1nnc(SCc2cc(-c3ccco3)on2)n1C +CC(C)(C)C(=O)NCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +COC(=O)C(C)(C)NCc1nc(-c2cccs2)oc1C +CCOC(=O)N1CCN(C(=O)c2ccc3ccccc3c2O)CC1 +C#CCSc1cccc(C(=O)NC2(C#N)CCOCC2)c1 +Cc1cc(C(=O)Nc2cccc(COCC(F)(F)C(F)F)c2)no1 +COCC(=O)NCC#Cc1ccc(NC(C)=O)cc1 +CCOc1ccc(C(F)(F)F)cc1NC(=O)c1ccco1 +CCOc1ccc(C(C)NC(=O)C2CCOC2)cc1 +O=C(NC1CCc2[nH]ncc2C1)NC(c1ccc(F)cc1)C1CCC1 +Cc1ccsc1C(=O)NCCC(=O)NCc1cccnc1 +CC(C)(C)C(O)CCNC(=O)c1ccc(F)cc1F +COc1cccc(CNC(=O)c2cc(CC(C)C)no2)c1OC +CN(C(=O)c1cc(=O)c2ccccc2o1)C1(C#N)CCC1 +CS(=O)(=O)NCC1CCN(S(=O)(=O)c2ccccc2)CC1 +COc1ccc(-c2c(-c3cccnc3)noc2N)cc1 +CC(Cc1ccc(O)cc1)NC(=O)NC1CCCCC1 +O=C(Cc1ccc[nH]1)Nc1nnc(Cc2ccc(F)cc2)s1 +CCc1cccc(NC(=O)Cn2c(=O)oc3ccccc32)c1 +CN(CCC#N)S(=O)(=O)NCC(=O)Nc1ccc(Cl)cc1 +CC1(NC(=O)Cc2csc(-c3ccccn3)n2)Cc2ccccc2C1 +CC(=O)N(Cc1ccco1)C1CCN(c2nc(C)cc(C)n2)CC1 +Cc1ccc(-n2cnc3ccccc3c2=O)cc1N +Cc1ccc(N(CC(=O)NC(C)C)S(C)(=O)=O)cc1 +Cn1ccnc1SCC(=O)c1cc2c(cc1F)NC(=O)CC2 +Cc1nnc(CN(C)Cc2ccccc2N2CC(C)OC(C)C2)n1C +O=C(NCc1nnnn1-c1ccccc1)c1cccc2ccccc12 +Cc1cccc(NC(=O)CNc2nnnn2-c2ccccc2)c1C +Cc1cc(C)nc(SCC(=O)Nc2ccccc2CC(N)=O)n1 +CC(=O)c1cccc(NC(=O)Nc2cc(C)nn2Cc2ccccc2)c1 +CC(N(C)C(=O)CNC(=O)c1ccsc1)C(C)(C)C +Cc1ccc(CNC(=O)c2csc(C(N)=O)n2)o1 +CC(C)CC(=O)Nc1ncn(Cc2ccccn2)n1 +CCc1ccc(OCC(=O)NC2CCN(C(N)=O)C2)cc1 +COc1cccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)c1 +CC(C)CC(=O)Nc1nc(C(=O)NCc2cccc(F)c2)cs1 +CC(C)NC(=O)c1c(-c2ccccc2)nc2sccn2c1=O +N#Cc1cccc(Cn2ccnc2Cc2cccs2)c1 +Cn1cc(CNc2ccc(F)cc2Br)cn1 +CCC(=O)Nc1ccc(C)c(NC(=O)NCC(=O)N(C)C)c1 +COc1ccc(-c2ccc(CCC(=O)Nc3ccn(C)n3)o2)cc1 +CC(=O)Nc1cc(NC(=O)C(C)Sc2nncn2C)ccc1F +CCOC(=O)c1cnc(-c2ccncc2)nc1C(F)(F)F +Oc1cc(O)c2c(c1)C(c1cc(F)c(F)cc1F)NCC2 +CC1CN(C(=O)c2cc(=O)c3ccccc3[nH]2)CCO1 +CCCn1ncc(-c2ccc(C)c(C)c2OC)c(C#N)c1=O +CCOC(=O)c1c(N)c(C(N)=O)nn1-c1cc(C)ccc1C +COCCNC(=O)Cn1nc(-c2cccs2)c2ccccc2c1=O +Cc1cc(Oc2ncccc2C#N)ccc1NC(=O)CCn1cncn1 +O=c1ccc(S(=O)(=O)N2CCN(C3CC3)CC2)c[nH]1 +CC(Cc1ccco1)NS(=O)(=O)c1ccc2c(c1)CCCC(=O)N2 +CCOc1ccc(OC)cc1NC(=O)NCc1cnn(C)c1C +CCN(Cc1ccc(C)o1)C(=O)CCCc1cn[nH]c1 +Cc1cc(C(F)(F)F)nn1CC(C)C(=O)N1CCCC1 +N#Cc1cccnc1N1CCN(C(=O)NCCN2CCOCC2)CC1 +CCC(C)n1nccc1NC(=O)Cn1c(C)csc1=O +Cc1ccc(OCC(=O)NCCc2ccccc2)cc1 +Cc1cc(CSc2nnc(-c3ccccc3C)n2C)no1 +CC(C)CNC(=O)CN1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +O=C(c1ccoc1)N1CCCC1c1nc(-c2ccccn2)no1 +CC(=O)N(Cc1cc2ccc(C)cc2[nH]c1=O)c1cc(C)ccc1C +O=C(Oc1ccc(F)cc1)C1CCCN1C(=O)c1cccs1 +COc1ccccc1C1CCCN1C(=O)Cc1ccc[nH]1 +Cc1cc(=O)c(C(=O)N2CCOc3ccccc32)nn1-c1ccccc1 +O=C(c1ccc(C(F)(F)F)cc1)N1CCc2ccccc2C1 +Cc1csc(CNC(=O)Nc2ccc(OC(F)F)c(F)c2)n1 +CN(Cc1cc(=O)n2nccc2[nH]1)CC1CCCC1 +CC(C)(C)CC(=O)Nc1ccccc1C#CCCO +O=C(COc1ccc(F)cc1Cl)Nc1ccc(O)cc1 +CCCc1nn(-c2nc3ccccc3[nH]2)c(O)c1CCC#N +Cc1cc(Cl)ccc1OCCCNC(=O)N1CCC(C(N)=O)C1 +CC(C)c1cccc(C(C)C)c1NC(=O)Cn1cnnn1 +Cc1ccc(CNC(=O)c2ccc(=O)n(C)c2)s1 +Cc1ccc2oc(C(=O)N3CCC(OCC(C)C)CC3)cc2n1 +Cc1nc(C2CCCN2Cc2nc(Cc3ccccc3)no2)no1 +Cc1ncc(CN(C)Cc2nc(-c3ccc4c(c3)OCO4)no2)s1 +CC(C)(C)n1cc(C#N)c(NC(=O)c2cccc(-c3ccoc3)c2)n1 +CCc1ccc(OCC(=O)NCCc2csc(C)n2)cc1 +Cc1cn2nc(NC3CCCCC3C)sc2n1 +CCN(CCO)C(=O)C(C)Oc1ccc(Br)cc1 +CC1c2ccccc2OC1C(=O)Nc1c[nH]cc(Br)c1=O +COc1cc(C)ccc1OC(=O)c1csc(NC(C)=O)n1 +Cc1c(C(=O)NCC(C)O)cnn1-c1ccc(Br)cc1 +CN(C)c1ccc(C(=O)N=c2sccn2C)cc1 +CSc1cccc(NC(=O)C2CC3C=CC2C3)c1 +Cc1sc(=O)n(CC(=O)Nc2nc(-c3ccccc3)cs2)c1C +CC(=O)c1c(C)oc(N)c1C(=O)c1cccc(F)c1 +O=C(NCC1Cc2ccccc2O1)Nc1nccs1 +CCOCCn1c(C)cc(C(=O)n2ccnc2)c1C +COc1ccc(C(=O)N(CC(C)C)C(C)C)cc1N +COc1ccnc(NC(=O)c2cc(C(C)C)[nH]n2)c1 +Cc1cc(NC(=O)c2noc3c2CCc2ccccc2-3)no1 +CCN(CC(=O)NCc1ccc(F)cc1)C(=O)C1CCC1 +Cn1ccnc(NC(=O)Cn2c(=O)[nH]c3ccccc3c2=O)c1=O +Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +CCOc1cc(NC(=O)c2ccc(C#N)cc2)ccc1OC +CC(=O)Nc1cccc(NS(=O)(=O)c2ccc(C)cc2C)c1 +c1ccc2c(c1)nnn2C1(N2CCOCC2)C2CCCC21 +Cc1ccc(NC(=O)COc2ccccc2CO)c(C)c1 +Cc1ccc(OCc2nnc(-c3cnc4onc(C)c4c3)o2)cc1C +CS(=O)(=O)c1cnc(N2CCC(O)C2)nc1N +COc1cccc(CNC(=O)COC(=O)c2cccc(Cl)c2)c1 +CC(C(=O)Nc1sc2c(c1C(N)=O)CCCC2)c1ccsc1 +CC(=O)Nc1ccc(NC(=O)CN2CCCc3ccccc32)cc1 +CCC(NC(=O)N1CCc2c(nc(N)[nH]c2=O)C1)c1ccccc1 +Cc1ncc(CN(C)C(=O)CNC(=O)OC(C)(C)C)s1 +O=C(Nc1cccc(OC(F)F)c1)c1ccoc1 +CC(C)c1noc(CCC(=O)Oc2ccc(C(F)(F)F)cc2)n1 +COc1c(Cl)cccc1NC(=O)NCCN1CCOCC1 +CC1CCCC(C)N1C(=O)CSc1ccccc1 +O=C1CN(C(=O)CCCc2nc(-c3ccccc3)no2)CCN1 +O=C(NCC(O)c1ccco1)c1ccn(-c2ccc(F)cc2)n1 +Cc1noc(C2CCN(c3ncnc4c3cnn4CCC#N)CC2)n1 +COc1ccc(C)cc1-c1[nH]c(C2CC2)nc1C#N +COc1ccc(Cc2nccn2C(C)C(N)=O)cc1OC +COC(=O)CNC(=O)c1cc2ccccc2cc1OC(F)F +Cc1cccc(OCCCn2nnc(C#N)c2-c2ccco2)c1 +O=C1CSc2ccc(C(O)C(=O)NC3CC3)cc2N1 +CC(=O)Nc1ccc(S(=O)(=O)NC(N)=O)cc1 +CCCC(C)NC(=O)C1CCCN(S(=O)(=O)c2cnn(C)c2)C1 +COCCCn1c(-c2cccc(OC)c2)ccc(C#N)c1=O +N#Cc1cc(CNc2ncccc2Cl)ccc1F +COC(=O)c1sc2nc(C)nc(NCc3cccnc3)c2c1C +C#CC(C)OC(=O)c1cncnc1-c1ccccc1 +Cc1cc(NC(=O)Nc2ccc(Cl)cc2Cl)no1 +COc1ccc(NC(=O)C2CCN(C(C)=O)CC2)cc1C +O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc1ccccc1F +COC(=O)CCNC(=O)c1ccc(-n2ccc(C(F)(F)F)n2)cc1 +Cc1cccc2c(CCNC(=O)NC(C)CCCO)c[nH]c12 +CCOc1ccccc1CNC(=O)CN(C)S(C)(=O)=O +CN(C)C(=O)CNC(=O)c1cc2ccccc2cc1NC(=O)C1CC1 +COc1cc(CNc2cc(C)on2)ccc1Cl +N#Cc1cccc(OCCn2ncc(Cl)c(Cl)c2=O)c1 +CCOC(=O)C1CCN(c2nnc(N3CCCC3=O)s2)CC1 +CCn1nc(C)cc1C(=O)N(C)c1ccc(C)c(Cl)c1 +COC(=O)c1noc(C(=O)N2c3ccccc3CC2C)c1N +O=C(COC(=O)C1CCC1)Nc1ccc(F)c(Cl)c1 +CC(C)(C)c1nnc(NC(=O)NCc2ccccn2)s1 +CCOc1ccccc1NC(=O)NCC(=O)OC(C)C +Cn1cc(C(=O)Nc2ccc(Cl)cc2)c(=O)c2cc(Cl)ccc21 +COCCC(=O)Nc1cnc(-c2ccc(C(F)(F)F)cc2)nc1 +Cn1cccc1C(=O)OCc1ccc(-n2cccn2)cc1 +N#Cc1cccc(NC(=O)Nc2ccc(Oc3ccncc3)cc2)c1 +O=c1[nH]c2cc3c(cc2cc1CNc1ccc2[nH]ncc2c1)OCCO3 +CC(C)NS(=O)(=O)c1cccc(Cl)c1C#N +COc1cc(C(C)=O)ccc1COc1ccc(C(N)=O)cc1OC +CCc1c(C)sc(NC(=O)c2c(C)c(C)nn(C)c2=O)c1C#N +COc1ccc(-c2ccc(CC#N)c(=O)n2C2CC2)cc1 +Cc1ccc(F)c(S(=O)(=O)N(C)Cc2ccsc2)c1 +CC(=O)N1CCN(CC(O)c2ccc(N)cc2)CC1 +CCc1ccc(CNC(=O)Cn2nnnc2CC)s1 +O=C(Cc1csc(Nc2ncccn2)n1)NC1CCCCC1 +COc1ccc(-c2c(CCO)sc3nccn23)cc1 +Nc1nccnc1C(=O)NCc1ccc(CN2CCOCC2)cc1 +Cc1cc(C)c(NC(=O)CN(C)C(=O)c2cc(Cl)c[nH]2)c(C)c1 +CCC1(C)Cc2c(sc3c2c(=O)n(C)c2nncn32)CO1 +COCCCCCNC(=O)Nc1ccc2c(c1)COC2 +FC(F)(F)c1n[nH]c2c1CN(CCc1ccccn1)CC2 +Cc1ccccc1-n1cnnc1SCc1ccc(C(N)=O)cc1 +CCOCC1CCCN(C(=O)NCc2cccnc2OC)C1 +CCOc1ccc(NC(=O)NCCCn2ncccc2=O)cc1 +O=C(OCc1ccc(-n2cccn2)cc1)c1cc(=O)[nH]c2ccccc12 +CC(NC(=O)CNC(=O)c1c[nH]c2ccccc2c1=O)c1ccccc1 +CCC(C)NC(=O)c1ccc(NC(=O)c2ccnc(C3CC3)n2)cc1 +Cn1ccnc1SCC(O)c1ccc(C(F)(F)F)cc1 +CCN(CC)c1ccc(C(=O)Nc2ccc3nc[nH]c(=O)c3c2)cn1 +CC(C)CNC(=O)COc1ccc(C(=O)C(C)C)cc1N +Cc1cc(Cl)ccc1OC(C)C(=O)Nc1c[nH]c(=O)[nH]c1=O +CC(=O)Nc1cccc(C(=O)OCC(=O)Nc2ccccc2)c1 +CCn1nc(-n2cnnc2)c(NC(=O)c2cccc(OC)c2)c1C +CCn1nc(C)c(CNS(=O)(=O)c2ccc(OC)cc2)c1C +O=C(NCC#Cc1ccccc1)Nc1ccccc1F +O=C(CCNC(=O)c1ccc(Cl)cc1)NCc1ccccc1F +CCc1noc(CC)c1CNS(=O)(=O)N1CC(C)OC(C)C1 +OC(CC(Cl)(Cl)Cl)c1nc2ccccc2s1 +COc1cc2c(cc1OC)CN(C(=O)CCc1ccccc1O)CC2 +O=C(c1csnn1)N1CCCC1c1noc(C2CC2)n1 +COc1ccccc1C(O)CCNc1ccc(C#N)cc1 +CC(C)(C)c1nc(CNS(=O)(=O)CC2CCOCC2)no1 +Cc1cc(=O)[nH]c(-c2ccc(NC(=O)c3cn4cccnc4n3)cc2)n1 +Cc1ccc2c(n1)OCCN2C(=O)c1cc(C)n(C2CC2)c1C +O=C(NCc1cccs1)NCC1COC2(CCCC2)O1 +COC(=O)c1ccc(Nc2ncnc(-n3ccnc3)c2N)cc1 +O=C1CCCCN1Cc1ccc(C(=O)N2CCN(CCO)CC2)cc1 +COc1ccc(OC)c(CC(=O)NCc2ccnc(OC)c2)c1 +COCc1ccc(CNC(=O)c2cccc(OC)c2OC)cc1 +N#Cc1cc(-c2ccc3c(c2)OCCO3)n(CCCO)n1 +Cc1nncn1-c1ccc(C(=O)Nc2ccc(F)cc2)cc1 +CC(C)(CNC(=O)c1ccccc1C(F)(F)F)c1ccncc1 +COC(=O)CSc1nc2[nH]ncc2c(=O)n1-c1ccccc1 +CC(=O)N1CCC(C(=O)Nc2ccc3c(C)cc(=O)[nH]c3c2)CC1 +Cc1ccc2c(CC(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)coc2c1C +Cc1ccc(NC(=O)Nc2ccc(-n3ccnc3C)nc2)cc1 +CC(=O)Nc1ccc(NC(=O)c2ccco2)c(C)c1 +COc1ccc(NS(=O)(=O)c2cc(C)sc2C)cc1Cl +CC(C)Cn1c(SC2CC(C)OC2=O)nnc1-c1ccco1 +COCc1[nH]nc(C)c1-c1cc(OC)cc(OC)c1 +CC(C)CNC(=O)Nc1nnc(CC(C)C)s1 +Nc1ccc(C(=O)N2CCN(c3ccccc3F)CC2)cc1 +Cc1cnc(C(=O)Nc2ccc3c(c2)Cc2ccccc2-3)cn1 +N#CCCN(C(=O)c1cscn1)c1ccccc1F +Oc1cccc(Cn2ccnc2-c2ccc(F)cc2)c1 +C=CCNC(=O)NC(c1ccc2c(c1)OCCO2)C(C)C +NC(=O)CCN1C(=O)C2C3CC4C(OC1C42)C3O +c1cnc(N2CC3CCC(C2)N3Cc2nccs2)nc1 +CCC(C)(C)C(=O)NC(C)C(=O)N1CCCCC1 +O=C(CCC(=O)N1CCN(c2ccccn2)CC1)N1CCCC1 +Cc1ccc(NS(=O)(=O)c2ccc3ncccc3c2)c(C)c1O +O=C(NCCC(=O)N1CCNCC1)c1ccccc1F +CCc1ccc2oc(C(=O)Nc3nnc(C)s3)c(C)c2c1 +Cc1nc(CC(=O)Nc2ccc3c(c2)nc(C(C)(C)C)n3C)cs1 +CCOc1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1OC +CCC(C)C(C)NC(=O)NCc1ccc(OC)cc1OC +c1cncc(COc2ccc(-c3noc(-c4cnccn4)n3)cc2)c1 +CC(C)N(C)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +O=c1cc(C2CCC2)ncn1Cc1cc(Cl)cc2c1OCOC2 +CCC(Nc1nc2ccccc2o1)c1cccc(S(N)(=O)=O)c1 +CCn1c(C(=O)NCc2ccccn2)cc2sccc21 +CC(=O)N1CCCC(C(=O)NCC(c2ccccc2)C(C)C)C1 +CC(C)CC1COCCN1C(=O)c1cnc(C2CCCO2)s1 +O=C(c1ccc(F)c(C(F)(F)F)c1)N1CCCC(n2cncn2)C1 +CCc1cccc(NC(=O)Cn2cc(C(F)(F)F)ccc2=O)c1 +Cc1ccc(OC(C)CNC(=O)CCn2c(C)c(C)sc2=O)cc1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)C1CC(=O)N(C2CC2)C1 +CN(Cc1cnc2ccccn12)C(C(N)=O)c1cccc(F)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1cc(Cl)ccn1 +Cc1cc(C)n(CCC(=O)N2CCC(CO)CC2)n1 +CS(=O)(=O)c1ccc(-c2ccc(N)c(F)c2)cc1 +Cc1cccc(OCC(=O)Nc2cc(N3CCC(C)CC3)ncn2)c1 +CC(C)COc1ncc(CNC(=O)C2CC(=O)N(C)C2)cc1Cl +C#CCOC(=O)c1csc(-c2ccc(OCC)cc2)n1 +CCN(CC)C(=O)c1cc(C(=O)NC2CCCCC2C)n(C)n1 +NC(=O)CCC(=O)N1CCCC(COc2cccc(F)c2)C1 +Nc1cnc2nc(-c3ccc(Br)cc3)oc2c1 +CCn1cc(-c2cn(CCOc3ccccc3)nn2)cn1 +CCOC(=O)N1CCN(CCCOc2ccccc2)CC1 +CC(NC(=O)c1cc(Cl)c2c(c1)OCCO2)C1CC1 +Cc1ccc2c(NC(=O)COc3ccc(F)cc3)cccc2n1 +O=C1CCCc2c1cnn2-c1ccccc1Br +Cc1cnc(C(C)(C)NC(=O)c2cccc(OCC(F)F)n2)s1 +Cc1nn(C)c(C)c1CCc1nc(-c2ccc3nc[nH]c3c2)no1 +CCOC(=O)Cc1ccccc1NC(=O)c1ccc(F)c(F)c1 +CC(=O)N1CCc2nc(-c3cccnc3)nc(N3CCOCC3)c2C1 +NC(=O)c1c(NC(=O)COC(=O)c2ccco2)sc2c1CCCC2 +CN(CCOCC1CC1)C(=O)Nc1ccccc1Cl +CS(=O)(=O)N1CCC(OCc2nc(-c3ccncc3)no2)CC1 +CNc1ccc(NS(=O)(=O)c2c(C)noc2C)cc1 +CCCNC(=O)CNC(=O)Nc1ccc(Oc2ccc(C)cc2)nc1 +CC(=O)c1noc(-c2cccc(Br)c2)n1 +COc1ccc2cc(CN(C)C(=O)CC(C)C)c(=O)[nH]c2c1 +Cc1cc(C)n(CCC(=O)Nc2cccn3nc(C)nc23)n1 +Cc1nc(C)c(CC(=O)OC(C)C2CCCCC2)c(=O)[nH]1 +N#Cc1cc(F)ccc1CSc1ccccc1N +Cc1ccc(NC(=O)CCC(C)C#N)c(Br)c1 +O=C(Cc1ccon1)N1CC2OCCN(Cc3ccccc3)C2C1 +O=C(Cc1cccnc1)Nc1cncnc1N1CCCC1 +CC(C)C(NS(=O)(=O)c1ccccc1)C(=O)N1CCCCC1 +CC1CCC(NC(=O)COc2ncnc3sccc23)CC1 +CCOc1ccc(OCC(=O)Nc2cc(F)c(OC)c(F)c2)cc1 +CN(C(=O)c1cccc(CS(=O)(=O)c2ccccc2)c1)C1CC1 +Cc1nc(NC(=O)c2ccc(N)nn2)sc1C(=O)N(C)C +CCCn1cc(C(=O)NC(CC(C)C)C(N)=O)c(C)n1 +CCOC(=O)C(C)NC(=O)c1cc(Br)cn1C +O=C(Cc1nnc(-c2cnccn2)o1)NCc1ccc(F)c(Cl)c1 +CCCOc1ccc(CNC(=O)c2cccc(-n3cnnn3)c2)cc1 +COC(=O)c1ccc(S(=O)(=O)NCCc2cc(C)no2)cc1 +Cc1sc(=O)n(CCOc2ccccc2C#N)c1C +CC1CCN(C(=O)C(C)Nc2cnn(C(C)(C)C)c2)CC1 +CCc1onc(C)c1NC(=O)C1COc2ccccc21 +O=C(Nc1ccccc1OCC1CC1)c1ccnc(OC2CCC2)c1 +Cn1cc(N2CC3(CCN(C(=O)c4c[nH]cn4)C3)CC2=O)cn1 +CC(C(=O)Nc1ccccc1SC1CCCC1)n1cncn1 +Cc1nc(C(=O)Nc2ccc3c(C)c(C)c(=O)[nH]c3c2)cs1 +CC(C)CC(=O)Nc1ccc(S(=O)(=O)NC(C)C)cc1 +Cc1cc(C(=O)CCC(=O)NCCN2CCOCC2)c(C)s1 +COc1ccc(F)cc1-c1cc(C(C)=O)c(=O)n(C)n1 +COc1ccccc1NC(=O)C1=C(C)Nc2ncnn2C1 +CC=CCCNC(=O)NCc1c(CC)noc1CC +CCCC(=O)N1CCCC(C(=O)N=c2[nH]c3ccccc3[nH]2)C1 +CC(=O)N1CCC(c2ccc(-c3ccccc3)cn2)CC1 +CCC(C)NS(=O)(=O)c1ccc(Br)cc1OC +CN1CCOC(CCNC(=O)C(C)(C)NC(=O)c2cccs2)C1 +COc1ccc(NC(=O)NC2CC2)cc1N1CCCCC1=O +CC(=O)N(CCn1cccn1)c1nc2c(Cl)cccc2s1 +CN(Cc1nc2ccccc2[nH]1)C(=O)Nc1ccc(C#N)cc1 +N#Cc1cnc(-n2nccc2-c2ccc(Cl)cc2Cl)nc1 +CSc1cc(-c2nc(-c3ccncc3)no2)ccn1 +Cc1ccc2occ(CC(=O)Nc3nnc(C)s3)c2c1 +Cc1cccc(S(=O)(=O)NCCC(=O)N(C)C)c1 +CCOC(=O)C1CCCCN1CCC(=O)Nc1nccs1 +O=C(Cc1ccsc1)OC(C(=O)NC1CC1)c1ccccc1 +Cc1ncsc1CNC(=O)c1cccc(Oc2cnccn2)c1 +Cc1cc(=O)[nH]c2ccc(S(=O)(=O)NCc3ccco3)cc12 +Cc1ccc(S(=O)(=O)N(C)Cc2cccs2)cc1C +Cc1ccncc1NC(=O)C1(c2ccc(F)cc2F)CCOCC1 +CN(CCN(C)c1ccccc1)C(=O)c1c[nH]c2cccc(F)c12 +Cc1cnn(C2CCCN(C(=O)c3nc4nc(C)cc(C)n4n3)C2)c1 +CC1(NC(=O)CCCNC(=O)c2ccsc2)CCCC1 +O=C1OC(C(Cl)(Cl)Cl)OC2=C1CCC2 +CCNC(=O)C(N)c1cccc(OC)c1OCC +CN(C)S(=O)(=O)N(C)Cc1ccc(Cl)c(Cl)c1 +COC(=O)C1(NC(=O)c2cnn(-c3ccncc3)c2C)CCC1 +CCCC(=O)NCC1CCCN(C(=O)c2cn(C)nc2C(C)(C)C)C1 +N#CC(C(=O)c1ccc2c(c1)NC(=O)CS2)c1ccccn1 +Nc1ccc2c(n1)N(CCO)C(=O)C(c1ccccc1)O2 +Clc1cccnc1NCCCN1CCOCC1 +O=C(Cc1c(F)cccc1Cl)Nc1ccccc1C(=O)NC1CC1 +Cc1noc(C)c1CC(=O)N1CCCC(N2CCNC2=O)C1 +COc1cccc(-c2cc(CO)c(C(F)(F)F)o2)c1 +CCCCN1CCN(c2ccc3c(c2)OCO3)C1=O +Cc1ccc(Cl)cc1NC(=O)CSc1nnc(C(C)C)n1C +CCS(=O)(=O)c1ccc(NC(=O)C2CCCC2)cc1 +CS(=O)(=O)Oc1cc(-c2ccccn2)nc(-c2ccccn2)c1 +CC(C)c1ccc(C(=O)Nc2cccc(-c3cn[nH]c3)c2)cn1 +CC(COCC(F)(F)F)NC(=O)Nc1ccc(-n2cccn2)nc1 +O=C1CCc2cc(NC(=O)NCC3CCCc4ccccc43)ccc2N1 +COC(=O)c1sccc1S(=O)(=O)NCc1cccc(C)n1 +CCOc1ccc(C(=O)N2CCOCC2C2CC2)cc1 +Cc1cc(C)n(CCCNc2ncnc3c2cnn3-c2ccccn2)n1 +CCCc1cc(C(=O)NCCN2CCN(S(C)(=O)=O)CC2)[nH]n1 +CC(Cc1c(F)cccc1F)NC(=O)C(C)n1ccnc1 +CCC(=O)N(C)C1(c2nnnn2Cc2ccccc2)CCCCC1 +Cc1nc(CNC(=O)Cc2cccc(OC(C)C)c2)c(C)s1 +CS(=O)(=O)N(CC(F)(F)F)C1CCOCC1 +COc1ccc(C)cc1NC(=O)C1CCCN(S(C)(=O)=O)C1 +COc1ccc(CC(=O)Nc2nnc(-c3ccco3)o2)cc1OC +CCCCCCNC(=O)N1CCC(NS(C)(=O)=O)CC1 +CC(=O)c1cccc(OC(C)C(=O)N(C(C)C)C2CCOCC2)c1 +CC(C)CCOC(C)C(=O)Nc1ccc(N)cc1Cl +COC(=O)Cc1ccccc1NC(=O)COc1ccccc1F +CCCN(Cc1cc(-c2cccc(OC)c2)on1)C(=O)CC +COc1ccc2cc(CNC(C)C(=O)NCc3ccco3)ccc2c1 +O=C(NCC1COc2ccccc2O1)C12CC3CC(CC(O)(C3)C1)C2 +O=C(CCCNC(=O)c1ccccc1)NCc1nc2ccccc2[nH]1 +CC(C)Cc1c(C#N)nnn1-c1ccc(Cl)cc1 +CN(C)c1cccc(C(=O)N(Cc2ccsc2)Cc2ccco2)c1 +CCC(Nc1nccc(-c2cn(C)nc2C)n1)c1ccccc1 +Cc1nn(C)c(C)c1CC(=O)NCC1(c2ccccc2)CCC1 +CS(=O)(=O)c1cccc(S(=O)(=O)NCc2cscn2)c1 +O=C(Nc1nccs1)c1cc(S(=O)(=O)N2CCCC2)cs1 +Cc1cc(=O)[nH]c(Nc2ccc(Br)cc2)n1 +O=C(c1cccn1Cc1noc(C2CC2)n1)N1CCc2ccccc21 +Nc1ccc2cc(S(=O)(=O)CCO)ccc2c1 +CCc1ccc(S(=O)(=O)N2CCOC3CCCCC32)s1 +Cc1ccc(C(O)CCNc2cccc(C#N)c2)cc1C +CNC(=O)CCN(Cc1ccccc1C(F)(F)F)C1CC1 +CC(=O)Nc1ccc2c(c1)nc(C)c(=O)n2Cc1ccccc1 +Cc1ccc(CNc2nc3ccccc3n3c(C)nnc23)cc1 +Cc1nnc(SC(C)C(=O)Nc2cc(F)ccc2F)n1N +CCC(CC)C(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O +CC(C)c1ccc(C2CCCN2C(=O)C2CC(=O)N(C)C2)cc1 +COc1ccccc1-c1cnc(CN2c3ccccc3CC2C(N)=O)o1 +Cc1n[nH]c(C)c1C1Nc2ccccc2C(=O)N1Cc1ccco1 +CCC(CC)NS(=O)(=O)c1cccc(C(C)=O)c1 +C=C(C)COc1cccc(NC(=O)N2CCCC2)c1 +COc1ccccc1OC1CN(C(=O)C2COCCO2)C1 +CCCCS(=O)(=O)N1CCC(c2nc3ccccc3s2)CC1 +COC(=O)C1CCCCN1C(=O)c1cnn(-c2ccncc2)c1C +CSc1cc(C(=O)NCCCN2CCCC2=O)ccn1 +CCOc1ccc(-n2nnc3c2SCC3(O)c2ccccc2)cc1 +COC(=O)c1nnc2sc(-c3cccc(F)c3)nn12 +CC1(C(N)=O)CN(C(=O)CN2CCCCCC2=O)CCO1 +O=C(C1CCCCC1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +Cc1ocnc1C(=O)N(C)CCN(C)C(=O)OC(C)(C)C +O=C(c1ccc(Cl)cc1)N1CCCN(C(=O)c2cccnc2)CC1 +COc1cccc(S(=O)(=O)CCSc2ccccc2OC)c1 +CC(C)NC(=O)c1ccc(NCc2nc(-c3ccsc3)no2)cc1 +COc1cccc(N2CCN(C(=O)N3CCOCC3)CC2)c1 +Cc1cccc(OCC(C)NC(=O)NCc2ccc(C(N)=O)cc2)c1 +CC(C)N(C)C(=O)c1ccc(CNc2ncnc3c2cnn3C)cc1 +CCc1nc(CNc2cc(S(=O)(=O)N(C)C)ccc2OC)no1 +COC(=O)c1ccsc1NC(=O)c1oc2ccc(OC)cc2c1C +O=C(C1CCCC1)N1CCCC1c1ccc2c(c1)OCO2 +O=C(Nc1ccc(F)cc1)c1c[nH]c2c(F)cccc2c1=O +Cc1cc(C)n2cc(CN(C)Cc3ccc(C(F)(F)F)cc3)nc2n1 +CC(=O)NC(C)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1C +CCS(=O)(=O)N1CC(c2nc(C)no2)CC2OCCC21 +CNS(=O)(=O)c1ccc(C(=O)Nc2ccc(C(C)=O)c(C)c2)cc1 +CCN(Cc1cccc(F)c1)C(=O)c1ccc(-n2cccn2)cc1 +CCCCNC(=O)Cc1csc(NC(=O)c2ccsc2)n1 +COc1cc(C(=O)N(C)CC(=O)Nc2c(C)cc(C)cc2C)ccn1 +O=C(Nc1ccccc1)C1CCCN1C(=O)Nc1ccc(F)cc1 +COc1c(O)c(OC)c2c(c1SC)COC2=O +CCCC(NC(N)=O)C(=O)N1CCC(Cc2cccc(F)c2)CC1 +Cc1cc(C)c(NC(=O)NCc2cnn(C)c2)c(C)c1 +CC(CNC(=O)COc1cccc2c1OC(C)(C)C2)Cn1cccn1 +O=C(CNc1cnc2ccccn2c1=O)N1CCOCC1 +O=C(Cn1cnnn1)N(Cc1cccc2ccccc12)C1CCCC1 +Nc1c(-c2cccs2)nc2scc(-c3ccco3)n12 +O=C(Cc1cccs1)N1CCCC1c1ccncc1 +CC1CCCC(NC(=O)CCC(=O)NCc2ccccc2)C1C +COc1ccc(NC(=O)CCn2c(=O)oc3ccccc32)cc1 +O=C(NCc1ccncc1)c1csc(-c2cccs2)n1 +COc1c(C(=O)NCCc2cccc(Cl)c2Cl)c(C)nn1C +CC(OC(=O)c1ccsc1)C(=O)NCCc1ccccc1 +CCCOc1cc(OC)cc2c1CCNC2CC#N +O=c1oc2cccnc2n1CCOc1ccc(Cl)cc1Cl +O=C1CN(c2ccncn2)CCN1C1CCCCC1 +COc1cc(SC)ccc1C(=O)Nc1cccnc1 +O=c1c2ccc(F)cc2ncn1CCc1ccccn1 +CN(CCOc1ccccc1)C(=O)CN(C)c1ncnc2[nH]cnc12 +COc1nn(C)cc1C(=O)N1CC(C)CC(C)C1 +Cc1ccc(C(=O)N2CCN3C(=O)C4CCCN4C(=O)C3C2)cc1F +CC(=O)Nc1cccc(C(=O)OCC(=O)NC2CC2)c1 +CC(C)(C)C1CCc2sc(C(=O)NCCO)cc2C1 +C=C(C)CN(CC)S(=O)(=O)c1ccc2c(c1)OCCO2 +COC(=O)c1ccoc1CN1CC(C)OCC1C +COc1ccc(F)cc1C(O)CCC(=O)NC(C)C +CC1CC(C)CN(C(=O)NCc2cnn(C)c2)C1 +CC(C)C(=O)Nc1ccc(NC(=O)C2CCCO2)cc1 +CCCOc1c(Cl)cc(C(=O)Nc2nonc2C)cc1OCC +N#CCC(=O)Nc1ccc(C(=O)OCc2ccccc2Cl)cc1 +Cn1nnnc1NCc1cc(Cl)ccc1OCC(N)=O +CN(CC(O)C1CC1)C(=O)c1ccc(Br)c(F)c1 +COc1ccnc(N2CCN(C(=O)Cn3nc(C)cc3C)CC2)n1 +CCN(CC(C)C#N)C(=O)c1ccc(-n2cccc2)cc1 +CS(=O)(=O)N1CCOC(CNc2nccc(-c3ccncc3)n2)C1 +Cc1nn(C)c(C)c1C(=O)N(C)Cc1ccncc1 +COC(=O)C(NC(=O)C(C)Sc1ccccc1Cl)C(C)C +Cc1nn(-c2ccc(C(=O)NCc3ccncc3)cc2)c(C)c1Cl +COCCOc1ncccc1C(=O)Nc1cc(C)nn1C +CC1CCC(O)(CN2CCN(C(=O)CN3CCOCC3)CC2)CC1 +Cc1cc(C)c(NC(=O)CSc2nn3cnnc3o2)c(C)c1 +CCn1nc(C(=O)NCc2ccco2)cc1-c1cc(C)sc1C +Cc1ncc(C(=O)N2CCN(Cc3cccc(F)c3)CC2)s1 +Cn1cc(NC(=O)C2CCN(S(C)(=O)=O)CC2)cn1 +CN(C)S(=O)(=O)c1cccc(COC(=O)c2ccsc2)c1 +Cc1nc(-c2cccc(Cl)c2)sc1C(=O)NCc1cc[nH]n1 +CC(C)C(NC(=O)c1cccs1)C(=O)Oc1ccccc1 +O=C(Cn1cccc1)N1CCC(S(=O)(=O)c2ccccc2)C1 +Cc1ccc(CC(=O)NCCOCC(F)(F)F)cn1 +CC(C)CCC(=O)N(C)Cc1nccn1C(F)F +Cc1ccccc1NC(=O)c1cccc2c(=O)c3c([nH]c12)CCCC3 +CCCOc1ccccc1NC(=O)N1CCN(C(=O)C(C)(C)C)CC1 +Cn1ncc2c1CCCC2Nc1ncnc2c1cnn2CCO +Cn1cccc(NC(=O)NC(c2cccs2)C(C)(C)C)c1=O +C#CCSc1nnc(-c2ccc(=O)n(Cc3ccccc3)c2)o1 +O=C(Cc1ccccc1Cl)NCC(O)C1CC1 +Cc1cccc(OCCNC(=O)CSc2n[nH]c(=O)n2C)c1 +COc1cccc(NCC(O)c2cc(F)ccc2F)c1 +O=C(c1cnccn1)N1CCC2(CCNC2=O)CC1 +O=C(Nc1cnc(-c2ccc(Cl)cc2)nc1)C1CCCO1 +CNC(=O)C(NC(=O)c1ccc2nccn2c1)C(C)C +CC1CC(C)CN(C(=O)NC2CCN(C(=O)c3ccco3)CC2)C1 +CN(c1ccccn1)S(=O)(=O)c1cccc(-n2cnnn2)c1 +CC1Oc2ccc(CC(=O)NCCO)cc2N(C)C1=O +O=C(CNC(=O)N(Cc1ccco1)Cc1ccco1)N1CCCC1 +COCC(C)N1CCN(C(=O)Nc2ccccc2F)CC1 +Cc1cc(COC(=O)c2cccnc2Nc2ccccc2F)on1 +CN(C)S(=O)(=O)N(CC(N)=O)c1ccccc1 +O=S(=O)(NCC(O)c1ccccc1)c1ccc(F)cc1 +CC(NC(=O)Cn1ccsc1=O)c1ccc2ccccc2c1 +CC1(CCNC(=O)Nc2cc(-c3ccco3)ccc2F)OCCO1 +O=C(COc1ccc(-n2cnnn2)cc1)NCc1ccc(F)cc1 +Nc1cccc(OCCNC(=O)Cc2ccccc2)c1 +CC(C)CCOC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +COc1ccc(-c2cc(C(=O)NCc3cc(F)cc(F)c3)n[nH]2)cc1 +CCn1ncc(Cl)c1C(=O)n1nc(C)cc1C +COc1ccc(-c2nc(COn3nnc4ccccc43)co2)cc1 +CC(C#N)(NC(=O)CN1CCOCC1C1CC1)C1CC1 +COC(=O)CNC(=O)c1nn(C)c(C)c1Br +CCCC(C)N(C)C(=O)Nc1ccc(C(N)=O)cc1C +O=C1CCN(C(=O)c2ccc3ccccc3c2)CC1 +N#CCCN(CCN1CCOCC1)C(=O)c1ccc(F)cc1F +C#CCNC(=O)Nc1c[nH]c2c(Cl)cccc2c1=O +Cc1cc(NC(=O)CNc2ccccc2Cl)on1 +O=C1OCCN1CCc1nc(Cc2ccccc2)cs1 +Cc1cccc(C)c1NCC(=O)N(C)CCOc1ccccc1 +CC1OCCN(C(=O)Nc2cc(Br)c(=O)n(C)c2)C1C +Cc1cc(C)n(-c2ncc(NC(=O)Cc3ccc(Cl)cc3)cn2)n1 +C#CCNc1ccc(S(=O)(=O)NC(C)C)cc1 +COc1cccc(NC(=O)COC(=O)Cc2ccc(C)cc2)c1 +Cc1ccc(NC(=O)c2nn(-c3ccccc3)ccc2=O)cc1 +Cc1noc2ncc(C(=O)NCCCN(C)S(C)(=O)=O)cc12 +Cc1nsc(C(=O)N2CCN(CCc3ccccc3)CC2)n1 +CCOC(=O)C(C)(C#N)c1cc(OC)cc(OC)c1 +CCOC(=O)C1=C(N)Oc2[nH]nc(C)c2C1c1ccc(Cl)cc1 +COc1ccc(N2CCN(C(=O)c3ccccc3SC)CC2)nn1 +COC(=O)c1cc(NC(=O)C2CCCN2S(C)(=O)=O)ccc1F +Cc1cc(C(=O)N(C)Cc2cc(Br)ccc2F)on1 +CC(=O)Nc1ccccc1C(=O)Nc1cc(Cl)ccc1C +CNS(=O)(=O)c1ccc(-n2ncc(Cl)c(Cl)c2=O)cc1 +CCCCS(=O)(=O)Nc1ccc2c(c1)CC(=O)N2CC +CC(=O)Nc1nc(CNc2c(C)cccc2C(N)=O)cs1 +Cc1c(Cl)ccc2c(NC(=O)c3ccncc3)ccnc12 +CCOC(=O)C1CCCN(C(=O)c2cccc(-n3cnnn3)c2)C1 +Cc1cc(CN2CCN(C(=O)c3c(C)noc3C)CC2)on1 +CC(c1cccc(Cl)c1)N(C)C(=O)c1ccc(=O)n(C)n1 +CC(OCC1CC1)C(=O)N1CCSc2ccc(Cl)cc21 +Cc1ccc2ncc(C(=O)N(C)c3ccccc3)n2c1 +COC(=O)N1CCc2c(sc(NC(=O)C3CCCCC3)c2C#N)C1 +COCC1CCCN1C(=O)Cc1cccc(OCC#N)c1 +O=C(NCC1(O)CCc2ccccc2C1)C1(c2cccs2)CC1 +Cc1cnc(C(=O)Nc2cccc(COC3CCCC(C)C3)c2)cn1 +COc1ccccc1-c1ocnc1C(=O)Nc1cccnc1 +CCS(=O)(=O)NCc1ccnc(Oc2ccc(F)cc2)c1 +Cn1cc(Cl)c(C(=O)Nc2cn(C)nc2C(N)=O)n1 +CS(=O)(=O)N(CC(=O)NCCN1CCOCC1)c1ccccc1 +CCOC(=O)CC(C)CNC(=O)Nc1ccc(C)cc1 +CCCc1cc(C(=O)N2CCN(CC(C)(C)O)CC2)[nH]n1 +CCOc1ccc(C(=O)NCc2ncc(-c3ccccc3)[nH]2)cn1 +CCN(CC(=O)OC)S(=O)(=O)c1ccc(C)cc1 +O=C(NCC(F)(F)F)c1cnc(Cc2ccc(F)cc2)s1 +CCC(C)(C)NC(=O)C1CCCN(C(=O)Nc2ccccc2F)C1 +CN(C(=O)c1cccc(F)c1)C(C#N)c1ccco1 +CCOC(=O)c1cccc(N2C(=O)c3ccccc3S2(=O)=O)c1 +NC(=O)COc1ccc(C(=O)c2ccc(Cl)cc2)cc1 +CCCC(=O)NCC(=O)Nc1nc(C(F)(F)F)cs1 +CCCn1nc(C(=O)Nc2cc(Cl)ccc2C(N)=O)ccc1=O +CC(C)c1cccc(N(C)C(=O)CCC(=O)Nc2nccs2)c1 +Cc1cnc(CNC(=O)N(C2CC2)C(C)c2ccco2)s1 +CC(=O)Nc1ccc(SCC(=O)N(C)Cc2ccc(C)o2)cc1 +CCOC(=O)c1cnc(NCc2cncnc2)s1 +C=CCNC(=O)c1cc(-c2cc(OC)ccc2OC)on1 +Cc1cccc(C)c1OCCCNC(=O)c1cc[nH]n1 +COC(=O)c1ccc(C(=O)NCCS(N)(=O)=O)s1 +COCn1nc(C#N)cc1-c1ccc2c(c1)OCCCO2 +CCn1cc(C(=O)Nc2ccc(OC(F)F)c3ncccc23)cn1 +CC(=O)Nc1ccc(C(=O)OC2CCCCC2=O)cc1 +CC(=O)N1CCN(C(=O)CNC(=O)CC(C)(C)C)CC1 +Cc1ncc(CN(C)C(=O)c2c(C)n[nH]c2C)s1 +COc1ccc(Cc2nc3ccc(F)cn3c2C#N)cc1OC +CC1CCC(C)N1C(=O)c1c(O)cccc1CCc1ccc(O)cc1 +Cc1noc(COC(=O)C2CC(=O)N(CCc3ccccc3)C2)n1 +Cc1cc(=O)n(CC(=O)NC(C)Cc2ccccn2)c2ccccc12 +Fc1ccc(C2NCCc3ccc4c(c32)CCO4)nc1 +CC1(OC(=O)c2ccc(-n3cnc4ccccc43)nc2)CCC1 +Cc1c(C(=O)NC2CCC(O)CC2)oc2c(Cl)cccc12 +Cc1nc(CNc2cccc(NC(=O)c3ccccc3)c2C)no1 +COc1cc(C2CC(=O)Nc3c2c(C)nn3C)ccc1O +Cc1n[nH]c(C(C)C)c1C(=O)NCc1ccnc(OC(C)(C)C)c1 +O=C(CCn1nnc2ccccc2c1=O)Oc1ccccc1 +Cc1cc(C)n(-c2cccc(NC(=O)CSc3ccncc3)c2)n1 +COc1ccc(NS(=O)(=O)c2ccc(F)c(Cl)c2)cc1OC +Cc1ccn2cc(C(=O)Nc3cccc(N4CCCC4=O)c3)nc2c1 +COc1cc(CNC(=O)CC(C)C)cc(OC)c1O +COc1ccccc1S(=O)(=O)N(C)Cc1ccccc1F +Nc1nsc(-c2ccc(Br)cc2)n1 +CC(Sc1nc(N)nc(N)n1)C(=O)Nc1ccccc1Cl +O=C(Cn1cccn1)NC1CC(=O)N(C2CCCCCC2)C1 +CCC(NC(=O)CCC(=O)OC)c1cccs1 +COCCOC(=O)c1ccc(-n2nc(C)cc2C)cc1 +CN(Cc1cnn(C)c1)C(=O)COc1ccc2c(c1)CCC2 +Cc1nc(C(=O)N2CCC(c3ccc(F)c(F)c3)CC2)c(=O)[nH]c1C +CCn1c(SCC(=O)N2CCCC(C)C2)nc2ccccc21 +C#CCN(Cc1ccco1)C(=O)Cc1cccc(OC)c1 +c1ccc(N2CCc3nc(NCCN4CCOCC4)ncc32)cc1 +Cc1ccc(F)cc1CC(=O)N(C)CCc1scnc1C +CC(C)c1ccc(N2CCC(C(=O)NCc3cccnc3)C2=O)cc1 +C=CCN(Cc1ccc(F)cc1)C(=O)C(C)NC(C)=O +O=C1CCN(c2cccc(Br)c2)C1=O +CCOc1cccc(C(O)CNc2cc(C)ccc2OC)c1 +COc1ccccc1CNC(=O)COc1ccc(C#N)cc1OC +Cc1nc(-c2ccc(CC(=O)Nc3ccccn3)cc2)cs1 +CN(C(=O)c1cnc2snnc2c1)c1ccccc1 +O=C(NCC(=O)N1CCN(c2ccc(Cl)cc2)CC1)C1CCC1 +COCC(=O)OCc1cc(=O)oc2cc3c(cc12)CCC3 +CCCCCC(=O)N1CCN(C(=O)c2ccccc2)CC1 +Cc1nc(NCc2cnn(C)c2)c2c(-c3ccccc3)csc2n1 +C#CCC(OC(=O)c1cccc(OCC)c1)c1ccccn1 +N#Cc1cccc(NC(=O)CS(=O)(=O)c2ccc(F)c(F)c2)c1 +Cc1ccc(CNC(=O)NC(C)c2ccncc2)cc1F +COc1ccc(CCCNS(=O)(=O)N2CCCC(C)C2)cc1 +CN(C)C(=O)NCCNS(=O)(=O)c1cc(F)c(F)cc1F +CCN(CC)C(=O)C1=C(C)Nc2nnnn2C1c1cccc(F)c1 +Cc1cc(N2CCC3(CCC(=O)N(CCO)C3)CC2)nc(N(C)C)n1 +Cc1csc(SCC(=O)N2CCn3c(C(N)=O)cnc3C2)n1 +COc1ccc(CC(=O)Nc2cccc(-c3ccc(CO)o3)c2)cc1 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+O=C(CCNS(=O)(=O)c1cccnc1)N1CCCc2ccccc21 +Cc1ccc(CN(C)C(=O)COc2cccc(Cl)c2)o1 +Cc1nc2n(c(=O)c1C)C(CC(=O)NCCc1ccccc1)CS2 +CCc1cc(N)c2onc(CC(=O)NCC(C)O)c2c1 +Cc1c(C)n(Cc2ccccc2)c2ncnc(NCc3ccccn3)c12 +CCOC(=O)Nc1ccc(NC(=O)c2n[nH]c3ccc(C)cc23)cc1 +CC1CN(C2CCN(C(=O)c3cc4ccccc4n3C)CC2)CCO1 +Cc1nc2ccc(NC(=O)NCC(=O)NC3CC3)cc2s1 +CC(C)(CNC(=O)NCc1ccc2c(c1)OCCO2)N1CCOCC1 +CCCCc1nnc(NC(=O)c2cn[nH]n2)s1 +O=C1CCCN1c1cccc(CNc2nccc(C(F)(F)F)n2)c1 +Cc1cccc(C(=O)N2CCCC2)c1NC(=O)COCC1CC1 +O=C(OCc1ncn(-c2ccccc2)n1)c1cccnc1 +CCCCCCNC(=O)c1cc2cccc(N)c2[nH]1 +OC(c1cccc(F)c1)c1cnc2ccccc2c1 +CCc1cc(C2CCCN2C(=O)Nc2ccccc2OC)on1 +O=C1COc2cc(S(=O)(=O)N3CCCC3)c(Cl)cc2N1 +CCOC(=O)CCC(C)NC(=O)c1ccc(C)cc1O +COc1ccc(S(=O)(=O)N(C)CC(C)O)cc1 +CS(=O)(=O)N1CCN(c2ncccc2C(N)=O)CC1 +Cc1ccc(C(=O)NCc2nnnn2-c2ccc(F)cc2)cc1 +CN1CCN(C(=O)CCOc2ccccc2N)CC1 +CC1COCC(C)N1Cc1cc(-c2ccccc2)[nH]n1 +O=C(Nc1ccccc1C(=O)N1CCOCC1)C1CC=CC1 +CCc1nsc(NCc2cccc(C(=O)N3CCOC(C)C3)c2)n1 +COc1cc(C(=O)NCc2ccc(F)cc2)cc2occc12 +CC(C)C(C)NC(=O)c1ccc(Br)c(S(C)(=O)=O)c1 +O=C(Cn1cccn1)c1ccc(Cl)cc1Cl +CC(CNC(=O)N(C1CC1)C(C)c1ccco1)Cn1cccn1 +COc1ccc(OCC(O)Cn2nc(-c3ccco3)oc2=O)cc1 +COC(=O)N1CCC(NC(=O)NC2CCCCC2C(C)(C)C)CC1 +Cc1cnn(CCCNC(=O)Nc2ccc(F)c(Cl)c2)c1 +Cc1ccccc1C1CNCCN1C(=O)OC(C)(C)C +Cc1c(NC(=O)c2ccncc2F)cccc1C(F)(F)F +Cc1ccccc1COC1CCN(C(=O)Cc2ccc(O)cc2)CC1 +Cn1nc(C(=O)Nc2ccccc2N2CCc3ccccc32)ccc1=O +Cn1cc(C(=O)N2CCN(c3nc4ccccc4s3)CC2)cn1 +O=C(CCn1cc(Cl)cn1)NCc1ccccc1 +CC(C)n1cnnc1SC(C(=O)N1CCCCC1)c1ccccc1 +COC(=O)c1cccc(CCNC(=O)c2cccnc2OC)c1 +CN(CC1CCCO1)C(=O)c1nc(-c2ccccc2)oc1C1CC1 +Cn1cc(C(=O)OCCC(F)(F)F)c(-c2cccs2)n1 +CSc1nc(C)cc(C(=O)NCC(=O)N2CCCCC2)n1 +CCOC(=O)CC(C)CNC(=O)Nc1ccc(C)cc1Cl +COCCN1CCN(Cc2cn3ccccc3c2C#N)CC1=O +CC(C)NS(=O)(=O)c1cccc(CNC(=O)CC2C=CCC2)c1 +Cc1nc(CC(=O)N2CCCc3c(C(N)=O)cccc32)cs1 +O=C(CC(c1ccccc1)c1ccc(Cl)cc1)NCc1ncc[nH]1 +O=C(NCCOc1cccc2cccnc12)c1cc2sccn2c1 +COc1ccc(C(=O)Nc2nc(CC(=O)NC3CC3)cs2)cc1 +CC(C)NC(=O)NCc1cn(-c2ccccc2)nn1 +Cc1noc(C)c1NC(=O)CCSc1ccccc1F +CC(C)C(=O)NCCNC(=O)c1n[nH]c2ccccc12 +O=c1oc2cccnc2n1CCSc1ccc2c(c1)OCCCO2 +Cc1cc(C(=O)N(C)Cc2cccs2)c(C)n1Cc1ccccc1 +CCNC(=O)CNC(=O)Nc1ccc(Br)cc1C +COCCCN(C)C(=O)Nc1cccc(Cl)c1C +CC(C)CNC(=O)c1c(-c2ccccc2)cnn1C +CCCOC(=O)C(C)Sc1nnc2cc(C)nc(C)n12 +CCCc1nnc(NC(=O)N(C)Cc2ccc(C(=O)OC)cc2)s1 +COc1ccccc1CNC(=O)c1cc2cnc3[nH]ccc3c2s1 +CCC(NC(=O)NCC(C)CC(C)O)c1ccc(F)cc1F +CC(C)(CO)NC(=O)c1ccc(-c2ccc(Cl)cc2)o1 +COc1ccc(Cl)cc1-n1nnc(C#N)c1C(C)C +COc1ccc(C(=O)NCCNC(=O)Nc2cc(F)ccc2F)cc1 +CCc1noc(CC)c1CC(=O)NCC(C)N1CCOCC1 +COc1ccc(C(C)=O)cc1CC(=O)NCc1ccc2c(c1)OCO2 +N#Cc1ccccc1C(N)c1nnc(-c2ccncc2)o1 +Cn1cnnc1SCc1cc(-c2ccc(Cl)cc2)no1 +O=C(Cn1cnnn1)N1CCC(c2ccc(F)cc2)C1 +CCN(CC1CCCO1)C(=O)c1ccc(-c2cscn2)cc1 +Cc1ccc(C(C)NC(=O)Cn2cnc3c(cnn3C)c2=O)o1 +COc1ccc(CCC(C)NC(=O)C(C)NC(N)=O)cc1 +CCn1cc(NC(=O)c2cc(-c3ccccc3)nc3ncnn23)cn1 +CCOCCNC(=O)c1csc(-c2ncccn2)n1 +O=C1CCN(C(=O)CC(c2ccccc2)c2ccccc2)CC1 +CCOc1ccc(CCNS(=O)(=O)c2ccccc2)s1 +CCN(CC)C(=O)Cn1c(=O)cc(C)c2ccccc21 +Cn1ccnc1-c1cc(F)cc(Br)c1 +CC(C)C(=O)Nc1ccc(NC(=O)NC(C)(C)CO)cc1 +Nc1cccc(OCCCn2c(=O)oc3ccccc32)c1 +CC(=O)N1CCC(NC(=O)Nc2ccc(Cl)cc2-n2cccc2)C1 +Cc1nc2ccccc2c(-c2ccccc2)c1C(=O)N1CCOCC1 +COc1ccccc1CN(C(=O)NCCN1CCOCC1)C1CC1 +CCN(CC)C(=O)CNC(=O)c1cnc(-c2ccccc2)nc1 +N#Cc1cccc(CNCCc2ccc(-n3cccn3)cc2)c1 +Fc1cccc(Cc2nnc(-c3ccncc3)o2)c1 +Cc1cnc(C(C)(C)NC(=O)Nc2cnn(C(C)(C)C)c2)s1 +CCOC(=O)c1nn(-c2ccccc2)c2ccccc2c1=O +CC(C)C(C)(C#N)NC(=O)COC(=O)Cc1ccc(F)cc1 +CC(C)OC(=O)c1cc(-c2ccc3c(c2)CC(=O)N3C)nn1C +Cc1cc(C(=O)N2CCC(n3ccc(C(F)(F)F)n3)CC2)on1 +Nc1cc(NC(=O)Nc2ccc(F)cc2)ccc1Cl +COC(=O)C(C)NS(=O)(=O)c1cccc(Br)c1 +Cc1ccc(NC(=O)CSc2nccn2C)c(N)c1 +Cc1cc(NC(=O)COC(=O)C(C)(C)Oc2ccc(F)cc2)no1 +N#Cc1ccc(OCCn2cnc3sccc3c2=O)cc1 +O=C(COC(=O)c1ccccn1)Nc1ccc(OC(F)F)cc1 +O=C(CCCc1cccs1)N1CCN(c2ccccc2O)CC1 +CCOC(=O)C1CCCN(C(=O)c2ccc(C)nc2)C1 +COc1ccc(C(O)CCCC(=O)NC(C)C)cc1 +CCn1c(C)cc(C(=O)Nc2cccc(NC(=O)OC)c2)c1C +COC(=O)c1ccc(C(C)Sc2nnnn2-c2ccccc2)o1 +Cc1nnc(NC(=O)C2CCN(CC(F)(F)F)CC2)s1 +Cc1nnc(-c2ccc3ccn(CC(=O)N4CCCCC4)c3c2)o1 +CC(C)c1nnc2sc(C=Cc3ccc4c(c3)OCO4)nn12 +COc1ncccc1CN1CCN(c2noc(C(C)C)n2)CC1 +Nc1ccc(Oc2cccc(C(F)(F)F)c2)cn1 +CC(CC#N)NC(=O)c1sccc1OC(F)F +COc1ccccc1CN(CCO)C(=O)Nc1cc(F)ccc1OC +Cc1ccc(CC(=O)Nc2ccccc2NC(=O)N2CCCC2)cn1 +COc1ccccc1-c1csc(NCc2ccco2)n1 +CCCCOC(=O)c1ccc(-n2nc3ccc(N)cc3n2)cc1 +NC(=O)COC(=O)CCNC(=O)c1ccc(Br)cc1 +COc1ccc(CCNC(=O)Cn2cnnn2)cc1 +CCc1cc(N2CCCC(C(=O)c3ccccn3)C2)n2nccc2n1 +CC(C)(C)NC(=O)NC1CCN(C(=O)c2cnn3c2OCCC3)C1 +Cc1cc(C)nc(SCC(=O)Nc2cccnc2)n1 +N#Cc1ccc(C(F)(F)F)c(NCc2ccc(C(N)=O)cc2)c1 +Cc1ccc(C(O)CCC(=O)NCC2CCCO2)c(C)c1 +Cc1ccc(C(CNCc2cccn2C)N2CCOCC2)s1 +COc1ccc(-n2ccnc2SCC(=O)N2CCC2)cc1 +CCC(C)(C)NC(=O)COC(=O)c1cc(C)n(C(C)C)c1C +NCC(=O)OCC1c2ccccc2-c2ccccc21 +CN(CCN(C)C(=O)c1ccc(=O)n(C)c1)C(=O)OC(C)(C)C +CCN(C(=O)CNC(=O)c1ccc(C)s1)C(C)COC +C=CCCCN(C)C(=O)c1cnn2c(-c3ccccc3)ccnc12 +Cc1nc2ccc(Cl)cc2cc1C(=O)OCC(=O)C1=NC=CC1 +OC1CCC(Nc2nc(C(F)(F)F)nc3ccc(F)cc23)CC1 +CC(c1ccco1)N(C)C(=O)Nc1ccccc1N(C)C +CCC(=O)c1ccc2c(c1)N(CC(=O)N1CCCCCC1)C(=O)CO2 +Brc1ccc(Nc2ccccn2)nc1 +CC1(C(=O)N2CCOC(Cc3ccc(F)cc3)C2)CC1 +CC(C)(NC(=O)CCC(=O)c1ccc(F)c(F)c1)c1nccs1 +Cc1ccccc1C(=O)Nc1nc2nc(C)c(Cl)c(C)n2n1 +Cn1ncc2c(=O)n(CCC(=O)Nc3ccc(F)cc3F)cnc21 +CCOc1cc(Cl)ccc1S(=O)(=O)Nc1cccc(O)c1 +CCC(C)n1ncc(C(=O)N(C)c2ncccc2OC)c1C1CC1 +CC(C)NC(=O)c1cn2ccnc2cc1-c1ccccc1 +Cc1cc(NC(=O)C(C)N2CCN(Cc3noc(C)n3)CC2)no1 +CCOc1ccc(Cl)c(C(=O)NCc2ccsc2)n1 +O=C(NCc1cn2cc(Cl)ccc2n1)c1cc2ccccc2o1 +C#CCOc1ccccc1CN(C)C(=O)CC1(O)CCCC1 +O=C(Cc1ccccc1F)NC1CCN(c2ccccc2)C1=O +Cc1cc(C)nc(C(=O)Nc2ccccc2C(N)=O)c1 +O=c1ccc(C(F)(F)F)nn1Cc1ccc(-n2cccn2)cc1 +CCS(=O)(=O)N1CCC2CN(c3ncccn3)CCOC2C1 +Cc1ccc(OCC(=O)Nc2c(C)nc3sccn3c2=O)c(C)c1 +Cc1cc(CNc2cccc(C(N)=O)c2)c(C)s1 +CCOCC1CCCN(C(=O)C(C)Sc2ccc(OC)cc2)C1 +Cc1nc2nc3c(c(Nc4ccc5c(c4)OCCO5)n2n1)CCC3 +O=S(=O)(Nc1nncs1)c1ccc(Br)cc1 +COc1ccc(C(=O)N2CCN(c3nnc4ccccn34)CC2)cn1 +C=C(C)CSc1nnc(NC(=O)c2ccco2)s1 +CCOc1ccc2nc(NC(=O)COCc3nc(C)no3)sc2c1 +CC1Cc2ccccc2N1C(=O)COc1ncnc2sccc12 +CCOc1ccc(C(F)(F)F)cc1NC(=O)NCCC(=O)N(C)C +O=C(CCc1conc1-c1ccccc1F)NCc1ccccc1 +CCC(CO)NC(=O)CCc1c(C)nc2c(C#N)cnn2c1C +Cc1ccccc1C1CC1C(=O)NCc1csc(C2CC2)n1 +COc1ccccc1NC(=O)C1(c2ccc(F)cc2)CCOCC1 +COc1ccc(NC(=O)c2ccc(C(F)(F)F)nc2C)cc1OC +CCCOc1ccc(-c2cnn(C)c(=O)c2N)cc1 +COc1ccc(-c2nnc(NC(=O)c3cccs3)s2)cc1OC +CC(C)CN(CC(N)=O)S(=O)(=O)c1ccc2c(c1)OCCO2 +CC1CCC(NC(=O)CNC(=O)c2ccccc2F)CC1 +CCOC(=O)N1CCN(C(=O)c2cnc(-c3ccncc3)nc2)CC1 +CC1CC1NC(=O)c1cn(C)nc1-c1ccc(F)cc1F +Cc1ncsc1CCC(=O)NCC1COc2ccccc2C1 +CCCSc1cc(Cl)cc(C)c1C(=O)NC +COC(=O)c1ccccc1C#Cc1ccccc1C(C)=O +CC(Sc1ccccc1)C(=O)Nc1cccnc1-n1cncn1 +COC(=O)CCNC(=O)COc1ccc(Br)cc1F +CCc1cccc(CC)c1NC(=O)CCc1nc(C(C)C)no1 +COCC1(C(=O)N2CCC2c2cccc(OC)c2)CCC1 +Cc1cccc(C(=O)N2CC3CCCC3(COc3ccccn3)C2)n1 +CN(Cc1cscn1)C(=O)COc1cccc(N)c1 +CCn1nc(C)c(CNC(=O)NCCc2ccc(C)nc2)c1C +Cc1[nH]c2ccccc2c1C(=O)N(C)CC(C)C#N +CC(COC1CCOC1)NC(=O)Cc1ccc[nH]1 +CN(Cc1cccc(Cl)c1)C(=O)C1CCCC1 +O=S(=O)(Cc1coc(-c2ccccc2)n1)c1ccc(F)c(F)c1 +Cc1cc(C)c(C(=O)Nc2ccc(F)c(C#N)c2)c(=O)[nH]1 +CSc1ccc(C)c(C(=O)OCc2cccc(C(N)=O)c2)c1 +CC12CCC3(C=C1CCCC21OCCO1)OCCO3 +Cn1c(=O)c2cc(C(=O)NCCCOCC3CC3)cnc2n(C)c1=O +CCOc1cc(C)ccc1CNC(=O)Cc1ccc[nH]1 +Cc1cccc(COC(=O)c2ccnc(-n3ccnc3)c2)n1 +CNC(=O)NCc1ccc(S(=O)(=O)NCCOC)cc1 +Cc1[nH]c2ccccc2c1C(=O)OCCNc1cccnn1 +Cc1nc2ccccc2n1CCc1nc(N)nc(N)n1 +CCC(=O)N1CCN(C(=O)Cc2ccc(F)c(F)c2)CC1 +CCN1CC(C(=O)NC2CCCN(c3ccccc3)C2=O)CC1=O +COC(=O)CCN(CC(C)C)C(=O)c1cc(Br)c[nH]1 +Nc1nc(=O)[nH]cc1-c1ccc(Br)cc1 +CCCCCc1nnc(NC(=O)NCc2ncn(C)n2)s1 +CCN(CC)C(=O)c1csc(Nc2cccc(C)n2)n1 +O=C(Nc1cn[nH]c1)NC1CC1c1ccccc1F +CC1CCCCN1C(=O)C1CN(C(=O)c2cccs2)C1 +Cc1cnc(COC(=O)c2ccn(-c3ccc(F)cc3C)n2)cn1 +CSc1ccccc1NC(=O)Cn1nc(C)c(Cl)c1C +CCC(C)N(C(=O)c1cc2ccccc2oc1=O)C(C)CC +CC(C)(C)NC(NC(=O)c1cccnc1)C(Cl)(Cl)Cl +CC(O)C1CCN(C(=O)NC2CC3CCCc4cccc2c43)C1 +Cc1cc(N)nc(-c2ccc(OC(C)C)c(C)c2)n1 +COc1cccc(CNC(=O)c2nnc(-c3ccncc3)o2)c1 +COC(=O)CSc1nc(C)nc2sc(C)c(C)c12 +OCc1nnn(-c2ccc(O)cc2)c1-c1ccncc1 +N#Cc1ccc(Cn2cnc3cc(Cl)cnc32)cc1 +CC(C)N1CC(C(=O)NCCc2nccs2)CC1=O +Cc1cc(C)c(NC(=O)c2ccc(C)nc2)c(Cl)c1 +CCc1cc2c(SCC(=O)N3CCNCC3)nc(C)nc2s1 +COCCOc1cccc(NCc2nc(C)no2)c1 +Cc1n[nH]c(C)c1S(=O)(=O)Nc1ccc(=O)n(C)c1 +COc1ccc(NC(=O)COc2cccc3[nH]ccc23)cc1 +Cc1csc(N(C)C(=O)CCCOc2ccc(F)cc2)n1 +CC(C(O)c1ccccc1)N(C)C(=O)c1ccccc1 +CC(C)(C)OC(=O)N1CCC(OCC(=O)c2cnccn2)CC1 +CC(CNC(=O)c1ccccc1SCC(N)=O)c1ccccc1 +CCn1ncc(NC(=O)C23CC4CC(C)(CC(C)(C4)C2)C3)c1C +O=C(Nc1nccs1)C(c1ccccc1)n1cnc2ccccc21 +COC(=O)c1ccc(CSc2nnc3[nH]c4ccccc4n23)o1 +Cc1ccc(S(=O)(=O)Nc2cc(C(N)=O)c(F)cc2F)cc1 +CC1CN(C(=O)c2ccc(=O)[nH]c2)CCC1(O)C1CCOCC1 +CC(C)(C)c1nnc(SCc2ccc(C#N)cc2)n(N)c1=O +CC(C)(C)OC(=O)NC1CC1(F)c1ccccc1 +COC(=O)NCC(=O)NCc1ccc(C)c(OC)c1 +Cc1cc(C(F)(F)F)n2ncc(S(=O)(=O)c3ccccc3)c2n1 +COc1cccc(C(C)NCc2ccnc(C)n2)c1 +COCc1cccc(C(=O)N(CCc2cccc(F)c2)C2CC2)c1 +CCCCc1ccc(-n2c(N)cc(=O)[nH]c2=O)cc1 +COc1ccc2c(c1)CC(C(=O)NCc1ccccc1C)CO2 +O=C(N=c1sccn1Cc1ccccc1Cl)c1ccc[nH]c1=O +CCN(CC(=O)OC)C(=O)Nc1ccc(F)cc1F +COCCN(Cc1ccccc1)C(=O)C1CCOCC1 +CC(C)(C)C(=O)NCC#CCN1CCc2ccccc2C1 +COc1ccc(OC)c(NC(=O)Cn2ccc(C)cc2=O)c1 +O=C(NCC(=O)N1CCc2ccccc2C1)c1cc2n(n1)CCCO2 +O=C(Cn1c(=O)oc2ccccc21)OCc1ccc2c(c1)OCCO2 +CC(CO)C(C)NC(=O)NCCC(=O)NC1CCCCC1 +Cc1cncc(C(=O)N2CC(c3ccccn3)C2)c1 +O=C(NCc1nncn1C1CC1)c1c(O)cc(F)cc1F +Cc1sc(=O)n(Cc2ccccc2Cl)c1C +COc1ccc(NC(=O)c2ccc[nH]2)cc1OC(F)F +Cc1ccc(-c2n[nH]cc2CNCC(O)c2ccccc2F)o1 +Cc1cc(C)c(NC(=O)c2nnc3ccccn23)c(C)c1 +CC(C)N(C(=O)CSc1nnc(NC2CC2)s1)c1ccccc1 +Cc1noc(C)c1CC(=O)Nc1cc(C(F)(F)F)ccc1F +Cc1ncc(CNC(=O)NCC(C)(C)N2CC(C)OC(C)C2)s1 +Nc1c(Nc2ccc3c(c2)OCCO3)ncnc1N1CCOCC1 +BrC1(Br)C2CCOCCC21 +Cc1cc(N2CCCCC2)nc(CNC(=O)C(C)(C)C)n1 +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1csnn1 +CC(=O)N1CCC(Nc2c(C)cc(Br)cc2C)CC1 +CC(=O)N1CCC(C(=O)Nc2nc(-c3cccnc3)cs2)CC1 +CCN1CCc2c(cc(C(C)=O)c(=O)n2C(C)C)C1 +Cc1cc(C(=O)OCc2cc(-c3ccco3)on2)no1 +O=C(NCC(O)c1ccccc1)c1ccccc1Cl +Cc1cccc(CC(C)n2cnc3c(F)cccc3c2=O)n1 +Cc1ccc(NC(=O)CN2C(=O)C(C)(C)c3ccccc32)nc1 +CC1(C)CN(C(=O)NCc2ccc(Cn3ccnc3)cc2)CCO1 +CS(=O)(=O)c1nnc(-c2cccs2)n1C1CC1 +Cc1nonc1COC(=O)c1c(C)oc(C)c1C +CN(CCc1ccc(F)cc1)C(=O)c1cnn(C(C)(C)C)c1 +CC(C)(C(=O)N1CCOC(C(N)=O)C1)c1ccccc1F +CCOc1ncccc1CNC(=O)c1cc(C)ccc1C +CC(C)(CNC(=O)Cc1ccc(-n2cnnn2)cc1)c1cccs1 +Cc1noc(CCC(=O)Oc2ccc(-c3ccccc3)cc2)n1 +COC(=O)C1=C(CN2CCOCC2)NC(=O)NC1c1ccc(F)cc1 +COC(=O)c1c(C)[nH]c(C(=O)NCC(O)c2ccco2)c1C +Cc1cc(C)cc(NC(=O)CS(=O)(=O)c2ccc(F)cc2)c1 +Cc1nc(NC(=O)c2ccc(C(F)(F)F)nc2)n(C)n1 +O=C(Nc1ccc(-n2cccn2)nc1)c1cc2cc(Cl)ccc2[nH]1 +CNC(=O)C(NC)c1ccc(Br)cc1 +COC(=O)CNc1ccc(C(=O)Nc2ccccc2OC)cc1 +CCOC(=O)CC1NCCc2ccc(NC(C)=O)cc21 +COc1ccc(Br)cc1-c1cnc[nH]1 +Cc1ccsc1CN(C(=O)c1ccc(-n2ccnc2)nn1)C(C)C +CCCOc1ccc(NC(=O)c2cccc(F)c2)c(N)c1 +CCc1ccc(S(=O)(=O)NCCC(N)=O)cc1 +CCC(NC(=O)Nc1cn(CC)nc1C)c1nc(C)c(C)s1 +CC(CC(O)c1ccco1)NC(=O)c1ccn2ccnc2c1 +CNC(=O)NCC(=O)N(Cc1ccoc1)C1CCCCC1 +NC(=O)COC(=O)CCCn1ccc2cc(Cl)ccc21 +CN(Cc1cnn(C)c1)C(=O)c1ccc2c(c1)CCC(=O)N2 +CN(Cc1ccccc1)C(=O)c1cc2ccc3cccnc3c2[nH]1 +CS(=O)(=O)N1CCCC(C(=O)Nc2ccc(-n3ccnc3)cc2)C1 +Cc1cc(C)n(CC(=O)Nc2nc3c(s2)CN(C)CC3)n1 +O=C(Cn1cnnn1)Nc1ccc(F)c(Cl)c1 +Cc1cc(C(=O)N2CC(CO)CC(CN3CCOCC3)C2)cnc1C +N#CCCN(Cc1ccco1)C(=O)Cc1cccc(O)c1 +O=C(CC1CCCCC1)Oc1cccc(N2CCCC2=O)c1 +NC(=O)C(c1ccc(Cl)cc1)N1CCN(c2ncccn2)CC1 +O=C(CCOCC(F)(F)F)NCc1ccccc1 +COCCN(Cc1ccsc1)C(=O)c1cccc(C(F)(F)F)c1 +NC(=O)c1cnc(NCCc2cccnc2)c(Cl)c1 +CC1(C)C(=O)NCCN1Cc1cc(Cl)ccc1F +CC(C)(C)C(O)CNC(=O)NCc1ccncc1 +O=S(=O)(c1cn[nH]c1)N(Cc1ccccn1)C1CC1 +O=C(Cc1c[nH]c2ccccc12)NCc1cccnc1-n1ccnc1 +CC(C)Oc1ccc(CNC(=O)Nn2cnc3ccccc32)cc1 +CCCCn1c(=O)oc(=O)c2cc(Br)ccc21 +C=CCNC(=O)c1ccc2c(c1)S(=O)(=O)N=CN2CCC +COc1ccc(NC(=O)CCc2ccco2)c(OC)c1 +CC(C)C(=O)N1CCN(C(=O)C(NC(=O)c2ccco2)C(C)C)CC1 +O=c1ccc(C(F)(F)F)cn1Cc1nnc(-c2ccccc2)o1 +COC(=O)c1ccccc1C(=O)Nc1ccnc2[nH]ncc12 +NC(=O)C(Nc1cccc(OCC(F)(F)F)c1)c1ccccc1 +O=c1[nH]cccc1-c1nc(-c2cccc(Br)c2)no1 +CCC(C)C(NC(N)=O)C(=O)N1CCNC(=O)C1 +COC1CCCCC1OC(=O)c1cnc(-c2cnn(C)c2)s1 +CCc1cc(N)c2onc(CC(=O)Nc3ccccc3)c2c1 +N#Cc1ccccc1NC(=O)C(O)c1ccc2c(c1)OCCO2 +CC(C)CNC(=O)CCc1ccc(N2CCCC2)c(N)c1 +Cc1cnc2n(c1=O)CC(C(=O)NC1CC(C)CC(C)(C)C1)CS2 +NC(=O)c1ccccc1COC(=O)c1cccc(-n2cccn2)n1 +CN(CC1CC1)C(=O)Nc1cccc(C(=O)Nc2cccc(C#N)c2)c1 +Cc1ccc(NC(=O)c2ccc(C)nc2C)c(Br)c1 +Cc1nc(C2(NC(=O)CCNC(=O)c3ccco3)CCCC2)no1 +Cn1cc(C(=O)Nc2ccc(OCCC(N)=O)cc2)c2ccccc21 +CC(C)(C)N(CC(=O)Nc1ccc(F)cc1)C(=O)Cn1ccnn1 +CC1CCC2OC3(O)C4OC(C)(C)C5C4OC23C15C +Cc1nn(CC(=O)Nc2c[nH]ccc2=O)c(=O)c2ccccc12 +CNc1nnc(-c2cnn(-c3ccc(OC)cc3)c2C)s1 +O=C(Nc1cccc(CN2CCOCC2)c1)c1cn2cccnc2n1 +Cc1ccc(N(CC(=O)N2CCCCC2)C(=O)c2cc(C)no2)cc1 +COc1ccc(Cl)cc1CNC(C(N)=O)c1ccccc1 +O=C(OC1CCCCC1)C1CCCCN1C(=O)c1cccnc1 +COc1ccc(OCC(=O)N2CCN(C)CC2c2ccccc2)cc1 +CC(C)Sc1ccccc1C(=O)N(CC(N)=O)C(C)C +CCOC(=O)c1csc(NC(=O)c2sccc2C(C)C)n1 +CCCCN(CC(N)=O)C(=O)c1cccc(Br)c1 +CC(OCC1CC1)C(=O)Nc1cc(F)ccc1Cl +CCN(C(=O)c1cc(C)oc1C)c1ccc(F)cc1 +COc1ccc(C(=O)Nc2ccc3c(c2)CCC3)cc1 +CCOC(=O)c1ccsc1NC(=O)c1c(C)nc2ccccn12 +O=c1cc(CN2CCCC2CO)[nH]c2c(F)cccc12 +O=C(NCCCOc1ccc(F)cc1)Nc1ccncc1 +CCSc1nnc(NC(=O)c2cnn(C)c2)s1 +Cc1c(C(=O)NCc2ccccc2Cl)oc2c1-c1[nH]ncc1CC2 +Cc1oc2ncnc(NCc3cc(F)cc4c3OCOC4)c2c1C +O=C(NCc1ccccc1)c1ccc2ncnc(N3CCOCC3)c2c1 +Cc1cc(NC(=O)NCC(O)c2cccc(Cl)c2)no1 +Cc1ccc(CNC(=O)c2ccc(F)cc2Br)n1C +Fc1cccc(CNCC(c2ccccc2)N2CCOCC2)c1 +CCC(C)NC(=O)Cn1nc(-c2cc(C)oc2C)cc(N)c1=O +COC(=O)c1ccn2nc(-c3ccncc3)nc2c1 +COc1ccc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2c1 +CCCc1n[nH]c(C2CN(C(=O)CC(C3CC3)C3CC3)CCO2)n1 +CC1(C)CC(C(=O)Nc2ccc(Br)cc2)CCO1 +CC(NC(=O)NCCNS(C)(=O)=O)c1ccc(F)cc1Cl +CC(NC(=O)C1CCCN1C(=O)C1CC1)c1csc2ccccc12 +CC(=O)N1CCC(C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)CC1 +Cc1cccc(Cn2cccc(C(=O)N3CCc4ccccc43)c2=O)c1 +CC(=O)Nc1cccc(C(C)OC(=O)C=C(C)C)c1 +COc1cccc(OC(=O)CCC(=O)n2nnc3cccc(C)c32)c1 +COc1ccc(CC(C)C(=O)N2CCOCC2C2CC2)cc1 +COc1nccc(-c2ccnc3[nH]ccc23)c1C#N +CCC1CN(C(=O)NCc2ccccc2OC)CCO1 +Cc1noc(NC(=O)c2ccc(Cl)cc2Cl)n1 +NC(=O)NCC(=O)NCc1cc(Br)c2c(c1)OCCO2 +CC(=O)N1CCc2cc(C(=O)NC(Cc3ccccc3)C3CC3)ccc21 +CC1CC(C)CN(S(=O)(=O)N2CCCC(C(N)=O)C2)C1 +CCCN(CC(=O)OC)C(=O)Cc1csc(C)n1 +CN1C(=O)C2=NC(=O)C(CCc3ccccc3)=NC2=NC1N +O=S(=O)(Cc1ccccc1F)c1cccs1 +CN(Cc1cc(Br)cs1)C(=O)c1ccc(F)c(F)c1 +CC(=O)Nc1ccccc1OCC(=O)NC(C)c1ccc(C)c(C)c1 +COc1ccc2cc(C(C)C(=O)N3CCNC(=O)C3)ccc2c1 +Cc1ccn(-c2ccc(NCC(=O)NCC(C)C)nn2)n1 +COc1ccc(CC(C#N)C(=O)Nc2ccccc2)cc1 +CC1CCN(c2ncnc3c2c(N)nn3CCO)CC1 +Cc1cccc(C(=O)NCC(O)(c2ccccc2)C2CC2)c1 +Cc1ccc2c(c1)N(CC(=O)NC1CC1)C(=O)CO2 +CCOC(=O)c1cnc(-n2nc(C)cc2C)nc1N1CCOCC1 +CNC(=O)C1(NC(=O)CCC2CCCO2)CCCCC1 +CC(=O)Nc1c(-c2ccc(F)cc2)csc1C#N +COCc1noc(-c2ccc(NCCc3nc(C)c(C)s3)nc2)n1 +CCn1cnnc1CNC(=O)NCc1ncc(C)c(OC)c1C +COC(=O)c1cc(NC(=O)C2COc3ccccc3O2)ccc1Cl +CCCCN(CCO)C(=O)Nc1ccc(C)cc1OC +O=C(Nc1nnc(C2CCCO2)o1)c1cccc2ccccc12 +Cc1ccc(C)c(OCC(=O)N2CCC(=O)NCC2C)c1C +COC1CCCN(C(=O)CCc2ncc(-c3ccc(Cl)cc3)o2)C1 +Clc1cc(Cl)cc(NCc2nc(C3CC3)no2)c1 +CC(=O)Nc1ccc(C(=O)Nc2cccc3ncccc23)cc1 +CCCc1cc(=O)n2c(n1)SCC2CC(=O)NCc1cccs1 +CNc1nnc(SCc2cc(-c3ccc(OC)cc3)no2)s1 +O=C(CNC(=O)c1cc2ccoc2cn1)NCC1CCCCC1 +CCCc1c(NC(=O)c2ccccc2OCC)c(C(N)=O)nn1C +CCCc1nnc2sc(-c3ccc(F)cc3)nn12 +CN(C)Cc1c(O)c(=O)cc(CO)n1CC1CCCO1 +Cc1cccc(C(C)N2CCn3c(nn(C)c3=O)C2)c1 +OCCOc1ccc(CN2CCN(c3ncccn3)CC2)cc1 +CCN(CC)C(=O)N1CCC(C(=O)NCCCn2cccn2)CC1 +CCN1CC2(CCN(C(=O)c3c[nH]c(=O)c(Cl)c3)CC2)CC1=O +CC(=O)Nc1cc(NC(=O)NC(C)c2ccc(C#N)cc2)ccc1F +COc1ccccc1CCn1ccnc1SCC#N +Cn1cnc2c1C(COCC1CCOCC1)CN(C1CCOCC1)C2 +CNc1nc(C)c(C(=O)N2CCCC(OCc3cccnc3)C2)s1 +O=C(CN1CCN(C(=O)NCc2ccccc2F)CC1)N1CCCC1 +COc1cccc(C(=O)Nc2cc(=O)n(C)c(=O)n2C)c1 +CC(C)C(=O)Nc1ccc(OCC(=O)NCc2ccccc2F)cc1 +CCn1cc(NC(=O)NCc2ccc(CO)c(F)c2)cn1 +CC(=O)NCCn1nc(C(F)(F)F)cc1C1CC1 +COc1cccc(N2CCCC(NC(=O)C3CC3C)C2)c1 +CC(C)c1nc(Cn2ccnc2-c2ccncc2)no1 +CCC(=O)c1c[nH]c(C(=O)Nc2ccc(OC)cc2)c1 +COC(=O)CCC(=O)NC(C)C(=O)NC1CCCC1 +CC(=O)Nc1ccc2c(c1)N(C(=O)c1cccnc1)CCC2 +Cn1nc(NC(=O)Cn2cnnn2)c2c(N3CCOC3=O)cccc21 +CC(C)CNC(=O)C1CCCN(c2ccc3nnnn3n2)C1 +CCN(CC)S(=O)(=O)N1CCN(CC(F)(F)C(F)F)CC1 +COC(=O)c1nnc2c(-c3ccccc3)cnn2c1C +CC(C)c1cccc(OCC(=O)Nn2cnc3ccccc3c2=O)c1 +CSc1cccc(OC2CC2)c1S(N)(=O)=O +CC1CC(C)CN(C(=O)c2ccc(S(=O)C(C)C)cc2)C1 +NC(=O)Nc1ccc(CNS(=O)(=O)c2ccc(F)cc2F)cc1 +CC(C)N(Cc1ccccc1)C(=O)NCc1ncn(C)n1 +O=C(CCCc1cc(F)ccc1F)NC1CCC(O)CC1 +O=c1cc(CNc2ccc(SC(F)F)cc2)nc2sccn12 +CCCCN1C(=O)CC(C(N)=O)C1c1ccc(OC)cc1 +Cc1cnccc1NC(=O)C1COc2ccc(F)cc2C1 +CC1CC(C)CN(C(=O)CSc2nc(=O)ccn2C(C)C)C1 +Cc1nc2c(NC(=O)c3cccs3)cccn2n1 +O=c1cc(-c2ccccc2)[nH]c2ccc(Cl)cc12 +N#Cc1ccc(NC(=O)CNC(=O)c2cc3ccccn3n2)cc1 +CCOc1ccccc1CNC(=O)Nc1ccc(F)cc1F +COc1ccccc1NC(=O)N1CCc2c(ncnc2OC)C1 +O=C(c1ccncc1)c1cccc(C2OCCCO2)c1 +CCc1ccc(CNC(=O)c2cc(-c3csc(C)n3)c[nH]2)s1 +CCn1nc(C)c(C(C)NC(=O)Nc2c(OC)nn(C)c2C)c1C +CC(C)C(C)N(C1CC1)S(=O)(=O)c1cnn(C)c1 +COc1cccc(C(=O)NCCc2nc3c(s2)CCCC3)c1OC +COc1ccc(C(=O)Nc2ccc(-n3cnnn3)c(C)c2)cc1 +COc1ccccc1S(=O)(=O)Cc1cc(-c2ccccc2)on1 +CCN(C)C(=O)CCc1ncc(-c2ccc(Cl)cc2)o1 +COc1ccc2c(C(=O)N3CCC(C)CC3)cc(=O)oc2c1 +COc1ccc(S(=O)(=O)NCC(O)c2ccc(C)o2)cc1C +Cc1nc(C(=O)N(C)Cc2cc(-c3cccs3)n[nH]2)cs1 +CC(=O)c1sc(CNc2c(C)cccc2C(C)C)nc1C +CC(=O)Nc1ccc(C(F)(F)F)cc1NC1CCN(C2CC2)C1=O +CN(C)S(=O)(=O)NC(=O)Cc1cn(C)c2ccccc12 +COCCN1CC2CN(C3CCOCC3)CCN2C1=O +O=C(CC1Oc2ccccc2NC1=O)NCCc1ccco1 +Cc1cc(NCc2cc(C(C)(C)C)n[nH]2)n2nc(C)cc2n1 +Nc1cc2c(cc1NC(=O)c1ccncc1)OCCO2 +COc1ccccc1-c1nnc(SC(C)C)n1C +COC(=O)CCCN(C)S(=O)(=O)c1c(C)cc(C)cc1C +CCCCCc1ccc(NC(=O)N2CCOC(C(N)=O)C2)cc1 +CC(C)(C)NC(=O)Cc1csc(NC(=O)c2ccccc2)n1 +Cc1[nH]n(-c2ccccc2)c(=O)c1Sc1n[nH]c(=O)[nH]c1=O +Cc1ccc(O)c(C(=O)NCCNC(=O)c2cccnc2)c1 +CC(=O)NC(CC(=O)Nc1cccc(C(C)=O)c1)c1ccc(C)cc1 +CN(Cc1cccc(C#N)c1)C(=O)NCc1ccnc(-n2cccn2)c1 +CCOC(=O)CNS(=O)(=O)c1c(C)cc(C)cc1C +CCC(NC(=O)CCC(=O)c1ccccc1)c1ccc(C)cc1 +Cc1nc(NC(=O)c2ccc(Cl)cc2)sc1C +CC(C)n1cc(CCC(=O)NCc2cccn2C)c2ccccc21 +CCc1sc(C(=O)NCCN2CCOCC2)cc1Br +CCN(Cc1cccc(F)c1)C(=O)Cc1csc(C)n1 +COC(=O)C(C)CN1CCc2cc(C(C)=O)ccc21 +CC1CCC(C(N)=O)CN1S(=O)(=O)c1cnn(-c2ccccc2)c1 +Cc1cnc2c(c1)N(S(=O)(=O)c1ccc(F)c(C)c1)CCO2 +O=C(Nn1cnc2ccccc2c1=O)c1ccc(-c2cscn2)cc1 +CCc1noc(C2CCCN(C(=O)c3cc(C)oc3C)C2)n1 +CCc1nn(C)c(CC)c1CNC(=O)NCCc1csc(C)n1 +C=CCN(c1ccc(C(N)=O)cc1)S(C)(=O)=O +O=c1[nH]nc(CCc2ccccc2O)n1-c1ccccc1Cl +N#Cc1ccc(NC(=O)NCc2cscn2)cc1 +O=C(Cn1ncc2ccccc2c1=O)N1CCCc2ccccc21 +Cc1cccc(CCC(=O)OCC(=O)NC(C)C)c1 +Cc1nc(-c2ccc(NC(=O)c3nccnc3N)cc2)co1 +Cc1sc2nc(SC3CCOC3=O)n(C(C)C)c(=O)c2c1C +CS(=O)(=O)c1ccc(NC(=O)c2cccnc2)cc1C#N +Nc1nccnc1C(=O)NCc1ccc(N2CCCCC2=O)cc1 +CN(C)c1cccc(C(=O)N2CCC(n3cnc4ccccc43)CC2)c1 +O=C(CSc1ncc2ccccn12)c1ccccc1 +CCCNc1ncnc(Nc2ccc3c(c2)OCCO3)c1N +CC(Oc1ccc2ccc(=O)oc2c1)C(=O)N1CCOCC1 +CCn1cc(NC(=O)NCC2(c3ccccc3)CCC2)cn1 +Cc1[nH]ncc1S(=O)(=O)NCC1COCCO1 +CCOc1cc(Br)c(CCO)cc1OCC +C#CCOCC1CCCN(C(=O)c2cccc(Br)c2)C1 +CCC1CCCC(NC(=O)N2CCN(Cc3cccnc3)CC2)C1 +CCCNc1cc(C(=O)Nc2cc(C)no2)ccn1 +CN(C)S(=O)(=O)N1CCCC1c1ccccc1C(F)(F)F +Cc1cc(NC(=O)Cc2c(C)nn(CC(C)C)c2C)ccn1 +CCOC1CCN(c2ncnc3c2Cc2ccccc2OC3)CC1 +Cc1ncnc(N)c1-c1ccc(Cl)cc1Cl +COCCn1nc(C(=O)Nc2ccc(N(C)C)nc2)ccc1=O +CCOC(=O)CC(C)CNC(=O)N1CCC(c2nc[nH]n2)CC1 +CCOc1cccc(COC(=O)c2cnn(-c3ccncc3)c2C)n1 +Cc1nnsc1C(=O)N1CCC(CNC(=O)C(C)C)CC1 +CCOc1ccccc1NS(=O)(=O)c1ccc2oc(=O)ccc2c1 +CC(=O)Nc1nc2ccc(NC(=O)c3ccccn3)cc2s1 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccco2)c(C)c1 +COCCNC(=O)CNC(=O)c1ccc(C)cc1C +Cc1ccc(N2CCCN(Cc3cc(-c4ccccc4)[nH]n3)CC2)nn1 +CCc1nnc(-c2cc(S(=O)(=O)NCc3cccs3)c[nH]2)o1 +CCOc1ccc(F)cc1C1CCN(C(=O)OC(C)(C)C)CC1=O +C(=Cc1ccnnc1)c1ccc(Oc2cnccn2)cc1 +O=C(Nc1ccccc1OC(F)F)N1CCC(n2cccc2)CC1 +C=CCN(CC=C)C(=O)Cn1ccc2ccc(OC)cc2c1=O +CCC(C)N(Cc1ccccc1)S(=O)(=O)c1cn[nH]c1 +Cc1nc(C)n(Cc2nc(-c3cccc(Cl)c3)oc2C)n1 +CCOc1cccc(NC(=O)NC(C)(C)CCO)c1 +CC(=O)Nc1ccc(O)c(C(=O)NCCc2ccc(O)cc2)c1 +CCc1cc(N2CCCC(C(=O)NC)C2)nc(-c2ccccn2)n1 +COc1ccc(CNC(=O)Cn2ccc(C(F)(F)F)n2)cc1 +CCN(CC)C(=O)Nc1ccc(C)cc1OCC1CCCO1 +Cc1ccc(OC(C)C(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1 +CCN(CC)C(=O)c1cccc(NC(=O)CCc2c(C)n[nH]c2C)c1 +Cc1cc(C(=O)NCC(O)c2cccc(OC(C)C)c2)on1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)NCC1CCCO1 +COCCn1cc(NC(=O)N2CCN(C(=O)c3ccoc3)CC2)cn1 +COc1cccc2c1cc(C(=O)NCc1ccc(F)cc1)n2C +COC(=O)CCC(=O)c1ccc(C(F)(F)F)cc1OC +CCN(Cc1cccs1)C(=O)c1ccc2c(c1)OCO2 +CNS(=O)(=O)c1ccc(NC(=O)Cc2ccccc2C)cc1 +CC1CCCCN1C(=O)COC(=O)Cc1c[nH]c2ccccc12 +Cn1ccn2ncc(C(=O)N3Cc4cnc(C(C)(C)C)nc4C3)c12 +Cc1ccc(C(C)NS(=O)(=O)c2ccc3c(c2)CCO3)cc1 +CC(=O)NCCNC(=O)c1sc(-c2cccc(Cl)c2)nc1C +Cc1csc(-n2nnc(CO)c2Cc2ccc(F)cc2)n1 +CCCN1C(=O)NC(c2cccc(C#N)c2)C(C(=O)OC)=C1C +COc1ccc(C)cc1NC(=O)NCCCn1cnc2ccccc21 +COC(=O)c1ccc(NCc2ccc(F)cc2)c(N)c1 +Cc1ccc(C(=O)NC2C3CCOC3C2(C)C)cn1 +Cc1c(C(=O)N2CCC2)sc2nc3n(c(=O)c12)CCCCC3 +CC(=O)Nc1ccc(NC(=O)COc2cccc(N)c2)cc1 +COCCCN(C)C(=O)c1cc(NC(C)=O)ccc1O +CCC(C)(C)NC(=O)COc1ccc(F)cc1F +O=C(Cc1ccc2c(c1)OCO2)N1CCOC(c2ccc(F)cc2)C1 +N#Cc1ccc(N2CCC(C(=O)Nc3ccc(F)cc3)CC2)nc1 +CCc1ccc(-c2csc(CCN3CCOC3=O)n2)cc1 +O=S(=O)(c1ccc(Cl)cc1)N(CCO)C1CC1 +COc1ccc(C(=O)N(C)C(C)c2cccnc2)c(OC)c1OC +CCOC(=O)c1nc(C)sc1-c1cc(OC)c(OC)c(OC)c1 +Cc1cc(C(=O)NC(C)c2c(Cl)ccc(F)c2Cl)n(C)n1 +COc1ccc(C(=O)NCCc2ccccc2Cl)cn1 +Cc1csc(C2(NC(=O)Cn3ncc4ccccc43)CCCC2)n1 +C=CCN(CC=C)C(=O)c1ccc(NC(=O)c2cc[nH]n2)cc1 +Cn1nc(C(C)(C)C)cc1C(=O)OCC(F)(F)F +CCc1noc(CNc2cccc(C(=O)OC)c2)n1 +Brc1cccc(CNc2ccon2)c1 +CC(C)c1ccccc1NC(=O)c1ccc(N)cc1Cl +O=C(c1ccc(=O)n(-c2ccccc2)n1)N(CC(F)F)C1CC1 +C#CCN1CCN(C(=O)NC2C3CCOC3C23CCC3)CC1 +Cc1ccc(C(=O)N2CCN(Cc3cc(C)no3)CC2)cn1 +CCOC(=O)CCC(=O)Nc1ccc2c(C)cc(=O)[nH]c2c1 +O=C(CCn1ccccc1=O)Nc1ccccc1Cl +N#Cc1cc(C#N)c(SCC(=O)NCC(F)(F)F)nc1N +Nc1cc(C(=O)CNc2ccccc2Cl)ccc1F +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2ccnc(C)c2)c1C +CC(C)(C)NC(=O)NC1CCN(C(=O)c2ccn3ccsc23)C1 +CC(C)c1nccc(OC2CC2)c1Br +N#CCCN1CCN(C(=O)c2cccc(F)c2)CC1 +CC(C)(C)C(=O)c1nccn1-c1cccc(C#N)c1 +C=CCn1c(C)nnc1SC(C)C(=O)c1ccc(C)cc1 +CCOC(=O)C1=C(C)C(C(=O)Nc2cccnc2)=NC1C +CC(C)CCC(=O)N1CCN(Cc2c[nH]nc2-c2cccnc2)CC1 +CC(CNC(=O)NC(C)C(C)CO)c1nc(-c2ccccc2)no1 +Cc1nncn1CCNC(=O)COc1cc(Cl)cc(Cl)c1 +COc1ccc(-n2nnnc2SCc2nc(C)cc(=O)[nH]2)cc1 +CCc1ccccc1NC(=O)Cn1cnc(-c2ccccc2)cc1=O +N#CCc1nc(-c2cc3cc(Cl)ccc3oc2=O)cs1 +CCCC(NCc1ccc(F)cc1F)C(=O)OC +O=C(NCc1cn(-c2ccccc2)nn1)Nc1ccc(F)cc1Cl +CN1CC(Cc2ccc(F)cc2)Oc2cc(O)ccc21 +COCCNS(=O)(=O)c1ccc(C(=O)Nc2ccc(C)cn2)cc1 +C=CCn1c(C)nnc1SC(C(=O)N1CCOCC1)C(C)C +COC1CCCN(C(=O)c2ccc(CNC(=O)C(C)C)cc2)C1 +Cc1nn(Cc2ccc(F)cc2)c(C)c1Br +CC(C)c1csc2nc(-c3cccnc3)c(N)n12 +CC(C)OC(=O)CS(=O)(=O)c1ccc(C(=O)C(C)C)cc1 +Cn1ccnc1SCC(=O)Nc1ccc(S(N)(=O)=O)cc1 +COC(=O)c1cccc(NCC(=O)N(C)C)c1C +O=C(CCc1cccc(F)c1)Nc1ccc(-n2cncn2)nc1 +CC1CN(c2cc(Cl)cc(Cl)c2)CCC1=O +CCCC1CN(C(=O)c2ccc(S(=O)(=O)NC)cc2)CCO1 +CCc1cccc(C)c1NC(=O)CNc1cccc(C(=O)OC)c1 +COC(=O)C1CCN(C(=O)Nc2ccc(Cl)cc2)CC1 +Cn1c(SCCCOc2ccc(F)cc2)nnc1-c1ccncc1 +CCOC(=O)C1CCCN(C(=O)c2[nH]nc(C3CC3)c2Cl)C1 +Cc1ccc(CNC(=O)NCc2cn(-c3ccccc3)nn2)cc1 +CCNS(=O)(=O)c1cc(C(C)=O)ccc1Cl +Cc1nc(CCC(=O)N2CCN(c3ccc(F)cc3)CC2)cs1 +CCc1c(C)nc2n(c1=O)C(CC(=O)NCC(C)C)CS2 +CCOc1cc(C)c(-c2nc(C)cc(N)n2)cc1C +CN(C)c1ncc(C(=O)NCc2ccccc2Cl)cn1 +CCC(CO)NS(=O)(=O)c1c(N)ccc(C)c1C +CCc1cnc(CCNC(=O)c2cnc3ccc(C)cn23)s1 +N#CCCN(CCc1ccccc1)C(=O)c1ccccc1Cl +CC(C)Oc1nc(-c2ccncc2)nc2ccccc12 +CC(=O)NCCCCCC(=O)Nc1ccc(Cl)cc1F +O=C(NCc1cscn1)c1ccc(Cn2ccccc2=O)o1 +CCCS(=O)(=O)c1ccc2[nH]c(=NC(=O)OC)[nH]c2c1 +CC(=O)N(C)c1cccc(NC(=O)COc2ccccc2C(C)C)c1 +COc1ccc(CSc2nc(N)cc(N)n2)cc1F +CC1CN(C(=O)CCc2nc(-c3cccnc3)no2)c2ccccc21 +O=C(Cc1cccnc1)Nc1ccccc1N1CCC(CO)CC1 +Nc1cc(=O)[nH]c(=O)n1-c1ccc(F)c(Cl)c1 +CCC1CCCCN1C(=O)NC(C)C(=O)N1CCCCC1 +CCc1cccc(N2CCC(NC(=O)C3CC3)CC2)c1 +COc1ccc(O)c(C(=O)Nc2ncc(C)s2)c1 +NC(=O)OCCNC(=O)C1CC1c1ccccc1F +Cc1cccc(C)c1Oc1ncccc1CNC(=O)C1(C#N)CC1 +Cc1csc(C(C)NC(=O)Nc2ccc(-n3cccn3)nc2)n1 +CCn1cc(NC(=O)NCc2ccc(S(N)(=O)=O)cc2)cn1 +O=C(NCc1ccc(Br)cc1)c1ccsc1 +O=C(CCc1ccc2ccccc2c1)Nc1cc[nH]n1 +COCc1cccc(C(=O)OCCc2cccnc2)c1 +CC(=O)N1CCC2(CC1)CN(C(C)=O)Cc1cc(F)ccc12 +Fc1ccc(CNc2cc(Cl)ccn2)cc1F +O=C(Nc1cccc(CO)c1)C1Cc2ccccc2S1 +O=C(CSc1ccccn1)N1CCCC1c1ccc(F)cc1 +O=C(CNc1cc(F)ccc1Br)NCC(F)(F)F +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(OC(F)F)c(F)c2)c1C +CC1CCc2sc3ncnc(NCCCN4CCOCC4)c3c2C1 +COc1ccccc1SCc1nc(N)nc(N)n1 +CC(CC#N)N(C)C(=O)Nc1cccc(SC(F)F)c1 +C=CCOCC1CN(C(=O)Cc2ccsc2)Cc2ccnn2C1 +CN(C)C(=O)c1ccc(NC(=O)CN(C)c2ccc(F)c(F)c2)cc1 +NC(=O)c1ccccc1COC(=O)c1ccc2ccccc2n1 +CCOc1ccc(CNC(=O)c2ccc3c(c2)OCO3)cc1 +Brc1cccc(-c2noc3occc23)c1 +CCCN(Cc1cc(-c2ccco2)on1)C(=O)c1ccco1 +COc1ccc(CN(C)C(=O)Cn2cccnc2=O)cc1F +CS(=O)c1nncn1Cc1cc(Br)ccc1F +Cc1nc2cc(NC(=O)Cn3cnnn3)ccc2o1 +Cc1ccc(C)c(NC(=O)C(O)c2ccc(Cl)cc2)c1 +Cc1ccsc1C(=O)NCCS(=O)(=O)N1CC(C)OC(C)C1 +COCCC1COC2(CCN(C(=O)c3cccs3)C2)C1 +CCN(CC)C(=O)CNc1ccccc1C(=O)N(C)C1CCCCC1 +CC1(Cn2ccnc2-c2ccc(-c3cc[nH]n3)o2)CCCO1 +Cc1cccc(C)c1NC(=O)COn1nnc2ccccc21 +Cc1ccc(C(=O)NCC(F)(F)F)cc1NC(=O)Cc1ccc[nH]1 +Cc1c(C(=O)N(C)CC(F)F)nnn1-c1ccc(OC(C)C)cc1 +COc1cccc(C(=O)N2CC(c3nc(-c4ccncc4)no3)C2)c1 +O=C(Nc1cccc(-c2cn[nH]c2)c1)c1ccc(N2CCOC2=O)cc1 +O=C(N=c1[nH]ncn1-c1ccccc1)c1c(F)c(F)cc(F)c1F +O=C(NCCC(=O)N1CCCCC1)c1cccc(Cl)c1 +Cc1cc(C(=O)N(C)Cc2c(F)cccc2Cl)on1 +CC(COc1ccccc1)NC(=O)c1ccsc1 +CCOC(CC)C(=O)Nc1cc(OC)c(OC)cc1Br +CCn1nccc1CN(C)S(=O)(=O)c1cn(C(F)F)nc1C +CC(C)N(Cc1ccc(C#N)cc1)C(=O)CCC(=O)c1cccs1 +Cc1cccc(C(C)(C)NC(=O)NC(C)C2CCCO2)c1 +CC(C)C(C#N)NS(=O)(=O)Cc1ccccc1Cl +CCN(Cc1ccc(OC)cc1)Cc1cc(=O)c2cc(C)ccc2[nH]1 +CCn1nc(CC(C)C)cc1C(=O)NCCc1ccc(O)cc1 +CCCCS(=O)(=O)NCC(=O)N1CCC(C)CC1c1ccco1 +Cc1cccc(N2CC(C(=O)Nc3ccc4c(c3)OCO4)CC2=O)c1 +COCCNC(=O)c1cc(Cl)ccc1OC(C)C +CC(C)c1ccc(CN(C)C(=O)CCC(=O)Nc2nccs2)cc1 +COCCCNC(=O)CC1c2ccccc2CCN1C +O=C(CSc1ccc(O)cc1)Nc1ccc(F)cc1 +CCOc1ccc(N(CCC#N)C(=O)Cc2ccc[nH]2)cc1 +NC(=O)CN1CCN(C(=O)C2C3CC4CC(C3)CC2C4)CC1 +CC(C)(C)n1cc(C(=O)NCc2ccnc(OC3CCCC3)c2)cn1 +CC(C)CCNC(=O)c1[nH]cnc1C(=O)NC1CCCCC1 +COc1c(C)cnc(CNC(=O)c2ccc(-n3ccnn3)cc2)c1C +CCc1noc(CC)c1CNC(=O)N1CCCC(CC(N)=O)C1 +Cc1c(-c2ccc(F)c(F)c2)[nH]c2nc3cc(N)ccc3n12 +CCOc1ccc(N2CCN(CC(=O)NC(C)(C)CO)C2=O)cc1 +CCOC(=O)Cc1cc(C(=O)c2cccc(F)c2)c(N)o1 +Nc1cc(NC(=O)c2cccs2)c(F)cc1F +CSc1ccc(CCNC(=O)CCn2cccn2)cc1 +COc1ccc(CCC(=O)Nc2cc(S(C)(=O)=O)ccc2C)cc1 +CCCCN(CC)C(=O)c1ccc(NC(=O)CC)cc1 +CC(C)c1ccc(S(=O)(=O)N2CCN(c3ccccn3)CC2)cc1 +CC(C)(C)c1nnc(SCc2noc(-c3ccccc3)n2)n1N +CC(c1cccs1)N(C)Cc1nnc(-c2ccc(F)cc2)o1 +CCc1n[nH]c(SCC(=O)N2CCC3(CC2)NCCNC3=O)n1 +Cc1cc(=O)oc(C)c1C(=O)Nc1cc(Cl)ccc1F +Cn1ccsc1=NC(=O)Cn1c(=O)[nH]c2ccccc21 +COC(=O)CCn1c(=O)[nH]c2cc(C(=O)OC)ccc21 +Cc1cc(C(=O)Nc2nccs2)nn1C(C)(C)C +CCC1(C)Nc2ccccc2C(=O)N1Cc1ccccc1 +Cn1cc(S(=O)(=O)Oc2ccccc2Cl)c(=O)n(C)c1=O +COC(=O)Cc1csc(NC(=O)c2cccc3ccccc23)n1 +COc1ccc(C(=O)CN2CCN(C(=O)OC(C)(C)C)CC2)cc1 +c1ccc(C2(c3nc(-c4ccc(-n5cccn5)nc4)no3)CC2)cc1 +Cc1ccc(C)c(C(O)CCC(=O)NCc2ccccc2)c1 +CC(C)(C)n1nccc1C(=O)NCc1ccccc1 +O=C(NCc1ccc(Cl)cc1)c1ccc(CO)cc1 +COc1ccc(C(=O)N2CCC(c3n[nH]c(C4CC4)n3)CC2)c(C)c1 +Cc1occc1C(=O)Nc1ccn(Cc2ccccc2F)n1 +Cn1c(C(F)(F)F)nc2cc(F)c(F)c(F)c21 +Nc1ccccc1-c1nnc(N2CCOCC2)s1 +CCOC1CC(Nc2cnn(C)c(=O)c2Br)C12CCC2 +O=C(NC1CC1)c1cccc2c1-c1ccccc1C2=O +CC(=O)Nc1ccc(S(=O)(=O)NC(C)CO)c(F)c1 +O=C(NCC1CC1)NC1CCc2cc(Cl)ccc21 +COc1ccc(CCC(=O)N(C(C)C)C2CCOCC2)cc1OC +O=C(NCCCOc1ccc(Cl)cc1Cl)NC1CC1 +COc1ccc(NC(=O)c2ocnc2C)c(OC)c1 +CCn1ncc(C(=O)NCC(C)(C)c2ccncc2)c1C(F)(F)F +NC(=O)c1ccc(C(=O)NCc2ccc(F)cc2)nc1 +CNC(=O)c1cccc(NC(C)C(=O)N(C(C)C)C(C)C)c1 +Cn1nnnc1SCC(=O)NCCc1c[nH]c2ccccc12 +CCCCCCNC(=O)c1cc2c(C)nn(C)c2nc1N +CN1CCN(C(=O)c2ccc(Br)cc2)c2cccnc21 +Cc1cccc(N2CCN(C(=O)c3cnc4ccccn4c3=O)CC2)c1 +O=S(=O)(NCCc1nncn1C1CC1)c1ccc(Cl)cc1F +CC(C)NC(=O)C1CN(C(=O)c2ccoc2)CC12CCOCC2 +Cc1cc(NC(=O)CCN2CCOC(Cn3cccn3)C2)no1 +CCOC(=O)C1(NC(=O)c2csc(C)n2)CCCCC1 +Cc1noc(C)c1CCCNC(=O)NCCc1cccnc1 +Nc1ccc(F)c(NC(=O)CCOC2CCCCC2)c1 +Nc1nc2c(c(C(F)(F)F)n1)CC(=O)N2C1CCCC1 +CCOc1cccc(Cc2nc(C)c(N)c(C)n2)c1 +NC(=O)c1cnn2ccn(C3OC(CO)C(O)C3O)c12 +O=C(C(C1CC1)C1CC1)N1CCC(n2ccnn2)CC1 +CC(Nc1ccc(=O)n(C)c1)c1cc(F)ccc1F +CCCn1nnnc1COC(=O)C(C)N1CCc2ccccc2C1 +C#Cc1cccc(NC(=O)c2ccc(Br)cc2)c1 +CC(=O)NCCc1ccc(-c2csc(-c3ccccn3)n2)cc1 +O=C1CCc2cc(OCCNC(=O)C(O)c3ccccc3)ccc2N1 +Cc1cnc2c(c1)nc(-c1cccs1)n2CCC#N +Cn1c(=O)c2sccc2n(CC(=O)NCC2CCCO2)c1=O +CC(C)Cn1cnnc1C1CCCN1Cc1cccnc1 +Cc1cc(C)cc(NC(=O)c2cnn(-c3ccccc3)c2)c1 +COc1ccc(-c2nc(-c3ccc(O)cc3)no2)cc1 +O=C(C1CC1c1ccco1)N1CCCCCC1c1ccncc1 +Nn1c(SCC(=O)NC2CC2)nnc1-c1ccncc1 +O=C(Nc1ccccc1)C1CCCN(c2cncc(-n3cccn3)n2)C1 +CC(O)(CNS(=O)(=O)c1ccc(C(F)(F)F)cc1)C1CC1 +CN(C(=O)CCCC(O)c1ccc(F)cc1)c1ccccc1 +Cc1ccnc(SCC2CCN(C(=O)OC(C)(C)C)C2)n1 +CCN(C(=O)c1ccncc1F)c1ccc(C)cc1C +O=C(CSc1ccc(C(=O)C2CC2)cc1)Nc1nccs1 +COC(=O)CN1CCc2c(N)cc(OC)c(OC)c2C1 +Cc1ccc(C)c(OCCN(C)C(=O)CCc2cn[nH]c2)c1 +CCc1ccc(C2COCCN2Cc2cc(C)oc2C)o1 +CC(=O)Nc1ccc(OCC(=O)Nc2ccc(C)c(C)c2)cc1 +COC(=O)N1CCCC(C(=O)N2CCC(c3ccc(OC)cc3)C2)C1 +O=C(OCCOc1ccccc1)c1cn(-c2ccccc2)nn1 +O=C(Cc1cn2ccsc2n1)N1CCc2cc(F)ccc2C1 +CC(=O)c1c(C)[nH]c(C(=O)NCC(=O)NC(C)C)c1C +CC(=O)Nc1cc(S(=O)(=O)N(CC(C)C)CC(C)C)ccc1C +Cc1ccc(-c2nnc(C(C)Sc3nc(N)cc(=O)[nH]3)o2)cc1 +CC(=O)N1CCC(Cc2cnc(Nc3ncccn3)cn2)CC1 +Cc1[nH]ccc1C(=O)Nc1ccc(F)cc1NC1CC1 +COc1cc(S(=O)(=O)NC2CCCCC2)c(OC)cc1C +CCN(C(=O)c1cccc(Br)c1)C(C)COC +CC(C)(C)c1cnc(CSc2nncn2CCc2ccccn2)o1 +O=C(CC1OC(CNC(=O)C2CCCC2)C(O)C1O)NC1CC1 +Cc1nc(-c2ccsc2)ccc1C(=O)NCC(F)(F)F +O=C(NCc1cccc(C(F)(F)F)c1)c1ccncc1 +Cc1cc(C(=O)CN2CCOC(C(N)=O)C2)c(C)n1C1CC1 +Cc1cnc(C2NCCc3c(F)cc(F)cc32)cn1 +CCCNC(=O)c1ccc(Br)cc1O +O=C(NCCc1ccc2c(c1)OCO2)C1CC2CCC1C2 +COc1ccc(C(=O)Nc2nnc(-c3cc(C)nn3C)o2)cc1OC +CCS(=O)(=O)N1CCc2cc(C(=O)NC)c(N(C)C)nc2CC1 +Cc1cccc(-c2nc(CSc3nnnn3C3CCCC3)no2)c1 +NC(=O)C1(N2CCN(C(=O)c3ccc(Cl)cc3)CC2)CCCCC1 +Cn1cc(C2CC3(CCN(C(=O)c4ccco4)CC3)NC2=O)cn1 +CC(C)Oc1nnc(SCC(=O)Nc2sccc2C#N)s1 +N#Cc1cccnc1N1CCCN(C(=O)c2ccsc2)CC1 +O=C(c1ccccn1)N(Cc1ccsc1)Cc1ccco1 +O=C(Cn1cccc(C(F)(F)F)c1=O)OCC1CC=CCC1 +CCN(CC(=O)NC(C)C)C(=O)COc1ccccc1 +COC(=O)Cn1c(SCc2ccccc2)nc2ccccc2c1=O +CCOC(=O)CC1=Nn2c(nnc2-c2ccccc2Cl)SC1 +Cc1cc(C2CCCN(Cc3ccncc3)C2)ccn1 +CCc1ccccc1NC(=O)CC(C#N)c1ccco1 +O=C1CCCN1c1ccc(CC(=O)N2CCOC3CCCCC32)cc1 +CSc1nc(=O)c2c(n1C)NC(=O)CC2c1ccc(Cl)cc1 +Cc1nccn1-c1ccc(CNC(=O)C2CC2C)cc1F +COc1ccnc(N2CCN(C(=O)c3nccc4ccccc34)CC2)n1 +C=CCN(Cc1ccccc1)C(=O)CNC(=O)c1ccoc1 +CC(C)CCC(NS(N)(=O)=O)c1ccc(Cl)cc1 +CCOc1ccccc1CNC(=O)C1CCN(C(=O)C(C)C)CC1 +Cn1nc(C(=O)N2CCC(Oc3ncccn3)CC2)ccc1=O +CC1(CNC(=O)CCc2ccc(-c3ccccc3)o2)CC1 +COC(=O)C(O)(CC(=O)Nc1cccc2ccccc12)C(F)(F)F +Cn1cc(Nc2cccc(C(=O)Nc3cc(C#N)ccc3O)c2)cn1 +Cc1cc(C)c(O)c(C(=O)NCc2csc(=O)[nH]2)c1 +COC(=O)C1CCn2nc(-c3ccccc3)nc2C1 +CNc1snc(C)c1C(=O)N(C)Cc1cccc(F)c1 +CC(=O)c1cccc(NC(=O)CCN2C(=O)CCc3ccccc32)c1 +CC(C)C(NC(=O)c1ccco1)C(=O)Nc1cc(F)cc(F)c1 +NC(=O)c1ccc(C(=O)Nc2ccc(SC3CCCC3)cc2)cc1 +CCOc1ccc(NC(=O)C2CCOC2)cc1Cl +CCOC1CCCN(C(=O)c2ccc(=O)n(Cc3ccccc3)n2)C1 +N#CC(CC(=O)NCc1ccccc1)c1ccc(F)cc1 +CNC(=O)COC(=O)c1ccccc1NC(=O)c1ccco1 +Cc1ncc(-c2ccc(NC(=O)Cc3c[nH]c4ccccc34)cc2)o1 +CC(NC(=O)Nc1ccccc1)C(=O)N1CCCC(C(N)=O)C1 +Cc1ccsc1Cn1nccc1NC(=O)c1cccc(C#N)c1 +COc1ccsc1C(=O)N1c2ccccc2OCC1C +COC(=O)CNc1ccc2nc(C(C)C)sc2c1 +CC1=CC(C)=NC1C(=O)N1CCCC(C(=O)c2cccc(Cl)c2)C1 +COc1cccc(CNC(=O)c2cn(-c3cccc(F)c3)nn2)c1 +CCC(C)NC(=O)NCc1ccc(CN2CC(C)OC(C)C2)cc1 +CCOc1nn(CC)cc1C(=O)Nc1cc(OC)ccc1OC +Cc1cnc(C(=O)OCC(=O)N(Cc2ccccc2)C(C)C)cn1 +CC(C)C(NC(=O)Cn1ccc(C(F)(F)F)n1)c1cccs1 +Cc1ccc(C2CSc3nnc(C(F)(F)F)n3N2)cc1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(Cl)cc2)cc1 +COC(=O)c1cccc(Cn2c(CO)nc3ccccc32)c1 +Cc1csc(CCCNC(=O)N2CCCC(CC(N)=O)C2)n1 +CCCCNC(=O)CN1C(=O)CCn2nc(C)cc21 +O=C(Nc1nccs1)c1c[nH]c2c(C(F)(F)F)cccc2c1=O +CCCc1c(C(=O)N2CCc3cc(F)ccc3C2)[nH]c(C)c1C(C)=O +O=C(NCCN1CCOCC1)Nc1nc(-c2cccnc2)cs1 +N#Cc1ccc(C(O)COc2ncnc3cc(Cl)ccc23)cc1 +N#Cc1ccsc1NC(=O)CCN1CCOC(Cn2cccn2)C1 +COc1ccccc1OCCC(=O)NC(C)CO +Nc1nonc1C(=O)Nc1ccc(Cl)c(F)c1 +CCOC(=O)NCCC(=O)Nc1ccc(C)cc1F +O=C(Nc1ccc(Cl)cn1)C1COc2ccc(F)cc2C1 +c1ccc(-c2nc(CN3CCc4cncnc4C3)no2)cc1 +Cc1cc(N)cc2c1OC(c1ccc(F)cc1)C(=O)N2C +CC(C)c1cc(N)cc2c(CC(=O)NC(C)(C)CO)noc12 +Cc1cc(S(=O)(=O)NC(C)C(C)C)cc(N)c1C +CCCCn1c(N)c(N(C)CCOC)c(=O)[nH]c1=O +CC(C)NC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1 +Cc1cc(C)cc(CN2CCN(c3nccs3)CC2)c1 +CC1(C(N)=O)CN(C(=O)c2ccc(-n3cccn3)nc2)CCO1 +CCc1ccccc1NC(=O)CN(C)C(=O)c1cccc(N(C)C)c1 +Cc1cc(NC(=O)C(C)Nc2cccc(OCC(N)=O)c2)no1 +COC(C)(CNS(=O)(=O)C(C)C)c1cccc(Cl)c1 +Cn1c(CNC(=O)COc2cccc(C(N)=O)c2)nc2ccccc21 +Cc1csc(NC(=O)C2(C)Sc3ccccc3N(C)C2=O)n1 +C=CCN1CCC2(CN(C(=O)Cc3ccccn3)CC2C)C1=O +O=C(CCn1cncn1)NCCOc1ccc2c(c1)OCO2 +O=C(CCC(=O)N1CCc2ccccc2C1)c1cccs1 +Cc1n[nH]cc1CNC1=NS(=O)(=O)c2ccccc21 +O=C(CCNC(=O)c1cc2ccccc2[nH]1)NCc1ccco1 +Nc1nc(NC2CC2)cc(N2CCC(C(=O)N3CCCC3)CC2)n1 +CCOc1cc2c(cc1NC(=O)c1cnc(C)cn1)OC(C)C2 +CC(=O)c1cnoc1-c1ccc2c(c1)NC(=O)CO2 +Cc1cc(C)cc(OCCN(C)C(=O)NCc2nnc3n2CCC3)c1 +CCCN(CC1CC1)C(=O)c1cc(-c2cn[nH]c2)nc2c(C)cccc12 +Cc1nc(C(=O)NCC2(c3ccc(F)cc3)CCOC2)cs1 +Cc1cc(Nc2ccc3c(c2)OCCO3)n2ncnc2n1 +Cc1ccc(NC(=O)Nc2ccc(N3CCCS3(=O)=O)cc2)cc1 +CCc1cc(NC(=O)C2(c3ccccc3F)CC2)[nH]n1 +CCOc1ccc(NS(=O)(=O)c2ccc(C#N)cc2)c(C)c1 +Cc1ccn(-c2ccc(C(=O)Nc3nc[nH]n3)cc2)n1 +Cc1ccc(OC(C)C(=O)NC2C3CCOC3C2(C)C)cc1 +O=C(Nc1ccc(NC(=O)C2CC2)cc1)c1cc(F)ccc1F +Cc1ccc(S(=O)(=O)NCc2ccoc2)cc1C(N)=O +CCOc1cc(CNC(=O)c2cc[nH]n2)ccc1OC(F)F +CNC(=O)c1cccc(NC(=O)c2ccc(CNC(N)=O)cc2)c1C +CCC(NC(=O)C1CC=CC1)c1nc2ccccc2[nH]1 +CC(C)(C)NC(=O)CNC(=O)c1cccc(-n2cccc2)c1 +COCCOc1cccc(NC(=O)Nc2ccccc2F)c1 +CC(C(=O)N1CCOCC1)N1CCN(C(=O)Nc2ccccc2)CC1 +O=C(NCCc1ccc(Cl)cc1)C1CCN(c2ccccc2)C1=O +NC(=O)C1Cc2ccccc2CN1C(=O)CCOc1ccccc1 +COCCCN1C(=O)CCC2CN(c3nccc4occc34)CCC21 +COc1cccc(C(=O)N(C)Cc2ccc(Cl)cc2)c1OC +COc1cccc(CC(=O)NCC(C)(O)c2ccco2)c1 +Cc1ccccc1-n1ncc(C(=O)N2CCOC(C)(C)C2)c1C +CCC(C)NC(=O)c1cc(C(C)C)nc2onc(C)c12 +CC(c1nc(-c2ccco2)no1)N1CCc2ccccc2C1 +COC(=O)CN1CCCN(C(=O)Nc2nc(C)c(C)s2)CC1 +CC(=O)c1c[nH]c(C(=O)Nc2cc(C(F)(F)F)ccc2O)c1 +COc1ccc(-c2cc(CNC(=O)c3cc(C)oc3C)no2)cc1 +CCOC(=O)C(C)(C)N(C)Cc1cc2ccccc2[nH]c1=O +Brc1cncc(-c2nc3ccc(-n4cnnc4)cc3o2)c1 +Cc1cccc(OC2CCN(C(=O)c3cc(C)on3)CC2)n1 +CC(=O)c1cccc(NC(=O)Cn2cnc(C)cc2=O)c1 +CN(CC1CCCO1)C(=O)c1ccc2ccccc2c1O +CC(C)(C)OC(=O)N1CCC2(CCc3ccc(O)cc3O2)C1 +COC(=O)C1CCN(C(=O)c2ccc(-c3nc(C)no3)cc2)CC1 +COc1cccc2c1OCC(NC(=O)N1CCOCC1C1CC1)C2 +CCS(=O)(=O)N1CCN(Cc2cccs2)CC1 +CNC(=O)CNC(=O)Cc1cccc(OC(C)C)c1 +CCOc1ccccc1N(C)C(=O)c1cscn1 +CCOC(=O)CN(C(=O)C1CCOCC1)c1ccc(F)cc1 +CCc1cc(=O)[nH]c2cc(NC(=O)c3cc(C4CC4)on3)ccc12 +CCCC(C)CNC(=O)C(N)c1cc(F)ccc1C +CCc1ncc2c(n1)CN(C(=O)c1cccc(-c3nc[nH]n3)c1)C2 +O=C(COc1ccccc1)NCC(=O)N1CCCc2ccccc21 +O=C(Nc1ccc(N2CCCCC2)nc1)c1ccccc1 +O=C(OC1CCOC1)C1CC(=O)N(Cc2ccccn2)C1 +CCc1nc(N)nc2c1C(=O)CC(c1ccc(F)cc1)C2 +O=C1CCC2(CCN(C(=O)c3ccsc3)CC2)N1 +COCCOc1ccc(C(=O)Nc2cc(N)ccc2F)cc1 +Cc1cc(F)ccc1CCNC(=O)NCc1ccc(C#N)cc1F +Cc1cc(NC(=O)C(C)Cc2ccccc2F)ccc1C(=O)N(C)C +Cc1cc(Cl)ccc1NCC(O)c1ccc(F)c(N)c1 +Cc1cc(NC(=O)C(C)Cc2ccc(Br)cc2)c[nH]c1=O +CCOc1ccc(C(=O)CCN2CCOCC2)c(C)c1C +C=CCN(C)C(=O)c1csc(NC(=O)c2c(F)cccc2F)n1 +COc1cccc(-c2cc(CNC(=O)c3cc(C(C)C)on3)no2)c1 +CC(C)(C)c1nnnn1CC(=O)NC1CCOCC1 +CC1CC1CNC(=O)c1ccc(Cn2cccn2)cc1 +O=C(Nc1ccccc1N1CCCC1=O)c1nccc2ccccc12 +CCn1nc(-c2nn3c(Cc4c(C)noc4C)nnc3s2)cc1C +CCOC(=O)Nc1ccc2c(c1)nc1n2CCN(C(C)C)C1 +O=C(OCCOc1ccccc1)C1CCN(C(=O)c2ccoc2)CC1 +O=C1CCCCN1CCc1ncnn1-c1cccc(F)c1 +O=C(c1c(F)cccc1Cl)N1CCC(Oc2cccnc2)CC1 +CCc1ccc(S(=O)(=O)Nc2ccc3c(c2)CCC(=O)N3)s1 +CCN(CC)C(=O)Cn1cc(S(=O)(=O)CC#N)c2ccccc21 +COCCCn1ccc(NC(=O)Nc2ccc(NC(C)=O)cc2)n1 +O=C(CCc1c[nH]c2ccccc12)N1CCOCC1C1CC1 +N#Cc1ccccc1NCCC(=O)c1ccc(F)cc1 +Cn1c(SCc2coc(-c3ccccc3)n2)n[nH]c1=O +Cc1cscc1C(=O)N1CCC(OCc2ccccc2F)CC1 +Cc1ccc(Cl)cc1-n1ncc2c(NC3CC3)ncnc21 +COc1ccccc1CNC(=O)N(C)CCC(F)(F)F +Cc1nc2cc(NC(=O)c3cccc(N(C)C)c3)ccc2o1 +Cn1cnc(CNC(=O)Nc2cccc(OCC(F)(F)F)c2)n1 +O=C1OC(C(=O)NCc2ccccc2)Cc2ccc(Cl)cc21 +Cn1cnc(CNC(=O)NC2CCCCC2Cc2ccccc2)n1 +COc1ccc(F)cc1C(=O)CNc1ccccc1C#N +CCCN(CC(F)F)S(=O)(=O)c1ccc(F)c(NC(C)=O)c1 +Cc1nc(C)c(C(=O)N2CCN(Cc3cccnc3)CC2)s1 +CN(CC(=O)NCc1cnn(-c2ccccc2)c1)S(C)(=O)=O +COc1cccc(CC(=O)Nc2ccc(-n3ccnc3)nc2)c1 +Cc1cc(C)n2ncc(C(=O)Nc3ccn(C)n3)c2n1 +CCCCN(CC)C(=O)c1cc(C(N)=O)cs1 +CC(=O)N(C)C(c1ccccc1)c1nnnn1-c1c(C)cccc1C +CN(Cc1ccco1)c1nnnn1-c1ccccc1 +Cc1ccsc1CNc1cnn(-c2ncccn2)c1 +CCc1cc(C(=O)N2CCCC2c2cc[nH]n2)on1 +O=C(Nc1ccncc1)C1CCN(C(=O)c2ccncc2Cl)CC1 +CCN(Cc1cccc(F)c1)C(=O)COc1ccccc1NC(C)=O +Cc1ccc(-n2ccnc(NCc3cccs3)c2=O)cc1F +CC(C)(C)C(=O)N1CCC2(CC1)CC(NC(=O)c1ccccn1)CO2 +Cn1c(=O)c2sccc2n(CC(=O)N2CCCCC2)c1=O +CCOC(=O)N1CCC(NC(=O)Cn2cccn2)CC1 +COC(=O)Nc1cccc(NCC(=O)N2CCCC(C)C2)c1 +CNc1ncc(S(=O)(=O)NCC(C)C)cc1Cl +Fc1ccc(Cl)cc1NCc1nc(-c2ccco2)no1 +COc1cccc(NCc2c[nH]nc2-c2cccnc2)c1 +COc1ccc(Cl)cc1-n1nnc(CO)c1-c1ccncc1 +Cc1cc(C)cc(-n2ccnc2SCC(=O)OCC(N)=O)c1 +CCN(C(=O)C(C)N1CCN(c2ncccn2)CC1)c1ccccc1 +CCCS(=O)(=O)NCc1ccccc1NS(C)(=O)=O +O=C(Nc1ccc2c(c1)OCCO2)c1cccn2nccc12 +O=C(COCC(F)(F)F)Nc1ccc(C(=O)N2CCCC2)cc1 +CCN(CC(=O)Nc1nnc(C)s1)c1ccccc1 +COc1cccc(CNC(=O)N(C)Cc2cc(F)c(F)c(F)c2)n1 +Oc1ccc2c(c1)OCC2NCCc1ccncc1 +O=C(NCc1ccccn1)C1CCC(=O)N1Cc1ccco1 +O=C(c1ccoc1)N1CCC2(CC1)CC(OCc1cccnc1)CO2 +CCc1ccc(C(=O)NCc2ccc(Cn3ccnc3)cc2)s1 +COc1ccc(C(C)N(C)C(=O)c2c[nH]c3ccccc3c2=O)cc1 +CCOC(=O)c1ccc(S(=O)(=O)NCC(N)=O)cc1 +Cc1cc(C(=O)N2CCCC(CCc3ccc(F)cc3)C2)[nH]n1 +CCN(CC(=O)Nc1c(F)cccc1F)C(=O)c1ccc(C#N)cc1 +C#CCC(OC(=O)Cc1ccc(N2CCCC2=O)cc1)c1ccccn1 +COc1cc(C2NCCc3c(F)cc(O)cc32)ccc1C +Fc1ccc(-c2nnc(CN3CCc4cncnc4C3)o2)cc1 +Cc1csc(NC(=O)N2CCC(c3nc4ccccc4[nH]3)CC2)n1 +COc1cccc(Nc2ccccc2C(=O)NCc2noc(C)n2)c1 +O=C(Nc1cn[nH]c1)Nc1cccc(C(=O)N2CCc3ccccc32)c1 +CCOc1ccccc1C(=O)Nc1ccc(C)c(-n2cnnn2)c1 +CN(C(=O)c1ccoc1)c1ccc2ccccc2c1 +N#CC(NC(=O)c1cccc(Cl)c1)c1ccc2c(c1)OCO2 +CC(C)CN(C)C(=O)c1cccc(S(=O)(=O)N(C)C)c1 +CCNC(=O)CCSc1ccc(Br)cc1 +COc1ccc(-c2nc3[nH]c(-c4ccc(OC)cc4)cc(=O)n3n2)cc1 +COCCn1cc(Nc2nc(-c3cccnc3)nc3ccccc23)cn1 +COc1ccc(CNC(=O)CSc2nc(C)cc(C)c2C#N)cc1 +CCCCn1cc(CO)c2c(OC)cc(OC)cc21 +CC(C)c1ncc(N2CCOC(C)(C)C2)c(CO)n1 +O=c1ccc(-c2ccco2)nn1C1CCc2ccccc2N=C1O +CCCn1c(C)nnc1SCc1nc(C)c(C)o1 +NC(=O)C1CCN(C(=O)c2ccc(OCC3CC3)cc2)C1 +COc1cccc(C(=O)Nc2sc(C(C)C)cc2C(N)=O)c1OC +CCOCCCNC(=O)C1CCN(c2ccc(F)c(F)c2)C1=O +CCCc1nc2ccc(Br)cc2c(=O)o1 +Cc1ccc(C(=O)NC(C)C(=O)N2CCCC2)n1C +CCN(CC)c1ccc(C(=O)Nc2cnc3c(c2)c(C)nn3C)cc1 +c1cnc(N2CCCC(c3ccnc(Nc4cncnc4)n3)C2)nc1 +CN1C(=O)COC2CN(c3cc(C(F)(F)F)ncn3)CC21 +CCCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)c1ccncc1 +CS(=O)(=O)c1ccc(Oc2ncc(-c3ccc(F)cc3)cn2)cc1 +CCCOC(=O)c1cc(-c2c[nH]c3ccccc23)nn1C +COc1ccc(C(=O)Nc2nc3c(s2)CCC3)cn1 +COc1ccc(C(=O)NCCOc2ccc(F)cc2)cc1 +Cc1ccc(N2CC(C(=O)NCC3CC3)CCC2=O)cc1C +NS(=O)(=O)N1CCN(Cc2nc(-c3ccc(F)cc3)no2)CC1 +Cc1ccc(F)cc1NC(=O)CSc1nn2cnnc2o1 +Cc1ccc(NC(=O)C2CCN(c3ccc(F)c(F)c3)C2=O)c(F)c1 +Cn1cnc(CNC(=O)N(Cc2ccco2)Cc2cccs2)n1 +Cn1cc(C(=O)Nc2ccc(OC(=O)C3(O)CCCC3)cc2)cn1 +CC(C)Oc1ccc(-c2cc(C(C)(C)O)c(=O)[nH]n2)cc1 +CC(C)(C)n1cc(C(=O)N2Cc3ccccc3CC2C(N)=O)cn1 +CCN(Cc1ccccc1)S(=O)(=O)N1CCC(n2cccc2)C1 +CC(=O)Nc1cccc(C(=O)NC(C)c2cc3ccccc3o2)c1 +CCCc1cc(C(=O)NCCNC(C)=O)sc1C +CCOCC1CCCN(C(=O)CCNC(=O)C2CCCCC2)C1 +COCCNC(=O)c1sc(-c2ccccc2)nc1C +COc1ccc(N)cc1-n1c(C)nc2ccccc2c1=O +Cn1c(SCC(=O)NC(C)(C#N)C2CC2)nc2ccccc2c1=O +Cc1nc(C(C)C)[nH]c(=O)c1C(=O)N1CCC(c2ccc(F)cc2)C1 +NC(=O)C1CCCN1C(=O)CSc1ccc(Cl)cc1 +Cc1cc(NC(=O)c2cccnc2Sc2ccccc2)ccn1 +Cc1cc(NC(=O)CSc2nccn2-c2ccc(F)cc2)no1 +CCCOc1ccc(-c2nc(C#N)c(NCc3cccnc3)o2)cc1 +Cc1occc1-c1nn(CC(=O)N2c3ccccc3CC2C)c(=O)o1 +COc1ccc(C2=C(C)C(NCC3CCCO3)=NS2(=O)=O)cc1 +CC(CC#N)C(=O)Nc1ccc(Cl)c(Cl)c1 +CCN(CC(=O)Nc1ccccc1OC)C(=O)CC1CCCC1 +COC(=O)c1ccc(CSc2nnnn2-c2ccc(C)cc2C)o1 +COc1ccccc1CN(CC(F)(F)F)C1CC1 +CCCCCNC(=O)c1sccc1S(N)(=O)=O +Cn1c(SCc2ccc(Cl)cc2)cc(=O)n(C)c1=O +O=C(Cc1csc(N2CCCC2=O)n1)NCCc1cccc(F)c1 +O=C(COc1ccccc1)NCCc1nc(-c2ccccc2)cs1 +CCn1cc(CN2CC3CCCC3(C(=O)OC)C2)cn1 +O=C1CNc2cc(Cl)ccc2N1Cc1ccccc1 +CC(=O)NCC(=O)N(Cc1ccccc1)C(C)C1CC1 +CC(=O)NCc1ccc(C(=O)Nc2cc(C)on2)cc1 +Cc1ccccc1CN1CCN2C(=O)N(Cc3cccnc3)CC2C1 +O=C(Nc1cccc(F)c1)c1c[nH]c2ccccc12 +COc1ccc2c(c1)cc(C(=O)NC(C(N)=O)c1ccccc1)n2C +Cc1cc(NC(=O)NC2CCN(c3c(F)cccc3F)C2=O)no1 +COc1ccc(C(=O)NCc2c(C)nn(C)c2C)c(N)c1 +Cc1cccc(CN2CCN(C(=O)NC(C)C3CCCO3)CC2)c1 +Cc1ccc(C)c(-c2nnc(NC(=O)c3nn(C)cc3C)o2)c1 +CC(=O)c1ccc(NC(=O)c2nn3ccccc3c2Cl)cc1 +CC(C)c1nnc(NC(=O)CS(=O)(=O)c2ccccc2)s1 +CCN(Cc1nc(-c2ccccc2)no1)C(=O)c1ccoc1C +O=C(NCCN1CCNC1=O)Nc1ccc(C(F)(F)F)c(F)c1 +Cc1ccc(C(=O)N(C)C2CCc3ccccc32)c(=O)[nH]1 +Cc1ccc2c(CC(=O)Nc3ccc4c(c3)OCO4)coc2c1 +Cn1ccc(C(=O)NCC(c2cccs2)N2CCOCC2)cc1=O +Nc1ccc2c(Br)cnc(N3CCCC3)c2c1 +CCN(CC(O)COc1ccc2ccccc2c1)S(=O)(=O)O +CCCCN1CC(C(=O)NCCc2c[nH]c3ccc(C)cc23)CC1=O +COc1ccc(OC)c(C(C)NC(=O)Nc2ccccc2)c1 +COc1ccc(CCNC(=O)c2ccc(CNC(C)=O)cc2)cc1 +CCn1cnnc1CNC(=O)COc1ccc(C(C)(C)C)cc1 +O=C(CCNC(=O)c1ccc(F)cc1)Nc1nc[nH]n1 +Cc1ccccc1C(=O)N1CCOc2ccc(F)cc21 +CCCc1nnc(NC(=O)CN2CCCCC2=O)s1 +CNC(=O)c1ncc(OC(C)(C)C)cc1OC1CC1 +CCN(Cc1ccccc1)C(=O)CSc1nncn1C +Cc1nnc(NC(=O)CSc2ncnc(N)n2)s1 +Cc1sc2nc(COC(C)C)nc(N)c2c1C +CCOc1c(OC)cccc1C(=O)NCc1ccccc1 +CCNS(=O)(=O)C1CCOCC1Cc1ccc(F)cc1 +Cc1nc(NC(=O)CCCn2cccc2)sc1C(=O)N(C)C +CCC1CCCCN1C(=O)CNC(=O)c1ccc(OC)c(OC)c1 +O=C(CCc1nc(-c2ccncc2)no1)Nc1ccccn1 +COC(=O)C1NCCc2ccc(S(C)(=O)=O)cc21 +CNC(=O)c1cc(NC(=O)Cc2cccc(OCC#N)c2)ccc1F +CCNC(=O)CNc1ccc(NC(=O)c2cccc(C)c2)cc1 +Cc1ccc(CNC(=O)c2cc(NC(=O)c3ccccc3)n(C)n2)o1 +CC(C)N(C)C(=O)Cc1ccc(Cl)cc1Cl +CS(=O)(=O)N1CCC2(CC1)CNC(=O)c1ccccc1O2 +COc1ccccc1OCCN(C)C(=O)c1cn2cccnc2n1 +NC(=O)CNC(=O)c1cccc(OCc2cccc(F)c2)c1 +CC(NC(N)=O)C(=O)NC(C)c1cccc(N2CCCC2)c1 +Cc1ccc(C(C)(C)C)cc1C(=O)CN1CCOCC1 +Cn1c(COc2ccccc2C(N)=O)cc(=O)n(C)c1=O +O=C(Nc1cnc2sccn2c1=O)OCc1ccccc1 +CCOC(=O)c1sc2ncnc(N(C)C3CCN(C)C3=O)c2c1C +O=C(Cc1cccc(O)c1)NCc1nnc2n1CCCCC2 +C=CCn1c(C2CC2)nnc1S(=O)(=O)Cc1ccc(C#N)cc1 +O=C(Nc1ccccn1)C1CCN(C(=O)COc2ccccc2F)C1 +COc1ccccc1NC(=O)Nc1ccc(OCC#N)cc1 +Cc1ccc(N2CC(C)N(Cc3cccc(C)n3)CC2=O)cc1 +COc1ccc(CC(CO)Cc2ccccc2)cc1OC +Cc1ccccc1OC(=O)c1cn(CC(=O)N(C)C)nn1 +CC(=O)N1CCCC(c2cc(C(F)(F)F)c3c(N)ncnc3n2)C1 +COc1nccnc1N1CCC(NC(=O)c2ccc(C)s2)C1 +CCCN(CC(F)F)C(=O)NCc1ncn(C)n1 +O=C(NCc1nc(C2CC2)no1)c1cc2ccccc2c(=O)[nH]1 +CCCn1nccc1NC(=O)Cc1c(C)nc(C)[nH]c1=O +CCn1cc(NC(=O)c2ccc(-c3nc(C)no3)cc2)ccc1=O +Cc1csc(CCCNC(=O)N2CCc3cc(F)ccc3C2)n1 +COC(C)CCOC(=O)C1CCOc2ccccc21 +CC(CNc1ccccc1)NC(=O)c1ccncc1F +Cc1sc(=O)n(CC(=O)Oc2cccc(F)c2)c1C +Cc1cc(=O)oc2cc(OCC(=O)NC(C)C3CC3)ccc12 +CCCn1c(=O)n(CC(O)c2cccc(F)c2)c2ccccc21 +CCc1ccc(CN(C)C(=O)CNC(=O)c2ccccc2Cl)cc1 +O=C(CCNc1ncccn1)N1CCN(c2ccc(Cl)cn2)CC1 +CCOc1cc(NC(=O)NCCC(C)C)ccc1OC +COC(=O)c1noc(C(=O)Nc2ccccc2F)c1N +NC1CCCN2CCc3cccc(Br)c3C12 +Cc1ccccc1NC(=O)c1cc2cnc3[nH]ccc3c2n1C +O=C(Nc1cncnc1N1CCCC1)c1cccc(Cl)c1Cl +COc1cccc(C(=O)NCC(=O)Nc2cccc(F)c2)c1OC +Cc1cc(C)n(CCNc2cc(OC(C)C)nc(N)n2)c(=O)n1 +COc1ccccc1CN(C)C(=O)c1cn(Cc2ccccc2)nn1 +Cc1ccc(Cl)cc1NC(=O)CCCNC(=O)c1cccs1 +COc1ccc(Br)c(C(=O)N(C)Cc2cccs2)c1 +COc1ccc(CC(=O)Nc2c3c(nn2C)CCC3)cc1OC +O=c1c2ccccc2cnn1Cc1ccc(OC(F)F)cc1 +O=C(NCc1cccc(F)c1)Nc1ccn(CCN2CCOCC2)n1 +CN(Cc1ccc(F)cc1)c1ccc(S(N)(=O)=O)cn1 +CCCC(C)N1CC(C(=O)NCc2ccnc(OC)c2)CC1=O +O=C(Nc1cccc(-c2cn[nH]c2)c1)c1ccccn1 +CCc1nc(CC(=O)N(C)Cc2cccnc2)cs1 +Cc1cnc(NC(=O)c2cnn3c(C(F)F)cc(C4CC4)nc23)s1 +Cn1cc(NC(=O)Cn2ccc3cc(Br)ccc32)cn1 +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)NCC1(C)CCCC1 +Nc1ccc2c(c1)CN(C(=O)c1cccnc1)CC2 +CCn1cc(CCC(=O)NCc2cccc(C(F)(F)F)c2)c(C)n1 +O=C(c1ccc(N2CCCC2=O)cc1)C1CCCC1 +CC(C)(Oc1cc(Cl)ccc1Cl)C(=O)N1CCOCC1 +CCCn1nc(-c2c(C)cc(C)cc2OC)cc(CO)c1=O +Cc1nnnn1-c1cc(NC(=O)N2CCCC(C)C2CO)ccc1F +O=C(c1c[nH]c(=O)c(Cl)c1)N(C1CCCC1)C1CC1 +N#Cc1ccc(CNc2ccc(-n3cncn3)cc2)c(F)c1 +Nc1cc(-c2cncc(C(=O)N3CCOCC3)n2)c2cc[nH]c2n1 +O=C(c1cnc(C2CC2)[nH]c1=O)N1CCOC(C(F)(F)F)C1 +CCOc1nnc(CN2CCOC(Cn3cccn3)C2)s1 +C=CCNC(=O)c1cc(S(=O)(=O)N(C)C)ccc1N1CCCC1 +COc1ccccc1-c1nnn(CC(=O)Nc2ccccc2C)n1 +CC(NC(=O)Cn1ccc2ccccc21)c1ccncc1 +CCCn1c(C)nnc1CN(C1CC1)S(=O)(=O)c1cccnc1 +CC(Cc1ccccc1F)NC(=O)N1CCC(N2CCNC2=O)CC1 +CN(C)c1nc(N)nc(CN(Cc2cccs2)C2CC2)n1 +O=C(NCCOCc1ccccc1)C1CCC(=O)N(C2CC2)C1 +c1cnn(CC2CN(c3ncnc4[nH]ccc34)CCO2)c1 +Cn1cc(CC(=O)OCC2CC(=O)N(C3CC3)C2)c2ccccc21 +Cc1cc(C(C)NC(=O)c2c(C)oc3nc[nH]c(=O)c23)c(C)s1 +CC1CC1C(=O)N1CCN(c2ccc(C(N)=O)cc2)CC1 +CC(NS(=O)(=O)CCn1ccc2ccccc2c1=O)c1ccco1 +COc1ncc(Br)cc1C(F)(F)F +COC(=O)CNC(=O)c1ccccc1Oc1ccccc1 +CCC(C)NC(=O)N1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +Oc1cccc(CN2CCC(CN3CCOCC3)C2)c1 +NC(=O)CCC1CCN(C(=O)c2c(F)cc(F)cc2F)CC1 +COc1cc2nc(CNC(C)C(C)(C)C)[nH]c(=O)c2cc1OC +CCCCN(C)C(=O)NCc1ccc(S(=O)(=O)NC)cc1 +CC(=O)NCc1cc(-c2ccc3c(c2)CC(C)O3)on1 +Cc1ocnc1C(=O)NC1CCCC1c1ccccc1C(F)(F)F +CN(Cc1ccc(C#N)cc1)C(=O)c1ccn(C)c(=O)c1 +CCCC1CN(C(=O)NCC(C)(C)c2ccncc2)CCO1 +Cc1ccc(C)c(OCC(=O)Nn2c(C)nc3ccccc3c2=O)c1 +O=C(Nc1cc(Cl)cc(Cl)c1)c1nc(-c2cnccn2)no1 +COc1ccccc1OC(C)(C)C(=O)N1CCNCC1 +COc1ccc(OCCCNC(=O)c2ccc(F)nc2)cc1 +CC(C)OCCC(=O)Nc1c(Cl)cc(N)cc1Cl +CCN1CCN(C(=O)Cn2nc(C)c(Br)c2C)CC1 +CC(=O)Nc1cc(NCc2cccc(Cl)c2F)ccc1F +Cc1nc(-c2c[nH]c(C(=O)N(CC3CCOC3)C3CC3)c2)cs1 +COc1ccccc1CNc1ccccc1-n1ccc(C)n1 +Cc1ccc(C(=O)N2CCN(Cc3ccccc3)C(C#N)C2)s1 +COc1ccccc1NC(=O)Cc1nc(-c2ccccn2)n[nH]1 +CSc1ccccc1C(=O)N1CC(C)CC(C)C1 +O=C(Nc1ccc2c(c1)COC2)N1CCOC(c2cccc(O)c2)C1 +Cn1cccc1C(=O)N1CCC2(CC(Nc3cccnc3)CO2)C1 +CCn1c(=O)oc2ccc(C(=O)Nc3nc4ccccc4s3)cc21 +Cc1cc(OCCCC(=O)NCc2cscn2)ccc1Cl +O=C(COc1ccccc1)Nc1cnc(N2CCCC2)nc1 +CC(C)Oc1nnc(SC(C)C(=O)Nc2cccc(C#N)c2)s1 +O=C(c1cc2c(s1)CCCC2)N1CCCOC(Cn2cccn2)C1 +O=C(CCNC(=O)c1ccsc1)NCCC(=O)N1CCCC1 +C=CCCC(=O)Nc1ccnn1-c1cccc(Cl)c1 +Cc1ccc(NC(=O)c2cn(C)nc2C)cc1S(=O)(=O)NC1CC1 +COc1ccccc1Oc1ccc(CNC(=O)C2CCCO2)cc1 +CCC(=O)Nc1cccc(NC(=O)N2CCOCC2CC(C)C)c1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1n[nH]c2ccccc12 +N#CCCN(Cc1ccco1)C(=O)c1cccc(Oc2ccccc2)c1 +Cc1cc(C(=O)NC(C)C(=O)NCC2CC2)no1 +CN(Cc1coc(-c2ccc(S(C)(=O)=O)cc2)n1)CC(F)F +CCN(CC)C(=O)CCC(=O)NC(C)c1ccc2c(c1)OCCO2 +CCc1nnc(CN2c3cccc4cccc(c34)S2(=O)=O)o1 +CCC(NC(=O)c1ccccc1Br)c1ccccc1 +CC(NC(=O)Nc1ccccc1CC(N)=O)c1nc2ccccc2[nH]1 +Cc1cc(Cl)ccc1OC(=O)C1CCCN(C(=O)c2ccoc2)C1 +C=CCCC1NCCc2ccc(Cl)c(Cl)c21 +O=C(NCc1ccco1)N1CCC(n2c(=O)[nH]c3cncnc32)C1 +COc1cccc(-n2nnc(C#N)c2-c2cccs2)c1 +Cc1cnc(NC(=O)C2(c3cc(-c4ccccc4)on3)CC2)s1 +O=C1COc2ccc(S(=O)(=O)NCCCO)cc2N1 +O=C(Oc1ccc(NC(=O)C2CC2)cc1)c1cn[nH]n1 +COCCNC(=O)C1(c2ccc3c(c2)OCCO3)CCCC1 +Cc1occc1C(=O)N(CCC#N)c1ccccc1 +O=C(Cn1cccc(C(F)(F)F)c1=O)c1ccc2ccccc2c1 +CCCNC(=O)CCNC(=O)Nc1ccc(CC#N)cc1 +C#CCOC(=O)Cn1nc(-c2cccs2)oc1=O +Cc1ccc(-c2n[nH]cc2CNc2cccc(-c3noc(C)n3)c2)o1 +CCC(O)(CC)CNC(=O)NC1CCN(C(C)=O)CC1 +O=C(CSc1nnnn1-c1ccc(Cl)cc1)Nc1ccccc1 +Cc1c(O)c2ccc(N)cc2n(CCCC#N)c1=O +CC(=O)N1CCc2cc(C(=O)N3CCC(OCC(C)C)CC3)ccc21 +COC(=O)c1ccoc1COC(=O)c1ccc(C(N)=O)cc1 +Cc1ccccc1N1CCCN(C(=O)C2(C)CCCCO2)CC1 +O=S(=O)(c1cc(F)ccc1F)N1CCNCC1 +CCCC(C)N1CC2(CCN(C(=O)c3ccnn3C)CC2)OC1=O +Nc1ccc(C(=O)NCc2nc(-c3ccccc3)n[nH]2)cc1 +CC(OC(=O)Cn1nc2ccccn2c1=O)c1ccc(Cl)cc1 +Cc1ncsc1C(=O)N1CCN(Cc2cccs2)CC1 +Cc1cc(C(=O)N(C)C)c2c(-c3ccccc3F)noc2n1 +O=C(Nc1ccc2c(c1)COC2)c1cccc(-n2ccnc2)c1 +O=C1CC(C(=O)NCc2cn3c(n2)SCC3)c2cc(F)ccc2N1 +CC(C)(C(=O)NCc1ccncc1)c1ccccc1 +O=C(C1CCCN(c2nc3ncccc3n3cccc23)C1)N1CCCC1 +O=C(CNc1ccc(Cl)c(OC(F)F)c1)NC1CC1 +CN(Cc1nc2ccccc2s1)C(=O)c1ccc(F)cc1Cl +Cn1ccnc1C(NC(=O)C1CC=CCC1)c1cccc(F)c1 +CC1CN(c2ccc(NC(=O)COC3CCCC3)cn2)CC(C)O1 +O=c1c2ccc(F)cc2ncn1CC(O)COCc1ccco1 +CCc1noc(-c2ccccc2NC(=O)c2cccc(OC)c2)n1 +Cc1c(C(=O)N=c2[nH]c3ccccc3n2C(C)(C)C)cnn1C +CCNC(=O)C(C)NC(=O)NCC(C)(C)c1ccc(Cl)cc1 +CC(C)C(C)NC(=O)CCC1Cc2ccccc2NC1=O +CC(=O)Oc1cccc(C(=O)c2c(F)cccc2F)c1 +CC(C(=O)NCc1cc(Br)cs1)n1cccn1 +Cc1cc(C)nc(NCCCNc2nc(C)cc(C)n2)n1 +COc1ccc(-n2nnc(C#N)c2C(C)C)cc1Cl +Cn1cc(Cl)c(C(=O)Nc2ccc(F)cc2F)n1 +CC(COc1ccc(C(C)(C)C)cc1)NC(=O)C1CCC(=O)N1 +CCCOc1ccc(C(=O)c2nc3c(n2O)CCCC3)cc1 +CC(C)NC(=O)Nc1cccc(C(=O)NCC2CCC(=O)N2)c1 +CC1C(N2CCCC2)=CC(=O)OC1c1ccccc1 +CC(C)NC(=O)CSc1n[nH]c(=O)n1C1CC1 +CCN(CC1CC1)C(=O)c1c(C)[nH]c2ccccc12 +Cc1ccc(F)cc1NC(=O)N(C)Cc1ccoc1C +CCOc1cccc(CN(C(=O)C2(C)CC2)C2CC2)c1 +NC(=O)c1ccccc1OCC(=O)NCc1ccco1 +COc1ccc(-c2nnc3c4cnn(C)c4ncn23)cc1 +Cc1ccc(CN(C)C(=O)C2CCN(S(C)(=O)=O)CC2)s1 +OCc1nnn(-c2ccccc2)c1Cc1ccccc1 +c1cnc(NCCCn2nnc3ccccc32)nc1 +Cc1ccc(OC(=O)c2ccn(C)c(=O)c2)cc1C +CCc1cc(C(=O)Nc2ccc(CN3CCOC3=O)cc2)sc1C +C=CC1CCN(C(=O)Cc2cccc(S(=O)(=O)CC)c2)CC1 +COc1ccc(CN2CCN(C(=O)c3ccc(OC)nc3)CC2)cn1 +CN(Cc1cccc(C#N)c1)C(=O)c1ccc(NC(N)=O)cc1 +COc1ccc(OC)c(CNC(=O)c2ccccc2F)c1 +Oc1ccc(Cl)cc1-c1nc2c3c(ncn2n1)CCC3 +CCS(=O)(=O)c1ccc(NC(=O)CN2CCCCCC2=O)cc1 +CCOc1nn(CC)cc1C(=O)Nc1ccccc1SC +CC(C)NC(=O)CC(C#N)c1ccc(Br)cc1 +CC(=O)NC(C)C(=O)N1Cc2cnn(Cc3ccc(F)cc3)c2C1 +CCOCCCNS(=O)(=O)c1ccc2c(c1)NC(=O)C(C)O2 +Cc1cccc2c1ccn2CCC(=O)Nc1cnn(C)c1 +Cc1cc(C(=O)NCCc2cn[nH]c2)c2ccc(C)c(C)c2n1 +O=C(Nc1ccc(F)c(Cl)c1)N1CCOCC1 +CCN(c1ccc(-c2csc(C3CC3)n2)cc1)S(C)(=O)=O +O=C(Nc1nc(-c2cccnc2)cs1)c1cc(=O)c2ccccc2o1 +COc1cc(C(C)NC(=O)c2cc[nH]n2)ccc1OCCO +Cc1ccc(OC2CCN(C(=O)c3sc(C)nc3C)CC2)nn1 +COc1ccc(S(=O)(=O)N=c2ccc(C)c[nH]2)cc1Cl +CCCCN(CC(N)=O)C(=O)c1ccc(C(=O)N(C)C)cc1 +Nc1cc(C(=O)OCC(=O)NC2CC2)c(Br)cc1F +Fc1cccc(-c2nn3c(-c4ccco4)nnc3s2)c1 +Cc1ccc(CC(=O)Nc2cccc(Oc3ccccc3)c2)cn1 +O=C(CN1CCN(c2nccs2)CC1)NCC(F)(F)F +COc1cccc(COCC(=O)N2CCN(CC(C)O)CC2)c1 +CC(OCC1CC1)C(=O)N(C)c1ccccc1S(C)(=O)=O +COc1cc(F)c(S(=O)(=O)Oc2cccc(F)c2)cc1OC +CCc1nc(CC(=O)NC(C)c2cccc(Cl)c2)cs1 +CCNC(=O)Nc1cc(C(=O)Nc2ccccc2)ccc1C +COc1cc2c(cc1CNC(=O)C1CCCN(C(N)=O)C1)OCCO2 +CCOC(=O)C1CCCN(C(=O)c2ccccc2CC#N)C1 +Cc1ccc(C(=O)NC2CCN(c3ccccc3)C2=O)c(C)c1 +CS(=O)(=O)NC1CCN(Cc2ccoc2)C1Cc1cccnc1 +CNC(=O)C1C2CCC(C2)N1C(=O)c1ccccc1 +O=C(Nc1ccncc1)C1CCCCN1C(=O)c1ccccc1 +CCN(CC)C(=O)c1nnc2ccc(N3CCOCC3)cc2n1 +Cn1c(C(=O)Nc2ccc3c(c2)OCO3)cc(=O)n(C)c1=O +NC(=O)Cc1ccc(OCC(=O)Nc2ccc(Cl)cn2)cc1 +CC(C)(C)c1ccc(=O)n(Cc2cccc3cccnc23)n1 +Cn1c(NCCO)nc2c(c1=O)C1(CCCC1)Cc1ccccc1-2 +NC(=O)c1cccc(C(=O)NCC2(Sc3ccccc3)CC2)c1 +COc1ccc2ncn(C(C)Cc3ccccn3)c(=O)c2c1 +CSc1nc2ccc(NC(=O)Cc3c(C)noc3C)cc2s1 +COC(=O)c1ccccc1NC(=O)c1cc2c([nH]c1=O)CCCCC2 +COc1cccc2c1CCC2NC(=O)c1cnn(-c2ccncc2)c1C +Cc1ncsc1C(=O)N(C)C(C)c1ccccc1F +C=CCC(CC=C)C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +COC(C)(C)CC(C)NC(=O)NCC1(c2ccc(F)cc2F)CC1 +COc1ccc(C(N)=O)c(OCC(=O)NCc2ccccc2Cl)c1 +CN(C)S(=O)(=O)c1ccc2c(c1)CN(CCN)CC2 +O=C1CCN(C(=O)COc2cc(F)ccc2F)CC1 +CN(CCC#N)C(=O)c1cc2c(s1)-c1ccccc1OC2 +O=C(Nc1nncs1)c1cccc(-c2ccoc2)c1 +Cc1occc1C(=O)NCC(=O)N(C)CCC(F)(F)F +Cc1cccc(C)c1OCC(=O)Nc1ncccc1CO +CCc1ccc(NC(=O)Cn2ccc3sccc3c2=O)cc1 +COc1ccc(NC(=O)Nc2ccn(C)n2)c(OC)c1 +Cc1cccc(CNC(=O)c2ccc(C)c(NS(C)(=O)=O)c2)c1 +Cc1ccccc1Cn1cc(-c2ccncc2)cc1C(=O)N(C)C +Cc1noc(C(C)NS(=O)(=O)c2ccc(S(C)(=O)=O)cc2)n1 +CCC(C)Oc1ccc(NC(=O)CCC(=O)N2CCOCC2)cc1 +O=C(c1cscn1)N1CCC(OCC2CC2)C1Cc1ccccc1 +CSc1ccc(NCc2ccc(C#N)cc2)nn1 +O=C(NC1CC=CC1)N(CCO)Cc1ccc(Cl)c(Cl)c1 +CSc1ccc(-c2ccc(=O)n(CC(=O)NC(C)C)n2)cc1 +CCCC(=O)N1CCCC1C(=O)OCc1cccc(F)c1 +Cc1cccc(O)c1NS(=O)(=O)c1cccc(F)c1 +COc1ccc(NC(=O)Nc2cc(NC(C)=O)ccc2F)cc1 +CSc1cc(-c2csc(N3CCCCC3)n2)ccc1NC(C)=O +CC(C)(C)OC(=O)N1CCC(C(O)CC#N)CC1 +COC(=O)c1cc(-c2c(O)cc(O)cc2O)n[nH]1 +Cc1c(NC(=O)CC#N)c(=O)n(-c2ccccc2)n1C +CC(C)(C)c1n[nH]cc1CN1CCCC2(C1)OCCO2 +CCCCCNC(=O)c1cc2c([nH]c1=O)CC(C)CC2=O +COc1c(N)cc(C)cc1S(=O)(=O)N1CCCCC1 +NC(=O)c1ccc(-c2ccccc2Br)o1 +CN1CCOC(CNC(=O)CCC(=O)c2ccc3c(c2)CCCC3)C1 +CCOC(=O)NC(C(=O)N(C)Cc1ccncc1)C(C)C +Cc1cccc(C)c1NC(=O)c1csc(-n2cccc2)n1 +NC(=O)c1cccc(NC(=O)c2cc(Cl)ccc2Cl)c1 +Cc1cc(C(C)NC(=O)c2ccn(C)c(=O)c2)c(C)o1 +O=C(Cc1ccon1)NCc1nc(-c2ccc(Cl)cc2)cs1 +Cc1nc(-c2cccs2)sc1C(=O)OCC(=O)c1ccc[nH]1 +Cc1cnn(C2CCCN(C(=O)c3cc(-c4ccco4)[nH]n3)C2)c1 +Cc1nc(N(C)C)ncc1C(=O)NC(C)Cc1cnccn1 +C#Cc1cccc(NC(=O)NC(CCCC)COC)c1 +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)CCCC3=O)cc1 +COCCCNC(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1C +Cc1cc(NC(=O)N2CCOCC2C)n(Cc2ccccc2)n1 +CCc1onc(C)c1NC(=O)NCC1(Sc2ccccc2)CC1 +CCNC(=O)C1CCCN(S(=O)(=O)c2c(C)nn(C)c2C)C1 +O=C(Cc1ccccc1F)Nc1ccc(-c2ncc[nH]2)cc1 +Cc1ccc(CC(=O)Oc2ccc(C#N)cc2)s1 +COc1ccc(CCNC(=O)Cc2cccc(O)c2)cc1OC +O=C1NC(c2ccc(N3CCCC3)nc2)Nc2ncccc21 +COc1cc(OC)c(C(=O)Nc2ccccc2C(N)=O)cc1OC +Cc1oc(C)c(C(=O)Nc2cnc3c(c2)c(C)nn3C)c1C +C#Cc1cccc(NC(=O)CN(C)C(=O)CCc2cccc(F)c2)c1 +C=CCn1c(SC(C)C(N)=O)nnc1C1COc2ccccc2O1 +COc1ncccc1CNC(=O)Nc1ccc2nc(C)oc2c1 +COc1ccc(Cl)cc1C(=O)CNC(=O)C1CCCC1 +O=C(Cc1ccccc1)NCCC(=O)N1CCC12CCC2 +COc1ccnc(N(Cc2ccccc2OC)C2CC2)n1 +Cn1nccc1CNC(=O)COc1ccccc1-c1ccccc1 +COC(=O)c1cc(-c2sc(-c3cccnc3)nc2C)n[nH]1 +COC(=O)Cn1ncc2c(Oc3ccc(C#N)cc3)ncnc21 +Cc1cc(F)cc2c1CCNC2c1cccc(O)c1 +FC(F)CN1CCN(Cc2ncccc2C(F)(F)F)CC1 +CCN(CC)C(=O)CCNc1cc(C)nc(C)n1 +CCOC(=O)c1csc(NCc2cccnc2)n1 +CCN(CC(C)C)c1c(N)n(CC(C)C)c(=O)[nH]c1=O +O=C(CSc1nncc2ccccc12)NCCc1ccccc1 +O=C(Oc1cccc(F)c1)c1ccc(=O)n(-c2ccccc2)n1 +CC(NC(=O)C1CCCO1)c1cccc(N2CCCC2)c1 +O=C(c1sccc1Br)N1CCN2CCCCC2C1 +Cc1cccc(C)c1NC(=O)c1cnn(-c2ccc(Cl)cc2)c1 +OCCSc1nnc(Nc2cccc(F)c2)s1 +CCNc1cc(-c2ccc(F)cc2)nc2ccnn12 +Cc1nc2ccccc2n1CCNC(=O)c1cc2ccccc2o1 +CC(C)(C)c1ccc(S(=O)(=O)CCNC(=O)N2CCC2)cc1 +CN(CC1(C)COC1)C(=O)CNc1ccc2nncn2n1 +Cc1ccc(N)cc1NC(=O)c1ccc(F)c(F)c1 +Cc1ccc(CNC(=O)C(C)Sc2ccccn2)s1 +CNc1nc2ccc(CCC(=O)OC(C)C)cc2s1 +CCCCCC(C)NC(=O)NC1CCN(C(=O)c2cnccn2)CC1 +CCn1nc(C)c(Cl)c1C(=O)NCc1ccccc1F +O=C(Cc1ccc(N2CCCC2=O)cc1)NCc1ccncc1 +CCOc1cccc(NC(=O)c2cc(-c3csc(C)n3)c[nH]2)c1 +O=C(NCc1cccnc1)c1cc(CN2CCOCC2)on1 +CN(C)c1cc(C(=O)N2CCCC(CNS(C)(=O)=O)C2)ccn1 +CC(C)Oc1ccc(CNC(=O)C(C)Sc2ccccn2)cc1 +Cc1csc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2C)n1 +O=S(=O)(Nc1ccc(F)c(F)c1F)c1cccs1 +CC1CCCCC1NC(=O)c1ccc(S(=O)(=O)N(C)C)o1 +CNC(=O)Cn1cnc(NC(=O)c2c(C)cc(C)cc2C)n1 +CCn1cc(C(=O)Oc2ccc(CC(=O)OC)cc2)cn1 +CC1(C)CN(CC(=O)NC2CCCC2)c2cc(N)ccc2O1 +CC(C)Oc1nc(N(CC2CC2)C(C)C)ccc1N +CN(CCCOc1ccccc1)C(=O)Nc1ccc(F)c(C(N)=O)c1 +COc1ccc(NC(=O)CNc2cccc(SC)c2)cc1 +Cc1ccc(CNC(=O)CCCOc2ccccc2)cc1 +Cn1ncc(N2CCC(CNC(=O)c3cccc(CO)n3)C2)cc1=O +Cc1ccccc1C(=O)N1CCOCC1c1cccn1C +NC(=O)C1CCCC1NC(=O)Cc1csc(Cc2ccccc2)n1 +CN(C)S(=O)(=O)NCC(O)c1ccc2c(c1)OCCO2 +O=C(Nc1ccn(CCc2ccccn2)n1)c1cccc(Cl)c1 +COCC(=O)NCc1cccnc1Oc1c(C)cccc1C +Cc1ccc(CN(C)C(=O)c2cc(CC(C)C)[nH]c(=O)n2)o1 +CN(C)C(=O)COc1ccc(NC(=O)Nc2ccc(C#N)cc2)cc1 +CC(C)(C)OC(=O)CNC(=O)Cc1c(F)cccc1F +O=C(Nc1nnc2ccccn12)NC1CCOC(c2ccccc2)C1 +Cc1cc(C)n2nc(C(=O)N3CC(c4ccccc4C)CC3C)nc2n1 +COc1ccc(C(=O)NCc2noc(C)n2)cc1C#N +Cc1ccc2c(NC(=O)c3ccn(C(C)C)n3)cccc2n1 +O=C(NCCc1ccccc1)N1CCC(C2OCCO2)CC1 +Cc1cc(CC(=O)N2CCC3(CCCN(C4CCCC4)C3=O)C2)on1 +CCCS(=O)(=O)N(CCO)C1CCCCCC1 +Cc1nc(N2CCC(C)CC2)c2cnn(-c3ccc(F)cc3)c2n1 +Cc1ccc(C(=O)CCC(=O)N(C)Cc2cccc(C#N)c2)s1 +Cc1ccc(C(C(=O)NC2CCC(O)CC2)N(C)C)cc1 +Cc1sc(C(=O)Nc2ccccc2C#N)cc1S(=O)(=O)N(C)C +CC(NCCc1ccc2c(c1)CCO2)c1ccc(S(C)(=O)=O)cc1 +COC(=O)Cn1c(SCc2ccccn2)nc2ccccc2c1=O +CCC(=O)Nc1ccc(O)c(C(=O)NCC2CC=CCC2)c1 +CC1CN(Cc2nc(-c3ccsc3)no2)C(C)CO1 +CC(C)(CNC(=O)NC(c1ccccc1)c1cccc(F)c1)C(N)=O +Cc1ccc2oc3c(c(=O)c2c1)C(c1ccc(O)cc1)N(C)C3=O +COc1ccc(C(=O)NCCn2ccc3ccccc32)cc1 +CC(C(=O)NCC1(O)CCC(C(C)(C)C)CC1)n1ccnc1 +Cc1cc(S(=O)(=O)N(C)C)cc(NC(=O)Cn2ccnc2)c1C +C#CCNC(=O)CSc1nc2ccccc2c(=O)n1C +C=CCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 +NC(c1cc(Br)cs1)C(F)(F)F +CC(Oc1c(Cl)cccc1Cl)c1ccnc2ncnn12 +CNC(=O)C1CCN(C(=O)c2cccc(F)c2)CC1 +CCCCC1C=CCN1C(=O)c1ccc(C(C)C)[nH]c1=O +Cc1cccc(C(C)CNC(=O)Cn2cnc3c(cnn3C)c2=O)c1 +O=C(CNC(=O)c1ccsc1)Nc1ccc(Cl)c(F)c1 +Cc1nc(-c2ccc(CCNC(=O)NCCO)s2)cs1 +O=C(CCC1CCCC1)Nc1ccc2c(c1)OCC(=O)N2 +Cn1cccc1C1CCCCCN1C(=O)C1CCC(=O)N1 +CSc1nc(=O)[nH]c(C)c1C(=O)NC(C)CO +Cc1cc(OC(=O)C2CCOCC2)ccc1Cl +CCOCCCNC(=O)C1COc2ccc(F)cc2C1 +Cc1cc(NC(=O)C2CCCCN2C(=O)c2cccs2)n(C)n1 +CC(C)CNC(=O)c1ccc(NC(=O)NC(C)C(C)C)cc1 +O=C(CCNC(=O)c1cc2ccoc2cn1)NC1CCCC1 +N#CCCN(CCC#N)C(=O)CSc1ccc(Cl)cc1 +C=CCn1cnnc1SCC(=O)NCc1cc(C)c(O)c(C)c1 +COc1ccc(C)cc1N1CC(C(=O)NCC(C)C)CC1=O +CCC1CN(C(=O)C2CC2)C(CC)CN1C(=O)C1CC1 +Cc1oc(C(=O)OCC(C)(C)C)cc1S(=O)(=O)N(C)C +Cc1ccc(OCC(=O)NCc2nncn2C)c(Br)c1 +Cc1nc(C2CCCN(C(=O)Cc3c[nH]c4cccc(C)c34)C2)no1 +CNC(=O)C(C)n1nc(-c2ccccc2)ccc1=O +CNS(=O)(=O)c1ccc(C)c(C(=O)N(C)Cc2cccs2)c1 +CC(=O)Nc1cccc(NC(=O)N(C)Cc2ccc(Cl)cc2)c1C +CC(C)c1cc(=O)n2c(n1)SCC2CC(=O)N1CCCCC1 +CC(=O)NC(C(=O)Oc1ccc(Cl)cc1Br)C(C)C +Cc1cc(N)c2onc(CC(=O)N(C)C3CCCCC3)c2c1 +C#CCNCc1cc(Cl)cc(OC)c1OC(C)C +CCN1C(=O)NC(C)(C)CC12CC(C)(C)NC(=O)N2CC +Cc1ccc(S(=O)(=O)C2(C(=O)Nc3ccc(C)c(F)c3)CC2)cc1 +COCCn1cnnc1SC(C)C(=O)Nc1cccc(Cl)c1 +Cc1cc(C)n(CCC(=O)Nc2cccc(N)c2)n1 +Cc1ccc(N2CC(C(=O)Nc3ccc(O)cc3)CCC2=O)cc1C +CCS(=O)(=O)N1CCCC1C(=O)c1ccc(F)c(F)c1 +Fc1ccc(C(F)(F)F)c2c1CCNC2c1cccnc1 +COc1cccc(C(=O)Nc2ccc(CN3CCOC3=O)cc2)c1 +CCc1nsc(SCCCCC(=O)N(C)C)n1 +CC(C)(C)C(=O)Nc1ccc(C(=O)NCC2CCCO2)cc1 +COc1ccc(N2CCN(CC(=O)NC(C)(CO)CO)C2=O)cc1 +Cc1ccc(C(C(=O)NC2CCOCC2)N(C)C)cc1 +Cc1ccc(C(=O)CNc2ccccc2C#N)c(C)c1 +Cc1cnn(CCC(=O)Nc2ccc(-c3nc(C)cc(=O)[nH]3)cc2)c1 +Cc1noc(C)c1S(=O)(=O)Nc1ccc(Br)cc1 +c1cnc(OC2CCN(c3nnc(C4CC4)o3)CC2)nc1 +Cc1cc(C(=O)N2CCCC3(C2)NC(=O)c2ccccc2N3)on1 +CC(O)CNC(=O)c1cc(C2CC2)nc2ccc(F)cc12 +CC(C(=O)N1CCCC1)N1CCN(C(=O)CCC2CCCO2)CC1 +O=c1cc(-c2ccccc2)oc2cc(O)cc(O)c12 +CCCC(=O)Nc1ccc(CNC(=O)CNC(=O)NC)cc1 +O=C(c1ccc2ccccc2n1)N1CCC(Nc2cccnc2)C1 +CC(C)(C)CC(=O)N(c1cccc(O)c1)S(C)(=O)=O +CC(c1ccc(F)cc1)N(C)C(=O)C1CCC(=O)N1 +C#CCSc1nc(CCC)nc2c1c(=O)n(C)c(=O)n2C +COc1cc(OC)c(NC(=O)NCc2nc(C)sc2C)cc1F +O=C(CNC(=O)Cc1ccc(F)cc1)NCCN1CCOCC1 +CCOc1ccc(-c2cc(C(=O)Nc3cccc(C)n3)no2)cc1 +OCCc1nnc(Cc2ccc(Oc3ccccc3)cc2)o1 +CCn1c(=O)n(CC)c2cc(C(O)C3CCCCC3)ccc21 +CCC(C)(C)NC(=O)c1ccc(NC(=O)NCc2cccnc2)cc1 +CCNC(=O)c1cc(Cl)ccc1NC(=O)COc1ccccc1C +CCOCC1CCN(C(=O)Cc2ccc(F)c(F)c2)C1 +C#Cc1cccc(NC(=O)NCc2ccc(OCCC)c(OC)c2)c1 +CC1Nc2cc3c(cc2N(CCC#N)C1=O)CCCC3 +CC(C)N(Cc1cccnc1)C(=O)C1COc2ccc(F)cc2C1 +N#CC(C(=O)CSc1nc2ccccc2o1)c1ccccc1 +CN(C)c1nc(CNC(=O)c2cccc(-c3ccoc3)c2)cs1 +Cc1ccc(OCC(=O)Nc2nnc(C3CC3)s2)cc1 +CCCOC(=O)N(c1ccc(Cl)cc1)S(C)(=O)=O +Cc1noc(C)c1Cn1cc(S(=O)(=O)N(C)C)ccc1=O +COCCCn1c(=O)c(C#N)c(C)c2c(N)n[nH]c21 +COC(=O)CN1CCN(C(=O)c2ccc(C)s2)CC1 +O=C1CC(C(=O)N2CCOCC2)CN1CCc1ccc(F)cc1 +FC(F)Oc1ccc(CNCCc2nccs2)cc1 +CCCn1cc(NC(=O)c2sc(N(C)C)nc2C)cn1 +CC(C)(C)OC(=O)N1CCN(C(=O)Nc2ccccc2F)CC1 +CCC(C)NC(=O)Cn1c(S(C)(=O)=O)nc2ccccc21 +O=C(Nc1ccc(NC(=O)C2CCCO2)cc1)c1ccc(F)cc1 +CC(C)C(=O)Nc1ccccc1S(=O)(=O)C(F)F +COc1cccc(C(=O)NC(CO)c2ccccc2)c1F +Cc1ccc(C(=O)Nc2ccc3oc(=O)ccc3c2)cn1 +Cc1ccc(NC(=O)NCCC(C)C)cc1-n1cnnn1 +Nc1ccc(Cl)cc1C(=O)NCC1CCCCO1 +CC(C)(C(=O)N1CCNC(=O)CC1)c1cccc(Cl)c1 +O=C1N(Cc2ccc(F)cc2)c2ccccc2C12OCCCCO2 +CCCNC(=O)CNC(=O)NCc1nc2ccccc2s1 +CCc1noc(CC)c1CNC(=O)C(NC(C)=O)C1CCCC1 +COc1ccc(C(=O)NCc2cccc(NC(C)=O)c2)nn1 +Clc1ccc(N2CCC(Nc3ccc4nnnn4n3)C2)cc1 +Cc1ccccc1S(=O)(=O)N1CCOc2c(N)cccc21 +Cc1nc(CNC(=O)CSc2nncn2C(C)C)c(C)s1 +CN(C)c1ncccc1NC(=O)c1ccc(F)cc1 +CCc1cccc(C)c1NC(=O)NC1COc2c(cccc2OC)C1 +CC(Cc1cccs1)C(=O)NCCc1nc[nH]n1 +COc1ccccc1CNC(=O)C(C)Oc1ccccc1OC +CC1COC(c2ccccc2)CN1CC(=O)NCc1ccco1 +NC(=O)C1CCN(C(=O)CCc2nc(Cc3ccccc3)no2)CC1 +CS(=O)(=O)N1CCC(Oc2ccc(-n3cnnn3)cc2)CC1 +CCCn1nccc1NC(=O)c1cnn(C(C)(C)C)c1 +COc1cccc(OC)c1Oc1c(F)cc(N)cc1F +COc1ccccc1N1CCN(C(=O)NC(C)Cn2cccn2)CC1 +CCCc1nnc(NCc2cc3cc(OC)ccc3o2)o1 +O=C(CSc1nnc(-c2ccccc2)o1)N1CCCC1 +CC(C)OCCC(=O)N1CCCCc2ccccc21 +CCC(NC(=O)NCCNC(=O)c1cccnc1)c1cccs1 +COc1ccc(F)c(NC(=O)NCc2ncc[nH]2)c1 +COCCCC(=O)Nc1ccc(-c2cc[nH]n2)cc1 +O=C1NCC2(CCN(S(=O)(=O)C3CC3)CC2)c2ccccc21 +CC(=O)c1ccc(C(=O)NCc2coc(-c3ccc(C)cc3)n2)cc1 +CC1(C)CCCN1C(=O)c1cccc(C#CCO)c1 +C=CCN(C(=O)c1cnn(C)c1N)c1nc2c(s1)CCCC2 +C=CCNC(=O)C(C)Sc1nnc2n1CCCCC2 +O=C(c1ccc2c(c1)[nH]c(=O)n2C1CCCC1)N1CCCS1(=O)=O +Cc1noc(C)c1C(=O)NC(CC(C)C)c1ccccc1 +Cc1ccc(F)cc1NC(=O)C(C)Sc1ncn[nH]1 +Cc1cccc(OC(=O)Cc2csc(NC(=O)c3ccco3)n2)c1 +Cc1ccc(NC(=O)c2ccc(C(C)C)nc2N)cc1 +C=CCOC(C)C(=O)Nc1cnn(CC(N)=O)c1 +O=C(NC1(CCO)CCC1)c1c(O)cc(F)cc1F +Cc1c(Cl)ccc(S(=O)(=O)NCc2ccco2)c1Cl +Cc1cc(=O)c2cccc(C(=O)Nc3ccc(F)cc3)c2[nH]1 +CCOC1CCCN(C(=O)c2cc(Cl)c[nH]2)C1 +Cn1cc(CN2CCN(CC(O)COc3ccc(F)cc3)CC2)cn1 +c1ccc2c(c1)CC(Cc1cc(N3CCCC3)cnn1)CCO2 +OCC1(Nc2ccccc2)CCN(c2ncc(Cl)cn2)CC1 +Cc1noc(COCC(=O)Nc2cnc(C(C)(C)C)nc2)n1 +COC(=O)c1nn(Cc2ccc3c(c2)OCO3)c(=O)c2ccccc12 +Cc1ccc(NC(=O)NCc2scnc2C)cc1S(C)(=O)=O +CC(OC(=O)c1cccc(OCC(=O)N(C)C)c1)c1cccc(F)c1 +Cc1cc2nnn(CCOc3ccccc3N)c2cc1C +O=C(CCn1c(=O)oc2cc(Cl)ccc21)NCC1CCCO1 +COc1ccc(CNc2cnn(CC(F)F)c2)cc1C#N +CC(=O)c1cccc(-c2nc(C3CCOC3)no2)c1 +Cc1ccc2cc(CCC(=O)NCc3ccccn3)c(=O)[nH]c2c1 +C#CCOC(=O)c1cc(Br)ccc1F +CC(=O)N(C)C1CCN(C(=O)NCC2(c3ccccc3F)CC2)CC1 +COc1cccc(-c2n[nH]cc2C(=O)NCc2cn3cccnc3n2)c1 +CC(=O)Nc1cccc(NC(=O)N2CC(C)OC(C)C2)c1C +CC(=O)N(c1ccc(O)c2ccccc12)S(=O)(=O)c1ccccc1 +COc1ccc(CO)cc1OCc1cccc(Cl)c1 +CN(CC(O)C1CC1)C(=O)c1csc(-c2ccc3c(c2)OCO3)n1 +CCc1nnc(SCCC(=O)NCc2ccccc2)n1N +CN(C)S(=O)(=O)N1CCCC(CCc2cccc(F)c2)C1 +CC(C)CC1NCCc2cccc(OC(F)F)c21 +COc1ccc(C)cc1CN1CCN(C(=O)c2cc(Cl)c[nH]2)CC1 +CC(O)C1CCCCN1S(=O)(=O)c1cccc2cccnc12 +O=C(Nc1ccccc1C(F)(F)F)c1ccc(-n2cnnn2)cc1 +COCCNC(=O)C1CC(=O)N(c2ccccc2Cl)C1 +COc1ccccc1NC(=O)Cc1noc(-c2ccc(C(N)=O)o2)n1 +Cn1ccnc1C(NC(=O)Cc1cccs1)c1cccc(F)c1 +CC(C)N1CC(C(=O)N2CCC(Nc3ccccc3)CC2)CC1=O +COc1ccc(C(O)CNCc2ccc(C)cc2)cc1Cl +CNC(=O)c1cccc(NC(=O)COC(=O)c2ccc(CO)cc2)c1 +CCCn1ncc(-c2cc(OC)ccc2OC)c(CO)c1=O +Cc1cc(C)c(C2CC(=O)NCc3nc(N(C)C)sc32)cc1C +COc1ccc(C(=O)N(CCc2cccs2)C2CC2)cc1F +COC(=O)c1ccccc1S(=O)(=O)Nc1cccc(C#N)c1 +CCCc1cc(C(=O)NCc2cnc(C)cn2)no1 +Cc1cc(NC(=O)CCCc2nc(-c3cccs3)no2)ccn1 +CC(C)C(=O)NCc1nn(C)c(=O)c2ccccc12 +O=C(CCn1nc(C(=O)Nc2ccccc2)ccc1=O)NC1CC1 +C=CCNC(=O)NC1C2COC(O2)C(Sc2ccccc2)C1O +N#CCCn1c(Cc2ccccc2)nc2ccc(F)cc21 +Cc1noc(CC2CC3CN(C(=O)c4ccc(C)o4)CC3O2)n1 +COc1cc2c(cc1Br)CCNC2CO +Cc1ccc(S(=O)(=O)N(C)Cc2cc(F)cc3cccnc23)cc1 +Cn1cnc(CNC(=O)c2conc2-c2ccc(Cl)cc2)n1 +CC(C)(Oc1ccc(Cl)cc1Cl)C(=O)N1CCOCC1 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1ccc(N2CCCC2=O)cc1 +COCCCN1CC2(CCN(C(=O)c3cc[nH]c3)CC2)CC1=O +CCSc1ccc(C(=O)OC(C)COC)cn1 +OCc1cc(F)cc(CO)c1OCc1csc(-c2ccccn2)n1 +CNC(=O)c1sc(NC2CCOCC2)nc1C +CN(C)C(=O)c1ccc(CNC(=O)Nn2cnc3ccccc32)cc1 +CC1CC(=O)Nc2cccc(Br)c2O1 +O=C(NCCc1ccccc1)C1Cc2ccccc2O1 +CC1OCCC1C(=O)NCC(O)Cc1ccc(F)cc1F +CCC1CCC(NC(=O)C2CCCN(S(C)(=O)=O)C2)CC1 +C=CCN1C(=O)CCCC12CCCN(C(=O)c1ccc(C)c(C)c1)C2 +Cc1c(-c2nnnn2-c2ccc(Cl)cc2)cnn1-c1ccccc1 +CCOc1cc(CNC(=O)C2CC2c2ccccc2F)ccc1OC +Cc1cc(C)n(CC2CCCN2C(=O)c2cccc(C(N)=O)c2)n1 +COc1cccc(NC(=O)NCc2cnc(C)s2)c1 +COc1ccc2c(O)cc(C(=O)N3CCOCC3)cc2c1 +C=CCOc1cccc(NC(=O)c2csc(C)n2)c1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3cccc(O)c3)cc2)n1 +Cc1ccccc1-c1nnn(CC(=O)N(Cc2ccccc2)C2CC2)n1 +O=C(CCNc1ncccn1)Nc1ccc2c(c1)OCCO2 +COC(=O)CC(NC(=O)c1n[nH]c(=O)[nH]1)c1cccs1 +COCCCN(C)C(=O)Nc1ccc(Oc2cccnc2)c(C)c1 +CCc1ccccc1OCc1nc(C)c(CO)s1 +COc1ccccc1Oc1ccc(NC(=O)c2ccccn2)cc1F +COCc1ccc(C(=O)Nc2ccccc2C(C)C)o1 +CCCCN(CCOC)C(=O)Nc1cc(F)cc(F)c1 +O=C(NCCCn1cccn1)c1sc2ccccc2c1Cl +NC(=O)c1ncn2c(C(=O)N3CCOCC3)cc(-c3ccco3)nc12 +COCCNc1nc(-c2cccn(C(C)C)c2=O)cs1 +O=c1cc(-c2ccc(Br)cc2)[nH]c(=O)[nH]1 +Cc1csc(CCCNCc2cc(=O)c3cc(F)ccc3[nH]2)n1 +COC(=O)C1(NCc2ccn(-c3ccccc3)n2)CCCC1 +CCCCOc1ccc(OCC(=O)N2CCN(C)CC2)cc1 +Cn1cc(NC(=O)CNC(=O)c2ccsc2)ccc1=O +Cc1cc(N(C)CC(C)O)ccc1Br +Cc1ccc(OCCCC(=O)Nc2cccc(N)c2)cc1C +CCn1nc(C)c(NC(=O)CCCc2cc(F)ccc2F)c1C +COc1ccc(-c2nc3sc(C)c(C)n3c2CC#N)cc1 +CC(=O)NC1CCCN(C(=O)NCCc2c(F)cccc2F)C1 +COc1ccc(-c2n[nH]c(SC(C)C(N)=O)n2)c(OC)c1 +COc1cccc(C(=O)NCC(C)(C)N2CCOCC2)c1OC +O=C(NCc1cccc(O)c1)c1ccc2c(c1)OCCO2 +CCOCCOC(=O)c1cc2c(C)nn(-c3ccc(F)cc3)c2s1 +CCS(=O)(=O)N1CCCc2cc(C(=O)NCCCOC)ccc21 +Cc1cc(F)ccc1N1CCCC(NC(=O)C2CC2)C1 +COc1ccc(-c2cc(CC(=O)NC(C)C)no2)cc1OC +CNC(=O)c1sc(NCc2ccccc2OC)nc1C +CN(CCc1nc2ccccc2[nH]1)C(=O)C1COc2ccccc2C1 +Cc1ccc(-c2nnn(CC(=O)N(C)c3ccc(F)cc3)n2)cc1 +O=C(COc1ccccc1F)NCCN1CCOCC1 +CN(C(=O)c1cccc(NCc2nc(C3CC3)no2)c1)c1ccccc1 +CNC(=O)c1cccc(OC(=O)c2cc(C)sc2C)c1 +COc1cc(OC)cc(C(=O)Nc2cc(C)nn2C)c1 +COc1cc(C#N)ccc1OCC(=O)NC1CCCCC1 +CN(C(=O)C1CC1)c1ccccc1C(=O)Nc1ccc(C(N)=O)cc1 +COC(C)(C)c1noc(C(=O)c2cnn(-c3ccccc3)c2)n1 +COc1cccc(C(=O)OCc2ccccc2F)c1O +CNC(=O)C1CCC(NC(=O)c2ccc(F)cc2)CC1 +COc1cc(O)cc2c1CCNC2C1CCCN1C(C)=O +O=C(NCc1cn2ccccc2n1)c1ccc2c(c1)OCO2 +CC(=O)Nc1cc(NCc2cnc(C(C)C)s2)ccc1F +CCC1COCCN1C(=O)COc1ccccc1N +COC(=O)c1ccc2c(c1)CCN2C(=O)C1CCCO1 +Cc1cc(NC(=O)CN2CCc3ccccc32)on1 +CNC(=O)Cc1ccccc1NC(=O)c1cc(C)ccc1C +Cc1occc1C(=O)Nc1cccc(C(=O)Nc2nccs2)c1C +CCCNS(=O)(=O)c1cc(-c2ccc(=O)n(CC)n2)cs1 +COc1ccc(CCCn2cc(N)cn2)c(Cl)c1 +O=C(NC1CCCCC1)c1cc2n(n1)CCS2 +CN(C(=O)c1cnc2c(c1)c(=O)n(C)c(=O)n2C)C1CCCC1 +Cc1oc(-c2ccc3c(c2)OCCO3)nc1CC#N +CC(C)CC(C)N(C)C(=O)CCc1cccc(N)c1 +CCc1nnc(SC(C)C(=O)Nc2ccc(F)cc2)n1N +Cc1n[nH]c(-c2cccc(CNC(=O)c3ccc[nH]c3=O)c2)n1 +CC(C)(C)c1ccc(C(=O)Nc2ccc3[nH]c(=O)c(=O)[nH]c3c2)cc1 +O=C(OCCn1cc(Br)ccc1=O)c1cccnc1 +CC(C)N(C(=O)Cn1c(CCO)nc2ccccc21)C(C)C +CCC1Oc2cc(O)ccc2N(CC(=O)N2CCCC2)C1=O +O=C(CN1CCc2ccccc2C1)NCCc1ccccc1 +Cc1cccc(C)c1OCC(O)CN1CCOC2CCCCC21 +O=C(c1ccccn1)N1CCC2(CC1)Cc1ccccc1CNC2=O +Cc1n[nH]c(C)c1CCN(C)C(=O)c1ccc(C2CCCO2)s1 +Cc1occc1C(=O)Nc1ccc(F)cc1OCC1CC1 +O=C(Nc1ccccn1)C12CC3CC(C1)CC(n1cncn1)(C3)C2 +COc1cc(C)nc(N2CCN(C(=O)Cn3cccnc3=O)CC2)n1 +CS(=O)(=O)N1CCN(C(=O)CNc2cccc(Cl)c2F)CC1 +Cc1cc(C)n(-c2cccc(C(=O)Nc3ncccc3C)c2)n1 +CCOC1CC(NC(=O)c2ccc(OCC(F)F)nc2)C12CCC2 +O=C(c1ccccc1C(F)(F)F)N1CCOCC1 +CNS(=O)(=O)c1cc(Cl)c(Cl)cc1C(=O)OC +Nc1c(Cl)ccc2c1CCN(CCN1CCOCC1)C2 +CCc1nc(C2CCCN(S(=O)(=O)c3cccc(F)c3)C2)no1 +Cc1ccc(OCC(=O)Nc2ccc(C)c(C)c2)nc1 +COCC(=O)Nc1cc(N2CCCC2=O)ccc1Cl +COC(=O)c1c(NC(=O)CO)sc2c1CCC(C)C2 +CN(Cc1nnc2ccccn12)c1ncc(C#N)cc1Cl +O=C(Nc1cccnc1)c1ccc(OC(=O)C2CCOCC2)cc1 +O=C(NCc1ccc(N2CCCCC2=O)cc1)c1cn2cccnc2n1 +CC(=O)NCC1CCN(c2cccc(F)n2)CC1 +O=C(NCCN1CCc2ccccc21)c1cnc(-c2cccnc2)nc1 +CCn1cc(C(=O)Nc2cccnc2-n2cccn2)c2ccccc21 +COc1cc(CNC(=O)c2ccccc2F)ccc1OC(F)F +Cc1cc(C)c(N(C)C(=O)c2cccc(N)c2)c(C)c1 +Cc1nc(C2CCCN(C(=O)C(C)OCC3CCCO3)C2)no1 +CCN(CC)C(=O)CCC(=O)N1CC=C(c2ccc(Cl)cc2)CC1 +O=C(Cc1ccccc1)NCCC(=O)Nc1cc(F)ccc1F +Cc1ccc(CN(C)C(=O)Cn2cnc(C#N)n2)c(C)c1 +C#CCn1nc(CO)cc1-c1ccc(Br)cc1 +CN(Cc1cccnc1)C(=O)C1CCCN1C(=O)CC(C)(C)C +CC(=O)Nc1ccc(C)cc1OCc1csc(-c2ncccn2)n1 +Cc1oc(C)c(C(=O)N2CC(C)C(N3CCOCC3)C2)c1C +Cc1ccc(N2CC(NC(=O)CCc3ccccc3)CC2=O)cc1 +O=C(NCCC1=CCCCC1)C1CC(=O)N(CC2CC2)C1 +CC1(C)Cc2cc(CN3CCOC4(CCOCC4)C3)ccc2O1 +CC(C)C1Oc2ccc(CO)cc2N(C(C)C)C1=O +CCCCn1c(=O)c2c(nc3n(CC(C)C)c(C)cn23)n(C)c1=O +N#Cc1ccc(NC(=O)CCCn2cncn2)cc1 +Cc1ccnc2nc(C(=O)N(C)Cc3ccc(OC(F)F)cc3)nn12 +CC(=O)Nc1cccc(NCc2cccc(Br)c2)c1 +Cc1ccc(N2CCCC3(CCN(C(=O)C4CCCO4)C3)C2)nn1 +Cc1cccc2c(=O)c(C#N)cn(CC(=O)OC(C)C)c12 +Cc1nc2ccccc2nc1CN1CCc2nn(C)c(=O)cc2C1 +Cc1nc2c(C)cccn2c(=O)c1NC(=O)c1cccc(F)c1 +CC(C(=O)NCc1ccccc1Cl)N1CCOCC1 +COc1ccc(C(=O)COc2ccc(C)cc2N)cc1OC +CC(C)N(Cc1cnn(C)c1)C(=O)c1ccc(Cn2cncn2)cc1 +COc1ccc(C(=O)CCCC(=O)N2CCCC2)cc1Cl +Cc1noc(C2CN(Cc3ccc(Cl)c(Cl)c3)C2)n1 +CC(CO)NC(=O)C1CC(=O)N(c2cccc3ccccc23)C1 +COc1c(C(=O)NCc2ccco2)nnn1Cc1ccc(C)cc1 +Cn1c(SCC(=O)N2CCCCCC2)nnc1-c1ccco1 +CCCCN(CC)C(=O)c1c[nH]nc1-c1ccc(OC)cc1 +CCS(=O)(=O)c1ccccc1NCc1sccc1C +COc1ccc(OCC(=O)NC(C#N)C(C)(C)C)cc1 +Cc1cnc2n(c1=O)CC(C(=O)Nc1cc(F)ccc1F)CS2 +Cc1noc(C)c1CNC(=O)NCCc1ccccc1C(F)(F)F +CC1CCCC(OC(=O)CCn2c(=O)[nH]c(=O)c3ccccc32)C1 +CC(=O)Nc1cc(NC(=O)C2CC3CCC2C3)ccc1F +CCCCN(C)C(=O)CN1C(=O)CCCc2ccccc21 +COC(=O)C(C)CN(C)C(=O)c1ccc(-c2ccsc2)nc1C +COCc1cccc(C(=O)N(CC(F)(F)F)c2ccccn2)c1 +CN(C)C(=O)CNc1ccc(C(=O)N2CCCC2)cc1 +O=C(Cn1ccc(=O)c2cccc(F)c21)Nc1cccnc1 +CCCC(=O)N1CCC(C(=O)Nc2ccc(F)cc2F)CC1 +COCc1ccccc1C(=O)NCC(O)c1ccc2ccccc2c1 +CC(C)NC(=O)CNc1cccc(NC(=O)c2ccco2)c1 +N#Cc1c(F)cccc1Oc1cccc2cccnc12 +O=C(NCc1cccc(Cl)c1)C1CCC(Cn2cnnn2)CC1 +Cc1cc(NC(=O)NCc2cnn(C)c2C)ccc1OC(C)C +CCCN(CC1CC1)C(=O)Cn1c(C2CCCO2)cc2cccnc21 +O=C(NCc1ccnc2ccccc12)c1ccc(O)cc1F +CS(=O)(=O)Nc1ccc(CC2CCCCC2)cc1O +Cn1ccc2c(C(=O)OC3C(=O)OCC3(C)C)cccc21 +O=c1[nH]nc(CN(CCO)CCN2CCOCC2)[nH]1 +COC(=O)c1cc(-c2cc(C)cc(C)c2OC)nn1C +CC(CCc1ccccc1)NC(=O)c1nc(-c2cccnc2)no1 +CNC(=O)c1ccc(Oc2ccc(Cl)cc2)nc1 +O=C(Nc1cccc(-c2nnnn2C2CC2)c1)c1cnns1 +O=C(Cn1cnnn1)N1CCN(c2ccc(-n3cncn3)nn2)CC1 +O=C(CCSc1ccccn1)Nc1cccnc1 +Cc1nn(C)c(C)c1OCC(=O)N1CCc2ccc(Cl)cc2C1 +CC(=O)NCCNC(=O)N1CCC(Oc2c(C)cccc2C)CC1 +CC(C)(C)c1nnnn1CCS(=O)(=O)c1ccccc1 +CC(=O)N1CCc2cc(NCc3cccc(C#N)c3)ccc21 +Cc1cc(C)c(-c2cn3cccnc3n2)c(C)c1N +COC(=O)c1cccc(Cn2ccnc2-c2cccnc2)c1 +CCc1cc(=O)n(CC(=O)NCCOC)c(-n2nc(C)cc2C)n1 +CCCN(Cc1ccsc1)C(=O)c1cccc(OC)c1OC +COc1c2c(cc3oc(=O)ccc13)OC(C)(C)C=C2 +COC(=O)c1cc(OC)c(OC)cc1NC(=O)c1ccc(=O)[nH]n1 +Cc1ccc(C(=O)OCc2nnc(-c3ccccc3)o2)c(C)n1 +CCCCNC(=O)Nc1cc(=O)n(C)c(=O)n1C +COc1cc2c(cc1CNC(=O)CCCc1ccccn1)OC(C)C2 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)Cc1noc2ccccc12 +CC(C)N(CCO)C(=O)c1cc(Cl)cc(Cl)c1 +CC1(C)CCC(CC(=O)NCc2csc(=O)[nH]2)CC1 +COCCCNC(=O)Cc1noc2c(Cl)cc(N)cc12 +Cc1cnc(SCc2cccc(C(=O)NCc3ccco3)c2)nc1 +COCCOc1ccccc1NC(=O)N1CCCC(CO)C1 +CC1CCC(NC(=O)COc2ccc3c(c2)CCC3)CC1 +CCCCN(CC(N)=O)S(=O)(=O)N1CCC(C)CC1 +O=C(c1ccc(F)cc1Cl)N1CCN(Cc2cncs2)CC1 +COC1C2CCC1CN(C(=O)Cn1c(=O)ccc3ccccc31)C2 +NC(=O)c1cc(-c2csc(NC(=O)CC3CC4CCC3C4)n2)c[nH]1 +Cn1cc(COC(=O)c2ccc3ccccc3n2)cn1 +CC(C)n1cnnc1CN1CC(c2ccccc2)CC1=O +COc1ccc(C(=O)N(C)C(C)c2cccc(Cl)c2)cc1OC +CN(c1nc2ncccc2[nH]1)C1CCN(C(=O)OC(C)(C)C)CC1 +Cc1cccc(OC(C)C(=O)Nn2c(C)nc3sccc3c2=O)c1 +COc1cc(C)sc1C(=O)N1CCC2(CC1)OCCCC2O +N#Cc1cnn2c(C(F)(F)F)cc(C(F)(F)F)nc12 +CC(C)c1noc(-c2ccnc(-n3cnc(C(=O)NC4CC4)c3)c2)n1 +CC(O)CN1CCN(Cc2nnc(Cc3ccccc3)o2)CC1C +COc1ccc(C2CCCN2c2ncnc3c2cnn3C)c(OC)c1 +CCCc1[nH]nc(C(=O)NCC(C)COC)c1N +COc1ccc(NC(=O)c2ccc(N(C)C)nc2)cn1 +c1cc(-c2cn[nH]c2)cc(-c2nc(C3CC3)n[nH]2)c1 +CC(=O)Nc1ccc2nc(NC(=O)c3ccn(C)n3)sc2c1 +COC(=O)CCN(C(=O)c1cc(C)nn1C)c1ccccc1C +COc1cc(CNC(=O)Nc2cccc(C)c2)ccn1 +COc1ccc(C(CC(=O)N2CCNC(=O)C2)c2ccccc2)cc1 +CC1(C)CN(CC(F)(F)F)CCN1C(=O)N1CCOCC1 +CN(C)c1ccc(-c2ccc3nc(N)nn3c2)cc1 +CC1CC(=O)Nc2c1c(NC(=O)c1ccccc1)nn2C +Cc1nc(C)c(CNC(=O)c2cccc(-c3ccoc3)c2)s1 +COc1cccc(CNc2cc(C)nc3ncnn23)c1 +CCNC(=O)c1cnc(COc2ccc(C)cc2C)nc1N +Nc1ccccc1S(=O)Cc1cc(Br)cs1 +CCOC(=O)C1CC(=O)N(c2cccc(N3CCCC3)c2)C1 +CC(=O)c1c[nH]c(C(=O)N(C)Cc2ccoc2C)c1 +CC1CC(=O)Nc2cc(S(=O)(=O)N(C)CCO)ccc2O1 +Cc1cc(C)n(CC(=O)Nc2ccc(C)c(C(=O)NC(C)C)c2)n1 +O=C(COc1cccc(Cl)c1)NCCN1CCOCC1 +COC(C)c1cccc(NC(=O)c2cc3c([nH]c2=O)CCCC3)c1 +CC(=O)c1cccc(OCC(=O)Nc2c(F)cccc2F)c1 +N#Cc1ccc(CSc2nnc(-c3cccnc3)n2N)cc1 +CCOC(=O)Nc1ccc(NC(=O)c2sccc2C2CC2)cc1 +CCC1=C(C(=O)OC)C(c2cccc(OC)c2)n2ncnc2N1 +CC(CO)NC(=O)NCCc1ccc(-n2cccn2)cc1 +COc1ccc(OCC(=O)N2CC(C)c3ccccc32)cc1 +Cc1ccc2ncc(C(=O)Nc3cc(NC(=O)C4CC4)ccc3C)n2c1 +CCc1nc(COC(=O)c2cnn(-c3ccccc3)n2)cs1 +CC(C)(C)c1n[nH]cc1CNc1cnn(-c2ccccc2)c1 +Cc1cc(C(=O)NCC2(C)CCCC2)cc(S(N)(=O)=O)c1C +O=C(NCc1ccc2c(c1)OCO2)N1CCC(n2cccc2)CC1 +Cc1ccc(C)c(N2CCN(C(=O)CC(C)C)C(C)C2=O)c1 +COc1ccccc1OS(=O)(=O)c1cc(F)cc(F)c1 +COc1ccc2c(c1)CC(CNC(=O)c1ccccc1Cl)O2 +Cc1nc(NCc2nncn2CCc2ccccc2)c2cnn(C)c2n1 +OCC1CCCN1c1cc(NCCc2c[nH]c3ccccc23)ncn1 +CCN(Cc1cnn(C)c1)C(=O)c1cc(Br)ccc1O +COC(=O)C(C)CNC(=O)Nc1ccc(F)c(F)c1 +O=C(NCCNS(=O)(=O)c1ccccc1Br)C1CC1 +N#Cc1ccc(CNc2ccc(F)c(F)c2)c(F)c1 +CCS(=O)(=O)c1ccc(N2CCCCC2C)cc1N +O=C(Nc1cccc(-c2ccn[nH]2)c1)C1CCOC1 +O=C(C1CC1)N1CCN(Cc2c(F)cccc2Cl)CC1 +CC(C)CCN(CCC(C)C)C(=O)c1ccc2c(c1)OCC(=O)N2 +O=C(NCc1ccc(-n2cnc3ccccc32)nc1)c1ccc[nH]c1=O +CS(=O)(=O)NCCNS(=O)(=O)c1ccccc1C(F)(F)F +CCn1cc(CN(C)C(=O)c2cc(N)nn2C)c(C)n1 +CN(C)C(=O)Cc1ccc(NC(=O)c2cccc(C#N)c2)cc1 +CC(NC(=O)NCc1ccccn1)c1ccc2c(c1)CCC(=O)N2 +CC1(NS(=O)(=O)c2cccc(F)c2C#N)Cc2ccccc2C1 +Cc1cc(C(=O)NCCCn2cccn2)c(C)n1-c1nccs1 +NC(=O)COc1cccc(C(=O)N2CCN(c3ncccn3)CC2)c1 +CC(=O)Nc1ccc(C(=O)NCCCn2cnc3ccccc32)s1 +CC(=O)Nc1ccc(-c2csc(C(N)c3ccc(F)cc3)n2)cc1 +O=C(CSc1nnc2ccc(-c3cccnc3)nn12)N1CCCC1 +COc1cc(OC)cc(Oc2cc(C)c(N)c(C)n2)c1 +CCCCCOC1NC(N)=Nc2nc3ccccc3n21 +CCOC(=O)c1ccc(S(=O)(=O)Nc2cn[nH]c2)o1 +CC(C)N(C)S(=O)(=O)c1ccc(F)c(C(=O)N2CCCC2)c1 +COC(=O)CCNC(=O)N1CC(C)Sc2ccccc21 +COc1cc(C)c(C(=O)NC(C#N)c2ccc(Cl)cc2)cc1OC +COc1ccnc(N2CCN(c3ncccn3)CC2)n1 +Cc1cnc(C(=O)NC(C)c2ccccc2OC(C)C)cn1 +COCCCCSc1nnnn1C1CCOCC1 +Cc1ccc2c(Cn3c(C)nn(C(C)(C)C)c3=O)cc(=O)oc2c1 +COCCN(C(=O)c1cnn(-c2ccccc2)c1)c1ccc(C#N)cc1 +CC(C(=O)NCCc1cc(Cl)cc(Cl)c1)n1cncn1 +CCc1ccc(C2COCCN2CC2=CCCOC2)o1 +Cc1ccc(S(=O)(=O)NCC(C)C#N)cc1C +COc1cc(SC)ccc1C(=O)Nc1ccnc2[nH]ncc12 +O=C(NCc1cn(-c2ccccc2)nn1)c1ccccc1 +CC(C)C(NS(=O)(=O)C(C)C)c1ccc(F)cc1 +N#CC1c2ccccc2CCN1C(=O)c1ccccc1 +CS(=O)(=O)NCc1cccc(C(=O)NC2CC2)c1 +Cc1cc(C(=O)NC2CCc3c(O)cccc32)c(C)o1 +COc1cc(CN(C)C(C)=O)c(SC)cc1OC +Cc1cccc(CN2CC(F)C(OCc3nc4ncccc4[nH]3)C2)n1 +COc1ccc(Cl)cc1NC(=O)c1ccc(C)c(N)c1 +Cn1cccc1C(=O)Nc1ccc(Br)cc1 +O=C(C1CCOC1)N1CCC2(C=Cc3ccccc32)CC1 +O=C(CSc1nnc(-c2cccnc2)o1)Nc1ccccn1 +Cc1cc2n(n1)CCCN2CC(=O)Nc1cc(Cl)ccc1C +O=C(Nc1cccnc1)c1ccc2c(n1)NCCS2 +COC(=O)CC(C)(C)CC(=O)N1CC(c2ccsc2)CC1C +COc1cc2c(cc1OC)CN(c1ccc3cc[nH]c3n1)CC2 +C#CCNS(=O)(=O)c1ccc(C(=O)OC2CCCC2)cc1 +Cc1ccc(CNC(=O)Cn2nc(C(C)(C)C)ccc2=O)cc1F +COc1ccccc1-c1nnc(C2CCN(c3ncccn3)C2)o1 +CS(=O)(=O)c1cccc(C(=O)NCc2cccnc2)c1 +CN(Cc1ccoc1)C(=O)C1CC(=O)N(Cc2ccncc2)C1 +O=C(CC1CCCCC1)N1CCN(c2nnc3ccccn23)CC1 +Cc1c(CN2CCCC(c3nncn3C(C)C)C2)cnn1C +COc1ccccc1C#CCNC(=O)c1cc2ccccc2[nH]1 +CC(OC(=O)c1ccc(F)cc1N)C(=O)NC1CCCCC1 +COc1ccc(-c2csc(N3CCCC3)n2)cc1OC +CCOC(=O)C1CCN(C(=O)CN(C)C(=O)Cc2ccc[nH]2)CC1 +O=C(CC1COCC2CN(c3ncccn3)CC12)N1CCCC1 +COc1cc(OC)c(OC)cc1CN1CC(C)OC(C)C1 +CCOC(=O)CNC(=O)C(N)c1cccc(F)c1 +c1cc(-n2cnc3cc4c(cc32)OCCO4)ccn1 +CC1CCCC(OC(=O)CCC(=O)Nc2ccccc2)C1 +CCc1ccc(C(=O)CNS(=O)(=O)N(C)C)cc1 +CC(C)CC(=O)N1CCC(Oc2nncc3ccccc23)CC1 +Cc1ccc(S(=O)(=O)Nc2c(C)cccc2C)cc1C(N)=O +CC(N(C)S(=O)(=O)c1ccccc1N)C(C)(C)C +CC(=O)Nc1cccc(NC(=O)N(C)CCCOc2ccccc2)c1 +O=C(CCCCC(=O)Nc1nccs1)Nc1nccs1 +CCOc1ccccc1NC(=O)c1ccc(F)cc1F +CCc1nn2cc(-c3ccc(OC(C)C)cc3)nc2s1 +Cc1ccsc1C(=O)NC1CCc2cc(F)ccc21 +CCC(C(=O)N1CCC(OCC(N)=O)C1)c1ccccc1 +COc1ccc(-c2n[nH]cc2C(=O)NCCNC(C)=O)cc1 +O=C(NC1CCc2ccccc21)c1ccc(-c2ccco2)[nH]c1=O +CCS(=O)(=O)c1ccc(O)c(NC(=O)c2ccccc2)c1 +COCCn1cc(NC(=O)NCc2ccsc2)cn1 +CC1CCc2nc(NC(=O)c3ccn(C)n3)sc2C1 +CC(c1ccccc1)S(=O)(=O)c1ccc2c(c1)OCCCO2 +CN(c1ccccc1)c1ccccc1C(=O)N1CCNC(=O)C1 +O=C(CCn1ccnc1)Cc1ccc(Br)cc1 +CN1CCSc2ccc(S(=O)(=O)NC3CCCC3)cc21 +Cc1noc(C)c1CCC(=O)Nc1nc(-c2ccccc2F)n[nH]1 +CCCS(=O)(=O)N1CCCCC1C(=O)Nc1cc(CC)n[nH]1 +COC(=O)c1ccc(CN(C)C(=O)CCc2ccco2)cc1 +CC(C)Cc1nc2oc3c(=O)n(C)cnc3c2c2c1CCC2 +Cc1ccc(NC(=O)C(C)Nc2cnn(CC(F)F)c2)c(F)c1 +Cc1c(Cl)cccc1NC(=O)C(C)CC(N)=O +CCCCNC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +COc1ccc(C2CN(c3nc(C)cnc3C)CC2NC(C)=O)cc1 +OCCCc1nc2ccccc2n1C1CCCCC1 +Cc1nc(CNS(=O)(=O)c2c(C)nn(C)c2C)oc1C +CC(NC(=O)NCC(=O)N(C)C)c1ccc(Cl)cc1Cl +Cc1ccc(-c2nc(CNC(C)Cc3c(C)noc3C)co2)cc1 +C=CCNC(=O)CN1CCOC(c2cccc(Br)c2)C1 +CC(O)CN1CCN(C(=O)CC(NC(N)=O)c2cccs2)CC1 +CS(=O)(=O)NC1CC2CC1N(C(=O)c1ccc3c(c1)OCO3)C2 +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c1C +CC(C)c1nc(C(C)Nc2ncc(S(N)(=O)=O)s2)cs1 +Cc1cnn(CCC(=O)N2CCC(OCc3ccccc3C)CC2)c1 +CC(C)n1cnnc1SCC(=O)N(C)CCC#N +CCOC(=O)c1cccc(NC(=O)c2ccn(CC)n2)c1 +Cc1ccc(-n2cnnn2)cc1NCc1nc(-c2ccccc2C)no1 +O=C(Cn1cnnn1)Nc1ccc(OC(F)F)c(Cl)c1 +Cc1cc(C(=O)Nc2cc(C(F)(F)F)ccc2Cl)no1 +Cc1ccc(-c2cc(-c3ccccc3)nc(N)n2)o1 +Cc1cc(C)c(-c2nc(-c3ccncc3)no2)c(=O)[nH]1 +CC(C)NC(=O)C1CC2CN(C(=O)Cc3ccccn3)CC2C1 +COCC(=O)N1CCN(c2cccc(C)c2C)C(=O)C1C +COc1cccc(Cc2cn3cc(C#N)ccc3n2)c1 +CCOc1ccc(C(C)Nc2ncnc3c2cnn3CCC#N)cc1 +Cn1c(-c2ccccc2)nc2cc(CCO)ccc21 +COC(=O)CCNC(=O)Cn1nnc(-c2cccs2)n1 +CC(CNC(=O)NCC1CN2CCCCC2CO1)Cn1cccn1 +COC(=O)c1ccccc1NC(=O)c1cnn(C)c1N +COC(=O)c1cc(-c2cc(C)cc(Cl)c2OC)on1 +COCCn1cc(NC(=O)CCC2CCCCO2)ccc1=O +Cn1c(=O)ccn(CC(=O)OCc2ccccc2Cl)c1=O +C#CCC(NS(=O)(=O)c1cccc(C)c1Cl)C(N)=O +N#Cc1ccc(Cn2nncc2-c2ccc(F)c(F)c2)cc1 +Cc1ccc(NC(=O)NCCc2cccc(F)c2)cc1-n1cnnn1 +O=C(Cn1c(=O)oc2ccccc21)N1CC(c2nc3ccccc3[nH]2)C1 +CC(CNC(=O)C1CN(C)CCO1)c1nc(-c2ccccc2)no1 +CCNC(=O)NC1(C(=O)N(C)CCOC)CCCC1 +Cn1cnc(CNC(=O)C2CCCN2C(=O)Cc2cccs2)n1 +CC1=NC(C(=O)NC2CC2)=C(C)C1S(=O)(=O)N1CCC(C)CC1 +O=C(CCCNC(=O)C1CC1)NCc1cccc2ccccc12 +CCN(CC(C)C#N)C(=O)c1ccc(C(=O)N(C)C)cc1 +COc1ccc(C2CC(O)=Nc3c2cnn3C)cc1O +NC(=O)Nc1cc(Br)cnc1OCC(F)(F)F +COCC(O)CN(C)C(=O)Nc1ccc(-n2nc(C)cc2C)nc1 +COCCCNC(=O)c1cc2c([nH]c1=O)CC(C)CC2=O +CC(C)n1c(=O)c2sccc2n(Cc2ccc(C#N)cc2)c1=O +c1cncc(CN2CCc3nc4ncccc4cc3C2)c1 +Nc1c(Br)ccc2c(NCCCO)nccc12 +CCS(=O)(=O)c1ccc(S(=O)(=O)N2CCC(C)CC2C)cc1 +COc1cccc(CC(=O)OCC(=O)Nc2cc(F)cc(F)c2)c1 +CCCNC(=O)CNc1cc(-n2cnnn2)ccc1C +COc1ccc(CN2C(=O)C3(OCCO3)c3ccccc32)cc1 +CC(C)Oc1ccc(NC(=O)c2cn(C)n3cccc3c2=O)cc1 +O=c1nc2n(c(=O)[nH]1)-c1cc(F)ccc1CS2 +CN(C(=O)Cn1cnc2ncccc2c1=O)C1CCCCC1 +CCn1c(-c2cc(OC)ccc2OC)ccc(C#N)c1=O +O=C(NC1CCN(c2ccccc2)C1=O)c1c(F)cccc1F +CC(CCNS(C)(=O)=O)c1cccc(C(F)(F)F)c1 +CN(C)c1oc(C=Cc2ccc(F)cc2)nc1C#N +O=C(CCNC(=O)c1csc(-c2nc[nH]n2)n1)Nc1ccccn1 +N#Cc1c(NC(=O)Cc2c[nH]c3ccccc23)sc2c1CCC2 +CCN(CC)S(=O)(=O)c1ccc(=O)n(Cc2csc(C)n2)c1 +Cc1cc(C)n(CCCNC(=O)CN(C)S(C)(=O)=O)n1 +Cc1ccc(C)c(S(=O)(=O)NCC(C)(O)C(=O)OC(C)(C)C)c1 +COc1ccccc1C(C)N(C)C(=O)NCCN1CCOCC1 +CC(=O)Nc1cccc(NC(=O)NCCCc2c(C)noc2C)c1C +NS(=O)(=O)c1ccc(NC(=O)COc2ncccn2)cc1 +CC(C)CCNC(=O)c1ccc2nc(N3CCOCC3)sc2c1 +CSc1ccc(C(=O)Nc2ncn(Cc3cccnc3)n2)o1 +O=C(COc1ccc(F)c(Cl)c1)OCC1CCCO1 +CCCCNC(=O)CC1CCN(C(=O)Nc2ccccc2)CC1 +CCCN1CCN(C(=O)CN2Cc3ccccc3C2=O)CC1 +CC(c1cccs1)N(C)C(=O)c1cccc(C#CC(C)(C)O)c1 +CC(Oc1ccc(-c2nnco2)cc1)C(=O)NCCc1cccs1 +Cc1cccn(CCCC(=O)Nc2cccc(C#N)c2)c1=O +COC(=O)c1cccc(Nc2nc(C)c(CCO)c(=O)[nH]2)c1 +Nc1nccnc1C(=O)Nc1cc(Br)c[nH]c1=O +O=C(COC(=O)c1ccc(O)cc1O)c1ccc(Cl)cc1 +COc1cc(C)c(C(=O)Nc2cc(NC(C)=O)ccc2F)cc1OC +Cc1ccsc1-c1nccn1-c1ccc2c(c1)NC(=O)CO2 +Cc1cc(C(=O)N(Cc2ccccc2)Cc2cccc(C)n2)ncn1 +CS(=O)(=O)Nc1cccc(C(=O)N2CCC3CCCCC3C2)c1 +COc1ccc(C)cc1CN(C)S(=O)(=O)c1cn[nH]c1 +COc1ccc2c(c1)CN(C(=O)c1ccc(O)c(Cl)c1)CC2 +Fc1cccc(F)c1CNCc1ccncc1Cl +O=S(=O)(c1ccc(F)c(Cl)c1)N1CCC2(CC1)OCCCO2 +CCc1nc(CNc2cc(C)cc3cccnc23)cs1 +CCn1c(C)c(C(=O)N2CCCC2)c2cc(OC)ccc21 +COC(=O)C(C)NC(=O)c1cc2c(s1)-c1ccccc1CC2 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)Nc3cc(C)on3)ccc21 +C=CCOc1ccc(C(=O)NC(C)c2cccnc2)cc1OC +Nc1cccc(C(=O)COc2ccc(Cl)cc2)c1 +CC(C)(CC(=O)Nc1cccc(NS(N)(=O)=O)c1)c1ccccc1 +CCn1nc(C)c(Cl)c1C(=O)NCc1c(C)nn(C)c1C +c1ccc2c(N3CCC(c4ccn[nH]4)CC3)ncnc2c1 +Cc1ccc(C(=O)N2CCCC(C(=O)OCc3nc(C)no3)C2)cc1 +Cc1nc2ccc(NC(=O)c3ccc(-c4cscn4)cc3)cc2o1 +COc1ccc2[nH]cc(CCNC(=O)c3ccc4ccccc4n3)c2c1 +Cn1nnnc1-c1cccc(NC(=O)NC(CCO)C(C)(C)C)c1 +Cn1nccc1-c1nnc(NC(=O)c2ccc(C#N)cc2)o1 +Cc1cc(S(=O)(=O)n2ccnc2)c(Cl)cc1Cl +COCCn1c(C)cc(-c2ccc(C)cc2)c(C#N)c1=O +CCN(c1ccc(OC)cc1)S(=O)(=O)c1c[nH]c(C(=O)OC)c1 +Nc1ccc(Cl)c(C(=O)NC2CCCNC2=O)c1 +CNC(=O)CCCC(O)c1ccc(OC)c(F)c1 +O=C(c1ccn(-c2ccccc2Cl)n1)N(CC1CCOC1)C1CC1 +Cc1nc(C)n(C2CCCN(C(=O)c3sc(C(C)C)nc3C)C2)n1 +CCOC(=O)N1CCCC(C(=O)N(C)C(C)C)C1 +CC(=O)c1ccccc1OCCSc1nc(C2CCCC2)n[nH]1 +O=C(Cc1ccc(F)cc1)Nc1cc(-c2ccncc2)n[nH]1 +O=C(NCCc1ccccn1)N1CCN(c2cccs2)CC1 +Cc1cc(C)c(C(=O)NCC(C)(O)c2ccsc2)c(C)c1 +CC1(C(=O)NCc2nc3ccccc3[nH]2)Cc2ccccc2C(=O)O1 +Cc1ccc(C(CNc2ncccn2)N2CCOCC2)s1 +Cc1csc(=O)n1Cc1cc(F)cc2c1OCOC2 +Cc1ccc(C)c(S(=O)(=O)N2CCCC(C(=O)N(C)C)C2)c1 +CC(C)Oc1ccc(C(C#N)CC(=O)N2CCCC2)cc1 +Cc1ccccc1C(C)NC(=O)C1CCN(C(=O)C2CC2)CC1 +N#Cc1cccnc1NCc1ccc(Oc2ccccc2)nc1 +N#Cc1nc(COc2ccccc2)oc1N1CCC(C(N)=O)CC1 +Cc1ccc2nc(COC3CN(c4ncccn4)CC3F)[nH]c2c1 +COCCN(Cc1cc(=O)c2cc(F)ccc2[nH]1)CC1CC1 +O=C(Cc1nc(-c2cccc(F)c2)no1)Nc1ccc(F)cc1 +Cc1cc(-c2csc(Nc3ccccn3)n2)c(C)o1 +CCS(=O)(=O)N1CCC2OC(COc3cccnc3)CCC21 +CCN(C)C(=O)c1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1 +Cc1cc(Cl)ccc1NS(=O)c1ccc(N)cc1 +C=CCCCN(C)C(=O)CNC(=O)c1cccc(C)c1 +COC(=O)Nc1cccc(NC(=O)c2cc(C)ccc2C)c1 +CC(NC(=O)c1cc(-c2ccccc2Cl)on1)c1cccnc1 +Cc1nc2c(Nc3ccc(C#N)cc3)ncnc2[nH]1 +Cc1ccc(NC(=O)c2c(Br)cnn2C)cc1F +O=C(CNS(=O)(=O)c1ccc(F)c(C(F)(F)F)c1)NC1CC1 +CC(C)Oc1ccc2c(C(=O)N3CCC(=O)CC3)cc(=O)oc2c1 +CCc1onc(C)c1NC(=O)NCc1ccc(OC)nc1 +CCOC(=O)c1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1 +CC(NC(=O)NCC(O)c1cccc(F)c1)c1ccc(F)cc1 +CC(=O)N1Cc2ccccc2CC1C(=O)Nc1nnc(C2CC2)s1 +Cc1c(NC(=O)NC2c3ccccc3CC2O)cccc1OC(F)F +CC(C)c1nn2ccccc2c1C(=O)NCC(=O)NC1CCCC1 +Cc1cc(NC(=O)NC2CCCC2C)ccc1C(=O)N(C)C +CCC(CC)c1nnc(NC(=O)CC(C)C)s1 +Cc1cccc(NC(=O)COc2ccccc2F)c1 +CC(CC(=O)NCc1ccncc1)c1ccccc1 +COc1ccc(N(C)S(=O)(=O)c2ccc(C#N)cc2)cn1 +C#CCC(OC(=O)c1ccc(-n2cncn2)cc1)c1ccccn1 +C=CCNC1=NS(=O)(=O)c2cc(CCCC)ccc2N1 +Cn1cc(N2CCC3(CCN(C(=O)c4cccn4C)C3)C2=O)cn1 +Cc1ccc(-n2nnnc2NC2c3ccccc3CC2O)cc1 +CCC(CNC(=O)c1ccc(-n2cncn2)cc1)c1ccccc1 +Oc1ccccc1C1=Nc2ncnn2C(c2ccc(F)cc2)C1 +CCN1c2ncccc2C(=O)NC12CCN(C(=O)c1ccco1)CC2 +COCc1cc(C(=O)Nc2cccc(C(C)OC)c2)ccc1F +Cc1nc(CNC(=O)OC(C)(C)C)cc(C2CC2)n1 +CCc1nc(COC(=O)c2cc3cnn(C(C)C)c3nc2C)cs1 +Cc1nn(C)c2[nH]c(=O)c(CCC(=O)NCc3nncn3C)c(C)c12 +CCn1cnc2c1c(=O)n(CCOC)c(=O)n2-c1ccccc1C +CC(=O)Nc1cc(C(C)(C)C)nn1Cc1ccccc1 +COCC(=O)N1CCCN(C(=O)Nc2ccc(C(C)=O)cc2)CC1 +Cc1ccsc1CCNC(=O)c1cnc(N2CCCC2)nc1C +CCn1nc(C)c(NC(=O)N2CCOC(C)C2C)c1C +Cn1cc(C(=O)Nc2cnn(Cc3ccccc3)c2)c(C(F)(F)F)n1 +Cc1cc(Br)c2ncc3c(c2c1)OCCOC3=O +COc1cc(CNC(=O)Cc2cnn(-c3ccccc3)c2)ccn1 +COc1cccc(CNc2ccc3nnc(C(F)(F)F)n3n2)c1 +CN(C)S(=O)(=O)N1CCC(C(=O)c2cccs2)CC1 +CN(C)c1cccc(CNC(=O)CC(O)c2ccc(Cl)cc2)c1 +COc1cccc(S(=O)(=O)Cc2coc(-c3cccs3)n2)c1 +COCCNc1cc(-c2ccccc2)nc(-c2ccncc2)n1 +c1ccc(CCCSc2nnnn2Cc2ccco2)cc1 +CCCCN(Cc1ccccc1F)C(=O)Cc1cnc(N)[nH]c1=O +Cc1cccnc1NC(=O)Cn1c(C)cc2ccccc21 +CS(=O)c1ccccc1NC(=O)c1cnn(-c2ccc(F)cc2)n1 +CCCCN1CC(C(=O)N2CCN(C)CC2)CC1=O +O=C(NCc1ccccc1Cn1cccn1)c1cnns1 +CCNC(=O)c1ccc(CNC(=O)c2cc(C)n(C3CC3)c2C)cc1 +FC(F)(F)c1nnc2ccc(NCc3cc4ccccc4o3)nn12 +CC(NC(=O)CCCN1CCOC1=O)c1ccc(C(F)(F)F)cc1 +O=C(Nc1cnn(CC2CC2)c1)c1ccc(Cl)c(Cl)c1 +O=C(CNC(=O)C1(c2cccc(F)c2)CCC1)NC1CC1 +FC(F)(F)COc1nc(N2CCOCC2)nc(N2CCOCC2)n1 +COc1ccc(S(=O)(=O)Nc2ccc(C(C)=O)cc2)cc1F +COc1ccc(C(CC(=O)Nc2cccc(F)c2)NC(C)=O)cc1 +Cc1cnc2c(c1)N(S(=O)(=O)c1ccccc1Cl)CCO2 +O=C(Cn1ccc2ccccc21)NCCNC(=O)c1ccccc1O +CCC1CCCCC1OC(=O)c1ccc(OC)nn1 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1nc(-c2cccnc2)cs1 +CC(Cc1ccc(Cl)cc1)N(C)C(=O)c1cc(F)cc2[nH]cnc12 +Cc1nn(Cc2ccc(C(=O)NC3CC3)o2)c(C)c1Br +CSc1n[nH]c2ncnc(NCCCn3cnc4ccccc43)c12 +CCNc1ncc(C(=O)Nc2cnn(CC(F)(F)F)c2)s1 +CC(C)n1cc(C(=O)N2CCC(C)(O)C(C)(C)C2)cn1 +Cc1nc(C(=O)NCc2cnc3c(C)cccn23)cs1 +Cc1ccc(C)n1CCN1CCN(C(=O)c2ccc(F)cc2)CC1 +Cn1nc(C(=O)Oc2ccc(NC(=O)c3ccccc3)cc2)ccc1=O +CCOc1cccc(NCC(=O)NC(C)CC)c1 +O=C(CCn1cccn1)NCc1cccnc1Oc1ccccc1F +Nc1nc(SCC(O)COc2ccc3ccccc3c2)n[nH]1 +CC(C(=O)N1CCN(c2ccccc2)C(=O)C1)N1CCCC1=O +CNC(=O)C1CCCN1C(=O)c1cnn(C)c1C +Cc1cc(C(=O)CN2CCN(c3ccccc3O)CC2)c(C)[nH]1 +CS(=O)(=O)NCCCNC(=O)c1ccc(F)c(C(F)(F)F)c1 +O=C(c1cscn1)N1CCC2(CCCN(c3ncccn3)C2)C1 +CC(C)=CCN1C(=O)C2CCC1CN(C(=O)c1ccc(=O)[nH]c1)C2 +Cc1cc(C)nc(CN2CC(C)(c3ccccc3)CCC2=O)n1 +Cn1cc(CC2C(O)CCN2S(=O)(=O)c2cccs2)cn1 +CC(C)CCn1c(-c2nonc2N)nc2ccccc21 +Cc1nc(Cc2noc(COc3cccc(Cl)c3C)n2)no1 +Cc1cccc2c1cnn2CCC(=O)NCCn1cc(Cl)cn1 +CCn1cc(CNC(=O)c2noc3c2CC(C(C)(C)C)CC3)c(C)n1 +CCn1nc(C)c(NCc2cccc(-n3cccn3)c2)c1C +CCC(=O)Nc1ccc(NC(=O)c2cccs2)c(Cl)c1 +Cc1cc(C(N)=O)ccc1NC(=O)c1ccsc1 +Nc1c(-n2ccc(C3CC3)n2)ccc2scnc12 +O=C(CSc1nnc(C2CC2)n1Cc1ccco1)N1CCCC1 +O=C(c1cc(-n2cccn2)ccn1)N1CCc2cc(F)ccc2C1 +CC(C)CC(C#N)NC(=O)c1cccc(OCc2cccnc2)c1 +CN(Cc1cccc(C#N)c1)C(=O)NC1CCCc2ccccc21 +CC(C)c1ccc2nc(Cc3cccc(C(N)=O)c3)[nH]c(=O)c2c1 +Cc1cc(C(=O)Nc2nnc(CSc3ccccc3)o2)no1 +COc1cccc(NC(=O)NCC2CCC(=O)N2)c1 +OCc1ccc(CN2CCCC2c2nc(-c3ccc(F)cn3)no2)o1 +COC1CCC(CC(=O)N2CC(C)Sc3ccccc32)CC1 +CC1CCCC(CO)(Nc2cc(C(C)C)ncn2)C1 +Cc1ccc(C(C)NS(=O)(=O)c2cnc(N)nc2)o1 +COc1ccc(C(O)CNc2ccc(NC(C)=O)cc2)cc1 +CC(C)COc1ccc(C(O)CCN2CC(C)OC(C)C2)cc1 +COCCNC(=O)CN1CC(C)Nc2cc(Cl)ccc21 +COc1cccc(NC(=O)Cc2nnc(-c3ccsc3)o2)c1 +NC(=O)c1ccccc1NC(=O)c1ccc2nccnc2c1 +COc1ccc(C(=O)Nc2cccc(N)c2C)c(O)c1 +COc1ccc(S(=O)(=O)NCC2CCCO2)cc1 +C#Cc1cccc(NC(=O)c2cc(Cl)ccc2F)c1 +CC(C)n1cnc2cc(CNC(=O)c3nn(C)c4ccccc34)ccc21 +O=C(c1ccc(Cl)cc1)N1CCN(CCOc2ccccc2)CC1 +Cc1ncc(CNC(=O)N(C)Cc2ccccc2Cl)s1 +CC1CCCCN1C(=O)NCCC(=O)NCc1ccncc1 +CN(CCn1cnnc1)C(=O)Nc1cccc(C#Cc2ccccc2)c1 +Cc1ccc2ncc(C(=O)Nc3cccc(N4CCNC4=O)c3)n2c1 +COc1ccc(NC(C)=O)cc1OCc1ccc2ccccc2n1 +CC(C)S(=O)(=O)N1CC(c2nc(-c3ccco3)no2)C1 +Cc1cc(C(=O)N2CCc3nc(NC(=O)C4CCC4)sc3C2)no1 +CCN(CCC#N)C(=O)COc1cc2oc(=O)cc(C)c2cc1Cl +Cc1csc(NC(=O)CCn2c(=O)oc3ccccc32)n1 +CCOC(=O)c1cc(O)c2c(OC)cc(OC)cc2c1 +O=C(CCn1cncn1)Nc1cccn(Cc2ccccc2)c1=O +Cn1cc(Cl)c(C(=O)Nc2cnn(CC3CC3)c2)n1 +CCOC(=O)c1ncccc1NC(=O)C1Oc2ccccc2OC1C +Cc1noc(C2CCC3(CCN(C(=O)c4cscn4)CC3)O2)n1 +O=C1N2CCN(Cc3ccccc3F)CC2CN1C1CCOCC1 +O=C(Cc1ccc2c(c1)OCCO2)Nc1cccc(-n2cnnn2)c1 +COCCn1c(CNC(=O)c2ccc(C)cc2C)nc2ccccc21 +NS(=O)(=O)c1cccc(NCc2ccc(F)cc2F)c1 +NC(=O)c1ccc(NC(=O)COc2c(Cl)cccc2Cl)cc1 +Cc1cc(NC(=O)C(C)OCC2CCCO2)no1 +CN(C)C(=O)c1cc2cn(C3CCCC3)cc2s1 +COc1ccc(C(=O)Nc2ccc(-n3ccc(C)n3)cc2)c(OC)c1 +Fc1ccc(CNn2cnnc2SCc2ccc(F)cc2)cc1 +COc1ccc(Cl)cc1C(=O)N1CCCC1C(N)=O +CC(C)N1CCOC(c2noc(C=Cc3cccnc3)n2)C1 +COc1ccccc1OCC(=O)NC(C)c1ccc(F)cc1 +O=C(CCCn1c(=O)[nH]c2ccsc2c1=O)NC1CCCCC1 +Cc1cccc(CC(=O)NC2CCCN(Cc3ccccc3)C2=O)c1 +CN(C1CCCC1)S(=O)(=O)CCn1cnc2ccccc21 +CCCC(=O)Nc1cccc(NC(=O)N2CCC(C)CC2)c1 +CN(Cc1ccccn1)C(=O)NCC1(c2ccccc2)CC1 +Cc1c(-c2cccs2)nn(-c2ccccc2)c1N +CC(C(=O)NCc1ncc[nH]1)N(c1ccccc1)S(C)(=O)=O +FC(F)(F)c1ccccc1CNc1nccc(-c2ccccn2)n1 +COc1ccc2oc(C(=O)N3CCC(CC(N)=O)CC3)c(C)c2c1 +O=C(NCc1ccccc1)c1cc(-c2ccccc2Cl)[nH]n1 +Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)N1CCCC1 +O=C(CN1CCCC1=O)N1CCN(CCSc2ccccc2)CC1 +COc1ccc(-n2nc(C3CCCC3)nc2CCc2cnccn2)cc1 +Cc1cccc(C)c1NC(=O)COc1ccc(C#N)cc1Cl +Cc1cc(C(=O)Nc2nccs2)cc(S(N)(=O)=O)c1C +O=C(NCC(O)c1ccc(F)c(F)c1)c1ccc2[nH]cnc2c1 +Cc1nc(CNC(=O)NC(CCO)C(C)(C)C)oc1C +CC(=O)Nc1ccc(CNc2ccc(CN3CCCC3=O)cc2)cc1 +Cc1ccc2cnn(CCC(=O)Nc3ccn(CC#N)n3)c2c1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)Nc1cc(-c2cccs2)n[nH]1 +N#Cc1ccc(NC(=O)COc2ncnc3ccccc23)cc1Cl +O=C(Nc1cccnc1)N1CCC1c1ccc(Cl)cc1 +O=C(Nc1nncs1)c1ccc(C#CCO)cn1 +COc1cccc(CCC(=O)N2CCN(CC(=O)NC(C)C)CC2)c1 +CCOc1cc(NC(=O)C2(c3ccccc3)CCC2)ccc1OC +Cc1cc(C)n(C2CCN(S(=O)(=O)c3cccnc3)CC2)n1 +Nc1nccnc1C(=O)OCC(=O)Nc1ccccc1-c1ccccc1 +O=C(CNC(=O)C12CC3CC(CC(C3)C1)C2)OCC1CCCO1 +COCC(C)NC(=O)NCC1CCN(c2cccc(OC)c2)C1 +CCOc1ccc(F)c(C(=O)Nc2ccc3c(c2)NC(=O)CO3)c1F +CC(C)(C)NC(=O)c1cccc(NC(=O)C2CC3CCC2C3)c1 +C=CCOc1nc(C)c2c(c1C#N)CC(C)(C)OC2 +O=C(CCC1CCCO1)OCc1ccccc1Cl +Cc1ccc(-c2noc(Cc3c(C)nc(C)[nH]c3=O)n2)nn1 +CC(=O)Nc1c(Sc2ccccc2)nn(C)c1N +CCNS(=O)(=O)c1cc(C(C)(C)C)ccc1OC +Cc1ccn2c(=O)c(C(=O)NCCCOCC3CCOC3)cnc2c1 +COc1cccc(S(=O)(=O)CC(=O)Nc2cc(C(C)C)no2)c1 +Cc1ccc(C)c(-c2ccc(=O)n(CC(N)=O)n2)c1 +COCCNC(=O)C1CCCN(c2nc3c(F)cccc3s2)C1 +O=C(CN1CCN(C(=O)CC(F)(F)F)CC1)NCC1CCCCC1 +CN(CC(=O)Nc1ccc(-c2ccccc2)cc1)S(C)(=O)=O +Cc1ccccc1-c1nnn(Cc2noc(-c3ccsc3)n2)n1 +Cc1cc(C)n(CCC(=O)NCCc2ccc(Cl)cc2)n1 +COCC(=O)N1CCCN(S(=O)(=O)c2ccccc2)CC1 +Cc1ccc(C(=O)Nc2ccccc2OCCC(N)=O)cc1C +O=C(CC1CCCCC1)N1CCN(c2ncccn2)CC1 +COc1ccc(OC)c(CNc2cc(F)cc(F)c2)c1 +Cc1nc2ncccc2c(=O)n1CCNC(=O)c1ccc(F)cc1 +COc1ccccc1C(C)N(C)C(=O)c1scnc1C +Cc1[nH]ncc1C(=O)Nc1cc(Cl)cc(Br)c1O +COc1ccc(CNC(=O)c2cnc3scc(C)n3c2=O)cc1 +CCc1ccsc1C(=O)Nc1nc(C)c(C)s1 +COc1nc(OC)nc(-c2cccc3nc(C)ccc23)n1 +Cc1ccc2nc(NC(=O)c3ccc(-n4ccnc4)nn3)sc2c1 +CN(Cc1ccc(C(N)=O)cc1)C(=O)NCC1CCC1 +CCCC1CN(C(=O)C2Cc3cc(F)ccc3O2)CCO1 +O=C(NCc1ccc(F)cc1)c1cnc2sc3c(n2c1=O)CCC3 +COCc1nc(CNc2nccc(-c3cccnc3)n2)no1 +CCCCN(CC)C(=O)C1CN(S(=O)(=O)C2CC2)C1 +CCOc1ccccc1C(=O)NCC(=O)N(C)CCC#N +COC(=O)c1cc(-c2ccc(Cl)c(C)c2)on1 +CCCC1c2ccccc2CCN1C(=O)CNC(=O)NC +NC(=O)COc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCn1cnnc1CNC(=O)NCc1cccc(Cn2ccnc2)c1 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+CCCN(C)C(=O)c1ccc2nc(-c3ccccc3)cn2c1 +CNC(=O)NCC(=O)NC(C)c1ccc(OCc2cccnc2)cc1 +Cc1ccc(C(=O)Nc2ccc(C)n(CC(=O)NC(C)C)c2=O)cc1 +CC(C(=O)N1CCCC1)n1nc(C(F)(F)F)c(Cl)c1C1CC1 +CN(CCC(F)(F)F)C(=O)COc1ccc(F)cc1 +NC(=O)C1CN(Cc2cc(Cl)ccc2Br)CCO1 +COc1cc(OC)cc(C(=O)Nc2cccc(-c3noc(C)n3)c2)c1 +Cc1ncc2c(n1)CCCC2NC(=O)COc1ccc2ccccc2c1 +CC(NC(=O)c1ccco1)C(=O)Nc1ccc(F)c(C(N)=O)c1 +O=C(NCC1(c2cccc(F)c2)CCOCC1)NC1CC1 +CS(=O)(=O)N(Cc1ccc(Cl)cc1)c1cccc(N)c1 +CC1Oc2ccc(NC(=O)Cc3ccccc3F)cc2NC1=O +CC(C)NC(=O)c1cnc(N2CCOCC2)nc1N +NC(=O)c1ccc(NCCCc2cccs2)cc1 +O=C(NCc1ccccn1)Nc1ccc(F)c(C(F)(F)F)c1 +CN(C)C(=O)C1CCCN1C(=O)C1CC1c1c(F)cccc1Cl +CCOc1ccc(Cl)cc1CN(C)C(=O)CCc1ccncc1 +CCCOc1ccc(C(=O)Nc2ccc(N)cc2OC)cc1 +N#Cc1ccccc1CN1CC2CCC(C1)N(Cc1ccccc1)C2=O +COc1ccc(C2CC(C)N(Cc3nnc(C(C)C)o3)C2)cc1 +COC1COC2C(NC(=O)C3CCCCC3)COC12 +CCS(=O)(=O)N(C)CCCNC(=O)C1Cc2cc(F)ccc2O1 +Cc1nc(SCC(=O)Nc2ccc(C#N)cc2)nc(C)c1C +CC(=O)N1C2CCC1c1cnc3cc(C)nn3c1C2 +Cc1nn(C)c2sc(C(=O)Nc3ccccn3)cc12 +CCn1nccc1C(=O)Nc1cnn(Cc2cccc(Cl)c2)c1 +CN(Cc1cnc2ccc(C#N)cn12)CC1CCCCO1 +O=C(c1ccc2nncn2c1)N1CCCC1Cc1ccccc1Cl +O=C(OCn1nnc2ccccc2c1=O)c1cc2c(s1)CCC2 +Cc1n[nH]c(C)c1SCC(=O)Nc1cccc(F)c1 +COc1ccc(CN(C)C(=O)CNC(=O)c2cc(C)oc2C)cc1 +CCN1CC2(CCCN(c3ncc(OC)cn3)C2)CCC1=O +CCc1nnc(N(C)CCc2scnc2C)o1 +CCN(CC)C(=O)COc1ccc(C(F)(F)F)cc1 +CC1OCCN(Cc2ccc(S(C)=O)cc2)C1C +CCc1c(C#N)nnn1-c1ccc(Cl)c(Cl)c1 +Cc1cccc2c(=O)n(CC(=O)NCCc3cccc(O)c3)cnc12 +COCCNC(=O)CNC(=O)C1CC1c1cccc2ccccc12 +CC(OC(=O)c1cc2c(s1)CCCCC2)C(N)=O +Nc1c(C(=O)Nc2c(F)cccc2F)oc2cccnc12 +O=C1CCC(C(=O)NCC#CCOc2cccnc2)N1 +CCCN(CC1CC1)C(=O)c1ccc(=O)n(Cc2ccccc2)n1 +CCOCCSc1nc2ccsc2c(=O)n1C +Cc1sc(C(=O)NCCC(=O)NC(C)C)cc1-c1ccc(F)cc1 +CNc1nc(C(=O)N(Cc2ccco2)C(C)C(C)C)cs1 +O=S(=O)(NCCO)c1ccccc1C(F)(F)F +Cc1nnc(CN2CCN(Cc3nnc(C)o3)C(C)C2)o1 +COCC(NC(=O)c1cc(-c2ccc(Cl)cc2)n[nH]1)C(N)=O +CN(C)C(=O)CN(C)C(=O)c1ccc(Cn2cccn2)cc1 +O=C1NCC2(CCN(C(=O)c3ccc4cccc(Cl)c4n3)CC2)O1 +COCc1c(C(=O)N(C)Cc2cc(C)on2)sc2cccc(F)c12 +COCCN(CC(C)C)C(=O)Nc1cccc(N)c1 +CS(=O)(=O)N1CCCN(C(=O)CNC(=O)c2cccs2)CC1 +CCOCC(=O)N1CCC2(CCOCC2NS(C)(=O)=O)CC1 +COc1nccnc1NCc1cccc(Cn2cccn2)c1 +Cc1cccc(NC(=O)COC(=O)Cc2ccc(F)c(F)c2)c1 +Cc1c(N)cccc1S(=O)(=O)N1CCC(C)CC1C +COc1ccc(NC(=O)NCC(C)N2CCOCC2)c(Cl)c1 +O=S(=O)(c1cccc(Cl)c1F)N1CCN(CC2CC2)CC1 +O=C(Nc1cc(F)ccc1F)c1ccnc(-c2ccsc2)c1 +O=C(NCCc1ccccc1)c1ccc2c(c1)C(=O)c1cnccc1-2 +NC(=O)C(OC(=O)c1cc2ccccc2o1)c1ccccc1 +COCCN(C)C(=O)c1cc(S(C)(=O)=O)ccc1Cl +Cc1cc(C(=O)C(C#N)c2nc3ccccc3[nH]2)c2c(C)nn(C)c2n1 +Cc1cnccc1C1NCCc2ccc(C)c(C)c21 +CCOCC1CCCN(C(=O)c2csc(-c3ccoc3)n2)C1 +Cc1cc(=O)c(OCC(=O)Nc2cccnc2)c[nH]1 +CN(C)C(=O)C(Cc1cccnc1)c1cccc(N)c1 +O=C(Nc1ccc(Cl)cn1)C1CCN(C(=O)c2ccsc2)CC1 +COCc1ccc(C(=O)NCCNC(=O)C(C)C)cc1 +Nc1cccnc1Sc1nnnn1-c1ccccc1 +COCCN(Cc1cccnc1)C(=O)NCc1c(C)cc(C)cc1C +COc1ccc(-c2nc(CC(C)C)nn2-c2ccccn2)cc1O +COc1ccc2oc(C)c(C(=O)N3CCCC(C(=O)N(C)C)C3)c2c1 +CC(C)n1cnnc1SCC(=O)Nc1ccn(C)n1 +COc1ccc(OC)c(C(=O)Nc2ccc(C(=O)NC3CC3)cc2)c1 +OCc1cn(-c2ccc(F)cc2)nc1-c1ccccc1 +COC(=O)CN(Cc1cnc(-c2cccnc2)s1)C(C)C +COCC(=O)N1CCC(c2nnc(-c3ccncc3)o2)C1 +CNc1snc(C)c1C(=O)N1CCN(c2cc(C#N)ccn2)CC1 +O=C(NCc1ccccc1OCC1CC1)c1cc2cccnn2c1 +Cc1ccc(N2CCCC3(COCCN(c4cnccn4)C3)C2)nn1 +COc1ccccc1OCC(=O)N1CC(c2nc3ccccc3[nH]2)C1 +Cc1cn2c(CN(C)C(=O)c3cc(C(N)=O)cs3)c(C)nc2s1 +CCCC1CN(C(=O)c2c[nH]nc2-c2ccc(OC)cc2)CCO1 +CN(CCn1nc2ccccn2c1=O)Cc1nccn1C(F)F +Cc1cccc(OCCc2nc(C)c(CCO)c(=O)[nH]2)c1 +CC(C)C(C(=O)NCC(O)Cc1ccccc1)N1CCCC1=O +CCOC(CC)C(=O)Nc1nc(C(C)C)cs1 +CCNC(=O)c1ccc(NC(=O)C(CC)Oc2ccccc2)cc1 +Oc1cc(F)c2c(c1)C(c1cc(F)ccc1F)NCC2 +Cc1nc(CC(=O)N(C(C)C)C2CCC2)cs1 +Cn1cnnc1-c1cccc(NC(=O)CC2CCCCC2)c1 +Cc1occc1C(=O)NCc1cnc(OCC(C)C)c(Cl)c1 +CC=CCc1nnc(C(=O)N(C)Cc2ccccc2C(F)(F)F)o1 +Cc1ccccc1CNc1ccccc1C(=O)NC1CC1 +Cc1cc(C)cc(C(=O)NCCCSc2nnc(C)s2)c1 +COCc1nc2cc(OC)c(OC)cc2n1CC(C)C#N +CNC(=O)c1cnc(-c2cccc(OC)c2)nc1N +Cc1cc(C(O)CCNS(=O)(=O)c2c(F)cccc2F)c(C)o1 +COC(=O)c1c(NC(=O)c2ccccc2Cl)csc1C +Cc1ccc2cccc(C(=O)Nc3ccn(-c4ccccc4)n3)c2n1 +CC(C)C1CCc2ccccc2N1C(=O)c1ccc(C#N)cn1 +COc1cc(C(=O)Nc2ccc3sccc3c2)cc(OC)c1OC +CCOC(C)C(=O)N(C)Cc1nc2ccccc2s1 +Cc1cc(C(=O)OCCn2nc3ccccn3c2=O)c(C)n1C(C)C +CCc1nc2ccccc2c(C(=O)OC2CCOC2=O)c1C +O=c1c(Cl)c(Cl)cnn1-c1ccc(C(F)(F)F)cn1 +COc1ccc(C)cc1C(C)NCCN1CCOCC1 +COc1ccc(C(=O)Nc2cnccc2C)c(OC)c1OC +Cc1ccc(Cn2nc(C(=O)NCc3ccncc3)ccc2=O)cc1 +CNC(=O)c1cccc(NC(=O)COC(=O)c2cccc(OC)c2)c1 +COc1ccc2cc(NC(=O)c3ccnn3C)cnc2c1 +CCC(C(=O)N1CCC2(CC1)OCCO2)c1ccccc1 +Cc1nc(C(C)(C)NCc2ccc(C#N)cc2)sc1C +Cc1ccccc1NC(=O)c1ccc(CNS(C)(=O)=O)cc1 +Cc1ccsc1CCNC(=O)CN1CCOC1=O +CN(Cc1ccccn1)C(=O)NCCc1ccccn1 +COc1cc2c(cc1OC)CN(C(=O)COc1cccc(C)c1)CC2 +COc1ccccc1C(C)NC(=O)Nc1ccccc1 +CC1CC1C(=O)Nc1ccc(C(=O)OCC(=O)N2CCCC2)cc1 +CCC(CCO)NC(=O)Nc1ccc(F)c(-n2nnnc2C)c1 +O=C(NCCNC(=O)c1ccccc1O)Nc1ccc(F)cc1 +COc1ccc(-c2cc(-c3ccco3)c3c(N)ncnc3n2)c(OC)c1 +CC1CN(CCC(=O)c2cccc(N)c2)CC(C)O1 +COc1ccc(CNC(=O)c2cccc(N(C)C)c2)c(OC)c1OC +OCc1cnn(-c2ccccc2F)c1C(F)(F)F +Cc1cccc(C2CC2C(=O)OCCOC(N)=O)c1 +O=C1CCC2C(CCN2S(=O)(=O)C2CC2)N1CC1CC1 +Cn1nnnc1-c1cccc(NC(=O)CCn2ccc3ccccc32)c1 +CNc1nc2c(s1)C(c1cc(F)ccc1F)CC(O)=N2 +COCCCN(C)C(=O)c1c(C)[nH]c2ccccc12 +CC(C)c1ccccc1NC(=O)NCc1ccc(C(=O)N(C)C)cc1 +CC(C)Nc1ccnc(-c2ccc3c(c2)OCO3)n1 +Cn1c(N)nnc1SCCCS(=O)(=O)c1ccc(F)cc1 +COc1ccc2c(c1)C(C(=O)NC1(CO)CCCCCC1)CC(=O)N2 +COc1cc(C)c(C(=O)N(C)CCc2ccccn2)cc1OC +CC(C)CNC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +Cc1noc(NC(=O)c2ccc(OCc3ccccc3)nc2)n1 +O=C(C1CCCO1)N1CCc2cc(Cl)cc(Cl)c2C1 +Cc1ccc(NC(=O)Cn2nnc(C(N)=O)c2C)cc1C +O=C(NCCCn1ccnc1)c1cc(Cl)ccc1O +O=C(NCc1ccccc1F)Nc1cnn(CCO)c1 +Cc1ccc(-c2nc(C#N)c(NCC(C)N3CCOCC3)o2)cc1 +CCOC(=O)c1csc(NC(=O)Cc2cccc(OC)c2)n1 +CC(=O)c1ccc(C)cc1OCC(=O)N1CCCC1c1cccs1 +CC(O)(CNC(=O)NC1CC=CC1)c1ccccc1Cl +CC1(C)CC2CC(C)(CN2S(=O)(=O)c2cncc(N)c2)C1 +O=C(OCc1nnc(-c2ccccc2Cl)o1)C1CC1c1ccco1 +CCNC(=O)CNC(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1 +O=C(Nc1cnn(CC2CCCO2)c1)Nc1ccc(F)c(F)c1F +O=C(NCc1ccc(Oc2cccnc2)c(F)c1)N(CCO)C1CC1 +Cc1nc(NC(=O)c2c(-c3ccccc3Cl)noc2C)sc1C +O=C(NCC1(c2cccs2)CC1)c1ccc(F)cc1 +C=CCCOC(C)C(=O)Nc1ccc(C)c2cn[nH]c12 +Cc1ccc(OCCCC(=O)N2CCCC(c3cc(C)[nH]n3)C2)cc1 +COC(=O)C(C)Oc1ccc(CN2C(C)COCC2C)cc1 +COc1cccc(C(N)=O)c1OCc1ccc(F)cc1 +CCc1oc(-c2ccncc2)cc1-c1csc(NC)n1 +O=C(c1ccccc1)N1CCC(C(O)c2ccccc2)CC1 +Cc1noc(CNC(=O)C2CSc3ncc(C)c(=O)n3C2)n1 +O=C(OCCn1cccn1)c1cnn2c(-c3cccs3)ccnc12 +Cc1cc(C)cc(N(C)C(=O)c2ccnc(N(C)C)c2)c1 +Cc1ccc(CNC(=O)NC2CCC(=O)N(C)C2)c(OCC2CC2)c1 +CCC(=O)NCCC1CCc2ccc3c(c21)CCO3 +CC(=O)N1CCNC(c2ccc(C(F)(F)F)cc2)C1 +Cc1ccc(C)c(CC(=O)Nc2c(C(N)=O)oc3ccccc23)c1 +COCC(=O)Nc1ccc(NC(=O)c2ccc[nH]c2=O)cc1 +COc1ccc(C)cc1C(C)Nc1cc(C)nc2ncnn12 +O=C(C1CCCCC1)N1CCN(Cc2cc(F)cc(F)c2)CC1 +NC(=O)c1ccc(-c2cc(NCCO)ncn2)cc1 +Cc1nn(C)c(C)c1CC(=O)Oc1ccc2ccccc2c1 +CCOC(=O)C(C)Sc1nnnn1-c1ccc(C)c(C)c1 +O=C(NCCc1csc(-n2cccn2)n1)Nc1c(F)cccc1F +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccc(OC)c(C)c1 +Cn1nnnc1SCC(=O)c1ccc(NS(C)(=O)=O)cc1 +CCC(C)(C)NC(=O)Nc1cc(F)c(OC)cc1OC +CC(C)c1nc(-c2nccn2CCCn2ccnc2)co1 +O=C(Cn1ccnc1-c1ccccc1)N1CC2C3CCC(O3)C2C1 +COCCNC(=O)CNc1ncnc2ccsc12 +O=C1CCN(Cc2ccc(F)cc2Cl)CCN1 +Cc1ccc(C(NC(=O)CCNC(=O)c2ccsc2)C2CC2)cc1 +Cc1cccnc1Nc1ncnc(Oc2cccnc2)c1N 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+CC(C)Sc1nc2c(c(=O)n1C)SC(C)C2 +CCOc1ccc(C(C)NC(=O)NCc2nnc3ccccn23)cc1 +Cc1nn(C)cc1C(=O)NCc1ccnc(OC2CCC2)c1 +COCC(C)NC(=O)c1cc(Br)cn1C +COc1ccc(C(=O)NCCCN2CCCCCC2=O)c(O)c1 +CN1C(=O)CCc2cc(S(=O)(=O)NCc3cccs3)ccc21 +COC(=O)C1(NC(=O)c2nn(C)c(=O)c3ccccc23)CCCCC1 +CC(C)(C)OC(=O)N1CCCC(Oc2ccncn2)C1 +CC1(C)NC(=O)Cn2cc(-c3ccc(Cl)cc3)nc21 +CC1(C)CN(CCc2nc(-c3ccccc3)no2)CCO1 +Nc1nc(CN2CCn3c(nnc3C3CC3)C2)nc2ccccc12 +CCCCNc1nc2c(c(=O)n(C)c(=O)n2C)n1CC(O)CO +CCN(C(=O)CCn1ccccc1=O)c1ccc(C)cc1C +C#CCNC(=O)c1cc(-c2cccc(OC)c2)nn1C +CC(C)CC1CCCCCN1C(=O)Cn1ccc(=O)[nH]c1=O +FC(F)(F)Oc1ccccc1CNc1cn[nH]c1 +CCc1cccc(C)c1NC(=O)Cn1c(-c2cccs2)noc1=O +CC(CNC(=O)NCCCO)c1ccc(F)cc1F +COc1ccc(CCC(=O)NC(C)(C)C)cc1OC +CCCNC(=O)C(C)(C)S(=O)(=O)c1ccc(Br)cc1 +COc1cc(C2CNC(=O)N2C)c(OC)cc1C +CCOC(=O)N1CCCC(C(=O)Nc2ccccc2C(=O)C(C)C)C1 +CCC(C)(C)NC(=O)CSc1nc(Cc2cccs2)n[nH]1 +COC(=O)C1CCN(S(=O)(=O)c2ccc(OC)c(Cl)c2)CC1 +Cc1cc(NC(=O)NCC(O)COc2cccc3ccccc23)no1 +Cc1nnc(CN2CCC(C(=O)NCCO)CC2)n1C +CCc1ncc(C(=O)Nc2cccc3ccccc23)c(N)n1 +CCCC(=O)NCC(=O)c1ccc(OC)c(Cl)c1 +CCCOC(=O)c1cccc(Cn2cc(N)ccc2=O)c1 +C=CCNC(=O)CN1CCN(c2ccc3nnc(CC)n3n2)CC1 +CCCNC(=O)CCc1nc(-c2ccccc2Cl)no1 +N#Cc1ccc(Oc2ccc(S(N)(=O)=O)cc2)cc1 +COc1cccc(C(=O)NCc2cccc3cccnc23)c1F +CCCn1nnnc1CNc1ccccc1Cl +Cc1nc(-c2ccc(OCC(=O)NCC3CCC3)cc2)cs1 +COC(C)C(=O)Nc1ccc(CNC(N)=O)cc1 +CCCCS(=O)(=O)N1CCN(c2cc(N(C)C)nc(C)n2)CC1 +Cn1cc(-c2nc(C(=O)NC3CC4CCC3(C)C4(C)C)cs2)cn1 +CCC(C)n1ncc(C(=O)N(C)CCc2ccccn2)c1C1CC1 +O=S(=O)(Cc1c(Cl)cccc1Cl)Nc1cn[nH]c1 +CNC(=O)c1cccc(OC(=O)c2cc(-c3ccccc3)no2)c1 +O=C(NCC(=O)N1CCOC2CCCCC21)c1cccc(Cl)c1 +CCOc1ccc(NC(=O)c2ncoc2C)cc1CO +COc1ccc(Cl)cc1-c1ccc(C#N)c(C)n1 +Cc1ccc(OCCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C +CC(NC(=O)N1CCC(C(N)=O)C1)c1ccccc1C(F)(F)F +Cc1cnc(C(=O)Nc2cccc(N3CCNC3=O)c2)cn1 +CCC1c2ccsc2CCN1C(=O)NCCc1cnn(C)c1 +CNS(=O)(=O)c1ccc(NC(=O)c2ccccc2)c(F)c1 +CCc1ccccc1NC(=O)c1cc(C(N)=O)cn1C +CC(C)OCCC(=O)NC1CCCOc2ccccc21 +Cc1cc(C)n(-c2c(N3CCOCC3)c(=O)c2=O)n1 +CCn1c(NC(=O)c2ccc3c(c2)OCCO3)nc2ccccc21 +COc1ccc(-n2c(C)nnc2SCC(=O)NC2CC2)cc1 +CC(=O)NC1CCCN(CC(=O)c2cc(C)n(CCC(C)C)c2C)C1 +O=C(CCC(=O)N1CCOC(c2ccc(F)cc2)C1)NC1CCCC1 +CC1CCCN(C(=O)NCc2ccnn2C)CC1 +COCC(=O)N1CC(S(=O)(=O)c2ccc(F)cc2)C1 +C=CCn1nnnc1SC(C)C(=O)c1ccc(OC)cc1 +Cn1cc(C2NCCc3ccc4cc(O)ccc4c32)cn1 +CCN(CCC#N)C(=O)c1ccc(C(=O)c2cc[nH]c2)cc1 +Cc1nc2cc(NC(=O)NCC(C)(C)c3ccncc3)ccc2o1 +CCC(CC)n1ncc(C(=O)Nc2ccc(C(C)=O)c(C)c2)c1C +O=c1c2ccccc2ncn1Cc1cc(-c2cccs2)on1 +CC(NC(=O)c1ccccc1-n1cnnn1)c1ccc(F)cc1F +Cc1ccc(NC(=O)N2CCN(C(=O)N(C)C)CC2)c(C)c1 +Cc1ccc(N(C)C(=O)CCNC(=O)C(C)(C)C)c(C)c1 +C=CCNC(=O)NCc1ccc(OC2CCCC2)nc1 +CCNC(=O)c1ccc(CNC(=O)c2ccc3c(c2)OCO3)cc1 +CCOc1ccccc1NC(=O)c1cccc(NC(=O)C(C)C)c1 +COC(=O)c1ccccc1NC(=O)C(C)n1cccn1 +N#Cc1ccc(OCCNc2ccccc2C(=O)NC2CC2)cc1 +O=C(c1sccc1-c1ccccc1)N1CCn2c(cccc2=O)C1 +O=C(NCc1ccccc1F)c1noc(-c2ccc3c(c2)OCO3)n1 +COC(=O)CN(C(=O)c1cc(C(C)C)n(C(C)(C)C)n1)C(C)C +CCCCn1ncnc1CCc1nc(-c2ccccc2F)no1 +C=CCNC(=O)c1ccc(-c2ccccc2OC)nc1N +COCC(=O)Nc1ccc2nc(C3CCCCC3)[nH]c2c1 +c1ccc(Cc2nnc(CN3CCOC(Cn4cccn4)C3)o2)cc1 +CCc1ccc(S(=O)(=O)NCc2ccccc2OC)cc1 +CC(C)(C)OC(=O)N1CCCN(Cc2n[nH]c(=O)[nH]2)c2ccccc21 +Cc1ccc(CNC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)n1C +Nc1cccc2c1NC(CC(=O)N1CCCC1)CN2 +Cc1onc(-c2ccccc2Cl)c1C(=O)Nc1ccccc1O +COc1ccc(Sc2ccc(NC(=O)C3CCC(=O)N3)cc2)cc1 +CN(Cc1[nH]nc2c1CCC2)C(=O)CCNC(=O)c1ccc(F)cc1 +CCCn1cnnc1CNC(=O)Nc1ccnn1Cc1cccnc1 +N#CCCN(Cc1cccnc1)c1c(N)cccc1Cl +CC(NC(=O)Nc1ccccn1)c1cccc(OC(F)F)c1 +c1cnc(OCC2CCC3C2OCCN3Cc2cccs2)nc1 +CCc1cccc(C)c1NC(=O)c1cc(OC)c(OC)cc1C +Cc1ccoc1C(=O)NCCCNC(=O)c1cn(C)nc1C(C)(C)C +O=C(c1ccc(S(=O)(=O)N2CCCC2)cc1)N1CCCCCC1 +COc1cc(OC)cc(C(=O)Nc2cnccc2C)c1 +Cn1cc(S(=O)(=O)N2CCCCC2)cc1C(=O)NCCCO +CNS(=O)(=O)c1ccc(C)c(C(=O)N(C)Cc2cc(C)on2)c1 +CC(=O)Nc1cc(C(F)(F)F)nn1-c1ccccc1Cl +O=C(NC1CCc2c(F)cccc21)c1n[nH]c2ccccc12 +CC(NC(=O)c1ccoc1)C(=O)Nc1cccc2cnccc12 +CC(O)CCN(C)C(=O)c1ccc(S(=O)(=O)NC2CC2)cc1 +Nc1ncccc1Cn1c(CCO)nc2cc(O)ccc21 +O=C(Nc1cc[nH]n1)c1ccc(CSc2ncn[nH]2)cc1 +Cc1ccccc1CNC(=O)c1[nH]c2c(c1C)C(=O)CCC2 +Cc1nc2ccc(NC(=O)c3cc4c(F)cccc4[nH]3)cc2o1 +CC(OC(=O)c1ccnnc1)c1ccccc1C(F)(F)F +CC(=O)Nc1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 +CCc1ccc(S(=O)(=O)N(CC(N)=O)C2CCCC2)s1 +CC1CCN(C(=O)c2cc(Cl)c[nH]2)c2ccccc21 +COc1ccc(C)cc1NC(=O)COc1cccc(N)c1 +Cc1noc(C)c1CNc1ccc(Cl)cc1NC(=O)c1ccco1 +OC(c1ccccc1)C1CCN(c2ncnc3[nH]ncc23)CC1 +O=C(c1ccncc1F)N1CCCSc2ccc(Cl)cc21 +COc1ccsc1C(=O)Nc1ccc(C(=O)N(C)C)c(C)c1 +CSc1ccccc1NC(=O)N1CCOCC1 +COc1ccccc1OCCN(C)C(=O)C1CCN(C(C)=O)CC1 +O=C(CCc1ccccn1)N1CCC(CN2CCc3ccccc32)CC1 +Cc1cc(C(F)F)nn1CC(=O)N1CC2CCC(C1)N(C)C2=O +O=C(CN1CCCCCC1=O)NCCc1ccccc1F +COc1ccc(CN(C)C(=O)CC(C)(C)C)cc1OC(F)F +CCc1ccc(CC)c(NC(=O)NCC2CC(=O)N(C3CC3)C2)c1 +CC(C)Cc1ncc2c(n1)CN(C(=O)CCNS(C)(=O)=O)C2 +CCOC(=O)CSc1nnc(-c2c[nH]c3ccccc23)n1C1CC1 +CCn1ccc(C(=O)Nc2cc(-c3ccccn3)no2)n1 +CC(=O)c1c[nH]c(C(=O)N2CCCC2C(=O)Nc2nccs2)c1 +O=S(=O)(CCN1CCN(c2cnccn2)CC1)c1ccccc1 +COCCCNC(=O)N(Cc1ccccn1)C(C)C +Cc1cccc(NC(=O)C2(C)Oc3ccc(Cl)cc3NC2=O)n1 +COc1ccc(NC(=O)c2ccc3c(=O)n4c(nc3c2)CCCC4)cc1 +O=C(Nc1ccc(S(=O)(=O)NCc2ccco2)cc1)c1ccoc1 +CC(O)CNC(=O)c1ccccc1Oc1ccccc1 +CCC(C)n1ncc(C(=O)NC2CCN(C(C)=O)C2)c1C1CC1 +Cc1nc(C)n(CCNc2nc(-c3cccnc3)nc3c2cnn3C)n1 +CC1CC1C(=O)Nc1ccccc1N1CCOCC1 +COc1ccc(C(C)=O)cc1CN1CC(C)CC1=O +COc1ccc(Cl)cc1CS(=O)(=O)c1nc(C)cs1 +Cc1ccc(C)c(NC(=O)CNS(=O)(=O)c2cnn(C)c2)c1 +O=C(Nc1ccc2sncc2c1)c1ccc(C(F)(F)F)nc1 +Cc1ccc(C(=O)CSc2nnc(-c3cccnc3)o2)cc1 +O=C(Nc1nc2ccc(F)cn2n1)c1cnc(C2CCCO2)s1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2cccc(N)c2)cc1 +CC(C)c1cnc(NC(=O)c2scnc2C2CC2)s1 +C#CCNC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1OC +COCC(=O)NC(C(=O)N(C)c1cccc(C)c1)C(C)C +CC1Oc2c(cc(Cl)cc2C(F)(F)F)NC1=O +CCOC(=O)Nc1ccc(S(=O)(=O)NCc2ccccc2)cc1 +CC(=O)c1c(C)nc(C)nc1SCc1csc(-c2ccco2)n1 +NC(=O)C1CCCN1C(=O)CSc1ccc(F)c(F)c1 +COc1ccc2nc3oc(C(=O)NCc4ccc(C)o4)cc3cc2c1 +CCc1c(C(=O)CN2CCOc3ccccc32)[nH]c(C)c1C(C)=O +Cc1ccc(-c2ncc(C(=O)N(C)CC3(CO)CC3)c(=O)[nH]2)cc1 +Cc1ccc(S(=O)(=O)NCC(O)c2ccccc2)cc1C +CCOc1cccc(OCC(=O)N2CCN(CCO)CC2)c1 +NC(=O)CCOc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1 +Nc1cc2c(nn1)CCN(C(=O)c1cccc3c1OCO3)C2 +Cn1cc(NC(=O)c2cc(NC(=O)Cc3ccccc3)n(C)n2)cn1 +Cc1ccccc1C1CC1C(=O)N1CCC(C(=O)NC(C)C)CC1 +CCc1cc(NC(=O)c2c[nH]nc2-c2ccccc2F)[nH]n1 +CC(NC(=O)c1ccoc1)C(=O)OC1CCCc2ccccc21 +COc1ccc(C(C)OC(=O)C(C)OC)cc1F +CCC(C)NS(=O)(=O)c1ccc(C(=O)N2CCC2)cc1 +O=C(OCc1ccc(F)cc1)C1CCCN1C(=O)c1cccs1 +O=c1ccc(-c2cccc3ccccc23)nn1Cc1ccccn1 +COc1cccc(C2CCCN2S(=O)(=O)N2CCCCCC2)c1 +CN(CC(=O)NC1CC1)C(=O)c1cc2c(ccc3ccccc32)[nH]1 +O=C(Nc1ccc(-c2nnc3n2CCCC3)cc1)c1ccncc1F +Cn1nc(C(=O)Nc2cccc(OCCCC#N)c2)ccc1=O +O=C(CCC(O)c1ccccc1)N1CCc2ccccc2C1 +CC(=O)Nc1ccc2c(c1)C(O)=Nc1cccnc1O2 +Cc1ccc(-c2nnn(-c3ccc(C)cc3)c2N)cc1 +COc1cccc(CCC(=O)NC(C)C)c1Cl +CC(OC(=O)CSc1ccncc1)c1cccnc1 +CCOC(=O)N1CCN(C(=O)c2cn(-c3cccc(F)c3)nn2)CC1 +COC(=O)c1cccc(NC(=O)Nc2c[nH]c(=O)[nH]c2=O)c1 +CC(Cc1ccc(O)cc1)N(C)C(=O)NCc1cn2ccsc2n1 +COc1cc2[nH]c(=O)c(C(C)=O)cc2c(OC)c1OC +CCOC(=O)c1cccc(NC(=O)c2ccc3c(c2)nnn3C)c1 +Cc1ccc(N2CCCC(Nc3ccc(C#N)cn3)C2)nn1 +CCCCN(CCO)C(=O)NCc1ccc(C#N)cc1 +CCS(=O)(=O)c1ccc(O)c(NC(=O)CCc2cnn(C)c2)c1 +COC(=O)c1sc(NC(=O)C(C)(C)C)c(C(N)=O)c1C +CNC(=O)C(CC(C)C)NC(=O)c1cc(Cl)c[nH]1 +CCN(CC)C(=O)c1cc(S(=O)(=O)NC)ccc1C +Cn1c(C(=O)NCc2cccnc2)cc2c1c1ccccc1n2C +O=c1c2c([nH]c3nc(-c4cccnc4)nn13)CCC2 +COc1cccc(Cn2c(C)c(C)c(S(C)(=O)=O)c2N)c1 +O=C(NCc1noc(CCc2ccccc2)n1)C1CCCCC1 +O=C(COc1ccccc1)N1CCC(c2cnccn2)CC1 +O=C(c1c(F)cccc1F)N1CCc2ccccc21 +CCc1cccc(C)c1NC(=O)c1ccc2ccccc2n1 +CC(C)(C)C(NC(=O)c1c(F)cc(Br)cc1F)C(N)=O +O=C(NCCCn1ccnc1)C1CCN(C(=O)c2cccs2)CC1 +Cc1nnc(NC(=O)CCc2ncc(-c3ccccc3F)o2)s1 +O=C(N=c1[nH]nc2n1CCCC2)C1(c2ccccc2)CC1 +COc1ccc(CCNC(=O)NCC#Cc2ccccc2OC)cc1 +Cn1nccc1CNC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +Cc1cc(Cl)cc(C)c1NC(=O)c1ccccc1 +CC(C)C(Nc1ncnc2cc(F)c(F)cc12)c1nc(C2CC2)no1 +CC(CNC(=O)NC1Cc2ccccc2C1)Cn1cccn1 +O=C(CCSc1ccccc1)NCc1ccncc1 +Cn1nc(C2CCN(C(=O)c3ccccn3)CC2)c2nccnc21 +CN(C)C(=O)c1cccnc1-c1cc(F)cc(Cl)c1 +Fc1cccc(N2CCCC2)c1CNc1cnn(CC(F)F)c1 +O=C(NCc1ccco1)Nc1ccc2c(c1)CCO2 +COc1cc2c(cc1F)CCNC2c1ccncc1 +CNS(=O)(=O)c1ccc(C)c(NCCC(C)(C)C)c1 +COc1ccc(COC2C(CO)OC3OC(C)(C)OC32)cc1 +COc1ccc(-c2noc(COc3ccccc3C(N)=O)n2)cc1 +COCC1CCCN(C(=O)NC(C)C(=O)N2CCCCC2C)C1 +CN(CC1CC1)C(=O)c1cccc(Oc2ccccc2)c1 +COc1cccc(CNC(=O)C2CN(S(C)(=O)=O)C2)c1 +Cc1ccc(Br)c(NCc2csnn2)c1 +Cc1ccc(C2(CNC(=O)c3ccccn3)CCOCC2)cc1 +CN(CC(=O)NC1CC1)C(=O)C(C)(C)Oc1ccc(F)cc1 +COCc1cc(NCC2CN3CCCC3CO2)nc(C(C)(C)C)n1 +Cc1cc(C)n2nc(CC(=O)NC3(C(N)=O)CCCCC3)nc2n1 +COc1ccc(NC(=O)CSc2ccc(F)cc2)cc1OC +COc1ccc(OCC(O)Cn2c(=O)cnc3ccccc32)cc1 +CC(=O)Nc1nc(C(=O)OCc2nc3ccccc3o2)cs1 +Cn1nccc1C(=O)N1CCCCC1c1nc(-c2ccncc2)no1 +COc1ccc(-c2nc3sc(C4CCCO4)nn3c2C#N)cc1 +N#Cc1nncn1Cc1nc(-c2cccc(C(F)(F)F)c2)no1 +Cc1cccc2sc(N3CCN(C(=O)C4CCC4)CC3)nc12 +Cc1cc2c(cc1C(=O)NCc1ccco1)OCCCO2 +CCn1nc(C(=O)Nc2nnc(-c3ccc(Cl)cc3)o2)cc1C +NC(=O)CN(Cc1ccccc1)C(=O)c1cc2ccccc2c(=O)[nH]1 +CCCCC1CCCC1NC(=O)c1csc(COC)n1 +Cc1nc(C)n(CC(=O)Nc2cccc(C(=O)N(C)C)c2)n1 +CCN(CC)C(=O)C(C)(C(F)(F)F)C(F)(F)F +Cc1cc(NC(=O)c2ccc(COc3ccccc3C#N)o2)no1 +CN(Cc1cn(-c2ccc(Cl)c(Cl)c2)nn1)S(C)(=O)=O +COc1ccc(-c2cc[nH]c(=O)c2C#N)c(OC)c1 +O=C1OCCC1Sc1ccc(S(=O)(=O)N2CCOCC2)cn1 +CC(=O)c1ccc(C)c(S(=O)(=O)NCC2CCCO2)c1 +CC(C(=O)N1CCOCC1)N1CCN(C(=O)Cc2ccc[nH]2)CC1 +COc1ccccc1C(O)c1cc2c(c(C)c1C)NC(=O)C2 +NC(=O)c1cccc(CNC(=O)Nc2ccn(Cc3ccccc3)n2)c1 +Cc1ccc(CNS(=O)(=O)c2ccc(N)cc2F)o1 +Cc1ccccc1-c1cc(NC(=O)Cn2ncn3nccc3c2=O)[nH]n1 +Cc1ncsc1CCOCCCn1ccc(N)n1 +CNS(=O)(=O)c1ccc(C(=O)N2CCCC2c2cnn(C)c2)o1 +C#CCCCOC(=O)c1ccc(-n2ccnn2)cc1 +Cc1cccc(CS(=O)(=O)NC2(C#N)CCN(C)CC2)c1 +Cc1cc(C)nc(CN(C)C(=O)c2cnc(C)c(C)c2)c1 +COc1ccc(N(C)S(=O)(=O)c2ccccc2)cc1OC +Cc1c(-c2nnc(C(=O)NCC3CCCO3)o2)oc2c(C)cccc12 +CCCCNc1nc(C2CCCCC2)nc(OC)c1N +Cc1cc(F)c2c(c1)CCCN2Cc1cc(=O)n2nc(C)sc2n1 +COC(=O)C1Cc2ccccc2CN1S(=O)(=O)c1ccc(F)cc1 +CC1(C)COC(c2ccccc2)CN1CCS(=O)c1ccccc1 +O=C(NCC1(c2ccc(F)cc2)CC1)C1CCCN(C(=O)C2CC2)C1 +Cc1ccc(C(=O)Nc2cccc(CN(C)Cc3cscn3)c2)o1 +Cc1cc(C(=O)NC(C)CCO)cc(C)c1OCc1cccnc1 +CC(Oc1ccccc1)C(=O)NCc1nnnn1-c1ccc(F)cc1 +Cc1noc(-c2ccccc2)c1NC(=O)c1cc[nH]n1 +CC(C)(C)NC(=O)CNC(=O)c1ccc2c(c1)OCO2 +CCn1nc(NC(=O)C(C)Cn2cccn2)cc1C +O=S(=O)(NCc1cc(Cl)c2c(c1)OCCO2)c1ccccc1 +CCc1noc(CC)c1CNC(=O)Nc1cc(C)cnc1OC +CC(C)(CNC(=O)CCc1nc(-c2ccco2)no1)c1ccncc1 +O=C(CSc1nnc(NC2CC2)s1)c1ccc(F)c(F)c1 +COc1ccc(-c2nc(CCNC(=O)C3CCCO3)co2)cc1 +COc1ccc(F)cc1S(=O)(=O)NCC(O)c1sccc1C +O=C(Nc1ccccc1OCC(F)(F)F)c1csnn1 +O=C(Nc1cccc(O)c1)c1cccc(OCc2cscn2)c1 +CN(Cc1ccc2c(c1)OCO2)C(=O)C1CC2CCC1O2 +CN(C)C(C(=O)N(C)C1CCCCC1)c1c(F)cccc1F +COC(=O)C(C)NC(=O)COc1cc(Cl)c(Cl)cc1Cl +CCN(CC)C(=O)CN1CCN(C(=O)NC(C)C(C)C)CC1 +CCCOc1cc(C)ccc1NC(=O)Cn1ccccc1=O +COc1ccc(CNC(=O)c2cccc(NC(C)=O)c2)cc1 +COCC(C)Nc1ncnc(Nc2nc3c(C)cccc3s2)c1N +NS(=O)(=O)c1cccc(CNC(=O)c2cc3ccccc3s2)c1 +O=C(Cn1cc(Br)ccc1=O)NC1CCCCC1 +Cc1nn2c(nnc3c(=O)n(CCO)cnc32)c1-c1ccccc1 +CC(=O)Nc1cccc(NC(=O)c2ccc(Cl)cc2O)c1 +Cc1nn(C)c(C)c1C(C)C(=O)NC1CCCCC1OCCC(C)C +CC(C(=O)NC1CCCC1)N1CCN(c2ccc(F)cc2)CC1 +Cc1cnc(C(=O)NC23CC4CC(CC(C4)C2)C3)cn1 +CCOC(=O)c1c(C)nsc1NC(=O)c1ccccc1Cl +CN(CC(=O)Nc1ccc(Br)cn1)Cc1cncs1 +COc1cc(OC2CCCN(C(=O)OC(C)(C)C)C2)ncn1 +O=C(Cc1cc(Cl)c2c(c1)OCCCO2)NCc1ccco1 +CC(C)(C)c1ccc(C(=O)Nc2ccc(CNC(N)=O)cc2)cc1 +Nc1cccnc1NCCCNC(=O)c1ccc(F)cc1 +COc1cccc(Cn2nccc2NC(=O)c2ccncc2)c1OC +CN(c1ccc(OCc2ccc(Cl)cn2)cc1)S(C)(=O)=O +Cn1c(=O)c2cc(NC(=O)c3cccc(C#N)c3)cnc2n(C)c1=O +CC(C)CCNC(=O)C1CCN(c2ccc(Cl)cc2)C1=O +CN(Cc1nc(-c2cc3ccccc3o2)no1)S(C)(=O)=O +CC(=O)NCC(=O)Nc1ccc(CCN2CCOCC2)cc1 +Cc1ccc(S(=O)(=O)NCc2sccc2C)cc1 +COc1ccc(OCc2nnc(C)n2C)cc1F +CN(C)C(=O)c1nnn(-c2ccccc2)c1C(F)(F)F +CC(C)C(C)NC(=O)c1cccc(-n2cc(Br)cn2)c1 +CC(Oc1cccc(C#N)c1)C(=O)N1CCCCCC1c1ccncc1 +CC(C)NS(=O)(=O)c1ccc(NCc2nncn2C)cc1 +Cc1nc(CN2CC3(CCN(C(=O)N(C)C)C3)CC2=O)cs1 +COCCCc1nc2scc(CC(C)C)c2c(=O)[nH]1 +Nc1cc(-c2ccccc2)cc2nc(C3CC3)oc12 +Cc1ncc(CNC(=O)Nc2cccc(Br)c2)s1 +CC(CNC(=O)CN(C)S(C)(=O)=O)CN1CCCC1=O +COc1ccc(C2c3c(oc4ccccc4c3=O)C(=O)N2C)cc1 +CCn1cnc(NC(=O)N(C)Cc2cccc(SC)c2)n1 +CNC(=O)Cc1nc2cc(-c3ccc(C)cc3)sc2c(=O)[nH]1 +O=c1[nH]nc(SCc2ccon2)n1C1CCCCC1 +COc1cc(N)ccc1NC(=O)c1ccc2c(c1)OCO2 +CCOc1ccc(C(=O)NCC(C)CC(C)O)cc1 +O=C(Nc1nccs1)c1ccc(COC2CCCCC2)o1 +CCCC(C)(NC(=O)Cc1c(C)noc1C)C(=O)OC +CC(Cc1ccccc1F)NC(=O)NCC(C)(C)NS(C)(=O)=O +CC(C)(CNC(=O)N1CCOC(C(N)=O)C1)c1ccc(Cl)cc1 +O=C(CNC(=O)NC1CC1)Nc1ccc(Cl)cc1 +COC(=O)CN1CCC(OCc2ccc(F)cc2)CC1 +COc1cccc(SC(C)C(=O)N2CCN(C(C)=O)CC2)c1 +CC(O)c1ccc(F)cc1OC1CCCCNC1=O +CCN(CCC#N)S(=O)(=O)c1c(C)c(C)cc(C)c1C +CC(C)c1cc(-c2nn3c(-c4ccccn4)nnc3s2)[nH]n1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)c1cc2ccccc2oc1=O +CC1CCCCN1C(=O)NCc1cc(F)ccc1F +COc1cccc(OC)c1COC(=O)C(C)c1c(C)noc1C +Cc1nonc1C(=O)Nc1ccc(-n2cccn2)cc1 +O=C(NCc1cccnc1)C(O)c1ccc2c(c1)CCCC2 +CC(=O)Nc1ccc(OCc2cccc(Cl)c2)cc1 +CC(C)Cc1nc(C(=O)Nc2cc(F)ccc2F)cs1 +CCC(C)OC(=O)C(C)n1c(C)ccc(C#N)c1=O +COc1ccccc1C(C)N1CCN(C(=O)Cc2cc(C)on2)CC1 +Cc1cc(C(=O)NCCS(=O)(=O)N2CCOCC2)ccc1F +Cc1ccn(CCn2ncc(N(C)Cc3ccccc3)cc2=O)n1 +CCCCNC(=O)NCC(=O)Nc1ccc(F)c(F)c1F +CCC(CNc1ncnc2c1cnn2CCO)c1ccccc1 +COc1ccc(OCCC(=O)Nc2ccc(N(C)C)nc2)cc1 +O=C(C1CC2C=CC1C2)N(Cc1ccccc1F)C1CC1 +Cn1c(=NC(=O)c2cnccn2)sc2cc3c(cc21)OCCO3 +CC(=O)N1CCc2cc(NC(=O)NCc3ccc4c(c3)CCC4)ccc21 +Cc1ccc(NC(=O)CCNC(=O)NCCc2ccccn2)nc1 +CC(C)Cn1cc(NC(=O)NC2(C)Cc3ccccc3C2)cn1 +Cc1cc(NC(=O)NC(CN2CCCC2=O)c2ccccc2)no1 +COCCN1CC2(CCN(C(=O)c3ccc(C)cc3)CC2)C1=O +CC1(C)CN(Cc2nc3sc4c(c3c(=O)[nH]2)CCC4)CCO1 +Cc1n[nH]cc1CN1CCN(C(C)C(=O)N2CCCCC2)CC1 +CCOCCCNC(=O)c1cc2ccc3ccc(C)nc3c2[nH]1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)c1ccncc1 +CCOC(=O)N1CCN(C(=O)Cc2ccccc2F)CC1 +Fc1ccc2c(c1)CCN(Cc1nc3ccc(F)cc3o1)C2 +CCC(C)NC(=O)C1CCC(c2ccccc2)N(C(=O)C2CC2)C1 +O=C1CCC(NC(=O)CCc2ccc(Cl)cc2Cl)CN1 +COc1cccc(CNc2nnc(-c3cccs3)o2)c1OC +CCc1ccc(CNC(=O)C2CC(=O)N(c3ccc(C)cc3)C2)cc1 +CCC(=O)Nc1ccc(OCC(F)(F)F)c(C#N)c1 +COC(=O)c1ccccc1SCC(=O)Nc1onc(C)c1C +N#Cc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1 +c1nc(N2CCC(c3n[nH]c(C4CC4)n3)CC2)c2nc[nH]c2n1 +CCN(CCNS(=O)(=O)CC)c1ccc2ccccc2c1 +O=C(NCCN1CCOCC1)c1nc(-c2c[nH]c3ccccc23)no1 +Cn1c(C2CC2)nc2c1CCN(CC(=O)NC(C1CC1)C1CC1)C2 +CCOC(=O)c1cn[nH]c1-c1ccc(OC)c(OC)c1 +CC(=O)c1ccc(NC(=O)NCCCn2cnc3ccccc32)cc1 +CCCC(=O)Nc1nn2c(C(C)C)nnc2s1 +COC(=O)C1CC2CCCCC2N1Cc1ccc(C(N)=O)cc1 +COCCOc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1 +CN(CC(=O)N1CCNCC1)C(=O)c1cccn1C1CC1 +C=CCn1c(C)nnc1SC(C)c1nc2ccccc2c(=O)[nH]1 +COC1CCN(C(=O)C(C)CS(=O)(=O)c2ccc(F)cc2)CC1 +CC(C)CCNC(=O)c1ccccc1S(C)(=O)=O +Cc1cccc(C)c1OCCOC(=O)Cn1ccc(=O)n(C)c1=O +O=C(Nc1cc[nH]n1)c1ccc(Br)c(F)c1 +O=C(Nc1cnn(-c2ncccn2)c1)N(Cc1ccccc1)C1CC1 +O=C(Nc1cccc2cnccc12)c1ccc[nH]c1=O +CCN(CC)C(=O)CCn1nc(C)c(C(C)=O)c1C +COC(=O)C1C(C)=NC2(O)c3ccccc3C(=O)C12O +NC(=O)Cc1nc(C2CCOC2)n(-c2ccccc2Cl)n1 +Cc1cccc(CNC(=O)Nc2cnccc2C)n1 +Cc1c[nH]nc1C1CCCN1C(=O)c1scnc1C +CCNC(=O)C(C)Sc1nc(C2CC2)nc2ccccc12 +O=C(c1cc2c(s1)CCCC2)N1CCOc2ccc(CO)cc2C1 +COc1ccc(CC(C#N)C(=O)N(C)c2ccccc2)cc1O +CCOC(=O)C(CC(N)=O)=C(NC)C(F)(F)F +Cc1nn(-c2ccccc2C(F)(F)F)c(=O)c2noc(C)c12 +CCNC(=O)C(C)NC(=O)Cc1cccc(F)c1 +CCOC(=O)c1cc(NC(=O)c2cc(C)c(F)cc2F)[nH]n1 +COc1cccc(C2CCCN2C(=O)c2ccnc(-n3ccnc3)c2)c1 +CN(C)C(=O)COC(=O)c1cccc(-n2ncc(C#N)c2N)c1 +CC(C)C1C(=O)NCCN1Cc1cnc(C(C)(C)C)s1 +CCn1c(N)nc2cc(C(=O)N(C)CCc3scnc3C)cnc21 +Cc1ccccc1C(=O)N1CCC(C(=O)Nc2ccccc2F)CC1 +O=C1CSc2ccc(C(=O)N3CCOc4ccccc43)cc2N1 +CC(NC(=O)NC1CC1C)c1ccc(NC(=O)c2ccncc2)cc1 +O=C(NCc1ccccc1N1CCOCC1)N1CCOCC1C1CC1 +CC(C)c1ncncc1C(=O)NCCNc1ncccc1C#N +Cc1n[nH]c(C)c1Cc1nncn1-c1cccc2ccccc12 +CCOC(=O)c1nnc(Cc2ccccc2F)o1 +O=C1Cc2ccccc2N1Cc1ccc(F)c(F)c1 +O=C(Nc1cccc(Br)c1)c1c[nH]ccc1=O +O=C(COc1cccc2cccnc12)N1CCc2ccccc21 +CC(C)C(=O)NCc1nnc(C(=O)Nc2ccccc2)s1 +COc1ccc(CN2CC(C(=O)NC(C)C3CCCO3)CC2=O)cc1 +CCCCN(C)C(=O)Cn1nnc(-c2ccc(C)cc2)n1 +CC(C)(C)c1ccccc1NC(=O)NCC(=O)NC1CC1 +C#CCN(C(=O)C1COc2ccc(F)cc2C1)c1nccs1 +Cc1n[nH]cc1CN1CCCC(c2nc3ccccc3n2C(C)C)C1 +Cc1ncsc1CCC(=O)NCc1noc(C2CCCC2)n1 +N#CCc1ccc(NC(=O)NCCc2ccc(-n3cccn3)cc2)cc1 +CC(=O)Nc1ccc(OS(=O)(=O)c2cccc(F)c2)cc1 +COc1ccc(CC(=O)Nc2cccc3nc(C)ccc23)cc1 +CCc1onc(C)c1NC(=O)c1cccc2[nH]ccc12 +O=S(=O)(CCn1nnc(-c2cccs2)n1)c1ccccc1 +CCCCNC(=O)C1CCCN(C(=O)Nc2ccncc2)C1 +CC1CCc2c(sc3ncnc(Sc4ncn[nH]4)c23)C1 +Cc1cc(C)c(NC(=O)COC(=O)c2n[nH]c3ccccc23)c(C)c1 +CCC(C(=O)N(C)CCN1CCCCC1=O)n1cccn1 +O=C1NCCN(C(=O)c2ccc3[nH]ccc3c2)C1c1ccccc1 +O=C(c1cccs1)N1CCC2(CC(=O)N(c3ccccn3)C2)C1 +Cc1cccc(C(=O)Nc2cccc(N3CCCS3(=O)=O)c2)c1O +CC1CCN(C(=O)c2ccc(-c3ccco3)o2)CC1 +COc1ccc(OC)c(C(C#N)NCc2ccco2)c1 +CCCOc1cc(Cl)c(C(N)=O)cc1OCCC +Cc1csc(C2CN(Cc3ncc(C(C)(C)C)o3)CCO2)n1 +Cc1cc(C(=O)CN(C)c2cnn(C)c2)c(C)n1C1CC1 +CC(C)c1ccc(NC(=O)CNS(=O)(=O)c2cnn(C)c2)cc1 +Cc1csc(CSc2nnc(-c3ccccc3C)n2C)n1 +N#Cc1ccc(NCCC(O)c2ccc(F)c(F)c2)cc1 +O=C(CN1CCN(C(=O)C2CCCC2)CC1)NCc1ccco1 +C=CCNC(=O)c1nn(-c2ccc(C)c(C)c2)nc1CO +O=C(Cc1cccc(F)c1F)N(C1CCCC1)C1CC1 +Cc1ncsc1C(=O)NCc1cccc(COC(C)C)c1 +CCN1CC(c2nc3ccccc3n2Cc2ccc(OC)cc2)CC1=O +N#Cc1cccnc1Oc1ccc(CN2CCOCC2)c2cccnc12 +Cc1ccc(NC(=O)CN2CCN(c3ncccn3)CC2)c(C)c1 +Cc1cccc2c1NC(c1cc(Cl)c3c(c1)OCCO3)NC2=O +COC(=O)C1(N(C)C(=O)CNC(=O)C(C)(C)C)CCCCC1 +Cc1cc(NC(=O)COc2ccccc2C(C)C)n(C)n1 +Cc1noc(CCC(=O)C(C#N)c2ccc(C(F)(F)F)cn2)n1 +CC(NC(=O)CCc1nc(C(C)(C)C)no1)c1cccnc1 +Cc1ccc(C(C)NC(=O)CCc2ccccc2O)o1 +NC(=O)c1cccc(NC(=O)CCC(=O)c2ccccc2)c1 +CC(NC(=O)NC1c2ccccc2CC1C)C(=O)N1CCCCC1 +CC(C)OC(=O)CNC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CN(CC1CCCC1O)C(=O)c1cn(C)nc1C(C)(C)C +COc1ccc(Cl)cc1C(=O)Nc1ccc(CNC(N)=O)cc1 +COc1cnc(C(=O)Nc2ccc3nc(CC(C)C)[nH]c3c2)cc1O +Cc1nn(C)c(C)c1NC(=O)CNC(=O)CC(C)(C)C +CC(=O)N1CCN(C(=O)Nc2ccc3c(c2)CCC3)CC1 +CSc1ccsc1C(=O)Nc1ccc(C(=O)NCC(N)=O)cc1 +CC(C)C(=O)NCCNC(=O)N1CCC(Oc2ccccc2)CC1 +Cc1cc(OCC(=O)OCC2CCC(=O)N2)ccc1Cl +Cc1nc(-c2ccsc2)sc1C(=O)N1CCC(CC(N)=O)CC1 +CCNc1ncc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)s1 +CCc1nnc(COc2ccc(Br)cc2C(C)=O)o1 +COc1ccccc1CCN(C)C(=O)c1c(C)c(C)nn(C)c1=O +COC(=O)NCC(=O)N1CCCC(C)c2ccccc21 +COc1ccccc1OC(C)CNC(=O)Cc1ccc(F)c(F)c1 +CN(C)C(=O)c1ccc(CNC(=O)Nc2ccc(F)c(Cl)c2)cc1 +CCN(CC(F)(F)F)C(=O)c1ccc(SC)cc1 +COCC(=O)Nc1ccc2c(c1)CN(C(=O)c1cccs1)CC2 +CCNC(=O)CNC(=O)c1cc2ccccc2nc1N1CCCC1 +O=C(CN1CCOCC1)Nc1ccc(C(=O)N2CCCC2)cc1 +C#CCOc1ccccc1CN(C)C(=O)NC(C)(C)C +C#CCN1CCN(C(=O)NCC2C3Cc4ccccc4C23)CC1 +Cc1ccc(C(=O)Nc2nc(CC(N)=O)cs2)c(C)n1 +Cc1ccc(Cl)cc1NC(=O)NCc1ncoc1C +CC(C)(CNC(=O)N1CCCC(CC(N)=O)C1)Cc1ccccc1 +Cn1c(C(=O)N2CCOC3CCCCC32)cc2ccccc21 +CN(CC(=O)N1CCC(CC(N)=O)CC1)S(C)(=O)=O +CC(COc1ccccc1C(F)(F)F)NC(=O)Cn1cnnn1 +CN(C)C(=O)c1ccc(Cl)c(NCc2nnc(C3CC3)o2)c1 +CCCNC(=O)Nc1cc(S(=O)(=O)N(CC)CC)cc(C)c1C +CC1CCCCC1CNC(=O)c1cc(N)cc(N)c1 +Nc1ccc(SCC(=O)N2CCCc3ccccc32)cn1 +Cc1c(C)c(C)c(S(=O)(=O)Nc2ccc(=O)n(C)c2)c(C)c1C +COc1ccc(-c2cc3nnc(C)nc3s2)cc1 +COc1ccc(-n2ncnc2CCC2CCCO2)cc1 +CCCN(C(=O)c1ccon1)C1Cc2ccccc2C1 +NC(=O)c1cnc(NC(=O)c2cccnc2OCC(F)(F)F)s1 +Fc1ccc2c(c1)CN(Cc1ccc(-n3cncn3)cc1)CC2 +O=C(Cc1ccc2c(c1)OCC2)NCCn1ccc2ccc(F)cc21 +COc1cc(CNc2cnn(-c3ncccn3)c2)ccc1SC +Cc1nc(SCC(=O)NC2(c3ccccc3)CCC2)oc1C +CCN(CC)S(=O)(=O)NCC1(c2ccc(F)cc2)CC1 +O=C(Nc1cccc(O)c1)c1ccc(C(=O)c2ccccc2)o1 +CCC(NC(=O)c1cc(C)nn1C)c1ccc(C(C)C)cc1 +CN(C)C(=O)c1cccc(OC(=O)C2CC3CCC2C3)c1 +N#Cc1ccc(OCc2ccc(C(N)=O)cc2)c(Cl)c1 +COc1cnc(NC(C)Cc2ccsc2)nc1-c1ccnn1C +COc1cccc(C(=O)NCCc2cn(C)c3ncccc23)c1 +CCOc1ccc(NC(=O)NC2CCCn3nc(CC)nc32)cc1F +N#Cc1ccc(CNC(CO)Cc2ccccc2)s1 +Cc1ccc2c(c1)N(Cc1ccc(C)c(N)c1)CCN2 +COc1cccc(Cc2nc3ccc(N)cn3c2CC#N)c1 +Cc1c(C(C)Nc2cn[nH]c(=O)c2Cl)oc2ccc(F)cc12 +COCC(=O)NCc1c(C)nn(Cc2ccccc2)c1C +CCOc1ccccc1CNC(=O)Nc1cccc(C(=O)OC)c1 +Cc1ccc(C(=O)N(C)C2Cc3ccccc3C2)o1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)Nc3ccc(C)c(C)c3)ccc21 +Cc1ccc(C(=O)N2CCN(c3ncccc3Cl)CC2)n1C +CCCNS(=O)(=O)CCNC(=O)c1ccc2c(c1)OCO2 +C=CCNC(=O)c1ccc(OCc2ccc(F)cc2)c(N)c1 +COc1ccc(C2NCCc3ccc(OC)c(OC)c32)cc1 +COCCN1CCN(Cc2cc(C#N)ccc2OC)CC1=O +CCOCC(=O)Oc1ccc(C(=O)c2ccccc2)cc1 +CNc1snc(C)c1C(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +O=C(CSc1ccc2ccccc2c1)Nc1cn[nH]c1 +Fc1cc2c(cc1F)C(c1cnn3ccccc13)NCC2 +CC1Cc2ccccc2N1C(=O)CSc1nc(N)cc(N)n1 +CN(C)c1cccc(-c2nnc(SCC(N)=O)n2C)c1 +Nc1nccnc1C(=O)NCCOc1ccc(Cl)cc1 +COC(=O)C1CCCC1NC(=O)Nc1ccc(F)c(C)c1 +CCC(C)NC(=O)N1CCC(C(=O)NCCCO)CC1 +O=C(Nc1cccc(Cl)c1)C1CCN(C(=O)NC2CC2)CC1 +COc1cc(-c2nc(C)c(C(C)=O)s2)cc(OC)c1OC +O=C(CCCc1nc(-c2cccnc2)no1)Nc1ccccc1 +Cc1cc(C(F)(F)F)n2nc(-c3nnc(-c4ccncc4)o3)cc2n1 +CNC(=O)NCC(=O)Nc1cc(F)cc(OC)c1 +O=C(CCn1cncn1)N1CCCC2(C=Cc3ccccc3O2)CC1 +CN(C)C(=O)N1CCC(C(=O)N2CCCC2(C)C)CC1 +CC(C)NC(=O)c1nnn(-c2ccc(F)cc2)c1C1CC1 +CCOc1cccc2c1OCC(=O)N(c1cc(OC)cc(OC)c1)C2 +Cc1c(C(=O)NCCc2cscn2)cnn1-c1ccccc1Cl +CC(C)(C)C(=O)COC(=O)C1CC(=O)N(c2ccccc2)C1 +O=C(Nc1ccc2c(c1)OCO2)C1=C2c3ccccc3C(=O)N2CC1 +CCCC(C)NC(=O)C(C)Sc1ccc(C)cn1 +COCC(O)CN(C)c1nccn(C(C)(C)C)c1=O +Cc1cc(NCc2cccc(C(N)=O)c2)ccc1C(=O)OC(C)(C)C +Cc1cccc(NC(=O)Cn2ccc3c(C)nn(C)c3c2=O)c1 +Cc1nc2c(Cl)cc(C(F)(F)F)cn2c1CC#N +CCN(CCO)C(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +CCC(C)NS(=O)(=O)c1ccc(C(=O)NCc2ccco2)cc1 +CC(CN1CCOCC1)OC(=O)c1ccccc1Cl +CCC1(CO)CCCN(C(=O)Cc2ccc(OC)cc2OC)C1 +Cc1ccccc1NC(=O)C1CN(C(=O)c2cnccn2)C1 +CCCn1cc(C(=O)N2CCN(CCc3ccccc3)CC2)c(C)n1 +Cc1cc(CNc2ccc(CC#N)cc2)c(C)s1 +CCOc1cccc(C(=O)N(CC)Cc2ccncc2)c1 +CCOC(=O)COC(=O)Cc1ccc(F)c(F)c1 +O=C(Nc1cccc(Cl)c1)c1c[nH]c2c(Cl)cccc2c1=O +O=c1c(=Cc2ccco2)sc2nc(C=Cc3cccs3)nn12 +CC1(C)CN(S(=O)(=O)c2ccccc2C#N)CCO1 +CCc1c(C)nc2nncn2c1NCc1ccc(F)cc1 +COc1ccccc1NC(=O)c1cc(C(C)C)nc2onc(C)c12 +O=c1[nH]c(N2CCCCC2)nc2nccc(C3CC3)c12 +COC(=O)c1ccc(COC(=O)C2COc3ccccc3O2)cc1 +Cc1cc(C#N)ccc1C(=O)NCC(C)(C)c1ccncc1 +CCN(CC(C)C#N)C(=O)c1cnc2sccn2c1=O +Cc1ccc(S(=O)(=O)NC(=O)c2cccc3cccnc23)cc1 +CC(O)c1cccc(OCc2ccc(C#N)cc2)c1 +Cc1nonc1C1CCCN1C(=O)c1cccc(C#CC(C)(C)O)c1 +Cc1occc(=O)c1OCc1ccc(C(C)(C)C)cc1 +Cn1cc(S(=O)(=O)NCCN2CCOCC2C2CC2)cn1 +COc1cc(C(=O)NCC(C)C)sc1S(N)(=O)=O +COc1cc(C(=O)NCCOc2ccc(Cl)cc2)on1 +COc1ccnc(NCCc2n[nH]c(-c3ccco3)n2)n1 +Cn1nnnc1SCCC(=O)N1CCc2ccccc21 +Cc1ccccc1-n1ncc(C(C)(C)O)c1C(F)(F)F +CCc1ccc(C(=O)C(C)Sc2ncnc3c2cnn3C)cc1 +CCN(CC)C(=O)N1CCC(C(=O)N2c3ccccc3CC2C)CC1 +CCc1ccc(N2CC(C(=O)N(CC)CCO)CC2=O)cc1 +COC(=O)c1ccccc1Cn1cnc2c(N3CCCC3)ncnc21 +Cn1cccc1CNC(=O)CC1NC(=O)c2ccccc2NC1=O +Cc1nc(C(=O)N(C)C(C)Cc2ccc(Cl)cc2)ccc1C#N +C=CCOc1c(CN2CCNC(=O)C2CC)c(C)nn1C +COC(=O)c1cc(C)nc(N2CC(C)OC(C)C2)n1 +CC(C)N(C)S(=O)(=O)NCCNC(=O)c1cccnc1 +O=C(Cn1cnc2sc3c(c2c1=O)CCC3)c1ccc(F)c(F)c1 +COc1cccc(C(=O)Nc2cc(C#N)ccc2Cl)c1F +CC(C)Oc1cccc(C(=O)N2CCOCC2C2CC2)n1 +COc1ccccc1OCC(=O)Nc1c(F)c(F)c(F)c(F)c1F +COc1ccc(Cl)cc1C(=O)OCCc1c(C)n[nH]c1C +O=c1c(Oc2ccc(Br)cc2)nccn1C1CC1 +CC(C)N(C(=O)COc1ncnc2ccccc12)c1ccccc1 +O=C(Nc1nc[nH]n1)c1cc2c(s1)-c1ccccc1CC2 +Cc1cccc(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)c1C#N +N#Cc1ncn(-c2ncc(C(F)(F)F)cc2Cl)n1 +COc1cccc(OCC(=O)Nc2ccccc2)c1 +COc1ccc(CN(C(=O)Cn2c(C)csc2=O)C2CC2)cc1 +Cc1cc(C)n(CCC(=O)N2CCCC(n3cncn3)C2)n1 +N#CC(COC(=O)c1scnc1C1CC1)Cc1ccccc1 +Cc1ccc(N2CCCCS2(=O)=O)c(Br)c1 +Cc1ccc(C(=O)OCC(=O)Nc2ccc3c(c2)OCO3)cc1F +Cc1nnc(Sc2ccc3nnnn3n2)n1-c1ccccc1 +O=C1CCCN1c1ccccc1NCc1ccc(F)c(F)c1 +COCC(C)NC(=O)Nc1ccccc1C(=O)N1CCCCC1 +Cn1nc(C(F)(F)F)c2cc(C(=O)Nc3ccccn3)sc21 +CC(=O)Nc1cccc(C(=O)OCC(=O)c2cccc(Cl)c2)c1 +COc1cccc(CNC(=O)N2CCOCC2C2CC2)n1 +CN(C)c1ccc(NC(=O)c2csc(Cc3ccccc3)n2)nc1 +CCCCOC(=O)C1CCN(C(=O)c2ccc(F)cc2F)CC1 +Cc1nc2c(ccc3nc(NC(=O)c4cccs4)sc32)s1 +O=C(c1ccnc(-n2cncn2)c1)N1CCN(Cc2ccccn2)CC1 +Cc1cccc2c(CC(=O)NC(C(N)=O)C(C)(C)C)c[nH]c12 +COc1ccc(CCCNC(=O)c2ccc(-c3cncnc3)nc2)cc1 +Cc1ccc(C(=O)NCCCOC(C)C)cc1-n1cccc1 +CSc1cccc(NC(=O)Oc2cccnc2)c1 +CC(NC(=O)C1CC(=O)N(C)C1)c1ccccc1Br +Fc1cccc(NCc2nnc3n2CCCCC3)c1 +Cc1nn(C)c(C)c1CNC(=O)Cn1ccc2c(Cl)cccc21 +O=C(Cc1c(F)cccc1F)Nc1ccccc1-n1cnnn1 +CCNc1ccc(C(=O)NCC(=O)NC(C)C)cn1 +Cn1c(-c2ccc(OCC(=O)N3CCCC3)cc2)nc2ccccc21 +Cc1ccc(NC(=O)Nc2nnc(Cc3ccccc3)o2)cc1 +Nc1c(OCC2CCCO2)ccc2scnc12 +Cc1ccc(N2CC(C(=O)Nc3c(C)nn(C)c3C)CC2=O)cc1 +COC(=O)CCc1csc(Cc2ccc(F)cc2)n1 +CC(C)(C)n1cc(C(=O)NCCOc2ccccc2)cn1 +N#CCCN(Cc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CCc1ccc(CCC(=O)N2CCN(CCn3cncn3)CC2)cc1 +COc1ccc(F)c(-c2nc(Cn3cnc(C)n3)c(C)o2)c1 +CC1(C)CN(S(=O)(=O)c2cc(F)cc(F)c2)CCO1 +COc1ccc(CCC(=O)NC(C)c2ccc3c(c2)OCCO3)cc1 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1ccc(OCC(F)F)nc1 +COc1ccc(C)cc1CC(=O)NCC1(C(N)=O)CCOCC1 +O=C(Cc1noc(-c2cccc3[nH]ccc23)n1)NCc1ccccc1 +CN(C)C(=O)CN(Cc1cc(F)cc(F)c1)CC(F)(F)F +CCOc1ccc2cc(S(=O)(=O)NCc3cccnc3)ccc2c1 +O=C(c1cncc(Br)c1)N1CCCC1c1ccncc1 +COCCn1cc(NC(=O)NCC2CCOC2)cn1 +O=C(NCc1ccccc1)N1CCSc2ccccc21 +Cc1cnc(C)c(N2CCCC(CO)(CC3CC3)C2)n1 +CC(C)C(=O)N1CCC(Nc2ncnc3cccc(F)c23)CC1 +CCOCC(=O)Nc1cccc(Oc2ccncc2)c1 +Nc1ccc2nc(CC(=O)Nc3ccccc3)ccc2c1 +CC(C)(C)OC(=O)N1CCCC(c2ccccc2O)C1 +CCNC(=O)c1cccc(NC(=O)c2ccc(F)c(F)c2)c1 +Cc1cc(NC(=O)CSc2ccccc2)sn1 +O=C(c1cccs1)N1CCN(CCNS(=O)(=O)C2CC2)CC1 +COc1cccc(-n2ccnc2SCC2CCOCO2)c1 +C#CCNC(=O)CCc1ccc(S(=O)(=O)N2CCCCCC2)cc1 +CCOc1cc2c(cc1OC)C(c1cncn1C)NCC2 +Cc1cccc(N(CCC#N)C(=O)COc2ccccn2)c1C +CC(CCCO)NC(=O)Nc1cccc2c1OCCO2 +O=C1NCCN(C(=O)Cc2cccs2)C1c1ccccc1Cl +CN(Cc1ccsc1)C(=O)COC(=O)c1ccc(O)cc1O +Cc1nnc(SC(C(=O)NC2CC2)c2ccccc2)n(N)c1=O +CCC(C)NC(=O)c1cccc(CNC(=O)Nc2cccc(F)c2)c1 +Cc1cc(=O)n(CC(=O)Nc2ccc3c(c2)OCO3)c(N)n1 +Cc1csc(C(C#N)C(=O)c2sc(C)nc2C)n1 +CC(C)(C)C(COc1ccccc1F)NC(=O)c1cc[nH]c(=O)c1 +COCCOc1ncccc1C(=O)NC1c2ccccc2CC1O +Cc1ccc(-c2cnnn2Cc2ccccc2C#N)cc1 +O=C(NCC1CCCO1)c1nnsc1-c1ccccc1 +CC(O)CN(C)C(=O)COc1ccc(F)cc1F +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1ccc(=O)[nH]c1 +COC(=O)N1CCC(NS(=O)(=O)c2ccc(C)c(Cl)c2)CC1 +O=C1CCN(C(=O)NCc2nccn2Cc2ccccc2)CCN1 +COc1ccc2c(ccn2CC(=O)NCCc2ccco2)c1 +C#Cc1cccc(NC(=O)N2CCN(C(=O)N(C)C)CC2)c1 +CN(CCCCNC(=O)Nc1ccc(C#N)cc1)c1ccccc1 +Cc1cnc(C(=O)Nc2nc3ccccc3nc2N2CCCC2)cn1 +Cc1ccc(N2CCNCC2=O)cc1Br +CC(C)(NC(=O)c1cccc(-n2cnnn2)c1)c1cccc(F)c1 +O=C(c1cnc2ccccc2n1)N1CCC(N2CCNC2=O)CC1 +O=C(Nc1ccc(Cl)cc1O)c1ccn2ccnc2c1 +O=C(OCc1cc(-c2ccccc2)on1)C1CCC1 +COC(=O)c1c(NC(=O)CCOc2ccccc2)c(C)nn1C +CN(C)S(=O)(=O)c1ccc(-c2c(C#N)nnn2C)cc1 +Cc1cc(C(=O)Nc2ccc(F)c(F)c2F)no1 +CS(=O)(=O)N1CCC(NC(=O)Nc2cccc3[nH]nnc23)CC1 +CCCn1nccc1C(=O)Nc1ccc2c(c1)C(C)(C)C(=O)N2C +Fc1cc(COc2ccccc2)c2ncccc2c1 +CCc1onc(C)c1NC(=O)Nc1cc(Cl)ccc1F +CCOC(=O)c1[nH]cnc1C(=O)Nc1ccccc1C +COCCOc1ccc(Cl)cc1C(=O)NCc1ncn(C)n1 +Cn1cnn(CCOc2ccccc2C(F)(F)F)c1=O +Cc1ccc(CCNC(=O)C2Cc3cc(F)ccc3O2)cn1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCCCCC2)cc1Cl +CC(=O)N1C2CC3CCC2(CS1(=O)=O)C3(C)C +OCc1nnn(-c2ccccc2F)c1C1CCCCC1 +N#Cc1ccccc1NC(=O)COc1cccc(F)c1 +Cc1nc(-c2cccc(-c3noc(C4CCC4)n3)c2)cs1 +CCCN(CC)C(=O)CCc1c[nH]c2ccccc12 +CCCCn1nnc(CO)c1C(Cl)(Cl)Cl +COc1ccc2[nH]cc(CC(=O)NCCCn3nc(C)cc3C)c2c1 +Cc1nc(CNC(=O)C(C)c2cccnc2)c(C)s1 +CC1CCC(C(N)=O)CN1C(=O)Cc1cccc(Br)c1 +Cc1cc(Br)ccc1S(=O)(=O)N1CCN(C)CC1 +CCC(CO)NC(=O)Nc1ccc(OC2CCCC2)cc1 +O=C(NCc1cccc(F)c1)c1cccc(OCC(F)F)n1 +CC(=O)NC(C(=O)Nc1ccc(N2CCOCC2)nc1)C(C)C +CC1CN(CC(=O)NCCc2c[nH]c3ccccc23)CCO1 +N#Cc1cccnc1NCCc1coc(-c2ccccc2)n1 +Cc1nc(-c2ccccn2)sc1C(=O)N1CCOCC1CC(C)C +CCc1ccc(CN(CCOC)C(=O)C2C=CC=N2)cc1 +CCCn1cc(NC(C)c2scnc2C)ccc1=O +O=C(CNC(Cn1cccn1)c1ccccc1)Nc1cnccn1 +Cc1nc(CNC(=O)c2oc3c(C)cccc3c2C)oc1C +CCNC(=O)c1cn(C2CCCCCC2)c2cccc(N)c2c1=O +COC(=O)N1CCC(CNC(=O)CC(C)(C)C)CC1 +Cc1ccccc1-n1cnnc1SCC(=O)N(C)c1ccccc1 +Cc1nc(CSc2nnc3ccccn23)cs1 +CC(C)C(C(=O)NCCN1CCOCC1)N1Cc2ccccc2C1=O +Cc1ccc(C)c(OCC(=O)Nc2ccccc2C#N)c1 +CCC1CN(S(C)(=O)=O)c2cc(C(=O)CN)ccc2O1 +COCCNc1ccc(CNC(=O)Nc2ccc(F)cc2)cc1 +Cc1noc(CCCNC(=O)C2CCN(C(=O)OC(C)(C)C)C2)n1 +CCN(CCC#N)C(=O)CNc1ccn(-c2ncccc2Cl)n1 +CC(=O)Nc1ccc(-n2ccnc2-c2nccn2C)cc1 +CCn1c(C(C)NC(=O)C(NC(C)=O)C(C)C)nc2ccccc21 +COCCCNC(=O)Nc1ccc(F)cc1Br +CC(C)OCCCNC(=O)C1(C)Cc2ccccc2C(=O)O1 +CCCC(=O)Nc1cc(C)c(NC(=O)CCC)cn1 +NC(=O)c1c(NC(=O)Nc2cccc(Cl)c2)sc2c1CCCC2 +O=S(=O)(Nc1ccc2[nH]ccc2c1)c1ccc2c(c1)COC2 +O=C(CNC(=O)c1cccc2cccnc12)Nc1ccc(F)c(F)c1 +CCNC(=O)c1ccc(C)c(NC2CCOCC2)c1 +c1ccc(-n2nnnc2CSc2cccs2)cc1 +Cc1ccc(Cl)cc1-n1nc(C)c(CO)c1C +Cc1c(C)n(-c2ccccc2Cl)c2ncnc(N)c12 +COc1cc2c(c(OC)c1OC)CCOCC2O +NC(=O)CCCNC(=O)c1ccc(C(N)=O)nc1 +Cc1cc(C)cc(C(=O)NCC(=O)Nc2ccc3nc(C)oc3c2)c1 +CCC(C)(C)NC(=O)C(Sc1n[nH]c(N)n1)C(C)C +CCCCNC(=O)C(C)n1nnc(-c2cccc(C(F)(F)F)c2)n1 +CC(CCc1ccccc1)NC(=O)c1cc(C(N)=O)cs1 +CNC(=O)c1cc(C)ccc1NC(=O)Cc1ccc(C)nc1 +O=C(NC1CCC2(CC1)OCCO2)c1cn(-c2ccc(F)cc2)nn1 +CCN(CC(C)C#N)C(=O)CNc1ccccc1SC +CC(=O)N1CCN(C(=O)CCC(=O)c2cccc(N)c2)CC1 +Nc1cc(Cl)c(F)c(S(=O)(=O)NCC2CCCO2)c1 +O=C(CC1CCCO1)OC(c1ccccc1)c1ccncc1 +Brc1cncc(-c2n[nH]c3c2CNCC3)c1 +COC1CCCC1OC(=O)c1ccccc1Cl +CCN(Cc1ccc(OC)c(OC)c1)C(=O)CN1CCOCC1 +CC(C)CCNS(=O)(=O)c1cc2c(cc1Cl)NC(=O)CO2 +COC(=O)C(C)(C)NC(=O)c1ccc(C(F)(F)F)nc1 +O=C(Nc1nnc(C2CCCCC2)s1)C1CC1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C(=O)N(C)C)cc2)c1C +Cc1oc(-c2ccco2)nc1CC(=O)NCC(C)(C)c1ccncc1 +Cc1cc(C)n(-c2nc3c(c(=O)[nH]c(=O)n3C)n2C)n1 +Cc1cnc(C)c(N2CCCC(c3cc(=O)[nH]c(C)n3)C2)n1 +CNC(=O)CN(C(=O)Cc1ccccc1OC)c1cccc(F)c1 +Cc1ccc(OCC(=O)N2CC3COCC3(c3nnc(C)o3)C2)cc1 +COCC1CCCN1C(=O)Nc1cc(-c2ncco2)ccc1C +COc1ccnc(NC(=O)c2cccc(NC(=O)C3CC3C)c2)c1 +CCCC(=O)N1CCC(OC(=O)c2csc(-c3ccoc3)n2)CC1 +O=C(c1ccc2c(c1)OCO2)N1CCN(CC(O)C2CC2)CC1 +CC(Oc1ccc(C#N)cc1)C(=O)N(CCO)Cc1ccccc1 +O=S(=O)(c1ccc(Cl)c(Cl)c1)N1CCCC(CO)C1 +COC(=O)CCNC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cc1nn(C)c(C)c1CCC(=O)NCc1ccccc1Cl +N#Cc1ccc(C(=O)NC(C#N)c2ccc(F)cc2F)nc1 +O=C(CCc1ccco1)NCc1ccc(Cl)cc1 +COC(=O)CN1CCc2cc3c(cc2C1)OCCCO3 +Cc1noc2ncc(C(=O)N3CCCN(c4cccnn4)CC3)cc12 +Cc1coc(-c2n[nH]c3cccc(Br)c23)n1 +CC(C)n1cnc2c(-c3ccccc3)c[nH]c2c1=O +CCn1c(=O)c(SCC(=O)NC2CCCCC2)nc2ccccc21 +O=C(NCc1cscn1)N1CCN(Cc2ccncc2)CC1 +C#CCNC(=O)c1ccccc1NC(=O)c1cccc(OC(F)F)c1 +CCOC(=O)C(C)OC(=O)Cc1c(F)cccc1F +Cc1ccsc1C(=O)Nc1c[nH]cc(Br)c1=O +CCc1nc(CN2CCN(C(=O)CNC(=O)NC)CC2)cs1 +Nc1c(-c2ccc(F)c(F)c2)nc2c(F)cccn12 +CCOC(=O)c1ccc(Nc2nc(C)nc3onc(C)c23)cc1 +CS(=O)(=O)c1cc(C(=O)N2CCN(CCO)CC2)ccc1Cl +CCN(CC(=O)Nc1ccc(CNC(N)=O)cc1)c1ccccc1 +CC1CN(Cc2nc3c(s2)CCC3)C(C)(C)CO1 +O=C(c1cc2ccccc2[nH]c1=O)N1CCCC1c1ccsc1 +Cc1ccc(CNC(=O)Cc2c(C)noc2C)cc1 +Cc1cc(CNc2cnn(CC3CCCO3)c2)c(C)o1 +Cc1nc(CN(C)CCOc2ccc(F)cc2)cs1 +CC1CN(CCC(O)c2cccc(N)c2)CC(C)O1 +COC(=O)CC1CCCCN1C(=O)c1cccc(C#N)c1 +Cc1c(CC(=O)N2CCOC3CCCC32)nnn1-c1ccccc1 +CC(c1cccs1)N(C)C(=O)c1cccc(-n2cnnn2)c1 +CC1CCN(c2ccc(=O)n(CC(=O)NCc3cccnc3)n2)CC1 +NS(=O)(=O)Cc1ccc(NC(=O)c2ccc(F)cc2F)cc1 +Cc1nc(CCN2CCCCCC2=O)n(-c2ccc(Cl)cc2)n1 +Cc1[nH]c2ccc(F)cc2c(=O)c1SC(F)(F)C(F)F +O=C(c1csc(COc2ccc(Cl)cc2)n1)N1CCOCC1 +O=C(Nc1cccc(C(=O)N2CCCC2)c1)c1ccncc1F +CCNc1ncnc(NCCCN2CCOCC2)c1N +COc1ccc(NC(=O)NCC(OC)c2ccsc2)cc1 +Cc1ccc(NC(=O)COc2ncnc3sc(C)c(C)c23)cc1 +Cc1cccc(CCC(=O)Nc2ccc(CNS(C)(=O)=O)cc2)c1 +Cc1ccc(C(=O)CCc2nc(-c3ccncc3)no2)cc1 +Cc1cccc2c(=O)n(CC(=O)OC(C)CC(C)C)cnc12 +CCn1cc(C(=O)Oc2c(Cl)cccc2Cl)cn1 +CCOC(=O)N1CCC(NC(=O)Cc2cccc(F)c2)CC1 +O=C(Nc1cc(-c2cccnc2)n[nH]1)c1ccnc(OC2CCC2)c1 +CCOC(=O)C(C)NCc1cccc2cnccc12 +O=C1COc2ccc(C(=O)c3cc4ccccc4o3)cc2N1 +Cc1ccc(C(=O)N2CCCCC2c2nc(-c3ccncc3)no2)cc1 +CCC1Nc2cc3c(cc2N(CCCC#N)C1=O)CCCC3 +O=C(CSc1ccc(F)cc1)NCC1(CO)CC1 +CC(C)C(C)NC(=O)NCC(=O)NCCc1ccccc1 +Cc1nccn1-c1cc(CNC(=O)C2CCC2)ccn1 +CCCCCNC(=O)c1ccc2c(c1)CCN2S(=O)(=O)CC +O=C(Cn1nnc2ccccc2c1=O)NCCCC1CCCCC1 +COc1ccc2cnn(CC(=O)Nc3nncs3)c(=O)c2c1OC +CCn1cc(CN(C)c2ncnc3c2NC(=O)CN3)cn1 +Brc1cccc(OCCSc2ncn[nH]2)c1 +N#CCCC(=O)NCCc1c(F)cccc1Cl +CCc1nn(Cc2occc2C(=O)OC)c(=O)c(C#N)c1CC +O=C(Nc1nnc(Cc2ccccc2)s1)c1ccccc1F +Nc1ccccc1C(=O)N1CCC(Cc2ccccc2)CC1 +O=C(c1cccnc1)N1CCCC2(CC(OCC3CC3)CO2)C1 +C#CCN(Cc1ccc(F)cc1)C(=O)c1ccc(-n2cnnn2)cc1 +COCCNS(=O)(=O)c1cc(Cl)ccc1Cl +Cc1cc(C)cc(C(=O)NCC(=O)Nc2ccc(-n3ccnn3)cc2)c1 +Cc1ccc(C(=O)N2CCN(CC(O)c3ccc(F)cc3)CC2)s1 +CCC(=O)Nc1cccc(C(=O)N2CCCCC2)c1 +COc1ccc(C(C)=O)cc1CC(=O)Nc1nnc(C2CC2)s1 +COc1ccc(CN2CCOCC23CCC3)cc1O +N#Cc1cccc(C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)c1 +CCCCS(=O)(=O)N1CCc2cc(F)ccc2C1 +COc1cc(OC)c(NC(=O)CC(C)c2c(C)n[nH]c2C)cc1F +N#Cc1ccc(OC(=O)C2CCN(c3cnccn3)CC2)c(Cl)c1 +Cc1cc2nc(CCO)n(CC(=O)N(C)c3ccccc3)c2cc1C +CC(C)S(=O)(=O)N1CCN(CCn2cccn2)CC1 +CCCCn1nc(C(=O)Nc2ccnn2C2CCCC2)ccc1=O +CCOC(=O)c1sc(-c2cccc(C(N)=O)c2)nc1C +Cc1ccc(C(C)NC(=O)Nc2ccc3c(c2)NC(=O)CS3)cc1 +O=C(NC1CC1)c1ccc(S(=O)(=O)N2CCCC(O)C2)cc1 +Cc1ccsc1C(=O)Nc1c(C)ccc(N)c1C +Cc1nc(-c2ccc(C(=O)Nc3cccc(F)c3)cc2)no1 +CCCC(=O)c1ccc(SCCN2CCOCC2)cc1 +COc1ccccc1C(=O)Nc1cc(-n2cnnn2)ccc1Cl +CS(=O)(=O)c1ccc(F)c(NCc2ccccc2OC(F)F)c1 +COc1ccccc1-c1ccnc2c1c(=O)n(C)c(=O)n2C +CCCCNC(=O)NCCCN1CC(C)OC(C)C1 +CCN(CCC#N)c1ccc(S(C)(=O)=O)cc1N +C#Cc1cccc(NC(=O)CCNC(=O)c2cccc(C)c2)c1 +O=C1CN(C(=O)C(Cc2ccccc2)n2cnnn2)CCN1 +CCOC(=O)C1=C(CN(C)C2CCCCCC2)NC(=O)NC1C +CC(=O)c1c[nH]c(C(=O)Nc2ccc(OCc3ccccc3)nc2)c1 +CC(NC(=O)C(Oc1ccccc1)c1ccccc1)c1ccncc1 +CC(C)n1nccc1NC(=O)c1ccccc1Br +Cc1c(C#N)c(N)n(-c2ccc(F)cc2Cl)c1C +Nc1ccc(Cl)cc1S(=O)(=O)NCC1CCCCO1 +Nc1cccc2c1CS(=O)(=O)N(C1CCCC1)C2 +O=C(Cn1ccccc1=O)N1CCCC1c1ccccc1 +CC(=O)N1CCCC1C1CCCN1c1nc2ccccc2o1 +Cc1ccc(C(=O)CCC(=O)N(Cc2cnn(C)c2)C(C)C)cc1 +COC(=O)Cn1nc2cc(C)nc(Nc3cccc(C)c3)n2c1=O +O=C(CCCc1ccccc1)NCC(O)c1ccc(Cl)cc1 +Cc1nn(C)c(C)c1CN(C(=O)Nc1ccc2nn[nH]c2c1)C1CC1 +CC(C)CCC(=O)N(C)CC(=O)Nc1ccc(Br)cn1 +NC(=O)C1CCCCC1NC(=O)c1ccc(-n2ccnn2)cc1 +Cc1ccnn1-c1ccc(C(=O)OCc2ccc(C#N)cc2)cc1 +O=C(c1ccccn1)N1CC(c2nc(-c3cccc(Cl)c3)no2)C1 +COCc1nc(CN2CCCC(c3nnc4ccccn34)C2)cs1 +CNC(=O)c1cccc(CCC(=O)N2CCOCC2C2CC2)c1 +Cc1nc(-c2ccc(NC(=O)c3ccc(C)s3)cc2)co1 +O=C(c1cccc(NCCOc2ccccc2F)c1)N1CCOCC1 +CNc1nc(=O)c2ccccc2n1Cc1ccc(F)cc1 +O=C(CCNC(=O)c1ccccc1)Nc1ccc(Cl)c(Cl)c1 +CC(=O)c1cccc(NC(=O)Nc2ccc(-n3ccc(C)n3)cc2)c1 +Cc1nn(C)c2[nH]c(=O)c(CCC(=O)NCC3CC=CCC3)c(C)c12 +O=C(Nc1cccc2[nH]cnc12)c1c[nH]nc1-c1ccccc1Cl +O=C(COc1ccc2ccccc2c1)NCCNC(=O)C1CC1 +COCc1cc(NC(=O)c2cn(C)nc2C(C)(C)C)ncn1 +CC(C)c1cc(C(=O)NCCN2CCNC2=O)on1 +CC(C)c1cc(C(N)=O)c(NC(=O)C2CCCO2)s1 +CCOc1cccc(OCCC(=O)N2CCC(O)CC2)c1 +O=C(Nc1nnc(C2CC2)s1)C1C2CC3CC(C2)CC1C3 +Cc1ccc(C(=O)N2CC(c3nc4ccccc4[nH]3)C2)cc1C +COc1ccccc1CCC(=O)N1CCN(CCO)CC1 +Cc1noc(C)c1CC(=O)Nc1ccc(-c2cn3ccccc3n2)cc1 +O=C(NC1CCCCC1O)C1(c2ccccc2)CC1 +CCN(CC)C(=O)N1CCC(C(=O)NC2CCCC(C)C2C)CC1 +COc1ccccc1CCNC(=O)c1ccnn1C +COC(=O)c1ccc(F)c(CNC(=O)c2ccsc2)c1 +CCc1ccccc1NC(=O)Cn1c(-c2cccs2)noc1=O +CC(C)n1nnc(-c2ccc(C(=O)NCCc3ccccn3)cc2)n1 +CNS(=O)(=O)c1ccc(C(=O)Nc2ccc(C)cc2O)cc1 +O=C(CCc1ccccc1)NCC1CN(Cc2ccccc2)CCO1 +CCn1cnnc1CCNC(=O)c1ccccc1NC(=O)C(C)(C)C +Cc1csc(NC(=O)CSc2nnc(-c3ccccc3)[nH]2)n1 +C#CCOc1ccc(C(=O)NCC(O)c2ccc(F)c(F)c2)cc1 +CC(NC(=O)c1ccoc1)C(=O)NC(C)c1nc(C(C)(C)C)cs1 +COc1ccc(F)c(NC(=O)COCc2ccccc2Cl)c1 +CCN(CC)C(=O)C1CCCN1C(=O)c1cccc(-n2cnnn2)c1 +Cc1ccc(S(=O)(=O)Nc2nc(C)c(C(=O)N(C)C)s2)cc1 +Cc1sc2ncn(C3CCc4ccccc4N=C3O)c(=O)c2c1C +CC(C)N1CCN(C(=O)CCNC(=O)c2cccc3ccnn23)CC1 +CC(=O)N(Cc1ccc(NCc2sccc2C)cc1)C(C)C +COCCS(=O)(=O)c1ccc(C(=O)Nc2cccc(C)n2)cc1 +CC1CCN(C(=O)CNC(=O)OC(C)(C)C)C2CCCCC12 +CSc1ccccc1C(=O)Nc1cccc(F)c1 +COC(=O)CCCc1csc(NC(=O)c2[nH]c(C)cc2C)n1 +Cc1nn(C)c2sc(C(=O)Nc3cccc(-n4cnnc4)c3)cc12 +O=C(c1cc(C2CC2)on1)N(Cc1ccoc1)Cc1cccs1 +O=S(=O)(NCc1ccccc1Cl)c1ccccc1 +C=CCN(Cc1ccccc1)C(=O)C1Cc2ccccc2C(=O)O1 +Cc1ccc(NS(=O)(=O)c2cccc(-c3noc(C)n3)c2)nc1 +O=C(Nn1cnnc1)c1cccc(Cl)c1Cl +CNC(=O)c1ccc(CNC(=O)C(C)c2ccsc2)cc1 +Cn1c(CSc2ccc(F)c(F)c2)cc(=O)n(C)c1=O +CC(=O)N1c2ccccc2CC1C(=O)Nc1cc(C)nn1C(C)(C)C +CCCNC(=O)CNC(=O)NCc1ccc(C)cc1N(C)C +CNS(=O)(=O)c1ccc(C(=O)NCC2CCCc3ccccc32)o1 +CC(=O)Nc1nc2cc(NC(=O)Nc3ccccc3C)ccc2s1 +Nc1cccc(NC(=O)CCCOC2CCCC2)c1 +COc1cccc(N2CCN(C(=O)c3c(Cl)cnn3C)CC2)c1 +Cc1ccc(C)c(CNc2ccc(C(N)=O)c(F)c2)c1 +CC(c1ccccc1Cl)N(C)C(=O)c1cccc(OCC(N)=O)c1 +CCOC(=O)CCCn1nnc(-c2ccccc2)n1 +COc1n[nH]c(-c2cccs2)c1Br +CN(CC(C)(C)C)C(=O)Cc1ccc(F)cc1F +Cc1ccc(OCC(=O)N(C)C(C#N)CC(C)C)cc1 +C=CCN1CCOCC2(C1)CN(Cc1cccs1)CCO2 +CCC(CO)N(Cc1cccs1)C(=O)Cc1ccc(O)cc1 +N#CCn1cnc2c(cnn2-c2ccccc2)c1=O +CCNC(=O)C(C)NC(=O)c1csc(-c2cccs2)n1 +COc1ccc(CNC(=O)CCc2cccc(N)c2)cc1OC +Cc1ccc(C)c(N2CCN(C(=O)Cn3cccn3)CC2)c1 +CN(C(=O)CSc1ncccn1)c1ccccc1 +COc1ccc(CN(C)c2ncnc3[nH]nc(SC)c23)cc1 +COC(C)(C(=O)N(C)c1ccc(Br)cn1)c1ccccc1 +O=C(NCCC1CCCCC1)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCOC(=O)c1nn(CC)c2c1CN(Cc1cccc(OC)c1)CC2 +O=c1[nH]c(CSc2nc3ncccn3n2)nc2ccsc12 +Cc1c(C(C)O)cc2c(c1C)OCCC2NC(=O)C1CC1 +COc1ccnc(NC(=O)c2cccc3[nH]ccc23)c1 +CNC(=O)CCCNC(=O)NCc1ccc2cc(OC)ccc2c1 +CC(OC1CCCC1)C(=O)Nc1cccc(C#N)c1 +CCN(C(=O)CSc1nnc(C(F)(F)F)n1N)c1ccccc1 +COCCNC(=O)c1cc2cc(Br)ccc2[nH]1 +COc1ccc(NC(=O)N(CCc2cccs2)C2CC2)cc1OC +O=S(=O)(c1cccc(C(F)(F)F)c1)c1cnns1 +CCOC(=O)c1cccc2nc(C(C)O)n(CCO)c12 +CCc1nc(CCNC(=O)c2ccccc2COC)sc1C +Cc1noc(CCC(=O)Nc2cccc3cn[nH]c23)n1 +COCC(=O)NCc1c(F)cccc1OC(F)F +COc1ccccc1C(O)CCNc1c(C)cccc1C(C)C +Cn1cc(C(=O)OCC(=O)Nc2c(F)cccc2F)c2ccccc21 +CC(=O)N1CCCN(S(=O)(=O)N2CCNCC2)CC1 +Cc1cccc(-c2n[nH]cc2-c2ccc3ncnn3c2)n1 +COc1c(C)cc(S(=O)(=O)NCc2ccco2)c(C)c1C +CC(NC(=O)Cc1c(F)cccc1F)c1ccc(-n2cccn2)cc1 +O=C(NCc1cccs1)Nc1ccc2c(c1)CCO2 +Cn1ncc(Cl)c1C(=O)Nc1ccccc1Br +Cc1ncsc1C(=O)Nc1nc(-c2cccn2C)cs1 +CC(C)NC(=O)CCS(=O)(=O)N1CCNCC1 +CC(=O)c1c[nH]c(C(=O)N(C)C2CCC(C)CC2)c1 +CC(=O)Nc1ccc(OC(F)(F)F)c(Br)c1 +CC(C)c1cc(C(=O)NCc2nc3c(s2)CCCC3)no1 +O=c1cc(Nc2ccc(Cl)c(Cl)c2)[nH]c(=O)[nH]1 +COc1ccc(C2=CCN(C(=O)c3c(C)noc3C(C)C)CC2)cc1 +CC1(C)C(NC(=O)NCCc2cccc(F)c2F)C2CCOC21 +Cc1noc(C)c1CN(C)C(=O)NC(C)c1nc(C2CCCC2)no1 +Cc1c(Cl)cccc1N(CC(=O)NC(C)C)S(C)(=O)=O +Cc1ccc(C(=O)NCc2cccc(CO)c2)s1 +COc1cc2c(cc1N)CN(C)S(=O)(=O)C21CCOCC1 +Cc1cc(C2CCCN(Cc3nc(C4CC4)no3)C2)n[nH]1 +Cc1csc(NC(=O)Cc2csc(-c3ccsc3)n2)n1 +N#Cc1cccc(NC(=O)CCc2cccs2)c1 +CNc1ccnc(C(=O)N(CC(F)(F)F)C2CC2)c1 +Cc1cccc(C)c1NC(=O)COC(=O)c1ccccc1N +O=C(NCCCN1CCOCC1)Nc1ccc(Cl)c(Cl)c1 +O=C(Cc1ccc(Cl)cc1)Nc1cc(-c2ccncc2)n[nH]1 +CC(C1CC1)n1ncc2[nH]c(-c3cnn(-c4ccc(F)cc4)c3)nc21 +CNC(=O)c1ccc(Sc2ncc(C(C)C)n2C2CC2)nn1 +CCNC(=O)CN(C)C(=O)c1ccc(Cl)cc1 +Nc1cc(-c2nc(-c3cnccn3)no2)ccc1Cl +CN1C(=O)CCOc2c1cc(Cl)cc2C(F)(F)F +COc1cccc(CN2CCN(Cc3cc(F)cc(F)c3)CC2=O)c1 +CC(C(N)=O)N1CCc2c(ccc(Cl)c2N)C1 +Cn1nnnc1SCC(=O)N1CCN(c2ccccc2F)CC1 +O=C(c1ccc(O)c(Cl)c1)N1CCCCC1CN1CCOCC1 +Cc1c(NC(=O)N2CCCC2)c(=O)n(-c2ccccc2)n1C +CCOc1ccc(F)c(C(=O)N2CCC3(CCCC3)C2)c1F +CC(Oc1ccc(C#N)cc1)C(=O)Nc1ccc(Br)cn1 +NC(=O)C1CCN(C(=O)c2cnn(-c3cccc(Cl)c3)c2)CC1 +Cc1cccc(-c2cncc(C(=O)N3CCCCC3)c2)c1 +Cc1noc(C)c1Cc1nnc2sc(-c3c(C)nn(C)c3C)nn12 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1nc2ccccc2[nH]1 +Cc1cccnc1NC(=O)c1noc2c1CCc1sccc1-2 +CCC1CN(CC(=O)OC)c2cc(N)ccc2O1 +COc1ncccc1CN1CC(NS(C)(=O)=O)C2OCCCC21 +Nc1c(-c2cccc(Cl)c2)noc1C(=O)N1CCCCC1 +Nc1cccc(C(=O)CCNc2cccc(F)c2)c1 +CN(CC1CCN(C(=O)OC(C)(C)C)C1)c1ncc(F)cn1 +O=S(=O)(c1ccccc1)N1CCOc2ccccc21 +O=C(c1ccccc1Cl)N1CCC(n2cccc2)CC1 +COc1ccc(OC)c(C(O)CNc2ncccc2C(F)(F)F)c1 +CCn1c(CCCNC(=O)c2ccccc2)nc2ccccc21 +Cn1cc(CCC(=O)N(Cc2ccsc2)c2ccccc2)cn1 +Cc1nn(CCN2CCOCC2)c(C(F)(F)F)c1C#N +CCNC(=O)c1ccc(NC(=O)c2scnc2C2CC2)cc1 +CC(O)CN1CCN(C(=O)c2cccc3c2OCCO3)CC1 +COc1ccccc1C(C)NC(=O)C1CCN(C(=O)C(C)(C)C)CC1 +CN(CCC#N)C(=O)CCCNC1=NS(=O)(=O)c2ccccc21 +CN(C(=O)c1cccc(-n2cccn2)n1)c1ncccc1C#N +O=C(NCCNC(=O)c1cccs1)c1cnc2snnc2c1 +NC(=O)C1CCCC1NC(=O)NC1CCc2cc(Cl)ccc21 +CCCNC(=O)NCCCn1nc2ccccn2c1=O +CC(C)c1cccc(OC2CC2)c1S(N)(=O)=O +CC1CCCN(C(=O)C2CCN(c3ccc(C#N)cn3)CC2)CC1 +CN(CCCc1cc(-c2ccc(F)cc2)n[nH]1)C(=O)C1CCOCC1 +Cc1ccc(C)c(-n2nnc(C#N)c2-c2cccnc2)c1 +NC(=O)CCCn1nc(CO)cc1-c1ccc(Cl)cc1 +COc1ccc(C(=O)CSc2ccccn2)cc1F +CCOC(=O)c1sc(NC(=O)c2ccccc2C)nc1C +COc1ccc(C2NCCc3c(N)cc(F)cc32)cc1F +CC(C)CC(C)NC(=O)c1cn(C)nc1C(C)(C)C +CCc1nnc(CSc2nnc(CC)n2N)o1 +COCCCNC(=O)C1CCN(c2ccc(C)c(C)c2)C1=O +Nc1ccc(S(=O)(=O)NCCCc2cc(F)cc(F)c2)cc1 +CN(C(=O)c1ccc(N)cc1)c1ccc2c(c1)OCCO2 +O=C(NCCN1CCOCC1)c1ccccc1Cc1ccccc1 +CCn1c(=O)[nH]c2cc(-c3nc(-c4ccncc4)no3)ccc2c1=O +CCN(CCO)C(=O)c1oc2ccc(Br)cc2c1C +COc1c(C)cnc(CNC(=O)c2ccc(N(C)C)nc2)c1C +CCC1CCC(NC(=O)c2ccc3c(c2)OCCO3)CC1 +CC(NC(=O)c1ccccc1)c1nnc2ccccn12 +O=C(CNC(=O)c1cc(F)cc(F)c1)NCc1ccc(F)cc1 +CCOC(=O)c1cn[nH]c1S(=O)(=O)Nc1c(C)cccc1C +Cc1csc(NC(=O)c2ccc(C#CCO)cc2)n1 +CCc1noc(C)c1-c1nn2c(C(C)C)nnc2s1 +O=C(Nc1ccc(F)cc1)N1CCn2cccc2C1c1cccnc1 +Cc1noc(C)c1CN1CCN(C(=O)COc2ccccc2)CC1 +CC(C)(C)OC(=O)NCC1CCCCN1C(=O)c1ccsc1 +Cc1noc(C2CCCN2Cc2cnc(-c3ccccc3C)s2)n1 +CC(C)NC(=O)C1CC2CN(S(=O)(=O)C3CC3)CC1O2 +Cc1nc(CC(=O)N2CCN(c3ccc(F)cc3)CC2)cs1 +CC(NC(=O)NCC1CN2CCCCC2CO1)c1cnn(C)c1 +Cn1c(C2CC2)nc2cc(NC(=O)Nc3ccncc3)ccc21 +CCC(=O)N1CCCC(C(=O)Nc2cccc(-c3ncco3)c2)C1 +CC(=O)c1c[nH]c(C(=O)Nc2ccc3c(c2)OC2(CCCC2)O3)c1 +CC(=O)NCCC1CCCN(c2cc(C)ncn2)C1 +CC(=O)c1cc(Br)cc2c1OC(C)CC(=O)N2C +COc1ccnc(NC(=O)c2cc(F)ccc2Br)c1 +CC(NC(N)=O)C(=O)NCCNC(=O)c1ccccc1 +O=C1COC2(CCN(C(=O)c3cccs3)CC2)CN1CC1CC1 +Cc1cccc(OCCN(C)c2ncnc3[nH]cnc23)c1 +CCOc1cc(C(=O)N2CCNC(=O)CC2)ccc1OC +CCn1ccnc1Sc1cc(C)nc(COC)n1 +CC(C)Oc1ccc(COc2ccc(N)cn2)cc1 +Cc1cnc(C(=O)N2CCC3(CC2)C(=O)Nc2ccccc23)cn1 +CC(NC(=O)Cn1cccc(C(F)(F)F)c1=O)c1ccc(F)cc1 +N#Cc1ccc(C(N)c2nnc(-c3c[nH]cn3)o2)cc1 +Nc1nc(C2CCCN2C(=O)CO)cc(C(F)(F)F)n1 +CCCCNC(=O)CCc1nc(N2CCOCC2)c2c(C)noc2n1 +O=S(=O)(N1CCCC1)N1CCN(Cc2ccccc2F)CC1 +CCC(C)NC(=O)Cn1nc(C)cc1-c1ccco1 +O=C(Nc1cc(-c2ccncc2)no1)c1ccco1 +COc1c(C)cnc(CSc2nnnn2CC2CCCO2)c1C +Cc1nc(C2CCCN(c3ncccc3C#N)C2)no1 +Cc1cc(C)n(CCC(=O)Nc2cccc(C(F)(F)F)n2)n1 +O=C(COc1cccc(F)c1)NCc1ccc(F)cc1 +COCCN1CC(C(=O)Nc2ccc(N3CCCC3)nc2)CC1=O +COCCN1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1=O +Nc1cccc(S(=O)(=O)NCc2ccccc2Cl)c1 +COc1ccc(CC(=O)N(C)C(C#N)c2ccco2)cc1OC +CCc1c(C(=O)NCCCC(N)=O)cnn1-c1ccccc1 +Cc1cc(C)n(CC(=O)NCc2ccccc2)c(=O)n1 +Cc1ccccc1CN1CCN(c2ncnc3ccccc23)CC1 +CC(C#N)CN(C)c1ccccc1Br +Cc1ccccc1CNC(=O)NC(Cc1ccccc1)C(=O)N(C)C +Cc1ccc(NC(=O)C2CCCN(C(=O)NC3CC3)C2)cc1 +COc1ccc(CCNC(=O)c2cc3ccc(OC)cc3[nH]2)c(O)c1 +Cc1ccc(CNC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +C=CCn1c(SCCOC)nnc1C(C)(C)C +COC(=O)C1=C(C(=O)NC2CCCCC2)CCC1 +COC(=O)C(C)Cc1ccc2cc3c(cc2n1)OCCO3 +COc1ccc(CNC(=O)Cc2n[nH]c(=O)c3ccccc23)cc1 +CCOC(=O)NCCC(=O)Nc1ccc(Cl)c(C(=O)N(C)C)c1 +CCCOC(=O)C1=C(C)NC(=O)NC1c1ccco1 +O=C(CS(=O)(=O)c1ccc(F)cc1)NCCCc1ccccc1 +Cc1c(C(=O)Nc2ccc(F)cc2)cn2nc[nH]c(=O)c12 +CN(Cc1ccc(F)cc1)C(=O)c1ccc2c(c1)OCO2 +NC(=O)C1CCCCN1C(=O)COC(=O)C1(c2ccccc2)CC1 +CNC(=O)NCC(=O)NC1CC1c1ccccc1Br +c1cc(Cn2cccn2)cc(NC2CCOCC2)c1 +COC(CNC(=O)c1ccccn1)c1ccsc1 +O=C(c1nnn(-c2cccc(F)c2)c1C(F)(F)F)N1CCCCC1 +O=S(=O)(Oc1ccccc1)c1ccc2c(c1)OCCCO2 +COCC(=O)N1CCCc2ccc(NC(=O)Cc3ccsc3)cc21 +CCc1noc(CC)c1CC(=O)NCc1ncc(C(C)(C)C)o1 +CCc1cc2c(=O)n(C(C)C(=O)OC)cnc2s1 +Cc1cc(C(=O)Nc2cccc(-c3nnnn3C)c2)[nH]n1 +CCN(Cc1nc(CC(C)C)no1)S(C)(=O)=O +O=C(NCc1ccc2c(c1)OCO2)Nc1cc(Cl)ccc1F +COCCNc1nc(-c2scnc2C)cs1 +Cc1cccc(Br)c1C(N)C(F)(F)F +N#CCCN1CC2(CCCCC2)Nc2ccccc21 +O=C(c1cc(-c2ccc(O)cc2)n[nH]1)N1CC=C(c2ccccc2)CC1 +O=C(NCc1cscn1)N1CCc2cc(F)ccc2C1 +CN(C)C(=O)C1CCCN1C(=O)c1cnn(-c2ccccc2)n1 +CCC(=O)N1CCc2cc(C(=O)N3CCC4(CC3)OCCO4)ccc21 +Cc1ccc(O)c(NC(=O)C(CC(C)C)N2CCCCC2=O)c1 +C#CCN(Cc1ccc(F)cc1)C(=O)CC1OC(=O)c2ccccc21 +CC(=O)c1ccc(C(=O)OCc2cc(C)nc(C)n2)cc1 +COCCNC(=O)Cc1cc(-c2ccc3c(c2)CC(C)O3)on1 +CC1CCCC(NC(=O)CNC(=O)c2cc(F)cc(F)c2)C1 +Cc1nc(C)c(CC(=O)Nc2nccs2)c(=O)[nH]1 +Nc1cc(N)cc(C(=O)NCCc2ccsc2)c1 +CCC(C)(C)NC(=O)Cn1cnc2cc(F)ccc2c1=O +COCc1nc2c(N)cccc2n1Cc1cccc(F)c1 +O=C(NCc1ccc(C(=O)N2CCCC2)cc1)Nc1ccccc1 +CC(C)C(=O)c1ccccc1NC(=O)c1nccnc1N +COc1cc(Cl)c(C)cc1NC(=O)Cn1cnnn1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)Nc1ccc2oc(=O)[nH]c2c1 +O=C(Nc1nnc(C2CCCCC2)s1)N(CCO)CCCO +CCOc1ccccc1C(=O)N1CCc2ccc(N)cc21 +COC(=O)C1CCCCCC1NC(=O)c1ccn(C)c(=O)c1 +Cc1noc(C)c1CCC(=O)N=c1sccn1C +C=CCOc1cccc(NC(=O)N2CC(C)OC(C)C2)c1 +c1ccc2c(c1)OCC(Cn1ccnc1-c1c[nH]cn1)O2 +CCNC(=O)C(C)Sc1ncnc2sc(C)c(C)c12 +CC(c1cccnc1)N1CCN(Cc2cnc3ncccn23)CC1 +CCOc1ccc(S(=O)(=O)N2CCCCC2C)cc1OCC +CCc1cccc(C)c1NC(=O)C1CC(=O)N(C2CCC(C)CC2)C1 +O=C(NCc1ccccc1F)c1nnc2ccccc2n1 +COCCN1CC(c2nc(-c3ccc(OC)nc3)no2)CC1=O +CCc1nnc(SCC(=O)Nc2ccccc2)n1-n1cccc1 +CCc1nc2n(n1)CCCC2NC(=O)NC1CCCC1 +COc1ccc(C(=O)N(C)Cc2ncc(C)c(OC)c2C)c(OC)c1 +N#CCC1(COC(=O)c2ccc(-c3cscn3)cc2)CC1 +NC(=O)c1ccc(C#CCNC(=O)c2ccc[nH]c2=O)cc1 +CC(O)(CNC(=O)Cc1ccc(Cl)cc1)c1cccs1 +COc1ccc2c(c1)CCC1C2=CCN2C(=O)CCC12 +CC1(c2ccco2)Nc2ccccc2C(=O)N1Cc1ccco1 +CCOc1ccc(C2OCCC(C)O2)cc1OC +CC(CO)C(C)NC(=O)NC1CCCN(Cc2ccccc2)C1=O +CCN(CC)C(=O)c1cccc(NS(=O)(=O)c2cccs2)c1 +CCCn1nccc1NC(=O)c1cccc(NC(=O)NC(C)C)c1 +O=C(c1ccccc1)N1CCC(Oc2cnccn2)CC1 +CC1CCCC(NC(=O)NCCc2ccccc2)C1 +CCN(Cc1noc(C2CCC2)n1)C(=O)c1ccccc1F +CC(CNC(=O)N1CCN(Cc2ccccc2)CC1)N1CCOCC1 +O=C1CCN(C(=O)CN2C(=O)COc3ccc(Cl)cc32)CCN1 +Cc1cc(C(C)C(=O)N2CCn3c(C)nnc3C2)c(C)o1 +CCN(CC)C(=O)c1cccc(Oc2cnccn2)c1 +O=C(c1ccco1)N1CCc2ncnc(-c3ccsc3)c2CC1 +CCC1CN(C(=O)Nc2ccn(-c3ncccc3Cl)n2)CC(C)O1 +Cc1ncsc1CNCc1cc(Br)cc2c1OCC2 +Cc1ccccc1-n1c(C)nc2ccc(O)cc2c1=O +CCC(=O)N1CCCCC1C(=O)Nc1cccc(-c2nnnn2C)c1 +Cc1ccccc1OCCOC(=O)c1ccc(-n2cncn2)nc1 +CN(Cc1ccccc1)C(=O)Nn1cnc2ccccc21 +CN(C)c1ccc(-c2noc(C(=O)NCCO)n2)cc1 +O=C(Cn1cnc2c(oc3ccccc32)c1=O)OCc1ccccc1 +CC1(C)Oc2cc(O)ccc2N(CC(N)=O)C1=O +Cc1cc(CN2CCN(C(=O)NC3CCCCCC3)CC2)no1 +O=C(Nc1ccnn1Cc1cccc2ccccc12)c1cc[nH]c(=O)c1 +CCC(C(=O)Nc1cnc(OC)nc1)c1ccccc1 +Cc1nn(CC2(O)CCCCC2)c(=O)c2ccccc12 +CCOCC1CCCN(C(=O)c2ccc(COC)cc2)C1 +CC(Cc1ccccc1F)C(=O)NC(C)C(=O)N1CCOCC1 +CN(CCc1ccncc1)C(=O)c1cn2cc(N)ccc2n1 +CC(=O)N1CCCc2cc(S(=O)(=O)N(C)c3ccccc3)ccc21 +CCNC(=O)CCOc1ccc(C#N)cc1Cl +CC(=O)Nc1cccc(NC(=O)c2cc3ccccc3c(=O)[nH]2)c1 +CCn1cc(C(=O)Nc2cc(OC)ccc2OC(C)C)cn1 +CC(NC(=O)Cc1csc(-c2ncccn2)n1)C1CC1 +C=CCNC(=O)c1ccc(-c2ccc(C)cc2C)nc1N +Cc1cc(C(=O)N(CCC#N)Cc2cccnc2)c2[nH]ncc2c1 +COCc1nc(C(=O)Oc2ccc(NC(=O)C3CC3)cc2)cs1 +COCCNC(=O)CSc1ccc(C(C)=O)cc1 +CCn1nccc1C(=O)N1CCC(Oc2ccccc2OC)CC1 +COc1c(Cl)cccc1NC(=O)Cn1ccc(=O)[nH]c1=O +NC(=O)COc1cccc(C(=O)Nc2ccc(CC(N)=O)cc2)c1 +CCNC(=O)CN(CC)C(=O)CNC(=O)c1ccc(F)cc1F +O=C(NC1CCCCC1)c1cc2cn(C3CC3)cc2s1 +Nc1cc(F)cc2c(CC(=O)Nc3ccccn3)noc12 +Cn1cc(NC(=O)C2CCN(C(=O)c3ccc(F)cc3F)CC2)cn1 +CCCOC(=O)c1cc(-c2ccc(SC)cc2)nn1C +CCCCCNC(=O)c1cc(NC(C)=O)ccc1O +N#CCc1cc(=O)c2cccc(Br)c2[nH]1 +O=C(Cn1c(=O)cnc2ccccc21)N1CCC2(CCO2)CC1 +CCOC(=O)N1CCC(NC(=O)Nc2cc(F)ccc2F)CC1 +CC(=O)Nc1ccc(NC2COc3cc(O)ccc32)cc1 +CCN(Cc1cccc(C)c1)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +COc1cccc(CNc2ccccc2SC(C)CC#N)c1 +CC(C)N(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1cscn1 +CCc1nc2c(N)cccc2n1CC(=O)Nc1ccc(C)cc1 +COc1ccccc1C(=O)Nc1ccc(OC)c(S(N)(=O)=O)c1 +C=CCOCC1CC2OCCN(c3ccccc3)C2C1 +C=CCNC(=O)c1cnc(Cc2ccccc2)s1 +Cc1nc(C(=O)N(C)Cc2cccc(OC(F)F)c2)c(=O)[nH]c1C +COc1ccccc1NC(=O)Cn1cnc2c(nnn2C)c1=O +CCCNC(=O)c1cccc(CNC(=O)N2CCOC(C)(C)C2)c1 +Cc1ccc(NC(=O)C(C)c2cccs2)c(OCC(=O)N(C)C)c1 +CCOC(=O)N1CCC(NC(=O)NCCCn2cccn2)CC1 +Cc1ccc(NC(=O)CS(=O)(=O)c2nccs2)cc1 +COc1cccc2c(SCC(=O)NC(C)C)nccc12 +Cc1ccc(NC(=O)c2cc(C)n3nccc3n2)c(C)c1 +O=C(COc1ccc2c(c1)OCO2)N1CCC2(CC1)NCCNC2=O +CCc1ccccc1OC(C)C(=O)NCc1ccccn1 +CNS(=O)(=O)c1ccc(CCC(=O)Nc2cc(C)on2)cc1 +COc1ccc2c(c1)CC(C(=O)NCc1ccc(C)cc1)CO2 +CNc1snc(C)c1C(=O)NCCCN1CC(C)OC(C)C1 +COc1ccc(Cl)cc1NC(=O)CN(C)C(=O)c1cc[nH]c1C +CCC(C)N(C)C(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +CCN(C(=O)NCc1cccnc1-n1cncn1)C1CCCCC1 +CCn1nc(C)cc1C(=O)NCC(=O)NC1CCCc2ccccc21 +COc1cc(CNS(=O)(=O)c2ccc(F)cc2)ccn1 +CCNC(=O)c1ccc(N)c(OCC(=O)NC(C)CC)c1 +C#Cc1cccc(N(C(=O)c2ccc(=O)n(C)n2)C(C)C)c1 +O=C(NCC1CC1)C1(NCC(F)(F)F)CCCC1 +OCCSc1nccn1Cc1ccccc1F +Nc1cccc(Br)c1CS(=O)(=O)c1ccccc1 +C=CCCCN(C)S(=O)(=O)c1ccc(CC)s1 +COc1ccc(OC)c(C(C)NC(=O)NCc2cc[nH]n2)c1 +Cc1nc2cc(C(=O)N(C(C)C)C(C)C)ccc2n1C +CCc1ccc(NC(=O)N2CCC3C2CC(=O)N3CCOC)cc1 +Cc1c(C(=O)N2CCN(C)CC2)c(C(F)(F)F)nn1C(C)C +COC(=O)C1CC(OC(=O)c2ccc(OC)cc2)CN1 +COC(=O)CN1CCCN(C(=O)c2c[nH]c3cccc(F)c23)CC1 +CN(CCOCC1CC1)S(=O)(=O)c1cc(F)cc(F)c1 +C#CCn1cc(CN(C)C(=O)Nc2cc(F)ccc2OC)cn1 +COC(=O)CCNC(=O)Cn1cnc2ccccc2c1=O +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1cnc2ccccc2n1 +Cc1cc(C)cc(Cn2c(N3CCCC3)cc(=O)n(C)c2=O)c1 +Cc1cc(NC(=O)CCc2ccco2)ccc1N1CCCC1=O +NC(=O)COc1ccccc1C(=O)NCc1nnc2n1CCCCC2 +Cc1cc(C(=O)N(C)c2ccc(Br)cc2F)n(C)n1 +Cn1cc(-c2nc(Cn3cc(Br)cn3)cs2)cn1 +COc1cc(OC)c(NC(=O)C2COc3ccccc3O2)cc1Cl +CC(C)(C)NC(=O)c1cc(NC(=O)C2CC2)n(-c2ccccc2)n1 +CC(OC1CCCCCC1)C(=O)NC(CO)C(C)C +c1cc2c(cc1OCCc1nc3c(s1)CCN3)CCC2 +O=C(Nc1ccc2nn[nH]c2c1)c1cnn(-c2ccc(Cl)cc2)c1 +Cc1cnc(NC(=O)CSc2ncc(C#N)c(N)n2)s1 +C#CCn1c(C2CC(=O)N(c3ccc(Cl)cc3)C2)nc2ccccc21 +CC(NC(=O)c1ccoc1)C(=O)N1CC=C(c2cccnc2)CC1 +O=C(Nc1ccccn1)C1CCCN(C(=O)c2n[nH]c3c2CCC3)C1 +CN(Cc1cccc(C#N)c1)C(=O)Nc1nnc(C(F)(F)F)s1 +COc1cc(C)sc1C(=O)Nc1cccc(C(=O)NC2CC2)c1 +Cc1ccc(NC(=O)C(C)N2CCOc3ccc(N)cc32)cc1 +CNC(=O)c1cccc(N(C)CC(=O)Nc2c(C)cc(C)cc2C)n1 +CC(=O)c1ccc(-c2cnn(C(C)C(N)=O)c2)cc1 +Cc1cc(C(=O)N2CCN(Cc3nc(CC(C)C)no3)CC2)on1 +O=C(Nc1nnc(C2CC2)s1)c1ccc2c(c1)OCO2 +Clc1cccc(Cl)c1CCNCc1ccccn1 +O=C(COc1ccc(-n2cnnn2)cc1)N1CCCC2CCCCC21 +CC(C)CC(=O)NCC1CCN(C(=O)c2cc3ccccc3o2)CC1 +Cc1ccc(C(CC(=O)OC(C)C)NC(=O)c2cccs2)cc1 +Cc1nc2ccccn2c1C(=O)N1CCC(Oc2cnccn2)CC1 +CC(C)(C)C(=O)NCCNC(=O)c1c[nH]c2cccc(F)c12 +CCn1c(C2CCCN2C(=O)c2cnc(C)cn2)nc2ccccc21 +Cc1cc(C(=O)Nc2cc(-c3ccc(OC(F)F)cc3)no2)on1 +O=c1cc[nH]c(C2NCCc3ccc4c(c32)OCO4)c1 +CCOC(=O)c1nn(Cc2ccc(OC)cc2)c2ncccc12 +CCOc1ccc(-c2cc(-c3ccco3)[nH]c(=O)c2C#N)cc1 +CC(C)NC(=O)C1CCN(C(=O)CCC2CCCCO2)CC1 +Cc1cccc(S(=O)(=O)N2CC3CNC(=O)C(C)C3C2)c1 +O=C(Nc1cccc(Cl)c1)NC1CCN(c2nccs2)CC1 +Cc1ccc(CNS(=O)(=O)N(C)C2CCCCC2)s1 +Cc1ccc(Nc2nnc(SCc3nnc(C)o3)s2)c(C)c1 +CC(C)NC(=O)c1cnc2c(ccn2C2CCCCC2)c1 +O=C(c1ccccc1O)N1CCN(Cc2ccccn2)CC1 +CC(=O)Nc1ccc(C(=O)NCCCn2cccc2)cc1 +Cc1ccc(C(=O)OCC(=O)Nc2cccc(C(C)C)c2)cn1 +O=C(c1cccnc1)N1CCCC(c2nccn2Cc2ccccc2)C1 +Cc1cccc(-c2cn[nH]c2C2CCN(C(=O)C3CCCO3)CC2)c1 +COC(=O)c1sc2cc(C(F)(F)F)cnc2c1Cn1cncn1 +COc1ccc(OCC2CCCN(C(=O)CN3CCCC3=O)C2)cc1 +COc1ccc(CNS(=O)(=O)Cc2cccc(C)c2)cc1 +Cc1ccc(OCC(=O)Nc2cccc(CCC(=O)N(C)C)c2)cc1 +OCc1nnn(-c2ccc(F)cc2)c1C1CCCCC1 +CCc1ccccc1C1CC(=O)NCc2nc(N(C)C)sc21 +CC(=O)Nc1cc(C(=O)Nc2cc(C)cc3cccnc23)ccc1C +Cn1cc(N)nc1Cc1cccc(Br)c1 +CC(C)(C)c1noc(CCCc2nc(-c3ccncc3)no2)n1 +CC(=O)c1cnc(NC(=O)Cc2nc(-c3cccs3)oc2C)s1 +Cc1ccc(N(C)C(=O)c2ccc(=O)n(C)n2)c(C)c1 +Cc1nc(C)c(C(=O)OCc2nc3ccccc3s2)s1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cnn(Cc2ccccc2)c1 +Cc1occc1CN(C)C(=O)NCCS(=O)(=O)c1ccccc1 +CCOc1ccc(-c2ccc(C#N)c(=O)n2C(C)C)cc1 +CC(=O)N1CCc2cc(-c3cn4cccc(N)c4n3)ccc21 +COCCCNC(=O)NC1CCc2c(O)cccc21 +CCCS(=O)(=O)c1cn2cccc(N)c2c1S(=O)(=O)CCC +O=C1C(=O)N(Cc2cccc(C(F)(F)F)c2)c2ccccc21 +CCCOc1nc2ccccc2nc1N1CCOCC1 +Cc1ccc(Cl)cc1CC1Oc2ccc(N)cc2NC1=O +CSc1nsc(NC(=O)c2cc(=O)c3ccc(C)c(C)c3o2)n1 +CN(CCc1ccncc1)Cc1cccc(OCC#N)c1 +CC(COc1cccc(F)c1)OC(=O)C1CC(=O)Nc2ccccc21 +CCn1cc(C(=O)N2CCN(Cc3ccc(C(C)C)cc3)CC2)cn1 +O=S(=O)(c1cccc(F)c1)N1CCC(Oc2ccccc2)CC1 +O=C1CN(c2ccc(S(=O)(=O)C(F)F)cc2)CCN1 +CCOc1ncccc1C(=O)Nc1ccc(CN2CCCC2=O)cc1 +C#CCNC(=O)CC1CCN(C(=O)c2ccno2)CC1CC +CCCNC(=O)CCc1nc(-c2ccc(C#N)cn2)no1 +c1ccc(C2(CNCc3ccncc3)CCCC2)cc1 +O=C(NCCCO)Nc1cccc(OC(F)(F)F)c1 +C=CCNC(=O)N1CCCC(Cc2noc(C)n2)C1 +CCc1cccc(OCCN2CC(C#N)CC2=O)c1 +CCCc1ccc(OC(C(=O)N2CCNCC2)C(C)C)cc1 +COc1ccc2c(c1)CN(S(=O)(=O)N1CC(C)OC(C)C1)CC2 +CCn1nc(C)c2ccn(CC(=O)NCc3ccccc3)c(=O)c21 +Cc1ccccc1-n1nc(C(=O)OCc2ccccn2)c2c1CCC2 +Cc1ccc(NC(=O)NCCC(=O)OC(C)C)cc1C +COCCCn1c(=O)c2ccccc2n(Cc2ccc(C)cc2)c1=O +CCCCN(C)S(=O)(=O)c1cccc(F)c1C#N +Cc1ccc(OCC(=O)NC2CCCNC2=O)cc1 +Cn1cccc(NC(=O)NC2CCCCCC2)c1=O +CCc1nnsc1C(=O)Nc1cc(C)nn1C +Cc1noc(C)c1Cn1cccc(S(=O)(=O)N2CCCC2)c1=O +NC(=O)COC(=O)c1ncoc1-c1ccccc1Cl +CC(=O)N1CCC(c2nc3cc(Cl)ccc3s2)CC1 +CN(C)C(=O)CCNC(=O)Nc1ccc(F)c(Cl)c1 +CCOC(=O)c1cc(C)nc(N2CCOCC2)n1 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+Cc1nc(-c2cccnc2)sc1C(=O)Nc1ccccc1F +Cc1ccc2c(CC(=O)N3CCOC(c4cnn(C)c4)C3)coc2c1 +CCNC(=O)CNc1ccc(S(N)(=O)=O)cc1 +CC(C)CCNC(=O)c1ccc(N2C(=O)CCS2(=O)=O)cc1 +Cn1cc(CCNC(=O)Nc2nc3ccccc3s2)cn1 +Cc1ccc(Cc2nc(C(=O)NCCn3cnnc3C)cs2)cc1 +COCCOCCNC(=O)N(C)C1CCCCC1 +O=C(Nc1ccnc(Sc2ccccn2)c1)c1cc(C2CC2)on1 +O=C(C1CC2C=CC1C2)N1CCN(c2ccccc2)CC1 +Cc1cccc(NC(=O)CCn2c(=O)oc3ccccc32)c1C +Cc1ccc(CNS(=O)(=O)c2cc(-c3ccno3)sc2C)cc1 +COCCCNC(=O)CC(C#N)c1ccccc1Cl +CC(=O)NC(C(=O)NC(C)c1ccc(C(C)(C)C)cc1)C(C)C +CC(C)(C)OC(=O)NCc1cnc(C(F)(F)F)nc1 +CCC(CC)NC(=O)N1CCN(Cc2nc3ccccc3[nH]2)CC1 +COCCCNC(=O)Cn1cc(Br)cn1 +CC(C)(NCC(N)=O)c1cccc(C(F)(F)F)c1 +CNC(=O)c1ccc(S(=O)(=O)N(C)CCO)cc1 +COc1ccc(CNC(=O)c2cccc(-n3cnnc3)c2)c(F)c1F +CCCCS(=O)(=O)NCC(=O)Nc1ccc(Cl)cc1C +COC(C)(CNC(=O)c1cc(C)oc1C)c1cccc(Cl)c1 +Cc1ccc(CN2CCN(S(=O)(=O)Cc3ccccc3)CC2)o1 +CC(C(=O)N1CCC2(CC1)OCCO2)n1cnc2ccccc21 +CCC(NC(=O)Cn1c(=O)oc2cccnc21)c1ccc(Cl)cc1 +CCOc1ccc(NC(=O)C(C)Sc2nc3ncccc3o2)cc1 +O=C(Cn1ccnc1)NCc1ccccc1CN1CCOCC1 +N#Cc1ccnc(N2CCC3(CCC(=O)N(C4CCCC4)C3)CC2)c1 +Cc1ccncc1NC(=O)NCCOc1ccc(F)cc1F +C=C(C)CN(CC)C(=O)CN1c2cccc3cccc(c23)S1(=O)=O +Fc1ccc(-n2cc(-c3noc(-c4cccnc4)n3)nn2)cc1 +COc1cc(Nc2ccc(NC(=O)CC(C)C)cc2)nc(C)n1 +CCc1nc(C)c(C(=O)NCC2(c3cccc(F)c3)CCOCC2)o1 +Cc1cccc(NC(=O)C2CC=CCC2C(=O)N2CCCC2)c1 +COCCNS(=O)(=O)c1cccc(C(=O)N2CC(C)CC2C)c1 +O=c1ccc(S(=O)(=O)NCCC2CCCO2)c[nH]1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)oc(=O)n3C)nc1 +CC(=O)N1CCCC1C(=O)N1CCC(c2c[nH]c3ncccc23)CC1 +Cc1cc(C)n(-c2cccc(NC(=O)N(C)Cc3ccoc3C)c2)n1 +CC(C)NC(=O)Nc1cccc(C(=O)N(CC(F)F)C2CC2)c1 +Cc1cc2nc3c(cn2n1)C(=O)CC(c1ccc(F)cc1)C3 +CN(Cc1ccc2c(c1)OCO2)C(=O)Nc1ccccc1 +CCn1c(C)cc(C(=O)CSc2nc(-c3cccnc3)n[nH]2)c1C +Cc1ccc(N2CCC(C(=O)N3CC(C)CC(C)C3)C2=O)cc1 +Cc1ccc(NC(=O)C2CCN(C(=O)C3CC3)CC2)c(Cl)c1 +Cc1cccc(NC(=O)C(O)c2ccc(C)cc2C)c1 +Cc1ccccc1SCC(=O)NC1CCC(O)CC1 +CC(=O)Nc1cccc(CNc2cccc(F)n2)c1 +NC(=O)C1CCN(C(=O)NCc2ccccc2Cn2ccnc2)CC1 +Cc1cc(C)n2nc(SCc3cc(F)cc4c3OCOC4)nc2n1 +CCCCNC(=O)C1CN(c2nc3ccc(OC)cc3s2)C1 +CCN1CCC2(CN(c3ncccn3)CC2c2ccccc2)C1=O +CCCCC(=O)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1F +Cc1nn(CC(=O)NCC2CCCO2)c2ccccc12 +Cc1cc(=O)n2c(n1)SCC2(O)c1ccc(F)cc1 +CN(C)C(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1ccnc(NC(=O)NCCC(=O)Nc2ccccc2)c1 +CCN1CC(C(=O)Nc2nc(-c3ccc(OC)cc3)ns2)CC1=O +Cc1cc(C)c(NC(=O)COC(=O)c2ccco2)c(C)c1 +CC(C)(C)C(=O)NCC(=O)NCc1ccc(Cn2cncn2)cc1 +CC(Nc1cnn(CC(F)F)c1)C(=O)NC(C)(C)C +O=C(CN1CCOCC1)N1CCN(Cc2n[nH]c(=O)[nH]2)CC1 +CCC(NC(=O)C(C)NC(N)=O)c1ccccc1OC(F)F +Cc1nc(CN(C)C2CCN(C3CCOC3=O)C2)no1 +CC(=O)Nc1ccc(CC(=O)N2CCCC2c2ccc(F)cc2)cc1 +CC(C)N(C(=O)c1cccc(OCC(=O)N(C)C)c1)C1CCC1 +CCn1c(=O)n(Cc2nnnn2C2CC2)c2ccccc21 +Cc1cc2nc(C3CCCCN3C(=O)C3CCCO3)[nH]c2cc1C +CCc1nnc(SCC(=O)Nc2nnc(C(F)(F)F)s2)o1 +COc1ccc(C(=O)NC2CCOCC2)cc1Br +CC(C)(C)OC(=O)N1CCNCC1Cc1ccc(Cl)cc1 +COC(=O)Cn1nc2c(Oc3ccc(Cl)cc3)nccn2c1=O +CN(CC(=O)c1c[nH]c2ccccc12)CC1OCCO1 +O=C(c1ccoc1)N1CCN(c2nc3ccccc3o2)CC1 +O=C1CC2C(CC(O)C2C=CC(O)COc2cccc(Cl)c2)O1 +CCCc1nc(C(=O)NCc2ccc(N3CCCC3=O)cc2)cs1 +CCOC(=O)Nc1cncc(NC(=O)OCC)c1 +O=C(Cc1ccc(Cl)cc1)NC1CCN(c2ccc(F)cc2)C1=O +O=C(NCC1CC1)c1cc(F)ccc1C#CCCO +C=CCCC(O)CN1CCc2ccc(Cl)cc2C1 +CCc1ncc(C(=O)NCc2noc(C(N)=O)n2)cn1 +CCCCNC(=O)CCC(=O)N1CCOc2ccccc21 +O=C(Nc1cccc(C#Cc2ccccc2)c1)N(CCCCO)C1CC1 +COc1cccc(C(C)CC(=O)Nc2ccc3oc(=O)n(C)c3c2)c1 +Cc1noc(COC(=O)c2cnn(-c3ccc(F)cc3F)c2)n1 +CC(NC(=O)NCCc1cccc(Cl)c1)c1ccccn1 +COC(=O)c1cc(=O)n2c(n1)sc1cc(C)c(C)cc12 +Cc1noc(C)c1NC(=O)C1CC1c1cccc(C(F)(F)F)c1 +CNC(=O)c1cccc(NC(C)C2CCOCC2)c1C +O=C(Nc1nccs1)c1cccc(OCC(F)F)n1 +CC(C)(C)NC(=O)Nc1cccc(Cn2cccnc2=O)c1 +CC(NC(=O)N1CCOC(C(N)=O)C1)c1cc2ccccc2o1 +Cc1cc(C)cc(CNc2ccc(C#N)c(C#N)c2)c1 +COC(=O)c1cnn2c1NC(c1cccs1)CC2C(F)(F)F +COCCN1CCN(C(=O)CCC2CC2)CC1=O +CC(C)Sc1ccc(N2CCC(C(=O)N(C)C(C)C)CC2)nn1 +CC(=O)Nc1ccc(F)c(NCC2CCOCC2)c1 +O=C(Nc1ccccc1F)c1ccc(-n2cccn2)nn1 +COCC(=O)N1CCOC2C(OCc3ccncc3)CCC21 +Cc1cnn(CC(=O)N2CCCN(c3ccc(C)nn3)CC2)c1 +O=C1NCCCc2[nH]c(-c3cc(-c4ccccc4)[nH]n3)nc21 +Cc1oc(C)c(S(N)(=O)=O)c1C(=O)N1CC(C)OC(C)C1 +O=C(NC1CCCOc2ccccc21)c1cccnc1OCC(F)F 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+CNC(=O)CCc1ccc(NC(=O)c2ccc(OC)cc2OC)cc1 +NS(=O)(=O)c1ccc(NC(=O)Cc2ccc(F)cc2F)c(F)c1 +N#Cc1ccsc1C(=O)N1CCCC1CC(=O)c1ccccc1 +COc1ccccc1-c1cnn2c(=O)c(CC(F)(F)F)c(C)[nH]c12 +Cc1cc(NC(=O)c2nccc3c(N)ccc(C)c23)no1 +COCC(=O)Cc1nc(N)nc(Nc2ccccc2)n1 +Cc1sc(NC(=O)c2ccncc2)nc1-c1ccc(F)cc1 +COc1cccc(C(N)=O)c1OCC(=O)NCc1ccc(Cl)cc1 +CCN(Cc1cnc2ccccn12)C(=O)Cc1ccccc1Cl +Cc1ccc(CNC(=O)Cn2nc3c(cc2=O)CCC3)cc1 +Fc1ccc(-c2oncc2-c2nnnn2-c2ccccc2)cc1F +Cn1cnc(CNC(=O)Nc2cccc(-c3nccs3)c2)n1 +O=C(c1cnn(-c2ccccc2)c1C(F)(F)F)N1CCOCC1 +CCCC(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +O=C(c1cc(F)cc(C(F)(F)F)c1)N1CC2CC=CCC2C1 +COC(=O)c1ccc(NC(=O)N2CC(C)CCC2C)cc1C +C#CCN1CCC(C(=O)NC(C#N)c2ccccc2F)CC1 +C=CCNC(=O)c1nn(-c2ccc(F)cc2)c(OCC)cc1=O +CNc1snnc1CSc1nnc2n1CCCCC2 +CC(C(=O)Nc1cc(F)ccc1F)N1CCc2cc(F)ccc2C1 +Cn1c(=O)c2c(C(F)(F)F)cc(-c3cccs3)nc2n(C)c1=O +NS(=O)(=O)c1nc(-c2ccccc2)oc1-c1ccccc1 +COCc1cccc(C(=O)NC(C)c2cccs2)c1 +CN1CC2(CCCN(C(=O)c3ccc4ncsc4c3)CC2)OC1=O +COCCC(=O)Nc1n[nH]c(Cc2cccc(F)c2)n1 +NC(=O)CNC(=O)c1ccc(Oc2ccc(C(F)(F)F)cn2)cc1 +CC(NCC(=O)N(C)CC1CCCCC1)c1ccncc1 +O=C(NCCC1=CCCCC1)C1CCN(c2cnccn2)CC1 +CN1CCC(C(=O)N2CCCCC2Cn2cccn2)CC1=O +Cc1ccc(NC(=O)CSc2nnc(N)n2C)c(C)c1 +Cc1ccnc2nc(C(=O)Nc3ccccc3SCCC#N)nn12 +CC(NC(=O)C(C)n1cccn1)c1ccc2c(c1)CC(=O)N2 +CCN1CC(C(=O)Nc2ccccc2-n2cnnn2)CC1=O +O=C(NC1CC2C(=O)N3CCCC3C(=O)N2C1)c1cc(F)ccc1F +CCCCn1nc(C(=O)NCCc2ccccn2)ccc1=O +Cn1cc(NC(=O)c2cccc(N3CCOC3=O)c2)cn1 +CCOCc1ncn2c1CN(C(=O)c1cc[nH]n1)CCC2 +CN1C(=O)CC2C1CCN2C(=O)c1ccncc1F +NC(=O)c1csc(C(=O)Nc2cc(F)cc(F)c2)c1 +O=C(Nc1ccncc1)c1cncn1-c1ccccc1 +CN1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +CCN(CC)C(=O)c1ccc(NC(=O)CNC(=O)NC)cc1Cl +COc1ccccc1OCCC(=O)Nc1cccc2cn[nH]c12 +Cc1c(Br)cccc1COC(=O)c1ccccn1 +COc1ccc(C2Nc3ccccc3C(=O)N2C)cc1 +Cn1ccc(NC(=O)c2cc3sccc3n2Cc2ccccc2)n1 +Cc1cc2occ(CC(=O)OCC(=O)NC3CC3)c2cc1C +O=c1[nH]nc(CN2CCN(c3cc(N4CCOCC4)ncn3)CC2)[nH]1 +CCCNC(=O)CNc1cc(C)nc2nc(-c3cccnc3)nn12 +O=C(NCCNC(=O)C1CC1)NCC1(c2ccccc2)CCOCC1 +CCc1nnc(SCC(=O)c2ccc(OC)cc2)n1N +C=CCNC(=O)C(C)Nc1ccc2nc(C)sc2c1 +CCCOC(=O)C1=C(C)Nc2nnnn2C1c1cccc(OCC)c1 +CC1CCC(N(C)C(=O)CN(CCCO)c2ccccc2)CC1 +CC(=O)Nc1cccc(NC(=O)c2cc(C)ccc2-n2ccnc2)c1C +Nc1cc(Cl)ccc1C(=O)NCC1CCCCO1 +CN1CCOC(C(=O)N2CCOCC2c2cccn2C)C1 +CCNC(=O)CN(CC)C(=O)C(C)Oc1cccc(Cl)c1 +CCn1cc(C(=O)NC2(c3ccc4c(c3)OCCO4)CCCC2)cn1 +COc1ccc(-n2cc(CNC(=O)c3ccc(C)nc3)nn2)cc1 +COc1cc(C(C)C)ccc1C(=O)c1nccn1C +COC(=O)c1sccc1S(=O)(=O)Nc1cccc(Cl)c1 +Cc1nc(CNC(=O)c2cccc(Cl)c2N)sc1C +Cc1nnc2n1CC(NC(=O)Cc1noc3ccccc13)CC2 +O=C(NCC(F)(F)F)c1cc(-c2cccc(Cl)c2)on1 +CC(C)c1nc(CNC(=O)NCCc2cccs2)cs1 +NC(=O)C(Cc1ccccc1)Nc1cc(N2CCOCC2)nc(N)n1 +COC(=O)C(C)CN(C)C(=O)c1ccc(C)c(N)c1 +CNC(=O)C1CCCN(C(=O)CCCc2c[nH]c3ccccc23)C1 +O=C(c1n[nH]c2c1CCCC2)N1CCn2cnnc2C1 +NS(=O)(=O)c1ccc(NC(=O)c2ccc(F)c(F)c2)c(F)c1 +CCOC1CCN(C(=O)Cn2c(=O)[nH]c(=O)c3ccccc32)CC1 +CC1(NS(=O)(=O)CCC2CCCO2)CCCc2ccccc21 +Cc1cc(C(=O)Nc2ccc(Cl)c(N)c2)c(C)o1 +CNC(=O)c1ccc(C(=O)N2CCC(Nc3cccnn3)CC2)cn1 +Cc1ccc2cccc(OCC(=O)Nc3ccccc3Cl)c2n1 +Cc1cn(C)nc1C(=O)Nc1nc(-c2cccnc2)cs1 +CCC(C)NC(=O)Nc1ccc(S(=O)(=O)C2CCCC2)cc1 +Cn1c(NCCC2=CCCCC2)nc2c1c(=O)[nH]c(=O)n2C +N#Cc1ccccc1NS(=O)(=O)Cc1ccccc1 +Cc1ccccc1-c1nnc(SCCCCC(=O)N(C)C)n1C +CSc1ccc(CNc2ncnc3ccsc23)cc1 +CCN(c1ccccc1C)S(=O)(=O)c1c(C)noc1C +Cc1ccc(OC(C)C(=O)Nc2nc(C)cs2)cc1 +Cc1oc(C)c(C(=O)NCc2ccc(N3CCCC3=O)cc2)c1C +COc1cccc(C2NCCc3ccc(C)cc32)n1 +CC1=C(C(=O)NCc2snnc2C(C)C)C(C)NC(=O)N1 +CN(C)S(=O)(=O)c1cccc(NC(=O)NC(C)(C)C)c1 +O=C(CNC(=O)c1ccc2c(c1)OCO2)OCc1ccno1 +O=C(Nc1cccc(F)c1)c1ccnc2ncccc12 +CCCc1nc(CNc2cccc(NC(=O)OC)c2)cs1 +CCCCOC(=O)c1ccc(NC(=O)c2cnc(C)cn2)cc1 +O=C(COc1ccc2nc3n(c(=O)c2c1)CCC3)Nc1ccncc1 +CCOC(=O)N1CCCN(S(=O)(=O)c2ccc(OC)cc2)CC1 +COc1ccc(CNC(=O)Nc2ccccn2)c(OC)c1 +O=C(Cc1ccc(Oc2nccc(C(F)(F)F)n2)cc1)NCCO +Cn1ncnc1CNC(=O)c1cc(C2CC2)nc2ccc(Cl)cc12 +CC(C)(CNC(=O)c1cccc(N2CCCC2=O)c1)c1ccncc1 +CCc1ncc(C(=O)N2CCCCC2CC)c(N)n1 +CC(NC(=O)COc1cccc(C#N)c1)c1ccc2c(c1)CC(=O)N2 +CN(C(=O)c1ccc2[nH]cnc2c1)C1CCCCC1 +CCS(=O)(=O)NCc1ccccc1S(=O)(=O)N1CCOCC1 +Cc1ccc(N2CCC(C(=O)Nc3nnc(C(C)C)s3)C2=O)cc1 +CC(C)(C)OC(=O)N1CCCCC1CNc1cnccn1 +NC(=O)C1(NCc2ccc3c(c2)OCCO3)CCCCC1 +CN(C(=O)CNC(=O)c1ccccc1)C1CCCCC1 +COCCCC(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +Cn1c(=O)n(CC2(O)CCCCC2)c2ccccc21 +C#CCCCCNC(=O)NCC1(c2ccc(F)cc2F)CC1 +O=C(CCCNc1ncccn1)Nc1ccc(Cl)cc1 +COC(=O)CCCCNC(=O)c1cc(Cl)ccc1O +COCC(Nc1cc(C)nc(-c2ccccc2)n1)c1ccccn1 +CCNC(=O)CCc1nc(-c2cc3cc(C)ccc3[nH]c2=O)no1 +O=C(NCc1ccc(Br)cc1)N(CCCCO)C1CC1 +O=C(Nc1ccc2c(c1)COC2)C1CCCN1C(=O)C1CCCC1 +CCOc1ccc(CNC(=O)Nc2cccc(C(=O)NC)c2)cc1F +Cc1ccccc1OCCCC(=O)N1CCCC1C(N)=O +CC(C)COCCCNC(=O)c1ccc(Cl)cc1N +CCN1CCOCC12CCN(C(=O)Cc1ccccc1)CC2 +CCN(c1ccccc1)c1ccc(S(=O)(=O)N(CC)CC)cn1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1c(Cl)cccc1Cl +COc1ccc(CNc2nc(C)c(C)c(=O)[nH]2)cc1 +CCCn1c(C)nnc1SC(C)C(=O)c1ccc(F)cc1 +Nc1cc(C(=O)N2CCCCC2)ccc1N1CCCC1 +CCc1nc(NCCCN2CCOCC2)c2cc(C)sc2n1 +CN(Cc1cn(-c2ccccc2)nn1)Cc1nnc(-c2ccccc2)o1 +Cc1ccc(C(=O)N2CCC(Oc3nncc4ccccc34)CC2)cc1 +NC(=O)CCCNC(=O)c1ccc(OC2CCCC2)cc1 +C#CCN1CCN(C(=O)NCc2ccc(S(N)(=O)=O)cc2)CC1 +COC(=O)c1nn(C)c(C)c1NC(=O)Cn1ccc(C)n1 +O=C(Nc1nnc(-c2ccc(F)cc2)o1)C1COc2ccccc2O1 +O=C(Nc1nnc(-c2ccccn2)s1)C1CCOc2ccccc21 +Cc1cc(C)nc(NC(=O)COc2cccc3ccccc23)n1 +CCn1cc(CNS(=O)(=O)c2cnn(CC)c2C)cn1 +COC(=O)c1ccc(NC(=O)NCc2cnn(C)c2C)cc1Cl +CCNC(=O)c1ccc(NC(=O)c2cccc(N(C)C)c2)c(C)c1 +CC(C)N(C)C(=O)CSc1nnc(-c2cccs2)n1C +COCc1nnc(SCC(=O)Nc2cccc(OC)c2)n1N +O=C(CCCc1ccccc1)Nc1nnc(-c2cccnc2)s1 +CCN(CC)C(=O)c1nc(CNC(=O)c2ccc(C)c(F)c2)oc1C +Cc1ncc(-c2ccc(S(=O)(=O)NC3CC3)cc2)o1 +Cc1ccc(NC(=O)c2cc3c(cn2)[nH]c2ncccc23)cc1 +COc1cccc(COC(C)C(=O)OC(C)C)c1 +COc1ncc(C2CC(=O)NCc3nc4ccccn4c32)cn1 +Cc1ccc(SCC(=O)Oc2cccc(C(=O)N(C)C)c2)cc1 +Cc1nnc(COC(=O)c2cccc(NC(C)C(C)C)c2C)o1 +CN(C(=O)c1cnc(-c2ccco2)nc1N)c1ccccc1 +Nc1c(C(=O)Nc2ccc(F)c(F)c2)nnn1Cc1ccc(F)cc1 +CCc1cccc(C)c1NC(=O)c1ncn(-c2ccc(Cl)cc2)n1 +CC(=O)Nc1cccc(OCCNC(=O)Nc2cnccc2C)c1 +NC(=O)c1ccc(CNC(=O)C2C3CC4CC(C3)CC2C4)cc1 +CC(=O)Nc1ccccc1OCC(=O)NCCc1ccccc1 +COC(=O)CNC(=O)N1CCCC1c1nc2ccccc2s1 +Cc1cc(NC(=O)C2CC(=O)N(c3cccc(C)c3C)C2)n(C)n1 +COC(=O)c1cccc(CCNC(=O)C2CCCN2C(C)=O)c1 +CCOc1cccc(C(=O)Nc2ccccc2F)c1 +O=C(COCc1nc2ccccc2[nH]1)N1CCC(c2ccccc2)C1 +O=C(Cc1n[nH]c(=O)c2ccccc12)NCCc1cccnc1 +O=C(COc1ccc(-n2cnnn2)cc1)NCc1ccccc1Cl +Cc1ccc(NC(=O)NCCC(=O)N2CCCCC2)nc1 +NC(=O)C1CCCN1C(=O)Cc1csc2ccc(Cl)cc12 +N#CC(Cc1ccc2c(c1)OCO2)c1ccc2c(c1)OCCO2 +c1cnc(N2CCCC(NCc3nc4c(s3)CCCC4)C2)nc1 +O=C(c1cccc(-n2cccn2)c1)N1CCC(n2cnnc2)CC1 +Cc1cccnc1C(NC(=O)c1cccc(S(C)(=O)=O)c1)C(C)C +COCc1cccc(C(=O)OCc2ccc(-n3cccn3)cc2)c1 +CNS(=O)(=O)c1cccc(CNS(=O)(=O)c2cccs2)c1 +COc1ccc(N(Cc2ccccc2)C(=O)Cn2ccccc2=O)cc1 +COc1cccc(SCC(=O)NCC(C)C)c1 +CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(F)c(F)c2)CC1 +c1cnn(CCCCCN2CCOCC2C2CC2)c1 +CC(CC(=O)c1cccs1)NC(=O)c1cccc2c1oc(=O)n2C +CC(=O)Nc1ccc(O)c(C(=O)NCCc2ccc(C)cc2C)c1 +Cn1cc(C(=O)N2CCN(CCNC(=O)c3cccs3)CC2)nn1 +N#Cc1ccc(Cn2c(C3CC3)nc3cc(N)ccc32)cc1 +CCCc1nc(CN2CCN(C(=O)c3ccc(C)cc3)CC2)no1 +CCc1nc2n(n1)C(CC(=O)Nc1ccc(NC(C)=O)cc1)C(=O)N2 +CC(=O)c1c(C)[nH]c(C(=O)NC(C)c2nc3ccccc3[nH]2)c1C +COc1ccc(Cl)cc1N1CC(C(=O)NC2CC2)CC1=O +CC(C)c1ccc(N2CCN(CC(=O)NC(C)(CO)CO)C2=O)cc1 +CC(C)c1cccc(C(C)C)c1NC(=O)CSc1nncn1N +O=C(NCc1ccc(S(=O)(=O)N2CCOCC2)cc1)C1CCC1 +CCn1c(=O)[nH]c2cc(-c3noc(C4CCC4)n3)ccc21 +CCn1cc(Cn2cc(CC(C)c3ccc(C)o3)nn2)c(C)n1 +Cc1ccc(-c2cc(C3CCN(C(=O)c4cnn(C)c4)C3)[nH]n2)cc1 +O=C(c1cccnc1)N(CC(F)(F)F)C1CCOCC1 +O=C(c1ccc2c(c1)[nH]c(=O)c1ccncc12)N1CCCC1 +COc1ccc2[nH]cc(C3CCN(C(=O)c4ccnnc4)CC3)c2c1 +Cc1ccc2nc(C3CCN(C(=O)C4CC4)C3)[nH]c2c1 +Cc1cc(C)cc(OCCNS(=O)(=O)c2cn[nH]c2)c1 +Fc1ccccc1OCCSc1nnc(Cn2cncn2)o1 +Cc1nccc(-c2cccc(NC(=O)c3ccnc(NC4CC4)c3)c2)n1 +CC1(C)CCCCC1CC(=O)NCc1csc(=O)[nH]1 +O=C(Cn1nc2c(cc1=O)CCCC2)NCC1CC2C=CC1C2 +CCc1noc(CC)c1CC(=O)N1CCC2CCCCC21 +CC(=O)c1cc(C(=O)NCCCc2ccc(F)cc2)cs1 +CCn1nccc1C(=O)Nc1nc(-c2ccco2)cs1 +Cc1[nH]nc(CCC(=O)NC2CCCc3nc(N(C)C)ncc32)c1C +CCN(Cc1ccccc1)Cc1cc(=O)c(O)cn1CCO +CN(C)S(=O)(=O)c1ccccc1CNC(=O)C1CCC1 +Cc1cnc(C(=O)Nc2ccc(F)c(F)c2F)cn1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)COC(=O)C1CC1 +Cc1nc(CN2CC3CN(c4ncccn4)CC3C2=O)cs1 +COc1ccc(C(=O)N2CCC(c3n[nH]c(C4CC4)n3)CC2)cc1F +CCc1cc(N2CCN(C(=O)C3CC3)CC2)nc2nncn12 +Cn1cc(CNC(=O)Nc2ccc3c(c2)OCO3)cn1 +Cn1nccc1NC(=O)C1(c2ccccc2)CCC1 +Cc1noc(NC(=O)c2sc(-c3ccccn3)nc2C)n1 +O=C1CCCc2occ(C(=O)N3CCCC(c4ccn[nH]4)C3)c21 +O=C1Cc2cc(NC(=O)Nc3cccc(Cl)c3)ccc2N1 +O=C(OCc1nc2ccccc2o1)c1cc2ccccc2c(=O)[nH]1 +O=C(CCc1ccc(F)c(F)c1)N1CCCCC1CCn1cccn1 +O=C(CSc1ccccn1)Nc1ccc(F)cc1C(F)(F)F +CCC(OC)C(=O)Nc1ccc(N2CCCCC2)c2ccncc12 +CCOC(=O)C(N)Cc1ncc(-c2ccncc2)o1 +C=CCn1c(SC(C)c2nnc(C)o2)nnc1-c1cccc(C)c1 +NC(=O)c1c(NC(=O)C2CC2)sc2c1CCCC2 +Cc1cccc(OCCCC(=O)NC(C)c2c(C)noc2C)c1 +CCc1c(C(=O)NC(C)c2c(C)noc2C)cnn1-c1ccccn1 +Cc1cccnc1CNC(=O)NCCCc1cccc(F)c1 +CCN(CC)S(=O)(=O)c1ccc(C#N)c(C(F)(F)F)c1 +Cc1nc(C2(NC(=O)c3ccc(F)cc3)CCCCC2)no1 +C=CCNC(=O)Nc1ccc2c(c1)CCCC(=O)N2 +COCC1CCCN1C(=O)NC1CCCN(Cc2ccccc2)C1=O +COc1cc(Cl)ccc1C(=O)OCc1ccccn1 +N#Cc1cccc(NC(=O)C2CN(C(=O)c3cccs3)C2)c1 +CCc1ccc(C(=O)N(C)Cc2nc3ccccc3n2C(F)F)o1 +O=C(Nc1nc(-c2ccc(F)c(F)c2)cs1)c1cscn1 +COc1ccc(C(=O)N=S(C)(=O)c2ccsc2)cc1 +CN(Cc1cnn(C)c1)C(=O)c1ccccc1C(=O)c1cccs1 +O=C(COC(=O)c1n[nH]c2ccccc12)Nc1ccc(F)cc1F +CCC(=O)N(Cc1cccnc1)c1ccc(F)cc1 +CN(Cc1nc2ccccc2[nH]1)C(=O)c1ccc(C(F)(F)F)cc1 +Cc1cc(OCC(=O)OCc2nnc(-c3ccco3)o2)ccc1Cl +Cc1nnc(CNC(=O)Cc2ccc3c(c2)CCCC3)n1C +CCOc1ccccc1OCC1NCCc2cc(OC)c(OC)cc21 +CSc1ncccc1C(=O)Nn1cnc2ccccc21 +CN(C(=O)c1cc(C(N)=O)cs1)C1CCCCC1 +C=C(C)CN(CC)C(=O)NC1CCN(C(=O)OCC)CC1 +COCC12CCCOC1CCN(S(=O)(=O)c1ccc(F)cc1)C2 +O=C(Nc1ccc(F)cc1)c1cccc(Oc2cnccn2)c1 +COc1cc(OC)c(C(=O)N2CCCCC2)cc1OC +O=C(c1cc(Cl)c2c(c1)OCO2)N(Cc1cccs1)C1CC1 +COc1c(F)cc(NC(=O)NCC(C)C)cc1F +O=C(NC1(c2ccccc2)CCC1)c1cc2ccccc2oc1=O +CCC1CCCCN1C(=O)c1cnc(COC)nc1N +COc1cc(C(=O)Nc2ccnn2CC(C)C)ccc1OC(C)C +Cc1ccc(CNC(=O)C(C)Cn2cc(Br)cn2)o1 +CCn1c(C)ccc(C(=O)NCC2COc3ccccc3C2)c1=O +COCC(O)c1cc(C)cc2c1OCCC2NC(=O)C(C)C +COc1ccc(-c2csc3ncnc(N(C)CCO)c23)cc1 +CN(C)C(=O)c1cccc(S(=O)(=O)N2CCOC(C)(C)C2)c1 +COc1ccc(-c2n[nH]c(SCc3cc(C)on3)n2)cc1 +COCc1nn(C)c2c1CN(S(=O)(=O)c1cccc(C#N)c1)CC2 +Cc1nn(C)c(C)c1CNC(=O)c1sc2nc[nH]c(=O)c2c1C +Cc1csc(NC(=O)c2ccnc(-n3ccnc3)c2)n1 +CC(C)CNC(=O)c1ccccc1NC(=O)C(C)(C)C +CCN(CC(O)c1ccc(C)cc1)C(=O)CSc1nncs1 +Oc1ccc(CNc2ccc3nccnc3c2)cc1 +Cc1cc(NC(=O)Cc2noc(C(=O)NCC(C)C)n2)no1 +Cn1c(=O)[nH]c(=O)c2c1ncn2CC(=O)Nc1cccc2ccccc12 +CC(C)Oc1ccc(CNC(=O)c2nccnc2N)cc1 +O=C(Nc1nncs1)C1CCCN(C(=O)NCc2ccccn2)C1 +CC(CNC(=O)C1CC1C)c1nc(-c2ccccc2)no1 +CCOC(=O)c1cc(-c2cnn(C)c2)cc2c1NCCC2 +COc1cccc2c(=O)c(NC(=O)NCc3ccco3)c[nH]c12 +CC(C)Oc1ccc(C(=O)Nc2nnc(-c3cccs3)o2)cc1 +CCc1ccc(N2C(=O)CC(c3nc4ccccc4s3)=C2N)cc1 +COc1ccccc1CNS(=O)(=O)c1cccc(C#N)c1 +COc1ccc(CNC(=O)c2cc(C)c(C)s2)cc1F +CC(C)NC(=O)CNc1cccc(NC(=O)c2ccccc2)c1 +COc1ccc(C(=O)N(C)Cc2ccccc2)c(O)c1 +Cc1nn(C)c(C)c1C(=O)Nc1cccc(Cl)c1C +CC(NC(=O)C1CC1(Cl)Cl)c1cccc(-n2cccn2)c1 +Cc1cccnc1NC(=O)CNC(=O)c1cccc(Br)c1 +Cc1cc(O)ccc1NC(=O)c1ccccc1Cl +COCCN1CCN(C(=O)C2(CCOC)CCC2)CC1=O +CCOC(=O)c1cc(Cl)cc(Br)c1N +CCOC(=O)c1c(C)oc(NC(=O)c2cc(C)on2)c1C#N +Cc1cc2ccccc2n1CCC(=O)NCC1CCOCC1 +CC(=O)c1cccc(NC(=O)c2ccc(NC(N)=O)cc2)c1 +COc1cccc(C(=O)Nc2ccc(C)c(N)c2)c1 +COc1cccc(-n2cc(CNC(=O)Nc3nccs3)nn2)c1 +COc1c(C(=O)NCc2cccc(C)c2)sc2ccc(F)cc12 +NC(=O)C1CCN(C(=O)c2c(F)cc(Br)cc2F)C1 +COc1cccc(OCC(=O)N2CCC3(CC2)OCCCO3)c1 +Cc1cccc(NCc2cnn3ccccc23)c1C +CC1CN(C(=O)Nc2ccc3c(c2)COC3)CC(C)O1 +CCOc1ccc(C(=O)N2CCC(CNC(=O)OC(C)(C)C)C2)cc1 +CNC(=O)CCC(C#N)c1ccc(OC(C)C)cc1 +O=C(NCc1nnc2n1CCC2)c1ccc(CN2CCCC2=O)cc1 +Cc1cc(NC(=O)CN(C)Cc2ccc(C(F)(F)F)cc2)on1 +CCC(NC(=O)c1cn(CC)c2ncccc12)c1ccc(OC)cc1 +Cc1cc(C(=O)NCC(Cc2ccc(F)cc2)C(N)=O)c(C)s1 +Cc1nc(SC(C)C(=O)NC2CCCC2)c(C#N)c(C)c1C +CC(=O)c1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1 +O=C(Cn1ccc2ccccc21)NCCc1ccncc1 +CCOc1ncccc1CNC(=O)NCc1ccc(F)cc1 +O=c1[nH]c(CN2CCCCC2CO)nc2ccccc12 +COCc1ccccc1NCC(=O)N1CCc2sccc2C1 +CSc1ccc(NC(=O)N(C)C(C)c2nc(C)sc2C)cc1 +CCc1nc2ccccc2n1CC(O)c1ccc(S(C)(=O)=O)cc1 +Cc1ccc(-n2nnnc2N2CCc3nc(C)ncc3C2)cc1 +COC(=O)c1ccccc1C(=O)Nc1cccc(C(F)(F)F)c1 +Cc1cc(C(=O)N2CCC(c3nc(C(C)C)no3)CC2)no1 +CCCCS(=O)(=O)N1CCC(C(=O)Nc2ccccc2C#N)CC1 +N#Cc1cccc(NC(=O)c2cccc(-n3cnnn3)c2)c1 +Cn1c(Nc2ccc3c(c2)CCC3)c(C#N)c(=O)n(C)c1=O +CC(C)CCNC(=O)c1ccc2c(=O)n(C3CCCC3)c(=O)[nH]c2c1 +Cc1ccc(C(=O)OCC(=O)NCCc2ccccc2)cc1 +Cc1ccc(NCC(O)c2ccco2)cc1Cl +CN(CCOc1ccccc1)C(=O)c1ccc(-n2ccnn2)cc1 +CS(=O)(=O)c1cc(C(=O)N2CCCC2)c(Cl)cc1Cl +Cc1ccc(CNC(=O)Nc2cc(C)on2)c(N(C)C)c1 +COc1ccc(Cl)cc1-c1noc(-c2ccncc2)n1 +COc1ccccc1NC(=O)c1ccc(NC(=O)NC2CCC2)cc1 +O=C(c1ccccc1Cl)N(Cc1ccc2cc[nH]c2c1)C1CC1 +Cc1c(NS(=O)(=O)C(C)C)c(C(=O)N(C)C)nn1C +CC(C)NC(=O)C(NS(=O)(=O)c1ccc2ccccc2c1)C(C)C +O=C(Cn1ccccc1=O)NCCNC(=O)c1ccc(O)cc1 +Cc1cc(C)nc(CNC(=O)CCc2nc(-c3ccccc3)no2)n1 +O=C(c1cnns1)N1CCN(c2cccc(Cl)c2)CC1 +CC(=O)NC(CC(=O)Oc1ccccc1C)c1ccc(C)cc1 +O=C(Nc1cccnc1-n1cncn1)c1c[nH]c2cccc(F)c12 +CN(C)C(=O)N1CCCC(C(=O)Nc2cc(Cl)cc(Cl)c2)C1 +CC(C)NC(=O)CC1OC(CNC(=O)c2ccco2)C(O)C1O +N#Cc1ccnc(Oc2ccc(Cl)c3cccnc23)c1 +CCC(CC(=O)NC(C)COC)c1ccc(C)cc1 +CS(=O)(=O)c1ccc(NC(=O)CSc2ccc(F)cc2)cc1 +CN(C)C(=O)c1ccccc1NC(=O)c1csc2c1CCCC2 +COc1ccc(C(=O)NC2CCC(=O)N(C)C2)c(O)c1 +CCc1c(-c2ccccc2)[nH]c2nc3c(c(=O)n(C)c(=O)n3C)n12 +COC(=O)N1CCC(NC(=O)Nc2ccccc2F)CC1 +CC(NC(=O)C1(c2cccc(C(F)(F)F)c2)CC1)c1ccncc1 +CCOCCNC(=O)Nc1nnc(-c2ccsc2)s1 +Clc1ccccc1-c1ncnn1Cc1nnc(C2CC2)n1C1CC1 +CNC(=O)C1(C)CN(C(=O)c2cnccn2)CCO1 +CCSc1ccccc1NC(=O)c1cccs1 +Cc1ccc(C(=O)NC(C)c2ccccc2)cc1N +Fc1ccc(C2NCCc3c2cc(F)c(Cl)c3F)cn1 +O=C(Nc1cc(F)ccc1SCC(F)F)c1ccoc1 +COc1ncccc1CNC(=O)N1CCCC1c1ccccc1C +CC(COC1CCOC1)NC(=O)NC(C)C1CCC1 +COCCNC(=O)Cc1csc(NC(=O)c2ccco2)n1 +Cc1nc2ccccc2n1CC(=O)NCCCn1ccnc1 +CCC1Nc2cc(Cl)c(Cl)cc2N(CC(=O)NC)C1=O +CCSc1cc(C(=O)NC(C)c2ccco2)ccn1 +O=C(c1cc(F)cc(Cl)c1O)N1CCc2cccc(F)c2C1 +Cn1ccnc1Sc1ccc(NC(=O)CCc2ccncc2)cc1 +CC(=O)N1CCN(c2nc(C(F)(F)F)nc3ccccc23)CC1 +COCCn1cc(NC(=O)NC2C3CCCCC32)cn1 +COCCN1CCN(C(=O)Nc2ccn(CCC(C)C)n2)CC1=O +CN(C)c1cccc(C2NCCc3c(O)ccc(F)c32)c1 +Nc1occ(-c2ccncc2)c1C(=O)c1ccc(F)cc1 +Cc1ccc(C(=O)NCCN2CCNC2=O)c(F)c1F +O=C1CCC2(CCCN(C(=O)c3cccs3)CC2)N1 +Cc1cc(NC(=O)CCCNC(=O)c2cccs2)no1 +Cn1cnnc1SCC(O)COc1ccccc1N +COc1ccc(Cl)cc1NC(=O)Nc1ccccn1 +COc1cc2nc(C(F)(F)F)n(N)c2cc1OC +Cc1nc2ccccc2n1CC(=O)NCCC(C)(C)C +COc1ccc(N)cc1NC(=O)C(C)Oc1c(C)cccc1C +Cc1cc(C)n(CC(=O)Nc2ncnc3[nH]c(C)c(C)c23)n1 +Cc1nc2ncnn2c(C)c1CCC(=O)NC(C)CN1CCOCC1 +N#Cc1ccc(N2CCN(C(=O)Oc3ccccc3F)CC2)c(F)c1 +OC(Cc1cccnc1)(c1ccccc1)c1ccccc1 +CC(Nc1ccc(Cl)cc1N)c1nncn1C +CCOC(=O)COc1cccc(NC(=O)c2c(F)cccc2F)c1 +C#CCOCC1CCCN(C(=O)C2COc3ccccc3O2)C1 +CCCc1oc(-c2ccc(OC)cc2OC)cc1CO +O=C(Cn1c2ccccc2c2cn[nH]c(=O)c21)NCc1ccco1 +CCCC1CN(C(C)=O)CC1NC(=O)c1ccc(Cl)cc1 +O=C1NCCNC1Cc1ccccc1-c1ccc(F)cc1 +N#Cc1cc(NCC2(CCO)CCOC2)ccc1C(F)(F)F +Cc1cc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2C)n(C)n1 +CCc1ccc(NC(=O)C(C)Sc2nnnn2C2CC2)cc1 +Cn1ccc2ccc(NC(=O)Cn3cccc(C(F)(F)F)c3=O)cc21 +Fc1cc2c(cc1Cl)C(c1ncccn1)NCC2 +COc1ccnc(NC(=O)CCc2ccc(C#N)cc2)c1 +O=C1CCC(COC(=O)CCc2ccc(-c3ccccc3)o2)N1 +CC(C)NC(=O)CCN1C(=O)c2ccccc2S1(=O)=O +CCCCNC(=O)Nc1cc(OC)cc(OC)c1 +CCN1CC2(CCC1=O)CCN(C(=O)C(C)Oc1ccccc1)CC2 +CCOCCCNC(=O)c1cc2sccc2n1C +CCN(CCc1ccccc1)C(=O)c1c[nH]c2cccc(F)c12 +CCCN(CCc1cccc(F)c1)C(=O)C1CCOCC1 +CC(=O)NCCSc1nnnn1-c1ccc(O)cc1 +Cc1c(NC(C)Cc2ccco2)cccc1C(N)=O +O=C(CSc1ccc(N2CCCCC2)nn1)Nc1cccc(F)c1 +Cc1cc(-c2nnc(CN3CCC(=O)Nc4ccccc43)o2)c(C)o1 +CC(NC(=O)C1CCCCC1)C(=O)Nc1ccc(F)cc1F +CSc1nc2sc3c(c2c(=O)n1N)CCC(C)C3 +COC(=O)C1CCCN1c1cc(F)ccc1OC +O=C(NC1CC(O)C(CO)C1)c1ccc2[nH]ccc2c1 +Cc1ccc(C(=O)N2CCN(Cc3ccccc3Cl)CC2)cc1 +COc1cccc(CNC(=O)N2CCN(S(C)(=O)=O)CC2)c1 +COc1cc(-c2noc(-c3cccc(Cl)c3)n2)ccn1 +CC(C(N)=O)N1CCN(Cc2cc3ccccc3s2)CC1 +CCOC(=O)c1nnsc1NC(=O)C(C)(C)C +COC(=O)C(NC(=O)C1CCOC1)c1ccccc1 +CNC(=O)C(NC(=O)COc1ccc(C#N)cc1)c1ccccc1 +CC(C)COc1cccc(CNC(=O)c2csnn2)c1 +CCOCCS(=O)(=O)Nc1ccc2c(c1)CCN2 +CNC(=O)c1ccc(OC)c(NCC(=O)NC2CC2)c1 +COC(=O)c1cc(-c2cn(C)nc2C)nc2c(Cl)c(C)nn12 +O=C(CNC(=O)C1CCCC1)Nc1cccc(F)c1F +CSc1ccc(C)c(C(=O)N2CCOCC2C2CC2)c1 +N#CC(CCCOc1ccccc1)C(=O)N1CCCCCC1 +CC(=O)Nc1ccccc1C(=O)Nc1c(C)cc(C)cc1C +NC(=O)Nc1cccc(NC(=O)c2ccn(-c3ccccc3)n2)c1 +NC(=O)C1CCN(C(=O)NCc2cc(F)ccc2Br)C1 +O=C(CS(=O)(=O)c1ccc(Cl)cc1)NCc1ccco1 +Cc1cc(C(=O)Nc2cc(C)n3nc(C(F)(F)F)nc3n2)c(C)o1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)C(C)C +O=C(c1cc[nH]c1)N1CCN(Cc2ccc(C(F)(F)F)cc2)CC1 +Cc1cccc(CN(C(=O)CNC(=O)c2ccsc2)C2CC2)c1 +COC(=O)c1cccc2c1CCCN2C(=O)C1CC1c1cnn(C)c1 +CCCN(CC1CC1)C(=O)NC(C)c1nnc2ccccn12 +CC(C)c1ccc(CNc2cccc(C(N)=O)c2)cc1 +COC(=O)Nc1nc(CC(=O)N2CCC(C)CC2)cs1 +COc1ccc(S(=O)(=O)NCCc2cccnc2)cc1OC +CCOC(=O)c1c(C)c(=O)cnc2c(C#N)cnn12 +COCCc1ccc(OC(=O)C2Cc3ccccc3C(=O)O2)cc1 +Cc1ccc(OCC2CN(C(=O)c3ccccc3Cl)CCO2)cc1 +COC(=O)CSc1nnc(Cn2ccc(C)n2)n1C +COc1cccc(C(=O)OC(C(N)=O)c2ccccc2)c1O +CN(CC1(c2ccc(Br)cc2)CC1)C(=O)C1CC1 +O=C(Nc1cc(N2CCCC2)ncn1)c1ccc(F)cc1F +Cc1ccc(NC(=O)CNC(=O)c2ccccc2F)c(Cl)c1 +c1ccc(Cn2nnnc2SCc2ccc(-n3cccn3)cc2)cc1 +CCS(=O)(=O)N1CCN(Cc2cn(C)nc2-c2ccncc2)CC1 +CCCN(CCO)C(=O)Nc1c(C)cc(Br)cc1C +Cc1nc2ccc(NC(=O)C3CC3)cc2c(=O)n1-c1ccc(F)cc1 +COCCC1NCCc2c(Br)cccc21 +COC(=O)C(CC(C)C)NC(=O)c1cccc(F)c1 +Cc1c(C2CC2(C)C)nc(N)c(C#N)c1-c1c[nH]cn1 +O=C1CCC2(CCN(C(=O)c3cc[nH]c3)CC2)CN1CC1CCCO1 +CCCCNC(=O)Nc1ccc(S(=O)(=O)N(C)C(C)C)cc1 +CC(=O)NCCNc1ccc2nnc(C(F)(F)F)n2n1 +COc1ccc(C(=O)Cn2cnc3sccc3c2=O)cc1Cl +CC(O)CC1COCCN1C(=O)NC(C)Cc1cccc(F)c1 +Cc1cccc(CNC(=O)NCc2ccnc(OC3CCC3)c2)n1 +COc1ccc(-c2nc3c(OC)cccn3c2C#N)cc1F +O=C1CCC(C(=O)Nc2ccc(-n3ncc4ccccc43)cc2)N1 +O=C(Nc1cccc(-c2ccn[nH]2)c1)c1cc2ccccc2c(=O)[nH]1 +COc1cc2ncnc(N3CCCC3)c2cc1OC +COc1ccc(Oc2ncnc(N3CCCCC3)c2N)cc1 +Cn1c(=O)ccn(CC(=O)Nc2nc(CC(N)=O)cs2)c1=O +CCOC(=O)c1cccc(NC(=O)c2ccc3c(c2)OCO3)c1 +O=C(NCC(O)COc1ccc(F)cc1)c1ccccn1 +CN(C)c1nc(N)nc(CS(=O)(=O)c2ccccc2F)n1 +CN(C)c1c(Cl)cccc1NS(=O)(=O)c1cn[nH]c1 +O=C(Cc1ccccc1)NC1CNc2ccccc2C1 +Cc1cccc(Nc2ncnc3c2cnn3C)c1C +O=C(OCc1cccnc1)C1CCN(c2cc(F)cc(F)c2)C1=O +COc1ccc(C(C)N(C)C(=O)c2ccc(C)cc2)cc1 +O=C1CCN(S(=O)(=O)Cc2ccccc2)CCN1 +OCc1ccc(-c2nccn2-c2cccc(C(F)(F)F)c2F)o1 +O=C(Cn1c(=O)cnc2ccccc21)OCC(=O)N1CCCCCC1 +CCOC(=O)c1cnn(CC(=O)NC2CCCCC2)c1 +CCOc1ccc(S(=O)(=O)N2CCC(C#N)CC2)cc1 +CCOc1ncc(C(=O)NCC(C)(O)C(C)C)cc1Cl +COc1ccc(OC)c2c(=O)c3ccccc3[nH]c12 +CCCOc1cc(CO)cc2c1OCC(=O)N2CC(=O)OC +COC(=O)c1ccccc1C1CCN(C(=O)OC(C)(C)C)CC1 +CCCS(=O)(=O)N1CCC(N2CCOC(C)C2)CC1 +CCC(CO)NS(=O)(=O)c1cc(OC)c(C)cc1OC +CC(C)NC(=O)Nc1ccc(C(=O)N2CCOC(C)C2)cc1 +CC(C)CCOCCS(=O)(=O)c1nncn1C +CC(CC(=O)N(C)CC(O)C1CC1)c1ccc(F)cc1 +OC(c1nnc(-c2ccccc2)o1)c1ccccc1OC(F)F +Cc1cccc(S(=O)(=O)NCc2ncn(C)n2)c1Br +CC(C(=O)Nc1ccc(F)c(F)c1)c1cccs1 +CS(=O)(=O)NCC(=O)Nc1ccccc1N1CCCCC1 +N#Cc1cccc(C(=O)OCCNc2cccnn2)c1 +Cc1ccc(NC(=O)c2cn(C)nc2-c2ccc(F)cc2F)c(O)c1 +CCc1ccc(S(=O)(=O)NCC(O)c2ccc3c(c2)CCO3)cc1 +COc1ccc(-c2nc(CN3CCCS3(=O)=O)co2)cc1 +O=C(Nc1cn[nH]c1)N1CCCC(NS(=O)(=O)c2ccccc2)C1 +CSc1ccc(C)c(NC(=O)CN2CCCCC2=O)c1 +CCc1cccc(NC(=O)Cc2csc(=NS(C)(=O)=O)[nH]2)c1 +Cn1cc(C2CCCN2C(=O)c2sccc2C#N)cn1 +CCC(C)C(C)NC(=O)NCC(O)c1cccs1 +CC(C)C(=O)N1CCOC(c2ccc(F)cc2)C1 +CC(C)(C(=O)NCCC(=O)N1CCCCC1)c1cccc(Cl)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1ccc(Cl)cc1 +O=C(NCC1(c2ccccc2)CC1)C1CCCN(c2ncccn2)C1 +O=C(NC1CCOCC1)NC1CCOC(C2CC2)C1 +CN(C)S(=O)(=O)N1CCOc2cc(N)ccc21 +CN(C)C(=O)CN(C)C(=O)C(C)(C)c1cccc(C(F)(F)F)c1 +CCOc1ccc(CC(=O)Nc2cccc(NC(C)=O)c2)cc1 +CCN(Cc1ccncc1)C(=O)c1cc2ccncc2cn1 +CCNc1nc(C)cc(N2CCN(S(C)(=O)=O)CC2)n1 +COc1ccc(Cl)cc1NC(=O)CCC(N)=O +Cc1cccc(CN2CCN(C(=O)COCc3nc(C)no3)CC2)c1 +OC1=Nc2c(cnn2Cc2ccccc2)C(c2ccc(O)cc2)C1 +Cc1nccc(CNC(=O)C(C)(C)c2cccc(C(F)(F)F)c2)n1 +O=C(Cn1c(=O)oc2ccccc21)Nc1cccnc1-n1cccn1 +Cc1ccc(C)c(C(=O)CCC(=O)Nc2c(C)cccc2C)c1 +CC(=O)Nc1cccc(NC(=O)NC(C)c2ccc(F)cc2Cl)c1 +COc1ccc(-c2ccc3c(c2)c(C)nc(=O)n3C)cc1 +COc1ccc(C)c2c1N(C(=O)c1ccc(C)nc1)CCC2 +COc1cc(CNC(=O)Nc2cc(C#N)ccc2C)ccn1 +CC1(CNC(=O)c2cccc(NC(=O)C3CCCCC3)c2)CCCO1 +COC(=O)CN(Cc1cc(F)ccc1Br)C(C)C +Fc1cc(F)c2c(c1)CCCN2Cc1nc(-c2ccco2)no1 +CCc1cc(NC(=O)c2cccc3c2ccn3C)[nH]n1 +CC(CCc1ccccc1)NC(=O)c1ccccn1 +Cc1ccc(C(=O)NCCNc2ccc(-n3ccc(C)n3)nn2)cc1 +O=C1Nc2cc(Cl)ccc2OC1c1ccccc1 +O=C(c1ccsc1)N1CCCC(OCc2nc(C3CC3)no2)C1 +O=C(C1CCC1)N1CCN(c2ccc(C(F)(F)F)cn2)CC1 +Cc1noc(C)c1S(=O)(=O)N(C)C(C)c1cccs1 +Nc1cccc(C(=O)NCc2ccc3c(c2)CCO3)c1 +COc1ccccc1NC(=O)NCc1cc(-c2ccccn2)n(C)n1 +COc1cc(CNC(=O)Nc2ccc(OC(C)C)cc2F)ccc1O +CC1CCCC(NC(=O)c2ccc(N3CCOC3=O)cc2)C1C +COc1cccc(NC2C(=O)Nc3cc(F)ccc32)c1 +COc1cc(C)c(C)cc1S(=O)(=O)n1cnc2ccccc21 +COC(=O)CCNS(=O)(=O)c1ccc(Cl)cc1F +CCC(C)n1cc(C(N)=O)c(=O)c2c(N)cccc21 +CCCn1nc(C(=O)NC2CCCC2Cc2ccccc2)ccc1=O +Cc1c(Br)cnc(F)c1Br +Cc1cc(NC(=O)COc2ccc3c(c2)[nH]c2ccccc23)no1 +CC(C)CNC(=O)N1CCN(c2ncnc3sccc23)CC1 +CC(=O)c1ccc(NC(=O)CNc2ccccc2)cc1 +Cc1csc(CNC(=O)c2cc(Br)cn2C2CC2)n1 +COCC(=O)N(C)Cc1ccc(OC)c(OC)c1 +CCOC(=O)N1CCC(NC(=O)c2cccc(N(C)C)c2)CC1 +COc1cc(C#N)ccc1OC(=O)CCSc1ccccc1 +Cc1nc(CC(=O)Nc2cccc(OCC(=O)N(C)C)c2)cs1 +Cc1nc(CN2CC3(CCN(C(=O)NC(C)C)C3)CC2=O)cs1 +CC(C)CNC(=O)NCC(O)c1cccc(F)c1 +COCCCCNc1c(C)cc(N(C)C)cc1C +N#CCOc1cccc(CC(=O)NCC2(c3ccccc3)CCC2)c1 +O=C(NCC(O)c1ccc(F)cc1)C1CCOCC1 +Nc1cccc2c1nc(-c1ccccc1F)n2CC(O)CO +CCC(C)NC(=O)NCCNC(=O)c1ccc(Br)cc1 +CC(C)(C)c1nc(CN(c2ccc(C#N)cc2)S(C)(=O)=O)cs1 +CN(Cc1ccncc1)C(=O)Nc1ccc(Cl)c(F)c1 +COCc1ccc(CNS(=O)(=O)c2ccccc2F)cc1 +CCN1CCN(C(=O)C(C)Oc2cccc(N)c2)CC1 +Cc1ccc2c(c1)cc(C(=O)N1CCOCC1)n2C +CCCc1noc(Cn2c(=O)oc3cc(Cl)ccc32)n1 +CCc1ccc(N(CC(=O)N(C)C)S(C)(=O)=O)cc1 +CCOC(=O)C1CCCN(C(=O)NCCNC(C)=O)C1 +COc1cccc(CC(NC(C)=O)C(=O)Nc2ccccn2)c1 +CSc1ccccc1C(=O)N(CCO)C1CC1 +CCn1c(SCCNS(C)(=O)=O)nnc1C1CC1 +Cc1nc(CN(C)C(=O)c2cnns2)cs1 +Cc1ccc(C(C)NC(=O)c2cccc(N)c2)s1 +COc1ccccc1OCc1cc(C(=O)N2CCC(OC)CC2)no1 +CCN(CC(=O)NC)S(=O)(=O)c1c(C)cc(OC)cc1C +Cc1ccc(C(=O)N2CCC(c3nncn3-c3ccccc3)CC2)cn1 +O=S(=O)(c1ccc(CNc2cccc(Cl)c2)cc1)C(F)F +Cc1ccc(OCC(O)Cn2cnc3cc(F)ccc3c2=O)cc1 +COCc1ccc(C(=O)NC2(C(N)=O)CCCC2)o1 +CC(C)OCCCNC(=O)Nc1ccn(-c2ncccc2Cl)n1 +Cc1cc(C)n(C2CCCN(C(=O)c3cc(C4CC4)on3)C2)n1 +CCCC1CN(C(=O)C(CC(C)C)N2CCCCC2=O)CCO1 +O=C(NCCNc1ncccn1)c1cncc(Br)c1 +Cc1cc(N)c2ccnc(C(=O)N3CCCCCC3)c2c1 +COC(=O)c1nnn(CCCOc2ccc(Cl)cc2)c1N +CNC(=O)c1ccc(Cl)cc1NC(=O)COc1cccc(C)c1 +CCN1C(=O)Cc2cc(NC(=O)c3ccccc3F)ccc21 +COC(=O)c1ccc(C(=O)N2CCCC2c2nc3ccccc3[nH]2)cc1 +Cc1cc(-c2ccc(S(=O)(=O)NCc3ccccc3C)s2)on1 +COc1ccccc1C(=O)OCC(=O)NCc1ccccc1Cl +COc1cccc(COc2nc(C(C)C)nc(C)c2CCO)c1 +CC(C)NC(=O)C1CC2CN(Cc3cnn(C)c3)CC1O2 +CN(Cc1ccc(S(=O)(=O)N(C)C)o1)c1ccc2ccccc2c1 +Cc1ccc(F)c(NC(=O)CCn2cnc3sccc3c2=O)c1 +Cc1c(NC(=O)c2ccccc2)cccc1-n1cnnn1 +COCc1nc(NC(C)CCc2ccco2)c2cnn(C)c2n1 +CC(=O)N1CCN(C(=O)c2cn(C)c3ccccc23)CC1 +CCCOc1ccc(C(=O)Nc2cccn(C)c2=O)cc1OCC +CCc1cccc(CC)c1NC(=O)Cn1nnnc1CC +COc1ccccc1OC(C)C(=O)Nc1ccc(C)c2ncccc12 +Cc1nc(CSc2nncn2C2CC2)nc2ccccc12 +N#Cc1ccc(C(=O)OCCOCC(F)(F)F)cc1 +CC(C)CCCNc1ccccc1S(N)(=O)=O +CC(C)=CCc1c(O)cc(O)c2c(=O)cc(C)oc12 +O=C(NCc1nnc2n1CCC2)Nc1ccc(Cl)cc1F +COc1ccc(C(=O)Nc2nnc(-c3ccc4c(c3)OCO4)o2)cc1 +COc1cc(OC)cc(C(=O)Nc2cc(OC)ccc2F)c1 +Cc1cc(NC(=O)c2ccco2)sc1C(=O)OC1CCOC1=O +CN1CCN(C(=O)c2cc3ccccc3oc2=O)CC1=O +CC(=O)N1CCc2c(nc(N(C)C)nc2NC2CCCCCC2)C1 +Cn1cc(C2CN(Cc3cccn3Cc3cccs3)CCO2)cn1 +CCCCN(C)C(=O)NCCNC(=O)c1ccco1 +CN(Cc1ccc(C(N)=O)cc1)c1cnc2ccccc2n1 +Fc1cc2sc(NCCN3CCOCC3)nc2cc1Cl +CCCCc1nnc(NC(=O)c2ccc(N3CCOCC3)nc2)s1 +COc1ccc(CNc2ccc(NC(C)=O)cc2)c(OC)c1 +CCC(NC(=O)c1ccc(F)c(C)c1)c1nccs1 +COC(=O)CC(Cc1cccc(Cl)c1)C(=O)OC +COc1ccc(CNc2cccnc2)c(OC)c1OC +COc1ccccc1C1NC(=O)c2cccc(C)c2N1 +CNC(=O)c1cc(NC(=O)NC(C)(CO)C2CC2)ccc1F +CC1CN(C(=O)c2ccc(Cn3cnnn3)cc2)CC1(O)C1CCC1 +Cc1cccc(CNC(=O)NCCCN2CCCCCC2=O)c1 +CCN(CC)C(=O)C1CCN(Cc2cnc(C(C)(C)C)s2)CC1 +Cc1noc(C)c1C(=O)N1CCOC2C(Oc3ccccn3)CCC21 +Fc1cc(F)c2c(c1)CCNC2c1ccncc1Cl +COC(=O)CC(NC(=O)c1ccccn1)c1ccc(Cl)cc1 +Cc1cc(=O)c(C(=O)N2CC(C)c3ccccc32)nn1-c1ccccc1 +NC(=O)NCc1ccc(C(=O)OCC(=O)C2=NC=CC2)cc1 +Cc1nnsc1C(=O)OCc1cc(-c2ccccc2)on1 +O=C(NCCc1ccccc1)c1cc(-c2cccnc2)on1 +CC(=O)c1nn(-c2cccc(C)c2)c2nc3ccccc3n12 +Nc1c(-c2ccc(Cl)cc2)noc1C(=O)N1CCCC1 +COc1ccc(N)c(C(=O)N2CC(C)CC(C)C2)c1 +Cc1[nH]ncc1C(=O)NC(Cc1ccccc1)C(=O)Nc1ccccc1 +CC(=O)c1ccc(OC(=O)C2(c3cccc(F)c3)CCOCC2)cc1 +O=C(c1ccc(N2CCCCS2(=O)=O)cc1)N1CCOCC1 +CCc1c(C#N)cc(C(C)=O)n1Cc1ccccc1 +Nc1ccc2c(c1)N(CC(O)CO)C(=O)C(Cc1ccccc1)O2 +COCC(=O)Nc1ccc(S(=O)(=O)NC(C)=O)cc1 +CCOC(=O)C(c1c[nH]c2ccccc12)C(F)(F)F +CCOC(=O)Cn1c(=O)c2c(OC)c(C)cnc2n(C)c1=O +Cc1noc(CNc2ccccc2C(=O)N2CCCCC2)n1 +CC(COc1ccccc1C(F)(F)F)NC(=O)Cc1ccc[nH]1 +CC(=O)N1CCc2cc(NC(=O)NC(C)C(C)C)ccc21 +CCN1CCN(C(=O)C(C)Sc2nnc(-c3ccccc3)o2)CC1 +O=C1CN(C(=O)c2ccncc2F)C2CCCCC2N1 +CCOC(=O)c1cnc2nc(C(F)(F)F)nn2c1N +CCN(CC1CC1)C(=O)Nc1ccc(C)c(C(N)=O)c1 +CC(C)N(Cc1ccccc1)C(=O)CCS(=O)(=O)c1ccccc1 +O=C(NCC(O)C1CCCC1)C1COc2ccccc21 +CCSc1ncc2c(=O)n(CC(=O)N3CCC(C)CC3)cnc2n1 +Cc1cc(C(=O)N2CCCC3(CCCC(=O)N3C)C2)c(C)o1 +Fc1cccc(NCCCOC2CCOCC2)n1 +CCCOc1cc(C)ccc1NCc1ccncc1 +COc1ccccc1NC(=O)N(CC1CCOC1)C1CC1 +Nc1cc(C(=O)NCC(F)(F)F)ccc1Cl +COCc1cccc(CNS(=O)(=O)c2ccc(C)cc2C)c1 +Cn1cnnc1S(=O)(=O)Cc1ccc(C#N)cc1 +CC(C)N1CC(CO)OC1c1c(F)cccc1Cl +O=c1c2ccccc2ncn1Cc1noc(C2CCCCC2)n1 +CN1C(=O)C(c2ccccc2)NC(=O)c2ccccc21 +CSc1ccc(C(=O)N(C(C)C)C(C)C)cn1 +O=C(Nc1cc[nH]n1)c1c[nH]nc1-c1ccccc1 +Cc1nc(CC(=O)C(C#N)c2ccccn2)cs1 +Fc1ccc(NCc2n[nH]nc2-c2ccccc2)cc1 +Cn1c(C(N)c2ccncc2)nc2cc(N)ccc21 +Cn1c(CNC(C)(C)c2ccc(Cl)cc2)nnc1C1CC1 +CCN1CCOC(CC(=O)Nc2ccc(C)c(C)c2)C1=O +Cc1cccc(C)c1OCCC(=O)NC1CCC(O)CC1 +c1ccc2c(c1)N(Cc1ccno1)CCCN2Cc1ccno1 +CN1CCN(C(=O)Cc2c(F)cccc2F)c2cc(F)ccc21 +COc1ccc(-c2cccc(Cl)c2C)n2nc(N)nc12 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1ccc(C(N)=O)cc1 +Cc1[nH]nc(C(=O)Nc2ccc(Br)cc2Cl)c1N +Fc1ccc(-c2ccc(CNn3cnnc3)o2)cc1 +Cc1cc(C)c(C(=O)NCC2(N3CCOCC3)CCCCC2)c(=O)[nH]1 +CCc1cccc(C)c1NC(=O)CNc1cccc(OC)c1 +CN(C(=O)CCN1CCCC1=O)c1cccc2ncccc12 +NC(=O)CNC(=O)CCCNC(=O)c1ccsc1 +Cc1cn(C2CC(O)C(O)C(CO)O2)c(=O)[nH]c1=O +COc1cccc(C(=O)Nc2cccc(F)c2C#N)c1OC +O=C(NCC1CC=CCC1)N1CCN(Cc2ccon2)CC1 +COc1ccc(OCCN(C)C(=O)c2cnccn2)cc1 +COc1ccnc(NC(=O)c2ccc(Br)c(Cl)c2)c1 +CCC1CCCC(NC(=O)N2CCn3c(nnc3C(F)(F)F)C2)C1 +COC(=O)C(NC(=O)c1ccc(C)cn1)c1ccc(Cl)c(F)c1 +Cc1ccccc1CC(=O)N1CCCc2c(cnn2C)C1 +COc1ccccc1NC(=O)C(C)NC(C)c1ccc(F)c(F)c1 +CC1CCN(c2nc(-c3ccc(N4CCCC4=O)cc3)cs2)CC1 +O=C(Cc1cccc(O)c1)N1CCC(c2cccc(F)c2)C1 +Cn1nnc2c(N3CC(C(=O)NC4CC4)C3)ncnc21 +CCc1n[nH]c(SCCn2c(=O)oc3ccccc32)n1 +CC(C)n1nccc1NC(=O)NCCCN1CCOCC1 +CSc1cccc(NC(=O)CCNC(=O)Cc2ccccc2)c1 +O=S(=O)(NCC1CCCc2ccccc21)N1CCOCC1 +Cc1nc(C(=O)N(C)C)nn1-c1c(Cl)cccc1Cl +Cc1ccccc1CC(=O)NCc1noc(C(C)C)n1 +CC(C)(C)NC(=O)CNC(=O)CSc1nccc2ccccc12 +CC(=O)Oc1ccc(C(C)(C)c2ccc(OC(C)=O)cc2)cc1 +Cc1cc(NC(=O)CSc2ccc(-c3cccnc3)nn2)no1 +CN(C(=O)Cn1nnc(-c2ccc(Br)cc2)n1)C1CC1 +Cc1ccc(C(=O)N2CCCC2c2ccncc2)cc1 +Nc1cc(Cl)ccc1N1CCc2sccc2C1 +NC(=O)c1cccc(CSc2ccccc2F)c1 +O=C1C2CCN(Cc3ccccn3)CC2OCCN1c1ccsc1 +N#Cc1c(-c2cccs2)nc2sc(C3CC3)nn12 +CCCCCC(C)NC(=O)NC(C)C(=O)N1CCCCC1 +COC(=O)C1CCCC1NC(=O)Nc1nnc(CC(C)C)s1 +O=C(c1cc2ccccc2o1)N(Cc1ccccn1)C1CC1 +COc1cccc(-n2nnc(CO)c2-c2ccc(C)c(C)c2)c1 +Cc1nc2ccc(C(=O)Nc3ccncc3)cc2nc1C +COc1cc(N)ccc1NS(=O)(=O)c1cccs1 +COc1cc(C)c(C(=O)NCC(C)(O)c2ccsc2)cc1OC +O=C(COc1ccc(Oc2ccccc2)cc1)n1ccnc1 +Cc1cc(C(=O)NCc2nnc3n2CCC3)c(C)o1 +COCCCN(C)C(=O)c1ccc2c(c1)CCCC2 +COCCN(Cc1ccoc1)C(=O)c1ccc2ccccc2c1 +CS(=O)(=O)c1ccc2c(c1)nc(N1CCC(O)CC1)c1nccn12 +CC(C)(C)c1noc(CN2C(=O)CCc3ccccc32)n1 +O=C(c1ccccn1)N1CCC2COC(CNc3ncccn3)C2C1 +COCCCC(=O)Nc1ccc(Cn2ccnc2C)cc1 +O=C(Nc1nnc(-c2ccc3c(c2)OCO3)o1)C1CCCCC1 +Cc1nc(C(=O)N2CCN(C(=O)C(C)(C)c3ccccc3)CC2)c[nH]1 +Cc1oc2cc3oc(=O)c(CC(=O)NC(C)CO)c(C)c3cc2c1C +COC(=O)NCCC(=O)N1CCCC(C)(C)c2ccccc21 +COC(=O)c1cc(CNC(=O)c2cc(-c3ccccc3)on2)oc1C +O=C(Cn1cnc2scc(-c3cccs3)c2c1=O)NCCO +COc1ccnc(NC(=O)COc2ccc(C(C)=O)cc2)c1 +Cc1cnc(C)c(NS(=O)(=O)c2ccc(N)cc2)n1 +COc1cc(OC)c(NC(=O)c2sccc2C#N)cc1F +CN(C(=O)Cc1cn2ccccc2n1)c1ccc(F)cc1 +CNC(=O)c1cccc(NCc2nc(-c3ccccc3)no2)c1C +Cn1nnnc1SCC(=O)N(Cc1ccsc1)C1CC1 +COC(=O)C(C)N1CCN(C(=O)c2c(Cl)cccc2Cl)CC1 +CN(Cc1ccccc1N)S(=O)(=O)CC1CCCCC1 +CS(=O)(=O)Nc1ccccc1NC(=O)Cc1ccccc1F +O=C(CCc1ccccc1F)Nc1ccc2c(c1)C(=O)NCC2 +CCn1nc(C)cc1NC(=O)CCS(=O)(=O)c1ccc(C)cc1 +C=CCSc1c(CCC)cnc2c1c(=O)n(C)c(=O)n2C +CC(C)CCOCCNc1cccc(F)c1C#N +O=S(=O)(C1CCOC1)N1CCc2cc(Cl)cc(Cl)c2C1 +COc1ccc(Br)c(CN2CCOC3(CCC3)C2)c1 +CCCNC(=O)c1cccc(NC(=O)c2ccncc2F)c1 +Nc1c(Nc2cccnc2)ncnc1Nc1cccc2cccnc12 +Cn1cc(C2CCCN2C(=O)c2cc3cc(F)ccc3[nH]2)cn1 +CCC(=O)Nc1cccc(NC(=O)Cc2ccccc2)c1 +CNc1nc(-c2sc(CC(C)C)nc2COC)cs1 +CCS(=O)(=O)NCC#Cc1ccc(N2CCCCC2=O)cc1 +CCC(=O)c1ccc(SCC(=O)N(C)CCC#N)cc1 +CNC(=O)c1ccc(OCc2ccccc2F)c(N)c1 +Cc1cc(C)c(S(=O)(=O)NCC(=O)NC(C)C)c(C)c1 +CN(C)S(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +NC(=O)c1cccc(NC(=O)c2cc3c(cc2Cl)OCCO3)c1 +CCCN1C(=O)C(C)(CC)N(C)c2ccc(N)cc21 +CCc1c(C(=O)Nc2ccc(F)cc2F)[nH]c(C)c1C(C)=O +C#CCNC(=O)c1cc2c(F)cc(Br)cc2[nH]1 +O=C(NCCN1CCOCC1)c1ccc(=O)n(-c2ccccc2)c1 +Cc1cc(C)c(NCc2ccc(O)c(F)c2)c(C)c1 +CC(=O)c1nc2ccccc2n1Cc1ccccc1F +Cc1ccc2c(c1)OCC(=O)N2Cc1cccc(F)c1 +COc1ccc(-c2cc(N)c(=O)n(CCC(C)C)n2)cc1C +COc1ccc(C(=O)CN2CC(C)OC(C)C2)c2ccccc12 +Cc1ccc(C(C)(C)C)cc1C(=O)Cn1cc(N)cn1 +Cc1cccc(C(=O)Nc2ccc3c(c2)COC3)n1 +CCOCC1CCCN(C(=O)C2CCCN(C(=O)C(C)CC)C2)C1 +CSc1nnc(-c2ccc(OC(F)F)cc2)o1 +CC1CCC(NC(=O)C2CCN(C(=O)N(C)C)CC2)CC1 +O=C(NCc1ccoc1)Nc1ccc(Cl)cc1Cl +CCC(NC(=O)c1ccc(-n2ccnn2)cc1)c1ccc(OC)cc1 +COC(=O)c1cnc(Nc2nc(C)c3cc(C)c(C)cc3n2)nc1C +COCc1cc(C(=O)Nc2ccc(OC)c3ncccc23)ccc1F +CCC(C)N(Cc1ccsc1)C(=O)c1ccnn1CC +CCc1ccccc1NC(=O)N1CCN(c2ccc(C)nn2)CC1 +N#Cc1cccc(C(=O)Oc2cccc3[nH]ncc23)c1 +COCC(=O)NC(C(=O)Nc1ccc(C)cn1)C(C)C +Cc1cnn(CC2CCCN2C(=O)c2n[nH]c(=O)c3ccccc23)c1 +COc1ccc(C#CCNC(=O)NCc2ccc(OC)cc2)cc1 +O=C(OCC(=O)N1CCc2ccccc21)C1CCOCC1 +O=C(CNS(=O)(=O)c1ccc(Cl)cc1)NCc1ccncc1 +N#Cc1ccc(C(=O)Nc2ccccc2-n2cnnn2)cc1 +COc1cccc(C(O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 +Cn1c(=O)[nH]c(=O)c2c1nc1n2CC(O)CN1c1ccccc1 +CCOC(=O)C(C)(C)N(C)Cc1sc(N(C)C)nc1C +O=C(Nc1c[nH]ccc1=O)c1cn(Cc2cccs2)nn1 +Cc1ccccc1-n1cnnc1SCC(=O)N1CC(C)OC(C)C1 +O=C(NCc1cc(Br)cs1)Nc1ccncc1F +CC(NC(=O)c1cccs1)C(=O)NCCCC(N)=O +CCC1CN(C(=O)C2CCOC2)c2ccccc2O1 +Cc1cc(C2CCCN2C(=O)c2cnc3c(cnn3C(C)C)c2)on1 +Cc1ccccc1CN(C)C(=O)Nc1cnn(C)c1 +NC(=O)Nc1cccc(C(=O)N2CCc3cc(F)ccc3C2)c1 +COCC(C)OC(=O)Cc1nc(-c2ccccc2)oc1C +COc1ccc(NC(=O)CSc2nc(C)c(C)c(=O)[nH]2)c(OC)c1 +CC(C)CCC(=O)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1 +O=C(COCc1cc(-c2ccc(F)cc2)on1)Nc1ccccn1 +C=CCn1c(C)nnc1SCC(=O)Nc1nnc(CC)s1 +CCc1onc(C)c1NC(=O)N(CCOC)Cc1ccc(C)o1 +NC(=O)c1ccc(CNC(=O)C2CCCN2C(=O)c2cccs2)o1 +COc1ccc(CN2C(=O)COc3nc(C#CCO)ccc32)cc1 +O=C(COc1ccc(F)cc1)Nc1ccccc1F +COc1cc(NCC2CCCO2)nc(C(C)(C)C)n1 +CCOC(=O)CCC1(Cc2ccccc2)OCCO1 +CCNC(=O)COc1ccc(NC(=O)Cc2cccc(F)c2)cc1 +COCCNC(=O)c1cc2c(=O)n3cc(C)ccc3nc2n1C +COC(=O)CCCNC(=O)c1ccccc1N1CCCCC1 +CC(C)(C)c1ccc(O)c(NC(=O)c2cc[nH]n2)c1 +CCCCN(c1ccccc1)S(=O)(=O)c1ccc(C(N)=O)cc1 +Fc1cncc(C2NCCc3cc4c(cc32)OCC4)c1 +CNc1cc(C(=O)N(Cc2ccsc2)C2CC2)ccn1 +Cc1ccc(C(N)=O)cc1NC(=O)N(C)Cc1cnn(C)c1 +Cc1ncsc1CNC(=O)c1ccc(N)cc1N +CC(CN1CCOCC1)NS(=O)(=O)c1cnn(C)c1 +CN(C(=O)C1CCCO1)C(C#N)c1ccc(C(C)(C)C)cc1 +Cc1ccc(CC(=O)Nc2ccc(S(N)(=O)=O)c(C)c2)cc1 +CCC(NC(=O)N1CCN(CCOC)C(=O)C1)c1c(C)noc1C +CCc1nc(CC(=O)Nc2cccnc2-n2ccnc2C)cs1 +Cc1ccc(C(=O)CNC(=O)c2cccc(C)c2)cc1 +CN(C)C(=O)CN(C)C(=O)c1ccc(Oc2ccccc2)cc1 +O=C(CCc1ccc2c(c1)OCO2)Nc1nc[nH]n1 +N#Cc1ccc(-c2ccccc2)n(CC(N)=O)c1=O +CC(C)=CC(=O)Oc1ccc(NC(=O)c2ccco2)cc1 +CC1CCCN(S(=O)(=O)NC2CCCCC2)C1 +Cc1nc2ccccc2c(=O)n1-c1ccc(C(=O)N(C)C(C)C)cc1 +C=CCNS(=O)(=O)c1cc(C)c(OCC)cc1C +O=C(NCc1cccs1)c1cccc(N2CCOC2=O)c1 +NC(=O)CC1CCN(c2ncccc2Br)CC1 +Cc1cc2cc(NC(=O)c3cn(C)nc3-c3cccnc3)ccc2[nH]1 +Cc1csc(CCC(O)c2ccc(Br)cc2)n1 +CCC(C)NC(=O)c1cc(-c2cn[nH]c2)nc2cc(OC)ccc12 +CCCC(=O)NC(CN1CCOCC1)c1ccccc1 +COC(=O)C(O)(CC(=O)Nc1ccc(F)c(Cl)c1)C(F)(F)F +Nc1ccc(C(=O)NCC(F)(F)F)c(Cl)c1 +CCCCNC(=O)Nc1cccc(CN2CCOC2=O)c1 +Cc1n[nH]c(C)c1CC(C)C(=O)N(C)CCc1ccccc1 +CC(C(=O)OC(C)(C)C)N1CCN(C(C)C(=O)N2CCCC2)CC1 +Cc1ccc(O)c(C(=O)N(C)CCC(F)(F)F)c1 +Cc1cccc(C(=O)Nc2ccc(NC(=O)C3CC3)cc2)c1 +C=CCNc1nnc(SCc2cn3c(C)cccc3n2)s1 +CCN(Cc1ccco1)C(=O)Nc1c(F)cccc1F +CN(C)C(=O)C1CCCN1c1cccc(F)c1C#N +CC(C)n1nccc1C(=O)NCCN1CCc2ccccc21 +Cc1noc2ncn(CC(=O)NCc3cccc(F)c3)c(=O)c12 +CC1CN(C(C)c2nc(C3CC3)no2)CC(C)O1 +COC(=O)c1cn(Cc2nnc(-c3cc(C)cc(C)c3)o2)nn1 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1cc(C(C)(C)C)no1 +Cn1cnnc1-c1ccccc1NC(=O)c1ccc(C(F)(F)F)cc1 +Cc1cc(C)n(NC(=O)CCS(=O)(=O)c2ccccc2)c(=O)c1 +COc1ccc(-n2ccnc2SCC(=O)NC(C)C)cc1 +COC(=O)c1ccc(C(=O)Nc2cc3c(cc2Cl)OCO3)cc1 +O=C(Nc1cc(-c2ccco2)nn1CCO)c1ccco1 +CCC(C)OC(=O)c1cnn(-c2ccc(C(F)(F)F)cn2)c1C +CN(C(=O)Cn1cnc2ccccc2c1=O)c1cccc2ncccc12 +CCc1nn2c(=O)cc(CN(C)CC(C)C#N)nc2s1 +COc1ccc2c(CO)cn(C(=O)OC(C)(C)C)c2c1 +COCCCn1cc(C(=O)NC2CC2)c(=O)c2c(N)cccc21 +CCCCN(CCO)C(=O)Nc1cc(Cl)ccc1OC +Nc1oc2ccc(F)cc2c1C(=O)c1cccc(F)c1 +O=C(Cn1c(C(F)(F)F)nc2ccccc21)Nc1nccs1 +Cc1cc(N)cc2c(CC(=O)NCCC(C)C)noc12 +CCCN(CC(=O)NC)c1ncnc2ccc(Br)cc12 +NS(=O)(=O)NC1CCCc2c1cnn2Cc1ccccc1 +COc1ccc(-c2cc(CO)c(C3CC3)o2)cc1C +CC(C)CC1NCCc2ccc(O)c(Br)c21 +COc1ccc(C(O)c2ccc(Br)cc2)cc1OC +Cc1nc(NCC(c2cccnc2)N2CCOCC2)cc(C(C)C)n1 +O=C(NC1CCc2c(F)cccc21)N1CCC(N2CCNC2=O)CC1 +O=C(COC(=O)c1ccsc1)c1ccc2c(c1)OCO2 +O=S(=O)(CCCc1nc2ccccc2o1)c1ccc(F)cc1 +COc1cccc(OCc2ccc(C(=O)Nc3ccon3)o2)c1 +CC(C)CCn1c(SCC(C)C)nc2c1c(=O)[nH]c(=O)n2C +CCN(CC(=O)OC)Cc1ccc(C#N)cc1F +O=C(Nc1ccc2c(c1)OCCO2)c1nn2ccccc2c1Cl +O=C(NCCc1nc2ccccc2[nH]1)c1ccc(-n2cccn2)cc1 +Cc1nc(-c2cccc(CNC(=O)Nc3nnc4ccccn34)c2)n[nH]1 +CC(C)C(C)NC(=O)NCC1(c2cccc(F)c2)CCOCC1 +CCS(=O)(=O)N1CCC(NC(=O)c2csc(C)n2)CC1 +CCCc1nnc(SCc2cc(=O)c3cc(C)cc(C)c3[nH]2)n1C +CCOC(=O)C1CCN(C(=O)Cn2nnc(-c3ccccc3)n2)CC1 +Cc1cc(F)ccc1CCNC(=O)Cn1cc(S(N)(=O)=O)cn1 +CCOC(=O)c1ccccc1NS(=O)(=O)c1cccs1 +CC1CC1NC(=O)NCCCNC(=O)C1CCC1 +CC(=O)NCc1ccc(S(=O)(=O)NC2CC2)cc1 +O=S(=O)(NCC1(c2ccc(F)cc2)CC1)c1cccnc1 +CSc1ncc(Cl)c(C(=O)NCc2ccccc2)n1 +COCCNC(=O)Cc1cc(-c2ccc(F)cc2)on1 +COc1ccccc1NC(=O)CCS(=O)(=O)c1ccc(C)cc1 +CC(C)CC(=O)Nc1ccc(Oc2ccc(S(N)(=O)=O)cc2)cc1 +O=C(Nc1cccc(Cl)c1)Nc1ccc2c(c1)C(=O)OC2 +CCCCc1cc(NC(=O)CNC(=O)c2ccc(C)c(C)c2)[nH]n1 +CC(C)(CO)N(CCO)C(=O)c1cccc(Cl)c1 +CCn1nc(-c2cc(OC)ccc2OC)cc(CC#N)c1=O +CC(C)NC(=O)Cc1csc(COc2ccccc2)n1 +CC(NC(=O)CCNC(=O)c1ccco1)c1ccc(F)c(F)c1 +CCc1cccc(C)c1NC(=O)NCC(=O)NCCOC +Cc1ccc(NC(=O)CSc2nnc(-c3ccco3)o2)cc1C +OC1(C(F)(F)F)CCN(c2cc(-c3ccccc3)nc3ncnn23)C1 +CC(Cc1ccco1)NC(=O)NCc1ncnn1C +CC(C)N1CCN(C(=O)COc2ccccc2)CC1 +Cc1n[nH]c(C)c1CCC(=O)Nc1ccccc1N1CCCC1=O +Cn1nc(NC(=O)c2ccco2)c2c1NC(=O)CC2c1ccccc1 +CC(C)(C)C(O)CCNC(=O)c1cc(C2CC2)on1 +Clc1cnn(Cc2csc(C3CCCCC3)n2)c1 +Cc1ccc(C(=O)NCCc2ccc(C(F)(F)F)cn2)c(=O)[nH]1 +CCn1cnnc1CNC(=O)NC(C)(C)c1ccc(F)cc1 +CCOC(=O)c1cccc2ncn(Cc3nccn3C)c12 +Cc1nn(CC(=O)NC(C)C2=CCCCC2)c(=O)c2ccccc12 +CCc1nccn1CCCNC(=O)c1ccccc1 +CN(C)C(=O)C1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1 +COC(=O)Nc1cccc(NCc2csc(C3CCCC3)n2)c1 +CCCC1CN(C(=O)C(C)Oc2ccc(C#N)cc2)CCO1 +CSc1nnc(Cc2ccc(Cl)cc2)c(=O)n1N +Cc1cc(CN2CCN(C(=O)Nc3ccc(C(C)C)cc3)CC2)on1 +CCOC(=O)c1sc(NC(=O)Nc2ccccc2)nc1C +O=C(NCCc1nc[nH]n1)c1cc(Cl)c2ccccc2c1O +O=C1CCc2cc(OC(=O)C3CC(=O)Nc4ccccc43)ccc2N1 +COc1ccc(F)c(NC(=O)c2ccc(SC)nc2)c1 +COc1c(F)cc(NC(=O)CCC2CCCO2)cc1F +Nc1nc(N2CCCCC2)ncc1C(=O)NC1CC1 +Cc1ccc(NC(=O)NCc2ccc(C(=O)NCC(N)=O)cc2)cc1 +CCCCOc1cccc(CNC(=O)c2cnccn2)c1 +CCCC1CN(C(=O)c2ccc(C(C)C)nc2)CCO1 +CCC(CO)NC(=O)CCc1ccc(OC)c(N)c1 +O=C(Nc1ccccc1C(=O)NCC1CCCO1)c1cccs1 +Cc1ccc2c(CC(=O)NCc3ccoc3)coc2c1 +CN1CC(C(=O)Nc2ccccc2OCCc2ccccc2)CC1=O +COc1ccc(-c2nc(NC3CC3)c(C#N)cc2C)cc1 +Cc1ccc(OCC(=O)Nc2c(C)cc(C)cc2N)cc1 +O=C(CCSc1ccccc1)NCC1(O)CCc2ccccc21 +CS(=O)(=O)N1CCCC1C(=O)Nc1ccc2c(c1)OCO2 +Cn1ncc2c(=O)n(Cc3csc4ccccc34)cnc21 +CCC(C)NC(=O)c1ccccc1S(=O)(=O)N1CCCCC1 +N#CC1CC(=O)N(c2ccccc2Oc2ccccc2)C1 +CN(Cc1cccc(C#N)c1)C(=O)NCCNC(=O)C1CC1 +COc1cc(NCC2CCCO2)nc(C(C)C)n1 +O=C1CCCN1c1ccccc1NC1CCOCC1 +O=C(NC1CCCC1)c1csc(Nc2ncccn2)n1 +CC(=O)N1CCCN(C(=O)c2csc3c2CCCC3)CC1 +Cc1ccccc1NC(=O)Cn1c(C2CC2)nc2ccccc21 +Cc1cc2c(cc1C(=O)N1CCC(O)(CO)CC1)OCCO2 +Cc1ccc(Cl)cc1N1CC(C(=O)OC(C)C)CC1=O +CN(CCc1ccccn1)C(=O)Nc1ccnc(Oc2ccccc2)c1 +Cn1nc(C(=O)N2CCn3cccc3C2c2ccccc2)ccc1=O +CN(CC(=O)N1CCCN(c2cccnn2)CC1)c1cnccn1 +C#Cc1cccc(NC(=O)CNC(=O)c2csc3c2CCCC3)c1 +CS(=O)(=O)N1CCN(C(=O)CNC(=O)c2cnccn2)CC1 +Cc1n[nH]cc1CNC(=O)CC(C)CC(C)(C)C +Cn1cccc1C(=O)Nc1ccc2c(c1)OCCO2 +COc1ccc2c(c1C)C(c1ccncc1C)NCC2 +CSc1nc2nccc(-c3ccc(C)cc3)n2n1 +CNc1sc(C(=O)c2ccc(Cl)cc2)c(N)c1C(N)=O +Cc1ccccc1N1CCN(C(=O)Cc2ccc(F)cc2)CC1=O +Cc1cccc(NCC(=O)Nc2ccc(F)c(Cl)c2)c1C(N)=O +NC(=O)c1n[nH]c2ccc(NC(=O)c3ccccc3OC(F)F)cc12 +Cc1nn(CC(=O)NCc2cscn2)c(C)c1Cl +CCN(CCCCO)C(=O)Nc1cc(F)cc(C(F)(F)F)c1 +CS(=O)(=O)N1CCC(NC(=O)c2c(F)cccc2F)CC1 +CCCC(C#N)NS(=O)(=O)c1ccc(CC)s1 +Cc1cc(C)nc(NC(=O)c2cc3c([nH]c2=O)CC(C)(C)CC3=O)n1 +Cc1cccc(C(N)=O)c1NCC(=O)NC(c1ccccc1)C1CC1 +CNC(=O)CSc1nnc(-c2ccc(C(C)(C)C)cc2)n1C +CCC(=O)c1ccc(OC(=O)CN2C(=O)COc3ccccc32)cc1 +Cc1ccc(CNC(=O)CCn2cnc3sccc3c2=O)cc1F +CCCn1c(=O)n(Cc2cc(C)c(C(=O)OC)o2)c2ccccc21 +C=CCNC(=O)NC(c1ccccc1)c1ccco1 +CC(=O)Nc1nnc(SCc2cccc(C(F)(F)F)c2)s1 +Cc1c[nH]c(=O)n1-c1ccccc1NC(=O)c1ccsc1 +Nc1c(NCCc2cccs2)ncnc1NCc1cccnc1 +CNS(=O)(=O)c1ccc(NC(=O)C(C)(C)C)cc1 +CC(=O)NCCCSc1nc2ccc(Cl)cc2[nH]1 +CCCn1c(N2CCCCCC2)nc2c1c(=O)[nH]c(=O)n2C +OC1=Nc2n[nH]cc2C(c2cccc(C(F)(F)F)c2)C1 +Cc1cc(C)n(C2CCCN(C(=O)c3csc(C4CC4)n3)C2)n1 +CC(C)(CNC(=O)NCc1ccc(OC2CCCC2)nc1)C(N)=O +COCC(=O)N1CCCC(CCC(=O)NCc2ccccc2F)C1 +COC1CCC2OCCN(Cc3cn(C)nc3-c3cccs3)C2C1 +CC(C)(C)n1ncc2c1NC(=O)CC2c1cc(F)ccc1F +Cc1cc(C)c(OCC(=O)NCCCn2ccnc2)c(C)c1 +CC(C)(C)N1CCN(C(=O)c2n[nH]c(N)n2)CC1 +CC(C)(C)OC(=O)NCCS(=O)(=O)c1ccc(N)cc1 +COc1ncc(NC(=O)c2ccccc2C(F)(F)F)c(N(C)C)n1 +NS(=O)(=O)c1ccc(NS(=O)(=O)c2cc(F)ccc2F)cc1 +CN(C)C(=O)c1cccc(NCC(=O)Nc2cccc(Cl)c2)c1 +CC(=O)Nc1ccc(C(=O)OCCOc2cc(C)ccc2C)s1 +COCCn1nc(C(=O)NC2CCC(C)CC2)ccc1=O +CCc1onc(C)c1NC(=O)NCCc1ccccc1OC +Cn1c(=O)c2nc3ccc(N)cc3nc2n(C)c1=O +C#CCN1CCN(CCOc2ccccc2C(F)(F)F)CC1 +O=C(CCCOc1ccccc1F)Nc1ccc2[nH]c(=O)[nH]c2c1 +CCCC1CN(C(=O)CNC(=O)c2cccc(Cl)c2)CCO1 +COc1ccc(C)cc1COC(=O)c1ccc(CNC(C)=O)cc1 +Cc1nn(CC(=O)NCCCc2ccccc2)c(=O)c2cccn12 +COc1c(Cl)cc(NC(=O)NCC(=O)N(C)C)cc1Cl +N#Cc1cccc(CNc2nc3cc(Cl)ccc3[nH]2)c1 +CC1CCN(c2nnc(SC(C)C(N)=O)n2C2CC2)CC1 +CN(C)S(=O)(=O)N1CCC(c2nnc(-c3ccco3)o2)CC1 +COc1ccc(N(S(C)(=O)=O)S(C)(=O)=O)cc1 +Clc1ccc(Br)cc1NCc1noc(C2CC2)n1 +O=C(NCCO)c1cc(Cl)ccc1Br +O=C(NCCCn1cccn1)C1(c2ccc(Br)cc2)CC1 +C=CCN1C(=O)C(c2ccccc2)Oc2ccc(N)nc21 +Cc1ncsc1CCOC(=O)C1CC1(Cl)Cl +COCCOc1cccc(NC(=O)c2ccccc2-n2cnnn2)c1 +Nc1ccc(OCC2CCOC2)cc1C(F)(F)F +CCOC(=O)c1sc2nc(C)nc(Oc3cccnc3)c2c1C +COc1ccc(OCCN(C)c2ncnc3sccc23)cc1 +CCOc1c(OC)cc(CN2CCOC(C#N)C2)cc1OC +OCc1nnn(Cc2cccc(Cl)c2)c1C(F)(F)F +O=C(CNC1CC1)OCc1ccc2c(c1)CCCS2 +CCCCN(C)C(=O)Nc1cc(F)c(OC)cc1OC +CN(CCc1ccccn1)S(=O)(=O)c1ccccc1F +Cc1cc(C(=O)CCC(=O)NCC2CC2C)c(C)s1 +Cc1ccc(NCc2cc3cccc(C)c3[nH]c2=O)cc1 +COC(=O)c1ncn(CCOc2c(Cl)cccc2Cl)n1 +NC(=O)COc1ccc(C(=O)OC2CCCC2)cc1 +COc1ccc(F)cc1C(=O)CCNc1c(C)cccc1C +CCOC(=O)c1nc(-c2cccc(N3CCCC3=O)c2)cs1 +Cc1c(C(=O)NC(C)C2CCCO2)oc2ccccc12 +Cn1c(C(=O)c2ccc(F)cc2)nc2c1CCCC2 +CCc1nc2n(n1)CCCC2NC(=O)C(C)Oc1ccc(OC)cc1 +CCS(=O)(=O)N1CCc2cc(C(N)=O)ccc21 +COC(=O)c1cc(CNC(=O)c2ccc(F)cc2F)ccc1OC +O=C1CCCc2[nH]c(=O)c(C(=O)Nc3cccc4c3CCCC4)cc21 +COC(=O)c1cc(NCC(=O)NC2(C#N)CCCCC2)ccc1F +COCC(=O)N1CCC2(CC(=O)N(c3cccc(F)c3)C2)C1 +O=C1CCN(C(=O)Cc2ccc3c(c2)CCC3)CCN1 +CCN1CCC2(CC1)OC(=O)C(C)=C2C(=O)N1CCCCCC1 +COCCOCCCC(=O)N1CCCc2c(F)ccc(C)c21 +COc1ccc(C(=O)N(C)c2ccccc2)cc1NC(C)=O +CCSc1cc(C(=O)NCc2ccc(Cl)cc2)ccn1 +Cc1ccc(CNC(=O)CCc2nc(-c3ccsc3)no2)n1C +Cc1nc2ccc3nc(NC(=O)Cn4cncn4)sc3c2s1 +c1cnc(NC2COC3(CCN(c4ncccn4)C3)C2)nc1 +COc1ccccc1OC(C)C(=O)Nc1noc(-c2ccccc2)n1 +COc1ccc(CC(C)CNC(=O)c2cc(C)n[nH]2)cc1 +CC(NC(=O)c1cc(S(C)(=O)=O)ccc1Cl)C1CC1 +Cc1nc(C)c(Cn2cnc3sccc3c2=O)s1 +Cc1csc(SCCC(=O)Nc2ccccc2)n1 +Fc1ccc2sc(NCC3CCOC3)nc2c1 +COCCCN(C)C(=O)NCc1ncc(C)c(OC)c1C +Cc1cc(NC(=O)COc2ccc3c(c2)CCC3)on1 +COc1ccnc(N2CCCC(c3nc4ccccc4[nH]3)C2)n1 +COCCCNC(=O)c1ccc(Oc2cccc(F)c2)o1 +CCc1nnc(CNc2cc(C)c(Cl)cc2OC)o1 +CCC(C)CC(=O)NCC1Cc2cccc(-c3cncnc3)c2O1 +Cc1noc(C)c1COc1ccc(C(=O)Nc2ccccc2F)cc1 +O=C(C1CCCO1)N1CCC(Oc2ccccc2)CC1 +CC1CN(C(=O)Cn2cc(NCC3CCOCC3)cn2)CC(C)O1 +CC1CS(=O)(=O)N(Cc2c(F)cccc2Cl)C1=O +COC(=O)c1[nH]c2ccc(C)cc2c1NC(=O)N1CCOCC1 +CCc1ncc(C(=O)N2CCN(Cc3cc(C)on3)CC2)s1 +NS(=O)(=O)c1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)cc1 +CC(C)N=c1ccccn1C(=O)c1ccc(F)cc1 +O=C(CCNC(=O)c1ccc(Oc2nccs2)cc1)NC1CC1 +CC(=O)c1cc(Br)ccc1N1CCCC1 +CN(C)S(=O)(=O)N1CCN(CCOc2cccc(F)c2)CC1 +CCNC(=O)CN1CCN(C(=O)c2ccn(CC)n2)CC1 +CCN1CC(C(=O)N(C)Cc2ccccc2OC(F)(F)F)CC1=O +O=C(c1cn(-c2ccccc2)nc1-c1cccs1)N1CCCC1 +Cc1ccc(C(=O)Oc2cccc(C(=O)NC3CC3)c2)c(C)n1 +CC1CCCCN1C(=O)c1ccc(NC(=O)c2cc[nH]n2)cc1 +COc1ccc(C(=O)N(C)Cc2ccc(C)s2)cc1OCCO +COCC(=O)N1CCOC2C(OCC3CCOCC3)CCC21 +CS(=O)(=O)c1cccc(NCc2nc(C3CC3)no2)c1 +CS(=O)(=O)NCCN1CCOc2ccc(F)cc21 +COc1ccc(-c2nnc(SCCOC(C)C)n2N)cc1 +CC(=O)c1cccc(OC(=O)COc2ccc3ccc(=O)oc3c2)c1 +O=C(CNC(=O)c1cccc2[nH]ncc12)NCC(F)(F)F +O=C(COc1ccccc1)NCCc1cnn(-c2ccccc2)c1 +CC(O)CN1CCN(C(C)C(=O)NCc2ccc(Cl)cc2)CC1 +COc1cc(C)c(NC(=O)C(CC(C)C)NC(N)=O)cc1OC +O=C(Nc1ccc2c(c1)COC2)NC1CCN(c2ncccn2)CC1 +CCn1c(C)cc(=O)c2cc(C(=O)Nc3ccc(OC)cc3)ccc21 +COc1ccc(OCC(=O)Nc2nc3c(s2)COCC3)cc1 +COc1ccc2c(CSc3n[nH]c(=O)n3C3CC3)cc(=O)oc2c1 +O=C(Cc1ccccc1)Nc1ccc(-c2cn3cccnc3n2)cc1 +CCOC(=O)N1CCC(NS(=O)(=O)c2c(C)noc2C)CC1 +N#Cc1ccc(OCCN2CCOC(Cn3cncn3)C2)cc1 +CCOC(=O)CNC(=O)c1sc2cccc(F)c2c1Cl +O=C(NCC1CC1)C1CCN(C(=O)N2CCCC2)CC1 +CSc1ccc(-n2ncnc2C(C)OC(C)C)cc1 +CC1CCCC(CNC(=O)Nc2ccc(F)c(C(N)=O)c2)C1 +CCOC(=O)C(C)NC(=O)Cn1cc(N)ccc1=O +c1ccc(OCC2(CNc3nccc(-c4ccccn4)n3)CC2)cc1 +CCc1noc(C)c1NC(=O)Nc1cccc(Oc2ccncc2)c1 +CC(C)(C)OC(=O)N1CCCC(Oc2ccncc2)C1 +NC(C(=O)NCc1ccc[nH]1)c1cccc2cc[nH]c12 +C=CCN1CCN(C(=O)CCc2ccccc2)CC1 +CC(COc1ccc(F)cc1F)NC(=O)C1CCCN(C(N)=O)C1 +Cc1noc(C)c1CNC(=O)NCCc1c[nH]c2cc(F)ccc12 +O=C(NCCS(=O)(=O)c1ccccc1)Nc1nncs1 +CCOC(=O)C(NC)c1nc(-c2ccccn2)cs1 +CCCNC(=O)c1ccc(Cl)cc1NC(=O)Cn1cnnn1 +CCCCNC(=O)Nc1c(C)c(C)nn1CCO +Cc1cc(C)cc(C2(C(=O)N3CCCn4ncnc43)CC2)c1 +CC1C(=O)OC(c2ccccc2)N1C(=O)OCc1ccccc1 +COc1cccc(CNC(=O)c2ccc(Br)cc2)c1 +O=C(NCc1cn(-c2ccccc2)nn1)c1ccc2ccccc2n1 +OC(CNc1ccc(-c2ccccc2)nn1)c1cccnc1 +COCc1cccc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)c1 +COC(=O)c1cc(CNC(=O)N(C)Cc2ccoc2C)oc1C +COC(=O)c1sccc1NC(=O)Nc1ccc(OC)cc1OC +O=c1cc(CSc2ccc(F)cc2)nc2ccccn12 +COc1ccc(Cl)c(NC(=O)CCc2ccccn2)c1 +C=CCC(=O)N1CCc2[nH]nc(-c3ccc4c(c3)OCO4)c2C1 +COc1cc(CNc2ncnc3[nH]cnc23)c2ccccc2n1 +Cc1noc(-c2ccccc2OCC(=O)Nc2ccc(C)c(C)c2)n1 +Cc1ccc(-c2ncco2)cc1NC(=O)CCC1CC1 +COC(=O)Nc1ccc(NCc2cnc3ccc(C)cn23)cc1F +N#CC(Cc1cccc2[nH]ccc12)C(=O)Nc1ccc(O)cc1 +CCCCn1nc(C(=O)NCc2ccccc2Cl)ccc1=O +CCN(CC(C)C#N)S(=O)(=O)c1ccc(Cl)c(C#N)c1 +CCCc1nnc(SCC(=O)Nc2ccccc2CC)n1N +CC(C)NC(=O)C1CCN(c2cccc(Cl)c2)CC1 +COCC(C)(C#N)NC(=O)c1cccc(OCC(F)F)n1 +CN(C)c1ccc(NC(=O)CNC(=O)NCc2ccc(F)cc2)cn1 +CC(N1CCOC1=O)S(=O)(=O)c1ccccc1 +CNc1sc(C(=O)c2ccc(F)cc2)c(N)c1C#N +CCN(Cc1nc(COC)no1)C(=O)c1ccc2cc[nH]c2c1 +O=C1COc2cc(NC(=O)c3ccc4c(c3)CCC4)ccc2N1 +O=S(=O)(c1ccccc1)N1CCOC(CCc2ccccc2)C1 +Cc1ccc(C(=O)Nc2ccccc2CC(N)=O)cc1F +CC(=O)c1ccc(-c2cncc(C(=O)NCc3ccco3)c2)cc1 +C=CCOc1ccc(CN(C)C(=O)c2cncc(C)c2)cc1 +CCC(C)NC(=O)c1nc(-c2ccccc2)n(-c2ccccc2)n1 +Cc1nc(C)n(CC2CN(Cc3cccc(C(N)=O)c3)CCO2)n1 +CCOC(=O)N1CCCC(C(=O)NC2CCCCC2)C1 +Cc1noc(CCCC(=O)N2CCCC(n3nc(C)nc3C)C2)n1 +Cc1ccc(=O)n(Cc2nc(CC(=O)Nc3ccccc3)no2)n1 +COc1ccccc1C(C#N)NC(=O)c1cccc(F)c1 +COC(=O)c1cc(OC)cc(OC)c1S(N)(=O)=O +Cc1cc(NC(=O)NC2CCN(S(C)(=O)=O)CC2)no1 +Cc1ccc(S(=O)(=O)N(CCO)C2CC2)c(Br)c1 +Cc1cc2nc(SCC(=O)NCc3ccco3)[nH]c(=O)c2[nH]1 +COC(=O)CCCC(=O)c1ccc(Cl)c(Cl)c1 +COCC1c2nnn(CC3CC3)c2CCN1C(=O)c1cscn1 +CSc1ccc(S(=O)(=O)N2CCCC(C)(C)C2)cc1 +CN(CCOc1ccccc1)c1ccc2nnc(C(F)(F)F)n2n1 +O=C(COc1ccc(F)cc1)N1CCC(Cn2cccn2)CC1 +Nc1cc(N)nc(SCc2nc(-c3cccs3)no2)n1 +Cc1nc(S(=O)(=O)N2CCN(C3CCCCC3O)CC2)cn1C +O=C1CN(C(=O)CCc2cc(F)ccc2F)CCN1 +O=C(NCC1(O)CCCCCC1)Nc1ccccc1F 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+Cc1nc(N)ccc1NC(=O)COc1ccccc1 +CC(C)C(C)NC(=O)CN1CCc2cc(S(N)(=O)=O)ccc21 +CN(Cc1cnn(C)c1)C(=O)Nc1cccc(N2CCCCC2)c1 +Cc1ccccc1OCC(=O)N1CCN(CC(F)F)CC1 +NS(=O)(=O)CCNC(=O)C1CC1c1ccc(Br)cc1 +Cc1cnc(C(=O)Nc2cccc(C=Cc3ccccn3)c2)cn1 +O=C(CSc1nccc(=O)[nH]1)Nc1ccc(F)cc1F +CC1CN(C(C)CNC(=O)NCCNc2cnccn2)CC(C)O1 +COCCNC(=O)CSc1nnc(-c2ccco2)n1C +CC(C)c1nc(CN(C)Cc2ccc3cccc(Cl)c3n2)no1 +Cc1cccc(CN2CCN(C(=O)Nc3cnccc3C)CC2)c1 +COC(=O)c1ccc(C(=O)Nc2nnc(C3=COCCO3)o2)cc1 +CCOc1ccc(C(=O)OCCn2nc3ccccn3c2=O)cc1 +CCC(C(=O)NCc1ncc[nH]1)n1cc(C(C)=O)c2ccccc21 +Cn1cc(C2CC(=O)NC23CCN(C(=O)c2ccnnc2)CC3)cn1 +Cc1ccc(OCc2nnc(NC(=O)c3ccco3)s2)c(C)c1 +COc1cccc(CNc2cccc(SC)c2)c1OC +O=C(Nc1ccc2c(c1)OCCO2)c1ccc(-n2cccn2)cc1 +COc1cccc(S(=O)(=O)NCC2(O)CCc3ccccc32)c1 +CCOC(=O)c1cc(C)sc1NC(=O)CN1CCOC(C)(C)C1 +CCc1cccc(C)c1NC(=O)NCCCn1cnc2ccccc21 +CC(C)c1noc(CCNC(=O)CCc2ccc(F)cc2)n1 +CCC1COCCN1Cc1ccc(F)c(C(F)(F)F)c1 +CC1CCc2ccccc2N1C(=O)Cn1cnc(C#N)n1 +COCCCN(C)C(=O)Nc1ccc(Oc2ncccn2)cc1 +COc1ccc(CNC(=O)c2cc(C)ccc2C)c(OC)c1 +CCc1nc(CC(=O)NC(C)C(C)CC)cs1 +CN(CCC#N)C(=O)Cn1c(N)nc2cc(Cl)ccc21 +COCCNC(=O)CNC(=O)Nc1ccnn1C1CCCCC1 +CCC(C)n1ncc(C(=O)NCc2cc(F)ccc2F)c1C1CC1 +Cc1nc(CC(=O)Nc2ccccc2C(=O)C(C)C)cs1 +Cc1csc(S(=O)(=O)CCCOc2ccc(F)cc2)n1 +CC1(C)C(NC(=O)c2ccccc2S(C)(=O)=O)C2CCOC21 +Cc1cc(Cl)c2oc(C(=O)N3CCC(C(N)=O)CC3)c(C)c2c1 +COC(=O)C(C)NC(=O)CSc1ccc(F)cc1 +Cc1cccc(N2CCN(c3nc(=O)[nH]nc3C)CC2)c1 +Cc1cc(F)ccc1NC(=O)c1cc(Cl)ccc1N +CC1=CC(C)=NC1C(=O)N1CCCC(C(=O)NC2CCCCC2)C1 +CCCCc1nc(-c2nccn2Cc2noc(-c3ccco3)n2)c[nH]1 +Cc1nc(C(N)=O)c2c(n1)n(-c1ccc(C)c(C)c1)c(=O)n2C +Cn1cccc1C(=O)C(C#N)c1nc(-c2ccc(Cl)cc2)cs1 +CC(=O)Nc1ccc(C2NCCc3c(N)cc(F)cc32)cc1 +O=C(COc1ncnc2ccccc12)Nc1c[nH]c2ccccc12 +CC(C)Cc1cc(C(=O)NC(Cn2cccn2)c2ccccc2)on1 +CC(c1cccnc1)N(C)C(=O)CCc1nnc(-c2ccsc2)o1 +O=C(NCc1ccc2c(c1)OCO2)N1CCc2ccc(O)cc2C1 +CNC(=O)c1ccsc1NC(=O)COc1ccc(C(C)C)cc1 +CC(=O)c1csc(NC(=O)COc2ccccc2C#N)n1 +Cc1nc(C)c(C(=O)Nc2nc3ccccc3s2)s1 +COc1ccc(NC(=O)N2CCC(OCC(C)C)CC2)cn1 +Cc1nc(CC(=O)N2CCCCC2c2cccc(F)c2)cs1 +Cc1ccc(Nc2nn[nH]c2C(=O)NCc2ccc(F)cc2)cc1 +CCN(CCO)S(=O)(=O)c1cccc(S(N)(=O)=O)c1 +O=C(NCc1nccs1)c1sccc1OC(F)F +COc1cc(C#N)ccc1OC(C)C(=O)NC(C)c1ccc(F)cc1 +CCOc1ccccc1OCc1csc(CC)n1 +COC(=O)C1CCN(C(=O)CN2c3ccccc3CCC2C)CC1 +COCCN(Cc1cccs1)C(=O)c1cc(F)cc2[nH]cnc12 +CC(C)CNC(=O)N1CCN(S(C)(=O)=O)CC1 +C=CCCOC(C)C(=O)N1CCn2c(nnc2C(C)C)C1 +CC(=O)Nc1ccc(C(=O)COC(=O)c2ccc(C#N)cc2)c(F)c1 +CCCCN(CCO)C(=O)Nc1ccc(NC(C)=O)cc1 +O=C(COC(=O)C1(c2ccc(F)cc2)CC1)NC1CCCCC1 +CCC(CC)NC(=O)C1CCN(C(=O)c2cccc(F)c2)CC1 +O=C(Nc1nc2ccccc2s1)c1ccc(-n2ccnc2)nc1 +O=C(CCSc1ccc2c(c1)OCCO2)N(CC(F)F)C1CC1 +COCCNC(=O)COc1ncnc2sccc12 +COC(=O)c1cc(CN2CCOCC2C2CC2)c[nH]1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCCn1cccn1 +O=C(c1ccccc1-n1cnnn1)N1CCC2(CCCCC2)C1 +CN(Cc1nc2ccccc2[nH]1)C(=O)c1c[nH]nc1-c1ccc(F)cc1 +O=C(NC1CCc2c(Cl)cccc21)N1CCC2(CC1)OCCO2 +Cc1nn(C)c(C)c1CN1CCN(C(=O)C2CCCO2)CC1 +CC(=O)Nc1ccc(NC(=O)Nc2c(C)cccc2C)cc1 +CCOc1cc(C)ccc1NC(=O)N1CCN(c2nccs2)CC1 +O=C(Nc1ccc(Cl)c(C(=O)NC2CC2)c1)c1cc[nH]n1 +COc1ccc(S(=O)(=O)N2CC(NC(=O)c3ccoc3)C2)cc1 +COC(=O)C1(NCc2csc(NC(C)=O)n2)CCCC1 +Cc1csc(CNc2ccccc2Oc2ncccc2C#N)n1 +CC(C)CCC(=O)N1CCN(C(=O)NCC(=O)N2CCCC2)CC1 +Cc1ncc(CN(C)C(C)c2ccc(S(N)(=O)=O)cc2)s1 +CCOc1cc(NC(C)(C)C)nc(C2CCCO2)n1 +CCOC(=O)N1CCC(OC(=O)c2sc(C)nc2C)CC1 +O=C(C1CCC1)N1CCC(c2ncc(-c3ccc(F)c(F)c3)[nH]2)CC1 +COC(=O)c1ccc(-c2ccc(C(=O)N(C)C)cc2OC)cc1 +NC(=O)c1ccc(S(=O)(=O)N2CC=C(c3ccccc3)CC2)cc1 +N#Cc1cccc(S(=O)(=O)N2CCc3sccc3C2)c1 +CCc1ccc(C(=O)N2CCC(n3cnc4ccccc43)CC2)cc1 +Cc1cc2c(=O)n(C3CCN(C)C3=O)cnc2s1 +CCOc1cc(C#N)ccc1OCC(=O)NCc1ccccc1 +Cc1cccc(Sc2ccncc2S(N)(=O)=O)c1 +COc1ccc(CCC(=O)N2CCN(Cc3ncc(C)o3)CC2)cc1 +CCCNC(=O)c1cccc(NC(=O)Cc2ccccc2C)c1 +O=C(NCc1ccccc1-n1cccn1)c1ccnc(-n2ccnc2)c1 +O=C(NCCNC(=O)c1ccco1)NCc1ccc(F)c(Cl)c1 +CCC(=O)c1ccc(OCC(=O)Nc2cccnc2)cc1 +Cc1cccc(OCC(=O)Nc2ncc(C)s2)c1 +Cc1ccc(NC(=O)NCc2noc3ccc(C)cc23)nc1 +O=C1CC(C(=O)Nc2cc(Cl)ccc2Cl)c2ccccc2N1 +Cc1cc(CN2CCN(C(=O)N(C)C)CC2)c2ccccc2n1 +Cc1ccc(CNC(=O)CNc2c(F)cccc2F)cc1 +O=C(Cn1ccnc1)Nc1cnn(-c2ccccc2Br)c1 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+CCN1CCCC2(CCN(C(=O)Cn3nc(C)ccc3=O)C2)C1=O +COC(=O)CN(Cc1cc(C(N)=O)cs1)C(C)C +CN(Cc1ccco1)C(=O)C1(C)Sc2ccccc2NC1=O +CC1(C)CN(C(=O)c2ccc(NC(=O)c3ccco3)cc2)CCO1 +CC(NC(=O)Nc1ccc(Cl)c(F)c1)c1nnc2ccccn12 +Cc1cc(CNC(=O)NCc2ccc3c(c2)OCO3)on1 +Cc1nc(C)c(C(=O)Nc2ccc(S(C)(=O)=O)cc2)s1 +CC1CCCCC1NC(=O)c1cccc(N(C)C)c1 +Cc1nc(CNC(=O)Nc2ccn(C)n2)c(C)s1 +CNC(=O)C(C)Sc1n[nH]c(C=Cc2ccc(C)o2)n1 +CCC(C)C(=O)OCc1cc2ccccc2[nH]c1=O +CCC(=O)N1CCN(c2ccc(F)c(Cl)c2)C(=O)C1C +Cc1ccc(F)cc1C(=O)Nc1ccc(CC#N)cc1 +Cc1ccccc1-c1nnc(SCC#CCO)o1 +Cc1nnc(CC2CC3CN(C(=O)Cc4ccccc4)CC3O2)o1 +Nc1cc(C(=O)NCC2CCCC2)c(Br)cc1F +N#Cc1ccc(NC(=O)c2ccc(Br)cc2)cc1 +Cc1nc(CCc2ccc(OC(C)C)cc2)nc(C)c1N +CC(C)c1noc(CCC(=O)Nc2ccc(-c3ccccc3)nn2)n1 +Cc1occc1C(=O)NC1CCN(c2c(F)cccc2F)C1 +Cc1cc(C(=O)NCc2cn[nH]n2)c(C)n1C1CCCCC1 +COc1ccc(NC(=O)Cc2nc(-c3ccccc3)n[nH]2)cc1OC +COC(=O)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 +COc1ccc(C(O)CNc2ccccc2C)cc1F +CCCn1cnnc1COC(=O)c1ccc(-n2ccnc2)cc1 +Cn1cc(C2NCCc3cc(Cl)cc(F)c32)cn1 +Cc1cc(=O)oc2c3c(ccc12)OC(=O)CC3c1ccccc1 +CCC(C)(C)NC(=O)CSc1nnnn1-c1ccc(Cl)cc1 +CC(=O)Nc1ccc(Sc2ccc(C(=O)NC3CC3)cn2)cc1 +Cc1ccccc1C(=O)NC(C(=O)NC(C1CC1)C1CC1)C(C)C +CC(NC(=O)c1cc(-c2cnn(C)c2)[nH]n1)c1ccc2c(c1)CCC2 +O=C(NCCc1ccccc1F)Nn1cnc2ccccc21 +O=C(c1cc(-c2csc(NC3CCCCC3)n2)c[nH]1)N1CCCC1 +CC(=O)c1cccc(NC(=O)C2CCCN(CC(F)(F)F)C2)c1 +CCOc1ccc(-c2cc(C(=O)OC)n(CCO)n2)cc1 +CCOc1cccc(NC(=O)c2ccc(C(=O)OC)cc2)c1 +CCS(=O)(=O)NCc1ccc(C(C)(C)C)cc1 +CCC(=O)NC(C)c1nc2ccccc2n1CC(=O)N1CCOCC1 +O=C(CCC(=O)c1ccc(F)cc1)Nc1cccc(-c2cn[nH]c2)c1 +COc1ccccc1-c1ccc(C(C)=O)c(=O)n1C1CC1 +Cn1cc(-c2cccc(CNc3ncnc4oncc34)c2)cn1 +CN(C)C(=O)c1ccnc(NC(=O)c2scnc2C2CC2)c1 +Cc1ccc2ncc(C(=O)Nc3ccc(F)nc3)n2c1 +Cc1ncncc1C(=O)N1CCNC(c2ccccc2)C1 +CCCCNC(=O)NCCNC(=O)c1ccc(C)c(F)c1 +Cn1ccnc1SCc1noc(-c2ccc(F)cc2)n1 +Cc1cc(C)cc(NCc2nc(C(F)(F)F)cc(=O)[nH]2)c1 +Cn1cnnc1S(=O)(=O)Cc1ccc(Cl)c(Cl)c1 +CCOc1cc(F)ccc1NC(=O)c1ccc(OC)cc1 +N#Cc1cccc(NC2CC(=O)N(Cc3cccc(F)c3)C2)n1 +Cc1ccc(CC(=O)N2CCC(OCc3ccc(F)cc3)CC2)cn1 +CC(C)CN(CC(C)C)C(=O)CCN1C(=O)COc2ccccc21 +Nc1cc(-c2nnc(N3CCOCC3)o2)ccc1Cl +CCn1ccc(NC(=O)c2nnsc2-c2ccccc2)n1 +Cn1cc(CNc2cccc(OC(F)(F)F)c2)c(-c2ccncc2)n1 +Nc1ccccc1CCc1nnc(N2CCOCC2)s1 +CCOc1cc(C(=O)N2CCOCC2CC(C)C)ccc1C +CCOc1ccc(C(=O)Nc2ccc(CNC(N)=O)cc2)cc1 +Cc1nn2cccnc2c1C(=O)OCc1cc(Cl)c2c(c1)OCO2 +Cc1c(Br)c(C)c2oc(=O)[nH]c2c1C +C#CCOc1ccc(CCNC(=O)c2ccc(-n3cccn3)cc2)cc1 +CCn1cc(NCc2cccc(F)c2F)c(C)n1 +COc1ccccc1CNC(=O)c1cnn(-c2ccccc2)n1 +CC(C)c1noc(CCNC(=O)N(C)Cc2cc(Cl)cn2C)n1 +COCCCNC(=O)Cn1c(C)c(C)sc1=O +COc1ccccc1C1CCN(C(=O)C2CCC2)CC1 +CCCCNC(=O)C(C)Sc1nnnn1-c1ccc(Cl)cc1 +COc1ccc(-c2noc(COC(=O)c3c(C)noc3C)n2)cc1 +O=C1CN(C(=O)CCOc2ccc(Cl)cc2)c2ccccc2N1 +NC(=O)c1ccc(C(=O)N2CCc3cc(F)ccc3C2)nc1 +CCN(C)c1ccc(-c2nc(-c3ccnc(OC)c3)no2)cc1 +O=C(NCCCn1cccn1)c1ccc(Br)cc1F +CCOc1cc(Cc2n[nH]c(=O)c3ccccc23)ccc1O +OC(c1ccc2c(c1)OCO2)C(O)c1ccc2c(c1)OCO2 +CCOc1ccc(CNC(=O)c2cn3cc(Cl)ccc3n2)cc1 +Cc1cc(NC(=O)COc2ccc(Cl)cc2C)no1 +CCc1cccc(NC(=O)CNC(=O)C2CC3CCC2O3)c1 +CC(=O)N1c2ccccc2CC1C(=O)NCc1ccco1 +O=C(c1cccc(OCC(F)F)n1)N1CCC(Cc2ccccc2)C1 +NC(=O)Cc1ccc(NC(=O)c2csc3ccccc23)cc1 +O=C(CCCc1ccccn1)NC1COc2ccccc2C1=O +CC(Cn1cncn1)Nc1nc(-c2ccccc2)ns1 +CCCNc1ccc(C#N)cc1NC(=O)c1scnc1C1CC1 +Cc1ccoc1C(=O)N1CCCN(C(=O)c2ccncc2)CC1 +CN(C)C(=O)c1ccc(Cn2c(-c3ccccn3)noc2=O)cc1 +O=C(Cc1ccc2c(c1)OCCO2)NC1CCCCNC1=O +NC(=O)C1CCCN(C(=O)CCc2nc(Cc3ccccc3)no2)C1 +COc1ccc(NC(=O)c2ccc(C#N)cc2)cn1 +COC(C)c1nc(C)c(C(=O)Nc2n[nH]c(C(C)C)n2)s1 +C=CCNS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +COc1ccc(CNC(=O)NCCc2ccccc2)c(OC)c1 +Cn1nc(C(=O)NCc2ccccc2)cc1-c1cccc(F)c1 +CC1Oc2c(cccc2C(=O)Nc2cccc(C(F)F)c2)NC1=O +COc1ccc(C(CNCc2cccc(F)c2)N2CCOCC2)cc1 +CC(C1CC1)N(C)C(=O)c1ccc(OCc2ccccc2C#N)cc1 +Cc1ccc(-c2ccc(=O)n(C(C)C(=O)NCc3ccccn3)n2)cc1 +CCOC(=O)c1cccc2cnn(C(C)C(=O)OC)c12 +Cc1ccc2[nH]c3c(N4CCCCC4)ncnc3c2c1 +CC(C)CNC(=O)c1cn(C)nc1-c1ccncc1 +COCc1nc(NCc2ccncc2)cc(OC)n1 +CCn1cc(C(=O)N(CC2CC2)C2CCCCC2)cn1 +N#Cc1ccccc1COc1ccc2c(c1)OCO2 +CCC(C)n1ncc(C(=O)Nc2ccc(C(N)=O)cc2)c1C1CC1 +Nc1ccc(Cl)c(-c2nnc(N3CCCC3)o2)c1 +CCOC(=O)c1csc(NC(=O)c2cn(C)nc2C(F)(F)F)n1 +CC(Sc1ccccn1)C(=O)N1CCN(c2ncccn2)CC1 +Cc1n[nH]c(C)c1CNC(=O)c1cc(COc2cccc(F)c2)[nH]n1 +Cc1cc(N)c2onc(CC(=O)Nc3cccc(F)c3)c2c1 +O=C(OCCc1nc2ccccc2s1)C1CCC1 +Cc1noc(C(C)C)c1C(=O)N=c1sccn1C +COCCCNC(=O)C1CC(=O)N(C2CCCC2)C1 +CCN(Cc1ccco1)C(=O)CN1C(=O)CSc2ccccc21 +O=C(Cc1ccc(F)cc1)Nc1nnc(C(F)(F)F)s1 +CN(Cc1cccc(C#N)c1)C(=O)Cn1cccc(C(F)(F)F)c1=O +O=C(Nc1nnc(-c2ccco2)s1)c1cccc(Cl)c1 +CN(C)S(=O)(=O)N1CCCN(C(=O)c2ccccc2Cl)CC1 +Cc1ccc(F)c(S(=O)(=O)NC(C)(C)CO)c1 +CCOc1cc(Br)ccc1OCC#N +CCc1ccccc1NC(=O)CCC(=O)N1CCCn2nc(C)cc21 +CCc1oc2ccccc2c1CN(C)C(=O)CCOC(C)C +CCn1cc(NC(=O)c2ccc(F)cc2Br)cn1 +CCc1cc(O)n2nc(C3CCCCN3C(=O)C3CCOC3)cc2n1 +CCN(C1CC1)S(=O)(=O)c1cc(Br)cnc1N +Cc1nc2ccccc2nc1NCc1cnn(C)c1 +c1ccc(-n2ncc(CN3CCOC(C4CCCO4)C3)n2)cc1 +O=C(NCc1cnn2ccccc12)c1cnn(-c2ccccc2)n1 +COC(=O)CN(Cc1ccccc1Cl)C(=O)Cn1cnnn1 +CC(=O)Nc1ccc(-c2nccn2Cc2cccc(C#N)c2)cc1 +CNS(=O)(=O)c1ccc2c(c1)NC(=O)C(C)(C)O2 +COCC(=O)Nc1ccc(NC(=O)NC(C)c2ccccc2)cc1 +CCn1cc(-c2cc(-c3cnn(C)c3)c(C#N)c(N)n2)c2ccccc21 +CC(=O)NCC(=O)Nc1cccc(NC(=O)C2CC2)c1 +c1cnc2cc(-c3nc(C4CCOC4)no3)nn2c1 +Cc1cc(C(=O)Nc2nnc(CS(=O)(=O)c3ccccc3)o2)no1 +CCn1cnnc1CNC(=O)Nc1cc(C)on1 +C#CC1OC2OC(C)(C)OC2C1OCc1ccccc1 +O=C(Nc1nc[nH]n1)C1CCCN(C(=O)c2ccc(Cl)cc2)C1 +CC(=O)N(CCc1ccccc1)CC(=O)Oc1c(C)nn(C)c1C +CC(=O)c1c(F)cccc1N1CC(C)OC(c2ccsc2)C1 +COC(=O)COC(=O)c1c(NC(=O)C2CC2)sc(C)c1C +Cc1ccccc1NC(=O)Nc1ccc(F)c(C(N)=O)c1 +O=C(COc1ccc2ccccc2c1)NCc1ccsc1 +NC(=O)Cn1nc(-c2ccc(N3CCCCC3)cc2)ccc1=O +O=C(NC1CCC2CCCC21)c1ccn(C(F)F)n1 +COc1c(F)ccc2c1C(Cc1ccc(O)cc1)NCC2 +CCc1onc(C)c1NC(=O)NC(C)(CC)CC +Cc1ccc(Cl)cc1NC(=O)c1cnn(C)c1N +CCOc1ncccc1CNS(=O)(=O)c1ccc(C(=O)NC)cc1 +Cc1ccccc1-c1ncc(C(=O)NCCC(C)C)c(N)n1 +Cn1nc(C(=O)NC(c2ccccc2)c2ccccn2)ccc1=O +COc1ccc(Cl)cc1N1C(=O)C2CC1CN2Cc1cccnc1 +Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)CC1C=CCC1 +CCNC(=O)CNC(=O)CCn1ncc2cccc(C)c21 +CCOc1nnc(CN2CCN(S(C)(=O)=O)CC2)s1 +Cc1cc(C(=O)NCCc2csc(C)n2)c(C)o1 +O=C(Nc1cc[nH]n1)c1ccc(=O)n(-c2ccc(F)cc2)n1 +Cc1cc(C)c(NC(=O)Cn2nc(C)c3ccccc3c2=O)c(C)c1 +CC1CC(C)CN(C(=O)Nc2cccc3cccnc23)C1 +Cc1ccccc1-n1nnnc1SC(C)C(=O)Nc1ncccn1 +COC(=O)C1(NC(=O)c2ccccc2Br)CCCC1 +COCCNC(=O)c1nnc(Cc2ccc(Cl)cc2)o1 +O=C(NCc1cccnc1)c1cccc2c1-c1ccccc1C2=O +Cc1noc2ncnc(N3CCN(c4cccc(Cl)c4)CC3)c12 +CC1CCc2onc(C(=O)NCCc3c[nH]c4ccccc34)c2C1 +NC(=O)C1(NC(=O)C2CCOCC2)CCCCC1 +CC(Sc1ccccn1)C(=O)N(C)CCc1ccccc1 +O=C(COC(=O)c1cccc(-n2cccc2)c1)Nc1ccccc1 +N#Cc1ccc(C(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)cc1 +CCN(CC(=O)Nc1cccc(OC)c1)c1ccnc(C)n1 +CC(=O)c1c(C)[nH]c(C(=O)CN2CCOC(c3ccccc3)C2)c1C +CC(C(=O)NC(C)(C)C)N1CCN(c2cccc(Cl)c2)CC1 +Cc1cc(C)n(C(C)c2nc(-c3cccnc3)nn2C)n1 +CSc1ccc(Cl)cc1NC(=O)NC(C(N)=O)C(C)(C)C +CC(C)NC(=O)CSc1nc2ccccc2n1C(F)F +CCN(CC)C(=O)CCC(=O)C(C#N)c1ccc(F)cn1 +Cc1cc(CNC(=O)C2(c3ccccc3)CCOCC2)c(C)o1 +NC(=O)Nc1cccc(C(=O)Nc2cccc(Cl)c2)c1 +COc1ccc(C(=O)Nn2cnc3ccccc32)cc1F +Cc1sc(NC(=O)C2COc3ccccc3O2)c(C#N)c1C +O=C(c1ccc(F)cc1Br)N1CCCC(O)C1 +Cc1ccccc1CN1C=NS(=O)(=O)c2ccccc21 +CCc1ccc2oc(C(=O)NCc3cnn(C)c3)cc(=O)c2c1 +COc1ccc2c(c1)nc(C(C)=O)n2Cc1cccnc1N +COc1c(NC(=O)C2CC23CCCc2ccccc23)c(C)nn1C +C#CCNC(=O)NC1CCCOc2ccc(F)cc21 +CCc1n[nH]c(C2CN(Cc3nc(C4CC4)no3)CCO2)n1 +CC(C)COc1ccccc1NC(=O)N(C)C(C)CC#N +C#CCNC(=O)NC(c1cc(OC)cc(OC)c1)c1nccn1C +COc1cccc(N2CCN(C(=O)Nc3ccccc3)CC2)c1 +Cn1c(CNC(=O)c2coc3ccccc23)nnc1C1CCC1 +CCc1ccc(C(=O)N2CC(=O)Nc3ccccc32)cc1 +Cc1ccc(C(=O)NCCc2ccc(O)cc2)c(C)c1 +CCOC(=O)CN(C(=O)c1c(C)noc1C(C)C)C(C)C +Cc1cc(C)c(NC(=O)c2cccc(NC(=O)c3ccco3)c2)c(C)c1 +CC(=O)N1CCCC1C(=O)NCc1ccccc1C +C=CCn1cnc2c1c(=O)n(CC)c(=O)n2-c1cccc(Cl)c1 +COc1cc(-c2noc(C(C)Sc3nnnn3C3CC3)n2)ccn1 +CC(NC(=O)NCc1ncn(C)n1)C(C)c1ccccc1 +COc1cccc(C(=O)N(C)Cc2nc(-c3cccc(C)c3)no2)c1 +Cc1ocnc1CNS(=O)(=O)c1cc(Br)ccc1F +Cc1ccc(NC(=O)Cn2nc(-c3cccs3)oc2=O)cc1 +O=C(NC1CCCC1)c1cnc2c(cnn2Cc2ccccc2)c1 +CNC(=O)c1n[nH]c2c1C(Cc1ccccc1)CC(=O)N2 +CCC1c2ccccc2CCN1C(=O)c1ccc(C)c(NC(C)=O)c1 +O=C(CNCc1ccccc1)Nc1ccc(F)cc1 +CC(C)(C)c1noc(CCC(=O)OCc2ccc(F)cc2)n1 +O=C(CCc1cccnc1)Nc1ccc(N2CCOCC2)cn1 +COCCCNC(=O)C(C)n1cc(Br)cn1 +CCNS(=O)(=O)c1cc(N)c(OC)c(OC)c1 +Cc1ccc(CN(C)C(=O)c2nn(-c3ccccc3)c(C)cc2=O)o1 +CCc1nc2n(n1)CC(C(=O)Nc1ccc(Cl)cc1)=C(C)N2 +COc1cc2nc(C(=O)NC(C)(C)C)n(C)c2cc1OC +CCS(=O)(=O)NCCOc1ccc(C(C)C)cc1 +COc1ccc2c(c1OC)C(c1nccs1)NCC2 +COc1ccccc1C(NC(=O)C1CCNC(=O)C1)c1ccccn1 +CCC(=O)N1CCCN(C(C(=O)N(CC)CC)c2ccccc2)CC1 +N#Cc1cc(N)cnc1Sc1nc2ccccc2[nH]1 +Cc1nc(CNC(=O)N2CCc3c(F)cc(F)cc3C2)oc1C +O=C(NCc1cc(Br)cs1)c1sccc1C1CC1 +CCOc1ccc(NS(=O)(=O)c2ccc3c(c2)oc(=O)n3C)cc1 +CCCC(=O)N1CCCC1C(=O)N1CCC(C)CC1C +COC1CCN(C(=O)C(C)Oc2ccc3c(c2)OCO3)CC1 +CCCn1nnnc1COc1ccc2ccc(=O)oc2c1 +O=C(NCCOc1ccccc1)NCC(O)c1ccc2c(c1)CCO2 +CC(Oc1ccccc1C#N)C(=O)Nc1nc2c(s1)CN(C)CC2 +CN(Cc1ccsc1)C(=O)NCC1Cc2ccccc2O1 +O=C(CSc1ccc(F)c(F)c1)NC1CCCC1 +COCCOCC(=O)NC(C)C(=O)N1CCCCC1 +CNS(=O)(=O)c1ccc2[nH]c(C(C)C)nc2c1 +NS(=O)(=O)NC1(c2cccc(Br)c2)CCOCC1 +CCC(C)Oc1ccc(NC(=O)c2cccc(NC(N)=O)c2)cc1 +CCOC(=O)C1CCCC1S(=O)(=O)c1ccc(C)cc1 +CCOc1cccc(CNc2cccc(C(C)=O)c2)c1 +O=C(Nc1ccccc1OCCc1ccccn1)N1CCC(O)C1 +Cc1cc(CN(CC(C)C)S(=O)(=O)c2ccc(C#N)cc2)nn1C +Nc1cc(S(N)(=O)=O)ccc1N1CC2CCC1C2 +CC(C)NC(=O)CCNC(=O)Nc1cccc(Oc2ccccc2)c1 +CN(C(=O)CSc1nnc(-c2cccs2)n1C)c1ccccc1 +O=C(NCc1cccc(F)c1)c1ccc2ncccc2n1 +C#CCN1CCC(C(=O)NC2CCN(C(=O)OC)CC2)CC1 +Cc1cc(C(=O)NCC(=O)Nc2ccc(Cl)cc2)nn1C +CCS(=O)(=O)NC(Cn1cnc2ccccc21)c1ccc(F)cc1 +COc1ccccc1OCC(=O)Nc1sc2c(c1C(N)=O)CCC2 +Cc1cc(=O)cc(C(=O)N2CCC3(CCC(=O)N(C4CC4)C3)CC2)o1 +CCCCn1nc(C(=O)NC(C)c2ccccc2)ccc1=O +COc1ccc(C(O)C(C)NC(=O)C#Cc2ccccc2)cc1 +Cc1nnc(CCCn2c(-c3cccc(F)c3)csc2=O)o1 +Cn1cc(C(=O)N2CCC(OCc3ccccc3)CC2)cn1 +Cc1ccc(C(C)N(C)C(=O)c2nc3nc(C)cc(C)n3n2)cc1 +Cc1oc2nc3c(c(=O)n(CC(C)C)c(=O)n3C)n2c1C +OC(CNCc1ccc2c(c1)OCO2)c1ccc2c(c1)CCC2 +O=C(Nc1ccc(N2CCCC2=O)cc1)c1ccc2[nH]nnc2c1 +COC(=O)CCN(C)C(=O)c1ccc(F)c(N)c1 +CC(=O)NC1CCN(C(=O)Nc2cc(C(F)(F)F)ccc2F)CC1 +Nc1ccc(NCCNC(=O)c2ccc(Cl)cc2)nc1 +CSc1nsc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)n1 +N#Cc1ccc(Cn2nncc2-c2ccc3c(c2)OCO3)cc1 +COc1cc2c(c(OC)c1)C(c1cccc(OC)c1OC)CC(=O)N2 +O=C(C1CCOC1)N1CCC2(CCN(Cc3ccccn3)C2=O)C1 +COc1ncc(C(=O)NC(C)C23CC4CC(CC(O)(C4)C2)C3)cn1 +Cc1cccc(C(=O)NCc2ccc3c(c2)OCO3)c1O +CCC(=O)Nc1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1 +COCCN1CCN(C(=O)c2cc(C(C)C)on2)CC1 +COC(=O)c1ccc2c(c1)CCN2S(=O)(=O)c1c(C)n[nH]c1C +N#Cc1ccc(N2CCC(C(=O)N3CCN(CCO)CC3)CC2)nc1 +Cc1nnc2n1CCN(C(=O)c1cc(-c3ccco3)[nH]n1)C2 +Cc1nc(-c2cc3ccccc3[nH]2)sc1CCO +COc1ccc(-c2ccc3c(c2)OCO3)n2nc(N)nc12 +CC(C)c1nc(CC(=O)Nc2ccc(CNC(N)=O)cc2)cs1 +COc1cc(OC)c(C2NS(=O)(=O)N=C3CCCN32)c(OC)c1 +Cc1nsc(N2CCCN(C(=O)NC3CC3)CC2)n1 +CCC1CN(C)c2ccccc2CN1C(=O)NC(C)c1ccncc1 +CSc1ccc(CN(C)C(=O)NCCNC(=O)C2CC2)cc1 +Cc1cc(C(=O)N2CCCC(C)C2)ccc1NC(=O)c1ccnnc1 +CNC(=O)c1ncn2c(N)c(C(=O)Nc3ccccc3C)nnc12 +O=c1cc[nH]c(C2NCCc3c2ccc(F)c3Cl)c1 +Cn1ncc(N2CCCC(C(=O)NC3CCCC3)C2)cc1=O +COc1c(C)cc(-c2ccc(C(C)=O)cn2)cc1C +CCc1noc(CC)c1CNC(=O)c1cc(C)n(-c2ccccc2)n1 +O=C(NCC(=O)N1CCCC1)Nc1ccc(-c2csnn2)cc1 +COc1ccc(OC)c(COc2ccccc2C(C)=O)c1 +CCOC(=O)CCC(C)NC(=O)c1cc2c(s1)CCCC2 +Cc1cc(Cl)cc2sc(-n3ncc(C#N)c3N)nc12 +CCOc1ccc(NC(=O)CCC(=O)c2cc(C)sc2C)cc1 +COC(=O)c1ccc(C(=O)Nc2cnn(C(C)(C)C)c2)nc1 +CC(C)(C)NC(=O)c1ccccc1NC(=O)C1CC1(Cl)Cl +Cc1cc(C)c(S(=O)(=O)NCC(=O)NCc2cccnc2)c(C)c1 +Cc1c(Cl)cccc1NC(=O)C(C)Sc1ccc(N)cn1 +COC(=O)CS(=O)(=O)Nc1cc(C)ccc1O +CCOCCCNC(=O)Nc1ccc2c(c1)CCO2 +Cc1ccc(CCC(=O)N2CCC(C(N)=O)CC2)cc1Cl +CCCNC(=O)CNC(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +CCOC(=O)c1c(C)[nH]c(NC(=O)Nc2ccc(OCC)cc2)c1C +CN(C)S(=O)(=O)NCc1cc2ccccc2[nH]1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)N3CCOCC3)c12 +Cc1cccc(CNC(=O)c2cn(C)nc2C(C)(C)C)c1 +CCCN(CC1CC1)C(=O)Nc1c(C)cccc1C(=O)N1CCCC1 +Cc1nc(CC(=O)NCC(C)(O)c2ccsc2)cs1 +C=CCNC(=O)c1ccccc1NC(=O)C(C)Oc1cccc(C)c1 +O=C(CCCC(O)c1ccc2c(c1)CCC2)N1CCCCC1 +Cc1ccc(CN2CCOC3C(OCC(=O)N4CCCC4)CCC32)o1 +CCOC(=O)Cn1cnc2c(sc3nc(C)cc(C)c32)c1=O +CCS(=O)(=O)c1ccccc1N1CCC(NC(=O)COC)CC1 +CCC(C)NC(=O)C(C)NC(=O)N(C)Cc1ccc(Cl)c(F)c1 +CCn1c(C)ccc(-c2noc(CCC(=O)NC(C)C)n2)c1=O +Cc1ccc(-c2ncco2)cc1NC(=O)C(C)OCC(F)(F)F +CSc1ccc(CN(C)C(=O)COc2ccccc2F)cc1 +CC(C)COCCCNC(=O)Nc1ccnn1C +CCN(Cc1cccc(C)c1)C(=O)c1ccc(F)cc1 +CC(C)Oc1cccc(CC(=O)Nc2ccc3c(c2)oc(=O)n3C)c1 +CC(C)Cc1nc(CN(C)Cc2nc3ccccc3o2)no1 +Cc1[nH]ccc(=O)c1OCC(=O)Nc1nccs1 +COCCNc1nc2c(OC(C)C)ccc(OC)c2s1 +Cc1nc(N2CCCCC2)ncc1C(=O)Nc1ccc2c(c1)OCO2 +Cc1cc(NC(=O)c2ocnc2C)ccc1Br +COc1ccc(NC(=O)COC(=O)c2ccncc2)c(OC)c1 +CCOc1ccc(S(=O)(=O)NCC2CCC2)cc1 +CCOc1ccc(OCCCN2CCCCS2(=O)=O)cc1 +Cc1ccnc(N2CCc3[nH]nc(-c4ccccc4Cl)c3C2)n1 +CC(=O)NCCNC(=O)C(NC(=O)c1c(F)cccc1F)C(C)C +Cc1cc(S(=O)(=O)Nc2ccc(=O)n(C)c2)c(C)s1 +C=CCn1cc(CN2CCC(O)(c3ccccc3C)C2)c(C)n1 +COc1ccc2ncnc(NCc3ccc(F)cc3)c2c1 +CC1(C)Cc2nc(N3CCOCC3)ncc2C(NC(=O)C2CC2)C1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(F)c(F)c1F +CC(CC#N)N(C)CC(=O)c1cc(F)ccc1O +Cc1cc(C)cc(OCCCN2CCn3c(nn(C)c3=O)C2)c1 +O=S(=O)(NCC#Cc1ccc(F)cc1)c1ccccc1 +Cc1cc(CCNS(=O)(=O)c2cccs2)on1 +Cc1noc(C2CN(C(=O)NCCC(C)C)CC23CCOCC3)n1 +NC(=O)c1n[nH]c2ccc(NCc3cc(-c4ccccc4)[nH]n3)cc12 +O=C(c1ccc(Cl)c2cccnc12)N1CCOCC1 +Cn1nccc1C(=O)Nc1n[nH]c(Cc2ccc(F)cc2)n1 +COC(=O)c1cnc(NC(=O)C(C)OCC(F)(F)F)s1 +O=C(CN1Cc2ccccc2C1=O)NCc1ccc2c(c1)OCO2 +O=C1c2cccnc2CN1CC(CO)Cc1cccs1 +COc1ccc2cc(C3CN(S(=O)(=O)C4CC4)CCO3)ccc2c1 +COc1ccc(C(=O)Nc2nc3c(s2)CCCCC3)cc1OC +CC(=O)Nc1cccc(Nc2c(C)nn(C)c2C)c1 +Cn1cc(C2CCCN2C(=O)c2ccc3c(c2)COC3)cn1 +CC(=O)Nc1ccc(C(=O)OC2CCOC2=O)cc1 +CCCCc1ccc(C(=O)N(CCO)C2CC2)cc1 +CC(C)(C)C(=O)CSc1ncnc2sccc12 +CCC(=O)c1c(CC)nn2c3ccccc3n(C)c12 +COCCNC(=O)CCNc1nn2cc(C)nc2s1 +Cc1cc(N2CCN(CCC(=O)OC(C)(C)C)CC2)nc(C)n1 +O=c1ccccn1CCOc1ccc2ccccc2c1 +Cc1c(C(=O)N(C)Cc2ccc(O)cc2)c(=O)oc2ccccc12 +COC(=O)c1ccc(S(=O)(=O)N2CCOCC2)cc1C +CCc1ccc(CNc2[nH]c(C)c(C)c2C#N)cc1 +COc1ccc(-c2n[nH]c(C3CC3)c2NC(=O)C2CC2)c(OC)c1 +COc1cccc2cc(S(=O)(=O)c3ccccc3)c(=O)oc12 +CC1(C)CN(C(=O)NC(Cn2cncn2)c2ccccc2)C1(C)C +CCOCc1ccccc1CNC(=O)c1csnn1 +CCC(=O)c1ccc(OC(C)C)c(OC(C)C)c1 +CCc1nnc2n1CCN(C(=O)c1ccc3c(c1)OCO3)C2 +COCc1ccc(C(=O)NCc2c(C)cc(C)[nH]c2=O)o1 +Cc1ccc2c(c1)-c1onc(C(=O)Nc3ncccc3C)c1CO2 +COCC(=O)N1CCC2(CC(=O)N(c3cncnc3)C2)C1 +COC(=O)c1ccc(C(=O)N(CCC#N)CCC#N)cc1 +COc1ccc(CNc2nnc(-c3ccccn3)s2)cc1 +CC(C)(C)OC(=O)NCCNC(=O)c1ccccn1 +CCN(Cc1ccc(O)cc1)C(=O)Nc1cnn(CCOC)c1 +CC(=O)Nc1ccc(N2CCCCS2(=O)=O)cc1 +Cc1nsc(N2CCN(C(=O)CCCc3ccccn3)CC2)n1 +CC(C)CCOCCN1CCOC(c2ccccc2)C1 +Nc1c(Br)cccc1Br +COC(=O)c1cc(CSc2nnnn2-c2ccccc2)c(C)s1 +COc1ccc(-c2cc(C(=O)N3CCCC3)c(C)n2C)cc1 +CC(C)n1nnnc1-c1cccc(C(=O)N2CCCCC2)c1 +CCc1cc2c(=O)n(CCC#N)c(Cc3ccccc3)nc2s1 +CCC(C)N(Cc1ccsc1)C(=O)c1ccc(-n2cnnc2)cc1 +COc1cccc2c1C(c1cccnc1F)NCC2 +COC(=O)c1ccc(Cl)c(S(=O)(=O)NCC2CCCOC2)c1 +COc1cccc(C(=O)N2CCN(Cc3cc(C)no3)CC2)c1F +Cc1noc(C)c1CNC(=O)c1nc2ccccc2c(=O)[nH]1 +Cc1ccc2nc(SCC(=O)NCC(F)(F)F)[nH]c2c1 +CN(CCOc1ccc(F)cc1)S(=O)(=O)c1ccccc1 +COc1ccccc1CN(C)c1ncnc2c1cnn2C +CCN(CCC(=O)OC)C(=O)C1CCCc2ccccc21 +O=C(c1csc(-c2cccs2)n1)N1CCCC1Cn1cccn1 +Cc1ccc(Cl)cc1-n1ccn(CC(N)=O)c(=O)c1=O +COCC(=O)N1CCN(c2cc(-n3cccn3)nc(C)n2)CC1 +O=C(NCCc1nc[nH]n1)c1ccc(-n2ccnn2)cc1 +COCCCNC(=O)C1c2ccccc2CCN1C(C)=O +CC(C)C(NC(=O)c1ccncc1)c1cc(=O)[nH]c(-c2ccccn2)n1 +CC(=O)NCc1ccc(-c2csc(C)n2)s1 +COc1ccccc1CC(=O)NCc1noc(-c2ccccc2)n1 +N#CC1(C#N)C(C(=O)c2ccccc2)C12CCOCC2 +O=C(Nc1cncnc1)OCC(Cl)(Cl)Cl +CCn1cc2c(n1)C(COC)CN(Cc1ccc(F)cc1)C2 +Cc1ccc(S(=O)(=O)N2CCSc3ccncc32)cc1F +Cc1cccc(OCC(=O)NCc2ccc(N3CCCC3=O)cc2)c1 +O=C(CNc1cccc(C(=O)NCc2ccco2)c1)Nc1ccccc1 +O=C(NCCCN1CCCC1=O)c1cnc(N2CCCC2)nc1 +Cc1cc(C)n(CC2CN(Cc3nc(C4CC4)no3)CCO2)n1 +CC(NC(=O)c1ccccc1N)c1ccccc1Br +NC(=O)C1CC(=O)N(c2ccc3oc(-c4ccc(F)cc4)nc3c2)C1 +C=CCNC(=O)CSc1nnc(-c2ccc(F)cc2)n1N +CCOCCCNc1nc2c([nH]1)c(=O)n(C)c(=O)n2C +Oc1ccc2cc(CNc3nccs3)ccc2c1 +CN1C(=O)CN(C(=O)C2CCOCC2)c2ccccc21 +N#Cc1ccc(CS(=O)(=O)N2CCCc3ccccc32)cc1 +CCOCCCNC(=O)c1nnn(-c2ccc(C)c(F)c2)c1C +Cc1nc(CC(=O)NCCc2nc3ccccc3[nH]2)cs1 +CCC(NC(=O)c1ccc(NC(=O)C2CC2)s1)c1ccc(C)cc1 +COCC(C)NC(=O)c1oc2c(Cl)cccc2c1C +Cc1cc(C)n(-c2ccc(CNC(=O)N(C)CC3CCCC3)cn2)n1 +CC(C)C(=O)Nc1ccc2c(c1)NC(=O)C(C)(C)O2 +CCCN1CCN(C(=O)C2Cc3ccccc3N2C(=O)CC)CC1 +N#CCCCS(=O)(=O)N1CCCC1CC(=O)c1ccc(F)cc1 +CN(CCOc1cccc(Cl)c1)C(=O)c1ccc(C#N)cc1 +O=C(CNc1ccc(-n2cccn2)c(F)c1)NC1CC1 +O=C(NCCCn1cccn1)c1ccc(C(F)(F)F)cc1 +O=C(Cc1cccs1)NCC#CCOc1cccnc1 +Cc1cc(Cl)c2oc(C(=O)N(C)CCc3noc(C)n3)c(C)c2c1 +CCCn1ncc(C(=O)NCc2cc(F)c(F)cc2F)c1C +COc1ncccc1CNC(=O)CCC1CCCO1 +O=C(Nc1nnc(C2=COCCO2)o1)c1ccccc1 +COc1ccc(NC(=O)Nc2nnc(-c3ccn(C)n3)o2)c(OC)c1 +COc1ccc(-c2cncc(C(=O)NCc3ccccc3)c2)cc1 +C#CCNC(=O)COc1cccc(Br)c1 +CNC(=O)c1nn(C)cc1NS(=O)(=O)c1cnn(C)c1 +CCn1cc(C(=O)N(C)CC2CCCO2)c(=O)c2cc(Cl)ccc21 +O=C(NC1CCN(c2nccs2)CC1)c1nc2ccccc2s1 +COc1nc2ccn(Cc3nnc(C)o3)c(=O)c2cc1C#N +CN(C)c1ncccc1-c1nc2ccccc2s1 +Cc1ccccc1CNC(=O)CN1CCOCC1(C)C +Cn1nc2n(c1=O)CCN(Cc1ccccc1Oc1ccccc1)C2 +N#CCC(=O)NCCOc1ccc2cc(Br)ccc2c1 +Cc1ccc(CC(=O)NCCc2nnc3n2CCCCC3)cc1 +COCC1CCCN(C(=O)c2cc(C3CC3)on2)C1 +CCn1cnnc1CNC(=O)c1csc(NC(C)=O)n1 +COc1ccc2c3c([nH]c2c1)C1(NCC3)C(=O)Nc2ccccc21 +COc1cccc(C(=O)OCC(=O)Nc2cccc(C)c2)c1O +CC(C)(C)C(=O)N1CCCC(C(=O)Nc2c(F)cccc2F)C1 +CC(O)CN1CCN(C(=O)COc2ccccc2C(F)(F)F)CC1 +N#Cc1nccnc1NC1CCOC2(CCCCC2)C1 +CCC(C)(C)NC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +CC(=O)Nc1cc(C(=O)Nc2c[nH]nc2C)ccc1C +CCn1c(=O)n(CC)c2cc(C(O)CC(C)C)c(C)cc21 +CN(CC(=O)Nc1nncs1)c1ccc(F)c(F)c1 +Cc1cnc(N2CCC(C)CC2)c(Br)c1 +CCc1cnc(N)nc1N1CCC(N2CCOCC2)CC1 +CC(C)C1(O)CN(C(=O)CCCn2cncn2)CC1C +CC(=O)Nc1cccc(NC(=O)C(C)Nc2cccc(C(C)=O)c2)c1 +Cc1nnc(-c2cccc(C(=O)N(C)c3cccc4ncccc34)c2)o1 +COc1ccc(CNC(=O)N(C)Cc2nccn2C(F)F)cc1F +CC(NC(=O)NCCOc1ccccc1)C(=O)N1CCCCC1 +COc1ccc(C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)cc1 +Cn1nnnc1SCC(=O)Nc1cc(F)c(F)cc1F +CCN(CC)c1cc(N2CCN(C(=O)OC(C)(C)C)CC2)ncn1 +CCOc1cccc(C(=O)N2CCN(c3ccccc3F)CC2)c1 +Cc1cc(=O)c2cc(NC(=O)c3ccc(COC(C)C)o3)ccc2[nH]1 +CC1CCc2c(sc3ncnc(-n4cnnc4C#N)c23)C1 +CCn1ncc(S(=O)(=O)Nc2ccccc2C(N)=O)c1C +CC(C)c1ncc2c(n1)CN(c1cccc(F)c1C#N)CC2 +Cc1occc1C(=O)NCC(=O)NC(C)c1oc2ccccc2c1C +CCc1cc2c(N3CCOCC3)nc(C)nc2s1 +Cc1ccc(-c2nnc(COC(=O)c3ccco3)o2)cc1 +CCC1CN(Cc2ccncc2)CCC(=O)N1Cc1ccccc1 +Cc1cc(C)n(CC2CCCN2C(=O)Cc2n[nH]c3ccccc23)n1 +CCOC(=O)c1sc2nc(C)nc(C)c2c1N +O=C(CN1CCN(c2ccc(F)c(F)c2)C1=O)NC1CCCC1 +CN(C)c1ncnc(Nc2cc(F)ccc2F)c1N +Cc1cccc(-c2[nH]ncc2CNC(=O)Cc2ccccc2F)c1 +O=C(Cn1nnc(-c2ccccc2)n1)NCCc1nnc2ccccn12 +CN(C)C(=O)N1CCN(C(=O)NCC2(c3ccccc3F)CC2)CC1 +COc1cc(NS(=O)(=O)c2c(C)n[nH]c2C)ccc1N +COCCCC(=O)Nc1ccn(Cc2ccccc2)n1 +Cc1nnc2sc(-c3ccccc3N)nn2c1=O +CCNC(=O)CNC(=O)c1cc(CC(C)C)n[nH]1 +O=c1c2ccsc2ncn1Cc1noc(C2CCC2)n1 +O=C(Cc1ccc(F)cc1)Nc1ccc(CC(=O)N2CCCC2)cc1 +O=C(Cn1ccccc1=O)N1CCC(c2nnc3n2CCC3)CC1 +CC(NC(=O)c1cc[nH]n1)c1nc(-c2ccncc2)cs1 +CC1CN(C(=O)CSc2nc3ccccc3o2)CC(C)O1 +COC(C)(c1ccccc1)n1nnc2ccccc21 +CCCC(O)c1cc2c(cc1NC(=O)c1cccs1)OCCO2 +Cc1c(NC(=O)N2CCCC2)cccc1C(=O)N1CCOCC1 +CS(=O)(=O)N1CCN2C(=O)N(C3CCOCC3)CC2C1 +COc1ccc2cc(C(=O)Nc3ccc(-c4nnco4)cc3)[nH]c2c1 +CC(=O)N(CCC(=O)NC(C)CC#N)Cc1ccccc1 +O=C(NCc1ccc2c(c1)OCO2)c1cccc(Cn2cccn2)c1 +O=C(c1cncnc1)N1CCC(c2nc3ccccc3o2)C1 +N#Cc1ccc(CNC(=O)NCC(O)c2ccc(Cl)c(F)c2)cc1 +COc1ccccc1C(=O)OCC(=O)NCc1ccccc1C +Cc1nc(C(C)(C)C)sc1C(=O)Nc1nc(CC(N)=O)cs1 +COc1ccc(-c2csc(NC(=O)c3ccc(C)o3)n2)cc1 +Cn1cc(C(=O)N2CCN(C(=O)c3cccc(F)c3)CC2)cn1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3ccon3)cc12 +O=S(=O)(c1c[nH]cn1)N1CCC(c2c[nH]c3ncccc23)CC1 +Clc1cccc(NCc2cnn(-c3ccccc3)c2)c1 +COc1nc(C)cc(C)c1CNC(=O)NCCc1nc(C(C)C)no1 +CCN(Cc1ccccc1C#N)C(=O)c1cc(C)n[nH]1 +O=S(=O)(c1cnccc1Cl)N1CCOCC1 +CCOC(=O)c1cn(Cc2ccco2)c2cccc(N)c2c1=O +CNC(=O)Cc1ccc(NC(=O)NCc2cccc(F)c2)cc1 +COc1cc(C(=O)NCC2CCOC2)ccc1OCC(N)=O +COc1cccc2cc(C(=O)NCc3cccc(NC(C)=O)c3)oc12 +O=C(Cc1ccc[nH]1)NCc1cccc(OCc2ccccc2)c1 +CCC(O)CN1CCN(C(=O)C(C)N2CCOCC2)CC1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCC2(CC1)OCCO2 +CC1(NC(=O)Nc2ccsc2)Cc2ccccc2C1 +CC(C)Nc1nc(NCCCO)nc2c1cnn2C +CC(=O)c1ccc(NC(=O)C(O)c2ccc(Cl)cc2)cc1 +O=C(CC1Oc2ccccc2NC1=O)NCc1ccc2c(c1)OCO2 +Cc1ccc(C)c(S(=O)(=O)Cc2nc(N)nc(N(C)C)n2)c1 +CCOCCC(=O)N1CCC(C)Sc2ccc(Cl)cc21 +CCCOc1cc(C)nc2cc(C3CCOCC3)nn12 +CC(NS(=O)(=O)c1ccccc1)c1ccc(-c2cncnc2)cc1 +O=C(Cc1c[nH]c2cc(F)ccc12)N1CCc2cc(F)ccc2C1 +CCCCOc1ccc(C(=O)NCCC)cc1N +CCCNC(=O)Cn1cnc2c(C)cccc2c1=O +CC(C)NC(=O)Nc1nc2c(s1)CN(C(=O)c1ccccc1)CC2 +CC1CN(CC(=O)NC2CCCC2)c2c(N)cccc2O1 +CCOc1cc(C)c(C(=O)CNC(=O)c2ccco2)cc1C +C=CCN1CC2=C(C1=O)C(c1ccc(OC)cc1)NC(=O)N2 +COc1cccc(CC2CCCN2C(=O)c2ccc(C)[nH]c2=O)c1 +CC(C)NC(=O)Nc1cccc(C(=O)NC(C)CN2CCCC2=O)c1 +C=CCN1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1 +COC(=O)CN(C(=O)c1ccc2sccc2c1)c1cccc(C)n1 +Cc1cccc2c1NC1(NC2=O)C(=O)Nc2ccc(F)cc21 +Cc1noc(COC(=O)CCc2ccc(C(C)C)cc2)n1 +Cc1noc(C)c1S(=O)(=O)NC(Cc1ccccc1)C(N)=O +OCCNc1cc(N2CCCC(CO)(CC3CC3)C2)ncn1 +Cc1c(C)n(CCc2ccccn2)c2ncnc(NC(=O)C(C)C)c12 +O=C(CSc1nnc(COc2ccccc2)o1)Nc1nncs1 +COc1ccccc1-c1c(C)oc2cc(OC(C)=O)ccc2c1=O +COC(=O)c1ncn(CCCc2cccc3ccccc23)n1 +Cc1ccc(C)c(OCc2nnc(SCCC#N)o2)c1 +Cc1ccnc(Nc2ncnc(NCCC(C)C)c2N)c1 +Cn1c(N)nnc1SCc1cc(Br)ccc1F +N#CCCN(Cc1ccccn1)Cc1ccccc1-n1cccn1 +Cc1nccn1-c1ccc(CNC(=O)c2c(O)cccc2O)cc1 +CN(C(=O)c1cccs1)C(c1cccc(F)c1)c1ccccn1 +Cc1nc(SCC(=O)N2CCc3ccccc3C2)c2ccccc2n1 +CC1=C(C(=O)N2CCCC(CCC(=O)NC3CC3)C2)OCCO1 +Nc1ccnc(C(=O)Nc2ccc3c(c2)OCCO3)c1 +Cc1ccc(-n2nnnc2SCC(=O)Nc2ccncc2)cc1 +Cc1csc(NC(=O)C2CCN(c3ccc4nncn4n3)CC2)n1 +C=CCn1c(C)nnc1SCC(=O)c1ccc(F)cc1 +CCCCn1nccc1NC(=O)C1CC(=O)N(Cc2ccco2)C1 +NC(=O)C1(NCc2csc(-c3ccc(F)cc3)n2)CCCCC1 +CC(C)N(CCCO)c1ccc2scnc2c1N +COc1ccccc1C(=O)NCC(=O)NCc1ccco1 +CCC1CCCN(C(=O)c2ccc(CNC(C)=O)cc2)C1 +CC(=O)Nc1ccc(NC(=O)c2cccn2C)cc1 +COC(=O)CCCOc1ccccc1NC(C)=O +O=C1COC2CN(Cc3ccc(F)cc3)CC2N1CC1CC1 +Cc1cc(NCCC(C)O)ncc1Br +CCCNC(=O)CCNC(=O)Nc1ccccc1-n1nc(C)nc1C +C=CCN(CC=C)C(=O)CN1CCN(c2ncccn2)CC1 +Cc1nc(SCC(=O)N2CC(C)OC(C)C2)c2ccccc2n1 +O=C(CCc1cccs1)Nc1cccc(Oc2ncccn2)c1 +O=C(OCCc1ccc(F)cc1)C1CCOCC1 +COCCSc1ccccc1C(=O)N1CCc2ccccc21 +Fc1ccccc1CNCc1ncc(-c2ccsc2)s1 +CC(C)N(C(=O)CCn1cnc2sccc2c1=O)C1CCOCC1 +CN(Cc1ccccn1)C(=O)NC1CCSc2ccc(Cl)cc21 +CCCc1nc(CSc2nc(N)cc(N)n2)no1 +Cc1ccc(CNC2(Cc3cc(-c4cccc(O)c4)on3)COC2)o1 +CC(C)COc1ccc(CC(=O)N2CCN(C(=O)CO)CC2)cc1 +Cc1ccc(N2CCCC2=O)c(C(=O)NCc2cnn(C)c2)c1 +N#Cc1cccc(CNC(=O)Nc2ccc(Cl)c(F)c2)c1 +CCOC(=O)c1c(N)nc(=O)n(-c2ccccc2)c1C +Nc1ccc(Cl)c(-c2cc(=O)c3cc(F)ccc3o2)c1 +Cc1cc(CS(=O)(=O)Nc2ccc(N)c(C)c2)no1 +Nc1cn(Cc2ccccc2)cc1-c1cn2ccnc2o1 +CC(=O)NCCc1nc2ccccc2n1CC(=O)N(C(C)C)C(C)C +CNC(=O)CSc1nnc(-c2ccc(N(C)C)cc2)n1C +CCN(Cc1ccccc1)C(=O)C1CCN(S(=O)(=O)CC)CC1 +C#CCN(Cc1ccco1)C(=O)Nc1ccccn1 +CC(C)CN(c1cc2c(cc1N)CC(=O)N2)C1CC1 +COc1cccc(C(=O)NCC(=O)NC2(C)Cc3ccccc3C2)c1 +CC(NC(C(=O)NC1CC1)c1ccccc1)c1ccc2c(c1)OCO2 +O=C(C(O)c1ccc(F)cc1)N1CC(c2ccncc2)C1 +N#CC1(NC(=O)Cn2nnn(-c3ccccc3)c2=O)CCCC1 +CCSc1cncc(NC2CCN(c3ncccn3)CC2)n1 +N#CCCN(CCC(F)(F)F)Cc1cnc2cnccn12 +Cc1cc(C(=O)NCCN2CCCc3ccccc32)n(C)n1 +Cc1ccc(NC(=O)Cc2c(C)nc(-c3ccccn3)[nH]c2=O)nc1 +COCc1nc(C(=O)Nc2cc(CCc3ccccc3)n[nH]2)cs1 +Cc1ccc(C2COCCN2Cc2sc(N(C)C)nc2C)o1 +CC(C)n1nccc1NC(=O)Cc1ccccc1F +Cc1ccc(Nc2nc(C)c(-c3ccnc(N)n3)s2)cc1 +CNC(=O)CN1CCN(C(=O)CCCc2cccs2)CC1 +Cc1cnn(C2CCCN(C(=O)C3CC3c3cnn(C)c3)C2)c1 +N#CCCn1c(-c2cccnc2)nc2cc(Cl)c(Cl)cc21 +O=C(CCS(=O)(=O)c1ccc(Cl)cc1)c1ccc(F)cc1 +Cc1cc(F)ccc1CCNC(=O)c1ccsc1 +COc1ccc(SC(C)C(=O)NCc2nc3ccccc3[nH]2)cc1 +Cc1ccc(OCC#CCNC(=O)Nc2cccs2)cn1 +CCN(CC)C(=O)c1ccc(-c2cccs2)[nH]c1=O +Cc1cc2nnc(SCC#N)n2c2ccccc12 +O=C(c1ccc(-c2nc[nH]n2)cc1)N1CCC1c1ccc(F)cc1 +Cc1nnc(C23COCC2CN(S(=O)(=O)c2cn(C)cn2)C3)o1 +N#Cc1ccc(CNC(=O)NCCCN2CCOCC2)cc1 +COc1ccc(C(C)C)cc1S(=O)(=O)NCCCO +CCOc1ccc(C(=O)Nc2ccccc2C(F)(F)F)nn1 +Cn1ccnc1CN1CCC2C1CC(=O)N2Cc1cccnc1 +CSc1nc(-c2ccco2)nc(C)c1C(=O)OCC1CCCCO1 +CCN(CC)C(=O)c1ccccc1NC(=O)NCc1ccc(F)cc1 +Cn1c(=O)c2[nH]c(CN3CCOc4cccc(F)c43)nc2n(C)c1=O +O=C(NCc1ccc(-n2cncn2)cc1)c1ccccc1OC(F)F +Cc1ccc2c(c1)N(Cc1ccc(C(=O)N3CCCC3)o1)C(=O)CO2 +CNC(=O)NCC(=O)Nc1cc(Cl)ccc1-n1cccn1 +N#Cc1ccccc1S(=O)(=O)NC1CCCCCC1 +Cc1ncsc1C(=O)NC(C)(C)c1cccc(F)c1 +Cc1ccccc1-c1csc2c(=O)n(Cc3ccccn3)cnc12 +Cc1ccc(-n2nc(C(=O)Nc3ccc(Cl)cc3)nc2C)cc1 +COC(=O)C(C)Sc1nncn1-c1cccc(NC(C)=O)c1 +Cc1cc(C)n(-c2ccccc2NCc2ccc(C#N)cc2)n1 +CC1CCCCC1NC(=O)Cn1ncn2c(cc3ccsc32)c1=O +CC(C)CC(C(=O)NCC(=O)N1CCCC1)N1CCCCC1=O +C=CCSc1nnc(NC(=O)c2snnc2CC)s1 +CC(C)CNC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CC(C)(C)OC(=O)N1CCN(c2c[nH]c3ncccc23)CC1 +O=C1Nc2ccccc2C12CCN(S(=O)(=O)c1cccs1)CC2 +COc1ccc(CN(C(=O)CCc2nc3ccccc3[nH]2)C2CC2)cc1 +COc1ccc(C(=O)CNC(=O)c2c(F)c(F)cc(F)c2F)cc1 +c1cc2c(cc1CNc1nnc(C3CCC3)o1)CCCO2 +CS(=O)(=O)NCc1cn2c(n1)CN(C(=O)c1ccno1)CC2 +Cc1cccc(OCCN2CCN(C(=O)C3CCCO3)CC2)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cc(F)c(F)c(F)c1F +O=C(Cc1nc2sc3c(c2c(=O)[nH]1)CCCC3)c1ccco1 +O=C(NCc1cccc(F)c1)NC1CCC(O)CC1 +Cc1nc(Cc2c[nH]c3ccccc23)nc(C)c1N +COCCn1cc(NC(=O)N2CCC(C(N)=O)CC2)c2ccccc21 +CCC(CC)c1nnc(NC(=O)N(C)Cc2c(C)noc2C)s1 +COc1ccc(CCNc2ccn3nc(N)nc3c2)cc1 +CC(C)(C)OC(=O)N1CCC(Sc2cccc3nccn23)CC1 +CC(Nc1cnn(C)c1)c1ccc(Cl)c(Cl)c1 +Cn1ccc2c(C(=O)N3CCCC3c3ccccn3)cccc21 +CN(C)C(=O)n1nc(-c2ccc(F)cc2F)oc1=O +COC(=O)C(C)Sc1ccccc1C(=O)N(C)C1CCCC(C)C1 +COc1ccc(COc2nc(-c3cnccn3)nc(C)c2C)cc1F +Nc1nccnc1-c1nc(-c2cccc(Cl)c2)no1 +CC(=O)Nc1cccc(NCC(=O)NCc2ccc(F)c(C)c2)c1 +COC(CNS(=O)(=O)c1c(C)cc(C)cc1C)c1ccsc1 +Cc1ccc(Sc2ncccc2C(=O)Nc2nnc[nH]2)c(C)c1 +Cc1ccc(S(=O)(=O)N=c2ccccn2CC(N)=O)cc1 +CN(Cc1ccc(C(F)(F)F)cc1)C(=O)Cn1ccccc1=O +O=C(CSc1nncs1)Nc1cnn(-c2ccccc2F)c1 +NC(=O)c1cccc(CNc2ccccc2C(F)(F)F)c1 +COc1cccc(OC)c1C(=O)NC(CO)c1ccccc1 +CCc1cc(NCCc2nc3ccccc3c(=O)[nH]2)n2nccc2n1 +CS(=O)(=O)N(CC(=O)Nc1ccccc1)c1ccccc1F +CCOC(=O)C1(NC(=O)c2ccc(C)c(NC(C)=O)c2)CCCC1 +O=C1CCC2(CCCO2)CCN1Cc1ccc2ccccc2n1 +CC(C(=O)Nc1ccccc1)N1CCN(c2ccc(F)cc2)CC1 +CCOC(=O)Cn1c(=O)n(CCOC)c2ncccc21 +Cc1n[nH]c(C)c1NS(=O)(=O)c1csc2ccc(Cl)cc12 +O=C(Nc1nc2c(c(=O)[nH]1)CCCC2)c1ccc(F)cc1 +Nn1c(SCc2c(F)cccc2Cl)nncc1=O +COc1cc(NC(=O)Cc2cccs2)ccc1N1CCCC1=O +Cc1cc(C)c(C(=O)N(C)Cc2ccccc2Br)c(=O)[nH]1 +CCOc1ccc(OCC)c(NC(=O)c2cc(C(N)=O)cs2)c1 +CC(=O)Nc1nc(C(=O)N2CCCCC2C)cs1 +Cn1cc(C(=O)NCCc2cccc(O)c2)c(C(C)(C)C)n1 +c1cncc(CN2CCOC3(CCCN(c4nccs4)C3)C2)c1 +NC(=O)C1CN(C(=O)Nc2cc(F)ccc2F)CCO1 +COc1ccc(-c2nc3scc(N)n3n2)c(OC)c1 +CNC(=O)c1ccccc1-c1ccc(CNS(C)(=O)=O)cc1 +CCc1ccc(C(=O)Nc2cnn(C(C)(C)C)c2)o1 +O=C(CNC(=O)c1ccccc1)NCc1cccc(Cl)c1 +C#CCN(CC#C)C(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +Cc1nc(C(=O)Nc2c(C)cccc2C)c(-c2ccccc2)s1 +CC(=O)Nc1ccc(NC(=O)Nc2cccc(Br)c2)cc1 +Cc1cccc(C)c1OCc1cc(=O)n(C)c(=O)n1C +CC(C)C(=O)N1CCCC1C(=O)N(C)Cc1nccn1C(F)F +O=c1[nH]nc(Cn2nc(-c3ccc(F)cc3)oc2=O)[nH]1 +CC(C)CC(C)NC(=O)COc1ccccc1N +CSc1ccccc1NC(=O)NC1CCN(C(=O)CC(C)C)CC1 +COC(=O)Cc1csc(NC(=O)C2COCCO2)n1 +Cc1ncc(CNc2cnn(-c3ccccc3F)c2)s1 +COC(=O)c1sc(NC(=O)Cn2ccnn2)nc1C1CC1 +COCCCn1ccc(NC(=O)NC(C)c2ccncc2)n1 +Cc1nc(CS(=O)(=O)c2ccccc2)[nH]c(=O)c1CCO +COC(C)(C)CC(C)NC(=O)NCc1cn2ccsc2n1 +Cc1cc(C)cc(C(=O)N2CCCC(c3nc4ccccc4[nH]3)C2)c1 +COCCn1c(-c2ccc(OC)c(C)c2)ccc(N)c1=O +Cc1ccc(F)c2c1N(C(=O)c1cccc(-n3cnnn3)c1)CCC2 +Cn1ccc2c(-c3nc(-c4ccc(C#N)cn4)no3)cccc21 +CC(NC(=O)CCSc1nc2ccccc2s1)C(N)=O +CC(NC(=O)CSc1ncnc2sccc12)c1ccco1 +COc1cccc(CC(=O)NCCc2cnn(-c3ccccc3)c2)c1 +CCNS(=O)(=O)c1ccc2c(c1)C(C)(C)CC(=O)N2C +c1coc(-c2nn3c(C4COc5ccccc5O4)nnc3s2)c1 +Cc1n[nH]c(-c2cccc(CNC(=O)COc3ccccc3O)c2)n1 +CC(C)C(NC(=O)Cc1ccccc1)C(=O)N1CCC(C(N)=O)CC1 +CC(C)CC(C)NC(=O)c1cccnc1OCC(F)F +Cc1cc(C)nc(C(C#N)C(=O)Cc2ccc(F)c(F)c2)n1 +Cc1noc(C)c1CC(=O)NCc1cccc(N2CCCC2=O)c1 +O=S(=O)(Nc1ccc2[nH]ncc2c1)c1cccc(C(F)(F)F)c1 +COC(=O)Cn1cc(NC(=O)c2ccc(C)c(O)c2)cn1 +Cc1nn2c3ccccc3n(C)c2c1C(=O)OCCN1CCOCC1 +O=C(c1cn(-c2cc(Nc3ccccc3)ncn2)cn1)N1CCCC1 +O=C(CCCc1cc(F)ccc1F)N1CCOc2ncccc21 +COc1ccc(C(O)CCC(=O)NCc2ccncc2)cc1 +O=C(CC1(Cn2cnnn2)CCCCC1)NCC1CCOCC1 +CCNc1nnc(S(=O)(=O)CC(=O)NCC2CCC2)s1 +CC(=O)c1ccc(NCC(=O)N2CCSc3ccccc32)cc1 +COc1cc(CNC(=O)c2ccc(CNC(C)=O)s2)ccn1 +CCOc1ncccc1CNC(=O)c1cccc(OC)c1 +Cc1cccc(-n2cnc(C(=O)Nc3ccc(F)cc3)n2)c1 +Cc1ccc(NC(=O)N(CCO)Cc2ccsc2)c(Cl)c1 +CCC1CCc2nc(N)c(C#N)c(-c3cn(CCO)nc3C)c2C1 +O=C(NCc1ccncc1)c1ccc(-c2ccc(Cl)cc2)[nH]c1=O +O=c1c2ccccc2cnn1CC(O)c1ccc(F)cc1F +Cc1cc(=O)c(O)c(CN(C)CCO)n1Cc1cccnc1 +CC(Sc1nnc(-c2ccccc2)n1C)C(=O)Nc1ncccn1 +CCOC(=O)C(NC(=O)Nc1cc(C)ccn1)(OC)C(F)(F)F +CC1CSc2ccc(Br)cc2C1=O +Cc1nc2cc(O)nn2c(C)c1CCC(=O)NCc1ccncc1 +O=C1CCC(NC(=O)Nc2cccc3cccnc23)CN1 +CC1(C)CC(=O)c2c(oc(N)c2C(=O)c2ccccc2)C1 +CC1CCN(C(=O)CSc2ccc(-c3ccncc3)nn2)CC1 +CCCCS(=O)(=O)N1CCc2nc(NC(=O)OC)sc2C1 +O=C(COc1ccccc1)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1cc(C(O)Cc2ccccc2)cc2c1NC(=O)C2C +COc1ccc(S(=O)(=O)NC2CC2)cc1C(=O)N1CCCC1 +CCN(C(=O)CCc1cc(OC)c(OC)cc1N)c1ccccc1 +CC(=O)N1CCc2ccccc2C1CC(=O)Nc1cc(C)nn1C +O=C1OC(CC(=O)N2CCc3ccc(Cl)cc3C2)c2ccccc21 +O=C(NCCN1CCCS1(=O)=O)C12CC3CC(CC(C3)C1)C2 +O=C(OCc1ccccc1C(F)(F)F)c1cc[nH]n1 +CC(C)C(=O)Nc1ccc(NC(=O)c2cccn2C)cc1 +N#CCC(=O)NCCCOC(=O)Nc1ccc(Cl)c(Cl)c1 +CC1CCCN(C(=O)C2CN(C(=O)c3cnccn3)C2)C1 +CCOc1ccc(-n2nc(C(C)(C)O)c(=O)cc2C)cc1 +O=C(COc1ccccc1)Nc1ccccc1N1CCCC1 +CCOc1ccc(C(=O)N(C)C2CCCCC2)cc1OC +CN(Cc1ccco1)C(=O)COC(=O)c1ccc(-n2cccn2)cc1 +Cc1ccc(C(=O)OCC(=O)Nc2ccc(F)cc2Cl)cn1 +CCCc1noc(C(C)Nc2cccc(N3CCOC3=O)c2)n1 +Cc1nnc(COc2ccc(NC(=O)CC(C)(C)C)cc2)o1 +Cc1ccc(C(=O)CCC(=O)NCc2ccccc2-n2ccnc2)cc1 +O=C(NCCc1ccccn1)Nc1cccc(Cl)c1Cl +O=C(NCC1(c2ccc(F)cc2F)CC1)c1cc(Cl)c[nH]1 +COc1ccc(N(C)C(=O)Cc2noc3ccccc23)cc1OC +Cc1ccccc1CC(=O)NCCc1ccccc1 +CC(C)C(NC(=O)c1cccs1)C(=O)N(C)CCc1ccccc1 +CCOc1ccc(N2CC(NC(N)=O)CC2=O)cc1 +CCCc1nc(NCC(C)C)c2c(n1)c(C)nn2CC +CCOc1ccc(C(=O)NC(C)c2c(C)noc2C)cc1OCC +C=CCN(CC=C)C(=O)C(C)Sc1nc(N)c(C#N)cc1C#N +Cc1ccc(NC(=O)CN2C(=O)CN(C)C(=O)c3ccccc32)nc1 +Cc1cnc(NC(=O)c2cn(C)c3ccccc23)s1 +CNC(=O)CSc1nc(N)c(NC(=O)c2ccco2)c(=O)[nH]1 +CC(C)Oc1ccc(C#N)cc1NC(=O)C1CCC(=O)N1 +Cc1cc(C)n2nc(C(=O)NC3c4ccccc4CC3C)nc2n1 +Cc1ccc(Cl)cc1-c1cc(CO)c(=O)n(C)n1 +CCOc1ccc(C(=O)COC(=O)c2ccc(N)cc2)cc1 +Cc1ccc(C(=O)N(C)C)cc1OS(C)(=O)=O +O=C(CCc1ccncc1)N1CCOC(CC2CCCCC2)C1 +Cc1ccc(NC(=O)c2ccn(C)c(=O)c2)c(Br)c1 +O=C1CCC(C(=O)NCC(c2ccc(F)cc2)N2CCOCC2)N1 +COC(=O)CCN(C)C(=O)c1ccc(N)cc1Cl +O=C(COC(=O)c1c[nH]c2ccccc12)Nc1ccc(F)cc1 +COC(=O)c1ccc(COC(=O)c2ccc3c(c2)OCCO3)cc1 +Cc1ccc(N2CCCN(CC3=CCCOC3)CC2)nn1 +O=C(Nc1ccc(Cl)c2ncccc12)c1ccncc1 +CC(=O)NCC(=O)Oc1ccc(NC(=O)c2cccs2)cc1 +O=C(NC1CCCN(Cc2ccccc2)C1=O)c1ccc[nH]1 +Cn1c(Oc2cc(Cl)cc(Cl)c2)cc(=O)n(C)c1=O +O=C(c1ccc2[nH]nnc2c1)N1CC(Oc2ccccc2Cl)C1 +COC(=O)C(C)(NCC(F)(F)F)c1ccc(O)cc1 +CCc1cccc(NC(=O)NC(C)C(=O)NC(C)CC)c1 +COCc1cc(NCCc2c[nH]c3ccccc23)ncn1 +Cc1n[nH]c(NC(=O)c2ccc(COCC(F)(F)F)cc2)c1C +Cc1occc1C(=O)OCc1nnc(-c2ccccc2Cl)o1 +CC(C)(C)C(NC(=O)NCc1cscn1)c1cccs1 +CC(CC#N)N(C)c1ccc(Br)cc1 +CCOC1CC(N(C)C(=O)Nc2cnccc2C)C12CCC2 +Cn1cc(CCNC(=O)NCc2ccc(F)c(Cl)c2)cn1 +CCCn1c(C)nnc1SCc1csc(NC(C)=O)n1 +Cc1ccccc1CN(c1ccc(C(=O)N(C)C)cc1)S(C)(=O)=O +N#CCS(=O)(=O)c1ccc(Br)cc1 +Cc1ccccc1-n1cc(C(=O)NC(C(N)=O)C(C)(C)C)cn1 +O=C(c1cc2cc(Br)ccc2[nH]1)N1CCC1 +CC(=O)NCC1CCCN(c2ccc(C#N)cn2)C1 +COC(=O)C1(NS(=O)(=O)c2cc(C)sc2C)CCCC1 +CN(C)c1cc(C(=O)NC(C)(C)c2ccc3c(c2)OCO3)ccn1 +COc1cccc(NC(=O)Nc2sc3c(c2C(N)=O)CCCC3)c1 +Cc1cc(=O)c(O)c(CN2CCC3(CC2)OCCO3)n1C +Cc1ccc(C(C)NC(=O)Cn2cnnn2)cc1F +Cc1ccc(C2(O)CCN(C(=O)c3cccc4c3OCC4)CC2)nc1 +Cc1n[nH]c(-c2ccc(NC(=O)c3csnn3)cc2)n1 +Cc1ccc(NC(=O)Cc2cn3ccsc3n2)c(Cl)c1 +CN(Cc1cccc(Br)c1)C(=O)C1CCCOC1 +CS(=O)(=O)c1cccc(OCc2noc(-c3ccccc3)n2)c1 +CC(Oc1ccc(C(C)(C)C)cc1)C(=O)N1CCNC(=O)C1 +CCn1nc(CNc2nc(C)nc3onc(C)c23)c2ccccc21 +COc1ccc(C2CC(=O)c3cn[nH]c3C2)c(OC)c1OC +Cc1cccc(C)c1NC(=O)CSc1nc(-c2cccs2)n[nH]1 +CC(NC(=O)c1cnn(Cc2ccccc2)c1)c1nc2ccccc2[nH]1 +COc1ccccc1CNc1c(-c2ccccc2)c(=O)c1=O +CCc1noc(C)c1C(=O)NC(C)c1cccc(OC)c1 +CC1CCCN(C(=O)Nc2ccc(NC(=O)C3CC3)cc2)CC1 +COC(=O)c1cc(-c2csc(NC(=O)CC3CCCCC3)n2)c[nH]1 +CCOc1ccc2nc(C(=O)Nc3ccc4c(c3)OCCO4)cn2n1 +c1cc(NC2CC2)c2c(OCC3CCCO3)nccc2c1 +CCCNC(=O)c1c2c(nc3ccc(F)cc13)CCC2 +CC(NS(=O)(=O)c1cccs1)C(=O)N1CCOCC1 +CC(C)n1cnnc1C1CCCN(S(=O)(=O)CCCC#N)C1 +CC(=O)Nc1nc(C)c(S(=O)(=O)N2CCCC2)s1 +O=C(NCC(=O)N1CCC2(CC1)OCCO2)OCc1ccccc1 +Cc1cccnc1NC(=O)c1ccc(Oc2cccnc2)cc1 +O=C(COc1cccc(Cl)c1)Nc1ccon1 +CCc1nnc2n1CCN(C(=O)C1COc3c(cccc3OC)C1)C2 +O=C1CCCc2cc(NC(=O)c3cccc(-n4ccnn4)c3)ccc2N1 +CN(CC(=O)NCC1(c2ccc(F)cc2)CCC1)c1cnccn1 +COc1ccc(NC(=O)NCc2c(C)nn(C)c2C)cc1 +CCc1ccsc1C(=O)NCc1cnc(C)s1 +O=C(CSc1ncn[nH]1)Nc1ccc2c(c1)OCCO2 +O=C(NCCc1ccccn1)C1CCCN(C(=O)N2CCCC2)C1 +O=C(Nc1ccc(F)c(F)c1F)C1CC=CCC1 +COc1ccc(CCC(=O)NC2CCCCC2C)cc1N +CCNc1ncc(C(=O)NC2c3ccccc3CC2NC(C)=O)cn1 +CC(C)(CNC(=O)c1ccncc1F)c1cccc(F)c1 +Cc1cnn(CC2CCCN2CCS(=O)c2ccccc2)c1 +Cc1nc(-c2cccnc2)sc1C(=O)Nc1ccc(F)cc1F +O=C(C1CC1)N1CCN(CC(O)c2ccco2)CC1 +O=C(NCCNC(=O)c1ccccc1O)Nc1cccc(F)c1 +Cn1ccc(NC(=O)NCC(C)(O)c2ccc(F)cc2)n1 +CC1(C)CCCN(C(=O)c2cn(CC(N)=O)nn2)c2ccccc21 +O=C(Cn1ccc(=O)c2cccc(F)c21)NCC1CCCO1 +Cc1ccc(C(C)NC(=O)CS(=O)(=O)c2ccc(F)cc2)cc1C +CC(C)CCNC(=O)C(N)c1cc(F)cc(F)c1 +Cc1n[nH]cc1CNc1ncnc2cc(Cl)ccc12 +Cc1noc(C)c1S(=O)(=O)N1CCN(c2cc(C#N)ccn2)CC1 +Cc1cc(C(=O)OCc2nc(-c3cccs3)no2)c(C)n1C1CC1 +Cc1ccc(CNC(=O)Cc2ccc(-n3cccc3)cc2)cc1 +O=C(c1cc(-c2cccs2)[nH]n1)N1CCN(c2ccccc2)CC1 +CC(=O)Oc1cccc(C(=O)Nc2ccc3c(c2)OCO3)c1 +CC1COCCN1S(=O)(=O)c1ccc(N2CCOC2=O)cc1 +O=S(=O)(NCCc1n[nH]c(-c2ccco2)n1)c1ccccc1F +CCc1noc(CC)c1CNS(=O)(=O)c1ccc(F)cc1F +CN(C)C(=O)CCNC(=O)NCc1ccnc(OC2CCCC2)c1 +CCCn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2ncccc21 +COc1ccc(Br)c(CNC(=O)NC2CCCC2)c1 +Cc1csc(COC(=O)c2ccnc(-n3ccnc3)c2)n1 +Cc1ccccc1C(=O)NC(CC(C)C)C(=O)Nc1cc[nH]n1 +CC(NC(=O)COn1nnc2ccccc21)c1ccccc1 +FC(F)(F)c1cccc(OCCCCN2CCOCC2)c1 +C=C(C)CN(CC)C(=O)CNc1ccc(N2CCCC2=O)cc1 +Cc1cc(C)n(C(C)C(=O)NC(C)(C)c2cccc(F)c2)n1 +CCOC(=O)c1ccc(CN2CCCC(c3nccs3)C2)o1 +CC(=O)Nc1ccc(CNS(=O)(=O)c2ccc(C)s2)cc1 +Cc1csc(C(C)NC(=O)NCC(C)(C)c2ccncc2)n1 +CC(C)c1cc(-c2nn3c(C(C)C)nnc3s2)[nH]n1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc(N2CCCC2=O)cc1 +Cc1cc(-c2ccc(F)cc2)nc2cc(C(N)=O)nn12 +COC(=O)c1cc(C)nc(N(C)C)c1C(=O)OC +CCCn1nnnc1NC(=O)c1cc(Br)ccc1Cl +CC(NC(=O)NC1CCC(O)CC1)C(=O)N(C)C +O=C(c1ccco1)N1CCC2(CCC(=O)N2CC2CC2)CC1 +Cc1ccc(C(=O)NC(CN2CCOCC2)c2ccccc2)c(=O)[nH]1 +CC(O)CNC(=O)CNC(=O)c1cc2occc2n1C +Cc1nnc(Nc2cccc(Br)c2)[nH]c1=O +Cc1cncc(C2CCCN(C(=O)Cc3csc(C)n3)C2)n1 +N#Cc1ccccc1CN1CCN(C(=O)C2CCCC2)CC1 +CN1CCOC(CNC(=O)CCn2ccc3ccccc32)C1 +O=C(Nc1cccnc1)c1cc(=O)c(OCc2ccccc2F)co1 +COc1cn(S(=O)(=O)c2ccccc2)c2ccccc12 +CC(c1nc2c3ccccc3ncn2n1)n1cc(Br)cn1 +CCc1nnsc1C(=O)N1CCCC(n2cncn2)C1 +Cc1csc(CNc2ccc(C(=O)NC(C)C)cc2C)n1 +CCCn1nnnc1CSc1ncnc2nc[nH]c12 +CC(C)CCNC(=O)C1(C)CCC(=O)N1Cc1cccc(F)c1 +CCNc1ncc(C(=O)N2CCN(C(=O)c3cccs3)CC2)cn1 +CN(c1ccccc1)S(=O)(=O)c1c[nH]c2ncccc12 +CC1(c2ccccc2)CCC(=O)N(Cc2ccno2)C1 +CC(=O)Nc1cccc(OC(=O)Cc2cccc(F)c2F)c1 +COC(=O)c1cccc(C(=O)N2CCNC(=O)C2C)c1 +CN(CCO)C(=O)c1cn(Cc2ccccc2Cl)nn1 +O=C(Nc1ccc(F)cc1NC1CC1)C1CC2CCC1O2 +CC(C)NC(=O)N1CCC2(CC2C(=O)NCc2ccco2)C1 +O=C(Nc1ccc2cn[nH]c2c1)C1CC1c1ccco1 +Cc1cc(Cl)ccc1OC(C)C(=O)N(CCC#N)Cc1ccco1 +COCCNc1ncnc(NCc2ccc3c(c2)OCO3)c1N +Cc1cc(-n2nnc(C(=O)N3CCC(C(N)=O)CC3)c2C)ccc1F +N#Cc1nnn(Cc2ccccc2)c1C(F)(F)F +COc1ccccc1NS(=O)(=O)Cc1ccccc1Cl +Cc1ccc(NC(=O)CCN2C(=O)COc3ccccc32)c(C)c1 +COCC(=O)Nc1cnc(C)n1-c1nc(-c2ccc(F)cc2)cs1 +CNC(=O)NCC(=O)NCC1(c2cccc(Br)c2)CC1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cc(Cl)ccc3Cl)cc12 +Cc1cc(C(=O)NC(C)c2ccncc2)c(C)n1Cc1cccs1 +COc1ccc(CNc2ccc(F)cc2F)c(OC)c1 +CCc1ccc(CC2Oc3ccc(N)cc3N(C)C2=O)cc1 +CCCCn1nc(C(=O)NCCc2ccc(F)cc2)ccc1=O +N#Cc1cccc(C2NCCc3c(F)ccc(F)c32)c1 +COc1cc(C(=O)N2CCN(Cc3ccc(C)cc3)CC2)ccc1C +CCCN(C)C(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1C +Nc1c(C(=O)NCc2cccs2)nnn1-c1ccc(F)cc1 +Cc1ccc(NCc2cnn(-c3ccccc3)c2)cc1F +CCC(C)N(Cc1ccccc1)C(=O)CNC(=O)c1ccccc1 +CCNC(=O)c1ccc(CNC(=O)N(C)Cc2ccccn2)cc1 +CC(C)COC1CCN(S(=O)(=O)c2cccc(C#N)c2)CC1 +CS(=O)(=O)N1CCCN(C(=O)COc2ccc(Cl)cc2)CC1 +COC1(C)CC(NC(=O)c2n[nH]c3c2CCC3)C1(C)C +CCN(Cc1ccccc1Cl)C(=O)c1cc(C)no1 +COc1cccc2cc(C(=O)NCc3cccc(F)c3)oc12 +CC(=O)C(NC(=O)COc1ccc(Br)cc1F)C(C)C +Cc1nnnn1-c1cccc(C(=O)NCc2cccc(Cl)c2)c1 +COC(=O)N1CCC(NC(=O)c2ccc(F)cc2Cl)CC1 +COc1ccccc1-c1nnc(SC2CCCCC2=O)n1C +CCc1cccc(OC2CN(C(=O)CCc3ccncc3)C2)c1 +CCCCS(=O)(=O)NCc1csc(-c2ccccc2)n1 +CC(C)(C#N)N1CCN(C(=O)c2ccccc2Cl)CC1 +CN(C)C(=O)COCC1CC2OCCN(Cc3nccs3)C2C1 +CC(Oc1cccc(Cl)c1Cl)C(=O)OCC1CCC(=O)N1 +CCn1ccc(C(=O)Nc2nc(-c3ccc(C)cc3)cs2)n1 +CC(C)(C)NC(=O)Cc1csc(-c2ccc3c(c2)OCO3)n1 +COCCCNC(=O)CSc1ncccc1Cl +CN(Cc1cnc(N(C)C)nc1)C(=O)c1ccc(F)c(Cl)c1F +Clc1cccc(CN2CC3CCc4c[nH]nc4C3C2)c1 +Cc1nc(C)c(CNC(=O)N2CC(C)c3ccccc32)s1 +Cc1cccc(CS(=O)(=O)NCC(C)(O)c2ccccc2)c1 +Cn1cc(NC(=O)CC2CCOc3ccccc32)cc1C(N)=O +O=C(Nc1ccc2oc(=O)ccc2c1)c1ccn(-c2ccc(F)cc2)n1 +Cc1cc(NC(=O)c2nc(-c3ccco3)sc2C)ccn1 +CCCC(C)NC(=O)c1cc(S(N)(=O)=O)ccc1Br +CCc1cccc(OC(C(=O)N2CCNCC2)C(C)C)c1 +N#CCCC1CCCCN1S(=O)(=O)c1ccccc1 +COc1ccc(Cc2nnc(NC(=O)C(C)(C)C)s2)cc1OC +CC(C)(C(=O)Nc1ccc2c(c1)OCO2)c1ccc(N)cc1 +CCN(C1CCCC1)S(=O)(=O)c1ccc2c(c1)CCO2 +COC(=O)C1CC=CCC1C(=O)c1cn(C)c2ccccc12 +CC(CC(=O)NC(c1ccc(F)cc1)c1nccn1C)n1cccn1 +COc1cccc2c1CCNC2c1ccc2ncccc2c1 +CNc1ncc(C(=O)N(C)CCN(C)C(=O)OC(C)(C)C)s1 +C=C(C)COc1ccc(C(=O)N2CCCCC2)cc1 +COc1cc(NC(=O)c2cn3ccc(C)cc3n2)cc(OC)c1 +C=CCOc1cc(C(=O)NCCCO)cc2occc12 +C=CCCCN(C)C(=O)c1cc(Br)c[nH]1 +O=C(Nc1ccc(F)c(Cl)c1)N1CCN(Cc2ccncc2)CC1 +CC(C)c1nnc(CNC(=O)C(C)(C)c2cccs2)n1C +Cc1ccc(-c2csc(NC(=O)c3ccno3)n2)cc1 +C=CCNS(=O)(=O)c1ccc(OCC)c(NC(C)=O)c1 +Cc1ccn2ncc(C(=O)NCCNC(=O)CC(C)C)c2c1 +COc1ccc(C(=O)CCC(=O)Nc2ccccc2C)cc1 +COc1cccc(C(=O)NCC#CCOc2ccccc2C(N)=O)c1 +Nc1c(C(=O)Nc2ccc(F)c(F)c2F)oc2ccccc12 +CS(=O)(=O)N1CCC2(CCC(=O)N2Cc2cccnc2)CC1 +CCC(O)Cn1ncnc1CN(C)Cc1cccnc1 +O=C(Cc1ccsc1)NCc1ccc(C(=O)c2ccco2)s1 +CN(C)c1cc(C(=O)NCCOc2cccnc2)ccn1 +Cc1c(C(=O)OC2CCCCC2)sc2ncnc(NCCCO)c12 +Cc1ccncc1NC(=O)NCc1ccccc1OCCO +COc1ccc(NC(=O)CNc2cccc(Cl)c2)cc1OC +Cc1noc(C)c1C(C)NC(=O)Cc1csc(N2CCCC2=O)n1 +COc1cc(OC)nc(-c2cnn(CC(=O)Nc3cnn(C)n3)c2)n1 +N#Cc1c(-c2ccccc2)ncnc1N1CCCCC1 +CCN(Cc1ccncc1)C(=O)Nc1cccc(Cl)c1 +Cc1cccc(C)c1NC(=O)CCn1c(=O)cc(C)c2ccccc21 +COc1ccc(NC(=O)NCCOC(=O)Nc2ccccc2)cc1 +O=C(NCc1cccc(Oc2ccccn2)c1)c1cc(C2CC2)on1 +COc1ccc(F)cc1NC(=O)N1CCC(C)CC1 +CCNC(=O)NC1(C(=O)Nc2ccc(OC)c(F)c2)CCCC1 +CN(C)C(=O)C(C)(C)NS(=O)(=O)c1ccccc1-c1ccccc1 +COc1cc(CNC(=O)Oc2ccccc2)cc(OC)c1 +O=C(Nc1cccc(C(=O)N2CCCCC2)c1)C1CCCO1 +CC1CN(C(=O)c2ccccc2NC(=O)c2ccccc2)CC(C)O1 +O=C(NCC1CCCO1)NCC1COc2ccccc2O1 +COc1cc(CNC(=O)c2cc(C)n[nH]2)ccc1OCC(N)=O +Cc1ccc(Nc2ccc(NS(=O)(=O)c3cccs3)cc2)nn1 +Cc1occc1COC(=O)c1sccc1S(=O)(=O)N(C)C +CCc1oc(-c2ccc3c(c2)OCCCO3)cc1C#N +CC(C)CC(=O)N1CCN(C(=O)c2ccccc2F)CC1 +CC1=C(C(=O)Nc2ccc(F)cc2F)C(c2ccccc2)NC(=O)N1 +CCN(c1cccnc1)S(=O)(=O)CC1CCCCO1 +CC(=O)c1cc(C#N)c(N2CCN(c3ccccc3)CC2)nc1C +Cc1ccc(-n2cnc(=O)c3c[nH]nc32)cc1Cl +O=C(CC(c1ccc(F)cc1)n1cccc1)Nc1nccs1 +COC(=O)c1ccc(Nc2nccc3ccc(N)cc23)cc1 +COCCOCC(=O)NC1CCOc2c(Cl)cccc21 +O=C(Nc1ccc(Cl)c(F)c1)c1cccc(-n2cnnn2)c1 +CNc1nccnc1C1CCN(c2cc(C)ncn2)CC1 +CCn1ncc(C(=O)N2CCc3cc(F)ccc3C2)c1C(F)(F)F +CCOC(=O)C1CCCN(C(=O)C2(c3ccc(Cl)cc3)CC2)C1 +COc1ccc(Cn2c(CO)cnc2SC(C)C)cc1 +Cc1ccccc1CC(C)NC(=O)c1n[nH]c(=O)[nH]1 +Cc1cc(C)c(NC(=O)CN(C)C(=O)c2cc(F)ccc2F)c(C)c1 +O=c1[nH]cnc2c1nc1ccc(C(F)(F)F)cn12 +CC(C)C(NC(=O)NCc1ccccc1Cl)c1nnc2n1CCC2 +Cc1coc(-c2ccc(C)c(NC(=O)NC(C(N)=O)C(C)(C)C)c2)n1 +CCOc1ccc(CC(=O)Nc2cccc3cn[nH]c23)cc1 +CCc1cccc(OCCN2CCn3c(nn(C)c3=O)C2)c1 +Cc1c(NC(=O)N2CCC3(CC2)OCCO3)cccc1OC(F)F +CCCCNC(=O)Cn1ccn(-c2cccc(Cl)c2)c(=O)c1=O +CCOc1cccc(CNC(=O)Nc2cnccc2C)c1 +COCCN1CCC2CN(C(=O)C3CC=CC3)CC2C1=O +CCNc1nc2ccc(S(=O)(=O)CC(C)C)cc2s1 +COCCN1CCN(C(=O)c2cnn(C3CCCC3)c2C)CC1=O +CC(C)COc1cccc(CNC(=O)c2scnc2C2CC2)c1 +COc1ccc(-c2cc(N)n(-c3ccc(C)cc3)n2)cc1 +CNC(=O)CCC(=O)c1ccc2c(c1)OCCCO2 +CCCCCNC(=O)C(N)c1ccc(C)c(F)c1 +CC(=O)Nc1cc(NC(=O)C2CCN(C(C)=O)CC2)ccc1F +O=C(CNC(=O)c1ccc(Cl)cc1Cl)Nc1cccnc1 +CCOC(=O)N1CCC(NC(=O)Nc2ccc(C)c(Cl)c2)CC1 +CCCn1nnnc1CSc1nnc(-c2ccco2)n1N +COCCCN1CC2(CCN(c3nccs3)CC2)CC1=O +O=C(Cc1ccc(F)cc1)Nc1ccc(C(=O)N2CCCCC2)cc1 +Cc1c(F)cc(C(N)=O)cc1NC1CCC(C)CC1 +O=C(NCCC1CCCO1)c1ccc(Cl)cc1F +CC(C)(NC(=O)c1[nH]c2ccccc2c1Br)C(N)=O +CC(c1ccc(-n2cncn2)cc1)N(C)Cc1ccc(F)cc1F +Cc1nn(C)c2c(Nc3ccc4c(c3)CCC4)ncnc12 +N#Cc1cc(NCc2nc(C3CC3)no2)ccc1Cl +Cc1ccc(CN2CCC(c3nnc(Cc4ccccc4)o3)C2)cc1 +Cc1cnc(C)c(N2CCN(C(=O)c3cc(C(C)C)n[nH]3)CC2)n1 +Cc1n[nH]c(C)c1CNC(=O)c1cnc(C(C)(C)C)nc1 +CSc1ccccc1C(=O)N1CCN(c2c(C)n[nH]c2C)CC1 +CC1CCCCC1NC(=O)Cn1ncc2c([nH]c3ccccc32)c1=O +Cc1ccc(-c2cnn(C)c(=O)c2CC#N)c(C)c1 +O=C(NCCc1ccccn1)C1(c2ccc(F)cc2)CC1 +Cc1nc(C)c(CCC(=O)Nc2cc(F)ccc2F)c(=O)[nH]1 +O=C(NCc1cccc(F)c1)c1ccc(OCC2CCCO2)cc1 +Nc1cccc(Nc2ncnc3c2cnn3Cc2ccccc2)c1 +Cc1ncc(CNC(=O)Nc2ccccc2Oc2ccccc2)s1 +Cc1cccc(CCNC(=O)NC2CCN(c3cnn(C)c3)C2=O)c1 +O=C1CN(c2ncc(F)c(N3CCCC3)n2)CCCN1 +O=c1cc(-c2ccc(F)cc2)oc2cc(O)cc(O)c12 +CN(C)C(=O)Cn1cc(C(=O)N(C)Cc2cccc(F)c2)nn1 +COc1ccc2c(C)c(CCC(=O)Nc3nccs3)c(=O)oc2c1 +CCOC(=O)C1CCCN(C(=O)c2cccc(-n3cccc3)c2)C1 +CCn1nnc(C#N)c1-c1ccccc1Br +Cc1nn(C)c(C)c1CC(=O)N1CCOC(c2ccccc2Cl)C1 +CS(=O)(=O)Nc1ccc(-c2csc(-c3ccccn3)n2)cc1 +COc1ccccc1C(NC(=O)NC1CC1)c1ccccn1 +CC(C)(C)NC(=O)Cn1cccc1-c1nc(-c2ccc(F)cc2)no1 +CCC(=O)N(Cc1cc2ccccc2[nH]c1=O)c1ccc(C)cc1C +CCOCc1ccccc1CNC(C)C(=O)NC +O=C(Nc1nccs1)C1CCN(C(=O)NC2CCCCC2)CC1 +O=C(Nc1ccccc1N1CCC(CO)CC1)c1ccncc1Cl +COc1cc(=O)n(-c2ccc(C)cc2)nc1C(=O)Nc1cccc(C)c1 +COc1ccc(S(=O)(=O)Nc2nccs2)cc1 +CCNC(=O)Nc1ccccc1N1CCNC(=O)C1 +N#Cc1nc(NCCNC(=O)CC2CCCC2)ccc1Cl +CCC(NC(=O)CC1CCCC1)c1ccc2c(c1)OCCO2 +CC(c1cccnc1)N(C)C(=O)Nc1ccccc1Cl +Cn1cnnc1CCNC(=O)C1CCCCN1C(=O)OC(C)(C)C +Cc1cc(C)c(NC(=O)CNC(=O)c2cc(C)sc2C)c(C)c1 +CC1CCCC(C)N1C(=O)N(C)CC1CCOC1 +CC(Nc1ccc(-n2cncn2)c(F)c1)C1(C)CC1 +CCOC(=O)CN(C(=O)Cn1cccn1)C(C)C +Cc1ccnc2nc(C(=O)NC(C)CCc3ccccc3)nn12 +O=C(NCc1nc(-c2ccccc2)no1)c1ccsc1 +CC(C)Cn1nc(CC(=O)N=c2[nH]cc[nH]2)c2ccccc2c1=O +O=C(CN1CCOCC1)N1CCOCC(Cc2ccncn2)C1 +Cc1csc2cc(C(=O)N3CCc4ccccc43)cnc12 +CC(=O)NCCCOC(=O)C1CSc2ccccc2O1 +O=c1[nH]c(CNc2cccc(Cl)c2)nn1Cc1cccc(Cl)c1 +CCC(C)NC(=O)Nc1ccc(N2CCOCC2)cc1C(F)(F)F +CC(Cc1ccco1)NC(=O)c1cn(CC(=O)N(C)C)nn1 +COC(=O)c1cncc(N2CCC(CO)C(O)C2)n1 +OC(c1cnc2ccccc2c1)c1ccccc1F +COc1ncccc1CNC(=O)NCC(C(C)C)N1CCOCC1 +O=C(CCc1nc2ccccc2s1)N1CCCc2ccccc21 +Cc1cc(CN2CCN(C(=O)Cn3ccccc3=O)CC2)on1 +Cc1cc(NC(=O)c2nc3ccccc3s2)n(C(C)C)n1 +Cc1ccc(C)c(S(=O)(=O)CC(=O)NCC(=O)N2CCCC2)c1 +CNC(=O)CN1CCN(C(=O)Cc2ccc(OC)c(F)c2)CC1 +COC(C)(C)c1noc(CNC(=O)c2c[nH]c3ccccc3c2=O)n1 +O=C(C1=NC=CC1)c1cc2cc(Br)ccc2o1 +FC(F)(F)Oc1cccc(CN2CCOC(c3nccs3)C2)c1 +CCc1ncc(C(=O)N2CCC(C(=O)OC)c3ccccc32)s1 +CCC(CC)C(=O)NC(C#N)c1ccc(OC)cc1 +N#Cc1c(CCCNc2nc3ccccc3o2)n[nH]c1N +CC(C)C(NC(=O)c1c(F)cccc1F)C(=O)N1CCOCC1 +Cc1ccc(-c2n[nH]c(NC(=O)c3cnc4ccccn4c3=O)n2)cc1 +CCc1ncc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)s1 +CC1CCCC2CCCN(S(=O)(=O)c3cc(C(N)=O)n(C)c3)C12 +CCOC(=O)CCC(=O)Nc1nnc(CC)s1 +Cc1noc(C)c1C(=O)NCc1ccc(NC(=O)C(C)C)cc1 +CCc1ncc(C2N(C)C(=O)c3ccccc3N2CC(=O)NC)s1 +CC(=O)Nc1cc(C(=O)OCc2ccc(F)cc2)ccc1F +Cc1ccc(C)c(NC(=O)c2cc3c(nc2N)CCC3)c1 +Nc1ccc(NC(=O)c2ccc3c(c2)OCO3)c(Cl)c1 +Cc1cccc(OCC(C)NC(=O)Cn2ccc(=O)[nH]c2=O)c1 +N#CC1(NC(=O)CSc2nnnn2-c2ccccc2)CCCC1 +O=C1CCCN1C1CN(C(=O)Cc2ccsc2)C2CCCOC12 +Cc1c(CNC(=O)Nc2cc(Br)ccc2F)cnn1C +CC(=O)Nc1cc(C(=O)NCC(=O)NC(C)(C)C)ccc1F +CC1COCC(C)N1CC(=O)NCc1ccc(Cl)cc1 +CNC(=O)CN1CCN(C(=O)Nc2ccc(Cl)cc2Cl)CC1 +CC(NC(=O)CNC(=O)c1ccsc1)c1ccc(F)cc1Cl +COc1ccc(Cl)cc1CNC(=O)CSc1n[nH]c(N)n1 +Cc1cccc(Cn2cc(NC(=O)c3ccoc3C)cn2)c1 +COCCS(=O)(=O)NCc1ccc(-n2cccn2)cc1 +Cn1ccnc1SCC(=O)Nc1ccc(Cl)c(Cl)c1 +O=C(CSc1ccncc1)Nc1cc(-n2cccn2)ncn1 +Cc1oc(-c2ccccc2)nc1C(=O)NCC(C)N1CCOCC1 +CC(=O)N1CC(C(=O)NCCC(C)C)Oc2ccccc21 +COc1cccc(OCc2nn3c(C#N)c(C(C)C)nc3s2)c1 +Nc1ccc(C(Cc2ccccc2)C(=O)N2CCCC2)cc1 +COC(=O)c1nn(C)c(N)c1-c1ccc(C)cc1C +O=C1COc2ccc(C(=O)CCC(=O)N3CCNCC3)cc2N1 +CCNC(=O)NC1CCC(OC(=O)c2c(C)oc(C)c2C)CC1 +CC1(C)CC(NC(=O)c2cccc(-n3cnnn3)c2)CCO1 +CCC(C)(C)NC(=O)Cn1nc(C)c(Br)c1C +CN(CC(=O)NCCn1ccnn1)c1ccccc1 +CC(Sc1nnc(-c2ccco2)n1C)C(=O)Nc1nccs1 +Cc1cccc(CN2CCc3[nH]nc(C4CC4)c3C2)n1 +O=C(Nc1ccc(-c2cn3c(n2)SCC3)cc1)c1ccc(F)cc1 +COC(=O)CC(c1cccc(OC)c1)c1c(O)n[nH]c1C +CSc1ncnc2c1ncn2CCC(=O)OC(C)(C)C +O=C(NCc1ccco1)c1cccnc1-c1nc2ccccc2s1 +CC(C)n1ncc2c(-c3ccsc3)c3sc(=O)n(C)c3nc21 +Cc1nc(CC(=O)Nc2nc(-c3ccccc3)cs2)cs1 +CCc1ccc(C(=O)Nc2sc(-c3ccccc3)cc2C(N)=O)o1 +Cc1ccc(-c2nnn(-c3ccccc3C)c2N)cc1 +Cc1cc(C)nc(N2CCN(CCC(=O)NC3CCCCC3)CC2)n1 +CCOC(CC)C(=O)NCC1(c2ccc(Cl)cc2)CCOCC1 +CCCc1cc(C(=O)N(C)CC2CC(=O)N(C(C)(C)C)C2)n(C)n1 +CCOc1cc2c(cc1NC(=O)NCC(O)c1ccco1)OC(C)C2 +O=C(NC(Cn1cccn1)c1ccccc1)c1ccc2nccnc2c1 +Nc1ccc2c(c1)N(Cc1ccc(Cl)cc1)CCS2 +Cc1cc(C)n(-c2ccc(SC(C)C#N)nn2)n1 +CCCc1n[nH]cc1C(=O)N1CCN(C(C)C)C(CC)C1 +CN(C)c1cccc(C(=O)Nc2nc(-c3ccccn3)cs2)c1 +Cc1ccc(NC(=O)C2CCOCC2)cc1Cl +N#Cc1ccc(-c2noc(COc3ccccc3Cl)n2)nc1 +COc1cccc(OCCc2nc3c(s2)CCN3)c1 +Cc1nnnn1-c1cccc(NC(=O)c2ccccn2)c1 +CCn1cc(NC(=O)c2ccccc2Cl)c(C(N)=O)n1 +Cn1cc(Br)c(C(=O)Nc2ccccc2C(N)=O)n1 +Cc1ccc(CCNC(=O)c2ccccc2OCC(N)=O)c(C)c1 +COc1ccccc1NC(=O)CC(C)n1ccc(C)n1 +Cc1cn2cc(C(=O)NC3COC4(CCCC4)C3)ccc2n1 +O=C1CCC(C(=O)NC(c2ccc(Cl)cc2)c2ccsc2)CN1 +Cc1ccc2cc(CNCCc3ccccc3)c3nnnn3c2c1 +CCn1cc(S(=O)(=O)Nc2ccc(C)c3ncccc23)c(C)n1 +CN1CC2(CCN(C(=O)C3(c4ccccc4)CCCC3)CC2)OC1=O +O=C(Nc1ccc2c(c1)COC2)c1ccc(CN2CCCC2=O)cc1 +O=C1CC(C(=O)N2CCC(c3cc(=O)[nH]cn3)CC2)C2(CCCC2)O1 +Cc1cc(=O)n(CC(=O)Nc2cccc(Cl)c2C)nc1C +COc1ccc(Cl)cc1NC(=O)CNc1ccc(C(N)=O)cc1 +CCNC(=O)c1cc(NC(=O)c2ccc(C#N)cn2)nc2ccccc12 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(-n2cccn2)cc1 +Cc1noc(C2CCCN(Cc3c(C)nc4sc(C)cn34)C2)n1 +O=C(Cn1ncc2ccccc2c1=O)NCC1(c2ccccc2)CC1 +Cc1ocnc1CNC(=O)Nc1ccn(CC(F)F)n1 +Cc1ccc(CNC(=O)c2ccccc2S(C)(=O)=O)c(C)c1 +Cc1nn(C)c2nc(NCCc3nccs3)sc12 +Cc1ccc(C(=O)NCCNC(=O)N(C)C(C)C)cc1 +CC1Cc2cc(C(=O)OCCO)ccc2N1S(C)(=O)=O +O=C(Cc1ccccc1F)Nc1ccc(NC(=O)c2ccco2)cc1 +CCCNS(=O)(=O)c1ccc(OC)c(C(=O)N2CCCCC2)c1 +CCCOc1ccc(-c2cc(CO)c(=O)n(CCC)n2)cc1 +O=C(CC1(O)CCCCC1)NCC1(C(O)c2ccccc2)CC1 +O=C(C1CC=CC1)N1CCN(c2ncccn2)CC1 +CCCN(CCC)C(=O)c1csc(-c2cnccn2)n1 +Cc1ccc(NC(=O)CNc2ccc(C(N)=O)cc2)cc1 +CCCCn1c(SCC(=O)Nc2ccc(C)c(C)c2)n[nH]c1=O +Cc1nc(SCC(=O)NCC(F)(F)F)c2c(C)c(C)sc2n1 +Cc1cc(CN(C)C(=O)c2ccc(Oc3ccccc3)cc2)no1 +N#Cc1cccnc1NCCCn1nc2n(c1=O)CCCC2 +O=C(OCC1CC(=O)N(C2CC2)C1)C1CC1c1cccc(Cl)c1 +Cc1cc(=O)c2c(C#N)cn(C3CCCCC3)c2[nH]1 +O=C(CCCC(=O)c1ccc(F)cc1)NCc1ccccn1 +Cc1ccc(NC(=O)CSc2ccccc2O)cc1 +C=CCNC(=O)c1nnn(Cc2ccc(C)cc2)c1OC +Cc1ccc(C(=O)N2CCc3cc(N)ccc32)c(O)c1 +CCNC(=O)C(C)NC(=O)COc1ccc(C)cc1C +COc1ncnc2c1CCN(C(=O)C1CCOC1)CC2 +CN(C)C(=O)c1ccc(N2CCCC(C(N)=O)C2)cc1 +Cc1cccc(CNC(=O)c2cccc(OCC(F)F)n2)n1 +Cc1cccc(OCC(=O)Nc2ccnc(C)c2)c1 +N#Cc1cccc(CNC(=O)Nc2ccc(F)c(Cl)c2)c1 +Cn1cc(C(=O)N2CCCC(c3nnc4n3CCCCC4)C2)cn1 +COc1cc(CNC(=O)COc2ccc(Cl)cc2Cl)ccn1 +Cc1ccc(Br)cc1NC(=O)N1CCNC(=O)C1 +N#CC(C(=O)c1ccc2c(c1)NC(=O)CO2)c1nc2ccccc2[nH]1 +Cc1ccc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)cc1Cl +COC(=O)c1ccc(Cc2nc3sc4c(c3c(=O)[nH]2)CCCC4)o1 +CC(NC(=O)NCC(=O)NC1CC1)c1ccc(OC(F)F)cc1 +CC1(C(=O)NCCOCC(N)=O)CCCCCC1 +Nc1cc(F)cc2c1CCNC2Cc1cc(F)cc(F)c1 +Cc1cccc(CNc2ccc(C(=O)N3CCOCC3)c(Cl)c2)c1 +Cc1nc(C)c(CNS(=O)(=O)c2c(C)noc2C)s1 +Cc1nc(NCCCO)cc(-c2cncc(-c3ccccc3)c2)n1 +C#CCOc1ccc(C(=O)NCC(O)c2cccc(F)c2)cc1 +CC(=O)Nc1cccc(OCCNC(=O)NCc2ccc(C)s2)c1 +Cc1cc(C)n(Cc2cccc(C(=O)Nc3n[nH]c(C(C)C)n3)c2)n1 +COc1cc(OC)cc(C(=O)NCC(=O)Nc2nc(C)c(C)s2)c1 +COc1cc(C(=O)Nc2ccnn2C(C)(C)C)ccc1Cl +CSc1ccc(NC(=O)C2CN(C(=O)c3cnccn3)C2)cc1 +Cc1nc(N2CCCC(C)C2)c2c(C)c(C)sc2n1 +COCc1nc2ccccc2n1CC(=O)Nc1ccccc1C +CCOCCC(=O)Nc1cc(C)nc(C(C)C)n1 +Cc1cc(=O)[nH]c(NCCNC(=O)c2cn(-c3ccccc3)nn2)n1 +Cc1cc(C(=O)Nc2cccc(-c3nnnn3C)c2)sc1C +O=C(NCCCc1ccc(Cl)cc1)C1CC2CCC1O2 +COC(=O)Cc1cn2nc(-c3cccs3)cc2[nH]1 +CN1CCN(C2CCN(c3nc4ccccc4o3)CC2)C1=O +CC(C)NS(=O)(=O)c1ccc(NCc2cn[nH]c2)cc1 +COc1ccccc1-c1cccc(C(=O)NCc2cnc(C)cn2)c1 +Cn1c(=O)c2c(ncn2CCOC(=O)CC2CCCC2)n(C)c1=O +Cc1ccc(CN(C)C(=O)CCC(=O)c2ccccc2)o1 +Cc1ccc(-c2nc(C(=O)NC(C)(C)C)cs2)n1C +COc1ccc(-c2nc(Cn3nccc3-c3ccncc3)co2)cc1 +Cc1cccc(-c2cc(=O)[nH]c(-c3ccncc3)n2)c1 +CC(CNC(=O)C(O)c1cc(Cl)cc(Cl)c1)Cn1cccn1 +C#CCN1CCN(C(=O)NCc2cscn2)CC1 +O=C(c1cc[nH]n1)N1CCN(CCCc2ccccc2)C(CCO)C1 +CN(C(=O)COc1ccc2c(c1)OCO2)C1CCCCC1 +O=C(Nc1ccc(F)cc1OCC1CC1)c1cn2cccnc2n1 +O=C(NCCOc1ccccc1)C1CC(=O)N(CC(F)(F)F)C1 +Cc1n[nH]c(C(NC(=O)c2ccc(Br)cc2)C(C)C)n1 +Cc1c(C(=O)N2CCC(C)CC2)cnn1-c1ccc(Cl)cc1 +Cc1cc(Br)cc2cc(C(=O)NCCNC(N)=O)oc12 +CCCc1nn2cc(-c3cccc(OC)c3)nc2s1 +CCNC(=O)NC1(C(=O)NCC2CCCC(C)C2)CCCC1 +O=S(=O)(c1ccccc1)N1CCN(Cc2ccc(F)cc2)CC1 +CN(C)c1ccc2[nH]c(=O)cc(C(F)(F)F)c2c1 +COCCCC1CCCCN1C(=O)c1csc(C)c1 +CCCCS(=O)(=O)N1CCC2(CC(=O)c3ccccc3O2)C1 +CC(NS(=O)(=O)c1ccc(N)nc1)C1CCCO1 +CCOc1ccc(F)c(C(=O)NCc2ccc(OC)cc2)c1F +CC(=O)Nc1ccc2c(c1)N(C(=O)c1cccs1)CCC2 +CN1CCC(NC(=O)N(Cc2ccccc2F)C2CCC2)C1=O +Cc1ocnc1CNS(=O)(=O)c1ccc(F)cc1Br +Cc1ccc(C(=O)NCC(=O)Nc2ccc(F)c(F)c2)o1 +Cn1cc(C(=O)NCCNC(=O)c2cccnc2)c(C(C)(C)C)n1 +CCNC(=O)c1cc(S(=O)(=O)NCC)ccc1C +Cc1noc(C)c1CSc1ccc(Br)cn1 +CCC(=O)NCC(O)c1ccc(OC)c(OC)c1 +COC(CNS(=O)(=O)c1cc(C(N)=O)n(C)c1)c1ccccc1 +Cc1nn(C(C)C)c(C)c1NC(C)c1ccncc1 +Cc1csc(-c2cc3ccc(O)cc3oc2=O)n1 +CC(=O)c1ccc(NC(=O)Cc2nc(-c3ccco3)oc2C)cc1C +COc1ccc(F)c(NC(=O)Cc2cccc3cccnc23)c1 +O=S(=O)(N1CCCCCC1)N(CCc1cccc(F)c1)C1CC1 +CSc1nc(C)cc(C(=O)N(C)Cc2ccccc2F)n1 +Cc1c(C(=O)Nc2nccs2)oc2ccc(Cl)cc12 +COCCN1CCC2(CN(C(=O)c3ccsc3)CC2C)C1=O +O=C(c1ccnc(-c2ccc(C3CCCC3)cc2)c1)N1CCOCC1 +O=C(c1nccc2ccccc12)N1CCCCC1Cn1cccn1 +O=C(NCCNS(=O)(=O)c1ccccc1)C1CC1 +N#CCCNS(=O)(=O)c1ccc(C(=O)Nc2cccnc2)cc1 +COc1ccc(CN(C)C(=O)Nc2nnc(C3CC3)s2)cc1 +COC(=O)CCNC(=O)c1cc(N)c(F)cc1Br +CC(C)n1cnc2cc(COC(=O)C3CCCN3)ccc21 +CC(=O)NC(CC(=O)N(C)Cc1cccnc1)c1cccs1 +CC(=O)Nc1nc(CSc2nc3c(cc2C#N)CCCC3)cs1 +CC(C)COC1CCN(C(=O)NCc2ccc(C#N)cc2F)C1 +CC(C)c1cc(C(=O)OCC#Cc2ccccc2)n[nH]1 +O=C(NCCCc1ccccc1)N1C2CCC1COC2 +CC(O)(CNC(=O)c1c(F)cccc1F)C1CC1 +COc1ccc(Cl)cc1NC(=O)Oc1ccc2c(c1)ncn2C +Cc1ccc(OCCC(=O)NC(C)(C)C#N)c(C)c1 +CCCc1nnc2sc(C=Cc3ccccc3OC)nn12 +CC(=O)c1ccccc1NS(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1nn(C)c(C)c1C(=O)Nc1cnn(C(C)(C)C)c1 +CCC1(C)CCN(C(=O)Cc2ccccc2N)CC1 +COC(=O)C(C)CNC(=O)Nc1ccc(C(C)=O)c(C)c1 +Cc1ccc(N2CCCC(N(C)Cc3cnn(C)c3)C2)nn1 +Cc1ccc(-c2csc3ncnc(NC(C)(CO)CO)c23)cc1 +O=C(CCc1ccc2c(c1)OCO2)N1CCCCC1 +CC(NCC(O)c1ccccc1F)c1ccc(-n2ccnc2)cc1 +CCC(C)(C)NS(=O)(=O)c1ccc2c(c1)CCN2 +CCCCCC(C)NC(=O)Cn1cnc2sc(C)cc2c1=O +Cc1cc(NC(=O)c2ccccc2OC(C)C)no1 +O=C(CC1CCCC1)NCc1ncc(-c2ccccc2)[nH]1 +Cc1ccc(CC(=O)Nc2ccn(Cc3ccccn3)n2)s1 +CCC(C)C(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +CC(C)CCNC(=O)CCC(=O)c1ccc(F)c(N)c1 +CC(C)n1cc(C(=O)N=c2[nH]c3ccccc3[nH]2)c2ccccc2c1=O +CCc1ccc(NC(=O)CC(C)n2ccnc2)cc1 +Cc1ccccc1OCCNc1ncnc2[nH]cnc12 +COc1cccc(C(C)NCCN2CCOCC2)c1 +CC(C)N(C)c1cccc(NC(=O)NC2CCC3(CC2)OCCO3)c1 +Cc1nnc(COc2ccc(NC(=O)CCC3CCCCC3)cc2)o1 +COc1ccc(CC(=O)Nc2cnn(C)c2)cc1F +NS(=O)(=O)N1CCC(C(=O)NCc2cccnc2)CC1 +N#Cc1ccc(CNCCc2nnc3ccccn23)cc1 +O=C(NCc1cccc(Cl)c1)Nc1ccc(-n2cnnn2)cc1 +COc1ccc(N(C)Cc2ccccc2)n2nc(N)nc12 +CC(Cc1ccccc1F)C(=O)Nc1ccc(-n2cncn2)cc1 +O=C1CC(C(=O)n2cnc3ccccc32)CN1c1ccccc1 +C#CCN1CCN(C(=O)NCCCOc2ccc(OC)cc2)CC1 +COC(=O)C1=C(C)C(C(=O)OCC2CCCO2)=NC1C +Cc1c(C(C)NC(=O)N2CC(C)OC(C)C2)cnn1C +CCC(=O)Oc1ccc(C(=O)NCC2CCCO2)cc1 +CC(Cc1cnccn1)N(C)Cc1cc(F)cc(F)c1 +Cc1ccc(C(=O)N2CC=C(c3c[nH]c4ncccc34)CC2)cn1 +CCOC(=O)c1c(C)oc2nc(CSc3ccccc3)nc(N)c12 +CC1CCCCN1C(=O)c1cc(Br)ccc1N +O=C(CCC(=O)N1CCC(Oc2ccccc2)CC1)c1cccs1 +Cc1ccccc1NC(=O)c1cnc(N2CCOCC2)c2ccccc12 +OCCCc1c[nH]c2cc(Br)ccc12 +CCCCNC(=O)C(C)Sc1nncn1-c1ccccc1C +O=C(Nn1cnc2ccccc2c1=O)C1CCN(C(=O)C2CC2)CC1 +COCC(=O)N1CCOCC2(CCC(Cn3ncccc3=O)O2)C1 +CCOc1ccc(-c2c[nH]c(N)c2C#N)cc1Cl +CNC(=O)N1CCCC(c2cccc(C(=O)NCCCOC)c2)C1 +O=S(=O)(NCC(F)F)c1cc(Cl)cc2c1OCC2 +CCn1cc(C(=O)NCC(C)(C)c2cccc(C)c2)cn1 +Cc1nc2ccccc2c(=O)n1NC(=O)c1ccccc1Cl +CCNC(=O)COc1ccc(NC(=O)c2cc(C)no2)cc1 +CCN1C(=O)COc2cc(Br)ccc21 +COc1ccc2nc(C)n(-c3ccc4c(c3)OCO4)c(=O)c2c1 +Cc1nc(-c2ccccn2)sc1C(=O)N(C)Cc1cccnc1 +COCCNC(=O)c1cc2cnn(C(C)C)c2nc1N +CCC(=O)NC1CCCN(C(=O)CCC(C)(C)C)C1 +CC(C)(C)Cc1nnc(C2CCCN(C(=O)c3ccccc3F)C2)o1 +FC(F)(F)c1nc2nccc(-c3ccco3)n2n1 +CC(C)N(C(=O)C1CC(=O)N(Cc2ccccn2)C1)C1CCOCC1 +COc1ccc2c(c1)nc(C#N)n2Cc1cccnc1 +CCNc1ccc(S(=O)(=O)N2CCOC(C)C2)cc1 +CN(C)c1cccc(C(=O)N2CCC(C(N)=O)CC2)c1 +CC1CN(C(=O)CSc2nc3ccccc3[nH]2)CCO1 +Cc1oc2ncn(Cc3ccccc3Cl)c(=O)c2c1C +O=C(NCC(=O)N1CCOc2ccccc2C1)c1cc2ccccc2[nH]1 +O=C(OCC1CCCO1)c1ccc(OCC2CC2)cc1 +Cc1cc(C2CCCN2C(=O)c2cc(-c3ccc(F)cc3)on2)no1 +CNC(=O)c1cn[nH]c1C1(C)CCCN(C(=O)c2cnccn2)C1 +CC(=O)Nc1nonc1-c1nnc(SCc2ccc(C)cc2)n1C +CCN(CC(C)C#N)C(=O)CNc1cc(Cl)ccc1SC +CCOc1ccc(CNS(=O)(=O)Cc2cccc(C)c2)cc1 +Cc1nn(CC(C)C)c(C)c1S(=O)(=O)N(C)Cc1cccn1C +N#Cc1cnc(NCCNc2nnnn2-c2ccccc2)c(Cl)c1 +COC(=O)c1ccc(NC(=O)c2ccccc2OC)s1 +Cc1ccc(CNC(=O)c2csc(NC(=O)CC(C)C)n2)o1 +COc1ccc(F)c(NC(=O)N2CCOC(C)C2C)c1 +Cn1c(C(=O)NC(C)(C)C)nnc1-c1ccccn1 +CN(Cc1c(F)cccc1Cl)C(=O)COc1ccc(C#N)cc1 +O=c1cc(-c2ccccc2)[nH]c2c(Cl)cccc12 +CN1C(=O)C(C)(C)c2cc(C(O)Cc3cccs3)ccc21 +CC(C)CC(C(=O)N(C)CCc1ccccn1)N1CCCCC1=O +O=C(c1cccnc1)N(Cc1ccccn1)c1ccc(F)cc1 +c1cc(N2CCOCC2)nnc1N1CCOCC1 +CCCOc1ccc(C(=O)Nc2ccccn2)cc1 +O=C(c1ccc2nccnc2c1)N1Cc2cncnc2C1 +CCC(CC)NC(=O)NCC(C)(C)N1CCOCC1 +CCN(CC)C(=O)N1CCC(C(=O)OCc2nc(C)no2)CC1 +Cc1ccc(F)c(NC(=O)COc2ccccc2F)c1 +Cc1ccc(NCC(=O)Nc2nnc(C(C)C)s2)cc1C +COCc1cn(CC2CCN(C(=O)NC3CCCCC3)CC2)nn1 +CC(C)Oc1cccc(C(C)NC(=O)c2cn3cccnc3n2)c1 +CC(C)(C)N1CC(C(=O)NC2(Cc3ccc(Cl)cc3)CC2)CC1=O +Cc1nccc(CNC(C)c2ccc(NC(N)=O)cc2)n1 +CC(=O)c1ccc(C#CCNC(=O)c2cc3ccccc3o2)cc1 +COc1ccc(C(=O)Nc2cccc(C(C)=O)c2)c(N)c1 +CCc1nc(CC(=O)Nc2cccc(C(=O)NC3CC3)c2)cs1 +COCCCNC(=O)c1cccc(NC(=O)Nc2ccccc2)c1 +Cc1ccc(-c2noc(C3CCN(C(=O)CC(C)C)CC3)n2)nn1 +CCC(C)(C)NC(=O)c1ccc(NC(=O)NCC(C)C)cc1 +Cc1sc(NC(=O)c2cccs2)c(CN2CCOCC2)c1C +CCN(CC1CCOC1)C(=O)Cn1nnc2ccccc2c1=O +COc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 +CC(=O)c1cccc(NC(=O)CNC(=O)c2cccs2)c1 +CN(C)c1nc2cc(NC(=O)Cc3cccs3)ccc2o1 +Cc1ccc2cccc(C(=O)NCC(=O)Nc3ccc(F)cc3)c2n1 +CCCCNC(=O)C1CCC(C)N(C(=O)c2ccc(C)cc2)C1 +CCOC(=O)c1cnc(N2CCCCC2)nc1C(F)(F)F +COc1ccc(CNC(=O)COc2ccc(OC)cc2)cc1 +COc1c(Br)cccc1CCNC(=O)c1cc[nH]n1 +COc1ccc(NC(=O)c2ccc(Cl)cc2N)cc1 +Cc1cc(=O)c(OCC(=O)NCCC(C)C)cn1C +CC(=O)N1CCN(C(=O)c2cnn(C)c2C)CC1 +Cc1cc(NCc2cn3nc(C)sc3n2)nc(-c2cccnc2)n1 +O=C(NC(c1ccncc1)c1ccc(F)cc1)C1COc2ccccc21 +CC(C)C(=O)N1CCCC(c2csc(Nc3cnccn3)n2)C1 +CC(C)CC(=O)Nc1ccc(Oc2cccc(C(N)=O)c2)nc1 +CCCCc1ccc(N2CC(C(=O)OCC)CC2=O)cc1 +CC(C)c1nccn1Cc1cccc(NC(=O)N(C)C(C)CC#N)c1 +Cc1cccc2c1cnn2CCC(=O)NC(C)c1ccccc1 +O=c1c(NCc2ccco2)c(-c2ccc3c(c2)CCCC3)c1=O +Cc1ccc(CN(C)C(=O)c2ccc(Cl)c(Cl)c2)o1 +Cc1cc(-c2nnc3sc(C(C)C)nn23)ccc1N +O=C(Cc1ccon1)N=c1[nH]c2ccccc2n1-c1ccccc1 +Cc1ccc(CNC(=O)C(C)OCc2ccccc2)cn1 +Cc1ccc2cccc(OCC(O)COCc3ccco3)c2n1 +NC(=O)c1c(NC(=O)COc2ccc(F)cc2)sc2c1CCCC2 +Cc1cc(C(=O)N2CCN(Cc3cscn3)CC2)c(C)o1 +Oc1ccc2c(c1F)C(CC1=CCCCC1)NCC2 +CCc1cccc(OCC(=O)Nc2ccccc2N)c1 +CCCC1CN(C(=O)CNC(=O)c2ccc(C#N)cc2)CCO1 +CC(=O)c1cccc(NC(=O)C2=C3C(=O)N=CN=C3OC2C)c1 +CCCCn1nc(Cn2cncn2)nc1CN1CCCC1=O +CCN(CCC(F)(F)F)C(=O)Nc1ccc(N2CCCC2=O)cc1 +Cc1cccc(NC(=O)c2cccnc2N2CCOCC2)c1C +Cc1cnc(CCNC(=O)NCCc2ccc(F)cc2C)s1 +CCc1nnc2n1CCN(C(=O)c1cnc3snc(C)c3c1)C2 +[H]N=c1n(CC=C)c2ccccc2n1CC(=O)c1ccc(OC)cc1 +Cn1cc(C(=O)CSc2ncnc3c2cnn3C)cn1 +NC(=O)C(Cc1cccc(N)c1)c1ccc(F)cc1 +O=C(CCc1cccnc1)N1CCCN(c2ncccn2)CC1 +Cc1ccc(NC(=O)c2c(C)nn3ccccc23)cc1 +O=C(Nc1nccs1)NC1CCN(c2ccccc2)C1=O +CCCc1cc(=O)n2nc(-c3cccc(F)c3)cc2[nH]1 +CCc1nnc(CSc2ncnc3sc(C)cc23)o1 +CC(C)OCCCNC(=O)Nc1cccc(Br)c1 +CCCCNC(=O)Cn1cc(CO)c2ccccc21 +NC(=O)c1ccc(NC(=O)C2CC3CCC2O3)cc1F +Cc1cc(NC(=O)c2cccn(Cc3ccccc3)c2=O)no1 +CC1CCCCN1C(=O)c1ccc(-n2ccnc2)cc1 +COCCNC(=O)CNC(=O)Cn1ccc2ccc(Cl)cc21 +CCCn1nc(C)c(CN2CC(C)OC(CC)C2)c1C +CN(C(=O)c1ccc(F)c(F)c1F)C(C#N)c1ccccn1 +COc1ccnc(NC(=O)c2cncc(-c3ccc(N(C)C)cc3)c2)c1 +CC1CN(S(=O)(=O)CCNC(=O)C2CCCC2)CC(C)O1 +CC(=O)N1CCCC1C(=O)N1CCN(c2ccc(Cl)cc2)CC1 +COc1cccc(N(CC(=O)N2CCCCC2)S(C)(=O)=O)c1 +Cc1ccc(C)c(C(=O)N2CCC(C(=O)Nc3nncs3)CC2)c1 +COCCOc1cccc(C(=O)Nc2nc(-c3ccco3)cs2)c1 +COc1ccccc1NC(=O)c1cccc2c1NC(=O)C2 +CN1CC(C(=O)NCc2cccc(OCc3ccccc3)c2)CC1=O +Cc1nc(CNC(=O)CCc2nc[nH]n2)c(C)s1 +O=C(NCCCc1ccc(Cl)cc1)NCc1nnnn1C1CC1 +CN(C)c1cccc(C(=O)OCc2nnc(-c3ccccc3)o2)c1 +C#CCCSc1nncn1-c1cccc(NC(C)=O)c1 +Cc1ccc(C)c(C(=O)NCC(C)(O)c2ccc3c(c2)OCO3)c1 +Cc1ccc(C(O)CCNc2ccccc2C)cc1N +Cc1ccc(N(C)C(=O)Cn2cnc3onc(C)c3c2=O)cc1C +Cc1cnc(C(=O)N(CC2CCC2)C(C)c2ccccc2)cn1 +CCOC(=O)CC1NCCc2cc3cc[nH]c3cc21 +O=C(OCc1nnnn1-c1ccccc1)C1(c2ccccc2)CCC1 +CC(c1ccccn1)N(C)C(=O)NCc1ccnc(OC2CCC2)c1 +CC(=O)Nc1cccc(NC(=O)COc2ccc(F)c(Cl)c2)c1 +CCc1noc(CC)c1CNC(=O)c1ccnc(C(=O)OC)c1 +CCc1nc(CNc2cccc(NC(=O)c3ccccc3)c2C)no1 +Cc1nnc2n1CC(NC(=O)C1CC(=O)N(Cc3ccco3)C1)CC2 +CCN(C(=O)Cn1nc(C)nc1C)c1cccc2ccccc12 +CCN(CCNC(=O)c1ccc(=O)n(C)c1)c1cccc(C)c1 +CCOC(=O)CSc1nc2ccc(NC(C)=O)cc2s1 +O=C(COC(=O)c1ccc(F)cc1)Nc1ccc(Cl)cn1 +COc1cccc(-c2nnn(Cc3ccc(SC)c(OC)c3)n2)c1 +COc1ccc(NC(=O)c2cnns2)c2cccnc12 +CCc1ccccc1NC(=O)C(C)NC(=O)c1ccco1 +CCN1CC2(CC1=O)CN(C(=O)C(C)C)CCN(S(C)(=O)=O)C2 +CCOCc1ccccc1CNC(=O)N1CCCC1(C)C +COc1ccc(Nc2nccc3c2nnn3C)cc1 +CCN(CC)C(=O)Nc1ccccc1SCC(C)C#N +Cc1cc(CN(C)C(=O)C(C)NC(=O)c2ccc(Cl)cc2)no1 +CC(C)C(=O)N1CCC(NC(=O)c2cccc(C#N)c2)CC1 +Cc1ccc(CC2C(=O)Nc3c(C)cccc32)s1 +CCCS(=O)(=O)N1CCCC1c1ccc2c(c1)OCCO2 +Cc1noc(C)c1C(=O)N1CC(CO)CC(CN2CCOCC2)C1 +O=C1Cc2cc(C(=O)CSc3nnc4c(n3)CCCC4)ccc2N1 +CNC(=O)c1ccc(C2CCN(C(=O)CO)CC2)nc1 +CCN(C(=O)Cc1cccc(N)c1)c1ccccc1 +O=C(CNS(=O)(=O)N1CCCCC1)N1CCCc2ccccc21 +Cn1nnc2cc(C(=O)NCc3ccccc3-n3ccnc3)ccc21 +O=C(NCc1noc(Cc2ccccc2)n1)C1CCCC1 +CCCC(=O)NCCn1nc(C(F)(F)F)n(C)c1=O +Cc1ccc(C)c(C(=O)OCC(=O)NCC(C)C)c1 +O=C(Nc1cc[nH]n1)c1[nH]nc(-c2ccccc2)c1Br +CCN(Cc1cc(-c2ccc(F)cc2)on1)C(=O)C(C)C +COc1cc(C)c(C(=O)NCc2cccc(C)c2)cc1OC +Cc1ccc(C)c(C(=O)C(C)Sc2nnc(Cn3cncn3)o2)c1 +O=C(CNC(=O)CC1C=CCC1)NCc1ccccc1 +Cc1ccc(N)c(S(=O)(=O)NC(C)(C)C)c1C +CC(O)CC(C)CNC(=O)Nc1ccccc1S(C)(=O)=O +O=C(c1cn2cccnc2n1)N1CCC(c2nc3ccccc3o2)CC1 +Cc1nc2c(c(N3CCC(O)C3)n1)Cc1ccccc1OC2 +Cc1cccc(CS(=O)(=O)NCC#Cc2ccccc2N(C)C)c1 +CCCC(=O)N1CCCC(C2CC(C(F)F)n3nc(C)cc3N2)C1 +COCCCN1CC2(CCN(C(=O)c3ccccn3)CC2)CC1=O +COc1cc(OC)c(NC(=O)c2cc(C)no2)cc1Br +Cc1ccc(C)n1-c1c(C(=O)OC2CC3CCC2C3)cnn1C +Cc1ccc(S(=O)(=O)NCc2cn(C)nc2C)cc1 +CC(C)(C)c1cc(-c2nc3c4ccccc4ncn3n2)n[nH]1 +O=C(CN1CCOC(c2ccccc2)C1)N1CCCCCC1 +COCC(C)NC(=O)c1cc(-c2ccc(C)s2)[nH]n1 +COc1ccc(-n2ncc(C(C)(C)O)c2C)c(OC)c1 +COC(=O)c1c(NC(C)=O)cccc1NC(C)=O +CCOc1ccc(OCC(=O)Nc2nnc3n2CCCS3)cc1 +CCC(C)N(CCOC)C(=O)c1c(C)cccc1N +CC(=O)NC(C)C(=O)N(C)CC(=O)Nc1ccc(Cl)c(Cl)c1 +Cc1nc(C)c(C(C)N(C)C(=O)c2ccc(C)c(F)c2)s1 +O=C(Nc1cnc2n1CCCC2)c1ccc(CSc2ncn[nH]2)o1 +O=C(Cc1ccc(O)cc1)N1CCCC1c1ccccc1 +CCn1cnnc1CNC(=O)Nc1cccc2ccc(C)nc12 +O=C1COc2cc3cc(C(=O)c4ccccc4O)cnc3cc2N1 +COCCNS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)on2)o1 +Cc1noc(COCC(=O)NCCc2ccccc2Cl)n1 +CCOC(=O)c1ccccc1NC(=O)CSc1nc(N)cc(N)n1 +O=C(Nc1nc[nH]n1)C1CC1c1ccc(Cl)cc1Cl +Cc1ccc(NC(=O)CCn2c(C)csc2=O)cc1C(F)(F)F +COC(=O)C1=C(c2ccccc2)NC(=O)NC1c1ccco1 +COCC(O)CNC(=O)Cc1ccccc1C(F)(F)F +OC(CNc1ccc(Cl)cc1)c1ccc(F)cc1 +Cc1nn(-c2ccc(NC(=O)C3CCCO3)cn2)c(C)c1Cl +N#CCOc1cccc(CC(=O)Nc2ccc3[nH]nnc3c2)c1 +COc1ccccc1CN(C(=O)c1ccc(C)cc1)C1CC1 +Cc1c(Br)cc2c(c1C)OCCC(=O)N2C +CC(C)N1CCN(C(=O)c2cn(C)nc2-c2ccc(F)cc2F)CC1 +O=c1onc(-c2ccccc2)n1Cc1ccc(-n2cccn2)cc1 +Cc1ccc(S(=O)(=O)n2ccc(C(=O)Nc3ccncc3)c2)cc1 +O=C(Cn1c(CO)cnc1SCc1ccccc1)NC1CC1 +Cc1cccc(NC(=O)N(C)Cc2cn(C)nc2C)c1 +COc1cccc(NC(=O)c2cc3ccc(OC)cc3oc2=O)c1 +N#Cc1cc(Br)ccc1OCCN1CCOCC1 +Cc1c(-c2nccn2Cc2nccs2)oc2ccccc12 +Cc1ccc(NC(=O)CSc2nnc(C)n2C)cc1 +CC(Cn1ccnc1)NC(=O)c1cccc(C(N)=O)c1 +CN1C(=O)CCCC12CCCN(C(=O)c1ccc3ccccc3n1)C2 +CCCCOC(=O)c1cccc(-n2nnc(C#N)c2C)c1 +Cc1cc(F)ccc1NC(=O)CNC(=O)C(C)C +COc1ccc2c(c1)OCC(C(=O)NCCc1nc(C)c(C)s1)C2 +COCCC1COC2(CCN(C(=O)Cn3cccn3)C2)C1 +CCCCNC(=O)Nc1cccc(C)c1C(=O)N1CCCC1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)C1CCCC1 +CC(c1ccccc1F)N(C)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +COc1cccc(-c2nc(-c3cc4cc(OC)ccc4[nH]c3=O)no2)c1 +COC(=O)N1CCC(Nc2nccc(OC)n2)CC1 +CCOc1cc(NC(=O)NCc2ccc(S(C)=O)cc2)ccc1C +CC(C)N(CCCNC(=O)c1cc2ccccn2c1)S(C)(=O)=O +COc1ccc(O)c(C(=O)N(C)CCc2ccc(F)cc2)c1 +Cc1nnc(N2CCC(C(N)=O)CC2)c(C#N)c1C +CSc1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +CN(c1ccc2ccccc2n1)S(=O)(=O)c1ccccc1F +CCS(=O)(=O)c1ccccc1NC(=O)NCc1ccco1 +COC(=O)C(c1ccccc1)N1CCCC(C(C)O)C1 +Cc1cc(C)nc(-c2cccc(-c3ccn(CC(N)=O)n3)c2)n1 +O=S(=O)(NCC#Cc1ccccc1)c1cn[nH]c1 +OC(Cn1ccnc1-c1cnccn1)c1ccccc1F +CC(C)(C)C(=O)NCc1ccc(-n2cncn2)nc1 +CN(C(=O)COc1c(N)cc(Cl)cc1Br)C1CC1 +Cc1cc(C(=O)Nc2c(C)nn(Cc3ccccc3)c2C)no1 +O=C(Cn1ncc2ccccc2c1=O)Nc1ccncc1 +Cc1cccnc1NC(=O)Nc1ccc(F)cc1F +Oc1ccc(C2NCCc3cc(F)c(F)c(F)c32)cc1 +O=C(c1cccnc1)N1CCc2ccc(=O)n(CC3CC3)c2CC1 +Cc1ccc2c(c1)CCCN2C(=O)c1ccc(C)nc1 +CSc1nc2c(c(C(F)(F)F)c1C#N)CCc1occc1-2 +CCOCc1ccc(CNC(=O)N2CCC(C(N)=O)C2)cc1 +O=C(c1ccc2ccccc2n1)N1CCC(CO)CC1 +COCCN(C)C(C#N)c1ccc(Br)cc1 +O=C(NCc1cccc(NC(=O)C2CC2)c1)c1ccccc1O +CS(=O)(=O)N1CCC(C(=O)Oc2cccc3ccccc23)CC1 +CCNC(=O)c1ccc(CNC(=O)NC2CCc3ccccc32)cc1 +O=C(c1cc2ccccc2[nH]1)N1CCCC(C(=O)N2CCOCC2)C1 +Cc1csc(C(C#N)C(=O)C(C)(C)c2ccccc2)n1 +CSc1ccc(CNC(=O)c2cnc3scc(C)n3c2=O)cc1 +COCC(C)(NC(=O)c1cc(OC)c(OC)cc1C)c1ccccc1 +Cc1cccc2c(CC(=O)NCc3ccc(-n4ccnc4)cc3)c[nH]c12 +Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCCCn1ccnc1 +CCOc1ccccc1NC(=O)N(C)Cc1ccco1 +COc1ccc(C(O)C(=O)N2CCC(C)CC2)cc1 +COCC(C)NC(=O)c1cc(Cl)c(NC(C)=O)cc1OC +CCc1nnc(CNc2ccc(-c3cccc(F)c3)c(F)c2)o1 +O=C(C1CCCO1)N1CCC(CO)(Cc2ccc(Cl)cc2)CC1 +C=CCN1CCN(C(=O)COc2ccc(Cl)cc2C)CC1 +CCC(CC#N)NCc1sc(N(C)C)nc1OC +Cn1c(Sc2cnccn2)nnc1-c1ccc(F)cc1 +NC(=O)C1CCCN(C(=O)CNc2ccc(Cl)cc2)C1 +Cc1ccc2nc(-c3ccc(S(C)(=O)=O)cc3)cn2c1 +NS(=O)(=O)c1ccc(CNC(=O)NCC2CCOC2)s1 +O=C(Nc1cccc2ccccc12)N1CCCC(O)(CO)CC1 +CC(NC(=O)Nc1ccn(-c2ncccc2Cl)n1)C1CCC1 +CC(=O)Nc1nc(C2CCCN2c2cc(C)ncn2)cs1 +CCOc1ccccc1NC(=O)c1cc(N)c[nH]c1=O +Cc1csc(NC(=O)CCSc2ccc(F)cc2)n1 +COc1cc(N)cnc1Nc1ccc(F)cc1F +O=C(CCC1CCCC1)Nc1ccn(-c2ncccc2Cl)n1 +CS(=O)(=O)NCCNC(=O)c1ccc[nH]c1=O +CCc1ncc2c(n1)CN(C(C)c1nc3ccccc3c(=O)[nH]1)CC2 +CCC(CC)C(NC(=O)NCC(=O)N1CCCC1)c1cccs1 +O=C(NCCc1cccc(Cl)c1)c1cccc(-n2cnnn2)c1 +Cc1nc(NC(=O)c2csnn2)sc1C(=O)OCC(C)C +CC(=O)N1CCC(C(=O)NC(C)C23CC4CC(CC(C4)C2)C3)CC1 +O=C(CSc1nncs1)Oc1ccc(Br)cc1F +O=C(CCc1ccccc1)Nc1ccc(Cl)cn1 +O=C(CNC(=O)NCC(O)c1ccco1)Nc1ccc(Cl)cc1 +COc1ccc(-c2n[nH]cc2CN2CCOCC2CC(C)C)cc1 +CCC(=O)N1CCc2cc(C(=O)C(C#N)c3nc(C)cc(C)n3)ccc21 +CCN(CCCN1CCOCC1)C(=O)c1cnn(CC)c1 +Cc1nn(C)c(C)c1C(=O)Nc1ccc(C(=O)N(C)C)cc1 +COc1ccc(C(O)COc2ccccc2N)c(OC)c1OC +CCOC(=O)CNS(=O)(=O)c1ccc(C)cc1 +COc1ccc(C(C)=O)cc1CN1CCN(c2ccc(O)cc2)CC1 +O=C(C1CC1)N1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +Cc1nn(C)c(C)c1CC(C)NC(=O)N1CC(C)c2ccccc21 +COC(=O)CCCCCNC(=O)N1CCC(C)CC1 +COC(=O)c1cc(N)cc2nc(-c3ccc(Cl)cc3)oc12 +Cc1ccc(C)c(NC(=O)CCC(=O)Nc2nccs2)c1 +O=C1CC2(CCN(S(=O)(=O)C3CC3)C2)CN1c1ccc(F)cc1 +Cc1ccc(C(=O)NCc2nc(-c3ccc(F)cc3)n[nH]2)cn1 +CC(NC(=O)c1ccc(-n2ccnn2)cc1)C(=O)N1CCCCC1C +C=CCN(CCc1ccccc1)C(=O)c1ccc(-n2ccnn2)cc1 +CCCn1nnnc1CSc1cc(C)ccc1C +CC1CCN(C(=O)Cc2csc(N3CCCC3=O)n2)C(C)C1 +CC(Cn1cc(Cl)cn1)C(=O)N1CCN(C)CC1c1ccccc1 +Cn1cc(-c2nc(C(=O)NCc3cccc4ccccc34)cs2)cn1 +O=C(NCC(O)c1cccs1)C1(c2ccccc2)CCOCC1 +CN(C1CC1)S(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCN(CC)C(=O)c1cc2c(=O)n3cc(C)ccc3nc2n1C +CCN(Cc1cccc(C)c1)C(=O)c1cn2cccnc2n1 +CCOC(=O)C1CCN(C(=O)c2ccc(N(C)C)cc2)CC1 +CCOCCNS(=O)(=O)c1cccc2c(N)cccc12 +CC(NC(=O)c1cc(F)c(F)c(F)c1F)C(N)=O +COC(=O)c1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1 +CN(Cc1cccc(C(N)=O)c1)C(=O)c1ccccn1 +Cc1cccc(NC(=O)Cc2csc(-c3ccco3)n2)n1 +O=C(CNC(=O)Cc1ccccc1)NCc1ccccn1 +Cc1cc(C)c(NC(=O)Cn2c(=O)oc3ccccc32)c(C)c1 +CCn1nc(C)c(NCc2cc(OC)c(OC)cc2SC)c1C +COc1ccc(CN2CC3OCC(=O)N(CC(N)=O)C3C2)cc1 +CCOc1ccc(C(=O)Nc2cnc(N3CCCC3)nc2)cc1 +Cc1cc(-c2cccnc2)nc(-c2ccccc2O)n1 +CCCCCNC(=O)CNC(=O)c1ccc2c(c1)OCO2 +O=C(NCC1CCOC1c1ccccc1)NC1CCCCC1CO +Cn1c(=O)c2c3c(sc2n2c(SCC(N)=O)nnc12)CCCC3 +CCOC(=O)CC1(O)CN=C(c2ccccc2C)C1 +Cc1cc(Br)cnc1NCCN1CCCS1(=O)=O +CC1(C)CS(=O)(=O)N(c2ccc3c(c2)OCCO3)C1=O +COc1ccc(Br)cc1-c1cc(C)nc(=O)[nH]1 +O=C1CCc2cc(OCC(=O)N(C3CCCC3)C3CC3)ccc2N1 +Cc1cccc(C(O)c2cc(C)cc3c2NC(=O)C3C)c1 +COc1ccccc1C(=O)NCCC(=O)N1CCNCC1 +CCCn1c2c(cc(-c3nnc(NC)s3)c1=O)CCC2 +O=C(NCCNc1ncccn1)NC1CCc2ccccc21 +O=C(NCc1ccc(F)cc1Cl)c1ccnc2[nH]ccc12 +CN(Cc1ccc2c(c1)OCO2)c1ncnc2c1cnn2C +CC(=O)Nc1ccc(C(=O)Nc2ccc(N(C)C)nc2)cc1 +CCOC(=O)CCC(C)NC(=O)c1cc(C)cc(C)c1O +O=C(Nc1ccc(N2CCN(Cc3cccs3)CC2)nc1)C1CC1 +COc1ccccc1Cn1ccnc1Cc1ccccc1N +Cc1sc2nc3n(c(=O)c2c1C)CCC3=Cc1cccs1 +CCCN(CC1CCCO1)C(=O)c1[nH]nc(-c2ccccc2)c1C +Cc1cc(CN(C)CC2(CN3CCOCC3)CCCCC2)no1 +CCC(C)(C)C1CCC(NC(=O)Cn2c(C)c(C)sc2=O)CC1 +Cc1nccc(CNC(C)c2cccc(C#N)c2)n1 +CCS(=O)(=O)N(CCO)c1cccc(C#N)c1 +Cc1nc(-c2cccc(NCc3ccc[nH]3)c2)n[nH]1 +CCOC(C)c1noc(C2CCC(=O)N(c3ccc(C)c(C)c3)C2)n1 +CCCCN(CCOC)C(=O)c1cnc2ccc(C)cn12 +Cc1c(N)cccc1-c1nn2c(CC(C)C)nnc2s1 +CC1CC(Sc2nnc(-c3ccccc3)o2)C(=O)O1 +O=C(NC1CCc2ccccc21)C(Cc1ccccc1)n1cnnn1 +Cc1cccc(C)c1NC(=O)c1ccc(-c2cscn2)cc1 +Cc1ccccc1NC(=O)C1CC1c1ccc2c(c1)OCCO2 +O=C(NCc1cccnc1-n1cncn1)c1cn2ccccc2n1 +O=C(NC1CCCc2[nH]c(=O)ccc21)C1CCCC1 +O=C(Cn1nc2n(c1=O)CCCCC2)Nc1nncs1 +FC(F)(F)c1nnc2ccc(NCCCN3CCOCC3)nn12 +Cc1occc1C(=O)N1CC2COCC2(COCc2ccncc2)C1 +COCCN1C(=O)COC2CN(Cc3cnc4ccccc4c3)CC21 +CC(C)Oc1ccc(Cl)cc1C(=O)NCC(=O)NC1CC1 +Cn1cc(Br)cc1C(=O)NCc1ccnn1C +CC(C)(C)OC(=O)N1CCCCC1CNc1ncccc1C#N +Cc1ccc2ncc(C(=O)Nc3cccnc3OC(C)C)n2c1 +O=c1c2ccsc2ncn1CC(O)c1cc(Cl)ccc1Cl +CCC1COCCN1S(=O)(=O)c1cn[nH]c1C +CC(C)(C)CC(=O)N1CCCC1C(=O)NCc1ccco1 +COC(=O)c1ccc(F)c(NC(=O)NCc2ccc(F)cc2)c1 +CC1CN(C(=O)C2CN(C(=O)c3ccc4c(c3)OCO4)C2)CC(C)O1 +COCC1CCCN(C(=O)c2cc(-c3ccc(F)cc3)n[nH]2)C1 +COC(=O)COc1ccc(C2CC(O)=Nc3c2cnn3C)cc1OC +O=C(CNc1ccccc1)Nc1ccc2c(c1)OCCO2 +CC1CC(C)CN(C(=O)C2CCCN(S(C)(=O)=O)C2)C1 +CC(NC(=O)c1occc1CSc1ccccc1)c1ccncc1 +CNC(=O)C(Cc1ccc(F)cc1)c1ccc(N)cc1 +CN(C)C(=O)Oc1cccc(NC(=O)N2CCOCC2)c1 +O=C(Cc1ccccc1Cl)Nc1cnc2n1CCCC2 +CNC(=O)NCC(=O)NCc1cccc(Cn2cccn2)c1 +N#Cc1ccc(CNC(=O)c2cc(C(N)=O)cs2)cc1 +CC(Oc1cccc(Cl)c1)C(=O)NCC(=O)NC(C)(C)C +Cc1noc(C)c1NC(=O)NC(c1cccs1)C(C)C +N#Cc1ccccc1NC(=O)CCn1cnc2sccc2c1=O +Cc1ccc(-c2nc3nc4c(cn3n2)C(=O)CC(c2ccco2)C4)cc1 +CCN(CC(C)C#N)C(=O)c1cc(Cl)ccc1F +Cc1nc(CNC(=O)Cc2c[nH]c3ccc(Cl)cc23)c(C)s1 +CC(C(=O)c1ccc(N)cc1)N1CCC(C(N)=O)CC1 +O=C(c1cccnc1)N1CCCCC1CCc1ccccc1 +O=C(NCCNc1cccnc1)C1CCN(C(=O)C2CCCC2)CC1 +CC(=O)NC(C)C(=O)NCC(C)(C)c1ccccc1Cl +Cc1nc(C(=O)Nc2cccc3cn[nH]c23)cs1 +O=C(Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1)C1CC1 +Cc1c(C(=O)Nc2ccnn2C2CCCC2)[nH]c2c1C(=O)CCC2 +CN(C)CC(Cc1ccccc1)NCc1ccc(C#N)cc1 +CCc1[nH]c(C(=O)NC(C#N)C2CCOC2)c(C)c1C(=O)OC +CC(C)(C)OC(=O)NCC1CCCN(C(=O)Nc2cccnc2)C1 +CC(=O)Nc1ccc(Cl)c(NC(=O)C(C)NC(N)=O)c1 +CCN1C(=O)COC2CN(C(=O)c3cnoc3C)CC21 +COc1ccccc1NCc1ccc(OC(F)F)c(OC)c1 +Cc1csc(NC(=O)N(Cc2cccs2)CC2CCCO2)n1 +Cc1ccc(NC(=O)CCC2CCCO2)c2[nH]ncc12 +O=C(CSc1ccc2ccccc2c1)Nc1cccnc1 +CC(C)(C)C(=O)N1CCCC1C(=O)NCc1ccoc1 +COc1cc(C)sc1C(=O)N1CCN(C(=O)C2CCCO2)CC1 +Cc1cc(CN2CCN(C(=O)NC3CCCCC3C)CC2)no1 +Cc1c(C(=O)Nc2cccc3cnccc23)cnn1-c1ccccc1F +CCS(=O)(=O)NCCCNC(=O)c1cccc(Cl)c1Cl +Cc1n[nH]c(C)c1S(=O)(=O)NC(C#N)CC(C)C +O=C(Nc1cccc(Br)c1)C1CCCO1 +CCOC(=O)c1[nH]nc2c1CCOc1c-2ccc(C)c1C +OCc1cc(CC2(NCc3cccc4c3OCO4)COC2)no1 +Cc1cc(C(=O)Nc2c(Cl)cccc2Cl)no1 +CC(=O)Nc1ccc(S(=O)(=O)N(C)Cc2cn(C)nc2C)cc1 +CC(=O)Nc1ccc(C)n(CC(=O)NCc2cccc(C)c2)c1=O +O=C(C1CC1)N1CCC(S(=O)(=O)c2ccccc2)C1 +CS(=O)(=O)NCCn1ccc(-c2ccncc2)n1 +COc1cccc(CNC(=O)Cn2nnc(-c3ccsc3)n2)c1 +CC(C)Oc1ccc(C(=O)N2CCC(Oc3cccnc3)CC2)cc1 +N#Cc1ccsc1NCc1cc(Cl)ccc1F +Cc1ccc(NC(=O)CSc2cc(N3CCOCC3)ncn2)cc1 +CC(C)CNS(=O)(=O)c1ccc(C(=O)NCCO)cc1 +CC(=O)NCc1ccc(C(O)c2ccc(F)cc2)cc1 +CC(C)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(N)=O +COc1ccccc1C(C)Nc1ccc(NC(C)=O)cc1 +CC(C)(C)n1ncc2c(=O)n(NC(=O)c3ccco3)cnc21 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)N(C)Cc3cc(C)on3)ccc21 +COC(=O)C1CC(OC(=O)c2ccncc2)CN1 +CCn1cc(S(=O)(=O)N2CCc3ccccc3C2)cn1 +O=C(Nc1nnc(-c2ccccc2)o1)NC1CCCCC1 +CN(Cc1cnn(C)c1)C(=O)CCCn1c(=O)oc2ccccc21 +Cc1sc(NC(=O)CC(C)(C)c2ccccc2)c(C(N)=O)c1C +COC(=O)c1cc(OC)c(OC)cc1NC(=O)CC1CC2CCC1C2 +FC(F)(F)c1cc(Br)c2cnccc2n1 +CC(=O)Nc1cccc(NCC(=O)NCCC2=CCCCC2)c1 +CS(=O)(=O)N1CCN(c2ncnc3nc[nH]c23)CC1 +Cc1ccc(NC(=O)CCC(C)C)cc1S(C)(=O)=O +CCc1nnc(NC(=O)c2cc3c(s2)CCC3)s1 +O=c1[nH]c(CN2CCCCCC2)nc2cc(Cl)ccc12 +CCCc1cnc2c(c1SC(C)C)c(=O)n(C)c(=O)n2C +Cc1nc(-c2coc(CN3CCOCC3)c2)n(-c2ccccc2)n1 +O=C(N1CCCCC1)N1CCN(S(=O)(=O)c2ccc(F)cc2)C1 +COCCn1cccc(-c2nnc(NC(C)C)s2)c1=O +Cc1ccc(CC(=O)Nc2cccc(-n3nnnc3C)c2)cn1 +CCOc1ccc(NC(=O)CNC(=O)c2ccc(F)cc2F)c(C)c1 +C=CCN(Cc1ccccc1)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +Cc1noc(C2CCCCN2C(=O)Cc2c(C)noc2C)n1 +Cc1ccc(NC(=O)c2csc(Nc3ncccn3)n2)cc1C +Cc1ccc(C(O)CCNc2cccc(F)c2)cc1 +COc1ccc2c(ccn2CCNC(=O)c2cccnc2)c1 +CCCc1noc(C2CC(=O)N(Cc3ccccc3)C2)n1 +CCOc1ccc(C(=O)Nc2c(C)nn(C)c2C)cc1OC +COCc1nc(C)c(CNC(=O)C(C)n2cnc3ccccc32)s1 +CCOc1ccccc1NCC(=O)NC(C)(C#N)C(C)C +Cc1ccc(-c2cc(CC#N)c(=O)n(C)n2)cc1C +Cc1nc2ccc(C(=O)Nc3ccc(C(N)=O)cc3)cc2nc1C +N#Cc1ccc(F)c(CN2CCc3cc(S(N)(=O)=O)ccc32)c1 +O=C(c1ccc(Cn2cnnn2)cc1)N1CCc2ccccc2C1 +O=S(=O)(NC1CC=CC1)c1ccc(OCC(F)F)cc1 +CCC(=O)Nc1ccnn1Cc1ccccc1Br +CCn1c(=O)sc2cc(NC(=O)c3ccco3)ccc21 +Cc1ccc(C(=O)NCC(O)c2cccc(Cl)c2)cn1 +CC(C)C(=O)NCC1CCN(C(=O)c2cnccn2)CC1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1csc(-c2ccco2)n1 +O=C(Nc1ccc(-n2cncn2)cc1)c1cc(Cl)c[nH]1 +CSc1cccc(NC(=O)NCc2cccnc2)c1 +Cn1c(Nc2ccc(Br)cc2)cc(=O)n(C)c1=O +COc1cncc2c1CCCN2C(=O)OC(C)(C)C +Cc1ccc(C(C)N(C)C(=O)C2CCN(c3cnccn3)CC2)cc1 +O=C(CCCc1nc(C2CC2)no1)NC1CCCC(C2CC2)C1 +O=C1CCCN1c1cccc(CNc2ncccn2)c1 +CCCCC(=O)N(C)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O +CCCCNS(=O)(=O)c1cc2c3c(c1)CCC(=O)N3CCC2 +Cc1nc(S(=O)(=O)NCCc2ccccc2)c(C#N)c(C)c1Cl +COc1cc(F)cc(CNC(=O)NCc2ccn(C)c2)c1 +CCn1nc(-c2csc(NCC(C)C)n2)ccc1=O +CC1(C(=O)NCc2ccccc2)CCC(=O)N1CCc1ccccc1 +CC(C)CC(=O)NCCNS(=O)(=O)c1cccc2nonc12 +COC(=O)C1(NC(=O)c2ccco2)CCCCCC1 +COc1ccc(C(=O)CNC(=O)C2CCCC2)cc1Cl +O=C(c1cc2ccccc2oc1=O)N(CCc1cccs1)C1CC1 +CNC(=O)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +COC(=O)CCCn1c2c([nH]c1=O)CC(C(=O)OC)CC2 +CC(NC(=O)c1cnccn1)c1ccc2c(c1)CCCC2 +Cn1cc(C(=O)OCCc2c[nH]nc2C(F)(F)F)c(C(C)(C)C)n1 +CC1CCCCC1N(C)C(=O)Nc1ccc(-n2cncn2)nc1 +CN1CC(C(=O)NCc2ccc(OCC(F)(F)F)nc2)CC1=O +COc1ccc(CN(C(=O)c2ccc(OC)cc2)C2CC2)cc1 +CC(C(=O)N1CCc2cc(F)ccc2C1)c1ccc2c(c1)OCCO2 +O=C(NCCc1ccccc1F)c1ccc(F)cc1 +Nc1ncccc1C(=O)N1CCN(c2ccccc2F)CC1 +COc1c(OC(C)C)ccc2c1C(C1CCCO1)NCC2 +O=C(CS(=O)(=O)c1ccc(F)c(F)c1)Nc1cccc(F)c1 +Cc1cc(C)n(-c2cccc(C(=O)NCCC3(O)CCCC3)c2)n1 +C#Cc1cccc(NC(=O)c2cnn(-c3ccccc3)c2)c1 +COC(=O)C(NC(=O)c1[nH]ncc1Br)C(C)(C)C +CC(=O)c1cccc(NC(=O)COC(=O)c2ccc(F)cc2)c1 +CCCCCNC(=O)c1nc(C(C)C)ncc1Cl +CCc1cccc(CC)c1NC(=O)c1cscn1 +COCC(C)CNC(=O)NCC#Cc1ccccc1 +COCN1C(=O)C(Cc2ccccc2)Oc2ccc(O)cc21 +O=C1CCCCCN1CC(=O)N1CCCC(OCc2ccccn2)C1 +O=C(CCNS(=O)(=O)c1cccs1)N1CCCCC1 +CCc1cc(C(=O)NC2(COC)CCCC2)[nH]n1 +CN(Cc1ccc(O)cc1)C(=O)COc1ccc(C(F)(F)F)cc1 +O=C(C1CCCO1)N1CCc2onc(-c3ccccc3F)c2C1 +CS(=O)(=O)c1ccc(C(=O)N(CCO)C2CC2)cc1 +COc1ccc(C2(CNC(=O)c3cccs3)CCOCC2)cc1 +CN(CC(=O)OCc1cnn(C)c1)Cc1ccccc1 +N#CCCN(C(=O)Nc1cccc(Cn2cccnc2=O)c1)C1CC1 +O=C(Nc1nncs1)c1ccc(Oc2ccccc2)cc1 +Cc1cc(C)c(S(=O)(=O)N2CCCC2c2nc(C)no2)c(C)c1 +COc1ccc(CCNC(=O)c2c(F)cccc2F)cc1 +COCC1CN(C(=O)c2ccnnc2)Cc2cn(CC3CC3)nc21 +C=CCNC(=O)Nc1ccc(NC(=O)OC(C)(C)C)cc1 +CN(Cc1ccccc1Cl)C(=O)c1ccc(CNC(N)=O)cc1 +CC(C)n1nccc1C(=O)N1CCC(OCc2ccccc2F)CC1 +CC(=O)Nc1cc(-c2ccc(CO)o2)ccc1Cl +C=CCn1nnnc1SC(C)C(=O)Nc1ccc(C(C)=O)cc1 +CCc1ccc(C(COC)NC(=O)N(C)C(C)C)o1 +Cc1ccc(Cl)cc1-c1nc2cc(CO)ccn2c1N +N#Cc1ccc(NC(=O)c2csc(Nc3ncccn3)n2)cc1 +Cc1ccc(CCSc2nc(C)c(CCO)c(=O)[nH]2)cc1C +O=c1cc(C(F)(F)F)c2cc3c(cc2o1)NCCC3 +Cc1ccncc1NC(=O)NCc1cc(=O)[nH]c2ccccc12 +O=C(Nc1cccc(-c2nnco2)c1)c1ccc(F)cc1 +CC(=O)Nc1cc(NCc2nc(Cc3ccccc3)no2)ccc1C +Cc1cc(C(=O)NC2CCc3c(F)cccc32)c(C)s1 +CC(=O)Nc1ccc(CN(C)C2CCCc3nc(C)sc32)cc1 +COc1ccc2c(c1OC)C(C(O)CO)NCC2 +COc1ccc(-c2cc(C(=O)Nc3ccccc3)n[nH]2)c(OC)c1 +COc1ccc2c(c1)N(S(=O)(=O)c1ccccc1)CCC2=O +CC(C)Cc1cc(C(=O)N2CC(OCc3ccc(F)cc3)C2)on1 +COc1cc(Cl)c(C)cc1NC(=O)NCCc1ccccn1 +COc1cc(NC(=O)c2ccc(C)c(N)c2)cc(OC)c1OC +Cc1[nH]ncc1CCCNC(=O)NCC(O)c1ccccc1F +N#Cc1ccc(N2CCC(Sc3ccccc3)C2=O)cc1 +CC(=O)c1cccc(S(=O)(=O)N2CCOc3ccccc32)c1 +CCOc1ccc(F)c(C(=O)Nc2cccnc2)c1F +CC(=O)N1CCc2cc(S(=O)(=O)CCC#N)ccc21 +Cc1cccc(Oc2cncc(C3CCCN(S(C)(=O)=O)C3)n2)c1 +c1cc(OCc2cc(-c3ccco3)on2)cc(-n2cnnn2)c1 +CN(C)C(=O)CCNc1ccc(S(C)(=O)=O)cc1 +CCCCn1nc(C(=O)OCC2CCCCO2)ccc1=O +CCC(C)C(NC(=O)CCc1ccsc1)C(N)=O +NC(=O)c1cc(NC(=O)c2cccc(F)c2)cc(C(N)=O)c1 +O=C(C1CC1)N1CCN(Cc2nc(-c3cccs3)cs2)CC1 +O=C(Cn1c(=O)[nH]c(=O)c2ccccc21)Nc1cccc2cccnc12 +CCC(C)(C)NS(=O)(=O)c1cccc2nonc12 +CCN(C)S(=O)(=O)NC1CCN(c2c(F)cccc2F)C1=O +O=C(NCc1cccs1)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CC(NC(=O)c1cc(Cl)ccc1Cl)C1CCCO1 +Cc1cc2c(cc1O)C(c1ccc(F)cn1)NCC2 +Cc1cc(C)c(S(N)(=O)=O)cc1C(=O)NC(C)(C)C +COc1cc(NC(=O)Nc2cc(OC)ccc2F)cc(OC)c1 +CC1Oc2ccccc2OC1C(=O)N1CCN(c2nccs2)CC1 +CCC(NC(=O)NCC1CC(=O)N(C2CC2)C1)c1cccc(Cl)c1 +CCCCNC(=O)Cn1c(=O)sc2ccccc21 +Cc1ccc(C)c(CN2C(=O)C(C)CS2(=O)=O)c1 +CCCNC(=O)C1CCCN(C(=O)c2ccc3c(c2)OCCO3)C1 +CCc1cccc(NC(C)C(=O)N2CCN(C(C)=O)CC2)c1 +O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)c1cccs1 +O=C(Oc1cccc2cccnc12)c1cccs1 +COc1ccc(N2C(=O)NC3CC2(C)Oc2ccccc23)cc1 +COc1ccc(CC2CNc3ccc(O)cc3O2)cc1 +CN(C)S(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2F)cc1 +Cc1cc(CNC(=O)Cc2ccc(-n3cnnn3)cc2)ccc1F +Cc1ccc(C(=O)NCCCN2CCCCCC2=O)c(=O)[nH]1 +CCc1onc(C)c1NC(=O)NCCC1=CCCCC1 +CCN(CC1CN(Cc2cccnc2)CCO1)c1cccnn1 +O=C1CC(C(=O)N2CCCS2(=O)=O)CN1Cc1ccccc1 +CC(C)c1cc(NC(=O)c2cc3ccccc3oc2=O)[nH]n1 +O=C(NCc1nnnn1C1CCCCC1)Nc1c(F)cccc1F +Cc1cccc(C)c1OCC(=O)Nc1ccc2c(c1)OCO2 +CCCC(C)(C)NS(=O)(=O)N1CC(C)CC(C)C1 +CCc1nc(-c2cccc(OC)c2OC)sc1C#N +CCC(=O)N1CCCN(C(=O)Nc2ccccc2COC)CC1 +Cc1noc(NC(=O)COc2ccccc2C#N)n1 +O=C(Nc1ccccc1C(=O)Nc1cnccn1)c1cccs1 +Cc1nn(C(=O)OC(C)(C)C)c2ncc(Br)cc12 +CCOC(=O)c1csc2nc(-c3ccccc3)[nH]c(=O)c12 +CN1CCC(NC2CCN(S(=O)(=O)C(F)(F)F)CC2)C1=O +CCOc1cc(CNC(=O)c2cnccn2)ccc1OC +CC(CC(=O)NC(C)C(N)=O)NC(=O)c1ccccc1 +CCC(=O)N1CCCc2ccc(NC(=O)CC(C)(C)C)cc21 +CSc1ncc(Cl)c(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)n1 +O=C(NC1CC1)c1ccc(-c2cccs2)[nH]c1=O +CCOCC1(Cn2ccc3[nH]c(=O)c(C#N)cc3c2=O)CC1 +O=C(NCc1ccco1)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +CCOCC(=O)NC(c1ccccc1)c1nnc(N2CCCC2)o1 +Oc1cccc(C2Nn3c(Cc4ccccc4)nnc3S2)c1 +CC(C)c1ccc(CCC(=O)N2CCC(=O)CC2)cc1 +Cc1ccc(N)cc1-n1cc(-c2ccccc2)nn1 +Cc1nn(C)cc1CN(C)C(=O)c1cccc(Cl)c1 +CCCn1c(=O)c2sccc2n2c(CCC(=O)NC(C)C)nnc12 +Cc1ccc(C(=O)N(C)C(C)c2ccccc2)s1 +CCc1nc(COC(=O)c2ccc3c(c2)nnn3CC)cs1 +NC(=O)c1ccc(NS(=O)(=O)c2ccc3ccccc3c2)cc1 +O=C1CC(C(=O)Nc2nccs2)N2C(=N1)Nc1ccccc12 +Cc1cc(C)n(CCN2CCN(CCn3nc(C)cc3C)C(C)C2)n1 +Cn1c(C(=O)NCc2ccccc2)nnc1-c1ccncc1 +CCOc1nc(C2CC2)nc(NCc2ccc(C)cc2)c1N +CC1(NC(=O)Cn2ccnn2)Cc2ccccc2C1 +COC(=O)CNC(=O)CCNC(=O)c1cccs1 +Cc1csc(C(NC(=O)Cc2ccc[nH]2)C2CC2)n1 +CC1(C)CN(CC(=O)NCCc2cnn(-c3ccccc3)c2)CCO1 +O=C(Nc1ccc(-n2nccc2C(F)(F)F)cc1)N1CCC(O)C1 +COC(=O)C1(NC(=O)C(C)NC(=O)c2ccccc2)CCCCC1 +O=C(NCCC1CCCO1)c1cc(Br)c[nH]1 +CC(C)n1cc(C(=O)Nc2cnn(C)c2)c2ccccc21 +N#Cc1ccnc(N2CCN(c3cccc(F)c3C#N)CC2)c1 +Cc1cc(O)c2c(c1)C(C=Cc1ccncc1)NCC2 +CN(CC(=O)NCC(C)(C)C(N)=O)c1ccc(Cl)cn1 +Cc1c(C(=O)OCC(N)=O)cnn1-c1ccccc1 +Cc1csc(COC(=O)c2cnn(-c3ccncc3)c2C)n1 +CC(C)N(Cc1ccccc1)C(=O)c1[nH]cc2c1CCC2 +COc1ccccc1S(=O)(=O)N1CCC(OC)CC1 +Cc1oncc1C(=O)NC1CCc2[nH]c(=O)ccc2C1 +NC(=O)NC(c1ccc2c(c1)OCCO2)c1ccccc1Cl +CC(C)c1cc(C(=O)N2CCC(c3cc4nccnc4[nH]3)CC2)[nH]n1 +COC(=O)C(C)N1CCNc2cc(Br)ccc21 +Cc1ccc(CN(C(=O)C(C)NC(N)=O)C(C)C)s1 +Brc1ccnc(Nc2cccnc2)c1 +COc1ccc(OC)c(NC(=O)c2ccc(-n3cccc3)cc2)c1 +CC(=O)c1c[nH]c(C(=O)NCc2cccc(N3CCCC3=O)c2)c1 +COc1ccc(CNC(=O)c2n[nH]c3c2CCCC3)cc1 +Clc1ccc2c(c1)C=Nc1c(ncnc1N1CCOCC1)O2 +Cc1ccc(-c2cc(C(=O)NCCc3nc(C)cc(=O)[nH]3)[nH]n2)cc1 +COc1cccc2c(=O)c(C(=O)NCCc3ccccn3)c[nH]c12 +Cn1cccc1C1CCCN1C(=O)NCCOc1ccc(C#N)cc1 +O=C1CN(C(=O)CCCNC(=O)c2ccsc2)CCN1 +CCOc1ccccc1CNC(=O)c1cnc(-c2ccccc2)nc1C +Cn1cc(CN(CCC#N)C2CCOCC2)c(C2CCCCC2)n1 +CC(C)c1ccc(N2C=NS(=O)(=O)c3cccnc32)cc1 +O=C(CCc1ccccc1O)NCC(O)c1ccc(Cl)cc1 +CCN(CCC(=O)OC)C(=O)Cc1ccc(F)cc1 +Cc1nc(C)c(C(C)N(C)C(=O)NCC2CCCO2)s1 +COCCn1cc(NS(=O)(=O)c2cccc(F)c2)cn1 +COc1ccc(NCc2ccc(-n3ccnc3)cc2)cn1 +COc1ccc(C(=O)Nc2cc(C)ccc2OC)cc1 +O=C(NCC1CCCO1)c1cccn1-c1cccnc1 +c1cncc(OCCNc2nc3nonc3nc2N2CCCCC2)c1 +Cc1ccc(CNC(=O)C(C)Sc2nccn2C2CC2)cc1 +CCCN1C(=O)NC(c2cccnc2)C(C(=O)OC)=C1CC +COc1ccc2c(c1)CC(C(=O)N1CCC3(CC1)OCCO3)CO2 +CC(C)CC(C)N(C)C(=O)CSc1ncc2ccccn12 +c1cc(-c2ccc(-c3nc(C4CCOC4)no3)cc2)n[nH]1 +COc1ccc(C(=O)NCCCC(=O)Nc2ccc(C)cc2O)cc1 +Cc1nc(-c2scc3c2OCCO3)n(-c2ccccn2)n1 +Cc1n[nH]c(O)c1C(C=Cc1ccccc1)c1c(O)n[nH]c1C +Cc1cccc(NC(=O)c2cnn3c(=O)c4c([nH]c23)CCC4)c1 +Cc1ccc(OC(=O)CCOCC2CCCO2)c(Br)c1 +Cc1noc(C)c1C(=O)N1CCN(C2CCCC2O)CC1 +CCSc1cc(C(=O)OCC(=O)Nc2ccccc2C)ccn1 +COc1ccc(F)cc1C(O)CCNc1ccccc1F +Cn1c(N2CCC(O)CC2)nc2sc3c(c2c1=O)CCCC3 +Cc1n[nH]c(C)c1C1COCCN1C(=O)c1ccc2c(c1)CCO2 +O=c1c(=O)n(-c2ccccc2)ccn1Cc1ccccc1 +CC(C)(C)c1ccc(-c2nnc(SCc3n[nH]c(=O)[nH]3)o2)cc1 +N#CC(C(=O)Nc1ccccc1F)c1ccc2ccccc2n1 +CCc1cc(NC2CC(=O)N(CCOC)C2)ncn1 +Cn1cc2ccc(F)c(C(=O)NCC(F)(F)F)c2n1 +CC(NC(=O)Cn1ccnc1)c1ccc2ccccc2c1 +COCC(C)NC(=O)NC1CCCN(c2cccc(F)c2)C1=O +CC(NC(=O)c1ccc(N(C)C)cc1F)C(N)=O +Cc1cnc(C(=O)Nc2c(-c3ccc(F)cc3)ncn2C)cn1 +Cc1cc(C(NS(C)(=O)=O)C(C)C)c(C)s1 +OCCSc1nnc(NC2CCCCC2)s1 +CCOC(=O)c1[nH]c2ccccc2c1NC(=O)COc1ccccc1 +Cc1ccccc1C1(CNC(=O)Nc2cnn(C)c2)CCOCC1 +Fc1cc(NCCN2CCOCC2)ccc1Cl +COc1cccc(COC(=O)C2CC=CC2)c1OC(F)F +COc1ccc(NC(=O)N2CCC(C)CC2)cc1-n1nnnc1C +COc1ccc(F)cc1NC(=O)Cc1csc(-c2cnccn2)n1 +CC(C)C(NC(=O)Cn1cccnc1=O)c1ccc(C(C)(C)C)cc1 +CC1(CNC(=O)CCCc2cc(F)ccc2F)COC1 +O=C(Nc1cnn(CC(=O)N2CCCOCC2)c1)c1ccccn1 +CCC(C)Oc1ccccc1-c1nc2c([nH]1)CCCNC2=O +O=C(CSc1nnc(NC2CC2)s1)N1CCOCC1 +Cc1csc(C(C#N)C(=O)Cc2ccccc2Br)n1 +CCOCC1CCCN(C(=O)c2cn3cccnc3n2)C1 +CSc1ccc(CN(C)C(=O)CSc2n[nH]c(N)n2)cc1 +Cc1ccccc1NC(=O)NCCC(O)c1cccs1 +c1cnnc(-c2noc(C(Cc3c[nH]cn3)n3cccc3)n2)c1 +CC1CN(Cc2csc(NC(=O)C3CCC3)n2)CC(C)O1 +COc1ccc(C(=O)OCC(=O)c2ccc[nH]2)cn1 +COc1cc(CNC(=O)c2c(C)oc(C)c2C)ccn1 +COc1cccc(C(=O)Nc2cc(C#N)cn2C(C)(C)C)c1 +C=CCNC(=O)c1cccc(S(=O)(=O)N=c2[nH]cccc2C)c1 +CN(Cc1cccc(Cl)c1)C(=O)CCC(=O)c1cccs1 +CCn1c(C)nnc1COc1cc(F)cc(Br)c1 +COc1ccc(OC)c(C(=O)Nc2cccc3c2oc(=O)n3C)c1 +CN(Cc1nc(-c2ccccc2)no1)C(=O)CCc1ccccc1 +Cc1ccccc1-c1cc(NC(=O)NCc2cccnc2)n(C)n1 +Cc1ccccc1NC(=O)C1Nc2cc(F)ccc2S(=O)(=O)N1 +CNc1nc(C)cc(-c2ccc(OC)c3ncccc23)n1 +CN(CC(=O)NC(C)(C)C)C(=O)CNc1ccccc1C(F)(F)F +CCCOC(=O)c1ccc2nc(NC)sc2c1 +CC(C)(CCC#N)CN1CCc2c(Br)cccc2C1 +CCC(NC(=O)N1CCCC(CO)C1)c1ccncc1 +COc1ccc(NC(=O)COC(=O)c2ccc(F)cc2)cc1 +CC(C)C(=O)NCCNC(=O)NCCC1=CCCCC1 +CCc1cc(=O)[nH]c(NCc2ccc(F)cc2F)n1 +CC(=O)N1CCCC(C(=O)Nc2ccc3oc(C4CC4)nc3c2)C1 +CC(C)(O)CN1CCN(C(=O)CCNc2ncccn2)CC1 +Cc1cn2c(CN(C)C(=O)c3ccc(C(N)=O)nc3)c(C)nc2s1 +O=C(Oc1ccc(-n2cnnn2)cc1)c1ccc(F)cc1Cl +CCc1nnc(CNc2c(F)cc(Br)cc2F)o1 +CCCc1cc(-c2ccnc3[nH]ccc23)nc(C)n1 +CCOc1ccccc1CCC(=O)N(C)CC(N)=O +O=C(C1CC1)N1CCN(Cc2nnnn2Cc2ccccc2)CC1 +CC(C)Nc1ncc(Br)c2c(N)cc(F)cc12 +Cc1cccnc1NC(=O)c1cc(Br)cs1 +CN(Cc1cccnc1)C(=O)Nc1ccc(-c2ncn(C)n2)cc1 +Cc1cc(CN(C)Cc2noc(C(C)C)n2)no1 +COc1ccc(C)cc1C(C#N)CCC(=O)NC1CC1 +COc1ccc(C#CCNC(=O)Nc2ccc3c(c2)OCO3)cc1 +CCN(CC)C(=O)c1ccc(NC(=O)c2cccc3cccnc23)cc1 +CCOC(=O)c1csc(Nc2cccc(N)c2)n1 +CCC(C(=O)Nc1cc(C)ccc1C)n1c(N)nnc1SC +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1C +O=C(C(O)c1ccc(F)cc1)N1CCCN(c2ccc(F)cc2)CC1 +CC(c1cnn(C)c1)c1nc(-c2ccc(F)cc2C(F)(F)F)no1 +CCCc1nc(NC2CCCC2)c(N)c(OCC(C)C)n1 +CCOC(=O)C1CCCN(C(=O)CCc2ccc(OC)cc2)C1 +CCOC(=O)Nc1cccc(C(=O)NCCc2cccc(F)c2)c1 +Cc1noc(C)c1C(=O)NC(C)c1ccc(F)cc1 +CC1(C)CNc2cc(C(=O)CN3CCOCC3)ccc2O1 +CC1CN(CC(=O)NC2CCCCNC2=O)C(C)CO1 +COc1cccc(CNC(=O)C(C)Oc2ccc(SC)cc2)c1 +OC1=Nc2nc(N3CCCCC3)sc2C(c2ccsc2)C1 +COc1ccc(N(CCc2ccccc2)C(=O)c2ccnc(C)n2)cc1 +COC(=O)c1cc(C)ccc1NCc1cncnc1 +CN(CC1CC1)C(=O)c1c(F)c(F)c(F)c(F)c1F +Cc1ccc(NC(=O)CN(C)C(=O)c2cc(F)cc(F)c2)cc1 +CC(=O)OC1c2ccccc2C(=O)N1Cc1ccccc1Cl +COc1cccc(C(N)=O)c1OCC(=O)N1CCCC1 +CS(=O)(=O)c1cc(C(=O)NC2CCCCC2)ccc1Cl +CC(=O)N1CCCN(C(=O)c2cc(C(N)=O)cs2)CC1 +Cn1ncc2c1N=C(O)CC2c1ccc(Cl)cc1Cl +Cc1c(-c2ccnc(Nc3ccc(Cl)cc3)n2)nnc2ncnn12 +CC(C)(C)c1nc2sc(C3CCCO3)nn2c1CO +CCCn1nc(C(=O)Nc2ccccc2C(=O)NC2CC2)ccc1=O +Cc1ccc(C(O)CCCC(=O)NC(C)(C)C)cc1 +Cc1cc(N)cc(C)c1NC(=O)c1cccc(OC(C)C)c1 +CCCCCC(=O)N1CCN(CC(=O)NC(C)C)CC1 +Cc1cc(NC(=O)CCn2c(-c3cccs3)noc2=O)no1 +Cc1cccc(NC(=O)CCCN(C)C(=O)OC(C)(C)C)c1 +O=C(NC1(c2ccccc2F)CC1)c1cccc(OCC(F)F)n1 +CSc1ccccc1C(=O)N1CC(c2nc3ccccc3[nH]2)C1 +NC(=O)C1(NC(=O)c2cccc(-c3ccoc3)c2)CCCCC1 +COC(C(=O)NC(C)c1cccc(N2CCCC2)c1)c1ccccc1 +N#CCCN(C(=O)CSc1nc(N)cc(=O)[nH]1)c1ccc(F)cc1 +CCCN1CCN(C(=O)c2n[nH]c3c2CCc2ccccc2-3)CC1 +CC(C)c1nn2c(CO)c(-c3cc(F)ccc3F)nc2s1 +Cc1nc(CN)nc(-c2ccc3c(c2)CC(=O)N3C)n1 +NC(=O)N1CCC2Nc3ccc(Cl)cc3C2C1 +N#Cc1ccccc1OCc1nnnn1-c1ccccc1 +COc1ccc(NC(=O)N2CCC(OC)CC2)cc1 +Cc1ccc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)cc1 +COCCCNC(=O)CCn1ncc2c(C)cccc21 +Cc1noc(-c2ccccc2NC(=O)Cc2ccccc2)n1 +N#Cc1cc(F)ccc1Cn1cnc(C2CCC2)cc1=O +COc1cccc(CC(=O)NC2CCN(c3ccccc3C#N)CC2)c1 +C=CCNS(=O)(=O)c1cccc(C(=O)NC(C)c2ccccc2)c1 +COc1cccc(C2CC2C(=O)Nc2cc(F)ccc2OC)c1 +CC(C)CCNC(=O)c1nn(C)c(=O)c2ccccc12 +CCCc1nc(CN2CCOCC2)sc1C(C)=O +CCOC(=O)N1CCC(Nc2nc3c(s2)c(C)nn3C)CC1 +CCOC(=O)C1N=C(C)C(CCC(=O)N2CCC(C)CC2)=C1C +CCCNC(=O)CCc1nc2ccccc2[nH]c1=O +C#CCn1c(=O)c(-c2ccccc2)nc2cc3c(cc21)OCCO3 +Cc1ccc(S(=O)(=O)CCC(=O)Nc2c(C)cc(C)nc2C)cc1 +O=C(Nc1ccc(F)cc1F)c1ccc(CN2CCOCC2)cc1 +COC(=O)C(NC(=O)OC(C)(C)C)C(O)c1ccc(N)cc1 +Cc1ccc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)c(O)c1C +Cn1cnnc1-c1cncc(NC(=O)c2scnc2C2CC2)c1 +CCN1CC(C(=O)N(CC)C23CC4CC(CC(C4)C2)C3)CC1=O +C=CCNC(=O)CCC(O)c1ccc(Cl)cc1 +Cn1cnnc1S(=O)(=O)Cc1ncc(-c2ccc(Cl)cc2)o1 +CCc1noc(CC)c1CNC(=O)c1nccnc1N +Nc1cc(Cl)c2c(c1)NC(=O)C(c1ccc(Cl)cc1)O2 +CC(NS(N)(=O)=O)c1ccc(C(F)(F)F)cc1 +CC(=O)N1CCc2cc(NC(=O)c3ccc(F)c(F)c3)ccc21 +CC(C)CC(=O)c1ccc2c(c1)NC(=O)C(C)CO2 +c1cnn(CC2CN(Cc3ccc4c(c3)OCCO4)CCO2)c1 +COc1ccccc1CNC(=O)c1cc(S(N)(=O)=O)c(C)o1 +CCOc1ccccc1OCC(=O)Nc1cc(OC)ccc1F +CCCNC(=O)NCc1cc(C(=O)OC)c(C)o1 +CCOC(=O)c1c(NC(C)=O)[nH]c2ccc(OC)cc12 +CCOC(=O)CN(C)C(=O)c1cc(C)ccc1F +Cc1noc(C(C)C)c1C(=O)N1CCCC(CNC(=O)C(C)C)C1 +CCC(Nc1ccccc1)C(=O)N1CCc2[nH]ncc2C1 +Cc1nc(C2(NC(=O)Nc3ccccc3F)CCCC2)no1 +Nc1c(-c2ccc(Cl)cc2)nnn1-c1cccc(O)c1 +COCCN(Cc1ccco1)C(=O)Nc1cc(C#N)ccc1OC +COCCNS(=O)(=O)c1ccc(NC(=O)C2CCC2)cc1 +O=C(NCC1(c2cccs2)CC1)c1ccc(F)c(F)c1 +Cc1ncc(C(=O)N(CC2CC2)c2cccnc2)c(Cl)c1Cl +CC(=O)Nc1cc(Cl)ccc1NC(=O)c1cc(F)ccc1F +O=C(CCn1c(C(F)(F)F)cc2cccnc21)NC1CCCC1 +CCOc1cc(=O)c(C(=O)NCC2CC2)nn1-c1ccc(F)c(F)c1 +COc1ccccc1OCCNC(=O)NCC(C)C +Cc1ccc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)cc1C +O=C(c1cscn1)N1CCN2CC(OCc3ccccn3)CC2C1 +CC(C)NC(=O)C(C)S(=O)(=O)c1ccc(C(F)(F)F)cn1 +CCC(NC(=O)NCc1cnn(C)c1)c1ccncc1 +CCn1c(=O)cc(OCC(=O)NCc2cccnc2)c2ccccc21 +O=C(c1cncc(-c2cc[nH]n2)n1)N1CCOCC1 +CC(C(=O)N1CCc2ccccc21)n1nc(-n2cccn2)ccc1=O +CC(NC(=O)c1cccc(-n2cnnn2)c1)c1nc2ccccc2o1 +CC1COCC(C)N1C(=O)CNC(=O)OCc1ccccc1 +Cc1occc1C(=O)N1CCC2C1CCN2c1nncs1 +CCn1cnnc1CNC(=O)c1ccc(Cl)cc1OC +O=C(Cc1ccccc1C(F)(F)F)N1CCN(CCO)CC1 +CCCN(C)S(=O)(=O)c1c(Cl)cccc1Cl +O=C(COc1ccccc1)N1CC(OCc2ccc(Cl)cc2)C1 +COC(C)C(=O)NC(C)c1ccc(Cl)cc1Cl +CN(C)c1ccc(C(=O)N2CCN(C(=O)CC(F)(F)F)CC2)cn1 +COc1ccc(CN(C)C(=O)c2cccc(OC(F)F)c2)cc1F +CCn1cc(CN2CCN(C(=O)C3CCCCC3)CC2)cn1 +Cc1cc(=O)c(C(=O)N(C)CCN(C)C(=O)OC(C)(C)C)c[nH]1 +NC(=O)CCCC(=O)NCC(=O)Nc1ccccc1 +Cc1cc(C)cc(OCCCN2CCN(C(=O)c3ccoc3)CC2)c1 +CN1CCN(C(=O)c2cc(-c3ccc(F)cc3)no2)CC1 +O=c1c(Cl)cc(-c2ccccc2)cn1CCCO +CC(C(=O)N1CCc2ccccc21)n1c(=O)oc2ccccc21 +CSc1ccc(CNS(=O)(=O)N2CCCCCC2)cc1 +CC(=O)N1CCc2ccc(NS(=O)(=O)c3ccccc3F)cc21 +COc1ccc(-c2nc(Cn3cncn3)n[nH]2)cc1 +COc1nc(C)c(-c2ccc(O)cc2)c(C)c1C#N +CNC(=O)c1cc(C)ccc1NC(=O)c1sc(CC(C)C)nc1C +Cc1ccc(OC(=O)Cc2c(C)nc3c(c2C)c(=O)[nH]n3C)c(C)c1 +CCOC(=O)C(C)=C1CCN(C(=O)OC(C)(C)C)CC1 +c1cncc(-c2ncc(-c3ccco3)c(-c3ccco3)n2)c1 +Cc1nn(C)c(C)c1NC(=O)c1cc(C)n(C(C)C)c1C +Cc1nc(C(=O)N2CCCC2)nn1-c1ccccc1Cl +Cc1nc(N2CCC(c3ncon3)CC2)c2cccnc2n1 +Cn1ccc(NC(=O)C2(c3ccc(F)cc3F)CCCC2)n1 +CN(CC(=O)NC(C)(C)C)S(=O)(=O)c1cccs1 +CCOC(=O)c1oc2ccccc2c1Cn1cnc(C(=O)OC)n1 +Cc1cc2ccccc2n1CC(=O)NC1CCN(C(=O)C(C)C)CC1 +CC(C)Oc1cccc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)n1 +O=C(OCC1CCCCO1)c1ccc(F)c(F)c1 +COCCCNC(=O)c1nnc(C(=O)Nc2ccccc2)s1 +CCOc1ccc2c(c1)CC(C(=O)N1CCOCC1C1CC1)CO2 +COCCn1cc(NCc2sc3ccccc3c2Cl)cn1 +CC(=O)Nc1ccc(F)c(C(=O)N2CC3CCC2C3)c1 +Cc1nc(-c2cc(C(=O)Nc3cnc4ccccc4c3)n(C)c2)cs1 +N#Cc1cccnc1N1CCCN(Cc2nc(N)nc(N)n2)CC1 +Cc1nc(NCc2cccc(C(N)=O)c2)c2c(C)c(C)sc2n1 +COCC(=O)NC1CCOc2ccc(C(O)C(C)C)cc21 +Cc1ccc(F)c(NC(=O)c2cc(C)n(-c3nccs3)c2C)c1 +COCCNC(=O)COc1ccc(CO)cc1Br +CCC(=O)NC1CC(=O)N(CCc2cccc(Cl)c2)C1 +COC(=O)C(NC(=O)c1oc2ccc(OC)cc2c1C)C(C)C +COc1nc(NC(=O)c2cc(C(C)C)on2)n[nH]1 +CC1CCN(S(=O)(=O)CCCOc2ccc(F)cc2)CC1 +CNS(=O)(=O)c1ccc(C(=O)Nc2cccc(Cl)c2)o1 +O=C(CN1CCOCC1)NCc1ccc(F)cc1 +Nc1ccc2c(c1)CC(=O)N2CCOc1ccc2c(c1)OCO2 +O=C1CC(=O)CC(c2ccccc2Br)C1 +NC(=O)c1cccc(CN(CC(F)(F)F)C2CCC2)c1 +COc1ccccc1CN(CCO)C(=O)NC1CCCCC1C +CC(Cn1cccn1)NC(=O)C1CC(=O)N(c2ccccc2)C1 +COc1ccccc1-n1cc(C(=O)N2CC(O)C(OC(C)C)C2)cn1 +CCOc1cc(C)ccc1CNC(=O)c1scnc1C1CC1 +CCOC(=O)c1ccc(NC(=O)c2cnc(C)cn2)cc1 +Cc1ccn2c(=NC(=O)COCC3CCCO3)[nH]nc2c1 +CC(CC#N)N(C)C(=O)c1cc(=O)[nH]c2ccc(Br)cc12 +N#Cc1cnn(-c2ccc(C(=O)NCc3ccc(F)cc3)cc2)c1N +CCCC1CN(C(=O)Nc2ccn(-c3ncccc3Cl)n2)CCO1 +NC(=O)N1CCCC(C(=O)N(Cc2ccccc2F)C2CC2)C1 +CCc1nn(CC(=O)N2CCCC2)c(=O)c2cc3sc(C)cc3n12 +FC(F)(F)COc1ccnc(OCC(F)(F)F)c1 +CCOC(=O)c1ccnc(Nc2ccc(C#N)cc2)n1 +CCCOc1ccc(C(=O)NC2CCCC2)cc1OCC +CCc1cc(=O)[nH]c(CN(C)C2CCC(OC)CC2)n1 +CC(=O)c1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1 +Cc1ccc(NC(=O)CN2CCN(C(=O)C3CCCO3)CC2)cc1F +CCSc1ccc(C(=O)Nc2ccc3ncccc3c2)cn1 +COCCc1nc(-c2cnc(C)cn2)n(C2CCCCC2)n1 +CCc1nnc(CNc2ccc(Cl)cc2C(O)c2ccccc2)o1 +Cc1cc(CNC(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)c(C)o1 +CN(Cc1ccc(F)cc1)C(=O)Cn1nccc1-c1ccncc1 +CC(=O)Nc1ccc(NCc2cccc(F)c2F)cc1 +CC(NC(=O)c1c[nH]nn1)c1ccc2c(c1)CC(=O)N2 +Cc1nnc(SCC(=O)NC(C)CCC(C)C)n1N +CC(C)Cc1nnc(NC(=O)NC2CCC3(CC2)OCCO3)s1 +CCOC(=O)N1CCN(S(=O)(=O)NC2CCCC2)CC1 +Cc1ccc(NC(=O)CN(C)S(C)(=O)=O)c2[nH]ncc12 +CCC(=O)c1cccc(S(=O)(=O)Nc2cnn(CC(C)C)c2)c1 +O=C(CNS(=O)(=O)c1ccc2c(c1)CCO2)N1CCCC1 +Cn1cc(C(=O)NCc2ccc(OCC(F)(F)F)cc2)ccc1=O +Cc1cc(CNC(=O)Nc2ccn(-c3ncccc3Cl)n2)c(C)o1 +NS(=O)(=O)c1ccc(OCCOC(=O)c2ccccn2)cc1 +CC(=O)NCCC(=O)Nc1ccc(N(C)C)cn1 +CCOc1cc2c(c(Cl)c1OC)C(CC#N)NCC2 +COc1ccc(C(=O)NC(C)c2cccc(OC(C)C)c2)nn1 +Cc1ccccc1OCC#CCNC(=O)Cc1c(C)noc1C +Cc1nc(Nc2ccc(NC(=O)C(C)C)cc2)cc(-n2ccnc2)n1 +CCc1ncc(C(=O)OCc2ccc(SC)cc2)s1 +COc1ccc(NC(=O)c2cc(OC)c(OC)cc2C)cn1 +CCSc1ccc(C(=O)NCc2nnc(C)n2C)cn1 +COc1cc(Nc2nc(C)nc3onc(C)c23)cc(OC)c1 +Cc1cc(=O)n(Cc2ccc(C#N)cc2)cc1Br +CCCc1ccc(C(=O)Nc2nc(C)cs2)cc1 +CC(C)Cn1cc[nH]c1=NC(=O)C1CC1c1ccc(F)cc1 +CCC(OC)C(=O)OCC(=O)Nc1ccc(C)cc1Cl +CC(=O)N1CCN(c2nc3c(c(=O)[nH]2)CCCC3)CC1 +Cc1ccnc(NC(=O)C2(n3cnnn3)CCCCC2)c1 +Cc1ccc(-n2c(C)c(C)c3c(NCCCO)ncnc32)cc1 +CC(C)OCCC(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1 +Cc1noc(C)c1COc1ccc(C(=O)Nc2cccc(O)c2)cc1 +Cc1ccc(CCCC(=O)NCc2cn(-c3ccccc3)nn2)s1 +CCC(CC)NC(=O)NCC(C)Cn1nc(C)cc1C +COC(=O)c1ccccc1NC(=O)c1ccc(-n2cccn2)nn1 +CCC(C)(NC(=O)CN1CCCOC1=O)c1ccccc1 +CSc1ccc(C(=O)COC(=O)c2ccco2)cc1NC(C)=O +NC(=O)NCC(=O)Nc1cccc(C#Cc2ccccc2)c1 +Cc1cccc(C2(C(=O)NCCO)CCCCC2)c1 +COc1cc(C(=O)NCC2CCOC2)cc(Cl)c1OCC(N)=O +Cc1cnn(CC(=O)Nc2ccc(NC(C)c3ccccc3)cc2)c1 +Cc1noc(C)c1CSc1nnc(C(F)(F)F)n1N +CC(C)Oc1ccc(CNC(=O)NC(C)c2ccccn2)cc1 +CNC(=O)Cn1c(C(C)(C)C)nc2c(N)cccc21 +CC(NC(=O)CCCCNC(N)=O)c1cccc2ccccc12 +CCCn1nc(-c2ccc(OC)cc2OC)cc1C(=O)N(C)CC +CCNC(=O)CC1CSc2nc(C)c(C)c(=O)n21 +CC(C)Cc1ncc2c(n1)CN(C(=O)c1cc(C3CC3)no1)C2 +O=C(OC1CCCCC1)c1ccc(-n2cncn2)cc1 +COc1ccc(OC)c2c1CN(c1ccc(C#N)cc1)CC2O +CCc1ccc(NC(C)C(=O)Nc2c(C)nn(C)c2C)cc1 +CCc1ccc(CN(C)C(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +CCNC(=O)CSc1nnnn1-c1c(C)cccc1C +O=C(NCCc1ccc(-n2cccn2)cc1)C1CC=CCC1 +Brc1ccccc1-n1nnnc1CSc1ncn[nH]1 +COC(=O)c1ccc(-c2nc(-c3ccc(C#N)cn3)no2)cc1 +C#CCOc1c(Cl)cc(C2NC(=O)c3ccccc3N2)cc1OC +CNC(C(=O)OC)c1cc(Br)ccc1F +Cc1ccc2[nH]cc(CNc3nc(=O)c(C)n[nH]3)c2c1 +CN1C(=O)CC(C(=O)Nc2cnc3ccccc3c2)C1c1cccnc1 +Cn1cccc1C1NC(N)=Nc2nc3ccccc3n21 +COc1cc(C)c(CNC(=O)c2cnc(C)nc2C)cc1C(C)C +Cc1nc(SCC(=O)NCCC#N)c2c(C)c(C)sc2n1 +Cn1cc(S(=O)(=O)NC2CCCN(S(C)(=O)=O)C2)cn1 +COC(=O)CCC(=O)NCc1ccc(C)c(F)c1 +Cc1cc(C)cc(OCCC(=O)Nc2ccccn2)c1 +COc1ccc(CC2CN(Cc3cc(C)c(C)o3)CCO2)cc1 +CCCCN(C)C(=O)NCc1ccc(S(N)(=O)=O)cc1 +COCCCNc1ncnc(Oc2ccc3ccccc3c2)c1N +COC(=O)c1ccc(CNC(=O)C(C)N2CCOCC2)cc1 +O=C(Nc1ccc(Cl)cc1)c1csc(Nc2ncccn2)n1 +CC(=O)N(C)CC(=O)N(C)Cc1nc2ccccc2[nH]1 +O=C(NCc1ccncc1)NCc1ncc(-c2ccccc2)o1 +Cc1noc(C)c1S(=O)(=O)NC1CCc2ccccc21 +CCSc1nnc(SCc2nnc(-c3cccs3)o2)s1 +CCNC(=O)Cn1cc(S(=O)(=O)N(CC)CC)ccc1=O +Cc1cc(-c2nnc3sc(-c4csnn4)nn23)n(C)n1 +C=C(C)COc1cccc(NCC(=O)N2CCOCC2)c1 +Cc1ccc(OCCNC(=O)C(C)Sc2ccccn2)cc1 +CC1Cc2cc(S(=O)(=O)NC3CCOC3C)cc(Cl)c2O1 +COc1ccc(NC(=O)NC2(c3ccccc3F)CC2)cc1OC +Cc1ccc(Cn2nnc(-c3cccs3)n2)cc1 +C=CCSc1ccccc1NCc1cccnc1 +CC(c1ccco1)N(C)C(=O)c1cc(-c2ccc(F)cc2)[nH]n1 +CN(C1CCCCC1)S(=O)(=O)N1CCN(C(=O)NC2CC2)CC1 +CC(=O)N1CCN(CCNc2nc(C)cc(C)c2C#N)CC1 +O=C(Nc1nc(-c2ccc3c(c2)OCCO3)cs1)C1CC1 +COCC(=O)N1CCN(Cc2c(Cl)ccc3cccnc23)CC1 +CC(=O)c1ccccc1NC(=O)c1cnc(C)cn1 +O=C(NCc1cccs1)c1cc2cccn2cn1 +COCCCN(C)C(=O)Nc1cccc(SC)c1 +O=C(NCc1ccccc1C(F)(F)F)c1cc2c(cn1)OCC2 +O=C(c1cnccn1)N1CCC2(CC1)CN(CC1CC1)C2=O +N#Cc1cccc(S(=O)(=O)Oc2ccccc2C#N)c1 +Cc1ccccc1-c1noc(-c2nnn(-c3ccccc3C)c2N)n1 +CCOc1cc(C)c(-c2cc(=O)[nH]c(N)n2)cc1C +CCn1nnnc1-c1cccc(C(=O)Nc2ccc(C)cc2)c1 +Nc1cccc(NC(=O)Cn2c(=O)cnc3ccccc32)c1 +COc1ccc(OC)c(C(=O)N2CCCC2C(=O)N(C)C)c1 +CC(Cc1ccccc1F)NC(=O)c1ccc(Cn2cccn2)cc1 +N#Cc1ccsc1NC(=O)CSc1ncccn1 +COCCC(=O)Nc1cccn2nc(C3CCC3)nc12 +CC(CO)CNC(=O)NC1CC(=O)N(C)C1c1ccc(Cl)cc1 +CNC(=O)c1nn(C)c2c1CC(NCc1ccccc1OC)CC2 +COc1cccc(CSc2cc(-n3nc(C)cc3C)ncn2)c1 +Cc1nc(CN(C)S(=O)(=O)c2ccccc2C#N)cs1 +Nn1c(SCCCOc2ccccc2)nnc1C(F)(F)F +Cc1cc(N)ccc1NC(=O)c1ccc(Cl)cc1O +CC(Cn1cc(Cl)cn1)C(=O)NCC1CCC1 +CC(=O)NCC1CCN(S(=O)(=O)C2CC2)CC1 +CCOC(=O)c1cc2cc(Cl)ccc2oc1=O +CCc1ccccc1N1CC(C(=O)NC(C)(C)C)CC1=O +C#CCCNS(=O)(=O)c1ccc(C(=O)OC)cc1 +CC(C)CCOCCNC(=O)C1COc2ccc(F)cc2C1 +CCn1nc(C)cc1C(=O)Nc1cc(C(C)C)n[nH]1 +O=C(Cc1c(F)cccc1F)N(Cc1ccccc1)CC1CCCO1 +Cc1nn(CCCNC(=O)C2CCCO2)c(C)c1Br +Cc1ccnc2nc(C(=O)N(C)Cc3ccc4c(c3)OCO4)nn12 +CCCNC(=O)CCNc1cc(C)nc2nc(-c3cccnc3)nn12 +COc1cc(C)c(C(=O)Nc2cccc(C(N)=O)c2)cc1OC +Cc1ccc2nc(COCC(=O)NCc3cnc(C)cn3)[nH]c2c1 +CCC(C#N)Oc1cccc(CNC(=O)COC)c1 +CCCCN(Cc1cc2ccccc2[nH]c1=O)C(=O)CCC +COc1ccc(F)cc1NC(=O)c1cc(N2CCCC2=O)ccc1F +CCCc1nc2c(OC)c(OC)c(OC)cc2c(=O)[nH]1 +O=C(NC1CCCC(O)C1)NC(c1ccccc1)c1ccccc1 +CCCOc1ccc(CNC(=O)C2CCCCN2C(=O)CC)cc1 +Cc1sc(NC(=O)Cc2ccccc2OC(C)C)c(C(N)=O)c1C +Cc1cc(C(=O)Nc2ccc3nc(N4CCCC4)sc3c2)on1 +COc1ccc(C2(Cc3cccc(C)c3)NC(N)=NC2=O)cc1OC +CC(C)C(NC(=O)c1cc(-c2ccccn2)n[nH]1)c1cccs1 +CC(C)c1nnc2n1CC(Nc1ncnc3ccccc13)CC2 +Cc1cc(NC(=O)COc2cccc3cccnc23)n(C(C)(C)C)n1 +O=C(CNC(=O)NCCC(=O)N1CCCCC1)NC1CCCCC1 +CC(=O)c1sc(N(C(=O)C2CC2)C2CC2)nc1C +COC(=O)C(C)(C)NCc1ccc(OC)cc1F +COc1ccc2cc(NC(=O)NCc3cccs3)n(C)c2c1 +Brc1cccc2c1CCNC2c1ncccn1 +O=C(NCCc1ccccn1)c1[nH]nc2c1CCC2 +O=C(COC(=O)c1cc(F)ccc1Cl)NCc1ccc(F)cc1 +O=C(Nc1ccc(-n2ncc3ccccc32)cc1)c1ccon1 +O=C(CCNC(=O)c1cc[nH]n1)NCc1cccnc1 +CCC(NC(=O)Nc1ccnn1C(C)C)c1cccc(Cl)c1 +CCn1c(CCNC(=O)c2c(F)cccc2F)nc2cccnc21 +Cc1nc(-c2c[nH]c(C(=O)N3CCNC(=O)C3)c2)cs1 +CCCC1CN(C(=O)c2cnn(-c3ccccc3)c2)CCO1 +Cc1cc(C)cc(OCCNC(=O)NCC(=O)Nc2cccnc2)c1 +CC(C)C(=O)N1CCc2nc(NC(=O)c3ccco3)sc2C1 +CS(=O)(=O)c1ccc2nc(NC(=O)c3ccc(=O)[nH]c3)sc2c1 +Cc1cc(CNC(=O)COc2ccc3c(c2)CCC3)ccc1F +COCCOC1CCN(c2ncccc2F)CC1 +O=C(CNC(=O)OCc1ccccc1)Nc1ccc2oc(=O)[nH]c2c1 +COc1cc(CNC(=O)C(C)Sc2ccccn2)ccn1 +Cc1ccc(OCc2nc(C(=O)NCc3ccccn3)cs2)cc1 +CCOC(C)C(=O)Nc1c(C(=O)N2CCOCC2)oc2ccccc12 +C=CCn1nnnc1SCc1noc(-c2ccsc2)n1 +CC(C)(C)c1n[nH]cc1CN1CCOC(c2cccc(O)c2)C1 +O=c1nc2n(Cc3ccco3)c3nc4ccccc4cc3cc-2c(=O)[nH]1 +OCCn1c(Cc2ccccc2)nc2cc3c(cc21)OCCO3 +COc1cc(-c2nc(C)cs2)cc(OC)c1OC +O=C(c1cnccn1)N1CCc2c(nc(-c3ccccn3)[nH]c2=O)C1 +CN(CC(=O)N(Cc1ccccc1)C1CC1)c1ncnc2[nH]cnc12 +Cc1ccc(NC(=O)N(C)Cc2ccncc2)c(Cl)c1 +COC(=O)c1cccc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)c1 +CCC(C)c1noc(C2CCCN(C(=O)Cc3cccs3)C2)n1 +Cc1cc(C(=O)Oc2cccc(C(=O)N(C)C)c2)c(C)o1 +COC(=O)c1ccccc1SCc1nnc(SC)s1 +CCn1c(-c2cc(NC(C)=O)[nH]n2)cc2c(OC)cccc21 +CC1C(=O)Nc2c1cc(F)cc2C(O)c1ccccc1Cl +NC(=O)c1ccc(NC(=O)c2ccc(=O)n(Cc3ccccc3)n2)cc1 +CCOC(=O)c1cnc(SC)n1-c1ccc(F)cc1 +CCC(c1ccncc1)N(C)C(=O)c1c[nH]c2cccc(F)c12 +COc1cc(NS(=O)(=O)c2cn(C)nc2C)cc(OC)c1OC +O=C(Cc1ccc2c(c1)OCCCO2)c1ccc(O)cc1O +COCCCn1c(SCCO)nc2sc3c(c2c1=O)CCC3 +Cc1[nH]ccc1C(=O)NCc1ccnc(OC2CCC2)c1 +CCOC(=O)c1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +COc1ccc(C(C)NS(=O)(=O)CCc2ccccc2)cc1F +CCOc1cc(-c2cc(-c3ccc[nH]3)nc(N)c2C#N)ccc1O +CCN(CC)C(=O)C1CCN(C(=O)C(OC)c2ccccc2)CC1 +COc1ccc(F)cc1-c1cn2nc(N)nc2cc1C +CC(OCc1ccccc1)C(=O)NCC(=O)Nc1cccc(F)c1 +CCCN(Cc1nnc(-c2ccco2)o1)C(=O)c1ccccn1 +Cc1cccc(CN(C(=O)CC2OC(=O)c3ccccc32)C2CC2)c1 +Cc1ccc(NC(=O)CCCc2nc3ccccc3c(=O)[nH]2)cc1F +CCOCc1ccccc1CNC(=O)Nc1cc(C(F)(F)F)no1 +COc1cccc(C(O)C(=O)NC2CCC(C(F)(F)F)CC2)c1 +COCCN1CCC2CN(C(=O)c3cnccn3)CC2C1=O +O=c1[nH]c(CN2CCCC2c2ccccc2)nc2ccccc12 +O=C(Cn1nnc2sc(-c3ccccc3)cc2c1=O)N1CCCC1 +Cc1nc(CNC(=O)Nc2nnc(C3CCCCC3)s2)oc1C +NC(=O)C1CCCCN1C(=O)Cn1cnc(N)n1 +Cc1nnc(SCCC(=O)Nc2cc(Cl)ccc2Cl)n1N +Nc1nc2c(cc1C(=O)NCCc1ccc(F)cc1)CCC2 +CC(c1ccccc1)n1nnc(CO)c1C(F)(F)F +CCOC(=O)Cn1c(=O)ccc2c(C)cc(C)nc21 +OC(CN1CCN(c2ccccc2)CC1)c1ccc2cc[nH]c2c1 +Cc1[nH]c(SCC(=O)NCC(=O)N(C)C)nc1Cc1ccccc1 +CN(Cc1cc(F)ccc1C#N)C1(C(N)=O)CCCC1 +COc1ncccc1CNC(=O)NCC(O)c1ccc(F)cc1 +COc1cc(NC(=O)N(C)C(C)c2ccccn2)cc(OC)c1 +O=C(Nc1cccc2cn[nH]c12)c1cccc(OCC(F)F)n1 +O=S(=O)(Nc1ccccc1)c1ccc(CCO)cc1 +Cc1[nH]ccc1C(=O)Nc1ccc(N2CCCCC2)cc1C(N)=O +COc1cc(C(C)C)ccc1-c1cc(C)nc(N)n1 +CS(=O)(=O)NC1CCCc2nc(-c3ccccc3)ncc21 +CC(C)N(C(=O)CN1CCN(c2ccccc2Cl)CC1)C(C)C +O=C(Nc1ccccc1)N1CCCC(C(=O)N2CCCCCC2)C1 +Cc1nc2ccc(NC(=O)c3cnn(-c4ccccc4)n3)cc2o1 +COc1cccc(C(=O)NCCC(=O)NCc2ccccc2)c1F +CCC1CN(C(=O)c2nc(C)ncc2Cl)CC1N1CCOCC1 +CC(O)(CNC(=O)Nc1ccc2c(c1)OCO2)c1cccs1 +Cc1cc(C(=O)N2CC(C(=O)NCCc3cccs3)C2)no1 +CC1CCC(NC(=O)c2sccc2Br)CC1 +Cn1cc(C(=O)Nc2ccc3c(c2)COC3)c(C(F)(F)F)n1 +CCCC(=O)N1Cc2ccc(C(O)C3CCCO3)cc2C1 +CNC(=O)COC(=O)CCSc1ccc(C)cc1 +Cc1cc(C(=O)NCCN2CCCS2(=O)=O)nn1-c1ccccc1 +N#CCc1ccc(NCc2cnc(C3CC3)s2)cc1 +COC(CNC(=O)c1ccno1)c1ccc(C)s1 +CC(C)CNC(=O)CSc1nc(-c2ccccc2)n[nH]1 +COCc1ccccc1C(=O)Oc1ccc2c(c1)OCO2 +CCc1cnc(NC(=O)Nc2c(C)n[nH]c2C)s1 +Cc1ccc(CC(=O)N2CCN(CC(O)c3ccccc3)CC2)cn1 +COc1ccc(Cc2cc(C)[nH]c(=O)c2C#N)cc1OC +CCC(NCc1ccco1)C(O)c1cc(F)ccc1F +CCN(CC)C(=O)Cc1ccc(OCc2nnnn2C)cc1 +COc1ccc(OCCC(=O)NCc2ccco2)cc1 +Cc1noc(C(NC(=O)c2ccc3[nH]cnc3c2)C(C)C)n1 +COc1ccccc1CNC(=O)c1ccccc1C +Cc1cc(C(C)NC(=O)Nc2ccc(-n3cnnn3)c(C)c2)c(C)o1 +CC(O)C1CCN(C(=O)NCCC2Cc3ccccc3C2)C1 +O=C1CCN(C(=O)C2CC3C=CC2C3)CCN1Cc1ccccc1F +CC(=O)NC(C(=O)NCc1c(C)nn(-c2ccccc2)c1C)C(C)C +O=C(NC1CCC(O)CC1)c1ccc2c(c1)CCO2 +Cc1c[nH]nc1C1CCCCN1C(=O)Cn1cccn1 +CN(Cc1cc(Br)cn1C)C(=O)c1cc(F)ccc1O +O=C(OCc1ccccc1)N1CCC(F)C(O)C1 +CCc1ccccc1NC(=O)Cn1cc(Br)ccc1=O +CCCC1CCc2c(n(C)c3ccccc3c2=O)O1 +CCCC(=O)NCc1ccc(C(=O)N2CCNC(=O)C2)cc1 +CCN(C(=O)c1cc(OC)cc(OC)c1)C(C)c1ccc(C#N)cc1 +COc1cccc(Cc2cnc(NC(=O)C3CCC(=O)NC3)s2)c1 +CC(C)c1noc(CCNC(=O)NCC(F)(F)F)n1 +COC(=O)c1ccc(C(=O)Nc2cccc(Cl)c2N(C)C)s1 +O=C(c1cccnc1)N1CCC(c2cccc(C(F)(F)F)c2)C1 +Cc1noc(C2CC3OCCC3N(Cc3scnc3C)C2)n1 +COc1ccccc1OCCC(=O)NC(C)(C)CO +COCCCN(C)C(=O)Nc1ccc(Br)cc1C +C#CCN1CCN(Cc2nc(-c3ccc(F)cc3)no2)CC1 +Cn1c(SCC2CCCO2)nnc1-c1ccco1 +COC(=O)CCC(=O)c1cc(C(C)C)ccc1OC +CCC(C)C(NC(=O)Cc1coc2cc3c(cc12)CCC3)C(N)=O +C#Cc1cccc(NCc2cc(Cl)cc3c2OCOC3)c1 +COCC(O)CN(C)C(=O)NCc1nncn1-c1ccccc1 +O=C(c1ccncc1)N1CCN(C(=O)C2CCCO2)CC1 +CCCn1c(CCCO)nc2ccc(Cl)cc21 +Cc1cnn(C2CCCN(C(=O)c3ccc4c(c3)NC(=O)CO4)C2)c1 +CC(NC(=O)CC1CCCO1)c1ccc(Cl)c(Cl)c1 +Cc1csc(S(=O)Cc2ncc(-c3cccs3)o2)n1 +Cc1noc(C)c1COc1ccc(-c2nnc3ccc(N)cn23)cc1 +CC(C)Cn1cc(NC(=O)Cc2cccc(F)c2F)cn1 +CC(NC(=O)COc1ccc(Br)cc1)c1ccncc1 +O=C1CCN(CCNS(=O)(=O)c2ccccc2)c2ccccc2N1 +Cc1nc(C)c(COC(=O)c2ccc3c(c2)[nH]c(=O)n3C)s1 +CC(=O)c1ccc(OCC(=O)Nc2ncc(C)s2)cc1 +Cc1noc(C)c1CCC(=O)Nc1cccc2c1CCCC2 +CCN(C)C(C(=O)Nc1cccc(C(=O)NC)c1)c1ccccc1 +Cc1ccc2c(c1)N(C(=O)c1cccc3ccc(C)nc13)CC2 +Cc1c(C(=O)N2CCc3sccc3C2)[nH]c2c1C(=O)CCC2 +COc1cccc(OC)c1-c1nc(C)c(C(C)=O)s1 +CC1CCN(c2ccc(S(=O)(=O)N3CCCC3)cc2N)CC1 +CCCN(CC1CCCCO1)C(=O)Nc1ccncc1C +COC(=O)Nc1ccc(NC(C)C(=O)N(C(C)C)C(C)C)cc1 +CCNc1nnc(-c2cnc(C3CC3)s2)s1 +COCCCNS(=O)(=O)c1ccc2c(c1)NCC(C)(C)O2 +CC(O)CN1CCN(C(=O)c2cccn2Cc2ccncc2)CC1 +Cc1nn2c(CNC(=O)c3ccccc3F)c(C)nc2s1 +CN(C(=O)CCNC(=O)C(C)(C)C)c1ccccc1 +Cn1c(C(C#N)C(=O)c2ccc3c(c2)CCO3)nc2ccccc21 +O=C(NCCc1cccs1)NC1CC1c1ccccc1 +CCc1nnc(NC(=O)c2cn3c(C)cccc3n2)s1 +Cc1ccc(C#N)c(SCc2cc3cc(O)ccc3o2)n1 +Cc1nc(-c2ccsc2)ccc1C(=O)N=c1[nH]nc2ccccn12 +O=C(Nc1cc(Cl)cc(Cl)c1)C1CCOCC1 +CN1CCC(C(=O)Nc2ncn(Cc3ccccc3)n2)CC1=O +CCOC(=O)CN(C)C(=O)c1cc(Cl)cc(Cl)c1 +Cc1nc(NCCCn2ccnc2)c2c3c(sc2n1)CCCC3 +COc1ccc(-c2ccc(N(C)C)nc2)c(OC)n1 +CCc1nnc(CN(C)c2cc(C3CC3)ncn2)o1 +COc1nc(NC(=O)c2sc(C)nc2CC(C)C)n[nH]1 +COC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2F)cc1 +Nc1c(C(=O)NCc2cccs2)nnn1Cc1ccccc1Cl +Cc1nn(C)c2nc(N3CCN(c4cnccn4)CC3)sc12 +CC(NC(=O)C1COc2ccccc2O1)C1CCCOC1 +COC1CCCCC1OC(=O)CCc1cnn(C)c1 +COc1ccc(CSc2nc(N)cc(=O)[nH]2)cc1 +N#Cc1ccccc1CN1C(=O)c2ccccc2S1(=O)=O +O=C(NCCC1=CCCCC1)c1ccc2c(c1)OCCO2 +COc1ncnc(OC)c1CNCc1nncn1C +COc1cccc(CC2CN(CCCn3nnnc3C)CCO2)c1 +N#Cc1nnn(-c2ccc(Cl)cc2)c1C(F)(F)F +COC(=O)c1ccccc1Cn1ccnc1Cc1ccccn1 +CCOc1ccc(NC(=O)N2CCC(N3CCOC(C)C3)CC2)cc1 +CCCOc1ccc(OCC(=O)Nc2cccn(C)c2=O)cc1 +Nc1ncc(Br)cc1S(=O)(=O)NCc1cccnc1 +CC(NC(=O)c1cc2c(=O)n3ccccc3nc2n1C)c1ccccc1 +COc1ccc(C(=O)CSc2cc(N3CCOCC3)ncn2)cc1 +CCCn1nc(-c2ccc3ccccc3c2)cc(N)c1=O +CC(=O)c1ccc(NC(=O)C(C)OCC(F)(F)F)cc1C +Cc1csc(NC(=O)Nc2cc(F)ccc2F)n1 +C#Cc1cccc(NC(=O)CN(C)C(=O)CCc2ccsc2)c1 +Cc1ccc(-c2nc(CNC(=O)C3CC3)[nH]c2-c2ccccn2)cc1 +CCC(=O)N1CCC(Oc2nc3c(F)cccc3s2)CC1 +CCOC(=O)C1=C(C)Nc2ncnn2C1c1ccc(O)cc1 +CC(C)n1nccc1NC(=O)c1cc(S(C)(=O)=O)ccc1Cl +Cc1nc(CNC(=O)Nc2cc(F)ccc2OC(F)F)c(C)s1 +CNC(=O)c1ccc(Cl)cc1NCC(=O)NC1CCCCC1 +CCOC(=O)c1c(NC(=O)c2ccncc2)sc2c1CCC(C)C2 +CN(C(=O)COc1nnc2ccccn12)c1ccccc1 +CC(=O)NC(c1ccc(Cl)cc1)n1nnc2ccccc21 +CCOC(=O)c1c(C)[nH]c(C)c1S(=O)(=O)Nc1ccccc1 +Cc1csc(=O)n1CCC(=O)NCc1ccnc(OC2CCC2)c1 +COC(=O)N1CCCC1C(=O)NCCOc1cccc(OC)c1 +O=C(CCC(=O)c1ccc(F)cc1)NCc1nnc2ccccn12 +O=C(Cn1c(=O)oc2ccccc21)N1CCOc2ccc(F)cc21 +Cc1ccc(NC(=O)NCc2ccc3c(c2)CCO3)cc1 +Cc1ccc(N(Cc2ccco2)C(=O)CNC(=O)c2ccccc2)cc1 +CN(C)C(=O)c1cccc(NC(=O)CN2CCCc3ccccc32)c1 +CC(OC(=O)c1ccc(-c2ccccc2F)o1)C(N)=O +CC(C)N(CCc1nccs1)C(=O)NCC(C)(C)c1ccncc1 +CCc1noc(CN(C)Cc2cc(C(N)=O)cs2)n1 +O=C(CC1CCCCC1)NCCn1ccnc1-c1ncccn1 +CS(=O)(=O)NCCCNC(=O)Cc1cccs1 +C=C(C)CN(CC)C(=O)Cn1cnc2sc3c(c2c1=O)CCC3 +O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc1ccon1 +C#CCNC(=O)c1cccc(NS(=O)(=O)c2cc(C)ccc2C)c1 +Cc1csc(=O)n1CC(=O)NCCOCC(F)(F)F +Cc1ccccc1CC(=O)NC1CCN(c2ccc(F)cc2)C1=O +O=C(NCc1ccc2ccccc2c1)Nc1ccncc1 +COC(=O)c1cc(OC(C)C)c(OC(C)C)cc1Cl +COCC(=O)Nc1c(C)c(C(C)(C)C)nn1-c1ccccc1 +CC(NC(=O)NC1CCN(S(C)(=O)=O)CC1)C1CCCO1 +CCOCCCn1cnc2c(F)cc(Br)cc2c1=O +CNC(=O)c1cccc(NCC(=O)Nc2ccc(C)cc2)c1C +COC(=O)c1cc(NC2CCN(CC(F)(F)F)C2=O)ccc1C +Cc1cccc(-n2nnnc2SCCOC(C)(C)C)c1 +c1ccc2oc(CSc3nnc(-c4ccncc4)n3C3CC3)nc2c1 +CC(=O)c1cccc(NC(=O)COc2ncnc3oc(C)c(C)c23)c1 +CCc1nnc(NC(=O)Nc2ccccc2OC)s1 +CCc1nc(C2CCCN(c3c(F)cc(C#N)cc3F)C2)no1 +CCCCNC(=O)NC1CCN(c2c(F)cccc2F)C1=O +Cc1ncsc1C(=O)NCC(C)c1nc(-c2ccccc2)no1 +CCNC(=O)CN(Cc1ccccc1)S(=O)(=O)c1ccc(C)cc1 +CCOc1ccc(NC(=O)c2ccc(Cl)cc2N)cc1 +O=C1CN(C(=O)Cc2cccc(Br)c2)CCN1 +CC(=O)N1CCC(C(=O)Nc2ccc(C)cn2)CC1 +NC(=O)c1csc(C(=O)Nc2ccc(OCC3CCCO3)cc2)c1 +CCCN(Cc1ccccc1)C(=O)Nc1nc(C)cs1 +O=C(NCCO)c1ccc(CSc2nc3ccccc3s2)cc1 +Cc1nc2ccc(NC(=O)CCn3ncc4c3CCCC4)cc2s1 +O=C(OC1CCCCC1=O)c1c2c(nc3ccccc13)CCC2 +O=C(Nc1ccc(N2CCCS2(=O)=O)cc1)c1ccsc1 +Cc1n[nH]c(C2CN(C(=O)COC3CCCC(C)C3)CCO2)n1 +O=S(=O)(c1cccc(F)c1)N1CCCC(c2cnccn2)C1 +CC(=O)N1CC2CCC(C1)N(S(=O)(=O)c1cccc(C)c1)C2 +CCOc1ccc(C(=O)NC2(C#N)CCCC2)cc1 +O=C(NCc1cccs1)C1CC(O)CN1C(=O)Nc1ccccc1 +CC(=O)c1cccc(OCC(=O)N2c3ccccc3CC2C)c1 +COc1cc(C(=O)NC(C)c2c(C)noc2C)cc(OC)c1OC +Cc1cccc(C(=O)NC(C)c2nnc3n2CCCCC3)n1 +CC1CN(C(=O)Nc2ccc3oc(C4CC4)nc3c2)CCO1 +Cc1c(C(=O)Nc2cn[nH]c2)oc2ccc(Br)cc12 +COCC(NC(=O)Cn1ccc2ccccc21)C(N)=O +CC(=O)c1ccc(OCC(=O)c2ccc3c(c2)CCO3)cc1F +CCCC(=O)Nc1c(C(=O)Nc2ccc(F)cc2)oc2cccnc12 +Cc1nc(-c2ccc(NC(=O)N3CCc4ccccc43)cc2)no1 +CC(C)CCN(C)C(=O)c1csc2c1CCCC2 +CCCNC(=O)c1nc2ccccn2c1-c1ccc(F)cc1 +CCOC(=O)CNC(=O)C(c1ccccc1)c1ccccc1 +O=C(NCc1ccc(-n2cccn2)cc1)c1coc(-c2ccccc2)n1 +CCNc1oc(-c2ccc(OC)c(OC)c2)nc1C#N +CC(NC(=O)CSc1ncc2ccccn12)c1ccccc1 +CC(C)c1nn(C)cc1C1NC(N)=Nc2nc3ccccc3n21 +COC(=O)N1CCC(NC(=O)c2sccc2Br)CC1 +COC(=O)c1ccccc1NC(=O)c1cccc2c1SCCC2=O +Cn1cc(N2CCC(NC(=O)NC(c3nccs3)C3CC3)C2)cn1 +CCOC(=O)C(C)(C)N(C)Cc1nc2c(s1)CC(C)CC2 +COc1ccccc1C(C)NC(=O)Cc1n[nH]c(=O)c2ccccc12 +Cc1nc(C)c(CC(=O)N(C)C(C)c2ccco2)c(=O)[nH]1 +COC(=O)c1cccc(C(=O)N(C)CCc2cccc3ccccc23)n1 +Cc1ccccc1C(C#N)CC(=O)Nc1ccc(F)cc1 +Cc1ccc(CN2CCN(C(=O)c3ccccc3O)C(C)C2=O)cc1 +O=C(CCCc1cn[nH]c1)N1CCC2(CCC(=O)N(CCO)C2)CC1 +COc1cc(C)cc(C)c1-c1cc(C(C)=O)c(C)n1C +Cc1ncc(CNC(=O)C2(c3cccc(Cl)c3)CCC2)s1 +COc1ccc(Nc2ncc3c(n2)CC(C)CC3=O)cc1 +CN(c1cccnc1N1CCCC1)S(=O)(=O)c1cccs1 +Cc1c(C(=O)Cn2cncn2)cnn1-c1ccccc1 +CCOc1cc(C#N)ccc1OS(=O)(=O)c1ccc(F)c(C)c1 +CNC(=O)c1cccc(CCNC(=O)Nc2ccc3c(c2)COC3)c1 +O=C(CNc1ccc(F)cc1)N(Cc1ccccc1)C1CC1 +Cc1noc(C)c1C(C)C(=O)N1CCCC1CC(=O)c1ccccc1 +Cc1nccc(C2CCCN(Cc3cnn(C)c3)C2)n1 +CCC(Cc1ccccc1)N(C)Cc1ccnn1C +COC(=O)c1ccc2oc(=O)c(-c3nc(-c4cccnc4)no3)cc2c1 +COCCOc1ccc(S(=O)(=O)Nc2c(C)cccc2C)cc1 +Cc1cc(C(=O)NCC(=O)Nc2ccc(F)c(F)c2F)c(C)o1 +COCc1csc(NC(=O)CCN2C(=O)CCc3ccccc32)n1 +Cc1ccc(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)c(=O)[nH]1 +COCC(=O)N1CCc2nnc(CNS(C)(=O)=O)n2CC1 +CCOC(=O)N1CCC(NC(=O)NCCc2cccc(C)c2)CC1 +COc1cccc(CNC(=O)c2cccnc2N(C)C)c1 +CCNS(=O)(=O)c1cc(-c2ccc(=O)n(C)n2)sc1C +CC(OC(=O)c1ccc(-n2cnnn2)cc1)C(N)=O +COc1ccc(CCC(=O)Nc2c(C)ccc(N)c2C)cc1 +NC(=O)c1cccc(OC(=O)C=C2CCCCC2)c1 +CCOC(=O)CSc1nnc2n(CC)c(=O)c3ccccc3n12 +COc1ccc(F)cc1NC(=O)c1ccc(S(C)=O)cc1 +COc1ccc(S(=O)(=O)Nc2cccc(O)c2)c2ccccc12 +CC(C)CCNC(=O)NCc1ccc(CN2CC(C)OC(C)C2)cc1 +CCc1onc(C)c1NC(=O)N(C)CC1CCCC1O +CC(C(=O)Nc1ccc(CN2CCOCC2)c(Cl)c1)n1cncn1 +Nc1nonc1-c1nc(Cc2cccc(F)c2)no1 +CC(=O)c1c(C)nn(CC(=O)N2CC(c3ccncc3)C2)c1C +COc1ccc(Cl)cc1NC(=O)c1cn[nH]c1 +COc1ccc(OCc2nc(-c3ccc4c(c3)ncn4C)no2)cc1 +COC(=O)Nc1cccc(NCc2nnc(C(C)(C)C)o2)c1 +CCc1onc(C)c1C1CCCN1C(=O)c1ccccc1F +CC(C)c1cc(C(=O)Nc2nc3c(s2)CCc2c-3cnn2C)on1 +Cc1cc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)c(C)n1C1CC1 +COCCn1c(=O)n(CC(=O)NC2CCCC2)c2cccnc21 +CC1CC1CNC(=O)c1ccc(OCC(N)=O)cc1 +COc1ccc(C)cc1-n1ccnc1-c1ncc[nH]1 +Cc1cc(C)nc(NC(=O)C2CSc3nccc(=O)n3C2)n1 +CCOC(=O)c1[nH]c(C)c(CCC(=O)N2CCOCC2)c1C +CSc1ccccc1NCc1nc(C)cs1 +O=C(NC1CC1)N1CCC(CN2CCOCC2)CC1 +COC(=O)CNC(=O)C(C)Sc1nc(-c2ccccc2)cn1N +CCCCCC(C)(C)NC(=O)CN1CCOCC1 +CCOC(=O)C=C(C)Nn1c(N)nnc(C)c1=O +Cc1cc(NC(=O)c2cn(-c3cccc(Cl)c3F)nn2)c[nH]c1=O +COC(=O)CCC(=O)Nc1c(C)cccc1Cl +CC(C)CNS(=O)(=O)c1ccc(C#CCO)cc1Cl +COCCN(c1cc(N)cc(F)c1)C(C)COC +O=C(CSc1nnnn1-c1ccccc1)N1CCCCCC1 +COCCOc1ncccc1NC(=O)c1ccc(C)[nH]c1=O +CCn1nc(C(=O)Nc2cccc3cccnc23)c2ccccc2c1=O +COCCNC(=O)N1CCC(Oc2cnc3ccccc3n2)CC1 +CCOC(=O)C1CCCN(C(=O)CCc2ccc(F)cc2)C1 +CCOc1c(Cl)cc(C(=O)NC(C)CC)cc1OC +Cc1nc(CN(C)C(=O)NCc2cccs2)cs1 +CC(O)c1cccc(NC(=O)NCc2ccsc2)c1 +CN(C)C(=O)c1ccc(Cl)c(NC(=O)NCc2cscn2)c1 +O=C(NCCCCN1CCOCC1)c1ccc(Cl)c2cccnc12 +O=C(c1cccc(O)c1)N1CCCC2(CCC(=O)N(C3CC3)C2)C1 +Cc1c(NCC(=O)NC(C)C(C)C)cccc1C(N)=O +Cc1cc(C)cc(C(=O)Nc2ccnn2C(C)C)c1 +CC(NC(=O)C(C)NS(C)(=O)=O)C(=O)NC1CCCC1 +Cc1c(Br)cccc1COC(=O)c1ccc(C(N)=O)cn1 +COc1cc(OC)cc(C(=O)Nc2nnc3n2CCS3)c1 +Cc1cc(C)c(CNC(=O)CN2CCc3ccccc32)c(=O)[nH]1 +N#Cc1c(N2CCOCC2)nn2cc(Br)cnc12 +CCn1ccc(C(=O)N2CCC(OCc3cccnc3)CC2)cc1=O +NC(=O)C1CCCN(c2nc(-c3cccnc3)nc3ccccc23)C1 +O=C(Nc1ccc(-c2nnnn2C2CC2)cc1)NC1CC1 +O=C(Nc1cccc(C(=O)N2CCCCC2)c1)c1cccs1 +C#CCN1CCC(C(=O)NCCNc2nc3ccccc3s2)CC1 +CC(O)c1nc2cccnc2n1-c1ccccc1N +COC1COC2(CCN(C(=O)CC3Cc4ccccc4C3)CC2)C1 +Cc1cnc(NC(=O)CSc2ccccc2C)s1 +Cc1cc(C)n(-c2ccc(C(=O)NC(C)CO)cn2)n1 +COc1cn(C)c(C(=O)NCCc2ccccc2)cc1=O +Cc1cccc(C)c1NC(=O)c1n[nH]nc1Nc1ccc(F)cc1 +CCN(CC)c1onc(-c2ccccc2)c1CN(C(C)=O)C(C)C +Cn1ccnc1C(NC(=O)NC1CC1)c1ccc(F)cc1 +COC(=O)Cc1c(C)nc(SCc2ccccc2)[nH]c1=O +CSc1cccc(NC(=O)Cc2csc(NC(C)=O)n2)c1 +O=C(c1c[nH]c2ccc(Cl)cc2c1=O)N1CCCC1 +CC(C)Cc1noc(Cn2nnc(-c3ccsc3)n2)n1 +CCNC(=O)CNC(=O)NCCc1c(Cl)cccc1Cl +COCCCn1ccc(NC2CCN(c3sccc3C#N)C2=O)n1 +CCOC(=O)C(O)(c1cc(F)cc(F)c1)C(F)(F)F +O=C(NCc1nc(-c2cccc(Cl)c2)no1)C1COCCO1 +CCC(C)n1ncc(C(=O)NCC(C)N2CCOCC2C)c1C1CC1 +Cc1nnc(SCC(=O)N(CCC#N)c2ccccc2)n1N +CSc1cccc(CN(C)C(=O)c2cnn3cc(C)cnc23)c1 +CCN(Cc1ccccc1)C(=O)c1ccc(N(C)C)nc1 +Cc1ccc(NC(=O)N(Cc2ccco2)CC2CCCO2)cc1 +Cc1ccc(C(=O)c2ccc3c(c2)OCCO3)cc1N +CCC1CCC(NC(=O)NCCNS(=O)(=O)CC)CC1 +O=C(CC1(CC(=O)N2CCOCC2)CCCC1)NCc1ccccc1 +CC(C)CC(NC(=O)NCCO)c1ccccc1 +COC(=O)C(C(C)C)N1CCN(C(=O)OC(C)(C)C)C(C)C1 +COc1cc(CNC(=O)NC2CCc3c(F)cccc32)ccn1 +CC(=O)NC(C)C(=O)Nc1ccccc1-c1nc(-c2ccccc2)n[nH]1 +O=c1[nH]c2ccccc2cc1-c1noc(-c2ccco2)n1 +Cn1cc(CCCC(=O)NCCc2nccs2)c2ccccc21 +CC(=O)Nc1cccc(C(=O)N(C)c2cccc3ncccc23)c1 +N#Cc1ccnc(Nc2nc3ccccc3s2)c1 +CN(CCc1ccc(F)cc1)C(=O)NCC1CCOC1 +COc1cc(NCC(=O)N(C)C)c(OC)cc1C +N#Cc1ccc(CN2CCOC3CCCCC32)c(F)c1 +Cc1ccc(-c2nc(CC(=O)N(C)Cc3cccnc3)cs2)cc1 +CC(C)Cc1cc(CNC(=O)c2cc3ccccc3oc2=O)no1 +CCCCNC(=O)C1CCCN(c2nc3nc[nH]c(=O)c3s2)C1 +Cc1ccc(C(=O)NCC(=O)N2CCn3c2nc2ccccc23)cc1C +Cc1cc(NC(=O)COc2ccc3ncccc3c2)no1 +Cc1ccccc1CS(=O)(=O)c1nncn1C +COc1cc(OC)c2[nH]c(-c3cnc(-c4ncccn4)s3)nc2c1 +CCOc1nnc(CSc2ccccn2)s1 +CCN(Cc1ccccn1)Cc1cnc2c(C)cccn12 +CCOc1ncccc1CN(C)S(=O)(=O)c1c[nH]cn1 +O=C(Nc1ccc(CNC(=O)C2CC3C=CC2C3)cc1)c1cccnc1 +CN(C)c1nc(N(C)C)n(C(=O)c2ccc(Cl)cc2)n1 +O=C(CSc1nncn1-c1ccccc1)N1CCCC1 +COc1cccc(CCN2CCCCS2(=O)=O)c1 +CCCCOc1ccc(C(N)C(F)(F)F)cc1OC +Nc1c(C(=O)Nc2ccccc2OC(F)F)sc2ncccc12 +Cc1noc(-c2ccc(S(=O)(=O)N3CCCC3)s2)c1C +N#Cc1ccc(OCC(O)Cn2nnnc2-c2ccccn2)cc1 +N#Cc1ccc(CN2CCN(C(=O)c3c(F)cccc3Cl)CC2)o1 +CNC(=O)COc1cccc(NC(=O)c2cccc3c2ccn3C)c1 +COCCN(CCC#N)c1cccc(Cl)c1CO +CC(C)CNC(=O)c1[nH]cnc1C(=O)NC1CCCCC1 +CCOC(=O)C(C)Sc1nnc(NC(=O)c2cc(C)on2)s1 +Cc1cc2[nH]c(CN3CCOC(CCCC(C)C)C3)cc(=O)n2n1 +Cc1ccc(OCCCn2nnc(CO)c2C)cc1 +COc1ccc(-c2nc3ccc(OC(C)=O)cc3c(=O)o2)cc1OC +O=C(NC1CC1c1ccccc1F)c1ccc(OCC(F)F)nc1 +c1ccc(-c2cc(N3CCOCC3)nc(-c3cccnc3)n2)nc1 +COc1ccc(NC(=O)N2CCN3CCNC(=O)C3C2)cc1OC +O=C(c1ccc(F)cc1)N1CCN(Cc2ccccc2)CC1 +CCn1c2ccccc2n2c(-c3cc(C)nn3C)nnc12 +CSc1nsc(SCCC(=O)N2CCCCCC2)n1 +O=C(NCCc1nc(-c2ccccc2)n[nH]1)c1ccncc1Cl +C=CCn1cnnc1SCC(=O)c1cccc(OC)c1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)c2ccc(=O)n(C)c2)c1 +Cc1ccc(NC(=O)c2cccnc2N(C)C)c(Cl)c1 +CCC(NC(=O)c1csc(S(N)(=O)=O)c1)C(C)C +CCCOC(=O)c1ccc(-n2nnc(C#N)c2CCC)cc1 +Cn1nccc1-c1nc(Cn2cnc3ccccc3c2=O)no1 +COc1cccc2cc(C(=O)NCc3nc(C)no3)c(=O)oc12 +CCn1ncc(NC(=O)Cn2cc(-c3nc(C)cc(NC)n3)cn2)n1 +Cc1cc(C(=O)NC(C)c2cc(F)c(Cl)cc2Cl)no1 +Cc1ccc(C(N)=O)cc1NC(=O)CNC(N)=O +COc1ccc(NC(=O)c2cc(-c3ccc(Cl)cc3)nn2C)cn1 +Cc1ccc(C(=O)Nc2ccc(N3CCCC3=O)cc2)cn1 +CCc1cnc(NC(=O)Nc2c(C)nn(C)c2OC)s1 +Cc1cccc(C(=O)N2CCCC(C(=O)Nc3ccccc3)C2)c1 +Cc1cc2c(=O)n(Cc3ccc(C#N)cc3)cnc2s1 +CC(C)C(NC(=O)c1ccco1)C(=O)Nc1ccc2[nH]ncc2c1 +COc1ccccc1OCCC(C#N)C(=O)N1CCCCCC1 +COCC1CCCN1C(=O)Nc1cnn(-c2ccccc2F)c1 +CCc1c(-c2ccco2)nn(-c2ccccn2)c1N +CCNc1cc(C(C)C)nc(-c2ncccc2C)n1 +CC(C)n1cc(C(=O)Nc2cnn(C)c2)c2ccccc2c1=O +COC(C)(CNC(=O)c1c(C)nc2ccccn12)c1ccccc1F +CCCCN(C)S(=O)(=O)Nc1cccc(C#N)c1 +Cc1ccc2nc(-c3ccco3)nc(N3CCOCC3)c2c1 +Cc1cc(C(=O)Nc2cn[nH]c2)c2ccccc2n1 +N#Cc1cccc(NC(=O)NCC2COCCO2)c1 +CC(C)(C)c1ccc(-c2ncc(C(N)=O)c(N)n2)cc1 +COc1cc(CNC(=O)c2cccnc2O)ccn1 +O=C(CC1CC1)N1CCc2ncnc(-c3cccnc3)c2CC1 +O=C(CN1CCc2ccccc21)NCCc1ccc2c(c1)OCCO2 +CN(Cc1nc(N(C)C)ncc1-c1ccncc1)C(=O)C(C)(C)C +CC1Oc2ccccc2OC1C(=O)Nc1cc(F)cc(F)c1 +COc1ccc(F)cc1NC(=O)N1CCC(N2CCNC2=O)CC1 +CCOC(=O)Nc1cccc(OC(C)C(=O)Nc2cc(C)on2)c1 +Cn1nc(C(=O)N(Cc2cccs2)CC2CCCO2)ccc1=O +Cc1ccc2c(C)c(C(=O)N3CCC(c4nncn4C)CC3)oc2c1 +CC1(C)OCC2(CO1)CN(C(=O)CSc1ccc(F)cc1)C2 +Cc1cc(NC(=O)c2csc(Nc3nc(C)cc(C)n3)n2)sn1 +Cc1nc2sccn2c1C(=O)N1CCc2c(nc(N)[nH]c2=O)C1 +CCS(=O)(=O)N1CCCC(CCc2ccc(F)cc2F)C1 +Cc1cc(Cl)ccc1N1CCN(C(=O)C2CC2)C(C)C1=O +COC(=O)c1ncc(C(C)(C)O)cc1Br +O=S(=O)(NCCc1ccccc1)c1cccc(O)c1 +COCCOc1ccc(NS(=O)(=O)c2ccccc2)cc1F +O=C(NCCn1ccc(-c2ccccn2)n1)Nc1ccccc1 +Cc1ccc2[nH]nc(C(=O)Nc3ccc4c(c3)NC(=O)CO4)c2c1 +CC(C)n1nccc1NC(=O)CCc1nnc(-c2ccccc2)o1 +O=C(OCc1ccc(F)cc1)c1cccc(OCC(F)F)n1 +COC(=O)c1cc(-c2cc(Br)ccc2F)n[nH]1 +Nc1ccc(F)cc1N1CCN(CC(F)(F)F)CC1 +CCOC(=O)Nc1cccc(C(=O)Nc2ccccc2O)c1 +CC(=O)NCCNC(=O)NC1CCCN(Cc2ccccc2)C1=O +Cc1nc(C)c(CCC(=O)NC2(C(N)=O)CCCCC2)c(=O)[nH]1 +OCCCNc1cc(-c2ccccc2)nc(-c2cccnc2)n1 +C=CCNc1cc(=O)n(C)c(=O)n1Cc1ccccc1 +COC(=O)c1cc(N)n(-c2ccc(C)c(Cl)c2)n1 +Clc1cnc(N2CCN(CC3=CC=CC4N=CC=C34)CC2)nc1 +Cn1cc(C(=O)NCc2ccc(-c3ccc(Cl)cc3)o2)cn1 +Fc1ccc(CN2CCNc3ccccc32)cc1F +CC(Sc1ccccc1Cl)C(=O)Nc1ccc(C(N)=O)cc1 +Cc1ccn2c(=NC(=O)Cc3ccc(C)nc3)[nH]nc2c1 +CCCC(=O)N1CCCC(c2nn(C)c(=O)n2-c2ccccc2)C1 +CC(C)Oc1ccc(CN2CCNc3ccccc32)cc1N +CCC(C)NC(=O)c1cc(OC)c(OC)cc1N +COc1ccc(C(=O)Nc2cc(C)nn2C(C)(C)C)cc1 +Cn1nc(C(=O)Nc2ccccc2OCCn2cccn2)ccc1=O +c1csc(-c2nn(Cc3ccncc3)c3c2CNCC3)c1 +Cc1ccc(C#N)cc1NC(=O)CNC(=O)NC1CC1 +O=C(CCNc1ncnc2[nH]cnc12)N1CCCCC1 +CC(=O)N1CCC2(CC1)CCN(C(=O)c1ccc(N(C)C)cc1)C2 +COc1cccc(C(=O)Nc2cccc(N)c2C)c1 +CC(=O)c1cccc(NC(=O)CS(=O)(=O)c2ccc(C)cc2)c1 +C#CCNC(=O)N1CCCN(c2ncccc2C#N)CC1 +CC(C)CN(CC(C)C)C(=O)c1ccc(N2CCNC2=O)cc1 +Cn1c(=O)c2c(-c3ccccc3)n(-c3ccccn3)cc2n(C)c1=O +O=C1C2CCCN2C(c2cccc(Cl)c2)N1c1nccs1 +CCOC(=O)c1c(S(=O)(=O)N2CCCCC2)n[nH]c1C +CC(C)NC(=O)CN(C)c1ccc2ccccc2c1 +CNc1cccc2c(OCC3CCCO3)nc(C)cc12 +CCN(Cc1ccoc1)C(=O)NCCNC(=O)c1cccc(C)c1 +CN1CCC(C#N)(NS(=O)(=O)c2cccs2)CC1 +CC(CC(N)=O)Oc1ccc(-c2ccccc2)cc1 +Cc1cnc(CSc2ncc(-c3ccccc3)o2)cn1 +COc1ccc(C(O)CCC(=O)N2CCCC2)cc1OC +CCC(C)NC(=O)c1ccc(Cl)cc1-n1cnnn1 +CC1CCN(c2ccc(C(=O)Nc3ccc4c(c3)COC4)cn2)CC1 +O=C(c1ccc(F)cc1)N1CCN2C(=O)C3CCCN3C(=O)C2C1 +O=C(NCC(F)(F)F)Nc1ccccc1Br +O=C(COC(=O)C1CC=CCC1)Nc1ccc2c(c1)OCCCO2 +CC(NS(C)(=O)=O)C(=O)N1CCOc2ccccc21 +CC(=O)C(NC(=O)COCC1CCOC1)C(C)C +CCN(CC)C(=O)C1CCN(C(=O)Nc2ccc3c(c2)COC3)CC1 +O=C(NCC1CCN(C(=O)c2cccnc2)CC1)c1ccccn1 +CCn1nc(C)c(CCNC(=O)CCc2c(C)nn(C)c2C)c1C +CCC(=O)N1CCCCC1C(=O)NC(C)c1cc(C)sc1C +CCCn1c(C)nnc1CNc1cccc(Cl)c1 +O=C(Cn1nnc(-c2ccccc2)n1)Nc1ccnn1C1CCCC1 +CC(=O)NCCNC(=O)Nc1ccc(-n2ncc3ccccc32)cc1 +CCOC(=O)C(C)(C)N(C)C(=O)c1ccc(Cn2cncn2)cc1 +O=S(=O)(Oc1ccc(-n2cccn2)cc1)c1ccccc1F +Cc1cccc(OC(C)C(=O)N2CCOCC2C2CC2)c1 +CCn1cc2c(n1)-c1c(oc(C(=O)N3CCOCC3)c1C)CC2 +CC(C)NC(=O)N1CCN(C(=O)c2n[nH]c3cc(Cl)ccc23)CC1 +CCS(=O)(=O)NCc1ccc(F)cc1C(F)(F)F +O=C(C1CC1)N1CCN(S(=O)(=O)c2cccc3nonc23)CC1 +CCC(=O)Nc1ccc(C(=O)Nc2ccc(Cl)cn2)cc1 +CS(=O)(=O)N1CCC2OCC(C(=O)NCc3ccco3)CC2C1 +COCCn1cnc2c([nH]c3cc(C)ccc32)c1=O +Cc1cccc(CC(=O)OCC(=O)Nc2ccccc2F)c1 +CCC(C)NC(=O)CCNC(=O)Nc1cnc2c(c1)c(C)nn2C +CN(CC1CC1)C(=O)Nc1cnn(-c2ccccc2F)c1 +C#Cc1cccc(NC(=O)N(CCOC)C(CC)CC)c1 +COC(=O)c1cccc(NC(=O)N2CCCC(C)C2)c1 +Cc1cc(C(=O)Nc2nc3ccccc3s2)ccc1N +O=C(NCCc1csc(N2CCCC2)n1)NCC(F)(F)F +O=C(COC(=O)c1ccc2c(c1)CCC2)NCc1cccs1 +CCCNC(=O)CSc1nc(C2CC2)nc(C)c1C(C)=O +O=c1[nH]c(Nc2ccccc2Cl)nc2nccc(-c3ccncc3)c12 +O=C(NCC(O)c1ccc(F)cc1)Nc1nccs1 +CC1(C)CN(CCOCCOc2ccccc2)CCO1 +O=C(CCn1c(=O)oc2ccccc21)NC1CCCCC1 +O=C(Cc1cccnc1)NCCS(=O)(=O)c1ccccc1F +CC1CCN(C(=O)c2csc(Cc3ccccc3)n2)CC1O +O=C(NCc1ccccn1)c1ccc(-n2cnc3cccnc32)cc1 +COC(=O)c1sccc1NC(=O)c1c(C)c(=O)on1C +CC(=O)Nc1ccc(Sc2ccc3nnnn3n2)cc1 +Cc1nc(COC(=O)c2cnn(CC(C)C)c2C2CC2)sc1C +C#Cc1cccc(NC(=O)CCCCNC(N)=O)c1 +Cc1csc(NC(=O)c2ccc(COc3ccccc3)o2)n1 +Cc1cc(O)c(C(C)C)cc1C(=O)c1ccncc1 +O=C(C1CCC(=O)N(C2CC2)C1)N1CCC(c2ccccc2)CC1 +CCC(NC(=O)C(C)OC)c1cccc(Cl)c1 +Cn1cc(-c2nc(C(=O)OCc3ccc(C#N)cc3)cs2)cn1 +CN(C)S(=O)(=O)Nc1ccn(CC(F)F)n1 +CC(C)(C)OC(=O)N1CCCC(Nc2nc3ccccc3nc2N)C1 +C=C(C)CN(CC)C(=O)CN1CCN(C(=O)NCC)CC1 +Cc1ccc(NC(=O)NCc2cccc(Cn3ccnc3)c2)c(F)c1 +O=C(CCn1cc(Cl)cn1)Nc1nncs1 +Cc1nc2ccc(NC(=O)N(C)Cc3c(C)noc3C)cc2o1 +CCN(CCOc1ccc(OC)cc1)C(=O)c1ncc(F)cc1F +Cc1ccc(CN(CC(=O)NC(C)(C)C)C(=O)c2csnn2)cc1 +CC(C)Cn1ccn(-c2cccc(F)c2)c(=O)c1=O +CCc1ocnc1C(=O)N(C)CCc1nc2c(C)cccc2[nH]1 +COC(=O)c1ccnc(N2CCCN(C(=O)C3CCCO3)CC2)c1 +Cc1csc(NC(=O)c2ccc(=O)n(C)n2)n1 +Nc1ccc2c(c1)N(CCOc1ccc(Cl)cc1)C(=O)CO2 +Nc1ccc(Cl)c(C(=O)NCc2ccccn2)c1 +Cc1ccc(C(=O)Nc2ccc(CC#N)cc2)cc1F +COc1ccccc1C(=O)Nc1ccc(N(C)C)cn1 +CCCn1nnnc1CSc1nnc(C2CC2)n1-c1ccccc1 +Cc1cc(C)c(C(=O)N2CCC(c3nc(C)cs3)CC2)c(C)c1 +CC(C)N(C)C(=O)c1ccc(OCc2ccccc2C#N)cc1 +Cc1ccc(C)c(-n2c(C)cn3c4c(=O)n(C)c(=O)n(C)c4nc23)c1 +CC(=O)N(C)c1ccc(NC(=O)Cc2ccsc2)cc1 +NC(=O)c1c(O)c2ccccc2n2c(=O)c3ccccc3nc12 +COc1ccc(CNC(=O)C2(c3cccc(Cl)c3)CC2)cc1O +CC(C)NC(=O)CN(C)C(=O)C1(c2ccc(F)cc2)CC1 +CCN(C)S(=O)(=O)N1CCOc2ccccc2C1 +C#CCN1C(=O)c2ccccc2NC1c1ccccc1F +COC1CCC(OC(=O)c2ccc(-n3ccnc3)cc2)CC1 +CC(=O)Nc1cccc(-c2nn(CCC#N)c3c2CNCC3)c1 +CC(NC(=O)NCCc1ccc2c(c1)OCO2)c1nncn1C +CC(C)Oc1ccc(NC(=O)CCn2cccn2)cc1 +O=C(c1cc(-c2cccc(F)c2)no1)N1CCCC1c1ccncc1 +Cc1nn(-c2ccccc2)c(O)c1C1=Nc2ccccc2C1=O +CC(C)OCC(O)CN1CCN(C(=O)c2ccco2)CC1 +Clc1cccc(-c2c[nH]c(C3COCCN3)n2)c1 +CCc1ccc(C(=O)Nc2ccc(-c3nncn3C)cn2)o1 +Cc1nc(C2CCCN(C(=O)c3ccc(Cl)c(C)c3)C2)cc(=O)[nH]1 +O=C(Nc1nc(C(F)(F)F)cs1)c1ccc2c(c1)OCO2 +COc1ccccc1NC(=O)C(C)NC(=O)c1cccs1 +O=C(Cc1cccc(F)c1)Nc1cccc(Cn2cccn2)c1 +Cc1ccc(C(=O)NCc2ccc(Cn3ccnc3)cc2)c(=O)[nH]1 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)N1CCc2sccc2C1 +COc1ccc(C(C)Nc2nc(C(F)(F)F)cc(=O)[nH]2)cc1 +O=C(Nc1ccn(Cc2ccccc2)n1)NC1CCC(O)CC1 +CCC(=O)N(C)CC(=O)Nc1ccc(Br)cn1 +CC(=O)NCC(=O)Nc1cc(NC(=O)Nc2ccccc2)ccc1C +CCCNC(=O)C(C)NC(=O)N1CCn2c1nc1ccccc12 +Fc1ccccc1-c1cc(NC2CC2)nc(-c2cccnc2)n1 +CCN(CC)c1ncc(CNc2cccc(O)c2)s1 +COc1ccc2c(c1)CC(NC(=O)NCCc1cccs1)CO2 +O=C(OCC1c2ccccc2-c2ccccc21)N1CCC(O)C1 +O=C(CCc1ccccc1)N1CCN(C(=O)C2CCCC2)CC1 +O=C(Nc1nccs1)N1CCCC1c1ccc[nH]1 +CCCn1ncc2cc(C(=O)NC(C)CC)c(N)nc21 +COc1ccc(C(NC(=O)Cn2ccnc2)C(C)C)cc1 +Fc1cccc2c1CCNC2c1ccc2nc[nH]c2c1 +CC(C)n1cc(NC(=O)c2nnc3ccccc3n2)cn1 +O=C(Nc1nc(-c2cccnc2)cs1)c1ccc(F)cc1F +Cc1cc(Nc2ncnc3c2CCN(C(=O)Cc2ccccc2)C3)[nH]n1 +COc1ccccc1-n1nnnc1SC(C)C(=O)NC1CCCC1 +CCN(C(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1)C1CC1 +CC(C)c1ncc(Cl)c(C(=O)NCc2ccccc2Cl)n1 +Cc1ccccc1C(=O)NCC(=O)NCC(C)Oc1ccccc1 +CCCOc1ccc(CNC(=O)c2ccc(C)cc2)cc1OC +NC(=O)CCNS(=O)(=O)c1cc(N)c(F)cc1F +O=C(NCc1nncn1C1CC1)Nc1ccc(N2CCCCC2)cn1 +Cc1ccc(NC(=O)C2CCCN2C(=O)c2cccs2)c(C)c1 +CCCN(C)c1cc(Oc2ccc(F)cc2F)ncn1 +CCn1c(-c2cc(NC(=O)COC)[nH]n2)cc2ccccc21 +CC(C)(CNC(=O)CNC(=O)c1cccc(F)c1)N1CCOCC1 +CC12CN3CC(C)(CN(C1)C3c1cnc3ccccc3c1)C2=O +COc1ccccc1NC(=O)COC(=O)c1ccc2c(c1)CCC2 +O=S(=O)(Nc1cccc(Cl)c1)c1cccc(O)c1 +COCCCNC(=O)C1CC(=O)N(c2ccc(C)c(Cl)c2)C1 +Cc1cc(C)n(CC(C)CNC(=O)c2ccc[nH]c2=O)n1 +Cc1nnc(SC(C)C(=O)Nc2ccccc2F)n1N +O=C(CCn1c(=O)oc2ccccc21)NCCc1cccnc1 +O=C(CN1CCN(c2ccc(F)cc2)CC1)NCc1ccco1 +O=C(NCc1ccc2c(c1)OCO2)c1ccc(N2CCOC2=O)cc1 +COc1cc2nc(-c3ccccc3Cl)oc(=O)c2cc1OC +Cc1cc(C)c(C(=O)N2CCCC(c3nncn3C3CC3)C2)c(C)c1 +O=C(NCc1ncc[nH]1)Nc1ccc2[nH]ccc2c1 +CCC1CCCCC1NC(=O)NCCCN1CCOCC1 +COCc1ccccc1C(=O)Nc1ccc2c(c1)COC2 +COc1cc2nc(SCC#N)n(N)c(=O)c2cc1OC +CCn1cc(S(=O)(=O)N2CCN(C(C)COC)CC2)cn1 +Cc1ccc(F)c(S(=O)(=O)N=c2cc(C)cc[nH]2)c1 +Cc1ccnn1CC(C)CNC(=O)Nc1cccc(Cl)c1 +N#Cc1cccc(COc2ccc(-n3cnnn3)cc2)c1 +CN(Cc1ccncc1)c1c(F)cc(C#N)cc1F +CN(Cc1ccccn1)C(=O)c1c[nH]nc1-c1ccc(Cl)cc1 +Cc1c(Cl)cccc1NC(=O)c1cnc(C2CC2)nc1N +CCc1nnc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)s1 +COc1cccc(C(=O)NCCNc2cccc(F)c2C#N)c1 +CC(C)(C)c1nc(CNC(=O)c2ccnc(OC3CCC3)c2)cs1 +Cc1nc(N2CCOCC2)nc2c1CCN(C(=O)C1CCC1)CC2 +N#Cc1cccc(NC(=O)CCC(=O)N2CC(=O)Nc3ccccc32)c1 +CC(C)Cc1cc(C(=O)NCCCC(N)=O)[nH]n1 +CC(C)c1cccc(CSc2nnnn2C2CCOCC2)n1 +Cc1cccc(C)c1-n1nnnc1SCC(=O)Nc1nccs1 +Cc1onc(-c2ccc(F)cc2F)c1C(=O)N1CCCCCC1 +CN(CCN(C)C(=O)c1ccco1)C(=O)c1ccco1 +CCc1ncc2c(n1)CN(C(=O)c1ccc3c(c1)OCC(=O)N3)C2 +CC(=O)Nc1ccc(NC(=O)c2ccc(N)cc2)cc1 +CN(C)C(C(=O)NCCCN1CCCC1=O)c1cccc(F)c1 +COc1ccc2c(ccn2CC(=O)N2CCCC2c2cnn(C)c2)c1 +Cc1cccc(OCCC(C#N)C(=O)N2CCCC2)c1C +O=C1OC(C(=O)Nc2ccc3oc(=O)[nH]c3c2)Cc2ccccc21 +N#Cc1cc2c(n(-c3ccccc3Cl)c1=O)CCNC2 +CS(=O)(=O)N(CC(=O)N1CCCC1)Cc1ccccc1 +NC(=O)C1Cc2ccccc2CN1C(=O)CCNC(=O)c1ccco1 +COc1ccccc1C(=O)c1nc2ccccc2n1C +COc1ccc(C(=O)Nc2ccc(C#N)cc2)c(OC)c1OC +COc1ccc(NC(=O)CNc2cccc(C#N)c2)c(OC)c1 +O=C(CC1CCCN1Cc1cncs1)c1ccccc1 +COc1cccc(Cn2c(=O)c3ccccc3n3nc(C)cc23)c1 +COC(=O)N1CCN(C(=O)C2CC(=O)N(Cc3cccnc3)C2)CC1 +O=C(Nc1nccs1)N1CCN(Cc2cscn2)CC1 +CCn1cnnc1C1CCN(C(=O)c2csc(C(C)C)n2)CC1 +CN(CC(N)=O)C(=O)c1ccc(Br)cc1O +O=C(Nc1ccccc1-n1ccnc1)c1cnn(-c2ccccc2)c1 +Cn1cc(C(=O)N2CCN(C(=O)c3cnn4ccccc34)CC2)nn1 +CCOCCS(=O)(=O)N1CC=C(c2ccccc2Cl)CC1 +CC(C)OC(=O)c1ccc(N2CCN(c3ccc(F)cc3)CC2)nc1 +CN(CCc1noc(C2CC2)n1)C(=O)C1CC(=O)N(C(C)(C)C)C1 +Cc1ccc(C(=O)CN2CCNc3ccccc32)cc1 +CCCCSc1n[nH]c(=O)n1CCc1ccccc1 +CCN(CC)C(=O)C1CC=CCC1C(=O)Nc1ccccc1 +CCOc1ccc(SCC(=O)N2CCOCC2C2CC2)cc1 +O=C(CCC1CCCO1)N1CCN(CC(O)c2ccccc2)CC1 +CNC(=O)CSc1ncccc1-c1noc(C)n1 +COc1cccc2c1OCC(C(=O)NCCCc1c(C)n[nH]c1C)C2 +O=C(Cn1ccc(C(F)(F)F)n1)Nc1ccc(F)c(Cl)c1 +CCOc1cc(CNc2ccccn2)cc(Cl)c1O +O=C(COc1ccccc1F)NCc1cc(-c2cccs2)on1 +CC1=CCC2CN(C(=O)CCc3cccnc3)CC2C1 +CCOc1cc(F)ccc1NC(=O)CCSc1nnnn1C +CC(C)C(=O)NCCNC(=O)c1cncn1-c1ccccc1 +CC(C)c1nnc(SCCCc2cn[nH]c2)n1C1CC1 +C=CCNC(=O)c1nnc(N2CCCCC2)c2ccccc12 +Cc1occc1CN(C)C(=O)Nc1ccncc1F +COc1ccc(C#CCNC(=O)c2ccc(N(C)C)cc2)cc1 +COc1ccccc1C(C)NC(=O)C(C)n1cnc2ccccc21 +Cn1cc(C(=O)Nc2ccncc2)c(=O)c2cccc(Cl)c21 +O=C(Cc1cccnc1)N1CCc2[nH]nc(-c3ccccc3)c2C1 +Cc1cc(NC(=O)c2ccc3c(c2)NC(=O)CS3)no1 +CCCOC1CCCN(C(=O)c2cc(Cl)c[nH]2)C1 +CCOc1ccc(-c2nnc(SCCC(=O)N3CCCC3)o2)cc1 +CSc1cc(C(=O)N(Cc2cccc(F)c2)C2CC2)ccn1 +Cc1cc(NC(=O)CSc2nccn2C)ccc1Br +CCOc1ncccc1NC(=O)c1ccc(C)cc1C +CCCCn1nc(C(=O)NCC2COc3ccccc3O2)ccc1=O +O=C(CN1CCc2nc(NC(=O)C3CCC3)sc2C1)NC1CC1 +CC(C)CCCOC(=O)c1cn(C)nc1C(F)(F)F +c1ccc(-c2nnn(Cc3coc(-c4ccccc4)n3)n2)cc1 +COC(=O)C(C)CN(C)C(=O)NC1CCCCC1 +CCOC(=O)c1coc(C(=O)NC2CCCC2)n1 +Cc1c(C(=O)N2CCNC(=O)C2)sc2ccc(F)cc12 +CN(C)S(=O)(=O)c1ccc2[nH]c(-c3cnn(C)c3)nc2c1 +CCOc1ccc2nc(NC(=O)CCOC)sc2c1 +CC1CCCC(CNC(=O)CCc2nc(-c3ccncc3)no2)C1 +O=C(CNC(=O)c1sc2ccccc2c1Cl)Nc1cccnc1 +CC(C)(C)OC(=O)Cc1cccc(NC(=O)Cc2ccc[nH]2)c1 +Cn1nnnc1SCC(=O)N1CCC2CCCCC2C1 +CN(Cc1nnc2ccccn12)C(=O)c1cccc(OCC(F)F)n1 +CC(NC(=O)CC1CCCCC1)C(=O)Nc1cccc2[nH]cnc12 +CC(C)N(C(=O)c1cc(NC(=O)C2CC2)c(=O)n(C)c1)C(C)C +CN(Cc1cccnc1)C(=O)C1CC2CCCC(C1)C2=O +CC(C)(C)C(=O)NCCc1nc(-c2ccccn2)no1 +CC(c1ccc2c(c1)OCCCO2)N(C(=O)c1cnccn1)C1CC1 +Cn1ccnc1SCC(=O)N1CCn2c1nc1ccccc12 +COCCC(=O)NC(C)c1cnc(N(C)C2CCCCC2)nc1C +CC(C)c1nc(CN(C)C(=O)Nc2ccnn2C(C)C2CC2)cs1 +COC(=O)C(NC(=O)c1cc(SC)ccc1C)C(C)C +CCOc1ccc(NC(=O)Cn2c(N)nc(CC)cc2=O)cc1 +COC(=O)c1ccc2c(=O)nc3n(c2c1)Cc1ccccc1-3 +CC(C)Cc1nc(CN2CC(Cc3ccccc3)CC2=O)no1 +CCC(C)NS(=O)(=O)c1cc(C(=O)C2CC2)ccc1F +Fc1cc(Cl)ccc1-c1nnc2sc(-c3csnn3)nn12 +Cc1ccsc1C(=O)NCc1ccnc(-n2cccn2)c1 +CCCC(C)C(=O)N1CCC(C(=O)NCc2ccccc2)CC1 +Cc1cc(C)cc(C(=O)NCc2ccc(-c3csc(C)n3)o2)c1 +O=C1COc2cc(NC(=O)C3CC3c3ccccc3)c(Cl)cc2N1 +Cc1ccc(C(=O)Nc2nnc(Cc3ccccc3)s2)o1 +CCCCN(C)C(=O)c1cc2ccccc2c(=O)[nH]1 +CCCCC(=O)NCC(=O)c1ccc(OC)c(C)c1 +COc1cccc(-c2cnc(N)nc2)c1C(=O)N(C(C)C)C(C)C +Cn1ccc(C(=O)NCc2ccnc(OC3CCC3)c2)cc1=O +CN(C)C(=O)N1Cc2nnn(C)c2C(COCc2ccccn2)C1 +COCC(C)NC(=O)c1cc(-c2ccc(Br)cc2)on1 +CCCn1c(C)nnc1SC1CCN(c2cc(C)nn2C)C1=O +O=C(Nc1nnc(-c2ccno2)o1)c1ccc(F)cc1 +COC(=O)c1c(C)nc(C)c(C(=O)OC)c1-c1cccnc1 +CCN(C(=O)CCC(=O)Nc1nccs1)C(C)c1ccc(F)cc1 +Cc1ccc(C(N)=O)cc1NC(=O)c1cnc(C2CCCO2)s1 +Cc1cc(C(=O)N2CCCCC2)ccc1N1CCCS1(=O)=O +CC1CNc2cc(S(=O)(=O)N3CCOCC3)ccc2O1 +Cc1nc(C)n(CCCNC(=O)Cc2c[nH]c3ccccc23)n1 +CC(C)CN(CC(C)C)C(=O)CSc1ccccn1 +CCOc1ncc(C(=O)N(CC)c2ccc(OC)nc2)cc1Cl +C=C(C)CN1C(=O)CSc2nnc(COc3ccccc3)n21 +CNC(=O)c1nc(N(C)C)c2c(C)scc2n1 +COC(=O)CCC(=O)Nc1ccc(C#N)c(Cl)c1 +O=C(NCc1cccs1)N1CC(c2nc(-c3cccs3)no2)C1 +O=C(c1ccc[nH]c1=O)N(CC(F)(F)F)C1CCOCC1 +Cc1cc(C)n2nc(SCc3n[nH]c(=O)[nH]3)nc2n1 +O=C(NCc1ccccc1CO)Nc1ccc(F)c(F)c1F +CN(C(=O)CN(CCC#N)Cc1ccco1)c1ccccc1 +CN(Cc1cccc(C#N)c1F)C(=O)OC(C)(C)C +CN(Cc1ccccc1Br)C(=O)NCc1cscn1 +CC(C)OC1CCC(NC(=O)N2CCOCC2C2CC2)CC1 +Cc1noc(COC(=O)Cc2csc(-c3ccoc3)n2)n1 +COc1ccc(NC(=O)CCC(=O)c2cccs2)cc1 +COC(=O)CCN1C(=O)CCc2cc(F)ccc21 +CCN1CCN(S(=O)(=O)Cc2ccc(Cl)c(Cl)c2)CC1 +CSc1ncc(C(=O)NCCNC(C)=O)n1-c1ccccc1 +CCC(C)c1ccc(C(O)CNS(=O)(=O)N(C)C)cc1 +COc1cccc(CNC(=O)C(C)Sc2n[nH]c(N)n2)c1 +CCCn1ccnc1SCC(=O)Nc1ccccc1C(F)(F)F +NC(=O)C1(CNC(=O)Cn2ccc3ccc(Cl)cc32)CCOCC1 +Cc1c(NC(=O)NCc2cccs2)cccc1C(N)=O +COCCNC(=O)c1ccc(OCC(N)=O)c(N)c1 +Cc1[nH]c(=O)c(C(=O)N(C)c2ccccc2)c(C)c1N +Cc1noc(-c2ccc(=O)n(CC(=O)Nc3ccccc3F)c2)n1 +Cc1cc(C(=O)NCC(C)N2CCc3ccccc32)on1 +Nc1ccc2c(c1)nc(-c1ccncc1)n2C1CCCC1 +COc1cccc(C2CCN2C(=O)Cc2cnc3c(C)cccn23)c1 +Cc1cc(NC(=O)COC(=O)C2CC(=O)N(c3ccccc3)C2)no1 +CC1(C(=O)N2CCOCC2)CN(Cc2cccnc2)CCO1 +O=C(Nn1c(C2CC2)nc2ccccc2c1=O)c1cccc(Cl)c1 +Cc1csc(CNc2cnn(-c3ccccc3)c2C)n1 +CCn1cc(S(=O)(=O)N2CCCC(O)(CO)CC2)cn1 +CN(CC(=O)NC1CC1)C(=O)CNc1ccccc1F +CCCc1nnc(C(=O)N2CCN(c3cc(C)cc(C)c3)C(=O)C2)o1 +CC(=O)c1c(C)[nH]c(C(=O)N2CCCc3ccccc32)c1C +CCCn1nc(C(=O)Nc2ccc(Cl)c(Cl)c2)ccc1=O +CCCC1CN(C(=O)Cc2ccc(-n3cnnn3)cc2)CCO1 +O=C(NC1CCCC1)c1ccc(N2CCCC2=O)cc1 +CCOCCC(=O)NCc1cc2n(n1)CCCN(C(=O)C1CCC1)C2 +COc1ccc(NCC(=O)N2CCCCCC2)cn1 +CN(CCOCC1CC1)C(=O)Cn1c(=O)n(C)c2ccccc21 +CCC(Cn1ncc2ccccc2c1=O)NC(=O)C1CC1 +CCC(NC(=O)c1cc(N)ccc1Cl)C(C)C +O=C1CCCN1Cc1nnc(SCc2ccccc2F)o1 +O=C(NCC1CCCCO1)c1ccc(Cl)cc1O +O=C(Cn1cccn1)NCC(c1ccc(Cl)cc1)N1CCOCC1 +CC(C(=O)N1CCCCCC1)N1CCN(C(=O)CCC2CC2)CC1 +Cc1oncc1C(=O)N1CCC(C(=O)NCc2ccccc2F)CC1 +Cc1cnc2c(S(=O)(=O)NC3CCCCC3)cccc2c1 +CC1NCCN(c2ccc(Cl)cc2C(F)(F)F)C1=O +Cn1ccnc1C(OC(=O)c1cccc2cn[nH]c12)C(F)(F)F +COC(CNC(=O)Cn1c(=O)n(C)c2ccccc21)c1ccccc1 +O=C(NCC(=O)N1CCCC1)Nc1ccccc1-n1cccn1 +Cc1nc(NCCc2noc(-c3ccccc3)n2)c2nc(C)oc2n1 +O=C(c1ccc(C(=O)N2CCCCC2)cc1)N1CCCCC1 +CC(=O)NCCNS(=O)(=O)c1ccc(Br)cc1 +Cc1ccc(NC(=O)c2scnc2C)cc1S(C)(=O)=O +CN(C)C(=O)CNC(=O)Nc1cnn(CC(N)=O)c1 +Cc1c(C(=O)OCCOCC(F)(F)F)cnn1C +CN(C)S(=O)(=O)N1CCOC(c2ccncn2)C1 +CCc1nnc(NC(=O)CSc2nc(C(C)(C)C)cs2)s1 +Cc1csc(CNC(=O)c2cc(F)ccc2Br)n1 +COc1ccc2cc(C(=O)NC(C)CN3CCOCC3)[nH]c2c1 +N#CC(NC(=O)Cc1c[nH]c2ccc(Cl)cc12)C1CCOC1 +Cc1cc(NC(=O)C2CCC(F)(F)CC2)sn1 +CCn1c(CNc2cccc(CN(C)C(C)=O)c2)nc2ccccc21 +CC(C)C(CNC(=O)c1ccccc1)N1CCOCC1 +CCC(C(=O)Nc1nc(C(N)=O)cs1)c1ccccc1 +O=S(=O)(NCC1(c2ccccc2)CCOCC1)c1cccs1 +CC(C)C(C)NC(=O)CNc1cc(C(=O)N(C)C)ccc1Cl +CCc1ccc(NC(=O)c2nnn(Cc3ccccc3)c2N)cc1 +COCC#CCSc1nc(-c2ccccc2F)n[nH]1 +CCN(C(=O)CS(=O)(=O)c1ccccc1C)C1CCCCC1 +O=C(C1CCCN1C(=O)c1cccs1)N1CCC2(CCOC2)C1 +O=S(=O)(Cc1cccc(C(F)(F)F)c1)N1Cc2cncnc2C1 +Cc1cc(C(=O)N(C)C2CCCCC2C)c(C)n1Cc1ccccn1 +CCCc1nnc(C(=O)N2CCc3c(nc(CC4CC4)[nH]c3=O)C2)o1 +Cc1ccc(SCCNC(=O)COc2ccccc2C#N)cc1 +COc1ccc(NC(=O)C2CC2)cc1N1CCCCC1=O +N#Cc1ccc(C(=O)N2CCCN(c3nc4ncccc4o3)CC2)cc1 +CC(C)Oc1ccc(-c2nc3cc4c(cc3[nH]2)OCCO4)cc1N +CC(=O)N1CCc2cc(C(=O)Nc3nc4c(s3)CCC4)ccc21 +O=C(Nc1onc2c1CCCC2)c1cc2ccccc2o1 +Cc1cc(C)cc(C(=O)OCCn2nc3ccccn3c2=O)c1 +Cc1cc(C)cc(NC(=O)c2c[nH]c3ccc(Cl)cc3c2=O)c1 +Cc1nc2ccccc2nc1CN1CCc2cnc(C(C)C)nc2C1 +CCOC(=O)Nc1cccc(NCc2noc(C3CC3)n2)c1C +Cc1cnc(C(C)(C)NC(=O)NCc2ncn(C)n2)s1 +O=C(Cc1ccccc1F)NC1CCN(c2c(F)cccc2F)C1 +CC(C)n1nnc2cc(C(=O)NC3CCCC3)ccc21 +O=C(c1ccco1)N1CCCC(c2nc(-c3cccs3)no2)C1 +CCN1CCN(C(=O)CCC(=O)c2cc(C)ccc2C)CC1 +O=C(NCCn1cccc1)C1(c2ccc(F)cc2F)CCCC1 +C=C(C)COc1cccc(C(=O)N2CCCCC2CCO)c1 +COc1ccc(N(C)C(=O)c2ccc(-n3cnnc3)cc2)cc1Cl +C=CCN(Cc1cc(Br)ccc1F)Cc1c[nH]nc1C +O=C(NCC1CCCCO1)c1cc(F)ccc1F +Cc1ccc(CCNC(=O)NC2CCN(CC(F)(F)F)C2)c(C)c1 +CCn1ccc(C(=O)N2CCN(CCc3ccccc3)CC2)n1 +Cc1nccc(C(=O)NCCCn2ccc3ccccc32)n1 +O=C(Nc1cccc(OC(F)F)c1)Nc1nccs1 +COc1ccc(-c2noc(CC(=O)Nc3cc(C)on3)n2)cc1 +COC(=O)c1nnc2nc(C(F)(F)F)nn2c1C +COCC(=O)N1CCN(C(=O)c2ccccc2N2CCOCC2)CC1 +Cc1ccc(-n2nnc(C(=O)NC3CCCC3)c2C)cc1 +C=CCCCN(C)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +COc1ccc(OCC(=O)Nc2cc(F)ccc2F)cc1 +Oc1ccc(F)cc1-c1ccnn1-c1ccccc1 +Cc1c(C(N)=O)sc2ncn(CCc3ccccc3)c(=O)c12 +CCCNC(=O)CCNC(=O)Nc1ccc(Cl)c(F)c1 +CC1CCC(C)N(C(=O)Nc2ccc(Oc3ncccn3)cc2)C1 +CCN1C(=O)CCCC12CCCN(C(=O)c1c(C)noc1C)C2 +O=C(c1ccccc1)c1cnc2ccc(Br)cn2c1=O +CC(C(=O)Nc1ccncc1)(c1ccccc1)c1ccccc1 +O=C(NCC1COC2(CCCCC2)O1)c1ccco1 +Cc1ccc(N2CC(C(=O)N(C)Cc3ccc(C)o3)CC2=O)cc1 +COc1cccc(NC(=O)N2CCN(C)c3ncccc32)c1 +CCN(Cc1nc(COC)no1)C(=O)c1cccc(NC(C)=O)c1 +CCNc1nc(-c2cccn(CC(C)C)c2=O)cs1 +O=C(CCc1c[nH]c2ccccc12)Nc1ccccc1-n1cncn1 +CCCc1nc(CS(=O)(=O)c2ccc3ccccc3n2)cs1 +O=C(NCCN1CCOCC1)NCc1nc2ccccc2s1 +Cc1cc(C(=O)COCC2CCCCO2)c(C)n1C +O=C(Cc1ccc(O)cc1)Nc1ccc(OC(F)(F)F)cc1 +Cc1cc(C(C)NC(=O)Nc2cccc(Cl)c2)c(C)o1 +Cc1cc(CNC(=O)c2cccnc2Nc2cccc(F)c2)on1 +Cc1occc1-c1nnc(Sc2ccc(C#N)cn2)n1C +Cc1ccc(C(=O)NCCNC(=O)c2ccc(O)cc2)c(O)c1 +Cc1ccc(CN2CCOC3C(OCc4ccncc4)CCC32)o1 +COc1ccc(CNC(=O)Nc2cnn(Cc3ccccc3)c2)cc1 +Cc1cc(C)n(CCCNc2cc(-c3ccccc3)nc3ncnn23)n1 +O=C(NCc1cccnc1)c1noc2ncnc(N3CCCC3)c12 +CC(C)Sc1ccccc1C(=O)NCc1ccccn1 +CCCCN1CCN(C(=O)c2ccc(C#CC(C)(C)O)cc2)CC1=O +COC1CC(NC(C)=O)C2OC(c3ccccc3)OCC2O1 +C=CCNC(=O)c1cccc(N2CCCCS2(=O)=O)c1 +O=C(C1CCC1)N1CCC2(CC1)Nc1cccnc1-n1cccc12 +COc1ccc2c(c1)CCCN2C(=O)CN(C)S(C)(=O)=O +Cc1cc(=O)n2ncc(-c3ccc(Cl)c(Cl)c3)c2[nH]1 +Cc1cc(C)n(CCCNC(=O)c2ccnc(-n3cncn3)c2)n1 +COc1cc(OC)cc(C(=O)Nc2ccc3ncn(C)c3c2)c1 +CCC1CCCN(C(=O)Nc2cccc(CN(CC)C(C)=O)c2)C1 +Cc1cccc2nc(Cn3ncsc3=O)cc(=O)n12 +Fc1ccc(-n2cnnn2)cc1NCc1ccccc1OC(F)F +O=C(NCc1ccc(OC2CCCC2)nc1)c1cn2cccnc2n1 +CC1CCc2sc3c(c2C1)-c1ncnn1-c1nncn1-3 +CC(O)CNS(=O)(=O)c1cncc(Br)c1 +CCc1ccc(S(=O)(=O)N2CCC(OC)CC2)s1 +Cc1cc(C)n(CCNc2nc(C)nc3oc(C)nc23)c(=O)n1 +COC(=O)COc1cccc(NC(=O)c2cc(C)on2)c1 +N#Cc1cc(C#N)c(SCc2ccc(F)c(F)c2)nc1N +CCCOc1ccc(NC(=O)Nc2ccccc2)c(N)c1 +Cn1nc(-c2ccncc2)cc1NC(=O)Cc1cccc(O)c1 +COc1cccc(OC)c1C(=O)N(C)C(C#N)c1ccccc1 +COc1ccc(C(=O)COC(=O)c2cc3c(s2)CCC3)cc1OC +COc1ccccc1OCc1nc(C(C)C)c(C#N)s1 +CCCn1nc(C)cc1NS(=O)(=O)c1ccc(F)cc1 +O=S(=O)(CCc1noc(-c2cccnc2)n1)c1ccccc1 +Cc1cccc(-n2ncc(C(=O)N(C)CC(N)=O)c2C)c1 +O=C(NCCc1ccsc1)Nc1ccccc1F +COC(=O)C(NC(=O)CCn1ncc(=O)c2ccccc21)C(C)C +CC(=O)c1c(C)nc2nc(SCC#N)nn2c1C +CCC(CNC(=O)NCc1cnn(C)c1)c1ccccc1 +C=CCNC(=O)N1CCC(C(=O)N2CCC(C)CC2)CC1 +CN(Cc1cnn(Cc2ccccc2)c1)C(=O)c1ccccn1 +CC(C)OCCCNC(=O)c1cnc2sc3c(n2c1=O)CCCC3 +Cc1occc1C(=O)Nc1cc(Cl)c(N)c(Cl)c1 +CCOCCCNC(=O)N1CCN(c2ncccn2)CC1 +CCn1c(=O)n(-c2ccccc2C)c(=O)c2sccc21 +Cc1ccc(N2CCOC3CN(C(=O)N4CCCC4)CCC3C2)nn1 +CC(=O)NCCNC(=O)C(C)NC(=O)c1ccoc1 +O=C(CC1C(=O)Nc2ccccc21)c1ccccc1 +O=C(NCCc1cccs1)c1cn(Cc2ccccc2)nn1 +O=C(NC1CCN(C(=O)c2n[nH]c3ccccc23)CC1)c1ccccc1 +COc1ccc(NC(=O)NCC(O)c2cccn2C)c(OC)c1 +Cc1cc(CN(C)c2ccc(Br)cc2N)no1 +CCN(C(=O)Nc1nc(C)c(C)s1)C(C)C(C)C +CN(CCC#N)C(=O)Nc1cc(-n2cccc2)ccc1F +COc1ncnc(N)c1CNCC(C)c1ccc(F)c(F)c1 +Cc1cnn(CC2CCCCN2C(=O)CCCc2ccccn2)c1 +CC(C)NC(=O)c1ccc(NC(=O)c2cccc(OC(C)C)c2)cc1 +Fc1ccc(NCc2nnc(-c3ccccc3)o2)cc1Cl +CC(C)(C)n1cc(C#N)c(NC(=O)c2ccnc(OCC(F)F)c2)n1 +CCN(CC1COc2ccccc2O1)C(=O)Nc1ccccc1F +Cc1ccc(CN2CCN3C(=O)N(C4CCOCC4)CC3C2)cc1 +COCCn1cc(CCNC(=O)Nc2ccccc2)c2cccnc21 +NC(=O)Nc1cccc(NC(=O)CC2CCCCC2)c1 +CCN1CCc2nc3c(OC)cccc3c(C#N)c2C1 +CC(=O)Nc1ccccc1SCC1CC1(Cl)Cl +COc1ccc(-c2cnccn2)c(-n2cccn2)c1 +Cc1ccc(NC(=O)C2CCCN2S(C)(=O)=O)c(C)c1 +CCN(CC(C)C#N)C(=O)COc1ccccc1C(N)=O +O=C(CCCc1nnc2ccccn12)Nc1ccc(F)cc1 +COc1cc2nc(CC(C)(C)C)oc(=O)c2cc1OC +Cc1ccc(C(=O)N2CCN(C(C)C(=O)NCC(C)C)CC2)cc1 +c1ccc2sc(CNc3ncnc4sccc34)nc2c1 +Cc1nc2ccccc2nc1CN(C)Cc1cnn(-c2ccccc2)c1 +COc1ccc(OC(=O)C(C)OCc2ccccc2)cc1 +O=C(CC1C=CCC1)NCC(=O)Nc1ccc(-n2cncn2)cc1 +CCOc1ccc2c(c1)S(=O)(=O)N=C(NCC1CCCO1)N2 +O=S(=O)(Cc1ccccc1)NCCc1ccc(F)cc1F +CCCc1nnc(NC(=O)CCNC(=O)c2ccccc2)s1 +CCCc1nnc(NC(=O)CNc2ccc(C)cc2C)s1 +O=c1nc2n(c3ccccc13)Cc1cn3ccccc3c1-2 +CC(NC(=O)c1cccc(Br)c1)C(=O)Nc1ccccc1 +CC(C)(C)CC(=O)NCC(=O)OCC1CCCC1 +COCCCOCC(=O)Nc1cccc(N)c1C +Cc1cc(NC(=O)COc2cc(C(=O)N(C)C)ccc2C)no1 +COc1ccccc1CC(C)N(C)Cc1cncs1 +COc1ccc(OC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)cc1 +Cc1cnn(CCC(=O)Nc2ccnn2C2CCCCC2)c1 +CCS(=O)(=O)c1ccc(N2CCCc3ccccc32)cc1N +CNC(=O)C(NC(=O)Nc1cccc(C#N)c1)c1ccc(F)c(F)c1 +O=C(NCc1ccccn1)c1ccn(COc2ccccc2)n1 +CCN(CC)c1c(OC)c(OC)cc2cnccc12 +COc1ccc(CNC(=O)CNC(=O)Nc2cccc(C)c2C)cc1 +CNC(=O)c1cnn(-c2ccccc2)c1NC(=O)c1ccc(C)cc1 +CC(=O)c1ccccc1NC(=O)c1ccc(Oc2cccnc2)cc1 +Cc1noc(C(C)C)c1C(=O)N1CCN(CC(C)O)CC1 +CCc1c(C)nc2n(c1=O)CC(C(=O)Nc1cccc(C)n1)CS2 +CS(=O)(=O)c1ccc(C(=O)OCc2ccc(Cl)cc2)cc1 +CS(=O)(=O)c1ccc(C(=O)Nc2cccc(O)c2)cc1 +O=C(NCC1Cc2ccccc21)c1ccnc(OC2CCOC2)c1 +O=C(Cn1cccn1)NCCc1ccc(OC2CCCC2)cc1 +CCc1noc(CC)c1CNC(=O)CN(C)S(C)(=O)=O +CCc1noc(CC)c1CNC(=O)c1cccc(C)n1 +N#Cc1ccc(-c2csc(C(C#N)C(=O)CCc3ccco3)n2)cc1 +CCOC(=O)c1cccc2nc(C#N)n(CC#N)c12 +Cc1ccc(C(=O)NCCN2CCCS2(=O)=O)c(O)c1 +Cc1cc(OCCSc2nnc(C)n2N)ccc1C(C)C +O=C1CCCN1CCC1CN(C(=O)C2CCCOC2)c2ccccc21 +COc1ccc(OCC(=O)Oc2ccccc2C)cc1 +CC1CCCN(C(=O)C2CCN(C(=O)CCc3cnn(C)c3)CC2)C1 +COC(=O)Nc1ccc(CNC(=O)CSc2cccc(C)c2)cc1 +CC1CN(C(=O)c2ccc(N3CCCCC3)cc2)CC1(C)O +O=C(c1n[nH]c2ccccc12)N1CCC(C(=O)N2CCOCC2)CC1 +Cn1c(C(=O)NCCCn2cccn2)cc2occc21 +O=C(NCCCCOCc1ccccc1)N1CCCC(O)C1 +O=C(COc1cccc2ccc(=O)[nH]c12)NCc1ccccc1 +Cc1cccc(CNC(=O)c2c[nH]c3cccc(F)c23)n1 +CCOC(=O)c1ccc(-c2ccc(N)cc2Cl)o1 +CC(C)CNC(=O)c1ccc2c(c1)C(NC(=O)C(C)C)CCC2 +O=C1C(NS(=O)(=O)Cc2cccc(F)c2)CCN1c1ccccc1 +O=C(COc1ccc(F)cc1Br)NCC1CCCOC1 +O=C(Cn1nc2ccccn2c1=O)Nc1ccc2c(c1)COC2 +N#Cc1cccc(NC(=O)CCCSc2ncn[nH]2)c1 +Cc1cccc(N2CCN(C(=O)NCCCN3CCOCC3)CC2)c1 +COC(=O)c1occc1CSc1ccc(Br)cn1 +O=C(NCC(NC(=O)c1ccc(=O)[nH]c1)C1CC1)c1ccc(=O)[nH]c1 +O=C(CCNC(=O)c1ccn(-c2ccccc2)n1)Nc1ccncc1 +O=C(CCc1nc(-c2ncn[nH]2)no1)N1CCC2(CCCCC2)CC1 +CN(C)C(=O)CN(C)C(=O)CCCc1ccccc1 +CCOCc1ccc(CNC(=O)c2cn(C)nc2C(C)(C)C)cc1 +COc1ccc(NC(=O)N(C)Cc2n[nH]c3c2CCCC3)cn1 +Cc1ccc(C(N)=O)cc1NC(=O)CCCc1ccccn1 +O=C(c1ccccn1)N1CCC(c2nc(-c3ccccc3)n[nH]2)CC1 +COc1ccc(-c2ccnc(N)n2)cc1Br +CC1CCc2sc(C(=O)NC(C)CN3CCOCC3)cc2C1 +CC(C)(C)OC(=O)NC1CCN(C(=O)COCC2CCCO2)C1 +CCn1ccnc1SCC(O)CN1CCN(c2ccccc2)CC1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3cc[nH]n3)cc2F)n1 +CCc1ccccc1NC(=O)C(C)Oc1cccc(N)c1 +CCCC(=O)Oc1cc2ccccc2cc1C(=O)N1CCOCC1 +O=C(CC1C=CCC1)NCc1nnc2n1CCCCC2 +Brc1csc2snc(-c3ccon3)c12 +C=CCOC(=O)CCc1nc2sc3c(c2c(=O)[nH]1)CCC(C)C3 +Cc1nc(-c2ccc(CNC(=O)C3CCOC3)o2)cs1 +Cc1cc(CN(C)C(=O)Nc2c(Cl)cc(C)c3ncccc23)no1 +Cc1ccc(C(C)NC(=O)c2csnn2)cc1F +CC=CCn1c(NCc2ccc(C)cc2)nc2c1c(=O)[nH]c(=O)n2C +CCCc1ncc(C(=O)NCc2ccccc2)c(N)n1 +CC(=O)Nc1nnc(SCCc2ccccc2)s1 +O=C(Nc1ccncc1)N1CCCC1c1ccsc1 +CN1CCN(C(=O)c2nc3c(n2C)CCN(c2ncccn2)C3)CC1 +CC(=O)Nc1cccc(NS(=O)(=O)c2cccc(Cl)c2)c1 +CCn1nc(C)c(CCN(C)C(=O)Nc2cc(F)ccc2F)c1C +CC1(C)C(=O)OCCN1C(=O)c1c(F)cccc1Cl +O=S(=O)(Cc1nc(C2CC2)no1)c1ccc(Br)cc1 +CCCn1nc(C)c(C(=O)N2CCc3cc(F)ccc3C2)c1C +Cn1nnc2c(=O)n(CC(=O)OCc3ccccc3)cnc21 +CCOC(=O)c1ccc(NC(=O)c2csc(C)n2)cc1 +Cc1cc(C)cc(NC(=O)NCC(=O)NC2CC2)c1 +CCN(CCO)C(=O)NCc1cccnc1OC1CCCC1 +CC(OC(=O)CCn1ccccc1=O)c1nc2ccccc2s1 +O=C(CCSc1ccccn1)Oc1cccc(F)c1F +Cn1nnnc1-c1cccc(NC(=O)NC2CCCCC2)c1 +CCc1noc(CC)c1CNC(=O)C1CC1c1ccccc1F +COC(=O)c1ccc(C(=O)Nc2ccc(NC(=O)C(C)C)cc2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)NC1CCCC1(C)C +Cc1ccnc(NC(=O)C(NC(=O)C2CCCCC2)C(C)C)c1 +COc1ccccc1CN(C)C(=O)CNc1cccc(F)c1 +COCC(=O)Nc1nc2cc(Cl)ccc2n1C +CC1CCc2c(sc3ncnc(OCC(=O)N(C)CCC#N)c23)C1 +NC(=O)c1ccc(S(=O)(=O)NC2c3ccccc3CC2O)cc1 +COc1ccc(C)cc1NC(=O)CCNS(=O)(=O)c1ccccc1 +CC(C)C(CO)NC(=O)c1ccc(Cl)c(Cl)c1 +Cc1nnc(SCC(=O)c2cc3ccccc3o2)o1 +COc1ncc(NCc2cccn2C)cc1C(N)=O +CC(Cc1cccs1)NS(=O)(=O)c1ccc2c(c1)CCO2 +C#CCN(Cc1ccc(F)cc1)Cc1c(CC)nn(C)c1OC +CCCN(Cc1nc2cc(Cl)ccc2c(=O)[nH]1)C(=O)CC +CC(C)OCCCNC(=O)Cn1ncc2ccsc2c1=O +O=C(Nc1nc2c(s1)COCC2)C1COc2ccccc2O1 +CC(C)c1cc(C(=O)NCc2cccc(C(N)=O)c2)n[nH]1 +Cc1cccc(NC(=O)NC(c2n[nH]c(C)n2)C(C)C)c1 +O=C(NCC(O)Cc1ccccc1)Nc1ccc(C(F)(F)F)cc1 +N#Cc1ccc(NC(=O)CSc2nncs2)cc1Cl +Cc1csc(C(C#N)C(=O)COc2ccc(C(C)(C)C)cc2)n1 +CCOc1cc(-c2nc(-c3cccs3)n[nH]2)ccc1O +COc1cc2c(c(OC)c1OC)CCNC2C1CCCO1 +COc1ccc(C(=O)Nc2ccc3c(c2)N(C)C(=O)C(C)O3)cc1 +Cc1nc(CNC(=O)C2CC=CCC2)c(C)s1 +CN(CC(=O)OCC1CCC(=O)N1)C(=O)c1cccs1 +Cc1ccc(-c2cc(CO)nn2CCCC#N)c(C)c1 +O=C(NC1CCCC1c1ccccc1C(F)(F)F)c1ccon1 +Cc1[nH]c(C(=O)NCCc2ccc(F)cc2)c(C)c1C(=O)OC(C)C +CC(Sc1nnnn1C1CC1)C(=O)N(C)c1ccc(F)c(F)c1 +CCn1nnnc1SC(C)C(=O)Nc1cc(Cl)ccc1C +CCc1ccccc1NC(=O)CCCc1nc(-c2cccnc2)no1 +COC(=O)C(CC(C)C)NS(=O)(=O)c1ccccc1Cl +O=C(CCc1ccco1)NC1CCc2ccccc21 +COc1cc2c(cc1-c1nc3cnn(-c4ccccc4)c3[nH]1)OCO2 +O=C1COCc2[nH]c3c(Br)cccc3c21 +CCNC(=O)c1ccc(NCC(=O)Nc2ccc(F)cc2)cc1 +CN(C(=O)Cc1cn2ccsc2n1)C(c1ccc(F)cc1)C1CC1 +O=C(NC(C(=O)Nc1ccccc1)c1ccccc1)c1ccnnc1 +CC(Cn1ccnc1)NC(=O)c1cccc(NC(=O)C2CCCO2)c1 +O=C(NC1CCc2c(F)cccc21)N1CCOCC1C1CC1 +COc1ccc(Br)c(C(=O)N2CCCC2C)c1 +CCSc1cc(C(=O)Nc2ccc(N3CCOCC3)nc2)ccn1 +O=C(CCc1c(Cl)cccc1Cl)N1CCc2ncncc2C1 +COc1cc2c(cc1OC)CN(C(=O)c1cccc3ncccc13)CC2 +Cn1c(C(=O)NCCc2ccncc2)cc2c1c1ccccc1n2C +COC(=O)c1ccc2c(=O)[nH]c(CC(=O)c3cccs3)nc2c1 +COc1ccc(-c2cccc(C(F)(F)F)c2)nc1N +O=C(NC1CCc2c(F)cccc21)c1ccc[nH]c1=O +Cc1ccc(S(=O)(=O)N(C)C2(C#N)CCCC2)cc1C +CCc1cc2cccc(C)c2nc1SCC(=O)N1CCOCC1 +CC(CC#N)Sc1ccccc1NC(=O)c1ccc2nncn2c1 +CC(C)S(=O)(=O)NCC#Cc1ccc(F)cc1 +C=CCN1CCC2(CCN(C(=O)c3cccn3C)CC2)C1=O +Cc1nccnc1N1CCCC(C(=O)N2CCOCC2)C1 +CCc1nnc2ccc(NCCN3CCOCC3)nn12 +C=CCOC(=O)COc1ccc2c(C)cc(=O)oc2c1 +COC(=O)c1cc(NC(=O)c2ccc(C)cc2)c(=O)oc1C +CCCn1nnnc1COC(=O)c1cc2ccccc2[nH]1 +CCCOc1ncccc1CNC(=O)c1cnc(C2CCCO2)s1 +NC(=O)COc1ccc(NC(=O)NCc2cccnc2)cc1 +CC(Nc1ccc(Br)cc1)C(=O)N1CCCC1 +Cc1ccc(CC(=O)NC2CCN(S(C)(=O)=O)CC2)s1 +FC(F)Oc1ccccc1CNCCc1cn2ccccc2n1 +Cc1noc(CCC(=O)Nc2nc(-c3ccc(C)c(C)c3)cs2)n1 +CC(C)n1cccc1C(=O)N1CCc2ccccc2C1CO +Cc1nn(C)c(C)c1CNC(=O)c1cccc(F)c1N +Cc1ccc2c(c1)SC(C(=O)Nc1ccccn1)C2 +CC1CCN(C(=O)CSc2ccc(O)cc2)CC1 +COc1ccccc1C(=O)OCC(=O)Nc1ccccc1C +COc1ccc(-n2ccc(C(=O)N(C)C3CC3)n2)cc1 +CCc1ccccc1CNC(=O)NCc1cccc(Cn2ccnc2)c1 +O=C(c1cccc2cc[nH]c12)N1CCCN(c2nccs2)CC1 +COCCOc1ccccc1C(=O)Nc1cc(C(N)=O)ccc1Cl +CCOC(=O)c1sc(NC(=O)c2cccc(C#N)c2)nc1C +COc1ccc(C(=O)N2CCC(c3noc(N)c3C)CC2)cn1 +N#Cc1cnc(SCc2cc(=O)n3ccccc3n2)nc1N +Cc1ccc(NC(=O)C(C)n2ncc3ccccc3c2=O)cc1 +CCC(CC1CCCC1)C(=O)NCCN1CCOCC1 +O=C(CCc1ccc2c(c1)OCCCO2)N1CCCCC1CCO +COc1ccccc1C1(C(=O)N2CCN(C)CC2C)CC1 +Cn1cnc(CNC(=O)Nc2ccc(Cl)c(C(=O)NC3CC3)c2)n1 +O=c1[nH]c(N(Cc2ccccc2)Cc2ccccc2)nc2nccnc12 +O=C(NCCc1cn2ccsc2n1)c1ccc(C2CCCO2)s1 +O=S(=O)(C1CCOCC1)N1CCCCC1CO +Nc1cnc2nc(-c3ccc(C(F)(F)F)cc3)oc2c1 +CN(C1CCCCC1)S(=O)(=O)NC1CCCCNC1=O +C=CCCCN(C)C(=O)c1ccccc1N(C)C(=O)C1CC1 +CC(=O)OCC(=O)Nc1ccccc1C(=O)NCc1ccc(C)cc1 +Cc1cc(N2CCOC(c3ccc(N(C)C)cn3)C2)nc(N)n1 +CCOc1ccc(C(=O)Nc2ccccc2F)cc1OC +CCc1ccccc1NC(=O)Cn1cnc(C(=O)OC)n1 +O=C(NCC1(Sc2ccccc2)CCCC1)c1csnn1 +COc1ccc(OCC(=O)Oc2ccc3c(C)cc(=O)oc3c2)cc1 +CN(C)c1ccc(NC(=O)Cc2cccs2)nc1 +CCCCNC(=O)C1CCCN(C(=O)NCc2ccc(OC)nc2)C1 +CN(CCCNS(C)(=O)=O)c1cccc2ccccc12 +C=CCN(CC=C)C(=O)CNc1c(F)cccc1F +COc1ccnc(N2CCN(S(=O)(=O)c3cccs3)CC2)n1 +O=C(c1cccs1)C1NCCc2c(Cl)cc(F)cc21 +Cc1cc(C(=O)NC2CCOc3ccccc32)nn1C(C)(C)C +CN(C)C(C(=O)NCCc1ccncc1)c1ccc(F)cc1 +Cc1ccc(C(C#N)CCC(=O)NCC(C)C)cc1 +CC(O)c1cc(Cl)ccc1OCCCCC#N +CCN(CCC#N)C(=O)CSc1nnc(-c2cccs2)n1N +Cc1ccc(CNC(=O)CNc2cccc(C)c2C(N)=O)cc1F +Cc1csc2nc(CSc3ccc(F)cc3)cc(=O)n12 +CC(C)CC1COCCN1C(=O)CNC(=O)OCc1ccccc1 +Cc1cccc(OCC(=O)NCCCn2ncccc2=O)c1C +Cn1cc(C(=O)N(Cc2ccsc2)C2CC2)nn1 +O=C(NCc1ccnc(OC2CCC2)c1)N1CCCC1c1ccc[nH]1 +Cn1cccc1C(=O)Nc1cccc2cccnc12 +O=C(CCc1cccc(Cl)c1)OCC(=O)N1CCCC1 +COc1cccc(C(=O)N(C)CC(=O)Nc2cccc(C)c2C)c1 +N#Cc1cccc(C(=O)NCc2ccc(N3CCCC3)nc2)c1 +Cc1noc(CCCC(=O)NCC(F)(F)F)n1 +CCOCC(=O)Nc1ccc(CN2CCCC2=O)cc1 +Cc1cccc2[nH]c(CNC(=O)NCC(C)c3nccs3)nc12 +CCc1ccc(CNC(=O)NCc2ccccn2)s1 +CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1 +COC1CN(C(=O)c2cc(S(=O)(=O)N(C)C)ccc2Cl)C1 +N#Cc1ccc(Oc2ccc(NC(=O)N3CCOCC3)cc2)cc1 +CCc1ccccc1NC(=O)NC1c2ccccc2CC1O +CN(C)C(=O)COc1cc(C(=O)NC2CCCC2)nn1C +CCOC(=O)c1cnc(Cc2ccccc2C)nc1N +Cc1oc(C(=O)N(C)C2CCc3ccccc3C2)cc1S(N)(=O)=O +Nc1cc(=O)n(C2CC2)c2c1S(=O)(=O)CCC2 +CC(C)c1nc2n(n1)CCCC2NC(=O)c1cn(C)nc1C(C)(C)C +CCC(=O)N(Cc1cccs1)c1ccc(F)cc1F +CCCn1nc(-c2cc(C)sc2C)cc1C(=O)NCC1CC1 +N#Cc1ccc(NC(=O)NCC2(O)CCCCC2)cn1 +N#Cc1ccc(C(=O)Nc2cccnc2N2CCCC2)cc1 +Cn1nc(C(=O)NC2CCCCC2)c(=O)c2cc(F)ccc21 +O=C(Nc1cn[nH]c1)c1ccc(C#CCO)cc1F +CCOc1ccccc1NC(=O)N1CCN(c2ccc(O)cc2)CC1 +CC(C)C(CO)NC(=O)Nc1ncc(-c2ccccc2)s1 +O=C1CN(C(=O)c2cc(-c3ccco3)nn2-c2ccccc2)CCN1 +CCCn1nc(C)cc1NS(=O)(=O)c1ccc(OC)cc1 +COc1cc2c(cc1OC)CN(C(C)c1nc(C3CC3)no1)CC2 +CC1CN(C(=O)c2n[nH]c3ccc(N)cc23)CCO1 +CC(C)N(C(=O)c1ccc(N2CCCC2=O)cc1)C(C)C +NS(=O)(=O)c1ccc(CNc2ncnc3ccccc23)cc1 +CNC(=O)NCC(=O)Nc1ccccc1-c1nc2ccccc2[nH]1 +CCOC(=O)C(N)Cc1nc2ccc(O)cc2s1 +COc1ccc(Br)c(C(=O)N(C)Cc2ccco2)c1 +O=C(CCNS(=O)(=O)c1cccc(Cl)c1)NCC1CCCO1 +CCOC(=O)c1c[nH]c2c(Cl)cccc2c1=O +CC1CC(c2ccc(F)cc2)CN1C(=O)CCOCC1CCCO1 +CCCS(=O)(=O)Nc1ccc(OC)c(OC)c1 +CC(C(=O)NCc1cccc(CN2CCCC2=O)c1)c1cccs1 +CCc1nc(C2CCCN2C(=O)C(C)c2cc(C)oc2C)no1 +CC(C)COc1ncccc1C(=O)Nc1nccs1 +C=CCOCC1CCC2C1OCCN2C(=O)Cc1cccs1 +COCCCN(C)C(=O)Cc1c[nH]c2c(C)cccc12 +CCC(=O)OC1C(C)(C)C(OC(=O)CC)C1(C)C +CC(C)NC(=O)c1cccc2c1CCCN2CC(=O)NC1CCCC1 +O=C(COCC1CC1)NCc1nnc2n1CCCCC2 +COc1cccc2sc(NC(=O)c3cccc(C#N)c3)nc12 +CC(=O)N1CCN(C(=O)CCc2nc(-c3cccnc3)no2)CC1 +COCC(C)N1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +CCCNC(=O)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +CCCn1nnc(NC(=O)COc2ccc(OC)cc2)n1 +CCn1cnnc1CNC(=O)c1cccc(NC(=O)c2ccco2)c1 +Cc1nccn1-c1ncccc1NC(=O)c1cc2c(F)cccc2[nH]1 +COc1cc(OC)cc(C(=O)Nc2ccc(N)cc2C)c1 +CC(C)CC(=O)NC1CCCc2ccc(C(C)O)cc21 +COC(=O)c1ccc(C(=O)NCC2CCOC2)s1 +O=C(NCc1nnc2n1CCC2)c1ccc(OC(F)(F)F)cc1 +COc1ccc(F)cc1NC(=O)CSc1ccc(O)cc1 +Cc1ccc(C)c(N2CCn3c2nc2c3c(=O)n(C)c(=O)n2C)c1 +CCNC(=O)Cc1csc(NC(=O)c2ccco2)n1 +Cc1ccc(-c2ncc(C(=O)NC(C)(C)C)c(N)n2)cc1 +CCC(CC)NC(=O)C(C)Sc1nccn1C +O=C(NC1CCCCC1)C1CC2CCCC(C1)C2=O +O=S(=O)(NCCc1ccsc1)c1cccc(C(F)(F)F)c1 +CCCn1cc(NC(=O)c2c(C)cc(C)cc2C)cn1 +CCOc1cc(CNn2nnnc2N)cc(Cl)c1OC +COCCS(=O)(=O)N1CCC(C(=O)OC)CC1 +OCCCNc1ncnc2ccc(Br)cc12 +Cc1nc(Cc2nn3c(-c4ccc(F)cc4)nnc3s2)cs1 +Cn1cc(C(N)=O)c(NC(=O)c2ccc(F)cc2C(F)(F)F)n1 +COc1cc(C)cc2oc(=O)c(CC(=O)Nc3ccccn3)c(C)c12 +OC(CSc1ncnc2sccc12)c1ccccc1 +C=CCOC(=O)c1ccc(N2CCCCC2=O)cc1 +COCC(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1 +CNC(=O)Nc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 +Cc1ccc(Nc2nc(CSc3n[nH]c(N)n3)cs2)cc1 +CC(C)(C)C(O)CCNC(=O)c1ccccc1C(F)(F)F +Cn1nc(C2NCCc3cc(F)c(F)cc32)c2ccccc21 +CCOC(=O)Nc1cccc(C(=O)NC2(C(=O)OC)CCCCC2)c1 +Cc1cc(C)c(C(=O)NC(C)c2nc(C)cs2)c(C)c1 +COc1ccnc(NC(=O)c2cccc(OCc3noc(C)n3)c2)c1 +Cc1ccccc1CC(C)NC(=O)Cc1ccsc1 +CN(C)C(=O)CNC(=O)Nc1cnn(CC2CCCO2)c1 +CN1C(=O)CC(c2ccncc2)C12CCN(c1ncccn1)CC2 +COc1ccc(CN(CCO)C(=O)C2CCC2)c(OC)c1 +CCCCc1nc2cc(C(=O)NC(C)c3cnn(C)c3)ccc2o1 +N#CC(NC(=O)COc1ccccc1)c1ccncc1 +CC(C)(C)C(NC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O)C(N)=O +CCN(CCO)c1ncnc2sc(C)c(-c3ccc(OC)cc3)c12 +Cc1ccsc1C(=O)N1CCC(CCC(=O)NC2CC2)CC1 +CC(C)CC(C)N(C)C(=O)CSc1nncn1C1CC1 +CC(Cc1ccccc1F)C(=O)NCC1CN2CCCCC2CO1 +CC(=O)Nc1ccc(C#CCNC(=O)Nc2ccccc2)cc1 +COc1ccccc1N1CCN(CC(=O)Nc2ccc(F)cc2)C1=O +O=C(NCc1ccc(F)cc1)NC(c1ccccc1)c1ccccn1 +COCCCN(Cc1ccncc1)C(=O)C1CCCC1 +CCCNC(=O)C(C)NC(=O)Nc1c(CC)cccc1CC +Cc1cc2c(NCc3cccnc3)ncnc2s1 +COC(=O)C(C#N)CC(=O)c1ccc(OC)c(C)c1 +CCOc1ccccc1CN(C)S(=O)(=O)c1cccc(C(N)=O)c1 +N#CCCSc1nnnn1Cc1cccs1 +Cn1nc(CNC(=O)C(C)(C)C)cc1-c1ccccn1 +Cc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1C(F)(F)F +COCc1ncc(CN2CC(NC(C)=O)C(c3ccc(C)o3)C2)cn1 +Cn1nc(CNC(=O)CCc2ccccc2)cc1-c1ccccn1 +Cc1cccc(CNC(=O)Cc2coc(-c3ccc(Cl)cc3)n2)n1 +Cc1csc(NC(=O)c2ccc(-c3cccs3)nc2C)n1 +O=C(Nc1ccc(CCN2CCOCC2)cc1)c1ccc2cc[nH]c2c1 +Cc1ccc(CNc2ncnc(NCc3ccc(C)cc3)c2N)cc1 +CC(=O)c1cccc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)c1 +COC(=O)CCNS(=O)(=O)c1ccc(C)cc1 +CCCCS(=O)(=O)Nc1c(C)nn(Cc2ccccc2C)c1C +CN(C)c1nc2c(c(=O)[nH]1)CCN(C(=O)c1ccccc1O)C2 +N#Cc1ccccc1OCCCn1cc(Br)cn1 +CCc1ccc(OCCN2CCC(C#N)CC2)cc1 +O=C(c1cccc(F)c1)N1CC=C(c2c[nH]c3ccccc23)CC1 +COc1cccc(C(=O)N2CCC3(C2)OCCO3)c1F +COc1c(C)cnc(CNC(=O)NCCc2ccc(C)nc2)c1C +CCCC(C)(CO)NC(=O)Nc1cc(F)c(OC)cc1OC +Cc1cc(C(=O)NCC(=O)NC2CC2)c2cnn(C(C)C)c2n1 +O=c1[nH]nc2ccnc(Nc3ccc(Cl)cc3)n12 +COc1ccc(-c2cc(C(C)=O)c(C)[nH]2)cc1Cl +CC(C)CNC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CC(NC(=O)c1ccn(C)c(=O)c1)c1cc2ccccc2o1 +c1ccn2c(CCNCc3ccncc3)nnc2c1 +CC1(O)C(O)C(CO)OC1n1cc(Cl)c2c(N)ncnc21 +CCCn1c(SCCC(N)=O)nc2cc(S(N)(=O)=O)ccc21 +Cc1cc(N)ccc1NC(=O)CCCOC(C)C +O=C(NCCNc1ncccn1)c1cccc(Cl)c1 +CC(=O)c1cccc(NC(=O)c2ccc(NC(=O)C3CC3)cc2)c1 +CN(CC(=O)OCC1CC1(Cl)Cl)Cc1ccccc1 +CC(CC(=O)Nc1nnc(C(C)C)s1)NC(=O)c1ccccc1 +Cc1csc(NC(=O)CSc2cccc(N)c2)n1 +CC(Cc1nc2ccccc2s1)N(C)Cc1nccs1 +Cc1ccc(C(=O)NCCCn2cnc3ccccc32)cc1F +O=C(CCC(=O)c1cccs1)Nc1cccnc1 +COCc1ccc(C(=O)NCc2nc3ccccc3[nH]2)o1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)CC(=O)N3)cc1 +CC(C)N(C)C(=O)c1cc(-c2ccc(Br)cc2)n[nH]1 +O=S(=O)(NC1CCc2ccccc21)c1ccc(F)c(F)c1F +C#CCNc1ccc(C)c(S(=O)(=O)N(C)C)c1 +CC(Cc1ccc(C(F)(F)F)cc1)NC(=O)c1ccc(=O)n(C)c1 +CCOc1ccccc1NC(=O)C1Cc2ccccc2CN1 +CCN(C)S(=O)(=O)c1cccc(Cl)c1C#N +Cc1csc(S(=O)(=O)C(C)C(=O)NCCc2ccccc2)n1 +C=CCN1C(=O)CC2C1CCN2C(=O)c1cnccn1 +CCOC(=O)c1csc(NCc2ncc[nH]2)n1 +CC(=O)NCCNC(=O)NC1CCCC(C(F)(F)F)C1 +O=C(CCOc1ccccc1)OCC(=O)N1CCCCC1 +O=C(Nc1cccc(SC(F)F)c1)C1CCCN1C(=O)C1CC1 +Cc1cnc(C(N)=O)c(CCc2ccc(S(N)(=O)=O)cc2)n1 +O=C(Nc1ccc2nc(N3CCOCC3)sc2c1)C1CCC1 +Cc1cnn(CC2CCCN2C(C(N)=O)c2ccccc2)c1 +COC(=O)C1CCCC(=O)N1c1cc(C)ccc1C +O=C(c1ccc2cc[nH]c2c1)N1CCN(C2CC2)CC1c1ccccc1 +COc1ccc(C(=O)Nc2cccc(-c3noc(C)n3)c2)c(OC)c1 +O=C(c1ccc(OC(F)(F)F)cc1)N1CCCC1 +CCOc1ccc(CN(CC)C(=O)Nc2ccncc2)cc1OC +Cc1nc2nc(SCC(=O)Nc3nccs3)nn2c(C)c1C +COc1ccc(NS(=O)(=O)c2cccc(NC(C)=O)c2)cc1 +CCC(O)CN1CCN(C(=O)COc2cccnc2)CC1 +CNc1cccc2c(OCC(F)(F)F)ncc(C)c12 +COc1ccc(-c2cn(-c3ccc(F)cc3)c(=O)[nH]2)cc1OC +CCCS(=O)(=O)c1ccccc1NCc1ccnc(C)n1 +O=S(=O)(CC(O)CO)c1ccc(Br)cc1 +CSc1nnc(SCC(=O)Nc2ccccc2C)s1 +CCCCC(NC(N)=O)C(=O)Nc1cc(C)cc(C)c1 +CN(Cc1ccsc1)C(=O)COc1ccc(C#N)cc1Cl +CCc1cc(C(=O)Nc2cccc(O)c2)sc1C +Cc1cc(NC(=O)CC2CCCCC2)nc2nc(C(F)(F)F)nn12 +CC(=O)NCCNC(=O)Cc1csc(-c2ccccc2)n1 +O=C(Nc1ccc(Sc2nncs2)cc1)c1ccco1 +O=C(Nc1ccncc1)C1CCCN(C(=O)c2cccs2)C1 +COc1cccc(C(NC(=O)NCC2CCOC2)c2nccn2C)c1 +CC(C)CCOc1ccc(C(=O)NCc2cccnc2)cc1 +CCCNc1nc(-c2c(C)oc(C)c2C)cs1 +CC(C)c1n[nH]c(C2CN(C(=O)c3ncoc3C(C)C)CCO2)n1 +CCC(C)n1ncc2cc(Br)cnc21 +C=CCNC(=O)c1ccc(NC(=O)N(C)Cc2ccccc2C)cc1 +COc1ccc(C(=O)N(C)Cc2nccn2CC(F)(F)F)c(F)c1 +Cc1cc(=O)n(CC(N)=O)c(-c2ccc(F)cc2)n1 +CC(NC(=O)N(CCO)C1CC1)c1ccc(-c2cncnc2)cc1 +CCc1ncc(NC(=O)N2CCCC(c3nncn3C3CC3)C2)cn1 +O=C(c1cn[nH]n1)N(CCc1ccc(Cl)cc1)CC1CC1 +O=C(CCNC(=O)c1ccoc1)NCc1ccccc1 +O=C(NCC#CCN1CCOCC1)Nc1cccc(Cl)c1 +Cc1nccnc1OCCC1CCN(C(=O)OC(C)(C)C)CC1 +Cc1csc(C(C)NC(=O)c2cnn(-c3ccc(F)cc3)n2)n1 +Cc1nc(-c2ccsc2)ccc1C(=O)N1CCN(C(=O)CO)CC1 +O=C(NCCCC(=O)N1CCCC1C1CCCC1)c1ccco1 +COc1cc2c(c(OC)c1OC)C(C1CC(=O)C1)NCC2 +C#CCOC(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +CNC(=O)NCc1ccc2c(c1)N(C(=O)c1cccc(C)c1)CC2 +Cn1cc(NC(=O)CN2C(=O)CSc3ccccc32)cn1 +O=C(Nc1cccc(Cl)c1)C1CC(=O)N(C2CCCC2)C1 +CCOc1cn(-c2ccccc2)nc1C(=O)Nc1cc(F)ccc1F +CNC(=O)COC1COC2(CCN(c3ncccn3)C2)C1 +CCC(CC)C(=O)NCCc1nc2cccnc2n1-c1ccccc1 +Cc1nc(C)c(C(=O)Nc2ccc3c4c(c(=O)[nH]c3c2)CCC4)s1 +CCN(CC)C(=O)c1ccc(F)c(S(=O)(=O)NC(C)C)c1 +CSc1ccc2nc(NC(=O)c3nn(C)cc3C)sc2c1 +CCS(=O)(=O)c1ccc(CCC(=O)OC)cc1 +O=C(c1cccc(Cl)c1)N1CCOCC1CO +N#Cc1cc(F)ccc1NC(=O)NCC1Cc2ccccc2O1 +CCOCC(=O)N1Cc2nn(C(C)(C)C)c(-n3cccc3)c2C1 +Cc1c(C(=O)N2CCC3(CCCCC3)CC2)cnn1-c1ccncc1 +Cc1cccc(C)c1OCCNC(=O)NCc1ncn(C)n1 +COC(C)(C)c1noc(C(C)c2ccc3c(c2)OCCO3)n1 +CCOC(=O)c1nnn(-c2nonc2N)c1CNc1ccccc1 +O=C(Cc1ccccc1F)NCCOc1ccccc1 +Cc1ccc(S(N)(=O)=O)cc1NC(=O)COc1ccccc1 +COCCCNC(=O)CS(=O)(=O)c1ccccc1Cl +COc1cccc(C(=O)n2nc(-c3ccccc3)nc2N)c1 +CC(C)CNC(=O)N1CCCC(C(=O)NC(C(N)=O)C(C)C)C1 +Cc1cccc(C(=O)N2CC(S(=O)(=O)c3ccc(F)cc3)C2)c1 +CCCOc1cccc(NC(=O)c2c(C)cc(C)[nH]c2=O)c1 +CC(Nc1ccc(=O)n(C)c1)c1ccc(F)cc1Cl +COC(=O)CCc1c(C)nc(-c2ccc(C(F)(F)F)cc2)[nH]c1=O +Cc1csc(C2CN(C3CC(C)OC3=O)CCO2)n1 +NC(=O)c1cncc(CCCCOc2ccccc2)c1 +Cc1[nH]ncc1CCCNC(=O)NCCC1=CCCCC1 +O=C(NCc1nnc2ccccn12)c1cc(F)cc2[nH]cnc12 +CN(Cc1ccccc1F)C(=O)COc1ccccc1C#N +O=C(c1ccc(F)c(F)c1)N1CC(c2nc(-c3ccccn3)no2)C1 +COc1ccc(CN(C)C(=O)c2cccc(N)c2)cc1 +CN1CC(C(=O)N2CCCC3CCCC32)CC1=O +O=C(c1sccc1-c1ccc(F)cc1)N1CCOCC1 +COC(=O)C(NS(=O)(=O)N(C)C)C(C)(C)C +CCOC(=O)C1C(=O)C(=O)N(C)C1c1ccccc1 +COc1ccc(CCNS(=O)(=O)c2cnn(C)c2)cc1OC +CN(c1ccccc1)C1CCN(C(=O)c2cc[nH]n2)CC1 +CC(NC(=O)CCC(=O)c1ccc2c(c1)CCC2)c1ccccn1 +COC(=O)C(C)Sc1nc(Cc2ccccc2)c(C)[nH]1 +CC(=O)c1ccc(NC(=O)c2cc(C)nc3onc(C)c23)cc1C +CCCC(=O)NCC(=O)NCc1sccc1C +CCCCn1nc(C(=O)Nc2cc(OC)c(OC)cc2C)ccc1=O +Cc1ccccc1NC(=O)c1csc(CC(C)C)n1 +CC(C)(C)c1ccc(C2(C(=O)Nc3cn[nH]c3)CC2)cc1 +COCc1oc(-c2cc(F)ccc2OC)cc1CO +O=C(NC1(c2ccc(Cl)cc2)CCOCC1)C1CCC1 +CC(C(=O)N1CCN(c2ccccc2)CC1)c1cccs1 +CNS(=O)(=O)c1cc(C)c(C)cc1Br +CC1Cc2ccccc2N1CC(O)COCc1ccco1 +Cc1ncc(CN(C)C(=O)c2ccc3c(c2)OCO3)s1 +O=C(NCC1COCCO1)Nc1cccc(F)c1F +CN1CCN(S(=O)(=O)c2cn(C)c(=O)n(C)c2=O)CC1 +C=C(C)Cn1c(SCC#N)nc2ccccc2c1=O +CCc1ccccc1NC(=O)CC1NC(=O)c2ccccc2NC1=O +Cn1ccnc1Cn1c(C(C)(C)C)nc2cccc(F)c21 +CCOc1ccc(S(=O)(=O)N(CC)CC)cc1C(N)=O +CCS(=O)(=O)N(C)CCCNC(=O)c1cccc2c1OCCO2 +CC(NC(=O)CNC(=O)NC1CC1)c1ccc(Br)cc1 +COC1CCC(c2oc3ccc(C)cc3c(=O)c2O)CC1OC +O=C(NCC(O)c1ccc(Cl)cc1Cl)NCC(F)(F)F +CCNC(=O)c1cccc(S(=O)(=O)N2CCN(C)CC2)c1 +C=CCSc1nnc2n1CCN2c1ccc(OC)cc1 +O=C(Nc1ccc(N2CCOCC2)nc1)c1cccc2cccnc12 +Cc1cnn(CC(=O)N2CCN(CC(O)C(C)(C)C)CC2)c1 +CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1cc(F)ccc1O2 +Cc1csc(S(=O)(=O)Cc2noc(C(C)(C)C)n2)n1 +NC(=O)CCSc1nnc(-c2cccc(Cl)c2)o1 +Cc1ncsc1CN1CCN(C(C)C(=O)N2CCOCC2)CC1 +CC(Oc1ccc(F)cc1Cl)C(=O)N(C)Cc1ccncc1 +CCNC(=O)COc1ncnc2scc(-c3ccc(C)cc3)c12 +CCN(C(=O)CCCc1nc(C)no1)C(C)c1ccc(C#N)cc1 +O=C(NCc1ccncc1)NCc1cccc(COc2ccccc2)c1 +CN(Cc1ccccn1)C1COC2(CCN(Cc3cnn(C)c3)C2)C1 +Cc1nn(C(C)C(=O)NC2CCCCC2)c(=O)c2cc3occc3n12 +Cc1ccc(-c2cn(CC(=O)Nc3cccc(C)c3)c(=O)o2)cc1 +Cc1ccc(C(=O)NCC(O)c2ccc(F)c(C)c2)cc1 +COc1ccc(OC)c(C(C)NC(=O)CNC(=O)C(C)(C)C)c1 +COc1ccc(CCCCC(C)(C)O)cc1NC(C)=O +CCOc1ccc(C(C)NC(=O)c2cccc3cccnc23)cc1 +CCC(C)NC(=O)NCc1ccc(OC)c(OC)c1 +O=c1oc2cccnc2n1Cc1nc(-c2ccccn2)no1 +Cc1c(C(C)NS(N)(=O)=O)oc2ccc(F)cc12 +N#Cc1c(N2CCCC2)nsc1-c1cccnc1 +CN(C)C(=O)N1CCC(C(=O)N2CCN(c3ccccc3)CC2)CC1 +CN(C)C(=O)Cc1csc(N2CCCC2=O)n1 +CCc1ccsc1C(=O)NCCNC(=O)c1ccc(F)cc1 +CC(=O)N1CC(c2nc(C)cc(Cc3ccccc3F)n2)C1 +CN(Cc1ccccc1Br)C(=O)CN1CCOCC1 +CCc1ccc(-n2ccc(=O)c(C(=O)Nc3nnc(C)s3)n2)cc1 +O=C(NC1CC2C(=O)NC(CO)C(=O)N2C1)c1ccc(Cl)cc1 +CCC(=O)c1ccc2c(c1)N(CC(=O)OCC(C)C)C(=O)C(C)(C)O2 +COc1ccc(SCC(=O)N(C)CC(=O)NC(C)C)cc1 +CCc1ccc(S(=O)(=O)N2CCC(C#N)CC2)cc1 +CCc1nnc(COc2c(F)cc(Br)cc2C(C)=O)o1 +CN(Cc1cccs1)C(=O)c1nnc2ccccc2n1 +Cc1nc(CNC(=O)Nc2cccc(N(C)C(C)C)c2)c(C)s1 +Cc1cc(-c2cc(C#N)nn2CCO)ccc1Cl +CC1CN(C(=O)NC2CCN(S(C)(=O)=O)CC2)CC(C)O1 +O=C(NC1CCCC1)c1ccn(COc2ccc(F)cc2)n1 +C=CCOC1CCCN(C(=O)c2ccc(Cl)cc2)C1 +CNC(=O)Cn1nc(C#N)cc1-c1cccc(Cl)c1 +CCCNC(=O)C(C)Sc1nnc2n1CCCCC2 +NC(=O)CSc1nc2ccccc2n1C(F)F +Cn1nc(C(=O)N2CCCc3ccc(F)cc32)c2ccccc2c1=O +O=C(NCc1ccc(F)cc1)NCC(O)(c1ccccc1)C1CC1 +Cn1ccnc1SCC(=O)Nc1ccc(Cl)cc1Cl +Cc1cc(C)n(-c2ccc(NCc3noc(C(C)C)n3)cc2F)n1 +COc1ccc2nc(NC(=O)Cc3ccc4c(c3)OCO4)sc2c1 +Cc1ccc(NC(=O)N(C)CCC(C)O)c(OCC2CCCO2)c1 +COCCOc1cccc(CN2CCOC(C)C2C)c1 +Cn1nnc2cc(-c3noc(CNC(=O)c4ccccc4)n3)ccc21 +Cn1cc(NC(=O)C2(c3ccc(F)cc3)CCOCC2)cn1 +Cc1cccc(-c2ccc(C(=O)NCCNc3ncccn3)c(=O)[nH]2)c1 +COCCNC(=O)c1cc2c(ccc3ccccc32)o1 +COCCOc1cccc(NS(=O)(=O)c2ccc(C)c(F)c2)c1 +Cc1ccc(C(=O)N(C)Cc2csc3ccccc23)c(=O)[nH]1 +C=CCN(CC=C)C(=O)c1ccc(-n2nc(C)cc2C)cc1 +Cc1ccccc1C1CC(C)N(C(=O)CCc2c(C)nn(C)c2C)C1 +COc1coc(Cn2c(=O)oc3ccc(Cl)cc32)cc1=O +COCCn1c(SCC(=O)NC2CC2)nc2ccccc21 +CCOc1ccc2ncc(C#N)c(NCc3ccc4c(c3)OCO4)c2c1 +CC(Oc1ccccc1C(F)(F)F)C(=O)N(C)C(C)CC#N +CCc1nc(CC(=O)Nc2ccccc2Cn2cncn2)cs1 +C=CCNC(=O)c1ccc2c(c1)N(C)C(=O)CS2 +COc1ccc(C(C#N)N(C)C(C)C(O)c2ccccc2)cc1 +CCC(C)C(NC(=O)c1cc(OC)cs1)C(N)=O +CC(C)C(=O)Nc1ccc(N)cc1Br +CCc1cc(NC2CCCCC2O)nc(N(C)C)n1 +O=C(Nc1cccc(Cn2cccn2)c1)Nc1ccccn1 +CC(C)CC(NC(=O)c1n[nH]c2ccccc12)c1ccccc1 +CCOC(=O)CN(C(=O)Cc1ccc(O)cc1)C(C)C +CC(=O)NCc1ccc(S(=O)(=O)Nc2ccc(C)c(C)c2)cc1 +COC(=O)C(Nc1nc(C(C)C)nc2c1cnn2C)c1ccccc1 +COc1c(Cl)ccc2c1C(c1cc[nH]c(=O)c1)NCC2 +COCCOc1ccccc1NC(=O)c1ccnc(SC)c1 +NS(=O)(=O)NCCc1c(Cl)cccc1Cl +CC(=O)Nc1ccc(F)c(NC(=O)COCC(F)(F)F)c1 +COCC(C)Nc1nc(-c2cc(C)n(-c3cc(C)on3)c2C)cs1 +COCCC(=O)N1CCC2(CCN(c3ncccn3)CC2)C1 +CC(=O)N1CCCN(C(=O)Cc2cn(C)c3ccccc23)CC1 +CCN1CCN(S(=O)(=O)c2cc(-c3nnc(C)o3)cs2)CC1 +C=CCC1(CC=C)CCN1C(=O)c1sc2ncn(C)c(=O)c2c1C +Cc1ccncc1NC(=O)NCc1ccnc(OCc2ccccc2)c1 +O=C1C2CCCN2C(c2cccnc2)N1c1cccc(Cl)c1 +CCCC(O)CNS(=O)(=O)Cc1ccccc1C +Cc1ccc(OCC(=O)NCC(O)c2ccco2)c(C)c1 +COc1ccccc1CN(CCO)C(=O)c1ccc(C)c(F)c1 +NC(=O)C1CCN(C(=O)COc2ccc(-c3ccccc3)cc2)CC1 +Cn1c(Oc2ccc(F)cc2)cc(=O)n(C)c1=O +Cc1[nH]nc(C(N)=O)c1NC(=O)C(C)NC(=O)c1ccc(Cl)cc1 +CCCCNC(=O)c1cnc2scc(C)n2c1=O +CC(C)Cn1ncc(C(=O)NCCS(N)(=O)=O)c1C(F)F +NC(=O)CN1CCN(C(=O)c2cccc(OCC(F)F)n2)CC1 +Oc1cc(F)c2c(c1)C(C(O)c1ccccc1)NCC2 +Cc1cccc(COc2ccccc2OCCO)c1 +C=CCN(CC(=O)NC1CCCC1)C(=O)c1csnn1 +Cc1ccc(NC(=O)C(C)OCC2CCCO2)c(Cl)c1 +CCCCC(=O)NCC1(c2ccc3c(c2)OCO3)CCOCC1 +CC(NC(=O)C1Cc2ccccc2C(=O)O1)c1ccncc1 +Cc1cc(C)n(-c2ccc(-c3noc(CCc4cnn(C)c4)n3)cn2)n1 +Cc1ccnn1-c1ccc(C(=O)N2CCN(C(=O)C3CC3)CC2)cc1 +COCC(C)OC(=O)c1cc2ccccc2s1 +COCCNC(=O)N1CCN(c2ccc(Cl)cn2)CC1 +Cc1c(NCc2ccccc2)ccc2nc(N)nn12 +Cc1cc(NC(=O)C2(C)Oc3ccccc3NC2=O)c2ccccc2n1 +CC(C)CC(NC(=O)Nc1ccncc1)C(=O)N(C)C +COc1cccc(C(=O)N(Cc2ccc(F)cc2)C2CC2)c1O +COCc1cccc(C(=O)N2CCCC2CN2CC(C)OC(C)C2)c1 +Cc1cccc(CS(=O)(=O)Nc2cccc(F)c2)c1 +Fc1cccc2c(Br)cnc(N3CCOCC3)c12 +CCCCn1c(SCc2cc(C)no2)n[nH]c1=O +COC(=O)Cc1cc(=O)c2cc(Cc3ccncc3)ccc2[nH]1 +CS(=O)c1ccc(CNCC2(O)CCCc3ccccc32)cc1 +COCc1ccc(CNC(=O)C(C)Sc2ccccn2)cc1 +c1ccc(Cn2cc(NCCCN3CCOCC3)cn2)cc1 +CC(=O)c1ccc(OCC(O)Cn2cnc(C3CCC3)cc2=O)cc1 +O=C(OC(C(=O)NCC1CCCO1)c1cccnc1)c1cccs1 +CCc1ccc(C(=O)NCC(=O)N2CCCC2)s1 +COCCNC(=O)C1CCN(c2ccc(C)cc2)C1=O +COc1cc(C)c(C(=O)N(CC(F)(F)F)C2CCCC2)cc1OC +Clc1ccc(C2CN(CCc3ccccn3)CCO2)cc1 +COc1ccc(C(C)NS(=O)(=O)c2ccccc2F)cc1OC +O=C(NCc1ccc(OCc2cccnc2)cc1)C1CC2CCC1O2 +CC(C)(O)CN1CCN(C(=O)Nc2ccc(OC(F)F)cc2)CC1 +COc1cc(C(C)(O)C2OC(=O)CC2C)oc(=O)c1C +Cc1oc(-c2ccccc2)nc1CC(=O)N1CCN(C(=O)CO)CC1 +O=C(NCCc1cnn(-c2ccccc2)c1)c1c[nH]c2cccc(F)c12 +CC(C)CNC(=O)NCc1ccc(S(=O)(=O)NC2CC2)cc1 +O=C(CCc1ccccc1)Nc1ccc(CC(=O)N2CCCC2)cc1 +Fc1ccccc1CNc1ncnc2c1cnn2-c1ccccn1 +CS(=O)(=O)N(Cc1ccc(F)cc1)c1ccc(C(N)=O)cc1 +CCC(CO)NC(=O)NC(C)c1ccc2c(c1)OCO2 +Cc1nn(-c2ccccn2)c(C(F)(F)F)c1C#N +CC(=O)c1cc(CC(=O)NCc2ccc(C)c(F)c2F)cs1 +CN(c1cccc(C(=O)NC2CCCCC2)c1)S(C)(=O)=O +COCCn1ccc2c(C(=O)NC3CCOC(C)(C)C3)cccc21 +Cc1cccc(OCCNC(=O)c2ccc(-n3cncn3)cc2)c1 +O=C(c1cccc(-n2cccn2)n1)N1CCCC(N2CCCC2=O)C1 +O=C(C1CCCC1)N1CCC(Oc2cc(N3CCCCC3)ncn2)C1 +O=C1CN(C(=O)COc2ccc(-c3ccccc3)cc2Cl)CCN1 +COc1cccc(CNC(=O)c2ccc(C)cc2C)c1 +Cc1noc(-c2ccnc(NCc3cccc4c3OCCO4)c2)n1 +O=C1CC(C(=O)NCc2ccc(Cn3ccccc3=O)cc2)C1 +CC(=O)Nc1ccc(NCc2ccccc2OCc2cccnc2)cc1 +CNc1nc(C)cc(-c2cnn(CC(=O)Nc3cc(C)nn3C)c2)n1 +Cc1cc(C)cc(Nc2cc(N)nc(C3CC3)n2)c1 +CCOCc1ccc(CNC(=O)c2ccn(C)c(=O)c2)cc1 +Cc1sc2[nH]c(SCC(=O)N3CCCCC3)nc(=O)c2c1C +CCc1cc2c(=O)n(CC)c(SC(C)C#N)nc2s1 +CC(NC(=O)c1cnccn1)c1ccc2ccccc2c1 +CCc1nnsc1C(=O)NC1CCc2c(Cl)cccc21 +O=C(c1cc(F)cc2[nH]cnc12)N1CCc2ccccc2C1CO +CCN(CC)C(=O)c1ccc2nc(-c3ccc(C)cc3)cn2c1 +NC(=O)CCN(C(=O)C1CCCO1)c1ccccc1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1ccc(C)nc1 +CCOC(=O)C1CCN(C(=O)c2coc3ccccc3c2=O)CC1 +O=C(COC(=O)C(O)(c1ccccc1)c1ccccc1)N1CCCC1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccc(C#N)cc1 +CCC(Oc1ccccc1C)C(=O)N1CCN(CC)CC1 +COc1cccc(Cl)c1-c1ccc(C(=O)N(C)C)cc1 +O=C(CNC(=O)NCC(F)(F)F)Nc1cccc(F)c1 +O=C(CNc1ccccc1)Nc1ccccc1S(=O)(=O)C(F)F +Cc1cc(C)n2nc(SCc3cc(-c4cccs4)on3)nc2n1 +COc1ccccc1C(O)c1ccc2c(c1)C(C)(C)C(=O)N2 +Cc1ccccc1CS(=O)(=O)Nc1ccc2nncn2c1 +Cc1cc(C)cc(N2CC(C(=O)N3CCCCC3)CC2=O)c1 +COC(=O)N1CC2(C)CN(C(=O)OC)CC(C)(C1)C2=O +CCN1CCOC(=O)C1CC(=O)Nc1ccc(F)c(Cl)c1 +Cc1ccc2oc(C(=O)N(C)CC3CCC3)cc2n1 +Cc1cc(C)n(CCCNC(=O)Nc2ccncc2)n1 +CC1=CCC2CN(C(=O)c3ccc4ncccc4c3)CC2C1 +Cc1ccc(C(=O)N2CCc3ncnc(-c4ccccc4)c3CC2)o1 +Cc1ccc2ncc(C(=O)Nc3ccc(F)c(C(=O)N(C)C)c3)n2c1 +CCOc1cccc2cc(C(C)NC(=O)c3cccnc3)oc12 +O=C(CCn1ccc2ccccc21)N1CCCC(O)C1 +COc1ccc(Cl)cc1C(=O)N(Cc1ccco1)C1CCOCC1 +CC(OCC(F)(F)F)C(=O)Nc1ccc2c(c1)OCCO2 +CC(C)COc1ccc(NC(=O)N2CC3CC(O)C(O)CC3C2)cc1 +COC(=O)CCCC(=O)NC1CCCc2nc(N(C)C)ncc21 +O=C(CCNC(=O)c1ccoc1)Nc1nccs1 +CC(=O)N1CCOC2CCN(C(=O)Cc3ccsc3)CCC21 +Cc1nc(C)c(C(=O)NCC(O)COc2ccc(F)c(F)c2)o1 +Nc1cc(NC(=O)CCCc2cccs2)ccc1F +O=C(CSc1cccs1)Nc1ccc(N2CCCCC2)nc1 +COC(=O)c1ccn(-c2nc(C3CC3)cc(C(F)(F)F)n2)n1 +C=C(C)CN(CC)S(=O)(=O)c1ccc(OC)cc1C +CCn1c(SCc2nnc(C3CC3)o2)nnc1-c1ccccc1 +CCSc1cc(C(=O)Nc2ccc(Br)cn2)ccn1 +C#CCN1CCN(C(=O)NCCN2c3ccccc3CC2C)CC1 +CCOC(=O)N1CCC(C(=O)OCc2cc(-c3ccco3)on2)CC1 +Cc1c(C)n(Cc2cccs2)c2ncnc(N)c12 +NS(=O)(=O)c1ccc(NCc2nc3ccccc3[nH]2)cc1 +O=C(OCC(=O)N1CCCC1)c1ccc(OC2CCCC2)cc1 +COC(=O)C1CCN(C(=O)Cc2csc(NC(C)=O)n2)CC1 +CCOc1cccc(C(=O)Nc2sc(CC)cc2C#N)c1 +COC(=O)c1ccc(CN(C)C(=O)c2cc(C)no2)cc1 +Cc1noc(C(C)N2CCN(CCOc3ccc(C#N)cc3)CC2)n1 +Cc1nc(NCc2ccco2)cc(-c2cncc(-c3cccs3)c2)n1 +N#Cc1ccc(CCC(=O)N(CCC(N)=O)c2ccccc2)cc1 +Cc1nc2ccc(NS(=O)(=O)c3ccccc3Cl)cc2o1 +CCN(CCNC(=O)c1ccc(F)nc1)C(=O)OC(C)(C)C +CCC(C)NS(=O)(=O)c1ccccc1C(=O)OC +COc1ccccc1N1CCN(c2ccc3nc(N)nn3c2C)CC1 +COc1cc(C(=O)NCC(F)(F)F)ccc1OCC(N)=O +Cc1cscc1C(=O)N(C)c1cccc2ncccc12 +CCOC(=O)NCCC(=O)N1CCCC1c1ccc(C)c(C)c1 +O=c1cc[nH]c(C2NCCc3c2ccc(F)c3O)c1 +Cc1ccc(CN(C)C(=O)c2ccc(Cl)cc2O)o1 +CC1CC(C)CN(C(=O)c2ccc(=O)n(-c3ccccc3)c2)C1 +Cc1nn(C(C)(C)C)c(=O)n1CC(=O)Nc1cc(Cl)ccc1F +CC(NCc1ccc(S(N)(=O)=O)cc1)C(=O)NC1CCCC1 +Cc1cc(C(=O)Nc2sccc2C(N)=O)n(C(C)C)n1 +Cn1c(C(=O)NCC2CCCO2)cc2ccc(Cl)cc21 +CC(=O)c1ccc(OC(=O)c2ccccc2-n2cnnn2)cc1 +CNC(=O)CNC(=O)C(C)Oc1ccc(F)c(F)c1 +NC(=O)c1cccc(NC(=O)CNc2ccc(Cl)c(Cl)c2)c1 +CN1C(=O)c2ccccc2N2C(=O)CCC12C(=O)NCc1ccccc1 +Cc1cc(=O)c(C(=O)Nc2nnc(C=Cc3ccco3)s2)c[nH]1 +CCOCCC1CCN(C(=O)c2cc(F)ccc2O)CC1 +N#Cc1cccc(C(=O)N2CCC(CN3CCOCC3)CC2)c1 +COCCNC(=O)C1CN(Cc2ccccc2)CCO1 +COc1cc(-c2cc(C(C)=O)on2)cc(OC)c1OC +CCCOc1ccccc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +CCN(CC)C(=O)CCC(=O)Nc1n[nH]c(-c2ccc(C)cc2)n1 +O=C(Nc1ccc(OC(F)F)c2ncccc12)N1CCCC1 +Cc1sc2nc(-c3nc4c([nH]3)CC(C)(C)CNC4=O)cn2c1C +Cc1noc2nc(C(C)C)cc(C(=O)N3CCCC(C)C3)c12 +COCCN1CC(C(=O)NC(C)c2ccncc2)CC1=O +C=CCN1CC2(CCN(C(=O)c3cc(C)on3)CC2)OCC1=O +O=C(Oc1cccc(NC(=O)C2CC2)c1)c1cccc(-n2cnnn2)c1 +COc1ccc(C(=O)Nc2nnc(-c3ccnn3C)o2)cc1OC +COCc1nc2cc(NC(=O)c3cc(C#N)c[nH]3)ccc2o1 +COc1c(CNC(=O)NCc2c(C)cc(C)cc2C)c(C)nn1C +CCNC(=O)c1csc(Nc2cccc(C)n2)n1 +Cc1nc(Cc2nnc(SCC(=O)NC(C)C)o2)cs1 +Cc1nonc1C1CCCN1C(=O)c1cccc(-n2cccn2)c1 +Cc1nc(C(=O)N(C)c2nc3ccccc3s2)cs1 +CCC(C)NC(=O)c1ccc(N(C)S(C)(=O)=O)cc1 +CCc1ccc(N(Cc2ccc(C)s2)C(=O)CNC(=O)NC)cc1 +CCCc1nn(-c2ccccc2)c(C)c1C(=O)NC(C)C +COC(=O)c1cc(CNC(=O)c2ccccc2O)ccc1OC +Cc1n[nH]c(C2CC3CCN(C(=O)c4cscn4)CC3O2)n1 +O=C(NC1CCCCCC1)c1cnc(C2CCCO2)s1 +CCc1c2c(nc3cc(C(N)=O)n(C)c13)CC(C)(C)CC2=O +Cn1ccc(C(=O)NC(C)(C)c2cccc(Cl)c2)cc1=O +CCOC(=O)CC(NC(=O)c1ccc(F)cc1)c1ccccc1Cl +COC(=O)CNc1nccc2c(N)ccc(Cl)c12 +Cc1sc(=O)n(CCC(=O)Nc2nncs2)c1C +CC(=O)c1cccc(NC(=O)CSc2ncccc2C#N)c1 +CCCc1cc(=O)n2nc(C)c(-c3ccccc3OC)c2[nH]1 +CCOc1cccc2cc(C(C)NC(=O)CCn3cc(C)cn3)oc12 +Cc1csc(NC(=O)c2ccc(Cl)c(S(C)(=O)=O)c2)n1 +COC(=O)C(Cc1ccc(OC)c(F)c1)NC(C)=O +COC(C)C(=O)Nc1cc(-c2nnc3n2CCCCC3)ccc1F +CC(C)N(C)c1ccc(NC(=O)CC2CCCO2)cc1F +CC(C)Oc1ccc(C#N)cc1NC(=O)N(C)C(C)c1ccccn1 +COC(C)(C)Cn1ccnc1-c1cnc2cc(O)ccc2c1 +CCNC(=O)c1cc(S(=O)(=O)NCC)ccc1OC +CCc1cc(=O)n(CC(=O)N2CCOCC2)c(-n2nc(C)cc2C)n1 +CCOC(=O)C1(NC(=O)c2ccc(C)o2)CCCC1 +CCN(CC)C(=O)c1c[nH]c2nc(-c3ccccc3)ccc12 +O=C(CCn1ncc(=O)c2ccccc21)N1CCCCc2ccccc21 +NC(=O)CCN(C(=O)COc1ccc(Cl)cc1)c1ccccc1 +Cc1cc(=O)[nH]c(N2CCN(c3cccc(Cl)c3)CC2)n1 +C#CCOCC1CCCN(C(=O)c2ccc(N(C)C)cc2)C1 +O=C(NC1CC(=O)N(c2ccc(Cl)cc2)C1)N1CCC(O)CC1 +COc1cc(N)c(C(=O)Nc2ccccc2)cc1OC +CCn1c(=O)[nH]c2cc(C(=O)N(C)CC(O)C3CC3)ccc2c1=O +Cc1ccc(CNC(=O)CN2CCOC(Cn3cccn3)C2)s1 +CCOc1cccc(NC(=O)Nc2ccncc2C)c1 +CCOc1ncccc1NC(=O)N1CCC(CNC(C)=O)CC1 +CC(C)N(C(=O)c1cnn(-c2ccccc2)c1)c1ccccc1 +CCNC(=O)c1ccc(NC(=O)Cc2ccc(F)cc2F)cc1 +Cc1ccc(N2CCN(CC(=O)NCC(N)=O)C2=O)cc1 +Cc1ccccc1NC(=O)Cn1nc(C(=O)N2CCCC2)ccc1=O +CC(NC(=O)c1cnn(C)c1)C(=O)NC(C)(C)C +CN(CC(=O)NC1CC1)C(=O)CSc1nnnn1C1CC1 +COC(CNS(=O)(=O)c1c(F)cccc1F)c1cccc(F)c1 +NC(=O)CN1C(=O)COc2ccc(C(N)C(F)(F)F)cc21 +CC(c1ccccc1)N1CCN(C(=O)c2cc(F)c(F)cc2F)CC1 +CN(CC(=O)Nc1ccc(Cl)cc1)S(=O)(=O)c1cccs1 +Cc1cccc(C2CC2C(=O)N2CCCC(n3nc(C)cc3C)C2)c1 +Nc1ncc(C(F)(F)F)cc1N1CCN(c2ncccn2)CC1 +CC1CCCC(NC(=O)CN2CCN(C(=O)c3cc[nH]n3)CC2)C1 +COC(=O)C(NC(=O)c1cccc2[nH]ccc12)c1cc(F)ccc1F +CN(Cc1nc(-c2cccnc2)no1)C(=O)C1CCCc2ccccc21 +O=c1[nH]c2ccccc2n1CCc1ccc(F)cc1 +CCOc1cccc(NC(=O)NCc2ccccc2OC)c1 +C#CCN1C(=O)C(CC)(CC)Oc2cc(N)ccc21 +CN(C)c1ccc(C2CCN(C(=O)c3ccn(C)n3)CC2)nc1 +CC1COC(CO)CN1C(=O)Nc1ccc2c(c1)COC2 +CCC(C)C(=O)Nc1ccc(S(=O)(=O)CC2CCCO2)cc1 +COCc1ccc(C(=O)OCc2cnn(C)c2)o1 +Cc1ocnc1CNS(=O)(=O)c1ccc(F)cc1Cl +Cc1n[nH]c(C)c1S(=O)(=O)N(Cc1ccccc1)c1ccccc1 +CS(=O)(=O)NC1CCN(C(=O)c2ccccc2F)CC1 +CN(CCO)S(=O)(=O)c1c[nH]c2ccccc12 +O=C(Cn1c(=O)cnc2ccccc21)OC(C1CC1)C(F)(F)F +CN(c1ccccc1)S(=O)(=O)c1cccc(C(=O)NCCO)c1 +Cc1ocnc1CNS(=O)(=O)Cc1c(Cl)cccc1Cl +CSc1cccc(NC(=O)Cc2c(C)noc2C)c1 +COc1ccccc1C(=O)Nc1ccc(N2CCCC2=O)c(C)c1 +COc1c(Cl)c2c(c(OC)c1OC)CCNC2C +Cn1cc(N2CCN(Cc3ccc(Cl)c(F)c3)CC2=O)cn1 +COC(=O)C(c1ccc(F)c(Br)c1)N(C)C +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccccc1 +CN(CC(=O)NC(C)(C)C)S(=O)(=O)c1ccc(Cl)cc1 +COC1CCCC(OC(=O)c2ccc(F)c(F)c2)C1 +CC1CCCC(C)N1S(=O)(=O)c1ccc(N2CCCC2=O)cc1 +O=C(CCO)N1CCN(c2ncnc3sccc23)CC(O)C1 +CCOC(=O)c1nnc2c(-c3ccc(F)cc3)c(COC)nn2c1C +CC(C)c1cc(C(=O)N2CCCC2C(C)C)c2cnn(C(C)C)c2n1 +Cc1noc(C)c1S(=O)(=O)N1CCCC1C(=O)Nn1cnnc1 +O=C(NC1(c2ncon2)CCOCC1)c1cc(-c2ccccc2)[nH]n1 +CCN(CC)S(=O)(=O)c1ccc(NCc2c(C)noc2C)cc1 +CCN(Cc1ccccc1C)C(=O)c1scnc1C1CC1 +CC(C(=O)Nc1ccc2c(c1)OCO2)n1nnc(-c2ccccc2)n1 +CC(C)NCC(=O)OCc1ccc2c(c1)CCC(=O)N2C +CCN(C(=O)Cc1cccc(O)c1)C(C)COC +Cc1ccc(NCc2nc(C)cs2)c(OCC(=O)N(C)C)c1 +CC(=O)Nc1cc(NCc2cccc(-c3ccncc3)c2)ccc1F +CCOc1ccccc1OCC(=O)NCc1ccccc1C +Cc1c2c(nc3cc(C(N)=O)n(C)c13)CC(C)(C)CC2=O +Cc1ccc(CNC(=O)CCCNC(=O)c2ccc(F)cc2F)cc1 +NC(=O)CSc1nnc2n(-c3ccccc3)c3ccccc3n12 +COCc1ccc(C(=O)Nc2ccccc2C)cc1 +Cc1cc(S(=O)(=O)N(C)c2c(F)cccc2C(N)=O)sc1C +N#Cc1ccnc(SCC(=O)c2ccc3c(c2)CCC(=O)N3)c1 +CC1(C)OC2(C)C(C)(O)C(C)(O)C(C)(O)C(C)(O)C2(C)O1 +Cc1ccc(-c2nnc(NC(=O)c3cc(C)on3)o2)c(C)c1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)CNC(=O)C(C)(C)C +Cc1ccc2c(c1)OCC(=O)N2CC(=O)Nc1ccccc1C +NS(=O)(=O)c1cc(Br)c2c(c1)S(=O)(=O)NCN2 +Cc1csc(NC(=O)NCCc2ccc(-n3cccn3)cc2)n1 +Cc1cc(NC(=O)c2ccccc2C(=O)Nc2cc(C)on2)no1 +COc1ccc(O)c(C(=O)Nc2ccccc2O)c1 +CN(CC(=O)Nc1cccc2c1CCCC2)S(C)(=O)=O +N#CCc1c(-c2ccccn2)nc2scc(-c3cccs3)n12 +CCn1nc(C)c(Cl)c1C(=O)NC(C)c1ccccc1 +CC(C)(C)c1ccc2c(c1)CNCC2C(=O)NCCCO +CCC(C)NC(=O)CCc1ccc(OC(C)C)c(N)c1 +O=C(NCCC1=CCOCC1)c1ccc(-n2ccnn2)cc1 +Cc1ccc(S(=O)(=O)N2CC(OCc3ccccc3)C2)c(C)c1 +Cc1nc(-c2ccccc2)ccc1C(=O)OC(C)C(N)=O +Cc1nc(C)c(CNCC2(c3ccc(F)cc3)CCOCC2)s1 +C#CC(C)(C)NS(=O)(=O)c1ccc(Cl)cc1 +CC(C)NC(=O)CCNC(=O)Nc1ccnn1C(C)C +O=S(CCSc1nccn1-c1ccccc1)c1ccccc1 +Cn1c(N)c(C(=O)CSc2ccccn2)c(=O)n(C)c1=O +Cc1cc(C)n(CC(=O)Nc2ccc(F)cc2)c(=O)c1C(N)=O +O=S1(=O)c2ccccc2C2c3ccccc3C=CC21 +N#Cc1ncc(Br)c2c(Br)ccc(N)c12 +Cc1nc(-c2ccccc2)ncc1C(=O)NCC(O)c1ccc(O)cc1 +O=C(NCCc1ccsc1)Nc1cccs1 +CNS(=O)(=O)c1cc(C(=O)NC2c3ccccc3CC2O)co1 +CC(C(=O)N(C)CC(=O)Nc1cnc2ccccc2c1)n1cccn1 +CC1(C)Oc2cc(NC(=O)C3CCCO3)ccc2NC1=O +COC(=O)CCCNC(=O)CC1NC(=O)c2ccccc2N=C1O +CCCNC(=O)NCCc1cc(F)cc2c1OCOC2 +Cc1c(C(C)NC(=O)CC(C)CCc2ccccc2)cnn1C +Cc1ccc(-c2ncco2)cc1NC(=O)NCc1n[nH]c(=O)[nH]1 +CCCOC(=O)CC1CCN(C(=O)OC(C)(C)C)CC1 +Cc1cccc(NC(=O)c2ccc3c(c2)CC(C)N3S(C)(=O)=O)n1 +Nc1cccc(OCCCc2ccc3c(c2)OCCO3)c1 +Nc1nc(N2CCCC3(CCOC3)C2)c2nc[nH]c2n1 +CC(C)NC(=O)c1cc(-c2ccccn2)nc2cc(F)ccc12 +N#CCn1cc(S(=O)(=O)N2CCCC2)ccc1=O +COC(=O)Cc1csc(NC(=O)NCc2ccccc2Cl)n1 +Cc1ocnc1CNS(=O)(=O)c1cc(Cl)ccc1Cl +CCC(C)(C)NC(=O)CSc1nccn1-c1ccc(OC)cc1 +COC(=O)CCN(C)C(=O)c1ccc(S(C)=O)cc1 +CCn1nc(-c2cc(C)ccc2F)cc(C#N)c1=O +O=C(NC1CCN(C(=O)c2ccoc2)CC1)C1CCCO1 +NC(=O)c1cc(Cc2ccccc2)sc1NC(=O)c1cccnc1 +Nc1ccccc1NC(=O)c1c[nH]c2ccccc12 +CCOC(=O)Nc1nc2c(s1)CN(C(=O)c1cccc(C)c1)CC2 +COc1ccc(Nc2nc(C)ccc2N)cc1Cl +CC(=O)c1nn(-c2ccc(F)c(F)c2F)c(C)cc1=O +O=C(c1cnccn1)N1CCN2CC(OCc3cccnc3)CC2C1 +Cc1ccccc1NC(=O)c1ccc2c(c1)NC(=O)CCS2 +Cc1nc2ccc(NC(=O)c3cccc(C)c3O)cc2o1 +CC(=O)Nc1ccc(NC(=O)NC(C)c2cc(C)sc2C)cc1 +Cc1ccccc1C(O)CN1CCN(C(C)C(=O)N2CCCC2)CC1 +Cc1ccc(F)cc1NC(=O)CCNC(=O)OC(C)(C)C +CN(Cc1nc2ccccc2n1C(F)F)C(=O)c1ccsc1 +O=C(Cc1csc(N2CCCC2=O)n1)Nc1ccc(F)cc1 +CCC1Nc2cc(OC)ccc2N(C(C)C(N)=O)C1=O +CN(C)c1cncc(N2CC3CCC(C2)N(CC2CC2)C3=O)n1 +Cc1nc2scc(-c3cccs3)c2c(=O)n1CC#N +COc1ccccc1NS(=O)(=O)c1ccc2c(c1)CC(C)N2 +Cc1ccc2c(c1)C(O)(CC(=O)c1ccccn1)C(=O)N2 +COC(=O)CNC(=O)CCCc1cc(F)ccc1F +O=C(Nc1ccnn1CCc1ccccc1)c1scnc1C1CC1 +Fc1ccc(C2=Nc3nnnn3C(c3ccccc3)C2)cc1 +Cc1cccc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)c1C +CCN(CC(C)C#N)C(=O)c1nn(-c2ccccc2)cc1OC +Cc1cc(C(C)NC(=O)NCC2CCCC2)c(C)o1 +CCCNc1nc(N2CCCCC2)nc2c1cnn2C +CCOC(=O)C(C)(C)n1nnc(S(=O)(=O)CC)c1N +CCc1c(C(=O)Cn2c(=O)sc3ccccc32)[nH]c(C)c1C(C)=O +Cc1nc(NC(=O)c2cc(Cl)c3c(c2)OCO3)n[nH]1 +CC(OC(=O)c1cc2c([nH]c1=O)CCCC2=O)C1CCCCC1 +N#Cc1cccc(NC(=O)CCn2nnc(-c3ccccc3)n2)c1 +CCn1c(=O)n(CC(=O)OCc2ccoc2C)c2ccccc21 +CCCC1CCCN(C(=O)c2ccc(S(=O)(=O)NC)o2)CC1 +CCCc1[nH]nc(C(=O)Nc2cccc(Cl)c2)c1N +COCC(C)NC(=O)C1CC(=O)N(c2ccccc2OC)C1 +CCC(CC1CCCC1)C(=O)N1CCN(CC(=O)NC(C)C)CC1 +CCOC(=O)C1CCCN(S(=O)(=O)c2cn(C)c(C)n2)C1 +CCCCNC(=O)C1CCN(c2ncnc3sc(C)c(C)c23)CC1 +COC(=O)C1Cc2ccccc2N1C(=O)c1ccc(N(C)C)nc1 +Cc1nc(CC(=O)N(C)Cc2c(F)cccc2Cl)cs1 +CCN(CC(C)C(=O)OC)C(=O)Cc1cccc(F)c1F +O=C1Nc2ccccc2C1Cc1ccc2cc[nH]c2c1 +COc1cc(N)c(Cl)cc1-c1nnc2cnccn12 +O=C(NCc1cccnc1)C1CCN(c2ccccc2)C1=O +COC(=O)C1CCn2nc(-c3ccc(OC)cc3)nc2C1 +Cc1cccc(-n2c(SC(C)C(N)=O)nc3ccccc3c2=O)n1 +Cc1ccc(CN(C)C(=O)c2ccc(OCc3ccccc3)cc2)o1 +CC(C)(C)C(=O)NCc1ccc(-n2cccn2)nc1 +COc1c(C)cc(CNCCc2c(C)nn(C)c2C)cc1C +O=C(NCCCOc1ccc2c(c1)OCO2)c1n[nH]c2ncccc12 +CC(NC(=O)c1c(Cl)c(C(F)(F)F)nn1C)C1CCCO1 +Cc1ccc(NC(=O)C2CN(S(=O)(=O)C3CC3)C2)cc1Cl +Cc1nc(C2(NC(=O)CN3CCCCCC3=O)CCCCC2)no1 +COc1ccc(-c2ncccc2F)c(OC)c1OC +CCCC1(CNC(=O)NCC2CC(=O)Nc3ccccc32)CC1 +Cn1cc(-c2nn(Cc3ccccc3C#N)c3c2CNCC3)nn1 +CC(c1ccc(Cl)cc1)N(C)C(=O)c1cn[nH]c1 +CCOC(=O)C1CCN(c2cccc(F)n2)CC1 +Cc1nnc2ccc(C(=O)NCCOc3ccc4ccccc4c3)cn12 +CCS(=O)(=O)N1CCC2C1CCC(=O)N2Cc1ccncc1 +CCn1ncc(Br)c1C(=O)NC1CCCC1 +COc1ccccc1NC(=O)CCCn1cccc1 +NC(=O)c1ccc(CSc2ncnc3ccccc23)cc1 +Cc1cc(O)cc(C(=O)N(C)CCN(C)C(=O)OC(C)(C)C)c1 +Cc1ccc(NS(=O)(=O)c2ccc(F)c(F)c2F)cc1 +Cc1ccc(Cn2cc(-c3noc(-c4cccnc4)n3)nn2)cc1 +CCCCn1cnc2c1c(=O)n(C)c(=O)n2CCCC +CC(=O)N1CCC(NC(=O)CNc2ccc(Cl)cc2F)CC1 +O=C(NCc1cccnc1OC1CCCC1)c1ccccc1 +COC(=O)c1c(C)[nH]c(C(=O)NC(C2CC2)C2CC2)c1C +C=CCOc1ccc(C(=O)NCc2c[nH]nc2C)cc1 +Cc1ccc(N(CCC#N)C(=O)COCC2CCCO2)cc1 +N#Cc1ccc(OC(=O)COc2ccccc2C#N)cc1 +O=C(NCCc1cc(F)ccc1F)N1CCCC(CO)C1 +CC(C)C1OCC2(CO)COC3(CCCCC3)N12 +O=C1c2cc(Br)ccc2OCCC1(CO)CO +C#CCOc1ccc(F)cc1NC(=O)c1scnc1C1CC1 +COc1ccnc(N2CCN(C(=O)CCc3ccsc3)CC2)n1 +COCc1nc(NC(C)(C)CC(C)(C)C)c(N)c(OC)n1 +CC1CCC(N(C(=O)c2ccc(C#N)cc2)C2CC2)CC1 +O=C(c1cccc(NCc2cscn2)c1)N1CCCC1 +CCCNC(=O)Nc1cc(-n2cnnn2)ccc1C +O=C1CCN(c2ccc(Br)cc2F)CC1 +CC1CCC(CO)(Nc2ccc(Cl)cn2)CC1 +CCc1onc(C)c1NC(=O)N(C)CCC(=O)OC(C)(C)C +Cc1ccc(-n2ccc3c(cnc4nc(C)nn43)c2=O)c(C)c1 +CC(=O)NC(CO)C(=O)N1CCc2c(ncnc2N2CCOCC2)C1 +COCCCNC(=O)c1ccc(NC(=O)c2ccncc2)cc1 +Cc1noc(C)c1C(C)NC(=O)c1ccc2c(c1)C(=O)c1ccccc1-2 +O=c1c(C(F)(F)F)cc(C2CC2)nn1Cc1nnc(C2CC2)o1 +O=C(NCCCc1nc2c(s1)CCCC2)N1CCOCC1C1CC1 +CCN(Cc1ccc(OC)cc1)C(=O)NCc1cccnc1 +Cc1ccccc1C(CC(=O)N1CCC1)NC(N)=O +c1ccc(CNc2ncnc3sc4c(c23)CCC4)cc1 +Cc1sc(CNC(=O)C2CCCO2)nc1-c1ccc(Cl)cc1 +Cc1ccccc1-n1cc(CN(C)c2nnc(C3CCC3)o2)cn1 +COc1cccc2c1C(c1cncc(F)c1)NCC2 +CC(C)(C)c1ccc(CNC(=O)Cn2c(=O)cnc3ccccc32)cc1 +O=S(=O)(c1ccc(F)cc1)N1CCc2cc(F)ccc2C1 +CCNC(=O)Nc1cccc(NC(=O)c2cc(C3CC3)[nH]n2)c1 +CC1CC(C)CN(C(=O)NCCCOCc2ccco2)C1 +O=C(Cn1cnnn1)NC1(c2ccc(Cl)cc2)CC1 +NC(=O)CCSc1nnc2ccc(C(F)(F)F)cn12 +CCC(NC(=O)N(C1CC1)C(C)c1ccco1)c1nccs1 +CC(C)C(Sc1nnnn1C(C)C)C(=O)NC1CCCCC1 +CCn1c(SCC(=O)N(C(C)C)C(C)C)nc2ccccc2c1=O +Cc1ccc(-n2ccnc2)c(C(=O)N2CCc3cc(F)ccc3C2)c1 +N#CCOc1cccc(CC(=O)Nc2ccn(-c3ccccc3)n2)c1 +Cc1ccc(-n2nc(C(F)(F)F)cc2N)c(C)c1 +CC(=O)OC1N=C(c2ccccc2)c2cc(Cl)ccc2NC1=O +COCCOc1ccc(NC(=O)c2cc(F)c(F)c(F)c2F)cn1 +CN(CCc1ccncc1)Cc1ccccc1Br +CC1CCN(C(=O)c2cccc(NC(=O)C3CCC3)c2)CC1 +C=C(C)CN1C(=O)C(O)(CC(=O)c2ccc(F)cc2)c2ccccc21 +Fc1cccc(F)c1NCc1ccc2c(c1)OCCO2 +CCCc1nc(S(=O)(=O)c2ccccc2)c(NC)o1 +CCc1ccc(CCC(=O)Nc2ccc(-n3cncn3)cc2)cc1 +CCCNC(=O)Cn1ccc2ccc(-c3nnc(C)o3)cc21 +CNC(=O)c1oc2ccccc2c1COc1ccccc1 +CCCN1C(=O)C2CCC1CN(C(=O)c1nn(C)c3c1CCCC3)C2 +CC(NC(=O)c1ccc2c(c1)NC(=O)CS2)c1ccc(Cl)cc1 +Cc1ccc(NC(=O)C(C)N2CC(C)Oc3ccc(N)cc32)cc1 +CNC(=O)C(CC(C)C)NCc1cnn(-c2ccccc2)c1 +CCCN(C)S(=O)(=O)N1CCCC1c1ccco1 +Cc1oc(-c2ccco2)nc1CC(=O)NCCNC(=O)c1ccn[nH]1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1ccc(C#N)c(Cl)c1 +O=C(Nc1nccs1)c1c(-n2cccc2)sc2c1CCCC2 +CC(C)(C)c1cc(NC(N)=O)nc(C(C)(C)C)n1 +CC(C)c1cc(C(=O)N(C)Cc2n[nH]c3c2CCCC3)no1 +O=C(Nc1ccc(F)cc1)c1cccc(-n2cnnn2)c1 +O=C(Cc1cccs1)N1CCn2nc(-c3ccccn3)nc2C1 +CN(CC(=O)NCc1ccncc1)c1nc2ccccc2s1 +O=C(c1ccnnc1)N1CCOC2C(Oc3ccccn3)CCC21 +CCCC(=O)N(C)C1CCN(c2ccc(F)cc2)CC1 +CN(Cc1ccccn1)C(=O)Nc1ccc(F)c(C(N)=O)c1 +CCCCS(=O)(=O)Nc1ccc(NC)c(C)c1 +CCn1cc(NC(=O)C2CCC(=O)N2Cc2ccco2)cn1 +Cc1cc(C)cc(CCNC(=O)NCc2cscn2)c1 +CCn1nc(C(=O)NC(C)c2cccs2)c2ccccc2c1=O +NC(=O)c1ccccc1COC(=O)C1(c2ccccc2F)CC1 +CC(C)OCCCNC(=O)c1cc(=O)c2cccc(F)c2[nH]1 +COc1ccccc1-c1ncc(CN(C)Cc2c(C)noc2C)cn1 +Cc1cc(N2CCC(C(=O)N3CCCC3)C2=O)ccc1F +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)NCc1cccs1 +COc1ccc(S(=O)(=O)N2CCOCC2)c2ccccc12 +N#Cc1cccc(OCc2cccc(C(N)=O)c2)c1 +O=C(c1ccc(OCC(F)F)nc1)N1CCC2(CCCCC2)C1 +O=C(c1ccc(NCC2COc3ccccc3C2)nc1)N1CCCC1 +CC(C)C(=O)c1ccccc1NC(=O)C(C)c1ccsc1 +Nc1nc(SC2CCc3ccccc3N=C2O)n[nH]1 +O=C(NCc1ccccc1Br)Nc1cccs1 +Cc1cc(CNc2cccc(C(=O)N3CCOCC3)c2)no1 +COc1ccc(C(=O)N2CCC3(CCN(C(C)=O)C3)C2)cc1 +C=CCn1cc(C(=O)c2cc(F)ccc2O)cc(C#N)c1=O +O=S(=O)(c1ccc(N2CCCCC2)cc1)N1CCOCC1 +Cc1cc(NC(=O)NCc2cnn(C)c2)ccc1-n1cnnn1 +Cc1nn(C)c(C)c1CCC(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1ccc(OC(=O)C2CCCN2C(=O)C2CC2)cc1C +Cc1ccc(O)c(NC(=O)c2ccc(-n3ccnn3)cc2)c1 +Cc1cc(C(=O)N2CCN(C(=O)c3ccn(C)c(=O)c3)CC2)c(C)o1 +Cn1cc(C(=O)OCC2CCCO2)c(-c2cccs2)n1 +O=S(=O)(NCCc1cccc(F)c1)N1CCCCCC1 +Cc1cc(Oc2ncnc(-n3ccnc3)c2N)cc(C)c1Cl +CNC(=O)NCC(=O)NCCNc1ccc(C(F)(F)F)cn1 +N#CCCN(c1nccs1)S(=O)(=O)c1ccccc1 +O=C(c1ccsc1)N1CCN(C(=O)c2ccn3ccsc23)CC1 +CCCNS(=O)(=O)c1ccc2c(c1)C(=C1CCCC1)C(=O)N2C +COc1ccc(N)cc1CNS(=O)(=O)c1cccnc1 +Cc1ccc(NC(=O)C2CCN(C(=O)C3CC(=O)N(C)C3)CC2)nc1 +CC(C)n1ncc(Br)c1C(=O)NC1CC1 +CC(C)(C)n1cc(C(=O)Oc2ccc(N3CCOC3=O)cc2)cn1 +CN(CCOCC1CC1)C(=O)c1cn(-c2ccccc2Cl)nn1 +CC(=O)Nc1ccccc1S(=O)(=O)c1ccccc1 +COc1ccc(F)cc1NC(=O)CCN1C(=O)COc2ccccc21 +Cc1nc2ccccc2n1CCNC(=O)CCc1nc2ccccc2[nH]1 +O=C(Nc1nncs1)c1nc(-c2ccccc2)cs1 +O=c1[nH]cc(-c2ccc(OCc3ccccc3)cc2)c(=O)[nH]1 +CC(C#N)NS(=O)(=O)c1cccc2nonc12 +O=C(NCc1ccccc1F)NCC1CCCCO1 +CCN(CC)c1ncnc(NCCN2CCOCC2)c1N +COC(=O)CCn1c(C)nc2cc(C(F)(F)F)ccc21 +CS(=O)(=O)NCCCNC(=O)c1c[nH]c2ccccc2c1=O +Cc1ccc(CNC(=O)Cc2csc(NC(=O)C(C)(C)C)n2)cc1 +COCCN(CC(=O)N(C)C)C(=O)Cn1ccccc1=O +C#CCOC(=O)CSc1ccc(OCC)cc1 +CC(NC(=O)c1cnn(-c2ccccc2)c1)c1nc2ccccc2[nH]1 +COc1ccc(C(C)CC(=O)N2CCC(O)C2)cc1 +CC=CCOC(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C +Cn1c(-c2ccc(F)cc2)cnc1NC(=O)c1ccccc1 +Cc1n[nH]c2c1C(c1ccc(O)cc1)c1c([nH]c(=O)[nH]c1=O)N2 +Cc1nc2nc(C(C)C)c(-c3cccc(Cl)c3)c(N)n2n1 +CCC(C(=O)NC(C)c1nc(-c2ccncc2)n[nH]1)c1ccccc1 +CC(=O)Nc1cc(C(=O)N(Cc2ccccc2F)C2CC2)ccc1C +O=C(c1ccco1)N1CCC(c2nnc(-c3ccc(F)cc3)o2)CC1 +Cn1nc(C(=O)NC2CCCCCC2)cc1NC(=O)c1ccco1 +CC(C)CN1C(=O)C(c2ccccc2)Oc2cccc(N)c21 +COc1cc(F)c(NC(=O)CCCc2ccccn2)cc1OC +N#Cc1ccc(N2CCCN(c3nccs3)CC2)c(F)c1 +O=S(=O)(c1cc(F)ccc1Cl)N1CCOCC1C1CC1 +CS(=O)(=O)c1cccc(C(=O)NCC2CC3CCC2C3)c1 +O=C(Cn1cnc2ccccc2c1=O)NCC(=O)NC1CC1 +CCn1cnnc1CNC(=O)c1nc(N2CCCCC2)ncc1Cl +CNc1nc(CN(C)C(C)CC#N)nc2sccc12 +CC(=O)N1CCOCC2(CCN(C(=O)C3(C#N)CC3)CC2)C1 +COCc1c(CO)nnn1-c1ccc(Oc2ccccc2)cc1 +CCc1ccc(CN(C(=O)C2CCC2)C2CC2)cc1 +CCc1onc(C)c1NC(=O)N(C)CCOc1ccc(OC)cc1 +Cc1cc(C)cc(-n2nnnc2SC2CCOC2=O)c1 +COc1ccc2c(c1)CC(C(=O)Nc1ccc3c(c1)OCO3)CO2 +CC(C)(C)C(=O)CN(c1nccs1)S(=O)(=O)c1ccccc1 +COc1cccc(C(O)CNC(=O)c2cccc(Cl)c2)c1 +Cc1cc2ccccc2n2c(=O)n(CC(=O)NC3CCCC3)nc12 +O=C1CCN(C(=O)c2ccnc(OC3CCC3)c2)CCN1 +C#CC(OC(=O)c1ccc(-n2nc(C)cc2C)cc1)C1CC1 +C#CCNC(=O)c1cnn(-c2ccccc2F)c1-n1cccc1 +Cc1ccccc1-n1ncc(C(=O)NC(C)CO)c1C(F)(F)F +Cc1nn2c(NCC(O)CO)cc(-c3ccccc3)nc2c1C +Cn1nc2n(c1=O)CCN(S(=O)(=O)C1=Cc3ccccc3CC1)C2 +COC(=O)C(Cc1c[nH]c2cc(Cl)ccc12)NC(C)=O +NC(=O)NCc1ccc(C(=O)OCCc2ccccc2)cc1 +Cc1cc(C)n(-c2ccc(F)cc2F)c(=O)c1C#N +N#CCOc1cccc(CNC(=O)c2c[nH]c3cccc(F)c23)c1 +COC(=O)N1CCC(NC(=O)NC(C)c2cc3ccccc3o2)CC1 +CCn1nc(C)c(S(=O)(=O)NCCCN2CCOCC2)c1C +O=c1[nH]cnc2c1c(-c1ccccc1)cn2-c1ccc(F)cc1 +COc1ccccc1CNCCc1cccc(F)c1 +COc1cccc(C2NCCc3ccc4c(c32)OCO4)n1 +OC1(Cn2cnc3cc(F)c(F)cc32)CCCCC1 +CC1CN(C(=O)Cc2cc3ccccc3[nH]c2=O)c2ccccc21 +COCc1nc2n(n1)C(c1ccc(C(C)C)cc1)CC(C)N2 +Cc1noc(-c2cccnc2N2CCN(C(=O)C3CC3C)CC2)n1 +CCn1c(=O)n(CC(=O)NCc2ccc(C)cc2)c2ccccc21 +C#CCOC(=O)C(NS(=O)(=O)c1ccccc1F)C(C)C +Cc1cc(NC(=O)c2sc(NC(=O)c3ccco3)cc2C)[nH]n1 +CC(C)(C)c1nc(CNc2ccccc2CO)cs1 +COCCCN(C)C(=O)Nc1ccc(C)cc1Cl +CN(C)C(=O)CNC(=O)c1n[nH]c2ccc(N)cc12 +CC(C)CCCC(C)NC(=O)N1CCN(C(=O)N(C)C)CC1 +CC(=O)N1CCC(CNS(=O)(=O)c2cc(F)c(C)cc2F)CC1 +Cc1ccc(C(C)(C)C(=O)N2CC(C(=O)N3CCN(C)CC3)C2)cc1 +COc1ccc(SCCC(=O)Nc2nccs2)cc1OC +Cc1nnc(CNC(=O)CN(C)c2nc3c(C)ccc(C)c3s2)o1 +CCCc1cc(C(=O)NCCN2CCOCC2)cs1 +CC(C)c1nnc2n1CC(NC(=O)c1ccc3c(c1)OCO3)CC2 +Cc1ccc(SCCC(=O)N2CC(C)OC(C)C2)cc1 +O=C(Cc1ccon1)N1CCOc2ccc(F)cc21 +N#Cc1cccc(CC(C#N)c2cccc(C#N)c2)c1 +CCOc1c(O)c(Cl)cc2c1C(C(C)(C)O)NCC2 +O=C(CCSc1ccccn1)OCC(=O)N1CCCC1 +O=S(=O)(Cc1ncc(-c2ccccc2)o1)c1ccc(F)cc1 +Cc1ccc(CCC(=O)NCC2(C(N)=O)CCOCC2)cc1 +CCOCc1nnc2n1CCN(c1ccc(C)nn1)CC2 +COC(=O)C1CC(O)CN1Cc1ccc(C)c(F)c1 +CCc1cc(N2CCN(C(=O)C3CCCN(C(C)=O)C3)CC2)ncn1 +CCOCC(=O)Nc1ccc(OC)c(Br)c1 +COC(=O)CCC(O)c1cc(C)c(OC)cc1C +COc1cc(N)c(OC)c(S(=O)(=O)NC(C)C)c1 +CCN(CC(C)C#N)C(=O)c1cc(C)n(Cc2ccccn2)c1C +CCc1ccc(C(=O)N(CC(=O)OC)C2CCCC2)o1 +Cc1ccc(OC(C)C(=O)N2CCN(c3ccc(O)cc3)CC2)cc1 +CCOC(=O)c1noc(C(=O)NCC(C)C)c1N +CCCOC1CCCN(C(=O)c2ccc3oc(C(C)C)nc3c2)C1 +COc1ccc(NC(=O)c2cn(C)c3ccccc3c2=O)cc1 +COc1ccccc1CC(C)(C)NC(=O)c1ccoc1 +CCc1ccc(CN2CCc3nnc(CNC(C)=O)n3CC2)o1 +COc1ccc2[nH]cc(C(=O)NCCc3ccc(F)cc3)c2n1 +Cc1cc(C)c(CNC(=O)N2CCCC2c2cc(C)on2)c(=O)[nH]1 +CCCOc1cc(C)ccc1NC(=O)N1CCCC(CNC(C)=O)C1 +CC(=O)NC1(C(F)(F)F)Oc2cc(Cl)c(Cl)cc2O1 +O=C(CN1CCCSc2ccccc21)N1CCCCC1 +Cc1occc1COC(=O)c1cnc2c(cnn2CC(C)C)c1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NC(C)CO +COC(=O)c1ccc2c(c1)CCN2C(=O)Cc1c(C)noc1C 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+COc1cc(C)nc(N2CCN(C(=O)CCc3ccncc3)CC2)n1 +COc1ccccc1OCCCc1cncc(C(N)=O)c1 +Cn1c(NC(=O)Cc2cccc3ccccc23)cc(=O)n(C)c1=O +CCSc1ccccc1C(=O)Nc1cc(C)nn1CC +Cc1ccc(OCC(=O)NC(C#N)c2cccc(C)c2)cc1 +Cc1csc(C(=O)NCC#CCOc2ccc(C)nc2)c1 +Cc1nc(-c2ccccc2)sc1CNC(=O)NCC(C)(C)C(N)=O +Cc1c(-n2cnnc2)cc(C(N)=O)cc1-n1cnnc1 +CCCCCNC(=O)Cc1noc2c(N)cc(C)cc12 +CCOC(=O)c1cccc(NC(=O)c2cccnc2OCC)c1 +CCOC(=O)c1ccc(CN2CCCC(c3nncn3CC)C2)o1 +Cc1c(C(C)NC(=O)Nc2ccccc2N2CCCCC2)cnn1C +Cc1csc(NC(=O)CCC(=O)c2ccc(F)c(F)c2)n1 +CC(C)(C)c1ccc2c(c1)-c1n[nH]c(C(N)=O)c1CCO2 +COc1c(OC(C)C)ccc2c1C(c1ccc[nH]1)NCC2 +CCc1noc(CC)c1CNC(=O)c1ccc(C(=O)OC)cn1 +Cc1cc(C)n(C(C)C(=O)NC(c2ccc(F)cc2)C2CCCO2)n1 +Nc1nc(C(=O)c2ccc(Cl)cc2Cl)no1 +COC(=O)c1ccc(CN(C)Cc2cnc3cc(C)ccn23)cc1 +Cc1ccc2c(CC(=O)C(C#N)c3ccccn3)coc2c1 +O=c1c2ccncc2ncn1Cc1cccc(-n2cccn2)c1 +COc1ccc(C(=O)N(C)CCOc2ccc(Cl)cc2)cc1OC +CN(C(=O)CSc1ccc(-c2cccnc2)nn1)c1ccccc1 +CCN(C(=O)c1cc(N)cc(OC)c1OC)c1ccccc1 +CCCCNC(=O)C(C#N)c1nc2ccccc2nc1OC(C)C +O=C1CCCc2[nH]c(=O)c(C(=O)N3CCC4(CC3)OCCO4)cc21 +COc1cc(N)c(Cl)cc1C(=O)OCC(=O)N(C)c1ccccc1 +CCCc1ccc(S(=O)(=O)N(C)CC(=O)NCC)cc1 +CSc1ccccc1N(C)C(=O)c1cccnc1OCC(F)F +O=C(CCn1c(-c2ccccn2)cc2cccnc21)NC1CCCC1 +O=C(Nc1ccccc1Cl)c1cnc2ccccc2n1 +CCCCNc1nc(-c2scnc2COC)cs1 +CC(C)Oc1ccccc1NC(=O)Cc1cn2ccsc2n1 +CN(Cc1ccc(O)cc1)C(=O)c1ccc2c(c1)CCN2 +CSc1ccsc1C(=O)N(C(C)C)C1CCOCC1 +CC(C)(C)Nc1nc(SCC(N)=O)nc(N2CCOCC2)n1 +CC(=O)c1csc(NC(=O)C2CC(=O)N(CC(F)(F)F)C2)n1 +CCC(CC)c1nnc(NC(=O)N(C)CCOC)s1 +Cc1ncsc1-c1nnc(CNC(=O)c2ccccc2F)o1 +COCCNC(=O)c1ccc(OC)c(Br)c1 +CC(=O)N(C)c1ccc(NC(=O)CNc2c(C)cc(C)cc2C)cc1 +Cc1cnc(CNC2(c3nccs3)CCCC2)cn1 +CCn1cc(Cl)c(C(=O)Nc2cc(C(F)(F)F)ccc2F)n1 +COc1ccc(CCNC(=O)c2ccn3nccc3c2)cc1 +C=CCCCN(C)S(=O)(=O)Cc1cccc(C#N)c1 +COC(=O)C1CCN(S(=O)(=O)c2ccc(C(C)C)cc2)CC1 +COC(=O)c1ccc(CSc2ccc(-n3nc(C)cc3C)nn2)o1 +Cc1ccc(C)c(-n2ccnc2SCC(=O)OCC(N)=O)c1 +CCn1cnc2ccc(C(=O)N3CCOCC3)cc2c1=O +Cc1cccc(CC(=O)N2CCOCC2c2c(C)n[nH]c2C)c1 +O=C(Nc1cccc(N2CCOC2=O)c1)C1CCCO1 +Cc1cc(NC(=O)C2(c3cc(-c4cccs4)on3)CC2)no1 +CS(=O)(=O)c1nc2ccccc2n1CCn1cc(C#N)cn1 +O=C1C=C(c2ccc(Cl)cc2)Nc2cccnc2N1 +COC(=O)c1ccc(-c2cccs2)n2nc(C(F)(F)F)nc12 +CC(C)Oc1ncnc(-n2cnc3ccccc32)c1N +N#Cc1ccc(NC(=O)N2CCC(O)CC2)cc1Cl +CC(=O)c1ccc(S(=O)(=O)Cc2ccccc2Cl)cc1 +COCC12CCCOC1CCN(C(=O)c1ccc3ncccc3c1)C2 +COC1CCC(N(C)C(=O)COc2c(C)cccc2C)CC1 +CC(=O)N1c2ccccc2CC1C(=O)Nc1ccc2ccccc2n1 +Cc1ccc(NC(=O)N2CCC(c3nnc4ccccn34)CC2)c(C)c1 +CC(O)CNC(=O)CCSc1ccc(F)c(F)c1 +O=C(Nc1ccccc1N1CCCC1)c1nc2ncccn2n1 +CC(NC(=O)Nc1nc(-c2ccccc2)ns1)C1CC1 +Cc1csc(S(=O)(=O)C(C)C(=O)Nc2ccc(C)c(C)c2)n1 +Cc1nc(COCC2OCCc3cn(C)nc32)cs1 +Cc1ccc(Nc2nc(N)c(C#N)c(CC#N)c2C#N)c(C)c1 +COC(=O)c1ccc(-c2ccc(Br)cc2)[nH]c1=O +NC(=O)c1ccc(NC(=O)c2cccc(-c3ccoc3)c2)c(F)c1 +COc1ccc(CNC(=O)c2ccc(-n3cccn3)cc2)cn1 +CCOC(=O)C1(NC(=O)c2cc(C)nn2C)CCCC1 +CCCN(CCO)C(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1 +CCCCCNS(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +CC(=O)NCC(=O)NCc1cc(Cl)c2c(c1)OCCO2 +CC(C)(O)CN1CCN(C(=O)COCC(F)(F)F)CC1 +Cc1nnsc1C(=O)NCC#Cc1cccc(Cl)c1 +COc1ccc(NC(=O)c2cccn2-c2cccnc2)c(OC)c1 +CC(O)c1ccc(Oc2cccc(N(C)C)c2)cc1 +CCN(CCNS(=O)(=O)N(C)C)c1ccccc1C +O=C(Nc1nc(-c2ccco2)cs1)c1cc(-c2cccnc2)on1 +NC(=O)c1cccc(NC(=O)c2cc(Cl)c3c(c2)OCO3)c1 +O=C(COCC(F)(F)F)NC1CCSc2ccc(Cl)cc21 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)Nc1cnn(C)c1 +CCOC(=O)N(C)c1ccc(NC(=O)c2ccc(C)s2)cc1 +NC(=O)CCN1CCN(C(=O)c2c(F)cccc2Cl)CC1 +COc1ccc(C(=O)N(Cc2ccc(C)o2)C(C)C)c(OC)c1 +CC(C(=O)NCc1csc(C(C)(C)C)n1)n1ccnc1 +Cc1ccc(OCCOC(=O)c2cc(=O)[nH]c3ccccc23)cc1 +COc1ccccc1Oc1ccc(CNC(=O)Cc2ccc[nH]2)cc1 +CCCNC(=O)c1ccc(NCc2noc(CC)n2)cc1Cl +NC(=O)c1ccccc1OCC(=O)Nc1ccc(OC(F)F)cc1 +Cc1cc(Cl)ccc1OCC(=O)N(CCC#N)CCC#N +Cn1c(SCC(O)CN2CCOCC2)nnc1-c1ccccc1 +CN(CCOc1ccc(F)cc1)C(=O)c1ccc(-n2ccnn2)cc1 +CC(C)(C)C(=O)NCCCC(=O)NCC(=O)N1CCCC1 +COc1cccc(CCN(C)C(=O)CCCO)c1 +Cc1nc(C2CCCN(C(=O)C3CC3c3cccc(F)c3)C2)no1 +O=C(NCC1CCCO1)c1ccn2c(-c3ccc(F)cc3)nnc2c1 +CCC(CC)c1nnc(NC(=O)c2csc(C)n2)s1 +COC(=O)C1CCC(NC(=O)c2ccc(OCC(F)F)nc2)CC1 +COc1ccc(-c2c(-c3ccccc3)noc2N)cc1 +CCOCC(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 +CCCCCCNC(=O)Nc1ccc(C)c(C(N)=O)c1 +O=C(CSc1ncn[nH]1)c1cccc2ccccc12 +O=C(Nc1ccc(C(F)(F)F)cc1)C(O)c1ccc(F)cc1 +Cc1ccc2c(CC(=O)N3CCCCC3)coc2c1 +Cc1nn(C)c(C)c1C(C)NC(=O)NC(c1nccs1)C1CC1 +Cc1ccc(CC(=O)NC(C#N)CC(C)C)s1 +O=C1CCc2cc(C(=O)Nc3nnc(C4CC4)s3)ccc2N1 +O=C(NCc1n[nH]c2c1CCC2)c1cn(CC2CCCCC2)nn1 +Cc1ccc(C(O)CNS(=O)(=O)c2ccc(Cl)cc2)o1 +Cc1ccc2c(c1)N(CC(=O)N1CCC3(CC1)OCCO3)C(=O)CO2 +Cc1n[nH]cc1CNCCc1ccc(C(F)(F)F)cc1 +C#CCC(Nc1ncc(Br)cn1)C(N)=O +CCNC(=O)c1cccc(NC(=O)C(C)OCC)c1 +CC(NC(=O)C1CCCN1C(=O)c1cccs1)c1ccc(F)cc1 +COc1cc(S(=O)(=O)N2CCN(C)CC2)ccc1Cl +Cn1cc(C(=O)N2CCN(c3ncc(Cl)cc3Cl)CC2)cn1 +Cc1ccc(NC(=O)c2cn(C)nc2C)cc1S(C)(=O)=O +O=C(CCn1cnc2cnccc2c1=O)Nc1cc(F)cc(F)c1 +CCCCN(C)C(=O)c1cc2cccnc2n(Cc2ccccc2)c1=O +Cn1c(=O)c2c(-c3ccc(F)cc3)n(CC(N)=O)cc2n(C)c1=O +Cc1ccc(CN2CC(C(=O)Nc3nc4ccccc4[nH]3)CC2=O)cc1 +CC(C)(C)OC(=O)NCCNC(=O)C1CC2CCC1C2 +CCN(Cc1c(C)n(C)n(-c2ccccc2)c1=O)C1COCC1O +Cn1nc(-c2cccs2)c(-c2ccccc2)c1N +CC(Cc1cccs1)Nc1nc2nonc2nc1N1CCOCC1 +CCOC(=O)C(C)Nc1ccc2oc(C3CC3)nc2c1 +COC(=O)CCNc1ccc(S(C)(=O)=O)cc1 +O=C(NCc1ccco1)c1cc(-c2ccccc2O)no1 +CCN(C(=O)c1ccc2[nH]cnc2n1)C(C)Cc1ccc(OC)cc1 +COC(=O)Nc1cccc(NCC(=O)NC2CCCCC2C)c1 +Cc1cnn(CCC(=O)Nc2ccc(-n3ccnc3)cc2)c1 +CC(Oc1ccccc1)C(=O)OCC1CCCO1 +CCC(C)C(=O)N1CCN(C(=O)c2cccs2)CC1 +CN(CCc1c(F)cccc1Cl)S(=O)(=O)CCCO +CC(=O)C1C(c2ccccc2)c2c(n[nH]c2C)CC1(C)O +c1ccc(-c2noc(-c3cc4ccccc4[nH]3)n2)nc1 +O=C(c1cccc(F)c1)N1CCC(c2n[nH]c3ncccc23)CC1 +N#CC(CC(=O)Nc1cccc(F)c1)c1ccco1 +Cc1ccc(CN(C)S(=O)(=O)c2ccc(C#N)cc2)c(C)c1 +CC(=O)c1ccc(OC(=O)c2cnn(-c3ccccc3)c2)cc1 +O=C1CC(C(=O)NCc2nnc3n2CCCCC3)c2ccccc2N1 +CC(C)(C)CCNc1cc(S(N)(=O)=O)ccc1Cl +COc1ncccc1CNS(=O)(=O)c1ccc(C(C)(C)C)cc1 +CC(C)C(NC(=O)C1CCOCC1)c1ccccc1 +N#Cc1ccccc1OCC(=O)NCc1ccoc1 +Cc1n[nH]c(C)c1C1COCCN1C(=O)c1cc(Cl)c[nH]1 +CC(C)(C)OC(=O)N1CCc2cc(C#N)ccc2C1 +CC(=O)NCCNS(=O)(=O)c1cc(Cl)ccc1C +Cc1ccc(CNCc2cccnc2-n2ccnc2)o1 +Cc1cc(C)n(CC(=O)Nc2ccc(C(C)C)cc2)c(=O)c1C(N)=O +CC(C)(C)C(=O)NCC(O)c1ccc2c(c1)OCO2 +CC(C)N(CCC(N)=O)C(=O)c1ccc(C(F)(F)F)cc1 +COC(=O)c1cccc(C(=O)NC2C3CCOC3C2(C)C)c1 +CCC1CN(C(=O)c2cnc(SC)n2-c2ccc(F)cc2)CCO1 +O=C(NC(c1ccc(F)cc1)c1ccccn1)C(O)c1ccccc1 +O=C(Nc1ccc2[nH]ccc2c1)c1ccc(OCC(F)F)nc1 +COc1ccc(NC(=O)COc2ccc(CC(N)=O)cc2)c(Cl)c1 +CCSc1nnc(NC(=O)c2cn(C)nc2C)s1 +Cn1cnc(CNS(=O)(=O)Cc2ccccc2Cl)n1 +O=C(NCC1CN2CCCC2CO1)N1CC2CCCC2C1 +CCn1c(SCCCNC(C)=O)nc2ccsc2c1=O +CC1CCCCN1C(=O)Cn1c(C2CCCO2)nc2ccccc21 +COC1CCCOC12CCN(C(=O)c1cnn3ccccc13)CC2 +COc1cccc(-c2nc(-c3nonc3N)no2)c1 +CCn1c(CN(C)S(=O)(=O)CC)nc2ccccc21 +O=S1(=O)CCCN1Cc1nnc(-c2ccccc2)o1 +Nc1ccc(Nc2cccc3cccnc23)c(F)c1 +COc1ccc(N(C)C(=O)COc2ccc(C#N)cc2)cn1 +COCc1ccccc1NC(=O)c1sccc1N +CC(CN1CCCC1=O)NC(=O)c1cccc(Br)c1 +Cn1cc(NC(=O)C2CCCN(S(C)(=O)=O)C2)cn1 +O=C(Cn1c(=O)sc2ccccc21)NCc1cccnc1 +CC(C)n1c(SCc2nc(N)nc(N(C)C)n2)nnc1N(C)C +CCc1cc(C#N)c(NC(=O)c2ccc(C(F)(F)F)nc2)s1 +Cc1cnc(CNS(=O)(=O)Cc2cc(Cl)ccc2F)o1 +CCOC(=O)C(C)Sc1nc(-c2ccccn2)n[nH]1 +CC(C)NC(=O)c1ccc2c(c1)nnn2CCNC(=O)OC(C)(C)C +CC(=O)N1Cc2ccccc2CC1C(=O)NCCc1cccs1 +O=C(Nc1cccc(CNc2ccc3nnnn3n2)c1)c1ccncc1 +CC(c1ccncc1)N(C)C(=O)NCCC1CCCC1 +COc1ccccc1-c1noc(Cn2nc3n(c2=O)CCCCC3)n1 +COC(=O)c1ccn(CC(=O)NCc2ccc(OC)cc2)n1 +CCNC(=O)CN(CC)S(=O)(=O)c1c(Cl)cccc1Cl +O=C(Nc1ccccc1)c1cc(-c2ccncc2)[nH]n1 +CC(C)(C)c1ncc(NC(=O)N2CCN(Cc3ccon3)CC2)cn1 +Cc1ccc(C)n1-c1nc2ccc(C(=O)NC3CC3)cc2s1 +C=CCNC(=O)c1cc(S(N)(=O)=O)c(C)cc1C +COc1ccc(C(=O)CCC(=O)N2CCCC2)cc1N +COc1ccnc(NCC(c2ccccc2)N2CCOCC2)n1 +COc1ccc(F)cc1NC(=O)C1CCOc2ccccc21 +CCCCN(C)S(=O)(=O)c1cc(C(=O)CC)ccc1C +c1ccc2c(CCCc3nc(-c4ccncc4)no3)c[nH]c2c1 +CC1(C)COCCN1C(=O)CCc1cc(Cl)cs1 +COc1ccc(CNc2ncccc2CO)cc1F +CC1CCN(C(=O)NCc2ccc(Br)cc2)CC1O +COCc1ccccc1NCc1ccc(C#N)cc1F +CCOc1ccc(OCC(=O)N2CCN(c3ncccn3)CC2)cc1 +CCOC(=O)c1sc(NC(=O)c2cc(C(C)C)[nH]n2)nc1C +Cc1nc(C2CCN(C(=O)C(C)C)CC2)nc(N2CCOCC2)c1C +CCCCOc1cccc(C(=O)Nc2nc3ncccc3o2)c1 +CC(=O)c1ccc(CNC(=O)Nc2ccccn2)nc1C +CCOc1ccc(F)c(C(=O)NCc2nc3ccc(F)cc3[nH]2)c1F +N#CC(NCc1ccccn1)c1c(Cl)cccc1Cl +Cc1ccc(C(=O)Nc2ccc3c(c2)OCO3)cc1NS(C)(=O)=O +CN(CCC(F)(F)F)C(=O)c1ccccc1OCC(N)=O +CN(C)C(=O)N1CCN(C(=O)C2CCOc3ccccc32)CC1 +O=C(c1cscn1)N1CCc2ncnc(NC3CCC3)c2CC1 +Cc1cc(NC(=O)CNC(=O)COc2ccccc2)ccn1 +CCc1ccc(NC(=O)C(Cc2c[nH]c3ccccc23)NC(C)=O)cc1 +CC(Oc1ccccc1)C(=O)Nc1cc(C(=O)N(C)C)cn(C)c1=O +O=C(Nc1nccs1)c1nc(-c2cnccn2)no1 +Cc1ccc(C(O)CNc2cccc(C#N)c2)cc1 +CCc1cc(SCC(N)=O)n2c(nc3ccccc32)c1C#N +Cc1ccccc1C1CC1C(=O)NC(C)C(=O)NC(C)(C)C +CCc1nc2ccccc2n1CC(=O)NCC1(C(N)=O)CCOCC1 +Cc1n[nH]cc1NC(=O)C(OCC1CCCO1)C(C)C +COc1cccc(C2=Nc3nnnn3C(c3cccc(F)c3)C2)c1 +O=C1CC(c2cccc(Cl)c2)c2c(c3ccccc3[nH]c2=O)O1 +CC(C)(C)NC(=O)Cn1nc(C2CC2)cc(C(F)(F)F)c1=O +Oc1cc(F)c2c(c1)C(c1cnccc1Cl)NCC2 +CC(Oc1ccccc1Br)C(=O)NCCC1CCCO1 +CCn1cnnc1CNC(=O)C1(c2cc(C)cc(C)c2)CC1 +O=S(=O)(Nc1ccccc1)c1cc(F)cc(F)c1 +CC=Cc1cc(C(=O)NC2CC2)cc(OC)c1OC +Cc1ccc2c(C(=O)NCc3ccco3)nccc2c1N +O=c1c2nc(-c3ccc(F)cc3)cn2ccn1-c1ccc(F)cc1 +O=C(NC1CCN(C(=O)c2ccoc2)CC1)c1ccc(O)c(Cl)c1 +CCc1nc(CN2CCN(Cc3ccccn3)CC2)cs1 +CCOC(=O)C1CCN(C(=O)NCc2c(C)nn(CC)c2C)CC1 +COC1CCCN(C(=O)C(NC(=O)CC(C)C)c2ccccc2)C1 +Cc1cc(C(=O)N2CC(C(=O)NCCOc3ccccc3)C2)no1 +Cn1c(C(=O)N2CCC(c3n[nH]c(C4CC4)n3)CC2)cc2ccccc21 +CC1CCC(C(N)=O)CN1C(=O)c1ccc(N(C)C)c(F)c1 +O=C(Cn1cnc2cc(F)ccc2c1=O)NC1CCOCC1 +COCCOC(=O)CCc1c(C)nc2c(C#N)cnn2c1C +COC(=O)CCc1ccc(OC)c(Cl)c1Cl +COC1CCCC1NC(=O)c1cc(F)c(F)c(F)c1 +O=C(NCCc1cccs1)N1CCCC1CO +O=c1ccc(C2NCCc3cc4cc[nH]c4cc32)n[nH]1 +CNC(=O)c1cccc(NC(=O)C2CC3CCC2O3)c1C +COC(=O)C(C)(C)NC(=O)CNC(=O)C(C)(C)C +Cc1cc(C)c(C(=O)N2CCOCC2CC(=O)c2ccco2)[nH]1 +Nc1cc(Cl)ccc1-c1nnnn1CCC(F)(F)F +CC(=O)c1cccc(NCCOc2cccc(N)c2)c1 +COc1ccc(C(O)CNC2CCc3ccc(F)cc32)cc1 +O=C(Nc1ccccc1Cc1nc(-c2cccnc2)no1)c1ccco1 +CCN(C(=O)CNC(C)=O)C(C)c1cc2ccccc2o1 +CCCn1c(=O)c2c(nc3n2CCCN3c2ccccc2)n(C)c1=O +COC(=O)CC1CN(Cc2cccc3cn[nH]c23)CCO1 +O=C1C(=O)N(CC2CCCCC2)c2cc(F)ccc21 +CC(C)NC(=O)c1cn(C2CCN(C(=O)CC3CCCC3)CC2)nn1 +O=C(c1cnccn1)N(Cc1ccccc1)c1ccccc1 +Cc1cccc(N2C(=O)c3cccnc3C2CC(=O)NC2CC2)c1 +Fc1ccc(OCCc2nc3c(s2)CCCN3)cc1 +CSc1ccc(CNC(=O)c2c(-c3ccncc3)noc2C)cc1 +COC(=O)N=c1[nH]c2ccc(SC3CCCC3)cc2[nH]1 +Cc1noc(NC(=O)c2cc3c(F)cccc3s2)n1 +Cc1ccc(CNc2nc(-c3ccco3)nn2S(C)(=O)=O)o1 +CCN(CC(C)C)C(=O)Nc1cccc(S(C)(=O)=O)c1 +CC1(C)C(NC(=O)Nc2cc(-c3ccccc3)on2)C2CCOC21 +Cn1c(=O)c2ccc(C(=O)Nc3c(F)cccc3F)nc2n(C)c1=O +O=C(NCC1CCC(C(=O)NC2CC2)CC1)c1cc2cccn2cn1 +CCN(CC(C)C#N)C(=O)c1ccc(=O)n(CCOC)n1 +Nn1cc(-c2ccccc2)nc1SCc1cccnc1 +O=C(Nc1cc(F)ccc1SCC(F)F)C1CCOCC1 +Cc1noc(C)c1COC(=O)COc1cccc(N2CCCC2=O)c1 +CC(Nc1ccc(NC(=O)NC2CC2)cc1)c1nc(C2CC2)no1 +Cc1ccc(C)c(OCCCN2CCN(S(C)(=O)=O)CC2)c1 +Cc1c(CN2CC3OCCN(C)C3C2)c(=O)n(-c2ccccc2)n1C +CNC(=O)NCC1CCC2(CCN(C(=O)c3ccccc3)CC2)CO1 +CCOc1ccccc1C(C#N)NCc1ccc(OC)cc1 +COc1cccc(NC(=O)CNc2cccc(NC(C)=O)c2)c1 +O=C(CCc1cccs1)Nc1ccccc1CO +O=C(Cn1c(=O)oc2ccccc21)NCCOc1ccccc1 +Cc1nnc(SCCCNC(=O)c2cnccc2C)s1 +Cc1ccoc1CN(C)Cc1nc(-c2cccnc2)no1 +CCN(CCO)C(=O)c1cn(-c2ccc(C)cc2)nc1-c1ccccc1 +CC(NC(=O)c1csnn1)C(O)c1ccc(Br)cc1 +Cc1ccc(-n2cccn2)c(-c2nccn2Cc2nnc3n2CCC3)c1 +COC(=O)c1cc(C(C)C)nc(N2CCCCC2)n1 +CS(=O)(=O)c1ccccc1C(=O)Nc1ccc(C#N)c(Cl)c1 +CN(C)c1ncccc1C(=O)NC1CCc2ccccc21 +CCc1ccc(OCC(=O)NC(C)(C)C(=O)OC)cc1 +COC(=O)CC1C(=O)NCCN1Cc1cccc(F)c1F +CCCNc1nc(-c2cn(C)nc2C)cc(C(F)(F)F)n1 +CC(=O)c1ccc(C(=O)N(C)Cc2ccccn2)cc1 +CCOc1ccc(NC(=O)CSc2nncs2)cc1F +CN(CCc1ccc(F)cc1)Cc1noc(-c2ccccc2)n1 +Cc1cnc(C(=O)NCc2cn3ccccc3n2)cn1 +Cc1nc2c3ccccc3nc(SCC#N)n2n1 +CC(C)CCC(C)NC(=O)c1nn(C)c(=O)c2ccccc12 +CCOC(=O)C1CCN(C(=O)c2cccc(OCC(F)F)n2)CC1 +Cc1nnc(NC(=O)CCSc2ccc(N)cc2)s1 +CC(Nc1snc2ccccc12)C(=O)NC(C)(C)C +CCC(C)(C)C(=O)NCc1nnc(C)n1C1CC1 +NC(=O)c1ccc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)cc1 +CC(=O)NCCC(=O)Nc1cccc(S(=O)(=O)NC2CC2)c1 +NS(=O)(=O)c1ccc(NS(=O)(=O)c2ccccc2F)cc1 +CCN(CC)C(=O)CSc1nc2cc(C)ccc2[nH]1 +O=C(NCc1nnc2n1CCC2)N1CCCCC1Cc1ccccc1 +CC(C)Oc1ncccc1NC(=O)c1cccc(OCC(F)F)n1 +CC(C)NC(=O)CN1CC(C)Sc2ccccc21 +Cc1ccccc1NC(=O)C1CCCN1C(=O)c1cccc(F)c1 +CN(CC1CCCCO1)c1nc2c(c(=O)[nH]c(=O)n2C)n1C +CCOc1ccc(OCC)c(NC(=O)NC(C)c2ccncc2)c1 +COc1ccc(C(=O)CCC(=O)N2CCCCCC2)cc1C +O=C(c1cnccn1)N1CC2COCC2(COCc2ccncc2)C1 +O=C(NCc1ccccc1)c1n[nH]c2ccccc12 +O=C(COc1ccc2c(c1)OCO2)N1CCC(O)CC1 +CC(C)CC(=O)N1CCN(C(=O)c2ccco2)CC1 +CCNC(=O)c1ccc(=O)n(-c2ccc(OC)cc2)c1 +CSc1ccc(CN(C)C(=O)c2cc(Cl)c3c(c2)OCO3)cc1 +CC1CN(C(=O)NCc2ccncc2)c2ccccc21 +CCC(NC(=O)c1cn(C)nc1-c1cccs1)c1nccs1 +CCc1ccc(C(C)CC(=O)OCC(=O)NC)cc1 +CSc1nc(CSc2ccccc2)nc(N)c1C#N +O=C(c1cnn(Cc2ccccc2)c1)N1CCC2(CC1)OCCO2 +CN1CC(=O)N2CC(NC(=O)NCCc3ccccc3)CC2C1=O +CCN(CCCNC(=O)C1CC=CC1)c1ccccc1 +O=C(NC1CC2C(=O)N3CCCC3C(=O)N2C1)c1cccc(Cl)c1 +COC(=O)c1ccc(C(=O)NCCOc2ccc(C)cc2)cc1 +O=C(Nc1ccccc1C(=O)Nc1ccccc1O)c1cccs1 +CC1CN(Cc2ccc(C#N)o2)CC(c2ccccc2)O1 +COc1ccc(CC2C(=O)Nc3ccccc32)cc1OC +COCCN(Cc1ccsc1)C(=O)NC(C)C +Cc1cc(C)cc(OCCC(=O)N2CCOCC2c2ncon2)c1 +COCCN1CC(C(=O)NC2CCCC(C)C2)CC1=O +CN(C)C(CN1CCCCC1)=C1N=C(c2ccccc2)OC1=O +CCN(CC)C(=O)CCC(O)c1ccc(C(C)(C)C)cc1 +O=C(NCc1noc(-c2ccco2)n1)c1ccc[nH]c1=O +C=CCSc1nnc(NC(=O)Cc2c(C)noc2C)s1 +CCOC(=O)c1nc(NCCC(C)C)c2c(C)noc2n1 +CC(C(=O)NCC(=O)Nc1cccc(F)c1)c1ccsc1 +O=C1c2cc(Br)ccc2-n2c1nc1ccccc1c2=O +CNS(=O)(=O)c1ccc(SCC(=O)NC2CCCCC2)cc1 +COc1ccc(C)cc1NCC(=O)NCCC(C)C +Cc1cnc(NC(=O)CSc2nc3ccc(Cl)cc3[nH]2)s1 +CC(C)(C)OC(=O)NCCc1c[nH]c2ccccc12 +CCN(CC(C)C#N)C(=O)Cc1cccc(OCC#N)c1 +O=C(Nc1ccccc1C(=O)NC1CC1)c1ccc(NC2CC2)nc1 +CCc1noc(-c2cccnc2-n2ncc(C(=O)OC)c2C)n1 +CN(CCC(F)(F)F)C(=O)c1cc(-c2ccco2)[nH]n1 +c1ccc2c(c1)nc1nccc(-c3ccc4c(c3)OCO4)n12 +CN(CCc1ccc(F)cc1)C(=O)c1cccc(OC(F)F)c1 +COCC(=O)N1CCN2C(=O)N(Cc3ccccn3)CC2C1 +COC(=O)CN(Cc1ccccc1C)S(=O)(=O)N1CCCC1 +Cc1ccc2[nH]c3nc(SCC(=O)NC4CC4)nnc3c2c1 +COc1cc(NC(=O)CCC(C)C)ccc1N1CCCC1=O +Cc1cc(C(=O)OCCn2ccccc2=O)ncn1 +O=C(Cc1cccs1)NCCc1csc(-n2cccn2)n1 +Cn1ccnc(NC(=O)COc2ccc(C(C)(C)C)cc2)c1=O +CC(=O)Nc1nc(C(=O)NCCc2ccc(Cl)cc2)cs1 +COc1cc(C(C)=O)ccc1OS(=O)(=O)c1cc(F)ccc1C +CCNC(=O)c1ccccc1NC(=O)c1ccc(OCC)cc1 +COc1ccc(-c2nc(CNC(=O)CC(C)(C)C)no2)cc1 +CCn1c(SCC(=O)NC(C)(C#N)C2CC2)nc2ccccc21 +COc1ccc(NC(=O)Cc2cn(C)c3ccccc23)cc1 +Cc1c(-c2noc(-c3ccc(C#N)cc3)n2)nnn1-c1ccccc1 +CNC(=O)c1nnsc1-n1nnc2ccccc21 +COc1ccc(C2CCCN2Cc2nc3ccsc3c(=O)[nH]2)cc1 +Cc1nc(C)c(CC(=O)NCc2ccc(OC(C)C)nc2)c(=O)[nH]1 +CC(=O)N1CCCN(C(=O)c2ccccc2SCC=C(C)C)CC1 +CC1CCN(c2cc(-c3ccccc3)ncn2)CC1 +COCCNC(=O)c1cc(C(C)C)nc2onc(C)c12 +COC(=O)Nc1ccc(NC(=O)C(O)c2ccccc2)cc1 +CCN(Cc1ccccc1C#N)C(=O)c1ccccc1 +CCCNC(=O)c1cnc2sc(N3CCCCCC3)nn2c1=O +CN(Cc1ccc(OCC2CCCO2)cc1)Cc1nccs1 +O=C(c1ccc(Cl)cc1)N1CC(c2nc(-c3cccnc3)no2)C1 +Cc1ccccc1CC(=O)Nc1c(C)nn(C)c1C +O=C(Nc1cccc(Oc2cnccn2)c1)c1ccc2ccccc2n1 +Cc1cnccc1CN(C)C(=O)C1CCOc2ccccc2C1 +COc1ccccc1NC(=O)N1CCN(CC(=O)N2CCCC2)CC1 +CCCCn1nnnc1CSc1ccc(N)nc1 +COC(=O)c1cccc(N(CCO)S(C)(=O)=O)c1 +NC(=O)c1cccc(OCC(=O)Nc2cc(C3CCCCC3)[nH]n2)c1 +CN1CCN(C(=O)c2ccc(-c3cccs3)s2)CC1 +N#Cc1ncn(CC(=O)N2CCN(Cc3cccs3)CC2)n1 +CN(Cc1ccco1)c1c(-c2ccc(Cl)cc2)c(=O)c1=O +CS(=O)(=O)NC1CCCN(C(=O)c2ccc(-n3cccc3)cc2)C1 +Cc1ccc(OC(C)C(=O)Nc2ccc(N)cc2C)cc1C +Fc1cc(F)c2c(c1)C(c1ccc(F)nc1)NCC2 +CC(C)COc1cccc(-c2cc(C#N)c(=O)n(C)n2)c1 +CCN(CC(C)C(=O)OC)S(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +COc1ccc(-c2cnc(Cn3nc(-c4ccco4)oc3=O)o2)cc1 +CCc1ccccc1NC(=O)CN(C)C(=O)c1ccccc1O +CCc1nc(CNc2cc(C)ccc2NC(C)=O)cs1 +COCC(C)CNC(=O)Nc1ccc(C(N)=O)cc1C +O=C(CO)N1CCc2[nH]nc(C(c3ccccc3)c3ccccc3)c2C1 +Cc1noc(C)c1S(=O)(=O)NC(CO)Cc1ccccc1 +O=C(NCCC(O)c1ccco1)c1ccccc1C(F)(F)F +Cc1noc(C(C)OC(=O)C(C)(C)Oc2ccc(F)cc2)n1 +CCOCC(=O)Nc1ccc2c(c1)NC(=O)CS2 +CC(CNC(=O)Cc1ccc[nH]1)Oc1ccc(Cl)cc1 +Cc1nc(C)c(CC(=O)N2CCN(Cc3ccsc3)CC2)s1 +Cc1ccc(S(=O)(=O)C(O)c2c[nH]c3ccccc23)cc1 +Cc1ccc(C(=O)NCCCN(C)c2ccccc2)cc1N +CSc1ccc(CN(C)C(=O)c2cc(C)nn2C)cc1 +COc1cccc(-c2nc(-c3ccncc3)no2)c1OC +CCCC(=O)N1CCCC(C(=O)N(C)Cc2nccn2C(F)F)C1 +CCOc1ccccc1CCC(=O)Nc1ccc(C)cc1C(=O)NC +CC(C)c1ccsc1C(=O)C(C#N)c1nc2ccccc2n1C +O=C(Nc1ccc(C(F)(F)F)cc1)C1CC2CCC1O2 +O=c1ccc(-c2nc(C3CC3)no2)cn1Cc1c(F)cccc1Cl +O=C(C1CC(=O)N(c2ccc(F)cc2)C1)N1Cc2cncnc2C1 +COCc1ccccc1NC(=O)c1cccnc1SC +O=C(c1cccc(F)c1)N1CCCC(c2cc3cccnc3[nH]2)C1 +CC(C)CC(=O)N1CCN(c2ncccc2C(N)=O)CC1 +N#Cc1ccccc1NC(=O)c1ccc(-n2cnnn2)cc1 +CCN(C(=O)c1ccc(C#N)cn1)c1ccc(C#N)c(Cl)c1 +Cc1ccc2ncc(C(=O)Nc3cccc(C#N)c3)n2c1 +COCCOCC(=O)Nc1ccc2c(c1)OC(F)(F)O2 +CC(C)C(=O)N1CCC(C(=O)NC2CCCCC2C)CC1 +COc1cccc(OC)c1C(=O)NCc1ccncc1 +CCC(C)NC(=O)CN(C)S(=O)(=O)c1ccc(OC)c(Cl)c1 +Cc1ccc(NC(=O)c2nc(C)n(-c3ccc(Cl)cc3)n2)cc1C +CN(C)S(=O)(=O)N1CCC2(CC1)CN(Cc1cccnc1)C2=O +CC(OC(=O)c1cc2ccccc2s1)C(=O)N1CCCC1 +O=C(NCCn1ccnc1-c1ncccn1)Nc1cccc(Cl)c1 +CC(C)C(=O)Nc1cccc(NC(=O)C2CC3CCC2O3)c1 +CCN1CCN(C(=O)CC(NC(C)=O)c2ccc(C)cc2)CC1 +O=C(NC1CCN(c2c(F)cccc2F)C1=O)c1cscn1 +COc1ccc(S(=O)(=O)NCCc2ccccc2)cc1NC(C)=O +Cc1nn(C(C)(C)C)c2nc(N)c(C(=O)NC(C)(C)C)cc12 +Cc1c(-c2ccccn2)c(O)nn1-c1ccc(F)cc1 +COC(=O)c1ccc(C2NCCc3c(OC)cccc32)cc1 +COc1ccccc1C(C)NC(=O)NCc1nc(-c2ccco2)n[nH]1 +Cc1ccc(C)c(NC(=O)Cn2c(C)nnc2-c2cccc(C#N)c2)c1 +CN(CC1CCOCC1)C(=O)NCC(C1CC1)C1CC1 +COc1cc2ncn(Cc3ccccc3)c(=O)c2cc1O +COc1ccc(C(O)CNc2ccc(C#N)cc2)c(OC)c1 +CCNc1ccccc1C(=O)NCCC(=O)OC +COc1cc(N2CCCC3(CC(Nc4cccnc4)CO3)C2)ncn1 +CC(C)(C)NC(=O)c1cc(C2CC2)nc2ccccc12 +COC(=O)c1c(C)[nH]c(C(=O)N(C)CCc2ccc(F)cc2)c1C +CCc1noc(CC)c1CC(=O)Nc1nc(C(C)=O)cs1 +O=C(CCCc1nc(-c2ccncc2)no1)c1ccc(F)cc1 +Cc1ccccc1CC(=O)Nc1cccc(C(=O)N2CCCC2)c1 +CC(C)C(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1 +COc1ccc(OC)c(NC(=O)Cc2ccccc2C)c1 +CCOC(=O)c1cn[nH]c1NC1OC(=O)c2c1ccc(OC)c2OC +C#CCOc1ccc(NC(=O)c2cc(C)n(-c3ccccc3)n2)cc1 +COCCNC(=O)Nc1cc(F)c2nc(N3CCCC3)ccc2c1 +CCCS(=O)(=O)c1ccc(NC(C)C(N)=O)cc1 +Cc1nnc(SCc2nc3ccccc3[nH]2)n1-c1ccccc1 +CNC(=O)CN1CCN(C(=O)Cn2nnc(-c3ccccc3)n2)CC1 +CCCNC(=O)c1ccnn1COc1ccc(Cl)cc1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2nc3ccc(C)cc3s2)c1C +Brc1cccc2c1CCNC2c1ccoc1 +Cc1ccc(CNC(=O)CCc2c(C)nc3nc(N)nn3c2C)s1 +O=C(CCS(=O)(=O)c1ccc(F)cc1)NCc1ccccc1F +N#Cc1ccc(NC(=O)c2cccc(OCC(N)=O)c2)cc1 +Cc1ccc(C)c(C(=O)CCC(=O)N2CCC(O)CC2)c1 +CCC(=O)N(Cc1cccs1)Cc1cc2ccc(C)cc2[nH]c1=O +Cc1n[nH]cc1NC(=O)CCCNC(=O)C1CC1 +Cc1ccc(S(=O)(=O)NCC2(O)CCCC2)cc1Cl +COCCNC(=O)C1COC(=O)N1Cc1cccc(OC)c1 +Cc1nc(SCC(O)CO)n(C2CCCCC2)c1C +CC1CN(C(=O)c2csc(-c3ccco3)n2)CC(C)O1 +Cc1cccc(Oc2ccc(S(C)(=O)=O)cc2S(C)(=O)=O)c1 +CCN(C(=O)COc1ccc(NC(=O)OC)cc1)C1CCCCC1 +Cc1nc(C)c(CNCC2(c3ccccc3)CC2)s1 +Cc1cccc(N2CCN(CCNC(=O)C3COCCO3)CC2)c1 +Cn1c(=O)c2c(nc(NCCO)n2CC(N)=O)n(C)c1=O +CC1CCCCN1C(=O)CSc1nc(-c2cccnc2)n[nH]1 +COC(=O)CC(C)NC(=O)Cc1cc(Cl)ccc1Cl +CC(C)CNS(=O)(=O)c1cc(Cl)ccc1Cl +CC(=O)Nc1ccccc1OCc1nnc(-c2cccs2)o1 +Cc1ccccc1OCCC(=O)N1CCC(Nc2cccnn2)CC1 +O=C(c1ccsc1)N1CCCC1c1nc2ccccc2[nH]1 +Cn1cnc2c(-c3ccc(Br)cc3)csc2c1=O +O=c1ccc(-c2nc(Cc3cccs3)no2)c[nH]1 +Cc1noc(C2(NC(=O)C3CCC(C)CC3)CCCCC2)n1 +CCC(C)C(=O)Nc1ccc(Cl)cc1C(N)=O +CCC(=O)Nc1ccc(C)c(NCc2nc(C(C)C)no2)c1 +CCC(NC(=O)Cc1ccccc1OC)c1nc(-c2ccccc2)c[nH]1 +O=C(NCCN1CCCS1(=O)=O)C1(c2ccccc2)CCC1 +Cc1oncc1C(=O)NCC1CCN(C(=O)c2ccccc2F)CC1 +Cc1nc(-c2cccs2)sc1CNC(=O)C1CCCO1 +Cc1nn(CC(=O)N2CCCOCC2)c(C)c1N +O=C(NCCNc1ncccn1)c1cc(F)ccc1Br +C=C(C)Cn1c(SCC(=O)OC)nc2c1c(=O)[nH]c(=O)n2C +CC(C)CN1CC2CC(C(=O)N3CCCC3)C(C1)O2 +CC(Cc1ccco1)NC(=O)NC1CCSc2ccccc21 +COc1cc(C2CC(O)=Nc3c2cnn3C)ccc1O +CCOC(=O)CCC(=O)c1cc(C)c(OC)cc1C +NS(=O)(=O)c1cccc(NC(=O)N2CC(N3CCOCC3)C2)c1 +COc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +COc1cc(OC)cc(C(c2c(O)n[nH]c2C)C(C#N)C#N)c1 +OCCCc1nc2cc(F)ccc2n1Cc1ccccc1 +CCCc1cc(NC(=O)Cc2c(CC)noc2CC)n[nH]1 +OCc1c(-c2ccc(F)cc2)nc2cc(Cl)ccn12 +Cc1nnc(NC(=O)NCc2nnc3n2CCC3)s1 +CN(C(=O)CSc1nnnn1C)C1(C#N)CCCCC1 +O=C(COC(=O)C1CCC1)Nc1cccc(Br)c1 +Cc1ccc(-c2nnco2)cc1NC(=O)NC1Cc2ccccc2C1 +O=C(c1c2c(nc3ccccc13)CCC2)N1CCN(CC(F)F)CC1 +COc1ccc(C(=O)Nc2nc(C)c(-c3ccccc3)s2)nn1 +CC(=O)NCCNC(=O)c1nccc2c(N)c(C)ccc12 +Cc1nccc(C(=O)N2CCOC(c3nc(C(C)C)n[nH]3)C2)n1 +CC1CCN(c2nc3nccc(-c4ccncc4)c3c(=O)[nH]2)CC1 +Cc1cc(CNS(=O)(=O)c2ccccc2Br)c(C)o1 +Cc1noc(CNC(=O)N2CC(Oc3ccccc3Cl)C2)n1 +CN(C)S(=O)(=O)N1CC(n2cc(-c3ccccc3)nn2)C1 +COc1cccc(CNC(=O)Nc2ccc(C#N)cc2)c1OC +COCC(=O)N(Cc1ccc2c(c1)OCO2)C1CCC(C)CC1 +CC(=O)NC(C(=O)OCc1ccc(F)cc1Br)C(C)C +COc1ccccc1CC(=O)NCc1ccnc(OC2CCC2)c1 +Cc1ccccc1C(CC(=O)N(CC(N)=O)C1CCCC1)NC(N)=O +Cn1ccc(CNC(=O)NC2Cc3ccccc3C2)c1 +Cc1cc(NC2CCC(O)CC2)n2c(nc3ccccc32)c1C#N +O=C(NCc1ccccc1)NCC(O)C(F)(F)F +CCC(O)CN(c1ccccc1)S(=O)(=O)c1ccccc1OC +CN(CCc1ccc(C(C)(C)C)cc1)C(=O)CCC#N +COCCN(C(C)COC)C1CCCCCC1C#N +Cc1sc2ncn(CCC(=O)Oc3ccccc3)c(=O)c2c1C +COC(=O)Cn1cc(NC(=O)c2cc(Cl)cn2C)cn1 +Cc1nc(C)c(C#N)c(SCc2nnc(-c3cccs3)o2)n1 +COc1ccc2c(c1)CC(C(=O)Nc1cccc(C(C)=O)c1)CO2 +COc1cccc2cc(C(=O)NCCCOC(C)C)oc12 +COc1ccc(NC(=O)NCc2ccnn2C)cc1N1CCCC1=O +CCCCNC(=O)CNC(=O)c1cc(C)cc(C)c1 +Cc1cc(F)ccc1C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +Cc1ccc(CNC(=O)Cc2ccc(C)s2)cc1 +CCCNC(C#N)c1cc(OC)c(OC)c(OC)c1 +Cc1ccc(C(=O)NCC(O)c2cccc(OC(F)F)c2)nc1 +CCc1c(C(=O)Nc2ccc(F)cc2)cnn1-c1ccccn1 +O=C(Cn1ccnn1)Nc1ccc(-c2cn3ccccc3n2)cc1 +COc1ccc(C(C)NC(C)C(=O)N2CCOCC2)cc1 +CCCc1c(CO)nnn1-c1ccc(S(N)(=O)=O)cc1 +COc1cccc(-c2noc(Cn3ncc4ccccc43)n2)c1 +CCC1CCC(NC(=O)c2ccc(S(=O)(=O)NC)cc2)CC1 +NC(=O)C1CCN(C(=O)CSc2ccc(F)cc2)c2ccccc21 +Cc1ccc(NC(=O)CCNC(=O)C2CC3CCC2O3)nc1 +OCc1nnn(Cc2ccc(F)cc2)c1COc1ccccc1 +CCc1nc(CC(=O)N2CCCCC2C)cs1 +CN(C(=O)c1ccc(Cl)c(S(C)(=O)=O)c1)c1ccccc1 +OCc1ccc(N2CCN(c3ccccc3)CC2)nn1 +CCn1cnnc1CNS(=O)(=O)N1CCCC1c1ccco1 +CC(=O)NCCCSc1nnc(C2CC2)n1C1CC1 +CCn1cnnc1C1CCCCN1C(=O)c1ccc(OC)nc1OC +COc1ccc(OC)c(Nc2ncnc(N(C)C)c2N)c1 +Cc1nc(-c2ccc(-c3noc(C4CCC4)n3)cc2)cs1 +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)Nc1cc(C)cc(C)c1 +CCc1noc(CN(C)C(=O)C(C)CC2CCCC2)n1 +Cc1nc(C)c(CC(=O)NC(c2ccccc2)c2ccccc2)c(=O)[nH]1 +CCOc1ccccc1C(=O)NCc1nn(C)c(=O)c2ccccc12 +CCOCC(=O)N(C)Cc1cn(-c2ccccc2)nc1-c1ccccc1 +FC(F)(F)Oc1cccc2c1CCNC2c1ccncc1 +CC(C)(C)OC(=O)NC1(CNC(=O)Cn2cncn2)CCCCC1 +Cc1cc(C(=O)N2CCCC(c3ccccc3)C2)[nH]n1 +CC(CC#N)N1CCN(C(C)c2nc(-c3ccccc3)no2)CC1 +Cc1cc(C(=O)OCCNc2cccnn2)c2c(C)nn(C)c2n1 +CCCCC(NC(=O)c1c(O)cccc1O)c1cccnc1 +Cc1csc(CNC(=O)c2ccc3c(c2)OCCCO3)n1 +c1ccc2sc(CN3CCCC(n4cccn4)C3)cc2c1 +Cc1ccc(C(=O)NCCCCN2CCOCC2)cc1 +O=C(CN1C(=O)COc2ccc(O)cc21)Nc1ccccc1 +CC(C)CC(NC(N)=O)C(=O)Nc1ccc(OC(F)F)c(F)c1 +CC1CCCN(C(=O)CNC(=O)c2ccc(-c3ccccc3)cc2)C1 +COc1cc2ncnc(NCc3ccc(Cl)cc3)c2cc1OC +CNC(=O)Nc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1 +Cc1ccc2nc3c(cc2c1)CN(Cc1ccc(F)cc1)C(=O)CO3 +COC(=O)C(C)CN(C)S(=O)(=O)c1cnn(-c2ccccc2)c1 +CCN1CCN(Cc2nc(-c3cc(F)ccc3F)oc2C)C(C)C1=O +O=C(Nc1nccs1)c1ccc(CSc2ccccc2)o1 +CNC(=O)c1ccc(CNC(=O)c2ccccc2C)cc1 +NC(=O)C1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 +O=C(NCc1cccnc1)c1csc(Nc2ncccn2)n1 +O=C(NCc1ccc(C(F)(F)F)cc1)C1CCCC1 +O=C(Nc1cccc(OCCc2cccnc2)c1)c1ccco1 +Clc1cccc(OCCC2OCCO2)c1Cl +COc1ncccc1C1NCCc2c(Cl)cc(F)cc21 +CCCc1nc2oc3c(N(C)CCO)ncnc3c2c2c1CCCC2 +Clc1cc2c(cc1Cl)C(c1nc[nH]n1)NCC2 +COc1ccc(F)cc1S(=O)(=O)NC1CNC(=O)C1 +CCS(=O)(=O)NCC(=O)NCC1CCC(C)(C)CC1 +CNC(=O)c1cccc(CNc2ccc(F)c(NC(C)=O)c2)c1 +C=CCC1(CO)CCCN(C(=O)C2(c3ccccc3F)CC2)C1 +Cc1cc(C(=O)NCCc2ccco2)c2c(=O)n(C)c(=O)n(C)c2n1 +CCCCn1cc(C(=O)c2cc(F)ccc2O)cc(C#N)c1=O +COc1nc(C(=O)N2CCn3cccc3C2C)cc2ccccc12 +O=C(Cc1ccc(F)cc1F)Oc1ccc2cn[nH]c2c1 +CC1COCCN1CCOc1ccccc1Br +CCC(C)NC(=O)C(C)NC(=O)c1ccc(Br)cc1F +Cc1cc(NC(=O)NCC2CCC(C(N)=O)O2)c2ncccc2c1 +Cc1ccc(-n2ncc3c2NC(=O)CC3c2ccc3c(c2)OCO3)cc1 +Cc1nc(CC2CCN(C(=O)CN3CCOC3=O)CC2)no1 +NC(=O)CCCNC(=O)Nc1cc(F)ccc1F +COCCN1CCN(S(=O)(=O)c2ccc(C)s2)CC1=O +CCOc1ccc(F)c(C(=O)NCCc2ncc(CC)s2)c1F +O=S(=O)(Cc1ccccc1Cl)NCc1ccoc1 +Cc1nn(CCCC(=O)NCc2ccccc2)c(=O)c2noc(C)c12 +Cc1nc2ccc(NC(=O)NC(C)c3ccncc3)cc2o1 +CCOC(=O)c1c(NC(C)=O)sc2c1CCC(CC)C2 +CC(=O)c1cccc(NC(=O)c2ccc(NC(=O)C(C)C)cc2)c1 +COc1cccc(NC(=O)NCCCn2ccc3cccnc32)c1 +COc1ccccc1OC1CCN(c2ncnc(C)c2C)CC1 +CC(=O)NC1CCCN(C(=O)NCCc2ccccn2)C1 +O=c1[nH]ncc(N2CCOCC2)c1SCc1ccccc1 +CCCCc1nnc(SCc2cn3c(C)cc(C)nc3n2)n1N +O=S(=O)(NCc1ccc2c(c1)OCO2)c1ccc(Cl)cc1F +CCN(C(=O)CNc1ccc(F)cc1F)C1CC1 +CCOc1cc(C#N)cc(Cl)c1OC(=O)Cc1ccc(C)nc1 +O=C(NCC(=O)N1CCCc2ccccc21)c1ccnc2ncccc12 +Cc1cc(C)n2nc(C(=O)N(C)CCC#N)nc2n1 +Cc1cc(C(=O)Nc2ccc3c(c2)COC3)ncn1 +C#Cc1cccc(NCc2ccccc2C(N)=O)c1 +CCOC(=O)c1sc2ncn(C(C)C(=O)OC)c(=O)c2c1C +CC(C)CNC(=O)C1CC(=O)N(C)C1c1cccnc1 +N#CC1CN(Cc2ccc(F)c(C(F)(F)F)c2)CCO1 +Cc1cc(C(=O)NCC(C)(C)c2ccncc2)c(C)o1 +COc1ccccc1NC1CCN(C(=O)c2ccc(=O)n(C)c2)CC1 +Cc1cccc(N)c1C(=O)N1CCN(CCO)CC1 +CCC1COCCN1C(=O)c1ncc(F)cc1F +CCc1nnsc1C(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +O=C1Nc2ccc(Cl)cc2C1Cc1ccsc1 +FC(F)(F)Cn1cc(NCc2ccsc2)cn1 +CNC(=O)CN(C)C(=O)c1cc(OC)ccc1N +Fc1cnc(NC2COC3(CCN(c4nncs4)C3)C2)nc1 +CC(C)N(CCC#N)C(=O)COc1ccccc1N +CCC(CC)N(CCO)C(=O)c1cccc(O)c1 +CC(Oc1cccc(C(C)(C)C)c1)C(=O)Nc1ncc(C(N)=O)s1 +COc1cccc(CN(C)C(=O)CNc2ccc(F)cc2)c1 +CCOc1ccc(N(CC(N)=O)S(C)(=O)=O)cc1 +CCCOc1cccc(NC(=O)Nc2cnn(CC3CCCO3)c2)c1 +COCCN1CCN(C(=O)c2ccc(C)[nH]c2=O)CC1=O +Cn1cc(C(=O)NCCNC(=O)c2ccccc2)c(C(C)(C)C)n1 +CCNc1nnc(SCc2nc3ccccc3o2)s1 +CC(C)NC(=O)Nc1ccc(Oc2cccnc2)nc1 +CC(=O)N1CCN(CCC(=O)Nc2ccc(Cl)cc2F)CC1 +Cc1ccncc1NC(=O)N1CC(C)OC(c2ccc(F)cc2)C1 +COc1cccc(C(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)c1OC +COc1ccc(C(C)NS(=O)(=O)c2c(C)noc2C)cc1OC +CN(CC(O)C1CC1)C(=O)c1ccc(-c2ccccc2)n1C +COCCCNC(=O)C(C)Oc1ccc2ccccc2c1 +COCCN(Cc1ccccc1)C(=O)c1ccccc1F +O=C(Cc1ccccc1)NCC(=O)Nc1ccc(-c2nc[nH]n2)cc1 +CCOc1ccccc1NC(=O)CNc1ccc(C(=O)N(C)C)cc1 +O=C(NC1CCC(O)CC1)C1(c2ccc(Cl)cc2)CC1 +CCOc1cccc(NC(=O)c2cc(C)n(CC)c2C)c1 +CCS(=O)(=O)c1cccc(CC(=O)N2CCCC2c2ccc[nH]2)c1 +Cc1ccc2oc(C(=O)Nc3ccccc3F)cc2n1 +CCn1ncc(-c2ccc(OC)cc2)c(CC#N)c1=O +COc1cc(C(=O)c2ccccc2C#N)cc(OC)c1OC +Cc1cc(=O)n(C)cc1NC(=O)NC(C)c1ccc(Cl)cc1 +CCc1ccc(OCC(=O)N(C)C(C)C(O)c2ccccc2)cc1 +Cc1nc(NC(=O)C2CCN(c3ccc(C#N)cn3)CC2)sc1C +COC(=O)c1ccc(OC(=O)c2ccc(=O)[nH]c2)cc1 +CNC(=O)c1ccc(CNC(=O)c2cnn(-c3ccncc3)c2C)cc1 +COC1CCN(Cc2ccncc2)C1Cc1ccncc1 +CC(C)c1nc(Cn2cnc(C3CCC3)cc2=O)no1 +Cc1ccccc1NC(=O)CSc1cccc(N)c1 +CCCn1nnnc1COC(=O)c1ccc(-n2cccc2)cc1 +COC(=O)CN1C(=O)CSc2ccc(N)cc21 +COc1ccc(C(C)=O)cc1CC(=O)Nc1cccc(Cl)c1 +COc1ccc(OC)c(NS(=O)(=O)c2c(F)cccc2F)c1 +CCOC(=O)CSc1nnc(C(F)(F)F)n1-c1ccccc1 +CCNC(=O)C(C)NC(=O)NC(C)c1ccccn1 +O=C(c1cccnc1)N(Cc1ccccc1)CC1(O)CCCC1 +Cc1nc(-c2nc[nH]n2)sc1C(=O)Nc1ccc2c(c1)CCC2 +N#CCc1cccc(C(=O)Nc2ncc(C(N)=O)s2)c1 +NC(=O)c1ccc(C(F)(F)F)n(Cc2ccc(Cl)cc2)c1=O +O=C(Nc1ccn(Cc2ccccc2)n1)OCC(F)(F)F +O=C1CN(C(=O)COC(=O)C2CCCCC2)c2ccccc2N1 +CCN(CCC#N)C(=O)COc1cccc(OC)c1 +CN(C)c1ccc(C(=O)NCCOCC2CC2)cc1 +CCCc1n[nH]c(C2CN(CC(O)c3ccccc3)CCO2)n1 +COCC(=O)N1CCCC1C(=O)Nc1ccccc1 +Cc1nc(N)nc(C(C)Oc2ccc(C(C)C)cc2)c1C(N)=O +CCCn1c(SCC(=O)C(C)(C)C)n[nH]c1=O +CN(C)C(=O)c1nccc2c(N)c(Br)ccc12 +Cc1ccc(OCC(=O)N2CCN(c3ncccn3)CC2)cc1 +c1ccc(-n2cccn2)c(CNCc2nnc3n2CCCCC3)c1 +CC(C)c1cccc(NC(=O)c2cn3c(n2)CCCC3)c1 +CCCN1C(=O)C(O)(C(F)(F)F)N=C1c1ccccc1 +Cc1sc(=O)n(CC(=O)N2CCOCC2C2CC2)c1C +Cn1nc(-c2ccccc2)cc1C(=O)NCc1cccnc1 +NC(=O)NCC(=O)NCc1cccc(NC(=O)C2CCCC2)c1 +N#CCCn1c(-c2cccc(N)c2)nc2ccc(F)cc21 +CC(C)NC(=O)c1cc(Cl)ccc1-n1cnnn1 +COc1cc2c(=O)c3c(O)ccc(OC)c3oc2c(OC)c1OC +O=C(COC(=O)c1ccncc1)NCc1ccccc1 +Cc1n[nH]c(C)c1NC(=O)Nc1cccc(C(=O)c2ccccc2)c1 +NC(=O)CCn1nc(-c2cccs2)c2ccccc2c1=O +O=C(NCCNC(=O)c1scnc1C1CC1)c1ccco1 +CC(C)C(NC(=O)c1ccnc2c1OCO2)C(=O)N1CCOCC1 +Cc1ccc(Br)cc1S(=O)(=O)Nc1ccccn1 +COc1ccc(CNC(=O)C2(c3ccccc3)CC2)cc1 +FC(F)(F)c1cccc(NCCCN2CCOCC2)c1 +CC1CN(S(=O)(=O)c2ccc3c(c2)CCO3)C(C)CO1 +Cc1nnnn1-c1ccccc1C(=O)NC1CCCCCC1 +CCCC(=O)N1CCC(C(=O)NCc2ccncc2)CC1 +CC(=O)Nc1ccc(NCc2c(F)cccc2F)cc1 +COc1ccccc1S(=O)(=O)N1CC(C)OC(C)C1 +CCN(CC1COc2ccccc2O1)C(=O)c1ccoc1C +Cc1cc(NC(=O)c2nc3nccc(C)n3n2)n(-c2ccccc2)n1 +Cc1cccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)c1 +Cc1cccn2cc(CNC(=O)c3cccc(Cl)c3)nc12 +Cc1ccc(-n2nc(C)c(NC(=O)c3ccccn3)c2C)cc1 +Cc1ccc(C(=O)Nc2cccnc2N(C)C)cn1 +Cc1ccc(CNC(=O)c2cc3c(C)nccc3[nH]c2=O)cc1 +Cc1ccc(C2COCCN2Cc2cc(F)cc(F)c2)o1 +Cc1nc(CC(=O)Nc2c(C(N)=O)oc3ccccc23)cs1 +COC(=O)c1sc(NC(=O)Cc2ccccc2C)nc1C1CC1 +O=C(CN1CCN(c2ccccc2)C1=O)Nc1ccccc1F +COc1cccc(Nc2ncnc3sccc23)c1 +O=C(Cn1cnc(C2CCC2)cc1=O)NCC1CCC1 +CCOc1cc(CNC(=O)c2ccnc3ccccc23)ccc1OC +O=C(Nc1ccccc1-n1cccn1)c1csnn1 +Cc1cccc(OCC(O)CNC(=O)C2CCC2)c1 +O=C(NCc1ccncc1)c1csc(-c2cc3ccccc3[nH]2)n1 +CCNc1ccc(Br)cc1NC(=O)C(C)c1cccnc1 +CNc1nnc(-c2cc(-c3cccnc3)oc2C)s1 +Cc1nc2cc(NC(=O)c3cccc4cccnc34)ccc2o1 +COCCNC(=O)N1CC(=O)N(Cc2ccccc2)C1 +CC(=O)c1c(C)[nH]c(C(=O)N2CCSc3ccccc32)c1C +COCCn1nc(C(=O)NC(C)Cc2ccc(Cl)cc2)ccc1=O +O=C(CCSc1ccc(F)cc1)Nc1cccc(-c2nnco2)c1 +Cc1n[nH]c(C)c1CNC(=O)CCc1ccsc1 +COC(=O)C(C)NC(=O)NCc1ccc(S(N)(=O)=O)cc1 +O=C(NCCCn1cccn1)N1CCN(Cc2ccccc2)CC1 +COc1ccc2cc(C(=O)NCC(OC)c3cccc(F)c3)[nH]c2c1 +Clc1ccc(-c2noc3c2CN(Cc2cccnc2)CC3)cc1 +CC(=O)Nc1ccc(C#CCNC(=O)Cc2ccccc2Cl)cc1 +O=C(Nc1cnn(-c2ccccc2Cl)c1)N1CCC(O)C1 +CC(NCc1ccc(C#N)cc1F)C(C)n1cccn1 +CCOC(=O)C1CCCN(c2cnn(-c3ccccc3)c2)C1 +COc1ccc2c(c1)CCN2C(=O)c1ccc[nH]c1=O +COCCNS(=O)(=O)c1nc2nc(C)cc(C)n2n1 +CC(COCC(F)(F)F)Nc1cnn(C)c(=O)c1Cl +CNC(=O)Nc1cccc(NC(=O)c2sccc2OC(F)F)c1 +CC1CCCCN1c1c(-c2ccc3c(c2)OCC(=O)N3)c(=O)c1=O +CC(=O)Nc1nc(-c2ccc3c(c2)N(C)C(=O)C(C)O3)cs1 +Cc1cccc(SCC(=O)NCc2ccccn2)c1 +N#CCOc1cccc(CC(=O)N2CCOC3(CCOCC3)C2)c1 +COC(=O)c1c(C)[nH]c(-c2csc(-c3ccsc3)n2)c1C +CC(COc1ccccc1)OC(=O)c1cccnc1 +CC(C)N1CC(C(=O)NCCCn2ccc3ccccc32)CC1=O +O=C(CC1CCCC1)N1CCC(c2nc(-c3cccnc3)n[nH]2)CC1 +CC(C)n1cnnc1SCCn1cc(Br)cn1 +N#Cc1cccc(CS(=O)(=O)NC2CCC(O)CC2)c1 +O=C(NC1CCCC1)c1ccn2c(-c3ccccc3)nnc2c1 +CS(=O)(=O)c1ccc(NC(=O)c2cc3c(s2)CCC3)cc1 +CN(C)c1cccc(C(=O)NCc2ccnc(OC(C)(C)C)c2)c1 +CC(C)(C)C(O)CCNS(=O)(=O)c1cc(F)cc(F)c1 +Cc1ccccc1C(=O)NCC(=O)NC(C)c1ccc(F)c(F)c1 +N#Cc1csc(CCOc2ccc(Cl)cc2)n1 +O=C(NCCC(O)c1ccco1)C1CC(=O)N(c2ccc(F)cc2)C1 +COc1ccc(OC)c(-c2ccc(N)c(=O)n2C(C)C)c1 +Cc1ncc(CN(C)S(=O)(=O)c2c(C)nn(C)c2C)s1 +CCn1cc(NC(=O)C2(c3ccccc3Cl)CCOCC2)cn1 +CC(=O)c1c(SCC(=O)NC(C)C(C)C)nc(=O)[nH]c1C +Cc1csc(=O)n1CCSc1ccc(O)cc1 +CCCc1noc(CNc2ccc(C(=O)N(C)C)c(C)c2)n1 +CNC(=O)c1cc(NC(=O)NCCO)ccc1Cl +Cc1ccc(NC(=O)NCCn2c(=O)oc3ccccc32)cc1 +CCc1nn(C)c(NC(=O)N2CCN(c3ncccn3)CC2)c1CC +Cn1c(NCC2CC=CCC2)c(C#N)c(=O)n(C)c1=O +COc1cc(OC)cc(OCc2nc(C(C)=O)cs2)c1 +CC(C(=O)Nc1ccc2ccccc2c1)N1CCN(C(=O)CO)CC1 +C=CCn1nnc(S(=O)(=O)c2ccc(Cl)cc2)c1N +CC(O)CCNc1nnc2c3ccccc3n(C)c2n1 +CC(C)n1c(=O)[nH]c(=O)c2c1nc(NCCCO)n2C +COc1ccccc1C=CCN1CCN(c2nc(C)ns2)CC1 +NC(=O)C1CCCN(S(=O)(=O)c2ccc(S(N)(=O)=O)cc2)C1 +CCOC(=O)C1CCN(C(=O)c2ccc(-c3nc(C)no3)cc2)CC1 +COCc1nnc(NC(=O)CNc2c(C)cccc2C)s1 +Nc1cc(N)nc(SCCC(=O)Nc2ccc(Cl)cc2F)n1 +O=C(Nc1cccc2ncccc12)N1CCCCCC1 +NC(=O)CC1CCCN(C(=O)Cc2c(F)cccc2F)C1 +CC(=O)NCc1ccc(C(=O)OCC(=O)NC2CCCCC2)cc1 +CCCCC(=O)NCc1nc(C)cc(N2CCCCC2)n1 +CSc1ccc(C(=O)NCc2cccc(NC(C)C)c2)cn1 +Cc1cccc(OCCC(=O)N2CCc3cc(N)ccc32)c1 +CC(=O)N1CC(Oc2nc3c(C(F)(F)F)cccc3s2)C1 +Cc1cc(F)c2c(c1)CCCN2C(=O)Cn1c(C)c(C)sc1=O +CCn1cc(NCc2c[nH]c3ccccc23)c(C)n1 +O=C(Cc1cn2ccsc2n1)N1CC(c2ccncc2)C1 +CC(=O)Nc1cccc(OCCNC(=O)c2cc(F)ccc2F)c1 +CC(C)c1noc(CCCNC(=O)c2cc3c(s2)CCC3)n1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)Nc2cccc(C)c2)c1 +CC(C)C(Sc1nncn1-c1ccccc1)C(=O)NC(C)(C)C +Cc1cc(C)nc(NCC(O)COc2ccccc2C)n1 +Cc1ccccc1CNc1cccc(OCC(=O)N(C)C)c1 +CCC1CN(C(=O)CCn2ccnn2)CC1N1CCOCC1 +CC1CN(Cc2ccccc2)CCN1S(=O)(=O)c1cncc(F)c1 +COc1ccccc1-c1noc(-c2ccc(-n3ccnn3)cc2)n1 +CN(CCC(F)(F)F)C(=O)c1cc(-c2ccccc2)on1 +CN1CCC(NC(=O)CN(C)c2ccccc2)=NC1=O +Cc1cccc(NC(=O)N2CC(c3nc(-c4cnccn4)no3)C2)c1 +CC(C)N(C)C(=O)c1cncc(C(=O)N(C)C(C)C)c1 +CCC(C)C(C)NC(=O)c1ccnc(SC)c1 +CN(C)C(=O)c1ccc(Cl)cc1NCc1ccc(C#N)cc1 +Cc1ccc(CN(C)C(=O)c2cc3ccccc3[nH]c2=O)o1 +O=C(CCNS(=O)(=O)c1ccc2c(c1)CCCC2)N1CCC1 +Brc1ccc(CNCCc2nnc3ccccn23)cc1 +N#Cc1cc2c(nc1N1CCOC(C(F)(F)F)C1)CCCC2 +COc1ccc(CCNC(=O)Cn2ncccc2=O)cc1 +Cc1ccccc1OCC(=O)Nc1c(C)cnn1CC1CC1 +CC(CC#N)N1CCN(c2ncc(Br)cn2)CC1 +COc1cccc(OCC(=O)NCC#Cc2ccccc2OC)c1 +Cc1ccc(N2CC(C(=O)N(C)CC(=O)NC(C)C)CC2=O)c(F)c1 +N#CCCC(C#N)Cn1cnc2ccc(Br)cc2c1=O +Cc1ccc(-c2nnc3sc4c(n23)CCC4)cc1N +CC(NC(=O)Cn1nc(C(F)(F)F)cc1C1CC1)C(C)(C)C +COc1ccc(CNC(=O)NC2CCN(c3nccs3)CC2)cc1 +CSc1ccc(NC(=O)Cc2cccc(OCC#N)c2)cn1 +c1ccc2nc(N3CCCC3)c(N3CCCCC3)nc2c1 +Cc1cc(C)c(OCCCN2CCCS2(=O)=O)cc1C +Cc1nc2ccc(NC(=O)N3CCC4(CC3)OCCO4)cc2o1 +Cc1ccc(OCc2nc(C(=O)N3CCCC3)cs2)cc1C +O=C(c1cc2ccccc2o1)N1CCN(C(=O)C2CC=CCC2)CC1 +CCC1CN(C(=O)c2ccc(Cl)c(Cl)c2O)CCO1 +CCCS(=O)(=O)N(C)C(=O)c1ccc(CC)o1 +Cc1cc(NC2c3ccccc3CC2O)n2nc(C(F)(F)F)nc2n1 +Cc1cccc(C2NCCc3c2ccc2ccccc32)n1 +CN(C(=O)c1ccc(F)c(F)c1)C(C#N)c1ccccc1F +COc1ccc(C(=O)NCc2cc(F)cc(F)c2)cc1 +CCN(C)S(=O)(=O)c1cccc2c1CCNC2 +COc1ccc(CCC(=O)Nc2ccnc(C)c2)cc1Br +COc1ccc(NC(=O)COc2ccc(C)cc2C)c(N)c1 +c1cc2c(cc1CNc1ccc3cn[nH]c3c1)OCO2 +COc1ccc(C(=O)CNC(=O)Cc2ccc(F)cc2)cc1 +O=C(Cc1n[nH]c2ccccc12)N(CC1CCC1)CC(F)(F)F +COC(=O)c1ccc(OC(C)C(=O)Nc2cccc(C#N)c2)cc1 +C#CCSc1nnc(-c2cc(N(C)C)nc(N(C)C)n2)n1C +O=C(CNC(=O)c1ccccc1)NCCc1nc2ccccc2s1 +COCCCC(=O)N1CCC(N2CCNC2=O)CC1 +CCc1ccsc1C(=O)N1CCC(OCc2ccccc2F)CC1 +CC(NC(=O)CNC(=O)OC(C)(C)C)c1ccncc1 +COc1ccc(C(=O)Nc2ccc(C)c(Cl)c2)c(N)c1 +CCOC(=O)C1=C(COc2ccccc2NC(C)=O)NC(=O)NC1 +CCCCCC(=O)N1CCCN(C(=O)c2ccccc2Cl)CC1 +O=C(c1cccs1)N1CCCC2(CCN(c3cccnc3)CC2)C1 +Cc1cc(C)n2ncc(C(=O)NC(C)Cn3cncn3)c2n1 +COc1ccc(Cl)c2c1CCNC2c1ccc(F)nc1 +CCn1cc(COc2ccc(Cl)cc2C(C)O)cn1 +Fc1cccc(CC2CN(Cc3cccnc3)CCO2)c1 +Cc1ccc(NCc2n[nH]c(-c3ccco3)n2)cc1 +CCOc1cc(NCc2ccc(F)cc2)nc(CC)n1 +COc1ccc(CC(=O)N2CCNC(=O)C2)cc1F +CN(Cc1ccccc1Br)C(=O)CCc1ccco1 +Cc1cc(NCCNC(N)=O)n2c(nc3ccccc32)c1C#N +CS(=O)(=O)c1ccc2c(c1)ncn2-c1ccncc1 +Cc1ccc(-c2nnco2)cc1NC(=O)c1ccc2c(c1)CCC2 +CC1Oc2c(C(=O)Nc3cccc(OCC(N)=O)c3)cccc2C1C +Cc1nnc2n1CCN(C(=O)CCc1ccc(C3CC3C)o1)C2 +Cc1ccc(Cn2nc(C3CC3)n(-c3ccccc3)c2=O)cc1 +Cc1csc(C(C#N)C(=O)CSc2ccc(F)cc2)n1 +CCn1cc(C(=O)NCc2ccccn2)c(=O)c2ccccc21 +CC(C)Cc1ncc2c(n1)CN(C(=O)C(C)n1cnc3ccccc31)C2 +Cc1ccc(C(=O)NCCOc2ccc(C(F)(F)F)cn2)c(=O)[nH]1 +CC(C)CNC(=O)c1cnn(-c2ccccc2)c1C(F)(F)F +Cc1cc(C(C)(C)C)cc(C)c1-c1nncc(N)n1 +CC(=O)c1ccccc1NC(=O)C(C)OC(=O)c1ccc(O)cc1 +O=C(NC1CN(c2nncs2)CC2CCCOC21)c1cnccn1 +Cc1cc(C)n2ncc(C(=O)N(C)CC(N)=O)c2n1 +O=C(CSc1ncc2ccccn12)Nc1cc(F)ccc1F +CCc1nc(C)c(-c2csc(NCC(C)C)n2)s1 +Cc1occc1C(=O)N(C)c1nc2ccccc2n1C +Cc1ccc(-c2ocnc2C(=O)NCc2ccccn2)s1 +CCC(NC(=O)c1ccc(OC)cc1OC)c1ccccc1 +COc1ccc(-c2cc(=O)[nH]c(-c3ccncc3)n2)cc1N +CC(C)C(CCO)NC(=O)Nc1ccc(N(C)C)cc1C(F)(F)F +CCOc1ccc(NC(=O)c2cc(C)n3nccc3n2)cc1 +CCOc1ccc(F)c(C(=O)NCc2nccc(N)n2)c1F +CC(=O)c1ccc(F)cc1NC(=O)c1ccc(C(=O)NC2CC2)cc1 +COc1ccc(CNC(=O)CSc2nc3cccnc3[nH]2)cc1 +CC(C)CN1C(Cc2cccn2C)C(O)c2ccccc2S1(=O)=O +O=C(NCc1cc(-c2ccc(F)cc2)on1)c1ccco1 +CC(=O)Nc1ccccc1NS(=O)(=O)c1ccc2ccccc2c1 +COc1ccc2nc(-c3ccc(F)c(NC(=O)C4CC4)c3)cn2n1 +CSc1ccc(S(=O)(=O)N2CCCC(O)c3ccccc32)cc1 +Cc1ccccc1S(=O)(=O)N1CCN(CCO)CC1 +Cc1cc(OC(=O)C2CCCCN2S(C)(=O)=O)ccc1Cl +CC(C)(C)n1ncn(CC(=O)Nc2cccc(F)c2)c1=O +O=C(c1cccc(OCC(F)F)n1)N1CCCC(c2cn[nH]c2)C1 +Cc1cc(NC(=O)CSc2cccc3cccnc23)ccc1O +O=C(NCC1Cc2ccccc2O1)c1ccc(F)cc1 +O=C(C1CC1)N1CCCC(N2CCN(c3ccccc3F)CC2)C1 +CC(C)NS(=O)(=O)c1ccc(NC(=O)C(C)(C)C)cc1 +CC(C)(C)OC(=O)NC(CO)C(=O)Nc1ccc(F)cc1 +C#CCS(=O)(=O)c1ccc(OCC(C)C)cc1 +CCOC(=O)CCC(C)NC(=O)Nc1ccc(Cl)cc1C +COCC(C)NC(=O)N(C)Cc1cccc(C#N)c1 +Cc1cc(CN2CCOC(c3nccs3)C2)ccc1F +O=c1ccc(C2NCCc3ccc4[nH]ccc4c32)n[nH]1 +CS(=O)(=O)N1CCN(CCNC(=O)c2cnccn2)CC1 +O=C(c1cc2ccccc2oc1=O)N1CCOc2ccccc21 +CC(CCc1ccco1)NC(=O)c1ccc(CNC(N)=O)cc1 +O=C(CCC(=O)NC12CC3CC(CC(C3)C1)C2)NCc1cccs1 +Cc1ccc(CNC(=O)c2cccc(-c3nnnn3C)c2)cc1 +CC(=O)N1CCC(NC(=O)NCCN(C)C(=O)OC(C)(C)C)CC1 +CNS(=O)(=O)c1ccc(CCC(=O)N2CCCCCC2)cc1 +Cc1ccc(C(C)NC(=O)CCc2ccccc2F)o1 +CC(Cn1cccn1)NS(=O)(=O)N1CCCCCC1 +COc1ccc(OC)c(NC(=O)C2(C#N)CCCC2)c1 +COC(=O)C1CCC(C(F)(F)F)N(C(=O)OC(C)(C)C)C1 +COc1ccc(C(=O)N2CCCc3c(Cl)ccc(OC)c32)nn1 +O=C(Cn1nnn(-c2cccs2)c1=O)c1ccc2c(c1)OCO2 +N#Cc1cc(-c2ccncc2)n(-c2ccc(Br)cc2)n1 +CC(C)c1nc2scc(-c3cccs3)n2c1N +CC(C)Oc1nccc(OC2CC2)c1S(N)(=O)=O +COc1ccc(NC(=O)c2cccc(N3CCCC3=O)c2)cc1 +CCn1nc(C)c(C(=O)Nc2c(C(=O)N(C)C)nn(C)c2C)c1C +Cc1ccc2c(c1)CCN2C(=O)CC(C)c1c(C)n[nH]c1C +Cc1ccccc1NC(=O)CSc1ccc(-n2nccc2C)nn1 +Cc1cnc(NC(=O)c2nc(C3CC3)n(-c3ccccc3)n2)s1 +CC(C)c1ncncc1C(=O)NCCNc1cccc(F)c1C#N +Cc1onc(-c2cccnc2)c1C(=O)NCc1ccc(F)cc1 +Cc1nc(NCCO)c2cccc(N)c2c1Br +CCC(C)NC(=O)C1CCN(c2cc(OC)cc(OC)c2)C1=O +Cc1c(C(=O)NCC(C)O)sc2cccc(F)c12 +O=C(NC1CCC(O)CC1)C1(c2ccccc2)CC1 +Cc1cccc(C(=O)NCC(Cc2ccc(F)cc2)C(N)=O)n1 +Cn1cc(C2c3ccccc3C(=O)N2CC2CCCO2)c2ccccc21 +Cc1ccc(NC(=O)c2ccc(SCc3cccnc3)cc2)nc1 +CCNC(=O)NC1CCC(OC(=O)c2ccc(OC)cc2)CC1 +CCSc1ccccc1NC(=O)CSc1nnc(CC)n1N +CC(=O)c1cc2c(cc1NC(=O)CCc1cccs1)OCO2 +COc1ccc2c(c1OC)C(=O)OC2Nc1ccccc1C#N +Cc1c(C(=O)N(C)C(C)C)cnn1-c1ccc(Br)cc1 +CC1CCCC(C)N1C(=O)Cn1cnc2cc3c(cc21)OCCO3 +O=C(NC1CCC1)c1ccc(S(=O)(=O)NCc2ccncc2)cc1 +O=C1CN2Cc3c(cc(Cl)c(Cl)c3Cl)NC2=N1 +Cc1csc(CCNS(=O)(=O)c2cnn(-c3ccccc3)c2)n1 +CC1(C)CC(=O)c2sc(NC(=O)c3cn[nH]n3)nc2C1 +Cc1ccc(C(O)CCC(=O)NCc2ccncc2)cc1C +CS(=O)c1ccc(C(=O)NCc2ccc(F)cc2)cc1 +Cc1noc(C2CC3OCCC3N(C(=O)c3ccsc3)C2)n1 +CC(C)c1ccccc1NC(=O)COc1cccc(N)c1 +NCC(=O)c1ccc(C(Cl)(Cl)Cl)cc1 +CCNC(=O)NCCSc1ccc(Cl)cc1 +CC(Oc1ccc(C#N)cc1)c1nc(-c2ccc(C#N)cn2)no1 +CCCCc1ccc(NC(=O)c2ccc(C)nc2N)cc1 +CN(C)C(=O)CN(C)C(=O)CCNC(=O)c1cccs1 +CCCNC(=O)CCNC(=O)Nc1ccc(C(C)=O)c(C)c1 +CCOc1ccc(C(=O)Nc2ccc3c(c2)OCO3)nn1 +CCc1nnc(NC(=O)NCCCN2CC(C)OC(C)C2)s1 +CC=Cc1ccc(OCc2nnnn2C2CC2)c(OC)c1 +CCOC(=O)c1cnc(SC)nc1-c1ccc(F)c(CO)c1 +Cc1c(Cl)cccc1NC(=O)NC(C)C(=O)N1CCCCC1C +O=C1NCCN1C1CCCN(c2cccc(C(F)(F)F)n2)C1 +Cc1noc(COCC(=O)Nc2ccc(Cl)cc2Cl)n1 +CN(CC(=O)NCC(C)(C)c1ccncc1)c1ncnc2[nH]cnc12 +COc1ccc(OC(C)C(=O)NCc2ccco2)cc1 +CC(NC(=O)COc1cccc(C(F)(F)F)c1)C(C)n1cncn1 +Cc1cc(C)nc(N2CCCC3(CCC(=O)N(CCO)C3)C2)n1 +C=CCCOC(C)C(=O)Nc1nc(-c2ccc[nH]2)cs1 +CC(C)(C)c1nc(CNC(=O)Nc2cccs2)no1 +CC(C)Cc1ncc2c(n1)CN(c1cc(NC(C)C)ncn1)C2 +CCN(C)C(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +CCN(CCC#N)S(=O)(=O)N1CC(C)CC(C)C1 +CCN(CC(=O)NC(C)c1ccccc1)S(=O)(=O)c1ccccc1 +O=C(CCOc1cccc(Cl)c1)NCc1ccoc1 +CN1C(=O)COc2ccc(C(=O)Cn3cc(N)ccc3=O)cc21 +CC(=O)c1cccc(Nc2ncccc2C(N)=O)c1 +Cc1nc(-c2ccccc2)sc1CNC(=O)C(C)C +CC1CN(C(=O)NCC(C)(C)N2CC(C)OC(C)C2)CCO1 +Cc1ccc(CNS(=O)(=O)c2cn[nH]c2)cc1 +Cc1ccc(C(C#N)N(C)C(=O)c2ccco2)cc1 +CCCc1nc2c(N)cccc2n1CC(=O)N1CCCCC1 +Cc1cc(C(F)(F)F)nn1C(C)C(=O)NC1CCCCC1C +CC(C)N(C)S(=O)(=O)NCc1cccc(NC(=O)C2CCC2)c1 +COCc1cc(N2CCOC(c3nccs3)C2)n2ncnc2n1 +Cc1nc(NC(=O)c2cccc(-c3nnnn3C)c2)sc1C +Fc1ccc2ncnc(N3CCCC(CN4CCOCC4)C3)c2c1 +CC(=O)N1CCC(NC(=O)N2CCCC2c2ccsc2)CC1 +CCCN(CCC)C(=O)CC1C(=O)N=C(c2ccncc2)N=C1C +COC(=O)c1ncc(Br)c2c(N)ccc(C)c12 +CCNc1ncc(Br)cc1S(=O)(=O)NC1CC1(C)C +CCOC(=O)Cc1nc(-n2cccc2)sc1CC +O=C(Cc1cccc(O)c1)NCc1cccnc1-n1ccnc1 +Cn1ncc(Cl)c1CNCCc1c[nH]c2ccc(F)cc12 +Cc1cc2nnc(SCc3nc(-c4ccco4)no3)n2c(C)n1 +Clc1ccc(NCc2nnc(C3CC3)o2)c(Cl)c1 +NC(=O)C1CCCN(C(=O)c2ccccc2Oc2cccnc2)C1 +CC(C)n1c(C2CCCN(C(=O)Nc3cccs3)C2)nn(C)c1=O +COc1cc(NC(=O)C(C)OCC(F)(F)F)cc(OC)c1 +Cc1ccc(OCC(=O)N2CCN(S(C)(=O)=O)CC2)cn1 +O=C1CCC(C(=O)NCc2ccccc2Cn2cccn2)N1 +CN(C)C(=O)CN1CC2=C(C1=O)C(c1ccc(F)cc1)NC(=O)N2C +Cc1ccccc1-c1noc(CNc2ccccc2C(N)=O)n1 +Cc1cnc(NC(=O)CNC(=O)c2cc3ccccc3[nH]2)s1 +Cc1ccnc2nc(C(=O)Nc3cccc(N(C)C(C)C)c3)nn12 +O=C(c1c[nH]c2ccccc12)N1Cc2cncnc2C1 +CCCCCCNC(=O)c1ccc2c(c1)NC(=O)CS2 +O=C(c1cc[nH]n1)N1CCCC2(CC(Nc3ncc(F)cn3)CO2)C1 +CC(C)n1c(=O)oc2cc(S(=O)(=O)N(C)C)ccc21 +O=C(NCC1(O)CCCC1)Nc1c(F)cccc1F +CCn1ccc2ccc(NC(=O)c3cnn(-c4ccccc4)c3C)cc21 +CC(C)c1nnc(NC(=O)CSc2nccc(C(F)(F)F)n2)o1 +Cc1ccc(C)c(S(=O)(=O)N(C)CC(=O)NC(C)C)c1 +Cc1cccc(CC(=O)OCC(=O)NCc2ccc(F)cc2)c1 +CCOc1ccc2nc(Sc3ccc(N)cc3)[nH]c2c1 +CCOC(=O)C1N=C(C)C(CCC(=O)NC2CCCC2)=C1C +Cc1c(N)cccc1NC(=O)C(C)Sc1ccccc1 +O=C(NCc1ccco1)c1nc(COc2ccc3c(c2)OCO3)no1 +CC(NC(=O)c1cccc(OCc2ccccc2)c1)C(N)=O +CC(=O)c1ccc(NC(=O)C2CCCCN2C(C)=O)cc1C +OCCn1ncc2c(NCC(O)c3ccccc3F)ncnc21 +Cc1noc(C)c1COC(=O)CCc1nc2ccccc2c(=O)[nH]1 +CCNc1c(F)cccc1C(=O)NCCC(F)(F)F +CCc1onc(C)c1NC(=O)NC(C)c1ccncc1 +O=C(NCc1ccoc1)Nc1cccc(C(=O)N2CCOCC2)c1 +CCOc1ccc(C(=O)Cn2cnc(C#N)n2)cc1 +CCCCOc1nc(C)nc(NCC2CCCO2)c1N +O=C(COCC1CCCO1)N(Cc1cscn1)c1ccccc1 +CCCCc1nc2c(sc3nc(C)cc(C)c32)c(=O)n1N +CCOC(=O)c1cc(Cl)c(N)c(Br)c1 +Cc1nn(C(C)(C)C)c(C)c1S(=O)(=O)N(C)Cc1ccccn1 +O=C(Cc1ccsc1)N1CCC(O)C1Cc1ccncc1 +CC(C(=O)NC1CCCC1)N1CCN(c2ccc(C#N)cn2)CC1 +CC(=O)NC(C(=O)Nc1cc(Br)ccc1C)C(C)C +Cc1nnc(C(C)S(=O)(=O)c2cc(C(C)(C)C)ccc2C)o1 +CC1CN(C(=O)COc2ccc(C#N)cc2)CCO1 +Cc1ccccc1N1CCN(C(=O)c2ccc3ncccc3c2)CC1 +CC1CCC(N(C(=O)COc2ccccn2)C2CC2)CC1 +CCc1onc(C)c1NC(=O)C(C)OCc1ccccc1 +Cc1ccc(N2CC(C(=O)NC(C)(C#N)C(C)C)CCC2=O)cc1C +O=C(NCc1cccc(F)c1)Nc1nccs1 +CCN1CC(CN(C)C(=O)NCc2ccccn2)Oc2ccccc21 +c1ccc(CCNCc2ncc(-c3ccccn3)s2)nc1 +CCc1cc(=O)n(CCNC(=O)Nc2cccs2)cn1 +CC(NC(=O)c1cccs1)C(=O)Oc1ccc2c(c1)CCC(=O)N2 +O=C(CCc1ccccc1)Nc1cccc(C(=O)NCc2ccco2)c1 +COCCOCC(=O)N(C)c1ccc(Br)cc1C +CC1CN2CCCC2CN1S(=O)(=O)Cc1cccc(F)c1 +CCNC(=O)c1nnn(-c2ccc(Br)cc2)c1C1CC1 +CCOc1ccc(CC(=O)N2CCC(C)CC2C)cc1 +CCNC(=O)CN1CCN(Cc2nnc(-c3cc(C)oc3C)o2)CC1 +COc1cc(C)c(C(C)C)cc1S(=O)(=O)NCC(C)O +CCn1c2c(cc(-c3csc(NC(C)C)n3)c1=O)CCC2 +Cc1nc(C)c(C(=O)N(Cc2ccccn2)c2ccc(F)cc2)s1 +C#CCN(Cc1ccc(C#N)cc1)Cc1ccco1 +COC(=O)C1=C(C)C(C(=O)OCCn2c(C)csc2=O)=NC1C +CC(NC(=O)c1cccc(F)c1)c1ccc2c(c1)OCCO2 +Cc1ccc2[nH]c(=O)c(CN(C)C(=O)c3ccccn3)cc2c1 +Nc1ccc(C(=O)CCC(=O)Nc2ccccc2F)cc1 +CCn1cc(C(=O)NC2CCOC2c2ccc(Cl)c(F)c2)cn1 +Cc1sc(=O)n(CC(=O)N2CCN(Cc3ccccn3)CC2)c1C +COc1cccc(C(=O)N(Cc2ccccc2)CC2CCCO2)c1F +COc1cccc(C(=O)N2CCOc3ccc(N)cc32)c1 +Cc1ccccc1NC(=O)CCc1c(C)n[nH]c1C +C#CCNC(=O)c1sc2cc(F)ccc2c1Cl +COc1ccc(C(=O)N2CCN(C(C)=O)CC2)cc1 +COc1ccc(CCNS(=O)(=O)c2cnn(C)c2C)cc1OC +Cc1cc(N2CCC(=O)CC2)nc(-c2ccncc2)n1 +O=C(Nc1nc2c(s1)COCC2)c1ccco1 +O=C(c1cc2ccccc2o1)N1CCOC(c2ccccc2)C1 +COCC(NC(=O)c1ccccc1OC(F)F)C(N)=O +CN(C)c1ncccc1C(=O)OCc1cc(Cl)c2c(c1)OCO2 +COC(=O)CNC(=O)C1CC(=O)N(c2ccc(C)c(Cl)c2)C1 +O=C(CCNC(=O)c1ccccc1)Nc1cccc(-c2ccn[nH]2)c1 +CC1(NC(=O)Cc2ccc(-n3cnnn3)cc2)Cc2ccccc2C1 +CCOc1cccc(CNC(=O)Cn2ccnc2)c1 +COCCOCC(=O)Nc1ccc2c(c1)-c1ccccc1C2 +O=C(COc1ccc(Br)cc1)Nc1cn[nH]c1 +C#CCNC(=O)NCCc1ccc(OC)c(OC)c1 +Cc1ncsc1-c1nnc(C2CCCN2C(=O)C2CCCCC2)o1 +CC(C)CC1COCCN1C(=O)NC(C)c1ccccn1 +O=S(=O)(c1ccc(F)cc1)c1snnc1-c1ccccc1 +CC(NC(=O)c1ccccc1)C(=O)Nc1cccc(F)c1 +c1cnc2c(OCc3nc4ccccc4[nH]3)cccc2c1 +CCCCOc1cccn2c(-c3cccc(N)c3)nnc12 +CCNC(=O)N1CCN(C(=O)Cc2ccc(OCC(C)C)cc2)CC1 +COc1ccc(C)nc1NC(=O)NCCc1c(C)nn(C)c1C +COc1cc(CN(C)C(=O)NCc2ncn(C)n2)ccc1SC +C=CCC1(CO)CCCN(c2ccc(-c3ccc(F)cc3)nn2)C1 +COc1ccc(C)cc1NS(=O)(=O)c1ccc(F)c(F)c1 +Cn1cc(C(N)=O)cc1C(=O)OCc1ccc(C#N)cc1 +CN(Cc1ccco1)C(=O)Cn1nnc2ccccc21 +CCS(=O)(=O)Nc1ccn(Cc2cccc(Cl)c2)n1 +C=CCn1c(SCC(=O)Nc2ccccc2)nnc1C(F)(F)F +CN1Cc2c(Cl)ccc(N)c2C2(CC2)S1(=O)=O +CC(C)n1nc(O)c2c1NC(=O)CC2c1ccc(F)cc1 +O=C(c1ccccc1)N1CCC2OC(c3nnc(C4CC4)o3)CC2C1 +O=C(CCC1CCCO1)Oc1cccc(Cl)c1 +O=C(c1ccccc1)N1CCCC1c1n[nH]cc1-c1ccncc1 +CN1CCN(C(=O)c2ccc(Br)c(F)c2)CC1 +CC1CCN(C(=O)c2cc(-c3ccncc3)cn2C)CC1 +COC(=O)C1(N(C)C(=O)C(C)OCC2CC2)CCCCC1 +CC(=O)Nc1c(-c2ccc3ccccc3c2)nc2ccccn12 +Cc1ccccc1-c1noc(CN2CC(=O)N3CCCC3C2=O)n1 +COc1cc2nc(-c3ccccc3)c(=O)[nH]c2cc1OC +CCOC1COCC1NC(=O)c1cnc(C(C)C)nc1C +O=C1CCCc2cc(S(=O)(=O)Nc3ccccc3)ccc2N1 +COc1ccc(CNC(=O)N2CCN(Cc3cccnc3)CC2)cc1 +COCCNC(=O)NC(C)c1ccc(NC(=O)c2ccncc2)cc1 +CCn1c(C)cc(C(=O)Nc2cccc(SC(=O)N(C)C)c2)c1C +Cc1ccc(C(=O)Cn2nc(-c3ccc(F)cc3)oc2=O)cc1C +Nc1cccc(-c2nnc(CCC3CCCCC3)o2)c1 +O=C1C(N2CCOCC2)C2CCCC=C2N1Cc1ccccc1 +O=C(c1ccncc1)N1CCC(c2cccc(C(F)(F)F)c2)C1 +CCc1noc(CC)c1CC(=O)N1CCN(C)c2ccc(F)cc21 +Cc1ccc2ncc(C(=O)NC3CCCc4occc43)n2c1 +Cc1ccc(CNC(=O)N2CCN(c3cnccn3)CC2)n1C +COCCOc1ccc(CNC(=O)NC2CCc3ccccc32)cn1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCCc1cccnc1 +CCN1CCN(C(=O)COc2cc(C)c(Cl)c(C)c2)CC1 +Cc1ccnn1-c1ccc(C(=O)N(CC2CCOC2)C2CC2)cc1 +O=C(COc1cc(=O)n2c(n1)SCCC2)c1ccccc1 +CCC1CN(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)CCO1 +CC(Nc1ccn(C)n1)c1nc2ccccc2s1 +COc1ccc(C)cc1NC(=O)c1nc2ncccn2n1 +Cc1csc(N(CC(F)(F)F)C(=O)CCc2cnn(C)c2C)n1 +COc1ccc(OC)c(C(CO)Cc2ccccn2)c1 +CC(C)CNC(=O)CCNC(=O)c1cnc2c(c1)NC(=O)CO2 +Cc1nc(Oc2ccc(Cl)c(Cl)c2)c2cnn(C)c2n1 +C=CCN(CC=C)C(=O)c1cccc(C(=O)OC)c1 +O=C(Cc1ccc(Cl)c(Cl)c1)OCC(=O)C1=NC=CC1 +CCOC(=O)c1ccc(NC(=O)c2ccnc(SC)c2)cc1 +Cc1cc(C(=O)N2CC(OCC(=O)N(C)C)C2)nn1-c1ccccc1 +CNC(=O)c1ccccc1OCC(=O)N1CCCC1c1cccs1 +N#Cc1ccc(CSc2ccccc2C(=O)NC2CC2)cc1 +O=C(Cn1ncc2c(Cl)cccc21)NC1CCCC1 +Nc1ccc2c(c1)N(C(=O)c1ccccn1)CCS2 +Nc1nccnc1C(=O)NC1CCc2ccccc21 +COc1cc(CNCCc2ccc3c(c2)OCO3)cc(OC)c1 +Cc1ccc(OCC(=O)N(C)C2(C#N)CCC2)c(C)c1 +CC(=O)Nc1ccc(F)c(NC(=O)C2CC=CC2)c1 +C=CCOc1ccc(OCc2noc(-c3scnc3C)n2)cc1 +O=C1NCC(=O)N2CCN(C(=O)c3cccc(F)c3)CC12 +N#CCOc1c(Br)cccc1Br +COc1cc(OC)c(-c2cnoc2N)c(OC)c1 +CC(=O)c1cccc(NC(=O)CSc2nnc(C)n2N)c1 +CC1(C)CC1(C(=O)NCCNc1cccnc1)c1ccc(F)cc1 +COc1ccc(CN2CCN(C(=O)C(C)n3cccn3)CC2)cc1 +CN1C(=O)Cc2cc(NC(=O)c3ccccc3F)ccc21 +O=C(Oc1ccc(=O)n(-c2ccccc2)n1)c1cccs1 +Cc1noc(C)c1CC(=O)Nc1nc(-c2ccccc2)ns1 +O=C(c1ccco1)N1CCc2n[nH]c(-c3ccc(F)cc3)c2C1 +c1ccc(CCc2n[nH]c(-c3ccccc3-n3cncn3)n2)cc1 +Cc1csc(SCc2nc(-c3ccccn3)no2)n1 +NC(=O)C1CCC(c2ccccc2C(F)(F)F)O1 +CC(Oc1ccc(Br)cc1)C(=O)NC1CCC(O)CC1 +Cn1c(N)nnc1SCC(=O)Nc1ccccc1Cl +CCS(=O)(=O)N1CCN(C2CCCCC2)CC1 +CCCN(CCC)C(=O)c1ccccc1NC(C)=O +Cc1cccc(N(CCC(N)=O)CC2CCCC2)c1 +CCN1CC(C(=O)NCc2nnc3n2CCCCC3)CC1=O +Nc1ccc(F)c(C(=O)Nc2cc(F)cc(F)c2)c1 +Cc1noc(COCC(=O)N(C)CCC(C)C)n1 +Cc1ccoc1C(=O)NCC(O)c1ccc(Cl)cc1 +COc1ccccc1C1CC1NC(=O)NC1COc2ccccc21 +CC(=O)c1ccc(OCC(=O)Nc2ccc(Cl)cc2)cc1 +CC(C)C(=O)NCCNC(=O)CCc1c[nH]c2ccccc12 +O=C(Nc1cnn(Cc2ccccc2)c1)c1cc2ccccn2n1 +COc1cc(-c2noc(-c3cc(C4CC4)[nH]n3)n2)cc(OC)c1OC +Cc1cc(NC(=O)c2cccc(NC(=O)C3CCCO3)c2)[nH]n1 +CCOC(=O)NC1CCN(C(=O)c2cnns2)CC1 +Cc1noc(C)c1CN1CC2(CCN(C(=O)C(C)(C)C)CC2)CC1=O +CCCNC(=O)CCNC(=O)NCC(=O)N1CCCc2ccccc21 +COc1ccc2nc(C(=O)Nc3ccccc3C(C)=O)ccc2c1 +OCCn1ccc(-c2ccc(-n3cncn3)cc2)n1 +Cc1sc(=O)n(CC(=O)NCCCC(N)=O)c1C +CCOC(=O)C1CCCN(C(=O)Nc2cc(C)ccc2F)C1 +CCn1nc(C)cc1C(=O)Nc1cc(C)nn1-c1ccccc1 +Cc1ccc(Cn2nnc(C(=O)NCc3ccc(F)cc3)c2N)cc1 +CC(=O)c1ccc(NC(=O)c2ccc3nncn3c2)cc1 +CSc1ccc(NC(=O)C2COc3ccccc3O2)cc1 +COc1ccc(N2CC(C(=O)N3CCCCCC3)CC2=O)cc1 +CCOc1cc(C(=O)Nc2ccon2)cc2occc12 +CCN(c1ccncc1)S(=O)(=O)CCC1CC1 +OCC1=C(CO)C2C3(CCCC3)C1C1C3CCC(C3)C12O +Cc1cccc(C(CNC(=O)C(C)NC(N)=O)N2CCOCC2)c1 +CC(CNC(=O)CCc1ccsc1)c1cccs1 +CC(C(=O)N1CCCCCC1)N1CCN(c2ccc(O)cc2)CC1 +O=C(c1ccc(F)cc1)N1CC2CC3CC(C2)CC1C3 +COC(=O)CCN(Cc1ccncc1)C(=O)C1CC2C=CC1C2 +CCCN(CC(=O)NC)c1ccc(F)cc1C(C)O +O=c1ccc(Br)cn1Cc1nc(-c2ccncc2)no1 +C=C(C)Cn1cc(CO)c2c(OC)cc(OC)cc21 +CC(C)(O)CCc1cccc(C(=O)NCc2ncc[nH]2)c1 +CCC(C)(C)NC(=O)CCNC(=O)c1ccsc1 +Cc1csc(C(C#N)C(=O)c2ccc(N3CCCC3)c(F)c2)n1 +O=C(COC(=O)c1ccco1)Nc1ccccc1Cl +O=C1CC(C(=O)Nc2nccs2)C(c2ccccc2)O1 +Cc1cc2c(=O)n(Cc3cccc4c3OCCO4)cnc2s1 +CCN(CC(C)C)C(=O)Nc1ccccc1N(C)C +CN1CCC(C(=O)N2CCCCCC2c2ccccc2)CC1=O +COc1ccc(C(=O)NC2CCCc3c2cnn3C)cc1 +c1cncc(-c2ccnc(NCCN3CCc4ccccc43)n2)c1 +CC1CC2CN(C(=O)c3ccc4c(c3)OCO4)CCC2O1 +CC(C)Nc1ncnc(Nc2ccc3c(c2)OCCO3)c1N +CCOC(=O)c1nnsc1NC(=O)c1ccc2c(c1)CCCC2 +N#Cc1ccccc1OCC(=O)OCn1nnc2ccccc2c1=O +Cc1cccc(C(C)NC(=O)Nc2ccnc(C(=O)N(C)C)c2)c1C +CCOC(=O)N1CCN(C(=O)c2cc3c(OC)cccc3n2C)CC1 +C=CCOC(=O)c1csc(-c2ccsc2)n1 +O=C(CSc1nncn1Cc1ccco1)Nc1cccc(F)c1 +CC(NC(C)c1ccc(F)c(F)c1)C(=O)Nc1cccc(C#N)c1 +CN(C)c1ncccc1NC(=O)CCc1ccccc1 +CCCS(=O)(=O)NCC(=O)c1ccc(C(C)C)cc1 +C=CCNC(=O)Nc1cc(Cl)ccc1SC +CCCn1nc(C(=O)OCc2nc3ccccc3s2)ccc1=O +COc1ccc(C(O)C(C)NC(=O)c2cc(C)c(C)s2)cc1 +COc1cccc(CC(=O)Nc2c(-c3ccc(C)o3)n[nH]c2C)c1 +Cc1ccnc(S(=O)(=O)CC2CCN(C(=O)OC(C)(C)C)C2)c1 +COc1ccc(C(O)CNC(=O)c2cccc(Cl)c2)cc1 +CCCNC(=O)Nc1cccc(NC(=O)CCC)c1 +CN(C)C(C(=O)NCc1cc(-c2ccccc2)no1)c1ccccc1 +CC1CCN(C(=O)Nc2ccccc2Cl)CC1 +CCn1nc2ccc(S(=O)(=O)N3CCCCCC3)cn2c1=O +COC(=O)c1ccc2c(c1)C(c1ccc(F)nc1)NCC2 +CCCS(=O)(=O)NCC#Cc1ccc(N(C)C)cc1 +NC(=O)c1cnc(Sc2nnc(C3CC3)s2)c(Cl)c1 +COC(=O)Cn1cnc2c(-c3cccc(OC)c3)cn(C)c2c1=O +CCn1ncc(S(=O)(=O)NC2CCCC2)c1N +CCCCN(CC)C(=O)NCC(=O)N1CCCCC1 +CCc1ccc(CNC(=O)C2CCCN(c3nccc(C)n3)C2)cc1 +Cc1ccc2oc(C(=O)Nc3ncccc3C)cc2c1 +Cc1cc(C2CCC2)nc(NC(C)c2ncnn2C)n1 +COCc1cc(C(=O)Nc2cc(C(C)C)c(O)cc2C)no1 +CC1(C2CCN(C(=O)c3c(Cl)cccc3Cl)CC2)OCCO1 +CCN(Cc1ccncc1)C(=O)c1ccccc1F +O=C(CNC(=O)c1csc2c1CCCC2)c1cccs1 +CC(O)CN1CCN(C(=O)c2cc(Cl)cn2C)CC1 +CC(=O)NCC1NCCc2cc3ccccc3cc21 +O=C(Nc1cccc(CN2CCCC2=O)c1)C1CCC1 +O=C(c1cnc(C2CCCO2)s1)N1CCCc2cccc(Cl)c21 +CCc1nc(CCOc2ccccc2)sc1CC#N +NC(=O)C1CN(CCCc2nc(-c3ccccc3)no2)CCO1 +Cc1cnc(C(=O)N2CCC3(CC3C(=O)N3CCOCC3)C2)cn1 +CNC(=O)COc1ccc(C(=O)Nc2cccc(F)c2)cc1OC +Cc1cc(NC(=O)CCc2nc[nH]n2)c2ncccc2c1 +CC1CCC(Oc2cc(CNC(=O)C3CC4CCC3O4)ccn2)CC1 +CCOC(=O)c1coc(N2CCN(Cc3cccc(F)c3)CC2)n1 +O=C(c1ccc(N2CCCC2)c(F)c1)N1CCCC(C(F)(F)F)C1 +O=C(NCc1ccco1)c1ccc2c(c1)CCCC2 +CCN(Cc1cccc(F)c1)C(=O)c1cccc(C#N)c1 +C#CCN(C(=O)c1cccc(-c2ccoc2)c1)c1nccs1 +c1cnc(N2CCCN(c3nc4ccccc4s3)CC2)nc1 +CCCc1nnc2sc(C(C)Oc3ccccc3)nn12 +Cc1nc(-c2ccc(NC(=O)c3ccccc3)cc2)co1 +O=S(=O)(NCC1(c2ccc(F)cc2F)CC1)c1ccccc1 +O=c1ccc(C2NCCc3ccc4c(c32)CCO4)c[nH]1 +Cc1nnsc1C(=O)NCc1cccnc1N1CCCC(O)C1 +Cc1ccc(Br)cc1S(=O)(=O)N1CC(C)OC(C)C1 +COc1cc(C#CBr)c(OC)c2c1OCO2 +CC(=O)N1CCc2cc(C(=O)N(C)C3CCCc4ccccc43)ccc21 +O=C(CCn1cncn1)NC1CCC2(CC1)OCCO2 +COc1ccc(CN2C(=O)C(C)(C)CS2(=O)=O)cc1C +Cc1ccccc1C(NC(=O)c1ccc(S(C)=O)cc1)C(C)C +CCOc1ccccc1CCC(=O)Nc1nnc(CC)s1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)Nc1ccc(F)cc1 +O=C(Cc1ccc[nH]1)NCCS(=O)(=O)c1ccccc1 +CCOC(=O)N1CCN(c2cc(C)c3nc(N)nn3c2)CC1 +N#Cc1ccc(NC(=O)CCc2ccccc2F)cc1 +CC(C)c1cc(Br)ccc1NC(=O)Cn1cnnn1 +CCc1ncc(C(=O)NCc2ccc(OC)cc2)c(C)n1 +CCOC(=O)CN(C)C(=O)c1cnn2c(C)cc(C)nc12 +CN(CCO)C(=O)c1ccc(-c2cccc(C(F)(F)F)c2)o1 +CC(=O)N1CCC(C(=O)Nc2ccc(N3CCCC3)nc2)CC1 +Cc1nc(CNS(=O)(=O)Cc2ccccc2Cl)cs1 +COC1CCCC1NS(=O)(=O)c1ccc(N)cc1C +CCOC(=O)c1ccc(CNc2nnc(C)c(C)c2C#N)cc1 +CC(C)CNC(=O)Nc1ccc2c(c1)CCC(=O)N2 +CCc1cccc(NC(=O)N2CCN(c3cnn(C)c3)C(=O)C2)c1 +CCc1cc(C(=O)N2CCCCCC2CC(O)c2ccco2)[nH]n1 +NC(c1nc2c(s1)CCC2)c1cccc(F)c1Cl +COC(Cc1ccc2oc(=O)[nH]c2c1)(OC)OC +Cc1ccc(NC(=O)COC(=O)c2n[nH]c3ccccc23)cc1C +CC(Oc1ccc2ccccc2c1)C(=O)NCCCn1ccnc1 +Cc1ccc(NC(=O)C2CCCN2C(N)=O)c(Cl)c1 +Cn1cc(CNC(=O)CCOc2ccc(Cl)cc2)cn1 +CC1(C)C(=O)NCCN1C(=O)c1cccc(C(F)(F)F)c1 +COC(=O)c1cc(-c2cc(OC(C)C)ccc2OC)n[nH]1 +c1csc(N2CCN(c3ncnc4nc[nH]c34)CC2)n1 +CCNC(=O)C(C)NC(=O)c1ccc(OC)cc1OC +CCCOC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +CC(=O)c1ccc(C(=O)Nc2ccc3ncsc3c2)cc1 +CC(c1cccs1)N(C)C(=O)c1cnc2n(c1=O)CCS2 +Cc1cc(C)n(-c2ccc(C(=O)OC(C)C(=O)N3CCCC3)cc2)n1 +CCC(C)NC1=NS(=O)(=O)c2cc(Cl)ccc2N1 +O=C1NC(c2ccc3c(c2)CCO3)Nc2ccc(Cl)cc21 +Cc1cc(CN(C)C(=O)NCc2cccc(OC(F)F)c2)no1 +Cc1ncc(C(=O)N(CCc2ccccc2)Cc2cccnc2)c(C)n1 +Cn1cc(CCC(=O)Nc2cc3c(cc2Cl)NC(=O)CO3)cn1 +CC(CO)CNC(=O)NCc1cccnc1Oc1cccc(F)c1 +CC(C1CC1)N(CC(F)(F)F)C(=O)Cn1ccccc1=O +CCCOc1cc(CO)cc2c1OCC(=O)N2C(C)C(=O)OC +CC(C)(C)CN(CCCO)S(=O)(=O)c1cccnc1 +COc1cccc(NC(=O)c2cnc3ccccn3c2=O)c1 +CCc1[nH]nc(NC(=O)Nc2cccc(OC)c2)c1C +CC(c1cccs1)N(C)C(=O)c1ccc(Cl)c(N)c1 +Cc1cc(C(F)(F)F)nn1C(=O)COc1ccccc1 +CC(O)CNC(=O)c1ccccc1SCc1cn2ccccc2n1 +N#CC(CCC(=O)Nc1cccc(Cl)c1)c1ccncc1 +CCc1noc(C)c1NC(=O)Nc1cnc2c(c1)c(C)nn2C +Cc1ccc(-n2cnnn2)cc1NC(=O)NCC(=O)N(C)C +CC1=C(C(=O)NCc2nc3ccccc3[nH]2)CCO1 +CCc1nnc(NC(=O)c2cc(C3CC3)nn2-c2ccccc2)s1 +CCCc1nnc(NC(=O)c2ccc(-n3ccnn3)cc2)s1 +O=C(NCC(CCO)c1ccccc1)C(O)c1ccccc1 +O=C(NC1CCCCCC1)c1ccc(-c2cncnc2)nc1 +O=C(Nc1ccc(F)cc1F)c1c[nH]c2ccc(Cl)cc2c1=O +Nc1cc(Cl)c(N)c(Br)c1N1CCCC1 +Cc1cc(C)n2nc(C(=O)NC(C)c3ccc4c(c3)CCC4)nc2n1 +Cc1nc(CNC(=O)C2(C)CC2(Cl)Cl)no1 +CNc1nc(-c2ccccc2)cc(C)c1S(C)(=O)=O +CCN(CC(=O)NC(C)(C)C)C(=O)c1cnn(-c2ccncc2)c1C +Nc1n[nH]c2nc3c(c(-c4cccnc4)c12)CCCC3 +CC(COc1ccccc1F)NC(=O)Cc1n[nH]c2ccccc12 +CS(=O)(=O)N1CCN(C(=O)Nc2cccnc2)CC1 +C=CCNc1nc(NC(C)C)nc(N2CCCC2)n1 +Cc1cc(F)ccc1N1CCCC(NC(=O)c2cnn[nH]2)C1 +O=C(Nc1ccc(F)c(F)c1)c1ccc2c(c1)OCCO2 +Cc1cnc(C(NCc2ccc(S(C)=O)cc2)C2CC2)s1 +CC(C)C(=O)NC(CC(=O)N(C)C)c1ccccc1 +CN1C(=O)CN(C(=O)c2ncn(-c3ccccc3)n2)c2ccccc21 +COCc1cc(C(=O)N2CCCC2c2noc(C3CC3)n2)c(C)o1 +CCS(=O)(=O)NCCCNC(=O)N1CCc2ccc(O)cc2C1 +Cc1ccc(C(=O)CN2CC(C)OC(C)C2)cc1N +CCC(=O)NCC(=O)Nc1ccc2nc(-c3ccc(F)cc3)oc2c1 +COC(=O)N(C)CCCC(=O)NC1CC1c1ccccc1Cl +Clc1ccccc1-n1nnnc1-c1ccncc1 +CC1CCCC(C)N1C(=O)N1CCN(C(=O)c2ccco2)CC1 +Cc1ccc(Cn2c(CCCO)nc3ccccc32)cc1 +CC(C)(C)OC(=O)N1CCC(c2ccc(CO)cc2)CC1 +Cc1[nH]c2c(F)cc(Br)cc2c(=O)c1C(C)C +Cn1nc(C2CCN(C(=O)Cn3cncn3)CC2)n(C2CC2)c1=O +O=C1Nc2ccc(-c3ccccc3)cc2C(=O)N2CCNCC12 +CCNc1cc2c(nn1)CCN(C(=O)c1ccccc1-n1cccn1)C2 +CCC(CO)NC(=O)Nc1cccc(C(=O)N(C)c2ccccc2)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)COc1ccccc1O +C=CCN(Cc1ccccc1F)C(=O)c1cn(C)nc1C(C)(C)C +CC(c1ccccc1)N(CC1CC1)C(=O)c1nccn2ccnc12 +CC(NC(=O)NCC(C)(C)c1ccncc1)C1CN(C)CCO1 +CCOC(=O)C1=C(C)Nc2ncnn2C1c1cccc(Cl)c1 +Cc1csc(N(C)C(=O)Cc2ccc(N3CCCC3=O)cc2)n1 +CCOC(=O)C(CC)c1cc(C#N)c(C#N)cc1O +CC(=O)Nc1ccc(NC(=O)N(C)CCOCC2CC2)cc1 +CCCCNC(=O)CCn1ncc2c(C)cccc21 +Cc1cccc(CS(=O)(=O)N2CCc3ccccc32)c1 +c1cnc(N2CCC3(CC2)CC(c2cncnc2)CO3)cn1 +COC(=O)c1c(C)cccc1NS(=O)(=O)c1c(C)nn(C)c1C +Cc1cc(F)c2c(c1)CCCN2C(=O)CCNC(=O)OC(C)(C)C +Cc1sc2ncnc(Oc3ccccc3N)c2c1C +COc1c(Cl)cc(-c2nc(C(C)(C)NC(C)=O)no2)cc1Cl +Cc1nc(C)c(CNC(C)c2ccc(-n3ccnc3C)cc2)s1 +Nc1ccccc1N1CCN(c2ccccc2)CC1 +Cn1cnc2cc(CNC(=O)c3ccoc3)ccc21 +CC1(C)CC(=O)Nc2cc(Br)ccc2O1 +Cc1occc1COC(=O)C1CC1c1ccc(F)cc1 +CC(CNC(=O)NCC(F)(F)F)Nc1ccccc1 +Cc1cccc(-c2noc(C(C)NC(=O)c3ccco3)n2)c1 +CCn1c(NC(=O)CCc2cc(C)cc(C)c2)c(NC)c(O)nc1=O +COCC(O)CNC(=O)Nc1cnn(-c2ccccc2F)c1 +COC(=O)c1ccsc1NC(=O)c1cnn(-c2ccncc2)c1C +COCCc1nnc2n1NC(c1ccc(C)cc1)CS2 +CCc1nn2c(=O)cc(CNc3ccc(C(=O)OC)cc3)nc2s1 +COCc1nc(COc2ccccc2)sc1C(C)=O +Cc1cc(Cl)ccc1OC(C)C(=O)NCC1CCCO1 +CC(C)c1nc(CN(C)c2nnc(C3CC3)o2)cs1 +CCN(CC)C(=O)Cn1cc(C(=O)NCc2ccsc2)nn1 +Cc1nn(C)c(C)c1CC(=O)N(C)c1ccccc1S(C)(=O)=O +Cc1ccc(CCCC(=O)NCC2CCOCO2)s1 +COc1ccc(CNC(=O)c2ccccc2Cl)cc1OC +CC(C)C(O)C1NCCc2c1cccc2C(F)(F)F +Cc1nc(-c2ccccc2)nc2sc3c(=O)n(C(C)C)nnc3c12 +C=CCc1c(O)cc(OC)c2c(=O)c(OC)c(C)oc12 +C=CCNC(=O)c1ccc2c(=O)n(CCOC)c(=O)[nH]c2c1 +CC(C)Oc1ccc(C(O)CCCCO)cc1F +CCOC(=O)C1(O)CCN(C(=O)Nc2cccc(F)c2)CC1 +CCCCc1csc(C(=O)N2CCOc3ncccc32)n1 +COc1ccc(C2NC(=O)NC3=C2C(=O)OC3)cc1 +Cc1cc(C(=O)N2CCN(C(=O)Cc3ccc[nH]3)CC2)c(C)o1 +C=CCSc1nnc(NC(=O)Cc2ccc(OC)cc2)s1 +CCc1nc(CN2CCN(C(=O)CNC(C)=O)CC2)cs1 +CNC(=O)c1cccc(OC(=O)CCc2c(C)nn(C)c2C)c1 +COc1cc(CN2CCc3ccccc3C2CO)cc2c1OCCO2 +CC1CCC(C)N1c1nc2c(cnn2-c2ccccc2)c(=O)[nH]1 +O=C(COc1ccc(-n2cnnn2)cc1)Nc1ccc(F)c(Cl)c1 +CNC(=O)COC(=O)c1ccn(-c2ccccc2F)n1 +CCCCCn1nnc(-c2ccc(C(N)=O)cc2)n1 +CSc1cccc(NC(=O)c2cccc(-n3cnnn3)c2)c1 +CCC(=O)Nc1ccc(O)c(C(=O)N2CCC(n3cccc3)CC2)c1 +O=C(c1ccoc1)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +CC(=O)N1CCC(C(=O)Nc2cc(C)on2)CC1 +CCOc1ccc2c(c1)c(=O)ccn2CC(=O)OC(C)C +CCN(CC)C(=O)c1cc(N)n(-c2ccccc2Cl)n1 +Cn1nc(-c2ccccc2)c2c1CC1CN(C(=O)c3cccs3)CC21 +Cc1nn(C)c(C)c1CNCCc1ccc(C(F)(F)F)cc1 +CCN1C(=O)COc2ccc(S(N)(=O)=O)cc21 +N#Cc1ccc(C(=O)NCC(CO)Cc2ccc(Cl)cc2)nc1 +Cc1n[nH]c(CC(=O)N2CC(C)C(O)(C(C)C)C2)n1 +CC(C)c1nn2c(C#N)c(-c3ccc(F)cc3)nc2s1 +CC(O)CN(CCO)C(=O)COc1ccc(Cl)cc1 +CCCNC(=O)N(CC)Cc1nc(-c2ccc(OC)cc2)no1 +CN(CC(N)=O)C(=O)c1cccc(-n2cc(Br)cn2)c1 +COC(=O)CC(c1ccc(CC(C)C)cc1)C(C)C +COc1ccc(OC)c(NC(=O)c2ccc(-n3ccnn3)cc2)c1 +Cc1cc(C)cc(CCNC(=O)CCn2cnc3ccccc32)c1 +CCn1c(C)cc(=O)c2cc(C(=O)Nc3cccnc3)ccc21 +O=C(CNC(=O)Nc1ccncc1F)Nc1ccc(F)cc1 +Cc1cc(C)cc(C(=O)Nn2cnc3ccccc32)c1 +COCC(C)(C)NC(=O)Nc1ccc(C)cc1F +COC(=O)Nc1ccc(NC(=O)C2Cc3ccccc3C(=O)O2)cc1 +COc1ccc(NC(=O)NC2COc3ccccc3C2)cc1 +CC1(C)CC(=O)c2cnc(NC(=O)CSc3ncccn3)nc2C1 +NC(=O)c1oc2ccccc2c1NC(=O)C12CC3CC(CC(C3)C1)C2 +N#CCn1ccc(NC(=O)Cc2ccc(Br)cc2)n1 +CC(Sc1n[nH]c(=O)n1C)C(=O)c1cccc(Cl)c1 +N#Cc1ccsc1NC(=O)CSc1ncc2ccccn12 +CCN(CC)C(=O)c1cccc(NC(=O)NC(C)c2nc(C)no2)c1 +Cc1cc(C(=O)NC2CCN(c3ccccc3)C2=O)c(C)n1C(C)C +CCC(C)NC(=O)COc1ccc(C(=O)C(C)C)cc1N +N#Cc1ccc(NCCCCn2ccccc2=O)cn1 +CCOc1ccc(C2CCCN2C(=O)NCCc2cnn(C)c2)cc1 +CCOc1ccc(F)c(C(=O)N2CCC(CC(=O)NC)CC2)c1F +Cc1cccc(C(=O)Nc2ccccc2S(=O)(=O)NC(C)(C)C)n1 +CCc1cccc(NC(=O)c2nc(C)n(-c3ccc(Cl)cc3)n2)c1 +O=C(NCc1nncn1C1CC1)C1Cc2cc(F)ccc2O1 +CN1CCN(S(=O)(=O)c2ccc(NC(=O)C3CCC3)cc2)CC1 +NC(=O)c1ccc(S(=O)(=O)NCCOc2ccc(F)cc2)cc1 +CN(C)c1nc(OCC(F)(F)F)nc(N2CCOCC2)n1 +Cc1occc1-c1nnc(SC(C)C(=O)NC2CC2)o1 +COCCOCC(=O)N1CCN(c2ccc(C#N)cc2F)CC1 +CCC(=O)N1CCN(Cc2ccc(-c3ccccc3)o2)CC1 +N#CC(C(=O)c1cccc(N2CCCC2=O)c1)c1nc2ccccc2[nH]1 +Cc1n[nH]c(O)c1C(c1cccc(F)c1)c1c(O)n[nH]c1C +CNc1cnn(-c2cccc(C(F)(F)F)c2)c(=O)c1 +O=C(NCc1cnn(-c2ccccc2)c1)c1ccc(-n2ccnn2)cc1 +CCNC(=O)N1CC(c2nc(-c3ccncc3)no2)C1 +CC(C)OCCCNS(=O)(=O)c1ccccc1Cl +O=C1CCCN1CC(NC(=O)N1CCCC(CO)C1)c1ccccc1 +Cc1cc(C(=O)COC(=O)Cc2cccs2)c(C)[nH]1 +CCC(C)NC(=O)C(C)NC(=O)c1ccc(OC)cc1 +CC(NC(N)=O)C(=O)Nc1cc(C(F)(F)F)ccc1F +Cc1ccc(N2CC(C(=O)N3C(C)COCC3C)CCC2=O)cc1C +CCN(Cc1noc(CC(C)C)n1)C(=O)c1cn[nH]n1 +Cc1cc(C)cc(CC(C)NC(=O)CCC(=O)N2CCC(O)CC2)c1 +CS(=O)(=O)c1ccccc1C(=O)Nc1ccnc2ccnn12 +COc1ccc(C(=O)Nc2c(C)cc(C)cc2Cl)cn1 +CC(NS(=O)(=O)c1cccs1)C(=O)NCc1ccccc1 +COCCN(CC(=O)N1CC(C)OCC1(C)C)C(=O)OC(C)(C)C +CC(=O)Nc1ccc(S(=O)(=O)NC2COC3C(O)COC23)cc1 +CSc1nc2ncc(-c3ccnc(N4CCOCC4)n3)c(C)n2n1 +Cn1cc(-c2ncc(C(=O)N3CCC(n4cccc4)CC3)s2)cn1 +COC(=O)c1ccc(CN(C)C(=O)C2CC(=O)N(C)C2)cc1 +COc1ccc(F)c(NC(=O)NCc2ccc(OC)nc2)c1 +O=C(CCN1CCOC1=O)NCc1ccnc(OC2CCCCC2)c1 +COCc1nc(C)c(C(=O)N(C)C2(C(=O)OC)CCCCC2)s1 +O=C1CC(c2nc(-c3ccncc3)no2)CN1Cc1cccnc1 +Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)c1cccnc1O +O=C(c1ccc2[nH]cnc2c1)N1CCN(c2ccccc2O)CC1 +Cc1csc(NC(=O)Cn2cnc(C#N)c2C#N)n1 +O=C(CCCc1ccc(Cl)cc1)NC1Cc2ccccc2NC1=O +COc1ncccc1C(=O)N1CC=C(c2ccccc2Cl)CC1 +CC(=O)N1CCC(C(=O)NCCN2c3ccccc3CCC2C)CC1 +CN(C)C(=O)CN(C)c1ccc(C#N)c(C(F)(F)F)c1 +FC(F)(F)c1ccc2c(c1)CCNC2c1ccncc1 +O=C(NC1CC1)c1cc(SCc2cccnc2)nc2ccccc12 +CC(Cc1ccc(Br)cc1)NC(=O)CNC(=O)C1CC1 +CC1(COC(=O)c2cc(-c3ccc(Cl)cc3)n[nH]2)COC1 +CCCOc1ccc(C(C)NC(=O)c2ccsc2)cc1OC +CC1CCCCC1N(C)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +CC(CCNC(=O)NCc1cccnc1)c1ccccc1 +Cc1nc(SCC(=O)Nc2cccc(F)c2)oc1C +CCOC1CC(Nc2c(C#N)c(=O)n(C)c(=O)n2C)C12CCC2 +O=C(NCC(F)(F)F)c1cnc(C(F)(F)F)nc1 +COCC1(Cn2cnc(-c3ccccc3)c2-c2nccn2C)CC1 +Fc1ccc2c(c1F)C(c1ncccc1Cl)NCC2 +Cc1ncsc1C(=O)NCC(C)Oc1ccccc1 +CCCCS(=O)(=O)NCC(O)c1ccc2c(c1)CCC2 +O=C(Nc1ccc(Cl)cc1)C1CC(=O)N(Cc2ccccc2)C1 +CS(=O)(=O)NC1CCN(C(=O)c2cc3ccccc3c(=O)[nH]2)CC1 +COc1ccc(OCC(=O)Nc2ccc(N3CCOCC3)cn2)cc1 +CCc1cccc(NC(=O)c2cc(C)n3nccc3n2)c1 +O=C(c1cn2c(n1)CCCC2)N1CCN(c2ccc(F)cc2)CC1 +CCn1c(-c2cn(CCOC(C)C)nn2)nc2ccccc21 +CCOc1ccc(Nc2c(C#N)cnc3ccc(F)cc23)cc1 +N#CCCCn1nc(CO)cc1-c1ccc2ccccc2c1 +CCc1ccccc1OC1CN(C(=O)c2ccc(-c3nc[nH]n3)cc2)C1 +Cc1ccc(S(=O)(=O)N(C)c2ccc(N)cc2F)cc1 +O=C(Cn1ccccc1=O)N1CCCC1c1noc(C2CC2)n1 +CC1(O)CCN(C(=O)c2cncc(Cl)c2)CC1O +Cc1ccc(C)c2c(C)c(C(=O)N3CC=CC3)[nH]c12 +CCn1c(CSc2nncn2C(C)C)nc2c(F)cccc21 +N#Cc1c(N2CCCC2)nsc1-c1ccccc1 +COC(=O)CN(Cc1nc(N)nc(N(C)C)n1)C(C)C +COc1ccc(NC(=O)c2ccnc(N)c2)cc1C +Cc1ccc(-n2cnnc2SCC(=O)OCC(F)(F)F)cc1 +COc1ccccc1C1CC(=O)c2c(C)nn(-c3ccccc3)c2C1 +NS(=O)(=O)N1CCN(C(=O)c2cc3ccccc3s2)CC1 +C=CCOC(C)C(=O)NCCn1c(C)nc2ccccc21 +Cc1cc(C)n(Cc2cccc(NC(=O)c3ccccn3)c2)n1 +Cc1ccsc1C(=O)NCc1ccc(-n2cncn2)nc1 +COCCOc1ccc(F)cc1NC(=O)c1ccncc1F +CCN(Cc1nnc(C)o1)C(C)c1cc2ccccc2o1 +COc1cccc(CNC(=O)Cn2cnc3ccccc32)c1 +CS(=O)(=O)c1cccc(OCC(=O)c2ccccc2)c1 +O=C(Nc1cnc2ccccc2c1)c1ccc(=O)[nH]c1 +CCC1(CCC(=O)NCc2ccsc2)CCC(=O)N1 +c1cncc(Nc2nc(-c3cccc(-n4cnnn4)c3)cs2)c1 +COC(=O)c1cc(Br)cc2[nH]nc(O)c12 +CC(C)c1ccc(C(O)CNC(=O)c2ccnn2C)cc1 +O=C(Cn1nnc2ccccc21)NCc1ccccc1 +CN(Cc1cccc(C(F)(F)F)c1)C(=O)c1ccc2cc[nH]c2c1 +CSc1ncccc1C(=O)NCC(=O)NCc1ccco1 +NC(=O)C1CCCN(C(=O)CNc2cccc(Cl)c2F)C1 +CCc1cccc(OC(C)C(=O)N2CCC(=O)CC2)c1 +CN(C)C(=O)CNc1ccccc1C(=O)N1CCCC(O)C1 +O=C(COc1ccc(Cl)cc1)Nc1ccc2c(c1)OCCO2 +O=C(NC1CC1)C1CCN(C(=O)C2(c3ccccc3)CCC2)CC1 +COc1ccc(OC)c(CN(C)C(=O)c2cccc(C)c2)c1 +COc1cccc(CNc2nnnn2C)c1OCc1ccccc1 +COc1ccc(-c2nc3ccc(CO)cc3o2)cc1 +Cc1ccc(CNS(=O)(=O)c2ccccc2C(F)(F)F)cn1 +CCCN(CC1CC1)C(=O)NCc1ncn(C)n1 +CCCCc1nnc(NC(=O)CCC(C)C)s1 +C=CCNC(=O)COC(=O)c1nn(-c2ccc(F)cc2)c2c1CCC2 +CCc1cc(NCCOc2nonc2C)n2nccc2n1 +CNC(=O)NC1N(C)C(=O)NC(C(C)C)C1(C)C +Cc1ccc(NC(=O)CN(C)C(=O)c2ccc(OC(F)F)cc2)cc1 +N#Cc1c[nH]nc1Cc1ccccc1Br +O=c1[nH]c2ccccc2c(=O)n1CCCc1nc2ccccc2s1 +CCN(CC)S(=O)(=O)c1ccc(Sc2nccnc2C#N)nc1 +CC(Oc1ccc(Cl)cc1)C(=O)C(C#N)c1ccccn1 +CC(=O)c1ccc(C)n(CC(=O)NC2CCCCC2)c1=O +Cn1cc(Cl)c(C(=O)Nc2ccc(Br)cc2F)n1 +CC(=O)N1CCC(CSc2nnnn2Cc2ccccc2)CC1 +c1cncc(N2CCN(Cc3ccccc3Cn3cccn3)CC2)c1 +CN(C(=O)c1ccc(-n2ccnn2)cc1)c1cc(F)ccc1F +Cc1ccc(-n2c(=O)cc(NCC3CCCO3)[nH]c2=O)cc1 +N#Cc1ccc(C(=O)N2CCCC2CC(=O)c2ccccc2)nc1 +CS(=O)(=O)c1ccc(C(O)CNC2CCOc3ccccc32)cc1 +COc1ccc(S(=O)(=O)N(C)CC(=O)NCC(C)C)cc1C +COc1cc2nnn(CCCOc3ccccc3N)c2cc1OC +CC(NC(=O)C1CC(=O)N(c2ccccc2Cl)C1)C1CCCO1 +Cc1n[nH]c(O)c1C(c1ccc(C#N)cc1)c1c(O)n[nH]c1C +COc1ccc(OCC(=O)Nc2ccnn2C(C)C)cc1 +O=C(NCCNC(=O)N1CCCC(O)C1)c1ccc(Cl)cc1 +O=c1[nH]nc(CN2CCC(OCC3CCCCO3)CC2)[nH]1 +CCCC(C)(CO)NC(=O)NC1CCSc2c(F)cccc21 +CCOC(=O)C(C#N)Cc1ccc(Br)cc1 +CN(C)C(=O)CNS(=O)(=O)c1cc(N)ccc1F +O=C(c1cnc(Cc2ccc(F)cc2)s1)N1CCCCC1 +CCc1cc(NC)nc(Cc2ccc(OC)cc2)n1 +Fc1cnccc1C1NCCc2cccc(C(F)(F)F)c21 +CC(NC(=O)c1ccoc1)C(=O)NC1CC1c1cccc(Cl)c1 +CC(Cn1cccn1)NC(C(=O)N(C)C)c1ccccc1 +CCCNC(=O)COc1nc(C)nc2onc(-c3cccc(F)c3)c12 +Cc1c(NCc2cccc3cccnc23)cnn1-c1ccccc1 +O=C(CCCc1nc2ccccc2s1)NCc1ccccn1 +CN(C)c1ncnc(N2CCN(CCO)CC2)c1N +CC(C)NS(=O)(=O)c1ccc(C(=O)Nc2cccc(O)c2)cc1 +CCCNC(=O)CNC(=O)NC(C)c1ccc(-n2ccnc2C)cc1 +CCOC(=O)C1CCCN(C(=O)c2ccc(C(=O)N(C)C)cc2)C1 +CC(C)(C)C(=O)N1CCCC(C(=O)N2CCOCC2C2CC2)C1 +NS(=O)(=O)c1ccc(CCNC(=O)CC2CCCC2)cc1 +CC(=O)c1c(C)nc(C)nc1SCc1ccc(F)c2cccnc12 +O=C(CSc1nc2ccccc2c(=O)[nH]1)NCCO +Fc1ccc(NCc2cn3ccccc3n2)c(F)c1 +CCC(C)(C)NC(=O)c1ccc(-c2csc(C3CC3)n2)cc1 +Cc1ccc2ncc(C(=O)NC3CCN(C)C3=O)n2c1 +CC(C)(C)c1nc(C(=O)Nc2ccc(S(C)(=O)=O)nc2)cs1 +OCCn1nc(Cc2cccc(Cl)c2)nc1CC(F)(F)F +COc1cccc(C(=O)Nc2ccc3c(c2)C(=O)NCC3)c1OC +COc1ccc(NC(=O)NCCc2nc3ccccc3s2)cc1 +CCOC(=O)c1cnn(-c2ccc(Cl)cc2)c1C +Cc1cccc2[nH]cc(CC(=O)NC3CCN(c4ncccn4)CC3)c12 +CNC(=O)c1ccc(NC(=O)COc2ccc(F)cc2Cl)cc1 +CC(C#N)CNC(=O)c1cc(C2CC2)nc2ccccc12 +COCCCn1c(=O)[nH]c2ccc(Cl)cc2c1=O +CC(C)(C)OC(=O)Nc1ncc(C(C)(C)O)s1 +Cn1nccc1C(=O)OC1CN(c2nc3ccccc3s2)C1 +Cc1cccn(CCNc2ccc(Br)cc2)c1=O +Cc1cc(C)c(C(=O)Nc2ccc(Br)cc2F)c(=O)[nH]1 +COc1cc(NC(C)=O)c(Cl)cc1C(=O)NCc1ccc(C)cc1 +Nc1nc(CCC(=O)N2CCCCC2CCc2cccc(O)c2)n[nH]1 +CSc1ccc(OC(C)C(=O)NCCc2cccc(O)c2)cc1 +CCC(=O)N1CCN(C(=O)c2cnn3ccc(C)cc23)CC1 +Cn1ccnc1-c1nccn1-c1ccc(OCC2CCCO2)cc1 +CCOc1cccc(CNC(=O)NCC(O)c2cccc(F)c2)c1 +CC1CCCCN1S(=O)(=O)c1cccc(F)c1C#N +CC(C)CC(C)OC(=O)c1ncn(-c2ccccc2)n1 +Cc1cc(C(=O)CN2CCN(c3nccs3)CC2)c(C)[nH]1 +Cc1ccoc1C(=O)N1CCCCCC1c1ccco1 +N#Cc1ccccc1COc1cccc(C(=O)Nc2nccs2)c1 +COc1ccccc1OC1CN(C(=O)C(C)n2cncn2)C1 +C#CCCOc1cc(Br)ccc1OC +COc1ccc(S(N)(=O)=O)cc1C(=O)NCC1CCOC1 +CCc1nc(COC(=O)C2CCCN2C(=O)c2ccco2)cs1 +CCOC(=O)Cc1nnc(-c2ccc(Cl)cc2)o1 +COc1ccc(CNC(=O)NCc2ccnn2C)cc1OC(F)F +CC(=O)Nc1cc(S(=O)(=O)Oc2ccc(C)cc2)ccc1F +Cc1ccccc1CN(C)C(=O)Nc1ccc(F)cc1C#N +Cc1cccc(C)c1NC(=O)CCSc1ccc(F)cc1 +CCC1CCCN(c2nc3c(cnn3C(C)(C)C)c(=O)[nH]2)C1 +COc1ccccc1CNC(=O)c1cc(C2CC2)nc2onc(C)c12 +CCCn1cnc2cc(NC(=O)COc3ccc(OC)cc3)ccc21 +CCc1cccc(NC(=O)CSc2nnc(C)n2N)c1 +O=C(Nc1cccc(-c2ccn[nH]2)c1)c1ccc[nH]c1=O +CCc1cc(C(=O)NCc2ccc(OC)cc2OC)[nH]n1 +COC(=O)c1ccccc1NC(=O)c1cncn1-c1ccc(F)cc1 +c1csc(N2CCN(Cc3ccccc3N3CCOCC3)CC2)c1 +CCCS(=O)(=O)N1CCN(c2cccc(Cl)c2)CC1 +CCCN1C(=O)C2CCC1CN(C(=O)Cn1cc(C)c(=O)[nH]c1=O)C2 +O=C(NCc1ccco1)NC1CC(=O)N(c2cccc(F)c2)C1 +CCOC(=O)C(C)(NS(=O)(=O)c1cccc(F)c1F)C(C)C +Cc1cc(C)nc(C(=O)Nc2c(C)cccc2C(C)C)c1 +C=CCn1c(=O)c2ccccc2n2c(SCCCC#N)nnc12 +O=C(Nc1ccnn1-c1ccncc1)c1csc(C2CCCO2)n1 +CCC(C)NC(=O)c1ccc2c(c1)nc1n2CCCC1 +COc1ccccc1C(NC(=O)CNC(C)=O)C(C)(C)C +CC(Cn1cccn1)NS(=O)(=O)Cc1ccccc1 +COC(=O)c1ccc(CNC(=O)c2cc3c(C)nn(C)c3s2)cc1 +Cc1nnc(SCC(=O)Nc2ccc(C#N)cc2)s1 +COc1cccc(OCCNC(=O)c2cc(F)ccc2C)c1 +COc1cccc(C(=O)Nc2cccnc2C)c1F +CCC1CN(C(=O)c2cc(S(N)(=O)=O)ccc2C)CCO1 +CCOC(=O)CC(C)CNC(=O)c1nc(C)ncc1Cl +COC(=O)c1n[nH]c(C(C)(C)C)c1Br +COc1ccccc1CNC(=O)CCc1ccc2[nH]ccc2c1 +O=C(NCC1COCc2nc3cccnc3n21)c1cnccn1 +COc1cccc(CCC2CCCN(C(=O)CNC(N)=O)C2)c1 +O=C(c1csc(-c2ccc(N3CCCC3)nc2)n1)N1CCOCC1 +Nc1nc(SCc2cnn(-c3ccccc3)n2)n[nH]1 +C=CCNc1nc(NCc2ccc(C)cc2)c2cnn(C)c2n1 +COc1ccc(C(=O)Nc2cn[nH]c2)cc1-c1ccccc1 +O=C(NC(CO)CO)c1cnn(-c2cccc(Br)c2)c1 +CCOc1ccc(CC(=O)Nc2cc(F)ccc2OC)cc1 +CCOc1cc(C#N)ccc1OC(=O)CC1CCCC1 +Cc1cnn(CC2CCCN2C(=O)c2cc(C)n(C(C)C)c2C)c1 +Cc1ccc(N2CC(C(=O)NCC(C)O)CC2=O)c(F)c1 +CC(CNC(=O)c1cn(CC2CCCCC2)nn1)Oc1cccnc1 +CCc1ccccc1C(=O)N(C)CCc1noc(C)n1 +Cc1nn(CC2CC2)c(=O)n1-c1ccc(Oc2ccccc2)cc1 +CC(C)NC(=O)COc1c(N)cc(Cl)cc1Br +CCOc1ccc(NC(=O)c2cc3ccccn3c2)cc1CO +C=CCCCN(C)C(=O)c1cccn(Cc2cccc(C)c2)c1=O +CCc1ccc(OC)c(-c2cc(C(=O)OC)n(CCO)n2)c1 +COc1ccccc1C(C#N)NC(=O)c1cccc(Cl)c1 +CC(C)c1cc(C(=O)N(C)Cc2ccc3c(c2)OCCO3)n[nH]1 +O=C(CCn1cccn1)NCC1(c2cccc(F)c2)CCOCC1 +O=C1COc2c(cccc2C(=O)N2CCCC2Cn2cccn2)N1 +CS(=O)(=O)c1ccc(CCCCn2cc(N)cn2)cc1 +COc1ccc(NC(C)=O)cc1NCc1noc(-c2ccoc2)n1 +Cc1cc(=O)c(C2CC(C)c3c(cc(C)oc3=O)O2)c(O)o1 +CCCCc1cc(=O)oc2cc(OCC(N)=O)ccc12 +CCOc1cccc(OCCN2CCOCC2)c1 +COC(=O)Cc1nnn(Cc2nc(Cc3ccccc3)no2)n1 +Cc1ccc(-c2nnc(SCC(=O)Nc3nc(C)cs3)o2)cc1 +CC(C)C1CN(S(=O)(=O)C2CC2)CC1Nc1cccc(C#N)n1 +Cc1ccc(F)c(S(=O)(=O)N2CCCCC2CO)c1 +Nc1cccc2c1OCC(=O)N2CC(=O)Nc1ccccc1 +Cc1nc(C)c(-c2nnc(NC(=O)c3ccc(Cl)cc3)o2)s1 +CC(C)CN(C)C(=O)Nc1nnc(C(C)(C)C)s1 +CC12CC=CCC1(C)N(S(=O)(=O)c1ccccc1)C2 +Cn1ccc2c(-c3cc(C(N)=O)ccn3)ccnc21 +COc1ccc(C)cc1NC(=O)COC(=O)c1cnccn1 +CC1CCCCN1C(=O)C1CC(=O)N(C2CCCC2)C1 +CN(C)C(=O)c1cccc(NC(=O)CNc2ccc(Cl)cc2)c1 +CCOc1ccc(NC(=O)NCC2CC2C)cc1F +Cc1nc2c(c(=O)[nH]1)CC1CCC(C2)N1C(=O)C1CCC1 +COc1cc(-c2cnc(=O)[nH]c2)cc(OC)c1OC +Cc1nc(CC(=O)NC(C2CC2)C2CC2)cs1 +CN(CCCNC(=O)NC1CCC(O)CC1)S(C)(=O)=O +N#Cc1cc2n(n1)CCN(C(=O)CCc1c[nH]c3ccccc13)C2 +COc1ccc(N2CC(C(=O)Oc3ccc(F)cc3)CC2=O)cc1 +COc1cc(C#N)ccc1OCc1cc(=O)n2c(C)cccc2n1 +O=C(c1ccc2c(c1)Cc1ccccc1-2)N1CCCS1(=O)=O +CCc1nn2c(Cc3ccc(F)cc3)nnc2s1 +Cc1cc(C)n(-c2ccc(C(C)NC(=O)C3CCC(=O)N3)cc2)n1 +COC(=O)c1cc(=O)n2c(-c3ccc(OC)cc3)csc2n1 +N#Cc1ccc(NCc2ccc(=O)[nH]c2)cc1Cl +CS(=O)(=O)N1Cc2ccccc2C(c2ccccc2)C1 +C=CC(C)NC(=O)N(C)CCN(C)C(=O)OC(C)(C)C +O=C(CC1C=CCC1)Nc1ccc(C(=O)N2CCCC2)cc1 +COc1ccc(C)cc1C(C)NC(=O)CCNC(=O)C(C)(C)C +O=C(c1cc2ncccn2n1)N1CCCC2(CCCO2)CC1 +O=C(CSc1ncccn1)NCc1cccnc1 +CCN(Cc1cccc(F)c1)C(=O)c1ccccc1C +CC1(CNC(=O)N2CCOCC2C2CC2)COC1 +Cc1ccc(OCC(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)cc1 +COc1cc(C)c(CCCn2cc(N)cn2)cc1OC +Cc1noc(C)c1S(=O)(=O)NCCCSc1ccccc1 +CC(=O)C(C)Cn1nnc(-c2cccc(C(F)(F)F)c2)n1 +Cc1c(Cl)cccc1NC(=O)C(O)c1ccc(F)cc1 +CCc1nc2sc3c(n2n1)CCNC3C(C)(C)C +Cc1ccc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cn1 +Cn1cc(CNc2cccc3c(O)cccc23)cn1 +CNC(=O)COc1cccc(NC(=O)c2ccc(C)n2C)c1 +CCCCNC(=O)CCn1c(=O)[nH]c2ccccc2c1=O +COc1cccc(OCC(=O)NCc2ccoc2)c1 +Cc1nc(Cc2nnc(SCc3ccon3)o2)cs1 +Cc1csc(COC(=O)c2nc(C)oc2-c2ccccc2)n1 +CCc1noc(CSc2nc(C)cc(N)n2)n1 +COc1ccc(C(C)=O)c(OCC(=O)Nc2c(C)cc(C)cc2C)c1 +CC(=O)N(CCc1nc(-c2ccncc2)no1)Cc1ccccc1 +COC(=O)N1CCN(Cc2nnnn2-c2ccc(Cl)cc2)CC1 +Cc1cc(CNC(=O)NC2CCC(O)CC2)ccc1F +Cc1ccoc1C(=O)N(CCO)C1CCCCC1 +CCC(C)Nc1nc(-c2sc(C)nc2C)cs1 +COc1cc(OC)c(C(C#N)NCC(F)(F)F)cc1OC +O=C(CSc1nn2cnnc2s1)c1ccc(Cl)cc1 +CCOc1ccc(-c2nc(CC(=O)OC)cs2)cc1 +N#CCc1cccc(C(=O)NCc2ccc(F)cc2)c1 +O=C(CNc1ccccc1F)Nc1ccc(F)cc1 +Cc1oc2nc(SCC(=O)NCc3cccnc3)nc(N)c2c1C +Cc1oc(-c2ccco2)nc1CC(=O)N1CCCC1Cn1cccn1 +O=C(OC1CCOC1)c1cn(-c2cccc(C(F)(F)F)c2)nn1 +Cc1cccc(CC(=O)N(C(C)C)C2CCOCC2)c1 +Cc1cccc(NC(=O)NCC(=O)N2CCCC(C(=O)N(C)C)C2)c1 +O=C(CSc1nnnn1-c1cccnc1)Nc1ccc(F)cc1 +Cc1ccnc(Nc2ccc(OCc3noc(C4CC4)n3)cc2)n1 +CCOC(=O)N1CC(C)N(C(=O)OCC)CC1C +COCCCOCC(=O)c1ccc2c(c1)OCO2 +CNC(=O)NCC(=O)NCCCOc1ccccc1C +CCCN1CCN(C2CCN(C(=O)c3ccc(CC)cc3)CC2)C1=O +O=C(CCn1cccn1)N1CCCC1c1nnc2n1CCCCC2 +Nc1cc(F)ccc1C(=O)OCC(=O)Nc1ccccc1 +CC(C)c1cc(C(=O)Nc2ccc3c(c2)OCCO3)cs1 +Cc1ccccc1C1CCCN(C(=O)CCc2n[nH]c(N)n2)C1 +CNc1ccc(N(C)S(=O)(=O)c2cccs2)c(C)c1 +COc1ccc(OC)c(C(C)NC(=O)NCC2CC2)c1 +CC(C)c1ccc(Nc2ncccc2C(N)=O)cc1 +COc1ccc(CCC(=O)N2CCC(Nc3cccnc3)C2)cc1 +Cc1cc(C)nc(NC(=O)N(C)C(C)c2ccco2)c1 +COc1ccc(NC(=O)c2cncn2-c2ccccc2)cc1Cl +CC(C)Cc1cc(C(=O)N(C)Cc2cc(-c3ccncc3)no2)on1 +COCCCNc1ncnc(N2CCCCC2C)c1N +Cc1cccc2cc(CO)c(-c3cc(NCCO)nc4[nH]ccc34)nc12 +COc1ccc(Cl)cc1NC1=NS(=O)(=O)c2ccccc21 +Fc1cccc(NCc2nnnn2-c2ccccc2Br)c1 +CCCN(CCc1cccc(F)c1)C(=O)c1ccc(C#N)cc1 +C=CCn1c(SC(C)C(=O)OC)nc2cc(Cl)ccc2c1=O +CCn1c2c(c(=O)[nH]c1=O)C(c1ccc(C)cc1)C1=C(COC1=O)N2 +Cc1occc1C(=O)NCC(=O)N1CCCCCC1c1ccncc1 +CC(=O)Oc1ccc(C(=O)N2c3ccccc3CC2C)cc1 +CC(C)c1ccc(S(=O)(=O)CCC(=O)Nc2ccccc2)cc1 +Nc1cc2[nH]c(=O)c3cc(F)ccc3c2cc1Br +Cc1cnc(N2CCCC(S(=O)(=O)NC3CCCC3)C2)nc1 +CCOCc1ccccc1NC(=O)c1ccc(OC)nn1 +Cc1ccc(-c2n[nH]c(C)c2NC(=O)C(C)C)c(C)c1 +CCCn1ncc(C(=O)N2CCCCC2c2ccn(C)n2)c1C +Cc1ncsc1CN1CCOC2C(Oc3ncccc3F)CCC21 +CCOc1nc(-c2ccc(Cl)cc2Cl)ccc1C(N)=O +CCC(C)N(C)S(=O)(=O)c1ccc(NC)nc1 +CC1CCCCC1NC(=O)CNC(=O)c1ccc(F)cc1 +CCc1ccc(NC(=O)c2onc(-c3ccncc3)c2N)cc1 +CC(NC(=O)c1n[nH]c(=O)[nH]1)c1cccc(Cl)c1 +COC(=O)c1c(C)[nH]c(C(=O)N2CCCCC2C2OCCO2)c1C +Cc1nn(C2CCCCC2)c2[nH]c(C(C)(C)CN3CCOCC3)nc12 +O=C(Cc1n[nH]c(=O)c2ccccc12)NCC(=O)N1CCOCC1 +COc1ccc(-c2nc(NC(=O)c3cc(C)no3)sc2C)cc1 +CCn1ncc(Br)c1C(=O)Nc1cnn(CC2CC2)c1 +CC(NS(=O)(=O)N1CCC(C(C)(C)C)CC1)C1CCC1 +CCCOc1ccc(-c2cc(C#N)c(=O)n(CC)n2)cc1 +Cc1ccc(C(=O)NC2CCCN(Cc3ccccc3)C2=O)c(C)c1 +CC(C)N1CC(C(=O)NCc2cccc(OC(F)(F)F)c2)CC1=O +CC(C)NC(=O)N(C)c1ccc(OCCn2cccn2)cc1 +Cc1ccc(Cl)c2c1CCNC2c1cccnc1C +N#Cc1cccc(COc2ccc(Cl)cc2N)c1 +CC(=O)NC1CC(=O)N(Cc2cccc3ccccc23)C1 +CC(=O)N1CCCc2cc(S(=O)(=O)N=c3cccc(C)[nH]3)ccc21 +CCN(C1CCCCC1)S(=O)(=O)c1cccc(C(=O)N(C)C)c1 +CN1C(=O)C(C)(C)c2cc(S(=O)(=O)NCc3ccccn3)ccc21 +Cc1ccc(NCc2ccc(F)c(Cl)c2F)cn1 +Cn1ccc(NC(=O)NCC(=O)Nc2cc(Cl)ccc2Cl)n1 +CCC(C)Oc1ccc(NC(=O)C2CCCN(C(N)=O)C2)cc1 +CCc1ccc(CNc2cnn(-c3ncccn3)c2)cc1 +N#Cc1cccc(OCC2COC3CN(c4ncccn4)CC23)c1 +COc1ccc2c(c1)NCC(=O)N2CCCC(N)=O +N#CCn1cnc2scc(-c3ccc(F)cc3)c2c1=O +CN(C)S(=O)(=O)N1CCN(c2ncc(C(N)=O)cc2Cl)CC1 +C=CCn1c(SCC(=O)C(C)(C)C)nnc1-c1ccncc1 +O=c1c(Cl)c(Cl)cnn1Cc1nc(-c2cccs2)no1 +COCCOc1ccc(Br)cc1OC +CCNC(=O)CSc1nc(C)cc(C(F)(F)F)c1C#N +Nc1ccc(Cl)cc1NC(=O)CN1CCCCCC1=O +CC(CC#N)N(C)C(=O)Nc1ccc(-c2nc3ccccc3o2)cc1 +Cc1ccc(NC(=O)Cn2nc(C)c3ccccc3c2=O)c(Cl)c1 +COCCCNC(=O)c1cccc2c1CCN2C(=O)c1ccccc1 +Cc1c(N)cccc1NC(=O)CCCOC1CCCC1 +O=C(c1ccncc1)N1CCc2c(ncnc2N2CCOCC2)C1 +CCN1CC(C(=O)NCCc2c(F)cccc2Cl)CC1=O +Cc1ncc(-c2nc3ccccc3o2)c(-c2ccncc2)n1 +CCCn1cccc1C(=O)Nc1ccc(F)c(N)c1 +CSc1ccc(NC(=O)c2cnn(-c3ccncc3)c2C)cc1F +CNC(=O)C(CC(C)C)NC(=O)CCNC(N)=O +CC(Cc1ccsc1)NC(=O)c1ccc(Br)cn1 +CCOc1ccc2c(c1)CN(C(=O)c1c[nH]c(C)cc1=O)CC2 +CC(NC(=O)c1cc(F)cc2[nH]cnc12)c1ccncc1 +Cn1nc(C(=O)N2CCOCC(CO)C2)c2c1CCCC2 +CC(=O)c1ccc(S(=O)(=O)N(C)CCC(C)C)cc1 +COC1CCCCC1OC(=O)c1cnc2onc(C)c2c1 +O=C(NCCOc1ccc(Br)cc1)c1ccc(=O)[nH]c1 +CC1Sc2ccc(C(=O)NCc3ccccc3Cl)cc2NC1=O +N#Cc1c(NCc2cccc(Cn3ccnc3)c2)nc2ccccn12 +COc1ccc(C2CC(=O)Nc3onc(C)c32)cc1Cn1cccn1 +CCCc1ncc(C(=O)NCc2ccc(Cl)cc2)c(N)n1 +CCOc1ccc(CNC(=O)c2cc(-c3ccncc3)cn2C)cc1 +CCOC(=O)C1=C(COC)Nc2ncnn2C1c1ccccc1Cl +COc1cc(F)ccc1N(C)S(=O)(=O)c1cn(C(C)C)cn1 +CCCN(CCC)C(=O)c1ccc(-c2cccs2)nc1N +Cn1ccc(NC(=O)NC(c2ccccc2F)C2CCCC2)n1 +NC(=O)c1ccc(CNc2ccc(F)cc2F)cc1 +Cn1ncc2c1ncn1c(-c3ccccc3Cl)nnc21 +O=C(c1cccc(F)c1)N1CC(c2nc(-c3cccs3)no2)C1 +CN(Cc1cccc(C#N)c1)C(=O)c1sccc1Br +O=C(COc1ccccc1F)Nc1ccc(Cl)cn1 +Cc1csc(NC(=O)CCc2nc3ccccc3[nH]c2=O)n1 +CCOC(=O)CNC(=O)c1ccc(SC)cc1 +CC(c1nc2ccccc2c(=O)[nH]1)N1CCn2c(nn(C)c2=O)C1 +CNC(=O)CC1CC2(CCCC2)Oc2ccc(F)cc21 +Fc1ccc2c(c1Br)C(c1nc[nH]n1)NCC2 +CC(C)CC(NC(=O)C1CCC1)C(=O)N1CCc2nocc2C1 +CCCS(=O)(=O)N1CCCN(C(=O)c2ccccc2Cl)CC1 +CC1CC(C)CN(C(=O)NCC2CN3CCCCC3CO2)C1 +CCC(C)(C)NC(=O)CN1C(=O)C2CCCN2C(=O)c2ccccc21 +CC(=O)N1CCCN(C(=O)CCc2c(C)nc3ncnn3c2C)CC1 +CCc1ccc(NC(=O)CSc2cc(C)[nH]c(=O)n2)cc1 +Cc1noc2nc(C(C)C)cc(C(=O)N3CCCC3C(=O)N(C)C)c12 +CS(=O)(=O)N1CCC(Nc2cccc(F)c2C#N)CC1 +Cc1nnc(SCc2nc3ccccc3c(=O)n2C2CC2)n1C +Cn1c(C(F)(F)F)nn(CCNC(=O)C2CCCC2)c1=O +COc1ncccc1NC(=O)N(C)C(C)c1ccc(C)s1 +CC(CO)NS(=O)(=O)c1ccc2c(c1)CC(=O)N2C +COC(=O)c1c(C)c2c(c(C)c1C(=O)OC)C1CCC2C1 +CCC(C)C(=O)N1CCN(C(=O)CCc2ccc(OC)cc2)CC1 +CCn1c(N)nc2cc(C(=O)NCc3ccc4nonc4c3)cnc21 +CCOC(=O)c1coc(C(=O)Nc2ccccc2F)n1 +CCc1cccc(CC)c1NC1=NS(=O)(=O)c2ccccc21 +Cc1ccc(F)c(CNc2cnn(CC(C)C)c2)c1 +Cc1ccc(NC(=O)COc2cccc(C(=O)N(C)C)c2)cc1 +COC(=O)CN(Cc1ccccc1C)C(=O)c1cc(C)no1 +CCc1cc(N(C)CC(C)(C)O)nc(-c2ccncc2)n1 +COc1cc(C)c(C)cc1S(=O)(=O)Nc1ccccc1O +Cn1ncn(CC(=O)Nc2cccc(Cl)c2)c1=O +CNc1ccc(S(=O)(=O)N(C)c2ccccc2)cc1 +COc1ccc(OC(C)C(=O)NCc2ccccc2CO)cc1 +CS(=O)(=O)c1ccccc1-c1nnc(NC(=O)C2CCCC2)o1 +Cc1n[nH]c(C)c1C(C)C(=O)NC(C)COc1ccc(F)cc1 +COc1cc2c(cc1NC(=O)Cn1cnc(C#N)n1)oc1ccccc12 +O=c1cc(-c2ccccn2)nc(-c2cccnc2)[nH]1 +Cc1ccc(C)c(CC(=O)Nc2ccc(C(N)=O)c(F)c2)c1 +Cc1cccc(NC(=O)C2CCN(C(=O)c3ccco3)CC2)c1C +O=C(Nc1ccc(C(F)(F)F)cc1Cl)NC(CO)c1ccco1 +CCc1cc(C(=O)NC2CC(=O)N(CC)C2)cs1 +COc1ccc(C(=O)NC2CCC(=O)CC2)cc1Br +CCC1COCCN1C(=O)Cc1cccc(F)c1F +Oc1cc(OC(F)(F)F)c2c(c1)C(C1CC=CC1)NCC2 +CC1CC1C(=O)N1CCCC(c2cc3cccnc3[nH]2)C1 +COc1ccccc1C(O)CNc1ccc(F)cc1 +O=C(OCC1CCCCO1)c1cccnc1OCC(F)F +O=C(Nc1ncccc1Cl)C1COc2ccccc2O1 +Cn1c(=O)c2c(ncn2CCc2ccccc2Cl)n(C)c1=O +O=C1CN(c2ccc(NC(=O)c3ccc4ccccc4n3)cn2)CCN1 +CCOc1ccc(S(=O)(=O)N(C)CC(=O)NC(C)(C)C)cc1 +O=C(Nc1ccc(F)cc1)c1cccn(Cc2ccccc2F)c1=O +COc1cccc(NC(=O)NCC(O)c2ccsc2)c1OC +CC(=O)NC1CCN(S(=O)(=O)c2ccc(C)c(Cl)c2)CC1 +COCc1nc(C(=O)N(C)Cc2cccc(C#N)c2)cs1 +COc1ccc(C)cc1-c1nc2sc(C3CC3)nn2c1C#N +NC(=O)C1CCN(C(=O)Nc2ccc(-c3ccccc3)cc2)C1 +Cc1cccc(-c2nnc(SCC(=O)Nc3cc(C)on3)o2)c1 +Cc1ccc(N)cc1NC(=O)CCCn1cccnc1=O +Cn1cc(CC(=O)NCc2ccccn2)c2ccccc21 +COc1ccc(CCC(=O)NCc2nn(C)c3c2CCCC3)cc1 +COc1ccccc1-n1cnc2cc(C(=O)NCc3ccco3)ccc21 +CCOc1ccc(C(=O)NCCc2cc(C)no2)cc1 +CC(C)NC(=O)c1cc(N(C)S(C)(=O)=O)ccc1Cl +Cc1cccc(C)c1OC1CCN(c2ncnc3c2cnn3C)CC1 +CCN(CC)C(=O)Cn1c(=O)cc(C)c2cccc(OC)c21 +CC(C)Sc1ccccc1C(=O)NCCCN1CCCCCC1=O +CC1=C(C(=O)OCC(C)C)C(c2ccccn2)NC(=O)N1C +CCC(C)(C)NC(=O)c1nnn(-c2ccc(F)cc2)c1C +CCC1CN(CC)c2cc(S(N)(=O)=O)ccc2O1 +O=C(NCCc1cccc2ccccc12)c1ccc(-n2ccnc2)cc1 +CCOC(=O)c1cn(-c2ccccc2)nc1-c1ccncc1 +c1ccc(-c2cc(Nc3ncccn3)nc(-c3ccncc3)n2)nc1 +Cc1nn(Cc2ccccc2)c(C)c1C(=O)N1CCC1 +CCC(C)N(C)C(=O)Nc1cccc(NC(C)=O)c1 +NC(=O)Cc1nc(-c2cc3cc(Cl)ccc3o2)cs1 +COc1ccc(C)cc1C(=O)CSc1nnc(-c2ccco2)n1C +Nc1nnc(SCC(=O)Nc2nccs2)n1-c1ccccc1 +Cc1cc(NC(=O)C2(c3cc(-c4ccccc4)on3)CC2)sn1 +Cc1ccc(S(=O)(=O)N(C)Cc2ccc3c(c2)OCCO3)cc1 +CCN(Cc1cccc(C)c1)C(=O)NCC(=O)N1CCCC1 +CCCNc1nc(-c2[nH]c(C)c(C(C)=O)c2C)cs1 +CC(Sc1ccc(C#N)cc1Cl)C(=O)Nc1ncccn1 +N#CCCn1c(-c2ccncc2)nc2cc(F)c(F)cc21 +O=C(NCc1ccco1)N1CCC(n2ccc(C(F)(F)F)n2)CC1 +CC(C)N1CC(C(=O)NCc2ccc(OC(F)F)cc2)CC1=O +COC(=O)c1cc(-c2cccnc2)nc(N2CC(C)CC(C)C2)n1 +Cc1cccc(C)c1OCC(=O)Nc1ccc2c(c1)OCCO2 +CC(C)c1cc(C(=O)NCC(C)c2nc(-c3ccccc3)no2)n[nH]1 +COc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)cc1 +Cc1ccc(NCc2n[nH]c(-c3ccccn3)n2)cc1 +COC(=O)C1(NC(=O)Cc2cccc(OCC#N)c2)CCCCC1 +Nc1ncn(CC(=O)NCCc2ccccc2F)n1 +CCOc1cc(C(=O)N2CCCC(O)C2)ccc1OC +O=C(CC1CCCCC1)Nc1cnn(C2CCOC2)c1 +CC(Cc1ccccc1F)NC(=O)C1CCN(c2cnccn2)CC1 +O=C(Nc1cccc(N2CCCCC2=O)c1)c1cnc2ccccc2n1 +Cc1nn(-c2cc(-c3ccccc3)ncn2)c(C)c1O +Nc1ccc(-c2csc(NC(=O)COc3ccccc3)n2)cc1 +CN(CCc1nccs1)C(=O)NCc1ccnc(OC2CCC2)c1 +COC(=O)c1cc(-c2cc(C)ccc2OC(C)C)[nH]c(=O)n1 +O=c1nc2n(CCOc3cccc(F)c3)cccc-2o1 +CCn1cc(C(=O)Oc2ccc(-n3cccn3)cc2)cn1 +Cc1ncsc1C(=O)NCCOc1cccc(Cl)c1Cl +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1ccc2oc(=O)[nH]c2c1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NC(C)C(C)CO +CCC(C)(C)NC(=O)C(C)Nc1cccc(NC(=O)CO)c1 +C1=C(CN(Cc2cccnc2)CC2CCCO2)COc2ccccc21 +Cc1cc(NC(=O)CCNC(=O)c2ccc(C(C)(C)C)cc2)ccn1 +CCN(Cc1c(F)cccc1F)C(=O)Nc1ccc2c(c1)COC2 +COC(=O)c1ccc(N2CCCC2)c(NC(=O)Cc2ccoc2)c1 +Cn1c(=O)oc2ccc(C(=O)N(Cc3ccccn3)C(C)(C)C)cc21 +CC(C)c1nnc(C23COCC2CN(Cc2nccs2)C3)o1 +Cc1ccc2nc(NC(=O)c3ccccn3)sc2c1 +Cc1cccc2c1C(c1ccc(F)cc1N)NCC2 +Cc1cccc(OCC(=O)Nc2ncccc2C)c1 +Cc1nnc(NC(=O)CCc2c(C)nn3cnnc3c2C)s1 +COc1cccc(-c2cc(C(N)=O)c3cccc(C)c3n2)c1 +CCc1ccc(C(=O)OCC(=O)Nc2ccc(C(N)=O)cc2)cc1 +CC(=O)c1cccc(NC(=O)COc2cc(C)ccc2C(N)=O)c1 +COc1cccc(C(=O)NCC(=O)Nc2ccc3ccn(C)c3c2)c1 +CC(C)CC(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +CN(CC(=O)Nc1cnn(C)c1)c1ccc(Cl)cn1 +Cc1onc(-c2ccccc2Cl)c1C(=O)NCC1(CO)CC1 +COc1cc(Br)c(CC(=O)NC2CC2)cc1OC +CCn1cnnc1CNC(=O)NC(C)c1cccc(Cl)c1 +Cc1ccc(NC(=O)NCc2nnc3ccccn23)cc1C +CCNc1ncccc1COCc1ccccc1Cl +CCN(CCOC)C(=O)C(c1cccc(F)c1)N(C)C +COCC(C)(O)CNS(=O)(=O)c1cc(F)cc(F)c1 +O=C(NCc1cccnc1)c1ccc(-n2cccn2)nn1 +COC(=O)c1ccc(C(=O)Nc2ccnn2CC(C)C)cc1 +O=C(CC1CCCC1)NC1CCC(C(=O)NCc2ccccc2)CC1 +Cc1ccc(CCC(=O)N(CCC(N)=O)c2ccccc2)cc1 +COC(=O)c1cccc2nc(-c3ccc(F)c(F)c3F)nn12 +CC(c1ccccc1F)N(C)C(=O)c1ccn(C)c(=O)c1 +CCC(C)NC(=O)CC(C#N)c1cc(OC)ccc1OC +Cc1ccc(C(=O)OCC(=O)N(CCC#N)c2ccccc2)c(C)c1 +CC(=O)c1ccc(OCCCc2nc(-c3ccc(C#N)cn3)no2)cc1 +CNC(=O)c1cccc(NCC(=O)NCc2ccc(OC)cc2)c1C +O=C(NC1CC2CC1CN2C(=O)c1ccoc1)c1cccs1 +CNc1nc2c(c(=O)n(C)c(=O)n2CCCOC)n1C +CCCn1cc(-c2c(C)c(-c3cnn(C)c3)nc(N)c2C#N)c(C)n1 +Cn1c(=O)c2c(nc(OC3CCC=CO3)n2C)n(C)c1=O +Cc1cc(NC(=O)c2ccco2)ccc1NC(=O)c1cccs1 +Cc1occc1C(=O)OCC1CC(=O)N(C2CC2)C1 +COCCN(C(=O)C(C)OC)c1nc2ccccc2s1 +COc1ccc(NC(=O)c2cnc3ccc(C)cn23)cn1 +CC(C)COCCCNC(=O)C1Cc2ccccc2O1 +CCCN(CCO)C(=O)c1ccc(Cl)c(N)c1 +CCCOc1ncccc1CNC(=O)C1COc2ccc(F)cc2C1 +COc1ccccc1C1(C(=O)OCc2cc3ccccc3[nH]c2=O)CC1 +Cc1n[nH]c(C)c1CCC(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1nc(C(=O)NC(C)c2nc3ccccc3[nH]2)c(C(C)C)s1 +Cc1cc(C(=O)NCC(=O)N(C)Cc2ccc(C(C)C)cc2)c(C)o1 +CCN(CCC#N)C(=O)CNc1cc(F)ccc1C +CNC(=O)CNC(=O)CSc1ccc(Br)cc1C +O=C(NC1CCCC1)C1CCN(c2nnnn2-c2ccccc2)CC1 +N#Cc1cc2c(nc1SCC(=O)NC1CCCC1)CCC2 +CCCC(=O)NCC(=O)Nc1cc(Cl)ccc1Cl +Cc1sc(NC(=O)CSc2ccc(F)cc2)c(C(N)=O)c1C +CCCNc1ccccc1C(=O)Nc1cnn(C)c1 +CC(C)n1ncc(C(=O)Nc2nccs2)c1N +CCC(O)CN1CCN(C(=O)CCn2c(=O)oc3ccccc32)CC1 +CCN(CC)C(=O)CN1CCc2cc(F)ccc2C1 +CC(CC1CCCC1)C(=O)N1CCOC(C)(C)C1 +CCC(C(=O)OC)c1cc(Br)ccc1OC +NC(=O)C1CCN(C(=O)CCCSc2ccc(Cl)cc2)C1 +CCN1C(=O)c2ccccc2C(=O)C2(C)CN(Cc3cccnc3)CC12 +Cc1cccc2c(=O)n(CC(=O)Nc3ccc(C#N)cc3)cnc12 +CCC(C(=O)N1CCc2nc(NC(C)=O)sc2C1)c1ccccc1 +Cc1nc2ncnn2c(C)c1CCC(=O)Nc1ccc(F)c(F)c1 +Cn1c(=O)c2c(nc(N)n2CC(N)=O)n(C)c1=O +Cc1ccc(NC(=O)Cc2nc(Cc3ccc(F)cc3)n[nH]2)cc1F +O=C(NCC(O)CN1CCOCC1)Nc1ccc(F)cc1 +CC(C)C(=O)N1CCC2CN(C)S(=O)(=O)C2CC1 +CCN(CCO)S(=O)(=O)c1cc(Cl)ccc1OC +Cc1ccc(CCNC(=O)Cc2cccc(OCC#N)c2)cn1 +N#Cc1c(F)cccc1N1CCN(c2ccc3nncn3n2)CC1 +CS(=O)(=O)Nc1ccc(Nc2nc3cccnc3s2)cc1 +Cc1c(Cl)cccc1NC(=O)CCCn1cccc1 +CC(C)CCCNC(=O)Nc1ccccc1S(C)(=O)=O +COCCOc1ccc(NC(=O)NC(C)c2nccs2)cc1F +Cc1ccc(C2CC2C(=O)N2CC(C(N)=O)CCC2C)cc1C +CCC(C)c1noc(C2CCN(S(=O)(=O)CC)CC2)n1 +Cc1noc(C)c1CSc1nnc(C2CCCCC2)o1 +CCCOc1ccccc1-n1nnc(C(=O)OC(C)C)c1N +CS(=O)(=O)c1ccccc1NC(=O)c1cc(F)cc(F)c1 +O=C(Cn1ccccc1=O)Nc1cccc(C#Cc2cccs2)c1 +CCn1c(C)ccc(C(=O)N2CCC(C(=O)N3CCCC3)CC2)c1=O +Cc1cc(=O)oc2cc(OCC(=O)N3CC(C)OC(C)C3)ccc12 +Cn1ncnc1-c1ccccc1S(=O)(=O)Cc1ccccc1 +COC(CNC(=O)CSc1ccncc1)c1ccccc1 +CC1(C)CC(=O)c2c(ncc3c2CC(C)(C)CC3=O)C1 +Cc1ccccc1SC1CCN(C(=O)c2ccccn2)CC1 +COc1cc(CNc2ccc(NC(C)=O)cc2)cc(OC)c1O +CCOc1ccccc1-c1nnc2n1CC(C)S2 +COC(=O)c1cc2occc2n1Cc1ccccc1F +Cc1nc(-c2cccc(NC(=O)c3cn(C)nn3)c2)cs1 +Cc1ccc(-c2ccc(=O)n(CC(=O)N3CCOCC3)n2)cc1 +Cc1nc(NCc2nncn2C(C)C)c2c3c(sc2n1)CCCC3 +CC(C)N(Cc1ccc(Cl)c(Cl)c1)S(C)(=O)=O +O=C(CC1C=CCC1)Nc1cccc(Oc2ncccn2)c1 +COC(=O)CNC(=O)C(N)c1c(F)cccc1F +CCc1nc(CC(=O)Nc2c(C)cnn2CC2CC2)cs1 +c1ccc(-c2ccnc3nc(C4CCCCC4)nn23)nc1 +CCN(CC)C(=O)NCc1nnc(C(C)C)n1C +O=c1ccc(-c2ccc(F)cc2)nn1CC(O)COc1ccccc1 +COc1cc(CCC(=O)Nc2nc(-c3ccccn3)cs2)on1 +CC(=O)Nc1ccc(S(=O)(=O)Oc2ccc3c(c2)CCC3)cc1 +O=c1cc(CS(=O)(=O)c2ccccc2)nc(-c2ccncc2)[nH]1 +N#CCCCNC(=O)c1ccccc1C(F)(F)F +Nc1ccccc1NC(=O)CCCN1CCOC1=O +O=C(CSc1cccc2cccc(Cl)c12)N1CCOCC1 +Cc1ccccc1C(C)NC(=O)COc1cccc2c1CCC2=O +CNC(=O)NCC(=O)Nc1cc(Cl)ccc1NCc1ccccc1 +CC(C(=O)NC1CC1)S(=O)c1ccncc1N +CCc1nc(COc2cccc(C(=O)NC)c2)cs1 +Cc1ccc(C2CCCN2S(=O)(=O)N(C)C)cc1C +CCCn1ccc2ccc(NC(=O)NCC(=O)NC)cc21 +Cc1ccc(C(=O)N(C)C)cc1OCc1cnn(-c2ccccc2)n1 +CCn1ncc(-c2c(C)cc(C)cc2OC)c(CO)c1=O +N#Cc1ccc(-c2ccc3c(c2)CCC3)nc1NC1CC1 +N#Cc1ccc(CSc2nnc(-c3cccnc3)o2)cc1 +CC(C)Nc1nnc(-c2scnc2C(C)C)s1 +CCC(NS(=O)(=O)c1cc(C)c(F)cc1Cl)C(=O)OC +CC(C)c1csc(-c2nc(C3CCOC3)no2)n1 +O=C(Nc1ccc(NCc2csc(C3CC3)n2)cn1)C1CC1 +CC(C)N1CC(C(=O)N(C)Cc2cnn(C)c2)CC1=O +CC1CC1C(=O)Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1 +Cc1cc(C)c2sc(NCCN3CCOCC3)nc2c1 +O=C1C2CCN(CC2)C1Cc1ccc2c(c1)OCO2 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(-n2ccnn2)cc1 +N#Cc1ccc(NCc2ccc(Cl)cc2)c(N)c1 +COc1cc(OC)c(C(=O)Nc2nc(C)cs2)cc1OC +O=C(Nc1ncn(Cc2ccc(F)cc2Cl)n1)c1ccccc1F +CC1CCCN(C(=O)Cn2nnc(COc3ccccc3)n2)C1 +COc1ccnc(NC(=O)Cn2cc(C)c3ccccc32)c1 +CCOC(=O)CSc1nnc(-c2ccccc2O)n1C +COC(=O)c1cccc(NC(=O)CNc2ccc(C#N)cc2)c1 +COc1ccc(NC(=O)CC2OC(=O)c3ccccc32)cc1C +O=C(c1ccncc1)c1ccc(NCCC(=O)c2cccs2)cc1 +CC(Sc1nnc(Cc2ccccc2)n1Cc1ccco1)C(N)=O +O=C(Nc1ccc(CCO)cc1)c1ccc2ccccc2n1 +COC(=O)CCCS(=O)(=O)N=c1cc(C)cc[nH]1 +CNC(=O)CN1CCc2nc(NC(=O)c3cccs3)sc2C1 +CN(Cc1c(F)cccc1Cl)C(=O)C1CCCN1S(C)(=O)=O +CN(CCc1ccccn1)S(=O)(=O)c1cc(F)ccc1Cl +C=CCN(CC=C)C(=O)c1ccc(NC(=O)c2scnc2C)cc1 +N#CC1CCN(S(=O)(=O)c2cc(Cl)cc3c2OCC3)CC1 +CCN(CC(=O)NC(C)C)C(=O)CSc1ccccc1Cl +CCC(CNC(=O)CNC(=O)NC)Oc1cccc(F)c1 +COc1cccc(OC)c1C(=O)Nc1cccc(SC)c1 +CCn1nnc2cc(C(=O)Nc3cccc(-c4nnco4)c3)ccc21 +CCOc1nc2ccccc2nc1N1CCC(O)C1 +O=C(NC1(c2nc(C3CC3)no2)CCCCC1)c1ccc[nH]c1=O +O=C(CCNC(=O)C1CCCC1)Nc1ccccc1Cl +CC1COCC(C)N1C(=O)c1ccc(Oc2cccnc2)cc1 +CCOC(=O)C(C#N)(Cc1c[nH]c2ccccc12)NC(C)=O +Cc1oncc1C1NCCc2cccc(Br)c21 +CCC(CO)NC(=O)Nc1cc(-c2nnco2)ccc1C +O=C(NCCNC(=O)c1scnc1C1CC1)c1cccnc1 +CC1CCCC(CNC(=O)c2cc(S(N)(=O)=O)ccc2Cl)C1 +CCC1CCC(NC(=O)CC(NC(C)=O)c2ccccc2)CC1 +O=C(c1ccccc1)N1CCN(c2ccc3nnnn3n2)CC1 +CCC(C)NC(=O)NCc1ccccc1-n1cccn1 +Cc1cc(NC(=O)Cn2ccc(-c3cccc(F)c3)n2)n(C)n1 +COc1ccc(S(=O)(=O)c2c(C)cc(C)[nH]c2=O)cc1 +CCn1cc(CN2CCN(C(=O)c3ccoc3)CC2)ccc1=O +O=C(Nc1ccc(F)cc1)c1cn(-c2ccccc2)nn1 +Cc1ccc2c(c1F)CCNC2c1ccc(CO)cc1 +Cn1cc(CCCNC(=O)NC2Cc3ccccc3C2)cn1 +O=C(Cn1nnc2ccccc21)Nc1cccc2ncccc12 +N#Cc1ccc(CCC(=O)Nc2ccncc2)cc1 +N#Cc1ccc(S(=O)(=O)NC2CCCCNC2=O)cc1 +CN(CC(=O)NC(C)(C)C)C(=O)CSc1nncc2ccccc12 +NS(=O)(=O)c1ccc(NC(=O)Cc2cccc3cccnc23)cc1 +CC(C)(C)c1nc2cc(NC(=O)C3COCCO3)ccc2o1 +NC(=O)c1c[nH]c(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)c1 +CCOC(=O)Nc1cccc(C(=O)NCc2ccccc2)c1 +O=C(COC(=O)c1coc(-c2ccccc2)n1)NC1CCCCC1 +O=S(=O)(NCC1(O)CCCC1)c1ccccc1Cl +CCCc1ccc(S(=O)(=O)N2CCOCC2)cc1 +COCCNC(=O)CNS(=O)(=O)c1cc(Cl)cc(Cl)c1 +CCC(C)C(NC(=O)N1CC(O)=Nc2ccccc21)C(=O)NC1CC1 +Cc1[nH]nc(C(N)=O)c1NC(=O)c1ncn(-c2ccccc2)n1 +O=C(Cc1c[nH]c2ccccc12)NC1CCCNC1=O +CCCn1c(C)nnc1SCCC(=O)Nc1cccc(Cl)c1 +CC(C)n1c(C(F)(F)F)nc2cc(C(=O)N3CCC(O)C3)ccc21 +CN(C)C(=O)c1cccc(CCNc2nc3ccccc3cc2CO)c1 +Cc1noc(C)c1C(C)NC(=O)c1cnn(-c2ccncc2)c1C +Cc1nnc(N(CC(N)=O)CC(C)C)c(C#N)c1C +O=C(CN1CCN(c2ccccc2)CC1)Nc1cccc(F)c1 +COc1ccc(NC(=O)NCCC(C)C)cc1N1CCCC1=O +COCc1nc(-c2cccs2)ncc1Br +NC(=O)C1CCN(C(=O)C2Cc3ccccc3S2)CC1 +CCOCCCNC(=O)Cn1nnc2ccccc2c1=O +COc1ccc(CCc2nccnn2)cc1Br +Cc1nccc(C(=O)N2CCC(C)C3CCCCC32)n1 +COc1cc(C(=O)Cn2cc(N)cn2)cc(OC)c1OC +O=C1CCCN1c1ccc(CNc2nccc(C(F)(F)F)n2)cc1 +COc1ccccc1NC(=O)CCNC(=O)c1ccc2cc[nH]c2n1 +CC(C)c1cc(CNS(=O)(=O)c2c(F)cccc2Cl)on1 +COC(=O)CC1CCCCN1C(=O)CC1C=CCC1 +COC(=O)CC(C)NC(=O)Nc1ccc(F)c(C)c1 +CC1CN(c2nc3sc4c(c3c(=O)n2C)CCCC4)CC(C)O1 +COc1ccc(NC(=O)NCCc2nc(C)cs2)cc1 +CNC(=O)c1c(NC(=O)c2cccs2)sc(C)c1C +O=C(NCCOc1ncccc1Cl)c1c(F)c(F)cc(F)c1F +C=CCn1cnnc1SCC(=O)Nc1c(C)cc(C)cc1C +O=C(Cc1cccc(F)c1F)NCc1ccnc(OCC2CC2)c1 +O=C(CNCCN1CCOCC1)n1c2c(c3ccccc31)CCCC2 +O=C(C1CC1)N1CCc2nc(-c3ccccc3)oc2C1 +CCc1ccc(N2CC(C(=O)OCCOC)CC2=O)cc1 +Cc1cccc(CSc2ccccc2C(N)=O)c1 +CCC(CC)NC(=O)N(C)Cc1ccc(C(=O)NC)cc1 +Cc1ccc(-n2nc(-c3cccs3)cc2N)cc1 +CCc1ccc(CN(C)C(=O)c2cc3ccccc3oc2=O)cc1 +CN(C)c1nc(CN2CCOCC2c2cccn2C)ns1 +CCOC(=O)c1cnc2cc(-c3ccc(Cl)cc3)nn2c1C +CCC(CC)NC(=O)c1ccc(OCc2c(C)noc2C)cc1 +Cc1cnc(NC(=O)CSc2nnnn2-c2ccccc2)s1 +COCCOc1ncccc1NC(=O)Cc1coc2cc(C)ccc12 +Cc1c(C(=O)NCc2nc3ccccc3[nH]2)cnn1-c1ccccc1 +CCOC(=O)c1ccc(OCC(=O)Nc2cc(C)nn2C)cc1 +CC(C)(CNC(=O)CCc1c[nH]c2ccccc12)c1ccncc1 +CN(C)S(=O)(=O)c1ccccc1CNCc1ccncc1 +C#CCN1CCN(C(=O)NC(C)COCC(C)C)CC1 +CC(C)(C)NC(=O)c1cnc2sc3c(n2c1=O)CCCC3 +Cc1ccc(NC(=O)Cc2cccc(OCC#N)c2)cn1 +Cc1nc(CCNC(=O)N(CCC(C)C)C2CC2)cs1 +CCCC1=C(C(=O)OC)C(c2cccnc2)NC(=O)N1C +COC(=O)NCC(=O)N1CCC(c2nc3ccccc3o2)CC1 +c1ccc(-c2csc(Cc3nnc4n3CCCCC4)n2)cc1 +CCOC(=O)CN(C)C(=O)C1CC1c1ccc(C(F)(F)F)cc1 +COc1ccc(NS(=O)(=O)c2cccc(C(C)=O)c2)c(OC)c1 +Cc1sc(=O)n(CC(=O)NCc2ccco2)c1C +CCCc1cc(C(=O)NC(C)c2ccc(C)s2)[nH]n1 +COc1ccc(N2CC(c3nc(-c4ccccc4)no3)CC2=O)cc1 +O=C(c1ccno1)N1CCOC2(COCCN(c3cncnc3)C2)C1 +CN(C)C(=O)N1CCC(C(=O)NC2CCCCc3ccccc32)CC1 +Cc1cccc(-c2nnn3c2COC(CNS(=O)(=O)C2CC2)C3)c1 +Cn1ccnc1C(O)CNc1cccc(C(F)(F)F)n1 +Cc1noc2nc(C3CC3)cc(C(=O)NCc3nnc4n3CCC4)c12 +COc1ccc(CC(=O)NCCc2nc3cccnc3n2C)cc1 +Cc1cccn2c(CNC(=O)c3nnc4n3CCCC4)cnc12 +CC(=O)Nc1ccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)cc1 +CCOc1ccc(C2=CCN(C(=O)CCc3ccncc3)CC2)cc1 +Cc1nc(CNC(=O)Nc2ccc(S(C)=O)cc2)c(C)s1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCNCC1 +FC(F)(F)C1CN(c2cc(N3CCCCC3)ncn2)CCO1 +O=C(Cn1cnccc1=O)Nc1cc(N2CCOCC2)ncn1 +CCCCn1c(N)c(N(CC)C(=O)c2cccc(C)c2)c(=O)[nH]c1=O +Cc1cc(S(=O)(=O)NCc2cc(CC(C)C)no2)ccc1F +O=C(NCc1ccccc1-n1ccnc1)Nc1ccc(F)c(F)c1 +N#CCC(COc1ccc2ncccc2c1)N1CCCC1 +CC(C(=O)NCc1ccco1)n1c(N)nnc1SCC#N +CCN(Cc1ccc(OC)c(OC)c1)C(=O)NCc1ncn(C)n1 +Cc1nn(C)c(C)c1CC(=O)N(C)C(C)Cc1ccc(Cl)cc1 +CCc1noc(-c2cccn2CC(=O)OC(C)C)n1 +O=C(NCc1ccc(-n2cccn2)nc1)N1CCOC2(CCCC2)C1 +Cc1ccc(CNC(=O)NC2CCCC2C(N)=O)c(OCC2CC2)c1 +CC(C)(C)OC(=O)N1CCC(CCOc2ncccc2O)CC1 +O=C1COc2ccc(C(=O)NCCc3cccc(F)c3)cc2N1 +COc1ccc(S(=O)(=O)N(C)c2ccccc2C(N)=O)cc1C +COCc1cccc(C(=O)NCCOc2cccc(F)c2)c1 +O=C1CCC(C(=O)NCCNC(=O)c2ccc(Cl)cc2)N1 +Cc1noc(NC(=O)c2cccc(C(F)(F)F)c2)c1Cl +CC1CCCN(S(=O)(=O)NCC2CN3CCCCC3CO2)C1 +CCc1ccc(O)c(C(=O)N2CCN(C(=O)c3ccoc3C)CC2)c1 +Cc1cc(C)cc(NC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)c1 +CCC(CO)NC(=O)NCc1cccc(OC(F)F)c1 +COC(=O)CN(C)S(=O)(=O)c1cc(Cl)ccc1OC +CC(Oc1ccc(F)cc1Cl)C(=O)NC(C)c1nccs1 +CCC(C(=O)OC)n1c(=O)c(C)nc2ccc(N)cc21 +Oc1ccccc1SCc1nnnn1-c1ccccc1 +Nc1nc(-c2ccccc2)ccc1C(=O)NC1CCCC1 +Cc1nc(C)c(C(C)N(C)C(=O)Cc2ccc(F)c(F)c2)s1 +Cc1nn(-c2ccccc2)c2c1C(c1ccco1)S2 +N#CCCSc1nc(-c2ccc(Cl)cc2)n[nH]1 +Cc1cc(C)c(C(=O)NCc2cn(-c3ccccc3)nn2)c(=O)[nH]1 +COCCOc1nc(C(C)C)nc(NC2CCCC2)c1N +CCCCC(C)NS(=O)(=O)c1ccccc1F +O=C(NCCC1CCCC1)c1ccc2c(c1)CCO2 +C=CCN1C(=O)CC2C1CCN2C(=O)c1cccc(C)n1 +O=C(C1CCCN(c2cnccn2)C1)N1CCCn2ncnc21 +CCOc1ccc2oc(C)c(C(=O)Nn3cnnc3)c2c1 +O=C(c1scc2c1OCO2)N1CCCC(C(=O)N2CCCC2)C1 +COc1ccc(C(O)C(=O)Nc2cccc(OC)c2)cc1 +CCOCCCNc1ncnc2c1cnn2-c1ccc(F)cc1 +C=CCNC(=O)C1(NC(=O)c2cccc(C(N)=O)c2)CCCCC1 +Cc1ccc(CC(=O)Nc2nnc(-c3cc(C)oc3C)o2)c(C)c1 +N#Cc1ccc(N2CCC3(CC2)CC(Nc2ncccn2)CO3)nc1 +CC1CCN(C(=O)C(C)Sc2nnnn2Cc2ccccc2)CC1 +CC(c1ccccc1)N(C(=O)N(C)C)C1CCOC(C)(C)C1 +Cc1cc(NCCCN2CCOCC2)n2c(nc3ccccc32)c1C#N +CCn1cnnc1CNC(=O)N(C)CCOc1cccc(Cl)c1 +CCc1nc(COC(=O)Cc2ccccc2OC)cs1 +CNC(=O)Cc1ccc(NC(=O)NCc2ccc3c(c2)CCC3)cc1 +Cc1c(N)cccc1COc1ccccc1C(N)=O +O=C(Nc1ccc(OC(F)F)cc1)c1ccc(N2CCOCC2)nc1 +CCc1cc(CN(C)C(=O)c2cn3ccsc3n2)on1 +CC(CC(=O)N1CCN(CCO)CC1)c1ccc(C(F)(F)F)cc1 +N#Cc1ccc(Cn2nnn(-c3ccccc3)c2=O)cc1 +COCCCC1CCCN(C(=O)Cn2nc(C)c(C)cc2=O)C1 +N#CC(C(=O)CC1CCCO1)c1nc2ccccc2[nH]1 +CCNC(CCN1CCc2ccccc21)C(=O)OC +O=C(COC(=O)c1ccsc1)Nc1ccc(Br)cc1 +Cc1cccc(CCC(=O)Nc2n[nH]c(-c3ccco3)n2)c1 +O=C(CN1CCOCC1C1CC1)NCc1ccc(F)cc1 +CCC(CC)N(CCO)C(=O)Cc1ccccc1C +CCCCCC(=O)NC(C)c1ccc(S(N)(=O)=O)cc1 +CC(Nc1cccc(OCC(N)=O)c1)c1nc(C(C)(C)C)no1 +C#CCC(OC(=O)c1cnn(C(C)C)c1C)C(C)(C)C +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)N(C(C)C)C1CCC1 +CC(C)(C)n1cc(NC(=O)c2cc(F)ccc2F)cn1 +O=C1CC(Sc2nc3ccccc3s2)C2COC1O2 +COC1CCN(C(=O)C(C(C)C)n2nnc(-c3ccccc3)n2)CC1 +Cc1cc(C)n(-c2ccc(CNC(=O)NC3CCCCC3)cn2)n1 +CCOc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)c(C)c1 +Cc1nc(C)c(CC(=O)OCC(F)(F)F)c(=O)[nH]1 +CCOC(=O)C(C)(C)NC(=O)C1COc2ccc(F)cc2C1 +CCC(C)NC(=O)CCNC(=O)N1CCCC(CO)C1 +CCSc1ccc(NC(=O)CC2C=CCC2)cn1 +CCNC(C#N)CCSc1ccc2c(c1)CCC2 +O=C(CSc1nc(C2CC2)nc2ccccc12)N1CCCCCC1 +CCCCN(C)c1ncnc2cc(OC)c(OC)cc12 +CC(Sc1nnc(-c2ccco2)o1)c1nnc(-c2ccccc2)o1 +Cc1ccc(OC2CCN(C(=O)c3snnc3C)CC2)cn1 +COCCOc1ccc(NC(=O)c2ccncc2F)cc1Cl +O=C(Nc1nc(CCCc2c[nH]c3ccccc23)n[nH]1)c1ccccn1 +Cc1ccc(C)c(CC(=O)N(C)Cc2c(C)nc3sc(C)cn23)c1 +CNC(=O)CCOc1ccc(NC(=O)Cc2cccc(F)c2F)cc1 +Nc1c(NCCc2cccs2)ncnc1Nc1ccccc1 +CN(Cc1cnn(C)c1)S(=O)(=O)c1cccc(Cl)c1 +CN(C)c1nc2sc(C(=O)NCC3COCCO3)cc2s1 +O=c1c2ccccc2cnn1CCOCCOc1ccccc1 +CCOC(=O)CN(C(=O)C1CC(=O)N(C2CCCC2)C1)C1CC1 +COC(=O)C(C)NC(=O)COc1cc(C)ccc1C(C)C +Cn1nccc1C(=O)Nc1nc(-c2ccc(F)cc2)cs1 +COC(=O)c1ccccc1NC(=O)CSc1cn[nH]c(=O)n1 +CN(Cc1ccccc1)C(=O)CC1(Cn2cnnn2)CCCCC1 +COc1ccc(C(=O)c2nccn2C)cc1Cl +COc1cc(C(=O)Nc2ccc(F)cc2)cc(Cl)c1OC +Cc1cccc(NC(=O)c2cc(-c3ccccn3)nc3ccccc23)n1 +Cc1ccc(NC(=O)C2CCCN(C(=O)c3ccc[nH]c3=O)C2)nc1 +COc1ccc(S(N)(=O)=O)cc1C(=O)OC(C)C#N +Cc1ncc(Cl)c(C(=O)N2CCN(C)c3ccccc3C2)n1 +Cc1nc(-c2ncccn2)sc1C(=O)OC1CCCC1 +CCC(=O)Nc1cccc(C(=O)NCCC(=O)OC)c1 +O=c1c2cccnc2ncn1Cc1cccc(-n2cccn2)c1 +CCN(C)c1ccc(C(=O)N(CCC#N)Cc2ccccn2)cc1 +CCC1CCC(CNC(=O)c2c(C)nn(C)c2C)CC1 +COc1cccc(C(=O)NCCCN(C)c2ccccc2)c1 +O=c1cc(-c2cccnc2)nc(C2CCCN(Cc3ccccn3)C2)[nH]1 +COc1ccc(-n2ncc(C#N)c2C(F)(F)F)cc1 +Cc1cc2nnc(SCCCc3cnn(C)c3)n2c(C)n1 +COc1ccc(COC(=O)c2cnc3ccc(C)cn23)cc1OC +COc1ccc(-c2cccc(O)c2)n2nc(N)nc12 +CCCn1cc(N)cc1C(=O)Nc1ccc(C)cc1 +COc1ccc(F)c(NCc2noc(C(C)C)n2)c1 +O=C(Nc1cccc(C(=O)N2CCCCC2)c1)N1CCC(CO)CC1 +Cc1nc(NCCNC(=O)Nc2ccc(F)cc2)cc(N(C)C)n1 +O=C(NC(C1CC1)C1CC1)Nn1cnc2ccccc21 +O=C(NCc1ccc(-c2nc3ccccc3[nH]2)cc1)c1cccc(F)n1 +O=C(Nc1ccc2nc[nH]c(=O)c2c1)c1ccco1 +FC(F)(F)c1ccc(NCCCN2CCOCC2)nc1 +CC(C)N(Cc1ccccc1)C(=O)Cn1nnc(-c2cccs2)n1 +c1ccc(-n2ccc(CN3CCOC(c4nccs4)C3)n2)cc1 +CCNC(=O)C1CCCN(C(=O)Cc2ccc(F)c(F)c2)C1 +N#Cc1ccccc1CSc1ccc2c(c1)OCCCO2 +O=C1NCCN(C(=O)C2CCOC2)C1c1ccccc1Cl +CC(C)C(C(=O)N=c1[nH]c2ccccc2[nH]1)N1CCCC1=O +CSc1nsc(SC)c1NC(=O)OCC(F)(F)F +CNc1cncc(C2CCCN2c2ncccn2)n1 +NC(C(=O)NCCO)c1ccc(F)c(Cl)c1F +FC(F)(F)c1nc(SCCn2cncn2)c2ccccc2n1 +Cn1nccc1C1CCN(c2c(C#N)c(=O)n(C)c(=O)n2C)CC1 +CNC(=O)c1cccc(NC(=O)c2cc(C)n(C3CC3)c2C)c1C +O=C(Cn1c(-c2cscn2)nc2ccccc21)NCc1ccncc1 +COc1ccccc1CNC(=O)Cn1nc(C)nc1C +CC(C)c1noc(OCC(=O)Nc2ccccc2)n1 +COC(=O)c1ccccc1NCC(O)c1cc(F)ccc1F +COC(=O)c1c(-c2cccc(F)c2)noc1N1CCOCC1 +Cc1ccc2nc(NC(=O)c3cncn3-c3ccccc3)sc2c1 +O=C1OCCC1N1CCN(C(=O)C2COc3ccccc3O2)CC1 +COc1ccc(S(=O)(=O)N(C)CC(=O)NCC2CCC2)cc1 +Nc1ccccc1-c1nnn(CC(=O)Nc2ccc(Cl)cc2)n1 +CCCCS(=O)(=O)N1CCCC(c2nnc(C(F)(F)F)o2)C1 +COc1ccc(NC(=O)CCn2cccn2)c(OC)c1 +CCN(CC(=O)Nc1ccccc1OC)c1cc(C)nc2ncnn12 +O=C(C1CC1)N1CCN(S(=O)(=O)c2ccccc2)CC1 +COc1cccc(C(=O)CSc2nnc(-c3ccoc3C)n2C)c1 +CCNC(=O)c1ccc(OCc2ccc(C)cc2)c(N)c1 +COCCC1(CNC(=O)c2scnc2C2CC2)CC1 +CC(=O)C1(c2ccccc2)CCN(S(=O)(=O)c2ccsc2)CC1 +COC(=O)c1ccc(C(=O)Nc2ccc(Cl)cc2F)cn1 +O=C(NCc1ccc(N2CCCCC2=O)cc1)c1ccc2cc[nH]c2c1 +Cc1ccccc1SCC(=O)NCc1ccco1 +O=C(Nc1ccc(SCC(=O)N2CCCC2)nn1)C1CC1 +CCOC(=O)c1cnc2c(ccc3ncccc32)c1Cl +CCOC(=O)c1ccccc1C1=NCCc2cc(OC)c(OC)cc21 +CCOC(=O)n1c(SCC(=O)N(C)C)nc2ccccc21 +CC(C)(C#N)N1CCN(C(=O)c2cccs2)CC1 +CC(C)(C)C(=O)N1CCC(C(=O)NCCNC(=O)c2ccco2)CC1 +O=c1ccc(-c2ccccc2)nn1CC(O)c1ccc(Cl)cc1 +Cc1nnc2ccc(N3CCC4(CCCCC4)C3)nn12 +Nc1nnc(SCC(=O)NC2CCCCC2)n1-c1ccccc1 +O=C(COc1ccc2ccc(=O)oc2c1)N=c1[nH]c2ccccc2[nH]1 +O=C(Cc1nc2ncccn2n1)NCC1CCCCO1 +CCc1nc(C)c2c(C)c(C(=O)N(C)C)sc2n1 +Nc1nc(-c2cccs2)ncc1C(=O)N1CCOCC1 +CS(=O)(=O)c1cccc(C(=O)Nc2cccc(Cl)c2F)c1 +O=C(NCc1cccnc1)C1CC2CN(Cc3ccncc3)CC1O2 +CSc1nc(-c2ccco2)nc(C)c1C(=O)NC(C)CO +CC(NC(=O)c1ccc2c(c1)NC(=O)CCS2)c1ccc(F)cc1 +O=C(Nc1c(F)cccc1F)C1CCCN1C(=O)c1ccccc1F +COCC(C)NC(=O)N1CCN(Cc2cccc3ccccc23)CC1 +Cc1cc(-c2cc(-c3cccc(O)c3)c(C#N)c(N)n2)c(C)s1 +CCS(=O)(=O)N(C)C(C)c1cc(F)ccc1F +CC1CCCC(C)N1S(=O)(=O)c1cccc(C#N)c1 +Cc1cccc(C(=O)NCCC(=O)Nc2nnc(C(C)(C)C)s2)c1 +CC1CCCC(NS(=O)(=O)N2CC(C)CC(C)C2)C1 +O=C(CSc1ccc2c(c1)CCC2)N1CCC2(CC1)OCCO2 +CCN(C(=O)c1ccc(=O)n(C)c1)C(C)c1ccc(F)cc1 +O=C(NCc1ccnc2ccccc12)C1CCOc2ccccc21 +Cc1ccc(-c2nnn(CC(=O)NCCC(C)C)n2)cc1 +O=C(c1ccccc1)N1CCC2(CC1)NCC(=O)N2Cc1ccccc1 +Cc1cc(Cl)ccc1OC(=O)Cn1c(=O)cnc2ccccc21 +Cc1nc2ccc(NC(=O)c3ccc(-n4cccn4)cc3)cc2s1 +Cc1nc(C(C)N(C)C(=O)c2cnc3sccn3c2=O)c(C)s1 +CC(C)c1cc(C(=O)NC2CCOc3ccccc32)n[nH]1 +COc1ccc2[nH]cc(CC(=O)Nc3ccc(F)c(C#N)c3)c2c1 +COc1c(C)cc(-c2nc(C)nc(C)c2N)c(C)c1C +CCOC(=O)c1ccsc1NC(=O)c1ccnn1C +c1cnn(CCSc2nnc3n2CCCCC3)c1 +CCc1ccc(CNC(=O)COC(=O)c2ccc3c(c2)OCO3)cc1 +CC(=O)Nc1ccc(Cl)cc1-c1cccc(C(C)=O)c1 +CC(C)(C)C(=O)NCCC(=O)N1CCc2sccc2C1 +Cc1nc(C)n(CC2CN(Cc3ccc4c(c3)OCCO4)CCO2)n1 +COCCNC(=O)Nc1ccccc1C(=O)N(C)C1CCCCC1 +Nc1occ(-c2cccc(F)c2)c1C(=O)c1cccnc1 +CSc1cccc(NC(=O)c2cc(C)n(C3CC3)c2C)c1 +COC(=O)c1cnc2nc(-c3cccnc3)nn2c1N +CCOc1cc(N2CCCC(O)C2)nc(SC)n1 +CSc1ccc(C(=O)NCc2nncn2-c2ccccc2)cc1 +CN(Cc1ccsc1)C(=O)c1n[nH]c(N)c1-c1ccccc1 +O=C(NCCNS(=O)(=O)c1cccc(Br)c1)C1CC1 +CC(=O)Nc1ccc(S(=O)(=O)NC(C)c2ccccc2C)cc1 +CN(Cc1ccncc1)C(=O)NCCNS(=O)(=O)c1ccccc1 +NC(=O)Nc1ccc(C(=O)NCC2CC=CCC2)cc1 +Cc1csc(N2CCN(CC(=O)Nc3c(C)nn(C)c3C)CC2)n1 +COc1ccc(CNC(=O)Nc2ccc(F)cc2OCC2CC2)cn1 +Cc1ccc(Sc2ncccc2C(=O)N2CCCC(O)C2)c(C)c1 +O=C(NCCSc1ccccc1)NCCc1ccccn1 +Cc1ccc(CCNC(=O)N2CCN(Cc3ccon3)CC2)cn1 +CCOC(C)c1noc(CN2CCOCC2C2CCCCC2=O)n1 +c1ccc(N2CCOCC2)c(CN2CCCC(c3nccs3)C2)c1 +Cc1nc(Cc2cccc(Br)c2)nc(C)c1N +Cc1cc(C)c(OCC(=O)Nc2ccccn2)c(Cl)c1 +Fc1ccccc1N1CCC(CNc2nccc(-c3ccncc3)n2)C1 +COc1cccc(F)c1C(=O)N1CCC(C(O)CC(C)C)CC1 +Nc1c(NCCC2=CCCCC2)ncnc1NCc1ccccc1 +O=C(C(O)c1ccccc1Cl)N1CC2C3CCC(C3)C2C1 +CC(=O)Nc1ccc(Cl)c(NC(=O)N2CCCC(O)C2)c1 +Cn1cccc1C(=O)Nc1ccc(OC(F)F)cc1OC(F)F +Cc1cccc2c(=O)n(CC(=O)NCCC(C)C)cnc12 +Cn1nc(-c2ccncc2)nc2c(=O)n(C)c(=O)nc1-2 +CC(NC(=O)CCC1CCCO1)c1ccc(F)c(Cl)c1 +Cc1n[nH]c(C)c1NC(=O)COc1ccc(CCO)cc1 +COCC(C)Nc1ncnc(Nc2ccc(F)c(F)c2)c1N +CC(C)n1ncc(S(=O)(=O)NCc2ccccn2)c1N +CCC(=O)N1CCN(CCNS(=O)(=O)CC)CC1 +CN(C)S(=O)(=O)c1cccc(CSc2nccn2C)c1 +Cc1ccccc1C(=O)NCC(=O)NCC1CN2CCCCC2CO1 +CCOC(=O)C1CCN(C(=O)Nc2ccccc2OC)CC1 +CN(C(=O)CSc1nc2ccccc2[nH]1)C1(C#N)CCCCC1 +O=C1CCCCC1Sc1nnc(Cc2cccs2)n1C1CC1 +O=C(c1cccc(F)c1)N1CC(c2nc3ccccc3[nH]2)C1 +CN(C)c1nc(N)nc(COC(=O)c2ccc(NC(N)=O)cc2)n1 +O=C(CCn1c(=O)oc2ccccc21)NCc1ccc(Cl)cc1 +O=C(CCNS(=O)(=O)c1ccc(F)cc1)NCc1ccco1 +CCc1noc(C2CC(=O)N(c3ccc(C)c(C)c3)C2)n1 +CC(C)c1ccc(S(=O)(=O)NCc2ccco2)cc1 +Cc1sc2ncnc(SCCC(N)=O)c2c1C +COc1ccccc1OCCNC(=O)c1ccc2c(n1)NC(=O)CC2 +O=C(Cc1cccs1)Nc1ccc(N2CCNC2=O)cc1 +CCC(=O)Nc1ccc(C(=O)Cn2nnc(-c3ccccc3)n2)cc1 +O=C(Nc1ccccc1-n1ccnc1)c1cnc(-c2ccccc2)s1 +COc1ccc(-c2nc3cc(NC(C)=O)ccc3[nH]2)cc1 +O=C(NCCc1ccccc1)C(O)c1ccc(F)cc1 +CN(C)C(=O)CCCC(=O)Nc1ccnn1Cc1ccc(Cl)cc1 +Cc1cccc(NC(=O)c2onc(-c3ccccn3)c2N)c1 +CCNc1ccc(S(=O)(=O)N(C)CCC#N)cn1 +Cc1nc(N2CCOCC2)ncc1C(=O)NCCC(C)C +COCCN(CCOC)C(=O)c1cc2c(C)cc(C)c(C)c2[nH]1 +COc1ccc(OC)c(NC(=O)NC(CCO)c2ccccc2)c1 +CCCS(=O)(=O)N1CCC(NC(=O)Nc2ccccn2)CC1 +NC(=O)c1n[nH]c2ccc(NCc3csc(C4CC4)n3)cc12 +CCNC(=O)CNC(=O)c1cc(Br)ccc1Cl +CCc1ccc(NC(C)C(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +CCC(CO)NC(=O)NCC(C)(C)c1ccccc1 +CC(=O)c1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)cc1 +Cc1ccc(CCNC(=O)NCC(C)(C)c2ccncc2)cc1 +CC1CCCC(C)N1C(=O)CN1CCN(c2ccccc2O)CC1 +COc1ccc2c(c1)CCNC2COc1ccccc1 +CCC(=O)Nc1ccc2c(c1)C(=O)N(CC)c1ccccc1O2 +CN1C(=O)C(O)(CC(=O)c2ccccn2)c2cc(Cl)ccc21 +Cc1ccc2c(=O)cc(C(=O)Nc3cccc4cccnc34)oc2c1 +CC(C)C(O)C1NCCc2cc(Cl)cc(F)c21 +CN(CCc1ccccc1)S(=O)(=O)c1ccc(F)cc1 +Cc1cc2ccccc2n1CCc1nc(C2CCOC2)no1 +NC1=NC(=O)C(Cc2ccc(F)cc2)(c2ccc(Cl)cc2)N1 +Cc1nnc(NC(=O)CSc2nncn2C(C)C)s1 +CCc1nc2n(n1)CCCC2NC(=O)N(C)CC1CCCC1 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1c(F)cccc1F +COCCOc1cc(NCc2ccc(C)cc2)ncn1 +CCC(CC)C(=O)NCC(C)(C)N1CCOCC1 +COC(=O)Cn1cc(NC(=O)c2ccoc2C)cn1 +COc1cccn(CCOc2cccc(N)c2)c1=O +Cc1ccc(C(=O)NC2CCN(C(=O)c3cnccn3)CC2)cc1C +CNc1c(NC(=O)c2ccccc2Cl)c(=O)oc2ccccc12 +Cc1c(C(=O)N2CCOCC2)[nH]c2c1C(=O)CC(C)(C)C2 +COc1ccc(S(=O)(=O)N(C)Cc2sccc2C)c(OC)c1 +CC1NCc2ccccc2C1NC(=O)c1ccccc1Cl +CCC(NC(=O)c1cccc(-c2ccoc2)c1)c1c(C)noc1C +COC(=O)c1ccccc1CN(C)C(=O)Cc1cccc2cccnc12 +O=C1CCN(C(=O)Nc2cccc3ccccc23)CCN1 +CC1CN(C(=O)c2ccc(=O)n(C)n2)CCC1(O)C1CCOCC1 +CC(C)n1ccc2c(NC(=O)CNC(=O)c3cccnc3)cccc21 +CCn1cc(C(=O)N2CCCC2)c2nn(-c3ccccc3)c(=O)c-2c1 +CC(C)N1CC(C(=O)N(C)c2cccc3ncccc23)CC1=O +CC(C)CC(=O)C(N)Cc1cccc(Br)c1 +CC(C)(C(=O)NC1CCN(S(C)(=O)=O)CC1)c1ccccc1F +O=C(NCc1ccco1)N(CCCO)C1CCCc2ccccc21 +C=CCCC(=O)N1CCN(CC(O)C(C)(C)C)CC1 +COc1cccc(-c2noc(-c3cnc4ccccn4c3=O)n2)c1 +COc1cc(C(C)=O)ccc1OCc1nnc(-c2cccs2)o1 +CC(=O)NCCCCCC(=O)N1CC(C)c2ccccc21 +CCN(Cc1ccccc1)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +C#CCNC(=O)CN1CCN(C(=O)C(C)(C)C)CC1 +COc1ccnc(N2CCN(Cc3nnnn3C3CC3)CC2)n1 +O=C(c1ccc(-n2cnnn2)cc1)N1CCCc2cc(F)c(F)cc21 +O=C(Cc1cccs1)NCc1ccc(N2CCCCC2=O)cc1 +CCSc1nnc(NC(=O)c2csc3c2CCCC3)s1 +CCc1cc(N)cc(C)c1NC(=O)c1cccc(OC)c1 +Cc1ccn2c(=NC(=O)COc3ccc(Cl)cc3)[nH]nc2c1 +NC(=O)CN(Cc1ccc(-n2cncn2)c(F)c1)Cc1cccs1 +Cc1ccc(Cl)cc1NC(=O)COc1cccc(C(C)O)c1 +Cc1n[nH]c(C)c1NC(=O)CSc1nnnn1-c1cccc(F)c1 +COc1ccccc1C(=O)NC1CCN(C(=O)CC(C)C)CC1 +Cn1c(CCn2ccnc2-c2ccc(-c3cc[nH]n3)o2)n[nH]c1=O +O=C(NCc1ncc(-c2ccccc2)[nH]1)c1cn(-c2ccccc2)nn1 +N#Cc1ccc(Oc2cccc(NC(=O)C3CC4CCC3O4)c2)cc1 +COC(=O)CC(C)C(=O)NCC1(c2ccc(F)cc2F)CC1 +CCN(CCC#N)S(=O)(=O)c1ccc(F)cc1Cl +CC(=O)N1CCN(C(=O)C(C)N(C)c2ccc3ccccc3c2)CC1 +O=C(Cc1coc2cc3c(cc12)CCC3)NCCN1CCOCC1 +Cc1nc(C(NC(=O)CC(F)(F)F)c2ccc(Cl)cc2)no1 +Cc1nc(CNC(=O)COc2ccc(C(C)C)cc2)cs1 +COC(=O)c1ccc(NC(=O)c2cc3ccccn3n2)cc1 +Nc1ccc2c(-c3cnn(-c4ccccc4)c3)n[nH]c2c1 +COc1ccccc1NC(=O)c1ccc(N)cc1Cl +O=C1CNc2ncnc(NCCn3cccn3)c2N1 +Cc1nc(C)c(CC(=O)Nc2cccc(-c3ccsc3)c2)c(=O)[nH]1 +CCNC(=O)C1CCN(C(=O)CNC(=O)c2cccc(F)c2)CC1 +NC(=O)c1cccc(CC2CCN(C(=O)c3cc(C4CC4)n[nH]3)C2)c1 +COC(=O)N1CCN(S(=O)(=O)N(C)CCC#N)CC1 +CCCC(C)C(=O)NCc1cccc(NC(=O)c2ccco2)c1 +CCCCN(C)C(=O)c1ccc(-c2cccs2)[nH]c1=O +Cc1cc(C2CCCN2C(=O)c2cc(C)n(C(C)C)c2C)on1 +CC(=O)Nc1ccccc1C(=O)N1CCCCC1C +C=CCNc1nnc(SCC(O)c2ccccc2)s1 +O=C(CCCNC(=O)c1ccco1)NCC1CCCCC1 +Cc1ccc(CNC(=O)c2csc(-c3cnccn3)n2)cc1 +CC(C)Cc1nc(CS(=O)(=O)c2ccccc2Cl)no1 +O=C(CN1CCCCC1=O)Nc1nc(C(F)(F)F)cs1 +Cc1ccccc1Cc1nnn(Cc2nnnn2C2CC2)n1 +O=C(NCc1ccc2c(c1)OCCCO2)C1CC2CCC1O2 +CC(C)(C)S(=O)(=O)c1ccc(NCC2CCCC2O)cn1 +CCOc1cc(S(=O)(=O)Nc2cccc(C)n2)c(C)cc1C +COC(=O)CC1CCCCN1C(=O)c1cccc(C)n1 +CC(C)NC(=O)N(C)c1ccc(OCC(=O)NCc2ccco2)cc1 +O=C1CCCN1CCCNC(=O)N1CCC(O)CC1 +COC1CCCC1OC(=O)c1c(C)c2ccccc2oc1=O +COc1ccccc1C(NC(=O)c1cccnc1)c1noc(C)n1 +CCc1cccc(C)c1NC(=O)COc1ccc(OC)cc1 +COCCCOC(=O)c1cnn(-c2ccc(Br)cc2)c1 +CNC(=O)c1cc(NC(=O)CC2CCCC2)ccc1Cl +O=C1COc2ccc(C(=O)Nc3ccccn3)cc2N1 +Cc1cnn(CC(C)NCC2=NS(=O)(=O)c3ccccc3N2)c1 +Cc1onc(-c2ccccc2Cl)c1C(=O)Nc1ccc(O)cc1 +Cc1nc(-c2cccs2)c(CC(=O)NCc2ccccc2F)s1 +Cc1n[nH]c(C)c1CCOC(=O)CN1C(=O)CSc2ccccc21 +CN(C(=O)c1snc(C#N)c1N)C1CCCCC1 +O=C(NC1CC1)c1ccnc(N2CCC3(CCCO3)CC2)c1 +Cc1cc(C(=O)N2CCCC2c2ccccc2C)c2c(C)noc2n1 +Cc1nn(CC(=O)N2CCC(NS(C)(=O)=O)CC2)c(C)c1Cl +O=C(NCCCO)c1cccc(Br)c1 +CC(Sc1nnc(-c2ccco2)n1N)c1ccccc1 +CC(NC(=O)COc1ccc(F)cc1)c1ccc(F)cc1F +COc1ccc(OC)c(-n2ccnc2-c2cnc(C(C)C)nc2)c1 +CCCNC(=O)c1cccc(S(=O)(=O)N(C)c2ccc(C)cc2)c1 +COC(C)(C)CC(C)NC(=O)NC1CCCCC1O +Cc1ccc(-n2nnnc2CNC(=O)CCc2ccccc2)cc1C +CCNC(=O)c1ccc(NC(=O)c2cccc(C#N)c2)c(C)c1 +CCC(=O)c1cccc(S(=O)(=O)NC2CCCCC2O)c1 +COC(=O)Cn1cc(NC(=O)c2ccc(C)n2C)cn1 +CCOC(=O)CN(C)C(=O)C1CCCN(C(N)=O)C1 +O=C(Nc1ccccc1Cl)N1CCn2nncc2C1 +COC(=O)Cc1cnnn1CCOc1ccc(N)c(C)c1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)NC(C)C1CC1 +O=C(COc1ccc2nc3n(c(=O)c2c1)CCC3)Nc1ccccc1 +Cc1ccc(CC(=O)NCc2ccc(Br)cc2F)cn1 +Cc1cc(C(=O)N2CCCC(c3noc(C(C)C)n3)C2)no1 +COc1ccc(F)c(C(=O)N2CCC(C)(O)C(C)(C)C2)c1F +CC(NC(=O)c1ccoc1)C(=O)Nc1ccc(Nc2ccccc2)cc1 +O=C(NCc1nnc2ccccn12)Nc1ccnn1C1CCCCC1 +O=C(Nc1ccc2[nH]ccc2c1)N1CCc2cc(F)ccc2C1 +CC(C)Cc1nc(NC(=O)c2ccn3nnnc3c2)n[nH]1 +CC(C)C(=O)N1CCOCC2(CCC(Cn3ncccc3=O)O2)C1 +c1ccc(-c2cnc(CSc3nnnn3C3CC3)o2)cc1 +O=C(NCCCc1nc(-c2ccncc2)cs1)C1CC2CCC1O2 +CCN(C(=O)CSc1ccncc1)C1CCCCC1 +O=C(NCCCOCc1ccccc1)Nc1ccccc1F +CCN(CC)C(=O)c1ccc(NC(=O)C2CCOCC2)cc1 +Cc1cc(NCCS(N)(=O)=O)n2ncnc2n1 +CCC(CO)NS(=O)(=O)c1ccc(Br)cc1 +CCc1cc(NCCc2nc3ccccc3[nH]2)n2nccc2n1 +CC(=O)NCC(CO)Cc1ccc(C(C)(C)C)cc1 +COC(=O)c1c(O)ccc(-c2ccc(NC(C)=O)cc2)c1C(=O)OC +Cc1sc(-c2ccco2)nc1C(=O)OCC1CCC(=O)N1 +CC(=O)N1CCCN(Cc2ccccc2)c2ccccc21 +CN(Cc1ccoc1)C(=O)c1sccc1Br +Cc1ccc2c(c1)SC(C(=O)NCCc1nnc3ccccn13)C2 +CC1Oc2cc(N)ccc2N=C1Nc1ccc(Cl)cc1 +CN1CC2(CCN(C(=O)c3cccc(-c4ccco4)c3)CC2)CC1=O +Nc1c(N2CCc3ccccc32)ncnc1-n1cnc2ccccc21 +CC1C(OC(=O)CCCCNC(N)=O)CC2CC1C2(C)C +CCCC(=O)NC1CCCN(C(=O)c2scnc2C2CC2)C1 +Cc1ccc(NC(=O)N2CCC(NC(=O)c3ccccc3)CC2)cc1 +Cc1ccc(OCCCNC(=O)Cc2nc3ncccn3n2)cc1 +COc1ccc(-c2csc(NC(=O)c3ccncc3)n2)cc1Cl +Cc1cc(NC(=O)C(C)c2c(C)noc2C)c2ncccc2c1 +Cc1cc(CN(C)C(=O)CCc2c[nH]c3ccccc23)n[nH]1 +CC(NC(=O)c1ccccc1)C(=O)NC1CCCc2ccccc21 +CCOC1CC(NC(=O)Nc2c(C)noc2CC)C12CCC2 +COc1ccc(C(=O)Nc2ccc(N(C)C)nc2)cn1 +CCN(CCC#N)C(=O)CNc1c(C)cc(C)cc1C +O=C(NCCNc1nc2ccccc2s1)c1cc[nH]n1 +CN(C)c1ccc(C(=O)N(Cc2c(F)cccc2Cl)C2CC2)cn1 +C=CCCCN(C)C(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +Cn1cnnc1SCCNC(=O)C1CC(=O)N(C2CCCC2)C1 +COc1cccc(CC2CN(Cc3ccc4c(c3)CCO4)CCO2)c1 +CC1(CNC(=O)Nc2cccc(S(=O)(=O)C(F)F)c2)CCCC1 +Cc1nc(NC(C)(C)CO)c2c(-c3ccc(F)cc3)csc2n1 +Brc1cccc(-c2ccnc3ccnn23)c1 +C#CCN1CCN(S(=O)(=O)c2cc(F)ccc2F)CC1 +CNS(=O)(=O)c1cc(C(=O)N2CCOCC2C2CC2)co1 +COc1cccc(CC(=O)N(Cc2cccs2)CC2CCCO2)c1 +CCOCC(=O)NCc1cc(Br)ccc1OC(F)F +N#CC(N)(COCC1CCOCC1)c1ccccc1 +O=C(NCCN1CCc2ccccc2C1)C1CC=CCC1 +CC(NCC1(c2c(F)cccc2F)CC1)c1cnn(C)c1 +COc1ccc(CCNC(=O)c2cc3ccoc3s2)cc1 +CCCOC1CCCN(C(=O)C2CC(=O)N(C3CC3)C2)CC1 +Cc1cc(C)nc(Nc2nc(-c3ccccc3C)n[nH]2)n1 +O=C(NCc1ccccc1-n1ccnc1)c1cc(-c2ccco2)[nH]n1 +CN(C)c1ccc(C(=O)NCc2ccsc2)cc1N +CCCCNC(=O)Cn1c(C)cc2nc3sc(C)nn3c(=O)c21 +CC(C)(C)N1CCN(C(=O)C2CC(=O)N(c3ccc(F)cc3)C2)CC1 +CCC(C)NC(=O)Cn1nc(C(=O)Nc2ccccc2)ccc1=O +O=C1COc2cc(O)ccc2N1CCCc1ccccc1 +N#Cc1cnc(-c2ccc3c(c2)CCCO3)cc1Cl +CCN(Cc1nnc(C(C)(C)C)o1)c1ccccc1C +Cc1cc(N)nc(COc2cccc(Cl)c2Cl)n1 +Cc1ccc(C(=O)N2CCN(c3ccnc(-c4ccccc4)n3)CC2)o1 +CC(C)c1ccn(-c2ccc(N)c3ncccc23)n1 +Cc1ccc(C(=O)COC(=O)c2ccc(S(C)(=O)=O)cc2)s1 +CCOc1cccc(-c2c(C)cn(CC)c(=O)c2C#N)c1 +O=C(NCCO)c1nc(COc2ccc3c(c2)OCO3)no1 +FC(F)(F)c1cccc(Cl)c1NCc1ccncc1 +CCc1nc2c(sc3ncccc32)c(=O)n1CC(=O)NC(C)C +Nc1ccc(-c2cnc(CN3CCOCC3)o2)cc1 +COc1ncc(-c2nccc3occc23)c(OC)n1 +COC(=O)c1ccccc1S(=O)(=O)N(C)C(C)C(C)(C)C +N#CCCCn1cnc2c(F)cc(Br)cc2c1=O +CCn1nc(C)cc1C(=O)NCC(=O)Nc1ccc(C(=O)OC)cc1 +Cc1cc2c(SCCC(=O)Nc3ccccc3F)ncnc2s1 +COc1cc(-c2ncc3ccccn23)cc(OC)c1OC +CC(C)(CNC(=O)Nc1ccc(F)cc1F)NS(C)(=O)=O +CCc1nnc(CN2CCN(c3ncnc4sccc34)CC2)o1 +O=C(N1CCCC1)C(O)(c1ccccc1)c1ccccc1 +CCCc1nnc(C(=O)N(C)Cc2cccc3cnccc23)o1 +NS(=O)(=O)N1CCN(C(=O)C2CCCC2)CC1 +O=C(C1CCC(Cn2cnnn2)CC1)N1CCc2ccccc2C1 +Cc1nc(Nc2cccc3cccnc23)ccc1N +COC(=O)c1cc(CSc2ccccn2)oc1C +N#Cc1ccc(CN2CCc3cc(S(N)(=O)=O)ccc32)cc1 +CCC1CNc2cc(C(=O)C(C)NCc3ccncc3)ccc2O1 +CC1COC(c2ccccc2)CN1C(=O)C1CCCO1 +NC(=O)c1cccc(C(=O)NC2CCCNC2=O)c1 +CCOCCOc1cccc(C(=O)Nc2ccc(Cl)c(N)c2)c1 +O=C(CCc1ccccc1)OCC(=O)c1c[nH]c2ccccc12 +Cc1ccc(OCc2nc3ccsc3c(=O)[nH]2)c(C)c1 +O=C(Nc1ncnc2c1CCC2)c1ccc2ncsc2c1 +CC(CNC(=O)Nc1ccc2c(c1)COC2)Oc1ccc(F)cc1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccccc2)c1C +CCCCn1nnnc1COC(=O)c1ccccc1O +CC(Sc1nccn1C)C(=O)Nc1ccc2c(c1)OCO2 +CCCCc1c(C)nc2nc(SCC#N)nn2c1C +CCCn1nnnc1CNc1ccc(Cl)cc1 +Cn1c(C(=O)NCC(=O)NCc2cccnc2)cc2sccc21 +CCOc1ccccc1OC(=O)COc1ccccc1 +COc1ccc(C(=O)N(C)Cc2cc(C)on2)c(F)c1 +O=C(NC1CCCCC1)NC1CCN(CC(F)(F)F)C1 +CC(NC(=O)NCc1cccs1)c1ccc(-n2cncn2)cc1 +CCn1nc(-c2ccc(OC)c(Cl)c2)cc(CC#N)c1=O +CCCS(=O)(=O)N1CCN(C(=O)C2CCCC2)CC1 +CCC1CC(=O)Nc2c1c(C)nn2-c1ccc(OC)cc1 +COc1ccccc1C(=O)NCC(=O)NC1(c2cccc(F)c2)CC1 +Cn1cncc1CN1CCc2nc3ccccc3c(=O)n2CC1 +O=S(=O)(Cc1c(F)cccc1F)NCc1nnc2ccccn12 +Cc1cnc(C(=O)Nc2ccc(Br)cc2C)cn1 +COc1ccc(NC(=O)C(C)Oc2ccccc2F)c(OC)c1 +COCC(O)CN(C)C(=O)Cc1ccccc1C +Cc1nn2cnnc2c(C)c1CCC(=O)Nc1cc(F)ccc1F +CCC1NCCc2ccc(C)c(Br)c21 +O=C(Nc1cccc(-c2cnco2)c1)c1cnc2ccccc2n1 +COc1cc(CNC(=O)Cc2cn3ccccc3n2)ccn1 +COc1cccc(SCC(=O)Nc2ccccc2SCC#N)c1 +CCS(=O)(=O)c1ccc(O)c(NC(=O)c2ccc(F)c(F)c2)c1 +c1ccc(-c2nc(Cn3ccnc3)nc3ccccc23)cc1 +CC1CCCC(NC(=O)Cc2n[nH]c(=O)c3ccccc23)C1C +CCCCc1cc(NC(=O)c2ccnc(SCC)c2)[nH]n1 +Cc1ccc(-c2cc(C(=O)NCCNc3ncccn3)[nH]n2)cc1 +CC(=O)N1CCCC(C(=O)NC2CCCCC2O)C1 +O=C(CCNC(=O)c1cccs1)OCC(F)(F)F +O=C(c1ccncc1)N1CCC2C1CC(=O)N2c1cncnc1 +CCOc1ccc(C(=O)Oc2cc(N)n(S(C)(=O)=O)n2)cc1 +Cc1cc(C)n(-c2cccc(C(=O)NCC(=O)N3CCCC3)c2)n1 +Cc1ccc(CO)cc1-c1ccc2c(c1)OCCO2 +Cc1cc(F)ccc1NC(=O)NCc1ccc(S(C)(=O)=O)cc1 +CC(C)c1nc(C2CCCN(C(=O)c3ccon3)C2)no1 +O=C(NC1CCC(O)CC1)NC(CC1CCOCC1)c1ccccc1 +COc1ccc(Nc2nc(-c3ccncc3)cs2)c(OC)c1 +CCOc1cccc(NC(=O)c2ccc(OC)c(OC)c2)c1 +COc1ccnc(N2CCCC(S(=O)(=O)N3CCOCC3)C2)n1 +CCc1n[nH]c(SCC(=O)Nc2ccc(C(=O)OC)cc2)n1 +CCCSc1ccccc1NC(=O)N1CCOCC1CO +CCc1noc(CN(C)C(=O)CCc2ccc(F)cc2)n1 +Cc1ccc(N2CCC(C(=O)Oc3ccccc3F)C2=O)cc1 +CC(=O)c1c(C)nc(C)nc1SCc1nc(C)c2ccccc2n1 +CC(=O)Nc1ccc(Oc2nc3ccccc3o2)cc1 +CC(=O)N1CCC(NS(=O)(=O)c2ccc(Cl)cc2C)CC1 +COc1cc(C)c(C(=O)NCC2(O)CCCCCC2)cc1OC +CCNC(=O)N1CCc2ncnc(NCCc3cnccn3)c2CC1 +CNC(=O)CC1CCN(C(=O)NC2CCCC2)CC1 +COc1cccc(NC(=O)CNC(=O)c2ccccc2)c1 +CCc1ccc(-c2noc(Cn3nc(C(N)=O)ccc3=O)n2)cc1 +Cc1ccc(-n2ccnc2)c(C(=O)NCCNC(=O)c2cccnc2)c1 +CN(C)C(=O)c1ccc(CNS(=O)(=O)c2ccccc2)cc1 +CC(=O)Nc1nc(C(=O)NC(C)c2ccc(F)c(F)c2)cs1 +COc1c[nH]c(C(=O)N2CC3CC=C(C)CC3C2)cc1=O +Cc1csc(NC(=O)c2ccccc2NC(=O)c2ccccc2)n1 +Cc1cccc(-n2nnnc2SCC(=O)N(C)c2ccccc2)c1 +CCOCC1CCCN(C(=O)Nc2cccnc2-n2cncn2)C1 +O=C(Nc1nncs1)c1cccc(NC(=O)C2CCCO2)c1 +COC(=O)Cc1cc(OC(=O)c2ccc(Cl)cc2)n(C)n1 +Nc1nnc(-c2cccc(-c3nc(C4CCOCC4)cs3)c2)o1 +CCCn1c(N)c(NCCN2CCOCC2)c(=O)[nH]c1=O +NS(=O)(=O)CCNC(=O)Nc1cccc(Cl)c1 +C=C(C)CN(CC)C(=O)CS(=O)(=O)c1ccc(C)c(C)c1 +O=C(NCC(=O)N1CCCC1Cc1cccc(F)c1)C1CCCC1 +Cc1ccccc1C(=O)NC(C)c1ccc(S(N)(=O)=O)cc1 +O=C(Nc1cccc(NC(=O)c2ccncc2)n1)c1ccncc1 +O=C(C1CC=CCC1)N1CCN(Cc2nnc3n2CCCCC3)CC1 +Cc1ccc(C)c(C(=O)CSc2nnc(C(C)C)o2)c1 +Cc1ncc(CNC(=O)Cc2ccc(OC(F)F)cc2)s1 +CCc1nn2c(CNC(=O)C3CCCCC3)c(C)nc2s1 +CCC(=O)N1CCN(S(=O)(=O)c2ccc(C(C)=O)cc2)CC1 +Cc1nc2c(c(C)c1CC(=O)N1C(C)CCCC1C)c(=O)[nH]n2C +Cc1cccc(S(=O)(=O)NCC(=O)N2Cc3cncnc3C2)c1 +CCNC(=O)CN1CCN(C(=O)c2ccc3[nH]cnc3c2)CC1 +COc1ccc(C)cc1NC(=O)c1ccc(CNC(C)=O)cc1 +Cc1cnn(CCNc2ncnc3ccccc23)c1 +Cc1cc(C(=O)Nc2nc3c(s2)CCC3)n(C(C)C)n1 +Cn1nccc1CNc1ccc(Cl)c2ncccc12 +O=C(OCC(=O)N1CCCC1)c1ccc(-n2cnnn2)cc1 +CC(=O)c1ccc(OCC(=O)Nc2ccccc2Br)cc1 +COc1cc(CNS(=O)(=O)c2c(F)cccc2F)ccn1 +CN(CCC(F)(F)F)C(=O)c1cc(C2CC2)n(C(C)(C)C)n1 +Cn1c(C(=O)N2CCCCC2c2cc[nH]n2)cc2cc(F)ccc21 +Cn1nc(C(=O)NCC(C)(C)C(N)=O)ccc1=O +CC(C)(C)NC(=O)NCC1CCN(C(=O)Oc2ccccc2)CC1 +COC(C)(C)c1noc(C2CCN(c3ncccn3)CC2)n1 +CC1(C)Cc2c(sc3ncn4nc(-c5cnccn5)nc4c23)CO1 +O=C(NCc1cc2ccccc2o1)N1CCOCC1C1CC1 +Cc1ccoc1C(=O)Nc1ccccc1OCC1CC1 +CCC(C)(C)C(=O)Nc1cnn(-c2ccccc2F)c1 +Brc1ccc2nc(-c3ccncc3)[nH]c2c1 +CC(C)N(CCC#N)C(=O)c1cccc(-n2cnnn2)c1 +Cc1c(S(=O)(=O)NCC2CCCO2)cnn1C +CC(C)C(C)NC(=O)CCC(=O)c1cccs1 +COc1ccc(F)c(NC(=O)c2c(C)nc(C3CC3)nc2SC)c1 +Cc1ccc(NC(=O)CSc2nnc(C(F)(F)F)n2C)cc1 +Cc1ccc(OCCC(=O)OCC2CCC(=O)N2)c(C)c1 +N#Cc1c2n(c(=O)n(Cc3cccc4ccccc34)c1=O)CCCCC2 +COc1ccc(C(O)CNc2ccc(C#N)cc2)cc1Cl +O=C(Cn1cnc(C2CCC2)cc1=O)Nc1ccc(OC(F)F)cc1 +COc1cc(C#N)cc(Cl)c1OCC(=O)Nc1ccccc1C#N +C#CCN1CCN(CCOc2ccc(C#N)cc2OC)CC1 +COc1ccccc1OCCNC(=O)Cc1ccccc1Cl +COCCn1nc(C(=O)N2CCCC2c2noc(C)n2)ccc1=O +CC1CN(C(=O)CCC2CCCO2)c2ccccc21 +CC(C)C(=O)N1CCN(C(=O)c2ccc(S(C)=O)cc2)CC1 +Cc1cccc(NC(=O)c2onc(-c3ccccc3C)c2N)c1 +O=C(OCCN1CCOC1=O)c1cccc(Cl)c1 +CC(C)(C#N)C(=O)NCCOc1cccc(Cl)c1 +CC(=O)N1CCc2cc(S(=O)(=O)N=c3[nH]cccc3C)ccc21 +CC(C)c1ccc(C2CC2C(=O)NCCCN2CCOC2=O)cc1 +CCNCc1nc2cc(OC)c(OC)cc2c(=O)[nH]1 +Nc1cccc2c1nc(C1CCCCC1)n2CCCO +Cc1ccc(OCc2nc(CC(=O)Nc3nccs3)cs2)cc1 +CC(C)Cn1nccc1NC(=O)c1cnc(Cc2ccccc2)s1 +Cc1nc2ccccc2nc1Cn1ncc(N(C)C)cc1=O +Fc1cc2c(cc1F)C(CCOc1ccccc1)NCC2 +CCOC(=O)CNC(=O)NCc1cccc(C)n1 +COc1ccc(CCNC(=O)c2cccc(Oc3cnccn3)c2)cc1 +COc1ccc(OC)c(S(=O)(=O)N(C)C(C#N)C(C)C)c1 +CCCC(=O)Nc1nc2c(s1)CN(S(=O)(=O)C(C)C)CC2 +CC(CC#N)C(=O)N1CCC(Cc2ccccc2)CC1 +COc1ccsc1C(=O)OCCc1c(C)n[nH]c1C +CN(CC(=O)NC1CC1)C(=O)CN1CCN(c2ccc(O)cc2)CC1 +CC(=O)c1ccc2c(c1)CCN2Cc1cccc(OCC#N)c1 +CCn1cc(C#N)c(=O)n(CC=Cc2ccccc2)c1=O +CN(CCCc1n[nH]c(N)c1C#N)c1nc2ccccn2c1C#N +CCNC(=O)C1CC(NC(=O)CO)CN1Cc1ccc(C)s1 +CCn1ccc(-c2cc(C(=O)OC)n3nc(C)c(Cl)c3n2)n1 +Cc1ccc(CN2CCN(C(=O)Cn3cc(Cl)cn3)CC2=O)cc1 +COC(=O)C1CN(c2cccc(F)c2)CCC1=O +CCOc1ccccc1NC(=O)c1cnc(C2CC2)nc1N +Cc1nc(C(=O)N2CC(C)Sc3ccccc32)cs1 +NC(=O)CNC(=O)Cc1c(Cl)cccc1Cl +Cc1cccc(CNC(=O)c2cc3ccccc3c(=O)[nH]2)c1 +O=C(NC1C2CCc3ccccc3C21)c1cccnc1OCC(F)F +NC(=O)C1CCCCN1C(=O)CCC1CCCO1 +CC(C)C(NC(=O)Nc1ccc(F)cc1)C(=O)N(C)C +O=C(Cn1nc(-n2cccn2)ccc1=O)Nc1cccnc1 +CS(=O)(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2Cc1ccccc1 +CCC12CC3CC(C1)CC(NC(=O)CSc1nnc(C)o1)(C3)C2 +CC(C)N(C)S(=O)(=O)c1cccc(C(=O)N2CCCC(O)C2)c1 +Cc1cc(C(=O)N(C)CC2CC2)c2ccc(F)cc2n1 +O=C(CNc1ccn(-c2ncccc2Cl)n1)Nc1ccccc1F +Cn1nc(C2CC2)c2cnn(-c3ccc(F)cc3)c2c1=O +CCc1cc(N2CCN(C(=O)N3CCOCC3)CC2)n2ncnc2n1 +CC(C)Oc1ccc(C(=O)OCC(C)(C)C)cn1 +Cc1nnc2n1CCN(C(=O)c1ccccc1Oc1cccnc1)C2 +N#CC(Sc1nnnn1CC(F)(F)F)C1CCCCC1 +CC(C)(C)OC(=O)N1CCC(Oc2nc3ccccc3o2)CC1 +O=C(NCc1cccnc1-n1ccnc1)c1cc(=O)[nH]c2ccccc12 +O=C(OCCN1C(=O)c2ccccc2S1(=O)=O)C1CCOCC1 +CC(C)C(NC(=O)c1ccc2ncnn2c1)C(=O)N1CCOCC1 +CC(C)n1ncc2c(C(=O)Nc3nncs3)cc(C3CC3)nc21 +O=C(C1CCCCC1)N(Cc1ccco1)CC1CCCO1 +O=C(Cc1cccc(O)c1)NCC1CN(Cc2ccccc2)CCO1 +Nc1ccc2nc(SCC(=O)NC3CC3)sc2c1 +O=C(Cn1nnc2sc3c(c2c1=O)CCCC3)Nc1ccccc1 +Cc1nn(C)c2c(=O)n(C)c(N3CC(C)CC(C)C3)nc12 +CCOc1ccc(OCc2nc3c(s2)CCN3)cc1 +COCCc1nccc(-c2cn(-c3ccc(C)cc3)nc2C)n1 +c1cc(CN2CCOC3C(Cn4cnnc4)CCC32)cs1 +O=C(c1ccncn1)N1CC2CN(Cc3cccnc3)CCOC2C1 +Cc1nc(CC(=O)NCc2cc(N3CCOCC3)ncn2)cs1 +N#Cc1ccc(N2CCN(Cc3cccc(F)c3)CC2)nc1 +NC(=O)c1cc(N)cnc1N1CCCCC1C(N)=O +CCCc1cc(-c2nc(-c3ccc(C#N)cn3)no2)[nH]n1 +CC(C)c1nc(CN(C)Cc2ccccc2-n2cccn2)co1 +Cc1cccc(OC2CCN(C(=O)c3cc(C(C)C)nn3C)CC2)c1 +Cc1ccc(C)n1-c1nc2ccc(C(=O)N3CCOCC3)cc2s1 +CC1CCCN(C(=O)c2cccc(S(C)(=O)=O)c2)C1 +c1csc(-c2noc(CNc3ccccc3-n3cccn3)n2)c1 +CNC(=O)c1cn(Cc2cccnc2)c2cccc(N)c2c1=O +Cc1cccc(OC(C)C(=O)N2CCN(Cc3cc(C)on3)CC2)c1 +COc1ccc(-c2nc(Cn3cnc(C)n3)c(C)o2)c(F)c1 +CN1CC(C(=O)Nc2ccc(OC(F)(F)F)cc2)CC1=O +O=C(COc1ccccc1)Nc1ccc(Oc2cnccn2)cc1 +CN(C)c1ncc(-c2nccn2Cc2cccc(-n3cccn3)c2)cn1 +CCCN(CC(=O)NC)c1ccc(C(=O)Nc2ccccc2)nn1 +Cc1cc(OCC(=O)Nc2nnc(C3CC3)s2)ccc1C(C)C +COC(=O)N(C)Cc1ccc(NCc2noc(C(C)C)n2)cc1 +NC(=O)C1CCN(C(=O)C2(c3ccccc3F)CCCC2)C1 +CC1CN(C(=O)c2cccn2C)CC12CCN(c1ccsc1)C2=O +Cc1nn(C)c2ncc(CN3c4ccccc4CC3C)cc12 +COc1cccc(CNC(=O)c2cccc(OC)c2F)n1 +COCC(NC(=O)c1ccc(Oc2ccccc2)cc1)C(N)=O +CCc1cccc(C)c1NC(=O)CC(NC(N)=O)c1ccccc1C +CC(C)Oc1ccc(-c2csc3nc(N)cn23)cc1 +CCN(Cc1ccc(C(N)=O)cc1)Cc1cccs1 +NC(=O)c1nc2cc(Br)ccn2c1N +CCCC(C)(C)NS(=O)(=O)c1ccc(OC)cc1 +COc1ccc(C2(C(C)=O)CCCCC2)cc1OC +COc1cccc(C(=O)NC2CCC(=O)CC2)c1O +O=C(Nc1cccnc1)C(C(F)(F)F)C(F)(F)F +NS(=O)(=O)c1ccc(NC(=O)Cc2c(F)cccc2F)c(F)c1 +COc1ccc2oc(C(=O)N3CCCC(CNC(C)=O)C3)c(C)c2c1 +CCCC(C)C(=O)Nc1ccnc(C(=O)N(C)C)c1 +Cc1ncsc1C(=O)N(C)CC(=O)NC(C)(C)C +CS(=O)(=O)c1nc2ccccc2n1CC(=O)N1CCCCC1 +CC(=O)NCCNC(=O)CSc1cccc(Br)c1 +CS(=O)(=O)c1cccnc1C1CCCN(C(=O)c2ccncc2)C1 +CCCOc1ccc(CNC(=O)Nc2nnc(C3CC3)s2)cc1 +CCCC1=C(C(=O)OC)C(c2ccc(C)o2)NC(=O)N1C +COc1c(CNC(=O)NC2CCC(C)c3ccccc32)c(C)nn1C +CCS(=O)(=O)NCCSc1nnc(C)n1N +COC(=O)c1ccc(CC#N)cc1S(N)(=O)=O +Cc1cc2ccccc2n1CC(=O)Nc1c(F)cccc1-n1cncn1 +COc1ccc(F)cc1C(C)NC(=O)Nc1cc(C)nn1C +N#CC1CN(Cc2ccc(Sc3ccccc3)cc2)CCO1 +Cc1ccncc1NC(=O)N1CC(C)OC(c2ccsc2)C1 +COC(=O)c1ccccc1NC(=O)COc1cccc(C#N)c1 +O=C(CCC1CCCO1)Nc1cccc(-n2cnnc2)c1 +O=c1oc2ccc(F)cc2cc1S(=O)(=O)c1ccc(F)cc1 +Cc1[nH]nc(O)c1C(c1ccncc1)C(C#N)C#N +Cc1cc(C)cc(NC(=O)Cc2nnc(-c3ccsc3)o2)c1 +COc1ccc(N(C)S(=O)(=O)c2cc(F)ccc2F)cn1 +Cc1nn2c(=O)c(C(C)C)c(C)[nH]c2c1-c1ccncc1 +Cc1ccc(CCNC(=O)CNC(=O)c2cc(C)n(C)n2)o1 +CC(C)c1nc(Cn2c(=O)cnc3ccccc32)no1 +O=C(Nc1ccc(-c2nc3ncccc3o2)cc1)c1cccnc1 +Cn1c(CNC(=O)C2(c3ccccc3)CCOCC2)nc2ccccc21 +COc1ccc2c(c1OC)C(C(=O)N1CCCC1)CC2=O +CCOC(=O)C(C)NC(=O)c1ccc(Br)cc1F +COC(=O)c1c(NC(=O)CNC(=O)C(C)C)c(C)nn1C +O=C(NCc1nnc2n1CCCC2)Nc1cn[nH]c1 +COC(=O)C(Nc1ccc2oc(=O)[nH]c2c1)c1cccc(C#N)c1 +Cc1cc(C)n(Cc2cccnc2)c1C(=O)NCc1ccco1 +CCC(O)Cn1nc(C)nc1-c1c(F)ccc(OC)c1F +CCN(Cc1noc(C2CCC2)n1)Cc1ccccc1C#N +O=C(CCc1nc2c(F)cccc2[nH]1)NCc1csc(=O)[nH]1 +CCn1ccc2ccc(NC(=O)c3ccccc3OCC(N)=O)cc21 +CCCNS(=O)(=O)c1ccc(NCc2c[nH]nc2C)cc1 +CCn1cnnc1SCC(=O)Nc1cc(C(=O)OC)ccc1C +Cc1cc(C(=O)Nc2ncn(Cc3ccc(F)cc3)n2)c(C)o1 +COc1cccc(NC(=O)C2CC(=O)N(Cc3ccc(F)cc3)C2)c1 +N#CCCN(CC1CCC1)S(=O)(=O)c1c[nH]c2ncccc12 +COC(=O)NCC(=O)NC1(C(=O)OC)CCCC1 +Cc1cc(NC(=O)N(C)Cc2ccc(C(C)C)cc2)n(C)n1 +CC(Cn1ccnc1)NS(=O)(=O)c1ccc(C#N)c(Cl)c1 +Cc1nc(-c2ccc(CNC(=O)c3ccccc3)s2)cs1 +CC(=O)Nc1ccc(Cl)c(NCC(=O)Nc2ccc(F)cc2)c1 +CS(=O)c1ccc(NC(=O)c2ccc(C(F)(F)F)nc2)cc1F +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccccc1C(F)(F)F +COc1ccc(C(=O)Nc2cc(=O)oc3ccccc23)cc1OC +CSc1nnc(SCc2nc3ccccc3[nH]2)s1 +N#Cc1cccc(Sc2ccc3nccnc3n2)c1 +CS(=O)(=O)NC1CCCN(C(=O)c2ccc3c(c2)CCO3)C1 +Cc1nn(C)c(C)c1C(=O)Nc1cccc(NC(=O)C(C)(C)C)c1 +CC(=O)c1ccc(Cl)c(S(=O)(=O)Nc2c[nH]nc2C)c1 +Cc1nc(C)c(CC(=O)N(C)Cc2ccc(C)s2)c(=O)[nH]1 +CCC(=O)Nc1ccn(Cc2cccc3cccnc23)n1 +CCC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +O=C1CCCN1c1cccc(C(=O)N2CCCCC2c2ccccn2)c1 +CCn1cc2c(n1)CN(Cc1ccoc1)CC2COCC1CC1 +CCCCCCNC(=O)C1CC(=O)N(C(C)(C)C)C1 +Cn1nccc1NC(=O)Cn1cc(-c2ccnc(N)n2)cn1 +CN(CCc1ccccc1)C(=O)c1ccc[nH]c1=O +Cc1nc2nc(-c3ccc4c(c3)CCO4)cn2nc1C +CC(C)(C)NC(=O)CNC(=O)NCC(=O)NC1CC1 +Cc1ccc(C)c(-n2c(C)nnc2SCC(=O)NC(C)CO)c1 +Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CCOC(C)C +N#Cc1cccc(C(=O)OCC(=O)NC2CCCCC2)c1 +CCC1CCCN(C(=O)c2c(C)nc(-c3ccco3)nc2SC)C1 +Cc1[nH]c2ccccc2c1C(=O)NS(=O)(=O)c1ccccc1Cl +CC(C)CC(C(=O)N=c1[nH]nc2ccccn12)N1CCCCC1=O +O=C(Cc1noc(CCn2ccccc2=O)n1)NCc1ccccc1 +Cc1ccc(C)c(CNc2ccc(Cl)c(C(N)=O)c2)c1 +COCC(C)NC(=O)Nc1ccc(C(C)=O)c(C)c1 +CC(C)c1ccc(S(=O)(=O)Nc2cccc(NC(=O)CO)c2)cc1 +Cc1ccc(S(=O)(=O)CC(=O)N2CCCCCC2)cc1 +CSc1nc(N)c(NC(=O)c2ccccc2)c(=O)[nH]1 +CSc1cccc(NC(=O)Nc2ccc3[nH]c(=O)oc3c2)c1 +COC(=O)CNC(=O)NC(C)C(=O)N1CCc2ccccc21 +CCOC(=O)Cn1c(-c2cccc(N)c2)csc1=O +CCc1ccccc1NC(=O)CN(C)C(=O)CNC(=O)NC +CCC(=O)N1CCCN(C(=O)c2ccc(-n3ccnn3)cc2)CC1 +Cc1ccnc(NC(=O)c2cc(Cl)ccc2Cl)n1 +COc1cccc(F)c1C(=O)NC(C)c1ccccc1 +COc1ccc(OCC2Cc3c(nc(N)c(C#N)c3N)O2)cc1 +CNC(=O)c1csc(Nc2ccc(OC(F)(F)F)cc2)n1 +O=C(NCC1Cn2ccnc2CO1)c1ccc(F)cc1 +CCc1noc(CC)c1CC(=O)N1CCN(Cc2cc(C)no2)CC1 +CC(C)(C)c1noc(CCC(=O)N2CCc3sccc3C2)n1 +COc1ccc(O)c(C(=O)N2CCN(Cc3ccncc3)CC2)c1 +O=C(c1ccoc1)N1CCC(Nc2cccnc2)C1 +N#Cc1c(F)cccc1NCCNc1nc2ccccc2o1 +Cc1cccc(C)c1Oc1ncccc1CNC(=O)c1[nH]cnc1C +CCc1c(C(=O)N2CCc3ccccc3C2)cnn1Cc1ccccc1 +CCOc1ccc(-c2noc(CS(=O)(=O)c3nccn3C)n2)cc1 +COc1cccc(COC(=O)Cn2cc(C)cn2)c1 +COC(=O)c1ccc(C(=O)NCc2ccccc2C)cc1 +CC1CCCN(C(=O)c2csc(Nc3ccccn3)n2)C1 +O=C(NCCn1cccn1)c1cc(COc2ccccc2)[nH]n1 +CCOc1ccccc1CNC(=O)Cn1ncc2ccc(C)cc21 +CCOc1cc(C)ccc1NC(=O)c1ccc(C(=O)OC)cn1 +CCn1ccc(Cn2ccc3ncccc3c2=O)n1 +O=c1[nH]c(-c2ccc(Br)cc2)cn1C1CC1 +CCc1n[nH]c(C(=O)N(C)C(C)CC(=O)NC)c1C +C=C(C)COc1cccc(NC(=O)NC(C)COC)c1 +CC(C)(C)c1cc(CN2CCN(c3ccc(C(N)=O)cn3)CC2)n[nH]1 +CN(Cc1ccncc1)C(=O)Nc1cccc(N2CCCCC2)c1 +Cc1nn(C)c(N)c1S(=O)(=O)NC(C)c1ccccc1 +CNC(=O)CCNc1ccc2nnc(C(F)(F)F)n2n1 +N#Cc1ccccc1OCC(=O)Nc1ccc2c(c1)OCCO2 +CN1CC(NC(=O)c2ccc(C(F)(F)F)cc2)CC1=O +Cc1noc(C)c1CN1CCN(C(=O)CSc2ncn[nH]2)CC1 +Cc1ccc(OCCNC(=O)N2CCC(CC(N)=O)CC2)cc1 +COc1ccccc1-n1nnnc1SC1CCOC1=O +O=C(COc1ccccc1F)Nc1cc(-c2ccco2)nn1CCO +O=C(Cn1nnn(-c2ccccc2Cl)c1=O)c1ccccc1 +COc1ccc(CN2CCOCC2c2ccc(C)o2)c(OC)c1 +CCCCC(Nc1nccc(-c2ccccn2)n1)c1cccnc1 +c1ccc(-c2csc(CCNCc3cccc4[nH]ccc34)n2)nc1 +Cc1n[nH]c(C2CN(CC(=O)NCC3CCCO3)CCO2)n1 +CC(=O)N1CCC(C(=O)Nc2sc(C)c(C)c2C(N)=O)CC1 +CC(C)NC(=O)N1CCN(CC(=O)c2ccco2)CC1 +Clc1cc(NCc2nnc3n2CCCCC3)nc2[nH]ccc12 +COc1ccc2nc(C)c(C(=O)N3CCOCC3)cc2c1 +CC1CCN(c2nn3c(=O)c(C(=O)NC4CC4)cnc3s2)CC1 +CC(C)Cc1nnc(NC(=O)c2cc(C(N)=O)cn2C)s1 +CC(C)CCc1noc(COc2nnc3ccccn23)n1 +O=C1CC(C2CCCC2)c2c(-c3ccco3)n[nH]c2N1 +CCCCNC(=O)Cc1noc(Cc2ccc(C)o2)n1 +Cc1nc(CCCN2CCOCC2)n(Cc2ccc(F)cc2)n1 +Cc1nc2cc(C(=O)Nc3nccs3)ccc2n1-c1ccccc1 +N#Cc1cn(C2CC2)c(=O)n(Cc2ccccn2)c1=O +COc1ccnc(NC(=O)C(C)OCC2CC2)c1 +O=C(CCc1c[nH]c2ccccc12)OCC(=O)c1cccs1 +COc1cc2c(cc1OC)C(=O)C(Sc1nc(N)cc(=O)[nH]1)C2 +COC(=O)c1cc(Cl)cc(NCc2cccc(C(N)=O)c2)c1 +CC(=O)N1CCC(C(=O)OCCc2c[nH]nc2C(F)(F)F)CC1 +CCN(CCn1c(=O)oc2cccnc21)c1ccccc1 +CN(CCC#N)S(=O)(=O)NCc1cccs1 +COc1ccccc1OCCNC(=O)C1CCN(C(C)=O)CC1 +COC(=O)c1sccc1NC(=O)c1cccc(Cl)c1 +Cc1nc2ccc(NC(=O)NCCc3ccccc3)cc2o1 +COc1cccc(C(=O)NCc2cccc(C)n2)c1F +CCCC(=O)N1C2CCC1c1cnc3cc(-c4ccco4)nn3c1C2 +Cc1csc2nc(CN3CCSc4ccccc43)cc(=O)n12 +O=C(NCCOc1ccccc1)c1cccnc1SC(F)F +CC(CNC(=O)c1ccc(F)nc1)Oc1ccccc1 +COc1cccc(C2CCN2C(=O)c2ccc(-c3nnn(C)n3)cc2)c1 +CCOC(=O)c1c(C)csc1NS(=O)(=O)c1ccc(C)cc1 +CNC(=O)c1cccc(NCc2ccc(F)cc2C)c1 +CCOc1cc(CNC(=O)c2scnc2C)ccc1OC(F)F +CC(C)c1nc(CN(C)S(=O)(=O)NCc2ccccc2)cs1 +CCc1onc(C)c1NC(=O)Cc1ccc(C(F)(F)F)cc1 +COC(=O)Cc1cc(=O)c2cc(Br)ccc2[nH]1 +CCCc1cc(NC(C)c2csc(C)n2)n2nccc2n1 +O=C(Nc1ccccc1)N1CCN(C(=O)c2ccccc2O)CC1 +CCOC(=O)c1ccc(N(CC)CCC#N)c(N)c1 +CCOCC1CC2OCCN(S(=O)(=O)c3cn(C)cn3)C2C1 +COc1ccc2c(C(=O)NCc3cnn(C)c3C)cc(=O)oc2c1 +CCOCC(=O)Nc1ccnn1Cc1ccc(C(C)(C)C)cc1 +CCCS(=O)(=O)NCc1ccc(C(C)(C)C)cc1 +Cc1nn(C)c(C)c1S(=O)(=O)NCCC(=O)N1CCCCC1 +COc1cccc2cc(C(=O)OC(C)c3ccccn3)oc12 +CCNC(=O)c1ccc(NC(=O)NCC2CC2C)cc1 +N#Cc1nnc(-c2ccccc2)nc1N1CCOCC1 +Cc1ccc(C)c(S(=O)(=O)N2CCCCCC2)c1 +CC1C(=O)N(C)CCN1C(=O)c1c[nH]nc1-c1cccc(F)c1 +O=C(NCCc1cccs1)C1CC(=O)N(C2CCCC2)C1 +COC(=O)c1cccc(NC(=O)Cc2ccc(F)cc2)c1 +Cn1nc2c(cc1=O)CN(Cc1ccccc1Oc1cccnc1)CC2 +Cc1ccc(CC(=O)NCCc2nc3c(s2)CCCC3)s1 +Cc1ccc(CCNC(=O)c2ccc(-n3ccnc3)nc2)c(C)c1 +CNC(=O)C1CCN(S(=O)(=O)c2ccc(OC)cc2)CC1 +CC(=O)c1c(C)nn(CC(=O)Nc2ccnn2C2CCCCC2)c1C +Cc1n[nH]c(C)c1CCC(=O)Nc1ccc(-n2ccnc2)cc1 +O=C(NCc1cccnc1-n1ccnc1)c1ccc(Cl)cc1 +COc1ccc(CN2CCN(C(=O)c3ccccc3)CC2)cc1OC +Cc1nc2cc(NC(=O)c3cccc(Oc4cnccn4)c3)ccc2o1 +CC(C)Cc1nc2n(n1)C(C(=O)NCCc1ccccc1)CC(=O)N2 +Cc1csc(N2CCN(C(=O)c3ccc[nH]3)CC2)n1 +Cc1[nH]ncc1CCCNC(=O)N1CCC(Oc2ccccc2)CC1 +COc1ccc(C)cc1C(N)c1c(C)cc(C)n(C)c1=O +O=C(NCc1nc(-c2ccc(F)cc2)n[nH]1)c1ccc(O)c(Cl)c1 +CN(C)c1ccc(NC(=O)c2ccc(F)cc2)cn1 +Nc1ccnc(CNC(=O)c2ccc(OC3CCC3)cc2Cl)n1 +COc1ccccc1C(O)CCCC(=O)N1CCC(C)CC1 +Cc1cc(C)nc(NC(=O)COc2cccc(Cl)c2)c1 +CCOC(=O)N1CCC(OC(=O)c2cc(C(C)C)[nH]n2)CC1 +Cn1c(SCC(=O)Nc2nccs2)nnc1-c1ccc(F)cc1 +CC(=O)N1CCCC1C(=O)Nc1ccccc1C(=O)NC1CC1 +CN(Cc1cnn(C)c1)C(=O)NCCCc1ccccc1 +CCc1c(C)nc2n(c1=O)CC(C(=O)N(C)C1CCCCC1)CS2 +CC1CN(C(=O)Cc2cc(-c3cc4ccccc4o3)on2)CC(C)O1 +N#CCc1ccc(OCC(O)CSc2cc(C#N)ccn2)cc1 +Cc1c(Cl)cccc1NC(=O)Nc1ccc(C(N)=O)cc1 +N#CCCn1c(Cc2ccc(F)cc2)nc2ccccc21 +COC(=O)C(NC(=O)Cn1c(=O)cnc2ccccc21)C(C)C +O=C(Cn1c(CO)nc2ccccc21)Nc1cccc(F)c1 +CCN(CC)C(=O)CNC(=O)c1ccc(Br)cc1 +O=C1CCN(Cc2cc(O)ccc2Br)CCN1 +CC(=O)Nc1nc(C(=O)NCCOc2ccc3c(c2)OCO3)cs1 +COc1cccc(OC)c1-c1nc(C#N)c2ccccn12 +O=C(OCC1CCCCO1)C1CC(=O)N(CC2CC2)C1 +Cc1sc(=O)n(CC(=O)N2CCOc3ccccc32)c1C +COc1ccccc1CCNC(=O)CSc1nc2ccccc2o1 +N#Cc1ccccc1OCC(=O)NCc1nc(-c2cccnc2)n[nH]1 +Cc1[nH]ncc1CCCNC(=O)NC(C)c1ccccc1Cl +Cc1cc(C(=O)N2CCCCC2C)ccc1NC(=O)Cc1ccc[nH]1 +COCCS(=O)(=O)N(C)c1ccc(Br)cc1C +CCOc1nn(CC)cc1C(=O)Nc1ccc(C)c(C)c1 +Cc1ccc2oc(-c3nccn3CCCN3CCCC3=O)c(C)c2c1 +COC(=O)c1cccc(CCNC(=O)c2ccc(C)[nH]c2=O)c1 +CC(O)(c1nccn1-c1ccncc1)C(F)(F)F +COc1c(C)cnc(CNC(=O)N(C)Cc2ccccc2F)c1C +COc1ccc(NC(=O)Cn2ccccc2=O)c(N)c1 +CN(CC(O)C1CC1)C(=O)C(Cc1c[nH]c2ccccc12)NC(N)=O +CCn1nc(C(=O)Nc2onc3c2CCCC3)cc1C +Cc1cccc(-n2nnnc2SCC(=O)N(C)C(C)CC(C)C)c1 +CCN1C(=O)CCc2cc(NC(=O)c3cccc(OC)c3)ccc21 +COC(=O)c1ccc(C(=O)N2CCc3ccc(Cl)cc3C2)nc1 +CC(=O)Nc1nc2c(C)cc(NC(=O)Nc3ccccc3)cc2s1 +Cc1csc(SCC(=O)NCC2Cc3ccccc3O2)n1 +Cc1ccc(CC(=O)Nc2ccc(C#N)cn2)cc1 +CCCc1ccc(S(=O)(=O)Oc2cccc(CC(N)=O)c2)cc1 +Cn1ccnc(NC2CCC(C(N)=O)CC2)c1=O +C=CC(CC(=O)Nc1cccc(C(N)=O)n1)c1ccccc1 +CC(=O)N1c2ccccc2NC(=O)C1CC(=O)Nc1cccc(C)c1 +CC1CN(CCC(=O)Nc2ccccc2N)CCO1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)Nc1ccccn1 +Cc1sc(=O)n(CC(=O)NCCCc2ccccc2)c1C +Cc1cc(CN(C)C(=O)Cc2csc(N3CCCC3=O)n2)no1 +Cc1nc2c(c(C)nn2C)c(C)c1CCC(=O)NC(C)C1CCCO1 +COCC(C)NC(=O)C(NC(=O)c1ccc(Cl)cc1)C(C)C +CCC(C)n1ncc2c(C(=O)N(C(C)C)C3CCC3)cc(C)nc21 +CN(C)C(=O)c1cc(-c2csc(-c3cnccn3)n2)n2ccccc12 +Cn1cc(Br)cc1C(=O)Nc1cn[nH]c1 +CC(C)CCN1C(=O)C2(OCCO2)c2ccccc21 +O=C(CCc1nc(-c2ccsc2)no1)Nc1ccc(F)c(F)c1 +O=C(Cc1c(F)cccc1Cl)NCCc1ccc(O)cc1 +CCCN(Cc1ccc(C#N)cc1)C(=O)c1cc(F)cc(F)c1 +CC(CO)NC(=O)NCC(C)Oc1cccc(Br)c1 +COc1cccc(C(C#N)NCCc2ccc(F)cc2)c1 +CCc1cc(C(=O)NCCOCc2ccccc2)cc(=O)[nH]1 +CC(NC(=O)C(C)(C)C)C(=O)NCC(O)c1ccc(Cl)cc1 +COCCCNS(=O)(=O)c1cccc(C#N)c1 +COCCOCC1NCCc2c(F)ccc(Cl)c21 +CC(=O)NC1CCN(C(=O)Nc2cc(C3CC3)nn2C)C1 +O=C(NCCN1CCOC1=O)c1ccc2sccc2c1 +CN(C(=O)Cn1cnc2ccccc2c1=O)C1CCCCC1 +O=C(NC1CCc2cc(F)ccc21)NC1CCCc2occc21 +Cc1ccc(NC(=O)Cc2cccc(N)c2)cc1F +CC(C)N1CC(C(=O)Nc2ccc(Oc3ncccn3)cc2)CC1=O +COc1ccccc1OCCc1nc(C)c(CCO)c(=O)[nH]1 +O=C(c1ccc(O)c(Cl)c1)N1CCCC1c1ccncc1 +COCCCNC(=O)C(N)c1ccc(C)c(F)c1 +CC(=O)Nc1ccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +CC(C)c1noc(CCC(=O)NC(C)(C)c2ccc3c(c2)OCO3)n1 +CCOC(=O)c1c(C)n(C)c2c(C)cc(O)c(OC(C)=O)c12 +O=C(NCc1ccc(N2CCCC2=O)cc1)c1ccc(F)cc1 +COCCNc1nc2nonc2nc1NC(C)c1ccccc1Cl +O=C(Cn1c(=O)cnc2ccccc21)Nc1ccc2c(c1)OCO2 +CCn1cc(C(=O)NCC(C)(C)c2ccccc2C)cn1 +COc1ccc(S(=O)(=O)NCC2CCN(c3ccccc3)C2)cc1 +Cc1ccc(OCC(=O)NCC(O)C2CCCCC2)cc1 +CCN(CC)c1ccc(C(=O)Nc2ccc(C(=O)NC)cc2)cc1 +c1csc(CN2CCCN(c3ncnc4[nH]ccc34)CC2)c1 +CS(=O)(=O)c1ccc(CNc2cccnc2)cc1 +O=C(CCSc1ncccc1Cl)Nc1cccc(F)c1 +CCc1c(C)sc2c1c(N)nc(=O)n2CCN1CCOCC1 +CNC(=O)c1cc(S(=O)(=O)N2CCCC(C(N)=O)C2)cn1C +CCCCCCn1c(=O)c2c(nc3oc(C)cn32)n(C)c1=O +CCn1cnnc1CNC(=O)c1cccnc1N1CCOCC1 +COC(=O)C(NCc1cccs1)c1cccc(F)c1 +FC(F)Cn1cc(NCc2cnc(C3CCCC3)s2)cn1 +COc1ccc(CN(C(=O)Cc2c(C)nc(C)[nH]c2=O)C2CC2)cc1 +Cn1ccc2c(-c3nc4ccccc4cc3CO)ccnc21 +Cc1cc(C)c(C#N)c(SCC(=O)N(C)Cc2cccs2)n1 +C=CCn1c(SCc2csc(C)n2)nnc1-c1ccoc1C +CCCCS(=O)(=O)NCC(O)c1cc(C)ccc1C +CN(Cc1ccccc1)C(=O)c1cccc(N(C)S(C)(=O)=O)c1 +Cn1cccc1CNc1cccc(OC(F)F)c1 +CC(=O)Nc1ccccc1OCC(=O)Nc1ccc(Cl)cc1C +NC(=O)NC(CC(=O)NC1CCCCC1)c1ccccc1Cl +Cc1noc(C)c1CCCNS(=O)(=O)c1ccc(Cl)cc1 +COc1cccc(C(=O)NCCc2csc(C(C)C)n2)c1 +Cc1noc(C)c1CN(C)c1nc(-c2ccccc2)no1 +CCN1CC(C(=O)NCCc2nc3c(s2)CCCC3)CCC1=O +Cc1ccc(CN(C(=O)C2CC2)c2ccc3c(c2)OCCO3)s1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)Nc1nc[nH]n1 +Cc1cccc(C(=O)N2CCCCC2CNS(C)(=O)=O)n1 +C#CCNc1cc(S(=O)(=O)N(C)C)ccc1OCC +O=C(CCc1cc(F)ccc1Br)NCc1cccnc1 +CSc1ncnc(NCc2nc3ccccc3n2C)c1C#N +Cc1[nH]ccc1C(=O)NCCc1ccc(NC(=O)OC(C)(C)C)cc1 +Cc1cncc(C2NCCc3ccc(O)c(F)c32)c1 +COc1cccc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)c1 +Cc1ccc(NC(=O)N2CCC(Oc3cnccn3)CC2)cc1 +CNC(=O)NCC(=O)N(C)CCOc1cccc(Cl)c1 +Cc1noc(C)c1Cn1cc(C(F)(F)F)ccc1=O +CN1c2ncccc2C(=O)NC12CCN(C(=O)c1cccs1)CC2 +Cc1cc(F)cc(NC(=O)N2CC(C(N)=O)CCC2C)c1 +Cc1cc(-c2cc(CO)nn2C(C)C)ccc1Cl +COc1ccc(-c2nc3c(N)nc(N)nc3[nH]2)cc1 +COc1ccc(C(=O)Nc2ccc3c(c2)N(C(C)=O)CC3)c(OC)c1 +CN(Cc1ccsc1)C(=O)C1COc2ccccc2C1 +CC(=O)c1ccc(Nc2nccc3n[nH]c(=O)n23)cc1 +Nc1cccc(C=Cc2nc3ccc(N)cc3[nH]2)c1 +O=C(Cn1nccc1-c1ccncc1)N(Cc1ccsc1)C1CC1 +O=C1CN(S(=O)(=O)c2ccc(F)c(C(F)(F)F)c2)CCN1 +CC(C)NC(=O)N1CCC(C(=O)NCC(F)(F)F)CC1 +CCn1nc(C)c(NC(=O)Nc2ccc(-c3cc[nH]n3)cc2)c1C +CCCC(C)NC(=O)C1CCCN(C(=O)c2ccc(F)cc2F)C1 +CCC(CC)n1nc(C)cc1NC(=O)c1cccc2c1NCCC2 +N#CCc1nc2cccnc2n1-c1ccc(C#N)cn1 +COC(CNC(=O)Cc1cccc(F)c1)C(C)(C)C +COc1ccc(C(=O)Nc2ccc(N3CCNC(=O)C3)nc2)c(F)c1 +CC1CC(=O)c2cnc(NCc3ccco3)nc2C1 +Cc1nc2c(Nc3cnn(Cc4cccc(F)c4)c3)ncnc2[nH]1 +COc1ccc(-c2cn3nc(N)nc3cc2C)cc1 +O=C1NCCNC1(c1ccc(Cl)cc1)C1CC1 +CCOc1cc2c(c(Cl)c1O)C(CC(C)(C)C)NCC2 +O=C(CCCc1nc(-c2cccs2)no1)N1CCOCC1C1CC1 +O=S(=O)(NC1CCCC1)c1ccc(Br)cc1F +CC1CN(Cc2cn3ccccc3c2C#N)C(C)CO1 +Cn1nc(C(=O)N2CCCC2c2ccc(F)cc2)cc1C(F)(F)F +CCc1nc(CC(=O)N2CCC(C(O)c3ccccc3)CC2)cs1 +O=C(c1ccco1)N1CCCC2(CC(Oc3ncccc3F)CO2)C1 +C=CCc1ccccc1OC(=O)Cc1ccc(-n2cnnn2)cc1 +CCOc1ccccc1CN(CC)C(=O)c1cccc(C#N)c1 +CN(CCO)C(=O)COc1cccc(C(C)(C)C)c1 +CCOc1ccc(C(=O)Nc2cc(C)ccn2)cc1Br +CC(C)c1noc(CCC(=O)Nc2cc(Cl)c(N)c(Cl)c2)n1 +COc1ccc(C)cc1N1CC(C(=O)N2CC(C)OC(C)C2)CC1=O +COCCC(=O)NC1CCN(S(=O)(=O)C(F)(F)F)CC1 +CC(C)CN1CCN(C(=O)Cc2ccc(F)c(F)c2F)CCC1=O +CCOc1ccc(NC(=O)Nc2ccc3c(c2)N(C(C)=O)CC3)cc1 +CCC(C(=O)OC)n1cc(CO)c2cc(C)ccc21 +COCCOc1ccc(NC(=O)NCc2cnc(C)s2)cc1F +O=C(c1ccc(-c2cc[nH]n2)cc1)N1CC=C(c2ccccc2)CC1 +CCCOC1CCCN(C(=O)NCc2ccccn2)C1 +O=C(Cn1ccnc1)Nc1cc(C(F)(F)F)ccc1Cl +CCC(CC)N(CCOC)C(=O)c1cnc2ccc(C)cn12 +Cc1cc(C(=O)NC(C)CN2CCOCC2)no1 +CCOc1ccc(C(=O)Nc2nc(C)c(C)s2)nn1 +CCOC(=O)N1CCCC(C(=O)N2CCOc3ccc(F)cc32)C1 +Cc1cccc(C)c1NC(=O)C1Nc2cc(F)ccc2S(=O)(=O)N1 +CCN(CC)C1CN(c2cc(OC)ncn2)C2CCCOC12 +CC(C)(C(=O)NCc1ccc(-n2ccnc2)cc1)c1ccc(F)cc1 +CCOC1CCCN(C(=O)c2ccccc2NCc2cccnc2)C1 +COc1ccc(C(=O)NC(C)c2nc(C)cs2)nn1 +COc1cc(CNC(=O)N2CCNC(=O)C2)ccn1 +Cc1ccc(Cl)cc1NCCc1nccs1 +CC(C)Oc1ccc(C#N)cc1NC(=O)Nc1ccccn1 +Cc1cc(C)n(CC(C)CNC(=O)c2cc(Cl)ccn2)n1 +CC(C)NC(=O)CN1CCN(C(=O)NCc2cccc(F)c2)CC1 +O=C(CCn1ccccc1=O)Nc1nc(-c2ccc(F)cc2)cs1 +COc1ccc2c(c1)CN(C(=O)Cc1ccc3c(c1)OCO3)CC2 +CCN1C(=O)CCCC12CCCN(C(=O)c1cccs1)C2 +COc1cccc(OC)c1CC(=O)Nc1cc(C)cc2cccnc12 +CN1CCOC(c2noc(Cc3ccccc3Br)n2)C1 +Nc1ccc(NCc2ccccc2)c(Br)c1 +O=C(CN1CCN(Cc2cccc(Cl)c2)CC1)N1CCCCC1 +COc1ccc(S(=O)(=O)Nc2c(F)cccc2F)cc1OC +N#Cc1ccsc1NC(=O)c1ccc2c(c1)NC(=O)CS2 +O=C(CCn1ccccc1=O)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1ccccc1C(C)NC(=O)CCc1ccco1 +COc1ccc2c(c1)CC(Cc1ccncc1)C2=O +CCC(=O)NCC1CCN(C(=O)Nc2ccc(F)cc2)CC1 +CCOC(=O)c1[nH]c(C)c(C(=O)Nc2ccc(C)cc2)c1C +Cc1nc(S(=O)(=O)N2CCN(c3ccccc3F)CC2)cn1C +CC(NC(=O)NC1CCCC1)C(=O)NCC(F)(F)F +CCN(CC)C(=O)COc1cccc(NC(=O)N2CCCC(C)C2)c1 +O=C(Cn1c(=O)c(C(F)(F)F)nc2ccccc21)NC1CCCC1 +CC(=O)Oc1ccc(CN2CCn3c(nn(C)c3=O)C2)cc1 +COc1ccc(-c2noc(C=Cc3ccncc3)n2)c(OC)c1 +CN(Cc1ccco1)C(=O)c1csc(-c2ccsc2)n1 +O=C1NCCN1S(=O)(=O)c1sccc1Br +Cc1noc(C)c1C1CCCN1C(=O)c1ccsc1 +CCOCCC(=O)Nc1ccc(Br)c(C)c1 +CCc1nnc(C2CCN(C(=O)NC3CCCCC3)CC2)s1 +N#Cc1ccc(-n2c(=O)[nH]c3cccc(F)c32)nc1 +CCC1CC(NC(C)=O)CC(c2cnn(CC)c2)O1 +COc1ccccc1N1CCN(Cc2ccc(=O)n(C)c2)CC1 +CCn1c(Cn2cnc3ccccc3c2=O)nc2c(F)cccc21 +O=C(NCc1ccnc(OCC(F)(F)F)c1)N1CCC(O)CC1 +Cn1c(SCC(=O)NC2CCCC2)nnc1-c1cccnc1 +Cc1nc2nc(N)nn2c(C)c1CC(=O)NCCOCC(F)(F)F +CC(=O)Nc1c(C(=O)c2ccc(F)cc2)oc2ccccc12 +Cc1cc(C)nc(-n2nc(C)c(CC(=O)NCC3CC3)c2C)n1 +O=C(NCC1CCCO1)NC1CCc2cc(F)ccc21 +Cc1cc(C(=O)OCC(=O)Nc2ccc(C)c(C)c2)c(C)o1 +O=C(NCCOCC1CCCO1)c1ccc(-n2ccnn2)cc1 +CCN(C(=O)CCC(F)(F)F)c1ccccc1S(=O)(=O)CC +CC(C)OCC(=O)Nc1cnn(CC(=O)NC2CCCC2)c1 +COCCN1CCN(C(=O)C2CC(=O)N(c3ccc(C)cc3)C2)CC1 +Cc1ccc(CNC(=O)NCC#Cc2ccccc2)s1 +OCc1ccc(CN2CC(O)CC2c2nc(-c3ccccn3)no2)o1 +O=C(Nc1ccccc1Cl)N(Cc1ccccn1)Cc1ccco1 +CCc1nnc(NC(=O)COC(=O)c2cc3ccccc3o2)s1 +CC1Cc2cc(C(=O)OCC(F)(F)F)ccc2N1S(C)(=O)=O +COc1cccc(CN2CC(c3nc(C(C)C)no3)CCC2=O)c1 +Cc1nn(C)cc1C(=O)N1CCCN2C(=O)c3ccccc3C21 +COc1cccc(-c2noc(COc3ccc(C)nc3)n2)c1 +O=C(NCc1ccc(Br)cc1)c1cn2ccccc2n1 +CC(=O)c1sc(N2CCC(O)C2)c(C#N)c1N +O=C1CCC(COC(=O)C(c2ccccc2)c2ccccc2)N1 +CC1CC(=O)Nc2ccc(Br)cc2O1 +CC1CCCN(C(=O)CSc2nncn2C)C1 +Cn1cc(NC(=O)c2cc3sccc3n2C)cn1 +CN(C(=O)CSc1ncn[nH]1)C1CCCc2ccccc21 +COc1ccc(O)c(C(=O)Nc2ccc(-n3ccnc3)cc2)c1 +Cn1cc(C(=O)NCC2CCN(C(=O)NC3CCCCC3)CC2)cn1 +Cc1c(C(=O)NCc2ccccn2)sc2nc(-c3ccccc3)cn12 +O=C(NC1CCCCC1O)c1ccc(OC(F)(F)F)cc1 +Cc1cnc2c(c1)nc(C(C)(C)C)n2CCCC#N +Cc1nn(CC(=O)Nc2ccccn2)c(=O)c2ccccc12 +CCc1nc(CNc2c(CC)cccc2CC)cs1 +Cn1ncc(NCCC(=O)N2CCCC2)c(Cl)c1=O +Nc1ccccc1N1CCN(S(=O)(=O)C(F)F)CC1 +CCN(CCOc1cccc(C)c1)C(=O)c1cccc(C(C)=O)c1 +CN(CC#CCNC(=O)Nc1ccccc1)Cc1ccccc1 +COc1cc(C=C2CCn3c2nc(=O)c2ccccc23)ccc1O +CCOc1ccc(C(=O)Nc2ccc(F)cc2)cc1OCC +COC(=O)c1cc(Cl)c(Br)cc1N +Cc1cc(C(=O)Nc2ccc(Br)c(C)c2)c(C)o1 +Cc1cc(C)n(-c2ccc(C(=O)N3CCc4ccccc43)cc2)n1 +CN(C1CCCCC1)S(=O)(=O)c1ccc(N)c(Br)c1 +O=C(c1c(F)cccc1F)N1CCN(Cc2ccc(F)cc2)CC1 +CC(C)c1cc(NC(=O)c2cccc(-c3ccoc3)c2)[nH]n1 +CC(C)(C)C(NC(=O)Nc1ccccc1Cn1cncn1)C(N)=O +CCCCNc1nnc(SCc2cc(=O)n(C)c(=O)n2C)s1 +CC(C)(Oc1ccc2c(c1)CCC2)C(=O)Nc1nccs1 +FC(F)(F)COCCSc1ncnc2nc[nH]c12 +CCCOc1cccc2c1CCNC2c1ccnc(OC)c1 +Nc1nonc1C(=O)NCCNC(=O)c1ccccc1 +CCc1nc2nnc3c(CC(=O)OC)nn(-c4ccccc4)c3n2n1 +CN(CCc1ccccc1)S(=O)(=O)c1cccc(N)c1 +CCOC(=O)CCC(C)NC(=O)c1ccc(F)cc1 +Cc1cc(C(=O)N(C)C2CCN(c3ccc(F)cc3)CC2)on1 +Cn1c(=O)n(C)c2cc(NCc3ccc(S(C)=O)cc3)ccc21 +O=C(NCCc1ccncc1)c1ccc(Cl)cc1Cl +CCCOc1ccc(-c2ccc(C(=O)NC)c(N)n2)cc1 +COc1ccc(Cl)cc1S(=O)(=O)NCc1cccnc1 +Cc1nn(C)c(C)c1C(C)NC(=O)CCNS(C)(=O)=O +Cc1csc(CNS(=O)(=O)CCn2cnc3ccccc32)n1 +CC(C)(C)OC(=O)N1CCCC1COCc1cnccn1 +CC(OC(=O)c1nccnc1N)C(=O)Nc1ccc2c(c1)CCC2 +CCOC1CCCN(C(=O)c2cn(C)nc2C(C)(C)C)C1 +CCNc1ccc(S(=O)(=O)C(F)F)cc1NC(=O)c1ccco1 +Cc1cc2nnc(SCC(=O)Nc3nccs3)n2c(C)n1 +Cc1cccnc1NC(=O)c1ccc2c(c1)CCN2 +O=C(NCCn1cccc1)NCC1CN2CCCCC2CO1 +CCOc1ccc(S(=O)(=O)Nc2cccc(O)c2)cc1C +COc1cc(C(=O)NC2CCCc3nc(C)ncc32)nn1C +O=C(c1cccc(NCc2ccccc2Cl)c1)N1CCOCC1 +Cc1nc2ccccc2n1CCNC(=O)C(C)(C)C +CCCCn1nc(C(=O)Oc2ccc3c(c2)CCC(=O)N3)ccc1=O +CN(C)C(=O)c1cc(-c2cncnc2)nc2ccccc12 +Cc1ccc(S(=O)(=O)NC(C)c2cccs2)cc1 +COc1ccc(C)cc1-n1ccn(Cc2ccccc2)c(=O)c1=O +O=c1[nH]ccc2oc(-c3cccc(C(F)(F)F)c3)cc12 +CC(C)Oc1ccccc1Cn1ccnc1S(C)(=O)=O +CCn1c(SCC(=O)Nc2c(C)cccc2C)nnc1C(C)C +COCCN1CCN(C(=O)C(C)(C)C2CCCC2)CC1=O +CCC1CN(C(=O)C2Cc3cc(F)ccc3O2)CC1N1CCOCC1 +COC(=O)c1occc1COc1ccc(Cl)cc1C(C)=O +CC(C)(C)C(NC(=O)c1cc2ccccc2oc1=O)C(N)=O +Nc1ccc(Cl)c(NC(=O)CN2CCCC2=O)c1 +CC(NS(C)(=O)=O)C(=O)Nc1ccc(N(C)C(C)C)c(F)c1 +COc1ccc(OC(C)C(=O)OCc2ccccn2)cc1 +CCN(CCC#N)S(=O)(=O)c1ccc(OC)c(Br)c1 +CCC(C)NC(=O)CCn1c(=O)[nH]c2cc(OC)c(OC)cc2c1=O +Cc1n[nH]c(C)c1CCC(=O)NC(c1ccccc1)c1ccccn1 +CN(CCc1ccccn1)C(=O)Nc1cc(Cl)ccc1N(C)C +Cc1noc(-c2ccc(-n3cnc(C(=O)NCC4CC4)c3)nc2)n1 +CCOC1C2CCC1N(C(=O)CC1Cc3ccccc3C1)CCO2 +CCCN(C)C(=O)c1ccc(-c2ccnc(N3CCCCC3)n2)cc1 +CCc1nnc(CNc2ccc(C(=O)N3CCCC(C)C3)cc2C)o1 +O=C(Nc1cccc2cccnc12)N1CCCC(CO)C1 +CN(CC(=O)Nc1cccn(C)c1=O)C(=O)OC(C)(C)C +COc1cccc2cc(C(=O)NCC3COC4(CCCCC4)O3)oc12 +COCc1nc2ccccc2n1CC(=O)Nc1ccccc1OC +O=C(Nc1cccc2cnccc12)c1cn(Cc2ccccc2)nn1 +CCCn1cc(CNc2cccnc2-n2cccn2)cn1 +CNS(=O)(=O)c1cccc(CNc2cc(C(F)(F)F)ccn2)c1 +CC(C)(C)C(O)CCNC(=O)c1cccc(C(F)(F)F)c1 +Cn1c(=O)[nH]c(=O)c2c1nc1n2CCN1Cc1ccccc1 +CC(C)Oc1ncccc1CNC(=O)c1cnccn1 +O=C(c1ccc2sncc2c1)N1CCc2ccccc21 +O=C(NCc1ccc(Oc2ccc(F)cc2)cc1)c1ccc(O)nc1 +COc1ccc(NC(=O)c2cc(C)ccc2N2CCCC2=O)cn1 +Cc1ccc2[nH]c3c(=O)n(Cc4nc(C)no4)cnc3c2c1 +COCCNC(=O)Cc1ccc(NC(=O)c2cc(C)ccc2C)cc1 +COc1ccc(CN2CNC(=Nc3nc4ccccc4o3)NC2)cc1 +COCCN(CC(=O)NC1CCCC1)C(=O)c1csnn1 +CCCCS(=O)(=O)NCc1nc(-c2ccc(F)c(C)c2)no1 +O=C(CC1CSc2nccc(=O)n21)N1CCOCC1 +COc1ccc(OC)c(CCC(=O)NCc2ncnn2C)c1 +CC(Oc1ccccc1)C(=O)Nc1nc(-c2ccccn2)cs1 +COc1ccccc1CNc1ccc(S(=O)(=O)C(C)C)nn1 +CCCOc1cc(CNC(=O)c2ccc3nnn(C)c3c2)ccn1 +Cc1cccc(NC(=O)CCOc2ccc(Cl)cc2)n1 +OCC#Cc1cc(CSc2nncs2)ccc1F +CCCCn1c(CN2CCOCC2)nc2ccccc21 +COc1ccc(C2CCCN2C(=O)c2cccnc2)cc1 +NC(=O)c1cccc(S(=O)(=O)NCc2ccco2)c1 +COCn1nc(C#N)cc1-c1ccc(N(C)C)cc1 +CC(=O)c1ccc(OC(C)C(=O)Nc2ccc(C#N)c(Cl)c2)cc1 +CNC(=O)CSc1nnc(-c2cc(C)cc(C)c2)o1 +CC(NC(=O)c1ccc[nH]1)c1cccc(N2CCCC2=O)c1 +Nc1ccc(NC(=O)CN2CCN(c3ccccc3)CC2)c(Cl)c1 +Cc1nnc(NCCc2nc3ccc(F)cc3n2C)c(C#N)c1C +O=C(Cn1ccc(=O)[nH]c1=O)Nc1ccc(F)cc1Cl +CC1CC1C(=O)NCCC(=O)N1CCCCC1CNS(C)(=O)=O +CN(Cc1ccco1)c1nc2ccccc2c2nnc(C3CC3)n12 +COCCN(C(=O)c1cccc(=O)n1C)c1ccc(C#N)cc1 +N#Cc1cn(C2CC2)c(=O)n(CCOc2ccccc2Cl)c1=O +CCCNC(=O)c1cccc(S(=O)(=O)N(C)C(C)C)c1 +Cc1noc(C)c1C(=O)N1CCCc2c(C(N)=O)cccc21 +CCn1c(C)cc(C(=O)NCc2cc(Br)cs2)c1C +CN(C)C(=O)CNc1ccccc1Cc1ccccc1 +CC(C)Cc1ccc(S(=O)(=O)N2CCCN(C(N)=O)CC2)cc1 +CCc1nc(-c2csc(S(=O)(=O)NCc3ccco3)c2)no1 +CCCS(=O)(=O)N1CCSc2ccc(N)cc21 +CCN(CC1CCOC1)C(=O)CN(CC)c1ccccc1 +Cc1c(C(N)=O)sc2ncn(CC(=O)NCc3ccco3)c(=O)c12 +Cc1ccc(NC(=O)N2CC(C)CCC2C)cc1C(=O)NC(C)C +CCOC(=O)c1nnc2nc(C(F)(F)F)nn2c1C=CN(C)C +CCOc1cc2c(cc1OCC)C(c1nc[nH]n1)NCC2 +COCCN(CC(C)C)C(=O)c1ccc(C)c(N)c1 +CC(C)C(=O)Nc1nc(CC(=O)Nc2ccc3c(c2)COC3)cs1 +O=C1CCCc2c1cc(C(=O)NCCO)c(=O)n2-c1ccccc1 +O=C(c1[nH]c2ccccc2c1Cl)N1CCCC1c1ccncc1 +CCc1ccc(C(=O)NCc2cccc(O)c2)s1 +CC1(NC(=O)NC2CCN(CC(F)(F)F)C2)Cc2ccccc2C1 +O=S(=O)(NCCCN1CCOCC1)c1cccc(Cl)c1F +Cc1cc(C2CCCN2Cc2nc(-c3ccco3)no2)on1 +Cc1nc(C)c2c(n1)CCN(C(=O)C1(C#N)CC1)CC2 +O=C(NCCCn1nc2n(c1=O)CCCC2)N(CCO)C1CC1 +Cn1c(Cn2nnc(-c3ccccc3)n2)nnc1SCC(N)=O +Cc1c(C(=O)N2CCN(CC(C)O)CC2)sc2ccsc12 +Cc1noc2ncc(NC(=O)Cn3nc(C)c4ccccc4c3=O)cc12 +Clc1cc2ncc(NC3CCCn4ncnc43)nc2cc1Cl +CN1CCN2c3ncccc3Cc3ccccc3C2C1=O +CS(=O)(=O)c1ccccc1C(=O)NCc1ccc2c(c1)OCCO2 +Cc1ccc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c(O)c1C +CCN(C(=O)CCS(=O)(=O)c1ccccc1)c1ccccc1 +O=C(CCCNC(=O)C1CC1)Nc1ccc2oc(=O)[nH]c2c1 +CNC(=O)C(NC(=O)Nc1ccc(=O)n(C)c1)c1ccccc1 +CCOC(C)C(=O)Nc1ccc2c(c1)CCN2C(=O)c1cccnc1 +CC(C)CNc1nc(-c2ccc(F)cc2F)c2c(N)n(C)nc2n1 +Cn1cc(CNc2ccc(F)cc2)c(-c2cccnc2)n1 +CCn1c(C)cc(C(=O)N2CCc3ccc(OC)cc3C2)c1C +C#CCNC(=O)C1CC(=O)N(c2ccccc2F)C1 +CCOc1ccc(NC(=O)c2cc(C)c(C)c(S(N)(=O)=O)c2)cc1 +Cn1cc(-c2nn3c(C(F)(F)F)nnc3s2)cn1 +Cc1cccc(C(=O)Nc2cc(=O)n(C)c(=O)n2C)c1 +CNC(=O)C1CCN(S(=O)(=O)c2cn[nH]c2)CC1 +COc1ccc(NC(=O)COC(=O)C2(O)CCCCC2)cc1OC +Cc1sc2ncn(CC(=O)Nc3cccc(Cl)c3)c(=O)c2c1C +c1cc(C2CC3CCN(Cc4nccs4)CC3O2)ncn1 +Cc1ccc(C(C)C)c(OCCCn2ccnc2)c1 +Cc1n[nH]c(-c2ccc(C(=O)NC3(C)Cc4ccccc4C3)cc2)n1 +CCn1c(C2CCCN2c2ncccc2C#N)nc2ccccc21 +CC(C)n1nc(-c2ccccc2)cc1NC(=O)C1CCC(=O)N1 +Cn1ccnc1SCC(=O)c1ccc(NC(=O)C(C)(C)C)cc1 +COc1ccc(NC(=O)N2CC(C)OC(C)C2)cc1OC +O=C(Cc1ccc(-n2cccn2)cc1)Nc1cccc2cnccc12 +Cc1cc(CNc2ccccc2CCO)ccc1F +CCOc1ccc(C(C)NC(=O)c2ccc(C)nc2C)cc1OC +O=C(NC1CCCCC1)c1[nH]cnc1C(=O)N1CCCC1 +COc1ccc(C(=O)N2CCc3[nH]c4ccnn4c(=O)c3C2)c(C)c1 +CC(C)C(C#N)NC(=O)c1cc2ccccc2oc1=O +Cc1noc(C)c1C(=O)NCc1cc(Br)cs1 +COC(=O)CC(NC1CC1)C(=O)c1cc(F)ccc1F +Cc1ccc(C(=O)Nc2cccc3cn[nH]c23)c(C)n1 +COc1cc(CO)cc2c1OC(c1ccccc1)C(=O)N2CCO +CNc1ncc(Br)c2ccc(N)cc12 +CCN(c1ccccc1)C(C)C(=O)c1ccc(N)cc1 +Nc1ccc2[nH]cc(C(=O)N(CCO)CCO)c2c1 +Cn1c(=O)n(C)c2cc(C(O)c3ccco3)ccc21 +COC(=O)c1ccc(S(=O)(=O)NCCO)c(N)c1 +O=C(Cc1ccc(Cl)cc1)NCCCCN1CCOCC1 +Cc1ccc(C(C)NC(=O)Cn2nnnc2C(C)C)cc1F +C=CCNC(C(=O)OCC)c1cc(F)ccc1F +O=C(NC1CCN(c2ccccc2)C1)c1ccc(OCC(F)F)nc1 +COc1ccc(F)cc1NC(=O)COc1cccc(C(N)=O)c1 +CCc1cc(CN(C)C(=O)Cn2ncc3ccccc3c2=O)on1 +Cn1cc(CNC(=O)c2cccc(Cl)c2N)cn1 +COc1ccc2oc(C)c(C(=O)N3CCOC(C)(C)C3)c2c1 +CC(C)C(=O)N(Cc1cc2ccccc2[nH]c1=O)c1ccccc1 +C=CCOC(C)C(=O)Nc1[nH]nc(C(F)(F)F)c1C +COc1ccc(Cc2ncc(N)c(=O)[nH]2)cc1OC +CN1CCOc2ccc(NC(=O)c3cnc4ccccc4n3)cc2C1=O +CC(=O)Nc1cccc(N2CCCCS2(=O)=O)c1 +CN(C)C(=O)CN1C(=O)COC2CN(Cc3ccc(F)cc3)CC21 +COC(=O)c1cccc2c(N)c(N)cc(C(=O)OC)c12 +O=C(Nc1ccc2oc(=O)[nH]c2c1)C(O)c1ccccc1Cl +Cn1cc2c(NCC(C)(C)c3ccncc3)ncnc2n1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)CCC1CCCC1 +CCN(Cc1ccc2c(c1)OCCO2)c1cccc(N)c1 +CCN(C(=O)c1cnc2[nH]ccc2c1)c1ccccc1 +CC(=O)c1ccccc1CN(C(C)C)C(F)(F)F +Cc1cc(C)n(-c2ncnc(-n3cnc4ccccc43)c2N)n1 +Cn1c(SCCCO)nc2sc3c(c2c1=O)CCC3 +O=S(=O)(Cc1cccc(F)c1)NCCc1c(F)cccc1F +COc1cccc(CC2CN(C3CCN(C(C)=O)CC3)CCO2)c1 +CN(CCNC(=O)c1cccc(-n2cccn2)n1)C(=O)OC(C)(C)C +O=C(NC1CCN(c2c(F)cccc2F)C1)c1ccccn1 +O=C(NCCO)c1nc(-c2ccccc2)n(-c2ccccc2)n1 +Cc1cc(C(=O)NCC2(N3CCOCC3)CCCCC2)on1 +COc1ccc(Cl)cc1NC(=O)N1CCCC(CNC(C)=O)C1 +Cc1cc(C(=O)Nc2cccc(NC(N)=O)c2)c(C)n1C(C)C +CCCC1CN(Cc2nc3sc(C)c(C)c3c(=O)[nH]2)CCO1 +COc1ccc(-c2nc(NC(C)C)ncc2-c2ncc[nH]2)cc1 +Clc1ccc(-c2cc(CN3CCc4cncnc4C3)on2)cc1 +CCC(=O)N1CCc2c(C(=O)NCCC(C)C)cccc21 +CCC(C)(C)NC(=O)c1nn(-c2ccccc2)c2c1CCC2 +CN(C)C(=O)c1cccc(NCC(=O)N2CCc3ccccc32)c1 +O=C1c2cccnc2CN1Cc1ccc(Cl)cc1 +Cc1[nH]c2ccccc2c1C(=O)CSc1nc(N)c(C#N)cc1C#N +COc1ccc(OC)c(-c2cn3cccc(N)c3n2)c1 +CS(=O)(=O)NC1CCN(C(=O)CCc2ccsc2)CC1 +CC1CCN(C(=O)c2cc(C3CC3)on2)c2ccccc2S1 +COc1ccc(-c2cc(-c3ccc(C)o3)nc(N)n2)cc1 +COCCOC(=O)C1=C(C)NC(=O)NC1c1ccco1 +COC(=O)C1=C(C)NC(=O)NC1c1cc(C)ccc1OC +O=C(CN1CCc2[nH]ncc2C1)NCc1ccccc1F +OCc1ccc(-c2ccc(Br)cc2F)o1 +COc1ccc(S(=O)(=O)NC2CCC(C)CC2)c(OC)c1 +COCc1ccc(CNC(=O)CNC(=O)OC)cc1 +Cc1ccc(NC(=O)NCC(=O)Nc2c(C)cccc2C)c(F)c1 +Cc1cc(=O)n(C)c(=O)n1CCCCN1CCOCC1 +Cc1nc(C(=O)NCCCN2CCOCC2)co1 +Cn1c(SCc2cccc(C#N)c2)nnc1-c1ccco1 +CCNC(=O)CCc1nc(-c2cccc(OC)c2)no1 +CC(NC(=O)Nc1ccccn1)c1ccc(F)c(Cl)c1 +CC(=O)c1ncc(Br)c2ccccc12 +CCCS(=O)(=O)N1CCC(N2CCNC2=O)CC1 +CCCNC(=O)c1ccc(S(=O)(=O)NC(C)CC)cc1 +CC1NC(=O)C2CN(S(=O)(=O)c3cccs3)CCN2C1=O +COc1cc(OC)cc(C(=O)Nc2cc(C)n(C)n2)c1 +O=C(CCc1cccc(F)c1)NC1CCCc2occc21 +CC(C)(C)CC(=O)Nc1ccc(-n2ccnc2)nc1 +Cc1ccsc1C(=O)Oc1cccc2[nH]ncc12 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(Cl)c(C#N)c2)cc1 +O=C(NCCc1csc2nc(-c3cccs3)nn12)C1CC1 +Cc1cc(C)n(CC(=O)Nc2cc(Cl)ccc2Cl)c(=O)n1 +O=C(Cc1c(F)cccc1F)OCc1cccnc1 +Nc1c(-c2cccs2)nnn1-c1ccccc1F +C=CCSc1c(CC)cnc2c1c(=O)n(C)c(=O)n2C +O=C(Cn1cnc2c([nH]c3ccccc32)c1=O)NC1CCCC1 +CNC(=O)Cc1ccc(NC(=O)C2CC(=O)N(C)C2)cc1 +COc1ccc(F)cc1NC(=O)C(C)OCC1CCCO1 +CSc1cccc(CN(C)C(=O)c2cc(C(C)C)no2)c1 +O=C(CC1NC(=O)c2ccccc2NC1=O)NC1CCCCC1 +CSc1n[nH]c2ncnc(Nc3c(C)nn(C)c3C)c12 +CCc1noc(C)c1C(=O)NCc1ccc(NC(N)=O)cc1 +COc1cc(CCCNc2ccc(C(N)=O)cc2)cc(Cl)c1O +COC(=O)C(C)NC(=O)c1ccccc1Nc1ccccc1 +CC(C)NC(=O)Nc1ccccc1NC(=O)c1csnn1 +Cn1nc(C(F)(F)F)cc1C(=O)N1CCCC1c1cccs1 +CNC(=O)C1(C)CN(C(=O)Cc2c(C)noc2C)CCO1 +Cn1nc(C2CCCN(Cc3cccc(F)c3)C2)c2nccnc21 +c1cc(Nc2nccs2)nc(C2CCCN2c2cnccn2)c1 +CC(=O)N1CCOC(CNC(=O)CSc2ccc(Cl)cc2)C1 +Fc1cc(Br)c2c(c1)C(c1nc[nH]n1)NCC2 +CC1CCN(C(=O)Cn2cnnn2)c2ccccc2S1 +CN(C)S(=O)(=O)N1CC(c2nc3c(C(N)=O)cccc3[nH]2)C1 +Cn1cccc1C(=O)OCc1cccc(C(N)=O)c1 +CSc1nc2c(cnn2-c2ccccc2)c(=O)[nH]1 +Nc1ccccc1-c1nnn(CC(=O)Nc2cccc(F)c2)n1 +Cc1cccc(C(=O)N2CC(=O)Nc3cccnc32)c1C +CCN1C(=O)c2ccc(C(=O)NC(C)C)cc2S1(=O)=O +CC(C)Cc1ccc(-c2csc(NC(=O)C3COCCO3)n2)cc1 +CSc1ccc(CCCC(=O)N2CCC(=O)CC2)cc1 +O=C(Nc1ccccc1F)c1ccn(COc2ccccc2F)n1 +CC(O)CN1CCN(C(=O)C2(c3cccc(F)c3)CCC2)CC1 +COc1nn(C)cc1C(=O)Nc1nc(-c2ccc(C#N)cc2)cs1 +CCSc1nc(=O)c2c(n1C)NC(=O)CC2c1cccc(Cl)c1 +Cc1cc(-c2csc(N(C)C)n2)c(C)n1C1CC1 +Cc1sc2ncn(CC(=O)NCC3CCCO3)c(=O)c2c1C +Cc1nnc(NC(=O)CSc2nc(C)c(C)c(=O)[nH]2)s1 +Cc1ccc(OCCNC(=O)Cc2c(C)nc3ncnn3c2C)cc1 +Cc1nn(Cc2ccccc2)c(C)c1CNc1ncnc2sccc12 +Cc1cnc2c(C(=O)N3CCCC3c3ccccn3)cnn2c1 +CC1CC(C)CN(C(=O)C(OC(=O)C2CCC2)C(C)C)C1 +CCc1nnc(CN2CCCC(c3noc(C4CC4)n3)C2)o1 +CC(C)c1nnc(CN2CCN(c3ccccc3Cl)CC2)o1 +NC(=O)Nn1ccc2c(nnc3c(-c4ccccc4)cnn32)c1=O +O=C(NC1CCCc2[nH]c(=O)ccc21)OCC(F)(F)F +COc1ccc(NC(=O)c2c[nH]c3ccc(F)cc3c2=O)cc1 +Cc1nnc(NC(C)C(=O)N2CCCCC2)c(C#N)c1C +COc1ccc(C2CN(C(=O)Cn3cnnn3)CC2NC(C)=O)cc1 +CN(C)c1cccc(CNC(=O)C2CC(=O)N(Cc3ccco3)C2)c1 +COCCCSc1ccc(NC(=O)c2ccnc(F)c2)cc1 +CC(C)CC(=O)NCC1(O)CCc2ccccc2C1 +CC(NC(=O)NCC1CCC1)c1cccc(F)c1 +CC(=O)NC1CCN(c2cc(-c3ccccc3)nc3cc(C)nn23)C1 +Cc1ccc(OCC(=O)N(C)C)c(Br)c1 +CC(=O)NC(C(=O)NCc1ccccc1F)C1CCCC1 +C#CCN(C(=O)c1c(CC)noc1C)C1CCCCC1 +O=C(NCCc1nc2c(s1)CCCC2)Nc1cn[nH]c1 +Cc1ccc(F)cc1-n1ccnc1-c1nccn1C +CCCNC(=O)c1nn(-c2ccc(F)cc2)c(OCC)cc1=O +Cc1cc(C(=O)N(C)Cc2cccc(Cl)c2)c(C)o1 +Cc1ccc(C(=O)OCC(=O)Nc2ccc3c(c2)OCO3)s1 +COC(=O)c1c(C)c2c(C(=O)OC)cc3cccc1n32 +COc1cc(C)ccc1OC(=O)Cc1c(F)cccc1F +COc1ccc(C2Cc3[nH]nc(C)c3C(O)C2)cc1OC +CSc1ccc(CNc2cccc(C(=O)NCCO)c2)cc1 +CCn1cc(C(=O)NCCCc2ccco2)c(=O)c2ccc(C)nc21 +Cc1nc(C2CCN(C(=O)NC3CCCCC3)CC2)n[nH]1 +Cc1nc(CNC(=O)Nc2ccc(F)cc2C#N)c(C)s1 +COc1ccccc1CNC(=O)c1cc2c(nc1N)CCC2 +COc1ccc(-c2csc(NC(=O)c3ccoc3)n2)c(OC)c1 +CCOC(=O)CN(C)C(=O)c1ccc2c(c1)CCO2 +CCOC(=O)CN1CCN(c2ncc(C#N)c(N)n2)CC1 +CCNC(=O)c1onc(-c2ccc(Cl)cc2)c1N +Cc1ccc(C(=O)N2CCC3OCCCC3(COCC3CC3)C2)cn1 +O=C(C1CCOCC1)N1CCC2C1CCN2c1ncccn1 +CCCc1nn(Cc2ccn(C(C)C)n2)c(=O)o1 +CCCCc1ccc(C(=O)CCN2CCOCC2)cc1 +CC(=O)N1CCN(c2cc(N)ccc2Cl)CC1 +CCc1noc(CN(C)C(=O)Cc2c(CC)noc2CC)n1 +O=S(=O)(c1ccccc1)N1CCC(CO)CC1 +Cc1nnc2n1CC(NC(=O)c1csc(-c3ncccn3)n1)CC2 +Cn1cccc1CN1CCN(Cc2ccc(Cl)cc2)C(=O)C1 +N#CCCN1CCN(C(=O)COc2ccccc2)CC1 +CC(=O)N1CCCCC1c1nc(-c2ccccc2)no1 +Cc1ccc(NC(=O)N(C)Cc2cc(C)no2)c(C)c1 +COCn1c(-c2cccc(F)c2)nc2c(N)cccc21 +CS(=O)(=O)N1CCc2cc(C(=O)N(CC3CC3)CC3CC3)ccc21 +CC1CCCC(NC(=O)NC(C)C(=O)N(C)C)C1 +COC(=O)C1C2C=CC3(CN(c4ccc(Cl)cc4)C(=O)C13)O2 +CCCOC(=O)c1cc(-c2ccc(O)c3ncccc23)nn1C +CC(=O)Nc1cccc(C(=O)OCC(=O)NCc2cccc(C)c2)c1 +CN(C(=O)CCNC(=O)c1ccoc1)C1(C#N)CCC1 +NC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccc2nccn2c1 +COc1ccc2c(c1)C(C(CO)c1ccccc1)NCC2 +CCOC(=O)c1cnc(N2CCC(CO)CC2)nc1 +CC(C)CNC(=O)C(NC(=O)c1cnn2c1OCCC2)C(C)C +FC(F)(F)c1cc(NCC2CCCCO2)n2ncnc2n1 +c1ccc(OC2CN(Cc3ccco3)C3CCCOC23)nc1 +N#Cc1ccc(-c2csc(C(C#N)C(=O)C3CCOCC3)n2)cc1 +CC=CCOC1CCCN(C(=O)CCc2ccccc2)C1 +CCc1nc2cc3c(cc2n1CC(=O)N1CCCC1)OCCO3 +CN1CCN(C(=O)COc2ccc(F)cc2F)CC1 +O=C(CCNC(=O)NCC(O)c1ccco1)NC1CCCCC1 +CCNS(=O)(=O)c1cc(-c2onc(C)c2C)ccc1OC +COc1c(CNC(=O)c2ccc(C)nc2)c(C)nn1C +CN(CC(=O)NC1(C#N)CCCCC1)Cc1nccn1C(F)F +N#Cc1ccc(OCCSc2n[nH]c(=O)n2CC2CCCO2)cc1 +CC(O)(CNS(=O)(=O)c1cccc(Cl)c1)C1CC1 +O=C(Nc1ccccc1OCC1CCCCO1)c1cc[nH]n1 +CC(C)=CC1C(C(=O)N(C)Cc2cc(C)on2)C1(C)C +O=S(=O)(NCCn1ccc(-c2ccncc2)n1)c1ccc(F)cc1 +CC(CO)C(C)NC(=O)NCC1CN2CCCCC2CO1 +Cc1occc1-c1nnc(SCc2ccccc2)o1 +O=C(NCCC1=CCOCC1)c1c(F)c(F)cc(F)c1F +Cc1ccc(-c2nnco2)cc1NCc1cc(F)cc2cccnc12 +CC(C)COC(=O)n1c(=O)oc2cc(Cl)ccc21 +Cn1c(CN2CCN(c3ccccc3Cl)CC2)cc(=O)n(C)c1=O +Cc1ccccc1OCC(=O)OCC(=O)NC1CC1 +O=C(c1ccc(O)cc1)N1CCN(C(=O)C2CCCO2)CC1 +C=CCNC(=O)CCNS(=O)(=O)c1cccnc1 +COc1ccccc1OCC(=O)Nc1ccc2c(c1)C(=O)NCC2 +COc1ccc(OC)c2c1CN(Cc1nc3ccccc3o1)CC2O +CCSc1cc(C(=O)NC2=NC(=O)N(C)CC2)ccn1 +COc1ccc(NC(=O)NC(C2CC2)C2CC2)cc1OC +CCn1c(SCCCC#N)nc2cc(S(N)(=O)=O)ccc21 +Cc1nn(C)cc1S(=O)(=O)Nc1cccnc1 +CC(C(=O)Nc1cccc(-n2cnnn2)c1)c1ccsc1 +CCc1ccccc1CNC(=O)NC(C)C1CCCO1 +CCOCC(=O)Nc1cc(C(F)(F)F)ccc1OCC +NC(=O)c1ccccc1OCc1cc(=O)n2ccccc2n1 +c1nc(N(CC2CCCO2)C2CCCC2)c2cn[nH]c2n1 +CC(=O)N1CCc2cc(NC(=O)CNc3ccc(C)cc3C)ccc21 +NS(=O)(=O)Cc1ccc(NS(=O)(=O)c2cn[nH]c2)cc1 +O=C(c1ccc(F)c(S(=O)(=O)NC2CC2)c1)N1CCCCCC1 +CC(=O)c1cccc(NC(=O)N2CCC(c3cc(N)on3)CC2)c1 +Cn1ccc(NC(=O)Cc2noc3ccccc23)n1 +CCOc1ccc(Nc2ccc(C#N)cn2)cc1F +COC(=O)C1CCCCCC1NC(=O)CCNC(=O)c1ccco1 +CN1CCN(C(=O)c2onc(-c3ccccc3F)c2N)CC1 +CCOC(=O)C1=C(COC(=O)c2ccccc2F)NC(=O)NC1C +Cc1nc(CNc2cc(Cl)ccc2-n2cccn2)cs1 +O=C(CSc1nnc(C2CC2)n1Cc1ccco1)c1ccccc1 +Cc1cc(C(=O)NCc2ccccc2F)nc(N)n1 +COc1cc2c(cc1NC(=O)c1cc(C)on1)oc1ccccc12 +CC(C)(C)NC(=O)C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +O=C(CN1CCN(c2ccc(F)c(F)c2)C1=O)N1CCOCC1 +CN(C(=O)c1c(-c2cccs2)cnnc1N)c1ccccc1 +O=C1c2cc(Br)ccc2OCC12CC2 +CN(Cc1ccccc1)C(=O)CNc1cccc(Cl)c1 +CCc1noc(-c2ccc(-n3ncc(C(=O)NC)c3C)nc2)n1 +CC(c1cccc(O)c1)N(C)Cc1cnc(-c2cccnc2)s1 +CCCCC(=O)N(C)C(C#N)c1ccc(OCC)cc1 +CCC(C)NC(=O)C(C)NC(=O)Nc1cc(OC)c(OC)cc1C +CC(=O)C(Cc1ccccc1)NC(=O)CSc1ccc(F)c(F)c1 +COc1ccc(C)cc1-n1nnnc1SCC(=O)N1CCCC1 +CCC(C)n1ncc(C(=O)N2CCOCC2C)c1C1CC1 +CCn1cc(CO)c2cc(Br)ccc21 +CCOC(=O)c1cc(-c2cc(OC)ccc2OC)no1 +N#CCc1ccc(-n2nc(-c3ccc(O)cc3)c3c2CCNC3)cc1 +Cc1ccccc1CN(C)C(=O)c1cccc(N(C)C)c1 +COC(C(=O)Nc1ccc(CNC(N)=O)cc1)c1ccccc1 +C#CCOc1ccccc1CN(C)C(=O)c1cc(C(C)C)n(C)n1 +Cc1cc(NC(=O)CNc2cccc(OCC3CCCO3)c2)n(C)n1 +O=C(CC1CCOc2ccccc21)Oc1cccc(-n2cccn2)c1 +Cc1ccc(N2CC(NS(=O)(=O)c3cccs3)CC2=O)cc1 +Cc1ccc(NC(=O)CN2CCN(C(=O)c3cccnc3)CC2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)NCc1ccncc1 +CCOC1CCCN(C(=O)Cn2c(=O)[nH]c3ccccc32)C1 +COCC(=O)NCCn1nc(C(F)(F)F)cc1C1CC1 +CNC(=O)CSc1nnc(C)c2cnn(-c3ccc(F)cc3)c12 +Clc1cccc(OCCc2nc3c(s2)CCN3)c1 +NC(=O)CCOc1ccccc1NC(=O)Cc1cn2ccsc2n1 +COCCNC(=O)Nc1cccc(C(F)(F)F)c1 +CC12CCC(C(=O)Nc3ccc(F)cc3F)(CC1=O)C2(C)C +Clc1ccc2c(c1)CN(CC1CCCO1)CC2 +CC(=O)N1CCCN(C(=O)c2cc(C)on2)CC1 +CCOC(=O)N1CCN(C(=O)c2cc(Cl)cc(Cl)c2)CC1 +Cc1cc(C)n(-c2ccc(C(=O)NC(C)c3ccccc3)nn2)n1 +Cc1cccc(N2CCN(CC(=O)NCc3ccccc3F)CC2)c1 +CCC1CCCN(C(=O)C2COc3ccc(F)cc3C2)C1 +O=S(=O)(c1ccc(NCC(F)(F)F)cc1)C(F)F +COCCN(Cc1ccccn1)C(=O)c1cc(F)c(C)cc1F +O=C(NCc1ccccc1)C1CCCN1C(=O)c1cc2cccnn2n1 +Nc1nc(CNc2cc(-c3ccc(F)cc3)nc3ccnn23)n[nH]1 +O=C(CCC(=O)c1ccc(F)c(F)c1)NCCc1ccccc1F +Cc1ccc(NC(=O)CS(=O)(=O)c2nncn2C)cc1Cl +O=C(c1nc2ccccc2s1)N1CCOCC1CO +COCCn1cc(C(=O)NCc2ccc(F)cc2)c2n[nH]c(=O)c-2c1 +COc1ccc(Cl)c(NC=Cc2nnnn2-c2ccc(C)cc2)c1 +COc1ccc(C(=O)N2CCC(NC(=O)C(C)C)CC2)c(OC)c1 +Cc1ccc(OC2CCN(C(=O)C3CCC3)CC2)nn1 +O=C(CCCOc1ccccc1)Nc1ccc2c(c1)COC2 +CCCC(=O)N1CCc2c(c(C(=O)NCc3ccccc3)nn2C)C1 +COc1ccc(Cl)cc1NC(=O)Cc1csc(NC(C)=O)n1 +CCC(CO)NC(=O)c1cn(CC)c2cccc(N)c2c1=O +CNC(=O)CSc1nnc(-c2ccc(OC)cc2)o1 +CC(C)CC1COCCN1C(=O)Nc1cccc(N2CCCC2=O)c1 +Cc1nn(C)c(C)c1NC(C)c1cccc(C#N)c1 +Nc1c(NC2CCCCC2)ncnc1N1CCCCCC1 +CC(C)(C)OC(=O)Nc1cccc(COc2ccc(C(N)=O)cc2)c1 +COCCNC(=O)Nc1ccc(CC(=O)NC2CC2)cc1 +Cc1ccc(CC(C)N(C)Cc2cnc(N3CCOCC3)nc2)cc1 +CCn1ncc2cc(C(=O)N(C)c3ccccc3)c(N)nc21 +CC1=Nc2nc(-c3cccs3)nn2C(c2cccs2)C1C(N)=O +Cc1nc2c3c4c(sc3nc(C)n2n1)CN(Cc1ccccc1)CC4 +CC(O)CN1CCN(CC(=O)Nc2sccc2C#N)CC1C +Cn1ncc(C(=O)NCc2ccc(F)cc2)c1-n1cccc1 +CCCc1cc(CNC(=O)c2c(-c3ccncc3)noc2C)on1 +Cc1nc(NC(=O)Nc2ccccc2)sc1C(=O)N(C)C +N#CC1CCCN(S(=O)(=O)CCCc2ccccc2)C1 +NC(=O)c1ccccc1NCc1cn2cc(Cl)ccc2n1 +O=C(NC1CCCOc2ccccc21)N1CCC(O)(C(F)(F)F)C1 +CCS(=O)(=O)N1CCN(C(=O)c2ccc(C)cc2O)CC1 +Cc1cc2ncc(C(=O)N(C)c3ccccc3)c(C)n2n1 +Cc1cc(S(=O)(=O)NC(C)Cn2cncn2)c(C)s1 +Cc1nnc(NC(=O)NCc2cn3c(C)c(C)sc3n2)s1 +CCNC(=O)C(C)n1c2ccccc2c2cnn(C)c(=O)c21 +CC(=O)c1cc(-c2ccccc2)n(CC(=O)N2CCCC2)c1C +CC(C)c1nnc(-c2cc3ccccc3n2CC#N)o1 +CCOC(=O)C(C)N1CCN(CC(=O)Nc2cc(C)on2)CC1 +O=C(Nc1ccc(Cc2ccncc2)cc1)c1nc2ncccn2n1 +CC(C)n1ccc(C(=O)Nc2ccc(Cl)cc2C(=O)NC2CC2)n1 +Cc1cc(-c2ccccc2)nc(-n2ncc(C#N)c2N)n1 +COc1cc(NC(C)C(=O)Nc2ccc(C(N)=O)cc2)cc(OC)c1 +Cc1ccccc1CNC(=O)c1c(C)oc(C)c1S(N)(=O)=O +COc1cc(C#N)ccc1OCCn1c(-c2ncccn2)noc1=O +Cc1n[nH]cc1NC(=O)c1ccc(Br)cc1F +O=C(NCCn1nc(-c2ccncc2)cc1C1CC1)C1CCC1 +COc1cccc(CCC2CCCN(C(=O)c3ccoc3C)C2)c1 +Cn1cccc1C(=O)Cn1cc(S(=O)(=O)N2CCCC2)ccc1=O +C#CCNC(C(=O)Nc1cccc(OC)c1)c1ccccc1 +C=CCn1nc2c(C)c(C)nc(-c3cccnc3)n2c1=O +Cn1cc(C(=O)N2CCC(C)(C)C2)c(C(C)(C)C)n1 +Cc1ccc(F)cc1NC(=O)c1cccc(C(=O)N(C)C)c1 +CCN(CC)S(=O)(=O)c1ccc2[nH]c(=O)c3ccccc3c2c1 +O=C1CCN(c2ncnc3sc4c(c23)CCCC4)CCN1 +CCn1cc(-c2cc(-c3cc(OC)ccc3OC)nc(N)c2C#N)cn1 +C=CCOC(=O)C1=C(C)NC(=O)NC1c1ccc(OCC)cc1 +CSc1ccccc1NC(=O)c1ccc(-n2cnnn2)cc1 +CCCCC(CC)C(=O)N1CCC(C(N)=O)c2ccccc21 +CC(C)CCCOc1cc2c(cc1N)NC(=O)CC2 +CCc1nnc2n1CC(CNc1ncnc3c1cnn3C)CC2 +CC1CN(CCNC(=O)c2cnc(-c3ccccc3)s2)CC(C)O1 +COc1cc(NC(=O)c2cc(C)c(C)s2)cc(OC)c1OC +O=C(OC1CCOC1=O)c1nn(-c2ccc(F)cc2)c2c1CCC2 +O=C(NCCOc1ccc2c(c1)OCO2)Nc1ccccn1 +COc1ccc(NC(=O)CCc2ccc(C)cc2)cc1N +Cc1ccn2c(CN3CCOC4(CCC4)C3)cnc2c1 +Cc1cc(C)n(-c2nnc(SCC(=O)NC(C)C(C)C)n2N)n1 +Cc1ncsc1CN1CC2COCC2(COc2ncccc2F)C1 +Cc1c(C(=O)OC(C)C(=O)Nc2ncnc3nc[nH]c23)cnn1C +CCCCNC(=O)c1coc(COc2ccccc2F)n1 +CC(=O)Nc1cccc(NC(=O)C2CCOCC2)c1 +CCS(=O)(=O)c1ccc(NC(=O)NCc2ccc(F)cc2)cc1 +Cc1cc(-c2nnc(CN3CCOC4(CCCCCC4)C3)o2)c(C)o1 +CCOC(=O)NC1CCCN(C(=O)c2cccc(OC)c2F)C1 +NC(=O)C1Cc2ccccc2CN1C(=O)Cc1ccc(F)cc1F +COc1ccc(S(=O)(=O)NCC(C)O)cc1Br +Cc1cc(C(=O)Nc2ccc(CN3CCOCC3)c(Cl)c2)n(C)n1 +CC(C)C(NC(=O)c1cnn(C)c1)c1ccc(F)cc1 +CC(O)CC1COCCN1C(=O)NCC(C)c1ccc(F)cc1F +CC(C)(C)C(=O)Nc1ccccc1-c1nc2ccccc2[nH]c1=O +CCCCC(=O)Nc1ccc(-c2ccc(S(=O)(=O)CC)nn2)cc1 +Cc1ccc2cccc(Oc3ncnc(Nc4ccccn4)c3N)c2n1 +CC(C)(C)NC(=O)COC(=O)CCc1nc2ccccc2s1 +Cc1nnc(SCC(=O)Nc2nonc2C)s1 +N#CCOc1ccc(-c2csc(-c3ccncc3)n2)cc1N +Cc1c(C(=O)Nc2nccs2)sc2nc(-c3ccccc3)cn12 +CCC(=O)N1c2ccc(S(=O)(=O)N3CCCC3)cc2CC1C +CCOc1cc(-c2nc(COc3ccc(OC)cc3)n[nH]2)ccc1O +C#CCOc1ccc(CCNC(=O)Nc2c(C)noc2CC)cc1 +COCC(C)NC(=O)c1cn(Cc2ccccc2C)nn1 +COCc1nn(CCc2scnc2C)c(=O)o1 +CC(=O)c1ccc(NC(=O)C2CC(=O)Nc3ccccc32)cc1 +Cc1cccc(Cn2nc(C)cc2NC(=O)C2CCC(O)CC2)c1 +Cc1ccc(N2CCC3OCCN(CC4CC4)C3CC2)nn1 +COc1ccc(OC)c(CCC(=O)NCCO)c1 +Cc1nc(C2CN(Cc3ccc(Br)cc3)CCO2)no1 +Cc1noc(C)c1S(=O)(=O)Nc1ccccc1C(N)=O +O=C(NCc1ccc(Cl)cc1)Nc1ccncc1 +CCOC(=O)c1ccc(NC(=O)N2CCN(C)c3ncccc32)cc1 +Cc1cc(OCc2ccc3c(c2)OCO3)nc(N2CCCC2)n1 +CC1(C(=O)Nc2ccc(Cl)cn2)Sc2ccccc2NC1=O +Cc1nnsc1C(=O)OCc1ccc(C#N)cc1 +CCn1ccnc1N1CCN(C(=O)c2ccc3ccccc3c2)CC1 +CCCNC(=O)CNc1cccc(NC(=O)C(C)(C)C)c1 +Cc1ccc(S(=O)(=O)NC2(C)CCCC2)cc1F +COc1cccc(OCC(=O)N(C)c2cccc3ncccc23)c1 +O=C(CCCc1ccccc1)N1CCC(Nc2cccnc2)C1 +COCCCNC(=O)c1cc2ccccc2c(N)n1 +CN(CCN1CCCC1=O)C(=O)c1ccc(Cl)c(Cl)c1 +CN(CC(N)=O)C(=O)c1nc(-c2cccs2)n(-c2ccccc2)n1 +CC(O)C(NC(=O)CCNC(=O)c1ccc(F)cc1)C(N)=O +COc1ccc(NC(=O)NCc2ncn(C)n2)c(C)n1 +CC(=O)N1CCc2cc(NC(=O)NCc3ccccc3Cl)ccc21 +O=C(NC1CCN(c2ccccc2)C1=O)c1ccc2c(c1)OCO2 +Cc1ccc(N2CCN(C(=O)c3ccc(C)c(C)c3)CC2)nn1 +CC(NC(=O)c1ccc[nH]c1=O)c1ccc2c(c1)NC(=O)CO2 +CCCC(=O)N1CCCCC1C(=O)Nc1cc(OC)ccn1 +COc1cccc(C(=O)N2CCN(C(=O)OCC(C)C)CC2)c1 +CN(Cc1cnn(-c2ccccc2)c1)Cc1cccc2nonc12 +Cc1ccc(C)c(OCC(=O)NCc2ccccn2)c1 +Cc1nnc(SCC2CCCC2)n1CC(N)=O +C=CCN(CC=C)C(=O)CSc1ncnc2sc(C)c(C)c12 +Cc1ccc(NC(=O)NCc2nc3ccccc3[nH]2)cc1Cl +CCn1c(=O)c(NCc2cc(F)ccc2F)nc2ccncc21 +Cc1ccc(N2CCC(C(=O)N3CCCC(CO)C3)C2=O)cc1 +CCOC(=O)c1ccccc1NC(=O)Cn1nnc(C#N)c1C +Cc1ccn(-c2ccc(C(=O)NC3CCc4nnc(C)n4C3)cc2)n1 +Cn1cccc1CN1CCN(c2cnn3cnnc3c2)CC1 +Cc1ncc(C(=O)NC(C(=O)Nc2cc[nH]n2)c2ccccc2)s1 +COc1ccc(CNC(=O)C2(c3cccc(F)c3)CCOCC2)cc1 +O=C1CCN(C2COc3ccc(F)cc3C2O)CC1 +O=C(NCc1cccc(F)c1)c1ccc2ccccc2n1 +CCn1cc2c(n1)CN(S(=O)(=O)N(C)C)CC2COC +COC(=O)C1(N(C)C(=O)C(C)c2c(C)noc2C)CCCCC1 +C=CCc1ccc(OC(=O)Cn2ccc(=O)n(C)c2=O)c(OC)c1 +O=C(NCc1ccc(-n2cccn2)nc1)NCc1ccccc1Cl +COC1(C)CCC2(O)C(=O)OC3C(O)COC32O1 +Clc1ccc(-c2nnn(Cc3nnnn3-c3ccccc3)n2)cc1 +O=C(Cc1ccc(Cl)cc1)Nc1ccc(CO)cn1 +CC1CN(C(=O)NCC(=O)N2CCCC2)c2ccccc21 +c1ccc(-c2ccc3c(c2)C(Cn2cnnn2)NCC3)nc1 +O=C(Cc1csc(-c2ccsc2)n1)NCc1ccco1 +CCn1cc(C(=O)N(C)Cc2ccc(C(=O)NC)cc2)cn1 +CCCn1cc(NCc2cc(OC)c(OC)cc2C)cn1 +O=C(CCC(=O)c1ccccc1)OCc1nc2ccccc2o1 +O=C(CN1CCc2ccccc21)NC1=CC2=CC=NC2C=C1 +COC(=O)C(C)NC(=O)N1CCC(C(N)=O)CC1 +Cc1cccc(C(=O)NCCC(=O)Nc2c(C)cccc2C)c1 +CC(NC(=O)NCc1ncn(C)n1)c1ccccc1C(F)(F)F +COc1ccccc1C(C)N(C)Cc1cnc2cnccn12 +COC(=O)c1ccc(C2CC(O)=Nc3c2ncn3-c2cccnc2)cc1 +N#Cc1c(Cn2ncc3ccccc3c2=O)cn2ccccc12 +CNC(=O)NCC(=O)Nc1ccc(C)cc1OCC(F)(F)F +O=C(NC(C1CC1)C1CC1)C1CCN(c2ccc3nncn3n2)CC1 +CC1Cc2cccc3c(=O)c(C(=O)NC4CCCCCC4)cn1c23 +CC1CC(Nc2ncnc3c2cnn3C)CC(C)(C)C1 +CC(=O)Nc1ccc(NCc2noc(-c3cccs3)n2)c(Cl)c1 +O=C(NCCCn1nc(C(F)(F)F)cc1C1CC1)c1cnccn1 +COc1cc(-c2c(C)n[nH]c2C)cc(C#N)c1OC +O=C(Nc1cnn(-c2ccccc2)c1)N1CCCC2CCCC21 +C#CCN(Cc1ccco1)C(=O)Cc1c(C)nc2cc(=O)[nH]n2c1C +CNC(=O)c1ccc(C)c(NC(=O)NCCO)c1 +O=C(Nc1nncs1)c1ccc(COc2ccc3c(c2)CCC3)o1 +O=C(CCc1ccc(-c2ccccc2)o1)Nc1ccncc1 +COc1cc(C(C)=O)ccc1OC(=O)Cc1cccc(F)c1 +O=C(NCc1nc2ccccc2[nH]1)c1cccc(-n2cnnn2)c1 +O=C(c1ccc(F)cc1)N1CCC(Oc2cnccn2)CC1 +CCn1nnnc1COc1cccc(C(=O)Nc2cccc(F)c2)c1 +CC(=O)N1CCc2cc(S(=O)(=O)NC(C)c3ccncc3)ccc21 +O=C(OCCc1cn[nH]c1)c1cnc(C2CCCO2)s1 +CN(CC1CN(Cc2ccccc2)CCO1)c1cccnn1 +Cc1noc(-c2ccc(=O)n(Cc3c(C)noc3C)c2)n1 +NC(=O)c1ccc(N2CCCC2)c(NC(=O)c2ccccc2)c1 +O=C(NCCN1CCCC1=O)c1cccc(-c2ccccc2F)c1 +CC(=O)c1ccc(S(=O)(=O)N(C)CCC(F)(F)F)cc1 +CC1CC1c1ccc(CN2CCOC3(CCC3)C2)o1 +Cn1c(=O)n(C)c2cc(C(=O)C3CCCC3)ccc21 +CCC1CCCN(C(=O)C(C)OCc2cccc(OC)c2)C1 +CSc1n[nH]c2ncnc(NCc3cccc(Cl)c3)c12 +Cc1csc(C2CCN(C(=O)c3ccc(C)c(C)c3)CC2)n1 +COC(=O)CCC(N)C(=O)c1cc(C)c(OC)cc1C +NC(=O)Cn1cc(NC(=O)Cc2ccc(Cl)cc2)cn1 +NC(=O)N1CCCC1C(=O)Nc1ccc(OC(F)F)c(Cl)c1 +Cc1c(C(=O)Nc2ccccc2)cnc2nc(-c3ccncc3)nn12 +O=C1CN(Cc2nc3sc(-c4ccccc4)cc3c(=O)[nH]2)CCN1 +Cn1cccc1CN1CCN(C(=O)Cc2ccccc2F)CC1 +Cn1cc(CCNC(=O)NCc2ccc(C(N)=O)cc2)cn1 +Cn1c(=O)oc2cc(-c3noc(-c4ccoc4)n3)ccc21 +CC(C)c1ccc(NC(=O)c2ccncc2)c(N)c1 +O=C(Nc1ccc(F)cc1)c1cc(=O)[nH]c2ccccc12 +CCC(c1ccc(F)cc1)N1CCN(C(=O)c2ccc(O)cc2)CC1 +COC(=O)CCNC(=O)Cc1ccc(Br)cc1 +COc1ncnc2c1CCN(C(=O)c1cccn1C)CC2 +Cc1ccc(-n2cc(C(=O)OCCC(C)C)nn2)cc1 +CCCc1nnsc1C(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1cnccc1CCNC(=O)NCc1ccnc(OC2CCC2)c1 +CCC(C)N(C)C(=O)c1cc(S(=O)(=O)N2CCOCC2)c[nH]1 +CCc1nnnn1CC(=O)Nc1ccc(C(=O)OC)cc1 +Cc1ccc(S(=O)C(C)C(=O)NCc2ccc(F)cc2)nc1 +CC1CCCCN1C(=O)Nc1ccnn1C(C)C +CCCNC(=O)NC(CC)c1ccc2c(c1)OCCO2 +O=c1c(-c2nc(-c3cccc(F)c3)no2)c[nH]c2ccc(F)cc12 +Cc1ccccc1CC(=O)Nc1ccnn1CC(C)C +CCCn1cnc2sc(C(=O)N3CCCC(C)C3)c(C)c2c1=O +COc1ccc(C(C)=O)c(OCc2csc(-c3cnn(C)c3)n2)c1 +Cc1cc2c(SCC(=O)NCC3CCC3)ncnc2s1 +COc1ccc(-c2nnsc2C(=O)NCCC(C)C)cc1 +COC(=O)c1ccncc1C(=O)OC(C)C(=O)N(C)C +CCN(CC)c1ncnc(NCCc2cccs2)c1N +CN(C(=O)COc1ccc(C#N)cc1)C1(C#N)CCCCC1 +NC(=O)C1CCN(C(=O)c2cc(F)ccc2F)CC1 +O=C(Cc1c[nH]c2ccccc12)NC1CC(=O)N(C2CC2)C1 +N#Cc1cccc(OCC2COC3CN(Cc4cccs4)CC23)c1 +CCOC(=O)N1CCc2nc(NC(=O)c3ccn(CC)n3)sc2C1 +CCCn1c(C)nnc1SCC(=O)Nc1ccc(F)cc1F +CC(C)N(C)C(=O)NC1CCC2(CC1)OCCO2 +Cc1nc(C(C)C)ncc1C(=O)N1CCC2(CCCN(C)C2=O)C1 +O=C(Cc1ccc2ccccc2n1)c1ccsc1 +CC(C)CCN(CCC#N)C(=O)Nc1cnn(-c2ccccc2F)c1 +Cc1cccc(C(C)CNC(=O)c2cccc(C(=O)N(C)C)c2)c1 +CC1Cc2cc(S(N)(=O)=O)ccc2N1C(=O)COC(=O)C1CC1 +O=C(CCNS(=O)(=O)c1ccccc1)Nc1nc2ccccc2[nH]1 +NC(=O)c1ccsc1NC(=O)COC(=O)Cc1ccc(F)cc1 +COc1ccccc1C1Nc2ccccc2C(=O)N1CC1CCCO1 +Cc1ccc(C(O)C(C)C(=O)c2ccccc2)cc1 +Cc1cccc(NC(=O)CSc2cc(C)[nH]c(=O)n2)c1 +Cc1ccc(OCC(C)NS(=O)(=O)c2c(C)nn(C)c2C)cc1 +Nc1cc(=O)[nH]c(SCC(=O)NCc2cccc(Cl)c2)n1 +COc1ccc(C(N)=O)cc1S(=O)(=O)N1CCCCCC1 +COc1ccc(C2=CCN(C(=O)NCCc3cnn(C)c3)CC2)cc1 +O=C(c1c(F)cc(Br)cc1F)N1CCc2[nH]ncc2C1 +O=C(CCNC(=O)c1ccccc1Cl)Nc1ccccc1F +Cc1cc(C(=O)Nc2ccc3c(c2)OCCCO3)ccc1N +Cc1ccn(C(=O)COc2ccccc2C(C)C)n1 +O=S(=O)(NCc1ccco1)c1ccc2ccccc2c1 +Cc1c(Br)c(C(=O)Nc2cccc3cccnc23)nn1C +CC(C)n1ccnc(Oc2ccc(Cl)cc2N)c1=O +COc1cc(OC)cc(C(=O)Nc2nnc(-c3cccc(C)c3)o2)c1 +CCOC(=O)C1CCN(C(=O)CN2CCCc3ccccc32)CC1 +Cc1ccccc1CC(=O)NCc1ccc(-n2ccnc2C)cc1 +CCc1ncc2c(N3CCN(C(C)=O)CC3)nccn12 +O=C(c1cc2ccccn2c1)N1CCN(c2ccc(Cl)cc2)CC1 +Cc1cc(C)cc(N2CC(C(=O)Nc3cc(C)ccn3)CC2=O)c1 +Cc1ccnc(Nc2ncnc(Nc3nc(C)c(C)s3)c2N)c1 +Cc1cc(OC(C)CC(=O)N2CCNCC2)cc(C)c1Cl +COCCCNC(=O)c1c(-c2ccccc2Cl)noc1C +Cc1ccc(C(=O)C(C)OC(=O)c2c(C)noc2C)cc1C +CC(=O)Nc1cc(C(=O)NCc2ccco2)ccc1F +CC(C)(C)c1cc(-c2cccn2-c2ncccn2)c(C#N)c(N)n1 +O=C(Cc1cccc(O)c1)Nc1ccc(CN2CCOCC2)cn1 +Cc1ccc(S(=O)(=O)Nc2ccc(C)c(-n3cnnn3)c2)cc1 +Cc1csc(=O)n1CC(=O)NC1CCCCC1C(F)(F)F +CCc1c(C(=O)OCC(F)(F)F)cnn1-c1ccc(F)cc1 +Nc1nc(SCCN2c3cccc4cccc(c34)S2(=O)=O)n[nH]1 +CN(C)c1ccc(C(=O)OCC(=O)c2ccc3c(c2)OCO3)cn1 +O=C(Nc1ccccc1)N1CCn2cc(C(=O)N3CCCC3)nc2C1 +Cc1cc(Oc2ncccn2)ccc1NC(=O)COC1CCCC1 +CC(=O)N1CCN(C(=O)CCNC(=O)OC(C)(C)C)CC1 +O=C(Cn1c(=O)c2cccn2c2ccc(F)cc21)NC1CC1 +Cc1ccc(C(=O)NC(C)c2ccccc2NS(C)(=O)=O)cc1 +Cn1cnc(CNC(=O)Nc2cccc(-n3ccnn3)c2)n1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)N(Cc1ccc(F)cc1)C1CC1 +O=C(Nc1cccc(N2CCCCCC2)c1)N1CCCC(O)C1 +CC(CC#N)N(C)S(=O)(=O)c1cccc(Br)c1 +CC=CCn1c(=O)c2c(nc3n(CC)c(C)cn23)n(C)c1=O +CCn1cc(NCc2ccnn2C2CCCC2)cn1 +CC(=O)Nc1cccc(Nc2cc(F)ccc2F)c1 +CCOC(=O)c1cccnc1N1CCCC(c2nc(C)no2)C1 +CCC(C)(C)OCc1ccc(F)cc1C#CCO +CC(=O)NCCn1cc2c(n1)C1CN(C(=O)C(C)(C)C)CC1CC2 +CCCC(NS(=O)(=O)CC(C)C)c1nnc2ccccn12 +COC(=O)CCCNc1nncc(-c2ccc3ccccc3c2)n1 +O=C(Nc1ccncc1)c1cccc(S(=O)(=O)NC2CC2)c1 +CC1(C)Cc2nc3sc4c(N5CCCC5)nnnc4c3cc2CO1 +Cc1ccc(-c2ccc(=O)n(CC(=O)Nc3ccccc3)n2)c(C)c1 +CC1CCCC(CC(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)C1 +CC(=O)c1c(C)nc(C)nc1SCC(=O)Nc1c(C)cccc1C +Cc1n[nH]c(C)c1CCOC(=O)c1cccc(NC(=O)C2CC2)c1 +CC(C)OCCC(=O)N(Cc1ccc(C#N)cc1)C(C)C +COC(=O)CCCCc1cc2c(s1)CCCC2=O +COc1cc(CO)ccc1OCC(=O)Nc1ccccc1C +O=C(c1cccnc1N1CCOCC1)N1CCc2ccccc21 +COc1cccc(OC)c1C(=O)NCC(C)(O)c1ccc(F)cc1 +COc1ccc(C(=O)NCCOc2c(C)cccc2C)nn1 +C#CCOCC1CCCN(C(=O)c2ccc(OC(C)C)cc2)C1 +CCC(=O)N1CCN(Cc2cnc(-c3ccc(C)cc3)s2)CC1 +CCc1ccc(C(=O)NCc2cn(-c3ccccc3)nn2)cc1 +Cc1ccc(-c2nnn(CC(=O)Nc3cccnc3)n2)cc1 +Cc1noc(C)c1CSc1nnc2c(Cl)cc(Cl)cn12 +COCc1ccccc1C(=O)Nc1cnn(-c2ccccc2F)c1 +CC(=O)c1ccc(OS(=O)(=O)c2cc(F)c(F)cc2F)cc1 +CCSc1cc(C(=O)N(C)Cc2cc(C)on2)ccn1 +Cc1ncsc1CCOc1ccc(Br)cc1N +COC(=O)c1ncn(Cc2ccc(OC)c(Br)c2)n1 +Cc1ccc(C2NCCc3c(OC(C)C)cccc32)cn1 +CC(C)S(=O)(=O)NC1CCN(Cc2ccccc2)C1=O +CC(C)c1nnc(NC(C(=O)N2CCOCC2)C(C)C)s1 +COCCOc1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +O=C(NCC1(c2ccccc2)CCOCC1)C1CC=CCC1 +Cc1cccc(NC(=O)Cn2ccc3sccc3c2=O)c1 +C#Cc1cccc(NC(=O)Nc2ccccc2OC)c1 +c1ccc(-c2ccccc2OCc2nnc3n2CCC3)cc1 +COc1ccc(CC(C#N)C(=O)NC2CCCCC2)cc1O +Cc1noc(C2CC3CN(C(=O)c4ccoc4)CC3O2)n1 +Cc1cc2ncn(CC(O)CSc3nccn3C3CC3)c2cc1C +CCOCCCNC(=O)c1c(-c2cccc(Cl)c2)noc1C +CC(C)N1CC(C(=O)Nc2ccc(Cl)cn2)CC1=O +CC(C)S(=O)(=O)NCC1CCCN(C(=O)C#Cc2ccccc2)C1 +CC(C)=Cc1nnc(C(N)c2cc(F)ccc2F)o1 +Cc1nc(NC(=O)Cn2nc(-c3cccs3)ccc2=O)sc1C +CC(=O)NC(C(=O)Nc1ccc(SC(F)F)cc1)C1CCCC1 +COCc1cc(CN2CC(C)(c3ccccc3)CCC2=O)n[nH]1 +c1cc(-c2ncc(-c3ccncc3)c(-c3ccncc3)n2)ccn1 +COc1ccccc1NCC(=O)N1CCCC1c1cccs1 +Cc1nc(-c2ccc3c(c2)OCO3)sc1CCO +c1ccc(-c2noc(N3CCCC(OCc4ccccn4)C3)n2)cc1 +CC(C)c1ncc(CN2CCN(Cc3ccon3)CC2)s1 +CC(N)C(=O)c1ccc2c(c1)N(C)CC(C(C)C)O2 +CCOC(=O)c1c(NC(=O)c2ccnn2C)sc2c1CCCCC2 +O=C(NCc1ccccn1)N1CCCC1c1ccc2c(c1)OCO2 +COC(=O)C(C)Sc1nc2cc(Cl)ccc2n1C +Cc1ccc(NC(=O)C(Oc2ccccc2C#N)C(C)C)nc1 +CCC(C(=O)NCCc1nc(C)cc(C(F)(F)F)n1)n1cccn1 +NC(=O)c1nccn1-c1ccc(C(F)(F)F)cc1 +Cc1noc(CNc2cc(NC(=O)c3ccccc3)ccc2C)n1 +CCN(CC)C(=O)COc1cccc(NC(=O)C2CC=CCC2)c1 +CC(C)C(NC(=O)c1ccnc2cccnc12)C(=O)N1CCOCC1 +Cc1cccc(NS(=O)(=O)c2ccc(-n3cccn3)cc2)c1 +CCOc1cccc(Oc2ccc(C(C)=O)cc2N)c1 +CC(C)n1ccc(C(=O)Nc2nc3c(F)cccc3s2)n1 +Cn1nc(-c2ccc(F)cc2F)cc(CC#N)c1=O +CN(C)C(=O)CSc1nnc(COc2ccc(Cl)cc2)n1C +CCn1cc(C(=O)OCC(=O)N2CCCc3ccccc32)cn1 +Cc1cccc(-n2ncc3c2ncn2c(-c4ccccc4O)nnc32)c1 +O=C(NCc1ccncc1)C1CCCN(c2nnc3ccccn23)C1 +CNC(=O)CNc1cccc(C(=O)NCCOC)c1 +CCC(=O)Nc1cccc(C(=O)Nc2ccc3c(c2)COC3)c1 +O=C1Cc2cc(C(=O)CCC3CCCC3)ccc2N1 +Cc1cc(S(=O)(=O)NC2CC2C)ccc1Br +CC(CNC(=O)N1CCN(c2ncccn2)CC1)Cn1cccn1 +CN(CCOc1ccccc1)Cc1nc2c(F)cccc2[nH]1 +COc1ccc(O)c(C(=O)OCc2nnc(-c3ccccc3)o2)c1 +COC(=O)c1sccc1NC(=O)Nc1cccc(C)c1 +CCOC(=O)CN(C)C(=O)Nc1ccnn1C(C)C +O=C(OCC1CCCO1)c1ccccc1SCc1cscn1 +CC(=O)N1CCC(C(=O)Oc2cc(Cl)ccc2Cl)CC1 +O=c1[nH]c(CSc2nncn2C2CC2)nc2ccc(Cl)cc12 +CC(C)NC(=O)C1CCCN(c2ccc3nnnn3n2)C1 +CCOc1cc(CNc2ncnc3c2cnn3C)ccc1OC(F)F +CN(C(=O)CSc1nnc(NC2CC2)s1)C1CC1 +CN(CCNCc1cc(=O)c2cccc(Cl)c2[nH]1)S(C)(=O)=O +O=c1[nH]cnc2c1CCN(S(=O)(=O)c1cccs1)C2 +COc1ccccc1NC(=O)Cc1ccc2c(c1)OCCO2 +CCOc1cc(N)cnc1Nc1cc(OC)cc(OC)c1 +O=C(COc1ccccc1F)NCc1nc(Cc2ccccc2)no1 +O=C(Cc1cccs1)OCc1cc(=O)oc2cc(O)ccc12 +CCOC(=O)N1CCC(NC(=O)c2ccc(N)cc2)CC1 +Cc1ccc(C(O)CNC(=O)c2ccccc2C)cc1 +C#CCSc1nnc(-c2ccc(OC)c(OC)c2)o1 +COc1cc(NC(=O)c2cc(N)c[nH]2)cc(OC)c1 +CCc1ccccc1Nc1nc(C)c(C(=O)NCCOC)s1 +COc1c(NC(=O)Cc2ccc(F)c(F)c2)c(C)nn1C +N#Cc1ccc(-c2noc(C3CCC(F)(F)CC3)n2)nc1 +CC(=O)Nc1cc(S(=O)(=O)Oc2c(C)nn(C)c2C)ccc1C +Cc1ccc(CNC(=O)Nc2cccn(Cc3ccccc3)c2=O)cc1 +CC(C)CCN1C(=O)CNc2cc(Br)ccc21 +COc1ccc(OCC(=O)NC(C)c2ccc(OC)cc2)cc1 +Cn1cnnc1SCc1cc(Cl)ccc1OC(F)F +N#Cc1cc(N2CCN(c3ncccn3)CC2)ccn1 +CC1CCC(NC(=O)CNC(=O)c2ccccc2Cl)CC1 +CCc1nnc(NC(=O)c2ccnc(Oc3ccccc3)c2)s1 +COc1ccc2c(c1)[nH]c(=O)n2Cc1cccnc1 +COCCNC(=O)c1ccc(-n2ncc(C(=O)OC)c2N)cc1 +Cc1cc(NC(=O)c2c(C)[nH]c3ccccc23)n(C)n1 +CCCOc1ncccc1CNC(=O)Nc1ccc(C(=O)NC)cc1 +CCNC(=O)CSc1nnc(-c2c[nH]c3ccccc23)n1C1CC1 +CC1(C)CN(CCC(=O)Nc2cccc(Cl)c2)CCO1 +CCOc1cc(NC(=O)Cc2ccccc2)c(OCC)cc1N +Cc1ocnc1CNC(=O)Nc1cc(C#N)ccc1OC(C)C +CCc1cccc(NS(=O)(=O)c2ccccc2C#N)c1 +Cc1ccc(S(=O)(=O)NCC2CCCCO2)c(C)c1 +Cc1ncc2c(n1)CCN(Cc1ccc(-n3cccn3)cc1)C2 +Cc1cccc(C2NCCc3c(F)cc(Cl)cc32)n1 +CCOc1ccc(N(CCC#N)C(=O)CNC(=O)NC)cc1 +Cc1nnc(N2CCc3cncnc3C2)c(C#N)c1C +CC(=O)Nc1nc(CC(=O)NCCc2ccc(F)cc2)cs1 +O=C(Nc1ccc2c(c1)CCC2)c1ccc(Cn2cncn2)cc1 +CCC(C)C(NC(=O)c1cnn(-c2ccccn2)c1C)C(N)=O +CCOC(C)c1nc(CN2CCN(CC(=O)NC)CC2)cs1 +Cc1ccccc1-c1noc(-c2nnn(-c3cccc(F)c3)c2N)n1 +O=C(Cc1ccc2c(c1)CCC2)N1CCCCC1CN1CCOCC1 +O=C1CCCN1c1ccccc1NS(=O)(=O)c1ccc(F)cc1 +O=C(OCc1ccn(-c2c(F)cccc2F)n1)c1cscn1 +CCCOc1cccc(NC(=O)c2ccc(C)o2)c1 +Cc1cnc(C(=O)NCC2(c3ccc(F)cc3F)CC2)cn1 +Cc1nc(CCCNC(=O)Nc2ccc3c(c2)C(=O)OC3)sc1C +Cc1ccc(N2CCC3OC(C(=O)N4CCN(C)CC4)CCC32)nn1 +CCn1nc(C)cc1NC(=O)c1cc(OC)cc(OC)c1 +O=C1NCCCc2[nH]c(CCOc3ccccc3)nc21 +O=C(c1ccco1)N1CCc2ncnc(-c3cncnc3)c2CC1 +COc1cccc(NC(=O)CC(C#N)c2ccccc2C)c1 +C#CCN1CCC(C(=O)Nc2ccc[nH]c2=O)CC1 +Cn1ccnc1N1CCN(C(=O)CC2CCCCC2)CC1 +CC(Sc1ccccn1)C(=O)Nc1nnc(C(C)(C)C)s1 +CCN(CC)C(=O)N1CCC(C(=O)N(C(C)C)C2CCC2)CC1 +CCCCN(CC)S(=O)(=O)c1cccc(C(N)=O)c1 +O=C(Nc1ccc(-n2nccn2)cc1)N1CCC(O)C1 +O=C(c1ccc(F)cc1)N1CCN(CC2=C3C=CC=CC3N=C2)CC1 +Nc1n[nH]c(CCc2ccccc2Cl)c1-c1ccccn1 +CNc1ccnc(-c2c(F)cccc2OC(C)C)n1 +CC(=O)NC(C(=O)Nc1nnc(CC(C)C)s1)C(C)C +Cc1cc(C)cc(NCc2cc(=O)n3c(C)csc3n2)c1 +COc1ccc(Cl)cc1C(=O)OCC(=O)NC(C)C +CCC(=O)Nc1ccc(-c2ccc(N3CCOCC3)nn2)cc1 +COc1cc(CNCCc2ccncc2)ccc1O +O=C(CC1CCN(C(=O)Nc2cccnc2)CC1)N1CCCC1 +COc1ccc(CC(C#N)C(=O)Nc2ccccc2F)cc1O +COc1cc(C(=O)N(C)Cc2ccc(F)c(F)c2)cc(OC)c1C +NC(=O)c1ccccc1NC(=O)Nc1ccc(Cl)cc1F +COc1ccc(CC(=O)N2CC(OC)C3COCC32)cc1 +Cc1nc(COc2ccccc2C(=O)NC(C)Cn2ccnc2)no1 +O=C(NCC(=O)N1CCC2(CC1)OCCO2)c1ccoc1 +Cc1ccc(C)c(S(=O)(=O)C(C)C(=O)N2CCC(C)CC2)c1 +C=CCn1nc(C#N)cc1-c1ccc(OC(C)C)cc1 +CC1CC2CN(C(=O)c3ccc4ccccc4c3)CCC2O1 +CC1Oc2ccccc2OC1C(=O)NCc1ccc2c(c1)OCO2 +CCn1nnc2cc(C(=O)N(C)c3ccc(Cl)cn3)ccc21 +CC(C)NC(=O)C1CCN(C(=O)Nc2ccccc2)CC1 +Cc1cc(C(=O)Nc2cccc(Cn3cccn3)c2)nc(N(C)C)n1 +COc1c(Cl)cccc1NC(=O)N(C)CC(=O)Nc1ccccc1 +CN(Cc1ccncc1)C(=O)c1ccc(Br)cc1O +Cc1nc(CNc2nccn(CC(C)C)c2=O)cs1 +Cc1cccc(-c2[nH]ncc2C(=O)NCc2ccccc2)c1 +O=C(c1ccc[nH]1)N1CCCn2c(nnc2Cn2cccn2)C1 +CC(CNC(=O)Nc1ccn(Cc2ccccc2)n1)Cn1cccn1 +Cn1c(=O)c2cc(NC(=O)c3cc(F)cc(F)c3)cnc2n(C)c1=O +Cc1nn(C)c(C)c1CC(=O)N1CCCC1c1cnn(C)c1 +CN(Cc1ccc(O)cc1)C(=O)CNC(=O)C(C)(C)C +Cc1ccc(S(=O)(=O)Oc2cc3nc(C)cc(C)n3n2)cc1 +Cn1ccc(=O)n(CC(=O)c2ccccc2F)c1=O +CC(C)(CNC(=O)c1ccccc1Nc1ccccc1)C(N)=O +O=C(Cn1nnc2ccccc21)NC1(c2ccc(Cl)cc2)CCC1 +Nc1ccc2nc(NC(=O)c3cccc(F)c3)sc2c1 +O=C(Oc1ccc(F)cc1Br)C1CC1 +CN1CCN(CCO)C(=O)C12CCN(Cc1nccs1)CC2 +Cc1ccn2cc(C(=O)NC3CCN(S(C)(=O)=O)CC3)nc2c1 +O=C(CC1CCN(C(=O)Nc2ccccc2F)CC1)N1CCCCC1 +O=C(COc1cccc(Cl)c1)Nc1ccc(O)cc1 +O=C(CCc1cccs1)Nc1cccc(C(=O)C2CC2)c1 +Cc1ccc(C(C)NC(=O)NCC(C)(C)C(N)=O)cc1F +COCCn1cnc2c(oc3nc4c(cc32)COC(C)(C)C4)c1=O +Cc1cc(NC(=O)COC(=O)c2cc3c(s2)CCCCC3)n(C)n1 +CCCN(CC(=O)N(C)C)C(=O)c1ccc(-c2nc(C)cs2)cc1 +CC(C)c1nc(C2CCCN2C(=O)C2CSc3ccccc32)no1 +CCCNC(=O)C1CCCN(C(=O)c2c(C)oc(C)c2C)C1 +Cc1occc1C(=O)NCC(=O)Nc1ccc(C(N)=O)c(Cl)c1 +Cc1ncc(Cn2c(C)nn(C(C)(C)C)c2=O)s1 +CC(Cn1cncn1)NC(=O)CCSc1ccccn1 +COC(=O)c1cccc(-n2nc(C(C)C)c3c2CCNC3)c1 +CN(C(=O)COCC1CC1)c1cccc2ncccc12 +CCc1nnnn1Cc1nc(C)c(-c2ccc(Cl)cc2)o1 +CCN(CCC(=O)OC)C(=O)Cc1cn2ccsc2n1 +CC1(NC(=O)CCNC(=O)c2ccco2)Cc2ccccc2C1 +Cc1ccc(NC(=O)c2nnc(COCC(=O)NC(C)C)s2)cc1 +CCCN(CCO)S(=O)(=O)N1CCCCC1 +O=C(Cn1nnc2ccccc2c1=O)N1CCC(Nc2ccccc2)C1 +CC(=O)NCCNC(=O)c1ccccc1S(C)(=O)=O +Nc1nonc1-c1nc2cc(Cl)ccc2n1C1CC1 +CCC(C)NC(=O)Cc1coc2c(C)c(C)ccc12 +Cc1nnc(CNC(=O)Cc2cccc(C(F)(F)F)c2)n1C +CCS(=O)(=O)N1CCCC(n2nnn(-c3ccccc3)c2=O)C1 +COc1ccc(CNC(=O)c2ccc(C(N)=O)cc2)cc1F +CCOC(=O)c1cccc(N2C(C)=NS(=O)(=O)c3cccnc32)c1 +Cc1cccc(C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)c1C +COc1cccc(C(=O)Nc2ccc(C(N)=O)cc2)c1F +CCc1nc(CCNC(=O)C2C3CCCC32)sc1C +COCCn1c(C)cc(=O)c(O)c1CN1CC(C)OC(C)C1 +Cc1cc(C(=O)N2CCN(CC(O)C(C)(C)C)CC2)c2[nH]ncc2c1 +CC(NC(=O)NC(CC(F)(F)F)c1ccc(F)cc1)C1CC1 +CCCCC(=O)Nc1cnn(-c2ccccc2F)c1 +CN(C)S(=O)(=O)Cc1ccc(OC(F)(F)F)cc1 +CC(=O)c1ccc(S(=O)(=O)N2CCC(O)CC2)cc1 +CC(=O)Oc1ccc(C(=O)NCCc2c[nH]c3ccc(C)cc23)cc1 +O=S(=O)(Cc1ccon1)c1nnc(NCC(F)(F)F)s1 +O=C(Cn1c(C2CC2)nc2ccccc21)N1CCOCC1C1CC1 +CCn1cnnc1CNC(=O)C1CCN(c2cc(C)cc(C)c2)C1=O +Cc1sc(C(=O)NCc2n[nH]c(=O)[nH]2)cc1-c1ccc(F)cc1 +C=CCN(Cc1cccc2c1OCCCO2)CC(F)(F)F +CC1CN(CCNC(=O)c2cc(C(C)C)[nH]n2)CC(C)O1 +Cc1n[nH]c(C)c1NC(=O)c1cccc(Oc2ccncc2)c1 +CCOC(=O)CCNC(=O)c1cc2cc(C)ccc2o1 +Cc1cc(C(=O)NCC(=O)Nc2ccc(Cl)cc2)[nH]n1 +OC1CCN(c2nc(C3CC3)nc3scc(-c4ccccc4)c23)C1 +Cc1nc2ccc(NC(C(N)=O)c3ccccc3)cc2s1 +CCCCCNC(=O)N(C)Cc1ccc(C(=O)NC)cc1 +Cc1noc(C)c1N(C)C(=O)Cc1nc(-c2ccccc2)oc1C +Cc1cc(C(=O)N2CCN(C(=O)c3ccc(Cl)cc3)CC2)no1 +CNS(=O)(=O)C1CCOCC1Cc1cccc(F)c1 +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1cccc2ccccc12 +COc1cc(F)c2c(c1)C(c1ccc(=O)[nH]n1)NCC2 +O=C(NCCCn1ccnc1-c1ccccc1)c1ccco1 +COC(=O)C1CCCC1NC(=O)Nc1ccc2oc(C3CC3)nc2c1 +N#Cc1cccnc1N1CCCC(CO)(CCOc2ccccc2)C1 +COc1cccc(CCC(=O)c2cccnc2)c1O +Cc1ccsc1CN1CCCC1c1ccccn1 +CC(C)CCOc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1 +NC(=O)Cn1nc(-c2cccc(F)c2)c2c1CCCC2=O +O=C(c1ccccn1)N1CCN(Cc2nc3ccccc3s2)CC1 +Cc1nc2c(s1)C(N(C)Cc1cccnc1C)CCC2 +Cc1ccc(NC(=O)C(Sc2n[nH]c(N)n2)c2ccccc2)cc1 +O=C(CCn1nnc2ccccc2c1=O)NCc1cc2ccccc2o1 +Cc1ncoc1C(=O)N1CCN(c2ccccc2F)CC1 +Cc1csc(CCNC(=O)c2cccnc2SC(C)C)n1 +CS(=O)(=O)Nc1ccc(C(=O)NCc2ccco2)cc1 +Cc1cc(S(=O)(=O)NCC(C)O)c(Cl)cc1Br +COc1cccc(-c2ccc(N)c(=O)n2CCC(C)C)c1 +O=C(c1ccc(-n2cccn2)nc1)N1CCC(c2ccc(O)cc2)CC1 +COc1ccc(C(=O)Nc2ccccc2C#N)cc1N +CC(=O)Nc1ccc(SCCCc2c(N)nc(N)nc2N)cc1 +c1ccc(C(c2ccccc2)c2nncn2C2CC2)cc1 +CS(=O)(=O)N1CCCC1C(=O)Nc1nc2c(s1)CCCC2 +CCCCN(C)C(=O)Cc1c(C)nc2ccc(N)cn12 +COc1ccc(C(C#N)NC(C)C)cc1Br +COc1ccc2c(c1)C(c1ccc(OC)c(O)c1)NCC2 +CCCc1cc(=O)n(CC(=O)NCCc2ccccc2)cn1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1cnoc1C +CCCn1nnnc1CN1CCCc2cc(C)cc(F)c21 +COc1ccc(C(=O)c2ccccc2)c(OC)c1O +COC1(C)CC(N(C)C(=O)CNC(=O)c2ccccc2C)C1(C)C +CC1(C)CN(CC(=O)Nc2ccccc2)c2cc(N)ccc2O1 +Nc1ccc2oc(=O)n(Cc3cccc(Br)c3)c2c1 +FC(F)CN1CCN(Cc2ccccc2OCc2ccccn2)CC1 +CN(C)C(=O)COc1cccc(NC(=O)CCc2ccccc2F)c1 +CN(C)C(=O)N1CCC(C(=O)OCc2ccccc2F)CC1 +Cn1c(SCC(=O)Nc2ccc(F)cc2)nnc1C1CCCCC1 +CCC1COCCN1Cc1c(C)nn(CC)c1C +CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc1sccc1C(N)=O +Cn1c(=O)n(CC(=O)N2CCOCC2C2CC2)c2ccccc21 +CC(=O)Nc1c(-c2cc(C)cc(C)c2)nc2ccccn12 +Cn1c(NC2CCc3ncnn3C2)c(C#N)c(=O)n(C)c1=O +COC(=O)c1c[nH]c(-c2cc(Br)cs2)n1 +Cc1cccc2sc(NC(=O)c3cccnc3N3CCCC3)nc12 +OCCCn1c(-c2cccc(F)c2)nc2cc3c(cc21)OCCO3 +Cc1nn(-c2ccccc2)c(C)c1NC(=O)NC1CCCC(C)C1 +Cc1ccc(N2C(=O)C(NC(=O)C3CC3)(C(F)(F)F)N=C2O)cc1 +O=C(COC(=O)C1CCC1)Nc1ccccc1C(=O)NC1CCCC1 +O=C(c1csc(-n2cccc2)n1)N1CCC2(CC1)OCCO2 +NC(=O)c1csc(CNc2ccc(Oc3ccccc3)cn2)c1 +Fc1ccc(-c2n[nH]cc2CNc2cnn(-c3ccccc3)c2)cc1 +CN(CCc1nccs1)C(=O)C1CCCN(CC(F)(F)F)C1 +Cc1ccc(CNC(=O)CSc2nnc(-c3ccncc3)o2)cc1 +CCOC(=O)C1CCCCN1C(=O)c1cn(C2CCCCC2)nn1 +O=C(Cc1cccs1)NCc1ccc(OCC(F)(F)F)cc1 +CC(NC(=O)c1cccc(F)c1)c1ccccc1NS(C)(=O)=O +CC(CCc1ccccc1)NC(=O)C1CCCN1C(N)=O +Cc1ccc(C(=O)N(C)CCOCC2CC2)cc1F +Cc1cc(N)cc2c(=O)cc(C(=O)Nc3ccccn3)oc12 +Cc1csc(C(=O)N2CC(c3nc(-c4cccs4)no3)C2)c1 +Cc1cc2nc(-c3ccccc3)cc(NC(C)c3cnn(C)c3C)n2n1 +COCCS(=O)(=O)N1CC(c2ccc(F)cc2)CC1C +COC(=O)c1c(C)[nH]c(C(=O)N2CCC(c3ccccc3)CC2)c1C +CC(C)CCN(CCC(C)C)C(=O)Nc1cn[nH]c1 +CCCOCC(=O)N1CC(C)Sc2ccccc21 +Cc1cccc(C(C)C)c1NC(=O)Cn1nnc(C(N)=O)c1C +CC(C)C(C#N)N1CCN(C(=O)CN2CCOCC2)CC1 +Cc1ccc(NC(=O)C2CCN(S(C)(=O)=O)CC2)c(F)c1 +Cc1ccc(S(=O)(=O)N2CCCC(C(N)=O)C2)c(C)c1 +CCc1ccc(OC)c(-c2cn3c(N)csc3n2)c1 +COc1ccc(C(NC(=O)c2ccccn2)C(C)C)cc1 +Cc1[nH]ncc1C(=O)N1CCc2c(F)ccc(F)c2C1 +CCOC(=O)C(Sc1nnc2n1CCCCC2)c1ccccc1 +CC(C)C(=O)c1ccc(F)c(S(=O)(=O)N2CCCCC2)c1 +Cc1nn(CC(O)COc2ccc(Cl)cc2)c(=O)c2ccccc12 +CCNC(=O)c1cccc(N(C)S(C)(=O)=O)c1C +CCS(=O)(=O)N(C)Cc1cccc2ccccc12 +CCCC(C)(NC(=O)c1ccc(-c2ccccc2)[nH]c1=O)C(=O)OC +O=C(NCCCOc1cccc(Cl)c1)c1cnn2c1SCC2 +COc1cc(OC)nc(NC(=O)CSc2nc3ncccn3n2)n1 +CCNC(=O)CCS(=O)(=O)c1ccc(C)cc1 +CC(=O)NC(CC(=O)NC1CCCCC1C)c1ccc(Cl)cc1 +CC(C)(C)CN(CCC#N)C(=O)c1cnc(-c2ccccc2)nc1 +Cn1c(N)nnc1SCc1nc(-c2ccsc2)no1 +CCOC(=O)CSc1nccc(-c2cn(CC)nc2C)n1 +Cc1c(NCc2ncc(-c3ccc(F)cc3)o2)cccc1C(N)=O +Cn1cnc(CNC(=O)NCCOc2ncc(Cl)cc2Cl)n1 +Cc1cccc(C(=O)N2CCCC2)c1NC(=O)NCC1CC=CCC1 +CCOCCOc1c(Cl)cccc1NC(=O)NC +CNC(=O)c1ccc(CN(C)CC(=O)c2cc(C)[nH]c2C)cc1 +N#Cc1ccccc1CN1CCCC(C(F)(F)F)C1 +CCCNC(=O)c1ccc(NC(=O)CCC2CCCO2)cc1Cl +C#CCN(CC=C)c1nc2nonc2nc1N1CCOCC1 +O=C(c1ccc(O)cc1)N1CCN(c2cccc(Cl)c2)CC1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1cccc(C(=O)OC)c1 +CCN(CC(=O)NC)C(=O)c1sc(Cc2ccccc2)nc1C +Cc1ccc(NCc2ccc(Cl)c(F)c2)cn1 +COc1ccccc1CC1CCCN1Cc1cnnn1C +Cc1n[nH]c(C)c1C(C)C(=O)Nc1cccc(Cl)c1C +CCCn1nnnc1Cn1cnc2cc(F)c(F)cc21 +O=C(CCNC(=O)c1cc2cccn2cn1)Nc1ccc(F)cc1 +CNC(=O)c1ccc(NC(=O)c2cc(N(C)C)ccn2)cc1Cl +O=C(NC1CCCCC1)C1CCCN(C(=O)C2CC2c2ccco2)C1 +c1ccc(CC2CCCCN2Cc2nnc(C3CC3)o2)cc1 +Cc1cc2cc(NC(=O)c3csc(-c4ccco4)n3)ccc2[nH]1 +COC(=O)CC(NC(C)C)C(=O)c1cc(F)ccc1F +CCOC(=O)CCCNC(=O)c1cncc(Br)c1 +COc1ccc(NC(=O)N2CCCC2C(=O)N2CCN(C)CC2)cc1 +COc1ccc(-c2c(-c3ccco3)noc2N)cc1 +COc1ccc(-c2noc(NCCc3ccccc3)n2)cc1OC +O=C(C1CN(Cc2ccccc2)CCO1)N1CCC(c2ccco2)C1 +CCC1CN(C(=O)c2cc(OC)ccc2N)CCO1 +NC(=O)C1(NC(=O)c2cccc(OCC(F)F)n2)CCCCC1 +Cc1ccc(C(=O)NCCOc2cccc(N)c2)o1 +COc1cc(C(=O)COc2cccc(N)c2)c(OC)cc1C +Cc1nn(C)c(N)c1S(=O)(=O)NCc1ccco1 +CC1CC1C(=O)Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 +COc1cc(OC)cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +Fc1ccccc1CCc1nc(-c2cccnc2)no1 +CCC(CO)Nc1nc(C)nc2c1oc1ccccc12 +O=C(Cc1c[nH]c2ccccc12)NCCc1ccn(-c2ccccc2)n1 +O=S(=O)(NCC1CCOC1)c1ccc2ccccc2c1 +CCCCCCN1C(=O)CSc2ccc(N)cc21 +CCN(CCC#N)C(=O)COc1ccc(Cl)cc1C(C)=O +Cc1csc(CNC(=O)NCc2cccc(Cn3ccnc3)c2)n1 +Cc1ccc(C(C)NC(=O)c2c(C)oc(C)c2C)cc1F +O=C(CCCOc1ccccc1)Nc1ccc2c(c1)OCCO2 +Cn1nnnc1-c1cccc(NC(=O)Cc2ccc(F)c(F)c2)c1 +CC(C)(C(=O)N1CCN(C(=O)CO)CC1)c1ccc(F)cc1 +COc1ccc(F)c(NC(=O)NC(C)CC(C)(C)OC)c1 +O=C(Nc1cc(N2CCCC2)ncn1)c1c[nH]c(=O)[nH]c1=O +O=C(NC1CCC(O)CC1)N1CC(OCCCOc2ccccc2)C1 +CCCNC(=O)CNC(=O)Nc1ccccc1-n1cccn1 +CCC(=O)N1CCCC(c2nc(-c3ccncc3)no2)C1 +CCOc1ncccc1CNC(=O)c1cnc(Nc2ccccc2)nc1 +Cc1occc1-c1nnc(-c2ccc(CN3CCCC3=O)cc2)o1 +Cc1cnnn1-c1ccc(C(=O)Nc2cccc3ccccc23)cc1 +COc1ccc2c(=O)c(C(=O)NCc3cccnc3)c[nH]c2c1 +CC1Cc2cc(-c3cc(CNC(=O)c4cccs4)no3)ccc2O1 +C#Cc1cccc(NCc2cc(C(N)=O)ccc2F)c1 +Cc1ccc(N2CC(C(=O)N(C)CC(F)F)CCC2=O)cc1C +CN(C)c1ccc(C(=O)NC2CCCc3ccccc32)cc1 +COc1ccc(CN2CCN(C(=O)NCc3ccccc3)CC2)cn1 +Cc1cc(F)c(C(=O)N2CCN(C3CCOCC3)CC2)cc1F +O=C(NCCNS(=O)(=O)c1ccccc1)C1(c2ccccc2)CC1 +CCc1noc(-c2cccc(OCC(=O)N3CCOCC3)c2)n1 +Cc1oc(-c2ccccc2)nc1CC(=O)NC(C)CO +NC(=O)C(NC(=O)c1[nH]c2ccc(F)cc2c1Cl)c1ccccc1 +CC1CCCC(C)N1C(=O)COC(=O)c1ccc(CO)cc1 +Cc1cc(-c2cnc(N3CCOCC3)nc2-c2sccc2C)on1 +CCN(Cc1cccc(NC(=O)NCCCO)c1)C(C)=O +CCC(=O)Nc1cccc(C(=O)Nc2cccc(-n3cnnc3)c2)c1 +NC(=O)c1ccc(NC(=O)Cn2cnc(N)n2)cc1 +O=C(CCCOc1ccccc1)Nc1nc2ccccc2[nH]1 +O=C(NC1CCN(C(=O)c2c[nH]c3ccccc23)CC1)C1CC1 +Fc1cc(NCc2ccc[nH]2)cc(C(F)(F)F)c1 +O=C(OCc1cc(-c2ccco2)on1)c1ccncc1 +CCC(=O)N1CCCc2c(NC(=O)c3ccc(F)cc3)cccc21 +CCOc1ccc(C(=O)N2CCN(c3cccc(C)c3)CC2)cc1 +OC(c1ccc2c(c1)COC2)c1c(F)cccc1F +CCc1ccc(C(=O)N2CCn3c(nnc3C(C)C)C2)o1 +O=C(CCC(=O)c1cccs1)Nc1ccc2[nH]c(=O)[nH]c2c1 +COc1ccc(OC)c(CC(CO)c2cccs2)c1 +Cn1nc(C(=O)NC2CCCC2)c2c1CCN(Cc1ccncc1)C2 +CCOc1cc(-c2nc(-c3cnccn3)no2)cc(Cl)c1O +O=C(CCn1c(=O)[nH]c2ccccc2c1=O)Nc1cccnc1 +CC(=O)NC(C)(C)c1noc(-c2ccc(OCC(F)(F)F)nc2)n1 +Cc1nc(Cn2cnc3cc(F)c(F)cc32)cs1 +CSc1nnc(CCCNC(=O)Nc2cn[nH]c2)n1C1CCCC1 +Cn1ccc(C(=O)NCC(C)(C)c2cccs2)cc1=O +O=C(NCCCCc1nccs1)c1cccc(-n2cccn2)n1 +CC(C)C(NC(=O)NCc1ccccc1)c1ccc2c(c1)OCCO2 +Cc1nc2nccc(-c3ccc(OCc4ccccc4)cc3)n2n1 +Cc1nnsc1-c1nnc2sc(Cc3c(C)noc3C)nn12 +Cn1cc(NC(=O)NC2(c3cccc(Br)c3)CCC2)cn1 +CCCc1nc(NCc2ccncc2)c(C#N)c2c1CCCC2 +CC1CCN(C(=O)Nc2ccc(C(=O)N3CCOCC3)cc2)CC1 +COc1ccc(C)cc1C(=O)CNc1cccc(NC(C)=O)c1 +COCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +Cn1cnnc1-c1cccc(NC(=O)c2cccs2)c1 +COCC(NC(=O)c1c(Cl)c2ccccc2n1C)C(N)=O +C=C(C)CN(CC)C(=O)c1cc(Br)c[nH]1 +CC(NC(=O)CSc1nnc2n1CCCCC2)c1ccccc1 +CC1(C)C(=O)NCCN1C(=O)c1ccc(-n2cnc3ccccc32)nc1 +COCCN(CC(=O)N(C)C)Cc1cnc2ccc(C#N)cn12 +COCC(C)(C)CNC(=O)C(N)c1ccccc1 +CN1CCN(C2CCN(C(=O)c3ccc(Cl)cc3)CC2)C1=O +COc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1 +O=C(CCCn1cncn1)Nc1nc(-c2ccco2)n[nH]1 +Cc1ccsc1CNC(=O)c1c[nH]c(=O)c(Cl)c1 +N#CC1(NC(=O)CSc2nnnn2-c2ccccc2)CCCCC1 +O=C(Nc1cc(F)ccc1NC(=O)c1ccccn1)c1cccnc1 +CC(C)(C)C(=O)Nc1nc(CC(=O)N2CCc3ccccc32)cs1 +Cn1nccc1COC(=O)c1cc(-c2ccccn2)ccc1Cl +O=C1COC(=O)C1C(=O)Nc1cccc(C(F)(F)F)c1 +CCN(C)c1ccc(C(=O)Nc2cc(-n3cnnn3)ccc2C)cc1 +CC(C)C(C(=O)Nc1ccc(O)cc1F)N1CCCC1=O +Cc1ccc(CC(C)NC(=O)N2CCN(C(=O)N(C)C)CC2)c(C)c1 +CCc1ccc(CNc2nnnn2-c2ccccc2)s1 +CCC(NCc1nnc(C)s1)c1ccccc1Br +COCCNC(=O)C1(C)CCC(=O)N1c1ccc(OC)cc1OC +O=C1CCC(NS(=O)(=O)c2cc(F)cc(F)c2)CN1 +Cc1noc(C(C)N2CCN(C(=O)c3cc4ccccc4[nH]3)CC2)n1 +COc1ccc(N2CC(NC(=O)CC(C)C)CC2=O)cc1 +COC(=O)C1=C(C)Nc2nnnn2C1c1c(Cl)cccc1Cl +COC(=O)C(C)CN(C)C(=O)C1CC(=O)N(C)C1 +CCC(NC(=O)Cn1ccccc1=O)c1ccc(Cl)cc1 +CC(=O)N1CCN(C(=O)CC(C#N)c2ccc(C)cc2)CC1 +COc1ccc(F)cc1C(=O)CNS(C)(=O)=O +Cc1cc(C)c(C(=O)C2CCCN2S(C)(=O)=O)c(C)c1 +CC(C)N(C(=O)Cc1cn2c(nc1=O)SCC2)C1CCCCC1 +C=CCN1C(=O)C(C)Oc2c(OC)cc(CO)cc21 +CCOc1ccc(-c2nc(CSc3nncn3C)cs2)cc1 +Cc1ccc(C)c(Cn2cccc2CNC(=O)NCc2ccco2)c1 +CCOc1cccc(C(C)NC(=O)Cc2c(C)noc2C)c1 +Cc1nc(CN2CCN(C(C)C(=O)NC(C)(C)C)CC2)cs1 +O=C(NC1CCCC1)NC(CCCO)c1ccccc1 +CN(C)C(=O)C1CCN(C(=O)CC2CC3CCC2C3)CC1 +Cc1nc(-c2ccc(C(F)(F)F)cc2)[nH]c(=O)c1C +O=C(CNC(=O)Nc1nncs1)Nc1ccccc1 +Cc1ccc(NC(=O)NCc2cnn(C)c2C)cc1-c1ncco1 +COc1ccc(CN(C)C(=O)c2ccnc(OC3CCC3)c2)cc1F +COCCn1ccc(NC(=O)c2c[nH]nc2-c2ccc(Cl)cc2)n1 +CC(C)(C)c1csc(C2CCCCN2C(=O)CCn2ccnc2)n1 +O=C(COc1ccc(O)cc1)Nc1cccc(Cl)c1 +CC(CCc1ccccc1)NS(=O)(=O)c1ccc(C(N)=O)cc1 +CCN1CC(C(=O)Nc2csc(N3CCCCC3)n2)CC1=O +CC(NC(=O)c1csc2ccccc12)C1CCCO1 +c1cncc(CNCCc2ccc(-n3cccn3)cc2)c1 +C=CCOC(=O)c1ccc(NC(C)=O)c(SC)c1 +Cc1cccc(NC(=O)N2CCC(Cn3nc(C)cc3C)CC2)c1 +C#CCNC(=O)c1ccc(=O)n(Cc2csc(-c3ccoc3)n2)c1 +O=C(C1CC1c1ccc(Cl)cc1)N1CCC(O)(C(F)(F)F)CC1 +CC(NCc1ccccc1)C(=O)Nc1ccccc1C#N +O=C(CN1CCOCC1)NC12CC3CC(CC(C3)C1)C2 +O=C(COc1ncnc2sccc12)Nc1ccc2c(c1)CCC2 +N#CCc1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 +Cc1cc(C)n(C(=O)c2cn3cc(Cl)ccc3n2)n1 +O=C(Nc1ccc2ccccc2c1)C1CC(=O)N(c2ccccc2)C1 +COc1cccc(C(=O)Nc2ccc(S(N)(=O)=O)c(C)c2)c1 +O=S(=O)(c1cccc(Cl)c1)N1CCC(O)CC1 +Cc1ccc(C)c(-n2c(C)nnc2SCC(=O)N2CCOCC2)c1 +CC(NC(=O)NCC(=O)N1CCCC1)c1ccc2ccccc2c1 +Cc1ccc(CNc2nc3ncc4c(c3c(=O)[nH]2)CCC4=O)cc1 +C=CCNc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccc(F)cc1 +CCc1ccc(NC(=O)C2CCCN(c3ncccn3)C2)cc1 +CC(=O)NCCNc1ncc(Br)cc1N +Cc1ccc(C(=O)OCC(=O)Nc2ccc(C(N)=O)cc2)cc1C +O=C(COC(=O)c1ccc(O)cc1)Nc1ccccc1 +CCc1nnc(-c2cn(CC(=O)NC(C)CC)c3ccccc23)o1 +CC(C)(C)c1ncc2c(n1)CN(c1cc(C(F)(F)F)ccn1)C2 +OC1CN(Cc2cc3ccccc3o2)Cc2ccccc21 +CC(CC(=O)NCC1CCOC1)S(=O)(=O)c1ccc(F)cc1 +CN(C)C(=O)CN(C)C(=O)c1cc(F)c(F)cc1Cl +COc1cccc(OC)c1OCCc1ccc(CO)cc1 +N#Cc1ccc(OC2CCC(NC(=O)c3ccc[nH]c3=O)CC2)nc1 +CCc1cccc(NC(=O)c2ccc(Cn3ccnc3)cc2)c1 +O=C1CCCN1c1cccc(-c2csc(N3CCOCC3)n2)c1 +COc1ncnc2c1[nH]c1ccc(Br)cc12 +CCc1cc(OC)c(OC)cc1C(=O)N1CCOCC1 +COc1ccc(N2CC(C(=O)Nc3cc(C)on3)CC2=O)c(OC)c1 +Cn1cc(N2CCN(C(=O)C3OCCc4ccccc43)CC2)cn1 +CC(O)(CNS(=O)(=O)c1ccc2ccccc2c1)C1CC1 +Cc1nc(C)c(C(=O)N2CCN(c3ccccc3Cl)C(=O)C2)o1 +CCOc1ccc(C(=O)Nc2ccccc2N(C)C)cc1OC +CC(=O)Nc1nc(C(=O)N2CC3CCCC3C2)cs1 +Nc1ccc(Cl)c(S(=O)(=O)NC2CCCCCC2)c1 +COCCCNC(=O)NC1CCN(S(C)(=O)=O)CC1 +O=C(c1cc2c(F)cc(Br)cc2[nH]1)N1CCOCC1 +COCC1CN(C(=O)c2cc(C)on2)Cc2cn(CC3CC3)nc21 +CSc1cc(C(=O)Nc2ccnn2CC(C)C)ccn1 +CC(C)c1nc(CSc2nncn2C(C)C)cs1 +Cc1ccccc1C(=O)NC(C(=O)Nc1ccc(CC#N)cc1)C(C)C +CCOc1cc(C)ccc1NC(=O)Cn1ccc(=O)n(C)c1=O +Cc1cc(NC(=O)CCN2c3ccccc3CC2C)no1 +Cc1c(NC(=O)c2cnccn2)c(=O)n(-c2ccccc2)n1C +COC(=O)c1sc2nc(C)nc(NC(C)c3ccco3)c2c1C +C=CCN(C)C(=O)c1nc(-c2ccoc2)n(-c2ccc(C)cc2)n1 +CCCN(C)C(=O)Nc1ccc(Br)cc1F +Cc1ccc(NC(=O)N2CCC(O)(C(F)(F)F)CC2)s1 +Cc1n[nH]c(C)c1CNC(=O)c1cc(F)c(F)c(F)c1 +COc1cc(C)c(C(=O)Cn2cc(N)cn2)cc1Cl +CCN(Cc1nc(C)no1)C(=O)C1COc2c(cccc2OC)C1 +COc1ccccc1OCCC(=O)NC1CCC(O)CC1 +COC(=O)C1CC(Oc2cccc(OC(F)(F)F)c2)CN1 +CCC(C)C(C)Nc1c(C#N)c(=O)n(C)c(=O)n1C +COC(C)CCC(=O)Nc1ccnc(C(C)(C)C)n1 +CCCOc1ccc(C(=O)Nc2nccs2)cc1 +Cc1nc(C)n(CC(C)C(=O)NCc2ccccc2)n1 +CCN1CC(C(=O)NCCc2nc(C(C)C)no2)CC1=O +O=C(NCCc1ccccc1Cl)c1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)c2cc(C)nc3c2cnn3C(C)C)c(F)c1 +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)c1cccs1 +CCC(C)c1ccc(S(=O)(=O)Nc2ccn(C)n2)cc1 +O=C(Nc1ccc(-n2cccn2)cc1)c1ccccc1F +O=C(c1ccc(F)cc1)N(Cc1cccnc1)Cc1ccco1 +O=C(NCCCO)Nc1ccc(OC(F)F)c(F)c1 +Cc1csc(=O)n1CC(=O)Nc1nc2cc(Cl)ccc2o1 +CCc1noc(CNc2ccccc2CCC(F)(F)F)n1 +Cc1ccc(Cl)cc1NC(=O)C(C)OC(=O)c1cccnc1 +O=S(=O)(Cc1ccccc1)Nc1cccc2ncccc12 +COC(=O)c1c(NC(=O)Cc2ccccc2OC)sc(C)c1C +CC(NC(=O)NCCOc1ccc2c(c1)OCO2)C1CCCO1 +O=C(Nc1nc2c(s1)COCC2)c1cc(-c2cccs2)n[nH]1 +O=C(CN1CCN(c2ncnc3ccsc23)CC1)N1CCOCC1 +CCOc1ccc(C(=O)Nc2ccc(F)c(F)c2F)cc1OC +Cc1ccnc(NC(=O)COc2ccc(Cl)c3cccnc23)c1 +O=C1CCC2(CCCO2)CCN1CCOCc1ccccc1 +CC(NC(=O)C12CC3CC(CC(O)(C3)C1)C2)c1ccc2c(c1)OCO2 +CC(C(=O)N1CCc2[nH]ncc2C1)n1cnc2ccccc2c1=O +N#CCn1nc(Cc2cccc(F)c2)c2ccccc2c1=O +O=S(=O)(NCC(O)c1ccc2c(c1)CCO2)c1cccs1 +CNC(=O)CCC(C)(C)NC(=O)c1cc(S(N)(=O)=O)ccc1F +COC(=O)c1ccc(F)c(NCc2noc(-c3ccoc3)n2)c1 +Cc1cc(C(=O)Nc2ccc(NC(N)=O)cc2)[nH]n1 +CC1CCC(NC(=O)C(NC(=O)c2cccs2)C(C)C)CC1 +C=CCNC(=O)Cc1csc(-c2ccc(C)cc2)n1 +CC(C)(C)Oc1cc(CNC(=O)Cc2cc(F)ccc2F)ccn1 +CCN(CC)C(=O)Nc1ccc(C(=O)Nc2ccccc2OC)cc1 +CS(=O)(=O)NCC#CCOc1cccc2ccccc12 +Nc1cccc(OS(=O)(=O)c2ccc3[nH]c(=O)cnc3c2)c1 +CC(C)(C)CC(=O)N(Cc1ccco1)CC1CCCO1 +CSc1ccc(-c2nnc(NC(=O)c3cccc(F)c3)o2)cc1 +CCCN1CCN(C2CCN(C(=O)C3CCCC3)CC2)C1=O +COCc1nc2c(N)cccc2n1C(C)C(=O)OC +O=C(Cc1c(F)cccc1Cl)Nc1cccc2cn[nH]c12 +Cc1nc2cc(C(=O)OCCCc3ccncc3)ccc2n1C +CC(c1ccncc1)N(C)C(=O)c1csc(-c2ccco2)n1 +O=c1c2cc(Cl)ccc2ncn1Cc1ccccc1F +CN(C)C(=O)c1ccc(NCC(=O)N2CCCCC2)cc1 +COCc1noc(CN2CCCC(C)(c3ccccc3)C2)n1 +CC(OCC(F)(F)F)c1nc(CC(=O)NC2CCCC2)no1 +CCC(CC)N(C)C(=O)c1cccc(NS(C)(=O)=O)c1 +O=C1Cc2cc(NC(=O)c3cc(-c4cccs4)n[nH]3)ccc2N1 +CC(CCc1ccco1)NS(=O)(=O)c1ccc(F)c(F)c1F +CCCN(CC(F)F)S(=O)(=O)c1cccc(Cl)c1C#N +CC1Oc2ccccc2OC1C(=O)Nc1ccc(F)cc1 +COc1ccc(C(C)C)cc1C(=O)CCCC(=O)N(C)C +O=C(Nc1ccccc1SCc1ccsc1)c1ccncc1 +CS(=O)(=O)N1CC(C(=O)Nc2cccnc2)Oc2ccccc21 +CCOC(=O)c1ccc(NC(=O)CSc2nnc(C)o2)cc1 +O=C(Cc1ccc(-n2cccn2)cc1)N(Cc1cccs1)C1CC1 +CCc1ccc(-n2cc(C(=O)N3CCc4ccccc4C3)nn2)cc1 +O=C(c1cccc(Oc2ccccn2)c1)N1CCCC1 +COc1ccc(C(=O)N2CCC3(CCC(=O)N(CCO)C3)CC2)cc1 +CCOc1ccc(S(=O)(=O)NCC(C)O)cc1 +CC1CCCC(NC(=O)N(C)CC(=O)NC(C)(C)C)C1 +COc1ncccc1NC(=O)CS(=O)(=O)NC1CCC(C)CC1 +O=C(Cc1ccc2c(c1)OCCO2)N1CCN(c2nccs2)CC1 +O=C(NC1CC1)C1CCCN1C(=O)CCc1ccccc1O +Cc1ccc(NC(=O)CCn2ccnc2-c2ccncc2)cc1C +Cc1ccc(-c2ccc(C(=O)NCC(C)O)o2)cc1C +COc1ccccc1-c1ccc(NCCNC(C)=O)nn1 +Cc1nccc(CNC(C)c2cccc(OC(F)F)c2)n1 +Cc1cc(CNC(=O)NCC(C)(C)c2ccncc2)ccc1F +Cc1cccc(NC(=O)c2cc(Br)c[nH]2)c1 +CC(=O)Nc1ccc(C(=O)Nc2ccc3nc(C)sc3c2)cc1 +C=CCOCCCC(=O)N1CC(C)(C)Sc2ccccc21 +O=C(Nc1cccc(F)c1)C1CCN(C(=O)C2CC2)CC1 +O=C(C1CCCO1)N1CCN(Cc2ccc(Cl)cn2)CC1 +CCc1nc(CC(=O)OCc2coc(-c3ccccc3)n2)cs1 +COc1cc(C(=O)Nc2ccc(F)cc2N)cc(OC)c1OC +CCC(=O)Nc1nc2ccc(NC(=O)c3ccncc3)cc2s1 +CC(=O)Nc1cc(NC(=O)CCNC(N)=O)ccc1F +COc1ccc(C(=O)NCc2nc(-c3ccccc3C)no2)cc1 +CCCCn1c(=O)[nH]c(=O)c2c1nc(CN1CCOC(C)C1)n2C +CC1CCN(C(=O)c2ccc(NC(=O)Cn3cnnn3)cc2)CC1 +CCOc1ccc(CC(=O)N2CCc3[nH]ncc3C2)cc1 +COCc1cnc2c(c1SCC#N)c(=O)n(C)c(=O)n2C +O=C(COc1ccc(Cl)c2cccnc12)N1CCC(O)CC1 +COc1ccccc1CC(C)NC(C)c1ccco1 +COc1cncc(N2CCN(c3nc(C4CC4)ns3)CC2)n1 +COCc1noc(CCNC(=O)c2cnn(C(C)C)c2)n1 +O=C(N1CCOCC1)N1CCN(c2cccc(C(F)(F)F)c2)CC1 +COCC(NC(=O)N1CCOCC1C1CC1)c1ccco1 +Cc1ccc(C2C3=C(COC3=O)Nc3[nH]nc(C)c32)cc1C +Cc1ccc2[nH]cc(C(=O)CN3CCC(C(N)=O)CC3)c2c1 +Cc1nn(C)c2nc(N(C)CC3COCCO3)sc12 +Cc1csc(SCc2ccc3ccccc3n2)n1 +CCN(Cc1ccco1)S(=O)(=O)c1ccc(OC)cc1 +CCOCC(=O)Nc1ccc(-n2c(C)nc3ccccc3c2=O)cc1 +Cc1cc(Nc2ccn(Cc3ccccn3)n2)n2ncnc2n1 +Cc1cccc(N(CCC(N)=O)Cc2cccc3c2OCCO3)c1 +O=C(NCC(O)c1cc(F)ccc1F)C1CCCCC1 +Cc1ccccc1OCC(C)NS(=O)(=O)N(C)C +Cn1ccnc1S(=O)(=O)Cc1csc(-c2ccsc2)n1 +CN(Cc1ccco1)C(=O)C1(C)Sc2ccccc2N(C)C1=O +Cc1nc(C2CCCCCN2C(=O)Nc2cc(C#N)ccc2C)no1 +COc1c(Cl)cccc1NC(=O)c1ccc(-n2ccnc2)nc1 +COC(=O)c1ccccc1NC(=O)Cc1noc(C(=O)NC(C)C)n1 +Cc1cccc(-c2noc(CN(C)C(=O)Cc3ccccc3O)n2)c1 +c1ccc(-c2noc(CN3CCOCC3C3CC3)n2)cc1 +CCc1nc(CN2CCN(c3ncnc4cc(F)ccc34)CC2)no1 +CCC(C)Nc1ncnc(N(CC)CCO)c1N +COc1ccccc1NC(=O)Cn1cnc(C)cc1=O +O=C(CC(F)(F)F)NCc1cccc(NC(=O)C2CCCC2)c1 +CCC(=O)NC(Cc1cc(=O)[nH]c(C2CCC2)n1)c1ccc(F)cc1 +COc1ccc(OC(=O)CCc2cscn2)cc1C +Nc1cc(Cl)ccc1N(CCO)C1CCCC1 +CCOc1ccc(Cl)c(C(=O)N(C)CC(N)=O)n1 +CC(C)(C)OC(=O)NCCC(=O)Nc1ccc(C#N)cc1 +COc1ccc(-c2nc(C)c3c(n2)CCCC3)cc1N +Fc1ccc(-n2ncc3c(NCC4CCCO4)ncnc32)cc1 +COC(=O)c1c(-c2ccc(OC)c(OC)c2)noc1N +Cc1ccc(C(CN2CCOCC2)NC(=O)c2cc(C)oc2C)cc1 +Cc1noc(C2CCC3C(CCN3C(=O)N3CCCC3)O2)n1 +Cn1c(CSc2nc(-c3ccccc3)cs2)cc(=O)n(C)c1=O +O=C(c1cc2cccc(Br)c2o1)N1CCC(O)C1 +COc1cccc(NC(=O)CN2C(=O)COc3ccc(Cl)cc32)c1 +CCN(Cc1ccccc1)C(=O)CCn1ccccc1=O +Cc1ccc(-c2cc(C)n(C)c(=O)c2C#N)c(C)c1 +CCOc1cccc(CN2CCOC3(CCCC3)C2)c1 +Oc1ccc(-n2nnnc2SCC2CCCCO2)cc1 +COC(=O)Cn1cnc2c(-c3cccc(F)c3)csc2c1=O +CCCCC(=O)Nc1ccc(NC(C)(C)CO)nc1 +Cc1cc(C(=O)NCCCN2CCCC2=O)c(C)o1 +COC(=O)c1n[nH]cc1CN1CCN(Cc2cccc(F)c2)C(=O)C1 +Cc1cc(N)c(Br)c(C(F)(F)F)c1 +O=C(NC1CCCc2ccccc21)c1c(F)cccc1Cl +COC(=O)C1=C(C)N(C)C(=O)CC1c1ccc(OC)cc1OC +Cc1cn(-c2ccc(CNC(=O)c3ccc(F)cc3F)cc2)cn1 +O=C(CC1CCN(C(=O)NCC2CCCO2)CC1)N1CCOCC1 +CNc1ncc(C(=O)N2CCCCC2CCNC(=O)COC)cn1 +CCOC(=O)C(C)NC(=O)c1cc(Cl)ccc1N +Cc1cc(OC(C)C(=O)N(C)CC(=O)NC(C)C)ccc1Cl +Cc1ncc(CNS(=O)(=O)N(C)C2CCCCC2)s1 +COc1cc(C)c(C)cc1C(=O)CCC(=O)NC1CCCC1 +CCN1C(=O)Cc2cc(NS(=O)(=O)c3ccc(C)cc3)ccc21 +Cc1ccc(NCc2c[nH]nc2C(C)(C)C)cc1S(C)(=O)=O +O=C(CCc1ccsc1)Nc1nc(-c2cccnc2)cs1 +Nc1nc(C(F)(F)F)n2c(n1)nc1ccccc12 +Cc1cc(C)c2c(CC(=O)N(CCC#N)Cc3cccnc3)coc2c1 +CN(CCCNC(=O)NC1CCCCC1)S(C)(=O)=O +CC(=O)NC(C)(C)c1noc(-c2ccc(-c3nc(C)cs3)cc2)n1 +O=c1[nH]c(CO)nc2scc(-c3ccc(F)cc3)c12 +CSc1ccccc1NC(=O)CN(C)C(=O)c1ccc(C)c(C)c1 +CC1CCN(C(=O)c2oc3ccccc3c2NC(=O)C2CC2)CC1 +O=C(c1cc2ccccc2oc1=O)N1CCCCC1 +COCc1cc(CNC(=O)Nc2cccc(N(C)C)c2)n[nH]1 +Cc1ccc(-c2nnn(C(C(=O)N(C)C)C(C)C)n2)cc1 +Nc1ccc2nnc(SCC(=O)Nc3ccccc3F)n2c1 +O=C1CC(c2nc(C3CC3)no2)CN1c1cccc(Cl)c1F +NS(=O)(=O)c1ccc(Br)c(Br)c1 +O=C(NCc1cccnc1)N1CCc2sccc2C1 +COc1c[nH]c(C(=O)N2CCC3(CCCO3)CC2)cc1=O +CCOC(CC)C(=O)Oc1ccc2ccc(=O)oc2c1 +COc1ccc(-c2nnc(-c3ccc(N)cc3)o2)cc1 +CCCOc1nc(CCC)nc(NC(C)(C)C)c1N +CNS(=O)(=O)c1ccc(CNC(=O)c2ccc3c(c2)CCO3)cc1 +CCn1c(C)c(C)n2c3c(=O)n(C(C)C(C)=O)c(=O)n(C)c3nc12 +Cc1cc(C#N)c(NC2CC2)nc1-c1cccs1 +Cc1ccc(C)c(NC(=O)Cn2ccc3sccc3c2=O)c1 +Cc1cc(C)nc(N2CCCC(C(=O)Nc3ccc(F)cc3F)C2)n1 +Cc1nccn1-c1ccc(NC(=O)c2[nH]nc(C3CC3)c2Cl)cn1 +CC(NS(=O)(=O)N1CCCCC1)C(=O)NC(C)(C)C +CC(=O)N1CCN(c2cc(-c3ccc(F)cc3)nc3ccnn23)CC1 +O=c1[nH]cc(NS(=O)(=O)c2ccc(Cl)cc2)c(=O)[nH]1 +O=C(NCCCOCC1CCCO1)c1ccnc2ccccc12 +Nc1c(-c2ccccc2Br)cc[nH]c1=O +COc1ccc(NC(=O)COC(=O)c2ccc(CO)cc2)cc1Cl +Brc1ccc2c(c1)N(Cc1ccncc1)CCN2 +COc1ccccc1C(=O)NC(CN1CCCC1=O)c1ccccc1 +Cc1c(O)ccc2c(CN3CC(C)OCC3C)cc(=O)oc12 +Nc1cc(Cl)cc2c(CC(=O)NC3CCCCC3)noc12 +CSc1ccc(C(=O)N(C)Cc2ccccc2Cl)cc1 +CCNC(=O)N(Cc1ccco1)Cc1ccc(C)s1 +COc1ccccc1CC(=O)NCc1ccc(C(N)=O)o1 +N#Cc1cccc(C(=O)NCC2(N3CCOCC3)CCCCC2)c1 +COC(=O)c1ccc(OC(C)C(=O)N2CCOCC2)cc1 +COc1cc(CCNC(=O)c2ccnc(-n3cncn3)c2)ccc1C +CCC(CC)NC(=O)CCc1nnc(-c2ccc(C)cc2)o1 +NS(=O)(=O)c1cccc(NC(=O)c2ccc3ncsc3c2)c1 +CCN(Cc1noc(C)n1)C(=O)C(c1ccc(C)cc1)N(C)C +O=C(Nc1ccccc1F)c1cc2c([nH]c1=O)CCC2 +CC1Oc2ccc(NC(=O)C3(c4ccccc4)CC3)cc2NC1=O +CC(C)CC(=O)N1CCc2c(nc(-c3ccccn3)nc2N(C)C)C1 +CCc1c(C(=O)Nc2cc(C(C)C)n[nH]2)cnn1-c1ccccn1 +Cc1cccc2[nH]c(-c3cnc(-c4ccco4)nc3)nc12 +CCOC(=O)CNC(=O)c1cccc(C#CCO)c1 +O=C(NCc1ccco1)c1cnn(-c2ccccc2)c1-c1ccccc1 +COc1cc(OC)c2c(C)c(Cl)c(=O)oc2c1 +COC(=O)c1ccoc1COc1cccc(S(C)(=O)=O)c1 +Cc1cc(S(=O)(=O)NCC2CCC2)c(C)s1 +CNC(=O)c1ccc(OC)c(NCc2cccc(C(=O)OC)c2)c1 +COc1cc(N2CCC3(CCN(Cc4cccnc4)C3=O)C2)ncn1 +CC(C)n1ncc2[nH]c(-c3cc4ccccc4o3)nc21 +COc1ccccc1OCCN(C)C(=O)c1cnc2ccc(C)cn12 +CC1CCN(C(=O)CSc2nncn2C(C)C)c2ccccc21 +CC(=O)c1ccc(C(=O)NC(C)c2ccc(-n3cncn3)cc2)s1 +CCNC(=O)CN(CC)C(=O)c1cccc2[nH]ccc12 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)c1ccc2[nH]cnc2c1 +CCn1c(=NC(=O)Cc2cccnc2)[nH]c2cc(F)ccc21 +CCCNc1nc(-c2cc(C)sc2C)cs1 +Cn1cc(NCc2ccc(F)cc2F)ccc1=O +Cc1ccc(OCCCNC(=O)Nc2ccc3c(c2)C(=O)NC3)cc1 +CNc1cc(C(F)(F)F)nc(-c2ccccn2)n1 +Cc1nc(-c2ccc(OCC(=O)N3CCOC(C)C3)cc2)no1 +FC(F)(F)c1csc(COc2nnc(-c3ccccc3)o2)n1 +CC(=O)NC(CC(=O)N1c2ccccc2CC1C)c1ccccc1 +O=C1CN(C(=O)CCC(=O)Nc2ccc3cc[nH]c3c2)CCN1 +Cc1sc(-n2cnnn2)c(C(=O)Nc2cc(Cl)ccc2O)c1C +Cn1nc(S(C)(=O)=O)n(-c2cccc(F)c2)c1=O +COc1ccc(Cl)cc1C(=O)Nc1cnc(N2CCOCC2)nc1 +NC(=O)CC1CCN(C(=O)c2cc(Cl)c3c(c2)OCCO3)CC1 +CC(C)CCOC1CCCCC1NC(=O)c1ccccn1 +NS(=O)(=O)CCNC(=O)CCc1cnn(-c2ccccc2)c1 +COc1coc(C(=O)NCCc2ccc(F)cc2)cc1=O +CCc1ccc(C(=O)NC2CCCCCC2C(=O)OC)o1 +Cc1c(-c2ccccc2)sc2ncn(CC(C#N)CCC#N)c(=O)c12 +O=S(=O)(NCCc1ccccn1)c1ccc(F)cc1F +Nc1nc(-c2cccnc2)ncc1C(=O)Nc1cccc(F)c1 +COc1ccc(-c2cccn3nc(N)nc23)c(F)c1 +CCc1noc(CC)c1CNC(=O)N1CCCCCC1 +COc1ccccc1C(O)c1cc(F)c2c(c1)CC(=O)N2 +Cc1cc(C)cc(OCC(O)Cn2nc(-c3ccco3)oc2=O)c1 +O=C1NCC2(CCCN(C(=O)c3cc4c([nH]c3=O)CCC4)CC2)O1 +CCOCCC(=O)Nc1cc(C)nn1-c1ccccc1F +CCOc1ccc(-n2c(=O)c3ccccc3n3c(C)nnc23)cc1 +Cn1ncc2c(NCc3ccccc3Cl)nc(N3CCCC3)nc21 +COCCNC(=O)Nc1ccc(Oc2ccc(C#N)cc2)cc1 +Cc1ccccc1CNC(=O)NCC(=O)Nc1ccc(Cl)cc1 +Cc1ccc(Cl)cc1NCC(=O)N1CCC2(CC1)OCCO2 +NC(=O)NCCCCC(=O)Nc1cccc(N2CCCC2=O)c1 +Cc1ccccc1OCC(=O)Nc1nnc(C2CCCO2)s1 +CC(=O)N1CCN(C(=O)Cc2csc(Nc3ccccn3)n2)CC1 +COC(=O)c1cccc2c1CCCN2CC(=O)Nc1nc(C)cs1 +CCc1noc(CC)c1CC(=O)NCc1nc(-c2cccs2)no1 +CC(OC(=O)CSc1nnnn1C1CCCC1)c1ccccc1 +CC(C)C1(C)CC(=O)c2cc(Br)cc(N)c2O1 +N#Cc1ccc(-c2noc(-c3cccc4c3OCO4)n2)nc1 +Cc1ccc(C(=O)N2CCN(CC(=O)NCc3ccco3)CC2)s1 +COc1ccc(C(=O)NCC(O)c2ccc(F)cc2)cc1 +Cc1ccc(C(=O)N2CCC(=O)N(CC(C)C)CC2)s1 +O=C(Nc1ncn(Cc2ccc(Cl)cc2)n1)c1ccc(F)cc1 +CC1COCCN1C(=O)COc1ccccc1N +NC(=O)c1ccccc1COC(=O)c1ccccc1F +CN(C)S(=O)(=O)c1cccc(COC(=O)c2ccoc2)c1 +O=C(Cn1ccc(C(F)(F)F)n1)NCc1cccnc1 +CCn1ncc(-c2ccccc2OC(C)C)c(C(C)=O)c1=O +CCCn1nc(C(=O)NCc2cn[nH]c2)ccc1=O +CCNC(=O)C(C)Sc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +COCCCNC(=O)c1ccc(-c2ccccc2)nc1N +Cc1ccc(N2CC(C)Cn3c2nc2c3c(=O)[nH]c(=O)n2C)cc1 +C=CCn1cc(-c2nc3c([nH]2)c(-c2cccnc2)nn3C)c(C)n1 +CC(C)n1ncc(NC(=O)c2ccccc2)c(N2CCOCC2)c1=O +NC(=O)Cc1ccc(NC(=O)Nc2ccccc2)cc1 +O=C(CO)N1CC2CN(c3ccccc3)C(=O)C2C1 +CC(CNC(=O)c1cccc(-c2ncn[nH]2)c1)Nc1ccccc1 +O=C(Nc1ccccc1)c1ccc(S(=O)(=O)C(F)F)cc1 +CCn1c(C)ccc(C(N)c2ccc(OC)cc2OC)c1=O +Cc1ncc(C(C)NC2CCN(c3ncccc3Cl)C2)s1 +COc1ccc(-c2cc(-c3cc(=O)[nH]c(-c4cccnc4)n3)no2)cc1 +Cc1noc(C)c1CC(C)NC(=O)Cc1c[nH]c2c(C)cccc12 +COc1ccc(CNC(=O)c2ccnc3ncccc23)c(OC)c1 +COC(=O)CSc1nnc(-c2cc(-c3ccc(C)cc3)n[nH]2)n1N +COC(=O)Cn1c(C(C)=O)nc2ccc(F)cc21 +COC(=O)c1c(C)[nH]c(C(=O)Cn2nnc(-c3cccs3)n2)c1C +Cc1cc(NC(=O)N(C)CCOc2ccc(Cl)cc2)no1 +Cc1cc(CN(C)C(=O)C2CCOc3ccccc32)no1 +CC(C)N(Cc1ccccc1)C(=O)COc1ncnc2sccc12 +COc1ccc(NC(=O)c2ccc(OC)c(Cl)c2)cc1N +Cn1ccnc1C(NC(=O)CC1CCCC1)c1ccc(F)cc1 +CNC(=O)c1ccc(NC(=O)COc2cccc3c2CCC3=O)cc1 +CCOc1ccc(C(=O)NCc2ccc(Cl)cc2)cc1OC +CCC1Nc2cc(Br)c(F)cc2NC1=O +O=C1CCC(COC(=O)c2ccc3c(c2)CCCC3)N1 +Brc1ccc2nc(-c3cccnc3)oc2c1 +COc1ccc2c(c1)nc(-c1ccccc1F)n2CCO +COc1cccc(Oc2ccc(NC(=O)c3cnccn3)cc2)c1 +COC(=O)NCCCC(=O)N1CCc2cc(F)ccc2C1 +Cc1csc(NC(=O)c2ccc(N3CCCC3)nn2)n1 +CCN(CCO)C(=O)C1CC(=O)N(c2ccc(F)cc2F)C1 +Cc1nc(C(N)c2ccccc2F)n2ccccc12 +O=C(CCn1nnc2ccccc2c1=O)Nc1ccc2c(c1)CCC2 +CCOc1ccc(NC(=O)N(C)C(C)CC#N)cc1Cl +CCC(C)(C#CCN1CCOCC1)OCCC#N +CC(CO)(CO)C(=O)NCC1(c2ccc(F)cc2)CCOCC1 +CC(C)C(C)NC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +N#CCc1ccc(OS(=O)(=O)c2ccccc2C#N)cc1 +Cc1cc(=O)n(C)cc1NC(=O)C1COc2ccccc21 +Cc1cccc(CNS(=O)(=O)c2ccc3c(c2)OCCO3)n1 +COc1cccc(CC(=O)NCCC(O)C(C)(C)C)c1 +NC(=O)COC(=O)C1(c2cccc(F)c2)CCC1 +Cc1noc(C)c1CC(=O)OCCOc1ccc(C#N)cc1 +Nc1c(-c2ccc3c(c2)OCCO3)nc2c(F)cccn12 +CC(CNC(=O)N1CCCC2(C1)OCCO2)c1ccsc1 +CC(NC(=O)CCC(=O)c1ccccc1)c1nc2c(s1)CCCC2 +CN(C(=O)Nc1cc(S(C)(=O)=O)ccc1F)C(C1CC1)C1CC1 +CC(=O)c1ccc(NC(=O)CSc2nc3nc(C)ccc3o2)cc1 +Cc1ccc(CN(C)C(=O)c2cc3c(s2)CCC3)o1 +CCN(C(=O)CSc1nc(C)c(CC(N)=O)s1)C1CC1 +CNC(=O)c1cccc(OC(=O)c2ccnc3ccccc23)c1 +CSc1nc(OCC(=O)Nc2nccs2)c2ccccc2n1 +CC(=O)Nc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1 +Cc1ccc(C(=O)NCC(O)Cc2ccc(F)cc2F)c(=O)[nH]1 +CCc1nc(CN2CCN(C(=O)NCC(F)(F)F)CC2)no1 +Nc1nc(-c2cccnc2)ccc1C(=O)NC1CCCCCC1 +Cn1ncc2c(NCCc3cccs3)ncnc21 +CN(C)C(=O)CNC(=O)c1ccc(NC2CC2)nc1 +CCCCS(=O)(=O)N1CC(c2nc(-c3ccco3)no2)C1 +CC(OC(=O)Cn1cnc2c(oc3ccccc32)c1=O)C(=O)N(C)C +Cc1c(C(=O)NCCO)cnn1Cc1ccccc1 +CC(=O)Nc1cccc(C(C)NC(=O)c2cc3ccccc3[nH]2)c1 +N#Cc1cc(C#N)c(SCC2COc3ccccc3O2)nc1N +CCS(=O)(=O)N(CCO)c1ccc(C(F)(F)F)cc1 +CN(Cc1ccccn1)C(=O)NCC(C)(C)c1ccncc1 +COC(=O)c1cc(CNC(=O)c2ccccc2)ccc1OC +O=S(=O)(c1ccc(Cl)cc1Cl)n1ccnc1 +Cc1ccccc1CN(C)C(=O)C1Cc2ccccc2S1 +CCOC(=O)c1cc(N)ccc1NCCC(F)(F)F +Cc1ccc2ncc(C(=O)N(C)CCc3ccc(F)cc3)n2c1 +CC(C(=O)N(C)CC(=O)Nc1nc2ccccc2s1)n1cccn1 +CC(C)n1nccc1NC(=O)N(C)Cc1cccc(Cl)c1 +COCc1cncc2c1CCN(Cc1ccc(C)s1)C2 +N#Cc1cc(N)ccc1NS(=O)(=O)N1CCCC1 +COc1ncnc2c1CN(Cc1c(C3CC3)nc3sccn13)CC2 +Cc1cnccc1-n1nc(C(C)C)nc1-c1cc(C#N)c(=O)[nH]c1C +Cn1cc(C(N)=O)cc1C(=O)Oc1ccc(-n2cnnn2)cc1 +CCOc1ccc(N2CCN(CC(=O)N3CCCC3)C2=O)cc1 +CCc1cccc(NC(=O)NCc2cccc(S(=O)(=O)NC)c2)c1 +CC1CCOC1C(=O)NCC1(c2ccc(F)cc2F)CC1 +CC1CC(C)CN(S(=O)(=O)N2CCN(C(=O)N(C)C)CC2)C1 +CC(C)n1nccc1NC(=O)c1cccc(Br)c1 +Cc1nn(C)c(C)c1NC(=O)c1cc(-c2ccccc2)[nH]n1 +CC(NC(=O)c1nn(C)cc1Cl)C(=O)N1CCCCC1 +Cc1ccnc2nc(C(=O)Nc3ccc(Br)cc3)nn12 +O=C(NCC1CCc2ccccc2N1)Nc1cccnc1 +N#Cc1ccccc1Cn1cnc2ccc(Br)cc2c1=O +Nc1ccc(C2Nc3ccc(Br)cc3S2)cc1 +O=C1Nc2ccc(CO)cc2OC1c1ccccc1 +COC(=O)c1cc(S(=O)(=O)C(C)C)c(S(C)=O)s1 +CC(=O)N1CCCC1C1CCCN1C(C(N)=O)c1ccccc1 +CC(C)N(C)c1ccc(NC(=O)C2CC=CC2)cc1F +CCCCC1CCC(C(=O)N2CCC(CO)C2)CC1 +CCc1cccc(NC(=O)c2ccc(NC(C)=O)cc2)c1 +Cc1csc(C(C#N)C(=O)CCc2ccc(F)c(F)c2)n1 +CCCn1cc(NC(=O)CNC(=O)C2CC2)ccc1=O +CCOC(=O)c1c(O)cc(Br)cc1F +CC(=O)Nc1ccc(S(=O)Cc2cn3cccc(C)c3n2)cc1 +CC(C)C(=O)N1CCC(C(=O)Oc2ccc(C#N)cc2)CC1 +O=S(=O)(NCC#CCOc1cccnc1)c1ccccc1F +C#CCNC(=O)NC1CCN(c2c(F)cccc2F)C1 +COc1cc2c(cc1OC)C1=NCN(Cc3ccccn3)C(=O)C1=N2 +CCC(C)C(=O)NC1CCC2CCC(C(=O)NCCO)N2C1=O +Cc1ccc(C)c(CS(=O)c2ccc(N)cc2)c1 +CCC1CCC(N(C(=O)c2ccc(OC)c(OC)c2)C2CC2)CC1 +Cc1occc1-c1nc(N2CCOCC2)ncc1-c1ccncc1 +CNS(=O)(=O)c1ccc(C(=O)N(C)Cc2ccc(O)cc2)cc1 +Cc1c(C(=O)OC(C)C)sc2ncnc(NCCCO)c12 +O=C(NCc1ccco1)c1ccc(-c2csnn2)cc1 +CCc1nnc(NC(=O)NCCc2cccc(C(=O)OC)c2)s1 +CC(C)CN(Cc1cccc(Cl)c1)C(=O)c1nccn1C +C=CC(C)Sc1nnc(-c2cccs2)n1CCC(N)=O +COc1cccc(C2CC(c3ccc(F)cc3)Nc3ncnn32)c1 +CCN(C(=O)CNc1cccc(C(=O)NC(C)C)c1)c1ccccc1 +NC(=O)c1csc(C(=O)Nc2ccc(Cl)cc2)c1 +CCOC(=O)C1CCCN(C(=O)c2cnn(-c3ccncc3)c2C)C1 +COC(=O)C(NS(=O)(=O)c1ccc(C)s1)c1ccccc1 +c1ccc2c(c1)CCN(c1ncnc3[nH]ncc13)C2 +Cc1c(Cl)cccc1NS(=O)(=O)c1cn[nH]c1 +CCOC(=O)c1cnc2ncnn2c1C(=O)OCC +COCCN(C)C(=O)c1cc(NC(C)=O)ccc1O +O=C(NCCc1ccccn1)Nc1cccc2ncccc12 +COCCn1c(SCCC#N)nc2sc3c(c2c1=O)CCCC3 +CC(=O)NCCNCC(=O)c1ccc(Cl)cc1 +CCc1c(C)nc(SCC(=O)Nc2ccc(OC)cc2)[nH]c1=O +CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc1cn[nH]c1 +CCC(NC(=O)COc1ccccc1)c1ccc(C)cc1 +CCS(=O)(=O)c1ccc(Cl)c(C(=O)NCc2ccccc2)c1 +COc1ccc(CCC(=O)Nc2cccc(F)c2)cc1OC +CCOCCCC(=O)N(CC)c1ccc(F)c(F)c1 +O=C(Nc1ccncc1)c1occc1CSc1ccccc1 +COc1cccc(CNC(=O)c2ccc3c(c2)nc2n3CCCC2)c1 +CC(C)COC1CCN(C(=O)NC(C)c2ccccc2)CC1 +CCCCN1C(=O)C(CC(=O)NCCC)Sc2ncccc21 +Cc1cc(CNc2nc(CCc3ccccc3)nc3c2cnn3C)no1 +Cc1cc(C)cc(C(=O)NC2C3CCOC3C2(C)C)c1 +Cc1ccc(C#N)cc1NCc1nccn1C(F)F +O=C(COc1ccccc1F)NCCc1ccsc1 +CCOCCNc1cc(CC)nc2c(C)c(C)nn12 +CCNC(=O)c1ccc(N2Cc3cnc(CC(C)C)nc3C2)nc1 +CCOCCCNC(=O)C(C)N1CCCC2(C1)OCCO2 +CCC(=O)N(CC)Cc1nccn1Cc1cccc(OC)c1 +COC1CCN(C(=O)c2c(C)nc(-c3ccco3)nc2SC)CC1 +CCS(=O)(=O)N1CCC(C(=O)N(C)Cc2ccccc2)CC1 +CCOC(C)C(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +Cc1csc(CCCNC(=O)Nc2cnccc2C)n1 +CC(C)COc1cccc(CNC(=O)N2CCC(C(N)=O)CC2)c1 +O=C(NCCCc1nc2ccccc2s1)c1ccc2c(c1)OCO2 +Cc1cc(CNC(=O)c2ccc(S(=O)(=O)NC3CC3)cc2)c(C)o1 +CC(=O)c1cc(C(=O)N2CCC(CO)CC2)n(C)c1 +COCc1cccc(S(=O)(=O)NCc2nc3ccccc3n2C)c1 +CC1CCN(C(=O)CSc2n[nH]c(N)n2)CC1 +COC(=O)c1ccccc1NC(=O)c1cc2c([nH]c1=O)CCCC2 +Cc1c(Cl)c(-c2nnc(-c3ccccc3)o2)nn1C +CCc1ccc2oc(=O)cc(Cn3ccnc3)c2c1 +O=C(CSc1ccc(F)cc1)Nc1cccc2cccnc12 +CCC(Oc1ccc(C)cc1)C(=O)Nc1ccon1 +COc1ccc(C2CC(=O)c3c(C)nc(N)nc3C2)cc1OC +COc1ccc(C(=O)c2c(C)[nH]n(-c3ccccc3)c2=O)c(OC)c1 +C=CCS(=O)(=O)c1ccc(N2CCCC2=O)cc1 +Cc1ccc(CNC(=O)c2noc3c2CCc2sccc2-3)o1 +CC(=O)c1sc2c(c1N)c(=O)[nH]c(=O)n2Cc1cccs1 +CCCCN(C)S(=O)(=O)N1CCC(c2nncn2C)CC1 +COC(=O)N(C)CC(=O)Nc1cc(F)ccc1C +Cc1ccc(-c2ccc(=O)[nH]n2)cc1S(=O)(=O)NC1CCCCC1 +CC(C)NC(=O)C(C#N)Cc1cccc(Br)c1 +COc1ccc(-c2c(N)n[nH]c2-c2cccc(C)c2)cc1OC +N#Cc1ccc(NC(=O)COC(=O)CC2CC3CCC2C3)cc1 +COc1ccc(-c2nnc3sc(-c4c(C)nn(C)c4C)nn23)cc1 +COc1ccc(OC)c(NC(=O)c2ccc(OC)cc2OC)c1 +Cc1cc(C2CCCN2C(=O)CCn2c(=O)oc3ccccc32)on1 +CCCCN(C)S(=O)(=O)c1cccc(C(C)=O)c1 +COCc1cccc(NC(C)C(=O)Nc2c(C)nn(C)c2C)c1 +CCOCCN1CCN(C(=O)Nc2ccc(OC)cc2C)CC1CC +CC(C)NC(=O)c1cnc(-c2cccs2)nc1N +Cc1ccccc1C(=O)N(C)Cc1nc2ccccc2s1 +CCOCC(=O)N1CC2COCC2(COCC2CCOCC2)C1 +COc1cccc2[nH]cc(CC(=O)N3CCOCC34CCCC4)c12 +CCOC(=O)CN(C(C)C)S(=O)(=O)c1ccn(C)c1 +CCOCCOc1ccc(C(=O)n2cnc3ccccc32)cc1 +Cc1c[nH]c(-c2c(-c3ccccc3)ncn2CC2CC(=O)N(C)C2)n1 +CC1Oc2ccc(NC(=O)N3CCCCCC3)cc2NC1=O +CCC(=O)NCc1ccccc1-c1ccc(Cn2ccnc2)cc1 +COC(=O)c1cccc(NS(=O)(=O)c2ccc(SC)cc2)c1 +O=C(COc1cccnc1)N1CC(Oc2ccccc2F)C1 +Cc1ccn2c(=NC(=O)CNC(=O)OC(C)(C)C)[nH]nc2c1 +NC(=O)CCn1nc(-c2ccccc2)c2ccccc2c1=O +CCCCn1c(SCC(=O)NC2CCCCC2C)n[nH]c1=O +COc1c(F)cc(NC(=O)N(C)Cc2cc(Cl)cn2C)cc1F +CC(=O)c1cccc(NC(=O)CCc2ccc3c(c2)OCO3)c1 +CC1CCC(C(N)=O)CN1S(=O)(=O)c1cc(C(N)=O)n(C)c1 +Cn1ncc(Cl)c1C(=O)Nc1cnn(CC(F)(F)F)c1 +Cc1ccc(NCc2nsc(N(C)C)n2)cc1S(C)(=O)=O +Fc1ccccc1-c1nc(Cn2ccnc2)cs1 +N#Cc1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)nc1 +CC(C)(C)NC(=O)NCCC(=O)N1CCc2nocc2C1 +c1nc(N2CCN(Cc3cc[nH]n3)CC2)c2sccc2n1 +O=C1C(Sc2nnc(CO)n2C2CC2)CCN1c1ccccc1F +O=C(Nc1ccc2c(c1)C(=O)NCC2)c1cccc(F)c1 +COc1ccc(C(=O)Nc2ccc(CC#N)cc2)cc1OC +Cc1csc(S(=O)(=O)CC(=O)Nc2ccc(Cl)cc2C)n1 +Cc1[nH]ncc1C(=O)NCCOc1ccc(C(F)(F)F)cn1 +Cc1cccc(N2CCN(C(=O)c3ccnc4ccccc34)CC2)c1 +Cc1ccn(-c2ccc(NCc3ccc(Cn4ccnc4)cc3)nn2)n1 +Cc1ccc2cc(CCNC(=O)CC(C)C)c(=O)[nH]c2c1C +O=C(Cn1cncn1)Nc1ccc(OC(F)F)cc1 +CCc1nnc(NC(=O)c2cccc3ccccc23)s1 +Cc1cc(C(=O)N2Cc3ccccc3CC2C(N)=O)c(C)n1C(C)C +CC(C)NC(=O)NCC1(c2cccc(Cl)c2)CCOCC1 +CC(CNS(=O)(=O)c1cccs1)c1nc(-c2ccccc2)no1 +Cc1ccc(OS(=O)(=O)c2cccc(-n3cnnn3)c2)c(C)c1 +O=C(Nc1cccc(-n2cnnn2)c1)c1cccc(F)c1 +Cc1ccc(NC2Nc3cc(C)nn3S2)c(C)c1 +COc1cc(CNC(=O)c2cccnc2)ccc1OCC(F)(F)F +Nc1cc(C(O)CCC(=O)NC2CCCCC2)ccc1Cl +Oc1cc(O)cc(C2NCCc3c(O)ccc(F)c32)c1 +COC(=O)c1ccc(CNc2cccc(F)c2)cc1 +CC(C)NC(=O)CCN1CCN(C(=O)c2cccs2)CC1 +Cc1ccc(Br)cc1SCC(=O)NCc1ccco1 +COc1ccc(NC(=O)Cn2cnc3sccc3c2=O)cc1 +CC(Sc1ccccn1)C(=O)Nc1cccn(C)c1=O +CN(Cc1nc2ccccc2[nH]1)C(=O)c1cnn(C)c1N +COc1ccccc1NC(=O)c1cc(-c2cccnc2)[nH]n1 +Cc1noc(C(C)Sc2nc3sc4c(c3c(=O)[nH]2)CCCC4)n1 +Cc1c(Cl)c(-c2nnc(Cc3ccc(Cl)cc3)o2)nn1C +COc1ccc(-c2cnnn2Cc2ccco2)cc1 +O=C(Nc1cnn(C2CCOC2)c1)C1COc2ccccc2O1 +COC(=O)c1nnn(-c2nonc2N)c1-c1cccs1 +Cc1ccc(-c2n[nH]c(Nc3ncccn3)n2)cc1 +C#CCN(Cc1ccn(C)c(=O)c1)C1CCc2ccccc21 +COc1ccc(CNc2ccc(F)cc2OC)cc1F +O=C(N1Cc2cncnc2C1)C12CC3CC(CC(C3)C1)C2 +Fc1ccc(CNc2c(-c3ccco3)nc3cnccn23)cc1 +O=C(Nc1cccc(F)c1)c1cc2cccnc2[nH]c1=O +Cc1sc(=O)n(CC(=O)OC(C)c2ccc(F)cc2F)c1C +NC(=O)c1cc(OC2CC2)ccc1S(N)(=O)=O +CCOC(=O)c1cc(-c2cc(Cl)ccc2SC)n[nH]1 +CCN(C)S(=O)(=O)NC(c1ccc(OC)cc1)C1CCOCC1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)c1ccc[nH]1 +Cn1c(N)nnc1SCc1ccc(F)cc1Br +CCCN(Cc1ccc(C#N)cc1)CC(O)c1ccccc1 +Cc1nc(-c2ccccn2)sc1C(=O)NC(C)CN1CCOCC1 +CN(C)S(=O)(=O)c1cccc(S(=O)(=O)NC2CCCCC2)c1 +CC(C)n1cc(Br)cc1C(=O)NCC1CCCO1 +CCN(Cc1cnc2ccccn12)C(=O)c1ccccc1OC +CNC(=O)c1ccsc1NC(=O)c1ccc2nccnc2c1 +Cc1ccc(CN2C(=O)CCC2(C)C(=O)NCCC(C)C)cc1 +COc1ccc(S(=O)(=O)Nc2ccccc2-n2cccn2)cc1C +CCN(CC(=O)N1CCOC2CCCCC21)CC(C)C#N +Cc1ncc(CNC(=O)CC(NC(N)=O)c2ccccc2C)s1 +CC(=O)Nc1ccc(C#CCNC(=O)Cc2cccs2)cc1 +CN(C)c1cccc(CNC(=O)Cc2coc(-c3ccccc3)n2)c1 +CC(NC(=O)C1CCC1)c1nc(-c2ccccn2)no1 +CCCN(CCC)C(=O)c1ccc(NC(=O)N2CCCC(O)C2)cc1 +O=C(c1ccncc1)N1CCCC2(CC(Oc3ncccn3)CO2)C1 +CCc1ccc(CN(C)C(=O)CCc2c(C)nc(C)[nH]c2=O)cc1 +CC(=O)Nc1ccc(F)c(C(=O)NC2CCCC(C)C2)c1 +CCc1cccc(NC(=O)NCc2ccc(OC)nc2)c1 +CSc1ccc(C(O)CNS(=O)(=O)c2c(C)noc2C)cc1 +CNC(=O)c1ccc(Cl)cc1NCC(=O)N1CCCCC1 +O=C(Nc1cccnc1)c1cc(F)ccc1Br +CC(C)NC(=O)N1CC2OCCN(c3cnccn3)C2C1 +Cc1ccoc1C(=O)N1CCC2(CC(OCC3CCOCC3)CO2)C1 +O=C(Cn1cnnn1)NCCc1ccc(Cl)cc1Cl +C#Cc1cccc(NC(=O)N(C)Cc2csc(C)n2)c1 +CCCS(=O)(=O)N1CCc2ccc(NC(=O)NC(C)CC)cc21 +CCN(CC(F)(F)F)C(=O)c1ccc(F)cc1F +Cc1cccc(C(=O)NCc2cccc(OCC(=O)N(C)C)c2)c1C +Cc1cc(C)cc(CCNC(=O)c2cccnc2)c1 +Cc1cccc(NC(=O)CN2CCOc3ccc(N)cc32)c1C +CC(=O)c1nnn(CC(=O)N2CCCCC2)c1-c1ccccc1 +CC(=O)c1ccc(S(=O)(=O)NC2CCC(O)CC2)cc1 +Cn1nccc1NC(=O)c1cc(N2CCCC2=O)ccc1Cl +COCC(C)NC(=O)Cc1c(F)cccc1Cl +NC(=O)CSc1nnc(-c2ccccc2)n1-c1ccc(Cl)cc1 +Cc1ccc(CNC(=O)Cc2nc(Cc3cccc(C)c3)n[nH]2)cc1 +OC(CNCc1c[nH]nc1-c1cccnc1)c1ccc(F)cc1F +CC(C)(C)c1ccc(CCC(=O)NCC(N)=O)cc1 +CCOc1cccc(NC(=O)c2csc(C)n2)c1 +O=C(Nc1ccc2c(c1)CCC(=O)N2Cc1ccccc1)C1CC1 +Cc1cccc(C(=O)N2Cc3ccccc3CC2C(N)=O)c1 +Cc1ccc(C)c(C(=O)NCc2cccc(OCC(=O)N(C)C)c2)c1 +Cc1ccc(C)c(N(C)C(=O)CNC(=O)NC2CC2)c1 +O=C(CNC(=O)c1ccc(F)cc1)Nc1cccnc1 +Cc1cc(NC(=O)Nc2cccc(C(C)C)c2)n(C)n1 +CC(C)Oc1ccc(C(=O)N(C)Cc2nnc3n2CCC3)cc1 +Cc1cccc2c(CC(=O)Oc3ccc4c(c3)CCC(=O)N4)c[nH]c12 +CCN(CC)C(=O)CSc1nnc(OC(C)C)s1 +O=C(NC1CC1)c1nnc2ccc(-c3ccncc3)nn12 +N#CCCNS(=O)(=O)c1ccc2c(c1)OCO2 +O=c1c2cccnc2ncn1Cc1cc(-c2ccco2)on1 +CC(Sc1nncn1C(C)C)C(=O)Nc1cccc2ncccc12 +Cc1csc(SCC(=O)Nc2ccccc2N2CCOCC2)n1 +Cc1ccncc1NCc1ccccc1C(F)(F)F +Cc1ncsc1C(=O)Nc1nc(-c2cccnc2)cs1 +Cc1nc(NCc2ccccn2)c2c3c(sc2n1)CCCC3 +CCOC(=O)C=C(C)NC(=O)c1c(-c2ccccc2Cl)noc1C +CCn1c(SC(C#N)Cc2ccc(C)cc2)nnc1C1CC1 +COCc1cccc(C(=O)NCC(C)Oc2ccccc2)c1 +CS(=O)(=O)N1CCC(C(=O)NCCOc2ccccc2)CC1 +Cc1cc(CN(C)c2cc(-c3ccccc3)nc3cc(C)nn23)on1 +NC(=O)CC(NC(=O)c1c(F)c(F)cc(F)c1F)C1CCOCC1 +COc1cc(C(=O)Nc2cccc(F)c2)cc(OC)c1OC +CC(=O)Nc1ccc(NC(=O)CSc2nncs2)cc1 +CC(COCC(F)(F)F)NC(=O)c1ccc(=O)[nH]c1 +NC(=O)c1ccc(NC(=O)CSc2nnc3[nH]c(=O)ccn23)cc1 +CCCCNC(=O)CS(=O)(=O)c1cccc(OC)c1 +Cc1ccc(NC(=O)C2CCCN2C(=O)c2cccc(F)c2)c(F)c1 +CC(NS(=O)(=O)c1ccc2c(c1)CCC(=O)N2)c1ccncc1 +Cc1c(CC(=O)NC2CC2)c(=O)oc2c(C)c(O)ccc12 +Cn1cc(-c2nc(COc3ccccc3F)cs2)cn1 +C=CCNC(=O)c1cc(S(=O)(=O)Nc2ccc(C)cc2)ccc1C +CC(=O)c1cn(CC2CCCCO2)c(=O)n(C)c1=O +Cc1ccc(NC(=O)CCSc2nc3nc(C)ccc3o2)cc1 +COC(=O)C(NC(=O)CC1NC(=O)c2ccccc2NC1=O)C(C)C +CC(C)CNC(=O)Nc1ccc(S(=O)(=O)N(C)C2CC2)cc1 +CCN(Cc1cnn(C)c1)C(=O)c1cc2ccccc2n1CC +O=C(Cc1ccc[nH]1)NC1CCN(C(=O)C2CCCCC2)CC1 +Cc1nnc2n1CCN(C(=O)C1CCCc3ccccc31)C2 +CC(C)CNC(=O)c1nnc2n(c1=O)CCN2c1ccc(F)cc1 +CCC(=O)N1CCC(n2nnc3ccccc3c2=O)CC1 +Cc1cc(C(=O)N2CC(C(=O)NCC3CCCO3)C2)no1 +CSc1ccc(C(=O)N(CC(F)(F)F)C(C)C(C)C)cn1 +CC1CCCN1C(=O)CC1Sc2ccccc2NC1=O +COc1ccc(-n2c(SC)nc3ccccc3c2=O)cc1OC +O=C(COC(=O)c1ccc2ccccc2n1)Nc1ccccc1Cl +Cc1ccccc1CS(=O)(=O)Nc1ccccc1N1CCOCC1 +O=C1NCCCCC1Sc1nnc(-c2ccc(F)cc2)o1 +O=C(CNC(=O)c1ccco1)OCC(=O)c1cccc2ccccc12 +COCc1ccc(C(=O)NCC(C(C)C)N2CCOCC2)o1 +CCc1n[nH]c(C(=O)NC2CC(=O)N(CC(C)(C)C)C2)c1C +O=C(Cc1cccc(F)c1F)NCCNC(=O)c1cccnc1 +O=S(=O)(c1ccc2c(c1)OCCCO2)N(CCO)CCO +COc1ccc(Nc2ncnc(N(C)C)c2N)c(OC)c1 +COC(=O)CCN(CC(C)C)C(=O)c1cn[nH]n1 +O=C(NC(O)C(=O)c1ccccc1)c1cccs1 +CCCOc1ccc(C(=O)N2CCOCC2C2CC2)cc1OCC +CC(=O)Nc1ccc(NCc2cc(Br)cs2)cc1 +COC(=O)Cc1cccc(NCc2ccsc2)c1 +O=c1cc(CNc2nccc(CCC(F)(F)F)n2)nc[nH]1 +Cc1ccc2ncc(C(=O)Nc3cc(C4CCC4)nn3C)n2c1 +CC(CCN1CCOCC1)NCc1cc(Br)cs1 +O=C(c1cscn1)N1CCCC2(CC(Oc3ccccn3)CO2)C1 +COC(=O)CCN(C)C(=O)c1c(C)cc(C)[nH]c1=O +COc1ccc(CCCNC(=O)NC(C)C(=O)N2CCCCC2)cc1 +Cc1cccc(C)c1NC(=O)CNCc1ccc(Br)cc1 +CC(C)Cc1nnc(NC(=O)c2ccc(-c3cscn3)cc2)s1 +COc1ccc2[nH]c(C(=O)NCc3ccc(F)cc3)cc2c1 +Cc1cc(-c2nc(-c3cccc(Cl)c3)no2)n[nH]1 +Cc1ccn2cc(C(=O)NCc3cccc(Cl)c3)nc2c1 +CCOCCN(C)c1cc(-c2ccccc2OC)[nH]n1 +CCc1cc(=O)[nH]c2nnc(SCC(=O)OCc3ccccc3)n12 +COC(=O)CNc1ccc(C(=O)Nc2ccccc2)cc1 +CC(C)(C)NC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +COC(=O)CNC(=O)c1ccc(Cl)cc1-n1cnnn1 +OCc1nc2cc(O)ccc2n1Cc1cccnc1 +COc1cc2c(C(=O)N(C)C)nccc2c(N)c1OC +N#Cc1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 +Cc1[nH]c2ccccc2c1C(=O)Nc1nncs1 +Cc1noc(C(C)NC(=O)Cc2coc(-c3ccccc3)n2)n1 +CC(C)NC(=O)COCc1nnc(C(=O)Nc2ccccc2)s1 +CCOC(=O)Cc1cc(C)cc(Br)c1O +Cc1cc(C)n(Cc2ccc(C(=O)N3C(C)CCCC3C)o2)n1 +COCC(C)N(C)C(=O)c1cnc2sccn2c1=O +Cn1c(=O)c2cc(C(=O)NC3CC3)sc2n(C)c1=O +CCCCn1c(SCC(N)=O)nc2c1c(=O)[nH]c(=O)n2C +COc1ccc(C(=O)N2CCOCC2)cc1NCCc1cccs1 +CN(C)C(=O)N1CCN(C2CCN(c3ccc(C#N)cc3)C2=O)CC1 +CN(Cc1cc(-c2ccncc2)no1)c1cc(C(=O)NC2CC2)ccn1 +Cc1cnc(N2CCC3OC(COCc4ccccn4)CCC32)nc1 +O=C(Cc1noc(COc2ccccc2)n1)Nc1ccccc1 +CCCCc1ccc(CC(=O)N(C)CCC#N)cc1 +Cc1nc(Oc2ccccc2)c(N)c(N2CCCC2)n1 +COc1ccc(CNc2cnn(CC(C)C)c2)c(Cl)c1OC +CCOc1ccccc1CNC(=O)Nc1ccc(F)c(C(N)=O)c1 +COc1ccc(CNc2ccc(N3CCCC3=O)cc2)cc1O +COc1ccc(C(=O)N(C)Cc2nccn2CC(F)(F)F)cc1 +CC1CCN(C(=O)c2cc(N3CCCC3=O)ccc2Cl)C1C +Cc1ccc(C(=O)Nc2nccs2)c2ccccc12 +CC(C)CC1NC(=O)C(Cc2ccccc2)NC1=O +CCS(=O)(=O)N1CCC(Nc2cccc(OC)c2)CC1 +c1coc(-c2ccccc2-c2nccn2CCn2cnnc2)c1 +COC(=O)c1ccccc1NC(=O)Nc1ccc(OC)cc1OC +Cc1cccc(C2C3=C(COC3=O)Nc3c2c(=O)[nH]c(=O)n3C)c1 +CNC(=O)Cn1cnc2c(cnn2-c2cccc(Cl)c2)c1=O +Cc1noc(C)c1Cn1c(-c2ccccc2)ccc(C#N)c1=O +Cc1nc2ccccc2n1CCCNC(=O)NC1CC1 +CC1(c2c(Cl)cc(F)c(O)c2F)COCCN1 +CC(=O)c1cn(CCC(=O)N(C)Cc2ccccc2)c2ccccc12 +CC(C)(C)OC(=O)N1CCC(N)(C(F)(F)F)C1 +CC(C)CCC(=O)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +COc1ccc(C(C)=O)cc1CC(=O)OCc1ccc(C#N)cc1 +O=C(NCC1CCCO1)c1cccnc1Sc1ccccc1 +Cc1nc2ccccc2c(=O)n1-c1ccc(N)cc1F +COC(=O)C1CC(n2cc(CO)nn2)CN1C(=O)OC(C)(C)C +CCc1ccc(NC(=O)CSc2cc[nH]c(=O)n2)cc1 +Cc1cc(Br)cnc1N1CCC2(CC1)OCC(C)O2 +Cc1ccc(CC(=O)Nc2ccc3nc(C)sc3c2)cn1 +COC(=O)C(NC(=O)c1ccc2c(c1)CCC2)c1ccccc1 +O=C(NCCCN1CCOCC1)c1cnc2n(c1=O)CCS2 +O=C(NCc1ccc(=O)[nH]c1)c1cccc(Oc2cnccn2)c1 +CCN(CC1CCOC1)C(=O)c1ccc(=O)n(-c2ccc(F)cc2)n1 +Cc1nnc2n1C(C)CN(C(=O)c1cnn(Cc3ccccc3)c1)C2 +CC(=O)N1CCC(NC(=O)CN2CCC(C)c3ccccc32)CC1 +Cc1cc(Cl)ccc1OCC(=O)NCc1nc2ccccc2[nH]1 +Cn1cc(NS(=O)(=O)c2ccccc2C(C)(C)C)ccc1=O +CC(C)Cn1nccc1NC(=O)c1cc(Br)ccc1F +CN(C)C(=O)CCNc1ccc(Cl)c(C(F)(F)F)c1 +O=C(CNC(=O)c1cccc(Cl)c1)NCC1CCCC1 +CC1C(=O)Nc2ccccc2N1C(=O)c1cnc2ccc(F)cc2c1 +CC1CC1C(=O)NCCC(=O)N(C1CC1)C1CCCc2ccccc21 +Cc1cc(C)n(-c2ncnc(Nc3ccc(C(F)(F)F)cc3)c2N)n1 +CCOCC(=O)NC(C)c1sc(-c2ccccc2F)nc1C +COc1ccc(CCNCc2cccc(F)c2)cc1OC +Cc1ccc(-c2noc(CN3CCCC3=O)n2)nn1 +COc1ccc(CNc2cnnc3ccccc23)cc1 +COc1ccc(CCCNC(=O)c2ccc(-c3cc[nH]n3)nc2)cc1 +COC(=O)C(C)Oc1ccc(CO)cc1C(F)(F)F +Cc1ccccc1C(=O)N1CCN(C(=O)c2ccc(O)cc2)CC1 +CC(C)NC(=O)C1CCN(c2ccc(-c3cccc(F)c3)nn2)CC1 +N#Cc1c(-c2ccccc2)nc2sc(C3CCC3)nn12 +CC(=O)Nc1ccc(NC(C)c2ccccc2F)cc1 +CCc1cc(C#N)c(NC(=O)c2ccc(C)nc2)s1 +O=C(C1CC=CCC1)N1CC(c2nc(-c3cccnc3)no2)C1 +Cc1c(NC(=O)c2cccs2)cccc1C(=O)Nc1nccs1 +NC(=O)c1cccc(CNC(=O)NCC2(c3ccccc3)CCC2)c1 +CCN(Cc1cccc(C)c1)C(=O)c1ccn(C)c(=O)c1 +COc1cccc(OCCN2CCNc3ccccc32)c1OC +COc1cc(CCC(=O)Nc2ccnc3ccnn23)cc(OC)c1 +O=C1CCC(C(=O)Nc2cc(Cl)ccc2Cl)N1 +O=C(NCCNc1nc2ccccc2s1)c1n[nH]c(=O)[nH]1 +CN(Cc1cc(Cl)cc(Cl)c1)C(C(N)=O)c1cccc(F)c1 +N#Cc1nc2ccccc2nc1-c1ccc2c(c1)OCO2 +N#CC(CCSc1nnc2ccccn12)NC1CC1 +COc1ccc(C(=O)Nc2ccc(C)cc2N)cc1 +CC(=O)N1CCn2nc(C(=O)N3CCCC3c3cc(C)no3)cc2C1 +COc1cccc(N2CCN(S(=O)(=O)N(C)C)CC2)c1 +Cc1nc(C2CCCC2)sc1C(=O)Nc1nc2ccc(F)cn2n1 +COc1c(O)ccc2c1C(c1cc(C)ccc1F)NCC2 +Cc1nc2ccc(NC(=O)CCn3cnc4ccccc43)cc2o1 +O=C(Nc1nc2ccc(OC(F)(F)F)cc2s1)c1cnccn1 +CC(=O)Nc1cc(C(=O)NCc2cccc3ccccc23)ccc1F +NC(=O)c1ccc(C(=O)NC2CCN(c3c(F)cccc3F)C2)nc1 +Cc1ccncc1NC(=O)Nc1ccc(OCC2CCCO2)cc1 +CCC(CO)NS(=O)(=O)c1ccc(Br)cc1Cl +Cc1nn(C)c(C)c1-c1cc(C(=O)NC2CCCC(C)C2)[nH]n1 +Cc1cc(CNc2cc(Cl)ccn2)ccc1F +Cc1cc(C)c(OCC(=O)NCCCN2CCOCC2)c(C)c1 +CCC(C)c1ccccc1NC(=O)CSc1nc(N)nc(N)n1 +Cc1c(C(=O)NCC(=O)N2CCCCC2)[nH]c2c1C(=O)CCC2 +Cc1cc(N)c2ccnc(C(=O)NCCc3ccccc3)c2c1 +Cc1nnnn1-c1cc(NCc2nnc(C3CCC3)o2)ccc1F +CCOC(=O)N1CCN(S(=O)(=O)Cc2cccc(Cl)c2)CC1 +NS(=O)(=O)c1ccc(CNC(=O)Cc2ccc(F)cc2)s1 +COCCCCCNC(=O)Nc1cc(Cl)ccc1F +CC1(OCC(=O)NCc2cccc(C(=O)N3CCCCC3)c2)CCC1 +Cc1cc(NCc2cnn(C)c2)ccc1Br +CC(NC(=O)c1cc(C2CC2)[nH]n1)c1ccc2c(c1)OCCCO2 +O=S(=O)(NCCc1ccc(-n2cccn2)cc1)c1ccccc1 +CN1CC2(CCN(C(=O)c3cn4ccsc4n3)C2)OC1=O +CC(c1ccc(S(N)(=O)=O)cc1)N(C)S(C)(=O)=O +Cc1cccc(S(=O)(=O)CCCOc2ccc(C)nc2)c1 +CCC(CC(=O)N1CCCC(c2nc(C)no2)C1)c1ccc(C)cc1 +CCS(=O)(=O)NCc1nn(C)c2c1CCCC2 +Cc1ccc(OCC(O)CNc2ccccc2)cc1 +O=C(NCCNS(=O)(=O)c1cccnc1)c1cccnc1 +O=C(N1CCc2ccccc2C1)C1(n2cnnn2)CCCCC1 +Cc1n[nH]c(-c2cccc(CNC(=O)COc3ccccc3C#N)c2)n1 +COc1ccc(CNC(=O)N2CCC(Cc3cnn(C)c3)C2)cc1C +CC(C)n1[nH]c(=O)c2c1N=C(O)CC2c1ccc(F)c(F)c1 +Cc1cc(C(=O)NC2(c3ccc4c(c3)OCCO4)CCCC2)no1 +CC1CCCN(S(=O)(=O)c2ccc(N3CCOCC3)nc2)C1 +COCCS(=O)(=O)c1ccc(C(=O)N2CC(C)CC(C)C2)cc1 +CC(CC(=O)N(C)CC(N)=O)c1ccc(F)cc1 +Cc1nc2c(N)cccc2n1CC(=O)Nc1ccccc1F +Fc1ccc(N2CCN(Cc3nnc(C4CC4)o3)CC2)cc1 +N#Cc1ccc(C(=O)NCC2CCCc3ccccc32)cc1 +CC(=O)N1CCN(C(=O)CCC(=O)Nc2ccc(C(C)C)cc2)CC1 +COC1CCN(Cc2nccs2)CC1Cc1ccccc1 +CCOCCCC(=O)N(C)C1CCN(c2ccc(Cl)cc2)CC1 +CC(=O)Nc1ccccc1OCC(=O)NCC1Cc2ccccc2O1 +COC(=O)c1ccc(Br)cc1Br +Cc1cc(C)n(CC(C)CNC(=O)NC(C2CC2)C2CC2)n1 +COc1ccc(C(O)CNC(=O)C2CCCCC2)cc1C +CCn1nc(C(C)C)cc1C(=O)N1CCCn2cncc2C1 +CC(=O)N1CCCc2cc(NC(=O)N(C)CCC(C)O)ccc21 +O=c1nc(Nc2cccc(Br)c2)cn[nH]1 +Cc1nc(SCc2nc3ccccc3n2C)sc1CC(N)=O +Cc1ccc(C(=O)N(C)C)cc1NC(=O)c1ccccn1 +NC(=O)c1nnn(-c2ccc(NC(=O)CCc3ccccc3)cc2)n1 +CCOc1cccc(NCC(=O)N(C)C(C)C)c1 +COc1cccc(CCC(=O)Nc2ccc3c(c2)CCC(=O)N3C)c1 +Cn1ncc(Br)c1C(=O)NCCc1ccccc1 +Cc1ccnc2oc(C(Cl)(Cl)Cl)nc12 +COc1cccc(NC(=O)N(Cc2ccsc2)Cc2ccco2)c1 +CCCN(CCC)C(=O)C1CCN(C(C)=O)CC1 +O=C(CCCc1ccccn1)N1CC=C(c2ccccc2Cl)CC1 +Cn1c(CNC(=O)N2CCCCC2)nnc1SCc1ccccc1 +CCc1noc(CC)c1CC(=O)Nc1cccnc1N1CCOCC1 +Cc1cc(C(=O)NC2CCCC2)ccc1NC(=O)N(C)CCC(C)O +Cc1ccc(S(=O)(=O)N2CCCCC2CCO)cc1 +Cc1ccc(C(=O)NCC(=O)N(C)CC(C)O)s1 +Cc1cc(C)c(S(=O)(=O)NCc2ncn(C)n2)c(C)c1 +Cc1csc(CCNc2cc(C3COCCN3)nc(C)n2)n1 +COc1ccc(CCNC(=O)c2cccnc2)cc1OC +Cc1ccc(C(=O)COC(=O)c2ccc(-n3cnnn3)cc2)cc1 +CC1(C)Cc2cccc(OCC#CCNC(=O)c3ccoc3)c2O1 +Cc1cc2c(cc1C(=O)N1CCOC(C(F)(F)F)C1)OCCO2 +O=C(Cn1cc(Br)ccc1=O)NCc1ccccn1 +CC(=O)c1ccc(NS(=O)(=O)c2ccccc2Cl)cc1 +COc1cc(OC)c(OC)cc1CNC(=O)Nc1cc(C)cc(C)c1 +Cc1ccc(NC(=O)c2ccc3c(c2)OCCO3)c(O)c1 +CCc1ccc(NC(=O)CNC(=O)c2ccccc2F)cc1 +CCc1nc(CS(=O)(=O)c2nnc(NCC(C)C)s2)cs1 +CCCNC(=O)Nc1ccc(C(=O)Nc2ccccc2OC)cc1 +CC(C)OCCS(=O)(=O)NCC1CCOCO1 +O=S1(=O)CCCN1CCOc1cc(Cl)ccc1Cl +Cc1ccc(C)c(S(=O)(=O)N(CCC#N)C2CC2)c1 +CCOCCOC(C)C(=O)Nc1ccc(N)cc1Cl +O=C(c1ccco1)N1CCOC(COc2cccc3ccccc23)C1 +Cc1noc(CNC(=O)C2CCN(C(=O)CC(C)C)CC2)n1 +Nc1nc(CN2CCCC2c2cccs2)nc2ccccc12 +CN(CCCNC(=O)OC(C)(C)C)C(=O)C1CC=CC1 +Cn1ccnc(NC(=O)c2ccc3c(c2)OCCO3)c1=O +O=C(c1ccc2c(c1)CCC2)N1CCN(c2ccccc2F)CC1 +CCN(C)S(=O)(=O)c1ccc(F)cc1C#CCCO +CC(C)c1cc(C(=O)NCc2n[nH]c(-c3ccccc3)n2)n(C)n1 +CCCNC(=O)N1CCC2(CCCN(Cc3cccc(C)c3)C2=O)C1 +O=C(COc1ccc(Cl)cc1)Nc1cccc(N2CCNC2=O)c1 +Cc1ccncc1NC(=O)NCC1CCOC1C(C)C +CCCOc1ccc(C(=O)Nc2nonc2CC)cc1 +CC1CCc2c(sc(=O)n2Cc2nccn2C(F)F)C1 +CC(CNC(=O)c1ccncc1)N(C)c1ccccc1 +CCOc1ccc(C)cc1C(O)CNCc1cccnc1 +CN(C)C(=O)N1CCN(C(=O)c2csc3c2CCCC3)CC1 +CCCCC1CCCC1NC(=O)CNC(=O)NC +Cc1nc2nc(N)nn2c(C)c1CCC(=O)NCCc1cccs1 +COc1cc(NCCNC(=O)Nc2ccccc2)nc(OC)n1 +C#CCN1CCN(C(C)C(=O)Nc2ccc(Cl)cn2)CC1 +CCC(O)c1cc(C)c2c(c1)C(NC(=O)C1CC1)CCO2 +Cc1ccccc1C(=O)N1CC(C(C)C)NCC1CO +CCC1c2ccsc2CCN1C(=O)c1cccc2[nH]ncc12 +CCCc1nnc2sc(NC(=O)C3CCCCC3)nn12 +Nn1c(SCCCO)nnc1SCc1ccccc1 +CCC(C)NC(=O)Cn1nnc(-c2ccccc2Cl)n1 +CCC(C)C(C)NC(=O)Cc1c(C)nc2nc(SC)nn2c1C +Cc1ncc(CNS(=O)(=O)c2ccc(F)cc2C)s1 +CCNC(=O)c1ccc(-c2ccc(OC)cc2)nc1N +O=C(CCC(=O)Nc1nccs1)N=c1[nH]c2ccccc2[nH]1 +CCOc1cccc(C2Nc3ccccc3C(=O)N2C2CC2)c1OC +CC(=O)c1c(C=CN(C)C)ncnc1C(F)(F)F +CN(CCN1CCOCC1)C(=O)Nc1cccc(Cl)c1N(C)C +COC(=O)c1ccc(CN(C)Cc2ccc3c(c2)OCO3)cc1F +O=C(c1ccc(=O)[nH]n1)N1CCN(S(=O)(=O)c2ccccc2)CC1 +COc1cccc(C2CCN2C(=O)CCc2c(C)noc2C)c1 +O=C(Nc1ccccc1)Nc1ccccc1CN1CCNC1=O +O=C(c1ccco1)N1CCN(c2ccc(Br)cn2)CC1 +Cc1nnc2n1CCN(C(=O)c1cccn(Cc3ccccc3)c1=O)C2 +COc1ccc(CC(=O)Nc2c[nH]cc(Br)c2=O)cc1 +COc1ccc(C(=O)Nc2nc3c(s2)CCC3)cc1OC +CCC(NC(=O)Cn1nc(C(F)(F)F)cc1C)c1ccc(C)cc1 +O=C1CCN(C(=O)C2CCCCC2)CCN1CC1CC1 +CCOC(=O)CCN1C(=O)C(CC)(CC)Oc2ccc(O)cc21 +COCCC(C)NC(=O)c1ccc(F)c(COC)c1 +CC(=O)NCc1ccc(-c2noc(-c3ccc(C)cc3)n2)s1 +O=C(Cc1ccc(Cl)cc1Cl)NCCNC(=O)C1CC1 +O=C(CNC(=O)c1ccoc1)Nc1cccc(Br)c1 +COc1cccc(CNn2cnnc2)c1OCc1ccccc1Cl +CCC(=O)Nc1ccc(N2CCCS2(=O)=O)cc1 +O=C1CN(Cc2ccccc2)C2(CCN(C(=O)C3CC3)CC2)N1 +Cc1cccc(C2c3cccn3CCN2Cc2ccc(C(N)=O)o2)c1 +CC(C)OCC(O)Cn1c(-c2ccccn2)noc1=O +Cn1cc(CNC(=O)NCCCOC2CCCCC2)cn1 +CCCN(CC1CC1)C(=O)Nc1cccc(C(=O)N2CCOCC2)c1 +CC(NC(=O)c1ccoc1)C(=O)NCc1cnn(C)c1 +CC(C)NC(=O)N1CCC(NC(=O)c2ccsc2)CC1 +CN(Cc1cccc(F)c1)C(=O)c1cc(C2CC2)[nH]n1 +COC(CNS(=O)(=O)Cc1cccc(Cl)c1)c1ccsc1 +O=C(Nc1cc2c(cc1Cl)OCCO2)C1CCOc2ccccc21 +O=c1cc(C=Cc2ccc(O)cc2)[nH]c2ccccc12 +CC(Sc1nnnn1C1CCOCC1)C(=O)NCc1ccccc1 +CCOc1ccc2nc(NC(=O)CC)sc2c1 +COc1c(Cl)cc(Cl)cc1C(=O)NCC1CCCO1 +Cc1ccc(CNc2cccnc2-n2cccn2)s1 +CN(CC1CCCO1)C(=O)c1cn(C)nc1C(F)(F)F +Nc1ccc2nc(-c3ccc(Cl)cc3F)oc2c1 +Cc1ccc(C(=O)NCCCN2CCCC2=O)o1 +CCC(C)n1nccc1NC(=O)C(C)Nc1ccc2oc(=O)[nH]c2c1 +CC(C)(C)NC(=O)CNC(=O)CCC(=O)c1ccc(F)cc1 +O=C(COc1ccccc1F)NCC(O)c1cccc2ccccc12 +CCn1cc(C(=O)NCCN2CCN(C(=O)C3CCCC3)CC2)cn1 +COC(=O)c1c(C)[nH]c(-c2nc(-c3ccsc3)sc2C)c1C +COc1cc(C)c(C(=O)NC2CCC(=O)NC2)cc1OC +CCC1CCCCN1C(=O)CSc1nc(-c2cccs2)n[nH]1 +Cc1n[nH]cc1CN(CCCO)Cc1ccc(Cl)c(Cl)c1 +CC(NC(=O)Cn1nnc(-c2cccs2)n1)c1ccco1 +Cc1n[nH]c(C)c1S(=O)(=O)Nc1ccc(OCC(F)(F)F)cc1 +N#Cc1ccc(Sc2nnnn2C2CCCC2)cc1 +COCC(=O)N1CCc2[nH]nc(C(=O)NCCc3ccccc3)c2C1 +O=C1C2CCCCN2C(=O)CN1CCC(=O)N1CCc2ccccc21 +COc1ccc(S(=O)(=O)NC(=O)Nc2nc(C)cc(C)n2)cc1 +O=S(=O)(c1cccs1)N(Cc1ccoc1)Cc1cccs1 +Cc1cc(CN(C)C(=O)Nc2ccc(-c3nccs3)cc2)no1 +COc1ccc(NC(=O)C2CN(C(=O)c3cccs3)C2)cc1OC +CCCCNC(=O)Cn1nc(C)c2c(C(F)(F)F)cc(C)nc21 +O=C(COc1ccc2ccccc2c1)Nc1c[nH]c(=O)[nH]c1=O +CCc1cc(N2CCC(O)(c3ccc(F)cc3)CC2)n2nccc2n1 +Cc1ccc(NC(=O)COc2ncnc3ccccc23)cc1F +COc1cc(OC)cc(C(=O)Nc2cc(C)ccc2OC)c1 +COC1CCCC(OC(=O)CCn2c(C)csc2=O)C1 +O=C(c1cccc(S(=O)(=O)NCc2ccoc2)c1)N1CCCCC1 +O=C(C1CCC1)N1CCSc2nnc(COc3ccccc3F)n21 +CCOC(=O)CC1Nc2cc(CC)ccc2NC1=O +Cn1ccc(-c2nnc(NC(=O)c3cccc(C#N)c3)o2)n1 +Cc1cn(-c2ccccc2Cl)nc1C(=O)NCc1ncn(C)n1 +N#Cc1cccc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)c1 +CN1c2ccccc2C(=O)NC1c1cc(Cl)c2c(c1)OCCO2 +CCOc1cc(Cl)ccc1NC(=O)Cc1ccc[nH]1 +C=CCc1cc(C2NC(=O)c3ccccc3N2C)cc(OC)c1O +Cn1cccc1C(=O)N1CCc2c(sc3ncnc(N)c23)C1 +CC(C)n1cnnc1SCC(=O)c1ccc2ccccc2c1 +CCOC(=O)c1cnc(NC(=O)OC(C)(C)C)o1 +CSc1ccc(CN(C)C(=O)c2cn(CC(=O)N(C)C)nn2)cc1 +CC(CCc1ccccc1)NC(=O)c1ccc(N2CCCC2=O)cc1 +C=CCNC(=O)N(Cc1cccs1)Cc1cccn1C +O=C(c1nc(CS(=O)(=O)c2ccccc2)no1)N1CCCCCC1 +COc1ccc2c(CC(=O)NCC3(C)CCCC3)cc(=O)oc2c1 +Fc1cccc(Cn2cnc3cc(F)c(F)cc32)c1 +C1CCc2nnc(C3CCCN3c3nc(C4CC4)no3)n2CC1 +COC(=O)c1cnn(-c2ccc(C(C)(C)C)cc2)c1N +CCc1nnc(NC(=O)c2ccc(CSc3ncn[nH]3)cc2)s1 +CN(C)C(=O)CN(C)S(=O)(=O)c1ccc(F)cc1 +Cn1cc(NC(=O)Nc2ccc3c(c2)OCCO3)c2ccccc21 +COc1nc(C)cc(C)c1CNC(=O)NCc1ncc(C(C)(C)C)o1 +NC(=O)c1cccc(NC(=O)c2cccc(C(F)(F)F)c2)c1 +O=C(Nc1ccccc1-c1ccncc1)c1ccnc(OC2CCC2)c1 +COC(=O)c1ccc(COc2cc(C)sc2C(=O)OC)cc1F +CCN(C(=O)c1cccc(-n2cnnn2)c1)C(C)c1ccc(F)cc1 +O=C(NC1CCCc2nc(-c3ccncc3)ncc21)c1cccc(F)c1 +O=C(Nc1cccc(-n2cnnn2)c1)C1CC(=O)N(C2CCCC2)C1 +CNC(=O)C1CC(=O)N(c2ccc(OCC(=O)N3CCCC3)cc2)C1 +O=S(=O)(Nc1ccc(Cn2cncn2)cc1)c1cccs1 +Cc1ccccc1NC(=O)Cn1c(C)nc(C)c(C)c1=O +CCCC(=O)NC1CCCN(C(=O)C(C(C)C)N2CCCC2=O)C1 +Cc1cc(C(=O)NC(C)c2ccncc2)c2c(C)nn(C)c2n1 +Cc1cc(CNS(=O)(=O)c2c(C)nn(C)c2C)c(C)o1 +CCc1ccc(S(=O)(=O)NC(C#N)c2cccs2)cc1 +Cc1noc(C)c1CN1CC2CC(C(=O)N3CCOCC3)C(C1)O2 +CC(NC(=O)c1cnn2c1CCCC2)c1cn2ncsc2n1 +O=C(NCCc1cccc(OC(F)(F)F)c1)c1ccns1 +Cc1cc(C(=O)CSc2nnc(C3CC3)n2C)c(C)s1 +CC(=O)c1c[nH]c(C(=O)NCc2ccc(-c3ccccc3)o2)c1 +Cc1nnnn1-c1ccccc1C(=O)NC1CCCC1 +CN(CC1CC1)C(=O)c1nn(C)cc1Br +Cc1cc(C)n(CCNC(=O)c2cc3ccc(F)cc3n2C)n1 +CCNS(=O)(=O)C1CCN(Cc2ccc(Cl)c(F)c2)C1 +CCN(CCO)C(=O)C1CC1c1ccc(F)cc1 +CCCCS(=O)(=O)N1CCN(c2nc3ccccc3s2)CC1 +CCc1nc(CC)n(CC(=O)N2CCC3(CC2)OCCO3)n1 +COc1cc(OC)cc(-c2nc3cc(C)cnc3o2)c1 +CCCNc1nc2c(C(=O)OC)cc(OC)c(OC)c2s1 +OCC#Cc1ccc(Cn2cc(Cl)cn2)c(F)c1 +Brc1ccccc1-n1cc(NCc2cc[nH]n2)cn1 +Cc1cc(C(=O)N2CCC(C(=O)N(C)C)CC2)n[nH]1 +COCc1nc(C)c(C(=O)OCc2cc(C)oc2C)s1 +O=C1NCCN(Cc2ccn(Cc3ccccc3)c2)C1c1ccccc1 +Cc1cc(CCCC(=O)Nc2nnc(C(F)F)s2)c(C)s1 +COc1ccc(OC)c(CC(=O)Nc2cc(Cl)ccc2O)c1 +COC(=O)c1cnc2nc(C)ccc2c1Nc1cccc(F)c1 +N#Cc1ccc(NCC2CCOC2)c(C(F)(F)F)c1 +Clc1cccc2c1C(CSc1ncccn1)NCC2 +COc1cc(Cl)c2c(c1OC)CNCC2(C)C +Cc1ccc(NC(=O)Nc2ccc3nnc(C)n3c2)c(C)c1 +Cc1cc(O)c(-c2cc(C(=O)OC(C)C)n(CCO)n2)cc1Cl +O=C(NCCC1=CCCCC1)C1CCN(C(=O)C2CC2)CC1 +N#Cc1ccccc1OCC(=O)NCCOc1ccc(Cl)cc1 +COc1ccc(NS(=O)(=O)c2ccccc2)cc1OC +CS(=O)(=O)N1CC2CCCC(O)(c3cccnc3)C2C1 +Cc1cc(C)cc(N(C)C(=O)C(C)NS(C)(=O)=O)c1 +CCCCCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CCC +CCOC(=O)C1CCN(c2c(N3CCCC3)c(=O)c2=O)CC1 +Cc1cccc(OCCC(=O)Nc2ccc(C(=O)NC3CC3)cc2)c1 +CN(CC1CCCC1)C(=O)c1c[nH]nc1-c1ccc2c(c1)OCCO2 +COC(=O)c1cc(OC)ccc1OCC(=O)N1CCOCC1 +CN1CCn2c(cnc2C(=O)Nc2cccc(F)c2)C1 +COc1ccc(Cl)cc1NC(=O)Cn1nc2c(cc1=O)CCCC2 +O=C(Nc1cccc(-n2cnnn2)c1)c1cc(-c2ccccn2)no1 +CCCn1c(C)nnc1SCc1ncoc1C +CCc1nc2nc(C)c(C(=O)Nc3ccccc3Cl)cn2n1 +NC(=O)c1cc2c(cc1N1CCCC1)NC(=O)CC2c1ccccn1 +Cc1c(C(=O)NCC2CCC(C)(C)CC2)cnn1C +CC(C)N1C(=O)C(O)(c2c[nH]c3ccccc23)c2ccccc21 +COc1cccc(CC(=O)Nc2ccc(C)cc2F)c1 +CN(CCNC(=O)c1cn(C)c2ccccc12)S(C)(=O)=O +COc1nc(N)nc2sc(C(=O)NCCCC3CCCC3)cc12 +Cc1cc(C(=O)N(C)Cc2cnc(N)nc2)c2ccc(F)cc2n1 +CCC(OC1CCCCC1)C(=O)Nc1cccc(NC(C)=O)c1C +CCOC(=O)c1c(C)oc2ncn(Cc3sc(C)nc3C)c(=O)c12 +CN(C)C(=O)CSc1nc(N)c2c3c(sc2n1)CCCC3 +CN(CCc1ccccn1)C(=O)c1ccccc1S(C)(=O)=O +CCOC(=O)C1C(=O)N=C(N2CCCCC2)NC1c1ccc(C)cc1 +CCC(=O)Nc1ccc(C)c(NC(=O)N2CCOC(C)C2)c1 +Cc1ccc(CC(=O)NCCCNS(C)(=O)=O)s1 +Cc1csc(CCCNC(=O)N2CC(=O)NC3CCCCC32)n1 +CCCn1nc(C(=O)N2CCCC2c2ccc(F)cc2)ccc1=O +O=C(NCCc1ccco1)c1noc2c1CCc1sccc1-2 +Cc1ccc(-c2cc(C(=O)Nc3cccc4c3OCCO4)on2)cc1 +CCCCCCC(C(C)O)n1cnc2c(N)ncnc21 +COc1ccc2[nH]c(=O)c(CN(C(=O)c3ccco3)C(C)C)cc2c1 +CC(O)CN1CCN(C(=O)CCC2CCCO2)CC1 +Cc1ccc(-c2cn(CC(=O)Nc3ccccc3)c(=O)o2)cc1 +CCc1cnc(C(C)NC(=O)c2cn(C)nc2C(C)(C)C)s1 +CC(C)(C)NC(=O)CNC(=O)NCCc1cccs1 +N#CCc1c(Br)cc(F)c(F)c1F +CCCNC(=O)CNc1ccc(-n2nc(C)cc2C)c(F)c1 +COc1ccccc1CCC(=O)N1CC(C(N)=O)CCC1C +CC(C)CNC(=O)Nc1ccc(N2CCOC2=O)cc1 +Cc1nnc(NC(=O)CCS(=O)(=O)c2ccccc2)s1 +O=C(NCCCOc1ccc(Cl)cc1Cl)C1CCCO1 +Cc1nn(C)c2ncc(NC(=O)c3ccc4ncsc4c3)cc12 +Cc1cc(C2CCCN(C(=O)C3Cc4ccccc4S3)C2)n[nH]1 +COCCc1noc(C2CCC(=O)N(C3CCCC3)C2)n1 +Cc1cc(CN(C)C(=O)NCc2ccnc(-n3cccn3)c2)no1 +COC(=O)CCC(=O)Nc1ccc2c(c1)OC(F)(F)O2 +CN(Cc1nc2ccccc2[nH]1)C(=O)c1cnns1 +Cc1cc(NC(=O)c2ccncc2)n(-c2ccccc2C(F)(F)F)n1 +COC(=O)C1(NC(=O)CC(NC(C)=O)c2ccc(C)cc2)CCCC1 +CN(C)C(=O)Cc1ccc(NC(=O)c2cc(-c3ccco3)on2)cc1 +COc1nc2c(cc1C(=O)NCc1ccccn1)CCC2 +COc1ccc2[nH]cc(C(=O)NCc3ccccc3)c2n1 +CC(C)C(C#N)NC(=O)c1cccc(OCc2cccnc2)c1 +C#CCN1CCN(CC(=O)N(C)C(C)c2cc3ccccc3o2)CC1 +CS(=O)(=O)c1ccc2nc(NC(=O)C3CC=CC3)sc2c1 +CCc1cccc(CC)c1NC(=O)COC(=O)c1cc(C)oc1C +Cc1cc2cccc(N)c2c(=O)n1Cc1ccccc1 +Cc1ccccc1CN(C)C(=O)NCc1cc(=O)[nH]c2ccccc12 +CC(=O)Nc1cc(C(=O)NCCCO)ccc1C +Cc1cc(NC(=O)Cn2nnc3ccccc32)no1 +COc1ccc(-n2nnc(C(=O)N3CCCCC3)n2)cc1 +CNc1ccccc1C(=O)OCC(=O)N1CCc2ccccc2C1 +CCS(=O)(=O)N1CCN(CC(=O)N2CCc3ccccc32)CC1 +O=C(Nc1ccccc1C(=O)N1CCCCC1)C1CC=CCC1 +CC(C)Oc1ccc(CNC(=O)c2cc(C3CC3)[nH]n2)cn1 +CC1CCC(C(=O)Nc2ccccc2C(=O)C(C)C)O1 +CN(CCO)C(=O)Cc1csc(-c2cccc(N)c2)n1 +COCCOc1ccc(C#N)cc1NC(=O)c1ccco1 +Cc1cc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)no1 +CCn1ccc(=O)c(NC(=O)c2cc(C)n(CC)c2C)c1 +CCOCc1ccc(CNC(=O)NCC2CC2)cc1 +CC(C(=O)NCc1cc(Br)ccc1F)n1cncn1 +CCN(CC(=O)N1CCC(C)CC1)S(=O)(=O)c1ccc(C)cc1 +COCCNC(=O)Nc1ccc(Oc2ccccc2OC)c(F)c1 +O=S(=O)(CCNS(=O)(=O)c1ccccc1)c1ccc(F)cc1 +Cc1cccc(C)c1NC(=O)Cc1cccc(N)c1 +O=C(Nc1cnc(-c2ccccc2)nc1)C1CC=CCC1 +NC(=O)COc1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1 +COCCNC(=O)CN(C)c1ccc(F)cc1CO +Cc1csc(C2CCCCN2C(=O)C2Cc3cc(F)ccc3O2)n1 +Cc1nc(-c2cccnc2)sc1C(=O)Nc1ccccc1 +COC(=O)c1ccc(C2NC(=O)c3ccccc3N2C)cc1 +CC(C)C1C(=O)NCCN1Cc1csc(C2CCCCC2)n1 +CCOC(=O)c1[nH]c(C)c(C(=O)NC(C)C)c1C +Cc1ccc(CNS(=O)(=O)c2ccccc2F)cn1 +CN(C)c1ccnc(NC(=O)c2ccc(N(C)C)nc2)c1 +O=C(NC(c1ccccc1)n1nnc2ccccc21)c1cccnc1 +COCCc1ccc(OCC(=O)NC2CCC(C)CC2)cc1 +CC(NC(=O)C1CC=CCC1)c1ccc2c(c1)NC(=O)CO2 +c1cc2c(cc1OCc1nc3c(s1)CCCN3)OCO2 +CCOC(=O)c1c(NC(=O)c2ccccc2F)sc(C)c1C +Cc1cc(C)n2nc(SCC(=O)N(C)CC3CCCCC3)nc2n1 +COCCOc1cc(-c2nc(-c3ccccn3)no2)ccn1 +O=C(NC1CCN(C(=O)c2ccoc2)CC1)c1cccc2ccccc12 +Cc1cc(Br)cc(S(=O)(=O)NCc2ccco2)c1 +Cc1cc(NC(=O)CCN2CCc3ccccc32)no1 +COC(=O)C1CC1C(=O)Nc1cccc(-c2ncc[nH]2)c1 +CN(CCc1ccc(F)cc1)C(=O)NCC(F)(F)F +COC(C)(C(=O)NCC(=O)NCc1ccccc1)c1ccccc1 +CCN(CC)C(=O)CNc1cccc(C(=O)N2CCOCC2)c1C +Cc1ccc(NC(=O)Nc2ccc(C(N)=O)cc2)c(C)c1 +Cc1cc(=O)c(C(=O)NC(C)C)nn1-c1ccccc1F +Cc1csc(N2CCN(C(=O)Nc3ccccc3N(C)C)CC2)n1 +CCCn1cc(CCNC(=O)c2ccc(F)cc2F)c2cccnc21 +Cn1c(=O)n(CCC(=O)Nc2cn[nH]c2)c2ccccc21 +CC(C)NC(=O)C1CC(=O)N(c2cccc3ccccc23)C1 +Cc1csc(CCNC(=O)Nc2cccnc2-n2cccn2)n1 +CCC(CC)NC(=O)CSc1nnnn1-c1ccc(C)cc1C +Nc1cccc(NC(=O)CCCN2CCOC2=O)c1 +CCc1nc(-c2ccc(C(=O)Nc3cc(OC)ccn3)cc2)n[nH]1 +COc1ccc(C2c3c(C)n[nH]c3C(=O)N2C)cc1OC +COC(=O)N1CCC(NC(=O)CCn2c(C)csc2=O)CC1 +Cc1ccc(-c2noc(CN(C(=O)c3ccco3)C(C)C)n2)cc1 +Cc1ccc(CNC(=O)c2cc[nH]n2)c(OCC2CCOC2)c1 +COCCNC(=O)CCNC(=O)c1cccc(Cl)c1Cl +Cc1ccc(C)c(OCCc2ncc(C#N)s2)c1 +C=CCn1cc(CN2CCN(CC(=O)OC)C(=O)C2C)c(C)n1 +CC(NC(=O)c1c(F)c(F)c(F)c(F)c1F)C1CCCO1 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+CN(CC(=O)c1ccco1)C1CCN(C(=O)OC(C)(C)C)CC1 +COC(C(=O)NC1CCN(c2c(F)cccc2F)C1)c1ccccc1 +Cc1ccc(Cl)c(S(=O)(=O)N(C)CC(C)O)c1 +COCc1ccccc1C(=O)NCCc1nc2ccccc2s1 +O=C(Cc1ccc(F)cc1F)N1CCOc2cc(F)ccc21 +CCCCOc1ccc(-c2ccc(C(N)=O)c(N)n2)cc1 +CN(Cc1ccc(F)cc1)C(=O)CNc1ccc(F)c(F)c1F +C=CCN(CC=C)C(=O)C(C)N1CCc2cc(F)ccc2C1 +c1ccc(CN2CCOC3C(Oc4cccnc4)CCC32)nc1 +Cc1nsc(NC(=O)N2CCc3nc[nH]c3C2c2ccccn2)n1 +COC(=O)CN(C)C(=O)c1nccc2cc(N)ccc12 +Cc1ccccc1OCCCn1cnc2ccccc2c1=O +COc1cc(C(C#N)c2ccc(N)cn2)cc(OC)c1OC +CCOC(=O)N1CCN(Cc2cc(-c3ccco3)on2)CC1 +Nc1nonc1-c1nnnn1CC(=O)Nc1cccc2ccccc12 +Cc1cc(N2CCC(Cn3cc(C4CCCC4)nn3)CC2)nc(N)n1 +Cn1cc(NC(=O)NCc2ccc(Oc3ccc(F)cc3)cc2)cn1 +N#Cc1cccc(C(=O)NCCn2ccnc2-c2ncccn2)c1 +Cc1noc(C)c1CC(C)NC(=O)Cc1ccc(F)c(F)c1 +CCn1cc(C(=O)Nc2ccccc2-n2ccnc2)cn1 +CC(=O)Nc1ccc2c(c1)C(c1ccncc1C)NCC2 +CN(CC(=O)NC(C)(C)C)C(=O)Cc1cccs1 +CCC1(CC)Nc2cc(Cl)ccc2N(CCO)C1=O +O=C(NCc1nnc2n1-c1ccccc1CC2)c1ccccc1 +CC(=O)Nc1ccc(C#CCNC(=O)c2ccc(=O)oc2)cc1 +Cc1ccc(-n2nnc(C#N)c2C2CC2)cc1Cl +CCc1cccc(NC(=O)Cn2c(=O)c3nncn3c3ccccc32)c1 +CCc1nc(NCCCn2cccn2)c2c(n1)c(C)nn2C +CCCn1nc(-c2ccc(C)o2)nc1C1CCc2nn(C)c(=O)n2C1 +CC(C)N(C(=O)COc1cccc(C(=O)N(C)C)c1)c1ccccc1 +COCCC(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +COC(=O)C1CCCCCC1NC(=O)NC1CCC(O)CC1 +CC(C)CS(=O)(=O)Nc1ccc2c(c1)OCC(C)(C)C(=O)N2 +Cc1cc(C)cc(C(=O)OCC(=O)Nc2ccc(C(N)=O)cc2)c1 +CCCNC(=O)Cc1csc(NC(=O)Nc2ccc(C)cc2)n1 +CC(=O)Nc1ccc(CNC(=O)c2ccccc2O)cc1 +Cc1nc(C)c(C(=O)NCCn2nc3ccccn3c2=O)s1 +C#CCNC(=O)CCC(=O)N1CCOc2ccccc21 +COc1cccc2c1CCNC2CNC(=O)OC(C)(C)C +CCN(C(=O)COC(=O)c1ccc(C)nc1)c1cccc(C)c1 +CN(Cc1cnc(N2CCCC2)nc1)Cc1cnn(-c2ccccc2)c1 +CCN(CCc1ccccc1)Cc1nc2ccsc2c(=O)[nH]1 +CNC(=O)c1cccc(OC(=O)C2CCOCC2)c1 +CCc1nc2c(N)cccc2n1CC(=O)NC1CCCC1 +CN(Cc1cnn(C)c1)C(=O)c1cccc2[nH]ccc12 +Nc1ccc(-c2nnc(COc3ccc(Cl)cc3)o2)cc1 +Cn1cnnc1-c1ccc(NC(=O)c2cccc3c2OCCO3)cc1 +O=C(NCCC(O)C1CC1)c1c(F)cccc1Cl +Cc1ccc(OCCNC(=O)NC2CCN(C(=O)C(C)C)CC2)cc1 +CCOC(=O)c1ccc(N2CCN(C(=O)c3ccsc3)CC2)nc1 +COc1cc(CNC(=O)NCc2ccc(C)nc2)c2ccccc2n1 +Cc1cccc(Cn2c(N(C)C)nc3c2c(=O)n(C)c(=O)n3C)c1 +O=C(CC(F)(F)F)Nc1cccc(CN2CCCCC2=O)c1 +Cc1cnn(CC(C)NCc2c(C)n(C)n(-c3ccccc3)c2=O)c1 +CC(=O)N(CC(C)C)c1nc(C)c(C(=O)NCc2ccco2)s1 +CCN(CC)c1nc(-c2ccccc2)ncc1C(=O)NCC1CC1 +CC(=O)Nc1ccc(NC(=O)C(C)Oc2cccc(C)c2)cc1 +CC(=O)Nc1ccc(C(=O)Nc2nnc(-c3ccsc3)o2)cc1 +CCC1(CO)CCCN(C(=O)c2ncoc2C2CC2)C1 +Cc1cccc(OCc2nc(C)c(CCO)c(=O)[nH]2)c1C +CC1CC1CNC(=O)Cn1nnc(-c2ccccc2)n1 +COc1cc(CSc2nc(N)cc(N)n2)cc(OC)c1OC +CCc1nnc2n1CCN(CCOc1ccc3ccccc3c1)C2 +C=CCSc1nnc(-c2c[nH]c3ccccc23)o1 +O=C(NCc1ccccc1)c1ccc(-c2ccc(F)cc2)[nH]c1=O +O=C(NCc1ccco1)C1CC2CN(CCO)CC1O2 +Cc1ccccc1-c1noc(COC(=O)c2cccnc2N(C)C)n1 +Cc1nc2ccc(NC(=O)NCc3ccccc3)cc2o1 +COC(=O)CC(C)C(=O)NC1(c2ccc(F)cc2F)CCOCC1 +COc1ccc(NC(=O)c2ccc(OC)c(Cl)c2)c(N)c1 +Nc1nc(C2CCCO2)ncc1C(=O)Nc1ccccc1F +COC(=O)c1ccc2c(c1)nc(CO)n2C(C)(C)CO +N#Cc1ccc(NC(=O)NCc2ccccc2CO)cc1 +O=C(NC(CC1CCCCC1)c1ccccc1)C1COCCO1 +CC(C)COc1ccc(NC(=O)C(C)C)c(N)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cc2ccccc2oc1=O +Nc1cccc2c(C(=O)Nc3ccccc3)nccc12 +c1csc(-c2noc(CCN3CCOCC3)n2)c1 +CC(C)C(=O)c1ccccc1NC(=O)CCC1CCOCC1 +N#Cc1ccc(NC(=O)N2CCCC2c2ccsc2)cc1 +COc1cc(CCNC(=O)NCC(C)(C)c2ccncc2)ccc1O +COCc1ccccc1CNC(=O)N1CCN(S(C)(=O)=O)CC1 +COc1cc(CCNC(=O)C(NC(C)=O)C(C)C)ccc1C +COc1ccc(C)cc1Cn1nnc(-c2ccccc2)n1 +COc1cccc(NC(=O)Cn2nnc3ccccc32)c1 +O=C(c1cncn1-c1ccccc1)N1CCOCC1 +O=C(Cn1ccc2c(cnc3ccnn32)c1=O)Nc1ccccn1 +Cn1ccnc1SCC(=O)Nc1ccccc1C#N +CCn1cc(S(=O)(=O)c2ccccc2)c(=O)c2cc(C)ccc21 +CC(Cc1ccccc1)C(=O)N1CCOCC1C1CC1 +Cn1c(=O)n(CC(=O)N2CCOc3ccc(F)cc32)c2ccccc21 +CN(Cc1cccc(OC(F)(F)F)c1)C(=O)C1CC2CCC1O2 +CC(C)Nc1ccc(S(=O)(=O)N(C)C)cc1N +CCN(CC)c1ccc(C(=O)CCN2CCOCC2)cc1C +C#Cc1cccc(N(CCOC)Cc2cccs2)c1 +NC(=O)C(Sc1ncc(-c2ccc(F)cc2)o1)c1ccccc1 +COCCNC(=O)C(C)S(=O)(=O)c1nc(C)cs1 +COc1cccc2c1CCNC2c1cccc(C)n1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)NC1CCCc2occc21 +CCOc1ccccc1Cn1cnc(C(=O)OC)n1 +CC(NC(=O)NCc1cccnc1)c1nc(-c2ccc(F)cc2)no1 +COc1ccccc1C(N)C(=O)NCC1CCCO1 +Cc1nn(C)c(C)c1CCc1nc(-c2cc3ccccc3o2)no1 +COC(=O)c1cccc(CCNC(=O)c2c(F)cc(C#N)cc2F)c1 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+CCc1cc(NC(CC)c2ccccn2)nc(N2CCOCC2)n1 +CCC(NC(=O)c1cc(C)nc2ccc(C)cc12)c1ccnn1C +Cc1cccc(NC(=O)C2CN(C(=O)c3c[nH]c4ccccc34)C2)n1 +COc1ccc(CC(=O)Nc2ccc(Cn3cccn3)cc2)cc1F +O=C(Cc1ccc(F)cc1F)Nc1ccccc1N1CCOC1=O +CCC(C(=O)N(Cc1ccccc1)C1CC1)c1c(C)noc1C +Cc1cc(F)ccc1NCc1cnn(-c2ccccc2)c1 +CCc1[nH]ncc1C(=O)N1CCOC(c2nc(C)n[nH]2)C1 +Cc1ccc2oc(=O)c3cnn(CC(=O)Nc4ncccc4C)c3c2c1 +CC(C)N1CC(C(=O)Nc2ccn(-c3ncccc3Cl)n2)CC1=O +CC(NC(=O)c1ccncc1)c1ccc(OCC(=O)NC2CC2)cc1 +CC(=O)Nc1ccc(NC(=O)CC2CC3CCC2C3)cc1 +NC(=O)c1ccccc1NC(=O)c1ccc(=O)n(-c2ccccc2)n1 +Cc1ccc(C)c2[nH]c(=O)c(CCNC(=O)C3CCCC3)cc12 +O=C(OCc1nnc(-c2ccccc2)o1)c1ccccc1Cl +COCc1ccc(C(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)cc1 +CC(C)CCn1c(SC(C)C(=O)N(C)C)nc2ccccc21 +Cc1nnc(SCC(=O)N(c2ccccc2)C2CCCCC2)n1C +CNC(=O)Cn1cnc2c(nnn2-c2ccccc2)c1=O +Cc1ccc(-n2cnnn2)cc1NC(=O)C1COc2ccccc2C1 +CC(C)COC(=O)Nc1ccc2nc(N3CCOCC3)sc2c1 +CCCn1nnc(CO)c1COc1ccc(C)cc1 +CCNc1nc(C2CCCO2)nc(OCC(C)C)c1N +CC(C)COC(=O)N1CCCN(C(=O)Cc2ccc[nH]2)CC1 +CCC(C)OC(C)C(=O)Nc1cc(N)ccc1C +O=S(=O)(CCc1nc2ccccc2s1)c1ccc(Cl)cc1 +CCC(CNC(=O)Cc1csc(C)n1)c1ccccc1 +CCC(CC)C(=O)N(C)Cc1cc(=O)[nH]c2ccccc12 +Cc1nc(C)c(C(=O)NC(c2ccccc2)c2ccccc2)s1 +O=C(NC1CC1)C1CCN(C(=O)C2CCCCC2C(F)(F)F)CC1 +CS(=O)(=O)N1CCN(C2CCC(c3ccccc3)CC2)CC1 +CC(Oc1ccc(-c2nnco2)cc1)C(=O)N(C)c1ccccc1 +COc1ccc(CC(=O)NCC(O)c2ccccc2Cl)cc1OC +CCn1cc(CN(C)C(=O)Cc2c(C)[nH]c3c(C)ccc(C)c23)cn1 +CCc1ccc(OCCCn2nnc(CO)c2C)cc1 +CC(C)c1ccc2c(c1N)CS(=O)(=O)N2C(C)C +O=C(NCc1cscn1)N1CCN(C(=O)C2CCCO2)CC1 +CN(C)C(=O)N1CCCn2nc(CNc3nccs3)cc2C1 +Cc1ccc2c(CSc3nnc(C)c(=O)n3N)cc(=O)oc2c1C +CC(=O)c1ccc(N2CCN(C(=O)c3ccccc3)CC2)c(F)c1 +COc1ccccc1NC(=O)N1CCCC1c1c(C)noc1C +O=C(NCc1ccc2c(c1)OCO2)C1CC(=O)N(Cc2ccco2)C1 +Cc1ccc(-c2cccc(-c3ccn(Cc4cc(C)on4)n3)c2)cn1 +O=C(COC(=O)Cc1ccsc1)NCc1ccc2c(c1)OCO2 +O=C(Nc1cccc2cccnc12)c1ccn(C2CCCC2)n1 +CN(C(=O)NC1CCCCNC1=O)C(C1CC1)C1CC1 +N#Cc1cccc(NC(=O)CCSc2nnnn2C2CC2)c1 +CC(C)NC(=O)C(C)N1CCN(c2cc(C(F)(F)F)ccn2)CC1 +N#CC(C(=O)C1CC=CC1)c1nc(-c2ccccc2)cs1 +c1ccc2c3c(ccc2c1)C(c1cnccn1)NCC3 +Cc1nc(C)c(CC(=O)NCCOc2cccc(Cl)c2)c(=O)[nH]1 +Cc1cc(C)n2cc(CSc3nc4ccccc4[nH]3)nc2n1 +CNC(=O)c1ccc(Cl)cc1NCCOc1ccc(C#N)cc1 +Cc1ccsc1CNC(=O)C1(c2ccccc2)CCOCC1 +Cc1ccc(OC(=O)CCn2ccccc2=O)c(Br)c1 +O=C(CN1CCN(c2ccccc2)C1=O)Nc1ccc(F)cc1 +CCc1nc(CCNC(=O)NC2CCCC3OCCC23)sc1C +OCc1csc(CCOc2ccc(Cl)cc2)n1 +CNC(=O)c1ccc(Cl)c(NC(=O)c2cc(C)sc2C)c1 +CCN1CCc2nc3sc(C(=O)OC)c(N)c3cc2C1 +CCc1cc2c(=O)n(CC(=O)NC3CC3)cnc2s1 +Cc1ccc(OCC(=O)NCc2ccccc2)c(C)c1 +O=C(NCc1cn2c(n1)SCC2)c1cc2sccc2[nH]1 +CC(C)N(CC(N)=O)C(=O)c1cc(N)cn1C(C)C +CNC(=O)c1c(C)cccc1NCc1nccn1C(F)F +N#CC(CCC(=O)N1CCCCC1)c1ccccc1F +COc1ccc(CN(Cc2ccccc2F)CC2CCCO2)cc1O +O=C(Cn1nnc2ccccc21)NCCCn1ccnc1 +CC(O)CNC(=O)C(Cc1ccccc1)NC(=O)c1cccs1 +O=C(CC1(O)C(=O)Nc2ccc(Br)cc21)c1ccccn1 +COc1ccc(C)cc1CCNCc1ccc(-n2cccn2)cc1 +CCCc1nc(C)c(CNC(=O)C2CCCN(C(=O)CC)C2)s1 +Cc1cccc(C)c1OC(C)C(=O)N1CCC(=O)CC1 +O=C(Cc1ccccc1)Nc1cc(-c2ccncc2)n[nH]1 +COCCCN(C)C(=O)Nc1cccc(Cl)c1N(C)C +CC(C)N(C)S(=O)(=O)c1cccc(C(=O)N(C)C2(C#N)CCC2)c1 +COc1ccc(C(=O)C(C)OC(=O)c2ccc(NC(C)=O)s2)cc1 +Cc1c(C(=O)Nc2nncs2)cnn1-c1ccncc1 +COc1ccccc1OC(=O)Cc1cc2ccccc2[nH]c1=O +Cc1ccc(C)c2sc(OC3CCN(S(C)(=O)=O)CC3)nc12 +Cc1nc(CN(CCCO)Cc2ccc(Cl)c(Cl)c2)cs1 +CCOC(=O)c1cccc2[nH]c(=O)n(C3CCCC3)c12 +COc1ccc(C(=O)Nc2cccc3ccc(C)nc23)nn1 +Cc1cc(COC(=O)c2ccc(S(C)=O)cc2)c2ccccc2n1 +CCOC(C)c1noc(COc2cccc(-c3nnco3)c2)n1 +CCCCn1c(=O)[nH]c(=O)c2[nH]c(NCCCO)nc21 +NC(=O)C(c1ccccc1)N1CCN(c2ccc(Cl)cc2)CC1 +CN(Cc1ccco1)C(=O)CN1CCN(C(=O)c2ccco2)CC1 +O=C(Nc1ccc(OCC2CC2)cc1)c1ccc2ccnn2c1 +CCCCNC(=O)c1nnc(C(=O)Nc2ccc(C)cc2)s1 +Cc1cccc(SCC(=O)N(C)CC(=O)N2CCOCC2)c1 +Nc1nc(-c2cccnc2)nc(N2CCCCC2)n1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCC1CCCCC1 +CC(=O)N1CCc2cc(NC(=O)c3cnc4[nH]nc(C)c4c3)ccc21 +Cc1ccc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1C +Cc1ccc(CN(C)C(=O)C2CCN(c3cnccn3)CC2)s1 +Cc1ccc(-c2ccc(C(=O)NC3CCCC3C(N)=O)s2)o1 +CC(=O)c1sc(-c2ccncc2)nc1-c1ccccc1 +CCOC(=O)N1CCN(c2ncnc3sccc23)CC1 +CCCn1c(NC(=O)c2cccnc2N2CCCC2)nc2ccccc21 +CC(C)(O)CN1CCN(C(=O)C2CC2c2ccccc2)CC1 +Cc1csc(NC(=O)Nc2cnn(CC3CCCO3)c2)n1 +Cc1ccccc1CN(C)C(=O)C1COc2ccccc2O1 +CC(C)N(C)C(=O)Nc1cc(C(N)=O)ccc1N(C)C +CC(C)(C)C(=O)Nc1ccc(C(=O)Nc2ccccc2O)cc1 +CCCCc1nnc(NC(=O)c2c[nH]nc2-c2ccc(F)cc2)s1 +CN(C(=O)c1ccccn1)c1cccc2ncccc12 +CC1CC(C)CN(C(=O)c2coc(NC(=O)c3ccco3)n2)C1 +CCC(=O)Nc1ccc(O)c(C(=O)N(CC)CC)c1 +COc1cc(CNc2ccc(C)c(NC(C)=O)c2)cc2c1OCCO2 +CC(NC(=O)c1cccc(C#N)c1)c1ccc(S(N)(=O)=O)cc1 +CC(=O)NCC(=O)Nc1ccc(Oc2ccc(Cl)cc2)nc1 +C#Cc1cccc(N(Cc2nnc(-c3cc(C)oc3C)o2)C(C)C)c1 +Cn1ccc2c(cc(C(=O)N3CCCCC3)n2C)c1=O +C=CCN(CC=C)C(=O)C(C)NC(=O)c1ccncc1 +CCOC(=O)c1sc(=NC(=O)c2n[nH]c3c2CCC3)[nH]c1C +CCNC(=O)N1CCN(CCS(=O)(=O)c2ccccc2)CC1 +Cn1cccc(C(=O)NCc2cc(-c3ccco3)on2)c1=O +Cc1ccc(OCc2nc(C(=O)OC(C)C(N)=O)cs2)cc1 +CCc1ccc(S(=O)(=O)N2CCN(C3CC3)CC2)cc1 +COc1cc(Cl)c(C)cc1-n1ncc2c(=O)[nH]cnc21 +CCC(NC(=O)N1CCC(NS(C)(=O)=O)CC1)c1cccs1 +CCCC(C)c1n[nH]c2c1CN(C(=O)c1[nH]nc3c1CCC3)CC2 +CC1(NS(=O)(=O)c2c(F)cccc2Cl)CCOC1 +COCCn1nc(C)c(CNC(=O)c2ccc(C(N)=O)cc2)c1C +COCCCn1c(SCc2n[nH]c(=O)[nH]2)n[nH]c1=O +CC(C)C(=O)c1ccccc1NC(=O)c1cc2c(s1)CCOC2 +CC1CCC(NC(=O)COC(=O)c2n[nH]c(=O)c3ccccc23)CC1 +Cc1ccccc1CNC(=O)CN1CCCCCC1=O +Cc1ccc2nc(-c3cccc(NC(=O)C4CCCO4)c3)[nH]c2c1 +COc1ccccc1C(=O)N1CCn2c1nc1ccccc1c2=O +CC(C)(C)c1ccc(NC(=O)COc2cccnc2N)cc1 +NC(=O)C1CCCC1NS(=O)(=O)c1cccc2ccccc12 +O=C(Nc1ccc(F)cc1)c1cnc2sc3ncccc3c(=O)n12 +COC(C)C(=O)NCc1ccc(-n2cncn2)cc1 +COc1nccc(N2CC(NC(C)=O)C(c3ccc(C)o3)C2)c1C#N +Cc1ccc(CN(C)S(=O)(=O)Cc2cccc(C#N)c2)cc1 +O=C(Nc1ccncc1)Nc1ccc(F)c(Cl)c1 +COc1cccc2cc(C(=O)Nc3sc(C)c(C)c3C(N)=O)oc12 +CC(OCC1CC1)C(=O)NC1(C)Cc2ccccc2C1 +Cc1cccc(OC(C)C(=O)NCc2cn(C)nc2C)c1 +CCN(CCc1nc2ccccc2c(=O)[nH]1)Cc1cccc(C)c1 +O=C(Nc1cccc(NC(=O)C2CC2)c1)NC1C2CCC(C2)C1CO +CNc1oc(-c2ccc(S(=O)(=O)N(C)C)o2)nc1C#N +N#Cc1ccc(C(N)c2nnc(CC3CC3)o2)cc1 +CC(c1ccc(F)cc1)N(C)C(=O)CSc1n[nH]c(=O)n1C +N#CCCNC(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O +COC(=O)C1CC(O)CN1C(=O)CCn1c(C)cc2ccccc21 +COc1cccc(C(=O)OC2CCCC(OC)C2)c1F +CCN(C(=O)c1cc2cnn(CC)c2nc1N)c1ccccc1 +O=S(=O)(NCCC(O)c1cccc2ccccc12)c1ccccc1 +CCN(CC(C)C#N)C(=O)c1cc2ccccc2o1 +Cc1ccc(C(=O)N2CCC(C)(O)C(O)C2)cc1F +CC(=O)c1ccc(NC(=O)C2CCCN(C(=O)C3CC3)C2)cc1C +O=C(CN1C(=O)CCCc2ccccc21)NCc1ccccc1 +COc1cc(C(C)=O)ccc1OC(=O)c1cnc(-c2ccccc2)nc1 +CCc1cc2c(=O)n(CC(=O)Nc3nnc(C)s3)cnc2s1 +O=S(=O)(NCCn1ccc(-c2cccs2)n1)C1CC1 +COc1ccc(CC(=O)N2CCCC(CNC(=O)C(C)(C)C)C2)cc1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)c1ccccc1OC(F)F +COC(=O)Cc1csc(NC(=O)c2ccncc2F)n1 +CC(NC(=O)Nc1ccc(Oc2cccnc2)nc1)c1ccccc1 +Cc1ccc(C(C)NC(=O)C2CCC(=O)N2)cc1F +Nc1cccc(-c2nc(Cc3cccs3)no2)c1 +Cc1cc(C(=O)Nc2cccc(N3CCCCC3=O)c2)sc1C +CC(C)c1ccc(NC(=O)c2ccccc2-n2cnnn2)cc1 +CCN(CC)C(=O)CN(C)C(=O)CSc1ccc(F)cc1 +CCOC(=O)N1CCN(C(=O)c2cc(C)nc(SC)n2)CC1 +Cc1ccc2cc3c(NC(=O)c4ccccc4)nn(C)c3nc2c1 +O=C(NC1CCOC1c1ccc(Cl)cc1)c1ccccn1 +COC(=O)c1ccc(CN(C)C(=O)c2ccc(=O)[nH]c2)cc1 +COCc1nc2n(n1)CC(NC(=O)NCC1CCC(C)(C)CC1)CC2 +Cc1cnn(C2CCCN(C(=O)CCCOc3ccccc3F)C2)c1 +CC1CCN(C(=O)Nc2noc3c2COc2ccccc2-3)CC1 +Cn1c(C(=O)NCC(F)(F)F)nc2cccnc21 +Cc1c(Cl)ccc(-c2ccc(C#N)c(=O)[nH]2)c1F +Cc1c(C(=O)OCC(=O)N2CCCC2)cnn1-c1ccc(F)cc1 +CC#CC1NCCc2cc(OC)c(O)c(Br)c21 +Cc1ccc(OCCNC(=O)c2ccc3ccccc3n2)cc1 +COc1cc(CNc2cccc(O)c2)cc(OC)c1O +CC(C)Nc1nc(CCc2ccccc2)nc2c1cnn2C +CC(=O)N1CCN(S(=O)(=O)c2c(C)c(C)c(C)c(C)c2C)CC1 +O=C1CCC(COC(=O)c2cn(-c3ccccc3)nn2)N1 +CCNC(=O)NC(C)c1cccc(OC(F)F)c1 +Cc1cc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)c(C)o1 +CCc1cc(CC(C#N)c2c(C)noc2C)ccc1OC +CCc1noc(CC)c1CNC(=O)c1cccc2c1OCCO2 +NC(=O)c1ccc(CS(=O)(=O)c2ccccc2F)cc1 +COCC(=O)N1CCC(NC(=O)c2ccc(F)cc2)CC1 +Cc1cc2nc(N)nn2cc1N1CCN(c2ccc(F)cc2)CC1 +COc1ccc2[nH]cc(C(=O)Nc3ccccn3)c(=O)c2c1 +CC(C)c1nc(Cn2c(CO)nc3ccccc32)cs1 +CC(=O)N1CCN(C(=O)c2nc(-c3cnccn3)no2)CC1 +O=C1OCCN1Cc1ccc(F)c(C(F)(F)F)c1 +Cc1ccc(C(=O)Nc2cccc(OCC(N)=O)c2)c(C)c1 +Cc1ccc(NC(=O)NCc2cc(-c3ccncc3)n(C)n2)cc1C +O=C(Cc1ccccc1)Nc1snc2c1CCC2 +CCN(Cc1ccccn1)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +Nc1ncc(CNCCc2ccc(Cl)cc2)cn1 +CC(C)N(CC(N)=O)C(=O)c1ccc(Cl)cc1N +Cc1cnc(N2CCC3OCCN(Cc4ccncc4)C3CC2)nc1 +CCCn1c(=O)c2sccc2n2c(=O)n(C)nc12 +CCCCNC(=O)c1ccc(-c2cc(F)ccc2F)nc1N +CNC(=O)C(C)Nc1ccc(N)cc1C(=O)OC +Cc1ccc(-c2cc(=O)[nH]c(Cc3ccccc3F)n2)cc1N +CC(=O)NCc1ccc(C(=O)N(C)C(C)c2ccccc2Cl)cc1 +Cc1ccc(Br)cc1CCCn1cc(N)cn1 +FC(F)(F)c1ccc(Cn2cc(Cl)cn2)cc1 +CC(C)N(CCC#N)C(=O)c1csc2ccccc12 +CC1CC1C(=O)NCc1ccc(S(=O)(=O)N2CCOCC2)s1 +CCN(CC1CC1)C(=O)Nc1ccnn1C1CCCCC1 +CC(C)n1nnc(CC(=O)NCC2(c3cccc(F)c3)CCCC2)n1 +COCCNc1ncnc(Oc2ccccc2)c1N +CCc1c(C(=O)Nc2ccncc2)cnn1Cc1ccccc1 +CC(=O)NC(C)C(=O)Nc1cc(Cl)ccc1C +CCn1ccc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)n1 +CCC(C)(C)NC(=O)C1CCN(c2ccc(F)c(F)c2)C1=O +CN(C1CCCCC1)S(=O)(=O)NCc1ncn(C)n1 +CCn1ncc(CN(C)S(=O)(=O)c2c(C)nn(C)c2C)c1C +CC(=O)c1ccc(NC(=O)c2ccccn2)cc1C +CCCNC(=O)C1CCCN(c2nnc(N3CCCC3=O)s2)C1 +Cc1nc(C(=O)NCC(=O)N2CCCCC2)cs1 +CC(NC(=O)CCc1ccsc1)c1ccc(S(N)(=O)=O)cc1 +O=C(COc1ccc2c(c1)OCO2)Nc1ccc(Cl)cc1 +O=C(Nc1ccc(C(=O)Nc2ccc(F)cc2F)cc1)NC1CC1 +COc1ccc(SCCC(=O)Nc2ccc(N(C)C)nc2)cc1 +O=C(NCCCn1cccn1)NCC1(c2ccc(F)cc2F)CC1 +C#CCN1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 +CCn1c(=O)n(CC)c2cc(NC(=O)Nc3cccc(F)c3)ccc21 +CCC(C)NC(=O)c1cc(=O)oc2cc(OC(C)C)ccc12 +CC(=O)NC(C(=O)NC1CCCc2ccccc21)C(C)C +Cc1nc2nc(C)c3c(=O)n(-c4cccc(F)c4F)ccc3n2n1 +Cc1noc(CNC(=O)CCNS(=O)(=O)c2ccccc2)n1 +CCc1ccccc1NC(=O)c1c[nH]c(=O)n(-c2ccc(C)cc2)c1=O +Cc1ccc2c(c1)NCCN2CC(=O)Nc1nccs1 +Cn1ccc(C(=O)NCc2ccccc2OC(F)F)cc1=O +O=C(c1nc(-c2cccs2)cs1)N1CCOCC1 +O=C(NCc1cscn1)c1cc2ccc(Cl)cc2[nH]1 +COC(=O)c1cn(C2CCCCC2OC(=O)C(C)C)nn1 +CCN(Cc1ccccc1)C(=O)Cn1nnc(-c2cccs2)n1 +Cc1cc(C(=O)NCC(c2ccco2)N2CCOCC2)no1 +Cc1cc(-c2nnc(CN3CCC4(C3)OCCO4)o2)c(C)o1 +Cc1nc(-c2ccc(CCNC(=O)Nc3ccn(C)n3)s2)cs1 +CCc1nsc(N2CCC3(CC2)OCC(C)O3)n1 +O=C(COCC1CCCCO1)N1CCc2[nH]ncc2C1 +COC(=O)C(NC(=O)COc1ccccc1C)C(C)C +COc1cc(C#N)ccc1OS(=O)(=O)c1cccs1 +O=C(Cc1noc(-c2cccc(F)c2)n1)Nc1ccccc1F +COCC(C)(NC(=O)COc1ccccc1F)C(N)=O +O=C(Cn1c(=O)[nH]c(=O)c2ccccc21)NCc1ccccn1 +Cc1nc2ccccc2c(=O)n1CCC(=O)NCC1CCOC1 +Cc1nn(-c2ccccc2)cc1CNCCc1ccccn1 +Cc1ccn2c(=NC(=O)CNC(=O)CCC3CCCC3)[nH]nc2c1 +CCCCS(=O)(=O)NCC(=O)N1CCCC1c1cccc(C)n1 +c1sc(N2CCCC2)nc1C1COCCN1CC1CCC1 +Fc1cccc(-n2nnnc2SCc2nnc(-c3ccco3)o2)c1 +O=c1[nH]c2ccc(S(=O)(=O)NCc3ccccc3)cc2[nH]c1=O +CCCCC(=O)Nc1ccc(-c2nn3cnnc3s2)cc1 +O=C1CC(c2ccccc2)CN1Cc1cscn1 +CCOC(=O)C1=C(CN(C)CC)NC(=O)NC1c1ccccc1 +CC1Oc2ccc(NC(=O)c3ccc(OC(F)F)cc3)cc2NC1=O +COc1ccc(NC(=O)NCc2ncn(C)n2)c(OC)c1 +CCNC(=O)Cn1nc(C(=O)OC)c2ccccc2c1=O +O=C(NCCCc1ccccc1)c1nc(-c2cnccn2)no1 +O=C(c1ccc(Br)c(F)c1)C1CCC1 +Cc1nc(C(=O)NCC(O)c2ccc(F)c(F)c2)cs1 +CCN1CC23CN(C(=O)c4cccnc4)CC(CC2S1(=O)=O)O3 +O=C(Nc1cnn(-c2ncncc2N2CCOCC2)c1)C1CCC1 +COc1ccc(O)c2c1C(CCOc1ccccc1)NCC2 +CC(C)CCNC(=O)C(C)Oc1ccc(N)c(Cl)c1 +Clc1ccc(Cl)c(OCCN2CCOCC2)c1 +NS(=O)(=O)NCCOCc1ccc(Cl)cc1Cl +Cc1ccccc1-c1cnnc(NCc2cc(-c3ccccc3)[nH]n2)n1 +CCn1cnnc1-c1cccc(NC(=O)c2cc(C)n[nH]2)c1 +CCOC(=O)C1=C(C)C(c2csc(-c3cnccn3)n2)=NC1C +C=CCc1ccccc1OC(=O)C1Cc2ccccc2C(=O)O1 +COc1ccc(C(O)(O)Cc2ccccc2)cc1OC +CCCn1nccc1C(=O)Nc1ccn(CC#N)n1 +O=C(OCCn1cnc2ccccc2c1=O)c1cc2ccccc2o1 +Cc1cc(NC(=O)C(C)Nc2ccn(C)n2)ccc1Br +Cn1cc(N2C(=O)CC3C2CCN3C(=O)c2ccc[nH]2)cn1 +CC(NC(=O)N(C)C(C)c1ccncc1)C1CCCO1 +Cn1cc(NC(=O)C2CC(=O)N(c3ccc(F)cc3)C2)cc1C(N)=O +Cc1onc(-c2ccccc2)c1C(=O)Nc1ccc2c(c1)NC(=O)CO2 +Cc1cc(Cl)ccc1N(CC(=O)N1CCCC1)S(C)(=O)=O +Cc1noc(C(C)NS(=O)(=O)N2CCCC2c2ccc(C)o2)n1 +CSc1ccc(Cl)c(C(=O)N2CCCC(C)C2)c1 +CCOCCNC(=O)c1cn(C)nc1C(C)(C)C +O=C(NC1C=CC(CO)C1)N(CCCO)C1CCCc2ccccc21 +COc1ccc(Cc2c(OC)nc3n(c2=O)CCS3)cc1 +CCOc1ccc(C(=O)N2CCOCC2)cc1Br +CCN1CC2(CCC1=O)CCN(C(=O)Cc1cccc(C)c1)CC2 +O=C(CCn1cncn1)N1CCC(Oc2ccccc2)CC1 +CC(C)CNC(=O)C1CCCN(C(=O)c2ccn3cncc3c2)C1 +Cc1cc2ccccc2n1CCNC(=O)c1cnn2c1OCCC2 +CC1CCCN(C(=O)CNc2cccc(-c3nnnn3C)c2)C1 +C#CCC(NC(=O)c1cccc(N(C)C)c1)C(N)=O +Cn1cc(-c2nc(C(=O)NCc3cc[nH]n3)cs2)cn1 +Cn1ccc(C(=O)N2CCCC2c2nc3ccc(F)cc3[nH]2)cc1=O +Nc1ccccc1OCCCCSc1ncccn1 +CCNc1nc(OC)nc(Oc2ccc(OC(C)C)nn2)n1 +CCOCCCN(C)S(=O)(=O)c1ccccc1Br +O=C(NCc1ccnc(-n2cccn2)c1)C1CC(=O)N(CC2CC2)C1 +CC(=O)N1CCN(c2nc(C(F)(F)F)nc3ccc(C)cc23)CC1 +CCCc1cc(-c2nc(C)c(C(=O)NCC3CCCO3)s2)ccn1 +Cc1ccc(-c2ncco2)cc1NC(=O)NC1CCC(=O)N(C)C1 +Cc1cc(C(=O)CCC(=O)NCc2cccs2)c(C)s1 +CC(=O)c1ccc(NC(=O)N(C)Cc2nccs2)cc1C +COc1cccc(C2CCN2C(=O)c2ccc(C#CC(C)(C)O)cc2)c1 +NC(=O)C1CCN(C(=O)C2CCCCCC2)c2ccccc21 +CC1CCCC(NC(=O)CSc2n[nH]c(N)n2)C1C +COC(=O)CC(NC(=O)Nc1ccccc1)c1ccc(Cl)cc1 +Cc1ccc(CNC(=O)C(C)n2cncn2)s1 +Cc1cccc(C(=O)NCCc2nnc3n2CCCCC3)c1 +O=C(Nc1nccs1)C1CCN1C(=O)c1ccccc1 +CC(=O)c1cc2ccc(OC(=O)c3ccco3)cc2oc1=O +COc1ccccc1N1CC(C(=O)Nc2nccs2)CC1=O +O=c1c2nnc3c(-c4ccc(F)cc4)cnn3c2ccn1CCCO +CC(O)c1nc2cc(F)ccc2n1Cc1nccn1C +CCN(CC(=O)OC)C(=O)c1ccccc1COC +CNc1nc(-c2oc3ccccc3c2C2CC2)cs1 +Cc1ccoc1C(=O)Nc1cc(F)ccc1Cl +CCc1nc(CCNC(=O)N(C)Cc2ccccc2)sc1C +Nc1ncnc(Nc2ccc(C(F)(F)F)cc2)n1 +CCOC(=O)c1c(NC(=O)c2cc(C)oc2C)sc2c1CCC2 +O=C(Cn1cnc2cc(F)c(F)cc21)NCc1cccc(Cl)c1 +Cc1ccc(C2CC(C(F)(F)F)n3ncc(C#N)c3N2)s1 +Cn1nncc1CN1CCN(c2ccc(C#N)cc2F)CC1 +O=C1COC(=O)C1C(=O)Nc1ccc(OC(F)(F)F)cc1 +N#CC(CC(=O)N1CCc2ccccc21)C1CCCCC1 +COCc1ccc(-c2nc(Cc3ccccc3)n[nH]2)o1 +CC(CC#N)NC(=O)c1nc(C(C)C)ncc1Cl +Cc1noc(CNc2cccc(Cl)c2-n2cccn2)n1 +COc1cc(NS(C)(=O)=O)c(OC)cc1Br +CCNC(=O)CCC(C#N)c1ccccc1Cl +CCC1CN(CCC(=O)c2cccc(Br)c2)CCO1 +Cc1ccc(C)c(C(=O)NCCCn2cccn2)c1 +O=C(NCCNS(=O)(=O)c1cc(F)cc(F)c1)C1CC1 +Cc1cccc(C)c1OC1CCN(C(=O)C2CC(=O)N(C)C2)CC1 +CC(C)(C)c1cc(S(N)(=O)=O)c(OC2CC2)cn1 +Cc1sc2nc(-c3cnccn3)[nH]c(=O)c2c1-c1ccc(F)cc1 +O=c1[nH]c2ccccc2c(=O)n1CCCOc1ccccc1 +C#CCN(C)C(=O)c1nc(-c2ccoc2)n(-c2ccc(C)cc2)n1 +CC(C)c1cc(-c2nc(CC(=O)NC3CCCC3)no2)n[nH]1 +CC(=O)OCc1ccccc1-n1cccc1C(C)=O +CCCC1CN(C(=O)c2cccc(Nc3cnn(C)c3)c2)CCO1 +Cc1nn(Cc2nc(-c3ccc4c(c3)OCO4)no2)c(C)c1Cl +Cc1ccc2c(c1)SC(C(=O)Nc1cnn(C)c1)C2 +CN(CC1CC1)C(=O)C1CCC(=O)N1Cc1cccs1 +CC(=O)Oc1ccc2c(c1)C(OC(C)=O)OC2OC(C)=O +CCCCSc1nc2n(n1)C(c1ccco1)C(C(=O)OC)=C(C)N2 +COC(=O)C1(C)CCN(S(=O)(=O)c2ccc(C)cc2)C1=O +Cc1csc(N2CCCN(C(=O)c3ccc(C)c(C)c3O)CC2)n1 +CCCCNC(=O)n1ccc(C(=O)Nc2ccc(OC)cc2)n1 +CCN(CCC(O)c1ccccc1)CC(F)(F)F +CCCNC(=O)c1c(C)nn(Cc2ccccc2Cl)c1C +O=C(NCCc1ccncc1)c1cnn(-c2ccccc2)n1 +Cc1cc(C)cc(Nc2cc(C)n3c(=O)n(C)nc3n2)c1 +CC(C)n1c(C(=O)N2CCN(C)CC2)cc2sccc21 +CC1CN(C(=O)NCc2cccc(F)c2)CCC1(O)C1CC1 +COCC(C)NC(=O)CSc1nc2ccccc2c2nc(C)nn12 +COc1cccc(C=Cc2nc(C#N)c(N(C)C)o2)c1 +CCC(C(=O)N1CCC(c2nnc(C(C)C)o2)CC1)c1ccccc1 +O=C(CCNC(=O)NC1c2ccccc2CC1O)NC1CCCC1 +Cc1cc2c(c(=O)[nH]1)C(c1ccccc1)CC(=O)O2 +COc1cccc(CNC(=O)Cc2cn3ccsc3n2)c1 +Cn1nc(C(=O)N2CCC(CO)C(O)C2)c2c1CCCC2 +CC(NC(=O)Cc1cccc(F)c1F)c1ccc2c(c1)OCCO2 +N#Cc1cc(CNc2cccc(F)c2F)ccc1F +O=C1COc2ccc(Sc3ncccn3)cc2N1 +CCC(=O)Nc1ccccc1OCc1cc(=O)n2cc(C)ccc2n1 +CN(C)C(=O)c1ccc(NCc2nc(-c3ccsc3)no2)cc1 +O=C(CSc1cn[nH]n1)N1CCc2ccccc2C1 +CCOc1ccc(Nc2nc(SC)ncc2CO)cc1 +CCOC(=O)c1nc(NCc2ccc(F)cc2)c2c(C)noc2n1 +COc1cccc(C(O)c2ccc(F)cc2)c1F +Nc1nc(-c2ccc3c(c2)OCO3)nc2c1CCC2 +NC(=O)c1ccc(C(=O)OCc2cc(Cl)c3c(c2)OCO3)cc1 +CCc1noc(CNc2ccc(Cl)cc2C(O)c2ccccc2)n1 +Cc1c(F)ccc2c1C(C1CC(=O)N(C(C)C)C1)NCC2 +O=C(NCc1ccc[nH]1)c1ccc(N2CCCCC2=O)cc1 +COC(=O)c1cccc(C(=O)OCCc2c(C)n[nH]c2C)c1 +O=C(CNc1ccc(F)cc1OCCO)Nc1ccc(F)c(F)c1 +Cc1nc2nc(C)c3c(=O)n(Cc4ccco4)ccc3n2n1 +O=C(C1CCCC1)N1CCN(S(=O)(=O)c2cccs2)CC1 +Cc1cccc(CNC(=O)C2CCN(c3cn[nH]c(=O)c3)CC2)c1 +CNC(=O)COc1ccc(OCc2nc(C)cs2)cc1 +Cc1cccc2c(=O)n(CC(=O)N3CCC(C)CC3)cnc12 +CCCOc1ccc(S(=O)(=O)NCC2(O)CCOCC2)cc1 +Cc1cccc(N2CCN(C(=O)c3cncn3-c3ccccc3)CC2)c1 +COc1ccc(CCNC(=O)CCC#N)c(OC)c1 +Cc1nc(NC(=O)N(C)C(C)c2ccncc2)oc1C +COc1ccc(OC)c(C(C)NC(=O)Nc2cnccc2C)c1 +Nc1ccc(C(=O)OCCCC2=NC3C=CC=CC3=N2)cc1 +COCC(c1cccc(C(F)(F)F)c1)N(C)C(=O)c1cc(C)no1 +C=CCOCc1cncc2c1CCN(C(=O)c1ccsc1)C2 +COc1cc(CNC(=O)CC(C)(C)C)ccc1O +CSc1ccc(Cl)c(C(=O)N(C)Cc2nc3ccccc3[nH]2)c1 +CC(=O)NC(C)C(=O)N1CCN(c2cc(C)nc(C(C)C)n2)CC1 +COc1cc(F)c(C(=O)NCCc2csc(C)n2)cc1OC +COc1ncccc1NC(=O)N(Cc1ccc(C(N)=O)cc1)C1CC1 +CCCc1nnc(SCC(=O)Nc2cccc3ccccc23)n1N +O=C(c1ccco1)N1CCN(Cc2ccsc2)CC1 +Cc1ccc2c(NC(=O)Cc3noc4ccccc34)cccc2n1 +CN(C(=O)c1ccccc1NC(=O)C1CCC1)C1CCCCC1 +N#Cc1ccccc1N1CCN(Cc2n[nH]c(=O)[nH]2)CC1 +Cc1nc(CN2CCN(c3ccccc3-c3ccccc3)C(=O)C2)no1 +CC(C)c1nc2cc(Cl)c(Cl)cc2n1CCO +COCc1cc(NCc2nc3c(C)cccc3o2)ncn1 +CN(C)c1nc(C2CCN(C(=O)C3CCCO3)C2)cc(=O)[nH]1 +CCNC(=O)NC(C)c1cccc(OC(C)C)c1 +Cc1ccc(C)c(CC(=O)NCC2(O)CCOCC2)c1 +CC(C)(C)OC(=O)N1CC(Oc2ccccn2)C1 +O=C(CCn1ccnc1)N1CCN(c2cccc(Cl)c2)CC1 +O=C(NCC(=O)N1CCC1)c1sc2ccccc2c1Cl +C=CCOC(=O)C1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1 +CC(=O)Nc1ccc(NC(=O)NC2CCc3c(Cl)cccc32)cc1 +Cc1cc(C(=O)Nc2cc(Cl)ccc2N2CCCCC2)no1 +Cc1cnc(NC(=O)c2ccc(F)cc2Cl)s1 +OCC#Cc1csc(-c2nccn2-c2cccc(-c3ccn[nH]3)c2)c1 +Cc1ccc2ncc(C(=O)NC3(c4ccccc4)CCCC3)c(=O)n2c1 +C=CCOc1cccc(NC(=O)CC2OC(=O)c3ccccc32)c1 +CCC1CCC(NC(=O)c2cccc(COC)c2)CC1 +Cc1cccc(C(=O)Nc2c(-n3cnnc3)nn(C)c2C)c1 +C=CCN(CC=C)C(=O)c1onc(-c2ccccc2C)c1N +O=C(CSc1nc2ncccn2n1)N1CCc2ccccc21 +Cc1cc(Cl)c(C)c(S(=O)(=O)N(C)CCC#N)c1Cl +COc1cc(F)c2c(c1)C(C1Cc3ccccc3N1)NCC2 +CN(C)C(=O)c1cccc(OCc2ccc(F)cc2Cl)c1 +O=C(CSc1nnc(-c2ccncc2)o1)N1CCCCC1 +Nc1cc(=O)[nH]c(SCC(=O)Nc2ccc3ccccc3c2)n1 +CCN(CC)C(=O)CN(C)c1nccc(Oc2ccc(F)cc2)n1 +Cc1ccc2c(Cl)c(C(=O)NCc3ccncc3)sc2c1 +CC(=O)Nc1cccc(NC(=O)N(CC(F)F)C(C)C)c1C +CCCc1noc(CCCC(=O)N2CCn3c(nnc3C(C)C)C2)n1 +O=C(NCc1ccccc1)c1ccc2[nH]nnc2c1 +COc1ncccc1CNC(=O)NCC(C)CO +CC(=O)Nc1ccc(N=c2cc(C)[nH]c3ccc(F)cc23)cc1 +COC(C)C(=O)Nc1ccc(F)c(S(=O)(=O)NC(C)(C)C)c1 +COc1cc(C(O)C(Cl)(Cl)Cl)cc(OC)c1OC +COc1c(Cl)cccc1NC(=O)c1cnn(-c2ccccn2)c1C +C#CC(CC)(CC)NC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 +CC(=O)Nc1cccc(C(=O)N(C)CCC(F)(F)F)c1 +O=C(NCCc1ccccn1)NC(c1ccc(F)cc1)C1CCC1 +Cc1ccc(Br)cc1-c1cc(N)on1 +CCOC(=O)c1ccc(S(=O)(=O)N(CC)CC)cc1 +Cc1cc(N2CCC(Sc3nncc4ccccc34)C2=O)n(C)n1 +N#Cc1nccnc1Sc1nnc(C2CC2)n1-c1ccccc1 +O=C(Cc1ccccc1)NCCC(=O)N1CCc2cc(F)ccc2C1 +CC1Oc2ccc(NC(=O)c3nccnc3N)cc2NC1=O +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2ccccc2F)c1C +N#Cc1cccc(C(=O)N2CC3CCC2CN(C(=O)C2CCC2)C3)c1 +Cc1nn2c(=O)c(C)c(C)[nH]c2c1-c1ccccc1 +Cc1ccc(NC(=O)c2cccc(Nc3cnn(C)c3)c2)cc1C(N)=O +COc1ccc(NCC(=O)Nc2cccc(Br)c2)cn1 +CCC(CC)C(=O)NCC1CCN(S(C)(=O)=O)CC1 +COc1cc(NC(=O)NCC2CCCC2O)ccc1Br +CCNC(=O)C(C)OC(=O)c1cc(C(C)=O)c[nH]1 +COC(=O)Nc1cccc(C(=O)Nc2ccc3nc(C)sc3c2)c1 +O=c1c(=Cc2ccccc2Cl)sc2nc(-c3ccncc3)nn12 +CN(Cc1nc(C2CC2)no1)C(=O)c1cc(-c2ccccc2O)n[nH]1 +COCCc1noc(-c2ccc(N(C)Cc3ccon3)nc2)n1 +NC(=O)C(NCc1ccccc1-n1cccn1)c1ccccc1 +CCN(CC(F)(F)F)S(=O)(=O)c1ccc(C)cc1 +Cc1cc(F)c(S(=O)(=O)NC(C)CCn2cncn2)cc1F +CS(=O)(=O)c1ccccc1NC(=O)CCC1CCCC1 +Cc1nn(-c2ccccc2)c(C)c1CN(C)C(=O)C1CCCO1 +OCc1nc2cc(Cl)ccc2n1CC1CCCO1 +COCCCC(=O)Nc1cccnc1-n1ccnc1C +Cc1cccc(CC(=O)Nc2ccc(-c3cn4cccnc4n3)cc2)c1 +O=C(Cn1c(=O)[nH]c2ccccc21)Nc1nc(C2CC2)cs1 +CC(C)CNC(=O)c1ccc(OCC(C)C)c(N)c1 +OCCN1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 +COc1ccccc1-n1cnnc1S(=O)(=O)Cc1ccon1 +CC(C)CC(C)N(C)c1nc2sccn2c1CO +COCCNC(=O)CNC(=O)c1cnn(C)c1-n1c(C)ccc1C +CCC(=O)c1ccc2c(c1)N(C(CC)C(=O)OC(C)C)C(=O)C(C)O2 +O=C(NCc1ccccn1)Nc1cc(-c2ccccc2)nn1CCO +Cc1cnn(CCC(=O)Nc2ccc(OCc3nc(C)no3)cc2)c1 +CCC(C)c1ccccc1OCC(=O)Nc1ccc(N)cc1OC +Nc1cc(Cl)ccc1NC(=O)c1ccc(O)cc1 +C1CCCC(OCCSc2nnnn2C2CCOCC2)CC1 +Cc1nnc(SCC(=O)Nc2ccc(Cl)cn2)o1 +CCc1cc(NC(=O)C2CC(=O)N(C)C2c2ccc(F)cc2)n(C)n1 +CCOc1ccc(C)cc1S(=O)(=O)N1CCCCCC1 +COCc1nc2ccc(NC(=O)c3ccc(Cl)cc3)cc2[nH]1 +CCCCN(Cc1ccc(F)cc1)C(=O)c1cc[nH]n1 +COc1ccc(C(=O)Nc2cccn3c(C)nnc23)cn1 +O=C(Nc1ccc2cn[nH]c2c1)c1cccc(Cl)c1 +Cc1c(N)cc2c(CC(=O)N(CCO)CCO)noc2c1C +O=c1[nH]nc(SCC(F)(F)F)n1CC1CCCO1 +Cc1noc(CNC(=O)NCc2cc(Br)ccc2F)n1 +Cc1cc(CNc2ccccc2C(N)=O)ccc1F +C=CCN(CC=C)S(=O)(=O)c1cncc(N)c1 +COc1ccc(OCCCNC(=O)c2c[nH]c3cccc(F)c23)cc1 +COc1cc(C)c(C)cc1C(O)CNC(=O)c1ccc(C)cc1 +O=C(NCCCOCC1CCOC1)NC1CCCOc2ccccc21 +CC(=O)N1CCN(C(=O)c2cccc(Nc3ncccn3)c2)CC1 +COc1cccc(-c2cncc(C3CCN(C(C)=O)CC3)n2)c1 +COc1ccc(N2CCN(CC(=O)NCC3CCCO3)C2=O)cc1 +COc1ccc(C)cc1-c1csc(NC(=O)C2CC2)n1 +CCC1CN(c2cc(C)nc(N3CCCC3)n2)CCC1(C)O +CC(C)CNC(=O)Cc1nnc(-c2ccccc2)o1 +CC1(NS(=O)(=O)c2ccc3c(c2)CCC3)CCCC1 +CC(C)NC(=O)Nc1ccc(NC(=O)C2CC2C)cc1 +CCC(C)(C)NC(=O)CCc1nc(C(C)(C)C)no1 +Cc1nc(C(C)(C)NC(=O)CN(C)C(=O)OC(C)(C)C)sc1C +CC(C)(C)OC(=O)CSc1nnnn1C(C)(C)C +COC(=O)C1(NC(=O)c2cc(C)ccc2C)CCCC1 +CCc1ccsc1C(=O)NCc1ccc(-n2ccnc2C)nc1 +CCC(=O)N1CCCN(C(=O)NCc2cnc(C)s2)CC1 +CC(C)c1cc(C(=O)Nc2ccc(C(N)=O)cc2)n(-c2ccccc2)n1 +CC(Sc1nnc(CCC(N)=O)n1C)c1ccc(F)cc1 +CC1=C(C(=O)Nc2ccccc2)C(c2ccccn2)n2ncnc2N1 +Cc1cc(C)n(CCCNC(=O)c2cccc(F)c2F)n1 +CC(CCc1ccccc1)NC(=O)CSc1ncn[nH]1 +O=C(NCCc1ccccc1)c1ccc2sncc2c1 +Cc1csc(C2CCCN(C(=O)c3ccc(C#N)c(C)n3)C2)n1 +Cc1cccc(OCc2nnc(SCCC(C)(C)C#N)o2)c1 +O=C1CCn2c(CNc3ccc(Br)cc3)ccc21 +COc1cc(C(=O)N2CCCC2(C)C)cc2c1OCCO2 +CC1NCc2ccccc2C1C(=O)N1CCN(C)CC1 +O=C(NCCO)c1csc(-c2cccc(Cl)c2)n1 +O=C(CN1CCCCCC1=O)OCc1ncc(-c2ccccc2)o1 +O=C(c1cn(Cc2ccccc2)nn1)N1CCOC2CCCCC21 +Cn1cc(S(=O)(=O)NC2(c3ccc(Cl)cc3)CC2)cn1 +CC(=O)N1CCc2cc(NC(=O)N(C)Cc3ccccc3F)ccc21 +C#CCC(C)OC(=O)c1ncn(-c2ccccc2)n1 +CCOC(=O)C1=C(CN(C)Cc2cnn(C)c2)NC(=O)NC1 +Cc1cc2c(o1)c1cnn(CC(=O)NCC3CC3)c(=O)c1n2C(C)C +CCC(C)N(C)C(=O)Nc1ccccc1-n1cccn1 +N#Cc1cc(NC(=O)c2ccc3c(c2)CCO3)ccc1F +COCCN1C(=O)c2ccccc2NC1(C)c1ccc(Cl)cc1 +Cc1[nH]ncc1CCCNC(=O)Cn1nc2n(c1=O)CCCCC2 +COc1cccc(-c2cn3c4c(sc3n2)CNCC4)c1 +Clc1cccc(NCc2cnc[nH]2)c1-n1cncn1 +O=C(Cn1cncn1)N1CCN(c2ncnc3[nH]cnc23)CC(O)C1 +COc1ncnc2c1CCN(C(=O)Cc1ccc(F)cc1)C2 +Nc1ccc2[nH]cc(C(=O)NCC3CCCO3)c2c1 +CC(C)(CNC(=O)NCC1(C2CC2)CC1)c1ccncc1 +C=CCOc1ccc(CN2CCOC(C(=O)OC)C2)cc1 +O=C(NCCSc1c[nH]c2ccccc12)c1cnn2c1OCCC2 +O=C(c1cc2scnc2[nH]1)N1CCN(C(=O)c2ccco2)CC1 +COc1ccc(C(C)(C)CNC(=O)C2(C)CCOCC2)cc1OC +O=C(CCCc1nc2ccccc2o1)Nc1nnc(-c2ccccn2)[nH]1 +Cc1ccc(S(=O)(=O)NCc2nc3nc(C)cc(C)n3n2)cc1 +COc1ccc(C)cc1NC(=O)c1cc(C)cc(C)n1 +Cc1nc(CCc2ccc3c(c2)OCCO3)sc1CO +CCc1cc2c(NCc3ccccc3OC)ncnc2s1 +CC(=O)c1nc2ccc(F)c(F)c2n1C1CCCC1 +CC1CCc2n[nH]c(-c3nc(C4CC4)nn3-c3ccccn3)c2C1 +Cc1cccnc1Nc1ncnc(NC(C)(C)C)c1N +O=C(Nc1ccc2nc[nH]c(=O)c2c1)C1COCCO1 +CC(C)NC(=O)CCc1ccc(NC(=O)c2ccc(F)cc2)cc1 +c1ccc2c(c1)N1CCCN=C1N2CCN1CCOCC1 +CCOC(=O)CN(C)C(=O)c1cn(C)nc1-c1ccc(F)cc1F +CCOC(=O)N1CCCC(C(=O)N(CC)c2cccc(F)c2)C1 +O=S(=O)(NCc1ccncc1)c1ccc2c(c1)CCC2 +CC(=O)c1ccc(NCC(=O)Nc2cc(C)on2)cc1 +COCCN(CC(C)C)C(=O)c1cc(C)nc2c1cnn2C(C)C +O=C(CCS(=O)(=O)N1CCNCC1)Nc1ccc(F)c(F)c1 +CC(C)c1cc(N)cc2c1OC(c1ccccc1)C(=O)N2C +COc1ccc(NC(C)=O)c(NC(=O)C(C)Oc2cccc(F)c2)c1 +CC(Nc1ncnc2c1cnn2CCO)c1ccc2c(c1)OCO2 +Cc1ccc(F)cc1NC(=O)c1cc(C(F)(F)F)n[nH]1 +COc1cc(CNC(=O)c2cnccn2)ccc1OC(F)F +O=C(c1csnn1)N1CCN(c2ncccc2Cl)CC1 +Cc1nc(CC(=O)NCc2ccco2)sc1-c1ccccc1 +O=C(C1CCCCC1)N1CCn2c(cccc2=O)C1 +O=C(NCCC1=CCCCC1)NCC(O)c1c(F)cccc1F +CCOC(=O)c1c(C)oc(C)c1S(=O)(=O)N1CCOCC1 +CCCCn1c(=O)c2ccccc2n(CC(=O)NC2CCCC2)c1=O +O=C(CCn1cnc2ccccc21)NCC1COC2(CCCC2)O1 +O=C1COc2cc(NC(=O)c3csc4c3CCCC4)ccc2N1 +O=C(Oc1ccccc1)c1cccnc1OCC(F)F +O=C(Nc1ccc2nc(C3CCCO3)[nH]c2c1)c1ccncc1Cl +COc1ccccc1NCC(O)c1c(F)cccc1Cl +CC(=O)c1ccc(C#CCNC(=O)c2cc(-c3ccccc3)on2)cc1 +Cc1c(C)n(CCCO)c2ncn3nc(-c4ccc(F)cc4)nc3c12 +Cc1ccc(NCC(=O)N2CCCCC2)cc1F +CCSc1cccc(NC(=O)NCc2csc(NC)n2)c1 +CN(C)C(=O)C1CCN(C(=O)c2ccc(C(C)(C)C)cc2)CC1 +Cc1nn(C(C)(C)C)cc1C(C)NC(=O)N1CCNC(=O)CC1 +CCCn1c(CNCC(=O)OC)nc2ccccc21 +CCCCN1C(=O)C(=O)c2cc(Br)ccc21 +Cc1nc2sccn2c1CNc1c(F)cccc1F +O=C(NCCS(=O)c1ccccc1)c1ccc(C(F)(F)F)cc1 +COCc1nnc(NC(=O)Cn2sc3ccccc3c2=O)s1 +O=C(NCCNC(=O)c1ccccc1O)NCc1ccccc1Cl +CC(C)NS(=O)(=O)c1ccc(C(=O)N(C)c2ccccc2)cc1 +Cc1ccc(C)c(C2CN(Cc3ccnn3C)C(C)CO2)c1 +CC(NC(=O)COc1cccc2cccnc12)c1ccc(F)cc1F +COCCCNC(=O)Cc1cccn1-c1ccc(C)cc1 +COc1ccc(-c2cnn(CCC(C)C)c(=O)c2CO)cc1 +Cc1cccc(NC(=O)C(O)c2ccc(Cl)cc2)c1C +CCOc1ccc(NC(=O)Nc2ccccc2C(N)=O)cc1 +O=S(=O)(NCC1CCC1)c1cc(Cl)ccc1Cl +O=c1c2ccc(F)cc2ncn1CC(O)CCc1ccccc1 +Cc1nc2nc(C)c3c(=O)n(-c4ncn[nH]4)ccc3n2n1 +COc1ccc(S(=O)(=O)NCc2cccnc2)cc1NC(C)=O +Cc1ccc2c(CC(=O)NCCCC(N)=O)coc2c1 +Nn1ccc2nc3ccn(Cc4ccccn4)c(=O)c3cc2c1=O +Cc1c(N)cccc1NC(=O)Cn1cc(Br)cn1 +Cc1cccc(OCC(=O)N2CC(C)C(C)(O)C2)c1 +CCNC(=O)CSc1nc2cc(Cl)c3cccnc3c2o1 +CCC(C)N(CCOC)C(=O)c1ccc(N)nn1 +CCn1ccc(C(=O)Oc2ccc(Cl)cc2)n1 +O=c1c2ccccc2nnn1CSc1nccn1Cc1ccccc1 +Cc1nc2cc(C(=O)N3CCC(CCn4cccn4)CC3)ccc2[nH]1 +Cn1ccnc(NC(=O)c2cccc(-c3noc(C4CC4)n3)c2)c1=O +Cc1oc(C)c(C(=O)Nc2ccc(S(=O)(=O)NC3CC3)cc2)c1C +Cc1ncsc1COC(=O)CCC(=O)c1ccc(F)c(F)c1 +N#CC(C(=O)c1cccs1)c1nc(=O)c2ccccc2s1 +Cn1nnnc1SCC(=O)c1ccc2c(c1)CC(=O)N2 +CC(C)(C)NC(=O)c1cccc(NC(=O)C2CC3CCC2O3)c1 +Cc1nnnn1C(Cc1ccc(F)cc1)C(=O)N1CCN(C)CC1 +CCn1ccnc1N1CCN(C(=O)c2cccc(OC)c2)CC1 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+CC(C)CNC(=O)C1(NC(=O)c2ccnc3c2OCO3)CCCC1 +COc1cccc(-c2nnn(CC(F)(F)F)n2)c1 +COc1ccc(C(=O)N(C)Cc2cccc3ccccc23)cc1OC +CC(C)(C)c1nnc2sc(-c3cccc(N)c3)nn2c1=O +COc1ccc(OCCn2cc(CCO)nn2)cc1 +COc1ccnc(Oc2ccc(Cl)cc2)c1C(N)=O +CC(OC(=O)c1cccc(F)c1)c1nc2ccccc2c(=O)[nH]1 +Cc1cc(NC(=O)C2CCCN(c3cnccn3)C2)no1 +CC(C)NC(=O)N(C)C1CCN(c2ccc(F)cc2)CC1 +Cc1c(F)cccc1-c1ccc(CN(CCC#N)Cc2ccccn2)o1 +CCOc1ccccc1-c1cn(-c2ccc(N)cc2Cl)nn1 +Cc1c(NC(=O)NCC(=O)NC2CC2)cccc1OCC(F)(F)F +COc1cc(C)ccc1OC(=O)C(C)c1cccs1 +CCOc1ccc(F)c(C(=O)OC(C)c2cccnc2)c1F +O=C(Nc1nncs1)c1cnc(-c2ccccc2)nc1 +CC(CO)C(C)NC(=O)NCc1ccccc1OC1CCC1 +COC(=O)C(C)(C)NC(=O)Cc1ccc(-n2cccc2)cc1 +CCN(C(=O)NCCOCC(F)(F)F)C1CCCC1 +Cc1cccc(SC(C)c2nc(N)nc(N(C)C)n2)c1 +NC(=O)C(Nc1cnc2cc(F)c(F)cc2n1)c1ccc(Cl)cc1 +Cc1ccsc1CCNC(=O)C1CCCCn2nnnc21 +CC(C)c1cc(C(=O)N2CCN(Cc3cccs3)CC2)n(C)n1 +CC(=O)NCCn1cnc2sc(C)cc2c1=O +O=C(c1cc(-c2ccc(O)cc2)n[nH]1)N1CCC(c2ccncc2)CC1 +CNc1ccc(S(=O)(=O)NC(C)C2CCCO2)cc1 +CCC(=O)Oc1cccc(NC(=O)c2cccc(OC)c2)c1 +CCCOc1ccc(C(O)C(C)C(=O)OC)cc1 +COC(=O)c1ccc(C(=O)NCc2ccccc2Cn2cccn2)cc1 +O=C(Cn1nnc2ccccc2c1=O)NCC1CC2C=CC1C2 +CCCN(C)C(=O)c1cc(S(N)(=O)=O)c(C)cc1C +CCOc1ccc(NC(=O)C(N)c2ccccc2)cc1 +Cc1cc(C)c(C(=O)NC(C)c2ccc(C)c(F)c2)c(=O)[nH]1 +N#Cc1nc(COc2ccccc2F)oc1N1CCOCC1 +CCN(Cc1ccc(OC)cc1)C(=O)CCn1ccccc1=O +Cc1ccc(C(C)NC(=O)c2cn(CC(N)=O)nn2)cc1F +CC(C)NC(=O)CSc1nnc(-c2cccs2)n1N +CN(C)c1ccc(NC(=O)COCC2CCCO2)nc1 +CCC(=O)Nc1nnc(-c2ccc(OC)c(OC)c2)o1 +O=C1N(CCOc2ccccc2)c2ccccc2C12OCCCO2 +CC(=O)c1c(C)[nH]c(C(=O)N2CCc3cc(F)ccc3C2)c1C(C)C +O=S(=O)(Nc1ccccc1Cl)c1ccc2c(c1)CCN2 +CCc1nnsc1C(=O)NCc1ccc(OC)cc1 +CCN(CC)C(=O)c1c(C)nc(N)nc1-c1cc(C)no1 +OC(Cn1nnc2ccccc21)c1ccc(Cl)cc1 +Cc1nc2ccc(NC(=O)NCc3nc4ccccc4s3)cc2o1 +CC1=C(C(=O)Nc2cccnc2)C(c2ccc(O)cc2)n2nnnc2N1 +CSc1ccccc1C(=O)NCc1ccccc1Cn1cccn1 +COc1ccc(OC)c(N2CCN(C(=O)CC(C)(C)C)C(C)C2=O)c1 +O=C(NCc1cn[nH]n1)c1cccnc1N1CCCC1 +COc1cccc(CC(=O)Nc2ccc(S(C)(=O)=O)cc2)c1 +CS(=O)(=O)NCC1OCC2CCN(C(=O)c3ccco3)CC21 +Cc1ccc(-c2ncco2)cc1NC(=O)CCc1c(C)nn(C)c1C +COC(=O)c1cccc(NC(=O)c2cncc(Br)c2)c1 +CN(C)C(=O)C1CCCN1c1ncnc2ccccc12 +CC(C)Cn1cc(C(=O)N2CCC(C(N)=O)CC2)c2ccccc21 +CC(C)(C)CC1CCCN1C(=O)c1ccc2[nH]cnc2c1 +CC(C)CCN1CC2(CCCN(c3ccc(C#N)cn3)C2)CCC1=O +CC(C)(C)c1nc2cc(Br)cnc2n1CCCO +CC(=O)NCCNC(=O)NCc1ccnc(-n2cccn2)c1 +O=C(NCC1(CO)CC1)c1nc2ccccc2s1 +CCC(C(=O)OC)N1C(=O)C(CC)(CC)Oc2cc(N)ccc21 +COc1ccccc1C(=O)Nc1cc(-c2ccco2)no1 +CCN(C)C(=O)CNc1cc(Br)ccc1OC +Cc1cnn(CC(=O)NCc2ccc(Oc3ccc(F)cc3)cc2)c1 +COc1ccc(C(=O)NC2(C#N)CCCC2)c(OC)c1 +CCNc1ncnc2onc(-c3ccc(Cl)cc3)c12 +CCOC(=O)N1CCN(C(=O)COc2ccc(Cl)cc2C)CC1 +CCc1cc2c(=O)n(CC(=O)Nc3ccc(C#N)cc3)cnc2s1 +Cc1cccc(N2CCN(C(=O)c3cnn(C(C)(C)C)c3)CC2)c1 +Cc1nccn1Cc1cccc(CNC(=O)CCc2ccccc2)c1 +COC(=O)c1cc(NC2CCOCC2)cc(C)c1C +Cn1nc(OCC(=O)NC(C)(C)C)cc1C(F)(F)F +O=C(Cc1ccc[nH]1)Nc1ccc(NC(=O)NCC2CCCO2)cc1 +COC(=O)CNC(=O)C(C)Sc1nccn1-c1ccc(C)cc1C +O=C1CCCN1CCCOc1ccc(Cl)cc1Cl +COc1ccc(NC(=O)CSc2nnc(C3CC3)n2N)cc1 +Cc1ccc2cc(C(=O)Nc3cccc(CO)c3)ccc2n1 +CC(C)(C)n1nc(C(=O)OCC2CC(=O)N(C3CC3)C2)cc1C1CC1 +CCN(C)C(C(=O)Nc1ccc(CNC(N)=O)cc1)c1ccccc1 +Cc1ccc(-c2noc3c(NCc4ccco4)ncnc23)cc1 +CC(C)Cc1ncc2c(n1)CN(C(=O)CSc1ccccc1)C2 +CC(=O)c1c(F)cccc1NCc1cccc(OCC(=O)N(C)C)c1 +CCc1cccc(CC)c1NC(=O)c1cc(C)on1 +CCNC(=O)n1cc(-n2cncn2)c(-c2ccccc2)n1 +CC(C1CC1)N(CC(F)(F)F)C(=O)COc1cccc(C#N)c1 +CCc1nc(N2CCC(O)C(O)C2)c2cnn(C)c2n1 +CCC(Nc1nc(C2CCCC2)nc2c1cnn2C)c1nc(C)no1 +Cc1cccc(NC(=O)C(C#N)Cc2cccc(O)c2)c1 +COc1cc(C(=O)NC(C)c2ccncc2)cc(OC)c1OC +COc1cccc(-c2nnc(NC(=O)c3snnc3C)o2)c1 +CC1CCCC(CNC(=O)CCn2cnc3sccc3c2=O)C1 +Cc1ccc(-c2noc(Cn3nnn(-c4ccccc4)c3=O)n2)cc1 +CC(=O)NC1CCCN(C(=O)c2ccc(NC3CC3)nc2)C1 +CC(C)c1nnc(CCOc2cccc(N)c2)s1 +CC(CC(N)=O)C(=O)Nc1ccc(Cl)cc1Cl +N#Cc1cccc(C(=O)NCC(O)c2ccoc2)c1 +CC(=O)c1ccc(NC(=O)c2nnn(-c3ccccc3)c2N)cc1 +Cc1ccc(C)c2c(C)c(C(=O)NCCCC(N)=O)oc12 +C=CCNC(=O)C(C)OC(=O)c1ccc(-n2cccn2)cc1 +COc1ccc(CCC(=O)N2CCCC2c2ccc[nH]2)cc1 +Cc1ccc(O)c(NC(=O)c2ccc(NC(=O)C3CCCO3)cc2)c1 +CCCC(C)(C)NC(=O)c1ncn(-c2ccccc2)n1 +Nc1nn(-c2ccccc2)cc1-c1nc2ccccc2o1 +Cn1c(=O)c2cc(C(=O)NCCC3=CCCCC3)cnc2n(C)c1=O +Cc1cc(C(=O)N2CCc3onc(CN4CCOCC4)c3C2)[nH]n1 +Cc1onc(N)c1S(=O)(=O)N1CCN(c2ncccn2)CC1 +CCOCc1ccc(NC(=O)N(C)CCC#N)cc1 +O=C(NCCc1ccc(F)cc1)c1ccn(-c2ccccc2)n1 +CCCc1noc(C2CCCN(C(=O)C3CCCO3)C2)n1 +CCC(=O)N1CCN(c2nc(C)c3c(c2C#N)CCCC3)CC1 +CC(C)=CCN1C(=O)C(=O)c2cc(Br)ccc21 +Cc1cc(NC(=O)c2ccc(OCc3ccccc3C#N)cc2)[nH]n1 +COC(=O)c1ccc(OCC(O)CN2CCc3ccccc32)cc1 +Cc1ccc(-c2noc(CNC(=O)NC(C)(C)C)n2)cc1 +CC(=O)c1ccc(F)cc1-c1cc(N)nc2[nH]ccc12 +CN(CC(=O)Nc1cccc(OC(F)F)c1)c1ncnc2[nH]cnc12 +CN1CCN(C(=O)C(C)(C)C)c2cc(Br)cnc21 +CC(C)CCCCNC(=O)c1ccccc1-n1cnnn1 +O=c1ccnc(-c2cccc(Br)c2)[nH]1 +O=C(c1ccsc1)N1CCn2nnc(COc3cccnc3)c2C1 +CCOc1cc(NC(=O)C(C)NC(=O)c2ccccc2)ccc1OC +CC(C)(C)OC(=O)CSc1nc(N)cc(=O)[nH]1 +Fc1cc2c(c(F)c1F)CCNC2c1cnccn1 +CC(C)NC(=O)Cn1cnc2c(sc3ccccc32)c1=O +Cc1ccc(OCc2nc3cc4c(cc3[nH]2)OCCO4)cc1 +O=C(NCc1cc[nH]n1)c1ccc2ncccc2c1 +CCCCNC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +CCC(CO)NC(=O)c1sc(-c2cccs2)nc1C +COc1cc(C#N)ccc1OCC(=O)NC(C)c1ccccc1 +C#CCN1CCN(CC(=O)NC2CCCCNC2=O)CC1 +CC(CNC(=O)c1cnc2sccn2c1=O)c1ccc(F)cc1 +COc1cccc(C(=O)NCc2ccc(C)cc2)c1OC +CC(OC(=O)CN1C(=O)COc2ccccc21)C(=O)NC(C)(C)C +O=C(Nc1nnc(C2CCC2)s1)c1ccc2c(c1)OCCCO2 +Cc1n[nH]c(C2CN(Cc3csc(C4CCCCC4)n3)CCO2)n1 +COc1cc(NC(=O)n2ncc3ccccc32)cc(OC)c1OC +O=C1CCC2(CCCO2)CCN1Cc1cc(F)c(F)c(F)c1 +CCOC(=O)c1cn(CC(=O)Nc2ccc(CC)cc2)nn1 +N#Cc1ccc(NCC(O)c2ccc3c(c2)OCCCO3)cc1 +COc1ccc(Cc2nncn2-c2ccc(F)cc2F)cc1 +CCN(CC)C(=O)NC1CC(=O)N(C)C1c1ccc(Cl)cc1 +CC(C)(O)c1nnc(C(N)c2c(F)cccc2F)o1 +Cc1cc(C(=O)CCCC(=O)NC(C)C)ccc1F +CCCn1c(C)nnc1SCc1nccn1C(F)F +CCOC(=O)c1cnn(C)c1C(=O)NCC(F)(F)F +N#Cc1nccnc1NC1CCCN(CCO)C1=O +CC(C)(C)NS(=O)(=O)c1cnc(N)c(Cl)c1 +COc1cc(CNC(=O)N2CCN(C(=O)c3ccoc3)CC2)ccn1 +Cc1ccc(OCC(=O)Nc2nnc3n2CCS3)cc1 +COc1ccc(C2c3c(oc4ccc(C)cc4c3=O)C(=O)N2C)cc1 +Cc1ccc(Br)cc1NC(=O)c1c(C)n[nH]c1N +CC(=O)c1ccc(NC(=O)C(C)CN(C)C(=O)OC(C)(C)C)cc1C +Cc1ccc(-c2ccc(C(=O)N3CCCC(C)C3)c(N)n2)cc1 +COc1ncccc1C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +COC(=O)C(NC(=O)Cc1ccc(Cl)cc1)c1ccccn1 +Cn1c(CCc2ccccc2N)nc2ccccc2c1=O +CC(C)C(NC(=O)c1cccc2nscc12)C(=O)N1CCCC1 +CC1CN(C2CCN(Cc3cc(F)c(F)cc3F)CC2)CCO1 +CC(C)NC(=O)NC(C(=O)N1CCc2ccccc21)C(C)C +COC(=O)N1CCN(C(=O)c2ccc(C)c(N3CCNC3=O)c2)CC1 +CC(C)NS(=O)(=O)Cc1ccc(CNC(=O)c2ccco2)cc1 +Cc1nc2sccc2c(=O)n1NC(=O)C1CCCC1 +Cc1ccc(C(O)CCCC(=O)NCc2ccncc2)c(C)c1 +Cc1cn2c(CC(=O)Nc3cccc(C)c3C)csc2n1 +O=S(=O)(NCc1ccccc1)NCc1nc(-c2ncccn2)no1 +O=C(CC1CC1)N1CCC2(CC1)CN(CCn1cccn1)C(=O)CO2 +C=CCNC(=O)c1ccc(OCCOC)c(Br)c1 +COc1cccc(OC)c1C(=O)NCCn1ncccc1=O +OCCNc1nc(-c2ccccc2)c2ccccc2n1 +Cn1c2c(c(=O)n(C)c1=O)C(c1cc(F)ccc1F)CC(=O)N2 +O=C(NCCn1nc(C(F)(F)F)cc1C1CC1)Nc1cccs1 +O=C(c1c(F)cccc1F)N(Cc1ccsc1)C1CC1 +O=C(NC1CCCC1)c1nc(-c2ccc3[nH]ccc3c2)no1 +CC(C)NC(=O)Cc1ccc(NC(=O)C(NC(N)=O)C(C)C)cc1 +COC(=O)c1cccc(NC(=O)NC(C2CC2)C2CC2)c1 +NC(=O)NCc1ccc(C(=O)OCc2nc3ccccc3[nH]2)cc1 +COc1ncccc1NC(=O)Cc1csc(N2CCCC2=O)n1 +CCC(C)N(C)C(=O)Nc1ccc(N(C)C(C)=O)cc1 +CC1=NC(=O)C(CCC(=O)Nc2cc(C)ccc2F)C(C)=N1 +O=c1[nH]nc(CN(Cc2cccc(O)c2)C2CCC(O)CC2)[nH]1 +Cc1csc(SCC(=O)N2CCc3ccccc3C2)n1 +O=C(CN1CCCC2(C1)OCCO2)Nc1nc(-c2ccco2)cs1 +O=C(Nc1cccc(-c2cn[nH]c2)c1)c1cc(-c2ccco2)[nH]n1 +COCC(O)CN(C)C(=O)C(C)(C)c1ccccc1 +CC1CCCC(NC(=O)CSc2nncs2)C1C +Cc1nsc(NC(=O)N2CCC(Cc3ccc(F)cc3)CC2)n1 +O=c1cnnc2sc(CCc3cccc(O)c3)nn12 +CCS(=O)(=O)N1CCc2nc(-c3ccccc3)nc(C)c2CC1 +CN(Cc1ccc(F)cc1)c1ccc2nnnn2n1 +CSc1ccc(C)c(C(=O)N2CCC(CO)CC2)c1 +Cc1c(Cl)cccc1NCc1ccccc1C(N)=O +Cc1oc(S(=O)(=O)N(C)C)cc1C(=O)Nc1ccc(Cl)cc1 +CC(C)C(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +CC(C)c1cc(C(=O)NCCNc2cnccn2)n[nH]1 +CNC(=O)c1ccc(NC(=O)N(C)C(C)c2ccccc2F)c(C)c1 +CCCn1c(C)nnc1SC(C)C(=O)NC1CCCC(C)C1C +CC(C)c1nc2ccc(NC(=O)c3ccncc3F)cc2s1 +Cc1noc(C)c1C(C)C(=O)N1CCCC1(C)C +CCCn1cc(C(=O)Cc2ccccc2Br)cn1 +CCOc1cc(CNc2cc(C)ccn2)ccc1O +CCOC(=O)c1ccc(NC(=O)NC(CO)c2ccccc2)cc1 +CSc1nnc(-c2ccccc2Br)n1N +Cc1nc(C(=O)Nc2c(C)nn(C)c2Oc2cccc(F)c2)cs1 +COCCNC(=O)C1CCN(c2ccc(Cl)cc2)C1=O +Cc1nccn1CCCNC(=O)c1nc(-c2ccccc2)no1 +CC(C)N(C)C(=O)CCNS(=O)(=O)c1ccccc1F +CCc1ccccc1NC(=O)CN1C(=O)CCCc2sccc21 +CCOc1ccc(NC(=O)Cn2nc(C)c(Cl)c2C)c(C)c1 +CCN1C(=O)C(Cc2ccccc2C)Oc2cc(N)ccc21 +COCc1oc(-c2cc3ccccc3o2)cc1CC#N +COc1cccc(NC(=O)C(C)n2c(=O)[nH]c3ccccc3c2=O)c1 +Cc1ccc(C)c2c1OCCC(CN1CCOCC1)C2=O +CCCN(CCO)C(=O)NCc1cc(C#N)ccc1F +Cc1cc(N2CCC3(CC2)Nc2ccccc2NC3=O)n2nccc2n1 +C#CCOC(=O)c1cc(CC=C)c(OC)c(OC)c1 +CC(=O)c1ccc(NC(=O)C2(C#N)CCCC2)cc1C +CCc1ccc(NC(=O)C(C)NC(=O)c2ccccc2)cc1 +CCCn1cnc2c1c(=O)n(C1CC1)c(=O)n2-c1cccc(F)c1 +COCC(=O)Nc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 +Cc1ccc(C2NCCc3c(O)ccc(F)c32)cn1 +O=C(Cn1cnc(C2CCC2)cc1=O)c1ccc(Br)cc1 +CS(=O)(=O)NCCCNC(=O)c1ccc2c(c1)OCO2 +CNC(=O)COC(=O)c1c(-c2ccccc2)noc1C +CC(C)NC(=O)NCC(=O)N1CCc2cnc(N(C)C)nc2C1 +Cc1cc(C(=O)Nc2ccc3ccccc3n2)c(C)n1C1CC1 +CC1(C)CN(C(=O)Cn2ccc3ccc(Cl)cc32)CCO1 +CC(=O)c1cccc(OCC(=O)N2CCN(c3ccccc3)CC2)c1 +COC(=O)CSc1nnc(-c2cccc(Cl)c2)n1C +CC(C)c1ncc(CN2CCOC3CCCCC32)s1 +O=C(Cc1ccc[nH]1)Nc1nc(-c2ccc(-n3cccn3)cc2)cs1 +CCOC1CCCN(C(=O)CN(C)c2ccc(C#N)cn2)C1 +CCC(CCNC(=O)c1cc(F)ccc1O)N1CCCC1=O +Cc1nc(CC(=O)N(C)c2ccc(Br)cc2C)cs1 +CNC(=O)c1ccccc1NC(=O)c1[nH]nc(C)c1Br +O=C(Cc1ccc[nH]1)NC1CCC(c2ccccc2)CC1 +CCOc1c(Cl)cc(CNC(=O)N2CCOCC2C)cc1OC +Cc1cc(C)n(CC2CCN(S(=O)(=O)c3ccccc3)CC2)n1 +C=C(C)COc1cccc(C(=O)N(C)Cc2ncccc2C)c1 +CCCOc1cccc(C(=O)Nc2ccc(N(C)C(C)=O)cc2)c1 +Cc1ocnc1CNC(=O)c1cnc2ccccn12 +O=C(CNC(=O)NC1CCCC1)Nc1ccc(Cl)cc1 +CN(c1ccccc1)c1ncnc(Oc2cccnc2)c1N +CC(O)c1cccc(S(=O)(=O)Nc2ccncc2)c1 +CCN(CC)C(=O)NC(c1nnc2n1CCC2)C(C)C +CN(C)c1nnnn1-c1ccc(Oc2ccccc2)cc1 +NC(=O)c1ccccc1NC(=O)NC12CC3CC(CC(C3)C1)C2 +CC1=C(C(=O)OCc2ccccc2)C(c2cccnc2)n2nnnc2N1 +O=C(Nc1ccc2c(c1)OCO2)c1ccc(Cn2cccn2)cc1 +N#Cc1ccc(NC(=O)c2ccccc2C(F)(F)F)nc1 +O=C(CNC(=O)C1CCCC1)NCC1CC=CCC1 +Cc1cc(C(=O)NCCOC(N)=O)c(C)cc1Br +CC(C)CCNC(=O)C1CCCN1C(=O)Nc1cccc(F)c1 +O=C(NCc1nnc(-c2ccc(Cl)cc2)o1)c1ccc(F)cc1F +Cn1ccc(NC(=O)Cn2[nH]c(=O)c3ccccc3c2=O)n1 +CCS(=O)(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +COc1ccc(C(=O)CNS(=O)(=O)N(C)C)cc1Cl +CCS(=O)(=O)c1ccc(NCC(=O)NC2CCCCC2)cc1 +Cc1ccc(C)c(C(=O)NCc2noc(C(C)C)n2)c1 +CN(CCO)S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +Cc1cc(C)c(C(=O)N(Cc2ccco2)CC2CCCO2)o1 +CC(Nc1ccccc1Br)c1nccs1 +COc1ccc(C(=O)Nc2ncccn2)c(OC)c1 +Cc1ccc(Cn2nnc(C(=O)NCc3ccco3)c2N)cc1 +CCn1c(C(=O)NCC(=O)NC2CC2)cc2ccccc21 +Cc1nc(C)n(CC(O)COCc2ccccc2)n1 +CCc1noc(CC)c1CC(=O)N1CCC(Cc2cnn(C)c2)C1 +CCOc1ccc(C(=O)CNC(=O)c2cccc(F)c2)cc1 +CCc1ccc(OCc2nnc3c(N)ccc(C)n23)cc1 +Nc1cccc(-c2csc(NC(=O)c3cccc(F)c3)n2)c1 +O=C(CCC(=O)c1ccccc1)Nc1ccccc1 +CCc1ccc(C2CC(=O)Nc3c2c(=O)n(C)c(=O)n3C)cc1 +Cc1cc(C)n(CC(C)CNC(=O)c2cc(C(N)=O)cs2)n1 +O=C(c1ccc2ccccc2c1)N1CCC(Oc2cccnc2)CC1 +Cc1cc(CC(=O)N(C)Cc2noc(C(C)C)n2)on1 +Cc1ccc(C(C)C)c(OCC(=O)NCC(=O)NC2CC2)c1 +O=C(Nc1ccc(C(=O)Nc2ccccc2O)cc1)c1ccc(=O)[nH]c1 +CC(OC(=O)c1ccc2ccccc2n1)c1nc2ccccc2c(=O)[nH]1 +CC(C)COc1cc(NCCc2c[nH]c3ccccc23)ncn1 +COc1ccc(C(=O)N2CCc3cc(F)ccc3C2)c(OC)c1 +CCc1nc(CNC(=O)NCc2ccc(-n3cccn3)nc2)cs1 +Cc1ccc(C(=O)CCNc2ccc(C(=O)c3ccncc3)cc2)o1 +COc1ccc(C(=O)OCC(=O)Nc2cccc(C)c2)cc1N +O=C(c1cnccn1)N1CC2CCCC2(COCc2ccccn2)C1 +CN(C)C(=O)N1CCN(c2nccc(C(F)(F)F)n2)CC1 +CC(C)NC(=O)C(C)OC(=O)Cn1ccc(N)n1 +CCCc1ccc(C(O)CCCC(=O)N(C)C)cc1 +OCCN(Cc1cccnc1)Cc1ccc(-c2cccc(F)c2)s1 +COCCCNC(=O)C1CC(=O)N(c2cc(Cl)cc(Cl)c2)C1 +C=CCNC(=O)N1CC=C(c2c[nH]c3ccc(OC)cc23)CC1 +CN(C(=O)Cc1ccc2c(c1)OCCO2)c1nc2ccccc2s1 +N#Cc1cccc(NC(=O)Cn2cnc3c(oc4ccccc43)c2=O)c1 +O=C(NCc1ccc(F)cc1)N(Cc1cccnc1)CC1CCCO1 +O=C(C1CC=CC1)N(Cc1cccnc1)Cc1ccco1 +CNC(=O)NCCC(=O)Nc1ccc(Br)cc1 +CCOCC(=O)OCc1nnc(-c2ccccc2Cl)o1 +CC(=O)c1cc(C)cc(CCNC(=O)OC(C)(C)C)n1 +CCC(=O)N1CCC2(C1)C(=O)N(C)c1ccccc12 +CCNC(=O)c1ccccc1SC(C)C(=O)OC +O=C(NCc1cc(F)ccc1F)c1ccc(-c2cscn2)cc1 +Cc1nc(-c2cccc(NC(=O)c3ccc(NC4CC4)nc3)c2)oc1C +CC(C)(C)C(O)c1ccc2c(c1)CN(S(C)(=O)=O)CC2 +CC(C)OC(=O)C(C)n1nc(C#N)cc1-c1ccccn1 +CC(=O)Nc1cccc(NC(=O)c2ccccc2-n2cccn2)c1C +CCOc1ccccc1-c1ccc(C#N)c(=O)n1CCOC +CC(=O)Nc1ccc2nc(NC(=O)c3nn(C)cc3N)sc2c1 +CCOc1ccccc1-c1nnc(SCCCO)o1 +CCN1CCc2nc(NCc3ccc(OC)c(OC)c3)sc2C1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)Cc1sccc1C +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)N=c1[nH]c2ccccc2[nH]1 +O=C1Nc2ccccc2C12CC(O)=Nc1[nH]ncc12 +O=C(CCCn1cnc2ccccc2c1=O)NC1CCCCC1 +Cc1cc(-c2nnn(-c3ccccc3)c2N)ccc1Cl +CCCn1c(-c2ccc(C)cc2C)ccc(N)c1=O +Nc1ccc(C(=O)OCCn2cccn2)c(Cl)c1 +O=C(CCn1cnnc1)N1CCCC(c2nc3ccccc3[nH]2)C1 +CCNC(=O)CCCC(=O)NCC1CCC(C)(C)CC1 +CCOc1ccc(C(=O)CCC(=O)OC)cc1Cl +CCCn1c(SCC(=O)Nc2nc3ccccc3s2)n[nH]c1=O +CC1(C)Cc2c(sc3ncn4nc(C(=O)NCCO)nc4c23)CO1 +COc1cccc(Cn2cc(NC(=O)C(C)C)cn2)c1 +CCc1nc2n(n1)CCCC2NC(=O)NCCCNC(=O)C1CCC1 +Cc1ccc(CNC(=O)N(C)Cc2ccccn2)s1 +CCOCCCNC(=O)c1cnc(N2CCOCC2)nc1C +COC1CCCN(C(=O)Nc2ccc(C)c(N3CCCC3=O)c2)C1 +CNC(=O)c1cccc(NC(=O)NC(C)CCCO)c1C +COc1ccc(NC(=O)NCc2nc(C)no2)cc1 +CC(=O)N(C)Cc1cccc(NC(=O)NCC(C)Cn2cccn2)c1 +CN(Cc1ccc(Oc2ccccc2)cc1)C(=O)Cn1cccnc1=O +Cc1nc(CNC(=O)c2cccn2Cc2ccccc2)c(C)s1 +CC(C)c1nc(CNCc2ccc(-n3ccnc3)nc2)cs1 +Cc1ccc(-c2nnc(Cn3cnc4ccccc4c3=O)o2)cc1 +CCCCN(CC)C(=O)c1ccc2onc(-c3csc(C)n3)c2c1 +CC(=O)Nc1cc(C(=O)NC2CCCC2)c2ccc(C)nc2c1 +Cc1ncc(CN(C)CCc2ccncc2)n1-c1ccccc1 +CCOC(=O)C1=C(CNC(C)(C)C)NC(=O)NC1 +NS(=O)(=O)c1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)o1 +COCC(O)CN(C)C(=O)CNC(=O)c1cc2ccccc2[nH]1 +O=C(NCCNC(=O)c1cc(F)ccc1F)c1ccccc1O +COCC(C)NC(=O)NC(C)COc1ccc(F)cc1F +COC(C)C(=O)Nc1ccc(N2CCOCC2)cn1 +Cc1cccc(NC(=O)CSc2nc(=O)n3cc(C)ccc3n2)c1 +Cn1nnnc1-c1cccc(C(=O)NCc2cccc(Cl)c2)c1 +COc1ccc(CCC(=O)N2CCCc3ccc(N)cc32)cc1 +CC(=O)Nc1ccccc1OCc1cc(-c2cccs2)on1 +CCn1cnc(-c2nc(C(=O)N3CCN(C)CC3)c3ccccn23)c1 +Cc1ccc(Cn2ccccc2=NC(=O)c2ccc(=O)[nH]c2)cc1 +Cc1nc(C)c(C(=O)NC2CCCc3[nH]c(=O)c(C(N)=O)cc32)s1 +CCCOc1ccccc1OCC(=O)c1cc(C)n(C)c1C +N#CCn1c(CSc2nnnn2C2CC2)nc2ccccc2c1=O +O=C(Cn1ccc(=O)c2cccc(F)c21)NCCc1ccccc1 +Cn1cc(CC(=O)Nc2ccc3c(c2)OCO3)c2ccccc21 +COc1cc(C(C)=O)ccc1OCC(O)Cn1nc(C)c(C)c1C +O=C1CCC(COC(=O)c2ccccc2COc2ccccc2)N1 +Cn1cc(NC(=O)C2CCC(F)(F)CC2)c(=O)n(C)c1=O +CCCCNC(=O)CNC(=O)c1cc(F)cc(F)c1 +CC(=O)N1CCCC(C(=O)NCC(O)c2ccc(C(C)C)cc2)C1 +CC(=O)Nc1ccccc1NC(=O)C(C)Oc1cccc(C)c1 +COC(=O)C1COc2ccc(-c3ccccc3)cc2C1=O +CCOC(=O)CSc1cc(N2CCCCC2)ncn1 +CS(=O)(=O)c1ccc(NC(=O)c2ccc(N)cc2)cc1 +CC(=O)NCCC(=O)NCc1nc(-c2cccs2)no1 +O=C(Nc1cc(Cl)ccn1)c1ccnc(OC2CCC2)c1 +COc1ccccc1N1CCN(C(=O)c2cc(C)no2)CC1 +CC(=O)c1ccc(NC(=O)CSc2nnc(C(C)(C)C)n2N)cc1 +O=C(Cc1ccc(F)cc1F)Nc1ccccc1C(=O)NC1CC1 +O=C(NCCNc1ccc(-n2cccn2)nn1)c1ccco1 +CCc1cccc(CC)c1NC(=O)NC1CCN(C(=O)C2CC2)CC1 +CCNC(=O)CCC(=O)c1ccc(OC)c(OC)c1 +COc1cc(C)ccc1OC(=O)Cn1ncc(=O)c2ccccc21 +CC(C)C(NC(=O)Cn1ccnc1)c1ccc2c(c1)OCCCO2 +CN(C(=O)Cn1nc2n(C)c3ccccc3n2c1=O)C1CCCCC1 +COc1ccc(NC(=O)C2CCCCN2S(C)(=O)=O)cc1 +Cc1noc(C2CCCN(C(=O)c3ccc(C(C)(C)C)cc3)C2)n1 +Cc1ccc2c(c1)CCCN2C(=O)C1CC(=O)N(C)C1 +CCSc1ccc(C(=O)n2ncc(C#N)c2N)cn1 +CCOc1cc(C#N)ccc1OCC(=O)NC(C)C(C)C +O=C(NCCCn1ccc2cccnc21)c1cc(=O)c2ccccc2o1 +CC(C)C(=O)Nc1ccc(OCC(=O)NC(C)C(C)C)cc1 +Cc1ccc(F)c2c1CCCN2C(=O)c1cccc(-n2cnnn2)c1 +O=C1C(NS(=O)(=O)c2cccs2)CCN1c1ccccc1F +Cc1ccc(NC(=O)COC(=O)CCc2c(C)nc(C)[nH]c2=O)cc1 +COc1cccc(C(N)=O)c1OCC(=O)Nc1cc(C)on1 +CCc1cccc(C)c1NCC(=O)c1ccc2c(c1)OCCO2 +CS(=O)(=O)NCCCNC(=O)C1COc2ccccc2O1 +COc1cccc(CNc2ncnc3c2cnn3C)c1 +CCN(CC(=O)OC)C(=O)c1ccc(F)cc1F +COc1ccc(NC(=O)c2cc(N)ccc2Cl)cc1 +CCOc1cc(CO)cc2c1OC(CC)C(=O)N2CCC(C)C +COC(=O)c1cccc(CSc2nnnn2C)c1 +CC(=O)Nc1ccc(NC(=O)c2cccc(C(N)=O)c2)cc1 +O=C(CCC1CCCCC1)NCC1(O)CCOCC1 +O=C(NC1CC1)N1CCN(c2ccc(F)cc2)CC1 +N#Cc1ccccc1NCc1ccccc1C(N)=O +CC(C)(NC(=O)c1cnc(C2CCCO2)s1)c1cccc(F)c1 +O=C(CCC1CCCC1)N1CC(c2nc(-c3ccco3)no2)C1 +CN(C)C(=O)Cc1ccccc1NCc1ccc(C#N)cc1 +COc1ccc(F)c(CN2CCCC(c3cc(=O)[nH]c(C)n3)C2)c1 +COC(=O)c1cnn(-c2cc(Oc3cccc(C)c3)nc(C)n2)c1C +CN(C)C(=O)CNc1cccc(OCc2ccccc2)c1 +C=CCc1cc(C(=O)NCC(C)C)cc(OC)c1OC +COc1ccnc2c1c(=O)n(CC(=O)N1CCOCC1)c(=O)n2C +CCc1cc(=O)[nH]c(NCc2ccc(OC)cc2)n1 +CCOc1ccc(OCCn2c(=O)oc3ccccc32)cc1 +O=C(c1ccc2c(c1)OCO2)N1CCCCC1c1ccccn1 +CC(C)NCC(=O)OCc1ccc2c(c1)NC(=O)C(C)O2 +CCCNC(=O)CC1CSc2nc(CCC)cc(=O)n21 +O=C1CCCc2cc(S(=O)(=O)NCCC3=CCCCC3)ccc2N1 +O=C(CCc1ccccc1)Nc1ccc2c(c1)COC2 +COc1ccc(C(=O)NCC(=O)Nc2ccnn2C(C)C)cc1 +Cc1ccc(NC(=O)NCCN2CCOCC2)cc1F +O=C(c1nnc2sc(-c3ccc(F)cc3)nn12)N1CCCCC1 +Cc1cc(C(=O)OCCN2CCOCC2)c2ccccc2n1 +NC(=O)C1CCN(C(=O)C(OCC(F)(F)F)c2ccccc2)CC1 +Cc1ccc(N2CCN(CCO)CC2)cc1Br +Cc1ccc2ncc(C(=O)NCC(C)(C)c3ccncc3)c(=O)n2c1 +CC1CCCN(C(=O)Nc2ccc(C(=O)N3CCCC3)cc2)C1CO +COc1cccc(C(=O)NCc2ccc(-n3ccnc3C)nc2)c1O +CCOc1cccc(C(=O)N(C)C2(C(=O)OC)CCCCC2)c1 +N#Cc1ccc(Oc2nnnn2-c2ccccc2)cc1 +O=S(=O)(c1ccccc1F)N1CCN(Cc2ccccc2)CC1 +O=C(NCCCOc1ccc(F)cc1)NCc1ccco1 +O=C(Cc1ccc(Cl)cc1)Nc1ccc2[nH]c(=O)sc2c1 +CCn1c(C)nnc1SCC(=O)Nc1cc(C)on1 +N#Cc1cccc(NC(=O)c2cccc(NC(=O)C3CCCC3)c2)c1 +Cc1cc(NC(=O)c2ccncc2)c2cc(C(=O)OC(C)C)ccc2n1 +CC1CN(CCCNC(=O)NCC(C)N2CCOCC2)CC(C)O1 +O=C(Cn1c(-c2ccccc2)nc2ccccc21)NCC1CCCO1 +Cc1cc(-c2cnc(NC(C)C)nc2-c2cccnc2C)on1 +O=C1CCCc2ccc(NCc3nc(C(F)(F)F)cc(=O)[nH]3)cc21 +CCOc1ccc(-c2nc(C)c(C(=O)N(CC)CCO)s2)cc1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCC1CC1C +CCOc1ccccc1C1Nc2ccccc2C(=O)N1CC +COc1cccc(C(=O)Nc2cnn(C)c2C(N)=O)c1OC +Cc1ccc(NC(=O)c2cc3c(s2)CCN3C(=O)C2CC2)nc1 +Cc1nc2cc(F)ccc2cc1C(=O)Nc1ccccc1-n1cncn1 +N#Cc1cc(F)ccc1CN(CCO)Cc1cccnc1 +CCOC(=O)Cc1cc(=O)[nH]c(Nc2nc3ccccc3o2)n1 +CCC(=O)C(C)OC(=O)c1cc2ccc(OC)cc2[nH]1 +CCCCCn1cnc2c1c(=O)[nH]c(=O)n2CCCC +Fc1ccc2c(c1)CCNC2c1cc(-c2cccs2)n[nH]1 +CC1CN(C2CCOC2=O)CCN1CC(O)c1ccccc1 +CCOc1ccccc1NC(=O)Nc1nnc(-c2cc(C)oc2C)o1 +Cc1nc2cc3c(cc2n1Cc1nccn1C)OCCO3 +CC(=O)N1CCc2cc(Nc3cc(C)nc(C)n3)ccc21 +COc1cccc(CCNC(=O)CSc2nncs2)c1 +O=C(NCc1nc2ccccc2s1)c1cccc2cccnc12 +COc1cccc(C2CCN2C(=O)c2cc(C(C)C)no2)c1 +CCc1nnc(NC(=O)CCc2ccccc2)s1 +OCCOc1ccc(Cl)cc1Br +Cc1nc(COc2ccccc2C(=O)NC2CCCC2)no1 +COc1ccc2c(C(=O)N(C)C)cc(-c3cnn(CCO)c3)nc2c1 +CCCCCOc1cccc(-c2cc(C(N)=O)nc(N)n2)c1 +Cc1ncsc1C(=O)NC(C)c1c(C)noc1C +CCCOc1cccc(NS(=O)(=O)c2ccc(C(N)=O)cc2)c1 +COc1ccc(Nc2nc(CSc3nnc(C)n3C)cs2)cc1 +COc1ccc(OCCN(C)C(=O)c2cccc3cccnc23)cc1 +O=C(Nc1ccc2c(c1)COC2)c1cc(Cl)c2c(c1)OCCO2 +CN(Cc1csc2ccccc12)C(=O)CNC(=O)CC(C)(C)C +O=C(Cn1ccc(=O)[nH]c1=O)NCCCOc1ccccc1F +CCNC(=O)c1ccc(Sc2ncc3ccccn23)nn1 +CCCNC(=O)CNC(=O)c1nc2nc(C)cc(C)n2n1 +O=S1(=O)N=C(NCCCN2CCOCC2)Nc2ccccc21 +CCOCC(=O)NCC1(c2ccc(OC)cc2)CCOCC1 +CCOc1c(Cl)cccc1NC(=O)CNC(=O)OC +O=C(NCCC(=O)N1CCCC1)c1ccnc(OC2CCC2)c1 +Cc1ccccc1CN1CCN(C(=O)c2nc(C)c(C)[nH]c2=O)CC1 +CC(C)(C)C(=O)N1CCCC(C(=O)Nc2ccc3c(c2)COC3)C1 +CN(CC(=O)Nc1ccc2c(c1)OCO2)S(C)(=O)=O +O=C(Nc1c(F)cc(F)cc1-c1ccccc1)c1cnccn1 +Cc1cccc(OCCCNC(=O)c2ccc(S(C)(=O)=O)cc2)c1 +CCn1nnc2cc(C(=O)NCCc3ccc(F)cc3)ccc21 +Cc1nnc(C(C)Nc2ccc(Br)cc2)o1 +COc1cccc(C2CCCN2C(=O)c2ccc3c(c2)OCO3)c1 +Cc1cc(C)c(C(=O)NCc2nccn2Cc2ccccc2)c(C)c1 +Cc1cc(Br)cc(C)c1OCC(=O)Nc1nccs1 +CN(C)C(=O)Cn1nc(-c2ccccc2)c2ccccc2c1=O +CCNC(=O)CNC(=O)NC1CCC(CC)CC1 +Cc1nn(C)c(C)c1C(=O)NC(C)c1ccccc1 +COCC(C)S(=O)(=O)NCc1ccc(Br)c(F)c1 +CCNc1ccnc(N2CCN(Cc3ccc4c(c3)OCO4)CC2)n1 +Cc1nnc(CNC(=O)c2ccc3oc(Cc4ccccc4)nc3c2)o1 +CCS(=O)(=O)NCCS(=O)(=O)NC1CCCC1(C)C +CSc1cccc(-c2cccc(OCC(N)=O)c2)c1 +Cc1ccc(F)cc1S(=O)(=O)NCc1ncn(C)n1 +COc1ccc(C(CC(=O)N2CCOCC2)NC(C)=O)cc1 +CCNC(=O)COc1ncnc2scc(-c3ccc(F)cc3)c12 +O=C(Cc1ccccc1)NCC(=O)Nc1ccc2c(c1)OCCCO2 +NC(=O)C1CCCN(C(=O)Cc2n[nH]c(=O)c3ccccc23)C1 +CCc1c(C(=O)Nc2ccc(C(C)=O)cc2)cnn1Cc1ccccc1 +COc1ccc(C(=O)c2cc(NC(C)=O)ccc2O)cc1 +CC(C)c1ccc(C#N)c(=O)n1Cc1ccc(C#N)cc1 +CN(C)C(=O)c1cc(NC(=O)N(C)CCc2ccc(F)cc2)ccn1 +CCNC(=O)CN(CC)C(=O)NC(C)c1ccc(C)c(F)c1 +N#CCCN(C(=O)CNc1cccc2ccccc12)c1ccccc1 +CCOC(=O)N1CCN(CC(=O)N(C)CC2CCCCC2)CC1 +CCCCc1nnc(SCC(=O)N2CCCC2)n1N +Cc1cccc2[nH]c(C3CCN(c4ncnc5[nH]ccc45)CC3)nc12 +CCSc1nnc(N)n1C(CC)C(=O)Nc1ccc(OC)cc1 +COC(=O)c1sc(NC(=O)c2cccnc2)nc1C +O=C(NCCc1ccc(Cl)cc1)Nc1cnn(-c2ncccn2)c1 +CC(=O)N1CCCc2cc(S(=O)(=O)Nc3ccn(C)n3)ccc21 +CC(C)(C)OC(=O)NCC1CCCN(C(=O)Nc2nncs2)C1 +CC(Cn1nnc2ccccc21)NC(=O)CCc1ccccc1 +CN(C(=O)CSc1nc(C2CC2)nc2ccccc12)C1=CCCC1 +CC(=O)Nc1cccc(-c2nnc(SCC(=O)N(C)C)n2C)c1 +CCOC(=O)CC1C(=O)NCCN1C(=O)c1ccccc1 +O=C(CCCNC(=O)NCCO)Nc1ccc(Cl)cc1 +CN(C)C(=O)c1ccc(NC(=O)CNc2cccc(C#N)c2)cc1 +CC(C(=O)Nc1nc(-c2cc(C(N)=O)co2)cs1)c1ccccc1 +CNS(=O)(=O)c1cccc(C(=O)NCc2csc(=O)[nH]2)c1 +c1ccc(-c2nnc(-c3cnc4onc(C5CC5)c4c3)o2)cc1 +CS(=O)(=O)Nc1ccc(NC2CCN(CC(F)F)CC2)cc1 +CCN(CCC(=O)OC)S(=O)(=O)c1ccc(F)c(Cl)c1 +O=C(NCCOCCO)c1csc(-c2cc3ccccc3[nH]2)n1 +NC(=O)C1CCN(C(=O)NCc2ccccc2OC(F)(F)F)C1 +Cn1nncc1CNc1cnn(Cc2ccc(Cl)cc2)c1 +Nc1nc(N)n2c(-c3ccccc3Cl)nnc2n1 +CC(C)CNS(=O)(=O)c1cnn(C2CCCCC2)c1N +CC(C)(C(=O)NCC(=O)NCCO)c1cccc(C(F)(F)F)c1 +Cc1cc2c(cc1F)CCNC2c1ccccc1C#N +CN(CCC(N)=O)C(=O)c1cc2c(-c3ccccc3)nn(C)c2s1 +Cc1ccc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)cc1 +Cc1cc(C)c(C(=O)N(C)CCN2CCOC2=O)c(C)c1 +Cc1cc(C(=O)NC(C)c2ccc(F)cc2Cl)on1 +Cc1nc(SC(C)c2ccccc2)[nH]c(=O)c1CC(=O)NC(C)C +O=C(OCCN1CCCC1=O)c1ccc(-c2ccccc2Cl)o1 +CCOC(=O)Cn1c(=O)c(C#N)cn(C2CC2)c1=O +COc1ncccc1C1NCCc2cccc(Cl)c21 +CNC(=O)c1ccc(Cl)c(NC(=O)NCc2cnn(C)c2)c1 +Cc1ccc2oc(C(=O)NCc3nonc3C)cc2c1 +Cc1cc(C)c(C(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(C)c1 +Cc1ccc(C)c(NC(=O)C(C)Sc2nccc(=O)[nH]2)c1 +COc1ccc(C(=O)NC2CCCC2C#N)cc1F +O=C(NCc1cccnc1)NC(C(F)(F)F)C(F)(F)F +O=C(Cc1csc(-c2ccc3c(c2)OCO3)n1)NCc1ccco1 +Cc1cc(C(=O)Nc2c(C)cccc2C)ccc1N(C)S(C)(=O)=O +CCOc1ccccc1CN1C(=O)C2(OCCO2)c2cccc(C)c21 +CCC1COCCN1C(=O)CCN(C)S(C)(=O)=O +CC(=O)Nc1cccc(NC(=O)CCc2ccco2)c1 +O=C(COc1ccccc1F)Nc1cnn(C2CCOC2)c1 +CC(NC(=O)C1CCCC1)C(=O)Nc1ccc(Cl)cn1 +CC(C)C(=O)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +CCNC(=O)c1ccc(CNC(=O)c2n[nH]c(=O)[nH]2)cc1 +CCCc1ncc(-c2nnc(NCC(C)C)s2)s1 +CCc1ccc(C(C)NC(=O)C(C)Nc2ccn(C)n2)cc1 +CCNC(=O)c1ccc(NC(=O)c2ccc(SC)cc2)c(C)c1 +COCCS(=O)(=O)N(Cc1ccccc1F)C1CC1 +CC(=O)c1ccc(OCc2n[nH]c(-c3ccncc3)n2)cc1 +COCc1ccc(C(=O)NCc2cccnc2-n2cncn2)o1 +COc1cccc(CN2CCN(C(=O)c3ccc(F)cc3)CC2)c1 +Cc1[nH]c(=NC(=O)C(C)C)ccc1Br +COCCNC(=O)CNc1ccccc1C(N)=O +CCn1c(CSc2nncn2C(C)C)nc2cc(F)ccc21 +COc1cc(Cl)c(C)cc1NC(=O)Cn1cnnc1C#N +CCC(=O)N1CCC(c2nc(C)c(-c3ccnc(C)n3)s2)CC1 +O=C(NC1CC1)N1CCC(c2nccs2)CC1 +COc1ccc(NC(=O)N(C)C(C)c2ccco2)cc1C +CCc1nc(CC(=O)N(Cc2ccc(C#N)cc2)C(C)C)cs1 +Cc1c(OCC(N)=O)ccc2c(=O)c(Cl)coc12 +COc1ccc(CN(C)Cc2cc(=O)c3cc(C)ccc3[nH]2)cc1 +CC(C)Cc1cc(C(=O)NCCNC(=O)c2ccc(Cl)cc2)[nH]n1 +Cc1cc(C)cc(N(C)C(=O)Cc2csc(N3CCNC3=O)n2)c1 +Cc1cc(NC(=O)C2CC2)sc1C(=O)Nc1c(C)n[nH]c1C +CC(C)CN1C(=O)CCC2CN(C(=O)c3ncoc3C3CC3)CCC21 +CC(C)N(C(=O)Cn1nc(-c2ccc(F)cc2)oc1=O)C1CCCC1 +CCSc1cc(C(=O)N(CC)Cc2ccccc2)ccn1 +O=C(NCCc1cccc(O)c1)c1ccc(Cn2cccn2)cc1 +CN(C)C(=O)c1ccc(NC(=O)c2ccccc2F)cc1 +CCC(=O)NCC(=O)N1CCCC1CC(=O)c1ccccc1 +COC(=O)C1=C(C)Nc2nc(SC)[nH]c(=O)c2C1c1cccnc1 +O=C(NCc1ccccn1)c1c[nH]c2ccc(Cl)cc2c1=O +CCN(CC(=O)OC)C(=O)c1cc(C(C)=O)c[nH]1 +O=C(Nc1cc(C(F)(F)F)ccc1O)c1ccccn1 +COc1cc(CCC(O)CO)cc(OC)c1OC +COc1ccc(C(=O)N2CCCC2C2=NC=CC2)cc1Br +CC(OC(=O)c1cccc(OCC(F)F)n1)C(C)(C)C#N +COc1ccc(Cc2nc3c([nH]2)CC(C)(C)CNC3=O)c(OC)c1 +O=C(Cc1cccs1)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +O=C(CCc1nc(-c2cccnc2)no1)Nc1ccc2c(c1)COC2 +CCn1c(N)nc2cc(C(=O)NCCc3nc(N)cc(=O)[nH]3)cnc21 +N#Cc1c2n(c(=O)n(CC(O)c3ccccc3)c1=O)CCCCC2 +CCCCCCNC(=O)c1onc(-c2cccnc2)c1N +CCOc1ccc(C(=O)C(C)NCc2ccccc2F)cc1N +CN(Cc1nccs1)C(=O)NCC1CN2CCCCC2CO1 +N#Cc1ccccc1Sc1ccccc1C(=O)NCC1CCCO1 +Cc1nn(C(C)C)c(C)c1NC(=O)C1CCC(=O)N1Cc1ccco1 +CCOC(=O)CC(c1cn(C)nc1C)c1oc(CO)cc(=O)c1O +CCc1noc(CC)c1CC(=O)Nc1cc(F)ccc1F +CCc1noc(C)c1C(=O)OCC1CC(=O)N(Cc2ccccc2)C1 +Cc1cc(C)n(CC(=O)N2CCC3(CC2)CN(C)C(=O)O3)c(=O)n1 +Cc1cccc(C(=O)N2CCC3(CCCN(CC(C)(C)C)C3=O)C2)n1 +O=C(Nc1ccnn1CCc1ccccc1)c1c[nH]c2cccc(F)c12 +CN(C)C(=O)c1ccc(Cn2c(=O)oc3cccnc32)cc1 +CC(C)C(=O)N1CCC(C)(C(=O)NCc2ccc3c(c2)OCO3)CC1 +CC(C)(CNC(=O)COc1ccc(C#N)cc1)N1CCOCC1 +CS(=O)(=O)c1ccc(C(=O)NCCc2cn3ccccc3n2)cc1 +COCC(NC(=O)c1cnn(-c2ccccc2Cl)c1C)C(N)=O +O=C(NCCC(O)C1CC1)NCc1cccs1 +COc1cc(Cl)c(C)cc1-n1cc(CO)nn1 +CCNC(=O)N(CC)Cc1nc(-c2cccc(C)c2)no1 +COc1cc2c(cc1OC)CN(C(=O)CC(C)C)CC2 +Cn1cnc(S(=O)(=O)N2CCC3NC(=O)CC32)c1 +COc1cc(C(=O)N2CC(C)OC(C)C2)ccc1C +CC1CCC(N(C)C(=O)c2ccc3ccccc3n2)CC1 +NC(=O)CCC(=O)c1ccc(C2CCCCC2)cc1 +Nc1cc(C(=O)NCc2ccccc2)c(Br)cc1F +COc1ccccc1C(C)NC(C)C(=O)N1CCc2ccccc21 +C#Cc1cccc(NC(=O)CNC(=O)NC(C)CC)c1 +Cc1cc(C(=O)N2CC(C(=O)N(C)c3ccccc3)C2)no1 +O=C(CC1C(=O)Nc2ncnn21)Nc1cccc(Cl)c1 +C#CCN1CCN(C(=O)NC(C)CCOC)CC1 +COCCC(C)(C)C(=O)N1CCCC(COC)C1 +Cc1c(NC(=O)c2nc3ncccn3n2)cnn1C +CC(C)(C)NC(=O)CNC(CO)c1ccccc1 +CC(NC(=O)NCCc1ccc(-n2cccn2)cc1)c1ccccc1 +CC1CCC(Nc2ccc(S(C)(=O)=O)cc2S(C)(=O)=O)CC1 +Cc1cccc(OCCCC(=O)Nc2cccc(N)c2)c1C +CC(C)(CNC(=O)C1CCOc2ccccc21)c1ccncc1 +Cc1cccc(S(=O)(=O)NCc2ccccc2F)c1 +CCOC(=O)CC1NCCc2c(OC)cc(OC)cc21 +CCNC(=O)CNC(=O)c1cccc(S(C)(=O)=O)c1 +O=C(Nc1cccc(F)c1F)N1CCCC1CN1CCOCC1 +Cn1cc(C(=O)NCc2ccccn2)c(=O)c2cc(F)ccc21 +Cc1nnc(NC(=O)Cc2coc3ccc(C(C)(C)C)cc23)s1 +Cc1nccn1-c1ccc(NS(=O)(=O)Cc2ccccc2)cn1 +CCOC(=O)CN(C)C(=O)c1cccc(-n2cccn2)n1 +O=C(NCCOc1ccc2c(c1)CCC2)c1cc(=O)c2ccccc2[nH]1 +CCN(CCO)C(=O)c1cc(S(=O)(=O)NC(C)(C)C)ccc1C +O=C(CNC(=O)c1cccs1)Nc1nc(-c2ccccn2)cs1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccccc1-n1cccn1 +N#Cc1ccc(F)c(COC(=O)c2ccc(Cn3cncn3)cc2)c1 +COc1cccc(C(=O)NCc2cccc(C)c2)c1O +COc1ccccc1CC1CCN(C(=O)c2ccn(C)c(=O)c2)CC1 +C=CCOc1ccc(C(=O)N2CCC(C)CC2)cc1Br +CCC(C)C(=O)NCc1cc(OC)c(OC)cc1Br +C#CCN1CCN(C(=O)NCCCn2nc3n(c2=O)CCCC3)CC1 +Cc1nc(N(C)C)sc1CN1CC=C(c2cccs2)CC1 +CC1=C(C(=O)N2CCCCC2)C(c2cccc(F)c2)n2ncnc2N1 +CCN1C(=O)CCc2cc(NCc3ccnn3CC)ccc21 +Cc1ccc(F)c(NC(=O)CCc2cnn(C)c2)c1 +CCNC(=O)c1ccc(CNC(=O)N(C)CCc2ccccn2)cc1 +Cc1cnc(C(=O)NC2(c3ccc4c(c3)OCO4)CCCC2)cn1 +O=C1COc2cc(S(=O)(=O)N3CCOCC3)c(Cl)cc2N1 +Cc1noc2nc(C(C)C)cc(C(=O)NCC3CCCO3)c12 +CCCCn1ncc(-c2ccccc2Cl)c(N)c1=O +Cc1noc(NC(=O)c2ccc(C(F)(F)F)nc2C)n1 +Cc1cccc(NC(=O)Nc2cccc(CNC(=O)c3ccc[nH]3)c2)c1 +COc1ccc(N(C(=O)c2ccc(=O)n(C)c2)C(C)C)cc1F +CC1Cc2c(NC(=O)c3ccccc3)nn(C)c2NC1=O +Nc1ncc(Br)cc1C(=O)NCc1cn[nH]c1 +Cc1cc(C)n(CCCNC(=O)c2c[nH]nc2-c2ccc(F)cc2)n1 +O=C(CCc1nnc2ccc(N3CCOCC3)nn12)N1CCOCC1 +Cc1noc(C(C)C)c1C(=O)NCCCn1nc2ccccn2c1=O +NC(=O)C1CCN(C(=O)CCc2cccc(Br)c2)C1 +CC(C)CNC(=O)N1CCCC(C(=O)NC2CCN(C)C2=O)C1 +Cc1ccc(NC(=O)NCc2ccc(-n3ccnc3)nc2)cc1Cl +Cc1cc(OCCCC(=O)NCc2ccccn2)ccc1Cl +CCc1ccc(NC(=O)Cn2c(N)nnc2SC)cc1 +Cc1ccc(C(=O)Nn2c(C)nc3ccccc3c2=O)cc1C +O=C(CNC(=O)c1ccc2nc(-n3cccc3)sc2c1)NC1CC1 +O=C(Nc1ccc(-n2ccnc2)nc1)c1ccc2ccccc2c1 +N#CCCN1CCN(S(=O)(=O)c2cccc(F)c2)CC1 +CC1(NC(=O)c2ccc(-n3cnc4ccccc43)nc2)CCOCC1 +CC(C)CCC(=O)N(C)CC(=O)N1CCOCC1 +COc1cccc(C(=O)CCC(=O)N2CCCC2)c1 +COc1ccc2oc(=O)c(C(=O)NCC3CCCO3)cc2c1 +Cc1cc(C)n2nc(CC(=O)Oc3ccc(C(C)C)c(C)c3)nc2n1 +COc1cc(N2CCC3OCCN(CC4CC4)C3CC2)ncn1 +CC(=O)NCCNC(C)C(=O)c1ccc2c(c1)CCN2 +Cc1ccc(NC(=O)COC(=O)CCc2ccco2)cc1 +CN(Cc1ccncc1)C(=O)Nc1cc(F)ccc1Cl +CCCCn1nc(C(=O)N2CCC(C(N)=O)C2)c2ccccc2c1=O +OCc1cccn2cc(-c3ccc4c(c3)CCCC4)nc12 +COC(=O)c1cccc(OCC(=O)NCc2cccc(Cl)c2)c1 +COc1c(C)cnc(CNC(=O)NCC(C)CC(C)O)c1C +COc1ccc(N)cc1CN1CCN(c2ccccc2)CC1 +COc1cc(CNC(=O)c2cnn[nH]2)cc(OC)c1O +CCOC(=O)c1ccsc1NC(=O)c1c(F)cccc1F +CC(=O)NC(C)(C)c1noc(Cc2c[nH]c3cc(F)ccc23)n1 +CN(C)C(=O)c1ccc(Cl)c(NC(=O)NCCC2=CCCCC2)c1 +O=C(NC1CCCCC1)NS(=O)(=O)c1ccccc1 +O=C(CCSc1ccc2c(c1)OCCO2)Nc1nccs1 +CC(=O)N(C)CC(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1 +CCc1ccc(C(=O)NC(C#N)c2ccccc2)s1 +CC(C)(CNC(=O)Nc1ccccc1OC(F)F)c1ccncc1 +O=C1Cc2cc(C(O)COc3ccccc3)cc(Cl)c2N1 +COC(=O)c1csc(NC(=O)c2cc(F)cc3[nH]cnc23)c1 +O=C(Nc1cc(F)c(F)cc1F)c1ccc(=O)[nH]c1 +Cn1c(=O)[nH]c(=O)c2c1ncn2CC(=O)c1ccccc1 +Cc1cc(S(=O)(=O)Nc2cc(F)ccc2C)c(C)s1 +CCCC(O)CNC(=O)NCC1CN2CCCCC2CO1 +NC(=O)C1(CNC(=O)C2CCCC(C(F)(F)F)C2)CCOCC1 +CCc1ccccc1CNC(=O)N(C)Cc1ccccn1 +COc1nccnc1N1CCC(NC(=O)CCn2nc(C)cc2C)C1 +CCCn1c(C)cc(C(=O)Cc2nc3scc(C)c3c(=O)[nH]2)c1C +COC(=O)c1c(C)[nH]c(C(=O)Cn2cc(Br)cn2)c1C +c1nc(N2CCOCC2)ncc1CNCC1CN2CCCCC2CO1 +Cc1ccc(-c2ccnc(NCC(O)c3ccc(O)cc3)n2)c(C)n1 +CN(Cc1ccc(-n2cccn2)cc1)C(=O)c1ccc2occc2c1 +Cc1cc(C(O)c2ccccc2Cl)cc2c1NC(=O)CC2 +O=C(Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1)C1CCCO1 +CS(=O)(=O)c1ccc(NC(=O)CCc2cccs2)cc1Cl +CCCNC(=O)CSc1nnc(-c2ccccc2)n1N +CCOC(=O)CSc1nc(-c2ccccc2)n[nH]1 +Cc1cc(C(=O)NCCc2cc(=O)[nH]cn2)c(=O)[nH]c1C +NC(=O)CSc1nc2cc(-c3ccccc3)sc2c(=O)n1N +O=C(Nc1ccccc1OCc1cscn1)C1CC2CCC1O2 +COc1ccccc1NC1C(=O)Nc2ccc(C)cc21 +COc1cc2c(cc1F)CCNC2c1cnccn1 +CC(C)c1nc2oc3ccccc3c(=O)c2c(=O)n1Cc1ccco1 +Cc1cc(NC(=O)CNc2ccccc2Cl)n(C)n1 +Cc1ccsc1CNC(=O)c1ccc(C#CC(C)(C)O)o1 +Nc1n[nH]cc1S(=O)(=O)Nc1ccccc1Cl +c1ccc(-c2nnn(CCc3ccccn3)n2)cc1 +Cc1ccc(C(=O)NCc2noc(C(C)C)n2)cc1 +Cc1nc(S(=O)(=O)Cc2ccccn2)n(CC(C)C)c1C +O=C(Nc1cccc(NC(=O)c2cccs2)c1)c1cnccn1 +CS(=O)(=O)N1CCN(C(=O)Cn2c(=O)[nH]c3ccccc32)CC1 +CC(=O)N(C)c1ccc(NC(=O)CCSc2ccccn2)cc1 +CC(C)C(=O)NCC1CCN(c2ccc(F)cc2)C1 +O=C(Cc1ccc(F)cc1)Nc1cccc(OCC2CCCO2)c1 +CNC(=O)c1ccc(-c2cccc(-n3cccn3)c2)s1 +CCSc1cc(C(=O)Nc2ccc(Cl)cc2C(=O)NC)ccn1 +COc1ccccc1NC(=O)c1nnn(-c2ccc(C)cc2)c1C +CCc1nc(C)sc1CNC(=O)C(c1ccccc1F)N(C)C +O=C(COC(=O)c1ccc2ccccc2c1O)NC1CC1 +CC(C)(C)OC(=O)Nc1ccc2c(c1)NCCO2 +CC(C)c1noc(CCCc2nc(-c3ccc(C#N)cn3)no2)n1 +CCNC(=O)c1nc(-c2ccccc2)n(-c2ccc(OC)cc2)n1 +Brc1cnn2cc(-c3cnoc3)cnc12 +CC1Cc2ccccc2N1CC(=O)N1CCN(Cc2ccccc2)CC1 +O=C(CC1OC(=O)c2ccccc21)Nc1nc2ccccc2[nH]1 +COC(=O)N(C)CC(=O)Nc1ccc2c3c(cccc13)CC2 +CC(NC(=O)Cc1ccc2c(c1)CCCC2)c1ccccn1 +O=C1CCc2cc(C(=O)Nc3ccccc3N3CCCC3)ccc2N1 +CC(=O)Nc1ccc(Cl)c(C(=O)NCC2CCCO2)c1 +Cc1n[nH]cc1CN1CCOC(c2ccc(F)c(Cl)c2)C1 +CC(CCc1ccccc1F)C(=O)N1CCCC1CS(N)(=O)=O +CCCN(Cc1ccc(C#N)cc1)CC(O)c1ccc(F)c(F)c1 +O=C(c1ccncn1)N1CCCC2(C=Cc3ccccc3O2)CC1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccccc1F +Cc1ccc(O)c(NS(=O)(=O)c2cccc(C#N)c2)c1 +Cc1ccsc1C(=O)NCC(c1cccc(F)c1)N1CCOCC1 +CCOC(=O)C1=C(C)OC(N)=C(C(=O)OC)C1c1ccc(OC)cc1 +CCOCCC(=O)N1CC(C)CN(C)c2ccccc21 +CCCCOc1ccc(-c2ccc(OC)nn2)cn1 +COc1ccc(-c2cn3cccc(N)c3n2)cc1Cl +Cc1c(C(=O)OCC(=O)NCC2CCCO2)sc2ccccc12 +CCOC(=O)c1c(SC(C)C(=O)OC)nc(=O)[nH]c1C +CCc1nc(CC(=O)NCCC(=O)N2CCCC2)cs1 +CCOc1ccccc1CNC(=O)Nc1ccccc1COC +CCOC(=O)C(C)(C)C(O)c1cc(C)c(O)c(C)c1 +CCC1CN(C(=O)NCCc2ccccc2F)CCO1 +CCC(C)NC(=O)N(CC)Cc1ccc2c(c1)OCO2 +Cc1cccc(NC(=O)c2cc3c(=O)n4ccccc4nc3s2)n1 +COc1ccc(C)cc1NC(=O)c1ccc(-c2noc(C)n2)cc1 +Cc1cc(C(=O)N(C)CCCn2cccn2)nc(N)n1 +O=C1OC2CC1N(C(=O)Nc1ccc3c(c1)OCO3)C2 +COCC(NC(=O)CSc1ccc(Cl)cc1)C(N)=O +Cc1nc2ncnn2c(C)c1CCC(=O)N1CCOCC1C1CC1 +Cc1c(C(=O)OCC(=O)N2CCCC2)cnn1-c1ccccn1 +COc1ccccc1CNC(=O)c1c(OC)cccc1OC +Cn1nnnc1SCCn1ccnc1-c1nc2ccccc2[nH]1 +CCc1ccc(C(=O)N2CCCCC2CO)s1 +CCc1nn(C)c2[nH]nc(NC(=O)C3(c4ccccc4)CC3)c12 +Cc1cc(C)nc(SCC(=O)NCC(C)(C)c2ccncc2)n1 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1ccc(OCC(F)(F)F)cc1 +CCCc1[nH]nc(C(=O)NC(C)COCC)c1N +CCOc1cc(-c2ncc(C#N)s2)ccc1OC +CC(Sc1ncccc1Br)C(=O)NCC(F)(F)F +Cc1ccc(OCCC(=O)N2CCNC(=O)CC2)cc1C +CCn1nc(C(=O)Nc2sccc2C(N)=O)cc1C +CC(C)(C)c1nnc(N2CCCN(c3ncccc3C#N)CC2)s1 +COCCN1CCN(C(=O)c2cc(=O)c3ccccc3o2)CC1=O +Cc1ccc(C)c(N(CC(=O)NC(C)(C)C)S(C)(=O)=O)c1 +CCc1nc(CC(=O)Nc2cccc(-n3cnnn3)c2)cs1 +O=S1(=O)CCCN1Cc1ccc(C#CCO)cc1 +COc1ccc(C2(CNC(=O)c3ccno3)CCCC2)cc1 +Nc1ccccc1NCCc1c[nH]c2ccccc12 +CCc1onc(C)c1NC(=O)NCc1ccccc1-n1ccnc1 +CC(C)N(C(=O)C(C)S(=O)(=O)c1nnc(N(C)C)s1)C(C)C +COc1ccc(C(N)C(=O)NCC(C)O)cc1C +CN(Cc1cccc(Cl)c1Cl)C(=O)c1n[nH]cc1N +Cc1ccc(C(=O)OCC(=O)Nc2ccc(F)cc2)cn1 +CNC(=O)COC(=O)CCc1ncc(-c2ccc(C)cc2)o1 +Cc1cc(C(=O)N2CCC(NS(C)(=O)=O)CC2)c(C)n1C(C)C +COc1ccnc(NC(=O)c2cccc(OCC(F)(F)F)n2)c1 +CCOC(=O)C(=C(NC1CC1)C(F)(F)F)C(C)C +Nc1cc(-n2cc(-c3ccncc3)nn2)ccc1Cl +CC(Sc1cc(Cl)ccc1Cl)C(=O)N1CCC(C(N)=O)C1 +O=C(Nc1ccccc1)C1CCCN(c2cccnn2)C1 +Cc1nn2cccnc2c1C(=O)NCCCCC(C)C +CCc1cccc(C)c1NC(=O)C(C)n1cc(CO)nn1 +CSc1ncccc1C(=O)NCC(=O)NC1CC1 +CC(=O)NCC(=O)NC(C#N)c1cccc(Cl)c1 +CCc1sc(C(N)c2ccc(C)c(C)c2)nc1C +COc1ccc(-c2ccc(C(=O)N3CCCC3)o2)c2cccnc12 +COC(=O)CSc1nncn1C(C)c1ccccc1 +CCC(=O)Nc1ccc(C)c(NCc2ccccc2C#N)c1 +CC(C)CCC(C)NC(=O)Cc1cn2ccccc2n1 +Cc1nc(SCC(=O)NCC2CCCO2)c(C(N)=O)c(C)c1C +CCn1cc(S(=O)(=O)Nc2ccc(-c3ccno3)cc2)cn1 +COC(=O)CCn1cnc2cc(C(=O)OC)ccc21 +CC(C)(C)NC(=O)C(c1ccco1)N(C(=O)c1csnn1)C1CC1 +COc1ncccc1C(=O)NCC(C)S(N)(=O)=O +CC(C)NC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OC(C)C2 +O=C(Nn1cnnc1)C1CCCN(c2cc(-n3cccn3)ncn2)C1 +CCOc1cccc(CNC(=O)c2ccc(-c3ccncc3)[nH]c2=O)c1 +N#Cc1ccc(Cl)c(NC(=O)c2ccc(F)cc2)c1 +CC(C)C(CC(=O)NCc1cccnc1)c1ccccc1 +Cc1nn(CC(=O)c2ccccc2)c(C)c1Br +CC(NC(=O)c1cc(=O)n(C)c2ccccc12)c1cccs1 +Cc1cc(C)nc(SCc2ccc(C(=O)N3CCCC3)o2)n1 +O=c1[nH]ncc(NCCc2c[nH]c3cc(F)ccc23)c1Cl +CC1CC(Sc2nnc(-c3ccc(C(C)(C)C)cc3)n2N)C(=O)O1 +CNC(=O)COc1cccc(Oc2cccc(F)c2C#N)c1 +CN1CC(NC(=O)c2ccc(OCC3CC3)nc2)CCC1=O +Cc1cc2ncc(CNCCc3ccsc3)cn2n1 +COC1CCN(Cc2nccs2)C1Cc1ccccc1 +Cc1ccc(CC(=O)N2CCC(C(N)=O)c3ccccc32)s1 +CCCNC(=O)CS(=O)(=O)c1ccc2ccccc2c1 +COC(=O)C(O)(CC(=O)c1ccc(OC)cc1)C(F)(F)F +COc1cc2c(cc1CNC(=O)c1ccncc1F)OC(C)C2 +O=C(CSc1nncs1)NCCc1c[nH]c2ccccc12 +CCCS(=O)(=O)N(C)C1CCN(c2ccc(F)cc2)CC1 +CC(C)n1c(NCCCO)nc2c1c(=O)n(C)c(=O)n2C +COc1ccccc1NC(=O)c1cccnc1N1CCOCC1 +CSc1ccc(OC(C)C(=O)N(C)Cc2ccc(C)o2)cc1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)NCC(C)c1ccsc1 +Cc1ccc(OCc2occc2-c2nc(C3CCOC3)no2)cc1 +COCCCCn1nc(-c2ccc(C)s2)ccc1=O +CCC(CO)Nc1ncnc2sc(C(=O)OC)c(C)c12 +COc1ccc(COC(=O)CNC(=O)C(C)(C)C)cc1 +Cc1cc2ncn(CC(O)CN(C)CC(C)C#N)c2cc1C +C#CCN1CCC(C(=O)Nc2cc(F)cc(F)c2)CC1 +Cc1cc(F)ccc1NS(=O)(=O)c1ccc(-n2cccn2)cc1 +O=C(NC1(c2ccccc2Cl)CC1)c1cc(=O)[nH]c2ccccc12 +Cc1ccc(C(C)NC(=O)Cc2c(C)nc3cc(=O)[nH]n3c2C)s1 +COc1cc(CNC(=O)c2ccc(N)cc2)ccn1 +COc1ccc(CNC(=O)c2cc(F)c(F)cc2Cl)cc1OC +Cc1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)cc1F +COCCn1cnnc1SCc1cccc(C#N)c1 +Cn1cc(NC(=O)Nc2ccc(NC(=O)C3CC3)cc2)cn1 +CCc1nc2c(NC(=O)c3ccccc3OC)cccn2n1 +CCC1CCCCN1C(=O)c1onc(-c2ccncc2)c1N +Cc1nn(C)cc1C(=O)NCc1c(C)nn(C)c1C +CC(=O)NC1CCCN(C(=O)Cc2coc3cc(C)ccc23)C1 +COC(=O)CCNC(=O)C(C)c1ccc2cc(OC)ccc2c1 +Cc1cc(C(=O)OC(C)C(=O)Nc2cccc3ccccc23)on1 +COc1cccc(C(=O)NCc2nc(C(=O)NC3CC3)cs2)c1 +Cn1ccc(-c2nnc(NC(=O)NCCc3ccccc3)o2)n1 +CC(CNC(=O)NC1(C)Cc2ccccc2C1)N1CCOCC1C +Cc1cc(C)n(-c2nc(-c3cccs3)cs2)n1 +C=CCNC(=O)CN(c1ccc(CC)cc1)S(C)(=O)=O +Cc1ccccc1CNS(=O)(=O)CCc1ccccc1 +COc1cc(-c2nc(Cc3ccc4c(c3)OCO4)no2)ccc1O +CCCNC(=O)c1cccc(NC(=O)Cn2ccc(=O)[nH]c2=O)c1 +COC1CCN(C(=O)C(C)N2CCN(c3ccc(F)cc3)CC2)CC1 +COc1cc(CNC(=O)c2cc3ccccn3c2)cc(OC)c1OC +Cc1nnc(-c2csc(S(=O)(=O)N3CCCCCC3)c2)o1 +CCOC(=O)CN(CC)c1cnc2ccccc2n1 +CN(CC(=O)N1CCSc2ccccc21)c1ccccc1 +COc1ccc(NC(=O)c2cc(Br)ccc2F)cn1 +CCc1nn(CC(=O)NCCCOC)c(=O)c2cc3occc3n12 +NC(c1nnco1)c1ccc(F)cc1C(F)(F)F +Cc1nc2ccccn2c1C(=O)Nc1ccc2c(C)c(C)c(=O)[nH]c2c1 +CCNS(=O)(=O)c1cc(C#CCCO)ccc1OC +Cc1ccc(C)c(C(=O)C(C)Sc2nnc(CCC(N)=O)n2C)c1 +N#Cc1c(F)cccc1NCCc1ccc(S(N)(=O)=O)cc1 +CCCN(CC(=O)Nc1ccccc1C)C(=O)Cn1cnnn1 +Cc1sc2nc(C(C)Sc3nnc(C)n3N)[nH]c(=O)c2c1C +O=C(CCSc1ccc2c(c1)OCCCO2)Nc1ccc(F)cc1 +CC(=O)c1ccccc1C(=O)N1CC(C)(C)C1(C)C +CC(Oc1ccccc1)C(=O)C(C#N)c1nc(-c2ccccc2)cs1 +CC(C)OC(=O)Cn1cc(CO)c2cc(F)ccc21 +CCn1nccc1CN(C)C(=O)NC1CCCCC1 +CCS(=O)(=O)NCc1ccc(OC2CCCC2)cc1 +O=c1[nH]nc(SCc2cn3ccsc3n2)n1CC1CCCO1 +Cc1ccc(F)c(S(=O)(=O)Oc2cccc(CC(N)=O)c2)c1 +CCc1ccc(C2CCCN2C(=O)C(C)NC(N)=O)o1 +COc1ccccc1OC(=O)COc1ccc(Br)cc1 +CC1CCC(C(=O)NCC(C)(C)c2ccncc2)O1 +CC1CC(Sc2n[nH]c(=O)n2Cc2ccccc2)C(=O)O1 +CCNS(=O)(=O)c1ccccc1Br +O=C(Cc1ccc(Cl)c(Cl)c1)N1CCC(O)CC1 +Cc1ccc(-c2csc(NC(=O)Cc3cccc(F)c3)n2)o1 +CCNC(=O)CCCc1nc(-c2cccc(Cl)c2)no1 +N#Cc1ccc(NC(=O)NCCCOCC2CC2)cc1Cl +Nc1ccc(S(=O)(=O)Nc2cccc3ncccc23)cc1 +CC(CO)(CO)NC(=O)C1CCC(=O)N(CCc2ccccn2)C1 +CCCCNC(=O)c1cnc(N2CCCC2)nc1N +Cc1ccc(SCCCN(C)C(=O)CN2CCOC2=O)cc1 +C=CCNC(=O)C(C#N)c1nc2ccccc2nc1N1CCCCCC1 +Cc1cccc(N2CCN(C(=O)C3CC3c3cnn(C)c3)CC2)c1 +Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1CCC#N +COc1ccc(S(=O)(=O)c2cnc3ccccc3n2)cc1 +CC(C)n1nccc1NC(=O)N(Cc1ccco1)CC1CCCO1 +CC(=O)NCC(=O)NCC(=O)N1CCc2cc(F)ccc2C1 +N#Cc1ccccc1NC(=O)c1scnc1C1CC1 +CC(C)COc1cncc(N2CCC(CCO)C2)n1 +CCOC1(OCC)N=C(N)C2(C#N)C(c3ccccc3F)C12C#N +O=C(Cn1cncn1)NC(c1ccc(F)cc1)C1CCCO1 +COc1ccc(CCNC(=O)c2ccn(-c3ccc(F)cc3)n2)cc1 +Cc1ccnc(NC(=O)c2cc(C3CC3)nn2-c2ccccc2)c1 +Cn1c(=O)oc2cc(NC(=O)NCCc3ccc(F)cc3F)ccc21 +Cc1nnc(CN2CCCC(c3noc(C4CC4)n3)C2)o1 +O=C(Nc1ccc(F)c(F)c1)c1ccc(NC(=O)C2CC2)cc1 +CCCNC(=O)CCn1c(N2CCCC2)nc2ccsc2c1=O +CCC(CC)C(=O)Nc1cc(S(C)(=O)=O)ccc1Cl +Cc1nn(C)c(-c2cc(Br)cs2)c1N +O=S1(=O)CCCN1c1cc(Cl)ccc1Cl +Cc1ccc(O)c(-c2cc(C(=O)Nc3c(C)cccc3C)[nH]n2)c1 +Cc1cccc(NC(=O)NC2CC(=O)N(c3ccc(F)cc3)C2)c1C +CN(CCC#N)CC(=O)Nc1ccnn1C1CCCC1 +CC(C)c1ccc(OCCNC(=O)C2CCCn3ccnc32)cc1 +Cc1nc(C)c(NC(=O)c2cnc3c(c2)c(C)nn3C)s1 +Cc1nnc2ccc3nnc(-c4cc(Cl)ccc4OC(C)C)n3n12 +COc1cc(C#N)ccc1OCc1cccc(C)c1 +Cc1cc(C)c(NC(=O)Cn2ccnc2)c(Cl)c1 +O=C(c1cccc(C#CCO)c1)N(CCO)C1CC1 +CC(C)NC(=O)COC(=O)c1ccc(Br)cc1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cccc(Cl)c1 +COc1c(O)c(Cl)cc2c1C(c1cccnc1)NCC2 +Cc1noc(C)c1CCC(=O)OC(C)C(=O)Nc1ccc(C#N)cc1 +CCC(=O)N1CCCCC1C(=O)Nc1nccs1 +O=S(=O)(C1CC1)N1CCC2(CC(n3cnnc3)CO2)C1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccccc2F)c1C +Cn1ccnc1C(NC(=O)c1ccc2[nH]nnc2c1)c1ccccc1 +O=C(Cn1nnc(-c2cccs2)n1)N1CCc2ccccc2C1 +CC(C)C(NC(=O)C1CCCO1)C(=O)N1CCNCC1 +CC(C)Cn1ncc(C(=O)OCc2cnn(C)c2)c1C1CC1 +O=C(COc1ccc(Cl)cc1)Nc1ncccc1Cl +CC1CCCN(C(=O)CSc2n[nH]c(=O)n2CC2CCCO2)C1 +CN(C(=O)CSc1ccc(C#N)cc1)c1ccc(Cl)cn1 +CCOC(=O)c1ccc(-n2c(C)nc3cnccc32)cc1 +CCNC(=O)CN(C)C(=O)C(C)NC(=O)OC(C)(C)C +CN(C(=O)C1CC=CC1)C1CCCN(c2ccccc2)C1 +CCn1cc(C(=O)NCCS(=O)(=O)N2CCc3ccccc32)cn1 +CCCN(Cc1ccccc1)C(=O)C1CCCn2ccnc21 +Cc1nnn(CCNC(=O)CCC=Cc2ccccc2)n1 +Cc1ccc(CC(C)NC(=O)Nc2ccn(C)n2)c(C)c1 +COc1ccc(CSc2nnc(-c3ccc[nH]3)o2)cc1F +NC1=NC(=O)C(Cc2ccco2)(c2ccc(F)cc2)N1 +CCOC(=O)c1cccnc1NCc1c[nH]nc1C +CCOc1ccc2cc(CNc3ccc4[nH]ncc4c3)c(=O)[nH]c2c1 +COC1CCN(C(=O)Cc2ccco2)CC1Cc1ccccc1 +CCCNC(=O)c1ccc(-c2ccc(F)c(F)c2)nc1N +CCc1nnc(CSc2nccn2C2CC2)o1 +COc1ccc(C(O)CCC(=O)N2CCCC2)cc1C +O=C(Cc1n[nH]c(=O)c2ccccc12)NCc1ccc(F)cc1 +Cc1cccc(-c2ncc3c(Br)ccn3n2)n1 +O=S(=O)(NC(c1ccccc1)c1ccc(F)cc1)c1cccnc1 +Cc1nc(C(C)(C)NC(=O)C2CC3CCC2C3)sc1C +OCC1(c2ccccc2)CCCN1c1ccccc1 +CN(Cc1cccc(F)c1)C(=O)CNC(=O)c1cc(F)cc(F)c1 +CC(O)CNC(=O)CN1c2cccc3cccc(c23)S1(=O)=O +CC(C)COc1ncccc1C(=O)N1CCOCC1CC(C)C +Cc1[nH]nc2ccc(C(=O)OC(C)(C)C(C)(C)O)cc12 +O=C(c1ccncn1)N1CCC2(CC(OCC3CCOCC3)CO2)C1 +CCN(CC)C(=O)c1cc(C)nc(N2CCCCC2)n1 +Fc1cc2ncnc(Oc3ccc4ncccc4c3)c2cc1F +CCOC(=O)c1cc(NC(=O)c2ccc3[nH]cnc3c2)c[nH]1 +CCN(CCC#N)C(=O)CNc1ccccc1C(F)(F)F +O=C(NCCc1cc(F)cc2c1OCOC2)N1CCCC(CO)C1 +CC(C)C(=O)NC1CCCN(C(=O)c2ccc(N(C)C)cc2)C1 +Cc1ccccc1-c1cc(NS(=O)(=O)c2cccnc2)n(C)n1 +CCc1nc(-c2ccc(NC(=O)NCc3ccco3)cc2)no1 +Cc1cc(C(F)(F)F)nc(C2CCCN(C(=O)CO)C2)n1 +CCn1cc(-c2ccc(OC)cc2)cc1C(=O)NC(C)c1ccccn1 +COC1CCCN(C(=O)Nc2cccc(C)c2C)C1 +O=C(Cn1c2ccccc2c2ccccc21)N1CCn2cnnc2C1 +O=C(Nc1ccc(Oc2cccnc2)nc1)NC1CCCC1 +Cc1ccc(C=CCC(=O)N2CCN(C(=O)c3ccncc3)CC2)cc1 +COc1ccc(NC(=O)NC2(C)Cc3ccccc3C2)cc1OC +Cc1nc2sc3c(c2c(=O)n1Nc1ccc(O)cc1)CCCC3 +CC(C)C(c1nnnn1CCc1ccccc1)N1CCOCC1 +CCNS(=O)(=O)c1cc(Cl)ccc1Cl +Cc1nc2ccc(NC(=O)Cn3cnc4c(C)cccc4c3=O)cc2o1 +Cc1noc(CCC(=O)Nc2ccc(Sc3nccn3C)cc2)n1 +COC(=O)c1cc(-c2ccccc2)nc2c1cnn2C +CCCCc1ccc(NC(=O)N2CCOCC2)cc1 +CSc1nnc(CNC(=O)OC(C)(C)C)n1-c1ccccc1 +CCOC(=O)Nc1ccc(C(=O)Nc2ncccc2O)cc1 +Cc1ccncc1NC(=O)NCC(C)c1ccc(F)cc1F +Cc1noc(C(C)C)c1C(=O)NCC1Cc2ccccc2O1 +O=C(NCCNC(=O)C1CC1)c1cccc(Oc2ccccc2)c1 +CC(C)CN(CC(C)C)C(=O)C1CC(=O)Nc2ccccc21 +CCc1c(C(=O)N2CCC(O)CC2)cnn1-c1ccc(F)cc1 +CC1CN(C(=O)c2cc(Cl)ccn2)C(C)CO1 +O=C(Nc1cc(-c2ccsc2)no1)C1CCCC1 +COc1cc(NC(=O)c2ccno2)ccc1N1CCCC1=O +N#Cc1ccc(NC2C(=O)Nc3cccc(Br)c32)cc1 +Cc1cccnc1CC(C)NC(=O)c1ccc(Cn2cnnn2)cc1 +CN(C(=O)C1CCCN(S(C)(=O)=O)C1)C1(C#N)CCC1 +CC(OCCCNC(=O)c1ccco1)c1ccccc1 +CCc1c(C)sc(NC(=O)c2ccc(F)cc2)c1C(N)=O +CN(C)c1ccc(NC(=O)c2cccc3ncccc23)cn1 +O=C(Nc1ccon1)Nc1cc(C(F)(F)F)ccc1Cl +COC(=O)Nc1sc(C)c(C)c1C(=O)Nc1ccccc1OC +Cc1ccc(C(N)=O)cc1NC(=O)c1cccc(Nc2cnn(C)c2)c1 +Cc1ncc(CNC(=O)CSc2ccccc2F)s1 +Cc1nnc(CN(C)Cc2ccc(C(F)(F)F)cc2)o1 +Cc1cc(CNc2ccc3nnnn3n2)ccc1F +NC(=O)C1C(O)c2ccccc2C1c1ccccc1 +CCC(C)C(C)NC(=O)c1ccn(-c2ccc(F)cc2)n1 +O=C(COc1ccc2c(c1)CCC2)N1CCCC(N2CCNC2=O)C1 +Cc1cc(C)c(C#N)c(NCc2ccc3c(c2)OCO3)n1 +Cc1cc(=O)c(OCC(=O)Nc2ccc(Cn3cncn3)cc2)co1 +CCC(=O)N1CCc2cc(CNC(=O)c3ccccc3C)ccc21 +CC(C)CC(C(=O)NCc1ccc(=O)[nH]c1)N1CCCCC1=O +CC(=O)Nc1nc2cc(NC(=O)c3ccc(C)cc3)ccc2s1 +COc1ccc(OC(=O)Nc2ccccc2C)cc1 +CSc1ccc(NC(=O)NCC(F)(F)F)cc1 +Cc1cc(-c2nc(CCN3CCCC3=O)no2)cc(O)n1 +Cc1ccc(-c2nnc3sc(-c4cccc(O)c4)nn3c2=O)cc1 +CCCC(NC(=O)NCc1ncn(C)n1)c1ccc(F)cc1F +C=CCNC(=O)c1cc(-c2ccc(C)s2)nc2onc(C)c12 +Cc1ccc(NC(=O)c2ccc3c(c2)OCCO3)c(OC(F)F)c1 +CC(C)N(C)C(=O)c1cc(F)cc(Br)c1 +O=C(c1c[nH]c(=O)[nH]c1=O)N1CC2C3CCC(CC3)C2C1 +COc1ccc(C)cc1NC(=O)Nc1cnc(N2CCOCC2)nc1 +O=C(C1CCC1)N1CCN(c2cncc(Br)c2)CC1 +Cc1ccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)nc1 +OCC(O)C(O)c1nn(-c2ccccc2)c2nc3ccccc3nc12 +Cc1cc(S(N)(=O)=O)cc(NC(=O)C2CC2c2ccccc2)c1C +CC(C)c1ccc(NC(=O)Cn2ccccc2=O)cc1 +O=C(NCCOc1ccc2c(c1)OCO2)c1ccnc2ncccc12 +COc1ccnc(NC(=O)c2cc3ccccc3oc2=O)c1 +Cc1cc(C)c(C(=O)N2CCC(Nc3ccccc3F)CC2)c(=O)[nH]1 +Cc1ccc(CNC(=O)C2CN(C(=O)c3ccc(F)c(F)c3)C2)cc1 +Fc1cc(Cl)c2c(c1)C(c1ccncc1F)NCC2 +Cc1cc(C(=O)Nc2nnc(C3CCCCC3)o2)no1 +CCC(=O)NCCc1nc2ccccc2n1C(C)C(C)=O +CC(Oc1ccccc1N)C(=O)c1ccc2c(c1)OCCO2 +CCSc1ccc(Cl)cc1NC(=O)NCc1ncoc1C +Cc1nc(N(C)C)nc(C2=CC3=CC=NC3C=C2)c1C +COc1ccc(NC(=O)COc2nnc3ccccn23)cc1Cl +O=C(Cc1ccccc1)NCCNS(=O)(=O)c1ccc(F)cc1 +CCOc1ccc(S(=O)(=O)N(C)CCO)cc1C +Cc1cc(NC(=O)COC(=O)C(O)c2ccccc2)no1 +CC(C)Cc1ccc(C(O)CCC(=O)N2CCOCC2)cc1 +CS(=O)(=O)c1cccc(C(=O)NC2CC2c2ccccc2Cl)c1 +CCC(=O)N1CCCC(C(=O)NCc2sc(C)nc2CC)C1 +COc1ccc(CC2CCN(C(=O)COC(C)=O)CC2)cc1 +O=C(NC1CCSc2ccccc21)c1cc2ccccc2c(=O)[nH]1 +COc1ccc(Cl)cc1CC(=O)N1CCN(c2cnccn2)CC1 +Cc1c(CCO)nnn1-c1nc2c(s1)CCCC2 +CSc1ccccc1NC(=O)c1cn(C)c2ncccc12 +Fc1ccc(CNCCc2nc(-c3ccccn3)cs2)cc1 +O=C(CCc1cccs1)N1CCCC1c1ccsc1 +COc1cccc2c(C)c(C(=O)N(C)Cc3csc(C)n3)oc12 +C=C(C)COc1cccc(C(=O)N(C)C(C)C(O)c2ccccc2)c1 +CCn1cnnc1CNC(=O)c1cc2ccccc2oc1=O +Cc1ccccc1OC(=O)Cn1c(C)c(C)sc1=O +Nc1ccc(C(=O)NCCC2=CCCCC2)c(Cl)c1 +Cc1csc(CCCNC(=O)c2cnn(-c3ccc(F)cc3)n2)n1 +Cc1cc2ncn(CC(=O)NCc3cccc(Cl)c3)c2cc1C +O=C(NCCc1cnn(-c2ccccc2)c1)c1ccc2[nH]cnc2c1 +CN(C)C(=O)Cn1cnc(NC(=O)c2cn(C)nc2C(C)(C)C)n1 +CC(C)CCNc1ncnc(NC2CCCCC2)c1N +CCOc1ccc(OC)c(-c2cnn(CC)c(=O)c2C#N)c1 +O=C(Nc1cccc(C(F)(F)F)c1)c1occ2c1OCCO2 +CSc1ccc(NC(=O)C2CC(=O)N(C)C2c2cccnc2)cc1 +COc1ccc2[nH]cc(C3=CCN(CC(F)(F)F)CC3)c2c1 +C#Cc1cccc(NC(=O)Nc2cccc(OC)c2)c1 +CCCCCNC(=O)N1CCC(NC(N)=O)CC1 +CCCN(CC(F)F)C(=O)NC1CCN(c2ccccc2)C1=O +CC(C)(C)OC(=O)N1CCN(C(=O)C2COc3ccccc3O2)CC1 +O=C(c1cccc(OCC(F)F)n1)N1CCCCCC1 +Cc1n[nH]c(C)c1S(=O)(=O)N1CCCC(C#N)C1 +Oc1ccc(-c2csc(Cc3ccccc3)n2)c(O)c1 +Cc1cc2c(cc1C)N(Cc1ccccc1F)C(C1C=CC=NC1=O)N2 +O=C(C1Cc2cc(F)ccc2O1)N1CCc2cc(F)ccc2C1 +Cc1ncc(C(=O)NCCOc2cccc3c2OC(C)(C)C3)s1 +CC(=O)NCCNc1cc2c(cc1N)NC(=O)CC2 +CNC(=O)c1ccc(CN(C)C(=O)CCn2ccc3ccccc32)cc1 +CN(C(=O)CSc1nc(-c2ccccc2)c[nH]1)C1CC1 +O=C1CSc2ccc(C(=O)N3CCCC3C3CCCC3)cc2N1 +CC(C)Sc1nc2c(c(=O)[nH]c(=O)n2C)n1CCc1ccccc1 +CCn1cc(NC(=O)NC2CCc3ccccc32)cn1 +COC(=O)C1CN(CCn2cc(Br)cn2)CC(C)O1 +CCN(Cc1cccc(C(N)=O)c1)c1ccccc1 +Cn1c2c(ccc1=O)CCN(C(=O)NCc1cccnc1)CC2 +CCCc1cc2n[nH]c(=O)n2c(-c2cccc(F)c2)n1 +COc1c(CNCc2cccnc2-n2cccn2)c(C(C)C)nn1C +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)c1cccnc1 +Cc1noc(C)c1CC(=O)N1CCN(C(=O)C(C)C)CC1 +CCn1cnnc1CNC(=O)CN1C(=O)COc2ccc(Cl)cc21 +CC(C)Oc1ccc(Cl)cc1C(=O)N1CCC1 +C=CCSc1nnc(C(C)(C)n2cncn2)n1C +CCc1cnc(C(=O)NCc2nnc(C(C)C)n2C)s1 +O=C(c1ccon1)N(CCc1c[nH]c2ccccc12)Cc1cccnc1 +COc1cccc2c1OCC(C(=O)NCCCOC1CCCCC1)C2 +CCOC(=O)C(NC(C)=O)(Nc1cccc(C)c1)C(F)(F)F +Cc1nc(-c2ccncc2)sc1C(=O)Nc1cccc(Cl)c1 +Cc1nn(C)c(C)c1CC(=O)N1CCC(C(N)=O)c2ccccc21 +O=C(CC1CC2CCC1C2)N1CCC(O)(c2ccccn2)CC1 +O=C(CNC(=O)c1cc2ccccn2n1)NCc1ccc(F)cc1 +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)Nc1cccc(C#N)c1 +Cc1ccc(CNC(=O)c2ccccc2N2CCCC2=O)cc1 +O=C(C1CN(C(=O)C2CC2)c2ccccc2O1)N1CCOCC1 +Cc1ccc(NC(=O)C2COCC(=O)N2Cc2ccccc2)nc1 +Cc1cc2cc(NC(=O)c3n[nH]c4ccccc34)ccc2[nH]1 +CCCNC(=O)c1cccc(C(=O)Nc2ccc(C#N)cn2)c1 +COC1CCN(c2cc(-c3ccccc3)nc3ccnn23)C1 +O=C(Nc1ccccc1C(=O)N1CCCC1)c1cccc2ccccc12 +CCOc1ncccc1CNC(=O)N1CCOCC1 +CC(Sc1nc(N)cc(N)n1)C(=O)N(C(C)C)C(C)C +CCN(CC)C(=O)c1nc(CNC(=O)c2ccsc2)oc1C +COCC12CCCOC1CCN(C(=O)c1ccc(OC)c(F)c1)C2 +COc1ccc(-c2cc(-c3ccco3)nc(N)n2)c(OC)c1OC +Nc1nnc(CCc2ccccc2Br)o1 +CCN(CC)C(=O)c1ccccc1NC(=O)NCCc1cnn(C)c1 +C=CCN(C)S(=O)(=O)c1ccc(NC(=O)C2CCCC2)cc1 +Cc1cc(C)c(CNC(=O)c2ccc3c(c2)CCC3)c(=O)[nH]1 +CCCOc1ccc2cc(C(=O)Nc3ccccn3)c(=O)oc2c1 +Cc1sc(=O)n(CC(=O)N(Cc2cccs2)C2CC2)c1C +Cc1cccc(CN(C)Cc2nccn2C(F)F)c1 +CCOc1cccc(C(=O)Nc2cc(Cl)ccc2C(=O)NC)c1 +COc1ccc(CN2Cc3[nH]nc(C(=O)N(C)C)c3C2)cc1 +CN1CCc2nc(NC(=O)c3scnc3C3CC3)sc2C1 +CC1CCc2sc(C(=O)OCC3CC(=O)N(C4CC4)C3)cc2C1 +Cc1nn(C)c(C)c1NC(=O)c1ccc(OCc2nnnn2C)cc1 +CCCNC(=O)c1c2c(cn1-c1ccccc1)CCC2 +Cc1ccc(NC(=O)CCC2CCCOC2)cc1S(C)(=O)=O +NC(=O)Cn1c(=O)oc2ccc(Br)cc21 +Cc1nc2ccc(C(=O)NCCC(C)C)cc2nc1C +O=C(c1cc(F)ccc1F)C1CCN(C(=O)c2cnccn2)CC1 +CCn1nc(C2CCOCC2)nc1-c1cc(-c2ccccc2)on1 +Cc1cc(C)c(-c2c(NCC3CCCO3)c(=O)c2=O)cc1C +COCc1ccc(CNc2ccccc2-n2cccn2)o1 +COc1ncccc1CNC(=O)c1ccccc1C(F)(F)F +CCOC(=O)CC1CCCCN1C(=O)CNC(=O)c1ccccc1 +O=C(NCCn1cccc1)N1CCC(OCc2ccc(F)cc2)CC1 +CCOc1ccc(NC(=O)N(C)Cc2ccncc2)cc1C +CC(C)C(=O)Nc1ccc(Oc2ccc(S(N)(=O)=O)cc2)cc1 +CNC(=O)C1Cc2ccccc2CN1C(=O)C1CC=CCC1 +Cn1ccc(-c2nnc(NC(=O)CSc3ccccc3)o2)n1 +COCCCCNC(=O)NCc1sccc1C +COc1ccc(CNC(=O)C2CCN(C(=O)c3ccco3)CC2)cc1 +CN(C)C(C(=O)NC1CCOCC1)c1ccc(F)cc1 +COc1ccc(C2C(C(=O)OC(C)C)=C(C)Nc3ncnn32)cc1 +COCC(NC(=O)c1ccc(-c2cscn2)cc1)c1ccc(C)o1 +Cn1nccc1C(=O)N1CCCC(CCc2ccc(F)c(F)c2)C1 +CC(=O)NCc1ccc(-c2csc(NC(=O)c3cc(C)no3)n2)o1 +Cc1ccccc1C(=O)NCCC(=O)N1CCOC(C)C1 +CCS(=O)(=O)N1CCC(c2ccc(O)cc2)CC1 +CCOC(=O)CSc1nccn1-c1ccccc1C +Nc1c(C(=O)NCc2ccccc2)nnn1-c1ccc(Cl)cc1 +Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)NCc1ccco1 +O=c1[nH]c2cc3nc(-c4ccc5c(c4)OCCCO5)[nH]c3cc2[nH]1 +COc1ccc(OC)c(NCCN2CCOCC2)c1 +CCOc1ccc(C(=O)NC2CCCCNC2=O)o1 +CCCCC(=O)Nc1ccccc1N1CCN(S(C)(=O)=O)CC1 +CCOc1ccc2oc(C(=O)NC3CC3)c(C)c2c1 +CCC1COCCN1Cc1cc(OC)cc(OC)c1 +C#Cc1cccc(N(CC)C(=O)c2cccc(OC)c2F)c1 +Cc1ccc(CNC(=O)c2nn(C)c3ccc(F)cc3c2=O)cc1 +CCn1ncc(C(=O)Nc2ccc(C(C)=O)c(C)c2)c1C(F)(F)F +COc1ncnc(OC)c1CNc1ccc(Br)cc1 +CC(C)CNC(=O)Cn1cc(C(F)(F)F)ccc1=O +O=C(COC(=O)c1ccccc1Cl)NC1CCCCC1 +O=C(c1ccc(-c2ccccc2Cl)o1)N1CC(c2cccnc2)C1 +c1ccc(NCc2n[nH]nc2-c2ccccc2)cc1 +CN(C)C(=O)Sc1cccc(NC(=O)Cc2ccc[nH]2)c1 +Cc1cc(NC(=O)N(C)C(C)Cc2ccc(Cl)cc2)no1 +O=C(NCCCOCC1CC1)c1ccnc2ccccc12 +Cc1ccccc1C1CC(=O)Nc2c1cnn2C(C)(C)C +COc1cc(C)ccc1CNC(=O)c1cnn(-c2ccncc2)c1C +Cc1ccc2ncc(C(=O)Nc3ccnc(C)c3)c(=O)n2c1 +CC(=O)NCCNC(=O)N1CCCC1C1CCCC1 +CC(C)(C)c1ccccc1NC(=O)Cn1cnnn1 +COC(=O)c1cccc(NC(=O)C(C)Oc2ccccc2N)c1 +C#CCN(Cc1ccc(C)cc1)C(=O)C(C)Sc1nncn1C +C#Cc1cccc(NC(=O)c2cccc(OC)c2O)c1 +COc1ccc(OC)c(C(=O)Nc2ccccc2C(=O)NC2CC2)c1 +O=C(CN1c2cccc3cccc(c23)S1(=O)=O)NC1CCOCC1 +COCC(=O)N1CCC(NS(C)(=O)=O)C1Cc1ccccc1 +COCC(c1ccccn1)N(C)C(=O)c1c[nH]nc1-c1ccccc1 +Cc1cc(C(C)NC(=O)c2c[nH]c3cccc(F)c23)c(C)o1 +COc1ccc(C(=O)CNC(=O)C2CC2)c(OC)c1 +CC(C)(C)CCNC(=O)CSc1ccncc1 +COC(=O)c1cc(CNC(=O)N(C)C(C)c2ccccc2)oc1C +CC(NC(=O)N1CCOC(c2ccccc2Cl)C1)c1ccncc1 +CCNC(=O)CSc1ccc(-c2ccc(C)cc2)nn1 +O=C(NCCCNC(=O)c1nc2ccccc2s1)c1ccncc1 +O=C(Nc1ccccn1)c1cccnc1-c1nc2ccccc2s1 +COc1ccc(C2CC(=O)Nc3sc4c(c32)CCCC4)cc1OC +COc1cc(C(=O)N(C)Cc2ccc(O)cc2)cc(Cl)c1OC +CC1Sc2ccc(C(=O)NCc3cccnc3)cc2NC1=O +Cc1ccc2[nH]nc(C(=O)N(C)CCOCC3CC3)c2c1 +CCOc1ccccc1OCc1ccccc1C#N +Cn1cc(C(=O)NC2CCN(c3cccs3)CC2)c(C(C)(C)C)n1 +CC(C)CN(C(=O)COc1cccc(N)c1)C(C)C +Cc1cccc(C(=O)Nn2cnc3ccccc32)n1 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)N(CCCCO)C1CC1 +O=c1ccc(-c2ccco2)nn1Cc1ccc(F)cc1 +Cc1ccc(CC(=O)Nc2cccc(NC(N)=O)c2)cn1 +CN(C)c1ccccc1CNC(=O)Cn1ncc2ccccc21 +Cc1[nH]ncc1CCCNC(=O)c1sc2ncn(C)c(=O)c2c1C +CC(O)CNC(=O)C(N)c1cc(F)c(F)c(F)c1 +CC(=O)Nc1cc(NC(=O)Nc2cccc(Cl)c2F)ccc1C +C=CCSc1nnc2c(n1)[nH]c1c(C)cccc12 +CNC(=O)c1ccc(NC(=O)c2ccc(S(=O)C(C)C)cc2)cc1 +CCOc1cc(C2Nc3ccccc3C(=O)N2C)ccc1OC(F)F +Cc1nn2ccccc2c1C(=O)NCCNC(=O)NC1CCCCC1 +Cc1nc2scc(C)n2c1CNCCc1ccc(O)cc1 +COC(=O)c1cc(N)c(N2CCCC2)c(Cl)c1 +NC(=O)C1CCCCN1C(=O)c1nc(-c2ccccc2)oc1C1CC1 +CCc1cccc(C)c1NC(=O)CSc1nc(N)nc(N)n1 +Cc1ccccc1CC1(c2ccc(F)cc2)NC(N)=NC1=O +COc1ccc(F)cc1Cn1nnc(-c2ccc(F)cc2)n1 +OC1(C(F)(F)F)CCN(c2cc(NCC3CC3)ncn2)C1 +CCc1ccc(S(=O)(=O)NC(CO)Cc2ccccc2)s1 +CCN(Cc1ccc2c(c1)OCCO2)C(=O)Cc1c(C)nn(C)c1C +CCc1cccc(OC(=O)Cn2cnc3c(cnn3C)c2=O)c1 +COCCc1nc2c(C#N)ccc(-c3ccncc3)n2n1 +O=C(CC1CCCCC1)N1CCN(C(=O)Cn2cnnn2)CC1 +CCOC(=O)C(C)(O)CNc1nc(C)nc2sc3c(c12)CCC3 +CC(=O)NCCNC(=O)CCc1cccc(F)c1 +CCn1c(=O)c2c(nc3n2CCN3c2ccc(C)cc2C)n(C)c1=O +Cn1ccc(C(=O)N(CCO)C2CCCC2)cc1=O +Cc1ccc(F)cc1C(=O)NCc1cccc(C#N)c1 +COC(=O)NCC(=O)N1CCCC1c1ccccn1 +Cc1sc(NC(=O)CN2CCc3cc(F)ccc3C2)c(C#N)c1C +COC(C)(C)c1noc(-c2ccc(CNC(=O)OC(C)(C)C)o2)n1 +Cc1ccc(N(CCC#N)S(=O)(=O)c2cn(C(C)C)cn2)cc1 +CCC(C)CN(C)C(=O)c1ccc2c(c1)OCCO2 +CCN(Cc1cccc(F)c1)C(=O)CNC(=O)c1cccc(F)c1 +CCn1c(SCC(=O)NC(C)C)nnc1-c1cccc(C)c1 +CC(=O)c1cccc(NC(=O)c2cccc(C)n2)c1 +COC(=O)C1CCN(C(=O)CC2C=CCC2)c2ccccc21 +Cc1cc(NC(=O)CCSc2ccccc2C)no1 +CC(=O)NCC(=O)N(CCO)Cc1ccc(C)cc1 +COCC(NC(=O)c1ccc(-c2ccn[nH]2)cc1)c1ccnn1C +O=C(CNC(=O)c1cnn2c1SCC2)NCc1ccc(F)cc1 +O=C(Cc1noc2ccccc12)NCCCn1ccc2ccccc21 +CCOC(=O)C=C1CCN(C(=O)c2ccccc2)CC1 +COC(=O)CC1N=C(O)N(CCn2c(C)cc(C)c(C#N)c2=O)C1=O +COc1ccccc1CNc1nc(NCCO)nc2c1cnn2C +Cc1nc2c(C)cccn2c(=O)c1NC(=O)c1ccccc1Cl +CS(=O)(=O)c1ccc(Cl)c(C(=O)OC2CCOC2)c1 +COc1ccc(CCNC(=O)CSc2nc(C)cc(C)n2)cc1 +Cn1ccc(C(=O)NCC(=O)N2CCN(S(C)(=O)=O)CC2)n1 +O=c1c(=Cc2c[nH]c3ccccc23)sc2n1CCN=2 +CC(C)c1nc(NC(=O)CCc2nc(-c3ccncc3)no2)n[nH]1 +COc1cc(NCc2ccc(NC(C)=O)cc2)cc(OC)c1 +Cc1nc2c(Nc3cnc(-c4ccccc4)nc3)nc(N)nc2n1C +O=c1cc(CSc2nc(-c3cccs3)n[nH]2)occ1O +Cc1ccc(-c2ccc(=O)n(C(C)C(=O)Nc3cc(C)no3)n2)cc1 +Cc1sc2cc(C(=O)N(C)C)[nH]c2c1CN1CCOCC1 +CCNC(=O)CCc1nc(-c2ccccc2C)no1 +O=C(COc1ccccc1O)N1CCOC(CC2CCCCC2)C1 +Cc1cc(C)nc(NC(=O)CC2CC3CCC2C3)n1 +CC(C)n1cnnc1-c1ccccc1NC(=O)NCc1ncc[nH]1 +O=C(NCCCc1nc[nH]n1)C1(c2cccc(Br)c2)CC1 +Cc1cc(NC(=O)CCCNC(=O)c2ccc(F)cc2F)no1 +CCn1c(CNC(=O)c2cccnc2)cc2ccccc21 +CC(=O)c1ccc(NC(=O)C(C)Sc2nnnn2C(C)(C)C)cc1 +CCN(C(=O)Cn1ccnc1)c1nc2ccccc2s1 +CC(C)Oc1c(Cl)cccc1NCc1nsc(N(C)C)n1 +COc1ccc(-c2noc(-c3ccncc3)n2)cc1OC +O=C(CCc1nc(-c2ccco2)no1)NC1CCCC1 +CSc1nc(C)cc(C(=O)NC2CCCc3ccccc32)n1 +CC1CCN(C(=O)c2ccc(S(=O)(=O)C3CCCC3)cc2)CC1 +CC(C)CNc1nc(C(=O)Nc2nnc(C3CCC3)s2)cs1 +CCOC(=O)C1=C(C)N(c2cc(C)on2)C(=O)NC1c1ccccc1 +NC(=O)C1CCN(C(=O)CCc2ccccn2)CC1 +CSc1cccc(-c2nnc(NC(=O)c3ccc(F)cc3F)o2)c1 +COc1cccc(C(=O)N(C)Cc2cc3ccccc3o2)c1F +CC1CN(C(C)(C)CNC(=O)N(C)C(C)C2CC2)CC(C)O1 +O=C(c1ccc(OCC(F)F)nc1)N1CCCC1c1ccc[nH]1 +CCOCC(=O)Nc1cc(-c2cccc(C)c2C)n[nH]1 +CCCNC(=O)CN1CCN(C(=O)c2cccc(OC)c2)CC1 +COCC1(C(=O)NCCOc2cccc3ccc(C)nc23)CCC1 +CC(C)c1cc(C(=O)NCc2cccc(OCC(=O)N(C)C)c2)n[nH]1 +CCC(O)c1nc2ccccc2n1Cc1ccc(F)cc1 +CS(=O)(=O)NCCNC(=O)c1ccc(S(C)(=O)=O)cc1 +CC(C)c1csc(C(C#N)C(=O)CNC(=O)C(C)(C)C)n1 +CNC(=O)COC1COC2(CCCN(C(=O)c3ccccc3C)C2)C1 +CNC(=O)CN(C)S(=O)(=O)c1ccc(C)c(C)c1 +CNC(=O)c1ccc(NC(=O)c2nsc3ccccc23)cc1 +O=C(c1cnc(C2CCCO2)s1)N(CC1CC1)C1CCCCC1 +O=C(COC(=O)c1ccsc1)Nc1c(F)cccc1F +N#Cc1ccn2nc(-c3cc(F)cc(F)c3)nc2c1 +Cc1nnc(NCc2cccc(Cl)c2F)s1 +CC(Oc1cccc(C(C)(C)C)c1)C(=O)Nc1cnn(C)c1 +CCc1cc2cc(OC)c(OC)cc2c2c(=O)c(=O)c12 +O=C(CN1CCCCC1=O)Nc1nc(C2CC2)cs1 +Cc1ccc(C#N)cc1NC(=O)c1ccc(OCC(F)F)nc1 +O=C(c1cc(O)c2cc(Cl)ccc2c1)N1CCCC1 +CCC(=O)N1CCCC(C(=O)N2CCCC(c3ccccc3)CC2)C1 +COC(=O)C(NC(=O)c1cc2c(s1)CCCC2)c1cccc(O)c1 +COc1cc2c(cc1OC)CN(C(=O)CNC(C)=O)CC2 +Cc1csc(NC(=O)NCc2cccc(F)c2)n1 +COc1ncccc1C1NCCc2ccc(F)cc21 +Cc1nn(C)c2c1C(c1ccc(F)cc1Cl)CC(=O)N2 +COc1ccc(C(=O)N(C)C)cc1NCc1cc2cc(F)ccc2o1 +O=C(n1nnc2cc(Cl)c(Cl)cc21)C(F)(F)F +COc1ccc(C)cc1CC(C#N)c1c(C)noc1C +CC(C)CCNC(=O)c1ccc(N2CCCC2=O)cc1 +C#CCN1CCN(C(=O)CNC(=O)c2ccc3c(c2)CCC3)CC1 +CCOc1ccc(Cl)cc1S(=O)(=O)n1ccnc1 +CCC(NC(=O)N1CCC(NS(C)(=O)=O)CC1)C(C)C +CC(C)=CC(=O)OCCCn1nc2ccccn2c1=O +COC(=O)N(C)CC(=O)Nc1ccc(Cl)cc1Cl +Cc1ccc(C(=O)NCC(O)c2ccc(F)cc2)cc1C +COc1ccc2c(c1O)CCNC2C1CCC(=O)N1 +CCC(=O)N1CCc2cc(C(=O)NC(C)c3ccncc3)ccc21 +NC(=O)Cc1nc2ccccc2n1CC(O)c1cc(F)ccc1F +O=C(NCc1nnc2ccccn12)c1c[nH]c2cccc(F)c12 +CN1C(=O)C2CN(CCc3ccccc3)CCN2C(=O)C1CO +N#Cc1ccccc1C1NCCc2c(O)cccc21 +CCc1noc(CC)c1CNC(=O)C(CC)CC +COc1ccc(NC(=O)NCc2nnc3n2CCCCC3)cn1 +CCN(CC)C(=O)c1sc2nc(C)nc(N3CCCCC3)c2c1C +CC(=O)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1 +COc1cc2c(c(Cl)c1O)C(c1ccccc1)NCC2 +Cc1cc(C)cc(CCNC(=O)NC(C)CO)c1 +O=C(NCC(O)c1cccs1)Nc1ccccc1F +CC(C)c1ccc(C(=O)CC2(O)C(=O)N(C)c3ccccc32)cc1 +CCOC(=O)c1cc(-c2cc(CC)ccc2OC)nn1C +CC(NC(=O)Nc1ccc(C(=O)NC2CC2)cc1)C(=O)NC(C)(C)C +CC1CNC(=O)CCN1c1ccc(C(F)(F)F)cn1 +COC(=O)C1CCN(C(=O)CC2CCCC2)c2ccccc21 +CNc1nc(CNC(=O)Nc2cc(-n3cccc3)ccc2F)cs1 +Cc1noc2ncc(C(=O)NCCCN3CCCC3=O)cc12 +NC(=O)COC(=O)COc1ccc2cc(Br)ccc2c1 +Cc1ccc2c(c1)CCN2C(=O)CCS(=O)(=O)N(C)C +CCC(C)C(C)NC(=O)CN1C(=O)C(C)Oc2ccccc21 +CCc1ccc(NC(=O)Cn2nnc(-c3cccc(OC)c3)n2)cc1 +CC(Oc1ccc(C#N)cc1)C(=O)N(C)Cc1ccsc1 +O=S(=O)(Nc1ccccc1Cl)c1ccc2c(c1)OCCCO2 +CCS(=O)(=O)NCCNC(=O)c1cnn(-c2ccccn2)c1C +Nc1cc(C(=O)Nc2ccc(F)cc2F)ccc1F +CNC(=O)CN1CCN(C(=O)c2cccc(C)c2)CC1 +CCOCCCn1cc(O)c(=O)cc1CN1CCOCC1 +Cc1c(CC(=O)N2CCC(O)CC2)c(=O)oc2cc(O)cc(O)c12 +CC(C)C(=O)N1CCN(c2nnc(SCC(N)=O)s2)CC1 +Cc1nc(C)c(-c2csc(Nc3ccccn3)n2)s1 +Cc1cc(C(O)C(=O)N2CCNCC2)ccc1F +CC(C)Cn1c(CO)cnc1SCc1c(F)cccc1F +CCCNC1=NS(=O)(=O)c2cc(N3CCCC3)ccc2N1 +Cc1cccc(C)c1Oc1ncccc1CNC(=O)CNC(N)=O +CC(C)(C)NC(=O)CN1CCN(CC(=O)N2CCCCCC2)CC1 +Cc1cnc(C(=O)N2CCOC3C(OCC(C)C)CCC32)cn1 +N#CCCN(C(=O)Cc1cccs1)c1ccccc1 +Cc1ccccc1C1CCN(C(=O)OC(C)(C)C)CC1O +Cc1c(C(=O)NC(C)c2ccc(F)cc2F)cnn1-c1ccncc1 +COCC(=O)Nc1cc(C(=O)N(C(C)C)C(C)C)cn(C)c1=O +CC(C)C(NC(=O)Cc1ccccc1O)c1ccc2c(c1)OCCO2 +CCSc1nc(CC(=O)NCc2ccc(CC)cn2)cs1 +CCC(C)Oc1cccc(-c2cnn(C)c(=O)c2C#N)c1 +O=C(CCCn1cnnn1)N1CCOC(c2ccc(F)cc2)C1 +CCc1ccc(C(=O)N2CCOc3cc(F)ccc32)o1 +CC(C)(C)n1ncc2c(=O)[nH]c(NCC3CCCC3)nc21 +Cc1cnc2c(c1)N(C(=O)c1cc(C)on1)CCO2 +CC(=O)Oc1ccc(C(=O)NCCN2CCOCC2)cc1 +CC(=O)NCc1ccc(-c2nc(Cc3ccccc3)sc2C)s1 +CC(C)c1ccc(-c2ccnc3nc(N)nn23)cc1 +COC(=O)C(NS(=O)(=O)c1ccc(F)cc1)C(C)C +OC1(c2cn(Cc3ccccc3)nn2)CCCCC1 +CCOc1ccc(F)c(C(=O)N(C)CCN2CCOCC2)c1F +COc1ccc(OC(C)C)c(NC(=O)NCc2nc(C)sc2C)c1 +CNC(=O)c1cccc(NCC(=O)Nc2cccc(F)c2)c1C +CCCCN(C)C(=O)c1ccccc1N(C)C(=O)C1CC1 +CCCCC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCOCC2)c1 +CC(=O)N1CCN(S(=O)(=O)CC(C)CO)CC1 +Cc1[nH]ncc1CCCNC(=O)Cn1c(=O)cnc2ccccc21 +Cn1nnnc1SCCNC(=O)Nc1ccc(Cl)cc1 +Cc1sc(=O)n(CC(=O)N2CCN(c3ccccc3O)CC2)c1C +COC(=O)c1ccoc1COc1cc(C)ccc1NC(C)=O +CC(C)c1nnsc1CN1CCCC2(CC1)CN(C)C(=O)O2 +CN(CC(N)=O)C(=O)c1cc2sc(N(C)C)nc2s1 +CC(C)C(C)NC(=O)NCCCNC(=O)c1ccc(F)cc1 +CC1CCN(C(=O)C2CC(=O)N(C(C)C)C2)C(C)C1 +CCCc1nc(N2Cc3cnn(CCO)c3C2)no1 +O=C(Cc1c[nH]c2ccccc12)N1CC(O)C(N2CCOCC2)C1 +O=C(CSc1c[nH]c2ccccc12)NCCc1ccccc1 +COc1ccc(NC(C)=O)cc1NC(=O)COc1ccc(C)cc1C +Cc1cccc(C(=O)NCC(=O)Nc2cccc(O)c2F)c1 +COCCOc1ccccc1CN1CCOC(c2ccccc2F)C1 +O=C(Cn1nc(-c2ccc(Cl)cc2)ccc1=O)NCC1CCCO1 +CN(C)C(=O)CN(CC(F)(F)F)C(=O)c1cccc(C#N)c1 +Cn1c(C(F)(F)F)nn(CC(=O)OC(C)(C)C)c1=O +CCCC(=O)NCCCc1nc2ccccc2n1C +Cc1cn(-c2ccccc2)nc1NC(=O)N1CCCC(O)C1 +CC1CCCC(C#N)(NS(=O)(=O)c2cccc3ncccc23)C1 +CN(C)C(=O)CN(C)C(=O)Cn1cccc(C(F)(F)F)c1=O +Cn1c(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)cc2ccccc21 +CCCNC(=O)c1cccc(S(=O)(=O)N(CC)c2ccccc2)c1 +CCN(CCO)C(=O)c1ccc(Oc2ccccc2)nc1 +COc1ncc(C)cc1NC(=O)c1cnc(C2CCCO2)s1 +Cc1cc(C(=O)CCC(=O)NC(C)Cn2cccn2)c(C)s1 +N#Cc1ccccc1C(N)c1nnc(-c2ccnnc2)o1 +Cc1ccc(-c2cc(CNC(=O)NC3CCCCNC3=O)on2)cc1 +c1cnn(CCN2CCOC(Cn3cccn3)C2)c1 +Cc1nc(C)n(Cc2coc(-c3ccc(S(C)(=O)=O)cc3)n2)n1 +Cc1cccc(OC(C)C(=O)N(C(C)C)C(C)C)c1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)Nc1ccnn1CC(C)C +COc1cccc(C(C)Nc2ccc(OC)nc2)c1 +CN(C)C(=O)COc1cccc(CNC(=O)Nc2ccn(C)n2)c1 +COc1ccc(C)cc1NCC(=O)N(C)Cc1ccccc1F +COc1ccc(C(C)C)cc1S(=O)(=O)Nc1ccncc1 +COCC(O)CN(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +CC(C)(C)c1noc(CSc2nnc(C(C)(C)C)o2)n1 +Nc1cc(C(=O)CN2CCc3ccccc32)ccc1F +O=C1CCc2cc(C(=O)c3ccc(O)cc3)ccc2O1 +Cc1csc(-c2ccc(NC(=O)NCc3csc(C)n3)cc2)n1 +CNS(=O)(=O)c1ccc(C(=O)NCC(C)(C)c2ccncc2)cc1 +CNC(=O)c1cccc(NC(=O)N2CCC3(CCCCC3)CC2)c1 +Cn1ncc2c1N=C(O)CC2c1ccccc1OCc1ccccn1 +CC(C)CNS(=O)(=O)c1ccc(C(=O)Nc2nccs2)cc1 +COC(=O)C1=C(c2ccccc2)NC(=O)NC1c1cccnc1 +CCn1c(C)cc(C(=O)NCc2ccc(OC)c(OC)c2)c1C +CCC(O)c1ccc2c(c1)CN(C(=O)c1cccs1)CC2 +COc1ccc(COc2c(C)cccc2C(C)O)cc1OC +CC(NC(=O)c1cn(C2CCCCC2)nn1)c1ccc(F)cc1 +O=C1CCCCN1CCCc1nc(C2CCOC2)no1 +CCN(c1ccc(Cl)c(N)c1)S(=O)(=O)c1ccccc1 +COc1ccc(OC)c(C(CCO)CC(C)C)c1 +CCc1nn2c(=O)cc(CNc3cccc(Cl)c3)nc2s1 +CCC1CCC(CNC(=O)CNC(=O)OC)CC1 +O=C(CCc1ccc2c(c1)OCO2)NCC(O)c1ccc(F)c(F)c1 +CN(C)S(=O)(=O)CCNC(=O)Nc1cccc(C#N)c1 +Cc1cc2nc(C(C)C)cc(N(C)Cc3noc(C)n3)n2n1 +CC(C)C(NC(=O)c1ccccc1F)C(=O)NCCO +CCOc1ccccc1C(=O)Nc1ccc(N2CCNC2=O)cc1 +Cc1sc(-n2cnnn2)c(C(=O)NC2CCCCC2)c1C +Cc1ccc(=O)n(CC(=O)N2CCC3(CCCN(CCO)C3=O)C2)n1 +CC(C)Oc1c(Br)cncc1Br +Cc1ccc(N)c(S(=O)(=O)NCc2ccco2)c1C +COc1ccccc1NC(=O)C(C)OC(=O)c1ccoc1 +CC(=O)N1CCC(NC(=O)NCCCOC(C)C)CC1 +O=C(Cc1ccc(F)cc1)N1CCN(CCCO)CC1 +Cc1nc2nc(N)nc(SCc3ccccc3)c2[nH]1 +COc1ccc(-c2nnnn2-c2ccc(F)c(F)c2)cc1 +CCC(C)C(NC(=O)CN1CCOCC1)c1nc2ccccc2[nH]1 +O=C1CCCCN1CC(=O)N1CCCC(Nc2ccc(F)cc2)C1 +COc1cc(C(C)Nc2ccccc2F)ccc1O +N#Cc1ccc(N2CCC3C(CCC(=O)N3C3CC3)C2)cn1 +N#CC(NC(=O)c1ncn(-c2ccccc2)n1)c1ccc(F)cc1F +CC(C)c1ccc(C2(C(=O)NCCS(N)(=O)=O)CCC2)cc1 +C#CCOc1ccccc1CNCC(O)c1ccc(Cl)cc1 +Cc1nc(C(=O)NCC2Cc3ccccc3O2)cs1 +CCCc1noc(Cn2ccc(-c3ccccc3)n2)n1 +CC1CCC2C(C1)c1c([nH]c(=O)[nH]c1=O)OC2(C)C +Cc1csc(CNc2ccc3c(c2)C(=O)CCC3)n1 +CCN(CCC#N)C(=O)CN(C)c1ccc2ccccc2c1 +CN(CC(=O)Nc1ccc(F)cc1N)c1ccccc1 +CC(C)n1ccc(CC(=O)Nc2ccccc2N2CCCCC2)n1 +Cc1noc(COC2CCCN(C(=O)c3ccsc3)C2)n1 +Cc1cccc(CN(Cc2ccccn2)C(=O)c2ccc(C)[nH]c2=O)c1 +COc1ccc(F)c(C(=O)N2CCC(C(O)CC(C)C)CC2)c1F +Cc1ccc(N2CCC(NC(=O)c3cscn3)C2=O)cc1 +CN(C)c1cccc(N2Cc3cccc(N)c3C2)c1 +CC(C)CCNC(=O)CCSc1ccc2c(c1)OCCO2 +CN(Cc1nnc2n1CCC2)C(=O)c1ccc(C(F)(F)F)nc1 +Cc1nc(C2CCCN2C(=O)C2Cc3ccccc3C(=O)O2)no1 +CC(C)(C)n1ncc2c1N=C(O)CC21C(=O)Nc2ccc(Cl)cc21 +Nc1cc(F)c(NCCc2ccc(F)cc2)c(F)c1 +CC(=O)Nc1cc(NC(=O)N(C)Cc2ccccc2Cl)ccc1C +O=C(Cc1ccccc1)NCCC(=O)N1CCCc2ccccc21 +Nc1cccc2cc(S(=O)(=O)c3ccccc3)cnc12 +CN=c1scc(-c2ccc(NS(C)(=O)=O)cc2)n1C +COCCOC(=O)c1nc(-c2ccccc2)n(-c2ccccc2)n1 +COC(=O)c1ccc2c(c1)CN(CC(O)CO)CC2 +Cc1nc(NC(=O)Cn2nnc3ccccc3c2=O)sc1C +CSc1nc(C)cc(NCCNc2cc(C)nc(SC)n2)n1 +Cc1nc(C)c(CC(=O)N2CCCCC2c2cc[nH]n2)s1 +COC(=O)C1CCN(C(=O)c2ccnn2C)c2ccccc21 +Cc1ccc(SCCS(=O)(=O)c2ccccc2)cc1 +CCOCC(=O)N1CCC(Nc2cccn3ncnc23)CC1 +CC1Oc2ccc(NC(=O)NCCc3ccccc3F)cc2NC1=O +Cc1nc(-c2nccn2CC(c2cccnc2)N2CCOCC2)co1 +CCOC(=O)c1csc(NC(=O)c2ccc(F)cc2Cl)n1 +Cc1cc(-c2nn3c(-c4ccc(Cl)cc4F)nnc3s2)n[nH]1 +Cc1cc(=O)oc2cc(NC(=O)c3ccccn3)ccc12 +CC(NC(=O)NCc1ncn(C)n1)c1ccc(OC(F)F)cc1 +O=C(NCc1ccccc1Cl)c1ccc2c(c1)OCCCO2 +CN(CCCc1nc2ccccc2[nH]1)C(=O)c1ccc(O)cc1F +CC(CN1CCOCC1)NC(=O)Cn1nc2ccccn2c1=O +COC(=O)c1nn(C)c(N)c1-c1ccc(Cl)cc1Cl +Cc1ncsc1C(=O)N1CCCSc2ccccc21 +Cc1ccc(CNC(=O)NCc2csc(C)n2)cn1 +CCn1c(=O)c2c3c(sc2n2c(C)nnc12)CCCC3 +CC(=O)Nc1cccc(-c2nc3ncccc3o2)c1C +O=C(N=c1[nH]c2ccccc2s1)c1ccc(F)cc1-n1cnnn1 +Cc1cc(C(=O)N2CCC(C)CC2)ccc1NC(=O)Cn1cccn1 +Cc1ncc(CNc2nc3cc(Cl)ccc3s2)s1 +Cc1ccc2nc(-c3ccco3)nc(NCCNC(=O)C3CC3)c2c1 +CCCCCOC(C)C(=O)Nc1ccc(Cl)c(N)c1 +CCOC(C)C(=O)N1CC(C)(C)Sc2ccccc21 +Cc1ccc(C(C)NC(=O)Cn2ccc(=O)c3ccccc32)cc1F +Cc1cccc(C)c1NC(=O)CNC(=O)c1ccc(F)cc1Cl +Cc1ccc(NC(=O)C(C)C)cc1NC(=O)c1ccc[nH]1 +CCc1cccc(CC)c1NCc1nc(C)c(C(C)=O)s1 +COCCSc1nnc(-c2ccncc2)n1-c1ccccc1 +CCOCc1ccc(CNC(=O)N(C)Cc2cc(C)on2)cc1 +CC1CCCN(C(=O)c2ccc(C(F)(F)F)cc2)C1 +O=C(NCCc1ccncc1)c1ccn(-c2ccc3ccccn23)n1 +CC(C(=O)Nc1ccc(F)cc1N)n1cc(Cl)cn1 +COc1cc(CO)c(OCc2ccc(F)c(F)c2)c(CO)c1 +COc1ccc(-n2ccnc2SCC(=O)N2CCCCCC2)cc1 +CNc1oc(-c2cccs2)nc1S(=O)(=O)c1ccccc1 +COC(=O)CC(NC(=O)c1cc(C(C)=O)c[nH]1)c1cccs1 +O=C(Nc1ccc(Cl)cc1Cl)N1CCC2(CC1)OCCO2 +CC(=O)N(C)CCc1noc(COc2cccc(Cl)c2)n1 +CCN(C)C(=O)c1cccc(OC(=O)COc2ccccc2C)c1 +COc1ccc(Nc2ncnc(N3CCOCC3)c2N)c(OC)c1 +CS(=O)(=O)N1CCN(C(=O)c2cnn3ccccc23)CC1 +Cc1c(NCc2ncc(-c3ccc(Cl)cc3)o2)cccc1C(N)=O +COC(=O)CNC(=O)CCOc1cccc(F)c1 +Cc1nc2cc(NC(=O)c3csc(S(N)(=O)=O)c3)ccc2o1 +CN(CC(=O)NCC1COCCO1)c1ccc(Cl)cn1 +CC(C)S(=O)(=O)c1ccccc1C(=O)Nc1ccc[nH]c1=O +Cc1ccccc1Cn1nnc(C(=O)OC2CCCCC2)c1N +CN(C)S(=O)(=O)c1ccccc1-c1cc(O)cc(C#N)c1 +COc1cc(Br)cc(NC(=O)N(CCO)C(C)C)c1 +CCN1CC(C(=O)NCc2cnc(SC)n2C)CC1=O +Cc1oc2nc[nH]c(=O)c2c1C(=O)NC(C)c1ccco1 +CC(C)NC(=O)c1nn(-c2ccc(F)cc2)c2ccccc2c1=O +Cn1nnnc1SCCOc1cccc(Cl)c1 +CCCc1noc(C2CCCN(C(=O)c3cccs3)C2)n1 +O=C(c1cc2c(s1)-c1ccccc1OC2)N1CCOCC1 +CNC(=O)Cc1ccc(NC(=O)c2c(F)cccc2Cl)cc1 +O=C(Cc1ccccc1Cl)N1CC(c2ccncc2)C1 +Cc1cc(NC(=O)COc2cccc(F)c2)no1 +CC(C)Oc1ccccc1CNC(=O)c1ccn2cncc2c1 +CN(C(=O)c1cnc(C2CCCO2)s1)c1ncccc1F +Brc1cncnc1-c1ccc2c(c1)CCC2 +O=C1CC(c2ccc(F)cc2Cl)c2ncn(-c3cccnc3)c2N1 +O=C(Nc1ccc(OCc2ccccc2)cc1)c1cnccn1 +Cc1ccc(C(=O)NCc2ccc(N3CCCCC3=O)cc2)c(=O)[nH]1 +COC(=O)C1CCCN1C(=O)CNC(=O)c1cccs1 +CC(C)Cn1ncnc1CS(=O)(=O)c1ccc(F)c(Cl)c1 +COc1ccc(OC)c(NC(=O)CSc2ccc(F)c(F)c2)c1 +Cn1ccc2c(C(=O)Nc3ccc4[nH]nc(C(N)=O)c4c3)cccc21 +Cc1cc(N)ccc1N1CCCC1c1ccccc1 +Cc1ccn2c(=NC(=O)CCc3ncc(-c4ccccc4)o3)[nH]nc2c1 +CC(C(=O)N1CCN(C(=O)CO)CC1)c1cccs1 +COc1ccccc1CN1CCN(C(=O)Cc2ccccc2O)CC1 +Cn1cc(C(N)=O)cc1C(=O)OCCc1ccc(F)cc1 +NC(=O)C1(CNC(=O)c2cc(F)cc(F)c2)CCOCC1 +CC(C)(C)OC(=O)N1CCC(n2c(=O)oc3ccccc32)C1 +Cn1nncc1CN1CCOC(c2cccc(Br)c2)C1 +Cc1ccc(C(=O)NCc2cccc(CN3CCCC3=O)c2)c(O)c1 +O=C(Cn1c(SC(F)F)nc2ccccc21)NC1CCCC1 +O=C(Cn1ccnc1)NCC(O)c1c(Cl)cccc1Cl +CCN(Cc1cnn(C)c1)C(=O)CNC(=O)OC +CC(C)(C)NC(=O)CNc1cccc(C(=O)NC(C)(C)C)c1 +COc1cc(C(C)=O)ccc1OCc1nc(-c2ccccc2)no1 +O=C(CCN1C(=O)COc2ccccc21)Nc1ccc(F)cc1F +O=C(Cc1csc(-c2ncccn2)n1)Nc1nncs1 +CCn1nc(C)c(Cl)c1C(=O)NCCc1ccccc1 +Cn1c(-n2ncc(Cl)c(Cl)c2=O)nc2ccccc21 +COC(=O)Cn1c(=O)oc2cc(S(=O)(=O)N(C)C)ccc21 +NC(=O)c1ccc(CSc2ncc(Cl)cc2Cl)cc1 +NC(=O)N1CCCC(C(=O)NCCCOc2ccccc2)C1 +C=CCn1c(C)cc(C(=O)COC(=O)c2ccccc2O)c1C +O=C(c1c(F)cccc1F)N1CCN(Cc2cncs2)CC1 +CC(NCc1ccc(-n2cncn2)c(F)c1)C(=O)N1CCCCC1 +Cn1nnc2c(N3CC(C(=O)NCCC4=CCCCC4)C3)ncnc21 +CC(C)Oc1ccc(-c2cc(C(=O)NCc3ccco3)no2)cc1 +Cc1nc(C(C)NC(=O)NCc2cccc(C(F)(F)F)c2)cs1 +COc1ccc(C(=O)NC2CCCCNC2=O)cc1F +O=C(Nc1ccc2c(c1)OCCO2)c1ccccc1Cl +CCOC(=O)C(C)(NC1CCCCC1)c1ccccn1 +COc1ccccc1OCc1nnc(-c2cnc3onc(C)c3c2)o1 +CCOc1ccc(N)cc1S(=O)(=O)Nc1cn[nH]c1 +Cc1nccc(N2CCN(C(=O)NCc3ccccc3Cl)CC2)n1 +Nc1ccc(S(=O)(=O)CCCOc2ccccc2)cc1 +Cc1nc2c(nc3c(Cl)cc(F)cn32)c(=O)[nH]1 +COC(=O)c1ccc(CSc2nnc3ccccn23)o1 +O=C(NCCO)c1ccc(-c2ccc(F)c(F)c2)o1 +CCOC(=O)CCCNC(=O)c1cccc(Br)c1 +C#CCOC(=O)c1ccc(S(=O)(=O)N2CC(C)CC(C)C2)cc1 +CCN(C(=O)c1cc2c([nH]c1=O)CCCC2)c1ccc(F)c(F)c1 +COc1ccccc1-c1csc(NC(=O)c2ccco2)n1 +NC(=O)N1CCCN(C(=O)c2cccnc2OCC(F)F)CC1 +N#Cc1ccc(OCCOc2cccc(Oc3ncccn3)c2)cc1 +Cc1cc(F)cc2c1CCNC2C(=O)Cc1ccc(O)cc1 +CC(NC(=O)c1ccc(C#N)cc1)c1ccc(F)cc1 +O=C(CC1C=CCC1)NCC1CCN(c2ccccc2)C1 +Cn1c(CNC(=O)CCc2nc3ccccc3[nH]2)cc(=O)n(C)c1=O +Cc1ocnc1C(=O)NCC1(c2ccc(F)cc2F)CC1 +CCCc1ccc(C(=O)Nc2nnc(C3CC3)s2)cc1 +COC(=O)CN(c1ccc(Oc2ccccc2)cc1)S(C)(=O)=O +CN(Cc1ccccc1N1CCCC1)C(=O)c1ccc(O)c(Cl)c1 +Cc1ccsc1C(=O)NCCc1nc2ccccc2s1 +Cc1cc(C(=O)Nc2nc3c(F)cccc3s2)on1 +O=C(Cc1cc(-c2ccc3c(c2)OCCO3)on1)Nc1ccccn1 +O=C(COc1ccc(Cl)cc1)N1CC(n2ccnn2)C1 +CNS(=O)(=O)c1ccc(CNC(=O)CCc2ccco2)cc1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)CSc1nncs1 +CC(C)N(Cc1cccnc1)C(=O)Cc1ccc[nH]1 +COC(=O)c1ccc(-n2ncc(-c3ccccc3OC)c2N)cc1 +CNC(=O)c1ccc(NC(=O)c2nc3nc(C)cc(C)n3n2)cc1 +CC1CCC(C)N1C(=O)NCC(C)(C)c1ccncc1 +Cc1nc2c(=O)n(Cc3ccccc3)nc(-c3cccs3)c2s1 +Nn1c(SCc2ccc(Cc3ccccc3)cc2)nncc1=O +C#CCOC(=O)c1ccccc1Oc1nc(OC)cc(OC)n1 +CC(C)c1nc2ccc(F)c(F)c2n1-c1ccc(C#N)cn1 +Cc1ccc(NC(=O)CCNC(=O)N(C)CC2CCCO2)nc1 +O=C(Nc1ccc(F)cc1Br)N1CCOCC1 +Cc1cnccc1C1NCCc2c(F)ccc(Cl)c21 +O=S(=O)(c1ccccc1)c1ccc(-n2ccnc2)cc1 +CCNS(=O)(=O)c1cccc(C(=O)NCc2ccco2)c1 +CCCN1CCN(C(=O)c2cnc3cc(C)ccn3c2=O)CC1 +c1ccc(-c2cc3ncccc3c(N3CCOCC3)n2)nc1 +COCC(NC(=O)c1ccc(-c2nc(C)no2)cc1)C(N)=O +O=C(COc1ccccc1F)NCCc1cccs1 +Cc1cc(C)c(C(=O)N2Cc3cnc(-c4ccccc4)nc3C2)cn1 +CC(NC(=O)c1ccncc1)C1=CCCN(CCn2cccc2)C1 +Cc1ccc2c(c1)CCC21CCN(C(=O)N(C)C)CC1 +CN(Cc1cccnc1)C(=O)NCCCN1CCCC1=O +Cc1ccc(C(=O)CNC(=O)c2ccccc2)c(C)c1 +CCCOC(=O)C(C)n1nc(C#N)cc1-c1ccco1 +COCCn1cc(CCNC(=O)NC2CCCCC2)c2cccnc21 +CC(C)C(=O)c1ccccc1NC(=O)C1CC=CC1 +CC(NC(=O)CC1CCCC1)c1ccc(NC(N)=O)cc1 +COc1cccc(C(=O)N2CCc3ccc(N)cc32)c1O +C#CCNC(=O)CSc1nnc(C2CC2)n1CC=C +CN(CCO)C(=O)Nc1ccc(C(C#N)c2ccccc2)c(Cl)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)C1CC(=O)N(C)C1 +Brc1cccc(Cn2ccnc2Cc2ccccn2)c1 +Cc1occc1-c1nnc(SCCOc2ccc(C#N)cc2)o1 +NC(=O)NCCCCC(=O)OC1c2ccccc2-c2ccccc21 +Cc1cc(N2CCC(=O)CC2)nc(-n2nc(C)cc2C)n1 +CC(CC1CCCCC1)C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +O=C(Nc1ccccc1OCc1cscn1)c1ccnnc1 +O=S(=O)(NCC(O)(c1ccccc1)C1CC1)c1cccs1 +CC(C)(C)OC(=O)N1CCCCC1c1cccnc1 +Cc1cc(C)n(C2CCN(Cc3nc4ccccc4[nH]3)CC2)n1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCCCO)O2 +O=C(NCc1nc(CCc2ccccc2)no1)C1CCCC1 +O=c1ccc(-c2ccc(S(=O)(=O)N3CCCCC3)o2)n[nH]1 +CCNc1nc(CC(=O)Nc2ccc(C)cc2C)cs1 +CC(=O)N1c2ncnn2C(c2ccc(C)cc2)CC1c1ccccc1 +CC1CCC(NC(=O)C2CCN(C(=O)OC(C)(C)C)C2)CC1 +CC(C)NC(=O)CNC(=O)CC1Oc2ccccc2NC1=O +CC(C)(C)CC(=O)Nc1ccc(S(C)(=O)=O)nc1 +NS(=O)(=O)N1CCN(C(=O)c2cccc(F)c2F)CC1 +Nc1ncnc2c1cnn2-c1ccc(Cl)cc1F +COc1ccccc1N1CCN(C(=O)c2cc(C)on2)CC1 +COc1cc(C(=O)Nc2cccc3nc(C)ccc23)on1 +CCn1nc(C(=O)N2CCCC(c3nc4ccccc4[nH]3)C2)cc1C +Cc1cc2nc(C(C)C)cc(NC3COCC3N3CCOCC3)n2n1 +O=S(=O)(NCCc1nc2ccccc2s1)N1CCCCCC1 +CCOC(=O)c1sc(NC(=O)C2CCCO2)nc1-c1ccccc1 +COc1ccc(C2=CCN(C(=O)Cc3c(C)noc3C)CC2)cc1 +O=C(Cn1nc2ccccn2c1=O)Nc1ccccc1 +Cc1nc(C)c(C(=O)N2CCn3c(nnc3C(F)(F)F)C2)s1 +c1ccc(-c2nnc3ccc(N4CCC5(CCOC5)C4)nn23)cc1 +C=CC(C(O)c1ccccc1)n1nnc2ccccc21 +CC(NC(=O)c1ccoc1)C(=O)N(C)C(C)c1cc(F)ccc1F +COCCn1cc2c3c(cccc31)CN(C(=O)c1ccccn1)CC2 +COc1ccc(-c2nc(C)nc(C)c2N)c(OC)c1C +CS(=O)(=O)c1cccc(C(=O)Nc2ccnc3ccnn23)c1 +c1cc2[nH]ncc2cc1NCc1cnc(C2CC2)s1 +CSc1ccc(OC(C)C(=O)Nc2ccccn2)cc1 +CNC(=O)CN(C)S(=O)(=O)c1ccc(C)c(Cl)c1 +CCCc1nn(CC(N)=O)c(=O)c2cc3ccsc3n12 +O=C(NC1CC1)c1cccc(OC(=O)c2cc(-c3ccccc3)no2)c1 +CC(CO)NC(=O)CNC(=O)c1ccc(N)cc1 +COc1ccccc1S(=O)(=O)Nc1ccc2c(c1)CN(C)C(=O)N2 +CCOC(=O)C(Sc1nc(C)cc(=O)[nH]1)c1ccccc1 +Cc1ncc(CN(CC(=O)N(C)C)CC(F)(F)F)s1 +CC(=O)N1CCN(C(=O)c2ccc(Cl)c(Cl)c2)CC1 +Cc1ccc(-c2nc(NC(=O)c3c[nH]c(=O)cc3C)n[nH]2)o1 +Cc1cc(C(=O)N2CCc3ncnc(-c4ccncc4)c3CC2)no1 +CN(C)c1ncc2c(n1)CN(C(=O)c1ccccc1F)CC2 +COc1cccc(C(N)c2nc(-c3ccccc3Cl)n[nH]2)c1 +Cc1cc(COc2cc(F)ccc2C(C)O)no1 +CC(NC(=O)COc1ccc(-n2cnnn2)cc1)c1ccco1 +CC(C)c1nnc(CCc2nc(-c3ccc(C#N)cn3)no2)o1 +Cc1ccc2c(c1)C(=O)CC2CC(=O)N1CCCCC1 +O=C(NC1CC1)c1cccc(NC(=O)c2cc3ccccc3o2)c1 +O=C(c1ccsc1)N1CCOC2C(OCc3ccccn3)CCC21 +CC(OC(=O)c1cc(Cl)c2c(c1)OCCO2)c1ccccn1 +Cc1cc(C)c(CNC(=O)Cc2cnn(-c3ccccc3)c2)c(=O)[nH]1 +CCOC(=O)c1nnsc1NC(=O)c1cccc(-n2cccc2)c1 +CC(C)(C)c1csc(NC(=O)c2ccc3c(c2)OCCO3)n1 +COC(=O)C1=C(C)NC(=O)NC1C(Cl)(Cl)Cl +CC(=O)N1CCc2ccc(NC(=O)CCc3ccccc3)cc2C1 +O=C(NCC1(O)CCOC1)c1cccc2[nH]ccc12 +O=C(NCCNC(=O)c1ccnc2c1OCO2)Nc1ccccc1 +Cc1nc2c(c(NCC(=O)NC(C)C)n1)Cc1ccccc1OC2 +CC(C)NC(=O)CN(C)C(=O)c1ccc(-n2ccnc2)nc1 +CCOc1ccc(F)c(C(=O)Nc2cnc(C(C)(C)C)nc2)c1F +Cc1nn2c(C#N)c(-c3ccc(Cl)c(Cl)c3)nc2s1 +N#CCc1ccc(NC(=O)N2CCc3cc(F)ccc3C2)cc1 +Cc1ncsc1C(=O)N1CCCCCC1c1ccncc1 +Cc1ccn2c(=NC(=O)c3cc(F)c(F)cc3Cl)[nH]nc2c1 +CSc1ccc(C(C)Nc2ccc(=O)n(C)c2)cc1 +O=C(C1COc2ccccc2C1)N1CCc2[nH]ncc2C1 +Cc1nn(C)c2nc(NCC3CCOC3)sc12 +CCOc1cccc(C(C)NC(=O)Nc2ccc(OC)c(OC)c2)c1 +CCn1c(C)cc(C(=O)NCCCC(N)=O)c1C +Cc1nc(C(C)(C)NC(=O)CC2CCOc3ccccc32)sc1C +CN(Cc1nc2c(cnn2C)c(=O)[nH]1)c1cccc2ccccc12 +CCCC1=C(C(=O)OCC)C(c2ccco2)n2nc(C)nc2N1 +Cc1csc(CCNCc2ccc(Cl)cc2Cl)n1 +CC(=O)c1cccc(OC(C)C(=O)NCc2cscn2)c1 +C=C(C)CN1C(=O)C(C)Oc2c(OCCC)cc(CO)cc21 +Cn1cc(CNC(=O)N2CCN(c3ccccc3Cl)CC2)cn1 +O=C(CCn1nc2ccccn2c1=O)NCC(=O)Nc1cccnc1 +CC(C)(CNC(=O)c1cc(-c2ccc(F)cc2)on1)c1ccncc1 +Cc1ccc(NC(=O)CCc2c(C)nn(C)c2C)c(Cl)c1 +CNS(=O)(=O)c1cc(NC(=O)c2ccn(C)c(=O)c2)ccc1C +CCCCNC(=O)Nc1ccc(NC(=O)C(C)C)cc1 +Cc1nc(SCC2CCCO2)c2ccccc2n1 +COCCCNC(=O)C1CC(=O)N(c2cc(C)ccc2OC)C1 +Cc1cncc(C(=O)N2CCN(C3CCc4ccccc4C3)CC2)c1 +O=C(NCc1cccc(C(F)(F)F)c1)c1cc(-c2cccnc2)on1 +Cc1cccc(-c2noc(CNC(=O)CC(C)C)n2)c1 +COc1ccc(-c2nnsc2C(=O)NCc2cccnc2)cc1 +NS(=O)(=O)c1ccc(CNC(=O)N2CCCCCC2)cc1 +Cc1cccc(C(O)c2ccc3c(c2)CC(=O)N3C)c1 +CCCc1ccc(C(NC(=O)COC)C(C)C)cc1 +N#Cc1ccc(NC(=O)c2cnn(-c3ccccc3)n2)cc1 +Cn1c2c(c(=O)n(C)c1=O)C(c1ccc(O)cc1)NC(=O)N2 +COCCNC(=O)c1nc(COc2ccc3c(c2)OCO3)no1 +COCC(O)CN(C)C(=O)C(C)(C)c1cccc(F)c1 +CC1CN(CCC(=O)Nc2cc(Cl)ccc2N)CCO1 +C=CCNC(=O)c1cccc(S(=O)(=O)N(C)C(C)C)c1 +CC(C)(C)C(=O)Cn1c(C(F)(F)F)nc2ccccc21 +CC(=O)Nc1cccc(Nc2nc3cc4c(cc3[nH]2)OCO4)c1 +COc1cc(C#N)ccc1OC(=O)c1ccc(OCC(F)F)nc1 +O=C1C(=O)N(Cc2ccccn2)c2cc(F)ccc21 +CCCC1=C(C(=O)OC(C)C)C(c2cccnc2)NC(=O)N1C +CC(=O)Nc1cccc2c1nnn2C1OC(CO)C(O)C(O)C1O +Cc1n[nH]c(C)c1CNC(=O)Nc1cccc(C#N)c1 +Cc1noc(C)c1S(=O)(=O)N1CCC2(CCCN(C)C2=O)C1 +C=CC(CC(=O)N(C)c1ncccc1F)c1ccccc1 +Cc1ccc2c(c1)C(O)(CC(=O)c1ccccc1Cl)C(=O)N2 +COC(=O)Cn1c(C(C)(C)C)nc2ccc(F)c(F)c21 +COc1ccccc1NC1CCN(C(=O)c2ccco2)CC1 +O=C(Cc1ccccc1Cl)N1CCc2sccc2C1 +CCS(=O)(=O)c1ccc(NC(=O)c2cc3ccccc3o2)cc1 +CC1=C(C(=O)OCc2ccccc2)C(c2ccco2)NC(=O)N1 +COc1ccc(NC(=O)NCCCC(N)=O)cc1OC +Cc1nc(CCC(=O)OC(C)c2ccccn2)oc1-c1ccccc1 +COC(CNC(=O)c1cc(C2CC2)on1)c1ccsc1 +COc1ccc(OC)c(C(=O)NC(C)c2nc(C)no2)c1 +Cc1nn2c(=O)c(CCO)c(C)[nH]c2c1-c1ccc(F)cc1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)N(CC(C)C)CC(C)C +CCc1nnc(-c2ccc(NC(=O)N3CCC(O)C3)cc2)o1 +CC1CC(N2CCOC(c3nc(C(C)C)n[nH]3)C2)C(=O)O1 +COc1ccc(OC)c(N(C(C)C(N)=O)S(C)(=O)=O)c1 +Cn1ccsc1=NC(=O)c1ccc(F)c(F)c1F +Cc1ccc(NC(=O)CN(C)C(=O)c2ccccn2)cc1 +CC(C)OC(=O)CC1NC2CCCCC2NC1=O +CN1C(=O)c2c(sc3c2CC(C)(C)OC3)N2CCCN=C12 +COCCCNC(=O)COc1cc(C)cc2oc(=O)cc(C)c12 +Cc1cc(C(=O)N2CCCC2)ccc1NC(=O)N(C)CCO +Cc1ccc(C)c2c(C)c(C(=O)N(C)C3COCC3O)[nH]c12 +CN(C(=O)C1CCC(=O)N1)c1ccc2ccccc2c1 +CN(C)C(CNC(=O)NCc1ncn(C)n1)c1c(F)cccc1F +CCOCCCn1ccnc1-c1nc2ccccc2[nH]1 +Cc1ccc(C)c(S(=O)(=O)CC(=O)N(C2CC2)C(C)C2CC2)c1 +COc1ccc2c(C(=O)N(C)C)cc(-c3cnc(N)nc3)nc2c1 +COc1cc(CN(C)C(=O)c2cc(C)no2)c(SC)cc1OC +CCS(=O)(=O)c1ccc(NCc2ccc(C)s2)cc1 +Cc1ccc(C(O)(CCNC(=O)c2sccc2C)C(F)(F)F)o1 +CN(Cc1ccsc1)C(=O)Cn1nnn(-c2cccs2)c1=O +CCC(CC1CCCCC1)C(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1cc2[nH]c(=O)[nH]c2cc1NC(=O)c1ccco1 +OCCc1c[nH]c2ccc(Oc3ccccc3)cc12 +Cc1ccc2nc(C(=O)N(C)Cc3cc(C4CC4)on3)cn2c1 +CCOc1ccc(C(=O)NCC(=O)N(CC)CC)cc1 +COCCCNC(=O)N1CCC2(C1)C(=O)Nc1ccc(OC)cc12 +O=C(NC(c1ccncc1)c1ccc(Cl)cc1)C1CCCO1 +Cn1c(=O)c(=O)[nH]c2cc(-c3noc(C4CC4)n3)ccc21 +CCN(CC)S(=O)(=O)c1cccc(C(=O)C(C)C)c1 +Cc1cc(C(=O)N2CCCCC2CCO)c2ccc(C)c(C)c2n1 +O=C(C(O)Cc1cccc(Br)c1)N1CCNCC1 +COc1ccc(OC)c(C(=O)CSc2nc3ncccc3[nH]2)c1 +CC(C)(C)c1cc(NC(=O)CN2CCN(C(=O)CO)CC2)on1 +Cc1n[nH]c(C)c1CCC(=O)NCCc1nc2ccccc2[nH]1 +CN1CCOC(CNc2ncnc3ccccc23)C1 +COc1ccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)c(OC)c1 +CN(C)S(=O)(=O)c1cccc(C(=O)NCCO)c1 +Cc1noc(Cc2ccccc2NC(=O)c2ccc(=O)n(C)n2)n1 +COc1ccccc1C(C#N)N(C)C(=O)OC(C)(C)C +Cc1cccc(NC(=O)c2nn(C)c3ccccc3c2=O)n1 +COc1ccc(Cl)cc1C(=O)n1nc(C)cc1C +C=CCN1CCC2CN(c3cnccn3)CC2C1=O +COc1ccc(S(=O)(=O)NCc2cnn(C)c2)cc1F +Nc1ccccc1Cc1nccn1Cc1ccccc1 +COc1ccsc1S(=O)(=O)N1CC(CO)CCC1C +COCCNC(=O)Nc1ccc(Cn2cccn2)cc1 +CCCc1n[nH]c(C2CN(CC(=O)NCc3ccccn3)CCO2)n1 +C#CCN1CCN(C(C)C(=O)NC(C)c2ccc(F)cc2)CC1 +COc1ccccc1-c1noc(COC(=O)c2c(C)noc2C)n1 +CSc1nccc(OC2CCCN(C(=O)OC(C)(C)C)C2)n1 +COc1ccc(-n2cnnc2SCc2nnc(C3CC3)o2)cn1 +N#CC(NC(=O)CNC(=O)c1ccc2c(c1)CCC2)C1CC1 +COc1cc(OC)c(NC(=O)COc2ccccc2C)cc1F +CCCOc1cc2c(cc1OC)CCNC2c1ccc[nH]1 +CC(C)C(O)c1ccc2c(c1)CN(C(=O)C(C)(C)C)CC2 +Fc1ccc2c(Br)cnc(N3CCCC3)c2c1 +Nc1cccc(-c2nc3cc(F)ccc3n2C2CC2)c1 +CC1CN(Cc2cccc(NC(=O)C(C)(C)C)c2)CC(C)O1 +CCNC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +CCCn1c(=O)c2nscc2n(CC(=O)NC(C)C)c1=O +CC(C)c1nnc(NC(=O)CCc2ccccn2)s1 +CC(C)(C)c1cc(NC(=O)Cc2ccccc2)no1 +Cc1cc(C(=O)Nc2ccc(C)c(Cl)c2)c(C)o1 +Cc1cc(C(=O)Nc2cc(F)cc(N3CCCC3)c2)[nH]n1 +CCOc1cc(C)nc(N2CCN(C(=O)c3ccnn3C)CC2)n1 +C=CCN1CCN(C)C(=O)C12CCN(C(=O)CCOC)C2 +O=S(=O)(c1ccccc1F)N(CCO)Cc1ccccc1 +Cc1ccc(C(C)NC(=O)c2cccc(N3CCCC3=O)c2)cc1F +CC(C)CCNC(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1 +O=C(NCc1cnn(Cc2ccccc2)c1)C1CC1(Cl)Cl +COC(=O)C1c2ccsc2CCN1C(=O)CC1CCCC1 +O=C1CCc2cc(OCC(=O)NC3CCCCC3)ccc2N1 +NC(=O)c1ccc(Nc2nc(N)nc3[nH]cnc23)cc1 +CCCOc1ccc(CNC(=O)c2ccn(C)c(=O)c2)cc1OC +CCC(C)NC(=O)NC(C)c1cc(F)ccc1F +Cc1nc2cc(-c3noc(-c4ccco4)n3)ccc2n(C)c1=O +Cn1cc(N2CCCC(Nc3cnn(C)c(=O)c3Cl)C2)cn1 +Cc1nc(CNC(=O)COCC2CCCO2)oc1C +OCCn1ccc(-c2ccccc2OCc2ccc(F)cc2)n1 +CCn1cc(-c2nnc(SCC(=O)Nc3ccccc3)n2C)cn1 +CC(C)CCNC(=O)C(C)NC(C)c1ccc(F)c(F)c1 +CCOC(=O)NCCC(=O)NC1CCC(CC)CC1 +CC(C)OCCCNC(=O)c1onc(-c2ccccc2)c1N +Cc1ccc(OCC(=O)OCc2cc(=O)n3c(C)csc3n2)cc1 +Cn1ncc(C(=O)OCCc2cccnc2)c1-n1cccc1 +CNc1nc(-c2ccc3oc(=O)n(C)c3c2)cs1 +CCc1cnc(CCNC(=O)N2CCC(N(C)C(C)=O)CC2)s1 +NC(=O)Nc1cccc(Cn2nc3ccccn3c2=O)c1 +CC(=O)Nc1cccc2c1CCN(c1cc(=O)n3ccccc3n1)C2 +Cc1ccc(N2CC(C(=O)Nc3ccc(F)cn3)CCC2=O)cc1C +CC(C)Oc1ccccc1NC(=O)C1CCCN(C(N)=O)C1 +CCCCNC(=O)CNC(=O)c1cc(C)nn1CC +CC(=O)N1CCC(NC(=O)c2sccc2-n2cccc2)CC1 +CCN(C(=O)c1snc(C(=O)OC)c1N)c1ccccc1 +Cc1cc2c(c(C(O)C3CCCCC3)c1)NC(=O)CC2 +CCOc1ccc(C(=O)CN2CC(C)OC(C)C2)c(C)c1C +CCCS(=O)(=O)NCc1cn2ccccc2n1 +Cc1ccc(C(=O)NCc2nnc(C3CCC3)n2C)s1 +O=C(NC1CCCc2ccccc21)c1cncn1-c1ccccc1 +O=C(Cn1cccnc1=O)Nc1cccc(F)c1F +COc1ccc(OC)c(NC(=O)Oc2ccc(NC(C)=O)cc2)c1 +Cc1csc(CNc2ccccc2SCC(C)C#N)n1 +COC(=O)c1cc(-c2ccc(Cl)cc2)n(C(=O)OC)n1 +Cc1nnc(SCC(=O)NC2CCCCC2)[nH]1 +Cc1cc(C(=O)Nc2nc3cc4c(cc3s2)OCCCO4)on1 +CC(=O)c1nnn(-c2cccc(Br)c2)c1C +CC(C)(C)c1ncsc1NC(=O)c1cnc(C2CC2)s1 +O=C(NCc1nnnn1-c1ccccc1)Nc1cccc(Cl)c1 +CN(C)c1cccc(OCCN2C(=O)Cc3ccccc32)c1 +CCC1CN(C(=O)C2CC(=O)N(C3CC3)C2)CC1N1CCOCC1 +CCN(CC)C(=O)c1cnc(CCOC)nc1N +COc1ccc2c(c1)CC(C(=O)Nc1ccccc1F)CO2 +O=C(Cc1ccc(-n2cccn2)cc1)NCC(F)(F)F +COCCS(=O)(=O)c1ccc(C(=O)NC2CCC(C)CC2)cc1 +COc1ccc(C(O)CNc2cc(C)ccc2C)cc1OC +O=S(=O)(c1cccnc1)N1CCN(CC(O)c2ccco2)CC1 +CCOC(=O)C(NCC(F)(F)F)c1ccc(C)cc1 +Clc1ccc(-n2ncc3c2ncn2nc(-c4ccco4)nc32)cc1 +CCN(CCC#N)C(=O)CSc1cccc(C(F)(F)F)c1 +CC(C)C1(CNC(=O)c2cccc(OCC(F)F)n2)CC1 +CC(=O)N1CCc2cc(-c3csc(NC(=O)C(C)C)n3)ccc21 +Cc1ccc2c(c1F)C(c1cnn3ccccc13)NCC2 +Cc1cc(-c2nnc(SCC(=O)Nc3ccc(C)c(F)c3)o2)no1 +COC(=O)Cn1cnc2scc(-c3ccc(C)c(C)c3)c2c1=O +COC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)c2c(C)noc2C)c1C +O=C(Cc1noc(-c2n[nH]c(=O)c3ccccc23)n1)Nc1ccccc1 +NC(=O)c1ccc(NC(=O)NC2CC2c2cccc(Cl)c2)cc1F +COc1ccc(CC2CCN(C(=O)c3cc(C)no3)CC2)cc1 +CCCCN(C)S(=O)(=O)N1CCCc2cc(OC)ccc21 +O=C(CCCNC(=O)c1cc2ccoc2s1)Nc1cccnc1 +CCOc1ncnc2c1CN(C(C)C(=O)Nc1cc(C)on1)CC2 +O=C(Cn1cnnn1)NCC(O)c1cc(Cl)cc(Cl)c1 +COCCN1CC(C(=O)Nc2ccc3oc(=O)ccc3c2)CC1=O +CC(=O)N1CCc2cc(S(=O)(=O)NCCc3ccco3)ccc21 +Nc1c(Br)c(=O)[nH]c(=O)n1Cc1ccccc1 +O=C(NCCCO)NCCNC(=O)c1ccccc1Cl +CC(C)(C)CNS(=O)(=O)C1CS(=O)(=O)c2ccccc21 +Cc1nc2c(s1)C(N(C)C(=O)Nc1nccn(C)c1=O)CCC2 +COc1ccc(CC(=O)N2CCOC3C(OC)CCC32)c(OC)c1 +Cc1noc(C)c1C(C)NC(=O)N(Cc1cccnc1)C(C)C +C#CCNC(=O)CCNC(=O)C1(c2ccc(F)cc2)CC1 +Cc1nc2ccc(C(=O)NCc3ccc4c(c3)OCO4)cc2nc1C +CCC(CC)c1nnc(NC(=O)Cc2c(F)cccc2F)s1 +COc1ccc(OC)c(NC(=O)CNC(=O)c2ccccc2OC)c1 +O=C(C1COc2ccccc2O1)N1CCSc2ncccc21 +CCCc1nc2c(s1)CN(Cc1cccc(C#N)c1)CC2 +CC(C#N)(NC(=O)COc1cc(Cl)ccc1Cl)C1CC1 +COc1ccc(OC)c(-n2cnnc2Cc2nc(C)cs2)c1 +Cc1ccc(OCCNC(=O)c2ccncc2)cc1 +N#CCCSc1nnc(-c2ccc(Cl)cc2)o1 +CC1CCC(NC(=O)CN(CCC(N)=O)c2ccc(F)cc2)CC1 +CSc1n[nH]c2ncnc(N3CCN(c4ccccc4)CC3)c12 +O=C(Cn1cnc2ccsc2c1=O)NCC1(c2ccccc2)CC1 +N#Cc1cccc(NC(=O)NCC2CN3CCCCC3CO2)c1 +COc1cccc(C(=O)OCC(=O)Nc2ccc(C)cc2)c1F +Cc1ccccc1Cn1cc(NC(=O)c2cc3ccccn3n2)cn1 +Cc1ccc(CN2CCOC(CCNS(C)(=O)=O)C2)cc1C +Cc1ccc(NC(=O)CSc2nn3cnnc3o2)cc1F +COC(=O)C1(C)CC1(Br)Br +CCn1ncc(C(=O)NCCSc2nc3ccccc3o2)c1C +Cc1ccccc1Oc1ccc(S(=O)(=O)N2CCCC2)cn1 +COc1ccc2ncc(NC(=O)NCCc3ccco3)c(O)c2n1 +CCC(C)N(C)C(=O)c1ccc2c(c1)CCCN2S(C)(=O)=O +N#Cc1ccc(-n2c(C#N)nc3cccc(F)c32)nc1 +Cc1nn(C)c(C)c1C(=O)OC(C)c1ccc2c(c1)OCCO2 +Cc1cc(Br)ccc1C(=O)NCCNc1ncccn1 +COc1ccc(OC)c(CNC(=O)c2cnc(SC)nc2C)c1 +CCCN(CC(=O)OCC)C(=O)c1cnc2ccc(C)cn12 +Nc1ccc2[nH]nc(-c3cccc(CN4CCOCC4)c3)c2c1 +CCOc1ccccc1OCCN1CCCCS1(=O)=O +C#CCNC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1Cl +Cc1cccc(N2C(=O)CCC2(C)C(=O)NCCC(C)C)c1C +CN(C(=O)c1cc(C(N)=O)cn1C)C1CCCCCC1 +CC(C)C(Nc1cc(C#N)ccn1)c1cccs1 +Cc1nc2ccccc2nc1CN1CC2(CCCC2)CC1=O +Cc1oc2ncn(C)c(=O)c2c1C(=O)NCCN1CCOCC1 +O=C(Nc1cnn(-c2ncncc2N2CCCCC2)c1)c1ccco1 +O=S(=O)(NCc1ccc(-n2cncn2)nc1)N1CCCCC1 +CC(C)NS(=O)(=O)c1ccc2c(c1)nc(-c1ncc[nH]1)n2C(C)C +O=C(Nc1ccccc1O)c1ccc2c(c1)OCO2 +O=C(c1cccc(-n2cncn2)c1)N1CCC(Cc2ccccc2)C1 +CC(C(=O)OC(C)(C)C)N(C)Cc1ccccn1 +Cc1noc(C)c1C(C)NC(=O)c1nc(-c2ccco2)sc1C +CC(C)(CNC(=O)c1ccccc1OC(F)F)N1CCOCC1 +Cc1csc(SCc2cn3c(C)cccc3n2)n1 +Cn1nnnc1SCC(=O)Nc1ccc2ccccc2c1 +CC(NC(=O)c1ccc[nH]c1=O)c1cccc(C(F)(F)F)c1 +COC(=O)c1cc(C)nc2c1c(=O)[nH]c(=O)n2-c1ccccc1 +O=c1[nH]n(-c2ccc(Br)cc2)c(=O)c2cccnc12 +COc1ccc(C(=O)Nc2ccc3cnn(C)c3c2)c(N)c1 +COc1ccc(OCC(=O)Nc2ccccc2C(=O)NC2CC2)cc1 +Cc1nc(C(=O)N2CCOC3CCCCC32)ccc1C#N +O=C(NCCc1ccco1)c1ccc2ncsc2c1 +CC(C)C(C)NC(=O)CS(=O)(=O)c1nnc(C2CC2)n1C +CCc1onc(C)c1NC(=O)N1CCCC1C(=O)NC +CS(=O)(=O)c1ccc(C#N)cc1NC(=O)COc1ccc(F)cc1 +Cc1cc(NC(=O)Cn2cnnn2)ncc1Br +Cc1sc2ncnc(N3CCN(CC(C)O)C(C)C3)c2c1C +Cc1noc(C(C)NC(=O)c2cccc(-n3ccnn3)c2)n1 +O=C(CCc1nc(C2CCOC2)no1)c1ccccc1 +C#CCNC(=O)COc1ccc(N2CCCC2=O)cc1 +CCOC(=O)c1c(C)oc(N)c1-c1nc2ccccc2[nH]1 +Cc1cccc(NS(=O)(=O)c2cn[nH]c2C)c1 +O=C(c1ccc2cnn(Cc3cccc(F)c3)c2c1)N1CCOCC1 +Fc1ccc(NCc2noc(C3COc4ccccc4O3)n2)cc1F +CNc1nc(CNC(=O)Nc2ccc(C(N)=O)c(C)c2)cs1 +c1ccc(CN2CCOC(c3nc(-c4ccccc4)cs3)C2)cc1 +COCC(c1cccc(C(F)(F)F)c1)N(C)Cc1nnc(C)o1 +COc1cccc(NC(=O)COc2ccc(C(=O)N(C)C)cc2)c1 +COc1ccc(-c2cnc(N3CCC(O)CC3)nc2)cc1 +CC(C(=O)N1CCc2sccc2C1)n1cccn1 +COc1cc(-c2ncc(CO)s2)ccc1OCC(C)C +CC(O)c1ccc(NC(=O)NCc2cn[nH]c2)cc1 +COc1ccc(CN(C)C(=O)c2ccc(Cl)cc2)cc1F +CC(NC(=O)N1CCN(Cc2ccncc2)CC1)C1CC1 +CC(=O)NCCNC(=O)Nc1ccc(-n2cnnn2)c(C)c1 +Cc1cccc(CNC(C#N)c2ccc3c(c2)OCCO3)c1 +Cc1ccc(-c2nn3c(=O)c(NC(=O)c4ccccc4)cnc3o2)cc1 +Cc1ncsc1C(=O)NCCOc1cccc(F)c1 +Cc1nc2nnc(-c3ccnc(Nc4ccccc4)n3)c(C)n2n1 +c1ccc(-n2cc(-c3ccnc(NC4CCC4)n3)cn2)cc1 +COc1cc(C(=O)NCc2ccc(F)cc2)ccc1OC(F)F +Cc1noc(COCC(=O)NC(C)c2ccccc2Cl)n1 +C#CCNC(=O)c1nn(CC)c(=O)c2ccccc12 +CCCc1nn(-c2ccc(C(=O)OC)cc2)c2c1CNCC2 +O=c1cc(-c2ccncc2)nc(C2CCCN(Cc3cccnc3)C2)[nH]1 +CC(C)(C)c1nc(-c2ccc(F)c(Br)c2)c(N)n1N +CC(=O)Nc1nc(-c2ccc3c(c2)NC(=O)C(C)O3)cs1 +COc1ccc(F)cc1C(O)Cn1cc(N)cn1 +CN(Cc1ccc(O)cc1)C(=O)c1csc(-c2ccco2)n1 +CC(=O)NCC(=O)N1CCC(Oc2cccc(Cl)c2)C1 +Cc1ncc(CO)c2cc(C(=O)c3ccc(Br)cc3)oc12 +Nc1ccccc1Cc1nccn1Cc1ccc(F)cc1F +Cc1cccn2c(=O)c(-c3nc(CCc4ccccc4)no3)cnc12 +COCC1COCCC12CCN(C(=O)c1cccnc1OC)CC2 +CCN(Cc1nc2c(c(=O)[nH]c(=O)n2C)n1C)c1cc(C)cc(C)c1 +COC(=O)c1ccc(CNC(=O)CSc2ccccc2)cc1 +NC(=O)C1CCN(C(=O)Cn2cnc3ccccc32)CC1 +Cc1cccc(CNC(=O)N2CCCN(c3nc(C)cs3)CC2)c1 +O=C(CCc1ccco1)N1CCCC1c1ccc2c(c1)OCCO2 +COc1cccc(C(=O)c2c(N)oc3c2CCCC3)c1 +NC(=O)c1ccc(COC(=O)c2cnn(Cc3ccccc3)c2)cc1 +CCOC(=O)CNC(=O)NC(C)c1ccc(C)s1 +COc1ccc(-n2cnnc2SCC(=O)NC2CCCC2)cc1 +CCC(C)(CC)NC(=O)c1scnc1C1CC1 +COCCN(Cc1ccccc1)S(=O)(=O)c1cc(F)ccc1C +CC(C)CNC(=O)c1c2ccccc2n2ccsc12 +CCn1ncc(Cl)c1CNC(=O)c1cc(C)nc2onc(C)c12 +Cc1cc(C)cc(-n2ncc3c(=O)n(CC(C#N)CCC#N)cnc32)c1 +CCNC(=O)c1cnn(-c2ccc(Cl)cc2)c1C(C)C +Cc1ccc(-n2ncc(C(=O)NC(C)(C)C)c2-n2cccc2)cc1 +COc1ccc(NC(=O)N(C)CCC#N)cc1N1CCCC1=O +Cc1cccc2nc(C(=O)c3c(-c4ccncc4)[nH]n(C)c3=O)cn12 +COc1ccc(-c2cc(O)cc(C)c2N)c(OC)c1OC +Clc1ccc(-n2nc(C3CC3)nc2-c2cccnn2)cc1 +COc1ccc(-c2n[nH]cc2C(=O)NCc2ccc(C)cc2)cc1 +CCC(C)C(C)NS(=O)(=O)Cc1ccccc1 +CNc1ncc(S(=O)(=O)NC2CCCC2)cc1Cl +COc1ccc(C(CC(=O)N2CCCC2)NC(C)=O)cc1 +CCOC(=O)CC(C)CNC(=O)N1CCc2ccccc2CC1 +Cc1ccc(SCC(=O)N(C)CC(N)=O)cc1 +O=C(C1CCCC1)N1CCCC(c2nc3ccccc3[nH]2)C1 +Cc1ccc(NC(=O)CCC(C#N)c2ccco2)cc1C +Cc1nc2ccccc2n1CC(O)c1cccc(F)c1 +CC(O)CN1CCN(C(=O)c2cccn2Cc2cccnc2)CC1 +CCOc1ccc(CN(C)C(=O)c2cccc(OC)c2OC)cc1 +COCCC(NC(=O)OC(C)(C)C)c1ccco1 +CCCS(=O)(=O)N1CCCC1C(=O)Nc1cc(OC)ccc1F +CC(=O)N1CCN(C(=O)CSc2ccnc3ccccc23)CC1 +O=C(c1cnccn1)N1CCC(c2ccccc2)C1 +COc1cccc(C(=O)CN2CCN(c3ccc(F)cc3)CC2)c1 +C=CCn1c(=O)c2c(nc3n(-c4ccccc4C)c(C)cn23)n(C)c1=O +O=C(COC(=O)CNC(=O)c1ccco1)Nc1ccc(F)cc1 +CCn1ccnc1SCC(=O)Nc1cc(C)nn1-c1ccccc1 +CCOc1c(Cl)cc(C(=O)Nc2cc(C)on2)cc1OC +CC(CNC(=O)Cc1ccc[nH]1)CN1CCOCC1 +CC1CN(C(C)(C)CNC(=O)N2CCCCC2C)CC(C)O1 +COc1cc(N)c(CCC(=O)N2CCCC2)cc1OC +Cc1cc(OCc2ncc(CO)s2)cc(C)c1Cl +CCc1cc(C(=O)N2CCC3(CC(=O)c4ccccc4O3)C2)on1 +Nc1ccccc1C(=O)OCC(=O)Nc1ccccc1C(F)(F)F +CCOc1ccccc1NC(=O)CCc1ccccn1 +CC(C)CC(CNC(=O)Nn1cnc2ccccc21)N1CCOCC1 +CCC(CC)NS(=O)(=O)c1ccc(C)c2c1CCCN2 +Cc1cc(C(=O)OC(C(=O)NC2CC2)c2ccccc2)c(C)s1 +COC(=O)C1CCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1 +Cc1cccc(-c2nnc(SCC(=O)NC(C)C(C)C)n2C)c1 +COCCC(C)C(=O)Nc1cc(F)ccc1OC +OC(CNc1cc(Br)ccc1Cl)Cn1cccn1 +CCN(CC)C(=O)Cn1nc2cc(-c3ccccc3)nc(C)n2c1=O +CCN(C(=O)C(O)c1ccc(C)c(C)c1)c1ccccc1 +CCSc1ccccc1C(=O)Nc1nnc2n1CCS2 +COC(=O)c1ccc(CN2CCc3ccc(Cl)cc3C2)o1 +COC(=O)c1cc(CNC(=O)c2cc3c(s2)CCC3)oc1C +C=CCn1cc(C(=O)Nc2c[nH]ccc2=O)c2ccccc21 +CCCCc1noc(C(C)Nc2ccc3[nH]c(=O)[nH]c3c2)n1 +CCNC(=O)CNc1ccc(NC(C)=O)cc1C(F)(F)F +O=C(CCc1nc2ccc(F)cc2[nH]1)NCC1(O)CCCCC1 +Cc1nc(CNC(=O)N2CCCc3c(F)cc(F)cc32)cs1 +Cn1ncc2c(=O)[nH]c(NCc3ccccc3Oc3ccccc3)nc21 +Cc1ccc(Cl)cc1NC(=O)NCc1ccncc1 +CCOc1cccc(CC(=O)Nc2ccc3c(c2)COC3)c1 +Cc1nnc(C(C)N2CCOC(c3ccccc3C(F)(F)F)C2)o1 +Cn1cc(N2CCC(Nc3nc(-c4ccccc4)cs3)C2=O)cn1 +O=C(NC(N1CCCC1)C(Cl)(Cl)Cl)c1ccccc1 +CCCn1cc(C(=O)N2CCCC(C)C2)c(=O)c2c(N)cccc21 +CC(C)NC(=O)c1nc2cc(C(F)(F)F)ccc2n1C +CCN1CC2(CCN(C(=O)c3ccc(C)cn3)CC2)C(COC)C1=O +N#Cc1ccc(NC(=O)Cc2ccccc2Cl)nc1 +O=C(c1ccc[nH]1)N1CCc2ncnc(NC3CCC3)c2CC1 +Cc1cc(NC(=O)c2cc(F)cc(F)c2)ccc1S(N)(=O)=O +Nc1ccc2c(c1)CCN2C(=O)c1cccc(O)c1 +COC(=O)c1c(C2Nc3ccccc3O2)ccc(OC)c1OC +CC(Cc1nc(-c2ccc(C#N)cn2)no1)C(C)(C)C +O=C(NCc1ccc(Br)cc1)NCC1COCCO1 +CC1(C)COCCN1CCNc1ccccc1Br +Cc1cnccc1CCNC(=O)Nc1cccc(-n2ccnn2)c1 +O=C(NCc1ccc(Cn2ccnc2)cc1)NCc1ccccn1 +Cc1cc(C(=O)NCC(C)(C)c2ccncc2)ccc1S(N)(=O)=O +COCCn1nc(C)c(CNC(=O)N2CCC(C(C)C)CC2)c1C +Cc1nn(CC(C)C)c(C)c1S(=O)(=O)NCCn1ccnc1 +Cc1ccccc1OCCN1C(=O)Cc2ccccc21 +CC(=O)c1cccc(NC(=O)C(C)Nc2cnn(C(C)(C)C)c2)c1 +Cc1ccc(C(=O)N2CCC3(CC(=O)c4ccccc4O3)C2)c(C)c1 +Cc1ccc(C(=O)N2CCC(C)Sc3ccccc32)cn1 +Cn1c(=O)c2c(ncn2Cc2cccnc2)n(C)c1=O +COC(=O)C1CCCC1NC(=O)Nc1ccc(-n2ccnn2)cc1 +Cc1cc2c(=O)n(Cc3nc4cc(F)ccc4o3)cnc2s1 +CCn1nccc1C(=O)Nc1cnn(Cc2c(F)cccc2Cl)c1 +CC(C)C(NS(=O)(=O)c1ccccc1)C(N)=O +CN(Cc1cccc(F)c1)C(=O)CSc1ccccc1 +CCCc1ccc(-c2nccn2CC2CN(C(C)=O)CCO2)o1 +C=CCn1c(SCC(=O)OCC)nc2sccc2c1=O +CN(Cc1cccnc1)C(=O)COc1cccc2c1OC(C)(C)C2 +CCc1ccc(S(=O)(=O)NCC#CCOc2ccc(C)nc2)cc1 +CCc1noc(C)c1NC(=O)N1CC(C)CCC1C +COc1ccc(CSc2n[nH]c(N)n2)c(Br)c1OC +COc1ccc(Br)cc1Cn1nc(C)nc1C +COc1ccc(CC(=O)Nc2cccc(N)c2C)cc1 +Cc1ccc(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)nc1 +Cc1ccccc1OC(C)C(=O)N1CCN(Cc2ccccc2)CC1 +COCC(C)NC(=O)N1CCN(c2ncnc3sccc23)CC1 +Cn1cc(C(=O)NCCc2ccccc2)c(-c2ccc(F)cc2F)n1 +CCc1ccc(-c2ccc(N)c(=O)n2CC2CCCO2)cc1 +CCCOc1c(C#N)c(C#N)c2nc(C)cc(C)n12 +c1cnc(N2CC3OCCN(CC4CCCO4)C3C2)cn1 +COc1ccc2[nH]c(C(=O)NCCc3ccccn3)cc2c1 +CCc1ccc(C(=O)Nc2nc(C)c(C(C)=O)s2)cc1 +Cc1cc(NC(=O)c2cc(C)on2)n(-c2nc3ccccc3s2)n1 +Cc1cccn2c(CN3CCN(Cc4ccncc4)CC3)cnc12 +COc1ccc(NC(=O)CCC(=O)c2cc(C)sc2C)c(OC)c1 +COCc1cc(C)nc2c1C1=NC(c3ccccc3)=NC(=O)C1S2 +COC(=O)Cn1c(=O)c2c3c(sc2n(C)c1=O)COC(C)(C)C3 +N#Cc1cc(N)cnc1Oc1ccc(Br)cc1 +O=C(NCCCc1nc2ccccc2[nH]1)c1cc(-c2ccccc2)[nH]n1 +C#CCn1c(=O)c(-c2ccccc2)nc2ccc(N)cc21 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1ccc(F)c(F)c1 +Cc1noc(C)c1CNc1ccn(-c2ncccc2Cl)n1 +O=C(Cc1ccccc1F)NC1CCN(C(=O)C2CCCCC2)CC1 +Cc1ccsc1-c1nc(CN2CCNC(=O)C2C)c(C)o1 +CC1CCCN(c2c(C#N)c(=O)n(C)c(=O)n2C)CC1 +COc1cccc(C2CCN(C(=O)c3cnc(C)nc3C)C2)c1OC +Cn1cc(CN2CCN3C(=O)C(=O)NCC3C2)c(-c2cccs2)n1 +Cc1nn(C)c(C)c1C(C)NC(=O)NCC1CCCO1 +CCCS(=O)(=O)c1ccc(C)cc1-c1cc(C(=O)OC)no1 +COc1ccc(C2Nc3ccccc3C(=O)N2C(C)C)cc1OC +CCC(=O)Nc1cccc(NC(=O)C2CCCC2)c1C +Cc1c(O)ccc2c(=O)c(-c3nncn3-c3ccccc3)coc12 +CC(NC(=O)CNC(=O)OCc1ccccc1)c1ccncc1 +O=C(Nc1cccc(C(=O)NC2CC2)c1)c1ccc2c(c1)CCC2 +Cn1ccsc1=NC(=O)Cc1cccc(OCC#N)c1 +CNC(=O)c1ccc(C2CN(Cc3ccc(F)cc3)CCO2)nc1 +CC1CC(c2ccc(F)cc2)CN1C(=O)c1ccc(C#N)cn1 +Cc1ccc(CC(=O)Nc2cccnc2N(C)C)cn1 +CN(Cc1ccn[nH]1)C(=O)CCNC(=O)c1ccccc1F +CC(C)Cn1ncc(C(=O)Nc2ccnn2C)c1C1CC1 +CCCNC(=O)CCC(=O)N1CCc2cc(Br)ccc21 +COc1ccc(O)cc1-c1nccn1Cc1cccc(-n2cccn2)c1 +CCN1CCOC(C(=O)NC2CCN(c3ccc(F)cc3F)C2)C1 +O=C(NCC(O)C1CC1)Nc1ccc(F)cc1OCC(F)(F)F +CCn1nccc1NC(=O)NC1CC2(CCCC2)Oc2ccccc21 +CCNC(=O)c1cc2cnn(C(C)C(C)C)c2nc1N +COc1cc(NC(=O)c2ccc3c(c2)CCC3)c(C(N)=O)cc1OC +Cc1[nH]nc2c1NC(c1ccc(OC(C)C#N)cc1)NC2=O +Cn1cncc1COC(=O)c1nc(-c2ccccc2)oc1C1CC1 +Cc1cc(C(=O)NCCO)nc(N2CCCCCC2)n1 +CC(NC(=O)C(C)(C)C)c1nc(-c2ccsc2)no1 +O=C(c1c[nH]c2ccccc12)N1CCC(Oc2cccnc2)CC1 +COCCNS(=O)(=O)c1ccc(OC)c(C(C)(C)C)c1 +CCC(C)NS(=O)(=O)c1cc(OC)ccc1OC +CC(C)Cn1c(SCCO)nnc1-c1ccco1 +COc1ccc(C(=O)Nc2cc(C)on2)cc1OC(F)F +Cc1ccc(OCC(=O)Nc2noc(-c3ccc(F)cc3)n2)cc1 +CCN(C(=O)C1CN(C(C)=O)c2ccccc2O1)C(C)COC +CC(C#N)NC(=O)CCn1c(=O)oc2ccccc21 +COCCNC(=O)Nc1ccc(-c2nc(C(C)C)no2)cc1 +CC(C)c1noc(CCCC(=O)N(C)C2CCc3ccccc3C2)n1 +CCN1CCN(C(=O)Nc2ccccc2OC)c2cccnc21 +CCc1cccc(C)c1NC(=O)Oc1ccc(C#N)cc1 +CCC(C)n1ncc(C(=O)NC2C3CCOC3C2(C)C)c1C1CC1 +O=C(NCc1ncc[nH]1)c1cn(-c2ccc(Br)cc2)cn1 +CCCC(O)(CCC)CNC(=O)c1oc2c(c1C)C(=O)CCC2 +Cc1cnc(NC(=O)CCCc2nnc(-c3ccccc3)o2)s1 +CCc1ccc(CC)c(C(=O)Cn2c(=O)c(C#N)cn(C)c2=O)c1 +Cc1nnc(C)c2c(C)n(-c3ccccc3N)c(C)c12 +Cc1ccc(CNC(=O)COc2ccc3c(c2)CCC(=O)N3)cn1 +CC1CCCC(NC(=O)C(C)N2CCOC(C)(C)C2)C1C +CC(=O)N1CCc2cc(C(=O)N3CCCc4cccc(C)c43)ccc21 +CCC(NC(=O)c1n[nH]c2ccccc12)c1nc(-c2ccccc2)c[nH]1 +CC(C)c1c(C(=O)N2CCOCC2)cnn1-c1ccc(F)cc1 +COc1ccc(NC(=O)CN2CCOCC2C2CC2)cc1Cl +CCOC(C)c1noc(Cn2nnc(-c3ccccc3C)n2)n1 +COc1ccc(S(=O)(=O)N(C)C(=O)CCc2ccccc2)cc1 +CCOCC1CN(Cc2ccc(OC)cc2)Cc2cnn(C)c21 +Cc1ccsc1C(=O)N(C)Cc1ccc(C#N)cc1 +CC(C)(C)OC(=O)NCCCC(=O)Nc1ccc(F)c(F)c1 +COc1c(C)cccc1Cn1nnc2ccccc21 +NC(=O)Nc1cccc(C(=O)OCC2CCCCO2)c1 +Nc1ccc2c(c1)OC(c1ccccc1)C(=O)N2Cc1ccc(F)cc1 +O=C(CSc1ncc2ccccn12)c1ccc2c(c1)OCO2 +CCc1c(C)[nH]c2c(OC)cc(Cl)c(OC)c2c1=O +CC(=O)NCC(=O)N1CCC(c2ccc3c(c2)OCO3)C(O)C1 +COCC(=O)NCCCc1nc2ccccc2n1C +CC1CCCC(NC(=O)c2ccc(S(=O)(=O)N(C)C)o2)C1 +Cc1cccn2c(NC(=O)c3ccco3)c(-c3cccs3)nc12 +Cn1nccc1CNC1(c2ccc(F)cc2F)CCOCC1 +CNC(=O)C(C)n1nc(-c2ccc(C)cc2)ccc1=O +O=c1ccn(Cc2cc(Br)cs2)c(=O)[nH]1 +O=C(CCC(=O)N1CCCCC1)c1ccc(F)c(F)c1 +Cc1cc(C(=O)NC2(C#N)CCCC2)c(C)n1-c1cccnc1 +COc1ccc2c(c1)ncn2Cc1ccccc1F +COC(=O)c1ccc(C(=O)OC)c(-n2cccc2)c1 +Cc1nn(-c2ccccc2)nc1C(=O)NC(c1cccs1)C(C)C +O=C(NCCCc1ccccc1)Nc1cc(N2CCOCC2)ncn1 +CC1CCCN(C(=O)COn2nnc3ccccc32)C1 +CCC(=O)N1CCc2cc(C(=O)NCc3cccs3)ccc21 +CC(C)Oc1cccc(C(=O)NCc2cc(=O)[nH]c3ccccc23)n1 +Cc1nc(C)n(CC(C)C(=O)N(C)Cc2sccc2C)n1 +O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc1cccc(F)c1 +CC(C)c1nnnn1CC(=O)Nc1ccc(F)cc1 +O=C(c1ccc(Cn2cccn2)o1)N1CC(c2ccncc2)C1 +CCc1nnc2n1CC(NCc1cnc(N3CCOCC3)nc1)CC2 +Nc1nc(=O)[nH]cc1Cc1c(F)cccc1Cl +Nc1ccc2nc(CC(=O)N3CCCCC3)ccc2c1 +COc1ccc(S(=O)(=O)Oc2ccc(F)cc2C(C)=O)cc1 +Cc1ccc2cc(CCNC(=O)c3ccccc3)c(=O)[nH]c2c1C +CC(=O)OCc1cc(-c2ccco2)n(-c2ncccc2Cl)n1 +CC1CN(CC(=O)c2ccc3c(c2)OCCO3)CC(C)O1 +CCc1noc(CC)c1CNC(=O)N1CCCC(C(=O)NC)C1 +Cc1ccc(C(=O)NCCc2csc(-n3cccn3)n2)cc1C +CC(C)(C(=O)N1CCN(c2cnccn2)CC1)c1ccc(Cl)cc1 +Cc1nc(CNC(=O)NC2(c3ccc(F)cc3F)CCCC2)oc1C +c1ccc(-c2cc(-c3nc(C4CC4)no3)[nH]n2)cc1 +NC(=O)CN(CCC1CCCCC1)c1ncnc2[nH]ncc12 +COCCOc1ccccc1NC(=O)c1n[nH]c2ccccc12 +CN(C)c1ncccc1N(C)C(=O)C1COc2ccc(F)cc2C1 +CCn1nc(C)c(NC(=O)c2c(Br)c(C)nn2C)c1C +CSc1ccc(CNS(=O)(=O)N2CCCCC2C)cc1 +O=C(NCc1ccc(Cn2ccnc2)cc1)C1CCCc2ccccc21 +CCSc1nnc(SCC(=O)N2CCC(C)CC2)s1 +NC(=O)C(Nc1cccc(N2CCCC2=O)c1)c1ccc(F)cc1 +CSc1ccccc1C(=O)NCC(O)c1ccsc1 +CCCNC(=O)Nc1ccc(NC(C)=O)c(OC)c1 +CCn1cnnc1C1CCN(C(=O)c2cnc3ccc(C)cn23)CC1 +CC(=O)N1CCN(Cc2cc(=O)c3cc(F)ccc3[nH]2)CC1 +CS(=O)(=O)N1CCC2C1CCN2Cc1cccnc1 +O=C(CNc1ccccc1C(=O)N1CCCCC1)N1CCCCC1 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)N1CCCC(O)C1 +Cc1ccccc1NC(=O)COC(=O)c1ccc2ccccc2n1 +CN(Cc1nccn1CC(F)(F)F)C(=O)c1cccc2ccccc12 +COCc1c(Br)cccc1NC(=O)c1cc(C)nn1C +C#CCCOC(=O)C(C)N1CCc2ccccc2C1 +Nc1cccn2nc(-c3ccc(-n4ccnc4)cc3)nc12 +COc1cc(OC)cc(C(=O)OCc2nc3ccccc3[nH]2)c1 +N#Cc1ncn(Cc2ccccc2Oc2cccnc2)n1 +CCOc1ccc(N2CCN(CC(=O)N(C)CCO)C2=O)cc1 +O=C(CSc1nncs1)c1sccc1Br +CCN1C(=O)Cc2cc(C(=O)N3CCCCC3)ccc21 +COc1cc(OC)c(C(=O)Nc2cccc(C)n2)cc1OC +C=CCNC(=O)C1CC(=O)N(c2ccccc2Cl)C1 +CCOc1ccc(F)c(C(=O)N(C)CCC2CC2)c1F +O=C(Nc1nc2c(C(F)(F)F)cccc2s1)c1ccccn1 +CC(C)C(Sc1nnc(Cc2cccs2)o1)C(=O)N(C)C +COCC(=O)N(Cc1ccc(OC2CCOC2)cc1)C1CCCC1 +COc1ncc(C2NCCc3ccc(C)cc32)c(OC)n1 +CCN(Cc1ccc(C(=O)NC)cc1)c1ccccc1 +O=C(Nc1cnn(CC2CCCO2)c1)NC1CCc2c(F)cccc21 +Cc1csc(C(C)(C)NC(=O)C(C)c2cccs2)n1 +COC(=O)C1(NS(=O)(=O)N(C)C)CCCC1 +COC(=O)c1sc(NC(=O)CSc2nnc(C)n2N)nc1C +CCOC(=O)C1=C(N)Oc2[nH]c(=O)[nH]c(=O)c2C1c1ccco1 +COc1c(C)cnc(CNC(=O)Nc2nccs2)c1C +CN(Cc1ncnn1C)C1CCN(c2sccc2C#N)C1=O +CC(C)c1cnc(NC(=O)c2ccc(N3CCNC3=O)cc2)s1 +CC(=O)N1CCN(Cc2ccc3c(c2)OCO3)C(=O)C1 +O=C(CCC(=O)OCC(F)(F)F)Nc1nc2ccccc2s1 +CCc1cc(Br)c(OC)c(C(=O)N(C)C)c1 +CCC(C(=O)Nc1cccnc1)n1nnc2ccccc2c1=O +Cc1ccc(NC(=O)C(O)c2ccccc2)c(OCC(=O)N(C)C)c1 +CCN(Cc1cccc(F)c1)C(=O)c1scnc1C1CC1 +COc1cc(C(=O)NCCc2ccccn2)cc(Cl)c1OC +CNC(=O)C(C)Sc1nc2ccccc2n1CCOC +N#Cc1cccc(OCc2noc(-c3ccccc3)n2)c1 +CCCCS(=O)(=O)NCC(=O)N1CCC(c2nc[nH]n2)CC1 +O=c1[nH]c(N2CCc3ccccc32)nc2ccccc12 +C=CCN(Cc1nc(-c2ccccc2)no1)C(=O)C(N)c1ccccc1 +FC(F)(F)Oc1ccc(-n2cc(-c3ccncc3)cn2)cc1 +Cc1ccc(-c2nc(N)c(C#N)c(-c3cccnc3)c2C)o1 +c1ccn2cc(CSc3nnc(C4CC4)n3C3CC3)nc2c1 +CC1CC1C(=O)Nc1cccc(CS(=O)(=O)NC(C)(C)C)c1 +CN1CC(C(=O)NCC#CCOc2ccccc2Cl)CC1=O +CCc1ccc(S(=O)(=O)Nc2cc(C(N)=O)ccc2Cl)cc1 +CCN(CC)C(=O)Cn1c(=O)c2nnc(C)n2c2ncccc21 +COc1cccc2c(C)nc(Nc3nccc(C)n3)nc12 +Cc1noc(C)c1CCC(=O)Nc1ccc(CN2CCOC2=O)cc1 +COC(=O)c1ccccc1Sc1snnc1C +CC(C)C(C)(CNC(=O)c1cscn1)NC(=O)c1cscn1 +CC=Cc1ccc(OC(=O)Cc2csc(CC)n2)c(OC)c1 +CNC(=O)c1ccc(=O)n(Cc2cccc(Br)c2)c1 +O=C(CC1(O)CCCCC1)NCCc1ccn(-c2cccc(F)c2)n1 +Cc1cc(Oc2nn(Cc3ccccc3)cc2C)n2ncnc2n1 +CCCn1c(CNS(=O)(=O)c2ccc(C)cc2)nc2cccnc21 +Cc1c(Br)cccc1COC(=O)COCC1CCCO1 +Cn1cc(CCNC(=O)N2CCN(Cc3cccnc3)CC2)cn1 +CCCn1c(SCC(=O)NCC)nc2cc(Cl)ccc21 +CN1CCN(C(=O)c2onc(-c3ccccc3)c2N)CC1 +CCCc1c(CO)nnn1-c1cccc2ccccc12 +CCCN(C(=O)c1ccccn1)c1cccc(N)c1 +COc1ccc(C)cc1CC(=O)Nc1ccc(N2CCCC2)nc1 +O=C(CS(=O)(=O)c1nnc(N2CCCC2)s1)N1CCCCC1 +COc1ccc(CC(=O)OCC(=O)Nc2ccc(F)c(F)c2)cc1 +Cc1ccccc1C(=O)NCc1ccc2c(c1)CCO2 +CSc1cccc(-n2nnc(CO)c2C(C)(C)C)c1 +CCn1cnnc1CNC(=O)C1CC(=O)N(CC2CC2)C1 +COc1cc(CO)ccc1OCc1ccccc1Cl +COC(=O)C1(CNC(=O)Cc2noc3ccccc23)CCCCC1 +CCOCCCNC(=O)c1nnsc1-c1ccc(C)cc1 +COc1ccc(CNC(=O)NC(C)c2cccs2)cc1 +Cc1nnc(SCC(=O)N2CCCc3ccccc32)n1N +CN(Cc1csc2ccccc12)C(=O)CCS(=O)(=O)N(C)C +CN(Cc1ccc(F)cc1)C(=O)c1cccc(C#N)c1 +COc1ccc(-n2nc(C)c(N)c2C)cc1Cl +CCCn1cc(NC(=O)c2cc(C(N)=O)cs2)cn1 +COc1ccc(CC(=O)Nc2c(C)cccc2C)c(OC)c1 +CSc1ccc(OCc2csc(C)n2)cc1 +CCCC1CN(C(=O)CNC(=O)OCc2ccccc2)CCO1 +CC(NC(=O)Cn1c(C2CC2)nc2ccccc21)c1ccccn1 +Cc1ccc(Br)cc1NCc1noc(-c2ccoc2)n1 +CCOC(=O)c1[nH]c(C)c(C(=O)OCc2nc(C)no2)c1C +Cc1ccc(CNc2ccc(N)c3cccnc23)s1 +COc1ccc(NC(C)C(=O)N(C(C)C)C(C)C)cn1 +C=C(C)CN(CC)C(=O)NCc1cccc(COC)c1 +CC(C)n1ncc2cc(NC(=O)C3Cc4ccccc4CN3)cnc21 +C=CCn1c2c(ccc1=O)CCN(C(=O)c1ccc[nH]1)CC2 +COc1ccc(C2CCCN2C(=O)C2CCN(C(C)=O)CC2)cc1 +COC(=O)c1ccccc1OC(=O)Nc1ccc(F)cc1 +Cc1ccc2c(c1)N(Cc1nnc(C(C)C)o1)CC2 +Cc1cccc(-n2nc(C(C)(C)O)c(=O)cc2C)c1C +CC1CN(S(=O)(=O)NC(C)(C)CC(C)(C)C)CC(C)O1 +Cc1ccc(C(=O)NCCCc2ccc(Cl)cc2)c(=O)n1C +Cc1cccc(C(=O)N2CCC3(CCN3c3ncccn3)C2)c1 +O=C(NCCOc1ccccc1)c1csc(Nc2cccnc2)n1 +CC(C)Cc1cc(C(=O)NCCN2CCCC2=O)n(C)n1 +COc1cccc(C2CCCN2C(=O)NC(C)C2CCCO2)c1 +Cc1nc(CCNC(=O)NCC2Cc3ccccc3O2)cs1 +CC(O)CC(C)CNC(=O)Nc1cccc(NC(=O)C2CC2)c1 +CCOC(=O)c1[nH]c(C)c(C(=O)NCCc2cccc(C)c2)c1C +COc1ccc(CCN2CC(NC(=O)C3CCC3)CC2=O)cc1 +CC(NCc1ccncc1)C(=O)c1ccc(N)cc1 +Brc1ccccc1-c1nnc2scnn12 +O=C1CN(c2nc3nonc3nc2N2CCCCCC2)CCN1 +CCCNC(=O)C1CCN(C(=O)C2CC(=O)N(C(C)(C)C)C2)CC1 +CCOC(=O)C1CCCN(c2nn3cnnc3c3ccccc23)C1 +Cc1c(NC(=O)c2ccoc2)cccc1S(N)(=O)=O +Cc1ccc(CNC(=O)CNC(=O)NCc2ccccc2)cc1F +Cc1nc(CS(=O)(=O)c2ccc(C(F)(F)F)cn2)no1 +CC(C)(CNC(=O)CCCN1CCOC1=O)c1ccncc1 +Cc1cc(NC(=O)CNC(=O)c2cccc(F)c2)c2ncccc2c1 +CCOc1ccc(CNC(=O)C2(c3ccc(F)cc3)CC2)cc1OC +COC(=O)CNS(=O)(=O)c1ccc2c(c1)C(C)(C)C(=O)N2C +Cc1sc2ncnc(N3CCN(Cc4cccs4)CC3)c2c1C +CCOC1CCN(C(=O)c2n[nH]c(=O)c3ccccc23)CC1 +O=C(c1ccoc1)N1CCCn2cnc(COCC3CC3)c2C1 +c1ccc(OCCSc2nnc(C3CC3)n2C2CC2)cc1 +CC(C)c1nc(CC(=O)NCc2cn(-c3ccccc3)nn2)cs1 +CC(C(=O)NC1CCCc2occc21)n1cccn1 +CC(=O)NC1CCN(c2cc(C)nc3cc(C)nn23)C1 +COc1ccc(OC)c(CC(=O)N(Cc2ccccc2F)C2CC2)c1 +Cc1noc(C)c1S(=O)(=O)Nc1ccc(C(F)(F)F)cc1 +O=C(NC1CCCCC1)c1nccn1-c1ccccn1 +Cc1cc(C)n(CCCNc2ncnc3c(C)n[nH]c23)n1 +Cc1ccc(NC(=O)c2ccc(-c3cscn3)cc2)nc1 +CC(C)c1ncc(C(=O)Nc2c[nH]cc(Br)c2=O)s1 +COc1ccc2[nH]cc(CC(=O)NCc3cc(C(C)C)no3)c2c1 +COc1ccc(-n2ccc(C(=O)NCC3CC3)n2)cc1 +COc1ccc(-c2n[nH]cc2C(=O)N2CCNC(=O)C2)cc1 +Cn1cnnc1CCNC(=O)c1cc2c(F)cccc2[nH]1 +Cc1cc(=O)n(CCNC(=O)NCc2cccc3ccccc23)cn1 +COCc1nc(C(=O)NC(C(N)=O)c2ccccc2)cs1 +COc1cc(OC)cc(-c2nnc(Cc3ccccc3OC)o2)c1 +Cc1ccc(C(=O)N2CC3COCC3(CNS(C)(=O)=O)C2)cc1 +O=C(Nc1ccc(-c2nccs2)cc1)NC1CC1 +CCOC(=O)CSc1nc(-c2ccccc2)cc(=O)[nH]1 +CCOc1cn(C)c(C(=O)NCc2ccccc2)cc1=O +O=C(NCCc1nc2ccc(F)cc2[nH]1)c1cc(C2CC2)on1 +O=C(NCCc1nc2cc(F)ccc2[nH]1)c1ccncc1 +CCCCNC(=O)C1CCN(C(=O)C(CC)CC)CC1 +Cc1cccc2[nH]c(C3CCN(C(=O)c4n[nH]c5c4CCC5)CC3)nc12 +CC(C)n1nccc1NC(=O)Cc1csc(Cc2ccccc2)n1 +CN(CC1CCCCC1)C(=O)COc1cccc(-c2nnco2)c1 +COc1ccccc1S(=O)(=O)N(C)Cc1ccccc1 +COc1ccc(OC)c(CCC(=O)N2CCc3ccccc3C2)c1 +Cc1cccc(CNC(=O)N(Cc2ccccc2)CC2CCC2)n1 +Cc1nc(C2(NC(=O)NCc3nnc4ccccn34)CCCC2)no1 +CCOC(=O)c1sc2[nH]c(CNCC(C)C)nc(=O)c2c1C +N#CCCN(CCC#N)C(=O)c1ccc(C(N)=O)nc1 +CCc1ccc(Cc2nnc(NC(=O)C3CCCC3)o2)cc1 +CC1Oc2ccccc2OC1C(=O)NCC#Cc1ccccc1Cl +O=C(Nc1cnc(-c2ccccc2)nc1)c1ccccn1 +Cc1ccc(N)c(S(=O)(=O)NCCS(N)(=O)=O)c1C +CCCN(CCO)S(=O)(=O)c1ccc(F)c(C)c1 +Cc1cccc(OS(=O)(=O)c2cccc(S(N)(=O)=O)c2)c1C +COc1ccc(C)cc1S(=O)(=O)Nc1ccc(N)cc1C +COc1ccccc1COC(=O)c1cccc(C)n1 +CCOC(=O)CC1C(=O)NCCN1C(=O)NC1CCCCC1 +CC(C)NC(=O)c1cc(-c2ccco2)n(-c2ncccc2Cl)n1 +CCOC(=O)CCN1CCC(N2CCOC(C)C2)CC1 +COc1cccc(CN(C)C(=O)c2cccnc2SC)c1 +CCS(=O)(=O)c1noc(C(=O)N(C)c2ccccc2)c1N +CCN1C(=O)CSc2ccc(C(=O)NCCCOC)cc21 +CC(C)N(CC(F)(F)F)C(=O)c1ncoc1-c1cccs1 +Cc1noc(C)c1CNC(=O)C1CCN(c2ccc(Cl)cn2)CC1 +CCc1noc(CC)c1CNC(=O)NC1CC1c1ccccc1F +CCc1onc(C)c1NC(=O)NCC(=O)Nc1cccnc1 +CCC(=O)NCC(=O)NCCc1ccccc1Cl +COc1ccc(CNC(=O)NCc2ccc(C(=O)N(C)C)cc2)cn1 +CCOC(=O)C1CCN(C(=O)CN2CCCc3cc(F)ccc32)CC1 +COC(=O)NCC(=O)N1CCCC(NC(N)=O)C1 +CC(C)c1nnc(NCc2sccc2Br)o1 +Nc1cc(F)c2oc(-c3ccc(Cl)cc3)nc2c1 +Cn1cn[nH]c1=NC(=O)c1ccc(Cl)cc1Cl +Cc1cccc2c(=O)[nH]c(CSc3ccccc3O)nc12 +O=C(NCCC(=O)N1CCc2ccccc21)c1ccccc1Cl +COC(=O)CCN(Cc1ccccc1)C(=O)c1cnc2ccccc2n1 +COCCOCCNC(=O)N1CCOC(c2ccc(F)c(F)c2)C1 +O=C(C1CCCC1)N1CCN(c2ccccc2O)CC1 +C=CCN(CCc1ccccc1)C(=O)c1cccc(-n2cnnn2)c1 +COc1cccc(OCC(=O)N(C)Cc2cccc(C#N)c2)c1 +COc1cccc(C(=O)C2CCCN2S(=O)(=O)N(C)C)c1 +COc1cccc(N2CCN(C(=O)Nc3cccc(C#N)c3)CC2)c1 +Cc1ccncc1NC(=O)N(C)CCCc1ccccc1 +COC(=O)c1c(O)cn(-c2cc(C)cc(C)c2)c1C +CC1=CC(C)=NC(=O)C1CNC(=O)c1ccc(OC(C)C)cc1 +CCCc1cc(C(=O)N2CC3CCC(C2)N(CCOC)C3=O)n(C)n1 +N#CC1(NC(=O)CCc2c[nH]c3ccccc23)CCCC1 +O=C(Cc1ccc2c(c1)OCCO2)NCc1cn2ccccc2n1 +O=C(c1ccc(-c2ccncc2)nc1)N1CCOCC1 +CCCC(C(=O)NCc1nc(C)sc1C)c1ccccc1 +CS(=O)(=O)NC1CCN(Cc2cccs2)C1 +Cc1cc2oc3c(c(=O)c2cc1Cl)C(c1cccc(O)c1)NC3=O +Cc1ccc(CC(=O)N2CCN(C(=O)NC(C)C)CC2)cc1 +CNC(=O)c1ccc(NC(=O)Nc2ccccc2)cc1 +O=C(CCCOc1ccc(Cl)cc1)N1CCCCC1 +CCc1ccc(CN(C2CC2)S(=O)(=O)CC)cc1 +Cn1nc2c(cc1=O)CN(Cc1cc(Cl)cc3cccnc13)CC2 +NC(=O)C1CCC(NC(=O)CC2CCCCC2)CC1 +COc1ccc(OC)c2c1cc(C(=O)Nc1ccncc1)n2C +CN(Cc1ccc2c(c1)OCCO2)S(=O)(=O)c1ccccc1 +CC(C)CCOC1CCCCC1NC(=O)c1cnns1 +CCCc1cc(=O)n2nc(NCc3ccccc3Cl)[nH]c2n1 +CC(C)C(=O)Nc1cccc(NC(=O)COc2ccc(F)cc2)c1 +Cn1nnc2cc(C(=O)Nc3nc4ccc(F)cn4n3)ccc21 +O=C(Nc1ccc(-c2csnn2)cc1)Nc1cn[nH]c1 +Cc1sc(=O)n(CC(=O)Oc2ccc3ccc(=O)oc3c2)c1C +CC(=O)Nc1ccc(C(=O)Nc2cc(C)ccc2C)s1 +CS(=O)(=O)c1ccc(NC(=O)c2cccc(F)c2F)cn1 +CCN(CC(=O)NC)S(=O)(=O)c1ccc(C)cc1 +CCOC(=O)CCn1c(C(C)(C)C)cn(CC)c1=O +OC1(CNc2nnc(C3CC3)s2)CCCCC1 +CNC(=O)c1cc(-c2cccc(OCC(C)C)c2)nc(N)n1 +CC(=O)Nc1ccc(C(=O)COC(=O)c2cc(C)cc(C)c2)c(F)c1 +CCn1cc(C#N)c(=O)n(Cc2ccccc2F)c1=O +C#CCNC(=O)N(C)C(C)Cc1ccccc1OC +c1cnc2c(-n3nc(C4CC4)nc3-c3csnn3)cccc2c1 +OCC1CCN(c2cncc(Br)c2)CC1 +Cc1cc(=O)n(CCNC(=O)c2cc3ccccc3o2)cn1 +CCn1c(=O)c(C(=O)NCc2ccccc2F)nc2cccnc21 +Nc1cccc2c1CN(CCc1ccccn1)C2=O +CN1C(=O)c2cc(Cl)ccc2NC1c1c[nH]nc1-c1cccs1 +CCc1nc(CNC(=O)CCc2cn3ccccc3n2)no1 +COCC(C)NC(=O)Nc1ccc(-c2nc(C)cs2)cc1 +CC(O)(CNC(=O)NCC#Cc1ccccc1)c1ccc(F)cc1F +CC(=O)Nc1ccc(Cl)c(NC(=O)N2CC(C)CCC2C)c1 +N#Cc1cnc2ccccc2c1N1CCCC(C(N)=O)C1 +CCN1C(=O)C(C)(C(=O)NCCO)Oc2ccccc21 +CCOC(=O)c1ccc(NC(=O)c2ccc3c(c2)nnn3C)cc1 +CC(C)(C)NC(=O)CNC(=O)C1CCN(C(=O)c2ccoc2)CC1 +CNC(=O)c1cccc(NC(=O)N(C2CC2)C(C)c2ccco2)c1C +COc1ccc(S(=O)(=O)CC(=O)N2CC(C)OC(C)C2)cc1 +CCOC(=O)C(N)c1c(Br)ccc(F)c1F +CCc1ccc(CC2Oc3cc(N)ccc3N(C)C2=O)cc1 +Cc1ccc(CNC(=O)c2c[nH]nc2NC(=O)c2cscn2)cc1 +Cc1noc(C)c1S(=O)(=O)Nc1cnn(C2CCOCC2)c1 +NC(=O)N1CCCC(C(=O)Nc2cccc3ccccc23)C1 +CCn1cc(CC(O)Cc2cccc(Cl)c2)cn1 +CN(Cc1ccc(Br)cc1)CC(C#N)CCC#N +Cc1cccc(NC(=O)Cn2cnc(C(C)C)cc2=O)n1 +Cn1cnc2cc(-c3cc(C#N)nn3-c3ccccc3)ccc21 +CC(=O)c1ccc(NC(=O)NCC(CO)Cc2ccccn2)cc1C +CCS(=O)c1ccccc1C(=O)NCc1ccccc1F +N#CCCN(C(=O)Cn1nnc2ccccc2c1=O)c1ccccc1 +Cc1nnc(C(C)N2CCN(C(=O)c3cccc(F)c3)CC2)o1 +Cc1cc(C2CCCN2C(=O)C2CCCN(c3ncccn3)C2)no1 +CN(Cc1cccnc1)C(=O)c1cccc(Oc2ccccc2)c1 +CC(Oc1ccc(C#N)cc1)C(=O)N1CCCCC1Cn1cccn1 +COc1ccccc1NC(=O)c1cccc(S(=O)(=O)N(C)C)c1 +COCc1n[nH]c(-c2cc(OC)c(OC)c(OC)c2)n1 +O=C(OCc1nc2ccccc2s1)c1ccc(-n2cccn2)nc1 +CC(NC(=O)c1c(Cl)cccc1Cl)C1CCOC1 +COc1ccccc1CN1CC(C(=O)NCCC(C)C)CC1=O +O=C(NCCNC(=O)C1CCCO1)c1ccc(Cl)cc1 +Cc1[nH]c2ccccc2c1C(=O)NCCC(=O)NC1CCCC1 +N#CCc1nc2cc(N)ccc2n1Cc1ccccc1F +COCc1nnc(NC(=O)C2CC(=O)N(Cc3ccccc3)C2)s1 +CCCC(C)NC(=O)CS(=O)c1ccc(N)cc1 +Cc1cn2c3c(=O)[nH]c(=O)n(C)c3nc2n1-c1cccc(Cl)c1 +CCN(C(=O)CSc1nc(C)cs1)C1CCCCC1 +CC(NCC(=O)Nc1cnccn1)c1ccccc1-n1cccn1 +Nc1ccc(S(=O)(=O)CCCOc2ccc(F)cc2)cc1 +Cc1cc(NC(=O)CNc2ccc(C(C)(C)C)cc2)n(C)n1 +N#Cc1cccc(NC(=O)CNc2ccccc2Br)c1 +COc1ccc(C2CCCn3nc(N)nc32)cc1F +Cc1noc(COCC(=O)Nc2ccc(-c3cc[nH]n3)cc2)n1 +COc1ccc2c(c1C)OCC(c1cc3c(cc1C)OCCO3)C2=O +CCCCS(=O)(=O)c1nc2ncc(C)cc2s1 +Cc1oc(-c2ccsc2)nc1CN1CCOC(Cn2cncn2)C1 +Cc1noc(C2COCCN2Cc2ncc(C(C)C)s2)n1 +O=C(Cc1coc(-c2cccs2)n1)N1CCOCC1C1CC1 +O=C(NCCC(=O)N1CCCCCC1)c1ccccc1O +COC(=O)CCNC(=O)C(N)c1ccc(N)cc1 +COc1ccc(OC)c(-c2noc(NC3CCCC3)n2)c1 +CCc1nc2c(N(C)Cc3cccc4ncccc34)ncnc2o1 +O=C1COc2c(cccc2C(=O)N2CCCCC2Cn2cccn2)N1 +NC(=O)CSc1nnc(CCc2ccccc2)n1N +CC1CCC2(CC1)CN(CCC#N)c1ccc(F)cc1N2 +COC(=O)c1cccc(NCC(=O)NC2(C#N)CCCCC2)c1C +CC1OCCC1NC(=O)c1cn(C)nc1C(C)(C)C +Cc1cc(CN2CCN(C(=O)Cc3ccc4c(c3)OCO4)CC2)on1 +Cc1cccc(CN2CCCn3c(CNC(=O)C(C)C)nnc3C2)n1 +c1cc(CN2CCOC3CN(c4nccs4)CC32)ccn1 +COc1cc(CCC(=O)N2CCCC(C)C2)cc(OC)c1OC +COc1ccc2cc(CNc3ccc(NC(C)=O)cc3)c(=O)[nH]c2c1 +COc1ccc(Cn2cc(C(=O)N(C)Cc3nonc3C)nn2)cc1 +CCCn1nc(C(=O)N2CCCc3ccccc32)ccc1=O +CN(CCCC(=O)Nc1ccc(F)c(Cl)c1)C(=O)OC(C)(C)C +COC(=O)c1ccsc1NC(=O)c1ccc(OCC2CC2)cc1 +Cc1ccc(CNC(=O)c2cc(C)nc3c2cnn3C(C)C)cc1 +CCN(Cc1cccc(NC(=O)C2CC(=O)N(C(C)C)C2)c1)C(C)=O +Cc1cc(NC(=O)N2CCN(CC(=O)N3CCCC3)CC2)ccc1F +c1cnc2c(c1)CCC2Nc1nccc(C2CCCC2)n1 +O=C(CCS(=O)(=O)N1CCOCC1)NCc1ccc(F)cc1 +Cc1nccc(CNC(=O)N2Cc3ccccc3N(C)CC2C)n1 +CC(C)Cc1cc(C(=O)NCc2ccccc2-n2cncn2)n(C)n1 +Nc1ccc2c(c1)C(=O)N(c1cccc(Cl)c1)C2 +Cc1csc(NC(=O)C2CCN(C(=O)c3ccc(F)cc3)CC2)n1 +CC1CCCN(S(=O)(=O)NCCC(=O)NCc2ccccc2)C1 +CN(Cc1nnc2n1CCC2)C(=O)c1cc(Br)c[nH]1 +CCCc1nc2sc(C(=O)OCCOC)c(C)c2c(=O)[nH]1 +COCCn1c(SCCn2c(=O)oc3cccnc32)nc(C)c1C +CC(C)Cc1noc(CN2CCCc3ccccc32)n1 +Fc1cccc(CN2CCc3nc(N4CCCC4)ncc3C2)c1F +C=CCNC(=O)CCc1nnc2n(CCC)c(=O)c3sccc3n12 +CCn1nc(C)c(CN2CCC(N3CCOC(C)C3)CC2)c1C +CCCNC(=O)C(C)NC(=O)Nc1ccc(C)cc1Br +CCOc1ccccc1NC(=O)c1oc2ccccc2c1NC(C)=O +Cc1cccc(-c2[nH]ncc2CN2CCOC(c3cccs3)C2)c1 +CNC(=O)c1cccc(OCc2cn3ccccc3c2C#N)c1 +O=C(Nc1nncs1)N1CCN(Cc2ccsc2)CC1 +COc1cccc(C(=O)Oc2cccc(N3CCCC3=O)c2)c1F +CCN(CC1CCOC1)C(=O)CCc1nc(-c2cccnc2)no1 +Cc1cc(F)c(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)cc1F +CCOC(=O)C1CCCN(C(=O)c2cc(C)c(CC)s2)C1 +COCCC(C)NC(=O)Nc1cc(OC)ccc1F +CCNS(=O)(=O)c1cc(C)ccc1-n1cnnn1 +Cc1[nH]ncc1CCCNC(=O)c1ccc(Br)cc1 +CCn1cc(C(=O)NCc2ccco2)c(=O)c2cc(F)ccc21 +COC(=O)c1nn(C)c(C)c1NC(=O)c1cccc(C)c1 +Cc1cccc(C)c1NC(=O)c1cccc(NS(C)(=O)=O)c1 +CC(=O)c1sc(NC(=O)Nc2ccc(F)cc2F)nc1C +O=C(Cc1ccc(O)cc1)N1CCC2(CCC(=O)N(CCO)C2)CC1 +CN(C)C(=O)Cc1ccc(NC(=O)Cc2ccccc2Cl)cc1 +Cc1ccccc1Nc1nc(N)nc(CN2CCOC(C)(C)C2)n1 +CCOC(=O)CCNC(=O)N1CCCC(N2CCOCC2)C1 +Cc1nn(C)c2nc(C(C)C)cc(C(=O)N3CCOCC3C)c12 +COc1ccc(OC)c(NC(=O)C2CC2(Cl)Cl)c1 +CC(NC(N)=O)C(=O)N1CCOC(c2ccc(Cl)cc2)C1 +CC(=O)Nc1ccc(-c2nc3ccc(F)cn3c2N)cc1 +Cc1c(Cl)c(C(O)Cc2ccccc2)cc2c1NC(=O)C2 +CCC(CC)N1CCN(C(=O)Cc2ccccc2)CC1 +O=C(Cn1nc(-c2ccco2)ccc1=O)NCc1ccc(Cl)cc1 +O=C(Nc1cnccc1SCCCO)c1cccc(F)c1F +Oc1ccc2c(c1Cl)C(C=Cc1ccncc1)NCC2 +CC(C)(C)NC(=O)COC(=O)c1ccc(Cl)c(N)c1 +CC(=O)NCC(=O)NCc1nn(CC(C)C)c2ccccc12 +COc1ccc(CNC(=O)c2ccc3c(c2)OCCCO3)cn1 +COC(=O)C(C)Sc1ccc(C(=O)N2CCCC2)cn1 +Cc1ccc(C)c(Cn2nnn(-c3ccccc3)c2=O)c1 +O=C(CCNC(=O)Nc1cc(F)ccc1Cl)NC1CCCCC1 +O=C1OCC2Cc3sccc3C(c3ccccc3)=C12 +N#Cc1ccc(NC(=O)CC(C#N)c2ccccc2F)cc1 +CC1=NC(=O)C(CC(=O)NCc2ccc(-n3cccn3)nc2)C(C)=N1 +COc1cccc(NC(=O)c2c(C)nc3ccccn23)c1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)Nc2cccnc2)cc1 +COc1ccc(-c2nn3c(C)nnc3s2)cc1Br +Cc1ccc(OCCNC(=O)C(C)n2nc(C)ccc2=O)cc1 +COc1ccc(-c2onc(N)c2-c2cc(OC)c3c(c2)OCO3)cc1 +CCCOc1ccc(CNC(=O)c2ccccc2)cc1OC +CC(C)C(OC(=O)c1cn(CC(N)=O)nn1)c1ccc(F)c(F)c1 +O=C(CSc1nnc(-c2ccccn2)o1)Nc1ccc(Cl)cc1 +COc1cc(C)c(C(=O)NCCc2sc(C)nc2C)cc1OC +CC(C)C(CNC(=O)C(C)(C)C)N1CCOCC1 +CC(C)CC1(C(=O)NCC(O)c2cccs2)CCC1 +COc1cccc(C(=O)Nc2cccc(-c3noc(C)n3)c2)c1OC +O=S(=O)(NCCc1ccc(O)cc1)c1cn[nH]c1 +Cc1ccccc1SC1CCN(C(=O)c2ccc(O)cc2)CC1 +C=CCNC(=O)CSc1nnc2n1CCCCC2 +CC(CCc1ccc(O)cc1)NC(=O)c1ccc(-n2cnnc2)cc1 +COc1ccc(NC(=O)CN(CCc2ccccc2)C(C)=O)cc1C +CC(C)CNC(=O)C(C)NC(C)c1ccc2c(c1)OCCO2 +C=CCc1ccccc1OC(=O)Cn1c(=O)cnc2ccccc21 +COc1cccc(OC)c1C(=O)N1CCN(CCC#N)CC1 +COc1cc(=O)c(C(=O)NCC2CC2)nn1-c1ccc(F)cc1 +Cc1ccc(N(C)C(=O)Cc2ccc(C)nc2)c(C)c1 +CNc1nn(-c2ccccc2)c2c1C(=O)CC(C)(C)C2 +Cc1ccccc1CNS(=O)(=O)c1ccc2c(c1)OCCCO2 +O=C(NCc1ccccc1CO)C1CC2CCC1C2 +O=C(OCCc1cccnc1)c1scnc1C1CC1 +O=C(NCC(=O)N1CCCC1C1CCCC1)NCc1ccco1 +O=C1COc2ccc(C(=O)Nc3nncs3)cc2N1 +CC(=O)NCCn1nc(C(F)(F)F)c2c1CCOC2 +Cc1nc2cc(NCc3ccccc3OCC(=O)N(C)C)ccc2o1 +COc1ccc(CN2C(=O)Cc3ccccc32)c(OC)c1 +N#Cc1cccc(CN2C(=O)C(=O)c3cc(F)ccc32)c1 +O=C(NCc1ccc2c(c1)OCO2)c1cc(C2CC2)[nH]n1 +COc1cc(NC(=O)c2nc(C)oc2C)cc(OC)c1 +O=C(Nc1ccccc1)N1CCC2(CC(=O)N(c3ccsc3)C2)C1 +COc1ccc(S(=O)(=O)N(C)CC(=O)NC(C)(C)C)cc1C +O=C(CCNC(=O)NC1CCCCC1)Nc1cccc(Cl)c1 +CCOC(=O)c1cnn(C2CCCN(C(=O)c3cn(C)nc3C)C2)c1 +CCC(=O)c1ccc(OCC(=O)N2CCN(CCO)CC2)cc1 +CCc1cccc(CC)c1NC(=O)CSc1nc(C)cc(=O)[nH]1 +Cn1ccnc1CNC(=O)c1coc(COc2ccc(F)cc2)n1 +COC(=O)C(C)N(C(=O)c1nc(C)n2c1CCCC2)C1CC1 +CC(C)CCC(=O)N(C)Cc1nc2ccccc2[nH]1 +Cn1nnnc1SCC(=O)c1cccc(Cl)c1 +COc1cccc(C(=O)OCc2cc(=O)n3cc(C)ccc3n2)c1F +COC(=O)CCNC(=O)CN1CCN(c2cccc(Cl)c2)CC1 +CCc1nc(C)c(C(C)N(C)C(=O)Cc2c(F)cccc2F)s1 +Cc1c(Cl)cccc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +COC(=O)CCNC(=O)c1c(F)cccc1Cl +CC1CN(Cc2cccc3c2OCCCO3)C(C)CO1 +CNS(=O)(=O)c1cc(C(=O)N2CCOCC2)cc(C)c1C +Cc1ccsc1C(=O)Nc1[nH]nc(C(F)(F)F)c1C +CC1CN(C(=O)c2cn(Cc3cccc(Cl)c3)nn2)CCN1C +COc1cccc(CC(NC(C)=O)C(=O)N(C)c2nccs2)c1 +O=C(CCCOc1ccc(Br)cc1)Nc1nccs1 +COC(=O)C(CC(C)C)NC(=O)C1CCC(=O)N1 +COc1ncc(NC(=O)C2CCCC2)c(N2CCCC2)n1 +CCOC(C)c1noc(CSc2nnc(-c3ccoc3C)n2C)n1 +CC(=O)NC1CC(C)(C)Oc2ccc(C(O)C(C)(C)C)cc21 +Cn1cc(CNS(=O)(=O)c2cc(F)cc(F)c2)cn1 +CCCOc1ccc(C(=O)CCN2CCC(=O)CC2)cc1 +CCc1onc(C)c1NC(=O)COc1ccccc1Cl +O=C(CN1CCN(C(=O)NC2CCCCC2)CC1)NC1CC1 +COc1cc(C(C)=O)ccc1OCc1nc2ccccc2s1 +O=C(NCCCC(=O)N1CCc2ccccc21)NCC1CCOC1 +C#CCNC(=O)N(C)Cc1ccc(OC(F)F)cc1 +Cc1noc(CCC(=O)N(Cc2ccco2)c2ccc(F)cc2F)n1 +Cc1cc(C)n(Cc2cccc(CNC(=O)CN3CCOCC3)c2)n1 +Cc1c(C(=O)NCCOCCO)sc2ccccc12 +CCCNS(=O)(=O)c1cc(C(C)=O)ccc1Cl +COC(=O)C(NCc1nc(C)no1)c1ccccc1 +O=C(COc1ccc(F)c(F)c1)Nc1ccc2c(c1)OCCO2 +COc1ccc(CCNC(=O)c2c(C)cc(=O)oc2C)cc1OC +CCOC(=O)C1CCN(C(=O)c2nn(C)c3ccccc3c2=O)CC1 +Cc1nnc(SCC(=O)NCCOc2cccc(F)c2)s1 +Cc1cccc(NC(=O)NCCCOCC2CCCO2)c1 +Cn1c(SCc2ccccn2)nc2c(c1=O)SCC2 +O=C(C1CCN(c2cc(-n3cncn3)ncn2)CC1)N1CCCC1 +O=C(c1ccc(=O)n(Cc2ccccc2)n1)N1CCCC1 +NC1=NC(=O)C(Cc2ccccc2Cl)(c2cccc(Cl)c2)N1 +O=C(NCC1Cc2ccccc2O1)c1cccc(F)c1 +N#Cc1cccc(NC(=O)c2cc(C3CC3)nn2-c2ccccc2)c1 +COC(=O)CCN(CC1CCCO1)C(=O)C1COCCO1 +CCCc1nc(NCc2ccccc2OC)cc(OC)n1 +Cc1cc(-c2noc(CCC(=O)OCC3CCCO3)n2)ccc1F +O=C(NC1CC1)C1CCCN1C(=O)Nc1ccc(F)cc1 +O=C(CCc1ncc(-c2ccccc2)o1)Nc1ccc2c(c1)COC2 +O=C(Nc1ccccc1F)C1CN(C(=O)c2c[nH]c3ccccc23)C1 +Cc1c(C(=O)NCC(=O)NC2CC2)cnn1-c1ccccn1 +c1ccc(C2CCCCN2Cc2nc3ccccc3[nH]2)nc1 +Cc1ccc(-n2cnnc2SCC(=O)N(C)C(C)C)cc1C +CC(C)c1nnc2n1CCN(C(=O)C1Cc3cc(Cl)ccc3O1)C2 +CN(C)C(=O)CSc1nnc(-c2cccs2)o1 +Cn1c(=O)c(-c2nc(C3CCOC3)no2)cc2ccccc21 +CCOC(C)c1nc(CN(C)c2nc(N)nc3[nH]cnc23)cs1 +COc1ccc(C(C)=O)cc1CC(=O)N(C)c1ccc(F)c(F)c1 +CCOCc1ccc(CNC(=O)c2ccc3cc[nH]c3c2)cc1 +O=C(Nc1ccc(NC(=O)C2CCCC2)cc1)c1ccco1 +Fc1cccc(F)c1-c1csc(C2COCCN2)n1 +O=C(NCc1ccncc1)C1CCCN(c2ncnc3[nH]cnc23)C1 +O=C(NCCOc1cccnc1)C1COc2ccc(F)cc2C1 +O=C(NC1CNCc2ccccc21)c1ccccn1 +O=C(c1ccc2[nH]cnc2c1)N(Cc1ccccc1)Cc1ccccc1 +O=C(CC(F)(F)F)N1CCN(CC(F)(F)F)CC1 +CCOc1cc(C(=O)N(C)CC(O)C2CC2)ccc1C +COc1ccc(Br)cc1CC(C#N)CO +CC(C)c1noc(C2CCCCN2C(=O)c2cc(C3CC3)n[nH]2)n1 +CCC(NCc1cccnc1)C(O)c1ccc(C)cc1 +Cc1ccc(C(=O)CCCC(=O)NCC2CCCO2)cc1 +CN(Cc1ccsc1)C(=O)Cn1[nH]c(=O)c2ccccc2c1=O +O=S(=O)(Nc1cccc(N2CCCC2)c1)c1cccs1 +Cc1nnc(SCC(=O)N(C2CC2)C(C)C2CC2)s1 +Cc1ccc(-c2ccc(C(=O)N(C)CCNC(=O)C(C)C)s2)o1 +O=C(c1cncc(Br)c1)N1CCCCCC1 +C#CCOc1ccc(Br)cc1CN1CCOC(C#N)C1 +COCc1nc2n(n1)CCCC2Nc1nc(C(C)C)no1 +COCCN(CCC#N)C(=O)Cc1cccc(C)c1 +CC(C)N1CCc2nc(NC(=O)COc3ccccc3)sc2C1 +CC(=O)N1CC(C(=O)N2CCN(c3cc(C)ccc3C)CC2)C1 +CC(Cc1cccs1)N(C)Cc1ccc(C#N)o1 +CC(C)N(C)C(=O)CCCNC(=O)c1ccc(F)cc1F +COC(C)(C)c1noc(-c2ccc(NC(=O)C3CC3C)cc2)n1 +COc1ccc(C(=O)OCC2CN(CC(C)C)CCO2)cc1 +Cc1ccc(N2CCN(C(=O)Cc3cnccn3)CC2=O)cc1 +C#CCN(Cc1ccco1)C(=O)NCc1cccnc1 +Cc1ccc(-n2nnc(C(=O)Nc3ccccc3F)c2C)cc1 +Cc1cc(C(=O)OC(C(N)=O)c2ccc(F)cc2)c2ccccc2n1 +Cc1c(C)n(Cc2ccco2)c2ncn3nc(-c4ccccn4)nc3c12 +CCC(CC)CNc1cc(-n2cnnn2)ccc1F +CC(=O)N1CCC(C(=O)NC2C3CCOC3C2(C)C)CC1 +Cc1c(CCC(=O)N(CC(F)(F)F)C(C)C(C)C)cnn1C +CCC1CCC(NC(=O)NCCC(=O)N(C)C)CC1 +CC(C)(O)c1cn(C2CN(c3nc4ccccc4s3)C2)nn1 +CC(C)C(NC(=O)c1cccs1)C(=O)Nc1cccc(C#N)c1 +CC(C)(C)NC(=O)CNC(=O)CCc1cccc(Br)c1 +O=C(NC1CC1)C1CCCN1C(=O)CCc1ccccc1F +Cc1cc2nc(CC(=O)c3ccccc3)c(=O)[nH]c2cc1C +COC(=O)CCCCNC(=O)Nc1nc(C)c(C)o1 +CN(Cc1cccc(C#N)c1)C(=O)NC1CCN(CC(F)(F)F)C1 +Cc1cnc(NC(=O)c2ccc(CNC(=O)c3cccs3)cc2)o1 +COC(=O)COc1nc(CC(C)C)c2c(c1C#N)CCC2 +Nn1c(SCCn2cccn2)nnc1SCc1ccccc1 +COc1ccc(C(=O)c2ccc(NC(=O)C3CC3)cc2)cc1 +Cc1cc(C(=O)N2CCCCC2CCO)c2cnn(C)c2n1 +COc1ccc(CNC2CCCN(Cc3ccccc3)C2=O)cc1 +C#CCNC(=O)C(C)Sc1nccc(C(F)(F)F)n1 +Cc1nnc2n1CC(NC(=O)C1CC=CCC1)CC2 +Cc1ccc(C(=O)NCCc2ccc(-n3cccn3)cc2)c(=O)[nH]1 +O=C1Nc2cc(F)ccc2C1NCc1ccccn1 +Cc1cc(C)n2nc(C(=O)OC3CCCC3)nc2n1 +CC(C)(C)n1nc(C2CC2)cc1C(=O)N1CCC(C(N)=O)C1 +COc1ccc(OC)c(NS(=O)(=O)C2CC2)c1 +O=C(NCC1Cc2ccccc2O1)c1ccnc(-n2cncn2)c1 +COc1ccc(C(=O)CCC(=O)NC2CC2)cc1C(C)(C)C +CCC(=O)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1 +Cc1nn(C)c(C)c1CCN(C)S(=O)(=O)c1ccccc1Cl +CC1CCCC(CNC(=O)Cc2csc(N3CCCC3=O)n2)C1 +Cn1cc(-c2nc(-c3ccc(F)cc3)cs2)cn1 +CCN(CCO)C(=O)Cc1noc2c(C)cc(N)cc12 +CCC(C)c1ccc(NC(=O)C(NC(C)=O)C(C)C)cc1 +Cc1nn(C)c(C(=O)N2CCN(C)CC2)c1Br +O=S(=O)(CCn1cc(Cl)cn1)c1cccc(Br)c1 +N#Cc1c(-c2ccco2)cc(-c2cccs2)nc1N +CCCN(CCC)C(=O)c1cnc2c(c1)nc(N)n2CC +O=C(NCCn1ccc2cc(Br)ccc21)C1CCC1 +Cc1cc(NC(=O)NC(C)c2cccc(Br)c2)n(C)n1 +CCOC(=O)C(C)NC(=O)c1cccn1C(C)C +CN(Cc1ccsc1)C(=O)Cn1cc(-c2ccccc2)sc1=O +CCOCCC(=O)Nc1ccc(NC(C)=O)cc1 +CCc1nc(NC(=O)CCc2nnc(-c3ccsc3)o2)sc1C +CCOC(=O)c1cnn(CC(C)O)c1-c1ccccc1 +CN(Cc1cc2c(cc1OC(F)F)OCO2)Cc1cnnn1C +CNc1nc(-c2nnc3sc4c(n23)CCN(C)C4)cs1 +O=S(=O)(CCc1ccccc1)NCC(O)c1ccccc1 +O=C1CCc2cc(NC(=O)c3ccccc3F)ccc2N1 +COC(=O)c1cc(F)ccc1CN1CCn2c(nn(C)c2=O)C1 +CCOc1ccc(CC(=O)Nc2ccc3c(c2)CCC(=O)N3C)cc1 +Cc1cc(O)ccc1NC(=O)Cc1csc(=NS(C)(=O)=O)[nH]1 +Nc1c(C(=O)N2CCN(c3ccccc3)CC2)sc2ncccc12 +COc1cc(NC(=O)NCC#Cc2ccc(F)cc2)cc(OC)c1 +O=C(NCc1ccco1)Nc1ccc(Cl)cc1Cl +Cc1ccc(O)c(C(=O)Nc2cc(F)ccc2N)c1 +CN(C)c1ccc(C(=O)NCCn2ncccc2=O)cc1 +O=C(NCCc1ccncc1)c1cc2n(n1)CCCO2 +Nc1cccc2c(C(=O)NCCCN3CCOCC3)nccc12 +Cc1ccc(-c2noc(CCC(=O)N(C)C)n2)c(=O)n1C(C)C +CCCNC(=O)CCC(O)c1ccc(C(C)C)cc1 +Cc1cnn(CCC(=O)N2CCN(C(C)c3ccccc3F)CC2)c1 +Cc1n[nH]c(C)c1NC(C)c1ccc(F)c(F)c1 +COc1ccc(S(=O)(=O)CC(=O)NCc2ccc(F)cc2)cc1 +CCOc1cc(C(=O)Nc2ccc(OC(F)F)cc2)ccc1OC +Cc1ccccc1C(=O)NCCNc1ccc(Nc2ccncc2)nn1 +COCCOCC(=O)Nc1ccc(Cl)c(Cl)c1 +Cn1cc(CNCc2ccccc2-n2ccnc2)c(-c2ccncc2)n1 +N#Cc1ccccc1OCCN1CCc2cc(F)ccc2C1 +c1cnc(-c2nc(-c3ccc4c(c3)OCO4)cs2)cn1 +COc1cc(C)c(C(=O)Cn2cccn2)cc1C(C)C +Cc1ccc(C(=O)NCC2(N3CCOCC3)CCCCC2)c(=O)[nH]1 +Nc1cc(N2CCOCC2)nc(N2CCOCC2)n1 +O=C1COc2cc(-c3nc(C4CC4)nn3-c3ccccc3)ccc2N1 +CN(C)S(=O)(=O)c1ccccc1CNC(=O)C1CC=CCC1 +Nc1cccc(Nc2ncccc2C(F)(F)F)c1 +O=C(CCC1CCCCC1)NCc1ccc(N2CCCC2=O)cc1 +COc1ccc(NC(=O)NCCc2ccoc2)cc1 +CCc1onc(C)c1NC(=O)Cc1ccc(Br)cc1 +Cc1ccccc1CN(C)C(=O)NCCc1cccnc1 +Cn1cccc(NC(=O)c2ccc3c(c2)NC(=O)CO3)c1=O +CN1CCc2c(C#N)c(N3CCCC3)nc(NCC3CCCO3)c2C1 +COc1ccccc1CCN(C)C(=O)C(N)c1ccccc1 +CC(C)(C)C(=O)N1CC(c2nc(-c3cnccn3)no2)C1 +CNC(=O)NCC(=O)NC1CC1c1c(F)cccc1F +CN(C)c1ncccc1NC(=O)c1ccc(F)c(F)c1 +C=CCn1c(SCC(=O)NC2CCCC2)nc2ccccc2c1=O +Cc1cc(NC(=O)CN(C)c2ccc(Br)cc2F)no1 +COc1ccc(C(=O)OCc2nc(C)no2)cc1S(N)(=O)=O +CC1CCCN(S(=O)(=O)N(CCc2cccc(F)c2)C2CC2)C1 +COc1ccc(NC(=O)C2Cc3ccccc3C(=O)O2)cc1OC +CCOc1ccc(CN2C(=O)C(=O)c3cccc(C)c32)cc1OC +O=c1cc(-c2cncs2)nc(-c2ccccc2)[nH]1 +Cc1nnsc1C(=O)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +Cc1cnc(C(=O)N2CCc3ncnc(-c4cccnc4)c3CC2)cn1 +COc1ccc(CCCNc2ncc(C)cn2)cc1OC +Cc1cccc(OCCNC(=O)NCc2nnc(C(C)(C)C)s2)c1 +CC(C)(C)OC(=O)N1CC2(C1)C(=O)NCC2c1ccccc1 +CC1COC(c2ccccc2)C(C)N1Cc1ccn(C)c1 +CCC(CC)CN(CC)C(=O)c1ccccc1-n1cnnn1 +Nc1nc(-c2cccnc2)ncc1C(=O)NCC1CCCO1 +O=C1CC(c2ccccc2)N(C(=O)c2ccc3ccccc3n2)CCN1 +COC(=O)c1ccc(NC(=O)c2c[nH]nc2-c2ccccc2F)cc1 +COc1cccc(C(=O)N2CCN(C(=O)c3cccnc3)CC2)c1 +Cc1cc(-c2ccc(C(=O)N3CCCC3)c(N)n2)ccc1F +CC(=O)NCC(=O)NCC(=O)Nc1cc(-n2cccc2)ccc1F +COc1ccc(NC(=O)Cn2cnc3ccc(Cl)cc3c2=O)cc1 +CC(C)c1csc(NC(=O)C2CCN(c3ncccn3)CC2)n1 +O=C(Nc1ccccc1)C1CCCN1c1nc2ccccc2o1 +Cc1cc(C(=O)N2CCNC(=O)C2)c2c(C)noc2n1 +COc1cc(CO)cc2c1OCC(=O)N2Cc1ccc(F)cc1 +COc1ccc(-c2ccc3nc(N)nn3c2C)c(OC)c1OC +NC(=O)c1coc(-c2csc(NCCc3cccs3)n2)c1 +Cc1cccc(C(=O)NCC(=O)N(C)CCNC(=O)C(C)C)c1 +N#CC(c1cccc(Cl)c1Cl)N1CCC(O)CC1 +CC1CC1c1ccc(CNc2cncc(-c3nncn3C)c2)o1 +CCN(Cc1cc2ccccc2[nH]c1=O)c1ccc(O)cc1 +O=C(NCCCOc1ccc(Cl)cc1Cl)C1CCOC1 +COc1cccc(NC(=O)CCC(=O)c2ccc(C)c(N)c2)c1 +Cc1ccnc2nc(NC(=O)c3cccc(Cl)c3)nn12 +CSc1ccccc1NC(=O)c1ccccc1F +CCOc1ccc(C(=O)Nc2cc(C)on2)cc1OC +CCc1cccc(NC(=O)CSc2ncnc3[nH]cnc23)c1 +CCOCC(=O)Nc1ccc(C)c(S(=O)(=O)NC2CC2)c1 +CCOCCC(=O)N1CCC(C(=O)N2CCCCCC2)CC1 +Cc1ccc(-c2cc(C(=O)NCCc3cn4ccccc4n3)on2)cc1 +Cc1cc(C)cc(NC(=O)c2cccc3c2NCCC3)c1 +Cn1nc(C(=O)Nc2ccccc2-c2cccs2)ccc1=O +COc1ccc2nc(SCC(=O)NCCC(C)(C)C)[nH]c2c1 +Cc1n[nH]c(C)c1NC(=O)Nc1ccccc1N(C)Cc1ccccc1 +Cc1cc(C2CCC2)nc(NC(C)Cc2cnccn2)n1 +COc1ccc(Cl)cc1Cn1cnc2sccc2c1=O +O=C(CCc1cccc(Cl)c1)NCC(=O)Nc1cn[nH]c1 +COc1ccc(OCc2n[nH]c(-c3ccc(O)c(OC)c3)n2)cc1 +CCN(CC)C(=O)CN1C(=O)CNc2cc(OC)ccc21 +Cc1ccc(OCCCNc2ccc(C(N)=O)cc2)cc1 +COc1cccc(-c2ccc3c(n2)sc2c(=O)[nH]c(=O)[nH]c23)c1 +CC(C)N1CC(C)(C)Oc2ccc(C(=O)CN)cc21 +Cc1ccccc1-c1noc(-c2cccnc2N2CCOCC2)n1 +COc1ccc(CC(=O)NCc2c(C)cc(C)[nH]c2=O)c(OC)c1 +CC(CC#N)N(C)C(=O)Nc1ccccc1SCCC(N)=O +CCc1ncc2c(n1)CN(C(=O)C1C3C4CCC(C4)C13)C2 +N#Cc1ccc(-c2noc(-c3cccc4cn[nH]c34)n2)nc1 +Cc1cc2nc(NC(C)C3CC3)c3ccccc3n2n1 +COc1ccc(NC(=O)CNc2cccc(C)c2)cc1 +COCCOc1ccccc1NC(=O)c1cc(C(C)C)[nH]n1 +CCN(CCNC(=O)NCc1ccnn1C)c1ccccc1C +Cc1ccc(C)c(NC(=O)CSc2nncn2C)c1 +CCN(CC(C)C#N)S(=O)(=O)c1cccc(C(=O)N(C)C)c1 +O=C(CNc1cc(Br)ccc1F)N1CCOCC1 +CCNC(=O)C1(NC(=O)c2ccc(F)c(NC(C)=O)c2)CCCCC1 +NC(=O)c1n[nH]c2ccc(NC(=O)CCCNC(=O)C3CC3)cc12 +CC(C(=O)NC(c1ccc(F)cc1)c1nccn1C)N1CCOCC1 +CC(Sc1ccccc1F)C(=O)NCC(F)(F)F +COCCCn1cnnc1SCc1nc2c(C)cccc2c(=O)[nH]1 +COc1cc(C(=O)N(C)c2ccc(C)cc2)cc(N)c1OC +NS(=O)(=O)CCNC(=O)c1cccc(Cl)c1Cl +O=C(Nc1ccnn1C1CCCC1)c1ccc2ncsc2c1 +CC(=O)Nc1cc(Cl)ccc1NC(=O)c1ccnc(F)c1 +CN(CCC#N)C(=O)c1nc(-c2ccccc2)oc1C1CC1 +Cc1cc(NC(=O)c2cnn(-c3ccccc3Cl)c2C)no1 +NC(=O)COc1ccc(C2NC(=O)c3ccccc3N2)cc1 +Cc1nc(-c2cccc(NCc3cnc(C)s3)c2)n[nH]1 +CCCc1ccc(C(=O)Nc2ccc(=O)n(C)c2)cc1 +COc1ccc(CC(=O)Nc2cc(C#N)ccc2Cl)cc1 +CCOc1cc(Br)c(C(C)NC(C)=O)cc1OCC +NC(=O)COC(=O)C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +CN(Cc1ccccn1)c1ncnc2c1cnn2C +COc1ncccc1C(=O)N1CCN(C(C#N)C2CCCCC2)CC1 +CCCCSc1nc(N)cc(N2CCN(C(=O)N(C)C)CC2)n1 +COCCCN(C)C(=O)Cc1c(C)nc(-c2ccccn2)[nH]c1=O +O=C(CCc1ccc(Br)cc1)N1Cc2cncnc2C1 +O=C(Nc1ccc(-c2cnco2)cc1)c1ccc(NC(=O)C2CC2)cc1 +Cc1cnc(NC(=O)c2cc(Cl)ccc2F)s1 +Cc1ccnc(NCCCN2C(=O)COc3ccccc32)n1 +CCNC(=O)CSc1ncc(-c2ccccc2)o1 +COc1cc(Cl)c(-c2n[nH]c(C)c2N)cc1Cl +Cc1ccc(N2CCN(C(=O)Nc3ccccc3)CC2)nn1 +Cc1ccc(COC(=O)NCc2cccnc2)cc1 +CCOc1ccc(N)cc1COC1CCC(C)CC1 +CC1(C)CN(C(=O)c2cc3cc(F)ccc3[nH]2)CCO1 +CC1COCCN1CC(=O)Nc1ccnn1Cc1cccc(Cl)c1 +Cc1sc(=O)n(Cc2nsc(N(C)C)n2)c1C +CC(C)COc1cccc(CNC(=O)Cn2ccccc2=O)c1 +Cc1cc(CNC(=O)c2ccc(Cl)cc2N2CCCC2=O)c(C)o1 +COC(=O)c1cn(CC(=O)NC2CCCCCC2)c2ccccc12 +Cc1ccccc1C(C)NS(=O)(=O)c1ccc2c(c1)OCCCO2 +CCN(C(=O)CS(=O)(=O)c1cccc(C)c1)C1CC1 +O=C(COC(=O)C1(c2cccc(F)c2)CCCC1)N1CCOCC1 +CCN(CC)C(=O)c1cc(=O)c2cc(N)c(C)c(C)c2o1 +COCC(NC(=O)c1cccc(OC)c1F)c1ccc(C)o1 +CCC(C)OC(=O)c1ccn(-c2cccc(N)c2)n1 +O=C(Cc1ccc(-n2cnnn2)cc1)Oc1cccc(F)c1 +COc1ccc(CC(=O)Oc2cccc(N3CCCC3=O)c2)cc1 +CCOc1ccc2c(c1)CC(C(=O)N1CCC(O)C1)CO2 +CCn1nc2c(c(C(N)c3ccc(Cl)cc3)c1=O)CCC2 +CCn1c(SC2CCOC2=O)nnc1-c1ccccc1C +O=C(NCCO)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 +O=C(c1cn(-c2cccc(Br)c2)nn1)N1CCOCC1 +CCCNC(=O)CNC(=O)c1cc(Cl)ccc1N +NC(=O)c1cccnc1N1CCN(Cc2ccccc2F)CC1 +CC(=O)c1nnn(-c2nonc2-c2noc(C)n2)c1C +CCOc1c(Cl)cccc1NC(=O)CN(C)S(C)(=O)=O +Cc1cccc(C(=O)NCc2nnnn2-c2ccccc2)c1 +O=C(Cc1nc(-c2ccc(Cl)cc2)cs1)NCc1ccco1 +O=C(NCCn1nnn(-c2ccccc2)c1=O)c1ccc(=O)[nH]n1 +Cc1nn(C)c(C)c1CCC(=O)NC(C)c1cc2ccccc2o1 +O=C(Cn1nc(-c2ccccc2)ccc1=O)NCc1ccccn1 +O=C(NCc1ccc(Br)cc1)C1OCCc2ccccc21 +CCCCCC(C)NS(=O)(=O)c1cnn(C)c1 +CC(=O)NC(CC(=O)Nc1nnc(C)s1)c1ccc(C)cc1 +O=C(CNC(=O)c1csnn1)Nc1nccs1 +COC(=O)C1Cc2ccccc2N1C(=O)c1cccc2c1OCO2 +CCC(C)NC(=O)CCc1cc(OC)c(OC)cc1Br +C#CCN1CCC(C(=O)NCCc2cccc(C(=O)OC)c2)CC1 +CN(CCN1CCOCC1)C(=O)Nc1ccc2[nH]ccc2c1 +COc1ccc(C(=O)CC(C#N)c2ccc(F)cc2)cc1OC +CC(C)Cc1noc(CNc2ccc(NC(=O)C3CC3)cc2)n1 +COCCOc1cccc(C2NC(=O)c3c(C)cccc3N2)c1 +O=C(Nc1cccc(N2CCOC2=O)c1)c1ccccn1 +CCN(CC(C)C#N)C(=O)CNc1ccccc1C(F)(F)F +CC(C)NC(=O)C1CCCC(NC(=O)c2scnc2C2CC2)C1 +NC(C(=O)NCc1cccs1)c1cccc(F)c1 +Cc1nc2ccccc2c(=O)n1CC(O)c1ccc(F)cc1 +CN(CC(=O)N1CCc2ccccc21)c1ncnc2[nH]cnc12 +NC(=O)COC(=O)C12CCC(=O)N1c1cc(Cl)ccc1S2 +CC(C(=O)N1CC(=O)Nc2ccccc21)N1CCc2sccc2C1 +Cc1ccc(C(=O)NCC(=O)N(C)CCC#N)cc1C +Cc1ccc(NCCC(N)=O)c(Br)c1 +CC(NS(=O)(=O)c1cn[nH]c1)c1ccccc1Br +Cc1occc1C(=O)N1CC2CCCN(C(=O)c3ccoc3C)C2C1 +O=S(=O)(c1cc(F)ccc1F)N1CCN(c2ncccn2)CC1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)OCC(=O)NC(C)C +CC(C(=O)NCC(=O)N1CCc2ccccc21)c1ccsc1 +COc1cc2ccccc2c(Br)c1C(=O)N(C)C +CCNC(=O)CNC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +CCc1nc(COC(=O)COc2ccc(C)cc2)cs1 +CC(C)OCCC(=O)N(C)CCc1ccc(F)cc1 +c1ccc2oc(CNc3cncc(-n4cccn4)n3)cc2c1 +O=C(NCCc1ccc2ccccc2c1)c1ccc[nH]1 +Nc1cccc(-c2nn3c(-c4ccccc4)nnc3s2)c1 +Cc1cc(N2CCCCC2)nc(NCCNC(=O)c2cnccn2)n1 +O=C(NCc1ccccc1Cn1ccnc1)C1Cc2ccccc2S1 +COC(=O)c1ccoc1COC(=O)c1csc(-c2cccs2)n1 +CCN(Cc1cccc(NC(=O)NCc2ccccc2C)c1)C(C)=O +Cc1cc2nc(C)c(CCC(=O)Oc3ccccc3F)c(C)n2n1 +CCNc1ccnc(N(C)CCN2CCCCC2=O)n1 +CC(CNC(=O)NCc1ccc(C(=O)N(C)C)cc1)N1CCOCC1 +CC(C)N1CC2(CCCN(c3cc(N)nc(N)n3)C2)CCC1=O +COc1cc(CNC(=O)c2ccccc2C)cc(OC)c1OC +O=C(NCCc1ccccn1)C1CC1c1ccccc1Br +Cc1cc(OCC(=O)Nc2cccc(C(=O)NC3CC3)c2)no1 +C#CCNC(=O)c1ncc(Br)cc1Br +O=C(c1cscn1)N1CCCC(S(=O)(=O)NC2CCCC2)C1 +CC(=O)Nc1ccc(OCC(=O)Nc2cc(C)cc(C)c2)cc1 +Cc1c(C)n(CCCO)c2ncn3nc(-c4ccccc4)nc3c12 +CC(C)c1noc(CCCC(=O)N(C)c2cccc3ncccc23)n1 +COC(=O)C(NCc1cccc(C(N)=O)c1)C(C)(C)C +Cc1c(Cl)cccc1NS(=O)(=O)c1ccccc1N +Cc1cc(C)cc(C(=O)N2CCN(C(=O)N3CCOCC3)CC2)c1 +CCCc1nc(NCCSc2nnc(C)s2)c2cnn(C)c2n1 +COc1cccc(NC(=O)C(C)Sc2ccccn2)c1 +NC(=O)c1cccc(S(=O)(=O)Nc2ccc3c(c2)CCC3)c1 +CCC(=O)Nc1ccccc1C(=O)N1CCCCCC1 +COCCCNC(=O)c1ccc(Cn2cncn2)cc1 +CS(=O)(=O)c1ccccc1C(=O)N1CCC(CC(N)=O)CC1 +O=C(CNC(=O)c1ccc(N2CCCC2=O)cc1)NCC1CCCO1 +CCCOc1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1OC +CCn1ccc(C(=O)NCCOc2ccc(F)cc2)n1 +Nc1cc(N)nc(SCC(=O)c2cc(F)ccc2F)n1 +CC(NCc1ccccn1)C(=O)c1ccc2c(c1)CCCN2 +COC(=O)CNC(=O)C(C)Oc1ccc(Br)cc1 +CCCn1cccc1C(=O)N1CCCCC1CCO +COc1ccccc1NC(=O)NC1CCN(c2ccccc2)C1=O +O=C(CNC(=O)CC12CC3CC(CC(C3)C1)C2)NCc1cscn1 +CNC(=O)c1cc(Cl)ccc1NCc1csc(C)n1 +Cc1cc(C2CCCN2C(=O)c2cc3ccccc3[nH]2)no1 +COCCN(C(C)=O)c1nc(COc2cc(C)ccc2F)cs1 +CC(C)c1cncnc1N1CCOC(c2ccc(Cl)cc2)C1 +COC(CNC(=O)c1cn(C)nn1)c1ccc(C)s1 +CNC(=O)c1cccc(NCC(=O)Nc2cccc(Cl)c2C)c1 +COC(=O)c1ccc(OCc2cccc(F)c2)c(OC)c1 +Cc1noc(C2(C)CCCN(C(=O)c3cccnc3)C2)n1 +N#Cc1ccccc1NCCC(O)c1ccc(F)cc1 +O=C(C1CCOCC1)N1CCC2(CC1)CC(Oc1ccccn1)CO2 +COc1ccc(C)cc1NC(=O)c1cnc2n(c1=O)CCS2 +COc1ccc(-c2nnc(SC)o2)c(OC)c1 +CCCn1c(C)cc(C(=O)COc2ccc(C#N)cc2OC)c1C +COCCC(C)NC(=O)NCC(C)(O)c1ccc(F)cc1F +COCCc1ccc(OC(=O)C2CC=CCC2)cc1 +COCCCC1CCCN(c2cc(C3CC3)ncn2)C1 +CCOc1ccc(CCC(=O)N2CC3CC(C)OC3C2)cc1 +COc1ccc(C)cc1S(=O)(=O)NCC(C)(O)c1cccs1 +CCSc1cc(C(=O)Nc2ccc(C#N)c(Cl)c2)ccn1 +Cc1cc(=O)n2nc(NC3CCN(S(C)(=O)=O)CC3)sc2n1 +CC(Cc1ccccc1F)NC(=O)c1ccc(S(N)(=O)=O)o1 +C=CCNC(=O)Nc1ccc2c(ccn2CC(C)C)c1 +CN(C)C(=O)C1CC=CCC1C(=O)Nc1ccc(Cl)c(Cl)c1 +O=C(C1CC(=O)N(C2CC2)C1)N1CCN(c2ccccc2)C(=O)C1 +COc1cc(OC)c2cc(C(N)=O)[nH]c2c1OC +O=C1CN(C(=O)c2cscn2)CCN1Cc1ccc2c(c1)OCO2 +N#Cc1c(N)n(CCc2ccccc2)c(=O)c2cccnc12 +CC1(C)Cc2ccccc2-c2nnc(SCC(N)=O)n21 +Cc1ccn2cc(C(=O)N3CCN(c4ccccc4F)CC3)nc2c1 +O=C(NCCc1cc(F)cc(F)c1)c1ccn(-c2ccccc2F)n1 +O=C(c1ccc2c(c1)OCCO2)N1CCC(CO)C1 +COc1ccc(Nc2nc(OC)nc(OC)n2)c(OC)c1 +CN(C(=O)c1ccn(C2CCCC2)n1)c1cccc2ncccc12 +CCN1CC(CN(C)C(=O)c2cc(C3CC3)[nH]n2)Oc2ccccc21 +CNc1ccc(C2CN(S(=O)(=O)c3cn[nH]c3)CCO2)nc1 +O=C(NCCc1nnc2n1CCCCC2)c1cccc2ncccc12 +CCn1c(=O)n(CCC(C)C)c(=O)c2c3c(cnc21)C(=O)CCC3 +O=C(CNC(=O)NCc1ccc(F)cc1)Nc1nccs1 +Cc1ccc(N2C(=O)c3[nH]nc(C)c3C2c2cccnc2)cc1 +COCCc1cc(NC(=O)c2cn(C)nc2-c2cccs2)n(C)n1 +CCC(=O)N1CCCC(C(=O)Nc2cn[nH]c2)C1 +CCCC(Nc1c(N)c(C)nn1C)c1cccs1 +Cc1ccsc1C(=O)C1CCCN(Cc2cnn(C)c2)C1 +Cc1n[nH]c(C)c1NC1CCSc2ccccc21 +CCC1CCCCN1C(=O)CC1Sc2ccccc2NC1=O +O=C1OC(C(=O)Nc2ccc(Cl)cc2F)Cc2ccccc21 +NC(=O)C1CCN(C(=O)CCCSc2ccc(Cl)cc2)CC1 +CCCc1c(C(=O)NCC)cnn1-c1ccccc1Cl +CNS(=O)(=O)c1ccc(C)c(C(=O)NC(C)Cn2ccnc2)c1 +CCN(CC)C(=O)NCCc1nnc(SC)n1C +NC(=O)c1ccc2nc(-c3ccc(F)cc3)oc2c1 +NC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccccc1 +COc1c(F)cc(NC(=O)CCn2c(=O)oc3ccccc32)cc1F +CN1CCN(C(=O)c2ccnn2C)c2cccnc21 +Cc1cc(CNC(=O)c2cccc(NC(=O)c3ccco3)c2)c(C)o1 +COc1ccc(-c2c(CO)nnn2CCCO)cc1 +COc1ccc(S(=O)(=O)N2CCC(Cn3cccn3)CC2)cc1C +COC1CCCC1OC(=O)C1CCCN(C(=O)c2cccs2)C1 +CC1CC1C(=O)Nc1ccc(S(=O)(=O)N2CCCCC2)cc1 +Cn1ncc(C(=O)NC(C)(C)c2cccc(Cl)c2)c1N +Cc1c(NC(=O)NCc2ncc[nH]2)cnn1-c1cccc(Cl)c1 +CCc1nn2c(=O)cc(COC(=O)c3ccsc3)nc2s1 +Cc1csc(CNc2ccc(C)c(NC(=O)C(C)(C)C)c2)n1 +Cc1cc(C(=O)N(C)CC(C)(CO)CO)cc(C)c1F +COc1ccc2c(-c3cc(C4CC4)nc(N)c3C#N)n[nH]c2c1 +CCS(=O)(=O)N(C)CCOc1ccc(OC)cc1 +CN(C)c1ccc(NS(=O)(=O)c2ccc(F)cc2F)cn1 +Cc1ccc(CC(=O)Nc2ccc(Cl)c(C(=O)NC3CC3)c2)s1 +O=C(NC(Cc1ccccc1)C1CC1)c1cn(-c2ccccc2)nn1 +COC(=O)c1ccc2c(c1)nnn2Cc1ccccc1C +CCc1cccc(NC(=O)CCC(=O)N(C)Cc2cnccn2)c1 +O=C(Cn1nc(-n2cccn2)ccc1=O)NCCc1ccc(F)cc1 +Cc1nnc(-n2nc(-c3ccccc3)cc2-c2ccccc2)n1N +CCNC(=O)N1CCC(NC(=O)Nc2ccc3c(c2)CCC3)C1 +CCOCCNC(=O)Cn1c(C2CCCCC2)nc2ccccc21 +Cc1c(C(=O)NCc2ccoc2)oc2c(C)cccc12 +COCCNC(=O)CNC(=O)c1cccc(C)c1 +Cc1ccc(NC(=O)COCC2CC2)cc1S(C)(=O)=O +Cc1nn(C)c(C)c1NC(=O)Cc1csc(-c2cccs2)n1 +COc1ccc(-n2ncc(C(=O)C3CCN(C(C)=O)C3)c2N)cc1 +CCNc1oc(COc2ccccc2C)nc1C#N +N#Cc1cccc(CN2CCN(S(=O)(=O)c3ccccc3)CC2)c1 +CCOc1nc(N)c(Br)cc1Br +O=C(CNS(=O)(=O)c1ccccc1)OC1CCCCC1 +Cn1c(COC(=O)c2ccc(C(N)=O)nc2)nnc1-c1ccccc1 +Cc1ccc(C)c(C(=O)Nc2ccc(C(=O)NCCO)cc2)c1 +CCCCc1nnc(SCC(=O)Nc2ccccc2)n1C +Cc1ccc(NC(=O)CCc2ccco2)c2[nH]ncc12 +Cc1nc(-c2ccn[nH]2)cn1-c1ncc(C(F)(F)F)cc1Cl +O=C(NCc1nnnn1-c1ccc(F)cc1)Nc1cccs1 +CCN(CC)c1ccc(C(=O)N2CCN(CCOC)C(=O)C2)cn1 +O=C(Nc1nnc(C2CC2)s1)c1ccc(C(F)(F)F)cc1 +O=C(Nc1ccccc1)NC1CN(c2ccccc2)C1=O +Cc1ncccc1C(=O)N1CCOC(Cc2ccc(F)cc2)C1 +O=C(NC1CC1)C1CCCN1C(=O)Nc1ccc(F)cc1Cl +Cc1nn(C)c2ncc(NC(=O)NC(C)c3ccc(F)c(F)c3)cc12 +O=C(c1cccc(Cl)c1)N1CCCN(C(=O)C2CCCCC2)CC1 +O=C(Cc1noc2ccccc12)Nc1cc(N2CCCC2)ncn1 +CCOC(=O)CN(C(=O)c1ccc(C#N)c(C)n1)C(C)C +NC(=O)C1CCN(C(=O)CCSc2ccccc2F)C1 +O=C(CNc1ccccc1)c1ccc2c(c1)CCC2 +NC(=O)CCn1nc(-c2cccs2)c2c1CCNC2 +CCn1cc(CCC(=O)N2CCC(C)CC2)c(C)n1 +Cc1nn(C)c2sc(C(=O)Nc3cc(F)c(F)c(F)c3)cc12 +CC(NC(=O)c1n[nH]c(=O)c2ccccc12)c1ccc(F)c(F)c1 +O=c1c2ccccc2n(Cc2ccccc2)c(=O)n1CC1CCCO1 +CC(OC(=O)CNC(=O)C1CC1)c1cc(F)ccc1F +Cc1cccc(NC(=O)CSc2nc3ccccc3n3cnnc23)c1 +CC(C)Oc1ccc(NC(=O)NCCCN2CCOCC2)c(F)c1 +Cc1cc(NC(=O)c2cc3ccccc3c(=O)[nH]2)c2ncccc2c1 +c1csc(CN(CC2CCCO2)c2nccn3cnnc23)c1 +C=CCOC1C2CCC1N(C(=O)Cc1ccc(F)cc1)C2 +Cc1cc(F)ccc1NC(=O)c1cncc(Br)c1 +Cc1ccc(CN2CC(C)OC(C(N)=O)C2)c(Br)c1 +CCC(OC)C(=O)Nc1ccc(OC2CCCC2)cc1 +CCCN(CC(=O)OCC)C(=O)c1cccs1 +Cc1csc(SCc2nc(-c3cccs3)no2)n1 +COc1ccc(Br)cc1C(=O)Nc1ccccn1 +N#Cc1nnn(-c2ccc(S(N)(=O)=O)cc2)c1C(F)(F)F +CCOc1ccc(NC(=O)c2ccc(C)nc2)c(C)c1 +Cc1cc(C)c(C)c(S(=O)(=O)Nc2cnn(C)c2)c1C +CCN(C(=O)CN(C)S(=O)(=O)c1ccc(F)cc1)C1CC1 +COC(=O)c1cnc(N2CCCCC2)nc1C1CC1 +CC(=O)N1CCN(CCNC(=O)NCc2ccco2)CC1 +O=C(NC1CCN(C(=O)C2CC2)CC1)c1ccccc1F +Cc1cnc(C2NCCc3ccc(C)c(F)c32)cn1 +Cc1ccc(-c2ccsc2C(=O)N2CCC(C(N)=O)CC2)cc1 +CN(Cc1cnn(-c2ccccc2)c1)Cc1nc(C2CC2)no1 +CC(OCc1ccccc1)C(=O)Nc1ccc2ccccc2n1 +CN(C(=O)CN1CCN(C2CCOC2=O)CC1)C1CCCCC1 +Cc1cc(C)n(-c2nnc(SCC(N)=O)c3ccccc23)n1 +CC1(C)CNC(=O)c2nc(-c3ccccc3-n3ccnc3)[nH]c2C1 +O=c1[nH]c(Cn2nc3ccccn3c2=O)nc2sc3ccccc3c12 +CCN(CC)S(=O)(=O)c1cccc(C(C)=O)c1 +CCN(CC(O)c1ccc(C)cc1)C(=O)CCc1cn(C)nc1C +O=C(Nc1cccnc1)c1nn(-c2ccc(Cl)cc2)ccc1=O +CC(=O)Nc1ccc(F)c(NC(=O)NCC(C)N2CCOCC2)c1 +CNc1nnc(-c2cnn(-c3ccc(C)cc3C)c2C)s1 +Cc1cc(NC(=O)Cc2ccc(F)cc2)ccc1C(=O)N(C)C +CC(=O)NC(C(=O)Oc1ccc2c(c1)CCC(=O)N2)C1CCCC1 +O=C(c1cscn1)N1CCC2C1CCN2c1ncccn1 +COc1ccc(Cl)cc1-c1cc(NC(=O)c2nccnc2N)[nH]n1 +Cc1ccc(Nc2ccc(NCCNC(=O)C3CCCC3)nn2)nc1 +Cc1sc(CCNc2cn[nH]c(=O)c2Cl)nc1-c1ccccc1 +Cc1n[nH]c(C)c1S(=O)(=O)NCC(O)c1cccs1 +CCc1nc(CC(=O)Nc2cc(C)ccc2F)cs1 +CCOc1ccccc1NC(=O)Nc1nnc(-c2csc(C)n2)o1 +CCOc1ncccc1CNC(=O)NC(C)c1ccc(C)o1 +Cc1ccc(S(=O)(=O)NCC(=O)c2ccccc2)s1 +CCCC(=O)N1CCC(OC(=O)c2csnc2C)CC1 +COc1ccc(Br)cc1C(=O)CCC(=O)NC(C)C +Cc1cc(C)n(-c2ccc(=O)n(CCNC(=O)c3ccccn3)n2)n1 +CCCOC1CCCN(C(=O)C(CCC)NC(N)=O)C1 +COc1ccc(-c2noc(CCc3cnn(C)c3)n2)c(OC)c1 +Cc1cc(CN(C)C(=O)Nc2nnc(C(C)(C)C)s2)no1 +CC(C)c1cccc2c1OCCC(CO)(CO)C2=O +COCC1CCN(C(=O)c2cn(Cc3ccc(Cl)cc3)nn2)C1 +CCCn1ncc(C(=O)NCCCn2ccnn2)c1C +Cc1nc2cc(C(=O)Nc3cc(F)c(F)c(F)c3)ccc2[nH]1 +Nc1nnc2scc(-c3ccc4c(c3)OCCO4)n12 +Cc1noc(CNC(=O)c2ccc(OCC(F)F)nc2)n1 +CC(=O)N1CCc2cc(C(=O)NCCc3ccco3)ccc21 +Cc1cccc(C(=O)Nc2ccc3c(c2)OCCO3)c1N +COc1ccc(N(CC(=O)Nc2ccccc2)S(C)(=O)=O)cc1 +CCC(C)c1ccc(-c2cc(=O)c(C#N)c[nH]2)cc1 +CCN(CC)C(=O)CCC(=O)N1CCCC(C(=O)NC)C1 +COc1ccc(CC(=O)OCC(=O)Nc2ccc(F)cc2)cc1 +C#CCOC(=O)C1CC=CCC1c1nc2ccccc2s1 +CC1(C)CN(C(=O)NCc2cccs2)CCC1(C)O +Cn1c(SCC(=O)N2CCCC2)nnc1-c1cccnc1 +Cc1nn(-c2ccccn2)c2c1-c1nc(-c3ccncc3)ncc1CC2 +Cc1ncncc1C(=O)NC(C)c1nc2ccccc2[nH]1 +Cc1cccc2[nH]c(C3CCN(C(=O)c4cccnn4)CC3)nc12 +O=C(Nc1cccc2cn[nH]c12)C1(c2cccc(Cl)c2)CC1 +Cn1cc(NC(=O)NCc2ccccc2OC(F)(F)F)cn1 +N#CC(CCC(=O)Nc1ccccc1)c1ccco1 +COc1cccc(C(=O)N2CCCN(c3ncccc3C#N)CC2)c1 +Cc1cc(C(=O)Nc2nc(-c3ccc(F)cc3)cs2)n(C)n1 +COCc1ccccc1C(=O)Nc1ccc(N(C)C(=O)OC)cc1 +CN(C)C(=O)Cc1ccc(-c2ccc(NC(=O)N(C)C)cc2)cc1 +COc1ccc(C)cc1C(O)CNCc1ccc(C)cc1 +C=CCNC(=O)CSc1nnc(-c2cc3c(s2)CCC(C)C3)o1 +Cc1nnc(SCc2nc(-c3ccc(Cl)cc3)no2)n1N +O=C(CCc1ccc(O)cc1)NCCc1ccc(O)cc1 +O=C(NCc1ccccn1)C1CCCN(C(=O)C2CC2)C1 +Cc1csc(CNC(=O)C2CCCN(c3cnccn3)C2)n1 +O=C1CCC(CC(=O)N2Cc3cnn(Cc4ccc(F)cc4)c3C2)N1 +CCN(CC)C(=O)CCC(=O)Nc1ccccc1C(=O)N(C)C +Cc1ccccc1CN(CCO)C(=O)c1c(Cl)c(C)nn1C +Clc1cccc(-c2noc(C3CC4CCC3O4)n2)c1 +CCOc1ccc2c(=O)n(Cc3ccc(C#N)cc3)ccc2c1 +Cc1ccc2[nH]nc(C(=O)N(C)Cc3ccc(-n4cccn4)cc3)c2c1 +CC(C)N(C)C(=O)C1CCCN(C(=O)Nc2ccncc2)C1 +COc1ccc(C(O)CNC(=O)c2ccnc(-n3ccnc3)c2)cc1 +CC(C)CCN1CC23C=CC(O2)C(C(=O)N2CCNC(=O)C2)C3C1=O +CCCc1nc(C(NC(=O)OC(C)(C)C)C2CC2)no1 +NC(=O)NCC(=O)Nc1ccc(-c2csnn2)cc1 +Cc1nc(C)c(-c2nnc(SCc3nnnn3C3CC3)o2)s1 +CCn1nc(C)cc1NC(=O)c1cc(NC(=O)c2ccco2)n(C)n1 +CCN(CCO)C(=O)Cc1ccc(OC(F)(F)F)cc1 +CC(C)c1nc(CSc2ncc(C#N)c(N)n2)cs1 +CCN(CC)C(C)(C(=O)OC)c1cccc(F)c1 +CCCc1[nH]nc(O)c1C1OC(=O)c2c1ccc(OC)c2OC +Cn1c(=O)n(CCCO)c(=O)c2c3c(sc21)COC(C)(C)C3 +CCn1ccnc1SCc1csc(-c2ccc(C(N)=O)cc2)n1 +COC(=O)c1ccc(CSc2nnc(Cn3cncn3)o2)cc1 +Cc1nnc(NC(=O)CCn2cnc3sc(C)c(C)c3c2=O)s1 +CCOc1cc(CNC(=O)C2CC3C=CC2C3)ccc1OC(F)F +Cc1ccc(NC(=O)c2ccc(-n3cnnn3)cc2)nc1 +COc1cc(OC)cc(C(=O)Nc2c(C)cccc2C(C)C)c1 +Cc1nn(-c2ccccc2)c(C)c1NC(=O)COc1ccccc1O +CN(C)C(=O)c1cc(S(N)(=O)=O)c(OC2CC2)cn1 +COCCNc1ccc(CNC(=O)NC2CCC(O)CC2)cc1 +COc1ccccc1Cc1nc(-c2cn(-c3ccccc3)nn2)no1 +O=C(NCc1nccs1)c1ccc2cc[nH]c2c1 +Cc1nc(C)c(CNC(=O)Cc2ccc(C#N)cc2)s1 +CCc1onc(C)c1NC(=O)C(NC(=O)OC)C(C)C +CCOC(=O)C(C)NC(=O)CNC(=O)c1ccoc1C +CC(C)(C)OC(=O)N1CCCCC2CC(=O)CCC21 +Cc1cc(C)c(C#N)c(N2CCN(c3ncccn3)CC2)n1 +CCOCC1CCCN(c2cncc(Br)c2)C1 +CN(CC1COc2ccccc2O1)C(=O)Cc1noc2ccccc12 +Cc1cc(C)cc(NC(=O)NCCNS(=O)(=O)c2ccccc2)c1 +COc1ccccc1N1CCN(CC(=O)Nc2ccccc2C)C1=O +CCc1ccc(S(=O)(=O)Nc2cccc(CO)c2)cc1 +N#Cc1cc(-c2ccncc2)n(Cc2ccccc2)n1 +CN(C)C(=O)CCNS(=O)(=O)c1ccc(F)cc1F +COC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(OC)c(OC(C)C)c1 +CC(C)C(=O)N1CCC(C(=O)OCc2ccccc2)CC1 +O=C(NCC1CCCO1)C(c1ccccc1)c1ccccc1 +O=C(NCc1ccc(OCC2CC2)cc1)c1cccn2nccc12 +CNc1snc(C)c1C(=O)Nc1ccc(NC(=O)NC(C)C)cc1 +Cc1noc(CNC(=O)c2ccc3ccccc3n2)n1 +CC(C)(C)c1noc(CCC(=O)Nc2cccc3cn[nH]c23)n1 +CC(=O)c1cccc(NC(=O)CSc2nc(C)c(C)n2C2CC2)c1 +CCN1CC(C(=O)N2CCN(Cc3ccncc3)CC2)CC1=O +N#CC(C(=O)c1ccccc1NC(=O)c1cccs1)c1ccccn1 +COc1ccc(-c2cc(C(=O)N3CCCCC3)ccn2)cn1 +Cn1ccnc1C(NC(=O)CCn1cncn1)c1ccccc1 +CC1C(=O)Nc2ccc(-c3csc(NC4CC4)n3)cc21 +COCCn1c(=O)[nH]c2cc(C(=O)NCCNC(C)=O)ccc2c1=O +CCc1n[nH]c(C2CN(C(=O)c3c(C)nsc3NC)CCO2)n1 +CCC(C)C(=O)Nc1c(C(=O)N(C)C)nn(C)c1C +CCC(NC(=O)c1cc(N)cn1C)c1cccs1 +CCOCC1CCCN(C(=O)Cc2cccc(C(F)(F)F)c2)C1 +CC(C)(C)CC1CCCN1C(=O)CCC(=O)Nc1nccs1 +COc1ccc(-c2cn(Cc3ccc4c(c3)CCCO4)nn2)cn1 +COC(=O)NCC(=O)N1CCN(Cc2ncccc2C)CC1 +COC(=O)CCNC(=O)c1cc(=O)[nH]c2ccccc12 +COc1cc2c(cc1OC)CN(C(=O)NCCc1ccsc1)CC2 +CCOC(=O)C1=C(C)Nc2nnnn2C1c1ccc(C(=O)OC)cc1 +O=C(c1ccc(Br)cn1)N1CCC2CCCCC2C1 +CCOC(=O)c1c(C)nc(N)nc1COc1ccccc1 +CC(C)(C)c1nnc(NC(=O)CCSc2ccccn2)s1 +Cc1cc2c(c(C)c1Cl)C(O)C(N1CCC(=O)CC1)CO2 +CC1=C(C(N)=O)C(c2ccccc2F)n2nc(C)nc2N1 +CC(C)N(C(=O)CCOCC1CCCO1)c1cccc(C#N)c1 +CCSc1ccc(NC(=O)c2cnc(C)cn2)cn1 +Cc1ccc(S(N)(=O)=O)cc1C(=O)NCCCn1cccn1 +Cc1occc1CN(C)C(=O)C(NC(=O)c1ccccc1F)C(C)C +COc1ccc(C(=O)NCCS(=O)(=O)N2CCOCC2)c(O)c1 +COCCOc1ccccc1NC(=O)c1cc(C)sc1C +CCOc1ncccc1CNC(=O)N(C)Cc1cccc(C#N)c1 +Cc1cc(COc2cccc(C(=O)N(C)C)c2)no1 +Cc1ccn(CCC(=O)NC(C)c2cc(=O)n3nc(C)cc3[nH]2)n1 +Cc1ccc(-c2noc(COc3ccccc3OCCO)n2)cc1F +Cc1nc(C(C)C)ncc1C(=O)N1CCC2(CCNC(=O)CC2)CC1 +O=C(N1CCc2ccccc21)C1(c2ccccc2)CCOCC1 +Cc1cc(C(=O)NCC(C)N2CCOCC2)on1 +O=S(=O)(NC1CCCCCC1)c1cccc(O)c1 +CCCOC(=O)c1cc(-c2sc(-c3ccncc3)nc2C)n[nH]1 +C=CCCOCCNC(=O)N1CCOCC1C1CC1 +CCC(C)C(=O)CSc1cc(OC)c(OC)cc1C +CCN(CCO)S(=O)(=O)c1ccc(C(=O)NC)cc1 +N#CC(NC(=O)c1cccc(-n2cccn2)n1)c1cccc(Cl)c1 +O=C(c1ccco1)c1coc2ccc(OCC(=O)N3CCCC3)cc12 +O=C(NC1CCCC1)c1ccc(C(=O)NC2CCCC2)s1 +Cc1cccc(S(=O)(=O)CC(=O)NC2CCCCC2C)c1 +Nc1ccn(CCCSc2ccc(F)cc2F)n1 +O=c1[nH]c2ccccc2n1CCOc1ccc2c(c1)CCC2 +Cc1cccc(NC(=O)Cn2cnc(-c3ccccc3)cc2=O)c1C +Cc1cnc(=O)n(CCNc2ccccc2Br)c1 +CCN(CC)C(=O)c1sc(NC(=O)c2ccc(C)o2)c(C#N)c1C +CS(=O)c1ccc(C(=O)NCC(C)(C)C(N)=O)cc1 +C=CCOc1ccc(-c2nc(-c3ccc(C#N)cn3)no2)cc1OC +Cc1cc(C(=O)N2CCC3(CC2)Nc2cccnc2-n2cccc23)on1 +Cc1sc2[nH]c(CCC(=O)NCC(F)(F)F)nc(=O)c2c1C +c1nc(Oc2ccc3c(c2)OCO3)c2sccc2n1 +COc1ccc(F)c(NC(=O)C(C)Oc2ccc(C#N)cc2)c1 +O=C1CC(NC(=O)c2cccc(Br)c2)CN1 +CC(C)CC(=O)NCCn1nc(C2CC2)n(-c2ccccc2)c1=O +CN(Cc1csc2ccccc12)C(=O)CCOCC1CCCO1 +CCCCS(=O)(=O)N(C)Cc1ccc(C(N)=O)cc1 +Clc1ccc(C2CC(c3cccnc3)Nc3nnnn32)cc1 +CCc1nnc(CN(C(=O)Cc2c(C)n[nH]c2C)C(C)C)o1 +COC1CCCCC1NC(=O)NC1CCCCC1 +COC(=O)CNC(=O)c1nc(-n2nc(C)cc2C)ccc1Cl +O=C(CNC(=O)c1cccc(F)c1)Nc1nccs1 +Cc1occc1COC(=O)CN(C)S(C)(=O)=O +Cc1ccc(CCSc2nc(C)c(CCO)c(=O)[nH]2)cc1 +CCNC(=O)N1CCN(Cc2nnc(-c3cccs3)o2)CC1 +CCc1noc(CC)c1CC(=O)NCCc1cc(F)ccc1F +CN(CCN1CCOCC1)c1nc2ccccn2c1C#N +NC1=NC(=O)C(Cc2ccc(F)cc2)(c2cccc(Cl)c2)N1 +c1cc(Oc2nc3ccccc3o2)cc(-c2nnco2)c1 +COCCN(Cc1ccc(C#N)cc1)Cc1cnc2nc(C)cc(C)n12 +CC(C)COC(=O)N1CCCN(C(=O)c2n[nH]c3ccccc23)CC1 +CSc1ccc(CN(C)C(=O)CCC(=O)c2ccccc2)cc1 +O=C(NCCc1nnc2ccccn12)C1CC=CCC1 +CCCCNC(=O)C1CCN(C(=O)C2CCCC2)CC1 +CCOc1ccc(F)c(C(=O)Nc2cccnc2OC(C)C)c1F +COc1cc(N2CCN(CCO)CC2)ccc1N +Cc1ccc(OC(=O)COCc2nc(C)no2)c(Br)c1 +COCCn1nc(C)c(CNC(=O)NC2CCCCC2(C)C)c1C +O=C(Cn1cnnn1)N1CCN(Cc2cccs2)CC1 +CC(Sc1n[nH]c(=O)n1C)C(=O)NCc1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)C2CC(=O)N(C)C2)cc1S(C)(=O)=O +O=C(Nc1ccc(C(=O)N2CCCC2)cc1)NC(C1CC1)C1CC1 +CCCn1nc(C)c(-c2cncn2CC(C)n2nc(C)cc2C)c1C +CCN(CC)S(=O)(=O)c1ccc2c(c1)NC(=O)CN2C +Brc1cnc(N2CCOCC2)c2[nH]ccc12 +NS(=O)(=O)CCNC(=O)CCCc1cccc(Br)c1 +Cc1ccccc1-c1cc(NC(=O)NCc2cnn(C)c2C)n(C)n1 +CCCCc1nnc2sc(-c3cccc(N)c3)nn12 +CCc1cccc(CC)c1NC(=O)c1ccc(NS(C)(=O)=O)cc1 +C=CCNC(=O)c1cnc2c(c1)c(C#N)cn2Cc1ccccc1 +Cc1cnc(C(=O)Nc2cccc(C(F)(F)F)c2)cn1 +COc1ccc2ccn(Cc3noc(-c4ccoc4)n3)c(=O)c2c1 +Fc1cccc(-c2n[nH]c3c2CN(Cc2ncccn2)CC3)c1 +CCN(CC)C(=O)NCc1ccc(NC(=O)NC(C)C)cc1 +O=C(NCCc1ccccn1)Nc1cc(F)cc(N2CCCC2)c1 +O=C(NCC1CCCO1)C1(c2ccccc2F)CCCC1 +CCc1cccc(NC(=O)N2CCc3[nH]c4ccnn4c(=O)c3C2)c1 +CCOCc1nnc(NC(=O)c2ccnc3ccc(Cl)cc23)s1 +CC(C)N(CCO)S(=O)(=O)c1ccc(C(N)=O)cc1 +CC(C)N(C)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +C=CCN1CCC2CN(C(=O)C(C)C)CC2C1=O +CNC(=O)c1cccc(OC(=O)Cc2ccccc2C)c1 +CSc1ccccc1C(=O)Nc1ccc(-n2cncn2)cc1 +O=C(c1cnn2ccccc12)N1CCCCC1CCc1ccc(O)cc1 +C=C(C)CN(CC)C(=O)NC(C)C(=O)N1CCCCC1 +O=C1NCCN1c1ccc(NCc2cncs2)cc1 +CC1CCCC(C)N1C(=O)CNc1ccc(C#N)cc1 +CCOC(=O)C(C)Oc1cccc2c(=O)n(CC(N)=O)ccc12 +Cc1ccc(OCCc2ncc(C#N)s2)cc1C +Cc1ccc(OCCNS(=O)(=O)c2ccc(C#N)cc2)cc1 +CC(=O)NCc1nnc2c3ccccc3c(-c3ccccc3)nn12 +CN(C)C(=O)C1(CNC(=O)Cc2ccc(F)cc2F)CCCC1 +Cc1nc2ccccn2c1C(=O)NCCc1ccncc1 +CC1CCCN(S(=O)(=O)N(C)C(C)c2cc(F)ccc2F)C1 +O=C(COc1cccc(F)c1)Nc1cc(F)ccc1F +N#CCc1cccc(C(=O)Nc2cccc(Cl)c2)c1 +COc1ccc(NC(=O)c2cccc(F)c2)cc1OC +CCCc1nnc(NC(=O)Cc2n[nH]c(=O)c3ccccc23)s1 +Cn1c(=O)c2c(-c3ccccc3)cc(-c3cccs3)nc2n(C)c1=O +COc1ccc(Br)c2c1C(CN(C)C)NCC2 +Cc1n[nH]cc1CNC(=O)C1(c2ccccc2)CC1 +Cc1ccc(CNS(=O)(=O)c2ccc3c(c2)n(C)c(=O)n3C)cc1 +CCCc1nn2c(=O)cc(COC(=O)c3ccccc3F)nc2s1 +COC(=O)c1c(O)cc2oc(=O)cc(C)c2c1O +CC(C)Oc1ccc(NC(=O)c2ccc(Cn3ccnc3)cc2)cc1 +Cc1nn(C)c2nc(NC3CCN(C)C3=O)sc12 +CC(C)n1cc(CN(C)C(=O)c2cc(-c3ccncc3)n[nH]2)cn1 +Cc1nc2ccc(C(=O)N3CCCCC3CC(N)=O)cc2nc1C +CCOC(=O)c1csc(NC(=O)C2CCCN2S(C)(=O)=O)n1 +CNC(=O)c1cccc(NC(=O)CCc2ccc(OC)cc2)c1 +COCCCNC(=O)c1cc(=O)c2cc(N)c(C)c(C)c2o1 +O=C(OCC1CC1)c1cccc(OCC(F)F)n1 +O=C(NCCc1ccccn1)c1cccc2nscc12 +CCC(=O)N1CCCC(C(=O)N2CCC(Cc3nc(C)no3)CC2)C1 +COc1cc(S(=O)(=O)N(C)C)c(OC)cc1Br +CN(CC1CCOC1)C(=O)c1cc(F)ccc1F +CCN(Cc1cn(CC)nc1C)S(=O)(=O)c1ccc(OC)cc1 +CC1Oc2ccccc2OC1C(=O)OCC(=O)c1ccccc1 +Cc1nn(C)c(C)c1OS(=O)(=O)c1ccc(C(N)=O)cc1 +COC(=O)C1Oc2c(O)cccc2C1C(=O)OC +C#CCN(CC(C)C)c1c(N)n(CC(C)C)c(=O)[nH]c1=O +Cc1cnc(-n2nnc(C(=O)NC3CC3)c2C)s1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)c1cn2cccnc2n1 +N#Cc1cc(NCc2cnn3ccccc23)ccc1F +COc1cc(OC)cc(-c2nccn2Cc2ccc(C#N)cc2)c1 +COCC(C)NC(=O)c1ccn(-c2ccc(F)cc2)n1 +Cc1nc2ccc(NCC(=O)N3CCOCC3)cc2s1 +COC(=O)c1cc(NC(=O)c2ccc3nnc(C)n3c2)cc(C)c1C +N#Cc1ccc(NCC2CCN(c3ccc(F)c(F)c3)C2)nc1 +Cc1cc(C(=O)NCC(=O)Nc2cn(C)c(=O)cc2C)c(C)o1 +COc1ccc(CC(=O)NC(C)c2nc(C)no2)cc1 +CC1C(=O)NCC2CN(S(=O)(=O)c3ccccc3F)CC21 +O=C1CN(C(=O)CCCOc2ccccc2)CCN1 +COC(=O)C(C)CNC(=O)Nc1ccc(CC#N)cc1 +Cc1oc(C(=O)N2CCCc3cc(F)ccc32)cc1S(N)(=O)=O +CC(C)CN(C)C(=O)c1cc(Cl)c2c(c1)OCCCO2 +Cc1noc2nc(C3CC3)cc(C(=O)NC(C)c3ccncc3)c12 +CC(Nc1nccc(CCC(F)(F)F)n1)c1ccncn1 +CCOc1cccc(NC(=O)c2ccnc(N)c2)c1 +CC(C)c1nccn1Cc1cccc(NC(=O)Nc2cn[nH]c2)c1 +Cc1c(NC(=O)CNC(=O)c2cccs2)c(C(=O)N(C)C)nn1C +CCNC(=O)c1cccc(CNC(=O)N(C)CC2CC2)c1 +Cc1nnc(SCc2cccc(Br)c2)n1N +O=C(Nc1cccc(NC(=O)C2CC3C=CC2C3)c1)c1ccco1 +CS(=O)(=O)NCc1nnc(C(=O)Nc2ccccc2)s1 +Cc1n[nH]c(C)c1NC(=O)C(C)Oc1ccc(Br)cc1 +Cc1cccc(C(C)C)c1NC(=O)c1ccccn1 +CC(C)(C)CC(=O)Nc1cc(-c2ccncc2)n[nH]1 +Cn1ccc(NC(=O)c2cc(C(F)(F)F)nn2C)n1 +CC(C)(O)CCc1ccc(C(=O)NC2CCCNC2=O)cc1 +CC(O)Cc1nsc(NC(=O)c2cccc(Cl)c2)n1 +COC(=O)c1ccc(NC(=O)C2CN(C(=O)c3cc(C)on3)C2)cc1 +Cc1ccc(F)c(CN(C)C(CCO)c2ccccc2)c1 +Cc1nc(CC(=O)OCc2cn3cccc(C)c3n2)cs1 +CC(=O)NC1CCCN(C(=O)NCC2(c3ccccc3F)CC2)C1 +Cc1nc(Cn2c(N)nc3cc(F)ccc32)cs1 +CCc1ccc2c(c1)C(=O)CC2CC(=O)N1CCN(C)CC1 +COC(=O)c1ccc(NS(=O)(=O)c2ccccc2C#N)cc1 +CCCNc1nc(C)nc2onc(C(=O)OCC)c12 +CN(Cc1ccccc1Br)C(=O)Nc1nccs1 +O=C(NCCOCC(F)(F)F)Nc1cccc(C(F)(F)F)c1 +CCOc1cc2c(cc1NC(=O)NC(C)CC)OC(C)C2 +O=C(NCc1nc(C2CC2)no1)c1cccc(F)c1F +Clc1ccccc1NCc1cnn(-c2ccccc2)c1 +Cc1nc(-c2ccccc2)sc1CNC(C(N)=O)c1ccccc1 +CC(NCCN1CCOCC1)c1cccc(Br)c1 +COc1cnc(-c2ccccn2)nc1-c1ccccc1 +CCCS(=O)(=O)N1CCN(C(=O)c2ccc(C)c(F)c2)CC1 +N#CC(CC(=O)N1CCc2ccccc2C1)c1ccco1 +O=C(NCCc1nc2ccccc2[nH]1)c1ccco1 +CCC1CCCC(NC(=O)NCCCCN2CCOCC2)C1 +CCc1cnc(CN(C)C(=O)c2cnc(C3CCCO3)s2)s1 +CCN(Cc1ccc(OC)cc1)S(=O)(=O)N1CCCCCC1 +CN1C(=O)Cc2cc(C(=O)NCc3cccs3)ccc21 +CCCc1cnc(N2CCN(CC(=O)Nc3ccccc3)CC2)nc1 +CC(C)(C)OC(=O)N1CC(Oc2ncccc2F)C1 +CC1CCCCN1S(=O)(=O)N1CCCC1C1CCCC1 +CN(CC(=O)N=c1sccn1C)C(=O)c1ccco1 +O=C(NCc1cc(F)ccc1F)c1cccc(OCC(F)F)n1 +NS(=O)(=O)c1ccc(Cl)c(C(=O)NCCc2nccs2)c1 +Cn1nccc1CNc1ccccc1CN1CCNC1=O +Cn1cc(CNc2cccc3c2CCCC3)c(-c2ccncc2)n1 +CC1COC(c2ccccc2Cl)CN1C(=O)Cc1ccc[nH]1 +COCCNc1nc(-c2cc(C)c(C)cc2OC)ccc1C#N +CCC(C)(C)NS(=O)(=O)c1cc(-c2cnc(C)o2)ccc1C +Cc1cc(C)n(CC(C)CNC(=O)c2csc(C)n2)n1 +COc1ccc(C(=O)CNC(=O)Cc2cccc(F)c2F)cc1 +CC1CCN(C(=O)Nc2ccc(C(=O)N3CCCCCC3)cc2)CC1 +CC(C)Oc1ccc(C(N)C(F)(F)F)cc1Cl +O=C1C(=O)N(CCS(=O)(=O)c2ccccc2)c2ccc(F)cc21 +CC(C)c1nc2sc(CCOc3ccccc3)nn2c1CO +O=C(CCc1ccccc1)NCCc1ccsc1 +COc1ccc(NC(=O)c2ccccc2)c(OC)c1 +CC(CN1CCOCC1)C(=O)c1ccc(F)cc1 +O=C(NCCCn1cccn1)N1CCN(c2cnccn2)CC1 +O=C(NCc1cccnc1)c1nnc(-c2cccnc2)o1 +NC(=O)c1ccc(C#CCNC(=O)c2ccc3ncsc3c2)cc1 +COc1ccc(S(=O)(=O)NCCc2cccs2)cc1 +O=C(N1CCCC1)N1CCOC2(CCCC2COc2cccnc2)C1 +COc1ccc(CNc2c(C#N)cnn2C)cc1F +CCN1CCN(Cc2ccc(C#N)cc2)C(=O)C1=O +CC(C(=O)N(CC(N)=O)C1CCCC1)n1ccnc1 +COc1cc(OC)c(NC(=O)c2c(F)cccc2F)cc1F +Cc1cnc(NC(=O)CN2C(=O)C(C)(C)c3ccccc32)s1 +Cn1c(COc2ccccc2)nnc1SCc1ccc(C#N)cc1 +COc1ccccc1OCC(=O)Nc1ccc2nc(C)sc2c1 +Cc1nn(C)c(C)c1C(C)NC(=O)N(C)Cc1cc(Cl)cn1C +CCn1cnnc1C1CCCN(C(=O)CCc2ccc(OC)cc2)C1 +CC(C)(C)c1nnc(SCC(=O)NCC(F)(F)F)n1N +CC(C)(C)C(O)CNC(=O)c1ccc(N2CCCCC2)cc1 +FC(F)Oc1ccc(NC2CCN(CC(F)(F)F)C2)nc1 +COC(=O)CCn1c(=O)c2c(nc3oc(C(C)(C)C)cn32)n(C)c1=O +CCOCCC(=O)Nc1ccc(Cl)cc1C(=O)OC +O=C(Nc1nc2ccccc2s1)N(Cc1ccco1)C1CC1 +O=C(CNC(=O)c1ccc(C(F)(F)F)cc1)Nc1ccncc1 +FC(F)(F)c1ccccc1CNc1cnccn1 +COc1ccccc1OCC(=O)N1CCn2cccc2C1C +Oc1ccc(CNc2ccc3cn[nH]c3c2)cc1F +Cc1ccc(CC(=O)OCc2nnnn2-c2ccccc2)cc1 +CC1CCCC(N(C)C(=O)c2ccc3ccccc3n2)C1 +COC(=O)C(C)NC(=O)c1ccc(O)c(Cl)c1 +CN(Cc1ccc(C#N)cc1)C(=O)c1c[nH]c2cccc(F)c12 +Nc1ccccc1NC(=O)c1nc2ccccc2[nH]1 +COc1ccc(-c2nnc3ccc(C)nn23)cc1N +CN(C)S(=O)(=O)N(CCO)c1ccc(F)cc1F +COC(=O)NCc1nc(-c2ccnc(OC)c2)no1 +CCOc1ccccc1NC(=O)c1cc2ccccn2n1 +O=C(OCc1cccc2c1OCCO2)C1CC=CC1 +CN(C)c1ccc(C(=O)Nc2ccc(F)c(Cl)c2)cn1 +COc1cccc(C2NC(=O)c3sc4nc(C)cc(C)c4c3N2)c1 +Cc1cc(C(=O)CCC(=O)NC(C)C)c(C)s1 +CCn1c(N)nc2cc(C(=O)N3Cc4ccccc4C3)cnc21 +O=C(NCc1cccs1)C1CCN(C(=O)c2ccco2)CC1 +Cc1cc(Br)cc(-c2n[nH]cc2N)c1F +CCn1nc(C)cc1C(=O)NCc1ccnc(OC2CCC2)c1 +CN(Cc1ccsc1)C(=O)Cn1c(=O)cnc2ccccc21 +CCN(C)C(=O)COc1cc(F)ccc1C(C)O +CCCc1noc(C2CCN(C(=O)CCc3ccccc3)CC2)n1 +CCOC(=O)c1n[nH]cc1C1CC(NC(C)=O)CC(CC(C)C)O1 +CCCNC(=O)CN(C)C(=O)Cn1cc(C(F)(F)F)ccc1=O +COc1cccc(OCCNC(=O)c2ccc(C(C)=O)s2)c1 +CC(=O)c1ccc(NC(=O)Cc2c(C)nn(CC(C)C)c2C)cc1C +CCc1ncc(C(=O)N(C)CC2CCCCO2)cn1 +O=C(CCc1cccnc1)N(Cc1ccc(F)cc1)C1CC1 +NS(=O)(=O)c1ccc(CCn2ccnc2-c2ccccn2)cc1 +C=CCNC(=O)c1cc(S(=O)(=O)Nc2ccc(F)cc2)ccc1C +CCOC(=O)C(Cc1cccc(C#N)c1)C(O)C(F)(F)F +CCCn1cnc2cc(NC(=O)CC3CCN(C(C)=O)CC3)ccc21 +Cc1nc(CNc2cccc(Cl)c2)sc1C +CCn1nccc1C(=O)Nc1nnc(-c2ccn(C)n2)o1 +COc1cc(CNCc2csc(C(C)(C)C)n2)ccn1 +CC1(NC(=O)NCc2ccnc(OC3CCC3)c2)CCC1 +O=C1Cc2cc(C(O)COc3ccccc3)cc(F)c2N1 +CC(C)N1CN(n2cnnc2)c2nc3ccccc3n2C1 +Cc1ccc(CC(=O)Nc2ccc(NC(N)=O)cc2)cn1 +NC(=O)c1cccc(Nc2c(-c3ccccc3)nc3cnccn23)c1 +CNC(=O)NCC(=O)N(C)C(C)Cc1ccc(C)cc1 +Cc1ncsc1C(=O)N(C)C(C)c1cccc(N)c1 +O=C(CC(O)C(Cl)(Cl)Cl)Oc1ccccc1 +COc1ccc(NC(=O)c2cc3nc(C)ccc3o2)cc1 +COc1ccc(-c2cn(CCS(=O)(=O)N3CCCC3)nn2)cn1 +COCc1csc(NC(=O)c2cccnc2OCC(F)F)n1 +COc1ccc2c(c1)CCN2C(=O)c1ccncc1 +CCc1ccc(-n2cnnc2)cc1NC(=O)NCC1(O)CCCCC1 +CCc1noc(CC)c1CC(=O)N(CC)Cc1cccc(F)c1 +O=C(c1ccc[nH]1)N1CCN(c2nccc(C(F)(F)F)n2)CC1 +COCc1ccccc1CNC(=O)NC1CCCc2c1cnn2C +Cc1n[nH]c2ncc(C(=O)NCC3CCOC3)cc12 +O=C(CCC(=O)c1ccc2c(c1)CCC2)Nc1cccc(O)c1 +CN(Cc1cc(-c2ccncc2)no1)CC(C)(C)N1CCOCC1 +Cc1cc(C)nc(SCC(=O)NCc2ccccc2Cl)n1 +Cc1cc(C(N)=O)ccc1NC(=O)c1c2c(nc3ccccc13)CCC2 +CCc1ccc(-c2n[nH]c(SCCN3CCOC3=O)n2)cc1 +CC(C)C(=O)N1CCCC1C(=O)NCCN1CCOCC1 +Cn1cnnc1SCC(=O)c1cc(F)ccc1F +CCOC(=O)c1noc(C)c1COc1ccc(F)cc1F +N#Cc1ccc(-n2ccnc2C(=O)NC2CC2)cc1 +COc1ccccc1COC(=O)C1CCN(C(=O)C2CC2)CC1 +COC(=O)c1ccc(F)cc1NCC1CCC=CO1 +Cc1cc(C)c(NCC(O)c2cccs2)c(C)c1 +COc1cccc(C(CO)Cc2ccc(OC)c(OC)c2)c1 +COc1cc(C#N)ccc1OCC(=O)N1CCNC(=O)C1 +Cc1cc(C)n2ncc(C(=O)NC(C3CC3)C3CC3)c2n1 +C=CCCOC(C)C(=O)N1CCc2ccccc2C1CC +CC(C)N1CCOC2CN(C(=O)c3ccn(C)n3)CC21 +CNS(=O)(=O)c1ccc(Cl)c(C(=O)N2CC(C)OCC2C)c1 +CCN(CCO)S(=O)(=O)c1c(C)nn(C)c1C +CCOC1CCCN(C(=O)c2sccc2-n2cnnn2)C1 +C#CCNC1CCc2ccc(OC(=O)N(C)CC)cc21 +CCc1ccccc1NC(=O)CCS(=O)(=O)c1ccc(C)cc1 +CCc1ccc(C(=O)N2CCN3C(=O)C(CO)NC(=O)C3C2)cc1 +COCCOC(=O)C(C)n1c(=O)oc2cccc(N)c21 +COC(=O)c1cn(C(=O)c2ccco2)c2ccccc12 +CC1CCC2=C3CCC(C)CC3c3c(c(=O)c3=O)C2C1 +CCc1cc(=O)[nH]c(-c2cccc(NC(=O)c3ccsc3)c2)n1 +CC(C)CS(=O)(=O)Nc1ccc2c(c1)CCC(=O)N2C +CCN(CC)C(=O)C(C)N1CCN(Cc2cccs2)CC1 +O=C1c2cc(Br)ccc2CC12CCC2 +O=C(C1CCc2ccccc21)N1CCC(OCc2cccnc2)CC1 +COc1ccc(C)cc1NC(=O)c1ccc(C)nc1N +CNC(=O)CN(c1ccc(C)cc1C)S(C)(=O)=O +O=S(=O)(c1ccc(-c2cc(O)n[nH]2)cc1)C1CCCC1 +Cc1ccc(C(=O)OCC(=O)N(C)C2CC2)n1C +CC(C)(C)OC(=O)N1CCC(CCOc2cnccn2)CC1 +CCNC(=O)CNC(=O)c1ccc(NC(=O)c2ccco2)s1 +O=C(C1CC12CCC2)N1CCc2c(ncnc2N2CCOCC2)C1 +Cc1ccc(C(=O)CCC(=O)NC2CCCC2)cc1 +COc1ccc(Oc2ccc(Cl)cn2)c(N)c1 +O=c1ccc2ccccc2n1Cc1nnc(-c2cccnc2)o1 +Cc1ccc(NCc2cc(F)c(F)c(F)c2)cc1S(C)(=O)=O +CS(=O)(=O)NCC(=O)N1CCC2C(CCC(=O)N2CCCO)C1 +CCc1nn2c(=O)c(CC(=O)OC)c(C)[nH]c2c1-c1ccccc1 +O=C(NCCCn1cccc1)c1cc(-c2ccc3c(c2)OCO3)n[nH]1 +Cc1ccc(OC(=O)CNS(=O)(=O)c2ccc(C)cc2)cc1 +C=CCSc1ccccc1NS(=O)(=O)c1ccc(C(N)=O)cc1 +Cc1ccc(NC(=O)c2[nH]c3c(c2C)C(=O)CCC3)c(C)c1 +CCOCCC(=O)Nc1ccc2[nH]c(CN3CCOCC3)nc2c1 +COCCCC(=O)N(Cc1ccc(C)s1)C(C)C +CN1CC(NC(=O)c2cc(-c3cccc(Cl)c3)no2)CC1=O +Cc1noc(C(NC(=O)NC2(C)Cc3ccccc3C2)C(C)C)n1 +CCOC(=O)Cc1cn2cc(Br)ccc2n1 +CN1CCN(C(=O)CSc2nc3ccccc3n(C)c2=O)CC1 +COCC(=O)N1CCCC(c2nc(C)cc(Nc3ncccn3)n2)C1 +Cc1ccc(NC(=O)C2C(C)(C)C2(C)C)cc1S(C)(=O)=O +COC(=O)C(NC(=O)c1cccc(-n2cccc2)c1)C(C)C +COc1ccc2cc(S(=O)(=O)n3nc(C)cc3C)ccc2c1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)NC(C)CN1CCOCC1 +Cc1n[nH]c(C)c1N1CCN(C(=O)C2CCC2)CC1 +CNC(=O)c1ccc(NCCCOc2ccc(C#N)cc2)cc1Cl +Cc1nnc(SC(C)C(=O)c2ccccc2)s1 +CCCS(=O)(=O)N(C)c1ccc(NC)c(C)c1 +Cc1cc(S(C)(=O)=O)ccc1NC(=O)C1CC2CCC1O2 +O=C(c1cc(-c2ccco2)[nH]n1)N1CCCC1c1ccncc1 +Cc1cc(C(=O)Nc2nc(-c3ccco3)cs2)ccc1F +Cc1cccc(OCCC(=O)Nc2ccc3c(c2)oc(=O)n3C)c1C +CCC(=O)Nc1nc(-c2ccc3c(c2)CCO3)cs1 +O=C(Cc1cn2ccsc2n1)Nc1ccccc1Br +CC(C)COc1ncc(CNC(=O)CC(C)C)cc1Cl +CCNc1cc2c(nn1)CCN(C(=O)c1ccc(-c3cnco3)cc1)C2 +C#CCN1CCC(C(=O)Nc2ccc(-c3nc(C)cs3)cc2)CC1 +CC(C)c1ncc(N)c(C(=O)Nc2cnn(C)c2)n1 +CN(C)S(=O)(=O)c1cc(NC(=O)c2cccs2)ccc1Cl +Cc1ccc(C(=O)CSc2nnnn2C(C)C)c(C)c1 +COCc1c(CO)nnn1-c1ccc2c(c1)OCO2 +Cc1cc(C(=O)NC2CCc3nnc(C)n3C2)no1 +COC(=O)c1ccc(NCC(=O)c2cccc(N)c2)cc1 +Cn1c(N2CCOC(Cn3cccn3)C2)c(C#N)c(=O)n(C)c1=O +CC(=O)N1CCCC2(C(=O)N(C)C)CN(c3ncccn3)CC2C1 +Cc1nn(Cc2nc(C3CCOC3)no2)cc1Cl +Cc1noc(CCC(=O)Nc2ccc(C(C)C)cc2)n1 +CC(C)(C)OC(=O)N1CCC(C#N)(c2ccccc2)CC1 +COc1ccc(C(=O)Nc2cnc(N3CCOCC3)nc2)cc1 +CCc1cnc(N2CC3OCC(COc4ccc(C)nc4)C3C2)nc1 +Clc1ccc2c(c1)CN(CCOCC1CCCO1)CC2 +C=CCN(Cc1ccc(C)s1)C(=O)C(N)c1ccccc1Cl +Cc1ccnc(NS(=O)(=O)c2cccc(N)c2)c1 +N#Cc1cc(NC2CCC(O)CC2)ccc1C(F)(F)F +CCN(CC)S(=O)(=O)N1CCC(=Cc2cccc(F)c2)CC1 +CN(Cc1ccccc1N1CCOCC1)CC(F)(F)F +Cc1cc(C)cc(-n2nnnc2SCc2nc(C(C)C)no2)c1 +Nc1ccccc1C(=O)N1CCC2CCCCC2C1 +CSc1cccc(NC(=O)CC(NC(C)=O)c2cccs2)c1 +O=C(NCCNC(=O)C1CC1)Nc1cccc(F)c1 +CN(CCC#N)S(=O)(=O)c1cc2c3c(c1)CC(=O)N3CCC2 +CCC(=O)Nc1nnc(S(=O)(=O)N(CC)c2ccccc2)s1 +Cc1ccc(S(C)(=O)=O)cc1NC(=O)c1ccccn1 +CCc1ccccc1NC(=O)CSc1nncn1C(C)C +COc1cccc(C(=O)N2CCn3cnc(COCC4CC4)c3C2)c1 +CNc1nc2c(Br)cc(F)cc2s1 +CCC(OC)C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCC3 +Cc1csc(C2(NC(=O)NCCN3CCOCC3)CCC2)n1 +NC(=O)CC1CCN(C(=O)c2ccccc2F)CC1 +Cc1n[nH]c(C2CCCN(C(=O)OC(C)(C)C)C2)n1 +Cc1nc(CSc2nnc(-c3ccccc3)n2C)oc1C +CNc1c(N)n(-c2ccccc2OC)c(=O)[nH]c1=O +COC(=O)c1cn(NC(=O)c2ccncc2)c(=O)c2ccccc12 +CCCc1nc(NC(C)(C)C)c(N)c(OCC)n1 +COc1cccc(OC)c1C(=O)c1ccnc(C)c1 +CC(=O)NC(C)C(=O)Nc1ccc(CCN2CCOCC2)cc1 +CC(CCc1ccccc1)NC(=O)C1CC(=O)N(C(C)C)C1 +Cc1cc(NC(=O)COC(=O)c2ccc3c(c2)OCO3)no1 +CCOCC1COCCC12CCN(C(=O)c1cccnc1OC)CC2 +C=CCCOC(C)C(=O)Nc1ccc(NC(N)=O)cc1 +Cc1ccc(CNC(=O)c2ccc3c(c2)CCN3)s1 +O=C(NCCCS(=O)(=O)N1CCc2ccccc2C1)c1ccco1 +CCC(CC)C(=O)Nc1ccc2sc(NC(C)=O)nc2c1 +CC1COCCN1C(=O)Cc1csc(Cc2ccccn2)n1 +CCOC(=O)c1ccc(Nc2ccc(S(=O)(=O)N(C)C)cn2)cc1 +Cn1cccc1C(=O)N1CCC2C1CCN2S(C)(=O)=O +CC1CCCCC1NC(=O)c1cc2ccccc2oc1=O +CC(=O)NCCCCCC(=O)N1CCOC(c2ccccc2)C1 +Cc1noc(COC(=O)COc2ccc(F)c(Cl)c2)n1 +COc1ccc(Cl)cc1CNC(=O)C(CC(C)C)NC(N)=O +CCCc1nc(Cn2c(CO)nc3ccccc32)cs1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)NC1CCCCC1O +N#Cc1ccc(NC(=O)NC2CN(c3ccccc3)C2=O)cc1 +O=C(Nc1nc2c(s1)CCCC2)c1ccc2c(c1)OCCCO2 +Cc1nc(-c2ccc(F)cc2)sc1C(=O)N(C)C +O=C(NCC(O)c1ccoc1)c1cc(-c2ccccc2)on1 +COc1cccc(C(=O)Nc2cc(C)nn2-c2nc3ccccc3[nH]2)c1 +CCCNC(=O)CNC(=O)NCC(C)(C)c1ccccc1 +N#Cc1ccc(Sc2nnc(-c3ccc[nH]3)o2)nc1 +CCCc1cc(C(=O)OCC)c(NC(=O)c2cccnc2)s1 +CCNC(=O)C(C)Oc1ccc(Cl)cc1Cl +Cc1cc(=O)oc(C)c1C(=O)OC(C(=O)N(C)C)c1ccccc1 +COc1cc(N)c(NC(=O)c2ccc(C)c(C)c2)cc1OC +CCc1cc(NC(=O)C(C)c2cccs2)n(C)n1 +CCNC(=O)NC(c1ccccc1)c1ccccc1 +CN(C)C(=O)c1n[nH]c2c1CN(Cc1cccs1)CC2 +Cc1cccc(CNC(=O)CCn2cnc3oc(C)c(C)c3c2=O)c1 +O=C(NCc1ccc(OCC(F)(F)F)nc1)c1ccccc1 +CCN(C(=O)c1cccc2[nH]ncc12)C(C)COC +Cc1nc(-c2cccc(NC(=O)N3CCCC4CCCC43)c2)n[nH]1 +Cn1cncc1Cn1ccc(-c2cccc(-c3ccc(C#N)cn3)c2)n1 +COc1ccc(NC(=O)c2c(C)nc(C(C)(C)C)[nH]c2=O)cc1Cl +Cc1cc(C)c2nnc(SCC(=O)Nc3cccc(Cl)c3)n2n1 +CC1CCc2c(sc(NC(=O)CSc3ncn[nH]3)c2C#N)C1 +Cn1cc(-c2nc(C(=O)NCc3nnc4ccccn34)cs2)cn1 +O=C(CSc1ccc(F)c(F)c1)Nc1cccc2cn[nH]c12 +Cn1nc(COc2ccc(Cl)cc2Cl)cc1N +Cn1c(C2CC2)nc2cc(NC(=O)c3sccc3C#N)ccc21 +CC(=O)N1CCN(C(=O)Nc2cc(F)ccc2C)CC1 +CCC(C)OC(=O)C1CC=CCC1C(=O)NCC1CCCO1 +Cc1cc(C)c(C(=O)NCCc2ccncc2C)c(C)c1 +Cc1nc2nc(SCc3ccc(F)cc3C#N)nn2c(C)c1C +CCCCN(C)C(=O)c1onc(-c2ccc(Cl)cc2)c1N +CCC(C)n1nc(NC(C)=O)c2cc3cc(C)ccc3nc21 +CCCCOc1ccccc1NC(=O)c1cn[nH]n1 +COc1ccc(OC)c(S(=O)(=O)Nc2cccc(C)n2)c1 +COC(=O)C1CCCC(=O)N1c1cccc(OC)c1 +CC1CCC(C)N(C(=O)Nc2ccccc2N(C)S(C)(=O)=O)C1 +O=C(CSc1cn[nH]n1)NCc1cccs1 +CC(=O)c1cc(F)ccc1OCC(=O)Nc1ccccc1Cl +O=C(NCC1COCCO1)c1ccc(Br)cc1O +CCCSc1nnc(NC(=O)Cc2ccccc2)s1 +O=C(NCCCO)c1cccnc1SC(F)F +CCCn1nc(C(=O)Nc2sccc2C(=O)OC)ccc1=O +COc1ccc(C(CC(=O)Nc2nncs2)NC(C)=O)cc1 +O=C(NCC(=O)N1CCC(COc2ccccc2)CC1)C1CCCC1 +COCC(C)Nc1ncnc(Nc2ccc(Cl)cc2)c1N +CCC(C)C(=O)CSc1nnnn1-c1cccc(NC(C)=O)c1 +CCOCCOC(C)C(=O)Nc1ccc(N)cc1C +O=C(CCC(=O)N1CCOCC1)NCc1cnn(-c2ccccc2)c1 +Cc1csc(NC(=O)CCc2cnn(C)c2C)n1 +C=CCSc1nc2ccc(NC(C)=O)cc2s1 +CCOc1cc(C)ccc1NC(=O)c1cnn(-c2ccccn2)c1C +Cc1ccc(CN(C(=O)NCCC(=O)NC2CCCC2)C(C)C)o1 +O=S(=O)(c1cccc2ccccc12)N(CCO)CCO +O=C(NC1CCCCC1)C(O)c1ccc(Cl)cc1 +CCCCNC(=O)C1CCC(C)N(Cc2cnc(C(C)C)s2)C1 +CCN(CC)c1ncnc(Nc2ccc(Cl)cc2)c1N +CC(=O)Nc1ccc(F)c(NC(=O)Cc2ccc3ccccc3c2)c1 +CC(C(=O)N1CC=C(c2ccccc2Cl)CC1)n1cccc1 +COC(=O)C1=C(C)NC(=O)NC1c1ccccc1C(=O)OC +N#Cc1cc(CNc2ccn(-c3ncccc3Cl)n2)ccc1F +Cn1c(=O)c(C(=O)Nc2ccc(F)cc2Cl)nc2ccccc21 +CCc1ccccc1CNC(=O)N(C)Cc1cc(C)on1 +CC(Cc1ccccc1F)NC(=O)c1n[nH]c2c1CCC2 +CCC(OC)c1n[nH]c(=O)n1-c1ccc(C)cc1C +NC(=O)COC(=O)c1cccc(Oc2ccccc2)c1 +CC1CCN(C(=O)NCc2ccnc(-n3cccn3)c2)C(C)C1 +CC(C)C(=O)Nc1nnc(-c2ccc(Cl)c(N)c2)s1 +Nc1ccc(NC(=O)CCc2ccco2)c(Br)c1 +Cc1ccc(S(=O)(=O)N2CCN(CC3CC3)CC2)cc1Cl +CCN(C)C(C(=O)NCc1cccnc1OC)c1ccccc1 +COC(=O)CN(C(=O)c1cc(Cl)ccc1OC(C)C)C(C)C +CCc1nc(C2CCCN2C(=O)c2ccc3c(c2)OCO3)no1 +CC(=O)NC(C)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +COC(=O)NCC(=O)NC1(c2ccc(Br)cc2)CC1 +CSc1ccc(NC(=O)N(C)Cc2cc(C)on2)cc1 +COC(=O)Nc1cccc(NCc2nc(-c3cccc(C)c3)no2)c1 +Cc1c[nH]c(-c2ccc(F)c(Br)c2)n1 +NC(=O)c1cccc(CNC(=O)Nc2ccccc2Cl)c1 +O=C(Cn1ncc2ccccc21)Nc1cnn(-c2ccccc2F)c1 +O=C(C1CCCO1)N1CC2OCCN(c3cnccn3)C2C1 +CCOC(=O)c1ccc(NC2CCCN(c3ncccn3)C2)nc1 +Cc1cc(F)ccc1CCNC(=O)c1ccc2c(c1)OCCO2 +CC(C(=O)NC1CCCc2ccccc21)n1ccc(C(F)(F)F)n1 +CCOC(=O)N1CCC(NC(=O)c2ccc(C#N)cc2)CC1 +Cc1noc(CCC(=O)NC2(C)Cc3ccccc3C2)n1 +COc1cc(CC(=O)NC2CCC(C)CC2)ccc1C +COC(=O)C1CCCN(Cc2c[nH]nc2-c2ccc(OC)cc2)C1 +CC(C)Cn1c(SCC(=O)C2=NC=CC2)nc2ccccc2c1=O +CCc1cc2c(COC(=O)c3c(C)noc3C)cc(=O)oc2cc1O +CC(C)c1cc(Br)ccc1NC(=O)c1ccc(=O)n(C)c1 +O=C(NCc1csc2ccccc12)NCC1CCCC1O +O=S(=O)(c1cccnc1)N1CCC(Oc2cccc(F)c2)CC1 +CC(Sc1ccccn1)C(=O)Nn1cnc2ccccc21 +N#Cc1ccc(O)c(NC(=O)c2scnc2C2CC2)c1 +CC(C)NC(=O)NC1CC(C)NC(=O)N1C(C)C +Cc1ccc(S(=O)(=O)N2CCCN(C(=O)NC3CC3)CC2)cc1 +Cc1cccc(Oc2ncccc2NC(=O)NCCO)c1C +O=C(Cc1csc(Nc2ccc(Cl)cn2)n1)Nc1cccnc1 +Cc1cnc(C(=O)N2CCCCC2CCc2ccccc2)cn1 +CCC(C)N(Cc1ccncc1)C(=O)COc1ccccc1C +COc1ccc(CNC(=O)Cn2cc(C#N)c3ccccc32)cc1OC +CC(C)(C)OC(=O)Nc1ccc(C(=O)N2CCC2)c(O)c1 +Cc1c(CN2CCC3(C2)OCCO3)cc(C#N)n1C +Cc1nc(C)c(CC(=O)Nc2ccccc2Oc2ccccc2)c(=O)[nH]1 +Cc1cc(C)n(CCC(=O)NCc2ccc(C)o2)n1 +O=C(C1CCCO1)N(Cc1ccoc1)C1CCCCC1 +CN(C(=O)CCNS(=O)(=O)c1ccc(F)cc1)c1ccccc1 +CCC(NC(=O)c1cn(C)nc1C(C)(C)C)C(=O)OC +Cc1nc(CCC(=O)Nc2ccccc2CN2CCOCC2)cs1 +Cc1ccc(NC(=O)C2Nc3ccccc3S(=O)(=O)N2)cc1F +CCCC(=O)N1CCN(c2nc3c(F)cccc3s2)CC1 +Cc1n[nH]c(C)c1CCC(=O)N=c1[nH]c2ccccc2[nH]1 +Cc1n[nH]c(C)c1NC(=O)Nc1ccc(N2CCOC2=O)cc1 +CC(C)C(C)NC(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1n[nH]cc1C(=O)N1CCCC1c1cccc(-n2ccnc2C)n1 +c1ccc2c(-c3nn4c(-c5cnccn5)nnc4s3)c[nH]c2c1 +Cc1cnc(C(NC(=O)N2CCOCC2C2CC2)C2CC2)s1 +CCc1noc(C)c1C(=O)NC(C)CN1CCCC1=O +NC(C(=O)Nc1cc(Cl)cc(Cl)c1)c1ccccc1 +CCOc1ccccc1NC(=O)N1CCCC(C#N)C1 +CSc1nc2nnc(C(=O)N3CCN(C)CC3)c(C)n2n1 +Cc1ccc(C(C)NC(=O)NC2CCC(=O)N(C)C2)cc1F +CC(C)C(NC(=O)c1cccs1)C(=O)NC(C1CC1)C1CC1 +O=C(NC1CCCc2occc21)C1CCCCC1C(=O)N1CCCC1 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+O=C(Nc1ccccc1O)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +CC(=O)c1ccc(S(=O)(=O)NCc2ccc(C)s2)cc1 +COc1cc2ccccc2cc1C(=O)Nc1ccccc1C(N)=O +N#Cc1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 +Cc1csc(CCNC(=O)CNC(=O)C(C)(C)C)n1 +Cc1n[nH]c(SCC(=O)Nc2nc(-c3ccccc3C)cs2)n1 +CCc1nc(CC(=O)OC2CCCCC2OC)cs1 +CCCCc1nnc2sc(COc3ccccc3OC)nn12 +CCN(CC1CCCO1)c1cc(C)nc(COC)n1 +Cc1n[nH]c(C)c1CCC(=O)NCCc1cccc(F)c1 +O=C(CN1CCN(c2nccs2)CC1)NC(C1CC1)C1CC1 +CC(NC(=O)COc1ccccc1C#N)c1nnc2ccccn12 +CC(C)NC(=O)CN1CCN(CCOc2cccc(Cl)c2)CC1 +CCN(CC)C(=O)CCC(=O)N1CCCC1c1cccc(C)c1C +NC(=O)c1cccc(CCNC(=O)Cc2c(F)cccc2Cl)c1 +N#CCC1(COC(=O)c2cc(-c3cccs3)[nH]n2)CC1 +O=C(CCCOc1ccccc1)Nc1cccc(-n2cnnc2)c1 +Cc1csc(CNc2ncnc3ccccc23)n1 +Cc1nc2ccccc2c(=O)n1CC(=O)NC(C)CCc1ccccc1 +CCC1CN(Cc2ccc(C(=O)OC)c(F)c2)CC(C)O1 +NC(=O)c1oc2ccccc2c1NC(=O)c1cc(=O)c2ccccc2o1 +COC(=O)Cn1c(C(C)=O)nc2ccc(F)c(F)c21 +O=C1CC(c2ccccc2)N(c2nc3ccccc3s2)CCN1 +Cc1ccc(C)c(OCCN2C(=O)Cc3cc(N)ccc32)c1 +O=S(=O)(Nc1ccc(F)cc1)c1ccc(O)cc1 +COC(=O)c1cc(C#N)c(=O)n(CCCc2nc3ccccc3o2)c1 +OCCN1CCN(c2nncc(-c3ccccc3F)n2)CC1 +COC(C)(C)CNC(=O)NCc1ccn(-c2ccc(F)cc2)n1 +CC(C)n1nccc1NC(=O)CSc1ccccc1Cl +CCc1cc(C(=O)N2CCN(C(C)C)CC2)[nH]n1 +CCCC(=O)N1CCC(=O)N(Cc2ccc(F)cc2)C(C(C)C)C1 +CCCCS(=O)(=O)NCC#Cc1ccccc1N(C)C +Cc1noc(C)c1Cn1c(N)nc2cc(Cl)ccc21 +CCc1cc2ccccc2nc1SCC(=O)Nc1nonc1C +Cc1ccccc1NC(=O)c1nnn(Cc2ccc(Cl)cc2)c1N +Cc1nnc2n1CCN(Cc1ccc(OCc3ccccn3)cc1)C2 +O=C(CC1CCCC1)N1CCCN(C(=O)c2ccc(F)cc2)CC1 +O=C(CNC(=O)c1ccc(-n2cccc2)cc1)Nc1ccccn1 +COc1cccc(-c2cc(C(=O)Nc3ccc4[nH]ccc4c3)n[nH]2)c1 +CCn1cnnc1CNc1ncnc2sccc12 +CCc1cc(N)cc(C)c1NC(=O)c1ccc(OC)cc1 +CS(=O)(=O)c1cccc(N2CCN(Cc3cccnc3)C2=O)c1 +O=C(Nc1ccc(Cn2cncn2)cc1)c1cc(Cl)ccn1 +Cc1ccc(F)cc1C(=O)Nc1ccc2oc(=O)[nH]c2c1 +Cc1cc(C(=O)OCC(N)=O)c2c(C)nn(C)c2n1 +O=C(C1CC1)N(Cc1cccnc1)c1ccc(Cl)cc1 +CCC(C)C(NC(=O)C(C)C)c1nc(-c2ccco2)no1 +CC1CCN(C(=O)C(C)Sc2nnc(-c3ccccc3)n2N)CC1 +Cc1nn(CC(=O)NCCNc2cccnc2)c(C)c1C +Cc1cccc(OCC(=O)NCCc2ccsc2)c1 +CCc1nnc(CN(C)C(C)Cc2ccc(Cl)cc2)o1 +Cc1cccc(C(=O)Nc2n[nH]c(-c3ccco3)n2)c1 +CCC(=O)Nc1ccc(NC(=O)CNC(=O)CC(C)(C)C)cc1 +CNC(=O)CCNc1ccc(-c2ccccc2)cc1 +NS(=O)(=O)CCNC(=O)CCCc1ccc(Cl)cc1 +CC(C)CC(C#N)N(C)C(=O)c1ccc(C(F)(F)F)cc1 +CC(=O)Nc1cc(-c2ccco2)nn1-c1nc2c(c(=O)[nH]1)CCC2 +Cn1c(SCC(=O)Nc2ccccc2)nnc1-c1ccc(F)cc1 +COCCN(Cc1ccc(C)o1)C(=O)c1ccc(-n2ccnn2)cc1 +CC(C)(C(=O)NCC(=O)NC1CC1)c1ccc(Cl)c(Cl)c1 +COC(=O)C(C)(C)NS(=O)(=O)c1c(C)c(C)cc(C)c1C +C=CCCOC(=O)Cn1cnc2c(C)cccc2c1=O +COc1ccccc1C(C)NS(=O)(=O)c1ccccc1F +COc1ccc(CNc2nnc(-c3ccccn3)s2)cn1 +Cc1nc(COC2CN(c3ncccn3)C3CCCOC23)cs1 +CCC(C)OC(=O)CN1C(=O)CNc2ccccc21 +COc1cccc(CNc2nnnn2-c2ccccc2)c1 +O=C(Cc1cccc(O)c1)Nc1cccc2cn[nH]c12 +Cc1nc(CN(C)C(=O)c2cc(Br)cn2C)cs1 +O=C(NCC1CCN(C(=O)c2cccnc2)CC1)NC1CCCCC1 +COC(=O)c1c(C)[nH]c(C(=O)CN2CC(C)OC(C)C2)c1C +CC(=O)c1ccc(F)c(NC(=O)c2ccc(F)cc2)c1 +Nc1ccccc1OCCCc1nc(-c2ccncc2)cs1 +Cc1csc(NC(=O)c2cc(C)c3c(=O)n(C)c(=O)n(C)c3n2)n1 +O=C1COc2c(cccc2C(=O)Nc2cnn(-c3ccccc3)c2)N1 +CC(C)N1CC(C(=O)N(CC(=O)N(C)C)CC(F)(F)F)CC1=O +Cc1nc(C(=O)Nc2cccc(C(F)(F)F)c2)cs1 +NC(=O)Cn1c(=O)nc(N)c2c3c(sc21)CCCCC3 +O=C(CCc1cccs1)NCc1ccccc1CN1CCOCC1 +COCCNC(=O)C1Cc2ccccc2CN1C(=O)c1ccco1 +Nc1ncc(C(=O)NCC2CCCOC2)cc1Cl +CCN(C)S(=O)(=O)N1CCC(OCc2ccccc2C)CC1 +COc1ccc(-c2nnc(SCc3n[nH]c(=O)[nH]3)n2C)cc1 +CC(Cc1ccc(O)cc1)NC(=O)N(C)Cc1nccn1C(F)F +COc1cc(-c2noc(CCc3c[nH]c4ccccc34)n2)ccn1 +COC(CNC(=O)C(C)Sc1ccccn1)c1ccccc1 +CCS(=O)(=O)Nc1ccc2c(c1)CN(C(=O)C(C)C)CC2 +CCC(CC)N(CCO)C(=O)c1cc(F)cc(F)c1 +COc1ccc(NC(=O)NCCC(=O)Nc2nc(C)cs2)cc1 +Cc1ccc(C(=O)NC(C)(C)c2cnn(C)c2)c(F)c1 +CNC(=O)CNC(=O)c1cc2ccccc2c(N)n1 +COc1ccc(NC(C)=O)c(NCc2ccccc2)c1 +CCCS(=O)(=O)c1ccccc1NCC1CCOC1 +CC(C)c1ccsc1C(=O)Nc1ccc(Cn2cncn2)cc1 +COc1ccc(S(=O)(=O)NCCC(=O)N2CCOCC2)cc1 +CC(Sc1ccccn1)C(=O)Nc1cccc(N)c1 +Nc1cccc(-n2nnnc2CN2CCOCC2)c1 +CC(C)c1nnc(NC(=O)C2CC=CCC2)s1 +Cc1cccc(C(C)C)c1NC(=O)CCNC(=O)Cc1ccccc1 +O=C(NCc1cc(-c2ccc3c(c2)OCCO3)on1)c1cccs1 +COc1c(O)ccc2c1C(c1cncc(F)c1)NCC2 +Cc1ccoc1C(=O)N1Cc2cnn(Cc3ccc(F)cc3)c2C1 +COCCN(CC(=O)N(C)C)C(=O)c1cnn(-c2ccccc2)n1 +Cc1ccc(NC(=O)C2CC2)cc1NC(=O)NCC1CC1 +Cc1ccc(OCCc2nc(C)c(C#N)s2)cc1C +COC(=O)CCC(=O)N(C)Cc1cc(C)ccc1C +FC(F)(F)c1nnc2sc(Cc3noc4ccccc34)nn12 +C=CCN(Cc1cccs1)C(=O)c1cnc2ccccc2n1 +Cc1ccc(CC(=O)Nc2ccc(Cl)cn2)s1 +CC(C)CS(=O)(=O)N1CCCC1c1cccs1 +O=C(Nc1ccc(Br)cc1)c1cnn(-c2ccccc2)c1 +Cc1cc(C)n2nc(C(=O)NCc3cc4ccccc4o3)nc2n1 +COc1ccc(NC(=O)COc2ccccc2OC)cc1Cl +CCOC(=O)c1cc(-c2c(O)ccc3ccccc23)nn1C +Cc1nsc(NC(=O)N2CCC(Cc3ccccc3F)CC2)n1 +CC(=O)c1cccc(OCC(=O)Nc2cccc(C(N)=O)c2)c1 +N#Cc1ccc(NC(=O)COc2ccc(Oc3ccccn3)cc2)cc1 +CC(C)(CNC(=O)c1cc(Cl)c(O)c(Cl)c1)N1CCOCC1 +Cc1ccc(NC(=O)CSc2cn[nH]n2)cc1F +Cc1cc(NC(=O)Cn2nc(-c3ccc(F)cc3)ccc2=O)[nH]n1 +CC1CCCCC1NC(=O)c1ccc(Cl)c(N2CCCC2=O)c1 +COCCC(=O)N1CCC(c2cc(-c3cnn(C)c3)cc(C)n2)CC1 +CCOC(=O)c1c(NCc2cccs2)ccn1C +CCCCn1nc(C(=O)Nc2cccc(SC)c2)ccc1=O +C#CCNC(=O)CSc1nnc(-c2ccc(C)cc2)o1 +Cc1ccc(OCc2nc(C#N)c(NCC3CCCO3)o2)cc1 +CC(=O)Oc1ccccc1C(=O)N1C(C)CCCC1C +O=C(c1ccco1)N1CC2CCCN(C(=O)c3ccsc3)C2C1 +CCOC(=O)c1cnc2c(C(=O)OCC)cnn2c1 +CCOc1ncnc(Nc2cccc(Cl)c2C)c1N +Cc1cncc(C(=O)NC(C)c2cc(F)ccc2N2CCOCC2)c1 +CC(c1ccccn1)N(C)C(=O)Nc1ccccc1C(F)(F)F +CC(=O)c1cc2c(cc1NC(=O)C(C)(C)C)OCCO2 +CCc1cccc(OC2CN(C(=O)c3cc(C)no3)C2)c1 +O=C(c1cncc(C#CCO)c1)N(CCO)C1CC1 +CNC(=O)c1cc(OC)ccc1NC(=O)CC(C)(C)c1ccccc1 +Cc1ccc(C)c(N(C(C)C)S(=O)(=O)c2cn(C)cn2)c1 +O=C(CO)N1CCN(C2CCN(c3ccccc3F)C2=O)CC1 +CC(=O)c1cccc(S(=O)(=O)NC(C)Cc2ccco2)c1 +Cc1ccc(N2CC(NC(=O)N3CCC(C(N)=O)CC3)CC2=O)cc1 +CCNS(=O)(=O)c1ccc(NC(=O)N(C)C)cc1 +CCC(CC)N(C)C(=O)c1ccc2[nH]c(=O)[nH]c2c1 +COc1ccccc1C(O)CNC(=O)Nc1cn[nH]c1 +Cn1cc(CNC(=O)CCC(=O)N2CCOCC2)cn1 +CC(=O)c1ccc(NC(=O)c2cccc(SCC#N)c2)cc1C +CCN(CC)C(=O)c1cn2c3c(cc(Br)cc3c1=O)CC2 +CC(NC(=O)NCc1ncn(C)n1)c1cccc(Br)c1 +COc1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1 +Cc1ccc(CNC(=O)c2ccc(C)c(N3CCCC3=O)c2)cc1 +Cc1nc(CCc2ccccc2N)nc2c1CCCC2 +OCCSc1nnc(-c2c[nH]c3ccccc23)n1Cc1ccco1 +Cc1nc(NC(=O)N(Cc2ccccc2)CC2CCC2)oc1C +O=C(OCCNc1cccnn1)C1CC1c1cc(F)ccc1F +CS(=O)(=O)N1CCCC(C(=O)Nc2nccs2)C1 +O=C(Nc1ccc(F)c(F)c1)c1ncn(-c2ccc(Cl)cc2)n1 +Cc1nc(CN(C)C(=O)NCC2CCOC2)cs1 +O=C(c1cc[nH]n1)N1CCCn2nnc(Cn3cccc3)c2C1 +Cn1cnc(CNC(=O)NCC(C)(C)c2ccc3c(c2)OCO3)n1 +CCC1=NS(=O)(=O)c2cc(NC(=O)C3CC3)ccc2N1CC(C)C +CCN(CC)C(=O)CCC(=O)Nc1sc(C)cc1C(N)=O +CCn1nc(-c2ccc(OC)cc2F)cc1C(=O)N1CCCCC1 +CCNc1nn(-c2nc(C)cc(C)n2)c2c1C(=O)CCC2 +O=C(Cn1ccc(C(F)(F)F)n1)c1ccccc1 +CCCCCNC(=O)CSc1ncc(C#N)c(N)n1 +Cc1noc(C)c1C(C)NC(=O)c1ccc2c(c1)OCCO2 +Cc1cc(C)n2nc(C(=O)NCCSc3ccccc3)nc2n1 +CN(C)S(=O)(=O)c1ccc(CNCc2ccc(C#N)cc2)cc1 +CC(C)(CNC(=O)c1ccccc1O)N1CCOCC1 +NC(=O)C1CCCN1C(=O)COc1cccc(C(F)(F)F)c1 +CC(NC(=O)C(C)(C)C)c1ccc(-n2cncn2)cc1 +Cc1cc(C)c(C(=O)NCc2ncn(C)n2)c(C)c1 +Cc1csc(C2CCCN(Cc3cc(F)cc(F)c3)C2)n1 +Cc1ccc(S(=O)(=O)N(Cc2ccco2)c2ccccn2)cc1 +CC(C)(C)c1ncc(NC(=O)NCC(C)(O)c2ccc(F)cc2)cn1 +FC(F)Oc1cccc2c1CCNC2c1ccco1 +COC(=O)c1c(O)c(Cl)cc(Cl)c1Cl +CN(CC(N)=O)C(=O)c1ccccc1-c1ccccc1 +CCc1nn(C)cc1NC(C)C(=O)Nc1cccc(F)c1 +O=C(CNC(=O)c1ccnc2c1OCO2)NCc1cccs1 +O=C(NCCSc1ccccc1)c1cncc(Br)c1 +CC(OC(=O)c1cnn(-c2ccccc2Cl)c1)C(N)=O +COc1cccc(-c2nc(C(=O)N3CCOCC3C3CC3)c(C)[nH]2)c1 +Cc1cc(-c2cnc(N3CCCC(O)C3)nc2-c2ccco2)on1 +CCN(CC)C(=O)c1c(C)nc(N)nc1Cc1ccc(OC)cc1 +Cc1cccc(CN2CCN(C(=O)C3CC=CC3)CC2)c1 +CN(C)c1cc(OC2CCN(C(=O)c3ccnn3C)C2)ncn1 +Cc1nc(C)c(C(=O)Nc2ccc(N(C)C(C)C)c(F)c2)s1 +Cc1nnc(SCC(=O)Nc2ccccn2)n1Cc1ccccc1 +CCC1CNc2cc(S(=O)(=O)NCC(C)C)ccc2O1 +CN(C)c1ccc(-c2cc(C#N)nn2CC#N)cc1 +CC1CCCN(C(=O)CCn2c(=O)oc3ccccc32)C1 +Cc1ccccc1-c1nn2c(C#N)c(C)nc2s1 +CCCCNC(=O)C1CCCN(C(=O)c2cccc(NC(N)=O)c2)C1 +CC(C)OCCN1CCN(C(=O)CNC(=O)NC2CC2)CC1 +Cc1ccc(NC(=O)c2cc(=O)c(OCc3ccccc3)co2)c(C)c1 +CC(NC(=O)NCCN(C)c1ccccc1)C1CCCO1 +CCNC(=O)Nc1cccc(NC(=O)C(OC)c2ccccc2)c1 +CN(C)c1ccc(NC(=O)c2occc2COc2ccccc2)cn1 +CCCOc1nc(OCC(F)(F)F)ccc1N +CCCCNC(=O)CCC(O)c1ccc(C)c(N)c1 +O=C(OCCCc1ccncc1)C1CCCN1C(=O)c1cccs1 +COC(CNC(=O)N(C)C(C)c1ccncc1)c1cccc(Cl)c1 +COc1ccc(-c2cccc(C#N)c2)c(OC)c1OC +CCN(CC(=O)OC)C(=O)c1ccc(O)c(Cl)c1 +O=C(NC1CCN(C(=O)C2CCCC2)C1)c1scnc1C1CC1 +CCn1nc(C(=O)NCc2cccs2)c2ccccc2c1=O +CC(OC(=O)c1ccccc1F)C(=O)NC(C)(C)C +O=C(Cc1ccc(F)cc1F)Nc1ccc(NC(=O)C2CC2)nc1 +CCN(CC1CC1)C(=O)c1occc1CN1C(=O)Cc2ccccc21 +Nc1cncc(N2CCN(c3ccccc3)CC2)n1 +CC(C)Oc1ccc(-c2cc(N)nn2C)cc1Cl +Cc1ccc2nc(SCC(=O)Nc3cc(C)nc(C)n3)[nH]c2c1 +CCOc1ccc(-c2csc3nc(N)nn23)cc1Cl +CCOc1ccc(OCc2nc3cc4c(cc3[nH]2)OCO4)cc1 +O=c1n(Cc2ccccc2)nc2c(N3CCOCC3)nccn12 +COc1cccc(-c2cc(C#N)c(=O)n(CCC(C)C)n2)c1 +CCOc1ccc(OCC)c(CSc2nc(N)cc(=O)[nH]2)c1 +CC1CN(Cc2nc3ncccc3[nH]2)CCN1c1ccc2nncn2n1 +CCOC(=O)C1CCN(C(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)CC1 +CC1CCCC(CNC(=O)C2CC(=O)Nc3cc(F)ccc32)C1 +Cc1nnc(N2CCC(CS(N)(=O)=O)CC2)c(C#N)c1C +CC1CN(Cc2nc(-c3cccs3)no2)CC(C)(C)O1 +CC(C)N(Cc1cccc(Cl)c1)C(=O)c1cn[nH]c1 +CC(=O)c1ccc(NC(=O)COc2ccccc2Cl)cc1 +NS(=O)(=O)c1ccc(OCCC(=O)NCC2CCCC2)cc1 +CCCCCn1c(CNC(=O)c2ccncc2)nc2ccccc21 +CC(C)C(=O)N1CCN(C(=O)c2ccc3cnsc3c2)CC1 +COc1ccc(Cc2nn(CCO)c3c2C(=O)CCC3)cc1 +CC(=O)NC(C)(C)c1noc(COc2cccc3c2OC(C)(C)C3)n1 +Cc1c(C(=O)NC(C)C)oc2ccc3c(c12)C(O)CC(C)(C)O3 +OCc1cn(Cc2ccccc2)nc1-c1cccs1 +CCOc1ccc(NC(=O)COc2cccc(C(C)=O)c2)c(C)c1 +COc1cc(C(C)C)c(OC)cc1NCCN1CCOCC1 +CC(=O)N1CCN(C(=O)CN(C)c2ccc(C(C)(C)C)cc2)CC1 +O=c1[nH]nc2c(N3CCCCC3)nc3ccccc3n12 +O=C(NCCNS(=O)(=O)c1cccs1)C1CC1 +CCCNC(=O)C(C1CCCC1)N1CCN(C(=O)C2CCCC2)CC1 +CCN(CCO)c1ncnc(Oc2ccccc2OC)c1N +CCCS(=O)(=O)N1CCC2COC(CNc3ncccn3)C2C1 +CCN(Cc1ccccc1F)C(=O)c1nn(C)c2ccccc12 +CSc1nsc(NC(=O)c2ccc(C)cc2C)n1 +O=C(Cc1ccccc1NC(=O)c1ccn2ccsc12)NC1CC1 +O=C(Cn1c2ccccc2c(=O)c2ccccc21)NCCCO +CCOc1ccc(F)c(C(=O)NCC(=O)Nc2cccnc2)c1F +Cc1ccc(C(=O)NC(C(=O)NCCCO)C(C)C)cc1 +N#Cc1ccc(-c2noc(C3CC3c3cccc(F)c3)n2)nc1 +CC(C)NC(=O)CNC(=O)Nc1ccccc1Br +O=C(Nc1cccc(Cl)c1F)NC1CCN(CC(F)(F)F)C1 +Cc1occc1-c1nnc(SCC#N)n1-c1ccccc1 +CCN(C(=O)CN1CCOC(Cn2cncn2)C1)C1=CCCCC1 +COc1ccc(C(=O)NCc2ccc(C)cc2)c(OC)n1 +CN(CC1CCCC1)C(=O)c1ccc2[nH]nnc2c1 +CCOC(=O)c1sc2nc(SC)nc3c2c1NCN3 +O=C(COc1ccc(F)cc1)NCC(O)c1ccc2c(c1)CCO2 +CCOc1ccc2c(c1)S(=O)(=O)N=C(NC)N2 +CN1C(=O)CCC12CCC(NC(=O)c1ccc3c(c1)OCO3)CC2 +Cc1ccc(C(C)NC(=O)NC(C)Cc2c(C)nn(C)c2C)cc1F +Cc1cccc(C)c1NC1=Nc2cc(N)ccc2OC1 +Cc1ccccc1OCCCC(=O)N(C)C1(C#N)CCC1 +O=c1c2ccccc2ncn1CC(O)c1ccccc1 +CNc1cnn(-c2ccc(C(N)=O)cc2)c(=O)c1Cl +O=C1CN(Cc2cc(=O)n3ccsc3n2)c2ccccc2N1 +COc1cc(N2CCN(Cc3ccc4c(c3)OCO4)C(=O)C2)ncn1 +CCc1ccc(OC)c(S(=O)(=O)n2ccc(C)n2)c1 +COCc1nc2cc(Br)cnc2n1CCO +C=CCNC(=O)c1ccc(NC(=O)N2CCOC(C)C2)cc1 +NC(=O)c1ccc(-n2ccnc2-c2cccnc2)cc1 +CC(C)CNC(=O)Cn1ncc2c(N3CCCCCC3)ncnc21 +CC(C#N)CN(C)C(=O)Nc1cnn(CC(N)=O)c1 +CCC(C)C1NC(=O)C2CN(C(=O)c3cccc(C)c3)CCN2C1=O +COc1cccc(S(=O)(=O)Nc2ccc3c(c2)CCC(=O)N3C)c1 +Cc1ccc(C(=O)C(C#N)c2nnc3n2CCCCC3)s1 +C=CCN1CCC2(CN(c3ncc(CC)cn3)CC2C)C1=O +OCc1ccc(Cl)c(NCc2ccc(F)cc2F)c1 +NC(=O)NC1CCN(C(=O)Cc2ccc(OC(F)F)cc2)CC1 +COCCOC(=O)Cn1c(=O)c(C)nc2ccc(N)cc21 +N#CC(NCC(F)(F)F)c1ccc2c(c1)OCCCO2 +Cc1cc(C(=O)NCCS(=O)(=O)c2ccccc2)c(C)n1C(C)C +CS(=O)(=O)NCC(=O)NC1CCSc2ccc(Cl)cc21 +Cc1ccc(C(=O)Nc2ccc(NCC(C)O)nc2)cc1 +CCOC(=O)c1c(N)c(-c2ccccc2C)n(C)c1C +COc1cccc(CNC(=O)C(NC(C)=O)C(C)C)c1OC +CN(C(=O)OC(C)(C)C)C(C#N)c1ccc(O)cc1 +CC(NC(=O)NC1CCc2ccccc21)C(=O)NCc1ccccc1 +Cc1nnc(SCC(=O)Nc2ccc(C(C)C)cc2)s1 +CC(C)CNC(=O)C1CCN(c2ccc(F)c(Cl)c2)C1=O +COc1cccc(C(=O)Nc2ccc(CC#N)cc2)c1OC +Cc1nnc(-c2cccc(Cl)c2)nc1N1CCCC1 +CN1C(=O)CCC12CCN(C(=O)c1ccc[nH]1)CC2 +Cc1occc1C(=O)N1CCCC2(CCNC2=O)C1 +CCCc1c(C(F)(F)F)nn(-c2ccccn2)c1N +COc1ccc(COc2c(N)cccc2Cl)cc1OC +Cn1c(=O)c2c3c(sc2n2nnnc12)COC(C)(C)C3 +Cn1c(N)nnc1SCc1c(Cl)cccc1Cl +CC(NC(=O)CN1C(=O)c2ccccc2S1(=O)=O)c1ccccc1 +CC(C)(C)NC(=O)CNc1ccccc1C(F)(F)F +CCOc1ccc(-c2cc(C)nc3onc(N)c23)cc1 +CN(C)c1ncncc1N1CCC(C(=O)NC2CCCC2)CC1 +CCCc1cc(=O)[nH]c(SC(C)C(=O)NCC(F)(F)F)n1 +COc1cc2c(cc1CNC(=O)Nc1cnccc1C)OC(C)C2 +O=C(CC1CCCCC1)OCn1nnc2ccccc2c1=O +Cc1cc(S(=O)(=O)NCC(C)O)c(Cl)cc1Cl +CC(Nc1cnc2ccccc2n1)c1ccc2c(c1)NC(=O)CO2 +Cc1ccc(Cl)cc1Nc1ncnc2c1cnn2C +CC(Sc1nnc(-c2cccs2)n1N)C(=O)NC1CCCC1 +CCNc1ccnc(N2CCN(CC(=O)OC)C(=O)C2)n1 +Cc1ccccc1CNC(=O)CCC(=O)c1ccc2c(c1)OCCO2 +C=CCNC(=O)c1ccc(C)c(S(=O)(=O)N(CC)CC)c1 +O=C(CCO)N1CCc2[nH]nc(-c3cccc(F)c3)c2C1 +O=C(Cc1cccs1)NCC#Cc1ccc(N2CCOC2=O)cc1 +Cc1csc(N2CCN(CC(=O)N3CCCCC3)CC2)n1 +CCc1ccc(NC(=O)CCNC(=O)c2ccc(OC)cc2)cc1 +O=C(CCc1ccccc1)N1CCN(c2ncccc2F)CC1 +CCCNC(=O)c1cc2cnn(C3CCCCC3)c2nc1N +Cc1cc(C)n(-c2ccc(CCNC(=O)NCc3ccon3)cc2)n1 +Cc1cnn(-c2ccc(C(=O)N(C(C)C)C3CCOCC3)cc2)c1 +CC(C)NC(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +CC(C)(C)C(=O)N1CCN(C(=O)Nc2ccc(F)cc2C#N)CC1 +Cn1nc(-c2cc(N)nc3[nH]ccc23)nc1N1CCCCC1 +CN(C)C(=O)CN(CC(F)(F)F)C(=O)c1cccs1 +Cc1oc(C2CC2)c(-c2nnc(NC(C)C)s2)c1C +CCSc1ccc(NC(=O)NCCNC(=O)c2ccco2)cn1 +CN(C)C(=O)CN(c1ccc(F)cc1)S(=O)(=O)c1ccccc1 +O=C(NCc1ccccn1)c1ccc(S(=O)(=O)N2CCCC2)o1 +COc1ccccc1C(C#N)NC(=O)c1ccc(F)c(F)c1 +COCCNC(=O)NCc1nc2ccccc2c(=O)n1C +COC(CNS(=O)(=O)c1ccc(C)cc1)c1ccc(C)s1 +O=C1CCC(C(=O)N(CCO)Cc2ccc(Cl)c(Cl)c2)N1 +CC(=O)Nc1cccc(C(=O)OCC(=O)Nc2ccc(C)c(C)c2)c1 +CCOc1ncccc1C(=O)N(C)Cc1ccc(C(=O)OC)cc1 +CCN1CC(C)N(C(=O)c2n[nH]c3ccccc23)CC1C +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)NCc1ccccc1 +CCC(NC(=O)Nc1ccc2nccnc2c1)C(C)C +COc1ccc(S(=O)(=O)N2CCN(c3ncccn3)CC2)cc1C +N#Cc1ccc(COc2ccc3ncccc3c2)cc1 +CC1CCCC(C)N1C(=O)c1cc(-c2ccco2)on1 +CN(C)c1ncc2c(n1)C1(CCN(S(=O)(=O)C3CC3)C1)COC2 +Cc1ccccc1C(=O)NCC(=O)N1CCC(C)CC1 +CCOc1ccc2c(=O)ccn(CC(=O)OC)c2c1 +COc1cc(C)sc1C(=O)NC(C)c1nc(C)no1 +COc1ncnc2c1Nc1ncnc(OC)c1S2 +CN(Cc1nc2ccccc2s1)C(=O)CNC(N)=O +CC(c1ccc(S(C)(=O)=O)cc1)N(C)CCCN1CCOCC1 +Cc1cc(CCNC(=O)OC(C)(C)C)ccc1O +COCc1cc(C(=O)N2CCCCC2c2nccs2)ccc1F +CC(C)(C)OC(=O)C1CCCN1S(=O)(=O)N1CCOCC1 +Cc1cc(NC(=O)N(C)C(C)c2ccncc2)ccc1C(=O)N(C)C +CCc1ccc(S(=O)(=O)Nc2ccccn2)cc1 +Cn1nc(C(=O)N2CCC3(CC2)CNC(=O)C3)cc1-c1ccccc1 +COc1ccc(CC(C#N)C(=O)N(C)c2ccccc2)cc1 +O=C(Cc1ccccn1)c1csc2ccccc12 +COC(=O)N1CCC(NC(=O)Nc2cccc(C)c2C)CC1 +CC(=O)C(NC(=O)CN1CCCc2cc(Cl)ccc21)C(C)C +N#CC1(c2ncnn2C2Cc3ccccc3C2)CCOCC1 +COCCNC(=O)COC(=O)c1cc(N)c(C)s1 +Cc1noc(C)c1COc1ccc(C(=O)OCCO)cc1 +Cc1csc(N2CCN(C(=O)Cc3ccc[nH]3)CC2)n1 +COc1ccccc1C(NC(=O)c1cc(C)n[nH]1)c1ccccn1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1ccc(-n2cncn2)cc1 +Cc1ccc(CC(=O)NCc2nnc3nc(C)cc(C)n23)cc1 +CC(c1nc(C2CC2)no1)N1CCN2C(=O)NCC2C1 +CC1CN(c2nn3c(=O)cc(-c4ccccc4)nc3s2)CCO1 +COCCCC(=O)Nc1sc2c(c1C#N)-c1ccccc1CC2 +O=S(=O)(NCCO)c1cccc(Br)c1 +CC(=O)NC(CC(=O)N1CC(C)OC(C)C1)c1cccs1 +CC(Sc1nnnn1C1CC1)C(=O)Nc1ccc(Cl)cc1 +COc1ncccc1C(=O)NCc1cccc(NC(C)C)c1 +O=C(NCCOc1cccnc1)NCC(O)c1ccccc1Cl +COc1ccccc1-c1cc(C(=O)N2CCC(C)CC2)[nH]n1 +Cc1cccc(C(O)CNC(=O)Cc2cccc(OCC#N)c2)c1 +Cn1cc(CNC(=O)Cn2nnc(-c3ccc(Cl)cc3)n2)cn1 +Cc1cc(Nc2ccc(Br)cc2)n2cnnc2n1 +O=C(NCCOc1cccnc1)c1ccc(-n2cccc2)c(F)c1 +Cc1noc(C)c1COc1ccccc1C(=O)NCC1CCOC1 +COc1cccc(-c2nn3c(-c4cc(C)n[nH]4)nnc3s2)c1OC +NC(=O)NCc1ccc(C(=O)N2CCN(c3ccccc3)CC2)cc1 +Cc1cccc(Cl)c1NC(=O)NC1C=CC(CO)C1 +O=C(NCc1cc2ccccn2n1)c1ccc2c(c1)OCO2 +c1cc(C2NCCc3cc4c(cc32)OCCO4)cnn1 +CCOC(=O)c1[nH]nc(-c2ccc(OCC)cc2)c1N +COc1cccc(NC(=O)CCC(=O)c2cc(C)sc2C)c1 +CCC1CN(CC(=O)NC2CCCC2)c2c(N)cccc2O1 +CC(C)C(=O)N1CCCC1C(=O)NCCNC(=O)c1cccnc1 +CCOC(=O)C=C(C)NC(=O)c1ccccc1Br +CC(=O)NC1CN(c2cccc(C#N)n2)CC1c1ccc(C)cc1 +Cc1ccc(-c2nc(CNS(=O)(=O)N(C)C)co2)cc1 +CN(CCO)c1ncc(Br)c2ccc(Cl)cc12 +Cn1ncc(NC2CC=CCC2)c(Br)c1=O +CCOC(=O)c1c(C)[nH]c(C(=O)N2CCCC2c2ccccc2)c1C +Cc1ccc(C(=O)N2CCOCC2c2ncon2)cc1C +CNC(=O)c1cc(OC2CC2)cnc1OC(C)C +CCCCc1cc(C(=O)Nc2ccc3c(c2)CCN3C(C)=O)[nH]n1 +Fc1cc(Cl)ccc1-c1nnc2sc(C3CCC3)nn12 +Cc1cc(C(F)F)n2ncc(C(=O)NCc3ccncc3)c2n1 +Cc1ccccc1CNC(=O)C(C)S(=O)(=O)c1ccccc1C +COCCN1CC(C(=O)NCc2ccnn2C)CC1=O +Cc1cccc2c1ccn2CCC(=O)N1CCNC(=O)C1 +COC(=O)c1cc(C2CC2)nc2c(Br)c(C)nn12 +Cc1cc2nc(-c3ccccc3)cc(NCCC(=O)N3CCCC3)n2n1 +Fc1ccc(CSc2nnnn2C2CCCC2)cc1F +Cc1csc(=O)n1CC(=O)NCC1CCCC(C)C1 +C=C(C)Cn1c(SC)nc2c1c(=O)[nH]c(=O)n2C +Cc1ccc(C)n1-c1c(C(=O)N(C)C)sc2ncccc12 +CC(=O)c1cccc(OC(=O)C2CC(=O)N(c3ccc(C)cc3)C2)c1 +CCCC1=C(C(=O)OC)C(c2ccc(O)c(OC)c2)NC(=O)N1C +O=c1cc(C2NCCc3ccc4cc[nH]c4c32)cc[nH]1 +Cc1ccc(NC(=O)COC2CCCCC2)cc1S(C)(=O)=O +Cc1noc(-c2ccc(N(C)Cc3nnc(-c4ccccc4)o3)nc2)n1 +CC(=O)c1csc(NC(=O)c2nc(-c3cccs3)oc2C)n1 +Cn1cc(CNC(=O)C2(c3ccc(F)cc3)CC2)cn1 +CCOC(=O)N1CCN(CC(O)COc2ccc(F)cc2)CC1 +NC(=O)c1cc2c([nH]c1=O)CCCC2NC(=O)c1ccc(Cl)cc1 +CCNC(=O)c1cn(C(C)C)c2cccc(N)c2c1=O +CCC(C(=O)N1CCOC2CCCCC21)c1c(C)noc1C +CN(C)C(=O)CCNS(=O)(=O)c1ccc(Cl)c(C#N)c1 +Cc1nc2ccccc2n1CC(O)COc1ccc(CC#N)cc1 +Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCCCC3)c(C)n1 +Cc1c(C(=O)Nc2ccccc2)cnc2ncnn12 +Cc1ccc(NCc2nc3n(n2)CCCCC3)cc1Cl +CN1CCN(C(=O)c2cccc(Cl)c2)C(c2ccccc2)C1 +COC(=O)c1ccc2c(c1)CCN2C(=O)c1cccc(OC)c1F +Cc1cc(C(=O)CCC(=O)N2CC(C)OC(C)C2)c(C)s1 +CCOCCNS(=O)(=O)c1cnn(-c2ccccc2)c1 +CCOC(=O)c1[nH]c(C)c(S(=O)(=O)NCc2ccccn2)c1C +Cc1[nH]nc(CCC(=O)NCC2CN(S(C)(=O)=O)CCO2)c1C +CCNC(=O)C1CCN(Cc2nc3c(F)cccc3[nH]2)CC1 +CCOc1ccc(CN(C)C(=O)c2cc3ccccc3o2)cc1OC +COCCNc1ncnc(Oc2ccccc2OC)c1N +CCC(C#N)(C#N)C(Cc1cncn1C)C(=O)OC +CC(C)(C)CCC(=O)Nc1cccc(Cn2cccn2)c1 +C=CCN(C(=O)COC1CCCC1)c1ccccc1 +COc1ccc(F)c(NC(=O)CCC(=O)c2ccc(F)c(F)c2)c1 +Nc1ccc(C(=O)NCC2(c3ccccc3)CCCC2)cc1 +CCOCCCn1c(=NC(=O)C2CCC(=O)N2)[nH]c2ccccc21 +COc1ccccc1C(C)NC(=O)C(C)N1CCOC(C)(C)C1 +O=C(Nc1ccnn1Cc1ccco1)c1cc(=O)c2ccccc2o1 +CCN1C(=O)CCc2cc(NC(=O)Nc3ccc(C)cc3)ccc21 +COCC(=O)NCc1cccc(S(N)(=O)=O)c1 +Nc1cc(NC(=O)CCCOCC2CC2)ccc1Cl +CCC(C)Nc1nnc(-c2ccc(C)[nH]c2=O)s1 +CCc1cnc(CN(C)C(=O)c2c(O)cnc3ccccc23)s1 +CC(O)CN1CCN(C(=O)Cc2ccc(F)cc2)CC1 +CC(=O)c1ccccc1NS(=O)(=O)c1cccs1 +O=C(NCCc1ccccn1)Nc1ccc(Oc2ncccn2)cc1 +COc1ccccc1CC(=O)NCCc1nc2ccccc2s1 +COc1ccccc1C(C)NC(=O)C1CCc2[nH]ncc2C1 +COc1ccnc(NC(=O)COCc2nc(C)no2)c1 +CC(=O)Oc1ccc2occ(C(=O)c3ccccc3)c2c1 +CCn1cc(N)cc1C(=O)N1CCC(C(N)=O)CC1 +COC(=O)NCC(=O)Nc1ccc2c(c1)oc(=O)n2C +OC(c1cccs1)C1CCN(c2nnc(C3CCC3)o2)CC1 +N#Cc1cccc(Cn2cnc3cc(Cl)cnc32)c1 +CC(=O)Nc1ccc(CCNC(=O)N(C)C(C)C)cc1 +CC(=O)Nc1cccc(CNC(=O)CCNc2cc(C)cc(C)c2)c1 +CC(C)CC(C#N)NC(=O)COC1CCCCC1 +COc1ccc(OC)c(Nc2cc(C#N)ccn2)c1 +COc1cccc(OCCc2ncc(CC#N)s2)c1 +Cc1ccccc1NC(=O)NC(C)Cc1ccco1 +CC(C)c1ccccc1NCC(O)c1ccc(F)c(N)c1 +C=CCNc1ncc(C(=O)N2CCOC(CCC)C2)s1 +CC(NC(=O)C1CCCCN1C(=O)c1ccccc1)c1ccncc1 +COCCNC(=O)c1nn(C)c2ccccc2c1=O +Cc1noc(C2CCN(C(=O)Cc3cccs3)CC2)n1 +CC(NC(=O)c1n[nH]c2ccccc12)c1ccncc1 +Fc1ccc(CSc2nncn2C2CC2)cc1Br +CCc1ccccc1NC(=O)NCCc1n[nH]c(=O)[nH]1 +CC(C)N(C(=O)c1ccc(OCC(F)F)nc1)C1CCCC1 +COc1ccc(NC(=O)c2ccc(OCC(F)F)nc2)c(C)n1 +CCOc1ccc(NC(=O)c2cc(-c3cccs3)[nH]n2)cc1 +Nc1nc(C2CC2)ncc1C(=O)NCc1ccncc1 +CC(=O)N1CCN(C(=O)Nc2ccccc2)CC2(CC(=O)N(C)C2)C1 +CSc1ccc(CC(=O)N2CCC(=O)CC2)cc1 +c1ccc(CNc2c3c(nc4ncnn24)CCC3)nc1 +CCN1C(=O)CCc2cc(NS(=O)(=O)c3cccs3)ccc21 +Cc1cc(C(=O)N2CCN(c3ccccc3C)C(=O)C2)nc(C)n1 +COC(=O)C(C)(C)NC(=O)c1cnn(Cc2ccccc2)c1C +Cc1cccc(C)c1OCCC(=O)N(C)C1(C#N)CCC1 +COc1ccc2c(c1)CN(C(=O)c1ccc[nH]1)CC2 +CC1CN(Cc2nc(CC(=O)NCc3ccccc3)no2)CC(C)O1 +CCN(CCO)C(=O)COc1c(C)cccc1C +COCCOCC(=O)N1CCCC1Cc1ccc(C)cc1 +CC(C)N(CC(=O)OC(C)(C)C)Cc1cccs1 +Cc1cc2cc(CN3CCC4(C3)OCCO4)oc2cc1C +Cc1sc2nc(CO)cn2c1-c1ccc(Cl)cc1 +COc1ccc(CN(C(=O)Cn2ccnc2)C2CC2)cc1 +CCC(=O)Nc1nnc(SCc2ccccc2)s1 +Cn1cnc(CNC(=O)c2cc(Cc3ccccc3)ccc2O)n1 +Cc1ccc(CC(=O)Nc2cc(Cl)ccc2C(N)=O)s1 +COc1ccccc1CCNC(=O)C1CCCCN1S(C)(=O)=O +N#CC1(C(=O)Nc2ccc(F)c(Cl)c2)CCCC1 +Cc1nn(C)c(=O)c(C(=O)N(C)CCOCC2CC2)c1C +CSc1ncccc1C(=O)OCC(=O)NC1CC1 +COc1ccccc1NC(=O)C(C)NC(=O)C1CCCCC1 +Cc1ccc(CNC(=O)CN(C)c2ccc(Cl)cn2)s1 +NS(=O)(=O)c1ccc(NCc2ccc(Cl)cc2)cc1 +Cc1ccsc1CNC(=O)N1CC2CCC1C2 +COC(=O)NCCOC(=O)c1csc(-c2ccccc2Cl)n1 +CCOC(=O)CN(C)C(=O)c1cc(Cl)ccc1F +CNS(=O)(=O)c1ccc(C(=O)NCCCn2cncn2)o1 +Cc1ccc(N2CC3(CCN(C(=O)c4cnccn4)C3)CC2=O)cc1 +CCNc1nc2ccc(S(N)(=O)=O)cc2s1 +CN(Cc1n[nH]c(=O)[nH]1)c1ncccc1C(F)(F)F +CCC(CC)c1cc(CNC(=O)c2ccc(-n3ccnc3)nc2)on1 +COC(=O)COc1ccc(NC(=O)Cc2cccc(F)c2F)c(C)c1 +Cc1ccc(N)c2c(Br)cnc(N(C)C)c12 +CCCn1nccc1NC(=O)C(C)OCC1CC1 +CCCC1CCN(C(=O)c2ccc(N)cc2N)CC1 +CC(C)Cc1nc2n(n1)C(C(=O)Nc1ccc(F)cc1)CC(=O)N2 +N#CC(NC(=O)c1cccc(-n2cccn2)n1)c1ccccc1F +Cc1csc(-c2cccc(OCC(=O)NCC3CCOC3)c2)n1 +Cc1cc(C)n(CC(C)NC(=O)C2(c3ccccc3F)CC2)n1 +CC1CCCC(C)N1C(=O)CNc1ccccc1F +COc1ccc(CC(=O)NCCc2cc(C)no2)cc1OC +N#CC(NC(=O)Cc1ccc[nH]1)c1ccccc1F +CCC(NS(=O)(=O)c1ccccc1)c1nc(-c2ccccc2)c[nH]1 +Cc1ccc(C(=O)Nc2cc(N)ccc2C)cc1C +Cc1csc(N(C(=O)Cc2c(F)cccc2F)C2CC2)n1 +O=C(CCNC(=O)c1ccccc1Cl)Nc1ccncc1 +COc1ccc(C2CC(=O)N(c3ccc(C)cc3)C3=C2C(=O)OC3)cc1 +COc1ccc(C(C#N)C(=O)c2cc(OC)c3c(c2)OCO3)cc1 +CCC(NC(=O)NC(C)c1ccccn1)c1cccs1 +O=C1NCC2(CCCN(C(=O)c3ccc4c(c3)CCO4)C2)O1 +CCCn1cc(NC(=O)NC2CCCC2C(=O)OC)cn1 +CC(NC(=O)c1ccc(OC(C)c2ccccc2)nc1)c1ccncc1 +Cc1nc(C)c(CCC(=O)NCCN(C)c2ccccc2)c(=O)[nH]1 +Nc1ccccc1CC(=O)NCCc1cccs1 +Cc1cc(NC(=O)c2cccc(NC(=O)c3ccco3)c2)ccn1 +CC(C)CCNC(=O)C1(c2cc(-c3ccco3)on2)CC1 +NC(=O)CCCNC(=O)C1(c2ccc(Cl)cc2)CCOCC1 +COc1cc(C(=O)N2CCc3[nH]ncc3C2)nc(OC)n1 +CC(=O)N1CCC(NC(=O)NC2CCC(O)CC2)CC1 +COc1ccc(C(=O)N2CCCC(C(=O)N3CCCCCC3)C2)cc1 +CC(C)(C)C1CCC(OC(=O)C2CCCN(C(N)=O)C2)CC1 +COc1ccc(C2NCCN(C)C2=O)c(Cl)c1Cl +O=C(CCCc1c[nH]c2ccccc12)Nc1cccc(-n2cnnn2)c1 +Cc1nn(COc2ccc(Cl)c(Cl)c2)c(C)c1N +COC(=O)c1cc2cc(F)c(F)cc2cc1Cl +Cc1noc(C)c1N(C)S(=O)(=O)c1cc(Cl)cc2c1OCC2 +Cc1ccc(-n2nc(C(=O)NCC(N)=O)c3c2CCC3)c(C)c1 +Cc1ccc(-c2nnc(SCC(=O)C(C)(C)C)n2N)cc1 +CC(NC(=O)CCC(=O)c1cccs1)c1ccccc1F +CCCC(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O +COc1ccc(C(=O)Nc2c(C#N)cnn2-c2nc(C)cc(C)n2)cc1 +CC1CCc2c(C(=O)Nc3ccc4c(c3)OCC(=O)N4)csc2C1 +COc1ccc(NC(=O)C2(C)CC2(Cl)Cl)cn1 +CCNC(=O)N1CCCN(C(=O)c2ccccn2)CC1 +COC(=O)C1CN(C(=O)C2CC2)CCN1C(=O)c1ccccc1 +N#Cc1ccccc1COc1cccc(NC(=O)c2ccco2)c1 +CCc1noc(CN(C)C(=O)CCCc2cc(F)ccc2F)n1 +Cc1ccc(CNC(=O)C2CC(O)CN2C(=O)OC(C)(C)C)cc1 +COc1cccc(-c2n[nH]c(-c3cnccn3)n2)c1 +Cc1ccc(C)c(NC(=O)C(C)Sc2ccc(N)nc2)c1 +CCC(C)c1cc(C(=O)N2CCC(O)(C(F)(F)F)CC2)on1 +COc1ccc(NC(=O)N2CCN(C(=O)C3CC3)CC2)cc1Cl +Cc1nn(CC(=O)NCc2nc3ccccc3[nH]2)c(C)c1Cl +CCNC(=O)c1ccc(CNC(=O)Nc2ccc(Cl)c(F)c2)cc1 +C=CCN1CCC2(CCN(c3ccc(C)nn3)CC2)C1=O +CCN(CC(=O)NC(C)C)C(=O)c1ccc2c(c1)OCCO2 +CC1CN(CCCNC(=O)Nc2ccccn2)CC(C)O1 +CNC(=O)COC(=O)c1cc(-c2cccs2)nc2ccccc12 +CCCC(C(=O)OC)c1cc(OC)ccc1OC +CCOc1cc(C(=O)Nc2cc(C)cc3cccnc23)ccc1OC +O=C1CC(C(=O)NCc2ccc(C(F)(F)F)cc2)c2ccccc2N1 +O=C(c1c[nH]c2ncccc12)N1CCN(c2ccccc2)CC1 +CCc1ccc(C(C)NC(=O)c2c(C)nn3c(C)cc(C)nc23)cc1 +COC(=O)c1ccc(S(=O)(=O)Oc2ccccc2F)cc1 +Cc1ccc2c(c1)CCN2CCc1ccc(C)nc1 +COc1ccc(C(=O)N2CCCCCC2c2cccn2C)cc1 +Cn1cc(CNC(=O)c2csc(-c3ccsc3)n2)cn1 +CC#CC1NCCc2ccc(O)c(C(F)(F)F)c21 +Cc1ccc(-n2c3c(cc(C#N)c2=O)C(=O)CCC3)cc1 +Cc1cc(C)cc(C(=O)N2CCC(Oc3cccnn3)CC2)c1 +O=S(=O)(Nc1ccccc1CO)c1ccc2c(c1)OCCO2 +NC(=O)CSc1nc(-c2ccccc2)c(NC(=O)C2CC2)s1 +CC(NC(N)=O)C(=O)Nc1ccc(F)c(C(F)(F)F)c1 +Cc1ccc(NC(=O)c2cc(CN3CCOCC3)on2)c(C)c1 +C=CCn1c(CC)nnc1SCc1ccc(OC)cc1 +COc1ccccc1CCNC(=O)C1CC=CCC1 +Cc1ccc(OCC2CCCN(C(=O)CCc3nncn3C)C2)cc1 +CCOc1ccccc1NC(=O)NCc1nc(C)no1 +NC(=O)c1cccnc1N1CCN(c2ccccc2)CC1 +Cc1ccccc1CN1CCN(c2ccc(O)cc2)CC1 +CCc1nn(C)c(CC)c1CNC(=O)Nc1c(C)noc1CC +CC(CNC(=O)NCC(C)c1ccsc1)CC1(C)OCCO1 +COc1ccccc1C(NC(=O)NCc1noc(C)n1)C(C)(C)C +Cc1noc(CCC(=O)NCC2CCC(C)(C)CC2)n1 +Cc1cncc(C2CCN(C(=O)c3cnccn3)CC2)n1 +CC1(CNC(=O)NC2CCCN(Cc3ccccc3)C2=O)CCC1 +N#Cc1cc(F)ccc1CN1CCOCC1C(N)=O +CSc1ccc(CNC(=O)NCC2CN3CCCC3CO2)cc1 +COc1ccc(CN(C)c2ncnc3c2cnn3-c2ccccn2)cc1 +COc1ccc(NC(=O)CSc2ccccc2O)cc1 +Cc1cncc(NCc2cnc(N3CCOCC3)nc2)c1 +CCCn1c(C2CCN(C(=O)CC3CCCC3)C2)nc2cccnc21 +COCCCN1CC(C)(c2ccccc2)CCC1=O +CCN(C(=O)c1c[nH]c2cccc(F)c12)c1nc(C)cs1 +CNC(=O)c1c(-c2cccc3ccccc23)cnnc1N +CC1CCCN(S(=O)(=O)NCCc2nc(C(C)C)no2)C1 +CN(Cc1ccc(F)cc1)C(=O)CCc1nc2ccccc2s1 +CC(=O)N1CCN(C(=O)Cn2nc(C)c(Cl)c2C)CC1 +CC(CCc1ccccc1)NC(=O)c1cnn(C)c1-n1cccc1 +CCCn1cc(NC2CCN(C(=O)CC(C)(C)C)CC2)cn1 +COC(=O)c1[nH]c2cc(OC)c(OC)cc2c1NC(C)=O +CN(CCC#N)C(=O)CCCNC(=O)c1ccco1 +CC(C(=O)N1CCCCC1)S(=O)(=O)c1ccc2ccccc2c1 +CC(=O)Nc1sc2c(c1C(=O)Nc1ccc(C)cc1)CCCC2 +Cc1c(C(=O)NCc2cccnc2)oc2c1C(=O)CC(C)(C)C2 +CN(CCC#N)C(=O)CSc1ccc(F)c(Cl)c1 +Nc1ccccc1-c1nn2c(=O)c3ccccc3nc2n(N)c1=O +CCCCCC(=O)NCc1ccc2c(c1)OCCO2 +Cn1ccnc(Sc2nc(-c3ccccc3)cs2)c1=O +O=C(NCc1cn2ccsc2n1)NCc1csc2ccccc12 +O=C(NCCCOCC1CCOCC1)Nc1ccc(Cl)c(F)c1 +CC1CN(C(C)(C)CNC(=O)CCCc2cccs2)CC(C)O1 +CC1Cc2ccccc2C1NC(=O)Nc1ccc2c(c1)COC2 +NC(=O)Cc1ccc(NC(=O)CCC(=O)c2ccc(F)cc2F)cc1 +CCCn1c(SCC(=O)Nc2nccs2)n[nH]c1=O +Oc1ccc2c(c1)NCC(Cc1ccccc1F)O2 +Cc1ccc(NC(=O)NC(C)CO)cc1NC(=O)NC(C)CO +O=C(NCc1cc(Br)c2c(c1)OCO2)NCC1CCC1 +C=CCc1ccccc1OCC#CCNC(=O)Cn1cccn1 +CCOc1cccc(CNC(=O)N2CC(C)OC(C)C2)c1 +CC(C)NC(=O)N1CCCN(S(=O)(=O)C(C)C)CC1 +COc1ccc(-c2cc(C(=O)NCc3cccs3)n[nH]2)cc1 +COc1ccc(CNc2cnccc2Cl)cc1O +COc1ccc(O)c2c1C(c1ccc(=O)[nH]n1)NCC2 +CN(Cc1ccccc1OC(F)(F)F)C(=O)c1cscn1 +COC(=O)CC(NC(=O)c1ccccc1F)c1ccc(OC)cc1 +CCc1nn2c(CO)c(-c3ccncc3)nc2s1 +COC(=O)CN1CCC(N(C)C(=O)OC(C)(C)C)CC1 +O=C(CC1CCCC1)NCCC(O)c1ccoc1 +CC(C)(C)OC(=O)Nc1ccc(-c2ccncc2)c2c1CNCC2 +c1cncc(CN2CCN(Cc3cnc4cnccn34)CC2)c1 +CS(=O)(=O)NCC(O)c1ccc(F)c(F)c1 +Cc1csc(S(=O)(=O)CC(=O)NC(C)c2ccc(F)cc2)n1 +CC(Sc1nnc(C2CC2)o1)C(=O)NCc1ccc2c(c1)OCO2 +CSc1ccc(C)c(C(=O)NCCNC(=O)c2ccc(F)cc2)c1 +COc1ccc(C)cc1S(=O)(=O)n1cnc(C)c1 +Cc1nc(-c2ccc(OCc3nnc(C)o3)cc2)no1 +COc1cccc(C(=O)OCc2nc(N)c3ccccc3n2)c1O +O=C(NCCC(O)C(F)(F)F)NC1CCc2ccc(F)cc21 +CCOC(=O)c1ccc2c(c1)nc1[nH]c(NC3CC3)nn12 +O=C(Cc1ccccc1O)NCCc1ccccc1 +O=C(NCc1cccc(Cl)c1)c1cccc2ccoc12 +O=C(c1ccsc1)N1CCC2OCCCC2(COCC2CC2)C1 +CC(=O)Nc1ccc2nc(NC(=O)CN3CCOCC3)sc2c1 +O=C(Cn1ccccc1=O)Nc1ccc(N2CCOCC2)nc1 +CC1CN(Cc2cccc(S(=O)(=O)N(C)C)c2)CC(C)O1 +Cc1ccc(Cn2cc(Br)c(NS(C)(=O)=O)n2)cc1 +O=C(Nc1ccccc1)Nc1nccn(-c2cccc(Cl)c2)c1=O +Cc1cc(NC(=O)c2cc(C3CC3)nc3onc(C)c23)on1 +COc1ccccc1NCC(=O)N1CCN(c2ccccc2F)CC1 +Cn1c(SCc2cccs2)nnc(-c2ccccc2)c1=O +COc1cc(C)ccc1OCC(=O)NCCc1ccccc1F +COc1ccc(CCNC(=O)C2(C#N)CC2)cc1OC +COc1cc(CC(=O)NCc2ccc(C)s2)cc(OC)c1OC +CN(CC(=O)N(C)C1(C#N)CCC1)C(=O)c1cccs1 +CC(C)(C(=O)NCC(=O)N1CCCC1)c1cccc(C(F)(F)F)c1 +O=C(Cn1nnc2ccccc2c1=O)c1ccc2c(c1)OCCO2 +Cc1ccc(C)c(OCC(=O)Nc2ncccc2C)c1 +Cc1ccc(C(=O)Nc2ccc(-n3ccnc3C)nc2)c(=O)[nH]1 +CC(C)(CNC(=O)C(C)(C)c1cccc(C(F)(F)F)c1)C(N)=O +O=C(Nc1ccc2[nH]ncc2c1)c1ccc(Cl)c2cccnc12 +CCNc1nc(NCc2cccc(Cl)c2)c2cnn(C)c2n1 +O=S(=O)(c1cccs1)N1CCC(c2nnc3ccccn23)CC1 +CC(C)(C)NC(=O)c1ccc(N)c(Br)c1 +O=C(COc1ccc2c(c1)CCC(=O)N2)Nc1cc(F)ccc1Cl +COc1ccc(OC)c(C(=O)COC(=O)c2ccsc2)c1 +CC(C)CCCC1CN(C(=O)CN2CCCC2=O)CCO1 +O=C(CCCNC(=O)c1ccnc2c1OCO2)Nc1ccccc1 +CC(=O)Nc1cc(Cl)ccc1NC(=O)c1scnc1C1CC1 +CCC(=O)Nc1ccc(C(C)NS(=O)(=O)CC)cc1 +c1coc(C(CNCc2cccs2)N2CCCC2)c1 +O=C(CCn1cnnn1)NCc1cc(-c2cccc(Cl)c2)no1 +Cc1nccn1-c1ccc(C(C)Nc2cnn(C)c(=O)c2Cl)cc1 +CC(C)c1cc(C(=O)NC2CCc3c(F)cccc32)n[nH]1 +COc1ccccc1NS(=O)(=O)c1ccc(F)c(F)c1F +CCOC(=O)c1ccc(-n2nc(C)c3c(C)cc(=O)oc32)cc1 +O=C(Nc1ccc(F)cc1F)N1CCN(Cc2ccc(F)cc2)CC1 +Cc1c(NCc2cc(C(F)(F)F)n(C)n2)cnn1C +CCCCCNC(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +CCC(CO)NS(=O)(=O)c1c(Cl)cccc1Cl +COC(=O)c1ccccc1Sc1nc2sccn2c1C#N +Cc1cc(N2CCN(c3ccc(C#N)cc3F)CC2)n2ncnc2n1 +O=C(NCc1ccc(-n2cccn2)cc1)C1Cc2ccccc21 +Cc1ccc(CCC(=O)Nc2ccc(S(N)(=O)=O)c(C)c2)cc1 +CCc1cc2c(NC3CCN(C(=O)C(C)C)CC3)ncnc2s1 +CC(=O)NCCC(=O)Nc1nc2c(C)ccc(C)c2s1 +CCc1ccc(C(=O)NCc2nc(C)cc(N(C)C)n2)cc1 +COCCN1CCc2ccc(=O)n(Cc3cccnc3)c2CC1 +Cc1ncc(C(=O)N2CCC(C(O)CC(C)C)CC2)cn1 +CC(=O)Nc1ccc(O)c(C(=O)NC2CCC(C(F)(F)F)CC2)c1 +CCC(=O)N1CCN(c2cc(Cl)c(C#N)cc2F)CC1 +COc1cccc(CC(=O)NCc2nncn2C(C)C)c1 +COc1ccc(NC(=O)C2=C(C)Nc3nc(SC)nn3C2)cc1 +Cc1ccsc1CN1CC2COCC2(COCc2ccccn2)C1 +COc1cccc(NC(=O)CSc2nc3c(c(=O)[nH]2)CCCC3)c1 +O=c1c2cnc3nc(-c4cccnc4)nn3c2ccn1CCO +COc1ccccc1C=CC=c1sc2ncnn2c1=O +O=C(NCCNC(=O)c1cccnc1)c1ccc(Br)cc1 +CNS(=O)(=O)c1cccc(CNC(=O)NCc2ccco2)c1 +COc1ccc(Cn2cnc3sc(C)c(C)c3c2=O)cc1 +CCOc1ccc2cc(S(=O)(=O)N3CCOCC3)ccc2c1 +Cc1cc(S(=O)(=O)NCC2(O)CCOCC2)ccc1F +Cc1nc(CSc2cn[nH]n2)nc2ccccc12 +CCOCC(=O)N(C)C(C)c1cc2ccccc2o1 +O=C(NCC#CCN1CCOCC1)c1cc(-c2ccc(F)cc2)n[nH]1 +COc1ncccc1C(=O)N(Cc1cccc(C)c1)C1CC1 +N#Cc1ccccc1C1NCCc2cc(O)ccc21 +COc1cc(CN(C)Cc2nccs2)c(Br)cc1O +CC(NC(=O)c1ccc(C(N)=O)cc1)c1cccc(OC(F)F)c1 +CCn1ncc(Br)c1C(=O)Nc1cc(C)on1 +O=C(Nc1ccon1)c1cccc(S(=O)(=O)N2CCCCCC2)c1 +O=C(Oc1ccc(N2CCCC2=O)cc1)c1ccc(F)c(F)c1 +O=C1CCCN1CCCNC(=O)C1(c2ccc(F)cc2)CCCC1 +CN(CCO)C(=O)c1ccc2c(c1)N(C)C(=O)CC(C)(C)O2 +Cc1ccc(NC(=O)Nc2cccc(N)c2C)cc1 +Cc1c(C(=O)Nc2ccccn2)cnn1-c1ccccc1F +COc1ccccc1CCNC(=O)Cc1ccc(O)cc1 +COc1cc(C)ccc1OCC(=O)c1c[nH]c2ccccc12 +COCC(=O)N1CCC2(CC1)Nc1cc(OC)ccc1-n1cccc12 +COCC(NC(=O)COc1c(C)ccc(C)c1C)c1ccnn1C +CC1Cc2ccccc2N1c1ccc(S(=O)(=O)N(C)C)cn1 +O=C(Cc1ccc[nH]1)N1CCC(c2nc(-c3ccccn3)no2)CC1 +Cc1n[nH]c(SCc2c(F)cccc2Cl)nc1=O +CC(Cc1ccccc1Br)NCc1cc[nH]n1 +CC(=O)NC1CC2CCCC(C1)N2C(=O)Nc1ccc(F)cc1 +Cc1cccc(C(=O)N2CC3(COC(C)(C)OC3)C2)c1 +COCCN(C(C)COC)C1CC(C)CCC1C#N +O=C1CC(c2ccccc2Cl)=Nc2ccccc2N1 +CCc1cc(CNC(=O)C2CN(Cc3ccccc3)CCO2)[nH]n1 +COc1cccc(C(=O)NCC(=O)NCc2cnn(C)c2C)c1 +O=C(Nc1ccc(-n2cncn2)nc1)C1CC=CCC1 +CC(NC(=O)N1CCCN(C(=O)C2CC2)CC1)c1ccco1 +CC(=O)Nc1cccc(NS(=O)(=O)c2ccc3ccccc3c2)c1 +COCC(=O)N(C)CCOc1cccc(Cl)c1 +COCc1cccc(CNC(C)C(=O)N2CCOCC2)c1 +CN(C)c1ccc(-c2nn3c(-c4ccccn4)nnc3s2)cc1 +COC(=O)C1CCCCCC1NC(=O)Cn1nnnc1C(C)C +N#Cc1ccccc1N1CCCN(C(=O)C2CC2c2ccccc2)CC1 +CCCC(=O)c1ccc(N2CCOCC2)c(F)c1 +COC(=O)C1CCCN1C(=O)c1cc(-c2ccccc2)cs1 +N#CC(CC(=O)NC1CCCCC1)c1ccncc1 +CCn1c(SC(C)c2cccnc2)nc2sc(C)c(C)c2c1=O +CCOC(=O)CCc1c(N)n(C)c(=O)n(C)c1=O +COc1cccc(C(=O)Nc2ccccc2SC)c1 +CCCOc1ccc(CNC(=O)CN2CCOC(C)(C)C2)cc1 +CCNc1nc(-c2c(C)cc(C)n(CC(C)C)c2=O)cs1 +CC(=O)C(NC(=O)CSc1ccccc1Cl)C(C)C +Cc1ccccc1C(C)NC(=O)C(C)S(=O)(=O)c1ccccc1 +O=C(c1cc(-c2cccc(F)c2)no1)N1CCc2ccccc2C1 +CN(CC1CC1)C(=O)NCC(=O)N1CCCCC1 +Cc1n[nH]c(C)c1CCC(=O)Nc1cccc(C#Cc2ccccn2)c1 +COc1ccc(NC(=O)C2(S(=O)(=O)c3ccc(C)cc3)CC2)cc1 +CCOC(=O)c1[nH]nc(-c2ccc(CC)cc2)c1N +Cc1noc(COC(=O)C(C)(C)c2ccccc2)n1 +Cc1cc(C)n(Cc2cccc(C(=O)N3CCCC3(C)C)c2)n1 +CCNc1nnc(-c2cnc(C3CCCO3)s2)s1 +Cn1c(-c2ccc(Cl)cc2)nnc1S(=O)(=O)CCCCC#N +COc1cc(CN(C(=O)NC2CC2)C2CC2)ccc1O +CCOc1cc(Br)c(C(=O)CC)cc1OCC +CC1CCN(c2c(F)cc3c(c2F)SC2=NCCN2C3=O)CC1 +CCNc1ccnc(NCC(=O)Nc2ccccc2C)n1 +COc1ccc(C(C)NC(=O)Nc2ccccn2)cc1F +COc1ccc(F)c(NC(=O)NC(C)CCc2cccn2C)c1 +COCC(C)OC(=O)c1sc(CC(C)C)nc1C +Cc1nn(C)c(N(CCO)C2CCCCC2)c1N +CC(=O)c1cccc(S(=O)(=O)NC(C)C(=O)NC2CCCC2)c1 +O=C(Nc1nc(-c2ccc(Cl)cc2)cs1)c1ccc(F)nc1 +CCC(=O)Nc1cc(C(=O)NCC(=O)NC)nn1-c1ccccc1 +COc1ccc(OC)c(NC(=O)CSc2ccccn2)c1 +CN(C(=O)Cc1n[nH]c(=O)c2ccccc12)C1CC1 +Cc1ccc(OCC(=O)NC2CCCc3nc(C)ncc32)cc1 +O=C1CCCN1CCC1CN(C(=O)c2cc[nH]n2)c2ccccc21 +COc1ccc(N2CCN(C(=O)CC(C)C)C(C)C2=O)cc1OC +Nc1ccc2ccnc(C(=O)Nc3ccc4c(c3)OCCO4)c2c1 +O=C(Nc1nccs1)C1CCN(Cc2nc3ccccc3[nH]2)CC1 +COC(=O)C(CO)NCc1csc2ccccc12 +COc1cccc(CCOc2cc(C)c(N)cn2)c1 +O=c1c2cnc3ccnn3c2ccn1C1CCCCC1 +O=C(NCc1nncn1C1CC1)Nc1cc(F)ccc1-n1cccn1 +CC(C1CC1)n1nccc1NC(=O)c1cnc(-c2cnn(C)c2)s1 +COc1ccccc1Oc1ccc2scnc2c1N +NS(=O)(=O)c1ccsc1C(=O)NCCC1=CCCCC1 +O=C(Cc1cccs1)NCC(=O)c1ccc(F)cc1 +Cc1onc(-c2ccccc2)c1C(=O)OCC(=O)NC(C)C +O=C(c1ccc(-c2ccc3ncccc3c2)nc1)N1CCOCC1 +CS(=O)(=O)NCC1Cn2c(-c3ccc(F)cc3)cnc2CO1 +Clc1ccccc1Nc1nc2nonc2nc1-n1ccnc1 +Cn1cc(CCC(=O)NCc2ccc(CN3CCCC3=O)cc2)cn1 +CCN(CC)C(=O)c1ccc(NC(=O)CNc2cccc(C)c2)cc1 +COC(=O)c1sccc1NC(=O)COc1ccc2c(c1)CCC2 +Cc1nc(C2CC3CCN(Cc4sccc4C)CC3O2)n[nH]1 +Cc1cccc(N(C)S(=O)(=O)c2cc(C(N)=O)n(C)c2)c1C +CC1CCN(C(=O)c2ccc(NC(=O)NC(C)C(C)C)cc2)CC1 +Cn1cccc1C1CCCN1C(=O)Nc1ccccn1 +CCc1ccc(C(=O)N2CCN(C(=O)c3cccc(O)c3)CC2)s1 +CC(C)NC(=O)N(C)C(c1cccc(F)c1)c1ccccn1 +COc1ccc(CCNC(=O)c2cc3n(n2)CCS3)cc1 +CCCCC(=O)N1CCc2nc(NC(=O)C3CC3)sc2C1 +CCC(=O)c1ccc2c(c1)N(S(C)(=O)=O)CC(C)(C)O2 +CC(=O)NCc1ccc(C(=O)NCCc2ccc3c(c2)OCO3)cc1 +CCn1cnnc1CNC(=O)NC(C)Cc1cccc(Cl)c1 +CCC(CO)Nc1ncnc2c1cnn2-c1ccc(C)c(Cl)c1 +Cc1ncsc1CN1CCCN(C(=O)COc2ccccc2)CC1 +CS(=O)(=O)c1ccc(C(=O)CSc2nncs2)cc1 +Cc1nc2ccc(NC(=O)c3cccc(N(C)C)c3)cc2o1 +CC(Sc1nc(-c2ccccc2F)n[nH]1)c1ccncc1 +CC(Sc1cc(C#N)ccn1)C(=O)NCCc1ccc(F)cc1 +CCC(OC)C(=O)NC(C)C(=O)NC1CCCC1 +COc1cccc(OCC(=O)N2CCN(Cc3cccs3)CC2)c1 +Cc1cccc(-c2nnc3n2NC(C)C(C)S3)c1 +CS(=O)(=O)c1ccc(C(=O)N2CCc3cc(F)ccc3C2)cc1 +CCOc1ncccc1C(=O)N1CCOC(CC)C1 +COCC(NC(=O)CCc1ccsc1)C(N)=O +CCOc1ccc(C(=O)Nc2ccc(S(N)(=O)=O)c(C)c2)cc1 +CCNC(=O)CS(=O)(=O)c1ccc(NC(C)=O)cc1 +CC(OC(=O)CSc1ccncc1)c1ccccc1 +Cc1cc(-c2nn3c(-c4ccccn4)nnc3s2)no1 +CC(C)c1cc(C(=O)N2CCCC3(CN(C)C(=O)O3)C2)cs1 +CCOC(=O)c1nccn1CC(=O)Nc1ccccc1C(F)(F)F +Cc1cc2c(cc1NC(=O)c1cccc(F)c1)n(C)c(=O)c(=O)n2C +Cc1ccc(-n2nnc(C(=O)Nc3nccs3)c2C(C)C)cc1 +CC(=O)NC(C(=O)NCc1c(C)noc1C)C1CCCC1 +COc1ccccc1C(=O)N1CCn2c1cc1ccccc1c2=O +Cc1nc(C(=O)N2CCCC2c2cccs2)cs1 +Nc1nonc1-c1nc2ccccc2n1CC(=O)N1CCCCC1 +COc1ccc(C2CCCN2c2cn[nH]c(=O)c2Cl)cc1 +O=C(Nc1cc(F)ccc1F)C1(c2cc(-c3ccco3)on2)CC1 +Nc1cccc2c(OCc3cccnc3)cccc12 +[H]N=c1n(CC(=O)OC)c2ccccc2n1Cc1ccccc1Cl +Cc1nc(-c2c(C(F)(F)F)oc3cc(O)cc(C)c3c2=O)cs1 +Cc1ccc(C)n1NC(=O)c1ccc(-n2cccc2)cc1 +COc1ccc(C(=O)n2ncc3c2c(C)nn3C)cc1OC +C=CCNC(=O)CCNS(=O)(=O)c1c(C)cc(C)cc1C +C=CCNc1nsc(C(=O)c2ccc(OC)cc2)c1N +CCN(CC)C(=O)c1ccccc1NC(=O)COc1cccc(C)c1 +C=CCCCN(C)S(=O)(=O)c1ccc2c(c1)C(=O)NCC2 +COC(=O)c1c(Cl)cc(OC)c(O)c1Cl +CCNS(=O)(=O)c1ccc(C(=O)N(C)Cc2ccc(C)o2)cc1 +Cc1cc(Br)c2c(c1)C(=O)CCCN2 +O=C1c2cc(Br)ccc2S(=O)(=O)N1Cc1ccco1 +Cc1ccc(C(=O)OCc2nc(N)nc(N(C)C)n2)c(O)c1 +Cc1cc(C(=O)NCC2CCC(C)(C)CC2)on1 +COc1ccc(C(=O)NCc2cccs2)cc1OC +CCCCN(CC)C(=O)C1CNc2ccccc2O1 +Cc1ccc(C)c(OCC(=O)N2CCC(O)C2)c1C +O=c1c2cccn2cnn1Cc1noc(C2CCCO2)n1 +CC(=O)Oc1cc(OC(C)=O)c2c(=O)c3ccccc3oc2c1 +CCN(CC)C(=O)C12CCC(C)(c3nc(C#N)c(C#N)nc31)C2(C)C +COc1ccc(C)cc1NC(=O)COc1ccccc1F +N#Cc1ccc(N2CCc3c(N)cccc3C2)c(F)c1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)NCCO)c12 +CCCC(C)(CO)NC(=O)NC(CC)c1ccc2c(c1)OCCO2 +CC(C)c1ncc(Cl)c(C(=O)N2CCNC(=O)C2)n1 +c1ccc(OCCOc2nnc3ccccn23)cc1 +CCC(CC)n1ncc(C(=O)N2CCN(CC3CCOC3)CC2)c1C +CC(=O)c1ccc(NC(=O)c2cc(C(F)(F)F)n(C)n2)cc1 +COc1ccc(Br)c(C(=O)Nc2cc(N)ccc2C)c1 +CCCN(Cc1ccccc1)C(=O)Nc1cnccc1C +Cc1nn(Cc2ccc(F)cc2Cl)c(C)c1N +O=C(c1cc2ccccc2[nH]1)N1CCN(CCO)CC1 +CCc1ccc(C(NC(=O)c2cnccn2)C(C)(C)C)o1 +CCc1c(C)sc2nc(C(C)C)n3c(=O)n(CC(N)=O)nc3c12 +CN(c1ccccc1C(N)=O)S(=O)(=O)c1ccccc1 +Cc1cc(C(=O)NC2(c3ccc(F)cc3F)CCOCC2)n(C)n1 +COc1cc(CNn2nnnc2N)ccc1OCc1ccc(F)cc1 +COCCCn1c2c(cc(C(C)(C)O)c1=O)CCCC2 +O=C(Cc1noc(-c2scnc2C2CC2)n1)NC1CCCC1 +CN(Cc1ccc2c(c1)OCCO2)c1ncnc2sccc12 +O=C(Nc1cccc(CN2CCCCC2=O)c1)Nc1ccccn1 +CCOC(=O)CN(C)C(=O)c1ccc(-c2ccco2)[nH]c1=O +CN(Cc1cc(=O)[nH]c2ccccc12)C(=O)c1ccc(F)cc1 +Cc1nc(NCC(O)CN2CCOCC2)sc1C +COCc1cccc(C(=O)N(C)Cc2ccc(SC)cc2)c1 +CC(Oc1cccc(F)c1)C(=O)NCC1CN2CCCCC2CO1 +O=C(NC(CO)c1ccccc1)c1cncc(F)c1 +Cc1cc(C)n(-c2ccccc2NC(=O)CNC(=O)C2CCCC2)n1 +CCC(Sc1nc2ccccc2o1)C(=O)Nc1nnc(C)s1 +CN1C(=O)C(C)(C)c2cc(C(=O)CCCO)ccc21 +O=C(c1cncn1-c1ccccc1)N1CCCc2ccccc21 +CCc1ccc(C(=O)N(C)Cc2cc(OC)ccc2OC)o1 +COC(=O)C1CC(F)(F)CCN1C(=O)OC(C)(C)C +Cc1cc(CN(c2ccccc2)S(=O)(=O)c2ccccc2)on1 +Cc1oc(-c2ccccc2)nc1C(=O)NCCN1CCCCCC1=O +COc1ccc(C(=O)c2sc3nc(C)ccc3c2N)cc1OC +Cn1c(C(=O)N2CCOCC2)cc2c(F)cccc21 +COC(=O)C1CCN(S(=O)(=O)c2cccc(C#N)c2)CC1 +O=C(CCC1CCCO1)Nc1ccc2ccccc2n1 +CC(Oc1ccc(C(C)(C)C)cc1)C(=O)NCC(=O)NC1CC1 +Cc1nc(C2CC3CCN(C(=O)c4c(C)noc4C)CC3O2)n[nH]1 +CCOc1ccccc1-n1nnnc1SC(C)C(C)=O +CC(C)C(CC(=O)N1CCN(S(N)(=O)=O)CC1)c1ccccc1 +Cn1c(=O)oc2cc(NC(=O)Nc3ccccc3Cl)ccc21 +CCCNC(=O)c1nnn(-c2ccc(OC)cc2)c1-c1cccnc1 +O=S(=O)(NCCCO)c1ccc2c(c1)CCO2 +Cc1noc(C2CCN(C(=O)c3ccc(N(C)C)nc3)CC2)n1 +CC(NC(=O)c1cccc(F)c1)C(=O)Nc1ccccc1 +COC(=O)C(C)NC(=O)Cc1cccc(OC(F)F)c1 +O=C(NCCC(=O)N1CCC2(CCCCC2)CC1)c1ccco1 +CC(Cc1ccc(Cl)cc1)N(C)C(=O)c1ccccn1 +O=C(Nc1cccnc1)N1CCN(Cc2cccc3ccccc23)CC1 +O=c1[nH]nc(CSc2nc3ccccc3c(=O)n2C2CCCC2)[nH]1 +O=C(COC(=O)c1cc2c(s1)CCC2)Nc1ccc(F)cc1 +O=C(Nc1nc2ccccc2[nH]1)c1ccc(NC(=O)C2CC2)cc1 +CN1CC(C(=O)N2CCCC2c2cccc(Cl)c2)CC1=O +Nc1nc(C(=O)Nc2nc3c(s2)CCCC3)n[nH]1 +O=C(c1ccccc1)C(O)(Cn1cnnc1)c1ccccc1 +COc1ccc(SCC(=O)Nc2c(C)nn(C)c2C)cc1 +CC(C)Oc1cccc(C(=O)NCc2ccc3c(c2)OCO3)c1 +Cn1ncc2c1CCc1sc(NC(=O)C3CCCC3)nc1-2 +Cc1ccc(NC(=O)c2cc(C(F)(F)F)n[nH]2)cc1F +Cc1cc(C(=O)NC(c2ccc(F)cc2)c2nccn2C)on1 +Cc1cccc(C(=O)Nc2nc(C)cc(C)c2-c2noc(C)n2)c1 +CCNc1oc(COc2cccc(Cl)c2)nc1C#N +CC1CN(C(=O)CNc2ccccc2-n2cccn2)CC(C)O1 +Cc1cccc(CN2C(=O)Cc3cc(N)ccc32)c1 +CCOC(=O)CCC(C)NC(=O)Nc1ccc(C)cc1 +Cc1cc(NC(=O)c2ccccn2)c(C)cc1NC(=O)c1ccccn1 +COC(=O)c1sc(NC(=O)c2cc(C(C)=O)c[nH]2)nc1C +CCNC(=O)N1CC(C(=O)NCCOC)C(c2cccc(F)c2)C1 +COc1ccc(-c2cc(C(C)=O)c(C)[nH]2)c(C)c1C +CC(=O)NCCC(=O)N1CCCc2cc(Br)cc(F)c21 +CCOc1cc2c(cc1OCC)CN(C(=O)C1CC=CC1)CC2 +COc1ccccc1CN(CCO)c1ccnc(-c2ccccc2)n1 +CC1(NC(=O)CCn2ccccc2=O)Cc2ccccc2C1 +CCC(C)C(NC(N)=O)C(=O)Nc1cccc(-c2nc(C)c(C)o2)c1 +CC(Cc1cccc(Cl)c1)NS(=O)(=O)c1cnn(C)c1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)NCc1ccccc1F +CC1CN(CC(C)(C)CCC#N)CC(c2ccccc2)O1 +COc1ccc(OC)c(C2CCCN2C(=O)COc2ccccc2)c1 +Cc1n[nH]c(C)c1CCOC(=O)c1cscn1 +C=CCn1c(C(C)NC(=O)COc2ccccc2)nc2ccccc21 +Cc1cnc(CNC(=O)CCSc2ccccn2)s1 +Cc1ccccc1C(=O)N1CC(OCc2ccc(Cl)cc2)C1 +Cc1noc(C)c1CNc1ccc(C(=O)N2CCC(C)CC2)cn1 +O=C(c1cc[nH]n1)N1CCC(Cc2ccc(F)cc2)CC1 +CCCN1C(=O)CCC2CN(C(=O)CCCn3cncn3)CCC21 +CC(=O)c1cccc(OC(C)C(=O)N(C)c2ccccc2)c1 +Cc1ccc(=O)n(C(C)C(=O)NCc2ccco2)n1 +NC(=O)c1cccc(S(=O)(=O)N2CCN(c3ccccc3)CC2)c1 +CCOC(=O)CC(O)c1ccc2c(c1)OCCCO2 +Cc1nc(-c2cc3cccc(C)c3nc2NCc2ccccn2)no1 +CC(=O)Nc1cc(NC(=O)N(C)CC(C)C)ccc1F +COc1ccc(S(=O)(=O)Nc2ccc(C)cc2)c(OC)c1 +CN(Cc1cnn(C)c1)C(=O)CCc1ccc2c(c1)OCO2 +CCc1cnc(NCc2c(C)nn(C)c2C)s1 +CSc1nsc(NC(=O)C(C)NC(=O)c2ccccc2)n1 +COc1cccc2c(=O)c(C(=O)Nc3nncs3)cn(C)c12 +Cc1nc(CNC(=O)CCC(=O)c2ccc(F)c(F)c2)c(C)s1 +CCc1nc2n(n1)CCCC2NC(=O)c1cc(-c2ccccc2)[nH]n1 +CC(=O)Nc1ccc(NC(=O)NCC2CC2C)cc1 +Cn1cc(C(=O)NCc2nc3cc(C(C)(C)C)ccc3o2)ccc1=O +COc1ccccc1N1CC(C(=O)Nc2nc(C)no2)CC1=O +O=S(=O)(NCc1ccccc1F)c1ccc(Cl)cc1 +Cc1c(-c2ccnc3cc(C(=O)Nc4nccs4)nn23)cnn1C +O=C(Nc1nnc(-c2ccc(F)cc2F)o1)c1ccc(F)cc1 +Cc1c(C(=O)Nc2ccc(C(N)=O)cc2F)cnn1-c1ccncc1 +CCc1ccc(NC(=O)COc2c(OC)cccc2C(N)=O)cc1 +COC(=O)c1cc(C(=O)NC2(C)Cc3ccccc3C2)ccn1 +CCn1nc(C)c2c(C(=O)Nc3nn(C)cc3Cl)cc(C)nc21 +Cc1c(C(=O)N(C)C(C)c2ccc(S(C)(=O)=O)cc2)cnn1C +COCC(NC(=O)C1(c2ccccc2)CCC1)C(N)=O +CCOCC(O)CN1CCN(C(=O)C(C)c2cc(C)oc2C)CC1 +CCC(=O)N1CCc2cc(-c3nc(-c4ccc(C#N)cn4)no3)ccc21 +Cn1cccc1C(=O)NCCc1ccc(C(F)(F)F)cc1 +Cc1cc(S(=O)(=O)NCc2nc(-c3cccnn3)no2)ccc1F +NS(=O)(=O)NCc1cccnc1OC1CCCC1 +COc1ccc(CNc2ncnc3[nH]nc(SC)c23)cc1OC +COCCNC(=O)CN1CCN(C(=O)c2sccc2C)CC1 +Cc1ccc(NC(=O)NCC2CCN(S(C)(=O)=O)CC2)cc1C +Cn1c(=O)n(CCC(=O)NCc2ccc(O)cc2)c2ccccc21 +Cc1cccc(CNC(=O)NCCN(C)C(=O)OC(C)(C)C)c1 +CC(Cn1ccnc1)NC(=O)c1sccc1N +CN(CCc1ccccc1)Cc1cc(C(=O)N2CCCC2)no1 +COc1cc(N2CCC3(CC2)CNc2ccccc23)ncn1 +C=CCn1c(CNC(=O)c2ccco2)nnc1SC +COCCOc1ccccc1NC(=O)c1cnc(C)cn1 +CC(CNC(=O)c1ccc(-n2ccnn2)cc1)c1ccc(F)cc1F +Cc1cc(C(=O)N2CCN(CCO)CC2)c(C)n1Cc1ccccn1 +CCC(CC(=O)N1CCN(C2CCCC2O)CC1)c1ccccc1 +CCCOc1ccc(CCC(O)c2ccccn2)cc1 +CCc1onc(C)c1C1CCCN1C(=O)c1cccs1 +CCc1cc(CN(C)C(=O)c2c(-c3ccccc3)noc2C)on1 +Cc1ccc(C(=O)N(CC(F)(F)F)c2ccccn2)s1 +Cc1ccsc1C(=O)OCC(=O)NCC1CCCCC1 +CC1CCCC(NC(=O)NCc2ccc(CN3CCCC3=O)cc2)C1 +COc1ccc(NC(=O)COc2ccc(C(C)=O)cc2)cc1 +CN(Cc1n[nH]c2c1CCCC2)C(=O)Nc1ccc2c(c1)OCCO2 +Cc1cccc(NC(=O)c2cc3c(nc4sccn43)s2)n1 +Cc1ccc(C)c(NC(=O)CCn2ccccc2=O)c1 +CCCN(C(=O)N(C)C)C(C)C(=O)Nc1ccccc1 +Cc1noc(COC(=O)c2cc(Br)cnc2N(C)C)n1 +COc1ccc(-c2ccnc(C)n2)c2cccnc12 +C#CCn1c(=NC(=O)C2CCC2)sc2cc(OC)c(OC)cc21 +CC(C)c1nc(-c2ncn[nH]2)n(-c2cccc3cccnc23)n1 +O=S1(=O)N=C(Nc2ccc3c(c2)oc2ccccc23)c2ccccc21 +O=S(=O)(c1ccc2c(c1)COC2)N1CCCC1Cn1ccnc1 +O=C(NCCOc1ncc(Cl)cc1Cl)c1ccncc1 +CCCOc1cc(Br)cn(CC#N)c1=O +COC(=O)C1CCCCCC1NC(=O)c1ccoc1 +CN(C)c1ccc(-c2nnc3[nH]c4ccc(N)cc4n23)cc1 +CC(NC(N)=O)C(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +Cc1nc(CCNC(=O)C2CC(=O)Nc3ccc(F)cc32)sc1C +CCc1nc2n(n1)CCCC2NC(=O)Nc1c(C)cccc1C(C)C +NC(=O)c1ncc(Br)c2ccc(Cl)cc12 +Cc1ccc(S(=O)(=O)NCc2ccccn2)c(C)c1 +O=C(Nc1cccc(C(=O)N2CCCC(O)C2)c1)C1CCCO1 +COc1ccc(Cc2nc3cccc(N)c3o2)cc1 +Cc1cc(OC(=O)c2cnccn2)cc(C)c1Cl +NC(=O)c1[nH]nc2c1CCOc1ccc(Br)cc1-2 +Cc1ccc(NC(=O)c2csc(Cc3ccccc3)n2)nc1 +COc1cccc(CNc2cc(Cl)ccc2O)n1 +CCCN1C(=O)COc2cc(NCc3ccc(OC)cc3)ccc21 +CN(C)C(=O)c1ccccc1NCc1ccc(C(F)(F)F)cc1 +COc1ccccc1OCC(=O)N1CCC(Oc2cnccn2)CC1 +O=C(NCCCOCC1CCCO1)NC1CCCCC1 +Cc1cc(C(=O)N(CC2CCCCC2)C2CC2)c2c(C)noc2n1 +CCCn1c(-c2ccc(C)cc2)ccc(CO)c1=O +COc1ccc(OC)c(CC(=O)NC(C)c2ccncc2)c1 +COCCNC(=O)c1cnn2c(C(F)F)cc(-c3ccccc3)nc12 +C#CCNCc1cc(Cl)c(OC)c(OCC)c1 +CCc1csc(-c2cn(CC(=O)Nc3cccc(Cl)c3)cn2)n1 +Cc1occc1COC(=O)c1cn(C)nc1-c1cccs1 +COC(=O)c1ncn(CC(=O)N(C)Cc2c(F)cccc2Cl)n1 +O=C(Nc1ccc(Cl)cc1Cl)c1cc2n(n1)CCCO2 +CCc1cc(C(=O)Oc2cccc(C(N)=O)c2)sc1C +Cn1cc(CNc2cccc(S(C)(=O)=O)c2)cn1 +O=C(Nc1cc[nH]n1)c1cc(=O)[nH]c2ccc(Br)cc12 +CN(C)c1ccc(-c2nnc3sc(-c4cccnc4)nn23)cc1 +Cn1cc(CCNC(=O)C2CCN(C(=O)C3CC3)CC2)cn1 +O=C(Cc1ccccc1)N1CCN(c2cnn3cnnc3c2)CC1 +C#CCNC(=O)N(Cc1ccc(C(=O)NC2CC2)cc1)C1CC1 +CC(=O)c1csc(C(=O)Nc2cc(C)cc3cccnc23)c1 +O=S1(=O)N=CN(c2ccc3c(c2)CCC3)c2ncccc21 +COCc1nnc(NC(=O)CCCc2nnc3ccccn23)s1 +CCCn1nc(CNc2ccc(F)cc2)[nH]c1=O +COCC(C)NC(=O)C1CN(Cc2ccccc2)CCO1 +Cc1cc(C(=O)NC(C)c2nc3ccccc3[nH]2)c2c(C)nn(C)c2n1 +CCOC(=O)C1(NC(=O)c2cc(F)cc3[nH]cnc23)CCCC1 +CC(C)CNC(=O)C(C)NC(c1ccccc1)C(C)C +CCCCCC(NC(=O)c1cnc2ccccn2c1=O)c1ccccc1 +CC(=O)NCCCS(=O)(=O)c1nccn1-c1cccc(F)c1 +COCCc1ncc(CNC2(c3ccc(Cl)cc3)CC2)cn1 +CC1CCCCC1NC(=O)c1ccc(=O)n(Cc2ccc(F)cc2)n1 +CCc1ccc(NC(=O)COc2cccc(NC(=O)OC)c2)cc1 +Cc1cc2ccccc2n1CC(=O)N1CCCCCC1 +CCc1ccc(C(C)NC(=O)c2ccccn2)cc1 +O=C(NCC1CCCO1)NC1CCOc2ccccc21 +Cc1ncc(C(C)NCC(c2ccc(F)cc2)N2CCOCC2)s1 +CCOc1ccc(Br)cc1C(=O)NCc1ccccn1 +O=C(Nc1nncs1)c1ccc(C(=O)Nc2nncs2)s1 +Cc1cc(C(=O)N=c2[nH]c3ccccc3[nH]2)nn1C +Cc1[nH]nc2c1NC(c1cc(F)c(F)c(F)c1)NC2=O +CCn1nc(C)cc1-c1nn2c(Cc3ccc(F)cc3)nnc2s1 +COc1ccnc(NC(=O)c2ccccc2-n2cccn2)c1 +OCc1cccc(Nc2ncnc3sccc23)c1 +NC(=O)C1CN(C(=O)C2(c3ccc(F)cc3F)CCCC2)CCO1 +CCOc1ccc(SCC(=O)Nc2cc[nH]n2)cc1 +COCCNC(=O)c1cncc(-c2cc(OC)ccc2OC)c1 +Cc1nnc2n1CC(NC(=O)c1ccc(Oc3ccccc3)nc1)CC2 +O=C(CSc1nnnn1C1CCCCC1)NCCc1ccccc1 +CCc1noc(CN(C)Cc2cnc3cc(C)ccn23)n1 +CN(Cc1nccn1C(F)F)C(=O)c1ccc(Cn2cccn2)cc1 +COCC1CCN(C(=O)c2cc(C)nc3c(C)c(C)ccc23)C1 +CCOC(=O)CCS(=O)(=O)Nc1ccc(Br)cc1 +O=C(CNC(=O)c1ccccc1)Nc1nnc(-c2ccccc2)s1 +Cc1ccc2oc(C(=O)NCc3nc[nH]n3)cc2c1 +COC(=O)c1ccc2ccn(CC3CCCO3)c(=O)c2c1 +Cc1nn(-c2ccccc2)c(Cn2cnc(C#N)n2)c1C#N +CC(=O)N1CCCC1c1nc(N)ncc1-c1ccc(F)cc1 +O=C(Nc1ccc2c(c1)OCO2)c1cc(=O)nc2cccnn12 +CC(Nc1cc(-n2cccn2)nc(N)n1)c1nnc2n1CCC2 +CC(=O)NC(C)C(=O)NCc1cnn(Cc2ccccc2)c1 +Cc1cnc(NC(=O)N2CCc3cc(Br)ccc32)s1 +O=C(c1csc(-c2cccs2)n1)N1CC2C3CCC(O3)C2C1 +CC(=O)NCC(=O)NCc1ccc(Cl)cc1Cl +N#CC(CCC(=O)NC1CCCC1)c1ccccc1Cl +Cc1cc(CNC(=O)Nc2nc(-c3cccnc3)cs2)ccc1F +N#Cc1cccc(C(=O)N2CCC(c3nc4ccccc4o3)CC2)c1 +Cc1n[nH]c(SCCC(=O)NCc2ccc3ccccc3c2)n1 +CCOc1ccc(-c2cnn(C)c(=O)c2C(C)=O)cc1CC +CCOc1cc(C#N)c(Br)cc1OCCO +O=C(NC1CCCCC1)N1CCCCC1c1nncn1CC1CC1 +Cc1cc(F)ccc1NC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +COCC1c2nnn(CC3CC3)c2CCN1C(=O)N(C)C +CC(C#N)CN(C)C(=O)NC1CCSc2ccc(Cl)cc21 +COc1ccc(C(NC(C)=O)C2CCOCC2)cc1 +CC(C)CC(C)(NS(=O)(=O)c1ccc(C#N)cc1)C(N)=O +O=C(c1ccc(F)cc1F)N(Cc1ccco1)c1ccccn1 +COc1cc(N)c(Cl)cc1C(=O)OCC(=O)NCC(C)C +NC(=O)c1cc(Cl)ccc1NC(=O)COC1CCCCC1 +Cc1ccc(CN2CCOC(c3nccs3)C2)cc1C +O=C(Cc1ccon1)NCc1ccc(OCc2ccccn2)cc1 +CCCC1CCC(NC(=O)Cn2ccccc2=O)CC1 +CCOC(=O)c1c(C)[nH]c(-c2cccc(OC)c2)c1N +CC1CCCC(NC(=O)c2nn(C)cc2Br)C1C +CC(=O)NCCNC(=O)Nc1ccccc1C1CC1 +CCNC(=O)c1nc(-c2oc3c(C)cccc3c2C)no1 +CC(C)c1nnc(NC(=O)c2cn(C)c3c(F)cccc3c2=O)s1 +O=C(COC(=O)c1cc(F)ccc1F)Nc1cc(F)cc(F)c1 +CN(C)c1ccc(C(=O)NCC#Cc2ccc(C(N)=O)cc2)cc1 +CCCCc1nnc(NC(=O)CSc2ccc(F)cc2)s1 +CC(=O)NCCNC(=O)c1ccc(N)c(OCC(N)=O)c1 +O=C(Nc1cccc(CNc2ncnc3[nH]cnc23)c1)C1CCCO1 +COCCOCCNC(=O)NC1(C)Cc2ccccc2C1 +CN(C)C(=O)CNc1ccc(SC2CCCC2)cc1 +O=c1c(C(F)(F)F)cccn1Cc1ncn(-c2ccccc2)n1 +NC(=O)C1CCCN1C(=O)Cc1ccc(-n2cccn2)cc1 +Cc1ccc(CCC(=O)NCC(=O)Nc2nc(C3CC3)cs2)cc1 +CCC(C)Oc1ccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +CC1CCCC(CNC(=O)NC(C)C2CCCO2)C1 +c1cc(CN(Cc2cnc(N3CCCC3)s2)C2CC2)ccn1 +Oc1ccc(Cl)c2c1CCNC2c1ccncc1Cl +CCCOc1cc(C)ccc1NC(=O)c1ncn(-c2ccccc2)n1 +CN(C)C(=O)CNC(=O)Nc1cccc(OC(F)F)c1 +Cc1cc(F)ccc1NC(=O)c1ccc(Br)cn1 +COc1ccc(CCC(=O)N(C)CCC(F)(F)F)cc1 +CN(Cc1csc(-c2ccoc2)n1)CC(O)c1ccc(F)cc1 +C=CCNC(=O)NC1CC(=O)N(c2cccc(F)c2)C1 +Cc1cccc(SC(C(N)=O)c2ccc(F)cc2)c1 +CCc1ccc(CCC(=O)N2CCN(Cc3cc(C)on3)CC2)cc1 +COC(=O)c1scc(-c2cccc(OC)c2)c1N +CC(=O)c1ccc(C(=O)Nc2cccc(-c3nc(C4CC4)n[nH]3)c2)cc1 +Cc1c(C(=O)Nc2ccc(C(=O)NC3CC3)c(Cl)c2)cnn1C +CCc1ccc(NC(=O)Cn2c(N)nc(C)c(C)c2=O)cc1 +O=C(CNC(=O)c1c[nH]c2ccccc2c1=O)NCc1ccco1 +CC(C)(C#N)NC(=O)COc1ccc(Cl)cc1 +O=c1[nH]c2c(=O)oc3ccccc3c2n(Cc2ccccc2)c1=O +COc1ccccc1NC(=O)CSc1nccc(=O)[nH]1 +CC(C)CCNC(=O)c1ccc2c(c1)CCCN2S(C)(=O)=O +Cc1ccc(O)c(NC(=O)c2nnc(CN)c3ccccc23)c1 +CC(C)(c1cccc(F)c1)c1nc(-c2ccc(C#N)cn2)no1 +Cc1cc(NC(=O)Cc2ccc(S(=O)(=O)C(F)F)cc2)no1 +CC1CCCN(C(=O)NCc2ccnc(-n3cccn3)c2)C1 +CC1CCC(N(C)C(=O)NCC(=O)N(C)CCc2ccccn2)CC1 +OC1(c2cccnc2)CCN(Cc2nc3ccccc3[nH]2)CC1 +CCOC(=O)C(O)Cc1cc(Cl)ccc1OC +Cc1cc(NCC2CCCO2)n2nc(C)c(-c3ccccc3)c2n1 +CC(=O)c1ccccc1NC(=O)Cc1cccc(F)c1 +CC(C)CN(CC(F)(F)F)C(=O)Cn1cnc2c(cnn2C)c1=O +Cc1nc2c(C#N)cnn2c(C)c1CCC(=O)OCC1CCCO1 +Nc1ccccc1NC(=O)Cn1c(=O)cnc2ccccc21 +CCCNC(=O)C(C#N)Cc1c(F)cccc1Cl +CC(NC(=O)N(C)C(C)C1CC1)C(=O)N1CCCCC1C +COCCCNc1ncnc(Oc2cccc3cccnc23)c1N +FC1(F)CCN(Cc2ccncc2)CC12CCN(c1cnccn1)C2 +Cc1cc(CSc2nnc(-c3ccccc3)n2C)no1 +COC(=O)C1(c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1 +CC(NC(=O)c1cc(Cl)ccc1O)c1ccco1 +CC(C)C(=O)N1CCC(c2nc3cccnc3n2C)C1 +CCC(=O)Nc1ccc(O)c(C(=O)Nc2cccc(F)c2)c1 +O=C(CC(F)(F)F)Nc1cc(C#CCO)ccc1Cl +Cc1ccc(-n2[nH]c(C(=O)NCCOc3cccnc3)cc2=O)cc1 +Cc1nc(C2CC3CN(C(=O)c4cccn4C)CCC3O2)sc1C +CCN(CC(C)C#N)C(=O)CNc1cc(NC(C)=O)ccc1F +O=C(NCc1cn2ccccc2n1)C1CCN(C(=O)C2CC2)CC1 +CCC(C)(C#N)NC(=O)c1cnn(-c2ccccc2C)c1 +CCOC(=O)c1c(C)[nH]c(C(=O)NC(C)c2ccccn2)c1C +CC(=O)N1CCCC1c1nccnc1-c1ccc(F)cc1 +Nc1ccc(F)c2ccnc(C(=O)NC3CCC(O)CC3)c12 +Cc1ccc(C)c2c(=O)c(Br)c[nH]c12 +CC(OC(=O)c1cscn1)C(=O)Nc1cccc2ccccc12 +CC1=C(C(=O)NCc2cn3nc(C)sc3n2)C(C)NC(=O)N1 +Cc1ccccc1NC(=O)CCC(=O)N1CC(=O)Nc2ccccc21 +CCc1cc(C(=O)NCC(C)(C)C(N)=O)sc1C +CCCC(C)(C)NC(=O)Nc1ccccc1-n1nc(C)nc1C +COc1ccc(CN(C)C(=O)NCC(C)Oc2ccccc2)cc1O +Cc1ccc(C2OCCCC2CNC(=O)NCC(O)C2CC2)cc1 +O=C(Cc1cccs1)N1CCC(c2cccs2)CC1 +CCN(Cc1ccncc1)C(=O)c1n[nH]c2c(Cl)cccc12 +COc1cccc(C(=O)Nc2cc(-c3ccco3)no2)c1OC +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cncn1-c1ccc(F)cc1 +Cc1cc(C)nc(-n2nc(C)cc2NC(=O)c2c(F)cccc2F)n1 +CCOC(=O)C(C)OC(=O)c1cc(N)c(F)cc1Br +CCS(=O)(=O)N1CCCC1C(=O)c1ccc(C(C)C)cc1 +CC(C)(CNC(=O)N1CCOC2(CCOCC2)C1)c1ccncc1 +O=C(Nc1ccc(-n2ccnc2)nc1)c1cc2c([nH]c1=O)CCCCC2 +Cc1csc(=O)n1CCC(=O)NCC1COc2ccccc2O1 +CCCOC(=O)C(C)N1C(=O)COc2cccc(N)c21 +CC(Sc1nncn1C)C(=O)NC1(C(N)=O)CCCCC1 +CCN(C(=O)Nc1nccs1)C(C)c1cccc(O)c1 +CC(C)Nc1ncc(C(=O)NC(c2ccccc2)c2ccncc2)cn1 +CCNC(=O)c1ccc(NCC(=O)Nc2cccc(C)c2C)cc1 +CC(Sc1nc2ccccc2n1C)C(=O)NC1CC1 +CN(C)c1ccccc1NC(=O)N1CCC(Oc2ccccc2)CC1 +O=C(COc1ccccc1F)Nc1nc2c(s1)CCC2 +COc1cccc(CC(=O)Nc2ccc(NC(=O)C(C)C)cc2)c1 +CN(C)C(=O)CCNC(=O)NCC(=O)N1CCc2ccccc2C1 +CCC(=O)N1CCC2(CC1)CC(NC(=O)NC)c1cc(C)ccc12 +O=C(CCOc1ccccc1)Nc1cccc(CO)n1 +CCCNc1nnc(-c2csc(-c3ccco3)n2)s1 +Cc1cccc(C(C)NC(=O)c2cc(C(N)=O)cs2)c1C +Cc1ccc(CNC(=O)c2cnn3c4c(cnc23)CC(C)CC4)cc1 +O=C(NCc1cnn(Cc2ccccc2)c1)c1ccc(=O)[nH]c1 +CC1CCN(Cc2cc(=O)n(C)c(=O)n2C)c2ccccc21 +COc1ccc(OC)c(CN2CCN(C(=O)CC3CCCC3)CC2)c1 +N#Cc1ccc(NC(=O)c2ccc(S(=O)(=O)NC3CC3)cc2)cc1 +N#Cc1c(N)c(C#N)c(-c2ccc(O)cc2)c2c1CCCC2 +CN(C(=O)C1CCC1)c1cccc(NC(=O)C2CCC2)c1 +O=C1CC(c2ccncc2)C2(CCN(c3ncccn3)CC2)N1 +CC(C)Cc1ccc(C(C)NC(=O)NCCC(=O)N(C)C)cc1 +CC(=O)c1ccccc1NC(=O)Nc1ccccc1 +Cc1nc(CC(=O)N2CCN(C(C)c3ccccc3F)CC2)cs1 +O=C(c1cccnc1)N1CCCn2c(CN3CCOCC3)nnc2C1 +Cc1ccc(NC(=O)NCc2nc3ccccc3[nH]2)cc1 +COc1ccc(CNC(=O)c2cn(CC(=O)N(C)C)nn2)cc1 +CC(C#N)CN(C)C(C)C(=O)Nc1nccs1 +Cc1cc(C(=O)N(C)c2ncccc2Br)no1 +CC1(OC(=O)c2cc(N3CCCC3=O)ccc2Cl)CCC1 +Cc1nc(NCc2cccs2)c2cc(C)sc2n1 +O=C(Cc1c[nH]c2ccccc12)Nc1nc2ccccc2[nH]1 +CCOC(=O)C1C(O)CCN1C(=O)OC(C)(C)C +Cc1oncc1C(=O)NC1CCC2(CCC(=O)N2CC2CC2)CC1 +Cc1cccc(CN2CCCC3(CCN(C(=O)C4CC4)C3)C2=O)c1 +COc1ccc(CC2CN(Cc3cccc(C(C)=O)c3)CCO2)cc1 +Cc1c[nH]c(CN2CC3CCC(C2)N(CC2CC2)C3=O)c(C)c1=O +Cn1cnc(CNC(=O)c2c(F)cccc2Br)n1 +O=C(CN1CC(c2ccccc2)CC1=O)NCCc1ccccc1 +COCc1ccccc1NC(=O)N1CCNC(=O)C1 +COC(=O)c1cccc(CC(=O)Nc2nc3ccc(F)cn3n2)c1 +CCC(C)NC(=O)CCNC(=O)NC1CCCCC1 +Cn1c(SCCCCC(N)=O)nc2sccc2c1=O +O=C(C1CCOCC1)N1CCOC(Cc2ccccc2)C1 +O=C(NCc1ccco1)C1CCCN1C(=O)Nc1cn[nH]c1 +CCCC(NC(=O)C(C)NC(=O)C1CCOCC1)C1CCCCC1 +CCCC(=O)N1CCCC1C(=O)c1ccc(OC)c(C)c1 +CCCOc1ccc(S(=O)(=O)Nc2ccncc2)cc1C +CCc1nc2ccccc2n1CC(=O)Nc1cccc(C)c1 +CC(C)Oc1ccc(C(=O)NCCNC(=O)c2ccc(F)cc2)cn1 +NC(=O)N1CCC(NC(=O)c2ccc(F)cc2)CC1 +CCOC(=O)CC(C)CNC(=O)N1CCC(c2ccn[nH]2)CC1 +CCOc1ccccc1C(=O)N(CC)CC(C)C#N +CC(C)C1(O)CN(C(=O)C2C(C)(C)C2(C)C)CC1C +Cc1c(CNC(=O)NCCc2nccn2C(F)F)oc2ccccc12 +CCc1nnc(C2Cc3ccccc3CN2Cc2nc(C)no2)o1 +O=C(NCC1CCC(C(=O)NC2CC2)CC1)c1cccc2ccoc12 +CNC(=O)C1CN(C(=O)c2ccsc2)c2ccccc2O1 +CC(CC(=O)N1CCc2ncc(Cl)cc2C1)n1cncn1 +CCN(CC)C(=O)C(c1ccccc1)N(C)CCC#N +CCC1CCCC(NC(=O)NCCNC(=O)c2ccccc2)C1 +CC(C)c1cc(Br)ccc1NC(=O)NCCCO +CCOC(C)c1noc(CN(C)Cc2cc(Cl)cc(Cl)c2)n1 +COc1cccc(-n2ccnc(NCc3cccs3)c2=O)c1 +CC(C)(CNC(=O)OC(C)(C)C)NC(=O)Cc1c[nH]c2ccccc12 +Cc1cc(C)n2nc(CC(=O)N(CC(C)C)CC(C)C)nc2n1 +Cc1cccc(OCCN(C)C(=O)c2ccc3cc[nH]c3c2)c1 +Cn1ccc2cc(C(=O)NCCc3ccccn3)ccc21 +CCc1noc(CC)c1CNC(=O)c1cc(F)c(F)cc1Cl +CC(=O)C1(c2ccccc2)CCN(S(=O)(=O)c2cn(C)cn2)CC1 +Cc1cc(CN(C)C(=O)c2cnn(-c3ccc(Cl)cc3)c2)no1 +O=C(c1ccc(-n2cccn2)cc1)N1CCC(Nc2ccccc2)CC1 +O=C(NCc1ccco1)C1CCN(c2cnc3nccnc3c2)CC1 +CCC(=O)NCc1ccc(OCC2CCCO2)c(OC)c1 +Cc1ccc(CC(=O)N2CCCS2(=O)=O)s1 +Cn1c(=O)c2c(ncn2CC(=O)NCCCO)n(C)c1=O +Nc1nc2cc(Br)ccc2n1CC1CCCCO1 +CN(Cc1ccccn1)C(=O)c1nc2ncc(Br)cn2n1 +Cn1cnc2cc(OC(=O)c3cc(=O)c4ccccc4o3)ccc21 +Cc1ccc2[nH]nc(C(=O)NCCCN3CCCCCC3=O)c2c1 +CC1CCCN(C(=O)c2cccc(S(=O)(=O)NC(C)C)c2)C1 +COc1cc(C2NC(=O)c3cccc(C)c3N2)ccc1OCC#N +Cc1ccc(NC(=O)CN(C)C(=O)c2cccc(-n3cccc3)c2)cc1 +COCCNC(=O)N1CCN(c2ncnc3c2cnn3C)CC1 +Cc1cc2nc3c(cn2n1)C(=O)CC(c1cccs1)C3 +COc1ccc(CC(=O)Nc2nc(C)c(C)s2)cc1 +COc1ccnc(N2CCN(C(=O)CCCn3cccn3)CC2)n1 +O=C(NCCO)NCC(c1ccccc1Cl)N1CCOCC1 +COc1cc(C(=O)NCc2cnc(C)s2)ccc1OC(C)C +O=C(OCc1ccccc1F)c1ncn(-c2ccccc2)n1 +CC(=O)Nc1cc(C(=O)OCc2cncs2)ccc1F +CCC(O)CN1CCN(C(=O)c2cccn2C)CC1 +O=C(Nc1ccc(OC(=O)C2CCOc3ccccc32)cc1)C1CC1 +Cc1nc(-c2c[nH]c(C(=O)NCC#Cc3ccccc3)c2)cs1 +CCCC(=O)Nc1ccc(CNC(=O)c2cccnc2OC)cc1 +Cn1nnnc1SCC(=O)Nc1ccccc1C(=O)NC1CC1 +O=C(Nc1ccccn1)c1cc(=O)c(OCc2ccccc2F)co1 +COc1cc(C)c(-c2cc(=O)c(C#N)c[nH]2)cc1C(C)C +CCc1nsc(N2CCc3sccc3C2)n1 +CCSc1ccc(-c2cn3cccc(N)c3n2)cc1 +Cc1ccnc(C(NC(=O)c2cnc3cccc(C)n3c2=O)C2CC2)c1 +Cc1cc(C(=O)NC2CCCN(c3ccccc3F)C2=O)no1 +Cc1ccc(CNC2CCOC2c2ccc(F)c(F)c2)nc1 +O=C(OCc1ccccc1)c1ccc(N2CCOCC2)cc1F +Cc1nn(C)c(C)c1-c1cc(C)c2nc(N)nn2c1 +CC(C)Cn1nc(C(=O)NCC(C)CC(C)O)c2ccccc2c1=O +O=C(COc1ccccc1)Nc1c2c(nn1-c1ccccc1)CCC2 +COc1cc2c(c(OC)c1O)C(c1ccnnc1)NCC2 +Cc1ccc(CC(=O)Nc2c(C)cnn2CC2CC2)s1 +Cc1nc(Cc2noc(C(C)(C)CNC(=O)OC(C)(C)C)n2)no1 +O=C(NCc1ccccc1)N1CCC(n2cnc3cccnc32)CC1 +CC(=O)c1ccc(NC(=O)NCCC(C)(C)C)cc1 +COc1ccc(C(=O)Nc2cccc(F)c2F)nn1 +Cn1cc(CCNC(=O)NCCc2c(Cl)cccc2Cl)cn1 +CS(=O)(=O)N1CC(C(=O)NCc2ccccc2Cl)C1 +CCc1nc(CNc2ccc(C)c(C(=O)N(C)C)c2)cs1 +Cc1ccc(-c2nnc(SC(C)C(=O)N(C)C)n2N)cc1 +CCCc1nc2ccccc2n1CC(O)c1ccccc1 +CCC(C)c1ccccc1OCc1[nH]nc(C)c1CO +O=C(CCn1cccn1)NCC(=O)Nc1ccc(Cl)cc1 +CCN(CC)C(=O)NC1CCOc2ccc(Br)cc21 +CCOCCSc1nc(C)nc2sc(C)c(C)c12 +NC(=O)COC1COC2C(NC(=O)Nc3ccccc3)COC12 +CCCn1ccc(CNc2ccc(F)cc2F)n1 +CC(=O)Nc1ccc(O)c(C(=O)NCCOc2cccc(C)c2)c1 +COc1ccc(S(=O)(=O)NC2CCC(O)CC2)cc1 +Nc1cccc2ccc(CC(=O)Nc3cccc(F)c3)nc12 +CCCOc1c(OC)ccc2c1C(C1CC(=O)C1)NCC2 +O=C(c1cccs1)C1C2C(=O)C3OCC(O3)C12 +CC1=Nc2ncnn2C(=O)C1CCOC(=O)Nc1ccc(C)cc1 +CCn1cc(CNc2cc(OC)c(Cl)cc2OC)cn1 +CC1CN(Cc2ccccc2)CCN1C(=O)c1ccccc1F +Cc1ccc(-c2nnc(SCC(=O)NCC3CCCO3)o2)cc1C +CS(=O)(=O)c1ccc(Cl)c(NC(=O)Cc2cccc(F)c2)c1 +CN(CC(C)(CO)CO)C(=O)c1ccc(C(C)(C)C)s1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1ncn(-c2ccccc2)n1 +O=C(OCCc1cccnc1)c1ccc(Cn2ccccc2=O)o1 +O=S(=O)(Cc1nc2ccccc2s1)c1ccccn1 +COc1ncccc1CNC(=O)N(C)CCOc1ccc(Cl)cc1 +c1cc2c(cc1-c1[nH]nc3c1CNCC3)ncn2C1CC1 +CC(O)c1ccc(OCC(=O)Nc2ccccc2)cc1 +CCC(CC)n1nc(NC(=O)c2cnc3c(c2)ncn3C)cc1C +CCC(C)C(C)NC(=O)CCc1c(C)nc(SC)[nH]c1=O +CC1c2ccsc2CCN1C(=O)CCN1CCOC1=O +Cc1ccc(C2CC2C(=O)N(Cc2ccncc2)C2CC2)s1 +CCCNC(=O)c1ccc(S(=O)(=O)NC(C)C)cc1 +CC(=O)NC(CC(=O)N(C)Cc1c(C)noc1C)c1ccccc1 +Cc1ccc(C(=O)NCc2ccc3c(c2)OCO3)c(=O)[nH]1 +Cc1cc2ccccc2n1CC(=O)NCc1nc2ccccc2n1C +CCSc1nnc(N)n1CC(=O)Nc1ccccc1OC +COc1ccc(CCC(=O)N2Cc3cncnc3C2)c(OC)c1OC +COc1cc(-c2c(C)c[nH]c(=O)c2C#N)ccc1O +Cc1cc(C)cc(COc2ccc(C(=O)NCCO)cc2)c1 +CCCn1nc(C(=O)N(Cc2ccco2)CC(F)(F)F)ccc1=O +CCOc1ccc(NC(=O)c2cccc(OC)c2F)c(C(N)=O)c1 +COc1ccc(C)c(NC(=O)c2scnc2C2CC2)c1 +O=C(NCC(F)(F)F)Nc1cccc(COCC2CC2)c1 +CCn1cc(C(=O)NCCO)c(=O)c2cc(Cl)ccc21 +O=C(Nc1cccc(Cl)c1)c1cc(-c2ccncc2)[nH]n1 +Cc1nc(Cc2noc(C=Cc3cnc4ccccc4n3)n2)no1 +O=C(CCn1cncn1)NC(c1ccccc1)C(F)(F)F +COC(=O)C(CC(C)C)NC(=O)N1CCOCC1 +N#Cc1ccc(C2Nc3ccccc3C(=O)N2C2CCCC2)cc1 +CCc1nc(CC(=O)NCc2ncc(-c3ccccc3)o2)cs1 +O=c1[nH]c2ccccc2nc1-c1c[nH]c2ccccc12 +Cc1nnc(NC(=O)N(Cc2ccccc2)C(C)C)s1 +COCCN(C)S(=O)(=O)c1cnn(-c2ccccc2)c1 +C=CCc1c(O)c(OC)cc2c1C(CC#N)NCC2 +O=C(NCCCNC(=O)c1cccc(F)c1)NC1CC=CC1 +COc1cccc(-n2cnnc2CCn2cccn2)c1 +Cc1cccc(NC(=O)NC(C)c2cccnc2)c1 +CCc1cc(N2CCOC(c3nc(C)cs3)C2)n2ncnc2n1 +COc1ccccc1OCCNC(=O)c1cccc(-n2cnnc2)c1 +Cc1nn(C)c(C)c1C1CCCN1c1nc2ccccc2o1 +CCCNC(=O)C(C)N1CCN(S(=O)(=O)CC)CC1 +COc1ccc(Br)c(NC(=O)NC(C)C)c1 +COC(=O)c1sc(NC(=O)c2cccc(OC)c2F)nc1C +CCc1nc(CNC(=O)c2cnc(C3CCCO3)s2)cs1 +O=C(c1ccccc1F)N1CCN(CCC2OCCO2)CC1 +CCCn1cc(CNc2ccc(CC#N)cc2)cn1 +CCOCC(C)(C)NC(=O)C(c1ccccc1C)N(C)C +Cc1cccc(CC(=O)NCCn2nc(-c3ccccc3)ccc2=O)c1 +COCCOC1CCN(C(=O)c2occc2C)C1Cc1cnn(C)c1 +CCc1cccc(NC(=O)c2c(C)nsc2NC)c1 +Cc1cc(C(=O)NCC(=O)OCc2ccccc2)c(C)n1C(C)C +O=C1CN(C(=O)COC(=O)c2ccccc2)c2ccccc2N1 +Cc1noc(C)c1C1CCCN1Cc1cccc2nonc12 +CNC(=O)CC(NC(C)=O)c1ccc(Br)cc1 +O=C(NCC1(c2cccc(F)c2)CC1)c1cnc(C2CCCO2)s1 +NC(C(=O)NCc1ccco1)c1cc(F)ccc1F +CCCc1noc(CCCC(=O)N2CCCC2(C)C)n1 +O=C(CC1CCCC1)N1CCN(Cc2nc3ccccc3s2)CC1 +CC(=O)c1cccc(-c2c(C)nn(CCC(N)=O)c2C)c1 +CC(C)CCNC(=O)COCc1nc2ccccc2s1 +COCC(=O)NC(C(=O)Nc1cccc(Cl)c1C)C(C)C +COCCC(NC(=O)c1cc2c(C)cc(C)cc2[nH]1)c1ccco1 +CS(=O)(=O)NCc1ccc(Cn2ccccc2=O)cc1 +Cc1ccc(C(=O)NCc2cccnc2Oc2ccc(C)nc2)c(O)c1 +O=C(Nc1cccc(Cl)c1)c1ccc2c(c1)OCCCO2 +O=S(=O)(c1cccc(F)c1)N1CCCC1c1nc2ccccc2[nH]1 +N#CC1CCN(S(=O)(=O)c2ccc3c(c2)CC(=O)N3)CC1 +CC(NCCc1ccncc1)c1cccc(C#N)c1 +COC(=O)CCC(=O)NCCc1ccc2c(c1)OCO2 +O=C(CC(F)(F)F)NCc1ccc(-c2ccn[nH]2)cc1 +CC(C)CN(C(=O)c1cccc(OCC(F)F)n1)C1CC1 +CCCn1ccnc1-c1nccn1CCn1cnnc1 +Cn1cc(C#N)cc1C(=O)Nc1cc(Br)c(=O)n(C)c1 +COc1ccccc1CNc1nc(-c2ccccc2)no1 +O=C(NCC1CC2C=CC1C2)c1cc(=O)[nH]c2ccccc12 +Cc1c(C(=O)OCCn2cc(Br)ccc2=O)cnn1C +Cc1nccn1-c1ccccc1CNC(=O)c1cn[nH]n1 +CC(=O)c1ccc(Oc2cc(C)nc(N3CCOCC3)n2)cc1 +Cn1ccc(NC(=O)c2cc(-c3ccc4c(c3)CCO4)n[nH]2)n1 +COc1ccc(C(=O)CCC(=O)N2CCC(C)CC2)cc1F +CCCCCc1cn(C2c3ccccc3CC2O)nn1 +COc1ncc(Cl)c(N2CCN(c3ccccc3O)CC2)n1 +O=C(CCNc1ncccn1)N1CCc2sccc2C1 +CCn1nnc2cc(C(=O)NCc3sccc3C)ccc21 +O=C(NCc1ccc2ccccc2c1)c1ccco1 +Cc1cc(=O)c(C#N)nn1-c1ccccc1Br +COc1cccc(N2CCN(C(=O)CCOc3ccccc3)CC2)c1 +O=C(NCC1CCCO1)c1ccn(-c2cccc(Cl)c2)n1 +CCCN(CC1CC1)C(=O)Cc1ccc(S(N)(=O)=O)s1 +CS(=O)(=O)c1coc(C(=O)Cc2ccncc2)c1 +Cc1cc(NC(=O)N(C)C2CCCc3ccccc32)no1 +Cn1nc(C2CCN(C(=O)c3cccnc3)CC2)n(C2CC2)c1=O +CS(=O)(=O)NCc1ccc(C(=O)N2CCCCC2)cc1 +CCOc1ccc(NC(=O)NCc2ccncc2)cc1Cl +CC(C)Oc1ccc(C(=O)NC2CCCc3[nH]c(=O)ccc32)cn1 +Cc1csc(N2CCCN(C(=O)NCc3ccccc3C)CC2)n1 +Cc1cc2cc3c(N)nn(CCO)c3nc2cc1C +CC(C(=O)N1CCCCCC1)N1CCn2c(nn(C)c2=O)C1 +C#CCN(CC#C)Cc1cc(OC)c(OC)cc1SC +CCOC(=O)c1nc(C)sc1-c1ccc(OCC)cc1 +Cc1nc(C2CCCN(C(=O)c3cc4c(s3)CCCC4)C2)no1 +Cc1ccccc1C1CC1C(=O)NCCN1CCOCC1 +Nc1cccc(-c2nc(-c3ccccc3Cl)no2)c1 +C=Cn1ccnc1C(O)(c1c(C)noc1N)C(F)(F)F +CC(C)COC(=O)N1CCCN(C(=O)CCn2ccccc2=O)CC1 +CC(=O)c1ccc(NC(=O)c2ccc3ccccc3c2)nc1 +COC(=O)CCCC(=O)Oc1cccc2c1CCCC2 +O=C(C1CCCN1c1nccs1)N1CCCc2ccc(F)cc21 +CCOC(=O)N1CCC(NC(=O)Nc2cc(C)nn2C)CC1 +Cc1nc(CN(C)C(=O)C2CCN(S(C)(=O)=O)CC2)cs1 +Cc1cc(C(=O)Nc2nc3c(s2)CN(C(=O)NC(C)C)CC3)no1 +CC1COCC(C)N1C(=O)Cc1csc(-c2cccs2)n1 +COC(=O)N1CCC(NC(=O)c2cccnc2N(C)C)CC1 +O=C(Nc1cccc2ncccc12)c1cccnc1OCC(F)F +CC(C)C(NC(=O)c1c(F)cccc1F)C(=O)NC1CCCCC1 +Cc1c(C)n(-c2nccs2)c2ncnc(NCc3cccnc3)c12 +Cc1ccc(CCC2CCN(C(=O)c3ccc(=O)n(C)n3)CC2)cc1 +O=C(Nc1cccc(-c2ccn[nH]2)c1)c1ccc(-n2ccnc2)nc1 +COc1ccc(CN(C)C(=O)CCC(=O)c2ccc(C)s2)cc1 +COC(C)(C)c1noc(Cn2ccc(=O)c3ccccc32)n1 +CC(C)OC(=O)CNC(=O)Nc1ccc(Br)cc1Cl +Cc1cc(C(=O)Nc2ccccc2-n2ccnc2)[nH]n1 +COCCN(Cc1nc2sc(C)c(C)c2c(=O)[nH]1)C(C)C(N)=O +CSc1ccc(CN2C(=O)OCC2C(=O)NCC(N)=O)cc1 +COc1ccc(N2CC(C(=O)NCc3ncc(C)o3)CC2=O)cc1 +c1cnc(-n2cc(NCc3cccc4[nH]ccc34)cn2)nc1 +CC(=O)Nc1ccc(CC(=O)OCC(=O)N2CCCC2)cc1 +CC(C)(C)NS(=O)(=O)c1cncc(Br)c1 +CCc1nnc2sc(C34CC5CC(CC(C5)C3)C4)nn12 +Cc1cc(=O)oc(C)c1C(=O)NC(C)CCc1ccccc1 +O=C(c1cccc(Oc2ncccn2)c1)N1CCOCC1 +Cc1ccccc1Cn1nnc(C#N)c1-c1cccnc1 +CCS(=O)(=O)N(Cc1ccccc1)c1ccc(C(C)=O)cc1 +Nc1ccc(F)c2c(Br)cnc(NCCO)c12 +Fc1cccnc1N1CCC(c2nccn2Cc2ccccc2)CC1 +O=S(=O)(NCc1ccncc1)c1cncc(F)c1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1cccc(C#N)c1 +COc1ccc(SCC(=O)c2c(C)nc3ccccn23)cc1 +Cc1ccc(S(=O)(=O)N(C2CC2)C(C)C(C)C)cc1C(N)=O +CC(C)C(NC(=O)C1CSc2ccccc21)c1ccncc1 +Cc1ccc(NC(=O)C(C)Sc2nncn2C)cc1 +CNC(=O)c1cccc(CNC(=O)c2c[nH]c3cc(Cl)ccc23)c1 +COC(=O)c1sccc1S(=O)(=O)NCCc1cccs1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cnccn3)cc12 +CCn1ncc2[nH]c(-c3cc(F)ccc3-n3cccn3)nc21 +Cc1cc(CN(C)C(=O)c2cc(Br)cn2C)no1 +CCCS(=O)(=O)N1CCN(C(=O)c2cccs2)CC1 +COc1ccc(OC(C)C(=O)Nc2ccc(C(C)=O)c(C)c2)cc1 +Cc1ccc(CCC(=O)NC2CCCNC2=O)c(C)c1 +CCC1C(=O)NCCN1Cc1nc(-c2ccc(C(C)C)cc2)no1 +C#CCOc1ccc(CCNC(=O)NCc2ccccn2)cc1 +CC(=O)c1cc(CCNC(=O)OC(C)(C)C)cc(C(F)(F)F)n1 +CC(C)(C)NC(=O)N1CCC(c2nc3c(F)cccc3[nH]2)CC1 +O=C(NCc1ccco1)C1CCCN1C(=O)c1nccn2ccnc12 +COc1ccccc1CNC(=O)CSc1nc(C)c(C)n1C1CC1 +Cc1cccc(OCCNC(=O)c2cc(C)n(C3CC3)c2C)c1 +CNC(=O)c1ccc(N)c(OCC(=O)N2CCCCCC2)c1 +Cc1cc(C(=O)N2CCN(C(=O)c3c(C)oc(C)c3C)CC2)c(C)o1 +Cc1cc(Cl)cc(Br)c1S(N)(=O)=O +COC(=O)C(NC(=O)c1cccc(=O)n1C)C(C)C +Cc1onc(-c2cccc(Cl)c2)c1C(=O)NCCCOC(C)C +Cc1nnsc1C(=O)N1CCC(CNS(C)(=O)=O)CC1 +Cc1noc(-c2ccccc2)c1C(=O)OCC(N)=O +COc1cccc(CC(=O)Nc2ccc(F)c(N)c2)c1 +CC(C)Oc1ccc(-c2cc(C(N)=O)nc(N)n2)cc1 +N#Cc1ccc(-c2cccnc2)nc1SCC(=O)c1ccccc1 +CC(O)CCN(C)C(=O)c1ccc(N2CCCCC2=O)cc1 +Cc1cccc(NCc2nnc3n2CCCCC3)c1C +C=CCN(Cc1ccccc1F)S(=O)(=O)c1cccs1 +CCC(=O)NC1CCCN(C(=O)Nc2cc(F)ccc2OC)C1 +CNC(=O)NCC(=O)N(C)C(C)c1cc2ccccc2o1 +NC(=O)c1ccc(F)c(CNCCc2ccco2)c1 +Cc1nc(NC(=O)c2ccc(-n3ccnc3)nn2)sc1C +O=C(Nc1ccc2c(c1)OCO2)c1cncn1-c1ccccc1 +COC(=O)C1CCCN1CCOc1ccc(OC)cc1 +CCc1ccc(OCC(=O)N2CCNCC2)c(C(C)(C)C)c1 +COCCN(C)C(=O)c1cnc(-c2ccc3c(c2)OCO3)s1 +CC(=O)Nc1ccc2c(c1)CCN2C(=O)c1ccco1 +Cc1cc(N2CCCC(c3cncc(-n4ccnc4C)n3)C2)ncn1 +O=C(Nc1nc2c(s1)CCc1ccccc1-2)C1CC1 +Cc1ccc(CNC(=O)NCc2ccccc2Cn2cccn2)cc1 +COCCN(C)C(=O)CCCc1nc2ccccc2[nH]1 +O=C(c1ccco1)N1CCC2(CC1)Cc1ccccc1C2=O +CCNC(=O)c1ccc(C)c(NC(=O)N(C)C(C)CC)c1 +CCOC(=O)Cc1nc(NC(C)=O)sc1CC +O=C(CNS(=O)(=O)C1=Cc2ccccc2CC1)NCc1ccco1 +COc1ccc(CCC(=O)NCc2cn3cccc(C)c3n2)cc1 +CCN(CC)C(=O)CCC(=O)N(C)c1c(C)noc1C +N#Cc1ccc(NC(=O)COC(=O)C2COc3ccccc3O2)cc1 +CC(=O)c1cc(-c2ccc3c(c2)CCC(=O)N3)n(C)c1C +CCOC(=O)C1=C(C)N=C(c2nc(C)nn2-c2ccccn2)C1C +CC1(C)C(NC(=O)C2CC2c2ccc(F)cc2)C2CCOC21 +Cc1ccccc1OCCN(C)C(=O)COc1ccc(C#N)cc1 +CSc1ncnc(NC(C)c2ccccc2)c1C#N +CC1CN(Cc2nc(-c3ccoc3)no2)CCN1c1nccs1 +O=C(Nc1ccccc1)c1ccc(S(=O)(=O)NC2CC2)cc1 +CCCCC1=C(C(=O)OCC)C(c2ccccn2)NC(=O)N1 +CC(C)(NC(=O)c1cc[nH]n1)c1cccc(Cl)c1 +CCC(NC(=O)c1cscn1)(C(N)=O)C(C)C +Cc1ccc(-n2nnc(-c3ccncc3)c2N)c(O)c1 +Cc1cc(C(=O)N2CCN(CC(C)O)CC2)c(C)s1 +Cc1ncc(C(=O)N(Cc2ccccc2)Cc2nccs2)c(C)n1 +O=C(c1c[nH]nc1-c1ccncc1)N1CCCC(n2cccn2)C1 +CC(C)CNc1nc(-c2cc(F)c(F)c(F)c2)no1 +CC(=O)c1c[nH]c(C(=O)Nc2nc(-c3ccccc3)ns2)c1 +CC(c1ccc(-n2cncn2)cc1)N(C)CCC#N +Cc1ccccc1CC1Oc2ccc(O)cc2N(CCCO)C1=O +CCc1ccc(S(=O)(=O)N(C)c2cccc(N)c2)cc1 +CCS(=O)(=O)c1ccccc1C(=O)NCc1cccc(C(N)=O)c1 +CC1CC1CNC(=O)NCc1nc(-c2ccsc2)no1 +COc1cc(C(=O)Nc2nc3c(C)cccc3s2)on1 +COC(=O)c1cccc(C(=O)N(C)C2CCCC(C)C2)c1 +COC(=O)CN(C(=O)COc1ccccc1C#N)C(C)C +Cc1cc(CN(C)S(N)(=O)=O)cc(C)c1OCC(F)(F)F +O=C(Cc1ccc2c(c1)CCCC2)N1CCOCC1C1CC1 +c1coc(-c2csc(-c3ccc4c(c3)NCCO4)n2)c1 +CC(NC(=O)c1cccc(CC#N)c1)c1ccccc1 +Cc1c(Cl)cccc1-n1ccnc1SCC(=O)NC(C)C +CCC(OC(=O)c1cccs1)C(=O)NCc1ccc2c(c1)OCO2 +Cc1n[nH]c2ncc(C(=O)NC3CCCCC3C)cc12 +CCC1Oc2cccc(N)c2N(CC(=O)OC(C)C)C1=O +Cc1noc(CNC(=O)C2CCN(C(=O)c3cn(C)nn3)CC2)n1 +CN(C)c1ccc(C(=O)N2CCCCC2CCn2cccn2)cn1 +O=C(NCc1ccc(-c2noc(-c3ccccn3)n2)s1)C1CC1 +O=C(Nc1ccc(Br)cc1O)c1ccc[nH]c1=O +CN(Cc1ccc(-c2ccccc2)o1)Cc1nc(-c2cccnc2)no1 +O=C(NCCc1cccnc1)C1CC1c1ccccc1 +CCN(CC)C(=O)C1CC(=O)N(Cc2ccccc2)C1 +O=C(Nc1nncs1)NC1CCCN(c2ncccn2)C1 +Cc1cc(C)n(-c2nc(CCNC(=O)CC(C)(C)C)cs2)n1 +CCCOc1cccc(-c2cnn(C)c(=O)c2CC#N)c1 +O=C(COC(=O)c1ccccc1)NC1CCCc2ccccc21 +Cc1cnc(C(=O)Nc2cccc(-n3cnnc3)c2)cn1 +O=C(COc1ccccc1)Nc1cnn(C2CCOC2)c1 +CN(C)C(=O)c1ccc(C(=O)NC2CCc3cc(F)ccc32)cc1 +COc1ccc(C(C)=O)cc1-c1c(C)nn(C)c1C +CC1(C)C(=O)c2ccc(N)cc2N(CCCC(N)=O)C1=O +Cn1c(N)c(C(=O)COC(=O)CC2CC3CCC2C3)c(=O)n(C)c1=O +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)N1CCc2ccccc21 +O=C(NCC(=O)N1CCCCC1)c1cccc2ccnn12 +CC(=O)c1cc2c(cc1Br)N(C)CCC2 +CC(C)(C)OC(=O)N1CC2CC1C(O)(C(F)(F)F)C2 +CS(=O)(=O)c1ccc(-c2nccn2-c2ccc3c(c2)OCO3)cc1 +Cc1cc(C)n(C)c(=O)c1C(=O)Nc1ccccc1Cl +Cc1cccc(CNC(=O)C(C)N2CCN(c3ccccc3)CC2)c1 +Cc1occc1C(=O)Nc1c(F)c(F)c(F)c(F)c1F +COC(=O)c1cccc(C(=O)N2CCCC(c3ccccc3)CC2)n1 +CC(NC(C)c1cccc2ccccc12)C(=O)N(C)CCC#N +Cc1nnc(-c2ccc(C(=O)NCCc3ccc(F)cc3C)cc2)o1 +CN(C)C(=O)c1ccc2c(c1)CCN2C(=O)C1CC1 +Cc1ccc(OCCCS(=O)(=O)c2ccc(N)cc2)cc1 +Cc1cc(CNC(=O)C(c2ccccc2)n2cnc3ccccc32)on1 +Cc1cccc(CN(CCn2cncn2)Cc2cccc(C)n2)n1 +CCn1nccc1CNc1nnc2cc(C)ccn12 +COCC(C)NC(=O)C1CC(=O)N(c2cc(Cl)ccc2OC)C1 +CCCCOc1cccn(Cc2ccccc2C#N)c1=O +CC(C)CN1CC(C(=O)NCc2cc(C(C)C)no2)CC1=O +CCc1ccccc1CNS(=O)(=O)CCOC +COc1ccc2c(c1)CN(Cc1cnc3cc(C)ccn13)CC2 +Cn1cc(C2c3ccccc3C(=O)N2CC(N)=O)c2ccccc21 +CC(C)CNC(=O)c1nc2c(s1)CN(C)CC2 +COCC1COC(Cn2cncn2)(c2occ3ccccc23)O1 +O=C1CN(C(=O)CSc2nnc(C3CC3)o2)c2ccccc2N1 +CCN(Cc1cccc(F)c1)C(=O)NC1CCN(C(=O)C2CC2)CC1 +CCc1nc(CS(=O)(=O)c2ccccc2)sc1CO +CCOc1ccc(-c2ccnc3nc(SCC)nn23)cc1 +Cc1sc(NC(=O)c2ccnc(F)c2)c(C(N)=O)c1C +CCc1ccc(CNC(=O)CSc2nnnn2C)s1 +Cn1c(Cc2ccccc2)nnc1SCC(=O)c1ccc(C#N)cc1 +Nc1cc2c(c(Cl)c1Cl)OC(c1ccccc1)C(=O)N2 +CC(C)C(=O)Nc1nnc(S(=O)(=O)NCC2CCCO2)s1 +COc1cc(OC)c2cc(C#N)nc(-c3cccnc3)c2c1 +O=C(NCCCn1ncc2ccccc21)C1CCCCC1 +NC(=O)Cc1nc(CCc2ccncc2)n(-c2ccc(F)cc2F)n1 +CN(Cc1ccc(C(F)(F)F)cc1)C(=O)COc1ccc(C#N)cc1 +Cc1ccc2ncc(C(=O)N3CCC(Oc4ccccc4)C3)c(=O)n2c1 +COc1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)c2C)cc1 +CCN(C(=O)Nc1nncs1)C(C)c1cccc(O)c1 +O=C(C1COC2(CCN(c3ncccn3)CC2)C1)N1CCOCC1 +NC(=O)Cn1c(=O)n(-c2ccc(F)cc2)c(=O)c2ccccc21 +c1cc(CNc2ccc3c(c2)CCC3)c2[nH]ncc2c1 +CC(=O)N1CCCC1C(=O)NCCc1nc2ccccc2c(=O)[nH]1 +CCc1ccccc1CNC(=O)Nc1cc(NC(C)=O)ccc1OC +Fc1cccc(N2CCOCC3(CCCN(c4cnccn4)C3)C2)c1 +Cc1ccc(NC(=O)c2ccc(OCC(F)(F)F)nc2)cc1F +CN(C)C(=O)c1cc(NC(=O)c2ccc3c(c2)OCO3)c(=O)n(C)c1 +c1nc(C2CC2)sc1CN1CCOC2(CCCC2)C1 +O=C(Cn1ccc(=O)[nH]c1=O)N(C1CC1)C1CCc2ccccc21 +Cc1ccc(-c2nnc(NC(=O)c3ccn(C(C)C)n3)o2)cc1 +CCCCNC(=O)C1CCN(Cc2nc3ccc(C)cc3[nH]2)CC1 +Cc1ccoc1C(=O)Nc1cccc(S(=O)(=O)NC2CC2)c1C +CCOC(=O)N1CCC(Nc2cc(C)nc3c(C)c(C)nn23)CC1 +CC=CCOC(=O)C(NC(=O)c1ccccc1)C(C)C +COC(=O)c1c(C)[nH]c(C(=O)OCC(=O)N(C)C)c1C +COC(=O)c1cc(NC(=O)Nc2ccccc2)cc(C(=O)OC)c1 +CCOCC(=O)N1CCCn2nnc(Cn3cccc3)c2C1 +CNc1cc(-c2ccc3cn[nH]c3c2)c2cc[nH]c2n1 +CC1CN(C(=O)CCn2cnc3ccccc32)CC1N1CCOCC1 +CC1CCC(NC(=O)c2cn[nH]c2-c2cccc(Cl)c2)CC1 +CC(C)c1ccc(NC(=O)Nc2ccnc(C(=O)N(C)C)c2)cc1 +CCC(CNC(=O)NC1CCCc2occc21)c1ccccc1 +O=C(Cc1csc(Cc2ccccn2)n1)Nc1ccncc1 +COC(=O)CC(C)OC(=O)c1ccc(F)c(F)c1 +COc1ccc2nnc(C(=O)NCc3ccc4c(c3)OCO4)nc2c1 +O=S(=O)(NCCc1ccccn1)c1cc(Cl)ccc1Cl +CCn1nc(C)c(NCC=Cc2ccccc2OC)c1C +O=C(NCCO)c1cnn2c(-c3ccccc3)ccnc12 +O=c1[nH]nc(SCC2CC2(Cl)Cl)n1C1CC1 +N#CCCCOc1cccc(NC(=O)c2c[nH]nc2-c2ccccc2)c1 +CC1CN(C(=O)CNC(=O)c2ccccc2Cl)CC(C)O1 +CC(C)c1nc(C(C)NC(=O)C2(C)CC2(Cl)Cl)cs1 +CC(=O)N1CCN(C(=O)CC(C)C)CC2(CC(=O)N(C)C2)C1 +Cc1ccc2[nH]c(C3CCN(C(=O)c4cnccn4)C3)nc2c1 +O=C(CCc1ccco1)NCc1cccnc1-n1cnc2ccccc21 +CC(C#N)Sc1nnc(-c2ccccc2F)n1C1CC1 +Cc1cc(C)n(C2CCCN(C(=O)c3cc[nH]n3)C2)n1 +CC(C)(C)c1cnc(SCC(=O)Nc2ccccc2O)o1 +Cc1ccc(C)c(C(=O)CSc2nccn2C)c1 +Cc1ccc(-c2noc(CNC(=O)COc3ccccc3)n2)cc1 +Cc1cc(C)n2nc(CC(=O)N3CCC4(CCCCC4)CC3)nc2n1 +CC(O)C(NC(=O)C1CC1)C(=O)NC1CC2CCCc3cccc1c32 +CCc1noc(CC)c1CNC(=O)NC(C)Cc1c(C)nn(C)c1C +Cc1cc(C)n(CC(C)CNC(=O)Nc2cc(C)on2)n1 +Cc1noc(C(C)OC(=O)C2CC2c2ccccc2F)n1 +O=C(Cc1ccsc1)NCCc1cn2ccccc2n1 +CC(OC(=O)c1cnn(C)c1)C(=O)N(C)c1ccccc1 +COC(=O)C1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1 +Cn1nc(C(=O)Nc2ccccc2OCC2CC2)ccc1=O +Cc1cc(C)cc(SCCC(=O)N2CCNCC2)c1 +CSc1ccc(CNC2CCCN(Cc3ccccc3)C2=O)cc1 +Cn1cc(C(N)=O)cc1C(=O)OC1CCc2ccc(F)cc21 +CC1(C)C2CCC1(C)C(NC(=O)c1ccc3c(c1)OCC(=O)N3)C2 +CCc1ccc(-c2ccc(N)c(=O)n2CCCOC)cc1 +CC1CCCCC1NC(=O)c1cc2c([nH]c1=O)CCCC2 +CCC(C)C(=O)NC(CC(=O)OC)c1ccccc1 +O=C(CCc1ccco1)Nc1cc(-n2cnnn2)ccc1F +Cc1cnc(CCNC(=O)c2cc(C)n(C3CCCCC3)c2C)s1 +CCOC(=O)C1CCCC(=O)N1c1ccc(Cl)cc1 +CCc1cccc(C)c1NC(=O)COC(=O)c1ccc2c(c1)OCO2 +Cc1nnc2n1CCN(C(=O)c1cc(C)n(C3CCCCC3)c1C)C2 +O=S(=O)(c1cc(Cl)c(Cl)cc1Cl)n1ccnc1 +O=C1NCC(=O)N2CCN(C(=O)CCc3cccnc3)CC12 +CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccccn3)n[nH]2)CC1 +COc1ccccc1S(=O)(=O)N(C)CC(=O)Nc1cccc(C)n1 +COc1ccc(NS(=O)(=O)c2c(C)n[nH]c2C)cc1OC +Cc1ccc(=O)n(Cc2nc(-c3ccc(S(C)(=O)=O)cc3)no2)n1 +O=C(Nc1ccccc1C(F)(F)F)c1ncn(-c2ccccc2)n1 +C=CCN1C(=O)C(O)(CC(=O)c2ccccc2OC)c2ccccc21 +O=C(OC1CCN(c2ccc(Cl)cn2)CC1)C1CCC1 +Cc1cc(OCCCn2cc(N)cn2)ccc1Cl +Cc1cc(C)nc(SCNC(=O)c2ccccc2)n1 +CCOc1ccccc1NC(=O)c1ccc(Cn2ccnc2)cc1 +Fc1ccc(Nc2nc3nonc3n3nnnc23)cc1 +COc1cc(CCC(=O)N2CCC(C(N)=O)C2)cc(OC)c1 +CN(C)C(=O)c1cccc(CN2CCOCC2c2cccn2C)c1 +COCc1nc2ncnn2c(N)c1-c1ccc(Br)cc1 +CC(OC(=O)c1ccncc1)c1nc2ccccc2n1C(F)F +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(OC(F)F)c(Cl)c1 +CC1CN(Cc2ccccc2)CCN1C(=O)c1ccc(C#N)cc1 +COc1ccc(-c2c(C#N)nnn2-c2ccccc2C)cc1 +O=C(CC1(O)C(=O)Nc2cc(Cl)cc(Cl)c21)c1cccnc1 +NC(=O)c1ccc(C(=O)Nc2ccccc2F)cc1 +CN1C(=O)COCC1C(O)c1ccc(NC(=O)c2cccs2)cc1 +Cc1occc1CN(C)C(=O)NC1CCCc2ccccc21 +CC(NC(N)=O)C(=O)NCCn1cnc2ccccc21 +O=C(NCCC(O)c1ccccc1)C1CCCCC1 +CCC(=O)N1CCCc2ccc(NC(=O)c3ccc(F)c(F)c3)cc21 +CC1CCCC(OCC(=O)NCCc2cnn(C)c2)C1 +Clc1ccc(NCc2nc3n(n2)CCCCC3)cc1 +CCc1nnc(NC(=O)Cc2ccc(OC)c(F)c2)s1 +COCCN(CC(F)(F)F)C(=O)c1cccc(N(C)C)c1 +Cc1ccc(-c2ccc(=O)n(CC(=O)N(C)c3ccccc3)n2)cc1 +CCCNC(=O)Cn1nnc(CO)c1-c1ccccc1Cl +O=C(Cn1cccc(C(F)(F)F)c1=O)NCCCc1nccs1 +CCOc1ccc2[nH]c3nc(SCC(=O)NC4CC4)nnc3c2c1 +CCN(CCC#N)C(=O)CNc1ccc(F)c(Br)c1 +O=C(Nc1ccc(-c2nnco2)cc1)c1cscn1 +Cc1cc(C)c(CNC(=O)CCc2cccnc2)c(C)c1 +O=C(c1ccncc1)N(Cc1ccc2c(c1)OCO2)C1CCCCC1 +COc1ccccc1S(=O)(=O)N1CCCC1c1nc(C2CC2)no1 +O=C(CCC1CCCC1)NCc1cccnc1-n1cncn1 +CCN(C(=O)C1CC(=O)N(CCOC)C1)C(C)C(C)C +Fc1cc(F)cc(-n2cc(Br)cn2)c1 +CC1CN(CC(=O)OC(C)C)c2ccc(F)cc2N1 +Cc1nn(C(C)C)c(C)c1NS(=O)(=O)c1ccc(F)cc1 +CC(C)NC(=O)CCN1CCOC(c2ccc(Cl)c(Cl)c2)C1 +CC(c1ccncc1)N(C)C(=O)Nc1ccccc1Br +COCCC(C)NC(=O)Nc1ccc(F)c(C(F)(F)F)c1 +CC1CC2CCCCC2N1C(=O)c1ccc(N2CCCC2=O)cc1 +O=c1cccnn1CCNS(=O)(=O)c1ccc(C(F)(F)F)cc1 +O=C(CC1CC2CCC1C2)NCCc1ccc(O)cc1 +Cc1ccc(C(=O)NCC(=O)N2CCOCC2(C)C)s1 +COc1ccc(C(=O)COc2cccc(N)c2)c2ccccc12 +Cc1ccc(OCC(=O)Nc2ccc(Cl)cc2N)cc1 +Cc1csc(CCCCNC(=O)c2cc3c([nH]c2=O)CCCC3)n1 +Cc1cc(=O)n(C)cc1NC(=O)c1cccnc1OCC(F)F +O=c1cc(Cn2cncn2)nc2n1CCCN(Cc1cccs1)C2 +COc1ccc(NC(=O)N(C)c2ccccc2)cc1 +O=S(=O)(c1cccc(-c2cn3ccsc3n2)c1)N1CCOCC1 +Cc1[nH]ccc1C(=O)NCC1(CN2CCOCC2)CCCCC1 +COC(=O)c1cccc(CSc2nnc(-c3ccco3)n2C)c1 +CC(CC#N)N1CCN(S(=O)(=O)c2ccccc2)CC1 +CCc1ccc(C(O)CCN2CC(C)OC(C)C2)cc1 +COc1ccccc1C1CCCN1C(=O)C1CCOc2ccccc21 +Cc1nnc(CNC(=O)NCC(F)(F)F)n1C1CC1 +CC(C)n1nccc1C(=O)NCC(C)(C)c1ccncc1 +Cn1nc(C(=O)OCc2nc(-c3ccccc3)no2)c2ccccc21 +Cc1cc(CNC(=O)CNC(=O)C2CC2)c2ccccc2n1 +Cc1c(CNC(=O)C(CC(C)C)NC(N)=O)cnn1C +O=C(Nc1ccc(F)cc1)c1ccnn1-c1ccccc1 +COc1cc2c(cc1OC)CN(C(=O)NCc1csc(C)n1)CC2 +COc1cc(C(=O)N2CCOCC2)cc(OC)c1OC +O=C(CCCN1C(=O)CSc2ncccc21)NCC1CCCO1 +Cc1ccc(N)cc1NC(=O)c1ccc2c(c1)OCCO2 +O=C(NCCn1nc2ccccn2c1=O)c1cc(C2CC2)[nH]n1 +O=C(NCc1ccc(O)cc1)c1ccnc(OCc2ccccc2)c1 +CS(=O)(=O)N1CCOC(CNC(=O)c2c[nH]nn2)C1 +COc1ccnc(NC(=O)C#Cc2ccccc2)c1 +Cc1ccncc1NC(=O)NCC(CO)Cc1ccccn1 +COc1ccc(Br)cc1CN(C)C(=O)c1ccncc1 +CNC(=O)c1cc(C)ccc1NC(=O)C1COc2ccc(F)cc2C1 +CCN1CC(c2ccccc2)Oc2cccc(N)c21 +CCS(=O)(=O)N1CCC(C(=O)N2CCCCC2)CC1 +CN1CCN(C(=O)C2CC(=O)N(c3ccc(Cl)cc3)C2)CC1 +CCC1CCCN(C(=O)Cn2nnc3ccccc3c2=O)C1 +CCn1cc(C(=O)NCc2cccc(OCc3ccccc3)c2)cn1 +Cc1ccc(NC(=O)CCNC(=O)COc2ccccc2)nc1 +Cc1ccc(C(=O)NC(c2ccccc2)c2nccn2C)c(=O)[nH]1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)N(C)CCC(C)C +COCC(NC(=O)c1cc(-c2ccccc2)ccc1Cl)C(N)=O +C=CCCS(=O)(=O)N1CCC(Oc2cccc(C)n2)CC1 +Cc1noc(C)c1C(=O)Nc1sc(C(C)C)cc1C(N)=O +Cc1ccc(C(C)NC(=O)c2ccc(Br)c(F)c2)o1 +CCC(CC1CCCC1)C(=O)NCCNC(C)=O +Cc1nnc(SCC(=O)NC2C3CC4CC(C3)CC2C4)n1N +O=C(COC(=O)C1COc2ccccc2O1)Nc1ccccc1Cl +C#CCNC(=O)NCCOc1ccc(S(C)(=O)=O)cc1 +O=c1oc(-c2ccco2)nn1CCOc1c(Cl)cccc1Cl +CCC(NCCc1ccccn1)c1cccc(Br)c1 +Cc1nccc(N2CCCC(Cc3ccccn3)C2)n1 +CC(=O)NC(C)(C)c1noc(C(=O)Nc2ccccc2)n1 +COc1ccc2ccn(CC(=O)NC3CCCCC3)c(=O)c2c1 +O=C(CSc1ncnc2sccc12)Nc1nccs1 +O=C(Nc1ccccc1)c1c(-n2cnnn2)sc2c1CCC2 +Cc1cccc(C)c1NC(=O)CNS(C)(=O)=O +Cc1noc(CCCNC(=O)C2CCCCC2C(=O)N2CCCC2)n1 +COc1nc(C)ccc1CNC(=O)N(C)Cc1cc(Cl)cn1C +Cc1ccc(CNC(=O)Cc2ccc(OCc3nnnn3C)cc2)o1 +COc1cccc(NC(=O)N2CCN(S(=O)(=O)C3CC3)CC2)c1 +Cc1nc(NC(=O)c2ccc3c(c2)OCCO3)n[nH]1 +CCN(Cc1cn[nH]c1-c1cccc(C)c1)CC(C)C#N +N#CCCCSc1nnc(NC2CCCCC2)s1 +CC(C)c1csc(CN2CCN(Cc3ccccc3CO)CC2)n1 +Nc1c(NCc2ccc(Cl)cc2)ncnc1N1CCOCC1 +Nc1cccc(OCCNC(=O)c2cccc(F)c2)c1 +COc1c(Cl)cc(C(=O)N2CCC3(CC2)OCCO3)cc1Cl +CC(=O)N1CCCC(c2ccnc(Nc3ncccc3C)n2)C1 +COc1ccc(CN(C)C(=O)CSc2ncn[nH]2)cc1 +COc1cccc(CC(=O)N(C)C2(C#N)CCC2)c1 +Cc1cc(NC(=O)Cn2nc(C(F)(F)F)c3c2CCC3)no1 +Cc1cc(C)c(C(=O)NCc2cccc(NC(=O)N(C)C)c2)c(C)c1 +COc1ccc(NC(=O)NC(C)c2ccccc2)cc1NC(C)=O +CCOc1ccc(C2=CCN(C(=O)c3cccn3C)CC2)cc1 +COc1ccc(OC)c(C2CCN(C(=O)c3c(C)noc3C)C2)c1 +COC(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O +O=C(Nc1cn[nH]c1)c1ccnc(OC2CCC2)c1 +Cc1nc(C)c2c(C)c(C(=O)NCc3ccccc3)sc2n1 +Cc1cc(C(=O)Nc2cccc3cnccc23)ccc1F +COc1ccc(C)cc1NC(=O)N(C(C)C)C1CCN(C(C)=O)CC1 +COC(=O)CC(NC(=O)Nc1ccc2c(c1)COC2)c1cccs1 +CCCCc1nc(CN2CC(n3cc(C)cn3)C2)no1 +C=CCn1cccc(C(=O)Nc2ccc(C)cc2)c1=O +Cn1cc(C(=O)Nc2cc(Cl)ccc2F)c(C(F)(F)F)n1 +CC1CC(c2ccsc2)CN1C(=O)C1CCCN(C(=O)C2CC2)C1 +CNC(=O)C1CCN(c2ncnc3[nH]ncc23)CC1 +CCOc1cc(C#N)ccc1OC(=O)c1cc(C)oc1C +CCN(CC)S(=O)(=O)NCc1ccc(C(=O)N(C)C)cc1 +N#Cc1c(-c2ccc(Cl)cc2Cl)noc1N +CCn1cc(NC(C)c2ccc(O)cc2)ccc1=O +Cc1cccc(C(=O)NCC(=O)NCc2c[nH]nc2C)c1 +CCN1CCN(C(=O)C(C)n2nc(C)ccc2=O)CC1 +NC(=O)C1CCN(C(=O)CCc2ncc(-c3ccccc3Cl)o2)C1 +Cc1ccccc1OC(C)C(=O)N1CCN(CCC#N)CC1 +O=C(CCC1CCCC1)NCc1cccc(NC(=O)C2CCCO2)c1 +COCCCNC(=O)Nc1ccc(C(C)N2CCOCC2)cc1 +CC(C)(CNC(=O)N1CCN(c2nccs2)CC1)c1ccncc1 +Cc1ccc(CNC(=O)Nc2cccc(N3CCCC3=O)c2)cc1F +CCCOCC(=O)Nc1cc(C)nn1-c1cccc(C(F)(F)F)c1 +COC(=O)C(NC(=O)c1ccc(NC(=O)C(C)C)cc1)C(C)C +COc1ccc(C(=O)Nc2ccc(O)cc2)cc1Br +COc1ccc(S(=O)(=O)CCc2nnc(-c3ccncc3)o2)cc1 +COc1ccc(C2CCCN2C(=O)Cc2ccc(O)cc2)c(OC)c1 +Cc1csc(C(NC(=O)C2CC2C)C2CC2)n1 +c1ccc(-n2ncc3c(NCc4cc[nH]n4)ncnc32)cc1 +Cn1nnnc1Sc1c(N)cnc2ccc(Br)cc12 +COc1cccc2c(=O)c(C(=O)Nc3ncccc3C)cn(C)c12 +CC1(C)CCCN1C(=O)NCCCOC1CCCC1 +COc1ccccc1-n1nc(NC2=NC(=O)CN2C)cc1N +CNc1snc(C)c1C(=O)OC(C)C(=O)Nc1ccc(F)cc1 +CCn1nc(C)c(NC(=O)c2cccc(Cl)c2)c1C(N)=O +CC(C)CCNC(=O)C1CCCN(c2ncnc3[nH]cnc23)C1 +CCn1cc(C(=O)Nc2ccc(Cl)cc2Cl)cn1 +COc1ccc(C(O)CNC(=O)C(C)(C)C)cc1C +CC(C)c1nc(CN2CCc3cc(S(N)(=O)=O)ccc32)no1 +NC(=O)Nc1cccc(C(=O)N2CCC(Oc3ccccc3)CC2)c1 +COC(=O)N1CCC(NC(=O)Nc2ccc(C(C)C)cc2)CC1 +COc1ccc(-c2oncc2C(=O)NCc2ccco2)cc1 +CC(=O)Oc1cccc(NC(=O)c2cc3ccccc3o2)c1 +CC(C)(C)OC(=O)N1CCC(Sc2ncc(Cl)cn2)C1 +COc1cc(-c2nnc(CO)o2)cc(OC)c1OC +Cc1sc2[nH]c(=O)n(-c3ccc(Cl)cc3)c(=O)c2c1C +O=C(CC1CCc2ccccc21)NCC1(O)CCCCC1 +Cc1ccc2c(c1)N(C(=O)c1nccnc1N)CC(C)O2 +O=C1NC(C(=O)NCc2ccc3c(c2)CCCC3)Cc2ccccc21 +COC(=O)N1CCN(c2cccc(Cl)c2)CC1 +CN(C(=O)C1CCN(C(=O)c2ccoc2)CC1)c1ccccc1 +COc1ccccc1NC(=O)NC1CNc2ccccc2C1 +COc1cc2cc(C(=O)NCc3ccccc3)[nH]c2cc1OC +CCOC(=O)c1c(NC(=O)c2ccc(Cl)cc2)csc1C +O=C(Cn1c(=O)cnc2ccccc21)N1CCOC2CCCC21 +COc1ccccc1CNS(=O)(=O)c1cccnc1 +Cc1cc(NC(=O)c2nc(S(C)(=O)=O)n3ccccc23)n(C)n1 +COc1ccccc1-c1nc(CSc2nnnn2C2CC2)cs1 +O=C(Nc1ccc2c(c1)CCC2)c1ccc(N2CCOC2=O)cc1 +COc1ccccc1C(=O)Nc1cccc(C#N)c1 +CC(=O)NCCCNC(=O)c1cn(C)nc1C(C)(C)C +CCC(C)NC(=O)c1cc2cc3cc(OC)ccc3nc2o1 +COc1ncc(-c2cccc(-c3cc[nH]n3)c2)c(OC)n1 +Cc1ocnc1CNS(=O)(=O)c1cccc(F)c1 +Cn1nnc2c(Nc3ccc(F)c(Cl)c3)ncnc21 +COc1ccccc1CC(=O)N(CCC(N)=O)c1cccc(C)c1 +COC(=O)CSc1nc2ccccc2n1CC(=O)N1CCCC1 +O=S(=O)(c1ccccc1)N1CCN(c2ccc(F)cc2)CC1 +CCCn1c(=O)sc2cc(S(=O)(=O)NC3CCCC3)ccc21 +CCn1c(=O)c(C(=O)N2CCOCC2)nc2ccccc21 +O=C(c1cccc(Cl)c1)N1CCN(C2CC2)CC1c1ccccc1 +CC1=Nc2ncnn2C(=O)C1CCC(=O)Nc1cccc(Cl)c1 +Cc1c(Br)c(C(=O)NC(C)C)nn1C +COc1cc(C)c(C(=O)CNC(=O)c2ccco2)cc1C +CC1c2ccsc2CCN1S(=O)(=O)c1ccc(F)cc1F +CC(C)n1cnc2cc(C(=O)N3CCCC(c4ccn[nH]4)C3)ccc21 +CCNC(=O)c1ccc(NCc2cccs2)c(C)c1 +COc1ccc(CC(=O)Nc2ccc(NC(=O)C(C)C)cc2)cc1 +COCCC1CN(Cc2ccc(OC3CCCC3)cc2)CCO1 +O=C(NCCC(=O)N1CCCc2cc(F)ccc21)c1ccsc1 +c1ccc(C2=Nn3c(nnc3-c3ccccn3)SC2)cc1 +N#Cc1cccc(S(=O)(=O)NCC2Cc3ccccc3O2)c1 +COCC1c2nnn(CC3CC3)c2CCN1C(=O)c1ccoc1C +CCS(=O)(=O)N1CCC2C1CC(=O)N2Cc1ccncc1 +CCN(CC)C(=O)N1CCN(C(=O)c2sccc2OC)CC1 +CC(NC(N)=O)C(=O)NCc1ccc(OCc2cccnc2)cc1 +C=CCNC(=O)c1cc(S(=O)(=O)NC(C)(C)C)ccc1C +CC1CN(C(=O)CCS(=O)(=O)c2ccc(Cl)cc2)CC(C)O1 +CCOC(CC(C(C)C)N1CCOCC1)n1nnc2ccccc21 +CCOC(=O)c1noc(C(=O)NCc2ccccc2F)c1N +CN(Cc1cccc2ncccc12)C(=O)CCc1ccc(=O)[nH]n1 +Cn1nnnc1SCc1ccccc1Br +CCOCCC(=O)NC(C)c1cnn(-c2ccc(F)cc2F)c1C +O=C(Nc1cc(F)cc(F)c1)c1c[nH]c2ccc(F)cc2c1=O +COc1ccc2c(C(=O)CN3CCN(CCO)CC3)c[nH]c2c1 +NC(=O)c1cc(NCc2nc(-c3ccsc3)no2)ccc1Cl +Cc1ccccc1NC(=O)NCCc1ccc(-n2cccn2)cc1 +N#Cc1cc(NC(=O)NCc2ccnc(OC3CCC3)c2)ccc1F +N#Cc1c(F)cccc1NCc1ccccc1CN1CCOCC1 +N#Cc1c(NC(=O)c2cnccn2)sc2c1-c1ccccc1CC2 +CC(C)n1c(=O)n(CC(=O)NC(C)(C)C)c2cccnc21 +c1ccc2c(c1)ncn2Sn1cnc2ccccc21 +CCc1n[nH]c(C2CN(CC(=O)N(C)Cc3ccco3)CCO2)n1 +CCc1nc(CNc2cccc(-c3cccs3)c2)no1 +CN(C)C(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +CC(CNC(=O)N(C)C(C)c1cccnc1)Oc1cccc(F)c1 +N#Cc1ccc(-c2noc(-c3ccc(C#N)cn3)n2)nc1 +CCCn1c(=O)n(CC(=O)N(C)CC(N)=O)c2ccccc21 +Cc1ccc(C(=O)NCCc2ccccc2)cc1F +CCCC(C(=O)N1CCC(c2n[nH]c(=O)n2CC)CC1)n1cccc1 +O=C(c1c(F)cccc1F)N1CCCC1c1nc(C2CC2)no1 +Cc1nc2nc(C(F)(F)F)nn2c(N)c1-c1ccccc1 +Cc1nnc(SCC(=O)NCc2snnc2C)s1 +O=C(NCCNC(=O)c1ccc(O)c(Cl)c1)c1ccc(O)cc1 +O=S(=O)(Nc1cccnc1)c1ccc2c(c1)COC2 +N#Cc1ccc(CN2CCN(C(=O)c3cc4ccccc4o3)CC2)cc1 +COCC(C)OC(=O)c1cn(-c2ccc(C(F)(F)F)cn2)nn1 +NC(=O)C1CCN(C(=O)NCCc2cccs2)CC1 +C=CCn1c(C)cc(C(=O)CSc2ccc(NC(C)=O)cc2)c1C +CCCCCNC(=O)Nc1ccc(NC(=O)C2CCCO2)cc1 +O=C1CCC(C(=O)Nc2cccc(-c3ccc4c(c3)CCO4)c2)N1 +O=C(CCC(=O)c1cccs1)NC1CCCc2ccccc21 +CCOC(=O)c1sc(NC2CCCC2)nc1C +CN(C)c1ccc(Cl)cc1NC(=O)CNc1ccc(C#N)cc1 +Cc1cc(C)nc(Sc2ncnc3sc4c(c23)CCC4)n1 +CCCNC(=O)COCc1cc(-c2cccs2)on1 +Cc1cc(NC(=O)c2c[nH]c3ccccc23)n(C)n1 +OC1COCCN(c2noc(-c3ccccc3)n2)C1 +NC(=O)C1CCCN1c1ccc2nnc(-c3ccccc3)n2n1 +CCCc1nnc(NC(=O)c2cccc3cccnc23)s1 +Cc1cc(C(=O)COC(=O)c2cn[nH]c2C(C)C)c(C)n1C1CC1 +COc1cc[nH]c(=NS(=O)(=O)c2ccc(C)c(C(F)(F)F)c2)c1 +CC1CCN(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)CC1 +Cn1c(CCNC(=O)c2cccnc2)nc2ccccc21 +CCCS(=O)(=O)N1CCC(c2cnn(-c3cccc(C)c3)c2)CC1 +Cc1nn(C)c2c(NCc3ccccn3)nc(C(C)C)nc12 +CC(NC(=O)C1COc2ccccc21)C1CCCCC1 +O=C(COc1ccc(F)cc1)Nc1nccs1 +COc1ccc(OC)c(C(O)CNC(=O)Nc2cc(C)nn2C)c1 +C#CCCNC(=O)NC1CCCOc2c1ccc(Cl)c2Cl +CCCC(=O)Nc1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1 +NC(=O)c1cc2c(nc1-c1ccc(F)cc1Cl)CCC2 +Cc1ccccc1Oc1ccnc(CNC(=O)c2nccn2C)c1 +Cc1ccsc1C(=O)OCC1(C#N)CCOCC1 +CC(C)(C)CC(=O)NCC(=O)Nc1ccc(-c2cnco2)cc1 +CCCCn1c(N)c(N(CC)Cc2nnc(C)o2)c(=O)[nH]c1=O +COc1cc(C)sc1C(=O)OCC1CCCO1 +CCOC(=O)Nc1cccc(OC(=O)c2ccoc2)c1 +O=C(NC(c1ccccc1)C1CC1)C1CCN(C(=O)NC2CC2)CC1 +CCOC(=O)c1ccoc1COC(=O)c1c(C)cc(=O)oc1C +CCCCc1nc2cc(C(=O)N(C)Cc3nc(C)c[nH]3)ccc2o1 +CC(CC1CCCC1)C(=O)NC1CCN(C(=O)c2ccco2)CC1 +CC(C)CC1COCCN1C(=O)c1cnn(CC(C)C)c1C(F)F +Cc1sc2ncc(C(=O)NCCCO)c(=O)n2c1C +Cc1nn(C)c(C)c1CC(=O)OC1CC2CCC1(C)C2(C)C +O=C1COc2nc3cc4c(cc3cc2CN1Cc1ccccc1)OCO4 +Cc1ccc(-n2cnc(-c3cc4ccccc4oc3=O)c2)cc1 +Cc1cc(C)c2c(cnn2CC(=O)N2CCc3ccccc3C2)c1 +NC(=O)c1ccc(S(=O)(=O)Oc2ccccc2F)cc1 +CCOC1COC2(CCCN(C(=O)c3cccc(C)n3)C2)C1 +OC(c1ccccc1)c1cnn(-c2ccccc2)c1 +Cc1nonc1C(=O)N1CCCC(Nc2ccc(F)cc2)C1 +Cc1ccccc1OCCCN(C)C(=O)NCc1ccncc1 +O=C(Cn1ccccc1=O)Nc1ccc(N2CCCC2)nc1 +CCC(=O)NCCNC(=O)c1cc2cccn2cn1 +Cc1c(Cl)cccc1NC(=O)CSc1nnc(-c2ccco2)o1 +c1cc(-c2ncc(CN3CCOCC34CCC4)s2)cs1 +CCC(c1nnnn1C(C)C)N1CCN(c2cccc(C)c2C)CC1 +O=C(CCNC(=O)c1ccsc1)NCc1cc[nH]n1 +CCC1CCCN(C(=O)NCC(C)(C)N2CCOCC2)C1 +Cc1noc(C2COCCN2Cc2nc(-c3cccs3)no2)n1 +COC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccoc2C)cc1 +NC(=O)c1ccc(S(=O)(=O)C2CCCC2)cc1 +CCOC(=O)c1ccc(NC(=O)NC(C)(CO)C2CC2)cc1 +CCOC(=O)C(C)(NS(=O)(=O)c1ccc2c(c1)CCC2)C(C)C +Cc1ccc(C(C)NC(=O)Nc2cnn(CC3CCCO3)c2)cc1 +CC(Cc1ccccc1F)NC(=O)Cn1cnnn1 +O=C(CCSc1ccc(Cl)cc1)Nn1cnnc1 +Cc1nnc(SCC(=O)c2ccc(S(C)(=O)=O)cc2)n1C +COCCNc1nnc(-c2cccn(C(C)C)c2=O)s1 +Cc1nc(C(=O)NCCO)nn1-c1ccc(Cl)cc1 +Cc1cccc(NC(=O)Cn2nc(C(F)(F)F)n(C)c2=O)c1 +COc1ccc(Cl)cc1N1CC(C(=O)Nc2cccnc2)CC1=O +COc1ccc(C(=O)Nc2cc(C)nn2C)c(O)c1 +c1cnc(-n2nc(-c3cccs3)c3c2CCNC3)nc1 +CCc1n[nH]c(SC(C)C(=O)Nc2ccc3c(c2)CCC3)n1 +O=C(NCc1cccnc1)C1CC2OCCC2N(c2ncccn2)C1 +N#Cc1cc(-c2ccccc2)cn2nc(-c3ccc(N)cc3)nc12 +Cc1n[nH]c2ncc(C(=O)NCCCOC(C)c3ccccc3)cc12 +CC1CN(C(=O)NCCc2cnn(C)c2)CC(C)O1 +FC(F)c1nnc(NCc2cnc(C3CC3)s2)s1 +CCCCOc1ccc(C(=O)Nc2ccccc2NC(C)=O)cc1 +O=C(NCc1noc(COc2ccccc2)n1)c1cccc(Cl)c1 +CC1(NCc2ccccc2C(F)(F)F)CCOC1 +CCOC(=O)C(Nc1cccc(F)c1)C1CCOC1 +CCOc1cc(NC(=O)N(CC)CC)ccc1OC +Cc1noc(CCCC(=O)Nc2ccc(Br)cc2O)n1 +CC(Oc1ccncn1)c1cccc2ccccc12 +CNC(=O)NC(C)(C)C(=O)Nc1ccc(OC)c(Cl)c1 +COCCOC(=O)CC1C(=O)NCCN1C(=O)C1CCCC1 +Cc1c(C(=O)Nc2cc(Cl)ccn2)cnn1-c1ccncc1 +CCCc1nnc(SCC(=O)N2CCCC2)n1N +COc1ccc(CCNC(=O)NCC(=O)NC(C)(C)C)cc1 +COc1ccnc(NC(=O)c2ccc(N3CCCC3)c(F)c2)c1 +CCC(C)NC(=O)c1cccc(S(=O)(=O)N(C)C(C)C)c1 +O=C(NCC(C1CCOC1)N1CCOCC1)C1CCCO1 +CCc1ccccc1NC(=O)C1CC(=O)N(C(C)(C)C)C1 +CCNC(=O)N(Cc1ccc(OC)cc1)Cc1ccccn1 +O=C(NCCNC(=O)c1cc(Cl)ccc1Cl)c1cccnc1 +CCC=CCCOC(=O)c1cc(C(N)=O)cs1 +O=C(Nc1ccccc1F)C1CCCN1c1nccs1 +COC(=O)c1cc2c(=O)[nH]c(N3CCCCC3)nc2nc1N +COCc1cc(CN(C)C(=O)CCN2CCCC2=O)n[nH]1 +CC(=O)NCCCSc1nnc(N2CCCC2)s1 +Nc1cccc2c1CN(c1cccc(Cl)c1)C2=O +CCc1ccc(N2CC(C(=O)C(C#N)c3ccccn3)CC2=O)cc1 +O=S(=O)(c1cccc(F)c1)N1CCN(Cc2ccco2)CC1 +Cc1ccc(C(=O)N2CCN(Cc3cccc(F)c3)C(=O)C2)cc1O +CCc1nc2nc(C)c(C(=O)N3CCN(C)CC3)cn2n1 +CCOc1ccc(-c2cc(-c3ccco3)[nH]c(=O)c2C#N)cc1OC +COc1ccc(OC)c(CCC(=O)Oc2ccc(C#N)cc2)c1 +NC(=O)N1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 +Cc1ccc(C(=O)OC(C(N)=O)c2ccccc2)cc1-n1cccc1 +CC(C)(C)c1cnc(CNc2cc(C(N)=O)c(F)cc2F)o1 +Cc1ncc(CNc2ccc(NC(N)=O)cc2)s1 +CCOc1ccc(-c2noc(CNC(C)=O)n2)cc1 +CC(=O)Nc1nc(C(=O)Nc2cc(CC(C)(C)C)n[nH]2)cs1 +CCOC(=O)N1Cc2cc3ccc(OC)cc3nc2C1 +COC(=O)CN(C(C)C)S(=O)(=O)c1ccccc1Cl +CC1Cc2ccccc2N1C(=O)NCc1cc(=O)[nH]c2ccccc12 +CCCCNS(=O)(=O)c1cccc(C#CCCO)c1 +O=S(=O)(NCc1cccnc1)c1ccc(F)cc1 +Cn1c(C(=O)NC(C2CC2)C2CC2)cc2ccccc21 +Cc1cccc(C)c1NC(=O)Cn1nc(C)c2ccccc2c1=O +COc1ccccc1-n1ccc2c(cnc3nc(SC)nn32)c1=O +O=C(c1cc2n(n1)CCCO2)N1CC2CCC(C1)O2 +Cn1cc(NC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cn1 +O=C(NC1C=CC(CO)C1)NC1CCCOc2cc(Cl)ccc21 +CNC(=O)C1CCN(c2nnc(C)c(C)c2C#N)CC1 +O=C(Nc1ccc(S(=O)(=O)N2CCCC2)cc1)c1ccco1 +CCOCc1ccccc1NC(=O)NCC(=O)NC1CCCCC1 +CC(C)C(C)(C#N)NC(=O)CSc1nnc2n1CCCCC2 +Cn1nc(C(=O)Nc2nc(-c3c(F)cccc3F)n[nH]2)ccc1=O +CC(NC(=O)Cc1ccc2c(c1)OCCO2)c1ccccn1 +COc1ccc(CCNC(=O)COc2ccccc2)cc1 +CCN(CC)c1ccc(C(=O)Oc2cccc(C(=O)NC)c2)cn1 +CC(NC(=O)c1ccoc1)C(=O)Nc1ccc2c(c1)COC2 +COc1ccc(N)cc1CNC(=O)c1cccc(C)c1 +Cc1ccc(C(=O)N(C)Cc2ccc(F)cc2F)cc1 +N#Cc1c(-c2cccnc2)cc(-c2ccc3c(c2)OCO3)nc1N +COc1ccc(NC(=O)CCc2ccc3c(c2)CCO3)cn1 +Cc1ccc(C)c2c(C)c(C(=O)N3CC(N4CCOCC4)C3)[nH]c12 +O=C(Nc1ccc(F)cn1)c1cccc(-c2ccoc2)c1 +O=C(Nc1ccc(C(=O)N2CCCC(O)C2)cc1)C1CC1 +COc1ccc(Cl)cc1Cn1nc(C#N)cc1C +N#Cc1ccccc1OCC(=O)N1CCN(c2ncccn2)CC1 +Cc1cc(OCc2nsc(N(C)C)n2)ccc1F +CCNC(=O)CCc1ccc(N2CCOCC2)c(N)c1 +CC(=O)NCCNC(=O)c1cnc2c(c1)c(=O)n(C)c(=O)n2C +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1ccc(C(F)(F)F)cc1 +COc1ccc(C(=O)NC(Cc2ccc(C)cc2)c2ccccn2)nn1 +Cc1cccc(C)c1NC(=O)NC1CCN(c2ccccc2)C1=O +Cc1cc(OC(C)C(=O)N2CCNC(=O)C2)ccc1C(C)C +COc1cccc(C(=O)N2CCN(Cc3noc(C)n3)CC2)c1 +CC(NC(=O)Nc1nccs1)c1ccc(S(C)(=O)=O)cc1 +COc1ccc(NC(=O)c2nc3ccccc3nc2OC)cc1 +CC1CCc2nc(CN3CCOC(c4cccs4)C3)sc2C1 +CC(=O)Nc1cccc(C(C)NC(=O)CC2C=CCC2)c1 +COc1ccc(C2=CCN(C(=O)c3n[nH]c4ccccc34)CC2)cc1 +Nc1ccc(S(=O)NCc2ccc3c(c2)OCO3)cc1 +CC(=O)Nc1cccc(COCCOC(C)C)c1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCC(Cc2ccccc2)C1 +Cc1cccc(C(=O)C(C#N)c2ccc(C(F)(F)F)cn2)c1C +COc1ccc(NC(=O)c2csc(Nc3cccnc3)n2)cc1 +CCOc1ccc(NC(=O)Cc2ccc(C)nc2)cc1Cl +O=C(NCC1CN2CCCCC2CO1)N1CCOCC1 +N#Cc1ccc(Sc2nnc(N3CCCC3)s2)nc1 +CCOC(=O)C(O)c1nnc(-c2cccnc2)n1C +COCC(C)Nc1ncnc2scc(-c3ccccc3)c12 +CCn1c(SCCc2nc(C3CCOC3)no2)nc2ccccc21 +NC(=O)c1nc(C2OC(CO)C(O)C2O)cs1 +CC1(C(=O)Nc2ccncc2)Oc2ccc(Cl)cc2NC1=O +C#Cc1cccc(NC(=O)N(CCCO)C2CCCc3ccccc32)c1 +CCc1ccc(C(=O)N2CCN3C(=O)C(C(C)C)NC(=O)C3C2)cc1 +O=C(NCCc1ccccc1)N1CCC2(CC1)OCCO2 +CCn1nnc2cc(C(=O)N3CC(C)c4ccccc43)ccc21 +CCOCc1ccccc1NCc1nc(CC)no1 +COC(=O)Nc1ccc(S(=O)(=O)Nc2onc(C)c2C)cc1 +CCNC(=O)COc1cccc(NC(=O)c2cccn2C)c1 +COC(=O)c1cccc(CCNC(=O)NC2(C)CCC2)c1 +CC(C)(C)c1cc(NC(=O)COC(=O)c2ccsc2)on1 +O=C(CCCOc1ccccc1)Nc1cccc(-c2cn[nH]c2)c1 +Cc1nn(CC(=O)N2CC(C(N)=O)CCC2C)c(C)c1Cl +CC(NC(=O)c1c(F)cccc1Cl)c1ccco1 +O=C(CC1CCCC1)NCc1cc(-c2ccc3c(c2)OCO3)on1 +CC(NC(=O)C(C)N1CCOC(C)(C)C1)c1cc2ccccc2o1 +Cc1cccc(CCc2nc(-c3ccncc3)no2)c1 +O=C1Nc2ccc(Br)cc2C(=O)N2CCCCC12 +CCC1CCCN(C(=O)CCc2c(C)n[nH]c2C)C1 +COc1cc(O)c2c(=O)c3c(OC)c(OC)ccc3oc2c1 +CC(C)CCNC(=O)Nc1ccc2c(c1)CCN2S(C)(=O)=O +COc1cccc(OC)c1C(=O)N(C)c1ccccc1F +Nc1ccc(F)c2c(NCc3ccc(F)cc3)nccc12 +CC(CNS(=O)(=O)c1cnn(C)c1)Oc1ccccc1 +CC(NC(=O)N(C)Cc1ccccc1)C(=O)N1CCCCC1C +CS(=O)(=O)Nc1cccc(NC(=O)COCC(F)(F)F)c1 +CCOc1ccc(F)c(C(=O)NCc2ncccc2F)c1F +COC(=O)CCN(C)C(=O)c1cccc(Cl)c1Cl +CCOc1ccc(S(=O)(=O)N(C)CCC(F)(F)F)cc1 +Cn1cc(N2CCC(NC(=O)CCSc3ccccn3)C2=O)cn1 +CCCCNC(=O)c1cccc(N2CCCC2=O)c1 +CC(OC(=O)c1cc2c(s1)CCC2)C(=O)Nc1cccc(C#N)c1 +CN(Cc1ccccc1)C(=O)Nc1nnc(CC2CCCC2)s1 +Cc1n[nH]c(C)c1C(=O)N1CCN(c2cccc(Cl)c2)CC1 +CC(O)CNc1ncnc2scc(-c3ccc(Cl)cc3)c12 +Cc1cccc(OCC2CN(C(=O)c3cccc(Cl)c3)CCO2)c1 +COc1ccc(C(O)CNc2cccc(NC(C)=O)c2)cc1C +CCCCS(=O)(=O)NCC(O)c1cc(F)ccc1F +CCn1c(NC(=O)c2cccnc2O)nc2ccccc21 +CCc1ccc(CNC(=O)c2cnc(N3CCCC3)nc2)cc1 +O=C(NCc1cccs1)c1cnn(-c2ccccc2)c1C1CC1 +Cn1c(NCc2cc(-c3ccccc3)no2)c(C#N)c(=O)n(C)c1=O +Cc1ccc(C(=O)NCCCn2ccc3ccccc32)cn1 +O=C(c1csc(COc2cccc(Cl)c2)n1)N1CCOCC1 +O=S(=O)(c1cn[nH]c1)N(Cc1ccccc1)C1CC1 +COc1ccc(NC(=O)CCSc2nc(C)cc(C)n2)cc1 +CCc1noc(CN(C)C(=O)NCCOc2ccc3c(c2)CCC3)n1 +Nc1cc(C(F)(F)F)ccc1SCc1cscn1 +CCOC(=O)c1c[nH]c2c(OC)cc(C)cc2c1=O +Cc1nc(COC(=O)C2COc3ccc(F)cc3C2)c(C)s1 +COc1ccc(OC)c(NC(=O)c2cnc3c(C)csc3c2)c1 +COCCN(C1CC1)S(=O)(=O)c1ccc(O)cc1 +COC(=O)NCC(=O)Nc1cc(C(C)(C)C)nn1C +CN(Cc1ccc(Cl)cc1)C(=O)NC1CCC(O)CC1 +OCC1CCN(c2nc(-c3ccccc3)nc3c2CCC3)CC1O +Cc1oc(-c2ccccc2)nc1CC(=O)N1CCCS1(=O)=O +Cc1cc(Nc2nc3ccccc3[nH]c2=O)n(-c2ccccn2)n1 +CC(C)Cc1noc(CS(=O)(=O)c2ccc3c(c2)OCCO3)n1 +O=C(Cc1ccccc1Cl)N1CCN(CCn2cccn2)CC1 +COc1ccccc1CNC(=O)c1cc2c(C)snc2s1 +Cc1cc(C)nc(C2CCN(Cc3ccncc3)C2)n1 +CC1Cc2ccccc2N1C(=O)c1cn2ccccc2n1 +Cc1ccc(OCC(=O)NC(C)c2ccc(F)cc2)cn1 +CS(=O)(=O)NC1CCN(C(=O)c2cc3c(s2)CCCC3)CC1 +CCNC(=O)c1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1 +CN(C)S(=O)(=O)c1ccccc1NC1CCC1 +CC(C)c1csc(C2CCCN(C(=O)CC3CCCO3)C2)n1 +O=C(Nc1cc(-c2cccs2)nn1CCO)c1ccccc1F +CC(=O)NCCNC(=O)COc1cccc(C(F)(F)F)c1 +CCC(C)C(NC(N)=O)C(=O)Nc1cccc(-n2nc(C)cc2C)c1 +COCCCN(C)C(=O)c1nc2ncc(Br)cn2n1 +CC(C)(C)OC(=O)N1CCCC(Oc2nc3ccccc3o2)C1 +CC(C(N)=O)N1CCN(C(=O)Cn2nnc(-c3ccccc3)n2)CC1 +CCN(CC)C(=O)c1ccc(NC(C)C(=O)NC(C)C)cc1 +N#Cc1ccc(CNC(=O)NCCS(=O)(=O)c2ccccc2)cc1 +O=C(c1ccccc1F)N(CCc1cccs1)Cc1ccoc1 +Cc1csc(CNc2cnn(Cc3ccc(Cl)cc3)c2)n1 +O=C(CN(CCO)c1ccccc1)NCc1cccnc1 +C#CCCN1CCN(C(=O)C2c3ccccc3Oc3ccccc32)CC1 +CCOC(=O)c1c(C)nc(N)nc1-c1ccc(OCC(C)C)cc1 +COc1ccc(C(O)C(C)NC(=O)CNc2ccc(C#N)cc2)cc1 +O=C1N(CCCO)c2ccccc2NC12CCCCCC2 +Cc1ncoc1C(=O)N1CCc2[nH]nc(Cc3ccccc3)c2C1 +Cc1ccc(N2CC(C(=O)Nc3nccs3)CC2=O)cc1C +Cc1cc(N(C)C2CCCCC2)nc(-c2ccncc2)n1 +CCC(O)c1c(-c2ccc3c(c2)OCCO3)nc2cc(C)ccn12 +COc1ccc(Cl)cc1NC(=O)NCc1cccc(C(N)=O)c1 +Cc1nc2c(Br)cc(-c3ccncc3)cc2[nH]1 +O=C(CN1CCN(c2nccs2)CC1)NCc1ccc(F)cc1 +Cc1c(C(=O)Nc2cc(CC(C)C)nn2C)cnn1C +CC1CCN(C(=O)C(C)NC(=O)c2ccc(Cl)cc2)CC1 +CCc1cc(NCc2ccncc2CC)nc(-c2ccncc2)n1 +COc1ccc(OC(=O)c2cc(C(N)=O)cs2)cc1 +O=C(C1CCC1)N1CCC(C(=O)N2CCC2c2ccccc2)CC1 +COCc1ncc(C(=O)NCC2CCCO2)c(N)n1 +CC(C)N(C(=O)c1cccc(CSc2nccn2C)c1)C1CC1 +Cc1cc(NS(=O)(=O)c2ccc(Br)cc2)nn1C +COc1cc(OC)cc(C(=O)NCC2(O)CCCC2)c1 +CCOC(=O)N1CCC(S(=O)(=O)NC(C)c2ccccc2)CC1 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)NC1CCCc2ccccc21 +CC1CN(C(=O)Nc2nnc(CC3CCCC3)s2)CC(C)O1 +Cc1cccc(C(C)C)c1NC(=O)C(C)NC(=O)Nc1ccccc1 +COc1nc(C)c(Br)cc1Br +Cc1ccc2cc3c(nc2n1)CCN(C(=O)c1ccc(F)cc1F)C3 +Cc1cc(NC(=O)COc2ccc(Br)cc2F)no1 +CCN(CC)C(=O)c1c(C)nc(N)nc1-c1ccccc1C +Cn1nnnc1-c1cccc(C(=O)Nc2cccnc2)c1 +Cc1nnc(SCC(=O)c2cc(C)n(C3CC3)c2C)s1 +CCOC(=O)C(n1nnc2ccccc21)n1nnc2ccccc21 +O=C(CN(Cc1cccnc1)CC1CCCO1)N1CCCCC1 +CC(C)C(CNC(=O)c1ccc(=O)[nH]c1)Nc1ccccc1 +CC(c1ccc(F)cc1)N(C)C(=O)CCNC(=O)Nc1ccccc1 +O=C(Nc1nc(-c2ccccc2OC(F)F)cs1)c1cnccn1 +Cn1c(C(F)(F)F)nn(CCNC(=O)c2ccsc2)c1=O +FC(F)(F)Oc1cccc2[nH]c(-c3ccncc3)nc12 +COC(=O)c1ccc(-c2ccc(N3CCOCC3)s2)s1 +CCc1ccc(C(=O)NCC(=O)NC(C)(C)C)cc1 +COc1ccc(OC)c(NC(=O)C2CCCN(C(=O)N(C)C)C2)c1 +c1ccc(CCc2noc(Cn3cccn3)n2)cc1 +CCC(=O)Nc1ccc(Cl)c(NCc2nccn2C(F)F)c1 +Cc1ccc(CCNCc2cnc(C)n2-c2ccccc2)cn1 +COc1ccc(-c2noc(CC(=O)Nc3ccccc3C)n2)cc1 +CN(Cc1cccc(C(N)=O)c1)c1ncnc2c1cnn2C +N#Cc1ccc(NC(=O)c2ccc(NC(=O)c3cccs3)cc2)cc1 +O=C(CCc1nc2ccccc2s1)Nc1ccc(Cl)cn1 +CC(=O)NC(C)C(=O)Nc1cccc(C(=O)NC2CC2)c1 +Cc1cccc(C(=O)N2CCN(CCC(N)=O)CC2)c1 +c1cn(C2CC2)c(Sc2ccc3nnnn3n2)n1 +COc1ccc(NC(=O)CCc2cccnc2)c2cccnc12 +CCNC(=O)c1cccc(NC(=O)CNC(=O)OC)c1 +Cc1ccc2ncc(C(=O)Oc3ccc4c(c3)OCO4)n2c1 +Cn1nnc(-c2ccc(NC(=O)N3CCCC(C(N)=O)C3)cc2)n1 +O=C(COc1ccccc1)Nc1ccc(-n2ccnc2)nc1 +CCn1ncc(-c2ccc(Cl)c(Cl)c2)c(N)c1=O +CC(C)Oc1ccc(CNC(=O)c2cncn2-c2ccccc2)cn1 +COc1ccc(CC(=O)NC2CCCCC2O)cc1 +CC(=O)c1c[nH]c(C(=O)Nc2nc3c(s2)CC(C)CC3)c1 +O=C1C(=O)N(CC2CCCCO2)c2ccc(Cl)cc21 +O=C(Nc1nc(C(F)(F)F)cs1)OCC(F)(F)F +CC(=O)Oc1c(O)c2ccccc2c2ccccc12 +CCCCN(CC)C(=O)c1cc(N)c(OC)c(OC)c1 +O=C(C1CCOC1)N(CCO)Cc1ccc(Cl)c(Cl)c1 +CC(=O)Nc1ccc2c(C(F)(F)F)cc(=O)[nH]c2c1 +CC(C)C(C)N(C1CC1)S(=O)(=O)c1cccc(C(N)=O)c1 +COc1ccc(S(=O)(=O)N2CC(O)(C3CC3)C2)c(C)c1C +Cc1nc2c(nc3c(Cl)cc(Cl)cn32)c(=O)[nH]1 +CC(C)N(Cc1cnc(C2CCC2)s1)C1CCOCC1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccc2c(c1)OCCO2 +CCOC(=O)c1cnn(C)c1C(=O)NC1CCCCC1 +CC(C#N)Cn1cc(Br)cc(Cl)c1=O +COc1ccc(CN2CCNC(=O)C2c2ccccc2)cc1SC +Cn1cc(CN2CCN(Cc3ccccn3)CC2)c(-c2cccnc2)n1 +Cc1nn2cc(CCCOC(=O)c3ccoc3)cnc2c1C +Cc1cc(N2CCOC(c3nccc(N(C)C)n3)C2)ncn1 +C=CCOC(=O)c1c(NC(=O)C2CC2)sc(C)c1C +Cc1cc(C)nc(SCC(=O)N(C2CCCC2)C2CC2)n1 +NC(=O)CCN(C(=O)c1ccoc1)c1ccccc1 +O=C1CCC(NS(=O)(=O)c2csc3ccc(Cl)cc23)CN1 +CC(=O)NCC(=O)Oc1ccc(NC(=O)c2sccc2C)cc1 +Cc1nnc(SCC(=O)Nc2ccccc2O)s1 +CCCCOc1cccc(-c2ccc(C(N)=O)c(N)n2)c1 +COc1ccc(F)cc1S(=O)(=O)NC1CCCC1 +NC(=O)NCCc1ccc(C(=O)OCC2CCCCO2)cc1 +COC(=O)Cn1nc2ccc(S(=O)(=O)N3CCCC3)cn2c1=O +OC(CCN1CCc2ccccc21)c1ccc2c(c1)OCCO2 +O=C(OCCNc1cccnn1)c1cccc(N2CCCC2=O)c1 +O=C(CCNC(=O)C1Cc2cc(F)ccc2O1)NCc1cccnc1 +COCCN(C)C(=O)NCc1ccc(OC)cc1OC +CCOCC(=O)N(Cc1ccccn1)c1ccc(Br)cc1 +COCc1ccccc1NCc1cccc(F)c1F +COc1cccc(C2CN(Cc3sccc3C)CCO2)c1 +COc1cccc(CNC(=O)NCc2ccc(-n3cccn3)nc2)c1 +c1ncc2c(n1)CN(c1ncnc3ccsc13)CC2 +CC1CCCN(C(=O)Cn2c(-c3cscn3)nc3ccccc32)C1 +Cc1cc2sc3nc(=O)n(-c4ccccc4)c(=O)n3c2cc1C +COc1ccc(F)cc1C(O)CCc1nc(C)cs1 +Cc1ccc(NC(=O)c2cc3c(=O)n(C)c(=O)n(C)c3s2)cc1 +COc1cc2cc(C(=O)Nc3ccnn3C(C)C)[nH]c2cc1OC +CC(CNC(=O)N1CCN(c2ccccc2O)CC1)Cn1cccn1 +Cc1cc(C)cc(C2(C(=O)NC(C)CN3CCCC3=O)CC2)c1 +CCn1c(C)nnc1SCCNC(=O)c1cc(C)nc(C)n1 +Cc1cc(C(=O)NC(C)Cc2ccncc2)cc(S(N)(=O)=O)c1C +CC(=O)N1CCC(C2NCCc3cc(F)c(C)cc32)CC1 +Cc1cc(CCNC(=O)C2CC(=O)N(c3ccccc3)C2)on1 +COc1ccc(C(=O)Nc2cccc(F)c2)cc1C +Cc1c(Cl)cccc1S(=O)(=O)N1CCC2(CC1)OCCCO2 +CC(C)NC(=O)COC(=O)C(C)(C)c1cccc(Cl)c1 +CCC(=O)Nc1cccc(NC(=O)N2CCCC(CNC(C)=O)C2)c1 +CC(C)CC1NCCc2cc(Br)cc(F)c21 +CSc1ccc(NC(=O)CCC(=O)c2cccs2)cc1 +CCOC(=O)CN(C)C(=O)Cc1c(F)cccc1Cl +CC1(C)CN(C(=O)NCCCOc2ccccc2)CCO1 +CCCc1nc(NC(=O)N(C)Cc2ncnn2C)sc1CC +COc1ccc(CC(=O)NCCC(=O)N2CCCCC2)cc1OC +Cc1cc(=O)n2ncc(-c3ccc(Br)cc3)c2[nH]1 +CCCS(=O)(=O)N(C)Cc1ccc(OC)cc1Cl +Cc1cc(OCC(=O)NCc2ccco2)cc(C)c1Cl +COc1cccc(OCCNS(=O)(=O)C(C)C)c1 +Cn1ccnc(NC(=O)c2ccccc2OCC2CC2)c1=O +COc1ccc(-c2cn3c4ccccc4nc3n2CCO)cc1 +O=C(c1cccnc1)N1CCC2(CC1)C(=O)NCC2c1ccccc1 +C#Cc1cccc(N(C)C(=O)c2ccc(F)nc2)c1 +O=S(=O)(CCCc1ccccc1)c1ccccn1 +COc1ccc(C(CC(=O)NC2CCCC2)n2cccc2)cc1 +COc1ccc(C(O)C(C)NC(=O)CSc2ccccc2C)cc1 +Cc1cc(C(C)NCC(O)c2c(F)cccc2F)c(C)s1 +Cc1nc(C)c(-c2ccnc(-c3ccc(Cl)cc3)n2)s1 +CCCNC(=O)CN(C)C(=O)C1CC1c1ccco1 +Cc1nc(C2CCN(C(=O)Cc3ccc(F)cc3F)CC2)no1 +CN(C(=O)CCOCC1CCCO1)c1cccc2ncccc12 +CC(Oc1ccccc1)C(=O)Nc1ccc(Cl)cc1N +Cc1ccc(CNC2(Cc3cc(C(C)(C)O)on3)COC2)o1 +CCc1cccc(NC(C)C(=O)c2c(N)n(C)c(=O)n(C)c2=O)c1 +NC(=O)C1CN(CC(=O)N(Cc2ccco2)CC(F)(F)F)CCO1 +CCNC(=O)NCC1CCN(c2cccc(OC)c2)C1 +Cc1cnc(C(=O)N2CCN(Cc3c(C)noc3C)CC2)cn1 +CCC(C)Oc1ccc(NC(=O)N(C)CCN2CCOCC2)cc1 +CC1CCCC(C)N1C(=O)COc1ccc(C(=O)N2CCCC2)cc1 +COc1ccc(F)c(NC(=O)NCC(=O)OC(C)C)c1 +Cc1ccc(-c2nc(-c3ccccn3)cc(N3CCC(=O)CC3)n2)cc1 +COc1ccc(CN(C)C(=O)c2cc(F)cc(F)c2)cc1F +Cc1nn(C)c2ncc(NC(=O)CCCc3cccs3)cc12 +CCC1(CNC(=O)Nc2cnn(CC(=O)NC3CCCC3)c2)CCC1 +CN(Cc1ccnn1C)S(=O)(=O)c1ccc(Br)cc1 +O=C(C1CCN(c2nc3c(F)cccc3s2)CC1)N1CCOCC1 +CC(C)c1nnc(-n2nnc(C#N)c2-c2cccs2)s1 +CC(C)c1noc(CCCC(=O)Nc2ccc(N(C)C)nc2)n1 +CC(=O)Nc1ccc2nc(NC(=O)COc3cccc(C)c3)oc2c1 +CC(CC(=O)Nc1ccc(Br)cc1)C(N)=O +Cc1cc(C2CCCN2S(=O)(=O)c2cc(C)c(C)cc2C)no1 +Cc1cc(CN(C)C(=O)Cn2nc3ccccn3c2=O)no1 +Cc1nnc(SCC(=O)n2c(C)c(C)c3ccccc32)s1 +CCOCCOCc1ccc(OC)c(Br)c1 +Cc1cc(C(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)[nH]n1 +O=C(Nn1cnc2ccccc21)c1cnc(C2CCCO2)s1 +CCC(CO)NC(=O)Nc1ccc(NC(C)=O)cc1C(F)(F)F +O=C(Cc1cccs1)N1CCN(c2ccc3nncn3n2)CC1 +O=C(CCc1nc(-c2cccnc2)no1)OCC1CCCCO1 +Cc1nc(C)c(CNCc2ccc(F)c(Cl)c2)s1 +C=CCNS(=O)(=O)c1ccc2c(c1)NC(=O)C(C)(C)O2 +CCc1nc(CC(=O)OCC2CC2(Cl)Cl)cs1 +CCc1cc(CNC(=O)Nc2ccc3c(ccn3CCOC)c2)[nH]n1 +COC(=O)c1cccc(CCNC(=O)N2CCOCC2C)c1 +Cc1nc2ccccc2n1CCNC(=O)c1cc(C(C)C)[nH]n1 +COc1ccccc1C(C)NC(=O)CCC(=O)c1ccccc1 +CSc1nc2nc(-c3ccc4c(c3)CCC4)ccn2n1 +Cc1ccc(-c2nc(C(N)=O)c(N3CCOCC3)o2)cc1 +Nc1ccc(S(=O)(=O)c2ccc3cn[nH]c3c2)cc1 +CCSc1nnc(NC(=O)c2cccnc2N(C)C)s1 +COc1ccc(Cl)cc1NS(=O)(=O)c1cccc(C(C)=O)c1 +O=C(Nn1cnc2ccccc21)c1ccc(OCC(=O)C2CC2)cc1 +Cc1ccc(C)c(NC(=O)c2cnc3cc(C)nn3c2C)c1 +CCCC(=O)Nn1cnc2scc(-c3ccccc3)c2c1=O +COc1cccc2cc(C(=O)Nc3cc(N4CCCC4)ncn3)oc12 +Cc1nccc(C2CCCCN2Cc2ccccn2)n1 +CC(C)(C)NC(=O)CSc1nnc2n1CCN2c1ccc(F)cc1 +N#Cc1ccc(CCC(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)cc1 +CC(C)(CNC(=O)C1CC1(Cl)Cl)C(N)=O +CC(NS(=O)(=O)c1ccc(OC(F)(F)F)cc1)c1ccncc1 +CC(=O)c1ccc(C(=O)NC(C)c2ccc3c(c2)CCC(=O)N3)s1 +COC(=O)C1CCCN(C(=O)c2cccc(S(C)(=O)=O)c2)C1 +Nc1nc(-c2ccccc2)ccc1C(=O)N1CCCCCC1 +CN(C)C(=O)C(O)c1ccc2c(c1)n(C)c(=O)n2C +COC(=O)c1c(C)[nH]c(C(=O)N(C2CC2)C(C)c2ccccn2)c1C +C=CCNc1nnc(SC2CCCCNC2=O)s1 +Cc1ccc(S(=O)(=O)CC(=O)NC(C)(C)C)cc1 +Nc1cc(F)ccc1N(CCO)C1CCCCC1 +CCCN(CC(F)(F)F)c1c(N)c(C)nn1C +Cc1cc(Br)cc(C)c1NC(=O)c1cccc(N)c1C +COCC(C)CNC(=O)c1ccc(Br)cc1O +O=C(NC1CC(=O)N(Cc2ccccc2)C1)c1ccccc1Cl +O=C(NC1CCOc2ccccc21)c1ccc2ncsc2c1 +O=C(c1ccc(Cl)cc1)N1CCC(n2cccc2)CC1 +Cc1cc(C#N)c(NCc2ccccc2C#N)s1 +CS(=O)(=O)c1cccc(-c2ccc(O)c(C#N)c2)c1 +Cc1cccc(C)c1NC(=O)Cc1nc2ccc(Cl)cc2c(=O)[nH]1 +CC1CN(C)c2ccccc2N(C(=O)c2n[nH]c(=O)c3ccccc23)C1 +Cc1ccc(C)c(NCC(O)Cn2nnnc2-c2ccccc2)c1 +CCOC(C(=O)N(C)CC(N)=O)c1ccccc1 +O=C(C1COc2ccc(F)cc2C1)N1CCOC(c2ccccc2)C1 +CCCc1n[nH]c(C2CN(C3CCOC3=O)CCO2)n1 +CCNC(=O)N1CCN(C(=O)Cc2cccc(F)c2F)CC1 +COc1cc(CCNC(=O)c2cnc(C3CCCO3)s2)ccc1C +Cc1ccccc1C(=O)NCC(O)c1cccc(C(F)(F)F)c1 +CCN(CCO)C(=O)c1cccc(C(F)(F)F)c1 +O=C(NCCCO)Nc1ccc(C(=O)NC2CCCC2)cc1 +CCCC(c1cccs1)N1CCC(=O)CC1C +CCc1cccc(OCc2nn3c(C#N)c(C)nc3s2)c1 +N#CCCCN1C(=O)C(O)(c2c[nH]c3ccccc23)c2ccccc21 +CN(C(=O)c1cc2c(s1)CCC2)c1ccc(C(N)=O)cc1 +COc1cc(N2CCOCC2c2nccc(NCC3CC3)n2)ncn1 +Cc1csc(C2CN(CC3=Cc4ccccc4OC3)CCO2)n1 +Cc1ccnc(Nc2nc(CC(=O)NCc3nc(C)no3)cs2)c1 +COCCOC(=O)NC=Cc1nc2ccccc2c(=O)[nH]1 +CCCOc1ncccc1CNC(=O)Nc1cc(C(N)=O)ccc1C +CC(C)(C)c1ncc(CNC2CCCNC2=O)s1 +COCc1nc(N(C)Cc2cccc3ncccc23)c2cnn(C)c2n1 +CCc1c(C)sc(NC(=O)Nc2ccc(C)cc2)c1C(N)=O +O=C(C1CCOCC1)N1CCc2sccc2C1c1cccs1 +N#CCCOc1ccc(Br)cc1Cl +Cc1cc(C)c(NC(=O)c2ccc(-n3cnnn3)cc2)c(C)c1 +CCCc1cc(C(=O)N(C)Cc2cccc3cnccc23)n(C)n1 +CCC(C)C(C)N(C(=O)c1cc(S(C)(=O)=O)ccc1C)C1CC1 +Cc1cc(=O)[nH]cc1-c1ccc(C(=O)NCc2cccc(F)c2)s1 +O=C(Cn1cnc2ccc(F)cc2c1=O)Nc1ccccc1F +COc1ccc(C(=O)CSc2nnc(C)n2-c2ccccc2)cc1 +COc1ccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)cc1 +CCC(C)(CNC(=O)c1ccc2c(c1)COCO2)C(C)O +CCN(Cc1noc(C2CCC2)n1)C(=O)c1cc(C)oc1C +COc1ccc(S(=O)(=O)Nc2ccc(CCO)cc2)cc1 +COc1ccc(C2NC(c3nccs3)Cc3ccsc32)cc1 +CCCCS(=O)(=O)NCC1(c2ccc(F)cc2)CC1 +N#Cc1ccc(OC(=O)C2CCCN2C(=O)c2ccco2)c(Cl)c1 +COC(=O)Cn1cnc2c3cc(OC)ccc3n(C)c2c1=O +Nc1c(NCc2ccc3c(c2)OCO3)ncnc1N1CCCCC1 +Cc1nn(COc2ccc(C(C)C)cc2)c(C)c1N +NC(=O)c1csc(C(=O)Nc2nnc(CC3CCCC3)s2)c1 +CCCC(=O)Nc1cccc(CNC(=O)N2CCCC(O)C2)c1 +CN(C(=O)CS(=O)(=O)c1ccccc1)C1CCCCC1 +COCCCNC(=O)Cn1cnc(C2CCC2)cc1=O +O=C(CCC1CCCC1)N1CCN(C(=O)Nc2ccccc2)CC1 +Cn1ncc(C(=O)N2CCc3ccccc3C2)c1N +COCCN(Cc1ccccc1)C(=O)c1ccc(=O)n(C)n1 +CN(C)c1cccc(C(=O)Nc2ccc(Cl)cc2C(N)=O)c1 +NC(=O)c1ccc(S(=O)(=O)NCc2cn[nH]c2)cc1 +CN1CC(C(=O)Nc2cnc(-c3ccccc3)nc2)CC1=O +Cc1cccc(NCC(=O)Nc2ccccc2)c1C(N)=O +CC(C)CN1CC(C(=O)Nc2cccnc2)CC1=O +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)Cc1ccc(O)cc1 +O=S(=O)(N1CCCCC1)N1CCN(Cc2ccccn2)CC1 +C#Cc1csc(C(=O)Nc2c(C(C)=O)ccc(OC)c2C)n1 +COc1cc(CC(=O)Nc2c(C)cc(C)nc2C)cc(OC)c1OC +Cn1ccc(CSc2nc(-c3ccccc3)c[nH]2)cc1=O +Cc1ncnc2c1CCN(C(=O)c1cccc(C(F)(F)F)c1)C2 +CC(NC(=O)Nc1ccccc1)c1ccc(C#N)cc1 +Cc1cc(NC(=O)CN(C)C(=O)c2c(C)noc2C)no1 +CC(=O)c1ccc(NC(=O)c2cnc(N3CCCCC3)nc2C)cc1 +N#Cc1c(NC(=O)N(CCO)Cc2ccccc2)sc2c1CCC2 +CCCCn1c(-c2ccc3c(c2)OCCO3)ccc(N)c1=O +c1csc(CN2CCCN(c3cncc(-n4cccn4)n3)CC2)c1 +CCOC(C)c1nccn1CC(=O)N(C(C)C)C(C)C +C=CCc1ccccc1OCC(=O)Nc1ccc(C(C)=O)cc1 +CS(=O)c1ccc(CNCCc2cc(F)cc(F)c2)cc1 +Cn1cc(S(=O)(=O)NCCC(C)(C)C)c(=O)n(C)c1=O +OCCn1c(-c2ccccc2)nc2cc(F)ccc21 +Cc1nnc(SC(C)c2nnc(C(F)(F)F)o2)s1 +O=C(NCC1COc2ccccc2O1)c1cc2ccccc2o1 +CC(=O)NCCN1C(=O)c2ccccc2NC1c1cc(C)oc1C +COCC(=O)N1CCCC2(CC(Oc3ccccn3)CO2)C1 +CNC(=O)Cc1ccccc1NC(=O)CC1C=CCC1 +Cc1csc(CCNC(=O)c2cccc(F)c2N)n1 +Cn1ncc(C(=O)NCc2ccncc2)c1-n1cccc1 +OCc1cn2c(-c3ccc4c(c3)OCCO4)csc2n1 +O=c1ccc(Br)cn1Cc1nnnn1-c1ccccc1 +Cc1noc(C2COCC3CN(c4ncc(F)cn4)CC32)n1 +CCCC(=O)Nc1cnn(Cc2cccc(C(F)(F)F)c2)c1 +Cc1ccc2cccc(C(=O)N(CC3CC3)CC(F)(F)F)c2n1 +CCCNc1ncnc2c(-c3ccc(C)cc3)noc12 +CC(NC(=O)Cn1ccc(C(F)(F)F)n1)c1ccccn1 +C=CCn1c(N)nnc1SCc1c(F)cccc1Cl +COc1ccccc1CC(=O)N1Cc2ccccc2CC1C(N)=O +CCOc1ccnc(N2CCN(C(=O)c3c(C)noc3C)CC2)n1 +CCn1c(SCC(=O)c2ccc[nH]2)nnc1N1CCOCC1 +C=CCNC(=O)CSc1nc2ccc(OC)cc2[nH]1 +Cc1ccc(C(=O)Nc2cc3c4c(c2)CCN4C(=O)CC3)cc1 +c1ccc(Oc2cccc(NCc3noc(C4CC4)n3)c2)cc1 +COc1ccc(OC)c(CSc2nnc3ccccn23)c1 +CCc1nc(N2CCCC2)c2oc3ccccc3c2n1 +CC(C)CCn1cc(C(=O)Nc2nc3ccc(F)cn3n2)nn1 +CCc1c(NCc2ccccc2OC)cnn1CC(C)C +COc1cc(-c2cccc(CN3CCOCC3)c2)ncn1 +COC(=O)CC(C)NC(=O)c1cncn1-c1ccccc1 +Cc1cc(=O)[nH]cc1C(=O)N1CCCC2(CCCCCC2)C1 +Nc1ccc(OCC(=O)OCCc2ccccc2)c(F)c1 +CCCNS(=O)(=O)c1ccc(OC)c(-c2nc(C(C)C)no2)c1 +COc1cc2c(cc1O)OCC(c1cc(OC)c3c(c1O)OCO3)C2 +CC(C)(CO)n1c(Cc2ccccc2)nc2cc(N)ccc21 +Cc1ccc(Cl)cc1NC(=O)Cn1cnc2ccccc21 +N#Cc1nsc(C(=O)Nc2cccc3cccnc23)c1N +Cc1noc(C)c1CC(=O)NCc1ccnc(OCC(F)(F)F)c1 +CCSc1ccccc1NC(=O)N1CCCC(N2CCCC2=O)C1 +CCc1ccc(NCc2ccc(-n3cncn3)cc2)cc1 +CN(C)c1cccc(C(=O)Nc2cnn(CCN3CCOCC3)c2)c1 +COc1ccccc1N1CCN(C(=O)CN(C)c2ccccc2)CC1 +CN(CC(=O)N1CCOCC1)C(=O)C1(c2ccccc2)CC1 +Cc1nc2ccccc2nc1SCC(=O)N1CCCCC1C +CN(C)C(=O)N1CCN(C(=O)c2cnn(C)c2-n2cccc2)CC1 +Cc1cc(C)n(CC(=O)NC(C)(C)CNC(=O)OC(C)(C)C)n1 +COc1ccc(C2CCc3nc(N)nn3C2)cc1Cl +OCCc1nc2ccccc2n1CCOc1ccccc1 +O=S(=O)(NCCc1c(Cl)cccc1Cl)N1CCCCC1 +O=C(Cc1ccc(Br)cc1)NCCc1ccc[nH]1 +COCc1ccccc1NCC(=O)N1CC(=O)Nc2ccccc21 +Cc1ccc2c(c1)CCCN2C(=O)c1ccc(=O)[nH]c1 +Cc1cc(C)n(C2CCN(c3ncnc4c3CCC4)C2)n1 +COc1ccc(Cl)cc1-c1cnn(C)c(=O)c1N +CC(C)Oc1ccc2c(c1)nc(CO)n2Cc1ccccc1 +O=C(CC(C1CC1)C1CC1)N1CCN(C2CCCC2O)CC1 +Cc1[nH]c2ccccc2c1C(=O)Cn1ccc2sccc2c1=O +COC(=O)c1ccc(C(=O)N(C)CC(=O)Nc2ccc(C)cc2)cc1 +COC(=O)c1ccc(C(=O)Nc2ccc(C)cc2OC)s1 +Nc1cc(F)ccc1NC(=O)Nc1ccccc1F +N#CCCS(=O)(=O)c1nnnn1-c1ccccc1 +O=C(c1ccc2[nH]cnc2c1)N1CCN(c2nccs2)CC1 +CCOc1ccc(NC(=O)c2ccccc2-n2cnnn2)cc1F +Nc1c(NC2CCCCC2)ncnc1Oc1cccnc1 +COC(=O)CNC(=O)CSc1n[nH]c(=O)n1C1CC1 +N#Cc1ccc(F)c(CN2CCN(C(=O)CN3CCOCC3)CC2)c1 +CCOC(=O)C1(NC(=O)Cc2cn3ccsc3n2)CCCCC1 +Cc1ccccc1OCC1CCCN(C(=O)CCCc2cn[nH]c2)C1 +CCOC(=O)c1csc(NC(=O)Cc2ccccc2)n1 +COCCCn1ccc2c(cnc3c(C(=O)OC)c(C)nn32)c1=O +CNC(=O)CN(C)S(=O)(=O)c1ccc(C(=O)NC)cc1 +CS(=O)(=O)c1ccccc1S(=O)CCc1ccccc1Cl +COc1ccccc1CC(C)NC(=O)c1ccc(F)c(NC(C)=O)c1 +Cc1nnnn1-c1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1 +COc1ccc(COc2cc(N)ccc2OC)cc1 +CCC(C)NC(=O)Cn1cccc(C(F)(F)F)c1=O +CCc1nc(C)c(C(C)OC(=O)c2ccc(C(=O)OC)s2)s1 +C#Cc1cccc(N(C(=O)c2ccco2)C(C)C)c1 +NC(=O)c1ccccc1OCC#CCNS(=O)(=O)c1ccccc1 +CCOc1c(O)c(C(C)=O)c(OC)c2ccoc12 +O=C(Cc1csc(-c2ccoc2)n1)Nc1nnc(C2CC2)s1 +Cc1nc(N2CCCC2)ncc1C(=O)NCCC1=CCCCC1 +COC(=O)C1(N(C)C(=O)c2ccc(-n3ccnn3)cc2)CCCCC1 +CCN(C(=O)CC(C#N)c1cccc(N(C)C)c1)c1ccccc1 +O=C(CCSc1ccccc1)Nc1nnc(-c2ccsc2)o1 +CCN(C(=O)c1c[nH]c2cccc(F)c12)C(C)c1cccnc1 +O=C(Cc1ccc(O)cc1Cl)N1CCOCC12CCC2 +O=C(NC1CC1)C1CCN(c2cccc(C(F)(F)F)n2)CC1 +CCCN(CC1CC1)C(=O)NCc1cc(=O)[nH]c2ccccc12 +CNC(=O)c1ccc(CNC(=O)c2cnn(C)c2)cc1 +CC(=O)NCCC(=O)Nc1nnc(Cc2ccccc2F)s1 +NC(=O)C1Cc2ccccc2CN1C(=O)Cc1ccc(F)c(F)c1 +O=C(Nc1cccc(F)c1F)c1cccc2[nH]ccc12 +CC(C)NC(=O)C1CCCC(Nc2nc3ccccc3c(=O)[nH]2)C1 +O=C1Nc2ccccc2C1Nc1ccc(Cl)cc1 +O=C(Nc1ccc(Cn2cccn2)cc1)NC1CCCC1 +CCN(CC)C(=O)C1CCCN1c1ncc(C(F)(F)F)cc1Cl +Cc1ccc2[nH]cc(C(=O)NCc3ccc4c(c3)OCO4)c(=O)c2c1 +CCn1ncc(S(=O)(=O)NCC2COc3ccccc3C2)c1C +CCC(=O)NC1CC(=O)N(Cc2cccc3ccccc23)C1 +NC(=O)C1CC(=O)N(CCc2ccccc2F)C1 +Cc1cc(=O)n2nc(CNC(c3ccccc3)C(C)C)sc2n1 +CCn1nc(C)c2c(C(=O)Nc3ccc(C)c(F)c3)cc(C)nc21 +COC(=O)N1CCC(NC(=O)COc2ccccc2)CC1 +O=C(CCc1ccc2c(c1)OCO2)Nc1ccccc1 +O=C(Nc1cccc(N2CCCNC2=O)c1)c1ccc[nH]1 +Cc1cc(N)c2c(Br)cnc(C(N)=O)c2c1 +CCCNC(=O)NCc1cccc(C(=O)NC2CC2)c1 +COc1ccc(CN2CCOC(C)C2C)c(OC)c1 +COC(=O)c1cnc2nc(C)ccc2c1NCc1cccc(OC)c1 +COc1ccc(CCNC(=O)N2CCN(CC(C)O)CC2)cc1 +COc1ccc(Cl)cc1C(O)C(=O)N1CCNCC1 +Cc1ncsc1CCNc1nccc(-c2c(C)nn(C)c2C)n1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1ccccc1 +Cc1cc(C)n(CCNC(=O)C2CN(S(=O)(=O)C3CC3)C2)n1 +C#CCCN1CCN(C(=O)C(C)Sc2ccccn2)CC1 +CCOc1cccc(CN(C)Cc2nc(C)cs2)c1 +CC(O)CN(C)C(=O)CCNC(=O)OC(C)(C)C +CCC(=O)N1CCCC(c2nc(-c3cccc(F)c3)no2)C1 +O=C(NC1CC1c1ccccc1)N1CCN(CC2CCCO2)CC1 +CC(NC(=O)c1ccco1)C(=O)Nc1ccc2c(c1)CC(=O)N2 +COc1cc(OC)cc(C(=O)NCCC(O)C(C)(C)C)c1 +CC(=O)Nc1cc(NCc2nnc(C(C)(C)C)o2)ccc1C +Cc1c(F)cc(C(N)=O)cc1NC(=O)N(C)CC(C)C +COc1ccnc2sc(C(=O)c3ccccc3)c(N)c12 +O=C(Nc1nc(-c2ccccn2)cs1)C1CCC1 +CCCCNC(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1 +COc1ccc2c(c1N)C1(CCCC1)S(=O)(=O)N2C +COC(=O)CCCC(=O)NCC1Cc2cc(F)cc(F)c2O1 +CCNC(=O)Cn1c(CO)cnc1SCc1cccc(C)c1 +O=C(NC1CCC1)C1CC2CN(c3ncccn3)CC1O2 +CC1COCCN1C(=O)c1ccccc1Cc1ccccc1 +CSc1ncccc1C(=O)OCC(=O)Nc1ccc(C(C)=O)cc1 +COc1ccc2c(c1)OCC(CNC(=O)CC(F)(F)F)C2 +COC(=O)c1sccc1N(C(C)=O)c1ccccc1 +CNC(=O)c1ccc(NC(=O)c2nn3ccccc3c2Cl)cc1 +Cn1c(=O)cc(C(=O)N2CCCC(O)(CO)C2)c2ccccc21 +CC(=O)Nc1cc(NCc2noc(C)n2)ccc1F +O=c1c(C(F)(F)F)cccn1Cc1ncc(-c2cccs2)o1 +CC(C)Cc1cc(C(=O)Oc2cccc(C(=O)NC3CC3)c2)[nH]n1 +COc1ccncc1C(=O)Nc1ccc(F)cc1F +CCOC(=O)N1CCN(C(=O)c2cc3cc(C)ccc3nc2C)CC1 +Cc1ccccc1C1CC1C(=O)NCC(=O)OC(C)(C)C +O=C(c1ccccc1)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCCc1c(C#N)nnn1Cc1ccccc1Cl +Cc1ncc(CN(C)C(=O)c2ccc(C(N)=O)nc2)s1 +c1cncc(CSc2ccc(-c3cccnc3)nn2)c1 +Cc1ncc(-c2ccncc2)c(CCNC(=O)C(C)(C)C)n1 +O=C(Nc1ccccc1)C1CCN(c2cnccn2)CC1 +O=C(c1cnc(C2CCCO2)s1)N1CCOc2ncccc21 +CC1CN(C(=O)CCNS(=O)(=O)c2ccc(F)cc2)CC(C)O1 +COc1ccc(Cl)cc1Nc1cc(C#N)ccn1 +Cc1c(C(=O)Nc2ccc(Cl)c(Cl)c2)cnn1C +CC(C)n1c(SCC2CCCCO2)nnc1N(C)C +C=CCNC(=O)c1cc(-c2cccc(Cl)c2)on1 +Cc1nn(C2CCCCC2C#N)c(C)c1Br +C#CCNC(=O)NCCc1ccc(F)c(Br)c1 +COCCn1ccc2cc(NC(=O)N3CC(C)OC(C)C3)ccc21 +Cc1cccc2nc(-c3ccccn3)n(CCc3ccccn3)c12 +CSc1ncccc1C(=O)NCC(O)Cc1ccccc1 +COC(C)(CNC(=O)c1cccc(C#N)c1)c1ccccc1F +Cn1nc(CNC(=O)C2CCCCC2)c2ccccc21 +O=C(Nc1ccccc1N1CCCC1=O)c1cc(Cl)c[nH]1 +COc1ccc(C(=O)Nc2cc(-c3ccco3)no2)cc1OC +COc1ccc(S(=O)(=O)NC(C)C(C)C)c(N)c1 +CCCn1nccc1C(=O)Nc1c(C)cnn1Cc1cccc(F)c1 +COc1ccc(C(CC(=O)N2CCN(C)CC2)c2ccccc2)cc1 +O=C(NCc1ccc(F)cc1)c1noc2c1CSc1ccccc1-2 +CCOC(=O)C1CCN(C(C#N)c2ccc(C)cc2)CC1 +CCC(NC(=O)CNC(=O)c1ccccc1)C(C)C +Cc1ccc(C2NCCc3ccc4c(c32)OCO4)cc1O +Cn1nccc1C(=O)Nc1nc2c(Cl)c(Cl)ccc2s1 +COCc1ccc(C(=O)N2CC=C(c3ccccc3Cl)CC2)o1 +CC(CCNC(=O)Cn1cnnn1)c1ccccc1 +CCC(CC)C(=O)c1ccc(S(=O)(=O)CC)cc1 +O=C(NCc1ccc(-n2cncn2)cc1)Nc1cccc(Cl)c1F +O=C(Nc1cncc(Cl)c1Cl)c1ccco1 +CCOc1ccccc1CN(CC)C(=O)c1ccccc1C#N +O=C(NCC1CCOC1)c1cc(F)c(F)cc1Cl +Cn1ncc2c(NCCNc3ncccn3)ncnc21 +Cc1nn(C)c(C)c1C(NC(=O)NCC1(CO)CC1)C(F)(F)F +NC(=O)COc1ccccc1C(=O)Nc1ccc(F)cc1Cl +CSc1nsc(NC(=O)Nc2ccccc2C)n1 +Cc1ccc(C)c(CC(=O)NCC(=O)N2CCc3ccccc3C2)c1 +COc1cccc(C(=O)NC2CCCN(CC(F)(F)F)C2=O)c1F +Cc1noc(C)c1C(C)NC(=O)N1CC(C)OC(c2ccsc2)C1 +O=C(NCC1(c2cccs2)CCOCC1)c1cccs1 +CCOC(=O)CCC(C)NC(=O)NC1CC(C)(C)Oc2ccccc21 +COCc1cccc(CNC(=O)c2cccnc2N2CCOCC2)c1 +CCc1cc2c(=O)n(C(C)C(=O)OC(C)C)cnc2s1 +CCn1cnnc1C1CCN(C(=O)C2CCc3ccccc32)CC1 +O=S(=O)(C1CC1)N1CC(c2nc(C3CC3)no2)C1 +Cc1oc(C)c(C(=O)NCC(c2cccs2)N2CCOCC2)c1C +CC(=O)N1CCCCC1C(=O)Nc1cc(-c2ncco2)ccc1C +CN(CCO)C(=O)COc1cccc(N(C)C)c1 +CC(O)(CNC(=O)COc1ccccc1C#N)c1ccc(F)cc1 +CC1(C)CCCN1S(=O)(=O)c1ccnc(N)c1 +Cc1ccc(C(C)NC(=O)NCC(O)COc2ccc(F)cc2)o1 +CC(C)c1nnc(NC(=O)N2CCc3sccc3C2)s1 +CN(C)S(=O)(=O)N1CC=C(c2ccccc2Cl)CC1 +CC(C)n1c(CC#N)nc2cc(C(F)(F)F)ccc21 +CCC(C)C(C(=O)NCc1ccccn1)c1ccccc1 +COC(=O)c1ccc(OCC(=O)NC2CCC(C)CC2)cc1 +COCc1cc(CNC(=O)Cn2cnc3ccccc3c2=O)n[nH]1 +CCNC(=O)N(C)CCCOc1ccc(S(C)(=O)=O)cc1 +C=CCOc1ccc(C(=O)Nc2cc(Cl)ccc2C(N)=O)cc1 +Cc1occc1CN(C)C(=O)NCc1nncn1-c1ccccc1 +COc1ccc(C(=O)NCc2ccccc2)cc1C +N#Cc1cc(F)cc(C2NCCc3c2ccc(F)c3O)c1 +Cc1ccccc1C1CC(=O)Nc2c1cnn2C1CCCC1 +COc1ccc(C(=O)NC2CCC(O)CC2)cc1N +NC(=O)c1ccc(-c2nnn(Cc3ccc(C(F)(F)F)cc3)n2)cc1 +COCCC1CCN(C(=O)CN(C)C(=O)c2ccccc2F)CC1 +c1cncc(-c2n[nH]c(SCCn3cccn3)n2)c1 +CS(=O)(=O)c1ccc(OCCNc2nccnc2C#N)cc1 +CC(C)n1c(SCC(N)=O)nnc1-c1ccc(Cl)cc1Cl +CCC(=O)Nc1ccc(Cl)c(NC(=O)c2ccc3c(c2)OCO3)c1 +COc1ccc(COc2ccc(N)cn2)cc1C(C)C +Cc1ccc(NC(=O)CSc2nc(C)c(CCO)c(=O)[nH]2)c(C)c1 +CCOc1cccc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c1 +COc1cccc(C(=O)N2CCc3nc4cccnc4cc3C2)c1 +N#CCC(=O)Nc1ncc(Cc2cc(Cl)ccc2Cl)s1 +Cc1cc(F)ccc1NC(=O)c1nc(C)n(-c2ccc(Cl)cc2)n1 +O=S(=O)(NC1CCC(O)CC1)c1ccc(Cl)cc1F +OCc1nc2ccccc2n1CC(O)c1ccccc1 +CC(C)NC(=O)Cc1ccc(NC(=O)c2cc3n(n2)CCCO3)cc1 +C=CCNC(=O)Nc1cccc(N2CCCC2=O)c1 +COCC(NC(=O)CCn1c(C)cc(C)nc1=O)c1ccnn1C +COCC(=O)N1CCN(C(=O)c2nn(C)c(=O)c3ccccc23)CC1 +C=CCc1ccc(OC(=O)c2ccc(-n3cncn3)cc2)c(OC)c1 +Cc1cccc2nc(-c3cccnc3)c(C(C)C#N)n12 +CC(=O)Nc1cccc(CNC(=O)c2ccc(CNC(N)=O)cc2)c1 +N#Cc1ccc(OCC(=O)OCc2nc3ccccc3c(=O)[nH]2)cc1 +CCOC(=O)c1nn(CCO)c2c1CN(Cc1ccc(O)cc1)CC2 +CCCCN(Cc1ccco1)C(=O)C1CCCO1 +Nc1nc(C2CC2)ncc1C(=O)NCc1ccc(Cl)cc1 +CC(C)(C)NS(=O)(=O)c1ccc(C(=O)NCc2ccco2)cc1 +CC(=O)Nc1nc2cc(NC(=O)c3ccccn3)ccc2s1 +CCOC(=O)N1CCN(C(=O)C(CC)n2cccn2)CC1 +CN(C(=O)C1CCOc2ccccc21)c1ccc(Br)cn1 +COCC(=O)N1CCCN(c2nc3c(s2)c(C)nn3C)CC1 +Cc1ccc(-c2n[nH]c(C3CCCCC3)n2)cc1N +O=c1n(CCOc2ccccc2C(F)(F)F)nc2ccccn12 +O=C(NCC1CC2(CO1)CN(c1nncs1)C2)C1CCC1 +CCn1c(CNC(=O)Nc2cccc(C(C)=O)c2)nnc1SC +C=CCNC(=O)Nc1cccc(-c2nccs2)c1 +COC(C)(C)c1noc(-c2cccc(Cn3nc(C)cc3C)c2)n1 +Cc1cc(C(=O)NC2CCCC2)ccc1NC(=O)C1CCC(=O)N1 +CCc1cc(C(=O)N2CCC(Oc3ccccc3F)CC2)n(C)n1 +CSc1nc2nc(C)c3c(=O)n(-c4ncn[nH]4)ccc3n2n1 +CCOC(=O)C1(Cc2ccccc2)CCCN(S(C)(=O)=O)C1 +COc1ccc(CN(C)C(=O)c2ccc3c(c2)CCC3)cc1F +CCc1noc(CC)c1CC(=O)N1CCc2c(F)ccc(F)c2C1 +COc1ccc(NC(=O)c2cc(C(C)C)on2)cc1 +CC(C)CS(=O)(=O)c1ccc(C2(O)CN(CCO)CCO2)cc1 +COCCN(CCOC)C(=O)c1cc(N)n(C)n1 +Cc1csc(CNC(=O)Nc2ccc(C)c(OCC(F)F)c2)n1 +COc1cccc(CC2(c3cccs3)NC(N)=NC2=O)c1 +COc1ccc(C(=O)CSc2nccn2C)cc1OC +COc1ccccc1C(=O)N(C)Cc1ncc(C)c(OC)c1C +COc1ccc(OCc2n[nH]c(-c3cccnc3)n2)cc1 +COCc1cc(C)nc2c1C1=NC=NC(=O)C1S2 +Cc1nn(CCNC(=O)Cn2nnnc2N)c(C)c1Cl +COc1ccc(-n2ccc(C)c(C#N)c2=O)cc1OC +COc1cc(C#N)ccc1OC(=O)CCn1cnc2ccccc2c1=O +Cc1cnc(NC(=O)c2ccccc2S(C)(=O)=O)s1 +COc1ccc(C(=O)N(Cc2ccc(F)cc2)Cc2ccco2)cc1 +Cc1noc(C)c1CCC(=O)Nc1nnc(-c2ccsc2)o1 +CC(C)(C)OC1CCN(Cc2ncccc2C(F)(F)F)CC1 +CC(C)(C)C(=O)NCCCC(=O)NCc1ccncc1 +CCN1C(=O)CCc2cc(NC(=O)OCc3ccccc3)ccc21 +CN(Cc1nccn1C(F)F)C(=O)Nc1cccc2c1OCCO2 +O=C(CSc1nnc(-c2ccccn2)o1)Nn1cn[nH]c1=O +N#Cc1ccc(C(=O)Nc2ccc(-c3nccs3)cc2)cc1 +Nc1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1F +Cn1cc(C(N)=O)c(NC(=O)c2ccc(Cl)cn2)n1 +Cc1ncncc1C(=O)NC1CCCCC1OCc1ccccc1 +COc1ccc(N)cc1NC(=O)COc1ccccc1C +Cn1cc(C(OC(=O)c2nccc3ccccc23)C(F)(F)F)cn1 +Cc1c(CN2CCOC(c3cccs3)C2)cc(C#N)n1C +O=C(NCc1cccc(F)c1)NC1CCN(c2ccccc2)C1=O +COc1ccc(SCCC(=O)Nc2cnn(C)c2)cc1OC +Fc1ccc(C2(CNCc3cccnc3)CC2)cc1 +Cc1cc(C(=O)NCc2ccnc(OC(C)(C)C)c2)ncn1 +c1cnc(-n2cc(NCc3c[nH]nc3-c3cccnc3)cn2)nc1 +COc1cc(C#N)ccc1OCC(=O)NC12CC3CC(CC(C3)C1)C2 +CC(C)c1ccc(C(=O)CSc2nc(N)cc(=O)[nH]2)cc1 +COc1ccccc1OCC(=O)N1CCN(c2ccc(F)cc2)CC1 +COc1cc(NC(=O)CCCO)c(OC)cc1Cl +CC1Cc2ccccc2N1C(=O)c1ccc(N2CCOCC2)cc1 +O=C(C1CCCO1)N1CCCN(c2ccc(C(F)(F)F)cn2)CC1 +COCCCn1c(C(C)(C)C)ccc(C(C)=O)c1=O +CC=CCn1c(N(C)C)nc2c1c(=O)[nH]c(=O)n2C +CC(c1cc(F)ccc1F)N(C)C(=O)c1ccnc(OC2CCC2)c1 +CCc1cc2c(N(CCO)CCO)ncnc2s1 +CCCN(Cc1c[nH]nc1-c1cccs1)CC(F)F +N#Cc1ccccc1OS(=O)(=O)c1cc(F)ccc1Cl +Cc1ccc(CN(C)C(=O)Cn2cc(Cl)cn2)o1 +COc1c(F)ccc2c1C(c1nccs1)NCC2 +O=c1[nH]ccnc1N1CCN(Cc2ccc(Cl)c(F)c2)CC1 +Cc1nc(-c2ccsc2)sc1C(=O)NCc1csc(=O)[nH]1 +CC(C)N(C)S(=O)(=O)c1ccc2c(c1)CCN2 +Cc1cccc(C(=O)NCCc2csc(-n3nc(C)cc3C)n2)c1 +CCN(CCO)C(=O)c1cnc(SC)n1-c1ccc(F)cc1 +CC(c1ccon1)N(C)C(=O)COc1ccc(Cl)cc1Cl +Cc1ccc(NC(=O)CNS(=O)(=O)c2cnn(C)c2)c(Cl)c1 +O=C(c1n[nH]c2c1CCC2)N1CCCC1Cn1cccn1 +COC(=O)c1sc(NC(=O)CCc2cc(Cl)cs2)nc1C +CC(C)N(C)C(=O)CCCc1nnc(-c2ccccc2)o1 +CCn1cnnc1CNC(=O)c1ccc(=O)n(-c2ccccc2)n1 +CCc1c(C(=O)Nc2ccccc2C(=O)C(C)C)[nH]c(C)c1C(C)=O +CCn1nc(C)c(CNC(=O)c2c(Cl)c(C)nn2CC)c1C +CC(C)c1nc2c(NC(=O)c3cccc(Cl)c3)cccn2n1 +c1cnc(N2CCC(OCC3CC3)C2Cc2ccncc2)nc1 +Cc1cc2sc(NC(=O)NCc3nncn3C3CC3)nc2s1 +Cc1ccn(-c2ccc(N3CCCC(C(=O)NCC4CC4)C3)nn2)n1 +CCCn1cc(NC(=O)C(C(C)C)N2CC(C)OC(C)C2)ccc1=O +O=C(NCCOc1ccc(Br)cc1)NCC1CC1 +COC(CNC(=O)c1cc(C)on1)c1ccccc1C +CCc1nnc(NC(=O)CSc2ccc(F)c(F)c2)s1 +CC(=O)NCCNC(=O)N1CCN(CC(N)=O)CC1 +CC(=O)Nc1cccc(OC(C)=O)c1NC(C)=O +Cc1cnc(N2CCOC3(COCCN(S(C)(=O)=O)C3)C2)nc1 +N#Cc1c(Br)ccc(Br)c1F +Cc1cc(C(=O)N2CCN(C)CC2)c(C)n1C1CC1 +CCC1c2ccccc2CCN1C(=O)c1cc(NC(C)=O)ccc1F +CC(=O)Nc1cccc(NC(=O)c2csc(C)c2C)c1 +O=C(NCCOc1ccccc1C(F)(F)F)NC1CCC(O)CC1 +Cn1c(C(=O)N2CCOCC2)ccc1-c1ccccc1Br +CN(CC(F)F)C(=O)C1COc2ccc(F)cc2C1 +COc1cccc(Cn2ccnc2C2CCOC(C)(C)C2)c1OC +CC(C)(C)C(=O)Nc1nc(-c2cccs2)cs1 +CSc1ccc(C)c(C(=O)NCC(=O)N(C)C)c1 +Cc1ccc(SCC(=O)Nc2ccccc2C(=O)NC(C)C)cc1 +C#CCN(CC#C)C(=O)c1cn(-c2ccc(Br)cc2)cn1 +CCC(CO)NC(=O)Nc1cc(-c2ccccc2C)nn1C +Cc1cc(=O)oc(C)c1C(=O)OCC(=O)N1CCOC2CCCCC21 +CNS(=O)(=O)CCCSc1nnnn1C +Cc1noc(C2CCN(C(=O)c3oc4ccccc4c3C)CC2)n1 +c1ccc(COC2COCCN(C3CCOCC3)C2)cc1 +CCOC(=O)c1cnn(-c2ccc(Br)cc2)c1O +CCn1c(SCC(O)c2cccc(F)c2)nnc1-c1ccco1 +Cc1cc(C)cc(CCC(=O)NCc2cnc(C)cn2)c1 +O=C(CCc1cccs1)N1CCCN(C(=O)CC2CCCC2)CC1 +COc1ccc(CNC(=O)NC(Cc2ccccc2)C2CC2)cc1O +O=S(=O)(Nc1ncc(Cl)cc1Cl)c1ccccc1 +O=C(CC1CCCC1)Nc1cc(N2CCOCC2)ncn1 +Cc1nc(SCC(=O)NC(C)(C)C)c2ccccc2n1 +Cc1ccc(C)n1CCN1CCN(C(=O)CC#N)CC1 +CCOc1ccccc1-c1nc(C(=O)NCc2ccncc2)cs1 +COc1cccc2c1OCC(=O)N(c1ccc(Cl)cc1)C2 +CCc1nnsc1C(=O)NC(C)C(=O)NC(C)(C)C +O=C(Nc1sc2c(c1CN1CCOCC1)CCCC2)c1ccco1 +O=C1c2ccccc2NC(C2CC2)N1Cc1ccc2c(c1)OCO2 +O=S(=O)(NC1CC1)c1ccc(-c2cnc(C3CCCC3)o2)s1 +CCOc1cccc(NC(=O)N2CCN(Cc3ccccc3)CC2)c1 +CCOc1c(Cl)cccc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +COc1ccc(OC)c(CC(=O)Nc2ccccc2N2CCCC2)c1 +CCNC(=O)CNc1cccc(NC(=O)c2ccco2)c1 +CC(C)(C)NC(=O)CNC(=O)Nc1ccc(CN2CCCC2=O)cc1 +CCN(CC)S(=O)(=O)CC(=O)Nc1ccc2oc(=O)ccc2c1 +CCN(CCC#N)C(=O)Cc1cccc(OCC#N)c1 +O=C(Nc1ccc(Cl)cc1)N1CCN(C(=O)C2CCCO2)CC1 +CC(C)C(=O)Nc1ccc(CNC(=O)NC2CCC(O)CC2)cc1 +CCc1nnc(-c2cc(S(=O)(=O)NC3CCCCCC3)c[nH]2)o1 +CCN(CC)C(=O)c1n[nH]c2c1CN(C(=O)OC(C)(C)C)CC2 +COc1cccc(NC(=O)N2CCc3ncccc3C2)c1 +Cc1cc(F)ccc1S(=O)(=O)NCc1cscn1 +CC(C)(C)N1C(=O)c2ccccc2C1(O)c1ccccn1 +CC(CNC(=O)c1cc2ccccc2oc1=O)N1CCc2ccccc21 +Cc1nc(N2CCOCC2)nc2c1CCN(C(=O)N(C)C)CC2 +CC1CN(C(=O)CCn2c(C(F)F)cc3cccnc32)CC(C)O1 +Cc1cc(NC(=O)CN(C)C(=O)c2cccs2)c2ncccc2c1 +Cc1cc(=O)c(O)c(CN(C)CCc2ccncc2)n1C(C)C +Cc1cccnc1NC(=O)c1ccn(COc2ccc(F)cc2)n1 +CC(C)(C)OC(=O)N1CCc2c(N)ncnc2C1 +N#CC1(C(=O)N2CCCC2C2CCCC2)CCCC1 +CCCc1nc(N2Cc3cnn(CCO)c3C2)c2cnn(C)c2n1 +COC(=O)c1ccc(NC(=O)C(O)c2ccccc2)cc1 +COCCOc1c(Cl)cc(Cl)cc1CO +Cc1cc(C(=O)Nc2cc(-c3cccs3)nn2CCO)c(C)o1 +Cc1ccc(NC(=O)NCCc2ccccc2)cc1N1CCCC1=O +Cc1nn(-c2ccccn2)c(C)c1N1CCN(C(=O)C(C)C)CC1 +CC(C)c1nc2cc3c(cc2n1CCC#N)OCCO3 +Cc1ccc(C)c2c(C)c(-c3nc(CN4CCOCC4)no3)[nH]c12 +O=C(Nc1ncnc2nc[nH]c12)C12CC3CC(CC(C3)C1)C2 +CCOCc1ccccc1NC(=O)NCc1ccccc1OC +CSc1ccc(Cl)c(C(=O)NCc2nnc3n2CCC3)c1 +COc1ncccc1Cn1c(C)cc(=O)c2ccccc21 +COCCOC1CCN(C(=O)Nc2cc(OC)ccc2F)CC1 +COc1ccc(NC(=O)CSc2nncn2CC(F)(F)F)cc1 +Cc1ccc(OCC(=O)Nc2ccccc2-n2cnnn2)c(C)c1 +COc1cc(N)ccc1OCc1ccc(F)cc1Br +O=C(NC1CC(=O)N(Cc2ccccc2)C1)c1ccco1 +Cc1nc(C)c(C#N)c(SCC(=O)Nc2nccs2)n1 +COc1ccnc(NC(=O)C2CCCc3sccc32)c1 +CCCOc1cccc(CNC(=O)Cn2c(C)c(C)sc2=O)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)NC(C)(C)C +O=C(Cn1ncc(=O)c2ccccc21)Nc1cccc(Cl)c1 +Cc1ccc(C)n1CCOc1cccc2cccnc12 +CC(CNC(=O)c1ccn2cncc2c1)Nc1ccccc1 +CCc1cccc2c(CCNC(=O)C3CCC3)c[nH]c12 +C=CCOc1ccc(OCC(=O)Nc2cc(C)nn2C)cc1 +C=CCNC(=O)NCc1ccc(C(=O)NC2CC2)cc1 +O=S(=O)(Nc1cccc(F)c1)c1ccc(F)cc1 +CC(C)C1Nc2ccccc2C(=O)N1CCc1ccccc1 +CN(CC(=O)NC(C)(C)C)C(=O)c1cc(Cl)ccc1Cl +CC(C)COc1ncc(CNCc2cnnn2C)cc1Cl +O=C(NCCCN1CCCCCC1=O)c1ncoc1-c1ccccc1 +COc1ccc(C(=O)CCCC(=O)N=c2[nH]c3ccccc3[nH]2)cc1 +CNc1nc(-c2cc3c(nc2C)CCCC3)cs1 +Cc1ccc(N)c(C)c1NC(=O)c1ccccc1F +CC(C)C(NC(=O)c1cncc2cnccc12)C(=O)N1CCCC1 +CC(=O)Nc1ccc(C)cc1NC(=O)C1CC=CC1 +Cc1scc2nc(C(=O)NCc3ccc(F)cc3)nc(N(C)C)c12 +O=C(NC(CO)c1ccccc1)NC1CCSc2c(F)cccc21 +Cc1ccc(NC(=O)N2CCN(CCn3cncn3)CC2)cc1C#N +CCc1cnc(C)nc1NCc1ccccc1CN1CCCC1=O +CCOC(=O)CNC(=O)C(C)NC(=O)c1ccco1 +Cc1ccc2nc(CNC(=O)c3ccc4ccccc4n3)[nH]c2c1 +CC(C)n1ncc2cc(C(=O)Nc3nccs3)c(N)nc21 +COCCc1noc(CSc2cccc3cccnc23)n1 +CC1NCCc2c1sc1nc(Cc3ccccc3)nn21 +O=C(NCCc1nc2ccccc2s1)C1CC2COCC(C1)C2=O +COc1ccc(Cc2nc3ccc(N)cc3o2)cc1 +CC(NS(=O)(=O)c1ccccc1)C(=O)NC(C)c1ccncc1 +CC1CCN(c2ncc3c(n2)CN(CCc2ccccc2)C3=O)CC1 +Cc1ccccc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +CCc1nnc(C2CCN(C(=O)COc3ccccc3)CC2)s1 +CCCn1cc(C(=O)N2CC(Oc3ccccc3OC)C2)c(C)n1 +Cc1noc(C)c1CC(=O)NCC(C)c1cccs1 +CCc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)n1CCO +Nc1cc(N)nc(SCC(=O)NC2CCCc3ccccc32)n1 +CCc1cc(OC)c(OC)cc1C(=O)Nc1ccc(OC)cc1 +CCCn1nccc1NC(=O)c1ccc(F)c(C(F)(F)F)c1 +CC(=O)c1ccc(OC(=O)C2CCN(c3ncccn3)CC2)cc1 +Cc1cc(C)c(C(=O)N(C)c2cccc3ncccc23)o1 +COCc1nc2cc(C)cnc2n1Cc1ccccc1C#N +CC(=O)c1csc(C(=O)NCc2nnc(C3CC3)n2C2CC2)c1 +O=C(NCc1ccco1)C1C2C=CC3(CN(C4CCCC4)C(=O)C13)O2 +COc1ccc(OC)c(C(=O)NCC(=O)Nc2cccc(F)c2)c1 +CCC(C)NC(=O)Cn1c(=O)sc2ccccc21 +O=C(NCc1ccnc(OCc2ccc3c(c2)OCO3)c1)N1CCC1 +Cc1cc(C(=O)N(Cc2ccco2)Cc2ccco2)c(C)n1C1CC1 +CC(CC(=O)Nc1ccc(Cl)cc1F)n1ccnc1 +COc1ccc(CNC(=O)c2cc(Cl)c3c(c2)OCCO3)cc1 +CC(NC(=O)c1cncc(Br)c1)C(C)(C)C +CC(c1cccc(Cl)c1)N(C)C(=O)c1cnn(-c2ccccc2)c1 +CC(CC(=O)N1CCC(c2nnc3n2CCC3)CC1)C1CC1 +CCNc1nnc(SCc2csc(C3CCCC3)n2)s1 +CC1c2cccn2CCN1C(=O)c1cn2ccsc2n1 +Cc1nc(-c2cccnc2)nc(N2CCNC(=O)CC2)c1C +NC(=O)C1CCN(S(=O)(=O)c2ccccc2N)CC1 +CCOCC1CCCN(C(=O)C2CCCCN2C(=O)c2ccco2)C1 +O=C(NCc1ccno1)c1ccn(-c2ccc(F)cc2)n1 +CN(Cc1cccc(C#N)c1)C(=O)NCCN1CCOCC1 +CCCNC(=O)CCNS(=O)(=O)c1ccc2ccccc2c1 +CCNC(=O)C1Cc2ccccc2CN1C(=O)c1ccccc1Cl +O=C(CCc1cccc(Cl)c1)N(CCO)Cc1ccccc1 +O=c1cc(-c2ccccc2)nc2cc(Cl)ccn12 +Cc1cccc(OCCNc2ccc(F)cc2N)c1 +Cc1cc(C)n(-c2cc(NC(=O)c3cc(C4CC4)on3)ncn2)n1 +Cc1nc(N2CCc3ccccc32)nc2c1C(=O)CC(C)C2 +CCc1ccc(OCC(O)Cn2c(CO)nc3ccccc32)cc1 +O=C(NCCc1ccccn1)c1cc2ccccc2[nH]c1=O +COC(=O)CC1C(=O)NCCN1Cc1ccnc(N2CCCC2)n1 +CC(C)n1cc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)cn1 +COC(=O)CN(Cc1cccc(C(=O)N2CCCCC2)c1)C(C)C +CC1Nc2ccc(C(=O)NC3CCCCC3)cc2NC1=O +CCc1cc(=O)[nH]c(-c2ccc(NCCNC(=O)C(C)(C)C)nc2)n1 +CCNC(=O)CSc1nc(C)nc(C)c1C(C)=O +O=C(Nc1ccnn1Cc1cccs1)c1cc2c(s1)CCC2 +CCc1cccc(CC)c1NC(=O)c1csc(COC)n1 +COc1cc(CN2CCCC(c3[nH]ncc3C)C2)cc(OC)c1OC +c1nc(-c2noc(-c3ccc4c(c3)OCO4)n2)n[nH]1 +Cc1cc(NC(=O)CCc2c(C)nn(CC(C)C)c2C)ccn1 +CSc1ncccc1C(=O)N1CCCCC1CN1CCOCC1 +CC(=O)Nc1nc(C)nc(-c2ccccc2)c1C(C)=O +N#CCOC(=O)c1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +CC(c1ccccc1Cl)N(C)C(=O)CNc1ccc(C#N)cc1 +CCOC(=O)CCCc1ccc2c(c1)NC(=O)CO2 +Cc1cnn(CCC(=O)Nc2ccc(OCc3nccn3C)cc2)c1 +Cn1c(C2CC2)nc2cc(-c3[nH]nc4c3CNCC4)ccc21 +COc1ccc(C(=O)N2CCC(c3ccccc3)C2)cc1 +Cn1cc(O)c(=O)cc1CN1CCN(Cc2ccccc2)CC1 +CN(C)C(=O)COc1cccc(CNc2nc3ccccc3s2)c1 +COc1ccc(-c2n[nH]c(SCC(=O)NCC3CCCO3)n2)cc1 +O=c1c2c3c(sc2n2nnnc2n1-c1ccccc1)CCCC3 +CS(=O)(=NC(=O)Nc1ccccc1)c1ccccc1 +CC1C(=O)N(c2ccc3c(c2)OCO3)CCN1C(=O)c1ccccc1 +Cc1cc(=O)n(CC(=O)NC2CCCC2)c(N2CCOCC2)n1 +O=C(CSc1cccc(C(F)(F)F)c1)Nc1cn[nH]c1 +CCc1cc(=O)n(CC(=O)NC(C)(C)C)c(-n2nc(C)cc2C)n1 +Cc1nc(C)c(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)s1 +Cc1ccc(CN(C(=O)Nc2ccc(-n3cncn3)nc2)C(C)C)o1 +Cc1nc(CNC(=O)c2ccnc(-n3cncn3)c2)c(C)s1 +Cc1ccncc1NC(=O)NCc1csc(-c2ccco2)n1 +Cc1ccsc1C(=O)NCc1ccccc1CN1CCCC1=O +COc1ccc(CNC(=O)NC2CCN(c3ccccc3)CC2)cc1 +CC(NC(=O)c1cc[nH]n1)c1ccc(S(C)(=O)=O)cc1 +CCNC(=O)c1cnc(-c2cccc(F)c2)nc1N +Cc1csc(CNc2ccc(-n3cccn3)c(Cl)c2)n1 +CC1CCC(NC(=O)c2cnc3sccn3c2=O)CC1 +CCc1cc(C(=O)Nc2cc(NC(C)=O)ccc2OC)sc1C +Cc1cccc(C(=O)NC2CCSc3ccc(F)cc32)c1C +CC(CC(=O)n1c(=O)oc2ccccc21)n1c(=O)oc2ccccc21 +O=C(CCNC(=O)C12CC3CC(CC(C3)C1)C2)Nc1ccncc1 +Cc1cc2[nH]c(=O)[nH]c2cc1NS(=O)(=O)c1cc(F)ccc1C +O=C(NCc1ccccn1)N(Cc1ccccc1C(F)(F)F)C1CC1 +COc1cccc(C(=O)N(CC(C)(C)C)CC(F)(F)F)n1 +COC(=O)c1sc(Cc2cc(OC)ccc2OC)nc1C +COc1ccc(CCNC(=O)c2nc3ccccc3c(=O)[nH]2)cc1 +Nc1c(-c2ccccc2)nsc1C(=O)Nc1ccncc1 +N#CCCC(C#N)Cn1nc(-c2ccc(F)cc2)ccc1=O +Cc1cc(C(=O)Nc2ccc(F)c(F)c2)ccc1-n1cnnn1 +Cc1ccc2c(c1)CCCN2C(=O)Cn1c(=O)cnc2ccccc21 +Cc1cc(NC(=O)c2ccc(S(=O)(=O)C(C)C)cc2)no1 +O=C(CCOCC1CCCO1)Nc1ccc(Cl)c(Cl)c1 +CCc1ccccc1N1CC(C(=O)NCc2ccccc2F)CC1=O +CCc1ccc(-n2nc(C)c3c(C)cc(=O)oc32)cc1 +N#CC1(NC(=O)c2cc(Br)c[nH]2)CCCC1 +CC(OC(=O)CCCc1c[nH]c2ccccc12)C(N)=O +Cc1ccc(CNc2cccc(C(=O)N3CCOCC3)c2C)cc1 +CC(C)c1n[nH]c(NC(=O)c2ccccc2S(=O)(=O)C(C)C)n1 +Cc1cnc2c(c1)nc(-c1cccs1)n2CCO +CC(=O)NCCNC(=O)CC(NC(C)=O)c1cccs1 +Cc1cc(NC(=O)CCc2cccc(Cl)c2)ccn1 +N#CC(C(=O)c1cccs1)c1nc2ccccc2s1 +CCCCc1ccc(-n2nnc(-c3ccncc3)c2N)cc1 +Cc1ccc(-n2ncc3cc(C(=O)NC4CC4)c(N)nc32)cc1 +Cc1nnc(SCC(=O)Nc2ccc(Br)cn2)o1 +Cc1ccc2cc(C(=O)Nc3ccc4[nH]nc(C(N)=O)c4c3)ccc2n1 +Cc1cc(C)cc(CC(C)NC(=O)NC2CCC(=O)N(C)C2)c1 +CCOc1cc(F)ccc1NCc1cn(C)nc1C +CC(=O)NCCCC(=O)NCc1sccc1C +O=C(COCC1CCCO1)NCc1cc(Br)cs1 +COc1ccc(C(=O)NCC(=O)Nc2cc(C)ccc2C)cc1 +CC(O)c1cccc(-c2ccc(F)c(Cl)c2)n1 +CCOc1ccc(C(=O)Nc2cccc(C(N)=O)c2)cc1OC +O=C(Cc1n[nH]c(=O)c2ccccc12)N1CCCC1c1cccs1 +COC(=O)C1(NC(=O)c2cc(F)cc3[nH]cnc23)CC1 +CCOc1ccc(F)c(C(=O)Nc2c(C)cccc2C)c1F +Cc1cc(C(=O)N2CCC(c3ccc4ccccc4c3)C(O)C2)no1 +COc1ccc(OC)c(CN(C(=O)C2CC2)C2CC2)c1 +CCOc1cccc(C(=O)Nc2ccc(OC)c(N)c2)c1 +Cc1ncc(CN(C)CC(O)c2ccc3c(c2)OCCCO3)s1 +O=C1C2CCC(CN(Cc3ccc(F)c(F)c3)C2)N1CC1CCC1 +Cc1ccncc1NC(=O)NCc1cn(C)nc1C(F)(F)F +Cc1cccc(SC2CCN(C(=O)c3ccno3)CC2)c1 +COc1ccc(OC)c(CC2CNc3ccccc32)c1 +O=C(CC1OCCO1)c1cccc(Cl)c1Cl +Cc1csc2nc(CNc3ccccc3-n3cncn3)cc(=O)n12 +COc1ccc(C)cc1Nc1ncnc2[nH]ncc12 +Cc1c(C(=O)NC2c3ccccc3CC2O)cnn1CCC(C)C +CC(=O)NCC(=O)Nc1ccccc1C(=O)C(C)C +NS(=O)(=O)NCC1CCCN(C(=O)c2cccc(Cl)c2)C1 +Cc1ccc2nc(C)cc(C(=O)N3CCC(Cn4cccn4)CC3)c2c1 +CC(C)(C)OCC(O)CN1CCN(c2ccc(F)cc2)CC1 +COCCn1c(C(=O)NCCc2ccccn2)cc2ccccc21 +CC(C)CC(NC(=O)c1cccs1)C(=O)N1CCc2nocc2C1 +CCOCC(O)CN1CCN(C(=O)Cc2ccc(C)nc2)CC1 +Cc1cc(NC(=O)NCc2cccc(NC(N)=O)c2)no1 +COc1ccccc1OCC(=O)NC1CCc2c(O)cccc21 +CC(=O)NC(C)C(=O)Nc1nc2ccc(OC(F)(F)F)cc2s1 +Cc1cc(NC(=O)Nc2ccc(C(C)C)cc2)no1 +Cc1c(C(=O)NCc2ccncc2)[nH]c2c1C(=O)CCC2 +O=C(CCCn1cncn1)NC(c1ccccc1)c1cccc(F)c1 +C=CCNC(=O)C(C)n1cnc2ccccc2c1=O +CSc1cccc(C(=O)Nc2nc(-c3ccccn3)cs2)c1 +O=C(Cc1ccc[nH]1)NCC(c1ccc(Cl)cc1)n1cccn1 +COCCNC(=O)c1ccc(-c2ccc(F)c(C)c2)nc1N +Cc1ccc(C(=O)NCC2(c3ccccc3)CCC2)c(=O)[nH]1 +CN(CC(N)=O)C(=O)Cc1cc2ccccc2[nH]c1=O +CC(C)OC(=O)Cn1c(C2CCCO2)nc2ccccc21 +Cn1cc(NC(=O)Nc2ccccc2F)cc(Br)c1=O +O=C(Cn1nnc(-c2ccsc2)n1)N1CCOCC1 +CCc1ccc(S(=O)(=O)NC(C#N)c2ccccn2)s1 +COc1cc2c(cc1C(=O)NCCOc1ccccc1)OCCCO2 +Cc1ccc(-c2csc(NC(=O)C3CCCO3)n2)c(C)c1 +CCNc1ccc(C)cc1C(=O)N(C)C(C)C1CC1 +COC(=O)C(NC(=O)c1ccccc1)=C1CCCCC1 +CCOc1ccc2nc(NC(=O)Cc3ccsc3)sc2c1 +Cc1ccccc1N1CC(C(=O)Nc2nccs2)CC1=O +CC(=O)c1ccc(NC(=O)c2cccc(-c3nnnn3C(C)C)c2)cc1 +C=CCOC(=O)C1=C(C)Nc2ncnn2C1c1ccccn1 +CC(NC(=O)Nc1nnc(C(F)(F)F)s1)c1ccco1 +O=S(=O)(NCc1ccco1)c1ccc(-n2cccn2)cc1 +O=C(Nc1ccc2c(c1)COC2)C1(Cc2ccccc2)CCC1 +CCCCN(CCCC)C(=O)C1CC(=O)OC12CCOC(C)(C)C2 +Cc1cccc(C)c1OC(=O)Cn1cnc2sccc2c1=O +COc1cccc(-c2cn(C)c3c(=O)[nH]cnc23)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)NCc1noc(C(C)(C)C)n1 +Cc1cc(C)n(-c2cc(-n3nc(C)cc3C)ncn2)n1 +CCc1ccsc1C(=O)N(C)Cc1ccc(O)cc1 +CC(C)=CCN1C(=O)C2CCC1CN(Cc1cccc(C#N)c1)C2 +Nc1ccc2c(c1)C(=O)N(Cc1ccc3c(c1)OCO3)C2 +Nc1c(C(=O)Nc2ccc(F)cc2F)oc2ccccc12 +CC(=O)OC1(C(F)(F)F)Oc2ccc(Cl)cc2NC1=O +COc1cccc(NCCC(O)c2ccc(C)c(N)c2)c1 +CCCNC(=O)Nc1cc2c(cc1N)OCCO2 +CCc1nnc(SCC(=O)NC2C3CC4CC(C3)CC2C4)o1 +Cc1ccccc1OCCN(C)c1c(C#N)c(=O)n(C)c(=O)n1C +CC1CN(C(=O)c2nc3sccn3c2-c2ncc[nH]2)CC(C)O1 +Cc1nnc(NC(=O)c2cccc3cccnc23)s1 +COc1ccc(NC(C)=O)c(NC(=O)CCC(=O)c2cccs2)c1 +COc1ccc(COCCCC(=O)N2CCOC(C)C2C)cc1 +Cc1ccc(CNC(=O)c2cc3nc(C)ccc3o2)cc1 +CCc1cc(CNC(=O)c2sc(-c3cccnc3)nc2C)on1 +CN(C)S(=O)(=O)C1CN(C(=O)OCc2ccccc2)C1 +O=C1CCC(COC(=O)c2ccc(NC(=O)c3ccco3)s2)N1 +N#Cc1nc(C2CC2)oc1N1CCN(C(=O)CCc2ccco2)CC1 +O=C(NC1CCCC1)C1CCC(=O)N1C1CCCC1 +CC(=O)c1sc(NC(=O)COc2c(C)ccc(C)c2C)nc1C +Cn1cc(S(=O)(=O)NCC(=O)Nc2ccc(Cl)cc2F)cn1 +CCCn1nccc1C(=O)NCc1ccc(F)cc1 +CC(C)N(Cc1ccccc1)C(=O)Cn1cnc2ccccc21 +Cc1c(F)cccc1S(=O)(=O)N1CCCC(Cn2cncn2)C1 +NC(=O)Cc1ccc(OCC(=O)Oc2ccc3ccccc3c2)cc1 +CCn1ccc(C(=O)N2CCCCC2CCNC(=O)C2CCCC2)n1 +NS(=O)(=O)CC1CCN(c2ncnc3sccc23)CC1 +CC(=O)NCc1ccc(C(O)Cc2ccccc2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)CSc1cccc(OC)c1 +COc1ccc(-c2cnnc(NCc3cnc(C)cn3)n2)cc1 +CC(C)CC1COCCN1C(=O)CCN1C(=O)COc2ccccc21 +Cc1nn(C)c(C)c1CCC(=O)NCc1ccc2c(c1)OCCCO2 +CCC(NC(=O)Nc1ccccc1OC)C(C)C +CC(C)NC(=O)Cn1nnc(-c2cccs2)n1 +NC(=O)N1CCCC(C(=O)NCCCc2ccccc2F)C1 +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1ccc2c(c1)CCO2 +CCCCS(=O)(=O)N(C)C(C#N)c1cccs1 +Cc1ccc(N2CCN(C(=O)c3cccc(C#N)c3)CC2)c(C)c1 +Cc1cc(CN(C)C(=O)NC2CCCCC2C)no1 +CSc1ccsc1C(=O)N(C(C)C)C1CCC1 +COc1ccc(NC(=O)c2cc(C)cc(C)n2)cc1 +O=C(Nc1ccc2ncccc2c1)c1c[nH]c2ccccc2c1=O +COCCOc1ccccc1NC(=O)CC1CCCC1 +NC(=O)Nc1ccc(-c2csc(CCc3ccccc3)n2)cc1 +COc1cc(C)ccc1OCC(=O)N(C)Cc1ccc(Cl)cc1 +Cc1cccc(CNC(=O)CCc2ccccn2)n1 +CCc1oc2ccccc2c1CNc1ccc2[nH]nc(C(N)=O)c2c1 +CC(=O)c1cc(C(=O)N2CCCc3cccc(OC(F)F)c32)n(C)c1 +CC(C)Cn1ncc(C(=O)OCC2CC2)c1C1CC1 +CCN(CCC(F)(F)F)C(=O)c1ccc2c(c1)CCC2 +Nc1ccc(CC2CCCN(S(=O)(=O)c3cn[nH]c3)C2)nn1 +Nc1ccc2nc(-c3ccc(F)c(F)c3F)nn2c1 +CS(=O)(=O)N1CCN(C(=O)c2ccc3c(c2)CCN3)CC1 +COc1cc(CNC(=O)NC(C)c2ccncc2)ccn1 +CN(C(=O)Cn1cc(C#N)c(=O)c2ccccc21)C1CC1 +CC(C)S(=O)(=O)NCc1ccnc(OC2CCCC2)c1 +O=C(COc1ccc2c(c1)CCC2)Nc1cc(F)ccc1F +CC(=O)N1CCc2cc(NC(C)C(=O)Nc3cc(C)no3)ccc21 +Cc1ccc2nc(NC(=O)Cn3cnc(C#N)n3)sc2c1 +Cc1[nH]nc(-c2ccc3oc(=O)[nH]c3c2)c1Br +Cc1cc(=O)oc(C)c1C(=O)NCc1ccccc1 +Cc1cc(C)n(C(=O)CCCOc2ccccc2F)n1 +Cc1nn(CCO)c(C)c1CNCCc1cc(F)cc2c1OCOC2 +CC(C)N(CCCNC(=O)c1ccccc1Cl)S(C)(=O)=O +CC1Cc2ccc(F)cc2CN1S(=O)(=O)CC1CCOCC1 +CC(=O)c1ccc(-c2ccccc2NC(=O)c2ccccn2)s1 +CNC(=O)c1cc(C(=O)c2ccc(C(F)(F)F)cc2F)c[nH]1 +CN(Cc1cccs1)c1ccc(N)c2nonc12 +Cc1cccc(NC(=O)C2CCN(c3ccc4c(c3)OCO4)C2=O)c1 +CCc1n[nH]c(SCc2nccn2Cc2ccccc2)n1 +COc1c(C)cc(NC(=O)N2CCCCC2CO)cc1C +CCc1nc(C)c(C(=O)N2CCCN3C(=O)c4ccccc4C32)o1 +CCOc1ccccc1OCc1nnc(SC(C)C#N)n1N +CN(CCCNC(=O)OC(C)(C)C)C(=O)Nc1ccc(C#N)cc1 +CC(C)C1C(=O)NCCN1C(=O)c1ccc2[nH]cnc2c1 +CS(=O)(=O)c1cccc(C(=O)NCC2CCCCC2)c1 +c1ccc(-c2nc(CCNCc3ccco3)co2)cc1 +N#Cc1ccc(C(=O)NCCNC(=O)c2ccco2)cc1 +Cc1ccc(-c2nnc(C3CC3)o2)cc1Br +CCN(C(=O)CSc1ncccn1)c1ccccc1 +CN(Cc1ccc(C(C)(C)C)cc1)Cc1cc(=O)n(C)c(=O)n1C +Cc1ccc(C(C)NC(=O)C2CCCCN2C(=O)c2cccs2)o1 +COC(=O)NCC(=O)NC1CCc2c(Cl)cccc21 +COc1ccc(NC(=O)COc2cccc(C)c2)c(OC)c1 +O=C(c1ccncc1)N1CCOC2C(CNc3ncccn3)CCC21 +CCCCNC(=O)C1CCN(c2ccccc2F)CC1 +Cc1csc(SCc2cccc(C(N)=O)c2)n1 +COc1ccc(CNC(=O)CC2NC(=O)c3ccccc32)c(F)c1F +O=C(c1ccc2[nH]cnc2c1)N1CCc2noc(-c3ccccc3)c2C1 +CC1(NC(=O)Cn2cc(-c3ccccc3)nn2)Cc2ccccc2C1 +O=C(COC1CCCCC1)Nc1cccc(OCc2cccnc2)c1 +CCN(CC)C(=O)CCCNC(=O)Nc1ccc(C)c(Cl)c1 +O=C(Nc1nccs1)c1ccccc1SCC(=O)N1CCCC1 +CC(C)C(=O)Nc1ccc(CNS(C)(=O)=O)cc1 +CC(CC#N)N1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1 +COC(=O)CNC(=O)c1nccc2c(N)ccc(F)c12 +CC(=O)NC1CCCN(C(C)C(=O)Nc2cc(C)no2)C1 +Nc1ccccc1C(O)CSc1cccc(Br)c1 +CC(=O)NCCC(=O)Nc1ccc(F)c(F)c1F +CCCn1nnnc1COC(=O)c1cc(OC)c2c(c1)OCCO2 +O=C(C1CCCN1c1ccc(Br)cn1)N1CCOCC1 +CN(Cc1ccc(C#N)cc1)C(=O)Nc1cnn(C)c1 +O=S(=O)(CCCNc1ncccn1)c1ccccc1 +COc1ccccc1NC(=O)CCN1CCN(CC(F)(F)F)CC1 +CN(C(=O)Cc1ccccc1)C(C#N)c1cccnc1 +COc1cccc(OCC(=O)Oc2cccc(F)c2)c1 +Cc1c(Br)c(=O)[nH]c(=O)n1Cc1ccccc1 +CC(C)(C)CC(=O)NCCc1nc2ccccc2s1 +CCOC(=O)c1ccc(Nc2cc(N)ccc2Cl)nc1 +CCC(=O)Nc1cccc(NC(=O)c2cc(-c3ccccc3)no2)c1 +NC(=O)C1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 +COc1ccc2cc(S(=O)(=O)N3CCCC3)c(=O)oc2c1 +CCc1nc(CNc2ccccc2OCC(C)C)no1 +CC(=O)NCCNC(=O)c1sccc1-c1ccc(F)cc1 +COC1(C)CC(NC(=O)NCc2ncn(C)n2)C1(C)C +CCSc1nnc(NC(=O)C2CN(C(C)=O)C2)s1 +NC1C(=O)N(CCOc2ccccc2)c2ccc(Cl)cc21 +CS(=O)c1ccc(NC(=O)NCCCn2cccn2)cc1F +CCCC(C)NS(=O)(=O)c1cccc(-n2cnnn2)c1 +OC(Cc1c(F)cccc1Cl)c1ccccn1 +Cc1nnc2n1CCN(C(=O)c1n[nH]c3c1CCCC3)C2 +Cn1c(SCc2noc(-c3cccs3)n2)nnc1C1CC1 +CN(C)c1cccc(CNC(=O)c2cc(=O)c3ccccc3[nH]2)c1 +O=C(NCc1nncn1C1CC1)Nc1ccccc1OCC1CC1 +CC(=O)Nc1ccc(C(=O)Nc2cc(C)ccc2O)cc1 +N#Cc1ccc(NC2CCc3nnc(-c4ccc(F)cc4)n3C2)nc1 +Cc1cc(C)c(CNC(=O)CCC(=O)N2CCOCC2)c(C)c1 +CC(C(=O)OC1CCCCC1C#N)N1CCc2ccccc2C1 +COc1ccc(OC)c(C(=O)COc2ccccc2N)c1 +CCn1c(SCCn2cccn2)nc2ccccc2c1=O +O=C1COc2ccc(C(=O)OCC3CCCCC3)cc2N1 +Cc1ccc(Cl)c2c1CCNC2c1ccc[nH]c1=O +CN(C)C(=O)c1ccc(C(=O)NCCCCn2ccccc2=O)cc1 +Cc1ccc2[nH]c(SCCn3c(C)csc3=O)nc2c1 +CCOC(=O)CC1NCCc2cc(Cl)c(O)cc21 +CCNc1nc(-c2cnn(CC)c2)cc(C(F)(F)F)n1 +COc1ccc(NC(=O)C2(NC(=O)c3ccco3)CCCC2)cc1 +CN(CC(=O)Oc1ccccc1Cl)S(C)(=O)=O +Cc1cccc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)c1 +CC(=O)c1cccc(S(=O)(=O)NC(C)Cc2ccccc2F)c1 +COCCNS(=O)(=O)c1cnn(C2CCCCC2)c1N +C#CCN1CCC(C(=O)N2CC(c3ccccc3C)CC2C)CC1 +CCn1ncnc1C(C)NC(=O)Cc1cc(F)ccc1C +O=C(Nc1cccc(Br)c1)c1ccsc1 +O=C(COc1ccc2c3c(c(=O)oc2c1)CCCC3)NCCCO +CCc1ccccc1NC(=O)CNC(=O)NC(C)C +COc1cccc(OC)c1Cc1nc(Cc2noc(C)n2)no1 +COc1ccc(C(NC(=O)N(C)CC2CCCO2)C(F)(F)F)cc1 +Cc1cccc(-n2ncc(C#N)c2NC(=O)C2CC2)c1 +C=CCN(CC=C)C(=O)NC1CCN(c2ccc(C#N)cn2)CC1 +CCN1CCN(CCCOc2ccc3c(c2)CCC3)C(=O)C1=O +O=C(NCc1cscn1)N(Cc1ccco1)Cc1cccs1 +Cc1cc(C)c(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)o1 +CC(CCc1ccco1)NC(=O)NCC1CCC1 +Cc1nc(CSc2nc3ccc(C(F)(F)F)cc3[nH]2)no1 +CN(C)C(=O)c1cccc(OC(=O)CCSc2ccccc2F)c1 +Cc1ccc(F)cc1NC(=O)c1cc(N)cnc1C +CC(=O)Nc1cc(F)c(F)cc1NCc1noc(C(C)C)n1 +CCOC(=O)COC(=O)c1cn(C)nc1-c1cccs1 +CC1CN(C(=O)C2COc3ccc(F)cc3C2)c2cccnc2O1 +O=S(=O)(NCCCOC1CCCC1)c1cccs1 +CCc1ccccc1OC(=O)COCC1CCCO1 +O=C1CCC(N2CCN(c3ccccc3Cl)CC2)N1 +O=C(c1cnccn1)N1CC2CCc3nnc(-c4ccccc4)n3C2C1 +CC(=O)NCC(=O)N1CCOC2(CCCC2COc2ccccn2)C1 +COc1ccc(Cc2nnc3sc(-c4ccncc4)nn23)cc1 +Cc1cc(=O)n2nc(NCCCCOc3ccccc3)sc2n1 +Cc1cccc(C(=O)N2CCC(C(O)c3ccccc3)CC2)c1C +CNC(=O)c1cn[nH]c1C1CCCN1C(=O)c1cnccn1 +NC(=O)Nc1cccc(NC(=O)CCOCc2ccccc2)c1 +C=CCC1(C(=O)OCC)CCCN1C(=O)OC(C)(C)C +O=C1c2ccc(O)c(Cl)c2CN1C1CCCCC1 +CN(C)C(=O)C1CCN(C(=O)c2ccccc2Cl)CC1 +Cc1csc(N2CCCN(C(=O)c3ccc4c(c3)CCC4)CC2)n1 +Cc1nnc(C(C)NCC(c2ccc(C)s2)N2CCOCC2)o1 +COc1ccc(CCNC(=O)CSc2nnnn2C)cc1 +CC(C)(C)CC(=O)NCCCN1CCCCCC1=O +CN(C(=O)c1nc(N2CCCC2)ncc1Cl)C1CC1 +C#CCN1CCN(CC(=O)NCCc2ccc(F)cc2)CC1 +COc1cc(OC)c(CNC(=O)N2CCCCC2C)c(OC)c1 +O=C(CCn1ccccc1=O)N(Cc1ccccc1)CC1CCC1 +Cc1ccc(C)c(OCCN2CC(CO)CC2=O)c1C +CCOC(=O)c1nn(C)c2c1CN(Cc1cccc(O)c1)CC2 +CCc1c(C(=O)N2CCc3ncnc(OC)c3C2)cnn1CC(C)C +O=c1c2ccccc2ncn1S(=O)(=O)c1ccccc1 +Cc1nc2cc(Br)ccn2c1C(C)O +Cc1ccc(NCCC(O)c2ccc3c(c2)OCCO3)cc1 +CC1(CNC(=O)CNC(=O)COc2ccccc2)CCCC1 +C=CCN(Cc1ccc(C#N)cc1)C(=O)c1ccc(-n2cccn2)nc1 +CC1CN(C(C)C(=O)Nc2ccccc2-c2ccccc2)CCO1 +COc1ccc(C2CC(C)c3nc(N)nn3C2)cc1Cl +O=C(CNC(=O)c1cc2ccoc2s1)NCc1ccccc1 +COCC1=NC(=O)C2(CCN(C(=O)NC3CCCCC3)CC2)N1 +Cc1ccccc1NC(=O)c1ccc(CNC(N)=O)cc1 +CCc1sc(C(=O)Nc2ccc(CN3CCOC3=O)cc2)cc1C +CCn1ccnc1Cn1nc(C)c(Br)c1C +O=C(c1ccsc1)N1CCC(OCc2ccccn2)C2OCCC21 +COc1cc(C(=O)Nc2ncccc2C)cc(OC)c1C +CCCCCCN1CC2(CCN(C(=O)c3cnn(C)c3)CC2)OC1=O +CC(NCC(=O)NCC(=O)N1CCCC1)c1ccc(Cl)cc1 +O=C(c1c(F)cccc1F)N(CCc1cccs1)Cc1ccoc1 +CN(Cc1ccccc1F)C(=O)c1ccc(NC(N)=O)cc1 +Cc1cccc2c1N(CC(C)C)C(=O)C21OCCO1 +CNC(=O)c1cccc(OC(=O)CC2CCCC2)c1 +CNS(=O)(=O)c1ccc(NC(=O)NC(C)(C)c2ccccc2)cc1 +N#Cc1cnn2c3c(cnc12)C(=O)CC(c1cccc(Cl)c1)C3 +Cc1ccc(C)c(S(=O)(=O)CC(=O)NC(C)c2ccc(F)cc2)c1 +CCc1cc(=O)[nH]c(Nc2cc(C)ccc2OC)n1 +CC(NC(=O)CN1CCCNC1=O)c1cccc(Cl)c1Cl +COC(=O)C1=C(C)Nc2ncnn2C1c1cccc(F)c1 +COC(=O)C(NS(=O)(=O)c1cccc(C)c1)C(C)C +CC(c1ccco1)N(C)C(=O)C1CCCN(C(N)=O)C1 +COc1ccc(N)cc1N1CCN(C(=O)C(C)(C)C)CC1 +CCC(C(=O)NCCCNC(C)=O)c1ccccc1 +Cn1c(=O)c2ncn(CC(=O)NC3CCCCCC3)c2n(C)c1=O +CCNC(=O)N1CCC(c2nnc(-c3ccc(OC)cc3)o2)C1 +CCn1c(C)cc(C)c(-c2nnc(NCC(C)C)s2)c1=O +COc1ccc(CNC(=O)c2cnc3ccc(C)cn23)c(OC)c1 +NC(COC(F)(F)F)c1ccccc1Br +NC(=O)c1ccc(NCC(=O)Nc2cc(Cl)ccc2F)cc1 +COc1ccc(-c2nnc3c4ccccc4c(C)nn23)cc1N +Cc1cccc(C(=O)N(C)C(C)c2ccc(S(C)(=O)=O)cc2)n1 +Cc1occc1C(=O)Nc1ccccc1OCC1CC1 +Cc1cccc(OCC(O)Cn2nc(-c3cccs3)oc2=O)c1 +Cc1ccc2cc(CN(C)C(=O)CC(C)C)c(=O)[nH]c2c1 +COC(=O)c1cc(Cn2c(-c3ccccc3)noc2=O)c(C)s1 +CC1CCc2sc(C(=O)NCCc3nnc4ccccn34)cc2C1 +CN1C(=O)COC2CN(C(=O)c3cnc4ccccc4c3)CC21 +Cc1cc(C(C)(O)CNC(=O)CCn2cnc3ccccc32)c(C)o1 +CCn1cc(C(=O)NCC(C)(C)c2ccncc2)cn1 +CCCS(=O)(=O)N1CCc2nc(NC(=O)OC)sc2C1 +COc1ccc(-c2noc(C(=O)NCC(C)C)c2N)cc1 +CCC(C)N(C)S(=O)(=O)c1cc(Br)cnc1N +Cc1noc(C)c1CCCNC(=O)N1CCCN(CC(F)F)CC1 +CC(Sc1nncn1-c1ccccc1F)C(=O)NC1CCCC1 +COc1ccc(N(C)C(=O)c2ccc(C(C)=O)cc2)cn1 +CC1(C)CN(C(=O)C2Cc3ccccc3S2)CCO1 +COc1ncccc1NC(=O)N1CCN(C(=O)c2cnccn2)CC1 +Oc1ccc(NCc2ccc(O)c(F)c2)c(F)c1 +Cn1cnc(CNC(=O)N(Cc2cccs2)CC2CCCO2)n1 +Cc1nnc(SCC(=O)c2ccn(C)c2)n1C +Cn1c(COc2cccc(C(F)(F)F)c2)nnc1SCC(N)=O +CCOc1ccc(NC(=O)c2cnc3cc(C(C)=O)[nH]c3c2)cc1 +CC(NC(=O)C1CCC1)C(=O)NC(c1cccs1)C(C)C +COc1cccc(OCC(=O)Nc2cc(F)c(F)c(F)c2)c1 +Nc1cncc(S(=O)(=O)NCCN2CCOCC2)c1 +CC(=O)NCCC(=O)NCCOc1ccc2c(c1)CCC2 +O=C(CSc1ncn[nH]1)NC1CCc2c(Cl)cccc21 +O=C(c1cccnc1)N1CCOC(c2cc[nH]n2)C1 +Cc1cccc(C)c1OCCNC(=O)NC(C)C1CC1 +CN(CCOCC1CC1)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +Cc1cc(Cl)ccc1NC(=O)c1ccc(CNC(N)=O)cc1 +CC(=O)c1ccc(NC(=O)c2ccc(O)cc2)cc1 +Cc1nn(CCC(=O)NC(c2ccccc2)c2cccnc2)c(C)c1C +O=c1cc(-c2ccccc2)[nH]c2c(Cl)cc(F)cc12 +CCc1ccc(C(=O)N2CCC2)cc1S(=O)(=O)N1CCOCC1 +Cc1ccc(-n2c(SCCCC#N)nnc2-c2ccncc2)cc1C +COc1ccc(C(=O)N(Cc2cccn2C)C2CC2)cc1 +N#Cc1ccc(Cl)cc1S(=O)(=O)NCCCO +CN(C(=O)c1cn(Cc2cccs2)nn1)c1cccc2ncccc12 +CCc1onc(C)c1NC(=O)c1cnn(C(CC)CC)c1C +O=C(Cn1c(=O)cnc2ccccc21)N1CCOCC1 +O=C1OCCN1CCc1nc(-c2ccc(F)c(F)c2)cs1 +CC1CCCN(c2ncnc(Nc3nccs3)c2N)C1 +Cc1noc(-c2cccn(Cc3cc(=O)n4ccccc4n3)c2=O)n1 +CCCn1nc(-c2ccc(OC)cc2OC)cc(C#N)c1=O +CC(C)(C)c1nc2ccc(OCCCO)cc2s1 +CCC1Nc2cc(OC)ccc2N(CCCC#N)C1=O +Cc1cc2c(SC(C)C(=O)N3CCCCC3)ncnc2s1 +COCc1nc(CCc2ccccc2)sc1C(C)(C)O +Cc1cc(Oc2ccc(C#N)cc2)ccc1NC(=O)c1cnn(C)c1C +O=C(CNC(=O)C1CCCC1)N=c1[nH]nc2ccccn12 +Cc1nn(C)c(C)c1CCNC(C)c1ccc(-n2ccnc2C)cc1 +O=C(NC(Cc1ccccc1)c1nnc(N2CCCC2)o1)C1CC1 +Cn1ccc(C(=O)NC(c2ccccc2)c2ccc(F)cc2)cc1=O +O=C(Nc1ccc(-n2cccn2)c(F)c1)OCC(F)(F)F +Cc1csc(NC(=O)C2CCN(C(=O)CCc3ccco3)CC2)n1 +COc1ccc2c(CC(=O)NC(C)c3cccs3)cc(=O)oc2c1 +Cc1ccc(C(=O)NCCNC(=O)C2CC3C=CC2C3)cc1F +NC(=O)Cc1ccc(Oc2ncc(-c3cccs3)cn2)cc1 +Cc1cccc(N2CCN(Cc3nccn3C(F)F)CC2)c1C +COc1ccc(O)c2c1C(c1cnccc1Cl)NCC2 +CN1CCC(NC(=O)CCc2ccccc2OC(F)(F)F)C1=O +CC(C)n1nc(-c2ccccc2)cc1NC(=O)N(CCC#N)C1CC1 +CCOC(=O)C1(NC(=O)Cc2c(C)nn(C)c2C)CCCCC1 +C=CCn1c(CN(C)C(=O)c2cccnc2)nc2ccccc21 +Cc1nnc(SCC(=O)Nc2nc(-c3ccccc3)cs2)n1C +CC(=O)Nc1ccc(-c2nccn2Cc2ccccc2C#N)cc1 +c1csc(Cc2nnc(SCCC3OCCO3)o2)c1 +Cc1nnc2c(Nc3ccc4c(c3)OCO4)nc3ccccc3n12 +O=C(COc1ccc(Oc2ccccn2)cc1)Nc1nncs1 +CN(CC(=O)NC(C)(C)C)C(=O)Nc1ccc(-c2csnn2)cc1 +Cn1nc2n(c1=O)CCN(Cc1ccc(F)c(F)c1)C2 +CC=Cc1ccc(OC(=O)Cn2c(C)c(C)sc2=O)c(OC)c1 +O=C(CCn1ccccc1=O)N(Cc1ccccc1)c1ccccc1 +CN(Cc1ccc(C#N)cc1)C(=O)Nc1cccc(F)c1F +CCC(C)n1nccc1NC(=O)c1cccc(Nc2cnn(C)c2)c1 +COc1cccc(C(=O)N2CCN(C(=O)OCC(C)C)CC2)c1F +COc1cc(C#N)ccc1OC(C)C(=O)Nc1ccccc1C +CSc1cccc(-n2nnc(C(=O)NCC3CCCO3)c2N)c1 +COc1cccc2c1N(C(=O)c1cnc3c(c1)c(C)nn3C)CCC2 +CCNC(C)(C#N)c1ccccc1Br +Cc1cc(C(=O)NCc2csc(C3CC3)n2)c(C)o1 +COc1ccc(OC2CCN(C(=O)c3ccon3)CC2)cc1 +O=C(NCc1cccc(Cl)c1)c1cnc(C2CCCO2)s1 +N#Cc1ccccc1CS(=O)(=O)Nc1cccc(CO)c1 +NC(=O)c1ccc(-c2nc(-c3cccc(Br)c3)no2)nc1 +CCOc1ncccc1C(=O)Oc1ccc(OC)cc1 +CCOC(=O)c1sc(NC(=O)c2cccnc2OCC)cc1C +Cc1nnc(SCc2csc(C3CCCO3)n2)c(C#N)c1C +Cc1cc(C(=O)N2CCCCC2)c2c(C)nn(C)c2n1 +O=C(CSc1ccncc1)Nc1ccc(OC(F)F)c(F)c1 +CC1(C(=O)N2CCCC2Cn2cccn2)CCOCC1 +CCc1ccc(OC(C)C(=O)Nc2ccc(CC(=O)NC)cc2)cc1 +Cc1cc(C)n2ncc(-c3noc(-c4nc5nccc(C)n5n4)n3)c2n1 +COC(=O)CC1CCCCN1C(=O)c1cnn(C)c1C +CNC(=O)NCC(=O)N(Cc1ccccc1OC)C1CC1 +COc1ccc2oc(C(=O)NCC(F)(F)F)c(C)c2c1 +Brc1cnc(NCc2ccco2)nc1 +CCNC(=O)NC1CCC(OC(=O)COc2ccc(C)cc2C)CC1 +COc1ccc(S(=O)(=O)NCCOc2ccc(F)cc2)cc1F +CC(NC(C(N)=O)c1ccccc1)c1cc(F)ccc1F +CC(=O)NCCCSc1nc2cc(Cl)ccc2n1C +CCC(=O)Nc1nc(-c2ccc3c(c2)N(CC)C(=O)CO3)c(C)s1 +CCc1cc(N(Cc2ccccc2)C(C)CCO)n2ncnc2n1 +CS(=O)(=O)c1ccc(Cc2nc(Cc3ccccc3)n[nH]2)cc1 +CCCNC(=O)c1cnc(COc2ccccc2F)nc1N +CCc1nnc(NC(=O)CCCn2c(C)csc2=O)s1 +CC1=Nc2nnnn2C(c2cccc(Br)c2)C1C(N)=O +Cn1cc(CN2CC3OCCN(c4ncccn4)C3C2)cn1 +O=C(Nc1ccccn1)c1ccc(CS(=O)(=O)c2ccccc2)o1 +Cc1ccc(C(=O)N2CCCC3(CCN(c4cccnc4)CC3)C2)cc1 +O=C(NC1CCCC1)c1cncc(-c2ccc(F)cc2)c1 +CCC1Nc2cc(OC)ccc2N(CC(=O)NC)C1=O +CC(C)N(Cc1nccn1Cc1ccc(F)cc1)C(=O)C1CCC1 +CC(C)N1CCC2(CCCN2C(=O)OC(C)(C)C)C1=O +CC(CO)NC(=O)NCc1ccccc1CN1CCCC1=O +CC(CNC(=O)NCCc1ccc2c(c1)OCO2)N1CCOCC1 +CCOC(NC(=O)CC)(C(F)(F)F)C(F)(F)F +COc1ccc(CO)cc1-c1cc(F)cc(F)c1 +CCOCCC(=O)NCc1cccc(-c2n[nH]c(C)n2)c1 +CCOc1coc(C(=O)Nc2ccc(C)cc2)cc1=O +O=C(NCCCNc1ncccn1)Nc1nccs1 +COc1ccc(N2CCN(C(=O)c3ccnnc3)C(C)C2=O)cc1 +O=C1CCc2cc(S(=O)(=O)Nc3ccc4[nH]ncc4c3)ccc2N1 +O=C(c1cc(F)cc(F)c1)c1cccc(C2OCCO2)c1 +Cc1nn(C)c2[nH]nc(NC(=O)c3ccc(OCC4CC4)cc3)c12 +COc1ccc(NS(=O)(=O)c2ccc(Cl)cc2F)cn1 +Cc1ccc(-n2nc3c(N4CCCC4)nnc(C)c3c2C)cc1 +COc1ccccc1NC(=O)Nc1ccc2snnc2c1 +Cc1ccc(CNC(=O)c2c(F)cccc2F)cc1 +CCNc1nnc(-c2c(C)oc3c2CC(C)CC3)s1 +Clc1ccncc1NCc1ccc2cc[nH]c2c1 +CCOC(=O)N1CCN(C(=O)c2ccc(-c3cnn(C)c3)nc2)CC1 +COc1ccc(-c2noc(-c3ccc(N4CCCC4)nn3)n2)cc1 +COC(=O)CNC(=O)C(N)c1cc(F)ccc1F +O=C(Cc1ccccc1Cl)Nc1ccc(N2CCNC2=O)cc1 +Clc1ccccc1-c1nnc(CSc2ncnc3nc[nH]c23)o1 +CC(=O)NC(C(=O)N(C)c1nc2ccccc2s1)C(C)C +CC(C)(C)OC(=O)N1CCN(C(=O)c2c[nH]c(=O)[nH]2)CC1 +O=C(NCCN1CCOCC1)NCC12CC3CC(CC(C3)C1)C2 +COC1CCCC1OC(=O)CCc1nnc(-c2ccc(C)cc2)o1 +COC(=O)C1CC2CCCCC2N1S(=O)(=O)c1cnn(C)c1 +NC(=O)CCSc1ccccc1NC(=O)NCc1ccccc1F +O=C(Nc1ccc(-c2nn3cnnc3s2)cc1)c1ccco1 +c1nc2ccc(C3NCCc4ccc5c(c43)OCO5)cc2[nH]1 +Cc1cc(CNC(=O)c2cc(C3CC3)n(C(C)(C)C)n2)c(C)o1 +Cc1cccc(CNC(=O)Cn2ncn(C)c2=O)c1 +COc1ccc(NC(=O)Cc2cccc(F)c2)c(N)c1 +N#Cc1cc(Br)ccc1NCC(O)C1CC1 +Cc1ccc2nc(C(C)(C)C)c(C(N)C(F)(F)F)n2c1 +CCCc1nnc2sc(CN3CC(C)OC(C)C3)nn12 +CC(C)C(NC(=O)c1ccc2c(c1)nc(C(F)(F)F)n2C)C(N)=O +C=CCn1c(NC(C)CC)nc2c1c(=O)n(C)c(=O)n2C +CCn1c(SCC(=O)Nc2ccncc2)nnc1-c1cccs1 +CCOC(=O)c1c[nH]c2c(F)c(F)ccc2c1=O +O=C(NCc1ccc(N2CCCCC2=O)cc1)N1CCC(CO)CC1 +CC(=O)Nc1nc2ccc(C(=O)NCCCc3ccco3)cc2s1 +CCOC(=O)n1c(=O)n(Cc2ccc(OC)cc2)c2ccccc21 +CCC(CC)NC(=O)COC(=O)c1c[nH]c2ccccc12 +Cc1ccc(C)c(C(=O)CNC(=O)c2cccs2)c1 +Cc1cccc(OCC(=O)Nc2ccc3c(c2)OCCO3)c1C +Cc1oc(C(=O)OC(C)CC(C)C)cc1S(=O)(=O)N(C)C +COC(=O)c1sc(NC(=O)c2ccc(C)nc2)nc1C1CC1 +CN(Cc1ccco1)S(=O)(=O)N1CCCCC1 +CCc1ccsc1C(=O)N(C)Cc1cccnc1 +COc1ccc(-c2ccc(-n3ncc(C#N)c3N)nn2)cc1C +Fc1cccc(-n2cccn2)c1NCc1nnc(C2CC2)o1 +Cc1cc(CCOc2ccccc2)c(C#N)c(=O)[nH]1 +Cn1ccnc1S(=O)(=O)CC(=O)N(Cc1ccccc1)C1CC1 +O=C(NCc1ccccc1)c1cc2sccn2c1 +COc1cc(Cl)c(C)cc1NC(=O)CCn1nc(C)cc1C +CCn1cc(NC(C)c2cccc(O)c2)ccc1=O +CCn1nc(C(=O)NCc2ccccc2C)c(=O)c2ccccc21 +CN(Cc1ccncc1)S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +COc1ccc(CNC(=O)C2CC(=O)N(c3cccc(C)c3)C2)cc1 +COC(=O)C(C#N)CC(=O)c1ccc(OC)c(Cl)c1 +C=CCN1CCOC2CCN(c3ccc(C)nn3)CCC21 +Cc1cccc(CN(Cc2cc(C)on2)Cc2cc(C)on2)c1 +CCN(CCO)S(=O)(=O)c1ccc(S(C)(=O)=O)cc1 +Cc1cc(Cl)ccc1C(=O)N1CCCC(O)(CO)CC1 +O=C(NC1CCN(C(=O)Cc2ccsc2)CC1O)c1cccnc1 +CCC(C)C(=O)N(CC(N)=O)Cc1ccc(Br)cc1 +NC(=O)C1CCN(C(=O)NCc2ccc(F)cc2C(F)(F)F)C1 +Cc1ccc(NC(=O)Cc2noc(CNC(=O)C3CCCC3)n2)cc1 +CCc1nnc(SCC(=O)Nc2cccc(F)c2)n1N +O=C(NCCCc1ccccc1)N1Cc2cncnc2C1 +O=C(CCS(=O)(=O)c1ccccc1)NC1CC(O)C(CO)C1 +CC(C)Oc1ccc(C(C)NC(=O)CCn2cncn2)cc1 +COCc1nc(COc2ccccc2C)sc1C(C)=O +COc1ncccc1CNC(=O)c1ccc(O)c(Cl)c1 +CCOc1ccccc1C(=O)Nc1ccc(-n2cnnn2)cc1 +NS(=O)(=O)c1ccc(CC(=O)NCc2cc(F)cc(F)c2)s1 +CCC1COCCN1Cc1cn(-c2ccccc2)nc1C +Cc1ccc(C#N)cc1NC(=O)N(C)Cc1ccco1 +Cc1n[nH]c(SCc2nnnn2-c2ccc(C(F)(F)F)cc2)n1 +CC(NC(=O)NC(C)C(C)C)C(=O)N1CCCCC1 +Cc1ccc2nc(C3CC3)cc(C(=O)NCCC(=O)N(C)C)c2c1 +CCOc1c(Br)cc(C)cc1C(=O)CCC(=O)OC +COc1ccc(NC(=O)c2ccco2)cc1OC(F)F +CCN(CC)C(=O)c1ccccc1NC(=O)NCC(=O)NC1CC1 +O=C(N=c1[nH]nc2ccccn12)c1cc(-c2ccco2)[nH]n1 +CC(C)CNC(=O)N(C)Cc1ccc2c(c1)OCCO2 +COc1cc(C)sc1C(=O)NC(C)Cc1ccccc1F +Cc1nc(C)c(C(=O)NC2CC(=O)N(Cc3ccccc3)C2)s1 +COc1cc(OC)c(C(=O)Nc2cc(Cl)ccc2O)cc1OC +NC(=O)NCCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +CC(=O)c1cc(CCC(=O)Nc2cc(F)cc(F)c2)oc1C +CC1(NC(=O)NCc2ccc(C(N)=O)cc2)Cc2ccccc2C1 +Cc1nccc(C(=O)N(CCC#N)Cc2ccco2)n1 +CCC(C)NC(=O)NCCNC(=O)c1ccccc1 +CN(CCc1ccccn1)C(=O)c1cnc2ccccn2c1=O +Cc1cccc(C)c1-n1nnnc1SCC(=O)NCC(C)C +CC(C)Nc1nc(C(=O)Nc2ccc3c(c2)OCCO3)cs1 +O=S(=O)(c1cccc(Cl)c1)N1CCNCC1 +Cc1ccc(-n2nnc(C(=O)Nc3cc(F)ccc3F)c2N)cc1C +Cc1ocnc1C(=O)Nc1ncccc1-c1ccccc1 +O=c1cc(-c2ccncc2)nc(N2CCCCC2)[nH]1 +COc1ccc(Cl)c(NC(=O)CCOC(C)C)c1 +Cc1ccc(C(=O)NC(CN2CCOCC2)c2ccccc2)cc1F +CC1CC(c2ccccc2)C(C)N1C(=O)C1CCCO1 +O=C(COc1ccccc1F)N1CCCC1c1cc[nH]n1 +Cc1ccc(CN(C(=O)c2csnc2C)C(C)C)o1 +CN(Cc1ccc(F)cc1)C(=O)COc1ccccc1C#N +Cc1cc2c(NCCO)nc(-c3cccnc3)nc2s1 +CCc1cnc(CN(C)C(=O)NC2CCN(C)C2=O)s1 +COC(=O)c1cccc(CNC(=O)NC(C)c2ccc(C)o2)c1 +CN(Cc1cnn(C)c1)C(=O)c1ccc(-n2cccc2)cc1O +Cc1cc(C)cc(OC(=O)C23CCC(C)(C(=O)O2)C3(C)C)c1 +CC1(C)CN(CCC(=O)c2ccc(Cl)cc2)CCO1 +CC(C)C(=O)Nc1cccnc1SCc1ccccn1 +Nc1ccc(N2CCOCC2)cc1N1CCOCC1 +Cc1ccccc1-c1nnn(CC(=O)NC(C)C(C)C)n1 +CCN(c1ccc(NC(=O)c2sc(C)nc2C)cc1)C(C)C +CCC(C)NC(=O)CNc1ccc(SC)cc1 +CCOc1ccccc1NC(=O)NCc1ccnc(OC)c1 +CCOC(=O)Cc1ccc(Br)c(F)c1 +O=C(NC1CCCC1)c1nc(-c2ccccc2F)cs1 +O=C(NCC(=O)N1CCCC1)c1c(F)cccc1Cl +COc1ccccc1NC(=O)COc1ccc(C(C)=O)cc1 +Cc1occc1CN(C)c1cc(N2CCCC2CO)ncn1 +O=C(c1nc(-c2ccccc2)nc2c1OCO2)N1CCCC1 +Cn1c(CNC(=O)Nc2cccc3ccccc23)nnc1C1CCC1 +CCS(=O)(=O)c1cccc(NC(=O)C2CC=CC2)c1 +O=C(NCCCNC(=O)c1ccccn1)c1cccnc1 +Cc1ccccc1OCCCC(=O)N1CCCC(n2cncn2)C1 +Cc1ccc(-c2ncco2)cc1NC(=O)Cn1nc(C)c(Cl)c1C +CCC1CN(Cc2ccccc2)CCN1C(=O)CCc1ccco1 +Cc1c(C(=O)NC(CC(C)C)c2nc(-c3nc[nH]n3)no2)cnn1C +COc1ccc(CCC(=O)NCc2ccccc2OC)cc1 +Cc1ccc(C(O)CNC(=O)c2ccccc2C(F)(F)F)o1 +O=C(NCCOc1ccc(F)c(F)c1)NCCC(=O)N1CCCC1 +O=S(=O)(c1ccc(Cl)cc1F)N1CCN(CC2CC2)CC1 +COC(=O)CC1CCCCN1C(=O)Nc1ccc(Cl)cc1 +CCC(C)C(NC(=O)Cn1cncn1)c1nc2ccccc2[nH]1 +N#Cc1ccc(Cn2cnc3cc(F)c(F)cc32)c(F)c1 +COc1ccccc1C(=O)N1CCCC1c1nc(C2CC2)no1 +Cc1nc(C)c(CCC(=O)N(C)CC(=O)NC(C)(C)C)c(=O)[nH]1 +NC(=O)c1csc(C(=O)N2CCN(c3ccccc3O)CC2)c1 +Cc1cc(C(=O)N2CC3CN(Cc4ccncc4)C(=O)C3C2)[nH]n1 +Cc1cccnc1NC(=O)Cc1cccc2cccnc12 +Cc1cc(C)c2c(=O)n(Cc3ccccc3)c(=O)n(C)c2n1 +Cc1ccccc1CNC(=O)Nc1cnn(-c2ccccc2)c1 +N#Cc1ccc(NCc2cc(Br)c3c(c2)OCO3)nc1 +CC(C)C(=O)NC1CCCN(Cc2cnc(N3CCOCC3)nc2)C1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1cccn(C)c1=O +CCC(=O)Nc1nnc(S(=O)(=O)N(CC)Cc2ccco2)s1 +O=C(Nc1ccc(-c2nccs2)cc1)c1ccc(-n2cccn2)cc1 +Cc1occc1-c1nnc(SCC(=O)c2ccc(F)cc2)n1C +CC(CNC(=O)Nc1cccc2ccccc12)Cn1cccn1 +O=C(CN1CCN(CC(F)F)CC1)Nc1cccc2ccccc12 +CNC(=O)c1ccc(-c2ccccc2OCC(C)C)nc1N +COc1cc(C#N)ccc1OC(=O)C(C)Sc1ccccc1 +CC(C)(C(=O)NCC(=O)N1CCCC1)c1ccccc1F +CC(C)N(CC(N)=O)C(=O)Cc1ccc(C(F)(F)F)cc1 +CC(NC(=O)C1CCOC1)c1ccc(S(N)(=O)=O)cc1 +C#Cc1cccc(NC(=O)NCc2ccc(N3CCCCC3=O)cc2)c1 +CCOCCS(=O)(=O)c1ncccc1Br +Cc1cc(C(=O)COC(=O)c2c(F)cccc2Cl)c(C)n1C +Cc1cn(-c2ccccc2Cl)nc1NC(=O)c1ccn(C)c(=O)c1 +CCN(CC)C(=O)CNc1ccc(C)cc1Br +OCc1cccc(OCCc2ccc3c(c2)OCO3)c1 +CCNS(=O)(=O)c1cccnc1Nc1ccc(Cl)c(C)c1 +CCc1onc(C)c1NC(=O)CCc1cccc(OC)c1 +Cn1nnnc1-c1cccc(NC(=O)Cc2ccccc2F)c1 +O=C(CC(c1ccco1)n1cccc1)Nc1ccccc1 +CC(=O)NCC1CCN(C(=O)CCc2ccsc2)CC1 +Cc1nc(NCCc2nc(-c3cccnc3)no2)c2nc(C)oc2n1 +CCn1nc(C)cc1NC(=O)c1cccc(S(C)(=O)=O)c1 +O=C(NCc1ccoc1)c1ccc(-n2cccn2)cc1 +O=C(NCC1CCCCO1)C1Cc2ccccc2N1 +Cc1ccc(CN(CC(=O)NC2CC2)c2ccc(F)cc2)o1 +CC(C)CC(=O)Nc1ccc(NC(=O)c2ccccc2)c(O)c1 +CC(NC(=O)c1ccccc1F)c1ccc(NC(N)=O)cc1 +NC(=O)NC(CC(=O)N1CCOCC1C1CC1)c1cccs1 +N#Cc1ccc2c(c1)CN(Cc1ccc3c(c1)OCO3)C2 +Cc1cc(C)c(C(C#N)CC(=O)N2CCN(C)CC2)c(C)c1 +CCCNC(=O)CNc1ccccc1OC(F)(F)F +CCOC(=O)C1CCN(C(=O)c2cccc3cccnc23)CC1 +CCCS(=O)(=O)c1ccc(C(=O)c2ccccc2)cc1 +Cc1c(C(=O)NCC2(C(N)=O)CCOCC2)sc2ccccc12 +Cc1cc(C)cc(-c2nc(CC(=O)NC3CCCC3)no2)c1 +CN(C)c1ccc(NC(=O)c2cc3ccccc3oc2=O)cn1 +CCCNC(=O)c1ccc(NC(=O)NC(C)C)cc1Cl +O=C(NC1CC(=O)N(CCc2ccc(F)cc2)C1)C1CCCCC1 +COc1c(OC(F)F)ccc2c1C(c1cc[nH]n1)NCC2 +CCc1cnc(C(=O)NC(CO)Cc2c[nH]c3ccccc23)s1 +CCN(Cc1ccccc1)S(=O)(=O)N(C)C(C)c1cccc(O)c1 +CCc1ccc(NC(=O)C2CC(=O)N=C(N3CCOCC3)N2)cc1 +COc1cc(C(=O)NCC(=O)NC(C)(C)C)ccn1 +Cn1cc(C(=O)Nc2ccccc2)c(C(=O)Nc2ccccc2)n1 +CC(=O)N1CCCN(S(=O)(=O)N(C)C(C)C)CC1 +O=C(CNC(=O)c1cc(F)cc(F)c1)NC1CCCC1 +Cc1nc(C(=O)NC2(c3ccc(Cl)cc3)CCC2)cs1 +CCOC(C)c1noc(CNc2cccc(C(=O)NC)c2C)n1 +COC(=O)Nc1cccc(NCc2ccccc2C#N)c1 +N#Cc1ccc(-c2csc(C(C#N)C(=O)CCn3cccn3)n2)cc1 +CC(=O)N1CCc2cc(NC(=O)NC(C)c3ccc(C)o3)ccc21 +Cc1nc(C)c(CC(=O)N2Cc3ccccc3C(O)C2)c(=O)[nH]1 +CC(C)Oc1ccccc1C(C)NC(=O)c1cnccn1 +Cc1ccc(C)c(N2CCN(C(=O)c3cn4ccccc4n3)CC2)c1 +COc1cccc2c1C(c1ccncc1F)NCC2 +CC(=O)N1CC=C(c2ccc(OS(C)(=O)=O)cc2)CC1 +CC(=O)NCc1ccc(S(=O)(=O)Oc2ccc(C)c(C)c2)s1 +COc1cc(-c2nnc3c(C)cccn23)ccc1N +CC1(C)C(NC(=O)c2ccc(Cl)c3cccnc23)C2CCOC21 +Cc1ccc2ncc(C(=O)NCC(C)(C)NS(C)(=O)=O)n2c1 +COc1ccc(F)cc1NC(=O)c1cn(CCC(C)C)nn1 +CN(Cc1cccc(Br)c1)C(=O)c1ccc2[nH]cnc2c1 +Cc1nc(-n2cnnc2)ccc1-c1cc2ccccc2o1 +O=C(NC1CCN(C(=O)c2ccoc2)CC1)c1ccc2ccccc2n1 +CCCCNC(=O)C1CCCN(S(C)(=O)=O)C1 +COC(=O)c1cccn2nc(-c3ccccc3Cl)nc12 +O=C(NCC(O)c1ccc2c(c1)CCO2)C1(c2cccs2)CC1 +COc1ccccc1C(C)NC(=O)c1[nH]nc(C)c1Br +O=C1C(Sc2ncnc3nc[nH]c23)CCN1c1ccccc1 +CC(C)(C)NS(=O)(=O)c1cccc(C(F)(F)F)c1 +O=C(NC1CCN(CC(F)(F)F)C1)N1CCc2ccccc21 +CCC(NS(=O)(=O)c1ccc(Cl)cc1)C(N)=O +CCN1CC(C(=O)N2CCC(C(N)=O)CC2)CC1=O +CSc1ccc(CN(C)C(=O)COc2ccc(F)cc2F)cc1 +Cc1nn(-c2ccccc2)c(CN2CCOC(c3ccco3)C2)c1C#N +COc1c[nH]c(CN2CC3CCC(C2)N(CC2CCC2)C3=O)cc1=O +OCCc1cn(Cc2ccccc2C(F)(F)F)nn1 +Cn1c(=O)c2c(nc(N(CCO)CCO)n2C)n(C)c1=O +Cc1nc(NC(=O)C2CCCO2)sc1C(=O)N(C)C +C=CCOC(=O)c1nn(CC(C)C)c(=O)c2ccccc12 +O=C(CC(c1ccccc1)n1cccc1)N1CCCC1 +O=C1CN(C(=O)CSc2ccccc2Cl)c2ccccc2N1 +CCN(CC1CC1)C(=O)CCNC(=O)c1n[nH]c2ccccc12 +Cc1nc(NCCN2CCOC2=O)c2sccc2n1 +Cc1noc(C)c1CCC(=O)N1CCCC2(CC1)CN(C)C(=O)O2 +COc1ccc(-c2cc(CN(C)C(=O)CC(C)C)no2)c(OC)c1 +O=C(Nc1cccc(C(=O)NC2CC2)c1)c1ccc(-n2ccnc2)nc1 +Cc1ccc(-c2noc(C3CCN(C(=O)c4ccccn4)CC3)n2)cc1 +Nc1cccc(C(O)CCC(=O)NCCc2ccccc2)c1 +CN(CCc1ccc(F)cc1)C(=O)c1ccnc(-n2ccnc2)c1 +Cc1nc(N)nc(C(F)(F)F)c1Br +CNC(=O)c1ccc(C)c(NC(=O)c2cccc(OC(F)F)c2)c1 +Cc1ccc(Cl)cc1C1CCCn2nc(N)nc21 +CCn1c(Cc2ccccc2)nnc1SCC(=O)C1=NC=CC1 +CC(=O)C1CCc2cc(N)c(Br)cc21 +COC1C2CCC1N(C(=O)c1cc3ccccc3o1)CCO2 +COc1ccc(C(=O)NCC2Cc3ccccc3O2)nn1 +Cc1c(C(C)NC(=O)N(CCCCO)C2CC2)oc2ccc(F)cc12 +CCOc1cc(C)c(C(=O)CCC(=O)OC)c(C)c1 +O=C(c1csc(NCc2ccccc2Cl)n1)N1CCOCC1 +NC(=O)C1CCN(C(=O)Cc2ccccc2F)C1 +CCOC(C)c1ccc(-c2nc(C)cc(NC)n2)cc1 +CC(=O)NCCCNC(=O)c1cnn(-c2ccc(F)cc2)c1C +COc1cccc(C(C)NC(=O)COC(=O)c2ccccc2)c1 +CN(C1(C#N)CCCC1)S(=O)(=O)CCc1ccccc1 +CC1CC1C(=O)Nc1cccc(C(=O)NCCNC(=O)C2CC2)c1 +COCC(=O)NCc1cc(=O)oc2cc(F)ccc12 +CCCCc1nnc(SCC(=O)Nc2nccs2)n1N +CC(C)(C)c1nnc(NC(=O)NCc2ccc(F)cc2)s1 +O=C1CC(c2cccs2)c2c(-c3ccccc3)n[nH]c2N1 +CCC(C)NC(=O)CCNC(=O)C12CC3CC(CC(C3)C1)C2 +Cc1cc2c(cc1-c1cn(Cc3cnc4ccccn34)nn1)OCCO2 +Cc1cc(C)nc(SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)n1 +Cc1ccc(-c2ccc(=O)n(C(C)C(=O)NCc3ccccc3)n2)cc1 +COc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(OC)c1 +CCCN1C(=O)CCC2CN(c3cc(OC)nc(N)n3)CCC21 +COc1ccc(C2=CCN(C(=O)c3ccc[nH]c3=O)CC2)cc1 +Cc1noc(C)c1S(=O)(=O)NCCc1ccc(OC(C)C)cc1 +O=C(NC(c1cccs1)C1CC1)c1ccc(-c2ccco2)[nH]c1=O +CCCN(Cc1ccccc1)C(=O)C1Cc2ccccc2C(=O)O1 +Cc1cccc(CNC(=O)Nc2ccc(Br)c(C)n2)n1 +COc1cccc(OC)c1C(=O)c1ccc(OC(F)F)c(N)c1 +Fc1cccc2c1CCNC2C1COc2ccccc2O1 +Cn1c(C(C)(C)C)nc2cc(NC(=O)Nc3cccnc3)ccc21 +Cc1ccc(CNC(=O)c2cccnc2N2CCCC2)s1 +CCCNC(=O)c1nc(N2CCOCC2)c2c(C)cc(C)nc2n1 +CCN(CC)C(=O)c1cc(-c2ccccc2O)on1 +Cc1csc(NC(=O)NC2CCN(c3ccccc3)CC2)n1 +COc1cc(Cl)ccc1C(=O)OCCCNC(C)=O +COc1ccc(OC)c(Nc2nc(C)nc3c2CCC3)c1 +COC(=O)CCN(C(=O)c1cnn2c1CCCC2)c1ccccc1C +COCC(C)NC(=O)Nc1c(C)c(C2CC2)nn1-c1ccccc1 +CCOC(=O)c1[nH]c(C)c(C(=O)Nc2ccc(F)c(Cl)c2)c1C +Fc1ccc(C(F)(F)F)c2c1CCNC2C1CCCO1 +Cc1ccsc1CNc1cccc(C(=O)NCc2cccnc2)c1 +CCOC(=O)CN(C)S(=O)(=O)c1cccc(Cl)c1 +CC12CCC(C(=O)NCC3CCCO3)(CC1O)C2(C)C +Cc1cc(NC(=O)CNc2ccc(C(N)=O)c(F)c2)n(C(C)(C)C)n1 +CC(C)C(=O)Nc1ccc(C(=O)NCCNS(C)(=O)=O)cc1 +C=CCn1c(N)nnc1SCc1cccc(F)c1F +C(#Cc1ccc(C#CCN2CCOCC2)cc1)CN1CCOCC1 +COc1cccc(CCNC(=O)c2n[nH]c3ccccc23)c1 +Cc1cccc(N2CCN(C(=O)c3cccc(F)c3)CC2)c1C +Cc1noc(-c2ccc(S(=O)(=O)NC3CCCC3)o2)c1C +CC(=O)c1ccccc1NC(=O)Cc1coc2cc(C)ccc12 +CC(=O)Nc1ccc(OCc2nc(CC(C)C)no2)cc1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)N(C)Cc1ccco1 +O=C(NCCCOCc1ccccc1)c1cnc2ccccc2n1 +Cc1ccccc1C(=O)N1CCN(CC(F)(F)F)CC1 +N#CC(C(=O)COC1CCCC1)c1nc2ccccc2[nH]1 +CNc1cc(C(=O)N2CCN3CCNC(=O)C3C2)ccn1 +Cc1ccc(F)cc1C(=O)NC(C)(C)CNC(=O)OC(C)(C)C +Cc1ccc2nc(C)c(C(=O)N(CCC#N)Cc3cccnc3)cc2c1 +Cc1ccc(CC(=O)NCC(=O)Nc2nccs2)cc1 +O=C(c1cocn1)N1CCC2(CC(Nc3ncccn3)CCO2)C1 +Cc1ccc(-c2nc(Cn3nc(C)c(C)c(C#N)c3=O)cs2)o1 +COc1ccc2c(ccn2CCC(=O)Nc2cccnc2)c1 +O=C(c1ccccc1)N1CCN(c2ccccc2F)CC1 +CCC(C)NC(=O)c1ccn(-c2ccccc2N)n1 +O=C(Nc1ccncc1)c1cc2c(s1)-c1ccccc1CC2 +COc1ccccc1Oc1ccc(NC(=O)c2ccccn2)cc1 +O=C(NCc1ccc2sccc2c1)C1CCN(C(=O)C2CC2)CC1 +CCOc1cc(C)ccc1NC(=O)C1CCCN1C(=O)C1CC1 +COc1ccc(N2CCN(CCCn3nnnc3C)C(C)C2=O)cc1 +CN(CCc1ccc(F)cc1)C(=O)C1CCN(c2ncccn2)CC1 +COc1ccc(CCC(=O)NCC2CC2C)cc1OC +Cc1ccc(OCC(=O)Nc2nonc2C)c(C)c1 +Cc1cc2c(c(=O)[nH]1)C(=O)OC2=Cc1cccs1 +CCOC(=O)c1cccc(OC(=O)c2ccn(C)c(=O)c2)c1 +O=C1CCN(c2ccccc2S(=O)(=O)C(F)F)CC1 +CC1CC(C)CN(S(=O)(=O)N(C)CC(=O)NC(C)(C)C)C1 +N#CC(C(=O)CCc1ccccc1)c1ccc(C(F)(F)F)cn1 +CC1CC1C(=O)OCC(=O)N1CCN(C(=O)Nc2ccccc2)CC1 +O=C(CNC(=O)c1ccc(Cl)cc1Cl)NCc1ccco1 +CCN(Cc1ccccc1)C(=O)c1nn(C)c2c1COc1ccccc1-2 +CCN(CC)C(=O)CSc1ccc(-c2ccco2)nn1 +Cc1cc(C)c(NC(=O)c2ccc(C)s2)c(C)c1 +CCc1cnc(N2CCC3(CC(Nc4cnccn4)CO3)C2)nc1 +C#CCN1CCN(C(=O)c2cc(S(C)(=O)=O)ccc2Cl)CC1 +CN(CCNC(=O)Cc1ccccn1)S(C)(=O)=O +CC1CCN(C(=O)c2cccc3ncccc23)CC1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)CCCOc1ccccc1 +CN(CC(=O)Nc1ccc(OC(F)(F)F)cc1)c1ncccn1 +CC(C)CC(NC(=O)Nc1cn[nH]c1)C(=O)N(C)C +COC(=O)C1=C(C)C(c2cccs2)NC(=O)N1 +CC(=O)Nc1cccc(C(=O)OCC(=O)Nc2c(C)cccc2C)c1 +COc1ccccc1N1CCN(C(=O)c2ccc(N)nc2)CC1(C)C +Cc1cc(CNC(=O)C2CCN(S(C)(=O)=O)CC2)c(C)o1 +COC(=O)c1ccccc1NC(=O)NC1CCCC1 +O=C(Cc1csc(-c2ccco2)n1)N(Cc1ccncc1)C1CC1 +CC1=C(C(=O)OC(C)C)C(c2ccc(F)cc2)NC(=O)N1 +Cc1nn(C)c(C)c1S(=O)(=O)N(C)C(C)CC#N +CC(C)CNC(=O)c1cccc(NC(=O)c2cccs2)c1 +O=C(Nc1cccnc1)c1c[nH]nc1-c1cccc(Cl)c1 +CCC(C)(NC(=O)c1cccc(OCC(F)F)n1)c1nccs1 +CCCCN1CCc2ccc(NC(=O)C(C)NC(C)=O)cc21 +CC(Cc1ccc2ccccc2c1)NC(=O)c1cnn(C)c1 +CCCc1noc(CNc2ccccc2C(=O)N2CCCCC2)n1 +Cc1cc(CC2COCC2NC(=O)c2snnc2C(C)C)on1 +Cc1csc(-n2nnc(CO)c2-c2cccnc2)n1 +CC(C)n1nnnc1SCC(=O)Nc1ccc2c(c1)OCO2 +Cc1ccccc1-n1ncc(C(=O)NCCCOC2CCCC2)c1C +Cc1ccccc1OCCC(=O)NC(C)c1nnc2n1CCCCC2 +O=C(Cc1ccc[nH]1)NCCCS(=O)(=O)c1ccccc1 +NC(=O)c1cccc(S(=O)(=O)NCCc2ccc(F)cc2)c1 +CC1CC1CNC(=O)Cc1cc2ccccc2[nH]c1=O +Cc1ccc2cccc(OS(=O)(=O)c3ccccc3)c2n1 +Cn1cc(C(=O)NC2CCN(C(=O)C3CCC3)CC2)c2ccccc21 +Cc1cc2ccccc2n2c(=O)n(CC(=O)N3CCCCCC3)nc12 +COC(=O)CSc1nc2c(c(=O)n1C)SCC2 +CCNC(=O)CSc1nnc(-c2cccs2)o1 +O=c1[nH]nc2cc(-c3cccnc3)nc(-c3ccncc3)n12 +O=C(CCCn1c(=O)oc2ccccc21)N1CCOC2CCCCC21 +COCCNC(=O)C1CC(=O)N(c2cnn(CC(C)C)c2)C1 +O=C(NCCOc1ccccc1)c1n[nH]c(=O)c2ccccc12 +CCOc1ccc(CC(=O)NC2(c3nc(C)no3)CCCCC2)cc1 +Cc1nnc2n1CCN(CCC(=O)N1CCCCC1)C2 +O=C1CCc2ccc(C(=O)N3CCCc4ccccc43)nc2N1 +O=C(NCCN1CCOCC1)c1cc2cn(C3CCCC3)cc2s1 +CC1(NC(=O)Nc2cccc(Cn3ccccc3=O)c2)CCOC1 +CCOc1cc(C(=O)NCc2cccnc2)ccc1N +Cc1cc(C)c(NCCn2nc3ccccn3c2=O)c(C)c1 +CC1CC(C)CN(C(=O)C(C)n2nnc(-c3ccccc3)n2)C1 +CCOC(=O)c1ccc(OCC(=O)Nc2sccc2C#N)cc1 +CCOc1ccc(-c2nnc(NC(=O)c3ccco3)o2)cc1OCC +NC(=O)c1ccc(OCC(=O)Nc2ccc3c(c2)OCO3)cc1 +CCn1cc(CN(C(=O)c2cccc3nccnc23)C(C)C)cn1 +CC1CCCCC1NC(=O)C1CCN(C(N)=O)CC1 +Cc1ccc(-c2n[nH]c(-c3cncc(Br)c3)n2)cc1N +Cc1csc(CCNC(C)c2ccc(C)o2)n1 +Cc1ccc(OCCNC(=O)Nc2cc(C)nn2C)cc1 +CN1CCN(C(=O)c2ccsc2)c2cc(F)ccc21 +CCCOC(=O)c1ccc(NC(=O)N(C)C)cc1 +O=c1ccc2cc(S(=O)(=O)NCCC3=CCCCC3)ccc2[nH]1 +FC(F)(F)c1ccc(CN2CCN(c3ncccn3)CC2)cc1 +Cc1ccc2c(c1)CCCN2C(=O)CCNC(=O)OC(C)(C)C +Cc1nnc(SCC(=O)c2ccc(O)cc2O)n1C1CCCCC1 +Cc1cccc(NC(=O)CSc2nnc(C)c(C)c2C#N)c1C +C=CCNC(=O)CCn1c(=O)[nH]c2ccccc2c1=O +Cc1cccc(C)c1NC(=O)c1cccc(S(=O)(=O)NC2CC2)c1 +CC(C)(O)CSc1nc2ccccc2c(=O)n1Cc1ccco1 +COc1ncccc1C(=O)N1CC(c2nc(-c3ccccc3)no2)C1 +CC(=O)c1cccc(NC(=O)c2cnc(N3CCCCC3)nc2C)c1 +COc1ccccc1CC(=O)N1CC(=O)Nc2ccccc21 +CC(=O)Nc1cccc(NC(=O)C(C)CC(N)=O)c1 +O=C(NCCc1ccccc1)c1cncc2cnccc12 +COCCCNC(=O)N1CCCC1c1ccccc1C +O=C(NCCn1ccc(-c2cccs2)n1)c1ccncc1 +O=C(CCn1c(=O)oc2ccccc21)NCc1cccc2ccccc12 +O=C1COC(c2ccc(OC(F)(F)F)cc2)CN1 +CC1=C(C(=O)NCc2cc3ccc(F)cc3[nH]c2=O)C(C)NC(=O)N1 +CC(C)C(=O)NC1CCN(C(=O)Cc2ccc3c(c2)OCCO3)CC1 +COC(=O)CCCN(C)C(=O)Cn1c(C)c(C)sc1=O +CNC(=O)C1CCC(NC(=O)CCCOC)CC1 +CCOC(=O)c1nnsc1NC(=O)NC1CCCCC1 +CCOc1c(O)ccc2c1C(c1ccnnc1)NCC2 +CCCN(C)C(=O)Nc1cc(C(=O)NCC)ccc1C +Cc1ccc(NC(=O)C2CC2)cc1NC(=O)CCn1cncn1 +COCc1nccc(C2CCCN(c3ncnc4sccc34)C2)n1 +CCOC(=O)c1cccc2[nH]c(-c3ccccc3N)nc12 +C=CCN(CC=C)C(=O)CNc1cccc(C#N)c1 +O=C(c1ccccc1)N1CCC(c2cccs2)CC1 +CCOC(=O)c1cc(O)c2c(OC)ccc(OC)c2c1 +CCC(COC)NC(=O)Nc1ccc(Cl)cc1 +CC(O)CC1COCCN1C(=O)NCc1ccc2ccccc2c1 +CN(CCC#N)C(=O)Nc1cccc(N2CCOC2=O)c1 +O=c1[nH]cnc2cc(-c3cc(F)cc(F)c3)ccc12 +Cc1nc(CN2CCN(Cc3ccc(C(C)(C)C)s3)CC2)no1 +CC(C)n1cnnc1C1CCCN(c2cccc(C#N)n2)C1 +Cc1nc(N2CCCC2)c2c(C(=O)NC3CCCCC3)c(C)oc2n1 +CCn1nnc2cc(C(=O)Nc3nc(-c4ccccc4)cs3)ccc21 +CC(=O)c1ccc(OCc2nnc(C(C)C)o2)cc1F +COc1ccc(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)nn1 +COCCCNC(=O)Cc1cc(-c2cccs2)on1 +CCCS(=O)(=O)N1CCCC1C(=O)Nc1ccc(F)cc1OC +CCc1ccc(-c2csc(NC(=O)c3ccn(C)n3)n2)cc1 +Cc1ccc(CC(C)NC(=O)C2CCCN(C(=O)C3CC3)C2)c(C)c1 +COc1ccc(-c2nc(COC(=O)C(C)c3cccs3)no2)cc1 +O=S(=O)(N=c1cccc[nH]1)c1c(F)cc(F)cc1Br +CCCC(CCC)C(=O)Nc1nnc(S(N)(=O)=O)s1 +Cc1ccnc(SCc2cc(O)n(-c3nc4ccccc4[nH]3)n2)n1 +CCc1nnc(-c2cn(CC(=O)NC)c3ccccc23)o1 +CC(C)CCNC(=O)c1ccccc1SCC(=O)N(C)C +O=C(Cc1cccc(O)c1)N1CCC2(CC1)OCCO2 +CC(C)Oc1ccc(S(=O)(=O)NC2(C#N)CCCC2)cc1 +Cn1cnnc1SCC(=O)Nc1ccc(N)cc1Cl +CNC(=O)c1ccc(CNC(=O)Cc2ccc(C)nc2)cc1 +CCOC(=O)c1ccc(S(=O)(=O)N=c2[nH]cccc2C)cc1 +Cc1csc(NC(=O)CSc2nnc(-c3ccccc3C)o2)n1 +COc1ccccc1C(=O)NC(C(=O)Nc1cc(C)ccn1)C(C)C +CC(C)(C)CC(C)(C)NC(=O)c1cc(F)ccc1N +C#CCN1CCN(C(=O)NC2CCN(c3cccs3)CC2)CC1 +CCN(CC)C(=O)c1cc(Cl)c2c(c1)OCCCO2 +Cn1c(C(=O)Nc2cccc(C(N)=O)c2)cc2sccc21 +CCn1nc(C)cc1C(=O)NCC(=O)Nc1cccc(C(=O)OC)c1 +O=C(NCCNc1ccc(Nc2ccccn2)nn1)C1CCCO1 +CN(CC1CCN(c2ccccc2)C1)C(=O)CCn1cncn1 +CCC(CO)NS(=O)(=O)c1ccc(C)c(N)c1 +Cc1cc(N2CCCC2=O)cc(C)c1S(=O)(=O)N1CCCCC1 +CN(CCO)C(=O)c1ccc(Br)cc1O +Cn1nc(CNC(=O)c2ccc(F)cc2)c2ccccc21 +CCCC1C=CCN1C(=O)c1ccc(-c2ccccc2)[nH]c1=O +COc1ccccc1CN(C)C(=O)Cn1cnc2ccccc21 +O=C(NCCc1c[nH]c2ccc(F)cc12)c1cc2ccccc2o1 +CC(=O)N1CCc2c(nc(-c3cccnc3)nc2NCCCCO)C1 +CC1(CNC(=O)c2cc(-c3cccc(F)c3)no2)COC1 +Cc1[nH]c2ccccc2c1C(=O)COc1ccc(C(N)=O)cc1 +CC(Sc1ncn[nH]1)C(=O)NCc1ccc(OC(F)(F)F)cc1 +COCCCNC(=O)CN(C)C(=O)c1c[nH]c2ccccc12 +O=C(CCC(=O)c1ccc2c(c1)CCC2)Nc1ccc2c(c1)C(=O)NC2 +CC(=O)Nc1cc(NC(C)=O)c2ccccc2c1O +CCOc1cc2c(c(Cl)c1OC)C(CN(C)C)NCC2 +CC(C)COc1cncc(N2CCN(Cc3ccon3)CC2)n1 +COc1cc(CNC(=O)CC2C=CCC2)ccc1O +OCc1cc(-c2ccc(F)c(F)c2)oc1C1CC1 +Cc1cc(OCC(=O)N2CCCC2C(N)=O)c2c(C)cc(=O)oc2c1 +CCNc1cc(-c2cccc(C(F)(F)F)c2)n[nH]1 +Nc1nccnc1C(=O)N1CCN(C(=O)c2cccc(F)c2)CC1 +CCN(CC)C(=O)CC1Sc2ncccc2N(CC)C1=O +CCOC(=O)c1ccc(N(C)CC(C)C#N)c(N)c1 +O=C(c1cccc(F)c1)N(Cc1ccc(F)cc1)C1CC1 +COc1cc2c(cc1CNC(C)C(=O)NC1CCCC1)CCC2 +CCc1ccccc1CC1Oc2cc(N)ccc2N(CCO)C1=O +COc1ccccc1C(=O)N(C)Cc1nnc2ccccn12 +NC(=O)c1csc(C(=O)NC2(c3ccc(Cl)cc3)CCC2)c1 +O=C1OC(C(=O)NCc2ccccc2F)Cc2ccccc21 +CC(CNC(=O)NCC(=O)N1CCCC1)N1CCOCC1 +Cc1nc(C(C)(C)NC(=O)c2ncoc2-c2cccs2)no1 +Cc1cccc(CSc2nnc(-n3nc(C)cc3C)n2N)c1 +Cc1ccc(NC(=O)Cn2c(C)cc(=O)c3cccc(C)c32)cc1 +CC(C)CCN1CCN2C(=O)C(CC(C)C)NC(=O)C2C1 +Cc1cc(F)ccc1C(=O)N1CCC(n2ccnn2)CC1 +CC(Oc1ccccc1F)C(=O)NCc1ccc2c(c1)OCO2 +CC1CCCCN1C(=O)c1ccc(CNc2ncccn2)cc1 +CCCCNC(=O)CCc1nc(-c2ccccc2)no1 +N#Cc1c(F)cccc1N1CCCN(C(=O)c2ccsc2)CC1 +CCc1c(C(=O)Nc2cc(NC(C)=O)ccc2C)[nH]c(C)c1C(C)=O +COCCCNc1ncnc(Nc2nc3c(C)cccc3s2)c1N +C=CCNC(=O)Nc1cccc(Cl)c1N(C)C +C=C(C)COc1ccc(C2CC(=O)Oc3cc(C)[nH]c(=O)c32)cc1 +COc1ccc(OC)c(-c2cc(CO)c(C(F)(F)F)o2)c1 +CC(=O)Nc1ccc(NCCC(O)c2ccc(C)cc2)cc1 +O=S(=O)(NC1CCc2ccccc21)c1c[nH]c2ncccc12 +CC(=O)c1c(N)c(-c2cccc(Br)c2)n(C)c1C +CCc1cc2c(s1)SCC(=O)N2CC(=O)NCCCOC +CCN(CC)S(=O)(=O)N(C)Cc1ccccc1Cl +CCCS(=O)(=O)N1CC(S(=O)(=O)c2ccc(F)cc2)C1 +CC(NC(=O)OC(C)(C)C)C(=O)NCc1cnn(C)c1 +CCCCNC(=O)c1ccc(CN2C(=O)COc3ccccc32)o1 +COc1ccc(NC(=O)N2CCc3c(C(=O)N(C)C)cccc32)cc1 +NC(=O)CCCNC(=O)CCc1ccc(Cl)cc1Cl +CN(Cc1ccccc1)c1ncnc(NC(C)(C)C)c1N +Cn1ncc2cnn(CC(O)COCc3ccccc3Cl)c2c1=O +CCn1c(-c2cc(NC(=O)C(C)C)[nH]n2)cc2ccccc21 +CCC(C)(C#N)NC(=O)c1nnn(-c2ccc3ncccc3c2)c1C +CCOc1ccc2[nH]c(=O)c(CN3CCC(=O)NCC3C)cc2c1 +COc1c(CNCc2ccnc(OC3CCCCC3)c2)c(C)nn1C +CNC(C#N)COc1ccccc1Br +c1cc(Cn2nc(-c3ccncc3)c3c2CCNC3)ccn1 +CNC(=O)c1cc(C)ccc1NC(=O)C1CCOCC1 +CC1CC1COC(=O)c1ccc(CCNC(N)=O)cc1 +Cc1cccnc1NC(=O)NC1CCCOc2ccccc21 +CCCc1c(C)nn(-c2nc3ccccc3o2)c1O +CC(=O)Nc1ccc2c(c1)N(C(C)=O)c1ccccc1CC2 +Cc1ccc(C(=O)CSc2nnnn2C2CC2)c(C)c1 +CCNC(=O)c1cccc(NC(=O)c2cc3ccccc3o2)c1 +CCC(C)CNC(=O)c1cc2cc(N)ccc2s1 +Cc1ccc(C(=O)Nc2nnc(C3CCCCC3)o2)cc1 +CNC(=O)NC(C)(C)C(=O)NCC(=O)Nc1nccs1 +CCCNC(=O)C(C)N1CCc2ccc(Cl)cc2C1 +CCOCCCNC(=O)c1ccc(-n2cnc3cccnc32)cc1 +Cc1cccc(NC(=O)c2ccc3c(=O)n4c(nc3c2)CCC4)c1 +COc1cccc(-c2cc(Cn3cc(-c4nccs4)nn3)on2)c1 +NC(=O)c1nn(-c2ccccc2F)c2c1C(=O)CCC2 +CC(=O)Nc1ccc(NC(=O)C(C)Nc2cccc(CO)c2)cc1 +CCC(C)Oc1c(Br)cc(CO)cc1OC +COc1cccc(NC(=O)CN(c2ccccc2)S(C)(=O)=O)c1 +CCC(C)NC(=O)c1ccc(NC(=O)c2cnccn2)cc1 +CC(C)(C)Oc1ccc(C(=O)NCC2CN3CCCCC3CO2)cc1 +CCCC(=O)Nc1ccc(-n2c(C)nc3ccccc3c2=O)cc1 +COc1ccc(CNC(=O)Nc2cccc(Cl)c2OC)cc1O +N#Cc1ccc(N2CCCC(C(=O)N3CCOCC3)C2)nc1 +Cc1nc(-c2ccc(S(=O)(=O)NCc3ccco3)cc2)co1 +CCCNC(=O)C(C)N1CCN(C(=O)Cc2ccccc2C)CC1 +CC(C)NC(=O)COC(=O)c1ccc(N(C)C)cc1F +CC(C)NC(=O)c1nnn(-c2cccc(F)c2)c1C1CC1 +COc1ccc(C(NC(=O)c2ccc3nc(C)cn3c2)C2CC2)cc1 +CNC(=O)C(C)n1cc(C)sc1=NC(=O)c1ccc(C)cc1 +CN(Cc1noc2c1CCCC2)C(=O)c1cc(=O)n(C)c(=O)n1C +Nc1ccc(Cl)c(C(=O)NCc2ccco2)c1 +Cc1cc(C)n(CC2CCCCN2C(=O)C2Cc3ccccc3O2)n1 +Cc1ccc(-n2nc(C)c3c(C)cc(=O)oc32)cc1 +CC(C)(C)NC(=O)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +CCCNC(=O)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 +CCc1c(C(=O)OCC2CCC(=O)N2)cnn1-c1ccccc1 +Cc1csc(C2(NS(=O)(=O)c3ccccc3F)CCCC2)n1 +COC(=O)C(C)Sc1nc(-c2ccc(OC)cc2)n[nH]1 +NS(=O)(=O)c1ccc(CNC(=O)CCOc2ccccc2)cc1 +CCc1ccc(S(=O)(=O)N2CCC3(CC2)OCCCO3)cc1 +COc1ccc(S(=O)(=O)N2CCNCC2)cc1C(C)(C)C +CN(C)C(=O)N1CCN(C(=O)c2cnc(-c3ccncc3)nc2)CC1 +Cc1ccccc1-c1nnn(CC(=O)NC2CC2)n1 +Cc1nc(SCC(=O)NC2CCCC2)[nH]c(=O)c1C +C#CCOC(=O)C1CC(=O)N(c2ccc(Br)cc2)C1 +COc1ccc2[nH]c3c(=O)n(Cc4ccco4)cnc3c2c1 +O=C(NCCN1CCCc2ccccc21)c1cccs1 +COc1ccc(S(=O)(=O)N(C)CCC#N)c(OC)c1 +CCC(C)NC(=O)Nc1ccc(N(C)C(C)=O)cc1 +CC(Cc1ccccc1F)NC(=O)c1cccnc1OCC(F)F +Cc1ccccc1C(=O)NCCN(C)c1ccccc1 +Cn1cc(-c2[nH]c(C3CCCCC3)nc2C#N)cn1 +Cc1ccccc1C1CC1C(=O)NC1CCCCC1C(N)=O +CCOCCCC(=O)Nc1nc(C(F)(F)F)cs1 +CSc1ccccc1C(=O)NCc1cc(-c2ccccn2)n(C)n1 +COc1ccc(Br)cc1S(=O)(=O)NCCCO +C=CCn1nnsc1=NCC(=O)Nc1ccc(OC)cc1 +O=C(C1COc2ccccc21)N(CC(F)(F)F)C1CCCOC1 +CCc1cc(=O)oc2c(C)c3occc(=O)c3cc12 +COCCOc1ccccc1C(=O)N1CCc2cc(F)ccc2C1 +CCCNC(=O)c1cccc(NCc2nc(C)cs2)c1 +CSc1ccc(CN(CCO)C(=O)c2ccco2)cc1 +O=C(CNc1ccc(F)cc1)NCc1ccccc1 +Cc1ccc(C(=O)NCC2(O)CCOCC2)cc1Br +CC(O)CN(CC(C)O)C(=O)c1ccc2c(c1)OCO2 +COc1ccc(C(=O)NCc2cc(OC)c(OC)cc2Cl)cc1 +COC(=O)c1ccccc1Oc1nc(OC)cc(OC)n1 +COc1cc(OC)c(OC)cc1CNc1ccc(NC(C)=O)cc1 +Cc1ccc(NC(=O)Nc2ccc(-n3cnnn3)c(C)c2)cc1 +Cc1cnc(COC(=O)c2ccccc2OC2CCC2)cn1 +Nc1c(-c2cccnc2)nnn1-c1ccccc1F +CCCc1noc(CN2CCN(C(C)C(=O)N3CCCC3)CC2)n1 +CCOCCOCC(=O)NC1CC2CCC1(C)C2(C)C +O=C(NCc1ccco1)Nc1cccc2cnccc12 +Cc1cc(=O)c2cccc(F)c2n1CC(=O)NCc1ccco1 +COc1ccccc1NC(=O)NCC(O)COc1ccc(F)cc1 +CC1CCCC(Nc2ccnc(C(=O)N(C)C)c2)C1 +Brc1ccc(CNc2ccon2)cc1 +Cc1nc(C)c(CC(=O)N(C)CCOc2ccccc2C)c(=O)[nH]1 +CCCC(=O)Nc1cccc(NC(=O)c2cnn(CC)c2)c1 +Fc1cccc(-c2nnc(COc3ccccc3-c3nc[nH]n3)o2)c1 +COCCC(=O)N1CCC(NS(C)(=O)=O)C1Cc1ccccc1 +CCOC(=O)N1CCC(Oc2ncccc2Cl)CC1 +CCn1c(C)cc(C(=O)COc2ccc(C#N)cc2OC)c1C +COCc1csc(NC(=O)NCCc2nc(C)c(C)s2)n1 +C=CCC(CC=C)C(=O)N(C)Cc1c(C)nc2sc(C)cn12 +Cc1cc(C)c2c(NCCc3noc(C4CCCC4)n3)ncnc2n1 +CC(C)(CNC(=O)c1ccc(=O)[nH]c1)c1ccccc1 +Cc1cc(C)cc(NC(=O)c2cccc(S(C)(=O)=O)c2)c1 +CC(C)c1cc(C(=O)N(CC(N)=O)C2CCCC2)nn1C(C)(C)C +CCOc1ccccc1NCc1noc(-c2cccs2)n1 +CCCc1nn(C(=O)c2ccco2)cc1C(=O)OCC +c1ccc(CN(Cc2cccc3cnccc23)CC2CCCO2)nc1 +CC(C)(C)C(=O)NC(n1ccc(=O)[nH]c1=O)C(Cl)(Cl)Cl +Cc1cnn(CC2CCCN2C(=O)C2CCOC2)c1 +CCn1nnnc1-c1cccc(C(=O)NCCc2ccccc2F)c1 +Cc1nn(C)c(C)c1NS(=O)(=O)Cc1ccccc1 +COC(=O)C1CCN(C(=O)c2cc3cc(C)ccc3o2)c2ccccc21 +Cc1cccn2cc(CSc3nc4sccc4c(=O)n3C)nc12 +Cn1cnc(CNC(=O)N2CCCC2C(C#N)c2ccccc2)n1 +CN1CC(c2ccccc2)C2(CCN(Cc3cccs3)CC2)C1=O +Cc1cccc(CCNC(=O)NCc2nc(C)cs2)c1 +Cc1noc(C)c1S(=O)(=O)N1CCCC1c1cc[nH]n1 +CN(C)c1ccc(-c2nc(N)nc3[nH]cnc23)cc1 +CC(=O)Oc1ccc(C(=O)Nc2cc(C)ccc2C)cc1 +CCc1nn2c(CO)c(-c3ccc(F)cc3)nc2s1 +COC(=O)C(c1ccccc1)N1CCNc2ccccc21 +COCc1ccc(C(=O)Nc2ccccc2N2CCOCC2)cc1 +CCOC(=O)C(Cc1c[nH]cn1)NC(=O)c1cc2ccccc2n1C +CNC(=O)c1ccc(Cn2c(-c3cccs3)noc2=O)cc1 +CC(C)Cn1nccc1NC(=O)C(C)(C)Oc1ccc(F)cc1 +CCn1ncc(CNC(=O)c2nn(C)cc2N)c1C +Cc1n[nH]c(-c2cccc(CNC(=O)CNC(=O)OC(C)(C)C)c2)n1 +COc1ccc(CC(=O)NCc2ccc3c(c2)OCCO3)cc1 +Cc1ccc(-c2nc(C(=O)Nc3cccnc3)cs2)cc1 +COc1ccc(CC2C(=O)Nc3c(C)cccc32)cc1 +CCOC(=O)C(NC(C)C)c1ccc(Br)cc1 +CC(=O)Nc1cc(NC(=O)NCc2ccccc2)ccc1F +O=C(c1ccc2c(c1)OCO2)N(Cc1ccco1)Cc1ccco1 +CCCc1cc(NCCCc2nnc3ccccn23)n2nccc2n1 +C=C(C)COc1ccc(C(=O)N(C)C(C)Cc2ccccn2)cc1 +O=C(NCC1CC1)C1CC2CN(C(=O)NC3CCCC3)CC1O2 +O=C(Nc1ccc2c(c1)OCCO2)c1cc(-c2ccccn2)[nH]n1 +O=C(Cn1ccc(C(F)(F)F)n1)Nc1cccc(C(F)(F)F)n1 +Cc1n[nH]cc1NS(=O)(=O)c1ccc(F)c(Br)c1 +O=C(NCCCc1c[nH]c2ccccc12)c1ccc(-n2ccnn2)cc1 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccc(C)cc2)cc1 +COc1ccc(CC(C#N)C(=O)NC(C)(C)C)cc1 +O=C(Cc1ccccc1)Nc1cccc2ncccc12 +COCc1cccc(CNC(=O)N(Cc2ccc(C)o2)C(C)C)c1 +COc1ccccc1NC(=O)N(C)CCc1ccccn1 +O=C(NC1CCCC(O)C1)c1cc(-c2ccccc2)on1 +CC(=O)N1CCOCC2(C1)CN(C(=O)c1ccsc1)CCO2 +COc1ccccc1OC1CN(C(=O)CNS(C)(=O)=O)C1 +COc1ccc(NC(=O)c2nnn(-c3ccccc3)c2C)c(OC)c1 +CCNC(=O)CNC(=O)c1ccc(O)c(Cl)c1 +CCn1cc(NS(=O)(=O)c2ccc(Br)cc2N)cn1 +OC(COc1ccccc1F)CN1CCN(c2ccccc2)CC1 +O=C(CSc1nccc(=O)[nH]1)Nc1ccc(F)c(F)c1 +Cc1ccc(C)c(-n2ccnc2S(=O)(=O)CC2CCCO2)c1 +CN(CCCNC(=O)c1nc2ccccc2c(=O)[nH]1)c1ccccc1 +Cc1ccc(F)cc1C(=O)N1CCCC(c2ccn[nH]2)C1 +O=S1(=O)N=CN(Cc2ccccc2)c2ccccc21 +CC(C)c1nn(-c2ccccc2)c2c1C(=O)CCC2 +CCc1oc(C(=O)Nc2cc(C(N)=O)ccc2N(C)C)cc1C +COCCOc1ccccc1NC(=O)c1cc(=O)[nH]c2ccccc12 +COC(=O)c1ccccc1NC(=O)C(C)Oc1ccccc1 +O=C(OCC1C(CO)C1(Cl)Cl)c1ccccc1F +CCC(CC)NC(=O)NCC(=O)Nc1ccc(Cl)cc1 +CCc1c(C(=O)OCCN2CCCC2=O)cnn1-c1ccccc1 +O=C(CSc1nnc2n1CCCCC2)Nc1ccccc1 +CC(C)CNC(=O)c1cc2cc(Cl)ccc2o1 +Cc1nc(CC(=O)N2CCCCC2Cn2cccn2)cs1 +COc1ccc(NC(=O)CCCn2cnc3ccccc3c2=O)cc1 +C=CCNC(=O)Nc1cccc(N2CCCS2(=O)=O)c1 +CC(NC(=O)CN1CCn2c(nn(C)c2=O)C1)c1ccccc1 +CCOCCCNC(=O)CN1CCSc2ccccc21 +CCC(C)(NCc1ccno1)c1nc(C)cs1 +CC(C)NC(=O)c1cnn2c1CN(C(=O)c1ccccc1)CC2 +C=CCNC(=O)C(C)Sc1nc(NC)c2ccccc2n1 +Cc1cc(C(=O)Nc2cc(-c3ccoc3)nn2-c2ccccc2)on1 +CCc1nnc(NC(=O)N2CCCC2C2CCCCC2)s1 +Cc1cc(C2CCCN2C(=O)c2cc(C(F)(F)F)nn2C)on1 +COc1ccc(CNC(=O)C(Oc2ccccc2C#N)C(C)C)cn1 +Cc1nc(C)c(C2NCCc3ccc(O)c(Cl)c32)s1 +CCc1ccc(CNC(=O)CS(=O)(=O)c2cccc(F)c2)s1 +CCC(C)n1ncc(C(=O)NCC2CN(C3CC3)CCO2)c1C1CC1 +Cc1cc(C(C#N)C(=O)NCc2ccc3c(c2)OCO3)nc(C)n1 +COc1cc(NC(=O)Nc2cccs2)ccc1N1CCCC1=O +CC(C)n1nnc(CO)c1CCC1CCCCC1 +CC1CN(C(=O)CS(=O)(=O)c2ccccn2)CC(C)O1 +CC(NC(=O)NCc1cccnc1)C(=O)NCc1ccccc1 +CC(C)COc1ccc(-c2cc(C#N)c(N)[nH]2)cc1 +Cc1ccc(SCCC(=O)NCc2cn[nH]c2)cc1C +N#Cc1ccc(OCc2cccc3cccnc23)cc1 +Cc1sc2nc(CN(C)CCC#N)nc(N)c2c1C +CNc1nc(-c2cnc(-c3ccccn3)s2)cs1 +Cn1c(N)c(C(=O)Cn2cnnc2C#N)c(=O)n(C)c1=O +CCOC(=O)CC(C)CNC(=O)c1ccc(Br)cc1F +CC(C)CCn1ncc(-c2cccc(F)c2)c(C#N)c1=O +Cn1cnnc1C1CCN(C(=O)Cc2cccc(OCC#N)c2)CC1 +COC(=O)c1ccc(C)c(S(=O)(=O)NCCc2cccnc2)c1 +O=C(NCc1cccnc1OCc1ccccc1)c1ccc[nH]c1=O +O=C(NCC1CCCO1)c1cccc(S(=O)(=O)NC2CC2)c1 +COC(=O)C1CCN(Cc2nc3ccc(C)cc3[nH]2)CC1 +O=C(CCC(=O)Nc1cccc(F)c1F)Nc1nccs1 +COc1ccsc1C(=O)N1CCN(CC(O)c2ccccc2)CC1 +CC(C#N)(NC(=O)CSc1nc2ccccc2[nH]1)C1CC1 +CCSc1nc2n(n1)CC(C(=O)Nc1ccccc1C)=C(C)N2 +c1ccc(-c2cc(SCCN3CCOCC3)n3ncnc3n2)cc1 +O=C(NCc1ccccc1OCc1ccccc1)c1csnn1 +N#Cc1c(-c2ccco2)c2c([nH]c1=O)-c1ccccc1CC2 +Cc1nc(-n2nnc(CO)c2COc2ccccc2)sc1C +CC(=O)c1cn(CCC(=O)NCc2ccncc2)c2ccccc12 +CCCn1nccc1NC(=O)c1cc(Br)c[nH]1 +COc1ccc(-n2cnnc2SCC(=O)NCC(F)(F)F)cc1 +Cc1ncc(C(=O)NC2(c3ccccc3F)CCCC2)c(C)n1 +Cc1n[nH]cc1CNC(=O)Cn1cnc2ccccc21 +CCCNC(=O)c1ccc(OCc2cn3ccccc3n2)cc1 +Cc1cc(NC(=O)C(C)N2CCOC(c3ccc(F)cc3)C2)on1 +Cn1ncc2c(NCCCO)nc(N3CCCC3)nc21 +CCc1nc(CNC(=O)NCc2ccsc2)cs1 +C=CCOCC1CC2OCCN(Cc3ccc(C)s3)C2C1 +CC(Cc1cccc(N)c1)c1nc2ccccc2[nH]1 +O=C(NCc1ccccc1)N1CCN(Cc2cnc3ccccn23)CC1 +Oc1ccc(CC2NCCc3cc(Cl)c(O)cc32)cc1 +O=C(CCOC1CCOCC1)Nc1ccc2scnc2c1 +CNC(=O)c1cccc(OC(=O)COc2ccc(F)c(Cl)c2)c1 +CN(Cc1cc(Br)cs1)C(=O)c1ccno1 +O=C(c1cn2c(n1)CCC(c1cc(F)ccc1F)C2)N1CCOCC1 +O=C(Cn1cnc(C2CCC2)cc1=O)NCc1ccccc1 +CCn1cnnc1CNC(=O)c1cc(C)n(Cc2cccs2)c1C +CCCOc1c(CNc2cccc(O)c2)cccc1OC +COCC(=O)Nc1nc(-c2c[nH]c3ncccc23)c(C)s1 +COc1ccc(C2CCN(C(=O)NCC(=O)N3CCCCC3)C2)cc1 +O=C(Nc1cc(C2CCOCC2)[nH]n1)c1cc(F)cc2cccnc12 +O=C(CNC(=O)c1cccc(F)c1)NC1CCc2c(F)cccc21 +COC(=O)C1(C(F)(F)F)N=C2C=CC=CN2C(c2ccco2)=N1 +CCN(CC)C(=O)C(C)n1c(C)cc(C)nc1=O +COc1cc(NCCCc2ccccn2)c(OC)cc1Cl +O=C(c1ccc(N2CCOCC2)nc1)N1CCc2ccccc2C1 +CC(C)S(=O)(=O)NCCCN(C)c1ccccc1F +O=C(c1ccco1)N1CCCC12CCN(S(=O)(=O)C1CC1)CC2 +CCN(CC)C(=O)Nc1cccc(NC(=O)c2cccs2)c1 +Cc1ccccc1C(=O)N1CCC2(CC1)CC(c1cnn(C)c1)CO2 +CC1Oc2ccc(NC(=O)C3CC3C)cc2NC1=O +O=C(CCNC(=O)Nc1nncs1)NC1CCCC1 +CCn1c(SCc2cc(=O)n3c(C)csc3n2)nnc1C1CC1 +CCC(=O)N1CCc2cc(C(=O)Nc3cccc(OC)c3)ccc21 +CCc1ncc(C(=O)N2CCCC(OCc3ccccc3)C2)cn1 +CC(C)c1cccc(C(C)C)c1NC(=O)c1ccccc1N +CC(C)C(=O)Nc1ccc(C(=O)OCC(F)(F)F)cc1 +COc1ncccc1C(=O)Nc1ccc(NC(=O)C2CC2)nc1 +CCCOc1ccc(CN2CCC3(C2)OCCO3)cc1OCC +CCOCCNS(=O)(=O)c1cccc(-n2cnnn2)c1 +CC(=O)N1CCCc2ccc(NC(=O)c3ccccc3F)cc21 +COc1ccc(CNC(=O)c2ccc(C#N)cc2)cc1OC +COCC(=O)N1CCC2(COCc3cnc(N(C)C)nc32)C1 +CCc1ccc(O)c(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)c1 +CCCC(C)NC(=O)C1CC(=O)N(c2ccc(F)cc2)C1 +CC(C)(C)OC(=O)NCc1ccnc(-n2ccnc2)c1 +CC(=O)Nc1ccc2c(c1)C(c1ccco1)NCC2 +c1cncc(COc2ccccc2CN2CCOC3(CCC3)C2)c1 +COCCNC(=O)Nc1ccc(Oc2ccc(C)cc2)nc1 +Nc1cc(C(=O)NC2CCCCC2O)cc(Cl)c1Cl +Cc1ccc(C(=O)NCC2(C(N)=O)CCOCC2)c(O)c1 +Cc1cc(NC(=O)c2ccc3ccccc3c2)nn1C +COc1ccccc1N1CCN(c2cc(C)nc3ncnn23)CC1 +Cc1ncccc1Oc1cncc(C2CCCN2S(C)(=O)=O)n1 +CC(C)N1CCN(C(=O)Cc2ccccc2)CC1C(N)=O +Cc1noc(-c2ccnc(-c3ccc(C(N)=O)cc3)c2)n1 +OCCSc1nnc(-c2c[nH]c3ccccc23)n1CC1CCCO1 +CC(C)(C)C(=O)NCCNC(=O)c1nonc1N +Cc1n[nH]c2ncc(C(=O)NCCCN3CCOCC3)cc12 +CCC(CCO)NS(=O)(=O)c1ccc(Br)cn1 +COCC(C)(NC(=O)c1ncn(-c2ccccc2)n1)c1ccccc1 +O=C(COC(=O)c1cc(Cl)ccc1Cl)C1=NC=CC1 +COc1ccc2c(ccn2CC(=O)Nc2nnc(CC(C)C)s2)c1 +Cc1nc(NC(C)c2ccsc2)c2cnn(C)c2n1 +O=C(Nc1ccc(F)c(S(=O)(=O)NC2CC2)c1)c1ccnnc1 +O=C(Nc1ccc2c(c1)COC2)c1cccc(OCc2cccnc2)c1 +CCOC(=O)c1cccc2cnn(-c3ncccc3C#N)c12 +Brc1csc(CNCCc2nnc3ccccn23)c1 +COc1cccc(-c2cnn(C)c(=O)c2CC#N)c1 +COc1ncccc1C(=O)N(C)CC(=O)NC(C)C +CCN(C)c1ccccc1NC(=O)C1CCCN(C(=O)C2CC2)C1 +COc1ccc(OC)c(CNC(=O)Nc2cn[nH]c2)c1 +Cc1cc(=O)[nH]c2cc(NC(=O)c3ccncc3)ccc12 +O=C1C(NCc2cccc(F)c2)CCCN1Cc1ccccc1 +CN(Cc1cc(-c2ccccc2)no1)C(=O)c1ncc(F)cc1F +CCOc1ccc(-c2nnc(-c3nonc3N)o2)cc1 +CN(C(=O)c1sccc1Br)C1CCCC1 +NCC(=O)c1ccc(-c2ccc3c(c2)OCCO3)s1 +CCCNC(=O)c1cccc(NC(=O)c2nnc(CC(C)C)s2)c1 +COc1cccc(-c2nnc3c(-c4ccccc4)cnn3c2N)c1 +CCOC(=O)C1CC2CC(O)CCC2CN1C(=O)OC +COc1ccc(COC(=O)CN(C)C(=O)c2cccs2)cc1 +Cc1nc2cc(NC(=O)Nc3ccccc3F)ccc2n1C +Cc1ccccc1CNC(=O)CSc1nc2ccccc2o1 +O=C(NCc1ccon1)Nc1ccc(OCc2ccco2)c(Cl)c1 +O=C(NCc1ccccc1Cn1cncn1)C1CC2CCC1C2 +O=S(=O)(c1ccc(Cl)c(Cl)c1)C(F)F +OCCc1cc(C2CCCN(c3ncccn3)C2)n[nH]1 +Cc1nnnn1-c1cccc(NC(=O)N(C)C2CCCCC2)c1 +CCS(=O)(=O)N1CCC2(CN(c3cc(OC)ncn3)C2)C1 +Cc1nc(NC(=O)C(C)(C)c2ccccc2)sc1SCC(N)=O +Cn1cc(NC(=O)CN2CCOC(Cc3ccccc3)C2)cn1 +Cc1ccccc1C(C)NC(=O)NCc1cccnc1 +Cc1cc(C)nc(N2CCCC(C(=O)N(C)C)C2)n1 +CC(C)NC(=O)Nc1ccccc1CC(=O)N(C)C +CC(C)C1Oc2ccc(Br)cc2NC1=O +CCN(CCC#N)C(=O)CNc1cc(F)c(F)cc1NC(C)=O +CN(C(=O)CSc1ccc(O)cc1)C(C)(C)C#N +COc1cc(CNC(=O)NCCC2CC3CCC2C3)ccn1 +CC(NC(=O)c1cncn1-c1ccccc1)c1ccc2c(c1)CC(=O)N2 +CCc1nnc(CN(CC)C(=O)CN2C(=O)COc3cccnc32)o1 +O=C(CSc1ccc2c(c1)OCCCO2)c1ccccc1 +COC(=O)C(C)N1CCc2cc3c(cc2C1)OCO3 +NS(=O)(=O)c1ccc(C(=O)NCC2(c3ccccc3)CC2)o1 +O=C(Cn1nc(-c2ccco2)ccc1=O)NCCc1ccccn1 +COc1cc(N)c(CN(C)c2ccccc2)cc1OC +CC(=O)NCc1ccc(-c2csc(NC(=O)C3CCCCC3)n2)o1 +N#Cc1cccc(S(=O)(=O)N(Cc2ccccc2F)C2CC2)c1 +Cc1[nH]c2cc(-c3ccccn3)nn2c(=O)c1CCC#N +COC(=O)NCC(=O)NC(C)Cc1cccc(Cl)c1 +Cc1ccc(NC(=O)c2cccn2Cc2noc(C3CC3)n2)cc1F +Cc1ccc2ncc(CN3CCN(C(=O)c4cc(C)no4)CC3)n2c1 +Cc1c(C(=O)N2CCCC2CC(C)(C)C)cnn1-c1ccncc1 +COc1cc(NC(=O)COc2ccccc2)ccc1N1CCCC1=O +Cc1cc(C(=O)NCc2nncn2C)c(C)n1-c1nccs1 +COCc1cccc(CNS(=O)(=O)c2cccc(Cl)c2C)c1 +COc1ccc(NC(=O)C(C)Oc2cccc(C)c2)c(N)c1 +COC(=O)c1occc1Cn1cc(Cl)c(=O)[nH]c1=O +COC(=O)c1sccc1NC(=O)C#Cc1ccccc1 +CCN(C(=O)c1cc(=O)[nH]c2ccccc12)C1CCOCC1 +O=C(Cc1ccsc1)NCCc1cccc2cccnc12 +Oc1ccc(CNCCc2ccc(F)cc2)cc1F +Cc1cccc(CCC(=O)N2CCOCC2C2CC2)c1 +CN(C)c1cc(C(=O)N2CCCC(NS(C)(=O)=O)C2)ccn1 +COc1ccc(CC(=O)N2CCCC2c2c(C)noc2C)cc1 +Cc1occc1C(=O)NCc1csc(NC(=O)c2ccoc2C)n1 +COc1cc(C2NC(=O)c3cc(Cl)ccc3N2)ccc1O +Cc1ccc(-n2cnc(C(=O)N(C)CC(=O)N(C)C)n2)cc1 +CCOC(=O)CC1CCCCN1C(=O)c1cccc(OC)c1OC +CNC(=O)Cc1ccc(-c2ccc(S(C)(=O)=O)cc2)cc1 +O=C(CCC1NC(=O)c2ccccc2N=C1O)NCc1ccncc1 +COCc1nn(CCO)c(N)c1-c1nc2ccccc2c(=O)[nH]1 +N#Cc1ccc(C(=O)NCc2ccnc(-n3cccn3)c2)cc1 +CC(C(=O)NCc1ccccn1)n1cc(Br)cn1 +COc1ccc2cc(C(=O)NCCC(=O)Nc3nccs3)[nH]c2c1 +CCn1nc(CNc2ccc(Cl)cc2)[nH]c1=O +Cc1ccc(NCc2nc(-c3ccco3)no2)cc1-n1nnnc1C +N#Cc1ccc(NC(=O)CCC(C#N)c2cccs2)cc1 +CC(=O)Nc1ccc(C(=O)Nc2cccc(Cl)c2Cl)cc1 +CC1CCC(N(C)C(=O)Nc2cccc(N3CCNC3=O)c2)CC1 +O=C(NCc1nc(C(F)(F)F)cs1)c1ccc(Cl)cc1O +Cn1cc(-c2ccnc(N3CCCC(CN4CCCC4=O)C3)n2)cn1 +CCOc1cccc2n[nH]c(=NC(=O)Nc3ccccc3)n12 +COc1ccc(F)c(NC(=O)c2cc(C(C)C)[nH]n2)c1 +CCc1ccc(NCc2ccc(C(=O)N3CCCC3)cc2)cc1 +CC1CC(C)CN(C(=O)Nc2cccc(C#N)c2)C1 +CC(O)CNC(=O)C1CC(=O)N(CCc2ccccc2)C1 +CC(C)NC(=O)CN1CCN(C(=O)CCSc2ccccc2)CC1 +CCNC(=O)C1CCN(c2nc(-c3ccccn3)nc(C)c2C)CC1 +COCCNC1(C(=O)OC)CCCc2ccccc21 +Cc1ccc(C(C)NC(=O)Nc2ccnc(OCC(F)(F)F)c2)o1 +Cc1ccc(NC(=O)CN(C)C(=O)CCn2cc(C)cn2)cc1 +Cc1ccccc1NC(=O)N1CCCC1c1c(C)noc1C +Cc1ccc(C(C)NC(=O)Cn2cc(Br)cn2)cc1C +O=C1CNC(c2ccc(Br)cc2)c2ccccc2N1 +CCN(CC)S(=O)(=O)NC(C)(C)c1nc(C)c(C)s1 +CC(NC(=O)NCc1ccoc1)c1ccc2c(c1)CCC(=O)N2 +COC(=O)c1ccc(-c2noc(COCC3CCCO3)n2)cc1 +NC(=O)NCC(=O)Nc1ccc(Br)c(C(F)(F)F)c1 +COc1ccc(OC)c(NC(=O)c2ccc(F)cc2-n2cnnn2)c1 +COC(=O)Nc1ccc(OC(=O)c2sccc2C)cc1 +CCCCc1ccc(NC(=O)Cn2cnc(C)cc2=O)cc1 +Cc1n[nH]cc1NC(=O)c1cnc(C(C)(C)C)s1 +CN(C1CCOCC1)S(=O)(=O)c1ccc(Cl)c(N)c1 +Cc1nnc(SCC(=O)Nc2ccc(F)cc2C)s1 +Cc1ccc(CC(=O)NCc2nc3ccccc3s2)cc1 +Cc1cc(=O)oc2cc(OCC(=O)NCCO)ccc12 +O=S(=O)(c1cccnc1)N1CCCCC1c1nncn1CC1CC1 +CCNC(=O)c1ccc(NC(=O)NCCc2cccs2)c(C)c1 +COCCNC(=O)C1CCCN(c2nc3c(C)cc(C)cc3s2)C1 +O=C(Cc1cccc(Cl)c1)NCc1cc(=O)[nH]c2ccccc12 +CCOc1ccc(C(=O)NCC(=O)N2CC(C)CC(C)C2)cc1 +O=C(c1ccc(F)cc1)N1CCCCC1CCO +Cc1ccc(OCC(=O)Nc2cc(N)ccc2C)c(Br)c1 +Cc1nc(-c2ccccc2Br)n(C)c1C#N +O=C(COc1nncc2ccccc12)N1CCCc2ccccc21 +O=C(Nc1ccncc1)NC1CCc2nnc(Cc3ccccc3)n2C1 +COC(=O)c1sc(NC(=O)C2CC2c2ccco2)nc1C +CCN(C1CC1)S(=O)(=O)c1cc(C)c(OC)cc1C +O=C(NC(c1ccccc1)C1CC1)c1cn(Cc2ccccc2)nn1 +CCOc1ccc(CC2COc3cc(OC)ccc3C2)nn1 +CCC(OC)C(=O)Oc1ccc(Cl)cc1C(N)=O +CNC(=O)CN(C)C(c1cccnc1)c1ccc(Cl)cc1Cl +O=C1NCC2CN(Cc3ccc(OC(F)(F)F)cc3)CCN12 +CCCCNC(=O)C1CCCN1C(=O)c1ccc(OC)cc1OC +Cc1nnnn1C(Cc1ccc(F)cc1)C(=O)NCc1ncn(C)n1 +CC1Nc2ccccc2N(Cc2ccccc2)C1=O +O=C(NCCC(=O)N1CCCC1)c1ccncc1F +CCCNC(=O)CNC(=O)N1CCN(c2ncccc2C#N)CC1 +COCCN(Cc1ccccc1)C(=O)c1cnn(C)c1C +O=C(c1ccc(-n2cccn2)nc1)N1CCC(Nc2cccnn2)CC1 +c1ccc2c(c1)oc1c(NCCc3nnc4n3CCCC4)ncnc12 +Cc1ccc(C(C)NC(=O)Nc2ccc3c(c2)oc(=O)n3C)cc1 +COC(=O)C(NS(=O)(=O)c1c(C)noc1C)C(C)C +CCCc1n[nH]c(C2CN(C(=O)CC3CCCO3)CCO2)n1 +Cc1cc2cc(NC(=O)c3ccc(Cn4ccccc4=O)o3)ccc2[nH]1 +CC(C)(C)CC(=O)N1CCC(Nc2cnn(CC(F)F)c2)CC1 +Cc1nnc2sc(-c3ccc4c(c3)CCCN4)nn12 +CCOCc1cccc(NC(=O)c2ccc(C(=O)N(C)C)cc2)c1 +COc1cc(OC)cc(C(=O)N2CCC(CN3CCOCC3)CC2)c1 +NC(=O)C1(CNC(=O)c2cn(-c3ccccc3)nn2)CCOCC1 +Cc1ccc(C2(O)CCN(c3nnc(C4CCC4)o3)CC2)nc1 +C=CCCCN(C)C(=O)c1cn(C)nc1C(C)(C)C +CC1(CC(=O)NC2c3ccccc3CC2O)CCCCC1 +COc1ccccc1C#CCNC(=O)c1cccnc1 +COc1ccc(CNC(=O)c2ccc3c(c2)N(C)CCS3)cc1 +Cc1cccc(=O)n1CCC(=O)NCCN(C)S(C)(=O)=O +Nc1c(Cl)ccc2c1CS(=O)(=O)N(C1CCCC1)C2 +CCOc1nn(CC)cc1C(=O)Nc1ccc(OC(F)(F)F)cc1 +COc1cc(C)c(C(=O)c2ccc(N)cc2)cc1C +Cc1ccc(NC(=O)CCSc2ccccn2)cc1-n1cnnn1 +Cc1ccccc1C(=O)NCC1(c2cccs2)CCOCC1 +c1nc(CCNc2nc3nonc3nc2N2CCCCCC2)cs1 +CC(=O)N1CCN(CCOc2cccc(Br)c2)CC1 +Cc1ccc(-n2ccnc2S(C)(=O)=O)cc1Cl +N#Cc1ccc(S(=O)(=O)CCN2CCN(CC(F)F)CC2)cc1 +O=C(CNC(=O)c1ccc(-c2cscn2)cc1)NC1CC1 +CC1CN(C(=O)CC2Sc3ccccc3NC2=O)c2ccccc21 +CCCNC(=O)c1cc(S(=O)(=O)Nc2cccnc2)ccc1OC +O=C(NCCCn1cccc1)c1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)N2CCCN(C(=O)C3CCC3)CC2)cc1C +CN(CC(N)=O)C(=O)c1ccc(-c2ccccc2F)o1 +O=C(NCC(=O)N1CCCC1)c1ccccc1Nc1ccc(F)cc1 +Cc1ccc(C(=O)NCC(=O)Nc2ccc(C)cn2)cc1 +O=C(NC(C1CC1)C1CC1)C1COc2ccc(F)cc2C1 +Nc1ccc2nc(CC(=O)N3CCOCC3)oc2c1 +CC(C)N(C(=O)c1ccc(Cl)cc1)C1CCC1 +COCCS(=O)(=O)NCc1cccc(Br)c1 +CCCN(C(=O)C1C2CC3OC(=O)C1C3C2)c1c(C)cc(C)cc1C +CCC(=O)N1c2ccccc2CC1C(=O)NCCCN1CCCC1=O +COc1ccccc1SCc1ccc(C(N)=O)cc1 +O=C(c1ccc2cc[nH]c2c1)N1CCN(Cc2ccccc2)CC1 +Cc1cc(NC(=O)C2CCCN2C(=O)C2CC2)n(C)n1 +Cc1noc(NC(=O)CNC(=O)CC(C)(C)C)n1 +O=C(Cc1ccccn1)c1cc(Cl)cc(Cl)c1 +CNC(=O)c1cccc(NCC(=O)N2CCc3sccc3C2)c1C +CC(C)(C)NC(=O)c1ccc(NC(=O)NCc2cccnc2)cc1 +COC(=O)c1cccc(CCNC(=O)c2cc3occc3[nH]2)c1 +Cn1c(=O)[nH]c(=O)c2c1nc1[nH]c(-c3ccccc3)cn12 +CCN(Cc1ccc(F)c(F)c1)C(=O)c1cn[nH]c1 +Cc1cc(Br)ccc1N1CC(C(N)=O)CC1=O +O=C(c1cccc(OCC(F)(F)F)n1)N1CCN(CCO)CC1 +O=C(Oc1cccc2cccnc12)c1cc(=O)[nH]c2ccccc12 +Cc1ccc(NC(=O)CSc2nnc(C3CC3)n2C)c(F)c1 +COc1ccccc1CNc1ncnc2c1cnn2-c1ccccn1 +CCC(C(=O)N1CCN(C(C)c2cccnc2)CC1)c1ccccc1 +CCN(CC)C(=O)Cn1c(C2CC(=O)N(C)C2)nc2ccccc21 +Cc1ccc(S(=O)(=O)Nc2ccc(S(C)(=O)=O)cc2C)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccc2nnc(C)n2c1 +Cc1nc2ncccc2cc1-c1nc(C2CC2)n[nH]1 +FC(F)(F)c1nnc(NCc2cnc(-c3cccnc3)s2)s1 +CC(C)n1c(C2CCCN(C(=O)NC3CCCC3)C2)nn(C)c1=O +O=C(Nc1cccc(-c2cn[nH]c2)c1)C1CCCC1 +Cc1cc(NC(=O)COc2nc3ccccc3nc2C)no1 +O=C(Nc1ccccc1)c1nnc(CCC(=O)N2CCCC2)s1 +Cc1ccc(CNC(=O)c2csc(CC(C)C)n2)cc1 +Cc1c(C)c2cc3c(=O)ccoc3c(C)c2oc1=O +Cc1ccc(S(=O)(=O)Nc2ccn(C)n2)cc1 +CC(C)CC(C)OCCC(=O)N=c1[nH]nc2ccccn12 +Cc1ccc(-c2cnc(CCC(=O)NCC3CCCO3)o2)cc1C +CCC(CC)(CC)CNC(=O)N1CCNC(=O)CC1 +CC(C)c1nnsc1CNC(=O)c1cn2cccnc2n1 +c1ccc2c(c1)CC(NCc1ccnc(OC3CCOC3)c1)C2 +Cn1cccc1C(=O)N1CCCC2(CCN(c3cccnc3)CC2)C1 +C=CCNC(=O)Nc1ccc(NC(=O)c2csnn2)cc1 +Cc1c(C(=O)OCC2CC=CCC2)cnn1-c1ccccn1 +Fc1cc(CN2CCOC3(CCC3)C2)ccc1Cl +COc1ccc(C(NC(=O)Nc2ncc(C)s2)C(C)C)cc1 +OCc1nnn(-c2ccc3c(c2)OCO3)c1-c1cccs1 +Cc1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1C +OC(CNc1ccc(Br)cc1)c1ccccc1 +CCCCOc1cccc(C(=O)Nc2ccccc2C(N)=O)c1 +CCN(C)S(=O)(=O)c1c(C)nn(CC(=O)NC2CCCC2)c1C +CC(=O)c1ccc(OCC(=O)c2cn(CCC#N)c3ccccc23)cc1 +C#CCOC(=O)c1cc(-c2cccs2)nc2c1c(C)nn2C +Nc1nccnc1C(=O)N1CCN(S(=O)(=O)N2CCCC2)CC1 +Cc1cccc2nc(CNC(=O)CSc3nncs3)n(C)c12 +Cc1cccc(NC(=O)CCc2cccc(N)c2)c1C +COc1ccc(CNC(=O)NCCC(N)=O)cc1Br +CCNC(=O)CSc1nc2ccccc2c(=O)n1C1CCCC1 +C=CCNC(=O)c1ccccc1NCC(=O)N(C)C1CCC(C)CC1 +Cc1nsc(NC(=O)c2ccc(OC(C)C)cc2)n1 +Cc1cc(N2CCN(Cc3nnc(C(C)C)o3)CC2)nc(C)n1 +CCN(CC1CCOC1)C(=O)CN1C(=O)C(C)Oc2ccccc21 +CCCOC(=O)c1ccc(-n2nnc(CO)c2C2CC2)cc1 +Cn1ccnc1C(NC(=O)COc1ccccc1F)c1ccccc1 +CC(C)c1cc(C(=O)NC2(c3ccccc3)CCOCC2)n(C)n1 +Cc1ccc(N)cc1S(=O)(=O)Nc1cccc(C(F)(F)F)c1 +COc1cc(-c2nnc(-c3cccc(F)c3)o2)cc(OC)c1OC +CC1Nc2ncnn2C(c2ccc(Br)cc2)C1C(N)=O +CCOCc1ccc(CNC(=O)c2c(C)c(C)nn(C)c2=O)cc1 +COc1ccccc1OCC(=O)NCC1(O)CCc2ccccc21 +CCCc1nnc2sc(-c3cnn4cccnc34)nn12 +Cc1cccn2c(=O)cc(CSc3nccn3C)nc12 +Cc1noc(C)c1CSc1nnc(-c2ccccc2)n1N +COc1cc2c(cc1CNC(C)C(=O)N1CCCCC1)OC(C)C2 +Cc1c(F)cccc1NC(=O)COC(=O)c1ccccc1N +O=C(c1cc(C2CC2)n[nH]1)N1CCCN(c2ccc(F)cc2)CC1 +NC(=O)COc1ccc2nc3n(c(=O)c2c1)CCC3 +CC(C)c1cncnc1N1Cc2cnc(-c3ccccc3)nc2C1 +OCCN1CCN(c2cc(C(F)(F)F)nc3c(F)cccc23)CC1 +Nc1cccc(Cn2c(=O)c(Cc3ccccc3)nn3cnnc23)c1 +Cc1cc(C)cc(OCC(=O)NC2CCCNC2=O)c1 +CCCCN1C(=O)CCc2cc(NS(=O)(=O)CC(C)C)ccc21 +NC(=O)c1cc(NC(=O)CC2CCCC2)ccc1Cl +CC(C)C(NC(=O)Cc1ccc(F)cc1F)C(N)=O +CCc1cccc(CC(=O)NCc2csc(=O)[nH]2)c1 +Cc1nc(CC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cs1 +CC(C)(C)C(=O)N1CCC(C(=O)Nc2ccc3c(c2)CCC3)CC1 +CCCNC(=O)c1cccc(C(=O)NCc2cc(F)ccc2F)c1 +O=C(CNC(=O)c1cccs1)NCc1csc(C2CC2)n1 +c1cc(-c2noc(-c3coc(CN4CCOCC4)c3)n2)ccn1 +CN(Cc1cnn(C)c1)C(=O)Nc1cnn(-c2ccccc2Cl)c1 +Cc1cccc(CNC(=O)c2cn3c(n2)COCC3)c1 +COc1ccc(-c2nc(NC(=O)CC(C)(C)C)n[nH]2)cc1 +CN1CCN(C(=O)NCCC(=O)N(C)C)C(c2ccccc2)C1 +COc1ccc(C2CCCN2S(=O)(=O)N(C)C)cc1 +CN(Cc1ccccc1)C(=O)NCCNS(=O)(=O)c1ccccc1 +Cc1cccc(C2(C(=O)NCc3cnn(C)c3)CCCCC2)c1 +CCNC(=O)c1ccc(CNC(=O)c2occc2C)cc1 +O=C(c1cccnc1)N1CCc2ncnc(-c3ccsc3)c2CC1 +Cc1cc(C2CCCN2S(=O)(=O)c2cc(F)ccc2F)no1 +COc1cc2oc(=O)c(CC(=O)N3CCCCC3)c(C)c2cc1Cl +O=C(c1ccccc1)N1CCN(C(=O)N2CCCCC2)CC1 +CNC(=O)c1cc(Cl)ccc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C +CCCC1CN(C(=O)Nc2cc(F)c(OC)cc2F)CCO1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccc(C#N)cc1 +CC(C)(O)CN1CCN(C(=O)Cc2ccc3c(c2)CCC3)CC1 +CCCCCC(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1 +COCC(C)NC(=O)COc1cccc(Br)c1 +COc1cccc2c1N(CC(=O)N1CCNC(=O)C1)CCC2 +Cc1[nH]ncc1S(=O)(=O)N1CCN(S(N)(=O)=O)CC1 +CCc1noc(C)c1C(=O)NCCc1cc(F)cc2c1OCOC2 +COCC(=O)N(Cc1cc(-c2ccc(C)cc2C)on1)C(C)C +CCOc1cc(C)c(C(O)CCN2CCOCC2)cc1C +CSc1ccc(C=Cc2nc(-c3ccc(C#N)cn3)no2)cc1 +CCC(C(=O)N(C)c1ccc(S(C)(=O)=O)cc1)c1ccccc1 +Cc1cc(CNC(=O)COc2ccccc2C#N)ccc1F +COc1cccc2c1OCC(NC(=O)Cc1c(F)cccc1Cl)C2 +Cc1cc(-c2cc(O)nnc2C2CCN(C(=O)CC(C)C)CC2)on1 +Cn1cc(C(=O)NCc2cccc(S(N)(=O)=O)c2)c2ccccc21 +CCNC(=O)c1nn(-c2ccc(OC)cc2)c(OC)cc1=O +CCc1noc(CNc2cccc(Cl)c2-n2cccn2)n1 +CC(C)(NC(=O)CNC(=O)COc1ccccc1)c1cccc(F)c1 +CC(=O)Nc1ccc(Oc2ccc(CC#N)cc2)nc1 +CC(C)(C)n1ncc2c(=O)n(CC(=O)Nc3cccc(F)c3)cnc21 +CC(c1ccccc1)N1CCN(c2ccccc2N)CC1 +Nc1nc2c(c(=O)[nH]1)CCN(C(=O)c1ccc3ccccc3n1)C2 +CC(C)NC(=O)COC(=O)CCn1nnc2ccccc2c1=O +CN(Cc1cccc(C#N)c1)C(=O)c1cc2ccccc2[nH]1 +CC(C)C(NC(=O)c1cnn2ccn(C)c12)c1ccccn1 +O=C(NCC(=O)N1CCCCC1)c1cnn2c1OCCC2 +CSc1ncccc1C(=O)Nc1cc(C#N)ccc1C +Cc1onc(-c2ccccc2)c1CNC(=O)c1ccco1 +O=C1CCCN1c1ccc(S(=O)(=O)Oc2ccccc2)cc1 +CCc1nnc(NC(=O)NCc2ccc(OC)cc2OC)s1 +COC(=O)c1cc(Br)c(=O)n(CCN2CCOCC2)c1 +O=c1nc(Nc2nccc(-c3ccccc3)n2)[nH]c2ccsc12 +O=C(C1CCCc2[nH]ncc21)N1CCCC2(C1)OCCO2 +CC(C)Cn1ncc(C(=O)NC2CCCC3OCCC23)c1C1CC1 +Cc1nn(C)c(C)c1NC(=O)CNc1ccc(C(F)(F)F)cc1 +Cc1ccc2cccc(C(=O)N(C)CC3CC3)c2n1 +Cc1ccc(S(=O)(=O)NC(c2ccccc2)c2nccn2C)cc1 +CCOc1cc(C)ccc1NC(=O)c1cscn1 +COc1cc2c(cc1OC)-c1cc(-c3cc(C)n(C)c3C)cn1CC2 +CCN(C1CCCC1)S(=O)(=O)c1cccc(C(=O)OC)c1C +COCCCNC(=O)c1cc(S(=O)(=O)N2CCOCC2)cn1C +O=C(c1ccn(-c2ccc(F)cc2)n1)N1CCN(CCO)CC1 +COc1cccc(F)c1-c1nc2cnn(-c3ccccc3)c2[nH]1 +CC(NC(=O)c1cc(Cl)cn1C)C(=O)NC1CCCC1 +O=C(NC1CNCc2cc(Cl)ccc21)c1ccccc1 +CC(C)C(=O)NCCNC(=O)c1c[nH]c2cccc(F)c12 +Cc1c[nH]nc1-c1nsc2occ(Br)c12 +O=C1CCCN1CCCC(=O)N1CCCCC1c1ccc(F)cc1 +Cc1ccc(N2CCC(C(=O)Nc3cccnc3)C2=O)cc1 +COc1ccc(CNC(=O)c2cn3cc(C)ccc3n2)c(OC)c1 +Nc1nn(Cc2cccc(C(F)(F)F)c2)cc1Cl +COC(=O)CCCN1CCNc2cc(Cl)ccc21 +O=C(CCSc1ccccc1Cl)Nc1nncs1 +Cc1cccc(OC(F)F)c1NC(=O)NCCC(=O)N(C)C +CN1C(=O)CC(C(=O)Nc2ccc(CC#N)cc2)C1c1cccnc1 +N#Cc1ccc(F)c(CNC(=O)C2COc3ccc(F)cc3C2)c1 +CCOc1c(OC)ccc2c1C(c1ccc(N)cc1)NCC2 +CCc1ccc(OC2CNC(C(=O)OC)C2)c(OC)c1 +CNC(=O)COc1ccccc1CN(C)Cc1ccc(C)s1 +COC(=O)c1c(NC(=O)c2ccc(NC(C)=O)cc2)sc(C)c1C +CC1(C)C(=O)NCCN1C(=O)c1ccc(N2CCOC2=O)cc1 +COCCC(=O)NCC1CC12CCc1ccccc12 +CC(C)Sc1nnc(CCC(N)=O)n1Cc1ccco1 +Cc1ccc(-c2cc(CC(=O)NCc3cccnc3)no2)cc1 +CCCc1nnc(NC(=O)N2CCC(C(=O)NC)CC2)s1 +Cc1cc(CN(C)C(=O)c2sccc2C2CC2)no1 +Cc1ccc(C(=O)NCCNC(=O)COc2ccccc2F)cc1F +Cc1cccc(C(=O)N2CCC(C(O)c3ccccc3)CC2)c1 +Cc1ccc(NC(=O)N2CCCC(O)C2)cc1C(=O)NC(C)C +O=C(Cn1ccnc1)NCc1ccccc1Oc1ccccc1F +CCc1ncc2c(n1)CN(C(=O)c1ccn(C(C)(C)C)c1)C2 +COc1ccc(C(=O)NC(C#N)c2ccccc2)cc1OC +OCCSc1nnc(Cc2ccccc2)n1Cc1ccccc1 +Cn1ccc2c(-c3ccc(S(N)(=O)=O)cc3F)ccnc21 +CCC(=O)N1CC(c2nc(C)cc(Nc3cnccn3)n2)C1 +Cc1nc(CC(=O)N(C)c2nccs2)cs1 +O=C(CN1CCN(c2ccccc2F)CC1)Nc1ccc(F)cc1 +Cc1ccc(C(=O)Nc2nc3c(s2)C(=O)CC(C)C3)cc1 +CCc1cccc(C)c1NC(=O)c1ccc(N)cc1Cl +CC1(C)CNc2cc(C(=O)CNCC3CCCO3)ccc2O1 +COc1ccccc1C1CC2(C)NC(=O)C1C(=O)N2 +COc1ccc(Cc2nnc3sc(-c4ccco4)nn23)cc1 +CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc1cccnc1 +Cc1cccn(Cc2ccc(C(F)(F)F)cc2)c1=O +Cc1nn(C)c2nc(N3CCN(C4CCCC4)C(=O)C3)sc12 +COc1ccc2c(CNc3cccc(C(C)=O)c3)cc(=O)oc2c1 +CCC(=O)Oc1ccc(C(=O)Nc2cc(C)ccc2O)cc1 +COCCN(Cc1ccco1)C(=O)c1ccc(-c2nc(C)no2)cc1 +CCCOc1cccc(CNC(C)C(=O)N(C)C)c1 +O=C(NCCO)Nc1cccc(C(=O)NC2CC2)c1 +O=C(COc1ccc(-c2ccccc2)cc1)NCc1ccncc1 +Cc1ccc(NC(=O)c2cccc(OCC(F)F)n2)cn1 +CC(C(=O)NCCc1ccccc1)N(c1ccccc1)S(C)(=O)=O +O=C(C(c1ccccc1)c1ccccc1)N1Cc2cncnc2C1 +CNC(=O)C(CC(C)C)NC(=O)c1nn(-c2ccccc2)cc1OC +CSc1nc(C)c(CCC(=O)NCC(C)C#N)c(C)n1 +COc1ccc(CNC(=O)CSc2nc(C)cc(C)n2)cc1F +CCCCCNC(=O)C1CN(S(=O)(=O)C2CC2)C1 +COCc1nc(CNC(=O)C(C)(C)NC(=O)c2cccs2)no1 +COc1ccc(C(C)=O)cc1S(=O)(=O)NC1CC1 +Cc1cccc(N2CC(C)N(C(=O)c3cc(N)[nH]n3)CC2=O)c1 +Cc1ccc(NCC(=O)n2nc(C)cc2C)c(C)c1 +O=C1CCN(Cc2cc(Cl)c3c(c2)OCCCO3)CCN1 +CCOC(=O)N1CCC(NC(=O)NC(C)C(C)CC)CC1 +O=C(NCC1CC1)Nc1cccn(Cc2ccccc2)c1=O +Cc1cc(C)c(C(=O)N(C)Cc2nccn2Cc2ccccc2)c(C)c1 +Cc1ccc(OCCNC(=O)Nc2ccccn2)cc1 +CC(C)CC(NS(=O)(=O)c1cn[nH]c1)C(=O)N(C)C +CCN(CC(=O)NC(C)C)C(=O)c1ccccc1Cc1ccccc1 +COC(=O)Cc1nn(-c2ccc(Cl)cc2)c2c1nnc1ncnn12 +CN(Cc1cnc(C(C)(C)C)nc1)Cc1nc2ccc(F)cc2[nH]1 +COc1nc2ccccc2nc1CCC(=O)N1CCCCC1 +CN(CCC#N)S(=O)(=O)N1CCc2ccccc21 +O=C(CNC(=O)c1ccco1)OCC(=O)N1CCCCCC1 +Cc1ccccc1-n1ncc(C(=O)OCc2cccnc2)c1C1CC1 +CCc1ccc(C(=O)N2CCCN(C(=O)OCC(C)C)CC2)o1 +N#Cc1cccc(-c2ccc(C3OCCO3)cc2)c1 +Cc1ccccc1OCc1nc2cccc(N)c2o1 +COc1ccc(Oc2cc(CNC(=O)c3ccccc3)ccn2)cc1 +CCOc1ccc(CN(C)C(=O)c2ccc(-n3cnnn3)cc2)cc1 +CCCCS(=O)(=O)Nc1cccc(C(=O)OC)c1 +CC(C)(C)OC(=O)NC(C)(C)C(=O)NCc1ccoc1 +Cc1ccc(-c2cc(C(=O)NCC(C)O)on2)cc1 +CCNC(=O)c1ccc(Cl)cc1NCC(=O)N(C)C +CN(C)c1cccc(C(=O)NCC(=O)OCc2ccccc2)c1 +CCCCC(NC(N)=O)C(=O)N1CCC2(CC1)OCCO2 +c1cc(CN2CCCC3(CC2)OCCO3)nc(N2CCOCC2)n1 +COc1ccccc1NCC(=O)N1CC(=O)Nc2ccccc21 +CCCn1nccc1C(=O)Nc1cccc2cccnc12 +Cc1nc(CC(=O)Nc2ccccc2OC(F)F)cs1 +COc1ccc2c(C)nc(NS(=O)(=O)c3ccc(N)cc3)nc2c1 +COc1ccccc1CCNC(=O)c1nn2ccccc2c1Cl +NS(=O)(=O)CCNC(=O)c1cccc(C(F)(F)F)c1 +COC(=O)c1ccn(CSc2c(F)c(F)cc(F)c2F)n1 +COc1ccc(-c2nc(=O)c3ccccc3o2)cc1OC +Cc1ccc(C(=O)C2CCCN2C(=O)c2cccnc2)c(C)c1 +CCOCc1ccccc1CNC(=O)c1ccc(C(=O)N(C)C)cc1 +CCC1CCCN(C(=O)c2n[nH]c3ccc(C)cc23)C1 +O=C(Oc1cccc(Br)c1)C1CCC1 +O=C(CN1CCN(C(=O)c2ccco2)CC1)Nc1ccc(Cl)cn1 +O=C(NCC1CCN(c2ccccc2)C1)N1CCC(CO)CC1 +Cc1cnc(C(=O)NC(c2ccccc2)c2ccc(F)cc2)cn1 +CNc1nc(-c2ccco2)nnc1-c1ccc(Cl)cc1 +Cc1cc(C)c(C(=O)NCc2nc(C)sc2C)c(=O)[nH]1 +CCC(NC(=O)c1ccncc1F)c1ccc(Cl)cc1 +CCN1CCN(S(=O)(=O)c2cc(F)ccc2OC)CC1 +CN(C)C(=O)c1ccccc1NC(=O)CSc1ccncc1 +O=C(Cc1ccc[nH]1)NCC1(c2ccccc2)CCC1 +CCCN(c1ccc(F)cc1)S(=O)(=O)c1ccc2nncn2c1 +CN(CC1CC1)C(=O)c1ccc(OCC(N)=O)cc1 +COCc1cccc(CNC(=O)NC2CCCCC2)c1 +CCCc1nc(-n2cccc2)sc1C(=O)NCCN1CCOCC1 +CNC(=O)c1cccc(OC(=O)c2cccnc2N2CCCCC2)c1 +Cc1ccsc1CNC(=O)c1ccc2ncsc2c1 +COc1cccc(NS(=O)(=O)c2ccc(F)c(F)c2F)c1 +Cc1cc(NC(=O)c2cc(S(N)(=O)=O)c(C)o2)ccn1 +COC(=O)CC(C)NC(=O)C1CCN(c2ncccn2)CC1 +CC1CC(C)CN(C(=O)Cc2csc(-c3cccnc3)n2)C1 +N#Cc1ccc(OCCn2nc3ccccn3c2=O)c(Cl)c1 +O=c1[nH]c2ccc(S(=O)(=O)NCc3ccco3)cc2[nH]c1=O +Cc1ncc(C(=O)N2CCCCCC2c2c(C)n[nH]c2C)c(C)n1 +COC(=O)CCCc1ccc2c(c1)NC(=O)C(C)S2 +O=C(Cn1cnc2sccc2c1=O)c1ccc2c(c1)OCCCO2 +CC(=O)NCCNC(=O)Cc1c(C)nn(-c2ccccc2)c1C +O=C(NCc1cccc(Br)c1)c1cc2ccccn2n1 +N#CCSc1ccccc1C(=O)NCc1ccccn1 +O=C(Nc1cccnc1)NC1CCCN(c2ccccc2)C1=O +O=C1CN=C(Nc2ccc(F)cc2)N1Cc1ccccc1 +Cc1nonc1NC(=O)c1cc(S(=O)(=O)N(C)C)ccc1Cl +COc1cc(OC)cc(OCCC(=O)n2ccnc2)c1 +COC(=O)c1ccc(NC(C)=O)cc1OCc1ccccc1 +CC(=O)Nc1cccc(NC(=O)Cc2ccc(F)cc2F)c1 +COc1cc(NC(=O)CNc2cccc(F)c2)cc(OC)c1 +COCCc1noc(C2CCCN(Cc3coc(C(C)C)n3)C2)n1 +O=C(NCCn1ccccc1=O)c1cc(F)ccc1O +Cc1cc(OCC(=O)NCC(N)=O)ccc1C(C)C +N#Cc1cccc(NC(=O)CCc2cc(Cl)cs2)c1 +O=C(C1CCCCC1C(F)(F)F)N1CCN(C2CCCC2O)CC1 +C=C(C)CN(CC)C(=O)COc1ccccc1C(=O)NC +COc1cccc(C(N)=O)c1OCC(=O)NCC(F)(F)F +CCOC(=O)c1cn(-c2ccccc2)c(=O)c2ccccc12 +CC(CC(O)c1ccccc1)Nc1ccccc1S(C)(=O)=O +CC(C)n1nccc1NC(=O)CN1CCOC(c2nccs2)C1 +Cc1cc(C)n(-c2ccc(N3CCN(S(C)(=O)=O)CC3)nn2)n1 +COC(=O)CCNC(=O)C(N)c1cccc(F)c1 +CC1CCCN(C(=O)Cn2ncc3c([nH]c4ccccc43)c2=O)C1 +CCCN1CCN(C(=O)Cc2ccc(C)cc2)CC1 +COc1ccc2cc(NC(=O)c3snnc3C)cnc2c1 +CCN(CC)c1ccc(C(=O)Nc2cnn(CC(N)=O)c2)cc1 +CCCCOCCNC(=O)c1[nH]nc(C)c1Br +C=CCNC(=O)c1ccccc1NC(=O)c1cccc(OC(F)F)c1 +O=C(NC1CCOC2(CCCCC2)C1)c1cc(F)cc2[nH]cnc12 +Cc1cc(C)c(CNC(=O)NCC2CCCO2)c(=O)[nH]1 +O=C(Nc1ccccn1)c1cnn(Cc2ccccc2Cl)c1 +Nc1ccc2onc(CC(=O)Nc3c[nH]c(=O)[nH]c3=O)c2c1 +CC(C)OCc1ccc(CNC(=O)c2csnn2)cc1 +O=C1CCC(Nc2cnc3cc(Cl)c(Cl)cc3n2)CN1 +Cc1noc2ncn(CC(=O)NCc3ccccc3)c(=O)c12 +Cn1ccc(NC(=O)C2COc3ccccc3C2)n1 +CC(C)CC1COCCN1C(=O)Nc1cccc(NC(=O)C2CC2)c1 +CCC1(O)CCN(C(=O)CCn2cnc3ccccc32)CC1O +Cc1cc(NC(=O)c2cc(F)c(Cl)cc2Cl)ccn1 +Cc1cc(CN(C)C(=O)Nc2cccc(-c3nc(C)c(C)o3)c2)no1 +COCCCNC(=O)CSc1ccc(Br)cc1C +CC(C)(C)c1ccc(NC(=O)NCCN2CCOCC2)cc1 +CCN(CC)C(=O)CN1CCN(c2ncccc2C(N)=O)CC1 +Cc1noc(COC(=O)Cn2ccc3ccc(Cl)cc32)n1 +CCn1nc(C(=O)Nc2ccc(OC)c3ccccc23)cc1C +Cc1ccc(NCc2nc(C(C)(C)C)nn2C)cc1 +COCCN1CCN(C(=O)CCc2c(C)n[nH]c2C)CC1=O +CN(Cc1ccc(O)cc1)C(=O)C1CC2C=CC1C2 +C=C(C)COC(=O)c1ccc(S(=O)C(C)C)cc1 +CS(=O)(=O)c1ccc(OCc2ccc(C#N)cc2)cc1 +O=C(CSc1cccc(C(F)(F)F)c1)NCc1csc(=O)[nH]1 +O=C(c1ccco1)N1CCC2(CCCN2C(=O)c2ccco2)CC1 +Cc1ccc(F)cc1NC(=O)COc1ccc(F)cc1 +COc1cc(CNC(=O)N2CCCC2C(C)C)cc(OC)c1OC +O=C(Cc1ccc[nH]1)Nc1cnn(CC2CCCO2)c1 +COc1ccc(CN2CCc3nc(N4CCOCC4)ncc3C2)cc1 +C=CCSc1nnc(-c2cccnc2)n1CC=C +CCOC(=O)C(NC)c1c(F)ccc(C)c1Cl +CCC(=O)Nc1cccc(NC(=O)c2c(C)cc(C)[nH]c2=O)c1 +O=C(c1cccs1)C1CCCN(C(=O)c2cc(C3CC3)n[nH]2)C1 +Cc1ccc(NS(=O)(=O)c2cc(N)cc(F)c2)cc1 +CC(=O)c1ccc(S(=O)(=O)C2CCCC2)cc1 +CC(=O)Nc1ccc(C(=O)OCc2nc3ccccc3nc2C)cc1 +Cc1cc(C)c2[nH]c(CN(C)CCc3cnn(C)c3)cc(=O)c2c1 +CCN(CC)C(=O)c1cc2cn(C3CC3)cc2s1 +Cc1cccc2ncc(C(=O)N3CCNC(c4ccccc4)C3)c(=O)n12 +CCc1ncc(C(=O)Nc2c(C)c(CC)nn2-c2ccccc2)cn1 +COc1cc(OC)cc(C(=O)N(Cc2ccc(F)cc2F)C2CC2)c1 +Cc1ccccc1-c1nnc(SCC(=O)Nc2ccon2)n1C +CCN(C(=O)C1CC1c1cccnc1)C1CCN(c2ccccc2)C1=O +Cc1ccc(S(=O)(=O)N(Cc2cccnc2)C2CC2)cc1F +COc1ccccc1CCC(=O)Nc1ccccc1 +Nc1ccc(C(=O)Nc2ccc(F)c(F)c2F)cc1 +COCC(O)(c1ccccc1)C(c1ccccc1)c1ccccn1 +CN(C)c1cc(C#N)nc2ccc(N3CCCCC3)cc12 +O=C(Nc1ccccc1)C1CC2CN(c3ncccn3)CC1O2 +Cc1nn(C)c(C)c1CNc1cccc2[nH]ncc12 +CC(=O)N1CCc2cc(-c3cc(C#N)nn3-c3ccccc3)ccc21 +NC(=O)c1ccc(C2CN(C3CCCCCC3)CCO2)nc1 +Cc1ccccc1NC(=O)CN1CCN(C(=O)c2ccccc2)CC1 +Cn1cccc1C(=O)NCC1(NC(=O)c2cccn2C)CCOCC1 +O=C(NCCc1ccc2c(c1)OCO2)c1cc(Br)c[nH]1 +Cc1c(Cl)cccc1-n1nnc(C(N)=O)c1C +CC(=O)Nc1ccc(OC(C)=O)c(-c2nc3ccccc3o2)c1 +Cc1cccc(NC(=O)c2cc(C(F)(F)F)n[nH]2)c1 +CC(O)Cn1c(CCCO)nc2cc(Cl)ccc21 +CS(=O)(=O)N1CCc2cc(C(=O)NCCc3ccccn3)ccc21 +Cc1noc(NC(=O)C(C)OCC2CCCO2)n1 +Cc1ccc(C)c(C(=O)NCCCn2c(C)nc3ccccc32)c1 +CCc1nnc2n1CC(NC(=O)CCc1ccsc1)CC2 +CCCNC(=O)N1CCN(S(=O)(=O)c2cccc(C)c2)CC1 +CCOC(=O)C(O)Cc1[nH]ncc1-c1ccccc1 +Cc1ccc(OC2CCN(C(=O)Nc3ccc(Cl)cc3)CC2)nn1 +CN(Cc1cnn(C)c1)C(=O)c1cc2c(s1)CCCC2 +O=C(NCc1cccc(Cl)c1)C1CCN(c2cn[nH]c(=O)c2)CC1 +NC(=O)c1c(NC(=O)CCOc2ccccc2)sc2c1CCCC2 +CN(CCC#N)C(=O)c1ccc(OCC(F)F)nc1 +Cc1cc(C)n(-c2ccc(NC3CCCC4OCCC34)nn2)n1 +Cc1ccccc1OCC(=O)NCC1CCN(c2ncccn2)CC1 +Cc1noc(C)c1COc1ccc(CN2CCOC(C)(C)C2)cc1 +Cc1cccc(C(=O)N2CCSc3ccc(N)cc32)c1 +CCNC(=O)c1ccc(NCc2cc(=O)n3ccccc3n2)c(C)c1 +CCNC(=O)CNC(=O)c1cc(N2CCCC2=O)ccc1Cl +COCCN1CC(C(=O)Oc2ccccc2F)CC1=O +COc1c(C(=O)NC2CC2)sc2cccc(F)c12 +Cc1nn(Cc2cccc(C(=O)NCC3CCCO3)c2)c(C)c1Cl +O=C(Nc1ccnc2ccnn12)c1cc2ccccc2c(=O)[nH]1 +Nc1ccc2oc(CC(=O)N3CCCCC3CCO)nc2c1 +CCNS(=O)(=O)c1cc(N)c2c(c1)CCCC2 +Cc1cc(S(=O)(=O)NC(C)(C)CO)ccc1F +O=C(Nc1cnc(C2CC2)nc1)N1CCc2c(F)cc(F)cc2C1 +Cn1c(C(=O)NCc2cccs2)cc2c(=O)oc3ccccc3c21 +COc1ccc(Cl)cc1NC(=O)c1cccnc1SC +CNC(=O)c1cc(C(=O)c2ccc(Cl)cc2)c[nH]1 +O=S(=O)(c1c(F)cccc1Cl)N1CCC(n2ccnn2)CC1 +O=C(CCC(=O)c1cccs1)Nc1ccc2c(c1)CCC2 +C=CCNC(=O)c1ccc(N(CC=C)S(C)(=O)=O)cc1 +N#Cc1cc(NS(=O)(=O)c2ccc(F)cc2F)ccc1Cl +COc1cccc2cc(CNc3cccnc3)oc12 +O=C(Cn1nnc2ccccc2c1=O)Nc1ccc(-c2cc[nH]n2)cc1 +O=C(C1CC1)N1CC(c2nc(-c3ccco3)no2)C1 +O=C(C1Cc2ccccc2O1)N1CCCN(Cc2cccs2)CC1 +CN(Cc1ccncn1)C(=O)c1cccc(CCC(C)(C)O)c1 +Nc1ccccc1NC(=O)c1ccccc1Br +O=C(NCc1cccnc1)c1ncoc1-c1ccccc1F +CCOC(=O)c1cnc(SC)nc1N1Cc2cnn(CCO)c2C1 +COCC(=O)N1CCC(c2nccnc2Oc2cccnc2C)CC1 +CN(Cc1cccc(C#N)c1)C(=O)c1ccc(N2CCNC2=O)cc1 +CC(=O)N1CCCc2ccc(NC(=O)c3ccc(F)cc3)cc21 +CC1CN(CCC(=O)Nc2sc3c(c2C#N)CCC3)CCO1 +CN(C(=O)c1cc(Cl)ccc1N)C1CCCCC1 +CCOc1c(OC)ccc2c1CCNC2c1cnoc1C +Cc1nn(-c2ccccc2)c2c1-c1nc(C#N)c(C#N)nc1C(C)(C)C2 +CN(C)C(=O)CSc1nnc(-c2ccccc2Cl)o1 +CCC(C)C(C)NS(=O)(=O)c1ccc2c(c1)CCCN2C(C)=O +O=C(CNC(=O)Nc1cccc(Cl)c1Cl)NCc1ccco1 +Cn1cccc(NC(=O)c2cnn(Cc3ccccc3Cl)c2)c1=O +C#CCNC(=O)c1c[nH]c2cc(OC)ccc2c1=O +Cc1c(F)cc(C(N)=O)cc1NCCOc1ccc(C#N)cc1 +CCC(NC(=O)NCC(O)c1cnn(C)c1)c1ccc(C)cc1 +CCOC(=O)c1c(SC)c2c(C)nn(-c3ccccc3)c2oc1=O +CCOC(C)c1nc(COc2cccc(F)c2F)cs1 +COc1nc(N(C)C)sc1CNCc1nc(C)no1 +Cc1nc(SCC(C#N)CCC#N)n(C2CCCCC2)c1C +COc1cccc(NC(=O)Cn2c(C3CC3)nc3ccccc32)c1 +Cc1cnc2c(c1)nc(Cc1ccc(Cl)cc1)n2CCCO +COCC(c1cccc(C(F)(F)F)c1)N(C)C(=O)c1ccncc1 +CCCC(=O)N1CCCC(C(=O)Nc2ccc(-n3cncn3)cc2)C1 +Fc1cccc(NCc2ccccc2-n2cccn2)n1 +CC(C)NC(=O)CSc1n[nH]c(=O)n1CCc1ccccc1 +Cc1ccccc1CC(=O)OCC(=O)Nc1ccc2c(c1)OCO2 +Nc1c(-c2cccc(F)c2)noc1C(=O)NC1CCCC1 +COCc1nc(C(=O)N2CCCC2c2c(C)nn(C)c2C)cs1 +CCN1C(=O)c2ccccc2NC1c1ccccn1 +Cc1nnnn1CCC(=O)N(CC#Cc1ccccc1)C1CCCC1 +CC(C)(CNC(=O)C1CC=CCC1)NC(=O)OC(C)(C)C +CCC(CO)NC(=O)NCc1ccc(N2CCCCC2=O)cc1 +COc1ccc(C(=O)Nc2c(N)nc[nH]c2=O)cc1 +Cc1cc(C(=O)NC(C)(C)c2cccc(F)c2)on1 +CCN(C(=O)OC(C)(C)C)C1CCN(C(=O)OC(C)(C)C)CC1 +CCN(CC)S(=O)(=O)c1ccc(C(=O)NCc2ccccn2)cc1 +CC(NC(=O)C1CCN(c2ccc(C#N)cn2)CC1)c1cccs1 +COc1ccccc1OCc1nnc2c(N)c(C)ccn12 +COc1cc(S(=O)(=O)Nc2c[nH]nc2C)ccc1Br +CCc1c(C(=O)N2CC(C)(C)C(C)(O)C2)csc1C +C=CCCCN(C)C(=O)C1Cc2ccccc2CN1C(=O)C(C)CC +CC(CO)NC(=O)c1nn(C(C)C)c(=O)c2ccccc12 +COc1ccc(C(=O)NCc2ccccc2C)c(OC)c1OC +CC(Oc1ccc(Cl)cc1)C(=O)N1CCCC1 +CC(NC(=O)C(C)S(=O)(=O)c1ccccc1)c1ccccc1 +CC(=O)NC(CC(=O)NCC(C)c1cccs1)c1ccc(C)cc1 +CC1CC(C)CN(C(=O)c2cc(-c3ccncc3)c3cnccc3n2)C1 +CC1(C)CN(c2ccc3nnc(C(F)(F)F)n3n2)C1(C)C +Cc1nc2cc3c(cc2n(CCCC#N)c1=O)CCCC3 +COc1ccc(CNc2cccc(C#N)c2)c(OC)c1OC +C=CCCCN(C)C(=O)c1c[nH]nc1-c1ccccc1F +CC(=O)c1ccc(OCC(=O)c2ccc(F)cc2F)cc1 +O=C1CCC(COC(=O)CSc2ccc3ccccc3c2)N1 +CCCNC(=O)CSc1nnc2[nH]c(=O)cc(-c3ccccc3)n12 +Cc1nccn1-c1cncc(C2CCCN2CC(=O)N(C)C)n1 +CN1CC2(CCN(c3nnc(C4CCC4)o3)C2)OC1=O +O=C1c2ccccc2NC(c2ccco2)N1C1CC1 +O=C(NCCSc1ccccn1)c1ccc(-n2cnnc2)nc1 +Cc1n[nH]cc1NC(=O)Cc1ccc(Cl)cc1Cl +CCc1ccc(OCC(=O)NC2CCN(C(=O)OC)CC2)cc1 +Cc1ccc(C)c(S(=O)(=O)NCc2ccoc2)c1 +O=C(Nc1cccc(-c2nnc3n2CCC3)c1)c1ccccc1Cl +CC(C)NC(=O)CNS(=O)(=O)c1cnc(N)nc1 +COC(C)(C)CNC(=O)NCC(O)c1ccc(Cl)c(F)c1 +O=C(c1ccc(COc2ccc(F)cc2)o1)N1CCCC1 +Cc1cn2c(CCC(=O)N3CC(C)Oc4ncccc43)csc2n1 +CC(NC(N)=O)C(=O)NCCN1CCN(c2ccc(F)cc2)CC1 +CC1CC1C(=O)NC1(c2ccc3c(c2)OCCO3)CCCC1 +CC(C)n1c(=O)n(CC(O)COC(C)(C)C)c2ccccc21 +Cc1ccc(C(=O)NCCCOC2CCCCC2)c(=O)n1C +CC1CC(C)CN(C(=O)Cn2cnc3ccc(Cl)cc3c2=O)C1 +CC12CC3CC(C)(C1)CC(C(=O)NCCN1CCOCC1)(C3)C2 +CCNC(=O)N1CCN(CCN(C)c2ccccc2)CC1 +Cc1nn(C)c(C)c1CN(C)C(=O)C(C)n1ncc(Cl)c1C +COCCCn1ccc(NC(=O)N2CC(C)OC(C)C2)n1 +CCOc1ccccc1-c1nnc(SCC(C)C(C)=O)o1 +N#CCCn1c(C(N)c2ccccc2)nc2ccc(F)cc21 +Cc1ccc(C)c2[nH]c(=O)c(CCNS(C)(=O)=O)cc12 +CCN(CC)C(=O)N1CCC(C(=O)Nc2ccc(Cl)cn2)CC1 +Cc1noc(C)c1CCCNC(=O)Nc1ccc(OC(F)F)cc1 +Cc1ccccc1-n1cc(C(=O)N(CC(N)=O)CC(C)C)cn1 +CC(=O)c1cccc(NC(=O)CNC(=O)c2ccc(F)cc2F)c1 +Cc1cccc(C)c1NC(=O)c1nccc2c(N)c(C)ccc12 +CC(=O)Nc1nc(C)c(S(=O)(=O)N2CCOCC2)s1 +CC(C)S(=O)(=O)c1c(SCC#N)sc(C#N)c1N +Cc1ccn2c(=O)cc(Cn3cnc4sccc4c3=O)nc2c1 +CSc1ncccc1C(=O)N1CCC2(CC1)OCCCO2 +Cc1cc(C(=O)N(C)Cc2ccc3nonc3c2)nc(C)n1 +O=C(CCSc1ccc2c(c1)OCCO2)NCc1ccco1 +COc1ccc(NC(=O)C2CCCN2C(=O)c2cccs2)cn1 +O=C(NC(c1ccccc1)C(F)(F)F)c1cc(-c2cccnc2)on1 +CC(=O)Nc1ccc(NCc2ccc(C)cc2C)cc1 +COC(=O)CN(C(=O)Cc1cc(C)ccc1C)C(C)C +CCn1c(=O)c2ccccc2n(CCC(C)C)c1=O +CCOc1ccc(C(=O)NCC(=O)N2CCC(C)CC2C)cc1 +CC(C)OCCOc1ccc(S(N)(=O)=O)c(F)c1F +COc1cccc(NC(=O)CSc2nc(C)nc(C)c2C(C)=O)c1 +CCOC(=O)CN(CC)C(=O)C(C)(C)c1ccccc1 +O=C(NCC1CCN(C(=O)c2cccnc2)CC1)c1ccccc1F +COc1ccc(C(=O)CNC(=O)C(C)(C)c2cccs2)cc1 +CCn1cnnc1CNC(=O)N1CCN(c2cccc(OC)c2)CC1 +CCCn1nnnc1Cn1nnc(-c2ccc(F)cc2)n1 +C#CCN(Cc1ccco1)C(=O)c1cc(Br)ccc1F +Cc1cc(C)n2nc(CC(=O)Oc3cccc(C)c3C)nc2n1 +Cc1cc(CNC(=O)Nc2cnccc2C)ccc1F +O=C(Nc1cccc(-c2ccn[nH]2)c1)c1ccc2ccccc2n1 +COc1cc(CNCC(O)c2ccco2)cc2c1OCCO2 +Cc1nn(-c2ccccc2)c(C)c1C(=O)OC(C)C#N +CC(C)CC1(CNC(=O)c2cccc(S(C)(=O)=O)c2)CCCC1 +CC(Sc1nccn1-c1ccc(C(C)C)cc1)C(=O)N(C)C +O=C(NCCNc1nc2ccccc2c(=O)[nH]1)c1ccccc1Cl +Cc1cc(C(=O)Nc2ccc(Cl)cc2C(N)=O)c(C)s1 +COc1cc(C)c(Br)cc1S(=O)(=O)N(C)C +CC(NC(=O)c1cc(F)c(Cl)cc1Cl)C(=O)NC(C)(C)C +CCCNC(=O)Nc1ncc(-c2cccnc2)s1 +CCCOc1ncccc1CNC(=O)c1n[nH]c2ccccc12 +Cc1cc2c(cc1-c1c(C#N)c(N)nc3c1C1CCC(C3)N1C)OCO2 +CN(C)c1ccc(C(=O)Nc2ccccc2C(=O)NC(C)(C)C)cn1 +Cc1nn(-c2ccc(C(=O)NCc3ccccn3)cc2)c(C)c1Cl +COc1ccccc1OCC(=O)NCc1ccccc1-n1cccn1 +O=C1CCCN1CC(=O)N1CCOC(Cc2ccc(F)cc2)C1 +CCOc1ccccc1NC(=O)NCc1ccsc1 +CC(C)N(Cc1cccs1)C(=O)c1cscn1 +CCn1c(C)c(N)c(=O)n1-c1ccc(F)cc1F +Cc1ccc(NC(=O)Cc2csc(-c3cccnc3)n2)c(F)c1 +Nc1ccc(C(=O)N2CCCC(=O)c3ccccc32)cc1 +Cc1noc(C2CCCN2S(=O)(=O)c2ccc(C(C)(C)C)cc2)n1 +CC(C(=O)N1CCCCC1)S(=O)(=O)c1ccccc1F +CCN(C)c1cccc(NC(=O)COc2cccc(F)c2)c1 +CCCC(C)CNc1cc(S(N)(=O)=O)cc(C)c1C +CC(C)C(=O)NCC1CCCN(C(=O)c2cc3ccccc3[nH]2)C1 +CCCNC(=O)c1cn(-c2ccc(C)c(C)c2)nn1 +CC(C)C(NC(N)=O)C(=O)N1CCC(C(=O)c2ccccc2)CC1 +Cc1ccc2cc3cc(C(=O)NCC4CCCO4)oc3nc2c1 +CCS(=O)(=O)N1CCCC(C(=O)Nc2ccccc2O)C1 +COCCOc1ccc(NC(=O)C(C)OC)c(C)c1 +CCC(C)n1ncc(C(=O)NCCc2cccc(O)c2)c1C1CC1 +CCC(CCO)NC(=O)NCC1CN2CCCCC2CO1 +COc1ccc(CC(=O)OCc2nnc(-c3cccc(C)c3)o2)cc1 +COCCCNC(=O)c1c[nH]cc1-c1ccccc1 +COc1ccc2c(C)c(CCC(=O)Nn3cnnc3)c(=O)oc2c1 +Cc1ccnc(NC(=O)CNC(=O)Cc2ccccc2)c1 +CCOc1ncnc(Nc2cccc(Br)c2)c1N +CCOc1c(OC)cc(Br)c2cc(C(=O)OC)[nH]c12 +CC=CCOC(=O)Cc1csc(NC(=O)c2ccco2)n1 +O=C1CCc2cc(C(=O)NCCc3cn4ccccc4n3)ccc2N1 +FC(F)CN1CCN(Cc2ccc(Oc3cnccn3)cc2)CC1 +CCN(CC)C(=O)CCC(=O)NC1CCCCC1OC +COC(=O)c1ccc(OC(C)c2ccc(C(=O)OC)o2)cc1 +Cc1cc(C)n(-c2nc(CCNC(=O)Nc3ccccc3)cs2)n1 +CC1CCCCN1S(=O)(=O)c1ccc(Br)cc1 +Cn1ccnc1SCCC(=O)Nc1ccc(F)cc1N +CCCCS(=O)(=O)N(C)c1ccc(N)cc1F +COC(=O)C(C)NC(=O)C(C)Oc1cccc(Cl)c1 +O=C1COc2ccc(-c3cscn3)cc2N1Cc1ccccc1 +CN(C(=O)C1CCCN1C(=O)C12CC3CC(CC(C3)C1)C2)C1CC1 +Brc1cncc(OCc2ccccc2)c1 +Cn1cc(NC(=O)CCc2ncc(-c3c(F)cccc3F)o2)cn1 +Cc1cc(Cl)c(C(=O)N2CCCCC2C(C)C)cn1 +CN(Cc1cnc(C2CC2)s1)C1CCN(c2ccccc2)C1=O +Cc1ccc(OCC(=O)NC2CC3C(=O)N(C)CC(=O)N3C2)cc1C +CC(C)c1csc(NC(=O)c2cccc(F)c2N)n1 +CCCC1CN(C(=O)c2sc(-c3ccccn3)nc2C)CCO1 +CCc1nnc(NC(=O)NCCc2ccc(F)cc2C)s1 +O=C(NC1CCCCC1)c1ccc2ncnc(N3CCCC3)c2c1 +C#CCCN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 +CC1(NC(=O)NCCCCN2CCOCC2)Cc2ccccc2C1 +CCn1nc(C(=O)NCCOc2cccnc2)ccc1=O +CN1CCc2c(c(-c3ccccc3C(F)(F)F)nn2CC#N)C1 +CSc1nc(N)n(-c2cnc3ccccc3n2)n1 +CCCn1ccc2cc(NC(=O)c3ccc(C)nc3)ccc21 +CCN(Cc1cnc2ccc(C#N)cn12)CC(O)c1ccc(C)cc1 +CC1CC=CCC1COC(=O)c1cccc(C(=O)N(C)C)c1 +CCc1nnc(NC(=O)Cc2csc(-c3ccccn3)n2)s1 +CCc1ccc(OCC(=O)Nc2ccccc2N2CCCC2=O)cc1 +Cc1ccc(-c2ccc(C(=O)N3CCOCC(CO)C3)cc2)o1 +O=C(Cn1c(-c2ccccn2)noc1=O)NCc1ccco1 +CC1CCCN(C(=O)c2ccc(COc3ccc(C#N)cc3)o2)C1 +CC(=O)Nc1cc2c(cc1Br)-c1ccccc1C2=O +COc1ccc(F)cc1NC(=O)Cn1cnnn1 +O=C(Cc1c[nH]c2ccccc12)Nc1ccc2c(c1)CCC2 +CCn1nnc2cc(C(=O)NC3(C)Cc4ccccc4C3)ccc21 +CS(=O)(=O)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +CC(C)(C)n1cc(C#N)cc1NC(=O)c1cc(=O)[nH]c2ccccc12 +CC(NC(=O)c1ccc(-n2cccn2)cc1)c1ccncc1 +CNS(=O)(=O)c1ccc(Cl)c(C(=O)N2CCOC(C)C2)c1 +CC(CC#N)N(C)C(=O)c1cc(S(C)(=O)=O)c(Cl)cc1Cl +COc1ccc(C#CCNC(=O)Cc2noc3ccccc23)cc1 +Cc1[nH]nc(-c2ccc3[nH]c(=O)[nH]c3c2)c1Br +CC(=O)C(C)n1c(=O)c2c(nc3oc(C(C)(C)C)cn32)n(C)c1=O +CCC(C)NC(=O)c1cc(-c2ccncc2)c2cnccc2n1 +CCNC(=O)c1cccc(CNC(=O)NCC(F)(F)F)c1 +N#Cc1c(-c2ccccc2)nn(-c2ccccc2)c1N +COc1ccc(Cl)cc1-c1ccc(C#N)c(=O)n1C1CC1 +COc1ccccc1S(=O)(=O)N1CCN(CC(O)C2CC2)CC1 +COc1c(CN(Cc2cccc(F)c2)CC2CCCO2)c(C)nn1C +CCc1onc(C)c1NC(=O)NCC1(C)COC1 +Cc1nn(C)cc1-c1ccnc(N2CCN(c3cnccn3)CC2)n1 +COC(C)C(=O)N1CCCCCC1c1ccco1 +CCn1c2ccc(C(N)=O)cc2c2cc(C(N)=O)ccc21 +O=C(NCc1ccc(CO)c(F)c1)Nc1ccc(F)cc1F +CCOC(=O)CN(C)C(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +O=S(=O)(NCc1nnc2ccccn12)N1CCCCCC1 +O=C(c1ccccc1)c1ccccc1C(=O)N1CCCC(O)C1 +CCOc1ccc(-c2nc(NC(=O)c3ccnn3C)sc2C)cc1 +CN(C)C(=O)CCC(O)c1ccc2c(c1)OCO2 +O=C(NCc1ccc(CO)c(F)c1)Nc1ccccc1Cl +O=C(NCc1cc(F)cc(Br)c1)c1ccccc1 +CCCc1ccc(C(=O)CSc2nnc(C3=NC=CC3)o2)cc1 +CCn1nnnc1-c1cccc(NC(=O)NCc2ncn(C)n2)c1 +OCC1CCCN(c2nn3cc(-c4ccc(F)cc4)nc3s2)C1 +COCCCNC(=O)N1CCCCCC1c1ccco1 +C#CCNC(=O)NCC(C)(C)c1ccc(OC)cc1 +CC(=O)NC(C(=O)NC(C)c1cc2ccccc2o1)C(C)C +COc1cccc2cc(C(=O)OCc3cccc(C(N)=O)c3)oc12 +Cc1nc(SCc2noc(-c3ccccc3O)n2)oc1C +CCc1onc(C)c1NC(=O)Nc1cc(C)cc(C)c1 +CCNC(=O)C(C)NC(=O)C(C)Oc1ccc(Br)cc1 +CC(C)c1cc(C(=O)N2CCC(C)(O)C(O)C2)nc2ncnn12 +Cc1cccc(C(=O)NCC(=O)N(C)C(C)c2ccccc2Cl)c1 +CCCCC(=O)Nc1nc2c(s1)CN(CC)CC2 +O=C(NCc1cccnc1)Nc1cnn(-c2ccccc2)c1 +CC(C)c1cc(CNC(=O)COc2ccc(Cl)cc2)on1 +Cc1nc(-c2cccc(F)c2)nc2c1CN(C1CCOC1)CC2 +Cc1nn(Cc2ccc(S(=O)(=O)N(C)C)o2)c(=O)c(C#N)c1C +Cc1cc(Br)cn2c(N)c(C(N)=O)nc12 +COc1cc(CNC(=O)NC(C)C(=O)N2CCCCC2)ccn1 +Cc1oc(C)c(C(=O)NCc2ccc(CS(N)(=O)=O)cc2)c1C +Nc1ccc(NCc2ccncc2)cc1C(F)(F)F +COc1ccnc(COC(=O)C2COc3ccc(F)cc3C2)c1 +CCn1c(=O)[nH]c2cc(C(=O)NC(C)C)ccc2c1=O +Cc1ccc(NC(=O)N2CCN(CCO)CC2)cc1 +Cc1ccc2[nH]cc(C(=O)NCC(O)C3CCCCC3)c2c1 +N#Cc1cc(N)cnc1N1CCCc2ccccc21 +Cc1nnc(C(=O)NCC(C)C)n1-c1ccccc1 +CN(Cc1nccn1C)S(=O)(=O)Cc1cccc(F)c1 +CCOc1ccccc1CNC(=O)NC(C)c1nncn1C +c1coc(-c2nc(CSc3nnc(C4CCCCC4)o3)no2)c1 +Cc1nn(C)cc1C(=O)NC(C)c1nc2ccccc2o1 +CN(CCN1CCOCC1)CC(=O)Nc1ccc(C#N)c(Cl)c1 +CCOC(=O)C1CCCN(C(=O)C2CN(S(=O)(=O)C3CC3)C2)C1 +O=C(Cn1nnc2ccccc2c1=O)Oc1cccc(-n2cccn2)c1 +Cc1ccc(CCNC(=O)Nc2cn(C)c(=O)cc2C)cc1 +CC(CC(Nc1ccc(Cl)cn1)n1cncn1)n1cncn1 +O=C(Cn1cnnn1)N1CCC(C(=O)N2CCCCCC2)CC1 +O=C1CCC(C(=O)NCCn2cnc(-c3ccccc3)cc2=O)N1 +CC(CC1CCCC1)C(=O)NCc1ccnc(-n2cccn2)c1 +COc1ccc(Cl)cc1NC(=O)NCc1ccncc1 +CCn1ncc(-c2ccccc2Cl)c(C(C)=O)c1=O +CCCCOc1ccc(-c2nc(C(C)N)cc(=O)[nH]2)cc1 +CCCN(CCO)S(=O)(=O)c1ccc(=O)[nH]c1 +CCc1cccc(C)c1NC(=O)c1cnn(C)c1N +CC1C(=O)Nc2ccc(C(=O)CSc3nnnn3C3CC3)cc21 +CC1(C)C(=O)NCCN1C(=O)c1ncn(-c2ccccc2)n1 +Cc1ccc(S(=O)(=O)C(C)C(=O)Nc2ccc(F)c(F)c2)cc1 +Cc1cc(F)ccc1CCNS(=O)(=O)N(C)CCC#N +COCCCNC(=O)c1sccc1Br +CCCc1oc(-c2ccccn2)cc1-c1nnc(NC)s1 +CC1CC1C(=O)N1CCC(c2cc(O)nc(-c3cnccn3)n2)CC1 +COc1ccc(NC(C)=O)c(NS(=O)(=O)c2ccc(C)c(C)c2)c1 +Cc1nn(C)c2[nH]c(=O)c(CCC(=O)N3CCNC(=O)CC3)c(C)c12 +CCCn1c(=O)oc2cc(NS(=O)(=O)c3ccccc3)ccc21 +COC(=O)c1c(CC(=O)Nc2cn[nH]c2)[nH]c(C(C)=O)c1C +COc1cc2c(c(OC)c1OC)C(c1ccccc1)NCC2 +CC(NC(=O)OC(C)(C)C)C(=O)Nc1cn(C)nc1-c1ccncc1 +CCc1ccc(CC(=O)Nc2sccc2C(N)=O)cc1 +C#CCC(OC(=O)c1cccc(OC)c1)c1ccccn1 +CCSc1ccc(NC(=O)Nc2cnn(CC(=O)N(C)C)c2)cn1 +CN1CC(C(=O)NC(C)(C)c2cccc(F)c2)CC1=O +O=C(NCCCn1ccnn1)Nc1ccc(-n2cccn2)nc1 +Cc1cccc(OCC(C)NC(=O)c2nc3nc(C)cc(C)n3n2)c1 +Cc1ccc(OC(=O)CCc2nc(C)no2)c(C)c1 +CCC(O)CN1CCN(C(=O)c2cn[nH]c2C)CC1 +Cc1cccc(C(C)C)c1NC(=O)c1ccc(NS(C)(=O)=O)cc1 +CC(C)N(CCC#N)C(=O)c1cc2ccccc2s1 +COc1cccc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)c1 +COc1ccc(CC(=O)N2CCCC2c2c(C)noc2C)cc1OC +COCC(=O)N1CCCC(C(=O)NCc2cnc(SC)n2C)C1 +Brc1ccc(COCCc2ccccn2)cc1 +CCn1cc(Cl)c(C(=O)Nc2ccccc2Br)n1 +CC(=O)Nc1ccc(F)c(C(=O)NCCC(=O)NC2CCCC2)c1 +Cc1ccc(-c2noc(C(C)n3cc(Cl)cn3)n2)nn1 +CCOC(=O)c1ccc(NC(=O)c2cccc(-n3cnnn3)c2)cc1 +O=C(COc1ccccn1)Nc1ccccc1N1CCCC1=O +O=C(NCCc1cccc(F)c1)C1CC1(Cl)Cl +CCc1cccc2sc(N3CCN(C(=O)c4ccno4)CC3)nc12 +CNC(=O)Nc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cc1 +COc1ccc(C(=O)Nc2nc(S(C)(=O)=O)ns2)cc1OC +O=C(c1ccccc1OCc1ccc(F)cc1)N1CCC1 +NS(=O)(=O)c1cnccc1Sc1cccc(Cl)c1 +CCOC(=O)N1CCc2nc(C(=O)NC(C)C)sc2C1 +Cc1noc(C2CCCN2S(=O)(=O)C(C)C)n1 +CC1CCC(N2C(=O)c3ccccc3S2(=O)=O)CC1 +CCCCC(NC(N)=O)C(=O)NCC(F)(F)F +CC(=O)c1ccc(OCC(=O)Nc2ccc(F)cc2)c(N)c1 +CC(NC(=O)NCc1ncn(C)n1)c1c(Cl)ccc(F)c1Cl +Cc1nc(C2CCCN2C(=O)CCCn2cncn2)no1 +COc1ccc(CCc2nncn2C)cc1Br +CS(=O)(=O)c1ccc(CNC(=O)N(CCO)C2CC2)cc1 +COC(=O)CN(C(=O)c1cnc(-c2ccccc2)s1)C(C)C +CN(CCCO)S(=O)(=O)c1ccc(Cl)cc1 +COc1cccc(OC)c1OCc1cc(N)n(CCO)n1 +Cc1c(C(=O)NCCCC(=O)N2CCCC2)nc2ccc(Cl)cn12 +COCCNC(=O)Cc1ccc(-c2ccccc2)cc1 +CCN(C(=O)CC(C#N)CC(C)C)c1ccccc1 +COc1cccc(N2CC(O)Cn3c2nc2c3c(=O)[nH]c(=O)n2C)c1 +Cc1cc(C(O)C(=O)Nc2ccc(F)c(Cl)c2)ccc1F +CCn1nc(C(=O)NCc2nc3ccccc3[nH]2)c(=O)c2ccccc21 +Cc1csc(C(C)CNC(=O)Nc2cscc2C)n1 +CCOc1cc(NC(=O)N2CCc3cc(F)ccc3C2)ccc1OC +Cn1nc(C2CCN(C(=O)OC(C)(C)C)CC2)c(C#N)c1N +CCC(CC)NC(=O)Cc1c(C)nn(-c2ccccc2)c1C +Cc1nnc(SCC(=O)NCc2cc(CC(C)C)on2)s1 +Cc1ccc(OCC(=O)OCC(=O)Nc2cccc(F)c2)cc1 +OCCOc1ccccc1OCc1ccc(F)cc1 +O=C(CC1CCCC1)N1CCC(c2nnc3n2CCCCC3)CC1 +Cc1ccc(C(C)Nc2ncnc3sccc23)s1 +Cc1ccc(C(=O)N2CCC(CC(N)=O)CC2)c(O)c1 +N#Cc1cc(NC(=O)Cc2cccs2)ccc1O +CC1(C)CC(=O)c2cc(C#N)c(=O)n(-c3ccc(F)cc3)c2C1 +COCCn1cnnc1SCc1coc(-c2cccs2)n1 +CC(Sc1nnc2n1CCCCC2)C(=O)c1c[nH]c2ccccc12 +O=c1[nH]c(NCc2ccco2)nc2nccc(-c3ccccn3)c12 +CCc1cc(N)c2oc(C(=O)NCC(C)C)cc(=O)c2c1 +COc1c(Cl)cccc1NC(=O)CCc1cccnc1 +CCC(c1ccncc1)N(CC)C(=O)Cc1ccc[nH]1 +Cc1ncsc1C(=O)NC(C)C(=O)NCC(F)(F)F +CCCn1cc(-c2ccncc2)cc1C(=O)NCc1ccccc1F +CC(C)c1ccccc1OCCCn1cc(N)cn1 +O=C(CCO)N1CCC(c2[nH]ncc2Cc2ccccc2)CC1 +CC(NC(N)=O)C(=O)Nc1cccc(Cn2cnc3ccccc32)c1 +Cc1ccc(F)cc1NC(=O)NCCCOCC1CCCO1 +Cc1cnccc1NC(=O)c1cnn(-c2ccncc2)c1C +O=C(c1ccn(-c2ccccc2)n1)N1CCN(C2CCCC2O)CC1 +Cc1ccc(CNC(=O)Cn2c(=O)oc3cc(Cl)ccc32)cc1 +CCN(CC)C(=O)CN1CC(C)Nc2cc(C)ccc21 +O=C(COc1cc(Cl)cc(Cl)c1)N(CCO)CCO +Cc1ccc(CNC(=O)CSc2nncn2C)cc1 +O=C(CCn1ccnn1)NCc1ccnc(OC2CCCCC2)c1 +Cc1cccc(Cc2cnc(NC(=O)C(C)n3ccnc3)s2)c1 +CCCc1nnsc1C(=O)NCCc1ccoc1 +CCSc1nnc(NC(=O)CCc2ccc(F)cc2)s1 +CC(C)COc1ccccc1NCCn1nc2ccccn2c1=O +CC1Oc2ccc(C(=O)NC(C)(C)C)cc2N(C)C1=O +COc1ccccc1NC(=O)c1ccc2c(N(C)C)ncnc2c1 +CC(C)(C)OC(=O)NCCCC(=O)Nc1ccccn1 +CC(=O)Nc1ccc(OC(=O)c2csc(-c3ccccn3)n2)cc1 +COC(=O)c1cc(Cl)c(=O)n(Cc2ccccc2)c1 +CN(C)c1ncc(CNCC(O)c2ccc(F)cc2)s1 +Cc1ccoc1C(=O)OCC(=O)c1cc(C)n(-c2nccs2)c1C +COc1cccc(CC(NC(C)=O)C(=O)N2CCOC(C)(C)C2)c1 +CN1Cc2ccccc2CC1C(=O)Nc1cccc(Cl)c1 +CCN(C(=O)c1nc(C(C)C)ncc1Cl)C(C)C +CCOC(=O)c1nc2sc(C(C)(C)C)nn2c1CO +Cc1nn(-c2ccccc2)nc1C(=O)NCc1ccco1 +CCN(CC)c1cc(N)n(-c2ccc(Br)cc2)n1 +O=C(NCCNC(=O)c1scnc1C1CC1)c1ccc(O)cc1 +CCC(c1nnc2n1CCCCC2)n1cc(N)cn1 +Cc1cc(C(=O)Nc2c(C)nn(C)c2C)c2cnn(C)c2n1 +N#Cc1ccc(NC(=O)COC(=O)Cc2ccc(F)cc2)cc1Cl +Cc1cc(S(=O)(=O)NCc2cccs2)cc(N)c1C +Cc1cnn(CC2CN(CC(=O)Nc3nccs3)CCO2)c1 +Cc1cc(C(C)(C)C)cc(C)c1CS(=O)(=O)c1nncn1C +O=C(CSc1ncccn1)NCc1cccc(C(F)(F)F)c1 +COc1cc(C)ccc1OCCN1C(=O)CCS1(=O)=O +O=C(Nc1nnc(Cc2cccs2)o1)c1ccc2c(c1)OCCO2 +CCCC(O)c1cc(Br)cc2c1NC(=O)C2 +CN(CCc1ccccn1)C(=O)COc1ccc2c(c1)CCC(=O)N2 +Cc1nnc2n1CCN(CCC(=O)N1CCc3sccc3C1)C2 +O=C(c1ccc(NC2CC2)nc1)N1CCOC2CCCC21 +NC(=O)c1cc(S(=O)(=O)Nc2ccccc2Cl)cs1 +Cc1nc(COc2ccc(NC(=O)C3CCCC3)cc2)no1 +CC(C)(C)OC(=O)N1CCC2(Cc3ccccc3NC2=O)C1 +CCn1c(C2CCN(C(=O)Nc3ccccc3)C2)nc2cccnc21 +Cc1nc(-c2nnc(NC(=O)c3cccnc3)o2)cs1 +CCCc1ccc(C(=O)Nc2ccc3c(c2)C(=O)N(C)CCO3)cc1 +Nc1cc(Br)cc2c(C(=O)NC3CC3)nccc12 +COc1cc2c(c(Br)c1O)C(O)CNC2 +CCCCCOc1cccc2c1CCNC2CNC(C)=O +Cc1cc(C(=O)NC2CCCCCC2)ccc1N(C)S(C)(=O)=O +CC(=O)Nc1cc(NC(=O)c2sccc2C)ccc1F +CC(=O)Nc1cccc(OCC#CCNC(=O)c2ccc(C#N)cc2)c1 +Cc1cc(CN2CCN(C(=O)NCCNc3ncccn3)CC2)on1 +N#Cc1cccc(CNC(=O)NCc2ncc(-c3ccccc3)o2)c1 +CCc1nnc(COc2ccc(CO)cc2Br)o1 +COC(=O)c1ccc2ccn(CC3CCCCO3)c(=O)c2c1 +Cc1c(C(=O)NC2(c3ccc(Cl)c(Cl)c3)CC2)cnn1C +CC1CN(c2ccccc2NC(=O)NC2CC2)CC(C)O1 +C=CCN(CC=C)C(=O)c1cccc(NC(=O)C(C)C)c1 +COc1cccc(C(N)=O)c1OCC(=O)Nc1cccc(C)c1 +Cc1c(O)cccc1C(=O)N1CCCC2(CCC(=O)N(C3CC3)C2)C1 +COc1cc(CNc2cccnc2)cc(Cl)c1O +CCN(CC)C(=O)Cn1c(=O)n(C)c(=O)c2sccc21 +CCc1nnc(NC(=O)c2c(C)noc2C)s1 +Cn1cncc1C1NCCc2cc(OC(F)F)ccc21 +Cn1cc(S(=O)(=O)NCc2ccccc2)c(=O)n(C)c1=O +CC(C)CCNC(=O)C(N)c1ccc2c(c1)OCO2 +CCCC(=O)NCC(=O)Nc1cc(-n2cccc2)ccc1F +Cc1c(F)cccc1-c1ccc(CN2CCN(C(=O)C(C)O)CC2)o1 +CC(C)(C)NC(=O)c1ncc(-c2ccc(F)cc2)o1 +Cc1cnc(C)c(N(C)Cc2csc(C(C)C)n2)n1 +COc1ccc(CNC(=O)C(C)Sc2ccccn2)cn1 +CSc1nnc(CSc2nc(-c3cccs3)n[nH]2)s1 +CC(Oc1cccc(N)c1)C(=O)N1CCOCC1 +COc1ccccc1CNC(=O)CNc1cc(NC(C)=O)ccc1C +Cn1c(=O)c2c(nc3n2CCN3CCO)n(C)c1=O +O=C(NCc1cc(-c2ccco2)on1)c1nc2ccccc2s1 +O=C(CCNC(=O)c1ccoc1)NCc1ccccc1Cl +O=C(C1CCCCN1S(=O)(=O)c1ccccc1)N1CCCC1 +COCCn1c(SCC(N)=O)nc2ccccc21 +CS(=O)c1ccc(C(=O)OCC(=O)N2CCCCCC2)cc1 +CCc1nc(C)ccc1OCc1nc(-c2cccnn2)no1 +COc1cc(C(=O)NCc2ccccn2)ccc1N +CNc1nc(Nc2cccc(OC)c2)c2cnn(C)c2n1 +CC1CCN(C(=O)c2cccc(NC(=O)C(C)C)c2)CC1 +Cn1ccsc1=NC(=O)Cn1nc2ccccn2c1=O +Cc1nc(NCc2snnc2C)cc(C2COCCN2)n1 +CC(C)c1nc(Cc2ccc(Br)cc2)n(C)n1 +CCC(C)C(NC(=O)c1cccc(NC(=O)C2CC2)c1)C(N)=O +CC1(C)CCN(S(=O)(=O)c2ccc(O)c(N)c2)CC1 +CNC(=O)CSc1nnc(COc2ccc(C(C)(C)C)cc2)n1N +CC(Cc1ccco1)NC(=O)NCc1cccnc1OC(C)C +CC(CC(N)=O)C(=O)Nc1ccc(Cl)cc1C(F)(F)F +CC(=O)Nc1ccc(S(=O)(=O)NCc2ccccc2C)cc1 +Cn1cnnc1-c1ccc(NC(=O)CCc2ccsc2)cc1 +COc1ccc(NC(=O)c2onc(C#N)c2N)c(OC)c1 +O=C(NCCCC(=O)N1CCN(c2ncccn2)CC1)C1CC1 +CC(=O)c1cccc(OCC(=O)N(Cc2cccc(C)c2)C2CC2)c1 +O=C(Cc1ccc[nH]1)Nc1ccccc1SC(F)F +C#CCN(Cc1ccco1)S(=O)(=O)c1cnn(C)c1 +COCc1nc(C)c(C(=O)N=c2[nH]cc(C)[nH]2)s1 +CN(C(=O)c1cccc2cccnc12)C1CCCCC1 +Cn1cc(NC(=O)CCCc2cc(F)ccc2F)cc(Cl)c1=O +Cc1cn(S(=O)(=O)c2ccc(Cl)cc2)cn1 +CCOc1c(O)c(Cl)cc2c1C(CC)NCC2 +CCN(CCNC(=O)COC)c1ccccc1C +CC(NC(=O)CNC(=O)Cc1ccccc1)c1ccccc1Cl +Cc1nc(SCC(=O)OCc2ccccc2)[nH]c(=O)c1C +CS(=O)(=O)N1Cc2nccn2CC(Cn2ncccc2=O)C1 +CCNC(=O)COc1ccc(NC(=O)c2ccc(=O)n(C)c2)cc1 +N#Cc1ccc(S(=O)(=O)Nc2cnn(C3CCOCC3)c2)cc1 +CN(C(=O)c1c(-c2ccncc2)cnnc1N)c1ccccc1 +Nc1ccc(NC(=O)Cn2cc(Cl)cn2)c(Br)c1 +CCn1nc(CCOC)nc1-c1ccc(N(C)S(C)(=O)=O)cc1 +O=S(=O)(NCC(O)(c1cccs1)C1CC1)c1ccc(F)cc1 +CCOc1ccc(NC(=O)CC(c2ccco2)n2cccc2)cc1 +CCCCn1nc(C(=O)N2CCNC(=O)CC2)c2ccccc2c1=O +CCS(=O)(=O)NCC(c1ccc(Cl)cc1)N1CCOCC1 +CC(=O)N(C)CC(=O)NCc1ccnc(OC2CCCCC2)c1 +NC(=O)Cc1cccc(OC(=O)CN2CCCCCC2=O)c1 +O=C(NCc1ccccc1F)N1CCN(Cc2ccccc2)CC1 +COc1ccccc1COC(=O)c1ncn(-c2ccccc2)n1 +O=C(OCc1nncn1C1CC1)C1(c2ccccc2)CC1 +Cc1cc(CC2COCC2NC(=O)c2cnc(NC(C)C)nc2)on1 +Nc1ccc2c(c1)N(CC(=O)Nc1ccccc1F)CCO2 +CCC1CCCCN1C(=O)c1snc(C#N)c1N +CCCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccccn1 +Cc1cc(C(=O)NCC2(c3ccc(F)cc3)CCCC2)on1 +CC1(C)Cc2occc2C(NC(=O)c2ccc(F)cc2)C1 +Cc1ccc(C(=O)NCCNC(=O)Nc2c(C)cccc2C)cc1F +CC(C)CC(=O)Nc1ccc(CSc2ncn[nH]2)cc1 +COCCCCCNC(=O)Nc1ccc2nc(C)sc2c1 +Cc1cc(-c2cc(=O)n(CC(=O)NC3CCCC3)nc2C(C)C)on1 +Cc1cccc(OCCN2CCN(S(C)(=O)=O)CC2)c1 +COC(=O)c1ccc2c(-c3ccoc3)ccnc2c1 +Cc1cc(CC(C)NC(=O)Nc2ccc3c(c2)OCCO3)[nH]n1 +COCc1nc(COc2ccc(C)cc2C)sc1CC#N +CCOCCCNC(=O)NC1CCC(CC)CC1 +Cc1nc(CNc2cc(C(=O)NCC(F)(F)F)cc(F)c2C)no1 +CCOc1ccc(S(=O)(=O)N2CCOCC2)cc1Cl +COc1ccccc1C(O)CNc1cc(C)nc(C)n1 +O=C(c1ccco1)N1CCN(c2nc3c(F)cc(F)cc3s2)CC1 +Cc1c(C(F)(F)F)n[nH]c1NC(=O)Cn1cccn1 +CC(=O)N(C)Cc1cccc(NC(=O)NC2CCCCCC2)c1 +CC(C)C(CNC(=O)c1ccc(C#N)cc1)N1CCOCC1 +CCOc1cc(C)ccc1NC(=O)CCn1c(C)csc1=O +Cc1nc2c(c(=O)n1CC(=O)Nc1cccc(Cl)c1F)CCCC2 +CCOc1ccc(N2CC(NC(=O)C3CCCC3)CC2=O)cc1 +CCC(NC(=O)c1cc2ccccc2c(=O)[nH]1)c1ccccc1OC +Cc1cccc(CNC(=O)c2nc(C)n(-c3ccc(F)cc3)n2)c1 +COC(=O)CCCN(C)C(=O)c1cnn(-c2ccc(F)cc2)n1 +COC(=O)Nc1ccc(CNC(=O)c2cccc(OC)c2OC)cc1 +CCC(CC)c1nnc(NC(=O)C2CC=CC2)s1 +Cc1ccc(NC(=O)CSc2ccccc2)cc1N +COC(=O)c1cc(NCc2cnn(C)c2)ccc1F +CC(C)(C)OC(=O)C(C)(C)S(=O)(=O)c1ccc(Cl)cc1 +O=C(CSc1cc(N2CCCC2)ncn1)OCc1ccccc1 +COC1CCCC1OC(=O)c1ccc(C)c(NC(C)=O)c1 +O=C1CC(c2c(O)cccc2O)Oc2cc(O)cc(O)c21 +COC(=O)c1cnc(NC(=O)Cc2ccc3ccccc3c2)s1 +Cc1cc(C)nc(NC(=O)N2CCC(C(=O)N(C)C)CC2)c1 +COc1cc(C(=O)Nc2ccc(C#N)c(C#N)c2)ccc1Cl +Cc1cc(CN2CNc3cccc(Cl)c3C2=O)[nH]n1 +O=C(NCCn1cnc2ccccc21)c1cc2ccccn2n1 +CC(=O)Nc1cccc(NC(=O)c2cn3cc(C)ccc3n2)c1 +CCCCNC(=O)Cn1nnn(-c2cccs2)c1=O +C#CCN1CCN(C(=O)NC(C)c2ccc3c(c2)OCCO3)CC1 +CNS(=O)(=O)c1cccc(CNC(=O)c2ccc(C)c(C)c2O)c1 +CC(NC(=O)c1cnccn1)c1nc(-c2ccc(Cl)cc2)no1 +CC1CC1C(=O)Nc1cccc(C(=O)N2CCC(CO)CC2)c1 +Cn1c(=O)n(CC(=O)N2CCC(CC(N)=O)CC2)c2ccccc21 +COC(=O)C1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 +O=C(COC(=O)CCc1ccc(F)cc1)NC1CCCCC1 +Cc1nc(OCC(=O)NC2CCCCC2C)c2ccccc2n1 +CC(=O)Nc1ccc(OC(=O)c2nn(C)c3ccccc3c2=O)cc1 +CCOc1ccnc(N2CCC(O)(c3ccccc3)CC2)n1 +Cc1csc(=O)n1CC(=O)NC1CCC(C)CC1 +CCCn1nc(C)c(CNC(=O)CSc2nnc(C)s2)c1C +O=C(OCCn1nc2ccccn2c1=O)C1CCCC1 +Cc1oc(-c2cccs2)nc1CC(=O)NCCc1ccccc1 +CCN(CC)C(C(=O)Nc1nncs1)c1ccccc1 +C#CCN1CCN(Cc2nc(-c3ccc(C(C)C)cc3)no2)CC1 +O=C(Cn1ccn(-c2cccc(Cl)c2)c1=O)Nc1ccccc1 +Cc1noc(C)c1C(=O)NCc1coc(-c2cccs2)n1 +COCc1cc(CN(C)C(=O)CCc2scnc2C)n[nH]1 +COC(=O)NCC(=O)Oc1cc(C)cc(C)c1C +Cc1cc(N2CCN(C(=O)c3ccccn3)CC2)nc2nnc(C)n12 +CNC(=O)c1ccsc1NC(=O)c1cc(Cl)ccc1OC +O=C1NCCCCC1NC(=O)N1CCc2ccccc21 +CN(C)S(=O)(=O)c1ccc(CNc2ncccc2F)s1 +COc1cc(C)c(-c2cc(=O)[nH]c(=O)[nH]2)cc1C(C)C +O=C(NCc1ccnc(OC2CCC2)c1)C1(c2cccc(F)c2)CC1 +CC(C)(C)OC(=O)CCN1CCN(C(=O)c2cc(Cl)c[nH]2)CC1 +Cc1ccc2ncc(C(=O)N3CCN(C4CCCCC4)CC3)n2c1 +CCCn1c(=O)[nH]c(=O)c2[nH]c(NCCCO)nc21 +CCCn1ncc(C(=O)NCc2ccc(-n3cccn3)cc2)c1C +O=C(CN1CCN(c2ncccn2)CC1)NC1CCCCC1 +CC(=O)c1ccc(NC(=O)CN(C(C)=O)c2ccccc2)cc1 +CC(Cc1ccccc1F)NC(=O)c1cnn(C(C)(C)C)c1 +CCN(CCc1nccs1)C(=O)c1ccc(-n2ccnn2)cc1 +O=C(NCc1ccco1)Nc1nc(-c2cccs2)ns1 +Cc1cc(C(=O)N2CCC(N3CCOCC3)C(CCCO)C2)[nH]n1 +Cc1c(C(=O)NCc2ccccn2)sc2nc[nH]c(=O)c12 +Cc1nnc(-c2c(C)[nH]c(C)c2S(=O)(=O)NCC2CCCO2)o1 +CCC(C(=O)Nc1nc(C)cs1)n1c(C)cc(C)nc1=O +CCNC(=O)COc1cccc(NC(=O)Nc2cccnc2)c1 +COC(=O)c1cccc(CCNC(=O)c2cscc2C)c1 +CCc1ccc(C(=O)N2CCCC2c2ccccn2)o1 +CCc1ccc(C(C)NC(=O)CN2CCN(CC(N)=O)CC2)cc1 +Cc1ncc(CNC(=O)C2CC2c2ccccc2)s1 +Cc1cc(NC(=O)CCCc2nc(-c3cccs3)no2)no1 +CCN(C(=O)c1cc(NC)ccn1)C(C)COC +Cc1ccc2ncc(C(=O)N3CCN(Cc4cc(C)on4)CC3)n2c1 +Cc1ccc(C(=O)NCCN2CCCCCC2=O)c(=O)[nH]1 +CCc1onc(C)c1NC(=O)NCC(C)Cc1ccc(OC)cc1 +O=C(NCc1ccncc1)c1cc2ccc(Cl)cc2[nH]1 +CCc1ccccc1NC(=O)CNc1nccc2c1C(=O)OC2(C)C +COc1ccc2c(c1)C(C(O)c1ccc(O)cc1)NCC2 +N#CCOc1cc(F)ccc1NC(=O)c1cnc(C2CCCO2)s1 +O=C(Cc1noc2ccccc12)Nc1nccs1 +CC(=O)OCC(=O)Nc1ccc(-c2ccccc2)cc1 +CCCn1nnnc1Cn1cnc2c(Cl)cc(Cl)cc2c1=O +Cc1ccc(C(=O)CCC(=O)N2CCCC2)c(C)c1 +Cc1noc(COc2ccc(F)cc2Br)n1 +CCc1nc2sc(C(=O)Nc3ccccc3C)c(C)c2c(=O)[nH]1 +N#Cc1cccc(NC(=O)CNc2ccc(F)cc2)c1 +CC(Oc1ccc(-n2cnnn2)cc1)C(=O)NC(C)c1ccccc1 +Cc1ncsc1C(=O)Nc1ccc(-n2ccnc2)c(Cl)c1 +C#CCC(C)C(=O)c1ccc2c(c1)N(C)C(=O)CO2 +CC(=O)N1CCc2nc(-c3cccnc3)nc(N3CCCCC3)c2C1 +Cn1nncc1CNc1ccc(Sc2cccs2)cn1 +Cn1cc(NC(=O)NCCCN2CCOCC2)c2ccccc21 +CC(=O)Nc1ccc(C(=O)c2ccc(F)cc2)c(O)c1 +COc1ccc2c(C)c(C(=O)NCCSc3nnnn3C)oc2c1 +CC(C)(CO)NC(=O)C1(c2cc(-c3ccc(Cl)cc3)on2)CC1 +CCOC(=O)c1nnsc1NC(=O)Oc1ccccc1 +CCOC(=O)NCC(O)c1ccc(C(F)(F)F)cc1 +CCCc1ccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)NCC3)cc1 +CC(OCC1CCCCO1)C(=O)N1c2ccnn2C(C)CC1C +CCCCN(C)C(=O)Cc1c(C)nc(C)[nH]c1=O +CCc1cnc(C(C)Nc2ncnc3[nH]cnc23)s1 +COCC(O)CN(C)S(=O)(=O)c1cc(F)cc(F)c1 +CC(C)CC(CO)NC(=O)NCC#Cc1ccccc1 +Cc1nc2sccn2c(=O)c1NC(=O)Cc1ccccc1Cl +CC(C)c1nnc(NC(=O)Nc2cccc(Cl)c2)s1 +O=C(Nc1nc[nH]n1)c1cnn(-c2ccc(F)cc2)c1-n1cccc1 +O=C(CSc1ccc(O)cc1)Nc1ccc(F)cc1Cl +Cn1ncnc1CNc1ccc(SC(F)F)cc1 +CSc1ccc(NC(=O)Cc2ccc(S(C)(=O)=O)cc2)cc1 +O=C(CCc1nc(-c2cccnc2)no1)NCc1ccccc1Cl +CCc1nn(C)c(CC)c1CNC(=O)c1cccc(-c2ccoc2)c1 +COc1ccc2c(c1)OCC(CNC(=O)CCCN1CCCC1=O)C2 +CCn1cc(CNC(=O)c2nc(-c3cccs3)no2)cn1 +CSc1cccc(NC(=O)C2CC(=O)Nc3ccccc32)c1 +COc1ccc(C(N)=O)c(OCC(=O)Nc2cccc(Cl)c2)c1 +O=C(CNc1ccc(F)c(Cl)c1)N1CCN(c2ccccc2)CC1 +O=c1[nH]n(-c2cccc(Cl)c2)c(=O)c2ccccc12 +CC1CCc2c(sc(NC(=O)c3ccnn3C)c2C(N)=O)C1 +CS(=O)c1ccccc1NC(=O)NCCCn1cccn1 +CCN(C(=O)c1cnc(N(C)C)nc1C)C1COCC1O +Cc1ccc(NC2C(=O)Nc3ccc(Cl)cc32)cc1 +O=C(CO)N1CCN(C(=O)c2cccs2)CC1 +CC1CN(Cc2csc(C(C)C)n2)CC(c2ccccc2)O1 +O=c1oc2ccccc2n1Cc1coc(-c2ccccc2)n1 +C#Cc1cccc(NC(=O)CNC(=O)NC(C)C)c1 +CCOc1cccc(CCC(=O)N(C)CCO)c1 +Cc1noc(C)c1C(C)C(=O)OCCNc1cccnn1 +CC(NC(C)c1ccc(Cl)cc1)C(=O)Nc1ccc(C(N)=O)cc1 +CCc1ccccc1NC(=O)c1nnn(-c2ccccc2C)c1N +Cc1cccc(S(=O)CC(=O)NCCOc2ccc(F)cc2)c1 +CCOc1ccc(-n2nnnc2CNC(=O)Nc2ccccc2)cc1 +CC(C)NC(=O)c1ccnc(-c2ccncc2F)c1 +CCOC(=O)Cn1ccc(=O)c2cc(Br)ccc21 +COCCCNC(=O)Cn1nnc(-c2ccccc2C)n1 +COc1ccc(-c2cc(CC3CCN(C(C)=O)CC3)ccn2)cc1 +O=C(Nc1ccc(Oc2cccnc2)cc1)N1CCCCC1CO +CCC1CN(C(=O)Cc2cn3ccccc3n2)CC1N1CCOCC1 +CCOc1ccc2c(c1)CN(C(=O)c1cc(=O)c3ccccc3o1)CC2 +CC(C(=O)Nc1cc(F)ccc1OCC1CCCO1)c1ccsc1 +CSc1cc(C(=O)Nc2cccc(-n3cnnc3)c2)ccn1 +CC(CNC(=O)Cc1ccc(F)cc1F)Cn1cccn1 +NS(=O)(=O)CCNC(=O)c1cncc(Br)c1 +CCCOC(=O)CN1C(=O)C(C)(C)Cc2ccc(N)cc21 +CCn1c(SCC(=O)Nc2cc(C)on2)nc2ncccc2c1=O +CCc1[nH]c(SCC(=O)Nc2nc3ccccc3s2)nc1C +Cn1ncc2c1CN(C(=O)c1ccc(-c3ccsc3)o1)C2 +COc1ccc(C(=O)CN2C=NS(=O)(=O)c3ccccc32)cc1 +CC(C)C(Sc1nnnn1C)C(=O)Nc1ccc2c(c1)CCC2 +COC(=O)C(C#N)c1nc2ccccc2nc1NC1CCCC1 +Cc1ncsc1CN1CCN(C(C)c2ccc(F)cc2F)CC1 +CCNC(=O)NC1(C(=O)NCC2(C)CCCC2)CCCC1 +CCc1noc(-c2cccn2Cc2cccc(OC)c2)n1 +O=C1CCC2(CCCO2)CCN1Cc1ccccc1OC(F)(F)F +O=C(NCC12COCC1CN(c1ncc(F)cn1)C2)c1ccccc1 +Cc1ccc(-n2nnnc2SCCc2ccncc2)cc1 +Cc1c(-c2cccnc2)nn(-c2ccccn2)c1N +CCOC(=O)Cn1cccc(NC(=O)N2CC(C)CCC2C)c1=O +Cc1noc(C2CC2)c1NC(=O)Nc1ccc(S(C)=O)cc1 +COc1ccccc1-c1cc(C(=O)NCC2CC2)n(C)n1 +Cc1cccc(C)c1NC(=O)Cn1c(=O)sc2cccc(Cl)c21 +COc1ccc(O)c(C(=O)OCC(=O)NC(C)(C)C)c1 +Cc1cc(F)ccc1CNc1cccc(-n2cnnn2)c1 +CC(C(=O)NCCc1ccccc1)n1c(N)nnc1SCC#N +N#CCCCn1c(-c2ccccc2)nc2cc(Cl)cnc21 +O=C(Nc1ncccc1O)c1cnn(Cc2ccccc2Cl)c1 +COc1ccc2c(N3CC(C)OC(C)C3)ncnc2c1OC +Cc1ccc2ncc(C(=O)N3CCCC(CC(N)=O)C3)n2c1 +Cc1ccc(C(=O)Nc2cc(F)ccc2OCC2CCCO2)c(C)n1 +O=c1oc2ccccc2n1Cc1noc(-c2ccc(Cl)cc2)n1 +Cc1cnc(NC(=O)c2ccc(NC3CC3)nc2)s1 +CS(=O)(=O)NC1CCN(Cc2ccc(F)cc2C(F)(F)F)C1 +CCNC(=O)CN1CCN(C(=O)c2ccc(C)c(C)c2O)CC1 +CCc1oc(C(C)C)cc1-c1nnc(NCCOC)s1 +O=C(Nc1ccc(CC(=O)N2CCCC2)cc1)NC1CCCCC1 +CC(C)N(C)S(=O)(=O)NC1(C#N)CCCCCC1 +CCn1nc(C)c(NC(=O)c2ncoc2-c2ccc(F)cc2)c1C +COc1ccc(OC)c(-c2csc(NC(=O)c3cc(C)on3)n2)c1 +CC(C)N1CC(C(=O)N(C)Cc2nc3ccsc3c(=O)[nH]2)CC1=O +COc1cc(-c2nc3ccc(N)cc3o2)cc(OC)c1OC +COC(=O)c1cc(NC(=O)CNC(=O)c2cc(C)n(C)n2)ccc1C +CCOc1ccc(CN(C(C)=O)c2cccc(N)c2)cc1 +CC(C)N(C)C(=O)C1CCN(C(=O)Nc2cccc(F)c2)CC1 +Cc1ccc(OCC(=O)NCCc2nc3ccccc3[nH]2)cc1C +CNC(=O)c1cccc(CCNC(=O)Cc2ccc[nH]2)c1 +COC(=O)c1c(C)[nH]c(C(=O)N2CCN(C(=O)C(C)C)CC2)c1C +CCCNC(=O)C1CCN(c2nc3ccc(OC)cc3s2)CC1 +CCC(C)N(C)C(=O)NCCc1ccc(OC)c(OC)c1 +Cc1ncc(CNC(=O)Nc2ccc(Cl)cc2Cl)s1 +CCc1cc(=O)oc2cc(OS(=O)(=O)c3c(C)noc3C)ccc12 +Cn1cccc1C(=O)OCc1nc2ccccc2o1 +NS(=O)(=O)CCCNC(=O)c1cc2ccccc2o1 +Clc1ccc(Cl)c(NCc2ccccn2)c1 +N#Cc1ccc(NC(=O)c2cccc(F)c2F)cc1 +Cc1cc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)on1 +CCc1noc(CSc2nc(-c3ccc(C)cc3)n[nH]2)n1 +C#CCN1CCN(C(=O)CNS(=O)(=O)c2cn(C)cn2)CC1 +CCN(CCC(=O)OC)C(=O)Cn1c(=O)oc2ccccc21 +Cc1ccc(S(=O)(=O)NCCC(O)c2cccs2)s1 +N#CC(CC(=O)NCc1ccncc1)c1ccccc1Cl +C=CCOc1ccc(C(=O)N2CCN(CCO)CC2)cc1OC +NS(=O)(=O)c1cc(C(=O)Nc2ccccc2)cs1 +CCOc1c(C)cc(S(=O)(=O)N2CCN(C)CC2)c(C)c1C +Cc1cc2c(cnc3ncnn32)c(=O)n1-c1ccc(Cl)c(Cl)c1 +CC1CN(CC(=O)NCC(C)n2cncn2)CC(C)O1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)N2CCC(C)CC2)cc1C +COC(=O)c1ccccc1NC(=O)c1ccc(N2CCOCC2)cc1 +COc1ccc(-c2c(CO)nnn2Cc2ccccc2F)cc1 +Cc1cc(N2CCCC2c2cc(Nc3cnccn3)nc(C)n2)ncn1 +CC1CCCCC1NC(=O)NC1CCN(S(C)(=O)=O)CC1 +COc1ccc2c(c1)CCCN2C(=O)COn1nnc2ccccc21 +CCCC1CN(C(=O)c2cc(C)nc3ccc(OC)cc23)CCO1 +CC(Sc1nnnn1-c1ccccc1)C(=O)Nc1ccc(F)cc1 +Cc1cccc(NC(=O)c2ccc(N3CCOCC3)cc2)c1 +Cc1ccoc1C(=O)Nc1ccc(CC(=O)N(C)C)cc1 +N#CCCN(Cc1cccc2c1OCCCO2)CC1CC1 +Cc1cccc(CNC(C#N)c2ccc(F)cc2)c1 +Cc1ccc(SCCNC(=O)CCc2c(C)nc(C)[nH]c2=O)cc1 +O=C1CC(C(=O)N2CCOCC2C2CC2)CN1C1CCCCCC1 +NC(=O)C1CCN(C(=O)CCOc2cccc(Cl)c2)CC1 +COc1cc(N)c2c(C(=O)NCCCO)nccc2c1OC +CC(C)CC(C)(NC(=O)c1cccc(-n2cccn2)n1)C(N)=O +O=C(Cc1cccc(F)c1)Oc1ccc(-n2cnnn2)cc1 +Cc1csc(CCNc2cc(=O)n3ccccc3n2)n1 +COc1ccc(C2(C(=O)N3CCCCC3)CCOCC2)cc1 +COc1ccc(OC)c(S(=O)(=O)NCc2cn3ccccc3n2)c1 +O=S(=O)(NC(CO)c1ccccc1)c1cccc2ncccc12 +Cc1ccc(C)c(OCc2nn3c(C#N)c(C)nc3s2)c1 +Cc1ccc(CNC(=O)CN2CCN(c3c(C)n[nH]c3C)CC2)cc1 +O=C(Cc1ccsc1)Nc1ccc(Sc2nncs2)cc1 +Cc1noc(N)c1C(=O)OCc1ccc(C(F)(F)F)cc1 +Cc1nnc(SCC(=O)NCc2ccccc2)c2ccccc12 +Cc1ccoc1C(=O)NC1CCC(n2cnnc2)CC1 +O=C(c1cscn1)N1CCC(Nc2cccnn2)CC1 +O=C(NCCO)NCc1ccc(OCc2cccnc2)cc1 +Cc1ccc(Cn2nccc2NC(=O)CSc2ccc(F)cc2)o1 +COC(=O)CNC(=O)c1c[nH]nc1-c1ccccc1Cl +Cc1cccc(OCC(=O)NCCc2n[nH]c(C)n2)c1 +CN1C(=O)CC(C(=O)NCCc2cccs2)C1c1cccnc1 +CC(C)NC(=O)COC(=O)c1cccc(NC(=O)C2CC2)c1 +Cc1c(Br)cc(Br)c(=O)n1C +N#Cc1ccc(NC(=O)c2ccn(-c3cccc(Cl)c3)n2)cc1 +O=C(NCCCNC(=O)c1cccs1)c1cnc2snnc2c1 +O=C(CCCc1cccs1)NCc1ccccn1 +O=C(C1CCC1)N(Cc1cccnc1)c1nc2ccccc2s1 +CC(=O)Nc1cc(NCc2cn[nH]c2-c2cccc(C)c2)ccc1F +CSc1ccc(-c2csc(CC(=O)NCc3ccco3)n2)cc1 +Cc1n[nH]c2ncc(CNC(CN3CCCC3=O)c3ccccc3)cc12 +CC(C)NC(=O)c1coc(NC(=O)c2ccco2)n1 +CC(C)C(C)N(C(=O)NCc1ccc(-n2cncn2)cc1)C1CC1 +CCOC(=O)c1cccc2cnn(C3CCCC3)c12 +N#Cc1cccc(C(=O)NCC2CCN(c3ncccn3)CC2)c1 +O=c1c2cccnc2ncn1Cc1ccc(F)cc1 +CC1(NC(=O)c2cccc(NC(=O)NC3CC3)c2)Cc2ccccc2C1 +CC(C)(CNC(=O)NCC1(c2ccc(F)cc2F)CC1)C(N)=O +OC(COc1cccc2ccccc12)CN1CCOCC1C1CC1 +COc1ccccc1OC(=O)c1cccc(-n2cnnn2)c1 +CN1CC(C(=O)N2CCc3c(F)ccc(F)c3C2)CC1=O +Cc1nc(CNC(=O)c2cc3c(s2)CCC3)c(C)s1 +O=C(Nc1ccc2[nH]ccc2c1)c1ccc(-n2ccnn2)cc1 +COc1cccc(S(=O)(=O)N2CCN(CCC(C)C)CC2)c1 +Cc1csc(CN(C)C(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)n1 +CCOC(=O)Cc1csc(NC(=O)c2cc(N)ccn2)n1 +CCN(Cc1ccccc1)C(=O)c1cnc(N)c(Cl)c1 +CCc1ccc(CNC(=O)Nc2ccc(CC(=O)NC)cc2)s1 +COc1ccc(OC)c(CC(=O)N(C)c2cccc3ncccc23)c1 +Cc1nc2c(cc1C(=O)Nc1ccccc1)c(=O)n(C)c(=O)n2C +O=C(Nc1ccc(F)cc1)C1CC(=O)N(C2CCCC2)C1 +O=C(CCCNC(=O)c1ccc(F)cc1F)Nc1cccnc1 +CCOC(=O)Nc1cccc(NC(=O)OCC)c1 +O=C(CCNC(=O)c1cnn2c1SCC2)NCc1cccs1 +CC(Sc1ncn[nH]1)C(=O)N1CCCc2ccccc21 +COc1cccc(OCC(=O)N2CCc3ccccc32)c1OC +CC(=O)Nc1cc(S(=O)(=O)N2Cc3ccccc3C2)ccc1F +NC(=O)c1ccc(CNC(=O)Nc2cnn(-c3ccccc3F)c2)o1 +CCCCNC(=O)C1CCCN(S(=O)(=O)c2cnn(C)c2)C1 +O=C(CCCc1nc(C2CC2)no1)NC1(c2ccccc2)CCCC1 +O=C(NCc1cccnc1)c1ccc(OCC(F)F)nc1 +CCCCCNC(=O)C(C)(c1ccccc1)N(C)C +COc1ccc(S(=O)(=O)NCCc2ccoc2)cc1Cl +CCCC1(CO)CCCN(C(=O)Cn2cc(C)cn2)C1 +c1ccc(COCC2CCCC23CN(c2ncccn2)CCO3)nc1 +CC(NC1CCCc2ccccc21)C(=O)N1CCCc2ccccc21 +O=C(NCCO)c1ccc(-c2cccc(Cl)c2Cl)o1 +CCCCN(CCO)C(=O)c1cc(F)ccc1C +CC(C)N(CC1CC1)c1cc2c(cc1N)CC(=O)N2 +Cc1cccc(CN(C(=O)CCC2CCCO2)C2CC2)c1 +CC(C)Oc1cncc(OC(C)C)c1OC1CC1 +C#CCN1CCN(C(=O)Nc2ccc(C)cc2)CC1 +CC(C)(C)NC(=O)CNC(=O)Nc1ccc(OC(F)F)c(F)c1 +CCOCCCNC(=O)c1cccc(OC)c1O +CC1CC1C(=O)N1CCN(Cc2noc(-c3cccs3)n2)CC1 +N#Cc1cccc(NC(=O)CCn2cc(Cl)cn2)c1 +CCC(OC1CCCC1)C(=O)Nc1cnn(-c2ccccc2F)c1 +CC(=O)N(c1nc(CNc2cc(F)ccc2F)cs1)C1CC1 +CC(C)(C)OC(=O)N1CCCC(CCCOc2ncccc2O)C1 +COc1ccc(C)cc1C1(CNS(N)(=O)=O)CCOCC1 +CCOc1cccc(NCc2csc(N(C(C)=O)C3CC3)n2)c1 +O=C(Nc1ccc(-n2cccn2)nc1)c1cn(-c2ccc(F)cc2)nn1 +CC1CCCC(C)N1C(=O)Cn1c(=O)cnc2ccccc21 +N#Cc1ccsc1NC(=O)c1ccnc(OCC(F)F)c1 +CCOc1ccc(OCC(O)Cn2ncc3ccccc3c2=O)cc1 +Cc1nc2ccc(O)cc2c(=O)n1CC(=O)Nc1ccc2cc[nH]c2c1 +CC1CCC(N(C)C(=O)Cn2cnc3cc(F)c(F)cc32)CC1 +O=C(Nc1cccc(C(=O)C2CC2)c1)c1cccnc1 +CCOC(=O)CSc1nnc(-c2ccc(F)cc2)n1N +O=C(C1CC1)N1CCCC1c1nc(-c2ccc(F)cc2)n[nH]1 +CCC(NC(=O)c1ccc(-n2cncn2)cc1)c1cc(F)ccc1F +OCCC#Cc1c(OC(F)F)ccc2ccccc12 +COc1ccc(OC)c(C(=O)N(C)CC(=O)NCc2ccco2)c1 +CC(=O)Nc1cccc(NC(C)C(=O)NC(C)(C)C)c1 +O=C(NCc1nnnn1C1CC1)NC1CCCCc2ccccc21 +Cc1ccc(F)cc1NC(=O)NCCC(=O)N(C)C +COc1ccccc1CNC(=O)NCC(O)C(F)(F)F +Cc1noc(C)c1COc1cccc(C(=O)N2CCOCC2(C)C)c1 +C=CCN(Cc1c[nH]nc1-c1ccc(F)cc1)CC(F)(F)F +CCOC(=O)c1sc(S(C)=O)c2c1CCCC2=O +O=C(NCCOCC(F)(F)F)c1ccc(Br)cc1 +CC(C)(C)OC(=O)N1CC=C(n2c(=O)[nH]c3ccccc32)CC1 +CCC(C(=O)Nc1ccc(NC(C)=O)cc1)c1ccccc1 +COCCN(Cc1ccco1)C(=O)c1cccc(C#N)c1 +COc1ccc(S(=O)(=O)N2CC(C)OC(C)C2)cc1F +Cc1cnn(CC(=O)NC2CCc3c(O)cccc32)c1 +CC(C)NC(=O)Nc1cccc(NC(=O)c2cnccn2)c1 +COc1ccc(NC(=O)N(Cc2ccsc2)C2CC2)cc1 +O=C(NCCCNC(=O)c1nc2ccccc2s1)c1cccnc1 +O=C(Cc1c[nH]c2ccccc12)NCC#CCOc1cccnc1 +O=S(=O)(Cc1ccccc1)Nc1cnn(Cc2ccccc2F)c1 +COc1ccc(S(=O)(=O)NCc2cn3c(C)cccc3n2)cc1 +Cc1cccc(NS(=O)(=O)c2ccc(F)cc2F)c1 +CCc1c(C(=O)Nc2cc(OC)ccn2)[nH]c(C)c1C(C)=O +Cc1ccc(CNC(=O)CC2(O)CCCCC2)cc1 +CCOC(=O)c1cn[nH]c1S(=O)(=O)NCC(F)(F)F +CCC(=O)N1CCc2c([nH]c3ccccc23)C12C(=O)Nc1ccccc12 +Cc1c(C(=O)N2CCN(C(=O)CO)CC2)sc2cccc(F)c12 +Cc1nc(=O)[nH]c(C)c1CCc1nc(C(C)C)nn1-c1ccccn1 +Cc1occc(=O)c1OCC(=O)N1CCc2ccccc2C1 +O=S(=O)(NCC1(O)CCCC1)c1cccc(C(F)(F)F)c1 +N#Cc1ccc(Oc2cccc(C(=O)N3CCCS3(=O)=O)c2)cc1 +COCCc1ncc(C(=O)Nc2cc(C)on2)c(N)n1 +COC(=O)C(c1cccnc1)N1CC=C(c2ccccc2Cl)CC1 +Cn1cc(Br)cc1C(=O)Nc1nc2ccccc2[nH]1 +O=C(OCc1nnc(-c2ccccc2)o1)C1CCCCC1 +Nc1nc(SCc2csc(-c3ccsc3)n2)n[nH]1 +CCOc1ncccc1NC(=O)c1ccc(F)c(F)c1 +N#Cc1ccc(C(=O)N2CCCC(C(=O)N3CCOCC3)C2)cc1 +CC(C)CCN(C(=O)c1ccc2ccccc2n1)C1CC1 +COc1cccc(C(O)CCC(=O)N2CCOCC2)c1 +Cc1cc(C(=O)N2CCCCC2C(=O)NCC(C)C)c(C)o1 +CCOC(=O)c1nnnn1Cc1ncc(C(F)(F)F)cc1Cl +Cc1ccc(C(O)CCCC(=O)N2CCN(C)CC2)cc1C +CC(=O)OCc1c(Br)cccc1C#N +Cn1cc(SCC(=O)N2CCCCCC2)c2ccccc21 +O=C(CSc1nnc(C2CC2)n1C1CC1)NC1CCCCC1 +O=C(Nc1cccc(C(=O)N2CCCCC2)c1)N1CCCC(O)C1 +C=CCNC(=O)Nc1ccc(C(=O)NCCC)c(Cl)c1 +CCOc1c(Cl)cc(C(=O)NCC(F)(F)F)cc1OC +CC(C(=O)NC(C)(C)c1ccccc1)n1ccnc1 +CC(O)CNS(=O)(=O)c1ccccc1Br +Cc1cnc(-c2nc(-c3ccc(N)cc3)no2)cn1 +O=C(NCCCn1ccnc1)c1cc(=O)c2ccccc2o1 +CC(c1cc2ccccc2o1)N(C)C(=O)NC1CCC(O)CC1 +CCc1c(-c2ccncc2)n[nH]c1NC(=O)c1cccc(OC)c1F +Cc1cc(NC(=O)c2cn(-c3cc(N(C)C)ncn3)cn2)ccc1F +Cc1ccc(CC(=O)Nc2ccccc2C(=O)N2CCOCC2)cn1 +CCCCS(=O)(=O)NCC(=O)c1ccc(Cl)cc1 +CCN(C(=O)c1cnc(OC(C)C)c(Cl)c1)C1CC1 +Cc1ccc(-c2noc(CN(C)CCN3CCOCC3)n2)cc1F +COc1ccc2c(c1)c(C(=O)CNc1nc(C)cs1)c(C)n2C +C#CCN1CCC(C(=O)NCC(C)Cc2ccc(OC)cc2)CC1 +CCCCNC(=O)CC(C#N)c1ccc(OC)cc1 +O=C(Cc1ccc(-n2cnnn2)cc1)N1CCOCC1C1CC1 +Cc1cc(C(N)=O)c(NC(=O)Cc2ccc(F)cc2F)s1 +OCc1cnnn1CCOc1cccc2ccccc12 +c1cnc(OC2CCCC2)c(CNCc2ccc(-n3cncn3)cc2)c1 +C#Cc1cccc(NC(=O)c2ccc3ncccc3c2)c1 +CC(=O)Nc1cc(C(F)(F)F)ccc1N1CCOCC1 +Nc1c(C(=O)Nc2cccc(Cl)c2)sc2ncccc12 +Cc1ccc(NS(=O)(=O)c2c(C)cc(C)cc2C)nc1 +O=C(c1ccc(O)cc1)N1CCN(Cc2noc(C3CC3)n2)CC1 +O=C(NCc1ccc(Cl)cc1)c1coc(NC(=O)C2CC2)n1 +COCCN1CCN(C(=O)NCc2oc3ccccc3c2C)CC1=O +CCOC(=O)c1nnn(Cc2cccc(C)c2)c1N +Cc1cc(NC(=O)CN(C)C(=O)CNC(=O)C(C)(C)C)no1 +c1cncc(COCc2nnc3n2CCN(C2CCOCC2)C3)c1 +CNS(=O)(=O)c1ccc(C(=O)N2CCCCCC2)cc1 +O=C(NCC(F)(F)F)c1cc(-c2cccnc2)ccc1F +CC(Oc1cccc(Cl)c1)C(=O)N(C)CC(O)C1CC1 +CCOc1ccc(CN2CCN(c3nc(C)ns3)CC2)cc1OC +COc1ccc(CNC(=O)c2cc(S(N)(=O)=O)c(C)o2)cc1F +O=C1Nc2ccc(S(=O)(=O)NCc3ccco3)c3cccc1c23 +Brc1cnn(CCn2nnc(-c3cccs3)n2)c1 +CCc1noc(CN(C)Cc2cnc(-c3cccnc3)s2)n1 +O=C(NC1CC1c1cccc(Cl)c1)c1cc(F)cc2[nH]cnc12 +Cc1ccc(OCC(=O)NC2CCCCNC2=O)cc1 +CCC(=O)N(CC1CCCO1)c1nc2ccc(C)cc2s1 +CCCOc1ccc(CN2CCOC(C(N)=O)C2)cc1OC +CNC(=O)c1cccc(COc2nnc(-c3ccccc3)o2)c1 +OCc1csc(CCCOc2ccccc2Cl)n1 +Cc1cnccc1CCNC(=O)NCc1sccc1C +CCc1ccc(S(=O)(=O)NC(C)C(=O)N2CCOCC2)cc1 +Cc1ccc(N2CC3CN(Cc4cccc(F)c4)C(=O)C3C2)nn1 +O=C(NCc1cc(-c2cccc(Cl)c2)no1)c1ccccn1 +Cn1c(N)nnc1SCC(=O)N(Cc1ccccc1)C1CC1 +CC(C)N(CC(N)=O)C(=O)Cc1c(F)cccc1F +CCc1ccc(NC(=O)CN(C)C(=O)c2c[nH]c3ccccc23)cc1 +CS(=O)(=O)N1CCCCC1C(=O)NCCCCN1CCOCC1 +Cc1ccc(NC(=O)Cn2cnc(C3CCC3)cc2=O)c(C)c1 +CSc1ccc(C)c(C(=O)N2CCC(C(N)=O)C2)c1 +CC1(C)OCC2(CO1)CN(C(=O)c1ccc(-n3cccc3)cc1)C2 +CCn1ccnc1C(O)c1ccc(OC)cc1OC +CN(c1ccccc1)c1cn2c(nc(=O)n2C(C)(C)C)s1 +CN(C)C(=O)c1nn(-c2ccc(Cl)cc2)c(=O)c2ccccc12 +Cc1c(CNc2ccc(F)c(N3CCCS3(=O)=O)c2)cnn1C +CSc1ncc(C(=O)NC(c2cccs2)C(C)C)cn1 +O=C1CN(C(=O)C2CN(C(=O)COc3ccccc3F)C2)CCN1 +CNC(=O)c1ccccc1C#CCNC(=O)Nc1ccccc1OC +CC(C)Cc1nnc(NC(=O)CSc2ccncc2)s1 +O=C(CCS(=O)(=O)c1ccc(O)cc1)Nc1ccccc1Cl +O=C(Nc1ccccc1C(=O)NCCc1ccccc1)c1ccco1 +Cc1oc(C(=O)OCC(F)(F)F)cc1S(=O)(=O)N1CCCC1 +O=C(Nc1nnc(Cc2ccccc2)o1)c1ccc(F)cc1F +CN(Cc1nc(-c2cccnc2)no1)Cc1cnc(C(C)(C)C)s1 +CC(=O)NCCCNC(=O)c1cc(-c2ccc(C)cc2)no1 +O=C(Nc1nc[nH]n1)c1ccc(C(F)(F)F)cn1 +CC(=O)c1cc(Br)ccc1OC(=O)c1ccco1 +Cc1noc(NC(=O)C(C)Oc2ccccc2Br)n1 +Cc1cc(C(=O)Nc2cccc(Oc3ccccc3)c2)no1 +CCCNC(=O)c1ccc(-c2cc(N3CCCCC3)ncn2)cc1 +O=C(CSc1nnc(-c2ccco2)o1)NC1CCCCCC1 +Cc1cc2ncn(CC(=O)Nc3cc(F)ccc3F)c2cc1C +Cc1cc(C(=O)COC(=O)c2ccc3ncsc3c2)c(C)n1C +CC(Sc1nncn1C)C(=O)Nc1ccc2ccccc2c1 +CCC(CC)C(=O)N1CCC(Oc2ccc(C)nn2)CC1 +COC(=O)C(C)(N)c1ccc(OC)c(C(C)C)c1 +O=C(NC1CC1)C1CCCN1C(=O)Cn1ncc(=O)c2ccccc21 +CSc1ccc(CC(=O)N2CCC(O)CC2)cc1 +Cc1cc2ncn(CC(O)c3ccccc3F)c2cc1C +C=CCNc1ncc(C(=O)NC(C)c2nc(C3CCCC3)no2)s1 +Cc1ccc(NC(=O)c2cnc3[nH]nc(C)c3c2)cc1S(C)(=O)=O +CCS(=O)(=O)NCC(C)(OC)c1ccccc1F +Cc1ccc(OCC(=O)OCC(=O)Nc2c(C)cc(C)cc2C)cc1 +CC1CCC(NC(=O)CCNS(C)(=O)=O)CC1 +COC(=O)C(CC(C)C)NC(=O)Cc1ccccc1Cl +COc1cc(C)c(S(=O)(=O)NC2CCCCNC2=O)c(C)c1 +CCOC1CCN(C(=O)NCc2nncn2CC)CC1 +CCN(C(=O)Cc1c(C)nc2cc(=O)[nH]n2c1C)c1cccnc1 +Cc1nnc(Cn2c(=O)c3ccccc3c3ccccc32)o1 +COc1ccc(C(=O)Nc2ccccc2OCc2cscn2)nn1 +Cn1nc(C(C)(C)C)cc1NC(=O)CSc1ncn[nH]1 +Cc1ccc(C)c(NC(=O)NC(C)c2cnn(C)c2)c1 +COc1ccc2nc(SCc3noc(-c4ccsc4)n3)[nH]c2c1 +Cc1ccoc1CN1CCN(C(=O)OCC(C)C)CC1 +COC(=O)c1ccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3)cc1 +CCN1CC2(CC1=O)CN(C(C)=O)CCN(C(=O)c1cccnc1)C2 +COC(=O)C1=C(N)Oc2cc(C)[nH]c(=O)c2C1c1ccc(Cl)cc1 +Cc1ccc(C)c(Cn2nccc2-c2ccncc2)c1 +CSc1cccc(NC(=O)N2CCN(C(C)=O)CC2)c1 +CCc1cc(=O)[nH]c(C2CCCN(C(=O)C3CC3)C2)n1 +COc1ccc(C(=O)NCC2CN(Cc3ccccc3)CCO2)nn1 +Cn1cc(C(=O)NCc2cnn3ccccc23)nn1 +COc1ncccc1C(Cc1ccsc1)NC(=O)c1ccnn1C +Cn1c(=O)oc2cc(NC(=O)NCc3ccc4ccccc4c3)ccc21 +COc1ccc(C(CC(=O)Nc2ccc(C)cc2C)NC(C)=O)cc1 +CC1CN(S(=O)(=O)c2c(N)cc(Cl)cc2Cl)CCO1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)N1CCOCC1 +CC1(C(=O)Nc2cc(C(C)(C)C)no2)Oc2ccccc2NC1=O +CCOc1nc(C)ccc1-c1noc(-c2ccccc2OC)n1 +CNC(=O)CN1CCN(C(=O)COc2ccccc2F)CC1 +C=CCn1cc(-c2cn(CCCN3CCCC3=O)nn2)c(C)n1 +CC(C)(CO)Nc1ncnc2onc(-c3ccc(F)cc3)c12 +CCCc1ccc(S(=O)(=O)N2CCN(CCC#N)CC2)cc1 +Cc1cccc(C(=O)N2CC(S(=O)(=O)c3ccc(Cl)cc3)C2)c1 +Cc1cccc2c(CC(=O)Nc3ccccc3SCCC#N)c[nH]c12 +O=C(Cn1cnc2ncccc2c1=O)Nc1ccc2c(c1)OCO2 +COC(=O)c1ccc(Cl)c(N2CCC(O)C2)c1 +COCCOc1ccc(NC(=O)c2ccc3c(c2)CCO3)cc1F +COC(=O)c1sccc1NC(=O)Cc1csc(-c2ccoc2)n1 +CN(C)c1ccc(C(=O)NCc2ccccc2N2CCCC2)cn1 +COc1cccc2c1OCC(O)C2N1CCOCC1 +CC(NC(=O)CCCn1cccn1)c1ccc(C(F)(F)F)cc1 +Cc1ccc2ncc(C(=O)OCc3ccc(-n4cccn4)cc3)n2c1 +COc1ccc(-n2c(SCC(N)=O)nnc2-c2ccco2)cc1 +O=C(NCC#CCOc1cccc(Br)c1)c1ccccn1 +CN(C)c1ncccc1C(=O)N1CCN(CC(C)(C)O)CC1 +CC(NC(=O)CSc1ncn[nH]1)C(=O)NCC(F)(F)F +CC(OCC(F)(F)F)C(=O)Nc1ccccc1Cl +CCn1cc(C#N)c(=O)n(CC(=O)NCc2cc(F)cc(F)c2)c1=O +CC(C(=O)NC1CCCN(c2ccccc2F)C1=O)C1CCOCC1 +CCOC(=O)C1CCCN1C(=O)c1ccc(N)cc1 +c1ccc(N2CCN(Cc3ccc(-n4ccnc4)cc3)CC2)cc1 +CC(Cc1ccccc1Cl)NC(=O)c1cccnc1 +O=C(Nc1cc(F)ccc1F)c1cccc(-n2cnnn2)c1 +Cc1nc(C)c(CCNC(=O)NCCc2nc(C)c(C)s2)s1 +CCOc1cccc(C(C#N)N(C)C(=O)c2cccc(F)c2)c1 +CN(C)c1cccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)c1 +CCN(CCn1cc(N)ccc1=O)CC(F)(F)F +Cn1cc(Br)cc(NC(=O)NCC2CCCO2)c1=O +CC(=O)c1csc(CCOc2cccc(Cl)c2)n1 +C#CCN1CCN(C(=O)CNc2ccccc2CC(F)(F)F)CC1 +CCN(CC)C(=O)c1ccccc1NC(=O)CNC(C)=O +COCC(=O)Nc1cc(S(C)(=O)=O)ccc1Cl +O=C(CC1C=CCC1)Nc1ccc(N2CCCC2=O)cc1 +Cc1nc(C)c(CCNC(=O)N2CCC(Cc3cnn(C)c3)C2)s1 +CSc1ccccc1NC(=O)N1CCn2c(nn(C)c2=O)C1 +COc1cccc(C(=O)NC(C)C(=O)NC(C)(C)C)c1F +CN1CCN(C(=O)c2ccnc(OC3CCC3)c2)C(C)(C)C1=O +CCOC(=O)N(C)c1ccc(NC(=O)C2CCCC2)cc1 +O=C(Cn1cnnn1)N1CCN(c2ccccc2F)CC1 +COc1cccc(NC(=O)CCC(=O)N=c2[nH]nc3ccccn23)c1 +COc1cc(CNC(=O)Nc2cc(C)on2)ccc1O +c1ccc(-c2nnc(CN3CCCSc4ccccc43)o2)cc1 +COc1ccc(CNc2ncnc3sc(C)c(C)c23)cc1 +NS(=O)(=O)c1ccc(C(=O)N2CCC(Cc3ccccc3)CC2)o1 +Nc1ccc2c(c1)N(CCCOc1ccccc1)CCCO2 +CC(=O)NC1CCN(c2cc(C)nc(-c3ccccc3)n2)C1 +NC(=O)NCCC(=O)N1CCN(Cc2cccnc2)CC1 +Nc1cc2c(cc1Oc1ccc(F)cc1)OCCO2 +Cc1ccc(NC(=O)CCc2ccc3nc[nH]c3c2)cc1 +CCc1nn(C)cc1CN1CCN(C(C)C(=O)N2CCOCC2)CC1 +CNC(=O)COc1ccccc1CNc1ccc(C)c(Cl)c1 +Cc1cc(C)c(NC(=O)Cn2cnc3cc(C)c(C)cc32)c(C)c1 +N#Cc1cccc(OCc2nc3ccccc3s2)c1 +O=C(Nc1ncnc2c1CCC2)c1ccccc1Br +CC(=O)NCc1nc2ccccc2n1CC(=O)N1CCCC1 +Cc1nc(CN)nc(-c2c(C)n(C)c3ccccc23)n1 +CN(CC1CCCCC1)C(=O)Cn1ccc(C(F)(F)F)n1 +CCCn1c(C)nnc1SCc1cc(=O)oc2c(C)c(O)ccc12 +CCCn1c(SCC(=O)NCC2CCCCC2)n[nH]c1=O +COc1cc(NC(=O)c2cc(C)on2)ccc1N1CCCC1=O +Cc1cc(COc2cc(Cl)ccc2C(N)=O)no1 +CN(CC(=O)NCC1CCC(C)(C)CC1)C(=O)c1ccccc1 +Cc1ccc(C(C)C)c(OC(C)C(=O)NCc2csc(C)n2)c1 +NC(=O)C1CCCN1C(=O)c1ccc(OCC2CCCCC2)cc1 +CC(NC(=O)NCc1ncn(C)n1)c1ccc2c(c1)OCO2 +CN1CCC2(CCC1=O)CN(C(=O)Cn1cccnc1=O)CCN2C +CCS(=O)(=O)N1CCC(C(=O)NCC(F)(F)F)CC1 +CCC(C)(C)NC(=O)CNc1cccc(OCC#N)c1 +O=C(CCNC(=O)c1cnc2snnc2c1)NCc1ccco1 +CC(NC(=O)CC(C)(C)C)c1ccc(-n2cncn2)cc1 +Cc1ocnc1CNC(=O)CN(C)C(=O)c1cccs1 +CC(CC1CCCC1)C(=O)N1CCN(C(=O)c2c[nH]c(=O)[nH]2)CC1 +COC(=O)CCNC(=O)COc1ccccc1Cl +CC(C)(CNC(=O)N1CCC2(CCC2)C1)c1ccncc1 +Cc1cc(CNC(=O)c2nnn(-c3cccc4cccnc34)c2C)on1 +COc1ccc(C(=O)N2CCN(CCO)CC2)cc1 +Cc1ccc(C(=O)N2CCCC(C(=O)Nc3ccccc3)C2)c(O)c1 +COc1ccccc1CN(C)C(=O)Cn1cc(-c2ccccc2)cn1 +O=C(NCc1ccc(F)cc1)N1CCCC(CO)(CC2CC2)C1 +CCCn1c(N)c(NCC2CCCCC2)c(=O)[nH]c1=O +CC(=O)Nc1ccc(OC(=O)Cc2ccc(Br)cc2)cc1 +N#CCC(=O)NCc1cc(F)ccc1Br +CC(C)CC(CNc1c(C#N)c(=O)n(C)c(=O)n1C)N1CCOCC1 +CCNC(=O)C1CN(C(=O)Nc2cccc3ccccc23)C1 +Cn1ccc(C(=O)NCCNc2nnnn2-c2ccccc2)cc1=O +Cc1cc(F)c(F)c(C(=O)N2CCOCC2)c1Cl +Cc1cccc(C(=O)Nc2ccc(N(C)C)cn2)c1 +Cc1nn(C)c(C)c1CCC(=O)Nc1nc2c(s1)CCC2 +Cc1nn(C)c(C)c1CN(C)C(=O)C(C)Cn1cc(Cl)cn1 +CC(O)CN(C)S(=O)(=O)Cc1cc(Cl)ccc1F +Cc1cc(C)nc(C(C#N)C(=O)CCCNC(=O)c2ccco2)n1 +O=C(CCOCC(F)(F)F)Nc1cccc2c1OCCO2 +Cc1nc(NC(=O)N2CCCC(O)C2)nn1C(C)C +COC(=O)c1cc(CNC(=O)NCC#Cc2ccccc2)oc1C +CCS(=O)(=O)N1CCCC(C(=O)NCc2cccs2)C1 +Cc1ccc(C(C)NC(=O)NCc2noc(C(C)(C)C)n2)cc1F +Cc1nn(C)c2ncc(NC(=O)NCC3CCCO3)cc12 +CCCNC(=O)C1CCCCC1C(=O)NCCc1ccc(O)cc1 +CCOc1ccc(F)c(C(=O)N(C)C(C)c2cccnc2)c1F +CCC(NC(=O)C(C)(C)C)c1ccc(OC)c(OC)c1 +CCN(CC(F)(F)F)C(=O)C(N)c1ccccc1 +Cc1ccc(F)cc1NC(=O)Cc1nc(C)c(C(=O)NC2CC2)s1 +CC(C(=O)NC(c1nnc2ccccn12)C(C)C)c1ccsc1 +N#Cc1cc2c(=O)n(Cc3cc(-c4ccccc4)[nH]n3)ccc2[nH]c1=O +Cc1noc(C)c1CNc1cccc(S(=O)(=O)C2CCCC2)c1 +CN(C)C(=O)Cc1ccc(NC(=O)Cc2ccc3ccccc3c2)cc1 +COC(=O)NCCC(=O)NC(C#N)c1ccc(Cl)c(Cl)c1 +COc1ccc(C(=O)Nc2ncccc2Cl)cc1 +Cc1cc(C)n(CC2CCCN2Cc2nc3ccccc3c(=O)[nH]2)n1 +O=C(NCc1ccc2c(c1)OCCO2)c1cc(C2CC2)[nH]n1 +CCc1sc(C(N)c2ccccc2OC)nc1C +O=S(=O)(Nc1nncs1)c1ccc2ccccc2c1 +Cc1nc2ccc(NC(=O)NCc3cccnc3)cc2o1 +CNC(=O)Cc1ccccc1NC(=O)c1ccc(C)s1 +CCC(C)NC(=O)c1ccc(NC(=O)c2ccc[nH]c2=O)cc1 +CC(CC1CCCC1)C(=O)NCC(=O)Nc1ccccc1 +OC(CN1CCOC(Cn2cccn2)C1)c1ccc2c(c1)OCCO2 +CC(=O)c1ccc(S(=O)(=O)Nc2ccn(C)n2)cc1 +O=C(NCCc1ccccn1)C1(c2ccc(Br)cc2)CC1 +CCOC(=O)CC(C)NC(=O)Nc1ncc(-c2ccccc2)s1 +C#Cc1cccc(N(C)C(=O)c2ncn(-c3ccccc3)n2)c1 +COC(C)(C)c1noc(C2=Cc3cc(Cl)ccc3OC2)n1 +CCC(=O)N1Cc2nn(-c3ccc(C)cc3C)c(-n3cccc3)c2C1 +COCc1cccc(NC(=O)Nc2ccccc2)c1 +Cc1nc(C)n(CC2CN(CC(=O)NCc3cccs3)CCO2)n1 +O=S(=O)(Cc1cccc(F)c1)c1ccc(Br)cc1 +C=CCn1c(=NC(=O)CC)sc2cc(NC(C)=O)ccc21 +O=C(NCCn1nc(-n2cncn2)ccc1=O)c1ccc(F)cc1F +CN(C)C(=O)C1CCN(C(=O)c2cc(Br)cn2C)CC1 +Cc1cccc(S(=O)(=O)C(C)C(=O)N2CCOCC2)c1 +CCCOc1nc(NCc2ccccn2)ccc1N +Cc1nnc(NCc2ccccc2OC(C)C)s1 +Cc1cc(C(=O)NC2CCCN(Cc3ccccc3)C2=O)c(C)o1 +NC(=O)c1nn(-c2ccc(F)c(F)c2)c2c1CNCC2 +C#CCNC(=O)CSc1nc(-c2cccs2)nc2ccccc12 +CCC1CCCCC1NC(=O)NC(C)c1nnc2ccccn12 +Cc1ccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3)c(C)c1 +O=C(CSc1nncs1)c1ccc(F)c(F)c1 +O=C(Nc1ccc2c(c1)OCO2)N1CC(c2nc(C3CC3)no2)C1 +Cc1noc(C)c1S(=O)(=O)N1CCc2cc3cccc(C)c3nc21 +C=CCNC(=O)CSc1nc2cc(Cl)ccc2s1 +C=CC(C)Sc1nc2sc3c(c2c(=O)n1C)CCC3 +Cc1cc2nc(C3CCCN(Cc4ccccc4)C3)cc(N)n2n1 +Cc1ccc(C)c(-c2cc(C(=O)OC(C)C)n(CCO)n2)c1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)C(=O)C(C)c1cccs1 +Cc1ccccc1CC(=O)Nc1cc(N)ccc1C +CCN(CCC#N)C(=O)CNc1ccc(Cl)c(C(F)(F)F)c1 +O=C(Cn1c(=O)oc2cc(Cl)ccc21)Nc1ccc(F)c(F)c1 +Cc1cncc(C(=O)OC2CCN(Cc3ccccc3C#N)CC2)c1 +CCOC(=O)c1nc(C(C)O)oc1C(F)(F)F +NC(=O)Cn1ccn2nc(-c3ccc4c(c3)OCO4)cc2c1=O +COCC(C)NC(=O)NCC1(c2ccc(F)cc2F)CC1 +NC(=O)c1cccc(NC(=O)C2(c3ccc(Cl)cc3)CCC2)c1 +Fc1ccc(Br)c(CSc2nncn2C2CC2)c1 +CC(C)(C)C(=O)CNC(=O)c1cc(Br)ccc1Cl +COCC(O)CN(C)C(=O)Nc1cc(-c2ccccc2)on1 +CCCCC(NC(N)=O)C(=O)Nc1cc(C)ccc1F +CCOc1ccccc1Nc1ncnc(NC)c1N +COCc1ccc(C(=O)OCc2nnc(-c3ccccc3)o2)cc1 +O=C(NC1CC1)C(Sc1ncccc1Cl)c1ccccc1 +Fc1ccc(-n2ncc3c(Oc4ccccc4)ncnc32)cc1 +COc1ccc(CC(CO)c2ccccc2F)cc1 +O=C(c1ccoc1)N(Cc1ccncc1)Cc1cccnc1 +CC(C)N(C(=O)CN(C)S(=O)(=O)c1ccc(C#N)cc1)C1CCC1 +O=C(c1ccc(O)cc1)C1CCN(C(=O)Cn2ccccc2=O)CC1 +CCCC(=O)OC1C(C2COC(C)(C)O2)OC2OC(C)(C)OC21 +Cc1ccccc1-c1nnn(CC(=O)NCc2ccccc2Cl)n1 +O=C(NCCCN1CCCC1=O)c1cnn2c1OCCC2 +COC(=O)C(C)Cc1ccc(NC(=O)NC(C)(C)C)cc1 +Cc1cccc(C(=O)N(C)CCNC(=O)C(C)C)c1O +CCn1c(CSc2ccccc2)nnc1SCC#N +Cc1ccc(S(=O)(=O)Nc2ccc(N)c(C)c2)s1 +CCCn1c(C)nnc1SCC(=O)Nc1ccnn1C1CCCC1 +Cc1cc(C)cc(C2(C(=O)N3CCC(C(N)=O)CC3)CCC2)c1 +Cn1cc(C(=O)Nc2cccc(C(N)=O)c2)c(C(F)(F)F)n1 +CN(C)S(=O)(=O)NCc1ccccc1N1CCOCC1 +CCOC(=O)CCS(=O)(=O)c1cccc(Br)c1 +C#CCCOc1ccc(CN2CCOC(C)C2C)cc1 +COCCn1c(N)nc2c(=O)n(C)c(=O)n(C)c21 +COc1ncccc1CNC(=O)Nc1ccc2ccccc2c1 +COc1cccc(OC)c1C(=O)Nc1ccc(C#N)c(Cl)c1 +NC(c1ccc(Cc2ccccc2)cc1)C(F)(F)F +Cc1cccc(C2NCCc3ccc(O)c(Cl)c32)n1 +COc1ccc(-c2ccc(C#N)c(NC3CC3)n2)c(OC)c1 +CCCc1nc2ncc(C(=O)N3CCOCC3)c(C)n2n1 +Cc1c(C(=O)OCC(=O)NCc2cccs2)oc2ccccc12 +CCCCCC(=O)N(C)c1ccc(S(C)(=O)=O)cc1 +COC(=O)C1(NC(=O)Cn2nc(C)ccc2=O)CCCCC1 +COC(=O)C(C)CNC(=O)c1ncn(-c2ccccc2)n1 +CCn1cc(C(=O)N2CCCC2c2ccc3c(c2)OCCO3)cn1 +COc1cc(C(=O)Nc2ccc(-c3nc(C)cc(=O)[nH]3)cc2)ccc1C +Cc1ccccc1S(=O)(=O)NCCc1c[nH]c2ncccc12 +COc1ccc(NC(=O)Nc2ncccc2C)c(OC)c1 +COc1cc(C(=O)Nc2nnc(C3CCCO3)o2)cc(OC)c1OC +Cc1cccnc1NC(=O)CNC(=O)c1cc(-c2ccccc2)on1 +O=C(NCc1ccc(Oc2ccccc2)nc1)NCc1cscn1 +CC(NC(=O)CCn1c(=O)oc2ccccc21)c1ccc(F)c(F)c1 +CCC(C)(C)NC(=O)c1ccc(NC(=O)N2CCOC(C)C2)cc1 +CC(Oc1ccccc1C(F)(F)F)C(=O)N1CCCn2ncnc21 +O=C(Nc1cc(N2CCCCC2)ncn1)C1CCC1 +CCN(c1ccc(OC)c(N)c1)S(=O)(=O)c1ccccc1 +CCn1c(COc2ccc(C)cc2)nnc1SCC#N +O=C(Cc1noc2ccccc12)NCCCn1cnc2ccccc21 +CN(C)c1nc2cc(NC(=O)c3ccc(=O)n(C)n3)ccc2o1 +CCC(C(=O)NC)N(c1cc(C)ccc1C)S(C)(=O)=O +CC(C)COc1cccc(C(=O)Nc2nccn(C)c2=O)c1 +COc1ccc(C2CCCN2c2ncnc3c2cnn3CCC#N)cc1 +COc1ccc(CN(C)Cc2cnc(-c3ccc(C)o3)s2)cc1O +Cc1n[nH]c(C)c1CCN(C)C(=O)Nc1ccc2c(c1)CCC2 +COc1ccc(COc2cc(C)c(N)cn2)cc1Cl +CCOC1(c2ccccc2)NC(=O)c2cc3c(cc21)OCCO3 +COc1cc(C)c(S(=O)(=O)NC(C)c2ccc(C)o2)cc1OC +CCC1c2ccsc2CCN1S(=O)(=O)CCCC(=O)OC +CCc1cc(C(=O)N2CCN(c3ccccc3)CC2)cs1 +Nc1oc(-c2ccccc2F)cc1C(=O)c1ccccn1 +Cc1ccc(-c2ccc(C(=O)N3CCCC(C)(CO)C3)s2)o1 +O=C1CCN(C(=O)c2ccccc2C(F)(F)F)CC1 +COc1ccc(-n2cnnc2SCC(=O)N2CCCCC2C)cc1 +Cc1cccc(C(=O)N2CCOCC2c2cccn2C)c1 +CC(OCC(F)(F)F)C(=O)Oc1ccc2c(c1)CCC(=O)N2 +CC1(C)CC1c1nnc(C(N)c2ccc(C#N)cc2)o1 +c1cc(CN2CCOCC23CCC3)cc(-c2ccncc2)c1 +COc1ccc(O)c(NC(=O)Cc2cccc(OCC#N)c2)c1 +CCOc1c(F)cccc1C(=O)OCc1noc(C)n1 +Cc1ocnc1C(=O)NCC(C)(C)c1ccncc1 +COc1cn(-c2ccccc2)nc1C(=O)NC(C)c1cccs1 +COc1ccc(CCN2C(=O)CCC2n2nc3ccccc3n2)cc1 +COc1ccc(NC(=O)Nc2ccc(-n3cnnn3)c(C)c2)cc1 +Oc1ccc2c(c1Cl)C(c1cc(Cl)ccn1)NCC2 +CN(C)C(=O)CN1CCN(C(=O)C2CC2c2cccc(Cl)c2)CC1 +COC(=O)c1ccc(OCC(=O)c2cnn(C)c2)cc1 +CC(C)S(=O)(=O)NCCc1ccc2c(c1)OCO2 +CCS(=O)(=O)N(C)CC(=O)Nc1c(C)cccc1Cl +COc1cccc(CS(=O)(=O)NCCc2nc(C)no2)c1 +Cc1csc(CCNC(=O)c2cccc(C)c2N)n1 +Cc1ccc(NC(=O)c2cccc(Oc3cnccn3)c2)cc1 +COc1ccc2c(c1)nc(-c1ccccc1)c(=O)n2CCCO +COc1ccccc1Nc1ncnc(Oc2ccccc2OC)c1N +Cn1ncc2c(N3CC=C(c4ccc(F)cc4)CC3)ncnc21 +CCC1COCCN1C(=O)CCC(=O)N1CCCCCC1 +CC(=O)N1CC(=O)N2Cc3ccccc3-n3cccc3C2C1 +CC(=O)C(NC(=O)CN1CCN(C(C)=O)CC1)C(C)C +Nc1cc(NC(=O)c2ccc(O)c(Cl)c2)ccc1Cl +O=S(=O)(c1ccccc1)N1CC2(CCN(c3ncccn3)C2)C1 +CC(C)CN1CCn2c(COCc3cccnc3)nnc2C1 +CCC(C)NC(=O)NCCn1c(-c2ccccc2)nc2cccnc21 +O=C(OCC(=O)N1CCCC1)c1ncn(-c2ccccc2)n1 +CN(Cc1cccc(Cl)c1)C(=O)CCc1cccnc1 +CCc1cc(=O)n2nc(C)c(-c3cccs3)c2[nH]1 +COCC(=O)N1CCN(Cc2ncccc2C)CC1 +CCNC(=O)NCC1(c2ccc(OC)cc2)CCOCC1 +CC(C(=O)NCCOC(N)=O)c1ccc2ccccc2c1 +CCOCCOC1CCCN(C(=O)Nc2ccc(C)cc2)C1 +CC1CCCN(S(=O)(=O)NCCNc2cnccn2)C1 +CC(=O)Nc1ccc(NC(=O)N(C)C(C)c2cccc(O)c2)cc1 +CCCn1nc(C(=O)N(C)Cc2ccc(C3CC3C)o2)ccc1=O +CC1CN(C(=O)C2CC(=O)N(Cc3ccccn3)C2)c2ccccc21 +CC(C)CC(=O)Nc1cccc(CNC(=O)Cc2ccc[nH]2)c1 +CN(CCOc1ccc(C#N)cc1)S(=O)(=O)c1ccc(F)cc1 +COc1cc(N)c2c(C(=O)NC3CCCCC3)nccc2c1OC +CC(=O)Nc1cc(NC(=O)Cc2c(F)cccc2F)ccc1Cl +CC(C)COc1cncc(NC2CCN(C(=O)c3ccco3)CC2)n1 +COC(=O)c1ccc(C(=O)OC)c(NC(=O)C2CC3CCC2C3)c1 +CC(C)(C)NS(=O)(=O)c1ccc(C(=O)Nc2cn[nH]c2)o1 +N#Cc1ccc(Cn2c(C#N)nc3cccnc32)cc1 +CCCCc1nc2cc(C(=O)NC3CCC3)ccc2o1 +COc1ccc(-c2noc(-c3sc4nc[nH]c(=O)c4c3C)n2)cc1 +CCNc1ncnc(Oc2cc(C)cc(C)c2)c1N +Cn1nc(C(=O)Nc2cccc(Cl)c2SC(F)F)ccc1=O +O=C(NCC1(O)CCCc2ccccc21)Nc1ccncc1 +O=C(c1ccc(Cl)cc1)N1CCN(C(=O)C2CCCO2)CC1 +CCn1nccc1CN(C)c1nc(N)nc2c1nc(C)n2C +COc1cc(OC)cc(C(=O)NCC2C(=O)N=C(C)C=C2C)c1 +COc1ccc(C(=O)COc2ccccc2C(N)=O)cc1 +CCC(CO)NC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +COC(=O)C(C)(C)NC(=O)c1ccc(OC)cc1Br +COc1cccc(NC(=O)COC(=O)c2ccc(OC)c(F)c2)c1 +O=C(NCCc1cccs1)N1CCN(c2nccs2)CC1 +COc1ccc(Cl)cc1-c1cc(NC(=O)C2CCOCC2)[nH]n1 +CC1(NC(=O)c2ccc(N3CCNC3=O)cc2)Cc2ccccc2C1 +Cc1cc(NC(=O)c2cnc(C3CCCO3)s2)ccn1 +CC(C#N)NS(=O)(=O)Cc1ccc(Cl)cc1 +Cc1cc(C)c(S(=O)(=O)NCCCCn2ccccc2=O)c(C)c1 +Cc1ccc(CNC(=O)C(NC(N)=O)C(C)C)cc1 +CCc1noc(CC)c1CC(=O)NCc1nncn1C1CC1 +COc1ccc(CC(C)C(=O)Nc2cccc(C(N)=O)n2)cc1 +O=C(CNc1ncccn1)NCCc1ccccc1 +CCc1noc(CC)c1CNC(=O)c1ccoc1C +CC(=O)NCCC(=O)Nc1ccc2c(c1)OC(C)(C)O2 +O=C(Nc1cc(-c2ccccc2Br)n[nH]1)c1cc[nH]n1 +CC1CC1C(=O)NC1CCN(c2ccc(F)cc2)CC1 +O=C(NCCCc1n[nH]c(=O)[nH]1)c1ccc(Cl)cn1 +CCN(CCOc1ccccc1C)C(=O)c1cn(CC)nc1C +CCCNC(=O)CN1c2ccccc2SC(C)C1C +CC(NS(=O)(=O)c1ccc(F)c(N)c1)C(=O)N(C)C +Cn1ccc(C(=O)N2CCC(C(O)Cc3ccccc3)CC2)cc1=O +COc1ccc(NC(=O)Nc2cnc(OC)nc2OC)c(C)c1 +CCN(CC)C(=O)C1CC=CCC1C(=O)n1cnc2ccccc21 +COc1ccc(F)cc1C(O)CCC(=O)N1CCCCC1 +COc1ccc(C(C)C(=O)NCC(C)(C)NS(C)(=O)=O)cc1 +Nc1c(C(=O)Nc2ccc(Cl)cc2)oc2ccccc12 +COCc1c(Br)cccc1NC(=O)C(C)n1cccn1 +CCCCCCC(C)NC(=O)c1cn2cccnc2n1 +COc1cc(F)c(S(=O)(=O)N2CCCCCC2)cc1OC +CC(C)NC(=O)c1cc2ccc(OC(=O)C(C)(C)C)cc2oc1=O +COCc1ccccc1NCc1nnnn1-c1ccccc1 +CCCNc1ncnc(Nc2ccc(F)cc2F)c1N +CCOCc1nnc(NC(=O)c2ccnc(OC)c2)s1 +CCCNC(=O)c1ccc(NC(=O)c2coc(-c3ccccc3)n2)cc1 +COc1ccccc1C(NC(=O)Cc1ccc(O)cc1)c1ccccn1 +COc1cc(=O)n(Cc2ccc(C(N)=O)cc2)cc1Br +CCOc1cc(C2CC(=O)Nc3c2cnn3C(C)C)ccc1O +CCC(C)Oc1ccc(NC(=O)C(C)OC)cc1 +c1csc(Cc2noc(CCn3cccn3)n2)c1 +CC(NC(=O)NC(C)C(=O)N1CCCCC1)C(=O)NC(C)(C)C +Cc1cc(C)cc(NC(=O)N2CCn3c(nn(C)c3=O)C2)c1 +CCOC(=O)c1ccn(-c2ccc(NC(=O)C3CC3)cc2)n1 +Cc1nn(C)cc1C(=O)N(C)Cc1c[nH]nc1-c1ccc(F)cc1 +NC(=O)C1CCN(C(=O)c2ccccc2Br)CC1 +CCCCN(CCO)C(=O)c1ccc(C)c(N)c1 +CC(CC(=O)Nc1ccc2nc[nH]c(=O)c2c1)C1CC1 +CCc1nc(COC(=O)c2ccc(N3CCCC3=O)cc2)cs1 +CC(OC(=O)c1cc(C(N)=O)cs1)c1ccc(Cl)cc1 +COc1ccccc1NC(=O)c1ccc(NCc2cc(C)on2)cc1 +CCn1c(SC(C)C(=O)Nc2ccc(C)cc2)nnc1C1CC1 +COCC(=O)N1CCOc2c(cc(-c3ccc(C)cc3)cc2OC)C1 +CC1(C(=O)N2CCCC2C(=O)Nc2cccc(-n3cccn3)c2)CC1 +Fc1cc(Br)c2c(c1)C(C1CC1)NCC2 +Oc1ccc2c3c(ccc2c1)CCNC3Cc1cccnc1 +CC(=O)Nc1ccc(NC(=O)CCc2ccc3ccn(C)c3c2)cc1 +CC(CCCO)NC(=O)Nc1cccc(N2CCCC2=O)c1 +CC(=O)Nn1ccc2c(cnc3nc(-c4cccnc4)nn32)c1=O +COC(=O)C(C)CN(C)C(=O)c1scnc1C +CCc1nn(C)cc1C(=O)Oc1cc2cnccc2cc1OC +O=C(CCC(=O)N1CCc2sccc2C1)NCCc1ccco1 +CCCNC(=O)C1CCN(S(=O)(=O)c2ccccc2F)CC1 +CCCNC(=O)CNC(=O)Nc1nc2ccccc2s1 +CN(CC(O)C1CC1)C(=O)Nc1cc(F)cc(Br)c1 +CNc1ccc(C(=O)NC(C)C)cc1C(F)(F)F +COc1ccc(F)cc1NC(=O)Cc1nc(-c2ccsc2)oc1C +Brc1csc2snc(-c3cc[nH]c3)c12 +COc1ccc(C(=O)Nc2cc(C(C)(C)C)n[nH]2)cc1OC +Cc1cc(C)cc(OCc2ccc(C(=O)NC3CCOC3=O)o2)c1 +CC(C)NS(=O)(=O)c1ccc(NCc2nnc(C3CC3)o2)cc1 +O=C(c1cc2cc(F)ccc2[nH]1)N1CC(O)C(N2CCOCC2)C1 +CC(C)(Br)C1NCCc2ccc3cc[nH]c3c21 +O=C(NCC12CC3CC(CC(C3)C1)C2)N1CCC(n2cncn2)CC1 +Cn1nc(CNc2ncccn2)c2c1CN(c1cnccn1)CC2 +Cc1noc(C)c1CC(=O)NCCc1cccc2ccccc12 +Nc1ccc(C(=O)NC2CCCCCC2)c(Cl)c1 +CCC1CN(Cc2nc(-c3cc(OC)ccc3OC)oc2C)CCO1 +CC(=O)Nc1cc(C(=O)Nc2cccnc2-n2cccn2)ccc1C +Cn1c(=O)ccn(CC(=O)Oc2ccc(C3CCCCC3)cc2)c1=O +O=S(=O)(Cc1ccc(F)cc1)NCCc1cn2ccccc2n1 +O=C(c1cn(-c2ccccc2Br)nn1)N1CCOCC1 +CN1CCN(S(=O)(=O)Cc2ccccc2F)CC1 +Cc1cc(NC(=O)CNc2ccc(F)cc2)n(C(C)(C)C)n1 +CCn1c(SCCCC#N)nnc1N1CCOCC1 +CCc1ccc(CN2C(=O)CNc3ccccc32)cc1 +CC(=O)N1CCN(CCC(=O)Nc2sc3c(c2C#N)CCC3)CC1 +O=C(Nc1cc2c(cc1Cl)OCCO2)C1CC1 +CC(C)(C)c1n[nH]cc1CNCCc1ccc(S(N)(=O)=O)cc1 +COc1ccc(C)cc1CCNc1cc(C)nc2ncnn12 +COc1ccccc1NC(=O)c1ccc(-n2nccc2C)cc1 +Cc1ccc(-n2nnc(CO)c2CC(C)C)c(C)c1 +CCN(CCO)c1nc(C)nc2sc(-c3ccccc3)cc12 +COc1cc(C2OCC3(CO2)CC2C=CC3C2)ccc1O +CCn1nc(C)c(CNC(=O)NCC2(c3ccccc3F)CC2)c1C +CCOC(C)c1nccn1Cc1cc(F)cc2cccnc12 +Cc1ccc(C(=O)Nc2ccc(C(F)(F)F)n(C)c2=O)cc1C +Cc1oc2ncnc(OCC(=O)Nc3ccc(Cl)cc3)c2c1C +CCc1ccc2oc3c(c(=O)c2c1)C(c1ccncc1)N(CC)C3=O +CN(C(=O)Nc1ccc(-c2nnnn2C2CC2)cc1)C1CCCCC1 +CCNC(=O)NC1(C(=O)NCc2c(C)cc(C)cc2C)CCCC1 +CCCNc1nc(SC)nc2c1cnn2CCNC(C)=O +CC(=O)c1ccc(OCC(=O)C(C#N)c2nc(C)cc(C)n2)cc1 +Cc1cccc(NC(=O)CSc2nnc3[nH]c(=O)cc(C)n23)c1 +CCOC(=O)c1ncn(-c2cccc(C(C)C)c2)n1 +C=C(C)CN(C)C(=O)c1cc2n(n1)CCCN(C(C)=O)C2 +Cc1ccc(C(=O)Nc2cc(Cl)ccc2N)s1 +CN(C)C(=O)CN(C)C(=O)COc1ccc(Cl)cc1 +O=C(NCCc1nnc2n1CCC2)N1CC2CCCC2C1 +CCCn1cc(NC(C)c2ccccc2)ccc1=O +Cn1cnc(CNC(=O)Cc2cn(C)c3ccccc23)n1 +Cc1cccnc1CNC(=O)NC1CCN(C(=O)C2CCCCC2)C1 +COCCNc1ccccc1CNC(=O)Nc1cnccc1C +CC(C)(C)N1C(=O)CC(=O)CC1c1ccc(Cl)cc1 +O=C(COc1ccccc1)Nc1cc(-n2cncn2)ncn1 +CCN1CC(n2cc(COCc3ccccc3)nn2)CC1=O +CCc1cccc(CC)c1NC(=O)NCC(C(C)C)N1CCOCC1 +COc1ccc(C2(C(=O)NCc3ccnn3C)CCCCC2)cc1 +Cc1ccc(Oc2cccc(C(=O)NCCc3ccccc3)c2)nn1 +COc1ccc(C(=O)NCc2coc(-c3cccs3)n2)c(F)c1 +CC(O)(CNC(=O)NC1CCCCC1n1cccn1)c1ccco1 +Cc1nc(CNC(=O)CCCn2cncn2)c(C)s1 +CC(CC#N)N(C)C(=O)Nc1cccn(Cc2ccccc2)c1=O +CC(=O)N1CCC(NC(=O)NCc2ccc3c(c2)OCCCO3)CC1 +Cc1nc(N(C)Cc2nc3ccccc3s2)c2nc(C)oc2n1 +Cc1nc(C2CCCN2CCc2cnn(C)c2)no1 +CC1CC(N2CCN(C3=NS(=O)(=O)c4ccccc43)CC2)C(=O)O1 +CC(=O)N1CCN(Cc2cnc3ccc(N)cn23)CC1 +O=C(OCc1cccc(F)c1)c1ccc(-n2ccnn2)cc1 +CC(C)N1CCOC(Cn2cc(Br)cn2)C1 +COC(=O)c1ccc2ccn(CCC(=O)N3CCCC3)c(=O)c2c1 +CC(C)C(C#N)NS(=O)(=O)c1ccc2c(c1)CCCC2 +CCc1ccc2nc(NCCN3CCOCC3)sc2c1 +Cc1cc2c(cc1C)OC(C(=O)NCc1ccon1)C2 +Cn1cc(NC(=O)C2CCCN(C(=O)c3ccoc3)C2)cn1 +O=C(NCCc1c[nH]c2ccccc12)Nc1ccc2c(c1)OCCO2 +Cc1noc2nc(C(C)C)cc(C(=O)NC3CCCc4occc43)c12 +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)OCO3)cc1C(N)=O +O=C(NCc1ccccc1OC(F)F)c1ccccc1-n1cnnn1 +CCC(=O)N1CCCCC1C(=O)Nc1ccc(C(N)=O)cc1 +CN(Cc1nc2ccccc2[nH]1)S(=O)(=O)CCC(C)(C)C +COC(=O)C1CC(Oc2ccc3c(c2)CCC3)CN1 +O=c1[nH]cccc1NCc1ncc(-c2ccccc2)o1 +CCc1noc(C(C)S(=O)c2cc(OC)c(OC)cc2C)n1 +Oc1ccc(C2NCCc3ccc(O)c(F)c32)c(Cl)c1 +CCC(C)(C)NC(=O)C1CCN(S(=O)(=O)CC)CC1 +CN(C)C(=O)C1CCCN(C(=O)Nc2ccc(C(F)(F)F)cc2)C1 +N#Cc1ccc(-c2c(F)ccc(F)c2F)[nH]c1=O +CCCCNC(=O)C1CCCN(C(=O)C(C)NC(=O)c2ccco2)C1 +CCOc1ccccc1C(=O)NCc1c(C)nc2sc(CC)nn12 +CC(C)(C)NC(=O)COC(=O)C12CC3CC(CC(C3)C1)C2 +CC(C)NC(=O)COC(=O)c1cccc(N2CCCC2=O)c1 +CNS(=O)(=O)c1ccc(N2CCCCCC2)c(N)c1 +Cc1cccc2nc(CSc3nncs3)cc(=O)n12 +O=C(NC1CC1)c1ccc(=O)n(Cc2cccc(F)c2)n1 +COc1ccccc1-c1nc2sc3c(n2n1)CCNC3 +Cc1c(S(=O)(=O)Nc2cnn(CCc3ccccc3)c2)cnn1C +CCN(Cc1ccco1)C(=O)NC1CCN(c2ncccn2)CC1 +COCCOC1COCCN(S(=O)(=O)c2ccc(F)cc2)C1 +COc1cccc(OCC(=O)Nc2cccc(C(C)=O)c2)c1 +COc1ccc(NC(=O)CN2CCN(c3ccc(C)cc3)C2=O)cn1 +Cn1c(C(F)(F)F)nn(CCNC(=O)c2cccs2)c1=O +CC(=O)Nc1ccc(NC(=O)CNc2ccccc2C)cc1 +Cc1cccc(C)c1NC(=O)NCCc1nc2ccccc2s1 +CN(CC(=O)Nc1ccc(OC(F)(F)F)cc1)C(=O)C1CCC1 +COc1cc(C)c(C(C)C)cc1S(=O)(=O)N(C)C +CSc1ncnc(NCCn2cc(Cl)cn2)c1C#N +Cc1noc(C)c1N(C)C(=O)NC(C)COCC(C)C +COCC1CN(C(=O)Cc2ccccn2)Cc2c1cnn2C +COc1ccc(C=Cc2nnc3c(N)cc(Cl)cn23)cc1OC +Nc1nccnc1C(=O)Nc1nnc(-c2cccc(Cl)c2)s1 +O=C(NCc1ccc(OCc2ccccc2)cc1)c1ccc[nH]1 +CC1CCC(NC(=O)c2ccc(N(C)C)cc2)CC1 +CNC(=O)c1cccc(C(=O)N2Cc3ccccc3N(C)CC2C)c1 +COc1ccc(S(=O)(=O)N(C)Cc2cccc(C#N)c2)cc1OC +CCC(=O)N1CCCC(Cn2cc(-c3ccc(F)cc3)nn2)C1 +COc1cc(OC)cc(C(=O)Nc2nnc(-c3cc(C)nn3C)o2)c1 +CCCOCC(=O)Nc1cccc(C(N)=O)c1C +Cc1snnc1C(=O)Nc1cccc2c1CCCC2 +Cc1nc(CN(C)C(=O)C2CCC(=O)N2)cs1 +Cc1sc(NC(=O)c2ccc(S(C)(=O)=O)cc2)c(C#N)c1C +CCC(C)c1ccc(NC(=O)c2cn(C)nc2C)cc1 +CCc1cccc(OCCCCN2CCOCC2)c1 +Cc1cc2c(cc1C)N(CC(=O)N1CCCC1)CCN2 +CCc1nc(NCCc2nc(C)c(C)s2)c2cnn(C)c2n1 +O=C(Cn1nc(-c2ccccc2F)ccc1=O)c1ccccc1 +O=C(Oc1cccc(N2CCCC2=O)c1)c1cccc2ncccc12 +CCCCOc1cccc(NC(=O)NCc2nncn2C)c1 +NC(=O)c1cnc(NCC2COc3ccccc3O2)c(Cl)c1 +O=C(Cc1cccs1)N1CCOCC(CO)C1 +O=c1[nH]nc(CN2CCC(OCC3CCCO3)CC2)[nH]1 +CCNS(=O)(=O)c1cccc(C(=O)NCc2ccccn2)c1 +CCOC(=O)c1[nH]c(C)c(C(=O)C(C)N(C)C(C)=O)c1C +Cn1c(N)c(CN2CCN(c3cccc(Cl)c3)CC2)c(=O)[nH]c1=O +O=C(COc1nnc2ccccn12)Nc1ccc(Cl)c(Cl)c1 +CCNC(=O)C(C)NS(=O)(=O)c1cc(C)cc(N)c1 +O=C(NCc1ccccc1F)c1cn2c(n1)COCC2 +C#CCOc1ccc(CNc2cccc(-c3nc[nH]n3)c2)cc1 +Cc1cc(F)ccc1CCNC(=O)CNC(=O)c1cccc(F)c1 +COCc1oc(C)c(C)c1-c1csc(NC(C)C)n1 +CN1CCOC(C(=O)N(Cc2cccnc2)Cc2ccco2)C1 +N#CC(C(=O)Cc1cc2ccccc2[nH]c1=O)c1nc2ccccc2[nH]1 +CCOc1ccccc1NC(=O)Cc1cccc(N)c1 +CCC(C)C(=O)CSc1nnnn1-c1ccc(C)cc1 +COC(CNS(=O)(=O)N(C)C1CCCCC1)c1ccccc1 +O=C(Nc1cc(-c2ccccn2)no1)c1ccccc1Cl +OC(CNCc1ccco1)c1c(F)cccc1Cl +CNS(=O)(=O)c1ccc(Oc2ccccc2N)cc1 +COc1ccc(CCNC(=O)NCc2cc(F)ccc2F)cc1 +CC(C)(C)Cc1nnc(NC(=O)Cc2ccc(F)cc2)s1 +Cc1nc(NCc2ccccc2)c2ccsc2n1 +Cc1noc(CNc2ccccc2CN2CC(C)OC(C)C2)n1 +CCOc1ncccc1C(=O)Nc1ccc(OC(F)F)c(F)c1 +CCC(C)NC(=O)C1CCCN(c2cnc3nccnc3c2)C1 +CC(=O)NC1CCCN(C(=O)Nc2ccc(Cn3cccn3)cc2)C1 +Cc1oc(-c2ccccc2)nc1C(=O)N(C)Cc1nc2ccccc2[nH]1 +Cc1ccc(C)c(C(=O)CCC(=O)N(C)c2ccccc2)c1 +CC(C)Cc1ccc(CNC2CCN(C(C)C)C2=O)cc1 +CCOc1ccc(Br)cc1NC(=O)CCCOC +O=C(Nc1ccc2c(c1)OCCCO2)c1cc(=O)c2ccccc2o1 +N#CCSc1nc2ccccc2c(=O)n1-c1ccc(F)cc1F +O=C(NCc1nc2ccccc2s1)Nc1cccc(F)c1F +COc1ccccc1C(NC(=O)N(C)C(C)C)c1nccn1C +CN(C1CCCCC1)S(=O)(=O)N1CCN(Cc2cc[nH]n2)CC1 +CN(C)C(=O)c1ccc(Cl)cc1NCC(=O)NC1CC1 +Cc1cc(Br)cc(C)c1NCC(=O)N1CCCC1 +CCOC(=O)CNC(=O)c1ccccc1OCC +Cc1cnc(C(=O)N(C)c2ccc(C(N)=O)cc2)cn1 +CCOc1ccc2cc(C(=O)NCc3cscn3)[nH]c2c1 +Cc1nc(C(=O)OC2(C3CC3)CC2)nn1-c1ccc(F)cc1 +Cc1ccc(CN(C)C(=O)CCC2CCCO2)o1 +Cc1nn(C(F)F)c(C)c1CC(=O)Nc1cc[nH]n1 +COC(=O)c1c(C(=O)OC)c(C)n(Cc2ccco2)c1C +C=C(C)CN(CC)C(=O)c1cc(S(=O)(=O)N(C)C)ccc1Cl +COC(=O)N(C)c1ccc(NC(=O)NCc2ccc(C)s2)cc1 +Cc1cccc2sc(NC(=O)c3cc(C)n(C(C)C)n3)nc12 +Cc1ccc(C(=O)Nc2ccc(NC(=O)c3ccccc3)nc2)c(C)n1 +CC1CCN(CCN2CCCC2=O)c2ccccc21 +CC(C)CC(=O)N(c1ccc(O)cc1)S(=O)(=O)c1ccccc1 +CC1CCCN(C(=O)CNc2ccc(F)cc2OCC2CC2)C1 +Cn1cc(C(=O)N2CCC3(CC(Oc4cccnc4)CO3)C2)cn1 +O=C(NC1CCCCC1)c1ccc(-c2cccnc2)nc1 +CCCN1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 +CCOc1ccc(CN(C)C(=O)CCc2c(C)[nH]c(=O)[nH]c2=O)cc1 +COc1ccc(OC)c(-c2cc(Cl)c(C#N)cn2)c1 +CC(NC(=O)Cc1cccc(F)c1)c1cccs1 +CCCNC(=O)c1cc(Br)ccc1Cl +Cc1cc(C(=O)NCc2nc3ccccc3[nH]2)c(C)n1C1CC1 +CCc1nc(CC(=O)NCc2nnc3ccccn23)cs1 +O=C1CCC(COC(=O)CSc2cc(Cl)ccc2Cl)N1 +Cc1ccnc(C2CCCCN2C(=O)C2CCC2)n1 +CCC(C)NC(=O)CNc1ccc(Br)cc1 +CCCC(C)(C)NC(=O)c1ccc(-c2n[nH]c(C)n2)cc1 +CC(C)NC(=O)CCNC(=O)c1scnc1C1CC1 +NC(=O)c1cnc(NC(=O)C2CC(=O)N(Cc3ccccc3)C2)s1 +CC1CCC(N(C)C(=O)CSc2nnnn2C)CC1 +O=C(CNc1ccc(Br)cc1F)NC1CCOCC1 +COc1c(CNC(=O)c2ccc(O)cc2F)c(C)nn1C +Cc1nc(C(=O)NCCc2c[nH]c3ccccc23)cs1 +Cc1ccc(S(=O)(=O)n2c(=O)oc3ccccc32)cc1 +CCc1onc(C)c1NC(=O)C1CC(=O)N(Cc2ccccn2)C1 +CC(=O)c1cccc(NC(=O)C(C)Sc2nc(C)cs2)c1 +CC(C)c1csc(C(C#N)C(=O)c2ncn(-c3ccccc3)n2)n1 +CC(C)CC(C(=O)NCc1ncn(C)n1)N1CCCCC1=O +CC(C)c1nnc2n1CC(CNc1ccc(C#N)cn1)CC2 +Cc1ccccc1-n1c(C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 +Cc1ccc(C(C)NC(=O)Nc2cccc(C#N)c2)s1 +O=C(c1cccc(F)c1)N1CCC(c2ccncc2)CC1 +Cc1ccc(OCC#CCNC(=O)c2cc(=O)c3ccccc3o2)cn1 +CCc1ccc(C(=O)N(CC)CCC(F)(F)F)cc1 +CCNS(=O)(=O)c1ccc2c(c1)N(C(C)=O)CC(C)O2 +Cc1noc(C(C)OC(=O)c2csc(-c3ccc(C)o3)n2)n1 +O=C(Cn1ccccc1=O)NCCOCc1ccc(Cl)cc1 +CCOc1ncccc1NC(=O)c1cc(C(C)C)n(C(C)(C)C)n1 +CCCNC(=O)CSc1nnc(C(F)(F)F)n1C +CN(CC1CCCCO1)C(=O)c1nc(-c2ccccc2)oc1C1CC1 +CC(C)c1nnc(NC(=O)CNC(=O)c2ccsc2)s1 +CCc1nn2c(=O)cc(CN(CC)Cc3ccc(F)cc3)nc2s1 +Cc1cc(C)n(-c2ncnc(Sc3cccc4cccnc34)c2N)n1 +COc1ncccc1CNC(=O)CCC(=O)Nc1nccs1 +CN1CCN(C(=O)C2(C#N)CCOCC2)CC12CCNC(=O)CC2 +Cc1csc(COC(=O)CCC(=O)c2ccc(F)c(F)c2)n1 +O=C(Cc1ccc2c(c1)CCC2)NCc1nc2ccccc2[nH]1 +Cc1ccc(CNC(=O)N2CCN(C(=O)c3ccoc3)CC2)c(C)c1 +OCCc1cnn(-c2cccc(-n3cnnc3)c2)c1 +CCN1CCSc2ccc(C(=O)NCCCOC)cc21 +Cc1ccc(OCCNC(=O)NCC(C)C)c(C)c1 +Cc1nsc(N2CCN(Cc3occc3C)CC2)n1 +O=C(CSc1ccccc1F)N1CCCS1(=O)=O +COc1ccc(S(=O)(=O)N2CCC(C#N)CC2)cc1 +COc1ccccc1-c1ocnc1C(=O)NC(C)CCc1ccco1 +CCC(C(=O)Nc1ccc(C(=O)N(C)C)cc1)c1ccccc1 +CCC(CC)C(=O)NCC(=O)c1cc(Cl)ccc1OC +CCNC(=O)c1ccc(NC(=O)NC(C)c2ncnn2CC)c(C)c1 +CCN(CC1CCOC1)C(=O)NC1CCN(S(C)(=O)=O)CC1 +CCOC(=O)c1cnn(CC(F)(F)F)c1-c1ccccc1OC +CC(NC(=O)NCCC(N)=O)c1ccc2c(c1)CCCC2 +NC(=O)COC(=O)CSc1cccc(C(F)(F)F)c1 +C#CCNS(=O)(=O)c1ccc(C(=O)Nc2cc(C)n[nH]2)cc1 +COc1ccc(-n2ncc3c(N4CC(C)CC(C)C4)ncnc32)cc1 +Cn1ncc(Cl)c1C1CCCCCN1C(=O)c1ccco1 +N#Cc1c(N)nc2c(c1-c1cccc(O)c1)CCc1[nH]ccc1-2 +CCCn1c(C)nnc1SC(C)C(=O)Nc1ccc(F)c(F)c1 +Cc1cccc2c(=O)n(CCC(=O)N3CCOC(C)C3)cnc12 +CCOc1cc(CNC(=O)NCc2ccc(F)c(C)c2)ccn1 +CC1CN(Cc2cc(=O)oc3cc4c(cc23)CCCC4)CC(C)O1 +CCC(C)C(=O)Nc1nc2c(OC)cc(N)cc2s1 +Cc1cc(C(=O)Nc2[nH]ncc2-c2ccccc2Br)no1 +COCC(=O)N1CC2CN(c3cccnc3)C(=O)C2C1 +CN(C)C(=O)c1cccc(CCNC(=O)c2scnc2C2CC2)c1 +COCc1ccccc1C(=O)N1CCN(C2CCCC2O)CC1 +CC(C)CC(NC(=O)Cn1cc(Cl)cn1)c1ccccc1 +C=Cc1cc(OC)c(OCc2nc(C)cs2)c(OC)c1 +COC(=O)c1c(NC(=O)c2ccccc2)csc1C +COc1ccc(-n2c(N)c(C#N)c(-c3ccccc3)c(C#N)c2=O)cc1 +COc1ccccc1NC(=O)COC(=O)c1ccc(C)c(F)c1 +CCC(C)NC(=O)c1ccc2c(=O)n(C3CCCC3)c(=O)[nH]c2c1 +O=S(=O)(CCc1ccccc1)N1CCOC2CCCCC21 +CCN(CC)C(=O)c1c[nH]nc1-c1cccc(Cl)c1 +Cc1ccccc1C(CC(=O)Nc1ccc(Cl)c(F)c1)NC(N)=O +CS(=O)(=O)N1CCC(c2nccnc2N2CCC(O)C2)CC1 +Clc1cccc(C2(CNCc3cscn3)CCOCC2)c1 +Cc1cccn2c(=O)c(C(=O)NC3CCCC3)cnc12 +CCc1cc(NC(=O)NCCNC(=O)N(C)C)ccc1C +CN(CCc1ccc(F)cc1)C(=O)Cn1ccc(=O)[nH]c1=O +Cc1cc(C)c(CNC(=O)NC(C)c2ccccn2)c(=O)[nH]1 +COc1cc(C(=O)N2CCN(C(=O)C3CC3)CC2)ccc1C +O=C(NC1CC(=O)N(C2Cc3ccccc3C2)C1)c1cccnc1 +CC(=O)Nc1ccc(SC(C)C(=O)N2CCCC2)cc1 +CCCN(CC(=O)NC)S(=O)(=O)c1cccc(Cl)c1F +CSc1ccsc1C(=O)N1CCN(C(=O)CCC(C)C)CC1 +CCCCNC(=O)c1cc(=O)oc2cc(OC(C)C)ccc12 +Cc1ccc(C)c(OS(=O)(=O)c2cccc(C#N)c2)c1 +CCn1cc(Cl)c(C(=O)Nc2ccc(Cl)cc2F)n1 +CCn1nc(C)cc1C(=O)NCc1c(C)nn(CC)c1C +COc1ccc(SCc2csc(-c3ncccn3)n2)cc1 +Fc1ccccc1-c1nc2cc3c(cc2[nH]1)OCCO3 +CCOc1cc(NC(=O)COc2ccccc2C#N)ccc1OC +COc1cccc(C2CC(Nc3cnn(C)c3)C2)c1 +CCn1cc(C#N)c(=O)n(CCOc2ccccc2C(C)=O)c1=O +N#Cc1ccccc1C(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +COc1cc(-c2cc(OC)c(N)cc2OC)c(OC)cc1N +CC(=O)Nc1ccc(NC(=O)N2CCOCC2C2CC2)cc1 +O=C(NCC(O)c1ccco1)C1(c2ccc(F)cc2F)CCC1 +Cc1noc(C)c1C(C)NC(=O)c1c(C)[nH]c2ccccc12 +CCC(C)NC(=O)Nc1ccccc1C(=O)N(C)C1CCCCC1 +CC(O)(CNS(=O)(=O)c1ccc(Cl)cc1)C1CC1 +CCc1cc(NCCC(=O)N2CCOCC2)n2ncnc2n1 +COC(=O)Nc1cccc(NCC(=O)NC2(C#N)CCCCC2)c1 +Cc1cc(S(=O)(=O)Nc2cn[nH]c2)c(C)cc1Br +COC(=O)C1=C(C)N(CC2CC2)C(=O)NC1c1cscn1 +COc1cccc(CNc2cccc(C(C)=O)c2)n1 +CC(=O)N1CCCc2ccc(NS(=O)(=O)C3CCCCC3)cc21 +CC(C)CNC(=O)NCCCNc1ncccn1 +O=C(NCc1cn2ccsc2n1)C1CCCCC1 +CCc1nnc(NC(=O)NC2CCOc3c(Cl)cccc32)s1 +COc1ccc(C(=O)N2CCCC(C)(C)c3ccccc32)nn1 +Cc1cccnc1CNS(=O)(=O)c1c(C)sc2ccccc12 +CCSc1nnc(SCc2ccccc2)n1N +COc1cc(O)c2c(c1)C(c1ccccc1F)NCC2 +O=C(c1cc(-c2cccs2)n(-c2ccccc2)n1)N1CCCC1 +CC1CCCC(NC(=O)Nc2cnc3c(c2)c(=O)n(C)c(=O)n3C)C1 +N#CC1(NC(=O)CSc2cccc(F)c2)CCCCC1 +COCc1ccccc1C(=O)Nc1ccc(C(=O)c2nccn2C)cc1 +CCC(NC(=O)Cc1nonc1C)c1ccc(F)cc1 +Cc1nnc(N2CC(OCCCn3cccn3)C3OCCCC32)s1 +CC(=O)C(C)Sc1nnc(-c2cccnc2)n1Cc1ccco1 +N#Cc1cccnc1N1CCN(CC(F)(F)F)CC1 +CCC(CO)NC(=O)c1nnn(-c2ccc(Cl)cc2)n1 +CSc1ccccc1NC(=O)c1csc(Nc2cccnc2)n1 +Cc1noc(C)c1S(=O)(=O)NCC#Cc1ccc(C(N)=O)cc1 +CCC(=O)Nc1cccc(C(=O)OCCOC)c1 +CC(C)OCCCNC(=O)C1CC(=O)N(C2CCCCC2)C1 +CC(C)(C)OC(=O)N1CCCn2nnc(CO)c2C1 +CNC(=O)CN1CCN(c2cccc(Cl)c2)CC1 +O=C(Cc1ccc(F)cc1)NCCc1nc(-c2ccc(F)cc2)c[nH]1 +N#Cc1cc(F)ccc1Cn1c(-c2ccccc2)noc1=O +CS(=O)(=O)c1ccc(NCC2CCCCC2)c(S(C)(=O)=O)c1 +Cc1ccnc2nc(C(=O)OC(C)C(=O)c3ccc(F)c(F)c3)nn12 +O=C(c1ccc2cccnc2c1O)N1CC2CC(O)C(O)CC2C1 +COCCn1cnnc1S(=O)(=O)Cc1ccccc1Cl +Cc1nn(C)c(C)c1C(=O)Nc1ccc(-n2ccnc2C)cc1 +Cc1nc(C2CN(C(=O)c3ccc4c(c3)CCCC4)CCO2)no1 +Cc1ccc(NC(=O)C(C)NC(N)=O)cc1C(F)(F)F +CCC(C)NS(=O)(=O)c1ccc2c(c1)CCCC(=O)N2 +CC(C)n1c(NCC(=O)N(C)C)nc2sc3c(c2c1=O)CCCC3 +CCSc1ccc(C(=O)N(C)Cc2nc3ccccc3n2C)cn1 +CC(C)NC(=O)CCN(CCC#N)c1ccccc1 +CCOC(=O)NC1OC(C(N)=O)C(O)C(O)C1O +O=C(CCc1ccsc1)Nc1cccc(NC(=O)C2CC2)c1 +Cc1ccn2c(=O)c(C(=O)Nc3cc(F)cc(F)c3)cnc2c1 +Cn1c(Cn2ccc3ccccc32)nc2cc(N)ccc21 +Cc1cccc2c1C(=O)NC(c1cn(-c3ccccc3)nc1C)N2 +Cc1cc(C)nc(N2CCCC(CN3CCCC3=O)C2)n1 +Cc1cc(C(=O)NCc2cn(-c3ccccc3)nn2)sc1C +COc1ccc(OCc2cc(C(=O)N3CCCC3)no2)c(Cl)c1 +COc1cc(C(=O)N2CCc3cc(F)ccc3C2)ccc1Cl +COCc1cccc(NC(=O)N(C)CC(=O)Nc2ccccc2)c1 +CCCC(=O)N1CCCC1C(=O)Nc1ccc(OC)c(OCC)c1 +CC(NC(=O)c1ccc(=O)n(C)n1)c1cccs1 +NC(=O)C1(CNC(=O)c2ccc(OCC3CC3)cc2)CCOCC1 +CCn1nc(-c2cccc(OC(C)C)c2)cc(C#N)c1=O +COc1ccc(C(C)(C)CNC(=O)NCC2CCOC2)cc1OC +N#Cc1ccccc1S(=O)(=O)NCc1ccccc1 +Cc1cccc(C(=O)Nc2sc(C)c(C)c2C(N)=O)c1 +COC(=O)Cc1cc(=O)n(-c2ccc(Cl)cc2)[nH]1 +O=C(Cc1cccc(O)c1)NC1(c2ccc(Cl)cc2)CCOCC1 +Cc1oc(C)c(C(=O)N2CCCC(c3cn[nH]c3)C2)c1C +O=C(NCCCn1ncccc1=O)c1cccc(C(F)(F)F)c1 +Brc1cccc(CN2CCOCC2)c1 +Cc1cccc(OCCNC(=O)CNC(N)=O)c1 +Cc1ccc(C)c(NC(=O)CNC(=O)CNC(=O)c2ccco2)c1 +Cc1ccc(-n2cnnc2SCC(=O)NCC(C)C)c(C)c1 +Cc1ccn2cc(C(=O)NCc3coc(-c4cccs4)n3)nc2c1 +CCc1ccc(C(=O)CSc2nc(-c3ccncc3)n[nH]2)cc1 +Cn1cccc1C(=O)OCC(=O)N1CCOCC1 +Cc1nc(-c2csc3ccccc23)nc(N)c1C +Cc1cc(C)n(-c2ccc(CNC(=O)NCC3(C)CCCC3)cn2)n1 +Cc1ccccc1C(O)CNC(=O)c1ccc2[nH]ccc2c1 +COc1cc(C#N)ccc1OC(=O)c1cccnc1OCC(C)C +Cc1sc2nc(-c3ccsc3)[nH]c(=O)c2c1C +CC(C)c1noc(CCC(=O)N2CCCc3cccc(F)c32)n1 +Cc1cc(F)ccc1-c1nccn1CCN(C)S(C)(=O)=O +COc1ccccc1S(=O)(=O)CC(=O)NC(C)C +O=C1NC(c2cc(F)c(F)c(F)c2)Nc2cc(Cl)ccc21 +CC(C)C1NC(=O)CN(C2CCN(C(=O)OC(C)(C)C)CC2)C1=O +CCOc1ccc2c(c1)CN(S(=O)(=O)N(CC)CC)CC2 +CCn1nc(C(=O)NCc2ccc(OC)cc2)c2ccccc2c1=O +Cc1cc(C(=O)NC(C)CC(=O)c2cccs2)n(C)n1 +CC(C)(C)c1ccc(C(O)CCCC(=O)NC2CC2)cc1 +Cc1cc2nc(C(=O)Nc3ccc(C)c(C)c3)cc(C)n2n1 +CC(C#N)CNC(=O)c1ccccc1SC(C)C +CC1CCC2C(C=CC(C)(O)C2(C)C(=O)CCO)C1 +CCc1ccc(CN(C)C(=O)C(c2ccc(F)cc2)N(C)C)nc1 +O=S(=O)(c1ccccc1Br)N1CCOCC1C1CC1 +CCc1ncnc(NC2CC2c2ccccc2)c1Cl +Cc1c(S(=O)(=O)c2ccc(F)cc2)c(N)n(CC2CC2)c1C +O=C(NCc1ccc(-n2ccnc2)c(F)c1)N1CCCC(O)C1 +Fc1ccc(-c2n[nH]cc2CN2CCOC3(CCC3)C2)cc1 +C=CCNC(=O)Nc1cc(Cl)ccc1OCC1CCCO1 +Cc1ccc(C(=O)OCC(=O)NC2CCCc3ccccc32)o1 +Cc1csc(=O)n1CCC(=O)NC(C)C(N)=O +CCCc1sc(C(N)c2ccccc2OC)nc1C +CN1CC(NC(=O)N(Cc2ccccc2)CC(F)F)CCC1=O +COc1ccc(OC)c(CNc2ccc(C#N)cn2)c1 +CCOc1ncccc1C(=O)NC(C)c1cccc(N2CCCC2)c1 +Cc1nc(CCNS(=O)(=O)c2cc(Cl)cnc2N)cs1 +CNC(=O)c1cccc(NC(=O)NCCNC(=O)CC2CCCC2)c1 +CC(=O)c1cc(Cl)ccc1OCc1nc(C2CC2)no1 +COc1cc(C#N)ccc1OCc1nnnn1Cc1ccccc1 +CC(C)Cc1nc(CSc2ccc(N)nc2)no1 +CCCCn1cnc2c(-c3ccccc3)cn(CC(N)=O)c2c1=O +Cc1ccsc1CN(C)Cc1nc2ccccc2c(=O)[nH]1 +COC(=O)C1CC(NS(=O)(=O)c2ccc(Cl)cc2)CN1C +CN(Cc1cc(Cl)cc(Cl)c1)C(=O)Cn1ccnc1 +CN(C)c1cc(C(=O)C(C#N)c2ccccn2)ccn1 +COC(=O)Cn1nc(CO)cc1-c1cccs1 +Cc1cccc(CS(=O)(=O)N2CCC(=O)CC2)c1 +CCn1cc(C(=O)N(C)c2cccc(C(C)C)c2)cn1 +Cc1ccc(CCNC(=O)C2CC(=O)OC23CCCCC3)cc1 +CC=Cc1ccc(OC(C)C(=O)NCC(F)(F)F)c(OC)c1 +Cc1nc(CNC(=O)COc2cccc(C(N)=O)c2)c(C)s1 +CCc1nc2cc(OC)c(OC)cc2n1CCC#N +CC(C)c1nnc2n1CC(NC(=O)CN(C)S(C)(=O)=O)CC2 +CN(C)C(=O)c1cc(N2CCCC2)nc2ccccc12 +CC1CN(C(C)C(=O)c2ccc(Br)cc2)C(C)CO1 +CCOc1ccc(-c2csc(NC(=O)c3ccn(C)n3)n2)cc1 +CC(=O)NCC1CCCN(C(=O)c2cccc(OCC(F)F)n2)C1 +CCOC(=O)N1CCC(NC(=O)CNC(=O)c2cccs2)CC1 +CCOCCCNC(=O)c1c[nH]c2ccc(C)cc2c1=O +CCOc1cc(Cl)ccc1C(=O)N1CCC(CC)(CO)CC1 +COCCn1ccc2cc(Nc3cc(C)nc4ncnn34)ccc21 +CCc1ccc(CN(Cc2cccnc2)C(=O)c2ccccn2)cc1 +CCOC(=O)c1c(C)oc2nc(C)nc(N(C)C3CCCCC3)c12 +Cc1noc(C)c1CN(C)C(=O)CN1CC(c2ccccc2)CC1=O +CC(C)c1csc(NC(=O)c2cc(Br)cn2C)n1 +O=C(c1ccoc1)N1CCC2(CC1)CN(c1ccsc1)C(=O)CO2 +CC(C)(C)c1ccc(OCCC(=O)NCCO)cc1 +COC(=O)Cn1c(C(C)O)nc2cc(O)ccc21 +NC(=O)c1cnc(NC(=O)c2ccc(F)cc2Br)s1 +Cc1ccc(Cl)cc1-n1ncc2c(NC(C)C)ncnc21 +C=CCNC(=O)C1c2ccccc2Sc2ccccc21 +CCc1ccccc1N1CC(C(=O)NCc2cccc(F)c2)CC1=O +Cc1ccc(F)c(NC(=O)COc2cccc(S(C)(=O)=O)c2)c1 +COC(=O)c1[nH]c(C)cc1NC(=O)CC1CCCC1 +CCCNC(=O)COc1ccc(OC)cc1C(C)=O +CCc1oc(-c2ccc(S(=O)(=O)CC)cc2)cc1CC#N +COc1cccc2c1OCC(NC(=O)c1sccc1C)C2 +CCCCC1(C)Nc2ccccc2C(=O)N1CCOC +CCOc1ccc(NC(=O)c2ccc3c(c2)OCCO3)c(C)c1 +CC(=O)c1c(C)[nH]c(C(=O)CSc2nc(C)cc(C)c2C#N)c1C +CN(Cc1cc(=O)[nH]c2ccccc12)C(=O)c1cccs1 +Cc1ccccc1COC1CCN(C(=O)NC(C)C2CCOC2)CC1 +Cc1ccc(=O)n(CC(=O)N(Cc2ccccc2)Cc2ccccc2)n1 +Cc1cc(C)n(CC2CCCCN2C(=O)CCc2cnn(C)c2)n1 +CCC1CCCCN1c1ncnc(NCCc2ccccc2)c1N +N#Cc1cccc(C(=O)NCCC2=CCCCC2)c1 +Cc1cc(C(=O)N2CCN(Cc3cccs3)CC2)no1 +CC(C)NC(=O)NCc1cccc(C(=O)NCc2ccco2)c1 +Brc1csc2cnc3cccnc3c12 +N#Cc1cncc(-c2cccc(Br)c2)c1 +NC(=O)c1cc(NCC(=O)N(Cc2ccccc2)C2CC2)ccc1F +COc1ccccc1C(NC(=O)c1cccc(F)c1)c1noc(C)n1 +C=CCNS(=O)(=O)c1ccc(C(=O)NCc2cccs2)cc1 +CC(=O)N1CCCC1c1ccnc(-c2ccccc2)n1 +Cc1cccc(Oc2ncccc2NC(=O)Nc2cnn(C)c2)c1C +CCn1c(SCc2ccc(C(=O)NC)cc2)nnc1C1CC1 +COc1c(C)cccc1C(=O)Nc1sc2c(c1C(N)=O)CCCC2 +COc1cccc(C(=O)N(C)Cc2ccc(Cl)cc2)c1 +COc1cccc(F)c1C(=O)N1Cc2cnc(C(C)(C)C)nc2C1 +COCCn1c(SCC(=O)c2ccc(F)c(F)c2)nc(C)c1C +Cc1nonc1NC(=O)c1ccc(OC2CCC2)cc1Cl +Cc1nnc(SCC(=O)c2ccc(Br)cc2)n1N +Cc1cccc(OCc2nc3n(n2)C(=O)CS3)c1C +CCN(Cc1csc(C2CCCCC2)n1)CC(C)C#N +N#CCCN(CC1CCC1)S(=O)(=O)Cc1noc2ccccc12 +Cn1cc(C(=O)Nc2ccnn2Cc2cnn(-c3ccccc3)c2)cn1 +Cc1nc(SC2CCCc3ccccc32)sc1CC(N)=O +O=C(NCCc1nc2ccccc2[nH]1)C1CC(=O)N(C2CCCC2)C1 +Cc1nc(COC(=O)Cc2ccc(F)c(F)c2)sc1C +CN(CCNC(=O)NCc1cscn1)C(=O)OC(C)(C)C +CC(C)(C)n1cc(C#N)cc1NC(=O)Cc1c[nH]c2ccccc12 +COc1ccccc1C1CNC(=O)C2NC(c3ncc[nH]3)N=C2C1 +CNC(=O)COC(=O)CN(C)C(=O)c1ccccc1 +CNC(=O)CN1CCOCC12CCN(c1ccc(C#N)cc1)CC2 +CCn1ncc(NC(=O)C2CCCCC2)c(N2CCOCC2)c1=O +NC(=O)CCC1CCCN(C(=O)c2ccnc(OC3CCC3)c2)C1 +CCn1c(=O)n(CC(=O)NC2(C#N)CC2)c2ccccc21 +CNC(=O)NCc1ccc(-n2nc(C)cc2C)cc1C(F)(F)F +Nc1ccc(SCC(=O)Nc2ccc(Cl)cc2)cn1 +COCCNc1nc2nonc2nc1N1CC2CCCC1C2 +Cc1ccc(CNC(=O)c2cnc(N(C)C)nc2)o1 +CC(NC(=O)C1CCCCC1)c1ccc(S(N)(=O)=O)cc1 +CC(=O)Nc1ccc(SCCN2CCOCC2)nn1 +CN(C)C(=O)N1CCN(C(=O)NCCc2c(F)cccc2F)CC1 +O=C(NCc1ccc(COCC(F)(F)F)cc1)c1cnns1 +Cc1cccc(CN2CCc3nc4ccc(F)cc4c(=O)n3CC2)n1 +CCNc1cc(S(=O)(=O)NC(C)(C)C(N)=O)ccn1 +Cc1cccc(OC2CCN(C(=O)c3ccc[nH]3)CC2)n1 +CC(=O)N1CCC(C(=O)NC(C)C(C)(C)C)CC1 +O=C(c1ccc(C#CCO)cc1)N1CCCCCC1 +COCCCNc1ncnc(NC2CCCC2)c1N +Cc1cc(NC(=O)CNC(=O)c2ccccc2Br)no1 +Cn1cnnc1C1CCCN(C(=O)CCc2cccs2)C1 +O=C(NCC1COc2ccccc2O1)c1cc(Cl)c[nH]1 +N#Cc1c(N)n(-c2ccccc2O)c2nc3ccccc3nc12 +O=C1COc2ccc(NC(=O)c3ccccc3O)cc2N1 +O=C(NCC(F)(F)F)C1CCN(c2ncccn2)CC1 +CC(C)(C)CC(=O)N1CCC(c2ccsc2)CC1 +NC(=O)CCN(C(=O)CCc1ccccc1Cl)c1ccccc1 +N#Cc1cccc(C(=O)C(C#N)c2nc3ccccc3[nH]2)c1 +O=C(OCC(=O)N1CCCC1)c1cccc(OCC(F)F)n1 +CN(CC(O)C1CC1)C(=O)C1(c2ccc(F)cc2)CCOCC1 +COc1ccc(Cl)cc1-c1n[nH]c(SC(C)C(=O)N(C)C)n1 +CC1CC(c2ccc(N)cc2)CCN1C(=O)OC(C)(C)C +c1ccc(CNCC2OCCc3cn(CC4CCOCC4)nc32)nc1 +Cc1ccc(C(C)C)cc1OC(C)C(=O)N1CCCS1(=O)=O +Brc1ccc(-c2cn(CCN3CCOCC3)nn2)cc1 +CCOC(=O)c1ccc(NC(=O)Nc2cccs2)cc1 +CCn1c(CC2CCN(c3ncnc4[nH]ccc34)CC2)nn(C)c1=O +COc1ccc(NC(=O)c2cn3ccc(C)cc3n2)cc1 +Cc1nc(C)c(CC(=O)NCc2cccnc2)c(=O)[nH]1 +C=CCOC1CC2COCC(C1)N2Cc1nccs1 +O=C(C1CCOCC1)N1CCN(Cc2cccc(F)c2)CC1 +COC(CNC(=O)CN(C)S(C)(=O)=O)c1ccccc1C +COc1ccc(Nc2nc(=O)[nH]nc2C)cc1OC +COc1cc(C(C)=O)ccc1OCC(O)Cn1nc(C)nc1C +CN(CC1CCCCC1)C(=O)c1ccc(-n2cncn2)cc1 +CCC1C(=O)NCCN1C(=O)c1ccc(-n2ccnn2)cc1 +CSc1nsc(SC)c1NC(=O)OCC1CCCO1 +CCC(CC)C(=O)N1CCCN(C(=O)OC(C)(C)C)CC1 +CCN(CC)C(=O)c1nc2c(s1)CCN(C(=O)C(C)C)CC2 +O=C(Nc1cccc2cccnc12)c1ccc(Cn2cccn2)o1 +COc1cccc(OCC(=O)Nc2cccc(N)c2)c1OC +CCS(=O)(=O)N(C)C(C#N)c1cccc(OC)c1 +Cc1cccc(C)c1NC(=O)c1cn(-c2ccccc2)nn1 +CCN(CC1CC1)C(=O)Nc1cccc(S(=O)(=O)N(C)C)c1 +O=C(Cc1csc(-c2ccco2)n1)Nc1nccs1 +O=C(Nc1cc(-c2ccc(F)cc2F)no1)c1cscn1 +O=C(NCCO)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ccc(OC(=O)CCc2cnn(C)c2)cc1C +Cc1noc(COC(=O)Cc2nc(-c3ccccc3)oc2C)n1 +Cc1ccccc1NC(=O)CN1CCN(Cc2cccs2)CC1 +COc1ccc(-n2nc(C)c3c2CCCC3=O)cc1 +CCc1cc(N)c2onc(CC(=O)Nc3cccnc3)c2c1 +CCc1nc(NC(=O)C2CCCN(C(=O)c3ccoc3)C2)sc1C +c1ccc(OCc2nc3ccccc3n2Cc2noc(C3CC3)n2)cc1 +CS(=O)(=O)NC1CCN(Cc2cc(-c3ccccc3)cs2)C1 +Cc1cc(N)ccc1NC(=O)CCCOCC1CCCO1 +Cn1ccc(NC(=O)c2ccccc2Oc2cccnc2)n1 +Nc1cc(NC(=O)c2cccc(C(F)(F)F)c2)ccc1F +O=C(NCCNC(=O)c1ccccn1)c1ccc(Br)cc1 +OC1CC(C(F)(F)F)Oc2ccc(Cl)cc21 +Nc1ccc(C(=O)c2cccc(Br)c2)cc1 +COC(=O)C1(N)CC(C)(C)Oc2ccc(Cl)cc21 +COC(=O)COc1ccc2c(=O)c(Cl)coc2c1C +CCc1nn(C)c(OC)c1CN1CCNC(=O)C1C(C)C +O=C1Nc2ccccc2C12CCN(S(=O)(=O)c1cccs1)C2 +Cc1ccc(NC(=O)C(C)C)cc1NCc1nc(C(C)C)no1 +CC1CCN(S(=O)(=O)NCC2CCCO2)CC1 +CC(=O)Nc1cccc(CNC(=O)NC2c3ccccc3CC2O)c1 +Clc1ccc(-c2nc(-c3ccc(-n4ccnc4)nc3)no2)cc1 +CCCCn1nc(C(=O)Nc2cccc(C)c2C)ccc1=O +Cc1cc(C)c(S(=O)(=O)N2CC(C)OC(C)C2)c(C)c1 +CCC(NC(=O)CNC(=O)c1ccoc1)C(C)C +Cc1n[nH]c2ncc(C(=O)NCCCOCC(C)C)cc12 +Cn1cc(C(=O)OCC(=O)Nc2ccccc2Cl)c2ccccc21 +CN(C)c1ccc(Cl)cc1NC(=O)CCNC(=O)C(C)(C)C +CNS(=O)(=O)c1cc(C(=O)Nc2ccc(C)cc2O)cc(C)c1C +Cc1ccc(N(C)C(=O)c2cnc3ccc(C)cn3c2=O)c(C)c1 +CC(C)CC(=O)Nc1nc(C(=O)NCc2ccccn2)cs1 +CCOc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1OC +O=c1cnn(-c2cc(Cl)cc(Cl)c2)c(=O)[nH]1 +CC(=O)N1CCC(NC(=O)NCc2ccncc2)CC1 +CCOC(=O)Cc1csc(NC(=O)c2ccc(OC)cc2)n1 +NC(=O)COc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1 +Cc1sc2ncnc(OCc3cc(=O)n4ccsc4n3)c2c1C +CCn1nc(C)cc1C(=O)NCc1c(C)nc2cc(=O)[nH]n2c1C +CCN1C(=O)Cc2cc(C(=O)Nc3ccccc3)ccc21 +Cc1ccc(F)c(CN2CC(=O)N3CCC(O)CC3C2=O)c1F +COC(=O)c1c(Cl)ccc(C)c1NC(=O)c1ccco1 +CC1CCCCC1NC(=O)CSc1nc2ccccc2c(=O)n1C +Cc1ccc(C(=O)NCCNC(=O)Cc2cccc(F)c2)cc1F +CC(=O)N(C)Cc1cccc(NC(=O)NCc2ccc(C)cc2C)c1 +COc1ccc(C(=O)C2CCN(c3ncccn3)CC2)cc1 +CC(C)CC(C#N)N(C)C(=O)c1c(F)cccc1Cl +CC(C)C(=O)NC(c1nc(-c2ccco2)no1)C(C)C +Cn1c(=O)c2c(ncn2Cc2ccccc2C(F)(F)F)n(C)c1=O +Cc1[nH]ncc1C(=O)N(CCC(F)(F)F)CC1CC1 +CC(=O)Nc1ccc(OC(=O)C23CCC(C)(C(=O)O2)C3(C)C)cc1 +CC(=O)N1CCOC2(CCN(C(=O)c3cnoc3C)CC2)C1 +Cn1c(=O)c2nscc2n(CC(=O)NC2CCCCC2)c1=O +O=C(NCC(O)c1c(Cl)cccc1Cl)C1CC=CCC1 +Cc1c(C(=O)NCc2ccccn2)nnn1-c1ccccc1 +CCNc1nnc(-c2nnc3scc(C)n23)s1 +CC(C)OC(=O)CSc1ccc(S(=O)(=O)N2CCCC2)cn1 +c1ccc(CSc2ccc(-c3ccccn3)nn2)cc1 +O=S(=O)(NC(C1CC1)C1CC1)c1ccc(Cl)cc1F +O=C(Nc1cccc(-n2ccnn2)c1)NC1C2CCOC2C12CCC2 +Cc1csc(NC(=O)c2cc(=O)[nH]c3ccccc23)n1 +COc1ccc(-c2oc3ccccc3c(=O)c2OC(C)=O)cc1 +NC(=O)COc1cccc(C(=O)N2CC3C4CCC(C4)C3C2)c1 +CCN(Cc1cccc(NCc2noc(-c3ccoc3)n2)c1)C(C)=O +Cc1cc(NC(=O)NCCc2ccc3c(c2)OCO3)n(C)n1 +COCC(C)N(Cc1ccc2c(c1)OCO2)C(=O)c1csc(C)n1 +Cc1ccc(CC(=O)N2CCCC(c3nn(C)c4nccnc34)C2)cc1 +Cc1cc(C)nc(N(C)CCOc2ccccc2)n1 +CC(C)(C)OC(=O)N1CCCC(c2cc(N)on2)C1 +COc1ccc(S(=O)(=O)N2CCCC(c3nncn3C)C2)cc1 +Cc1cc(F)ccc1NC(=O)N1CCCC(NS(C)(=O)=O)C1 +O=C(CNC(=O)c1cnccn1)NCCc1ccncc1 +CCOC(=O)N1CCC(Nc2ncc(Br)cn2)CC1 +CCOC(=O)c1cccc2nc(N)n(CC(=O)OC)c12 +Cc1cc(C)cc(OCCNC(=O)NCc2ccc(C(N)=O)cc2)c1 +CSc1ncc(CN2CCCC(OCc3cccnc3)C2)cn1 +CCCCn1nnnc1CN1CCCC1Cn1nc(C)nc1C +Cc1cc(C)n(C(C)C(=O)Nc2ccc(Br)c(C)n2)n1 +COC(=O)NCCOC(=O)c1cncc(Br)c1 +CCNC(=O)c1cccc(CNC(=O)NCCOC)c1 +Cc1cc(Br)c2ncc(CC#N)n2c1 +N#Cc1ccccc1OCC(=O)N1CCSc2ccccc21 +Cc1nc(C2CCN(C(=O)NCCc3ccc(F)cc3C)CC2)no1 +Cc1ccc2ncc(CN3CCN(c4cnn(C)c4)C(=O)C3)n2c1 +O=S(=O)(c1cccnc1)N(Cc1ccc(F)cc1)CC1CC1 +O=C(CCC1CCN(S(=O)(=O)CC(F)(F)F)CC1)NC1CC1 +CC(C)NC(=O)CN(C)C(=O)c1cccn1Cc1ccccc1 +COc1cc(F)c(C(C)NC(=O)C2(C#N)CCCCC2)cc1OC +Nc1cc(Cl)cc2c(C(=O)N3CCCCC3)nccc12 +Cc1cc(C)cc(C(N)C(=O)NCCCCCO)c1 +CC(C)CC(=O)N1CCCN(S(=O)(=O)c2ccccc2)CC1 +COC(=O)c1ccc(NC(=O)NCCC(C)C)cc1 +Cc1nc(-c2ccccc2)sc1NC(=O)N1CCCC1C(C)(C)O +CCc1cc(C#N)c(NC(=O)c2sc(COC)nc2C)s1 +OCCCc1nc2ccccc2n1CC(O)c1ccc(F)cc1 +CC(C)N1CCN(C(=O)C2CCN(C(=O)OC(C)(C)C)CC2)CC1 +Cc1n[nH]cc1CNCCc1nnc2ccccn12 +COCCOC(=O)Cn1c(=O)oc2cccc(N)c21 +CCCNC(=O)Cn1nnc(C(C)=O)c1-c1ccccc1 +N#CC(c1ccccc1)N1CCN(C(=O)c2ccc(C(N)=O)cc2)CC1 +c1cnc(-c2cnc(N3CCCCC3)nc2-c2ccoc2)cn1 +Cc1cnc(C(=O)Nc2ccccc2C(C)C)cn1 +CCCNC(=O)COC(=O)c1cc(-c2ccco2)nc2ccccc12 +O=C(COc1ccccc1O)Nc1cccc(O)c1 +O=C1CN(C(=O)c2nc(-c3ccccc3)oc2C2CC2)CCN1 +Nc1cccc2c1CN(c1ccccc1)S(=O)(=O)C21CC1 +Cc1noc(COC(=O)CNC(=O)CC(C)(C)C)n1 +CCCC1CN(C(=O)Nc2cccc(S(C)(=O)=O)c2C)CCO1 +CCn1cnnc1C1CCN(C(=O)c2ccc(OC(C)C)nc2)CC1 +CNC(=O)c1ccc(NC(=O)Cc2ccc(C(F)(F)F)cc2)cc1 +N#Cc1c(CN2CCOc3ccccc32)cn2ccccc12 +O=C(NCc1ccccc1-c1ccc(Cn2ccnc2)cc1)C1CCC1 +CCCc1noc(CN2CCc3ccccc3C2)n1 +COc1cccc(-c2nc3ccc(F)cn3c2C#N)c1 +C=CCC1CC=CC(C)N1C(=O)c1cnc(NCC)nc1 +CC1CN(C(=O)CS(=O)(=O)c2ccc(F)c(F)c2)CCO1 +COCCCNc1ncnc2c1Cc1ccccc1OC2 +O=C(Cc1ccc(Cl)cc1)NCc1cccnc1 +CC(C)COc1cc(C(=O)NCc2ccccc2)ccc1N +COc1ccc(S(=O)(=O)Nc2cnccc2C)c(C)c1C +CCCNC(=O)C1CCN(C(=O)NCCc2ccccn2)CC1 +Cc1ccc(C(=O)N(CCC#N)CCC(F)(F)F)cc1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2cc(C)ccc2C)cc1 +CCCCN(C)C(=O)NCc1cccc(CN2CCCC2=O)c1 +Cc1ccccc1-n1ccn(Cc2ccc3c(c2)OCO3)c(=O)c1=O +CCN1C(=O)CSc2ccc(C(=O)NCc3ccc(C)cc3)cc21 +Fc1ccc2c(c1)CC(c1nc(COc3ccccc3)no1)O2 +COc1cc2c(cc1OC)CCN(C(=O)c1cnn(C)c1)CC2 +Cc1ccc(C)c(NC(=O)COC(=O)c2ccccn2)c1 +COc1ccc(CNC(=O)c2cc(-c3cccnc3)on2)cn1 +O=C(CO)NCCC1CN(Cc2ccc3c(c2)OCCO3)CCO1 +CCCCNS(=O)(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +Nn1c(COc2ccc(F)cc2)nnc1SCC1CCCC1 +Cn1cnnc1SCC(=O)Nc1ccc(C(F)(F)F)cc1 +COC(=O)c1cc(CNC(=O)CCC2CCCC2)oc1C +COc1ccc(CNC(=O)c2ccc(-c3ccccc3)[nH]c2=O)cc1C +Cc1nnc(NC(=O)Cc2csc(Cc3ccccc3)n2)s1 +CC1(C)CC(=O)c2cc(C(=O)NCCC3=CCCCC3)c(=O)[nH]c2C1 +Cc1nc(CNCc2ccc(Cl)c(Cl)c2)sc1C +Cc1cc(OCC(=O)Nc2ccnc(C(=O)N(C)C)c2)ccc1Cl +Cc1nc(C)n(Cc2ncc(-c3ccc(Cl)cc3)o2)n1 +CCCC(O)c1cc(C)c2c(c1)C(NC(C)=O)CC(C)(C)O2 +N#Cc1ccc(Cn2nnn(-c3ccccc3)c2=O)c(F)c1 +CCc1cnc(C)nc1NCCCN1CCOCC1 +CC(CC(=O)c1ccco1)NC(=O)c1cccnc1N1CCCCC1 +Nc1nonc1-c1nc2ccccc2n1CC(=O)N1CCOCC1 +O=C(NCc1cccc(F)c1)c1coc(-c2ccccc2)n1 +O=C(Cc1ccc(F)c(F)c1)Nc1cccc2cn[nH]c12 +CCOCCOC(C)C(=O)Nc1ccc(C#N)cc1 +COCCN(Cc1ccccc1)C(=O)Cc1noc2ccccc12 +CCc1ccc(CNC(=O)c2ccccc2S(C)(=O)=O)s1 +CN(C)c1cc(C(=O)N2CCCC2Cn2cccn2)ccn1 +COc1cc(C(=O)NCc2coc(-c3cccs3)n2)ccc1C +O=c1n(Cc2cc(F)cc3cccnc23)nc2ccccn12 +CN(CCC#N)CC(=O)Nc1nc2ccccc2s1 +CCC(NC(=O)NCCC(=O)N1CCCC1)c1cccc(Cl)c1 +CC(C)c1cc(C(=O)NCc2cccc(CN3CCCC3=O)c2)n[nH]1 +NC(=O)c1ccc(NC(=O)Cc2csc(-c3cccs3)n2)cc1 +O=C(NCc1ccccc1COCc1ccccc1)Nc1cccnc1 +CC(C)c1cccc(C(C)C)c1NC1=NS(=O)(=O)c2ccccc21 +CCCn1cc(C(=O)N(CCO)Cc2ccccc2Cl)c(C)n1 +CCC1CCCN(C(=O)NCc2ccc(S(N)(=O)=O)cc2)C1 +CN(C)S(=O)(=O)NC(=O)CNC(=O)CC(C)(C)C +Cn1cc(-c2c(C#N)c(N)nc3c2CCc2[nH]ccc2-3)cn1 +Cc1cc(NC(=O)c2ccc(C(C)(C)C)cc2)no1 +C=CCN(CC1CCCCC1)C(=O)c1ccc(S(C)=O)cc1 +O=C(NC1CC1)c1ccccc1Nc1ccccc1 +CSc1nnc(NC(=O)NC2CCCCC2)s1 +COc1cccc(C(=O)NCc2ccc(-n3ccnc3C)nc2)c1F +COCc1nc(COc2ccccc2C)sc1CC#N +Cc1csc(S(=O)(=O)Cc2nc(-c3ccccc3)oc2C)n1 +Cc1nc(-c2c[nH]c(C(=O)NCC(C)(C)c3ccncc3)c2)cs1 +CSc1nc(C)c(CCC(=O)Oc2ccc(F)cc2)c(=O)[nH]1 +CS(=O)c1ccc(CNC(=O)OC(C)(C)C)cc1 +CC(=O)Nc1cc(NC(=O)c2cc(Cl)c[nH]2)ccc1F +CCC(c1ccncc1)N(C)C(=O)Cc1ccc[nH]1 +O=C(Cn1cnc(-c2ccc(Cl)cc2)cc1=O)NC1CC1 +O=C(COc1ccccc1)NCC1(N2CCOCC2)CCCCC1 +NC(=O)C1CCCCN1C(=O)Cn1nc(-c2ccccc2)ccc1=O +Cn1nc(C(=O)NCCc2nc3ccccc3n2C)ccc1=O +COc1cccc(CN2CC(n3nc(C)cc3C)C2)c1 +COc1cccc(C(=O)N(C)Cc2ccc(OC)c(F)c2)c1 +N#CCCCOc1cccc(NCC(=O)N2CCc3ccccc32)c1 +Cc1nnc(SCC(=O)N(C)CC(F)(F)F)s1 +CC(=O)Nc1ccccc1CN1CCOC2CCCCC21 +CCn1cc(CCN2CCN(C(=O)C(C)C)CC2)c2cccnc21 +CN(C)C(=O)CN(Cc1ccc(C#N)o1)CC(F)(F)F +CC(C)NC(=O)C1CCCN(S(=O)(=O)N(C)C)C1 +Cn1cc(C(=O)NCC(C)(O)c2ccccc2Cl)cn1 +COCCN1CC(C(=O)NCCC2CCCCCC2)CCC1=O +CC(=O)Nc1nc(CSc2ccc(Br)cc2)cs1 +COCC(=O)N1CCN(C(=O)NCc2ccc(F)cc2)CC1 +CC(=O)Nc1ccc(CC(=O)Oc2ccc(C#N)cc2)cc1 +Cc1ccc(NC(=O)c2ccc(-n3cncn3)nc2)c(C)c1 +CC(OC(=O)c1cc2c(s1)-c1ccccc1OC2)C(N)=O +Cc1cc(C)n(C(=O)CSc2nnc(C)n2N)n1 +Cc1nc(-c2cccc(NC(=O)NCc3cccs3)c2)no1 +CNc1ccc(Cl)c(C(=O)N(C)C(C)CC(C)C)n1 +OC1c2ccccc2Sc2ccc(Cl)cc2C1O +N#CC(NC(=O)Cc1cccs1)C1CCCCC1 +O=C(Nc1ccccc1OC(F)(F)F)c1cn2c(n1)CCCC2 +O=C(c1ccccc1)N1CCC(c2nnc(-c3ccccn3)o2)CC1 +Cc1csc(CN2CCC3OCCC3(C(=O)N3CCCC3)C2)n1 +Cc1nnc2ccc(N3CCN(c4ncnc5[nH]ccc45)CC3)nn12 +Cc1nn(-c2ccccc2)cc1CN1CC(=O)NC2CCCCC21 +COc1cc(C)c(COC(=O)CN)cc1C(C)C +CCOc1ccccc1NC(=O)c1c(F)cccc1F +CCN(CC)C(=O)c1onc(-c2cccc(F)c2)c1N +Cc1ccc(CN(C)C(=O)c2cnc(C3CCCO3)s2)s1 +Cc1cc(C)c(C#N)c(SCc2nccn2C(F)F)n1 +Cc1cnn(CC2CCCN2C(=O)c2cc(-c3ccco3)[nH]n2)c1 +CCOC(=O)c1c(NC(=O)C(C)C)sc(C(=O)NC(C)C)c1C +CSc1cccc(NC(=O)c2ccc(Cn3cncn3)cc2)c1 +CC(NC(=O)c1ccccn1)c1nc(-c2ccccc2)c[nH]1 +CCCNC(=O)CNC(=O)c1cc(OC)ccc1N +Cc1cc(CN2CCN(c3nccs3)CC2)on1 +CCCCNC(=O)NCc1ccc2c(c1)OCCO2 +CN(C)S(=O)(=O)N(C)C1CCN(c2ccc(Cl)cc2)CC1 +Cc1nc2ncnn2cc1C(=O)N1CCN(C)CC1 +CC(C)(C)c1nc(CN2CCCN(CC(F)(F)F)CC2)no1 +O=C(c1ccc2c(c1)OCO2)N1CCC(CN2CCOCC2)CC1 +CCOC(=O)C1(Cc2ccccc2C)CCCN(C(=O)COC)C1 +COC(=O)c1nc(-c2ccccc2Cl)[nH]c1C +O=C(NCCc1nnc2n1CCC2)N1CCC2(CCCCC2)C1 +CCCCn1c(SCCn2c(=O)oc3cccnc32)nc(C)c1C +CCNS(=O)(=O)c1ccc(OC)c(C(N)=O)c1 +COc1cc(C(C)=O)ccc1OCC(=O)N1CCc2ccccc21 +CCN(CC)C(=O)C(C)C1(O)c2ccccc2-c2ccccc21 +Nc1c(C(=O)Nc2ccccc2F)nnn1-c1ccc(Cl)cc1 +CC(=O)NC(CC(C)C)C1NCCc2c(O)ccc(C)c21 +Nc1cc(S(N)(=O)=O)ccc1SCc1ccccc1 +COC(=O)CCn1nc(-c2ccc(Cl)cc2)c2ccccc2c1=O +CN(C)Cc1cc(=O)c(O)cn1Cc1ccc(F)cc1 +O=C(NCCNc1ccc(C(F)(F)F)cn1)c1ccsc1 +Nc1nnnn1NCC=Cc1ccc(Cl)cc1 +Cc1nc(CCNC(=O)Nc2cnn(C)c2)cs1 +COC(=O)N1CCC(NC(=O)NCCCc2c(C)noc2C)CC1 +Cc1ccc(S(=O)(=O)n2nc(-c3ccc(F)cc3)cc2N)cc1 +CCCNC(=O)c1cn(C2CC2)c2cccc(N)c2c1=O +COc1ccc2cc(CCNC(=O)c3ccc(F)cc3)c(=O)[nH]c2c1 +Cc1noc(CNC(=O)C2CCCN2c2nc3ccccc3o2)n1 +Cc1ccc(CN(C)C(=O)C2Cc3ccccc3C(=O)O2)o1 +COc1ccc(NC(=O)N(C)CCC(C)C)cn1 +Cc1noc(C)c1S(=O)(=O)NCCN1CCOCC1 +O=C(NCc1cccnc1)N1CCN(C(=O)C2CCCO2)CC1 +O=C(c1ccc(Cl)cn1)N(CCc1ccccc1)C1CCOC1 +CC(C)S(=O)(=O)N(Cc1nccn1C(F)F)c1ccccc1F +CC(C(=O)c1c[nH]c2ccccc12)N1CCC(NS(C)(=O)=O)CC1 +COc1ccc2c(c1)nc(C#N)n2-c1ccc(C#N)cn1 +CC(C)NC(=O)NCCn1nnc2cc(C(=O)N(C)C)ccc21 +CC1CN(C(=O)C(C)NC(=O)CC2CCCCC2)CCO1 +CCOC(=O)CCOc1ccc(F)cc1Br +CCOc1cc(NCc2ccc3c(c2)OCO3)nc(C)n1 +CC(=O)NCCCN(C)c1cncc(Br)c1 +COC(=O)c1ccc(S(=O)(=O)N2CCC(=O)CC2)c(C)c1 +CCCCc1ccc(NC(=O)c2ccncc2)cc1 +Cc1ccc(NC(=O)CNC(=O)c2ccsc2)nc1 +Nc1ccc2[nH]c(-c3ccc4[nH]c(-c5cccnc5)nc4c3)nc2c1 +O=C(COC(=O)c1sc2ccccc2c1Cl)NCc1ccco1 +N#Cc1c2n(c(=O)n(Cc3ccc(F)cc3Cl)c1=O)CCC2 +Cc1nc(-n2nnc(CO)c2C2CCCO2)sc1C +Cn1cc(C(=O)Nc2ccc(Oc3ccc(C#N)cc3)cc2)ccc1=O +Cc1cnn(CCC(=O)N2CC(=O)Nc3ccccc32)c1 +COc1ccc(C(=O)N2CCOCC2C2CC2)cc1OC(F)F +Cc1noc(C2(NC(=O)CCc3ccccc3)CCCCC2)n1 +Cc1nc2cc(-c3noc(C=Cc4ccco4)n3)ccc2o1 +CCC(C)NC(=O)C1CCN(c2ccc3c(c2)OCCO3)C1=O +CNS(=O)(=O)Cc1cccc(CNS(C)(=O)=O)c1 +CC(NC(=O)Nc1ccccc1)C(=O)NC(C)c1ccccc1Cl +O=C(NCC(F)(F)F)c1ncc(-c2ccccc2)o1 +O=C(NCc1cccc(Cl)c1)c1cnn2c3c(cnc12)CCCC3 +C=CCNC(C(=O)OC)c1ccc(C(F)(F)F)cc1 +O=C(c1ccncc1F)N(Cc1ccccc1)CC1CCCO1 +Cc1cccc(C(C)CNC(=O)C(C(C)C)N2CCCC2=O)c1 +N#CC1(NC(=O)CNc2ccc(F)cc2Cl)CCCC1 +O=C(OCc1cc(-c2ccc3c(c2)OCCO3)on1)C1CC1 +CC(C)CNC(=O)C(C)Sc1nnnn1C1CCCCC1 +COCC(C)NC(=O)CN1CCN(c2ccccc2)C1=O +CCC(=O)NCC(=O)NCc1ccc(Oc2cccc(F)c2)nc1 +Cc1nc(NC(=O)C(C)n2ccnc2)sc1C +CCNC(=O)CN(CC)c1ccnc(C(C)(C)C)n1 +O=C(C1CC1)N1CC(F)C(OCc2nc3ccccc3[nH]2)C1 +COc1ccc(NC(C)=O)cc1NC(=O)c1cc(C)no1 +Cn1c(=O)oc2ccc(NCc3noc(-c4cccs4)n3)cc21 +Cc1ccc2c(c1)c(=O)c(-c1nc(-c3ccccc3C)no1)cn2C +NC(Cc1ccc(F)cc1)C(=O)NCc1ncc[nH]1 +CC(C)C(=O)N1CCC(c2cc(O)nc(-c3cnccn3)n2)CC1 +C=CCNc1ncccc1-c1nc(-c2ccc(OC)cc2)no1 +Cc1ccc(C(=O)Nc2cccnn2)cc1Br +CCC(NC(=O)NCC(C)(C)c1ccncc1)c1ccc(C)cc1 +CCn1c(CN(C)C(=O)c2ccccc2O)nc2ccccc21 +CC(Sc1nncn1C)C(=O)N1CCc2ccccc21 +Cc1cc(F)cc2c1CCNC2c1cccnc1C +CC1CN(Cc2coc(-c3cccc(F)c3)n2)CCO1 +N#CCCC(C#N)CN1CCOC(c2ccc(Cl)c(Cl)c2)C1 +CN(C)C(=O)c1ccc(C(=O)Nc2ccccc2F)cc1 +CC1CN(Cc2cccc(C#N)c2)CC(c2ccccc2)O1 +CCc1cnccc1C(=O)N1CCC(Sc2ccccn2)CC1 +CC(c1ccccc1)n1cnc2c(oc3ccccc32)c1=O +CNC(=O)C1Cc2ccccc2CN1C(=O)COc1cccc(F)c1 +COC(=O)c1ccc(-n2nnc(C(=O)OC)c2N)cc1 +COc1nccnc1N1CCC(NC(=O)c2ccco2)C1 +Cc1cc(C)cc(OCCNC(=O)c2ccc(C)o2)c1 +CCCNC(=O)C(C)n1nc(C)c2sc3ccccc3c2c1=O +Cc1cccc(-c2cccc(CNC(=O)N3CCC(C(N)=O)C3)c2)c1 +O=c1oc2ccccc2c2nc(N3CCOCC3)ncc12 +COc1cc(C)c(C(=O)CC(C)(C)C)cc1OC +N#Cc1ccc(CNC(=O)NCC(O)c2c(F)cccc2F)c(F)c1 +CC(O)(CNC(=O)c1nc2ccccc2s1)c1cccs1 +CC(=O)Nc1cc2c(cc1Br)-c1ccc(F)cc1C2=O +CCOc1cc(NC(=O)c2cc3ccccc3[nH]2)ccc1OC +O=C(NCc1ccc(-c2ccccc2)cc1)c1ccc2cncn2c1 +CCCc1c(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)[nH]c(C)c1C(C)=O +CN(CCn1cnnc1)C(=O)c1ccnc(OC2CCC2)c1 +CC1(C)OCC2(CO1)CN(C(=O)c1cnn3c1OCCC3)C2 +Cn1ccc(C(=O)Nc2ccnn2-c2cccc(Cl)c2)cc1=O +CCOc1ccc2nc3c(cc2c1)CN(Cc1cccnc1)C(=O)CO3 +Cc1ccc(N2CCCC(C)(c3ccccc3)C2)nn1 +COCCNC(=O)CCc1ccc(N2CCOCC2)c(N)c1 +COCC(C)NC(=O)NC(CN1CCOCC1)c1ccccc1 +O=C(NCc1ccc(F)cc1)c1ccc(CSc2ncn[nH]2)cc1 +Cc1nc(N)nc(-c2ccc(C(C)(C)C)cc2)c1C(=O)N(C)C +CC(=O)NCCNC(=O)c1cc(COc2ccccc2)[nH]n1 +Nc1cnc2[nH]nc(-c3cccc(Br)c3)c2c1 +O=C(CCc1ccc2c(c1)OCO2)NCCc1nnc2n1CCC2 +CC1CCN(C(=O)CCC(=O)Nc2nccs2)CC1 +CCc1noc(CC)c1CC(=O)Nc1sc(C)c(C)c1C(N)=O +O=C(c1cccc(-n2cnnc2)n1)N1CCc2ccccc2C1 +CC(C)CN1CCN(S(=O)(=O)c2ccc(F)c(F)c2F)CC1 +CC(=O)NCCc1csc(C2CCN(C(=O)C3CCC3)CC2)n1 +Cc1sc(NC(=O)Cc2cccs2)c(C#N)c1C +N#Cc1cnn2ccn(C3OC(CO)C(O)C3O)c12 +CC(C)(C)c1ccc(NC(=O)CSc2n[nH]c(=O)[nH]c2=O)cc1 +CC(CC(O)c1ccccc1)NC(=O)c1cccc2cccnc12 +COCCN(Cc1cnn(C)c1)C(=O)c1cc2c(s1)CCC(C)C2 +COc1ccc(C(=O)N(C)C)cc1NCC(=O)NC(C)C(C)C +Cc1cccc(C(C)CNC(=O)N2CCOCC2CC(C)O)c1 +CS(=O)(=O)N1CCN(C(=O)c2cc3sccn3c2)CC1 +CC1(C)Cc2cccc(OCCNC(=O)Cn3ccccc3=O)c2O1 +CN(Cc1cccc(C(N)=O)c1)c1cc(N2CCCC2CO)ncn1 +Cc1ccc(NC(=O)CSc2ccncc2)cc1F +CCOC(=O)c1cc(N2CCCC2CC)ccc1N +COc1cc(N2CC3CCN(c4ccc(C)nn4)CC3C2)ncn1 +CCCOc1ccc(-c2cc(CO)nn2CC(N)=O)cc1 +Cc1cc(NC(=O)COc2cccnc2C)n(C(C)(C)C)n1 +CCOCC(=O)OCC(=O)N1CCc2ccccc21 +O=C(c1ccsc1)N1CCc2ncnc(-c3ccccc3)c2CC1 +Cc1cccc(-c2[nH]ncc2CN2CCN(C(=O)C(C)O)CC2)c1 +Cc1nc(C)c(CC(=O)NCCN(C)c2ccccc2)c(=O)[nH]1 +COc1ccc(C2CCCN2C(=O)NC2CCC(O)CC2)c(OC)c1 +CC(C)n1cnnc1C1CCCN(C(=O)c2cccs2)C1 +COc1cccc(C(=O)CC(O)(C(F)(F)F)C(F)(F)F)c1 +CC(=O)C(C)Sc1nnc(-c2cccs2)n1-c1ccccc1 +COc1ccc(Cl)cc1NC(=O)c1cc2cc(F)ccc2n1C +O=C(Nc1ccccc1C(=O)N1CCOCC1)c1ccc(F)cc1 +O=C1c2ccccc2-c2nc3cc(Br)cnc3nc21 +CN(C)C(C(=O)NCC(=O)NC1CC1)c1ccc(F)cc1 +O=C(OCCc1cccnc1)c1ccc(-c2cscn2)cc1 +COCc1ccc(C(=O)Nc2ccc(CN3CCOC3=O)cc2)cc1 +COc1ccc(C)cc1Nc1ncnc(N2CCOCC2)c1N +Cc1nc2cc(NC(=O)CCC3Cc4ccccc4NC3=O)ccc2[nH]1 +Cn1c(=O)c2c(ncn2CC(=O)c2cc(F)ccc2F)n(C)c1=O +O=C(NCc1cc2ccccn2n1)c1cccc(C(F)(F)F)c1 +N#Cc1nnc2ccccc2c1NCC1CCCO1 +Cc1ccc(C(=O)NC2CCc3c(O)cccc32)cn1 +Cc1cccnc1CN(C)Cc1nc(C(C)C)cs1 +Cc1ccc(NC(=O)c2ccc(C(=O)N(C)C)cc2)cc1C(N)=O +Nc1nc(SCC(=O)N2CCC(c3ccccc3Cl)C2)n[nH]1 +COC(=O)c1ccc(CNC(=O)c2cc(=O)[nH]c3ccccc23)cc1 +CC(C)COc1nc(C(C)(C)C)nc(NC(C)C)c1N +CC(CNC(=O)c1ccc[nH]1)Sc1ccccc1 +COc1cc(C(=O)OC(C)C)ccc1OCc1cscn1 +Cc1sc(-c2ccn[nH]2)cc1NC(=O)c1ccncc1 +O=C(NCc1ccc2c(c1)OCO2)Nc1ccc(Cl)cc1 +CN(CCc1cccs1)C(=O)Nc1cnn(CC2CCCO2)c1 +Nc1ccc(C(=O)N2CCCC(C(F)(F)F)C2)cc1 +Cc1ccc(SCC(=O)Nc2ccn(C)n2)cc1 +FC(F)(F)COc1ccc(Br)cn1 +CCCCn1nc(-c2ccccc2OCC)cc(C#N)c1=O +CCc1ccc(OC)c(-c2cc(C(=O)OC)[nH]n2)c1 +CCN(CC)C(=O)CCc1nc(-c2cnn3c(C)cc(C)nc23)no1 +CCCNC(=O)Nc1ccc(-c2nccs2)cc1 +Cc1nn(-c2ccccc2)c2sc(C(=O)NCc3ccncc3)cc12 +CC(C)COc1ccccc1-c1cc(CO)c(=O)n(C)n1 +O=C(CSc1cc(N2CCOCC2)ncn1)Nc1cccc(F)c1 +CC(=O)NCCNC(=O)c1sccc1Br +OCCc1nc2ccccc2n1Cc1ccccc1 +O=C(NCCOCC(F)(F)F)Nc1cccc(Br)c1 +COC(=O)Cn1ccc(=O)c2cc(Cl)ccc21 +CC(=O)c1cc(F)ccc1OCC(=O)N1CCCCCC1 +CSc1ccc(CN(C)C(=O)CC2OC(=O)c3ccccc32)cc1 +C=CCNC(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +Cc1cccc(NCC(=O)c2ccc(C)c(N)c2)c1 +O=C(CC1OC(=O)c2ccccc21)c1ccc2c(c1)OCCO2 +COC(=O)c1ccc2c(c1)nc(CCO)n2C1CC1 +CCCc1cc(=O)[nH]c(SC(C)c2ncc(C)o2)n1 +Cc1noc2ncn(CC(=O)NCCc3ccccc3)c(=O)c12 +CSc1sc(C(=O)c2ccccc2)c(N)c1N +COc1ccc(NC(=O)c2ccc(C#N)cc2)c(OC)c1 +Cc1ccccc1CNc1ccccc1NC(=O)Cn1cnnn1 +c1ccc(N2CC3OCCN(c4cnccn4)C3C2)cc1 +O=C(NCCO)c1cccc(OCc2cccc3cccnc23)c1 +O=c1[nH]nc(-c2ccc3c(c2)CCO3)c2ccccc12 +CC(NC(=O)c1ccncc1F)c1ccc(-c2ccncc2)cc1 +C#CCN1C(=O)C(Cc2ccc(C)c(C)c2)Oc2cc(N)ccc21 +CCNC(=O)c1cccnc1N1CCN(c2ccc(F)cc2)CC1 +Nn1c(SCC(=O)NC2CC2)nnc1-c1ccccc1Cl +Cc1cccc(C(C#N)NC(=O)c2ccc3c(c2)OCO3)c1 +Cc1cccc(OCC(=O)OCc2cc(=O)n3oc(C)cc3n2)c1 +CCn1nnc(NC(=O)COc2ccc(C(C)C)cc2)n1 +Cn1ncc(Nc2ccc3nnnn3n2)c1C(F)F +CN(C(=O)Nc1cnn(CC(=O)NC2CCCC2)c1)C1CCC1 +COC(=O)C1(N(C)C(=O)c2cccc(-n3cccn3)c2)CCCCC1 +CCC1CNc2cc(S(=O)(=O)NC(C)C)ccc2O1 +CN(C)C(=O)C1CCN(C(=O)c2cccc(N3CCCC3=O)c2)CC1 +NS(=O)(=O)c1ccc(C(=O)N2CCc3cc(F)ccc3C2)cc1 +COc1ccc(Cl)c2sc(NC(C)=O)nc12 +O=C(Cc1cccs1)Nc1ccn(Cc2ccc(F)cc2)n1 +CNC(=O)CCCN(C)C(=O)Nc1cnccc1C +CC(=O)Nc1ccc(C)c(NC(=O)Cc2cccc3cccnc23)c1 +O=C(c1cc(=O)n(-c2ccccc2)[nH]1)N1CCOC(C(F)(F)F)C1 +CC1CCCN(C(=O)c2cccnc2-c2nc3ccccc3s2)C1 +CCC(C)(C)NC(=O)c1ccc(OC)c(OC)c1 +COc1ccc2oc(=O)c(C(=O)Nc3nc(C)c(C)s3)cc2c1 +CN(C(=O)c1ccc(CSc2ncn[nH]2)cc1)C1CCCCCC1 +CCCN(Cc1cccnc1)Cc1ccc(C#CC(C)(C)O)s1 +CC#CC(=O)NC1CC(=O)N(CCc2ccc(F)cc2)C1 +Cc1ccc(S(=O)(=O)N2CCC(Oc3cnccn3)CC2)cc1C +Nc1ccccc1NC(=O)CCCCCn1ccc(=O)cc1 +COc1ccc(CNC(=O)c2csc(NC(C)C)n2)cc1 +COc1ccc(NC(=O)NCc2nnc3n2CCC3)cc1F +CN(C)c1cc(C(=O)N2CCCC(c3cn[nH]c3)C2)c2ccccc2n1 +CCc1nsc(Nc2ccc(NC(=O)C(C)n3cncn3)cc2)n1 +CCC(C)NC(=O)C1CCN(S(=O)(=O)c2ccccc2C#N)CC1 +O=C1CCN(CCOc2ccc(F)cc2F)CC1 +O=C(c1ccsc1)N1CCc2onc(Cn3cccc3)c2C1 +CC1CCC(C(C)C)C(OCC(O)CN2CCOCC2)C1 +O=C(NCCc1cccnc1)N1CCN(c2ccccc2)CC1 +O=C(Nc1ccccc1SC(F)F)C1CCCO1 +CCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CC +CCn1cc(C(=O)N2CCN(Cc3ccco3)CC2C(C)C)cn1 +Cc1ccc(-n2ncc3c2ncn2nc(-c4cccs4)nc32)cc1 +CN(C)C(=O)c1ccc(NCC(=O)Nc2ccccc2Cl)cc1 +O=C(Cc1nc2ccsc2c(=O)[nH]1)Nc1ccccc1 +COc1cccc(CCC(O)c2cccnc2)c1OC +COc1cccc(-c2nnn(CC(=O)c3ccc[nH]3)n2)c1 +Cc1[nH]nc(O)c1CC(=O)N1CCC2(CCCN(C)C2=O)C1 +CN(CC(=O)NCC1CCOC1)S(=O)(=O)c1ccc(Cl)cc1 +COc1ccnc(N2CCn3c(cc4cc(F)ccc43)C2)n1 +CCN(CC(=O)NC(C)C)C(=O)c1cn2cccnc2n1 +O=S(=O)(Cc1ccc(OC(F)(F)F)cc1)NC1CCOCC1 +O=C(Nc1ccc2oc(C3CC3)nc2c1)c1ccncc1 +COc1cccc(C(CNC(=O)c2cc3ccccc3[nH]2)OC)c1 +N#Cc1cccc(NC(=O)Cn2cccnc2=O)c1 +CC1=CC(CO)C(C(C)C)CC1Cc1nnc(C)o1 +CCOc1ncnc2c1CN(CCS(=O)(=O)c1ccccc1)CC2 +CC(=O)Nc1ccc(OC(=O)Cc2cccs2)cc1 +COc1ccc(Br)c(NC(=O)c2cn3cccnc3n2)c1 +CC(NC(=O)CS(=O)(=O)c1ccccc1)c1ccc(F)cc1 +CCC1CCCC(NC(=O)NC(C)CCOC)C1 +CC(C)c1ccc(Cn2nnc(CO)c2C2CCCO2)cc1 +Cn1nc(C2CCCC2)nc1Cc1ccccc1N +CCCc1nc2[nH]c(-c3cccc4ccccc34)cc(=O)n2n1 +Cc1ccc(-c2n[nH]c(NC(=O)c3ccc4c(c3)OCCO4)n2)cc1 +CN(Cc1nccn1C(F)F)C(=O)Nc1ccc(Cl)c(Cl)c1 +CCNC(=O)c1cccc(CNC(=O)Nc2cnccc2C)c1 +COC(=O)c1ccc(N2CCOCC2)c(NC(C)=O)c1 +Cc1cc(-n2c(C)cc(C(=O)COC(=O)c3occc3C)c2C)no1 +CC(C)(C)NC(=O)N1CCC(CNC(=O)c2cccs2)CC1 +Cc1cccc(CCCOC(=O)Cn2ncc(=O)c3ccccc32)n1 +CCN(CC)C(=O)c1ccc(NC(=O)CCc2ccccc2N)cc1 +CC(C(=O)Nc1cc(C2CCCC2)nn1-c1ccccc1)n1cccn1 +CCCn1ccnc1Cn1ccnc1-c1ccsc1 +CN(CCOc1ccc(F)cc1)C(=O)c1cccc(C#N)c1 +Cc1nnc(NC(=O)CSc2nc(CC(C)C)n[nH]2)s1 +O=C(NCc1ccncc1)Nc1cccc(NC(=O)c2cc[nH]n2)c1 +CC(C(=O)N(C)C1c2ccccc2-c2ccccc21)n1cncn1 +CCCNC(=O)Nc1cccc(COCc2ccco2)c1 +Cc1ccc(NC(=O)C2CCCN2S(C)(=O)=O)cc1Cl +COc1ccc(NC(=O)NCCSc2nnnn2C)c(F)c1 +CS(=O)(=O)c1cccnc1C1CCCN(Cc2cccs2)C1 +CC(C)CN(CC(O)c1ccc(F)cc1)C(=O)c1cc(C#N)cn1C +Cc1ccc(C)c(C(=O)N2CCN(Cc3ccccc3)C(C#N)C2)c1 +CC1CCCN(c2ncnc(NCCc3cccs3)c2N)C1 +COCCc1noc(C2CC(=O)N(Cc3cccnc3)C2)n1 +COc1cccc(C(=O)NCc2n[nH]c3ccccc23)c1 +CCCCCNC(=O)C(N)c1ccc(Cl)cc1 +CCOCC(=O)N1CCSc2ccc(Cl)cc21 +Cn1c(=O)n(CCC(=O)Nn2cnc3ccccc32)c2ccccc21 +C#CCN1C(=O)COc2c(OCC)cc(CO)cc21 +Cc1sc2ncnc(N3CCCC(CO)C3)c2c1C +Cn1cc(C(=O)Nc2cccc(OCCc3ccccc3)c2)cn1 +CC(=O)Nc1ccc(F)c(NC(=O)N2CCOCC2)c1 +COC(=O)c1ccc(CSc2nnc(C)n2N)o1 +Cc1cc(C)nc(Nc2cccc(C(=O)NCCc3ccco3)c2)n1 +CS(=O)(=O)c1ccc(C(O)CN2CCOCC2)cc1 +O=C(CNC(=O)c1cccc(Br)c1)Nc1ccccc1O +CC(C)c1ncc(C(=O)NCCc2nc3ccccc3[nH]2)c(=O)[nH]1 +CC(C)(C)OC(=O)N1CCNCC1Cc1ccccc1C(F)(F)F +CC(=O)NC(C)C(=O)NC(c1ccccc1)c1ccc(Cl)cc1 +CC(=O)c1cc(CC(=O)NCc2cccc(F)c2F)cs1 +CC1CCN(S(=O)(=O)c2c(N)cccc2F)C(C)C1 +COC(=O)c1occc1CSc1nnc(-c2ccc(F)cc2)n1N +O=C(c1ccncc1)N1CCC(Cc2cccc3cccnc23)C1 +CCN1CC2(CCN(C(=O)C3(c4ccccc4F)CC3)CC2)OC1=O +NC(=O)c1c(NC(=O)CN2CCOCC2)sc2c1CCC2 +CN(CCc1ccccn1)C(=O)c1cc(F)ccc1Br +CC(=O)c1ccc(NC(=O)N(C)Cc2nc(C)cs2)cc1C +CC(=O)c1ccc(OCc2cccc3c2OCCO3)cc1 +CC(Sc1nnnn1C1CCCC1)C(=O)c1ccc(F)cc1F +Cn1cnc2cc(NC(=O)CCNC(=O)c3cnccn3)ccc21 +CC(=O)Nc1ccc(NC(=O)c2ccc(F)c(F)c2)cc1C +Cc1ccc(NC(=O)C2(C#N)CCCC2)cc1NC(=O)c1ccncc1 +CNC(=O)C1CCCN1C(=O)Nc1ccc(C(F)(F)F)cc1Cl +CCn1cc(NC(=O)C2CC(=O)N(C)C2c2ccc(F)cc2)cn1 +CCc1c(C2CCN(C(=O)c3ccn(CC)n3)CC2)noc1N +CN(Cc1nnc(C(=O)Nc2ccc(F)cc2)s1)c1ccccc1 +CC(C)CN(C)C(=O)C(C)NS(=O)(=O)c1ccccc1 +O=C(NCC1(c2ccccc2Cl)CCOCC1)N1CCOCC1 +CC(=O)NCC(=O)N1CCC2(CCC(=O)N2Cc2ccccc2)CC1 +CC(=O)N1CCC(C(=O)Nc2ccc(Br)cc2)CC1 +CC(c1ccccn1)N(C)C(=O)NCc1ccc2c(c1)CCC2 +Oc1ccc(CNc2cccc(F)n2)c(Cl)c1 +COc1cccc(C(=O)N2CCSc3ccc(N)cc32)c1 +COc1ccc(OC)c(C(CO)Cc2ccccc2OC)c1 +CCN(C(=O)c1cc(S(N)(=O)=O)c(C)o1)C1CCCCC1C +COCC(C)(NC(=O)C1CCOCC1)c1ccccc1 +COc1cccc(C(=O)NCC(=O)NC(C)(C)c2cccc(F)c2)c1 +c1cncc(-c2nnc3n2N=C(c2ccc4c(c2)OCO4)CS3)c1 +CCCn1nnc(C#N)c1-c1ccc(S(=O)(=O)N(C)C)cc1 +CC1(C)Cc2nc(-c3ccncc3)ncc2C(NC(=O)C(C)(C)C)C1 +COc1ccccc1NC(=O)Cn1c(=O)nc(N)c2cc(C)sc21 +O=C(c1ccccc1F)N1CCCC(c2cc3ncccc3cn2)C1 +NC(=O)c1csc(C(=O)Nc2ccc(Cl)cc2F)c1 +CC(=O)NCCNC(=O)Cn1nc(C)c2ccccc2c1=O +O=C(Nc1cccn(Cc2ccc(F)cc2)c1=O)N1CCCC(O)C1 +CC(C(=O)N1CCCCC1)S(=O)(=O)c1ccc2ccccc2n1 +Cc1nc(C(=O)NCc2cc(F)ccc2Br)cs1 +COCCOc1ccccc1CNc1ccccc1C +COC(=O)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +CCC(C)(C(=O)Nc1c(C)cc(C)cc1C)N1CCC1=O +Cn1c(SCC2CCCCC2)nnc1C1CC1 +COc1ccc(C)cc1C(=O)CCCC(=O)N1CCOCC1 +Cc1nc(NC2c3ccccc3CC2O)c2cccnc2n1 +Cc1ccccc1C1(CNC(=O)CC2C=CCC2)CCOCC1 +NC(=O)NCCC(=O)NC1CCCC(C(F)(F)F)C1 +COc1ccc(N2CC(C(=O)NC(C)Cn3cncn3)CC2=O)cc1 +CC(C)c1cc(C(=O)N2CCC3(CCC(=O)N(CCO)C3)CC2)[nH]n1 +O=C(CCC1CCCC1)Nc1ccc(N2CCNC2=O)cc1 +Cc1noc(C)c1C(=O)OCC(=O)NCC12CC3CC(CC(C3)C1)C2 +CCC(C)(C)NC(=O)CSc1nnc(C)n1-c1ccccc1OC +Cc1nc2ccccn2c1C(=O)NCC(O)(c1ccco1)C1CC1 +COc1ccc(OCC(=O)Nc2ccccc2C(=O)C(C)C)cc1 +COC(=O)c1ccc(CNC(=O)Nc2ccccc2C)cc1 +CC(NS(C)(=O)=O)C(=O)NC(C)C12CC3CC(CC(C3)C1)C2 +CC(C)c1ccc2c(c1)CCCN2CCCNS(C)(=O)=O +O=C(COCc1nc2ccccc2s1)NCc1ccccc1 +COC(=O)c1cc2c(=O)n(N(C)C)ccc2nc1C +Cc1cc(C)c2c(CNC(=O)c3ccccc3F)cc(=O)oc2c1 +Cn1c2ccc(F)cc2c2nnc(SCCN3CCOCC3)nc21 +Cc1csc(SCc2csc(-c3cnn(C)c3)n2)n1 +Cc1cc(C(F)(F)F)nn1CC(=O)NCc1ccccn1 +COc1ccc(C(=O)Nc2cc(F)c(F)c(F)c2)cc1OC(F)F +O=C(NCc1ccco1)c1ccc(CN2CCCC2=O)cc1 +CCN(CC)S(=O)(=O)c1ccc(C(=O)N2CCCC2)cc1 +COc1ccc(C(=O)N2CCn3c2nc2ccccc23)cc1 +O=C(NCCn1ncc2ccccc2c1=O)c1ccco1 +CN(Cc1cccc(C(F)(F)F)c1)Cc1ccnn1C +O=C(c1ccccc1NCCOc1ccc(F)cc1)N1CCOCC1 +CSc1ncnc(NCCn2cccn2)c1C#N +CCCCOc1ccc(CN2CCOC(c3cnn(C)c3)C2)cc1 +O=C(Nc1ccc2c(c1)COC2)N1CCCCC1CN1CCOCC1 +O=C1OCCN1CCn1cnc2sc3c(c2c1=O)CCNC3 +Cc1ccc(C(=O)N2CCN(c3nnc4cccc(C)n34)CC2)cc1 +Cc1cnc(C(=O)N2CC3COCC3(CNS(C)(=O)=O)C2)cn1 +CCCC(C)N(C)C(=O)c1ccc2c(c1)OCC(=O)N2 +O=C1CCCN1CCc1nc(-c2ccccc2)cs1 +CCCOCCOC(=O)c1ccc(Cl)c(N)c1 +NC(=O)CSc1nnc2c(=O)n(-c3ccccc3)ccn12 +c1cncc(-c2nc(NCc3ccncc3)ncc2-c2ccsc2)c1 +CCC(C(=O)c1ccc2c(c1)CCN2)N1CCN(C(C)=O)CC1 +CNC(=O)NC(C)(C)C(=O)NC1CCN(C(C)=O)CC1 +CC(C)(C)CCNC(=O)c1cccc(N2CCNC2=O)c1 +CC(=O)N1CCc2c(sc(NC(=O)C3CCC3)c2C#N)C1 +COCCNc1nc2c(c3n[nH]c(=O)n13)CCCC2 +N#Cc1ccc(NC(=O)CCN2CCOC(C3CCCO3)C2)cc1 +Cn1c(NC(=O)Cc2ccc(Cl)cc2)cc(=O)n(C)c1=O +Cn1nc2n(c1=O)CCN(C1CCCN(c3ccccc3)C1=O)C2 +O=C(Cn1cnnn1)N1CCN(C(=O)C2CC2c2ccccc2)CC1 +O=C(NCC(O)C1CC1)c1cc(F)c(Cl)cc1Cl +CCC(C)(CCO)NC(=O)NC1CCCN(Cc2ccccc2)C1=O +O=C(CCC1CCCO1)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(C)NC(=O)Nc1cccn(Cc2ccccc2)c1=O +CC1CN(CCCCNC(=O)c2cccc3[nH]ccc23)CC(C)O1 +Cc1ccc(CNc2nnc(-c3ccccc3)c(=O)[nH]2)cc1 +Cc1nccc(CNC(=O)N(CCC(F)(F)F)C2CCC2)n1 +CCC1CCCN(C(=O)Nc2ccc(OC)c(OCCOC)c2)C1 +CC(Cc1ccccc1Br)NCc1cnn(C)c1 +Cc1n[nH]c(C)c1NS(=O)(=O)c1ccc(O)c(N)c1 +Nc1cc(Cl)c(S(=O)(=O)N2CCNC(=O)C2)c(Cl)c1 +NC(=O)c1ccsc1NC(=O)CCSc1ccccc1 +O=C(c1ccc2cncn2c1)N1CCC(COc2ccccc2)CC1 +COCc1ccc(C(=O)NC(C#N)c2ccccc2C)cc1 +CCOc1cc(-c2noc(-c3cccnc3)n2)ccc1OC +CC(=O)N1CCc2cccc(NCc3ccc(C(F)(F)F)nc3)c21 +Cc1csc(NC(=O)CCCCNC(N)=O)n1 +CN(C(=O)C1COc2ccc(Br)cc21)c1ccccn1 +CCOc1ccc(C(=O)NCC(=O)N(C)Cc2ccc(F)cc2)cc1 +O=C(Cc1cn2ccsc2n1)NCc1ccccc1OCC1CC1 +COCCN(Cc1ccc(C)o1)C(=O)NCC#Cc1ccccc1 +COc1ccc(-c2nc(CN3C(C)COCC3C)cs2)c(OC)c1 +O=C(c1ccccn1)N1CCCC1c1nnc2n1CCCCC2 +Cc1cc(SCC(=O)C2=NC=CC2)nc2ccccc12 +COc1ccccc1S(=O)(=O)Nc1ccc2c(c1)nc(C)n2C +CCN(C)c1ccc(C(=O)N2CCN(Cc3cc(C)no3)CC2)cc1 +CCN(CC1CC1)C(=O)Nc1ccc(OC)c(-n2nnnc2C)c1 +CC(=O)c1ccc(N(Cc2nc(C)c(C)o2)S(C)(=O)=O)cc1 +CCN(CCC(=O)OC)C(=O)CN1CCCC1=O +COc1cccc(NCc2cc3cc(OC)ccc3[nH]c2=O)c1 +CNC(=O)c1ccc(CS(=O)c2ccc(OC)cc2)o1 +CN(Cc1ccco1)c1cc(=O)n2ccccc2n1 +Cc1ccc(-n2ncc3c(NCCCOC(C)C)ncnc32)cc1C +N#CCc1c(-c2ccc(Cl)cc2)nn2cccnc12 +O=C(CCn1ccc2ccccc21)N1CCN(c2nccs2)CC1 +Cc1ccc(CC(=O)N(CCC#N)Cc2ccco2)s1 +CCc1nnc(SCCC(=O)Nc2ccccc2OC)o1 +O=C(COc1cccc(Br)c1)NCCc1ccccn1 +CC(C)(C)OC(=O)N1CCC(C2C(=O)Nc3ccccc32)C1 +CCOC(=O)C1CCN(C(=O)CNc2cccc(C(C)=O)c2)CC1 +CC(C(=O)Nc1ccon1)n1ccc(C(F)(F)F)n1 +CCOc1ccc(C(=O)NC2CC(O)C(CO)C2)cc1OCC +CC1CCCN(C(=O)Nc2cc(F)ccc2F)C1 +N#Cc1ccc(S(=O)(=O)N2CCN(c3ncccn3)CC2)cc1 +Cc1[nH]ncc1CCCNC(=O)NC1CCOc2ccccc21 +COc1cc(OC)cc(C(=O)OC(C)C(=O)N2CCC(C)CC2)c1 +COCc1cccc(NC(=O)c2ccc(OC(F)F)c(OC)c2)c1 +Cc1n[nH]c(C)c1NC(=O)CN(C)Cc1nc2c(s1)CCCC2 +O=C(NC1CCC(O)CC1)c1cc(Cl)c2c(c1)OCO2 +O=C1CN(c2ccc(NC(=O)Cc3ccc(F)cc3)cn2)CCN1 +C#CCNC(C(=O)OC)c1cc(Cl)c2c(c1)OCO2 +Cc1ccnn1-c1ccc(C(=O)N2CCn3c(C)nnc3C2)cc1 +Cc1ccc(C(=O)NCc2noc(-c3cccs3)n2)cc1 +Nc1c(Nc2cccc(Cl)c2)ncnc1N1CCN(CCO)CC1 +CN(C1CCCCC1O)S(=O)(=O)Cc1c(F)cccc1Cl +CCC(=O)NC1CCCN(C(=O)C2CC2c2ccc(OC)cc2)C1 +COc1ccc(CNC(=O)CN2CCOCC2)cc1 +CCCCc1nc2cc(C(=O)NCc3nc(C)cs3)ccc2o1 +CCc1[nH]c(C(=O)Nc2ccc(OC)cc2)c(C)c1C(=O)OC +CC(C)CCCNC(=O)C1CCCCN1C(=O)c1ccccc1 +Cc1cc(C)n(-c2ccc(NCCNC(=O)C3CCCC3)nn2)n1 +CS(=O)(=O)N(CC(=O)Nc1cccc(F)c1)Cc1ccccn1 +O=C(Nc1ccc(N2CCCS2(=O)=O)cc1)C1CCCC1 +O=C(Nc1cccc(-c2noc(C3CC3)n2)c1)c1ccoc1 +C#Cc1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1 +COc1ccc(NC(=O)c2cccc(OCC(F)F)n2)cc1F +CC(C)CNC(=O)c1ccccc1NC(=O)COc1ccc(F)cc1 +CC(CCc1ccccc1F)C(=O)NCC1CN2CCCCC2CO1 +Cn1ncc(C(=O)Nc2ccccc2C(F)(F)F)c1N +COC(=O)NCc1ccc(NC(=O)C2CC2c2cccc(F)c2)cc1 +Cc1ccc(OS(=O)(=O)c2ccc(F)c(S(C)(=O)=O)c2)cc1 +CCN(C(=O)CCC(=O)OC)c1ccc(F)cc1 +CS(=O)(=O)N1CCCC(c2cccc(Cc3ccc(F)cc3)n2)C1 +CC1CCCN(c2nc3nc[nH]c(=O)c3s2)C1 +Cn1cc(C2CCCN2C(=O)c2ccc(N3CCOCC3)cc2)cn1 +Cc1ccnc(NCc2nc3c(C)cccc3o2)n1 +COc1ccc(Cl)cc1NC(=O)CCCNC(=O)c1ccccc1 +CCC(CC)c1nnc(NC(=O)c2ccc(-n3ccnn3)cc2)s1 +Cc1ccccc1CCNc1ncnc2c1cnn2CCC#N +Cc1cc(NC(=O)c2ccccc2N2CCOCC2)no1 +O=c1[nH]c(CNc2ccc(F)cc2)nn1CCc1ccccc1 +Cc1ccc(C(=O)NCCc2csc(C)n2)cn1 +Cc1ccc(NC(=O)CCOC(C)C)c(Br)c1 +Cc1ccc(S(=O)(=O)NC(CO)C(C)C)c(F)c1 +COc1cccc(C2(Cc3c(F)cccc3Cl)NC(N)=NC2=O)c1 +CCOC(=O)CNC(=O)c1nccc2c(N)ccc(Cl)c12 +CNC(=O)c1ccc(NC(=O)NC(C)c2ccc(F)c(Cl)c2)cc1 +CCc1ccc(NC(=O)NC(CCOC)C(N)=O)cc1F +COCC(=O)N1CCC(Oc2nncc3ccccc23)CC1 +COc1ccc(F)c(NC(=O)NCC2Cc3ccccc3O2)c1 +O=c1[nH]cnc(-c2ccccc2)c1Br +Cc1cc(COc2ccc(N)cc2Cl)n(C)n1 +CC(C)CCN(C)C(=O)CNC(=O)NCc1ccc(F)cc1 +COC(=O)C(Cc1ccccc1)NC(=O)Nc1ccc2c(c1)OCO2 +CC(C)CNC(=O)CS(=O)(=O)c1nnc(C2CC2)n1C +COC(=O)NCCCC(=O)NCc1nc(C)sc1C +Cc1cc(C)c(CNC(=O)C(NC(=O)C2CC2)C(C)O)c(C)c1 +O=C(Nc1cccc(OCc2ccccn2)c1)C1CC2C=CC1C2 +N#CCCN(CCC(F)(F)F)C(=O)c1ccc(C#N)cn1 +O=C(c1ncn(-c2ccccc2)n1)N(CC(F)(F)F)c1ccccc1 +O=C(c1ccc(-c2cccs2)[nH]c1=O)N1CCOCC1 +CCOC(=O)C1CCCN(C(=O)NCCCc2c(C)noc2C)C1 +COc1ccc(CN2CCOC(c3ccccn3)C2)cc1 +CC(OC(=O)c1ccc2c(c1)OCO2)C(=O)NC1CC1 +O=S(=O)(Cc1ccccc1Cl)N1CCC2(CC1)OCCCO2 +COc1ccccc1C1CC(=O)Nc2cc3c(cc21)OCO3 +C=C(C)COc1c(N)cc(C2OCCCO2)cc1OC +COc1cccc(C(=O)CCCC(=O)NC2CCCC2)c1 +CC1CCc2c(C(=O)N3CCC(CO)CC3)csc2C1 +COc1ccccc1NC(=O)NCCc1nncn1C(C)C +C=CCNC(=O)C1C(C)=NC(C(=O)OCC)=C1C +CC(Cn1cccn1)NC(=O)N1CCCc2ccccc21 +O=C(NC1CCOCC1)N1CCC(C(=O)N2CCCCCC2)CC1 +CCNC(=O)c1ccc(S(=O)(=O)NCC)cc1 +O=C(Nc1ccc(C(=O)N2CCCC2)cc1)Nc1cccc(Cl)c1 +CCC(C)C(NC(=O)c1ccc2c(c1)nnn2CC)C(N)=O +Cn1nccc1CNC(=O)N1CCCCCC1c1ccco1 +Nc1cc2c(=O)[nH]cnc2cc1SC1CCOCC1 +Cc1nc(C(=O)N(Cc2ccccn2)Cc2ccco2)c(C)s1 +O=C(c1ccc2c(c1)OCCO2)N1CCCCC1Cn1cccn1 +CCOc1ccc(F)c(C(=O)NCc2ccccc2F)c1F +COC(=O)CCNC(=O)CNC(=O)c1ccc(Cl)c(Cl)c1 +Cc1ncc(CNC(=O)Nc2nc(C3CC3)cs2)s1 +CCOc1cc(C(=O)NCC(=O)C(C)(C)C)[nH]n1 +COc1cc(C)ccc1NC(=O)c1n[nH]c(C)c1N +COc1cc(C#N)ccc1CNc1cnccc1C#N +Cc1c(CNc2nnc(Cc3ccc4ccccc4c3)o2)cnn1C +Cc1occc1C(=O)Nc1ccccc1S(=O)(=O)NC(C)(C)C +COC(=O)C1(N(C)C(=O)Cc2cccnc2)CCCCC1 +CCCC(=O)N1CCN(c2cccc(Cl)c2)CC1 +O=C(CCSc1ccc2c(c1)OCCCO2)Nc1ccc(F)cn1 +O=C(Nc1ccccn1)c1cccc2c(=O)c3cccc(F)c3[nH]c12 +O=C1CN(C(=O)c2ccc3ncccc3c2)CCN1 +CS(=O)(=O)c1ccccc1-n1cc(NC(=O)COCC2CC2)cn1 +COCCn1c(N2CCCC2)nc2c1c(=O)n(C)c(=O)n2C +c1cncc(-c2ncc(-c3cnccn3)c(-c3ccncc3)n2)c1 +Cc1nc(COc2cc3ccccc3cc2O)cs1 +O=c1[nH]c2ccccc2n1-c1ccc(C(F)(F)F)cc1 +CC1CC(c2ccsc2)CN1Cc1nnc(-c2cccs2)o1 +COc1cc(F)ccc1NC(=O)c1c[nH]c2cccc(F)c12 +COC1CCC2C1OCCN2C(=O)c1ccnnc1 +NC(=O)c1ccc(OCC(F)(F)C(F)F)nc1 +COCCCNC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 +CC(NC(=O)NCCN1CCOCC1)c1ccc(C(F)(F)F)cc1 +CCCCn1ncc(C)c1NC(=O)C1COc2ccccc2O1 +Cc1nc(C)c(C(=O)N2CCCc3c(F)ccc(C)c32)s1 +Cc1ccc(C)c(CC(=O)NCCNC(=O)c2ccccc2O)c1 +CSc1ccccc1NC(=O)NCC(C)(C)c1ccncc1 +Cc1cc(CNC(=O)c2sccc2C)ccc1F +O=C(Nc1ccc(F)cc1)c1cccc(N2CCCS2(=O)=O)c1 +Cc1ccc(N)c2c(Br)cnc(C#N)c12 +CC(NS(=O)(=O)N(C)Cc1ccc(Cl)cc1)C(N)=O +N#Cc1nnn(CCCCOc2ccc(Cl)cc2)c1C1CC1 +COCC(=O)Nc1ncc(Cc2ccc(OC(F)(F)F)cc2)s1 +Cn1c(C(=O)N2Cc3ccccc3CC2C(N)=O)cc2ccccc21 +COC(=O)c1ccc(NCC(=O)Nc2ccc(F)c(F)c2)cc1 +CCCC(C)NS(=O)(=O)c1ccccc1S(N)(=O)=O +COc1ccc2nc(NC(=O)CSc3nccn3C)sc2c1 +O=C(CC1CCCO1)NCc1cccc(C(F)(F)F)c1 +Cc1ccc(N)cc1Sc1nnc2n1CCCCC2 +O=C1CCc2ccc(NC(=O)N3CCCC(C(F)(F)F)C3)cc2N1 +Cc1cc(C(=O)NC(C)CCc2ccccc2)c2c(C)nn(C)c2n1 +N#CCCSc1nnc(-c2c[nH]c3ccccc23)n1C1CC1 +O=C(NC1CC1)C(Sc1ncccn1)c1ccccc1 +CN(Cc1nccn1C(F)F)C(=O)c1c[nH]nc1-c1ccccc1 +CC1Cc2ccccc2N1CCNC(=O)C1CC=CC1 +CCOc1ccccc1C(=O)NCC(O)c1ccc2c(c1)CCO2 +Cc1sc2ncnc(NCc3ccc(-n4ccnc4)nc3)c2c1C +CCOC1CCCN(S(=O)(=O)c2sc(=O)[nH]c2C)C1 +CCc1ccc(CNC(=O)c2nc[nH]c2C(=O)NCC(C)(C)C)cc1 +CC(Sc1nnnn1C1CC1)C(=O)NCC1(O)CCCCCC1 +Cc1ccc(NC(=O)N(C)CC2CCOC2)cc1S(C)(=O)=O +Cc1c(C(=O)N(C)CC(C)C#N)oc2c1C(=O)CCC2 +Nc1ccc(NCCNC(=O)CC2CCCCC2)nc1 +CN1CCN(C(=O)c2ccc(-c3ccc(F)cc3)s2)CC1 +CCCc1cc(C(=O)N2CC3CC(C2)c2cccc(=O)n2C3)[nH]n1 +O=C(NCCc1ccccc1)c1csc(-c2nc[nH]n2)n1 +CCOC(=O)c1cc(-c2ccccn2)nc(-c2ccccn2)c1 +COC1CCC(N(C)C(=O)c2ccc(C)cc2)CC1 +O=C(Nc1ccccn1)c1ccc2ccccc2c1O +CC1CCCN(C(=O)CN2CCc3ccccc32)C1 +CCCCn1c(=O)[nH]c(=O)c2c1nc(CN1CCOCC1C)n2CC +Cc1ccc(-c2n[nH]c(N(C)C)n2)c2cccnc12 +CCC(C)n1nccc1NC(=O)Cn1cnc2c(cnn2C)c1=O +O=C(CCC(=O)N1CCOCC1)Nc1cccc(N2CCCCC2)c1 +COc1ccc(OC)c(CCNC(=O)c2cnns2)c1 +Cc1oc2ncn(C)c(=O)c2c1C(=O)NCC1Cc2ccccc2O1 +O=C(Cn1ncc2ccccc2c1=O)N1CCN(c2ccccc2)CC1 +Cc1cccc(-n2nnc(CO)c2-c2ccccc2)c1 +C#CCNC(=O)c1ccc(=O)n(Cc2ccc(F)cc2C#N)c1 +Cc1cccnc1NC(=O)c1cccc(C(=O)Nc2ncccc2C)n1 +N#CCCn1c(CCNC(=O)c2ccccc2)nc2ccccc21 +CC1C(=O)NCCN1C(=O)c1ccc(Cl)cc1Cl +Cc1cc(C(=O)OC(C)c2nc3ccccc3o2)n(C)n1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1cn2c(n1)CCCC2 +Cn1cccc(NC(=O)c2csc(-c3ccsc3)n2)c1=O +Cc1cccc(CCC(=O)N2CCCN(Cc3nccn3C)CC2)c1 +N#CCCN(CCC#N)C(=O)COc1cccc(Br)c1 +CC(C(=O)N1CCOCC1)N1CC=C(c2ccc(O)cc2)CC1 +NC(C(=O)NCc1ccc2c(c1)OCO2)c1ccccc1 +CC(C)(C)NS(=O)(=O)c1cccc(S(C)(=O)=O)c1 +CN(Cc1ccncc1)C(=O)NCC(=O)N1CCc2sccc2C1 +CCOC(=O)c1cccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 +Cc1cccc(C(=O)Nc2ccc(Sc3nc(C)cs3)cc2)n1 +CC(C)CC(NC(=O)c1cnn2ncccc12)C(=O)NC1CC1 +CC(=O)Nc1nc2c(C)cc(NC(=O)c3ccncc3)cc2s1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)N2CC(C)OC(C)C2)c1 +Fc1cccc(COc2nc3ccccc3n3nnnc23)c1 +Cn1c(C2CC2)nc2cc(NC(=O)c3ccccn3)ccc21 +COc1ccnc(NC(=O)COc2ccc3ccccc3c2)c1 +CC(=O)N(C)CC(=O)NCCCOc1cccc(C)c1 +CS(=O)(=O)Nc1ccc(-c2ccc(NS(C)(=O)=O)cc2)cc1 +Cn1ccc(C(=O)COc2cccc(Br)c2)c1 +CCc1ccc(CNC(=O)Cc2nnc(-c3ccncc3)o2)cc1 +COc1cccc2c1OCC(Cc1ccc(C(=O)N(C)C)cn1)C2 +O=C(NCc1ccccc1Cn1cncn1)c1ccc(Cl)cc1 +Cc1ccncc1NC(=O)NCCc1nnc(-c2ccccc2)o1 +CC(=O)Nc1cccc(C(=O)OCc2cc(C)no2)c1 +COc1cc(C(=O)N2CCC(CCn3cccn3)CC2)ccn1 +CC(=O)N1CCc2cc(NC(=O)Cc3ccccc3F)ccc21 +CC(C)NC(=O)c1cccc(NC(=O)CCc2cccc(N)c2)c1 +Cn1ncc(Cn2cnc(C3CCC3)cc2=O)c1C(F)(F)F +CC(C)Oc1ccc(S(=O)(=O)N(C)CCO)cc1 +CCCC(C)NC(=O)C(C)S(=O)(=O)c1ccccc1F +COc1ccc(C2CC(O)=Nc3c2cnn3C(C)(C)C)c(OC)c1 +O=C(Nc1ccc(-n2cnnn2)cc1)c1cc(-c2ccc(F)cc2)[nH]n1 +Cc1cccc(CCNC(=O)Cn2cnc3c(cnn3C)c2=O)c1 +CCOC(=O)C(O)c1c(-c2ccccc2)cnn1C +Cc1cc(C(=O)N2CC(=O)Nc3ccccc32)nn1C +CCCCN(C)C(=O)CCC1=C(C)C(C(=O)N2CCOCC2)C(C)=N1 +CC(C)(C)NC(=O)Cc1csc(-c2ncccn2)n1 +CCCC(=O)NCC(=O)NC1CCN(c2c(F)cccc2F)C1 +CCCc1nnc(NC(=O)Cc2ccc(NC(C)=O)cc2)s1 +COC(=O)c1cc2cc(NC(=O)c3cc(C#N)c[nH]3)ccc2o1 +CCCc1[nH]nc(-c2ccc(C)cc2C)c1NC(=O)COC +CN(CCn1ccnc1-c1cnccn1)c1ccccc1 +Cc1ccc(=O)n(CC(=O)NCc2ccnc(OC3CCC3)c2)n1 +CN(C)C(=O)CN(C)C(=O)Cc1csc(Cc2ccccc2)n1 +O=C(Cc1ccccc1)NCC(=O)OCc1ccccc1Cl +COc1c(N)cc(C(=O)c2cccc(N)c2)c(O)c1OC +O=C(Cn1cnc2sccc2c1=O)Nc1cccc2ccccc12 +CN(C)C(=O)COCc1noc2c1CN(S(C)(=O)=O)CC2 +CNC(=O)c1ccc2c(c1)S(=O)(=O)N(C1CCCCC1)C2=O +COC(=O)c1ccc(CSc2nnc(C3CC3)n2C)cc1 +c1coc(CCNCc2c[nH]nc2-c2cccs2)c1 +O=C(NCc1noc(-c2ccco2)n1)c1cc(=O)[nH]c(=O)[nH]1 +COc1cc(F)ccc1NC(=O)c1cccc(OC)c1F +Cc1nc(NCCOc2nonc2C)c2nc(C)oc2n1 +Cn1cc(C(=O)Nc2ccccc2C#N)c(=O)c2cc(F)ccc21 +CCc1nc(CNC(=O)C(C)OCc2ccccc2)cs1 +O=C(Nc1ccc2[nH]ncc2c1)c1cc(F)ccc1F +O=C(COC(=O)Cc1ccsc1)NC1CCc2ccccc21 +CCN(Cc1ccccc1Cl)C(=O)Nc1ccccc1CC(N)=O +CC(C)(C)Oc1cc(CNC(=O)NCC2(C3CC3)CC2)ccn1 +O=C(OCc1ccccn1)c1csc2c1CCCC2 +COC(=O)C1CCN(C(=O)c2cc(Cl)ccn2)c2ccccc21 +Cc1nc(-c2c[nH]c(C(=O)NC(C)C3CC3)c2)cs1 +CCc1nc(CC(=O)NCC#Cc2ccccc2)cs1 +COCCn1c(C(=O)Nc2ccc3c(c2)COC3)cc2ccccc21 +O=C(NCc1ccccc1)n1ncc2ccccc21 +CC(C(=O)Nc1ccc(CC#N)cc1)n1c(=O)oc2ccccc21 +CCC(C)C(CO)NC(=O)Cc1c(C)c2c(O)cc(O)cc2oc1=O +Cc1ccc(NC(=O)CCc2nc3ccccc3[nH]2)cc1 +COc1cc(C(=O)Nc2ccc(C)c(N)c2)ccc1C +CCOC(=O)c1cc(S(=O)(=O)N2CCCC2)c(C)n1C +Cc1noc(C)c1CN(C)C(=O)NCc1cccc(NC(C)C)c1 +CCNC(=O)c1ccc(NC(=O)N2CCOCC2C2CC2)cc1 +N#CC(CCC(=O)N1CCCCCC1)c1ccco1 +O=C(CC1CCCC1)N1CCn2cc(Cn3cccn3)nc2C1 +CC(=O)NCC(=O)c1ccc(C2CCCCC2)cc1 +CCOCCCn1c(C)nc2cc(C(F)(F)F)ccc21 +CC(C)(C)c1nc(CNc2cnn(-c3ncccn3)c2)cs1 +Cn1ncc2c1CCCC2NC(=O)c1cc2c([nH]c1=O)CCC2 +CCC1CCCCN1S(=O)(=O)c1cc(F)ccc1F +COc1ncccc1CNS(=O)(=O)c1ccc(F)cc1 +COc1c(C(=O)N2CCC(C)CC2)nnn1Cc1ccccc1Cl +CCCCOc1ccc(C(=O)Nc2ccn(C)n2)cc1 +COc1ccccc1CNC(=O)COC(=O)c1ccoc1 +Cc1ccc(NC(=O)CNC(=O)c2c[nH]c3ccccc23)cc1F +Cc1cc(F)ccc1S(=O)(=O)Oc1ccc(-n2cnnn2)cc1 +COc1cncc(N(C)C(=O)OC(C)(C)C)c1OC +COc1ccc(OCCC(=O)C(C#N)c2ccccn2)cc1 +NC(=O)C(NC(=O)CC1CCCC1)c1ccccc1 +CCCC(=O)NCC(=O)Nc1ccc(C(C)=O)c(C)c1 +CC1CCCCN1C(=O)Cn1c(-c2cccs2)noc1=O +O=S1(=O)CCC(Sc2ccccc2)c2ccsc21 +Nc1cc(=O)[nH]c(SCC(=O)NCC2CC2)n1 +Cc1ccnc(NC(=O)Cn2ccc(=O)c3cccc(F)c32)c1 +C#CCNC(=O)c1ccc(=O)n(Cc2noc(CC)n2)c1 +COc1cccc(CC(=O)OCc2ccccn2)c1 +COc1ccc(NC(=O)c2n[nH]c3c2CCc2ccccc2-3)cc1 +O=C(Nc1cccc(-c2nc[nH]n2)c1)C1(c2ccccc2)CCOCC1 +Cc1ccc(-c2cc(CNC(=O)c3ccc(=O)[nH]c3)on2)cc1 +C=CCNc1ncc(C(=O)Nc2cc(OC)ccn2)s1 +Cc1ccsc1CCCC(=O)N1CCC(C(N)=O)c2ccccc21 +CCOc1ccc(N)cc1C(=O)N1CCCCCC1 +CCC(CC)(CO)NC(=O)Cc1ccccc1Cl +Cc1sc2nc(CN3CCOc4ccccc43)[nH]c(=O)c2c1C +O=C(Nc1ccc(OC(F)F)cc1OC(F)F)c1ccncc1F +CC(=O)NCCc1ccc(C(=O)CSc2ccc(C)cc2)s1 +CCCC1CN(C(=O)Nc2ccc(-n3cccn3)cc2)CCO1 +Clc1ccc(CN2CCN(Cc3cncs3)CC2)nc1 +Cn1cnnc1C1CCN(C(=O)c2cc3c(s2)CCCCC3)CC1 +CN(Cc1ccc(O)cc1)C(=O)CCCc1cccs1 +CCCc1nc(COC)sc1-c1nnc(NCC)s1 +O=C(CCn1cncn1)NC(c1ccc2c(c1)OCCO2)C1CC1 +COCc1nc(C2CCCN(c3cnccn3)C2)no1 +CCN(C(=O)Cn1ccnc1)C(C)c1ccc(C#N)cc1 +CS(=O)c1cccc(NC(=O)N2CCc3cc(F)ccc3C2)c1 +CC1CCC(C(N)=O)CN1C(=O)Nc1ccc(Cn2cccn2)cc1 +NC(=O)c1ccc(OS(=O)(=O)c2ccc(Cl)c(Cl)c2)cc1 +Cc1nc(C(C)Nc2ccc(=O)n(C)c2)c(C)s1 +CC(=O)Nc1cccc(NC(=O)CNC(C)c2ccccc2Cl)c1 +COc1ccc(NC(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1 +CC(NC(=O)Cn1nnc(-c2ccc(Cl)cc2)n1)c1ccccc1 +COC(=O)c1ccc(OCC(=O)c2ccc(NC(N)=O)cc2)cc1 +CC(NC(=O)N1CCCC1)c1cccc(N2CCCC2)c1 +COc1ncccc1Cn1c(=O)[nH]c2ccccc2c1=O +Cn1nnnc1SCC(=O)Nc1cccc(O)c1 +CCCn1c(C)nnc1SC(C)C(=O)Nc1ccc(C(N)=O)cc1 +O=C(c1ccccc1)N1CCN(C(=O)c2ccccc2F)CC1 +CC(Cn1cccn1)NC(=O)N1CCN(c2ccccc2O)CC1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cc(F)cc(F)c3)cc12 +CCC(=O)Nc1cc(S(=O)(=O)NC2CCCCC2)ccc1OC +CCN1CCNC(=O)C1CC(=O)OCc1ccccc1 +COCCCNC(=O)Nc1ccnc(Oc2ccccc2)c1 +CCC(C(=O)N1CCCCC1)N1C(=O)CCn2nc(C)cc21 +O=C(NC1CC1)c1ncc(Cl)c(Cl)c1Cl +O=C(CNC(=O)C1(c2ccccc2)CC1)Nc1cn[nH]c1 +O=C1CCc2cc(C(=O)Nc3ccnn3C3CCCC3)c(F)cc2N1 +CCC(C)NC(=O)CSc1nnc(-c2ccc(Cl)cc2)n1N +COc1cccc(C(=O)Nc2cccc(C(N)=O)c2)c1OC +CCc1n[nH]c2c1CN(C(=O)Cc1cnc3ncnn3c1)CC2 +CCN(CC(C)C#N)C(=O)CNc1cc(NC(C)=O)ccc1Cl +Cn1nc(C(=O)Nc2ccc(Br)cc2)cc1C(F)(F)F +CC(C)CN1CC2CN(C(=O)C3CCCO3)CC2C1=O +CCCn1c(CN2CCCN(C(=O)CC)CC2)nc2ccccc21 +Cc1nc(NC(=O)C(C)N2CCN(CCO)CC2)sc1C +Cn1cc(C(=O)OCC(=O)N2CCOCC2)c(-c2cccs2)n1 +CCOC(=O)CCNC(=O)Nc1ccc(Cl)cc1Cl +CCOC(=O)c1cnn(C(C)CC)c1C(F)(F)F +CCN1CC(C(=O)NC(C)c2ccc(Br)cc2)CC1=O +CC(=O)c1ccc(C(=O)N(C)Cc2ccc(F)cc2)s1 +CC(Nc1ccc(S(N)(=O)=O)cc1)C1CCCO1 +Cc1sc2ncn3nc(-c4ccco4)nc3c2c1C +O=C(OCC(=O)N1CCCC1)c1ccc(COc2ccc(F)cc2)o1 +COc1cccc(CNC(=O)c2cc3cccc(OC)c3o2)c1 +COCCCNC(=O)c1cccc(Nc2ncccn2)c1 +Cc1cc(C)cc(NC(=O)Cc2nnc(-c3sccc3C)o2)c1 +COc1cnc(N(C)Cc2ccccc2)nc1-c1ccnn1C +CCOC(=O)CN(C(=O)c1cc2ccccc2n1CC)C1CC1 +O=c1cc(-c2ccc3c(c2)OCO3)nc2n1CCCCC2 +CC(NC(=O)Cc1cccc2cccnc12)c1ccccc1 +CCCCNC(=O)C(C)N1CCN(C(=O)CC(F)(F)F)CC1 +COc1cc(N)c2ccnc(C(=O)N3CCCCC3)c2c1OC +N#CC1(NC(=O)C2CCC(NC(=O)CC3CCCCC3)CC2)CCC1 +CN(Cc1nc2ccccc2[nH]1)C(=O)c1ccoc1 +Cc1nnc(CN(C)Cc2ccc(OC(F)(F)F)cc2)n1C +CCC(NC(=O)Nc1cc(-n2cnnn2)ccc1C)c1nccs1 +CNc1snc(C)c1C(=O)NCC1COc2ccccc2O1 +COc1cc(NC(=O)NC2c3ccccc3CC2O)cc(OC)c1 +CCS(=O)(=O)c1nnn(CCCC(=O)OC)c1N +COc1cc(C(=O)NCC#Cc2ccccc2)cc(Cl)c1OC +Cc1ccc(OCc2nnc(SCCC#N)o2)cc1 +CN(Cc1cnc(N(C)C)nc1)C(=O)C(O)c1ccccc1 +O=C(NC1CCCc2[nH]c(=O)ccc21)C1(c2ccc(F)cc2)CCC1 +COc1ccccc1OCCN(C)C(=O)c1ccc2cc[nH]c2c1 +Nc1nccnc1C(=O)Nc1ccc(Cl)c(OC(F)F)c1 +CN(CCO)C(=O)NCc1ccc(Oc2ccc(F)cc2)cc1 +CC(=O)N1CCc2cc(C(=O)Nc3ncc(C(N)=O)s3)ccc21 +Nc1cc(C(=O)N2CCC3(CC2)OCCCC3O)ccn1 +O=C(NCC(=O)c1ccco1)c1cc(-c2cccs2)n[nH]1 +CCC(C)C(C)NC(=O)Nc1cc(NC(C)=O)ccc1F +CC1CC(C)CN(C(=O)NCCNC(=O)c2ccccc2)C1 +CCOc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1OC +O=C(N=c1ccccn1Cc1ccccc1)c1ccc[nH]c1=O +CN(C)c1ccc(C#CCNC(=O)c2ccc3[nH]ccc3c2)cc1 +CCn1nc(C(=O)NCCC(C)C)c(=O)c2ccccc21 +CNc1nn(-c2nc(C)cc(C)n2)c2c1C(=O)CC(C)(C)C2 +O=C(NCCNc1ncccn1)OCC(F)(F)F +CC(=O)N1CCN(C(=O)c2cnc(C)c(N)c2C)CC1 +Cc1ccc(CCCC(=O)N2CCC3(CC2)OCCO3)cc1 +CCOc1ncccc1CNC(=O)Cc1c(C)nc(C)[nH]c1=O +Cc1nc(Cc2nnc(SC(C)C(=O)N(C)C)o2)cs1 +CC1CCCCN1C(=O)Cn1c(S(C)(=O)=O)nc2ccccc21 +CCSc1cc(C(=O)NCC(O)c2c(F)cccc2F)ccn1 +CC(C)N1CCN(C(=O)Cn2cnc(N)n2)CC1 +C=CCn1cc(CO)c2c(OC)c(OC)c(OC)cc21 +O=C(NCC(F)(F)F)c1cccnc1N1CCOCC1 +CC(C)Oc1ccc(NC(=O)N(C)Cc2ccco2)c(F)c1 +O=C(COCC(F)(F)F)OCC1CCCCO1 +CCOCCNC(=O)N1CCC(N2CCOC(C)C2)CC1 +Cc1cc(NC(=O)c2ccn(COc3ccc(F)cc3)n2)no1 +O=C(NCC(O)C1CCCCC1)c1ccsc1 +Cc1ccc(C)c(NC(=O)CCC(=O)n2nc(C)cc2C)c1 +COc1cc(O)c2c(c1)C(c1cncc(C)c1)NCC2 +CC(=O)NC(C(=O)Nc1ccc(C(N)=O)cc1)C(C)C +CNC(=O)c1ccccc1C#CCNC(=O)NCCc1ccccc1 +CCc1onc(C)c1NC(=O)NCc1nccn1C(F)F +NC(=O)CCc1ccc(OCc2ccc(F)cc2)c(N)c1 +CC=CC1NCCc2cc(Br)cc(F)c21 +CC(=O)Nc1ccc(C(=O)OCC(=O)NC(C)c2ccccc2)cc1 +COc1cc(C#N)ccc1OCC(=O)Nc1ccc(F)cc1Cl +CCN(CC)C(=O)CSc1nncn1-c1ccc(C)cc1C +CC1OCCC1NC(=O)NCc1ccnc(OC(C)(C)C)c1 +CC(C)(C)NS(=O)(=O)c1ccc(N2CCCC2=O)cc1Cl +Cc1cccc(-c2nnc(SCCC(=O)N(C)C)o2)c1 +OC1(c2ccc(F)cc2)CCCCC1n1cncn1 +CN(C)c1ncncc1N1CCC(C(=O)N2CCCC2)CC1 +COc1ccccc1OCCNCc1cncnc1 +CCOC(=O)C(C)NC(=O)c1cc(Cl)ccc1F +N#Cc1ccnc(N2CCN(C(=O)c3nccnc3N)CC2)c1 +COCCC(=O)NC(C)C(O)c1ccc(OC)cc1 +COCC1CC2OCCN(C(=O)Cc3ccc(F)cc3)C2C1 +O=C(CCSc1nn2cnnc2o1)Nc1cccc(Cl)c1 +Cc1cnn(-c2ccc(S(=O)(=O)Nc3cn[nH]c3)cc2F)c1 +O=c1[nH]c(N2CCOCC2)nc2scc(-c3ccccc3)c12 +CNC(=O)c1ccccc1OC(=O)Cc1ccc(C)s1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2ccc(Cl)cc2)n1 +CS(=O)(=O)N1CCc2cc(C(=O)N3CCCC3)ccc21 +Cc1cc(OC(C)C(=O)n2ncc(C#N)c2N)ccc1C(C)C +N#Cc1nnn(Cc2cccc(F)c2)c1-c1ccco1 +CC1Cc2ccccc2N1C(=O)Cn1ccc(=O)[nH]c1=O +COCCCNc1nc(-c2ccccc2F)no1 +CN(C(=O)c1ccc(F)cc1)C(C#N)c1cccnc1 +O=C(NCc1ccccc1)c1cnc2ccccn2c1=O +O=C(Nc1ccc(Cl)cc1Cl)c1ccc(-n2ccnc2)nc1 +COC(=O)c1ccccc1C(=O)N1CCC(Oc2cnccn2)CC1 +CC(C)COC(=O)c1ccn(-c2ccccc2F)n1 +O=S(=O)(NCC(O)(c1ccccc1)C1CC1)C1CC1 +CNC(=O)C1CCCN(C(=O)CCCc2cc(F)ccc2F)C1 +CC(C#N)Sc1ccc(C(=O)N2CCCC2)cn1 +Cc1noc(C)c1C(C#N)Cc1ccc(Cl)cc1 +Cc1ccccc1CC(=O)Nc1cc(-c2cccs2)n[nH]1 +O=C(Cn1c(=O)oc2ccccc21)NCc1cccnc1-n1ccnc1 +CN1C(=O)CC(C(=O)Nc2nccs2)C1c1ccc(F)cc1 +COc1ccc(C(=O)NCc2ccc(OC3CCCCC3)cc2)nn1 +COc1ccc(OC)c(CN(C)C(=O)c2ccc(C(N)=O)cc2)c1 +COc1ccc(C2CCC(=O)C2)c(Cl)c1Cl +O=C(NC1CCCc2[nH]c(=O)ccc21)c1ccn(-c2ccccc2)n1 +Nc1nc2n(c1C(=O)c1ccc3c(c1)CCCC3)CCC2 +O=C(CN1CCOCC1C1CC1)Nc1nc2ccc(F)cc2s1 +O=C(NCCc1ccc2c(c1)OCCO2)Nc1nnc(C2CC2)s1 +COc1ccc(CCNc2cc(C#N)ccn2)cc1 +COc1ccccc1-c1nc(NC(=O)c2cnc3n2CCCC3)n[nH]1 +CC1CN(C)CCN1C(=O)C1CCN(c2ccc(Cl)cn2)CC1 +Cc1cc(C)c(NC(=O)CNC(=O)c2cc(C(N)=O)cs2)c(C)c1 +Cc1n[nH]c2c(N3CCN(c4ccccc4)CC3)ncnc12 +N#Cc1cccnc1SCC(=O)Nc1ccc(Cl)cc1Cl +Cc1cnc(CNC(=O)c2oc(COc3ccccc3)cc2C)cn1 +COc1cccc(C(=O)N2CCOC(C(F)(F)F)C2)c1O +C=CCOc1c(CN2CCc3ncnc(OC)c3C2)c(C)nn1C +O=C(NCc1ccncc1)c1cn(Cc2ccccc2Cl)nn1 +COc1ccc(CCNC(=O)C2CCCN(S(C)(=O)=O)C2)cc1 +CCN(CC1CC1)C(=O)Nc1ccc(CC(=O)NC(C)C)cc1 +Cc1ccccc1Nc1nc(N)nc(CN(C)Cc2ccccc2)n1 +CC(C)(C)C(=O)N1CCC(c2nc(C3CCCC3)no2)C1 +CC(C)CC(=O)Nc1ccc(N2CCNC2=O)cc1 +CNC(=O)Nc1cccc(NC(=O)c2cccc(OCCOC)c2)c1 +CCc1cc(=O)[nH]c(SCC(=O)N(CC)c2ccccc2)n1 +CCOc1c(F)cccc1C(=O)NCc1cn(-c2ccccc2)nn1 +Cc1nn(CC(=O)NCC2CC2)c(=O)n1-c1ccc2c(c1)OCO2 +COc1ccccc1NC(=O)CNc1cc(F)ccc1F +CN(Cc1nccn1C(F)F)C(=O)C1CC1(Cl)Cl +Cc1ccccc1-n1ccnc1SCC(=O)NCC(C)(C)C(N)=O +COc1ccc(S(=O)(=O)N(C)CCc2ccncc2)c(C)c1F +Cc1ccc(NC(=O)c2cc(C(C)C)n(C)n2)cc1S(C)(=O)=O +Nc1ncnc2oc(-c3ccco3)c(-c3ccco3)c12 +CCOCCCNC(=O)c1nn(C)c2ccc(Cl)cc2c1=O +COc1ccc(NC(=O)CCSc2ccccc2F)cc1OC +COc1cccc(CN2CCN(c3noc(C(C)C)n3)CC2)c1F +COc1cccc(OC)c1C(=O)Nc1ccc(F)c(C(N)=O)c1 +OCc1nnn(-c2cccc3c(O)cccc23)c1C1CC1 +NC(=O)CCN(C(=O)COc1ccc(F)cc1)c1ccccc1 +CCc1nnc(CNc2cc3ccccc3cc2C(=O)OC)o1 +CCn1cnnc1CNC(=O)Nc1ccc(C(C)=O)c(C)c1 +CC(C)S(=O)(=O)N1CCc2nnc(-c3ccccn3)n2CC1 +N#Cc1ccc(CCC(=O)OCc2cccc(C(N)=O)c2)cc1 +CC(=O)Nc1ccc(C(F)(F)F)cc1NCc1nccn1C(F)F +CC1(NC(=O)OC(C)(C)C)CCN(C(=O)OCc2ccccc2)C1 +CC(=O)c1ccc(-c2cnn(CC(=O)Nc3cc(C)nn3C)c2)nc1 +O=C(NCCn1nc(-c2ccc(Cl)cc2)ccc1=O)c1ccco1 +CCn1c(=O)n(Cc2nc(C)cs2)c2ccccc21 +CC(CNC(=O)c1ccco1)NC(=O)c1ccco1 +CCC(=O)Nc1cccc(NC(=O)N(C)CCC(C)C)c1 +CCOC(=O)C1CCN(C(=O)c2ccc(C(=O)OC)cc2)CC1 +Nc1ccc(C(O)c2ccc(Cl)cc2)c(Cl)c1 +Cc1ccc(C(C)NC(=O)NCC(=O)NCC2CC2)cc1F +CCC(C)C(NC(=O)c1ccc2c(c1)OCCO2)C(=O)OC +Cc1cccc(CC(=O)NCc2cccc(NC(=O)NC3CC3)c2)c1 +O=C(NCC1CN2CCCCC2CO1)NC1CCc2c(O)cccc21 +O=C1CCN(C(=O)c2cc(F)c(F)c(F)c2)CCN1 +Cc1nnc(CCCOc2cccc3c2OC(C)(C)C3)o1 +Cc1cc(C)n(CC2CCCCN2C(=O)c2csc(C3CC3)n2)n1 +CCN(CCc1ccccc1)C(=O)Cc1ccc[nH]1 +Cc1nnc(NC(=O)CCn2cc(Cl)cn2)s1 +CC(=O)Nc1c(C)nn(COc2cccc(F)c2)c1C +O=C(COc1ncccn1)Nc1nc2ccccc2s1 +CCCNC(=O)CCNC(=O)C1CC(=O)N(C)C1c1cccnc1 +CCS(=O)(=O)N1CCc2cc(C(=O)Nc3ccccc3F)ccc21 +COc1ccc(CC(=O)NCc2nnnn2-c2ccc(C)cc2)cc1 +COc1ccccc1Oc1c(-c2ccc(O)cc2O)n[nH]c1C +CC(C)C(=O)N1CCN(C(=O)C2CC(=O)N(c3ccccc3)C2)CC1 +C#CCN1CCN(C(=O)NCc2ccc(-n3ccnc3)c(F)c2)CC1 +C#CCN1C(=O)C2(CCC(C)CC2)Nc2ccccc21 +COc1ccc(N(C)C(=O)c2occc2COc2ccccc2)cn1 +Cc1ccc(C(=O)NCCCn2nc(C)cc2C)c(C)c1 +OCCN1CCN(c2ncnc3sc4c(c23)CCCC4)CC1 +O=S(=O)(c1ccccc1)c1cc2cc(CO)ccc2[nH]1 +CC1CC(C)CN(C(=O)CCCc2nc(C(C)(C)C)no2)C1 +CC(C)OCCCNC(=O)c1cc(C2CC2)nc2ccccc12 +Cc1cc(OCC(=O)N2CCCN(C(N)=O)CC2)ccc1Cl +COc1cc(-c2cnn(CC(=O)Nc3cc(C)nn3C)c2)nc(N)n1 +CCc1onc(C)c1NC(=O)CCc1ccc(F)cc1 +CC(CN1CCOCC1)NC(=O)c1nn(C)cc1Br +CCc1cc(=O)[nH]c2cc(NC(=O)c3ccc(F)c(F)c3)ccc12 +CC1CCCCC1OCC(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +CCOC(=O)Cc1cc(Br)ccc1F +COc1ccc(CC2(c3ccccc3)NC(N)=NC2=O)cc1OC +CCc1nnc(-c2coc(S(=O)(=O)N(CC)CC)c2)o1 +N#CC(NC(=O)CCc1ccncc1)c1ccc(F)cc1F +O=C(Nc1ccccc1)N1CCN(C(=O)c2ccco2)CC1 +CCOC(=O)CN1C(=O)C(C)(C)Oc2cc(CO)ccc21 +Cc1ccc2c(CC(=O)N3CCN(C4CCCC4O)CC3)c[nH]c2c1 +O=C(CN1CCOCC1)Nc1nnc(-c2ccccc2Cl)s1 +O=C(Nc1cccc(Cl)c1)N1CCCN(C(=O)c2cc[nH]n2)CC1 +Cc1cccc(NC(=O)CNC(=O)CC(C)(C)C)n1 +CN(CCO)S(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +CN(C)C(=O)CC1C(=O)NCCN1Cc1c(F)cccc1Cl +COc1ccc(NC(=O)C(C)Sc2nnc(C3CC3)n2C)cc1 +Cc1ccc(NC(=O)c2cccc(N3CCCC3=O)c2)c(C)c1 +CC(C)CCN(C)C(=O)c1cc(F)c(F)cc1Cl +C=CCNC(=O)Cn1nc(C2CC2)c2cnn(-c3ccccc3)c2c1=O +CC(C)(C)c1cc2nc(CNC(=O)c3cccnc3)cc(O)n2n1 +O=C1CCN(Cc2cc(Cl)cc3c2OCOC3)CCN1 +C=CCNC(=O)CN1CCN(c2ccc(OC)cc2)C1=O +O=C(Nc1ccc(N2CCOCC2)nc1)C1(c2ccc(F)cc2)CC1 +CC(=O)N(C)c1ccc(NCC(=O)Nc2ccc(C)cc2C)cc1 +N#CC1CN(C(=O)NC2CCCN(Cc3ccccc3)C2=O)CCO1 +CC(C)(C)c1n[nH]c(C2CN(Cc3nnc(C4CCC4)o3)CCO2)n1 +Cc1nnnn1-c1ccccc1C(=O)Nc1n[nH]c2cccc(F)c12 +CC(NC(N)=O)C(=O)Nc1nnc(C(C)C)s1 +O=C(NCCc1ccccn1)c1cc(-c2cccs2)n[nH]1 +CNC(=O)CN1CCN(CCn2ccnc2)CC1 +CC(C)(C)C(=O)NCCC(=O)Nc1ccc(N2CCOCC2)nc1 +COc1cc2c(cc1CN1CCn3c(CO)nnc3C1)CCC2 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCn2c(nn(C)c2=O)C1 +CCN(Cc1ccccc1Cl)C(=O)c1ccc(N(C)C)cc1 +Cc1ccnc2nc(C(=O)OCc3noc(-c4ccco4)n3)nn12 +COc1ccc(C)cc1CCNC(=O)c1cccc(C#N)c1 +Cc1ccc(-n2nnnc2CNC(=O)Nc2ccccc2F)cc1 +CC(C)Oc1nccnc1N1CCCC(CNC(=O)C(C)(C)C)C1 +CCC(Oc1ccc(Cl)cc1)C(=O)Nc1cc(C)on1 +COc1cc(CNc2ccc(CC(=O)N(C)C)cc2)cc(OC)c1 +CCC1CCCCCN1S(=O)(=O)CCNS(=O)(=O)CC +NC(=O)Nc1ccc(CNC(=O)Cc2cn3ccsc3n2)cc1 +CC(C)c1cc(C(=O)N2CCCC2c2nc3ccccc3[nH]2)[nH]n1 +CC(C)CC(CO)NC(=O)COc1ccccc1 +Cc1cc(C)cc(OCCC(=O)Nc2c(C)nn(C)c2C)c1 +Cc1noc(C)c1C(=O)Nc1ccc(NCC2CCCO2)c(F)c1 +N#Cc1ccccc1CN1CCN(c2ccccc2)CC1 +Cc1ccc(C)c(S(=O)(=O)Nc2ccc(C(N)=O)cc2)c1 +CCC(C)n1nccc1NC(=O)C(C)Sc1ccc(OC)cc1 +CCn1cc(NC(=O)c2ccc(OCc3nnnn3CC)cc2)cn1 +CC(Sc1c(Cl)cccc1Cl)C(=O)N(C)CCC#N +Cc1n[nH]c(C)c1NC(=O)NCC1CC12CCc1ccccc12 +CN(CCc1ccccn1)C(=O)c1cc(C2CC2)[nH]n1 +Cc1ccc(=O)n(CCCC(=O)Nc2cccc(C#N)c2)c1 +Cc1cc(C(=O)Nc2cccc(N(C)C)c2C)n(C)n1 +Cc1ccc(-c2nc3ncccn3c2Nc2ccc3c(c2)OCCO3)o1 +CC(C)N1CC(C(=O)Nc2cnn(C(C)(C)C)c2)CC1=O +O=C(Cn1nc2n(c1=O)CCCCC2)N1CCCC1 +CCc1cc2c(=O)n(NC(=O)C3CCOCC3)cnc2s1 +Cc1nc2c3cc(Cl)ccc3n(Cc3cccnc3)c2s1 +Cc1nc(C(NC(=O)CCn2cccn2)c2ccc(Cl)cc2)no1 +CCC(C(=O)Nc1sc(C)c(C)c1C(N)=O)c1ccccc1 +CC(=O)Nc1ccc(C(F)(F)F)cc1OC(C)C +Cc1noc(C)c1CN(C)C(=O)C1CCC(=O)NC1 +Cc1ccc(C(=O)NCc2cc(-c3ccco3)on2)cc1C +CCOC(C)c1noc(Cn2ncnc2-c2ccccc2Cl)n1 +OC1(O)CC=C(c2ccccc2)C(O)(O)C1(O)O +Cc1cc(OCC(=O)Nc2ccc(F)cc2)nc(N2CCCCC2)n1 +Cc1[nH]c(SCC(=O)NC(C)C)nc1Cc1ccccc1 +Cc1nnc(NCCC(=O)N2CCCc3ccccc32)c(C#N)c1C +O=S(=O)(Nc1ccc2c(c1)OCO2)c1ccc2c(c1)CCC2 +N#Cc1cc2c(=O)n3ccccc3nc2n(-c2cccc(Cl)c2)c1=O +O=C1CC(C(=O)Nc2nc(Cc3ccccc3)cs2)CN1 +CCS(=O)(=O)c1noc(C(=O)NC(C)C)c1N +COC(=O)c1ccccc1NC(=O)CCNC(=O)c1ccco1 +COc1cc(NC(=O)NCc2cccs2)ccc1N1CCCC1=O +CCc1cc(CN(C)C(=O)c2ccc3sc(C)nc3c2)on1 +COc1ccccc1C(C#N)NC(=O)Cc1ccc[nH]1 +Cn1c2ccccc2c2nnc(SCCC(=O)NC(C)(C)C)nc21 +O=C(NC1CC1c1cccc(Cl)c1)N(CCO)C1CC1 +COCC(NC(=O)c1cc2cc(F)ccc2o1)C(N)=O +Cc1cc(C)c(C(=O)COC(=O)c2cnn3cccnc23)cc1C +COc1cccc(-c2nccn2CCc2cnc[nH]2)c1OC +CC(C)COC1CCN(C(=O)c2cc3ccccc3n2C)CC1 +CCC1CCCC(NC(=O)NCC(Cc2ccc(F)cc2)C(N)=O)C1 +Cc1cc(NCc2c(C)nn(Cc3ccccc3)c2C)n2ncnc2n1 +N#CCOc1cccc(CC(=O)NCc2ncccc2F)c1 +CN(Cc1cc(-c2cccs2)n[nH]1)C(=O)c1cnc(C2CC2)nc1 +O=C(Nc1cccc(CO)c1)c1ccc2[nH]nnc2c1 +O=C(CCCc1nc(-c2ccccc2)no1)N1CCOC2CCCC21 +NC(=O)C1CCN(C(=O)C2(c3ccc(F)cc3)CC2)CC1 +CN1C(=O)CC(C)(C)Oc2ccc(C(=O)C3CCC3)cc21 +COc1ccc2nc(NC(=O)COC(=O)c3ccccn3)sc2c1 +COc1ncccc1C(=O)NCC(C)(C)c1ccncc1 +CCOC(=O)Cc1ccccc1NC(=O)Cc1c[nH]c2ccccc12 +O=C(NCc1cscn1)N1CCN(c2ccccc2Cl)CC1 +Cc1nc(C)c(C(=O)OCc2nc(N)nc(N(C)C)n2)s1 +COc1ccnc(NC(=O)c2oc3ccc(OC)cc3c2C)c1 +CCCC1=C(C(=O)OC)C(C)=NC1C(=O)N(C)Cc1c(C)noc1C +COc1ccc(CN(C)C(=O)c2cc(C)no2)c2cccnc12 +c1csc(-c2ncc(CN3CCOC4(CCC4)C3)s2)c1 +CCOC(=O)CCC(C)NC(=O)c1n[nH]c2ccc(C)cc12 +Cc1ccc(N2CCC3C2CC(=O)N3c2ccsc2)nn1 +CCCCOC(=O)C1=C(C)Nc2nnnn2C1c1ccc(O)cc1 +O=C(c1cncs1)N1CCC(Cc2cncc3ccccc23)C1 +Cc1ccc(-c2cc(C(F)F)n3ncnc3n2)cc1C +COCC1CCCN(C(=O)c2ccc(CCC(C)(C)O)cc2)C1 +C=CCc1ccc(OCC(=O)N=c2[nH]nc3ccccn23)c(OC)c1 +C#CCN(Cc1ccco1)S(=O)(=O)c1ccc(C(=O)NC)cc1 +O=C(Nc1cccnc1)c1cc(-c2ccc3c(c2)OCO3)on1 +CC(NC(=O)CC1C=CCC1)c1ccc(-n2cncn2)cc1 +COCC(=O)Nc1cc(C(=O)OC)cc(C(=O)OC)c1 +Nc1ccc(C(=O)CCC(=O)NCc2ccccn2)cc1 +CN(C)C(=O)Nc1cc2ncc(C(F)(F)F)cc2s1 +C#CCN1CCN(C(=O)NCc2ccc(C(N)=O)cc2)CC1 +CN(Cc1ccc2nonc2c1)C(=O)c1ccon1 +CC(NC(=O)c1ccc(CCNS(C)(=O)=O)s1)C1CC1 +CC(C)c1nc(C2CCN(C(=O)Cc3ccc(F)cc3)CC2)no1 +Cc1ccn(C(C)CC(=O)Nc2ccc(Cl)cc2)n1 +CC(C(=O)N(CC(F)(F)F)c1cccc(Cl)c1)n1cncn1 +Cn1ccc(C2CCCCN2C(=O)c2cccc(-n3cccn3)c2)n1 +Cc1ccc(F)c(C(=O)N2CCC(C)(O)C(C)C2)c1F +COC(=O)CN(C)C(=O)c1ccc2c(c1)CCCN2 +O=C(Nc1cc(-c2ccccn2)no1)c1nccc2ccccc12 +CCCNC(=O)C(C)NS(=O)(=O)c1c(C)noc1C +COc1ccc2c(c1)CC(NC(=O)NCCc1ccco1)CO2 +COC(=O)C1=C(C)C(C(=O)CN(C)c2ccccc2)=NC1C +O=C(Cn1c(-c2cccs2)noc1=O)NCCCc1ccccc1 +CCNC(=O)c1ccc(NC(=O)NCC2(C)CCCC2)c(C)c1 +CC(=O)Nc1nc(C(=O)NCC(=O)Nc2cccc(F)c2)cs1 +CN(C)C(=O)CN(C)C(=O)c1ccn(-c2ccccc2)n1 +CSc1nc(N)c(C#N)c(Cc2ccccc2)c1C#N +C=CCn1c(SCC(=O)NC2(C#N)CCCC2)nc2ccccc21 +Cc1cc(S(=O)(=O)N(C)CC(C)(C)O)c(Cl)cc1F +CCOC(=O)C1CCOc2c(Br)cccc2C1=O +CCC(=O)N1CCc2nc3scc(C)c3c(=O)n2CC1 +CC(C)S(=O)(=O)c1ccc(C(O)c2cccs2)cc1 +CC(=O)Nc1ccc(S(=O)(=O)Nn2cnnc2)cc1 +Cc1cc2c(=O)n(CC(=O)c3ccccc3C)cnc2s1 +CC(C)Oc1ccc(CNC2=NCCO2)c2ccccc12 +Cc1nc(-c2ccc(N3CCOCC3)c(N)c2)cs1 +CNc1ccc(Cl)cc1C(=O)Nc1ncccc1C +Cc1nc2ncnn2c(C)c1CCC(=O)NCC1CC1c1ccccc1 +COc1c(O)ccc2c1C(C=Cc1ccco1)NCC2 +O=C(Cc1cccs1)NCc1nc2ccc(F)cc2[nH]1 +CC(=O)Nc1ccc(Oc2ccc(N)c(C)n2)cc1 +CC(O)CNS(=O)(=O)N1CCc2ccccc2C1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(Cl)c(Cl)c1 +O=C(NCCO)c1ccccc1SCc1cn2ccccc2n1 +C=C(C)CN(CC)C(=O)CN1CC(C)OCC1C +CCCCN(CC)C(=O)c1cc(C(C)C)nc2onc(C)c12 +CC1CCCCN1S(=O)(=O)c1ccc(N)cn1 +O=C(NCc1cc(Cl)ccn1)Nc1ccc2c(c1)CCC2 +COCCNC(=O)c1cc(-c2ccccn2)nc2ccccc12 +CC1COCC(C)N1Cc1nc(-c2ccsc2)no1 +CCN(CC(=O)NC(C)(C)C)S(=O)(=O)c1ccc(OC)cc1 +CCCCCNC(=O)C(N)c1cc(Cl)ccc1C +COc1ccc(NC(C)=O)cc1NC(=O)Cc1ccc(C)c(C)c1 +COc1ccc(-c2nnc3sc(-c4cnoc4C)nn23)cc1 +CCn1c(SCC(=O)c2ccccc2)nnc1-c1ccccn1 +CC(C)c1nc(CN(C)C(=O)CSc2ccccn2)no1 +Cc1ccc(NC(=O)CCCNC(=O)c2cccs2)c(Cl)c1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)COc1ccccc1O +CCCS(=O)(=O)c1ccccc1C(=O)NCC1CCCO1 +O=S1(=O)CCCN1Cc1cn(-c2ccc(F)c(Cl)c2)nn1 +COc1ccccc1C=Cc1nc(-c2ccc(=O)[nH]c2)no1 +Cc1ccc(C(=O)N2CCN(Cc3ccccc3Cl)CC2)s1 +CCc1nnc(COC(=O)c2cc3cnn(C(C)C)c3nc2C)o1 +Cc1ccc(C(C)(C)C)cc1S(=O)(=O)C(C)C(=O)NC1CC1 +O=C1CC(C(=O)N2CCCCc3ccccc32)c2ccccc2N1 +Cc1cc(C(=O)NCC(N)=O)c(C)n1Cc1ccccc1 +Cc1nc(SCC(=O)N(C2CCC(C)CC2)C2CC2)oc1C +Cn1nc(CNC(=O)c2cccc(C#N)c2)cc1-c1cccs1 +Cc1ccccc1N1CCN(C(=O)Cc2cn(C)c3ncccc23)CC1 +COC(=O)CNC(=O)NC12CC3CC(CC(C3)C1)C2 +CC(C)Nc1ccc(S(=O)(=O)NC2CC2)cn1 +Cc1cc(C(=O)NC(C)COCC(F)(F)F)[nH]n1 +CN(C)C(=O)Cn1cc(C(=O)Nc2ccc(N(C)C)nc2)nn1 +O=C(Nc1ccccc1OCC(F)F)c1ncn(-c2ccccc2)n1 +CC(=O)Nc1ccc(C)c(NCC(=O)NCc2ccc(Cl)cc2)c1 +COc1ccc(-c2c(C)noc2-c2ccc(O)cc2O)cc1OC +Cc1nc2ccccc2n1CCNC(=O)C(C)n1cnc2ccccc21 +O=C(NCc1ccco1)C1CC2OCCC2N(Cc2ccccc2)C1 +Cc1ncnc(C)c1C1NCCc2c(F)cc(F)cc21 +CCOCC(=O)N(CC(=O)N1CCCCC1)c1ccccc1 +Cc1ccc(C(C)(C)CN(C)Cc2c[nH]nc2C)cc1 +CC(=O)c1ccccc1-c1ccc2c(c1)OCCO2 +CCC(NS(=O)(=O)c1c(C)nn(C(F)F)c1C)c1ccccc1 +O=C(NCC(O)c1cc(F)ccc1F)c1ccc(F)c(F)c1 +COc1ccccc1NC(=O)CC(C#N)c1cccs1 +Cc1cccc(C)c1OCC(O)Cn1cnc2ccccc21 +Cc1ccc(C)n1C1CCN(C(=O)Cc2cn3ccsc3n2)CC1 +CCc1ccc(S(=O)(=O)N(CC2CCOC2)C2CC2)s1 +Cc1csc(CNC(=O)CCN2C(=O)COc3ccccc32)n1 +Cc1nccc(C2(C)CCN(c3cnccn3)CC2)n1 +CC(c1cccnc1)N1CCN(C(=O)COCc2ccccc2)CC1 +O=C(Nc1ccccn1)c1ccc(Cn2nnc3ccccc32)cc1 +Cc1nn(CCCNC(=O)c2ccncc2)c(C)c1Br +COC(=O)CCNC(=O)Cc1csc(-c2ccccc2Cl)n1 +Cc1cccc2[nH]c(CCC(=O)NC(CO)c3ccccc3)nc12 +Cc1ccc(CNC(=O)Cn2cnc3cc4c(cc32)OCCO4)cc1 +CC(c1ccncc1)N(C)C(=O)Cc1c(F)cccc1F +O=C(Nc1cccc(F)c1)C1C2CCC1CN(C(=O)CCO)C2 +Cc1nccn1-c1cc(CNC(=O)c2ccc3ccccc3n2)ccn1 +Cc1cc(Cl)ccc1-n1c(C)c(C)c(C#N)c1N +CCOc1ccc(OC(=O)Cc2cn3ccsc3n2)cc1 +Cc1ccc(Cl)cc1-c1cc(C#N)nn1CC(O)CO +O=C1CN(C(=O)CCCNC(=O)c2ccc(Cl)cc2)CCN1 +Cc1nc(C2(NS(=O)(=O)c3ccc(C)c(F)c3)CCCC2)no1 +O=C(Nc1nc2cc(F)c(F)cc2s1)c1ccccn1 +Cn1cnc(S(=O)(=O)NCC(=O)N(Cc2ccccc2)C2CC2)c1 +COCCN1CC2(CCC1=O)CCN(C(=O)C(C)n1cccn1)CC2 +O=C(NC1CC1)c1cc(-c2ccnn2C2CCCC2)n2ccccc12 +Cn1cc(CCC(=O)N2CCc3cc(F)ccc3C2)cn1 +CC(C)CNC(=O)CCC(=O)c1cc(F)ccc1F +O=C(NCCNC(=O)c1ccccc1)Nc1ccncc1 +O=C(Cc1ccccc1)N1CCN(C2CCCC2)CC1 +Cc1noc(CCCC(=O)NCc2ccc(S(C)(=O)=O)cc2)n1 +O=C(Cc1noc(C2(c3ccc(F)cc3)CCC2)n1)NC1CCCC1 +CC#CC1NCCc2cc(O)c(OC(F)F)cc21 +COc1ccc(CCC(=O)NCC(O)c2ccsc2)cc1 +Cc1ccc(NC(=O)NCc2cccs2)cc1N1CCCC1=O +COc1ccc(CC(=O)NCC#CCOc2cccnc2)cc1 +CC(C)CC(=O)N1CCCCC1c1ccnc2ncnn12 +CCC1CCCCN1C(=O)c1onc(S(C)(=O)=O)c1N +Cc1ccc(CNC(=O)C2CCN(c3cn[nH]c(=O)c3)CC2)cc1 +COc1ccc(N)cc1NC(=O)C(C)n1cncn1 +Cc1cc(C)c(CNC(=O)NCc2cc(=O)[nH]c3ccccc23)c(C)c1 +CCn1ncc(-c2cccc(OC)c2)c(CC#N)c1=O +O=C(NCc1nnc2n1CCC2)c1cc(C2CC2)on1 +O=C(COc1ccc2ccccc2c1)Nc1cc(C2CC2)n[nH]1 +COC(=O)c1ccc2ncc(NC(=O)Nc3ccccc3)c(=O)n2c1 +CNC(=O)CNC(=O)c1cc(NC(=O)C(C)C)n(-c2ccccc2)n1 +O=C(NCc1ccccn1)C1CCN(C(=O)c2ccc(F)cc2)CC1 +O=C(Cc1cn2ccsc2n1)NCCC(=O)N1CCCC1 +C#CCN1CCCCC1C(=O)NCc1cc(C(C)C)no1 +O=C(COC(=O)CCc1ccccc1)Nc1ccccc1 +COc1cc(F)ccc1-c1ccc(=O)n(CC(=O)NCCC(C)C)n1 +CCCCNC(=O)Nc1cc(C(C)(C)C)nn1C +Cc1cc(C)c(S(=O)(=O)n2ccnc2)c(C)c1Br +CC1Cc2nc(N)nn2CC1c1ccc2c(c1)CCCC2 +CN(Cc1ccc2c(c1)OCO2)C(=O)Cn1cccnc1=O +O=C(CCCc1ccc(Cl)cc1)NC1CCCCNC1=O +COc1ccc(CNC(=O)CNC(=O)c2ccc3ccccc3c2)cc1 +Cc1cc(N2CCC(C(=O)N3CCN(C)CC3)C2=O)ccc1Cl +c1cncc(CNc2ncnc3c2oc2ccccc23)c1 +Cn1cnc2cc(C(=O)N3CCC4(CC3)OCCCC4O)ccc21 +CC(C)CCC(=O)C(C#N)c1nnc2n1CCCCC2 +CCCC(C)(C)NC(=O)NCc1cn(-c2ccccc2)nn1 +CCC(CC)C(=O)NCc1cc(-c2ccncc2)n(C)n1 +COc1ccc(-c2cc(-c3nc(C)no3)ccn2)cc1C +CC(C)(CNC(=O)c1cc(C(N)=O)cs1)N1CCOCC1 +Cc1occc1COC(=O)c1cc(F)ccc1F +Cc1nn(-c2ccccc2)c2[nH]c(=O)cc(C(F)(F)C(F)(F)F)c12 +Cn1nc2c(cc1=O)CN(c1ccc(C#N)cn1)CC2 +Cc1ccc(C(=O)OCC(=O)NCc2ccccc2F)s1 +Cc1ccc(CNc2nc(C)nc(OCC(C)C)c2N)cc1 +Cc1cc(NC(=O)CNc2cccc(Br)c2C)n(C)n1 +CCOc1ccccc1NC(=O)CSc1nc(=O)[nH]c(C)c1C#N +CCCC(C)NC(=O)CSc1nc2ccccc2[nH]1 +COc1cc(C)c(C(=O)Nc2cc(C(C)C)n[nH]2)cc1OC +COc1cc(Br)c(C(=O)C(C)CC#N)cc1OC +CC(C1CC1)N(C1CC1)S(=O)(=O)c1cc(F)ccc1F +COCCCC(=O)N1CCCC(c2n[nH]c(-c3ccccc3)n2)C1 +Nc1cccc(OCc2nnc3ccccc3n2)c1 +Cc1ncsc1C(=O)N(Cc1ccco1)CC1CCCO1 +COc1cc2c(cc1C)C(=O)C(C1(O)C(=O)Nc3ccccc31)CC2 +CCOC(=O)C1CCCN(C(=O)Cn2cc(C#N)c3ccccc32)C1 +CC(C)(C)NC(=O)Cn1c(NCc2ccccc2)nc2ccccc21 +CC(c1ccco1)N(C)C(=O)c1ccc(CNC(N)=O)cc1 +CCC(=O)N1CCCN(C(=O)c2ccc3c(c2)nc(C)n3C)CC1 +N#Cc1ccc(CNC(=O)c2c[nH]nc2-c2cccc(Cl)c2)cc1 +CSc1ccc(OC(=O)c2cnc3ccccn3c2=O)cc1 +COc1ccc(-c2nc(Cc3noc(-c4cnns4)n3)co2)cc1 +Cc1cc(NC(=O)CCCC(=O)N(C)C)ccc1Oc1cccnc1 +Cc1sc2ncn(CCC(=O)NCc3cscn3)c(=O)c2c1C +Cc1nccc(CNC(=O)NCCCOc2ccccc2C)n1 +COCC(C)OC(=O)c1cc(-c2ccc(F)cc2)nc2onc(C)c12 +COc1ccc(C)cc1NC(=O)CNc1ccccc1-n1cccn1 +CCCc1cc(C(=O)NCC2COc3ccccc3C2)[nH]n1 +Cc1ccccc1CC(=O)Nc1ccc(S(N)(=O)=O)c(C)c1 +CCc1nc(C)sc1CNC(=O)c1nnc2nc(C)cc(C)n12 +CC(NC(=O)c1ccc(S(C)=O)cc1)c1ccncc1 +CCOCCNc1nc(-c2ccncc2)nc2c1cnn2C +Cn1c(=O)c2ccc(C(=O)Nc3ccccc3O)nc2n(C)c1=O +O=C(CC1NC(=O)c2ccccc2N=C1O)NC1Cc2ccccc2C1 +O=C(NCc1nnc2ccccn12)c1ccc(Br)cc1F +CN(CCOc1cccc2c1OCCO2)C1COc2ccccc2O1 +COC(=O)c1ccc2nc(-n3ncc(C#N)c3N)sc2c1 +CCOc1cc(C2NC(=O)NC(CC)=C2C(=O)OC)ccc1O +CCC(Oc1cccc(C)c1)c1[nH]nc(C)c1CO +CC(=O)Nc1ccc(SCC(=O)N(C)Cc2cccs2)cc1 +O=C(NCc1ccc(F)cc1)c1cc2ccccc2oc1=O +CCn1c(C)nnc1COc1ccc(NC(=O)c2cnn(C)c2)cc1 +CCNc1snnc1CSc1nc(N)cc(N)n1 +CC(C)OCc1cccc(NC(=O)NCc2cccc(C#N)c2)c1 +COc1ccc(C(C)Nc2ccc(C)c(C(N)=O)c2)c(OC)c1 +O=C(NC1CC1)C1CC12CCN(S(=O)(=O)c1cccs1)C2 +Cc1nc[nH]c1-c1nccn1CCc1c[nH]c(=O)[nH]c1=O +CCc1ccc(CN(C)C(=O)C2Cc3ccccc3C(=O)O2)cc1 +N#Cc1ccc(NC(=O)Cn2nc(C(F)(F)F)c3c2CCC3)cc1 +Cc1cn2nc(NCCNC(=O)c3ccccc3)sc2n1 +CC(=O)NC(CC(C)C)C(=O)N1CCN(c2ccccc2)C(=O)C1 +O=C(CN1CCn2c(nnc2C2CC2)C1)N1CCc2ccccc21 +CN(C)S(=O)(=O)N1CC(Oc2cccnc2)C2OCCCC21 +CCC(=O)N1CCCC(C(=O)N(CC(C)(C)C)CC(F)(F)F)C1 +Cc1ccc(S(=O)(=O)N2CCN(Cc3ccccc3)CC2)c(C)c1 +CC(C)COC1CCN(C(=O)c2scnc2C2CC2)C1 +CCC(CC)c1nnc(NC(=O)c2ccnc(OC3CCC3)c2)s1 +COc1cc(OC)c2c(CO)cn(CCC(C)C)c2c1 +Cc1cccc(N2CCN(C(=O)CCNC(=O)C3CC3C)CC2)c1C +CCN1CCN(C(=O)C(CC(C)C)N2Cc3ccccc3C2=O)CC1 +Cc1ccc(S(=O)(=O)c2c(N)nc[nH]c2=O)cc1 +CCc1ncc(C(=O)N2CCCC(COc3ccccc3C)C2)cn1 +Cc1cc(=O)[nH]c(-c2cccc(NC(=O)C3CCOC3)c2)n1 +CCC(C)C(NC(N)=O)C(=O)N1CCN(c2ccc(F)cc2)CC1 +CN1CC(=O)N2CCC(NC(=O)C3CCCC3)C2C1=O +CC1Oc2ccccc2OC1C(=O)Nc1ccn(C)n1 +CC1=CC(C)=NC(=O)C1CNC(=O)C1Oc2ccccc2OC1C +CCN(C(=O)C(C)NC(N)=O)c1ccc(F)cc1 +CCN(CCO)C(=O)c1ccc(Oc2ccc(C(C)=O)cc2)cc1 +Cc1ccc(CC(NC(=O)Nc2cc(C)nn2C)c2cccnc2)cc1 +Nc1cccnc1SCC(=O)NCC(F)(F)F +CCc1n[nH]c(SCC(=O)Nc2ccccc2C)n1 +O=C(CC1CCCC1)N1CC(c2nc(-c3ccccc3)no2)C1 +Cc1ccc(NC(=O)CCCNC(=O)c2ccco2)c(O)c1 +CC(C)c1nc(COc2cccc(-c3nnco3)c2)no1 +O=C(NC(Cc1ccsc1)c1nccs1)C1CCOCC1 +CCOc1cc(C)c(Cl)cc1S(=O)(=O)Nc1cccc(C)n1 +O=C1NCC2(CCCN(C(=O)CCn3cnc4ccccc43)CC2)O1 +Cc1n[nH]cc1CNC(=O)c1cccc2c1OCCO2 +CC(=O)Nc1ccc(NCc2ccc(C)c(C)c2)cc1 +COc1ccc(Nc2cnc3ccccc3n2)cc1NC(C)=O +Cc1ccc(C(=O)N(C)Cc2cc(C)on2)c(C)c1 +O=C(Cn1cc(NC(=O)c2cc(Cl)c[nH]2)cn1)NC1CCCC1 +COc1ccc(N)cc1CNC(=O)c1ccccc1C +O=C(CCC1CCCCC1)Nc1ccc(-n2ccnc2)nc1 +O=C(NCc1cccc(NC(=O)c2cccnc2)c1)c1ccc(F)cc1 +COc1ncccc1C(=O)Nc1nc(-c2cccnc2)cs1 +CC1CCCC(NC(=O)NCCS(=O)(=O)c2ccccc2)C1 +CCOc1ncccc1NC(=O)N1CCCCCC1 +Cc1ccc(OCC2NCCc3c(N)cc(F)cc32)cc1 +OC(COc1ccc(Cl)cc1)CSc1nnnn1C1CC1 +CNC(=O)c1ccc(CN(C2CC2)S(C)(=O)=O)cc1 +CCOC(=O)C1CCN(c2cnn(C)c(=O)c2Cl)CC1 +C#CCOC(=O)c1ccc(CNC(=O)C(C)(C)C)cc1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(-c2ccccc2)[nH]n1 +COC(=O)c1cc(COC(=O)c2cn3ccc(C)cc3n2)oc1C +Cc1cc(-c2nc(CC(=O)NC3CCCCC3)no2)c(C)o1 +CCN(CCC#N)C(=O)CSc1nnc(C(F)(F)F)n1N +CC(NS(=O)(=O)c1cccc(C#N)c1)c1ccncc1 +O=C(Nc1ccncc1)c1nnn(-c2ccc(C(F)(F)F)cc2)n1 +CC(=O)N1CCN(CC(=O)Nc2ccnn2C(C)C2CC2)CC1 +O=C(CCNC(=O)C1CCCC1)Nc1ccccn1 +Cc1cc(C)n(-c2ccc(F)cc2CN(C)Cc2ccon2)n1 +CCOC1CCCN(C(=O)c2sc3ccccc3c2COC)C1 +CCC(CO)NC(=O)Nc1cc(Cl)ccc1Cl +CCOC(=O)CNc1ccccc1C(=O)NC1CC1 +CCC(C)C(NC(=O)c1cc(C)n(Cc2cccs2)c1C)C(N)=O +CC(=O)N1CCN(CC(=O)NCc2ccc(F)cc2)CC1 +CCN(C)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +O=C(Cc1ccc2c(c1)OCC2)N1CCOC(c2ccccc2)C1 +O=C(NCc1ccccc1F)C1CCCN(c2cn[nH]c(=O)c2)C1 +COC(=O)C(Cc1ccc(O)cc1)c1ccccc1 +CCOC(=O)CNC(=O)c1cc2cn(C3CCCC3)cc2s1 +CN(CC(O)C(F)(F)F)C(=O)Nc1ccc(OC(C)(C)C)cc1 +CNc1snc(C)c1C(=O)NCc1ccccc1Cl +Cc1ccc(S(=O)(=O)N(C)C(C#N)C(C)C)s1 +Cc1nc2scc(-c3ccccc3)c2c(=O)n1N +Cc1cc(C(C#N)C(=O)c2cccc(Oc3ccccc3)c2)nc(C)n1 +CN(CC(=O)Nc1ccccc1Cl)C(=O)OC(C)(C)C +C#CCN1CCN(C(=O)CNc2ccccc2C(F)(F)F)CC1 +CCN(CC)C(=O)c1ccc(NC(=O)C2=NC=CC2)cc1 +COc1ccc(C)cc1CN(C)C(=O)c1ccccc1S(C)(=O)=O +CCOC1CCCN(C(=O)Nc2cnn(Cc3ccccc3)c2)C1 +COc1cccc(-c2nc(C(=O)NCc3ncn(C)n3)c(C)[nH]2)c1 +Cc1nnc(SCC(=O)N2CCC(C)CC2)n1N +O=c1c2nnn(-c3ccc(F)cc3)c2ncn1Cc1ccccc1F +CC(CC1CCCC1)C(=O)N(Cc1ccco1)CC1CCCO1 +O=C(CCCc1nc2ccccc2o1)NCc1ccc(F)cc1 +C=CCNC(=O)c1ccccc1NCc1ncc(C(C)(C)C)o1 +N#Cc1cn(-c2ccc(NC(=O)c3nccn4ccnc34)cc2)nc1N +Cc1nn(C)cc1-c1ccnc(N(C)Cc2ccsc2)n1 +NC(=O)COc1ccc(C(=O)NCCc2cccc(F)c2)cc1 +CCOC(=O)CN(C)C(=O)c1ccc(N)c(C)c1 +Cc1cc(C)n(CCCNC(=O)CCc2ccccc2Cl)n1 +Cn1c(COc2cc(Cl)ccc2C(N)=O)cc(=O)n(C)c1=O +Cc1nc2cc(-c3ccccc3)nn2c(C)c1CC(=O)NC(C)C +O=C(NCCc1ccco1)c1ccc(S(=O)(=O)C(F)F)cc1 +CC(=O)N1CCC(NC(=O)CCc2cccs2)CC1 +Cc1csc(C(C#N)C(=O)CSc2nnnn2C2CC2)n1 +COCc1cc(C)nc2sc3c(c12)NCN(C(C)(C)C)C3=O +COc1ccc(Cl)cc1C(=O)N1CCOCC1CO +c1nc2nc3c(c(Nc4ccc5c(c4)CCC5)n2n1)CCC3 +NC(=O)c1cncc(-c2ccc(Cl)c(F)c2)c1 +c1ccc(N2CCN(Cc3cnn(-c4ccccc4)c3)CC2)cc1 +CC(=O)Nc1ccc(Cl)c(C(=O)N(C)Cc2sccc2C)c1 +CC(C(=O)N(Cc1cccnc1)CC1CCCO1)c1cccs1 +O=C(NCCCOc1ccccc1)Nn1cnc2ccccc21 +CC(NC(N)=O)C(=O)NC(CCc1ccccc1)c1ccccc1 +CCOC(=O)C1CCCN(CC(=O)c2cc(C)n(CC)c2C)C1 +CC1CCN(Cc2ccc(C(N)=O)cc2)c2ccccc21 +CCc1nc2n(n1)C(CC(=O)Nc1ccc(C)cc1)C(=O)N2 +COC(=O)c1c(C)[nH]c(C(=O)N2CCc3ccc(F)cc32)c1C +CCN(CCNC(=O)c1ccc(C)nc1)C(=O)OC(C)(C)C +c1csc(-c2n[nH]c(CSc3ncc[nH]3)n2)c1 +CCC(OC)C(=O)NCCS(=O)(=O)c1ccc(Cl)cc1 +O=S(=O)(Cc1ccc(F)cc1)NCCC(O)c1ccccc1 +N#Cc1ccccc1CNC(=O)c1cccc(N)c1 +Cc1cnc(C(C)NC(=O)NCCCc2c(C)noc2C)s1 +O=C(CNC(=O)C1Cc2ccccc2C(=O)O1)c1cccs1 +CS(=O)(=O)c1ccccc1C(=O)NCCc1nc2ccccc2[nH]1 +CCn1cc(C(=O)Nc2cc(C)n[nH]2)c(=O)c2cc(Cl)ccc21 +O=C1CC(c2ccc(-n3ccnc3)cc2)c2c(nc3sccn23)CN1 +Cc1ccc(NC(=O)c2cnccn2)c(C)c1S(=O)(=O)NC1CC1 +O=C(c1ccc(-n2cccn2)cc1)N1CCOC(c2ccccc2)C1 +C=CCOC(C)C(=O)N=c1[nH]c2cc(Cl)ccc2n1C +CNC(=O)Cn1cc(-c2ccc(F)cc2C(F)(F)F)cn1 +COc1ccc2cc(C(=O)Nc3ccc(N(C)C)cn3)[nH]c2c1 +CC(C)CNC(=O)c1cc(OCC(=O)N(C)C)n(C)n1 +CCSc1nnc(SCC(=O)NCc2ccco2)s1 +Cc1cc(NC(=O)N2CCCC2C(=O)NCc2ccco2)on1 +CCCn1cc(-c2cc(-c3ccc(O)cc3)nc(N)c2C#N)c(C)n1 +O=C(NCc1ccco1)c1cccc(CNc2ccccc2F)c1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)C1CCOCC1 +Cc1cc(N2CCc3cnc(C)nc3C2)n2ncnc2n1 +CN(Cc1cnn(C)c1)C(=O)Nc1ccccc1OC(F)F +COc1ccccc1CNC(=O)c1cccc(Nc2ncccn2)c1 +Cc1oc(NC(=O)c2cc(N)ccn2)c(C#N)c1C +COCc1c(C(=O)N2CCCC(C(=O)c3ccccc3)C2)noc1C +O=C(COc1ccccc1)Cn1cnc2ccccc21 +COc1ccc(OCCNC(=O)NCc2cscn2)cc1 +Cc1nc(CC(C)C)c(NC(=O)N2CCCCC2c2nc[nH]n2)s1 +CNS(=O)(=O)c1ccc(CCC(=O)NCc2cccnc2)cc1 +CCc1nc(C2CCCN2C(=O)CCn2nc(C)cc2C)no1 +CCc1noc(Cn2cnc3cc(-c4ccccc4)sc3c2=O)n1 +CCCOC(=O)COc1ccc2c3c(c(=O)oc2c1)CCC3 +O=C(C1CCOC1)N1CC2CN(Cc3ccncc3)C(=O)C2C1 +Cc1nnc(-c2cccc(NCc3ccccc3-n3cccn3)c2)o1 +CC(C)c1ccc(OC(C(=O)N2CCNCC2)C(C)C)cc1 +O=C(CN1CCc2cc(Br)ccc21)NCC1CC1 +Cc1ccc(C(CC(=O)N2CCOCC2)c2ccccc2)c(O)c1C +CCNC(=O)Nc1cc(Cl)ccc1N1CCCC1 +CCCNC(=O)C(C)NC(=O)N(C)Cc1cscn1 +OCCn1c(-c2cccs2)nc2cc(F)c(F)cc21 +CCS(=O)(=O)NCCCNC(=O)c1ccc2ccccc2c1 +Cc1nc2n(n1)CCCC2NC(=O)NCCc1ccc2c(c1)CCO2 +Cc1cc(N2CC3CCC(C2)N(Cc2cscn2)C3=O)nc(N)n1 +O=C(c1ccc[nH]1)N1CCC(OCc2ccc(F)cc2)CC1 +O=C(NCc1cccc(F)c1)Nc1ccc(-n2cncn2)c(F)c1 +CC(=O)Nc1ccc(F)c(C(=O)NCc2ccc(OC(C)C)nc2)c1 +O=C(Cc1noc(CCOc2ccccc2Cl)n1)NC1CCCC1 +Cc1nn(Cc2ccc(C#N)cc2)c(=O)c2noc(C)c12 +CC(C)c1cc(C(=O)N2CCOCC2)nc(N2CCCCC2)n1 +N#Cc1ccc(OCc2nnnn2-c2ccccc2)cc1 +CN(C)C(=O)c1cc(Cl)ccc1NC(=O)c1ccco1 +CNC(=O)CNC(=O)c1ccc(N2CCCC2=O)cc1 +CCn1nc(-c2ccc(OC)cc2)cc1C(=O)NCc1ccco1 +COc1ccc2cc(C(=O)NCCCc3ccccn3)n(C)c2c1 +O=C(NCC(O)(c1cccs1)C1CC1)c1nc2ccccc2s1 +CC(C)CNC(=O)c1c2c(nn1C)-c1ccccc1SC2 +C#CCN(C(=O)c1ccc(-n2ccnn2)cc1)C1CCCC1 +O=C(c1cscn1)N1CCC(c2ccc3ccccc3c2)C(O)C1 +CC(Nc1ccc(C#N)cn1)c1ccc(F)c(Cl)c1 +CC(C)NC(=O)COC(=O)c1ccc2c(c1)C(=O)c1ccccc1-2 +CCOC(=O)CN(CC)S(=O)(=O)c1ccn(C)c1 +COc1c(Cl)cc(Cl)cc1C(=O)Nc1c[nH]c(=O)[nH]c1=O +COC(=O)C1(N(C)C(=O)c2ccc(F)nc2)CCCCC1 +Fc1ccc(-c2cc(CN3CCOCC3)on2)cc1 +O=C(c1ccnc(OC2CCC2)c1)N1CCCc2ccccc21 +CCOC(=O)CC(C)CNC(=O)Nc1ccc(F)cc1F +Cc1ccc2oc(C(=O)N(C)CCn3cccn3)cc2c1 +CCC(Oc1ccc(C)cc1)c1nc(N)nc(C)c1C(=O)N(C)C +Cc1cccc(C(=O)N2CCc3ncnc(C4CC4)c3CC2)n1 +Cc1cccc(-c2c(-c3cn4ccccc4n3)c(=O)n(C)c(=O)n2C)c1 +Cc1ccc(-c2cc(CN(C)C(=O)c3ccco3)no2)c(C)c1 +CCc1cccc(OCc2c(CO)nnn2CC#N)c1 +N#Cc1ccc(OCC(=O)OCC(=O)NC2CCCC2)cc1 +COc1cc(C)ccc1NS(=O)(=O)c1ccccc1OC +Cc1ccc(CN(C)C(=O)c2ccc(Cl)cc2)o1 +O=C(Nc1ccccc1Cl)C1CCCN1C(=O)Cc1ccccc1 +CC(C)c1cccc(C(C)C)c1NC(=O)c1ccc[nH]1 +Cc1ccn2cc(-c3ccc(Cl)cc3)nc2c1N +Cc1ccc(S(=O)(=O)CC(=O)Nc2nc(C)cc(C)n2)cc1 +O=c1[nH]nc(CCC(F)(F)F)n1Cc1ccc(Cl)cc1Cl +Cc1cc(CN(C)C(=O)c2cnn(-c3ccccc3F)c2C)no1 +COC(=O)c1sccc1NC(=O)c1cc2ccccc2n1C +O=C(Cc1ccccc1Br)Nc1ccc2c(c1)COC2 +CCOC(=O)C1=C(C)C(C(=O)C(C)Sc2nccn2C)=NC1C +Cc1c(C(=O)N2CCCC2)cnn1-c1ccc(C(F)(F)F)cn1 +COc1ccc(S(=O)(=O)N(C)CCO)cc1C +Nc1cc(N)nc(SCc2ccccc2Br)n1 +CCOC(=O)CNS(=O)(=O)c1ccc(C)cc1Br +COc1ccc(C(=O)N2CCN(c3nc(C)c(C)c(=O)[nH]3)CC2)cc1 +Cc1ccnc(Nc2nc(-c3sc(C)nc3C)cs2)c1 +COC(=O)c1cc2ccsc2n1CC(=O)NC1CC1 +COCCCC(=O)NCc1cc(-c2ccccc2)no1 +CC1CCC(C(=O)NCC2CN3CCCCC3CO2)CC1 +Cc1c(C(=O)Nc2ccc(F)cc2F)nnn1-c1ccc(Cl)cc1 +Cc1ccc2occ(CC(=O)Nc3c(C)cccc3C)c2c1 +CCCCN(C)C(=O)c1cc2c(nc1N)CCCCC2 +CCc1csc(C2CCCN(Cc3ccc(C(=O)N(C)C)[nH]3)C2)n1 +O=C(Cn1ccccc1=O)Nc1cc(Cl)ccc1-n1cccn1 +CCCN(C)c1ccc(C(=O)N(C)CC(=O)NC(C)(C)C)cc1 +COC(=O)CNC(=O)c1ccc(Oc2ccc(F)cc2)cc1 +CC(=O)N(CCC(=O)Nc1ccc(C(N)=O)cc1)Cc1ccccc1 +Cn1nc(-c2nccn2CCCn2ccnc2)c2c(Cl)cccc21 +COc1ccc(Cl)cc1C1Cn2nc(N)nc2CC1C +CC(=O)Nc1ccc(O)c(C(=O)N2CCOC(C)(C)C2)c1 +CCC(NC(=O)c1n[nH]c(N)n1)c1ccc(Br)cc1 +CCOC(=O)CN(CC)C(=O)c1cc2ccccc2[nH]1 +NC(=O)c1ccc(NC(=O)CCN2C(=O)COc3ccccc32)cc1 +O=C(Nc1cnc(N2CCCC2)nc1)c1ccccn1 +COc1ccc(CC(=O)Nn2c(C)ccc2C)cc1 +Cc1nc(C)c(CC(=O)Nc2nnc(CC(C)C)s2)s1 +CN(CCc1ccccn1)c1cccc(Cl)c1C#N +CCCC1CN(C(=O)c2cn(C)nc2C(C)(C)C)CCO1 +CCCn1c(C)nnc1SCCc1c(C)noc1C +Cc1n[nH]c(SCC(=O)N2CCCC2CCc2ccccc2)n1 +O=C(c1ccncc1)N1CCc2c(nc(-c3ccccc3)[nH]c2=O)C1 +COc1ccc(OC)c(CN(C)C(=O)c2occc2C)c1 +Cc1n[nH]c(C)c1NC(=O)c1cc(Cl)cc(Cl)c1 +CC(C)C(=O)NCCNC(=O)N1CCCC1C1CCCC1 +O=C(NCC1CCCO1)c1cn2c3c(cccc3c1=O)CC2 +COc1ccc(CC(=O)Nc2cc(C)nn2-c2ccccc2)cc1 +O=C(c1ccc(CSc2nncs2)cc1)N1CCCC1 +Cc1nn(C)c(N)c1C(=O)Nc1cccc(Cl)c1 +CCNC(=O)CSc1nc2cc(Cl)cc(Cl)c2[nH]1 +Cc1noc(C)c1NC(=O)c1cc(NC(=O)c2ccco2)n(C)n1 +Cn1c(SCC(=O)NC2CC2)nc2ccccc2c1=O +CC(OC(=O)c1cnc(C2CCCO2)s1)c1nc2ccccc2[nH]1 +Cc1cccc(CN2CCN(c3nc(C)cc(C)n3)CC2)c1 +Cc1csc(N2CCCN(C(=O)c3ccc4cc[nH]c4c3)CC2)n1 +c1ccc2cc(OCCSc3nnnn3C3CC3)ccc2c1 +Cc1cn2nc(NC3CCc4ccccc43)sc2n1 +CCCOc1ccc(NC(=O)c2ccc(F)cc2)c(N)c1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cccc(Cl)c3F)cc12 +CCNC(=O)NCC(O)c1ccc2c(c1)CCO2 +O=C(NCc1cccnc1OCC(F)(F)F)Nc1ccccc1F +Cc1ccc2c(c1)CCCN2C(=O)c1cnc2sccn2c1=O +Cc1cc(N)n(-c2ncnc3sc4c(c23)CCCC4)n1 +Cc1cc(Br)ccc1Cn1ncn(C)c1=O +COc1ccc(C(=O)NCc2ccc(OC)c(OC)c2)cc1 +COc1cc(C(=O)NCc2cccnc2)cc(Cl)c1OC(C)C +COCC(NC(=O)c1ccn(-c2ccccc2)n1)C(N)=O +N#Cc1cccc(Cn2c(=O)oc3cc(Cl)ccc32)c1 +O=C(NC1CC1)C1CCN(c2snc3ccccc23)CC1 +CCCCN(C)c1ccc(C(=O)N2CCOCC2C2CC2)cc1 +COCC1(C(=O)NCC2CC(=O)N(C3CCCC3)C2)CCC1 +CC(C)CCNC(=O)CSc1ccccc1N +CCOC1CCN(C(=O)c2nn(-c3ccccc3)nc2C)CC1 +Cc1ccc(C)c(-c2nc(NC(=O)c3ccncc3)sc2C)c1 +Cc1nc(NC(=O)C(C)Nc2ccc3c(c2)CC(=O)N3)sc1C +CCCc1nnc(NC(=O)c2ccnc(OC3CCC3)c2)s1 +CCOC(=O)c1cnn(-c2ccnc(SC)n2)c1C(F)(F)F +COc1cc(C#N)ccc1OC(=O)c1cc(=O)[nH]c2ccccc12 +COc1ccc(F)cc1NC(=O)N1CCCC(c2cn[nH]c2)C1 +COc1ccccc1NCC(=O)Nc1ccccc1F +Cc1ncc(C(C)NCCc2ccccc2C)s1 +COc1ccc(OCc2nc(C(=O)N3CCCNC(=O)C3)co2)cc1 +O=c1ccn(C2OC3(CO)COC2C3O)c(=O)[nH]1 +CC(=O)c1cc2c(cc1NC(=O)c1cccc(F)c1)OCO2 +CCN(Cc1ccccc1)C(=O)c1cc2c(cn1)OCC2 +CCCNc1ccc(C(=O)N(CCC)C(C)C)nn1 +Cc1occc1C(=O)NCC(=O)N1CC(C(N)=O)CCC1C +Cc1ccncc1NC(=O)NC(C)COc1ccc(F)cc1F +CN(Cc1cccs1)S(=O)(=O)c1ccccc1F +CCn1cc(C(=O)N2CCC(Oc3c(C)cccc3C)CC2)cn1 +COc1ccc(N)cc1NC(=O)c1scnc1C +COc1ccc(C)cc1CN(C)C(=O)c1ccc2[nH]cnc2c1 +CCOC(=O)c1ccc(-c2cccc(OC)n2)s1 +Cc1nc(C)n(C2CCCN(C(=O)c3ccc4c(c3)COC4)C2)n1 +O=C(Cc1cccc(O)c1)Nc1cc(-c2ccncc2)c[nH]c1=O +CC(CNC(=O)c1nnc2ccccc2n1)c1ccc(F)cc1 +Nc1cc(F)ccc1NC(=O)Cc1ccc(F)cc1 +Cc1csc(C2CCCN(C(=O)C(C)Cc3c(C)noc3C)C2)n1 +O=C1OC(c2ccc(O)cc2)Sc2ccccc21 +O=S(=O)(c1ccc(-n2ccnc2)cc1)N1CCCC1 +O=C(CN1CCN(c2nccs2)CC1)NCc1cccs1 +CCC(CC)n1ccc(C(=O)N2CCCCC2C2OCCO2)n1 +Cn1nccc1CCNC(=O)Nc1ccc(C(=O)NC(C)(C)C)cc1 +CC1(NC(=O)c2scnc2C2CC2)CCOC1 +CCOC(=O)c1cn[nH]c1-c1ccc(F)cc1F +CCCCC(=O)Nc1cccc(NC(=O)C(C)C)c1 +CC(C)(C)OC(=O)NC1CCNC1c1cccnn1 +COC(=O)Cn1c(=O)c2c(nc3n(C(C)C)c(C)c(C)n23)n(C)c1=O +Cc1cccc(-n2ccc(=O)c(C(=O)Nc3cccnc3)n2)c1 +COc1cccc2c1OC(C)C(=O)N(c1ccccc1SC)C2 +CN(c1ccccc1)C1CCN(C(=O)CCn2cncn2)CC1 +Cc1n[nH]cc1NC(=O)c1ccc(COC(C)C)cc1 +COc1ccc(C)cc1NC(=O)Cc1ccccc1N +CCC(C)C(NC(=O)N1CCCCCC1)C(=O)OC +COc1cc(C)c(C(=O)Nc2cc(C)nn2C)cc1OC +CCOc1ccc(C(=O)c2ccc(NC(C)=O)cc2)cc1 +O=C(c1ccccc1)N1CCc2cc(-c3ccno3)ccc21 +CSc1cccc(-c2nnc(NC(=O)c3ccc(C#N)cc3)o2)c1 +CC1Oc2cc(N)ccc2N(CC(=O)N2CCCC2)C1=O +CCOc1ccccc1NC(=O)N=c1[nH]nc2ccccn12 +CCCNS(=O)(=O)c1ccccc1NC1CCC1 +COC(=O)c1ccnc(NCc2ccccc2C#N)c1 +Nc1ccccc1N1CCN(Cc2ccc(F)cc2)CC1 +O=C(NCC1CCC1)Nc1cccn(Cc2ccc(F)cc2)c1=O +CC(C)(C)OC(=O)NCC(=O)N1CCOC(c2ccccc2F)C1 +Cc1cc(C)n(CCC(=O)N(C)C(C)c2ccon2)c(=O)n1 +Cc1ccc(-n2cc(CO)nn2)cc1Br +O=C(NCc1nc2ccccc2[nH]1)C1CN(S(=O)(=O)C2CC2)C1 +CCCC1CN(C(=O)C(C)(C)NS(C)(=O)=O)CCO1 +Cc1csc(CN2CC3COCC3(COCC(=O)N(C)C)C2)n1 +CN(C(=O)COc1cccc2c1OC(C)(C)C2)C1(C#N)CCC1 +CCc1nnc(NC(=O)c2ccnc(SCC(F)(F)F)c2)s1 +CCCCC(NC(=O)c1c(C)c(C)c(C)[nH]c1=O)C(N)=O +CC(COCC(F)(F)F)NS(=O)(=O)c1cn[nH]c1 +CNC(=O)c1cc(Br)cnc1N(C)C +O=C1CC(c2ccccc2Cl)c2cnn(-c3ccc(F)cc3)c2N1 +CS(=O)(=O)c1c(Cl)cccc1S(N)(=O)=O +Oc1ccc(-c2oncc2-c2ccccc2)c(O)c1 +O=C(Nc1ccccc1F)c1ccc2c(c1)CCC2 +N#Cc1cnc(NC(=O)C2(c3ccccc3)CCOCC2)s1 +Cc1cnn(CCC(=O)N(Cc2ccco2)Cc2ccc(C)s2)c1 +Cc1ccc(CC(=O)N2CCCC(c3noc(C(C)C)n3)C2)cn1 +COc1ccc(CNS(=O)(=O)N(C)C)cc1OC +COc1ccccc1CNS(=O)(=O)c1cccc2cnccc12 +CCC(C)NC(=O)CC1CSc2nc(C(C)C)cc(=O)n21 +Cc1occc1C(=O)NCc1ccc(-n2cccc2)cc1 +Cc1nc(CNC(=O)NCC2(c3ccc(F)cc3F)CC2)oc1C +CC(C)CCNC(=O)c1ccc(F)cc1-n1cnnn1 +Cn1nc(C(=O)N2CCCCC2)c(=O)c2ccccc21 +O=C(Nc1cnn(-c2ccccc2F)c1)c1cccnc1-n1cccn1 +CC(C)Cc1noc(C(C)NC(=O)c2cc(-c3ccccn3)n[nH]2)n1 +C#CCNc1cccc(OCc2cccc(C#N)c2)c1 +CCN1CC(C(=O)Nc2cccn(Cc3ccccc3)c2=O)CC1=O +CCC(C)(NC(=O)Nc1ccc(-n2cccn2)nc1)c1nccs1 +CCCCS(=O)(=O)NCC(=O)N1CC(C)Cc2ccccc21 +CCOc1ccccc1OCC(=O)Nc1ccc(C#N)cc1 +COc1ccc2oc(=O)c(C(=O)NCCCN3CCOCC3)cc2c1 +C=CCNC(=O)NCCc1c(Cl)cccc1Cl +COC(=O)c1cc(CNS(=O)(=O)c2ccc(C)c(C)c2)oc1C +NS(=O)(=O)c1ccc(CNCC(F)(F)F)cc1 +C#Cc1cccc(N(Cc2nc(C3CC3)no2)Cc2cccs2)c1 +CNC(=O)c1cccc(OC(=O)COc2ccccc2C)c1 +CCC(C)(C)c1ccc(OC(=O)C(C)NC(=O)c2ccoc2)cc1 +O=C(Cc1nc(Cc2ccc(F)cc2)n[nH]1)Nc1ccc(F)c(F)c1 +O=C(c1cccc(F)c1)N1CCN2CC(OCC3CC3)CC2C1 +Cc1cc(NC(=O)c2ccccn2)ccc1Oc1cccnc1 +CC(C)NC(=O)c1nc2cc(N(C)C)ccc2n1C +CNC(=O)C1CCN(S(C)(=O)=O)c2cc(Cl)ccc2O1 +CCNC(=O)NC1CCC(OC(=O)C(C)OC)CC1 +CCCOc1cccc(OCc2nnc(CC)n2C)c1 +O=C(CCCNC(=O)c1cnc2ccoc2c1)Nc1cccnc1 +CN(Cc1ccco1)C(=O)c1c[nH]c2ccccc12 +Cc1cccc(OCCCC(=O)Nc2cccc(C)n2)c1 +O=C(c1cc(COc2ccccc2)[nH]n1)N(Cc1cccnc1)C1CC1 +CCOc1ccnc(N2CCN(C(=O)Cc3csc(C)n3)CC2)n1 +CC(=O)N1CCc2ccc(S(=O)(=O)N3CCCCC3)cc2C1 +CCOCCNC(=O)Nc1ccc(SC)cc1 +CC(C)c1ccc(NC(=O)Nc2cnccn2)cc1 +O=C(Cc1cccc(O)c1)N1CCN(c2cccnc2)CC1 +CCN(Cc1ccco1)C(=O)NCc1cccc(F)c1 +O=C(CCc1ccsc1)OCC(=O)N1CCCCCC1 +CC(C)C(C)NC(=O)c1ccccc1SCC(=O)N1CCCC1 +Clc1cc(COc2cccc(-n3cnnn3)c2)cc2c1OCCO2 +COC(=O)c1ccc(N2CCCC2)c(NC(=O)Cc2cccs2)c1 +NC(C(=O)NCCOCCO)c1ccc(O)cc1 +Cc1cc(=O)[nH]c2cc(NC(=O)Cc3ccc(F)cc3)ccc12 +CCOc1ccc(NC(=O)c2cc(OC)cc(OC)c2)cc1 +C=CCn1c(SCCn2cccn2)nc2ccccc21 +CCOCc1ccccc1CNC(=O)Nc1ccc2c(c1)COC2 +N#Cc1cccc(C(=O)N2CCC3(CC2)OCCCO3)c1 +CC(C)C(=O)Nc1cccc(NC(=O)Cn2ccc(=O)[nH]c2=O)c1 +COc1ccc(C(O)CCC(=O)N2CCOCC2)cc1 +NC(=O)C(CO)Nc1cc(-c2ccc(F)cc2)nc2ccnn12 +C=CCNC(=O)CSc1nnc2c3cc(C)ccc3n(C)c2n1 +CCN(Cc1nc2c(oc3ccccc32)c(=O)[nH]1)c1ccccc1 +COCC(C)NC(=O)CNc1ccc(C(N)=O)cc1 +COCc1nc(N2CCCNC(=O)C2)c2cnn(C)c2n1 +Cc1cc(C)n(CCC(=O)NCc2c[nH]nc2C)n1 +CC1CC(=O)c2cnc(Nc3ccc(F)cc3)nc2C1 +Cc1cc(C)cc(NC(=O)C2CCCN(c3ncccn3)C2)c1 +CN(C)C(=O)CCNc1ccc(C#N)cc1C(F)(F)F +CCC(C)C(=O)NCc1cccnc1Oc1cccc(OC)c1 +COc1ccc(Oc2cc(CNC(=O)CC3C=CCC3)ccn2)cc1 +Cc1ccsc1CNC(=O)CSc1ccc(O)cc1 +CCN(C(=O)C(C)OCC(F)(F)F)c1ccc(F)cc1 +O=C(CC1CCCC1)N1CCN(CCS(=O)c2ccccc2)CC1 +O=C(NCc1ccccc1)C1CC(=O)N(Cc2ccccc2)C1 +CC(=O)Nc1ccc(C(=O)N(CC(F)(F)F)C2CCOCC2)cc1 +CC(Sc1nc2ncccn2n1)C(=O)N(C)C +CNC(=O)c1ccc(NC(=O)c2cc(CC(C)C)n[nH]2)cc1 +Cc1ncc(CN2CCCC(n3cccn3)C2)n1-c1ccccc1 +Cc1nc(-c2cccc(NCc3cccc4c3OCO4)c2)n[nH]1 +CNS(=O)(=O)c1cccc(C(=O)N(C)CCC(F)(F)F)c1 +CCN(C(=O)C1CCN(C(N)=O)CC1)C(C)c1cc2ccccc2o1 +CN(C)c1cc(C(=O)NCc2ccnc(OC3CCCC3)c2)ccn1 +CC(C)n1ccc(=O)nc1SCC1CCCCO1 +CCOC(=O)C1(C#N)C(C#N)(C(=O)OCC)C1(C)C1CC1 +CCN1CCC2(CCN(C(=O)c3ccoc3C)CC2)C1=O +Cc1ccc(-n2nc(C(=O)Nc3ccnc(C)c3)c3c2CCC3)cc1 +Cc1ccnc(NC(=O)CN2CCc3ccccc32)c1 +COc1cccc(NCC2C(=O)OC(C)(C)OC2=O)c1 +NC(=O)CCC1CCCN(C(=O)Cc2cccc(O)c2)C1 +COc1cc(CCC(=O)Nc2n[nH]c(C(C)C)n2)on1 +COCCNC(=O)C(C)Sc1nc2ccccc2n1C(F)F +CC(C)NC(=O)c1ccc(NC(=O)CNc2cccc(Cl)c2)cc1 +CCOC(=O)C1CCCN(C(=O)CSc2ccccn2)C1 +CCOC(=O)CC(C)N(C)c1ccc(Cl)cc1 +Cc1coc2cc3oc(=O)cc(C(F)(F)F)c3cc12 +O=C(Cc1cc2ccccc2[nH]c1=O)NCc1cscn1 +CC(C)c1nc(CC(=O)N(C)Cc2ccc3c(c2)OCO3)cs1 +O=C(CN1CCCS1(=O)=O)N1CCc2ccc(F)cc2C1 +Cc1ccc(C(=O)C(O)NC(=O)c2ccccc2O)cc1 +Cc1noc(C)c1CC(=O)NCC1(c2ccccc2)CCC1 +Cc1ccccc1C(=O)NCCn1nc(-c2ccccn2)cc1C1CC1 +COC(=O)Cc1ccc(Cl)cc1Br +Cn1ncc(NC(=O)c2noc3c2CC(C(C)(C)C)CC3)c1C(N)=O +Cc1ncsc1CN1CCOC(c2ccc(C(N)=O)cn2)C1 +CC(OCc1ccccc1)C(=O)NC(C)c1nc(C(C)(C)C)no1 +Cc1n[nH]c(C)c1S(=O)(=O)Nc1ccc(Oc2ccccc2)cc1 +CC(=O)NCCNC(=O)c1cc(-c2ccncc2)nc2ccccc12 +Cc1cnn(CCC(=O)NC2CCCc3ccccc32)c1 +NC(c1ccc(Cl)cc1)c1nc(-c2ccncc2)n[nH]1 +c1ccc2oc(N=C3NCN(CCCN4CCOCC4)CN3)nc2c1 +COc1ccc(S(=O)(=O)NC2CC(=O)c3sccc32)cc1 +COCC(C)NC(=O)COc1ncnc2ccccc12 +COc1ccc(-n2ccc(=O)c(C(=O)Nc3cc(C)ccc3C)n2)cc1 +CCOc1ccccc1-c1cnn(CC)c(=O)c1CC#N +Cc1cc(C)n(C(C)C(=O)Nc2ccc(Cl)cc2)n1 +CC(C)CNC(=O)c1cccc(NC(=O)c2cc3cccnn3n2)c1 +Cc1ccc(-c2n[nH]c(NC(=O)c3ccco3)n2)cc1 +COCC(=O)Nc1cccc(-c2nc3c(C)cccc3o2)c1 +CC(C)CC(C)OCCC(=O)Nc1ccc2c(c1)CCC(=O)N2 +CC(C)C(C)N(C(=O)COC1CCCCC1)C1CC1 +CCOC(=O)C1(N)CC1c1ccc(SC)cc1 +CC(NC(=O)NC(C)C1CC1)c1ccc(F)c(F)c1 +CCC(=O)Nc1cccc(NC(=O)N2CCCC(CC)C2)c1 +CC(C)C(=O)N1CC(C)(C)Oc2ccc(C(=O)C(C)N)cc21 +Cc1n[nH]c2ncc(NC(=O)c3cc4c(s3)CCCC4)cc12 +O=C(Nc1ccccc1N1CCOCC1)c1ccnc2ccccc12 +O=C(Cc1cccc(F)c1)Nc1cccc(Oc2cnccn2)c1 +COc1ccccc1CNCCc1ccc(S(N)(=O)=O)cc1 +CNC(=O)Cc1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1 +CC(=O)C(N)CN1CCN(C(=O)OC(C)(C)C)CC1 +O=C(NCCNC(=O)C1CCCC1)c1ccccc1Cl +O=C(NCc1cccc2c1OCO2)c1cc2ccccc2c(=O)[nH]1 +CC(C)c1ccccc1NC(=O)c1cc2cccnn2n1 +CCCOc1ccc(N2CC(C(=O)N3CCCCC3)CC2=O)cc1 +CCc1ccc(N(C)S(=O)(=O)N(C)C)cc1N +CC(C)(C)NC(=O)CSc1nc(-c2ccccc2)cc(=O)[nH]1 +CC(C)CCNC(=O)CSc1ccc(N)cn1 +CC(C)C(=O)N1CCN(Cc2cc(-c3ccco3)on2)CC1 +N#CCCn1c(CC(F)(F)F)nc2c1CCCC2 +Cc1ccc2[nH]nc(C(=O)Nc3ccc(CC#N)cc3)c2c1 +CC1CN(C(=O)c2ccc(NC(=O)c3ccco3)s2)CC(C)O1 +COc1ccc2cc(NC(=O)c3ccc(Cn4cccn4)o3)cnc2c1 +CCOC(C)C(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +O=C(Nc1ccc(O)c2ncccc12)c1cccs1 +COc1cccc(OC)c1C(=O)N1CCC(CO)CC1 +CCOc1ccc(C(=O)NCC(=O)NCc2nc(C)sc2C)cc1 +O=C(c1ccncc1)N1CCc2onc(CNc3ncccn3)c2C1 +Cc1cccc(C(=O)N2CCOC3C(Oc4ccccn4)CCC32)n1 +COc1ccc(O)c2c1C(C(=O)c1cccs1)NCC2 +Cc1nc2c3ccccc3nn2c(C)c1CCC(=O)NC1CC1 +CCN(CCO)C(=O)c1ccccc1OCc1ccc(Cl)cc1 +CC(C)c1ccc(C2C3=C(COC3=O)Nc3cc4c(cc32)OCO4)cc1 +Cc1nc(-c2cccc(CNC(=O)c3ccc(F)c(C)c3)c2)n[nH]1 +COC(=O)CC(c1cc(C)c(C)cc1OC)C1CC1 +Cc1ccc(C(C)NS(=O)(=O)c2cnn(C)c2)s1 +O=C(Nc1ccccc1F)C1Cc2ccccc2S1 +COc1ccc(NC(=O)Cn2c(=O)nc(N)c3cc(C)sc32)cc1 +CCCCC(NC(N)=O)C(=O)N(C)Cc1sccc1C +CCOC(=O)CCC(=O)c1cccc(Br)c1 +CC(C)NC(=O)C(NC(=O)N1CCn2c1nc1ccccc12)C(C)C +CC(C)(C)n1cc(C(=O)N2CCC(C(N)=O)CC2)c2cccnc21 +NS(=O)(=O)N1CCc2ccc(NC(=O)c3cccc(F)c3)cc21 +CC(C)(C)CC(C)(C)NC(=O)Cn1cnc2ccccc2c1=O +CC(NC(=O)CCn1cnc2ccccc21)c1cccnc1 +O=C(NCCc1ccccc1)c1ncoc1-c1ccco1 +CC(C)c1ccccc1NC(=O)Cn1cc(C(F)(F)F)ccc1=O +Cc1cc(OC(F)F)c(C(=O)N(Cc2cnn(C)c2)C(C)C)s1 +COc1ccccc1S(=O)(=O)N1CCn2c(nn(C)c2=O)C1 +Cc1ncsc1CCN(C)C(=O)CN1CCCCCC1=O +Cn1cc(C(=O)N2CCCC2)cc(NC(=O)CC(C)(C)C)c1=O +CCc1ccc(OC)c(S(=O)(=O)N(C)CCO)c1 +Cc1cn2c(=O)cc(COC(=O)c3cccs3)nc2s1 +CNC(=O)C1=C(C)NC(=O)NC1c1cccs1 +Cc1noc(C2CCCN(S(=O)(=O)c3c(C)nn(C)c3C)C2)n1 +CSc1cccc(NC(=O)Cn2nnc(-c3ccc(F)cc3)n2)c1 +Cc1ccn2cc(C(=O)Nc3ccc(-c4cnc(C)o4)cc3)nc2c1 +Cc1ccc(CNc2ncnc3c2cnn3-c2ccccn2)o1 +CC(=O)c1c(C)[nH]c(C(=O)C(C)Sc2nnc(C3CC3)n2C)c1C +NC(=O)c1ccc(NC(=O)c2nccc3c(N)ccc(F)c23)cc1 +CCCC1CN(Cc2ccc(OCC)c(OC)c2)CCO1 +O=C(NCCc1nc2ccccc2[nH]1)OCc1ccccc1 +Cc1cccc(CN(Cc2ccccc2)Cc2nccs2)n1 +COC(=O)N1CCC(NC(=O)c2occc2-c2ccccc2)CC1 +O=C(Nc1cnn(CC2CC2)c1)C1CC1c1ccccc1 +COc1ccccc1CN(C)C(=O)CNC(=O)c1cccc(F)c1 +COCCn1cc(NC(=O)c2cc3c(s2)CCC3)ccc1=O +CC(=O)Nc1nnc(SCC(=O)c2ccc3ccccc3c2)s1 +CCS(=O)(=O)N1CCC(C(=O)NCc2cnc(C)s2)CC1 +COc1ccc(C)cc1CN(C)S(=O)(=O)N1CCCC(C)C1 +O=C(OCc1ccccc1)N1CC(O)(C(F)(F)F)C1 +Cc1cnc(C(=O)OCC(=O)c2ccccc2F)cn1 +CCc1cccc(NC(=O)NCc2nncn2C2CC2)c1 +COc1ccc2c(c1O)CCNC2c1ccncc1Cl +O=C1c2cccnc2C(Nc2ccccc2)N1Cc1ccc(F)cc1 +CCSc1cc(C(=O)NCc2nc(C)cs2)ccn1 +CCS(=O)(=O)NCCNS(=O)(=O)c1ccc(Cl)cc1F +COc1ccc(NC(=O)N2CCN(c3ccccc3OC)CC2)cc1 +CCCCNC(=O)NCc1ccc(S(=O)(=O)N(C)C)s1 +CCCc1ccc2c(c1)C(C1CCCN1C(C)=O)NCC2 +O=C(NCc1ccc(-n2ccnc2)c(F)c1)c1ccc(O)c(Cl)c1 +CC(CO)NC(=O)c1ccccc1Br +O=C(NCCC(=O)N1CCCC1c1ccc[nH]1)c1ccsc1 +Cc1cnc(CN2CCn3c(nnc3C3CC3)C2)cn1 +Cc1onc(-c2ccccc2)c1C(=O)OCC1CC(=O)N(C2CC2)C1 +Cc1ccccc1OCCNC(=O)NCc1ccsc1 +Cc1nc(-c2ccc(CCNC(=O)c3n[nH]c(=O)[nH]3)cc2)cs1 +CCOc1ccc2nc(SCc3c(C)noc3C)[nH]c2c1 +CC(C)(C)N1CC(NC(=O)c2cccnc2OCC(F)F)CC1=O +COCCCSc1nnnn1-c1ccc(C)cc1 +O=C(CO)N1CCN(C(=O)c2cc3ccccc3oc2=O)CC1 +Cc1ccc(-n2nnnc2SCC(=O)c2cc(F)ccc2F)cc1 +COc1ccc(C(=O)N(C)C(C)c2ccc(F)c(F)c2)nn1 +COc1ccc(NC(=O)c2cccc(CC#N)c2)cc1OC +CCCNC(=O)CSc1nnc(-c2ccncc2)o1 +CC(=O)c1nnn(CC(=O)Nc2ccc(C)cc2C)c1C +O=C(NCc1ccccc1)c1[nH]cnc1C(=O)N1CCCC1 +CCn1nc(C(=O)Nc2nc3c(C)cc(C)cc3s2)cc1C +Cc1ccc2c(c1)C(=O)C(=O)N2CCC(=O)N(C)C +CC1CC(Sc2nnc3n2CCCCC3)C(=O)O1 +COC(=O)CC1Nc2cc(C)c(Cl)cc2NC1=O +COC(=O)N1CCN(Cc2noc(C(C)(C)C)n2)CC1 +O=C1CCOc2ccc(-c3nnc(CCO)o3)cc2N1 +CC(CNC(=O)Nc1nccs1)S(N)(=O)=O +Cc1cccc(C(=O)C(C#N)c2ccccn2)c1C +Cc1nccc(CNC(=O)c2c(C)noc2C(C)C)n1 +CC(COc1cccc(F)c1)OC(=O)c1ccco1 +Cc1nnc(SCC(=O)N(C)C2CCCCC2C)c(C#N)c1C +O=C(NCc1ccccn1)c1nc(-c2ccccc2)n2c1CCCCC2 +O=C(NCCc1ccccc1)c1ccc(N2CCOC2=O)cc1 +CCc1nc(CNc2cc(Br)ccc2C)no1 +OCc1sc(COc2ccccc2F)nc1C1CC1 +Cn1nnnc1SCC(=O)c1ccc2c(c1)NC(=O)CO2 +COc1ncccc1C(=O)Nc1ccc(Cl)c(F)c1 +CC1CN(C(=O)c2ccco2)CC12CCN(c1ccsc1)C2=O +CCCOc1ccccc1NC(=O)Cn1ccc(=O)[nH]c1=O +CC(C)c1ccccc1NC(=O)c1cc(N)cn1C +Cn1cc(C(=O)c2cc(F)ccc2O)cc(C#N)c1=O +O=c1[nH]c(-c2ccccc2)ncc1Oc1ccccc1 +O=c1cc(CSc2nnnn2-c2ccccc2)nc2ccccn12 +Cn1ccc(NC(=O)c2ccc(-n3ccnc3)cc2)n1 +NC(=O)C1CCCN(S(=O)(=O)c2c(F)cccc2F)C1 +Cc1ccc(C(=O)OCc2cnns2)cc1F +CC(=O)c1ccc(NC(=O)c2cc(F)ccc2F)cc1 +CC(=O)Nc1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +C=CCNc1nc(C2CCCO2)nc(OC)c1N +N#Cc1cc(NC(=O)c2ccc(-n3ccnc3)cc2)ccc1F +COc1ccc(NC(=O)C(C)NC(C)=O)cc1Cc1ccccc1 +O=C(c1n[nH]c(=O)c2ccccc12)N1CCC2(CCCCC2)CC1 +COc1ccccc1CNC(=O)NCCc1csc(C(C)C)n1 +COC(=O)CN(C(=O)c1csc(-c2cccs2)n1)C(C)C +O=C(Nc1nc2c(s1)CCC2)c1cscn1 +CCN(CC)C(=O)N1CCC(C(=O)NCCCOC)CC1 +N#CCCN1CCN(CC(=O)N2CCOCC2)CC1 +COc1cc(C(=O)Nc2ccc3[nH]ccc3c2)cc(OC)c1OC +CC(C)N(CC(N)=O)C(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +Cc1nn(CC(=O)NCc2ccccc2Cl)c(=O)c2ccccc12 +O=C(NCCO)C1CC1c1ccc(C(F)(F)F)cc1 +Cc1cccc(-n2ncc3c2ncn2nc(-c4cccnc4)nc32)c1 +CC1CN(C(=O)NCCOc2ccc3c(c2)OCO3)CC(C)O1 +CCCNC(=O)CN1CCN(c2ccc(OCC)cc2)C1=O +O=C(Nc1ccc(-n2ccnc2)nc1)Nc1c(F)cccc1F +CCC(=O)c1ccc(OCC(=O)Nc2ccc(C(N)=O)cc2)cc1 +CCc1ccc(OCC(=O)N2CCN(CCO)CC2)cc1 +Cn1cc(CCc2nc(C3CCCC3)nn2CC(F)(F)F)cn1 +Cc1ccc(C)c(S(=O)(=O)NC2(C#N)CCOCC2)c1 +CC(C)C(NC(=O)N1CCN(S(C)(=O)=O)CC1)c1ccccc1 +CN(C)C(=O)CN(C)C(=O)Cc1ccc(F)cc1F +CC(C)CCCNS(=O)(=O)c1ccc(=O)[nH]c1 +Cc1ccc2c(c1)c(=O)c(-c1nc(-c3cccc(F)c3)no1)cn2C +CCc1n[nH]c(SC(C)C(=O)Nc2cccc3ncccc23)n1 +COc1cccc(C(=O)N2CCOC3CCCCC32)c1O +COc1ccc(C(=O)COC(=O)c2ccc3c(c2)OCO3)c(OC)c1 +CN(C(=O)CCOc1ccccc1Br)C1(C#N)CCC1 +CC(NC(=O)c1cnccn1)c1c(Cl)ccc(F)c1Cl +Cc1nc(-c2cc(C(=O)Nc3nccn(C)c3=O)co2)cs1 +Cc1n[nH]c(C)c1NS(=O)(=O)C1=Cc2ccccc2CC1 +O=C(NCc1csc(C2CC2)n1)Nc1cnn(CC2CCCO2)c1 +O=C(CCc1nnc(-c2ccsc2)o1)OC1CCCC1 +CC(C)Oc1ccc(NS(=O)c2ccc(N)cc2)cc1 +O=C(Cn1cc(C(F)(F)F)cc(Cl)c1=O)NCc1ccco1 +CC(C)NC(=O)Nc1ccccc1C(=O)Nc1cccn(C)c1=O +Cc1nc(C(=O)Nc2cc(C(C)(C)C)ccc2O)cs1 +Cc1ccc(-c2cc(C(=O)NCCc3cccc(O)c3)on2)cc1 +CCNC(=O)CNC(=O)c1ccccc1S(=O)(=O)C(C)C +CNC(=O)c1ccc(OC)c(NC(=O)c2cc3ccccc3n2C)c1 +CC(C)(C)OC(=O)N1CCC(CCOc2nc3ncccc3[nH]2)CC1 +COC(=O)c1noc(C(=O)Nc2cccc(C)c2)c1N +N#Cc1ccc(C(=O)Nc2nnc(-c3ccccc3Cl)o2)cc1 +CCCC(=O)Nc1cccc(NC(=O)NCc2cccc(OC)c2)c1 +COc1ccc(NC(=O)COC(=O)Cn2cnc3ccccc32)cc1 +O=C(NCC(F)(F)F)N1CCCC(Cn2cncn2)C1 +CC(C)(C)C(=O)Nc1ccc(CC(=O)NC2CC2)cc1 +Cn1ccc2cc(C(=O)Nc3ccc(C(N)=O)cc3)ccc21 +CC(C)CC1(CNC(=O)c2ncoc2C2CCCO2)CCCC1 +COc1ncnc(N(C)C)c1NC(=O)C(C)c1ccc(C)o1 +CCc1onc(C)c1NC(=O)N1CCCC(N2CCCC2=O)C1 +CCN(Cc1cccs1)C(=O)Cc1c[nH]c2ccccc12 +N#Cc1ccc(CNS(=O)(=O)C2CCOCC2)cc1 +CCN(CC)C(=O)CCC(=O)Nc1nncs1 +CCOC(=O)C1CCN(S(=O)(=O)c2ccc(SC)cc2)CC1 +CSc1ccc(C)c(C(=O)Nc2ccnn2C(C)C)c1 +Cc1nc(C2CCCN(C(=O)Cc3cccnc3)C2)sc1C +O=C(NCCc1ccccc1)Nc1ccccc1CN1CCOCC1 +CC(=O)N1CCc2sccc2C1c1ccc(N)cc1 +Nc1ncnc(Nc2ccc(Oc3ccccc3)cc2)n1 +COC(=O)C(C)n1c(-c2ccc(F)cc2)ccc(C#N)c1=O +CN(CC1CC1)C(=O)c1ccn(COc2cccc(Cl)c2)n1 +CC(=O)NCCNC(=O)NC(C)c1ccc2c(c1)OCCO2 +COC(=O)C1c2ccsc2CCN1C(=O)C(C)C +O=C(Nc1cccc(OCc2cccc(F)c2)c1)c1cnns1 +CC1(C)C(=O)NCCN1C(=O)CCCSc1ccccc1 +Cc1c(C(=O)N2CCCC(C)C2)sc2ccc(F)cc12 +Cc1cc(NC(=O)NC2CCCN(S(C)(=O)=O)C2)no1 +Cc1nc(C(=O)Nc2ccc3c(c2)OCCCO3)cs1 +CCC(C)(NC(=O)c1cccc(NC(=O)C2CC2C)c1)C(=O)OC +Cn1cc(CC(=O)NCC#Cc2ccccc2F)c2ccccc21 +Cc1ccccc1-c1noc(CNC(=O)Nc2ccccc2)n1 +O=C(Nc1ccc(O)cc1)c1cccn2c(-c3ccc(F)cc3)nnc12 +O=C(CSc1ncccc1Cl)NCCOc1cccc(F)c1 +Cc1nc(-c2cccnc2)nc2c1CCC(=O)N2Cc1cccnc1 +O=C(Nc1cccc(F)c1)NC1CCN(c2ccccc2)C1=O +O=C(CC1C=CCC1)Nc1cccc(CN2CCCC2=O)c1 +O=C(CN1CCCC1=O)Nc1ccc(Br)cc1 +CC(COc1ccccc1)NC(=O)c1ccc(-c2ccco2)[nH]c1=O +CN(C(=O)COC(=O)c1ccc(F)cc1F)c1ccccc1 +COC(=O)CCSc1nnc(-c2c[nH]c3ccccc23)n1C1CC1 +CN(CC(=O)N1CCOCC1)C(=O)CCc1ccc(F)c(F)c1 +O=C(c1nccs1)C1CCN(C(=O)c2cnn3cccnc23)CC1 +COc1ccc(-c2nc(-c3cccc(N)c3)cc(=O)[nH]2)cc1 +COc1cc(C(=O)N2CCCCC2)ccc1OCc1cscn1 +CC(C(=O)Nc1ccc(Cl)cc1C(N)=O)c1cccs1 +CCS(=O)(=O)N(CCCO)c1ccc(C)c(C)c1 +Cc1nc(CN2CCN(C(=O)c3c(F)cccc3Cl)CC2)no1 +COC(CNS(=O)(=O)Cc1ccc(F)cc1)c1ccsc1 +CCn1ncc(S(=O)(=O)NCc2ccccc2OC)c1N +O=C(NCc1ccc(COCC(F)(F)F)cc1)C1CC2CCC1O2 +Cc1nc(NCCc2ccccc2)cc(C2CN(C)CCO2)n1 +CCCCOC(=O)Cn1cc(CO)c2cc(C)ccc21 +O=C(COc1cc(F)cc(F)c1)N1CCN(c2ccccc2)CC1 +CC(=O)Nc1cccc(NC2=Nc3cc(N)ccc3OC2)c1 +COC(=O)CCC(=O)N(C)c1cccc2ccccc12 +COc1ccc(F)cc1CNCCc1ccccc1 +CC(C)(C(=O)N1CCN(c2ncccn2)CC1)c1ccc(Cl)cc1 +CCc1nn(C)c(OC)c1CN1CCOCC1c1ccc(C)o1 +Cc1c(C(=O)N2CCN(Cc3cccnc3)CC2)cnn1C(C)(C)C +NC(=O)C1CCN(C(=O)NCc2ccnc(OCC(F)(F)F)c2)C1 +O=C(c1cnn(C(=O)Nc2ccccc2)c1)c1ccccc1O +Cc1ccc(C(C)NC(=O)CCCN2CCOC2=O)s1 +Cn1ncc(N2CC3CC4CC(C3)CC2C4)c(Cl)c1=O +COCCNC(=O)c1ccc(C)c(NC(=O)c2ccco2)c1 +O=C(CSc1ccncc1)NCc1ccccc1-c1ccsc1 +Cc1nn(C)c(C)c1CCC(=O)Oc1cccc(C(N)=O)c1 +CC(=O)NC(CC(=O)N1CCOC(C)C1)c1cccs1 +CC(C(=O)NCc1ccc(F)cc1)N1CCN(c2nccs2)CC1 +Cc1ccc(NC(=O)NCc2ncc[nH]2)cc1S(=O)(=O)N(C)C +CCC(=O)c1ccc(OCC(=O)NC(C)c2ccc(C)o2)cc1 +NC(=O)Nc1ccc(C(=O)NC(c2ccccc2)c2ccccn2)cc1 +OC(Cc1ccncc1)c1cccc2cnccc12 +CC1CCCCC1OCC(=O)Nc1ccc(F)cc1N +COc1ccc2nnc(C(=O)NCc3ccccn3)nc2c1 +CC(=O)NCCNCC(=O)c1ccc(Cl)c(Cl)c1 +COC(C)C(=O)N(Cc1nnc(-c2ccccc2Cl)o1)C(C)C +O=C(Nc1ccc(N2CCOC2=O)cc1)NC1CCCCC1 +Nc1cccc(S(=O)(=O)Nc2cccc3ncccc23)c1 +Cn1cnnc1SCC(=O)Nc1nc(C(C)(C)C)cs1 +NC(=O)COC(=O)c1cc(C2CC2)nc2ccc(Cl)cc12 +Cc1nc2ccccc2n1CC(C)C(=O)NC1(C)CCC1 +COc1ccc(NC(=O)Cn2ccnc2)cc1Cl +COC(=O)c1ccc(Cn2cc(-c3nnco3)ccc2=O)cc1 +CCCCCC(C)NC(=O)Nc1cc(S(C)(=O)=O)ccc1C +CN(C)C(=O)C1CCN(C(=O)c2ccc3ccccc3n2)CC1 +COC1CCC(c2cc(Cl)cc(Cl)c2)n2nc(N)nc21 +Cc1nnc(C(C)OC(=O)c2ccc(N3CCCCCC3)nc2)o1 +COCCN(Cc1cnc2c(C)cccn12)CC(F)F +COC(=O)c1c(F)c(F)cc(Br)c1F +Cc1cc(C)nc(SCCC(=O)Nc2ccc(F)cc2)n1 +CCOc1ccc(CC(=O)Nc2ccc3c(c2)N(C(C)=O)CC3)cc1 +Fc1ccc(-n2ncc3c2ncn2nc(-c4ccncc4)nc32)cc1 +CNc1ccc(C(=O)NCCc2ccccc2)cn1 +CCCNC(=O)c1ccc2ncnc(N3CCCC3)c2c1 +CCc1nn(C)c(OC)c1CN1CCN(Cc2c(C)noc2C)CC1 +Cn1cnc(-c2cccc(NC(=O)c3ccco3)c2)n1 +CC(=O)OCC1OC2OC(C)=NC2C(OC(C)=O)C1OC(C)=O +CCN(Cc1ccccc1)C(=O)c1cn2c(n1)COCC2 +Cc1csc(CNc2ccn(-c3ncccc3Cl)n2)n1 +CCn1cc(NC(=O)c2nnc3ccc(Cl)cc3n2)cn1 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)N1CCCC1 +COc1ccc(-c2cn3c4ccc(N)cc4nc3n2C)c(Cl)c1 +Cc1nc2c(c(NC3CC3)n1)CCN(S(C)(=O)=O)CC2 +COCCn1ccc(NCc2sccc2C)n1 +Cc1ccc(-c2nc(CNc3ccccc3S(C)(=O)=O)co2)cc1 +O=C(NCCc1ccccn1)c1c(-c2ccccc2)nn2ncccc12 +CCc1cnc(N2CC3CC(C(=O)NC4CCC4)C(C2)O3)nc1 +O=C(OCC(=O)N1CCCCCC1)c1cnc(C2CCCO2)s1 +CNC(=O)c1cccnc1NCC1CCN(CC(F)(F)F)C1 +O=C(Nc1ccc2c(c1)OCCO2)c1ccnc2ccccc12 +CCN(Cc1ccco1)S(=O)(=O)c1ccc2c(c1)CCO2 +COc1cc2c(cc1F)C(C(C)NC(C)=O)NCC2 +Cc1noc2ncc(C(=O)Nc3nc4c(s3)CCC4)cc12 +O=C(CS(=O)(=O)c1ccccc1)NCC(F)(F)F +CCn1c(SCc2cccc(OC)c2)nnc1-c1ccccn1 +CCOC(=O)C1CCCN(C(=O)Cn2ncccc2=O)C1 +CCc1nc(CN2CCC3(CCCO3)CCC2=O)cs1 +Cc1nnc(-n2nnc(CO)c2C2CCCO2)s1 +Cn1ccc(C(=O)Nc2ccc(-n3ncc4ccccc43)cc2)cc1=O +Cc1cccc(S(=O)(=O)CCCOc2cc(C)c(C)nn2)c1 +Cc1cc(C)nc(NC2CCCN(C(=O)C(C)C)C2)n1 +CC12CCC(C(=O)N(CCC#N)CCC#N)(CC1=O)C2(C)C +N#CCn1ccc(NC(=O)Cc2ccc(Cl)cc2)n1 +O=C(Nc1ccc(Cl)c(Cl)c1)NC1CCCC1O +CCN(CC)C(=O)CN(CC)c1cc(C)nc(C)n1 +Cc1ccc(S(=O)(=O)Cc2ccccc2Cl)cc1 +Cc1ccc(OCCC(=O)NC2CCC(O)CC2)cc1C +COC(=O)C1CCn2nc(-c3cccc(O)c3)nc2C1 +Cc1cccc(OCC(C)NC(=O)c2ccc(F)nc2)c1 +COc1ccccc1NC(=O)C(C)Sc1nc(N)cc(=O)[nH]1 +CC(C)(C)C(=O)Nc1ccc2c(c1)NC(=O)CS2 +CN(CCSc1nc(N)c(C#N)cc1C#N)c1ccccc1 +O=C(Nc1cc(F)cc(C(F)(F)F)c1)N1CCCC(CO)C1 +CC(NC(=O)NCc1cscn1)c1ccc(F)cc1Cl +CCN1C(=O)Cc2cc(NC(=O)Cc3ccc(OC)cc3)ccc21 +CS(=O)(=O)N1CCCN(c2nccc(-c3cccnc3)n2)CC1 +CC(C)C(=O)N(Cc1nccn1Cc1ccccc1)C(C)C +COc1cc(C)ccc1NC(=O)C(C)OCC(F)(F)F +COC(=O)C(C)NC(=O)c1cc(-c2cccc(Cl)c2)no1 +Cc1nnc(C2CC3OCCC3N(Cc3ccc(C)s3)C2)o1 +Cc1nc2ccc(Cl)cc2cc1C(=O)N1CCN(CC(C)O)CC1 +CCCc1nc2cc(Cl)c(Cl)cc2n1CCC#N +CC(=O)c1csc(NC(=O)CCCOc2ccccc2)n1 +Cc1ocnc1CNC(=O)Nc1ccccc1OCC(C)C +CCCNC(=O)CSc1ncc(-c2ccccc2)o1 +O=C(NCc1cccnc1)c1ccc(-n2ccnn2)cc1 +CC(=O)N1CCN(CCn2c(C)csc2=O)CC1 +O=C(NCCS(=O)(=O)c1ccccc1)C1CC=CC1 +CCOC(=O)CC(C)CNC(=O)c1ccnc(F)c1 +Cn1cc(C(=O)Nc2ccc(F)cc2OCC2CC2)ccc1=O +O=C(CC1(O)CCCCC1)N1CCN(Cc2ccco2)CC1 +CCn1cc(CN2CCN(C(C)C(=O)N3CCOCC3)CC2)cn1 +COc1cccc(CS(=O)(=O)Nc2ccnn2CC2CC2)c1 +Cc1cc(C)c(C(=O)N2CC(c3ccccc3C)CC2C)c(=O)[nH]1 +Fc1ccccc1-c1n[nH]cc1CN1CCOC(c2nccs2)C1 +Cc1sc2nc(-c3cnn(C)c3)[nH]c(=O)c2c1-c1ccccc1 +NC(=O)C1CCCN(c2ccc(C(=O)OCc3ccno3)cc2)C1 +Cc1ccn2c(=O)nc(SCC(=O)NC(C)C)nc2c1 +NC(=O)C1Cc2ccccc2CN1C(=O)Cc1c[nH]c2ccccc12 +Cn1nc(C(C)(C)C)cc1C(=O)N1CCC(Oc2ccccc2)CC1 +CC(C)(C)NC(=O)CS(=O)(=O)c1ncccc1Cl +N#Cc1cnn(C(=O)CCc2cc(F)ccc2F)c1N +O=C(Cc1cccnc1)N1CCC(c2nccnc2-n2ccnc2)CC1 +CCOc1ccc(-c2cc(C(C)(C)O)c(=O)n(C)n2)cc1 +CC(C)(C)NC(=O)CN1C(=O)COc2cc(Br)ccc21 +CN1CC(C(=O)Nc2ccccc2C(N)=O)CC1=O +CN(Cc1cscn1)S(=O)(=O)c1ccccc1F +O=C(Cn1ncc(Cl)c(Cl)c1=O)c1ccc2c(c1)OCO2 +Cc1csc(=O)n1CCSc1nnc(NC(C)C)s1 +CC(C)Oc1nnc(SCc2nnnn2C2CC2)s1 +Cc1nc2c(c(=O)[nH]1)CCN(C(=O)c1c[nH]c(=O)c(Cl)c1)C2 +COC(=O)C1=C(C)NC(=O)CC1C(=O)Nc1ccc(C(C)=O)cc1 +Cc1cc(=O)n(CC(=O)Nc2c(C)cccc2C)cn1 +CC1CCCN(C(=O)NCc2ccccc2CN2CCOCC2)CC1 +Cc1cccc(CN2CCOC(C3CCCO3)C2)c1 +C#CC(OC(=O)C1CCN(CC(F)(F)F)CC1)C1CC1 +Cc1cccc(S(=O)(=O)NCCNc2cc(C)nc3ncnn23)c1 +Cc1ccc(NC(=O)C(C)Sc2cn[nH]n2)cc1C +CCN(CC(C)C#N)C(=O)CNc1cccc(C(N)=O)c1C +CC1CN(C(=O)NC2CCCOc3ccccc32)CC(C)O1 +CCCN1Cc2cccc(C(=O)NCc3ccc(F)cc3)c2C1=O +CCN(C(=O)c1ccc(C(N)=O)nc1)c1ccccc1 +CC(=O)N1CCc2c(nc(-c3ccccn3)nc2NC(C)CO)C1 +COc1ccc(N(C)S(=O)(=O)c2ccc(F)c(Cl)c2)cn1 +COc1cccc(NC2CCN(C(=O)COCC3CC3)CC2)c1 +CCc1ccc(C(COC)NC(=O)Nc2ccc3c(c2)COC3)o1 +CC(C)CC1COCCN1C(=O)Nc1ccncc1 +CCn1c(SCC(=O)N2CCOCC2)nnc1-c1ccco1 +O=C(c1cccc(-n2cnnc2)n1)N1CCNC(c2ccccc2)C1 +Oc1cc(OC(F)(F)F)c2c(c1)C(c1ccoc1)NCC2 +CC(NC(=O)C1COc2ccccc21)C1(N2CCOCC2)CCCC1 +Cc1ccc(C(O)C(=O)NCc2ccccn2)cc1 +CCN1C(=O)Cc2cc(NC(=O)c3ccc(N(C)C)cc3)ccc21 +CCCCn1nccc1NC(=O)c1c(F)ccc(OCC)c1F +O=C(CCc1ccccc1OC(F)(F)F)N1CCCn2ncnc21 +CC(C)OCCC(=O)Nc1ccn(Cc2cccc3cccnc23)n1 +O=C(NCCNC(=O)c1cccs1)NCC1CCOC1 +CC1CN(S(=O)(=O)c2ccccc2F)C(C)CO1 +NC(=O)CCn1nc(-c2cc(F)cc(F)c2)c2c1CCNC2 +C#CCN(Cc1ccco1)S(=O)(=O)c1cc(C)sc1C +O=C(Nc1cccc2cccnc12)c1cnn2c1OCCC2 +Cc1ccc(NC(=O)COC(=O)Cc2c[nH]c3ccccc23)cc1F +CC1=C(C(=O)Nc2cc(-c3ncco3)ccc2C)CCCO1 +Cc1cc(C2CCCN(C(=O)Cn3ccccc3=O)C2)n[nH]1 +O=C(c1cc2ccccc2cn1)N1CCOC(C(F)(F)F)C1 +CC(C)(C)C(=O)N1CCN(C(=O)NCCCn2cccn2)CC1 +CCc1ccc(-n2nnc(CO)c2C(F)(F)F)cc1 +CCn1c(SCc2ccc(F)cc2Cl)nnc1-c1cnccn1 +Nc1ccc(Cl)cc1NC(=O)COc1ccc(F)cc1 +COC(=O)NCC(=O)Nc1ccc(S(C)(=O)=O)nc1 +N#Cc1ccc(OCc2nc(-c3ccncc3)no2)cc1 +CS(=O)(=O)NCC1CCCN(C(=O)c2cnccn2)C1 +Cc1nc[nH]c(=O)c1CCC(=O)Nc1nc(-c2cccnc2)cs1 +N#CC(c1cccc(Cl)c1Cl)N1CCC(=O)CC1 +CCc1nc2sc3c(=O)[nH]cnc3c2c2c1COC(C)(C)C2 +O=C(NCCc1cccnc1)C1COCC(=O)N1Cc1ccccc1 +c1csc(-c2ccc(NCc3csnn3)cc2)n1 +Cn1cnnc1SCC(=O)Nc1ccc2c(c1)OCO2 +COc1cc(F)c(C(C)NC(=O)c2ccc(C#N)cn2)cc1OC +COC(=O)c1ccc(Cn2ccc3ccc(OC)cc3c2=O)o1 +COc1cccc(C(=O)Nc2ccc(-c3nncn3C)cc2)c1F +Cc1cccnc1NC(=O)C1(C)Sc2ccccc2N(C)C1=O +COc1cc(CNC(=O)c2[nH]c3c(c2C)C(=O)CCC3)ccn1 +O=C(CCOc1ccccc1)NCc1cccc(N2CCOC2=O)c1 +COc1cccc(CCC(=O)N2CCC(CO)C2)c1 +O=C(CNC(=O)c1cc(F)cc(F)c1)NCc1ccco1 +CCOc1ccc(NC(=O)NC(C)C)cc1CO +CC(=O)Nc1ccc(NC(C)C(=O)NC(C)(C)C)cc1 +Cc1ccc(C(N)=O)c(OC(C)C(=O)NC2CC2)c1 +Cc1cccc(NC(=O)N2CCCC2C(=O)NC(C)C)c1 +CN(C)C(=O)c1nccc2c(N)cc(Br)cc12 +O=C(NCc1ccccc1Cn1cncn1)c1cc(Cl)ccc1F +CCCOc1ccc(C(=O)NC2CCSc3ccccc32)cc1 +Cn1cc(Br)cc(NC(=O)COc2ccccc2)c1=O +CCn1c(CN2CCC(n3nc(C)cc3C)CC2)nc2ccccc21 +C=CCNC(=O)CCNS(=O)(=O)c1ccc(C)c(C)c1 +O=C(c1conc1-c1ccc(Cl)cc1)N1CCN(CCO)CC1 +N#CCc1nc2cccnc2n1Cc1ccccc1F +COCCN(C)C(=O)Nc1ccn(-c2cccc(C(F)(F)F)c2)n1 +CCC(CC)C(=O)Nc1ccc2[nH]c(C(C)O)nc2c1 +CS(=O)c1ccc(NC(=O)c2cccc(-c3ccoc3)c2)cc1 +CCCCC1C(=O)N(C)CCN1C(=O)c1c(F)cccc1OC +Fc1c(F)c(F)c(C2COCCN2)c(F)c1F +CCOc1ccc(NC(=O)NCc2nnc3n2CCC3)c(C)c1 +CC(C)(Br)C1NCCc2c(O)cc(O)cc21 +CCCCn1cnc2c1c(=O)[nH]c(=O)n2CCCC +Cc1noc(C23CCOC2CCN(Cc2csc(C)n2)C3)n1 +N#Cc1ccccc1NC(=O)CSc1nc(N)c2ccsc2n1 +O=C(Nc1ccccc1N1CCOCC1)c1csnn1 +Cc1nnc(CSc2nnc(-c3ccccc3Cl)n2N)o1 +COCCn1c(SCc2nnc(C)o2)nc2ccccc21 +O=C(Nc1cccnc1)C1CCCN1c1nc2ccccc2o1 +CC1=NC(=O)C(CCC(=O)NC(C)c2cc3ccccc3o2)C(C)=N1 +COc1ccccc1C(NC(=O)CCc1cccnc1)c1ccccn1 +Cc1cc(C(=O)Nc2cccc(-c3ccc(=O)[nH]n3)c2)c(C)n1C1CC1 +CS(=O)(=O)Nc1nc2ccc(NC(=O)c3ccccn3)cc2s1 +CCn1nnnc1-c1cccc(C(=O)NCCOC)c1 +O=C(NCC#Cc1ccccc1)c1ccc(CN2CCCC2=O)cc1 +COCc1ccccc1NC(=O)CNC(=O)c1cccc(Cl)c1 +Cc1nc(-c2ccc(OC(=O)C(C)OCC3CCCO3)cc2)no1 +CCCOc1ccccc1-c1nc2cc(N)ccc2[nH]1 +CC(C)c1n[nH]c(C2CN(C(=O)C3Cc4ccccc4O3)CCO2)n1 +CCCc1nc2nc3c(cn2n1)C(=O)CC(c1ccc(F)cc1)C3 +COc1ccc(NC(=O)C2CSc3nccc(=O)n3C2)c(OC)c1 +COc1nc(C)cc(C)c1CNC(=O)CCC(=O)NC1CCCC1 +O=C(c1ccc[nH]1)N1CC2OCCN(Cc3ccccc3)C2C1 +O=C(CC1CCCO1)Nc1ccc(-c2csnn2)cc1 +CCCNC(=O)CNC(=O)C(OC)c1ccccc1 +COc1ccc(-c2ccc3c(=O)[nH]cnc3c2)cc1OC +CC(C)(C)C(=O)NCC(=O)OCC(=O)N1CCCC1 +O=C(CNc1cccc(Cl)c1-n1cccn1)NCC(F)(F)F +COC(=O)C(C)Nc1nc2cc(Br)ccc2[nH]1 +Cc1noc(CNc2nc3c([nH]2)c(=O)n(C)c(=O)n3C)n1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)CC1CCCC1 +Nc1ccc(-c2nc(CCNc3cccc(Cl)c3)n[nH]2)cc1 +Cc1ccc(C)c(C(O)CNC(=O)CCOc2ccccc2)c1 +Cc1cccc(Cn2cc(C(=O)Nc3nnc(C)s3)ccc2=O)c1 +Cc1cccc2c(=O)n(CC(=O)OCC(=O)N3CCCC3)cnc12 +CCOc1ccc(NC(=O)COC(=O)c2ccc(F)cc2F)cc1 +COCCS(=O)(=O)N(C)Cc1cc(N)ccc1Cl +CN(CC(=O)OCC(F)(F)F)C(=O)c1ccccc1 +NC(=O)c1ccsc1NC(=O)COC(=O)c1cccc(Cl)c1 +CCC(C)c1cc(C(=O)Nc2ccc(C(C)=O)c(C)c2)on1 +CCN(CC)C(C(=O)Nc1n[nH]c(C)n1)c1ccccc1 +CC(=O)N(Cc1c(F)cccc1F)C1CCCC1 +CCOC(=O)CSc1[nH]c(=O)c(-c2cccs2)cc1C#N +CC(=O)N1CCc2cccc(NC(=O)c3ccc(C(F)(F)F)cc3)c21 +CN(C)C(=O)c1cccc(CN2CCCC3(C2)OCCO3)c1 +Cc1nc(CCNC(=O)Cc2cn3ccccc3n2)cs1 +CNC(=O)c1ccc(NC(=O)c2sc(C)cc2OC)cc1 +COc1ccc(Cl)cc1NC(=O)C1(C)Oc2cccnc2NC1=O +CS(=O)(=O)Nc1cccc(C(=O)NC2CCCc3ccccc32)c1 +Cn1cc2c(NCC3CN4CCCCC4CO3)ncnc2n1 +CCC(=O)Nc1ccc(C(=O)Nc2ccc(C(=O)OC)cc2C)cc1 +COC(=O)c1n[nH]c(N)c1-c1ccc(Cl)c(Cl)c1 +CCCn1c(C)ccc(-c2nnc(NC(C)CC)s2)c1=O +Cn1c(SCC(=O)NCCC(C)(C)C)nnc1C1CC1 +CCN(Cc1ccoc1)C(=O)NC(C)Cc1c(C)noc1C +COc1ccc(CCc2nnc(SC)o2)cc1N +CC(NS(=O)(=O)c1cccc(-n2cnnn2)c1)C(N)=O +C=CCC1CC=CC(C)N1C(=O)c1cc(CCC)on1 +CC(C)c1nc(CN2CCN(c3ccc(C#N)cc3F)CC2)no1 +CCC(NC(=O)C1CCC(=O)N1)c1ccc(Br)cc1 +Cc1cccc(C(=O)N2CCCN(C(=O)COCC3CC3)CC2)c1 +CC(c1cccs1)N(C)C(=O)c1cn(CC(=O)N(C)C)nn1 +COc1cc(OC)c(NC(=O)Cc2cccs2)cc1Cl +Cc1ccccc1N1CCN(C(=O)c2cn3ccccc3n2)CC1 +CC(=O)N1CCN(C(=O)c2csc(-c3ccccc3)n2)CC1 +Cn1cc(-c2ccccc2Br)nc1C#N +CS(=O)(=O)NCCc1ccc(C(=O)Nc2cccc(F)c2)cc1 +CCOc1ccc(NC(=O)c2sccc2CC)cc1CO +Cc1ccc(SCCCNC(=O)Nc2nccs2)cc1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCCc1c[nH]c2ccccc12 +CCNc1c(CC)c(C)nc2cc(C3CCOCC3)nn12 +CN(C(=O)Cn1nnc(-c2ccc(C(N)=O)cc2)n1)C1CC1 +NC(=O)N1CCCC(C(=O)Oc2cccc(Br)c2)C1 +O=C(COc1ccccc1)NCc1ccc(F)cc1 +FC(F)(F)c1csc(Sc2nnnn2C2CCOCC2)n1 +Cc1oc(CNC(=O)C2CCCC2)nc1C(=O)N1CCC(C)CC1 +Cc1nc(N(C)C)sc1C(=O)Nc1ccc2c(c1)OCCO2 +C#CCNC(=O)C1CCN(c2nc(C)cc(OCC)n2)CC1 +CC(C)C1CN(CC(=O)N2CCCC2)c2ccccc2N1 +O=C(Nc1ccccc1Cl)c1cc2ccccc2oc1=O +Cc1ncc(CNC(=O)c2ccc(Cl)c(S(C)(=O)=O)c2)s1 +NC(=O)c1cncc(N2CC=C(c3ccc(O)cc3)CC2)n1 +COc1ccccc1C(=O)n1cnc(-c2ccccc2)n1 +Clc1cnccc1CN1CCCC(c2ccn[nH]2)C1 +Cc1cc(C(=O)N(C)C)c(C)n1Cc1ccc(F)cc1 +O=C(NCCC1=CCCCC1)Nn1cnc2ccccc21 +COc1cc(C(=O)NCCc2ccccn2)cc(OC)c1C +CC(=O)c1csc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)c1 +CCN(CCC(=O)OC)C(=O)c1cccc2[nH]ccc12 +O=C(c1scnc1C1CC1)N1CCc2c(F)cc(F)cc2C1 +C=CCn1c(=O)c2c(nc3oc(C(C)(C)C)cn32)n(C)c1=O +COCc1cccc(C(=O)Nc2cc(OC)ccn2)c1 +CC(C)(C)OC(=O)N1CCCC1CS(=O)c1ncccc1C#N +Nc1ccc(-c2n[nH]c(Cc3ccc(F)c(F)c3)n2)cc1 +CSc1ccc(NC(=O)COc2ccc(F)cc2)cc1 +C=C1C2(C(=O)Nc3cc(C)on3)CCC(C2)C1(C)C +Cc1ccc(SC(C)C(=O)Nc2ccncc2)cc1 +C=CCOc1ccc(CNc2ncn[nH]2)cc1OC +COc1ccc(-n2ccc(C(=O)NCCNc3ccccc3)n2)cc1 +Cc1cccc(C2CCCN2C(=O)CCS(=O)(=O)N(C)C)c1C +CCc1cc(C(=O)NCC(O)COC2CCCCC2)[nH]n1 +CCOC(=O)CNC(=O)CN1CCN(c2ccccc2F)C1=O +Cc1nc(C(=O)NC2CC(C)OC(C)C2)c(=O)[nH]c1C +Cc1cc2c(cc1S(=O)(=O)NC(C)(C)C)OCC(=O)N2 +O=C(NC1CCCN(Cc2ccccc2)C1=O)c1n[nH]c2c1CCC2 +COc1ccc(OC)c(-c2csc(N3CCC(C(N)=O)CC3)n2)c1 +CNC(=O)CN(C)S(=O)(=O)c1ccc(F)cc1C +CCNC(=O)c1cccc(NC(=O)c2ccc(CNC(C)=O)cc2)c1 +COc1ccc(NC(=O)c2ccc(C)o2)cc1OC +O=C(CC1C=CCC1)Nc1cncc(Cl)c1Cl +Cc1csc(N2CCN(C(=O)Nc3ccnn3C(C)C)CC2)n1 +CCCNC(=O)CNS(=O)(=O)c1ccc(C)cc1 +Cc1noc(C)c1COc1ccccc1C(=O)NCC(C)O +CCN(C(=O)CSc1nccn1C)C1=CCCCC1 +COc1cc(NC(=O)CC(C)C(N)=O)c(OC)cc1Cl +O=c1[nH]c(CNCC2CC2)nc2cc(Cl)ccc12 +O=C(NCc1nc2ncccc2[nH]1)OCc1ccccc1 +CC(NC(=O)c1ccccc1F)c1cccc(N)c1 +Cc1csc(NC(=O)CCn2sc3ccccc3c2=O)n1 +O=C(c1cccnc1)N1CCN(Cc2cccc(F)c2)CC1 +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)N(C)Cc1ccco1)O2 +CCCc1noc(CN2CCCC2c2nncn2CC(C)C)n1 +O=C1NCC2CN(Cc3cnc(C4CCCC4)s3)CCN2C1=O +COc1ccc(F)c(NC(=O)NCCCNC(=O)c2occc2C)c1 +COc1ccc(CC(=O)Nc2nnc(-c3cccc(OC)c3)o2)cc1 +O=C(NCC1CCCCO1)c1ccc(F)cc1Cl +CCc1ccccc1CNC(=O)N(C)Cc1nccn1C(F)F +Cc1cc(C(=O)Nc2ccc(-c3cn4cccc(C)c4n3)cc2)no1 +CC1(c2[nH]ncc2S(C)(=O)=O)CCCN(C(=O)c2ccccc2)C1 +CC(C)n1nnnc1-c1cccc(C(=O)NCc2ccccn2)c1 +COC1(C)CC(NC(=O)NC(C)c2cnn(C)c2)C1(C)C +Cc1cc[nH]c(=O)c1C(=O)OCCCn1ccccc1=O +COc1ccc(OC)c(C(O)CNc2c(C)cccc2C)c1 +O=C(CCc1nc2ccccc2[nH]1)N1CCN(C2CCCCC2)CC1 +Cc1nnc2sc(CCc3ccc(Cl)c(N)c3)nn12 +Cc1cc2ccccc2n1CC(=O)OCc1nc(-c2cccnc2)no1 +NC(=O)c1csc(C(=O)NCc2ccnc(OC3CCC3)c2)c1 +O=C(Cn1nnc(-c2cccs2)n1)Nc1cc(Cl)ccc1F +O=C(Nc1cccnc1)c1ccc(NC(=O)c2cc(C3CC3)on2)cc1 +COc1ccc(OC)c(C2N(c3ccccn3)C(=O)C3CCCN32)c1 +Cc1nn(-c2nnn(CC(N)=O)n2)c(C)c1Br +O=C(c1ccc2[nH]cnc2c1)N1CCC(Nc2ccc(F)cc2)CC1 +O=C(CC1CCC1)N1CCCC(CO)(CC2CC2)C1 +CCCCCC(C)NC(=O)Cn1cnc2sc3c(c2c1=O)CCC3 +CCN1CC(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)CC1=O +CC(Sc1ncccn1)C(=O)NCC1CCCCC1 +CC(=O)N1CCc2ccccc2C1CC(=O)N=c1[nH]nc2ccccn12 +CCCNC(=O)Cn1nc(CC)n2c(cc3ccsc32)c1=O +CC(C)c1cc(C(=O)N(C)CCc2cn[nH]c2)n(C)n1 +COc1ccccc1CC1CCN(C(=O)C2CC(=O)N(C)C2)CC1 +CCOc1ccc(OC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +Cc1ccc(CC(=O)N2CCN(C3CCNC3=O)CC2)cc1 +CCOc1ccc(C(=O)N(C)CC(=O)Nc2cccc(F)c2)cc1 +COC(C)c1ccc(-c2cc(C)nc(N3CCOCC3)n2)cc1 +CSc1ccccc1NC(=O)NCc1nncn1C1CC1 +CN(C)C(=O)COc1ccccc1CN1CCOC(C#N)C1 +Cc1cc(NC(=O)NC2CCN(C(=O)CC(C)C)CC2)ccc1F +c1csc(-c2n[nH]c(CSc3nnc(-c4ccncc4)o3)n2)c1 +CCCCN(C)C(=O)c1c(C)oc2ccc(OC)cc12 +Cc1cc(NC(=O)COc2ccc(F)cc2Br)no1 +Cc1cc(C(=O)NCC(O)c2ccc(F)cc2)c2c(C)nn(C)c2n1 +CC(C)CC(=O)Nc1ccccc1CN(C)C(=O)c1cccs1 +N#Cc1ccc2nc(N)n(-c3nc(-c4cccnc4)cs3)c2c1 +N#CC(NC1CC1)c1ccccc1OC(F)(F)F +COCC(C)NS(=O)(=O)c1ccc(N)cc1C#N +COCC(NC(=O)c1ccc(C)c(Br)c1)C(N)=O +OCC1(O)CCN(c2cc(N3CCOCC3)ncn2)CC1 +c1nc(NCCCN2CCOCC2)c2ccsc2n1 +COc1ccc(CCC(=O)Nc2ccccc2Cn2cncn2)cc1 +CCCCc1nc2cc3c(cc2n1CCCC#N)OCCO3 +CC(N)C(=O)OCCc1ccc2oc(=O)n(C)c2c1 +CS(=O)(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +CC(C)Cn1ncc(C(=O)Nc2ccc(C(N)=O)cc2F)c1C1CC1 +CCCc1[nH]nc(C(=O)N(CC)CC(=O)NC)c1N +O=C(NC(c1ccccn1)C1CCCC1)C1CC(=O)N(CC2CC2)C1 +COC(=O)C(NC(=O)Cc1c(F)cccc1Cl)C(C)C +COc1cccc(CC(=O)N2CCCCC2CCN2CCOCC2)c1 +O=C(Nc1cc(N2CCCC2)ncn1)c1ccc(F)cc1Cl +CCCCS(=O)(=O)N1CCC(C(=O)N2CCCC2(C)C)CC1 +CCOC(=O)CCNC(=O)NC1CC(=O)N(C2CCCCCC2)C1 +CCCc1n[nH]c(C2CN(C(C)c3cccnc3)CCO2)n1 +COC(=O)CCC(=O)N1CCCCC1Cc1ccccc1 +CCC(C)n1ncc(C(=O)N2CCOC(c3ccco3)C2)c1C1CC1 +Cc1nnc(NC(=O)Cn2nc(N3CCOCC3)ccc2=O)s1 +Cc1cccc(C(C)C)c1NC(=O)c1ccc(=O)n(C)c1 +Cc1cc(Br)cc(C)c1NC(=O)CC#N +O=C(Nc1cccc(CO)c1)c1cc2c(s1)CCCC2 +CC(C)NC(=O)N1CC2CCC1CN(C(=O)c1cccnc1)C2 +COCC(C)(NC(=O)c1ccc(Cl)cc1Cl)C(=O)OC +Cc1nccn1-c1ccc(NC(=O)c2ccc3ccccc3n2)cn1 +CN(Cc1nnc2n1CCC2)C(=O)c1ccnc(N(C)C)c1 +Cc1nn(C)c(C)c1C(=O)NC1(C(=O)NCc2ccco2)CCCC1 +Cc1ccncc1NC(=O)N(C)C(C)c1ccncc1 +Cc1csc(C2CCCCN2C(=O)CCC(C)C)n1 +Cc1ccsc1C(=O)OCC(=O)NCc1cccc(Cl)c1 +NC(=O)CC1CCCCN1C(=O)c1cc(F)cc(F)c1 +Cc1nn(C)c(C)c1CNC(=O)c1nn(C)c2ccc(F)cc2c1=O +Cc1cn2c(nc3c2c(=O)n(Cc2ccccc2)c(=O)n3C)o1 +COc1cc(NC(=O)CC(C)C)c(OC)cc1Cl +COC(=O)c1cccc(OCC(=O)N2CCCC2)c1 +Cc1noc(C)c1CC(C)C(=O)NCc1cccc(NC(C)C)c1 +CCC(C)C(=O)N1CCCC(c2nc(-c3cccs3)no2)C1 +CC(C)(C)NC(=O)COc1ccc(C2CC(=O)Nc3n[nH]cc32)cc1 +COc1ccc2c(c1)N(S(C)(=O)=O)CCC2=O +O=C(CNC1CC1)OCc1ccc2[nH]c(=O)oc2c1 +Cc1cc(C)c(CNC(=O)CCCOc2ccc(Cl)cc2)c(=O)[nH]1 +O=c1nc(SCc2cccnc2)c2c(n1CCCO)CCC2 +O=C(c1cc(C2CC2)nn1-c1ccccc1)N1CCCC1 +Cc1ccccc1COC1CCN(C(=O)c2cccc3cn[nH]c23)CC1 +COCCCN(C)C(=O)c1cc(S(N)(=O)=O)ccc1C +Cc1csc(SCC(=O)Nc2ccccc2O)n1 +Cc1sc(=O)n(CC(=O)Nc2cccc(-n3nnnc3C)c2)c1C +COc1ccccc1-c1noc(C(=O)Nc2ccccn2)c1N +CC(OC(=O)c1cccc(C(F)(F)F)c1)C(N)=O +C#CCNC(=O)CSc1nc2ccc(OCC)cc2[nH]1 +C=CCN1C(=O)CCCC12CCCN(C(=O)Cc1cccc(F)c1)C2 +Cc1cc(O)c2c(C)c(CC(=O)N3CCN(C)CC3)c(=O)oc2c1 +CC(NC(=O)NCC(=O)NC1CC1)c1ccc(-c2ccccc2)cc1 +CC(C)CNC(=O)Cn1ncc2c(N3CCOCC3)ncnc21 +Cc1ccccc1CC(=O)N1CCCC1c1nnc2n1CCCCC2 +CC(C)C(=O)Nc1ccc(NC(=O)c2ccco2)cn1 +COc1ncnc2c1Sc1ncnc(N(C)C)c1N2 +COc1ccccc1N1CCN(C(=O)C2CCCN2C(N)=O)CC1 +CNC(=O)Cc1ccc(NC(=O)NC(C)c2ccccc2Cl)cc1 +CCC(O)CN1CCN(C(=O)NCc2ccco2)CC1 +Nc1cc(-c2ccc(-c3ccccc3)cc2)nc(N)n1 +Cc1nc(CSc2ccc(C(=O)Nc3ccn(C)n3)cc2)cs1 +COc1cc(C(C)=O)ccc1OCC(=O)Oc1ccc(Cl)cc1C +CC(=O)N1CCCC1C(=O)NCC1(c2ccc(F)cc2)CCCCC1 +CC(=O)c1sc(COc2ccc(C)c(C)c2)nc1C +CN(CCc1ccncc1)C(=O)c1cc(N)ccn1 +CCCCN(CC)C(=O)c1cc(C)c(C)c(S(=O)(=O)NC)c1 +CC1CC(C)CN(C(=O)CSc2ccccc2F)C1 +Cc1ccc(S(=O)(=O)NCCNC(=O)C2CC2C)cc1 +Cc1cc(NC(=O)CCSc2nc(-c3cccnc3)n[nH]2)no1 +CCOC(=O)Cc1nnc2ccc(-c3nc(C)no3)cn12 +O=C(c1ccccc1)N1CCn2nnc(COCc3cccnc3)c2C1 +COc1ccc(C(C#N)NC(=O)c2cccs2)cc1 +COc1cc(C)c(Cl)c(C)c1-c1n[nH]c(C)c1N +COC(=O)c1cc2occc2n1Cc1cccc(OC)c1 +CCOC(=O)CN(C(=O)C(C)OC)c1ccc(F)cc1 +COc1cccc(NC(=O)CCC(=O)c2ccc(C)cc2)c1 +COC(=O)CCS(=O)(=O)N(C)c1cccc(N)c1 +CC1CCCN(C(=O)NCC(C)(C)N2CCOCC2)CC1 +CCc1nnsc1C(=O)NCC1(c2ccc(F)cc2)CCOCC1 +O=C(CSc1nncs1)NCc1cccc(Cl)c1 +Cc1onc(-c2ccccc2)c1C(=O)NCCCO +O=C(Cn1nnc(-c2ccccc2)n1)NCCC1=CCCCC1 +COc1ccc(-n2cc(CNC(=O)C(C)(C)CC(C)C)nn2)cc1 +CC1(C)C(NC(=O)COc2ccccc2C(F)(F)F)C2CCOC21 +CC(C)CCC(C)NC(=O)NC1CCC(O)CC1 +CC(C)CN(C)C(=O)Cc1cnn(-c2ccccc2)n1 +COC(=O)c1nnsc1-c1cccc(Br)c1 +CCC1Cn2c(C(=O)NC(C)C)cc3cccc(c32)O1 +COc1cccc(CC(=O)N(C)CC(=O)N2CCOCC2)c1 +CCOC(=O)c1c(N)nn(C(=O)C(C)C)c1-c1ccc(OC)cc1 +CCc1cc(NC(=O)C(OC)c2ccccc2)[nH]n1 +Cc1cc(CC(C)C)nc(NS(=O)(=O)c2ccc(N)cc2)n1 +N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)c2ccco2)CC1 +CC(Cn1cncn1)NC(=O)C(C)Sc1nc2ccccc2s1 +COc1ccc(-n2nc(CC(C)C)nc2CCc2nncn2C)cc1 +COC(=O)c1c(NC(=O)C2CC2C)c(C)nn1C +CC1CCCN(C(=O)C(C)n2nc(-c3ccccc3)ccc2=O)C1 +CS(=O)(=O)Nc1ccccc1NC(=O)C1CCCC1 +Cc1ncc(CNc2nc3cc(Br)ccc3s2)s1 +Cc1ncn2c1C(CCC(N)=O)Nc1cnccc1-2 +CC(C(=O)Nc1cccc(S(=O)(=O)N(C)C)c1)c1ccsc1 +Cc1occc1C(=O)Nc1ccc(C(=O)NCCc2ccccc2)cc1 +O=C(Nc1cccc(Cl)c1)NC1CCN(CC(F)(F)F)C1 +COc1ccc(F)cc1NC(=O)c1cc(C)oc1C +O=C(c1cc2cc(F)ccc2[nH]1)N(Cc1ccco1)CC1CCCO1 +CCOc1ccc(-c2cc(C(=O)OC)nc(=O)[nH]2)c(Cl)c1 +Cc1c(NC(=O)Cc2ccsc2)c(=O)n(-c2ccccc2)n1C +CCn1c(C2C(=O)Cn3c2nc(=O)c2ccccc23)nc2ccccc21 +O=C(CSc1nncc2ccccc12)Nc1cccc(O)c1 +O=C(NC(CO)Cc1ccccc1)C1CCCOC1 +Cc1cccc2c(CC(=O)Nc3ccc(C(N)=O)c(Cl)c3)c[nH]c12 +CCn1nc(C(=O)Nc2cc(NC(C)=O)ccc2OC)ccc1=O +CCN(C(=O)CC(NC(C)=O)c1ccc(Cl)cc1)C1CCC1 +C#CCN(CC1CC1)C(=O)c1coc(S(=O)(=O)NC)c1 +COc1cc(F)c(C(C)NC(=O)c2cc(C)on2)cc1OC +CC(C)c1nc2c(S(C)(=O)=O)cccc2n1C +CCc1ccccc1CNC(=O)N(C)CCCNC(C)=O +CC(NC(=O)N1CCC2(C1)OCCO2)c1ccc(F)c(F)c1 +COC(=O)C(CC(C)C)NC(=O)c1cnn2c(C)cc(C)nc12 +COC(=O)C1C(=O)CC(=O)CC1c1ccc(OC)cc1 +CC(C)n1ncc2cc(C(=O)Nc3ccccc3)c(N)nc21 +O=C(Nc1cccnc1)c1ccc2nccnc2c1 +CN(C)c1ccc(C(=O)NCCNC(=O)c2ccco2)cn1 +CC(=O)Nc1ccc(CNC(=O)C2Cc3ccc(C)cc3S2)cc1 +CCN(CC)C(=O)Nc1ccc(N2CCCC2=O)c(OC)c1 +Cc1ccn2c(C(=O)N(C)Cc3c(C)noc3C)c(C)nc2c1 +Cc1c(C(=O)NC2(c3ccccc3)CCCC2)cnn1-c1ccncc1 +O=C(NC1CCSc2ccc(F)cc21)C1CC=CC1 +Cc1cc(C)c2cc(-c3nc(CC(=O)NC4CCCC4)no3)[nH]c2c1 +COc1cc(-c2cc(-c3cc[nH]c3)nc(N)c2C#N)cc(Cl)c1O +Cc1cc(-c2nnc(NC(=O)c3ccc4ncsc4c3)o2)nn1C +CC(C)c1noc(OCCOc2ccc(Cl)cc2)n1 +COc1ccc(C(N)=O)c(OCC(=O)N2CCCC2)c1 +COc1cc2c(c(CN(C)C(C)CC#N)c1)OC(C)C2 +CCN(CC(F)(F)F)S(=O)(=O)c1cccc(N)c1C +Fc1cccc(-n2ncnc2-c2ccccc2N2CCOCC2)c1 +Cc1cc(N2CCC(Cc3cc(N(C)C)ncn3)C2)ncn1 +COc1ccc(NC(=O)c2c(OC)cccc2OC)cc1N +NC(=O)C1CCCN(C(=O)c2cc(Cl)cc(Cl)c2)C1 +Cc1nc(C)n(CCCNC(=O)Nc2cc(C(C)(C)C)nn2C)n1 +CCOC(=O)CC1CCCCN1C(=O)CCc1ccco1 +COc1cccc(C(=O)N(CC(=O)N(C)C)CC(F)(F)F)c1F +CC1(C)CC(=O)c2sc(N3CCCCC3)nc2C1 +CCC(C)C(C)NC(=O)NCc1ccccc1OC +Cc1nnc2ccc(N3CCC(C(=O)N4CCCCC4)CC3)nn12 +Cc1cc(NC(=O)COc2ccc(Cl)cc2)n(C(C)(C)C)n1 +CCC(=O)N1CCCc2cc(Cl)cc(Br)c21 +COC(=O)CN1CCc2onc(-c3cccc4ccccc34)c2C1 +CCc1ccc(-c2ccc(C#N)c(=O)n2CCO)cc1 +Cc1cccc(OCC(=O)Nc2ccc3c(c2)N(C)C(=O)C(C)O3)c1 +O=C(Nc1ccncc1)C1(c2ccc3c(c2)OCO3)CCCCC1 +c1cc2c(cc1-c1csc(N3CCCC3)n1)COC2 +CC(C)CC1(CNC(=O)C2Cc3cc(F)ccc3O2)CC1 +O=C(Nc1ccc(-n2cccn2)c(F)c1)c1cccc(F)c1 +CSc1ccc(CNC(=O)NCC2CC2C)cc1 +CC(C)c1nc2cccc(F)c2n1C(C)(C)CO +Cc1cccc(NC(=O)c2csc(-c3cnccn3)n2)n1 +CC(=O)NCCC(=O)N1CCN(c2ccc(C(F)(F)F)cn2)CC1 +CN(C)c1ccc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)cc1 +CS(=O)(=O)N1CCN(C(=O)CCc2c[nH]c3ccccc23)CC1 +COc1ccc(NC(=O)N(C)Cc2cnn(C)c2)cc1C +CCC1Oc2ccc(N)nc2N(CC(=O)OC)C1=O +COc1ccc(S(=O)(=O)N(C)c2ccccc2)cc1C(N)=O +CCN(CC1CCCO1)C(=O)c1c(F)cc(Br)cc1F +NC(=O)CCNS(=O)(=O)c1cc(N)cc(F)c1 +Cn1c(SCc2nc3ccccc3[nH]2)nnc1-c1cnccn1 +N#Cc1c(F)cccc1NCCNC(=O)C1CCC1 +COc1ccc(CC(=O)N2CC(C(N)=O)CCC2C)cc1F +COc1cccc(CCNC(=O)c2ccc(-c3ccco3)nc2C)n1 +O=C(NCc1ccc(OC(F)(F)F)cc1)c1cc2n(n1)CCCO2 +CCN(C(=O)c1cnc(Cc2ccccc2)s1)C1CC1 +CC(NC(=O)c1ccn(C)c(=O)c1)c1c(Cl)ccc(F)c1Cl +CN(CCC#N)C(=O)c1ccc(SC(F)F)cc1 +COc1cccc(OCC2C3CCC(C3)N2S(C)(=O)=O)c1 +Cc1nc2c3ccccc3nc(NCCCc3nccs3)n2n1 +O=C1C(N2CCN(Cc3cncs3)CC2)CCN1c1ccccc1 +Cc1sc2ncnc(Oc3cccc(-n4cnnn4)c3)c2c1C +CCCn1nc(-c2cccc(Cl)c2)cc(CC#N)c1=O +CC1c2cccn2CCN1C(=O)CCc1nc(-c2ccccc2)no1 +O=C(NC(CCCO)c1ccccc1)c1ccncc1F +Cc1cc(C)n(-c2ccc(C(=O)NCCS(N)(=O)=O)cc2F)n1 +CSc1ccc(OC(=O)Cc2ccc(N3CCCC3=O)cc2)cc1 +O=C(NCc1ccc(CN2CCCC2=O)cc1)NC1CCC(O)CC1 +CC(NC(=O)CN1CC(C(N)=O)Oc2ccccc21)C1CC1 +CC(C)(C)c1nnc(SCC(=O)N2CCc3ccccc3C2)n1N +Nc1ccc2oc(=O)n(CCOc3ccccc3F)c2c1 +Cc1ocnc1CNC(=O)Nc1c(F)cccc1F +CCc1cccc(C)c1N1CCCCS1(=O)=O +O=C(CN1CCCc2cc(F)ccc21)NCc1ccco1 +O=S(=O)(NCc1cccc(OCC(F)(F)F)c1)c1cccnc1 +Cc1nn(C)c2ncc(C(=O)N3CC(=O)Nc4ccccc43)cc12 +CCOC(=O)N1CCN(C(=O)CNc2ccc(C#N)cc2)CC1 +COc1ccc(CNc2cc(C(=O)N(C)c3ccccc3)ccn2)cn1 +Cc1noc(CNC(=O)c2cccc(OCC(F)F)n2)n1 +CCC(C)OC(=O)CSc1nnc(-c2ccncc2)n1N +Cc1ccc(CNC(=O)c2cc(C3CC3)n[nH]2)cc1 +COCc1cc(NC(=O)NC2CCCC(C(F)(F)F)C2)ncn1 +CCOc1ccc(NC(=O)N2CCc3cc(F)ccc3C2)cn1 +Cc1ccccc1CN(C)C(=O)Nc1ccncc1 +CCn1c(SCc2csc(C)n2)nc2cc(C(=O)OC)ccc21 +CC(C)(NC(=O)CCCn1ccc2cc(Cl)ccc21)C(N)=O +Nc1nc(SCC(=O)N2CCCC3CCCCC32)n[nH]1 +CN(C)C(=O)C1CCN(C(=O)CCCCCc2cccs2)CC1 +COC(=O)C(O)CNS(=O)(=O)c1ccc2c(c1)CCO2 +COc1cccc(NC(=O)N2CCN(CC(F)(F)C(F)F)CC2)c1 +O=C(NC1CC=CC1)c1cnc(C2CCCO2)s1 +CCCC(C)CC(=O)Nc1sc(C)c(C)c1C(N)=O +Cc1nn(-c2ccccc2)cc1CN1CCOC2(CCC2)C1 +COc1ncc(NC(=O)C(c2ccccc2)c2ccccc2)cn1 +COCc1nc2ncc3c(=O)n(-c4ccc(C)c(C)c4)ccc3n2n1 +COc1ccc2cc(CNc3ccc(C)c(C)c3)c(=O)[nH]c2c1 +Cn1c(-c2ccc(C(=O)N3CCOCC3)s2)nc2ccccc21 +CCOC(=O)c1c(C)[nH]c(-c2cccc(OCC)c2)c1N +CN(C)c1cccc(OCCN2CCNc3ccccc32)c1 +CN(C)C(=O)CNc1cc(Cl)c(Cl)cc1Cl +CCN(c1ccc(F)cc1)S(=O)(=O)c1ccc(C(N)=O)cc1 +Cc1c(F)cc(C(N)=O)cc1NC(=O)c1cn(C)nc1C(C)(C)C +COc1cn(-c2ccccc2)nc1C(=O)Nc1cc(C)n[nH]1 +Cc1nnc(SCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)n1C1CC1 +N#Cc1c(N)n(Cc2ccccc2)c(=O)c2cccnc12 +CN(C(=O)c1ccc2c(c1)CCC(=O)N2C)c1cc(F)ccc1F +CC1CCCN(S(=O)(=O)c2ccccc2C(F)(F)F)C1 +CCCCN(C(=O)c1cnn(-c2ccncc2)c1C)C(C)CC +CC(C)C(Sc1ccccn1)C(=O)NCc1cccnc1 +N#Cc1cccc(CN2CCC3OC(C(=O)N4CCOCC4)CC32)c1 +COc1ccccc1OCc1ccc(C(=O)n2ncc(C#N)c2N)o1 +CCNC(=O)C1CCCN(c2ncc(S(N)(=O)=O)s2)C1 +C=CCn1cc(CN2CCCC2c2nc(-c3ccccc3)no2)c(C)n1 +CCCCCC(=O)Nc1cc(C(=O)N(C)C)ccc1OC +CC(C)Cc1nnc(NC(=O)NC(C)Cc2ccc(O)cc2)s1 +CCOC(C)C(=O)N1CCN(C(=O)Nc2ccc(F)cc2)CC1 +CC(C)(C)NC(=O)COc1c(F)c(F)cc(F)c1F +O=C(Nc1ccnn1C1CCCCC1)c1cccc(-n2cnnn2)c1 +CCOc1ccc(CC(=O)N2CCN(c3nccn3C)CC2)cc1 +CC(C)(CNC(=O)Nc1cnn(Cc2ccccc2)c1)c1ccncc1 +C#CCCOC(=O)c1ccccc1NCc1cccnc1 +Cc1ccc(C)n1-c1c(C(=O)OCC#Cc2ccccc2)cnn1C +CC(=O)c1c[nH]c(C(=O)N2CCC(CO)CC2)c1 +c1cc(-n2nc(C3CCOCC3)nc2CC2CCC2)ccn1 +Cc1nc2ccc(NC(=O)NCc3cccc(F)c3)cc2o1 +COc1ncnc2c1CN(CCS(=O)(=O)c1ccccc1)CC2 +N#Cc1cccc(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)c1 +CC(C)n1ncc2cc(C(=O)Nc3ccnn3C3CCCC3)cnc21 +CCOc1c(Br)cc(C(=O)N(CC)CCO)cc1OC +C=CCn1c(C)cn2c3c(=O)n(C)c(=O)n(C)c3nc12 +CCCNC(=O)CN(C)C(=O)CNc1ccc(Br)cc1 +O=S(=O)(c1cccc(F)c1)N1CC(OCc2cccc(F)c2)C1 +CCn1cc(-c2nnc(SCC(=O)Nc3ccc(C)cc3)o2)cn1 +COc1cccc2c1N(C(=O)NC1CCCCNC1=O)CCC2 +C#CCN(Cc1ccc(F)cc1)Cc1cnc(-c2cccnc2)s1 +CN(CC(=O)Nc1cc(F)ccc1Cl)C(=O)c1cccs1 +CN(C)C(=O)c1ccc(CN2CCN(C)c3ccc(Cl)cc32)[nH]1 +Nc1ncnc(SCc2ccc3c(c2)OCCO3)n1 +CCC1(CC)Oc2ccc(N)cc2N(CCO)C1=O +Cc1ccccc1NC(=O)c1cc2cccnc2[nH]c1=O +CC(=O)OCC1C=CC(N2CN=C3C(=O)N=CN=C32)O1 +COc1ccccc1CN1CCC(N2CC(C)OC(C)C2)CC1 +OC(COCc1ccc2c(c1)OCO2)CN1CCCc2ccccc21 +COC(=O)C1=C(C)Nc2nnnn2C1c1cccc(Cl)c1F +Cc1cc(NC(=O)Cc2ccc(Br)cc2)no1 +CN(C)C(=O)CN(c1cccc(Cl)c1)S(C)(=O)=O +CCOc1ccc(NC(=O)COc2cccc(NC(C)=O)c2)cc1 +Cc1nc2c(N(C)Cc3cnn(-c4ccccc4C)c3)ncnc2o1 +NS(=O)(=O)c1cnc(C(F)(F)F)c(OC2CC2)c1 +CCOc1cc(C(=O)NC2(C(=O)OC)CCCCC2)ccc1OC +CN(C)C(=O)Cc1ccc(NC(=O)c2cccnc2)cc1 +CC(=O)N1CCC(C(=O)N2CCN(Cc3cccc(C)c3)CC2)CC1 +Cc1ncsc1CN(C)C1CCN(c2ccccc2F)C1=O +Cc1ccc2c(c1)OC(C)CN2C(=O)CCn1c(C)c(C)sc1=O +Cn1cnc(S(=O)(=O)NCC(=O)N2CCCC(C)(C)CC2)c1 +Cc1cc(C)c(NC(=O)CN2CCN(c3ccccc3)C2=O)c(C)c1 +CCc1noc2ncnc(NCc3ccc(Cl)cc3)c12 +CS(=O)(=O)Nc1ccc(OC(=O)c2ccco2)cc1 +CC(=O)c1ccc(NC(=O)c2cc(N)c[nH]c2=O)cc1 +O=C1N(c2ccccn2)CC2CN(C3CCOCC3)CCN12 +COc1ccc(OCC(=O)N2CC(OCc3cccc(F)c3)C2)cc1 +CC(C)NC(=O)NCCOc1ccc(F)cc1F +CCc1noc(CC)c1CC(=O)NCc1cn2cc(Cl)ccc2n1 +COc1ccc2c(c1)CN(C(=O)NCC(=O)NC(C)(C)C)CC2 +CCn1nc(C)c(-c2cc(C(=O)N=c3[nH]cc[nH]3)[nH]n2)c1C +COCCOc1ccc(NC(=O)c2ccc(F)cc2)cc1 +COc1ccccc1CNc1ccc(NC(=O)C2CCCO2)cc1 +COc1ccc(C(=O)COC(=O)c2ccco2)cc1OC +CCN1Cc2ccccc2CC1C(=O)NCc1cnc(C)cn1 +Cc1csc(=O)n1CCC(=O)Oc1ccccc1 +CCCCCN1C(=O)C(CC)N(C)c2ccc(N)cc21 +O=C(c1cccnc1)N1CCN(C(=O)c2cc(F)cc(F)c2)CC1 +CC(C)n1ncn(-c2ccc(Br)cc2)c1=O +COC(=O)C(CNC(=O)C1CC1C)Oc1ccc(F)cc1 +CC(=O)Nc1ccc(NCc2cc3cc(C)c(C)cc3[nH]c2=O)cc1 +NC(=O)c1cncc(C#CC2(NC(=O)c3ccccn3)CCCCC2)c1 +CNC(=O)c1cc(S(=O)(=O)NC(C)(C)C)ccc1OC +CCCC(C)N(C)C(=O)CCc1nc2sc(C)c(C)c2c(=O)[nH]1 +O=C(Cc1ccc[nH]1)Nc1nc2cc3c(cc2s1)OCCO3 +Nc1cc(Cl)cc2c(N3CCOCC3)nccc12 +CCOc1ccc(C2=Nn3c(nnc3-c3ccco3)SC2)cc1 +CCC(=O)N1c2ccc(C(O)CN3CCOCC3)cc2CC1C +Cc1cc(C2CCC2)nc(NCCSc2nnnn2C)n1 +CCOC(=O)CC1Nc2cc(C(C)C)ccc2NC1=O +CC(C)C(=O)Nc1nc2ccc(Cl)cc2s1 +Cc1ccc(C(=O)CCC(=O)N=c2[nH]c3ccccc3[nH]2)cc1 +CCOc1ccc(CC2C(=O)Nc3c(C)cccc32)cc1OC +NC(=O)c1ccc(CSc2ncccc2C(=O)NCC2CC2)cc1 +CN(C)c1cccc(CNC(=O)c2cnc(C3CCCO3)s2)c1 +Cc1ccc(NC(=O)N(C)C)c(C(=O)Nc2cc(F)ccc2C)c1 +CN(CCOCC1CC1)C(=O)c1c[nH]nc1-c1cccc(Cl)c1 +CN(Cc1ccc(F)cc1)C(=O)c1ccc(OCC(F)F)nc1 +Clc1ccc2cccnc2c1CN1CCOC(Cn2cncn2)C1 +Cc1ccc(C(=O)N2CCCN(C)c3nc4ccccc4nc32)o1 +Cc1noc(-c2ccc(-c3ccnc4c3ccn4C)nc2)n1 +CC(C)(C)N1CC(C(=O)NCc2ccon2)CC1=O +COCc1nc(C(=O)Nc2ccc(C)cc2OC)cs1 +CCOc1ccc(C#N)cc1NC(=O)Cn1cncn1 +O=C(Nc1cc(Cl)ccc1Cl)c1cnccn1 +CC(Cc1ccc2ccccc2c1)NS(C)(=O)=O +CCOc1ccccc1OCC(=O)Nc1cccc(N)c1C +OC(c1ccccc1)c1nccn1Cc1ccccc1 +CCOC(=O)CC(Cc1ccccc1)c1ccccc1 +N#CCCN(Cc1ccccc1F)c1ccccc1 +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)OCC1CCCO1 +Cc1nn(Cc2nn(-c3ccccc3)c3c2CCC3)c(=O)c(C#N)c1C +COCCn1cc(NC(=O)c2ccc(-n3cc(C)cn3)cc2)cn1 +Cc1nc(C(C)C)sc1C(=O)NC(C)c1cccnc1 +O=C1CC(C(=O)N2CCCC2c2ccsc2)CN1Cc1ccco1 +Nn1cnnc1SCC(=O)N1CCCc2ccccc21 +CCS(=O)(=O)N1CCN(C(=O)CCC2CCCC2)CC1 +CCCOc1ncccc1CNC(=O)N1CC(C)OC(C)C1 +O=C(Cn1nnc(-c2cccnc2)n1)NCC1CCCO1 +Cc1cc(C)n(-c2nnc(SCC(=O)NCC(F)(F)F)n2N)n1 +CC(NC(C)c1cccc(C(F)(F)F)c1)C(=O)N(C)CCC#N +COC(=O)c1ncccc1OCc1cc(-c2cccs2)on1 +CC(=O)Nc1cc(NC(=O)NC2CCCCCC2)ccc1C +CCCC(C)c1nnc(NC(=O)CC(C)C)s1 +Cc1cc(C)n2nc(CC(=O)N(CC3CC3)C3CCCCC3)nc2n1 +Cn1cc(NC(=O)Nc2ccc(Cl)c(C(=O)NC3CC3)c2)cn1 +CCN(C(=O)Nc1ccc(C(=O)NC2CCOCC2)cc1)C1CC1 +COc1ccc(Cl)c2c1c(CC(N)=O)c(C)n2C +CCc1c(C)sc2nc(-c3ccc(-n4ccnc4)nc3)[nH]c(=O)c12 +CCCCNC(=O)NCCOc1cccc(F)c1 +CCc1ccc2c(c1)NC1(C=C(C)OC(N)=C1C(N)=O)O2 +O=C(Cc1ccccc1)NCCc1ccc(O)cc1 +Cc1nn(C)c(C)c1NC(=O)C1CCC(C(C)(C)C)CC1 +O=S(=O)(Cc1ccc(F)cc1)NCC#Cc1ccccc1F +Cc1ccc(OCc2occc2-c2nc(C3CC3)n[nH]2)cc1 +Cc1ccc2nc(C(=O)NC(c3nccn3C)C3CC3)cn2c1 +C=CCOCCNC(=O)c1cc(-c2ccccc2)no1 +CCCNC(=O)Nc1ccc(OC)c(OCC)c1 +Cc1nc(C(=O)N2CCOC3CCCCC32)nn1-c1ccccc1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3cccc4cc[nH]c34)c2)n1 +CCCSc1nc2nc(C)c(C(=O)OCC)cn2n1 +CC(=O)N(C)c1cccc(NC(=O)COc2cccc(C)c2C)c1 +O=C(COc1nnc2ccccn12)NCc1ccc(Cl)cc1 +Nc1nc(-c2ccc(F)c(F)c2)nc2c1CCCC2 +CC(=O)Oc1ccc(OCc2ccccc2)c(N)c1 +Cc1nnc2n1CCN(Cc1cc(-c3ccccc3)no1)C2 +COc1ccc(NC(=O)c2cc(C)n(C(C)C)c2C)cc1 +CNC(=O)Nc1ccccc1SCC(F)(F)F +COCCNC(=O)c1nnc(Cc2ccccc2Cl)o1 +CC(C)CNC(=O)C(C)NC(C)c1ccc(F)c(Cl)c1 +CNC(=O)Nc1cccc(NC(=O)c2sc3nccn3c2C)c1 +CC(OCc1ccccc1)C(=O)Nc1cccc(CO)c1 +Cc1cc(C)n2nc(SCC(O)CN3CCOCC3)nc2n1 +O=C(NCc1noc(-c2ccc(F)cc2)n1)C1CCC1 +Cc1ccc2nc(Nc3nc(C)c(CC#N)c(=O)[nH]3)nc(C)c2c1 +Cc1nc2ccccc2n1CCN1CCc2cc(F)ccc2C1 +CCc1cccc(NC2CCCc3c2cnn3C)c1 +O=C(Nc1nc2ccc(F)cn2n1)c1ccc(-c2cscn2)cc1 +Cn1nccc1C(=O)Nc1nnc(-c2cccs2)o1 +COc1ccc2c(c1F)C(c1cccc(C#N)c1)NCC2 +CC(=O)Nc1ccc(C)c(NC(=O)NC(C)CCCO)c1 +CC1CC(C)CN(c2nnc(SC(C)C#N)n2Cc2ccco2)C1 +CCc1ccc(NC(=O)N2CCN(S(C)(=O)=O)CC2)cc1 +CNC(=O)c1c(C)nc(N)nc1-c1ccccc1OCCOC +CCCCN(C)C(=O)CNC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1nc(C)c(C(=O)N2CCc3c(C)cccc32)o1 +Cc1nc(Cc2nn3c(C(F)(F)Cl)nnc3s2)cs1 +CC(=O)c1cccc(NC(=O)c2ccc(C)s2)c1 +COC(=O)c1cnc(C)n(Cc2nc(-c3cccc(F)c3)no2)c1=O +CC(Cc1ccccc1)NC(=O)Cc1ccccc1 +Nc1cccnc1Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 +CNC(=O)c1cccc(CNC(=O)CC2C=CCC2)c1 +Cc1[nH]ncc1CCCNC(=O)NCCc1c(F)cccc1F +CC(=O)N1CCCC1C(=O)Nc1ccc(F)c(-n2cccc2)c1 +COC(=O)CCn1c(C(C)(C)C)nc2cccc(F)c21 +Cc1cc(C(C)NC(=O)C(C)Sc2ccccn2)c(C)o1 +O=C(Nc1cccnc1)Nc1ccc(F)c(Cl)c1 +O=C(NCCCO)C1(c2cccc(Cl)c2)CC1 +CCOc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1OCC +CCc1nnc(SCc2ccc(C)cc2)n(N)c1=O +CS(=O)(=O)N1CCN(CCNC(=O)c2csnn2)CC1 +Cc1ccc(-c2nc3ccccc3n3nnnc23)cc1 +O=C(CNC(=O)c1cnccn1)NCCn1ccc2ccc(F)cc21 +COc1c(C2CCCN2C(=O)COc2cccnc2)c(C)nn1C +Cc1csc(CNC(=O)N2CCCCC2C)n1 +CCN(Cc1ccccc1)C(=O)Nc1cccnc1 +CC1=NC(=O)C2C(=N1)NC(=O)CC2c1cccc(Cl)c1 +Cc1cccc(OC(=O)CCNC(=O)C(C)(C)C)c1C +O=C(c1ccc(Cn2cccn2)cc1)N1CC=C(c2ccccc2)CC1 +CC(=O)c1ccc(Nc2ncnc(N3CCC(C)CC3)c2N)cc1 +O=C(CNS(=O)(=O)c1ccc2c(c1)CCCC2)NCc1ccco1 +CCC(C)c1ccccc1OCC(=O)Nc1cccn(C)c1=O +Cc1cccc(C(=O)N(CCC#N)Cc2cccnc2)c1 +Cc1ccc(F)c(OCC(=O)Nc2cccc(C(=O)NC3CC3)c2)c1 +COC(=O)c1cnc(NC(=O)Cn2c(C)cc3ccccc32)s1 +CCOc1ccc(CNC(=O)c2cc(F)cc3[nH]cnc23)cc1OC +COC(=O)CC(C)C(=O)c1ccc(OC)cc1OC +C#CCN(C(=O)c1cnn(-c2ccncc2)c1C)c1nccs1 +CCOc1ccc(CN(C)C(=O)CN2CCOc3ccccc32)cc1 +COC(=O)C(C#N)C(C#N)(C(=O)OC)C1CCCCCC1=O +NS(=O)(=O)c1ccsc1C(=O)N1CCc2ccccc2C1 +CC(C)CN1CCOC(CNC(=O)N2CCc3sccc3C2)C1 +CCOc1ccc(-n2nnnc2CNC(=O)CC2CCCCC2)cc1 +Cn1cccc(C(=O)Nc2ccc(-n3ccnc3)nc2)c1=O +CC(Sc1ncnc2nc[nH]c12)C(=O)Nc1ccc(Cl)cc1 +O=C(CCc1c[nH]c2ccccc12)OCc1noc(-c2ccco2)n1 +COc1ccc(C(=O)NCCO)cc1S(=O)(=O)N(C)C +Cc1c(CNC(=O)Nc2nc(C)n(C(C)C)n2)cnn1C +CC1(C(=O)N2CCC(OCc3ccccc3F)CC2)CCCO1 +COc1cc(OC)cc(C(=O)NCC(OC)c2ccccc2)c1 +CCOC(=O)CNC(=O)Nc1ccc(F)cc1F +CC(=O)NC1CCN(Cc2cc(=O)c3c(C)ccc(C)c3[nH]2)C1 +CCC(C)C(=O)NCc1ccccc1-n1ccnc1 +Nc1nccnc1C(=O)N1CC=C(c2c[nH]c3ncccc23)CC1 +CCCn1c(NC(=O)C2CCOC2)nc2ccccc21 +Cc1cc(NC(=O)c2ccc(Cl)c(N)c2)on1 +CC(=O)N1CCc2ccccc2C1CC(=O)NC(C)c1ccccn1 +COc1ccccc1NC(=O)CSc1cccc(N)c1 +CCCc1n[nH]c(SCc2cccc(C(=O)N3CCCCC3)c2)n1 +COc1ccc(-n2ccc(C(=O)Nc3nccs3)n2)cc1 +CCn1c(SCCCO)nnc1-c1cccs1 +Cc1cccc(NC(=O)NCc2cccc(C(N)=O)c2)c1 +Cc1noc(-c2cccc(NC(=O)COc3ccccc3)c2)n1 +Cc1cc(Br)ccc1NCC(O)c1ccccn1 +Nc1ccc(F)c(NC(=O)CCOCC(F)(F)F)c1 +O=C(CCc1cccnc1)N1CCC(CC(=O)N2CCCC2)CC1 +CC(=O)c1c(SCC(=O)Nc2cccc(F)c2)nc(=O)[nH]c1C +CC(CCCO)NC(=O)NCC(O)c1c(Cl)cccc1Cl +COc1ccc(-c2cccc(CC3NCCNC3=O)c2)cc1 +CCCNC(=O)c1cc2c([nH]c1=O)CC(c1cccs1)CC2=O +CCc1nc(C(C)NC(=O)Nc2cc(OC)ccc2F)cs1 +c1ccc(CN2CCCC2c2ccnc(Nc3cnccn3)n2)cc1 +C=CCNS(=O)(=O)c1cc(Cl)c(OCC)cc1Cl +CCOC1Cc2ccccc2N(C(N)=O)c2ccccc21 +COC1(O)C(=O)c2ccccc2OC1(OC)c1ccc(Cl)cc1 +COc1cc(C(=O)N(C)C)ccc1NC(=O)c1ccsc1 +Cc1ccnc2nc(C(=O)OCc3nccs3)nn12 +Cn1nnnc1SCCC(=O)Nc1ccc(F)cc1Cl +Cc1ccccc1OCCN(C)S(=O)(=O)N1CCOCC1 +N#CCOc1ccc(C2NC(=O)c3ccccc3N2)cc1 +COC(=O)Cc1csc(COc2ccc(OC)cc2)n1 +CC(C)(C)CC(=O)NCC(=O)NCC1CN2CCCCC2CO1 +Cc1ccccc1C1CC1C(=O)NCCCN1CCOCC1 +CC(=O)c1cccc(NCC(=O)N2CCOCC2)c1 +Cc1nc(C)c(C(=O)OCc2cc(=O)n3c(C)csc3n2)s1 +O=C(NCC1OCC2CCN(c3ncccn3)CC21)c1cscn1 +N#CCOc1cccc(CC(=O)NCc2cnn(-c3ccccc3)c2)c1 +COc1ccc(C(=O)NCc2ccc(-c3csc(C)n3)cc2)cc1 +Cc1c(C(=O)Nc2cccc3cn[nH]c23)cnn1-c1ccccc1 +CC(OC(=O)c1ccc(-n2ccnn2)cc1)c1nc2ccccc2n1C +COc1ccc(Cl)cc1NC(=O)Cn1nc(C)cc1C +O=C(NCc1ncccc1F)c1scnc1C1CC1 +O=C1CN=C(Nc2cccc(C(F)(F)F)c2)N1Cc1cccs1 +c1ccc(CCCOc2ccc(-n3cncn3)cc2)cc1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)NCCC1=CCCCC1)O2 +CCc1ccc(CNC(=O)CNC(=O)OC)s1 +Cc1cc(C(=O)N2CCN(S(=O)(=O)Cc3ccccc3)CC2)on1 +CN(C)C(=O)CCN1C(=O)C(=O)c2c(Br)cccc21 +C=CCn1nc(C)c(Cc2c(C)nn(CC=C)c2C)c1C +COc1ccc(CSc2nnnn2C2CC2)c(Cl)c1 +O=C(NCc1ccccn1)Nc1ccccc1N1CCCCC1 +Clc1cccc(-c2nc(-c3ccc(-n4ccnc4)nc3)no2)c1 +CN(C)C(=O)CCSc1nnnn1-c1ccccc1 +CC(=O)NCCCNC(=O)Nc1cccc(F)c1F +COc1ccc(S(=O)(=O)Nc2cccnc2)cc1Br +CN(Cc1ccc(C(N)=O)cc1)C(=O)c1ccc(OC(F)F)cc1 +CC(C)NC(=O)c1ccccc1NCC(=O)N1CCCC(C(N)=O)C1 +COCCn1cc(NC(=O)c2ccc3ccccc3c2O)cn1 +CC1CCN(C(=O)c2cc(NC(=O)C(C)(C)C)c(=O)n(C)c2)CC1 +Cn1cnnc1-c1cccc(NC(=O)CCSc2ccccn2)c1 +Cc1nn(C)c2[nH]nc(NC(=O)c3ccc(C#N)cc3)c12 +CN(Cc1ccccc1F)C(=O)CNc1ccc(F)c(F)c1F +COCCNC(=O)N(Cc1ccc(O)c(OC)c1)C1CC1 +COc1ccc(S(=O)(=O)NCCc2ccsc2)cc1C +CCC(C)C(C)NC(=O)Nc1cccc(N2CCOC2=O)c1 +Cn1cc(CN2CCCCC2c2ccnc(N)n2)cn1 +CCn1c(SCC(=O)NC2CC2)nnc1-c1ccccc1C +CCc1nnc(NC(=O)N(C)CCc2ccccc2)s1 +Cc1nc(COC(=O)c2ccc(OCC(F)F)nc2)oc1C +Cc1ccc(C(=O)NCCNC(=O)c2ccc3ccccc3c2)cn1 +CCCC1CN(C(=O)c2sc3ncn(C)c(=O)c3c2C)CCO1 +Cc1csc(NC(=O)C2CC(=O)N(c3ccc(F)cc3F)C2)n1 +O=C1CCC(C(=O)N2CCN(Cc3ccccc3)c3ccccc32)O1 +CCCc1cc(NC(=O)C(C)Oc2ccc(SC)cc2)n[nH]1 +c1ccn2cc(-c3ccc4c(c3)OCCO4)cc2c1 +O=C(NCCc1cccs1)c1ccc2ncccc2c1 +CNC(=O)c1cccc(NC(=O)CNCc2ccccc2)c1 +O=C1C(=O)N(Cc2ccccc2Br)c2ccc(F)cc21 +O=C(NCCCC(=O)N1CCc2sccc2C1)c1ccsc1 +COc1cc(C2(C(=O)Nc3cnn(CC(F)F)c3)CC2)ccc1C +O=C(c1ccccc1)N1CCN(Cc2ccc(F)c(F)c2)CC1 +Cn1ccnc1C(=O)N1CCCC(C)(c2ccccc2)C1 +CCCn1nnnc1NC(=O)c1cccc(Br)c1 +Cc1ccc(C(=O)Nc2ccc(C(=O)N3CCOCC3)cc2)o1 +O=C(CCc1ccccc1)N(Cc1ccco1)CC1CCCO1 +O=C(Nc1ccccc1)c1ccccc1C(=O)N1CCCCC1 +CCOC(=O)C(O)(c1cc(C)c(O)c(C)c1C)C(F)(F)F +Cc1cc(NC(=O)Cc2n[nH]c3ccccc23)c2ncccc2c1 +CCn1c(N)c(NCCS(N)(=O)=O)c(=O)[nH]c1=O +COc1ccc(OC)c(C2CCN(C(=O)c3ccc(=O)n(C)n3)C2)c1 +CC1CCCCC1NC(=O)COC(=O)c1cccnc1-n1cncn1 +Cc1ncn(-c2cc(NCCNC(=O)c3ccccc3)ncn2)c1C +Cc1cc(=O)[nH]c(Nc2nc(C)c3ccccc3n2)n1 +O=c1onc(-c2ncccn2)n1CCS(=O)(=O)c1ccccc1 +Fc1cc(Cl)c2c(c1)C(c1nc[nH]n1)NCC2 +Cc1cc2cccc(C(=O)N3CCCCC3c3cccnc3)c2o1 +COC1CCC(c2cccc(C#N)c2)n2nc(N)nc21 +CCC(=O)Nc1nonc1OCCn1nnc(-c2ccccc2)n1 +CCNS(=O)(=O)c1ccc2c(c1)N(CC)CCO2 +COc1ccc(C(=O)NCc2cc(=O)oc3cc(F)ccc23)cc1 +CCC(C)CN(C)C(=O)NCC(=O)N1CCc2ccccc21 +CN(C)C(=O)c1cc(NC(=O)COc2ccccc2Cl)ccn1 +COc1ccc(NC(=O)C(C)Oc2cccc(C)c2)cn1 +Nc1cc(-c2nc(-c3ccccc3N)cs2)ccn1 +Cc1cc(C(=O)Nc2cccc(OC(F)(F)F)c2)c(C)o1 +Cc1ccc(N2CC3CCC2C3OCc2ccccn2)nn1 +CCN(CC(=O)Nc1ccccc1OC)C(=O)c1cccnc1 +COc1ccc(NC(=O)c2nc3ccccc3nc2OC)c(OC)c1 +Cc1ccc(NC(=O)c2cnn(-c3ccccc3C)c2)c(O)c1 +CCn1cc(-c2ccc(C)cc2)cc1C(=O)NCc1cccnc1 +OC1CN(Cc2ccccc2-c2ccco2)CCC1N1CCOCC1 +O=C(NCc1ccco1)C1CCCN(CC(F)(F)F)C1 +CN(CC1CCCN(C(=O)OC(C)(C)C)C1)c1ncccn1 +N#Cc1cc(F)ccc1NCc1ccc(CS(N)(=O)=O)cc1 +CCc1ccc(S(=O)(=O)N(C)c2cccc(N)c2)s1 +CNc1nc(C(=O)N2CCCC(O)(CO)C2)cs1 +CC(=O)Nc1ccc(-c2cc(C(=O)NC(C)C)c3ccccc3n2)cc1 +Cc1cc(-c2nnc(NC(=O)CNC(=O)c3ccccc3)o2)c(C)o1 +Cc1cc(C)n2nc(SCC(=O)N3CCCC3)nc2n1 +CCC(=O)c1cccc(S(=O)(=O)NC2CCCC2)c1 +C=CCNC(=O)C(C)N(c1cccc(C)c1)S(C)(=O)=O +CN(CCC#N)C(=O)Nc1ccc(Oc2ncccn2)cc1 +COCC(=O)c1cc(Br)c2c(c1)CCCCO2 +CC(=O)N1CCCC1C(=O)Nc1ccc(Br)c(C)c1 +CC(CNC(=O)c1noc2c1CCCC2)n1cncn1 +Cc1ccc(C(=O)Nc2ccccc2F)cc1NS(C)(=O)=O +Cc1c(C(=O)Nc2ccccc2C(F)(F)F)cnc2ccnn12 +Cc1nc(CNC(=O)c2ccn(C3CCCC3)n2)c(C)s1 +CCOC(=O)CCCSc1nc(C)cc(C)n1 +O=C(NCCCN1CCCC1=O)c1sc2ccccc2c1Cl +O=C(Nc1ccc2c(c1)COC2)N(CCO)C1CCCCC1 +CN(Cc1ccoc1)c1nc2c(cc1C#N)CCC2 +c1cnn(-c2ccc(-c3noc(C4CCCC4)n3)cn2)c1 +Cc1ccc(C(=O)Nc2c(C)nc3sccn3c2=O)cc1 +CNC(=O)NCC(=O)N1CCN(C(=O)CCC(C)C)CC1 +COc1ccc(C=CCCC(C)(C)O)cc1NC(C)=O +COC(=O)Cn1nc(CO)cc1-c1ccc(Cl)cc1 +Cc1cc(N)nc(-c2ccc(OCC(C)C)cc2)n1 +COc1ccccc1CC(C)(C)NC(=O)CCn1cc(C)cn1 +COc1ccccc1C(=O)NC(C#N)c1cccc(C)c1 +Cc1cc2ncn(C(C)c3nc(-c4cnn(C)c4)cs3)c2cc1C +Cc1n[nH]c(C)c1CCOC(=O)c1cccc2cc[nH]c12 +Cn1c(Sc2ncc(C(C)(C)C)o2)c(C#N)c(=O)n(C)c1=O +CCOc1ccc(NC(=O)Nc2ccc(C(N)=O)cc2)cc1 +CCn1c(CNC(=O)c2cnn(C(C)(C)C)c2)nc2ccccc21 +N#Cc1ccc(Cn2c(C#N)nc3ccc(F)c(F)c32)cc1 +COC(=O)C(NC(=O)Cc1cccc(O)c1)C(C)C +CCOc1ccc(C(=O)OCC(=O)NC2CCCC2)cc1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3ccnn3CC(C)C)cc2)n1 +CCn1nc(C(C)C)cc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +CCCn1nc(C(=O)Oc2ccc(Cl)cc2)ccc1=O +COCC(O)CN(C)C(=O)C1CCN(c2ccc(C)c(C)c2)C1=O +CC(C)COc1ccc(C(=O)N(CC(N)=O)C2CCCC2)cn1 +COC(=O)C(C)CNC(=O)Nc1cccc(F)c1C +Fc1ccc2c(c1)CCNC2c1ncccc1Cl +CSc1nnc(NCc2ccccc2C)s1 +COc1ccc(C(=O)COc2ccc(C#N)c(F)c2)c(OC)c1 +COc1ccc(NC(=O)CNc2ccc(C)cc2)c(OC)c1 +CC1(C)Oc2ccc(N)nc2N(CC(O)CO)C1=O +CC(CNC(=O)c1ccc(F)c(F)c1)Cn1cccn1 +CC(C)NC(=O)Cc1csc(NC(=O)c2ccco2)n1 +CCc1noc(C)c1C(=O)NCc1ccccc1F +COCc1noc(CNc2cc(-c3ccccc3)nc3ccnn23)n1 +Cc1cccc(CN2CC(N3CCCC3=O)C3OCCCC32)n1 +Cc1nc(Cc2nc(N)c3c(n2)CCCC3)cs1 +Cc1nn(C)c(C)c1CC(=O)N(C)c1ccc(Cl)cn1 +O=C(c1cnccn1)N1CCC2(CC(=O)N(c3cccc(F)c3)C2)C1 +CCOc1ncccc1C(=O)Nc1ccc(S(C)(=O)=O)cc1C +Cc1csc(-c2ccc(CNC(=O)c3ccnn3C)cc2)n1 +CC(O)c1cc(F)ccc1N(C)Cc1cccnc1 +CCC1(C#N)N=C(c2ccccc2)c2ccccc2N1C(=O)OC +CN(Cc1ccncc1)C(=O)NCC1(N2CCOCC2)CCCCC1 +CC(Cn1nc(-c2ccco2)ccc1=O)C(=O)Nc1cccnc1 +Cc1cc(C(O)C(=O)NCC2CCCO2)ccc1F +COc1ccc(Nc2cc(C#N)ccn2)c(OC)c1 +O=C(Nc1ccc(O)cc1)c1cccc(OCC(F)F)n1 +COc1ncccc1C(=O)Nc1ccc(C(N)=O)cc1 +CCOC(=O)CNC(=O)NCc1cccc(F)c1 +O=C(Cn1nc(-c2cccs2)ccc1=O)Nc1cccc(Cl)c1 +CC1CN(CCCNC(=O)NC(C)c2ccccc2)CC(C)O1 +O=C(NCCCc1nc2ccccc2s1)c1ccc2[nH]nnc2c1 +Cn1cnnc1SCCS(=O)(=O)c1ccc(C(C)(C)C)cc1 +CC(=O)c1ccc(F)c(NC(=O)CCc2ccco2)c1 +CC(O)(CNC(=O)c1ccccc1Cl)c1ccco1 +Cc1noc2ncc(C(=O)OCCc3cccs3)cc12 +CCNC(=O)NC1(C(=O)NCc2cccc(C(=O)NC)c2)CCCC1 +O=C(COc1ncnc2sccc12)N(C1=CCCCC1)C1CC1 +Cc1csc(C(C#N)C(=O)c2cnc3ccccn3c2=O)n1 +CC(C)(C)OC(=O)N1CCCCC12CNC(=O)C2 +CCN1CCOC(C(=O)NC(c2ccccc2F)C2CCCC2)C1 +Cn1cc(C(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)c(C(C)(C)C)n1 +COc1cccc(C(=O)NCC(=O)NC(C)C)c1O +CCOC(=O)c1ccc(NC(C)C2CCCO2)nc1 +CNC(=O)c1cccc(CCNC(=O)N2CCCC2c2ccc[nH]2)c1 +COc1ccc2nc(N3CC(C(=O)NCC(F)(F)F)C3)sc2c1 +CN(Cc1cscn1)C(=O)Nc1cccc(N)c1 +COc1ccc(C)cc1NC(=O)c1c(C)oc2ncn(C)c(=O)c12 +COc1ccc(C(=O)C2CCC(=O)O2)c(OC)c1 +COc1ccccc1CC(=O)N(C)Cc1nccn1C(F)F +COCCN(C)C(=O)c1ccc(N2CCNC2=O)cc1 +COc1ccc(Cl)cc1CS(=O)(=O)NCCc1ccccn1 +Cc1ccc(C#N)c(N2CCC(=O)N(CC3CC3)C(C(C)C)C2)n1 +O=C(NCCc1cscn1)c1cccc(F)c1F +Cc1sc(-c2ccco2)nc1C(=O)N(CC(N)=O)C1CCCC1 +COc1cccc(C(=O)OCc2nc(C)no2)c1F +COc1ccc(C(C)NC(=O)c2nnn(-c3ccccc3)c2C)cc1 +O=C(Nc1ccc(F)cc1)c1cc2cc(F)ccc2[nH]1 +CN(CC(=O)OCc1ccc(C#N)cc1)C(=O)c1cccs1 +Cc1occc1-c1nnc(SCC(=O)N2C(C)CCCC2C)n1N +COc1cccc(-c2cn3ccn(-c4cccc(F)c4)c(=O)c3n2)c1 +FC(F)(F)c1nccc(N2CCC(OCc3ccccc3)CC2)n1 +Cc1ccccc1-n1c(C)nnc1SCC(=O)N1CCC(C)CC1 +CCn1cnnc1-c1ccccc1NC(=O)c1cnc2ccc(C)cn12 +CN(C)c1cc(NC(=O)c2ccccc2F)c(Cl)cc1N +CC(C)(C)OC(=O)N1CCC(Oc2ccccc2N)C1 +CNC(=O)C(C)NC(=O)c1cc(N)cn1C(C)C +COc1ccc(C)cc1-n1c(C)c(C)c(C#N)c1N +Cn1c(=O)n(C)c2cc(NC(=O)Nc3ccccc3F)ccc21 +N#CC(NC(=O)c1ccnc(OC2CCC2)c1)c1cccc(Cl)c1 +CCCOc1ccc(CNCC2CN(C)CCO2)cc1 +Cc1nc2c(c(=O)[nH]1)CCN(C(=O)c1coc3c1C(=O)CCC3)C2 +COC(=O)c1ccc(NC(=O)NCc2cccs2)c(C)c1 +COCCNC(=O)CCC1CCCN(C(=O)Nc2cccc(C)c2)C1 +Cc1cc(C)nc(-n2nc(-c3ccccn3)cc2N)n1 +COc1ccccc1CN1C(=O)OCC1C(=O)NC1CC1 +CCCNC(=O)CCNS(=O)(=O)c1ccc(C)cc1C +Cc1ccc(C)c(NC(=O)CN(C)C(=O)c2cccs2)c1 +CCOc1cccc(CN(C(=O)Cn2cccnc2=O)C2CC2)c1 +N#CCOc1cccc(CC(=O)Nc2ccccc2C#N)c1 +Cn1cc(C(=O)NCCN2CCOCC2)c2ccccc2c1=O +Cc1cccc(O)c1NC(=O)c1ccncc1Cl +Cc1ccc(CN2CC(C(=O)Nc3ncc(C)s3)CC2=O)cc1 +Cc1cc(C(=O)NCc2cc(C)oc2C)c2c(C)nn(C)c2n1 +CNC(=O)Nc1ccc(NC(=O)c2cn3cccnc3n2)cc1 +CCOc1ccccc1CC(C#N)C(=O)NCC(C)C +Cc1cc(C)n(CCNc2nccc(-c3c(C)nn(C)c3C)n2)n1 +CCN(C(C)COC)S(=O)(=O)c1cc(Cl)ccc1Cl +CC(C1CC1)N(C)C(=O)CCc1nc(-c2cccnc2)no1 +COc1ccc(C(Cc2ccccc2C)NC(C)=O)cc1OC +CC(c1ccccc1)N(CC1CCC1)C(=O)C1COCCO1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(C)o1 +Cc1ccc(OS(=O)(=O)N(C)C)c2c1C(C)CC2=O +COC(=O)c1cn(-c2ncccc2-c2nc(C)no2)cn1 +CC(C)(NC(=O)NCCCCn1ccccc1=O)c1cccc(F)c1 +CCN(CC(F)(F)F)C(=O)c1cc(N)ccc1OC +COc1ccc(C2=CCN(C(=O)NC(C)c3nncn3C)CC2)cc1 +O=C(Nc1nc(-c2ccc3c(c2)OCO3)cs1)c1ccc(=O)[nH]c1 +CCOC(=O)NCc1ccc(S(=O)(=O)Nc2ccc(C)cc2)cc1 +COc1cc(C)ccc1NC(=O)N1CCN(CC2COCCO2)CC1 +O=C(Nc1nnc(C2CC2)s1)NC1CCCCCC1 +Nc1ccc2c(c1)CCN2S(=O)(=O)c1cccnc1 +CC1=NC(=O)C(CCC(=O)NCCc2ccc3c(c2)OCO3)C(C)=N1 +COc1ccc(C(C)C)cc1Cn1c(=O)oc2ccc(N)cc21 +O=C(NCc1ccc(Cl)cc1)NCc1ccsc1 +COCCOc1ncccc1NCc1cccs1 +CC1=C(c2ccccc2)S(=O)(=O)N=C1N1CCCC(C)C1 +CC1CCCN(C(=O)CCn2cnc3c(cnn3C)c2=O)C1 +CCn1ncc2cc(C(=O)N3CCOCC3)c(N)nc21 +C#CCN1CCN(C(=O)NC(C)c2nc(C(C)(C)C)no2)CC1 +CCC(NC(=O)COc1cccc(C)c1C)c1ccccc1 +Cc1cc(C(=O)NC(C)C(=O)NC(C)(C)C)c(C)n1Cc1ccco1 +CNC(=O)CCNC(=O)c1ccccc1N1CCOCC1 +CCOCC1CCCC12CN(Cc1c(C)noc1C)CCO2 +CCN(C)c1ccc(C(=O)N(C)Cc2ccc(C(=O)NC)cc2)cc1 +COc1cc2[nH]c3c(=O)n(Cc4ccccn4)cnc3c2cc1OC +CC(C)CCc1nc(-c2ccc3c(c2)CC(=O)N3C)cs1 +Cc1cc(NC(=O)N(CC2CCOC2)C2CC2)no1 +Cc1cccc(C(=O)N2CCC3(CC(Oc4cccnc4)CO3)C2)n1 +COC(=O)c1c(C)[nH]c(C(=O)Cn2nnc(-c3ccsc3)n2)c1C +C=CCn1c(C(C)NC(=O)c2ccncc2)nc2ccccc21 +CCC1=C(C(=O)OC)C(c2ccc(F)cc2)NC(=O)N1 +O=C(c1ccc(Cn2cncn2)cc1)N1CCOC(c2ccccc2)C1 +Cc1cc(CO)nn1-c1cc(Cl)cc(Cl)c1 +COc1ccnc(NC(C)C(=O)NCc2ccco2)n1 +Cc1cccc(NC(=O)c2ccc(Cl)c(S(C)(=O)=O)c2)n1 +COc1ccc(F)c(NC(=O)CCCOc2cccnc2)c1 +COc1ccc(-c2csc(NC(=O)c3ccncc3)n2)cc1F +CC(C)Nc1ncnc(NC2CCCCCC2)c1N +CC(NC(=O)N1CCOC(C#N)C1)C(=O)N1CCCCC1C +CCOC(=O)c1cc(C(=O)Nc2cc(C)on2)n(C)n1 +Cc1ccc(F)c(S(=O)(=O)NCCCn2cccn2)c1 +CCNC(=O)CNC(=O)C1(c2cccc(Cl)c2)CCOCC1 +C=CCN1C=C(OC(=O)c2ccccc2)c2ccccc2S1(=O)=O +NC(=O)c1cccc(CNC(=O)CSc2nc3ccccc3o2)c1 +CCC(C)NC(=O)NCc1ccc(S(=O)(=O)NC)s1 +CC(C)NC(=O)NCc1ccc(C(=O)Nc2ccc(F)cc2)cc1 +CCNS(=O)(=O)c1cccc(C(=O)N2CCc3ccccc32)c1 +CNC(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CC(Sc1nccn1C)C(=O)N(C(C)C)C(C)C +Cc1ccc(OCC#CCNC(=O)CSc2ccc(F)cc2)cn1 +COc1ccc(NC(=O)CC2NC(=O)c3ccccc3N=C2O)cc1 +Cn1c(=O)oc2cc(Cl)c(Br)c(Cl)c21 +CC(Cc1ccccc1F)NC(=O)N(C)Cc1ccncc1 +CCSc1ccccc1NC(=O)NCC(C)(O)c1ccco1 +CC(NC(=O)N(C)CCCOc1ccccc1)c1ccncc1 +CCOc1ccc2nc(NC(=O)c3cccnc3OCC)sc2c1 +CC1(C)CN(C(=O)c2ccc(N3CCCS3(=O)=O)cc2)CCO1 +CCN(CC)C(=O)CSc1nnc(-c2cccc(Cl)c2)o1 +O=C(NCCC(=O)N1CCCC1)c1nc2c(F)cccc2s1 +O=S(=O)(NCc1ccco1)c1ccc2c(c1)OCCCO2 +CC(C)C(=O)Nc1ccc(CNC(=O)NC2CCCCC2)cc1 +CCc1ccc2c(c1)C(CCNC(=O)CCc1ccsc1)C(=O)N2 +COCCn1cc(NC(=O)N2CCN(S(C)(=O)=O)CC2)cn1 +COc1ccc(-c2ncnc(C)c2N)c(OC)c1C +Cc1cccc(OCCCSc2nnc(-c3ccoc3C)n2N)c1 +COC(=O)c1ncn(Cc2ccc(F)cc2Cl)n1 +CC(C)CSc1nc(Cc2cccs2)n[nH]1 +Cc1nc(-c2cccc(CNC(=O)C(C)C3CCOCC3)c2)n[nH]1 +COc1ccc(C(C)=O)cc1CC(=O)OCc1nc(C)no1 +CCN(CC)C(=O)c1sc(NC(=O)c2cccnc2)c(C#N)c1C +CCc1ccc(NC(=O)C2(O)CCCC2)cc1S(N)(=O)=O +CCC(C)C(=O)Nc1nc(C)c(-c2nccn2C(F)F)s1 +CC(=O)c1cccc(S(=O)(=O)NC(C)CN2CCOCC2)c1 +CC(C)(C)c1noc(CCCC(=O)Nc2ccnn2C(C)(C)C)n1 +COc1cc(CNC(=O)c2[nH]c(C)c(C(C)=O)c2C)ccn1 +COc1ccc(OCc2nc3cc(F)cc(N)c3o2)cc1 +CCCCn1nc(C(=O)Nc2ccc(C)cc2Cl)ccc1=O +Cn1c(=O)c2c(ncn2CC(=O)OCC(=O)c2ccc[nH]2)n(C)c1=O +NC(=O)c1snc(-c2ccccc2Br)c1N +CC(C)(C)C(=O)NCCS(=O)(=O)NCC1CCC1 +CC(O)(CNC(=O)NC(c1ccc(F)cc1)C1CC1)c1ccco1 +C=CCCC1NCCc2cc(Cl)c(OC)c(OCC)c21 +CC(C)(C)OC(=O)N1CCC(C(=O)OC2CCCC2)CC1 +O=C(CCCOc1cccc(F)c1)N1CCC(c2cn[nH]c2)CC1 +COC(C)(C)c1noc(-c2ccc(-c3ccccc3)[nH]c2=O)n1 +N#Cc1cccc(NC(=O)C2CC2(Cl)Cl)c1 +CCS(=O)(=O)NCCNC(=O)CC1CCCCC1 +COc1ccc(-c2nc3cc(CO)ccc3o2)cc1OC +CC(=O)Nc1ccc(CC(=O)Nc2cc(Cl)ccc2C(N)=O)cc1 +Cc1cc2ncn(CC(O)CN(C)S(=O)(=O)C(C)C)c2cc1C +COC(=O)c1ccc(C)c(NC(=O)c2ccc3c(c2)OCCO3)c1 +Cc1cc(C)cc(CCNC(=O)c2cccnc2N(C)C)c1 +O=C1N=CC=CC1C1Nc2cc(Cl)ccc2N1Cc1ccccc1 +Cc1nc(CCOc2ccccc2N)n2ccccc12 +CCc1cc2c(NC(C)(C)CO)ncnc2s1 +c1cn2c(NC3CCCC3)c(-c3ccsc3)nc2cn1 +O=C(NCC(O)c1cc(F)ccc1F)c1ccc(F)cc1 +[H]N=c1oc(-c2ccccc2)nn1Cc1ccccc1 +Cc1csc(NC(=O)COc2c(C)cccc2C)n1 +COC(=O)c1cccc(OS(=O)(=O)c2ccc(C)cc2)c1 +CC1CN(C(=O)c2cc(F)cc3[nH]cnc23)CC(C)O1 +COCC1CN(C(=O)c2cc(C)no2)Cc2cncn2C1 +CCCC1=C(C(=O)OCC)C(c2cccs2)NC(=O)N1 +Nc1nonc1C(=O)Nc1cc(Cl)c(Cl)cc1Cl +CCn1nc(C(=O)Nc2ccc(F)cc2)c(=O)c2cc(Cl)ccc21 +COCc1cc(C(=O)NC(C)C(=O)Nc2ccccc2)ccc1F +Cc1c(C)n(CCc2ccccn2)c2ncnc(N)c12 +CCn1cc(C2=Nn3c(nnc3C(F)(F)F)SC2)c(C)n1 +CCc1ccc2nc(NC(=O)CCn3ccccc3=O)sc2c1 +O=C(NC1CC1)c1ccc(S(=O)(=O)c2ccccc2)s1 +CC(C)N(C(=O)C1CN(C(=O)c2cccs2)C1)C1CCCCC1 +CC(=O)Nc1cccc(NC(=O)CNC(=O)Cc2ccccc2)c1 +CCSc1ccc(S(=O)(=O)N(C)CCO)cc1 +CC(Oc1cccc(OCc2ccccc2C#N)c1)C(N)=O +CC(C(=O)NC1CCN(c2ccccc2Cl)C1=O)c1cccs1 +CCOC(=O)C1CCCN(C(=O)C(C)N2CC(C)OC(C)C2)C1 +Cc1ccc(N2CCC(C(=O)N3CCN(C(C)C)CC3)C2=O)cc1C +O=C(NCc1cccnc1)c1cc(-n2cccc2)ccn1 +Clc1cccc2nc(C3CC3)n(CC3CCCO3)c12 +Cc1c(C(=O)Nc2ccc(F)c(-n3cccc3)c2)cnn1C +Cc1cccc(NC(=O)Cn2nc(C(F)(F)F)n(C)c2=O)c1C +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)N(C)C(C)C +Cn1nccc1C(=O)Nc1ccn(Cc2ccccc2F)n1 +Cc1c(F)cccc1NC(=O)CSc1nc2ccc(N)cc2s1 +NC(=O)C1CCCN(C(=O)c2cc(N)ccc2F)C1 +O=C(Nc1cccc(Cl)c1)c1ccc(N2CCOCC2)nc1 +CC(C)(C)C(NC(=O)Nc1cc(F)c(F)cc1F)C(N)=O +Cc1noc(C(C)C)c1C(=O)NCCCOC(C)C +Oc1cccc(C2CN(Cc3cccc4cn[nH]c34)CCO2)c1 +Cc1cccc(C(=O)NCC(=O)Nc2ccc(F)cc2)c1 +N#CCc1cc2ccccc2nc1N1CCOCC1 +CCC(C(=O)OC(C)C)N1C(=O)COc2ccc(N)nc21 +Cc1nn(C)c(C)c1CCNC(=O)NC(C)Cc1ccccc1F +CC1(C(=O)Nc2cccc3ncccc23)Cc2ccccc2C(=O)O1 +COc1c(CNC(=O)NCC2(c3ccccc3F)CC2)c(C)nn1C +CCn1cnnc1CCNc1ncnc2sc(C)c(C)c12 +COc1ccccc1C(C)(C)CNC(=O)CC1CCCO1 +O=c1[nH]c2ccsc2c(=O)n1CCCc1ccccc1 +CCOc1ccc(C(=O)NCC(=O)Nc2ccnc(C)c2)cc1 +O=C(COc1ccc2c(c1)CCC2)NC1CCCCC1 +CCOC(=O)CC(C)CNC(=O)N1CCCC2(CC=CCC2)C1 +Cc1ocnc1CNC(=O)Nc1c(C)n(C)n(-c2ccccc2)c1=O +Cc1ccc2cccc(C(=O)Nc3cccc(F)c3)c2n1 +CCS(=O)(=O)c1ccc(NS(=O)(=O)N2CCCCC2)cc1 +O=C(CN1c2cccc3cccc(c23)S1(=O)=O)NCc1ccco1 +CCCNC(=O)N1CCc2c(c(-c3nc(C4CC4)no3)nn2C)C1 +CC(=O)N1CCC(NC(=O)NC(C)c2ccco2)CC1 +COc1ccc(CNC(=O)c2c(Br)cnn2C)cc1 +CCN(CCNC(=O)COC)c1cccc(C)c1 +CCCN(CC1CC1)C(=O)Nc1cc(NC(C)=O)ccc1OC +Cn1c2c(c(=O)n(C)c1=O)CCC(c1ccccc1)O2 +COc1ccc(C)cc1NC(=O)NCc1ccccc1-n1ccnc1 +CC(Oc1c(N)cc(F)cc1Br)C(=O)N(C)C +COc1ccc(S(=O)(=O)NCC(O)c2ccsc2)cc1Cl +CCN(CCC#N)C(=O)COc1ccccc1OC +CCOc1ccccc1C1CC(c2ccccc2)Nc2nc(N)nn21 +COc1ccc(CNc2ccccc2-n2ccc(C)n2)cc1O +COc1ccc(-n2nnc(CO)c2C(C)C)cc1Cl +CN(Cc1csc(-c2ccccc2)n1)C(=O)CCn1cnnc1 +O=S(=O)(NCc1ccc(Cn2cncn2)cc1)c1ccc(F)cc1 +COc1ccc(CC(=O)N2CCOC23CCCCC3)cc1 +CCC(=O)N1CCN(CCOc2ccccc2Br)CC1 +Cn1cnnc1SCc1nc(N)nc(Nc2ccc(Cl)cc2)n1 +COc1cc(OC)cc(N2CCC(C(=O)NCC(C)C)C2=O)c1 +COc1ccc(-c2ccnc3[nH]ccc23)cc1CO +CC1CCCC(C(=O)OCCNc2cccnn2)C1 +CC1(NS(=O)(=O)N2CCCCCC2)Cc2ccccc2C1 +CCCc1cc(C(=O)Nc2c(C)nn(Cc3ccccc3)c2C)no1 +Cc1nn(C)c2nc(C(C)C)cc(C(=O)N3CCC3)c12 +O=C(c1cc2c([nH]c1=O)CCC2)N1CCN(CC2CCCO2)CC1 +CCCN1C(=O)C(C(C)C)Oc2ccc(C(C)=O)cc21 +CC(Nc1ccc(-n2cccn2)nc1)c1ccco1 +COCc1noc(CCNC(=O)c2cc(C)nc3c(C)cccc23)n1 +COc1cccc(CNC(=O)c2ccccc2SC)c1 +COc1cccc(C(CC(=O)Nc2cccnc2)n2cccc2)c1 +Cc1oc(C)c(C(=O)Nc2ccc(Cl)cc2)c1C +OC(COCc1ccco1)CSc1nnc2ccccn12 +Cc1ncc(CNC(=O)C2(c3ccc(C(C)(C)C)cc3)CC2)s1 +CC1Cc2ccccc2N1C(=O)Cn1cc(C(N)=O)c2ccccc21 +COc1ccc(C(=O)N2CCN(C(=O)c3cnc(C)s3)CC2)cc1 +Cc1n[nH]cc1CNC(=O)c1ccc(Cl)cc1F +CC1CN(C(=O)c2ccc(-c3ccccc3F)o2)CC(C)O1 +O=C(CC1OCCc2sccc21)N1CCN(CCO)CC1 +COc1ccc(NC(=O)c2csc(-c3ccncc3)n2)c(OC)c1 +CC(Sc1ccccn1)C(=O)Nc1ccc(F)cc1N +CC(=O)N1CCC(C(=O)Nc2sc3c(c2C#N)CCCCC3)CC1 +COCCOc1ccccc1NCc1ccccc1F +Cc1noc(C2CN(C(=O)Nc3ccc(Cl)cc3)C2)n1 +COCc1c(C(=O)N2CCN(C)CC2C)sc2cccc(F)c12 +O=C(Nc1ccc(-n2nccn2)cc1)NC1CCC(O)CC1 +CC1(C)CN(C(=O)c2cnn(C(C)(C)C)c2C(F)(F)F)CCO1 +COc1cccc(CNC(=O)c2ccc(Br)c(F)c2)c1 +COC(=O)C(C)(C)NC(=O)Cc1ccc(F)cc1F +COC(=O)c1c(-c2ccc(F)c(F)c2)cn2c1SCC2=O +NC(=O)COc1ccc(NC(=O)N(CC2CCCCC2)C2CC2)cc1 +CC(=O)N1CCC2(CC1)Nc1ccc(Cl)cc1C(=O)N2C1CC1 +Cc1cc(C)cc(OCC(=O)Nc2nnn(C)n2)c1 +CCOc1cccc(CNC(=O)CNC(C)=O)c1 +Cc1cc(F)cc2c1N(C(=O)c1ccncc1F)CCC2 +CCS(=O)(=O)c1cccc(NC(=O)NC(C)(CO)C2CC2)c1 +Cn1c(SCC(=O)NC2CCCCNC2=O)nc2ccccc21 +Cc1ccc2nc(COC(=O)Cc3ccc(F)cc3)cc(=O)n2c1 +CC(C)(C)C(=O)N1CCc2ccc(NC(=O)c3ccno3)cc21 +CC(=O)N1CCc2cc(C(=O)N3CCNC(=O)C3C(C)C)ccc21 +COCc1ccc(C(=O)Nc2ccc(C(C)=O)c(C)c2)cc1 +OC(c1ccncc1)c1cccc(Cl)c1Cl +COCCCc1nc(-c2cc(C)n(CC(F)(F)F)c2C)cs1 +Cn1c(C(=O)NCC(=O)NCCn2cccn2)cc2sccc21 +COCC(C)NC(=O)c1cc2ccccc2cc1NC(=O)C1CC1 +O=C(NCC1(O)CCOc2ccccc21)c1cccc(Cl)c1 +CCOc1ccc(Cc2nc(C)c(N)c(C)n2)cc1 +O=C(NCC(=O)N1CCCc2ccccc21)c1ccc[nH]c1=O +Cc1sc(=O)n(CC(=O)Nc2cccnc2-n2cccn2)c1C +C#CC(C)(C)OCC(O)CN1CCN(c2ccccc2)CC1 +CC(C)Cn1c(NCc2ccco2)nc2c1c(=O)[nH]c(=O)n2C +CN(C)C(=O)c1ccc2c(c1)CCCN2CCOc1ccccc1 +Cc1oc(-c2cccc3ccccc23)nc1CN1CCOCC1 +CCOC(=O)C(N)Cc1cccc(Cl)c1Cl +CN(C(=O)c1cc2sccn2c1)c1ccccc1 +Cc1cc(C(=O)Nc2ccc(OC(F)F)c(F)c2)c(C)o1 +CC(=O)Nc1c(C)ccc(NCC(=O)NCCC2CCCCC2)c1C +CC(Cc1cccc(Cl)c1)NC(=O)NCCCC(N)=O +O=C(Nc1ccccc1O)c1cc(N2CCCC2=O)ccc1Cl +COc1ccc(C(O)CN2CCN(C(C)=O)CC2)cc1 +CCCCCNC(=O)Cc1csc(NC(C)=O)n1 +CCCC(C)NC(=O)c1ccc(F)c(NC(C)=O)c1 +CSc1ccc(C(=O)NCCCC(C)C)cc1 +CC(C)(CNC(=O)c1ccccc1S(C)(=O)=O)C(N)=O +CCOC(=O)c1c(C)c(C(=O)N2CCCCC2)c(C)n1C +NC(=O)c1cccc(CNc2cccc(Br)c2)c1 +CCOC(=O)c1c(C)[nH]c(CCC(=O)NC)c1C +CCOC(=O)c1c(C2CC2)csc1NC(=O)c1ccnc(F)c1 +Cc1ccccc1N1CCN(C(=O)C(O)CC(C)C)CC1=O +CC(CO)C(C)NC(=O)NCc1ccc(C(=O)N(C)C)cc1 +O=C(NCCOc1ccc(F)c(F)c1)NC1CCCCNC1=O +Cc1cccc(N(C)C(=O)CCn2nnc3ccccc3c2=O)c1C +Cc1nc(C)c(CCNC(=O)CCc2ccsc2)s1 +CC(C)C(=O)Nc1ccc(C(=O)N(C)C(C)c2ccncc2)cc1 +Cc1nc2cc(NC(=O)Nc3cnc4c(c3)c(C)nn4C)ccc2o1 +O=C(c1ccccn1)c1c(Cl)cccc1Cl +COc1ccc(F)c(NC(=O)C2CC3CCC2C3)c1 +Nc1nonc1CC(=O)Nc1cccc(Cl)c1 +Cc1cc(N2CCC(n3ccc(C(F)(F)F)n3)CC2)ncn1 +O=C(CCC(=O)c1cccs1)OC1CCCC1 +COc1ccc(NC(=O)N2CCCC(C)C2CO)cc1OC +CCN(CC)C(=O)c1oc2ccccc2c1NC(=O)c1ccco1 +CC(C)Cn1nnnc1SCCC(=O)Nc1cccc(Cl)c1 +CC(NC(=O)NCc1ccccn1)c1cccc(Br)c1 +Cc1ccc(CCCC(=O)N(CC(N)=O)C2CCCC2)cc1 +Cc1cccc(CNc2cccc(S(=O)(=O)NC3CC3)c2C)c1 +CC(Sc1ccccn1)C(=O)NCCn1cccc1 +CC(C(=O)Nc1ccccc1)N1CCN(C(=O)C2CC2)CC1 +COCCCNC(=O)C(C)N1CCCC(NC(C)=O)C1 +NS(=O)(=O)C1CCN(Cc2ccc(F)c(Br)c2)C1 +Cc1nc2ccccc2c(=O)n1Cc1noc(C=Cc2ccccc2)n1 +CN(C(=O)c1cc(-c2cccs2)on1)C1(C#N)CCC1 +Cc1n[nH]cc1NS(=O)(=O)c1ccc(C(F)(F)F)cc1Cl +O=C(c1ccc(OCc2cscn2)cc1)N1CCN(CCO)CC1 +COc1ccc(S(=O)(=O)NC(=O)c2c(C)noc2C)cc1 +CCC(=O)Nc1cccc(NS(=O)(=O)c2ccccc2)c1 +O=C(Nc1ccc(F)cc1F)c1cccc(NC(=O)c2ccco2)c1 +COc1ccc2cc(C(=O)OCc3nccs3)[nH]c2c1 +Nc1c(NCc2ccccc2)ncnc1NCc1ccc(F)cc1 +O=C(c1ccc[nH]c1=O)N1CC(c2nc(-c3ccco3)no2)C1 +C=CCNC(=O)CCOc1ccc(Cl)c(Cl)c1 +COc1ccc(C(C)Nc2cnn(C)c(=O)c2Cl)cc1OC +CCCC1NC(=O)C2CN(CCCc3ccccc3)CCN2C1=O +CC1CCCC(N(C)C(=O)Nc2cc(-n3cnnn3)ccc2F)C1 +CCCC(=O)Nc1ccc2nc(C)n(-c3ccccc3)c(=O)c2c1 +CCNC(=O)NC1CCC(OC(=O)COc2ccccc2C)CC1 +N#CCc1ccc(OCc2cccc(NC(=O)C3CCCO3)c2)cc1 +O=C(c1cc2ccccc2oc1=O)N1CCC(c2cccs2)CC1 +CN(C)C(C(=O)NCC(=O)NC1CC1)c1ccccc1F +O=c1oc2cccnc2n1CCSc1nnc(C2CC2)s1 +CCCN(Cc1ccccc1)C(=O)c1cc(C)no1 +CCNC(=O)NCc1ccc(S(=O)(=O)N(C)C)s1 +Cc1nn(C)c(C)c1C1COCCN1C(=O)c1sccc1C#N +O=C(Nc1ccc(S(=O)(=O)C2CCCC2)cc1)C1CCOCC1 +O=C(NCC(=O)N1CCCC1)c1cccnc1OCC(F)F +CC(=O)N1CCOC(CNC(=O)c2cccc(CCC(C)(C)O)c2)C1 +CC(C)(C)OC(=O)CNc1ccc2nnc(C(F)(F)F)n2n1 +CC(=O)N(Cc1ccc(C(C)C)cc1)c1cccc(N)c1 +CCc1noc(-c2ccc(CCNC(=O)NC3CC3)cc2)n1 +CN(C)C(=O)N1CCN(C(=O)Nc2ccc(OC(F)F)cc2)CC1 +CCOC(=O)CCn1[nH]c(=O)c(Cl)c(Cl)c1=O +CCn1cc(CCC(=O)Nc2cnn(C)c2C)c(C)n1 +CCC(C)(CNC(=O)c1cnc2ccccn2c1=O)N1CCOCC1 +Cc1ccccc1-n1nnc(C(=O)Nc2ccc(Cl)cc2)c1N +CC(C)(C)NC(=O)CSc1n[nH]c(C=Cc2ccc(F)cc2)n1 +COc1cccc(OCC(=O)NCc2cccc(C(N)=O)c2)c1 +CCn1cc(C(=O)N(CC(N)=O)C(C)C)c(C(C)C)n1 +CC(C)OCCS(=O)(=O)N1CCC(c2ccccc2F)C1 +C=CCn1c(C(C)NC(=O)CC)nc2ccccc21 +O=C1CCCN1Cc1cccc(C(=O)N2CCCC2)c1 +Cc1cc(OCCN2CCC(=O)CC2)cc(C)c1Cl +COC(=O)C1(NS(=O)(=O)N2CCCC(C)C2)CCCC1 +CCC(=O)N1CCC(Nc2cccc(NC(C)=O)c2C)CC1 +Nc1cc(-c2nc(-c3ccccn3)n[nH]2)ccc1Cl +Cc1noc(C23COCC2CN(C(=O)c2ncccn2)C3)n1 +O=C(c1ccccn1)N1CCC(S(=O)(=O)c2ccccc2)C1 +CCC(=O)Nc1ccc(C(=O)N2CC(C)CC(C)C2)cc1 +Cc1ccc(S(=O)CC(=O)NC(C)c2ccccc2Cl)nc1 +O=C1C(Nc2ccc(S(=O)(=O)C3CCCC3)cc2)CCN1C1CC1 +N#CC(CCC(=O)NCc1ccccc1)c1cccc(F)c1 +CCc1ccc(-c2cc(=O)[nH]c(COC)n2)cc1N +Cc1cccc2nc(-c3cccc(NC(=O)C(C)C)c3)cn12 +O=C(NCC(O)COc1ccc(F)cc1)c1cnc2ccccc2n1 +CCn1ccc(C(=O)N2CCc3nc(N(C)C)[nH]c(=O)c3CC2)n1 +COCCN(Cc1ccsc1)C(=O)c1cccc(F)c1 +Cc1cc2[nH]c(=O)[nH]c2cc1NCc1ccccn1 +Nc1ccc(OCC(=O)N2CCc3ccccc3C2)c(F)c1 +COc1cccc(CC(=O)Nc2ccc(OC)cc2OC)c1 +COC(=O)c1c(NC(=O)c2ccccn2)c(C)nn1C +CCn1c(SCc2nncn2C)nnc1-c1ccccc1C +Cc1c(-c2ccccc2)nc2ccccc2c1C(=O)N1CCN(C)CC1 +CCOc1c(Cl)cccc1NC(=O)c1cnn(CC)c1 +O=C(NCCc1nc(-c2cccnc2)n[nH]1)c1ccc2c(c1)CCO2 +COCCOC(=O)c1nn(-c2ccccc2)c(=O)c2ccccc12 +O=C(NCc1ccccn1)c1cc2c([nH]c1=O)CCCC2 +Cc1nc(CN2CCN(C(=O)c3cc(Cl)c[nH]3)CC2)cs1 +CC1CCCCN1c1cc(N)n(-c2ccc(Cl)cc2)n1 +O=C(Cc1ccc2c(c1)CCCC2)Nc1cccnc1 +C=C(C)COc1ccc(C(=O)N2CCNC(=O)C2)cc1 +CCOC(=O)COc1ccc2cc(C(C)=O)c(=O)oc2c1 +CCOC(=O)c1nc2cc(C(F)(F)F)ccn2c1N +CCCNC(=O)NCc1cccc(Cn2ccnc2C)c1 +CNC(=O)c1ccc(Cl)cc1NCC(=O)NCc1ccccc1C +Cc1cc(C(=O)Nc2ccccc2C(N)=O)cc(C)c1OC(F)F +COc1ccc(Cn2ccnc2SCCO)cc1OC +Cn1nccc1CNC(=O)C1(c2ccccc2)CCOCC1 +O=C(NCc1ccoc1)c1cn(-c2ccccc2)nn1 +Cc1ccc2cc(C(=O)N3CCCC(NS(C)(=O)=O)C3)[nH]c2c1 +Cc1cc(N)c(N2CCCC2)c(Br)c1 +NC(=O)c1ccc(CNC(=O)NCC2CN3CCCCC3CO2)cc1 +CC(Cc1ccco1)NC(=O)C(C)NC(=O)CC1CCCCC1 +CS(=O)(=O)NCC1CCCCN1C(=O)c1cnccn1 +CCOC(=O)Cc1nnc(-c2cc(OC)cc(OC)c2)o1 +CC(NS(=O)(=O)c1ccc(Cl)c(C#N)c1)c1cccnc1 +CC(C)CN1C(=O)C2(CCCC2)NC1c1cccnc1 +O=S1(=O)CCN(Cc2cccnc2)c2c(F)nc(F)c(F)c21 +O=C(NCc1ccccn1)c1ccc(Cl)cc1N1CCCC1=O +COC(=O)c1nonc1NCC=Cc1ccccc1 +Cc1ccc(Nc2oc3cc(=O)ccc-3cc2C(N)=O)cc1 +CCC(=O)Nc1ccc(S(=O)(=O)C(F)F)cc1 +O=C(NCc1nc2ccccc2[nH]1)c1cc(-c2ccccc2)n[nH]1 +O=C(CSc1ncnn1-c1ccccc1)Nc1ccncc1 +CCc1nc(C)sc1CNC(=O)c1c[nH]nc1C1CCCCC1 +COc1ccc(CCC(=O)N2CCN(CC(C)O)CC2)cc1F +N#Cc1ccc(OCC(=O)N2CCCSc3ccccc32)cc1 +Cc1ccc(N2CCC3(CCN(C(=O)c4ccsc4)CC3)C2)nn1 +CCOC(=O)c1sc2ncn(CC(=O)OC)c(=O)c2c1C +Cc1nc(CN2CCCc3cccc(F)c32)oc1C +Cc1ccc(CC(=O)N2CCC(NC(=O)c3ccccc3)CC2)cc1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2cccc(C(F)(F)F)c2)n1 +COCCN(Cc1cccnc1)c1nc2c(s1)c(C)nn2C +CCN(Cc1ccc(OC)cc1OC)CC(C)C#N +COc1ccc(C)cc1NCc1ccc(NC(C)=O)cc1 +COc1ccnc(NC(=O)c2nnn(-c3ccc(C)cc3)c2C2CC2)c1 +COc1ccc(NC(=O)c2cccc3[nH]ccc23)c(OC)c1 +CCN(CC1CCOC1)C(=O)C(C)Sc1ccccn1 +Cc1cc(C(C)(O)CNC(=O)Nc2cc(F)c(F)cc2F)c(C)o1 +COCCCn1c(-c2ccc(OC)cc2)ccc(CO)c1=O +COc1cccc(OC)c1COC(=O)c1ccc2ccccc2n1 +O=C(NCC1CC1)C1CC2CN(Cc3ccc(F)cc3)CC1O2 +CC(=O)N1CCCC1C(=O)NCc1cccc(OC(F)F)c1 +O=C(NCCn1ncccc1=O)c1ccc(-c2ccccc2)cc1 +CCC1CNc2cc(S(=O)(=O)N3CCNCC3)ccc2O1 +CC1CC1C(=O)NCC(c1c(F)cccc1F)N(C)C +COC(=O)c1cccc(CC(=O)Nc2cc(C#N)cn2C(C)(C)C)c1 +O=C(COc1ccc(Br)cc1Cl)NCCCO +COCCOCC(=O)NC(C)c1ccc(Cl)c(Cl)c1 +Cc1cc(NC(=O)Cc2ccc(F)cc2F)no1 +COCc1cc(=O)[nH]c(Nc2ccccc2Br)n1 +Cc1n[nH]c2ncc(C(=O)N3CCN(C)CC3)cc12 +Cc1ccccc1C1(C(=O)NCc2nccs2)CCOCC1 +CCCn1c(C)c(C(=O)Nc2ccncc2)c2cc(OC)ccc21 +O=C(NCCc1cccc(O)c1)c1n[nH]c2ccccc12 +CCCOC(=O)C(C)n1cc(CO)c2ccccc21 +O=C1CCc2ccc(NC(=O)NC3Cc4ccccc4C3)cc2N1 +C=CCOc1ccc(C(=O)Nc2ccccn2)cc1OC +Brc1cnc(NCc2ccc[nH]2)nc1 +C=CCN(CC=C)C(=O)Nc1nc(C(F)(F)F)cs1 +Cn1cnc(CNC(=O)Nc2nnc(Cc3ccc(F)cc3)s2)n1 +Cc1nccn1CCCNC(=O)c1ccc2nc(C3CC3)oc2c1 +O=C(CNCc1ccccc1)NCCc1ccccc1 +Cc1ccc2c(c1C)NC(=O)CC2c1ccc(Cl)cc1 +CC(C)n1cnnc1C1CCN(c2ncccc2Cl)CC1 +CC(=O)Nc1ccc(C(=O)N(Cc2ccccc2)C(C)C2CC2)cc1 +Cc1c(NC(=O)CCC2CCCC2)c(=O)n(-c2ccccc2)n1C +COC(=O)c1cc(Cl)ccc1NC(=O)c1ccc(=O)n(C)c1 +CCCc1nc(N2CCC(CCO)CC2)c2cnn(C)c2n1 +CC(C)=CCCC1(C)CCC(=O)N(Cc2ccno2)C1 +CCN1CCN(C(=O)CCCOc2ccccc2)CC1 +CCC1CCC(NC(=O)c2cc3c(C)nn(C)c3s2)CC1 +O=C(Nn1cnnc1)c1cccc2c1C(=O)c1cc(Cl)ccc1-2 +Cc1ccnc(SCC(=O)Nc2ccccc2C)n1 +CNC(CC(=O)OC)C(=O)c1ccc(F)c(C)c1 +COc1ccc(C(=O)NCc2cc(-c3ccccn3)n(C)n2)cc1 +CC1CCN(S(=O)(=O)c2ccc(O)cc2)CC1 +CCOC(=O)CCCSc1nc2ccccc2n1C +CC(C)(CNC(=O)NCCO)c1cccc(Br)c1 +Cc1ccccc1CCC(=O)N1CC(C)C(O)(C2CC2)C1 +CNC(=O)c1cccc(CC2COCCN(C(=O)c3cc[nH]n3)C2)n1 +CCOC(=O)CNC(=O)c1cnc(N2CCOCC2)nc1 +CC(=O)c1c(C(C)=O)c(C)n(-c2ccc(C)cc2N)c1C +CC(C)(C)n1cc(C#N)cc1NC(=O)c1cccc(OC(F)F)c1 +CCOC(=O)CSc1c(C)cnc2c1c(=O)n(C)c(=O)n2C +CCOc1ccccc1NC(=O)N1CCCC1C(=O)NC(C)C +O=C(NCCCn1ncccc1=O)c1csc(-c2ccccc2)n1 +N#CCc1nc(CSc2nc3ccccc3o2)cs1 +O=C(Cc1ccccc1F)N1CCN(C(=O)c2ccc(F)cc2)CC1 +O=C(Cc1ccc(O)cc1)N1CCCC(c2nnc3ccccn23)C1 +O=C(c1ccc(F)cc1F)N1CCCC1c1nc(C2CC2)no1 +O=C(c1nc2c(s1)CCN(Cc1cccs1)CC2)N1CCCC1 +O=C(Oc1ccc2c(c1)OCO2)c1cncc(Br)c1 +O=C1OC(C(=O)Nc2ccc(Br)cc2)Cc2ccccc21 +CSc1ccc2c(c1)CCN(C(=O)Cn1ccccc1=O)C2 +COc1ccc(OC)c(-c2nc(C(C)=O)c(C)o2)c1 +COc1cc2[nH]c(=NC(=O)c3cccc4c[nH]nc34)[nH]c2cc1OC +Cc1sc(C(=O)N2CCC(C(C)(C)C)CC2)cc1N +CC(C)c1nnc2n1CC(NC(=O)CC1CCCCC1)CC2 +CC(CC#N)N(C)C(=O)c1ccn(-c2ccccc2F)n1 +CC1Cc2ccccc2N1C(=O)NC1CCN(S(C)(=O)=O)CC1 +NC(=O)c1ccc(N2CCCC2)c(NCC(=O)NC2CC2)c1 +NC(=O)NCC1CCCCN1C(=O)Cc1cccc2ccccc12 +COCCCN(C)C(=O)Nc1cccc(Cl)c1OC +O=C(CC1Oc2ccccc2NC1=O)NC1CCCCC1 +COC(=O)c1cccc(CCNC(=O)Cn2ccnn2)c1 +NC(=O)Cc1ccc(NC(=O)CCC2CCCC2)cc1 +COC(=O)CNC(=O)CC12CC3CC(CC(C3)C1)C2 +CCc1noc(CC)c1CNC(=O)C1COc2cc(OC)ccc2C1 +O=c1c2ccc(Cl)cc2ncn1Cc1noc(-c2cccs2)n1 +O=c1c2ccccc2nc(SCCCO)n1C1CCCC1 +Nc1nccnc1C(=O)NCC(=O)NCC(F)(F)F +Cc1ccc(C(O)C2NCCc3ccc4c(c32)CCO4)cc1 +CC(C)(C)C(=O)NCCn1nc(-c2ccco2)ccc1=O +Cc1oc2ncn(C)c(=O)c2c1C(=O)N1CCc2sccc2C1C +O=C(NCc1ccc(F)cc1)C1COc2ccc(F)cc2C1 +CC(=O)Nc1ccc(Cl)c(C(=O)NCCCCc2ccccn2)c1 +Cc1cc(CNc2cnn(CC3CCCO3)c2)ccc1F +CNC(=O)c1ccc(N)c(OCC(=O)Nc2nccs2)c1 +O=C(NCc1ccncc1)c1cccc(Br)c1O +COC1CCCCC1Nc1ccc(S(C)(=O)=O)nc1 +Cc1ccc(CN2CCOC(c3ccccc3F)C2)s1 +COC(=O)c1ccc(F)c(S(=O)(=O)N(C(C)C)C2CCC2)c1 +Cc1ccc(F)c(C(=O)NCCCc2cn[nH]c2C)c1 +Cc1cc(CNC(=O)NC(C)C(=O)N2CCCCC2C)no1 +CC1CC1C(=O)N1CCN(C(=O)CCc2nc(C3CC3)no2)CC1 +COc1ccc(S(=O)(=O)N2CCCCCC2)cc1F +C=CCN(Cc1cccc(OC)c1)C(=O)c1sc(NC)nc1C +COc1ccc(NC(=O)c2cc(F)cc3[nH]cnc23)c(OC)c1 +CC(C)(C)OC(=O)Nc1ccc(F)cc1NC(=O)c1cccnc1 +COC(=O)c1c(Cc2ccccc2Cl)c[nH]c1C +O=C(Nc1cccc(-c2nccs2)c1)N1CCC(CO)CC1 +O=C(CSc1ccccc1F)Nc1cccc2cn[nH]c12 +O=C(Cc1cnn(-c2ccccc2)c1)Nc1ccc(-n2ccnc2)cc1 +CC(c1nc(-c2cccs2)no1)N(C)Cc1cnn(C)c1 +COc1cc2c(=O)c(-c3ccc(OC)c(OC)c3)coc2cc1O +CC(NC(=O)c1cc(Cl)cc(Cl)c1)C1CCCO1 +Cn1cnc(CNC(=O)C2CCCN2c2ncnc3sccc23)n1 +COC(=O)c1cc(-c2ccc(-n3cccn3)cc2)c[nH]1 +CC1CCC(NC(=O)NCCCOCC2CCOCC2)C(C)C1 +Cc1cc2nnc(SCC(=O)N3CCCCC3C)n2c(N)n1 +CCn1cnnc1CNc1ncnc2ccccc12 +CC(C)(C)c1csc(NC(=O)Cc2cn3ccsc3n2)n1 +O=C(Nc1cccc(F)c1)N1CCC2(CC1)OCCO2 +COCCCNc1nc(C(F)(F)F)cc(=O)[nH]1 +COC(=O)c1ccc(S(=O)(=O)Nc2ccc(-n3nccn3)cc2)o1 +COc1ccccc1-c1noc(CCC(=O)NC(C)C)n1 +C#CCN1CCN(CC(=O)N(C)C2(C#N)CCCCC2)CC1 +O=C(Cc1cccc2ccccc12)N1CCN(Cc2ccccn2)CC1 +O=C(CCn1ncc2ccc(Cl)cc21)N1CCOCC1 +CC1CCC(C)N(C(=O)Nc2ccc(CC(=O)NC(C)C)cc2)C1 +Cc1nn(C)c(C)c1NC(=O)C(C)n1nc(C(F)F)c(Cl)c1C +Cc1ccccc1OCCNS(=O)(=O)c1ccc(N)cc1 +Cc1ccc2cccc(NC(=O)Cc3ccc(F)cc3F)c2n1 +COc1ccc(C(C)=O)cc1CC(=O)Oc1ccc(C)cc1 +CCc1noc(CC)c1CNC(=O)C1CCCN1C(=O)c1ccco1 +Cc1ccoc1C(=O)Nc1scc(C2CCCCC2)c1C(N)=O +Cc1nc(CNC(=O)Nc2nc3ccccc3s2)c2ccccn12 +COc1ccc2nc(N3CC(C(=O)N4CCNC(=O)C4)C3)sc2c1 +O=C(c1ccc2[nH]cnc2c1)N1CCN(Cc2ccccc2F)CC1 +CCc1nnc(NC(=O)Cn2nnc(-c3ccc(C)cc3)n2)s1 +CCC(CC)CNC(=O)NCCc1c[nH]c2ccc(F)cc12 +O=C(c1cc[nH]c(=O)c1)N1CCOC2(CCCC2)C1 +CC(C)c1ccc(S(=O)(=O)N2CCC(O)CC2)cc1 +O=C(CCc1nc(-c2ccncc2)no1)Oc1ccc(Cl)cc1 +COc1cccc(-c2cc(-n3cccn3)ncn2)c1 +CS(=O)(=O)c1ccc(CNC(=O)CCc2ccco2)cc1 +Cc1csc(CNc2ccc(C(=O)N3CCc4ccccc43)cc2)n1 +COc1ccc2nc(NC(=O)CN3CC(C)OC(C)C3)sc2c1 +CC(NC(=O)C(C)(C)NC(=O)c1cccs1)c1ncn[nH]1 +Cc1cc(S(=O)(=O)N(C)C)cnc1NC(C)C +Cc1cccnc1C(Cc1ccsc1)NC(=O)Cn1ccnc1 +COc1ccccc1CN(C)C(=O)Cn1cc(Br)cn1 +C=CCNC(=O)CNc1ccc(C(=O)NCC)cc1 +Cc1cc(C2CCCN(C(=O)c3cccc4c3OCO4)C2)n[nH]1 +CCOC(=O)c1cnc2nc(-c3ccccc3)nn2c1COC +CCc1cc(-c2cc(-c3ccc(O)cc3C)nc(N)c2C#N)[nH]n1 +Cc1ccc(-n2nnc(-c3ccccn3)c2N)cc1C +O=C(Nc1ccc(N2CCN(C3CCCC3)C2=O)nc1)C1CCOC1 +CCN(Cc1ccccc1)C(=O)CCS(=O)(=O)N1CCNCC1 +CCn1ncc(-c2cc(C(F)F)n3nc(C)c(Cl)c3n2)c1C +CCCn1nc(C(=O)N2CC=C(c3ccccc3)CC2)ccc1=O +COc1ccc(C(=O)N2CCN(C(=O)c3ccoc3)CC2)cc1 +CCOc1ccc(C(=O)N(C)CCc2ccc(F)cc2)cc1 +CCCOCc1ccccc1CNc1nccnc1C#N +CCCC(=O)N1CCCC(C(=O)Nc2cc(C)ccc2F)C1 +CCNc1nc(SC(C)C)nc(N2CCOCC2)n1 +COc1ccccc1-c1cc(Cn2cnc3ccccc32)on1 +CNC(=O)CN1C(=O)CCC12CCCN(C(=O)C1CCCO1)C2 +Cc1ccc(C(O)CNC(C)c2cccnc2)cc1 +Cc1nnc2n1CC(NC(=O)Cc1coc(-c3ccccc3)n1)CC2 +CN(C)C(=O)N1CCC(C(=O)Nc2cc(Cl)cc(Cl)c2)CC1 +CCN(CC(=O)NC(C)(C)C)C(=O)C1COc2ccc(F)cc2C1 +COc1ccc2c(c1)CC(NC(=O)NCc1cccc(F)c1)CO2 +C=CCNc1nc(-c2ccccn2)nnc1-c1ccccc1 +CC(C)C(NC(=O)c1ccccc1)C(=O)Nc1ccccc1C#N +CC(C)c1cc(C(=O)NCc2cccs2)no1 +COc1cccc(CNC(=O)CC2COc3ccccc3NC2=O)c1 +COc1ccccc1CC(C)NC(=O)c1cc(-c2cccs2)no1 +CC1CCCN(c2nnc(SCC(N)=O)n2Cc2ccco2)C1 +COC(=O)c1ccoc1CSc1nc2cc(F)c(F)cc2[nH]1 +CCCN1C(=O)C(CC(=O)N2CCCCCC2)Sc2ncccc21 +CSc1ccc(NCc2nnc(-c3ccccc3)o2)cc1 +N#CC(N)CCOc1c(F)c(F)c(F)c(F)c1F +CCCOC1CCCN(C(=O)Nc2cc(C)cc3cccnc23)CC1 +CCn1c(-c2cccs2)nnc1S(=O)(=O)CC(=O)NC1CC1 +O=C(NC1CC1)c1cc(CN2CCOCC2)on1 +COc1cc(C2NC(=O)c3cccc(C)c3N2)ccc1SC +Cc1cccn2c(=O)cc(CSc3nnc4n3CCCCC4)nc12 +Cn1c(N2CCN(C(=O)c3ccccc3F)CC2)cc(=O)n(C)c1=O +CC(C)n1ccc(=O)nc1SCC1CCCCC1 +COCCCCn1c2c(sc1=O)CCCCC2 +Cc1cncnc1N1CCN(C(=O)Nc2ccccc2)CC1 +CC(C)Nc1nnc(SCC(=O)c2c[nH]c3ccccc23)s1 +Nn1cnnc1SCC(=O)N(C1CCCCC1)C1CCCCC1 +COc1ccc(Cl)cc1NC(=O)COc1cc(C)on1 +O=C(CCn1ncc2cc(Cl)ccc21)N1CCCC1 +O=C(Cn1c(CO)nc2ccccc21)N1CCCCC1 +c1cc(CN2CCN(Cc3cnc(C4CCC4)s3)CC2)ccn1 +COc1cccc(C2CC2C(=O)OCc2ccoc2C)c1 +Cc1ccc(-c2nc3cc(C)cnc3n2CCCO)cc1 +Cc1nc(CCNC(=O)Nc2c[nH]c(=O)c(C)c2)sc1C +Cc1nnc(NC(=O)CNC(=O)c2ccc(=O)[nH]c2)s1 +Cc1ccc(C(=O)N2CCCN(S(C)(=O)=O)CC2)c(O)c1C +CCCn1c(C)nnc1SCc1ccc(C#N)cc1 +Cc1ccc(CNC(=O)Cc2sc(C)nc2-c2cccs2)cc1 +COc1cc(-c2noc(-c3ccc(Cn4cccn4)cc3)n2)ccn1 +O=C(Nc1ccc(OCC(F)(F)F)cc1)c1ccc[nH]1 +CCC(CNC(=O)C1(C#N)CCCC1)NC(=O)C1(C#N)CCCC1 +CC1CC1c1ccc(CN(C)S(=O)(=O)c2ccc(F)cc2)o1 +C#Cc1cccc(N(CC(=O)NC)S(=O)(=O)c2cc(C)oc2C)c1 +CCOc1cc(NC(=O)c2cccc(C)c2)c(OCC)cc1N +Cc1ccccc1NC(=O)Nc1nnc(N2CCCC2)s1 +O=C(Nc1ccncc1)c1cc2cc(Br)ccc2[nH]1 +CCOc1ccc2nc(NC(=O)Cc3c(C)noc3C)sc2c1 +CC(C)Nc1nc2c(c(=O)n(C)c(=O)n2C)n1C +O=C(Nc1cccc(Cl)c1)N1CC(c2nc(-c3ccco3)no2)C1 +COC(=O)C(C)NC(=O)C1CCCCN1C(=O)OC(C)(C)C +O=C(c1cc2ncccn2n1)N1CC=C(c2ccc(F)cc2)CC1 +COCC(=O)Nc1ccccc1-c1nc(-c2ccccc2)n[nH]1 +O=C(c1c[nH]c(=O)c(Br)c1)N1CCOC2CCCCC21 +CC1Oc2c(C(=O)Nc3ccc(-n4cnnn4)cc3)cccc2C1C +CCNc1ncc(S(=O)(=O)N(CC)CC)cn1 +Cn1cc(C(=O)Nc2nc3ccccc3[nH]2)c(C(C)(C)C)n1 +Cc1ccc(N2CCCN(C(=O)c3ccc(C#N)c(C)n3)CC2)nn1 +O=C1CCC2(CCN(C(=O)C3CCCO3)CC2)CN1Cc1ccoc1 +CCC(Sc1nnnn1Cc1ccco1)C(=O)c1ccccc1 +Cc1c(C(=O)NC2CCCCC2)nc2cc(Cl)ccn12 +COCCCNc1ncnc(Nc2cccc(C)c2)c1N +Cn1c(SCC(=O)NC2CCCCC2)nnc1-c1ccncc1 +O=C(c1cc(Cl)ccc1F)N1CCN(C2CCCC2O)CC1 +C=CCNC(=O)c1cc(C2CC2)nc2c1c(C)nn2C +COc1ccc2nnc(CCC(=O)Nc3ccccn3)n2n1 +O=C(CCN1CCOC1=O)NCCc1cccs1 +O=C(CN1CCN(CCOc2ccc(F)cc2)CC1)N1CCCCC1 +CC(=O)Nc1nc2c(s1)CN(C(=O)NC(C)(C)C)CC2 +CCc1c(C)sc(NC(=O)c2ccccc2S(C)(=O)=O)c1C#N +CC1CCC(NS(=O)(=O)CC(=O)N2CCCC(C)CC2)CC1 +CCN(CC(=O)NCc1nc(C)cs1)c1ccccc1 +COc1ccc(OC)c(COC(=O)C(N)C(C)C)c1 +COc1cc2c(cc1OC)CCN(C(=O)c1ccc[nH]c1=O)CC2 +O=C1CCN(C(=O)Cc2cccc(Cl)c2)CCN1 +Cc1nc2c(N(C)Cc3noc4c3CCCC4)ncnc2o1 +CC(Oc1ccc(C#N)cc1)C(=O)NCC(O)c1c(F)cccc1F +COC(C)(C)c1noc(CN2C(=O)CCc3ccccc32)n1 +Fc1cccc(Oc2ccc3nnc(C(F)(F)F)n3n2)c1 +N#Cc1ccccc1Oc1ccc(S(=O)(=O)N2CCCC2)cn1 +CCOC(=O)Cn1nc(C#N)cc1-c1ccc(OC)cc1 +COc1ccc(F)cc1NC(=O)C1CC1(Cl)Cl +CC(=O)Nc1cccc(CNC(=O)Nc2cnccc2C)c1 +CC(CC#N)N1CCN(Cc2csc(C(C)(C)C)n2)CC1 +CCn1ccc2c(cnc3nc(COC)nn32)c1=O +CCNC(=O)c1ccc2c(c1)CCN2C(=O)C1CC1 +Cc1cc(F)ccc1CNc1ncccc1Cl +CCc1nc2n(n1)CCCC2NC(=O)NCCc1ccccc1 +COc1ccc(OC)c(C(=O)Nc2nc(-c3ccccn3)cs2)c1 +N#Cc1ccnc(N2CCN(C(=O)c3cccnc3)CC2)c1 +COC(=O)C(NC(=O)c1cccc(-n2nc(C)cc2C)c1)C(C)C +CCc1nnc(NC(=O)CCc2nc(Cc3ccccc3)no2)s1 +COc1ccc(-c2csc3nc(C)c(CC#N)n23)cc1 +O=C(CCNC(=O)c1cccs1)NC1CCCCCC1 +Cc1cc(S(=O)(=O)Nc2ccccc2O)ccc1F +Cc1cccnc1CNC(=O)NCCCc1nc2ccccc2[nH]1 +Cc1ccc(C(=O)OCC(=O)Nc2cc(C)on2)cn1 +O=C(OCC(=O)N1CCOCC1)c1ccc(COc2ccccc2)o1 +Cc1ccc(F)cc1NC(=O)NCC(C(C)C)N1CCOCC1 +CCn1nc(C)c(Cl)c1C(=O)Nc1ccn(Cc2ccccc2)n1 +Cc1cc(NC(=O)c2ccoc2)ccc1-n1cnnn1 +CS(=O)(=O)c1ccc(-c2cc(N3CCCC3)nc(N)n2)cc1 +CC(C)NC(=O)C1CCN(c2ccc(C#N)cc2C(F)(F)F)CC1 +Cc1nc(C(=O)N(C)Cc2c(C)noc2C)cs1 +CN1C(=O)CCC(C(=O)NCc2ccccn2)C1c1cccc(F)c1 +CC(CNC(=O)Nc1ccnn1C1CCCCC1)N1CCOCC1 +CCOc1cccc(NC(=O)NC(C)C(=O)NCc2ccccc2)c1 +CN1CC(NC(=O)N(CCCCO)C2CC2)CCC1=O +Cc1cc2cc(CNC(=O)c3ccco3)ccc2n1C +COc1cc(Cn2nnnc2C)c(OC)cc1Br +CC(C)NC(=O)C1CCN(c2nc3ccccc3n(C)c2=O)CC1 +C#CCOC(=O)CN1CC2CC(C1)c1cccc(=O)n1C2 +C(#CCSc1ncccn1)CSc1ncccn1 +N#Cc1ccc(C(=O)NCC#CCOc2ccc3c(c2)OCO3)cc1 +Cc1cc(C(F)(F)F)nn1C(C)C(=O)NC1CCCC1 +CN(CC(=O)NCC1(C(N)=O)CCOCC1)c1ccc(Cl)cn1 +CN(C)C(=O)c1ccccc1NC(=O)C1Cc2ccccc2C(=O)O1 +Cc1cc(C)cc(NC(=O)CNc2ccc(C)c(-n3cnnn3)c2)c1 +COc1ccc(F)c(NC(=O)c2ccc(NC(C)=O)cc2)c1 +O=C1CCN(Cc2ccc(F)cc2F)c2ccc(F)cc2N1 +C=CCn1nnnc1SCC(O)CN1CCOCC1 +O=C(Oc1ccc(NC(=O)C2CC2)cc1)c1cnccn1 +COCC(=O)NCc1ccc(S(C)(=O)=O)cc1 +O=C(CCn1ncc(=O)c2ccccc21)Nc1ccc2c(c1)CC(=O)N2 +Cc1nc(NC(=O)C(C)OC(=O)c2cccc(O)c2)sc1C +Cc1ccn2c(=NC(=O)Cc3cccc(OC(C)C)c3)[nH]nc2c1 +COc1ccc2cc3c(N)nn(C(=O)c4ccccc4F)c3nc2c1 +O=C(CNc1cccc(F)c1)Nc1ccc2c(c1)OCO2 +O=C(NCc1cccc2ccccc12)NC(CCO)c1ccccc1 +COc1ccc(NC(=O)Cc2csc3nc(C)cn23)cc1 +COc1ccccc1C(=O)N1CCC(c2nnc(C(C)C)o2)CC1 +Cc1cc(NC(=O)C(C)NC(=O)c2ccccc2)ccn1 +CC(C)C(=O)NCc1nnnn1-c1ccc(F)c(F)c1 +COc1cccc(C2c3cccn3CCN2CC(=O)NCC(C)C)c1 +N#Cc1cccc(C(=O)Nc2ccc(NC(=O)C3CC3)cc2)c1 +O=C(NCCOc1cccnc1)c1ccc2c(c1)OCO2 +C#CCn1c(CCNC(=O)Cc2ccccc2C)nc2ccccc21 +CC(=O)Nc1cccc(CNC(=O)c2cnn(-c3ccncc3)c2C)c1 +CC1CN(C(=O)NC(C)c2ccc(-n3ccnc3)cc2)c2ccccc21 +COc1ccc(S(=O)(=O)N2CCC(C#N)CC2)cc1Cl +CC1CCC(C(N)=O)CN1C(=O)c1ccc(C(=O)NC(C)(C)C)cc1 +CCCc1nc2ccccc2n1CC(=O)Nc1c(C)cccc1C +CC(C)(C)c1cccc(OC(=O)Cn2nc3ccccn3c2=O)c1 +CC=CCOC(=O)c1cc(NC(C)=O)ccc1F +CCc1noc(C(C)Sc2nc(C)nc(C)c2C#N)n1 +Cc1ccc(NC(=O)N2CCC3(CC2)OCCO3)cc1 +CC(=O)NC1CC2CCCC(C1)N2C(=O)Nc1cccc(Cl)c1 +CN(Cc1ncnn1C)C(=O)c1ccc(-c2cscn2)cc1 +CC(C)N(Cc1cnn(C)c1)C(=O)C1CC1c1ccc(F)cc1F +O=C(NCc1ccnc(-n2cccn2)c1)C1(c2ccc(F)cc2)CC1 +CC(C)c1cccc2c(C#N)c3c(nc12)CCN(C)C3 +CC(C)CNc1nnc(-c2ccc(=O)n(CC(C)C)n2)s1 +COc1ccnc(N2CCN(S(=O)(=O)c3cccc(C)c3)CC2)n1 +COCCn1cc(NC(=O)CCC(C)C)ccc1=O +CCNc1nc(-c2scnc2C(C)C)cs1 +COC(=O)CSc1nnc(-c2ccccc2F)n1C +Cc1nc(C)c(C(=O)N2CCC(Oc3cnccn3)CC2)s1 +O=C(NC1CCN(C(=O)Cc2ccc(O)cc2)CC1)c1ccccc1 +CCN(C)C(=O)c1cccc(C(=O)N(C)CCc2ccccc2)c1 +Cc1ccc(Cl)cc1NC(=O)CSc1c(C)n[nH]c1C +Cc1ccc(NC(=O)C2CC=CC2)cc1OCC(F)F +Cc1nc(N(C)C)sc1CNc1cnn(-c2ccccc2)c1 +CCNC(=O)CN(C)C(=O)c1cccc(C(N)=O)c1 +CC(=O)Nc1nnc(-c2cccc(S(C)(=O)=O)c2)o1 +COc1ccccc1CC(=O)Nc1nc(C)cs1 +CC(C)c1noc(CCCC(=O)N(C)Cc2cccs2)n1 +CCc1ccc(C(C)NC(=O)c2ccc3c(c2)OCC(=O)N3)cc1 +c1ccc(-n2nnnc2Sc2ncnc3c2oc2ccccc23)cc1 +COC(=O)Cn1nc(-c2ccc(Br)cc2)ccc1=O +CC(CCCO)NC(=O)Nc1ccc(-c2ncc(C(C)C)o2)cc1 +N#CCCN(C(=O)c1ccc(Cl)cc1)C1CCCC1 +CSc1ccc(CNc2ncnc3sccc23)cc1 +Cc1cc(N)cc(C)c1NC(=O)COc1ccc(Cl)cc1Cl +CS(=O)(=O)NCCNC(=O)c1cc(F)ccc1Br +CC(C)(C)OC(=O)N1CCC(Oc2cccc(F)c2N)CC1 +Nc1cccc(CCC(=O)NCc2cccnc2)c1 +COC(=O)C(C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(C)=O +Cc1csc(CCNC(=O)NCCOc2ccc(F)cc2F)n1 +C=CCNC(=O)CSc1nc(-c2ccc(OC)cc2)n[nH]1 +O=C(NCCc1nc2ccccc2[nH]1)c1ccc(-c2ccco2)[nH]c1=O +CNc1ccc(C)cc1C(=O)NCc1ccccc1 +CC(=O)c1ccc(CNc2ccnc(C(C)C)n2)nc1C +Cc1ccsc1CN(C(=O)C(C)NC(N)=O)C(C)C +CCC(=O)Nc1ccc(C(=O)Nc2ccccc2C)cc1 +NC(=O)c1nc(S(N)(=O)=O)ccc1OC1CC1 +CC(=O)NCCC(=O)NCCNC(=O)c1ccccc1 +CC(=O)NCC(=O)NCC(=O)N(C)Cc1sccc1C +Nc1ccc2c(c1)CN(c1nc(C3CC3)cs1)C2 +CC1CCCCC1NC(=O)c1cccc(S(C)(=O)=O)c1 +COc1cc(NCc2ccco2)ccc1S(=O)(=O)N1CCCC1 +CCc1ncc(-c2cc(C(=O)N3CCCC3)c3ccc(C)cc3n2)cn1 +CCC(C)NS(=O)(=O)c1c(C)nn(CC)c1C +Cc1ccc(NCc2ccc3c(c2)OCO3)c(O)c1 +Cn1ccnc1SCc1ccc(OC(F)(F)F)cc1 +CCCCOCCC(=O)Nc1c(N)cc(Cl)cc1Cl +COc1ccccc1C(=O)NCCNc1cc(-n2cccn2)ncn1 +CC(C)(C)OC(=O)Nc1cccc2c1OC(CO)C2 +Cc1cc(=O)[nH]c(N2CCCC(c3nc(-c4ccncc4)no3)C2)n1 +COc1ccc(C2(CNS(N)(=O)=O)CCOCC2)cc1 +CCCCN(CC(N)=O)C(=O)c1oc2ccc(F)cc2c1C +Cc1cccc(NC(=O)Cc2ccccc2Cl)n1 +CCC(=O)Oc1ccc(C(=O)N(C)c2ccccc2)cc1 +CN(Cc1ccccc1F)C(=O)c1cc2occc2n1C +CCC(C)n1nccc1NC(=O)C(NC(=O)c1ccccc1)C(C)C +CC(=O)NC(C)C(=O)NC(CN1CCCC1=O)c1ccccc1 +CNC(=O)c1ccc(CNC(=O)NC2CCC(O)CC2)cc1 +Cc1n[nH]c(Sc2cc(Cl)ccc2C#N)n1 +CCNC(=O)c1ccc(C)c(NC(=O)C2(C#N)CCCC2)c1 +O=C(NC(COCc1ccccc1)c1ccccc1)C1COCCO1 +CC(=O)Nc1ccc(C(=O)N(C)Cc2cccnc2)cc1 +c1cc(CNCc2ccc(OC3CCCC3)nc2)ccn1 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1ccc(Cl)cc1 +O=C(Nc1cccc2[nH]ccc12)C1CCCCC1C(=O)N1CCCC1 +COc1ccc(CNC(=O)C2CC3C=CC2C3)cc1OC +CCC1(CC)C2N=C(Cl)C(C#N)C1(C#N)C(=O)N2 +Cc1cc(-n2c(C)cc(C(=O)NCCO)c2C)no1 +Cc1cnn(CC(=O)NCc2cccc(OCC(F)(F)F)c2)c1 +COc1ccc(C(=O)NCC(=O)NC(C)C)cc1OC(F)F +Cc1cc(C(=O)NC(C)c2cccc(C(F)(F)F)c2)n(C)n1 +Cc1cc(N(C)C)cc(C)c1NC(=O)N1CCOCC1C1CC1 +COCCN(C(=O)c1sc2nc(C)nc(C)c2c1C)C1CC1 +CCCOc1ccccc1Oc1ccc(C#N)cn1 +CCN(CC)C(=O)C1CCCN(C(=O)Nc2ccccc2)C1 +Cc1cc(O)ccc1-c1cc(-c2cnn(C)c2C2CC2)c(C#N)c(N)n1 +COC(=O)c1cc(CNc2cnn(Cc3ccc(Cl)cc3)c2)c[nH]1 +COCCOc1ccccc1CN1CCOC(c2cccc(O)c2)C1 +CS(=O)(=O)NC(CO)CC(O)c1ccccc1 +COc1cccc(OCc2nc3ccc(C)nc3o2)c1 +COc1cccc(NC(=O)Nc2cc(N3CCCC3)ncn2)c1 +CCc1ncc(C(=O)N2CCC(C(O)c3ccccc3)CC2)s1 +CC(=O)NC1CCCc2ccc(C(O)c3ccco3)cc21 +O=C(CCCO)N1CCN(C(=O)c2cccnc2)CC1 +COC(=O)c1ccc(OC(=O)c2scnc2C)cc1 +Cc1c(N)cccc1C(=O)N1CCCCC1C(N)=O +O=S(=O)(NC1CCN(c2cccc(F)c2)CC1)c1cccnc1 +COc1ccc(C(=O)CSc2nc3ncccc3[nH]2)cc1 +Cc1nn(-c2nc3c(c(=O)[nH]c(=O)n3C)n2CCC(C)C)c(C)c1C +CC(C)n1nnc(C#N)c1Cc1c[nH]c2ccccc12 +COc1ccc(C(=O)NC(CC(C)C)c2ccccc2)nn1 +CC(C)CC(=O)Nc1ccc2c(c1)sc(=O)n2C +Cc1cc(N2CCN(C(=O)Cc3ccccc3Cl)CC2)nc(N)n1 +COC(=O)CCC(=O)N(Cc1cccc(F)c1)C1CC1 +O=C(CCCC(=O)c1ccc(F)cc1)OC1CCOC1 +Cc1cnn(-c2ccc(C(C)NC(=O)Cc3ccc[nH]3)cc2F)c1 +O=C(NC1CC1c1cccc(Cl)c1)c1cn2cccnc2n1 +CC(C(=O)Nc1cccc(F)c1F)c1cccs1 +CCCn1c(C)nnc1SCC(=O)N(C)Cc1ccco1 +CCC(NC(=O)CCNC(=O)c1ccccc1)c1ccc(Cl)cc1 +COc1cc(C)ccc1OCC(=O)N1CCc2ccc(Cl)cc2C1 +Cc1c(C)n2c3c(=O)n(C)c(=O)n(C)c3nc2n1-c1ccc(O)cc1 +Cc1cccc(NC(=O)c2cncc(Br)c2)c1 +COc1nc2c(cc1C(=O)NCc1ccon1)CCC2 +CCc1oc2ccccc2c1CN(C)C(=O)COC +COCCN(CC(N)=O)S(=O)(=O)c1cc(C)ccc1C +CN(CC(=O)N1CCNCC1)C(=O)c1cnccn1 +Cn1nnc2c1C(COCC1CC1)CN(Cc1nccs1)C2 +CC(=O)NCCNC(=O)c1cc(-c2cccc(Cl)c2)on1 +CCC(C)NC(=O)CCNC(=O)c1cn2cccnc2n1 +O=C1CCN(CCOc2cc(Cl)cc(Cl)c2)CC1 +Cc1cc(NC(=O)NCc2nc(C3CC3)cs2)c2ncccc2c1 +Cc1cccc(OC2CCN(C(=O)c3cc4ccccc4[nH]3)CC2)n1 +COCC1CCCN1C(=O)c1cc(C)nc2c(C)cccc12 +Fc1ccc(OCc2noc(-c3ccco3)n2)c(F)c1 +CC(C(=O)Nc1ncccn1)N1CCN(S(=O)(=O)N(C)C)CC1 +COc1ccccc1OCc1nc(CC(=O)NC2CCCC2)no1 +CC(C)OCCCN1C(=O)CCC1c1c[nH]c2ccccc12 +CC(CO)(NC(=O)Nc1ccc2c(c1)OCO2)C1CC1 +CC(C)CCNC(=O)NC1CCN(S(=O)(=O)C2CC2)CC1 +O=C(CN1CCOC(c2cccc(O)c2)C1)NC1CCCCC1 +CC(C(=O)Nc1ccccc1)c1nc(-c2cccc(N)c2)cs1 +CC1(C(=O)Nc2cccc(C(=O)N3CCCCC3)c2)CCCO1 +Cc1noc2nc(-c3ccccc3)cc(C(=O)NCc3ccco3)c12 +Nc1cc(Cl)ccc1OCc1cn2ccccc2n1 +CC1CCC(C)N1C(=O)c1cc(N2CCCC2=O)ccc1Cl +Nc1c(NCc2ccc(F)cc2)ncnc1NCc1ccc(F)cc1 +O=C(c1ccc(F)c(F)c1)N1CC(c2nc(-c3cccs3)no2)C1 +CCC(CC)C(=O)Nc1nnc(S(=O)(=O)N2CCCC2)s1 +COc1cc(CC(=O)NCc2ccco2)cc(OC)c1OC +Cc1nc(C2CCCN(C(=O)CCN3CCCC3=O)C2)sc1C +Nc1cc(C(=O)Nc2cc(F)ccc2F)ccc1F +CCc1ncc(C(=O)NCCn2nc(C)c(Cl)c2C)cn1 +N#CCCn1cccc(OCCC(=O)N2CCCCC2)c1=O +CC(=O)Nc1ccccc1NC(=O)c1ccccc1Cl +COCCCNC(=O)c1c(NC(=O)C2CC2)sc2c1CCCC2 +Cc1ccc(NC(=O)NCc2ccoc2)c(Cl)c1 +COCCNC(=O)Cn1cc(N)cc1C(=O)OC +COc1ccc(C(=O)Nc2cc(N)ccc2C)cc1Cl +O=C(Cn1cnc2sc3c(c2c1=O)CCC3)Nc1nccs1 +COCCNC(=O)CCn1ncc2ccc(C)cc21 +Nc1cncc(-c2nc(-c3cccc(Br)c3)no2)c1 +c1csc(-c2noc(CN3CCOCC3C3CC3)n2)c1 +CCn1nnc(CO)c1-c1ccc(S(=O)(=O)N(C)C)cc1 +CCc1onc(C)c1C(=O)N1CCC(c2cc(O)nc(N(C)C)n2)C1 +Cc1nc(C2CCCN(C(=O)NCCN(C)c3ccccc3)C2)no1 +O=C(c1ccccc1F)N1CCN(Cc2cnc3ccccn23)CC1 +COC(=O)C(C)NC(=O)c1cccc2c1ccn2C +COc1ncnc2c1CN(Cc1coc(-c3cccs3)n1)CC2 +Cc1ccc(O)c2c1C(C(O)c1ccccc1F)NCC2 +Nc1cc(S(=O)(=O)Nc2cn[nH]c2)ccc1Cl +COc1cccc(OCC(=O)N2CCC(C(N)=O)c3ccccc32)c1 +COCC(C)OC(=O)COc1ccc(C)c(C)c1 +COc1ccccc1NC(=O)COC(=O)C=C(C)C +c1ccc(-c2ccncc2)c(CN2CCOCC2)c1 +Nc1cccc(CC(=O)Nc2ccc(Cl)c(Cl)c2)c1 +Cc1ncc(Cl)c(C(=O)N2CCCC(c3nccs3)C2)n1 +Cn1nnnc1SCC(=O)c1ccc(C#N)cc1 +CC1CN(CC(O)CO)c2cc3c(cc2N1)CCCC3 +CC1(C)OC(=O)c2c1ccnc2NCCC(=O)NCc1ccncc1 +Cc1nc(-c2cccc(NC(=O)NCc3ncn(C)n3)c2)n[nH]1 +Cc1nn(C)c(C)c1CCC(=O)NCCc1nc2ccc(F)cc2[nH]1 +COC(=O)CNC(=O)c1ccccc1-n1cccc1 +CNC(=O)C1CCN(C(=O)c2c(-c3ccc(F)cc3)noc2C)CC1 +O=C(Nc1nnc(Cc2cccc(F)c2)s1)c1ccc(F)nc1 +CCC1CN(C)c2ccccc2CN1C(=O)c1ccc(COC)o1 +COc1cc(OC)c(NC(=O)N2CCCC(C)C2)cc1F +CC(Sc1n[nH]c(=O)n1CC1CCCO1)c1ccccc1 +Cc1ccc(-c2noc(CNC(=O)Cc3ccc(F)cc3)n2)cc1 +Cc1ccc2ncc(C(=O)N(C)Cc3nc(C)cs3)n2c1 +CSc1nsc(NC(=O)CCCNC(=O)c2ccco2)n1 +COC(=O)c1cccc(CC(=O)N(C(C)C)C2CCOCC2)c1 +CC1CN(C(=O)c2ccccc2Nc2ccccc2)CCO1 +O=C(COc1ccccc1F)NCCCc1ccc(O)cc1 +Fc1ccccc1OCCSc1nc(C2CC2)n[nH]1 +COc1ccsc1C(=O)Nc1cn(C)c(=O)cc1C +CCOC(=O)Nc1ccc(NC(=O)c2cc(C3CC3)[nH]n2)cc1 +Cn1cnnc1C1CCCN(C(=O)COc2ccccc2Cl)C1 +O=S(=O)(NCCCO)c1cc(Cl)c(Cl)cc1Cl +CC(C)c1ccc(OCCNC(=O)c2cn3cccnc3n2)cc1 +Cn1cc(C(=O)Nc2ccc(C(F)(F)F)cc2)c(C(F)(F)F)n1 +Cc1cccc(C(CNC(=O)NC(C)C(C)CO)N2CCOCC2)c1 +Cc1nc(C)c(C(=O)N2CCC(OCc3ccccc3C)CC2)s1 +CCCCC1C=CCN1C(=O)Cn1c(=O)cnc2ccccc21 +CNC(=O)c1ccc(NS(=O)(=O)c2cc(C)ccc2C)cc1 +CC(C)c1noc(CCNC(=O)N2CCCCC2c2cn[nH]c2)n1 +O=S(=O)(c1ccc(Cl)c2nonc12)N1CCc2ccccc2C1 +CCC(=O)Oc1ccc(C(=O)NC2CCCC2)cc1 +O=C(Cn1c(CCO)nc2ccccc21)N1CCCc2ccccc21 +COCCSc1nncn1C(C)c1ccccc1 +COc1cc(CNC(=O)NC(C)c2cc(C)sc2C)ccc1O +CCN(CC)S(=O)(=O)NCc1ccn(-c2ccccc2)n1 +COc1cccc(OC)c1C(=O)OCC(=O)NC1CCCC(C)C1C +COC(=O)c1ccc2c(=O)[nH]c(Cc3ccc(OC)c(F)c3)nc2c1 +CC(C)Nc1cccc(CNC(=O)c2scnc2C2CC2)c1 +O=C(CCOc1ccccc1F)NCc1ccc2c(c1)OCO2 +CC(Oc1ccc(C#N)cc1)C(=O)NCc1ccco1 +COc1ccc(C)cc1NC(=O)C1Cc2ccccc2C(=O)O1 +O=C1CCN(C(=O)c2cc3ccccc3[nH]2)CCN1 +CN(CCC(F)(F)F)C(=O)Nc1ccccc1SCC(N)=O +O=C(CCn1ccccc1=O)Nc1cccc(OCC2CCCO2)c1 +O=c1[nH]n(-c2ncnc3sc4c(c23)CCC4)c(=O)c2ccccc12 +CCN(CC)C(=O)C(C)N1CCOC(c2ccc(Cl)cc2)C1 +Cc1ccc(OCC(=O)N2CCN(c3ncccc3C#N)CC2)cc1 +CCOc1ccc(C2CCCN2Cc2nc3ccccc3[nH]c2=O)cc1 +CCc1nc(C2CCCN2C(=O)c2cc(C(N)=O)cs2)no1 +CCOC(=O)c1ccc(CNC(=O)c2ccncc2Cl)o1 +CC(=O)c1c(C)[nH]c(C(=O)N(C)CC2=CCC(C3CC3C)O2)c1C +CSc1ccc(S(=O)(=O)Nc2ccccc2)cc1 +Cn1ccsc1=NC(=O)CSc1ccc(F)cc1 +Cc1nccn1-c1nc2nonc2nc1Nc1ccc(F)cc1 +COc1ccc(CN2CCOC(c3cccs3)C2)cc1 +CC(Oc1ccc(C#N)cc1)C(=O)NC(C)c1nc2ccccc2[nH]1 +CCCc1csc(NC(=O)CNC(=O)c2ccc3c(c2)CCC3)n1 +CCN(C(=O)COc1ccc(F)cc1F)C1CCCC1 +COc1ccc(CN(C)C(=O)c2cc(C)sc2C)cc1 +COC(=O)c1cc(CN(C)C(=O)Nc2cc(F)ccc2C)oc1C +Cc1ccc(C(=O)N2CCCC(c3nncn3C)C2)cc1 +CCc1cc(=O)n2c(n1)SCC2CC(=O)N1CC(C)OC(C)C1 +Cc1ccc(-c2noc(C(=O)NCc3ccco3)c2N)cc1 +COc1cccc(C(=O)NCCNC(=O)c2nc(C3CC3)no2)c1 +CN(C)C(=O)Cc1csc(-c2ccccc2N)n1 +COCc1ccccc1NC(=O)Cn1cnc2c(C)cccc2c1=O +COc1ccc(C2(Cc3sccc3C)NC(N)=NC2=O)cc1 +COc1cccc(C(=O)NCc2ccsc2)c1OC +Cc1ccc(NC(=O)CN2CCN(c3ccc(F)cc3)CC2)cc1N +COc1ccc(NC(=O)C(C)NC(=O)c2ccccc2F)cc1 +CC(O)c1cc(Br)ccc1OCCc1ccncc1 +O=c1[nH]c(N2CCN(c3ccccc3)CC2)nc2c1CCC2 +COc1ccccc1-c1ccccc1C(=O)N(C)Cc1cnn(C)c1 +COc1ccc(Cc2cnc(NC(=O)C(C)NC(C)=O)s2)cc1 +CN(CC(=O)OC(C)(C)C)C(=O)c1ccccc1Br +CCc1nsc(N2CCN(CC=Cc3ccccc3OC)CC2)n1 +CNC(=O)C1CCCCN1C(=O)c1scnc1C1CC1 +CCn1cc(Cl)c(C(=O)Nc2ccsc2C(=O)OC)n1 +O=c1n(Cc2nc(Cc3ccccc3Cl)no2)nc2ccccn12 +CCc1cccc(C)c1NC(=O)c1cn2ccccc2n1 +Cc1cc(S(N)(=O)=O)sc1C(=O)NC1CCCCC1C +COc1ccncc1NC(=O)Cc1cccc(OCC#N)c1 +Nc1oc2ccc(O)cc2c1-c1nc2c(s1)CCCC2 +CCC(C(=O)Nc1ccc(F)cc1)n1c(=O)[nH]c2ccccc2c1=O +COC1CCCC(OC(=O)CCC(=O)c2cccs2)C1 +CN(CC(=O)Nc1ccc(OC(F)(F)F)cc1)C(=O)C1CCCO1 +CN(C)C(=O)C(OC(=O)c1cc2c(s1)CCC2)c1ccccc1 +CCCn1cc(N)cc1C(=O)N(C)Cc1cscn1 +Cc1occc1C(=O)N1CCC(OCc2ccc(F)cc2)CC1 +CC(C)c1ccc(C2CC2C(=O)NCC(O)C2CCOCC2)cc1 +Cc1noc(C2CCCN(C(=O)c3cc(Cl)c[nH]3)C2)n1 +COCc1ccc(C(=O)NCc2cccnc2OC2CCCC2)o1 +COc1cc(C(=O)NCCOc2ccccc2)on1 +O=C(Nc1ccccc1C(=O)N1CCOCC1)C1CC2CCC1O2 +CCN(CCO)C(=O)CC(c1ccccc1)c1ccccc1 +Cc1cc(C(=O)NCC(=O)NCc2ccncc2)n(C)n1 +O=C(C1CCCC1)N(Cc1ccccc1F)C1CC1 +CCCNC(=O)CCNC(=O)Nc1cccc2ccccc12 +O=C(Nc1cccc(Cl)c1)N1CCN(Cc2cccc(O)c2)CC1 +Cc1noc(C(C)NC(=O)c2cc3ccccc3cc2O)n1 +COc1nn(C)cc1C(=O)Nc1ccc(-n2ccnc2C)nc1 +O=C(Cc1cccc(F)c1)OCCCc1ccncc1 +O=C1CCC(=O)C(c2ccc(Br)cc2)N1 +Cc1noc(C)c1CN1CCOC2CCC1C2OCC1CC1 +COc1ccc(Nc2ncnc3onc(C)c23)cc1Cl +CC(C)(C)OC(=O)NCC(=O)NCc1cccc(-n2ccnc2)c1 +COc1ccc(NC(=O)N2CCN(C(=O)C3CCCO3)CC2)cc1 +COc1ccc(C(=O)NCc2ccc(C)cc2C)cc1 +CC(C)c1ccc(C(NCC(F)(F)F)C(N)=O)cc1 +CCC(Sc1cc(C#N)ccn1)C(=O)NCc1ccccc1 +Cn1c(Cc2cccs2)nnc1SCC(=O)NC(C)(C)C +O=C(Oc1ccc2c(c1)OCCO2)c1ccccc1F +CCOC(=O)c1cccc(Nc2cc(C)nc(C)n2)c1 +Cc1nc(C)c(C(=O)N2CC(C)(C)C(C)(O)C2)s1 +c1sc(C2CC2)nc1CNc1nc(C2CC2)no1 +CC(Cn1cccn1)NC(=O)NCCN1CCOCC1 +Fc1cc2ncnc(N3CCCC4CCCC43)c2cc1F +CC(NC(=O)c1ccc(Cl)cc1)C(=O)NC(C#N)c1ccsc1 +COc1ccc(OC)c(CCc2ncc(N)cn2)c1 +Oc1ccc2c3c(ccc2c1)CCNC3c1ccc[nH]1 +CCCN(CCO)C(=O)Nc1cccc(Cl)c1 +CC(C)c1noc(CCNC(=O)NCc2cccc(F)c2)n1 +Cc1cc(-n2nc(C)nc2-c2c(C)nc3ncccn23)ccn1 +Cc1cc(NC(=O)CN2CCN(C(=O)C3(O)CCCC3)CC2)no1 +COCCOCC1NCCc2cc3cc[nH]c3cc21 +CCOC(=O)C1=C(C)NC(=O)NC1c1cccs1 +Cc1nn(C)c2ncc(C(=O)OC(C(N)=O)c3ccccc3)cc12 +CC(C)CN(Cc1ccsc1)C(=O)Cn1cccnc1=O +N#Cc1ccc(N2CCN(c3cncc(C#N)n3)CC2)cc1 +Cc1cc(C(=O)Nc2ccc(-n3ccnc3)nc2)no1 +CCN(CC)C(=O)C(C)Oc1ccc(SC)cc1 +O=C(Cc1ccc(F)cc1)Nc1cccc2c1CCCN2 +O=C(Nc1nc(C2CC2)cs1)c1ccc(Oc2cccnc2)cc1 +CC(=O)c1ccc(NC(=O)NCC(C)CN2CCOCC2)cc1C +CCS(=O)(=O)NCCNC(=O)Nc1ccccc1N1CCCC1 +O=c1cc(CNCCCCCO)[nH]c2c(Cl)cccc12 +Cc1ccc(CNC(=O)C2(c3cccc(C(F)(F)F)c3)CC2)cn1 +CC1CC1C(=O)N1CCN(C(C#N)c2ccc(F)cc2)CC1 +CCNC(=O)CNC(=O)c1nn(C)c2ccc(Cl)cc2c1=O +O=C(Cc1c[nH]c2ncccc12)NCc1ccc(Cl)cc1 +CCOCCOCC(=O)N(C)c1cccc(C)c1C +COCc1nc(CNC(=O)Cc2csc(C)n2)no1 +COc1ccc(Nc2nc(C)cc(C)c2C(N)=O)c(OC)c1 +Cc1cccc(N(C)C(=O)c2ncn(-c3ccccc3)n2)c1 +CCn1c(SCc2cccc(F)c2)nnc1-c1ccncc1 +CCOc1ccccc1NC(=O)CSc1nc2cccnc2n1C +O=c1c2[nH]c3ccc(F)cc3c2nc2n1CCCS2 +CC(C)C(C(=O)Nc1nccs1)n1nnc2ccccc2c1=O +Cn1[nH]c(=O)c2c(C(=O)NCc3ccc(F)cc3)cc(C3CC3)nc21 +COc1cccc(NC(=O)C(C)NC(=O)c2ccco2)c1 +CC(C)(C)c1ccc(C(=O)NCC2CCCO2)cc1 +O=C(C1CC1)N1CCC(NS(=O)(=O)c2ccccc2)C1 +Cc1cc(C)n(CCCNC(=O)c2cc3sccc3n2C)n1 +CC(C)c1cc(C(=O)NCc2cncnc2N)on1 +CSc1ncccc1C(=O)NCCCc1nc2ccccc2[nH]1 +O=C(NCc1ccccc1Cl)c1ccccc1F +Cc1noc(C)c1C(=O)NC(C)c1ccc(Br)cc1 +CNC(=O)COC(=O)c1cnn(-c2ccccc2)n1 +CC(=O)NC(C)(C)c1noc(CC2OCCc3ccccc32)n1 +CC(=O)NCc1ccc(C(=O)NC(C)c2cccc(Cl)c2)cc1 +CCn1cc(NC(C)C(=O)Nc2ccc(Cl)cn2)cn1 +CCSc1sc(C(=O)c2ccccc2)c(N)c1C#N +CCOC(=O)Cc1ccccc1NC(=O)c1ccc(C)nc1 +COC(=O)c1cccc(C(=O)Nc2cccnc2-n2ccnc2C)c1 +Cc1ccc(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)nc1 +CN1CCN(S(=O)(=O)c2cccc(F)c2)Cc2cccnc21 +CCCn1c(C)nnc1SCC(=O)NC(C)(C)C +COC(=O)CCS(=O)(=O)c1ccc(F)cc1F +Cc1ccc2c(Br)ccc(OCc3nnc(C)o3)c2n1 +COCCOc1ccccc1NC(=O)CC1CCCO1 +O=C(CCn1ccc2ccccc21)NCc1ccnc(C2CC2)c1 +CN(CCOC(=O)Nc1cccc(Cl)c1)c1ccc(C#N)cn1 +O=C1CN(C(=O)CCCSc2ccccc2)c2ccccc2N1 +COc1cccc(C(=O)NCC(=O)NCC2C(=O)N=C(C)C=C2C)c1 +CC1Cc2ccccc2N1CC(=O)NC1CCCc2ccccc21 +CCC(C(=O)Nc1ncccc1Br)N1CCCC1=O +CS(=O)(=O)NCCc1ccc(C(=O)NCc2ccco2)s1 +C=C(C)COc1ccc(C(=O)NC(C)CC)cc1N +Cc1ccccc1C(C)NC(C)C(=O)Nc1ccc(C#N)cc1 +O=C1CC(c2ncccc2Br)NCCN1 +COc1cc(Cc2nc(C)c(N)c(C)n2)c(OC)cc1C +Cc1ccc(=O)n(CC(=O)Nc2c[nH]cc(Br)c2=O)n1 +CC(C)(C)c1nc(C#N)c(N2CCC(C(N)=O)CC2)o1 +Cc1nn(C(C)C(=O)NCCC(C)C)c2ccccc12 +CCn1c(=O)[nH]c2cc(C(=O)Nc3ccc[nH]c3=O)ccc2c1=O +CN(C)S(=O)(=O)NCCNc1cccc(F)c1C#N +CC1c2cccn2CCN1C(=O)C1Cc2ccccc2C(=O)O1 +Cc1ccc(C(=O)Nc2nc3c(s2)CNC3)cc1C +Cc1ccccc1CNC(=O)c1ccc(Cn2ccccc2=O)o1 +COc1ccc(C(=O)CN2CCOC(C)C2)cc1C(C)(C)C +CC(NC(=O)Cn1c(-c2ncccn2)noc1=O)c1ccccc1 +CCCC(=O)Nc1ccc(OC)c(NC(=O)c2ccc(OC)cc2)c1 +O=C(NCc1csc(C2CC2)n1)c1ccc(Cn2cccn2)cc1 +CCS(=O)(=O)NCC(C)(C)c1ccc(Cl)cc1 +Cc1ncc(CNC(=O)c2cc(Cl)ccc2-n2cnnn2)s1 +Cc1cccc(NC(=O)CN(C)Cc2nc3ccccc3s2)n1 +C#CCN1CCC(C(=O)NC(C)c2ccc(OC(F)F)cc2)CC1 +CC(=O)Nc1cc(Cl)c(Cl)cc1Br +Cc1cnc(C(=O)NC(C)c2ccc3c(c2)CC(=O)N3)cn1 +Cc1ccsc1CNS(=O)(=O)N1CCC(C)CC1 +CN1C(=O)c2ccc(Cl)cc2NC1c1c[nH]nc1C(C)(C)C +COc1ccc2cc(C(N)C(F)(F)F)ccc2c1 +COc1cc(OC)cc(-c2nc3n(n2)C(=O)CS3)c1 +O=C(Nc1ccc2oc(C3CC3)nc2c1)N1CCCC(CO)C1 +NS(=O)(=O)CCN1CCN(c2nccc(C(F)(F)F)n2)CC1 +CCCNC(=O)CN1CCSc2ccc(N)cc21 +CCOCCC(=O)Nc1cc(Cl)ccc1-n1cncn1 +COc1ccc(Cl)cc1C(=O)N1CCC(Oc2ccccn2)CC1 +CC1CC1C(=O)Nc1ccc(C#CCCO)cc1F +COCc1ncc(C(=O)NCc2ccncc2)c(N)n1 +O=C(CNC(=O)C1CCCC1)Nc1c[nH]cc(Br)c1=O +CCc1ccc(NC(=O)c2cnc3ccccn3c2=O)cc1 +CC1CCCN(C(=O)CN(C)S(=O)(=O)c2cccc(Cl)c2)C1 +CCC(NC(=O)C1CCN(C(=O)C2CC2)CC1)c1ccncc1 +Cc1ccc(S(=O)(=O)NC(=O)NS(N)(=O)=O)cc1 +Cc1noc(C2CCCN(C(=O)C3CC3c3ccccc3)C2)n1 +O=C(CSc1nnnn1-c1cccnc1)Nc1ccccc1F +CCn1cc(C(=O)Nc2nncs2)c(=O)c2ccc(Cl)c(C)c21 +O=C(OCc1nc2ccccc2c(=O)[nH]1)c1ccc(C(F)(F)F)nc1 +COc1ccc(F)cc1NC(=O)NCCc1c[nH]c2ccc(F)cc12 +O=C(CCNc1ncccn1)N1CCC(Oc2ccccc2)CC1 +CC(=O)c1ccc(OCC(=O)Nc2ccccc2F)cc1 +CCC(=O)Nc1nnc(SCC(=O)c2ccc(F)cc2)s1 +Cn1c(=O)n(CC(=O)NCc2cccnc2)c2ccccc21 +CC(C)CN1CC2(CCN(C(=O)c3ccncc3F)CC2)CC1=O +COc1c(-c2cnnc(N)n2)cc(C)cc1C(C)(C)C +O=C(COC(=O)C1CCC1)Nc1cc(C2CC2)nn1-c1ccccc1 +COc1cc(OC)c(C(=O)N(C)c2nc(C)cs2)cc1OC +Cc1cccc(C(=O)Nc2nnc(-c3cccc(N)c3)s2)c1 +Cc1csc(CNC(=O)c2cccc(F)c2)n1 +Cc1cc(NC(=O)COC(=O)c2ccccc2)n(C)n1 +CC(C)c1csc(CCNC(=O)C(C)(C)C)n1 +Cc1ccccc1C(C)CC(=O)N1CCOCC1C1CC1 +Cc1ccc(NC(=O)CSc2nc(=O)n3ccc(C)cc3n2)cc1 +Cc1nn(C(C)(C)C)cc1C(C)NC(=O)NCC(F)F +CC(=O)Oc1cccc(C(=O)NCc2ccccc2Cl)c1 +O=C(Cn1cnc(C2CCC2)cc1=O)Nc1ccc(F)cc1Cl +O=C(CC1C(=O)Nc2ccccc21)Nc1ccccc1C(F)(F)F +Cc1cn(-c2ccccc2Cl)nc1NC(=O)CCc1nc[nH]n1 +COc1cccc(C(=O)NCCNC(=O)c2cc(C(C)=O)c[nH]2)c1 +COc1cccc(NC(=O)COc2ccc(C)cn2)c1 +Cc1cc(C(=O)Nc2ccc(NC(=O)c3ccco3)cc2)no1 +CCc1cc(OCC(=O)NC2CCCCC2)nc(N2CCOCC2)n1 +Cn1cc(C(=O)NCc2ccc(C(=O)c3ccco3)s2)nn1 +COc1cc(Cl)c(C)cc1NC(=O)c1cccnc1N1CCCC1 +COCC(=O)NCc1ccc2c(c1)CCN2C(C)=O +CC(=O)c1cnc(-c2ccco2)n1Cc1ccccc1 +O=C1Nc2ccccc2SC1CC(=O)N1CCOC2CCCC21 +Cc1noc(C2CCC3(CCN(C(=O)c4ccco4)CC3)O2)n1 +COCCn1cc(NS(=O)(=O)c2ccc(C)s2)cn1 +COc1ccccc1-c1cc(C(=O)N2CCC(C)CC2)n(C)n1 +COc1cc(N)c2c(c1OC)CN(CC(F)(F)F)CC2 +Cc1ccc(-c2nc3ncccn3c2NC2CCCC2)o1 +CCc1nn(C)c(CC)c1CN1CCN(C(C)c2cccnc2)CC1 +Cc1cc(OCC(=O)N2CCC(=O)CC2)ccc1Cl +CSc1ccc(-c2nnn(CC(=O)NCc3ccccc3)n2)cc1 +O=C(Nc1ccccc1C(=O)NCC1CCCO1)c1ccccc1 +O=C(NCc1nnc2n1CCCC2)NCC1COc2ccccc2C1 +COc1ccc(C(=O)NCC2(CO)CC2)cc1OC +Cc1csc2nc(Cc3cccc(C(N)=O)c3)[nH]c(=O)c12 +O=C(NCc1ccncc1)c1cc(-c2cccc(Cl)c2)[nH]n1 +Cc1noc(C)c1CN1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +COc1ccc(Cl)cc1S(=O)(=O)N1CCN(CC(N)=O)CC1 +COc1cccc(NCc2nc(-c3ccccc3)no2)c1 +CCN(C(=O)CCc1ccc(OC)c(N)c1)C(C)(C)C +COc1ccccc1CC(=O)OCC(=O)Nc1c(C)cccc1C +CCN(CCC#N)S(=O)(=O)c1ccc(OC)c(OC)c1 +CC(NC(=O)NCC1CCCC1)C(=O)NC(C)(C)C +Cn1cc(CN2CC(F)C(OCc3nc4ccc(F)cc4[nH]3)C2)cn1 +Cc1csc(NC(=O)c2cc(-c3c(C)nn(C)c3C)n[nH]2)n1 +Cc1nc(N2CC3CC(C2)C2CCCC(=O)N2C3)c2c(C)noc2n1 +CCN1C(=O)NC(c2ccc(C)o2)C(C(=O)OC)=C1c1ccccc1 +Cc1ccc(NC(=O)COC(=O)c2ccco2)c(Br)c1 +O=C(NCC1CCCO1)NC1CCc2cc(Cl)ccc21 +CCOc1cc(Cl)c(S(=O)(=O)Nc2cccnc2)cc1Cl +Cc1nc(C(=O)NC(C)CN2CCCC2=O)cs1 +CNC(=O)NCC(=O)N1CCC(c2ccccc2OC)C1 +O=C(CSc1ncn(-c2ccccc2)n1)Nc1cccc(Cl)c1 +Cc1ccc(OCC(=O)Nc2ccc(N)nc2C)cc1 +Cc1cc(-c2nnc(NC(=O)c3ccc4c(c3)OCO4)o2)c(C)o1 +c1ccc(-c2nnc(CN3CCN(c4nccs4)CC3)o2)cc1 +CCS(=O)(=O)NCc1ccccc1C#CCCO +CCN(Cc1cccc(C)c1)C(=O)Nc1ccc(F)c(NC(C)=O)c1 +Cc1nc2ccccc2nc1COc1ccc(O)cc1 +CN(C)c1ccc(C(=O)Nc2cc3c(cc2F)NC(=O)CC3)nn1 +NC(=O)CN1CCN(Cc2nc3ccccc3[nH]2)CC1 +CC(=O)Nc1ccc(S(=O)(=O)Cc2c(F)cccc2Cl)cc1 +CC(C)CCNC(=O)C(C)S(=O)(=O)c1ccc(F)cc1 +CC(=O)c1ccc(NC(=O)N2CCC(C(=O)N(C)C)CC2)cc1C +COc1cccc2cc(C(=O)NCCc3cccs3)c(=O)oc12 +CC(C)COC(=O)CN1C(=O)C(C)Oc2ccc(N)nc21 +Cc1c(NCC(=O)NC(C)C)cccc1NC(=O)C1CC1 +NC(=O)c1ccc(N2CCCC2)c(NC(=O)CC2CC3CCC2C3)c1 +Cc1cccn2cc(CS(=O)(=O)c3ccc(Cl)cc3)nc12 +O=C(Nc1nnc(-c2cccnc2)o1)c1cccc(F)c1 +COc1ccc(Cl)cc1C(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1cccc(NC(=O)c2ccc(S(N)(=O)=O)o2)c1C +CN(CC1CCCCC1)C(=O)c1ccc2c(c1)CCN2 +CCOC(=O)C1CCN(c2cccc(OC)n2)CC1 +O=C1CCCc2c1cnc1c(C(=O)NCCCc3ccccc3)cnn21 +CC12CCC(C(=O)Nc3ccc4c(c3)OCCO4)(OC1=O)C2(C)C +COc1ccc(Cl)cc1C(c1c(O)n[nH]c1C)c1c(C)n[nH]c1O +Cc1cc(NC(=O)CN2CCCNC2=O)n(-c2ccccc2F)n1 +CNc1oc(COc2ccc(Cl)cc2)nc1C#N +O=C(C1Cc2ccccc2CN1)N1CCN(Cc2ccccc2)CC1 +O=C(Nc1ccccn1)NC1CCCN(Cc2ccccc2)C1=O +COCc1nc(-c2ccc(OC)cc2)sc1CO +CCOC(=O)C1N=C(CCc2ccccc2Cl)OC1=O +CCOC(=O)CCc1ccc(NC(=O)c2ccncc2F)cc1 +Cc1nc(CN(C(=O)Nc2c(C)noc2C)C(C)C)no1 +c1cnc(NCCNc2ncnc3sccc23)cn1 +Fc1ccc(-n2cc(CNc3nnc(CC4CC4)o3)nn2)cc1Cl +O=C(NCCO)c1cccc(Nc2ncccn2)c1 +O=C(CNC(=O)Nc1nnc(C(F)F)s1)Nc1cccc(F)c1 +CC(=O)N1CCN(CC(=O)c2ccc(F)c(F)c2)CC1 +COc1cc(OC)cc(C(=O)N(C)Cc2ccc(SC)cc2)c1 +CCC(C)n1ncc(C(=O)Nc2cnc(C3CC3)nc2)c1C1CC1 +CC(C)Cc1ncc2c(n1)CN(C(=O)CC1CCc3ccccc31)C2 +Cc1cc(C)nc(SCC(=O)OCC(=O)c2cccs2)n1 +CC(C)(C)c1nnnn1-c1ccc(Br)cc1 +COC(=O)CCCn1nc(C#N)cc1-c1cccs1 +CCOC(=O)c1c(C)nc(-c2ccccc2)nc1SCC#N +COCC(=O)Nc1ncc(Cc2ccc(F)cc2F)s1 +CN(Cc1ccccc1N1CCOCC1)C(=O)CC1CC2CCC1C2 +COc1ccnc(N2CCC(c3ccnn3CCO)CC2)n1 +O=C(Nc1ccccc1F)c1ccnc(-c2ccsc2)c1 +COC(C)C(=O)Nc1cc(C(F)(F)F)ccc1F +COC(C(=O)NC(C(C)C)C(C)C)c1ccccc1 +O=C(Nc1ccc2cc[nH]c2c1)c1noc2c1CCCCC2 +O=C(CN1CCN(c2nc3cccnc3s2)CC1)NCC1CCC1 +NC(=O)Cc1csc(NC(=O)c2cnccn2)n1 +O=C(OCc1cncs1)c1cccc(-n2cnnn2)c1 +Cc1cccc(C)c1NS(=O)(=O)c1ccc(O)cc1 +CC(C)Nc1nnc(SCC(=O)Nc2ccccc2)s1 +CCNc1ncc(Br)c2c(N)cc(F)cc12 +CCC(C(=O)Nc1c(C)cccc1C)n1c(C)cc(C)nc1=O +COc1cc(OC)cc(C(=O)NC(C(=O)N2CCCCC2)C(C)C)c1 +CCn1nc(C)cc1C(=O)Nc1ccc(C)c(Cl)c1 +CCc1nc2cc3c(cc2n1CCC#N)OCCO3 +CC(=O)Nc1ccc(C)c(NCC(=O)Nc2cc(C)cc(C)c2)c1 +O=C(Nc1c(F)cccc1F)c1nccc2ccccc12 +CCc1oc(C(=O)N(c2ncc(C(=O)OC)s2)C2CC2)cc1C +Cc1cc(C(=O)Nc2ccccc2SCC(N)=O)c(C)o1 +CC(Sc1nnc(C(F)(F)F)n1N)C(=O)NCC(F)(F)F +O=C(CNC(=O)C1CCCC1)Nc1ccc(Oc2ccncc2)cc1 +CNS(=O)(=O)c1cnc(NC(C)C)c(Cl)c1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(C#N)cc1 +O=C1CCCCN1Cc1cccc(NC(=O)N2CCC(CO)CC2)c1 +COc1cc(NC(=O)C(C)c2ccsc2)c(OC)cc1Cl +Cn1cc(C(=O)Nc2ccc(Cl)cc2)c(=O)c2cc(F)ccc21 +COc1cccc(OC)c1-c1cncc(C(=O)NCc2ccco2)c1 +COc1ccc(CN(C)C(=O)CC2CC3CCC2C3)c(OC)c1 +CCOC(=O)C1=C(CC)NC(=O)NC1c1ccccc1OC +CCCC(=O)N1CCc2[nH]nc(C(=O)NCC(C)CC)c2C1 +CC1(C)CN(C(=O)Cc2cccc(OCC#N)c2)CCO1 +CC(C)Oc1ccc(CCC(=O)N2CCOCC2)cc1N +CC(C(=O)NCc1cscn1)S(=O)(=O)c1ccc(F)cc1 +CCOc1ccc(S(=O)(=O)Cc2cc(C)no2)cc1 +CCc1onc(C)c1NC(=O)NCCc1cccc(F)c1 +COc1ccccc1NC(=O)CNc1cccc(C(=O)NC(C)C)c1 +COC(CNC(=O)Cn1cnnn1)c1cccc(Cl)c1 +N#CCCN(CCC#N)C(=O)COc1cccc(Cl)c1Cl +O=C(COCC1CCCO1)NC1(c2cccc(Cl)c2)CC1 +CCc1nc2sc(C(=O)Nc3cc(C)on3)c(N)c2cc1C +CCOc1nc2cnccc2n(CCN2CCOCC2)c1=O +N#Cc1ccccc1Cn1cc(Cl)cc(Cl)c1=O +C#CCNC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c(C)c2)cc1 +O=C(OCc1noc(-c2ccc(F)cc2)n1)c1scnc1C1CC1 +Cc1cc(=O)oc2cc(OCC(=O)Oc3ccccc3)ccc12 +COc1cccc(C(=O)NC2(c3noc(C)n3)CCC2)c1F +COc1cc(OC)cc(-c2nnc3n(C)c4ccc(N)cc4n23)c1 +Cc1ccc(CC(=O)NCCC(=O)NC2CCCC2)cn1 +O=C(NCCc1ccccn1)N1CCC(Nc2ccccc2)C1 +CN1CCOC(C(=O)Nc2cccnc2N2CCC(CO)CC2)C1 +CCOC(=O)c1c(C)c(S(=O)(=O)NC(C)(C)CC)c(C)n1C +COc1cc(CO)ccc1OC1CCCCNC1=O +CCC1CCCCC1NC(=O)NC1CCN(S(C)(=O)=O)CC1 +COc1ccc(Cl)cc1NC(=O)CNc1cccc(C#N)c1 +COc1cc(CNC(=O)c2cccc(C)n2)ccc1OC(F)F +Cc1nnc(NC(=O)NCCOc2c(C)cccc2C)s1 +Cc1cc2c(cc1F)C(CNC(=O)c1ccccc1)NCC2 +Cc1cc(C)n(C2CCCN(C(=O)COc3ccc(F)cc3F)C2)n1 +c1cnc(NCC2CCC3C2OCCN3Cc2ccc[nH]2)nc1 +CC(CCNC(=O)Cc1ccc(-n2cnnn2)cc1)c1ccccc1 +Cc1noc(C)c1CC(=O)Nc1ccc2[nH]ncc2c1 +O=C(CSc1ccccc1F)OCC(=O)N1CCCC1 +CN(C)c1ccc(NC(=O)c2cccc3cn[nH]c23)cn1 +Cn1cnc2c1c(=O)n(Cc1nc(-c3ccncc3)no1)c(=O)n2C +CC1CN(C(=O)C2CCCCN2S(C)(=O)=O)c2ccccc21 +Cc1ncc(CN(C)C(=O)NCCNC(=O)C2CC2)s1 +Cc1n[nH]c(CC2OCC3CN(c4nnc(C)s4)CCC32)n1 +O=C(NCCc1ccccn1)c1cc(-c2ccccc2)[nH]n1 +CC(C)(C)NC(=O)c1cccc(NCc2ccccc2C#N)c1 +O=C(CNC(=O)Cc1ccc(Cl)cc1)NCCN1CCOCC1 +Cc1nn2c(=O)c(CCO)c(C)[nH]c2c1-c1ccc(Cl)cc1 +CCN(C)C(=O)c1cccc(OS(=O)(=O)c2c(C)noc2C)c1 +COC(=O)NCC(=O)NCCc1nc2ccccc2[nH]1 +CCNC(=O)c1cc(Cl)ccc1NCC(=O)Nc1cc(C)on1 +CCc1cc(C(=O)Nc2cccc(OC)c2)nc2ccnn12 +CCOCCCNC(=O)C(C)N1C(=O)CCCc2ccccc21 +CN(C)S(=O)(=O)c1ccc2c(c1)oc(=O)n2Cc1cnn(C)c1 +CC(C)(C)n1c(CCO)nc2cc(C(F)(F)F)ccc21 +NC(=O)COc1ccc(NS(=O)(=O)c2cccc(F)c2)cc1 +Cc1nc2cc(NC(=O)c3cn(C)nc3C(C)(C)C)ccc2n1C +CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)CC1 +CCCCN1C(=O)CCC2CN(C(=O)Cn3ccccc3=O)CCC21 +CS(=O)(=O)c1ncc(CO)n1Cc1ccccc1 +CCCCN(C)C(=O)c1cc2sc(C)c(CN3CCOCC3)c2[nH]1 +COC(=O)C1C2CCC(C2)C1NC(=O)c1ccc[nH]1 +Cc1ccc(OCC(C)NC(=O)NCC(C)C)cc1 +Cn1c(=O)n(CC(=O)NC2CCOCC2)c2ccccc21 +CCn1nc(C)c(CCNC(=O)c2cn3cc(C)ccc3n2)c1C +COc1cc(C#N)ccc1OCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +CC(=O)c1ccc(NC(=O)C2CCCc3sccc32)cc1C +CCOc1c(Br)cc(C(=O)N(C)C)cc1OC +O=C(c1cccnc1)N1CCOC2C(OCC3CC3)CCC21 +Cc1ccc(-n2nnnc2SCC(=O)NC(C)(C)C)cc1 +CCS(=O)(=O)N1CCCc2cc(NC(C)=O)ccc21 +CCCC(C)N(C)S(=O)(=O)c1cc(Br)cnc1N +O=S(=O)(c1cn[nH]c1)N1CCCC1c1cc[nH]n1 +O=C(c1ccncc1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +COc1ccccc1OCC(=O)NCC(C)(O)C1CC1 +Cc1ccc(-n2ncc3c(=O)n(C4CCCCC4)cnc32)cc1 +COc1ccc(Cc2ncc3c(n2)CN(C(=O)C2(C#N)CC2)C3)cc1 +Cc1cc(C(=O)N(Cc2ccc(Cl)c(Cl)c2)C2CC2)no1 +CC1Cc2ccccc2N1C(=O)CSc1nc(N)cc(=O)[nH]1 +Cc1ccnc(Sc2cccc(Cl)c2C#N)n1 +CCCn1nccc1C(=O)N1CCN(S(C)(=O)=O)CC1 +CS(=O)(=O)N1CCCN(C(=O)c2cnn(-c3ccccc3)c2)CC1 +CCC(=O)N1CCCN(C(=O)Nc2c(C)cc(C)cc2C)CC1 +O=C(CC1C=CCC1)N1CCN(Cc2nnc3n2CCCCC3)CC1 +O=C(Cn1c(CO)nc2ccccc21)Nc1ccc(F)cc1 +O=C(NC1CC1c1ccccc1)c1c[nH]c(=O)c2ccccc12 +CCCN(CC(F)(F)F)C(=O)c1cccc2[nH]ncc12 +Cc1cc(=O)[nH]c(SCC(=O)N2CCc3ccccc32)n1 +Nc1ccccc1S(=O)(=O)NC1CCCCC1 +CCOC(=O)c1c[nH]c2ccc3c[nH]nc3c2c1=O +CCOc1c(Cl)cc(CNC(=O)Nc2cccnc2)cc1OC +CC(c1cc2ccccc2o1)N(C)C(=O)Cn1nnnc1C(C)(C)C +CCNC(=O)CC1Sc2ccccc2NC1=O +COc1cccc(C(=O)N(CC(C)C)CC(C)C)c1 +COc1ccc2c(cnn2CCC(=O)N(C)Cc2ccc(F)cc2)c1 +CCCNC(=O)CCc1c(C)nc2c3c(C)cc(C)nc3nn2c1C +O=C(c1cc(Br)c[nH]1)N1CCOC(c2ccccc2)C1 +CCC(C)NC(=O)N1CCN(CCc2ccccc2)CC1 +O=C(Nc1cccc(-c2nc[nH]n2)c1)C1CSc2ccccc2O1 +CN(C(=O)c1ccc(-n2ncc(C#N)c2N)cc1)c1ccccc1 +CN(CCC#N)S(=O)(=O)c1ccc2c(c1)CC(=O)N2 +Cc1ccc(C(=O)N(C)C)cc1NCc1cccc2cccnc12 +CCOc1ccccc1CNC(=O)NCc1ccc2c(c1)OCO2 +CN(CC(=O)N1CCC1)S(=O)(=O)c1ccc(C#N)cc1 +COc1cc(C#N)ccc1OCC(=O)NC(C)c1ccc(F)cc1F +CCOC(=O)c1ccc(CNC(=O)c2c(C)oc3c2CCCC3)o1 +COc1cc(F)ccc1N(C)Cc1nnc(-c2cccs2)o1 +Cc1cc(C)n2nc(NCc3ccc(Cl)cc3Cl)nc2n1 +CCCC(=O)NC1CCCN(C(=O)Nc2cc(OC)ccc2F)C1 +Cc1cccn(C(C)(C)C(=O)Nc2cccc(N)c2)c1=O +NC(=O)c1ccc(-c2nnn(CC(O)c3c(F)cccc3F)n2)cc1 +Cn1cccc1C(O)(c1ccnn1C)c1ccnn1C +Cc1cc2occ(CC(=O)Nc3c(C)nn(C)c3C)c2cc1C +OC(Cc1c[nH]c2ccccc12)=NCc1cn2ccccc2n1 +Cc1ccc(S(=O)(=O)NC2CCN(c3ccccc3)C2=O)c(C)c1 +COCc1ccc(C2NC(=O)CN2Cc2ccccc2)cc1 +COC1CCN(c2cccc(F)c2C(C)=O)CC1 +CCOC(=O)c1ccccc1NC(=O)CSc1ccccn1 +O=C(Cc1cccnc1)N1CCC(c2nc(-c3ccccc3)no2)C1 +CCC(C(N)=O)n1nnc(-c2ccc(Cl)cc2)n1 +COc1ccc(NC(=O)c2ccccc2N2CCOCC2)cn1 +CC#CCN1c2cccc3cccc(c23)S1(=O)=O +Cc1nonc1NC(=O)C1CCCN(CC(F)(F)F)C1 +CN(C)c1cccc(C(=O)N2CCOc3ccccc32)c1 +CCN(C(=O)COC)C(c1cccnc1)c1cc(C)cc(C)c1 +CCn1nc(NCc2ccc(OC)c(O)c2)cc1C +COC(=O)C1CCN(c2cc(=O)n(C3CCCCC3)c(=O)[nH]2)CC1 +CCN(CCO)C(=O)Nc1ccccc1C(=O)N1CCCCC1 +COc1cc(NC(C)(C)CC(C)(C)C)nc(C)n1 +COCCNC(=O)Cn1ncc2ccccc2c1=O +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)C1COc2ccc(F)cc2C1 +NC(=O)COC(=O)c1cc(-c2cccs2)nc2ccccc12 +CC(C)N(CCO)C(=O)Cn1ccc(C(F)(F)F)n1 +COC(C)C(=O)Nc1ccccc1-n1ncc2c(=O)[nH]cnc21 +COc1cc(C)ccc1NC(=O)CN(CCc1ccccc1)C(C)=O +Cc1nc(CNS(=O)(=O)c2cccc(C#N)c2)cs1 +Cc1cc(C)cc(OCCN(C)S(=O)(=O)N2CCCCC2)c1 +N#Cc1ccc(-c2noc(CSc3ccccc3Cl)n2)nc1 +CC(=O)Nc1ccc(NCC(=O)N2CCCCC2)c(C(F)(F)F)c1 +Nc1cc(C(=O)NCC2CCCOC2)c(Br)cc1F +Cc1cccc(C(C)C)c1NCC(=O)N(C)CC(=O)NC(C)(C)C +COC(=O)CN(C(=O)c1cccc(CN2CCCC2=O)c1)C(C)C +CC(C)Cn1ncc2cc(C(=O)NC3(C)Cc4ccccc4C3)cnc21 +CC(=O)NC(c1ccccc1OC(F)F)C(F)(F)F +Cc1nn(-c2ccccc2)nc1C(=O)OCC(=O)NCC(C)C +CCC1CCC(NS(=O)(=O)c2c(C)nn(C)c2C)CC1 +COc1ccccc1NC(=O)c1ccc(NC(=O)C2CC2)cc1 +CC(O)c1cccc(NCc2ccc(Cl)cc2)c1 +O=C(CN1CCCCCC1=O)NCCc1c[nH]c2ccccc12 +CN(C(=O)c1cnn(Cc2ccccc2Cl)c1)C1(C#N)CCC1 +COC(=O)C1CCN(c2ccc(Cl)cc2F)C1=O +COCC(C)NC(=O)Nc1ccc(C(C)N2CCOCC2)cc1 +COC(=O)C1=C(N)Oc2[nH]nc(C)c2C1c1cccs1 +O=C(Nc1cccc(Cl)c1F)c1ccc(-n2ccnn2)cc1 +Cn1cccc1C(=O)OCC(=O)Nc1ccc(F)cc1F +Cc1cnc(NC(=O)c2ccncc2Cl)c(Br)c1 +Cc1c(C(=O)N(C)C2CCCCC2)sc2nc3n(c(=O)c12)CCC3 +CCCCCNC(=O)NC1CCN(C(=O)c2ccoc2)CC1 +O=C(CCc1ccccc1Cl)N(CCO)CCO +CCC(CC)NC(=O)NCc1cn(-c2ccc(OC)cc2)nn1 +O=C(NCc1cccs1)C1CCN(C(=O)Nc2cccs2)CC1 +Cc1ccc(CNC(=O)Nc2ccc3c(c2)oc(=O)n3C)cc1 +Cc1ccc(CCC(=O)N(C)Cc2nc3ccccc3c(=O)[nH]2)c(C)c1 +CC(Cc1ccco1)NC(=O)c1ccc(C#N)cc1 +CCCNc1ncnc(Nc2ccc(C)cn2)c1N +COc1cc2c(=O)[nH]c(C3CC3)nc2cc1OC(F)F +Cc1ccc(CC(C)N(C)S(=O)(=O)c2ccc(C(N)=O)cc2)cc1 +COc1cc(C)ccc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +C=CCC(=O)N1CCCC(Cc2ccccc2F)(C(=O)OCC)C1 +CCOC(=O)c1c(C2CC2)csc1NC(=O)c1cccc(OC)c1 +CCOc1ccc(Br)cc1NCc1cc(C)on1 +CC1CN(S(=O)(=O)NCCN2CCCCCC2=O)CC(C)O1 +Cc1ccc(NS(=O)(=O)c2c(C)noc2C)cc1C(F)(F)F +Cc1ccc(CNC(=O)CN2C(=O)Cc3ccccc32)cc1 +CCn1cc(C#N)c(=O)n(CC(=O)N(C)Cc2ccc(C)cc2)c1=O +C=CCOc1ccc(CN(C)c2cncc(-n3cccn3)n2)cc1 +COC(=O)C(C)Sc1ccc2nnc(-c3ccc(F)cc3)n2n1 +CCOc1ccc(F)c(C(=O)N(C)CC(F)(F)F)c1F +COc1ccc(OC)c(NC(=O)CNc2ccccc2F)c1 +CCCCS(=O)(=O)NCC(=O)NC1CCc2[nH]ncc2C1 +CCn1c(=O)c(C(=O)NCC2CCCO2)nn(-c2ccccc2)c1=O +CC(=O)NC(C)C(=O)Nc1ccc(C)cc1OCC1CCCO1 +CC(C)C(NC(=O)c1ccc(CCC(C)(C)O)cc1)c1ncnn1C +c1cnc2c(CSc3nnnn3C3CCCC3)cccc2c1 +NC(=O)C1CCN(C(=O)c2cccc(Nc3ncccn3)c2)CC1 +Cn1c(SCC(=O)NCC2CCCCC2)nnc1-c1ccco1 +CCCC(NC(=O)c1csc(C)n1)c1ccc(F)cc1F +Cc1nc(N)c(Br)c(C)c1Br +Cc1cc(NC(=O)Cc2cccc(C(F)(F)F)c2)ccn1 +CCc1cc(C(=O)N(Cc2ccncc2)Cc2ccc(C)s2)[nH]n1 +NS(=O)(=O)c1ccc(NC(=O)CN2CCCc3ccccc32)cc1 +O=C(Nc1ccc(OC(=O)N2CCCCC2)cc1)N1CCCCC1 +COC(=O)c1ccc(NC(=O)N2CCCC(C)C2CO)cc1 +C=CCNC(=O)C1CC(=O)N(C)C1c1ccc(F)cc1 +O=C(COc1ccc2ccc(=O)oc2c1)NCc1cccnc1 +CCOc1cccc(NC(=O)N2CCOCC2C2CC2)c1 +NS(=O)(=O)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 +NC(=O)CSc1ccc2nnc(-c3ccc(F)cc3)n2n1 +C=CCNc1nc2sc3c(c2c(=O)n1CC)CCCC3 +COc1cccc(C2CC(c3ccc(C)cc3)=Nc3ncnn32)c1OC +CC1CCCN(c2nnc(SC(C)C(N)=O)n2Cc2ccco2)C1 +CC(=O)Nc1ccc(C#CCNC(=O)CC2CCCCC2)cc1 +COc1ccc(-c2nc(Cn3nc(C)c(C#N)c3N)no2)cc1 +Nc1cc(C(=O)OCC(=O)N2CCOCC2)ccc1Cl +COc1cc(OC)c(CNC(=O)Nc2cccc(C#N)c2)c(OC)c1 +O=C(NCCCOCC1CCCO1)c1ccc(F)cc1Cl +Cc1cc(C)nc(NC2=NCC(=O)N2c2ccc3c(c2)OCCO3)n1 +CCn1c(C)cc(C(=O)NC(C)c2ccncc2)c1C +CCOC(=O)c1c(NC(=O)CC#N)sc2c1CCCCC2 +COC(CNC(=O)COc1ccc(Cl)cc1)c1ccccc1 +CC(C)NC(=O)c1ccc(N)c(OCc2ccccc2F)c1 +Cc1nc2cccnc2n1-c1cccc(C(=O)NCc2cccs2)c1 +O=S(=O)(Cc1ccc(F)cc1)N1CCc2ccccc21 +CC(C)C(=O)N(Cc1ccco1)Cc1cc2ccccc2[nH]c1=O +CCCN(C(=O)c1cc(F)c(NC)c(F)c1)C(C)C +CN(CCc1ccccn1)C(=O)c1cc(Cl)ccn1 +Cc1nn(C)c(C)c1C(=O)NCc1cccc(N2CCCCC2=O)c1 +CCc1cc(C(N)=O)c(NC(=O)C2CC2c2ccccc2)s1 +COc1ccc(S(=O)(=O)NCCN2CCOCC2)cc1C +OCc1nnn(-c2cccc3ccccc23)c1-c1cccnc1 +COc1ccc(F)cc1NC(=O)NCC(C)N1CCOCC1 +CCc1c(C(=O)Nc2ccc(OC)cc2)cnn1-c1ccccc1 +COc1ccc(C(=O)NCc2ccc3c(c2)OCCO3)cc1 +CCc1ncc(C(=O)N2CCN(C(=O)N(C)C)CC2)cn1 +O=C(NCCO)Nc1nnc(-c2ccsc2)s1 +COC(=O)c1ccc(NC(=O)c2ccc(NC(=O)C3CC3)cc2)cc1 +Cc1nc2ccccc2n1CC(=O)Nc1nc2ccccc2[nH]1 +CCOc1ccc(C(=O)CCC(=O)N2CCNCC2)cc1 +Cn1ccnc1C(NC(=O)C1CCCCC1)c1ccccc1 +CC(C)Oc1cccc(-c2ccc(CO)c(=O)[nH]2)c1 +CC(C)Cn1nccc1NC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1ccc(CC(=O)NCc2ccnc(OC3CCC3)c2)cn1 +CC(C)(C)OC(=O)N1CCN(Cc2oc(CO)cc(=O)c2O)CC1 +CCN(Cc1ccoc1)C(=O)CCCc1cc(F)ccc1F +Cc1nc2ccc(NCc3cc(=O)n4cccc(C)c4n3)cc2s1 +CC(Cc1cccs1)n1c(=O)[nH]c2ccccc2c1=O +Cn1cc(C#N)c(=O)c2cc(C(F)(F)F)ccc21 +Cc1cccc(C)c1OCCC(=O)Nc1cnn(C(C)(C)C)c1 +CN(CC(=O)OCc1ccccc1F)S(=O)(=O)c1cccnc1 +Cc1nc(-c2cccc(C(=O)Nc3nccn(C)c3=O)c2)cs1 +CCOCCC(=O)Nc1ccnn1Cc1cccc(C)c1 +Cc1ccc(C)c2c(C)c(C(=O)N3CCC(CO)C(O)C3)[nH]c12 +Cc1cc(C(F)(F)F)cc(-c2cc(NCCO)nc3[nH]ccc23)n1 +Cc1cc(C)cc(NC(=O)c2ncc(-c3ccccn3)o2)c1 +CCNC(=O)c1ccc(NC(=O)c2cccc(C)n2)c(C)c1 +O=C1c2cc(F)ccc2-n2c1nc1ccccc1c2=O +Cc1ccc2cccc(Nc3ncnc(N4CCOCC4)c3N)c2n1 +O=C(c1ccccn1)N1CC2COCC2(COCc2ccccn2)C1 +CNC(=O)C1CC2CN(C(=O)c3cccs3)CC2N1C(C)=O +N#Cc1ccc(OCCCNc2cc(C(N)=O)c(F)cc2F)cc1 +CCN(CCO)C(=O)Nc1cc(C(F)(F)F)ccc1-n1cccn1 +COc1ccccc1OCCN(C)C(=O)c1cccc(C)c1O +CS(=O)(=O)c1cccc(NC(=O)c2cn[nH]n2)c1 +CCN(Cc1ccc(C#N)cc1F)C(=O)NC(C)c1cnn(C)c1C +O=C(CCc1ccccc1)OCC(=O)c1ccc2c(c1)OCCO2 +O=C(Cc1ccsc1)N1CCn2nc(-c3ccccc3)nc2C1 +Cc1cccnc1NC(=O)N1CCc2sccc2C1 +Cc1ccc(C(=O)NCc2nnc3ccc(C(F)(F)F)cn23)cn1 +CCc1nc(CNc2cccc(C(=O)Nc3ccccc3)c2C)no1 +O=C(NCCc1ccccc1Cl)C1CC(=O)N(c2ccccc2)C1 +CCNC(=O)c1cccc(NCC(=O)N2CCCc3ccccc32)c1 +CC(=O)c1csc(C(=O)Nc2cc(O)cc(F)c2)c1 +Cc1n[nH]cc1CN(Cc1cccnc1)CC1CCCO1 +CN(Cc1ccsc1)C(=O)CN(C)S(=O)(=O)c1cccnc1 +CC1Sc2ccc(-c3c[nH]c(N)c3C#N)cc2NC1=O +COc1cc(OC)cc(C2CCN(Cc3nc(C)cs3)C2)c1 +CC(=O)c1cccc(NC(=O)Cc2cccs2)c1 +Cn1cccc1C1COCCN1C(=O)CC1(O)CCCCC1 +O=C(NC1CCN(c2nc3ccccc3s2)CC1)C1COCCO1 +CC(=O)c1ccc(N2Cc3ccccc3C2=O)cc1 +Cn1nc(CNC(=O)Nc2cccs2)c2c1CCOC2 +CN1CC(=O)N2CC(NC(=O)c3ccc4c(c3)nnn4C)CC2C1=O +O=C1CCN(C(=O)c2cc3ccccc3o2)CCN1CC1CC1 +CC(C)Oc1ncc(C(=O)N(CC(N)=O)C2CCCC2)cc1Cl +Cn1ccc(NC(=O)CCCSc2ccc(Cl)cc2)n1 +Cc1cc(C)cc(OCCNC(=O)C2CCCN2C(=O)C2CC2)c1 +Nc1csc2nc(-c3ccccc3Br)nn12 +CCCC(C)NS(=O)(=O)c1cc(F)ccc1OC +COc1cc(Br)c(OC)c(C(=O)NC2CC2)c1 +CC1CCC(O)(Cn2cnc3c(nnn3-c3ccccc3)c2=O)CC1 +CCc1ccc(OCC(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1 +Cn1c(C2CC2)nc2c1CCN(CC(=O)Nc1nncs1)C2 +Cc1c(C(C)NC(=O)c2nccnc2C(N)=O)oc2ccc(F)cc12 +COc1ccc(NC(=O)N2CCCC2C2CCCC2)cc1NC(C)=O +Cc1ccc(C)c(S(=O)(=O)N(C)C(C#N)c2ccccc2)c1 +CC(=O)Nc1cccc(NC(=O)CSc2ccc(C)cn2)c1 +COc1ccc(C(C)=O)c(OCC(=O)N2CCc3ccccc32)c1 +CC(C)(C)NC(=O)C1CCN(c2ccccc2-n2cccc2)C1=O +COc1ccccc1CN(C(=O)Cc1c(F)cccc1F)C1CC1 +CN1CC2CCC(CC1=O)N2C(=O)c1cc2ccccc2[nH]c1=O +O=C(NC1CCCCC1)C1CCCN1C(=O)Nc1ccccc1 +Cc1cnc(C(=O)OC(C)C(=O)C23CC4CC(CC(C4)C2)C3)cn1 +CCOc1ccc(OCC)c(NCc2noc(C)n2)c1 +COCC(=O)NC(C)c1cc(OC)ccc1OC +Cc1ccc(N2CC(C(=O)NCCCn3cncn3)CC2=O)c(F)c1 +Cc1ccc(CNc2ccccc2-n2ccnc2)o1 +Cc1cccc(CNC(=O)Nc2ccnn2Cc2ccccn2)n1 +NC(=O)C1CCN(C(=O)Cc2ccc(Cl)c(Cl)c2)CC1 +O=C(CCN1C(=O)COc2ccccc21)N1CCC2(CC1)OCCO2 +COCc1ccccc1NC(=O)c1cccc(-c2ccoc2)c1 +C(=CSc1nnc(-c2ccncc2)o1)Cc1ccccc1 +Cc1ccc(C#N)cc1S(=O)(=O)NCC(C)(C)c1ccncc1 +CN(C)C(=O)c1ccccc1NC(=O)Cc1ccc(F)c(F)c1 +Cc1ccccc1-c1noc(-c2nnn(-c3ccccc3)c2N)n1 +Cn1cnc(CNS(=O)(=O)c2cc(F)ccc2F)n1 +CN(CCOc1ccccc1)C(=O)Cc1c[nH]c2ccccc12 +Cc1c(C(=O)OC(C)c2ccccc2)cnn1-c1ccncc1 +CN1C(=O)Cc2cc(NC(=O)NCCCc3ccccc3)ccc21 +Cc1cc(C)c(NC(=O)Cc2nonc2N)c(C)c1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(NC(C)=O)c(OC)c1 +Cc1c(CNC(=O)Nc2ccsc2)cnn1C +O=C(C1CCCO1)N(Cc1ccco1)c1ccc(F)cc1F +CCOC(=O)CNS(=O)(=O)c1c(C)c(C)cc(C)c1C +O=c1c(Br)cncn1Cc1nccn1CC(F)(F)F +COc1ccc2cc(S(=O)(=O)NC(C)C)ccc2c1 +COc1ccc(OC)c(CNS(=O)(=O)Cc2ccccc2F)c1 +N#CC(c1ccccc1)N1CCN(C(=O)c2cc(F)cc(F)c2)CC1 +CCCC(C)NC(=O)NCCc1ccc(S(N)(=O)=O)s1 +COc1cc(C(C)NC(=O)N2CCCC(O)C2)ccc1OC(C)C +O=C(CS(=O)(=O)c1ccc(F)cc1)Nc1ccc(F)cc1Cl +Cc1cc(C)cc(CCNC(=O)Cn2nc(C)c3ccccc3c2=O)c1 +C=CCNS(=O)(=O)c1ccc2c(c1)CC(C)N2 +CC1CCN(c2nnc(C(=O)Nc3cccnc3)c3ccccc23)CC1 +COC(=O)CCCN(C)C(=O)c1cnc2c(cnn2C(C)C)c1 +O=C(c1ccc2[nH]ccc2c1)N1CCCC(CN2CCOCC2)C1 +OCc1cnn2cccc(CN3CCc4ccccc4C3)c12 +CS(=O)(=O)NCc1cccc(NC(=O)C2CCCC2)c1 +O=C(OCC(=O)N1CCOCC1)c1ccc(-c2ccccc2)cc1 +CC(=O)NC(C)C(=O)Nc1ccc(OC2CCCC2)cc1 +O=C(c1ccc2cccc(F)c2n1)N1CCC2(CCO2)CC1 +O=C(Cc1cccnc1)Nc1cc(F)ccc1Br +Cc1ccc(CC(C)NC(=O)c2cccs2)s1 +CCNS(=O)(=O)c1cc(C(=O)NC(C)C)ccc1OC +Nc1nc2cc(F)c(F)cc2n1CC(=O)N1CCOCC1 +Cc1cc(C)c(C(=O)NC(C)Cn2cncn2)c(C)c1 +CCN(CC)S(=O)(=O)CC(=O)Nc1cccc(Cl)c1 +CCN(CCc1ccccc1)C(=O)NCc1ccnn1C +O=C(NCCNC(=O)c1ccc2cc[nH]c2n1)c1ccsc1 +CC(C)CCNC(=O)COc1ccc2c(c1)OCO2 +Cc1cc(CN(C)C(=O)NC(C)Cc2ccc(O)cc2)no1 +C=CCOc1ccc(C(=O)Nc2ccccc2C(N)=O)cc1 +CC(C)n1cc(C(=O)N2CCCC(c3cc4ncccc4[nH]3)C2)cn1 +O=C(NCc1nc(-c2ccccc2)no1)C1(c2ccc(F)cc2)CC1 +O=C(CCc1nc(-c2ccsc2)no1)NCC1CCCO1 +O=C(c1ccc(=O)[nH]c1)N1CCC(CCc2ccccc2)CC1 +CCOC(=O)c1ccc(-c2nc(-c3cccnc3)no2)cc1 +COc1ccc(OCCSc2nnc(C)n2N)cc1 +Cn1c(C(=O)NC2CCCCC2)nnc1-c1cccs1 +Cc1cc(CN(C)C(=O)c2ccc(-n3cncn3)cc2)no1 +CC(=O)Nc1cc(-c2nc(-c3ccc(C#N)cn3)no2)ccc1F +COC(=O)CCn1cc(C)c(=O)c2cc(C)cc(C)c21 +CN(CC(=O)Nc1cccc(F)c1F)c1ccccc1 +CCOC1CC(N(C)C(=O)CCc2ccncc2)C1(C)C +O=C(c1cccc2cccnc12)N(CCO)C1CC1 +COC(=O)NCC(=O)N1CCCc2cc(F)ccc21 +CCNC(=O)C1(C)Sc2ccccc2N(CC)C1=O +O=C(NCc1ccoc1)C1(c2ccc(Br)cc2)CC1 +CC(Oc1ccccc1N)C(=O)N1CCOCC1 +CC(=O)N1CCC(C(=O)Nc2nc(C(C)C)cs2)C1 +COc1ccccc1CCNC(=O)C1CC(C)OC(C)C1 +CCCNC(=O)COC(=O)c1cccc(NC(C)=O)c1 +C#Cc1cccc(NC(=O)C2Cc3ccccc3C(=O)O2)c1 +COc1ccc(C(NC(=O)C(C)C)c2nccn2C)cc1OC +COc1ccc(OC)c(C2CCCN2CCCN2CCOCC2)c1 +CN(Cc1ccccc1)C(=O)c1ccc(-c2n[nH]c3ncccc23)[nH]1 +O=C(NCc1ccc(O)c(F)c1)NCC1CN2CCCCC2CO1 +Cc1ccc(CNC(=O)CCN2CCOC2=O)cc1 +O=C(NCCOc1ccc2c(c1)CCC2)NCc1ccccn1 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)N1CCOCC1 +CN(Cc1cnn(-c2ccc(F)cc2)c1)c1nc(-c2ccccc2)no1 +CCCSc1cccc2nc(C(=O)OC)[nH]c12 +CN(C)c1cc(-c2cccc(-c3ccn(CC4CCCO4)n3)c2)ncn1 +Cc1nc(C)c(C(=O)NCCCCN2CC(C)OC(C)C2)o1 +O=C(CN1CCN(C(=O)CO)CC1)NC1CCCC1 +CC(=O)N(C)CC(=O)Nc1c(C(C)C)cccc1C(C)C +CC(Nc1ccc(CC(=O)N(C)C)cc1)c1ccc(C#N)cc1 +Nc1ccccc1SCC(=O)Nc1ccccc1Br +CC(C)(C)C(=O)N1CCN(c2nc3ccccc3o2)CC1 +O=C(NCCc1nnc2n1CCCC2)c1cncc(F)c1 +Cc1cnc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)cn1 +COc1ccc(-c2cnn3c(=O)c(C)c(C)[nH]c23)cc1 +CN(C(=O)c1cc(Br)cn1C)c1ccc(Cl)cn1 +Cc1ccc(CNC(=O)N2CCN(c3nccs3)CC2)s1 +COC(=O)CC1CCN(C(=O)C2(n3cnnn3)CCCCC2)CC1 +Cc1noc(C)c1CCC(=O)Nc1cccn(C)c1=O +CN(C(=O)c1cc(N2CCCC2=O)ccc1Cl)c1ccccn1 +Cc1nnsc1C(=O)NCC#CCOc1ccccc1F +O=C(Nc1cccc(-n2cnnn2)c1)c1cc(Cl)c[nH]1 +COc1cc(NCc2sc(C)nc2C)ccc1NC(C)=O +Cc1[nH]ncc1CCCNC(=O)N(C)CC1COc2ccccc2O1 +c1csc(CN2CC3OCCN(CC4CCCO4)C3C2)n1 +O=C(c1cccc(Cn2cccn2)c1)N1CCc2ccccc2C1 +CC(CC(=O)Nc1nccn(C)c1=O)c1ccc(F)cc1 +Cc1cccc(OCCCSc2nnc(C3CC3)n2C)c1 +Cc1nc(SCC(=O)Nc2ccccc2)c(C#N)c(C)c1C +COCC(C)NC(=O)NCC1(c2ccc(Cl)cc2)CC1 +Cc1noc(C)c1C(=O)Nc1ccc(N(C)C)cn1 +CN(C)c1cccc(C(=O)N(CC(F)(F)F)C2CCOCC2)c1 +O=C(c1ccc2c(c1)OCO2)N1CC2CC(c3nccs3)OC2C1 +Cc1noc(CN2CCOC(c3ccc(F)cc3)C2)n1 +O=C(NCc1cscn1)Nc1cccc(F)c1 +CCNC(=O)c1cc(S(=O)(=O)N2CCN(C)CC2)ccc1C +CCc1cc(NC2CCCCNC2=O)n2nc(C)c(C)c2n1 +CC(C)Cn1c(=O)oc(=O)c2cccc(Cl)c21 +Cc1nn2ccccc2c1C(=O)NCCc1ccccn1 +Cc1ccc(=O)n(C(C)C(=O)Nc2cccc(F)c2)n1 +Nc1c(Cl)ccc2c(C(=O)Nc3ccccc3F)nccc12 +CN(C)C(=O)c1ccc(C(=O)Nc2ccn(C)n2)cc1 +CCOc1ccc(NC(=O)c2ccc(C)nc2N)cc1 +COc1ccc(NC(=O)Cn2nc(C(C)(C)C)ccc2=O)cc1Cl +Cc1cc(N)nc(COc2cccc3c2CCCC3)n1 +CCCC1=C(C(=O)OC)C(c2ccc(C(=O)OC)cc2)NC(=O)N1 +Cc1ccc(Cl)c(NC(=O)COC(=O)C2CCCO2)c1Cl +CC(C)c1ccccc1OCC(O)Cn1c(CO)nc2ccccc21 +CC(C(=O)Nc1nccs1)N1CCOC(Cn2cncn2)C1 +C#CCN1CCC(C(=O)Nc2cc3c(cc2C(C)=O)OCO3)CC1 +Cc1cc(NC(=O)NCCC2=CCCCC2)ccc1-n1cnnn1 +CC(Oc1ccc(Cl)cc1)C(=O)Nc1cccc(C(C)O)c1 +COc1cccc(COC(=O)C2CC(=O)N(C(C)C)C2)c1 +COc1c(OC(F)F)ccc2c1C(CC#N)NCC2 +O=c1c2c3c(sc2nc2n1CCS2)CCCC3 +CCN(C)C(=O)c1cccc(C(=O)OCc2ccoc2C)c1 +CC1Oc2ccccc2OC1C(=O)Nc1ccncc1 +O=C(Cc1c(F)cccc1Cl)NCc1ccc2c(c1)OCCO2 +Cc1cc(F)ccc1NC(=O)N1CCC(OCc2ccccc2)CC1 +CC(NC(=O)CCC1CCCCC1)c1ccc(S(C)(=O)=O)cc1 +O=C(CCc1ccco1)Nc1cccc(C(F)(F)F)c1 +COCCN1CC(C(=O)Nc2cnn(C)c2)CC1=O +CC(C)c1nc(C2COCCN2S(=O)(=O)c2ccccc2)no1 +CC(=O)Nc1ccccc1CN1CCN(c2ncccc2F)CC1 +COc1ccc2nc(N3CCCC3)c(CC#N)cc2c1 +N#CCC=C1OC(=O)c2cccc(Br)c21 +Cc1cnccc1CN(C)c1cc(C(C)C)nc2ccnn12 +COc1c(Cl)cc(C(=O)Nc2cc(C)nn2C)cc1Cl +Cc1cccnc1NC(=O)CCc1nnc(-c2ccc(Cl)cc2)o1 +Cc1n[nH]c(Nc2ccc(Cl)c(Cl)c2)nc1=O +COc1ccc(S(=O)(=O)Nc2ccc(C)cc2)cc1OC +CCC1CN(C)c2ccccc2CN1S(=O)(=O)c1cnn(CC)c1 +CN(C)c1ccc(C(=O)Nc2ccc3c(c2)OCC(=O)N3)cn1 +C=CCNC(=O)NCC(O)c1ccc(C(F)(F)F)cc1 +CCNC(=O)CN(c1cccc(C)c1C)S(C)(=O)=O +CC(C)C(=O)N1CCCC(c2nnc(-c3ccccc3F)s2)C1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)Nc1nccs1 +CCNS(=O)(=O)c1ccc2c(c1)N(C(=O)C1COCCO1)CC2 +O=C(CC(c1cccs1)n1cccc1)NCc1ccc(F)cc1 +Cn1ccc(NCc2ccc(Br)cc2)n1 +Cc1cc(C(=O)N2CCCN(C(=O)c3ccoc3)CC2)c(F)cc1F +Cn1ccsc1=NC(=O)c1ccc(NC(=O)NC2CC2)cc1 +COCCCN(C)c1c(C#N)c(=O)n(C)c(=O)n1C +O=C(c1ncc(F)cc1F)N1CCCC(OCc2cccnc2)C1 +CC1CCCC(NC(=O)c2ccc(NC(=O)C3CC3)cc2)C1 +Cc1occc1C(=O)Nc1cccc(N2CCCC2=O)c1 +O=C(Nc1cccc(Oc2cnccn2)c1)c1ccncc1F +Cc1ccc2nc(NC(=O)c3ccc(N(C)C)nc3)sc2c1 +CC(C)CNC(=O)COc1cccc(Cl)c1Cl +CC(=O)N1CCN(CCNC(=O)Cc2c(C)noc2C)CC1 +O=C(NC1CCN(c2ccccc2)CC1)c1ccc(=O)[nH]c1 +N#Cc1ccccc1Oc1ccc(NC(=O)CCCn2cncn2)cc1 +O=C(NCCC(=O)N1CCN(c2ncccn2)CC1)c1ccccc1 +COc1ccnc(NC(=O)c2cccc(OC(F)(F)F)c2)c1 +COCCNC(=O)Cc1ccc(NC(=O)C2CCC2)cc1 +N#Cc1ccccc1CNc1cc(F)c(F)c(F)c1 +COc1ccc2cc(C(=O)Nc3ccc(C)cc3)c(=O)oc2c1 +CCc1nc2cc(OC(F)F)c(OC)cc2c(=O)[nH]1 +O=C(NCC(O)c1ccoc1)Nc1ccc(C(F)(F)F)cc1 +O=C(NCCN1CCOCC1)N1CCCC1C1CCCCC1 +N#Cc1ccsc1NC(=O)CN1C(=O)c2ccccc2S1(=O)=O +CCOc1ccc(S(=O)(=O)N(C)Cc2ccc(OC)cc2)cc1 +CN(C)C(=O)CCNC(=O)Cn1c(=O)[nH]c2ccccc2c1=O +O=C(OCC(=O)N1CCOCC1)c1cc(=O)[nH]c(=O)[nH]1 +Fc1cccc(N2CCCC3(C2)CN(c2cnccn2)CCO3)c1 +Cc1cc(C)n2nc(C(=O)NCc3ccc(F)cc3)nc2n1 +Cc1nc(CCNC(=O)c2ccc(Oc3ccccc3)nc2)cs1 +Cn1cc(S(=O)(=O)N2CCOc3ccccc32)c(=O)n(C)c1=O +O=C(NCc1ncc[nH]1)Nc1cc2c(cc1Cl)OCCO2 +COc1cccc(OC)c1C(=O)NCC(C)(C)c1ccncc1 +CCC1C(=O)Nc2c(F)cc(C(O)c3ccc(F)cc3)cc21 +COc1ccc(-n2nc(CC#N)cc2C)cc1Cl +Cc1nc(C)c(C(=O)NCCc2nc(-c3ccccc3)c(C)s2)o1 +N#CCCN1C(=O)C2(CCCCC2)Nc2ccccc21 +COc1ccc(C(=O)N2CCCCC2)nc1-c1ccc(F)cc1 +COC(=O)c1ccoc1COC(=O)c1cc(Cl)c(N)cc1OC +CC(C)CCOc1ccc(S(=O)(=O)N2CCOCC2C)cc1 +Cc1cccc2nc(CNc3ccc(Br)cc3)cn12 +CC(=O)NC1CCCN(CC(=O)NCc2ccccc2F)C1 +CC(C)Cc1n[nH]c(NC(=O)Cc2c[nH]c3ccccc23)n1 +Cc1nn(C)c(C)c1CCN(C)S(=O)(=O)c1cccs1 +CC(C)CC(C)N(C)C(=O)c1cccc(NS(C)(=O)=O)c1 +Cc1ccc(C)c(OCCc2nc(C)c(CCO)c(=O)[nH]2)c1 +CN(CC(O)C1CC1)C(=O)C1CCCN1C(=O)Cc1cccs1 +Cn1c(C(=O)NCCCOCC(F)(F)F)c(Cl)c2ccccc21 +O=C(Nc1ccccc1Cl)C1CCCN(c2ncccn2)C1 +CC(C)Oc1ccccc1CNCCc1nnc2ccccn12 +Cc1ccc(NC(=O)NCCn2cccc2)cc1OC1CCOC1 +N#Cc1cnc(-c2c[nH]c3ccccc23)cc1Cl +CC1CCN(S(=O)(=O)N2CCN(c3cnccn3)CC2)CC1 +COCc1ccc(C(=O)NC(C)c2cccc(S(N)(=O)=O)c2)cc1 +COc1cccc2c(C)c(C(=O)N3CCCC(C(N)=O)C3)oc12 +O=C(Nc1cccc(N2CCNC2=O)c1)Nc1ccc(F)c(Cl)c1 +COc1cccc(COCC(=O)N(C)CC(N)=O)c1 +O=C1NCCN1CCNc1cccc(C(F)(F)F)c1 +CCC(NS(=O)(=O)c1ccc(N)cc1C)C(C)C +C=CCN(C)S(=O)(=O)c1ccc(NC(=O)c2ccc(C)nc2)cc1 +CCCn1c(SCC(=O)NC2CC2)n[nH]c1=O +COc1ccc(NC(=O)c2ccc(NC(=O)C(C)C)cc2)c(OC)c1 +O=C(CCSc1ccc(F)cc1)Nc1ccc2c(c1)OCCCO2 +CN(C(=O)c1ccc(Cl)cc1)C(C#N)c1ccncc1 +CCCn1nc(C(=O)Nc2ccncc2)c2ccccc2c1=O +CC1Sc2ccc(C(=O)NC3CCCCC3)cc2NC1=O +NC(=O)c1oc2ccccc2c1NC(=O)CCc1cc(Cl)cs1 +CCc1nc(CCNC(=O)NC2CCOC(C3CC3)C2)sc1C +O=S(=O)(C1CCCCC1)N(Cc1ccsc1)Cc1ccco1 +COc1ccccc1C(C)N(C)C(=O)c1cc(-c2ccco2)on1 +CCNC(=O)CN1CCN(C(=O)c2cn3cccnc3n2)CC1 +COc1ccc2nnc(CCC(=O)Nc3nnc(C(C)C)s3)n2n1 +CC1=NN(c2cc(C)nc(-c3ccccc3O)n2)C(=O)C1 +Cc1cccc(NC(=O)NCCc2cc(=O)[nH]cn2)c1 +Cn1ccc(NC(=O)Cc2ccc(Cl)c(Cl)c2)n1 +CC1CC(C)CN(C(=O)Cn2nnnc2C(C)(C)C)C1 +Cc1ccc(-c2noc(CCn3nc(C)c(C)c3C)n2)nn1 +O=C(NC1(C(=O)NC2CC2)CCCCC1)c1ccc2sncc2c1 +O=C(Nc1ccc2[nH]ccc2c1)C1(n2cnnn2)CCCCC1 +Cn1cc(NC(=O)c2cn(C)c(=O)c3ccccc23)cn1 +Cc1ccnc(NC(=O)C2CSc3ncc(C)c(=O)n3C2)n1 +CCN1C(=O)NC(c2ccccc2C(=O)OC)C(C(=O)OC)=C1C +Nc1nc(SCC(=O)N2CCCC2c2cccs2)n[nH]1 +N#CCn1nncc1-c1cccc(Br)c1 +Cc1c(-c2nn3c(CC(C)C)nnc3s2)cnn1-c1ccccc1 +CC(C)NC(=O)CSc1ncnc2c1cnn2-c1ccccc1 +CC(=O)N1CCC(C(=O)Nc2cnc(-c3ccccc3)nc2)CC1 +CNS(=O)(=O)Cc1ccc(CNc2ncnc3[nH]cnc23)cc1 +CCC(C)NC(=O)C1CCCN1C(=O)c1cc(Cl)ccc1Cl +Cc1ccc(C(=O)NC2CCSc3c(F)cccc32)s1 +Cc1nccn1-c1ccc(NC(=O)c2cccc(OC(C)C)n2)cn1 +COC(=O)C1CCN(C(=O)c2ccc3ccccc3c2)CC1 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccc(F)c(F)c1 +CC(C)(C)OC(=O)NCCC(=O)NCC#Cc1ccccc1 +CCOCc1cccc(NC(=O)NC2CCCn3nc(CC)nc32)c1 +Cc1cnc(C(=O)Nc2cc(C)nn2-c2ccccc2F)cn1 +CCS(=O)(=O)N1CC(OCc2ccc(OC)c(F)c2)C1 +Cc1noc(C)c1C(=O)N1CCN(Cc2ccncc2)CC1 +CCC(C)NC(=O)c1ccc(S(=O)(=O)NC)o1 +CN(Cc1ccc(F)cc1)C(=O)CCc1nc2ccccc2[nH]1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)NCCSc1ccccc1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc(Cl)cc2)CC1 +O=C1Cc2cccc(C(=O)NCc3ccccc3Cl)c2N1 +CCCN(CCO)C(=O)NC(C)C(=O)N1CCCCC1 +CNC(=O)CCCC(=O)c1ccc(OC)c(F)c1 +CC(=O)N(Cc1cc2cc(C)cc(C)c2[nH]c1=O)CC1CCCO1 +CCOCCCNC(=O)c1nc2cccnc2n(CC)c1=O +CNC(=O)c1cc(S(=O)(=O)N2CCC(C)CC2)cs1 +CC(C)Cc1nnc(NC(=O)NCc2ccncc2)s1 +O=C(C1CC1(Cl)Cl)N1CCC(C(O)c2ccccc2)CC1 +CC(C)N(C(=O)CCNS(=O)(=O)c1ccccc1)C1CCC1 +COCc1cc2n[nH]c(=O)n2c(-c2ccc(F)cc2)n1 +CN(C(=O)CNC(=O)Cc1ccccc1)C1CCCCC1 +O=C(CC1C(=O)CCc2ccccc21)c1ccccc1 +CCN(CC(C)C)C(=O)c1[nH]nc(C2CC2)c1Br +COc1cccc(NC(=O)CS(=O)(=O)c2cc(C)ccc2C)c1 +O=C(Cc1noc(Cc2ccc(F)c(F)c2)n1)NC1CCCCC1 +COc1ccc(C(=O)c2cc(C)ccc2OC)cc1OC +Cc1noc(C)c1CN(C)C(=O)CCCc1ccc(Cl)cc1 +CC(=O)c1cc2ncc(C(=O)N3CCc4ccccc4C3)cc2[nH]1 +CC(C)c1ccsc1C(=O)OCCNc1cccnn1 +CC1CCCC(CNc2cnn(CC(F)(F)F)c2)C1 +COc1ccc2c(c1)C(O)C(N1CCC(=O)CC1)CO2 +O=C(NCCNc1ncccn1)NCC1(c2ccccc2)CC1 +Cn1c(CO)nnc1SCCC(=O)NCc1ccc(F)cc1 +Cc1ccc(CN(C)C(=O)C2CC(=O)N(CCc3ccccc3)C2)o1 +COc1ccc(C(=O)NCCN2CCN(C(=O)C3CCC3)CC2)cc1 +COc1ncnc2c1CCN(C(=O)c1ccccc1C(F)(F)F)C2 +COc1ccc(Cl)cc1C(=O)N1CCN(c2ccc(C)nn2)CC1 +Cc1ccc(C(C)NC(=O)C2CC(=O)N(C(C)C)C2)s1 +COc1ccc(F)cc1NC(=O)CNC(=O)OCc1ccccc1 +O=C(NC(c1ccccc1)c1ccccc1)c1ccc(=O)[nH]c1 +CCc1nc2cc(OC)c(OC)cc2n1Cc1ccccc1C#N +Cc1ccc(-n2ccnc2)c(C(=O)Nc2ccc3oc(C)nc3c2)c1 +CN(CCN1CCCC1=O)C(=O)Nc1ccc(C#N)cc1 +CCc1nc(NC(=O)c2cc(C)n(-c3nccs3)c2C)sc1C +CN1C(=O)CCC(C(=O)NCc2ccco2)C1c1ccccc1 +Cc1ccccc1CC(C)NC(=O)Cn1cccn1 +Cc1c(C(=O)N2CCCC(n3cccn3)C2)cnn1-c1ccccc1 +CC1COCCN1C(=O)NCc1ccnc(OCc2ccccc2)c1 +CC(C)NC(=O)CSc1ncc(-c2ccc(Cl)cc2)o1 +C=C(C)CSc1nnc(NCC2CCCO2)s1 +CCc1nn(C)c(NC(=O)NCCN2CCOCC2)c1CC +COc1ccc2[nH]c(=O)c(CN(C)C(=O)CC(C)C)cc2c1 +O=C(OCC(=O)N1CCCC1)c1cccc(OCc2cscn2)c1 +Nc1ccc(SC2CS(=O)(=O)c3ccccc32)cn1 +O=C(COCC(F)(F)F)NCC(=O)Nc1ccc(Cl)cc1 +C#CCN1CCN(C(=O)NC(C)c2ccc(-c3cncnc3)cc2)CC1 +CN(C)C(=O)c1cccc(NC(=O)CCn2ccc3ccccc32)c1 +COCCN(C(=O)c1cn2ccccc2n1)C1CC1 +Cc1ccsc1CNC(=O)CSc1ncn(-c2ccccc2)n1 +O=C(Cc1ccc[nH]1)NCc1ncc(-c2ccccc2)o1 +COC(=O)C1CCCN(c2cccc3cnccc23)C1 +COc1ccc(CNC(=O)CSc2cccc3cccnc23)cc1 +COC(=O)c1ccn(COc2cccc(C(F)(F)F)c2)n1 +CCOc1ccc(NC(=O)CN2CCCCC2=O)cc1OC +O=C(CCc1cccnc1)N1CCCC(Cc2nc3ccccc3[nH]2)C1 +CCOC(=O)C1=C(C)N=C(c2nc(N3CCOCC3)sc2C)C1C +CCOC(=O)CN(CC)C(=O)c1cc(F)cc(F)c1 +COc1ccccc1C(=O)Nc1ccc(C(=O)N(C)C)cc1 +Cc1cn(C)nc1C(=O)Nc1nc2c(C)c(C)ccc2s1 +COc1ccc(CN2CCOC3(CCC3)C2)cc1OCCCC#N +OCc1cc2c(cc1OCCn1cccn1)OCO2 +Cc1cc(CN2CCN(C(=O)NCc3csc(C)n3)CC2)on1 +O=C(NCCN1CCCCCC1=O)Nc1nccs1 +O=C(Cn1c(C2CCCCC2)nc2ccccc21)NCC1CC1 +CCn1c(CNCC(=O)NC(C)(C)C)nc2ccccc21 +CC(C)CCNC(=O)C1CC(=O)N(C2CCCCCC2)C1 +Cc1ncc(CNC(=O)CCC(=O)N2CCc3sccc3C2)s1 +Cc1ccccc1C1CN(C(=O)CC(C)c2ccncc2)C(C)CO1 +Cc1cccc(NC(=O)c2coc(NC(=O)c3ccccc3)n2)c1C +CC(NC(=O)C1CC(=O)N(c2ccc3c(c2)CCC3)C1)c1ccco1 +O=C(OC1CCCc2ccccc21)c1ncn(-c2ccccc2)n1 +Cc1cc(CN(c2cn[nH]c2)S(=O)(=O)c2cccc(C#N)c2)on1 +Cc1nn(C)c(C)c1NC(=O)Cn1c(=O)n(C(C)C)c2ncccc21 +COc1cccc(-c2nc3cc(Cl)cnc3n2CCCC#N)c1 +Cc1ncsc1C(=O)N(CC(C)C)CC(C)C +COc1ccc(CCC(=O)Nn2cnc3ccccc3c2=O)cc1F +O=C(c1cc(Cl)ccc1Cl)N1CCN(c2cnccn2)CC1 +COCCn1cnnc1SCC(=O)NC1(C#N)CCCCC1 +Cn1nnnc1NCc1cc(Br)ccc1OCC(N)=O +Cc1ccc(C(=O)Nc2n[nH]c(-c3ccccc3F)n2)s1 +CC(C)CCOCCNC(=O)c1c[nH]c2ccccc12 +CN(C)c1noc(-c2cc3c(cc2Br)NC(=O)CO3)n1 +CC(C)Oc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1 +COC(=O)c1ccc(CN(CCC#N)C(C)C)cc1 +Cc1cc(C)n(CCCNC(=O)CNC(=O)c2cc(Cl)ccn2)n1 +CCCc1nc(CNc2ccc(C(N)=O)cc2)cs1 +Clc1ccc(Cn2ncc3c(-n4cccn4)ncnc32)c(Cl)c1 +Cc1nn(C)c(-c2ccc3nc(C4CC4)[nH]c3c2)c1N +COc1nn(C)cc1C(=O)OCc1cc(-c2ccccc2F)on1 +COc1ccc(NC(=O)NC(C)c2ccc(NC(N)=O)cc2)cc1 +COCC(=O)NCc1cc(=O)oc2c(C)c(C)ccc12 +CCN(CCn1cccn1)C(=O)C1COc2c(cccc2OC)C1 +COc1ccc(Cl)cc1NCC(=O)NCC(C)N1CCOCC1 +CCN1C(=O)C(C)c2cc(C(O)c3ccccc3F)ccc21 +CNS(=O)(=O)c1cccc(C(=O)N(C)C(C)C2CC2)c1 +O=C(CC1CCCC1)N1CCN(C(=O)C2CC2)CC1 +Cc1cc(C)n(CC2CCCN2C(=O)Cc2csc(C)n2)n1 +Cc1ccc(-c2nnc(SC3CC(C)OC3=O)n2C)cc1 +COc1cccc(Nc2ncnc(Nc3cc(C)ccn3)c2N)c1 +CC1CCCCC1NC(=O)NCc1ccnc(OCC(F)(F)F)c1 +NC(=O)c1ccc(F)c(CNc2cccc3ccccc23)c1 +Cc1c(C(=O)NCCc2cccs2)cnn1-c1ccncc1 +CCCOC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 +CC(=O)N1Cc2ccccc2CC1C(=O)Nc1ccc2ccccc2n1 +CCCNC(=O)CNC(=O)c1cc(Cl)ccc1OC +Cc1nc(OCC(=O)Nc2ccc(F)cc2)c2ccccc2n1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)C(C)c1cccnc1 +CNC(=O)C(CC(C)C)NS(=O)(=O)c1cc(F)ccc1C +COC(=O)C1(N(C)C(=O)c2cc(OC)cs2)CCCCC1 +COCc1cccc(CNC(=O)c2cnc3ccc(C)cn23)c1 +CC(C)(C)NS(=O)(=O)c1cc(C(=O)NCCO)ccc1Cl +COC(=O)c1ccc(Cl)cc1S(=O)(=O)N1CCN(C)CC1 +CCOC1CC(NC(=O)Nc2cc(C)on2)C12CCC2 +c1ccc2oc(Oc3ccc(-n4ccnc4)cc3)nc2c1 +O=C(CSc1nnc(-c2cnccn2)s1)c1ccc(Cl)cc1 +FC(F)(F)c1cnc(-n2cc(Br)cn2)c(Cl)c1 +CCn1cc(Cl)c(C(=O)N2CCN(C(=O)c3ccco3)CC2)n1 +Cc1cnccc1NC(=O)N(C)Cc1cccc(N(C)C)c1 +CCc1cc(C#N)c(NC(=O)CCCc2nc(C(C)C)no2)s1 +O=C(CSc1ccc(Cl)cc1)NCCC(=O)N1CCCC1 +c1cncc(CN(Cc2ccco2)c2ccc3nccnc3n2)c1 +CC(=O)c1nc2cccc(F)c2n1Cc1cccc(C#N)c1 +COC(=O)c1cc(N)cn1CCCc1ccccc1 +C=CCN1CC2(CCC1=O)CCN(C(=O)Nc1cccc(F)c1)CC2 +CC1Oc2ccc(-c3cc(=O)[nH]c(N)n3)cc2NC1=O +CC1(C)CC2CC(C)(CN2C(=O)c2ccc3[nH]ccc3c2)C1 +O=C(c1ccncc1F)N(CCc1ccccc1)C1CCCC1 +CCOc1cc(C(=O)N2C(C)COCC2C)ccn1 +CN(C)c1ccc(C(=O)NCc2cccs2)cc1F +CC(C)CN(CC(C)C)C(=O)Nc1ccccc1S(C)(=O)=O +CC(C)c1nc(C2CCCN2Cc2nnc(C3CC3)o2)no1 +O=C(NCC(=O)N1CCCCC1)c1ccc(Cl)cc1Cl +N#CCSc1nc(C2CC2)cc(C(F)(F)F)c1C#N +COC(=O)c1ccc(C(=O)NC2CCOC2C)s1 +O=C(c1scnc1C1CC1)N1CCN(c2cccs2)CC1 +COc1ccc(NS(=O)(=O)c2cc(C)sc2C)c(OC)c1 +NC(=O)c1ccc(NC(=O)CC2=CCCCC2)cc1Cl +COCC(=O)Nc1ccc2nc(NC(=O)c3ccccc3)sc2c1 +CCCC(C)NC(=O)c1c(F)c(F)c(F)c(F)c1F +COCCC(=O)N1CCOC(Cc2cccc(C(F)(F)F)c2)C1 +CCc1cc(NCCNc2cccnc2)n2nc(C)c(C)c2n1 +Cc1cccc(NC(=O)CSc2nnc(-c3cccnc3)n2C)c1 +N#CC(Cc1ccccc1Cl)C(=O)N1CCOCC1 +Cc1nc(CC(=O)NC(C)CCc2ccccc2)cs1 +OC(COCc1ccccc1F)CN1CCN(c2ncccn2)CC1 +CNC(=O)c1cc(NC(=O)C(C)C)ccc1Cl +CCC(=O)N1CCCC(C(=O)N2CCOc3ccc(F)cc32)C1 +Cc1ccc(N2CCN(C(=O)Cc3cccc(F)c3)CC2=O)cc1 +O=C1CN(C(=O)c2cc3sc4ccccc4c3s2)CCN1 +CCc1ccc(CNC(=O)COC(=O)c2ccc3ccccc3n2)cc1 +Cc1cc(NC(=O)CN2CCN(c3cccc(Cl)c3)CC2)no1 +O=C(Nc1ccc(CN2CCCC2=O)cc1)c1cccs1 +O=C(Nc1cn[nH]c1)NC(c1ccc(Cl)cc1)C1CC1 +Cc1cc(C2CCCN2C(=O)Nc2ccccc2)on1 +Cc1cc(Br)c2occ(C#N)c(=O)c2c1 +Cc1cc(=O)n(CCNC(=O)c2c[nH]c(=O)[nH]2)cn1 +CCOc1ccc(Cn2c(=O)oc(=O)c3ccccc32)cc1OC +Cc1ccc2ncc(C(=O)N(CC(=O)N(C)C)CC(F)(F)F)n2c1 +CCCN(CCC)C(=O)Cn1c(=O)cnc2ccccc21 +COc1ccc(-c2nc(CC#N)c(C)o2)cc1OC +Cc1nc(CNC(c2ccccc2)c2cccc(F)c2)no1 +CCCc1cc(=O)n(CC(=O)NCc2ccc(Cl)cc2)cn1 +CC1CN(C)CCN1C(=O)c1cc(=O)[nH]c2ccccc12 +O=C(OCc1ccccn1)c1ccc(Cn2ccccc2=O)o1 +O=C(c1cc(-c2cccs2)on1)N1CCCCC1Cn1cccn1 +CCNc1nc(C)c(C(=O)N(C)Cc2snnc2C)s1 +CCCC(=O)N1CCCC(C(=O)Nc2ccc(Cl)c(F)c2)C1 +CC(OCc1ccccc1)C(=O)Oc1ccccc1F +CCCc1cc(C(=O)NCC2CCCN(c3ncccn3)C2)[nH]n1 +CC(C)NC(=O)N1CCC2(CC(Nc3cccc(C#N)n3)CO2)C1 +CC(=O)NCC(=O)NCC(=O)Nc1cc(CC2CCCCC2)n[nH]1 +O=C(c1cnn2c(-c3ccccc3)ccnc12)N1CCOCC1C1CC1 +Cc1ccc2c(cnn2C(=O)CCC(=O)NCc2cccc(F)c2)c1 +Cc1n[nH]c(C)c1CC(C)C(=O)NCC(O)c1ccccc1F +COC(=O)CNC(=O)c1ccc(NC(=O)c2ccc(F)cc2F)cc1 +O=C(Nc1ccnn1C1CCCCC1)c1ccc(-n2cncn2)nc1 +Cc1cc(COC(=O)c2ccc(F)cn2)nc(N2CCCCC2)n1 +COc1ccc(C)c2c1N(CCN1CCCS1(=O)=O)CCC2 +CC(C)NC(=O)CCNc1c(-c2ccc(F)cc2)nc2cnccn12 +CC(=O)N1CCC(CN(C)C(=O)Nc2cc(F)cc(Cl)c2)C1 +NC(=O)c1cc(-c2cccs2)nc2ccccc12 +Cc1nc(C)n(C2CCCN(C(=O)c3ccn(C(C)C)n3)C2)n1 +CC(C)(C)C(=O)N1CCC(NC(=O)c2cccc3[nH]ncc23)CC1 +Cc1ccc2ncn(CC(=O)NCc3cccs3)c(=O)c2c1 +Cc1occc1C(=O)NCCC(=O)N1CCCC1 +COc1ccc(C(C)(O)c2ccccc2OC)cc1 +CCC(CC)NC(=O)Nc1ccc(NC(=O)C2CCCO2)cc1 +COC1CN(C(=O)c2ccoc2)C2CCCOC12 +CCC(=O)N1CCCC(C(=O)N=c2[nH]c3ccccc3n2CC)C1 +CC(C)NC(=O)CNc1ccc(C(=O)NCc2ccco2)cc1 +CCOc1cc(F)ccc1NC(=O)c1cccs1 +O=C(NCC1CC2C=CC1C2)c1nc(-c2cccs2)no1 +CC(C)COC(C)C(=O)Nc1cnn(C(C)(C)C)c1 +CCCN(C)C(=O)C1CCCN1S(=O)(=O)c1ccc(C)s1 +C#CCCOC(=O)c1ccccc1CS(=O)(=O)c1ccccc1 +COc1ccc(OC)c(-c2csc(Cc3csc(C)n3)n2)c1 +COc1ccccc1Oc1ccc(NC(=O)N(CCO)C2CC2)cc1 +COCCNC(=O)c1nnsc1-c1ccc(Cl)cc1 +Cc1ccc(-c2nc(C)sc2CC(=O)N2CCOCC2)cc1 +Cc1oc(C(=O)NCCc2ccccn2)cc1S(N)(=O)=O +CC(C)C(C)(C#N)NC(=O)CSc1nc2ccccc2c(=O)n1C +Cc1nc(CNC(=O)N2CCN(Cc3cccnc3)CC2)cs1 +COc1ccccc1CN(C1CC1)S(=O)(=O)c1ccccc1F +CCNC(=O)c1cn2c3c(cc(Br)cc3c1=O)CC2 +CC(=O)c1cccc(NC(=O)Cc2csc(-c3ccsc3)n2)c1 +CS(=O)(=O)N1CCC(c2noc(-c3ccccc3)n2)CC1 +CC(NC(=O)C1CCC(=O)N1)c1cccc(OC(F)F)c1 +CCn1c(SCC(=O)N(C)C)nc2ccccc21 +CN1CC(C(=O)N2CCCC2c2noc(C3CC3)n2)CC1=O +CCOc1ccnc(N2CCN(C(=O)c3ccn(C)c(=O)c3)CC2)n1 +CC(C)c1ncc(Cl)c(C(=O)Nc2ccc3c(c2)COC3)n1 +CC(C)c1n[nH]c(C(=O)NC(C)c2ccncc2)c1Br +O=C(Nc1ccc(F)cc1)C(O)c1ccc(F)cc1 +O=C(Cc1ccccc1F)NCCc1nc2c(s1)CCCC2 +Cc1cc(C(=O)OCCc2cn[nH]c2)nn1-c1ccc(F)cc1 +O=C(CN1CCN(c2nccs2)CC1)Nc1ccc2c(c1)OCO2 +COc1ccc(C)cc1-n1nc(CO)c(=O)cc1C +COc1cccc(CCNc2ncnc3[nH]nc(SC)c23)c1 +CC(=O)Nc1ccc(NCC(O)c2ccc(F)c(F)c2)cc1 +CCn1c(SC(C)C(=O)OC)nc2ccccc2c1=O +CCOc1cc(F)ccc1NCc1noc(-c2cccs2)n1 +Cc1ccc(Cl)cc1S(=O)(=O)NCC1(C(N)=O)CCOCC1 +CCN(CC)S(=O)(=O)c1cccnc1N1CCN(CCO)CC1 +COCCOc1ccc(F)cc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C +COC(=O)C1CCCCCC1NS(=O)(=O)c1ccc(F)c(F)c1 +Cc1ccc(C(=O)NCCC(O)c2ccco2)s1 +COCCC(=O)N1CCOC2C(OCc3csc(C)n3)CCC21 +CCOC(=O)Cn1nc(C#N)cc1-c1ccc(CC)cc1 +COc1ccc(N(C)c2ncnc3n[nH]cc23)cc1 +COc1ccc(-n2nnc(C(=O)NC3CCCC3)c2C2CC2)cc1 +CCSc1cc(C(=O)N(C)C2(C#N)CCC2)ccn1 +COCc1nc(C(=O)NC2CCC(O)CC2)cs1 +CCc1cccc(OCC(=O)Nc2c[nH]nc2C)c1 +COc1ccccc1CN1CCCC(CN2CCOCC2)C1 +Cc1nn(CCCOc2ccccc2)c(=O)c(C#N)c1C +Cc1cc(C(C)NC(=O)c2nc3ccccc3c(=O)[nH]2)c(C)s1 +Cn1c(COc2ccc(Cl)cc2)nnc1SCc1ccccn1 +COc1cccc(OCC(=O)N(C)Cc2ccc(F)cc2)c1 +Cc1nc2sc(-c3ccccc3)cc2c(=O)n1CC(N)=O +O=C(Cn1cnc2ccc(Br)cc2c1=O)OCC(F)F +CCCCS(=O)(=O)NCCc1ccc2c(c1)OCO2 +CCCCn1nnnc1NC(=O)NCCN1CCOC1=O +O=C(Nc1ccc2[nH]c(=O)sc2c1)c1ccco1 +COc1cc(NC(=O)CSc2nnc(C)n2C)cc(OC)c1 +CCNC(=O)c1ccc(C)c(NC(=O)Cn2nc(C)c(Cl)c2C)c1 +N#Cc1cccc(-n2ccnc2C2COCCN2)c1 +c1coc(CN2CCOC(c3nccs3)C2)c1 +COc1ccc2cc(NC(=O)c3cc(C4CC4)nn3C)cnc2c1 +CC(NC(=O)NC1(c2cccc(Cl)c2)CC1)C1CCCO1 +Cc1nn2ccccc2c1C(=O)N1CCC(NC(=O)C(C)C)C1 +COc1ccc2cc3c(nc2c1)N(c1ccc(C(N)=O)cc1)CC3 +Cc1ccc(C(=O)OCC(=O)N2CCCCCC2)cn1 +O=S(=O)(NCCn1cccn1)c1ccc(F)cc1 +O=C1CN2C(=N1)N(Cc1ccccc1Cl)c1ccccc12 +Cc1cc(NC(=O)CCOCC2CCCO2)[nH]n1 +O=C(Cc1csc(-n2cccc2)n1)NCc1ccccn1 +Cc1c(C)c2ccc(NC(=O)c3ccc(N(C)C)cc3)cc2[nH]c1=O +CC(C)NC(=O)COCc1cc(-c2ccco2)on1 +O=C(CNC(=O)c1ccccc1N1CCOCC1)Nc1cn[nH]c1 +O=C(Cc1cccc(F)c1)NCCOc1ccccc1 +CCn1c(-c2ccccc2OC)ccc(C#N)c1=O +CC(NC(C(N)=O)c1ccccc1)c1ccc(F)c(Cl)c1 +Cc1ccc(C)c(C(=O)N2CCC(c3ccsc3)CC2)c1 +O=C(Nc1cnn(-c2ccccc2)c1)Nc1cccc2cccnc12 +COc1cc(CNc2nc(C)cc(C3CCC3)n2)ccc1O +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCCc1ccc(C)o1)O2 +Cc1nc(COC(=O)c2ccc(N3CCCC(C(N)=O)C3)cc2)no1 +Cc1cc(C)n(-c2ccccc2NCc2cn(C)nc2C)n1 +CC(C)(C#N)CCSc1nnnn1-c1ccccc1 +CCNC(=O)COc1ccc(NC(=O)c2cn3cccnc3n2)cc1 +CC(O)c1nc2ccccc2n1C(=O)COc1ccc(Cl)cc1 +O=C(c1cc(Br)ccc1F)N1CCc2sccc2C1 +CC(C)CS(=O)(=O)c1ccc2c(c1)NCC(C)(C)O2 +O=C(CCn1ncc2ccccc21)N1CCOCC1 +CC1CCCCC1NS(=O)(=O)c1cccc2nonc12 +Cc1nn(C)c2ncc(C(=O)N3CCC(C)CC3c3ccco3)cc12 +Cc1nnnn1-c1ccc(F)c(NC(=O)C(C)OCC2CCCO2)c1 +Cc1ccc(CN(C)S(=O)(=O)c2cccc(F)c2)o1 +O=C(Cc1c(F)cccc1F)N1CCN(Cc2cccc(O)c2)CC1 +CC(O)CNC(=O)CCC(=O)N1CCc2sccc2C1 +COCc1c(C(=O)Nc2nccs2)nnn1-c1ccc(Cl)cc1 +Cc1ccc(-n2nnc(-c3ccccc3)c2N)cc1C +Cc1cc2nnc(SCC(=O)N3CCCC3)n2c2ccccc12 +CNC(=O)c1cc(NC(=O)NC(C)CO)ccc1F +O=C(c1cc2c([nH]c1=O)CCCCC2)N1CCN(CC2CC2)CC1 +O=c1[nH]c(SCc2cc(=O)n3ccccc3n2)nc2c1CCC2 +Cc1nn(-c2cccc(F)c2)cc1-c1ccnc(N)n1 +CC(C#N)Sc1nnc(-c2ccc(Cl)cc2)[nH]1 +COCCc1noc(-c2cc(C)ccc2Cl)n1 +Cc1cc(NC(=O)c2ccc(OCCOc3ccccc3)cc2)no1 +COCC(=O)N1CCCC1c1nccnc1Nc1nc(C)cs1 +CCCC1CCC(NS(=O)(=O)c2ccc(C(N)=O)cc2)CC1 +COc1ccnc(NC(=O)CCc2nc(C3CCCC3)no2)c1 +CNC(=O)c1cccc(NC(=O)CCC(C)(C)C)c1C +Cc1cccc(NCC(=O)NCC2CN(CC(C)C)CCO2)c1 +O=C(CN1CCc2ccccc21)c1ccc2c(c1)OCCCO2 +CCC(=O)Nc1ccc(-c2ccc(CO)o2)c(OC)c1 +COC(=O)c1ccccc1NC(=O)COc1ccccc1 +Cc1nc(Cc2ccc(OC(C)C)c(N)c2)sc1C +CN(CC(=O)NC1CC1)C(=O)c1occc1-c1ccccc1 +Cc1cc(CN2CCN(C(=O)Nc3ccc(C)c(Cl)c3)CC2)no1 +Cc1cc(=O)n(CC(=O)Nc2cccc(F)c2)c(N2CCCCC2)n1 +COc1cccc(OCC(=O)Nc2nc(C)c(C(C)=O)s2)c1 +O=C(NCc1cccnc1)NC1CCN(c2ccccc2)C1 +COc1ccc(NC(=O)C(C#N)Cc2cccc(OC)c2)cc1 +COc1ccc(NC(=O)CSc2nc(=O)[nH]cc2C)cc1OC +c1ccc(-c2cnnc(N3CCN(c4cnccn4)CC3)n2)cc1 +COCCOCC(=O)Nc1ccc(-c2cc3ccccc3o2)cc1 +CC(C)c1ccc(CN(C)C(=O)CN(C)C(=O)c2ccccc2)cc1 +O=C(NCCC(=O)N1CCOCC1)c1cc(Br)c[nH]1 +CCCc1cnc(C)nc1NCc1cc(N2CCOCC2)ncn1 +CCC(C)N(C)C(=O)Nc1cc2c(cc1Br)OCCO2 +Cc1ccc2ncccc2c1-c1cc(-c2cccnc2)nc(N)c1C#N +Cc1cc(NC(=O)c2cc(-c3cccnc3)on2)c2ncccc2c1 +CC(OC(=O)c1cccn1C)C(=O)C12CC3CC(CC(C3)C1)C2 +NS(=O)(=O)c1ccc(Sc2ccc3c(c2)CCC3)nc1 +Cc1cccc(-c2nnc3c(N)cc(Br)cn23)c1 +COCCS(=O)(=O)NC(C)C12CC3CC(CC(C3)C1)C2 +Cc1ncsc1C(=O)N(C)c1ccc(Br)cc1F +Cc1c(C(=O)NC2CCCC2)sc2nc[nH]c(=O)c12 +CCCn1nnnc1NC(=O)c1sc2ccccc2c1Cl +O=C(NC1CCCCC1)N1CC(S(=O)(=O)c2ccc(F)cc2)C1 +CC(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)Nc1sccc1C#N +COCC(=O)Nc1c(-c2cccc(OC)c2)n[nH]c1C1CC1 +Cc1ccc(S(=O)(=O)NCC(=O)NCC(F)(F)F)c(Cl)c1 +Cc1oc(-c2cccc(Cl)c2)nc1CN(C)Cc1ccncn1 +CCOc1cccc(C(=O)Nc2cc(F)ccc2OC)c1 +Cc1cccc(CC2Oc3cc(N)ccc3NC2=O)c1 +C=CCNC(=O)CSc1nc2ccccc2c(=O)n1C +COC(=O)c1ccc(CSc2nnc(-c3ccoc3C)n2C)cc1 +Cc1ccn2ncc(C(=O)NCCCC(=O)N3CCCC3)c2c1 +O=C(Nc1nc2c(s1)COc1ccccc1-2)C1CC1 +Cc1ccnc(NC(=O)C(C)n2nc(-c3ccccc3)ccc2=O)c1 +COCCN(C)C(=O)CC1Sc2ccccc2NC1=O +CCOC(=O)C1CCN(C(=O)c2cccc(C)c2O)CC1 +COc1ccccc1CC(=O)N1CCC(O)(C(F)(F)F)CC1 +CCC(C#N)OC(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +COc1cc(CN(C)C(=O)CC#N)cc(OC)c1OC +CC(=O)N1CCC(CN(C)C(=O)NCc2ccc(C)cc2N(C)C)C1 +O=C(COc1cc(Cl)ccc1Cl)N1CCOCC1C1CC1 +COc1ccc(C(=O)N(Cc2ccccc2OC)C2CC2)nn1 +Cc1cccc(C(=O)Nc2nnc(-c3ccc(N)cc3)s2)c1 +CC1CC(C)(C)CC(CO)(NC(=O)c2ccon2)C1 +Cc1cc(C2CCCCCN2C(=O)c2ccccc2F)no1 +Nc1onc(Cc2ccc(Cl)cc2)c1-c1ccccn1 +CCOC(=O)CC(C)CNC(=O)c1oc(C)nc1C +O=C1OCCOc2c1cnc1c(C(F)(F)F)cccc21 +Cn1cc(C(C#N)N2CCOCC2)c2ccccc21 +CCCN(CC(F)F)C(=O)CCn1c(C)c(C)sc1=O +Cc1ccc(NC(=O)CSc2nc3ccncc3[nH]2)c(C)c1 +Cc1ccc(OCC(=O)Nc2nc(-c3cccnc3)cs2)c(C)c1 +COc1cccc(Nc2ccnc3c2c(=O)n(C)c(=O)n3C)c1 +Cn1cccc1C(=O)N1CCC2(CC1)CC(Oc1cccnc1)C2 +COc1ccc(OC)c(CN2c3ccccc3C(=O)C23CC3)c1 +CC(C(=O)Nc1cnn(CC(N)=O)c1)c1c(Cl)cccc1Cl +CCCCc1nc(C)sc1C(=O)Nc1ccccc1O +O=C(NC1COC2(CCCCC2)C1)c1cccc(-n2cnnc2)c1 +COC(=O)c1cccc(OCc2nnnn2-c2ccccc2)c1 +CC(=O)NC1CN(S(=O)(=O)Cc2ccccc2)CC1C(C)C +O=C(Cc1cccc2cccnc12)N1CCN(Cc2cccnc2)CC1 +CCCN(Cc1ccc(C#N)cc1)S(=O)(=O)c1ccc(C#N)cc1 +COc1cccc(-c2cc(C(=O)NCCN3CCOC3=O)[nH]n2)c1 +O=C(NCc1cccc(Cl)c1)c1ccc(-c2cccnc2)nc1 +CCNC(=O)c1ccc(OC)c(S(=O)(=O)N2CCCCCC2)c1 +CN(C)C(=O)Cc1nc(CN2CCc3cc(F)ccc3C2)cs1 +Cc1ccccc1C1(CNC(=O)NC(C)C2CCCO2)CCOCC1 +O=S(=O)(c1ccc(CN2CCOC3CCCCC32)cc1)C(F)F +CC(C)(C)Nc1nc(-n2ccnc2)nc(-n2ccnc2)c1Cl +Cc1ccc(OCC(=O)N2CCC(Cn3nc(C)cc3C)CC2)cc1 +O=C1CCSc2c1cccc2C(=O)NC1CCCCC1 +O=C(c1ccc(F)cc1Br)N1CCCCCC1 +Cc1cnc(C(=O)OCc2nc(-c3cccc(Cl)c3)no2)cn1 +O=C1CN=C(Nc2ccc(F)cc2)N1c1ccccc1 +CC(C#N)Oc1ccc(CN2CCC3(C2)OCCO3)cc1 +Cc1nn(C)c(C)c1NC(=O)C(C)OCC1CCCO1 +COC(=O)c1cc2oc(C)cc2n1Cc1ccccc1 +O=C(NCCNC(=O)c1cccc2ncccc12)c1cccnc1 +N#Cc1ccsc1N1CCC(Sc2cccs2)C1=O +O=C(Cc1ccc(F)cc1F)Nc1ccc(OC2CCOC2)cc1 +CC(C)c1c(CO)nnn1-c1cccc2c(O)cccc12 +CCNC(=O)CN1CCN(S(=O)(=O)c2ccccc2C#N)CC1 +Cn1nnnc1SCC(=O)Nc1ncc(Cl)cc1Cl +COc1ccccc1S(=O)(=O)N(C)Cc1ccc(F)cc1 +COC1CCCC1OC(=O)CCNC(=O)C1CCCCC1 +OCc1c(-c2cccnc2)nc2sc(-c3cccnc3)nn12 +COC(=O)c1ccc(C(=O)N2CCc3ccccc32)cn1 +Cc1ccc2oc(C(=O)Nc3ccc(C)c(S(C)(=O)=O)c3)cc2c1 +N#Cc1ncn(Cc2nnc(-c3ccc(Cl)cc3)o2)c1C#N +CCC(C)NC(=O)NCc1c(C)nn(CC)c1C +CC(C)(CO)NC(=O)CCOc1cccc(Cl)c1Cl +CC(C)NC(=O)C1CCCN1S(=O)(=O)c1ccc2ccccc2c1 +O=C(Nc1nc2c3c(ccc2s1)CCCC3)c1cn[nH]n1 +CC1COCCN1C(=O)NCCOc1cccc(Cl)c1 +Cc1cccc(S(=O)C2CCN(C(=O)OC(C)(C)C)CC2)c1 +Cc1cc(C)n2ncc(C(=O)N(C)C(C)C3CC3)c2n1 +COC(=O)CNC(=O)C1CCN(c2cnccn2)CC1 +CCOC(=O)N1CCN(C(=O)c2cc(-c3cccs3)on2)CC1 +CC(C)C(NC(N)=O)C(=O)Nc1cccc(CO)c1 +CCCCS(=O)(=O)c1noc(C(=O)NC(C)C)c1N +COc1ccc(-c2cccc(NS(C)(=O)=O)c2)nn1 +CCC(C)CS(=O)(=O)NCC1(c2ccc(F)cc2F)CC1 +O=C(N1CCOCC1)N(Cc1ccccc1)Cc1ccccc1 +Cc1cccn2c(CN3CCOC(c4nccs4)C3)cnc12 +COC(=O)C1(NC(=O)COc2ccc(C#N)cc2)CCCCC1 +CCOC(=O)C1(C)CCCN(C(=O)OC(C)(C)C)C1 +CC(c1nc(C(C)(C)C)no1)N1CCc2ccccc2C1 +CC(C)(C)OC(=O)n1nnc2cc(Br)ccc21 +CCn1ccc2cc(NC(=O)C(C)OCC3CCCCO3)ccc21 +O=S1(=O)CCCCN1CCc1c(F)cccc1Cl +NC(=O)c1csc(C(=O)Nc2ccc(Cl)c(F)c2)c1 +CC(C)NS(=O)(=O)c1ccc(C(=O)NC2(C#N)CCCCC2)cc1 +CS(=O)(=O)N1CCC(C(=O)N2CCCC2C(N)=O)CC1 +CC1(C)CCC(CNC(=O)Cc2cc3ccccc3[nH]c2=O)CC1 +CCc1onc(C)c1NC(=O)C(CC)Oc1ccccc1F +c1ccc2c(c1)[nH]c1nc(SCC3CCCO3)nnc12 +CNC(Cc1ccc(F)c(F)c1F)C(F)(F)F +Cc1nc(CNC(=O)Nc2ccc3c(c2)CCCC(=O)N3)sc1C +O=c1c(-c2ccccc2)c(N2CCCCCC2)c1=O +CC(=O)NCC1CCN(S(=O)(=O)C(C)C)CC1 +CC1CCC(C)(NC(=O)NCc2cccnc2)CC1 +O=C(CCNC(=O)NCC1CCCO1)NCc1ccccc1 +Cn1ccc2cc(C(=O)N3CCN(CCc4ccccn4)CC3)ccc21 +CC(C)Nc1ncccc1C(=O)NCC1CN2CCCC2CO1 +c1ccc(-c2ccnc(NCCc3nc4c(s3)CCC4)n2)nc1 +COc1c(Cl)c(Cl)c(OC)c(C#N)c1C#N +Cc1cccc(C)c1OCC(=O)N1CCN(C(=O)CO)CC1 +O=C1CC(c2cc3ccccc3o2)c2c(nc3sccn23)CN1 +CCCCOc1cccc(OCC(=O)N2CCN(C)CC2)c1 +CC(O)CC1CCCN1c1cc(N2CCCC2CC(C)O)ncn1 +c1cncc(CNc2cc(-c3nccc4occc34)c3cc[nH]c3n2)c1 +CNC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)CCO2 +CCOC(=O)Cc1csc2nc(-c3ccc(OC)cc3)cn12 +NC(=O)C1(CNC(=O)CSc2ccc(F)cc2)CCOCC1 +COc1ccc(C(N)=O)cc1NCC(=O)Nc1ccccc1C(C)=O +Cc1scc(C(=O)NCc2ccccc2F)c1C +COc1ccc(C(N)=O)cc1NC(=O)c1ccccc1Cl +Cc1ccsc1CNS(=O)(=O)c1ccc(C#N)cc1 +O=C(NCCc1ccco1)c1ncoc1-c1ccc(F)cc1 +Cn1ncc2c(N3CCN(Cc4ccccc4)CC3)ncnc21 +CCN(CCO)C(=O)c1cc2cc(Cl)ccc2[nH]1 +COc1ccccc1OCC(=O)c1ccc(C)cc1 +COc1ccc2c(c1)OC1C2=COc2cc(OC)ccc21 +COc1ccc(C(NC(=O)NCCO)c2nccn2C)cc1 +CN(Cc1ccc(Cl)cc1)Cc1nc2c(cnn2C)c(=O)[nH]1 +COCC(=O)Nc1cccc(-c2ccc3nnc(C)n3n2)c1 +CCN(Cc1cc2cc(C)ccc2[nH]c1=O)S(C)(=O)=O +O=C(NCc1nnc2n1CCC2)c1cccnc1N1CCCC1 +COCCN(Cc1cccnc1)c1nc(C)nc2oc(C)nc12 +O=C(Nc1cnn(-c2ccccc2F)c1)c1cc(=O)c2ccccc2o1 +Cc1ccc(NC(=O)c2nc3c(o2)CN(C(=O)c2cccnc2)C3)cn1 +CC(C)N(C)c1ccc(NC(=O)Cn2cnnn2)cc1F +Cc1cnn(CC2CCCCN2C(=O)c2cccn2C)c1 +NC(=O)C1CCC(C(=O)N2CCCC2CC(=O)c2ccccc2)CC1 +CCOc1ccccc1C(=O)NCCc1csc(-n2cccn2)n1 +CSc1cccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +O=C(NCCN1CCOCC1)c1c2c(cn1-c1ccccc1)CCC2 +CCc1nc2ccccc2n1CC(=O)NCc1ccc(OC)cc1 +Cc1cc(C)c2c(CN3CCOCC3)cc(=O)oc2c1C +CCCOC(=O)Cn1c(CCC)nc2c(N)cccc21 +O=c1cc(-c2cccc(Br)c2)s[nH]1 +Nc1ccc2c(c1)nc(CO)n2Cc1cccnc1N +Cc1[nH]c2c(-c3ccncc3)cnn2c(=O)c1Cc1ccc(C#N)cc1 +Cc1csc2nc(COC(=O)c3cccs3)cc(=O)n12 +CC(C)(C)C(=O)NCC(=O)Nc1nc(-c2ccccc2)ns1 +Cc1cnc2n(c1=O)CC(C(=O)Nc1ccccc1O)CS2 +Cc1c(F)ccc2c1C(C(O)c1ccccc1)NCC2 +CC(C)C(=O)N1CCCC1C(=O)Nc1ccccc1OCC1CC1 +COc1cccc(CN2CCOCC2c2c(C)n[nH]c2C)c1 +CC(=O)Nc1ccc(NC(=O)c2ccc(O)cc2)cc1 +Cn1cc(CN2CCOC3(CCC3)C2)c(-c2ccncc2)n1 +CCNC(=O)c1ccc(NCC(=O)Nc2c(C)cc(C)cc2C)cc1 +COc1ccc(Cl)cc1N(C)C(=O)c1ccncc1 +COCC(=O)N1CCN(Cc2csc(-c3cnn(C)c3)n2)CC1 +CN1C(=O)C2CCC1CN(S(=O)(=O)N(C)Cc1ccccc1)C2 +O=C(OCC(=O)N1CCN(c2ccccc2)CC1)c1cccnc1 +CC(=O)Nc1ccc(F)c(NC(=O)NCCOCC(C)C)c1 +COc1ccccc1NC(=O)CSc1nnc(NC(C)=O)s1 +Cc1cc(CC2COCC2NC(=O)Cc2ccc3c(c2)OCO3)on1 +Cc1ccc(Br)c(NCc2nc(C3CC3)no2)c1 +O=C(Cn1c(-c2ccccn2)nc2ccccc21)Nc1cccc(F)c1 +CCS(=O)(=O)c1ccc(N2CCNC(=O)C2)cc1N +COc1cccc(Nc2nc(SC)ncc2CO)c1 +NC(=O)C1CCN(C(=O)Cc2ccc(OC(F)F)cc2)C1 +CCOc1cc(CNC(=O)C2CC3CCC2O3)ccc1OC(F)F +COCCOCC(=O)Nc1cc(F)c(F)c(F)c1 +COC(=O)c1ccc(NC(=O)N(C)CCc2cccs2)cc1F +O=C(Nc1ccc2c(c1)COC2)c1cn(-c2ccc(F)cc2)nn1 +O=c1nc2n(c(=O)[nH]1)-c1ccccc1Sc1ccccc1-2 +O=S(=O)(NCc1cccc(Cl)c1)c1ccc2c(c1)CCC2 +CNC(=O)CNC(=O)c1cc(C)nc(SC)n1 +CC(Oc1cccc(F)c1)C(=O)NCc1nc2ccc(F)cc2[nH]1 +CS(=O)(=O)Nc1ccc(OC(F)F)c(Cl)c1 +CC(NC(=O)c1cccs1)C(=O)NCc1ccccn1 +Cc1noc(C)c1C1CCCN1S(=O)(=O)c1ccc(Cl)cc1 +CCOc1ccccc1OCCn1c(=O)oc2ccc(N)cc21 +Cc1nnc(C(=O)Nc2cccc(C#N)c2)n1C1CC1 +COC(=O)C1CCCN1Cc1nc(-c2ccccc2C)oc1C +O=C(CC1CC1)N1CCC2C(CCC(=O)N2CCC2=CCCCC2)C1 +Cc1occc1C(=O)N1CCC2(CC1)CNC(=O)C2 +CN(Cc1nccn1C(F)F)C(=O)NCCC1=CCCCC1 +COc1ccc(-c2cc(=O)c3ccc(OC)c(OC)c3o2)cc1OC +C=CCNC(=O)CSc1nnc2n1CCN2c1ccc(F)cc1 +CNC(=O)C1CN(C(=O)c2cccs2)CC12CCCCC2 +Cc1cccc(CC(=O)Nc2ccc(N3CCCCC3=O)c(C)c2)c1 +CCN(CCC#N)C(=O)CN1c2ccccc2CC1C +COc1ccc(Cl)cc1N1CCC(NC(=O)N2CCOCC2)C1 +OCCn1c(C(F)(F)F)nc2cc(Cl)c(Cl)cc21 +CC(C)C(=O)N1CCC2(CC1)Cc1ccccc1C2=O +CN1C(=O)CC(CNC(=O)Nc2cnn(C)c2)C1c1ccccc1 +Nc1cc2c(ncn2C2OC(CO)C(O)C2O)c(=O)n1N +CCOC(=O)c1cc2cnccc2nc1C(F)(F)F +Cc1cccc(NC(=O)c2cc3ccccc3oc2=O)n1 +Cc1ccc(CC(=O)Nc2ccc3c(c2)CCC3)s1 +CC(Cc1ccccc1F)NC(=O)c1cccc(NC(=O)C2CC2)c1 +Cc1noc(C)c1COc1cccc(C(=O)Nc2ncccc2O)c1 +O=S(=O)(c1ccc(CCCCCO)cc1)C1CCCC1 +CCc1cc(C(=O)Nc2nc(-c3cnn(CC)c3C)cs2)cs1 +O=C(Cn1nc2ncccn2c1=O)Nc1ccccc1F +COC(=O)C(C)CN(C)C(=O)C(C)Sc1ccccn1 +O=C(NCC(=O)N1CCCC1)Nc1ccccc1N1CCCC1=O +CSc1nnc(CNc2cc(F)c(F)c(F)c2)s1 +Cc1cc(C(=O)Nc2ccc(Oc3ccc(F)cc3)nc2)nc(C)n1 +CNC(=O)C1CCN(C(=O)c2cccnc2Oc2ccccc2)CC1 +COc1ccccc1C(=O)CNc1cccc(C#N)c1 +CC(C)(C)Oc1cc(CNC(=O)NC2CCc3[nH]ncc3C2)ccn1 +O=C(NC1CC1)N1CCCn2cnc(CO)c2C1 +O=C1OCC(c2ccccc2)N1CCCn1cnnn1 +CCOC(=O)c1cc2c(=O)[nH]c(=O)n(CC3CCCO3)c2nc1C +Cc1cccc(NC(=O)Cn2c(=O)c3cc(C)nn3c3ncccc32)c1 +COC(=O)CCNC(=O)c1cccc(Cl)c1Cl +CCOc1nc(COC)nc(NC(C)CC)c1N +O=C(CCCNC(=O)c1cccs1)Nc1ccc(F)c(F)c1 +C=CCn1c(=O)c(=O)n(CC(=O)N2CCCC2)c2ccccc21 +Cc1cccc(OCCCNC(=O)C2CCN(C(=O)C3CC3)CC2)c1 +CC(C)NC(=O)c1nnc2c(-c3ccco3)ccnn12 +CC(=O)c1ccccc1NC(=O)CCCc1nc2ccccc2s1 +CCOc1ccc(N2CC(C(=O)Nc3nccs3)CC2=O)cc1 +C=CCNC(=O)C(C)Sc1nnc2c(n1)[nH]c1ccccc12 +Cc1sc2nc(-c3ccccn3)c(N)n2c1-c1ccccc1 +CCNC(=O)NC1(C(=O)NCc2nc3ccccc3n2C)CCCC1 +CC(C)CC(C(=O)NCc1ncc(C(C)(C)C)o1)N1CCCCC1=O +CCN(CCO)C(=O)c1cc(C)n(C(C)(C)C)n1 +CCOc1ccc(C(C)NS(=O)(=O)c2cn[nH]c2)cc1 +COc1cc(CNC(=O)c2cc(Br)c[nH]2)ccn1 +CC1NC(=O)COC12CCN(c1ncc(F)cn1)CC2 +Cc1ncsc1CCOC(=O)c1cccc(F)c1 +Cc1cccc(C2(C(=O)N3CCCC(n4cncn4)C3)CCCC2)c1 +N#Cc1ccc(C(=O)NCc2noc(-c3ccco3)n2)cc1 +CC(=O)Nc1ccc(Nc2ncnc(NC(C)C)c2N)cc1 +COc1ccc(C(=O)N2CCN(Cc3nnnn3C3CC3)CC2)cc1 +Cc1ccc(N2CCC(C(=O)NCC(C)(C)C(N)=O)C2=O)cc1 +CCc1cnccc1C(=O)N1CCCC(C(=O)Nc2ccccn2)C1 +Cn1ncc2c(NCCc3n[nH]c(=O)[nH]3)nc(C(C)(C)C)nc21 +O=C(NCCN1CCN(c2ncnc3[nH]ncc23)CC1)C1CCC1 +COc1ccccc1N1CCN(C(=O)C(NC(N)=O)C(C)C)CC1 +COc1ccc(N)cc1-c1n[nH]c(-c2cccc(Cl)c2)n1 +COCCN1CC(C(=O)Nc2ccc(OC)c(Cl)c2)CC1=O +Cc1nnc(N2CCCC2c2ccc3c(c2)OCCO3)c(C#N)c1C +CC(C)(C)C(=O)Nc1ncccc1C(=O)c1ccccc1 +c1ccc(CSc2ccc(-n3cccn3)nn2)nc1 +COc1cccc(-c2nnc3sc(-c4cc(C)on4)nn23)c1 +CC(C)N(Cc1ccccc1)C(=O)c1ccc2c(c1)SCC(=O)N2 +CCCc1ccc2oc(C(=O)N3CCN(CCOC)CC3)c(C)c2c1 +COc1cc(N)ccc1NC(=O)CN(C)c1ccccc1 +CC(C)CCNC(=O)Cn1ncc2ccsc2c1=O +Cc1cc2ncn(CC(=O)NC(C)(C)C)c2cc1C +N#Cc1ccc(CN2CC(n3cccn3)C2)c(F)c1 +Cc1ccc2nc(SCn3nnc4ccccc4c3=O)[nH]c2c1 +CC(NC(N)=O)C(=O)NCC(c1ccc(F)cc1)N1CCOCC1 +CNc1snc(C)c1C(=O)OCc1cn2ccccc2c1C#N +CC(O)CN1CCN(CCOc2ccc3ccccc3c2)CC1 +Cc1ccc(C(=O)NCc2cccc(OCC(F)(F)F)c2)c(=O)[nH]1 +CS(=O)(=O)Nc1cccc(C#CCNC(=O)c2ccsc2)c1 +CCn1cc(-c2cc(-c3sc(C)nc3C)nc(N)c2C#N)cc1C#N +COCCNC(=O)C1(c2cccs2)CCOCC1 +NC(=O)c1ccccc1NC(=O)COc1ccccc1-c1ccccc1 +CCN(CCO)c1ncnc(Nc2ccc(Cl)cn2)c1N +CC(C)Nc1nnc(-c2ccc(C(C)(C)C)[nH]c2=O)s1 +O=C(NCCCCCc1ccccc1)C1CC2CCC1O2 +COc1ccc(OC)c(C(=O)CNc2cccc(F)c2)c1 +COCC(C)NS(=O)(=O)c1ccc(C(C)=O)cc1 +COc1ccc(C2CCN(C(=O)c3ccoc3)CC2)cc1 +CCN(CCc1ccccc1)C(=O)Cn1c(=O)[nH]c2ccccc21 +Cc1ccc(C)c(-n2ccnc2S(=O)(=O)Cc2nnc(C)n2C)c1 +CC1CCCC(C)C1NC(=O)c1ccc(N2CCCCC2=O)cc1 +Cc1nc(N2CCOCC2)c(C#N)c2c1CCCC2 +O=C(CCC1CCCCC1)N1CCOCC1CO +COc1ccccc1CN(C)C(=O)CN(C)c1ncnc2[nH]cnc12 +O=C1CCN(C(=O)c2ccc(-c3cccc(C(F)(F)F)c3)o2)CC1 +O=C(CN1C(=O)CCc2ccccc21)Nc1cccc(-n2cccn2)c1 +CCSc1cc(C(=O)NCC(O)c2ccco2)ccn1 +N#Cc1ccsc1NC(=O)c1cccc(OCC(F)F)n1 +O=C(COc1ccc(F)cc1Br)NCC(O)C1CC1 +O=C(Nc1nc(-c2ccccc2)ns1)c1ccncc1 +Cc1nnc(NC(=O)c2csc3ccccc23)s1 +CC(C)CC1COCCN1CC(=O)N(C)C(C)c1ccccc1 +Cc1nccn1-c1ccc(C(C)NC(=O)NCC2CC=CCC2)cc1 +CC(C)CCNc1ncnc(Nc2ccccc2)c1N +Cc1ccc(Cl)cc1NC(=O)NCCC(=O)OC(C)C +CC(C)C(=O)N1CCCN(C(=O)c2ccccc2)CC1 +CCOCC(=O)N(C)Cc1c(F)cccc1Cl +CCN(C(=O)CSc1nccc(=O)[nH]1)c1cccc(C)c1 +Cc1noc(C)c1CN1CCCCC1c1nc(-c2ccncc2)no1 +Cc1ccc(NC(=O)CN2CCCCCC2=O)c(Cl)c1 +O=c1[nH]c(Cc2ccc(-n3cccn3)cc2)nc2sc3c(c12)CCC3 +Cc1nnc(NC(=O)c2cccc(NC(=O)c3cccnc3)c2)s1 +Cc1nc(CNC(=O)Nc2cccc(F)c2F)cs1 +Cc1oc(C)c(C(=O)NCc2ccc(C(=O)NCC(N)=O)cc2)c1C +COc1c(CNC(=O)Cc2c(C)nn(C(F)F)c2C)c(C)nn1C +Cn1nccc1NC(=O)Cn1ccc(-c2ccc(F)c(F)c2)n1 +CCc1cnc(N2CCC3(CC(Oc4cccnc4)CO3)C2)nc1 +O=C(CN1CCOCC1)NC(Cc1ccsc1)c1nccs1 +CCC1CCC(N(C(=O)C(C)NS(C)(=O)=O)C2CC2)CC1 +O=C(COc1ccc2c(c1)OCO2)NCC(F)(F)F +Cc1cc(C(=O)N(C)C2(C#N)CCC2)nn1-c1ccccc1 +O=c1cccc(-c2cccc(S(=O)(=O)N3CCCC3)c2)[nH]1 +C=CCN(CC=C)C(=O)c1ccc(-n2ccnc2)nc1 +O=C(NCCO)c1nc(-c2ccc3[nH]ccc3c2)no1 +CN(Cc1ccc(Cl)cc1)C(=O)NCc1ncn(C)n1 +CCCN(CC(=O)OC)S(=O)(=O)c1cccc(C)c1 +CCCCc1ccc2nc(-c3nccs3)c(=O)n(C3CC3)c2n1 +FC(F)c1c(Br)ccc2c1OCO2 +CNC(=O)CN1CCN(C(=O)C(C)NC(=O)C2CCCCC2)CC1 +CCOCCC(=O)Nc1nc2ccc(Cl)cc2s1 +O=C(NCCCn1ccnc1)c1cc(F)c(F)cc1Cl +Cc1noc(COC(=O)c2ccc(Br)cc2C)n1 +c1ccc2c(c1)CCCN2CCN1CCOC2(CCOCC2)C1 +CN1CCCN(C(=O)CCOC2CCOCC2)c2ccc(F)cc21 +CC1Nc2ccccc2N(CC(=O)N(C)C2CCCCC2)C1=O +N#Cc1ccc(N2CCC(NC(=O)N3CCc4ccccc43)CC2)nc1 +c1ccc(-c2csc3c4ncnc-4ncn23)cc1 +COc1cc(OC)cc(C(=O)NCC2(N3CCOCC3)CCCC2)c1 +CC(C)Cc1ncc(CNc2ccc3[nH]nc(C(N)=O)c3c2)s1 +CC(=O)c1cccc(OCC(=O)Nc2ccn(C)n2)c1 +COc1ccc(Br)c2c1C(C)NCC2 +Cc1cccc(C(=O)NCC#Cc2ccc(C(=O)N(C)C)cc2)c1 +Cn1ncc2cnn(CC(O)COc3cccc4[nH]ccc34)c2c1=O +COCCCNC(=O)c1sc(Cc2ccccc2)nc1C +CCc1ccc(Cl)c(CC)c1NC(=O)N1CCOC(C(N)=O)C1 +Cc1ccc(C)c(N(C(=O)CCc2cnn(C)c2C)C(C)C)c1 +CCc1nnc(CNc2ccc(N3CCCC3=O)cc2)o1 +COc1ccc(CNC(=O)Nc2nc(C)cs2)cc1OC +NC(=O)C1CCCCN1C(=O)CCSc1cc(F)ccc1F +Cn1c(SCC#N)nc2cc3ccccc3cc2c1=O +CN(Cc1nc2ccccc2s1)C(=O)CN1CCCCCC1=O +CCc1ccc(C(=O)CCC(=O)NC2CCCC2)cc1 +O=C(COC(=O)c1ccc(CO)cc1)Nc1ccccc1 +CC(C#N)Cn1c(-c2ccc(N)cc2)nc2cc3c(cc21)OCO3 +COCc1ccccc1C(=O)OCc1cn(C)nn1 +CC(=O)c1cccc(NC(=O)COC(=O)c2cc3c(s2)CCC3)c1 +Cc1ccc(S(=O)(=O)NC(C#N)c2ccncc2)cc1 +O=C1CC(C(=O)Nc2c(Cl)cccc2Cl)C2(CCCC2)O1 +CCCc1nc(CNc2ccc(C(=O)OC)cc2)cs1 +O=C(C1CCC1)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +CC(C)Oc1ccc(F)cc1NC(=O)N1CCCC1 +CCn1cc(CN(C)S(=O)(=O)c2ccc(C)cc2)cn1 +COc1cc(C)ccc1OCCC(=O)C1CCCC1 +Fc1cc2c(c(F)c1F)CCNC2c1cc[nH]n1 +O=S1(=O)N=C(Nc2ccc(F)cc2F)c2ccccc21 +Cn1c(=O)c2c(ncn2CCc2ccccc2)n(C)c1=O +CCc1nnc(NC(=O)CCC(=O)N2CCc3ccc(C)cc32)s1 +Cc1ccc(NC(=O)c2cccc(NC(N)=O)c2)cc1C +O=C(Cc1ccc2c(c1)OCO2)N1CCc2cc(F)ccc2C1 +CNC(=O)C1(NC(=O)c2nccc3ccccc23)CCCC1 +Cn1cnnc1C1CCN(C(=O)C2Cc3cc(Cl)ccc3O2)CC1 +Cc1cc(Br)ccc1SCC(N)=O +CCCn1c(-c2cccs2)ccc(C(C)=O)c1=O +CC(C)N(Cc1cccnc1)C(=O)CSc1nc2ccccc2o1 +CN(C)c1ccc(NC(=O)c2cccc(OCC(N)=O)c2)cn1 +COc1ccc(Br)c(C(=O)Nc2ccnn2C(C)C)c1 +O=C(Nc1ccc2[nH]ccc2c1)c1ccc2ncsc2c1 +Cc1nc(C)c(C(C)N(C)C(=O)c2c[nH]c3cccc(F)c23)s1 +COCC(=O)N(C)Cc1cc(C)c(OCC(F)(F)F)c(C)c1 +Cc1nc(SCc2cccnc2)c2c(C)c(C)sc2n1 +CCc1nc(CNc2c(C)cccc2CC)cs1 +Cc1cc(C)c(-c2csc(NC(=O)C3CCC(=O)NC3)n2)cc1C +CC1CCC(N(C(=O)c2cccc(OCC(F)F)n2)C2CC2)CC1 +N#Cc1ccc(OCC(=O)c2cnc(N3CCCCC3)s2)cc1 +Cc1ccc(CNC(=O)c2cc(OCc3ccccc3)no2)cc1 +O=C(c1ccc(-n2ccnc2)nc1)N1CCCC1c1ccc(F)cc1 +Cc1ccc(C(=O)NC(C(=O)NCc2ccccc2)C(C)C)cc1 +Cc1ccc(C(=O)Nc2ccc3c4c(cccc24)CC3)cn1 +CNC(=O)c1cc(C)ccc1NC(=O)Cc1coc2cc(C)ccc12 +O=C(c1cccnc1)N(CCc1ccccc1)Cc1ccncc1 +CC(=O)c1cc(C)ccc1OC1CCCCNC1=O +Cc1nn(C)c(C)c1C(=O)Nc1ccc(NS(C)(=O)=O)cc1 +CC(NC(=O)NCCN1CCOCC1)c1ccc(Cl)cc1Cl +CC(=O)N1CCN(C(=O)C(C)(C)c2cccc(Cl)c2)CC1 +CC(Oc1cccc(C#N)c1)C(=O)N1CCc2ccccc21 +COC(C)C(=O)OCc1cc(Cl)c2c(c1)OCO2 +CCCCNC(=O)NCCC(=O)Nc1ccncc1 +COc1ccc(Oc2ccc(NC(=O)N(C)C)cc2)cc1 +CC(C)(C)OC(=O)N1CCNC(c2cc(F)cc(F)c2)C1 +N#CC1(C(=O)Nc2nc3ccccc3s2)CCCCC1 +CC(NC(=O)NCc1ccc2c(c1)OCCO2)c1cccs1 +CCOc1nc(C(C)(C)C)nc(NC2CCCC2)c1N +COc1ccc(CNC(=O)c2cc3c([nH]c2=O)CCCC3)cc1 +Nc1c(NC23CC4CC(CC(C4)C2)C3)ncnc1N1CCOCC1 +CCC(=O)c1c(O)n(-c2ccc(C)cc2)c(=O)[nH]c1=O +Cc1cccc2c1C(C(=O)NC(C)(C)CO)CNC2 +OCCc1cn(Cc2ccccc2)nc1C(F)(F)F +O=C(Nc1ccc(N2CCCC2)nc1)c1cccc(F)c1F +Cc1nc(C(C)(C)NC(=O)c2cccc(F)c2)sc1C +Cn1ccnc(Sc2ncn(-c3ccccc3)n2)c1=O +O=C(NCCCNC(=O)c1cccs1)c1ccc2cc[nH]c2c1 +O=C(Nc1ccc(-n2cncn2)c(F)c1)c1ccc2c(c1)CCO2 +CC(=O)Nc1ccc(NC(=O)c2cccc(N)c2C)cc1 +COCCOCCNC(=O)c1sc2ccc(F)cc2c1C +Cc1ccc(N(C(C)C)S(=O)(=O)c2cnn(C)c2)cc1 +Nc1ccc(NC(=O)c2ccc(F)cc2F)c(Br)c1 +CCc1nc2n(n1)CCCC2NC(=O)CC1OCCc2ccccc21 +COCCNC(=O)Cn1c(=O)c2nnc(C)n2c2ncccc21 +CCc1nnc(NC(=O)CSc2nnc(C(C)C)n2C)s1 +Cc1ccccc1C(C(=O)NCc1nc(C(N)=O)no1)N(C)C +CC(=O)N1CCN(S(=O)(=O)c2cccc(C)c2)CC1 +CC1CC(C)CN(C(=O)NC2CCC(O)CC2)C1 +Cc1csc(SCC(O)c2c(F)cccc2F)n1 +CCOC(=O)c1c(NC(=O)Cn2nc(C)cc2C)sc(C)c1C +O=C(NCC1CCC2C1OCCN2Cc1ccsc1)c1ccco1 +O=C(Cc1ccc(F)cc1F)Nc1ccc2c(c1)C(=O)CCC2 +Cc1ncsc1C(=O)NC(C)CN1CCOCC1 +Cc1cn2nc(NCC3CCOCO3)sc2n1 +CCc1n[nH]c(=O)c(CNC(=O)Nc2nc(C)cs2)c1CC +COc1ccc(C2=NC(=O)C(C#N)C=C2)cc1OC +Cn1nc(-c2ccc(-c3cc[nH]n3)s2)cc1C(F)(F)F +Cc1nc(C)c(C(=O)Nc2ccc(C#N)cc2)s1 +Cc1cccc(OCC(=O)NCC2COc3ccccc3O2)c1 +C#CCN1CCN(CC(=O)NCc2ccc(OC(F)F)cc2)CC1 +CCCn1ccnc1SCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +COc1ccc(OC)c(CN(C)C(=O)c2cccnc2OC)c1 +COCCC1(c2nc(CC(=O)Nc3ccc(F)cc3)no2)CCCC1 +Cc1cc(Cl)ccc1OCCCNC(=O)NCc1ccnn1C +CN(CCOc1ccccc1F)C(=O)NCc1cccc(C#N)c1 +CCN1CC2(CCN(C(=O)c3ccc(OC)nc3OC)CC2)CC1=O +Cc1cc(OCc2nc(-c3ccncc3)no2)ccc1Cl +Cc1cc(Br)cc2c1N(C(=O)C(C)n1cncn1)CCC2 +O=C(NCCc1ccccc1)c1nc(Cn2cc(Cl)cn2)no1 +Nc1ccc(Cl)cc1NC(=O)CCCc1cccs1 +COc1cc(C2NCCc3c2cc(F)c(F)c3F)ccn1 +CC(C)(CO)NC(=O)c1cc(S(=O)(=O)N2CCOCC2)cs1 +COc1cccc(CCNC(C(N)=O)c2ccccc2)c1 +Cc1ccc(S(=O)(=O)N(C)Cc2cccc(F)c2)cc1 +CC1CN(S(=O)(=O)NCc2noc(C(C)(C)C)n2)CCO1 +O=C(CNC(CO)c1ccc(Cl)c(F)c1)N1CCCCC1 +CCn1nnnc1SCC(=O)Nc1ccnn1C1CCCC1 +O=C(Cc1ccc(F)cc1)Nc1ccc(-c2nnc3n2CCC3)cc1 +COc1ccc(NC(=O)Nc2ccc(C(=O)NC3CC3)cc2)cc1 +CCOCCCNC(=O)c1cccc(C(F)(F)F)c1 +O=C(Nc1ccncc1)c1ccccc1OCc1cscn1 +Cc1nc(-c2cc(C(=O)Nc3ccccc3C)n(C)c2)cs1 +CCOC(=O)C(C)NC(=O)c1cc(-c2ccccn2)n[nH]1 +CCn1c(N)nc2cc(C(=O)N3CCC(F)(F)CC3)cnc21 +c1cnn(-c2ccc(CSc3nnc4n3CCCCC4)cc2)c1 +CCn1c(CCNC(=O)NC(C)(CO)C2CC2)nc2ccccc21 +CCOC(=O)Cc1csc(NC(=O)c2n[nH]c3c2CCCC3)n1 +Cc1ccc(CC(=O)NCCC(=O)N2CCCc3ccccc32)cc1 +Cc1cccnc1NC(=O)CCc1c(C)nn(C)c1C +Cc1c(Cl)cccc1NC(=O)c1cc2c([nH]c1=O)CC(C)CC2=O +O=C(NCc1nc[nH]n1)c1ccc(-c2ccccc2Cl)o1 +Cc1cccc(CNC(=O)CNC(=O)OCC(F)(F)F)c1 +COc1ccc(C(=O)c2cc(OC)c(OC)c(OC)c2)cc1OC +O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)C(=O)CCCO2 +O=C(NCc1ccnc2ccccc12)Nc1ccc2c(c1)COC2 +Cc1csc(NC(=O)CSc2nc(-c3ccccc3C)n[nH]2)n1 +Cn1cccc1C(=O)Oc1cccc(NC(=O)C2CC2)c1 +CC(C)n1ccc(Cn2c(=O)c(C#N)cn(C3CC3)c2=O)n1 +O=C(CCc1ccccc1)NCc1cn2ccsc2n1 +O=c1[nH]nc(CN2CCOC(c3ccc(Cl)c(Cl)c3)C2)[nH]1 +O=C(Cc1cccc(F)c1F)Nc1cc(Cl)ccc1-n1cncn1 +Cc1cc(C)cc(C(=O)Nc2ncccc2OCCCC#N)c1 +CCn1nc(C)cc1C(=O)Nc1cc(Cl)cc(Cl)c1 +COc1cc2c(c(OC)c1OC)C(=O)CC(c1ccc(O)cc1)O2 +CC(C)Cc1ccc(S(=O)(=O)Nc2cccnc2)cc1 +O=c1[nH]cc(S(=O)(=O)Nc2cccc(Br)c2)c(=O)[nH]1 +CC(=O)N1CCc2cc(NC(=O)CC(C)c3ccccc3)ccc21 +C=CCNC(=O)Nc1cccc(OCC(=O)Nc2ccccc2)c1 +C#CCNC(=O)c1ccc(NCCc2nccn2C(F)F)nc1 +COc1ccc(-c2cc(C(=O)N(C)Cc3ccco3)[nH]n2)cc1 +COCCNc1ncnc(N2CCCCC2C)c1N +Cn1cnc(CNC(=O)Nc2nnc(Cc3ccccc3F)s2)n1 +NC(=O)N1CCCC(C(=O)NCc2ccccc2Cn2cccn2)C1 +Cc1cc(N)c2onc(CC(=O)Nc3nccs3)c2c1 +CCCNS(=O)(=O)c1ccc(NC(=O)c2cccs2)cc1 +CCC1C(=O)NCCN1Cc1c(C)nn(CC(=O)OC(C)C)c1C +C=CCN1CCC2(CN(C(=O)c3ccc4[nH]ccc4c3)CC2C)C1=O +Cc1ccc(NC(=O)CCCc2nc(C)no2)c(F)c1 +CN(Cc1ccc(O)cc1)C(=O)c1ccc(Cn2cccn2)cc1 +O=C(c1cc(-c2cccc(Cl)c2)[nH]n1)N1CCN(CCO)CC1 +COc1cccc(NC(=O)Oc2ccc3c(c2)ncn3C)c1 +CCN(CC)C(=O)CN(C)S(=O)(=O)c1c(F)cccc1F +CC(=O)c1ccc(NC(=O)NCCC(=O)Nc2ccccc2)cc1C +Cc1cccc(OCCN2CCn3cccc3C2C)c1 +CC(C)Nc1nnc(-c2sc(N(C)C)nc2C2CC2)s1 +Cn1ccnc1SCC(=O)c1ccc2ccccc2c1 +O=C(NCc1nc2ccccc2s1)Nc1ccncc1 +Cc1nn(C)cc1COC(=O)c1cc2ccccc2oc1=O +COCC(=O)Nc1cc(S(=O)(=O)N(C)C)ccc1C +COc1cccc(OCC(=O)Oc2ccccc2C)c1 +CC(C)N1CC(C(=O)NCCSc2ncn[nH]2)CC1=O +CCc1nc2n(n1)CCCC2NC(=O)N(C)Cc1ccc(C#N)cc1 +O=C(N=c1[nH]nc2ccccn12)c1cccc(C(F)(F)F)c1 +Cc1n[nH]c(C)c1C1CCCCCN1C(=O)c1cc(N(C)C)ccn1 +CC(=O)c1ccc(OCCCC(=O)Nc2ccccc2)cc1 +Nn1c(SCC(=O)Nc2ccccc2F)nnc1-c1ccccn1 +CC(=O)NCc1ccc(-c2nc(-c3ccc(O)cc3)sc2C)s1 +Cc1cccc2cnn(CCC(=O)Nc3ccc(F)cc3)c12 +O=C(Cn1nnc(CO)c1-c1ccccc1)Nc1ccccn1 +O=C(NC1CCCCC1)c1nnc2ccc3ccccc3n12 +Cc1ccc2cc(CCNC(=O)C(C)C)c(=O)[nH]c2c1 +NC(=O)C1(CNC(=O)CCn2ccccc2=O)CCOCC1 +CNC(=O)CSc1ccc(C(F)(F)F)cc1N +COCCN(CCC#N)S(=O)(=O)c1cc(C)ccc1F +Cc1nc(CN(C)S(=O)(=O)c2ccc(F)cc2F)cs1 +CCc1sc(C(N)c2cccc(C#N)c2)nc1C +NC(=O)CC1CCN(C(=O)C2COc3ccc(Cl)cc3C2)CC1 +Cc1nocc1-c1[nH]c(C2CCCCC2)nc1C#N +Cc1ccccc1OCCCC(=O)Nc1ccc(C#N)cc1 +CNC(=O)C1(NC(=O)CCc2c(C)n[nH]c2C)CCCCC1 +CC(Cc1cccc(F)c1)C(=O)Nc1nccs1 +O=S(=O)(NCCCO)c1cc(Cl)ccc1Cl +N#CCc1ccc(S(=O)(=O)N2CCc3cc(F)ccc3C2)cc1 +O=C(Nc1ncnc2sccc12)c1ccc2c(c1)CCCC2 +COCCS(=O)(=O)Nc1cc(C(C)(C)C)ccc1O +O=C(CNC(=O)C1CC2CCC1O2)Nc1cccc2cccnc12 +Cc1noc(COc2ccc(N(C)S(C)(=O)=O)cc2)n1 +Cc1cc(C)c(C)c(S(=O)(=O)NC(C)C(=O)N(C)C)c1C +CC(C)(C)CC(=O)NCc1noc(COc2ccccc2)n1 +COc1ccc(CC(=O)Nc2cccc(C)c2C)cc1OC +CSc1cccc(NCc2ccc(O)c(F)c2)c1 +CC(C)CNC(=O)c1cncc(-c2ccc(F)cc2)c1 +Cc1c(C(=O)OCC(=O)N2CCCCCC2)cnn1-c1ccccn1 +CCCCN1CC2(CCCN(C(=O)c3ccc(N)nc3)C2)CCC1=O +COc1ccc2c(c1)CCCN2C(=O)COc1ccc(C(C)=O)cc1 +CC(=O)c1ccc(NC(=O)COc2c(C)cccc2C)cc1 +C=CCN1CCN(C(C)C)C(=O)C12CCN(C(=O)CCOC)C2 +Cc1ccc(OCCS(=O)(=O)c2ccc(N)cc2)cc1C +CCCC1CN(C(=O)C(C)OCCC(C)C)CCO1 +CCOC(=O)C1=C(C)NC(=O)NC1c1ccc(C(F)(F)F)cc1 +O=C(c1cc(-c2ccccc2)no1)N1CCC(O)(CO)CC1 +Cc1cccc(C(=O)OCC(=O)Nc2nccs2)c1 +O=C(CCNC(=O)c1cc2ncsc2[nH]1)Nc1cccc(Cl)c1 +COc1ccccc1CN(C1CC1)S(=O)(=O)c1cccs1 +CCCN(CCc1cccc(F)c1)C(=O)c1cscn1 +Cc1cnc(C(=O)NC(C)c2nc(-c3ccc(Cl)cc3)n[nH]2)cn1 +CCc1noc(-c2cccc(OCC(=O)Nc3ccccc3F)c2)n1 +O=C(NCC1(O)CCOc2ccccc21)c1ccc(F)cc1 +O=C(c1ccccc1-n1cncn1)N1CCNC(c2ccccc2)C1 +Cc1ccc(N)cc1NC(=O)c1cc2c(s1)CCC2 +N#Cc1ccc(NC(=O)CCCNC(=O)c2ccco2)cc1 +CSc1cc(C(=O)Nc2ccccc2C(C)=O)ccn1 +CC(C)(C)NC(=O)COC(=O)c1cc(Cl)ccc1Cl +CC(C(=O)N(C)Cc1cccc(F)c1)S(=O)(=O)c1nncn1C +Cc1ccc(N)c(S(=O)(=O)NCc2ccccc2Cl)c1C +Cc1ccncc1NC(=O)NC1CCN(C(=O)c2ccoc2)CC1 +COc1ccc(NC(=O)CN2CC(c3ccccc3)CC2=O)cc1 +Cc1nc(-c2ccccc2)ccc1C(=O)OCCC(=O)N(C)C +O=C(Nc1ccc(Br)cc1)c1ccccn1 +COc1cc(C)sc1C(=O)Nc1cc(C)ccc1F +COc1cccc(-c2noc(C(=O)NCC(C)C)c2N)c1 +NC(=O)c1ccc(COc2ccc(F)c(Cl)c2)cc1 +COc1ccc(Br)cc1-c1nn(C)c(C)c1N +O=C(NC(c1ccccc1)c1ccccn1)c1ccc2c(c1)OCCO2 +CCCCNc1ccccc1OCC(=O)N1CCOCC1 +Cc1cccc(CCNC(=O)NC(C)(C)c2nc(C)c(C)s2)c1 +Cn1c(NCc2ccc(-n3ccnc3)nc2)c(C#N)c(=O)n(C)c1=O +CC(=O)Nc1ccc2nc(NC(=O)c3cccc(Cl)c3)sc2c1 +COc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1 +O=C(Cc1cccc(F)c1F)Nc1ccc2c(c1)OCO2 +O=C(NCc1ccc(-c2nccs2)cc1)c1ccco1 +Nc1ccc(F)cc1OCC(=O)N1CCOCC1 +CCCS(=O)(=O)NC(C)(C)Cc1ccccc1C +COc1ccc(S(=O)(=O)C2CN(C(C)=O)C2)cc1 +Nc1cc(Br)ccc1S(=O)(=O)NCC1CCCCO1 +CCNC(=O)CN(C)C(=O)c1ccc2ccccc2c1 +O=C(NCc1cccnc1)Nc1cnn(-c2ccccc2F)c1 +Cc1ccc(CN(CCC#N)CCC(F)(F)F)c(C)c1 +COc1ccc(F)cc1C(=O)CNc1c(C)cccc1C +Cc1cc(C(=O)Nc2cc(Cl)ccc2Cl)no1 +Nc1ccc2c(c1)nc1scc(-c3cccnc3)n12 +Cc1cc(O)c2c(C)c(CC(=O)NCc3ccccn3)c(=O)oc2c1 +CSc1cccc(NC(=O)Nc2ccc(F)c(NC(C)=O)c2)c1 +O=S(=O)(NCc1ccccc1OCC(F)(F)F)c1cccnc1 +O=c1c2ccccc2nnn1Cc1nc(-c2ccsc2)no1 +COc1ccc(C)cc1N(CC(=O)NCC(C)C)S(C)(=O)=O +CCCn1c(SCC(=O)Nc2cccc(F)c2)nnc1C(C)C +CCC(C)C(NC(=O)c1cc(S(C)(=O)=O)ccc1Cl)C(N)=O +CC(C)CC(C)N(C)C(=O)c1nc(N)ccc1Cl +CC(C)n1ccc(C(=O)NC2CCN(C(=O)c3ccncc3)CC2)n1 +Cc1cc(C)c(C(O)CCC(=O)NCc2ccco2)c(C)c1 +CC=CCOC(=O)C1CCCCN1S(=O)(=O)c1ccccc1 +Cc1nc(-c2cccs2)sc1C(=O)NCc1cscn1 +CSc1cccc(-c2nnc(NC(=O)c3cccc(F)c3)o2)c1 +Cc1cccc(CNC(=O)c2sc(C)nc2C)c1 +Cc1nnc(N2CCCC3(CN(C(=O)NC4CC4)CCO3)C2)o1 +COCCN(Cc1ccccc1)C(=O)c1cscn1 +CCOC(=O)C(C)(NC(=O)c1cc(C(N)=O)cn1C)C(C)C +CCc1noc(CC)c1CNC(=O)Nc1cccnc1-n1cncn1 +CCCS(=O)(=O)NC(C)c1cccc(S(N)(=O)=O)c1 +Cc1cccc(NC(=O)CCNS(C)(=O)=O)c1 +O=C(Cc1ccc[nH]1)N1CCCC(C(=O)N2CCOCC2)C1 +O=C1CCCC1Sc1nnc(Cc2cccs2)n1C1CC1 +Cc1ccc(CNc2ccc3[nH]nc(C(N)=O)c3c2)s1 +CCN(CCO)C(=O)C1CCN(C(=O)c2ccc(F)cc2F)CC1 +O=C(Cn1nc(-c2cccs2)oc1=O)Nc1ccccc1F +Cc1occc1CN(C)C(=O)NCC(C)N1CCOCC1 +CC1CCc2c(sc3nnn(CCC#N)c(=O)c23)C1 +Cc1c(C(C)NC(=O)CCOC(C)C)oc2ccccc12 +CC(C(=O)NCCc1nc2ccc(F)cc2n1C)c1cccs1 +CCCN(C)C(=O)Cn1c(=O)[nH]c2ccccc2c1=O +O=C(CCC(=O)c1ccc(F)c(F)c1)NCc1ccc(O)c(F)c1 +CCN(CCn1cccn1)Cc1nc2ccccc2c(=O)[nH]1 +CCC(O)CN1CCN(C(=O)c2cc3ccccc3n2CC)CC1 +CC(C)Oc1ccc(CSc2ncc(C#N)c(N)n2)cc1 +c1ccc(-n2nc(C3CC3)nc2-c2ccno2)cc1 +CC(C)COc1cccc(NCc2ccccn2)c1 +COc1ccc2[nH]cc(C(=O)c3cccs3)c2c1 +CCCCc1nnc(NC(=O)Cc2csc(CC)n2)s1 +COCCC(C)(C)C(=O)N1CCC(C(=O)N2CCCCCC2)CC1 +O=C(CN1CCOC(Cn2cccn2)C1)NCCc1cccs1 +Cc1ccc(-n2cc(C(=O)N(C3CCCC3)C3CC3)nn2)cc1 +CCOc1nnc(CN2CCCC(c3nc4ccccc4[nH]3)C2)s1 +CC1(C)Cc2cc(Br)ccc2NC1=O +CCCc1nc(C)c(C(=O)NCCNc2ncccn2)s1 +COc1cccc(OC)c1C(=O)Nc1ccc2c(c1)OCO2 +CSc1ccccc1NC(=O)NCC(=O)NC1CCCCC1 +Cc1ncsc1CCOC(=O)c1cccc(N2CCOC2=O)c1 +Cc1noc(C)c1S(=O)(=O)NCCCn1ccc2cccnc21 +O=C(NCc1nc(-c2ccccc2)no1)c1cc2ccccc2[nH]1 +Cc1ncsc1CCOC(=O)c1ccc(N2CCCCC2=O)cc1 +CC(=O)Nc1ccc(NC(=O)Cc2cccc(Cl)c2)cc1 +CN(CCc1noc(C2CC2)n1)Cc1ccccc1C(F)(F)F +COC(=O)N1CCC(CNC(=O)CC2CCCCC2)CC1 +NC(=O)Nc1cccc(C(=O)OCCc2cccs2)c1 +CCC(C)NC(=O)C(C)NC(=O)Nc1ccc(Br)cc1 +CCNC(=O)c1cccc(CNS(=O)(=O)N(C)C)c1 +Cc1nc2ccc(NC(=O)c3cc(Cl)c[nH]3)cc2s1 +Cc1ccc(CC(NC(=O)C2OCCC2C)c2cccnc2)cc1 +CC(C)n1c(SCC(=O)Nc2nncs2)nnc1C1CC1 +Cc1cc(C(C)NC(=O)Cn2ccccc2=O)c(C)s1 +O=C(NCCCOCc1ccccc1)c1cccc2ncccc12 +COCCNC(=O)c1cc2cc3cc(C)ccc3nc2s1 +CCCC(=O)NCC(=O)N1CCCC1c1nncn1CC(C)C +Cn1c(N2CCOCC2)nnc1S(=O)(=O)Cc1ccccc1 +O=C(c1cccs1)N1CCN(c2nnnn2-c2ccccc2)CC1 +Fc1ccc(-c2cnc(Oc3cccnc3)nc2)cc1 +CC(NC(=O)NCc1ccn(-c2ccc(F)cc2)n1)c1ccco1 +NC(=O)NCc1ccc(NS(=O)(=O)c2ccc(F)c(F)c2)cc1 +COCCn1cc(C(=O)N2CCCC(c3cc(C)[nH]n3)C2)ccc1=O +Cc1ccc(-c2c(NCc3ccc4c(c3)OCO4)c(=O)c2=O)cc1 +Cc1cnn(CC2CCCN2C(=O)c2cc3c(C)nn(C)c3s2)c1 +Cn1c(=O)n(C)c2cc(S(=O)(=O)NC3CCCC3)ccc21 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)c1ccc(C)cc1C +O=c1cc(N2CCCCC2)cnn1CCCn1cnnn1 +Cc1nnc(N2CC3COCC3(COCC3CC3)C2)s1 +COC1CCN(C(=O)Cc2sc(C)nc2-c2ccc(F)cc2)CC1 +CC(NC(N)=O)C(=O)NC1(c2cccc(Cl)c2)CC1 +COc1ccc(OC)c(NC(=O)Oc2ccccc2F)c1 +COc1ccccc1NCC(=O)NCCc1cccs1 +Cc1csc(CCNC(=O)NCCC(C)(C)C)n1 +Cc1cc(C)c(NC(=O)c2cc(C)c(C)c(S(N)(=O)=O)c2)c(C)c1 +Cc1cc2oc(=O)cc(CN(C)Cc3cnn(C)c3)c2cc1C(C)C +O=c1c(Br)coc2ccc(Br)cc12 +CC(=O)c1cc(F)ccc1OCC(=O)NC1CCCCC1C +COc1ccc(CC(=O)NCc2cccs2)cc1OC +NC(=O)c1ccc(NC(=O)CN2CCN(c3ccccc3)C2=O)cc1 +CCCc1cc(C(=O)NC(C)c2ccccc2)[nH]n1 +CC(C)c1ccc(CN(C)C(=O)NCCN2CCOCC2)cc1 +C=CCC(=O)N(C)Cc1ccccc1Br +CC(CNC(=O)CC#N)Oc1ccc(Cl)cc1 +CS(=O)(=O)N1CC2CC(C1)c1cccc(=O)n1C2 +N#Cc1ccc(C(=O)N2CCCC2c2nc3ccccc3s2)cc1 +O=C(COc1ccc(F)cc1)Nc1ccc2c(c1)C(=O)NCCO2 +C=CCNC(=O)N1CCC(OC2CCC(C)CC2)CC1 +Nn1c(SCc2ccccc2)nc2cc(F)ccc2c1=O +COC(=O)CN(C(C)C)S(=O)(=O)c1ccc(O)cc1 +C=CCOc1ccccc1CN1CCN(c2nc(CC)ns2)CC1 +CC(C)(C)OC(=O)N1CCCC(NC(=O)c2cnccn2)C1 +CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)Cc2ccc[nH]2)c1 +CN(CCN1CCOCC1)C(C#N)c1ccc(F)cc1 +COc1cccc(CNS(=O)(=O)c2cccc(C#N)c2)c1 +Cc1cc(CN(C)C(=O)Nc2cc(C#N)ccc2OC(F)F)no1 +CCc1c(C)sc(NC(=O)Cc2ccccc2)c1C(N)=O +CCC1Cn2c(C(=O)NCc3cccnc3)cc3cccc(c32)O1 +CN(CCc1ccccn1)C(=O)CNC(=O)N(C)CC1CCCO1 +CC(C)c1nc(Cn2ccc(-c3ccc(F)cc3)n2)no1 +CC(NC(=O)CSc1ccccc1)c1ccco1 +N#Cc1ccc(CS(=O)(=O)NCc2cn[nH]c2)cc1 +COc1ccccc1NC(=O)COC(=O)c1cc(C)sc1C +N#Cc1cccnc1NCCOC(=O)c1scnc1C1CC1 +O=C(NCC(=O)N1CCOCC1)c1ccc(Cl)cc1 +Cc1cc(N2CCCC(C(=O)NC3CCCC3)C2)n2ncnc2n1 +Cc1cc(N)nn1Cc1ccc(Br)cc1 +COc1ccc(CN(C)C(=O)C(C)(C)C)c(OC)c1 +COc1cccc(C(=O)N2CCCC2Cc2cccc(F)c2)c1F +COc1cccc2c1cc(C(=O)NC1CCCOC1)n2C +Cc1cc(-c2ccncc2)nc2cc3c(cc12)OCO3 +CC(C)(C)c1cc(NC(=O)c2sccc2-n2cnnn2)no1 +CCCC(=O)Nc1sc2c(c1C(=O)OCC)CCN(C(C)=O)C2 +Cn1ccc(-c2nnc(NC(=O)Cc3cccs3)o2)n1 +CCC(NC(=O)c1ccc(Br)cn1)c1ccccc1 +CCCCS(=O)(=O)NCC(=O)Nc1ccc(C)cn1 +CCC(Oc1ccc(C)cc1)C(=O)Nc1cccc(NC(C)=O)c1 +CN(C(=O)CN1CCCC1=O)C1CCc2ccccc21 +Cc1nc(C(C)(C)NC(=O)NC(C)C2CCCO2)sc1C +NC(=O)c1csc(C(=O)Nc2ccc(Oc3ccccc3)cc2)c1 +CCn1c(=NC(=O)c2ccc[nH]2)[nH]c2cc(Br)ccc21 +N#CCCN(Cc1ccccn1)C(=O)c1ccccc1Br +O=C(NC(CN1CCOCC1)c1ccccc1)c1cc(F)cc(F)c1 +FC(F)(F)c1ccnc(N2CCC(c3ccn[nH]3)CC2)n1 +CC1COCCN1C(=O)c1cccnc1S(=O)(=O)C(F)(F)F +CCc1sc(C(=O)Nc2cc(C)ccn2)cc1C +Cc1cc(C(=O)NCC(=O)Nc2ccc3nc(C)sc3c2)n(C)n1 +N#CCCCn1c(-c2nonc2N)nc2ccccc21 +NC(=O)C1CCN(C(=O)c2cccc(-n3cccn3)n2)c2ccccc21 +Cc1c(Br)cccc1CNC(C)(C)C(=O)N(C)C +O=C(Nc1ccccc1Cl)c1cc2ccccc2[nH]c1=O +Cn1cc(C(N)=O)cc1C(=O)Nc1cnc(-c2ccccc2)nc1 +Cc1cc2c(cc(C(=O)NCc3cccs3)n2C)s1 +COC(=O)c1coc(C(=O)NCC2(c3ccncc3)CC2)c1 +COc1ccc(NC(=O)CCc2ccccn2)cc1F +Cc1ccc(-c2ncc(C(=O)NCCS(N)(=O)=O)s2)c(C)c1 +CNS(=O)(=O)c1ccccc1NCCNC(C)=O +CN(C)S(=O)(=O)c1ccc(SCC(=O)NCCC#N)nc1 +Cc1ccc(C(C)Nc2nnnn2-c2ccccc2)s1 +C=CCCC(=O)Nc1ccc(C)c(S(N)(=O)=O)c1 +CN(CCc1ccccc1)C(=O)Cn1c(=O)[nH]c2ccccc21 +COC(=O)c1cc(NC(=O)c2ccc(F)c(F)c2)cc(C(=O)OC)c1 +Cc1cc(NC(=O)CNc2ccc(C(=O)NC(C)CO)cc2)n(C)n1 +CCOc1ccccc1CNC(=O)Cn1sc2ccccc2c1=O +N#Cc1ccc(COC(=O)c2cccc(-n3cccn3)n2)cc1 +Cc1cc2c(cc3c(=O)n(CC(=O)NC4CCCC4)ncn32)s1 +Cc1nc2c(cnn2C(C)C)cc1-c1nc(-c2ccc(C#N)cn2)no1 +CCC(C)Oc1ccc(-c2cn[nH]c(=O)c2CO)cc1 +COC(=O)Nc1ccc(CNC(=O)N2CCC2)cc1 +CCOCCC(=O)Nc1cnn(-c2ccccc2)c1 +CCc1ccc(C(=O)NCCC(=O)NC2CCCC2)o1 +CC1CN(Cc2cn3cc(Cl)ccc3n2)CCO1 +C=CCNC(=O)N1CCC(C(=O)NCC(F)(F)F)CC1 +CCCC(=O)Nc1cccc(CNC(=O)NCC(=O)N2CCCC2)c1 +Cc1cc(C(=O)Nc2nc(Cc3ccccc3)cs2)on1 +COc1ccc(CNc2cccc(C#N)c2)cc1F +Cc1ccc(S(=O)(=O)CCC(=O)OC(C)C(N)=O)cc1 +CC(C)C(C(C#N)c1ccccc1)N1CCOCC1 +CCC(=O)Nc1cccc(NCc2cc(=O)n3ccsc3n2)c1C +N#CCC(O)CCc1ccc(Br)cc1 +Cc1cc(C)n(CCC(=O)NCCc2ccccn2)n1 +c1ccc(CSc2ncnc3ccccc23)nc1 +COc1ccc(C(=O)Nc2ccc(-c3nccs3)cc2)cc1OC +Cc1ccc(S(=O)(=O)n2ccc(C(=O)NC3CCOCC3)c2)cc1 +Cc1cccc(CNC(=O)COC(=O)c2ccc(F)cc2)c1 +CCCCN(CC(N)=O)c1ccc(F)cc1CO +CC(C)(C)NC(=O)Cn1cnc2nc(N3CCCCC3)sc2c1=O +CCCn1c(SCc2noc3c2CCCC3)n[nH]c1=O +CC(C)CC1COCCN1C(=O)c1cnn(-c2cccc(Cl)c2)c1 +COc1ccc(C(=O)N2CCCC2C(=O)NC2CC2)c(F)c1 +Cn1cc(CNC(=O)c2sccc2-n2cnnn2)cn1 +Cc1ccc2nc3c(c(C(=O)N4CCOCC4)c2c1)CCCC3 +Cc1c(C(C)NC(=O)CC(C)(C)C)cnn1-c1ccc(F)cc1 +COc1ccccc1Oc1ncnc(NCc2ccccc2)c1N +CC(C(=O)N1CCCCCC1)n1nnc2ccccc2c1=O +COC(=O)c1cccc(NC(=O)CSc2nnnn2C)c1 +CC(=O)NCCNC(=O)N(C)C1CCCCCC1 +Cn1nncc1CNc1ccccc1-n1cccn1 +CN(C(=O)COc1cccc(CO)c1)c1ccccc1 +CCS(=O)(=O)N1CCn2c(CNC(=O)C3CC3)cnc2C1 +Cc1c[nH]c(=O)n1-c1cccc(NC(=O)N2CC3CC=CCC3C2)c1 +Cc1cccc2c1cnn2CCCNC(=O)c1cccc(C#N)c1 +COc1cc2nc3cc(N)c(OC)cc3nc2cc1N +CC1CN(CCn2cc(N)ccc2=O)C(C)CO1 +CC(C)OC(=O)C(C)n1nc(CO)cc1-c1ccccc1 +Cc1nc(N(C)Cc2ccc3nonc3c2)c2nc(C)oc2n1 +COc1cc(CNC(=O)OC(C)(C)C)cnc1OC +Cc1noc(C)c1CN(C)C(=O)c1ccn(C)c(=O)c1 +CSc1cc2c(cc1NC(=O)NC1CCCC1)OCCO2 +O=C(Cc1ccccc1)Nc1nc2c(s1)COCC2 +CC(NC(=O)CSc1nnc(C(C)(C)C)o1)C(=O)N(C)C +O=C1NC2(CCN(C(=O)C3CCC3)CC2)Nc2cc(Cl)ccc21 +Cc1nc(CNc2nnc(CCC(C)C)o2)cs1 +COc1ccc(CCCNC(=O)N2CCC(C(N)=O)CC2)cc1OC +Cc1cnc2n(c1=O)CC(C(=O)Nc1ccc(F)cc1F)CS2 +Cc1ccc(-n2nc(C)nc2C(C)(O)c2ccccc2)cc1 +CC(=O)N1CCN(C)CC1C(=O)N1CCC(Cc2cccnn2)CC1 +CC1CCCC(NC(=O)c2cccc(C#N)c2)C1C +O=C(Nc1cc(Cl)cc(Cl)c1)c1cnc2n(c1=O)CCS2 +Cc1csc(C(C#N)C(=O)CCC(=O)Nc2nccs2)n1 +COC(=O)CN(C(=O)c1cccc(OC)c1)C(C)C +COc1ccc(S(=O)(=O)NCCc2ccc(F)cc2)c(OC)c1 +O=C(CC(F)(F)F)Nc1ccc(Sc2nncs2)cc1 +Cn1c(N)c(C(=O)CSc2ccc(Cl)cc2)c(=O)n(C)c1=O +CCOc1cccc(CNC(=O)c2cnc3n(c2=O)CCS3)c1 +O=C(NCc1ccc2c(c1)OCO2)N1CCCC1c1ccncc1 +N#CC1(C(=O)Nc2cccc(CN3CCOCC3)c2)CCCC1 +COc1cccc(C(=O)NCc2c(C)nc3sc(C)nn23)c1OC +Cc1ccccc1Oc1ncccc1CNC(=O)CCn1cncn1 +COc1ccnc(Sc2nc(C3CC3)n(-c3ccccc3)n2)n1 +CCOc1cc(N)cnc1Nc1ccc(C(=O)OC)cc1 +N#Cc1ccc(C(=O)NCC(=O)N2CCCc3cc(F)ccc32)cc1 +COc1ccc(CN(C)Cc2ccccc2Br)cn1 +COc1cc(CNc2cccc(OC(C)C)c2)ccc1O +CCC1CCC(NC(=O)CCCc2nc(C(C)C)no2)CC1 +Cc1cc(C(=O)NC(C)c2cccc(Cl)c2)on1 +CCn1cnnc1CNC(=O)c1cc(-c2ccc(F)cc2)c(C)s1 +CC(C)Oc1ncc(OC2CC2)cc1C(=O)N(C)C +Cc1cccc(Cn2nc(C)cc2NC(=O)c2cc(C)[nH]c(=O)c2)c1 +Cc1cccnc1NC(=O)C1CCCN1C(=O)c1ccco1 +CN(C)C(=O)CCc1cccc(NC(=O)c2cccnc2)c1 +Cn1cc(C(=O)Nc2ccccc2C2CC2C2CC2)c(C(F)F)n1 +CCCCNS(=O)(=O)c1cnc(N)c(Cl)c1 +Cc1ccc2oc(-c3nnc(C(=O)NC4CCCC4)o3)c(C)c2c1 +CC(C)CCOC(C)C(=O)Oc1ccc2ccc(=O)oc2c1 +CCc1cnc(CN(C)C(=O)c2scnc2C2CC2)s1 +COc1c(F)cc(NC(=O)c2c(F)cccc2F)cc1F +COCC(=O)N1CCN(CCn2c(=O)oc3ccccc32)CC1 +COCCCNC(=O)NC1CCCc2c1cnn2Cc1ccccc1 +CC(C)N(C(=O)c1cnc2ccc(F)cc2c1)c1cccnc1 +COc1cccc(CCNC(=O)Cn2cnc(C(C)C)cc2=O)c1 +O=C(Nc1cccc(C(F)(F)F)c1)c1cccnn1 +Cc1nc(N2CCN(Cc3csc(C)n3)CC2)c2sccc2n1 +Cc1nn(C)c(C)c1CC(=O)N(C)C1CCCCC1 +Cc1ccc(NS(=O)(=O)c2cccc(S(N)(=O)=O)c2)c(C)c1 +OC(CNCc1ccc2c(c1)OCO2)c1ccccc1 +COc1ccc(CCC2CCN(C(=O)Nc3cnn(C)c3)CC2)cc1 +CN(CCOCC1CC1)CC1=NS(=O)(=O)c2ccccc2N1 +Cc1ccnc(NC(=O)CCC(=O)c2cc(C)ccc2C)c1 +COc1ccc(CCNC(=O)c2ccc3c(c2)OCO3)cc1OC +O=C(NCC1CCCO1)c1cc(-c2cccnc2)[nH]n1 +O=C(NCCOc1ccc(F)cc1)NC1CCCCC1 +CCN(CC(C)C#N)C(=O)C(C)Sc1nncn1C +O=C(Nc1ccc(OC(F)(F)F)cc1)C1CCCN1C(=O)C1CC1 +CCCn1nc(C)c2c(C(F)(F)F)cc(=O)oc21 +CCOC(=O)N1CCC2(CC1)C(=O)N(CO)CN2c1ccccc1 +CC(CNC(=O)c1ccncc1)Oc1ccccc1 +Nc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1 +Nc1cc(=O)[nH]c(SCc2cn3cccnc3n2)n1 +CC(OCC1CCCO1)C(=O)NC(C)c1ccc(-n2cncn2)cc1 +CCOc1ccc(CCNCc2ccco2)cc1N +Cc1ccc2c(NC(=O)c3c[nH]c4ccccc34)cccc2n1 +Cc1cc(NC(=O)CC2OC(=O)c3ccccc32)n(C)n1 +CC(=O)c1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1 +CCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)CC +NS(=O)(=O)c1ccc(CCNC(=O)c2cc3ncccn3n2)cc1 +Cc1ncsc1CNC(=O)NC(C)c1ccc(F)c(F)c1 +O=C(NCc1cccnc1)NC1CCCCc2ccccc21 +O=C(Nc1cccc(Cl)c1)C1Nc2ccccc2S(=O)(=O)N1 +Cn1cc(Cc2cc(O)nn2C)c(-c2ccc(F)cc2)n1 +COCCOCC1NCCc2ccc(C(=O)OC)cc21 +CC(=O)Nc1cccc(NC(=O)NC(C)c2ccc(F)c(Cl)c2)c1 +O=C(c1ccccc1)C1CCN(CC(F)(F)C(F)F)CC1 +CCc1ccc(OC)c(-c2cc(NC3CC3)ncn2)c1 +CC1CCCCC1NC(=O)Cn1nc(-c2ccc(F)cc2)ccc1=O +CC(C)N(CC(N)=O)c1ccc(S(=O)(=O)N2CCCC2)cn1 +CC1CCCCN1C(=O)c1ccc2ncsc2c1 +Nc1cccc(Cn2cnc3cc(C(F)(F)F)ccc32)c1 +CC(O)c1cccc(OCC(=O)N(C)CC(F)(F)F)c1 +Cc1cccc(OC(=O)C2CCN(C(=O)N3CCCC3)CC2)c1 +CC1CC1C(=O)Nc1nnc(C2CCCCC2)s1 +O=S(=O)(C1CC1)N1CCC2(CC1)CN(CC1CC1)c1ccccc12 +Cc1nn(C)c(C)c1S(=O)(=O)NC1CCC(O)CC1 +O=C(NCC(=O)N(Cc1ccco1)Cc1ccco1)c1cccs1 +Cc1ccc(S(=O)(=O)N(CCC#N)C(C)C)cc1C +Cc1ccn2c(=NC(=O)CCCc3nc(C4CC4)no3)[nH]nc2c1 +CC1CN(Cc2ccsc2)C(c2ccccc2)CO1 +CCCn1ccnc1SCC(=O)C(C#N)c1nc(C)cs1 +CC1(C)CC(NC(=O)CCn2c(=O)[nH]c3ccccc3c2=O)CCO1 +CCN(C(=O)CNc1cccc(NC(C)=O)c1)C1CC1 +CCCNC1=NS(=O)(=O)c2c(Cl)cc(Cl)cc2N1 +CCNc1nnc(-c2cc(-c3cccnc3)oc2CC)s1 +N#Cc1ccc(Cn2ccnc2CC(F)(F)F)cc1 +CC(=O)N1CCN(C(=O)Cn2nc(-c3ccccc3)ccc2=O)CC1 +CCOC(=O)CC(C)CNC(=O)Nc1cc(F)c(F)cc1F +Cn1cc(CCOC(=O)c2nn(-c3ccccc3)c3c2CCC3)cn1 +CC1(C)CCCN1C(=O)c1cc2ccccc2oc1=O +COC(=O)CN1CCC(Nc2cc(OC)ccc2C)CC1 +FC(F)(F)c1ccnc(NCc2cccnc2-n2ccnc2)c1 +COc1ccccc1OCc1nc(C2CC2)c(C(C)=O)s1 +Cc1cc(C(=O)Nc2nc(-c3ccc(C)c(C)c3)cs2)ncn1 +CNS(=O)(=O)c1ccc(C(=O)Nc2cc(C)ccc2F)o1 +CCCN(C(C)=O)c1ccc(NC(=O)Nc2ccccc2)cn1 +c1ccn2c(Sc3ccc4nnnn4n3)ncc2c1 +O=C(CCCc1nc2ccccc2s1)N1CCC2(CC1)OCCO2 +COc1ccccc1N1CCC(NC(=O)c2cccc(OC)c2F)C1 +CCn1c(C)cc(C(=O)CSc2nc(N)cc(N)n2)c1C +CC(=O)c1cc(Br)c(N2CCOCC2)o1 +O=C(c1ccc(N2CCCC2)cc1)c1ccc2c(c1)OCCO2 +CCN1CC(C(=O)N2CCC(c3cccc(C#N)c3)CC2)CC1=O +COc1cc(OC)cc(C(=O)NCCc2cccc(F)c2)c1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(OC)c(F)c1 +Nc1ccc(C(=O)Nc2cc(Cl)cc(Cl)c2)cc1 +Cn1cc(CNC(=O)Nc2ccc3[nH]c(C(F)F)nc3c2)cn1 +CCCCN(C)C(=O)Nc1ccc(C(=O)NC2CC2)cc1 +CCn1c(SCC#N)nnc1-c1ccc(OC)cc1 +CCNC(=O)CNC(=O)c1cc(Br)cn1C(C)C +CCN(Cc1cnc2ccccn12)C(=O)c1cc(-c2ccccc2)n[nH]1 +O=C(CSc1ccccc1)N1CCN(CCc2ccccc2)CC1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc3c(c2)OCCO3)CC1 +O=C(CO)N1CCN(C(=O)Cc2coc(-c3ccccc3)n2)CC1 +CC(C)N(C)C(=O)c1occc1COc1ccccc1 +Cc1nn(CC(C)C(=O)NCC2CC2)c(C)c1Br +O=C(COc1ccc(F)cc1)Nc1ccc(N2CCOCC2)nc1 +O=C(NC1CC1c1cccc(Cl)c1)c1ccsc1 +Cc1sc2ncnc(-n3cnc(C#N)n3)c2c1C +CCOc1ccc(NC(=O)NCc2ccccc2OC)cc1 +CN(C(=O)Nc1ccccc1-n1cccn1)C1CCCCC1 +CCS(=O)(=O)N1CCCN(C(=O)c2ccc(F)cc2)CC1 +NC(=O)NCC(=O)NCc1cccc(OCc2ccccn2)c1 +C=CCNc1nnc(SCc2cc(C)on2)s1 +CCC(C)NC(=O)c1cnn(-c2ccc(C)cc2)c1-n1cccc1 +Cc1nc(C)c(CCNC(=O)NC(C)c2c(C)noc2C)s1 +c1csc(C(Nc2ccc3nnnn3n2)c2cccs2)c1 +CC(C)n1cccc1C(=O)OCc1cncs1 +CC(=O)c1ccc(NC(=O)CSc2nnc(C)n2C2CC2)cc1 +COc1ccc(C(=O)N2CCCCCC2)cc1Cl +COc1ccccc1Cn1c2cc(C)sc2c2cn[nH]c(=O)c21 +CC(C)c1n[nH]c(SCC(=O)c2c[nH]c3ccccc23)n1 +CCOc1ncccc1NC(=O)Cc1ccc2c(c1)OCCO2 +COc1ccc(Oc2cc(CNC(=O)c3ccc[nH]3)ccn2)cc1 +Cc1nnc(SCC(=O)Nc2ccc(F)cc2F)n1N +CCOc1ccc(-c2cc(C(=O)Nc3cccc(C#N)c3)n[nH]2)cc1 +CCN(CCO)S(=O)(=O)c1ccc(Cl)cc1 +CCn1cc(CNC(=O)C2CCCN2C(=O)OC(C)(C)C)cn1 +N#Cc1ccc(NCC(=O)N2CCOCC2C2CC2)cc1 +CN(C(C#N)c1ccncc1)S(=O)(=O)c1ccccc1 +COc1cc(OC)cc(C(=O)c2ccccc2OC(C)=O)c1 +Oc1ccc2c(c1)C(c1ccccc1Cl)NCC2 +COC(=O)c1c(C)oc2cc(Br)c(OCC(N)=O)cc12 +Oc1cc2c(cc1Cl)CCNC2c1ccccn1 +O=C(CCCOc1ccccc1F)NCc1cscn1 +COC(=O)C(C)N(C1CC1)S(=O)(=O)c1ccc(SC)cc1 +Cc1ccn(Cc2noc(-c3ccccc3Cl)n2)c(=O)c1 +C#CCOc1ccccc1CN1CCOCC1c1ccc(C)o1 +CCCn1c(C)nnc1SC(C)C(=O)N1CCCCC1CC +CC(C)c1ccsc1C(=O)N(C)Cc1cccnc1 +CNS(=O)(=O)Cc1ccc(CNC(=O)c2ccc(=O)[nH]c2)cc1 +Nc1ccc(NC(=O)c2ccccc2Cl)c(Cl)c1 +Cc1nc(C)c(-c2nccn2-c2ccc3cn[nH]c3c2)s1 +CC(C)(NC(=O)C1CCOCC1)c1cccc(F)c1 +Cc1ccc(Cl)cc1S(=O)(=O)NCC(C)(O)c1cccs1 +Cn1cc(NC(=O)CCCN2CCOC2=O)cn1 +CCc1ccc(C(=O)CSc2nncn2C)cc1 +O=C(CCNC(=O)N(Cc1ccc(F)cc1)C1CC1)NC1CCCC1 +O=C(CCC1CCCO1)N1CCCCC1Cn1cccn1 +CCOC(=O)C1CCN(C(=O)c2cc(-c3ccc(F)cc3)n[nH]2)CC1 +CCCC1CN(Cc2ccccc2OCC(=O)N(C)C)CCO1 +COc1ccc(NC(=O)CNc2ccc(F)cc2F)cc1 +CC1CC1C(=O)NCCC(=O)Nc1ccccc1C(=O)N(C)C +COc1ccc(OC)c(C(=O)CNc2cccc(C#N)c2)c1 +O=C(Nc1ccncc1)N1CCCCC1c1cc2ccccc2[nH]1 +CC(=O)c1cccc(NC(=O)NC2(c3ccccc3)CCOCC2)c1 +Cc1c(-c2nc3ncccc3o2)cccc1-n1cnnc1 +COc1ccc(C(=O)NCCNC(=O)C2CC(=O)N(C(C)C)C2)cc1 +COc1cc(CNc2cnn(-c3ncccn3)c2)cc2c1OCO2 +COc1cccc(-c2c(C)c(C)nc3ncnc(N)c23)c1 +CC(C)(C)c1ccc(C(=O)NCCCS(N)(=O)=O)s1 +O=C(NCc1cc(C2CC2)[nH]n1)c1ccc(NC(=O)C2CCC2)cc1 +COc1ccc(-n2nc(C(F)(F)F)cc2C2CC2)cc1 +O=C(Cc1ccon1)N1CCN(c2ccc(F)cc2Cl)CC1 +CC(OCc1ccccc1)C(=O)NCC(C)N1CCOCC1 +O=C(NCc1ccncc1)NCc1nc2ccccc2s1 +CCCNC(=O)CN1CCN(c2ncnc3cc(Cl)ccc23)CC1 +CCOc1cccc(CNC(=O)CCn2cncn2)c1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)Nc2ncc(C)s2)c1 +Cc1cn2nc(NC3CCN(C(=O)C4CCCCC4)CC3)sc2n1 +CC(C)(C)OC(=O)Nc1cc2c(cc1N)OCO2 +COC(=O)NCC(=O)N1CCCC(COc2ccc(F)cc2)C1 +CCOC(=O)C(N)c1nnc(SC)n1C1CC1 +Cc1nccc(-c2nc3cc(F)ccc3c(=O)[nH]2)n1 +OCc1nnc(SCc2ncc(-c3ccccc3)o2)n1C1CC1 +CCOC(=O)N1CCN(CCc2ccccn2)CC1 +CCCNC(=O)CNc1cc(Cl)ccc1C(=O)N(C)C +CC(NC(=O)CN(C)c1ccc(N)cn1)c1ccccc1 +COC(=O)c1ccc(C(=O)Nc2onc3c2CCC3)cc1 +O=S(=O)(c1ccc(Br)cc1)N1CCNCC1 +CC(C)Oc1ccc(F)cc1C(=O)c1ccc(N)cc1 +CCN(CC)S(=O)(=O)c1cc(C(=O)OC)ccc1F +c1ccc(-c2n[nH]cc2CN2CCC3(C2)OCCO3)cc1 +CCCc1noc(C2CCCN(C(=O)c3ccc(OC)cc3)C2)n1 +O=C(NC1CCN(C(=O)Cc2ccc[nH]2)CC1)c1ccccc1F +COC(=O)c1cccc(S(=O)(=O)N=c2cccc[nH]2)c1 +CC(C)(O)c1nc2ccccc2n1CC(=O)N1CCCCCC1 +CCOCC(=O)Nc1ccc2c(c1)CCC(=O)N2CCOC +CCOc1ccc(C(=O)NCC(=O)N2CCCCC2C)cc1OCC +Cc1noc(C)c1CCC(=O)Oc1ccc(F)cc1 +COc1cccc(Oc2ccc(CNC(=O)CC(C)C)cn2)c1 +CC(NC(=O)c1cc(C(N)=O)cs1)c1ccc(C#N)cc1 +O=C(Nc1nnc(CCSc2ccccc2)o1)c1ccc(F)cc1 +CCOc1ccccc1OS(=O)(=O)c1ccc(C#N)c(Cl)c1 +CC(CNC(=O)N1CCCC(CO)C1)c1ccc(F)cc1F +CC(NS(N)(=O)=O)c1ccc(Cl)c(Cl)c1 +COCCC(=O)N1CCC(C(N)=O)c2ccccc21 +CCN(CC(=O)NC(C)C)S(=O)(=O)c1cccs1 +CN(C)C(=O)CNC(=O)c1nc(-c2ccccc2)oc1C1CC1 +CC(CCOc1ccccc1)C(=O)NCc1cnn(C)c1 +Cc1cccc(OCC(C)NC(=O)Cc2csc(C)n2)c1 +CCSc1ccc(NC(=O)NC(C)c2c(C)nn(C)c2C)cn1 +COC(=O)Cc1ccc(-n2ncc3c2CCCC3=O)cc1 +Cc1cc(CNC(=O)CCNS(C)(=O)=O)ccc1F +Cc1cc(N)n(-c2ccc(-c3cccs3)nn2)n1 +O=C(CCc1nnc(-c2ccsc2)o1)NCc1cscn1 +Cc1cc2c(cc3c(=O)n(CCCC#N)nc(C)n32)o1 +Cn1cnc(S(=O)(=O)N2CCCC2c2ccccn2)c1 +Cc1n[nH]cc1CNC(CC(F)(F)F)c1ccc(F)cc1 +CC(=O)Nc1ccc(NCc2cccc(C(N)=O)c2)cc1 +O=C1CC(C(=O)N(Cc2cccs2)C2CC2)CN1Cc1ccco1 +Cc1cc2c(cc1F)C(c1ccc(N)cc1)NCC2 +CNS(=O)(=O)c1ccc(C(=O)Nc2cccc(-n3cnnc3)c2)o1 +O=C1CCC(C(=O)N(Cc2c(F)cccc2Cl)C2CC2)N1 +CS(=O)(=O)c1ccc(SCC(=O)N2CCOCC2)cc1 +CCCc1c(C(=O)Nc2ccncc2)[nH]c(C)c1C(=O)OC +CC(CCc1ccccc1)Sc1nnc(CN2CCCC2=O)o1 +CC1CCN(C(=O)c2cnc3sc4c(n3c2=O)CCCC4)CC1 +N#Cc1ccccc1OCc1ccc(C(N)=O)cc1 +CCC(=O)N1CCCCC1C(=O)OC(C)COc1cccc(F)c1 +CCCOc1cc(CO)cc2c1OC(C)(C)C(=O)N2C(C)C +Cc1cnn(-c2ccc(C(=O)NCC3CC3C)cc2)c1 +Cc1ccc(C2(O)CCN(c3cc(C)ncn3)CC2)cc1 +COc1ccc(C(=O)NCCO)cc1OC(F)F +Nc1cc(C(F)(F)F)ccc1SCC(F)F +O=C(NCCc1ccc(O)cc1)c1ccc(O)c(Cl)c1 +O=C(CCCc1nc2cccnc2n1-c1ccccc1)NC1CCCC1 +CC(CNC(=O)NCCn1cccc1)Nc1ccccc1 +Nc1cc(NC2(CO)CCCC2)cc(S(N)(=O)=O)c1 +COC(=O)CN1C(=O)CNc2cc(OC)ccc21 +CN(CC(=O)N1CCOCC1)C(=O)c1ccco1 +CCOC(=O)N1CCN(C(=O)CCC(C)O)CC1 +O=C(NCC1CCCCO1)c1ccc2[nH]c(=O)[nH]c2c1 +O=C(NCc1ccccc1)Nc1nnc(CC2CCCC2)s1 +N#CCCN(CCC(F)(F)F)C(=O)c1ccc(C(F)(F)F)cc1 +CCOC(=O)c1[nH]c(C)c(C(=O)N2CCN(CC)CC2)c1C +Cc1cc(C)c2nc(NC(=O)c3c(C)c(C)nn(C)c3=O)sc2c1 +COc1ccc(CC(=O)NCC2(O)CCOCC2)cc1OC +CC(C)(C)CC(=O)Nc1cccc(-c2cn[nH]c2)c1 +CCNC(=O)c1ccc(CNC(=O)c2c[nH]c3ccccc3c2=O)cc1 +Cc1ccc(C(=O)CN2CC(C)OC(C)C2)cc1C +O=C(NCc1cc(-c2ccco2)on1)c1cnn2c1CCCC2 +CC1CCCC(N(C)C(=O)Cc2cccc(OCC#N)c2)C1 +O=C(Cc1ccc(F)cc1)N1CCC(Nc2ncnc3c2CCC3)C1 +COc1ccnc(NC(=O)CCCc2nc3ccccc3c(=O)[nH]2)c1 +Cc1nn(C)c(Oc2ccccc2)c1CNCCc1nccs1 +O=C(COc1cccc(F)c1)NCC1COc2ccccc2O1 +CC1CCc2c(C(=O)NC(C)c3nnc4ccccn34)csc2C1 +O=C(NCc1nccc(N2CCCCC2)n1)c1cccs1 +Cc1cnc(NC(=O)N(C)CCOc2cccc(Cl)c2)s1 +CCCNC(=O)CNc1cc(OC)c(Cl)cc1OC +C=CCNC(=O)COCc1cc(-c2ccc(F)cc2)on1 +O=c1c2cnc3ncnn3c2ccn1-c1ccc(Cl)cc1Cl +Cc1c(C(=O)NCCc2ccccn2)oc2c1C(=O)CC(C)(C)C2 +O=C(N1CC(CO)C(CN2CCOCC2)C1)C1(c2ccccc2)CC1 +CN(C)c1cccc(C(=O)N2CCC(c3ccccc3)C2)c1 +CCN(CC)C(=O)c1cc(-c2cncnc2)nc2c(C)c(C)ccc12 +CN(C)c1ccc2nc(C(=O)Nc3ccccc3)sc2c1 +COc1ccc(C(=O)N2CCCn3cncc3C2)c(OC)c1OC +O=C(COC(=O)c1cnccn1)c1ccc2ccccc2c1 +Nc1cccc(S(=O)(=O)Nc2nccnn2)c1 +Cc1cc(C)c(CNC(=O)NC(C)c2nc(C)no2)c(C)c1 +COCCOc1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1 +Cn1nc(C(=O)Nc2ncc(C(N)=O)s2)c2ccccc2c1=O +Nc1nc(N2CCOCC2)ncc1C(=O)Nc1ccncc1 +Cc1cnn(CC2CCCN2C(=O)c2cnc3onc(C)c3c2)c1 +Cc1cccc(C)c1NCc1cc(F)c(F)cc1F +Cc1noc(C)c1C(C)NS(=O)(=O)CCCCC#N +CCCCc1n[nH]c2c1CN(C(=O)c1ccc(OCC)o1)CC2 +CNC(=O)c1ccc(NC(=O)C2(c3ccc(Cl)cc3)CCC2)cc1 +O=C(c1cc(-c2ccco2)[nH]n1)N1CCCC1c1ccsc1 +CC(NC(=O)OC(C)(C)C)C(=O)NCc1nncn1C +Cc1cc(C(=O)NC2CCc3cc(F)ccc32)c2c(C)noc2n1 +CN(Cc1ccccn1)C(=O)c1cccc(OCC(F)F)n1 +COc1ccc(Cc2cn3c(C)c(C#N)ccc3n2)cc1 +Cn1c(C(=O)Nc2cccc(C#N)c2)nc2ccc(O)cc21 +CC(C)CN(CC(C)C)C(=O)c1cc(S(C)(=O)=O)ccc1Cl +Cc1cc(C)c(C(=O)NCCc2ccccn2)c(C)c1 +Cc1ccc[nH]c1=NS(=O)(=O)c1ccc(C#N)c(Cl)c1 +CN(Cc1cc(Cl)cc(Cl)c1)Cc1c[nH]nc1-c1cccnc1 +Cn1cc(Cl)cc1CNC(=O)NC1C2CCOC2C12CCCC2 +CCc1noc(CC)c1CC(=O)N(CC)Cc1c(F)cccc1F +Cc1nc(-c2cccc(NCc3ccoc3)c2)n[nH]1 +Cc1onc(-c2ccccc2)c1C(=O)NCc1nc2ccccc2n1C +Cc1nc(C2CCCN(C(=O)c3sccc3C)C2)no1 +CCC(C)OCCCC(=O)Nc1ccc(Cl)c(N)c1 +Cc1n[nH]c(C)c1N1CCN(Cc2ccc(F)c(F)c2)CC1 +CCn1nc(C)c(C(=O)Nc2sc3c(c2C(N)=O)CCC3)c1C +COc1ccc(NC(=O)Cc2sc(C)nc2C)cc1Cl +Cc1cccnc1CNC(=O)Nc1ccc(N2CCCC2=O)cc1 +Cc1cnn(-c2ccc(C(=O)NCc3cnc(C)s3)cc2)c1 +CCn1ccc(=O)n(Cc2nc(-c3ccsc3)no2)c1=O +CC(=O)N1CCCc2cc(S(=O)(=O)N=c3ccc(C)c[nH]3)ccc21 +CC(COc1ccccc1)c1nc(-c2ccc(C#N)cn2)no1 +COc1ccc(COCC(=O)Nc2cccc(C#N)c2)cc1 +Nc1ccccc1CC(=O)Nc1cc(F)cc(F)c1 +CCC(C)(O)CNC(=O)Nc1ccc(F)c(C(N)=O)c1 +CCCCS(=O)(=O)N1CCCC1C(=O)Nc1ccc(C)cc1 +COC(=O)COC(=O)c1ccc(-c2cccs2)o1 +CC(NC(=O)CCC(C)(C)C)C(=O)Nc1ccccc1 +COc1ccc(Cl)cc1NS(=O)(=O)c1ccccc1N +Cc1nc(-c2cccc(Br)c2)oc1C +COc1cccc(C(=O)NC(C)c2ccc(-n3cncn3)cc2)c1 +COCCNC(=O)C1CN(C(=O)c2ccc3c(c2)OCO3)C1 +Cc1nn2c(nnc3c(=O)n(-n4cnnc4)ccc32)c1-c1ccccc1 +COCC(=O)NCC1CCN(C(=O)c2cnccn2)CC1 +CC(CC(=O)c1ccco1)NC(=O)C1CC(=O)N(Cc2ccco2)C1 +CCOc1ncc(NC(=O)c2ccncc2)c(OCC)n1 +Cn1ccnc1Cn1ccnc1-c1cccc(Br)c1 +COc1ccccc1Nc1ncnc(-n2cccc2)n1 +O=C(CSc1ccncc1)NCc1ccnc(OC2CCCC2)c1 +CCOc1ccc(CC(=O)N(Cc2ccsc2)C2CC2)cc1 +CCn1nc(C)cc1NS(=O)(=O)c1cnn(C(C)C)c1 +COC(=O)c1ccc2c(c1)nc(C(C)=O)n2C1CC1 +CCCCNC(=O)Cn1c(=O)ccn(Cc2ccccc2Cl)c1=O +NC(=O)N1CCC2C(COC2CNC(=O)c2ccsc2)C1 +CC(NC(=O)c1ccc(Br)c(F)c1)C(=O)N1CCCC1 +CCOc1ccc(C(=O)Nc2c(C)nc3c(C)cccn3c2=O)cc1 +Cc1ccc(-c2nc(C)c(C(=O)NCCc3ccc(O)cc3)s2)o1 +COc1cccc(NC(=O)NCc2ccc3c(c2)CCN3C(C)=O)c1 +O=C(OCC(=O)c1ccccc1Br)c1ccccn1 +Cc1cc(C)nc(NC(=O)Nc2ccc3c(c2)CCC3)c1 +O=C(NCC(F)(F)F)C1CCN(C(=O)C2CCCC2)CC1 +C#Cc1cccc(NC(=O)CNC(=O)CC(F)(F)F)c1 +CCOC(=O)COc1nc(CC(C)C)c2c(c1C#N)CCC2 +CCC(C)n1nccc1NC(=O)c1cccc(SCC#N)c1 +CCOc1ccc(F)c(C(=O)Nc2nn(C(C)(C)C)cc2C#N)c1F +COc1ccc(F)cc1C(=O)CNc1ccccc1F +Cc1cnc(C2NCCc3cc(C(F)(F)F)ccc32)cn1 +COC(=O)c1cccc(C(=O)NCCOC2CCCCC2C)n1 +Nc1nccnc1C(=O)NCc1ccc2c(c1)OCCO2 +Cc1ccc(S(N)(=O)=O)cc1NC(=O)CSc1ncn[nH]1 +CNC(=O)CNS(=O)(=O)c1cc(Cl)cc(Cl)c1 +COc1cccc(S(=O)(=O)Cc2noc(C)n2)c1 +Cc1cc(C(=O)Cn2cnc(C#N)n2)c(C)n1-c1nccs1 +CC(C)C12CN3CC(C(C)C)(CN(C1)C3C(C)(C)CO)C2=O +Cc1cc(C)n2nc(SCC(=O)c3ccccc3)nc2n1 +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1coc(-c2ccccc2)n1 +COC(=O)CNC(=O)CNC(=O)Nc1ccc(Br)cc1 +CC(C)(NC(=O)CC1OC(=O)c2ccccc21)c1cccc(F)c1 +Cc1cnc(C(=O)N2CCC(OCc3ccccc3C)CC2)cn1 +Cc1cc(C(=O)Nc2ccnn2Cc2cnn(-c3ccccc3)c2)[nH]n1 +CCc1nc(COc2ccc(OC)cc2)sc1C +COc1ccc(NC(=O)Cc2cccc(F)c2)c(OC)c1 +Cc1cc(F)ccc1S(=O)(=O)N1CCC(=O)CC1 +O=C(NCCCc1nnc2ccccn12)c1ccccc1 +CCc1nnsc1C(=O)NCc1cccc(NC(=O)C(C)CC)c1 +O=C(Nc1cnn(-c2ccccc2F)c1)c1c(F)cccc1F +CCCCNC(=O)c1onc(-c2cccnc2)c1N +CC1CCN(C(=O)c2ccccc2NC(=O)N(C)CC2CC2)CC1 +Cc1ccc(CCC(=O)N2CCC3C(CCC(=O)N3C3CC3)C2)o1 +Cc1cccc2c1CCN2C(=O)c1c[nH]c2c(cnn2C)c1=O +Cc1cc(Nc2ccc(S(N)(=O)=O)cc2)nc(C)n1 +Cc1cc(=O)n(C)cc1NC(=O)N(C)CCOc1ccc(F)cc1 +CCc1ccc(C(=O)N2CCN(c3ncccn3)CC2)cc1 +CCCOc1cc(CO)cc2c1OC(CC)(CC)C(=O)N2 +Cc1nc(NC(=O)C23CCC(C)(C(O)C2)C3(C)C)sc1C +CN(CCOCC1CC1)C(=O)c1ccc(N2CCCCC2=O)cc1 +O=S(=O)(NCc1nnc2n1CCCCC2)c1ccc(F)cc1F +CCCC1CN(C(=O)Nc2ccc(C)cc2OC)CCO1 +Cc1nc2cc(N(CC3CC3)C(C)C)c(N)cc2s1 +COc1cccc(NC(=O)N2CCOCC2C2CC2)c1 +FC(F)(F)c1nc(N2CCCC2Cn2cncn2)c2ccccc2n1 +CCC1(C)CC(NC(C)=O)c2cc(C(C)O)c(C)c(C)c2O1 +COC(=O)C1CN(Cc2cnc(C3CC3)s2)CCO1 +O=C(NCC1CCN(c2cnccn2)CC1)Nc1c(F)cccc1F +COc1cc(CNc2nc(C3CC3)no2)cc(OC)c1OC +COC(=O)c1ccc(C(=O)Nc2ccc(Br)cc2C)cn1 +O=C(NCc1nc2ccccc2[nH]1)c1cccnc1 +COc1ccc2c(CC(=O)NC(C)(C)C)cc(=O)oc2c1 +Cc1noc(COCC(=O)Nc2cnn(CC3CCCO3)c2)n1 +CCOC(=O)c1sc(NC(=O)c2sc(C)nc2C)cc1C +Cc1csc(NC(=O)NCc2c(C)nn(-c3ccccc3)c2C)n1 +O=C(NCC1Cc2ccccc2O1)c1ccc(OCC(F)F)nc1 +O=C(NCCNC(=O)c1ccc2[nH]ccc2n1)c1ccc(F)cc1 +C#CCOc1ccc(C(=O)N2CCOCC2C2CC2)cc1 +O=C(c1cccnc1)N1CC2OCC(=O)N(Cc3ccccn3)C2C1 +COCCNS(=O)(=O)c1ccc(S(N)(=O)=O)cc1F +Cc1cc(SCC(=O)Nc2cc(Cl)ccc2O)n2cnnc2n1 +O=C(NCC1CC1)c1nc2c(o1)CN(C(=O)c1cccnc1)C2 +CCC1CCCN(C(=O)c2ccc(OCC(N)=O)cc2)C1 +O=C(NC1CC2CC1N(C(=O)Cc1cccnc1)C2)c1cccs1 +CC(C)CCn1cnc2c(oc3ccccc32)c1=O +C1=C(c2c[nH]c3ccccc23)CCN(Cc2cnc3cnccn23)C1 +CN(Cc1nncn1C)C(c1ccccc1)c1ccc(F)cc1 +CC(C)(C)OC(=O)N1CCc2ccc(-c3cncnc3)cc21 +COc1cc(C(=O)N2CCCC2c2ccncc2)cc2c1OCCO2 +CC(C)Cc1cc(C(=O)NCCc2nc3ccccc3s2)[nH]n1 +CC(=O)NC(Nc1cccc(C)c1)(C(F)(F)F)C(F)(F)F +COc1cccc(C(C#N)NCc2ccccn2)c1OC +COc1cccc(S(=O)(=O)C(C)C(=O)Nc2ccc(C)cc2C)c1 +C#CCNc1cc(C(F)(F)F)ccc1OCCOC +COc1ccc(OCC(=O)Nc2cccc(C)c2)c(N)c1 +COCCN(CC(N)=O)C(=O)c1ccc(C)cc1Br +CCc1ccc(C(COC)NC(=O)Cc2ccc(F)cc2F)o1 +CC(C)C(NC(=O)NCC1CN2CCCCC2CO1)c1ccccc1 +O=C(NC(CO)c1ccccc1)c1ccc(F)cc1 +CCc1ccc(OCc2nc(C)c(CCO)s2)cc1 +CCc1ccc(-c2c(-c3ccccc3)ncn2CCCn2cncn2)o1 +CC(C)OC(=O)CNC(=O)c1cn(C)nc1C(C)(C)C +COc1ccc(C(=O)CCC(=O)N2CCNCC2)cc1F +CCCCN(C)C(=O)Cn1nnc(C(N)=O)c1C +Cc1ccc(C)n1-c1sccc1C(=O)NCCc1ccccn1 +CCc1c(C)nc2n(c1=O)CC(C(=O)NCCOC)CS2 +CC(O)c1cccc(NC(=O)NCCC(F)(F)F)c1 +CNC(=O)CSc1nc(O)c2cnn(-c3ccccc3C)c2n1 +COCCN1CC(c2nc3ccccc3n2CC(=O)OC)CC1=O +CCNS(=O)(=O)c1ccc(OC)c(C(=O)NC)c1 +CC(C)n1cnnc1S(=O)(=O)C(C)C(=O)N1CCc2ccccc21 +O=C(N1CCc2cnccc21)C1(c2cccc(Cl)c2)CC1 +CCc1ccc(C(=O)NCCOC2CCCCC2C)o1 +O=C(NCc1cccnc1-n1ccnc1)N1CCc2ccccc21 +O=C(NCCc1nc(-c2ccc(F)cc2)no1)c1ccccc1 +CCCC(C)N1CC(C(=O)NCc2cn3ccccc3n2)CC1=O +CCc1noc(CC)c1CC(=O)N(C)Cc1ccc(C(=O)NC)cc1 +O=C(CN1CCCCC1=O)NCCCC1CCCCC1 +Cc1csc(CNc2ccccc2Br)n1 +O=C(NC1CC(=O)N(c2ccccc2)C1)C1CCCC1 +Cc1cc2occ(CC(=O)N3CCC(C(N)=O)C3)c2cc1C(C)C +Cc1ccc(OCCNC(=O)NCc2cccc(N(C)C)c2)cc1 +CC(C)Oc1ccc(-c2nc3n(n2)C(=O)CS3)cc1 +O=C(CO)NC1CC(=O)N(CCc2ccc(F)cc2)C1 +CCOc1ccc(C(=O)NCC(=O)Nc2cc(F)cc(F)c2)cc1 +Cc1ncoc1C(=O)NC1CC(=O)N(Cc2cccc3ccccc23)C1 +Cc1cc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)c(F)cc1F +COC(=O)C1=C(C)N(C)C(=O)N(C)C1c1ccc(F)cc1 +COc1cccc(OCCN2CCCS2(=O)=O)c1OC +CC(C)CCn1nc(-c2cccc(F)c2)cc(CC#N)c1=O +Cc1ccc(Oc2ccccc2CNC(=O)CNS(C)(=O)=O)cc1 +CN(CCc1ccccn1)c1ccc(Cl)cc1N +COc1cccc(C(=O)NC2CCCC2C)c1F +O=C(c1cc[nH]n1)N1CCCC(c2[nH]ncc2-c2ccccc2)C1 +CCOc1ccc(F)c(C(=O)NCCc2ccc3c(c2)OCO3)c1F +CCOc1ccc(C(=O)Nc2cc(Cl)ccc2C#N)nn1 +Cn1cc(CN2CCN(C(=O)Nc3ccccc3)CC2)c2ccccc21 +Cc1ccc(C)c(S(=O)(=O)N2CCCn3nccc32)c1 +CCC1c2ccsc2CCN1C(=O)c1cc(C2CC2)[nH]n1 +CCCNC(=O)NCc1c(C)nn(CCOC)c1C +O=C1NCC(C(=O)NCCc2ccc(F)c(Br)c2)N1 +COCCN1CCN(C(=O)c2ccc(O)c(Cl)c2)CC1=O +CC(=O)c1cccc(NC(=O)C(C)Sc2nncs2)c1 +O=C(Nc1cc(C(F)(F)F)ccc1O)c1ccc2c(c1)OCO2 +COc1nn(C)cc1C(=O)NCC(O)c1cccs1 +COC(=O)N1CCCN(C(=O)Nc2ccc(F)cc2OC)CC1 +NC(=O)CCN(C(=O)c1ccnc(-n2cncn2)c1)c1ccccc1 +CCCCNC(=O)CN(C)S(=O)(=O)c1cccs1 +COC(=O)c1ccc(NCC(=O)N2CCCCC2)cc1 +O=C(c1cc2sccc2[nH]1)N1CCOC(C(F)(F)F)C1 +COc1cccc(OCCCc2nc(CO)cs2)c1 +Cc1ccc(C(O)CNC(=O)c2ccncc2)cc1 +NC(=O)Cc1nc(-c2c[nH]c(=O)c(Cl)c2)n(-c2cccc(F)c2)n1 +CCNC(=O)CCS(=O)(=O)c1ccc(C(F)(F)F)cn1 +Cn1c(=O)c(C(=O)NCc2ccc(F)cc2)nc2ccccc21 +Cc1cc(C)c(NC(=O)C2CCCN2C(=O)OC(C)(C)C)c(C)c1 +CC1CCCN(C(=O)CCCOc2ccc(S(C)(=O)=O)cc2)C1 +O=C(Cn1ccc(=O)[nH]c1=O)NCC12CC3CC(CC(C3)C1)C2 +Cc1cccnc1NC(=O)c1cc(Cl)ccc1F +Cc1nc(C)c(C(=O)Nc2cnn(CC(=O)N(C)C)c2)s1 +CN(C(=O)COC(=O)c1ccc(O)cc1O)C1(C#N)CCCCC1 +CC(NC(=O)CNc1ccc(N2CCCC2=O)cc1)c1ccco1 +COc1cc(Cl)c(C)cc1NC(=O)CNc1ccc(C(N)=O)cc1 +C=C(C)Cn1c(=O)c2c(nc3oc(C)c(C)n32)n(C)c1=O +O=C(NCCn1ccc2ccc(Cl)cc21)c1ccncc1 +Cn1cnc2c1c(=O)n(CCCN1CCOC(C)(C)C1)c(=O)n2C +COc1ccccc1NC(=O)C1CN(C(=O)c2c[nH]c3ccccc23)C1 +CCn1nc(C)cc1C(=O)NCC(=O)N(C)Cc1ccc(Cl)cc1 +COc1ncccc1C(=O)N1CCN(Cc2ccc(Cl)cc2)CC1 +O=C(Nc1nc(-c2ccc(F)c(F)c2)cs1)c1ccc(F)nc1 +CCn1cc2c3c(cccc31)CN(C(=O)c1ccc(OC)cc1)CC2 +FC(F)(F)CCc1ccccc1NCc1nnnn1C1CC1 +COCC(=O)N(C)CC(=O)NCC1C2CCc3ccccc3C21 +NC(=O)C1CCN(C(=O)c2noc3c2CCCCC3)CC1 +Cc1[nH]ccc1C(=O)N1CCCC2(CCC(=O)N(CCC(C)C)C2)C1 +COC(=O)C1CCN(C(=O)CS(=O)(=O)c2ccc(C)cc2)CC1 +Cc1cc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)nn1C(C)C +CCC(NC(=O)Nc1cnn(-c2ccccc2F)c1)c1noc(C)n1 +CC(C)n1cc(-c2nc(-c3ccncc3)no2)cn1 +Cc1csc(=O)n1CC(=O)N(Cc1ccccc1)Cc1ccco1 +O=C(NCCC(O)c1ccc2c(c1)OCO2)NCc1cccs1 +COCC(=O)Nc1ccc(OC)c(OC(F)F)c1 +Cc1cc(C(=O)N2CCCC(C)CC2)c2c(C)nn(C)c2n1 +Cc1csc(NC(=O)c2cnc3sc(C)cn3c2=O)n1 +CCCCN(CC)C(=O)NCc1ccc(S(N)(=O)=O)cc1 +Cc1nc(C)c(C(=O)N2CCCC(c3ccn[nH]3)C2)s1 +Cc1cc(Cl)ccc1NC(=O)c1ccc(=O)n(C)c1 +COc1ccccc1C(C)N(C)Cc1cc(C(N)=O)cs1 +CCN1CC(C(=O)Nc2ccc3c(c2)OC2(CCCCC2)O3)CC1=O +Cc1noc(C)c1S(=O)(=O)NCC(O)c1cn(C)c2ccccc12 +Cc1occc1C(=O)N1CCN(C(=O)c2cccc3[nH]ncc23)CC1 +Cc1c(C(=O)OC2CCCCC2)sc2[nH]c(=O)[nH]c(=O)c12 +COCCCCCNC(=O)c1cc2ccccc2oc1=O +CN(CC(=O)Nc1cc(Cl)ccc1O)S(C)(=O)=O +Nc1cccc(CNS(=O)(=O)c2ccccn2)c1 +CC(C)C(Oc1ccccc1C#N)C(=O)Nc1ccc(F)c(C#N)c1 +Cc1csc(C(C#N)C(=O)c2ccc(-c3cscn3)cc2)n1 +Cc1cc(C)c(NCC(=O)Nc2cc(C)nn2C)c(C)c1 +O=C(NCc1ccncc1)NCc1cccc(Cl)c1 +[H]N=c1n(C)c2ccccc2n1CC(=O)c1ccc(Cl)cc1 +Nc1ccc(=O)n(CCCOc2ccc(F)cc2)c1 +O=C(Nc1ccccc1C(=O)Nc1nccs1)c1ccc(F)cc1 +CCC(=O)Nc1cccc(NC(=O)CSc2ccc(OC)cc2)c1 +COCC(=O)NC(C)c1cc(OC)c(OC)c(OC)c1 +O=C(NCCCO)Nc1ccc(C(=O)NC2CCCCC2)cc1 +O=C(c1c[nH]c2ccc(F)cc2c1=O)N1CCN2CCCCC2C1 +CCCNC(=O)c1cc(S(=O)(=O)N(C)c2ccccc2)cs1 +O=c1[nH]c2ccccc2nc1C=Cc1cccc(O)c1 +COCc1nnc(NC(=O)CC(C)n2nnc3ccccc32)s1 +CC(=O)N1CCc2c(nc(N(C)C)nc2NCCC2CCCCO2)C1 +C=C(C)CN(CC)C(=O)C(C)Sc1nnc(C2CC2)n1C +COc1cccc(C(=O)N2CCCC(C)C2C)c1O +Cc1cc(C)cc(CCNC(=O)c2[nH]ncc2Br)c1 +COc1ccc(C(=O)NCc2nc3ccc(F)cc3[nH]2)cc1 +c1ccc(CNc2cc(-c3ncnc4c3CCC4)c3cc[nH]c3n2)nc1 +C=CCN(Cc1ccc(OC)cc1)C(=O)Cc1ccc[nH]1 +Cc1n[nH]c(C)c1CCn1cc(-c2cccc(C#N)c2)nn1 +CC(C)Cn1cnnc1C1CCCN1C(=O)CSc1ccccc1 +O=C(NC1CCN(C(=O)C2CC2)CC1)c1cc(Cl)ccn1 +NC(=O)C1CCN(C(=O)c2ccc(O)c(Cl)c2)CC1 +Cc1cc(C)cc(C(=O)NCC(=O)Nc2cccc3cccnc23)c1 +CC1Nc2cc(Cl)c(Cl)cc2N(CC(N)=O)C1=O +COCC(=O)Nc1ccc(NCc2ccc(F)cc2Cl)cc1 +CCOCC(O)CN1CCN(C(=O)c2c(C)nn(CC)c2C)CC1 +COc1ccc(C(C)NC(=O)Nc2nncs2)cc1F +Cc1ccc(-n2nnnc2N2CCc3ccccc3C2)cc1 +COCc1ccccc1CNC(=O)c1cc2ccccc2[nH]1 +CS(=O)(=O)NCCCSc1cccc(Br)c1 +Cc1cccc(-n2nc(N3CCOCC3)cc2N)c1C +Cc1nc[nH]c1C(=O)NCCNC(=O)c1ccccc1Cl +Cn1cc(C(=O)Nc2ccc(OC3CCOC3)cc2)c(C(C)(C)C)n1 +Cc1cc(C)c2oc(=O)cc(CNC(=O)Cc3cccs3)c2c1 +CCc1cccc(C)c1NCC(=O)c1ccc(F)cc1 +Cc1csc(=O)n1CC(=O)NC(C)COc1ccc(F)cc1F +O=C(c1cc(Cl)ccc1O)N(CC(F)(F)F)C1CC1 +COc1cccc(C(=O)CN2CCOc3cccc(N)c32)c1 +COc1cc(-c2ccc(OCc3ccccc3)nc2)ncn1 +CC(NC(=O)c1cn(C)nc1C(C)(C)C)c1ccc2c(c1)CC(=O)N2 +CCCCC(NC(N)=O)C(=O)Nc1cc(C)ccc1C +CCNC(=O)CN1CCN(C(C)C(=O)N(C)CCC#N)CC1 +Cc1ccc(CNC(=O)CCn2cc(C)cn2)c(C)c1 +Cc1cc(C)n(-c2ccc(C(=O)N(C)Cc3c(C)noc3C)cc2)n1 +CC(C)CN(CCO)S(=O)(=O)c1ccc(Cl)cc1 +c1csc(Cn2nnnc2Sc2nc3ccccc3o2)c1 +Cc1nnc(NC(=O)CSc2nnc(-c3cccnc3)n2C)s1 +CC(C)(O)CSc1nnc(NC2CCCCC2)s1 +Cc1csc(C2CN(Cc3ccccc3OCC3CC3)CCO2)n1 +N#Cc1c(-c2ccccc2)cc2cnn(-c3ccccc3)c(=O)c2c1N +Cc1nnc(Nc2cc(Cl)ccc2Cl)[nH]c1=O +COc1cc(CNS(=O)(=O)c2cc(F)ccc2C)ccn1 +O=C(NCC(Cc1cccc(F)c1)N1CCNC1=O)c1cccnc1 +CN(C)C(=O)CNC(=O)C1(c2ccccc2)CCC1 +COC(=O)c1c(N)n(Cc2ccco2)c2nc3ccccc3nc12 +CN(CCNC(=O)Nc1nccs1)c1ccccc1 +CNC(=O)c1nc(OC(C)(C)C)ccc1OC1CC1 +CCc1[nH]nc(C(=O)NC2(C)CCCCC2)c1N +Cc1ccccc1NC(=O)NCc1cc(-c2ccncc2)n(C)n1 +O=C(CSc1ncn[nH]1)Nc1ccc(Br)cc1F +CCc1nc2n(n1)CCCC2NC(=O)C1Oc2ccccc2C1C +Cc1ccc(NC(=O)c2ccc3nccnc3c2)cc1S(C)(=O)=O +Cc1ccc2c(c1)N(C(=O)CCSc1ccccn1)CC2 +CCOC(=O)N1CCN(C(=O)CN(C)S(C)(=O)=O)CC1 +Cc1nc(C(=O)N2CCCC2Cn2cnc3ccccc32)c[nH]1 +Cc1cccc(C(=O)OCC(=O)N2CCOCC2)c1 +O=C(Nc1cccc(OCc2cccnc2)c1)c1ccc2c(c1)OCO2 +Cn1c(CN2CCOC(c3nccs3)C2)nc2cc(Cl)ccc21 +CCn1cnnc1CNC(=O)c1ccc(C(C)=O)s1 +CCC(=O)N(CC1CCCO1)c1nc2c(OC)cccc2s1 +Cc1noc(C)c1CCC(=O)NCC#Cc1ccc(C(N)=O)cc1 +CC(=O)Nc1ccc(SCc2nccn2C(F)F)cc1 +CSc1ccsc1C(=O)N1CCc2cc(F)ccc2C1 +CCOCc1cccc(NC(=O)N(C)C(C)c2cccc(O)c2)c1 +COCCCNC(=O)Cc1csc2nc(-c3ccc(F)cc3)cn12 +O=S(=O)(N1CCOCC1)N1CCc2cc(F)ccc2C1 +Cc1noc(C)c1C(C)NC(=O)c1n[nH]c2ccccc12 +CCCOc1ccc(-c2csc3nc(N)cn23)cc1 +CC(NC(=O)CCOc1ccccc1Cl)c1nnc2n1CCC2 +Cc1ccc(Cl)cc1NC(=O)N(C)C(C)CC#N +Cc1nc(CNC(=O)Nc2ccccc2OCC(F)F)no1 +CC(NC(=O)NC1CCN(C(=O)C2CC2)CC1)c1ccccc1 +Nc1cc(-c2cccs2)nn(CC(=O)c2ccccc2)c1=O +CCCN(CCC)C(=O)c1snc(C#N)c1N +Cn1c(N2CCC(C(=O)NC3CCCC3)CC2)nc2ccccc21 +Cc1nc(C2CC2)nc2sc(C(=O)OC(C)C(N)=O)c(C)c12 +Cc1nc2cc(-c3ccco3)nn2c(N2CC(C)OC(C)C2)c1C +O=C(NCCn1ccc2ccccc21)c1[nH]nc2c1CCC2 +O=C(Nc1nnc(-c2ccccc2)s1)c1cccs1 +Cn1cc(CN2CCOC(C#N)C2)c(-c2cccnc2)n1 +COc1cc(C)c(NS(=O)(=O)c2cccc(C#N)c2)cc1OC +CCC(C(=O)N1CCCC1)N(c1cccc(OC)c1)S(C)(=O)=O +Cc1c(C(=O)NCc2cc(C(C)C)no2)cnn1C +O=C(CN1C(=O)COc2ccc(Cl)cc21)NCc1ccc(F)cc1 +O=C(CN1CCN(c2cccc(Cl)c2)C1=O)NCCn1cccc1 +CCC(CC#N)N1CCN(c2cccc(Cl)c2)CC1 +COc1ccccc1CNC(=O)Cc1c(C)[nH]c(=O)[nH]c1=O +CCC(C)OCCC(=O)Nc1c(Cl)cc(N)cc1Cl +CC(C)NC(=O)CCNC(=O)NC(C)C1CCCO1 +CC(CNC(=O)Cc1csc(-c2nc[nH]n2)n1)Oc1ccccc1 +CCNC(=O)NC1(C(=O)NC(C)COC)CCCC1 +O=C(c1cc[nH]n1)N1CCCN(C(=O)c2ccccc2F)CC1 +CNC(=O)NCC(=O)NCc1cn2cc(Br)ccc2n1 +Brc1cnc2oc(N3CCCCCC3)nc2c1 +COC(=O)Cc1cc(OC)c(OC)cc1S(N)(=O)=O +COC(=O)c1cc(OC)c2c(c1Br)OCO2 +COc1ccccc1OCCC(=O)Nc1cc(C)ccn1 +O=C(c1ccc[nH]1)N1CCC2(CCC(=O)N2CC2CC2)CC1 +CCc1cc(C(O)c2ccco2)cc2c1NC(=O)C2(C)C +CCc1cccc(OC(=O)CNC(=O)Cc2cccc(F)c2)c1 +Cc1nccn1-c1ccc(NC(=O)c2cn(C)nn2)cn1 +O=C(COC(=O)c1c(Cl)cccc1Cl)NCC1CCCO1 +Fc1ccc(CNc2ncnc3c2cnn3-c2ccc(F)cc2)cc1 +O=C(Nc1nc2c(s1)CCC2)C1(n2cnnn2)CCCCC1 +CCCC(C)NC(=O)CN1CCc2cc(S(N)(=O)=O)ccc21 +COc1ccc(OC)c(C2CCN(C(=O)c3cccc(CO)n3)C2)c1 +CC(=O)N1CC(=O)c2c1ccc(Br)c2Cl +Cc1ccc(C(=O)N2CCN(Cc3nc(CC(C)C)no3)CC2)o1 +O=C(c1ccccc1N1CCCC1)N1CCC2(CC1)OCCCC2O +CC(=O)NCc1ccc(S(=O)(=O)Oc2ccc(C)cc2C)s1 +CSc1nnc(C(=O)NCC(F)(F)F)n1C +Cc1cc(C)n(CCC(=O)Nc2nc3ccccc3[nH]2)n1 +CC(Sc1ccccc1F)C(=O)NC1CCCC1 +COc1ccc(OC)c(C2CCCN2C(=O)c2cc(C3CC3)[nH]n2)c1 +COc1ccc(C(=O)Nc2ccccc2SC(=O)N(C)C)c(F)c1 +COc1ccc(C)cc1-n1nc(CO)cc1C(C)C +CCc1cc(N)cc(C)c1NC(=O)c1ccc(Cl)cc1Cl +COCCOc1ncccc1C(=O)N(C(C)C)C1CCOCC1 +CC(C)CNC(=O)C1c2ccccc2CC(=O)N1Cc1ccccc1 +Cc1nnc(CN2CCN(C(C(N)=O)c3ccc(Cl)cc3)CC2)o1 +CCC(CO)N(Cc1cccs1)C(=O)c1ccoc1 +CCC(CC)N(CCO)C(=O)c1cc(N)ccc1F +CC(C)c1cc(NCc2ccncc2)n2nccc2n1 +CCS(=O)(=O)NCC(=O)NCc1ccccc1 +O=S1(=O)CCCN1Cc1cc(F)cc2cccnc12 +CCCN(C)C(=O)c1ccn(-c2cccc(N)c2)n1 +CC1c2ccsc2CCN1C(=O)c1ccc2c(c1)OCO2 +NC(=O)CCN(C(=O)Cc1ccc(F)cc1)c1ccccc1 +Cc1ccc(NCCN2CCNC2=O)c(Br)c1 +CC1Oc2ccccc2N(CC(=O)NCC2CCOC2)C1=O +Cc1ccc2ncc(C(=O)N3CCC(OCC4CCCO4)CC3)n2c1 +Cc1cc(C)cc(OC(=O)Cn2ccc(=O)n(C)c2=O)c1 +CC(C)C(=O)NCc1ccc(N2CCCCC2=O)cc1 +O=C(CCCNC(=O)c1ccsc1)NCc1ccccn1 +Cc1cc(NC(=O)CCN2C(=O)CSc3ccccc32)n(C)n1 +O=C(Cc1ccc(Br)cc1)Nn1cnnc1 +COc1c(C2NCCNC2=O)cc(C)cc1C(C)(C)C +COC(=O)c1ccc(NC(=O)c2ccc(C)c(NC(C)=O)c2)cc1 +CNC(=O)CNC(=O)c1ccccc1-c1ccccc1C#N +CC(C)N(C)c1cccc(NC(=O)CCCN2CCOC2=O)c1 +Cc1ccc(NC(=O)CSc2nnc(-c3ccncc3)o2)cc1 +COC(=O)C(C)n1nc(CO)cc1-c1cc(C)ccc1C +COc1c(NC(=O)NCCCc2cnn(C)c2)c(C)nn1C +CC(=O)Nc1ccc(OCc2ccc(-n3cccn3)cc2)cc1 +CC(C)CC1CCCCCN1C(=O)NCC(=O)N1CCCC1 +O=c1cc(C2CCC2)ncn1Cc1csc(C2CC2)n1 +COc1cccc(OCC(=O)Nc2nc3c(s2)COCC3)c1 +Cc1cc(C(=O)Nc2c(C)nn(C(C)C)c2C)c2ccc(F)cc2n1 +Cc1nnc(NCCNC(=O)OC(C)(C)C)c(C#N)c1C +O=c1[nH]nc(CSc2cc3c(cc2Cl)OCCO3)[nH]1 +O=C(Nc1ccccc1Br)c1cscn1 +O=C1CCC(NC(=O)Nc2cccc3ccccc23)CN1 +CC(NCc1cnc(C2CCC2)s1)c1noc(-c2ccccc2)n1 +CC1(C)Cc2c(nn(-c3ccccc3)c(=O)c2C#N)CO1 +CCC(C)NC(=O)N1CCN(C(=O)c2ccc(OC)cc2)CC1 +CCCOc1ccc(C(=O)Nc2cccc(C(=O)NCC)c2)cc1 +Nc1ccc(S(=O)(=O)NCCCCn2ccccc2=O)cc1 +N#Cc1ccc(-c2cc(C(=O)c3ccccn3)c(N)o2)cc1 +CCNc1cncc(S(=O)(=O)N2CCCC2)c1 +COC(=O)C(C)NC(=O)C12CC3CC(CC(Br)(C3)C1)C2 +O=c1[nH]c2cc3c(cc2cc1CNc1ccc(Cl)cc1)OCO3 +O=C(NCc1ccccc1OC(F)F)c1cc(-c2ccccc2)[nH]n1 +O=C(NC1CCOC(C2CC2)C1)NC1CCN(CC(F)(F)F)C1 +O=C(NCC1CCOC1)c1coc(COc2ccc3c(c2)OCO3)n1 +O=C(NCCOCC1CC1)C1CCN(c2cnccn2)CC1 +Cc1ccc(N(CCC#N)C(=O)CN(C)c2ccccc2)cc1C +O=C(Cn1c(Cc2ccccc2)nc2ccccc21)NCC1CCCO1 +Cc1ccc(C(=O)OCC(=O)Nc2cccc(Cl)c2C)cn1 +OC1=Nc2c(ncn2-c2ccc(F)cc2)C(c2ccc(F)c(F)c2)C1 +CCc1ccc(OCC(O)Cn2nnc3ccccc32)cc1 +COc1ncccc1CNC(=O)Nc1nnc(C(C)C)s1 +COC(=O)C1(NC(=O)c2cc(C)oc2C)CCCC1 +CNc1snnc1CN(C)c1cccc(F)c1 +N#Cc1ccccc1NC(=O)CCCOCc1ccccc1 +CCSc1nnc(NC(=O)CCC(=O)c2ccccc2)s1 +COc1ccc(-c2n[nH]cc2Cn2cc(C3CC=CCC3)nn2)cc1 +Cc1ccc(CNC(=O)CCNC(=O)C2CC2C)s1 +CC(C)c1nc(CN2CCCc3cc(F)cc(F)c32)no1 +COc1ccc(NC(=O)c2cnc3cc(C)ccn3c2=O)c(OC)c1 +Cc1cc(F)ccc1NC(=O)N1CCN(C(=O)CCC(C)C)CC1 +CCN(CC)C(=O)CCC(=O)N(CC)c1ccc2ccccc2c1 +Cc1nc(C(N)CO)sc1C(=O)OC(C)(C)C +N#Cc1ccc(NCc2ccc(Br)cc2Cl)nc1 +CCn1ncc2c1CCCC2NCc1cnc(N2CCOCC2)nc1 +CC(c1ccc(S(C)(=O)=O)cc1)N(C)Cc1ccc(F)cc1 +CCOc1ncccc1CN(C)C(=O)Cc1cccnc1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)Cc1ccc(O)cc1 +CCCNC(=O)CSc1nc(-c2ccc(C)cc2)n[nH]1 +COC1CCCC(OC(=O)CCc2ccccc2F)C1 +COc1ccc2c(C)c(CCC(=O)NCCCO)c(=O)oc2c1 +CC1=C(C(=O)OC(C)C)C(c2ccco2)NC(=O)N1 +CCCc1cc(=O)[nH]c2cc(NC(=O)C3CCC3)ccc12 +CC(=O)N1CCN(C(=O)c2ncc(C)c3c(N)cccc23)CC1 +O=C(OCc1cc(F)cc2c1OCOC2)c1cc(-c2ccco2)[nH]n1 +CC(C)c1cc(C(=O)N2CCn3cncc3C2)nc2ncnn12 +O=c1cc(-c2ccncc2)nc(C2CCCN(Cc3ccncc3)C2)[nH]1 +COCCN1CC2CC(C(=O)N3CCOCC3)C(C1)O2 +CNC(=O)NCC(=O)NCc1ccc(OC)c(Br)c1 +COc1ccc2c(c1)NC1(CCCC1)C(=O)N2CCC#N +CCOc1ccccc1C(=O)NCCc1ccsc1 +Cc1nn2cccnc2c1C(=O)N1CCN(CC2CC2)c2ccccc21 +CCCOCC(=O)N1CCCN(C)c2ccc(F)cc21 +Cc1cc(C(=O)OCc2nc3ccccc3[nH]2)cc(=O)[nH]1 +CC(=O)NC(C)(C)c1noc(-c2ccc(NC(=O)NC(C)C)cc2)n1 +CC(C)NC(=O)CNC(=O)COc1ccc2c(c1)CCC2 +Cc1cc(C)c(NC(=O)c2ccc(NS(C)(=O)=O)c(C)c2)c(C)c1 +O=C(NCCO)c1cccc(OCC#Cc2ccc(Cl)cc2)c1 +CNC(=O)N(C)CCc1noc(C2CCCCC2)n1 +Cc1cc(C)n(CC(=O)NCc2c(C)cc(C)[nH]c2=O)n1 +Cc1ccc(-c2nnc(S(=O)CCCC(C)(C)C#N)n2C)cc1 +N#Cc1ccc(CNC(=O)c2ccc(OCC(F)F)nc2)c(F)c1 +Cc1c(Cl)cccc1NC(=O)C(C)NC(=O)c1ccco1 +CC(CNC(=O)Nc1cc(F)ccc1Cl)CC1(C)OCCO1 +O=C(c1ccc(N2CCCS2(=O)=O)cc1)N1CCCC1 +O=C(c1ccc(OC(F)F)cc1)N1CCc2ccccc2C1 +Cc1nc(N)ncc1-c1ncnn1-c1ccccc1 +CCc1nnc(NC(=O)Cc2ccc(Cl)cc2)s1 +Cc1cccc(C)c1NCC(=O)N1CCN(CC(=O)NC(C)C)CC1 +CC(C)Oc1cccc(CC(=O)N2CCN(C(=O)CO)CC2)c1 +Cc1cc(C)n(C(=O)Cc2nnc(-c3cnccn3)o2)n1 +Cc1nnc2n1-c1nnc(C)n1-c1sc3c(c1-2)CC(C)(C)OC3 +Cn1nccc1CNC(=O)Nc1ccc(-c2nnnn2C2CC2)cc1 +Cc1cc(NCc2nc(-c3ccc(F)cc3)n[nH]2)n2ncnc2n1 +CCC(C)NC(=O)C(C)NCc1cccc2ccccc12 +CCN(CC)C(=O)CCC(=O)NC(C#N)c1ccc(F)cc1F +COc1ccc(OCCNC(=O)c2cccnc2N2CCCC2)cc1 +Cc1oc(C(=O)Nc2ccc(Cl)cc2F)cc1S(N)(=O)=O +CC(C)(C)OC(=O)N(CCO)Cc1ccccc1N +COC(=O)CN(C(=O)CCc1cccs1)C(C)C +COCCN(Cc1ccccn1)C(=O)C1CC1c1cccc(Cl)c1 +CCC(CNC(=O)NCCO)Cc1cccc(Br)c1 +CC(=O)N1C(Cn2cncn2)CC2CN(c3ncc(C)cn3)CCC21 +Cn1cc(C(=O)NCC(=O)Nc2ccccc2)c(=O)c2cccn21 +Cc1cc(F)ccc1CCNS(=O)(=O)N1CC(C)CC(C)C1 +O=C1CCCN1CCCNS(=O)(=O)C1=Cc2ccccc2CC1 +CCN(CC)C(=O)c1ccc(NC(=O)CSc2ccccc2)cc1 +CCCC(C#N)NC(=O)CN1CCc2sccc2C1 +CCOc1ccccc1NC(=O)N(C)C(C)CC +O=C(NCCc1ccccc1)N1CCC(Oc2ncccn2)CC1 +NC(=O)CCN(Cc1ccccc1)C(=O)Cn1cccn1 +Cc1ccsc1CNc1cccc(N2CCCNC2=O)c1 +Cc1nc(OCC(=O)NC(C)C)c2c(C)c(C)oc2n1 +CCNS(=O)(=O)c1cc(OC)c(OC)cc1Br +CC(C)COc1ccc(C(C)NS(N)(=O)=O)cc1 +CCc1ccsc1C(=O)OCC1CC(=O)N(C2CC2)C1 +COCCCn1c(-c2ccc(C)c(C)c2)ccc(CO)c1=O +CCCn1nnnc1CS(=O)(=O)c1nnc(-c2ccccc2)n1C +O=C(Nc1cn[nH]c1)Nc1ccccc1S(=O)(=O)N1CCCCC1 +Cc1ccc(NC(=O)C(C)O)cc1Br +O=C(c1cccc(F)c1)N1CCN(Cc2cccs2)CC1 +CCS(=O)(=O)NCCCNC(=O)c1ccc(C)cc1O +CC(COc1ccccc1)NC(=O)C1CCCN(S(C)(=O)=O)C1 +CC(C)C(=O)NCCNC(=O)CCc1ccc(F)c(F)c1 +O=C(NCC(O)c1ccc(F)cc1)c1cc(Cl)ccc1O +O=C(Cc1ccc(Cl)cc1)NCC(O)Cc1ccccc1 +COc1cccc(CN(C)C(=O)CN2CCOC(C)(C)C2)c1OC +O=c1c2nnc3c(-c4ccc(F)cc4)cnn3c2ccn1-n1cnnc1 +C=CCNC(=O)c1ccn(COc2c(Cl)cccc2Cl)n1 +Cc1ccc(C(N)C(=O)NCc2cccs2)cc1 +COc1ccnc(N2CCC(NS(C)(=O)=O)CC2)n1 +CC1CCCC(C)N1C(=O)Cn1c(=O)sc2ccccc21 +CCCCOc1cccc(C(=O)Nc2ccccc2C(=O)NC)c1 +COc1ccc(Br)cc1CNC(=O)c1cnn(C)c1C +Cc1noc2nc(C3CC3)cc(C(=O)Nc3ccc(CCO)cc3)c12 +CCC(Oc1ccc(F)cc1Cl)C(=O)Nc1cc(C)on1 +COc1c(F)ccc2c1CCNC2c1cncc(C)c1 +CC(=O)Nc1cccc(CN2CCCN(C(C)=O)c3ccccc32)c1 +Cc1cc(C(=O)NCCN2CC(C)OC(C)C2)no1 +Cc1nn(C)cc1-c1ccnc(NCc2cc(F)cc(F)c2)n1 +O=C1CCCCCN1Cc1cccc(OC(F)F)c1 +Cc1csc(NC(=O)NCC(O)C(F)(F)F)n1 +COc1cc(Cl)c(C)cc1NC(=O)CSc1ccccn1 +CN(C)C(=O)CNC(=O)CCc1ccccc1Cl +COc1ccc(-c2nc(CN3CC(C)OC(C)C3)co2)cc1 +CCCOc1cc(CNc2nccnc2C#N)ccn1 +COc1cc(Cl)ccc1CNC(=O)C(C)Cc1c(C)n[nH]c1C +CCOC(=O)C(O)c1cccc(CN2CCOCC2)c1 +CCC(C)NC(=O)c1cccnc1SCc1c(C)noc1C +Cc1ccc(NCCNC(=O)Nc2ccccc2)nn1 +CCCC1CN(C(=O)CCc2c(C)nn(CCC#N)c2C)CCO1 +COc1ccc(-c2noc(-c3ccc(-c4cc[nH]n4)nc3)n2)cc1 +Cc1cc(NC(=O)CNc2cc(F)ccc2OC(C)C)n(C)n1 +Nn1c(-c2cccc(F)c2)nc2ccc(F)c(F)c21 +CCOC(=O)c1c(C)[nH]c(C(=O)NCC(=O)NC(C)C)c1C +Cc1cc(CNC(=O)Cc2coc(-c3ccccc3)n2)c(C)o1 +CCc1nccn1S(=O)(=O)c1cc(C(C)(C)C)ccc1OC +Cc1ccc(NC(=O)CSc2nnc(-c3ccncc3)o2)cc1C +CC(c1cccs1)N(C)C(=O)Cn1nnc2ccccc2c1=O +Cc1cc(C(=O)Nc2cc(Cl)ccc2N)c(C)o1 +COC(=O)C(C)Sc1ccc2nnc(-c3ccccc3)n2n1 +CC(=O)c1cc(C(=O)Nc2cc(C)ccc2C)n(C)c1 +CCc1nc(CC(=O)Nn2c(C)nc3sccc3c2=O)cs1 +Cc1nn(C)c2ncc(NC(=O)C(CC(C)C)NC(N)=O)cc12 +CC(C)C(=O)Nc1ccc(C(=O)NCc2nc3ccccc3[nH]2)cc1 +CS(=O)(=O)c1ccc(NC(=O)c2ccc3nccnc3c2)cc1 +O=C(NCc1ccncc1)c1cc(-c2ccccn2)nc2ccccc12 +Cc1nc(CN2CCN(c3ncnc4ccccc34)CC2)no1 +O=c1n(CCOc2ccccc2)nc2ccccn12 +N#CC(c1ccccn1)N1CCC2(CC1)OCCO2 +CCOc1ccc(Cc2nc3cccc(C)n3c2C#N)cc1OC +O=C(Nc1ccccc1OCc1cscn1)c1cc(Cl)c[nH]1 +O=C(Cc1ccccc1)NCCC(=O)Nc1ccc(Cl)cc1 +N#Cc1ccc(OC2CCC(NC(=O)C3CCCOC3)CC2)nc1 +N#CCc1ccc(NC(=O)CNc2ccccc2OC(F)F)cc1 +COC(C)C(=O)Nc1nc2cc(Cl)ccc2n1C +CC(C)c1nnc(NC(=O)CSc2nnc(C3CC3)n2C)o1 +Cc1cccc(C(=O)NC(C(=O)N2CCC(O)CC2)C(C)C)c1 +CC(Nc1cnn(C)c(=O)c1Br)c1ccc(F)cc1F +CCOC(=O)CCC1NCCc2ccc(Cl)cc21 +CC1=NC(CN(C)C(=O)C2CCC(=O)N(CC3CCCCC3)C2)N=C1 +Cc1ccc(S(=O)(=O)n2cnc3ccccc3c2=O)cc1 +C=CCn1c2c(ccc1=O)CC(NS(=O)(=O)c1cn(C)cn1)CC2 +COC(=O)C1(NC(=O)c2csc(-c3cnn(C)c3)n2)CCCC1 +N#Cc1cccnc1OC1CCN(C(=O)c2ccc(F)c(F)c2)CC1 +Cc1ccc(-c2nnn(C(C(=O)NC3CCCC3)C(C)C)n2)cc1 +COc1ccccc1S(=O)(=O)NCCC(O)c1ccccc1 +O=C(c1cc(-c2cccc(O)c2)on1)N1CCCC1 +NC(=O)CC1CCN(C(=O)CCOc2ccccc2F)CC1 +N#Cc1ccc(CNC(=O)N2CCC(CC(N)=O)CC2)cc1 +O=C(NC1c2ccccc2CC1O)c1ccn(C2CCCC2)n1 +Cc1ccccc1SCC(=O)Nc1ccccc1N1CCCC1=O +COc1ccc(CC(=O)NC2CNCc3c(C)cccc32)cc1 +CCNc1cc(C(=O)N(C)Cc2cscn2)ccn1 +O=C(CNC(=O)c1ccccc1)NCc1ccoc1 +CC1CCN(S(=O)(=O)N2CCC(Oc3cnccn3)CC2)CC1 +CC(C)NC(=O)COC(=O)C1(c2cccc(Cl)c2)CCOCC1 +CCc1n[nH]c(SCC(=O)NCCc2ccc(F)cc2)n1 +CC(=O)N1CCc2cc(NC(=O)Cn3ccc(=O)[nH]c3=O)ccc21 +O=C(COc1ccc2c(c1)CCC2)N1CCCC(n2cccn2)C1 +O=C(NCCCOCC1CCCO1)C1COc2ccc(F)cc2C1 +COc1ccccc1OCC1CN(C(=O)Cc2cccs2)CCO1 +COc1ccc2c(c1)nc(-c1ccccc1)c(=O)n2CCC#N +Cn1cnnc1CNC(=O)C(C)(C)c1ccc(Cl)c(Cl)c1 +Cc1n[nH]c(C)c1NC(=O)c1ccc(N2CCCC2)c(F)c1 +Cc1ccc(C(=O)Nc2ccc3ccccc3c2)o1 +N#CC1CN(Cc2ccc(F)cc2OC(F)(F)F)CCO1 +C=CC1NCCc2cc(OCC)c(O)c(Cl)c21 +CC1COC(CO)CN1C(=O)c1cnn(C(C)C)c1C1CC1 +CCCCn1nc(C(=O)N(C)C2(C(=O)OC)CCCCC2)ccc1=O +CC1COCCN1c1ccc(N)c(C(F)(F)F)c1 +COC(=O)c1ccc(F)cc1NC(=O)C1CC=CC1 +Fc1ccc(CN2CCn3c(nnc3C3CC3)C2)c2ncccc12 +CCCC1(CO)CCCN(c2nccc(N3CCC(O)CC3)n2)C1 +CCOc1cc(S(=O)(=O)NC)ccc1Br +Fc1ccc(Nc2ccc3nnnn3n2)cc1Cl +CC(C)Oc1ccc(C(=O)c2ccc(N)cc2)c2cccnc12 +COCCCC1CCCN(C(=O)c2ccnc3ccc(C)cc23)C1 +COc1ccc(-c2nccn2Cc2cccc(N)c2)cc1OC +COC(=O)CCC(=O)Nc1nc2ccccc2s1 +Cc1nc(-c2ccc(F)cc2)cc(N2CCC(O)CC2)n1 +COc1cccc(CNC(=O)Nc2cc3[nH]ccc3cc2C)c1OC +Cc1occc1COC(=O)Cn1c(=O)c2c(ncn2C)n(C)c1=O +CC1CCN(C(=O)c2n[nH]c3ccccc23)C(C)C1 +CCc1cccc(CC)c1NC(=O)C(O)c1ccc(OC)cc1 +Cc1cc(Sc2ccc(S(C)(=O)=O)cc2N)n(C)n1 +CC(Nc1ccn(CC(F)(F)F)n1)c1ccc(S(C)(=O)=O)cc1 +N#CC(NC(=O)C1CCCO1)c1cccc(Br)c1 +O=C(CCCNC(=O)c1cccs1)NCC1CCCCC1 +O=C(Nc1ccncc1)N1CCc2sccc2C1c1cccs1 +O=C(Nc1ccncc1)c1cccc(OCc2ccc(F)cc2)c1 +COc1ccc(OC)c(-c2nc(Cn3cccn3)c(C)o2)c1 +COCCC1(O)CCN(C(=O)c2ccc(OC(F)F)cc2)CC1C +CCC(=O)N1CCN(c2nc3c(Cl)cccc3s2)CC1 +CC(C)CC(C)OCC(=O)Nc1cc(Cl)ccc1N +CC(C)c1nn(C)c2sc(C(=O)Nc3nccn(C)c3=O)cc12 +N#Cc1ccc(NC(=O)c2ccc(F)c(F)c2)nc1 +CCOCCC(=O)N1CCN(Cc2nc3ccccc3[nH]2)CC1 +COc1cc(C)c(CCOC(=O)C(C)N)cc1Cl +Cc1c(C(=O)N2CCOc3ccc(F)cc32)cnn1-c1ccncc1 +Cn1c(C2CC2)nc2cc(NC(=O)C3COc4ccccc4O3)ccc21 +Cc1cccc(-c2nc(-c3ccc(C#N)cn3)no2)n1 +Cc1nn(CC(=O)N2CCCC2)cc1Br +CC(C)Sc1nc(=O)c2cnn(CCO)c2[nH]1 +COC(=O)COc1ccc2c(c1)oc(=O)c1ccccc12 +CCc1cc(=O)[nH]c2cc(NC(=O)Cc3ccccc3)ccc12 +CCOC(=O)Cc1c(C)nn(-c2nc(C)cc(C)n2)c1C +CC(=O)Nc1cccc(NCC(=O)NC(C)(C#N)C2CC2)c1 +COC(=O)c1cn(C)c2ccc(Br)cc12 +Cn1ccnc1Sc1ccc(NC(=O)Cn2ccccc2=O)cc1 +COc1ccc(CC(=O)Nc2noc(-c3ccccc3)n2)cc1 +CCOC(=O)c1cn[nH]c1-c1ccc(Cl)cc1Cl +CCC(OC)C(=O)NCCn1nc2ccccn2c1=O +O=C(CCCc1nc2ccccc2s1)NCCC(=O)N1CCCC1 +COCCNC(=O)CCC(=O)c1cc(C)sc1C +CCn1cc(S(=O)(=O)N2CCc3cncnc3C2)cn1 +Cc1sc2nc(SCCO)n(CC(C)C)c(=O)c2c1C +COc1cccc(CNC(=O)CNC(=O)c2cc3scnc3[nH]2)c1 +Brc1ccccc1C1COc2n[nH]cc2N1 +Cc1ccc(S(=O)(=O)CCOCCC(C)C)cc1C +CNC(=O)NCC(=O)NC(C)c1ccc(-n2ccnc2C)cc1 +COc1ccc(O)c(C(=O)N2CCCC2c2nncn2C)c1 +CS(=O)c1cccc(NC(=O)c2cc3ccccc3c(=O)[nH]2)c1 +CCn1cc(NC(=O)NCC(c2ccccc2)N2CCOCC2)cn1 +CN(CCOCC1CC1)C(=O)c1nc(N2CCCC2)ncc1Cl +O=C(CCn1nnc2ccccc2c1=O)OCC1CCCO1 +OCCc1nc(-c2ccc3c(c2)OCCO3)cs1 +CCn1ccc(C(=O)NC(C)(C)c2nc3c(c(C(N)=O)n2)OCO3)n1 +COC(=O)c1cc2cc(OC)c(OC)c(OC)c2[nH]1 +Cc1cc(F)cc(NC(=O)NCC2CCOCC2)c1 +COc1cccc(-c2ccc(SCC(=O)NC3CC3)nn2)c1 +Cc1ccc(F)cc1NC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 +COc1cc(C(=O)N(CCO)Cc2cccnc2)ccc1F +O=C(Nc1nnc(C2=COCCO2)o1)c1cccc(C(F)(F)F)c1 +Cc1ccc(CNC(=O)Cn2cnc(-c3nc(C)cs3)c2)cc1 +Cc1ccsc1C(=O)NCCNC(=O)C(C)C +CC(C)OC(=O)CCNC(=O)NC1(c2ccc(Cl)cc2)CC1 +Cc1cc(C)cc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)c1 +Cn1cccc1C(=O)NCC(C)(O)c1ccc(F)cc1F +CC(C)C(C#N)N1CCN(c2cccc(Cl)c2)CC1 +NC(=O)C(Cc1ccccc1)NC(=O)Nc1cccc2cnccc12 +Cc1cc(C(=O)NCc2cn(-c3ccccc3)nn2)no1 +NC(=O)CN(CCC1CCCCC1)C(=O)c1ccncc1 +CCC1C(=O)NCCN1Cc1cnc2cnccn12 +CN(Cc1cnn(C)c1)C(=O)Nc1ccc(OCC(F)(F)F)cc1 +CCOc1cc(Br)c(NC(=O)NC(C)C)cc1OCC +CNc1snc(C)c1C(=O)NC1CCOc2ccccc21 +O=c1c2cnc3nc(C(F)(F)F)nn3c2ccn1CC1CCCO1 +COc1ccc(CC(=O)Nc2cc(N3CCC(C)CC3)ncn2)cc1 +O=C(Nc1nnc(C2CC2)s1)c1ccc(-c2cscn2)cc1 +Cc1nnc(SCc2nc3ccc(Cl)cc3c(=O)[nH]2)[nH]1 +N#Cc1ccccc1NC(=O)CCOCc1ccco1 +N#CC(NCC(F)(F)F)c1c(F)cccc1Cl +Cc1ccc(CNC(=O)Cn2cnc3onc(C)c3c2=O)cc1 +Cc1nc(CNC(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)c(C)s1 +COc1ccc(-c2noc(CCCC(=O)N(C)C(C)C)n2)cc1 +COc1ccc(OC)c(NCC(=O)N2CCc3ccccc32)c1 +Cc1cccc(S(=O)(=O)N2CCc3nc(C)sc3C2)c1 +O=C(CCN1Cc2ccccc2C1=O)N1CCCC(c2ccn[nH]2)C1 +COc1ccnc(NCc2nc(-c3ccc(F)cc3)c[nH]2)n1 +COc1ccc(CNc2ncnc(N3CCCCCC3)c2N)cc1 +CSc1nc(C)cc(C(=O)NCC(=O)N2CCOCC2)n1 +CC(C)C(=O)Nc1ccc(OCC(=O)Nc2ccc(F)cc2F)cc1 +O=C(Cc1ccc[nH]1)NC1(c2ccc(Br)cc2)CC1 +CC(C1CC1)N(C(=O)CC1OC(=O)c2ccccc21)C1CC1 +O=C(NCc1cccnc1Oc1cccc(F)c1)N1CCC(O)CC1 +CC(=O)Nc1ccc(C(=O)OC2CC(C)OC2=O)cc1 +CC(Sc1nnnn1C(C)C)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +Fc1ccc(F)c(NCc2ccncc2Cl)c1 +CN(C(=O)CCNC(=O)C1CCCC1)c1nccs1 +COC(=O)CC(C)NC(=O)c1ccccc1Cl +COc1ccc(C)cc1NC(=O)C1CCCN(C(=O)C(C)(C)C)C1 +COCCN(CC(C)C)C(=O)Cc1csc(C)n1 +COc1ccccc1CNC(=O)COn1nnc2ccccc21 +O=C(NC1CC1)c1nc(C2CC2)nc2c1OCCO2 +O=C(CNC(=O)Nc1ccccc1)NCc1ccccc1 +CCCC(=O)Nc1cc(OCC)c(N)cc1OCC +CCCC1CN(C(=O)c2csc(-c3ccoc3)n2)CCO1 +COc1ccc(C)cc1NC(=O)Nc1cc2[nH]c(=O)[nH]c2cc1C +CCOc1cc(CCC(=O)N2CCN(CC)CC2)cc(N)c1O +CC1CN(C(=O)CSc2nnc(-c3ccco3)n2N)CC(C)O1 +Nc1cccc2c(Br)cnc(NCc3ccco3)c12 +Cc1ccc(C(=O)CCC(=O)N(C)CCC#N)cc1 +Cc1nnnn1-c1cccc(NC(=O)N2CC(C)CC(C)C2)c1 +CC(C)c1ccc(NC(=O)CN(C)CCN2CCOCC2)cc1 +CNC(=O)CNC(=O)c1cc(=O)oc2cc(OC)ccc12 +C=C(CN1CC(C)OC(C)C1)C(O)c1ccccc1 +O=C(c1ccc[nH]c1=O)N(Cc1cccs1)Cc1cccs1 +COc1ccccc1-c1noc(CNC(=O)c2ccc(C)cc2)n1 +O=C(OCn1nnc2ccccc2c1=O)c1c(F)cccc1Cl +CCCOc1cccc(NC(=O)NC2CCCc3occc32)c1 +COc1ccccc1C(C)Nc1cccc(C#N)c1 +Nc1cc(NC(=O)c2cccc(Br)c2)c(F)cc1F +Cc1ccsc1C(=O)N1CCc2ncnc(C)c2CC1 +C=CCNc1nnc(Sc2ccc3nccnc3n2)s1 +CCNC(=O)c1ccc(NCC(=O)N2CCOCC2)c(C)c1 +COC(=O)c1cc(C(=O)N(C)Cc2c(F)cccc2Cl)ccn1 +Nc1ccc(-c2nc(-c3ccc(O)cc3)no2)cc1 +Cn1cc(CN2CCC(F)(F)C3(CCN(c4cnccn4)C3)C2)cn1 +Cc1nsc(N2CCCN(C(=O)NCC3CC=CCC3)CC2)n1 +CC(=O)NCC(=O)NCc1ccc(CN2CCc3ccccc32)cc1 +COc1cc(CNC(=O)c2ccc(F)cc2Cl)ccn1 +CC(C)(C)C(=O)Nc1cccc(C(=O)Nc2c[nH]c(=O)[nH]c2=O)c1 +O=C(COc1ccccc1O)Nc1nc(-c2ccc(F)cc2)cs1 +Cc1c(C(=O)OC(C)C)nnn1-c1ccc(F)cc1 +Cc1sc2nc(CSc3ccccc3)[nH]c(=O)c2c1C +COc1cc(C(=O)NCCCNS(C)(=O)=O)cc2c1OCCO2 +COc1cc2c(cc1O)CCNC2c1ccncc1Cl +CC(C)CS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +NC(=O)c1cccc(OS(=O)(=O)c2ccccc2)c1 +O=C(Nc1ccc(N2CCCC2)nc1)c1ccc(O)c(Cl)c1 +Cc1ccsc1CNC(=O)CSc1nnc2n1CCCCC2 +CCN1CCN(S(=O)(=O)c2ccc(N)cn2)CC1 +COc1cccc(C2CC(=O)Nc3c2ccc(C)c3C)c1OC(C)C +COc1ccc(OCCn2nnc(-c3ccccc3)n2)cc1 +CCOc1cc(C)c(Cl)cc1S(=O)(=O)NCCOC +Cc1nnnn1-c1ccc(CC(=O)NCCc2ccccn2)cc1 +CN(C)C(=O)CSc1nnc2c(n1)[nH]c1ccccc12 +CCc1ccc(CN(CCC#N)Cc2ccccn2)o1 +Cc1ccc(CN(C)C(=O)c2ccnc3ccccc23)o1 +Cc1nn2c(CCc3ccc(Cl)c(N)c3)nnc2s1 +NC(=O)c1csc(C(=O)Nc2ccc(-n3cccn3)cc2)c1 +O=C(NC1CCN(C(=O)c2ccc(F)cc2)CC1)c1ccc[nH]1 +CCC(C)C(=O)Nc1ccc(N2CCCC2=O)cc1 +Cc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1S(C)(=O)=O +Cc1cccc(NC(=O)NCCc2nnc3n2CCC3)c1Cl +CCCCC(=O)Nc1ccc(O)c(-c2nc3cnccc3o2)c1 +CCc1nnc2n1CC(NC(=O)Cn1ccc(=O)n(C)c1=O)CC2 +Cc1ccc(S(=O)(=O)CC(=O)N(C)C(C)c2ccccc2)cc1C +O=C(NC1CCSc2ccc(Cl)cc21)c1cnccn1 +CCc1nn(CCO)c(N)c1-c1nc2ccccc2[nH]1 +O=C(Cn1ccccc1=O)N(Cc1ccco1)CC1CCCO1 +Cc1nccc(N2CCCC(c3[nH]ncc3S(C)(=O)=O)C2)n1 +c1cc(NCc2ccsc2)cc(N2CCCC2)c1 +Fc1cc2c(c(F)c1F)CCNC2C=Cc1ccncc1 +O=C(NCc1ccc(-n2cnc3ccccc32)cc1)C1CCOCC1 +COCc1ccc(C(=O)Nc2cc3c(cc2Cl)OCCO3)o1 +CS(=O)(=O)c1ccc(NC(=O)C23CC4CC(CC(C4)C2)C3)cc1 +O=C(C1CCCO1)N(Cc1ccccc1)Cc1ccco1 +Cc1occc1C(=O)N1CCCC2(CCN(c3cccnc3)C2=O)C1 +CCOCCCC(=O)Nc1ccc(Cl)c(Br)c1 +Cc1cccc(CCNS(=O)(=O)c2ccccc2C#N)c1 +COc1ccc(-c2ccc(=O)n(CC(=O)C(C)(C)C)n2)cc1OC +CC(C)c1nn2c(N)c(C#N)nnc2c1-c1ccc(F)cc1 +Cc1noc(CCCC(=O)NC2CCCCNC2=O)n1 +COCc1cccc(NC(=O)NCCCc2cn[nH]c2C)c1 +Cc1cc(CS(=O)(=O)NC(C)C(=O)N2CCCCC2C)no1 +N#CC(NC(=O)c1ccc(-n2ccnn2)cc1)c1ccc(Cl)cc1 +COC(=O)c1c(NC(=O)c2cc(C)n(C)n2)sc(C)c1C +COc1ccc(Cl)cc1C(=O)NCc1cc(-c2ccco2)n(C)n1 +O=C(COC(=O)CCc1nc2ccccc2s1)NC1CCCC1 +COCCn1cnnc1SC(C(=O)N1CCCC(C)C1)C(C)C +COC(=O)c1oc(CSc2nncn2C(C)C)cc1C +CC1=NC(c2cccc(CN(C)Cc3nnc(C)o3)c2)=NC(=O)C1C +COc1ccc(NC(=O)C(C)Sc2ccc(N)nc2)cc1Cl +COc1cc(OC)c(NC(=O)C2CNC(=O)C2)cc1Cl +CNc1snc(C)c1C(=O)NCC1(c2ccc(F)cc2)CC1 +O=C1N(CC2CCCCO2)CCN1c1ccc2c(c1)CCC2 +COC(=O)c1ccc(F)c(NC(=O)Cc2cccc(OCC#N)c2)c1 +CCc1ccc(S(=O)(=O)Nc2ccccc2C(C)=O)cc1 +CN(Cc1cc(-c2ccccc2)no1)C(=O)c1ccc2nonc2c1 +O=C(Nc1ccccn1)C1CSc2nccc(=O)n2C1 +CCOc1cc(CNC(=O)c2cccc(-c3nnc(C)o3)c2)ccn1 +Cc1cccc(N2CCN(C(=O)Nc3ccccc3)C(C)C2=O)c1 +CCOCCNC(=O)N1Cc2ccccc2N(C)CC1CC +CCCc1cnc2c(c1SCCOC)c(=O)n(C)c(=O)n2C +CCOc1cc(C)c(C(O)CNCc2cccnc2)cc1C +COc1ccc(COc2ccccc2C(N)=O)cc1 +O=C(NCC1CCC1)c1ccc2c(c1)OCCCO2 +Cc1cc(C(=O)Nc2ccccc2-c2ccccc2)[nH]n1 +CCC(CC)NC(=O)c1ccc2c(c1)C(c1nc[nH]n1)CN2C(C)=O +CCC1C(=O)NCCN1Cc1csc(C(C)C)n1 +CC(=O)c1csc(CCOc2ccc(C)cc2)n1 +Fc1ccc(COc2ccc(-n3cnnn3)cc2)cc1F +Cc1ccc(C)c(NC(=O)c2cc3ccccc3[nH]c2=O)c1 +Cn1c(SCC#N)nc2cc(-c3ccccc3)sc2c1=O +COC(=O)NCc1ccc(NCc2nsc(N(C)C)n2)cc1 +O=S(=O)(Nc1ccc2c(c1)CCCC2)c1ccc2c(c1)OCCO2 +CN(C)C(=O)CNS(=O)(=O)c1c(N)cc(Cl)cc1Cl +COc1cc(NC(C)=O)ccc1-c1ccc(CO)o1 +CC(=O)NC(CC(=O)Nc1ccnn1CC(C)C)c1ccccc1 +CN(C(=O)Nc1nnc(C2CC2)s1)C1CCCCCC1 +CCOC(=O)N1CCN(C(C)C(=O)N2c3ccccc3CC2C)CC1 +COC(=O)c1ccc(C(=O)N=c2[nH]c3ccccc3[nH]2)nc1 +CC(O)Cn1c(CCCO)nc2cc(C(F)(F)F)ccc21 +Nc1cc(C(F)(F)F)ccc1NC(=O)CCCO +CCCNC(=O)Nc1cccc(OCc2nc(C)cs2)c1 +COc1ccc(Cn2nc(C)n(-c3ccc(Cl)cc3)c2=O)cc1 +CC(C)(C)c1ccc(C(=O)N2CCN(c3ncccn3)CC2)cc1 +N#Cc1cccc(CNC(=O)NCCc2c[nH]c3cc(F)ccc23)c1 +CN(C)C(=O)CSc1nnc2c(n1)[nH]c1ccc(F)cc12 +CC(C)c1nc2c(NC(=O)Cc3ccsc3)cccn2n1 +O=C(NC1(c2ccccc2)CCOCC1)c1cccnc1 +CCn1c(=O)n(CC(=O)NCCOC)c2cccnc21 +CCn1ccc(NS(=O)(=O)c2ccc(Cl)cc2)n1 +COc1ccc(Cl)cc1CN1CCOC(c2nc(C)n[nH]2)C1 +CC(=O)Nc1ccc(SCC(=O)Nc2ccc(C)c(F)c2)cc1 +CCc1oc2ccccc2c1CN(C)C(=O)c1c(C)cc(C)[nH]c1=O +Cc1ccc(OCCC(=O)NC2CCCc3occc32)cc1C +O=C(Cn1cncn1)NC1CCc2c(Cl)cccc21 +CC(=O)NCC(=O)N1CCN(c2cccc(Cl)c2)CC1 +Cc1noc2nc(C(C)C)cc(C(=O)NCc3cccc(F)c3)c12 +COCCN1CCN(C(=O)c2cc3ccc(C)cc3[nH]2)CC1=O +NC(=O)C(Sc1ccc(Cl)cc1)c1ccccc1 +Cc1nnc(SCc2nc(C3CC3)nn2-c2ccc(C)c(C)c2)o1 +Cc1cc(CSc2ncccc2C(=O)Nc2ccccc2O)no1 +CCNc1nc(NCC(C)(C)C#N)nc(SC)n1 +N#CCCN(CCC(F)(F)F)C(=O)c1ccccc1Br +COc1ccnc(NC(=O)c2ccc(N(C)C)cc2)c1 +CCC(C)N(Cc1ccccc1)C(=O)c1ccccc1S(C)(=O)=O +Cc1ccc(Cl)cc1NC(=O)NCC(=O)NC(C)(C)C +CCNC(=O)N1CCN(C2CCCN(c3cnn(C)c3)C2=O)CC1 +CN(C(=O)C1CC(=O)N(Cc2ccco2)C1)c1cccc2ncccc12 +CC(CNC(=O)c1cc(C2CC2)nn1C)c1ccc(F)cc1 +CCn1cc(-c2nn3c(-c4ccccc4)nnc3s2)c(C)n1 +CC(C)n1ccc(-c2nnc(NC(=O)c3ccc4ccccc4c3)o2)n1 +COc1ccc(Cl)cc1NC(=O)Nc1ccc2c(c1)CC(=O)N2C +CCOC(=O)c1cnn(-c2nc3ccccc3nc2C)c1N +COc1cc(NC(=O)CSc2nnnn2C)cc(OC)c1OC +CCc1onc(C)c1NC(=O)NCCc1ccncc1C +CN(Cc1ccsc1)C(=O)CCc1c[nH]c2ccccc12 +Nc1nc(-c2ccccc2)ncc1C(=O)Nc1ccccc1F +COc1ccc(NC(=O)c2ccc(C)c(F)c2)c(N)c1 +Cc1nnsc1C(=O)Nc1nc(-c2ccc(F)cc2)cs1 +CCCC1CN(C(=O)CCCS(=O)(=O)N2CCCC2)CCO1 +CC(=O)NC(C(=O)N(C)CCOc1ccccc1C)C(C)C +COCC1CN(Cc2nccs2)Cc2nn(C)cc21 +O=C(Cc1ccc(F)cc1F)NCc1ccnc(OCC2CC2)c1 +CC(=O)C1CC(CC(=O)OC(C)c2cccnc2)C1(C)C +CC(=O)c1ccc(NC(=O)N(C)CC(C)(C)O)cc1C +CCn1cc(NS(=O)(=O)c2cc(Cl)ccc2Cl)cn1 +CNC(=O)c1cccc(NC(=O)c2cccc(OC)c2F)n1 +Cc1cc(OCCn2nncc2-c2cccs2)ccc1N +CCCCn1nc(C(=O)Nc2cc(C)c(Cl)cc2OC)ccc1=O +Cc1nncn1CCNC(=O)c1ccc(C(=O)Nc2ccccc2)cc1 +Cc1csc(C(C#N)C(=O)c2ccc(Br)cc2)n1 +CN1c2ccc(Cl)c(N)c2C(C)(C)S1(=O)=O +CNC(=O)c1ccccc1NC(=O)c1cccc(S(C)(=O)=O)c1 +O=C(Oc1ccc(OCc2ccncc2)cc1)c1ccsc1 +CC(NC(=O)c1cnc2ccccn2c1=O)c1cccc(Cl)c1 +CN(C)S(=O)(=O)NCC1(c2ccc(Br)cc2)CCC1 +CC(C)(C)c1ccc(SCC(=O)OCc2nc(N)nc(N)n2)cc1 +O=C(COc1ncnc2ccccc12)Nc1ccc(F)cc1F +N#Cc1cc(C#N)c(SCC(=O)c2ccc(F)c(F)c2)nc1N +COCc1cc(C(=O)NC2(c3noc(C)n3)CCCC2)ccc1F +Cc1ccc(N2CCN(CC(=O)N3CCNC(=O)C3)C2=O)cc1 +Cc1cc(CN2CCN(C(=O)c3ccc(N(C)C)nc3)CC2)on1 +CCc1nc(COc2ccc(C(C)=O)cc2)cs1 +CSc1nc(C)c(CCC(=O)N2CCc3sccc3C2)c(C)n1 +CN(CCc1ccccn1)Cc1cccc(C(F)(F)F)c1 +COC(=O)c1cc(N)ccc1OCC1CCOC1 +CN(Cc1cccc(F)c1)S(=O)(=O)c1ccc2c(c1)OCCO2 +O=C(CCc1ccccc1)Nc1ccn(CCc2ccncc2)n1 +CCOC(=O)c1cnn(C2CCCN(C(=O)CCC3CCCC3)C2)c1 +CC(C)CNC(=O)c1cc2c([nH]c1=O)CCCC2=O +O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1cc(=O)[nH]c2ccccc12 +Cc1cnc(NC(=O)NCC(=O)Nc2ccc(F)c(F)c2F)s1 +Cc1csc(=O)n1CCC(=O)NCc1ccc(C(C)(C)C)cc1 +Cc1ccc(OC(C)C(=O)OCC(N)=O)c(Br)c1 +COc1ccc(-c2cn(-c3cccc(N)c3)nn2)c(C)c1 +COc1ccc(C)cc1NCc1nnc(-c2ccc(F)cc2)o1 +Cn1cccc1C(O)CNC(=O)c1cccc(C#N)c1 +CCc1nc(CN2CCCN(c3nnc(C)c(C)c3C#N)CC2)no1 +Cc1nc(CNC(=O)c2cc3cccc(F)c3o2)nc2ccccc12 +CC(=O)c1ccc(N2CC(CO)C(CN3CCOCC3)C2)nc1 +Oc1ccc2c(c1)OCC2Nc1ccccc1Cl +O=C(Nc1nnc(-c2ccccc2)o1)c1ccccc1F +O=C(Nc1cccc(-c2nc(C3CC3)n[nH]2)c1)c1c[nH]c2ncccc12 +CNS(=O)(=O)c1ccc(NCCC(=O)N(C)C)cc1 +CC(=O)c1ccc(Sc2nccn2C)c(F)c1 +N#Cc1ccc(NC(=O)CCn2cccnc2=O)cc1 +Cc1noc(CCC(=O)NC(C)c2ccc(F)c(Cl)c2)n1 +O=C(NCCOc1ccccc1)C1COc2ccc(F)cc2C1 +Cc1cc(C(=O)N2CC(C)C3(CCN(c4ccsc4)C3=O)C2)no1 +CCCC(C)NC(=O)C1CCCN(C(=O)C(CC)CC)C1 +CCn1nc(C)cc1C(=O)Nc1nnc(-c2cccc(Cl)c2)o1 +CC(CC1CCCC1)C(=O)NC1CCN(C(=O)c2ccoc2)CC1 +CN(CC1CCCC1)C(=O)c1sccc1NS(C)(=O)=O +CS(=O)(=O)c1ccc(C(=O)NCc2cccs2)cc1 +CCC(C#N)Oc1cccc(CNC(=O)c2cccc(OC)c2F)c1 +CC(Cn1cccn1)NS(=O)(=O)c1cccc(Cl)c1F +CCn1c(Cc2ccccc2)nnc1S(=O)(=O)Cc1cc(C)on1 +CCc1ccc(C(C)NS(=O)(=O)c2sc(=O)[nH]c2C)cc1 +O=C(CSc1ccc(NC(=O)C2CC2)nn1)c1ccccc1 +CCNC(=O)c1cc(-c2ccccc2Cl)no1 +Cc1c(C)c2ccc3c(c2oc1=O)CN(C1CC1)CO3 +Cc1ccc(C)c(N2CCN(C(=O)C3CC3)C(C)C2=O)c1 +CN(C(=O)c1cnc(-c2ccco2)nc1N)C1CCCCC1 +COC(=O)N1CCC(NC(=O)c2[nH]c3ccccc3c2Cl)CC1 +O=C(NCCNC(=O)C1CCCO1)c1cccnc1 +Cc1cnc(C(=O)N2CC(C)c3ccccc32)cn1 +Cn1cc(C2CC2C(=O)N2CCN(c3ccc(C#N)cn3)CC2)cn1 +CCOC(=O)N1CCCC(C(=O)Nc2cccnc2)C1 +CC(C)CC(=O)Nc1ccc(-n2cncn2)c(F)c1 +COc1ccccc1CC(=O)NCCCn1ccnc1 +c1ccc(-n2nnnc2SCC2CCCCO2)cc1 +CC(C)(C)NC(=O)CSc1nc(C=Cc2cccs2)n[nH]1 +Cc1sc2nc(-c3ccc4c(c3)OCO4)[nH]c(=O)c2c1C +Cc1cc(SC2CCCCC2)ccc1NC(=O)Cn1cncn1 +Nc1ccccc1-c1csc(-c2cccnc2)n1 +Cc1ccc(C(=O)N2CCN(c3ccc(O)cc3)CC2)c(C)c1 +CC(C)CCNC(=O)c1ccc(OCC2CCCO2)cc1 +O=C(OCCCc1cccnc1)c1cc(=O)[nH]c2ccccc12 +COc1ccc(CCNC(=O)CCc2ccsc2)cc1 +CCc1ccccc1OC(=O)c1cc(C(N)=O)cs1 +CC(CNS(=O)(=O)c1ccc2c(c1)NC(=O)CO2)n1cncn1 +CC(C)(C)OC(=O)NCCC(=O)Nc1ccc(Cl)cc1F +CC(C)C(=O)N1CCN(c2cc(N3CCOCC3)ncn2)CC1 +COCCNC(=O)NC(CC1CCCCC1)c1ncccn1 +COc1cc(CN(C)C(=O)c2cccc(OC)c2F)ccc1SC +CCN(C(=O)NC1CCCN(Cc2ccccc2)C1=O)C1CC1 +C=C(C)CN(CC)C(=O)CN(CC)c1ccccc1 +COc1ccc(C(O)CN2CCc3ccccc32)cc1C +CC(C)CNC(=O)c1ccccc1NC(=O)C(C)c1ccsc1 +CCCCNC(=O)C1CCC(C)N(C(=O)CSc2ccncc2)C1 +CCOCCCC(=O)NCc1cn2cc(Br)ccc2n1 +COc1cccc(CNC(=O)c2cc3cc(=O)[nH]cc3[nH]2)c1 +COC(=O)c1cc(COc2ccccc2OC)c(C)s1 +CC1CCN(C(=O)c2c(O)cc(F)cc2F)CC1 +Cc1ccc(F)c2c1CCCN2Cc1cc(=O)n2nccc2[nH]1 +CCOc1ccc(NC(=O)c2cnc3ccc(C)cn23)cc1F +CC12CCC(C(=O)NCC3CCCO3)(OC1=O)C2(C)C +COc1cccc(CC(=O)N2CCN(C(=O)C3CCCCC3)CC2)c1 +Cn1cc2ccc(F)c(C(O)c3ccncc3)c2n1 +CC(=O)c1c[nH]c(C(=O)N2CCCN(C(=O)OCC(C)C)CC2)c1 +O=C(C1CC1)N1CCN(Cc2ccc(Br)cn2)CC1 +CC(NC(=O)CN(C)C(N)=O)c1ccccc1C(F)(F)F +CC#CCOc1ccc(S(=O)(=O)N2CCCCC2)cc1 +O=C(NCCN1CCOCC1)c1cc2cccc3c2n(c1=O)CC3 +CCN(Cc1ccc(C(=O)N(C)C)cc1)C(=O)Nc1cccnc1 +O=C(NCc1cccnc1)N1CCC(c2cc3ccccc3[nH]2)CC1 +Cc1c(C(=O)NC2c3ccccc3Oc3ccccc32)cnn1C +COCC(NC(=O)C1CC1c1ccc(F)cc1F)C(N)=O +O=C(Nc1ccc(-n2cccn2)cc1)c1cccnc1 +O=C(COc1ccccn1)NCCOc1cccc(Cl)c1 +Cc1nc(OCCNC(=O)c2ccccc2F)cc(N2CCCC2)n1 +C=CCN1C(=O)CCC12CCCN(C(=O)c1ccc[nH]1)CC2 +Cc1nccn1-c1ccc(CNC(=O)NCC2CCCC(C)C2)cn1 +Cc1ccc(C(=O)Nc2c[nH]cc(Br)c2=O)c(C)c1 +CNC(=O)CN(C)C(=O)C1(c2ccccc2)CCC1 +Cc1cccc(-n2ccnc2S(=O)(=O)CCCS(N)(=O)=O)c1 +CC(C)CC(C)OC(=O)c1cccc(S(C)(=O)=O)c1 +O=C(Cc1csc(-c2nc[nH]n2)n1)Nc1ccc2c(c1)COC2 +CCOCCC(=O)Nc1cc(Cl)ccc1C(N)=O +O=C(CCCCCn1nnc2ccccc2c1=O)N1CCCCCC1 +C=CCn1nnnc1NCc1ccc(-c2ccc(Cl)cc2)o1 +CCn1cc(CNS(=O)(=O)c2cc(F)ccc2F)c(C)n1 +CCOc1ccc(C(=O)N2c3ccccc3CC2C(=O)NC)cc1 +O=C(NCC1CCCO1)c1ccc(-n2cnc3cccnc32)cc1 +CC(=O)c1cccc(NC(=O)c2cc3occc3n2C)c1 +CCOC(=O)c1sc(-c2ccco2)c(CC)c1N +C#CCNC(C)(C(=O)OC)c1ccc(OCC)cc1 +Cc1c(C(=O)Nc2cccc(C(N)=O)c2)cnn1-c1ccccc1 +CCNC(=O)c1ccc(CNC(=O)Cn2ccc3ccccc32)cc1 +CCn1nnc2c(N3CC(C(=O)Nc4ccccc4C)C3)ncnc21 +CC(Nc1ccc(CC#N)cc1)C(=O)N(C)CCC#N +COCCCN1CC2(CCCN(c3nccc(OC)n3)C2)CCC1=O +CN(C)C(=O)COCC1CN(Cc2cccnc2)Cc2cncn2C1 +CC(O)CN1CCN(C(=O)CCc2ccccc2)CC1 +O=C(OCC#Cc1ccccc1)C1CC(=O)N(CC(F)(F)F)C1 +O=C1c2ccccc2S(=O)(=O)N1Cc1cc(=O)n2ccsc2n1 +Nc1ccccc1OCCCOc1cccc2cccnc12 +CC(C)(C)OC(=O)NCCOc1ccccc1N +O=C(CSc1nnc(-c2ccco2)o1)Nc1ccc(F)c(F)c1 +Cc1ccc(-c2cc(C(=O)NCCn3nc(C)c(Cl)c3C)[nH]n2)o1 +CCOCC(=O)N1CCC(c2cccs2)CC1 +CCCC(=O)Nc1ccc(NC(=O)NCc2ccco2)cc1 +CC(C)CCNC(=O)C1(C)CCC(=O)N1CCC(C)C +Cn1cc(NC(=O)c2cccc3ccccc23)c(=O)n(C)c1=O +Cc1ccc(C(=O)NCc2nc(-c3ccccc3C)no2)cc1 +CCOC(C)c1noc(CN2CCOC(c3ccccc3)C2)n1 +CCNc1nc2c(c(=O)[nH]c(=O)n2CCCOC)n1CC +Cc1cccc(C)c1-n1nnnc1Cn1ccc(C)c(C#N)c1=O +NC(=O)CSc1nnc2n1-c1sc3c(c1-c1ncnn1-2)CCC3 +COC(=O)Cc1csc(NC(=O)Cc2ccccc2Cl)n1 +CC(C)CNC(=O)CCNC(=O)Cc1cn2c(nc1=O)SCC2 +[H]N=c1n(CC)c2ccccc2n1CCOc1ccc(F)cc1 +Cc1cc(C)cc(OCC(=O)NCCc2nc3ccccc3[nH]2)c1 +O=C(NCCNc1cnccn1)c1cnc(-c2ccccc2F)s1 +COc1cc(C)c(-c2cc(C#N)c(N)[nH]2)cc1Cl +COc1cccc2cc(C(=O)Nc3cc(C)ccn3)c(=O)oc12 +O=C(NCc1ccccc1)c1cc2ccccc2nn1 +COc1cccc(-c2nnc(NC(=O)Cc3ccccc3)o2)c1 +CC1CN(C)CCN1C(=O)C1CCN(S(N)(=O)=O)CC1 +Cc1ccccc1NC(=O)c1ccc(S(N)(=O)=O)o1 +O=C(Cn1ccc2sccc2c1=O)Nc1ccc(Cl)cc1F +CCN(CC(C)C#N)C(=O)CNc1ccc(F)c(C(=O)N(C)C)c1 +CCCn1nc(C(=O)NCC(=O)NC2CC2)ccc1=O +O=C(Cc1c[nH]c2ncccc12)NCCc1nc(-c2ccccc2)n[nH]1 +CN(C(=O)c1cnccn1)C1CCN(C(=O)OC(C)(C)C)CC1 +CC(C)n1ccc(-c2nnc(NC(=O)COc3ccc(F)cc3)o2)n1 +CC(C)(C)CS(=O)(=O)NCCNC(=O)c1ccccc1 +Cc1cc(C(=O)Nc2cc(Cl)ccc2N(C)C)on1 +COc1ccc(O)c2c1C(c1ccc(CO)cc1)NCC2 +N#Cc1ccc(N2CCC(C(=O)Oc3cccc4[nH]ncc34)CC2)nc1 +Cc1cc(C)cc(CC(C)NS(=O)(=O)N2CCOCC2)c1 +Cc1nc2ccccc2c(=O)n1CCC(=O)NC(C)C1CCCO1 +Cc1cc(C)n(-c2ccc(NCc3nc(C)no3)cc2F)n1 +COc1ncccc1CNC(=O)Nc1ccnn1C1CCCCC1 +CCc1ncc2c(n1)CN(C(=O)c1cc3cccc(Cl)c3n1C)C2 +COc1ccc(C(C)OC(=O)CN(C)C(=O)c2ccccc2)cc1F +Cc1ccc(NCC(=O)Nc2c(C)nn(C)c2C)cc1 +CCN(CC1CCCO1)C(=O)CCCc1ccccc1 +Cc1ccc(C2CC2C(=O)Nc2cc(C(N)=O)n(C)c2)s1 +Cc1ccn2cc(C(=O)N3CC(CO)CCC3C)nc2c1 +CC(=O)c1ccc(NC(=O)NC2CCN(C(C)=O)C2)cc1C +COC(=O)C1CCCN(Cc2cnc(-c3ccsc3)s2)C1 +C=CCSc1nnc(-c2ccccc2Br)n1N +CCNc1nc(SCC(=O)OC)nc2ccccc12 +COCc1ccc(C(=O)OC(C)c2nc3ccccc3c(=O)[nH]2)cc1 +CN(CCOCC1CC1)C(=O)Cn1cnc2c(cnn2C)c1=O +CCCc1nc(C(=O)NCc2nc3ccccc3c(=O)[nH]2)cs1 +Cn1c(=O)ccn(CC(=O)OC2CCCC2)c1=O +CCC(C)N(Cc1ccncc1)C(=O)c1cccc(=O)[nH]1 +COc1ccc(NC(=O)c2cc(-c3ccc(C)cc3)n[nH]2)cc1OC +O=C(c1ccc(=O)n(Cc2ccc(F)cc2)n1)N1CCCC1 +N#Cc1ncn(-c2nc(-c3cccnc3)nc3sc4c(c23)CCC4)n1 +CC1CN(C(=O)CSc2ncn[nH]2)CC(C)O1 +CC(=O)c1cc(Br)ccc1NC(=O)C1CCCO1 +C#CCNCCn1c(C)c(Br)c2ccccc21 +COC(=O)C1=C(C)Nc2nnnn2C1c1cccs1 +CCN(CC(=O)c1c(C)[nH]c(C(=O)OC)c1C)C(=O)c1cccs1 +CN(C)c1cc(-c2ccc(C(C)(C)C#N)cc2)ncn1 +NC(=O)c1ccc(C(=O)OCc2ccccc2C(F)(F)F)cc1 +COC(=O)N1CCCC1C(=O)NCC(C)(O)c1ccc(F)cc1 +COCCN(Cc1sccc1C)C(=O)Cc1cc(C)no1 +CCCn1cc(C(=O)N(C)C(COC)c2ccccn2)c(C)n1 +COc1cccc(NC(=O)C(C)OC(=O)C(C)C)c1 +CCCCNC(=O)c1cccc(Oc2cnccn2)c1 +CC(=O)N1CCCC(c2ncc(C(=O)Nc3ccccc3)c(C)n2)C1 +O=C(CN1CCCCC1=O)Nc1ccc(Oc2ncccn2)cc1 +CCc1ccc2nc3c(c(C(C)=O)c2c1)CN(C)CC3 +O=C(NCCNC(=O)c1ccccc1O)c1ccsc1 +CC(C)c1cc(Br)ccc1NCc1nc(C2CC2)no1 +Nc1ccc(-n2ccnc2-c2ccccc2)c(F)c1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)Nc1cccc2cn[nH]c12 +Cc1cc(NC(=O)CCSc2ccccc2)on1 +Cn1c(=O)c2c(nc3n2CCCN3CC(=O)C(C)(C)C)n(C)c1=O +COC(=O)NCC(=O)Nc1ccc2oc(=O)ccc2c1 +CCCCOc1ccc(-c2cc(NC)nc(C)n2)cc1 +O=C(Nc1ccc(N2CCCCC2)nc1)c1ccc(-n2cncn2)cc1 +CC1CC(C)CN(C(=O)CNc2cccc(OCC(=O)N(C)C)c2)C1 +CC(C)(C)C(O)CCNC(=O)C1(c2cccs2)CCCC1 +Cc1nc2c(s1)CCCC2Nc1nc2c(s1)c(C)nn2C +CC(C)C(NC(=O)NCc1nnc2n1CCC2)c1cccs1 +Cc1csc(CCNC(=O)COc2c(C)cccc2C)n1 +COC(=O)N1CCC(NC(=O)c2cc3ccc(C)cc3nc2C)CC1 +CCC(=O)Nc1ccc(Oc2ccccc2)cc1N +Cc1cc(C)cc(-n2ncc(C(=O)N(CCO)CC(F)(F)F)n2)c1 +CCn1nc(C(C)C)cc1C(=O)N(C)CCCc1cnn(C)c1 +Cc1cc(S(=O)(=O)Nc2cc(N)ccc2C)ccc1F +CCc1noc(C)c1C(=O)N1CCCC1c1nc2ccccc2s1 +CSc1ncc(C(=O)OC(C)C(N)=O)n1-c1ccccc1 +CCOC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)ns1 +Cc1cccc(C)c1OCCNC(=O)N1CCC(C(N)=O)CC1 +CC(C)c1ccccc1N1C(=O)c2ccccc2NC1(C)C +Cc1ccc(OCCNC(=O)c2cc3ccccc3c(=O)[nH]2)cc1 +Cc1cc(C)n(CCCN(C)C(=O)C2CCCO2)n1 +COCc1ccc(C(=O)Nc2c[nH]cc(Br)c2=O)o1 +O=C(Cn1cc(Cl)cn1)Nc1ccc(OC(F)(F)F)cc1 +COc1ccccc1CN(Cc1cccs1)C(=O)C1CCC1 +Cc1cc(C(=O)NCc2cccc(C(N)=O)c2)sc1C +Cc1cc(N2CC(C(=O)NCCO)CC2=O)ccc1Br +CC(C)CCN(CCC#N)Cc1cccc2c1OCCCO2 +N#Cc1ccc(C(=O)N2CCCC2C2CCCC2)cc1 +Cn1cc(CC(=O)Nc2ccc(Cl)cc2OCC(F)(F)F)cn1 +CCOC(=O)c1ccc2c(c1)N(C(=O)OCC)CC(=O)N2 +Cc1nn(CC(C)C)c(C)c1CC(=O)N1CCN(C(=O)CO)CC1 +Cc1cc(COC(=O)c2ccc3c(c2)NC(=O)C2CCCN32)no1 +Cc1cccnc1NC(=O)CCc1ccc2c(c1)OCO2 +CN1CCN(C(=O)Nc2ccccc2)c2ccccc21 +Cc1cccnc1CNC(=O)NC(C)(C)c1nc(C)c(C)s1 +CC1CC1C(=O)Nc1ccc(OC2CCCCC2O)cc1 +COc1ccc(CC(=O)N2CCC(=O)Nc3ccccc32)cc1OC +O=C1C(=O)N(CCc2ccccc2)c2ccccc21 +Cc1ccc(Nc2nc(CSc3nnc(C)n3N)cs2)cc1 +Cc1cc(O)cc(=O)n1C1OC(=O)c2ccccc21 +CC(=O)c1cccc(NC(=O)CCc2ccccc2O)c1 +Cc1ccc(C#N)c(-c2cc(NCCO)nc3[nH]ccc23)n1 +CSc1cc(C(=O)NCc2ccc(F)c(C)c2)ccn1 +Cc1cccc(Nc2nc(C(=O)NCCN3CCOCC3)cs2)c1 +Cc1nn(C)c2ncc(NC(=O)NCCC3=CCCCC3)cc12 +CC(C)Sc1ccccc1C(=O)NCCC(=O)N1CCOCC1 +CN(Cc1[nH]nc2c1CCC2)C(=O)c1cnn2ccn(C)c12 +CNS(=O)(=O)c1cc(NC(=O)NCc2ccnn2C)ccc1C +COc1ccc(C(=O)Cc2nc3cc(C)ccc3oc2=O)cc1OC +Cc1nccc(C(=O)Nc2nnc(C(C)C)s2)n1 +CC(C)NC(=O)CN1CCN(C(=O)c2cccc3ccccc23)CC1 +O=C(NCCN1CCOCC1)C1Cc2cc(F)ccc2O1 +CCOc1ccc2[nH]cc(C(=O)NCc3cccnc3)c(=O)c2c1 +Cn1nc2n(c1=O)CCN(C(=O)Nc1ccc3oc(=O)ccc3c1)C2 +N#Cc1cccc(NC(=O)c2nccc3cccc(N)c23)c1 +CCCCOc1cccc(NC(=O)c2cnccn2)c1 +COc1cc(C)ccc1OCc1nnc(-c2ccc(F)cc2)o1 +Cn1ccc2c(NC(=O)c3cccnc3)cccc21 +CNC(=O)C1CCCN(S(=O)(=O)N(C)C2CCCCC2)C1 +Clc1ccc(Cc2noc(NC3CC3)n2)c(Cl)c1 +COc1cccc(CNc2ccccc2C(N)=O)n1 +O=C(Cn1nc(-c2ccccc2F)ccc1=O)NCc1ccncc1 +Cn1ncc2c(-n3nnc(-c4cccc(Cl)c4)n3)ncnc21 +COc1ccc2c(c1)C(NC(C)=O)C(=O)N2CCOc1ccccc1 +CCC1CCC(NC(=O)CSc2nncn2C(C)C)CC1 +CC(C)c1nnc(-c2sccc2NC(=O)c2ccco2)o1 +COc1ccc(F)cc1NC(=O)c1cnn(-c2ccccc2)n1 +NS(=O)(=O)c1cccc(NC(=O)CCc2ccsc2)c1 +Cc1c(C2CC2)n[nH]c1NC(=O)Cn1c(C)cc2ccccc21 +N#Cc1cnn(C(=O)Cc2cc(Cl)c3c(c2)OCCCO3)c1N +CC(C)(C)CCNC(=O)Cn1cc(Cl)c(=O)[nH]c1=O +CCOC(=O)CCC(C)NC(=O)Nc1cc(F)c(F)cc1F +O=C(NC1CCCCNC1=O)c1sccc1-c1ccccc1 +O=C(COc1ccccc1F)NCC1(c2cccs2)CCOCC1 +O=C(CO)N1CCN(C(=O)c2cc3cccc(F)c3o2)CC1 +COc1ccccc1NC(=O)c1c(C)c(N)c[nH]c1=O +CN1CCC2(CCC1=O)CN(C(=O)Cc1cccs1)CCN2C +Cc1nnc(CNc2cc(-c3ccc(F)cc3)nc3ccnn23)o1 +CC(=O)c1cc(-c2cc(F)ccc2F)nn(C)c1=O +COc1nc2c(cc1C(=O)NC1c3ccccc3CC1O)CCC2 +CC(C)(C)CN1CC(NC(=O)C2(C)CCCCC2)CC1=O +CNC(=O)c1cnc(C=Cc2cc(Cl)c(OC)c(OC)c2)s1 +Cc1cc(C(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)c2ccccc2n1 +COC1CCN(S(=O)(=O)N2CCCC2c2ccc(F)cc2)CC1 +COc1cc(NC(=O)C2CCOC2)c(OC)cc1Cl +CC(C)NC(=O)Cc1ccc(NC(=O)c2scc3c2OCO3)cc1 +Cc1ccc(CC(=O)Nc2nnc(Cc3ccccc3)o2)c(C)c1 +CCn1cc(CNc2nnc(Cc3cccc(F)c3)s2)cn1 +CCOC(=O)c1cnc(COc2cccc(C)c2)nc1N +OCCn1c(-c2ccccc2)nc2ccc(F)c(F)c21 +CCN(C)C(=O)c1cc(-c2csc(C)n2)n2ccccc12 +Cc1nnnn1CCc1cc(Cl)c2c(c1)OCCCO2 +Cn1ncc2c(N3C4CCC3CC(O)C4)nc(-c3cccnc3)nc21 +N#CC(NCc1ccncc1)c1cccc(Cl)c1 +Cc1cc(CN2CCN(C(=O)CCc3c(C)nn(C)c3C)CC2)on1 +CCC(=O)N1CCN(C(=O)c2ccc3cnsc3c2)CC1 +O=C(Cn1cnc2ccccc2c1=O)NCc1ccncc1 +Cc1ccc(NC(=O)N2CCN(C(=O)N(C)C)CC2)cc1 +Cc1cccc(C(=O)NC(C)c2cnn(-c3cccc(F)c3)c2C)n1 +Cc1nnnn1-c1cccc(NC(=O)C2CCCN2C(=O)C2CC2)c1 +COc1c(F)ccc2c1C(c1ccncc1Cl)NCC2 +COc1ccc(S(=O)(=O)n2ccnc2)c(C)c1C +COc1cccc(OC)c1OCCn1cnc2ccccc2c1=O +COc1cccc(NS(=O)(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1 +c1cc(CSc2nnc(-c3ccncc3)o2)ccn1 +CC(=O)N(C)c1ccc(NC(=O)NCc2cnn(C)c2C)cc1 +CC(NC(=O)Cc1ccc(F)cc1F)c1ccc2c(c1)OCCO2 +COc1ccc(C(O)C(C)NC(=O)c2ncccc2OC(C)C)cc1 +O=C(NCc1ccccc1OC(F)F)c1ccc(=O)[nH]c1 +c1ccc(Cc2nnc3n2NC(c2ccco2)S3)cc1 +CC(=O)OC1C(OC(C)=O)N(C(C)=O)CN1C(C)=O +CCOCC(=O)NC(c1ccccn1)c1ccccc1OC +CCN1c2ncccc2C(=O)NC12CCN(C(=O)C(C)C)CC2 +Nc1ncc(NC(=O)OCc2ccccc2)cc1Br +Cn1cccc(NC(=O)c2ccc(NC(=O)c3ccccc3)cc2)c1=O +CC(C)S(=O)(=O)N1CCN(c2ncc(Cl)cc2Cl)CC1 +Cn1cccc(NC(=O)C2(c3ccc(F)cc3F)CCOCC2)c1=O +Cc1noc2nc(C(C)C)cc(C(=O)NCC(=O)N3CCCCC3)c12 +O=C(NCc1cccnc1-n1ccnc1)c1ccc(F)cc1 +CCc1ccc(CNC(=O)Nc2nnc(C(F)(F)F)s2)s1 +O=C(NCC1Cc2ccccc2O1)c1cccc(Nc2ncccn2)c1 +O=C(NCCCCOc1ccc(F)cc1)c1ccnnc1 +C=CCN(Cc1ccccc1F)S(=O)(=O)N(C)C(C)C +CCC1Oc2ccccc2N(CC(=O)NCc2ccccn2)C1=O +COc1ccc(NC(=O)NCc2cccnc2)cc1NC(C)=O +COc1ccc(F)cc1C(C)NC(=O)Cn1ccc(C(F)(F)F)n1 +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)NC1CCCCC1 +NC(=O)CCCNC(=O)c1ccc(Br)cc1F +CCOC(=O)c1sc2nc(Cc3nc(C)cs3)[nH]c(=O)c2c1C +CC(OC(=O)Cc1cccs1)C(=O)Nc1ccc(Cl)cn1 +O=C(OCC1CC(=O)N(Cc2ccccc2)C1)c1n[nH]c2c1CCC2 +COc1ccccc1OCC#CCNC(=O)Cc1cccs1 +COC(=O)c1cccc(-c2ccc3c(c2)C(=O)C(=O)N3)c1 +CCc1cc(S(=O)(=O)N2CCCC(=O)C2)ccc1OC +Cc1ccc(F)cc1CC(=O)N(C)Cc1csc(C(C)C)n1 +CN1C(=O)COC(c2ccc(NC(=O)C3CCOCC3)cc2)C1CO +CCOC(=O)c1ccsc1NC(=O)COc1cc(C)ccc1F +Cc1cc(NC(=O)C(c2ccccc2)N(C)CCc2ccccc2)no1 +O=C(CNC(=O)NC1CCc2cc(F)ccc21)Nc1cccnc1 +Cc1nccn1-c1ccc(C(C)NC(=O)c2ccoc2)cc1 +Cn1ccc2ccc(C(=O)N3CCn4c(nnc4C(F)(F)F)C3)cc21 +O=C(NCc1cccs1)C1CC2CCCC(C1)C2=O +O=C(NCc1cc(-c2ccc(F)cc2)on1)c1ccc2[nH]cnc2c1 +CCCc1cc(N)n(-c2ccc(C(F)(F)F)cc2)n1 +COCC(=O)NC(C)c1sc(-c2ccc(C)cc2)nc1C +Cn1c(N)nnc1SCC(=O)N1CCc2ccccc21 +COCCn1cc(NCc2cc(F)ccc2Br)cn1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCc1ccccc1Cl +COc1ccc(Br)cc1C(=O)CC#N +CC(Oc1ccccc1-c1cccc(O)c1)C(N)=O +N#Cc1cc(S(=O)(=O)Oc2ccc(F)cc2F)ccc1F +COc1ccc(C(=O)NC(C#N)c2cccc(OC)c2)cc1 +CCOCCOC1CCN(C(=O)c2cn(C)nc2C(C)(C)C)C1 +O=C(NCc1cccc(Br)c1)c1n[nH]c2c1CCCC2 +Cc1nnc2ccc(C(=O)N3CCN(CC(C)(C)O)CC3)cn12 +Cc1nnc(CN(c2nccs2)S(=O)(=O)c2ccccc2)o1 +COc1cccc(NC(=O)c2ccc(F)cc2F)c1 +Cc1cc2ncn(CC(O)CN3CCn4c(C)nnc4C3)c2cc1C +CC(=O)c1ccc(NC(=O)COC(=O)c2cc3c(s2)CCC3)cc1 +CN1CCC(C(=O)NCCc2cccnc2)CC1=O +CC(=O)Nc1ccc2c(c1)C(=O)c1cc(NC(C)=O)ccc1-2 +O=C1CC(C2CCCCN2C(=O)Nc2ccc3c(c2)COC3)CN1 +COCCNc1nc2c(OC)cc(Cl)c(OC)c2s1 +CN(C)C(=O)c1ccc(CNc2ccc(F)cc2F)[nH]1 +COc1ccccc1NC(=O)C1CCN(C(=O)NC2CC2)CC1 +CC(=O)NCCNc1ncnc2sc3c(c12)CCC(C)C3 +Cc1ccsc1CN(C)C(=O)c1cccc(N2CCCNC2=O)c1 +N#Cc1c(-c2c[nH]nc2-c2ccc(F)cc2)cc(C2CC2)nc1N +NC(=O)C1CCCN(C(=O)CN2CCc3ccc(Cl)cc3C2)C1 +Cc1ccc2c(c1)c(CO)cn2Cc1c(C)noc1C +O=C1Nc2cc(SC3CCOCC3)ccc2C1=O +Cc1cccc(C(C#N)NC(=O)c2ccccc2F)c1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)N1CCCC(CO)C1 +CC(=O)Nc1ccc(C(=O)NCCc2nnc3ccccn23)cc1 +COc1ccc2c(CC(=O)NC(C)c3cccnc3)coc2c1 +C=CCn1c(SCc2nc3ccccc3s2)nnc1C1CC1 +Cc1cccc(NC(=O)CCSc2ccc(Cl)cc2)n1 +Cc1ccc2ncc(C(=O)N3CCCC3c3cccc(N(C)C)c3)n2c1 +O=C(c1cnc(C2CC2)s1)N1CCCC(n2cccn2)C1 +NC(=O)c1ccc(NC(=O)CSc2nncs2)cc1Cl +O=C(CCNC(=O)NC1CCCc2occc21)NC1CCCC1 +CCCc1noc2ncc(C(=O)NCC3(C(N)=O)CCOCC3)cc12 +CCNc1nnc(SCC(=O)c2ccc(F)c(F)c2)s1 +Cc1cccc(NC(=O)CCNC(=O)C(C)Sc2ccccn2)n1 +Cc1ccc(C2C(C(N)=O)=C(N)Oc3[nH]nc(C)c32)s1 +CS(=O)(=O)Nc1ccccc1NC(=O)c1ccc(C(N)=O)cc1 +Cn1cc(CC2CCN(C(=O)Nc3ccc4c(c3)COC4)C2)cn1 +NC(=O)C1CCCN1C(=O)CCCOc1ccccc1 +CC(C)CCn1c(=O)c2cccnc2n(Cc2ccccc2F)c1=O +c1coc(-c2nc(N3CCCC3)c3ccccc3n2)c1 +COc1ccc2c(ccn2CCC(=O)NCc2ccncc2)c1 +CCCNC(=O)C(C)OC(=O)c1cc(C(C)=O)cn1C +COc1ccc(CNC(=O)c2ccc(N3CCOCC3)nc2)cc1 +Nc1ccc2nc(-c3cc(Cl)ccc3F)oc2c1 +Cc1ccc(C)c(N(C)Cc2sc(C)nc2C)c1 +O=C(c1cccc(-n2cccn2)c1)N1CCOc2ccc(F)cc21 +O=C(CCc1ccco1)Nc1ccc(SCc2cccnc2)cc1 +CC(C#N)CCC(=O)Nc1ccc(Cl)cc1Cl +COc1cc(NC(C)=O)c(C(=O)OCc2cc(C)on2)cc1OC +CC(C(=O)OCCCNC(N)=O)N1CCc2ccccc2C1 +Cc1ccc(OCc2nc(C)c(CC#N)s2)cc1 +Cc1ccc2[nH]c3c(NCc4ccco4)ncnc3c2c1 +CC1CCN(C(=O)C2CCc3ccccc3N2)CC1 +COc1ccc(F)cc1-c1cc(C(C)=O)c(C2CC2)o1 +Cc1noc(CNc2ccccc2C(=O)N(C)C2CCCCC2)n1 +Cc1nc(-c2cccs2)sc1CNC(=O)Cn1cccc1 +COc1cccc(C(=O)OCC(=O)Nc2cc(F)ccc2F)c1 +CCCNC(=O)Cn1cnc2sc(-c3ccccc3)c(C)c2c1=O +COCCN1C(=O)CCC12CCC(NC(=O)c1cnc(C)cn1)CC2 +C=CCNC(=O)CCC(=O)c1cccc(Br)c1 +O=C(NCc1noc(C2CCCC2)n1)c1coc(-c2ccccc2)n1 +CC1(C)COCCN1Cc1cc(=O)n2ccsc2n1 +CCN1C(=O)C(C)(C(=O)Nc2ccncc2)Sc2ccccc21 +Cc1nnc2c(=O)n(CC(=O)NCC(C)C)c3cccnc3n12 +CCOc1ccccc1C(=O)NC(C)C(O)c1ccc(OC)cc1 +C#Cc1cccc(NC(=O)NCCNC(=O)C2CC2)c1 +Cc1cc(=O)c(OCC(=O)N=c2[nH]cc[nH]2)cn1C +CCc1nnsc1C(=O)N1CC=C(c2ccccc2)CC1 +Cc1c(N)cc(C(=O)N2CCN(C)CC2)cc1F +COCCOC(=O)C1=C(C)NC(=O)NC1c1ccc(C(C)(C)C)cc1 +CCCCNC(=O)NC(C)COc1ccc(F)cc1 +COC(=O)C1(NCc2coc(-c3ccc(F)c(F)c3)n2)CCC1 +O=C(NC1CCCC1)C1CCC(Cn2cnnn2)CC1 +CCSc1ccc(-c2cccc(NC(=O)COC)c2)nn1 +Cc1cc(C)n2nc(C(=O)NC(C)Cc3cccs3)nc2n1 +CNC(=O)C1CCCN1Cc1nc2sc(C)c(C)c2c(=O)[nH]1 +CCC(C)NC(=O)Cn1nc2c(N3CCCCCC3)nccn2c1=O +CC(C)n1ccnc1-c1nccn1C(C)Cn1cncn1 +CCOC(=O)C(C)(NCC(F)(F)F)c1ccc(F)cc1 +Cc1cccc(C(C)C)c1NCC(=O)c1ccc2c(c1)OCO2 +COC(=O)c1cc(C)ccc1OC(=O)C1CCN(C(=O)N(C)C)CC1 +CC(=O)N(C)c1ccc(NC(=O)CN(C)c2ccccc2)cc1 +c1csc(-c2csc(Cc3nnc4n3CCCCC4)n2)c1 +O=S(=O)(CC1CCOC1)c1nnc2ccccn12 +CN(C(=O)c1c(Cl)c2ccccc2n1C)C1(C#N)CCC1 +CCCc1cnc(N2CCN(CC(=O)OCC)CC2)nc1 +N#Cc1cc2c(nc1NCCCCn1ccccc1=O)CCCC2 +COC(=O)N1CCC(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)CC1 +O=C(NCC1(O)CCCc2ccccc21)c1ccc2[nH]nnc2c1 +O=C(COc1ccccc1)N1CCN(c2cccc3cnccc23)CC1 +Cc1ccc(C(=O)N(C)Cc2cn[nH]c2)cc1Br +COc1ccc(-c2ncc(S(C)(=O)=O)c(N)n2)cc1 +O=C(NCCC(=O)N1CCOCC1C1CC1)C1CCCCC1 +Cc1ccc2nc(CNC(=O)c3ccc(=O)[nH]c3)cn2c1 +CCCC(C)C(=O)Nc1cccc(NC(C)=O)c1C +COc1ccc(F)cc1S(=O)(=O)Nc1ccccc1SC +CC(C(=O)Nc1cccnc1)n1nnc2ccccc2c1=O +O=S1(=O)CCCN1Cc1nnc(-c2ccccc2F)o1 +O=C(Nc1ccccc1O)c1scnc1C1CC1 +CC(=O)c1c[nH]c(C(=O)Nc2ccccc2N2CCCCC2)c1 +Nc1ccc(F)c2c(C(=O)N3CCOCC3)nccc12 +Cc1ccc(C(=O)Nc2ccc(C)c(S(=O)(=O)N(C)C)c2)s1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2ccc3c(c2)CCC3)cc1 +COCc1ccccc1C(=O)Nc1ccc(OC)cc1OC +O=C(OC1CCOCC1)c1cccc(F)c1Cl +Cc1cc(Cl)ccc1NCCn1cnc2c1c(=O)n(C)c(=O)n2C +CCCC(C)NC(=O)C1CCCN(C(=O)c2cccnc2OC)C1 +O=C(NC1C(O)C(O)CC1C1CCCCC1)c1cccnc1 +COc1ccc(NC(=O)Cc2nc(CO)cs2)c(OC)c1 +CCSc1ccc(C)cc1-c1cc(C(=O)OC)n(C)n1 +CC(NC(=O)Nc1ccncc1F)c1ccc(-n2cccn2)cc1 +Cc1n[nH]c(NC(=O)c2ccccc2Br)c1C +NC(=O)C1CCN(C(=O)NCc2ccnc(-n3cccn3)c2)C1 +CC(C)N(C(=O)Cn1nc2ccccn2c1=O)C1CCOCC1 +Cc1c(C)n(CC(C)C)c2ncnc(NCc3ccncc3)c12 +CCc1cc(C(=O)NCc2cc(Br)ccc2F)[nH]n1 +Cc1cc(C)nc(Nc2nc(CC(=O)Nc3ccon3)cs2)n1 +CC(O)CN(C)C(=O)c1cc(C#CCO)ccc1F +COc1cc(COC(=O)Cn2ccc(=O)c3ccccc32)ccc1C +Cc1ccc(CN2CCC(=O)N(Cc3ccccc3C)CC2)s1 +Cc1cccc2c(=O)n(CC(=O)Nc3ccncc3)cnc12 +Cc1cc(C(=O)Nc2ccc3c(c2)CCC3)c2c(C)nn(C)c2n1 +CCCn1c(-c2ccc[nH]c2=O)nc2ccccc21 +O=C(CNc1ccccc1C(F)(F)F)NCC1CC1 +CC(C)n1ncc2c(C(=O)NCc3cccnc3)c3c(nc21)CCC3 +N#Cc1nnn(-c2nccs2)c1Cc1ccccc1 +CN(Cc1ccccn1)C(=O)Nc1cc(C(F)(F)F)ccc1F +N#Cc1cccc(Cl)c1NCCc1ccc(S(N)(=O)=O)cc1 +NC(=O)C(NC(=O)C1CC1c1ccco1)c1ccccc1 +N#Cc1cccc(CNC(=O)NCC2(Sc3ccccc3)CC2)c1 +CC(C)(O)c1cnc(CCOc2ccccc2Cl)s1 +C#CCC(NC(=O)c1ccc(-c2ccc(C)o2)s1)C(N)=O +O=C(Cc1c(F)cccc1Cl)N1CCCCC1 +Cc1ccc(-c2nnc(C3CCN(Cc4cccnc4)C3)o2)cc1 +Cc1cnn(CCC(=O)NC(C)C(=O)NC(C)(C)C)c1 +O=C(NC1C(c2cccnc2)CC(O)C1O)C1CCC1 +COc1cc(F)c(S(=O)(=O)N2CCCCC2C)cc1OC +COc1ccc(Nc2nccnc2C#N)cc1OC +COc1cccc(Oc2ccc(NC(=O)NCCO)cc2)c1 +CC(C)c1nc(CC(=O)Nc2ccc3c(c2)COC3)cs1 +CC(Nc1cccc(CO)c1)C(=O)N1c2ccccc2CC1C +COc1ccccc1C(O)CNCc1ccccc1 +CC(C)NC(=O)c1ccccc1NC(=O)CNc1cccc(F)c1F +Cc1ccn(-c2cccc(NC(=O)c3cc4c([nH]c3=O)CCCC4)c2)n1 +CN(Cc1cnn(C)c1)C(=O)NCc1ccc(F)c(Cl)c1 +COc1ccc2c(CC(=O)Nc3ccc(OC)nc3)cc(=O)oc2c1 +CSc1ccc(CNC(=O)Cn2cncn2)cc1 +CC(=O)c1ccc(NCC(=O)c2cccc(N)c2)cc1 +Cc1ccc(C)n1C(C)C(=O)N1CCC(Nc2cccnn2)CC1 +Cc1nc(-c2nnc(NC(=O)c3ccc(F)c(F)c3)o2)cs1 +Cc1nnc2n1N=C(c1ccc3c(c1)CCCC3)CS2 +CC(C)COCCCNC(=O)N1CCOCC1C1CC1 +CCOC(=O)c1sc(-c2ccc(C)o2)cc1N +CCn1ccc(C(=O)Nc2cc(OC)ccc2OC)n1 +CC(O)Cc1nsc(NC(=O)c2cccs2)n1 +O=C(CN1CCc2cc(F)ccc2C1)NCc1ccccn1 +N#CCOc1cccc(CC(=O)N2CCCC(N3CCCC3=O)C2)c1 +COc1cc(C)c(NC(=O)Cc2ccsc2)cc1OC +COC(=O)CNC(=O)CNC(=O)NCc1ccc(Cl)cc1 +COc1ccc(NC(=O)NCc2ccccc2)c(OC)c1 +O=C(C1CC(=O)N(C2CCCC2)C1)N1CC(Oc2ccccc2F)C1 +Cc1ccsc1CNC(=O)C1NCCc2ccccc21 +Cc1nc(COCC23COCC2CN(C(=O)c2cnoc2)C3)cs1 +Cc1ccc(C(C)NC(=O)Nc2cnc3c(c2)c(C)nn3C)cc1 +CCOc1ccc(NC(=O)c2cc3ccccc3[nH]2)cc1OC +COCC1(O)CCN(C(=O)c2ccc(O)c(C)c2)CC1(C)C +COc1ccc(C(=O)CSc2nncn2C)cc1Br +CN(C)C(=O)C1CCC2(CCN(Cc3nccs3)CC2)O1 +CNc1cnc(CC2COCCN(C(=O)c3ccccc3)C2)cn1 +COc1c(Cl)cccc1NC(=O)c1ccc(-n2cncn2)nc1 +COc1ccc(C2CN(C(=O)OC(C)(C)C)CCN2)cc1OC +Cc1ccc(NC(=O)CNC(=O)c2cccc(C)c2)cc1 +Cc1ccc(-c2nc(-c3ccc(C#N)cn3)no2)s1 +Nc1cc(NC(=O)CCOCC2CC2)ccc1Cl +CC(NC(=O)CNC(=O)c1ccccc1F)c1ccccc1 +COC(=O)c1c(F)cc(Br)cc1Br +CC(C)c1nnc2n1CCN(CC(=O)NCCOc1ccccc1)C2 +CC1(C)NS(=O)(=O)N(c2ccc(S(N)(=O)=O)cc2)C1=O +CC(C(=O)N(C)c1ccc(Br)cc1Cl)n1cncn1 +CCN(Cc1ccoc1)C(=O)Nc1ccc(C)c(C(=O)NC(C)C)c1 +O=C(NCc1nncn1C1CC1)c1cccc(-c2ccoc2)c1 +Cn1c(=O)oc2ccc(NC(=O)c3ccccc3Cl)cc21 +Cc1noc(CNC(=O)NCc2ccc(F)cc2)n1 +O=C1CC(C(=O)N2CCc3ccccc32)CN1Cc1ccco1 +COc1cc2ncnc(N3CCOCC3)c2cc1OC +CC(Cn1ccnc1)NC(=O)c1ccc(Cn2cccn2)cc1 +CC(C)(C)C(=O)N1CCC2CC(=O)N(c3ccccc3)CCC2C1 +Nc1occc1C(=O)c1cncc(Br)c1 +CC(C)CCNC(=O)CCC(=O)c1ccc(N)cc1 +Cc1cc(=O)c(OCC(=O)N2CCOC(c3ccccc3)C2)co1 +C=CCNC(=O)CCC(O)c1cc(C)c(C)cc1OC +OC1(CNc2cc(-c3ccncc3)nc3ccnn23)CCCCC1 +COCC(=O)N1CCC(C(=O)N(C)C(C)C)CC1 +CCCOc1c(OC)ccc2c1C(c1cc[nH]c1)NCC2 +CC(CCC(C)(C)C)NC(=O)N1CCOC(C(N)=O)C1 +Cc1cc(C)nc(C(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)c1 +Cc1ccc(C)c(NC(=O)CN(C)C(=O)c2ccccc2)c1 +O=C1CCC(NC(=O)c2cc3c(s2)CCCC3)CC1 +CCCCN1CCN(C(=O)c2cn3c(n2)CN(CC)CC3)CC1 +CC(O)C1CCN(C(=O)Nc2ccc3c(c2)OC(F)(F)O3)CC1 +COCc1ccc(CNC(=O)c2ccc(-c3ccccc3)[nH]c2=O)cc1 +O=C(Cc1noc2ccccc12)Nc1onc2c1CCCC2 +Cc1ccccc1NC(=O)CNc1ccn(-c2ncccc2Cl)n1 +CCn1c(N)nc2cc(C(=O)NC3Cc4ccccc4C3)cnc21 +CCC(CC)N(C)C(=O)CCN1C(=O)COc2ccccc21 +CC(C)COC(=O)CSc1nc2ccccc2n1C +CCOc1ccc(-c2nc(C3CCOC3)no2)cc1 +CCOc1ccc(C(=O)CCC(=O)N2CCCC(O)C2)cc1 +CCCCn1c(N)c(N(CC)Cc2cccc(C#N)c2)c(=O)[nH]c1=O +COc1ccc(C(=O)Oc2cccc(C(F)(F)F)c2)nn1 +O=C(NCCCN1CCOCC1)c1cc(-c2ccccc2O)no1 +CN(Cc1ccccc1)c1cc(C(F)(F)F)cnc1N +CCOc1ccc(Cl)cc1S(=O)(=O)NCCN1CCOCC1 +Cc1cccc(OCC(O)Cn2cnc3ccccc32)c1C +CCN(CC)C(=O)c1c(C)nc(N)nc1COc1ccc(C)cc1 +O=C(CN1CCN(C(=O)c2ccco2)CC1)Nc1ccccc1Cl +O=C1NCCN1Cc1ccccc1NCCc1ccccc1 +COCc1cccc(C(=O)N2CC=C(c3ccccc3)CC2)c1 +Cc1nnc(NCCCC(=O)N2CCc3ccccc3C2)c(C#N)c1C +CN(C(=O)c1cc2c(nc1N)CCC2)C1CCCCC1 +CC(C)CCNC(=O)NC1CCOc2c(Cl)cccc21 +Cn1cncc1C1NCCc2c(Cl)cc(F)cc21 +CCNC(=O)c1ccc(NC(=O)Cc2cccc(F)c2F)cc1 +Cc1ccc(CN2CC(C(=O)NCC(N)=O)CC2=O)cc1 +CCN(Cc1ccccc1)C(=O)C(C)Sc1n[nH]c(N)n1 +CCc1[nH]c(C(=O)Nc2ccc(SC)cc2)c(C)c1C(=O)OC +CCCCN(CC)C(=O)CCC(=O)N1CCCn2nc(C)cc21 +CCCC(=O)NCC(=O)N(C)Cc1nccn1C(F)F +O=C(NCC1(c2cccc(C(F)(F)F)c2)CCOCC1)C1CCC1 +CN(C)c1ncccc1N(C)C(=O)Cc1cc(F)ccc1F +CC1CCCCN1C(=O)CNc1ccn(-c2ncccc2Cl)n1 +Cc1ccc(OC(C)C(=O)NCC(O)c2c(F)cccc2F)cc1 +NC(=O)NCC(=O)NCC(=O)OCc1ccccc1 +Cn1cc(C(=O)N2CCC(Cc3ccc(CO)cc3)C2)c(=O)[nH]c1=O +Cc1ccc(-n2nc(C(=O)N3CCCC3)cc2N)cc1 +Cc1ccc(C(=O)COC(=O)COc2ccccc2)cc1 +CC(=O)N1CCCc2ccc(-c3nc4n(c3CO)CCS4)cc21 +Cc1noc(C)c1CSc1nnc(-c2cccs2)n1C1CC1 +CCCN1C(=O)CCC2CN(C(=O)c3nnc4n3CCCC4)CCC21 +Cc1ccc(NCC=Cc2ccc(C#N)cc2)cc1C(N)=O +COc1ccc(C2CCc3nc(N)nn3C2C)cc1 +Nc1ncc(-c2nc3ccccc3o2)c(-c2ccncc2)n1 +CCNC(=O)CN(C)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +CCCn1nnnc1COc1ccc(S(C)(=O)=O)cc1 +CC(=O)c1cccc(OCC(=O)NC(C)c2c(C)noc2C)c1 +CC(Oc1ccc(F)cc1)C(=O)NCc1cccnc1 +CCC(C)(C)NC(=O)CS(=O)(=O)c1ncccc1Br +O=C(NCCOc1ccc(Cl)cc1)c1n[nH]c(=O)c2ccccc12 +CCOc1cc(NC(=O)c2csnn2)ccc1OC +CCc1onc(C)c1NC(=O)N(CCO)C1CCCc2ccccc21 +COC(=O)c1cc(-c2c(OC)ccc3ccccc23)nn1C +Cc1csc(NC(=O)C2CCCN(C(=O)NC3CC3)C2)n1 +COc1ccc(C(C)NC(=O)NCCC(=O)N2CCCC2)cc1F +CCC(c1nc(-c2ccc3nc[nH]c3c2)no1)n1cccn1 +O=C(NC1CC1)c1cc2occc2n1Cc1ccc(Cl)cc1 +COc1ccc2c(c1)CN(S(=O)(=O)N1CCOCC1)CC2 +COc1cc2nc(CN(C)c3ccccc3)[nH]c(=O)c2cc1OC +O=C(Cn1nc2c(cc1=O)CCCCC2)Nc1nnc(C2CC2)s1 +c1ccc(CCNCc2c[nH]nc2-c2cccs2)nc1 +COc1cccc(-c2c(C)sc(C#N)c2NC(C)=O)c1 +CN(C)C(=O)c1cccc(S(=O)(=O)NCc2ccccc2)c1 +CCC(CC)NC(=O)c1ccc2c(c1)OCC(=O)N2 +CC(NC(=O)c1ccco1)C(=O)NC(C1CC1)C1CC1 +Cc1noc(C)c1CSc1ccccc1C(=O)Nc1nccs1 +O=C(c1ccnc(OC2CCC2)c1)N1CCOC(c2cccs2)C1 +Nc1cccc(-c2nnc(N3CCc4ccccc4C3)o2)c1 +CCc1ccccc1OC(=O)CCn1cnc2ccccc2c1=O +Cc1ccsc1CNC(=O)CCNC(=O)OC(C)(C)C +Cc1ccc(NC(=O)c2ccsc2)cc1N1CCCCC1=O +CC(Nc1ncnc2c1cnn2C)C(=O)N1CCCCC1 +COc1ccc(NC(=O)N(C)C(C)c2ccccc2OC)cc1OC +CS(=O)(=O)c1nsc(C(=O)NC2CCCC2)c1N +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)OCC1(C)COC1 +COc1ccc(OC(C)C(=O)NCc2cccnc2)cc1 +COC(=O)c1ccc(CSc2nncn2-c2ccccc2)cc1 +CCC(OC)C(=O)NCCc1nc2ccccc2[nH]1 +Cc1ccc2oc(SCC(=O)Nc3cccc(F)c3)nc2n1 +Cc1cccc(CS(=O)(=O)Nc2ccc(C)nc2)c1 +O=C(Nc1ccc(Cl)c(F)c1)c1ccc(N2CCCC2)nn1 +O=C(C1NCc2ccccc21)N1CC2C3CCC(C3)C2C1 +CCc1nnc(-c2cc(S(=O)(=O)NCc3ccccc3C)c[nH]2)o1 +CCNC(=O)CSc1cc(C)c(C#N)c2nc3ccccc3n12 +COc1ccc(NCc2ccc(OC(F)(F)F)cc2)cn1 +COc1ccc(C(=O)c2ccc(NC(C)=O)cc2)cc1F +Nc1ccc(Nc2nc3ccccc3s2)c(O)c1 +COc1c(Cl)cc(C(=O)N(C)CCOCC2CC2)cc1Cl +Cc1ccc(NC2CCCc3c2cnn3C)c(F)c1 +O=C(OCCc1c[nH]nc1C(F)(F)F)C1COCCO1 +CN(C)c1nc2cc(NC(=O)Nc3ccccn3)ccc2o1 +CNC(=O)c1c(C)cccc1NC(=O)c1ccc(F)c(OC)c1 +COc1ccc(-c2ccc(=O)n(CC(=O)N3CCCCCC3)n2)cc1 +COc1cc(N)ccc1NC(=O)c1ccc2ccccc2c1 +O=C(NCCS(=O)c1ccccc1)c1ccccc1-n1cnnn1 +Cn1cc(-c2nc3scc(-c4ccc(F)cc4)c3c(=O)[nH]2)cn1 +NC(=O)C1CCN(C(=O)c2ccc(C3CCCCC3)cc2)C1 +COC(=O)CCCn1nc(NC(=O)c2ccc3c(c2)OCO3)cc1C +CN1CCOc2cc(C(=O)c3ccccc3F)ccc21 +Cn1nnc2c(NCCn3ccc4ccccc43)ncnc21 +Cc1cccc(-c2noc(CCC(=O)NC(C)C)n2)c1 +COc1nn(C)cc1C(=O)N1CC(c2nc(-c3ccncc3)no2)C1 +CCCOCC1CCN(C(=O)Cn2sc3ccccc3c2=O)C1 +CSc1ncc(C(=O)N2CCNC(=O)C2)n1-c1ccccc1 +O=C1c2ccccc2C2(c3ccccc3)N1CCN2C(=O)C1CC1 +Cc1ccc(C(=O)N2CC(NS(C)(=O)=O)C(C(C)C)C2)cc1O +COC(=O)Nc1ccccc1C(=O)N(C)Cc1ccc(F)cc1F +COc1ccccc1CNC(=O)Nc1ccc(NC(C)=O)c(Cl)c1 +O=C(NCC1CN2CCCCC2CO1)Nc1ccc(F)cc1 +CN(CC(F)(F)F)C(=O)CNC(=O)c1ccc(C(C)(C)C)cc1 +COCCNC(=O)NCc1ccccc1COC +Cc1cc(OCC(=O)Nc2ccc(N)cc2C)ccc1Cl +CN(C(=O)CCc1cccs1)C1CCN(c2ccccc2)C1=O +Cc1ccc(C(=O)N2CC(c3nc(C)no3)C2)cc1 +CCCCN(C(=O)c1ccc(=O)n(C)n1)C(C)CC +Cc1ccc(OCC(=O)C(C#N)c2nc3ccccc3[nH]2)cc1C +COCC(C)NC(=O)CNc1cccc2ccccc12 +Cc1cccc(NC(=O)Cn2nc(C)c3c(C)onc3c2=O)c1C +CC(=O)c1cc(-c2ccc(C(F)(F)F)cc2)no1 +Cc1cc(N2CCOCC(Cc3cccnn3)C2)ncn1 +Fc1cc(Cl)c2c(c1)C(c1cnccc1Cl)NCC2 +O=C(NCc1cccc(Cn2cccn2)c1)N1CCOCC1 +Cc1sc(C(=O)NC(C)c2cnn(C)c2)cc1-c1ccc(F)cc1 +CC(C)Cc1ccc(C(=O)Nc2ccn(C)n2)cc1 +CN(CCC(=O)OC(C)(C)C)Cc1cnnn1C +O=C(c1ccc(C(=O)N2CCOCC2C2CC2)cc1)c1cc[nH]c1 +O=C(OCc1cccc(C(F)(F)F)c1)c1ccccc1-n1cnnn1 +CN(C)c1cc(N)c(Br)c2ccccc12 +O=c1ccc2cc(S(=O)(=O)NCCO)ccc2o1 +Cc1nc(NCCCO)c(C#N)c2c1COC(C)(C)C2 +O=C(Cn1c(=O)oc2cc(Cl)ccc21)c1ccccc1 +COc1ccc(CN(C)C(=O)c2ccn(C)c(=O)c2)cc1F +O=C(Nc1cc2c(=O)[nH]ccc2oc1=O)c1ccccc1 +CCOC(=O)Cc1cnc(NS(=O)(=O)c2ccc(C)cc2)s1 +CCCCN(C)C(=O)NCc1ccc(COC)cc1 +CCOc1cc(CNC(=O)c2ccc(C)cc2)ccc1OC +Cc1nc(C)n(Cc2nc(C(C)(C)C)cs2)n1 +CCN(Cc1cccc(NC(=O)NCCc2cccs2)c1)C(C)=O +Cc1cnc(NC(=O)c2oc3ccccc3c2C)s1 +COc1ccc(Cl)cc1CC(C#N)C(=O)N1CCCC1 +COC(=O)C(C)NC(=O)c1ccc(-n2cnnn2)cc1 +Cc1cc(C)c(NCC(=O)Nc2cccc(C#N)c2)c(C)c1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccsc2)CC1 +O=C(Nc1ccc(NC(=O)N2CCCCCC2)cc1)C1CC1 +CCCNC(=O)CNC(=O)c1c(F)cccc1F +Fc1ccc(NCc2cc(Cl)ccc2F)nc1 +CCOc1cc(C(=O)N(C)Cc2cccs2)nn1-c1ccccc1 +CCn1nc(C(=O)OCCn2nc(C)cc2C)c2ccccc2c1=O +Cc1cc(C)cc(-c2ccc(C(=O)NC(C)CO)o2)c1 +CCC(C)C(C)NC(=O)N1CCN(C(=O)c2ccco2)CC1 +CCCC(C#N)C(=O)N1CCC(CC)(CC)CC1 +CCOc1ccc(CNC(=O)c2cc3occc3n2C)cc1 +CN(CC(=O)NCc1cccc(OC(F)F)c1)c1ccc(C#N)cn1 +Cc1ccc(CN2CCCC(c3cncc(-n4ccnc4)n3)C2)s1 +Cn1c(=O)c2c(C(=O)NCc3ccco3)cc(=O)n(C)c2n(C)c1=O +COc1ccc(CNCc2ncc(-c3cccs3)s2)cc1OC +O=C(Nc1ncc(C#CCO)s1)c1cccnc1 +CC(C)CCc1noc(CSc2ccccn2)n1 +COCc1nn(Cc2nn(-c3ccccc3)c3c2CCC3)c(=O)o1 +N#Cc1ccccc1S(=O)(=O)Oc1cccc2cccnc12 +COCCCCNC(=O)c1c[nH]cc1-c1ccccc1 +COc1cc(C(=O)OC(C)C(=O)c2ccc(F)cc2)cc(OC)c1O +N#Cc1nnn(-c2ccccc2F)c1C1CCCO1 +CNC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2c(c1)OCCO2 +COc1cc2c(cc1OC)CN(C(=O)CC1CCCO1)CC2 +COC(C)C(=O)N1c2ccccc2CCC1C(=O)N1CCN(C)CC1 +Cc1ccc(OCCC(=O)NC2CCCc3ccccc32)cc1 +CC1CCc2c(sc(NC(=O)CC#N)c2C#N)C1 +Cc1nc(SCCCC#N)c(C#N)cc1C(=O)Nc1ccccc1 +CCOC(=O)c1ccc(NC(=O)c2ocnc2C)cc1 +CC(=O)NCc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1 +NC(=O)c1cccc(NC(=O)c2cc3ccccc3s2)n1 +CC1Oc2ccc(-c3c[nH]c(N)c3C#N)cc2N(C)C1=O +CC1CCN(c2ncnc3c2nnn3Cc2ccccc2)CC1 +Cc1ccc(-c2nsc(C(=O)NC(C)(C)C)c2N)cc1 +O=C(CCC(F)(F)F)NCCc1c(F)cccc1Cl +Cn1nc(CNC(=O)C2CCC2)cc1-c1ccccn1 +FC(F)(F)C1Cc2ccc(Br)cc2CN1 +NC(=O)c1ccc(-c2nc3ccccc3o2)cc1Cl +CC(OCc1ccccc1)C(=O)NCCN1CCc2ccccc2C1 +CCCCN(C(=O)Cn1cc(Br)ccc1=O)C(C)CC +COc1ccc(C(=O)N2CCCC2)cc1NC(=O)NC1CCCCC1 +Cc1cc(C)cc(C(=O)NC(C)c2ccc(C)o2)c1 +Cn1cnnc1SCc1nc(-c2cccc(Cl)c2)no1 +Cc1nc2cc(Cl)ccc2n1CCCN1CCOCC1 +COCCOC(=O)c1cc(Cl)c(OC)c(OC)c1 +Cc1c(Br)cc2c(c1C)OC(C)CC(=O)N2C +O=C(Nc1cccc(CO)c1)C12CC3CC(CC(C3)C1)C2 +Cc1ccc(C(C)OC(=O)Cc2csc(C)n2)cc1 +CCC(C)C(C(=O)NCc1nc[nH]n1)c1ccccc1 +COc1cccn(CC(=O)N2CCCOC(Cn3cccn3)C2)c1=O +C=C(C)CN(CC)C(=O)CS(=O)(=O)c1ccc(F)cc1 +Cc1cc(C)c2sc(NC(=O)c3ccc4c(c3)OCO4)nc2n1 +Cc1cc(NC(=O)CSc2ccc(-n3ccnc3)nn2)no1 +CNc1cc(C(=O)Nc2ccc(Br)cc2)ccn1 +Cc1cc2c(cc1C)N(CC(=O)N1CCCC1)C(=O)C(C)N2 +CC(NC(=O)C1CCOCC1)c1ccc(F)cc1 +CNC(=O)CNC(=O)c1ccc(C(=O)OC)s1 +CC1CCC(NC(=O)c2scnc2C2CC2)CC1 +Cc1sc2ncnc(OCC(=O)N3CCc4ccccc43)c2c1C +O=C(NC1CCCC(C(F)(F)F)C1)c1ccc[nH]1 +Cc1cnc2n(c1=O)CC(C(=O)N(CC(C)C)CC(C)C)CS2 +CCNc1nc(-c2ccc(C(C)C)n(C(C)C)c2=O)cs1 +COCC(O)CN(C)C(=O)c1ccc(CO)cc1 +CC(C(=O)NCc1ccc2c(c1)OCCO2)n1cccn1 +Cc1cc(CNC(=O)c2ccc(OC(F)F)cc2)no1 +CCCc1cc(=O)n(CC(=O)NCc2ccc(C)cc2)cn1 +CC(C)CC(=O)C1CCCN(C(=O)OC(C)(C)C)C1 +CCCCNC(=O)N1CCC(NS(=O)(=O)CCC)CC1 +Cc1cc(C(=O)N2CCCC(C(=O)N3CCOCC3)C2)c(C)s1 +CCc1ccc2c(c1)C(=O)CC2C(=O)N1CCN(C)CC1 +CCc1ccccc1NC(=O)Cn1c(CC)nc2ccccc2c1=O +CCOC(=O)C1=C(CN(C)Cc2ccco2)NC(=O)NC1 +C=CCNC(=O)Cc1sc(C)nc1-c1cccs1 +Cc1nccn1-c1ccc(NC(=O)Nc2cccc(Cl)c2)cn1 +Cc1ccc(NC(=O)CNc2ccc(C(N)=O)cc2)cc1C +Cc1ccc(C(C)NC(=O)N2CCCCC2CNS(C)(=O)=O)o1 +O=C(Nc1ccc2cn[nH]c2c1)c1cc(F)ccc1Br +CCOCC1CC2(CCN(C(=O)C3CC=CC3)CC2)CO1 +O=C(NCC(O)COCc1ccccc1)c1cc2cccc(F)c2o1 +COCC(Nc1ncc(Br)cn1)c1ccc(C)o1 +CCOC(=O)Cc1nc(N)ncc1C(=O)OCC +CN(C)c1cccc(C(=O)OCC(=O)Nc2cc(F)cc(F)c2)c1 +Cc1noc(C)c1CC(=O)N(C)c1cccc2ncccc12 +Cc1ccccc1C(O)CNC(=O)NCCC(=O)NC1CCCC1 +COCc1cccc(NC(=O)Cn2cnc3ccc(F)cc3c2=O)c1 +O=C(CCn1ccccc1=O)Nc1cccc(Cl)c1-n1cncn1 +COc1ccnc(NC(=O)c2nnn(-c3ccc(C)cc3)c2C)c1 +Cc1oc(-c2ccccc2)nc1C(=O)OCc1cccnc1 +CCCS(=O)(=O)N1CCCC1c1ccc(C)c(C)c1 +COc1cccc(-c2cc(CN(C(C)=O)C(C)C)no2)c1 +CN(CC(F)F)C1CCN(c2cnn(C)c2)C1=O +Nc1cccc2c1nc(C(Cl)(Cl)Cl)n2CCO +N#Cc1ccc(NC(=O)COC(=O)c2ccccc2N)cc1 +CCOc1ccc(Nc2ncnc(Nc3cccc(C)n3)c2N)cc1 +Fc1ccc2c(c1)CCN(Cc1csc(-c3ccoc3)n1)C2 +COc1cc(NC(=O)NCCO)ccc1NC(C)=O +O=C(NC1CC1)c1cccc(OC(=O)C2CC=CCC2)c1 +COc1cccc(C(=O)Nc2nnc(Cc3ccccc3)o2)c1OC +CCCC(=O)N1CCC(C(=O)NCCNC(=O)c2ccccc2)CC1 +Fc1ccc(-c2cc(NCc3cc(C4CC4)on3)n3nccc3n2)cc1 +Cc1nccn1-c1ncccc1NC(=O)CCc1ccc(C#N)cc1 +Cc1cc(C(=O)N2CCC(C(=O)Nc3ccccc3)CC2)c(C)s1 +CC(C)Nc1cccc(CNC(=O)C(C)NC(=O)c2ccoc2)c1 +COc1cc(OC)cc(C(=O)Nc2sc3c(c2C#N)CCC3)c1 +O=C(Nc1nc(-c2ccco2)n[nH]1)c1ccc(OC2CCCC2)cc1 +Cc1nn(C)c(C)c1CC(=O)NCc1cscn1 +O=C(NCCCO)NCCS(=O)(=O)c1ccccc1 +Cc1cc(N)cc2nc(-c3cncc(Br)c3)oc12 +CCC(OC1CCCC1)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +CCOC(=O)C(Cc1ccccc1)NC(=O)c1ccc(C#N)c(C)n1 +O=C(CCC(=O)c1ccc(F)cc1)Nc1cccnc1 +CC(C)Cn1c(SC(C)C(N)=O)nnc1-c1ccccc1F +CC(=O)c1ccc(OCC(=O)NCC(C)C)c(N)c1 +O=C(NCc1cc(-c2ccncc2)n(C2CCCC2)n1)c1ccco1 +Cc1cc(C(=O)N2CCN(C)C3(CCNC(=O)CC3)C2)nc(C)n1 +C=CCOC(=O)c1cccc(S(=O)(=O)NC2CCCC2)c1 +Cc1ccc(C)c(NCc2nnc(C(C)(C)C)o2)c1 +CCNC(=O)N1CC(N2CCc3ccccc3C2CC(=O)N(C)C)C1 +CC(C)CC(NC(=O)c1ccc(Cl)cc1)C(=O)N1CCC1 +CCn1nc(-c2ccc(Cl)cc2)cc(C#N)c1=O +CC(C)NC(=O)CNC(CO)c1ccc(Cl)c(F)c1 +CC(C)NC(=O)COc1cc(O)c2c(c1)OC(C)(C)CC2=O +Cn1c(CS(=O)(=O)c2ccccc2)nnc1SCC#N +Cc1n[nH]c(SCC(=O)N2CC3CC(C2)c2cccc(=O)n2C3)n1 +COC(=O)c1cccc(C(=O)NC(C(=O)N(C)C)c2ccccc2)n1 +CCn1nc(-c2c(C)cc(C)cc2OC)cc(N)c1=O +Cn1cc(S(=O)(=O)N(Cc2ccccn2)C2CC2)cn1 +NC(=O)CCSc1ccccc1NC(=O)NCc1cccc(F)c1 +Cc1cccc(C(C)C)c1NC(=O)c1ccnc(OC2CCC2)c1 +Cc1cc(O)c2c(C)c(CC(=O)N3CCC(O)CC3)c(=O)oc2c1 +CCOc1ccc2c(c1)CCNC2C(O)c1ccccc1 +Cc1ccc(OCC(=O)NCCC(=O)N2CCNCC2)cc1 +CC(C)NC(=O)c1ccccc1NC(=O)C(C)Sc1ccccn1 +COCc1cc(C(=O)NCCCn2cccn2)ccc1F +Cc1nc2c3ccccc3nc(SCCCO)n2n1 +CCN(CC)c1nc(C)cc(C(=O)NCc2c(C)nn(C)c2C)n1 +Cc1cccc(C)c1OC1CCN(C(=O)Cc2c(C)noc2C)CC1 +CC(=O)N1c2ccc(C(=O)Cn3cnc(C#N)n3)cc2CC1C +CCC1C(=O)NCCN1C(=O)c1cnc(C)c(C)c1 +N#Cc1ccc(Cl)cc1NCCC(=O)NCc1ccncc1 +Fc1c(Cl)cccc1-c1nn2c(-c3cnccn3)nnc2s1 +Cc1noc(C)c1CNC1(c2noc(C3CC3)n2)CCCC1 +O=C(Cn1c(=O)oc2ccccc21)N1CCOCC1 +CCOc1ccc(OCC)c(NC(=O)NCc2ccncc2)c1 +CC(NC(=O)NCCC1(C)OCCO1)C1CCC1 +COCCNc1ncnc2c1cnn2-c1ccccn1 +O=C1CCCN1CC(=O)N1CCCC(c2ccn[nH]2)C1 +O=C(CNc1cccc(C(=O)N2CCCCC2)c1)N1CCCCC1 +Cc1onc(-c2ccccc2Cl)c1C(=O)NC(C)c1ccncc1 +CC(Oc1ccccc1)C(=O)Nc1nccn(C)c1=O +Cc1csc(NC(=O)NCc2nnc(C(C)C)n2C)n1 +NC(=O)NCC(=O)Nc1ccc(Oc2ccccc2)cc1 +COc1ccc(C(C#N)NS(C)(=O)=O)cc1OC +O=C(NC1CC1)c1nn(-c2ccccc2)c2c1CCC2 +Nc1nc2nonc2nc1Nc1cccc(Br)c1 +CCCCC(=O)N1CC=C(c2c[nH]c3ncccc23)CC1 +COCc1nn(Cc2cn(-c3ccc(F)c(Cl)c3)nn2)c(=O)o1 +CCOC(=O)C1(NC(=O)c2cc3ccccc3oc2=O)CCCC1 +CC(=O)Nc1cccc(NC(=O)NC(C2CC2)C2CC2)c1C +Cc1noc(NC(=O)CCc2c(C)nn(C)c2C)n1 +Cc1cc(NC(=O)C(C)S(=O)(=O)c2cc(F)ccc2F)no1 +Cc1c(CCC(=O)NC(C)C2CC2)c(=O)[nH]c2c1c(=O)[nH]n2C +CC(C)Nc1ncnc(Nc2ccc(S(C)(=O)=O)cc2)c1N +CC(C)(C)OC(=O)NCc1ncc(-c2ccccc2)cn1 +Cc1nc(Cc2nnc(SC(C(=O)N(C)C)C(C)C)o2)cs1 +O=S(=O)(Cc1ccccc1F)Nc1ccc(F)cc1 +COc1cc(CCc2cc(N)on2)cc(OC)c1OC +COc1cccc(Nc2ccccc2C(=O)N2CCOC(C#N)C2)c1 +Cc1cc(C(=O)COc2ccccc2Cl)c(C)[nH]1 +Cc1ccc2c(c1)nc(C(=O)Nc1ccccc1)n2C +COC(=O)c1cc(CNC(=O)Nc2ccccc2N(C)C)oc1C +CNC(=O)c1ccc(CNS(=O)(=O)c2cc(F)ccc2F)cc1 +COC1CCCCC1OC(=O)c1cncc(F)c1 +CCCNC(=O)CNC(=O)NCC(C)(C)N1CCOCC1 +O=C(Oc1ccc2ccccc2c1Br)N1CCOCC1 +COCc1ccc(C(=O)OC(C)Cn2cccn2)cc1 +CCc1nc(CNc2cc(Cl)cc(Cl)c2)no1 +CCc1c(C(=O)CNc2cc(C#N)ccc2C)[nH]c(C)c1C(C)=O +COc1cccc(-n2nnc(S(=O)(=O)c3ccccc3)c2C)c1 +Cc1cc(C(C)NC(=O)C(C)Sc2nncs2)c(C)o1 +CNC(=O)Cc1ccc(NC(=O)NC(C)CCC(C)(C)C)cc1 +Cc1cccc(CNC(=O)c2cc(-c3ccc(F)cc3)[nH]n2)c1 +CC(=O)OC1CC(C)N(C(C)=O)c2ccc(C)cc21 +CCN(CC(F)(F)F)C(=O)CCc1ncc(-c2ccccc2)o1 +CCc1nn(-c2cccc(Cl)c2C)c2c1CNCC2 +COc1ccc2c(c1)c(-c1nc(N(C)C)ncc1C#N)cn2C +CN(CC1CC1)C(=O)CN1CCOc2ccc(F)cc21 +Cc1cc(O)ccc1NCc1c(C)cc(O)cc1C +Cc1sc(-c2ccccn2)nc1-c1ccc2c(c1)NCCO2 +CC(C)COCCNC(=O)NCc1ccccc1Cl +CC1CCc2nc(N)c(C(=O)Nc3ncccn3)cc2C1 +O=C(NCCCCN1CCOCC1)C1CC(=O)N(c2ccccc2)C1 +O=C1NCCN(C(=O)Nc2ccncc2)C1c1ccccc1 +CC(=O)Nc1ccc(OC(=O)CCC2CCCC2)cc1 +CN(C)C(=O)c1ccccc1SCc1ccsc1 +O=C(Nc1cccnc1-n1cccn1)C1CC=CC1 +COc1cc(OC)cc(C(=O)NCC2CCCCO2)c1 +COc1ccc(S(=O)(=O)NC(C)C2CCCO2)cc1F +CC1CCCCN1C(=O)C1CC(=O)N(CCc2ccccc2)C1 +O=C(CSc1ccncc1)OCC(=O)N1CCCc2ccccc21 +COc1ccc(C(=O)NCCNC(=O)NC2CCCC2)cc1 +COC(=O)c1coc(S(=O)(=O)NC2(C)Cc3ccccc3C2)c1 +O=C(CSc1ccc(F)cc1)Nc1nnc(-c2ccccc2)o1 +CC(Sc1ccc(Cl)cc1)C(=O)NC1c2ccccc2CC1O +COCCNC(=O)CNC(=O)c1cccc(-n2cccc2)c1 +Cc1cccc(CN2C(=O)CCC3C2CCN3S(C)(=O)=O)n1 +O=C(NCc1cc(Cl)ccn1)Nc1ccccc1N1CCCC1 +CCC(=O)Nc1ccc2c(c1)CC(C(=O)NCCCOC)CO2 +CC(=O)NCCNC(=O)c1ccccc1Nc1cccc(C)c1C +Cn1nnnc1SCC(=O)N(C1CCCCC1)C1CCCCC1 +CCOC(=O)N(C)CC(=O)NCC#Cc1ccccc1 +CCOc1ccc(CCC(=O)n2nc(C)cc2C)cc1 +Cc1csc(CNc2cccc(OC(F)(F)F)c2)n1 +CN(CCc1ccccc1)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +COCCOc1cccc(CNC(=O)c2cc3cc(F)ccc3[nH]2)c1 +CCC(=O)N1CCCN(C(=O)NCc2ccc(OC(C)C)cc2)CC1 +COc1ccc(-c2cnc(CN(C)C(C)c3ccco3)o2)cc1 +CN(Cc1nccn1C(F)F)C(=O)Nc1ccccc1-n1cccn1 +CNC(=O)C1CCN(C(=O)c2n[nH]c(=O)c3ccccc23)CC1 +O=C1CN(C(=O)c2csc3nc(-c4ccc(F)cc4)cn23)CCN1 +CCCNC(=O)COc1ccc(Cl)cc1C(C)O +Cc1cc(C)cc(C(=O)Nc2cccnc2-n2ccnc2C)c1 +CCCN(CCO)C(=O)Nc1c(C)c(C2CC2)nn1-c1ccccc1 +O=C(NCc1noc(Cc2ccccc2)n1)c1ccc(Cl)cc1 +CN(C)C(=O)CSc1nnc(-c2cccs2)n1C1CC1 +CN(Cc1nc(-c2cccc(Cl)c2)no1)S(C)(=O)=O +CCOC(=O)C1CC(=O)N(C(C)c2ccccc2)C1 +Cc1noc(C)c1C(=O)OCC(=O)NCc1cccs1 +Cn1cc(CNC(=O)Nc2ccccc2C(=O)N2CCOCC2)cn1 +COc1ccc(C2CC(O)=Nc3c2cnn3C2CCCC2)cc1OC +CC(O)CN1CCN(C(=O)c2occc2-c2ccccc2)CC1 +CC(C)n1nccc1NC(=O)N(C)Cc1ccc(Cl)cc1 +O=C(NCCNC(=O)C1CC(=O)N(c2cccc(Cl)c2)C1)C1CC1 +CC(Oc1cccc(C#N)c1)C(=O)Oc1cccc(-n2cccn2)c1 +O=C(c1cc[nH]n1)N1CCC(COc2ccccn2)CC1 +Cc1ccc(C)c(CN(C)CC(O)c2ccccc2)c1 +COc1ccc(NS(=O)(=O)Cc2cccc(C)c2)cc1OC +CCOc1cccc(C(C)NC(=O)CCn2c(C)c(C)sc2=O)c1 +CC(C)NC(=O)COC(=O)c1cc(Cl)ccc1OC(C)C +NS(=O)(=O)c1cnc(N2CCN(c3ccccc3)CC2)s1 +COc1ccc(CN(C)Cc2cnc(C)s2)cc1OC(F)F +C#CCOc1ccc(F)cc1NC(=O)Cc1cccc(F)c1F +COCCNc1ccc(S(=O)(=O)NC(C)C)cc1 +Cc1ccc(F)cc1NC(=O)CCC(=O)c1ccccc1 +Cc1ccc(C(C(=O)NCC(F)F)N(C)C)cc1 +Cc1cc(=O)c(C(=O)N2CC(C(C)C)Nc3ccccc32)c[nH]1 +CC(=O)NCc1ccc(C(=O)NCC2CCCO2)cc1 +CC(=O)N1CCCN(C(=O)Nc2ccc(C#N)cc2)CC1 +COc1ccc(C(=O)COC(=O)c2ccc(F)cc2F)c(OC)c1 +COc1ccc(C)cc1CC(=O)NCc1ccccc1Cn1ccnc1 +Cc1c(C(=O)NCC(C)O)cnn1-c1ccc(F)cc1 +Cc1ccc(C)c(Cn2cccc(C(=O)Nc3nccs3)c2=O)c1 +Cn1nc(-c2ccccc2)cc1C(=O)NCCc1ccsc1 +N#Cc1ccc(C(=O)Nc2ccc(F)cc2F)c(F)c1 +CCOc1cc(CNC(=O)Nc2ccccc2)ccc1OC(F)F +CC(NC(=O)c1ccn2ccnc2c1)C1COc2ccccc21 +Cc1ccc2c(CN3CCOC(C(N)=O)C3)cc(=O)oc2c1 +CC(C)CNC(=O)c1cccc(NC(=O)C(C)Oc2ccccc2)c1 +CC(C)n1nccc1NC(=O)NCC1(C(N)=O)CCOCC1 +COC(=O)N1CCC(NC(=O)N(C)C(C)c2ccccc2F)CC1 +O=C(Nc1ccc(Cn2cccn2)cc1)C1CC2CCC1O2 +COc1ccc(CCC(=O)Nc2nc(-c3ccccn3)cs2)cc1 +Cc1ccc(N2CCC(Sc3nc4ncccn4n3)C2=O)cc1 +CCOc1cc(NCCC(=O)N2CCCC2)ncn1 +CCN1C(=O)C(C)(C(=O)Nc2cccnc2)Sc2ccccc21 +N#CCn1ccc2cc(Br)ccc2c1=O +Cc1ccc(-c2nnco2)cc1NC(=O)N(C)C(C)CC#N +Cc1ccc2oc(N3CC(CO)C(CN4CCOCC4)C3)nc2c1 +CN(CCO)C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCOC(C)c1noc(CN2CCCC2c2noc(C)n2)n1 +O=C1CC2CCC(CN1)N2C(=O)c1ccc(F)c(O)c1 +CCOc1ccc(F)c(C(=O)N(C)CCc2ccc(F)cc2)c1F +O=C1CCC(C(=O)Nc2ccc(-c3cn4c(n3)SCC4)cc2)N1 +Cc1ccc(NC(=O)C2(c3ccccc3F)CC2)c(O)c1 +COc1ccc(C(=O)NCCOc2cccc3cccnc23)cc1 +O=C(COc1ncnc2sccc12)Nc1ccc(F)c(F)c1F +Cc1cccc(NC(=O)c2ccn(C)c(=O)c2)c1C(N)=O +O=C(NCc1ncc[nH]1)Nc1ccccc1C(=O)N1CCCCC1 +CN(Cc1ccccc1OC(F)(F)F)C(=O)NCc1ncn(C)n1 +COCC(C)N1CCN(C(=O)CSc2ccccc2)CC1 +O=C(NCC(F)(F)F)c1ccccc1OCc1cscn1 +O=c1ccc(C(F)(F)F)cn1Cc1nnnn1-c1ccccc1 +O=C(c1ccc(F)cc1)N1CCCC1Cc1ccccc1 +CCCCC1CCC(C(=O)NC2CC(O)C(CO)C2)CC1 +Cc1ccc(C(=O)Nc2ccccc2C(=O)NCc2ccco2)c(C)c1 +CCn1c(C(=O)NC(C)(C)C)cc2sccc21 +COc1ccc(Nc2ccc(C#N)cc2N)c(OC)c1 +COc1cccc(NC(=O)c2coc(=O)c3ccccc23)c1 +NC(=O)NCCC(=O)NCc1ccc(-c2ccc(Cl)cc2)o1 +CCn1cc(CNc2ccccc2C(F)(F)F)cn1 +CCC1CCCN(C(=O)c2ccnc(SC)c2)C1 +c1ccc2c(c1)N(CCn1cncn1)CC21CCCC1 +CCc1ccc(C(O)c2ccc3c(c2)OCCO3)s1 +O=C(Nc1ccccn1)NC(C(F)(F)F)C(F)(F)F +Cc1cc(-n2cccc2)ccc1C(=O)NCCc1nnc2n1CCC2 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1ccccc1N1CCCC1=O +Cc1nnc(-n2cc(Br)cn2)c2ccccc12 +COc1ccc(-c2cc3n(n2)CCCN(C(=O)c2ccco2)C3)cc1 +Cc1c(F)cccc1NC(=O)c1c[nH]nc1-c1ccccc1F +COc1ccc(OC)c(NCc2cc(Cl)c(O)c(OC)c2)c1 +Cc1nc(-c2ccccc2)sc1CNC(=O)c1ccncc1F +CC(C)N(C(=O)c1ccc(OCC(F)(F)F)nc1)C1CCC1 +COc1cc(C(=O)NCCC(=O)NCc2ccncc2)ccc1C +Cc1ccc(CNC(=O)Nc2nnc(C(F)(F)F)s2)c(C)c1 +O=C(NCC1CCCCC1)c1cn[nH]c1-c1ccccc1 +Cc1ncsc1CCNC(CO)c1ccccc1 +O=C(CNC(=O)c1ccccc1)NCc1cscn1 +CC(=O)NC(C)(C)c1noc(-c2cnc3ccc(C)cn23)n1 +CC(OC(=O)c1c(Cl)cccc1Cl)C(=O)NC1CC1 +OCCN(Cc1ccccc1)c1cc(CO)ccn1 +CC1(C)CCCC1NC(=O)NCCCCn1ccccc1=O +O=C(CN1CCOCC1)n1c2c(c3ccccc31)CCCC2 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCN(CC(F)F)CC1 +CC(C)Oc1cccc(NC(=O)c2cnccc2C(F)(F)F)c1 +Cc1csc(NC(=O)Cc2ccc3ccccc3c2)n1 +O=C(NCc1ccncc1)NCC(O)c1cccc(C(F)(F)F)c1 +CCOc1ccc(F)cc1NC(=O)Cc1nc(-c2ccco2)oc1C +COc1ccc(S(=O)(=O)NCc2ncn(C)n2)c(C)c1C +Cc1cc(C(=O)NCc2ccoc2)c(C)n1C1CC1 +CC(Oc1ccc(C(C)(C)C)cc1)C(=O)N1CCOCC1 +O=C(Nc1ccnn1Cc1ccccc1)c1cc(=O)c2ccccc2o1 +O=S(=O)(c1ccccc1F)N1CCN(c2ccccc2)CC1 +CC(O)CCN(C)C(=O)NC(C)Cc1ccsc1 +CCNC(=O)CSc1nc(C(C)(C)C)nc(C)c1C(=O)OC +COc1ccc(NC(=O)CN2C(=O)COc3ccccc32)cc1 +COCc1ccc(C2CCCN2C(=O)NCc2ccsc2)o1 +Cc1nn(-c2ccc(Cl)cc2)c(C)c1S(=O)(=O)N1CCCC1 +CC(C)c1cccc(NC(=O)c2cnc3snnc3c2)c1 +Cc1ccccc1NC(=O)Nc1ccc2[nH]c(=O)oc2c1 +Cc1cc(S(C)(=O)=O)ccc1NC(=O)CCC1CCCO1 +Cc1cc(C(=O)NC(C)C)nc(N2CCCCC2)n1 +Cc1ccc(CNS(=O)(=O)NCc2ccccc2F)cc1 +O=C1NCC(=O)N2CCN(C(=O)c3cc(-c4ccccc4)no3)CC12 +O=C(NC1c2ccccc2CC1O)C1CC1c1cccc(F)c1 +Nc1ccc2c(c1)N(C(=O)Cc1c[nH]c3ccccc13)CC2 +CNC(=O)c1cccc(CNc2ccc(C)cc2F)c1 +CC(C)CC1(C(=O)N2CCC(Cc3cnn(C)c3)C2)CCC1 +CC(C)=CCC1(CO)CCCN(C(=O)CCc2c(C)noc2C)C1 +CN(CC1CC1)C(=O)CNC(=O)c1cccc(Br)c1 +Cc1cc(CC(C)NC(=O)CC2=CCCCC2)[nH]n1 +CC(C)N(C(=O)CN1CCN(C(=O)c2cccs2)CC1)C(C)C +OCCn1nccc1C1CCN(c2ccc3nnnn3n2)CC1 +CCN1C(=O)Cc2cc(NC(=O)c3cn(C)nc3OC)ccc21 +O=C(Nc1cccnc1N1CCCC1)c1ccc(-n2ccnc2)nc1 +CCS(=O)(=O)N1CCN(Cc2nc(C(C)C)no2)CC1 +CCC(NC(=O)N(C)Cc1ccccn1)c1ccccc1OC(F)F +COc1cccc(CC(=O)Nc2ccc3c(c2)N(C(C)=O)CC3)c1 +O=C(NCC1CCOC1)c1cc(F)c(F)c(F)c1 +Cn1cccc1C(=O)NCc1ccccc1COCc1ccccc1 +O=C(Nc1ccc2nc[nH]c(=O)c2c1)C1(c2cccc(Cl)c2)CC1 +Cc1cccc2nc(-c3cccs3)c(C(C)O)n12 +COc1ccccc1C(=O)CNc1cccc(C(C)=O)c1 +CC1CN(C(=O)c2nn3ccccc3c2Cl)CC(C)O1 +CC(=O)c1ccc(NC(=O)c2ccc(Cl)cc2F)cc1 +COc1ccccc1CC(=O)Nc1ccccc1NC(=O)NC(C)C +CC(C(=O)N1CCN(C)CC1)N(c1cccc(F)c1)S(C)(=O)=O +CCN(CCCc1ccccc1C)S(C)(=O)=O +CC(NC(=O)CN1CCOCC1C1CC1)c1ccc(Cl)cc1 +Cc1ncc(CN(C)c2nc(-c3ccncc3)nc3c2CCC3)s1 +COc1ccc(C(N)C(=O)NC2CC2)c(OC)c1 +O=C(CCc1nc(-c2ccsc2)no1)NCc1ccc(F)cc1 +Cn1ccc(NC(=O)c2cc(Br)ccc2Cl)n1 +COCC(C)NC(=O)CSc1nc(C)cs1 +CC(C)N(C)S(=O)(=O)N1CCNCc2ccccc21 +NC(=O)c1oc2ccccc2c1NC(=O)c1cc2ccccc2oc1=O +COc1ccc(C(=O)Nc2cccc(Cn3cccn3)c2)nn1 +CCOC(=O)c1c(NC(=O)CC)sc2c1CC(C(C)C)OC2 +CC(=O)N1CCN(C(=O)CNc2c(C)cc(C)cc2C)CC1 +CNC(=O)COC(=O)CCC(=O)c1ccc(F)cc1 +CCOC(=O)CN(C(=O)c1cccc(F)c1)C(C)C +CCOC(=O)C(C)(NC(=O)c1scnc1C1CC1)C(C)C +O=C(c1ccc(-n2cnnn2)cc1)N1CCCC1c1cccs1 +CCc1ccc(C(=O)CNC(=O)c2ccco2)cc1 +COc1ccc2c(-c3cc4ccc(O)cc4oc3=O)cc(=O)oc2c1 +O=C(Nc1cc(Cl)ccc1N1CCCC1=O)c1ccccn1 +O=C(NCc1ccc(C(=O)N2CCCC2)cc1)c1ccccc1O +CC(C)(CNC(C(N)=O)c1ccccc1)c1ccc2c(c1)OCO2 +CCn1c(SCC(=O)Nc2ccccc2)nnc1-c1cccnc1 +NC(=O)c1ccc(Cn2cc(C(N)=O)c(-c3ccccc3)n2)cc1 +C=CCNC(=O)N1CCc2nc(NC(=O)NC3CCCC3)sc2C1 +COc1ccc(S(=O)(=O)NC(C)C(N)=O)c(N)c1 +COc1ccc2c(c1)C(O)C(NCc1ccccc1)C2 +COC(=O)Cc1ccc(OS(=O)(=O)N(C)C)cc1 +Cc1noc(C)c1CC(=O)NCCCc1cn[nH]c1C +CCCCNC(=O)C(C)Sc1nc2cc(F)c(F)cc2[nH]1 +Cc1ccc(CC(=O)Nc2cc(C#N)ccc2OC(C)C)cn1 +CC(C)n1nnnc1COc1ccc(C(=O)Nc2cnn(C)c2)cc1 +CC(C)NC(=O)CCC(C#N)c1ccc(Cl)cc1Cl +CCCn1c(SCc2ccccc2Cl)n[nH]c1=O +Cc1noc(C2CCN(C(=O)Nc3ccc(Cl)c(F)c3)CC2)n1 +COC(=O)c1ccc(NC(=O)C2(CC(=O)NC(C)C)CCCC2)cc1 +CCOCC1CCCN(C(=O)c2cccc(F)c2F)C1 +CC(=O)c1ccc(NC(=O)c2cn(-c3ccc(F)cc3)nn2)cc1C +O=C(COC(=O)Cc1cccc(F)c1)Nc1ccc(F)c(F)c1 +CCN(CCC#N)C(=O)COc1ccc(Cl)c(Cl)c1 +C#CCN1C(=O)C(Cc2cc(C)cc(C)c2)Oc2cc(N)ccc21 +O=C1NC2(CCN(C(=O)C3CC=CC3)CC2)CC1c1ccncc1 +Cc1nn(C)c(C)c1CNS(=O)(=O)c1ccc(CC(C)C)cc1 +Nc1c(C(=O)Nc2ccc3c(c2)OCO3)oc2cccnc12 +COC(=O)c1nc2c(cc1Br)CC=N2 +CCN(CC)C(=O)Nc1ccc(OC)c(NC(C)=O)c1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccccc1F +CCn1ncc(Br)c1C(=O)NCc1ccccc1OC +O=C(NCC(O)c1ccc(F)c(F)c1)Nc1nccs1 +CC(=O)NC(C)C(=O)Nc1ccc2oc(=O)[nH]c2c1 +Cc1nc(-c2nc[nH]n2)sc1C(=O)N(C)Cc1ccc(F)cc1F +CCOC(CC)C(=O)NCc1ccc(S(N)(=O)=O)s1 +CC1C(=O)N(c2ccccc2F)CCN1C(=O)Cc1ccccc1 +Cc1nc(-c2cccc(OCc3nnnn3C3CC3)c2)no1 +CC(C)Oc1cccc(C(O)CNC(=O)C2CCOCC2)c1 +COCc1ccccc1CNC(=O)c1cc(S(N)(=O)=O)c(C)o1 +COc1ccc(C(=O)N2CCN(c3ccccc3)CC2)c(F)c1 +Cc1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)cc1 +Cc1cc(=O)c(CO)nn1-c1cc(F)ccc1F +Cc1cc(CNC(=O)Nc2ccccc2-n2cccn2)ccc1F +Cc1ccccc1-c1nn(-c2ccccc2)cc1C(=O)NCCO +COc1ccccc1S(=O)(=O)Nc1ccc(C(=O)NC(C)C)cc1 +CC(C)n1nnnc1-c1ccc(NCc2cscn2)cc1F +CCOc1ccc(CCNC(=O)C(O)c2ccccc2)cc1 +Cn1nc2n(c1=O)CCN(CC(O)COc1ccc(C#N)cc1)C2 +CC(NC(=O)CCNS(=O)(=O)c1cccnc1)c1ccncc1 +N#CCCN(CCc1ccccn1)C(=O)Nc1ccc(F)cc1 +Cc1cccc2nc(C(=O)NCCC(C)(C)C)cn12 +CCS(=O)(=O)c1cccc(F)c1NC(=O)Cn1nc(C)cc1C +COc1ccc(C(=O)Nc2cccc(NC(C)=O)c2)c(OC)c1OC +CC(NC1CN(C(=O)OC(C)(C)C)CC1O)c1cscn1 +Cc1n[nH]c(C)c1CCOC(=O)c1ccc(NC(=O)C2CC2)cc1 +CCc1ccc(S(=O)(=O)NC(C)(C)C)cc1N +CCn1cc(S(=O)(=O)Nc2nc3cc(Cl)ccc3n2C)cn1 +Cc1cc(C)c(C(O)CN2CC(C)OC(C)C2)c(C)c1 +CC(C)(CNC(=O)c1c[nH]nc1-c1ccc(F)cc1)c1ccncc1 +COc1ccc(CNC(=O)c2cccc(C#N)c2)cc1NC(C)=O +Cc1noc(C2CCN(C(=O)NC3CC3)CC2)n1 +Cc1n[nH]cc1C(=O)N1CCCC(CCc2ccc(F)c(F)c2)C1 +CN(C)C(=O)CNc1ccc2c(c1)n(C)c(=O)n2C +COCC(=O)NCCn1ccc(C(F)(F)F)n1 +COc1ccc(Br)c(C(=O)N2CCCCC2)c1 +N#Cc1ccccc1NC(=O)CNc1ccc(Br)cc1 +CN(C(=O)COC(=O)C1CC2C=CC1C2)C1CCCCC1 +CC(=O)NCCNC(=O)c1ccccc1CCc1ccccc1 +O=C(NCc1cccc(O)c1)Nc1nncs1 +N#Cc1ccc(C(=O)NC(Cc2ccccc2)C2CC2)nc1 +NC(=O)CSc1nnc(-c2ccccc2)n1-c1ccccc1 +Cn1nc(C(=O)OCc2nc3ccccc3s2)ccc1=O +Cc1cc(C(C)NC(=O)c2cnns2)c(C)s1 +O=C(NCc1ccc(COCC(F)(F)F)cc1)Nc1nccs1 +CC(C)(C)NC(=O)N1CCC(CNC(=O)C2CC2)CC1 +Cc1ccc(C(=O)N2CCC(NC(=O)Nc3ccc(F)cc3)C2)cc1 +Cc1ncsc1CN1CC2COCC2(Cc2nnc(C3CC3)o2)C1 +COC(C)C(=O)Nc1ccc(F)cc1-n1cccc1 +N#CC1(C(=O)OCCCc2cccnc2)CCCC1 +O=C(NCC1CCCO1)c1cccc(-c2ccc(F)cc2)c1 +CN1CCC(N)C(=O)c2cc(Br)ccc21 +CC(C)CNC(=O)CS(=O)(=O)c1ccc(F)c(F)c1 +COC(=O)c1nc2c(c(=O)n(C)c(=O)n2C)n1C +CC(C)COCCC(=O)NC(C)c1ccc2c(c1)NC(=O)CO2 +Cc1ccc2oc(C(=O)N(C)CCc3noc(C4CC4)n3)cc2c1 +COC(=O)Nc1ccc(OCc2cc(F)cc3cccnc23)cc1 +CCN(Cc1ccco1)C(=O)NCc1ccccn1 +CN(C)c1ccnc(NC(=O)Cc2ccc(O)cc2)c1 +Cc1cncc(C(=O)NC(CO)CC(C)(C)C)c1 +CC1=NC(=O)C(CCC(=O)NC(c2cccs2)C(C)C)C(C)=N1 +O=C(Nc1ccc(O)cc1)c1cc(F)ccc1-n1cnnn1 +O=C(CCN1C(=O)c2ccccc2S1(=O)=O)NCc1ccco1 +O=C1CCc2cc(S(=O)(=O)Oc3ccc(F)c(F)c3)ccc2N1 +O=C(Nc1ccc(O)cc1)c1cccc(-n2cnnn2)c1 +COc1cc(CNC(=O)c2cc(C)sc2C)ccn1 +N#Cc1nnn(-c2cc(Cl)cc(Cl)c2)c1C1CC1 +Nc1cc(C(F)(F)F)c(Br)c(C(F)(F)F)c1 +CCCCS(=O)(=O)NCC(=O)N1CCc2ccccc2CC1 +CCCCc1nc2cc(Br)cnc2n1CCCC#N +Nc1c(C(=O)Nc2ccncc2)sc2ccccc12 +Cc1c(CNc2ncc(F)c(N(C)C)n2)oc2ccccc12 +O=C(COC(=O)CCc1c[nH]c2ccccc12)Nc1ccccc1 +CC(C)Cn1cc(C(=O)N2CCCCC2)c(=O)c2c(N)cccc21 +O=C(NCCCO)c1ccc(Oc2ccccc2)o1 +CCc1nnnn1CC(=O)Nc1ccc(F)c(Cl)c1 +Cc1cn(-c2ccc(CNC(=O)c3ccccc3)cc2)cn1 +Cc1cc(C)n(C(C)CC(=O)Nc2ccc(C)c(N(C)C)c2)n1 +Cc1nccc(NCc2cc3n(n2)CCCN(S(C)(=O)=O)C3)n1 +COc1cccc(NCC(=O)N2C(C)CCCC2C)c1 +CCc1nc(CC(=O)Nc2nc(C)c(C)s2)cs1 +Cc1cc(C)cc(C(=O)N2CCC(OCc3ccccc3C)CC2)c1 +Cc1csc(NC(=O)CCNC(=O)c2ccccc2)n1 +CCn1nc(C)c(Cl)c1C(=O)NCCC(C)C +COCc1cc(=O)[nH]c(Nc2cccc(F)c2C)n1 +CCOC(=O)c1cc(S(=O)(=O)N2CCN(C)CC2)cn1C +COCCn1nc(C(=O)Nc2nnc(C)s2)ccc1=O +Cn1c(CCNC(=O)CSc2ccc(F)cc2)nc2ccccc21 +O=C(CNC(=O)c1ccc2c(c1)CCC(=O)N2)NCc1ccco1 +CCC(C)OC(=O)CCNC(=O)c1ccc(Br)cc1 +COC(=O)N1CCC(NC(=O)c2cc3cc(F)ccc3[nH]2)CC1 +NC(=O)CSc1ccccc1NCc1cnn(-c2ccccc2)c1 +C#CCNC(=O)C(C)Nc1cccc(N2CCCCC2)c1 +COc1cc(C)c(C(=O)N2CCCC(O)C2)cc1OC +CCOc1ccc(OC(=O)c2ccc(=O)n(C)n2)cc1 +COc1ccc(-c2nc(-c3cc(C(N)=O)co3)cs2)cc1OC +Cc1cc(Cl)c2oc(C(=O)NC3CCOC3=O)c(C)c2c1 +Cc1cc(NC(=O)CCn2c(C)csc2=O)no1 +Cc1nnc2n1CC(NC(=O)Cn1ccc(C(F)(F)F)n1)CC2 +Cc1nc(-c2csc(S(=O)(=O)N3CCCCC3)c2)no1 +Cc1ccnc(NC(=O)CN(C)C(=O)c2ccsc2)c1 +COc1ccccc1C(C)NC(=O)C(C)Sc1nnnn1C1CC1 +CC(=O)c1ccc(NC(=O)N2CC(C)CC(C)C2)cc1 +O=C(c1cnccn1)N(CCc1ccccc1)Cc1ccccc1 +CN(CC(=O)NC1CC1)C(=O)C1(c2cccc(F)c2)CCC1 +Cc1nn(CC(=O)NCC(C)(C)c2ccncc2)c(C)c1Cl +CCn1c(SC(C)C(=O)NC2CC2)nnc1N1CCOCC1 +CCOC(=O)Nc1cccc(C(=O)NCCc2ccccn2)c1 +CCc1cc(C(=O)Nc2cccnc2N2CCCC2)sc1C +O=C(Cc1cccc(O)c1)NCc1cc(=O)[nH]c2ccccc12 +Nc1cc(NCc2ccccn2)nc(SCc2ccccc2)n1 +CC(C)NC(=O)C1CN(Cc2cccs2)CC12CCOCC2 +CCOc1ccccc1CNC(=O)c1n[nH]c(=O)[nH]1 +O=C(CN1CCc2ccccc2C1)c1cc(F)ccc1F +FC(F)n1ccnc1CSc1nnnn1-c1ccc(Cl)cc1 +C#CCOC(=O)C(C)Oc1ccc(SC)cc1 +Cc1ncc(-c2ccccn2)c(CN(C)C(=O)C(C)C)n1 +Cc1ccc2ncc(C(=O)N(CCC#N)Cc3ccco3)n2c1 +Cc1cc(C)cc(C(=O)NCC(=O)NCc2cccs2)c1 +NC(=O)c1cn(-c2ncc(Br)cn2)cn1 +O=C(c1ccoc1)N1CCCC(CO)(Cc2ccc(F)cc2F)C1 +CC(C)CC(c1ncnn1C)n1cc(-c2ccc(F)c(F)c2)nn1 +CC1CCN(C(=O)c2ccc(OCC(F)F)nc2)C1C +CCOc1ccc(NC(=O)c2ccc3c(c2)nnn3C(C)C)cc1 +N#CCc1cnn(-c2ccc(Cl)cc2)c1C(F)(F)F +Cn1ccnc1C(NC(=O)NCc1ccccc1)c1cccc(F)c1 +CCN(CC)C(=O)CSc1nnc(-c2ccccc2Cl)n1C +O=S(=O)(c1cccc(C(F)(F)F)c1)N1CCOCC1 +CCCCNC(=O)C(C#N)c1nccn1C(F)F +NC(=O)c1c(NC(=O)c2ccccc2F)sc2c1CCCCC2 +Cc1cc(NC(=O)c2csc(-c3ccc(F)cc3)n2)n(C)n1 +CCOc1ccccc1OCC(=O)N(C)C1CCc2ccccc21 +CCC(C)NC(=O)Nc1cc(C(=O)NC2CC2)ccc1C +CC(CC(=O)N1CCN(C2CCCC2O)CC1)C1CC1 +CSc1ccccc1C(=O)N1CCc2ccccc2C1 +Cc1nnc(CN2CCc3ncnc(N4CCOCC4)c3C2)n1C +O=C(NCc1ccc(Cn2cccn2)cc1)C1COc2ccccc2C1 +CC(C)C(NC(N)=O)C(=O)Nc1cccc(CN2CCCCC2=O)c1 +CNC(=O)Cc1ccc(NC(=O)NCc2ccncc2)cc1 +N#Cc1ccccc1S(=O)(=O)Nc1ccc(F)cc1F +CCOc1ccccc1-c1noc(CN2CCN(CCO)CC2)n1 +Cc1cccc(OCCCC(=O)Nc2nc(C)cs2)c1 +CCc1nnsc1C(=O)N1CCN(Cc2c(C)noc2C)CC1 +OCCn1c(-c2ccc(F)cc2)nc2cc3c(cc21)OCCO3 +COc1cccc(-c2nnn(-c3ccccc3Cl)c2N)c1 +CNC(=O)NC(C)(C)C(=O)N(C)CC1CCCCC1 +CCCC(=O)NCCS(=O)(=O)N1CCc2ccccc2C1 +CC(Cc1cccs1)N(C)C(=O)c1c[nH]c2c(cnn2C)c1=O +Cn1cnnc1C1CCCN(C(=O)c2cnn(C)c2-n2cccc2)C1 +CC(C)(C)CCNC(=O)COc1ccc(S(C)(=O)=O)cc1 +Cc1occc1C(=O)N1CCC2C1CCC(=O)N2Cc1ccncc1 +COC(=O)c1ccc(NC(=O)c2cccc3c2ccn3C)cc1 +CC1Cc2ccccc2N1C(=O)CCn1cncn1 +Cc1ccn2c(=NC(=O)c3cccc(-n4cncn4)c3)[nH]nc2c1 +COc1ccccc1-c1csc(CCN2CCOC2=O)n1 +CC(C)c1cc(C(=O)N2CCC2)c2ccccc2n1 +O=S(=O)(NCC1(O)CCOCC1)c1c(F)cccc1F +Cc1cccc2c1CCN2CC(=O)Nc1nccs1 +NC(=O)CN1CCN(c2ccc(C(F)(F)F)cn2)CC1 +Cc1ccccc1C1CC(=O)c2c(C)nc(N)nc2C1 +Cc1cnn(CC2CN(CCc3cccs3)CCO2)c1 +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)NCC1(C)CCCC1 +Cc1ccc(C(=O)CCC(=O)Nc2ccccc2O)s1 +Fc1cc2c(c(F)c1Cl)CCNC2C1CNC1 +COCC1CCCN1C(=O)c1cccc(CCC(C)(C)O)c1 +CCN(Cc1ccccc1C)C(=O)NCCCn1cccn1 +Cc1ccccc1CNc1ccc(C(N)=O)c(Cl)c1 +CCCn1nnnc1NCc1cccc(OCC)c1 +CC(OC(=O)c1nccc2ccccc12)c1nccs1 +CCOc1cccc(C(C)NC(=O)Cc2ccsc2)c1 +COC(=O)CNC(=O)CN(c1ccc(C)cc1)S(C)(=O)=O +Cc1nnc2n1CCN(Cc1ccc(-c3ccccc3C#N)cc1)C2 +Cn1c2ccccc2c2ncn(CCN3CCOCC3)c(=O)c21 +CCN(CC(C)C#N)C(=O)CSc1cccc(C)c1 +O=c1c2ccccc2ncn1CCOCCOc1ccccc1 +O=C(Cc1ccccc1O)NCCc1ccc(F)cc1F +CCCn1nc(C(=O)NCCCOC)ccc1=O +CCOc1ccc(-c2nnc(COc3ccccc3C#N)o2)cc1 +c1cncc(Cc2nncn2-c2cccc3ccccc23)c1 +Cn1cc(CCC(=O)Nc2cc(F)c(F)cc2Cl)cn1 +CCc1nc(CCOc2cccc(Cl)c2)sc1CO +CSc1nc(C(C)C)nc(C)c1C(=O)NC(C)C1CCCO1 +COc1ccc(C(=O)Nc2ccc(OC)c(N)c2)cc1 +Oc1ccc2cccc(NCc3cccnc3)c2c1 +COc1cccc(-c2nc(-c3ccc(N)cc3)cc(=O)[nH]2)c1 +CS(=O)(=O)N1CCCC(C(=O)Oc2cccc(F)c2)C1 +COc1cc(C#N)ccc1OC(=O)CCc1c[nH]c2ccccc12 +C#CCNC(=O)NCCc1ccc(OC(C)C)cc1 +O=c1cc(C2CCC2)ncn1Cc1nc(-c2ccccc2)no1 +CSc1nnc(NC(=O)CCc2c(C)[nH]c(=O)n(C)c2=O)s1 +Cn1ncc(Br)c1C(=O)N1CCCC1c1ccco1 +Cc1cc(C(=O)n2nc(C(F)(F)F)nc2N)c(C)n1CC1CC1 +COCc1cccc(C(=O)NCc2sccc2C)c1 +CCC(NC(=O)c1ccc(OC)cc1)c1nc2ccccc2[nH]1 +COc1ccc(NC(=O)CCN2C(=O)COc3ccccc32)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)CC1C=CCC1 +N#Cc1ccccc1COc1nnc2ccccn12 +Cn1ccc(C(=O)N2CCCN(c3ncccc3C#N)CC2)cc1=O +Cc1nc2c(-c3ccccc3C)csc2c(=O)[nH]1 +O=C(Cn1cnc2cc(F)c(F)cc21)Nc1ccc(F)cc1Cl +Cc1ncsc1-c1nnc(CNC(=O)c2cccc(F)c2)o1 +O=C(NC1(c2ccccc2)CCCC1)c1cnc(C2CCCO2)s1 +C#CCOC(=O)c1cc2cccc(Br)c2o1 +CCNC(=O)c1ccc(NCC(=O)Nc2ccccc2C)c(C)c1 +COc1ccccc1C(=O)CSc1ccccn1 +COCC(C)NC(=O)Cc1csc(-c2ccoc2)n1 +NS(=O)(=O)c1ccc(CNC(=O)CCCn2cccc2)cc1 +CC1CCCC(CNC(=O)CNC(=O)C(C)(C)C)C1 +Cc1noc(C2CCN(C(=O)CCc3nccs3)CC2)n1 +COCC(C)OC(=O)CCc1ccccc1Br +CNC(=O)c1ccc(CNC(=O)Nc2ccc(F)cc2C#N)cc1 +O=c1cc(-c2ccccc2Cl)[nH]n1-c1ccccc1 +Nc1ccc(NC(=O)c2ccccc2Br)cn1 +O=S(=O)(NC(CO)Cc1ccccc1)c1cccs1 +CCOC(=O)N1CCc2c(c(=O)[nH]c3c2c(C)nn3C)C1 +CC(O)(CNS(=O)(=O)c1ccc(F)cc1)C1CC1 +COC(=O)CC(C)NC(=O)c1ccc(-c2cnco2)cc1 +COc1ccc(C(C)=O)c(OC(=O)Cn2c(C)c(C)sc2=O)c1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCc3ccccc3C2)cc1 +O=C(CC1CC1)N1CCC2(CC(Oc3ncccn3)CO2)C1 +CC(C)CC(C#N)N(C)C(=O)c1ccccc1Cl +CCCOC(=O)C(C)Sc1nc2ccccc2c(=O)n1CC +CCn1c(SCc2ccccn2)nc2sc(C)cc2c1=O +CCC(CNC(=O)Cc1ccc[nH]1)Oc1ccccc1F +O=C(Cc1cccc(F)c1)NCC(=O)Oc1ccccc1F +CCNC(=O)c1ccc(CNC(=O)N2CCOCC2)cc1 +Cc1ccc(-c2nc(C(=O)NCc3ccnn3C)cs2)o1 +O=C(Cc1ccc(F)cc1F)Oc1cccc(C(=O)NC2CC2)c1 +Cc1ccc(C(=O)NCCOc2cccc(C(F)(F)F)c2)c(=O)[nH]1 +COC(=O)C1CCCN1CCC(=O)Nc1ccccc1C +CCc1noc(CN(C)C(=O)c2ccc(N3CCOCC3)c(F)c2)n1 +O=C(CSc1nnc(-c2cccnc2)o1)Nc1cccc(F)c1 +COc1c(Cl)cc(C(=O)N(CCO)C2CC2)cc1Cl +CC(=O)NC(C)C(=O)Nc1ccc(OC(F)F)cc1OC(F)F +Cc1ccc(-c2cc(CC(=O)N3CCOCC3)no2)cc1 +CCOc1ccc(NC(=O)N2CCC(n3cncn3)CC2)cc1Cl +N#Cc1ccc(-c2noc(CCn3cnc4ccccc43)n2)nc1 +CCC(C(=O)NCc1nnnn1-c1ccccc1)c1ccccc1 +CCC1COCCN1Cc1c[nH]nc1-c1cccs1 +O=C(NC1(c2ccccc2)CCC1)C1COCCO1 +Cc1nnc(CNC(=O)c2ccc(Cl)c3cccnc23)n1C +CCCCc1cc(NC(=O)c2cnc(C3CCCO3)s2)[nH]n1 +COCCCn1c(C2CCCO2)nc2ccc(Cl)cc21 +CC1Nc2nc(NC(=O)C(C)(C)C)[nH]c(=O)c2N(C)C1C +CC(C)(C)C(=O)N1CCCc2cc(C(O)CN3CCOCC3)ccc21 +Cc1cc(C2CCCN(C(=O)CCc3ccco3)C2)n[nH]1 +O=C(Cn1nnc(-c2ccccc2)n1)N1CCN(c2ccccc2)CC1 +O=C(NCC1Cc2ccccc2O1)c1ccc(=O)[nH]c1 +O=C(NCC(F)(F)F)NCC1(c2ccc(F)cc2)CC1 +O=C(c1cccs1)N1CC(c2nc(-c3cccnc3)no2)C1 +CCOC(=O)c1nn(-c2ccc(F)c(Cl)c2)cc1O +COc1ccc(NC(=O)c2cc(C(N)=O)cs2)cc1F +COCCNc1ncnc(Nc2ccc(Br)cc2)c1N +CCOc1ccc(CC(=O)N2CCN(CC(C)O)CC2)cc1 +CCOC(=O)N1CCN(c2ncnc3n[nH]cc23)CC1 +C=C(C)CN(CC)C(=O)CN1CCN(C(C)=O)CC1 +Cc1nc2cc(C(=O)NC(C)(C)c3cccc(F)c3)ccc2n1C +CCS(=O)(=O)N1CCC2C1CCN2Cc1cnn(C)c1 +Cc1nnc2c(Nc3ccc4c(c3)OCCO4)nc3ccccc3n12 +Cc1nnc(SCc2ccc(C(=O)N(C)C)cc2)n(N)c1=O +Cc1nn(-c2ccccc2)c(C)c1NC(=O)c1cccnc1 +COc1ccc(NC(=O)C2CCOC2)cc1OC(F)F +CC(C)Oc1ccccc1-c1ccc(CC#N)c(=O)n1C +O=C(CC(F)(F)F)N1CCN(C(=O)c2c(F)cccc2F)CC1 +O=c1c2ccccc2oc2nc3n(c(=O)c12)CCS3 +CC(=O)c1cccc(NC2OC(=O)c3ccccc32)c1 +CCCNC(=O)NCc1nc(-c2ccc(OC)cc2)no1 +Cc1cnc(CN(C)CC(c2cccs2)N2CCOCC2)cn1 +CCN(Cc1cc(Br)ccc1F)C(=O)C(C)NC(N)=O +CCn1c(=O)c2ccccc2n2c(Cn3cc(Cl)cn3)nnc12 +Fc1ccc(-c2csc(N3CCOCC3)n2)cc1F +CC(C)c1ccc(C(=O)N2CCN(c3ncccc3C#N)CC2)cc1 +Cc1occc1C(=O)Nc1nc(-c2ccc(F)cc2F)cs1 +O=C(COc1ccccc1F)NCC1CCN(c2ncccn2)CC1 +CCOc1ccccc1N=C(O)CCS(=O)(=O)c1ccccc1 +CCOC(C)c1noc(CNC(=O)N2CC(C)c3ccccc32)n1 +CCN(C)C(=O)c1cccc(OC(=O)CSc2ccc(C)cc2)c1 +Cn1cccc1C(=O)Nc1ccc(OCC(F)(F)F)cc1 +O=C(Nc1nc(-c2ccncc2)ns1)c1cncc(F)c1 +Cc1cc(C)cc(NC(=O)Cn2nc3n(c2=O)CCCCC3)c1 +Cc1nncn1-c1cccc(NC(=O)CCn2cccn2)c1 +COc1ccc(CN(C)C(=O)NCC(C)C)c(OC)c1 +CCNC(=O)c1cccc(NC(=O)c2ccoc2)c1 +CCOc1ccc(C(=O)N(C)Cc2ccc3c(c2)OCCO3)cc1 +CCC(C)Nc1ncnc(N2CCC(C(=O)OC)CC2)c1N +CCCS(=O)(=O)NCc1coc(-c2ccc(C)cc2)n1 +CCCNC(=O)N1CCC(n2c(C)nc3cccnc32)CC1 +CN(CC(=O)OC(c1ccccc1)c1cccnc1)S(C)(=O)=O +Cc1csc(CNC(=O)c2cn(C3CCCCC3)nn2)n1 +CCOc1cc(CN(C)C(C)c2sc(C)nc2C)ccc1OC +C#CCN1CCC(C(=O)Nc2c(C)cccc2C)CC1 +CCCOC(=O)c1sc2nc[nH]c(=O)c2c1C +Cc1cc(C(=O)N2CCN(CC(F)(F)F)CC2)no1 +Nc1ccccc1Oc1ccccc1S(N)(=O)=O +O=C(c1scnc1C1CC1)N1CCC(S(=O)(=O)NC2CC2)C1 +Cc1cnn(CCC(=O)NCC(C)(C)c2cccs2)c1 +CC(=O)N1CCCC1C(=O)NC(C)Cc1ccccc1F +CC(C)CC(=O)Nc1ccc(NC(=O)Cc2ccc[nH]2)cc1 +COCc1ccc(C(=O)NCCNc2ncc(Cl)cc2Cl)o1 +COCC1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +Cc1nn(C)c(C(=O)Nc2sc3c(c2C#N)CCC3)c1Cl +Cc1ncsc1C(=O)NCCNC(=O)c1ccco1 +Nc1ccc(C(=O)Cc2ccccc2Br)o1 +CSc1ccccc1NC(=O)NCC1CN2CCCCC2CO1 +NS(=O)(=O)c1ccc(C(=O)NC2CCCCCC2)cc1 +COc1ccccc1NC(=O)NCCc1nc2c(F)cccc2n1C +Cc1cc(C)cc(NC(=O)CSc2nnnn2-c2cccnc2)c1 +CCC(CC)NC(=O)C(C)Sc1ncn(-c2ccccc2)n1 +CC(Oc1ccccc1)C(=O)NCCCn1ncccc1=O +O=C(CC(F)(F)F)N1CC2CCC(C1)N(Cc1ccccc1)C2=O +CCC(=O)N1CCCC(C(=O)NCc2cccc3ccccc23)C1 +CC(CN1CCCC1=O)NS(=O)(=O)N1CCCCC1 +Cc1cnc(NC(=O)Cc2c(F)cccc2Cl)s1 +Cn1cnc(CNC(=O)NC2(c3ccccc3)CCCCC2)n1 +COc1ccc(C2(O)c3ccccc3NC(=O)C2OC)cc1 +O=C(CCc1ccccc1)NCc1ccc(-n2ccnc2)nc1 +COC(=O)c1nccc2c(C)ccc(Br)c12 +Cn1cc(C(=O)Nc2ccc(F)c(F)c2)ccc1=O +Cc1ccc(C(=O)c2ccc3c(c2)OCCCO3)cc1N +CN1C(=O)NC(c2ccccc2)C2=C1CN(CC1CCCO1)C2=O +CC(C)Cc1nc2cc3c(cc2n1CCCO)OCO3 +Cc1ccc(CNC(=O)c2cc(C)n3nccc3n2)cc1C +CCOCc1cccc(CNC(=O)Nc2cn[nH]c2)c1 +CN(Cc1nc2ccccc2s1)C(=O)c1cccc(OC(F)F)c1 +COCCNS(=O)(=O)c1ccc(C)c(C(N)=O)c1 +CCOC(=O)c1cn2c(ccc3c(C)cc(C)nc32)n1 +CCCNC(=O)CCNC(=O)N(C)Cc1ccc(C#N)cc1 +COC(CNC(=O)CNC(C)=O)c1ccccc1 +COCC(NC(=O)CC(C)c1ccccc1F)C(N)=O +CNC(=O)c1cccc(CCNC(=O)NC(C)Cn2cncn2)c1 +CCCC1CN(Cc2cnc(C3CC3)s2)CCO1 +CCN1CCN(C(=O)c2nccc3c(N)cc(Cl)cc23)CC1 +Cc1cc(C(=O)OCC(=O)NC2CCC(C)CC2)c(C)n1C1CC1 +COc1ccc(Br)cc1CSc1ncccc1N +CCC(NC(=O)NCCc1ccc(F)cc1C)c1nccs1 +Nc1cc(Cl)ccc1SCC(=O)N1CCOCC1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(F)cc2F)cc1 +O=C(NC1CCCc2ccccc21)N1CCOCC1 +CC(=O)NC1CCC(CC2CCC(NC(C)=O)C(C)C2)CC1C +Cc1nn(Cc2ccc(F)cc2)c2c1C(=O)CCC2 +CN(CC(N)=O)C(=O)c1ccc(NS(C)(=O)=O)cc1 +C=CCCCN(C)C(=O)c1cc2cccc(OC)c2o1 +O=C(NCCNC(=O)C1CC1)c1cc(Br)ccc1O +Cc1csc(C2CC3CN(C(=O)c4ccco4)CCC3O2)n1 +COc1cccc(CC(=O)N2CCc3c([nH]c4ccnn4c3=O)C2)c1 +CCn1ccc(C(=O)N2CCN(c3ncccn3)CC2)n1 +CNC(=O)COC(=O)CNC(=O)c1cc(C)cc(C)c1 +COCCOc1ccc(CNC(=O)C2COc3ccccc3C2)cn1 +Cc1cc(C2CCCN2C(=O)C2CCCN(C(N)=O)C2)on1 +CCC1COCCN1Cc1cc(F)c(F)cc1F +CC(C)(C)CC(NC(=O)N1CCN2C(=O)NCC2C1)C(F)(F)F +CN(CC(=O)Nc1ccc(-c2cc[nH]n2)cc1)c1ncnc2[nH]cnc12 +CN(C)c1ccc(-c2cc(C#N)nn2CC(O)CO)cc1 +Cc1csc(C(C#N)C(=O)c2cnn(C)c2-n2c(C)ccc2C)n1 +COCCNC(=O)c1cc(-c2cccc(OC)c2)no1 +Cn1ncc(C(=O)Nc2cccc(C(F)(F)F)c2)c1N +COCCNC(=O)Cn1nc(C(F)(F)F)c(Br)c1C +COCC#CCN(c1ccc(C(C)=O)cc1)S(C)(=O)=O +Nn1c(C(F)(F)F)nc2ccc(Cl)cc2c1=O +CC(=O)c1cc(F)ccc1OS(=O)(=O)c1cccs1 +O=C(Nc1cccc(-c2noc(-c3cccnc3)n2)c1)c1cccs1 +C#CCOc1ccc(C(=O)Nc2cccc(C)c2)cc1 +Cc1noc2ncn(CC(=O)NCC(C)c3ccccc3)c(=O)c12 +O=C(Nc1ccc2c(c1)CCO2)c1cc(Cl)ccn1 +O=C(Cn1c(=O)[nH]c2ccccc21)NC1CCCCC1 +Cc1cc2cccc(NC(=O)NCC(=O)NC(C)C)c2o1 +CCOc1cccc(-c2nn3c(=O)c(C)nnc3s2)c1OCC +CN(CCC#N)C(=O)CSc1cccc(C(F)(F)F)c1 +CN(CCCc1ccccc1)C(=O)c1ccccc1N1CCOCC1 +CC(Nc1cnn(C)c1)c1ncc(-c2ccc(Cl)cc2)o1 +c1ccc(CCSc2nnnn2C2CCCCC2)nc1 +CN(Cc1ncnn1C)c1nc2ccccc2nc1N1CCCC1 +COCC(C)NC(=O)Nc1ccc(Cl)c(Br)c1 +Cc1noc(COCC(=O)Nc2cc(Br)ccc2F)n1 +Cc1ccc(CN2CC(C(=O)N(CC(C)C)C3CC3)CC2=O)cc1 +CCc1ccc(-c2c(C)sc3ncc(CO)n23)cc1 +Cc1cccc(NC(=O)C(C)CS(=O)(=O)N2CCNCC2)c1 +CC(=O)c1ccc(OCC(=O)Nc2nc3ccc(F)cc3s2)cc1 +CC(C)(C)C1CSc2nnc(-c3ccco3)n2N1 +CC(C)n1nnnc1SCc1cn2cc(Cl)ccc2n1 +CC1Oc2ccccc2N(CCC(=O)N(C)CC2CCCO2)C1=O +Cc1noc(NC(=O)c2ccc(C)c(NC(=O)c3ccccc3)c2)n1 +Cc1nccc(CNC(=O)NC2CCC(C)(C)c3ccccc32)n1 +CCN(CC(=O)Nc1ccccc1OC)C(=O)c1cccs1 +CCNC(=O)CNC(=O)Nc1ccc(F)cc1C#N +Cc1noc2ncn(CC(=O)Nc3ccc(Cl)cc3)c(=O)c12 +Cc1cc(NC(=O)C2CCN(c3ccc(=O)n(C)n3)CC2)on1 +C=CCn1nnc(NC(=O)c2cccc(Br)c2)n1 +CN(Cc1cccnc1)C(=O)c1occc1CSc1ccccc1 +CC(C(N)=O)n1cc(-c2cc(F)cc(C(F)(F)F)c2)cn1 +COc1ccc(C(=O)Nc2ccc3c(c2)OCCCO3)cn1 +Cc1ccccc1-n1nc(C(=O)N2CCOCC2)nc1-c1ccccc1 +CCc1cc(Br)ccc1OC1CNC(C(=O)OC)C1 +CN(C)C(=O)c1ccc(-c2ccc3ncccc3c2)s1 +COC(=O)Cc1c(C)nc(-c2ccccc2F)[nH]c1=O +CCc1ccsc1C(=O)NCC(=O)N1CCCCC1 +CC(=O)c1cccc(NCCC(O)c2ccc(F)cc2)c1 +Cc1cn(CCC2=CCCCC2)c(=O)c(C#N)c1C +O=S(=O)(Cc1cccc(C(F)(F)F)c1)NCc1ccc(O)cc1 +O=C(Cn1c(=O)cnc2ccccc21)Oc1cccc(C(F)(F)F)c1 +O=C(Cc1csc(-c2ccoc2)n1)Nc1ccc(F)c(F)c1 +COc1ccccc1CNc1ncnc2c1cnn2-c1ccc(F)cc1 +COc1ccccc1CNC(=O)NCCn1ccnc1 +O=C(c1ccc(F)cc1)N1CCN(c2nc3ncccc3o2)CC1 +COC(=O)c1ccc(Oc2cc(-n3nc(C)cc3C)ncn2)cc1 +CCCc1nnsc1C(=O)N(Cc1ccoc1)Cc1cccs1 +Cc1nnc(SCC(=O)NCc2ccccc2)n1C +Cc1nc(CN2CCOC(c3ccccn3)C2)no1 +COc1cccc(CC(O)c2cccc(OC)c2)c1 +COc1ccc(Cc2nnc(-c3cccnc3)s2)cc1 +CC(OC(=O)COc1ccc(Br)cc1Cl)C(N)=O +CC(=O)N1CCN(c2cc(N3CCOCC3)cnn2)CC1 +CC(C)c1cccc(C(C)C)c1NC(=O)c1ccc(=O)[nH]c1 +CCc1c(C(=O)N2Cc3cnc(CC(C)C)nc3C2)csc1C +CCCNC(=O)Cn1nnc(CO)c1-c1cccc(Cl)c1 +Cc1ccc(S(=O)(=O)N(C)CCOCC2CC2)c(Cl)c1 +CC(C)CC(C(=O)N1CCc2[nH]ncc2C1)N1CCCCC1=O +CN(C)C(=O)Cn1cc(NS(=O)(=O)c2cccc(C#N)c2)cn1 +Cc1nc(-c2cccc(CNC(=O)CCC(C)(C)C)c2)n[nH]1 +CCNC(=O)CNS(=O)(=O)c1cc(N)ccc1C +Cc1ccc(C)c(CNc2[nH]c(C)c(C)c2C#N)c1 +COc1ccc(CC(=O)N2CCOc3cc(N)ccc32)cc1 +CSc1nc2cc3ccccc3cc2c(=O)n1C +Cc1ccc(-c2nc(NC(=O)c3ccc(C)[nH]c3=O)n[nH]2)cc1 +CC(C)CC(=O)Nc1ccc2c(c1)OCC(C)(C)C(=O)N2 +Cc1ccoc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +O=C(NCC1CC(=O)N(c2ccc(Cl)cc2)C1)c1cccc(F)c1 +O=C(NC1CCN(C(=O)c2cnc3ccoc3c2)C1)c1ccccc1 +CC(C)C(O)C1NCCc2cc(Cl)cc(Cl)c21 +CS(=O)(=O)N1CCC(c2nc3ccccc3s2)CC1 +CCn1nnc(NC(=O)c2ccccc2Cl)n1 +c1ccc2oc(-c3cnnc(NCc4nnc5n4CCC5)n3)cc2c1 +COCCNC(=O)c1cc2c(=O)n3ccccc3nc2n1C +O=C(Nc1ccc2ncccc2c1)C1CC1(Cl)Cl +Cc1cc(C(=O)N2CCC2)cc(C)c1OCc1cccnc1 +CCCCN(CCCC)C(=O)c1cnc(C)nc1N +COC(=O)c1[nH]c(C)cc1NC(=O)c1ncn(-c2ccccc2)n1 +CCn1cc(NS(=O)(=O)c2cn[nH]c2C)cn1 +Cc1ccc(C2(Cc3sccc3C)NC(N)=NC2=O)cc1 +Cn1ccnc1SCC(=O)Nc1ccc(C#N)c(Cl)c1 +Oc1ccc(CNc2ccccn2)c2cccnc12 +Cn1cc(C(=O)OCc2cccc(Br)c2)c(=O)[nH]c1=O +Cc1ccc(NS(=O)(=O)c2cc(C(N)=O)n(C)c2)cc1F +Cc1noc(C)c1CNc1cnn(-c2ccccc2Br)c1 +O=c1[nH]c(=O)n(Cc2ccccc2)cc1Br +CCCCCC(C)NC(=O)c1cccc(-n2nnnc2C)c1 +CC(C)C(C)NC(=O)Nc1ccc(-n2cccn2)c(Cl)c1 +CSc1cc(C(=O)Nc2ccnn2C2CCCCC2)ccn1 +O=C(CCCC(=O)c1ccc(F)cc1)NC1CCCC1 +COc1ccc2cc(C3CN(Cc4nccs4)CCO3)ccc2c1 +O=C(CO)N1CCC(c2nnc(Cn3ccnc3)n2C2CC2)CC1 +CN(Cc1csc(C#CCO)c1)C(=O)c1ccno1 +Cc1cccc(C(C(=O)NCCn2nc(C)nc2C)N(C)C)c1 +CCc1cccc(CC)c1NC(=O)CSc1nnc(C2CC2)n1C +CCOC(=O)c1c(NC(=O)Cc2c(C)noc2C)sc(C)c1C +CN(CCOCC1CC1)C(=O)c1cc(F)ccc1Br +O=C(CCCNC(=O)c1ccccc1)NCc1ccccc1F +Cc1cccc(C(=O)NC(C)C(=O)N(C)Cc2ccc(C)s2)c1 +CCCCN(C)S(=O)(=O)c1cccc2c(N)cccc12 +CNC(=O)c1ccc(OC)c(NC(=O)N2CC(C)CC(C)C2)c1 +CC(C1CC1)N(C)C(=O)c1ccc2ccccc2n1 +CCOC(=O)Cn1nc(C)c(NC(=O)c2cccc(Cl)c2)c1C +Cc1cc(NC(=O)C(C)(C)C)ccc1N1CCCC1=O +NC(=O)c1cn(Cc2cccc(C(F)(F)F)c2)c(C2CC2)n1 +O=C(Nc1cccnc1)C1CSc2nccc(=O)n2C1 +CC(C)NC(=O)Nc1cccc(C(=O)Nc2ccccc2C(N)=O)c1 +CSc1ncccc1C(=O)NCc1ccc(NC(N)=O)cc1 +Cc1cccc(C)c1NC(=O)CSc1nnc(C(F)(F)F)n1N +CCN(CCC(=O)OC)C(=O)c1cc(F)ccc1Br +Cc1nc(SCC(=O)NCC(C)C)c2ccccc2n1 +CSc1ncc(C(=O)N2CCCCCC2)n1-c1ccccc1 +Cc1nnc2c(NCCCN3CCOCC3)nc3ccccc3n12 +O=S(=O)(NC1CC1)c1cccc(-c2nc(-c3ccccn3)no2)c1 +CCOc1ccccc1CNC(=O)NCC(=O)N(C)C +Cc1cccc(Cn2nc(C)c(NC(=O)c3ccncc3)c2C)c1 +CN(CC(N)=O)C(=O)c1ccnc(-n2cncn2)c1 +COC(=O)c1cc2occc2n1CC(=O)Nc1cc(C)cc(C)c1 +CCCNC(=O)c1cccc(NC(=O)N(C)Cc2ccccc2F)c1 +O=C(c1cccs1)c1cc2c(cc1Cl)OCCO2 +O=C(NCCc1nnc2ccccn12)c1ccccc1 +CCN1CCCCC1C(=O)OCc1cc(=O)n2cccc(C)c2n1 +O=C1CCCN1CCC(=O)N1CCc2cc(F)ccc2C1 +CCCCS(=O)(=O)N1CCCC(c2nnc3n2CCCCC3)C1 +O=C(NCCc1nc2ccccc2[nH]1)c1cc(Cl)c2c(c1)OCO2 +Cn1cnc(CNC(=O)NCC2CCC(c3ccccc3)CC2)n1 +Cc1cc(C(=O)Nc2ccc(NC(=O)C3CC3)cc2)c(C)n1C1CC1 +CN1C(=O)c2cc(NC(=O)c3ccco3)ccc2N2CCN=C12 +CCCc1ccc(S(=O)(=O)N2CCCC(=O)C2)cc1 +CC(=O)Nc1ccc(CC(=O)N(C)CCC(F)(F)F)cc1 +c1ccc(-c2noc(CN(Cc3ccco3)CC3CCCO3)n2)cc1 +COC(=O)C(C#N)c1nc2ccccc2nc1N(C)CC(C)C#N +Cc1cc(C(=O)NCc2ccccc2C)c2c(=O)[nH]n(C)c2n1 +O=C(NCc1csc(=O)[nH]1)c1cc(C2CCCCC2)n[nH]1 +CN(c1ccc(C(=O)N2CCc3ccccc32)cc1)S(C)(=O)=O +COc1ccc(COC(=O)c2ccc(S(C)=O)cc2)cc1 +O=C1Cc2ccccc2C(c2cccc(Br)c2)N1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3cccc(Cl)c3F)c2)n1 +CCOc1cccc(C(=O)Nc2cc(N)ccc2OC)c1 +CC(C)C(=O)OCc1cc(=O)n2nc(C(C)C)sc2n1 +CCN1CC(C(=O)N2CCN(c3nccs3)CC2)CC1=O +CC(C)NC(=O)CNC(=O)c1cc2c(F)cccc2n1C +C#CCN1CCN(CC(=O)N(CC)C(C)c2ccc(F)cc2)CC1 +CCOc1ncccc1C(=O)Nc1ccc2c(c1)OCCO2 +CCn1cc(-c2n[nH]c(=O)n2CCc2ccccc2)cn1 +C=CCN1C(=O)COc2ccc(NC(=O)CCC)cc21 +NC(=O)c1cc(Cl)ccc1NCC(=O)N1CCNC(=O)C1 +CNC(=O)c1ccc(C)c(S(=O)(=O)Nc2ccccc2OC)c1 +O=C(CSc1ccccc1F)Nc1ccnn1Cc1cccs1 +CCCCNC(=O)N(Cc1ccco1)CC1CCCO1 +CCCCNC(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1 +CC(=O)NCC(O)c1ccc2c(c1)[nH]c1ccccc12 +COc1ccc(OC)c(CCC(=O)N(C)Cc2cccc(C#N)c2)c1 +CC(C(=O)Nc1ccc(F)c(Cl)c1)n1ncc2ccccc2c1=O +Cc1ccc(CN2CC3CN(Cc4ccncc4)CCN3C2=O)cc1 +Cc1ccoc1C(=O)N(C)Cc1cc(-c2cccs2)n[nH]1 +O=C(CN1CCOCC1)N1CCN(c2ncnc3ccsc23)CC1 +Cc1cccc(NC(=O)CSc2nc3ccccc3s2)n1 +CC(=O)N1CCN(C(=O)c2ccccc2F)CC1 +Cc1ccc(C)c(CC(=O)NCc2ccc(=O)[nH]c2)c1 +CCNC(=O)Nc1cccc(NC(=O)C2CCOC2)c1 +CC1N(CC2CC2)C(=O)COC12CCN(C(=O)N(C)C)CC2 +COC(CNS(=O)(=O)N1CC(C)CC(C)C1)c1ccccc1 +COc1ncccc1C(=O)NCc1n[nH]c(=O)c2ccccc12 +CCOc1ccc(C2C(C(N)=O)=C(C)OC(N)=C2C(N)=O)cc1 +Cc1nn(C)c2ncc(C(=O)N(C)c3cccc4ncccc34)cc12 +NC(c1ccc2c(c1)CCCC(=O)N2)C(F)(F)F +CC(NC(=O)NCc1ccc(CS(N)(=O)=O)cc1)c1ccncc1 +O=C(NCC1COCCO1)Nc1ccccc1-c1cccs1 +C=CCNC(=O)c1ccc(CN2CCOCC2)cc1 +Cc1noc(-c2ccc(O)cc2O)c1-c1ccc2c(c1)OCCCO2 +Cn1cccc1C(=O)N1CCCC2(CC(Nc3cnccn3)CO2)C1 +O=C(c1cc(F)cc(F)c1)N1CCC(c2cccnc2)CC1 +COc1ccccc1C1CC1C(=O)N(C)Cc1cccc(C(N)=O)c1 +CCCC(C)NS(=O)(=O)c1c(C)ccc(N)c1C +Cc1nc(SCC(=O)N(C(C)C)C2CCCC2)oc1C +CC(C)Cc1noc(CN2CC(C)OC(c3ccsc3)C2)n1 +O=C(NCc1ccc(F)cc1)c1ccc(NC(=O)C2CC2)cc1 +O=C(NC1CCc2c(F)cccc21)c1csnn1 +CCn1c(SCc2ccccc2F)nnc1-c1ccccn1 +Cc1nnc(SCc2cn3cc(Cl)ccc3n2)s1 +Cn1c(=O)c(N2CCC(C(=O)N3CCCC3)CC2)nc2ccccc21 +OC(c1ccccc1)C1NCCc2ccc(Cl)c(F)c21 +CC(=O)Nc1ccc(NC(C)C(=O)NCCc2ccc(F)cc2)cc1 +CCSc1nc(C)cc(C(=O)Nc2ccc(C(N)=O)cc2)n1 +CNc1snc(C)c1C(=O)NC1CCN(C(C)=O)CC1 +COCCNC(=O)Nc1cccc(C)c1C(=O)N1CCCC1 +Cc1ccc(C(C)NC(=O)N(CC(O)c2ccc(F)cc2)C2CC2)o1 +CCc1cc(NCc2ccc(C(=O)N3CCCC3)cc2)n2nccc2n1 +Cc1ccc(S(=O)(=O)Oc2cccc(C(=O)NC3CC3)c2)cc1C +CCCCn1nc(-c2cccs2)cc(C(C)(C)O)c1=O +NC(=O)c1ccccc1NCC(=O)c1ccc(F)cc1 +Cc1noc(NC(=O)COc2ccc(C(N)=O)cc2)n1 +CCOc1ccnc(N2CCN(C(=O)c3sc(C)nc3C)CC2)n1 +O=C1CCc2cc(S(=O)(=O)NCc3ccccc3F)ccc2N1 +CCC(NC(=O)c1ccc(=O)[nH]c1)c1cccs1 +CCOC(=O)Cc1ccccc1NC(=O)Cn1nc(C)c(Cl)c1C +CC(=O)c1cccc(NC(=O)C(C)Oc2ccc(C#N)cc2)c1 +CC(C)n1c(=O)[nH]c2cc(-c3noc(C4CCCC4)n3)ccc21 +CCCCn1c(SC(C)C(=O)NC2CCCCC2)n[nH]c1=O +CC(C)CC(=O)Nc1ccc(NC(=O)NC(C)C(C)CO)cc1 +CC1CN(C(=O)CCCOc2cccnc2)c2ccccc2S1 +COc1ccc2c(c1OC)CN1CCc3cc4c(cc3C1=C2)OCO4 +Cn1cccc1C1CCCCN1C(=O)c1cnc(C2CCCO2)s1 +COc1ccccc1Nc1ccc(S(=O)(=O)N2CCOCC2)cn1 +CN(Cc1nc(-c2cccs2)no1)C(=O)C1CCCC1 +CN(C(=O)CNC(=O)OC(C)(C)C)c1ccc(F)cc1 +CC(=O)NCc1ccc(C(=O)COC(=O)c2sccc2C)s1 +COCCCNC(=O)c1nnc(-c2oc3ccc(C)cc3c2C)o1 +COc1ccc(C=c2sc(=CC(=O)c3ccco3)[nH]c2=O)cc1O +CNc1cc(-c2ccc(OC)cc2Cl)nc(C)n1 +O=C(Cn1c(=O)oc2cc(Cl)ccc21)Nc1ccccc1F +CCn1c(SCC(=O)C2=NC=CC2)nnc1-c1cccc(OC)c1 +O=C(COc1ccccc1F)Nc1cc(N2CCCCC2)ncn1 +CCCC(=O)Nc1ccc(-n2cnc(C(=O)NCC)c2)nc1 +O=C(Nc1ccc2oc(C3CC3)nc2c1)N1CCOCC1 +CC(=O)N1CCC(C(=O)Nc2cc(C)ccc2C)CC1 +O=C(C1CC1c1ccc(F)cc1)N1CCC(Nc2cccnn2)CC1 +COC(=O)C(c1cccc(C#N)c1)N(C)Cc1nc(C)cs1 +CCCn1ccnc1SCC(=O)Nc1nnc(-c2ccccc2)o1 +COc1ccc(-c2nc3ccccc3n2CCC#N)cc1N +Cc1ccn2cc(C(=O)NC3CCc4ccccc43)nc2c1 +COc1ccc(C(C)NC(=O)CCc2nc(C(C)(C)C)no2)cc1F +Cc1cnc(C(=O)NCc2ccccc2OC(F)(F)F)cn1 +Cc1ccc(NC(=O)Cc2noc3c(N)cc(C)cc23)nc1 +COc1cccc(OCC2CCCN(S(C)(=O)=O)C2)c1 +CCOc1cc(OC)cc2c1CCNC2c1cnccn1 +O=C(NCCC1=CCCCC1)c1cn(CC2CCCO2)nn1 +CCn1nccc1C(=O)NC(C)c1cc(OC)ccc1OC +O=C(Nc1ccccc1-n1cnnn1)c1ccc(OC(F)F)cc1 +Fc1ccc(C2(CNc3ncnc4ncccc34)CC2)c(F)c1 +Cn1nnnc1SCC(=O)C(C#N)c1nc2ccccc2s1 +COCCN1C(=O)CCCC12CCCN(C(=O)c1cc(C)n[nH]1)C2 +COc1c(Br)c2c(c(OC)c1OC)C(C)(C)CNC2 +CCn1nccc1C(=O)Nc1nc2c(OC)cccc2s1 +COCCC(=O)Nc1ccc(C(=O)OC(C)(C)C)c(C)c1 +Cc1nc(CSc2nnc(C)o2)n(CC(F)(F)F)n1 +CCN(C)S(=O)(=O)c1ccc(NC(C)=O)c2ccccc12 +Cc1ccnc(Nc2nc(CC(=O)NCc3cccnc3)cs2)c1 +CCN(C(=O)c1ccnc(C)n1)C1CCCCC1C +CC(Cc1cccc(Cl)c1)NC(=O)C1CC(=O)N(C)C1 +COCCOc1ccc(C(=O)Nc2ccccc2F)cc1 +CC(C)(C)c1nnc(NCc2ccc(Oc3cnccn3)cc2)o1 +O=S(=O)(c1cccnc1)N1CCCC1C1CCCC1 +Cn1c(SCC(C#N)CCC#N)nnc1-c1ccc(F)cc1 +CCn1nnc(-c2ccccc2NS(=O)(=O)c2ccccc2)n1 +CC(CNC(=O)c1n[nH]c2ccccc12)N1CCOCC1 +CCc1noc(CC)c1CNS(=O)(=O)c1ccccc1OC +Cn1ncc2c(NCc3cnn(Cc4ccccc4)c3)ncnc21 +Cc1cc(NS(=O)(=O)c2ccc(F)cc2)ccc1N1CCCC1=O +O=C(N1CC2CCC1C2)C1(c2cccc(Cl)c2)CCOCC1 +CCC(C)N(CC(=O)NC(C)C)Cc1nc2ccccc2c(=O)[nH]1 +COc1ncccc1C(=O)N1CCN(c2c(C)n[nH]c2C)CC1 +Cc1cnc(C(C)CNC(=O)Nc2cccnn2)s1 +CCN1CC(C(=O)NCCN(C)c2ccccc2)CC1=O +Cc1cc(-c2ccccc2)nc2cc(C(=O)NCc3cccs3)nn12 +COC(=O)Cc1nccc2c(F)c(F)c(F)cc12 +COCCOc1cc(C)ccc1NC(=O)NCc1ccncc1 +COc1ccc(S(=O)(=O)NCc2ccco2)cc1C(C)C +Cc1nnc(NC(=O)Cc2cc(-c3ccc(Cl)cc3)on2)s1 +CC(=O)N1CCc2oc(N)c(C(=O)c3ccccn3)c2C1 +COCCCC(=O)Nc1ccccc1S(=O)(=O)N1CCOCC1 +CC(=O)N1CCN(CC(=O)c2ccc3c(c2)CCC3)CC1 +CC1CCCN(S(=O)(=O)c2cc(Br)ccc2N)C1C +Cc1cc(N)ccc1NC(=O)CCOC1CCC(C)CC1 +Cc1cc(OCC(=O)NC(C)(C)C(N)=O)c(C(C)C)cc1Cl +C#CCN1C(=O)C2(CCN(C(C)=O)CC2)Nc2cc(C)ccc21 +COC(=O)c1ccccc1N(C)C(=O)c1cccc(-n2cccn2)c1 +O=C(NC1CCc2cc(Cl)ccc21)c1ccco1 +CC1CC1CNC(=O)c1sccc1NS(C)(=O)=O +CN(CCc1ccccn1)C(=O)COc1ccc2ccc(=O)oc2c1 +Cc1ccc2nc(C)cc(C(=O)Nc3nncs3)c2c1 +Cc1cc(C)c(C(=O)NCc2ccccc2)c(=O)[nH]1 +COC(=O)Cn1c(=O)cc(C(F)(F)F)c2c(C)noc21 +CS(=O)(=O)NC1(c2ccc(Br)cc2)CC1 +Cc1cc(C(C)(C)C)ccc1C(=O)Cn1cc(N)cn1 +CCCNC(=O)C1CCN(S(=O)(=O)c2cc(C)ccc2F)CC1 +O=C1NCCCC1(c1ccccc1)c1ccccc1 +CCNC(=O)c1csc(Nc2cccc(Cl)c2)n1 +COC(=O)NCC(=O)NCC(C)N(C)c1ccccc1 +COc1ccc(OCCCn2nncc2CO)cc1 +Clc1ccccc1-c1nnc(CN2CCc3ccccc3C2)o1 +Nc1ccc(C(=O)N2CCC(c3ccccc3)C2)cc1 +Cc1cc(C)c(C#N)c(SCc2nccn2CC(F)(F)F)n1 +Cc1ccc(C(=O)CC2(O)C(=O)N(CCCC#N)c3ccccc32)o1 +Cc1nc(-c2cccc(-c3nc(C4CC4)no3)c2)n[nH]1 +O=C1NCC2CN(c3nccc(C(F)(F)F)n3)CCN2C1=O +CC(C)NC(=O)CSc1nnc(-c2cccs2)o1 +COC1CCN(C(=O)C2CCOCC2)CC1Cc1cccc(C)c1 +Cn1ncc(C(=O)NCc2nc(-c3ccncc3)no2)c1-n1cccc1 +CCN(CC(=O)NC(C)C(=O)OC)c1ccccc1 +CCOc1ccc(CC(=O)Nc2ccc3nc(C)oc3c2)cc1 +COCC(C)(O)CNC(=O)Nc1ccc(F)cc1 +COCc1ccccc1C(=O)N(C)CC(O)COC +COc1ccc(NC(=O)CCCN2CCCC2=O)c(N)c1 +N#Cc1cc(F)ccc1Cn1cnc(C#N)c1C#N +CCc1c(C(=O)NC2CC2c2ccccc2OC)[nH]c(C)c1C(C)=O +NC(c1ccncc1)c1c(F)ccc2cccnc12 +Cc1noc(C)c1Cn1nnc(CO)c1-c1ccccc1F +CNC(=O)c1cccc(NC(=O)NC2CCc3ccccc3C2)c1 +CC(C)c1nnc(SCC(=O)N2CCN(C)CC2)n1N +CC(C)N(C(=O)C1CCC(NC(=O)C2CCCC2)CC1)C(C)C +COCCN(CCC#N)Cc1cc(N)ccc1Cl +CCOCC(=O)Nc1cccc(C(=O)NC2CC2)c1 +COCCOc1ccccc1C(=O)NCc1cccs1 +O=C(c1csnn1)N1CCN(Cc2ccc3c(c2)OCCO3)CC1 +COCc1ccccc1C(=O)NCC(C)(C)NS(C)(=O)=O +CC(=O)N1CCC2(CC1)CCN(S(=O)(=O)c1ccccc1)C2 +COC(=O)c1ccc(F)cc1NC(=O)c1cnccn1 +CCC(C)c1nnc(C2(c3ccc(OC)cc3)CCOCC2)o1 +COCC(=O)N(C)CC(=O)Nc1ccc(C(C)=O)c(C)c1 +c1csc(-c2nn3c(C4COc5ccccc5O4)nnc3s2)c1 +O=C(NCCc1c(Cl)cccc1Cl)c1ccc(=O)[nH]c1 +Brc1ccccc1-c1nnc(CNCCc2ccco2)o1 +C1CC(c2noc(C3CC3)n2)N(Cc2nnc(C3CC3)o2)C1 +Cc1cccc(C2NCCc3c(Cl)cc(Cl)cc32)n1 +CCN(CC(O)COc1ccccc1)c1ccccc1 +Cc1cnc(C(=O)Nc2ccccc2N2CCc3ccccc3C2)cn1 +CNc1nnc(-c2scnc2C(C)(C)C)s1 +CCCNC(=O)NCc1noc(-c2ccsc2)n1 +CCn1ncc(C(=O)N(C)CCCc2ccccc2)c1C(F)(F)F +COc1ccc(NS(=O)(=O)Cc2ccc(F)cc2)cc1 +CCC(C)c1ccc(S(=O)(=O)NCc2ccncc2)cc1 +NC(=O)CC1CCN(C(=O)C2COc3ccc(F)cc3C2)CC1 +CCCS(=O)(=O)NCC(C)(C)c1ccccc1OC +CC(C)c1nc(CNc2cnn(-c3ccccc3)c2)cs1 +COCCNC(=O)N1CCN(c2cccc(OC)c2)CC1 +COc1cccc(NC(=O)Cn2cnc3oc(C)c(C)c3c2=O)c1 +Cc1cc(F)ccc1CCNC(=O)c1cnc2sccn2c1=O +CN(C)c1ccc(C(=O)Nc2cnn(-c3ccccc3F)c2)cc1 +Nc1nonc1-c1noc(NCc2cccc(C(F)(F)F)c2)n1 +COCCn1cccc(C(N)c2ccc(C)cc2C)c1=O +C=CCOC(=O)COc1ccc2c(CC)cc(=O)oc2c1 +Cc1cccnc1CNC(=O)c1cn(Cc2ccccc2Cl)nn1 +Nc1cc(C(=O)CCC(=O)N2CCCC2)ccc1F +CCOC(=O)c1sc2c(F)c(F)c(F)cc2c1C +CC(O)CNC(=O)C1(c2cccc(Br)c2)CC1 +CCC1c2ccccc2CCN1C(=O)CN1CCCOC1=O +O=c1ccc(C2NCCc3c2ccc(Cl)c3Cl)n[nH]1 +Cc1ccc(C(=O)NC(C)c2ccc(S(N)(=O)=O)cc2)cn1 +CC(C)(C)OC(=O)N1CCC(C(=O)Nc2nc3ccccc3s2)C1 +C=CCN(Cc1noc(C(C)C)n1)S(=O)(=O)c1cccs1 +O=C(NCc1ccncc1)c1cc2cc(Cl)ccc2[nH]1 +CCOC(=O)C1(N)CC1c1ccc(OC)c(OCC)c1 +CCCCS(=O)(=O)N1CCNC(=O)C1c1ccccc1 +c1cncc(-c2ncc(CN3CCOC4CCCCC43)s2)c1 +O=C(c1ccc(Oc2cccnc2)cc1)N1CCC2(CC1)OCCO2 +Cc1nn(COc2cccc(F)c2)c(C)c1NC(=O)c1cccnc1 +Cc1nccn1-c1ncccc1NC(=O)CCC(=O)c1ccccc1 +CCc1cc(N2CCN(C(=O)C3CCCN(C(N)=O)C3)CC2)ncn1 +CC1CCN(C(=O)c2ccc(NCc3ccco3)nc2)CC1 +c1cnc(Oc2ccc(CN3CCOCC34CCC4)cc2)cn1 +Oc1ccc2c(c1F)C(C=Cc1ccco1)NCC2 +COC(=O)c1ccc(OCc2ccccc2F)nc1 +Cc1ccc(C(=O)C(C)Sc2nncn2C(C)C)cc1 +CN1C(CO)C(O)C(O)C1n1cnc2c(N)ncnc21 +CCCc1ccc(-c2nc3n(c2CO)CCS3)cc1 +Cc1nc(C)c(C(C)C)c(N2CCN(C(=O)C3CCCC3)CC2)n1 +CC(C)(C)NC(=O)c1cccc(NCC(=O)NCc2cccs2)c1 +Cc1cccc(NC(=O)Cn2cc(-c3ccccc3)ncc2=O)n1 +COC1CCN(c2ncccn2)C1Cc1ccccc1 +COc1ccc(NC(=O)CCn2cc(C)cn2)cc1Cl +Cn1cc(C(=O)NC2CCc3c(O)cccc32)c(C(C)(C)C)n1 +O=C(c1cnc(C2CCCO2)s1)N(Cc1ccc(F)cc1)C1CC1 +Cc1ccn2c(=NC(=O)CCCNC(=O)OC(C)(C)C)[nH]nc2c1 +Cc1cc(-c2nnc(NCc3cccnc3)o2)c(C)o1 +COc1ccc(NC(=O)c2n[nH]c3ccc(C)cc23)cc1 +COc1cc(C(=O)OC2CCOC2=O)ccc1OCc1ccccc1 +Cc1cc(=O)c(C2NCCc3cc(F)cc(F)c32)c[nH]1 +N#CC1(C(=O)Nc2cccc3[nH]cnc23)CCCCC1 +COc1ccc(CCn2cnc3c(cnn3-c3ccccc3)c2=O)cc1 +CNC(=O)COc1ccc(C(=O)c2ccc(Cl)cc2)cc1 +CCOC(=O)c1c(-c2c(F)cc(F)cc2F)n[nH]c1N +CC(C)OC(=O)c1ccc(OCc2nnc(C(C)(C)C)o2)cc1 +CCS(=O)(=O)NCC(=O)Nc1ccc(-n2cccn2)cc1 +O=C(CC1C=CCC1)Nc1ccc(F)c(Cl)c1 +O=C(c1ccc(OCC(F)F)nc1)N(c1ccccn1)C1CCCC1 +CCCn1cc(NC(=O)c2cc(-c3ccccc3)on2)cn1 +COc1cc(OC)c(NC(=O)c2ccc(C(=O)N(C)C)cc2)cc1F +CC(NC(=O)Cn1c(=O)[nH]c2ccccc21)C1CCCO1 +COc1ccc(NC(=O)CN2CCOCC2C2CC2)cc1 +Cc1ccccc1-c1nnc2[nH]c(=O)n(C)c(=O)c2n1 +NC(=O)CSc1ccc(NC(=O)c2ccco2)nn1 +Cc1nn(C)c(C)c1NC(=O)CNc1cc(F)c(F)cc1F +O=C(c1scnc1C1CC1)N1CCN(c2nccs2)CC1 +Cc1ccnc(NC(=O)COc2ccc(C)cc2Br)c1 +Cn1cc(-c2nc(C(=O)NC3CC4CC3C3CCCC43)cs2)cn1 +Cc1cc(Cc2ccccc2Br)ncn1 +CCOC(=O)C(C)NC(=O)C(C)Sc1nncs1 +O=C(Nc1cc(N2CCOCC2)ncn1)c1ccco1 +Cc1nnc(NC(=O)c2ccc(-n3cccn3)nn2)s1 +CCOc1ccc(NC(=O)CCCn2cncn2)c(C)c1 +COc1cccc(Cn2cc(-c3ccc(C#CCO)cc3)nn2)c1 +Cn1ccc(NC(=O)Cc2coc3ccc4ccccc4c23)n1 +CCCCN(C)C(=O)c1ccc2onc(-c3csc(C)n3)c2c1 +Fc1cc(CNCCC(F)(F)F)ccc1OC(F)F +COc1ncncc1NC(=O)NCc1cccc(-c2n[nH]c(C)n2)c1 +N#Cc1c(NC(=O)Cc2cccs2)sc2c1CCCC2 +CC(C)c1cnc(CNC(=O)c2ccc(Br)cc2)o1 +CC(C)CCN(C)C(=O)NCc1ccc(N2CCCC2=O)cc1 +Cc1ccccc1C1=Nn2c(nnc2-c2n[nH]c3c2CCC3)SC1 +CCCCc1nnc(NC(=O)c2cccc3cccnc23)s1 +CC(=O)NCc1ccc(C(=O)NCCc2ccc(F)cc2)cc1 +O=S(=O)(CCc1ccccc1)NCC1(O)CCOc2ccccc21 +CN(Cc1ccc2c(c1)OCO2)C(=O)NCc1ncn(C)n1 +Cc1cccn2c(CN3CCC(n4cccn4)CC3)cnc12 +C=CCN(CCO)C(=O)NC(CC)c1cc(F)ccc1F +CC1CCCC1NC(=O)NCCNC(=O)C1CCCCC1 +COCC(=O)NCc1ccc(NC(=O)c2ccco2)cc1 +Cn1cc(C(=O)N2CCC(NC(=O)Nc3ccccc3)CC2)cn1 +C#CCNC(=O)N1CCN(CC(=O)NC(C)CC)CC1 +CCCS(=O)(=O)c1ccccc1NC(=O)CC +CCCS(=O)(=O)N1CCCN(c2cc(C(=O)OC)ccn2)CC1 +CC(C)(C)c1ncc(NC(=O)NC2CC=CC2)cn1 +c1cnc(-n2cncn2)c(CNCc2cccc3c2OCCCO3)c1 +N#Cc1ccc(CN2CCNC(=O)C2c2cccs2)cc1 +O=C(c1cccs1)N1CCc2cc(-c3ccno3)ccc21 +COc1ccc(OC)c(CN(C(=O)c2ccc[nH]2)C2CC2)c1 +CC1(C)CC(=O)c2cc(Br)cc(N)c2O1 +CNC(=O)c1cccc(OS(=O)(=O)c2ccc(Cl)cc2C)c1 +O=C(Nc1ccc(CN2CCOCC2)c(Cl)c1)C1CC=CC1 +CC(NC(=O)CCC(=O)c1ccc(F)c(F)c1)c1cnn(C)c1 +COc1cccc2sc(NC(=O)c3ccc4[nH]cnc4c3)nc12 +CC(=O)C1C(c2ccccc2)n2ncnc2NC1(C)O +CCNC(=O)c1cc(-c2cccc(OCC3CCCO3)c2)nc(N)n1 +O=C(OCC(=O)N1CCc2ccccc21)C1COc2ccccc2O1 +Cc1cc(CO)ccc1Oc1ccc(C(N)=O)cc1 +Cn1c(C(C)(C)C)nc2cc(NC(=O)c3ccon3)ccc21 +CC(NS(=O)(=O)c1cnn(C)c1)c1ccc(OC(F)(F)F)cc1 +CCc1c(C)nn(C(=O)c2cc(OC)c(OC)c(OC)c2)c1C +CC(=O)c1cccc(NC(=O)COc2cccc3c2OC(C)(C)C3)c1 +Cn1c(C(=O)Nc2ccc(CN3CCOCC3)cc2)cc2ccccc21 +N#Cc1cc(F)ccc1N1CCC(CC(=O)N2CCCC2)CC1 +COc1ccccc1COc1cccc(NC(=O)c2cc[nH]n2)c1C +C=CCNC(=O)CCNC(=O)c1ccc(F)cc1F +CCN(Cc1ccncc1)C(=O)c1cccc(OC)c1 +CCOCc1cccc(CNC(=O)Nc2ccncc2)c1 +CCOc1cc(C#N)ccc1OCC(=O)N(C)CC1CC1 +CN(C(=O)c1c[nH]c2cccc(F)c12)c1ccc(F)cc1 +Cc1ccc(NS(=O)(=O)c2ccccc2)c(=O)n1CC(=O)N(C)C +O=C(c1ccccc1-c1nc2ccccc2[nH]1)N1CCOCC1 +CCOc1c(C)cc(C)cc1-c1cc(C(=O)OC)n(CCO)n1 +CC1CC(c2ccccc2)C(C)N1S(C)(=O)=O +Cc1cc(C)n(C(C)C(=O)Nc2ccc(F)cc2F)n1 +NC(=O)c1ccc(OCC(=O)Nc2ccc(Br)cc2)cc1 +CCCCNC(=O)Nc1ccc2c(c1)OCC(=O)N2 +COc1ccccc1CNC(=O)c1sc(-c2ccncc2)nc1C +Cc1cnc(CCNC(=O)NCC(O)C2CC2)s1 +CC(C)(C)c1nnc(SCC(=O)Nc2cc(F)ccc2F)n1N +COCn1cnc2c(nnn2-c2ccccc2)c1=O +CN(Cc1ccn[nH]1)C(=O)COc1ccc(F)cc1 +CS(=O)c1ccc(CNC(=O)Nc2nc(C3CC3)cs2)cc1 +COC(=O)c1sc(C(N)c2cccc(O)c2)nc1C +CCC(CC)n1nc(C)cc1NC(=O)CCn1cnc2ccccc21 +O=C(Nc1cccc(F)c1)N1CCC(CO)(Nc2ccccc2)CC1 +Cc1sc2ncnc(N3CCc4nnc(C(C)C)n4CC3)c2c1C +Cc1nn(C)c(C)c1CCNC(=O)NC1CC(C)(C)OC1(C)C +O=C(NCC1(O)CCOc2ccccc21)Nc1cccc(Cl)c1 +c1ccc(-n2cc(NCc3cnc(-c4cccnc4)s3)cn2)cc1 +Cc1ccccc1OCC(=O)Nc1cc(N2CCCC2)ncn1 +O=S(=O)(Cc1c(F)cccc1Cl)N1CCc2ccccc2C1 +CC(C)(C)c1nc(-c2ccc(Cl)c(F)c2)c(N)n1N +O=C(CSc1nnc(-c2cccc3ccccc23)o1)N1CCCC1 +CCOC(=O)c1cc2cccc(Br)c2cn1 +CC(OCC1CC1)C(=O)NCc1ccc(S(N)(=O)=O)cc1 +O=C(Nc1ccsc1-c1nnc(C2CC2)o1)c1ccccc1 +Cc1noc(-c2cccc(OCC(=O)Nc3cccc(C)c3C)c2)n1 +Cn1c(SCC(C#N)CCC#N)nnc1-c1ccco1 +O=C(NCc1cccc(O)c1)c1ccc2c(c1)CCC2 +C#CCn1nc(CO)cc1-c1ccc(NC(C)=O)cc1 +Fc1cc(F)cc(-c2[nH]ncc2-c2nnnn2-c2ccccc2)c1 +Cc1ccccc1COC1CCN(C(=O)C2CCC(C)O2)CC1 +O=C(NCc1ccc(F)cc1)C(Cc1ccccc1)n1cnnn1 +Cc1nnc2sc(-c3ccccc3NC(=O)c3cccnc3)nn12 +Cc1cc(C)nc(NC(=O)c2csc3c2CCCC3)n1 +COCCCS(=O)(=O)N1CCN(C2CCCCC2O)CC1 +CC(NC(=O)C1CCCN1C(=O)OCC(F)(F)F)c1ccncc1 +COc1ccc(NC(=O)NCC(C)CC(C)O)cc1OC +Cc1cc(CC(=O)NC(c2ccc3c(c2)OCCO3)C(C)C)no1 +Cn1c(CNC(=O)c2ncoc2-c2cccs2)nc2ccccc21 +Cn1c(CCCNc2ncccc2C#N)nc2ccccc21 +Cc1nn(C)c(Oc2ccccc2)c1CNCCc1cnn(C)c1 +Cn1c(CCCNC(=O)c2cnc3[nH]ccc3c2)nc2ccccc21 +CCOC(=O)c1[nH]c(C)c(CCC(=O)Nc2c(C)cccc2C)c1C +CNS(=O)(=O)c1cccc(S(=O)(=O)N(C)CC(C)C#N)c1 +Cc1nn(-c2ccc(NC(=O)C3CCC(=O)N3)cn2)c(C)c1Cl +CC(C)CC1CN(C(=O)c2n[nH]c3ccccc23)CCC1(C)O +O=C(Nc1ccccc1C(=O)N1CCOCC1)NC1CCCCCC1 +CC(C)Oc1ccc(-c2csc3nc(CO)cn23)cc1 +Cc1ccc(Br)cc1NCCN1CCOCC1 +COC1CCCC(OC(=O)c2cnn(CC(C)C)c2C2CC2)C1 +COc1cccc(-c2nnn(CC(=O)Nc3cccc(Cl)c3)n2)c1 +O=C(NCCn1ccc(C(F)(F)F)n1)c1ccncc1 +CCNC(=O)Nc1nc(C)c2c(n1)CC(C)(C)CC2=O +Cc1nc(NC(=O)COc2ccc(N3CCCC3=O)cc2)sc1C +Cc1csc(SCC(=O)N(C)Cc2ccc(C)o2)n1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1cc2c([nH]c1=O)CCCC2 +COc1ccc2cc(C(=O)OC3CC(C)OC3=O)c(C)nc2c1 +Cc1nc(C(C)C)sc1C(=O)Nc1cn[nH]c1 +CC1(C(=O)N2CCN(CCOc3ccccc3)CC2)CCCCO1 +O=C(Nc1cnn(C2CCOC2)c1)c1cccs1 +CC(C)(C)OC(=O)NCC1CCC(C(=O)NCC(F)(F)F)CC1 +COc1cc(COC(=O)Cn2ncc3ccccc3c2=O)ccc1C +CCOC(=O)c1cc(S(=O)(=O)Nc2ccc(C)cc2)cn1C +O=C(NCC(F)(F)F)c1ccc(N2CCOCC2)nn1 +Cc1c[nH]nc1C1(C)CN(c2cnccn2)CCO1 +CCOC(=O)c1sc2nc(C)nc(N)c2c1C +Cc1ccnc(Nc2ncnc(NCCc3cccs3)c2N)c1 +CC1CCCN(C(=O)Nc2cccc3c2OCCO3)C1CO +Cc1c(C(=O)NCc2nc3ccccc3s2)cnn1-c1ccncc1 +c1ccc(C2CCCN2c2ncnc3sccc23)nc1 +CC(C)(C)c1cccc(OCC(=O)N2CCC(=O)CC2)c1 +Cc1ccc(-c2noc(CSc3nnc(C4CC4)n3C)n2)cc1 +C=CCN(CC=C)C(=O)CCc1c(C)nc2nc(N)nn2c1C +O=C(COC(=O)c1cccc(O)c1)NC1CCCCCC1 +CCC(C)C(NC(=O)Cc1ccc(Cl)cc1Cl)C(N)=O +CC(C)NC(=O)c1cc(S(=O)(=O)N(C)C(C)C)ccc1Cl +CCc1nc(C2CCCN2c2ncnc3sc(C)c(C)c23)no1 +CC(C)Cn1c(=O)c(C(=O)NC2CCCCCC2)nc2cccnc21 +COc1cccc(C(N)=O)c1OCC(=O)Nc1cccc(Cl)c1 +CCOC(=O)C1CCN(C(=O)c2ccc3[nH]cnc3c2)CC1 +O=C(OCCCn1c(=O)[nH]c2ccccc21)c1n[nH]c2ccccc12 +Cc1ncc(C(=O)N2CCN(Cc3ccccc3C#N)CC2)c(=O)[nH]1 +CC(C)OCCCN1C(=O)c2ccccc2S1(=O)=O +CN(C)c1ccccc1C#CCNC(=O)c1ccc2[nH]ccc2c1 +COc1ccccc1N1CCN(c2nc3c(s2)c(C)nn3C)CC1 +CCC(OC)C(=O)NCc1cccnc1-n1cccn1 +C=CCOc1ccc(C(=O)OC(C)c2nc(C)no2)cc1 +Cc1oc(C(C)C)nc1C(=O)N(C)CC(=O)N1CCOCC1 +NC(=O)c1ccc2oc(-c3ccc(Br)cc3F)nc2c1 +CCn1nc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)cc1C +COc1cccc(C(=O)NCCC(=O)Nc2cccc(F)c2)c1 +Cc1ccc2ncc(C(=O)Nc3ccn(CC(F)F)n3)n2c1 +CNC(=O)c1cccc(NCC(=O)Nc2cccc(OC(C)C)c2)c1 +COc1c(C)cnc(CSc2nnnn2C)c1C +COCCSc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 +Cc1ccncc1NC(=O)CCC(=O)c1ccc(F)c(F)c1 +CCC(C#N)NC(=O)CNc1ccccc1Cl +Cc1ccc(-c2ccc(CN3CCOC(c4cnn(C)c4)C3)o2)cc1 +COc1cc(NC(=O)C2CC(=O)N(C)C2)cc(OC)c1 +Cc1cccc(NC(=O)NCCNC(=O)c2ccc(F)cc2)c1C +Cc1cc(NC(=O)c2nn(C)c3c2COc2ccccc2-3)no1 +CCC(O)CN1CCN(C(=O)c2ccc(C)c(OC)c2)CC1 +O=C(C1CC1)N(Cc1cccnc1)c1ccccc1 +COc1ccc(-c2nc3ncc(N)cn3n2)cc1OC +Nc1[nH]nc(-c2cc(F)ccc2F)c1Br +CCC1(O)CCN(C(=O)c2cc(C(F)(F)F)ccc2C)CC1O +O=C(NCc1cccs1)c1cccc2[nH]ccc12 +N#CC(C(=O)c1cc(F)c(F)cc1Cl)c1ccccn1 +CCC(C)c1ccccc1NC(=O)c1ccc(N)nn1 +COc1cc(C#N)ccc1OCC(=O)NCc1nc(C)sc1C +CC(=O)NC1CCN(c2cc(-c3ccccc3F)nc3ccnn23)C1 +CC(=O)N1CCC(C(=O)Nc2c[nH]cc(Br)c2=O)C1 +COc1cc(C(N)C(=O)NC(C)C)c(OC)cc1C +O=C(C1CCC1)N1CC2CCCN2c2ncccc21 +CCCC(=O)NCC1CCCN(C(=O)c2ccc(OC)cc2)C1 +CC(=O)c1cnc(NCc2cc(C(C)C)no2)nc1C +CC(CNc1ncn[nH]1)Cc1ccc2c(c1)OCO2 +CCN(C(=O)c1ccc(O)cc1)c1ccccc1C +CC1Cc2ccccc2N1C(=O)Cn1cc(C(F)(F)F)ccc1=O +CNC(=O)c1ccc(NC(=O)N2CCCC3CCCC32)cc1Cl +COc1ccc(C(=O)Nc2cc(C#N)ccc2Cl)cc1 +C#CCN1CCC(C(=O)NC(C)COc2ccc(F)cc2)CC1 +COCCOCC(=O)N1CCN(c2ncc(Cl)cc2Cl)CC1 +O=C(c1ccccc1Cl)N1CCC(O)(C(F)(F)F)CC1 +Cc1ccccc1CN(C)C(=O)Cn1nnc2ccccc21 +Cn1c(COc2ccccc2-c2nccs2)nnc1C1CCC1 +Cc1nc(NCC2(C)CCCO2)cc(-c2ccc3c(c2)ncn3C)n1 +c1cncc(CCNCc2ccccc2OC2CCCC2)c1 +Cc1cc(NC(=O)NC(C)C(=O)NCC(F)(F)F)no1 +Cc1cccc(NC(=O)Cn2nc3n(c2=O)CCCCC3)c1 +O=c1c(CSc2ccccn2)cc2cccc3c2n1CCC3 +Cc1nnc(N2CCN(C(=O)c3cccc(F)c3)CC2)c(C#N)c1C +CC(NC(=O)COC1CCCCC1)C(=O)NCc1ccccc1 +CCCCn1ncc(C(=O)Nc2ccc(C(C)=O)c(C)c2)c1C +COCCN(C)C(=O)C(C)NC(=O)c1cccs1 +O=C(NC1(C(=O)N2CCCC2)CCCC1)c1cncc2cnccc12 +CCOc1cccc(NC(=O)c2ccc(N3CCOCC3)cc2)c1 +Cc1ccc(C(=O)N2CCN(c3ncccc3C#N)CC2)c(O)c1 +CCCC(NC(=O)c1cccc(N2CCCC2=O)c1)c1cccs1 +O=C(CCSc1ccccc1F)NCCc1cscn1 +CCOc1cccc(C(C#N)N(C)C(=O)c2ccc(F)cc2)c1 +CC(C#N)OC(=O)c1ccc(COc2ccc(F)cc2)o1 +O=C(Nc1nc2c(s1)CN(C(=O)Cc1cccs1)CC2)C1CC1 +O=C(NCc1ccccc1CN1CCCC1=O)c1ccco1 +COCC1COCCC12CCN(S(=O)(=O)c1cccnc1)CC2 +COc1cc(C)c(C)cc1S(=O)(=O)NCc1sc(C)nc1C +c1coc(-c2nnc3sc(Cn4cccn4)nn23)c1 +Cc1ccc(-n2nnc(-c3cccnc3)c2N)cc1C +Cc1ccc(N)c2nnc(-c3ccc(Br)cc3)n12 +C=CCOCC1CCCC12CN(Cc1cccnc1)CCO2 +Cc1noc(C)c1CCC(=O)N(C)CCOc1ccccc1 +CC(C)(C)CC(=O)NCC(=O)OCc1nccs1 +Cc1cc(C)cc(C(=O)NCC(=O)NC2CCC(O)CC2)c1 +CC(=O)N1CCCc2cc(NC(=O)COCc3nc(C)no3)ccc21 +CCOc1ccc(C(=O)N(Cc2cccnc2)CC2CCCO2)cn1 +COCCNC(=O)C(C)Sc1nnc2c(n1)[nH]c1ccccc12 +N#Cc1ccccc1OCC(=O)Nc1ccc(NC(=O)C2CC2)cc1 +CC(=O)c1cc(-c2cccc3cccnc23)ccc1O +CCn1cc(CC(=O)NCc2ccccc2)c2cccnc21 +CCn1cc(C(=O)Nc2sc(C)c(C)c2C(=O)OC)c(C)n1 +NC(=O)C1CCCCC1NS(=O)(=O)c1ccc(F)c(F)c1F +O=C(NCC(=O)c1ccco1)c1ncn(-c2ccccc2)n1 +O=C(NCCc1ccsc1)N1CCN(Cc2ccccn2)CC1 +CN(C)C(CNc1ncnc2c1cnn2CCC#N)c1cccs1 +CCOc1ccc(NS(=O)(=O)c2cccnc2)cc1 +CCCCn1c(=O)n(CC)c(=O)c2c1nc(NCC)n2C +Cc1ccc(CNC(=O)NCC(=O)Nc2cccc(F)c2)cc1 +Nc1ccc(O)c(-c2n[nH]c(-c3ccc(C(F)(F)F)cc3)n2)c1 +CC(C)Nc1cccc(CNC(=O)CCn2ccccc2=O)c1 +O=C(c1ccc(-c2ccco2)[nH]c1=O)N(Cc1ccccn1)C1CC1 +CN(C)c1ccnc(C(=O)Nc2ccccc2Cn2cncn2)c1 +N#Cc1cccc(CNC(=O)c2ccc3c(c2)OCC(=O)N3)c1 +COCCN(Cc1ccc2c(c1)OCCO2)Cc1sccc1C +COc1cc(NC(=O)C(C)C)ccc1N1CCCCC1=O +Cc1cccc(C2(C(=O)NCCNc3cnccn3)CC2)c1 +CC(=O)Nc1cccc(NC(=O)c2ccc(NC(=O)C3CC3)s2)c1 +O=S(=O)(NCCc1cn2ccccc2n1)c1cccc2nonc12 +CCN(CCNC(=O)c1ccccc1O)C(=O)OC(C)(C)C +CSc1ccc(Nc2ccc(N)cc2C(N)=O)cc1 +CN(Cc1ccc2ccccc2n1)C(=O)c1ccc(N(C)C)nc1 +O=C(Nc1nc2cc3c(cc2s1)OCCO3)C1CCC1 +O=C(NCc1ccnc(OC2CCC2)c1)NCC1(C2CC2)CC1 +CCCc1c(C(=O)N(C)CC(=O)NC2CC2)[nH]c(C)c1C(C)=O +Cc1nn(C)c(C)c1C(=O)Nc1ccc(Cl)cc1F +COc1cccc(C(=O)NCC(=O)Nc2ccc(Cl)cc2C)c1 +Cc1noc(NC(=O)Nc2cccc(C(F)(F)F)c2)c1C +COc1cccc(C(=O)Nc2cccc(S(C)(=O)=O)c2)c1 +Cc1ccccc1CN(C)C(=O)CNS(C)(=O)=O +O=C1CC(CNC(=O)Nc2ccc3c(c2)COC3)c2ccccc2N1 +COc1cc(Cl)c(C)cc1N1C(=O)CCS1(=O)=O +COc1ccccc1-c1cc(=O)c2c(O)cccc2o1 +COCCNC(=O)Nc1ccc(N(C)C(C)C)c(F)c1 +CNC(=O)c1ccc(NC(=O)N2CC(C)CC(C)C2)cc1Cl +CC1Oc2ccccc2N(CC(=O)Nc2c[nH]ccc2=O)C1=O +N#CCCN(CCC(F)(F)F)C(=O)c1ccccn1 +CNC(=O)COC(=O)c1cc(N2CCCC2=O)ccc1Cl +O=S1(=O)N=C(N2CCCC2CO)c2ccccc21 +CC(C)Cc1ccc(C(=O)NC2CCCNC2=O)cc1 +COc1cccc2cc(C(=O)N(C)C3(C#N)CCC3)oc12 +COc1ccccc1OCCC(=O)N=c1sccn1C +COc1ccccc1-c1nnc(NC(=O)c2ccc(N(C)C)cc2)o1 +CN(C)C(=O)C12CCC(c3nc(C#N)c(C#N)nc31)C2(C)C +COc1ccc(-c2cc(CO)nn2CC(C)C)cc1C +COc1ccccc1NCC(=O)NCC(O)c1ccccc1C +Nc1ncc(C(=O)N2CCC3(CCCO3)CC2)c(-c2ccccc2)n1 +O=C(CCSc1nnnn1C1CCCC1)Nc1cccc(F)c1 +COc1ccc2oc(C(=O)OCCOC(C)C)c(C)c2c1 +CC1(NS(=O)(=O)c2ccc(C(N)=O)cc2)Cc2ccccc2C1 +Cc1ccc(C(=O)NCc2nc3ccccc3[nH]2)cc1 +N#Cc1ncn(Cc2c(Cl)ccc3cccnc23)c1C#N +COC(=O)C(C)CS(=O)(=O)c1ccc(C(C)C)cc1 +O=C(CN1CCOCC1)NCCOc1ccc(F)cc1 +O=C(NCC1CN2CCCCC2CO1)Nc1ccccc1Cl +COC(=O)CNC(=O)Cn1ccc(=O)c2ccccc21 +CC(NC(=O)NCC(=O)NC(C)(C)C)c1ccc(C(F)(F)F)cc1 +COC(=O)C1=C(C)Nc2ncnn2C1c1cnn(C)c1C +CCOC(=O)CNC(=O)NC(C)c1ccc(F)c(F)c1 +N#Cc1ccc(CNC(=O)N(Cc2ccccc2)C2CC2)cc1 +Cc1cccc(C(=O)Nc2ccc(-c3cnc(C)o3)cc2)n1 +CCC(C)NC(=O)c1ccc(NC(=O)N2CCCC(C)C2)cc1 +Cc1n[nH]c(NCc2ccc(Cl)cc2)nc1=O +Cc1noc2nc(-c3ccccc3)cc(C(=O)NCc3ccccn3)c12 +COc1ccc(NC(=O)NC(C)C(C)C)cc1N1CCCC1=O +CCc1nccn1Cc1ccc(OC)c(Br)c1 +CN(CC12CC3CC(CC(C3)C1)C2)C(=O)CNC(=O)c1cccs1 +Cc1occc1C(=O)N1CCN(C(=O)c2cc(C(C)C)nn2C)CC1 +CC(C)CNC(=O)N1CCN(c2ccccc2F)CC1 +COC(=O)c1ccc(OCc2ccccc2)c(OC)c1 +CC(C)CN(Cc1cccc2cn[nH]c12)CC(F)(F)F +CCc1ocnc1C(=O)NC(CC)c1nc(C(F)(F)F)cs1 +C=CCn1c(N)cc(=O)nc1SCC(=O)Nc1cc(C)cc(C)c1 +C(=CC1NCCc2ccc3c(c21)CCO3)c1ccco1 +COC(=O)NCCn1nc(C(F)(F)F)c2c1CCOC2 +COc1cc(OC)c(NC(=O)COCC2CC2)cc1F +N#CCOc1cccc(CC(=O)Nc2cccc(NC(=O)C3CC3)c2)c1 +CN(C)C(=O)c1ccc(Oc2c(C#N)c(=O)n(C)c(=O)n2C)cc1 +Cc1noc(COc2cccc(OCC(F)(F)F)c2)n1 +CC(=O)NCc1ccc(S(=O)(=O)NCC2CCOC2)s1 +CNC(=O)Cc1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1 +Nc1cc(F)ccc1C1NCCc2c(F)ccc(F)c21 +CCCn1cc(NCc2ccc(C3CC3C)o2)cn1 +CCCS(=O)(=O)N1CCN(c2ccc(Cl)cn2)CC1 +Cc1ccc(Cn2cnc3ccccc3c2=O)cc1 +COC(=O)c1ccc(C)c(C(O)c2ccncc2)c1 +COC(=O)c1ccc(C(=O)NCC(O)C2CCCCC2)cc1 +CCC(C)n1ncc(C(=O)NCC2(OC)CCOCC2)c1C1CC1 +c1ccc(-n2ncc3c(NCc4nncn4C4CC4)ncnc32)cc1 +COc1ccc(NC(=O)Cn2nnc(-c3ccc(N)cc3)n2)cc1 +Cc1nc(C2CCCN2S(=O)(=O)c2cn(C)cn2)no1 +CN1C(=O)CCC(C(=O)N2CCOCC2)C1c1ccccc1 +O=C(NCc1cccc(C(=O)NCc2ccco2)c1)Nc1ccccc1 +CCC(NCC(=O)N1CCCc2ccccc21)c1ccccc1 +Cc1cccc(-c2nc(CN(C)Cc3nonc3C)c(C)o2)c1 +CCC(C)(NC(=O)NCC1CN2CCCCC2CO1)c1ccccc1 +C#CCN1CCN(C(=O)NCCC2=CCCC2)CC1 +O=C(Cc1ccco1)N1CCCC2(CC(OCC3CC3)CO2)C1 +O=C(C1CC(=O)N(c2ccc(F)cc2)C1)N1CCCCCC1 +O=C(Nc1ccc2c(c1)CCC2)c1ncoc1-c1cccs1 +O=C(CCc1cn2cccnc2n1)NC1CCCC1 +O=C(NCCCN1CCc2ccccc21)c1cccs1 +CC(=O)c1ccc(NC(=O)CCSc2ccccc2)cc1 +COC(=O)c1nnn(CCOc2ccc(Cl)cc2)c1N +COC(=O)C1(N(C)C(=O)c2cc(C(C)C)[nH]n2)CCCCC1 +CC(O)(CNC(=O)c1ccc2c(c1)NC(=O)CS2)c1ccsc1 +O=C(c1cccc2c1-c1ccccc1C2)N1CCOCC1 +Cc1ccccc1OCC(=O)N(CC(F)(F)F)C1CCOCC1 +Cc1cccc(C(=O)NCCNc2ccc(N)cn2)c1 +COCC1CCCN1C(=O)Cn1nnnc1CN1CCOCC1 +CCCc1nnc(NC(=O)c2cc(C)nc3c2cnn3C(C)C)s1 +CCNC(=O)N1CCC(c2nc3cc(OC)ccc3[nH]2)C1 +CNC(=O)NCC(=O)NC(C)c1c(F)cccc1Cl +CCOC(=O)c1cn2cc(C(F)(F)F)ccc2n1 +COc1ccc(NC(=O)c2cc(C)n3nccc3n2)cc1F +COc1ccc(NC(=O)NCCNC(=O)c2ccco2)cc1Cl +CC1=CCN(C(=O)Nc2c(C)nn(C(C)C)c2C)CC1 +COCCOc1cc(C)ccc1NCc1csnn1 +Cc1noc2nc(-c3ccco3)cc(C(=O)N(C)C(C)C)c12 +Cc1ccc(C)c(CC(=O)Nc2nnc(-c3csc(C)n3)o2)c1 +CC(Cc1ccc(O)cc1)N(C)Cc1ccnn1C +CC(C)(C)Oc1cc(CNC(=O)N2CCCC(CO)C2)ccn1 +Cc1nc(=O)c2c([nH]1)CN(Cc1ccccc1F)CC2 +Cn1cc(C(OC(=O)c2ccc3nnn(C)c3c2)C(F)(F)F)cn1 +CN(C)C(=O)c1ccc(CN2CCC(Oc3cccc(Cl)c3)C2)[nH]1 +CCCNC(=O)Nc1ccc(-c2nnc(N(C)C)o2)cc1 +CCCCS(=O)(=O)NCC(=O)NC1CC2CCC1(C)C2(C)C +CC(C)Oc1ccc(CNC(=O)c2ccco2)cc1F +CCOCc1ccccc1CNC(=O)c1cnn(-c2ccccc2)c1 +N#CC(C(=O)c1scnc1C1CC1)c1ccc(C(F)(F)F)cn1 +Cc1ccc(O)c(C(=O)c2cnn(C(=O)c3cccnc3)c2)c1 +CC1CC1C(=O)NCc1ccc(OCC(F)(F)F)nc1 +CCc1cccc2c(CC(=O)NCc3csc(=O)[nH]3)c[nH]c12 +Oc1cc(-n2cnnn2)ccc1-c1nc(C2CC2)nn1-c1ccccc1 +Cc1cc(C)n(CC2CCCCN2C(=O)C(C)N2CCOCC2)n1 +COC(=O)CCNC(=O)c1cnc2scc(C)n2c1=O +COC(=O)c1ccc(CN2CCOCC2CC(C)C)cc1 +COCCNC(=O)Cn1nc(-c2cccc3ccccc23)ccc1=O +CCCNC(=O)c1cccc(NC(=O)c2nnc(C3CC3)s2)c1 +COc1ccccc1C(=O)Nc1cc(C)nn1CCC#N +CN(C)c1cc(C(=O)NC2CCCCC2)nc2ccnn12 +CCS(=O)(=O)n1nc(-c2ccc(OC)cc2OC)cc1N +COc1ccc(-c2noc(C3CC3c3cccnc3)n2)cn1 +C=CCc1cc(C(=O)Nc2ncccc2C)cc(OC)c1OC +CCn1c(=O)c(=O)n(CC(=O)NCCC(C)C)c2ccccc21 +CCS(=O)(=O)NCC(O)c1cc(F)ccc1OC +COC(=O)CN1CCN(c2ncnc3cc(F)c(F)cc23)CC1 +CC(C)Oc1ccc(C#N)cc1NCc1cc[nH]n1 +COc1ccc(Cl)cc1NC(=O)NCC(O)c1cccs1 +CCC1CN(C(C)=O)CCC1NC(C)C(=O)NCC(F)(F)F +O=C(Cn1cc(Cl)cn1)c1cc(F)ccc1F +CC(CC#N)NS(=O)(=O)c1ccccc1Cl +CCNC(=O)c1ccc(CNC(=O)CCc2c(C)nn(C)c2C)cc1 +CC(C)CNC(=O)c1cccc(-n2ccnc2)c1F +COCCCC(=O)N1CCC(Cc2ccc(OC)cc2)CC1 +CCOC(C)c1nc(COc2ccccc2C(=O)NC)cs1 +O=C(NCCc1cccs1)c1ccccc1-n1cnnn1 +C=C(C)CN(CC)C(=O)c1cccc(-n2cccc2)c1 +O=C(Nc1ccccc1CN1CCNC1=O)c1ccccc1Cl +CCN(CC(=O)NC(C)(C)C)C(=O)c1cnn(-c2ccccc2F)c1 +CN1C(=O)CC(c2ncnn2C2Cc3ccccc3C2)c2ccccc21 +Cc1cccc(C)c1CN1CCN(C(=O)c2ccc(O)cc2)CC1 +CCC(=O)Nc1cc(S(C)(=O)=O)ccc1Cl +Clc1ccc(CN2CCN(Cc3nc4ccccc4[nH]3)CC2)cc1 +O=C(NCCCOc1ccccc1)c1csnn1 +COc1cc(C)c(CN2CCNC(=O)C2Cc2ccccc2)cc1C +CS(=O)(=O)N1CCc2ccc(NC(=O)Nc3cccc(F)c3)cc21 +CCC(=O)Nc1cc(NC(=O)CNc2c(C)cccc2C)ccc1C +Cc1nc(NC(=O)c2ccc3c(c2)OCO3)sc1C +Cn1c(SCCCC#N)nc2ccsc2c1=O +Cc1ccc(C)c(OCCCCC(=O)NC2CCCCNC2=O)c1 +Cc1ccc(CN2C(=O)CCC2C(=O)Nc2ccc(C#N)cn2)cc1 +COc1ccc(F)cc1NC(=O)N1CC2OCCN(C)C2C1 +CC(C)CCN(CCC#N)C(=O)c1scnc1C1CC1 +Cn1ccc2c(Br)ccc(O)c2c1=O +Cc1cc(C(=O)Nc2ccccc2Br)on1 +C=CCOC1C(O)C(CO)OC1n1cnc2c(=O)[nH]c(N)nc21 +CC(C)COc1ccccc1-c1ccc(C(N)=O)c(N)n1 +Cc1cc(C)n2nc(C(=O)NCc3cccc4ccccc34)nc2n1 +COCCNC(=O)CCCc1nc2ccccc2s1 +Nc1cc(F)cc2c(=O)cc(C(=O)Nc3nccs3)oc12 +COCCNC(=O)c1csc(-c2ccc(OC)cc2Cl)n1 +O=C(NCCOc1ccc(Cl)cc1)c1cccc2ccnn12 +CSc1ccc(NC(=O)c2cn(C)c3ncccc23)cc1 +COc1cc(OC)c(CNC(=O)NCC(F)(F)F)c(OC)c1 +Cc1ccc(-c2cnnc(NCc3n[nH]c4c3CCCCC4)n2)o1 +CCOC(=O)CN(CC)C(=O)c1cc(N)ccc1Cl +O=C(CCn1ncc2ccccc21)Nc1ccc2c(c1)OCO2 +CC(C)N(CCCO)C(=O)c1ccc(F)c(F)c1 +CCc1nc(CC(=O)N2CCCC2c2cnn(C)c2)cs1 +CC(C)NC(=O)CC1C2CN(C(=O)Cc3ccccn3)CC12 +O=C(NCC1CC1)C1CN(Cc2ccncc2)CC12CCOCC2 +Cc1cc(C(F)(F)F)nc(CCNc2cc(C)nc3ccnn23)n1 +CC1CCN(C(=O)C2CCN(C(=O)c3ccccc3)CC2)CC1 +Cc1cc(C)n(C(C)CC(=O)NC2CCC(C)CC2)n1 +CNC(=O)C1CC2CN(S(=O)(=O)c3ccccc3)CC1O2 +NC(=O)c1ccc(NCCc2cn3ccsc3n2)nc1 +Cc1ccsc1CNc1cn[nH]c(=O)c1Cl +COc1ccccc1CNC(=O)CCn1ncc2cccc(C)c21 +COc1ccc(C(=O)Nc2cccc(C(C)=O)c2)c(OC)c1 +Cc1noc(-c2ccc(NCc3ccccc3-n3cncn3)nc2)n1 +CCOCc1cccc(NC(=O)C(OC)c2ccccc2)c1 +CCCc1cc(N2CCOC(Cn3cncn3)C2)n2ncnc2n1 +COCCS(=O)(=O)N1CCCCC1CCc1ccccc1 +CC(=O)N1CCN(C(=O)C2CC2c2ccccc2C)CC1 +CNC(=O)c1cccc(CNc2cccc(C(C)=O)c2)c1 +O=C(c1ccc(-c2ccccc2Cl)o1)N1CCC(O)CC1 +O=C(Nc1nc[nH]n1)c1cccnc1Sc1ccccc1 +Cc1ccc(C(=O)N(C)Cc2ccccc2F)s1 +CC(NC(=O)NCCC1(C)OCCO1)c1ccc(F)cc1F +O=C(CCNC(=O)C1CCOc2ccccc2C1)NC1CCCCC1 +CCOC(=O)CC1CCN(C(=O)Cn2c(C)c(C)sc2=O)CC1 +CCC(CO)Nc1ncnc2c1cnn2-c1ccccc1C +CC(C)COc1cc(C(=O)NCc2cccnc2)ccc1N +CCOC(=O)CNC(=O)CN(C)c1ccccc1 +CC1CCCCN1C(=O)c1cc(-c2cnc(N(C)C)nc2)cn1C +CSc1nnc(SC(C)C(=O)NC(C)c2ccccc2)s1 +CN(CC(N)=O)S(=O)(=O)c1cccc(Cl)c1 +CCc1sc2nc[nH]c(=O)c2c1-c1cccc(OC)c1 +CCCNC(=O)CCNC(=O)N(C)Cc1nc2ccccc2s1 +CC(=O)Nc1cc(NCC(=O)NC2CC2)ccc1F +CCOCCCNC(=O)Nc1cnn(-c2ccccc2F)c1 +CN(C(=O)CSc1cn[nH]n1)C1CCCCC1 +Cc1nn2ccccc2c1C(=O)N1CCCC1C(=O)NCC(C)C +CCc1nc(CCNC(=O)Cc2c(F)cccc2F)sc1C +Cc1ccc(OCCN2CCOCC2)c(C(C)O)c1 +Cc1cc(C2CCCCCN2C(=O)c2c(Cl)cnn2C)on1 +CC1=C(C(=O)N(C)C)C(c2ccc(Cl)cc2)NC(=O)N1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)c1cccnc1 +Cc1cc(C)c2cc(C(=O)Nc3cccnc3-n3ccnc3C)[nH]c2c1 +O=C(CCc1cc2ccccc2[nH]c1=O)N1CCCCC1 +O=C(NCc1cccnc1Oc1ccccc1)C1CCOC1 +O=C1CCC(C2NCCc3c(Cl)ccc(Cl)c32)N1 +Cc1cc(C)n2ncc(C(=O)NCc3c[nH]nc3C)c2n1 +CCc1nc(CCNC(=O)Nc2ccc(NC(=O)OC)cc2)cs1 +CCN(Cc1cnn(C(C)C)c1)Cc1cc(=O)c2cccc(F)c2[nH]1 +COC1CCN(C(=O)Cn2c(=O)c3c(ncn3C)n(C)c2=O)CC1 +CNc1snc(C)c1C(=O)OCc1cc(=O)n2ccsc2n1 +CC(CNC(=O)N1CCOC(C)C1)CN(C)C(=O)OC(C)(C)C +CCCc1cc(C(=O)NCc2ccc(C(=O)N3CCCC3)cc2)[nH]n1 +O=C(NCc1ccccn1)c1ccc(CS(=O)c2ccccc2)o1 +COCCC1(C(=O)N2CCC(OCc3ccccc3C)CC2)CC1 +O=C(CC1CCCC1)NCCNC(=O)N1CCOCC1C1CC1 +O=C1CCCC2(CCN(C(=O)OCc3ccccc3)C2)N1 +CN1CC(NC(=O)Cc2cccc(Cl)c2)CCC1=O +CCOC(=O)N1c2ccccc2C(c2ccccc2)=NC1C#N +Cc1ccc(CC(=O)N2CCC(Oc3ccccc3)CC2)cc1 +CN(C(=O)c1ccc(OCC(F)F)nc1)c1cccc2ncccc12 +CCCc1cc(=O)oc2cc(C)cc(OC(C)=O)c12 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+N#Cc1cccc(CNS(=O)(=O)c2cc(Cl)cnc2N)c1 +CCn1cc(C#N)c(=O)n(CC(=O)c2ccc(NC(C)=O)cc2)c1=O +COCCNC(=O)c1cc(-c2ccccc2Cl)[nH]n1 +CCCCN(C)C(=O)Cn1nc(C)c2ccccc2c1=O +Cc1cccc(S(=O)(=O)NCC(O)c2ccc3c(c2)CCO3)c1 +COCC(C)NC(=O)CSc1nnnn1-c1ccccc1 +COc1ccc(C(=O)N2CCC(n3cnc4ccccc43)CC2)cc1 +CC(C)N(CCCO)S(=O)(=O)N1CCCCC1C +Cc1ccc(C(=O)N(CCC#N)C2CCCC2)cc1C +COC(=O)c1ccccc1C(=O)Nc1nc2ccc(OC)cc2s1 +COc1cccc(C(=O)N2CCc3cc(N)ccc32)c1OC +COc1cc(C)c(S(=O)(=O)Oc2ccc3c(c2)CCC3)cc1OC +COc1ccc(Cl)cc1CCNC(=O)CCC#N +CCc1nc2ccc(C(=O)NCc3ccc(C)o3)cc2nc1CC +COc1cc(C)ccc1OC(=O)C(C)NC(=O)c1ccco1 +O=S(=O)(NCc1ccccn1)c1ccc(F)c(F)c1F +CCn1nnnc1-c1cccc(NCc2csc(C3CC3)n2)c1 +CC(C)(C)NC(=O)C(C#N)Cc1ccc(Cl)cc1 +CS(=O)(=O)N1CCc2cc(C(=O)NCc3ccco3)ccc21 +COC(=O)C12CC=CCC1(C(=O)OC)CC=CC2 +CC(NC(=O)CSc1ccncc1)C(O)c1ccc(F)cc1 +COc1cc(OC)cc(C(=O)N2CCNC(=O)C2C)c1 +CCN(C(=O)CC(NC(C)=O)c1ccc(OC)cc1)C1CCCCC1 +Cc1ccnc(NC(=O)CCSc2ccc(F)c(F)c2)c1 +Cc1cc(C(O)CNCc2ccccc2F)ccc1F +C=CCNC(=O)COc1ccc(S(=O)(=O)N2CCOCC2)cc1 +CCN(CCc1ccccc1)C(=O)Nc1ccncc1 +Cn1cc(C(=O)NCc2ccnc(OC3CCCCC3)c2)ccc1=O +CC(NS(C)(=O)=O)C(=O)NC1CCN(c2c(F)cccc2F)C1 +CN(CC(=O)N1CCCC(C(F)(F)F)C1)c1ccc(C#N)cn1 +CCC1CCCCC1OC(=O)CN(C)S(=O)(=O)c1cccnc1 +O=C(OCc1cncs1)c1nccc2ccccc12 +CC(C)C(=O)Nc1ccc(CNC(=O)NCCc2ccccn2)cc1 +CC(=O)N1CCC(NS(=O)(=O)c2cn(C)c(=O)n(C)c2=O)CC1 +CCCCc1c(C#N)nnn1-c1cccc(C(=O)OC)c1 +N#CC(C(=O)NC1CCCCC1)c1nc2ccccc2s1 +O=C(c1ccc(-c2ccc(F)cc2)o1)N1CCOCC1C1CC1 +CCC(=O)Nc1cccc(NCC(=O)Nc2c(C)cccc2C)c1C +CCc1nc(CC(=O)Oc2ccc(C)c(C)c2)cs1 +CCCn1cc2c3c(cccc31)CN(C(=O)C1CCCO1)CC2 +CCCCN(CC)C(=O)c1onc(-c2ccccc2C)c1N +COC(=O)c1cc(-c2ccc3c(c2)NC(=O)CO3)[nH]c1N +N#CCCN(CCC(F)(F)F)C(=O)c1cccc(-n2cncn2)c1 +CC(=O)Nc1cccc(OCC#CCNC(=O)c2cc(C)on2)c1 +CCOc1ccc(C(=O)C(C)NCc2ccccn2)cc1N +COc1ccc(NC(=O)c2nc3ccc(Cl)cn3c2C)cc1OC +O=C(CCc1ccc2c(c1)OCO2)Nc1cccc(-n2cnnc2)c1 +Cc1cc(C(=O)OC(C)C(=O)NC(C)(C)C)c(C)n1Cc1ccco1 +Cc1cc(C)c(NC(=O)c2cnc(C)cn2)c(Cl)c1 +C=C(C)COc1ccc(C(=O)NCc2ccco2)cc1 +Fc1ccc(-c2csc(Cc3nnc4n3CCCCC4)n2)cc1 +c1ccc(CNc2ccc(N3CCCCC3)nn2)cc1 +Cc1cc(NCCCN2CCOCC2)cc(=O)n1CC1CCCO1 +Cn1c(SCCOc2ccccc2F)nnc1-c1cccnc1 +CN1CCN(C(=O)CC2Sc3ncccc3N(C)C2=O)CC1 +COC(=O)C1CCCN(C(=O)c2cccnc2N)C1 +O=C1Cc2cc(-c3csc(-c4cccnc4)n3)ccc2N1 +CS(=O)(=O)N1CCC2(CCCN(C(=O)Cc3cccnc3)C2)C1 +Cc1noc(-c2ccc3c(c2)nc(C)n3C(C)C)c1N +COc1ccc(C(C)=O)cc1CC(=O)Nc1cccc(C)c1 +CCCN(Cc1nnnn1C1CC1)CC1COc2ccccc2O1 +Fc1ccc(-c2nc3cc4c(cc3[nH]2)OCCO4)c(F)c1 +Cc1nc(-c2cccc(C(=O)NCCC(=O)N3CCCC3)c2)n[nH]1 +CCCCn1c(N)c(N(C)Cc2ccc(F)cc2F)c(=O)[nH]c1=O +Nc1ccc(NCCc2ccsc2)c2nonc12 +CCOc1cc(N)cnc1Nc1ccc(C(C)=O)cc1 +CCc1nc(-c2noc3ccc(C(=O)Nc4ccc(C)cn4)cc23)co1 +COc1ccc(CNC(=O)c2cc3cnsc3s2)c(OC)c1 +c1ccc(NCCCc2nnc3cnccn23)cc1 +CCOC(=O)CN(C)C(=O)CCc1cc(Cl)cs1 +CC(NC(=O)c1ccc(OCC(N)=O)cc1)c1ccccc1F +O=C(CCOc1ccc(Cl)cc1)N1CCC(O)CC1 +COC(=O)c1sc(SC)c(C#N)c1-c1ccco1 +Cc1ccc2c(c1)CC(c1ccc3c(c1)OCCO3)N2 +COC(=O)C(O)c1ccc2c(c1)nc(C(C)C)n2C +COc1cc(OC)c(NC(=O)C2CCCO2)cc1Cl +O=C(NCc1ccccc1)c1sccc1C1CC1 +O=c1[nH]cnc2nc(N3CCCCCC3)sc12 +CCn1nc(C(C)C)cc1C(=O)N1CCN(CCn2cccc2)CC1 +CC(NS(=O)(=O)c1ccc(C#N)cc1)c1cccs1 +COc1ccnc(NC(=O)c2conc2-c2ccc(Cl)cc2)c1 +CSc1ccccc1NC(=O)CN(C)C(=O)c1ccco1 +Nc1cccc(-c2csc(NC(=O)c3ccc(F)cc3)n2)c1 +CCOC(C)c1noc(COc2ccc3c(CC)cc(=O)oc3c2)n1 +CCC(C)(C)C(=O)N(C)CCN(C)C(=O)OC(C)(C)C +COc1c(Cl)ccc(Cl)c1C(N)c1nc(C)c(C)s1 +Nc1c(-c2cccnc2)nc2scc(-c3cccs3)n12 +COCCOc1cccc(CNC(=O)N2CCOCC2C)c1 +Cc1ccc(N(C)CC(=O)N(C)CC(=O)NC2CC2)c(C)c1 +Cc1csc(C2CN(c3ccc4nnnn4n3)CCO2)n1 +Cc1ccncc1NC(=O)NCc1coc(-c2cccs2)n1 +CC(C)OC(=O)CSc1nc2c(cc1C#N)C(=O)CCC2 +COC(=O)Cn1ccc2c(cnc3ncnn32)c1=O +CCOC1COC2(CCCN(C(=O)c3ccc(F)cc3C)C2)C1 +CN(Cc1cccnc1)c1cc(C(F)(F)F)nc2ncnn12 +COC(=O)Nc1ccc(N(C(=O)OC)c2ccccc2)cc1 +O=C1c2ccccc2COC12OCc1ccccc12 +Cc1ccc2c(=O)cc(C(=O)NCc3ccc4c(c3)OCO4)oc2c1 +O=c1cc(C(F)(F)F)c2c(F)cc(F)cc2o1 +O=C(NCc1ccc(=O)[nH]c1)c1cnc(-c2ccccc2)nc1 +O=S(=O)(CCCO)NCCc1ccc(Cl)c(Cl)c1 +CCS(=O)(=O)NCc1ccccc1-n1ccnc1C +CCn1cc(S(=O)(=O)Nc2cn[nH]c2)c(N)n1 +Cn1ccc(C(=O)N2C3CCC2CC(O)(c2ccnn2C)C3)n1 +Cn1cc(NC(=O)c2ccc(OCC3CC3)cc2)cn1 +Cc1ncc(C(=O)N2CCCC2C(=O)N2CCOCC2)c(=O)[nH]1 +CCCC(=O)NCC(c1ccccc1Cl)N1CCOCC1 +CCCS(=O)(=O)Nc1ccc(C#CCO)cc1F +O=C1CCN(Cc2nc3c(s2)CC(c2ccccc2)CC3)CCN1 +CCOC(C)C(=O)Nc1ccc(C(=O)Nc2nccs2)cc1 +CC1C(=O)N(c2ccc(F)cc2F)CCN1C(=O)C(C)(C)C +CN1CC(=O)N(C)c2ncn(Cc3ccccc3)c2C1=O +Cn1cc(-c2csc(CN3CCOCC3)n2)cn1 +CCCc1ccc(C(=O)N2CCCC(S(=O)(=O)NC)C2)cc1 +CCOC(=O)N1CCC(NC(=O)c2ccc(-n3cnnn3)cc2)CC1 +CCC1Nc2cc(F)ccc2N(C(CC)C(N)=O)C1=O +COc1ccc(S(=O)(=O)n2ccc(C)n2)cc1 +CCc1ccc(C(=O)Nc2n[nH]c3ccccc23)o1 +CC(C)C1Oc2c(Br)cc(F)cc2N(C)C1=O +COCC1CCN(C(=O)c2cccnc2OCC(F)F)CC1 +O=C(NC1CC1)c1cn2c(n1)CN(C(=O)Cc1cccc(F)c1)CC2 +Cc1ccc(Cl)cc1NC(=O)NCCCOCC1CCCO1 +CC1CN(c2nccc(C3CCCC3)n2)CC1(C)O +O=C(Cn1nnc(-c2ccc(F)cc2)n1)c1cccs1 +O=C(NCCC1=CCCCC1)c1nc2ccccc2c(=O)[nH]1 +O=C(c1cccs1)N1CCC(O)C1Cc1ccccc1 +c1ccc(CNc2ccc(-n3cncn3)cc2)cc1 +COC(=O)c1cccc(NC(=O)c2ccco2)c1C +CCCc1cc(C(=O)OCC(=O)Nc2sccc2C#N)sc1C +CCC(C)(NC(=O)CCn1ncc(=O)c2ccccc21)c1ccccc1 +O=C(COc1ccc(Cl)cc1)Nc1ccnc2ccc(F)cc12 +CN(Cc1ccccc1)C(=O)COc1cccc2c1OC(C)(C)C2 +CN(Cc1ccncc1)C(=O)NC1CCN(C(=O)C2CCCC2)C1 +CSc1ccc(NC(=O)Oc2cccc3ccc(C)nc23)cc1 +O=C(Cc1ccc(O)c(Cl)c1)N1CC2CC(O)C(O)CC2C1 +CC(C)NS(=O)(=O)c1ccc(C(=O)Nc2cccnc2)cc1 +Cn1cc(C(=O)Nc2ccccc2)c(=O)c2c(N)cccc21 +C=CCCC(=O)Nc1ccc(Oc2cccnc2)nc1 +COc1ccc(N)cc1OCc1cc(Br)ccc1F +Cc1ccc(CCNC(=O)C2CC(=O)N(C3CCCC3)C2)s1 +Cc1cc(NC(=O)c2cccc(C(F)(F)F)c2)sn1 +COc1ccc2c(CC(=O)NC3C4CCOC4C3(C)C)coc2c1 +Cc1cc(C)n(CC(=O)Nc2ccc(C(C)C)cc2)c(=O)c1C#N +CCN(c1ccccc1)S(=O)(=O)c1ccccc1F +COC1CCC(N(C)C(=O)c2ccc(-c3nc(C)cs3)cc2)CC1 +Cc1cccc(N2CCN(C(=O)c3cc(C)n4nccc4n3)CC2)c1 +CC(C)N(C)C(=O)CCCn1ccc2cc(Cl)ccc21 +CN(C)C(=O)c1ccccc1NCCCc1ccccc1 +Cc1cnc(NC(=O)c2sc(-n3cccc3)nc2C)s1 +c1ccc(-n2cnnc2CNc2nc3ccccc3o2)cc1 +CCOC1CC1C(=O)N1CCCCC1c1nc(C)cs1 +CN(CC1CCC1)C(=O)CCc1nc2ccccc2c(=O)n1C1CC1 +Cc1ccc(S(=O)(=O)N(C)C(C)C)c2c1NCCC2 +CCOc1cc(N2CCCC(C(=O)NCC(F)(F)F)C2)ncn1 +CCn1c(=O)n(CC(=O)NCCCC(N)=O)c2ccccc21 +O=C(COc1ccc2nc3n(c(=O)c2c1)CCC3)Nc1ccccn1 +Clc1ccc(-c2nc(-c3ccncc3)n[nH]2)cc1 +COC(=O)c1cc(C(=O)OC)n(Cc2ccc(F)cc2)c1C +COc1ccccc1NC(=O)c1sc(-c2ccncc2)nc1C +CC(C)CCNC(=O)c1nc(N2CCCCC2)c2cnn(C)c2n1 +CCN(Cc1cccs1)c1ncnc2c1cnn2CCC#N +CCCC1CN(C(=O)C(C)OC2CCCC(C)C2)CCO1 +CC(=O)Nc1ccc(NC(=O)N(C)C(C)c2ccccn2)cc1 +CCN(CC(=O)Nc1cc(Cl)ccc1C)C(=O)Cc1cc(C)on1 +CC(C)Oc1ccc(NC(=O)N2CCOCC2C2CC2)cc1 +CCNC(=O)Nc1ccc(C(=O)N2CCCC2)cc1 +Cc1nnc(SCC(O)CN2CC(C)OC(C)C2)s1 +Cc1nnc(CN(C)C(=O)c2ccc(Cl)c(Cl)c2)n1C +O=C(NCCNC(=O)C1CC1)c1cccc(Cl)c1Cl +Cc1cccc(C(=O)NCCC(O)c2cccs2)c1 +Cc1ccc(-c2nnn(-c3ccccc3)c2N)cc1C +O=c1cc(-c2ccc(F)cc2)ncn1C1CCCC1 +CCCc1cc(=O)[nH]c(Nc2nc(C)c3ccc(OC)cc3n2)n1 +c1ccc2[nH]c(CNc3ncnc4sccc34)nc2c1 +CC1(C)Cc2c(c(-c3ccccc3Cl)[nH]c(=O)c2C#N)CO1 +CCn1cc(CNS(=O)(=O)c2ccc(Cl)cc2)cn1 +CC(C)Oc1ccccc1CNC(=O)c1ccc2ncnn2c1 +CC(=O)c1cc2ccc3c(c2oc1=O)CN(C1CC1)CO3 +CN(C(=O)Cc1noc2ccc(N)cc12)c1ccccc1 +Cc1cccc(Cn2cc(NC(=O)c3sccc3C)cn2)c1 +O=C(CNc1ccc(F)c(Cl)c1)N1CCCCCC1 +CCn1cnnc1CCNC(=O)Nc1cccc(OC)c1 +CC(C)S(=O)(=O)c1ccc(CC(=O)NCC2(CO)CC2)cc1 +Cn1cc(-c2cccc(CNC(=O)C(O)c3ccccc3)c2)cn1 +CN(C(=O)c1csc(C2CCCO2)n1)C(CO)C(C)(C)C +CCCCN(C)C(=O)NCc1ccc(S(C)(=O)=O)cc1 +CCN(CC)C(=O)CN1CCN(c2ncnc3c2cnn3C)CC1 +CN1C(=O)CC(C(=O)NCCCC2CCCC2)C1c1cccnc1 +O=C1CCCN1c1ccc(OCc2cn3cc(Cl)ccc3n2)cc1 +O=C1CC(C(=O)OCCCc2cccnc2)c2ccccc2N1 +CC(C)Oc1ncccc1CNC(=O)c1c[nH]nn1 +O=C(NCCC(=O)N1CCCC1C1CCCC1)c1ccsc1 +CC(C)COCC(NC(=O)Nc1ccncc1)c1ccco1 +CCCOC(=O)c1ccc(-n2nnc(C#N)c2COC)cc1 +COc1cccc(C(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)c1 +O=C(CCn1cnc2ccccc2c1=O)NCC1CC2CCC1C2 +CC(C)CCOC(C)C(=O)N1CC(C)C(N2CCOCC2)C1 +CCCCNC(=O)CNc1ccc(C(=O)N2CCCCC2)cc1 +CCOc1cc2c(cc1NC(=O)C(C)OCC(F)(F)F)OC(C)C2 +CC(C)CNC(=O)NCCNC(=O)OC(C)(C)C +COC(=O)C(C)CN(C)S(=O)(=O)c1ccc(C#N)cc1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(C(N)=O)c(Cl)c1 +Nc1ccc2c(c1)N(C(=O)c1c(F)cccc1Cl)CC2 +CCNS(=O)(=O)c1cccnc1Nc1ccccc1F +CCc1ccc(S(=O)(=O)N(C)c2cccc(O)c2)cc1 +O=C1CCOCCN1Cc1ccc(Cl)c(Cl)c1 +COc1ccc(OC)c(C(C)NC(=O)NCCc2cnn(C)c2)c1 +CCOC(=O)C(C)NS(=O)(=O)c1ccc(C(C)(C)C)cc1 +Cc1noc(C)c1CCCNC(=O)Nc1cnn(CC2CCCO2)c1 +CC(Oc1ccc(F)c(F)c1)C(=O)N(C)CC(N)=O +Fc1cccc(Br)c1CN1CCOCC1 +CCc1ccc(NC(=O)c2ccc(F)c(F)c2F)cc1N +CCOC(=O)N1CCC(NC(=O)Cc2ccc(OCC)cc2)CC1 +Cc1noc(COC(=O)C(C)Sc2ncccn2)n1 +Cn1nc2n(c1=O)CCN(Cc1cc(Br)ccc1F)C2 +OCCC1CCCCN1c1nc(-c2cccnc2)nc2ccccc12 +CCN1CCN(C(=O)c2c[nH]c(C(C)C)n2)c2ccccc21 +CC(C)n1c(=O)[nH]c2cc(-c3noc(-c4ccncc4)n3)ccc21 +CCN(C1CCCCC1)S(=O)(=O)c1ccc(OC)c(OC)c1 +CCCc1noc(CNc2ccccc2CN2CC(C)OC(C)C2)n1 +CC1CCN(C(=O)C(C)Nc2cccc(CO)c2)CC1 +CCc1ccc(S(=O)(=O)NCCNC(C)=O)cc1N +O=C(CN1CCCCCC1=O)Nc1ccnn1CCc1ccccc1 +Cn1nc(C(=O)Nc2ccc3c(c2)NC(=O)CS3)ccc1=O +CC(C)NC(=O)Cc1cc(-c2ccc3c(c2)OCO3)on1 +Cc1cc(C)cc(CCNC(=O)c2ccc(S(C)=O)cc2)c1 +O=C1CCN(Cc2ccc(S(=O)(=O)C(F)F)cc2)CCN1 +CSc1ccc(CN(C)C(=O)c2cnn(-c3ccccc3)c2)cc1 +COc1ccc(-c2nnc(NC(=O)c3ccccc3OC)o2)cc1 +CC(=O)c1cccc(NC(=O)c2c(C)oc3nc[nH]c(=O)c23)c1 +CCNC(=O)c1snc(-c2ccc(OC)c(OC)c2)c1N +COc1cc(-c2c(C)c(C)nc3ncnc(N)c23)cc(OC)c1OC +O=C(Nc1ccccc1)N1CCOC(c2ccccc2)C1 +Cc1cc(NC(=O)COC(=O)C(C)(C)c2ccccc2)no1 +CCS(=O)(=O)NCCNc1ccc(C(F)(F)F)cn1 +O=C(Cc1ccsc1)NCCNC(=O)c1ccnc2cccnc12 +CNC(=O)NCC(=O)N1CC(C)OC(c2ccsc2)C1 +CCc1c(C(=O)Nc2cccc(C)n2)cnn1-c1ccc(C)cc1 +CN(CCOCc1ccccc1)C(=O)c1cscn1 +CN(CC1CCOCC1)C(=O)c1cc(COc2ccccc2)on1 +O=C(c1cncs1)N1CCC(Cc2nccs2)CC1 +CN(C)c1cc(N(C)Cc2cnc(N)nc2)ncn1 +CCc1onc(C)c1NC(=O)NCc1ccccc1Cn1cccn1 +Cc1ccc(OCC#CCNC(=O)CCn2ccc(=O)[nH]c2=O)cn1 +Cc1noc(C)c1C(C)CC(=O)N=c1[nH]c2cc(F)ccc2n1C +NC(=O)C1(CCCc2cccnc2)CCCN(c2cnccn2)C1 +Cc1noc(C)c1S(=O)(=O)N(C)c1ccc(N)cc1F +Cc1cc(C)n(CCCNC(=O)CCn2nc(C)c3ccccc32)n1 +O=C(CNC(=O)NC1CCCCC1)N=c1[nH]c2ccccc2[nH]1 +Cc1nc(C)c(CCNC(=O)Cc2ccc(F)cc2F)s1 +CC(NC(=O)OC(C)(C)C)C(=O)N(C)Cc1cscn1 +O=C(c1ccc(F)cc1)N1CCc2sccc2C1C1CC1 +CC(=O)c1cnnc(-c2ccc(Br)cc2)n1 +COCCOc1cc(NC2CC2)nc(C(C)(C)C)n1 +CCc1nc(CN2CC(CC(C)C)CC2=O)cs1 +Cc1occc1C(=O)Nc1cnn(Cc2ccc(F)cc2)c1 +O=C(Nc1ccc(F)cn1)c1[nH]ncc1Br +O=C(CNC(=O)N(Cc1ccccc1)Cc1ccco1)N1CCCC1 +Cc1cccnc1NC(=O)c1cnn(-c2cccc(Cl)c2)c1C +CC1CCCN(C(=O)c2ccc(N)cc2Cl)C1C +O=C(Nc1ccn(-c2ncccc2Cl)n1)C1CC1(Cl)Cl +Cn1cccc(NC(=O)c2cccc(-n3cnnn3)c2)c1=O +O=C(Nc1ccc2c(c1)oc1ccccc12)c1cccnc1 +O=C(NCCc1ccsc1)c1ccc2ccccc2n1 +O=C(c1ccc(CSc2nc3ccccc3[nH]2)cc1)N1CCCC1 +CC1CCN(C(=O)C(C)Sc2nnc(-c3ccncc3)o2)CC1 +COc1cccc(C(=O)N(Cc2ccco2)Cc2ccco2)c1F +O=S(=O)(c1ccc(F)c(F)c1)N1CCN(c2ccccc2)CC1 +COc1ccc(N)cc1CNC(=O)c1cnn(C)c1 +Cn1c(COc2cccc3ccccc23)cc(=O)n(C)c1=O +Cc1ccc(CC(=O)N2CCC(C(=O)N3CCCC3)CC2)cn1 +COCCCNS(=O)(=O)c1ccc(NC(C)=O)cc1 +Cc1nnc(N2CCCC2c2ccsc2)c(C#N)c1C +Cc1ncc(CN(CCC(N)=O)Cc2ccccc2)s1 +CCC(C)C(=O)Nc1cc(C(=O)NC(C)C)ccc1Cl +CCc1ccc(C(C)NS(=O)(=O)C(C)C)cc1 +O=C(CNC(=O)c1ccsc1)NCC1(O)CCCCCC1 +CCOc1ccc(C2(CNC(=O)NCCO)CCOCC2)cc1 +CCNC(=O)CCC(=O)Nc1cc(OC)ccc1F +COCCCSc1nc(-c2ccccc2Br)n[nH]1 +COc1ccccc1Cc1nc2c(N)cccn2n1 +COC(=O)C(Oc1ccc2ccc(=O)oc2c1)c1ccccc1 +CC1CCCN(S(=O)(=O)NCCCCn2ccccc2=O)C1 +CCCN(CCC)C(=O)CN(C)c1ncnc2[nH]cnc12 +COc1ccccc1COC(=O)c1c(C)cc(=O)oc1C +C=CCNc1ncnc2sc(C(=O)N3CCC(C)CC3)c(C)c12 +COc1ccc2c(c1)C(=O)C(=O)N2CCC(=O)c1ccc(F)cc1 +CC(c1cccs1)N(C)Cc1nc2c(cnn2C)c(=O)[nH]1 +COc1cc(OC)c(-c2n[nH]c(C)c2N)c(OC)c1 +CCOC(=O)C(Sc1ncn[nH]1)c1ccccc1 +COCCNc1ncnc2scc(-c3ccc(F)cc3)c12 +COc1ccc2nc(Cc3c[nH]c4ccccc34)[nH]c(=O)c2c1 +Cn1cc(S(=O)(=O)NCCOCC(F)(F)F)cn1 +Cc1cc(N)nc(SCC(=O)N2c3ccccc3CC2C)n1 +CCN(Cc1cc(F)ccc1F)c1cccc(N)c1 +Cc1c(C(=O)Nc2cccc(-n3cnnc3)c2)cnn1-c1ccncc1 +Cc1cccc(C)c1OS(=O)(=O)c1c(C)noc1C +CCOc1ccc(-c2ccc(C(N)=O)c(N)n2)cc1Cl +COc1ccc(CN(C(=O)Nc2ccncc2)C(C)C2CC2)cc1 +COc1cccc(NC(=O)NCCC(O)C(C)(C)C)c1OC +N#Cc1cccc(C(=O)Nc2ccc(NC(=O)C3CCCO3)cc2)c1 +CN(c1ccc(F)c(F)c1)S(=O)(=O)c1cccc(C(N)=O)c1 +CCOC(=O)Nc1cc(C(=O)OC)cc(C(=O)OC)c1 +O=C(c1ccnnc1)N1CCC2OC(COc3cccnc3)CCC21 +CCS(=O)(=O)NC(C#N)c1cc(OC)ccc1OC +O=C(Nc1ccon1)C1(c2cc(-c3cccs3)on2)CC1 +CCOc1ccc(CCNCc2cncnc2)cc1 +O=C(CSc1nc(C2CC2)nc2ccccc12)Nc1nccs1 +Cc1c(-c2ccncc2)n[nH]c1NC(=O)c1cc2ccccc2n1C +O=C(c1ccc(CNc2nc3ccccc3o2)cc1)N1CCCCC1 +[H]N=c1c(C#N)c(C)c(C(=O)OCC)nn1-c1ccccc1 +Cc1nnc(NC(=O)NC2CCN(c3ncccn3)CC2)s1 +CCN(C1CCCC1)S(=O)(=O)c1cn[nH]c1C +CC(C)(C)NC(=O)NCC1OCCc2sccc21 +Cc1ccc(OC(C)C(=O)Nc2ncccn2)cc1 +COc1ccc(CN(C)C(=O)c2c[nH]c3cccc(F)c23)cc1C +CC(Cn1cc(Cl)c(=O)[nH]c1=O)c1ccccc1 +CC=Cc1cc(C(=O)N2CCC3(CC2)OCCO3)cc(OC)c1OC +Cc1ccc(OS(=O)(=O)c2ccc(N3CCCC3=O)cc2)cc1 +O=C(COc1ccccn1)Nc1ccc(Br)cc1F +N#Cc1c[nH]c(C(=O)NC2CCN(c3c(F)cccc3F)C2=O)c1 +CCNC(=O)c1snc(S(=O)(=O)C2CC2)c1N +COc1ccc(C(=O)Nc2nccs2)cc1OC +CCC(C#N)C(=O)N(C)C(C)c1ccccc1Cl +CC1C(=O)NCCN1C(=O)COc1ccccc1Cl +CCCNC(=O)CSc1nc(-c2ccco2)nc2ccccc12 +COc1cc(-c2noc(-c3ccc4cc[nH]c4c3)n2)ccn1 +COc1cc2c(CC(N)=O)cn(C)c2cc1Cl +CCNC(=O)Nc1ccc2c(c1)CCN2S(C)(=O)=O +Cc1ccn(-c2ccccc2NCc2cc3ccccc3[nH]c2=O)n1 +COc1ccccc1-c1cc(C)n(C(C)C)c(=O)c1C#N +Cc1c(C(=O)N(C)C(C)Cc2ccsc2)cnn1-c1ccncc1 +Cc1ccccc1CN1CCN(S(=O)(=O)N2CCOCC2)CC1 +Cc1cnn(CCC(=O)Nc2nc(-c3cc(F)ccc3F)cs2)c1 +CCn1c(SCC(C)C)nnc1N1CCOCC1 +CCn1cc(CN2CCN(C(=O)Cc3cccc(OC)c3)CC2)cn1 +O=C(NCCCOc1ccc(F)cc1)c1cc2cccnn2c1 +COc1cc(C)c(Nc2c(C#N)c(=O)n(C)c(=O)n2C)cc1OC +CCC(C)Nc1nnc(-c2scnc2C)s1 +CC(C)c1nnc(CNC(=O)c2cnn(C(C)(C)C)c2)s1 +Cn1c(=O)n(C)c2cc(NC(=O)CCSc3ccccc3)ccc21 +CC(NC(=O)N(C)C(C)C1CC1)c1cnn(C)c1 +O=C(Nc1cccc(SC(F)F)c1)c1ccc(-n2ccnn2)cc1 +COc1ccc2cc(C(=O)NCCc3ccco3)n(C)c2c1 +Cc1ccnc(NC(=O)c2cc3c(s2)CCCC3)c1 +CC(NC(=O)c1ccc(CNC(N)=O)cc1)c1cc2ccccc2o1 +CC(=O)NCc1ccc(C(=O)Nc2ccccc2S(C)(=O)=O)cc1 +COC(=O)CN1C(=O)N2CCCN=C2c2ccc(Cl)cc21 +CC(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +O=C(Nc1ccc(C(=O)N2CCCCC2)cc1)c1ccc(F)cc1 +CNC(=O)C(NC(=O)c1ncoc1C)c1ccccc1 +Cn1cc(CNC(=O)c2cc(-c3cccc(Cl)c3)on2)cn1 +CCn1c(SCCCC#N)nc2cc3ccccc3cc2c1=O +Cc1cccc(CC(=O)N2CCCC2c2nc(C3CC3)no2)c1 +Cc1sc(-n2cnnn2)c(C(=O)Nc2ccccc2)c1C +N#Cc1cccc(N2CCCC(CO)(CCc3ccccc3)C2)n1 +CCOc1nc(N(CCOC)C2CC2)ccc1N +CCC(C)NC(=O)c1cc(-c2ccccc2F)no1 +CCc1cccc(CC)c1NC(=O)c1c(C)cccc1N +Cc1nn(C)c(=O)c(C(=O)Oc2cccc(Br)c2)c1C +O=C(CSc1ccncc1)NCc1ccnc(OC2CCC2)c1 +CCOC(C)c1noc(CNc2ccc(C)cc2)n1 +Cc1cc(C(=O)N2CCCC(C)CC2)c2c(=O)[nH]n(C)c2n1 +Cc1cnc(C(=O)Nc2nc(-c3cccs3)cs2)cn1 +COc1cc(Br)cn(CCCC#N)c1=O +CC(=O)n1nc(-c2ccc(C)cc2)nc1NCc1ccco1 +CCC1(C)Nc2cc(Cl)ccc2N(CCC#N)C1=O +CC(C)Oc1ncccc1NC(=O)NCC(C)(O)c1ccc(F)cc1 +Cc1c(C(=O)NCc2cnn(-c3ccccc3)c2)[nH]c2c1C(=O)CCC2 +CC1(C)CC(=O)c2cc(C(=O)N3CCC3)c(=O)[nH]c2C1 +COc1ccccc1Nc1cc(-n2ncc(C(C)=O)c2C)ncn1 +COc1cc(C(=O)N2CCCCC2CCO)on1 +CC1=CC(C)(C)N2C(=O)C(=O)c3c4c(cc1c32)CCC4 +CC1CCC(NC(=O)Cn2nnc(-c3ccco3)n2)CC1 +CCN(C)C(C(=O)NCc1cn(-c2ccccc2)nn1)c1ccccc1 +COc1ccc(S(=O)(=O)NCc2ccccn2)c2nonc12 +Cc1noc(CCNC(=O)NCc2ccnc(OC(C)(C)C)c2)n1 +Cc1ccc(S(=O)(=O)CCC(=O)Oc2ccccc2)cc1 +Cc1cccc(NC(=O)c2ccc(Cl)c(S(N)(=O)=O)c2)c1C +Cc1cccc(Nc2nc(C(=O)NCC(N)=O)cs2)c1 +CCc1nc(CCNC(=O)CCc2ccccc2O)sc1C +COCCCNC(=O)CN1CCN(c2ccc(O)cc2)CC1 +CCc1cc(C(=O)Nc2ccc(F)cc2F)no1 +CN(CCc1cccc(Cl)c1)C(=O)c1ccccc1N +CC(Sc1n[nH]c(N)n1)C(=O)c1ccc2c(c1)n(C)c(=O)n2C +NS(=O)(=O)c1cc(-c2nc(-c3ccsc3)no2)cs1 +OCCOc1cccc(CN2CC(Oc3ccccc3Cl)C2)c1 +CNC(=O)CCCN(C)Cc1nc2c(s1)CC(C)CC2 +CCC(C)NC(=O)COC(=O)c1c(NC(C)=O)sc(C)c1C +CCc1ccc(NC(=O)Cn2cc(Cl)c(=O)[nH]c2=O)cc1 +COc1ccc(NC(=O)CCCc2nc(C)no2)cc1 +Cc1ccc(C(=O)OCc2nc(N)c3ccccc3n2)o1 +Cc1cc(NC(=O)c2cccc(Oc3ccccc3)c2)n(C)n1 +CCc1nsc(N2CCCN(C(=O)CCc3ccco3)CC2)n1 +Cc1ccccc1Cn1nnc(-c2cccnc2)n1 +COc1ccc(CCNc2ncccc2F)c(OC)c1OC +COc1cccc(OC)c1OCC(=O)Nc1cc(C)on1 +CCOC(=O)c1cc(C(=O)Nc2ccc(C)c(F)c2)nn1C +Nc1cccc(Cn2c(C3CC3)nc3cc(N)ccc32)c1 +O=C(NCc1ccccc1Cl)C1CCCN1C(=O)C1CCCCC1 +O=c1cnn(Cc2c(Cl)cccc2Cl)c2ccccc12 +CNC(=O)CC1CCN(C(=O)NCc2cc(C(C)C)no2)CC1 +Cc1nn(CC(=O)Nc2ccc(Cl)cn2)c(C)c1N +Cn1cc(C2CCCN2CC(O)CN2CCOCC2)cn1 +CNC(=O)c1ccccc1NC(=O)c1ccc(Cl)cc1Cl +CCc1noc(CC)c1CNC(=O)CCC1CCCC1 +O=C(CSc1ccc(F)cc1)OCC1CCCO1 +CCNC(=O)c1cccc(CNS(C)(=O)=O)c1 +Cn1nnn(-c2ccc(NC(=O)NC3CCCCC3)cc2)c1=O +Cc1ccc(OCCN(C)C(=O)c2ccc3cc[nH]c3c2)cc1 +O=C(c1ccccc1)c1cnc(N2CCOCC2)s1 +COc1cc(C)ccc1OCC(=O)Nc1ccc(C(C)=O)cc1 +COc1ccc(-c2n[nH]c(SCC(=O)NCC(C)C)n2)cc1 +CC(NS(=O)(=O)N(C)CCC#N)c1ccccc1C(F)(F)F +CC(=O)N1CCCC1c1ccnc(Nc2ccccn2)n1 +Cc1nn(C)c2nc(N)c(C(=O)NCCCOC(C)C)cc12 +N#Cc1cccc(NC(=O)c2cc3c(s2)CCC3)c1 +CCOC(=O)c1c[nH]nc1NC(=O)Nc1cccc2ccccc12 +CCC(C)(C)NC(=O)CS(=O)(=O)c1ccc(OC)cc1 +C=CCN(Cc1ccccc1F)C(=O)NC1CCN(C(=O)OC)CC1 +Cn1ccnc1C(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +O=C(NCc1ccccc1F)C1COc2ccc(F)cc2C1 +COCCOc1cccc(C(=O)NC(C)c2cc(C)sc2C)c1 +O=C(c1cc2c(F)cccc2[nH]1)N1CCN(c2cnccn2)CC1 +CC(C)CN(CCC#N)C(=O)c1ccc(Br)cc1O +COCn1nc(CO)cc1-c1ccc(Cl)cc1 +COc1cc(-c2noc(-c3ccccc3)n2)cc(OC)c1OC +COCC1CCCN(C(=O)c2cccc(OC)c2)C1 +Cc1cc(NC(=O)C(NCCc2cccs2)c2ccccc2)no1 +Cc1cnn(CC2CN(Cc3ccccc3OC(C)C)CCO2)c1 +O=C(Cc1ccc[nH]1)N1CCOC(c2ccccc2Br)C1 +CCn1c(C)cc(C(=O)Nc2cccc(OC(F)F)c2)c1C +Cc1ccnc(N2CCN(Cc3ccc4c(c3)OCO4)C(=O)C2)n1 +Cc1c(C(=O)NCc2ccc(NC(N)=O)cc2)oc2ccccc12 +COc1ccc(C(=O)NC2=NC(=O)CC3C(=O)NCCN23)cc1 +CCOC(=O)CCCSc1nnc2sc3ccccc3n12 +O=C(NCC#CCOc1cccnc1)c1cncc(Br)c1 +O=C(Cn1cnc2ccccc2c1=O)NCCCN1CCOCC1 +CC(=O)c1c[nH]c(C(=O)Nc2ccc3c(c2)COC3)c1 +Oc1cccc2c(NCc3cncnc3)cccc12 +CC(C#N)Sc1nnc(C(C)Oc2ccccc2F)o1 +CCN1CCN(C(=O)CC(C#N)c2cccs2)CC1 +N#CCCn1c(-c2ccccc2)nc2cc(Cl)cnc21 +CC1CN(CC(=O)Nc2ccc(N3CCCCC3)nc2)CC(C)O1 +Nc1cccc2cc(C(=O)N(CCO)C3CC3)[nH]c12 +Cc1nn(C)cc1C(=O)N1CCC(c2cc3ncccc3cn2)CC1 +C=C(c1ccccc1)C1NCCc2ccc(NC(C)=O)cc21 +Cc1nn(C)c(C(=O)NC(C)c2cccc(-n3cccc3)c2)c1Cl +O=C(NCCO)NCc1ccc(Oc2cccnc2)c(F)c1 +CC(C)Cn1cc(NCc2cc(F)cc3cccnc23)cn1 +O=C1CC(c2ccco2)c2c(c3ccccc3[nH]c2=O)O1 +COc1cccc(NC(=O)C2CCCN2S(C)(=O)=O)c1 +O=C(c1cn2cc(Cl)ccc2n1)N1CCN(c2ncccn2)CC1 +C=CCOC(=O)C1=C(C)Nc2ncnn2C1c1ccccc1 +CC(C)C(C)NC(=O)CCc1nc2ccccc2s1 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)C1CCCCC1 +CC(COc1ccc(F)cc1F)NS(=O)(=O)c1ccccc1F +Cc1noc(C2CCN(C(=O)c3cccc4c3OCCO4)CC2)n1 +C=CCNc1nnc(SCC(=O)c2ccccc2F)s1 +COC(=O)CNC(=O)C(N)c1cc(C)ccc1C +CC(C)c1cnn2c(=O)cc(-c3ccccc3)[nH]c12 +COc1nn(C)cc1C(=O)NCC(OC)c1ccccc1C +CC(=O)N1CCCC1C1NCCc2c(C)cc(F)cc21 +CCCOc1cccc(C(=O)NCc2cccc(S(N)(=O)=O)c2)c1 +CC(=O)Nc1ccc(O)c(C(=O)N(C)Cc2ccc(F)cc2)c1 +O=C(Nc1nc2c(c(=O)[nH]1)CCCC2)c1cccs1 +N#CCCN(CCC(F)(F)F)Cc1cccc2cn[nH]c12 +COC(=O)c1ccc(OCC(=O)C2=NC=CC2)cc1 +C=CCN(Cc1ccccc1)Cc1scnc1C +NC(=O)C1(c2ccccc2)CCN(C(=O)CN2CCCC2=O)CC1 +Cn1cccc(NC(=O)c2cc(Br)ccc2Cl)c1=O +CCC1Oc2ccccc2N(CC(=O)NCCC(C)C)C1=O +Cc1ccc2nc(C)c(C(=O)NC3CCc4nnc(C)n4C3)cc2c1 +C=CCNC(=O)c1ccc(S(=O)(=O)Nc2cccc(C)c2C)cc1 +Cc1c(N)ccc2nnc(-c3ccccc3Br)n12 +CCC(NCc1noc(C2CC2)n1)c1c(C)noc1C +CCS(=O)(=O)N1CCOC(c2ccccc2Cl)C1 +CCC(=O)N1CCCc2cc(NC(=O)c3cccc(F)c3)ccc21 +Cc1ocnc1CNS(=O)(=O)c1ccccc1S(C)(=O)=O +O=C1CCC(C(=O)OCc2nc3ccccc3n2C(F)F)CN1 +Cc1cccc(NC(=O)COC(=O)c2cncc(Br)c2)c1 +CCOC(C)c1noc(-c2ccc3c(c2)CCO3)n1 +O=S(=O)(NCc1nccs1)N1CCc2ccccc2C1 +Brc1cccc(-c2nccn2CCN2CCOCC2)c1 +CCN(CC)C(=O)c1ccc(Cl)c(NC(=O)c2ccccc2F)c1 +O=C(OCC1CC(=O)N(C2CC2)C1)C1COc2ccccc21 +CCC(Oc1ccccc1OC)C(=O)Nc1ccc(C(N)=O)cc1 +CNC(=O)c1ccc(Nc2ncnc3sccc23)cc1 +CCC(C)Nc1ncnc2c1cnn2-c1ccccn1 +COC(=O)C1NCC(C)c2c(SC)cccc21 +Cn1cc(C(=O)Nc2ccc(Cl)c(C#N)c2)c(-c2cccs2)n1 +COC(=O)c1sc(-c2ccc(OC)cc2OC)nc1C +Cc1nn(C)c(=O)c(C(=O)N(C)CCOc2ccc(F)cc2)c1C +O=C(Nc1ccc(S(=O)(=O)C2CCCC2)cc1)c1ccccn1 +CN(CC(=O)Nc1ccc(O)cc1)C(=O)c1c[nH]c2ccccc12 +CCOc1cc(S(=O)(=O)n2ccnc2CC)c(C)cc1C +CC(=O)c1cc(Br)c2c(c1)N(C)C(=O)CO2 +COc1ccc(C(=O)NCCC(=O)NCc2cccnc2)c(O)c1 +CCOC(=O)N1CCC(c2nnc(-c3ccco3)s2)CC1 +O=C(Nc1ccc(F)cc1F)C1CNc2ccccc2O1 +Cc1cc(C)n(C(C)CC(=O)NCc2ccccc2-n2ccnc2)n1 +COCc1ccc(CNC(=O)NCC(C)(O)c2ccco2)cc1F +CCCN(CCO)C(=O)Nc1ccc(C(=O)NC2CCCC2)cc1C +CCNc1ccnc(N2CCCN(S(C)(=O)=O)CC2)n1 +CC(=O)N1CCCC(c2ccc(-c3cccc(CO)c3)cn2)C1 +CS(=O)(=O)Nc1cccc(C(=O)N2CCCCCC2)c1 +CC(NC(N)=O)C(=O)NC(C#N)c1ccc(C(C)(C)C)cc1 +CNC(=O)c1ccc(-n2nc(C)c(-c3ccccc3)c2NC(C)=O)cc1 +COc1cc(C#N)ccc1OCC(=O)Nc1ccc(-n2ccnc2)cc1 +COc1cc(Cl)ccc1CNC(=O)N1CCCC(O)C1 +CCn1nnc(NC(=O)COc2cccc(C)c2)n1 +O=C(NCc1n[nH]c(=O)[nH]1)c1cccc(OCC(F)F)n1 +Cc1csc2nc(-c3cccc(NC(=O)C(C)C)c3)cn12 +Cc1c(C(=O)Nc2cccc3c2ccn3C)sc2nc[nH]c(=O)c12 +CC(C)OC(=O)CN1C(=O)C(C)Oc2cccc(N)c21 +CC(C)n1nccc1NC(=O)CCC(=O)c1ccc(F)cc1 +O=C(Cc1nc(-c2cc3ccccc3o2)cs1)N1CCOCC1 +CCC(CC)C(=O)N1CCN(Cc2noc3ccccc23)CC1 +COc1ccccc1C(=O)Nc1ccccc1Cn1cccn1 +O=C(NCc1ccco1)c1nc(-c2cccs2)no1 +COc1ccc2c(cnn2CCC(=O)Nc2c(C)noc2C)c1 +CC(C)c1ncc(Cl)c(C(=O)NCc2ccc(F)cc2)n1 +O=C(Cn1c(=O)oc2ccccc21)Oc1ccc(F)cc1 +CC(C)(C)n1ccc2c(cnc3nc(-c4ccccc4)nn32)c1=O +CC(C)(C)OC(=O)N1CCCCC1COCc1cncs1 +Cc1ccc(CN2CC(C(=O)NCc3ccccn3)CC2=O)cc1 +CC(C(O)c1ccccc1)N(C)C(=O)c1ccccc1Br +COc1cc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc(OC)c1 +CN(C)C(=O)COc1ccc(NC(=O)CC2CCCC2)cc1 +Cc1cc(NC(=O)NCc2cccc(C)n2)c2ncccc2c1 +CN(CCCc1nc2ccccc2[nH]1)C(=O)c1nccc2ccccc12 +Cc1cccc(CN(Cc2ccccn2)C(=O)COC2CCCC2)c1 +Cc1nnc(SCC(=O)NCCCc2c(C)n[nH]c2C)s1 +c1ccc(CN2CC(OCCCn3cccn3)C3OCCCC32)nc1 +CCN(CCCNC(=O)c1cc2ccccn2c1)S(C)(=O)=O +Cc1ccc(OCCC(=O)Nc2ccccn2)c(C)c1 +COc1cc(C)c(S(=O)(=O)Nc2ccccn2)cc1C(C)C +CSc1ccc2c(c1)CCN(C(=O)Nc1nc(C)ns1)C2 +COc1cc(CCC(=O)N2CCC(CC(N)=O)CC2)cc(OC)c1 +O=C(Nc1nnc(C2CCCCC2)o1)c1c[nH]c2ccccc12 +CC(=O)c1cccc(OC(C)C(=O)NCCc2nc(C)cs2)c1 +CC(C)CNC(=O)C1CCCN1C(=O)c1cccs1 +CN(CC(=O)OCc1cc2ccccc2[nH]c1=O)Cc1ccccc1 +O=C1Cc2cc(NC(=O)Nc3cccc(Br)c3)ccc2N1 +COc1cc2c(cc1OC)C(C)N(C(=O)c1ccc(N)cc1)CC2 +Cc1ccc(CNC(=O)C2CCN(C(=O)OCC(C)C)CC2)cn1 +CC(C)(C)C(=O)NCCC(=O)NCc1ccc(-n2ccnc2)cc1 +Cc1nc(NC(=O)c2cc(OCc3ccccc3)no2)sc1C +NC(=O)c1ccsc1NC(=O)Cc1ccc(Br)cc1 +c1nc(OCC2CCCO2)c2c3c(sc2n1)CCC3 +Cc1ccc(S(=O)(=O)NCC2CCCC2)c2c1NCCC2 +CCC1CN(C(=O)c2cc(Cl)c3c(c2)OCO3)CCO1 +Cc1ccnc(N2CCc3c(c(C(N)=O)nn3C)C2)n1 +Cc1ccccc1-n1nccc1NC(=O)C(C)c1c(C)nn(C)c1C +NC(=O)c1ccc(C(=O)N(CC(F)F)C2CC2)cc1 +c1cncc(CN(Cc2nc3c(s2)CCC3)CC2CCCO2)c1 +CCOc1ccc(NC(=O)c2ccccc2OCC(N)=O)c(C)c1 +Cn1c(SC2CCOC2=O)nnc1-c1ccccc1F +Cc1nonc1OCCNC(=O)c1cc2sccc2[nH]1 +CC(C)Cc1cc(C(=O)N(C)CC2Cc3ccccc3O2)no1 +O=C(CSc1ncn[nH]1)Nc1cc(C(F)(F)F)ccc1Cl +COc1ccccc1C(=O)NCC(=O)N1CCC2CCCCC2C1 +CCC(O)CN1CCN(C(=O)C2CC2c2cccc(F)c2)CC1 +N#Cc1ccc(C(=O)CSc2n[nH]c(=O)[nH]c2=O)cc1 +CC(C)CCN1C(=O)C(C)(C)C(=O)c2ccc(N)cc21 +COc1ccc(NC(=O)CN(C)C(=O)c2cc3ccccc3o2)cc1 +Cc1cc(C(=O)N2CCC(NS(C)(=O)=O)CC2)n[nH]1 +O=S(=O)(C1CC1)N1CCC(c2nc(C3CC3)no2)C1 +COc1cc(C)ccc1NC(=O)NCCc1ccsc1 +O=C(C1COc2ccccc2C1)N1CCC(Nc2cccnc2)CC1 +Cc1sc(=O)n(CC(=O)NCCOc2ccccc2)c1C +CC1CC(=O)Nc2ccccc2N1C(=O)C1CCCOC1 +O=C(Oc1ccc(-n2cnnn2)cc1)c1cc(F)ccc1F +CN(C)C(=O)C(c1ccccc1)N1CCC(c2ccnn2C)CC1 +Cc1cc(C(C)NC(=O)NCCC(=O)N2CCCC2)c(C)s1 +N#Cc1ccc(OCC(=O)NCc2ccc(-n3ccnc3)cc2)cc1 +O=S(=O)(N1CCOCC1)N1CCN(Cc2ccco2)CC1 +Clc1ccccc1OCc1nc2c(s1)CCN2 +O=C(Nc1cccc(COCC(F)(F)C(F)F)c1)c1ccco1 +Cc1nn(C)cc1CCC(=O)N(C)c1ccccc1C(=O)OC(C)C +COc1cccc(C2CCCN2C(=O)c2cc(C)on2)c1 +O=C(NCc1ccc(-n2cccn2)nc1)Nn1cnc2ccccc21 +Cc1n[nH]c(C)c1CNC(=O)CCn1ccc2cc(Cl)ccc21 +CSc1ncc(CO)c(Oc2ccc(C)cc2)n1 +CCc1cc(C#N)c(NC(=O)CCC(=O)N(CC)CC)s1 +O=C(Cc1ccccn1)N1CCC2(CCCN(c3ncccn3)C2)C1 +Cc1cc(C)c(C(=O)N2CCN(Cc3ccsc3)CC2)c(=O)[nH]1 +CC(C)(C)CC(=O)NCC(=O)NCCc1ccccn1 +Cc1ccc2[nH]nc(C(=O)NCCCN3CC(C)OC(C)C3)c2c1 +CC(=O)N1CCN(C(=O)c2cccc(OCc3ccccc3)c2)CC1 +CC(CO)CNC(=O)Nc1nc2ccccc2s1 +Cc1cc(NC(c2ccccc2)c2cccs2)n2ncnc2n1 +CCc1oc(C(=O)NCc2csc(=O)[nH]2)cc1C +COCCNS(=O)(=O)c1cccc(C(=O)C(C)C)c1 +COc1cccc(C(=O)Nc2ccccc2SCC(N)=O)c1 +COc1ccc(C(=O)N2CCC(c3nnc(C4CC4)o3)CC2)cc1 +CCOc1ncccc1CNC(=O)c1ccc(OC)c(OC)c1 +CCN(Cc1ccccc1)C(=O)CNS(=O)(=O)N(C)C +Cc1ccc(SCC(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1 +c1cnn(-c2ccc(CN3CCN(c4nccs4)CC3)cc2)c1 +O=C(Nc1ncccc1O)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +CC(C)n1cnnc1C1CCN(C(=O)c2cnn3cccnc23)CC1 +CNc1ccc(S(=O)(=O)NCc2cnc(C)s2)cc1 +COc1cccc(NC(=O)N2CCC(n3cc(C)cn3)CC2)c1 +C#Cc1cccc(NC(=O)c2nc3nccc(C)n3n2)c1 +CCCOc1cccc(-c2nc(N)nc(C)c2C(N)=O)c1 +Cc1ccc(C(=O)N2CCc3[nH]ncc3C2)cc1Oc1ccncc1 +COCC(=O)Nc1ccc(NC(C)COC)cc1 +NC(c1ccc(Cl)cc1)c1nc(-c2ccco2)n[nH]1 +COc1ccc(O)c(C(=O)N2CCN(Cc3csc(C)n3)CC2)c1 +CS(=O)(=O)c1cccc(NC(=O)COc2ccc3c(c2)CCC3)c1 +COc1ccc(-c2sc(C)nc2N)cc1C(C)C +CCn1c(=O)c(NCc2ccc(C)c(C)c2)nc2ccncc21 +CC(=O)Nc1ccc(CNC(=O)CNCc2sc(C)nc2C)cc1 +Cc1ccccc1CNC(=O)CCn1ncc2cccc(C)c21 +CCOC(=O)C(O)(NC(=O)c1ccccc1)C(F)(F)F +CCOC(=O)Cn1cc(Br)cc1C#N +O=C(c1cc[nH]n1)N(Cc1ccc(Cl)c(Cl)c1)C1CC1 +COC(=O)N1CCC(NC(=O)Nc2ccc(F)cc2C)CC1 +COc1ccc(CNc2ncc(N)cc2Br)cc1 +CCOCCC(=O)Nc1cccc(Cl)c1N(C)C +Cc1n[nH]c(C)c1NC(=O)c1ccc2c(c1)CCCC2 +CC(=O)N1CCCC(C(=O)NCc2noc(Cc3ccccc3)n2)C1 +CCc1nnc(-c2cc(NC(=O)c3ccc(OC)nc3)c(C)s2)o1 +Cc1cc(C)c(C(=O)Nc2cnn(CC(F)F)c2)c(C)c1 +O=C(Nc1ccc(Cl)cc1F)N1CCc2ccc(O)cc2C1 +COc1ccc(CCNC(=O)c2cccc(Cl)c2)cc1OC +O=C(Nc1cc(N2CCOCC2)ncn1)c1cc(C2CC2)on1 +CCOc1ccc(N2CCCC(CNC(=O)C(C)(C)C)C2)nn1 +COc1cc(C)c(-c2nn(C)c(C)c2N)cc1OC +CCOC(=O)c1nnn(-c2cccc(Cl)c2C)c1N +COC(=O)C1CN(Cc2nccn2CC(F)(F)F)c2ccccc21 +CCCC(=O)Nc1cccc(NC(=O)C2CC(=O)N(CC)C2)c1 +CCOC(=O)C(C)(C)C(O)c1ccc(F)c(Br)c1 +CCc1oc2ccccc2c1CN(C)C(=O)c1nccnc1N +Cc1ccccc1CC(=O)Nc1nc(C)c(C)s1 +CC(=O)NCCNC(=O)N(CC(C)C)CC(C)C +Cc1ccc(C(C)NS(=O)(=O)c2cccc(Br)c2)o1 +COC(=O)c1cc(CNC(=O)CN2CCCCC2=O)oc1C +C#Cc1cccc(N(C(=O)Cc2nc(-c3ccco3)oc2C)C(C)C)c1 +Cc1ccc2c(c1C)OC(C)(C)C(CN1CCOCC1)C2N +CC(C)NC(=O)CSc1nc(N)c2ccsc2n1 +CC1CN(CC(C)C(=O)c2ccccc2)CC(C)O1 +COC(=O)CNC(=O)C1CC(=O)N(Cc2ccc(OC)cc2)C1 +COc1cc(N)ccc1NC(=O)C(C)n1cncn1 +Cc1cc(NC(=O)Cc2c(F)cccc2Cl)sn1 +COC(=O)c1cccc(C(=O)N(C)c2ccccc2)c1 +CN(C)C(=O)CN(Cc1cccc2c1OC(C)(C)C2)CC(F)(F)F +COc1cccc(F)c1OCc1nc(COc2ccccc2)no1 +CC(=O)N1CCCN(C(=O)c2ccc(C)s2)CC1 +COC(=O)CCSc1nnnn1-c1ccc(C)cc1 +Cc1ccc(C(=O)N2CCN(C(=O)c3cnns3)CC2)cc1F +O=C(C1CCOCC1)N1CCOC2CCC1C2OCc1ccncc1 +NC(=O)c1csc(C(=O)Nc2ccc(Cl)c(Cl)c2)c1 +Cc1ccnc(NC(=O)CC(c2ccccc2C)n2cccc2)c1 +CCOC(C)c1noc(CN2C(C)COC(c3ccccc3)C2C)n1 +Cc1cccc(C)c1OC(=O)Cn1nnc2ccccc21 +CNc1ccc(F)c(NS(=O)(=O)c2ccc(C)cc2)c1 +COCCOc1ccc(NC(=O)c2cccnc2N(C)C)cn1 +Cc1cccc(C(=O)NC(C)C(=O)NCc2ncc[nH]2)c1 +COc1ccccc1-c1coc2cc(OCC#N)ccc2c1=O +O=S(=O)(N1CCOCC1)N1CCc2ccccc2C1 +Cn1c(C2CC(=O)N(c3ccc(Cl)cc3)C2)nc2ccccc21 +Cc1c(C(=O)N2CCC(CN3CCOCC3)CC2)cnn1C +CCCNC(=O)Cn1nc2c3ccc(Cl)cc3ncn2c1=O +CC(Cn1ccnc1)NC(=O)c1n[nH]c2ccccc12 +COc1cc(C)c(Cl)cc1C(=O)NCCCO +COC(=O)C1CCN(C(=O)c2ccc(NC(=O)C(C)C)cc2)CC1 +Cc1cccc(OCC(=O)N2CCN(Cc3ccccn3)CC2)c1 +O=C(Cc1cccs1)NC1CC(=O)N(CCc2ccccc2)C1 +CCCCNC(=O)CS(=O)(=O)c1ccc(O)cc1 +COc1nn(C)cc1C(=O)Nc1ccc(Cl)c(Cl)c1 +Cn1cc(CCNC(=O)Nc2ccc(-c3csnn3)cc2)cn1 +FC(F)(F)c1ccccc1NCc1ncccn1 +O=C(NCCc1cc(F)cc2c1OCOC2)NCc1ccccc1 +CCOc1ccc(CC2Oc3ccc(N)cc3N(CC)C2=O)cc1 +Cc1nn(C)c(N2CC(C(N)=O)CCC2C)c1N +Cn1nnnc1-c1cccc(C(=O)NCCn2cc(Cl)cn2)c1 +CN1CC(=O)N2CC(NC(=O)C3CCCO3)CC2C1=O +CCOC(=O)c1n[nH]c2cc(OC(F)F)ccc12 +CC(C)NC(=O)Cn1c(C(F)(F)F)nc2ccccc21 +CCOC(=O)c1cccc(N(CC)C(=O)c2cnc(C)cn2)c1 +Cc1cc(C)nc(SCc2nnnn2-c2ccc(F)cc2)n1 +CCc1cccc2c(C(=O)N3CCC(C(=O)NC(C)C)CC3)c[nH]c12 +CC(=O)N(C)CC(=O)Nc1ccc(-c2c[nH]cn2)cc1 +Cc1ccc2ncc(C(=O)N3CCCCC3c3cn[nH]c3)n2c1 +COc1ccc(C(=O)Nc2ccccc2C(=O)N2CCCC2)cc1C +CCNC(=O)c1ccc(CNC(=O)N2CCOC(C)(C)C2)cc1 +CC(C)(C)n1ncc2c(=O)[nH]c(N3CCN(CC(F)F)CC3)nc21 +CCc1cc(NCc2cc(C(N)=O)no2)nc(-c2ccccn2)n1 +COc1ccc(-n2ccnc2SCCN2CCOC2=O)cc1 +CCC(C)c1ccc(-c2csc(NC(=O)Cn3cnnn3)n2)cc1 +COc1ccc(-c2cn3cc(N)ccc3n2)cc1OC +COc1ccc(-c2nn(-c3ccc(F)cc3F)cc2CO)cc1 +C=CCNC(=O)C(C)Nc1cc(C#N)ccc1OC(C)C +O=C(CNS(=O)(=O)CCc1ccccc1)N1CCCC1 +Cc1c(Cl)cccc1NC(=O)CNC(=O)Cc1ccccc1 +Cc1cc(C)cc(OCC(=O)Nc2nc3c(s2)CNC3)c1 +O=C(Nc1ccc(F)cc1)NC(CCCO)c1ccccc1 +O=C(NCc1ccccn1)C1CCN(C(=O)c2cccs2)CC1 +O=C(NCc1nc(-c2ccccc2)cs1)c1nccc2ccccc12 +OCCCN1CCc2[nH]nc(-c3ccccc3F)c2C1 +CC(C)(C)OC(=O)C1CCCN1c1ccc2nccnc2n1 +CCc1nn(C)c(OC)c1CN(C)C(C(N)=O)c1cccc(F)c1 +CCCCn1nc(-c2ccc(OCC)cc2)cc(CO)c1=O +Cc1ccc(C(=O)N2CCN(C(=O)NC3CC3)CC2)cc1 +COc1cccc(-c2cccc(-c3ccn(CCCO)n3)c2)n1 +Cc1ccc(F)c(CNC(=O)c2cn(C3CCCCC3)nn2)c1F +COCCN1CCN(C(=O)c2cccc(-c3n[nH]c(C)n3)c2)CC1=O +COc1cc(OC)cc(C(=O)OCC(=O)N2CCCC2)c1 +CCCNC(=O)C(C)Nc1cc(C(C)C)ncn1 +C#CCNC(=O)c1ccc(-n2nc(C)c(Br)c2C)cc1 +CCOC(=O)C1CCCN(C(=O)c2ccc3ccccc3c2)C1 +CN(Cc1cccc(C#N)c1)C(=O)c1cnn(-c2ccc(F)cc2)n1 +CCCC(=O)Nc1ccc(NCC(=O)NC(C)(C)C)cc1 +CN1CCCC2(CCN(C(=O)c3cccn3C3CC3)C2)C1=O +CC(=O)c1ccc(NC(=O)C(C)c2c(C)noc2C)cc1C +CCc1nnc(CN(C)C(=O)c2cc3ccc(OC)cc3n2C)o1 +Cc1ccc(NC(=O)c2cccc(F)c2N)cc1C +CCNC(=O)c1ccc(NC(=O)c2ccc(C(=O)OC)cc2)cc1 +O=S(=O)(Nc1ccc(F)cc1)N1CCCCC1 +COc1ccc(CNC(=O)NCc2cccnc2OC)cc1 +Cc1cc(Cc2cc(C)c(O)c(CO)c2)cc(CO)c1O +COc1ccccc1CNc1nccc2c(N)ccc(F)c12 +CCc1nc(CC(=O)N2CCC(C(=O)N3CCCCC3)CC2)cs1 +CCOc1cccc(-c2cnn(C)c(=O)c2C(C)=O)c1 +Cc1cc(C)n(CCNC(=O)C2(c3ccc(F)cc3)CC2)c(=O)n1 +CC1C(=O)N(c2ccc(F)cc2)CCN1C(=O)c1ccco1 +COCCNC(=O)NC1CCCN(c2cc(N(C)C)ncn2)C1 +CCc1ccccc1OCC(=O)Nc1sccc1C(=O)OC +O=C(NCc1nnc2n1CCCCC2)c1ccc(-c2ccccc2)cc1 +Cc1ccc(OC(C)C(=O)NCCCN2CCOCC2)cc1 +O=C(CCCc1nc2ccccc2c(=O)[nH]1)Nc1cc(F)ccc1F +c1ncn(CCCc2nn3c(C4CCCC4)nnc3s2)n1 +Cc1cccc2c1cnn2CCC(=O)N1CC(C)OC(C)C1 +CCC(CC)N(CCO)C(=O)c1cccc(N)c1C +O=C(C1CCC1)N1CCN(Cc2ccccc2Cl)CC1 +O=C(NCCc1cccs1)C1CC(=O)N(c2ccccc2Cl)C1 +CC1CCN(C(=O)C(C)Sc2nnc(-c3ccccc3)n2C)CC1 +Cc1cc(-c2nnc(SCC(=O)Nc3ncccn3)o2)no1 +CCOc1ccccc1NC(=O)COC(=O)c1ccc2c(c1)OCO2 +CN(C)c1cccc(C(=O)NCCCn2cccn2)c1 +O=C(Nc1cc(F)cc(F)c1F)c1cc(Cl)ccn1 +COc1cc(C)c(C(=O)N2CCNC(=O)C2C(C)C)cc1OC +CCN(Cc1nc(-c2cccs2)no1)C(=O)c1ccccc1OC +Cc1cc2ccccc2n1CC(=O)Nc1nc2c(cc1C#N)CCCC2 +CC(C(=O)NCCNC(=O)CC1CCCCC1)c1ccsc1 +COc1cc2nc(-c3ccccc3)oc(=O)c2cc1OC +O=C(NCCc1ccc2c(c1)OCCO2)c1cccc(-n2cccc2)c1 +Cn1cc(OCc2ccccc2)c(=O)cc1C(=O)NCc1ccco1 +CCOc1ccc(OCC)c(NCc2cc(=O)n3ccccc3n2)c1 +COc1ccc(C2CC2C(=O)N2CCN(CCO)CC2)cc1 +CCCCNC(=O)CNc1ccccc1C(=O)N1CCCC(O)C1 +CCC(CO)N1CCN(C(=O)Cc2ccccc2O)CC1 +Cc1nc(COc2ccc(Br)cc2F)cs1 +COc1ccccc1CNC(=O)Cc1csc(-c2ccc(C)o2)n1 +Cc1nc(Nc2ccc3c(c2)OCCO3)c2c(C)noc2n1 +CCCCn1c(SC(C)c2nc(N)nc(N(C)C)n2)n[nH]c1=O +CC(=O)NCCc1ccc(C(=O)c2cc3nc(C)ccc3o2)s1 +Nc1c(-c2ccc(Cl)cc2)nnn1-c1ccc(F)cc1 +Cc1ccc(CC(=O)N2CCCc3cccc(C)c32)cn1 +O=C(NCCCO)c1nnc(-c2cccc(Cl)c2)o1 +COCCN(Cc1ccoc1)S(=O)(=O)c1ccccc1F +COc1ccc(C)cc1NC(=O)C1(C#N)CCCC1 +CNC(=O)c1cnc(-c2cc(OC)ccc2OC)nc1N +CCCCN(CC(F)(F)F)C(=O)c1ccc(N2CCNC2=O)cc1 +O=C(c1ccc2c(c1)CCCC2)N1CCCC1CO +COc1cccc(C(=O)NCc2nncn2C2CC2)c1F +Cc1cc(CN2CCN(C(=O)Nc3ccncc3)CC2)on1 +CC(C)NC(=O)c1cc(-c2ccn(-c3ccccc3)n2)n2ccccc12 +CC(C)(C#N)CCSc1nnc(Cc2cccc(F)c2)o1 +CCC1CCCN(C(=O)Cc2c(C)nc3nc(SC)nn3c2C)C1 +NC(=O)c1ccc(C(=O)N2CC=C(c3c[nH]c4ccccc34)CC2)cc1 +N#CCc1ccccc1C(=O)NCc1ccccc1 +O=C(C(c1ccc(F)cc1)C1CC1)N1CCOCC1 +CCOC(=O)N(C)c1ccc(NCc2cc(C#N)n(C)c2C)cc1 +CC(C)C(O)C1NCCc2cc(C(F)(F)F)c(O)cc21 +COc1ccc(CNc2nc(N3CCCC3)nc3c2cnn3C)cc1 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccccc1OC1CCC1 +CCOc1cc(OCC)c(C(C)O)cc1Br +CCOc1ccc(F)c(C(=O)Nc2cnc3c(c2)c(C)nn3C)c1F +COc1ccc(-c2cnc(NC(=O)NCC3CCCO3)n2C)cc1 +CCNc1ncc(C(=O)NCc2cnc(SC)n2C)cn1 +CNC(=O)c1ccc(NC(=O)c2ccc(-n3ccnc3)cc2)cc1 +O=C(Cc1ccc[nH]1)Nc1ccc(OC(F)F)c(F)c1 +Cc1ccccc1C1(CNC(=O)N(C)Cc2c(C)noc2C)CC1 +CC(C)(C)c1cc(=O)n2c(n1)SCC(C(=O)N1CCCCC1)C2 +O=C(c1ccco1)N1CCCN(C(=O)c2ccccc2Cl)CC1 +CCOCC(=O)N1CCN(CC(=O)NC2CC2)CC1 +CN1C(=O)C(C)(C)COc2c(N)cc(C(C)(C)C)cc21 +O=C(CCc1ccccc1O)NC1CCCNC1=O +NC(=O)C1CCC(CNC(=O)Nc2ccc3c(c2)COC3)CC1 +O=c1[nH]cnc2cc(Cl)c(Br)cc12 +CCCNC(=O)c1cccc(NCC(=O)N(C)c2ccccc2)c1 +CCc1nc2n(n1)CCCC2NC(=O)c1cc[nH]c1C +N#Cc1cccc(C(=O)Nc2ccnn2C2CCCC2)c1 +Cc1ccc(C(=O)N2CCN(c3cccc4[nH]ccc34)CC2)cc1 +O=C(CNC(=O)Nc1c(F)cccc1Oc1ccccc1)NC1CC1 +C=CCN(c1ccc(C(=O)Nc2cccnc2)cc1)S(C)(=O)=O +CC(C)(C)OC(=O)N1CCC(Nc2nc3ncccc3[nH]2)CC1 +CCC(NC(=O)N(C)CC)c1cc(F)ccc1F +Cn1cc(NC(=O)C(C)(C)C)cc(Br)c1=O +CC(=O)N1CCC(NC(=O)CCOc2cccc(F)c2)CC1 +O=C(CNC(=O)c1cc(F)cc(F)c1)NCCCn1cccn1 +CCOc1cc(C)c(-c2cc(C#N)c(N)[nH]2)cc1Cl +COc1cccc(COC(C)C(=O)NCc2cnc(C)s2)c1 +CC(C)OC(=O)CN1C(=O)CCOc2ccccc21 +Cc1ccc(C2COCCN2C(=O)c2cccc(N(C)C)c2)o1 +COc1ccc(C(=O)Nc2c(C)nn(C)c2C)c(F)c1 +O=C(NCCC(=O)N1CCCCC1)c1ccc2cnsc2c1 +Cc1nnc(CNC(=O)c2cc(-c3ccco3)on2)o1 +Cc1ccc(OCC(=O)Nc2ccc(Cl)cc2)nc1 +COc1ccc(OCCc2nc(C)c(C#N)s2)cc1 +CNC(=O)CC(C)N(C)Cc1nc2c(s1)CCCC2 +Cc1csc(N2CCCN(C(=O)NCc3cccc(F)c3)CC2)n1 +CC(C)(C)CC1CCCN1C(=O)c1scnc1C1CC1 +CNC(=O)COc1cccc(NC(=O)NCc2ncccc2C)c1 +CN(C)c1ccc(C(=O)NC(c2ccccc2)c2ccncc2)cn1 +CCCNc1nnc(-c2sc(N(C)C)nc2C2CC2)s1 +CC(C)Cn1c(NCCO)nc2c1c(=O)n(C)c(=O)n2C +Cc1cc(C)c(C(=O)NCC(C(C)C)N2CCOCC2)c(=O)[nH]1 +CC(=O)Nc1cccc(NC(=O)NCc2cc(Cl)ccn2)c1C +Cn1c(C(=O)NC2CCCCC2)nnc1-c1cccnc1 +Fc1ccc(C(F)(F)F)c2c1CCNC2c1ccccn1 +Cc1ccc(Cn2cc(NC(=O)c3ccncc3)cn2)cc1 +CC(=O)Nc1ccc(CNC(=O)CSc2nnc(N)[nH]2)cc1 +COc1cccc(C(CNCc2cscn2)N2CCCC2)c1 +Cc1sc2ncn(C(C)C(=O)OCc3ccccc3)c(=O)c2c1C +CC(C)NC(=O)Nc1cccc(C(=O)Nc2ccccc2O)c1 +CCOC(=O)C1CCCN(S(=O)(=O)N(C)C)C1 +Cc1ccc(F)c(-c2nc(CC(=O)NC3CCCC3)no2)c1 +O=C(NCCCN1CCOCC1)NCC1(c2ccccc2)CCCC1 +O=C(CN1C(=O)COc2ccc(Cl)cc21)NCc1ccccc1 +CCOC(=O)c1c(C)nc(SC)nc1C(F)(F)F +CCn1cc(NC(=O)Nc2nc(C)cs2)ccc1=O +O=C(Nc1ccc(O)cc1)c1ccc(-n2cnnn2)cc1 +N#Cc1ccc(OC(=O)c2cccc(-n3cccn3)n2)c(Cl)c1 +COc1c(CNC(=O)NCCc2ccncc2C)c(C)nn1C +CCS(=O)(=O)N1CCC(C(=O)OC(C)C)CC1 +Cn1cnnc1S(=O)(=O)Cc1ccc(F)c(Br)c1 +COCCOc1ccccc1NC(=O)c1cnn(C(C)(C)C)c1 +CC(C)CC(C)OCC(=O)Nc1ccc(Cl)c(N)c1 +COc1cccc(C(=O)Nc2cnn(-c3ncccn3)c2)c1 +CCc1noc(CN(C)C(=O)Nc2cc(-c3ncco3)ccc2C)n1 +Cc1ccc(N2CCC3C(COC3Cc3n[nH]c(C)n3)C2)nn1 +CCC(NC1CCCCNC1=O)c1ccc(O)cc1 +O=C(NC1CCN(C(=O)Nc2cccnc2)CC1)C1CCCCC1 +Cc1n[nH]cc1NC(=O)CNC(=O)c1ccccc1F +CC(C)(NS(C)(=O)=O)C(=O)Nc1ccc2c(c1)COC2 +O=C(CNC(=O)c1ccccc1)Nc1ccc(N2CCCCC2)nc1 +N#CCc1cc2c(n(CC3CCCO3)c1=O)CCC2 +Cc1ccc(NC(=O)c2cnc3ccccc3n2)cc1F +CCC1c2cccn2CCN1C(=O)c1noc2c1CCCC2 +CCc1nnc(NC(=O)CNS(=O)(=O)c2ccc(C)cc2)s1 +Cc1cc(CN2CCN(C(=O)NCCc3cccnc3)CC2)on1 +Cc1noc(C)c1CN1CCOC2CN(C(=O)c3ccoc3)CC21 +Cc1onc(-c2ccc(F)cc2)c1C(=O)N1CCn2c(C)nnc2C1 +CC(=O)Nc1cccc(C(=O)NC(C)c2ccccc2C)c1 +COc1ccc(OC)c(-c2cc(=O)c3cc(F)ccc3o2)c1 +CC(C)c1nc2cc(Br)cnc2n1CCCO +CCCC1CN(C(=O)CN(C)C(=O)c2ccccc2)CCO1 +COc1cc(F)cc(CNC(=O)Nc2ccn(CC(F)F)n2)c1 +COc1cccc(C)c1NC(=O)NC(C)c1nncn1C(C)C +CC(=O)NC(C)(C)c1noc(-c2cc3ccc(C)cc3[nH]2)n1 +CCCNC(=O)c1ccccc1NC(=O)c1ccc(NC(C)=O)cc1 +CCC(C(=O)Nc1cccc(CO)c1)c1ccccc1 +COc1cccc2sc(NC(=O)Cc3ccsc3)nc12 +COC(=O)NCc1ccc(NC(=O)C(C)Cc2ccccc2F)cc1 +Cc1ccc(NC(=O)NCCS(=O)(=O)NCC2CCC2)cc1C +Cc1ccccc1OS(=O)(=O)c1cccc2cccnc12 +CC(C)CCOCCN1CCc2ccc(S(N)(=O)=O)cc21 +O=C(c1ccc2[nH]ccc2c1)N1CC2CC(C1)c1cccc(=O)n1C2 +O=C(Nc1ccccc1N1CCOC1=O)c1ccc(-n2ccnn2)cc1 +CCc1ncc(CN2CCOC(Cc3cccc(F)c3)C2)cn1 +COC(=O)C(NCc1ccccc1F)C1CCCC1 +CC(C)C1Nc2ccccc2N(CCCC#N)C1=O +Cc1cnc(NC(=O)C2CN(c3nc4ccccc4s3)C2)s1 +COC(=O)CN1CN=C2C(=Nc3cc(OC)c(OC)cc32)C1=O +Cc1nc2ccccc2n1Cc1nnc2sc(-c3cccnc3)nn12 +COc1cccc(C(=O)OC(C)c2nc(C)no2)c1OC(F)F +CC(C)CN(CC(C)C)C(=O)Nc1ccc(CN2CCCC2=O)cc1 +C=CCN(CC=C)C(=O)C(C)NC(=O)c1ccc(C)s1 +CCCCC(=O)Nc1cc(OC)c(OC)cc1Br +COc1cccc(C(N)=O)c1OCC(=O)N1CCOC(C)C1 +Nc1cc(C(O)CNc2cccc(F)c2)ccc1Cl +CSc1cccc(NC(=O)COc2ccccc2F)c1 +O=C(Cn1cnnn1)NC1(c2ccc(Br)cc2)CC1 +CCn1nc(C(C)C)cc(C(N)c2ccc(Cl)cc2)c1=O +NC(=O)C1CCCN(C(=O)CNc2cccc3c2OCCO3)C1 +O=C(NCCCN1CCOCC1)c1cccc2cccnc12 +CC(C)c1csc(NC(=O)COc2ccc3ccc(=O)oc3c2)n1 +CC(=O)c1c(C)[nH]c(C(=O)NCCCN(C)S(C)(=O)=O)c1C +Cc1cccc(NC(=O)c2onc(-c3ccccn3)c2N)c1C +CNC(=O)C1(S(=O)(=O)c2ccc(C)cc2)CCC1 +COc1cc(-c2noc(CN(C)C(=O)c3cccs3)n2)ccn1 +O=C(NCc1ccccc1Cn1cccn1)C1(c2ccccc2)CC1 +CC(c1cccnc1)N(C)Cc1ccc(C(=O)N(C)C)[nH]1 +OC(Cn1cnc2cc(F)c(F)cc21)c1ccc(F)cc1 +Cc1[nH]c(=O)c(S(=O)(=O)c2ccccc2)c(C)c1Cl +O=C(c1ccccn1)N1CCCC(c2[nH]ncc2Cc2ccccc2)C1 +CC(C)Oc1ccc2c(C(=O)NCC(N)=O)cc(=O)oc2c1 +CCOC(=O)C(C)(C)n1nc(C#N)cc1-c1cccs1 +CNC(=O)c1c(-c2cccc(Cl)c2)noc1C +COc1cc(F)c(C(C)NC(=O)c2cccnc2)cc1OC +Cc1ccc(S(=O)Cc2ncc(Cl)cc2Cl)nc1 +Cc1sc2ccccc2c1CC(=O)N1CCN(C)CC1 +CCCN(Cc1nnc(-c2ccco2)o1)C(=O)c1cc(Cl)cn1C +CCC(=O)N1CC2CCC(C1)N2CC=Cc1ccccc1 +CCn1nnnc1-c1ccc(OC)c(S(=O)(=O)NC)c1 +CC(Cc1ccccc1Br)NC(=O)c1ccon1 +CCCCC(NC1=NS(=O)(=O)c2ccccc21)C(=O)NC +O=S(=O)(CCCOn1nnc2ccccc21)c1ccc(F)cc1 +COc1ncccc1CNC(=O)N1C(C)CCCC1C +Cc1cc(OC(C)C(=O)NCc2ccncc2)cc(C)c1Cl +CN1CCC(=O)Nc2cc(C(=O)N3CCOCC3C3CC3)ccc21 +CCS(=O)(=O)N1CCc2cc(OC)c(OC)cc2C1 +O=C(NCC1(CO)CC1)c1ccc(-n2cncn2)c(F)c1 +COc1cccc(C(=O)N2CCC(Oc3cnccn3)CC2)c1 +Cc1nc(C)c(CNC(=O)Nc2cnn(-c3ccccc3F)c2)s1 +NC(=O)Cc1ccc(OCC(=O)N2CCCCc3ccccc32)cc1 +Cc1cc(C)cc(CN2CCN(c3nc(C)cs3)CC2)c1 +CC(C)(C)OC(=O)Nc1cc(Br)ccc1O +COC1CCCC(OC(=O)C2CC(=O)N(Cc3ccco3)C2)C1 +CNC(=O)CN(C)C(=O)CCCc1nc(C(C)(C)C)no1 +CCOc1cccc2c1OCC(=O)N(c1cc(F)cc(F)c1)C2 +CC(C)Cc1ncc2c(n1)CN(C(=O)C1CCCO1)C2 +FC(F)(F)c1ccccc1Cn1ccnc1C1CC1 +Cc1cc(C(=O)NCc2cnn(Cc3ccccc3)c2)no1 +COc1ccc(CCOc2ccc(N(C)C(N)=O)cc2)cc1 +O=C(COc1cccc(Cl)c1)NC1CCCC1 +CN(C)C(=O)c1ccc(CNC(=O)C2CC=CC2)cc1 +Cc1ccnc(SCCCNC(=O)Nc2cc(C)on2)n1 +CN(C)C(=O)Cn1ccc2cc(NC(=O)C3CCOC3)ccc21 +Cc1cccc(OCC(=O)Nc2ccc(C)c3cn[nH]c23)c1 +C#CCn1c(-c2ccc(N)cc2)nc2cc(OCC)ccc21 +CCc1cnc(CN(C)C(=O)NCCc2cccc(O)c2)s1 +O=C(OCC(=O)N1CCOCC1)c1ccccc1Cc1ccccc1 +C=CCOCC1CCCC12CN(Cc1ccncc1)CCO2 +COc1cccc(OCC(=O)Nc2ncccc2CO)c1 +Cn1c(N)nnc1SCCOc1ccc(C#N)cc1 +CCS(=O)(=O)N1CCC(C(=O)Nc2ccc3[nH]ncc3c2)CC1 +CCC1CCCN(C(=O)NCc2cnc(C)s2)C1 +CC(NC(=O)CN1CCCSc2ccccc21)c1ccco1 +CCn1cc(C(=O)Nc2cc(C(=O)N3CCCC3)ccc2OC)cn1 +c1ccc(-n2cc(CNc3ccc(-n4cncn4)cc3)cn2)cc1 +CC(C)c1ccc(C2CCCN2C(=O)CNS(C)(=O)=O)cc1 +CCC(C)NC(=O)CN(c1ccc(C)cc1)S(=O)(=O)N(C)C +CCCCN(CCO)C(=O)NC1CCSc2ccc(Cl)cc21 +CC(=O)N(C)CC(=O)NCC(C)(C)c1ccncc1 +CCn1nnnc1SCc1c(C)cc(C)c(C(C)=O)c1C +CCCc1n[nH]c(C2CN(CCn3cncn3)CCO2)n1 +Nc1ccc2c(c1)sc1nc(-c3ccccn3)cn12 +CC(C)CNc1ccc(S(=O)(=O)N2CCOCC2)cc1 +O=C(CC(F)(F)F)N1CCN(CC(O)c2ccccc2)CC1 +CCCOc1ccccc1NC(=O)Cn1ccccc1=O +CC(=O)Oc1ccccc1-n1c(C)nc(=O)c(-c2ccccc2)c1C +O=C1CC2(CCCCN2C(=O)C2CCCCC2)CN1CC1CC1 +c1cnc(-c2cnc(NC3CC3)nc2C2CC2)cn1 +Cc1noc(C2CCCN(Cc3cc(Cl)c4c(c3)OCO4)C2)n1 +O=C(Cn1cc(Cl)cn1)N1CCCC(Cc2ccccn2)C1 +O=C1CN(C(=O)Cn2nnc(-c3ccsc3)n2)c2ccccc2N1 +CNS(=O)(=O)c1ccc(CNC(=O)c2c(C)oc(C)c2C)cc1 +Cc1ccc(CNC(=O)NC(C)COCC(F)(F)F)s1 +CC(C)(C)NC(=O)c1cnc(N2CCCCC2)nc1N +O=C(CSc1ccc(F)c(F)c1)Nn1cnc2ccccc2c1=O +COc1cc(C)c(S(=O)(=O)N(C)CC(N)=O)cc1OC +CN(Cc1ccccc1)C(=O)c1ccc(OCC2CCCO2)cc1 +CC(=O)NCc1ccc(-c2nc(CC(C)C)no2)cc1 +CC1CCN(C(=O)CSc2nc(-c3ccccc3)cc(=O)[nH]2)CC1 +CCN(c1ccccc1)S(=O)(=O)c1cc(-c2nnc(C)o2)cs1 +COC(C)(C)c1noc(CCn2nc3ccccn3c2=O)n1 +O=C(Nc1ccc2[nH]c(-c3ccc4nc[nH]c4c3)nc2c1)c1ccco1 +Cc1noc(C2CCCN(Cc3ccccc3Br)C2)n1 +COc1ccc(CC(=O)Oc2cccc(C)c2)cc1OC +CCOc1ccc2nc(SCc3cc(C)on3)[nH]c2c1 +CC(=O)N1CCC(c2nc(C)cc(Nc3ccccn3)n2)C1 +CN(CCOCC1CC1)C(=O)c1cc(C(N)=O)c[nH]1 +O=C(CCc1csc2ccccc12)NCC(=O)Nc1cccnc1 +O=C1CC2(CCN(C(=O)c3ccncc3F)CC2)CN1 +COc1cc2c(cn1)N(C(=O)OC(C)(C)C)CC2 +CS(=O)c1nncn1CC(=O)NCCC1=CCCCC1 +O=C(Nc1ccccc1)C1CCN(C(=O)COc2ccccn2)CC1 +COCCCCCNC(=O)Nc1cc(C)ccc1C +Cc1ccccc1Cn1nc(C(C)C)nc1CCCC(N)=O +Cc1cc(F)ccc1S(=O)(=O)N(CCO)C(C)(C)C +Cc1ccc2c(c1)C(NC(=O)c1ccc(O)cc1)CNC2 +CCN(Cc1ccccc1)C(=O)c1ccc2ncnn2c1 +NC(=O)N1CCCN(C(=O)c2ccc3c(c2)Cc2ccccc2-3)CC1 +CCOC(=O)CCC(=O)Nc1ccc(-c2cc[nH]n2)cc1 +C#CCCCOC(=O)C1CC(=O)N(c2ccc(OC)cc2)C1 +Cc1ccc(NC(=O)CCn2c(=O)oc3ccccc32)cc1Cl +CN(Cc1cccc2ncccc12)C(=O)c1cnc(C2CC2)[nH]c1=O +O=C(Nc1ccc(Oc2nncc3ccccc23)cc1)c1ccon1 +CC(=O)Nc1ccc(C(=O)c2cc3cc4c(cc3o2)OCO4)c(F)c1 +CCN1CCOC(C(=O)Nc2cc(OC)ccc2F)C1 +Cc1n[nH]c(-c2cccc(CNC(=O)C3CC=CC3)c2)n1 +COCCN(Cc1ccccc1)C(=O)Nc1c(C)cccc1C +NC(=O)c1cccc(CNC(=O)NCCC2=CCCCC2)c1 +O=C(NC1CCCC1)c1nnn(-c2ccccc2)c1C1CC1 +NC(=O)C1CCN(C(=O)CCC2Cc3ccccc3NC2=O)CC1 +CN(C(=O)CSc1nccn1C)C1CCCCC1 +CC1CCN(C(=O)COC(=O)C23CC4CC(CC(O)(C4)C2)C3)CC1 +CCOC(=O)C1=C(C)NC(=O)CC1c1ccc(Cl)cc1 +O=C(NCc1n[nH]c(=O)[nH]1)C1COc2ccccc2C1 +CCc1nc(COC(=O)c2cc(F)ccc2C)cs1 +CCOC(=O)CCC1(C(F)(F)F)Nc2ccccc2N1 +CN1CCN(C(=O)c2cccc(N(C)C)c2)C(c2ccccc2)C1 +CCOC(=O)c1nnc2c(-c3ccc(OC)cc3)c(CC)nn2c1N +COCCC(=O)NC(C)C12CC3CC(CC(C3)C1)C2 +CCc1ccc(N2CC(C(=O)Nc3ncc(C)s3)CC2=O)cc1 +CCn1cc(NS(=O)(=O)c2cnn(C)c2C)c(C(=O)NC)n1 +Cc1ccc(C)c(NC(=O)N2CCC(N3CCOC(C)C3)CC2)c1 +CCC(C)C(=O)NCCc1ccc(-n2cccn2)cc1 +O=C(NCCc1ccco1)c1ccc(F)cc1Br +O=C(CCn1c(=O)oc2ccccc21)Nc1ccccc1F +O=C1CCC(NC(=O)C23CC4CC(CC(C4)C2)C3)CN1 +CSc1ncc(Cl)c(C(=O)Nc2nccs2)n1 +CC(=O)c1cc(C(=O)Nc2cccc(C)c2)c(=O)[nH]c1C +COc1c(C)c2c(c(O)c1Br)C(=O)OC2 +Cc1ccc(NC(=O)Cn2nc(C)c(Cl)c2C)c(Cl)c1 +CCCNC(=O)Nc1cc(C#N)ccc1OC(C)C +CCN(CC)C(=O)C1(C)CC1(Br)Br +CCc1onc(C)c1NC(=O)CC1(C)CCCCC1 +CSc1ccc(OC(=O)c2cccc(-n3cnnn3)c2)cc1 +Nc1nc(COC(=O)Cc2noc3ccccc23)nc2ccccc12 +O=C(CCc1cccc(F)c1)Nc1cccc(-c2nc[nH]n2)c1 +CCc1cnn2c(=O)c(-c3ccccc3)c(C)[nH]c12 +Cc1c(C(=O)NCC(C)(O)c2cnn(C)c2)nnn1-c1ccccc1 +COc1c(C(=O)NCC2CCCO2)nnn1Cc1ccccc1 +CCNC(=O)CCc1nc2sc3c(c2c(=O)[nH]1)CCC3 +CC(C)(C)OC(=O)N1CCC(Nc2cncnc2)CC1 +Cn1cc(CC(C#N)C(=O)Nc2cccc(O)c2)c2ccccc21 +CCCCCCN1C(=O)C(C)C(=O)c2ccc(N)cc21 +CC1(C)Cc2cccc(OCCNC(=O)c3cc(Cl)c[nH]3)c2O1 +CC(NC(=O)Cn1cc(Br)c(=O)[nH]c1=O)C1CCCO1 +COc1ccc(Cl)c(NC(=O)N2CCC(C)CC2)c1 +O=C(c1ccc(=O)n(Cc2ccc(F)cc2)n1)N1CCCCC1 +CC(=O)Nc1cccc(C(=O)Nc2ccc(-n3cncn3)c(F)c2)c1 +O=C(CCC1Cc2ccccc2NC1=O)Nc1ccc(Cl)cn1 +CN1CC(C(=O)N2CCOC(c3ccc(Cl)cc3)C2)CC1=O +CCC(=O)N(CC=Cc1ccccc1)c1ccc2c(c1)OCCO2 +CCN(CC)C(=O)CN(C)C(=O)CCNC(N)=O +O=C(COc1ccccc1O)NC1c2ccccc2Oc2ccccc21 +CC(=O)N1CCC(c2nccnc2-c2cnn(C)c2)CC1 +CCC1CN(C(C)=O)CCC1NC1CCCN(c2ccccc2)C1=O +CCC(C)N(C)C(=O)Nc1cccc(OCCn2cccn2)c1 +CC1CN(C(=O)c2ccc(COc3ccc(Cl)cc3)cc2)CCO1 +Cc1cc(NC(=O)CCCOc2ccccc2)n(-c2ccccc2)n1 +COCCN(Cc1ccc(OC)cc1)C(=O)Nc1ccccc1 +O=C(Cc1ccccn1)N1CCc2nc(N3CCCC3)[nH]c(=O)c2C1 +Cc1cccc(C(=O)NCC(=O)Nc2cccc(-n3cnnc3)c2)c1 +CCOC(C)c1noc(CN(C)C(=O)c2ccncc2)n1 +Cc1cc(CNC(=O)c2cccc(NC(=O)C3CC3)c2)c(C)o1 +Cc1cccc(NC(=O)c2cc(C(F)(F)F)n(C)n2)c1C +CN(CCCOc1ccccc1)C(=O)C1CNC(=O)N1 +Cn1cc(C(=O)N2CCC(c3ccc4c(c3)OCO4)C(O)C2)cn1 +CCc1nc(NCCCN2CCOCC2)c2oc3ccccc3c2n1 +O=C1NCC2CN(Cc3cccn3Cc3cccs3)CCN12 +Cc1nc(CNC(=O)Nc2cccc(-c3cn[nH]c3)c2)no1 +O=C(NCc1ccccc1N1CCCC1)Nc1ccccc1F +COc1ccc2c(CN3CC(C)OCC3C)cc(=O)oc2c1 +CCOCCC(=O)Nc1c(-c2ccccc2)nc2ccccn12 +CN(Cc1ccc(F)c(F)c1)C(=O)c1sccc1-n1cnnn1 +CCN(CC)C(=O)CN(C)C(=O)c1cnc(-c2cnn(C)c2)s1 +Cc1ccncc1N1CCN(c2ccc3scnc3c2)C1=O +CC(=O)N1CC2(CCN(C(=O)C(C)C)CC2)C2(CCN(C)C2=O)C1 +COC(=O)CCC(=O)c1ccc(Cl)c(Cl)c1 +CC(C)N1CC(C(=O)N2CCN(Cc3ccncc3)CC2)CC1=O +COc1ccc(CNC(=O)c2ccccc2F)c(OC)c1 +CCN(Cc1nc(COC)no1)C(=O)c1ccccc1C +CCOC(=O)C1C(c2cccnc2)NC(=O)NC1(O)C(F)(F)F +O=C(CCC1CCCC1)NCC(=O)Nc1ccc(F)cc1 +CCCc1cc(C(=O)NC(COC)C(N)=O)[nH]n1 +COC(=O)c1noc(C(=O)Nc2ccc3c(c2)OCO3)c1N +CC(NC(=O)N(C)CCOCC1CC1)c1ccncc1 +N#Cc1ccccc1NC(=O)COC(=O)c1cccnc1 +CCC(CC)NC(=O)CNC(=O)c1ccc2c(c1)OCO2 +Cc1nc(N)c(C#N)c(-c2ccc3c(c2)OCO3)c1C +Cc1noc(C)c1COc1ccccc1C(=O)NCC1CC1 +O=C(c1cnccn1)N1CCC(Nc2ccc(Cl)cn2)CC1 +COc1cccc(-c2noc(CCNC(=O)c3ccccc3)n2)c1 +Cc1nc2ccc(NC(=O)c3cn(Cc4ccccc4)nn3)cc2o1 +CC(=O)Nc1cc(C(=O)NC(C)(C)C)nn1-c1ccccc1 +CC(C)C(=O)N1CCC(C(=O)NC2(C#N)CCCCC2)CC1 +CC(C)NC(=O)C1=NC=C(S(=O)(=O)N2CCOCC2)C1 +CCN(CC)C(=O)c1coc(NC(=O)c2cccs2)n1 +CCN(CC)C(=O)C1CC=CCC1C(=O)Nc1ccc(O)cc1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1cccs1 +O=C(OCCNc1cccnn1)C1(c2ccccc2F)CC1 +CC(=O)Nc1ccc2c(c1)C(c1ccnnc1)NCC2 +Cc1cc(N2CCN(Cc3ccc(F)c(F)c3)CC2)nc(C(C)C)n1 +CCOc1ccc(C(=O)Nc2cc(OC)ccc2OC)nn1 +CCOC(=O)CN(CC)C(=O)Cc1ccccn1 +CC(=O)c1cccc(S(=O)(=O)N(C)Cc2ccco2)c1 +Cc1noc(C(NC(=O)Cc2ccc(Cl)cc2)c2ccccc2)n1 +CCN(CC)S(=O)(=O)c1ccc(Sc2nnc(C)s2)nc1 +Cn1ncc2c(N3CCOCC3)nc(Nc3ccccc3)nc21 +Cc1ccccc1C(C#N)NCCN1CCOCC1 +Cc1nn(C)c(C)c1CC(=O)Nc1ccc(=O)n(C)c1 +Cc1ccc(CN(C)C(=O)c2ccc3c(c2)NC(=O)CO3)s1 +CC(C)NC(=O)C1CCC(CNC(=O)c2cnn3ncccc23)CC1 +CCC(=O)Nc1ccc(C)c(NCC(=O)N(CC)CC)c1 +Cc1cc(C(=O)N2CCC(Nc3cccnn3)CC2)n(C)n1 +CSc1ccc(OC(C)C(=O)Nc2ccc(NC(C)=O)cc2)cc1 +O=c1[nH]c2ccccc2c(=O)n1CCCN1CCOCC1 +COCC(C)CNC(=O)c1ccccc1NC(C)C +CN(C)CC(Cc1ccccc1)NCc1ccco1 +Cc1cccc2c(=O)n(CC(=O)Nc3cccc(O)c3)cnc12 +Cc1ncsc1CNC(=O)c1ccc(F)cc1Br +COc1ccc2c(c1)OCC(C(=O)N(Cc1ccncc1)C1CC1)C2 +COCCCNC(=O)c1nn(CC(C)C)c(=O)c2ccccc12 +CC(=O)Nc1ccc(F)c(NC(=O)COCc2nc(C)no2)c1 +Cn1c2ccccc2n2c(=O)c(C#N)c(-c3ccccc3)c(C#N)c12 +O=C(Nc1ncccn1)c1cc(OCc2ccccc2)no1 +Cc1nc(C(=O)Oc2ccc3c(c2)ncn3C)cs1 +COCC(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 +Cc1cc2nc(SCC#N)n(-c3ccc(F)cc3)c(=O)c2[nH]1 +O=C(c1ccoc1)N1CCN(C(=O)c2ccsc2)CC1 +CNC(=O)CCNC(=O)NC(c1c(F)cccc1F)C(F)(F)F +O=c1ccc(C2NCCc3c(F)cc(F)cc32)c[nH]1 +Cc1ccc2ncc(C(=O)N3CCN(C)c4ccccc43)n2c1 +CCc1nnc(CNc2nc3c(s2)c(C)nn3C)s1 +c1ccc(-n2cccn2)c(CN2CCOC3(CCc4ccccc43)C2)c1 +Cc1cnc(N)nc1N1CCC(CCn2cccn2)CC1 +COc1ccc(NC(=O)Nc2cc(OC)ccc2F)cc1 +O=C(COC(=O)c1ccc(F)cc1F)c1ccccc1 +Cc1c(C(=O)N2CCCCCC2)oc2c1C(=O)CCC2 +CC(=O)Nc1nc(C(=O)NCc2ccnc(OC3CCC3)c2)cs1 +COc1ccc(OCCSc2nncn2C)cc1 +COc1ccc(C)cc1C(=O)N(Cc1ccccn1)C1CC1 +c1ccc(Cn2ncc3c(NCc4ccco4)ncnc32)cc1 +Cc1ccnn1CCC(=O)NC1(c2ccccc2F)CCCC1 +COC(=O)CCNC(=O)Cc1c[nH]c2ccccc12 +C=CCNC(=O)N(CCc1ccccc1)Cc1cccnc1 +CC1(C)C(NC(=O)Cc2coc(-c3ccccc3)n2)C2CCOC21 +COc1ccc(C(=O)N(Cc2ccc(OC)cc2OC)C2CC2)cc1 +Cc1ccc(Sc2ncccc2C(=O)N2CCC(O)CC2)cc1C +O=C(NCCCNc1ncccn1)c1ccc(O)c(Cl)c1 +N#Cc1ccc(NC(=O)CCn2ccccc2=O)cc1 +COC(=O)N1CCC(NC(=O)c2cc(F)c(Cl)cc2Cl)CC1 +CC(C)C(C)(CNC(=O)OC(C)(C)C)NC(=O)c1ccc(F)nc1 +N#Cc1cccnc1NCc1cccnc1Oc1ccc(F)cc1F +O=C(Nc1cc(Cl)ccc1F)c1ccc(-n2cccn2)cc1 +COc1ccc(-c2nn3c(C)cc(C)nc3c2C)cc1OC +CCNC(=O)c1sc2ncnc(NC(CC)COC)c2c1C +COC(=O)c1ccc(NC(=O)CCNC(=O)c2ccco2)s1 +CC1CCN(C(=O)c2cnn(-c3ccccc3)n2)CC1 +COc1ccccc1CN(C(=O)c1ccnc(-n2ccnc2)c1)C1CC1 +O=C(NCCc1ccc(O)cc1)c1ccc(Cn2cc(Cl)cn2)o1 +CCCN(c1nc2c(s1)c(C)nn2C)C1CCCCC1O +Cc1ccc(C(C)NC(=O)CSc2nncs2)cc1F +CC(NC(=O)Nc1nnc(C2CC2)s1)c1ccc(F)c(Cl)c1 +CC(C)NC(=O)CCNC(=O)c1nc2c(F)cccc2s1 +CCN(CC(=O)N(CC(C)C)C1CC1)c1ccccc1 +CC1CCN(C(=O)NCC(=O)N2CCCC2)C(C)C1 +COCCNC(=O)c1nc(Cn2c(C)nc3ccccc3c2=O)no1 +COCCN1C(=O)C2CCC1CN(C(=O)c1cc3sccc3[nH]1)C2 +NC(=O)CCCNC(=O)COc1cc(Cl)ccc1Cl +CC(=O)N1CCc2ccc(NC(=O)c3ccc(F)cc3Cl)cc21 +Cc1ccc(-c2cc(C(=O)Nc3cnc4c(c3)c(C)nn4C)on2)cc1 +O=C(Cc1ccccc1)OCn1nnc2ccccc2c1=O +COc1ccc(NC(=O)c2cccc(-n3cnnc3)n2)c(OC)c1 +CCN(Cc1noc(C2CC2)n1)C(=O)c1ccc(F)cc1F +COC(=O)COc1cccc(NC(=O)c2ccco2)c1 +Cc1cc(NCCN(C)S(C)(=O)=O)nc(-c2cccnc2)n1 +CC(c1nc(-c2cccnn2)no1)n1cc(Cl)cn1 +CCNC(=O)CCSc1nnc(-c2ccccc2C)o1 +Cc1nc(S(=O)(=O)N(C)c2ccccc2-c2ccccc2)cn1C +CC(=O)N1CCC(C(=O)N2CCN(c3ccc(C#N)cn3)CC2)CC1 +CCOc1ccc2cc(C(=O)Nc3cc(C)on3)[nH]c2c1 +COc1ncccc1CNC(=O)N1CCN(c2cnccn2)CC1 +CN(CCC#N)S(=O)(=O)N1CCCN(S(C)(=O)=O)CC1 +Nc1ccc(C(=O)Nc2ccc(Br)cc2)cn1 +COc1cc(CCNC(=O)N2CCc3cc(F)ccc3C2)ccc1O +CC1CC(C)CN(C(=O)C2CN(C(=O)c3ccc(F)c(F)c3)C2)C1 +O=C(Cn1cnc2cnccc2c1=O)N1CCCc2ccccc21 +CCCNC(=O)CCNC(=O)c1cnn(C)c1-n1c(C)ccc1C +Cc1ccc(F)c(NC(=O)CSc2ncc(C#N)c(N)n2)c1 +CC(C)NC(=O)C1CC(=O)N(c2n[nH]c3ccccc23)C1 +Cc1nc(NC(=O)N2CCCC(F)(F)C2)nn1C +Cc1ccn(-c2ccccc2NCC2CCOCC2)n1 +CC(=O)N1CCCn2nc(CNc3cc(C)ncn3)cc2C1 +COc1cc(C(N)C(=O)NCCCO)ccc1O +N#Cc1cc(-c2ccccc2)cnc1NCc1cccnc1 +O=C(Nc1ccc2nccn2c1)c1ccn(-c2ccc(F)cc2)n1 +O=C(c1ccc(F)cc1)N1CCn2c1nc1ccccc1c2=O +CNC(=O)c1cccc(CCNC(=O)c2ccc(-n3ccnn3)cc2)c1 +Cc1cccc(C(=O)NCCCn2cnc3ccccc32)c1 +CS(=O)(=O)c1ccc2c(c1)N(C(=O)Cc1ccc(F)cc1)CCC2 +CCNS(=O)(=O)c1ccc(C(=O)NCCC(C)C)cc1 +CCn1c(SCC(=O)OC(C)C)nnc1-c1cccs1 +CC(c1ccc(F)cc1)N(C)C(=O)c1cc(C(N)=O)cs1 +O=C(NCC(O)c1ccco1)C1CC(=O)N(CCc2ccccc2)C1 +CCNC(=O)c1ccc(NC(=O)COCC2CC2)c(C)c1 +CCSc1nc2n(n1)C(c1ccc(C)o1)C(C(N)=O)=C(C)N2 +Cc1ccc(Cn2nnc3cc(C(=O)N4CCC(C)CC4)ccc32)cc1 +Cc1nc(C)c(Cc2nc(Cc3ccc(Cl)cc3)no2)c(=O)[nH]1 +CCn1cc(CNC(=O)Nc2cccc(C(C)=O)c2)cn1 +CCNC(=O)CNC(=O)NC(c1ccccc1OC)C(C)(C)C +COc1nn(C)cc1C(=O)Nc1nnc(-c2ccco2)o1 +NS(=O)(=O)c1cc2c(cc1Br)NC=NS2(=O)=O +COc1cccc(C(=O)N(C)C2CCCC(C)C2)c1F +Cc1csc(=O)n1CCSc1nnc2ccccn12 +COc1ccc(N2CCN(C(=O)c3cc(C(C)C)on3)CC2=O)cc1 +COCCN(CC(C)C)S(=O)(=O)c1ccc(F)c(C#N)c1 +CCc1c(C(=O)OC)ncc2[nH]c3cc(OC)c(OC)cc3c12 +CN(Cc1cccc(C#N)c1)C(=O)Nc1cccnc1 +COc1ccccc1-c1nc(-c2ccc3c(c2)nc(C)c(=O)n3C)no1 +Cc1ccc(C)c(C(=O)N2CCN(C(=O)CCC(C)C)CC2)c1 +O=C(CN1CCc2ccc(Cl)cc2C1)NCCCN1CCCC1=O +O=S(=O)(N1CCCCCC1)N1CCCC1c1ccc[nH]1 +Cc1ccc(NC(=O)NCC(O)CN2CCCC2=O)cc1 +NC(=O)CC1CCN(C(=O)Nc2ccncc2)CC1 +CCCOC(=O)CN1CC(C)Oc2ccc(C(C)=O)cc21 +Cc1noc(C)c1N(C)C(=O)c1cc(Br)c(C)[nH]c1=O +N#Cc1ccc(S(=O)(=O)NCc2cc(Cl)ccn2)cc1 +CC(C)CC(NC(=O)c1cc(C(C)C)nn1C)c1ncnn1C +O=C(NCc1ccccc1Cl)c1cc(F)ccc1F +Cc1cc(C(O)CCNC(=O)NCc2ccc(F)cc2)c(C)o1 +CCC(C)Nc1ncnc(Nc2nc(C)c(C)s2)c1N +Cc1cc(C)cc(NC(=O)c2cc(-c3cccnc3)[nH]n2)c1 +Cn1ncc(Cl)c1C1CCCCCN1S(=O)(=O)N1CCCC1 +COc1cccc(OC2CN(C(=O)c3ccn(C(C)(C)C)c3)C2)c1 +Cc1ccc(Cn2c(CO)nc3cc(C)ccc32)cc1 +COc1ccccc1-c1nc2cnccn2c1NCc1ccco1 +Cn1cc(C(N)=O)cc1C(=O)OCC1CCCO1 +CC(NS(=O)(=O)c1cccc(C#N)c1)c1ccc2c(c1)OCCO2 +O=C(CSc1ccccn1)NCC(F)(F)F +Cc1ccc(C)c(OC2CCN(C(=O)Nc3cc(C)on3)CC2)c1 +COC(=O)Cn1cc(NC(=O)Cc2ccccn2)cn1 +O=C(CCNc1ncnc2[nH]cnc12)NCc1ccccc1 +CC1(C)Cc2cccc(OCC(=O)Nc3ccccn3)c2O1 +Cc1ccc(O)c(-c2n[nH]c3c2C(c2ccc(F)cc2)N(C)C3=O)c1 +Cc1cccn2cc(C(=O)NCC(=O)Nc3nccs3)nc12 +NS(=O)(=O)c1ccc(NC(=O)c2cn[nH]c2)c(Cl)c1 +Cc1ccc2c(c1)c(=O)c(C(=O)Nc1cnn(C(C)C)c1)nn2C +O=C(c1ccnc(-c2ccc(Cl)cc2Cl)c1)N1CCOCC1 +O=C1OC(N2CCN(Cc3ccccc3)CC2)c2ccccc21 +Cc1ccc(NC(=O)NCCC(=O)N2CCCCC2)cc1F +COCc1nc(C)c(C(=O)Nc2ccc(C(C)(C)C)nn2)s1 +Cc1ccc(C(=O)c2c(C)[nH]n(-c3ccccc3)c2=O)cc1 +O=C(COc1ccc2ncccc2c1)N1CCc2ccccc21 +CC(C)CCNC(=O)Cc1csc(NC(=O)C2CCC(=O)N2)n1 +CN(Cc1cnn(C)c1)S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +NC(=O)c1cnc(NC(=O)Cc2cccc3ccccc23)s1 +Cc1cc(CN(C)C(=O)c2cc(C3CC3)on2)no1 +O=C(NCc1ccco1)NCC1Cc2ccccc2O1 +CCc1nnc(SCc2cccc(NC(=O)OC(C)(C)C)c2)n1N +Cc1ccncc1NC(=O)CSc1nc2ccccc2s1 +CC(=O)Nc1cccc(NCCn2nc3ccccn3c2=O)c1 +c1ccc(Cc2nnc(SCc3noc(-c4ccco4)n3)o2)cc1 +CC(C)n1nccc1NC(=O)Cc1noc2ccccc12 +CC(=O)Nc1ccc(SCC(=O)Nc2c(C)cccc2C)cc1 +Cc1ccc(NC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1C +CC(OCC1CCCO1)C(=O)NCc1nc(-c2ccncc2)cs1 +CCn1nnc2cc(C(=O)OCC(=O)NCc3cccs3)ccc21 +CC1CC(C)CN(C(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)C1 +CCc1nc2cccnc2n1C1CCN(C(=O)Nc2ccccc2)C1 +Cc1cccc(CNC(=O)NCC2CN3CCCCC3CO2)c1 +Cn1ccnc1S(=O)(=O)CC(=O)NCC1CCCCC1 +Cc1cc(=O)oc2cc(OCC(=O)N3CCC(C)CC3)ccc12 +CN(C)C(=O)c1cc(NC(=O)C2CC3CCC2O3)ccc1Cl +CC(C(=O)NCCOc1ccccc1)c1ccsc1 +Cc1nc2ccc(NC(=O)c3ccc(F)cc3F)cc2s1 +COCCn1c(S(=O)(=O)C(C)c2ccccc2)nc(C)c1C +N#Cc1cccc(NC(=O)c2ncc3ccccn23)c1 +Cc1noc(C)c1C(C)NC(=O)CCCc1cccs1 +O=C(CNC1(c2ccccc2)CC1)NCC(F)(F)F +Cc1ccc2cnn(CCCNC(=O)c3cccc(C#N)c3)c2c1 +COc1ccc(Br)cc1NCC(=O)N1CCC(C)CC1 +CC(=O)N(CCc1ccccc1)CC(=O)NCc1cccc(C)n1 +COCCCNC(=O)c1ccc(-n2nc(C)cc2C)cc1 +Nc1cn2nc(-c3ccc(F)cc3F)sc2n1 +CC(C)(C)C(=O)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 +Cc1cccc(NC(=O)c2cc(S(=O)(=O)N3CCCC3)c(C)o2)c1 +CC(=O)Nc1cccc(NC(=O)NC(C)(C)c2nc(C)c(C)s2)c1 +COc1ccc(CCC(=O)N2CCCC(O)(CO)C2)cc1OC +CCc1nnc(NC(=O)Nc2cccs2)s1 +O=C(CN1CCN(c2ccc(F)cc2)CC1)NCC(F)(F)F +Cc1cc(NC(=O)CCc2ncc(-c3ccc(Cl)cc3)o2)n(C)n1 +CCCC(=O)NCc1ccc(-n2ccnc2C)cc1 +CC(C)N(C(=O)C1CCN(C(=O)OC(C)(C)C)C1)C1CCC1 +CCN(CC)C(=O)CCNS(=O)(=O)c1ccc2c(c1)CCCC2 +c1ccc(-c2c[nH]c3c(N4CCCCC4)ncnc23)cc1 +CC(C)CCC(C)NC(=O)c1cc(Cl)ccn1 +C=CCn1c(SCCC(C)C)nc2c1c(=O)[nH]c(=O)n2C +CCN(CCO)c1ncnc(Nc2cc(Cl)ccc2C)c1N +CCC1CN(C(=O)CSc2nncn2-c2ccccc2C)CCO1 +N#Cc1ccccc1CN1CCc2cc(S(N)(=O)=O)ccc21 +COCC(=O)N1CCN(C(=O)c2cccc(Cl)c2Cl)CC1 +CN(C)c1ccc(C(=O)N2CCCC2c2ccncc2)cc1F +COCC(NC(=O)c1cccc(C)c1O)C(N)=O +CC(=O)c1ccc(OCC(=O)NCCC2=CCCCC2)cc1 +O=C(NCCc1ccccn1)c1cc(-c2ccco2)nc2ccccc12 +CC(=O)Nc1ccc(-c2cn(C(C)Cc3cc(C)n[nH]3)nn2)cc1 +COc1c(F)cc(NC(=O)NCc2ccnn2C)cc1F +Cc1ccc(Cl)c(OC(C)C(=O)NCC2CC2)c1 +CN1C(=O)c2ccccc2NC1c1cnn(-c2ccccc2)n1 +COc1cc(CNC(=O)C2Oc3ccccc3OC2C)ccn1 +Cc1ccccc1NC(=O)COc1ccccc1O +O=C1CCC(COC(=O)CCc2ccc(Cl)cc2Cl)N1 +Cc1noc(CNS(=O)(=O)c2ccc(Br)cc2)n1 +O=C(NC1CC1)c1cc(-c2ccc(Cl)cc2)on1 +Cc1ccc(C)c(C(=O)CSc2ncnc3c2cnn3C)c1 +Cn1c(=O)ccn(CC(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)c1=O +CC(C#N)CN1C(=O)C2(CCCC2)Nc2ccccc21 +COCC(NC(=O)CCn1cc(Br)ccc1=O)C(N)=O +CC(C)(C)c1noc(CCC(=O)Nc2cccc3cnccc23)n1 +CCCNC(=O)COc1cc(C(F)(F)F)c2c(C)nn(C)c2n1 +CCOc1ccc2c(C(=O)Nc3ccccc3OC)cc(=O)oc2c1 +COCc1cc(CNC(=O)c2scnc2C2CC2)ccc1F +CC(OC(=O)c1ccccc1)C(=O)NC1CCCC1 +CCOC(=O)C1CCC(=O)N1c1cc(Cl)ccc1OC +CN(Cc1ccccc1)C(=O)Cc1nc(CO)cs1 +CCCNC(=O)CNC(=O)Nc1ccccc1OC(F)(F)F +CN(Cc1ccccc1)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +Cc1nn2c(=O)c3c([nH]c2c1-c1ccccc1)CCCC3 +COc1cn(-c2ccc(F)cc2)nc1C(=O)NCc1cccs1 +CCNC(=O)c1ccc(NC(=O)NCCC2=CCCCC2)cc1 +CCC(=O)N1CCCC1c1csc(Nc2ccccn2)n1 +CCCC1COCCN1C(=O)Cn1c(=O)oc2ccccc21 +CCN(CC)c1ncc(CN2CCOC(C)(C)C2)s1 +CCN1CC2(CCC1=O)CCN(C(=O)CCn1cnnn1)CC2 +CCc1cccc2c1[nH]c1cc(NC(=O)CC#N)ccc12 +CCc1nc(C)c(C(C)N(C)CC2(CO)COC2)s1 +CSc1ccc(C(O)CNC(=O)c2ccc(C)c(C)c2)cc1 +Cc1cc(=O)c(C(=O)NC(C)C2CCCO2)nn1-c1ccccc1F +CC1(NC(=O)Cc2cccc(OCC#N)c2)CCOCC1 +O=C(COC1CCCCC1)NCc1ccccc1Cn1cncn1 +CCN(CC)C(=O)N1CCN(c2ccc(C#N)cn2)CC1 +Cc1csc(CNC(=O)NCc2cc[nH]n2)n1 +CN(C)S(=O)(=O)N1CCCC1Cc1ccccc1Cl +O=C(NCCOc1ccc(C(F)(F)F)cc1)NCc1ccncc1 +NC(=O)C1CCCN(C(=O)CCSc2ccc(Cl)cc2)C1 +CC(OC(=O)c1cc(Cl)c2c(c1)OCO2)C(=O)NC1CCCC1 +CCc1n[nH]c(SC(C(=O)Nc2ccc3c(c2)CCC3)C(C)C)n1 +O=C(CCc1ncn[nH]1)NCC1C2CC3CC(C2)CC1C3 +Cc1nc(C)c(CC(=O)Nc2cccc3ccccc23)s1 +Cc1cccc(C)c1NC(=O)C1(c2cc(-c3cccs3)on2)CC1 +CCOCCOC1CCN(C(=O)Nc2c(C)noc2CC)C1 +Cc1cccc(C(=O)Nc2ccc(CC(=O)NC(C)C)cc2)c1O +CNS(=O)(=O)c1ccc(C(=O)Nc2ccc(SC)cc2)cc1 +Cc1cc(CN(C)C(=O)COc2ccccc2)no1 +CC(=O)Nc1ccc(OCC(=O)NCc2cc(F)ccc2F)nc1 +Cc1nc(-c2ccccc2)sc1C(=O)Nc1cccnc1C(N)=O +CC1CN(C(=O)c2cc(-c3ccccc3Cl)[nH]n2)C(C)CO1 +CN(CCc1ccncc1)C(=O)c1sccc1OC(F)F +Cc1ccc(C(CC(=O)OC(C)C)NC(=O)c2ccccc2)cc1 +COc1ccc(-c2c(C)nc3ncnn3c2N)cc1 +CC(Cn1cncn1)NS(=O)(=O)CCc1ccccc1 +Cc1ccc(NC(=O)N2CCCCC2C(C)C)cc1S(C)(=O)=O +COCCNC(=O)CCc1nc(-c2ccc(F)cc2)no1 +Cc1ccc(C(C)NC(=O)NC(C)Cc2cccs2)o1 +COCC1CCCN(C(=O)CCn2ccc(=O)[nH]c2=O)C1 +COc1ccc(F)cc1C(=O)NCC(C)(C)c1ccncc1 +Nc1ccc2c(c1)N(CCCCOc1ccccc1)CCO2 +COc1ccccc1CNC(=O)c1nn(-c2ccccc2)c2c1COC2 +O=C1CCC(C(=O)NCC#CCOc2cccc(C(F)(F)F)c2)N1 +CCc1ccc(-c2n[nH]c(SC3CCOC3=O)n2)cc1 +CCNC(=O)CNC(=O)Nc1ccc(Oc2cccnc2)c(C)c1 +N#Cc1ccc(CSc2nnc(-c3ccncc3)o2)c(F)c1 +COc1ccccc1CCn1c(C)c(C)c(C#N)c1N +COCn1nc(CO)cc1-c1ccc(OC)c(OC)c1 +CC(OC(=O)c1ccc2ccccc2n1)C(=O)NC1CCCC1 +COC(=O)C(C)n1ccc(=O)c2ccc(Cl)cc21 +CC(=O)NCc1nc2ccccc2n1CC(=O)Nc1ccccc1C +Cc1cc(C)c(NC(=O)c2cc3ccccc3c(=O)[nH]2)c(C)c1 +CCCCN(C)S(=O)(=O)N1CCOC(c2ccccc2)C1 +CC(C(=O)OCCC1CCCO1)N1CCc2ccccc2C1 +COc1cccc(N2C(=O)c3ccccc3NC2c2ncc[nH]2)c1 +O=C(NCC1CC1)C1CC2CN(c3ncccn3)CC1O2 +O=C(NCc1ccc(F)cc1)c1noc2c1CCc1ccccc1-2 +Cc1nsc(N2CCN(CC(=O)NCc3ccc(F)cc3)CC2)n1 +Cn1cc(C(=O)Nc2ccc(F)c(F)c2F)c(N)n1 +C#CCN1CCN(C(=O)NCC(=O)N2CCc3ccccc32)CC1 +COC(=O)c1ccccc1Nc1ncnc(Oc2cccnc2)c1N +Cc1nc2cc(NC(=O)N3CCOCC3)ccc2n1C +C=CCNC(=O)CN1CCN(c2ccccc2Cl)CC1 +CCNC(=O)Cc1ccc(NC(=O)NC(CC)CC)cc1 +O=C(CCCn1cccn1)N1CCCC(c2cn[nH]c2)C1 +CC(C)c1nc(CNC(Cc2ccccc2)C(=O)N(C)C)cs1 +Cc1cn2c(CN(C)C(=O)c3ccc(F)c(C)c3)c(C)nc2s1 +Cc1ccsc1C(=O)NCCNc1cnccn1 +Cc1cc(Cl)ccc1OCc1nnc(SCC(N)=O)n1C +COc1cc(N2CCc3nc(C)n(C)c(=O)c3CC2)nc(N)n1 +O=C(Nc1nncs1)NC1CCCc2[nH]c(=O)ccc21 +CCC1Oc2ccccc2N(CC(=O)N(C)CCC#N)C1=O +O=C(CCNC(=O)Nc1ccc(F)cc1F)NCc1ccccc1 +[H]N=c1n(CC)c2ccccc2n1CC(=O)C(C)(C)C +CC(C)COC(=O)CSc1nnc(-c2ccccc2O)n1N +NC(=O)C1Cc2ccccc2CN1Cc1nnc(-c2ccccc2)o1 +Oc1ccc(C2NCCc3ccc4cc[nH]c4c32)cc1 +CC(=O)Nc1ccc(C2NCCc3cc(F)ccc32)cc1 +CC1CCCN(C(=O)c2ccc(-n3cnnn3)cc2)C1 +COC(=O)COc1cccc(NC(=O)c2ccccc2Cl)c1 +Cc1ccc(C)c(S(=O)(=O)CCN2CCN(CC(C)O)CC2)c1 +Cn1nc2nc(NCC3CC3)nc(-c3cccc(F)c3)c2c1N +Cc1noc2nc(C(F)(F)F)c3c(c12)CCNC3 +Cc1cc(C)n(CC(C)CNC(=O)NCc2cc3ccccc3o2)n1 +CC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2ccc3c(c2)OCO3)c1C +CCCN(C)c1cc(CC)nc2nc(C(=O)OC)nn12 +Cc1nc(NC2CCCC2)c2c(C)c(C)sc2n1 +O=C(Cn1cnc2c(cnn2-c2ccccc2)c1=O)c1ccc[nH]1 +Cc1cccc(C)c1NC(=O)C1CN(c2nc3ccccc3s2)C1 +CCN(Cc1ccoc1)C(=O)NC(C)Cc1cccc(OC)c1 +O=C(NCc1ccncc1)c1c(F)c(F)c(F)c(F)c1F +N#CC(CCC(=O)Nc1ccccc1Cl)c1ccncc1 +CCN1C(=O)C(Cc2ccccc2F)Oc2cc(N)ccc21 +Cc1nc(CC(=O)Nc2ccc(C#N)c(Cl)c2)cs1 +CCC(Oc1ccc(C)cc1)C(=O)Nc1cc(N)ccc1OC +Cn1cccc1-c1cc(C(=O)N2CCCC2c2cccnc2)[nH]n1 +O=C(Nc1ccccc1C(F)(F)F)c1ccc(C(F)(F)F)nc1 +O=C(OCc1ccccc1)N1CCCC(c2cc3cccnc3[nH]2)C1 +c1cc(-c2ccc(SCC3OCCO3)nn2)ccn1 +CN(CCC#N)CC(=O)NCCc1ccc(F)cc1 +CCc1nc(CC(=O)N2CCCC(c3noc(C(C)C)n3)C2)cs1 +Cc1nc(CNC(=O)C2(C#N)CCCCC2)oc1C +Cc1cc2n(Cc3cccnc3)c3cc(N)ccc3n2n1 +CC1CCN(C(=O)c2ccc(NC(=O)c3ccccn3)cc2)CC1 +COc1ccc(C(=O)c2cccc(N)c2C)cc1OC +CC1CN(CC2CCCN2C(=O)COc2ccccc2)CC(C)O1 +Cc1cc(C(=O)Nc2ccc(Cl)cc2F)on1 +CC(C)Cc1cc(C(=O)N2CCCC2c2ccccn2)no1 +CCOCC(=O)N1CC(C)C2(CCN(Cc3cccnc3)C2=O)C1 +O=C1CC2CCC1CN2C(=O)OCc1ccccc1 +NC(=O)c1csc(N2CCOC(c3ccc(F)cc3)C2)n1 +CC(C)(C)OC(=O)N1CC(O)CC1C(=O)OCc1ccccc1 +CC(=O)Nc1nc(CSc2nnnn2C2CC2)cs1 +O=C(Cn1cc(Cl)cn1)NC1CCC2CCCC21 +CC1(C)CCCN1C(=O)C1CCCN(C(=O)c2ccc(F)cc2)C1 +CC(c1cccc(Cl)c1)N(C)C(=O)c1cnns1 +CC1CN(C(=O)c2cc(F)c(F)c(F)c2)CC(C)O1 +O=C(Cn1cnc2ccc(F)cc2c1=O)Nc1nncs1 +CCOc1ccc(-n2nc(N3CCOCC3)cc2N)cc1 +CCc1c(C(=O)N2CC(C)OC(C)C2)csc1C +Cn1c(CO)cnc1SCCC(=O)Nc1cc(F)cc(F)c1 +NC1=NC(=O)C(Cc2ccc3c(c2)OCO3)(c2ccc(Cl)cc2)N1 +CCOC(=O)N1CCC(Nc2nc(C)cc(C)n2)CC1 +COC1CCC(CC(=O)Nc2cc(C)c(Br)cn2)CC1 +COCc1cccc(C(=O)N(C)Cc2cccc(C#N)c2)c1 +CCn1c(C(CC(C)C)NC(=O)COC)nc2cccnc21 +CCOc1ccccc1C(=O)N(C)Cc1ccccc1F +COc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cc1 +CC(C)CN(CC(F)(F)F)C(=O)c1ccc2c(c1)OCCO2 +Cc1cc(CN(C)C(=O)c2cc(C(C)(C)C)n[nH]2)no1 +COc1cccc(CNC(=O)c2ccc(C)c(F)c2)c1 +CCCCn1cc(O)c(=O)cc1CN1CCN(CCO)CC1 +COc1ccc(S(=O)(=O)Nc2ccccc2OC)cc1F +CC(C)(C)OC(=O)N1CCCC(NCC(=O)c2ccccn2)C1 +Cc1cc(C(=O)NCCn2nc(C(F)(F)F)cc2C2CC2)no1 +CC(C)(C)OC(=O)N1CCCC1C(=O)NCc1ccccn1 +CCOC(=O)C1CCCN1C(=O)c1sccc1CC +Cc1ccc(C(=O)Nc2cccc(F)c2C#N)c(C)c1 +CCNC(=O)c1ccc(CNC(=O)c2cccc(C#N)c2)cc1 +COc1ccc(CNC(=O)c2cc(OC)c(OC)cc2C)cc1 +COc1cc(C(=O)OCC(=O)Nc2cc(C)ccc2OC)ccn1 +CCOc1c(Br)cc(C(=O)NCCCO)cc1OC +COc1cc(C(=O)N2CCN(c3ccccc3)C(=O)C2)ccn1 +CC(Cn1ccnc1)NS(=O)(=O)c1cccc(OC(F)(F)F)c1 +CCOCCCNC(=O)N1CCC2(C1)C(=O)Nc1ccc(OC)cc12 +Cc1ccc(C(C)NCC(O)c2cccc(F)c2)o1 +Cc1cc(C(O)CNCc2ccc(F)cc2)ccc1F +Cc1cc2nc(CO)n(CC(=O)N(C)c3ccccc3)c2cc1C +Cn1ccc(Nc2c(C#N)nnc3ccccc23)n1 +O=C(Nc1cccc(S(=O)(=O)N2CCCC2)c1)c1cccs1 +COc1ccccc1CNC(=O)Cn1nc(-c2ccco2)ccc1=O +CN1C(=O)C(c2ccccc2)CC12CCN(C(=O)c1ccco1)CC2 +CCOC(=O)Nc1cc2c(C)cc(=O)oc2cc1C +Cc1cc(C(F)(F)F)nc(CNc2nccc(-c3ccccn3)n2)n1 +CC(C)(NC(=O)NCc1cccnc1)c1nccs1 +C#Cc1cccc(NS(=O)(=O)c2ccc(C)s2)c1 +CC(Cn1cccn1)NC(=O)Cc1csc(N2CCCC2=O)n1 +Cn1cc(C2CN(S(=O)(=O)c3cccs3)CCO2)cn1 +O=C(Nc1ccccc1)C1CCCN1C(=O)c1ccccn1 +Cc1nc(-c2ccc3c(c2)NCC(C)(C)O3)c(C)s1 +CC(=O)N1CCCN(C(=O)NCc2cc[nH]n2)CC1 +O=C(NCC(O)c1ccc(F)cc1)c1cnc2sccn2c1=O +CCCC1CCN(C(=O)c2cccc(C#N)c2)CC1 +COC(=O)CCNC(=O)C(N)c1cc(C)cc(C)c1 +CN1C(=O)CCc2cc(NC(=O)c3c[nH]c4ccccc4c3=O)ccc21 +CC(=O)Nc1cccc(OCCNC(=O)N(C)C(C)C)c1 +CCOC(=O)Nc1cccc(C(=O)Nc2ccc(F)c(F)c2)c1 +COc1ccccc1C(C)(C)CNC(=O)N1CCC(C(N)=O)CC1 +Cc1noc(NC(=O)CCNC(=O)c2ccc3ccccc3c2)n1 +CCc1cccc(C)c1NC(=O)Cn1ccc(=O)n(C)c1=O +Cc1csc(CCNc2cnn(Cc3ccccc3)c2)n1 +COc1cc(C(C)=O)ccc1OS(=O)(=O)c1cc(F)ccc1F +CC(C)n1cnnc1SCC(=O)Nc1ccn[nH]1 +C=C(C)Cn1c(CNC(=O)CC)nc2ccccc21 +CS(=O)(=O)c1ccccc1NCC(O)c1ccccc1F +Cc1nn(C)cc1NCc1ccc(OCC(C)C)cc1 +CCOC(=O)Cc1csc(NC(=O)c2ccc3ccccc3n2)n1 +O=C(N1CCOCC1)N1CCC(c2nc3ccccc3[nH]2)CC1 +COc1ccc2c(c1)CCCC2Nc1cc(C)nc(N)n1 +COCCn1c(=O)c2sccc2n(CC(=O)NC(C)C)c1=O +COC(=O)CCNC(=O)c1cc(OC)ccc1O +N#Cc1cccc(NC(=O)COc2ccccc2N)c1 +COc1ccc(C(=O)N2CCN(CC(C)C#N)CC2)cc1 +O=S(=O)(NCc1cccnc1)c1ccc2c(c1)NCCO2 +NC(=O)c1ccccc1OCc1noc(C(=O)NC2CCCCC2)n1 +O=C(OCc1nnc(-c2ccccc2)o1)c1cc(-c2ccccc2)on1 +Cn1cc(CN2CCN3C(=O)N(c4ccccc4)CC3C2)cn1 +COCC(NC(=O)c1sc(C)nc1CC(C)C)C(N)=O +COCCc1noc(N)c1-c1ccc(Br)cc1 +CCCCc1nc(CNc2ccn(-c3ncccc3Cl)n2)no1 +CC1c2ccsc2CCN1S(=O)(=O)c1ccc(C(N)=O)cc1 +COC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2cnn(C)c2)c1C +CCN(CC)C(=O)c1csc(NC(=O)c2ccc(F)c(F)c2)n1 +C=CCn1c(=O)c2ccccc2n2c(SC(C)C#N)nnc12 +CCC(O)Cn1ncnc1CCNS(C)(=O)=O +Cc1cc2nc(C(C)C)c(CO)n2cc1Br +CCn1c(CCNC(=O)c2ccco2)nc2ccccc21 +Cn1cnnc1SCCNC(=O)OCC(F)(F)F +CCCOc1ccc(OC)c(-c2cc(C(=O)OC)[nH]n2)c1 +CCCNC(=O)Nc1ccc(OC)c(OC2CCCC2)c1 +O=C(CN1C(=O)c2cccc3cccc1c23)NCCCn1ccnc1 +COc1ccc(N)cc1CNS(=O)(=O)c1cn[nH]c1C +COc1ccc(NC(=O)c2ccc(F)cc2Cl)cn1 +NS(=O)(=O)N1CCCN(c2nc3ccccc3s2)CC1 +Cc1ccc(OC(C)C(=O)N2CCN(C(=O)CO)CC2)cc1 +COCc1cccc(NC(=O)NCC(=O)OC(C)C)c1 +Cc1noc(C)c1CN1CCN(C(=O)CCNc2ccccc2)CC1 +CC(=O)N1CCc2cc(NC(=O)c3ccc(=O)n(C)n3)ccc21 +COc1ccc(C(=O)Cn2cnc3ccc(Cl)cc3c2=O)cc1 +O=C1CCc2cc(C(=O)CSc3nnc(C4CC4)o3)ccc2N1 +COC1CCC(c2cnc3ccccc3c2)n2nc(N)nc21 +Cc1nc(-c2ccc(CNC(=O)C3CC=CCC3)cc2)cs1 +CCC1CCCN(C(=O)c2cnc3ccccn3c2=O)C1 +COc1cc(C(C#N)N2CCOCC2)ccc1OCc1ccccc1 +Cc1ccc(C(C)(C)C)cc1C(=O)C1CCC(=O)O1 +O=C(NCC1CC=CCC1)C1CCCN1S(=O)(=O)c1ccccc1 +CC(=O)Nc1ccc(NC(C)C(=O)Nc2ccc(F)c(F)c2)cc1 +Cc1ccc(S(=O)(=O)NCc2ccco2)cc1C(=O)NCCO +CCc1ccc(NC(=O)Cc2nc(-c3ccccn3)n[nH]2)cc1 +N#Cc1ccc(NC(=O)Nc2cccc(Cn3cccn3)c2)cc1 +O=C(Cc1ccccc1F)OCC1COc2ccccc2O1 +COc1cc(C(=O)N2CCC(O)(C(F)(F)F)C2)ccc1OC(C)C +CCCN(C)C(=O)CCC(=O)Nc1nccs1 +O=S(=O)(c1ccc(N2CCOCC2)cc1)N1CCOCC1 +CN(CCO)C(=O)c1ccc(-c2ccc(Cl)cc2)o1 +CC(=O)Nc1ccc(-c2n[nH]c(-c3ccc(Cl)c(N)c3)n2)cc1 +O=C(NCCO)c1cc2c([nH]c3ccccc32)c(-c2ccccc2)n1 +O=C(CSc1nc(-c2cccs2)n[nH]1)c1ccccc1 +COc1cccc(N2CC(c3nc(C)no3)CC2=O)c1 +CCN(CC(=O)Nc1ncccc1C)c1ccccc1 +CC(=O)Nc1cc(C(=O)N2CCCC2Cc2ccccc2)ccc1C +CCOC(=O)Cn1nc(C)cc1NC(=O)c1ccccc1F +CC1CCCC1NC(=O)c1ccccc1CSc1ncn[nH]1 +Cc1nc2ccc(NC(=O)NCCOc3cccc(F)c3)cc2o1 +O=C(Nc1cccc(Br)c1)c1ccc(=O)oc1 +COc1ccc(-c2nc(NC(=O)c3sccc3C)n[nH]2)c(OC)c1 +CC(C)CCc1nc(CNC(=O)c2ccccc2)cc(=O)[nH]1 +CCCn1nc(C)c(C(=O)N2CCC3(CC2)OCC(C)O3)c1C +Cc1nc(C(N)c2ccc(F)cc2N)sc1C +CCCC(C#N)(CCC)C(=O)NCc1nccn1C +CCN(CC)C(=O)c1ccc(Nc2ncnc3ccsc23)cc1 +Nc1nonc1C(=O)NCCCOCc1ccco1 +O=C(c1ccc(F)cc1)N1CCC(S(=O)(=O)c2ccccc2)CC1 +CCc1nn(CC(=O)NCc2ccccc2)c(=O)c2cccn12 +NC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccccc3)C2)cc1 +Cc1sc(C(=O)N(C)C)cc1-c1ccc(F)cc1 +COCCCn1c(C)cc(C(=O)CN2C(C)COCC2C)c1C +C#CCCN1CCN(C(=O)c2ccc(OC)c(OC)c2)CC1 +CC(=O)NCCNC(=O)N1CCC(NC(=O)c2ccccc2)CC1 +CCN1CCN(C(=O)C2(C)Oc3ccccc3NC2=O)CC1 +CC(C)CC(C)OC(=O)Cn1cnc2c(cnn2C)c1=O +N#CC1CN(CCCc2ccc(Cl)cc2)CCO1 +CC1=Nn2c(nnc2C(F)F)SC1=Cc1cnc2ccccc2n1 +COC(=O)c1cnn(-c2c(C)cc(C)cc2Cl)c1N +Fc1ccc(-c2ncccn2)cc1Br +O=C(c1csc(S(=O)(=O)NCc2ccco2)c1)N1CCCC1 +Cc1cccc(C(C)C)c1NC(=O)C(O)c1ccc(F)cc1 +CC(C)c1noc(CCC(=O)Nc2ccc(F)cc2)n1 +CC(=O)Nc1ccc(F)c(NC(=O)CNC(=O)C(C)(C)C)c1 +CSc1cccc(NS(=O)(=O)c2ccccc2)c1 +Cc1cc(C(=O)N2CCN(Cc3ccncc3)CC2)c(C)n1C(C)C +CCOC(=O)c1c(C)csc1NC(=O)Cc1ccc(OC)cc1 +Cc1cc(Cl)ccc1OCCCN1CCCS1(=O)=O +N#Cc1cc(C2NCCc3c(N)cc(F)cc32)ccc1F +N#Cc1ccc(-c2cc(NCc3ccccn3)nc3[nH]ccc23)nc1 +Cc1cccc(C(=O)NCc2nnc(C(C)C)n2C)c1Cl +COCC1CCCN(C(=O)NCC(C)Oc2ccccc2)C1 +CC(C)(C)C(NC(=O)Nc1ccc(F)nc1)C(N)=O +COCCN(Cc1ccsc1)S(=O)(=O)c1ccc(C)s1 +CC(=O)NCCNC(=O)NC(C)c1ccc(C(C)(C)C)cc1 +CCc1ccc(NC(=O)C(C)S(=O)(=O)c2ccccc2)cc1 +COc1ccc(NC(=O)Nc2ccc(C#N)cc2)cc1F +CC(N)C(=O)c1ccc2c(c1)CC(C)N2S(C)(=O)=O +CCOC1CCCN(C(=O)c2cc3cnn(C(C)C)c3nc2C)C1 +NC(=O)c1ccc(CNc2cccc(Cl)c2)c(F)c1 +C=CCNS(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +Cc1nc(NC(=O)c2scnc2C2CC2)sc1SCC#N +CCC(C)(C)NC(=O)CN1CCn2cccc2C1C +O=C(Nc1ccc(Cl)cn1)C1Cc2ccccc2C1 +NC(=O)c1ccc(NCc2noc(-c3ccoc3)n2)cc1Cl +COc1cc(C(=O)Nc2ccn(C)n2)cc(OC)c1Br +OCCn1c(C2CC2)nc2cc(Br)cnc21 +NC(=O)c1cc(N)c(N2CCOCC2)c(Cl)c1 +Cc1ccccc1OCC(=O)N1CCOc2ccc(F)cc21 +Cc1ccc(C)c(OC2CCN(C(=O)c3n[nH]c4c3CCC4)CC2)c1 +CCC(=O)Nc1nnc(C2CC(=O)N(c3ccc(Cl)cc3)C2)o1 +COc1ccccc1-n1nc(-c2ccccc2)cc1N +Nc1c(C(=O)NC2CCCC2)nnn1-c1ccccc1Cl +O=C(NCCN1CCOCC1)Nc1nnc(C2CCCCC2)s1 +CC(C)Oc1nccc(OC(C)(C)C)c1OC1CC1 +COc1ccc(CCN2C=CC(C#N)C=C2)cc1OC +O=C(N=c1[nH]c2ccccc2[nH]1)c1cnc2sccn2c1=O +COCC(C)N1CCN(C(=O)Nc2ccccc2C(F)(F)F)CC1 +O=C(NC1CC1)c1cnn2c(-c3cccs3)ccnc12 +Cc1nn(C)c(C)c1NC(=O)c1cc(Cl)ccn1 +COC1CCCCC1OC(=O)CCN1C(=O)CCc2ccccc21 +COCc1ccc(CNC(=O)CCn2cc(C)cn2)cc1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)NCC(=O)NC2CC2)c1 +COc1ccc2nccc(NC(=O)c3ccoc3C)c2c1 +COCc1nc(C(=O)N(CCc2cccc(F)c2)C2CC2)cs1 +CN(C)c1ncc(Br)cc1C(=O)N1CCOCC1 +Cc1sc(NC(=O)c2cccnc2)c(C#N)c1-c1ccccc1 +COc1ccc2cc(CN(C)C(=O)c3ccc4c(c3)OCO4)ccc2c1 +C=CC(C)Sc1n[nH]c(=O)n1CCc1ccccc1 +COc1ccc(N)cc1-n1cc(-c2cc(F)ccc2F)nn1 +NC(=O)C(NCc1ccccc1Cl)c1ccccc1 +Cc1cc(NC(=O)CCn2cnc3ccccc32)no1 +CCn1c(C)cc(C(=O)N2CCN(C3CCCC3O)CC2)c1C +Cc1cc2n(n1)C(c1cccs1)Nc1ccccc1-2 +COC1(CNC(=O)c2c(C)cc(C)cc2C)CCOCC1 +COCCCNC(=O)NC(c1ccc(Cl)cc1)c1nccn1C +CCCCS(=O)(=O)NCC(=O)N1CCCC1c1ccc(F)cc1 +COCCN1C(=O)c2ccccc2NC1c1c(F)cccc1F +CC(OC(=O)C1CCOCC1)C(=O)Nc1cccc(Cl)c1Cl +CC(C)(C)CC(=O)NCc1nc(-c2ccccc2)no1 +CN(C)C(=O)c1cn(Cc2ccccc2)nc1-c1ccc(Cl)cc1 +CCc1ccccc1OCC(=O)Nc1ccc(S(C)(=O)=O)cc1 +CC(C)(C)OC(=O)N1CCN(C(=O)OC(C)(C)C)C(CCO)C1 +CC(C(=O)N1CCN(C2CCCC2O)CC1)n1cccn1 +CC(c1nncn1C(C)C)n1cc(CCc2ccccc2)nn1 +CC1(C)CCN(S(=O)(=O)c2c(N)cccc2Cl)CC1 +COC(C)CCC(=O)Nc1sc(C)cc1C(N)=O +CN(Cc1cnn(-c2ccccc2)c1)C(=O)Nc1ccc(Cl)cc1 +O=C(NCC1CCC(c2nc3ccccc3[nH]2)CC1)c1cccnc1 +CCC(C(=O)NCc1nn(C)c(=O)c2ccccc12)c1ccccc1 +Cc1csc(C2CCCN(Cc3cnc4c(C)cccn34)C2)n1 +CN(C)c1ccc(NC(=O)c2ncccc2OCC(F)(F)F)nc1 +CN(C)C(=O)CSc1ccccc1C(=O)Nc1ccn[nH]1 +COCCOC(=O)c1cc(Cl)ccc1OC(C)C +Fc1cccc(-n2c(C3CC3)nc3cccnc32)c1 +CC(=O)N1c2ccccc2CC1C(=O)NCC(C)(C)c1ccncc1 +Cn1c(SCC(=O)Nc2sccc2C#N)nnc1C1CCCC1 +CC(C(=O)C(C#N)c1ccc(F)cn1)N1CCc2ccccc2C1 +CCc1cc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)sc1C +O=C(CSc1ccccn1)NCC(=O)c1ccccc1 +CC1(COC(=O)C2CCN(c3nc4ccccc4o3)CC2)COC1 +Cc1cc(NC(=O)C(C)NC(=O)c2ccccc2)c2ncccc2c1 +CCCn1nccc1NC(=O)Cc1c[nH]c2ccc(OC)cc12 +CS(=O)(=O)c1ccsc1NC(=O)c1ccccc1 +O=C(NCc1ccco1)c1cc2cc(F)ccc2o1 +Cc1cc(C(=O)NCCC(=O)NC2CCCC2)c(C)n1C(C)C +Cc1c(NC(=O)c2c(F)cccc2F)cnn1C +CCCCCNC(=O)c1ccc(CN2CCOCC2)cc1 +CCC1c2ccccc2CCN1C(=O)Cn1ncc2ccccc2c1=O +COc1cccc(C(=O)Nc2cnn(C3CCOCC3)c2)c1 +COC(=O)c1c(C)nn2c1ncc1c(=O)n(CC(C)C)ccc12 +COC(=O)C1C(c2ccc3c(c2)OCO3)c2c(O)n[nH]c2CC1(C)O +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)NCc1nnc2n1CCC2 +O=C(Nc1nc2ccccn2n1)NC(CCCO)c1ccccc1 +Cc1n[nH]c(C)c1NC(=O)c1cc(F)ccc1F +Cc1ccc(NC(=O)N(C)CC(C)C#N)cc1Cl +Cc1cccc(-c2nn(-c3ccc(F)cc3)cc2C(=O)N(C)C)c1 +Nc1nccnc1C(=O)N1CC=C(c2ccc(O)cc2)CC1 +CCCN(C)c1ccc(C(=O)NC2CCCC2C(=O)NC)cc1 +CCOC(=O)N1CCN(C(=O)NCc2ccccn2)CC1 +COc1cccc(C(=O)NCC(O)(c2cccs2)C2CC2)c1OC +O=C(CN1C(=O)COc2ccccc21)Nc1cccc(F)c1 +Cc1cc(CN(C)C(=O)c2ccc(OCC(F)F)nc2)no1 +Cc1noc(CNC(=O)Cc2noc3ccccc23)n1 +Cn1cnnc1SCC(=O)NCc1ccc(Cl)cc1 +Cc1nn2c(C(F)(F)F)cc(-c3cccs3)nc2c1C#N +C=CCOc1cccc(C(=O)Nc2ccc3c(c2)OCCO3)c1 +Cc1cc(C(C)NC(=O)NC(C)c2nc3ccccc3[nH]2)c(C)s1 +NC(=O)CN(Cc1ccccc1)C(=O)c1cccc(C(F)(F)F)c1 +COc1ccc(NC(=O)CN2CCN(c3ccccc3F)C2=O)cc1 +NC(=O)N1CCCC(C(=O)NCc2cccnc2)C1 +O=C(CN1CCN(Cc2ccccc2Cl)CC1)c1cccs1 +Cc1cc(C)c(NCC(=O)NC(C)(C#N)C(C)C)c(C)c1 +CC1(C)OCC2(CO1)CN(S(=O)(=O)Cc1ccc(F)cc1)C2 +O=C(CCc1ccc(Cl)cc1)NCCNC(=O)c1ccc(F)cc1 +CC1CCCN(S(=O)(=O)N2CCCC2c2ccccc2Cl)C1 +CN(CCC(F)(F)F)C(=O)NCCNC(=O)C1CC1 +Cc1ccc(-c2c(C)sc3nc(C)n(CCC#N)c(=O)c23)cc1 +COc1ccc(CNC(=O)CCc2c(C)noc2C)cc1OC +OCCN(CCc1ccccc1)c1ccc(O)cc1 +O=C(NC1CCCOc2ccc(F)cc21)c1cc[nH]n1 +COCc1nnc(SCC(=O)Nc2ccccc2Cl)n1N +Cn1c(SCC(=O)NCc2ccccc2F)nnc1C1CC1 +Cc1nc2c(s1)CCCC2NC(=O)Nc1cnns1 +CCC(C)NC(=O)C(C)NC(=O)Nc1cccc(Cl)c1 +Cc1ccc(N)c2nnc(CCc3ccccc3)n12 +CC(=O)Nc1ccc(CC(=O)N2CCOC(c3ccccc3)C2)cc1 +CC(NC(=O)NC1CCN(c2ncccn2)CC1)C1CCCO1 +COc1cccc(OCc2cc(C(=O)NC(C)C(N)=O)n[nH]2)c1 +CCC(C)(NC(=O)Cc1coc(-c2cccs2)n1)C(=O)OC +COc1ccc(CCNC(=O)Cc2c(C)noc2C)cc1 +O=c1[nH]c(COc2ccccc2Br)nc2ccsc12 +COc1cccc(OCc2nc(C(=O)NC(C)(C)CO)co2)c1 +Cc1nc2cc(Cl)ccc2cc1C(=O)NCc1cccnc1 +C#Cc1cccc(NC(=O)c2c(C)oc(C)c2C)c1 +C#CCNC(=O)c1cnn(-c2cccc(Cl)c2)c1C(C)C +CCCN(Cc1ccc(C#N)cc1)C(=O)c1cn2cccnc2n1 +Cc1cccc(C(=O)N2CCn3c2nc2ccccc23)c1 +CC1CN(C(=O)c2cccnc2OCC(F)F)c2ccccc21 +Cc1nnc(N(C)CC2CCCN2c2cccnn2)c(C#N)c1C +Cc1cccc(C(=O)N2CCN(c3ccccc3F)CC2)c1O +CCN(CC)S(=O)(=O)N1CCC(C(=O)N2CCN(C)CC2)CC1 +Fc1ccc2c(c1)nc(-c1ccncc1)n2-c1ccncc1 +CCN1CCN(C(=O)C(C)Sc2nc(C)cc(C)c2C#N)CC1 +O=C(Cc1ccc(-c2nn3cnnc3s2)cc1)N1CCCC1 +CC(CC#N)Sc1ccccc1NCC(=O)Nc1cccc(F)c1 +Cc1ccc(C(=O)N2CCCC2c2ccc(F)cc2)c(=O)[nH]1 +Cc1[nH]c2ccccc2c1C(=O)N1CCC(CC(N)=O)CC1 +CCC(CO)Nc1cc(C)c(C#N)c2nc3ccccc3n12 +Cc1ccnc(Oc2cccc(C(=O)NCc3cccnc3)c2)n1 +Cc1nc(CC(=O)NCCOc2ccc(C(C)(C)C)cc2)cs1 +OCCCN(Cc1ccc2c(c1)OCO2)c1ccc(F)cc1 +COc1ccc2nccc(NC(=O)c3ccccc3)c2c1 +CC(C)Cc1cc(C(=O)NCCn2cnc3ccccc32)[nH]n1 +Cc1cccc(C(=O)Cc2ccnc3cc(Br)ccc23)n1 +CCC(CC)N(C)C(=O)c1cc(C)c2c(=O)n(C)c(=O)n(C)c2n1 +CCc1nnc2c(NCc3ccccc3)nc3ccccc3n12 +CC1Cc2ccccc2N1C(=O)CSc1nnnn1C(C)C +Cc1ccccc1CN(C)C(=O)c1cccnc1Oc1cccnc1 +O=C(COc1ccccc1)NCC#CCOc1ccc2c(c1)OCO2 +Cn1cc(CNC(=O)c2ccc3c(c2)OCO3)cn1 +Cc1ccc(C)c(NC(=O)C2CN(C(=O)c3cccs3)C2)c1 +O=C(NCCc1ccccc1)C1COC(=O)N1Cc1cccnc1 +CCCCCNC(=O)c1nn(-c2ccc(Cl)cc2)nc1CO +Cc1ccc(S(=O)(=O)NC(C)C)cc1C(=O)Nc1cccnc1 +COCCn1cc(C(=O)N2CCOC3CCCC32)c2ccccc21 +CC(C)(O)C#Cc1ccc(C(=O)NCc2ccncc2)cn1 +CC1CCCN(C(=O)CSc2nc3ccccc3[nH]2)C1 +Cc1csc(NC(=O)c2cn(C)c3ccc(F)cc3c2=O)n1 +CCN(CC)c1ccc(NC(=O)CCc2nc3ccccc3[nH]2)cn1 +COc1cccc(-c2cc(C#N)nn2CCCC(N)=O)c1 +Cc1ccn(-c2ccc(NCCNC(=O)C3CCCC3)nn2)n1 +O=C(Cn1nnc2ccccc2c1=O)NC1CCCCC1 +COC1CCCC(OC(=O)CCc2cnn(-c3ccccc3)c2)C1 +Cc1nn(-c2ccccc2)c2[nH]c(=O)cc(C(F)F)c12 +CN(C)c1nc(CNC(=O)Nc2ccc3c(c2)COC3)cs1 +Cc1ccc(-c2nnn(CC(=O)N(C)c3ccccc3)n2)cc1 +CCc1cccc2c(CC(=O)Nc3c(C)n[nH]c3C)c[nH]c12 +COc1c(C)cnc(CNC(=O)c2cc(-c3cccnc3)on2)c1C +Cc1noc(C)c1C(C)NC(=O)N1CCCN(CC(F)(F)F)CC1 +Nc1ccc(Sc2nnc3n2CCCCC3)c(Cl)c1 +Cc1ccc(C(=O)NCc2ccc(-c3nc(C(C)C)no3)s2)s1 +O=C(Nc1ccc(C(=O)N2CCCC2c2cccs2)s1)C1CC1 +COC(=O)N(C)CC(=O)Nc1ccc2[nH]c(C)nc2c1 +O=C(c1ccco1)N1CCN(Cc2ccccc2)c2ncccc21 +CC(C)(C)C(=O)Nc1ccc(OCC2CCCO2)cc1 +O=S(=O)(CCCc1nc2ccccc2o1)c1ccccc1 +COc1ccccc1N1CCN(S(=O)(=O)C(C)C)CC1 +COC(C(=O)Nc1ccccc1-n1ccnn1)c1ccccc1 +C#CCN1CCN(C(=O)C(C)Oc2ccc(SC)cc2)CC1 +COc1ccccc1-n1ccn(Cc2ccccc2)c(=O)c1=O +CCn1cc(Nc2nc(C3CC3)nc3c(C)nn(C)c23)cn1 +O=C(NCC1CCCO1)NC1CCN(c2ccccc2)C1 +O=C(NCc1ccco1)NCc1nc(C2CCCC2)no1 +CSc1ccc(CNS(=O)(=O)N2CCCC(C)C2)cc1 +Cn1c(-c2ccc(Cl)cc2)nnc1S(=O)(=O)Cc1ccon1 +Cc1cccc2c(CCNC(=O)NCc3nnnn3C3CC3)c[nH]c12 +CC(C)Oc1ccc(NC(=O)Cc2cccc(OCC#N)c2)cc1C#N +Nc1c(Oc2ccc(F)cc2F)ncnc1N1CCCC1 +CNc1nc(-c2ccc(S(C)(=O)=O)cc2)nc2c1CCC2 +CC(Sc1nccn1C)C(=O)Nc1cccc2ncccc12 +Cc1cnc(N2CCc3ncnc(-c4ccc(F)cc4)c3CC2)nc1 +COCC(=O)OCC(=O)Nc1cc(Cl)cc(Cl)c1 +COC(=O)c1ccoc1CSc1nc(C)c(C)o1 +Cc1csc(C(C#N)C(=O)c2ccc(Cn3ccccc3=O)o2)n1 +NS(=O)(=O)c1cccc(O)c1S(N)(=O)=O +CN(Cc1cscn1)C(=O)c1nc(N)ccc1Cl +CC(C)N1CC(C(=O)NCCc2nncn2C)CC1=O +CCOC(=O)c1ccc(NC(=O)CCn2nnc3ccccc32)cc1 +CCNC(=O)c1cccc(CNC(=O)c2cccc(N(C)C)c2)c1 +Cc1ccc(CNC(=O)c2cc(NC(=O)C3CCCC3)n(C)n2)cc1 +CCCc1cc(O)nc(SC(C)C(=O)Nc2ccnn2C(C)C)n1 +COC(C)(C)c1noc(-c2csc(-c3ccc4c(c3)OCO4)n2)n1 +O=C(CCn1ncc2ccccc21)Nc1ccc(Cl)cc1 +CC(NC(=O)c1cc(F)c(F)cc1Cl)c1cnn(C)c1 +CN(C(=O)Cn1nnc(-c2ccco2)n1)C1CCCCC1 +CCc1onc(C)c1NC(=O)N(C)CC1CCC(C)CC1 +Cc1ccc(-c2nc(C(=O)N3CCNC(=O)C3)cs2)o1 +O=C(Nc1cnn(C2CCOCC2)c1)c1ccc2[nH]ccc2c1 +C=C1CCN(C(=O)c2csc(-c3cccs3)n2)CC1 +Cc1nc(CNC(=O)c2cc(Cl)ccn2)c(C)s1 +COCCC1CCCN(C(=O)c2ccc(CCC(C)(C)O)cc2)C1 +O=C(Nc1ccc(N2CCNC2=O)cc1)C1CC1(Cl)Cl +CCCn1cc(C(=O)OCC)c(=O)c2c(N)cccc21 +Cc1c(NC(=O)Cn2cnnn2)cccc1C(=O)Nc1nccs1 +CC(NC(=O)COc1ccccc1)c1noc(Cc2ccccc2)n1 +Cc1ncsc1C(=O)Nc1ccccc1C(=O)C(C)C +CCc1cnccc1C(=O)OCc1ccnc(-n2ccnc2)c1 +CCCc1nnc(SCC(=O)Nc2ccc(Cl)cc2)o1 +C=CCn1c(NCCCO)nc2c1c(=O)[nH]c(=O)n2C +CC(=O)Nc1nc(-c2ccccc2Cl)ns1 +c1ccc(CN(Cc2ccncc2)Cc2ccc3ccccc3n2)cc1 +COc1ccc(C)cc1N1CCN(C(=O)C2CCCC2)C(C)C1=O +Cc1cc(=O)[nH]c(SCC(=O)Nc2ccccn2)n1 +O=C(Nc1nc(C2CC2)cs1)c1c[nH]nc1-c1ccccc1 +Cc1cnc(C(=O)OCC(=O)Nc2ccc(F)cc2F)cn1 +CC(C)(C)C(=O)Nc1ccc(Oc2cccnc2)nc1 +O=c1cc[nH]c(C2NCCc3cc(F)cc(Cl)c32)c1 +CCc1cccc(C)c1NC(=O)CCCn1cncn1 +COC(=O)c1nnsc1NC(=O)CCc1ccc(OC)cc1 +CC(C)(O)C#Cc1ccc(C(=O)NCCc2[nH]nc3c2CCCC3)o1 +CCC(C)NC(=O)C(C)NCc1ccc(Cl)cc1Cl +COc1ccc(CCCNc2ccc(S(N)(=O)=O)cc2)cc1O +CCCN(Cc1ccsc1)S(=O)(=O)Cc1ccc(F)cc1 +CC(=O)c1ccc(OC(C)C(=O)Nc2ccc(F)c(F)c2F)cc1 +NS(=O)(=O)c1ccc(O)c(S(N)(=O)=O)c1 +CCOc1ccccc1OCC(=O)Nc1ccc(C(=O)NC)cc1 +CCCNC(=O)Cn1nnc(CO)c1C(Cl)(Cl)Cl +CC(C)(C)CNC(=O)c1[nH]cnc1C(=O)N1CCC(O)C1 +Nc1cc(F)cc2c1OC(c1ccccc1Cl)CC2=O +COc1ccc(C)cc1NC(=O)CCC(=O)c1cc(C)sc1C +Cc1cc(-c2csc(CC#N)n2)c(C)n1Cc1ccco1 +O=C(NCCCNC1=NS(=O)(=O)c2ccccc21)c1cccnc1 +CCOC(=O)c1ccc(N(C)CC(=O)NC2CC2)nc1 +CN(C)C(=O)C1CCC(CNc2ccc(C(F)(F)F)c(C#N)c2)O1 +CCc1ccc(C2CCCN2C(=O)Cc2ccc(NC(C)=O)cc2)o1 +COc1ccc(C(=O)CCC(=O)N(C)C)cc1C(C)(C)C +N#Cc1csc(CN2CCCN(Cc3cscn3)CC2)c1 +COc1ccccc1OS(=O)(=O)c1ccccc1Br +CCCCn1nnnc1CN1CCc2nn(CC)c(=O)cc2C1 +CCC(=O)Nc1ccc(NC(C)C(=O)NCc2cccs2)cc1 +Cc1noc(-c2cccs2)c1C(=O)NC(C)c1ccccc1 +Cn1c(N)c(C(=O)CN2CCN(CCO)CC2)c(=O)n(C)c1=O +CCCCc1nc(Cn2c(=O)c(C#N)cn(CC)c2=O)no1 +CC(C)(O)CN1CCN(C(=O)CCn2cc[nH]c(=O)c2=O)CC1 +CC(Sc1nc2ccccc2[nH]1)C(=O)N1CCOCC1 +CN(Cc1ccc(O)cc1)C(=O)Nc1nc2ccccc2s1 +N#Cc1ccsc1NC(=O)c1ccc(-n2ccnn2)cc1 +O=C(NCC1CN2CCCCC2CO1)c1n[nH]c(=O)c2ccccc12 +CCOc1ccccc1C(=O)Nc1cc(S(N)(=O)=O)ccc1C +Cc1cnn(C2CCCN(C(=O)Cn3ccc(C(F)(F)F)n3)C2)c1 +CC(C)NC(=O)NCCn1nc(C(F)(F)F)n(C)c1=O +O=C(NCC1(O)CCOCC1)Nc1ccc(C(F)(F)F)cc1 +CC1(C)Cc2cccc(OCC(=O)Nc3nncs3)c2O1 +Cc1cc(N(C)S(=O)(=O)c2cccs2)ccc1N +COc1ccc(Cl)cc1C(=O)Nc1cnn(C)c1 +CC(c1ccco1)N(C)C(=O)CNC1=NS(=O)(=O)c2ccccc21 +CC1CN(S(=O)(=O)CCNC(=O)c2ccc[nH]c2=O)CC(C)O1 +COCCOc1ccccc1NC(=O)c1cnc2[nH]nc(C)c2c1 +CCc1nc2n(n1)CCCC2NC(=O)NC1(c2cccc(F)c2)CC1 +CC(C)CCC(=O)N1CCC(c2nc3ccccc3[nH]2)CC1 +CCC1CN(C(=O)NCc2cnn(C)c2)CCO1 +COc1ccc2c(C)cc3nnc(SCc4nnc(C)o4)n3c2c1 +CCN(C(=O)c1cccc(F)c1N)C(C)COC +COc1cc(C(=O)NCC2(C(N)=O)CCCC2)ccc1OC(F)F +Cc1c(C(=O)NC(C)CN2CCOCC2)[nH]c2c1C(=O)CC(C)(C)C2 +Cc1c(C(=O)NCC(=O)N2CCCCC2)cn2nc[nH]c(=O)c12 +CSc1ccc(CN(C)C(=O)c2cc(C)no2)cc1 +O=C(C1CCC1)N1CCC(O)(c2cccnc2)CC1 +COc1cccc(N2CCN(c3nc(C)cc(=O)[nH]3)CC2)c1 +COCC(C)OC(=O)C(C)Oc1ccccc1Cl +Nc1c(C(=O)c2ccccc2)oc2c(O)cccc12 +Fc1ccccc1-c1cc(NCc2ccco2)nc(-c2ccncc2)n1 +Cc1nccc(C2CN(c3cnccn3)CCO2)n1 +CCCNC(=O)c1cc(S(=O)(=O)N(C)C(C)C)ccc1Cl +CCNC(=O)c1ccc(CNC(=O)CSc2ccccc2)cc1 +CCOC(=O)c1nnc2cc(-c3cccs3)sc2n1 +COc1ccc(CNC(=O)c2cccc(OC)c2F)cc1NC(C)=O +COc1ccc(OC)c(-n2cnc3c2N=C(O)CC3c2ccccc2)c1 +CCCCC(=O)N=c1sc2cc(S(C)(=O)=O)ccc2n1C +CC(C)(C)c1nnnn1CC(=O)N1CCCC1c1ccsc1 +Cc1ccccc1CNC(=O)N1CCN(Cc2cccnc2)CC1 +CN(C)c1ccc(Cl)cc1NC(=O)c1ccnc(F)c1 +CCOC(=O)c1csc(=NC(=O)c2ccccc2-n2cnnn2)[nH]1 +Cc1nc(C)c(CCNC(=O)N(C2CC2)C(C)c2ccco2)s1 +CCc1cc2c(N(C)Cc3cnn(C)c3)ncnc2s1 +O=C(c1ccc(COc2cccc3cccnc23)cc1)N1CCCC1 +Cc1ccc(N(CC(=O)NCc2cccnc2)S(C)(=O)=O)c(C)c1 +Fc1ccccc1C1CCN(Cc2nc(-c3cccs3)no2)C1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)NCCN1CCOCC1 +O=C(NCC(c1ccc(Cl)cc1)n1cccn1)c1csnn1 +O=C(CC(F)(F)F)NCc1cccnc1-n1cncn1 +O=C(Nc1nc(-c2c[nH]c3ccccc23)cs1)c1ccc(=O)[nH]c1 +N#CCc1ccccc1C(=O)OCC(=O)NCc1cccs1 +CCCc1cc(C(=O)OC)c(NC(=O)c2ccc(C)o2)s1 +Cc1cc2n(n1)CCCN2C(=O)CCC(=O)Nc1ccc(F)cc1 +Cc1cc(NCCc2ccc(Cl)cc2)cn2nc(N)nc12 +CC(C)c1nc2cc(N)ccc2n1CC1CCCC1 +Cc1cc(C(=O)C2CCCCN2)ccc1OC(C)C +CC(NC(=O)CCC1Cc2ccccc2NC1=O)c1cccnc1 +CC(C(=O)N1CCCC(n2cccn2)C1)n1c(=O)oc2ccccc21 +COCCNC(=O)N1CCN(CC(O)C2CC2)CC1 +OC1(CC#Cc2ccccc2)c2ccccc2C12OCCO2 +COc1ccc(CN(C(=O)C2OCCC2C)c2nccs2)cc1 +O=C(Cc1cccc(Cl)c1)Nc1ccc2c(c1)OCO2 +CC(C)c1ccc(C#N)c(=O)n1CCN1CCOCC1 +CCN(C(=O)C1COc2ccccc21)c1ccc(OC)nc1 +COCC(C)NC(=O)CSc1nnc(-c2cccs2)n1N +CSc1ncccc1C(=O)Nc1ccc2c(c1)OCCO2 +CCN(C(=O)NC1CCN(CC(F)(F)F)C1)C(C)C(C)C +CC(C)CCNC(=O)c1cc(-c2ccc(F)cc2)n[nH]1 +O=S(=O)(NCc1ccc(Cl)cc1)c1ccc2c(c1)OCCO2 +CCNC(=O)CN1CCN(C(=O)c2ccc(C(C)C)cc2)CC1 +COc1cc(-c2nncc(N)n2)cc(OC)c1OC +Cc1ccc(N2CCC(NC(=O)NC(C)CCCO)C2=O)cc1 +O=C(Nc1cnc(-c2ccccc2)nc1)c1cc(F)cc2[nH]cnc12 +COC(=O)c1cc(Br)ccc1NC(=O)N1CCCC1 +CCc1oc(C(=O)OC2CCN(C(C)=O)C2)cc1C +O=C(CNc1ccc(C(=O)N2CCCC2)cc1)NCC1CCCCC1 +CC(Oc1ccc(Cl)cc1Cl)C(=O)NCc1ccncc1 +Cc1ccc(F)c(NC(=O)CSc2nnnn2-c2ccccc2)c1 +N#Cc1ccc(OCCCSc2nncs2)cc1 +Cc1nn(-c2nc3ccccc3o2)c2c1C(c1ccccc1)CC(=O)N2 +CC(=O)c1c(SCC(=O)NCC(F)(F)F)nc(=O)[nH]c1C +O=C(NCc1ccc2c(c1)OCO2)C1CC=CCC1 +Cc1c(NCC(=O)N2CCc3sccc3C2)cccc1C(N)=O +CN1C(=O)c2ccccc2NC1c1cccc2cccnc12 +N#Cc1ccnc(N2CCN(S(=O)(=O)c3ccccc3F)CC2)c1 +Cc1n[nH]cc1CNCCc1ccccc1C(F)(F)F +CCOCCCn1c(C2CCCO2)nc2ccc(Cl)cc21 +Cn1cnc2cc(C(=O)N3CCCCC3CCO)ccc21 +COCCC1(CNC(=O)C2COc3ccc(F)cc3C2)CCC1 +Cc1ccc(Cl)cc1NCC(=O)NCC1CC1 +COc1cc(C(C)NC(C)=O)cc(OC)c1OC +Cc1cc(NC(=O)CN2CCCS2(=O)=O)n(C(C)(C)C)n1 +C#CCNC(=O)c1ccccc1NC(=O)C1CCCC1 +CC(C)n1nccc1NC(=O)N1CCN(C(=O)c2ccco2)CC1 +COc1ccccc1N1CCN(C(=O)Nc2ccccc2)CC1=O +O=C(Nc1cccnc1)N(CCC(F)(F)F)CC(O)CO +O=C1CCCc2[nH]c(=O)c(C(=O)OCCOCC(F)(F)F)cc21 +Cc1ccc2ncc(C(=O)OCc3cn4ccccc4n3)n2c1 +Cc1cnc(C(=O)N2CCC(C(=O)N3CCCCC3)CC2)cn1 +COCCN(Cc1ccc(F)cc1)S(=O)(=O)c1ccc(C#N)cc1 +O=C1NCC(=O)N2CCN(C(=O)NCc3ccco3)CC12 +CC(C)(O)c1cn(C2CCN(C(=O)C3CC34CCCCC4)CC2)nn1 +CC1=NC(=O)C(CC(=O)NCCOc2cccc(Cl)c2)C(C)=N1 +COCc1ccc(CNC(=O)c2cc(F)c(F)c(F)c2F)cc1 +CC(=O)N1CCCN(C(=O)c2ccccc2C(F)(F)F)CC1 +CC1CN(C)c2ccccc2CN1c1cc(-n2ccnc2)ncn1 +CN(CCC#N)C(=O)Nc1ccc(OCc2cccc(F)c2)c(F)c1 +COCCN(Cc1ccco1)S(=O)(=O)c1cccc(Cl)c1 +CCc1nc(CC(=O)N(C)c2cc(Cl)ccc2C#N)cs1 +CCCNC(=O)Cc1noc2c(N)cc(CC)cc12 +COc1cc(C)c(Cl)c(C)c1-c1cc(N)ncn1 +O=C(NCc1cscn1)Nc1cccc(N2CCNC2=O)c1 +O=C(COc1ccc[nH]c1=O)N1CCCCCC1 +N#CC1(NC(=O)Cn2nnc3ccccc32)CCC1 +CNC(=O)C(C)N(c1ccc(OC)c(OC)c1)S(C)(=O)=O +CCN(Cc1cnc(-c2ccccc2C)s1)C1COCC1O +Cc1c(C(=O)NCCNC(=O)OC(C)(C)C)oc2c1C(=O)CCC2 +NC(=O)c1cccc(CNC(=O)c2cc(Br)ccc2O)c1 +Cc1cc(NC(=O)Cc2ccc3c(c2)c2ccccc2n3C)[nH]n1 +CC(=O)N1CCC(C(=O)OCCc2cccc(Cl)c2)CC1 +CN(C)c1ncccc1C(=O)Nc1cc(Cl)cc(Cl)c1 +CCOc1nc(CC)nc(NCCN2CCOCC2)c1N +c1cc(CSc2nnc(N3CCCC3)s2)c2c(c1)OCCO2 +CC1(C)C(=O)Nc2ccc(S(=O)(=O)N3CCc4ccccc43)cc21 +O=C(Cn1c2ccccc2c(=O)c2ccccc21)OCC1CCCO1 +COCCNc1nc(NCc2cccc(C)c2)c2cnn(C)c2n1 +COc1ccc(OCc2noc(CN3CCOC(C)C3)n2)cc1 +O=c1c2ccccc2cnn1CCCS(=O)(=O)c1ccccc1 +N#Cc1ncn(CC(=O)N2CCN(Cc3ccccc3)CC2)n1 +Cc1ccc(NC(=O)NC(C)c2cnn(C)c2C)cc1 +CCn1cc(CN(C)C(=O)c2cccc(CCC(C)(C)O)c2)cn1 +C=CCn1c(C)nnc1SCc1nc2cc(F)ccc2n1CC +COc1cccc(-c2noc(C(F)(F)c3ccccn3)n2)c1 +CCCn1ccc(NCc2cc(F)ccc2F)n1 +CC(C)(C)OC(=O)C1(c2cccc(Br)c2)COC1N +Cc1ccc(NC(=O)C(C)c2c(C)noc2C)cc1S(C)(=O)=O +COCC(C)N1CCN(C(=O)c2cc(=O)c3ccccc3o2)CC1 +Cc1ccc2[nH]nc(-c3nc(-c4ccc(C#N)cn4)no3)c2c1 +CCn1nc(C)cc1C(=O)Nc1ccc(S(C)=O)cc1 +Cc1ccc(-c2nc(CC(=O)N3CCNC(=O)C3)cs2)cc1 +CN(CCC#N)C(=O)Cc1coc(-c2ccc(Cl)cc2)n1 +CCCC(=O)Nc1nnc(-c2ccc(C)cc2C)o1 +O=C(NCc1ccnc(OC2CCC2)c1)C1Cc2cc(F)ccc2O1 +O=C(Cc1cccc(F)c1)NC1CCN(c2ccccc2)C1=O +CCCc1cc(C(=O)NCC2CCCO2)sc1C +Cc1ccc(CN(C(=O)NCc2ccnn2C)C2CC2)cc1C +CCN(Cc1cccc(F)c1)C(=O)NCCC(=O)NC(C)C +COc1ccc2c(cnn2Cc2ccc(C#N)cc2)c1 +Cn1cc(Br)cc(NC(=O)NC(CCO)C2CC2)c1=O +CNC(=O)C(NC)c1ccc(OC)c(NC(C)=O)c1 +Cc1oc(C)c(C(=O)NCCc2ccc(O)cc2)c1C +O=C(c1cscn1)N1CCC2C1CCN2c1ncc(F)cn1 +CN(Cc1cccc(F)c1)C(=O)NCc1cscn1 +O=C(CN1CCOC(CNc2cccnn2)C1)NCC1CC1 +Cc1cc(C(=O)N(C)CC(=O)Nc2ccccc2)c(C)n1C1CC1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)Nc1ccc(Cl)cn1)O2 +CC1CC(Sc2nc3sc4c(c3c(=O)n2C)CCC4)C(=O)O1 +CCNc1nc(-c2cc(C(C)C)oc2COC)cs1 +Cc1sc(NC(=O)Cn2cccnc2=O)nc1-c1ccc(F)cc1 +NC(=O)C(Nc1ncnc2c1oc1ccccc12)C1CCOC1 +Cc1ccc(C(=O)NCc2cc(=O)oc3ccc(F)cc23)cc1 +CCN(C(=O)COC(=O)c1nccnc1N)C1CCCCC1 +Cc1c(N)cc(C(=O)NC2CCCCC2C)cc1F +COc1cccc(CNC(=O)c2cc(OC)c(C)c(OC)c2)c1 +COCC1CCN(C(=O)c2cc(S(C)(=O)=O)ccc2Cl)CC1 +CC(=O)Nc1cccc(CNC(=O)N2CCOC(C)(C)C2)c1 +Cc1ccc(NC(=O)CCNC(=O)Nc2cnccc2C)c(Cl)c1 +Cc1ccc(F)c2c1CCNC2c1ccc(N)cc1 +CCC(CC#N)NC(=O)c1cc2ccccc2s1 +Cc1csc(Cn2ccc(-c3ccsc3)n2)n1 +O=C(Nc1ccc(OC(=O)C2CC3CCC2O3)cc1)c1ccccc1 +Cc1ccc(C)c(OCC(O)Cn2cnc3sccc3c2=O)c1C +N#Cc1cccc(NC(=O)CCc2ccccc2N)c1 +O=C(NCc1ccccn1)c1ccc(O)c(Cl)c1 +COc1ccc(CNC(=O)CSc2nncn2C(C)C)cn1 +COc1cc(C(=O)Nc2nccs2)ccc1OC(C)=O +CCN(CCOc1ccccc1C)C(=O)C1N=C(C)C=C1C +O=C1CCN(C(=O)c2c(Cl)cccc2Cl)CC1 +CC1CCCC(NC(=O)c2cccc(C(N)=O)c2)C1C +CCOc1c(OC)cc(C=Cc2ncc(C(=O)NC)s2)cc1OC +O=C(NCC1CCCO1)c1ccc(-n2cccn2)nn1 +CCN(CC(=O)Nc1nc2ccc(F)cc2s1)CC(C)C#N +Cc1ccc(F)cc1NC(=O)Cn1nc(C(F)(F)F)cc1C +CC(=O)N1CCc2cc(S(=O)(=O)NC3CCCCC3C)ccc21 +CCN(Cc1ccc2c(c1)OCO2)C(=O)C(C)(C)C#N +CCCn1c(C(=O)NCCCCO)cc2c(=O)n(C)c(=O)n(C)c21 +CCc1ccccc1-n1cnnc1SCC(=O)NCC(C)O +O=S(=O)(c1cccnc1)N1CCn2c(nnc2-c2ccccc2)C1 +CCN(C(=O)c1cc(C)n(Cc2ccccn2)c1C)c1ccccc1 +COc1cccc(NC(=O)COC(=O)c2cccc(OC)c2)c1 +COc1ccc(OC)c(C2(C(C)=O)CCCCC2)c1 +Cc1ccc(C(=O)NCC(=O)Nc2c[nH]nc2C)cc1 +COC(=O)Nc1ccc(NC(=O)Nc2ccccc2)cc1 +Cc1csc(NC(=O)NCc2ccc(F)cc2C(F)(F)F)n1 +O=C(Nc1ccccc1C(=O)N1CCCCCC1)c1ccco1 +CCc1cccc2c1N(C(=O)c1cccc(C)n1)CCC2 +CCOC(=O)c1nsc(C(=O)Nc2cccnc2)c1N +Cc1ccc(NC(=O)c2ccc(F)c(S(N)(=O)=O)c2)cc1 +Cc1ccsc1C(=O)N1CC2CC(NS(C)(=O)=O)C1C2 +CCc1cccc(CC)c1NC(=O)CN1CCN(C(=O)C2CC2)CC1 +Cc1noc(C)c1CC(=O)N1CCCC1C(=O)Nc1ccccc1 +O=C(Cc1nc(CO)cs1)Nc1ccc(F)c(Cl)c1 +CCCC(C)NC(=O)Nc1cc(C(=O)NC2CC2)ccc1C +O=C(NCC(F)(F)F)Nc1cccc(Br)c1 +COC(=O)CNC(=O)C(C)Sc1nc2ccccc2s1 +OCc1cc(-c2ccc(C(Cl)(Cl)Cl)cc2)no1 +COc1ccccc1CC(=O)Nc1ccc(NC(=O)NC(C)C)cc1 +CCc1cccc(OCC(=O)NCc2ccc(S(N)(=O)=O)cc2)c1 +Cc1nc(C)c(CC(=O)N2CCCC2c2ccc(C)c(C)c2)c(=O)[nH]1 +CCC(C)n1ncc(C(=O)NC2CCc3nc(C)nn3C2)c1C1CC1 +CCn1nc(C)cc1NC(=O)COc1ccccc1Cl +Nc1nccnc1C(=O)Nc1cccc(-c2nnc3n2CCCCC3)c1 +CCCCCn1cnc2sc3c(c2c1=O)CCC3 +O=c1[nH]c(CNc2cccc(Cl)c2)nn1Cc1ccc(F)cc1 +Cc1nc2ccc(NC(=O)C3CCN(C(=O)C(C)C)CC3)cc2o1 +CC(C)N(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccc(F)cc1 +Cc1ccc(N2CCC(=O)C(C)C2)c(Br)c1 +Cc1cc(C(C)C)nc(CCc2ccccc2N)n1 +CCCS(=O)(=O)NC1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +CC(C)(C)C(=O)CSc1nc(-c2ccccc2)c[nH]1 +Cc1ccc(CNC(=O)c2cc(S(N)(=O)=O)oc2C)c(C)c1 +CCCCn1nnc(S(=O)(=O)c2ccccc2)c1N +Cc1ccc(C(=O)NCC(=O)N2CCC(C3OCCO3)CC2)cc1C +COc1cccc(C(=O)NCCC(=O)Nc2nnc(C(C)C)s2)c1 +O=C(Nc1n[nH]c(C2CC2)n1)c1ccc2nnnn2c1 +CCn1nc(C(=O)N2CCN(c3ccccc3OC)CC2)ccc1=O +O=C(Cn1cccn1)NCC#CCOc1cccnc1 +COC(=O)C1(NCC(F)(F)F)COc2cc(O)ccc21 +N#Cc1ccccc1OCC(=O)Nc1ccccc1 +CC(C)(C)c1nc(CNc2ccc(CN3CCOC3=O)cc2)cs1 +CCn1ncc(CN(C)C(=O)CC23CC4CC(CC(C4)C2)C3)c1C +CCOC(=O)c1oc2ccccc2c1CSc1ncn[nH]1 +CCC(=O)NCC(O)c1cc(OC)ccc1OC +O=C(CCN1CCOC1=O)NCc1ccccc1F +Fc1ccc(NCc2cc(CN3CCOCC3)cs2)cc1 +O=C(CCc1cccnc1)N1CCOC(Cc2cccc(F)c2)C1 +CC(C)c1ccc(C2CC2C(=O)N(C)CC(O)CO)cc1 +O=C(NCc1cccc(CN2CCOCC2)c1)C1CCOCC1 +CCC(C)(C)C(=O)N(C)c1ccc(S(N)(=O)=O)cc1 +CC(C)(C)C(=O)Nc1ccc(CC(=O)NCC(F)(F)F)cc1 +Cc1nnn2c1COCC(CNC(=O)NCc1cccc(F)c1)C2 +CC(C)NS(=O)(=O)c1cccc(C(=O)N2CCc3ccccc32)c1 +CC(Cn1cncn1)NC(=O)Cn1ccc(=O)n(C)c1=O +COc1ccc(CN(C)C(=O)c2c(C)cc(C)[nH]c2=O)cc1 +CCCn1cc(NCc2cc(C#N)n(C)c2C)cn1 +CC(C)c1cccc(CSc2nnc(Cn3cncn3)o2)n1 +CC(C)N(C)c1cccc(NC(=O)NCc2ncn(C)n2)c1 +NC(=O)CCN(C(=O)c1ccc(F)cc1F)c1ccc(F)cc1 +CCN(CC)C(=O)c1cc(S(=O)(=O)N2CCCCC2)c[nH]1 +CC(OCC(F)(F)F)C(=O)N(C)Cc1ccc(O)cc1 +Cn1ccc2ccc(NC(=O)c3ccn4nnnc4c3)cc21 +CC(=O)NCCNC(C)C(=O)c1ccc2c(c1)CCCN2 +CCCOc1ccc(NC(=O)NCc2cccnc2)c(C)c1 +COc1ccccc1NC(=O)CSc1nnc2nc(C)cc(C)n12 +Cc1csc(NC(=O)c2cc(C)n(C3CC3)c2C)n1 +CC(=O)C1C(c2cccc(C)c2)NC(=O)NC1(O)C(F)(F)F +COC(=O)C1=C(N)Oc2c(oc(CO)cc2=O)C1c1ccc(F)cc1 +CC(NC(=O)c1ccc(=O)[nH]c1)C12CC3CC(CC(C3)C1)C2 +CC(NC(N)=O)C(=O)N1CCCc2cc(C(C)(C)C)ccc21 +CCn1cc(NC(=O)c2cccc(-c3noc(C4CC4)n3)c2)cn1 +CC(=O)c1nccn1-c1ccc(C(F)(F)F)cc1 +COc1cc(NC(=O)COC(=O)c2ccc(F)cc2N)cc(OC)c1 +Cc1cccc(C(=O)N(Cc2cc3ccccc3[nH]c2=O)C(C)(C)C)c1 +O=C(NCc1ccccc1Cl)c1nnc(-c2cccnc2)o1 +O=C(Nc1ccccc1)c1nnc(C(=O)N2CCCCCC2)s1 +CCC(C(=O)Nc1c(C)nc2ccccn2c1=O)c1ccccc1 +COc1ccc(C)cc1CCNC(=O)NCc1ncn(C)n1 +CCOc1ncc(C(=O)N(C)c2cccc3ncccc23)cc1Cl +O=C(NCc1ccc(OCC(F)(F)F)cc1)NCc1ccccn1 +COc1ccc(S(=O)(=O)N2CCCCC2)cc1OC +Cc1cccc(C2(NC(=O)NCc3nnc4n3CCC4)CCCC2)c1 +O=C(Nc1ccccc1)Nc1ccc(C(=O)N2CCOCC2)cc1 +O=C(c1ccsc1)N1CCC2(CC(Oc3cccnc3)CO2)C1 +CC(NC(=O)C(C)(C)C)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +CC(=O)NC(C)(C)c1noc(CCc2ccc(C)cc2)n1 +Cc1nc(CN(C)C(=O)CNC(=O)CC(C)(C)C)cs1 +Cc1ccccc1C(=O)NCC(=O)Nc1ccc(Cl)cc1 +O=C(c1coc(CN2CCOCC2)c1)N1CCCC1c1nccs1 +N#Cc1ccnc(SC(C(=O)N2CCCCC2)c2ccccc2)c1 +CNC(=O)NCC(=O)NC1CCN(c2cccc(Cl)c2)C1 +CCN(c1ccccc1)S(=O)(=O)c1cccc(C#N)c1 +O=C(c1cc(C2CC2)on1)N(Cc1ccco1)Cc1ccco1 +Cn1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cn1 +COc1ccc(Cn2c(C)csc2=O)cc1Br +Cc1nc(C(=O)NC2CCN(C(=O)C(C)C)CC2)cs1 +Cc1oc(C(=O)OC(C)c2cccnc2)cc1S(=O)(=O)N(C)C +COC(=O)c1ccc(NCc2cccnc2)c(O)c1 +N#Cc1ccc(NCc2nnc(-c3ccc(F)cc3)o2)cc1 +CCCC(=O)Nc1cccc(NC(=O)NCCO)c1 +O=C(Oc1ccc(N2CCOC2=O)cc1)c1ccsc1 +CC(C)Cn1nccc1NC(=O)Cc1ccc(-n2cnnn2)cc1 +Cc1noc(CCC(=O)NCCCc2cn[nH]c2C)n1 +CCOCC1CN(Cc2cnn(C)c2)Cc2c1cnn2CC +CC(=O)N1CCc2onc(-c3ccc(-c4ccccc4)cc3)c2C1 +CNS(=O)(=O)c1cc(C(=O)N2CC(C)CC(C)C2)cc(C)c1C +Cc1nc2ccc(C(=O)NCCNC(=O)c3cccnc3)cc2nc1C +Cn1cc(-c2ncc(C(=O)N(Cc3ccncc3)C3CC3)s2)cn1 +O=C(NCc1ccncc1)c1c[nH]c2c(Cl)cccc2c1=O +COc1cc(N)ccc1NC(=O)COc1ccc(F)cc1 +Cc1cc2c(c(C(O)c3ccccc3C)c1)NC(=O)C2C +COc1cc(OC)c(-c2cc(CO)c(C3CC3)o2)cc1OC +N#Cc1ncn(Cc2c(F)cccc2Br)c1C#N +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)Nc1nccs1)O2 +Cc1ccccc1C(=O)N1CCc2ccc(CNC(=O)C3CCC3)cc21 +CCOC(=O)N1CCN(C(=O)c2ccccc2-c2ccccc2)CC1 +CCc1nc2n(n1)C(CC(=O)Nc1cc(C)ccc1C)C(=O)N2 +O=C(Nc1ccnc2ccc(C(F)(F)F)cc12)c1ccncc1 +CC(NC(=O)N1CCCC1c1ccc2c(c1)OCCO2)C1CCCO1 +C=C(C)CN(C)S(=O)(=O)c1ccccc1Br +CC(C)Cc1ncc2c(n1)CN(C(=O)c1cnn3ccccc13)C2 +CCOc1cc(CNc2ncnc3sc4c(c23)CCC4)ccn1 +COCCNC(=O)c1c(N)n(N)c2nc3ccccc3nc12 +COc1ccc(Cn2c(=O)[nH]c3ccccc32)cc1 +COC(=O)C1=C(N)Oc2[nH]nc(C)c2C1c1ccc(C)cc1 +CC(C)Cn1nccc1NC(=O)c1ccc(OCC(F)F)nc1 +N#Cc1cccc(NC(=O)NCc2ccccc2-n2ccnc2)c1 +C=C(C)COc1ccc(C(=O)NCCOC)cc1N +COC(=O)c1c(-n2cccc2)c2cc(F)ccc2n1C +COc1ccccc1OCc1ccc(C(=O)N(C)C(C)C2CC2)o1 +COc1ncccc1C(=O)NCCN(C)C(=O)OC(C)(C)C +CCCNC(=O)CNC(=O)Nc1cc(-c2nnco2)ccc1C +Cc1cnn(CCC(=O)Nc2ccc(N3CCNC(=O)C3)nc2)c1 +Cc1cc(CC2COCC2NC(=O)Cc2ccc(F)cc2)on1 +CCn1c(C)cc(C(=O)NCC2CCN(c3ccccc3)C2)c1C +COc1cccc(NC(=O)c2c[nH]c3ccccc3c2=O)c1 +CCC(OC)C(=O)Nc1c(-c2ccc(F)cc2)nc2sccn12 +CNC(=O)CC(CC(C)C)c1cc(C)ccc1OC +Cc1ccc(COc2ccc(CNC(C)C(N)=O)cc2)cc1 +N#CC(C#N)C(C#N)c1ccc(Cl)c(Cl)c1 +Cc1ccc(F)cc1NC(=O)C1CCCN(c2ncccn2)C1 +Nc1nccnc1C(=O)N1CCN(Cc2ccncc2)CC1 +COc1cccc2c1OCC(NC(=O)CSc1ccc(F)cc1)C2 +O=C(NCCn1ncccc1=O)c1cccc2ccccc12 +O=C(NCc1ccc(F)c(Cl)c1)c1cn[nH]c1-c1ccccc1 +O=C(Nc1ccc2c(c1)OCCO2)N1CCCC1c1nccs1 +Cc1cc(F)c(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)cc1F +CC(C)(C)OC(=O)N1CCCC(NC(=O)N2CC3CCC2C3)C1 +O=C(Cn1ccc2ccc(Cl)cc21)Nc1cn[nH]c1 +Cc1cccc(C(=O)N2CCC(c3nc4ccccc4s3)CC2)c1 +O=C(NC1CC1)c1ccc(S(=O)(=O)NCc2cccnc2)cc1 +N#Cc1cccc(C(=O)Nc2cccnc2-n2cncn2)c1 +NC(=O)c1cccc(OS(=O)(=O)c2ccc3ccccc3c2)c1 +CC(C)(C)C(=O)NCCC1CCN(C(=O)c2ccc(F)cc2)CC1 +CCCCOc1cc(C)nc2cc(C3CCOCC3)nn12 +Cc1nc(CNC(=O)C2CCC(=O)N2)oc1-c1ccc(Cl)cc1 +CC(=O)c1cn(Cc2cc(-c3ccccc3)on2)nc1C +Cc1ccccc1N1CC2(CCN(C(=O)CC3CC3)C2)CC1=O +CCCNc1snnc1COCc1ccccc1 +N#Cc1cccc(C(=O)Nc2nc(C3=CN=C(C(N)=O)C3)cs2)c1 +CCn1nc(C)c2c1cnn2CCNC(=O)c1cc(C)no1 +CCC(C)N(C)C(=O)c1cnn(-c2ccncc2)c1C +CCOc1cc(C(=O)NCC(C)C)ccc1OC +Cc1csc(NC(=O)NC(C)Cc2ccccc2F)n1 +CC1CN(Cc2cccc(CNC(=O)N3CCCC(O)C3)c2)CCO1 +Nc1nc2n(n1)C(c1ccccc1)CC(c1ccc(Cl)cc1)N2 +Cc1nc(C2(NC(=O)c3cc(F)cc4[nH]cnc34)CCCCC2)no1 +CCC(C)NC(=O)CSc1nn(-c2ccccc2)c(=O)[nH]1 +Cc1ccoc1C(=O)N1CCN(c2ccc(O)cc2)CC1 +CC(C)CNC(=O)c1nc(-c2cccs2)cs1 +COc1cc(NC(=O)c2cc(-c3ccc(F)cc3)[nH]n2)cc(OC)c1 +O=C(c1c[nH]nc1-c1ccccc1)N1CCC(O)C1 +Cc1cccc(NC(=O)Cn2ccc(=O)c3cccc(F)c32)c1C +COc1cc(C(=O)OCC2CCCCO2)ccc1OC(C)C +CCc1ccc(Oc2ncnc(N3CCOCC3)c2N)cc1 +CC(C#N)N(C)C(=O)c1ccc(Br)cc1 +Cc1ccsc1C(=O)OCc1nc(N)nc(N(C)C)n1 +CCCn1nc(C(=O)OCC(=O)N2CCCCCC2)ccc1=O +Cc1ccc(C(=O)Nc2cc3c(cc2N)OCCO3)cc1 +CC(C)N1CC(C(=O)NCc2ccnc(OC3CCC3)c2)CC1=O +Nc1cc(F)c(SCCn2cccn2)c(F)c1 +O=C(CCSc1nnc2ccccn12)Nc1ccc(F)cc1 +Cc1nnc(N2CCC(C(=O)NCC(F)(F)F)CC2)c(C#N)c1C +O=C(Nc1ccn(Cc2ccccn2)n1)c1ccccc1OCC1CC1 +NC(=O)COc1ccccc1C(=O)Nc1ccc2c(c1)CCC2 +CCc1nc(CC)n(CC(=O)NCc2cccc(C)c2)n1 +CCn1cc(CNC(=O)Nc2cccc(OC)c2)cn1 +CC(C)(C)n1c(CC(F)(F)F)nc2cc(N)ccc21 +Cc1ccc(-n2ccnc2)c(C(=O)NCCCC(N)=O)c1 +COCC(C)n1c(CCCC(=O)N2CCOCC2)nc2cccnc21 +COC(=O)Nc1nc(CC(=O)N2CCc3ccccc32)cs1 +COC(=O)c1cc(C)nc(Nc2cccc(C(C)O)c2)n1 +CN1C(=O)CCc2cc(C(=O)C3CCCC3)ccc21 +COC(=O)C1=C(C)N(C)C(=O)NC1c1cccc(O)c1 +CC(NS(=O)(=O)c1ccc(Cl)c(N)c1)c1ccco1 +CN(Cc1ccc(Cl)cc1)C(=O)c1ccc(-n2ccnc2)nc1 +COC(=O)CN(C(=O)c1ccc(Br)cc1C)C(C)C +O=C(Nc1nc(-c2ccc[nH]2)cs1)C1CC(=O)N(C2CCCC2)C1 +CN1CCN(Cc2cnc(-c3ccsc3)s2)C(C)(C)C1=O +Cc1onc(-c2ccccc2)c1C(=O)N=c1sccn1C +Cc1cc(NC(=O)CN2c3ccccc3CC2C)on1 +CS(=O)(=O)NCCn1ncc2c(N3CCOCC3)ncnc21 +CCNC(=O)COc1ccc(NC(=O)N(C)CCC#N)cc1 +COCCOC(=O)c1cc2c(C)nn(-c3ccc(F)cc3)c2s1 +Cc1cccc(NC(=O)C2CC(O)CN2C(=O)OC(C)(C)C)c1 +C=CCc1c(O)nc(SCC(=O)NC(C)(C)C)[nH]c1=O +COc1ccc2c(c1)CC(C(=O)Nc1c(C)cc(C)cc1C)CO2 +Cc1nn(C)c(C)c1C(C)C(=O)N(CC1CCOC1)c1ccccc1 +CCc1ccc(OCC(=O)Nc2ccc(N3CCOCC3)nc2)cc1 +CC(C)(C)C(=O)NCC(=O)Nc1cc(Cl)c(N)c(Cl)c1 +CN(Cc1ccsc1)C(=O)CSc1ccccn1 +CC(=O)c1sc(C2CCCO2)nc1C(C)(C)C +Cc1ccc(Oc2ncnc(N3CCCCC3)c2N)cc1C +COc1ccc(OCCN(C)S(=O)(=O)c2ccc(F)cc2)cc1 +CCCOCC(=O)Nc1ccc(C(=O)NC2CCCCC2)cc1 +Cc1cc(CN2CCN(C(=O)c3cccc(O)c3)CC2)ccc1F +CSc1nccn1-c1cccc(C(=O)Nc2ccnc(C)c2)c1 +CC(Oc1ccc(C#N)cc1)C(=O)N(C)Cc1ccccc1F +CCN(CC1CCOC1)C(=O)CCC(=O)N1CCOc2ccccc21 +CCCC(C)(NC(=O)c1ncn(-c2ccccc2)n1)C(=O)OC +Cc1cccc2[nH]c(CCC(=O)OCCC(F)(F)F)nc12 +CCn1cc(NC(=O)NCc2ccc(OC)c(O)c2)cn1 +CCn1c(N)nc2cc(C(=O)N3CC4C5CCC(O5)C4C3)cnc21 +Cc1nc(C)c(C(=O)Nc2nnc(C3CC3)s2)s1 +CS(=O)(=O)c1ccc(OCCn2nccc2-c2ccncc2)cc1 +COc1ccc2c(c1)CCCC2CC(=O)OCCN1CCCC1=O +CC(C)(C)OC(=O)N1CCN(C(=O)c2cc(Cl)ccc2F)CC1 +O=C(Nc1nc[nH]n1)c1cc(-n2cccc2)ccc1Cl +CC(=O)c1cccc(OCc2noc(-c3cccs3)n2)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1ccnc(SC)c1 +Cc1nc(C)n(Cc2ccc(F)c3cccnc23)n1 +O=C(NCCc1cccnc1)C1(c2ccc(Cl)cc2)CCC1 +CNC(=O)Cc1ccc(NS(=O)(=O)Cc2cccc(C)c2)cc1 +COc1ccc2nc(NC(=O)C(C)c3ccsc3)sc2c1 +Cc1ccccc1CN(C)C(=O)C1CC2CCC1O2 +Cc1noc(CNCc2csc(-c3ccc(F)cc3)n2)n1 +O=C(Nc1ccccc1)N1CCCC1c1ccccn1 +CCOc1cccc(CNC(=O)Cc2c(C)noc2C)c1 +COc1cc(Cl)ccc1C(=O)N1CCCN(S(C)(=O)=O)CC1 +CN(C)C(=O)CNC(=O)c1c(O)cc(F)cc1F +Cn1nc(C(=O)NC(C)(C)CC(C)(C)C)ccc1=O +Cc1cc(C)cc(NC(=O)CNc2cc(-n3cnnn3)ccc2F)c1 +COC(=O)C1CCC(CNC(=O)OC(C)(C)C)O1 +Cc1ccc(-n2nnnc2NCc2cccc(Cn3cncn3)c2)cc1 +CN(C)C(=O)c1cccc(CCNc2cnn(C)c(=O)c2Cl)c1 +CC1CCN(C(=O)CSc2nnc(N)n2C2CC2)CC1 +Cc1cc(CCNC(=O)c2ccc(OC(C)C)cc2)on1 +CN(CC(O)C1CC1)C(=O)CSc1nnnn1C1CC1 +Cc1noc(C(C)C)c1C(=O)Nc1nccs1 +O=C(Cn1ccccc1=O)NC1(c2ccc(Cl)c(Cl)c2)CC1 +CCNc1cccc(-n2nnnc2C(N)=O)c1C#N +COc1c(C)cc(Cl)cc1-c1cc(=O)[nH]c(=O)[nH]1 +O=C1CN(C(=O)NCCCc2ccccc2)CCN1 +Cc1ccc2c(c1)N(C(=O)c1cccnc1)CCC2 +CC1CN(CCNC(=O)c2csc(-c3ccco3)n2)CC(C)O1 +COCCN1CCN(S(=O)(=O)c2cccc3cc(C)cnc23)CC1 +CNS(=O)(=O)c1cc(C(=O)NCc2ccco2)ccc1Cl +Cc1ccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3)cc1 +COc1ccnc(NC(=O)c2cn(CC(=O)C(C)(C)C)nn2)c1 +Cc1cc(C)nc(-n2nc(C)c(CC(=O)N3CCCC3(C)C)c2C)n1 +COC(=O)N1CCCC(C(=O)OC(C)c2ccccn2)C1 +CCCOc1ccc(C(=O)Nc2nnn(CCC)n2)cc1 +CCN(CC)C(=O)c1ccc(Cl)c(NC(=O)C2(C)CCCO2)c1 +Fc1cncc(C2NCCc3cc(C(F)(F)F)ccc32)c1 +O=C(Nc1ccccc1)c1cc2cc(F)ccc2[nH]1 +COc1ccccc1CCNCc1cn(C)nc1C +COc1cc(C(C)=O)ccc1OCC(=O)Nc1cc(C)on1 +CN(Cc1ccc(Cl)cc1)S(=O)(=O)N1CCC(O)C1 +COc1ccc(OCCSc2nnc(-c3ccoc3C)n2C)cc1 +c1ccc(-n2ncc3c(N4CCOCC4)ncnc32)nc1 +CCOCc1cccc(CNC(=O)c2cnn(C)c2)c1 +C=C(C)CN(CC)C(=O)c1ccc(Br)cc1F +CN(C(=O)c1cccc(-n2cccn2)c1)c1ccc(Cl)cn1 +COc1ccc(C(=O)NC(C)Cc2ccccc2F)cc1 +CCC(c1ccncc1)n1ccnc1-c1cnc(-c2cccs2)nc1 +CCOC1CCCN(c2ccc(N)c3nonc23)C1 +Cc1cn2c(nc3c2c(=O)n(Cc2ccccc2Cl)c(=O)n3C)o1 +Cn1nnnc1SCCOC(=O)Nc1ccc(Cl)cc1 +O=C(CSc1ccc(-c2ccncc2)nn1)NCc1ccco1 +COC(=O)c1cn(CS(N)(=O)=O)c2ccc(C)cc12 +CS(=O)(=O)N1CCC(OC(=O)c2scnc2C2CC2)CC1 +CC(C)Oc1ccc(COC(=O)C(C)N)cc1F +Cc1cc(=O)c2cc(C(=O)Nc3ccnc4ccc(F)cc34)ccc2[nH]1 +CCN(CC(=O)NCc1ccc(F)cc1)C(=O)c1ccc(OC)cc1 +Cc1n[nH]cc1CNS(=O)(=O)c1ccc(F)cc1F +Cc1nn(CCO)c2oc(=O)cc(C(F)(F)F)c12 +COc1ccc(CCN2CCCC2=O)cc1C(C)C +CCn1c(CNCc2cccc(Cn3cccn3)c2)nc2ccccc21 +O=C(CC1CCOc2ccccc21)Nc1ncn(Cc2cccnc2)n1 +CCC(NC(=O)CN(C)S(C)(=O)=O)c1cccc(Cl)c1 +CCOCC1CCCC12CN(Cc1ccc(F)cc1)CCO2 +Cc1ccc(C(O)C(=O)Nc2ccc3c(c2)OCO3)cc1C +CCN(CC)C(=O)c1ccc(Cl)c(NC(=O)c2cnc(C)cn2)c1 +Cc1ccccc1C(=O)N1CCC(OCC(C)C)CC1 +COc1ccc2c(CC(=O)NCC(C)C)coc2c1 +CCCc1nnc(NC(=O)N2CCCC(NC(C)=O)C2)s1 +O=C(Nc1cccc(OCc2cccnc2)c1)N1CCCC1 +O=C(c1ccnnc1)N1CCC(Cn2cc(-c3ccccc3)nn2)CC1 +Cc1nnc(COC(=O)c2cccc(NC(=O)c3cccs3)c2)o1 +O=C(c1ccc(-n2ccnn2)cc1)N(C1CCCC1)C1CC1 +CC(Cc1cccs1)NC(=O)COc1ccc(F)cc1 +CCn1nc(C)c(Cl)c1C(=O)Nc1cccc(OC)c1 +O=C(Cn1nnc(COc2ccccc2)n1)N1CCOC2CCCC21 +Cc1ccc(NC(=O)c2ccc(F)cc2)cc1NC(=O)C1CC1 +N#CCSc1nccn1-c1ccc(F)c(F)c1F +CC(C)Oc1ccc(CNS(=O)(=O)c2ccc(F)cc2)cn1 +CCC(=O)N1CCc2sc(C(=O)NCCC(C)C)cc2C1 +c1ccc(OCCn2ccnc2-c2cnc(-c3ccccn3)nc2)cc1 +CCOc1ccc(OC)c(-c2cc(C(=O)OC)no2)c1 +COc1c(C)cnc(CNC(=O)Cc2c(C)nc(C)[nH]c2=O)c1C +CCOC(=O)C1(O)CCN(C(=O)Nc2ccc(CC)cc2)CC1 +Cc1cc(NC(=O)c2ccccc2)c2cc(F)ccc2n1 +COCCN(CCC#N)c1ncccc1Br +COc1ccc(OC)c(C2CC(O)=Nc3n[nH]cc32)c1 +C=CCN(Cc1ccco1)S(=O)(=O)c1ccc(Cl)cc1 +CCCn1ncc(-c2ccc(C)cc2C)c(CC#N)c1=O +O=C(CC1CCCCC1)N1CCN(C(=O)NCc2ccccn2)CC1 +O=C(Oc1ccc2ccc(=O)oc2c1)c1ccc2c(c1)OCCO2 +CC(C)(C)c1noc(CCC(=O)N2CCCC2c2cccs2)n1 +CCc1noc(C(C)S(=O)(=O)c2nc(-c3ccccc3)cs2)n1 +COc1cccc(-c2cc(N)n(-c3ccc(C)cc3)n2)c1 +CC(C)OC(=O)Cc1nc(CSc2ncc3ccccn23)cs1 +COC(=O)N(C)c1ccc(NC(=O)COC2CCCCC2)cc1 +Cc1nc(N2CCN(C(=O)C(C)C)CC2)c2c(n1)c(C)nn2C +O=C(Nc1ccccc1-n1ccnc1)c1cc(C2CC2)[nH]n1 +Cc1onc(-c2ccccc2)c1-c1ccnn1C(=O)NC(C)C +COCCCNC(=O)NCCn1c(C)nc2ccccc21 +Cc1ccc(NC(=O)CNc2ccccc2C#N)cc1 +CCOc1ccccc1C(=O)NCc1cccc(-c2n[nH]c(C)n2)c1 +CCOC(=O)c1sc(NC(=O)Cn2c(C)csc2=O)nc1C +Cc1cc(CN(C)C(=O)CCCNC(=O)C2CC2)no1 +CC(NC(=O)NCCCc1n[nH]c(N)c1C#N)c1ccccn1 +CC1CN(c2ncc3c(n2)CCCC3=O)CC(C)O1 +CC(c1cccs1)N(C)S(=O)(=O)c1cnc(N)nc1 +CC(C)(C)OC(=O)N1CCC(C(=O)OC2CCCCC2C#N)C1 +O=C(NCC(O)c1ccccc1)c1cc(Cl)ccn1 +O=C(c1ccon1)N1CCC(Cc2ccccc2)C1 +CN(C(=O)c1cc2c(s1)CCOC2)c1cccc2ncccc12 +CS(=O)(=O)c1cccc(C(=O)NCC(=O)N2CCCC2)c1 +Cc1cc(C)n(-c2ccc(=O)n(C(C)C(=O)NCc3ccco3)n2)n1 +COc1ccccc1C(=O)Nc1cccc(-c2noc(C)n2)c1 +Clc1ccccc1CNc1ncnc2sccc12 +Cc1ccc2[nH]c(CN3CCC(C)(O)C(O)C3)cc(=O)c2c1 +COc1cc2nc3c(cc2c(OC)c1OC)c(N)nn3C +COc1ccc(CCC(=O)NC(C(N)=O)c2ccccc2)cc1 +O=C(c1ccn(COc2ccccc2Cl)n1)N1CCOCC1 +CC1CN(CCCNC(=O)Nc2ccc(F)c(F)c2F)CC(C)O1 +CCC(NC(=O)c1ccc(Cl)cc1)C(=O)N1CCNCC1 +CC(C)(C)C(O)c1ccc2c(c1)C(NC(=O)C1CC1)CCC2 +Cc1ccc(-c2n[nH]c(NC(=O)C3CCOCC3)n2)cc1 +CCn1c(=NC(=O)C2CCC(=O)NC2)[nH]c2ccccc21 +Cn1ccn2ncc(C(=O)NCc3cn4c(n3)SCC4)c12 +CCS(=O)(=O)c1ccc(C(=O)N2CCC(=O)CC2)cc1 +OCc1nnn(Cc2ccccc2)c1-c1ccco1 +Nc1cccc(-c2nnnn2-c2cc(Cl)cc(Cl)c2)c1 +CC(C)c1nn2c(C#N)c(-c3cc(F)ccc3F)nc2s1 +O=C(NCCOc1cccc(Cl)c1)c1ccc(=O)[nH]c1 +CS(=O)(=O)c1ccc(C(=O)Nc2ccc(F)c(F)c2)cc1 +Fc1ccc(Cn2ncc3c2CN(c2ncc(F)cn2)C3)cc1 +O=C(c1ccccc1)N1CC(=O)N2CCc3ccccc3C2C1 +Cc1oncc1C(=O)N1CCC2C1CC(=O)N2c1cncnc1 +Cn1c(C(=O)NCc2ccc3c(c2)OCO3)nc2ccccc2c1=O +Cc1ccncc1NC(=O)NCCc1nc(C)c(C)s1 +CC(C)NC(=O)N1CCN(S(=O)(=O)N(C)C2CCCCC2)CC1 +COc1ccc(C)cc1NCc1nnc(-c2ccccc2)o1 +CCOC(=O)c1cnc(-c2ccccc2F)nc1N +O=C(Cc1cccc2ccccc12)NCC(=O)N1CCOCC1 +CC(CO)C(C)NC(=O)NC1CCN(c2ccccc2)C1 +Cc1nn(CC(=O)n2nnc3ccccc32)c(C)c1Cl +Cc1cc(NC(=O)Cn2nnc3ccccc3c2=O)ccn1 +O=C(c1cc2ccccc2oc1=O)N1CCOC12CCCCC2 +N#Cc1ccc(-n2sc3ccccc3c2=O)cc1 +CC(=O)Nc1nc2c(s1)CN(Cc1cc(F)ccc1F)CC2 +O=C(c1ccc(OCC2CCCN2C(=O)C2CC2)cc1)N1CCCC1 +O=C(Nn1cc(Br)cn1)c1noc2c1CCCC2 +COc1ccccc1-c1ccc(C#N)c(=O)n1CCO +CN(C)S(=O)(=O)NCc1ccccc1-n1ccnc1 +CN(Cc1ccc(Cl)cc1)C(=O)c1ccccn1 +CC(c1ccccc1)c1nccn1Cc1ccccn1 +CNC(=O)c1ccc(C(=O)N(C)C)cc1OC1CC1 +CC(=O)N(C)C1CCN(C(=O)c2n[nH]c3ccccc23)CC1 +Cc1oc(C2CCN(C(=O)C3CC3)CC2)nc1C(=O)N1CCOCC1 +COc1ccc(CC(=O)NC(C)c2ccco2)cc1 +O=S(=O)(c1ccc(NCc2ccccc2F)nc1)N1CCCCC1 +CC1c2cccn2CCN1CC(=O)NC1CCCCC1 +CC(C)(C)OC(=O)N1CCC(Sc2cccc(N)c2)C1 +CN(C(=O)COc1ccc(CC(N)=O)cc1)c1ccc(Cl)cn1 +Cc1cnn(C2CCCN(C(=O)c3cc4cccc(C)c4o3)C2)c1 +CC(C(=O)NC1CC1)N1CCN(c2ncccc2C(F)(F)F)CC1 +CCNc1nn(-c2ccccc2)c2c1C(=O)CC(c1ccco1)C2 +CCOCCN1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 +Cc1nc2ccccc2n(CC(=O)N2CCCCCC2)c1=O +Cn1ncc2c1CCCC2NC(=O)Cc1noc2ccccc12 +CN(C(=O)COC(=O)c1ccccc1Cl)c1ccccc1 +Cn1c(CNC(=O)Cc2cccc3ccccc23)nc2ccccc21 +Cc1ccc(C)c(C(=O)c2ccccc2C(=O)NCC(=O)N(C)C)c1 +CCOC(=O)N1CCN(c2ccc(OC)c3nc(N)nn23)CC1 +O=C(COc1cc(Cl)cc(Cl)c1)NC1CC1 +CC(=O)Nc1cc(C(C)(C)C)nn1-c1ccccc1 +Cc1cccc(C(=O)N2CCC(CCn3cccn3)CC2)n1 +O=C(Nc1ccc(OS(=O)(=O)c2ccccc2)cc1)c1ccco1 +O=C(N1CC(CO)C1)C1(c2ccc(Br)cc2)CC1 +Cc1cc(NC(=O)N(C)CC2CCC2)c2ncccc2c1 +Cc1ccc(CN2CCN(CC(=O)NC3CCCCC3)CC2)s1 +O=C(OCC=Cc1ccccc1)C1COc2ccccc21 +Cc1cc(C)c(NC(=O)N2CCN(C(=O)c3ccco3)CC2)c(C)n1 +CCCN(CCC)C(=O)c1cccc(C(=O)Nc2nccs2)c1 +O=C(Nc1ccc(-n2ccnc2)nc1)c1cc(-c2cccs2)n[nH]1 +CC1CN(C(=O)c2cnc3ccccn3c2=O)CC(C)O1 +Cc1cnc(N2CCOC3CC(COCc4ccncc4)CC32)nc1 +Cn1c2ccccc2n2c(=O)n(Cc3ccccn3)nc12 +CC(=O)c1ccccc1NC(=O)C1CC(=O)Nc2ccccc21 +COc1ncc(NCc2cnc(-c3cccs3)s2)cc1C(N)=O +c1csc(-c2nc(Cn3nccc3-c3ccncc3)co2)c1 +Cc1ncc(C(C)NCC(=O)N2CCN(c3ccccc3)CC2)s1 +O=C(COCC1CC1)NCc1cccc2ccccc12 +CS(=O)(=O)N1CCC(OCC2CC2)C1Cc1ccccc1 +CC=CCOC1CCCN(C(=O)c2ccc(Br)cc2)C1 +C=CCc1ccc(OCC(=O)N2C(C)COCC2C)c(OC)c1 +O=S(=O)(NC1CCC(O)CC1)c1c(F)cccc1F +CC(=O)NCC(=O)NCC(C)(C)c1ccc(Cl)cc1 +CC(C)NC(=O)CNC(=O)NC1Cc2ccccc2C1 +CC(CC(=O)N(C(C)C)C1CCOCC1)c1ccccc1F +CCCCS(=O)(=O)NCc1ccc(NC(N)=O)cc1 +C=CCNC(=O)c1cc(N(C)S(C)(=O)=O)ccc1Cl +CC(C)C(=O)NC1CCN(C(=O)c2csc3c2CCCO3)C1 +COc1cc(CNC(=O)N2CCc3ccccc32)ccn1 +Cn1cc(NC(=O)c2cnn(-c3ccc(Cl)cc3)c2)cn1 +O=C1OC(C(=O)N2CCN(c3nccs3)CC2)Cc2ccccc21 +Cn1ccnc1Sc1ccc(NC(=O)Cc2ccon2)cc1 +Cc1cc(NC(=O)COc2ccc(C)c(C)c2)n(CCC#N)n1 +CCN(c1ccc(-c2csc(NC3CC3)n2)cc1)S(C)(=O)=O +COCc1ccc(CN2CCN(C(=O)c3cccc(O)c3)CC2)o1 +COc1ccc(SCC(=O)NCC(C)(O)c2ccsc2)cc1 +N#Cc1ccccc1Cn1c(C#N)nc2ccc(F)c(F)c21 +CCOC(=O)c1cnc2c(c(C3CC3)nn2C)c1N1CCOCC1 +CC(C)S(=O)(=O)c1ccc(C(=O)Nc2ccc(F)cc2F)cn1 +Cc1cc(-c2nsc3c2C(=O)CC(O)C3)no1 +CC(Sc1nc2ccccc2c(=O)n1C)C(=O)N1CCOCC1 +COCCNC(=O)NC(C)COc1ccccc1C +COc1cccc2cc(C(=O)Oc3ccc(-n4cnnn4)cc3)oc12 +N#CCC(=O)Nc1ccc(C(=O)OCc2nccn2C(F)F)cc1 +COc1cccc2c1OCC(C(=O)NCCSc1cn[nH]n1)C2 +CC(NC(=O)CCC(C)(C)C)c1ccc(-n2cncn2)cc1 +FC(F)(F)Cn1ccnc1CSc1c[nH]nn1 +CC(=O)c1cccc(NC(=O)CC(C#N)C(C)C)c1 +CCOC(=O)CN(CC(F)(F)F)C(=O)c1coc2ccccc12 +CCc1cccc(NC(=O)NCc2cc(C(=O)OC)c(C)o2)c1 +COc1cc2c(cc1O)C(c1cncc(F)c1)NCC2 +Cc1nc2oc3ccccc3c(=O)c2cc1C(=O)NC(C)(C)C +Cc1cccc(OC2CN(C(=O)c3ccc(F)c(C)c3)C2)c1 +COCc1ncc(-c2cn(CCN3CCCC3=O)nn2)cn1 +CCOc1ccc2cc(S(=O)(=O)N3CCN(C)CC3)ccc2c1 +O=C(CC1Sc2ccccc2NC1=O)NCCc1cccs1 +CSc1ccc(C(=O)N2CCNC(=O)C2)cc1 +CC(C)N(C)C(=O)c1coc(COc2ccc(F)cc2)n1 +COC(=O)c1cc(CNc2nnc(C3CCCCC3)o2)c[nH]1 +Cc1cccc(CC(=O)N(C)Cc2cccnc2)c1 +Nc1ccc2c(c1)N(C(=O)c1cccc(Cl)c1)CCO2 +Cn1cc(C(=O)NCc2ccncc2)c(=O)c2cccc(Cl)c21 +N#Cc1cnn(C(=O)Cc2c(F)cccc2F)c1N +N#Cc1ccccc1OCC(=O)N1CCN(Cc2ccccc2)CC1 +NC(=O)c1cccc(S(=O)(=O)NC2CCc3ccccc32)c1 +O=S(=O)(c1ccc(Cl)c(Cl)c1)N(CCO)CCO +O=C(NCCc1ccccn1)Nc1ccn(Cc2ccccc2)n1 +CCS(=O)(=O)Nc1cnn(CC(F)(F)F)c1 +COC(=O)Cn1nc(-c2ccccc2F)c2c1CCN(C)C2 +CCN(CC)C(=O)C1CCCN1c1ncnc2c1cnn2C +OCc1cnnn1-c1nc(-c2ccccc2)cs1 +CC(=O)c1cccc(NC(=O)C(C)n2nc(C)ccc2=O)c1 +O=C(CCNC(=O)c1ccco1)Nc1ccccc1N1CCOCC1 +CC(Cc1ccsc1)NC(=O)c1ccc(O)c(Cl)c1 +Cc1cc(NC(=O)CSc2ccc(F)cc2)ccn1 +CC(C)c1cc(Br)ccc1NC(=O)NC(C)(CO)CO +CCCN(CCC)C(=O)Cc1csc(CC)n1 +CNc1nc(-c2csc(-c3ccc(OC)cc3)n2)cs1 +O=C(c1ccccc1)N1CC(c2nc(-c3ccccc3)no2)C1 +COc1ccc2c(c1)C(CC(=O)NC1CC1)CC2=O +CCOC(=O)C(C)NC(=O)C(C)NC(=O)c1cccc(C)c1 +CCc1ccc(S(=O)(=O)NCCOc2ccccc2)s1 +CC(Oc1ccccc1)C(=O)N1CCCc2ncccc21 +O=C(c1cnc(Cc2ccccc2)s1)N1CCC2(C1)OCCO2 +CCc1ccc(CNC(=O)c2ccc(C(=O)OC)nc2)s1 +c1coc(-c2nc3nc4c(c(NCc5cccs5)n3n2)CCC4)c1 +COc1ccccc1NC(=O)COC(=O)c1nccnc1N +COc1ccc(C(=O)N2CCC(CN3CCOCC3)CC2)cc1OC +COc1ccc(-c2nn3c(C(C)C)nnc3s2)cc1OC +COc1cc2c(cc1O)C(C(CO)c1ccccc1)NCC2 +O=C(CC1C=CCC1)NCc1cnn(-c2ccccc2)c1 +O=C1CCc2cc(NC(=O)c3ccc4[nH]cnc4c3)ccc2N1 +Cc1ccccc1SCC(=O)N1CCN(C(=O)c2ccco2)CC1 +Cc1ccc(CC(=O)Nc2c[nH]cc(Br)c2=O)cc1 +COCC(C)NC(=O)N1CCN(C(=O)C(C)(C)C)CC1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)N1CCC(O)C1 +COc1cc(C(=O)N(C)C2(C#N)CCC2)cc(OC)c1OC +O=C(Nc1ccc(Cn2cnc3ccccc32)cc1)c1csnn1 +NC(=O)NCCC(=O)NCCc1ccccc1F +COCc1cccc(CNC(=O)c2cc(F)ccc2F)c1 +CN(Cc1ccc(OCc2cccs2)cc1)C(=O)Cn1cccn1 +COc1ccc2cc(C#N)c(SCC(=O)NC3CCCC3)nc2c1 +Cc1ccsc1CNC(=O)CCc1ccccn1 +Cc1cc(=O)c(C2NCCc3cc(F)ccc32)c[nH]1 +COc1cc(C)c(C(=O)Nc2ccc(C)cc2O)cc1OC +Cc1ccc(NC(=O)c2nnn(-c3ccccc3)c2N)c(C)c1 +CCc1cccc(S(=O)(=O)NCc2c(CC)noc2CC)c1 +CC(C)c1[nH]nc(C(=O)NCCc2ccsc2)c1N +CC(C)c1nnc(NC(=O)CCC(C)(C)C)s1 +COCc1nc(C(=O)OCc2sc(C)nc2C)cs1 +Cc1cc2c(=O)n(CC(=O)N3CC(C)CC(C)C3)cnc2s1 +C#CCNC(=O)c1ccccc1NC(=O)CSc1ccc(F)cc1 +CCOc1ccc(NC(=O)c2ccoc2C)cc1CO +COC(=O)c1ccccc1NC(=O)C1CC(=O)N(C2CCCCC2)C1 +N#Cc1cccnc1SCC(=O)Nc1ccccc1C(N)=O +CC(C)C(C(=O)NCc1nnc2n1CCC2)c1ccc(Cl)cc1 +Cc1ncsc1C(=O)NC1CCN(c2ccc(C#N)cn2)CC1 +COc1ccnc(NC(=O)c2cccc(C)c2Cl)c1 +Cc1cccc(C(=O)NCC(=O)N2CC(C)c3ccccc32)c1 +CCc1ccc(CNC(=O)C2CCCN2C(=O)c2ccco2)s1 +CCCCn1c(=O)c2sccc2n(CC(=O)NCCC)c1=O +CC(C)Nc1nc(-c2csc(-c3cnccn3)n2)cs1 +Cc1c(-c2nnc3sc(C(C)C)nn23)cnn1C +O=C(Nc1ccccc1SCC(F)(F)F)c1cscn1 +O=C(c1ccco1)N1CCCn2nc(-c3cccnc3)cc2C1 +Nc1cc(NC(=O)Oc2ccccc2)ccc1Cl +Cn1cc(CC(=O)N2CCCCC2Cn2cccn2)c2ccccc21 +CCCN(CC1CC1)C(=O)C(C)NC(=O)Nc1ccccc1 +N#Cc1ccc(OCc2csc(-c3ncccn3)n2)c(Cl)c1 +CC1CCCN(C(=O)Nc2ccnc(C(=O)N(C)C)c2)C1CO +COCCNC(=O)NC1(c2ccc(Br)cc2)CC1 +CC(NC(=O)CSc1nccn1C)c1ccc2c(c1)OCO2 +Cc1c(CCNC(=O)NCC(C)(O)c2ccc(F)cc2)cnn1C +Cc1cccc(NC(=O)c2oc3c(c2C)C(=O)CC(C)(C)C3)n1 +O=C(CSc1cccs1)NCc1coc(-c2cccs2)n1 +CC(C)CC(=O)N1CCN(c2nccn2-c2ccccc2F)CC1 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1cnn(C)c1C +CCCCC1CN(c2cccc(C)c2)C(=O)CN1C(=O)COC +COc1ccccc1NC(=O)N1CCC(Oc2cnccn2)CC1 +Cc1ccc2nc(C3CCCN3C(=O)c3ccoc3C)[nH]c2c1 +COc1nc(Oc2ccc(Br)cc2)ccc1N +CCc1onc(C)c1NC(=O)N1CCCC(C)CC1 +CCc1noc(C)c1NC(=O)N(C)CCN(C)C(=O)OC(C)(C)C +COCCN(CCC#N)Cc1cccc(Br)c1 +N#CCCN(CCC#N)c1cc(Cl)cc(Cl)c1 +Cc1ccccc1CN(C)C(=O)CCNC(=O)c1ccc(F)cc1F +Nc1nc(Cn2cc(Cl)cn2)nc2sccc12 +COCCN(c1c(N)cccc1Cl)C(C)COC +CC1CC1NC(=O)N(C)CCN(C)C(=O)OC(C)(C)C +CC(=O)NC(CC(=O)NCCC(=O)N1CCCC1)c1ccc(C)cc1 +NC(=O)c1cc(-c2ccc(Br)cc2)nc(N)n1 +Cc1cc(C)cc(NC(=O)C(C)OC(=O)c2cccnc2)c1 +COc1ccccc1C(CNC(=O)c1cc(C)cs1)OC +Fc1ccc(-n2nnnc2-c2cn[nH]c2-c2ccccc2)cc1 +O=C(NCC(O)c1cccc(F)c1)c1cncc(Br)c1 +Cc1ccccc1NC(=O)Cn1nnc(C(N)=O)c1N +COc1cc(C)c(S(=O)(=O)NCCc2cnccn2)cc1C(C)C +CC(=O)N(Cc1ccc(NC(=O)NC(C)(CO)C2CC2)cc1)C(C)C +CCOc1ccc(CCC(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1ccc2nc(-c3cccnc3)c(C(C)O)n2c1 +CCc1nc(CNc2ccc(C(N)=O)cc2)cs1 +Cc1nn(C)c2ncc(NC(=O)c3cc(C(N)=O)cn3C)cc12 +O=C(NCc1ccc2c(c1)OCO2)c1csc(-c2cnccn2)n1 +O=S1(=O)COCCN1Cc1cccc(Cl)c1F +CC(NC(=O)c1ccncc1)c1ccc(Br)cc1 +CC(=O)Nc1ccc(NC(=O)c2c[nH]c3cccc(F)c23)cc1 +CC(C)C(NC(=O)c1cnn[nH]1)c1ccc(F)cc1 +COc1cc(S(=O)(=O)N2CCCCCC2)ccc1F +N#Cc1cnn(C(=O)c2cc3cc(Cl)ccc3o2)c1N +CN(CCCc1ccccc1)C(=O)c1cccc2[nH]ccc12 +CCCc1cc(=O)n(C)c(CC(=O)c2ccc(Cl)cc2)n1 +Cc1ccccc1C1(CNC(=O)c2ccc(=O)n(C)n2)CCOCC1 +Cc1ccccc1C1(O)CCN(C(=O)c2c[nH]c(=O)cn2)C1 +CC(C)NC(=O)Nc1cccc(C(=O)N(C)CC(F)(F)F)c1 +Nc1ccccc1Cn1ccnc1Cc1ccc(F)c(F)c1F +CCc1cc(C2CCCN2C(=O)CCc2ccccc2)on1 +CCCc1c(C(=O)N2CCOCC2)cnn1-c1cccc(F)c1 +Cn1c(CCNC(=O)c2cc(=O)c3ccccc3o2)nc2ccccc21 +O=C(NCCc1ccccn1)NCC1COc2ccccc2O1 +CC(C)CNC(=O)c1nnc2c(-c3cccnc3)ccnn12 +CCNC(=O)CN(CC)C(=O)c1ccc(Cl)cc1Cl +Clc1cccc(-c2nnc3n2NCCS3)c1 +CN(CCC(F)(F)F)C(=O)c1cnc2n(c1=O)CCS2 +COc1cccc(CCOc2ccc(CO)cc2)c1 +Cc1ccc(NC(=O)C2CC(=O)Nc3cc(C)nn32)cc1 +Cc1ncc(CNC(=O)NCCC(=O)NC2CCCC2)s1 +C=CCOc1cccc(CN(C)C(=O)c2cnccn2)c1 +Cc1ccc(S(=O)(=O)Cc2ccc(F)c(Br)c2)nc1 +COC(=O)C1CCc2c(nc(CO)n2CC(F)(F)F)C1 +Cc1nnc(SCC(=O)N2Cc3cnc(C(C)(C)C)nc3C2)s1 +C=CCNC(=O)C(C)Sc1cccc(Br)c1 +NC(=O)CNC(=O)CSc1cc(Cl)ccc1Cl +CCc1nnc(NC(=O)CCC(=O)Nc2cccc(OC)c2)s1 +COCc1ccccc1CNC(=O)Nc1cnn(C)c1 +CCc1nc(C2CCCN2c2nc(C(F)(F)F)ccc2C#N)no1 +Cc1ccc(C)c(Cn2nc(C3CC3)n(-c3ccccc3)c2=O)c1 +Cc1cc(CNc2ccc3c4c(cccc24)CC3)no1 +CCC(C)NC(C(=O)OC)c1cc(F)ccc1F +COCCOc1ccc(NC(=O)C(C)NC(C)=O)cc1 +Cc1n[nH]c(C)c1C1COCCN1Cc1ccc(C#N)cc1 +CCn1ccc(C(=O)N2CCC(Nc3nccnc3OC)CC2)n1 +CC(c1ccccc1)c1nc2ccc(O)cc2n1C +CC1C(=O)N(C)CCN1c1nc(N)nc2[nH]ncc12 +COc1ccc(NC(=O)NCC(C)(O)c2ccsc2)cc1Cl +Cc1nn(C)c(C)c1CNc1nnc(Cc2ccc3ccccc3c2)o1 +CC(=O)N1CCC(C(=O)N2CCCSc3ccc(Cl)cc32)C1 +CCCOCC(=O)NC(C)(C)c1ccc(F)cc1Cl +COc1ccccc1SC(C)C(=O)NCC(C)C +CCOc1ccc(F)c(C(=O)NC(CC)c2nccs2)c1F +O=S1(=O)CCCN1Cc1csc(C2CCCC2)n1 +Cc1c(C(C)NC(=O)C(C)NC(N)=O)oc2ccccc12 +CC(=O)NC(C(=O)N(CC(N)=O)C(C)C)C1CCCC1 +CC1CCCC(C)N1C(=O)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +COCCC1(CNC(=O)N2CCCCCC2)CCC1 +CN(CCOc1ccc(F)cc1)Cc1nc2sccc2c(=O)[nH]1 +CCNC(=O)c1ccc(NC(=O)Cc2cccc(OC)c2)c(C)c1 +Cc1cc(CN(C)C(=O)c2cc3ccccc3c(=O)[nH]2)no1 +CSc1ccc(Cl)cc1NC(=O)c1ccnnc1 +CCc1nnc2n1CCN(CC(=O)NC(C)(C#N)C1CC1)C2 +CC1Cc2ccccc2N(C(=O)c2cccnc2OCC(F)F)C1 +CCOc1ccc(S(=O)(=O)N(C)c2cc(F)ccc2F)cn1 +CCCN1C(=O)c2[nH]nc(-c3ccco3)c2C1c1cccc(O)c1 +CC(C)(NC(=O)CCN1CCOC1=O)c1cccc(C(F)(F)F)c1 +N#CC1(NC(=O)CSc2ccc(O)cc2)CCCCC1 +CN(CC(=O)Nc1ccccc1)C(=O)NCC(F)(F)F +N#Cc1cccc(CSc2nnc(NC3CC3)s2)c1 +O=C(Nc1nc2ccc(F)cn2n1)C1CSc2ccccc21 +CCOC(=O)c1nc(N2CCc3ccccc32)c2c(C)noc2n1 +Cc1c(CN2CC3OCCN(C)C3C2)cc(C#N)n1C +CCCNC(=O)Cc1csc(NC(=O)c2ccccc2)n1 +CCC(=O)NCC(=O)Nc1cccc(NC(=O)C(C)n2cccn2)c1 +CCS(=O)(=O)NCC(O)c1ccc(C)c(C)c1 +Cn1cc(CNCC(O)c2ccc(F)cc2)c(-c2cccnc2)n1 +O=C(Cc1c[nH]c2ccccc12)Nc1cccc(CO)c1 +CC1CCCCC1Nc1ccc(-n2cncn2)cc1 +CCS(=O)(=O)c1ccccc1C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +FC(F)(F)C(c1ccccc1)N1CCN(CC2OCCO2)CC1 +COCCNc1nc(-c2sc(N(C)C)nc2C)cs1 +Cc1ccc(CN2CCCN(CCCC#N)CC2)cc1 +Cc1nc(-c2ccc(C(=O)NC(C)C)c(F)c2)no1 +O=C(CCc1ccc(F)c(F)c1)NCc1cccnc1 +Cc1ccc(-c2nnc(SCC(=O)N3CCCC(C)C3)n2C)cc1 +c1cc2c(cc1-c1nc(C3CCOC3)no1)OCO2 +CCOC(=O)Cc1cnc(NC(=O)c2cc(C)cc(C)n2)s1 +COc1cnc(C2(O)CCN(C(=O)c3cc(C)no3)CC2)c(OC)n1 +COCCCNC(=O)c1ccc(Cn2nc(C)c(Cl)c2C)cc1 +CC1CN(Cc2c(C(C)C)[nH]c3ncccc23)CC(C)O1 +COC(=O)c1nc(-c2ccccc2)[nH]c1C(=O)OC +N#CC1(NS(=O)(=O)CCCc2ccccc2)CCOCC1 +CC1(C)COCCN1S(=O)(=O)c1cccnc1 +CC(CN1CCCC1=O)NC(=O)NCC1CC1C +CCC(=O)Nc1ccc(F)c(-c2nnc3n2CCCCC3)c1 +O=C(C1CCCCN1S(=O)(=O)c1cccs1)N1CCCCC1 +O=C(CN1C(=O)COc2ccccc21)Nc1cccnc1-n1cccn1 +COCCCn1ccc(NC(=O)c2scnc2C2CC2)n1 +COc1cccc(NC(=O)CN(C)C(=O)c2cc(C)oc2C)c1 +CCCCCNS(=O)(=O)c1cc(N)cc(F)c1 +Cc1ccc(F)cc1S(=O)(=O)Oc1ccc2ccc(=O)oc2c1 +CCc1c(C)nc(N2CCN(c3ccccc3F)CC2)[nH]c1=O +Cc1ccc(-c2ncco2)cc1NC(=O)c1cccc(-n2ccnn2)c1 +CCOc1ccc(OC(=O)C2COc3ccccc3O2)cc1 +Cn1c(N)nnc1SCC1CCC(C)(C)CC1 +O=C(CCn1cccn1)Nc1ccc(N2CCCC2)nc1 +CC(NC(N)=O)C(=O)N1CCCCC1c1ccc(C(F)(F)F)cc1 +CCn1cc(NC(=O)c2c(C)cc(C)cc2C)ccc1=O +CCC1CCCCC1NC(=O)c1ccc(OCC(=O)NC)c(OC)c1 +O=C(Cn1cc(Br)ccc1=O)N1CCCC(CO)C1 +Brc1cncc(NCCc2nc(-c3ccco3)n[nH]2)c1 +Nc1nc(N)nc(COc2ccc(Cl)cc2Br)n1 +N#CC(C(=O)CCOCC1CCCO1)c1nc2ccccc2[nH]1 +N#CCc1nc2cc(F)ccc2n1CCN1CCOCC1 +CCN(CC1CC1)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CNC(=O)C1CCCCN1C(=O)c1ccc(NC(=O)C2CC2C)cc1 +Cn1c(C(=O)NCCNC(=O)c2ccccc2F)cc2ccccc21 +Cn1nc(C(=O)NC2CC2)c2c1-c1ccccc1SC2 +O=C(OCc1cnn(-c2ccccc2)c1)c1ccc(O)cc1O +OC(CN1CCCc2ccccc21)c1ccncc1 +COc1ccc(Cl)cc1NC(=O)CSc1ccccn1 +CC(=O)c1cccc(S(=O)(=O)NCC(O)C2CCCCC2)c1 +CCc1ccc(C(=O)OCC(=O)Nc2sccc2C(N)=O)cc1 +COCc1nc(C(=O)NC2CC2c2cccc(Cl)c2)cs1 +COc1cc(COC(=O)c2cnc3[nH]c(C)nc3c2)ccc1F +COc1cc(C#N)ccc1OCC(=O)NC1C2CCOC2C1(C)C +CSc1ccccc1C(=O)NCCCn1cnc2ccccc21 +COC(=O)c1cc(S(=O)(=O)NC2CCC(C)CC2)c(C)n1C +COc1ccc(C(=O)NCc2cc3ccccc3n2C)cc1 +O=c1c(-c2ccc3ccccc3n2)coc2cc(O)cc(O)c12 +Cc1ncsc1C(=O)N1CCN(Cc2ccccn2)CC1 +Cc1sc2ncnc(NCCC(=O)N(C)C)c2c1C +COc1cccc(CNc2ccc3c(c2)OCC(=O)N3)c1 +CC(=O)Nc1ccc2c(CN(C)Cc3cnn(C)c3)cc(=O)oc2c1 +COc1cc(-c2nc3sccc3c(=O)[nH]2)ccc1O +CCc1nccn1CCN1CCN(CC(=O)N2CCOCC2)CC1 +Cc1ccc(OC2CCN(C(=O)C(C)C)CC2)nn1 +COc1cccc(N2CCN(C(=O)c3sc(C)nc3C)CC2)c1 +CC(C)n1ncc2ccc(NC(=O)c3ccccn3)cc21 +N#Cc1c(N)nc2c(c1-c1ccc(F)cc1)c(=O)nc1sccn12 +Cc1n[nH]c(C2CN(CCn3cnc4ccccc4c3=O)CCO2)n1 +CCOCC1CCCN(C(=O)c2cccn2C)C1 +CNC(=O)c1cc(C)ccc1NC(=O)c1cc(C)no1 +Nc1ccccc1Sc1ncnc2c1ncn2Cc1ccccc1 +Cc1ccc2ncc(C(=O)NCc3ccc(F)cc3)c(=O)n2c1 +CC(C)(CO)NC(=O)CN1CCN(c2ccc(F)c(F)c2)C1=O +COC(=O)C(C)NC(=O)c1ccc(F)cc1NC(=O)c1ccco1 +O=C(NCC(=O)N1CCc2ccccc21)NCC(F)(F)F +CCOC(CC)C(=O)NCCn1cnc2ccccc21 +COc1cc(OC)c(NC(=O)c2ccco2)cc1Cl +CNC(=O)Nc1ccc(OC)c(OC2CCCC2)c1 +CSc1nc(OC(F)F)cc(OC(F)F)n1 +CN(CC(=O)OC(C)(C)C)C(=O)c1cc(-c2cccs2)on1 +NC(=O)C1CN(C2CCN(c3ccccc3)C2=O)CCO1 +Cn1ccc(NC(=O)c2cc(NC(=O)Cc3ccccc3)n(C)n2)n1 +CC(=O)c1ccc(OCC(=O)NC2CCCCC2C)cc1 +COc1cc(C)c(C(C)NC(=O)c2cccc(C)n2)cc1OC +CC(=O)NCCNC(=O)c1sc(-c2ccc(F)cc2)nc1C +NC(=O)C1CCCN(C(=O)c2cc(Cl)ccc2O)C1 +O=C(Cc1ccccc1)N(Cc1ccccn1)Cc1ccco1 +C#Cc1cccc(NCc2cccc(OC)c2OC)c1 +CCCc1nnc(SCC(=O)Nc2nccs2)o1 +FC(F)Oc1ccc(CNc2ncnc3sccc23)cc1 +CCCCCC(=O)Nc1ccc(C(=O)Nc2cccnc2)cc1 +Cc1noc(C)c1CCC(=O)Nc1ccccc1-n1cnnn1 +O=C(Nc1ccc(COC2CCCC2)cc1)N1CCC(O)C1 +CNC(=O)c1ccc(OC(=O)C=C2CCCCC2)cc1 +COc1ccc(C)cc1-n1ccc2c(nnc3ncnn32)c1=O +Cc1ccn2ncc(C(=O)NCCNC(=O)NC(C)C)c2c1 +O=C(Nc1nc2ccc(F)cn2n1)c1cccc2ncccc12 +CC1CN(Cc2ccc(F)cc2C#N)CC(C(N)=O)O1 +COCCn1nc(C(=O)N(C2CC2)C(C)C(C)C)ccc1=O +CC1(NC(=O)Nc2ccc(-n3ccnn3)cc2)Cc2ccccc2C1 +Cc1ccc(-n2cc(C)cn2)c(NCc2cc(C#N)cs2)c1 +N#Cc1ncn(CC(=O)c2ccc(C3CCCCC3)cc2)n1 +Cc1cnc(C(=O)NCCc2c[nH]c3ccccc23)cn1 +CCCCCOc1ccccc1-c1nc(N)nc(C)c1C(=O)N(C)C +Cc1ccccc1NC(=O)CSc1nnc(-c2cccs2)n1C +C=Cc1ccc(S(=O)(=O)c2ccc(O)cc2)cc1 +CCN1C(=O)c2cc(C(=O)NC)nn2CC1(C)C(=O)NC1CCCC1 +Cc1ccc(CN(C(=O)CNc2c(F)cc(F)cc2F)C2CC2)o1 +CCCC(=O)Nc1ccc(C(=O)NCc2ccccc2F)cc1 +Cc1cccc(OCC(O)CNC(=O)c2ccc(=O)n(C)c2)c1 +CCOc1cc(F)ccc1NC(=O)c1[nH]ncc1Br +Cc1ccccc1C(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2 +Cc1c(C(=O)N(C)CCC#N)sc2ncn(C)c(=O)c12 +CC1CCCC(C(=O)NC2CCCN(Cc3ccccc3)C2=O)C1 +Cc1cc(NC(=O)NCCC2CC3CCC2C3)no1 +COc1ccc(C(=O)Nc2c(C)nc3ccc(C)cn3c2=O)cc1 +O=C(Cn1nc(-c2ccccc2)oc1=O)NCC1CCC1 +O=C(c1ccccc1Cl)N1CCC(CO)CC1 +COC(=O)C(C)NS(=O)(=O)c1ccc(Cl)c(N)c1 +CC1CCc2c(sc3ncnc(N4CCNC(=O)CC4)c23)C1 +CC(C)CNC(=O)c1ccc(NC(=O)CNC(=O)C(C)(C)C)cc1 +O=C(NCc1cn2ccccc2n1)c1ccccc1F +CCOC(=O)C1(C#N)CC2CC1CN2C(=O)OCc1ccccc1 +CCNC(=O)N(C)Cc1ccc(C(=O)OC)cc1 +CC1Oc2ccc(N)cc2N(CCOc2ccccc2)C1=O +CCOC(=O)NCC(=O)Nc1nc2ccccc2[nH]1 +COCc1ccccc1CNC(=O)NC1(C)Cc2ccccc2C1 +COc1ccccc1OC1CN(C(=O)c2cccc3cc(C)oc23)C1 +O=C(Nc1cccc2cn[nH]c12)c1cc2cc(F)ccc2[nH]1 +O=C(NCC1(c2ccccc2)CC1)NC1CC2CCC1O2 +CCOC(=O)N1CCN(C(=O)C2CCC(=O)N2Cc2ccco2)CC1 +COc1cc(Nc2ccc(C#N)cn2)cc(OC)c1 +COC(=O)c1c[nH]c2ccc(Br)cc12 +O=C(CNC(=O)c1ccc(F)c(F)c1)Nc1ccc2c(c1)COC2 +CC(=O)NCCCNC(=O)NC1CCC(C)CC1 +Cc1cnc(C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)cn1 +CC(C)(C)c1ccc2c(c1)CNCC2NC(=O)c1ccncc1 +CCN(Cc1cnn(CC)c1)c1nc2c(s1)c(C)nn2C +CCCNC(=O)Cn1c(C)ccc(NC(=O)CCC)c1=O +COC(=O)c1cccc(C(=O)NCc2n[nH]c(C)n2)c1 +CCc1ncc2c(n1)CN(c1ncccc1C(=O)N1CC3CCC1C3)C2 +COCCN(C)C(=O)c1cc(-c2ccccc2F)on1 +O=C(Nc1ccccc1)c1c(F)c(F)cc(F)c1F +Cn1c(=O)c2c(ncn2CC(=O)Oc2ccccc2F)n(C)c1=O +O=C(CSc1ccccc1)Nc1nncs1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1cccc(O)c1 +COc1ccccc1CC1CCCN1C(=O)c1ccc(=O)n(C)c1 +CS(=O)(=O)c1ccccc1C(=O)NC1CCc2ccccc21 +CSc1ccc(C(=O)N(CCO)C2CC2)cc1 +CCCn1c(N)c(C(=O)CN2CCN(C(C)=O)CC2)c(=O)[nH]c1=O +N#CC1CCCN(Cc2c(F)cccc2Cl)C1 +CC(=O)Nc1ccc(O)c(C(=O)NCc2cc3ccccc3o2)c1 +CS(=O)(=O)N1CCC(Oc2cccnc2)CC1 +CC(NC(N)=O)C(=O)N1CCN(c2ccc(F)cc2)CC1 +CCn1nnnc1-c1cccc(C(=O)NCCCn2cccn2)c1 +CC(C)(C)c1cc(NC(=O)CNc2ccccc2C(N)=O)on1 +O=C(c1ccco1)N1CCCn2nnc(COc3cccnc3)c2C1 +COc1ccc(C(=O)Nc2cnn(C(C)(C)C)c2)cc1 +Cn1cnnc1-c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +CS(=O)(=O)c1ccc(Cl)c(NC(=O)c2ccc(Cl)cc2)c1 +Cc1ccc(C)c(NC(=O)NCc2nnc3ccccn23)c1 +CCn1cc(NC(=O)c2nn(-c3ccccc3)cc2OC)ccc1=O +COc1ccc(-n2ccc(CNC(=O)NCCNC(C)=O)n2)cc1 +Cc1ccccc1C(=O)Nc1cnc2c(C)cccn2c1=O +CCC(C)NC(=O)CN1CCN(C(=O)Nc2ccc(C#N)cc2)CC1 +Cn1nc(CNC(=O)c2cc(-c3ccccc3)on2)c2c1CCCC2 +COc1ccc(C(=O)NC2CCCC(C)C2)cc1OC +Cc1cn2nc(SC3CCc4ccccc43)sc2n1 +O=C1CCCN1CCCNC(=O)N1CCc2sccc2C1 +NC(=O)c1ccn(-c2ccccc2NC(=O)CCc2ccco2)n1 +Cc1cc(C(=O)NC2CCCc3ccccc32)no1 +COc1cccc2cc(CN3CCN(c4cnn(C)c4)C(=O)C3)oc12 +COc1ccc2c(c1)CCCN2C(=O)c1c(C)noc1C +CCn1nccc1C1CCCN1S(=O)(=O)c1ccc(F)cc1 +Cc1ccccc1C(=O)N1CCC(C(=O)NC(C)C(C)C)CC1 +Cc1c(C(N)=O)nnn1-c1ccc(C(F)(F)F)cc1Cl +OCCN(Cc1ccccc1)CC(O)c1ccc(F)cc1 +CCN(CC)C(=O)CCC(=O)Nc1cc(-c2cccs2)n[nH]1 +COc1ccc(OC)c(C(O)CNC(=O)c2cc(F)ccc2C)c1 +CCOC1CCC2C1OCCN2Cc1csc(C)n1 +CCC(CC)CNC(=O)NC(C)c1c(C)noc1C +N#Cc1cc(N)ncc1-c1ccc(Cl)cc1Cl +CCC(CC)N(CCO)S(=O)(=O)c1cccc(N)c1 +O=C(c1cccc2cn[nH]c12)N(Cc1cccnc1)CC1CCCO1 +CCOC(=O)N1CCN(C(=O)Cc2ccc(O)cc2)CC1 +COc1cccc(NC(=O)Nc2ccc3c(c2)oc(=O)n3C)c1 +CNC(=O)CNC(=O)c1nc(-c2ccccc2)n2c1CCCCC2 +COCC(O)CN(C)C(=O)c1ccc(-n2ccnn2)cc1 +Cn1nccc1C(=O)NC1CCN(S(=O)(=O)C(F)(F)F)CC1 +CCCN(C)C(=O)c1cnc2c(c1)nc(-c1ccccc1Cl)n2C +COC(=O)c1ccc(-n2cccn2)c(C#Cc2ccccc2)c1 +OC(CNc1ccccc1F)COc1ccc(F)cc1 +CC(=O)Nc1nnc(S(=O)(=O)NC(C)C)s1 +Cc1cccc(OC(C)C(=O)NC(C)c2ccc(C)o2)c1 +CC(C)n1nnnc1-c1cccc(C(=O)Nc2cccc(F)c2)c1 +CNS(=O)(=O)c1ccc(C(=O)NCC2CCC(C)(C)CC2)cc1 +CN(CCC(F)(F)F)C(=O)c1cc(C(C)(C)C)n[nH]1 +CC(C)c1cccc(OCC(CC#N)N2CCOCC2)c1 +CCOC(=O)c1cccc(NC(=O)CSc2nnnn2C)c1 +CC(C)NC(=O)Nc1cccc(C(=O)Nc2cccc3cnccc23)c1 +COc1cccc(OC)c1Oc1ccc(N)c(C)c1 +O=C(Nc1cc(-c2ccccc2F)no1)c1nccn2ccnc12 +Cc1nc(NC(=O)CCc2c[nH]c3ccccc23)n(C)n1 +COC(=O)Nc1ccc(CNC(=O)c2scnc2C2CC2)cc1 +CC1CCCC(C)N1C(=O)c1nc(-c2cnccn2)no1 +CC(C)C(=O)OC(C#N)c1c(F)cccc1Cl +CNC(=O)NCC(=O)N(C)Cc1nc2ccccc2s1 +C=CCN(CC(F)(F)F)C(=O)c1cccc2[nH]ncc12 +N#CCc1nc2cccnc2n1CCN1CCOCC1 +Cc1ccc(OCC(=O)N2CCN(c3ccccc3O)CC2)c(C)c1 +O=c1c2c([nH]c3ccnn13)CCN(S(=O)(=O)c1cccs1)C2 +O=S(=O)(Nc1ccccc1O)c1ccc(Br)cc1 +CC1CCCC(NC(=O)NCC(C2CCOC2)N2CCOCC2)C1 +Cc1ccc(NC(=O)COC(=O)c2ccc(C#N)cc2)cc1 +Cc1sc(NC(=O)c2ccc3ccccc3n2)c(C#N)c1C +Cc1cc2c(=O)n(CC(=O)NC(C)(C)C)ccc2s1 +CN(C)S(=O)(=O)c1ccc(C(=O)NCCCn2cccc2)cc1 +CC(C)Cn1c(Cn2ccnc2)nc2cc(NC(=O)C(C)C)ccc21 +Cc1cc(C)nc(N2CCCC2c2nc(C)no2)n1 +Cn1ccc2ccc(C(=O)NC3Cc4ccccc4C3)cc21 +O=C(CCc1ccccc1F)N1CCN(C2CCCC2O)CC1 +CN(C)C(=O)c1ccc(-c2ccc(OCc3ccccc3)nc2)nc1 +O=C(C1CCCC1)N1CCN(C(=O)C2(c3ccccc3)CC2)CC1 +COC(=O)c1sc(NC(=O)c2cc(OC)cc(OC)c2)nc1C +Cn1cnnc1CC1CCN(c2cnc3ccccc3n2)CC1 +O=C(Oc1cccc(F)c1)c1cnc(C2CCCO2)s1 +CC(c1ccccc1Cl)N(C(=O)c1ccn(C)c(=O)c1)C1CC1 +CC(=O)Nc1nc(C(=O)NCCOc2ccc(C)cc2)cs1 +COC(=O)CCc1nn2c(C#N)c(-c3cccs3)nc2s1 +CN(C)S(=O)(=O)NCCOc1ccc(F)cc1 +CC(NS(=O)(=O)c1cccc(C#N)c1)C(N)=O +Cc1ccc(-c2nc(C(=O)Nc3ccc(=O)n(C)c3)cs2)c(C)c1 +CCOC(=O)C1CCN(C(=O)c2cccc3ccccc23)CC1 +O=C(Nc1cccc(C(=O)N2CCOCC2C2CC2)c1)c1ccco1 +O=C(NCc1ccccn1)c1ccc2nc3n(c2c1)CCC3 +CCn1cnnc1CNC(=O)c1cnc(-c2ccccc2)s1 +CN(C)C(=O)c1cc(NC(=O)N(C)CCOCC2CC2)ccc1F +CNc1ncc(C(F)(F)F)cc1Br +COc1ccc(C2CC(=O)Nc3snc(C)c32)c(OC)c1 +O=C(NCc1cccnc1)C(Sc1ccccc1)c1ccccc1 +CC(c1ccc(S(N)(=O)=O)cc1)N(C)c1nc2ccccc2s1 +CCNC(=O)c1cccc(NC(=O)CNc2ccc(F)cc2)c1 +CNC(=O)CCCNC(=O)c1cccc(-c2ccc(O)cc2)c1 +Cc1cc(C)n2nc(C(=O)Nc3cc(F)c(F)c(F)c3)nc2n1 +Cc1nc(Cn2ncc(N3CCOCC3)cc2=O)co1 +Nc1c(-c2ccco2)nnn1-c1ccc(Cl)cc1 +Cc1n[nH]c(C)c1S(=O)(=O)N1CC2CCC1C2 +CCNC(=O)c1ccc(NCC(=O)NCC(F)(F)F)c(C)c1 +CNS(=O)(=O)c1cccc(C(C)Nc2cccc(F)c2)c1 +COC(=O)c1cccc(NC(=O)NCc2cccs2)c1 +CCCCN(C)C(=O)NCC(C)Cn1nc(C)cc1C +CCC1c2ccccc2CCN1C(=O)c1ccc(C)nc1 +CS(=O)(=O)c1ccc(NC(=O)NCC(O)c2ccco2)cc1 +Cc1ccc(NC(=O)c2ccccc2)cc1NC(=O)c1ccncc1F +CN(CC(=O)NC1CC1)C(=O)C1COc2ccc(F)cc2C1 +O=C(Nc1cc(-n2cccc2)ccc1F)C1CCCN1C(=O)C1CC1 +CCCc1cc(C(=O)NCC(O)c2ccc(F)cc2)[nH]n1 +CNC(=O)c1cccc(CN2CCOC(c3ccccc3Cl)C2)c1 +COc1cc(N)c2c(C(=O)Nc3ccncc3)nccc2c1OC +Nc1cc(Cc2ccc(Br)cc2)no1 +CCS(=O)(=O)c1ccc(O)c(NC(=O)c2ccoc2)c1 +CC(C)Oc1ccc(NC(=O)CNc2ccccc2C(N)=O)cc1 +O=C(NCc1ccc(F)cc1F)c1csc(Nc2cccnc2)n1 +Cc1cc(N)nc(SCC(=O)NCc2cccc(Cl)c2)n1 +N#Cc1ccc(C(=O)NCCCCN2CCOCC2)cc1 +O=C(c1cnn(-c2ccc(F)cc2)c1)c1ccccc1O +NC(=O)Cc1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1 +CCN(CC1CCOC1)S(=O)(=O)c1ccc2ncccc2c1 +CC(C)COC(=O)Nc1cccc(NC(=O)N(C)C(C)CC#N)c1 +CCCCN(CC)C(=O)Cn1nnc(-c2ccc(C)cc2)n1 +COC(=O)N(C)CC(=O)Nc1ccc2c(c1)Cc1ccccc1-2 +CSc1ccc(C(=O)NCc2csc(=O)[nH]2)o1 +Cn1c(SCCCO)nc2scc(-c3cccs3)c2c1=O +CC(C)OC(=O)C1C(c2ccc(O)cc2)c2c(O)n[nH]c2CC1(C)O +Cc1nc(-c2cccs2)sc1CNC(=O)COc1cccnc1 +CC(C)(C)NC(=O)c1snc(-c2ccccn2)c1N +Cc1ccc(NC(=O)CNC(=O)Nc2ccccc2)cc1C +Cc1ccc(NC(=O)N(CCC(F)(F)F)CC(O)CO)cc1 +Cc1ccc(CC(=O)Nc2ccccc2SCC(N)=O)cn1 +CCOCCCC(=O)N(C)Cc1cnc(C)s1 +CCCOc1ccc2c(c1)C(c1cc[nH]c(=O)c1)NCC2 +CCNC(=O)C(C)NC(=O)c1ccc(Br)cc1F +CNC(=O)C1CN(c2nc3ccc(OC)cc3s2)C1 +C#CCOC(=O)C1CCCN1C(=O)c1ccccc1OC(F)F +COCC(C)NC(=O)COc1ccccc1C(N)=O +CCCC1CN(C(=O)c2cc(C(C)C)nc3onc(C)c23)CCO1 +N#Cc1cccc(NC(=O)NCCS(=O)(=O)NCC2CCC2)c1 +Cc1nccn1-c1ccc(CNc2nc3ccccc3o2)cc1F +Clc1ccc(Cc2noc(-c3cnco3)n2)cc1 +CCCNc1ncc(C(=O)N2CCCC2C)cc1Cl +COc1ccc(-c2nc(Cn3cnc(C)n3)c(C)o2)c(C)c1C +CCC(C)NC(=O)COc1ccc(Br)cc1F +COC(=O)N(C)c1ccc(NC(=O)C(C)(C)C#N)cc1 +CCC(O)c1c(-c2cc(OC)ccc2OC)nc2cccc(C)n12 +Cc1nc(CNC(=O)NCc2nnc3n2CCCCC3)cs1 +Brc1cnn(-c2c[nH]c3ccccc23)c1 +Nc1c(-c2ccc(F)c(F)c2)nc2c(Cl)cccn12 +CCn1cc(NC(=O)N(C)Cc2ccc(Cl)cc2)cn1 +CCc1c(-c2cn[nH]c2)nn(-c2ccccc2)c1N +Cc1cc(S(=O)(=O)NC(C)c2nnc3ccccn23)c(C)s1 +CCc1onc(C)c1NC(=O)CCc1cccnc1 +O=C(NCCc1ccc(F)cc1F)NC1CCC2(CC1)OCCO2 +COCc1c(C(=O)NC(C)c2nncn2C)sc2cccc(F)c12 +O=C(CCc1nc(-c2ccccn2)no1)N=c1[nH]nc2ccccn12 +COc1ccc(C(C)=O)c(OC(=O)c2cccn2C)c1 +COc1ccnc(NC(=O)c2cccc(N(C)C)c2)c1 +NC(=O)C(NC(=O)Cn1ccc2ccccc21)c1ccccc1 +CCc1ncnc2c1CCN(C(=O)c1cc(C)oc1C)CC2 +CCC(=O)Nc1cccc(OCC(=O)NC2CCCCC2)c1 +Cc1ccc(OCc2noc(C3CC3)n2)c(CO)c1 +CCC(NC(=O)NCCN1CCOCC1)c1ccc(OC)cc1 +Cc1ccccc1C(=O)Nc1ccccc1-n1ncc2c(=O)[nH]cnc21 +O=C(c1cc2ccccc2oc1=O)N1CCN(c2ncccn2)CC1 +CC(C)(C)C(=O)N1CCCC1C(=O)c1ccc(F)cc1 +Cc1nnc(SCCCOC(C)C)c(C#N)c1C +CCNC(=O)c1cccc(NC(=O)c2ccc(C)cc2)c1 +O=C(Nc1nc2cc3c(cc2s1)OCCO3)c1ccccn1 +Cn1c(C(C)(C)C)nc2cc(NC(=O)c3n[nH]c4c3CCC4)ccc21 +O=C(Cc1noc(CCC2CCCO2)n1)Nc1ccccc1Cl +CCC(CCO)CNC(=O)Nc1cc(-c2ncco2)ccc1C +Cn1c(=O)ccn(CC(=O)Nc2cc(C3CCCCCC3)[nH]n2)c1=O +O=C(OCC1CCCC1)c1cccc(OCC(F)F)n1 +O=C(CNCc1cccc(F)c1)Nc1ccc(F)cc1 +COc1ccccc1CC(=O)Nc1cccc(O)c1 +COCc1noc(CCNC(=O)c2cc(-c3ccc(O)cc3)n[nH]2)n1 +Cc1ccc(S(=O)(=O)c2nc(C)cc(C)c2S(C)(=O)=O)cc1 +CC(=O)c1cccc(OCc2cc(C(=O)N(C)CCO)no2)c1 +O=C(Cn1nnc(-c2ccccc2Cl)n1)NCc1ccccc1 +Oc1n[nH]c(C(F)(F)F)c1Cc1ccccc1F +O=S(=O)(NCc1ccccc1F)c1cccc(Cl)c1 +Cc1n[nH]c(C)c1NS(=O)(=O)c1ccc(-c2ccccc2)cc1 +Cc1ccoc1C(=O)NCc1ccc(CN2CC(C)OC(C)C2)cc1 +CC1CCCN(C(=O)CN(CCO)c2cccc(F)c2)C1 +COc1cc(NC(C)=O)ccc1NC(C)c1cnn(C(C)C)c1 +Cc1nc(-c2cccc(NC(=O)CCOC(C)C)c2)oc1C +O=C(NCc1cccs1)C1CCN(C(=O)C2CC3CCC2C3)CC1 +CC(c1ccncc1)N(C)C(=O)Cn1c(=O)n(C)c2ccccc21 +CC(=O)c1cc(Br)cc2c1OCCC(=O)N2C +Cc1sc2ncn(CC(=O)Nc3ccccc3)c(=O)c2c1C +CC(C(=O)N1CCSc2ccccc21)N1CCOCC1 +CC(=O)Nc1ccc(NC(=O)CNC(=O)c2ccc(F)cc2)cc1 +COc1ccc(OC)c(NC(=O)NC(C)C(C)CO)c1 +CC(C)(C)C(=O)COC(=O)c1c[nH]c2ccccc12 +CCCCn1nnc(NC(=O)c2cccs2)n1 +Cc1cc2cc(NC(=O)C3(C)CC3(Cl)Cl)ccc2[nH]1 +CC(=O)NCc1ccc(C(=O)COC(=O)c2ccc(C#N)cc2)o1 +COc1ccccc1OCC(=O)N1CCN(CC(C)O)CC1 +COCc1cccc(-c2nc3sc4c(c3c(=O)[nH]2)CCC4)c1 +CCOc1cccc(NC(=O)C(C)NC(N)=O)c1 +Cc1ccc(OCC(=O)NCCn2nc3ccccn3c2=O)cc1 +Cc1ccc(S(=O)(=O)N2CCCCCC2)c(N)c1 +COCC(O)CN(C)C(=O)c1cc(F)cc(F)c1 +CC(C)CC(=O)NC(C(=O)Oc1ccc2c(c1)CCC(=O)N2)C(C)C +O=C(Nc1cnn(C2CCOC2)c1)c1ccsc1 +C=CCNS(=O)(=O)c1cc(C(=O)Nc2cnn(C)c2)ccc1F +CC(C)CC(=O)NCCc1nc(-c2ccccc2)no1 +Nc1ccc(=O)n(CC(=O)Nc2ccc(Cl)c(Cl)c2)c1 +CC(=O)N1CCC(c2csc(Nc3cnccn3)n2)CC1 +Cc1cccc(C)c1OCC(=O)N(C)Cc1ccc2c(c1)OCO2 +CCC(C)C(NC(=O)c1ccc(NC(=O)C2CC2)cc1)C(N)=O +O=C1CC(c2ccccc2)N(CCc2ccncc2)CCN1 +O=C(NC1CCCC1)c1cnc2scc(-c3ccccc3)n2c1=O +Cc1cc(S(=O)(=O)NCc2cccnc2)ccc1Br +COC1CCN(C(=O)c2ccc(Br)cc2)CC1 +CCCCS(=O)(=O)NC(C#N)c1ccncc1 +CCCn1nc(C)cc1NC(=O)c1ccc(C)c(C)c1 +CCN(C(=O)c1ccc(F)c(COC)c1)C1CCCCC1C +COCCCC(=O)NC1CCN(c2c(F)cccc2F)C1 +CCCn1c(SC(C(=O)NC2CCCC2)C(C)C)n[nH]c1=O +COc1cccc2cc(C(=O)Nc3ccc(-n4cnnn4)c(C)c3)oc12 +Fc1cc(F)c2c(c1)CCNC2c1cc(Cl)ccn1 +CCS(=O)(=O)N1CCN(Cc2n[nH]c(=O)[nH]2)CC1 +CC(C)(NC(=O)Cc1ccc(-n2cccn2)cc1)c1cccc(F)c1 +O=C(CSc1nnc(-c2ccccc2F)o1)NCC1CCCO1 +COCCCNC(=O)c1cc2cc3ccc(C)cc3nc2s1 +Cc1c(Br)c(C(=O)Nc2nc3ccccc3n2C)nn1C +Cc1ccc(C(=O)CCC(=O)N2CC(C)OC(C)C2)s1 +CC(=O)NCc1ccc(-c2csc(-c3sccc3C)n2)o1 +CCCCn1ncc(-c2ccc(OC)c(F)c2)c(C#N)c1=O +CC(Cn1cccn1)NC(=O)c1cc(C(C)C)n(C(C)(C)C)n1 +NS(=O)(=O)c1ccc(OCCOC(=O)C2CCCO2)cc1 +Cc1ccc(SCC(=O)Nc2c(C)n[nH]c2C)cc1 +CCN(Cc1cccc(C)c1)C(=O)C1CCOCC1 +CCN(CC)C(=O)c1ccc(C(=O)Nc2cc(OC)ccc2F)cc1 +Cn1cnc(CNC(=O)c2ccccc2NC(=O)OC(C)(C)C)n1 +CC(CO)NC(=O)c1cc2c(s1)CCC(C(C)(C)C)C2 +Cc1cccc(C(=O)Nc2ccc3[nH]c(=O)sc3c2)c1 +CCN1CCN(C(=O)C2(c3ccc(C)cc3)CCOCC2)CC1 +Cc1cccc(SC(C)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1 +COc1ccc(Br)cc1CC(C)(C)O +O=c1[nH]c(SCc2ccncc2)nc2c1CCC2 +COC(=O)CNc1nccc2c(N)cc(Cl)cc12 +O=C(CCC(=O)c1ccc(Br)cc1)NC1CCCC1 +Cc1nc(-c2ncccn2)sc1C(=O)NCc1ccc(C)n1C +O=C(NCC1Cc2ccccc21)NC1CCOC(c2ccccc2)C1 +O=C(NC1CCCN(c2ccccc2F)C1=O)C1CCOCC1 +CCNC(=O)c1ccc(OCc2ccc(F)cc2)c(N)c1 +Cc1cc(C(=O)N(C)C(C)c2cc(F)ccc2F)c(C)o1 +CNC(=O)NCC(=O)N(CCO)Cc1ccccc1 +Cc1ccc(-c2nc(C(=O)N3CCCCC3)cs2)s1 +Cc1nc(C)c(CC(=O)Nc2ccccn2)c(=O)[nH]1 +COc1ccc(F)c(NCC(=O)NC(C)(C#N)C2CC2)c1 +CC(O)CC(C)CNC(=O)c1cccc(Oc2cnccn2)c1 +Cc1ccc(C)c2c(=O)cc(CNCc3cc(=O)[nH]cn3)[nH]c12 +CCN1CCN(CCCOc2ccccc2F)C(=O)C1=O +CC(=O)Nc1ccc(CNc2ccn(-c3ncccc3Cl)n2)cc1 +COc1ncccc1N(C)C(=O)c1ccc(OCC(F)F)nc1 +Cc1cc(NC(=O)CNc2ccc(C)c(Cl)c2)n(C)n1 +CC1(NC(=O)Cc2cn3ccccc3n2)Cc2ccccc2C1 +COc1cc(NC(=O)Cn2nnc3ccccc32)ncn1 +O=C(NCCCNC(=O)c1ccco1)c1cnc2ccoc2c1 +Cc1ccc2c(C)c(C(=O)N3CC(c4cccnc4)C3)oc2c1 +COC(=O)c1cccc(C(=O)N(C)CCC(F)(F)F)c1 +COc1cccc(C(=O)Nc2nnc(-c3cccc(OC)c3)o2)c1 +O=C(Nc1ccccn1)N1CCCC1C1CCCC1 +CCCCOc1ccc(C)cc1S(=O)(=O)Nc1cccnc1 +CCOc1ccccc1OCC=CCn1ccnc1 +CCOC(=O)CC1C(=O)n2ncc(C#N)c2N=C1C +CNC(=O)Cc1ccc(NC(C)C(=O)N(C(C)C)C(C)C)cc1 +CCC(CC)c1nnc(NC(=O)c2ccc(-n3cncn3)nc2)s1 +CCn1c(C)nnc1SCC(=O)NCc1ccc(C)cc1 +O=C(CCc1ccccc1F)Nc1nnc(C(F)F)s1 +CC(C)(CNC(=O)C1(N2CCOCC2)CCC1)N1CCOCC1 +O=C1CCCc2occ(C(=O)N3CCc4[nH]nc(C5CCC5)c4C3)c21 +COc1ccc2oc(C)c(C(=O)NC3CCCc4c3cnn4C)c2c1 +Cc1ccc2cnn(CCC(=O)NCCc3c[nH]c4ccccc34)c2c1 +CCOc1ccc(N(C)C(=O)c2cccc(-c3nnc(C)o3)c2)cc1 +CCOc1cc(CNC(=O)CC#N)cc(Cl)c1O +CC(=O)Nc1ccc(OC(=O)Nc2ccccc2Cl)cc1 +NC(=O)c1ccc(NC(=O)Cc2cc(-c3ccccc3F)on2)cc1 +CS(=O)(=O)c1nc(C(=O)N2CCCCC2)c2ccccn12 +CNC(=O)c1ccc(Cl)c(NCc2ccc(F)cc2F)c1 +CCC(C)CNc1ccccc1CN(CC)C(C)=O +C=CCN(CC=C)C(=O)c1cc(C)nc2c1c(C)nn2C +O=C(NC1CCCC1)c1cccn1-c1nnc(N2CCCC2)s1 +COCc1ccc(C(=O)N2CCN(c3nc(C)cs3)CC2)o1 +Cc1ccc(NC(=O)c2c(Br)cnn2C)cc1 +Cc1cc(Cl)ccc1NC(=O)C1CCCN(C(=O)c2ccoc2)C1 +Cn1nc(C(=O)NC2CC2)c(=O)c2cc(F)ccc21 +CN(C)C(=O)COc1cccc(NC(=O)NCc2ccncc2)c1 +O=C(CCC(=O)N1CCCCCC1)Nc1nccs1 +C=CCn1c(SC2CCCCNC2=O)nnc1-c1ccoc1C +Cc1cc(C)cc(CCNC(=O)N2CCOC(C(N)=O)C2)c1 +CCOc1ccc(N2CCN(C(=O)c3cccs3)C(C)C2=O)cc1 +O=C(Cc1ccc[nH]1)Nc1cccc(S(=O)(=O)N2CCCCC2)c1 +CCCc1nc(NC2CCN(C(=O)NCC)CC2)c2cnn(C)c2n1 +O=C(Nc1cccc(N2CCCC2=O)c1)c1cccc(-n2cnnn2)c1 +CCN(CC)C(=O)CSc1ccc(-c2ccccc2)nn1 +Cc1noc(C)c1CCNC(=O)NCC1CN2CCCCC2CO1 +CCOc1ccccc1OCC(=O)Nc1cc(F)c(F)c(F)c1 +Cc1ccccc1C1(CNc2nnc(C)c(C)c2C#N)CCOCC1 +Cc1ccc(C(=O)c2c(C)[nH]c3ccc(F)cc23)cc1 +O=C(Nc1ccc(-c2nccs2)cc1)c1cnccn1 +CNC(=O)c1cccc(NCC(=O)Nc2ccccc2C(C)C)c1C +COc1ccc(F)cc1C(=O)NCc1nnc2n1CCCCC2 +N#CCCN(Cc1ccc(Cl)cc1)Cc1ccco1 +Cn1cc(C#N)cc1-c1nc(C2CC2)nn1CCc1ccccc1 +c1ccc(CCSc2nnnn2C2CCOCC2)nc1 +COc1cccc(C(O)CNC(=O)CC(C)(C)c2ccccc2)c1 +CC1C(=O)Nc2c1cc(F)cc2C(O)c1ccccc1F +Cn1cccc1C(=O)NCCSc1nccn1C +CC1CCCN(C(=O)c2c[nH]c3cccc(F)c23)C1 +O=C(CO)Nc1nc2c(F)c(F)c(F)cc2s1 +O=C(NCCc1nc(-c2cccc(Cl)c2)no1)c1ccc(=O)[nH]c1 +COCCN(CC(C)C)C(=O)c1ccc(F)c(NC(C)=O)c1 +O=C1CN(Cc2cc(-c3cccs3)on2)CCN1 +c1cc(CN2CCOC3CCCCC32)cc(-c2ccncc2)c1 +CC(C)n1nnnc1SCC(=O)Nc1ccc2c(c1)OCCO2 +NC(=O)Nc1ccc(CNC(=O)c2c[nH]c3ccccc3c2=O)cc1 +CCCN1C(=O)NC(c2ccccn2)C(C(=O)OC)=C1CC +COC(=O)C(NS(=O)(=O)c1ccccc1OC)C(C)C +Cc1ccc(CNC(=O)c2ccc3nncn3c2)c(OCC2CC2)c1 +CC(C)N(CC(N)=O)C(=O)C1(C#N)CCCCC1 +Cc1cccc(C(=O)N2CCCC2c2cc(C)on2)c1 +Cc1cccc(CN(Cc2ccccn2)Cc2cc(C#N)cs2)c1 +Cc1ccc(S(=O)(=O)CNC(=O)OC(C)(C)C)cc1 +CCOc1ccc(OC(=O)Cc2ccc(NC(C)=O)cc2)cc1 +CC(=O)NC(C(=O)NCC(=O)N1CCCC1)C1CCCC1 +O=c1[nH]c(CNc2ccc3cc[nH]c3n2)nc2ccccc12 +CCC(=O)Nc1ccc2c(c1)nc1n2CCN(Cc2ccccc2)C1 +COc1cccc(Cc2nnc(NC(=O)c3cccc(C)n3)s2)c1 +COc1ccc2ncc(NC(=O)NCc3ccco3)c(O)c2n1 +NC(=O)c1ccc(C2CN(Cc3ccc4cc[nH]c4c3)CCO2)nc1 +CCOc1c(O)ccc2c1C(C=Cc1ccco1)NCC2 +COc1cc(NC(=O)c2ccco2)c(OC)cc1Cl +O=C(COC(=O)C1C2CC3OC(=O)C1C3C2)Nc1ccccc1Cl +Cc1[nH]nc(C(=O)Nc2ccc(F)cc2F)c1N +Cc1[nH]c(=O)nc(N)c1-c1cccc(Br)c1 +CCN(CC)C(=O)Cc1ccc(Cl)c(Cl)c1 +Cc1ccc(S(=O)(=O)NC2CNC(=O)C2)cc1C +Cc1ccnc(NC(=O)CNC(=O)c2ccc(F)cc2)c1 +CC1CCN(C)c2ccccc2N1C(=O)CCn1cccn1 +NC(=O)C1CCN(C(=O)c2csc(-c3ccsc3)n2)C1 +CCCCN(C)S(=O)(=O)N(C)c1ccccc1C(N)=O +COc1cc(OC)nc(-c2ccnc3c2ccn3C)n1 +CCNC(=O)CNC(=O)CSc1nc2ccccc2n1C +Cn1c(=O)n(CC(=O)Nc2cccc(F)c2)c2ccccc21 +Cc1ccc(NC(=O)Cn2c(=O)oc3ccccc32)c(O)c1 +CCCn1c(C)nnc1SCC(=O)NCc1ccccc1 +COc1cc(-c2noc(-c3csc(-c4cccs4)n3)n2)ccn1 +Cc1nc(Nc2cnccn2)cc(C2CCN(c3ncccn3)C2)n1 +COCCNc1ccc(CNC(=O)Nc2ccc(C#N)cc2)cc1 +Cc1ccccc1C(=O)N1CCN(C(=O)CC(F)(F)F)CC1 +COCC(=O)NC(C(=O)N1CCCC(C(C)(C)C)CC1)C(C)C +CCc1nc(CNc2ccc(N3CCCC3=O)cc2)cs1 +Cc1ccc(S(=O)(=O)NC2CC(=O)N(c3ccccc3)C2)cc1C +Cc1noc(Cc2ccccc2NC(=O)COc2ccccc2)n1 +Cn1c(=O)oc2cc(NC(=O)NCc3ccccn3)ccc21 +O=C(CSc1ccc(-c2cccnc2)nn1)Nc1ccccc1 +Cc1cc2cccc(C(=O)N(C)Cc3cnn(-c4ccccc4)c3)c2o1 +O=C(Nc1nccs1)c1cc(F)c(F)cc1Cl +CC(C)NC(=O)c1ccc(NC(=O)C(C)NC(N)=O)cc1 +O=C(CN1CCOCC1C1CC1)Nc1ccc(Br)cc1 +Cc1cc(CN2CCN(C(=O)c3cc(F)cc(F)c3)CC2)no1 +COC1CCCC1OC(=O)CNC(=O)CC1CCCCC1 +Cc1ccc(N(CCC#N)C(=O)Cn2cnnn2)cc1C +COC1CCN(C(=O)CCc2cccc(N)c2)CC1 +Cc1cccc2nc(C(=O)N3CCc4ccc(O)cc4C3)cn12 +COC(CNS(=O)(=O)Cc1cccc(C)c1)c1ccccc1C +CN(C(=O)c1ccc(-n2ccnn2)cc1)c1ccccc1F +Cc1nc(-c2ccc(NC(=O)NCCCn3cccn3)cc2)cs1 +C=CCNC1=NS(=O)(=O)c2c(Cl)cc(Cl)cc2N1 +Cc1cc(CNC(=O)NC(C)c2nnc3ccccn23)ccc1F +CCNS(=O)(=O)c1cc(C)c(OCC)cc1C +Cc1ccnc(NC(=O)c2ccc(C)c(NS(C)(=O)=O)c2)c1 +COc1cc2c(cc1OC)-c1c(c(C(=O)NCCCO)nn1C)C2 +Cc1ccc(C(=O)NCC2(c3ccc(F)cc3F)CC2)nc1 +O=C(Nc1cc(Cl)cc(Br)c1O)C1CCCOC1 +COc1ccc(NC(=O)c2cc(-c3cccnc3)on2)cc1OC +Cc1ccc(C(=O)N2Cc3ccccc3CC2C(N)=O)cc1 +CC(NS(=O)(=O)c1ccc(F)cc1)c1ccc2c(c1)OCO2 +Cc1noc(C)c1CC(=O)Nc1ccc(Cl)cc1F +COc1cc2nc3n(c(=O)c2cc1OC)CCN(C(=O)C1CC1)CC3 +Cc1sc2ncn(CC(=O)NC(C)c3cccnc3)c(=O)c2c1C +CC(C)n1nccc1NC(=O)c1ccc(O)c(Cl)c1 +O=C1OCCN1Cc1ncnn1Cc1c(F)cccc1Cl +CNC(=O)Cn1cc(NC(=O)CCc2c(C)noc2C)cn1 +CNC(=O)C1CN(C(=O)CCCc2ccccc2)c2ccccc2O1 +Cc1ccc(NC(=O)CNc2ccc(C(=O)N(C)C)cc2)cc1Cl +CCc1ccc(Oc2ncnc(NCC3CCCO3)c2N)cc1 +CC(=O)N1CCc2cc(NC(=O)CC3C=CCC3)ccc21 +CCn1nc(C(=O)NCCC2=CCCCC2)c2ccccc2c1=O +CNS(=O)(=O)c1ccc(CNC(=O)c2ccoc2)cc1 +Cc1ccc(OCCNC(=O)c2cc(C)oc2C)cc1 +CCCNC(=O)Cn1c(C)c(C)c2c(N)ncnc21 +O=C1CC(C(=O)NCCNC(=O)c2ccccc2)CN1 +CC1(C)CC(=O)c2sc(NC(=O)Cn3ccc(=O)[nH]c3=O)nc2C1 +CCn1cc(NC(=O)NCc2cccc(S(=O)(=O)NC)c2)cn1 +C=CCNC(=O)NCc1cccc(OCC(F)(F)F)c1 +Cc1csc(CNC(=O)Cn2cc(Br)ccc2=O)n1 +C#CCN1CCN(C(=O)NCC2CCN(c3ccc(F)cc3)C2)CC1 +Nc1cccc(C(=O)Nc2ccc(Cl)cc2C(F)(F)F)c1 +COc1cc(NC(=O)c2ccccc2)ccc1-n1cnnn1 +CN(C)S(=O)(=O)c1ccc(F)c(C(=O)NCc2ccco2)c1 +C=CCn1c(C(C)NC(=O)C2CC2)nc2ccccc21 +Cc1nc2ccccc2n1CCNC(=O)C1CCCc2ccccc21 +CCC(=O)c1ccc(OC(=O)c2ccc(C)nc2)cc1 +O=C(NCCCc1nc2ccccc2[nH]1)c1cc(F)cc(F)c1 +COC(=O)c1ccc(C)c(NC(=O)c2cccnc2SC)c1 +COCCN(Cc1ccsc1)C(=O)c1cnc(C)c(C)c1 +CN(CCOc1ccccc1)C(=O)c1cccc2cccnc12 +COc1ccc(-c2cc(C(C)C)nc(C)n2)c(OC)c1 +Cc1c(C)c(C)c(S(=O)(=O)NCCN2CCOCC2)c(C)c1C +CC(C)C(=O)N1CCN(c2cc(N3CCCCC3)ncn2)CC1 +CC(C)c1nccc(NC2CCCN(C(N)=O)C2)n1 +CCOc1cc(C#N)ccc1OCC(=O)NCc1ccccc1F +NC(=O)CCCNC(=O)c1cc2c(s1)CCCCC2 +Cc1sc2ncn3c(=O)n(CC(=O)N4CCOCC4)nc3c2c1C +Cc1cccc2c(CCNC(=O)c3ccc(-n4ccnn4)cc3)c[nH]c12 +Cn1c(=O)c2ccn(CC(=O)Nc3ccccn3)c2n(C)c1=O +O=C(CCc1ccsc1)N1CCCN(c2cccnn2)CC1 +CCOc1ccc(-c2nc(C)c(C(=O)NCC(C)O)s2)cc1 +COC(=O)c1cccc(-c2nc(-c3cn(-c4ccccc4)nn3)no2)c1 +CC(=O)Nc1cccc(-n2nnnc2SCCn2cccn2)c1 +N#Cc1ccc(NC(=O)CCCNC(=O)c2ccc(Cl)cc2)cc1 +CC(=O)NC(C)C1NCCc2ccc3[nH]ccc3c21 +CC(C)c1ccc(OCc2nc(CN)cc(=O)[nH]2)cc1 +O=c1[nH]c(=O)n(COCc2ccccc2)c2ccsc12 +CCCOc1ccc(NC(=O)N(C)CCC#N)c(C)c1 +O=C(CSc1cnnc(O)n1)Nc1c(Cl)cccc1Cl +NC(=O)c1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 +Cc1nnsc1C(=O)NCc1ccc(C(=O)c2ccccc2)s1 +CC(C)N(Cc1ccccc1)C(=O)Cn1cnc(C#N)n1 +CCC(NC(C)C(=O)NCc1ccco1)c1ccccc1 +O=C(CCC1CCCCC1)N1CCN(Cc2nc(C3CC3)n[nH]2)CC1 +Cc1c(N)cc(C(=O)NCC2CCCCC2)cc1F +NC(=O)c1ccc(Cl)cc1NC(=O)c1ccc2c(c1)OCCO2 +CCCNC(=O)c1ccccc1NC(=O)CCc1ccccc1 +CCC(=O)Nc1cccc(NCc2c(C)nc3sc(C)cn23)c1 +CCc1nc(N2CCC(C)CC2)sc1C(C)=O +COc1ccc(N(C)C(=O)CCn2cc(C)cn2)cn1 +Cc1c(O)cc2c(c1O)C(=O)CC(c1ccc(O)cc1)O2 +CC(C)N1CC(C(=O)NCC(C)N2CCc3ccccc32)CC1=O +Cc1noc(NC(=O)c2ccn(-c3ccc(F)cc3)n2)n1 +O=C(Nc1cccc(F)c1)c1ncc2ccccn12 +O=C(Cc1ccc(F)cc1)N1CCN(C2CCCC2O)CC1 +CCOCC1(CNC(=O)Nc2ccccc2Cl)CCC1 +N#Cc1ccc(CNc2cnc3ccccc3n2)cc1 +C=CCCC1NCCc2c(OC)cc(Br)cc21 +CC(=O)NCCC(=O)OC(C)C(=O)Nc1cccc(Cl)c1Cl +O=C1CN(C(=O)c2ccc(F)cc2F)c2ccccc2N1 +CN(CC(=O)NC(C)(C)C)C(=O)C1(C)COC(C)(C)OC1 +CN(C)C(=O)C1CCCN(c2cccc(F)c2C#N)C1 +Cc1ccc(S(=O)(=O)NC(=O)OC(C)(C)C)cc1 +CNS(=O)(=O)C1CCOCC1Cc1ccc(OC)cc1 +COc1cc(C(=O)Nc2ccccc2)cc(Cl)c1OCC(N)=O +O=C(c1cccc2cn[nH]c12)N1CCc2ccccc2C1 +CCc1ccccc1NC(=O)CSc1nc2nc(C)cc(C)n2n1 +Cc1nc2cc(NC(=O)c3ccc(-c4cnccn4)cc3)ccc2n1C +CS(=O)(=O)c1ccc(NC(=O)c2cc(N)c[nH]2)cc1 +CCCCN1CCc2ccc(NC(=O)CNC(=O)NC)cc21 +O=C(COc1ccccc1F)NCc1cccc(Cl)c1 +CCc1nnc(NC(=O)NCc2ncoc2C)s1 +Cc1cnn(CC2CN(CC(=O)Nc3nnc(C)s3)CCO2)c1 +CC(=O)N1CC(=O)Nc2ccc(C)cc2C1c1ccccc1 +Cc1ccc(-n2c(C)c(C)n3c4c(=O)[nH]c(=O)n(C)c4nc23)cc1 +COCCN(C)C(=O)NCCc1coc(-c2ccc(C)cc2)n1 +CC1(O)CCN(C(=O)Cn2cc(C(F)(F)F)ccc2=O)CC1O +COc1cc(F)c(F)c(F)c1C1(C)COCCN1 +CCNc1nnc(SCCC(=O)Nc2ccccc2C#N)s1 +CNC(=O)c1cccc(CNC(=O)NCCCOC)c1 +CC(NCC(O)c1ccc(F)c(F)c1)c1ccco1 +Nc1cccc(N2CCN(C(=O)Cc3cccs3)CC2)c1 +N#Cc1cccc(NC(=O)CCCCC(=O)Nc2cccc(C#N)c2)c1 +CCCC(NC(N)=O)C(=O)Nc1ccc(C(F)(F)F)cc1 +CC(C(=O)NCc1ccccc1)n1nc(-c2ccccc2)ccc1=O +O=C(CCC1CCCC1)N1CCN(Cc2cc3ccccn3n2)CC1 +O=C(OCc1csc(-c2ccccn2)n1)c1n[nH]c2ccccc12 +Cc1ccc(-n2nnnc2N(C)Cc2nnc3ccccn23)cc1 +O=C1CC(c2ccccc2Cl)c2c(c3ccccc3[nH]c2=O)O1 +Cc1nnc(NC(=O)CCn2c(=O)sc3ccccc32)s1 +CSc1nnc(-c2c[nH]c3ccccc23)n1CC1CCCO1 +COC(=O)CSc1nnc(-c2cccnc2)n1C +CN(C)c1ccc(C#CCNC(=O)C2CCCC2)cc1 +Cc1csc(CNC(=O)c2ccc(CN3CCCC3=O)cc2)n1 +COc1cc2cc(CCC#N)c(=O)[nH]c2cc1OC +CCN(Cc1cccc(F)c1)C(=O)c1ccc(-n2ccnn2)cc1 +CCC(=O)Nc1sc(C(=O)Nc2ccccc2)c(C)c1C(=O)OC +COc1cccc(C=C(NC(C)=O)c2nc3cc(Cl)ccc3[nH]2)c1 +CN(C)c1nc(COc2ccccc2CO)ns1 +CN(Cc1ccncc1)C(=O)Nc1ccccc1N1CCCC1=O +CCc1cccc(NC(=O)COc2ccc(C(C)=O)cc2OC)c1 +Cc1[nH]ncc1S(=O)(=O)Nc1ccc(F)cc1 +CCn1c(C)cc(C(=O)Nc2ccc(F)c(NC(C)=O)c2)c1C +Cc1ccc(NC(=O)Cn2cnc3ccc(Cl)cc3c2=O)c(C)c1 +O=C(NCc1noc(-c2ccco2)n1)c1ccc2ccccc2n1 +N#CCSc1nnc(-c2ccco2)n1Cc1ccccc1 +C=CCOc1ccccc1C(=O)Nc1cccc(C)n1 +CN(C(=O)CSc1nnc(C2CC2)n1C)c1nccs1 +CC1(C)Cc2cccc(OCCNC(=O)c3ccc[nH]c3=O)c2O1 +Cn1nccc1-c1nn2c(C(F)F)nnc2s1 +CCCn1nc(C(=O)NC(C)c2cc(C)sc2C)ccc1=O +O=C(Nc1ccc(Br)cc1)c1ccc(=O)[nH]c1 +CN(C(=O)C1(C#N)CCCC1)c1ccc(F)c(F)c1 +N#Cc1ncn(CC(=O)Nc2cc(Cl)ccc2-n2cncn2)n1 +CCC(C(=O)Nc1cccnc1)N(c1ccccc1)S(C)(=O)=O +CCOc1ccccc1CCNC(=O)NCc1ncn(C)n1 +CC1CN(C(=O)c2ccc(NCc3ccccc3C#N)cc2)CC(C)O1 +N#Cc1nc(C2CC2)oc1N1CCN(S(N)(=O)=O)CC1 +Cc1c(C)n(-c2ccccn2)c2ncnc(NCc3ccccc3)c12 +N#CCc1cccc(C(=O)NC(Cc2ccccc2)C(=O)NC2CC2)c1 +c1ccc(Cn2nnnc2CN2CCc3sccc3C2)cc1 +Cc1cc(C)cc(C(N)C(=O)NCc2ccccn2)c1 +Cc1cc(C)c(NC(=O)CN(C)C(=O)c2cccs2)c(C)c1 +COc1c(CN2CCN(C(C)c3ccccn3)CC2)c(C)nn1C +O=C(Nn1cnc2oc(-c3ccccc3)cc2c1=O)c1ccccc1 +C=C1C2(C(=O)NCc3ccco3)CCC(C2)C1(C)C +COc1ccc(CN(C)C(=O)c2c(C)noc2C)cc1OC +O=c1oc2c(c(O)nn2-c2ccccc2)c2c1CCCC2 +CCN(CC)C(=O)N1CCC(C(=O)Nc2cc(C)ccc2C)CC1 +CCC(C)(C)OCC(O)CN1CCN(c2ccccc2F)CC1 +O=C(Nc1ccccc1OCC1CCCO1)c1ccco1 +Cc1ccc(C2CC2C(=O)N2CCOCC2C2CC2)s1 +CC(=O)Oc1ccc(C(=O)NCc2ccc(C)cc2)cc1 +CCC(=O)Nc1ccc(NC(=O)Cc2ccccn2)cc1Cl +CN(CCCNC(=O)C1CCC(=O)N1)S(C)(=O)=O +Fc1ccccc1CNCC(c1ccccc1)N1CCOCC1 +Cc1ccc(N2CC(C(=O)NCC(C)C)CC2=O)cc1C +Cc1ccc(CN(Cc2ccco2)C(=O)COc2ccccc2)o1 +CCN1CCN(C(=O)c2cc(C)nc3c2cnn3C2CCCC2)CC1 +CCNC(=O)CSc1nnnn1-c1ccccc1C +CCOC(=O)CNc1ccc(Br)cn1 +Cn1cc(C(=O)NCc2ccccc2Cn2cccn2)ccc1=O +CCCN(CC(=O)NC)C(=O)c1cnc2ccc(C)cn12 +Cc1nc(-c2ccncc2)ncc1C(C)Nc1cnc2ccccc2n1 +CC(C)N(C)C(=O)NCc1ccccc1S(=O)(=O)N(C)C +O=C(CSc1nnc(NC2CC2)s1)Nc1ccc(F)cc1F +Cc1onc(-c2cccnc2)c1C(=O)NC1CCCOC1 +CCCOc1cc(C)ccc1NCc1nsc(N(C)C)n1 +O=C(Nc1cc(Cl)ccn1)c1ccc(Br)cc1 +CCCCNS(=O)(=O)c1cnc(NC(C)C)c(C)c1 +CCc1nc2c(=O)n(CC(=O)NCCC(C)C)nc(C)c2s1 +CCC(CC)NC(=O)C1CC(=O)N(c2cccc3ccccc23)C1 +CN1C(=O)CSc2cnn(CC(=O)NCc3ccccc3)c(=O)c21 +CC(CCCO)NC(=O)Nc1cccc(C(=O)NC(C)(C)C)c1 +CC(C)c1nncn1CCNC(=O)Cn1c(=O)[nH]c2ccccc21 +CC(C)Oc1ccc(C#N)cc1NC(=O)C1CC1C +CCN(Cc1cccc(F)c1)C(=O)c1ccc[nH]c1=O +Cc1ccc(Cn2c(=O)c3c(nc4oc(C)c(C)n43)n(C)c2=O)cc1 +CCC1=C(C(=O)OC)C(c2cccc(O)c2)n2ncnc2N1 +CCc1nnc2n1CC(Nc1cnc3ccccc3n1)CC2 +Cc1cnc2c(c1)N(S(=O)(=O)c1ccc(C#N)nc1)CCO2 +COC(=O)Cn1ccnc1-c1c(OC)cccc1OC +COc1cc(=O)c(C(=O)NC2CC2)nn1-c1ccc(F)c(F)c1 +CN(CC(=O)NC1C2CCOC2C1(C)C)C(=O)c1ccccc1 +Cn1ncc2c(C(F)F)cc(-c3cccs3)nc21 +O=C(CCn1ncc2ccc(Cl)cc21)NCc1ccccc1F +Cc1cc(NC(=O)c2cccc(Br)c2)[nH]n1 +CC(=O)Nc1cccc(OCCCNC(=O)c2ccc(Cl)cc2)c1 +Cc1cc(C)cc(CC2Oc3cc(N)ccc3N(CCO)C2=O)c1 +COC1CCC(CC(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)CC1 +COc1ccc(Cn2cc(Br)cn2)cc1OC +Cc1c(NCc2noc(-c3ccoc3)n2)cccc1N1CCOC1=O +Cc1noc(C)c1CC(=O)Nc1ccc(C(C)C)cc1 +CCOc1ccc(-n2nnc(C(=O)NCC3CCCO3)c2C)cc1 +Cc1cc(NC(=O)COc2ccc(Cl)c(C)c2)[nH]n1 +CCOc1cc(NC2CCCCC2C)nc(COC)n1 +Cn1cc(NC(=O)Nc2ccc3c(c2)CCC3)cn1 +Cc1noc2ncc(-c3nnc(-c4ccc(F)cc4)o3)cc12 +NC(=O)C(NC(=O)C1COc2ccc(F)cc2C1)c1ccccc1 +CCN(CC(=O)NC1CCCCC1)S(=O)(=O)c1ccc(F)cc1 +COc1cc(C)c(C(=O)OC(C)c2nccs2)cc1OC +COc1ccc(CCNC(=O)c2cc3ccncc3cn2)cc1OC +CCOc1cc(F)ccc1NCC(=O)NCC(F)(F)F +CCOC(=O)c1cc(C(=O)Nc2ccccc2CC)nn1C +Cc1nc2ccc(C(=O)NCC(C)N3CCOCC3)cc2s1 +CC(C)Cc1cc(-c2nnc3sc(C4CCC4)nn23)n(C)n1 +Cc1cnc(COc2ccc3c(C(C)C)cc(=O)oc3c2)cn1 +COc1ccccc1CCNC(=O)c1cc(=O)c(OC)cn1C +O=C(CSc1nnc2ccccn12)c1c[nH]c2ccccc12 +CCOc1ccc(C(O)CCCC(=O)N(C)C)cc1 +Cc1cc(C)n(CCCC(=O)Nc2ccc(C#N)cc2)n1 +COCCn1nc(C)c(NC(=O)C2C(C=C(C)C)C2(C)C)c1C +CC(C)c1nc(C2CCCN(C(=O)c3ccc4nccn4c3)C2)no1 +CC(=O)c1ccc(N2CCCC(CO)(Cc3ccccc3C)C2)nc1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)OCc1ccc(C#N)cc1 +O=C(NCCc1cn2ccccc2n1)c1cncc(Br)c1 +Cn1ccnc1COc1ccc(CSc2nncn2C)cc1 +CCN(C(=O)COc1ccc(NC(=O)C(C)C)cc1)C1CC1 +COc1ccc(S(=O)(=O)NCc2cnn3ccccc23)cc1 +COC(=O)c1ccc(OS(=O)(=O)c2ccccc2)cc1 +Cc1cccc(C(C)C)c1NC(=O)C(C)CC(N)=O +O=C(CSc1nnc(NC2CC2)s1)c1ccc(O)cc1 +CC(C)C(C)NC(=O)c1cnn2c(-c3cccc(Cl)c3)ccnc12 +CC1CCCc2sc3nc(NCc4ccco4)n4ncnc4c3c21 +CCOC(=O)C1CCCCN1C(=O)OCc1ccccc1 +CNS(=O)(=O)c1ccc(C(=O)Nc2cc(C)cc(C)c2)o1 +COc1ncccc1CNC(=O)c1ccc(C)nc1 +N#Cc1c(F)cccc1NCc1ccc(C(=O)NCC(N)=O)cc1 +Fc1cc(F)c(CNCc2cccnc2)c(F)c1 +COc1ccc(-n2ncnc2CCNC(=O)c2ccccc2F)cc1 +Cc1cc(C)n(-c2ccc(NC3CCC(=O)N(C)C3)nn2)n1 +CCc1c(C)sc(NC(=O)C2CCCCC2)c1C(N)=O +COc1ccc(-n2cc(CNC(=O)c3ccoc3)nn2)cc1 +Nc1ccc(C(=O)OCC(=O)Nc2ccc3c(c2)OCO3)cc1 +Cc1cc(N2CCCC2=O)ccc1S(=O)(=O)NCC1CCOC1 +COC(=O)c1ccc2[nH]cc(CN3CCOCC3)c2c1 +Cc1ccsc1-c1cc(NC(=O)c2cnn(C)c2)[nH]n1 +O=C(CNC(=O)NCc1ccccc1)NCCc1cccs1 +Cc1cc2[nH]c(SCC(=O)Nc3c(C)cccc3C)nc(=O)c2[nH]1 +CC(NC(=O)NCC(=O)N(C)C)c1ccccc1C(F)(F)F +CCOC1CC(NC(=O)Cc2c[nH]c3ncccc23)C12CCCC2 +CN(C(=O)Nc1cccc(N2CCOC2=O)c1)C1CC1 +CC(C)C1C(=O)NCCN1C(=O)Cc1ccc(-n2cnnn2)cc1 +CCS(=O)(=O)N1CCCC(C(=O)Nc2ccc(F)cc2)C1 +OCCCC(O)c1cc(Br)cs1 +COc1ccc(CC(=O)N(C)c2ccccc2)cc1F +CC(C)S(=O)(=O)NCc1cnn2ccccc12 +Cn1ccc(NC(=O)COc2ccc3c(c2)CCC3)n1 +CN(CCc1ccccn1)c1cnc2ccccc2n1 +COc1ncccc1C(=O)N1CCCC1c1nc(-c2ccccc2)n[nH]1 +COc1ccc(CCNC(C#N)c2cccnc2)cc1 +CC(C)c1csc2nc(Cc3cnoc3)[nH]c(=O)c12 +CC1CCCCN1C(=O)NCc1ccnc(OCC(F)(F)F)c1 +O=C(CSc1ccncc1)N1CC=C(c2ccccc2Cl)CC1 +Cc1nc(S(=O)(=O)c2ccc(F)cc2)c(N2CCCCCC2)o1 +O=C(C1CCCCC1)N1CCC(Oc2nncc3ccccc23)CC1 +Cc1nscc1C(=O)Nc1cccc(Cl)c1 +O=C(CN1CCCC(C(F)(F)F)C1)NCc1ccc2c(c1)OCO2 +CSc1nnc(Cc2cccc(O)c2)c(=O)n1N +Cn1cccc1C(=O)NC1CCS(=O)(=O)c2ccccc21 +CC(C)CNC(=O)COc1ccccc1C(N)=O +CC(C)c1ccc(CN(C)C(=O)c2cccc(S(C)(=O)=O)c2)cc1 +CCOC(=O)N1CCCC(C(=O)NC2CCCc3occc32)C1 +COc1ccc(S(=O)(=O)CC(C)C(=O)OC2CCCCC2)cc1 +N#Cc1ccc(NS(=O)(=O)c2ccccc2C(F)(F)F)cc1 +CC(C)CN(CCC#N)C(=O)CNc1ccccc1 +NC(=O)CC1CCN(C(=O)CCCNc2ncccn2)CC1 +Cc1cc2c(cc1S(=O)(=O)NC1CCCCC1C)OCCN2C +O=C(Nc1ccc(Oc2ccc(F)cc2)nc1)c1ccncc1F +C=CCNC(=O)c1onc(-c2cccc(OC)c2)c1N +Cc1cc(C)c(C(=O)NCC(CO)Cc2cccs2)c(=O)[nH]1 +COc1ccc(S(=O)(=O)Nc2ccccc2C(N)=O)c(OC)c1 +COC(=O)c1c(C)c(C(=O)CN(C(=O)C2CCC2)C2CC2)c(C)n1C +Cc1nnc(-c2cc(NC(=O)c3cccnc3)c(C)s2)o1 +Cc1ccncc1NC(=O)Nc1cccc(COC(C)C)c1 +CC(OC(=O)c1cc(C(N)=O)cs1)c1ccccc1 +CCCOc1ccc(NC(=O)c2cn[nH]c2)cc1Cl +CC(NC(=O)NCCC(=O)N1CCCC1)c1ccc(C(C)(C)C)cc1 +Cc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +O=C(Nc1cc(-c2ccncc2)n[nH]1)c1cnc2sccn2c1=O +CNC(=O)CN1CCN(C(=O)COc2ccccc2Cl)CC1 +Cc1ccc2c(c1)sc1nnc(S(C)(=O)=O)n12 +CCn1cc(CC(=O)N2CCCN(C(N)=O)CC2)c2ccccc21 +O=C(NCCc1ccccc1Cl)c1ccc(-n2ccnn2)cc1 +COC(=O)c1ccn2nc(Cc3ccccc3OC)nc2c1 +COc1ccc(C=C(C)c2cnccn2)cc1C#N +CCc1ccc(S(=O)(=O)Nc2cccc(NC(=O)CO)c2)cc1 +Cc1cnc(CN2CCOC(c3nc(C(C)(C)C)cs3)C2)cn1 +O=C(OCCCc1cccnc1)c1ccn(-c2ccc(F)cc2)n1 +CCn1c(-c2ccccc2C)nnc1S(C)(=O)=O +CC(C)(O)CN1CCN(c2cccc(Cl)c2)CC1 +CC(Oc1cccc(F)c1)C(=O)Nc1ccccc1F +CC(=O)NCc1ccc(C(=O)NC2CC2c2cccc(Cl)c2)cc1 +CCSc1nc2ccccc2c(=O)n1CC(C)C +O=C(NC1CCCC1)c1csc(C(=O)NC2CCCC2)n1 +CN(Cc1ccccc1OC(F)(F)F)C(=O)C1CCC(=O)N1 +CCCc1nc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)cs1 +O=C(NCc1ccccc1)c1cc2c(s1)CCN2C(=O)C1CC1 +CC(O)CNC(=O)c1ccc(OCc2ccccc2C#N)cc1 +CCOCC1CCCN(C(=O)c2cn(C)nc2C)C1 +Cc1cc(S(=O)(=O)Nc2cccnc2)ccc1F +COC(=O)C(NC(=O)N1CCN(c2ncccn2)CC1)C(C)C +CCOC(=O)c1cccc(NC(=O)Cc2noc3ccccc23)c1 +O=C(Cn1ncc2c(Cl)cccc21)N1CCC2(CC1)OCCO2 +Cc1ccc(CN(C)C(=O)CSc2nnc3ccccn23)c(C)c1 +CC1CCN(c2nc(C(C)NC(=O)C3CCCC3)cc(=O)[nH]2)CC1 +CC(C)CC1(CNS(=O)(=O)N(C)C2CCOCC2)CCCC1 +COC(=O)c1ccccc1NC(=O)N1CCC(n2cccc2)CC1 +Cc1ccc2c(c1O)CCNC2c1c(C)ncnc1C +CCOC(=O)CC1CCN(C(=O)NCc2cnc(C)s2)CC1 +COc1ccnc(NC(=O)c2cnc(-c3ccccc3)s2)c1 +Cc1ccc(C(C#N)N(C)C(=O)c2ccccc2)cc1 +CCn1cc(-c2cc(C(F)(F)F)c3c(C4CC4)noc3n2)cn1 +CN(CCOc1ccccc1F)C(=O)Cn1cnc2ccccc21 +O=C(c1nc(-c2cnccn2)no1)N1CCc2ccccc21 +COc1ccc(CNC(=O)NCc2cc3ccccc3o2)c(OC)c1 +O=c1c(=Cc2cccs2)sc2nc(-c3cccs3)nn12 +CCOC(=O)Nc1ccc(NC(=O)N2CCOCC2)cc1 +Cc1noc(C)c1CC(=O)NCC1CCOCC1 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)N1CCCCCC1 +CCN1C(=O)NC(c2cccnc2)C(C(=O)OC)=C1C +C#CCN(Cc1ccc(F)cc1)Cc1cnn(C(C)(C)C)c1 +Cc1oc(C(=O)NCc2ccc(F)c(Cl)c2)cc1S(N)(=O)=O +Cc1ccc(Cl)c(OCc2ccc(C(N)=O)cc2)c1 +CC(C(=O)Nc1ccc(C(=O)N2CCCC2)cc1)c1cccs1 +Cc1nc(C)c(CN2CCN(Cc3nccn3C(F)F)CC2)s1 +CCOC(=O)Nc1nc(CC(=O)N2CCCCCC2)cs1 +N#Cc1c(F)cccc1NCCNC(=O)c1c[nH]c2ncccc12 +COC(=O)CCC(=O)Nc1nc(C2CC2)cs1 +CNC(=O)c1c(NC(=O)c2cccc(OC)c2OC)sc(C)c1C +CC(Sc1nncs1)C(=O)Nc1ccc(N2CCCCC2)nc1 +COc1ccc(CNC(=O)CCc2n[nH]c3ccccc3c2=O)cc1 +Cc1nn(C)c(=O)c(C(=O)Oc2ccccc2Cl)c1C +COc1ccccc1Nc1nc2nonc2n2nnnc12 +CCOC(=O)C(Cc1nc(-c2ccccn2)cs1)NC +COCCC(C)C(=O)N1CCC(OCc2ccccc2F)CC1 +CC(=O)c1ccc(OCc2nc(-c3cccs3)no2)cc1 +O=C(N(c1ccccc1)c1ccccc1)n1ccnc1 +NC(=O)COC(=O)C1CC(=O)N(c2cc(Cl)cc(Cl)c2)C1 +Cc1nc(-c2cccc(C(=O)C(C#N)c3ccccn3)c2)no1 +CCc1nc2n(n1)CCCC2NC(C(=O)OC)c1ccccc1Cl +O=C(Nc1cccc(N2CCCCCC2)c1)c1ccncc1F +CN(CCN(C)C(=O)OC(C)(C)C)C(=O)Nc1cc(F)ccc1F +CC(=O)c1ccc(NC(=O)C2CCN(C(=O)C3CC3)CC2)cc1 +O=C(NCCC1CC2CCC1C2)c1ccccc1-n1cccn1 +Cc1cc(C(=O)N2CCN(Cc3cc(C(N)=O)cs3)CC2)on1 +O=C(NCc1cccc(Cn2ccnc2)c1)NCc1ccco1 +C#CCCN1CCN(C(=O)c2cc(C)nc3onc(C)c23)CC1 +Cc1c(C(N)=O)sc2ncn(CC(=O)c3cccs3)c(=O)c12 +O=C(CNC(=O)c1cc2c([nH]c1=O)CCCC2)OCc1ccccc1 +COCCn1cc(NCc2ccc(C)o2)ccc1=O +Cn1c(N)nnc1SCc1cccc(C(F)(F)F)c1 +COc1cccc(NC(=O)C(C)Sc2nncn2C)c1 +COc1cc(F)ccc1NC(=O)CNC(=O)CC(C)(C)C +Cc1cccc(CNC(=O)CC2CCN(S(C)(=O)=O)CC2)n1 +CNC(=O)Nc1ccnn1Cc1ccc(OC(F)(F)F)cc1 +Nc1c(N)n(CCc2c[nH]c3ccccc23)c(=O)[nH]c1=O +Cc1ccc(-c2ncc(CN3CCN(Cc4ccon4)CC3)s2)o1 +CC(c1ccccc1)n1cnnc1Cc1ccncc1 +CCCNC(=O)c1ccc2c(c1)nnn2Cc1ccccc1 +CC1(C)N=C(N)N=C(N)N1c1ccccc1Cl +Cc1nn(CC(=O)Nc2ccccc2C(=O)C(C)C)c(C)c1Cl +Cc1cccc(C(=O)N(Cc2ccccc2)c2ccccn2)n1 +Cn1c(=O)c2cc(S(C)(=O)=O)nnc2n(C)c1=O +CCC1CN(c2cc(Br)ccn2)CCO1 +COC(=O)c1ccc(OC(C)C)c(NC(=O)C2CC2C)c1 +Cc1nnc(NCc2cccc(Cn3ccnc3)c2)c(C#N)c1C +Cc1noc(CCCC(=O)N2CCC(c3ccccc3)CC2)n1 +CCc1ccccc1OCC(=O)Nc1cccc(O)c1 +Cc1nc(C)c(C(=O)N(c2cccc3cccnc23)C2CCCC2)o1 +CCN(CC)C(=O)Cn1nc(C)c2cnn(-c3ccccc3)c2c1=O +Cc1cnn(C2CCCN(C(=O)c3nc(C(C)C)ncc3Cl)C2)c1 +CCc1ccccc1OCCN(C)C(=O)C1CCCN(C(N)=O)C1 +Cc1cc(S(=O)(=O)N2CCCCCC2c2ncon2)c(C)o1 +COCc1ncc(C(=O)NCc2ccc(C)cc2)c(N)n1 +CCOC(=O)CNc1ncc(Br)c2cccc(F)c12 +O=S(=O)(c1ccc(O)cc1)N1CC2CCC1C2 +c1ccc2[nH]c(CN3CCOC4(CCCC4)C3)nc2c1 +N#Cc1cccc(C(=O)Nc2ccc(F)c(NC(=O)C3CC3)c2)c1 +CN1CC(C(=O)N(Cc2cccc(F)c2)C2CC2)CC1=O +CC1(C)C(=O)C2(C(=O)N3CCN(c4ncccn4)CC3)CCC1C2 +O=C(NCCC1CC1)c1ccc(OCC(F)F)nc1 +COc1ccc(OC)c(NC(=O)c2cccc(-n3cccc3)c2)c1 +O=c1cc(C2CCC2)ncn1Cc1ccc(F)cc1 +O=C(NC1CCCCCC1)c1cccn1Cc1noc(C2CC2)n1 +CN(CCC#N)C(=O)C(Cc1ccccc1)NC(=O)c1ccco1 +O=C1Cc2cc(NC3CCN(c4c(F)cccc4F)C3=O)ccc2N1 +COc1cccc(CN(C)C(=O)c2ccc(C)o2)c1OC +COc1cc(C)cc(C(=O)N(CCC#N)Cc2ccco2)c1O +Cn1cnc(S(=O)(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +O=C(NCc1ccccc1F)c1cnc(N2CCOCC2)nc1 +CC(C)n1nccc1NC(=O)N(C)Cc1ccc(F)c(F)c1 +O=C(NCc1cccnc1)C1CSc2nccc(=O)n2C1 +CC(C)C(C)N(C(=O)NC1CC(=O)N(C(C)(C)C)C1)C1CC1 +CCN(CC)C(=O)N1CCC(C(=O)Oc2ccc3cn[nH]c3c2)CC1 +Cc1cc(C(N)=O)ccc1NC(=O)NC1CCOCC1 +Cc1csc(C(C#N)C(=O)CCCc2nc3ccccc3s2)n1 +Cc1ccc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c(O)c1C +CCc1onc(C)c1NC(=O)N1CCNC(=O)C1c1ccccc1 +Cc1oc(S(N)(=O)=O)cc1C(=O)NCCCCC(C)(C)C +Cc1cccn2cc(CC(=O)NC3(C#N)CCCCC3)nc12 +CCCC(=O)c1ccc(S(=O)(=O)Cc2ccccc2)cc1 +CC1CN(CCCNc2ncnc3c2oc2ccccc23)CC(C)O1 +Cc1ccncc1NCc1ccc(C(F)(F)F)cc1 +O=C(CSc1ccccc1Cl)N1CCN(C(=O)C2CC2)CC1 +Cc1ccn(C(C)CC(=O)NCCc2sccc2C)n1 +CCCCn1c(SC(C)C(=O)Nc2ncccn2)nc(C)c1C +CNC(=O)COC(=O)C1(Sc2ccccc2)CCCC1 +CCn1c(-c2nccnc2N)nc2cc(F)ccc21 +Fc1ccc2c(c1F)C(c1cc(Cl)ccn1)NCC2 +COCCNC(=O)CNc1nc2c(Cl)c(C)nn2c2ccccc12 +COc1ccc(C#CCNC(=O)c2cccc(N(C)C)c2)cc1 +Cc1ccc2nnc(C(=O)N3CCN(c4ccccc4)CC3)nc2c1 +O=C1Cc2cc(NC(=O)c3c[nH]c4cccc(F)c34)ccc2N1 +Cn1c(N2CCN(C(=O)c3cccc(F)c3)CC2)cc(=O)n(C)c1=O +COc1cccc(CC(=O)NCCc2nc3ccc(F)cc3n2C)c1 +CCCc1nc2sc3c(c2c(=O)n1NC(C)=O)CC(C)(C)OC3 +CC(C#N)(NC(=O)COc1c(Cl)cccc1Cl)C1CC1 +Cc1ccc(-n2nnc(C(=O)NCC(C)C)c2C)cc1F +CCCN(CC(=O)N(C)C)C(=O)c1sc(S(N)(=O)=O)cc1C +O=C1NCCOC2CN(S(=O)(=O)c3ccccc3F)CCC12 +Brc1cccnc1NCc1ccccn1 +N#Cc1ccc(NC(=O)N2CCCC2c2ccncc2)cc1 +CC(=O)NC(C)C(=O)NCc1cccnc1OC1CCCC1 +CCC1CCC(NC(=O)Nc2ccc3c(c2)CCC(=O)N3)CC1 +COc1ccc(-c2nnc(SCC(=O)NC3CC3)n2N)cc1 +CCCC(=O)Nc1ccc(Nc2cc(-n3ccnc3)ncn2)cc1 +CC(C)Cn1nccc1NC(=O)Cc1cccc(F)c1F +O=C(NCc1nnc2n1CCC2)N1CCC2CCCCC2C1 +FC(F)(F)c1ccnc(N2CCN(Cc3cocn3)CC2)n1 +Cc1ccccc1NC(=O)C(C)N1CCN(c2ncccc2C#N)CC1 +CCn1nc(-c2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 +Cc1nc(CNC(=O)CN2CCOCC2)oc1-c1ccc(Cl)cc1 +NS(=O)(=O)CCCNC(=O)C(c1ccccc1)c1ccccc1 +O=C(Cc1csc(-n2cccc2)n1)Nc1ccccc1 +O=C(Cc1ccsc1)Nc1ccc2c(c1)OCCCO2 +CC(C)n1ncc2cc(CNc3cccc(-c4nc[nH]n4)c3)cnc21 +CC(NC(=O)c1cccs1)C(=O)OCc1ccccc1 +COC(=O)Cc1c(OC)cc2oc(=O)ccc2c1OC +CCc1cnc(CNC(=O)NC2CCCC(C(F)(F)F)C2)s1 +Nc1ccccc1CCc1nc2c(s1)CCCC2 +CC(C(=O)Nc1ccc(-c2cn3cccnc3n2)cc1)c1ccsc1 +Cc1ccc(-n2ccc3nc(N4CCCC4)ncc3c2=O)cc1 +Cc1nc(C(C)NC(=O)c2cc(Cl)c[nH]c2=O)n[nH]1 +Cc1cc(NC(=O)c2cc3c(=O)n4ccccc4nc3n2C)no1 +CCOC(=O)c1c(C)nc(N)nc1COc1cccc(C)c1 +O=C(Cn1cnccc1=O)NCc1ccc(F)cc1 +CC(C)(C)OC(=O)N1CCC(CNc2ncccc2N)CC1 +O=C(NCc1ccccc1CN1CCOCC1)c1ccsc1 +Cc1ccc2oc(SCCN3CCCC3=O)nc2c1 +Cc1nc(S(=O)(=O)NCc2ccco2)c(C#N)c(C)c1Cl +Cn1nnnc1SCC(=O)Nc1ccc(F)cc1Cl +COCC(c1ccccn1)N(C)C(=O)CCc1cn2ccccc2n1 +Cc1cccc(Cc2nc3ccccn3c2CO)c1 +CC(NC(=O)N1CCC(n2cc(CO)nn2)CC1)c1ccc(F)cc1 +CC(C)(C)NC(=O)COC(=O)c1c2c(nc3ccccc13)CCC2 +C#Cc1cccc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)c1 +CN(Cc1c(Cl)ccc2cccnc12)Cc1nccn1C(F)F +COc1ccccc1OCC(=O)Nc1noc(-c2ccc(F)cc2)n1 +CC1CCN(C(=O)C2CCCCN2C(=O)c2ccco2)C(C)C1 +O=C(NCCc1ccccc1)NCC(=O)N1CCc2ccccc21 +COC(=O)c1ccc(CSc2nc(C)cc(N)n2)cc1F +CCOC(=O)N1CCN(C(=O)Cn2ccccc2=O)CC1 +O=C(c1ccco1)N(Cc1ccc2[nH]ccc2c1)C1CC1 +COc1ccc(NC(=O)NCCCc2c(C)noc2C)c(C)c1 +OC(c1ccccc1)C1NCCc2c(F)ccc(F)c21 +CCc1c(C#N)cnn1-c1ccc(Br)cc1 +CC(=O)c1ccc(NC(=O)C(C)Sc2nccn2C(C)C)cc1 +COCCNC(=O)c1cc2c([nH]c1=O)CCCC2 +Cc1ccc(-c2cnc(N3CCN(CCO)CC3)nc2)cc1 +CC(C(=O)OCc1ccc(F)cc1)S(=O)(=O)c1ccc(F)cc1 +COc1ccc(C)cc1NC(=O)CNC(=O)c1ccccc1C +O=C(CCc1nc(-c2ccncc2)no1)NCCc1ccco1 +Cc1cc(C(C)(O)CNC(=O)Nc2cnn(C)c2)c(C)o1 +CC(C)(C)CC(C)(C)NC(=O)C1COc2ccccc2O1 +Cc1cccc(C(=O)Nc2ccc(N)cc2Br)c1 +Cc1nc2ccncc2cc1C(=O)N1CCN(C)C(=O)C1 +O=C(Cn1ccc2ccccc2c1=O)NCCc1ccc(F)cc1 +CNc1scnc1C(=O)OC(C)C(=O)Nc1cc(F)ccc1F +Cc1ccc(C#N)cc1NC(=O)COC1CCCCC1 +CCC(CC)C(=O)NCC(=O)c1ccc(F)cc1 +N#Cc1cccc(CNC(=O)C2CC3CCC2O3)c1 +Cc1nc(NC(=O)c2cc(Cl)c3c(c2)OCCCO3)sc1C +O=C(CN1c2cccc3cccc(c23)S1(=O)=O)NCCCO +CCOc1ccc(C(=O)N2CCOC(C)(C)C2)cc1 +C=CCOC1C(CO)OC(n2cnc3c(N)ncnc32)C1O +COc1ccc2cc(-c3nc4ncccc4[nH]3)c(=O)oc2c1 +COCCN(CC(C)C)C(=O)c1ccc(O)c(Cl)c1 +COCCCNC(=O)c1ccccc1Sc1ccccc1C#N +O=C(Cn1ccc2ccccc2c1=O)NCCC1=CCCCC1 +Cc1n[nH]c(SCCNc2ccc(Br)cc2)n1 +Cc1cc(=O)n2nc(N3CCNC(=O)C3)sc2n1 +CC(C)C(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O +Cc1ccc(C(=O)Nc2ccc3oc(C(C)C)nc3c2)o1 +CS(=O)c1cccc(NC(=O)N(CCC#N)Cc2ccccn2)c1 +CCN(CC(C)C#N)C(=O)C(C)Oc1ccc(SC)cc1 +CCCCC(CC)C(=O)NCc1nc(C)sc1C +NC(=O)NCC(=O)NCCc1ccccc1Cl +O=C(NCCC(O)c1ccco1)c1ccccc1Br +NC(=O)C(OC(=O)CCc1ccc(F)cc1)C1CC1 +Cc1ccc(S(=O)(=O)c2ccc(Cn3cnc(C#N)n3)cc2)cc1 +O=C(NCc1nc(-c2ccccc2)cs1)c1ccc2[nH]cnc2c1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)c1ccc(C)cc1O +Cc1cc(Nc2ccc3[nH]c(C)cc3c2)n2ncnc2n1 +CC(NC(=O)C1CCCO1)c1ccc2c(c1)OCCO2 +CC(C)C(NS(C)(=O)=O)c1nnc2ccccn12 +Cc1oc2cc3oc(=O)c(CC(=O)N4CCCC4)c(C)c3cc2c1C +NC(=O)C1CCN(C(=O)c2ccccc2COc2ccccc2)CC1 +N#CCC1c2ccccc2CCN1C(=O)Nc1ccc(Cl)cc1 +Cc1nn(C)c(C)c1NC(=O)CSc1ccc2ccccc2n1 +CCCOc1cccc(NC(=O)CSc2ccncc2)c1 +CC(Sc1nc2c(c(=O)[nH]1)CCC2)C(=O)Nc1ccccc1 +CCOC(=O)CSc1nnc(-c2c[nH]c3ccccc23)n1CC +N#CC(C(=O)c1cccc(OCc2cscn2)c1)c1ccccn1 +CC(=O)NC1CCCN(C(=O)c2ccc(-c3ccco3)[nH]c2=O)C1 +O=c1[nH]c2ccccc2n1Cc1nc(Cc2ccc(Cl)cc2)no1 +C=C(C)COc1cccc(NC(=O)NCCc2ccccn2)c1 +CCOCc1ccccc1CNC(=O)C(C)NC(N)=O +CC(=O)N1CCC(NC(=O)N2CCC(C)CC2)CC1 +Cc1nc(C2CC2)nc(SCC(=O)NCc2ccco2)c1C#N +CCn1cc(NC(=O)NCC(O)c2cccc(Cl)c2)cn1 +COC(=O)C(NS(=O)(=O)c1ccc(Cl)cc1F)C(C)C +Cc1cccc(C)c1OCc1nnc(CCc2ccccc2)o1 +Cn1nncc1CN1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +COc1ccc(CNCCc2nnc3ccccn23)cc1 +COC(=O)c1c(NC(=O)c2cc(C)n(C)n2)sc2c1CCCCC2 +CCCC(=O)Nc1ccc(CNC(=O)NCC2CCCO2)cc1 +CSc1nccc(NC2CCN(C(=O)OC(C)(C)C)CC2)n1 +CCCC1CN(C(=O)c2cc(F)ccc2OC)CCO1 +NC(=O)CSc1ccccc1NCc1cccc2ccccc12 +CCCn1cnc2cc(NCc3ccncc3)ccc21 +COCC(=O)NCc1nc2ccccc2n1CCC(C)C +COc1ccc(Cn2cccc(N)c2=O)cc1Br +Cn1nc(CNC(=O)c2ccoc2)c2ccccc2c1=O +COc1cc(C)ccc1OCCCN1CCCS1(=O)=O +COC(=O)c1ccc(COc2ccc(N)cc2F)cc1 +CC(=O)c1ccc(NC(=O)Cc2cn(C)c3ccccc23)cc1C +CCOC(=O)c1sc2ccsc2c1CNC(=O)C(C)OC +CC(c1ccccc1)N1CC(C(=O)Nc2ccnn2C(C)C)CC1=O +CC1(C)CC(=O)c2c(O)cc(OCC(=O)Nc3cccnc3)cc2O1 +CCCCc1nnc(NC(=O)c2cc3ccccc3c(=O)[nH]2)s1 +CCn1c(=O)c(C)nc2cc(C(=O)NCc3ccc(C)o3)ccc21 +O=C1CCc2cc(OC(=O)Cc3ccc(Cl)cc3)ccc2N1 +CCN(CC=Cc1ccccc1)C(=O)c1ccc(S(C)(=O)=O)cc1 +O=C(Nc1ccccc1)c1cc2cnsc2s1 +Cc1nn(C)c2sc(C(=O)Nc3ccc(-n4cncn4)nc3)cc12 +COC(=O)c1cccc(NCC(=O)N2CCCC3CCCCC32)c1 +COc1ccc(-c2nn(CCC#N)cc2C(=O)N(C)C)cc1 +CCOc1ccc2c(c1OCC)C(CO)NCC2 +CN(Cc1c(F)cccc1Cl)S(=O)(=O)N1CCCC1CO +CCS(=O)(=O)N1CCN(C(=O)Cc2c(F)cccc2F)CC1 +CN(C1CCOCC1)S(=O)(=O)c1ccc(N)cc1Cl +COc1ccc(C(C)n2nc(C)cc2N)cc1OC +NC(=O)C(c1ccccc1)N1CCCC1Cn1cccn1 +CC(Sc1ccccn1)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CCCn1nc(C(=O)Nc2ccc(N(C)C)nc2)ccc1=O +O=C(c1ccc2c(c1)OCO2)N1CCN(S(=O)(=O)C2CC2)CC1 +Cc1cc(C)cc(OCCN(C)C(=O)c2ccc(=O)[nH]c2)c1 +O=C1NCCN(CC(O)COCc2ccccc2)C1c1ccccc1 +Cc1ccn(-c2ccc(NCC3CCN(CC(F)(F)F)C3)nn2)n1 +CCOc1ccc(NC(=O)N2CCN(CC)c3ncccc32)cc1 +Cc1ccc(NC(=O)CSc2nnc(C(C)C)o2)cc1 +c1cnc(-n2cccn2)c(CNc2nc3ccccc3s2)c1 +CC(NC(=O)CCc1nc2ccccc2[nH]c1=O)c1ccccc1 +CN(C)C(=O)c1ccc(N2CCCC(OCCO)C2)nc1 +Cc1ccn(CC(=O)N2CCCC(Nc3ccc(F)c(F)c3)C2)n1 +COc1c(F)ccc2c1CCNC2Cc1ccc(O)cc1 +CC(CC#N)Sc1ccccc1NC(=O)CSc1ccccn1 +CC(COCC(F)(F)F)NC(=O)N(C)Cc1ccc(C#N)cc1 +Cc1ccccc1C(C)NC(=O)CCn1cnc2c(cnn2C)c1=O +O=C(c1cscn1)N(Cc1ccccc1)CC(O)c1cccs1 +Cc1ccccc1CNC(=O)c1cnc(-c2ccccc2)nc1C +C#CCn1c(-c2ccc(C)c(C)c2)ccc(C#N)c1=O +COC(=O)CCc1csc(COc2ccc(C)cc2C)n1 +COCc1cc(CN(C)C2COc3ccccc3C2)n[nH]1 +CNC(=O)c1ccccc1NC(=O)c1ccc(C(C)C)cc1 +Cc1nc(C(=O)N2CCN(CC3CC3)c3ccccc32)ccc1C#N +Cc1ccc(C)c(NC(=O)Cc2nc3ccc(N)cc3o2)c1 +CCCCNC(=O)Nc1ccc(C(=O)NC2CCOCC2)cc1 +COc1ccc(F)cc1CS(=O)(=O)c1ccc(N)cc1 +CC1CN(c2ccccc2NC(=O)NC(C)C2CCCO2)CC(C)O1 +COc1cccc(C(C#N)NCc2ccc3c(c2)OCO3)c1 +COc1ccc(Cl)cc1NC(=O)c1ccncc1 +CCc1nc(CN(C)C(=O)OC(C)(C)C)sc1C +CNS(=O)(=O)c1ccc(C(=O)NC2CCc3c(O)cccc32)cc1 +CC(=O)N1Cc2ccc(C(O)c3cccs3)cc2C1 +C#CCOc1ccc(NC(=O)Cc2cccc(F)c2F)cc1 +O=C1NCCC1N1CC(c2ccccc2)(c2ccccc2)CCC1=O +Cc1cccc(-c2nnc(CN(CCC#N)Cc3ccco3)o2)c1 +COc1ccnc(C(=O)Nc2ccc(F)cc2OCC2CC2)c1 +O=c1[nH]c(Nc2ncccn2)nc2c1cnn2-c1ccccc1 +CC1CCC2C(CCCN2C(=O)c2cccc(N3CCNC3=O)c2)C1 +CN(Cc1cccs1)C(=O)NCc1nc2ccccc2s1 +Cc1cc(C)n(Cc2ccc(C(=O)NCCS(N)(=O)=O)cc2)n1 +O=C(NCCCOCc1ccco1)C1COc2ccccc2O1 +COc1cc(S(=O)(=O)N2CC(C)OC(C)C2)c(OC)cc1C +O=C(Cc1ccccc1)N1CCN(Cc2nnc(C3CC3)o2)CC1 +CCc1ccc(OCC(=O)Nc2ccc(O)cc2)cc1 +O=C(NCc1cscn1)c1n[nH]c2ccccc12 +CCNS(=O)(=O)c1cc(C)c(C)c(N)c1OC +Brc1ccc(-c2ccnc3ccnn23)cc1 +CC(c1ccccc1)N(C)C(=O)Nc1ccc2c(c1)COC2 +CN(Cc1nc2ccccc2s1)C(=O)Nc1cccc2[nH]ccc12 +CC1=C(Cc2cn(C(C(N)=O)C(C)C)nn2)C(C)(C)CCC1 +C=CCc1nnc2c(CS(=O)(=O)c3cccc(Cl)c3)cccn12 +O=C(c1ccc(F)cc1F)N1CCN(CCOc2ccccc2)CC1 +Cc1ccc2oc(C(=O)OCC3CC(=O)N(C4CC4)C3)cc2c1 +CCCC(=O)Nc1cccc(CNC(=O)NCC(F)(F)F)c1 +CCOc1cc(CNc2ncnc3[nH]cnc23)ccc1OC(F)F +O=S(=O)(NCCNc1ccccn1)c1ccc2c(c1)OCCO2 +CCN(C(=O)Cc1c(C)nn(C)c1C)c1cccnc1 +Cc1oc(-c2ccsc2)nc1CC(=O)NC1CCCc2occc21 +Cc1ccc(C)n1-c1c(C(=O)OCC2CC=CCC2)cnn1C +Cc1noc(C)c1CNC(=O)C1(c2ccccc2)CCCC1 +CC(C)NC(=O)Cc1cc(-c2ccc3c(c2)CC(C)O3)on1 +O=C1CC2(CCN(C(=O)Nc3ccccc3)C2)Oc2ccccc21 +COC(=O)COc1ncnc2sc3c(c12)CCC3 +CC(C)NC(=O)c1cccc(CNC(=O)NCC(C)(C)C)c1 +CCOc1cc(C(=O)NCC2CCOC2)ccc1OC +Cc1ccccc1OCC(=O)N1CCC(c2nnc(C(C)C)o2)CC1 +COc1cc(OC)c(NC(=O)NCC2(O)CCCCCC2)cc1F +CCC(=O)Oc1ccc2nc(-c3cccc(OC)c3)oc(=O)c2c1 +O=C(COC(=O)COc1ccc(Cl)cc1Cl)NC1CC1 +O=C(Nc1cccc(Cn2cccn2)c1)c1ccccc1F +Cc1noc(C)c1NC(=O)COc1cc(Cl)ccc1Cl +CCOC(=O)c1ccc(NC(=O)CNC(=O)c2ccc(C)cc2)cc1 +CC1c2cccn2CCN1C(=O)Cn1ccc(=O)[nH]c1=O +COc1ccc(S(=O)(=O)NCc2ccc(-n3cccn3)cc2)cc1 +CCc1cc2c(=O)n(Cc3ccc(C(=O)OC)c(F)c3)cnc2s1 +Cc1noc(C)c1C(=O)NCc1ccc(S(N)(=O)=O)s1 +CCCn1nnc(NCc2ccccc2Cl)n1 +CCOc1cccc(C(=O)NC(C)c2nc3ccccc3[nH]2)c1 +CCN(CC(C)C#N)C(=O)CN1CCOC(C(N)=O)C1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)C1CCC1 +CCOc1ccccc1NC(=O)C(C)n1nc(C)ccc1=O +CCOc1ccc(-c2nc(C(=O)NC(C)C)cs2)cc1 +CCCc1ncncc1C(=O)N1CCC(N2CCCC2=O)CC1 +CNC(=O)c1nn(-c2ccc(Cl)cc2)ccc1=O +Cc1cccc(NC(=O)CSc2ncnn2C)c1C +COC(=O)c1c(SCCCC#N)nc(=O)[nH]c1C +CC1COCC(C)N1CC(=O)N1CCNC(=O)C1 +Cc1occc1-c1nnc(SCC(=O)N2CCOCC2)n1N +Cc1nc2c(s1)CN(C(C#N)c1cccs1)CC2 +COCc1cc(C)n(CC(=O)Nc2ccc(Cl)cc2)c(=O)c1C#N +CCC(NC(=O)C1CC(=O)N(C(C)C)C1)c1c(C)nn(C)c1C +CCOc1ccccc1CNC(=O)c1cnc(CC)nc1C +Cc1noc(CSc2nc3ccc(Cl)cc3o2)n1 +Cc1nc(CN)nc(-c2cc3c(cc2C)OCCO3)n1 +C#CCOc1ccc(NC(=O)NCCCc2c(C)noc2C)cc1 +Cc1csc(-c2ccc(NC(=O)c3c(C)nn(C)c3C)cc2)n1 +O=C(Nc1ccnc(-c2ccncc2)n1)c1ccc(Cl)cc1 +COc1ccccc1NC(=O)c1ccc(C(C)C)nc1N +CCCCS(=O)(=O)Nc1c(C)n(C)n(-c2ccccc2)c1=O +Cc1cc(NC(=O)c2ccc(=O)n(C)n2)ccc1C(=O)N(C)C +N#Cc1cccc(NC(=O)c2ccc3ncsc3c2)c1 +CC(C)CNC(=O)c1ccc(NC(=O)c2ccc(=O)n(C)c2)cc1 +O=C(NC1CCCN(c2cccnc2)C1=O)c1ccco1 +CCCCCNC(=O)COc1ccc2c(C)cc(=O)oc2c1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)OCc1ccccn1 +CN(C)C(=O)N1CCC2(CC1)COCCN(c1ncccn1)C2 +COC(=O)CC1CN(Cc2cccnc2C)CCO1 +CC(C)NC(=O)CCCNC(=O)c1cnc2cccnn2c1=O +CC(C)(CNC(=O)C1CCCOC1c1ccccc1)c1ccncc1 +CCn1cnnc1CNC(=O)C(C)Oc1cccc(C)c1 +C=CCN1CCN(C(=O)c2c(Cl)cccc2Cl)CC1 +COCc1ncn(Cc2nc(-c3ccc(OC)cc3F)oc2C)n1 +Cc1ccccc1S(=O)(=O)N1CCN(CC(C)O)CC1 +CCS(=O)(=O)N(C)c1ccc(C(=O)N(C)C)cc1 +CC(C)(CO)n1ccc2c(nnc3ccnn32)c1=O +CC(NC(=O)c1nc(-c2ccncc2)no1)c1ccccc1 +Cc1ccccc1C(=O)Nc1ncn(Cc2cccc(F)c2)n1 +CC(=O)Nc1ccc(N2CC(C(=O)Nn3cnnc3)CC2=O)cc1 +CCOC(=O)C(C)CNC(=O)Cc1c(F)cccc1F +CN(CCc1ccc(F)cc1)C(=O)C(N)c1ccccc1 +O=C1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CCN1 +Cc1cnc(CNC(=O)c2ncn3c2C(=O)NCC3)cn1 +Cn1nc(C(C)(C)C)cc1NC(=O)CN1C(=O)COc2ccccc21 +CCc1nc(C2CCCN(C(=O)c3cn4c(C)cccc4n3)C2)no1 +O=c1[nH]c(SCC2CCCO2)nc2c1cnn2-c1ccccc1 +CC(=O)c1cccc(NC(=O)c2noc3c2CCc2ccccc2-3)c1 +Cc1cc(C(=O)NCCn2cnnc2C)c(C)cc1Br +CCNC(=O)CN(CC)C(=O)c1cn(-c2ccccc2Cl)nn1 +Cc1ccc2c(c1)NC(=O)C2CC(=O)N(C)Cc1ccsc1 +CCC1CCCCN1c1ncnc(N2CCCCC2)c1N +CSc1cccc(NC(=O)c2nnn(-c3ccccc3)c2C)c1 +CC(C)CCCC(C)NC(=O)Nc1ccc(S(C)(=O)=O)cc1 +CCOC(=O)C(O)(c1cn(C)c2cccc(Cl)c12)C(F)(F)F +CNc1nnc(-c2nnc3sc(C)c(C)n23)s1 +Cc1sc(=O)n(CC(=O)N(C2CCC(C)CC2)C2CC2)c1C +COc1ccc(C(NC(=O)c2ccnnc2)c2ccc(F)cc2)cc1 +OCCN1CCN(Cc2csc(-c3ncccn3)n2)CC1 +COc1ccc(C2CCCN2C(=O)c2ccccn2)cc1 +COc1ccccc1CNC(=O)c1c(C)nc(C(C)C)nc1SC +O=C(NCCNC(=O)c1ccccc1)Nc1ccccc1F +CC1CC1CN(C(=O)c1nccn2ccnc12)C(C)C +Cc1cc(NC(=O)COc2ccc(Cl)cc2Cl)nn1C +N#Cc1ccc(Cn2nnc(-c3ccccc3)n2)cc1 +Cc1noc(C2CN(S(=O)(=O)Cc3cccc(F)c3)C2)n1 +CCOC(=O)c1cc2nc(-c3ccccc3)cc(C)n2n1 +CC(C)(CO)CNc1cnn(Cc2ccccc2)c1 +CCc1cc(C)c(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)o1 +O=C(c1ccccn1)N1CCN(CC2CCCO2)CC1 +CN(C)C(=O)C(C)(C)NC(=O)c1cccc(Nc2cnn(C)c2)c1 +CCOC(=O)c1c(C)[nH]c(C(=O)N2CCOCC2C2CC2)c1C +CCCCOC(=O)Cn1nc(C#N)cc1-c1ccco1 +O=C(OCCc1cccnc1)c1cccc(Oc2cnccn2)c1 +CC1CN(c2ccccc2CN2CCOC(C(N)=O)C2)CC(C)O1 +CCn1cc(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)cn1 +N#CC1C(=O)N=C(c2cccs2)C=C1c1cccs1 +NC(=O)CC1CCN(C(=O)NCCC(=O)NC2CCCC2)CC1 +CC(C)(C)OC(=O)N1CCCC(NC(=O)C2CC(=O)C2)C1 +CC(NC(=O)CCn1cnc2sccc2c1=O)c1ccc(F)cc1 +CC1(C)Cc2c(c(-c3ccccc3)[nH]c(=O)c2C#N)CO1 +O=C(Nc1cc(F)ccc1Cl)c1ccc(N2CCOC2=O)cc1 +CCCc1nc2ccc(OCCCO)cc2s1 +Cc1cnn(Cc2cc(F)ccc2F)c1NC(=O)NC1CC1 +COC(=O)C(O)c1cc(OC)c(OC)c(OC)c1 +COCCN1CCN(C(=O)Cc2cn(C)c3ccccc23)CC1=O +Cc1ccc(C(=O)Nc2ccccc2)cc1NC(=O)NCc1ncc[nH]1 +CCC1CN(C(=O)NCc2cccnc2-n2cccn2)CCO1 +CN(Cc1ccccc1)C(=O)c1ccc(N(C)S(C)(=O)=O)cc1 +O=C(C1Cc2ccccc2S1)N1CCC(CO)CC1 +Fc1cc(Cl)cc2c1C(c1cccnc1)NCC2 +Cc1cc2nc(C)c(CCC(=O)NCc3ccccc3C)c(C)n2n1 +Cc1cccc(N(C)C(=O)Cn2cnc3ccccc3c2=O)c1C +CC(=O)c1cccc(S(=O)(=O)Oc2ccc3ccc(=O)oc3c2)c1 +Cc1ccc(C(=O)Nc2c(C)cccc2C)cc1N +Cc1cc(C(=O)N2CCC3(CC2)OCC(=O)NC3C)no1 +Cc1onc(-c2ccccc2F)c1C(=O)N1CCCC1 +CCOC(=O)CC(C)c1c(C)n(C)c(=O)n(C)c1=O +CCS(=O)(=O)NCC#Cc1ccc(N(C)C)cc1 +Cc1ccc(Cc2nnc(NC(=O)Nc3cccs3)o2)c(C)c1 +O=C1CCCN1CCOc1ccc(Br)c2cccnc12 +CCc1ccc(NC(=O)C2COc3ccccc3O2)cc1 +CS(=O)(=O)N(CC(=O)NC1CCCCC1)c1ccc(C#N)cc1 +COCCCNC(=O)CNc1cccc(C)c1C +Cn1nnc2cc(C(=O)N3CCC(c4ccccc4)C3)ccc21 +CCc1ccc(-c2nnn(Cc3nc4c(C)cccc4c(=O)[nH]3)n2)cc1 +CC(=O)Nc1ccc(SC(C)C(=O)N2CCNCC2)cc1 +Cc1cccc(CNC(=O)Nc2ccc3c(c2)OCCCO3)c1 +Cc1ccccc1NC(=O)NCCCn1ccc2cccnc21 +CCc1ccccc1OCC(=O)NCc1nc2ccccc2[nH]1 +Cc1ccc(C(CC(=O)NCc2ccco2)c2ccco2)cc1 +CCc1nc(CCNc2ncnc3nc(C)cc(C)c23)no1 +CSc1ccccc1NC(=O)c1cc(S(N)(=O)=O)c(C)o1 +CN(C)C(=O)COC(=O)c1ccccc1NC(=O)c1ccco1 +CCn1cc(C(=O)N(CC(N)=O)C2CCCC2)c2ccccc21 +CCc1ccc2oc(=O)cc(CNC(=O)c3cccc(OC)c3)c2c1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccco1 +Cc1ccsc1C(=O)N1CCc2ncnc(NC(C)C)c2CC1 +Cc1cc(NC(=O)C2CC(=O)N(c3cc(Cl)ccc3C)C2)no1 +CC(C)C(=O)Nc1ccc(C(=O)C(C)OC(=O)c2cccs2)cc1 +CCN(CC)C(=O)c1ccccc1NC(=O)Cc1ccc(C)c(C)c1 +COC(=O)c1cccn2cc(Cn3cnc(C4CCC4)cc3=O)nc12 +CCCCn1nc(C(=O)NCCOC)ccc1=O +O=C(c1ccc2c(c1)OCO2)N1Cc2cncnc2C1 +CCN(CC)C(=O)c1ccccc1NC(=O)Cc1ccc(OC)cc1 +Fc1ccc2ncn3nc(-c4ccncc4)nc3c2c1 +CCCNC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +COc1ccc(OCc2nc(-c3ccccn3)no2)cc1 +CC(C)(C)n1cc(NC(=O)Nc2ccc3oc(C4CC4)nc3c2)cn1 +CCn1c(C)cc(C(=O)Nc2cnc3c(cnn3C(C)C)c2)c1C +CCc1cccc(C)c1NC(=O)Cc1csc(N2CCNC2=O)n1 +Cc1c(C)c2c(c(C)c1N)OC(c1ccccc1)C(=O)N2C +CC(=O)Nc1ccc(NC(=O)c2cnn(-c3ccccc3)c2C)cc1 +Cc1cc(OC(F)F)c(C(=O)NC(C)CN2CCCC2=O)s1 +CCN(C(=O)C(C)S(=O)(=O)c1cccc(OC)c1)c1ccccc1 +Cn1cc(C2(C)CN(C(=O)Cc3cc(F)ccc3F)CCO2)cn1 +COCc1cc(=O)[nH]c(C2CCCN(Cc3ccc(OC)cc3)C2)n1 +COc1ccccc1CNS(=O)(=O)c1c[nH]cn1 +COCn1c(=O)c2c3c(cnc2n(C)c1=O)C(=O)CC(C)(C)C3 +O=C(NCc1nc(-c2cccs2)no1)NC1CCCCC1 +NS(=O)(=O)Cc1ccc(CNC(=O)c2ccncc2)cc1 +CCCc1ccc(C(=O)N2CCC3(CCCO3)CC2)cc1 +CC1CCN(C(=O)CCCC(O)c2ccc(Cl)cc2)CC1 +Cn1cccc1C(=O)N1CCC2(CC1)CCN(CC1CCCC1)C2=O +COc1ccc(NC(=O)Cc2ccccc2N)cc1 +COc1cccc(OC2CN(C(=O)c3ccc(-c4cc[nH]n4)cc3)C2)c1 +COc1ccccc1CNC(=O)Cn1ncn2cccc2c1=O +CS(=O)(=O)NCc1noc2c1CN(C(=O)C1CCC1)CC2 +O=C(NCC1CCCOC1)c1cc2ccccc2[nH]1 +CCc1cccc(NS(=O)(=O)c2cn[nH]c2)c1 +CC(C)Cn1cc(C(=O)NC2CC2)c(=O)c2c(N)cccc21 +CC(=O)c1ccc(S(=O)(=O)NCCc2ccc(F)cc2F)cc1 +COc1cc(CNc2cnns2)cc(OC)c1O +Cc1cc(C(=O)Nc2ccc(F)cc2C)c2c(=O)[nH]n(C)c2n1 +CN(Cc1ccccc1)c1nc2nc[nH]c(=O)c2s1 +CNC(=O)c1cc(NC(=O)Cc2ccc(F)cc2F)ccc1Cl +O=C(N=c1[nH]nc2ccccn12)c1cc(-c2ccccc2)no1 +C=CCOc1ccccc1CNc1ccc(NC(C)=O)cc1 +COc1cccc(CC(=O)N2CCCC2c2nc(C)c(F)c(=O)[nH]2)c1 +CC1CCC(NC(=O)Cn2nc(-c3ccco3)cc(N)c2=O)CC1 +CCc1sc(C(=O)Nc2cnccn2)cc1Br +CSc1nnc(CSc2nc(Cc3cccs3)n[nH]2)s1 +CCNS(=O)(=O)c1ccc2c(c1)OCCCO2 +O=C(c1cc(F)ccc1O)N1CCc2cc(F)ccc2C1 +Fc1ccc2c(c1Cl)CCNC2Cn1cnnn1 +COc1ccc(C)cc1Cn1nc(C)c(C)c(C#N)c1=O +Cc1cccc(CN(C(=O)c2cc(F)cc3[nH]cnc23)C2CC2)c1 +CC(COc1ccc(F)cc1F)NC(=O)C1CC(=O)N(C)C1 +CCOC(=O)C1CCCN(C(=O)c2cc(F)ccc2N)C1 +CCOC(=O)Nc1ccc2c(c1)C(O)c1ccccc1-2 +CCC1CN(CC(=O)N2CCCCCC2)c2cc(C(C)=O)ccc2O1 +CCCn1ccc(C(=O)Nc2ccn(CC#N)n2)n1 +COCC(=O)NCc1nc2ccccc2n1Cc1ccccc1 +C=CCN(CCc1ccccc1)C(=O)NCc1ccc(C)nc1 +Cc1nonc1C1CCCN1C(=O)Cn1ccnc1-c1ccccc1 +c1cncc(CN(Cc2noc(-c3ccoc3)n2)CC2CCCO2)c1 +Cc1n[nH]cc1CNc1ccc(Br)cn1 +Cc1c(C(=O)NCCO)oc2c1ccc1ccccc12 +COc1ccc(N(CCO)S(C)(=O)=O)cc1OC +C#CCOCCC(=O)Nc1cc(Cl)c(O)c(Cl)c1 +CNC(=O)c1cccc(N2CCCC(c3nc4ccccc4o3)C2)n1 +NC(=O)c1ccc(NC(=O)C2COc3ccccc3C2)cc1 +Cc1ccc(CC(=O)N2CCN(C(=O)c3ccncc3)CC2)s1 +COCCN(Cc1ccoc1)C(=O)Nc1ccc2c(c1)OCO2 +CN(CCCc1ccccc1)C(=O)c1cccc(N2CCCC2=O)c1 +COCCN(CC(=O)N(C)C)C(=O)c1c[nH]c2cccc(F)c12 +CCn1c(=O)oc2cc(NC(=O)Nc3ccc(C)c(F)c3)ccc21 +Cc1nc(N2CCCC2)nc2c1CCN(C(=O)c1c[nH]cn1)CC2 +CCN(CC)C(=O)c1nn(-c2ccccc2F)c(=O)n(CC)c1=O +CC(C)(C)OC(=O)N1CCc2nc(-c3ccccc3)ncc2C1 +Cc1snc(S(=O)(=O)Cc2ccccc2Cl)c1C#N +CC(Sc1nc(-c2ccccn2)n[nH]1)C(=O)Nc1cccc(F)c1 +Cc1cc(F)ccc1NC(=O)c1cccnc1N1CCOCC1 +COc1ccc(CC(C)N(C)C(=O)CCn2cc(C)cn2)cc1 +COc1ccccc1Nc1ncccc1C(=O)NC(C)c1ccncc1 +Cc1ccc(CCCCC(=O)N(C)CC(N)=O)cc1 +O=C(c1cccnc1)N1CCC(c2nc(-c3ccccc3)no2)C1 +COC(=O)c1ccc(NC(=O)c2ccccc2OC(C)=O)cc1 +O=C(CSc1cc(F)ccc1F)NCC1CCCO1 +CCOC(=O)C1=C(COC)Nc2ncnn2C1c1sccc1C +O=C(Nc1cnc(N2CCCC2)nc1)c1ccc(F)cc1 +O=C(Nc1ncn(Cc2cccc(Cl)c2)n1)c1cccnc1 +COc1cc(F)cc(NC(=O)c2cnn(-c3ccncc3)c2C)c1 +Cc1nc(NCCNC(=O)c2cccs2)cc(N2CCOCC2)n1 +O=C(NCC(=O)N1CCC2CCCCC21)c1ccccc1 +Cn1c(SCC(=O)Nc2sccc2C#N)nnc1C(F)(F)F +O=C(CCNC(=O)c1ccccc1)NCc1ccncc1 +O=C(Oc1cccc(F)c1)c1cncc(Br)c1 +CC(C)Nc1nnc(SCC(=O)NCC(=O)N(C)C)s1 +O=C1Nc2ccccc2C1NCCc1ccccn1 +CC(C(=O)c1c[nH]c2ccccc12)N1CCn2c(nn(C)c2=O)C1 +CCC(C)NC(=O)CNc1ccc(F)c(C(N)=O)c1 +Cc1nn2c(CO)c(-c3ccc4c(c3)ncn4C)nc2s1 +CC(NC(=O)c1ccc(Cl)c(N)c1)c1ccccc1 +OC(CNCc1ccccc1)c1ccc2c(c1)CCCC2 +CCc1ccc(-n2nnnc2C=CN2CCOCC2)cc1 +CCN1C(=O)CCc2cc(NC(=O)c3ccc(OC)cc3)ccc21 +CCCCN(CCCC)C(=O)c1cncc(Br)c1 +C=CCOc1cccc(NC(=O)c2c[nH]c3ccccc3c2=O)c1 +CCC(C)(O)c1cn(-c2ccc(Cl)cc2)nn1 +Cc1nc(C)c(C(=O)Nc2cnc3c(c2)c(=O)n(C)c(=O)n3C)s1 +CCCSc1nnc(NC(=O)c2ccc3nnsc3c2)s1 +Cc1cc(C(F)F)n2nc(C(=O)Nc3ccc4c(c3)OCO4)nc2n1 +O=C(CNC(=O)c1ccn(-c2cccc(F)c2)n1)Nc1cn[nH]c1 +Clc1ccc(NCc2nnc3n2CCCC3)cc1 +Cc1cc(Nc2ccc(S(=O)(=O)N(C)C)cc2)ncn1 +Cc1n[nH]cc1NC(=O)Cc1ccc(OC(F)F)cc1 +Cn1nnnc1SCCC(=O)NCC1(c2ccc(F)cc2)CCC1 +O=C(CNS(=O)(=O)c1cn[nH]c1)NCc1ccco1 +Nc1nc(C(F)(F)F)c(Cc2cccnc2)c(=O)[nH]1 +CC1=NC(CNc2cc(C(=O)N3CCCCC3)ccc2Cl)N=C1 +O=C(NCc1ccccc1)c1csc(COc2ccc(F)cc2)n1 +CS(=O)(=O)N1CCc2sccc2C1c1ccccc1 +O=C(NCCc1ccccc1)c1ccc(Cl)c(-n2cnnn2)c1 +Cc1ccc(-c2nc3sc4c(n3c2C)CCNC4)cc1 +O=C(Cc1ccccc1O)NCc1ccnc(OC2CCC2)c1 +CC(=O)c1cnc(-c2cn(C)c3ccccc23)s1 +O=C(NCC1CC1)C1CCN(c2ccccc2Cl)C1=O +CCOC(=O)CCC(=O)Nc1ccc(OC)cc1 +CC(C)OCc1cccc(CNC(=O)c2c(F)cccc2F)c1 +Cc1nnc(-c2ccccc2-c2ccc(N)nc2)s1 +NC(=O)C1CCN(C(=O)CCC2CCCOC2)c2ccccc21 +CSc1ccc(NC(=O)C2CCC(=O)N2)cc1 +O=C(NCC1(c2ccccc2)CC1)c1csnn1 +COC(=O)CNC(=O)Cn1cnc2sc(C)c(C)c2c1=O +O=C1c2ccccc2C2N1CCC1CCc3ccccc3N12 +O=c1c(OCc2ccc(F)cc2)cccn1CCCO +O=C(NC1CC1)C1CCCN(c2snc3ccccc23)C1 +Cc1cc(C)cc(NC(=O)CCc2c(C)nn3cnnc3c2C)c1 +O=C(NCC1CCN(C(=O)c2ccccc2F)CC1)C1CCCCC1 +O=C(c1ccoc1)N1CCCn2nnc(COCC3CC3)c2C1 +CSc1ccc(NC(=O)NCc2cnn(C)c2C)cc1Cl +CC(C)(Oc1ccc(F)cc1)C(=O)OCC(=O)N1CCCC1 +Cc1nnc(SCC(=O)N2CCCc3ccccc32)s1 +CCn1ncc(-c2cc(C(F)(F)F)n3ncc(Cl)c3n2)c1C +O=C(CN1c2cccc3cccc(c23)S1(=O)=O)NCC(F)(F)F +Cc1cccc(OCC(O)CN2CCOC(Cn3cc(C)cn3)C2)c1 +O=C1OC(C(=O)OCCCc2ccncc2)Cc2ccccc21 +Cn1cc(CCCSc2ccc3c(c2)OCCCO3)cn1 +Cc1ccc(NC(=O)Cn2nnc(-c3cccs3)n2)cc1 +NC(=O)c1cccc(C(=O)Nc2cccc(Oc3cnccn3)c2)c1 +COc1ccc(CNC(C)C(N)=O)cc1Br +O=C(Cc1cccs1)N1CCC2C1CCN2c1nncs1 +N#CC(C(=O)CCCSc1ccc(Cl)cc1)c1ccccn1 +CN(C)C(=O)c1ccc(OC(=O)CCCc2cc(F)ccc2F)cc1 +CCOc1ccccc1OCC(=O)Nc1cccc(S(C)=O)c1 +CC(=O)N1CCC(C2NCCc3cc(F)ccc32)CC1 +O=C(Cn1nnn(-c2ccccc2)c1=O)NCc1cccc(Cl)c1 +C=CCn1c(=O)c(C(=O)Nc2ccncc2)c(O)c2ccccc21 +CCc1cc(-c2cnn(C)c(=O)c2C(C)=O)ccc1OC +Cc1ccc(S(=O)(=O)NC2CCOCC2)c2c1NCCC2 +Cn1ncc2c(=O)n(CC(=O)OCC(N)=O)cnc21 +OC(CNc1ccc(Oc2ccccc2)cc1)c1ccccn1 +COc1ccc(-c2cn3cc(Br)cnc3n2)cc1 +CCNC(=O)N1CCN(c2nc3c(F)cccc3s2)CC1 +Cc1ncsc1C(=O)NC1(CO)CCCC(C)C1 +CCNC(=O)c1csc(Nc2ccc(S(C)(=O)=O)cc2)n1 +COc1ccccc1CNc1n[nH]c2nc(C)cc(C(F)(F)F)c12 +CCOc1ccc(CC(=O)NCC(F)(F)F)cc1 +CCNC(=O)CN(CC)S(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +CC1CN(C)c2ccccc2N(C(=O)c2cccn2C)C1 +CCOc1ccc(CC(C#N)C(=O)N2CCCCCC2)cc1 +CC(C)(C)C(=O)Nc1ccccc1C(=O)NCCN1CCOCC1 +COC(=O)C(NC(=O)OC(C)(C)C)c1ccc(Cl)cc1 +CCN(CC)C(=O)CNc1ccc(Br)cc1Cl +CCOc1ncccc1CNC(=O)Nc1ccccc1C +CC(C(=O)N1CCc2ccccc2C1)N1CCc2cc(F)ccc2C1 +COc1ccccc1S(=O)(=O)CC(=O)Nc1cccc(Cl)c1 +CC(=O)Nc1cc(-c2ccccc2)nn1Cc1ccccc1 +COc1ccc(CNC(=O)N(C)Cc2ccco2)c(C(F)(F)F)c1 +Cc1ccc(-c2ccc(=O)n(CCC#N)n2)c(C)c1 +COC(=O)c1ccc(C(=O)Nc2cc(-c3ncco3)ccc2C)o1 +CCc1onc(C)c1NC(=O)CNC(=O)OC(C)(C)C +CCc1noc(C2CCCN(C(=O)c3cccs3)C2)n1 +Cc1ccc(S(=O)C(C)C(=O)Nc2ccc(C(C)(C)C)cc2)nc1 +Cc1nc(CC(=O)NCCSc2ccc(Cl)cc2)cs1 +COc1ccc(CNC(=O)CN2C(=O)CSc3ncccc32)cc1 +NC(=O)CNC(=O)c1cccc(OCc2ccc(F)cc2F)c1 +OCc1sc(CCOc2ccccc2)nc1C1CC1 +O=C(Nc1cn[nH]c1)C1CC(=O)N(CC(F)(F)F)C1 +Cc1ccc2nc(SCC(=O)NC3CC3)[nH]c2c1 +CCOc1cc(S(=O)(=O)NCCOC)ccc1Br +CCOC(=O)N1CCN(C(C)C(=O)Nc2ccnn2C(C)C)CC1 +COCc1nc2ccc(NC(=O)c3ccc(OC)cc3)cc2[nH]1 +COc1cc(C2(C#N)CCC(=O)CC2)cc(OC)c1OC +O=C(Cc1cc(Cl)c2c(c1)OCCO2)NCC1CCCO1 +O=C(CN(C(=O)C1CCOC1)c1ccccc1)N1CCCCC1 +CN(CC(=O)c1c(N)n(C)c(=O)n(C)c1=O)Cc1ccsc1 +Cc1sc2ncc(C(=O)Nc3ccc4c(c3)OCO4)c(=O)n2c1C +CN(C)S(=O)(=O)c1ccc(Br)cc1Br +CC(NC(=O)c1ccc(=O)n(-c2ccc(F)cc2)n1)C1CCCCC1 +COc1cccc(C(=O)CCC(=O)Nc2ccccc2)c1 +CN(C(=O)c1ccco1)C1CCc2ccccc2C1 +Cn1c(NCC2CCCC2)c(C#N)c(=O)n(C)c1=O +CNC(=O)C(C)Sc1nnnn1-c1cccc(F)c1 +CCOc1ccc(S(=O)(=O)N2CCOCC2)cn1 +O=C(Cc1c(F)cccc1F)NCCNC(=O)c1cccnc1 +Cc1nccn1-c1ccc(CNC(=O)CCc2ccc(F)cc2)cc1 +O=C(NCCc1nnc2ccccn12)c1ccc(NC(=O)C2CC2)cc1 +CCCc1noc(CS(=O)c2nnc(-c3ccc(C)cc3)n2C)n1 +c1cncc(Oc2ccccc2CSc2ncn[nH]2)c1 +COc1cccc2c1N(CC(=O)Nc1cc(C)no1)CCC2 +CCCC1CN(C(=O)c2ccc(N(CC)CC)nc2)CCO1 +CCc1ccc(S(=O)(=O)Nc2[nH]ncc2C(N)=O)cc1 +CCOC(=O)CN(C1CC1)S(=O)(=O)C1CCCCC1 +O=C(c1cccc(NC(=O)C2CCCO2)c1)C1CC1 +Cc1cc(C(=O)Nc2ncn(CC(=O)N3CCCCCC3)n2)on1 +CCN(CC)c1ccc(S(=O)(=O)NC)cc1N +C#CCNC(=O)CC1CCCc2cc(OC)ccc21 +COc1ccc(CC2CCN(C(=O)c3cnc(C)cn3)CC2)cc1 +O=C(Cc1ccc(Cl)cc1)N1CCn2cnnc2C1 +CNc1ncc(S(=O)(=O)N2CCC(C)CC2C)cn1 +Cc1ccc(NC(=O)CCCC(=O)Nc2ccc(C)cn2)nc1 +CCCCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CCC +O=c1ccc(Br)cn1Cc1noc(-c2cccs2)n1 +N#CCCSc1ccccc1NC(=O)COc1cccc(F)c1 +CC1CCN(C(=O)NCc2cccc(C(N)=O)c2)CC1 +COc1ccc(NC(=O)c2ccccc2C(F)(F)F)cc1OC +COC(=O)c1c(C)[nH]c(C(C)=O)c1-c1ccccc1 +CN1CC(C(=O)NCC2(c3ccc(F)cc3)CCC2)CC1=O +CN(C)C(=O)C1CCCN1c1nc(-c2cccnc2)nc2ccccc12 +CCN(CC)S(=O)(=O)NCc1ccc(-n2nc(C)cc2C)nc1 +Cn1c(COc2cccc(Oc3ncccn3)c2)cc(=O)n(C)c1=O +CN(C(=O)c1cc2cnc3[nH]ccc3c2n1C)c1ccccc1 +Cc1nc2n(n1)C(CC(=O)Nc1cccc(F)c1)C(=O)N2 +O=C(COc1cccc(Cl)c1)Nc1nnc(C2CC2)s1 +CC(C)(C)C(=O)NCC(=O)N1CCC(CO)CC1 +Cc1ccnc(NC(=O)CCS(=O)(=O)c2ccc3c(c2)CCC3)c1 +O=C(CCCc1nc2ccccc2c(=O)[nH]1)OCC1CCCCO1 +CN(C)C(C(=O)Nc1cc(Cl)c(N)c(Cl)c1)c1ccccc1 +O=C(c1cnn2cccnc12)N1CCCC1c1cccs1 +O=c1[nH]ncc(NCc2ccc(-n3ccnc3)nc2)c1Cl +CCCC(=O)Nc1ccc(-c2csc(C3CC3)n2)cc1 +N#CC(C(=O)c1nnn(-c2ccc(F)cc2)c1C1CC1)c1ccccn1 +NC(=O)c1cc(S(=O)(=O)NC2CCCC2)ccc1Cl +Cc1cc2c(c(C(O)c3ccc(Cl)cc3)c1)NC(=O)C2C +COc1cc(C#N)ccc1OCc1nnc(-c2ccc(F)cc2)o1 +COc1cccc(CNC(=O)CCOC(C)C)c1 +Cc1ccc(S(=O)(=O)NC(C)c2ccncc2)c2cccnc12 +CCOCC(=O)N1CCC(n2c(-c3ccoc3)nc3cccnc32)C1 +Cc1cc(C(=O)N2CCC(C)CC2)ccc1NC(=O)C1CC=CC1 +Cc1cccc(C)c1NC(=O)Cc1coc2ccc(F)cc12 +CCc1nc(C)sc1CNC(=O)C1CCc2ccccc2O1 +Cc1nc(C)c(C(=O)N2CCC(Oc3cccnc3)CC2)s1 +Cc1cc(C)cc(NC(=O)CCNC(=O)c2ccoc2)c1 +O=C(CC1(O)C(=O)Nc2ccccc21)c1ccc(O)cc1O +CCC(C(=O)Nc1cccc(C#N)c1)n1cccc(C)c1=O +O=C1CCCC(=O)C12Cc1ccc(Cl)cc1N1CCCCC12 +COC(=O)c1cccc(NC(=O)NCc2ccoc2)c1 +CCc1noc(CCCC(=O)N2CCCCC2Cn2cccn2)n1 +COc1cccc(CNC(=O)C(C)OC(C)=O)c1 +COC(=O)c1cccc2c1CCCN2Cc1ccc(C(N)=O)cc1 +CCNc1ncc(C(=O)N2CCCN(c3ccccc3C)CC2)cn1 +COc1ccccc1OC1CN(c2ncnc3sc(C)cc23)C1 +COc1ccc(NC(=O)N2CCN(c3c(C)n[nH]c3C)CC2)cc1 +Cc1ccc(-c2nnc(COc3ccccn3)o2)cc1 +CC(=O)N1CCN(C(=O)COc2ccc(Cl)cc2)CC1 +COc1ccccc1CCC(=O)Nc1ccccc1C(=O)NC1CC1 +NC(=O)c1ccc(NC(=O)CNC(=O)c2ccccc2Cl)cc1 +CC(=O)c1ccc(NC(=O)c2cn(-c3ccccc3)nc2C)cc1C +O=S(=O)(NCCCOC1CCCC1)c1cccc(F)c1 +CC(C)c1nc(C(C)NC(=O)Cc2cccc(F)c2)cs1 +CNC(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1 +CNC(=O)N1CCC2(CC1)Nc1cc(F)ccc1-n1cccc12 +Cc1nn(Cc2ncc(-c3ccccc3)o2)c(=O)c(C#N)c1C +CC(COc1ccccc1)NC(=O)c1ccc(=O)[nH]c1 +Cn1c(C(=O)NCc2ccco2)cc2sccc21 +COc1cccc(CNC(=O)Nc2nc(C)cs2)c1OC +COc1ccc(CNc2ncc3c(=O)[nH]ccc3n2)cc1 +COc1ccc(C)c(NS(=O)(=O)c2ccccc2)c1 +Cc1noc2ncc(C(=O)N3CCN(CCO)CC3)cc12 +Cc1cc(=O)c2cccc(F)c2n1CC(=O)Nc1cccnc1 +Cc1ccc(S(=O)(=O)N(C)Cc2ccc(C#N)cc2)cc1 +O=C(Nc1ccc(Cl)cn1)C1CC1c1ccccc1F +Cc1occc1-c1nnc(SCCCCC(N)=O)n1C +O=C(Nc1ccccc1C(=O)NCCCO)c1ccsc1 +CCOC(=O)c1[nH]c2ccccc2c1NC(=O)CN1CCOCC1 +COc1ccc(CCNC(=O)C(N)c2ccccc2)cc1OC +O=C1NCCN(C(=O)C2CCCC2)C1c1ccccc1 +Cc1n[nH]c(C)c1NC(=O)COc1ccc(C(F)(F)F)cc1 +O=c1ccc(C2NCCc3cc(Cl)c(O)cc32)n[nH]1 +CC(=O)NCCNC(=O)CCNC(=O)c1ccc(F)cc1F +O=C(CCCc1nc2ccccc2s1)Nc1nccs1 +CCc1nc(C(=O)N(C)C)nn1-c1c(Cl)cccc1Cl +CCNc1nccc(-c2cnn(-c3ccccc3F)c2)n1 +Cc1ccc(N(CC(=O)N(C)c2ccccc2)S(C)(=O)=O)cc1 +COc1ccc(Br)cc1S(=O)(=O)Nc1ccnn1C +CSc1nc(C)c(CCC(=O)N(C)CCC(F)(F)F)c(C)n1 +Fc1cccnc1NC1COC2(CCN(Cc3cccs3)C2)C1 +COc1ccc(C)cc1-c1cc(C)c2nc(N)nn2c1 +CCOC(=O)c1sc2nc(C)nc(N3CCOC(C)C3)c2c1C +Cc1cc(C)n(-c2ccc(C(=O)N3CCCCC3CC(N)=O)cn2)n1 +Cc1nc(CC(=O)Nc2cccc(C(C)C)c2)cs1 +CC(CC(C)(C)c1ccccc1)NC(=O)NC1CC1 +C=CCOc1c(CN2CCOC(C)(c3ccccc3)C2)c(C)nn1C +CC=CCCNC(=O)NCC1CC(=O)N(C2CC2)C1 +NC(=O)C1CCC(CNC(=O)c2cccc(OCC(F)F)n2)CC1 +Cc1nc(C)c(C(=O)N2CCCC2(C)C(=O)NC2CCCC2)s1 +CNC(=O)c1cnc2n1CCN(C(=O)c1ccc3c(c1)OCO3)C2 +Cc1cc(Br)c2[nH]c(C)cc(=O)c2c1 +C#CCN1CCN(C(=O)NCc2cccc(C)c2)CC1 +CC1CCN(C(=O)CCc2nc(-c3nc[nH]n3)no2)C2CCCCC12 +Cc1cc(C)cc(CCNC(=O)C(C)NS(C)(=O)=O)c1 +COc1ncccc1N(C)C(=O)c1ccc(-n2ccnn2)cc1 +COc1cc(C(=O)Nc2ccccc2OC)ccc1O +CC1CCN(S(=O)(=O)C2=CC3=C4CCCCC4=NC3C=C2)CC1 +CC(=O)N1CCC2(O)CCN(C(=O)Cc3cc(C)ccc3C)CC2C1 +CC(=O)c1ccccc1NC(=O)c1ccc(-n2nc(C)cc2C)cc1 +COCCCCN1CCN(S(N)(=O)=O)CC1 +CN(CC(O)C1CC1)C(=O)c1ccc2c(c1)[nH]c(=O)n2C +CCc1noc(CC)c1CNC(=O)NCCc1ccc(F)cc1 +Cc1cc(C)n(CCC(=O)NCCc2cc(=O)[nH]c(C)n2)c(=O)n1 +O=C(Cn1ccccc1=O)Nc1cc2c(cc1Cl)OCCO2 +O=C(NCCc1ccc(F)cc1)c1nc(-c2cccs2)no1 +Cc1nn(C)cc1C(=O)OC(C)C1CCCCC1 +CC(C)c1ccc(C=c2sc3nc(=O)cnn3c2=O)cc1 +CCOc1ncccc1C(=O)NC(C(=O)NC)c1ccc(F)c(F)c1 +Cn1ccnc1SCC(=O)Nc1ccc(F)cc1F +O=C(c1ccccn1)N1CCCn2nc(-c3cccs3)cc2C1 +CCCNC(=O)CNC(=O)NCc1cn(-c2ccccc2)nn1 +COc1ccc(OC)c(C(=O)N2CCN(CCO)CC2)c1 +O=C(Nc1ccc(N2CCCCC2)cn1)c1scnc1C1CC1 +COc1ccccc1-c1nnc(NC(=O)CCOc2ccccc2)o1 +O=C(Nc1nccs1)C1(c2ccccc2)CC1(Cl)Cl +Cc1cc(-c2cc(S(=O)(=O)NCCC(C)C)c(C)s2)on1 +COCc1ccccc1CNC(=O)CSc1cccc(C#N)c1 +CCN(Cc1ccco1)C(=O)Nc1ccc(F)cc1Cl +CCc1ccccc1N1CC(C(=O)N2CC(C)OC(C)C2)CC1=O +COc1ccc2nc(NC(=O)c3ccc(OC(C)=O)cc3)sc2c1 +CNC(=O)C1CCC(NC(=O)CNS(C)(=O)=O)CC1 +CCOc1ccc(C2=CCN(C(=O)C(C)OCC)CC2)cc1 +COCc1ccc(C(=O)N2CCCC(C(=O)N3CCOCC3)C2)o1 +O=C(CCC1CCCC1)N1CCCC(n2cccn2)C1 +CC(=O)c1csc(NC(=O)CC(C)C(C)(C)C)n1 +N#Cc1cnc(Nc2nc3ccccc3s2)nc1N +O=C(c1ccc(C2OCCCO2)cc1)c1cccs1 +O=C(CN1CCN(c2nccs2)CC1)NCCc1ccsc1 +CN(C)C(=O)COCC1CN(Cc2ccccn2)Cc2nnn(C)c21 +O=C1CC(c2nc3ccccc3[nH]2)CN1c1cccc2c1OCO2 +CCC(C)C(=O)NCC(=O)Nc1nc2c(s1)CCC2 +O=C(c1cc(-c2ccc(F)cc2)no1)N1CCCC1c1ccco1 +CC(C)(C)OC(=O)NCCC(=O)Nc1cccc(Cl)c1F +CCOC(=O)c1c(C)c(C(=O)NCc2ccc(C)cc2)c(C)n1CC +CC(=O)N(C)c1cccc(NC(=O)N(C)C(C)c2ccco2)c1 +O=C(NCC1CCCO1)N1CCC(c2nnc3ccccn23)CC1 +CC(NS(C)(=O)=O)C(=O)N(C)C(C)C(C)(C)C +Cc1ncsc1C(=O)NCc1cccc(F)c1 +Cc1ccc(CNC(=O)c2snc(-c3ccc(F)cc3)c2N)o1 +O=C(c1ccc(-n2cnnc2)cc1)N1CCCC(n2cccn2)C1 +COC(CNC(=O)CC1CCCC1)c1cccc(F)c1 +Cc1noc(C2CCCN(c3ccc(C#N)cn3)C2)n1 +CC(CC#N)N(C)C(=O)c1ccc(CSc2nccn2C)o1 +C=CCOCc1nn(C(C)C)c2c1CCN(c1nccs1)C2 +Cc1cc(Cl)c(S(=O)(=O)N(C)C)cc1OCC(N)=O +CCc1oc2c(Cl)cc(-n3cnnc3)cc2c1C +O=C(Cn1cnnn1)N1CCC(c2cccc3ccccc23)CC1 +CC(=O)c1ccccc1NC(=O)c1ccc(S(C)(=O)=O)cc1 +OCc1nnn(-c2cccc(Cl)c2)c1-c1ccccc1F +Nc1ccc(C(N)C(F)(F)F)c(Cl)c1Cl +O=C(Nc1ccc2nc(C3CC3)[nH]c2c1)c1cccc(F)c1 +COc1cccc(OC2CN(C(=O)Cn3cccnc3=O)C2)c1 +NC(=O)CN(C(=O)C1CC(=O)N(Cc2ccccc2)C1)C1CCCC1 +Cc1cccc(CN2CCN(C(=O)COc3ccc(C#N)cc3)CC2)c1 +CCC(CC)C(=O)Nc1ccc(F)cc1C#CCO +CC1=NC(C(F)(F)F)(C(F)(F)F)C(C#N)C(C)=N1 +Cc1nc(CN(C)C(=O)Nc2ccc(F)c(F)c2)cs1 +CCNc1nc(N2CCCC2)nc(-n2cnc(SCC(N)=O)n2)n1 +CCCC(=O)Nc1cccc(C(=O)NCc2cccnc2)c1 +COc1ccc(S(=O)(=O)N(C)C2CCCCC2O)cc1F +O=C(CCc1ccc(Cl)cc1Cl)NC1CCCNC1=O +COC(=O)c1c(C)[nH]c(C(=O)OCc2ccccn2)c1C +N#CCOc1cccc(CC(=O)Nc2ccccc2-c2ccncc2)c1 +CNC(=O)Cn1ccc(-c2cccc(-c3nccc4occc34)c2)n1 +COc1ccc(Cc2nc(C(C)=O)cs2)cc1Cl +COc1cccc(COc2coc(C(=O)NC3CCCC3)cc2=O)c1 +CCOc1ccc(-n2ccn(CC(=O)OC)c(=O)c2=O)cc1 +O=C1Cc2cc(NC(=O)c3cnc(Cc4ccccc4)s3)ccc2N1 +CCc1nc(COC(=O)C2(c3ccccc3)CC2)cs1 +CC(=O)c1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +CCOc1ccccc1CNC(=O)Nc1ccccc1N(C)C +COc1ccc(CC(=O)Nc2c(C)cc(C)cc2C)c(OC)c1 +CC(=O)Nc1ccc(OC(=O)CCOC(C)C)cc1 +CCOc1cc(F)ccc1NC(=O)COc1ccc(C#N)cc1OC +Cn1cnnc1CNC(=O)c1csc(-c2ccc3c(c2)OCO3)n1 +CCn1ccnc1SCC(=O)c1cnn(-c2ccccc2)c1 +COC(=O)C(NC(=O)c1csc(-c2ccc(OC)cc2)n1)C(C)C +NC(=O)NCCCCC(=O)Nc1ccccc1O +C=CCc1c(C)nn(C(=O)c2ccc(C)cc2)c1C +CC(C)N(C)C(=O)c1cnn(-c2ccc(Cl)cc2Cl)c1 +O=C(COc1ccccc1Cl)Nc1onc2c1CCCC2 +CCOCCn1cnc2sc(C(=O)NC(C)CC)c(C)c2c1=O +CCC1CCCC(NC(=O)N2CCN(c3ncccn3)CC2)C1 +Cc1cc(=O)c(C(=O)NC(C)(C)C)nn1-c1ccccc1F +Cc1ccc(CC2(c3ccc(C)c(C)c3)NC(N)=NC2=O)cc1 +CC(=O)c1cc2c(cc1NC(=O)c1ccsc1)OCO2 +CC(C)Oc1ncnc(Nc2ccccc2Br)c1N +CSc1cccc(NC(=O)N(C)Cc2nccn2C(F)F)c1 +O=C(Nc1cc(C(F)(F)F)ccc1F)c1ccncc1 +CCN(CCO)C(=O)c1ccc(CNC(=O)c2cccs2)cc1 +O=C(CCCc1cc(F)ccc1F)NCCn1cccc1 +Cc1ccc(CNS(=O)(=O)c2cccc(Cl)c2)s1 +Cn1cc(C2CN(Cc3c[nH]nc3-c3cccnc3)CCO2)cn1 +CCNS(=O)(=O)c1ccc(NC(=O)c2cccc(F)c2)cc1 +Cc1cccc(COC2CN(Cc3cccs3)C3CCCOC23)n1 +O=C(c1cc2ccccc2[nH]1)N1Cc2cncnc2C1 +CC(C)(C#N)NC(=O)c1cn(Cc2cccc(F)c2)nn1 +Cn1cc(NS(=O)(=O)c2c(Cl)cccc2Cl)cn1 +CC1CC(c2ccsc2)CN1C(=O)COc1ccc(CC#N)cc1 +CCOc1cccc(NC(=O)N2CCN(c3nccs3)CC2)c1 +CC(C)C(NC(=O)C1CC1c1ccccc1OC(F)(F)F)C(N)=O +Cc1nc2ncc3c(=O)n(-n4c(C)nnc4C)ccc3n2n1 +CC1(C)CC(=O)c2cc(C(=O)Nc3ccccc3C#N)c(=O)[nH]c2C1 +O=C(c1ccncc1)N(Cc1ccccn1)C1CC1 +Cc1ccn2c(=NC(=O)Cc3coc(-c4cccs4)n3)[nH]nc2c1 +O=C(OCC#Cc1ccccc1)C1CCCN1C(=O)c1cccs1 +C=CCOc1cc(C)nc2cc(C3CCOCC3)nn12 +O=C(NC1CC1)c1ccc2onc(-c3coc(-c4ccccc4)n3)c2c1 +CCOC(=O)c1cnn(-c2ccc(Cl)cc2Cl)c1N +Cc1[nH]ncc1CCCNC(=O)c1cc2c(cc1O)OCO2 +COCCCOc1ccc(C(=O)NC2C3CCOC3C2(C)C)cn1 +CC(=O)NC(C(=O)NCc1cscn1)C(C)C +O=C(CSc1ncccn1)Nc1ccc(SC(F)F)cc1 +CCOc1ccccc1NC(=O)c1cc(C)nn1CC +CCc1c(C)sc2ncn(Cc3ccc(C#N)cc3)c(=O)c12 +Cc1ccc(C(N)C(=O)NCC2CCCO2)cc1F +CCC(C)N(C)C(=O)NCCN1CCN(c2ncccn2)CC1 +CCOc1cc(-c2nc(-c3ccoc3C)n[nH]2)ccc1O +CCOCc1ccccc1CNC(=O)c1cn[nH]c1 +Cc1nn(C)c2cnn(CCNC(=O)C3CCCO3)c12 +CCc1ccc(C(=O)CCC(=O)N2CCCS2(=O)=O)cc1 +O=C(C1CCCO1)N1CCN(C2CCN(c3ccccc3)C2=O)CC1 +CCOc1ccc2nc(C(=O)NCc3cc(C)ccc3C)cn2n1 +COc1ccccc1OCCC(=O)Nc1ccnn1C(C)C +CCN(C1CC1)S(=O)(=O)c1ccc(NC(C)=O)cc1 +Cc1nn2cnnc2c(C)c1CCC(=O)Nc1nncs1 +Cc1ccc(OCC(=O)N(C)C2(C#N)CCCC2)cc1 +CNC(=O)C(CC(C)C)NS(=O)(=O)c1ccc(F)cc1F +CCNC(=O)NC1(C(=O)Nc2cccc(OCC)c2)CCCC1 +CCN(CC)C(=O)CSc1nc(C2CC2)nc2ccccc12 +Cc1nnc(SC2CCCc3ccccc32)n1CC(N)=O +CCCCOc1cccc(CNS(N)(=O)=O)c1 +CC(C1CC1)N(C)C(=O)NC1CC(=O)N(C)C1c1ccc(Cl)cc1 +O=C(Cc1nc(CO)cs1)Nc1nccs1 +CC(C)(C)CC(=O)N(CCC#N)c1ccc2c(c1)OCCO2 +Cc1ccccc1Oc1ncc(Br)cn1 +COc1cc(C(=O)N2CCC(C)CC2)cc2c1OCCO2 +Cn1nc(CC(=O)Nc2ccccc2)c2ccccc2c1=O +CC(C)S(=O)(=O)NCCNC(=O)c1ccoc1 +O=C(Nc1cnc2n1CCCC2)c1ccccc1-n1cncn1 +COC(CNS(=O)(=O)Cc1cccc(F)c1)c1ccc(C)s1 +Cn1nc(C(=O)Oc2cc(Cl)ccc2Cl)ccc1=O +CCC(C)NC(=O)CCc1c(C)nc2nc(N)nn2c1C +CNC(=O)c1cccc(CNc2ccccc2Cl)c1 +Cc1nc(N2CCC(n3cccc3)CC2)c2c3c(sc2n1)CCC3 +Cc1nn(-c2ccc(C(=O)NCc3cccnc3)cn2)c(C)c1C +COc1ccc(C(=O)NCc2nncn2C)cc1-c1ccccc1 +CCc1cnc(N(C)Cc2cnc3ccccn23)nc1 +COC(=O)c1ccc(CN2CCOCC2C2CC2)c(F)c1 +Cc1cccc(S(=O)(=O)N(C)C(C#N)c2cccs2)c1 +CCn1ccc(C(=O)N2CCCC2c2cccc(C)c2)n1 +Cc1csc(=O)n1CC(=O)NC(C)CCCC(C)C +CCOC(=O)c1cnn(C2CCCN(C(=O)c3cc(C)c(C)o3)C2)c1 +COc1cc(C)c(CNC(N)=O)cc1C(C)(C)C +CC(C)N(Cc1ccc(C#N)cc1)C(=O)c1ccsc1 +COc1ccc(-n2c(C)c(C(C)=O)c(C(C)=O)c2C)cc1 +CCc1cnc(NC(=O)N2CC(C)CCC2C)s1 +CN(C)c1nc2sc(C(=O)NCc3ccsc3)cc2s1 +CC(C)n1cnnc1C1CCCN(S(=O)(=O)c2c[nH]cn2)C1 +CC(=O)c1c(C)[nH]c(C(=O)N(C)CCOCC2CC2)c1C +CC(=O)N1CCN(C(=O)c2ccc(OCC(F)F)nc2)CC1 +COc1cc2ccccc2c(Br)c1O +Cc1nnc(SCCCc2nc3ccccc3o2)n1N +Cc1ccc(C(=O)c2ccccc2C(=O)NCc2ccncc2)cc1C +CN(CC1COc2ccccc2O1)C(=O)c1ccc(NCCO)nc1 +COc1ccc(NC(=O)c2ccc(NC(=O)CC#N)cc2)cc1Cl +O=C1OCCC1NS(=O)(=O)c1ccc(C(F)(F)F)cc1 +O=C1COc2cc(C(=O)NCc3ccc(O)cc3)ccc2N1 +CC(COc1cccc(C#N)c1)OC(=O)c1ncoc1C(C)C +COc1ccc2nc3c(cc2c1)c(NC(C)=O)nn3CC(C)C +Cc1nc(CC(=O)N(C)c2cccc3ccccc23)cs1 +CCc1ccccc1OC1CN(Cc2ccncc2)C1 +O=C(c1ccc(Br)c(-n2cnnn2)c1)N1CCOCC1 +COc1ccc(OC)c(CNC(=O)c2csc(C)n2)c1 +COc1ccc(Cc2nc3cc(O)ccc3o2)cc1OC +CC(C)n1nc(-c2ccccc2Br)c2c1CCNC2 +CCn1c(=O)c2c(nc(NCCCO)n2C)n(CC)c1=O +CCCc1noc(CN2CCCC(c3nc(C)no3)C2)n1 +Fc1ccc(C(NCc2nnc3ccccn23)c2ccccc2)nc1 +CS(=O)(=O)N1CCC(c2nc3ccc(C(F)(F)F)cc3[nH]2)C1 +CCC(CC)N(CCO)C(=O)c1cc(C)ccc1C +Cc1nc(-c2ccncc2)sc1C(=O)c1cccc(N)c1 +CCOC(=O)CC(C#N)c1cc(OC)ccc1OC +O=C1C(c2ccccc2)Nc2cc(F)ccc2N1CCCO +COC(=O)c1ccc(Cn2ccc(=O)c3cc(Cl)ccc32)o1 +CCn1c(NCC(=O)NC(C)C)nc2sc3c(c2c1=O)CCCC3 +CN(c1nccs1)S(=O)(=O)c1ccc(OCC(F)F)cc1 +CN(C)S(=O)(=O)N1CC(S(=O)(=O)c2ccc(Cl)cc2)C1 +C=CCN(CC=C)C(=O)c1onc(S(=O)(=O)CC)c1N +O=C(NCCOc1cccc(Br)c1)NCC1CCOC1 +CCC(NC(=O)NCc1nncn1CC)c1cccs1 +COc1ncccc1CNC(=O)NCC1(c2ccccc2)CC1 +CCCNC(=O)c1csc(NCc2ccc(OC)cc2)n1 +COC1=NC(C(C)C)C(OC)=NC1Cc1cc(F)ccc1F +CC1=C(C(=O)NCC(C)c2nc(-c3ccccc3)no2)CCCO1 +CC(C)(CNC(=O)Nc1nccs1)c1ccc2c(c1)OCCO2 +COCC1(C(=O)NC(c2ccncc2)c2ccc(C)cc2)CCC1 +Cc1cc(C(=O)N(CCC#N)Cc2ccco2)ccc1S(N)(=O)=O +CCN(Cc1ccoc1)C(=O)Nc1ccc2cnn(CCOC)c2c1 +CCNC(=O)c1ccc(CNC(=O)NC(C)CC)cc1 +CCOc1c(O)ccc2c1C(C(C)NC(C)=O)NCC2 +CN(CCc1ccccn1)C(=O)c1ccc(-n2cncn2)cc1 +O=C(COC(=O)c1ccco1)Nc1ccc(OC(F)F)cc1 +COC(C)C(=O)Nc1cccc(C(=O)NCc2ccccc2)c1 +Cc1ccc(C(=O)CCC(=O)Nc2ccn(Cc3ccncc3)n2)cc1 +CCOC(=O)CN(C)C(=O)CSc1ccccc1F +Cc1ccc2c(=O)cc(C(=O)NCc3ccncc3)oc2c1C +NC(=O)C1CCN(C(=O)Cn2ncc3ccccc32)c2ccccc21 +Nc1ccc(F)cc1S(=O)(=O)NCCc1nccs1 +Fc1cc2c(c(F)c1F)CCNC2C1CCOCC1 +CCc1nc(Cn2c(=O)oc3ccccc32)cs1 +O=C(Nc1cc(F)cc(N2CCCC2)c1)c1ccccn1 +CCCCN(CC)C(=O)c1cccc(NC(=O)C2CCCO2)c1 +Cc1nc(-c2noc3ccc(C(=O)Nc4cccnc4)cc23)cs1 +Cc1csc(NC(=O)C(C)Sc2ccccc2Cl)n1 +CN(C)c1ccnc(CNC(=O)c2ccccc2C(F)(F)F)n1 +Cc1cccc(C)c1NS(=O)(=O)c1ccccc1O +O=C1NCCCCC1Sc1nnnn1CC(F)(F)F +Cc1nn(C)c(=O)c(C(=O)NCc2ccc(C(=O)N(C)C)cc2)c1C +Cc1nc2c(c(=O)[nH]1)CCN(C(=O)c1cccc3nccnc13)C2 +Cc1cccc2ncc(C(=O)NCC3=CCCCC3)c(=O)n12 +CC(CCNC(=O)NC(C)c1ccncc1)c1ccccc1 +O=C(Nc1cc(-n2ccnc2)ncn1)c1cccc(C(F)(F)F)c1 +Cc1cnc(C(=O)Nc2ncc(Cc3ccc(C)c(F)c3)s2)cn1 +CNc1ccc(NS(=O)(=O)c2cccc(C)c2)cc1C +COc1ccc(OCCCNC(=O)c2cnc3[nH]nc(C)c3c2)cc1 +CNC(C(=O)OC)c1ccccc1Br +CCOc1cc(CCC(O)c2cccnc2)ccc1O +COC(=O)c1ccc(NCc2ccccn2)cc1O +CCOC(=O)C1CCN(C(=O)CNc2cc(C)cc(C)c2)CC1 +Cc1ccnc2nc(C(=O)Nc3nc4c(s3)CCCCC4)nn12 +O=C(Cc1cccc(F)c1)Oc1ccc(NC(=O)C2CC2)cc1 +CCC(C)N1CC(C(O)c2cccs2)CC1=O +N#Cc1ccc(NC(=O)CCCc2nc(-c3ccccc3)no2)cc1 +NC(=O)CSc1nnc(N2CCCC2)n1-c1ccccc1Cl +Cc1cc(C)c2nnc(C(=O)NC3CCCCC3)n2n1 +COc1ccccc1Oc1ccc(NC(N)=O)cc1 +CCCC(=O)N1CCCC1C(=O)NC1CCCCC1C +CC(=O)Nc1ccc(O)c(C(=O)NC2CCc3c(O)cccc32)c1 +CCN(CC)C(=O)CCC(=O)N(C)C(C)c1ccccc1Cl +Cc1noc(C)c1CN(C)C(=O)CCc1nc(-c2ccccc2)no1 +Cn1nnnc1SCC(=O)NC1(C#N)CCCCC1 +Cc1cc(=O)oc2c3c(ccc12)OCN(C(C)C)C3 +COc1cccc(COC(C)C(=O)Nc2cc(F)ccc2OC)c1 +CC(=O)NCC(=O)N1CCC2(CCCN(CC3CCCCC3)C2=O)C1 +CC(C)COc1cccc(C(=O)NCC2CN3CCCCC3CO2)c1 +COCCNC(=O)CCNC(=O)Nc1ccccc1Br +COC(=O)c1cc(=O)c2cc(NC(=O)c3cccnc3)ccc2o1 +COc1cccc2cc(C(=O)Nc3cnn(Cc4ccccc4)c3)oc12 +c1ccc2c(c1)CCCc1cc(NCCN3CCOCC3)nnc1-2 +O=C(Cc1ccc2ccccc2c1)N1CCOCC1 +CCOC(=O)CSc1ncnc2c1cnn2-c1ccc(F)cc1 +CCC1CCc2sc(-c3nnc(SCC(N)=O)n3C)cc2C1 +CNc1cc(C(=O)NCC2COc3ccccc3C2)ccn1 +CC(=O)c1ccccc1OCC(O)Cn1ccnc1C +CC(CNc1nc2ccccc2c(=O)[nH]1)Cn1cccn1 +O=C(NCC1CCCO1)c1ccc2c(c1)nc1n2CCOC1 +Cc1ccc(N2CC(C(=O)NCC3CCCO3)CCC2=O)cc1C +CCOc1ccccc1NC(=O)COC(=O)c1cnccn1 +COC1COC2C(NC(=O)NCc3ccccc3)COC12 +NC1=NC(=O)C(Cc2cccc(Cl)c2)(c2ccc(F)cc2)N1 +CCCC1CCC(NC(=O)c2ccc(NC(C)=O)cc2)CC1 +Cc1ccc(NC(=O)c2ccc(S(=O)(=O)NC3CC3)cc2)cc1 +CC(C)Oc1ccc(CNC(=O)c2scnc2C2CC2)cc1 +CC(C)c1ccsc1C(=O)NCc1cccs1 +CCOC(=O)Nc1ccccc1C(=O)N1CCCCC1 +O=C(Nc1ccc(Cl)cc1)c1ccc2nncn2c1 +COc1cccc(C2(CNC(=O)NCc3ncn(C)n3)CCCC2)c1 +O=C(NCCn1ccc2cc(Br)ccc21)c1cccnc1 +O=C(c1ccc(F)cc1F)N1CCN(Cc2ccsc2)CC1 +Cn1ccnc1-c1c(Br)ccc(F)c1F +C=CCn1nc(C)c(CCC(=O)NCC2CCCO2)c1C +CCOCCC(=O)Nc1cc(C#N)ccc1Cl +CC(Cc1ccc(O)cc1)NC(=O)Nc1ccncc1 +OCCc1ccccc1-n1ccnc1-c1ccccc1Cn1cccn1 +CCCN(CCC)C(=O)C1CC(=O)N(Cc2ccccc2F)C1 +O=C(NC1CCC(n2cnnc2)CC1)c1ccc(C2CCCO2)s1 +CC1CCCCN1C(=O)COC(=O)c1nccnc1N +CCN(Cc1cccs1)C(=O)c1ccc(SC)cc1 +CCN(Cc1cccc(C)c1)C(=O)COc1ccc(C(C)=O)cc1 +Cc1cccc2c(CC(=O)N(C)CCOCC3CC3)c[nH]c12 +O=C(CNC(=O)Nc1ccccc1N1CCCCCC1)NCC1CC1 +O=C(NCCS(=O)(=O)NCc1ccccc1)NC1CC1 +CC(NC(=O)c1cccs1)C(=O)Nc1ccc(-n2ccnc2)nc1 +O=C(c1ccc(C#CCO)cc1)N1CCC(O)CC1 +O=C(Cn1cccn1)NCc1ccnc(Oc2ccc(F)cc2)c1 +O=C(NCCc1cccc2cccnc12)c1cc2c(s1)CCC2 +NS(=O)(=O)CCNC(=O)c1cccc(C#CCO)c1 +Cc1sc2ncnc(N3CCc4sccc4C3)c2c1C +CCS(=O)(=O)NCc1c(OC)cc(OC)cc1OC +O=C(NCc1cccnc1OCC(F)(F)F)c1ccc(=O)[nH]c1 +COc1cc2[nH]c(=O)n(C3CC3)c(=O)c2cc1OC +CC(Oc1ccccc1Cl)C(=O)OCC1CCC(=O)N1 +N#Cc1ccc(NCCC(=O)c2ccc(F)cc2)cc1 +CCCNC(=O)c1cccc(C(=O)Nc2nc3ccccc3s2)c1 +Cc1occc1C(=O)N1CCC2OCCCC2(COCC2CCC2)C1 +CCOC(=O)CNC(=O)NCC(=O)N1CCc2ccccc21 +O=C(CN1C(=O)CCCc2ccccc21)Nc1cccc(F)c1 +CCc1c(C)nn(C(=O)COc2ccccc2OC)c1C +CN(Cc1ccccc1C(F)(F)F)C(=O)CCN1CCCC1=O +O=C(CN1CCOCC1)N1CCN(CC2(O)CCCCC2)CC1 +CC(c1ccccn1)N(C)C(=O)CNC(=O)c1cccc(O)c1 +COCCCNS(=O)(=O)c1ccc(Br)c(C)c1 +CCCCc1nnc(NC(=O)c2ccc(-n3cncn3)nc2)s1 +COC1CCN(C(=O)NCCc2ccccc2F)CC1 +CCCn1cc(C(=O)NC2CCc3[nH]ncc3C2)c(C)n1 +O=C(NC1CCN2C(=O)c3ccccc3NC(=O)C12)C1CCCC1 +CCC(=O)Nc1nn(CC)c2nc3ccccc3cc12 +Cc1ccc(S(=O)(=O)N2CCN(c3ccc(C#N)cc3)CC2)cc1 +CSc1cccc(NC2C(=O)Nc3ccccc32)c1 +CCOCC(=O)Nc1cc(F)c(OC(C)(C)C)c(F)c1 +CC(=O)c1ccc(C(=O)N2CCCC2C2CCCC2)cc1 +O=C(NCCc1ccc2c(c1)OCO2)NCc1cscn1 +COC(=O)C1CN(Cc2c(C)nn(-c3ccc(F)cc3)c2C)CCO1 +Cc1noc(C)c1CC(=O)Nc1ccccc1-n1cnnn1 +O=C(COc1ccc(Cl)cc1)N1Cc2cncnc2C1 +CCn1cc(C(=O)NCc2ccccc2OC)c(C)n1 +Cc1ccn(CCNC(=O)c2nc3ccc(F)cc3[nH]2)n1 +Cc1cc(C)n2c(CN(CCC#N)CC(C)(C)C)cnc2n1 +Cc1ccc(C(=O)Nc2ccc(-n3ccnc3)cc2)c(O)c1C +CC(C)(C)OC(=O)N1CCC(COc2ccncn2)C1 +CC(C)n1nccc1NC(=O)c1ccc(F)c(F)c1 +Cc1ccc(S(=O)(=O)NC2CCC(O)CC2)c(Cl)c1 +Nc1nccnc1C(=O)Nc1ccn(-c2ncccc2Cl)n1 +Cc1ccc2c(C)c(C(=O)NCC(=O)C(C)(C)C)oc2c1 +O=C(Nc1ccc2c(c1)OCCO2)C1(c2ccc(Cl)cc2)CC1 +CN(CC(F)(F)F)C(=O)CSc1ncccc1Cl +CCOC(=O)C1CCCN(C(=O)NCc2ccccc2OCC)C1 +CC(C)(C)OC(=O)n1cc(Br)c2ncccc21 +O=C1CCCc2[nH]c(=O)c(C(=O)NCC3CC3)cc21 +O=C(NCC1CCCO1)Nc1nnc(C2CCCCC2)s1 +CCC(=O)N1CCCCC1C(=O)NCC1CCCC(C)C1 +CC(C(=O)NCCCNC(=O)c1ccc(F)cc1)c1ccsc1 +COc1ccc(S(=O)(=O)N(C)CCC#N)cc1Cl +Cn1cc(CCNC(=O)CCc2cc(F)ccc2F)cn1 +Cc1ccc(=O)n(CC(=O)Nc2ccccc2C(F)(F)F)n1 +NC(=O)c1cnc(NC2CCN(Cc3ccccc3)C2=O)c(Cl)c1 +O=C(NCc1cccc(Cl)c1)c1cnc2snnc2c1 +CCC(Nc1cc(C)nc2ncnn12)c1ccc(Cl)cc1 +COc1cccc(CNC(=O)N2CCCC2c2ccco2)c1 +Nc1cccc(-c2cnnn2-c2nc(-c3ccccc3)cs2)c1 +Cc1ccc(S(=O)(=O)Nc2ccc3oc(=O)[nH]c3c2)s1 +COC(=O)CN(C)C(=O)c1ccc(Cl)c(N)c1 +CN(CCOCC1CC1)C(=O)c1coc2ccccc12 +CCCn1nccc1C(=O)N1CCC(Cc2n[nH]c(=O)n2CC)CC1 +Cc1sc(NC(=O)Nc2cccc(F)c2)c(C#N)c1C +Cc1ccc(O)c(C(=O)NC(C)c2cccnc2)c1 +CCc1oc(C(=O)Nc2ccc3c(c2)COC3)cc1C +COc1cc(OC)cc(C(=O)NCC(=O)NCc2ccccc2C)c1 +Cc1noc(C)c1C(=O)N(C)Cc1csc(-c2cccs2)n1 +CN(C)c1cc(OC2CC2)cnc1S(N)(=O)=O +Cc1ccncc1NC(=O)N1CCC(c2ccn[nH]2)CC1 +CC(Nc1nc(-c2ccsc2)nc2ccccc12)c1nncn1C +CCC(C(=O)Nc1ccncc1C)c1ccccc1 +Cc1cnc(C(=O)N(c2ccccc2)c2nc(C)cs2)cn1 +Cn1ccc(-c2cc(C(=O)N3CCOCC3)c3ccccn23)n1 +CC1(C)CC1(C(=O)N1CCc2c(nc(N)[nH]c2=O)C1)c1cccs1 +CC(C)C(=O)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 +COC(=O)c1cccc(NC(=O)c2cc3ccccn3n2)c1 +c1coc(-c2nc3nccc(-c4ccco4)n3n2)c1 +C=CCNC(=O)c1c(N)n(-c2ccccc2)c2nc3ccccc3nc12 +NC(=O)c1ccc(C#CCNC(=O)c2cccnc2)cc1 +Cc1cccc(C)c1OC(=O)Cn1nc(C)c(Cl)c1C +C=CCn1c(N)nnc1SC(C(=O)NC(C)C)c1ccccc1 +Cc1cc(F)ccc1NCc1ccc(OCC(N)=O)cc1 +Cc1cnc2c(S(=O)(=O)NC3CCCn4ncnc43)cccc2c1 +O=c1ccc(-c2ccc(Br)cc2)no1 +CC(=O)Nc1ccc(CNS(=O)(=O)c2cccc(C(C)=O)c2)cc1 +CNS(=O)(=O)c1ccc(CNC(=O)c2ccn(C)c(=O)c2)cc1 +Cc1ccc(-n2[nH]c(C(=O)NC3(C)Cc4ccccc4C3)cc2=O)cc1 +CC(C)(C)n1cc(C(=O)Nc2n[nH]c(-c3ccco3)n2)cn1 +CC(NC(=O)COc1ccccc1F)c1ccccc1 +CCCC(C)N(C)C(=O)CNC(=O)NC1CCCCC1 +O=C(C1CCCC1)N1CCN(CC(O)C2CC2)CC1 +CC(NC(=O)COc1ccccc1F)c1ccc(-n2ccnc2)cc1 +CC(C)COC1CCN(C(=O)NCc2nnc3ccccn23)CC1 +Cc1ccc(SC(C)C(=O)NCc2cnn3ccccc23)cc1 +CCCCN1C(=O)COc2ccc(NC(=O)c3csnn3)cc21 +O=C(Nc1ccn(-c2ncccc2Cl)n1)NC1CCCC1 +Cc1ccc(NC(=O)C2CCN(C(=O)NC3CC3)CC2)c(C)c1 +Cc1cc(C)c(CNC(=O)N2CCCC2C(N)=O)c(=O)[nH]1 +CCCn1nc(C)c(NC(=O)NCc2nnc(CC)o2)c1C +COc1ccc(-c2nc(N3CCCC3=O)sc2C)cc1 +Cc1cccc(C(=O)NCCC(=O)NC2(c3ccccc3)CCC2)c1 +Cc1cc(C)n(CCN2CCN(C(=O)CC(C)C)CC2)n1 +COC(=O)C(CNC(=O)Nc1nncs1)Cc1ccc(O)cc1 +N#Cc1cc(F)c(N2CCN(c3ccccc3O)CC2)c(F)c1 +O=C1NCCCCC1Sc1nc(NC2CC2)c2ccccc2n1 +O=C(C1CCOCC1)N1CCCC(O)(C(F)(F)F)C1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)Nc1cn[nH]c1 +Nc1cc(Cl)cc2c1CCN(CCCN1CCOCC1)C2 +COc1cccc2c(=O)c(C(=O)Nc3ccccc3C#N)c[nH]c12 +Cc1ccccc1OCC(=O)OCC(=O)NC1CCCCC1 +COc1cccc(-c2nc(CC(=O)Nc3ccc(F)cc3)no2)c1 +CC1CCC(C)N(C(=O)NCc2ncn(C)n2)C1 +CN(C)C(C(=O)N1CCNCC1)c1ccccc1F +CC(C)CN1CCOC(COC(=O)c2ccc(S(C)=O)cc2)C1 +C#CCCNC(=O)CC(c1ccccc1)c1ccccc1 +CCCC(C#N)NS(=O)(=O)c1sccc1Br +CCc1onc(C)c1NC(=O)c1cccc(N2CCCNC2=O)c1 +COc1ccc(C(C)=O)c(OC(=O)c2cccc(-n3cccn3)n2)c1 +Cc1ccc(-c2n[nH]c(CNC(=O)c3ccco3)n2)cc1 +O=C(Nc1ccc2nn(-c3ccc(F)cc3)nc2c1)c1cccnc1 +CN(C(=O)CCC(=O)c1ccc(F)cc1F)c1nccs1 +CCCn1nc2c(cc1=O)CN(c1nnc(C)c(C)c1C#N)CC2 +CCc1nc(CNc2ccccc2C(=O)NCC(C)C)no1 +CCN(C)C(=O)c1ccc(S(=O)(=O)Nc2cccc(C)c2C)cc1 +Fc1cccc(Nc2nnc(Sc3ncccn3)s2)c1 +O=C(Cc1cccc(O)c1)N1CCc2cc(Br)ccc21 +Cc1cc(-c2coc3ccccc3c2=O)nc(N)n1 +Cc1ccc(C(=O)NCC(=O)N2CCC(O)C2)cc1 +O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]nc1Nc1ccccc1 +O=C(NC1CC1)C1CCN(S(=O)(=O)Cc2ccccc2F)CC1 +O=C(NCc1cc(Cl)ccn1)Nc1ccc(OC2CCC2)c(F)c1 +Nc1nc(C2CC2)ncc1C(=O)Nc1ccc(F)cc1 +c1cc2ncc(N3CCOCC3)nc2cc1-c1cnc2[nH]ncc2c1 +CCn1c(C(=O)c2ccccc2)nc2ccccc21 +CCc1cc(C(=O)N2CCCCC2C)c2c(C)noc2n1 +COc1cc(C)cc(-c2nccc(N3CCC(O)CC3)n2)c1OC +COc1ccccc1CNC(=O)c1noc(C)c1CN1CCOCC1 +C=CCN(CC(=O)OCC)C(=O)c1ccc2c(c1)CCC(=O)N2C +Nc1nonc1-n1nnc(C(=O)N2CCCC2)c1-c1ccccc1 +COC(=O)N1CCN(C(=O)c2ccccc2N)CC1 +NC(=O)CSc1nc2ccccc2n1Cc1c(F)cccc1Cl +COc1ccc2c(c1)nc1[nH]c(Nc3cccc(C#N)c3)nn12 +CC(=O)Nc1sc(-c2ccccc2)nc1-c1ccco1 +CCCCN(C)C(=O)CNc1ccccc1OC +O=C(NCCO)NC(Cn1cnc2ccccc21)c1ccc(F)cc1 +COc1ccc2nnc(C(=O)NCCc3ccccc3)nc2c1 +Cc1noc(C2CN(C(=O)Nc3ccccc3Cl)C2)n1 +O=C(NCCOc1ccc2c(c1)OCO2)c1ccc2ccnn2c1 +CC(=O)NCC(=O)Nc1cc(C(C)(C)C)nn1-c1ccc(C)cc1 +CC(C)(C)CC(=O)Nc1ccc(-c2cc[nH]n2)cc1 +CNC(=O)c1cccc(CCNC(=O)NCC(=O)NC(C)(C)C)c1 +CC12C(=O)N(C3CC3)CC(=O)N1CCc1c2[nH]c2ccccc12 +c1cnn(CCSc2nnc(N3CCCC3)n2C2CC2)c1 +COc1ccc(CCNC(=O)CNC(C)=O)cc1 +CCCOc1ccccc1C(=O)NCc1ccc(S(N)(=O)=O)cc1 +N#Cc1ccccc1S(=O)(=O)N1CCN(CC2CCCO2)CC1 +CNC(=O)c1ccc(Cl)c(NC(=O)CCCOc2ccccc2)c1 +Cc1nc(N2CCOCC2)ncc1C(=O)Nc1cccc(O)c1 +Cc1n[nH]c(SCc2ccc(Cl)cc2N)n1 +CC(Sc1nncs1)C(=O)NC1CCCNC1=O +COC(=O)C1C(C)=NC2=CCCC(=O)C2C1c1cccnc1 +O=C(NCc1ccco1)c1cccc2nscc12 +COc1ccc2ccn(CC(=O)N3CCCC(C(N)=O)C3)c(=O)c2c1 +CCCC(=O)N1CCC(C(=O)NCc2ccc(C#N)cc2)CC1 +O=C(CCc1nc2ncccc2[nH]1)Nc1cccc(N2CCCC2=O)c1 +CC(CN1CCOCC1)NC(=O)c1cccc(Nc2ncccn2)c1 +O=C(c1cnn(-c2ccccc2F)c1)N1CCCC1Cn1cccn1 +Cc1ccc(CC(=O)NC(C)Cc2c(Cl)cccc2Cl)cn1 +CCCCCNC(=O)N1CCN(C(=O)c2ccc(F)c(F)c2)CC1 +CCCC(NC(=O)c1ccnc(-n2ccnc2)c1)c1ccccc1 +CCOC(C)c1noc(CN2CCCC(c3cc(C)n[nH]3)C2)n1 +COc1ccnc(NC(=O)C(C)(C)Oc2cccc(Cl)c2)c1 +CCN(Cc1ccccc1)C(=O)CNc1ncnc2[nH]cnc12 +Cc1ccn(-c2ccc(N3CCCC3CC(O)c3ccccc3)nn2)n1 +O=C(CCCc1nc2cccnc2n1C1CCCCC1)N1CCCC1 +COc1cc(CNC(=O)c2ccc(-n3cncn3)cc2)ccn1 +CC(=O)c1cccc(Nc2ncnc(NCc3cccnc3)c2N)c1 +CCC(=O)Nc1c(C#N)c(C)c(C)n1Cc1cccs1 +Cc1ccc(C(=O)NCC(=O)N(CCO)C2CC2)s1 +Cc1ccc(-n2cc(C(=O)NC(C)C)nn2)cc1C +CC(=O)c1c[nH]c(C(=O)Nc2ccn(-c3ncccc3Cl)n2)c1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1cccc(-n2cnnn2)c1 +CC1CC(C)CN(C(=O)c2cc3cc(F)ccc3[nH]2)C1 +CC(=O)Nc1ccc(S(=O)(=O)NCCc2ccoc2)cc1 +CN(Cc1ccccc1)c1ncc(C(=O)NCc2ccccc2)c(N)n1 +O=C(Nc1cccc(N2CCNC2=O)c1)c1occc1-c1ccccc1 +CCn1cc(O)c(=O)cc1CN(CCO)CCO +CCOC(=O)c1csc(NC(=O)C(C)(C)C)n1 +COc1nn(C)cc1C(=O)N(Cc1ccsc1)C1CC1 +Cc1ccc2cccc(NC(=O)N3CCc4cc(F)ccc4C3)c2n1 +N#Cc1c(-c2ccc(F)cc2F)nn(-c2cccc(F)c2)c1N +CC(O)CN1CC2=C(C1=O)C(c1ccc(O)cc1)NC(=O)N2C +Cc1cc(C(=O)C(C#N)c2nc(-c3c(F)cccc3F)cs2)no1 +CC(C)CC(=O)Nc1ccc2c(c1)nc1n2CCN(C2CCCC2)C1 +O=C(c1cc(Cl)c2c(c1)OCO2)N1CCCC(n2cncn2)C1 +CC(C)C(=O)Nc1ccc(OC(C)C(=O)N(C(C)C)C(C)C)cc1 +C=CCN(c1ccc(C(=O)NC2CC2)cc1)S(C)(=O)=O +Cc1ccccc1C(=O)Nc1ccc(-n2nncc2C)cc1 +Cc1cnn(CC2CCCN2C(=O)COc2cccc(C(N)=O)c2)c1 +Cc1c(C(=O)N2CCCC2CCC(C)C)cnn1-c1ccncc1 +CCOC(=O)C1CCN(C(=O)C2CN(C(=O)c3cc(C)on3)C2)CC1 +CCS(=O)(=O)N1CCCC1c1nnc2n1CCCCC2 +N#Cc1cc(NC(=O)c2c[nH]c3ccccc3c2=O)ccc1F +CN1C(=O)CCC(C(=O)N2CCCCCC2)C1c1ccccc1F +CCN(CC(=O)C(C#N)c1nc(C(C)C)cs1)c1ccccc1 +COc1ccccc1NC(C)c1nc(-c2ccco2)no1 +CC1CCc2ccccc2N1C(=O)COc1cccc(-n2cnnn2)c1 +Nc1ccc(C2NCCc3c2ccc(F)c3Cl)cc1 +COCc1nc(C)c(C(=O)N2c3ccccc3SCC2C)s1 +C=CCOC(=O)c1cnc2nc(SCC#N)nn2c1C +CC1CCCCC1OCC(=O)N1CCCCC1CNS(C)(=O)=O +Cc1cc(C(N)C(=O)NCc2ccco2)ccc1O +O=C(OCC(=O)N1CCCCCC1)c1cnc2ccccn2c1=O +Cc1ccc(C)c(NC(=O)C2CC(O)CN2C(=O)OC(C)(C)C)c1 +CC(O)CCc1nc2ccc(NC(=O)c3cccnc3)cc2[nH]1 +COc1ccc(Cc2nc(C#N)c(N)o2)cc1OC +N#CCCN(Cc1cccnc1)Cc1cc(F)ccc1Br +O=C1CC2CCC(C1)N2CCCN1CCOCC1 +COc1ccccc1NC(=O)NCCC(O)c1cccs1 +CCC(C)C(NC(=O)c1ccn(-c2ccc(F)cc2)n1)C(=O)OC +Fc1ccc(C2CC(c3cccnc3)Nc3ncnn32)cc1 +CCCCC(=O)N1CC2CC(C1)c1cccc(=O)n1C2 +CS(=O)(=O)N1CCN(C(=O)CCOc2ccc(Cl)cc2)CC1 +Cn1cnnc1-c1ccccc1NC(=O)c1ccc(Cl)cc1F +CC(=O)NC(C(C)C)C1NCCc2c(O)cccc21 +CC(C)C(NC(N)=O)C(=O)Nc1cc(Cl)cc(Cl)c1 +Cc1cccc2c1nc(CCO)n2-c1ccc(N)nc1 +Cc1occc1CN(C)C(=O)c1csc(S(N)(=O)=O)c1 +CC(C)CNC(=O)CCC(=O)c1cccc(Br)c1 +CCCc1noc(CN(C)c2cc(C)ccc2C)n1 +CS(=O)(=O)N(C(=O)c1cccs1)c1cccc(O)c1 +COc1ccc(NC(=O)COC(=O)CC2CCCCC2)cc1 +Cc1cccc(-n2[nH]c(-c3ccccc3)cc2=O)c1 +Cc1ccc(-n2cc(-c3noc(-c4ccccc4)n3)nn2)cc1 +CC1CCCCN1C(=O)CSc1ccc(F)cc1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cc(-c2ccccc2)[nH]n1 +FC(F)(F)c1nc2nccc(-c3ccccc3)n2n1 +O=C(NCC(=O)N1CCCCC1)c1ccn(-c2ccccc2Cl)n1 +CC(=O)Nc1ccc(S(=O)(=O)n2cc(Cl)cn2)cc1 +COc1cc(O)ccc1C1NCCc2ccc(O)c(F)c21 +Cc1ccc2c(cnn2CCC(=O)NCCn2cccn2)c1 +COC(=O)c1ncc(OC)c2c1[nH]c1ccccc12 +CN(C)c1nc(N)nc(C(C#N)C(=O)Nc2ccccc2)n1 +CC(Oc1ccccc1C(F)(F)F)C(=O)N(C)C +COc1ccc(C)cc1NC(C)C(=O)Nc1ccc(NC(C)=O)cc1 +CC(CN1CCOCC1)NC(=O)NC(C)(C)c1ccc2c(c1)OCO2 +Cc1cnn(C2CCCN(C(=O)c3ccc4nc(C)c(C)nc4c3)C2)c1 +COCc1cc(OCc2ccc(C)cc2)nc(-c2ccncc2)n1 +O=C(CCNC(=O)c1ccco1)Oc1ccc(F)cc1 +CN(C)S(=O)(=O)c1c(Cl)cccc1Cl +COC(=O)C(CC(C)C)NC(=O)Nc1cccc(C)c1 +Oc1cnc(Cn2nnc3ccccc32)c2ccccc12 +CC1(C(=O)NCCc2ccccc2F)Sc2ccccc2NC1=O +CCCN(C)C(=O)c1cnn(C)c1-n1c(C)ccc1C +COc1ccc(-n2nc(Cn3cncn3)nc2C2(C)CCCO2)cc1 +O=C(c1ccc(-n2ccnc2)cc1)N1CCN(Cc2ccccn2)CC1 +O=C(NC1CC1)c1ccsc1NC(=O)c1ccnc2ccccc12 +O=C(CCCn1ccc2cc(Cl)ccc21)NCc1ccco1 +COCc1cccc(CNS(=O)(=O)c2ccccc2F)c1 +CC1CN(CCNC(=O)C2CCN(S(C)(=O)=O)CC2)CC(C)O1 +Cc1nccn1Cc1cccc(CNC(=O)c2n[nH]c(=O)[nH]2)c1 +COc1ccccc1NC(C)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +COC(=O)c1sccc1CN1CCN(c2ccccc2C#N)CC1 +Cc1ccc(C(=O)OCc2ccc3ncccc3c2)c(=O)[nH]1 +CCOC(=O)c1c(NC(=O)c2cc(C)on2)sc2c1CCCC2 +COc1ccnc(NC(=O)CC(C)C(=O)c2cccc(F)c2)c1 +CCOc1ccccc1C(=O)Nc1nc(-c2nonc2C)cs1 +C=CC1CCC(C(=O)OC)N1C(=O)OC(C)(C)C +CNC(=O)CNC(=O)c1ccc(Cl)cc1OC +Cc1cc(C(=O)N2CC3CCCC3(COCc3cccnc3)C2)no1 +Cc1cc(C)n(CC2CCCN2C(=O)c2scnc2C)n1 +CCc1nc(CC(=O)NC2COc3c(cccc3OC)C2)cs1 +C1=CC2N=CC=C2C(c2noc(Cc3cccnc3)n2)=C1 +CC1CN(CC(=O)N2CCC(C(=O)N3CCCC3)CC2)CC(C)O1 +Cc1nn(C)c(N)c1S(=O)(=O)NCc1ccccc1F +O=C(OCc1ccccn1)c1c2c(nc3ccccc13)CCC2 +CC(=O)Nc1ccc(C)c(NCc2nccn2CC(F)(F)F)c1 +CNC(=O)CN1CCN(S(=O)(=O)c2ccccc2)CC1 +COc1cccc(NC(=O)c2cc3c(nc2N)CCC3)c1 +O=C(CNC1CC1)OCc1ccccc1Br +COc1ccc(CCNC(=O)c2ccc3ccccc3n2)cc1OC +CC(NC(=O)c1ccccc1O)c1ccc(-n2ccnc2)cc1 +O=C(NCc1ccc2c(c1)CCC2)Nc1ccccn1 +Cc1nc(CCNC(=O)NCC(=O)N(C)C)cs1 +CC(C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)n1cccn1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1ccc(F)cc1Cl +Cc1cnc(C(=O)Nc2ccc(Oc3ccccc3)cc2)cn1 +COc1ccc(CC(=O)NCc2cnc(C)s2)cc1F +Cc1cc2cc(NC(=O)NCCNS(C)(=O)=O)ccc2o1 +COC(=O)CN1CCC(c2nc3ccccc3s2)CC1 +COc1ccc(C)cc1CC(O)Cc1cccnc1 +CCc1cc2c(=O)n(CC(=O)c3ccc(F)cc3)cnc2s1 +Cc1cc(C(N)=O)ccc1NCc1ccc(Br)cc1F +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1ccncc1 +CC(C)c1nc(C2CCN(C(=O)CCc3ccccc3)CC2)no1 +COC(=O)c1ccsc1NC(=O)c1cccc(C(F)(F)F)c1 +CC(=O)c1nc2cccc(F)c2n1-c1ncccc1C#N +CC(=O)Nc1cccc(C(=O)Nc2cc(Cl)ccc2F)c1 +CC(O)c1cccc(-c2ccnc3c2ccn3C)c1 +Cc1nsc(NC(=O)NC(C)c2ccncn2)n1 +CCC(C)(C)NC(=O)c1cccc(-n2cc(Br)cn2)c1 +O=C(c1cncc(-c2csc3ccccc23)n1)N1CCCCC1 +COc1ccc(NC(=O)Cn2ccc3sccc3c2=O)cc1 +Cc1onc(-c2ccccc2)c1C(=O)Nc1nnc(CC(C)C)s1 +CCOc1ccc2c(c1O)CCNC2C(O)c1ccccc1 +Cc1c(C)c2cc(Br)ccc2[nH]c1=O +O=C(Nc1ccc(F)c(Cl)c1)OCC1CCCO1 +CCN(Cc1ccoc1)S(=O)(=O)c1ccc(C#N)cc1Cl +Cn1cnnc1C1CCN(C(=O)NCCC(=O)NC2CCCC2)CC1 +COCc1nn2c(CO)c(-c3ccc(F)cc3)nc2s1 +COc1cc(OC)cc(C(NC(=O)OC(C)(C)C)c2nccn2C)c1 +CCc1nc(C)c(C(C)N(C)Cc2cc(OC)c3c(c2)OCO3)s1 +Cc1ncc(C(=O)NCCNC(=O)c2ccco2)s1 +CC(=O)c1c(C)[nH]c(C(=O)N(CCC#N)CCC#N)c1C +CCCCn1nc(C(=O)NCc2cccc(Cl)c2)ccc1=O +CC(C)NC(=O)Nc1cc(C(F)(F)F)ccc1F +Cc1nc(C)n(C2CCCN(C(=O)C3CCCc4ccccc43)C2)n1 +CN(C(=O)CC=Cc1ccc(F)cc1)c1ccccc1S(C)(=O)=O +O=S(=O)(NCCc1cccs1)c1cccnc1 +CCn1cc(NC(=O)Cn2cc(-c3nc(C)cc(NC)n3)cn2)nn1 +COc1ccc(Cc2n[nH]c(NC(=O)C3CC3)n2)cc1 +COCC1(NC(=O)c2ccc(=O)n(C)n2)CCCC1 +CCCCOc1ccc(C2Nc3ccccc3C(=O)N2C)cc1OC +COc1ccc(SCCC(=O)N2CCc3ccccc32)cc1OC +CCn1nc(C)c2c(C(=O)Nc3ccon3)cc(C)nc21 +CCOc1ccc(S(=O)(=O)NCC(C)N2CCOCC2)cc1 +COc1cc(C(=O)Nc2ccc(CN3CCCC3=O)cc2)ccc1C +Cc1ccc(OCc2cccc(C(=O)N(C)C3(C#N)CCC3)c2)cn1 +COC(=O)c1noc(C(=O)Nc2c(C)cc(C)cc2C)c1N +O=C(CSc1nc2ccc(C(F)(F)F)cc2[nH]1)N1CCC1 +CCC(C)NC(=O)c1nc(-c2ccc(N3CCCCC3)cc2)no1 +COc1ccccc1CNC(=O)CNc1cccc(C)c1C(N)=O +Cc1ccc(NC(=O)c2ccc(=O)n(C)n2)c(Cl)c1 +Cc1cnc(-c2cccc(NC(=O)NCc3ncc[nH]3)c2)o1 +CNC(=O)c1cc(NC(=O)C(C)Sc2ccccn2)ccc1F +CNc1ccc2ccnc(OCC3CCCO3)c2c1 +O=C(NCc1ccc(Cn2ccnc2)cc1)c1cc2ccccc2[nH]1 +Cc1nnnn1-c1cccc(NC(=O)C(C)OCC2CCCO2)c1 +CN(Cc1c(F)cccc1Cl)c1cncc(-n2cccn2)n1 +c1ccc(CN2CCCC2c2ccnc(Nc3nccs3)n2)nc1 +CC(C)OCC(=O)N(c1ccc(O)cc1)S(=O)(=O)c1ccccc1 +COc1ccc(-c2nonc2NC(=O)CC(C)C)cc1 +O=C(C1CC1)N1CCSc2nnc(COc3ccccc3)n21 +N#Cc1cc(Cl)ccc1NC(=O)c1ccccc1 +CC1CCN(C(=O)c2ccnc(OC3CCC3)c2)C(C)C1 +NC(=O)c1ccc(C(=O)Oc2ccc(NC(=O)C3CC3)cc2)cc1 +O=C(c1cc2c(s1)CCCC2)N1CCN(CCO)CC1 +COCC(=O)NC(C(=O)N(C)Cc1ccc(F)cc1)C(C)C +CCn1c(CC2CCN(C(=O)C(C)Cn3cccn3)CC2)n[nH]c1=O +CCN1CCN(C(=O)c2cnc3ncnn3c2C)CC1 +Cc1csc(C(C)N(C)C(=O)c2cc(-c3ccncc3)n[nH]2)n1 +O=C1NCC(=O)N2CC(Nc3nccc(CCC(F)(F)F)n3)CC12 +CC1CN(CC(=O)N2CC(C(N)=O)Oc3ccccc32)CCO1 +Cc1cnn(CCC(=O)N2CCCC2c2c(C)nn(C)c2C)c1 +Cc1noc(C2CCCN(C(=O)COc3ccc4c(c3)CCC4)C2)n1 +CC(=O)Nc1c2n(c3ccccc13)C(C)N=C1C2=Nc2ccccc21 +Cc1cc(C)cc(NC(=O)c2ccc(NC(N)=O)cc2)c1 +Cc1cccc(C)c1NC(=O)C(C)Sc1nnc2n1CCCCC2 +CN(C(=O)Cn1cnc2cc(-c3ccccc3)sc2c1=O)C1CC1 +CSc1ccsc1C(=O)NC(C)c1ccc2[nH]c(=O)[nH]c2c1 +CC(c1ccco1)N(C)C(=O)COc1ccc(Br)cc1 +C=CCN(C(=O)c1ccc(Cl)c(N)c1)C1CCCC1 +CC(C)NC(=O)c1ccc2c(c1)C(c1nc[nH]n1)CN2C +Cc1ccncc1NC(=O)NCC1CCN(c2ccccc2)C1 +CCCC(=O)NCCc1cc2c(C)ccc(C)c2[nH]c1=O +O=C(Cc1n[nH]c(=O)c2ccccc12)NCCOc1ccccc1F +NC(=O)CN(Cc1ccc(-c2ccccc2)cc1)C(=O)c1cccnc1 +Brc1ccc2c(c1)C(c1ccco1)NCC2 +Cn1ncc2c(N3CCCC(c4nc5ccccc5o4)C3)ncnc21 +CN(Cc1n[nH]c2c1CCCCC2)C(=O)C1COc2ccccc2C1 +O=S(=O)(c1c(F)cccc1F)N1CCC(O)CC1 +CSc1ccc(C2CC(O)=Nc3c2cnn3C(C)C)cc1 +O=C1C(NS(=O)(=O)c2ccccc2)CCCN1Cc1ccccc1 +Cc1ccc(Cl)c(OCc2cc(N)n(CCO)n2)c1 +Cc1cccc(NC(=O)Cc2csc(N3CCCC3=O)n2)c1C +C#CCCOC(=O)CCNC(=O)c1ccc(F)cc1 +Cc1cc2cc(CNc3ccccc3)c(=O)[nH]c2cc1Cl +COc1ccc(F)cc1C(=O)OCCN1CCCC1=O +COc1ccc(NC(=O)Cn2nc3n(c2=O)CCCCC3)cc1C +CC(C)(C#N)C(=O)N1CCc2cc(Br)ccc21 +CC(C)COC1CCN(C(=O)OC(C)(C)C)CC1 +CCOc1ncccc1C(=O)N1CCCC1c1ccc(F)cc1 +COc1ccc(OC)c(C(=O)CN(C)c2ccccc2)c1 +COCCNC(=O)NC(C)c1ccc(-c2ccccc2)cc1 +Cc1c(F)cccc1NC(=O)Cn1c(C2CC2)nc2ccccc21 +CN(CC(=O)OC1CCCC1)S(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(F)c(-c2nc(Cn3cccn3)c(C)o2)c1 +CCCN(C)C(=O)Nc1ccc(C)c(NC(C)=O)c1 +CC(=O)Nc1sc(C)c(C)c1C(=O)OCC(=O)N1CCOCC1 +CCc1cc(C#N)c(NC(=O)c2ccc(NC(=O)C(C)C)cc2)s1 +C=CCNC(=O)N1CC=C(c2ccc(F)cc2)CC1 +CC(C)c1nc(C2CCCCCN2C(=O)c2cccnc2)no1 +O=C(NCCc1ccc2c(c1)OCCO2)c1ccccc1O +CC(Nc1ncnc(N(C)C)c1N)c1ccccc1 +COc1ccc(OC)c2c1CN(c1ccc3nnnn3n1)CC2O +O=C(Nc1cnn(COc2ccc(F)cc2Cl)c1)c1cccnc1 +CCc1cc(C)c(C(=O)N2CCCC2CC(=O)c2cnn(C)c2)o1 +CNC(=O)c1ccc(Cn2ccc3ccccc3c2=O)cc1 +O=C(N1CCCCC1)N1CCc2nc(N3CCCC3)[nH]c(=O)c2C1 +Cc1cc(C(=O)N2CCN(CC(C)(C)CCC#N)CC2)on1 +COc1ccc(CNC(=O)c2cc(OC)c(OC)cc2C)cc1C +O=S(=O)(NC1CCCCCC1)c1ccc(O)cc1 +COC(=O)c1cc(C#N)c(Oc2ccccc2)nc1C +CCS(=O)(=O)NCCCNC(=O)c1ccc(Cl)c(Cl)c1 +CC(C)NC(=O)COC(=O)Cn1c(=O)[nH]c2ccccc21 +CCN(CC(C)C#N)C(=O)c1cnc2onc(C)c2c1 +CCc1nc(C)cn1S(=O)(=O)c1c(C)c(C)cc(C)c1C +Cc1csc(C(C)(C)NC(=O)c2ccnc(OC3CCC3)c2)n1 +CC(C)OC(=O)CCNC(=O)NC(C)c1ccccc1 +C#CCNc1ccc(NC(=O)OC(C)(C)C)c(OC)c1 +Cc1cc(F)ccc1N1CCCC(NC(=O)c2csnn2)C1 +C=CCn1c(C)nnc1SCC(=O)Nc1ccc(Cl)cc1C +O=C(NC1CCOc2c(Cl)cccc21)N1CCCC1 +Cc1cc(C(N)=O)ccc1NC(=O)Cc1ccc(Cl)cc1 +CCC(=O)c1ccc(OC(=O)Nc2ccccc2)cc1 +Cc1nc2ccccc2c(=O)n1-c1ccc(NC(=O)CC(C)C)cc1 +CCCCn1c(SCC(=O)N2CCCCC2)n[nH]c1=O +CCNc1nc(OC)nc(Oc2ccc(=O)n(C)n2)n1 +O=c1ccc(-c2nc(-c3cnccn3)no2)cn1Cc1ccccc1F +CCOC(=O)CN(C(=O)c1ccc(Cl)c(Cl)c1)C1CC1 +CCOC(=O)c1n[nH]cc1-c1cncn1CCn1nc(C)c(C)c1C +O=C(NCCc1nc(-c2ccncc2)n[nH]1)c1cc[nH]n1 +CCSc1cc(C(=O)Nc2cccc3c2C(=O)NC3)ccn1 +Cc1nn(C)c(C)c1C1CCCN1CC(O)c1ccc(F)cc1F +CCOc1ccc(CC(=O)Nc2ccnn2Cc2ccc(C)o2)cc1 +CC(=O)c1ccc(C(=O)NCCc2cccc(F)c2)s1 +CCCn1nc(-c2cc(Cl)ccc2OC)cc(N)c1=O +Cc1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)oc2ccccc12 +CCc1c(C(=O)N2CC(C)CC(C)C2)cnn1-c1ccc(OC)nn1 +C=CCn1c(SCC(N)=O)nnc1-c1ccc(N(C)C)cc1 +COc1cc2nc(C=Cc3ncc[nH]3)sc2cc1OC +CCn1nnnc1COc1ccc(C(=O)N2CCC(C)CC2)cc1 +N#CCCN(Cc1ccccn1)C(=O)COc1ccc(F)cc1F +C=CCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CCOC +CC(OC(=O)c1cscn1)c1ccc2c(c1)NC(=O)CO2 +Cc1cc(NC(=O)N2CCC(C)C2C)c2ncccc2c1 +CCCNC(=O)CCNC(=O)NC1CCN(c2ccccc2)CC1 +CCCOc1nc(C(C)(C)C)nc(NCC)c1N +CCOc1ncccc1CNC(=O)Nc1cccc(-n2cccn2)c1 +N#Cc1ccc(Cl)cc1N1CCCC(CCO)C1 +O=C(CC1CCCC1)N1CCC(c2nnc(-c3ccsc3)o2)CC1 +Nc1cc(=O)[nH]c(CCNc2cc(N3CCCCC3)ncn2)n1 +COc1ccccc1Cc1nnc2sc(SC)nn2c1=O +Cc1ccc(-n2ncc3c(=O)n(NC(=O)C4CC4)cnc32)cc1C +O=C(CNc1cccc(F)c1)NCCc1ccccc1 +CCN(CC)C(=O)C1CCN(C(=O)c2ccccc2Cl)CC1 +CC(=O)Nc1ccc(O)c(C(=O)Nc2cccc(F)c2)c1 +O=C(c1cn(-c2ccccc2)nn1)N1CCOCC1 +CC(=O)NC(C(=O)NC(C)c1ccncc1)C(C)C +CN(CC(N)=O)C(=O)Cn1ccc(=O)c2ccccc21 +CCn1nc(-c2cc(Cl)ccc2OC)cc(C#N)c1=O +N#Cc1ccc(S(=O)(=O)NCc2ccc(N)cc2Cl)cc1 +CCC(NC(=O)N1CCCN(C(=O)C2CC2)CC1)c1c(C)noc1C +COc1ccc(OC2CCN(C(=O)c3ccc(C#N)cc3)CC2)cc1 +COc1ccccc1-c1nnc(SCc2c(C)noc2C)o1 +CC(C)Cc1noc(C2CCCCN2C(=O)c2ccco2)n1 +CC(C)(C)c1nc(CNC(=O)C2CCOc3ccccc32)cs1 +CS(=O)(=O)NC1CCCN(C(=O)Nc2cccc(Cl)c2F)C1 +COc1ccccc1C1CC(=O)Nc2c1c(=O)n(C)c(=O)n2C +OC(COc1ccc(Cl)c2cccnc12)CN1CCOCC1 +O=C(NCCSc1ccccc1)c1cccnc1N1CCCC1 +CC(=O)Nc1nc2cc(C)c(Br)cc2s1 +CCc1cccc(NC(=O)CS(=O)(=O)c2ccc(F)cc2)c1 +Cc1cc(C(=O)N2CCC(C)CC2)ccc1NC(=O)N(C)CC(C)C +Cc1cc(NC(=O)Cc2cccc(N)c2)ccc1Br +Cc1cn2nc(NC(CN3CCOCC3)c3ccccc3)sc2n1 +Cc1n[nH]c(C)c1NC(=O)CNC(C)c1ccccc1-n1cccn1 +COc1ccc(-n2nc(C)c3c2CC(C)(C)CC3=O)cc1 +CCC(Sc1nc(N)cc(N)n1)C(=O)Nc1cc(C)on1 +CCC(C)NC(=O)NCc1cccc(COC)c1 +COc1ccc(NC(C)=O)cc1NC(=O)c1sc(C)nc1C +CC(CNC(=O)c1ccc2[nH]ccc2c1)Oc1ccccc1 +O=C(NCCc1ccccn1)N(Cc1cccc(F)c1)C1CC1 +O=C(Nc1ccc(F)cc1OCC1CC1)N1CCN(CCO)CC1 +COC(C(=O)OC(C)C(=O)N(C)C)c1ccccc1 +CC1CCC(NC(=O)C2CCCN(C(=O)C(C)C)C2)CC1 +N#Cc1ccc(C(=O)Nc2cccc(Cl)c2)c(F)c1 +Cc1cc(N)ccc1S(=O)(=O)N1C(C)CCCC1C +CCN(CC)c1ccc(NC(=O)C2CCOC2)cn1 +Cc1ccc(NC(=O)CN(C)C(=O)Cc2c[nH]c3ccccc23)cc1 +Cc1cc(CN2CC3OCC(C(=O)Nc4cccnc4)C3C2)no1 +O=C(Nc1ccc2c(c1)OCCO2)c1ccccc1OC(F)F +CCOC(=O)c1ccc(NC(=O)CSc2cc[nH]c(=O)n2)cc1 +COc1ccc(F)cc1C(=O)COC(=O)c1ccc(O)cc1O +Cc1ccc(-c2ncc(C(=O)N3CCCC3)c(N)n2)cc1 +Cc1cc(S(=O)(=O)NCC(C)(C)O)ccc1Cl +Cc1nc(C)n(C2CCCN(C(=O)CCOc3ccccc3)C2)n1 +CCN(CC(=O)Nc1cccc(CN(C)C(C)=O)c1)c1ccccc1 +Cc1ccc2nc(C(=O)NCc3cccc(Cl)c3)cn2c1 +CN1C(=O)C2(OCC(COc3ccc(Cl)cc3)O2)c2ccccc21 +CCC(C)N(C)C(=O)C(NC(=O)c1ccccc1)C(C)C +COC(=O)NCC(=O)N1CC(=O)N(c2ccc(OC)cc2)CC1C +Cc1cc(C(=O)NC2CCCc3[nH]c(=O)ccc32)on1 +COc1ccccc1NCCC(=O)c1cc(F)ccc1F +COC(=O)C1=C(C)C(C(=O)C(C)N2CCCCCC2)=NC1C +CCc1nnc2n1CCN(C(=O)CCn1nc(C)cc1C)C2 +CCOC(=O)c1sc(NC(=O)CCc2cn(C)nc2C)cc1C +CC(C)C(=O)Nc1cccc(NC(=O)CCc2cccc(N)c2)c1 +CCOC(=O)C1(NC(=O)c2cccc(OC)c2F)CCCC1 +O=C(CCNC(=O)c1ccncc1)Nc1ccncc1 +CCc1noc(C2CCCCN2S(=O)(=O)c2ccccc2)n1 +O=C(CCc1ccsc1)NCc1ccc(CN2CCCC2=O)cc1 +COc1cccc(CC(=O)N2CCOC3C(OC)CCC32)c1 +CCc1ccccc1NC(=O)CS(=O)(=O)c1ccccc1F +Fc1ccc(F)c(-c2csc(N3CCOCC3)n2)c1 +Cc1ccc(C)c(OCC(=O)NC2CCCc3ccccc32)c1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(OC)cc2F)cc1 +CCS(=O)(=O)c1ccc(NC(=O)C2(C#N)CCCC2)cc1 +CCn1nc(C)c(Nc2ncnc3c(C)n(C)nc23)c1C +CC(C)(NC(=O)Nc1cc(-n2cnnn2)ccc1F)c1nccs1 +CCOC(=O)c1[nH]c(C)c(C(=O)Nc2ccc(F)cc2C)c1C +CC#CCN(c1ccc(C(C)=O)cc1)S(=O)(=O)CC +CC(C)(C)C(C#N)NC(=O)CNC(=O)C1CCCC1 +CCCOC(=O)c1nnn(-c2ccccc2F)c1C +O=C(NCCC1CCCO1)c1cc(C2CC2)nc2ccccc12 +O=C(c1cccc(NCc2nnc(C3CCC3)o2)c1)N1CCOCC1 +O=C(CSc1nnc2ccccn12)NCCc1cccs1 +Cc1cc(C)cc(OCCNC(=O)CCC(=O)N2CCOCC2)c1 +CN(C)C(=O)C1CCCN1C(=O)CCCNC(=O)C(C)(C)C +CC1CCN(C(=O)C(C#N)Cc2ccc(F)cc2)CC1 +O=C(C1CCOC1)N1CCOc2c(Cl)cccc21 +Cc1ccccc1COC(=O)c1n[nH]c(=O)c2ccccc12 +CC(NC(=O)Cc1ccc(F)cc1)c1ccc(-n2cncn2)cc1 +Cc1cccc(C(=O)NC2(C)Cc3ccccc3C2)n1 +Cc1nc(Nc2ccc(O)cc2)c2cc(C)sc2n1 +O=C(c1ccc(CN2CCOCC2)cc1)N1CCCC1 +O=C(Cn1cnc2ccccc2c1=O)Nc1cc(F)ccc1F +NS(=O)(=O)c1ccc(C(=O)NCCOc2ccc(F)cc2)cc1 +N#CCS(=O)(=O)NCc1ccc(-c2ccc3c(c2)CCCO3)cc1 +O=C(c1cnc(C2CC2)nc1)N1CCC(Cc2ccc(F)cc2)CC1 +CCn1c(CCNC(=O)c2cccc(F)c2)nc2cccnc21 +CCN(CC)C(=O)CCC(=O)N1CCOc2ccc(F)cc21 +Cc1nc(C)n(CC2CCCN2c2nccc(C(F)(F)F)n2)n1 +CCCc1cc(C(=O)Nc2nc(CN3CCOCC3)cs2)[nH]n1 +CCN1CCc2nc3ccccc3c(CC#N)c2C1 +CNC(=O)CN1CCN(C(=O)c2ccc3c(c2)ncn3C(C)C)CC1 +O=C(Nc1ccc(Br)cn1)c1cc2ccccc2[nH]1 +O=C(NC(C1CC1)C1CC1)c1cc2ccccc2[nH]c1=O +COC(=O)C1(N(C)C(=O)c2cc(C)n(C3CC3)c2C)CCCCC1 +CC(C)C(NC(=O)NCc1ccccc1)C(=O)NCC(N)=O +CCCC(C)C(=O)NC(CC)c1ccc(OC)cc1 +CCOCCCNC(=O)Cc1ccc(Cl)c(Cl)c1 +Cc1noc(COC(=O)CCc2ncc(-c3ccccc3Cl)o2)n1 +Cc1noc(C2CCCN(C(=O)CCc3ccncc3)C2)n1 +Cc1nn(C)c(C)c1S(=O)(=O)N(CCCO)C(C)C +CN(Cc1cnn(-c2ccccc2)c1)C(=O)c1ccc2ccccc2c1 +Cc1ccccc1NC(=O)c1c(-c2ccccn2)cnnc1N +Cc1cc(NC(=O)NCC(C)C(=O)OC(C)C)no1 +CCC(CC)CNC(=O)NCc1ccc2c(c1)OCO2 +COc1ccccc1C(=O)NCc1cc(C)nc(N2CCOCC2)n1 +O=C(Cc1cccs1)N1CCC(Oc2cccnn2)CC1 +CCN(Cc1ccco1)C(=O)Nc1ccc(F)c(Cl)c1 +CC1CCc2c(sc3nc(C(C)N(C)CCC#N)[nH]c(=O)c23)C1 +CC(=O)NCCNC(=O)NCCc1ccccc1Cl +Cc1nc(C2CC3CN(C(=O)c4cscn4)CC3O2)no1 +CNS(=O)(=O)c1ccc(C(=O)NCc2ccccc2CO)cc1 +O=C(NCC(=O)N1CCN(c2ccccc2F)CC1)C1CCCCC1 +COCC(=O)NCCn1ncc(-c2cc(C)no2)c1-c1cccs1 +O=S(=O)(c1ccc(F)cc1)N1CCCCC1c1cccnc1 +COc1ccc(S(=O)(=O)N(C)CC(=O)NC2CCCC2)cc1 +CCNc1nnc(-c2c(CC)oc3c2CCC3)s1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1ccoc1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)Cc1ccc[nH]1 +CCOc1ccccc1NC(=O)c1nccc2c(N)cccc12 +C=CCn1ccc2ccn(CCCN3CCOCC3)c(=O)c21 +CC1CCCN(C(=O)CSc2ccccc2Cl)C1 +COc1c(C)cnc(CNC(=O)NCCOc2cccc(F)c2)c1C +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)Nc1cc(C)on1)O2 +c1ccc2oc(-c3noc(CCc4nc(C5CC5)no4)n3)cc2c1 +CC(=O)c1ccccc1C(=O)N1CCCC2(CN(C)C(=O)O2)C1 +O=C(NCc1ccccc1F)c1cccc2c1NCCC2 +CN(Cc1ccco1)C(=O)Nc1ccc(OC(F)F)c(F)c1 +CC1CCCN(C(=O)c2ccn(C3CCCC3)n2)C1 +CCC(=O)N1CCCC1C1CCCN1c1nn2cc(C)nc2s1 +O=C(Nc1cccc2ccccc12)NC(CCCO)c1ccccc1 +CCC(=O)Nc1ccc(S(=O)(=O)CC2CCCO2)cc1 +COc1ccc(OC)c(C(=O)Nc2cccc(S(C)(=O)=O)c2)c1 +CCOc1ccc2nc(SCC(=O)NC(C)(C#N)C(C)C)[nH]c2c1 +CC(C)(C)Oc1cc(CNC(=O)c2cc[nH]c2)ccn1 +CC(NC(=O)CS(=O)(=O)c1nncn1C(C)C)c1ccccc1 +CCOC(=O)CN(C(=O)Cc1ccc(C)cc1)C1CC1 +O=C(Nc1ccccc1)NC1CC(=O)N(Cc2ccccc2)C1 +CCc1ncncc1C(=O)NCCNC(=O)c1ccc(F)cc1F +CCC(C)c1ccc(C(=O)C2CCN(C(C)=O)CC2)cc1 +CC(=O)c1ccc2c(c1)CCN2Cc1cccc(OCCO)c1 +Cc1cc(C)cc(N(CCC#N)C(=O)CSc2nnnn2C)c1 +O=C(NCc1nncn1C1CC1)Nc1ccc(OC(F)(F)F)cc1 +C=CCOC(=O)N1CCC(=O)CC1Cc1ccccc1 +CC(=O)NC(C(=O)NCc1ccc(N2CCCCC2=O)cc1)C(C)C +Cc1nccn1-c1ccc(NC(=O)c2cccc3ncccc23)cn1 +O=S(=O)(c1ccc(Cl)c(Cl)c1)N1CCOCC1CCO +O=C(Nc1cc(Cl)ccc1Cl)c1ccc(N2CCCC2=O)cc1 +O=C1C2CCCN2c2ncccc2N1Cc1c(F)cccc1Cl +Cc1nn(C)cc1CNC1(c2ccc(F)cc2F)CCOCC1 +Cc1nnc(SCC(=O)NCCc2cccc3cccnc23)s1 +CCOc1ccc(NC(=O)C2CCN(C(C)=O)CC2)c(C)c1 +COC(=O)CCN(Cc1nc2c(F)cccc2[nH]1)C(C)C +Cc1ccc(-c2noc(CCC(=O)N3CC(C)OCC3C)n2)cc1 +O=C(c1cnccn1)N1CCCC2(CC(Nc3ncccn3)CO2)C1 +CCOC(=O)Nc1ccc(NCc2cc3ccccc3[nH]c2=O)cc1 +CC1(C)C(=O)Nc2c(Cl)cc(C(O)C3CCCO3)cc21 +O=C(COc1ccc(CO)cc1Br)N1CCCC1 +CCOc1cc(CO)cc2c1OC(CC)(CC)C(=O)N2CC +COC(=O)C(CNC(=O)c1ccccn1)Oc1ccc(F)cc1 +Cc1cccc(C2CC(=O)Oc3c2c(=O)[nH]c2ccccc32)c1 +Cc1ccc(N(CCC#N)C(=O)Cn2cnc(C#N)n2)cc1 +O=C(CSc1nc(-c2ccccn2)n[nH]1)NC1CC2CCC1C2 +CCOC1COCC1NC(=O)c1cnn2ccn(C)c12 +COC(=O)c1sccc1NC(=O)COc1ccccc1F +CCCC(=O)N1CCCC1C(=O)N1CC(c2ccccc2C)CC1C +COc1cccc(NC(=O)c2cccc(OC)c2Cl)c1 +O=C(NCC1CCCO1)c1ccc(COc2ccc3c(c2)CCC3)o1 +COc1cccc(C2CC2C(=O)Nc2ccc3c(c2)COC3)c1 +CC1CCN(C(=O)COc2ccc3ccc(=O)oc3c2)CC1 +Cc1ccc(CC2COCCN(C(=O)C3CCC3)C2)nc1 +Cc1ccc(CNC(=O)NCc2cnn(C)c2)cc1 +CC(C)(C)OC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CCOc1ccc(C(=O)Nc2n[nH]c(-c3ccccc3OC)n2)cn1 +N#Cc1cccnc1NCCNC(=O)c1ccc2ccccc2n1 +CCNC(=O)CN(C)C(=O)c1cccc2[nH]ncc12 +CCC(=O)c1ccc2c(c1)N(CC(N)=O)C(=O)C(C)(C)O2 +CCCOc1cc(NC(C)c2ccc(OC)cc2)ncn1 +Cc1cccc2nc(C(=O)N3CCCC3C(=O)Nc3ccccc3)cn12 +CCOC(=O)CN(C(=O)c1ccc(C(C)C)cc1)C(C)C +Cc1noc(C2CCCN(C(=O)c3ccc(Cl)cc3F)C2)n1 +CCn1cc(NCc2cc(Br)cs2)ccc1=O +CS(=O)(=O)NC1CCN(CC#Cc2ccc(F)cc2)C1 +O=C(Cn1c(=O)cnc2cccnc21)NC1CCCCC1 +N#Cc1cccc(C(=O)Nc2cnc(N3CCCCC3)nc2)c1 +O=C(NCc1ccccn1)NC1CCc2cc(Cl)ccc21 +NC(=O)c1cccnc1N1CCN(c2ncccn2)CC1 +Cc1cc(N)c(C(=O)c2ccccc2Br)o1 +CC(=O)NCCOc1nc(N(C)C)nc(N2CCOCC2)n1 +O=C(CCC(=O)N1CCOCC1)OCCc1cccs1 +CCC1CCC(NC(=O)c2cc(S(N)(=O)=O)ccc2Cl)CC1 +Brc1ccccc1CNCCc1ccccn1 +COCc1cc(OCc2ccc(C)cc2)nc(N2CCOCC2)n1 +CCc1onc(C)c1NC(=O)C(C)Cc1ccccc1 +Cc1csc2ncc(C(=O)Nc3cccnc3)c(=O)n12 +COc1ccc(NC(=O)CN2CCN(c3ccc(F)cc3)C2=O)cn1 +CCOCCC(=O)Nc1ccccc1C(=O)N1CCOCC1 +N#CCCn1nc(-c2cccs2)c2c1CCNC2 +CN(C(=O)CCSc1ccc2c(c1)OCCO2)c1ccccc1F +Cc1nn(C)c2nc(-c3ccn(C)n3)cc(C(F)F)c12 +CC(C)NC(=O)Cc1cccn1-c1cccc(Cl)c1 +Cc1cc(C#N)c(NCc2ccc(F)cc2C)s1 +COC(=O)CNC(=O)c1sc2ncccc2c1-n1cccc1 +CCCc1[nH]nc(C(=O)Nc2cccc(C)n2)c1N +O=C(NCC(=O)N1CCOCC1C1CC1)c1cc2ccccc2[nH]1 +CCCCCNC(=O)c1cccc(-n2cnnn2)c1 +Cc1ncsc1CNC(=O)NC1CCN(c2ncccn2)CC1 +COC(=O)c1c(C)[nH]c(C(=O)NC(C)Cc2cccc(Cl)c2)c1C +COc1cc(C)ccc1NC(=O)C1CC(=O)N(Cc2ccccn2)C1 +COc1ccc(-c2c(CN3CCOCC3)noc2N)cc1 +CCN(CC)c1cc(N2CCCC(CO)C2)ncn1 +Cn1c(Cc2ccccc2)nnc1SCC(=O)NCc1ccco1 +CCCN(CCC)C(=O)Nc1cccc(-c2nnnn2C)c1 +O=C(CCNC(=O)c1ccccc1Cl)NCc1ccccc1 +COc1c(C(=O)Nc2ccc3nc(C)oc3c2)c(C)nn1C +CC(C)(C)N1CC(C(=O)Nc2ccccc2Br)CC1=O +Cc1nc2ccccc2c(=O)n1NCc1ccc(OC(F)F)cc1 +CCc1cccc(NC(=O)Cc2csc(CC)n2)c1 +CCCCC(=O)NC1CCN(C(=O)c2cccc(C#N)c2)CC1 +C=CCN(Cc1ccc(OC)c(OC)c1)C(=O)N1CCOCC1 +Cc1ccc(OCC(=O)N(C)c2ccc(S(C)(=O)=O)cc2)cc1C +Cc1ccc(C(O)CNC(=O)c2cc(Cl)ccc2Cl)o1 +COc1ncnc2c1CCN(C(=O)c1ccc3c(c1)OCO3)C2 +COC(=O)CCN(C)C(=O)CSc1ccccc1 +Cc1cc(C(=O)NCC(O)c2cccc(OC(C)C)c2)c(C)o1 +CS(=O)c1ccc(CNc2ccn(-c3ncccc3Cl)n2)cc1 +CCN(C(=O)CNC(=O)NC)C(C)Cc1ccc(OC)cc1 +COCC(NC(=O)c1cc(-c2ccccc2)cc(Cl)c1O)C(N)=O +CCc1ccc(OCCc2nnc(NC(C)=O)s2)cc1 +Cc1csc(C2CCCN(C(=O)c3c[nH]c(C(C)C)n3)C2)n1 +COc1cccc2ccc(N3CCN(C)C(=O)C3)nc12 +CC(NC(=O)c1cccc(C#N)c1)c1cccc(N2CCCC2)c1 +CN1CCN(C(=O)c2nccc3c(N)cc(F)cc23)CC1 +CCNC(=O)c1ccc(N2CCC(n3ccnn3)CC2)nn1 +CC(C)(C)Oc1cc(CNC(=O)Cc2ccc(F)cc2)ccn1 +O=C(NCc1cscn1)c1cn(-c2ccccc2)nn1 +Cc1ccc(C(=O)N2CCN(c3ccc(-n4cccn4)nn3)CC2)cc1 +CC1(C)COc2c(Cl)ccc(Cl)c2NC1=O +CN(C(=O)c1cc2ccccc2[nH]1)C1(C#N)CCC1 +Cc1nscc1C(=O)N(C)Cc1ccc(Cl)cc1 +NC(=O)c1csc(CN2CCCC2COc2ccccc2)c1 +Cc1ccc(N)c(NC(=O)c2ccc(Br)cn2)c1C +CCOC(=O)c1nc(-c2ccccc2)ccc1C#N +Fc1cnc(N2CCC3CN(c4ncccn4)CCOC3C2)nc1 +CC(NC(=O)Nc1ccc2oc(=O)n(C)c2c1)c1ccccc1Cl +COc1nc(C2CCCCC2)nc(NC2CC2)c1N +Cc1ccc2nnc(C(=O)NCCCN3CCOCC3)nc2c1 +O=C(OCCc1cccs1)C1CCCN(C(=O)C2CC2)C1 +CCOC(=O)c1csc(NC(=O)c2cn3cccnc3n2)n1 +Cc1noc(CN(C)C2c3cc(Cl)cc(Cl)c3CC2O)n1 +O=C(CNC(=O)c1cccc(Cl)c1)NCc1ccccc1F +Cc1c(C(=O)NC2CCN(c3ccccc3)CC2)cnn1C +CCc1ccc(N2CC(C(=O)NCc3cccc(F)c3)CC2=O)cc1 +CNC(CC(=O)OC)C(=O)c1ccc(N(C)C)cc1 +COC(=O)COc1ccc(NC(=O)Cc2ccccc2Cl)cc1 +Cc1nnc(SCC(=O)N2CCC(C)CC2)n(N)c1=O +CC(C)CC(=O)Nc1ncnc2c1C(=O)CC(C)(C)C2 +O=C(CCc1cc(F)ccc1F)NCCc1cccnc1 +CC(C)C(C)NC(=O)CN(C)c1ccc(F)cc1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)NCc3ccc(F)cc3)c12 +O=C(OCC1CC(=O)N(C2CC2)C1)c1cccc(Cl)c1Cl +O=C(Nc1ccc(OC(F)(F)F)cc1)NC(CO)c1ccccc1 +CCc1nnsc1C(=O)Nc1nc2ccc(C)cc2s1 +Cc1ncn(Cc2nc(-c3ccccc3Cl)oc2C)n1 +Cc1ccc(C(=O)NCCNC(=O)c2ccccc2F)cc1F +CCOC(=O)c1c(C)[nH]c(C(=O)NC(C)CO)c1C +Cn1nc(C2CCCN(Cc3ccccc3)C2)c2nccnc21 +CC(C)CC(NC(N)=O)C(=O)NCc1ccc(Cl)cc1 +COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1cccc(C)c1 +CCNC(=O)CNC(=O)c1ccc(OCC2CCCCC2)cc1 +O=C(CSc1nncs1)N1CCOC2CCCCC21 +CC(=O)Nc1ccc2c(c1)CN(C(=O)CC(C)C)C(C(=O)N(C)C)C2 +O=C(CCCc1c[nH]c2ccccc12)OCC1CCCCO1 +COc1cc(OC)cc(C(NC(=O)C2=NC=CC2)c2nccn2C)c1 +CN1CC(NC(=O)Cc2cccc(O)c2)CCC1=O +CCn1ncc2c(C(=O)NCCOC)cc(-c3cccs3)nc21 +CN(C)C(=O)Cn1nc(-c2cccs2)cc(N)c1=O +O=C(Nc1ccc(-n2nccn2)cc1)C1Cc2cc(Cl)ccc2O1 +CCn1ccc(C(=O)N2CCC(c3cc(-c4ccccc4)n[nH]3)CC2)n1 +COCCNC(=O)NCc1cccc(Cn2ccnc2)c1 +O=C1CCN(C(=O)Cc2ccc(F)cc2F)CCN1 +CC(C)C(=O)Nc1ccc(CSc2ncn[nH]2)cc1 +Cc1cc(C)n(CC(C)CNC(=O)C2CCCC2)n1 +Cc1cc(C)n(-c2ccc(F)cc2-c2ncc[nH]2)n1 +CC(C)NC(=O)Nc1ccccc1C(=O)OCC1CCCO1 +COCCCNc1ccc(-c2nc(-c3ccccc3)no2)cn1 +N#CCCCCS(=O)(=O)c1ccc2c(c1)OCCO2 +CC1CN(c2ccccc2NC(=O)NCc2ccccc2)CC(C)O1 +COCC(=O)Nc1cc2ccccc2cc1C(=O)OC +COc1ccc(S(=O)(=O)N(C)c2ccc(C(N)=O)cc2C)cc1 +Cc1ccc2ncc(C(=O)NCCC3=CCCC3)n2c1 +CC(CC#N)N(C)Cc1cccc(NC(=O)OC(C)(C)C)c1 +CC(C)NC(=O)CN1CCN(C(C)C(N)=O)CC1 +Cc1ccc(Cl)cc1S(=O)(=O)N1CC2(COC(C)(C)OC2)C1 +CC(C)C(=O)N1CCC(=O)N(Cc2ccccc2Cl)CC1 +NC(=O)c1ccc(NC(=O)c2ccccc2OC2CCC2)cc1 +CC(C)C(=O)N1CCCN(C(=O)c2ccccc2Cl)CC1 +CCOC(=O)CN(C(=O)c1cnns1)C1CC1 +COc1ccccc1-c1nnc(SCC(N)=O)n1N +O=C(NCCSc1ccccc1)c1ccnc(-n2cnnc2)c1 +CCc1cccc(C)c1NC(=O)COC(=O)c1ccc(Cl)c(N)c1 +O=C(Cc1cn2ccsc2n1)Nc1ccccc1OCC1CC1 +CCOC(=O)c1ccsc1NC(=O)COc1ccc(C#N)cc1 +CCNC(=O)c1ccc(CN2CCOCC2)c(N)c1 +CC(C)(C)N1CC(C(=O)NCCN2CCOCC2)CC1=O +CCCCN1CC2(CCCN(C(=O)COCC)C2)CCC1=O +Cc1ccc(NC(=O)c2ccc(COc3ccccc3C#N)o2)nc1 +Cc1ncc(C(=O)NCCSc2nnc(C)s2)c(=O)[nH]1 +Cn1c(N)c(Sc2nc3ccccc3s2)c(=O)[nH]c1=O +Cc1cccc(CN(Cc2ccccn2)C(=O)Cn2cnnn2)c1 +COCCOCCNC(=O)c1cc(C)ccc1O +Cc1cc(C)nc(NC(=O)c2ccc(OC(C)C)cc2)n1 +O=C(Nc1nncs1)NC1CCN(C(=O)c2ccco2)CC1 +O=C(Cn1c(-c2cnccn2)noc1=O)Nc1ccccc1 +OCCOc1cccc(-c2nccn2-c2ccc(-n3cccn3)cc2)c1 +Cc1nn(CC(=O)c2ccc(C(C)(C)C)cc2)c(=O)c(C#N)c1C +Cn1c(=O)n(C)c2cc(S(=O)(=O)N3CCCC3C(N)=O)ccc21 +COc1cn2c(cc1=O)C(=O)N(CCNC(=O)c1cnccn1)CC2 +CNC(=O)CN(C)S(=O)(=O)c1ccc(C)cc1Cl +Cc1cc(OCCC2OCCO2)cc(C)c1Cl +Fc1cc(F)c2c(c1)CCNC2c1ncccc1Cl +Nc1cccc2c1nc(-c1cccc(F)c1)n2CCO +CSc1ccc(OC(=O)Cc2ccc(NC(C)=O)cc2)cc1 +CCOC(=O)CCC(C)NC(=O)N1CCC(c2cnn(C)c2)CC1 +O=C(NC1CCN(C(=O)C2CCCCC2)CC1)c1ccc[nH]c1=O +COc1ccc(-c2ccc3ncccc3c2)nc1N +CCc1onc(C)c1NC(=O)CC1CCCCC1 +CNC(=O)NC(C)(C)C(=O)NCC(C)c1ccccc1 +O=C(Nc1ccc(-c2nccs2)cc1)c1ccncc1F +O=C(NC1CCc2ccccc21)c1cc(-c2ccc(F)cc2)[nH]n1 +O=C(C1CC1c1ccc(Cl)c(Cl)c1)N1CCCn2ncnc21 +CCC(C)(C)NC(=O)c1cc(C)n(Cc2ccccn2)c1C +COc1c(CNC(=O)Nc2ccn(-c3ccccc3)n2)c(C)nn1C +CCCc1noc(CSc2ccccc2O)n1 +COc1c(F)cc(NC(=O)N(C2CC2)C(C)C2CC2)cc1F +Cc1cc(NC(=O)c2ccc(-n3cncn3)nn2)on1 +CC(=O)c1c(C)[nH]c(C(=O)N2CCCC(NS(C)(=O)=O)C2)c1C +CCOc1cc(C#N)ccc1OC(=O)C1CC1c1ccc(F)cc1 +Cc1nc(S(=O)(=O)NCc2ccc(Cl)cc2)cn1C +Cc1cc(C(F)(F)F)nc(CCNC(=O)c2ccc(Cl)cn2)n1 +CC(Oc1cccc(C#N)c1)C(=O)N1CCN(Cc2ccccc2)CC1 +Cc1ccc2c(C)nc(Nc3nc(C)cc(=O)[nH]3)nc2c1 +NC(=O)N1CCCC(C(=O)NCCc2ccc(F)cc2)C1 +C#CCCN1CCN(S(=O)(=O)c2ccc(C)s2)CC1 +COC(=O)C1CCCCN1C(=O)Cc1c[nH]c2ccccc12 +Cc1nc(-c2ccccc2O)n(Cc2ccccc2)n1 +N#Cc1ccccc1NC(=O)CCC(=O)c1ccc(N)cc1 +CC(=O)Nc1ccc(C(=O)OCc2cc(-c3cccs3)on2)cc1 +O=C(CS(=O)c1ccc(F)cc1)Nc1ccccc1Cl +Cc1cnc2c(c1)nc(C1CC1)n2CCOc1ccc(N)c(C)c1 +O=C(Nc1ccc(C(=O)N2CCCCCC2)cc1)c1ccncc1F +Cc1cc(C)nc(NCCC(=O)NCCc2nnc3ccccn23)n1 +C=CCNC(=O)N(C)Cc1nccn1CC(F)(F)F +N#CC(CCC(=O)NCc1ccncc1)c1ccco1 +CC(C)c1cc(=O)[nH]c2cc(NC(=O)c3ccc(C#N)cc3)ccc12 +CCn1nnc2ccc(-c3noc(-c4cnccn4)n3)cc21 +COCCNC(=O)Cc1nc(-c2cccs2)oc1C +CN(C)C(=O)C1CCN(C(=O)C2(c3cccc(F)c3)CCCC2)CC1 +COC(=O)Cn1c(C#N)nc2cc(C(=O)OC)ccc21 +O=C(Cc1ccc2c(c1)CCO2)N1CCN(c2ncccn2)CC1 +O=C(NC1CN(c2nncs2)CC2CCCOC21)c1cccnc1 +CNC(=O)CN1CCN(C(=O)c2cc(Br)c[nH]2)CC1 +O=C(Nc1ccc(F)cc1)c1sccc1Cl +N#Cc1cccc(CN2CCOCC(Oc3ccccc3)C2)c1 +COc1ccc(CC2CN(C(=O)c3cnn(C(C)C)c3)CCO2)cc1 +CC1CCCC(N(C)C(=O)CCCc2nc3ccccc3c(=O)[nH]2)C1 +CCc1ccc(NC(=O)c2onc(S(C)(=O)=O)c2N)cc1 +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)C1CCCCC1 +CNC(=O)C1CCCN1C(=O)Nc1ccc2nc(C(C)C)sc2c1 +O=C(NC1CCCCC1O)c1ccc2[nH]cnc2c1 +Cc1cc(NC(C)c2n[nH]c(=O)[nH]2)n2nccc2n1 +Cn1cc(C(=O)NCc2nnc3ccccn23)c2ccccc2c1=O +O=C(CC1C=CCC1)NCC(=O)OCc1ccccc1 +O=C(Cn1cnc2sccc2c1=O)NCc1ccc(F)cc1 +Cc1cc(NC(=O)N2CCCC(CO)C2)ccc1Oc1cccnc1 +Cc1cc(C)c(S(=O)(=O)N(C)C(=O)C2CCC(C)O2)c(C)c1 +c1cc2c(c(C3CCCN3c3ncnc4[nH]cnc34)c1)OCCO2 +CC(=O)c1c(-c2ccc(F)cc2)cnn(CCC(C)C)c1=O +OCc1ccccc1NCc1cccc(OCc2ccccn2)c1 +CC(=O)c1c(F)cccc1Sc1nnnn1C +CNC(=O)NCC(=O)N1CCc2ccccc2CC1 +Cn1nncc1CNc1cnn(-c2ccccc2)c1 +CC(Oc1ccccc1)C(=O)NCc1ccc(-n2ccnc2)cc1 +CN(CC(=O)NCC1(C(N)=O)CCOCC1)c1ncnc2[nH]cnc12 +COc1ccc(CC(=O)NCCCn2cccn2)cc1 +CC(C)(C)c1cnc(Cn2cnc(C#N)c2C#N)o1 +O=C(c1cc(-c2ccccc2)on1)N1CCC(n2cccc2)CC1 +CC1CCC(C)N(C(=O)Nc2cccc(N3CCOCC3)c2)C1 +CCCNS(=O)(=O)Cc1ccc(Cl)c(Cl)c1 +Cc1ccc(-c2nc(C)c(C(C)NC(=O)c3cc[nH]n3)s2)cc1 +Cn1c(N2CCC(CO)CC2)c(C#N)c(=O)n(C)c1=O +CCOc1ccccc1NC(=O)N1CCCC1c1c(C)noc1CC +Cc1ccc(C(C)NC(=O)CCC(=O)c2ccc(F)c(F)c2)o1 +CCn1c(=O)n(CC(=O)NCc2nc(C)sc2C)c2ccccc21 +O=C(NCCc1cc(Cl)cc(Cl)c1)c1ccoc1 +Fc1cncc(-c2nc(-c3ccc(OCc4cccnc4)cc3)no2)c1 +Cn1cc(C(=O)NCCOc2ccc(F)cc2)nn1 +Cc1cc(C(=O)NCC2COc3ccccc3O2)c(C)o1 +Cc1nscc1C(=O)NC(C(N)=O)c1ccc(F)cc1 +O=C(CC1CCCC1)Nc1ccc2[nH]c(=O)[nH]c2c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)OCc1ccccc1F +Cc1cccc(NC(=O)COC(=O)c2n[nH]c(=O)c3ccccc23)c1 +CCOC(=O)C(C)(NC(=O)CN1Cc2ccccc2C1=O)C(C)C +CCOC1CCCN(C(=O)NCc2ccc(C)cc2N(C)C)C1 +CCc1noc(CC)c1CNC(=O)Cc1ccccc1C +Cn1cnc2cc(C(=O)NCC(C)(C)c3ccncc3)ccc21 +O=C(OCC(F)F)c1ccc(=O)n(-c2ccc(F)cc2)c1 +CCN(C(=O)c1ccc(Br)c(F)c1)C1CC1 +COC(=O)c1cc(-c2c(C)nn(C)c2C)nc2c1c(C1CC1)nn2C +CCN(CCC(=O)OC)S(=O)(=O)c1cn(C)c(C)n1 +Cc1ccnc2nc(C(=O)N3CCCC3CC(C)(C)C)nn12 +CNS(=O)(=O)c1ccc(C(=O)NCCCN2CCCC2=O)cc1 +CN(Cc1ccccc1)C(=O)CNc1ccccc1F +COc1ccc(C(=O)N2CCCCC2Cn2cccn2)cc1OC +CN(C)C(=O)COCc1nnn2c1CN(c1ncccn1)CCC2 +O=C(CNC(=O)c1cc2ccccc2o1)OCc1ccccc1 +CNC(=O)C1CN(C(=O)C2CC2)CC1c1ccnc(N2CCCC2)n1 +CCn1cc(C(=O)NC(C(=O)OC)c2ccc(Cl)c(F)c2)cn1 +CC(=O)N1CCN(C(=O)CCCNC(=O)c2ccsc2)CC1 +Cc1noc(C)c1CN1C(=O)C(C)Oc2cccc(N)c21 +COc1ccc(C(=O)C2CC2)cc1S(=O)(=O)NCC(C)C +CC12CCC3C(CC(O)C45CC4CCC35C)C1CCC2O +Cc1cccc(C(=O)N2CCn3cnc(COCC4CC4)c3C2)n1 +Cc1cc(C)c(CNC(=O)COc2ccc(C#N)cc2)c(=O)[nH]1 +CC(=O)Nc1cccc(Nc2cccc3cccnc23)c1 +CC1CN(C(C)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)CCO1 +CCCS(=O)(=O)NCc1cc(OC)cc(OC)c1 +Cc1ccc(Br)c(NCc2ncc(C)o2)c1 +Cc1ccc(NC(=O)c2cnc3[nH]nc(C)c3c2)nc1 +CN(CC(F)(F)F)C(=O)c1cc(F)cc2[nH]cnc12 +CCCN(CC(F)(F)F)C(=O)c1cccc(C#N)c1 +CC(=O)N1CCN(Cc2ncccc2C(F)(F)F)C(C)(C)C1 +Cc1ccsc1-c1cccc(NC(=O)NCCc2ncnn2C)c1 +N#Cc1cccc(NC(=O)CCn2cc(Cl)ccc2=O)c1 +CCn1c(-c2cc(NC(=O)c3ccsc3)[nH]n2)cc2ccccc21 +CCC(CC)C(=O)NCc1ccc(NS(C)(=O)=O)cc1 +CCNC(=O)CN1C(=O)CSc2ccccc21 +NC(=O)C1CCCCN1Cc1nc2ccccc2n1C(F)F +COc1ccc(F)cc1CN1CCN(c2ccc3nncn3n2)CC1 +O=C(Cc1cccc(C(F)(F)F)c1)Nc1ccc2[nH]c(=O)ccc2c1 +CCN(CC(C)C#N)S(=O)(=O)c1ccc(C)cc1C +CCN(CC(C)C#N)C(=O)Cc1cn2ccsc2n1 +COc1cc(N)cc(CCC(=O)N2CCCC2)c1OC +C=CCn1c(SCC(=O)c2ccc(Cl)cc2)nnc1C1CC1 +Cc1ccccc1SCC(=O)Nc1cnc2c(c1)c(C)nn2C +Cc1c(C(=O)N(C)CCc2ccccn2)sc2ncn(C)c(=O)c12 +COC(=O)c1cn(Cc2ccco2)cc(C(=O)OC)c1=O +Cc1ccc(CNC(=O)N2CCC(CO)CC2)c(OCC2CC2)c1 +O=C(CCC(O)c1cccs1)Nc1cccc(Cl)c1 +Cc1ccccc1CC(C)NC(=O)c1cccc(NC(N)=O)c1 +CCC(CSc1ccccc1)NC(=O)NCc1ncn(C)n1 +Cc1n[nH]cc1NCc1cc(-c2ccccc2)cnc1-c1ccncc1 +O=C(NC1COc2ccccc2C1)c1ccc(=O)[nH]c1 +Cc1ccc2cc(COC(=O)C3CCCO3)c(=O)[nH]c2c1 +COC(=O)c1cccc(C(=O)N2CCCSc3ccccc32)n1 +Cc1ccc(CNC(=O)C(NC(=O)c2ccccc2)C(C)C)cc1 +CC(NC(=O)C1CC=CC1)c1nc(C(C)(C)C)cs1 +CC(Cc1ccccn1)n1cnc2ccccc2c1=O +O=C(Cn1cnnn1)N1CCC(Oc2ccccc2)CC1 +COc1ccc(C2N(C)C(=O)c3ccccc3N2C)cc1OC +CS(=O)(=O)N1CCOCC2(CCN(c3cnccn3)CC2)C1 +COC(=O)Cc1csc(NC(=O)COC2CCCC2)n1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)OC(C)C(=O)NC(C)(C)C +CNC(=O)C1CCCCN1S(=O)(=O)c1cccc(F)c1 +CN(CC(=O)NC(C)(C)C)Cc1nc2c(cnn2C)c(=O)[nH]1 +COCCOc1cc(C)ccc1NC(=O)c1ccc(C)nc1C +Cc1ccc(-n2nc(C(=O)Nc3cnn(C)c3)ccc2=O)cc1Cl +CC(C)(O)CN1CCN(C(=O)c2cc3cc(Cl)ccc3o2)CC1 +Cc1nn(C)c(C)c1CNC(=O)c1cc2ccccn2n1 +O=S(=O)(NCC(O)Cc1ccccc1)c1ccc2ccccc2c1 +Cc1nnc(SCc2ccccc2Oc2ccccc2)n(N)c1=O +CCCC(NC(N)=O)C(=O)NCC(C)(O)c1ccc(F)cc1 +Cc1ccc(C(=O)OCCCNC(N)=O)cc1C +CC(C)CNC(=O)c1coc(NC(=O)c2ccco2)n1 +O=C(CSc1ccc(F)cc1)NCC1(O)CCOc2ccccc21 +Cc1cccc(C(=O)NCc2cccc(N)c2)c1C +O=C(CN1C(=O)CCOc2ccccc21)NCc1ccccn1 +COc1ccc(C2=Nc3ncnn3C(c3cccs3)C2)cc1 +Cc1ccsc1CNC(=O)c1cc2c(cc1O)OCO2 +COc1ccccc1-c1nnc(SCCC(=O)N2CCCCC2)o1 +N#Cc1ccc(N(CC(N)=O)C2CCCC2)c(Cl)c1 +COc1cc(C)ccc1OCC(=O)Nc1ccccc1OC(F)F +Cc1ccc(NC(=O)N2CCN(C(=O)CCC(C)C)CC2)c(F)c1 +Cc1cccc(NC(=O)CN(C)C(=O)c2cc(Cl)ccc2F)n1 +O=C(c1cc(C2CC2)n[nH]1)N(Cc1ccc2c(c1)OCO2)C1CC1 +O=C(NCCCCOc1ccc(F)cc1)c1ccc2[nH]cnc2c1 +O=C(COc1ccccc1-c1nc[nH]n1)N1CCc2sccc2C1 +COC(=O)c1sccc1NC(=O)CN1Cc2ccccc2C1=O +CCC1=C(C(=O)OC)C(c2ccccn2)NC(=O)N1 +CC(C)(C)NC(=O)Nc1ccccc1Br +Cc1noc(COCC(=O)N(C)C2c3ccccc3-c3ccccc32)n1 +Nc1ncccc1OCCOc1ccc(Cl)cc1 +CC(=O)N1c2ccccc2CC1C(=O)Oc1ccc2cn[nH]c2c1 +N#CC(C1CCCCC1)N1CCN(C(=O)C2CC2c2ccco2)CC1 +c1ccc2nc(SCc3nnc(C4CC4)o3)ccc2c1 +CCN(CC)C(=O)CCCNC(=O)Nc1ccccc1 +C=CCNC(=O)N1CCC(Cc2nnc(SC)n2C)CC1 +CCCC(=O)N1CCCC1C(=O)Nc1ccc(-n2ccnc2)cc1 +CC(C)(C)OC(=O)N1CCN(CC(CO)c2ccccc2)CC1 +CCCc1nnc(SCC(N)=O)n1CC1CCCO1 +O=c1[nH]ccc2nc3ncnn3c(-c3ccc(Cl)cc3)c12 +COC(=O)C1CCCN1C(=O)c1cccc(F)c1N +Cc1cnc(NC(=O)c2ccc(SC(C)C)cc2)s1 +COC(=O)c1cc(-c2csc(NC(=O)c3cnn(C)c3C)n2)c[nH]1 +CC(C#N)OC(=O)CNC(=O)c1sc2ccccc2c1Cl +Cc1occc1COC(=O)c1cn(C)nc1C(C)(C)C +CN1CCN(C(=O)CCC(O)c2cccs2)CC1 +CCc1ccc(-n2cnnc2)cc1NC(=O)NCCCn1ccnn1 +O=C(c1ccccc1Cl)N1Cc2nn3nccnc3c2C1 +Cc1ccccc1COC1CN(C(=O)c2cc(CC(C)C)nn2C)C1 +COc1ccc(OC)c(NC(=O)c2cn(C)nc2OC)c1 +CCC(CO)NC(=O)COc1cc(Cl)ccc1Cl +CNC(=O)CN1CCN(C(=O)Nc2cc(Cl)ccc2C)CC1 +Cc1ccc2c(c1)nc(-c1cnc(N3CCOCC3)nc1)n2C +CC(C)Cc1noc(CN2c3ccccc3CC2C(N)=O)n1 +CC(=O)c1ccccc1OCCn1c(=O)c(C#N)c2n(c1=O)CCC2 +N#Cc1ccccc1CN1C(=O)COc2ccccc21 +CCc1onc(C)c1NC(=O)c1ccc2c(c1)nnn2C +COc1ccc(S(=O)(=O)NCCc2nccs2)cc1 +CCOC(=O)Nc1cccc(NC(=O)NCc2ncc[nH]2)c1C +CC(c1ccc(NS(=O)(=O)c2ccccc2)cc1)N1CCOCC1 +COCCNC(=O)CNc1ccc(C(=O)N2CCC(C)CC2)cc1 +O=S(=O)(N1CCCCC1)N(CCc1cccc(F)c1)C1CC1 +CC(Sc1ncc(-c2ccc(F)cc2)[nH]1)C(=O)NC(C)(C)C +COCCN1CCC2(C1)c1ccccc1S(=O)(=O)N2C +N#Cc1cc(N)cnc1NCCc1ccccc1F +CCC(C)n1ncc2c(C(=O)N3CCCCC3C(C)C)cc(C)nc21 +Cc1ccc(NC(=O)C2CCCCC2)c(NC(=O)C2CCOC2)c1 +COCC1CCCN(c2cc(Br)cc(F)c2C(N)=O)C1 +CC(Oc1ccc(F)cc1Cl)C(=O)Nc1ccc(C(N)=O)cc1 +CCOC(=O)N1CCC(NC(=O)Cc2ccc3ccccc3c2)CC1 +NC(=O)c1cccc(CNCc2ccccc2C(F)(F)F)c1 +OCc1cc(Br)cnc1-n1ccc(C2CC2)n1 +COCCOc1ccccc1NC(=O)c1occc1C +CCCC1CN(C(=O)Nc2ccc(F)c(C(=O)N(C)C)c2)CCO1 +Cc1cc(C(=O)NCCc2nc3ccccc3s2)[nH]n1 +NS(=O)(=O)CCNC(=O)c1cc2ccccc2s1 +COc1ccc(OS(=O)(=O)c2ccc3c(c2)CCC3)cc1 +CCCc1nnc(SCC(=O)N2C(C)CCCC2C)n1CC +CC(=O)NCCNC(=O)CCC(=O)c1cccs1 +CC(=O)Nc1ccc(CCC2(NC(=O)C3CC3)CCCCC2)cn1 +COc1ccc2c(c1)OCC(C(=O)N1CCC(O)(C(F)(F)F)C1)C2 +NC(=O)C1CCCN(C(=O)Cn2cnc3ccccc32)C1 +c1ccc(CSc2nnc(SCc3ccccn3)s2)nc1 +COc1cc(C#N)ccc1OCCS(=O)(=O)c1ccccc1F +O=C(NCCc1ccccc1)C1CC(=O)N(Cc2ccc(F)cc2)C1 +CC(C)c1noc(CCCC(=O)NCC(=O)N2CCCCC2)n1 +CCCc1c(C(=O)N2CCN(C(C)=O)CC2)[nH]c(C)c1C(=O)OC +Cc1csc(CSc2nnnn2-c2ccc(C(C)C)cc2)n1 +CCC(C)NC(=O)N(C)Cc1cccc(C(N)=O)c1 +Cc1ccc(C(=O)N(C)CC(=O)Nc2cccc(F)c2)cn1 +COc1ccccc1CCC(=O)Nc1nnc(C2CCCO2)s1 +CCOCc1nc(-c2cn(C)c3ccccc23)n(C)n1 +O=C(C1CC1)N(Cc1ccc2c(c1)OCCO2)C1CC1 +O=C(Nc1ccnc(OC2CCOC2)c1)c1cc(F)ccc1F +Cc1[nH]c2ccnn2c(=O)c1CC(=O)N(CC1CC1)C1CCCCC1 +O=C(Nc1ccc(Cl)cn1)c1[nH]nc(C2CC2)c1Br +O=C(c1ccncc1)N1CC2CCC(C1)N(C(=O)N1CCOCC1)C2 +O=C(CCC1N=C(O)N(Cc2ccccc2)C1=O)NCc1ccco1 +CNC(=O)c1cc(NC(=O)N(C)C(C)c2ccc(F)cc2)ccc1F +CCN1Cc2cccc(C(=O)Nc3cccc(OC)c3)c2C1=O +CCn1nc(-n2cnnc2)c(NC(=O)c2ccc3c(c2)OCO3)c1C +CCCCNC(=O)NCC1COc2ccccc2C1 +Cc1cc(C(=O)N(C)Cc2cccc(Cl)c2)on1 +COc1nn(C)cc1C(=O)N1CCN(CC(O)c2ccco2)CC1 +CC(NC(=O)CCOc1ccc(F)cc1)c1nnc2n1CCC2 +Cc1nc(CN(C)C(=O)c2cccc(-c3ccoc3)c2)cs1 +Cn1[nH]c(=O)c2c(C(=O)NCCCn3cccn3)cc(C3CC3)nc21 +CNS(=O)(=O)c1ccc(C(=O)Nc2cc(C)ccn2)cc1 +O=C(Nc1ccc(F)cc1)C1CCCN(C(=O)NC2CC2)C1 +NC(=O)c1ccc(COC(=O)Cc2ccc(F)cc2)cc1 +CCn1nc(C(=O)Nc2ccc(F)cc2)c(=O)c2ccccc21 +COc1cccc(OCC(=O)Nc2nnc3n2CCCS3)c1 +CCOc1ccc2ccccc2c1C(=O)NCCC(O)c1ccco1 +CC(C)(CO)CCCNC(=O)N1CCc2c(F)ccc(F)c2C1 +CCc1cnc(N2Cc3cnn(CCO)c3C2)nc1 +CN(Cc1ccnn1C)C(=O)c1cccc(Oc2ccccc2)c1 +Cn1cc(C(=O)Nc2ccncc2)c(C(=O)Nc2ccncc2)n1 +CC1CN(C(C)C(=O)NC(c2ccccc2)c2ccccc2)CCO1 +COc1ncnc2c1CN(Cc1cnc3cnccn13)CC2 +CNS(=O)(=O)c1ccc(C(C)NCCc2csc(C)n2)cc1 +O=C(NC1CCCc2ccccc21)c1cccnc1 +Fc1ccc(CNc2ccccc2Cn2cncn2)cc1 +Cc1ccc(CCN(CC2CCCO2)C(=O)c2cc(C)no2)cc1 +CCOCCC(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +Cc1c(C(=O)N(C)Cc2ccco2)nnn1-c1cccc2cccnc12 +N#Cc1nnn(CCCOc2ccccc2)c1C1CC1 +O=C1CC2CCC(C1)N2c1ccccc1OC(F)F +CCCn1nnnc1Cn1cnc2c(C)cccc2c1=O +Cc1cccc(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)n1 +CN(C)C(=O)CCCC(=O)c1ccc(Br)cc1 +COc1ccc(CNc2cnn(CC(F)F)c2)c(Cl)c1OC +CCOCCC1(CNC(=O)c2ccco2)CCC1 +CC=Cc1ccc(OCC(=O)Nc2sccc2C#N)c(OC)c1 +CC1CCc2nn(CC(=O)Nc3cc(F)ccc3F)c(=O)cc2C1 +CCN(CCO)C(=O)CCNC(=O)c1ccc(F)cc1F +Cc1c(C(=O)NCc2cccc(Cl)c2)cnn1-c1ccncc1 +CCOC(=O)C1CCN(C(=O)c2ccc(C)c(C)c2O)CC1 +CC(NC(N)=O)C(=O)N(C)CCCc1cc(-c2ccc(F)cc2)n[nH]1 +CCOC(C)c1noc(CN(C)Cc2c(C)noc2C)n1 +CCOc1ccccc1NC(=O)c1ccc(C(N)=O)cc1 +Fc1cnc(N2CCC3(CC2)COC(COc2cccnc2)C3)nc1 +Cc1c(C(=O)Cn2cnc(C#N)n2)sc2ccccc12 +Cc1nc2ccccc2c(=O)n1CCCC(=O)N1CCOCC1C +COCCOc1c(Cl)cccc1NC(=O)c1ccco1 +Cc1nc(-c2csc(S(=O)(=O)N3CCCCCC3)c2)no1 +CN(Cc1csc2ccccc12)C(=O)Nn1cnc2ccccc21 +CCS(=O)(=O)N(C)C1CCN(C(=O)c2c(F)cccc2F)CC1 +O=C(CCc1cc2n(n1)CCCN(c1ncccn1)C2)N1CCCC1 +O=C(NCc1ccnc(OCc2ccccc2)c1)c1ccc(F)nc1 +O=C(Cc1csc(Nc2ncnc3ncccc23)n1)c1ccccc1 +O=C(Cc1ccccc1)c1cccc(C2OCCCO2)c1 +COC(=O)c1sccc1S(=O)(=O)N1CCOc2ccccc21 +CCCN(CC1CC1)c1cc2c(cc1N)CC(=O)N2 +COCCNC(=O)CC(C#N)c1cccc(Br)c1 +O=C(NCc1ccc(C(F)(F)F)cc1)NCc1ccccn1 +N#Cc1ccc(C(=O)Nc2ccc(-n3cccn3)cc2)cc1 +CCC(Sc1ncn[nH]1)C(=O)NCc1ccccc1 +Cc1nc2n(n1)CCN(C(=O)c1cc(C(C)(C)C)n(C)n1)C2 +CC1NCc2ccccc2C1NC(=O)Cc1cccs1 +CC(=O)N1CCN(C(=O)CCNC(=O)CC2C=CCC2)CC1 +CC(=O)NCCNC(=O)Cn1cnc2c(cnn2C)c1=O +O=C(c1ccc(OCc2ccon2)cc1)N1CCCC1 +O=S1(=O)CCCN1c1ccccc1C(F)(F)F +Cc1cc(=O)oc2c3c(c(Cl)cc12)OCN(C(C)C)C3 +Cc1oc(-c2ccccc2)nc1Cn1cnc2oc(C)c(C)c2c1=O +Cc1cc(C(=O)NCC(=O)Nc2ccc(C(C)C)cc2)n(C)n1 +CN(C)c1ccc(C(=O)NCCn2ccc(-c3ccncc3)n2)cc1 +O=C(CCc1ccsc1)NCC(O)c1cccc(F)c1 +Cc1cc(=O)[nH]c(SCC(=O)NC(C)c2ccccc2)n1 +OCc1nnn(Cc2ccccc2Cl)c1-c1ccccc1 +CNC(=O)c1ccc(CN(C(=O)c2cc(C)nn2C)C2CC2)cc1 +CCN(CC1COc2ccccc2O1)C(=O)Nc1ccnn1C(C)C +CC1CN(C(=O)COc2ccc(F)cc2F)CC(C)O1 +COC1CCN(S(=O)(=O)c2cn(C)cn2)C1Cc1cccnc1 +Nc1cc(NC(=O)Cc2ccc(Cl)cc2)ccc1F +CCc1cc(N(C)Cc2cc(C3CC3)[nH]n2)n2nccc2n1 +O=C(Nc1nncs1)c1cccc2c1-c1ccccc1C2 +CC(=O)N(C)CC1(c2ccc(Br)cc2)CC1 +CC(=O)Nc1ccc(S(=O)(=O)NCC2(O)CCCC2)cc1 +O=C(OCC(=O)N1CCN(c2ccccc2F)CC1)c1ccoc1 +Cc1cc(C)cc(C(=O)NCc2nnnn2-c2ccccc2)c1 +CC(C)(C(=O)N1CCC(C(N)=O)CC1)c1ccc(Cl)c(Cl)c1 +COC(=O)N1CCC(Nc2ccc(Cl)c(C#N)n2)CC1 +CCOC(=O)CNc1ccccc1S(=O)(=O)CC +Cc1csc(NC(=O)C(C)Oc2ccccc2)n1 +CCCNC(=O)c1ccc(-c2cc(F)ccc2OC)nc1N +CCOC(=O)c1ccccc1-n1ccnc1C(=O)NC1CC1 +O=C(CCNS(=O)(=O)c1ccccc1)Nc1ccc2c(c1)OCO2 +CC(c1ccco1)N(C)S(=O)(=O)c1cc(Cl)ccc1C#N +O=S1(=O)CCCCN1CCOc1ccccc1Cl +CCOCCS(=O)(=O)Nc1ccc2c(c1)CCCN2 +CCCc1nc(CN2CCOC(C(N)=O)C2)cs1 +CCC(=O)Nc1ccc(NC(=O)NC(CC)CO)cc1 +CCOc1ncccc1C(=O)N1CCCc2cc(OC)ccc21 +O=C(CCNC(=O)c1cnn2c1CCCC2)NCc1ccccn1 +COc1ccc(NC(=O)c2ccc3c(=O)n4c(nc3c2)CCC4)cc1 +O=C(CCn1nc2ccccn2c1=O)N1CCOc2ccc(F)cc21 +CC(=O)c1ccccc1NC(=O)CCN1CCOC1=O +C=CCCOC(C)C(=O)N(C)C1CCN(c2ccccc2)C1=O +Cc1cccc(C(C)C)c1NC(=O)CSc1nc(=O)[nH]nc1C +CC(C)N(C(=O)C1CC1c1ccccc1)C1CCOCC1 +C#CCN(CC#C)Cc1c(C)n(C)n(-c2ccccc2)c1=O +CCCCNC(=O)CCn1c(=O)sc2ccccc21 +CC(=O)c1c(C)nc2nc(-c3cccnc3)nn2c1C +CCn1c(SCc2nccn2C(F)F)nc2ccccc2c1=O +CC(Oc1ccc(C(C)C)cc1)C(=O)N1CCN(CCC#N)CC1 +COc1ccc2c(OC)c3ccoc3nc2c1OC +O=C(Nc1ccccc1O)c1ccc(Cn2cccn2)cc1 +CN(Cc1ccsc1)C(=O)c1cc(N)cn1C1CC1 +CCN(CCC(=O)OC)C(=O)c1cc(Cl)ccc1O +Cc1cccc(C(=O)Nc2ccccc2-n2ccnc2)c1 +Cc1cc(C)c(S(=O)(=O)N2CCOCC2)c(C)c1N +CC1C(=O)NCCN1C(=O)CCc1ccccc1O +COc1cnn(-c2cccc(Cl)c2)c(=O)c1Cl +CCCCN(C)C(=O)Cn1nc2ccccn2c1=O +CCN(C)c1ccc(C(=O)NCCC(=O)NC2CCCCC2)cc1 +C=CCNC(=O)c1ccc(N(C)S(=O)(=O)c2cccs2)cc1 +Cc1ccccc1-n1ncc2c(O)nc(SCC(N)=O)nc21 +COCCN(Cc1ccccc1Cl)c1ncnc2oc(C)nc12 +Cn1nc(C(=O)NCc2cccs2)cc1C(F)(F)F +CCN(C(=O)NCCN1CCN(c2ncccn2)CC1)C(C)C(C)C +CN(C(=O)Cn1cnnn1)C1CCN(c2ccccc2Cl)C1=O +COCc1nc(C(=O)N2CCCCCC2c2ccc(C)o2)cs1 +O=C(c1cc(C2CC2)on1)N1CCN(Cc2ccsc2)CC1 +Cn1ccc(=O)c2c(-c3ccccc3)nc3nonc3c21 +CC1CCCCN1S(=O)(=O)c1ccc2c(c1)CCN2 +Cc1cc(NC(=O)C2(C)CC2(Cl)Cl)ccn1 +O=C(Cc1ccc[nH]1)Nc1ccccc1OC(F)(F)F +COc1ccc(-n2nnc(C#N)c2-c2ccncc2)c(OC)c1 +CC(=O)c1nnn(-c2ccc(Oc3ccccc3)cc2)c1C +Fc1ccc(OCc2nnc(SCc3noc(C4CC4)n3)o2)cc1 +CC(C)(CO)Nc1nnnc2c1cnn2-c1ccccc1 +CCc1cc2c(NCCOCC(C)C)ncnc2s1 +COCCNC(=O)C(C)n1ncc2c1c(C)nn2C +CC(NC(=O)c1ccco1)C(=O)OC(C)c1ccc(F)cc1F +CCc1noc(CNc2cc(Cl)ccc2C(=O)N(C)C)n1 +CCOCCNC(=O)NCc1cccc(S(N)(=O)=O)c1 +Cc1cc(N)ccc1NC(=O)COc1cccc(C)c1C +Cc1nc(CC(=O)Nc2ccccc2OCCC(N)=O)cs1 +Cc1ccc(Cc2nnc(C(=O)NCc3ccccn3)o2)cc1 +Cc1ccc(OCC(=O)Nc2nc3ccccc3n2C)cc1 +CC(C)c1nc(CNc2cccc3c2OCCO3)cs1 +Cc1ccc2ncc(C(=O)Nc3ccc(Cl)cc3)c(=O)n2c1 +Cn1c(C(=O)NCC2CCCO2)cc2c(F)cccc21 +O=C(CSc1n[nH]c(=O)[nH]c1=O)c1cccs1 +CC(Oc1ccc(F)cc1Br)C(=O)N(C)C(C)C +COCCN(CC(=O)N(C)C)C(=O)c1ccc(C)c(OC)c1 +Cc1ccc2ncc(C(=O)Nc3cncc(-c4nncn4C)c3)n2c1 +O=c1c2ccccc2ncn1CCOCCOc1ccc(F)cc1 +Cc1noc(NC(=O)c2cnc3sccn3c2=O)n1 +COc1ccc(NC(=O)N2CCn3nc(-c4ccccc4)nc3C2)cc1 +CC(C)CNC(=O)C1CC(=O)N(C2CCC(C)CC2)C1 +Cc1cncc(C(=O)N2CCCCC2c2nc[nH]n2)c1 +N#Cc1ccc(F)c(COC(=O)c2cccc(O)c2)c1 +CCc1ccc(OC)c(S(=O)(=O)N2CCOCC2)c1 +COCc1cc(C(=O)Nc2ccc(C(C)=O)c(C)c2)ccc1F +COc1cccc(CC(=O)N(CCC#N)c2ccccc2)c1 +CCOc1cc(C)c(Cl)cc1S(=O)(=O)NCc1cccnc1 +CCCOc1cccc(C2C(C(=O)OCC)=C(C)Nc3nnnn32)c1 +Cc1cnc(CNc2ncc(-c3ccc(F)cc3)cn2)cn1 +O=C(CCCNC(=O)C1CC1)Oc1ccc(F)cc1 +CC(=O)N1CCCC(Cc2ccc(C(=O)N(C)C)nn2)C1 +COC(=O)c1ccc(=O)n(Cc2c(F)cccc2Cl)c1 +COC(=O)c1n[nH]cc1-c1cc(-c2ccc(C)o2)nc(N)c1C#N +O=C(CCc1ccsc1)NC1CCCN(c2ccccc2F)C1=O +CCc1cc(C#N)c(NC(=O)c2cc(-c3ccccc3)no2)s1 +CCc1cccc(C)c1NCCC(O)c1ccccc1 +Cc1ccc(Cc2nnc(NC(=O)c3ccc(C)cc3)o2)cc1 +CCCC1CN(C(=O)c2ccc(C)nc2C)CCO1 +Cn1ncc(Cl)c1C(=O)NCCc1ccc(Cl)cc1 +CCn1cc(CN2CCN(c3cnn(C)c3)C(=O)C2)cn1 +CCCCN(CCO)C(=O)Nc1nnc(C(F)(F)F)s1 +COc1ccc2c(cnn2CCC(=O)Nc2ccc(C(C)=O)cc2)c1 +O=C(CCCCn1c(=O)[nH]c2ccsc2c1=O)N1CCCCC1 +CC(Sc1ncc(-c2ccccc2)n1CC1CCCO1)C(N)=O +CCOC(=O)CCC(C)(c1ccc(O)cc1)c1ccc(O)cc1 +CC#CCn1nnc(-c2ccc(OC)c(OC)c2)n1 +COCC1c2c(cnn2CC2CC2)CCN1C(=O)c1ccoc1 +CC(NC(=O)COc1ccc(CO)nc1)c1cccs1 +CC1CN(CCS(=O)(=O)c2ccccc2)CC(C)O1 +C=CCN(Cc1cc(=O)n(C)c(=O)n1C)c1nc2c(s1)CCCC2 +CCC(=O)Oc1cc(OC(=O)CC)c2c(C)cc(=O)oc2c1 +CC(CCc1ccccc1)NC(=O)Cc1nnc(-c2ccccn2)o1 +O=C(NC(NCC1CCCO1)C(Cl)(Cl)Cl)c1ccco1 +CC(CCc1ccccc1)NC(=O)C1CCCN1C(=O)C1CC1 +O=C(c1cnc2ccccn12)N1CC=C(c2cccs2)CC1 +CCC(=O)Nc1c(-c2ccccc2)nc2ccccn12 +CC(C)(C)OC(=O)N1CCC(C2CCCC(O)C2)CC1 +CC(C)c1noc(-c2ccc(NC(=O)c3ccnnc3)cc2)n1 +CNc1snc(C)c1C(=O)N1CCCC(c2ccn[nH]2)C1 +COc1ccc(-c2nc(C)c(C(=O)Nc3cnn(C)c3)s2)cc1 +CN(CCOCC1CC1)C(=O)Cc1c[nH]c2ccc(F)cc12 +CCOc1ccc(NC(=O)CN(C)C(=O)c2ccccc2)c(C)c1 +COCC1CCN(C(=O)Nc2cc(-n3cccc3)ccc2F)CC1 +Cc1cc(C(=O)NCCS(N)(=O)=O)ccc1F +Cc1ccn2ncc(C(=O)NCCNC(=O)C(C)C)c2c1 +COc1cccc(C(C)NC(=O)COC(=O)c2ccccc2Cl)c1 +CCCC(=O)Nc1nc2ccc(S(=O)(=O)N(C)C)cc2s1 +CCNC(=O)N1CCC(Oc2cccc(-c3cccnc3)c2)CC1 +COc1cccc2c(C)cc(-n3ncc(C#N)c3N)nc12 +CC(c1ccon1)N(C)C(=O)Cn1ccc2ncccc2c1=O +O=C(Nc1ccn(CCc2ccccn2)n1)c1cccc2cccnc12 +Cc1ccc(C)c(OCCC(=O)OCc2nc(C)no2)c1 +COc1ccccc1C(NCc1nc(C)cs1)c1ccccn1 +CCOc1ncccc1C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1ccccc1NC(=O)N1CCCC(C(N)=O)C1 +C#Cc1cccc(NC(=O)c2cnn(-c3ccccc3)n2)c1 +O=S(=O)(NCCN1CCOCC1)c1ccccc1C(F)(F)F +Cc1ccc(CC2Oc3ccc(N)cc3N(CCO)C2=O)cc1 +Cc1cc(-c2nnc(CN3CC(C)OC(C(N)=O)C3)o2)c(C)o1 +O=C(NCC(c1ccccc1)N1CCOCC1)c1cccs1 +CN(Cc1ccc(F)cc1)C(=O)NCc1nnc2n1CCCCC2 +Cc1cc(NC(=O)c2sc(Nc3ccccc3F)nc2N)on1 +CCOC(=O)N1CCN(C(=O)c2ccccc2OC)CC1 +O=C(Nc1cccn(CC(F)(F)F)c1=O)N1CCOCC1C1CC1 +Cc1c(N)cccc1C(=O)OCCc1ccccc1 +O=C(c1ncccn1)N1CCC2(CCCC(CN3CCOCC3)O2)C1 +Cc1cccc(C2Nc3ccccc3C(=O)N2c2ccccc2)n1 +CCn1nc(C)c(NC(=O)CNC(=O)c2cc(C)n(C)n2)c1C +COc1ccc(-c2cnc(N)nc2)c(-n2nc(C)cc2C)c1 +CCOc1cc(S(=O)(=O)n2cccn2)ccc1F +Cc1ccc(Sc2nn(C)c(=O)n(C)c2=O)cc1C +COc1ccc2cc(CN(C)C(=O)CSc3ncn[nH]3)ccc2c1 +CC(=O)N(C)c1nnc(C23CC4CC(CC(C4)C2)C3)s1 +CCN(Cc1ccncc1)C(=O)C1CCCN(C(=O)COC)C1 +COC1CCCN(C(=O)CCN2C(=O)COc3ccccc32)C1 +CCc1ccc(C(O)CCCC(=O)N2CCOCC2)cc1 +Cc1cc(NC(=O)CC2OCCc3ccccc32)c2ncccc2c1 +CCN(CC)C(=O)CNc1cc(C(=O)N2CCOCC2)ccc1OC +Cc1csc(CNC(=O)NC(C)Cc2ccco2)n1 +O=C(CCn1c(=O)oc2ccccc21)NCCN1CCCCCC1=O +CC(C)COc1ccc(C(C)(C)C(=O)NCc2csc(=O)[nH]2)cc1 +COC(=O)c1ncccc1OCc1nc(C)c(C)s1 +COc1ccc(S(=O)(=O)N(C)C(C)C#N)cc1C +Nn1c(=O)n(CC(F)(F)F)c(=O)n(CC(F)(F)F)c1=O +Cc1ccc(S(=O)(=O)NCCC(=O)NC(C)C(C)C)cc1C +Cc1cnc(CN(CCO)c2cccc(F)c2)o1 +CC(C)NC(=O)NC1CCCN(c2ccccc2F)C1=O +CCC(CC)C(=O)NCc1c(C)nn(-c2ccccc2)c1C +Cc1cnn(CCC(=O)Nc2cccc(C(=O)N3CCCC3)c2)c1 +Cc1cccc(N)c1NS(=O)(=O)C1CCOCC1 +COc1cc(C(=O)N2CCC(C(=O)N(C)C)CC2)ccc1C +CC(C)c1noc(CNc2cc(Cl)ccc2C(N)=O)n1 +CCNC(=O)CNC(=O)NCc1ccnc(OC(C)(C)C)c1 +NC(=O)C1CCN(C(=O)CCOc2cccc3ccccc23)C1 +Cc1cc(NC(=O)c2cccc(F)c2)c2ncccc2c1 +COCCC(C)(C)CNC(=O)c1sc(C(C)C)nc1C +O=C(CSc1nnnn1C1CCCC1)Nc1cccc(F)c1 +Cc1noc(C)c1CCC(=O)N1CCC(CO)CC1 +COC1(C)CC(N(C)C(=O)c2cnn(-c3ccncc3)c2C)C1(C)C +CCN1CCOC(CCNC(=O)c2ccccc2NC)C1 +Cc1oc(-c2cccs2)nc1C(=O)NCC(C)N1CCOCC1 +CC(C)(C)CCS(=O)(=O)N1CCOCC1C1CC1 +CC(=O)c1sc(NC(=O)c2ccc(S(C)(=O)=O)cc2)nc1C +COc1ccc2oc(C(=O)N3CC(C)OC(C)C3)c(C)c2c1 +C=C(C)CN(CC)C(=O)C(C)Oc1ccc(-c2nnco2)cc1 +COC(=O)c1c(C)oc2ccc(OCC(=O)OC(C)C)cc12 +COCc1cc(=O)[nH]c(N2CCN(c3ccc(Cl)cc3)CC2)n1 +C#Cc1cccc(NC(=O)NCC2CN3CCCCC3CO2)c1 +O=C(Nc1ccccc1N1CCCC1=O)c1cccc(C(F)(F)F)c1 +O=C(NC1(c2ccccc2)CCC1)c1cnc(-c2ccccc2)nc1 +Cc1cnc(NC(=O)NCc2ccnc(OC3CCCC3)c2)s1 +Clc1ccc(CNc2nnc3n2CCCCC3)cc1 +O=C(NCCOc1ccccc1)Nc1cc(N2CCOCC2)ncn1 +CC(=O)NCc1ccc(C(=O)OCC(=O)C2=NC=CC2)cc1 +Cc1ccc(N2C(=O)c3ccccc3NC2(C)C)cc1 +COC(=O)c1ccc2c(c1)nc(CC#N)n2C1CC1 +Cc1ccc(C(=O)N2CCC(C(=O)Nc3nc(C)cs3)CC2)cn1 +CCCOCC(=O)Nc1ccc(-c2ncn(C)n2)cc1 +COc1ccc(OC)c(NC(=O)c2ccc3ccccc3n2)c1 +COc1cccc(-c2nc(C(=O)N3CCOCC3)cs2)c1OC +C#CCN1CCN(C(=O)NCc2c(CC)noc2CC)CC1 +CCCNC(=O)CN1C(=O)CSc2ccccc21 +CCc1ccc(C(=O)Nc2cccc(C(=O)N(C)C)c2)cc1 +COc1ccc(-c2nc3ccc(F)cn3c2CC#N)cc1OC +CCN(Cc1ccncc1)C(=O)Nc1ccccc1Cl +Cc1ncccc1C(=O)NC(Cn1nnc2ccccc21)C(C)C +COc1ccc2c(c1)nc(CO)n2Cc1nccn1C +Cc1ccc(C(=O)NC(C)c2nnc3n2CCCCC3)o1 +COCC(NC(=O)N(C1CC1)C(C)c1ccco1)c1ccc(C)o1 +Cc1noc(C2CCCN2C(=O)c2cc3ccccc3oc2=O)n1 +CCCn1ncc(C(=O)N(C)C(C)c2nc(C)sc2C)c1C +Cc1cc(C(=O)N2CCN(C3CCCC3O)CC2)c2[nH]ncc2c1 +OC1CC2CCC(C1)N2c1ncc(Br)cn1 +O=C(C1CC1c1cccc(F)c1)N(Cc1ccco1)CC1CCCO1 +CCC(C)NC(=O)C(C)NC(=O)NCC1CCCOC1 +CCN(CC)C(=O)CCCNC(=O)Nc1c(C)cc(C)cc1C +Cc1cccc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)c1C +Cc1noc(C)c1S(=O)(=O)NCC1(O)CCOCC1 +CCc1cccc(CC)c1NC(=O)C1CC(=O)N(CCOC)C1 +CCCC(=O)NCC(Cc1cccc(F)c1)N1CCCC1=O +Cc1ccc(C(C)OC(=O)Cn2c(=O)[nH]c3ccccc3c2=O)cc1 +CC(C)CCNC(=O)N1CCN(C(=O)c2ccco2)CC1 +CNC(=O)COc1ccc(S(=O)(=O)NCC2CCCO2)cc1C +COc1cccc(OCC(=O)Nc2ccccc2C(N)=O)c1 +CCC(C)(O)CNC(=O)Nc1ccc(OC)cc1 +N#CC1(C(=O)N2CCCN(Cc3cccs3)CC2)CCCCC1 +C#CCOCC1CCCN(C(=O)CNC(=O)c2ccccc2)C1 +COC(=O)CN(C(=O)CSc1ccncc1)C(C)C +COc1cc2c(cc1OC)C(c1ccc(OC(C)C)cc1)CC(=O)N2 +CC(NC(=O)c1ccc(=O)[nH]c1)c1cccc(F)c1 +COc1ncccc1C(=O)Nc1ccc(-n2cc(C#N)c(N)n2)cc1 +CSc1ccc(OC(=O)Cn2ccc(=O)n(C)c2=O)cc1 +Brc1ccccc1NCc1cccnc1 +COc1cc(=O)[nH]c(SCC(=O)Nc2ccccc2C#N)n1 +O=C(NCc1ccccc1Cl)c1cnc(N2CCOCC2)nc1 +Cc1nn(C)c(C)c1CC(=O)NC1CCCN(c2cccnc2)C1=O +CNC(=O)c1cc(NC(=O)Cc2ccc(F)c(F)c2)ccc1F +COc1ccc(C2CC(NC(C)=O)CC(C3CCCCC3)O2)cn1 +NC(=O)c1ccc(NCCCc2c[nH]c3ccccc23)cc1 +Cc1cccc(NC(=O)c2c[nH]c3ccc(F)cc3c2=O)c1C +CN(Cc1ncnn1C)Cc1nnnn1-c1ccccc1 +CCc1ccsc1-c1nc(C(C)(C)NC(C)=O)no1 +COC(=O)CSc1nnc(C)n1Cc1ccccc1 +O=C(CNC(=O)OCc1ccccc1)OC1CCCC1 +COc1c(F)cc(NC(=O)c2ccc(=O)n(C)c2)cc1F +O=C(CCc1ccccc1)Nc1ccc(CN2CCOC2=O)cc1 +COc1ccc(C(=O)CNC(=O)CC(C)C)cc1C(C)C +COc1ccc(NC(=O)N2CCNC(=O)C2)cc1C +CCCn1c(C)nnc1SCCc1ccncc1 +CC(C)CN(C(=O)CSc1nc2ccccc2n1C)C1CC1 +COC(=O)NCC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +Cc1ccccc1CN(C)C(=O)c1cc(C2CC2)[nH]n1 +CC(O)(CNC(=O)Cn1nc2ccccn2c1=O)c1cccs1 +OCCc1csc(COc2cccc3c2CCCC3)n1 +Cn1cccc1CNc1cnn(-c2cccc(C(F)(F)F)c2)c1 +Cc1cc(C(=O)Nc2cc(S(N)(=O)=O)cc(C)c2C)[nH]n1 +O=C(NCc1cnn(Cc2ccccc2)c1)Nc1cccnc1 +Cc1ccccc1CNC(=O)Cc1c(C)noc1C +CC(C)(C)c1ncc2c(n1)CN(C(=O)CCNS(C)(=O)=O)C2 +CCNC(=O)NCCN1CCN(S(C)(=O)=O)CC1 +CN(Cc1nccs1)C(=O)CCCc1cc(F)ccc1F +CNC(=O)c1n[nH]c2c1C(c1coc(C(C)C)n1)CC(=O)N2 +O=c1cc(C2CCC2)ncn1Cc1cccc(OC(F)F)c1 +COc1ccc(CNC(=O)CN2CCOC(C)C2)cc1OC +CC(NC(=O)c1cc(Cl)ccc1O)C(=O)NCc1ccccc1 +CCc1cnc(CN(C)C(=O)NCc2cnc(C)s2)s1 +O=C(CCc1nnc(-c2ccccc2)o1)Nc1nc2c(s1)CCC2 +CC(=O)NCC1CCN(C(=O)Cc2ccc3c(c2)CCCC3)CC1 +Cc1ccc2[nH]c(=O)c(-c3noc(-c4cccs4)n3)cc2c1 +CC(=O)N1CCc2cc(C(=O)Nc3ccc(C)cc3)ccc21 +COC1CCN(C(=O)Nc2ccccc2Cl)CC1 +CN(C)C(=O)N1CC2CCC(C1)C2C(=O)NCCc1cccs1 +COc1ccc(NC(=O)CCCc2nc3ccccc3[nH]2)cc1 +Cc1ncsc1C(=O)N1CCCC(CNS(C)(=O)=O)C1 +COc1cccc(Nc2ccccc2C(=O)NCc2ccnn2C)c1 +Cc1cc(NC(=O)C2CC(=O)N(c3ccc(F)cc3F)C2)ccn1 +COc1ccc(CNc2cccc(NC(C)=O)c2)c(Cl)c1O +CC1=Nc2nc(-c3cccnc3)nn2C(c2cccs2)C1C(N)=O +Cc1ccc(C(C)NC(=O)C(C)Sc2ccccn2)o1 +O=C(c1ccccc1)C1CCN(S(=O)(=O)c2cccs2)CC1 +O=S(=O)(NCCCN1CCOCC1)c1ccccc1F +CCn1nc(C(=O)NCCO)c(=O)c2ccccc21 +CC(NC(=O)C1CCC1)C(=O)Nc1ncc(Cc2ccccc2)s1 +CCCn1c(C)nnc1SCC(=O)N1CCOC2CCCCC21 +CCN(Cc1ccccc1)C(=O)c1cnc(C)nc1N +CN(C)c1ccc2c(c1)C(c1cc(=O)cc[nH]1)NCC2 +CCC(COC)NC(=O)c1ccc(-n2ccnc2)cc1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)N(C3CC3)C(C)C3CC3)c12 +COc1ccccc1NC(=O)Nc1ccc(-n2nnn(C)c2=O)cc1 +CCCc1cc(C(=O)Nc2cccc(NC(C)=O)c2C)[nH]n1 +OCCn1c(CO)nc2cc(Br)ccc21 +Cn1c(=O)[nH]c(=O)c2c1nc(NCc1ccccc1)n2CCO +CCOC(=O)Cc1csc(NC(=O)c2cccc(C)c2)n1 +CCOC(=O)CN(C(=O)C1CCC(=O)N1)C(C)C +Cc1cc(C)cc(C(=O)N2CCCC(C(=O)OC(C)C)C2)c1 +Cc1ccc(-c2n[nH]c(NC(=O)c3n[nH]c(=O)c4ccccc34)n2)cc1 +O=C(Nc1n[nH]c(-c2ccoc2)n1)c1ccc(-c2cscn2)cc1 +O=C(NCCc1ccccc1F)c1cc2ccccn2n1 +C=CCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1 +CC(C)Oc1ccccc1NCc1cccc(O)c1 +CCN(Cc1cccc(OC)c1)C(=O)c1n[nH]c(N)n1 +CSc1ncc(C(=O)NCc2ccc(OC(C)C)cc2)c(C)n1 +Cc1ccc(C)c(CNC(=O)CCn2c(C)cccc2=O)c1 +Cc1ccc(C)c(OC(=O)Cc2csc(C)n2)c1 +COc1cccc(-c2cc(C#N)c(NC(=O)c3ccco3)o2)c1 +CCOC(=O)CNC(=O)N=c1[nH]nc2cccc(OCC)n12 +CC(C)(C)NC(=O)c1snc(-c2ccncc2)c1N +CCCOc1nn(CCC)cc1C(=O)N1CCC(C(N)=O)CC1 +Cc1ccc(C)c(OCc2nnc3c(N)cc(C)cn23)c1 +COc1cc(C)c(-c2cc(N)nc(C)n2)cc1C(C)C +C=CCN(Cc1ccc(OC)cc1)C(=O)NC1CC1 +CCC(C(=O)N1CCC(NC(=O)NCCOC)CC1)c1ccccc1 +COC(=O)c1cccc(NCc2nc(C(C)C)no2)c1 +COc1cccc(CNc2nc3[nH]c(C)cc(=O)n3n2)c1OC +CCNC(=O)CN(CC)C(=O)CNC(=O)C1CCCC1 +CC(C)C(=O)NCCN1CCN(C(=O)C(C)C)CC1 +Cc1cccc(N2Cc3nc(=O)n(CC(C)C)n3C2=O)c1 +CCOC(=O)C1CCCCN1Cc1c(F)cccc1F +CC(C)(C)c1cnc(CSc2ccncc2N)o1 +CC(CNC(=O)c1cc2ccccc2s1)CN1CCOCC1 +O=C(NCC1CCC1)c1cnc2sccn2c1=O +Nc1ccc(-c2cn3c(C(=O)N4CCOCC4)csc3n2)cc1 +O=C(Nc1ccc2ncccc2c1)c1csc(Nc2ncccn2)n1 +CC(C)c1nnc(Cn2nc(C(F)(F)F)ccc2=O)o1 +O=C(NC1CC1)N1CCCC(c2n[nH]c(C3CC3)n2)C1 +CCc1nccn1S(=O)(=O)c1ccc(Br)cc1OC +CC(C)(C)C(OC(=O)C1CCCN(C(N)=O)C1)C(F)(F)F +Cc1cnc(CNc2nc3ccccc3n3ccnc23)cn1 +CCn1nccc1C(=O)Nc1nc2c(SC)cccc2s1 +CC(C)Cc1nnc(NC(=O)c2ccncc2F)s1 +CN(C)c1ccc(C(=O)NCc2ccccn2)cc1 +CCOc1ccc(C(=O)N2CCN(CCO)CC2)cc1 +Cc1noc2ncc(NC(=O)c3cn(-c4ccccc4)nn3)cc12 +CC1CCCC(C)N1C(=O)CNc1cccc(OCC2CCCO2)c1 +Fc1cccc(CN2CCOC3C(OCc4ccccn4)CCC32)c1 +CC(O)CN1CCN(C(=O)c2cnnn2-c2ccccc2Cl)CC1 +Cc1cnc(C(=O)Nc2nnc(C(C)C)s2)cn1 +CC(C)OCc1ccc(CNC(=O)c2ccc(C#N)cc2)cc1 +CC(C)(C)CNC(=O)c1nccn1-c1ccccc1 +Cc1nn(C)c(C)c1CCNC(=O)Nc1ccc(F)c(Cl)c1 +Cc1nc(-c2cccc(C(=O)OCC(=O)Nc3cc(C)on3)c2)n[nH]1 +CCNC(=O)c1ccc(NC(=O)N2CCCC(C)C2)cc1 +CC(=O)c1ccc(NC(=O)c2ccc(Cl)cc2-n2cnnn2)cc1 +COC(=O)C(C)c1ccc(Nc2ccccn2)cc1 +CC(C)n1c(C2CCCN(Cc3n[nH]c(=O)[nH]3)C2)nc2ccccc21 +COc1ccc(C(O)CNC2=NS(=O)(=O)c3ccccc32)cc1 +CCN(CC)c1ccc(C(=O)N2CCCC(c3nc(C)no3)C2)cc1 +COc1cc(CNc2cnns2)ccc1Cl +CCC1CCCN(C(=O)C2CC(=O)N(c3ccc(OC)cc3)C2)C1 +O=C(CCCc1ccccc1)N1CCN(Cc2ccc(CO)o2)CC1 +CCOc1cccc(C(=O)NC2CCCc3ncncc32)c1 +Cc1cc(C)n2nc(C)c(C(=O)NCC(C)(C)N3CCOCC3)c2n1 +OCCOc1cc(F)ccc1NCc1noc2c1CCCC2 +CC(=O)c1[nH]c(C)c(C(=O)N(C)C2CCCc3ccccc32)c1C +CC(C)(C)NC(=O)c1cccc(Br)c1F +CCN(Cc1ccccc1)C(=O)CC1NCCc2ccccc21 +CCCCNC(=O)c1cccc(COc2ccc(C)nc2)c1 +Cn1nc(C(=O)NCc2cccs2)c(=O)c2ccccc21 +Cc1nc2cc(C3CCCC(=O)C3)ccc2n1C1CC1 +CC(=O)C(C)N1C(=O)C(C)Nc2cc3c(cc21)CCCC3 +CC1CCCCC1NC(=O)C1CC(=O)N(Cc2ccccc2)C1 +Cc1ocnc1CNC(=O)Nc1ccccc1N1CC(C)OC(C)C1 +N#Cc1cccnc1NCC(O)c1ccc(OC(F)(F)F)cc1 +COCCC1(CO)CCCN(c2ccc(Cl)cn2)C1 +Cc1cccc(NC(=O)c2c(C)c(N)c(C)[nH]c2=O)c1C +COc1ccccc1CN(C(=O)c1cccc2[nH]ccc12)C1CC1 +O=C(Nc1cccc2cccnc12)c1ccc(F)c(F)c1 +CNC(=O)c1ccc(NC(=O)c2ccc(C)nc2C)cc1Cl +CN(C)c1ccc(NC(=O)Cc2coc(-c3ccccc3)n2)cn1 +COc1ccc(Br)c2cc(C3(C)OCCO3)oc12 +NC(=O)CN(C(=O)Cc1ccc(Cl)c(Cl)c1)c1ccccc1 +O=C(NC(C1CC1)C1CC1)C1CC(=O)N(c2ccccc2)C1 +CC(=O)c1cccc(NC(=O)CSc2nccn2C)c1 +CC(C)(CNCc1ccc(Cl)c(Cl)c1)N1CCOCC1 +Cc1ccc2ncc(C(=O)Nc3cccc(F)c3C#N)n2c1 +CCN(C(=O)c1cccc(NS(C)(=O)=O)c1)c1ccc(F)cc1 +O=C(Nc1cc(N2CCOCC2)ncn1)c1ccccn1 +CC(=O)Nc1ccc(CN2CCOC(C#N)C2)cc1 +Cn1c(C(=O)NCCc2c[nH]c3ccccc23)cc2occc21 +CCc1nn2c(CO)c(-c3ccc4c(c3)ncn4C)nc2s1 +CC(C)(CO)NC(=O)c1csc(-c2cc3ccccc3[nH]2)n1 +CCc1cc2c(=O)n(CC(=O)Nc3ccc(C)c(C)c3)cnc2s1 +COCCOc1ccccc1NCc1ccsc1 +Cc1cccc(-n2nnc(C(=O)Nc3ccccc3)c2N)c1 +C=CCNC(=O)c1ccc(Oc2cccc(F)c2)o1 +CNC(=O)c1cccc(OC(=O)c2cc(=O)[nH]c3ccccc23)c1 +O=C(c1cc(C2CC2)n[nH]1)N1CC2CCC1CN(c1ncccn1)C2 +Cc1cnc(NC(=O)COc2cccc(F)c2)s1 +Cc1cc(=O)n2ncnc2n1CC1(O)CCC(C)CC1 +CN(C)S(=O)(=O)n1ccc(-c2ccccc2)n1 +CC1(CNC(=O)NCc2ccc3c(c2)OCCCO3)CCCC1 +CCCCN(Cc1ccccc1F)C(=O)C1CC(=O)N(C)C1 +CC(Cc1c(F)cccc1F)NC(=O)COc1ccccc1CO +Cc1cc(C(=O)NCCn2nc(C(F)(F)F)n(C)c2=O)no1 +CCc1ccc(C(=O)Nc2c(C)ccc(N)c2C)cc1 +COc1ccc(CCSc2nc(C)c(CCO)c(=O)[nH]2)cc1 +CC(C)OC(=O)c1ccc(OCC(=O)NC2CC2)cc1 +COCC(=O)NC(C(=O)Nc1nnc(C2CC2)s1)C(C)C +CC(=O)c1cccc(OCC(=O)C(C#N)c2nc3ccccc3[nH]2)c1 +O=C(CC1CCCCC1)N1CCN(CC(F)(F)F)CC1 +CC(C)NC(=O)Nc1ccc(-c2nc(C(C)C)no2)cc1 +CN(Cc1cccnc1)C(=O)NCc1ccc(OC(C)(C)C)nc1 +CCCCN(CC)C(=O)c1cnc2[nH]nc(C)c2c1 +Cc1nn(C)c(C)c1C(C)NC(=O)NCc1cccc2ccccc12 +CCc1nnc(CN(C)Cc2ccc(C(=O)OC)cc2)o1 +O=C1CC(c2ccc(F)cc2)Cc2nc3ncnn3cc21 +Cc1cccc(C)c1NC(=O)CCNC(=O)c1ccccc1 +O=C(c1ccc(-c2cc[nH]n2)cc1)N(Cc1cocn1)Cc1cocn1 +O=C(NCC1CC(=O)N(c2ccccc2)C1)NC1CCCCC1 +OC(COc1cccc2[nH]ccc12)Cn1nnnc1-c1ccccn1 +CCOc1c(O)c(Br)cc2c1C(C)NCC2 +NC(=O)Cc1ccccc1NC(=O)COc1ccc(F)cc1 +CC(OCC1CCCO1)C(=O)N1CCC(Nc2cccnn2)CC1 +O=c1[nH]nc(-c2cc(F)ccc2F)c2ccccc12 +C=CCNC(=O)Nc1cc2c(cc1SC)OCCO2 +Cc1ccc(F)c(S(=O)(=O)NCc2noc(C(C)(C)C)n2)c1 +C1=CCC(c2nccn2Cc2ccccc2-n2ccnc2)CC1 +Cc1ccc(C)c(S(=O)(=O)NC(C)(C)c2nc(C)c(C)s2)c1 +Cc1cc(C)n(C2CCN(C(=O)CCCc3cccs3)C2)n1 +Nc1cc(C(O)CN2CCOCC2)ccc1Cl +CCc1cc(-c2c(CCOC)noc2N)ccc1OC +COc1ccc(F)cc1NC(=O)CN(C)c1ncnc2[nH]cnc12 +O=C(CCS(=O)(=O)c1ccccc1)NCCn1ncccc1=O +CC(C)(CNC(=O)c1cccs1)c1ccncc1 +CC1CCCCN1S(=O)(=O)NCCc1c[nH]c2ccc(F)cc12 +O=C(CCn1ccc2ccccc21)OCCN1CCOC1=O +CC(C)n1c(SCc2n[nH]c(=O)[nH]2)nc2ccccc21 +OCc1nnn(Cc2cccc(F)c2)c1-c1cccnc1 +CN(C)C(=O)c1ccccc1NC(=O)Cc1cccc(OCC#N)c1 +CCC(CC)CNC(=O)C(N)c1cccc(OC)c1 +Cc1ncc(CNC(=O)NC(C)c2ccc(F)cc2Cl)s1 +CC(C)NC(=O)Cn1cnc2c(sc3cccc(Cl)c32)c1=O +O=C(Cc1ccccc1)NCc1ccc(N2CCCC2=O)cc1 +CCCNC(=O)CNC(=O)c1ccc(OC)c(Br)c1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)c1cc(Cl)c[nH]1 +CC(=O)N1CCCN(C(=O)CC2CCc3ccccc32)CC1 +O=C1CCN(C(=O)c2ccc3c(c2)NC(=O)CCO3)CC1 +Cc1cc(F)ccc1CCNC(=O)c1sccc1C#N +O=C(NCc1cscn1)c1cc(Cl)c2c(c1)OCCO2 +CCc1ocnc1C(=O)N(C)CC1Cc2ccccc2CN1C +COc1cc(CNC(=O)Nc2ccncc2)ccc1O +O=C(Cc1cccs1)NCCc1cccc(F)c1 +Cc1cccc(CN(C(=O)c2cnn(-c3ccccn3)c2C)C2CC2)c1 +Cc1ccc(C(O)C(=O)Nc2c(C)cccc2C)cc1 +N#Cc1ccc(NCc2ccncc2Cl)cc1C#N +Cc1c(C(=O)N2CCCC2c2ccncc2)sc2ccc(F)cc12 +CCCOc1cccc(-c2ncc(C(N)=O)c(N)n2)c1 +Cc1n[nH]c(C)c1S(=O)(=O)N(CCCO)C1CC1 +COc1ccc(C(=O)N(C)CC(O)C2CC2)cc1OC(F)F +O=C(Nc1ccccc1O)c1c(O)cc(F)cc1F +COc1cccc(C(=O)Nc2nc(C)c(C(C)=O)s2)c1 +Cc1cc(C(=O)NC2CCCc3[nH]c(=O)ccc32)c2c(C)noc2n1 +COc1ccc(OC)c(C(=O)N=c2sccn2C)c1 +CC1CC1NC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +CC(Sc1ccccc1)C(=O)NCCCN1CCCC1=O +CCCN(CC)c1ccc(C(=O)Nc2c(C)noc2CC)cn1 +CC1CN(C(=O)C2(C#N)CCC2)CC1N1CCOCC1 +C#CCNC(=O)CSc1nnc(-c2ccccc2OC)n1N +CCOc1ccc(-c2nc(NC(=O)c3ccncc3)sc2C)cc1 +O=C1CCC2(CCOC2)CN1Cc1csc(-c2cnccn2)n1 +Cc1cccc(OCCCNC(=O)Cn2nnnc2C)c1 +NC(=O)COc1ccc(CNc2cccc(F)c2)cc1 +Cc1cc(C)c(CN2C(=O)Cc3cc(N)ccc32)c(C)c1 +CCc1nnc(NC(=O)c2csc(-c3ccccc3)n2)s1 +CC(C)(C)c1noc(-c2cc(Br)c[nH]2)n1 +COCc1nc(Cc2cccc(Cl)c2)sc1C#N +O=C(Nc1ccc(F)c(F)c1F)C1CN(C(=O)c2cccs2)C1 +CN1C(=O)C2(CCN(C(=O)c3ccco3)CC2)c2ccccc21 +O=C(Nc1ccc(SCc2cccnc2)nn1)c1ccccc1 +COc1cccc(OC)c1C(=O)Nc1nnc(C2CCCCC2)s1 +COC(=O)COc1ccc(S(=O)(=O)N2CCCCC2)cc1Cl +COCCCNC(=O)CCc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +CCOc1ccc(C(=O)N2CCC(NS(C)(=O)=O)CC2)cc1 +CCc1ccccc1NC(=O)COc1nnc2ccccn12 +Cc1ccc(NC(=O)C2CCCN2c2nc3ccccc3o2)nc1 +Cc1ccc(-c2ncco2)cc1NC(=O)NCc1ncc[nH]1 +COc1ccc(C(CC(=O)OC2CCCC2)NC(C)=O)cc1 +COc1cc(OC)c(NC(=O)NC(C)C)cc1F +COc1ccc(SC(C)C(=O)NCc2ccccc2CO)cc1 +CN(C)C(=O)C1(CNC(=O)Nc2ccccc2)CCCC1 +Cc1ccc(Cl)c(OC(=O)c2sccc2-n2cnnn2)c1 +CC(C)COC(=O)N1CCN(Cc2cccc3cn[nH]c23)CC1 +CN(CC1COc2ccccc2O1)C(=O)NCc1cccs1 +Cn1c(=O)c2c(ncn2CCOC(=O)C2CC=CC2)n(C)c1=O +Cc1ccnc(CC(C)N(C)Cc2ccc(S(C)(=O)=O)cc2)c1 +COc1ccc(CN2CCCc3c(c(=O)n(C)n3C)C2)cc1 +NC(=O)C1Cc2ccccc2CN1Cc1cnn(-c2ccccc2)n1 +Cc1nc(N(C)C)sc1-c1csc(NC(C)C)n1 +CN1CC2(CCCN(C(=O)c3ccn(C(C)(C)C)c3)C2)OC1=O +N#Cc1ccc(C2NCCc3cc4[nH]ccc4cc32)cc1 +O=C1CCN(CCOc2c(Cl)cccc2Cl)CC1 +COc1ccccc1NC(=O)NCc1nc(-c2ccccc2)no1 +Cn1c(SCc2nccn2C(F)F)nnc1N1CCOCC1 +Cc1ccc(-c2ncco2)cc1NC(=O)Cc1cccnc1 +FC(F)(F)COCCNc1cccc(Cl)c1N1CCOCC1 +COC(=O)c1cc(S(=O)(=O)N(C)C)c(C)s1 +O=C(COc1ccc(F)c(F)c1)N1CCc2ccccc21 +O=C(CC12CC3CC(CC(O)(C3)C1)C2)Nc1ccccc1O +Nc1nc2c(ncn2CCC(O)CCO)c(=O)[nH]1 +Cc1ccc(C)c(NC(=O)c2cn3c4c(cccc4c2=O)CC3C)c1 +CC(C)N1CCCC2(CCN(C(=O)c3ccc(=O)n(C)c3)C2)C1=O +Cn1ccc(NC(=O)CCN2C(=O)COc3ccccc32)n1 +Cc1ccc(F)c(NC(=O)c2cccc(C#N)c2)c1 +CC(C)(C)C(=O)N1CCN(C(=O)Cn2c(=O)[nH]c3ccccc32)CC1 +CN(C)S(=O)(=O)Oc1cccc(F)c1OS(=O)(=O)N(C)C +C=CCSc1nc(=O)c2c(n1C)NC(=O)CC2c1cccc(C)c1 +O=C(Cn1c(=O)oc2ccccc21)N1CCNCC1 +Cc1nc2cc(-c3ccccc3)nn2c(C)c1CC(=O)N1CCCCC1 +Nc1nc(-c2ccccn2)ncc1C(=O)NC1CC1 +CC(=O)c1sc(NC(=O)C2CCCO2)nc1-c1ccccc1 +CCN(CCO)C(=O)NCCS(=O)(=O)c1ccccc1 +Cc1ncccc1NC(=O)Cc1ccc(F)c(F)c1 +COCCC1CCN(C(=O)c2ccc(F)cc2)CC1 +N#CCOc1cccc(CC(=O)NC2CCCC(C(F)(F)F)C2)c1 +Cc1occc1SCc1nc(C)c2ccccc2n1 +CCC(C)(C)NC(=O)COc1ccc(C(=O)OC)cc1 +CC(C)CCOc1cccc(NC(=O)Cn2cnnn2)c1 +Cc1cc2cc3c(cc2n2c(=O)n(Cc4ccccn4)nc12)OCO3 +CN(CCc1ccccn1)C(=O)NC1CCCCC1 +CCC(CCO)NC(=O)Nc1cccc(SC(F)F)c1 +COc1ccc(-c2ccc(SCC(=O)N(C)C)nn2)cc1OC +Cc1nnc(SCC(=O)Nc2nnc(SC(C)C)s2)n1N +CCCn1c(C)cc(C(=O)CN2CCC(=O)Nc3ccccc32)c1C +CC(NC(=O)C1CCN(S(=O)(=O)N(C)C)CC1)c1ccccc1 +Cc1nc(C)c(CNc2nccc(CCC(F)(F)F)n2)s1 +CC(=O)NC1CCCN(C(=O)Nc2ccc3ccccc3c2)C1 +CN(Cc1cccc(F)c1)C(=O)c1cc(C(N)=O)cs1 +Cc1ccc(NC(=O)CNC(=O)c2cc3sccc3n2C)cc1C +O=C(CC1NC(=O)c2ccccc2N=C1O)N=c1[nH]c2ccccc2[nH]1 +Cc1cc(C)c(S(=O)(=O)n2nc(C)c(C)c2C)c(C)c1 +CC(C)OCCC(=O)NC(C)(C#N)C1CCCCC1 +COc1ccc(N2C(C)=NS(=O)(=O)c3cccnc32)cc1Cl +Cc1cnc2c(c1)nc(Cc1ccc(F)cc1)n2CCO +Cc1ccc(C(=O)CCC(=O)N(C)Cc2ccc(F)cc2)s1 +CCNC(=O)c1cccc(CNC(=O)N2CCOCC2)c1 +Cc1ccnc2nc(C(=O)N(C)c3nccs3)nn12 +CCOC(=O)c1c(C)[nH]c2cc(Br)c(OC(C)=O)cc12 +Cc1ccc(F)c(NC(=O)CCN2C(=O)COc3ccccc32)c1 +COc1ccc(-c2nc3c(cnn3Cc3ccc(C)o3)[nH]2)cc1F +COc1ccc(NC(=O)Cn2cnc3onc(C)c3c2=O)c(OC)c1 +CCc1nc(C)sc1Cn1ccnc1-c1ccoc1 +CC(C)C1CN(C(=O)CCn2cnnc2)CCC(=O)N1CC1CC1 +COc1ccc(C(=O)OCC(=O)N2CCc3ccccc3C2)cc1 +Cc1cc(C(=O)N2CCN(CCNC(=O)c3ccncc3)CC2)no1 +CCCOC(=O)C1=C(C)Nc2nnnn2C1c1ccccn1 +CC(=O)Nc1cccc(-n2nnc(SCC(N)=O)n2)c1 +Cn1cc(C(=O)N2CCCC3CCCCC32)c(-c2cccs2)n1 +Nc1nncc(-c2ccncc2)c1C(=O)Nc1ccccc1F +COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccncc2)c1 +COc1ccc(-c2c(C(C)=O)c(C)nc3sc(C#N)c(N)c23)cc1 +COc1cccc(OC)c1COC(=O)c1cn(-c2ccccc2)nn1 +COc1ccccc1C(=O)NCC(=O)Nc1cc(F)ccc1C +O=C1CCCN1c1cccc(-c2csc(-c3ccco3)n2)c1 +COCc1cccc(C(=O)Nc2cccc(-n3cnnn3)c2)c1 +CCCCS(=O)(=O)NCC(=O)N1CCOc2ccccc21 +COc1ccc2occ(CC(=O)Nc3nnc(C(C)C)s3)c2c1 +Cc1ccc(C)n1NC(=O)COc1cccc(Cl)c1 +Cc1ccc(NC(=O)c2ccc3[nH]c(C)nc3c2)cc1 +CC(=O)c1csc(NC(=O)COc2ccc(C#N)cc2)n1 +NC(=O)c1ccccc1Oc1ccc(NC(=O)Cc2ccoc2)cc1 +Cc1ccc(NC(=O)CCNC(=O)OC(C)(C)C)c(Cl)c1 +CCc1ccc(C2COCCN2Cc2cnc(C(C)C)s2)o1 +CC(CC(=O)NC(C)c1ccc(S(N)(=O)=O)cc1)c1ccccc1 +c1cc(-c2nnc(NCc3nc4c(s3)CCC4)o2)ccn1 +CN(CC(=O)NC(C(N)=O)C(C)(C)C)C(=O)c1cccs1 +CC(C)(C)C(O)CNc1ccc(S(=O)(=O)N2CCCCC2)cn1 +CCOc1ccc2nc(SCC(=O)N3CC(C)OC(C)C3)[nH]c2c1 +CCOC(=O)C1CCC(NC(=O)Nc2ccc3c(c2)COC3)C1 +Cc1nn(CCNC(=O)C2COc3ccccc3C2)c(C)c1C +O=C(Nc1ccc(-c2ccccc2)cc1)c1ccccn1 +C=CCNC(=O)c1ccc(OCC(=O)N2CCCC2)c(N)c1 +Cc1ccn2c(=O)c(C(=O)Nc3ccnn3C(C)C)cnc2c1 +O=C(NCCc1cn2ccccc2n1)Nc1ccc(OC(F)F)cc1 +CC(C)c1nc2sc(-c3ccco3)nn2c1CO +Cc1cc(C)nc(SC2=NS(=O)(=O)c3ccccc32)n1 +O=C(CCn1cccn1)Nc1ccnn1C1CCCCC1 +CCOC(=O)c1sc(NC(=O)COc2ccc(C)cc2)nc1C +CC(NS(=O)(=O)c1ccccc1)C(=O)NC(C#N)C(C)(C)C +CC(C)c1c(C(=O)OCC=Cc2ccccc2)cnc2ncnn12 +Cc1cc(C(F)(F)F)c(C#N)c(SCC(=O)N(C)C)n1 +CC(C)CC1COCCN1C(=O)CSc1ccccc1 +O=C(Cc1ccc2c(c1)CCCC2)N1CCN(Cc2ccncc2)CC1 +NC(=O)c1cc(NC(=O)CCC(=O)c2ccccc2)cc(C(N)=O)c1 +COc1ccccc1CNC(=O)c1cc(C(N)=O)cs1 +O=c1[nH]c2ccc(Cl)cc2c(=O)n1CCCN1CCOCC1 +CC(=O)NCCCC(=O)N(Cc1c(C)nn(C)c1C)C(C)C +CCCCNC(=O)NCCc1ccc(-c2csc(C)n2)s1 +O=C(Nc1ccc2c3c(cccc13)CC2)c1nc[nH]n1 +Cc1noc(COCC(=O)N2CCCC2c2noc(C(C)C)n2)n1 +COc1ccccc1-c1nnc2n1NC1CCCC1S2 +CS(=O)c1ccc(NC(=O)c2ccnc(-n3ccnc3)c2)cc1F +COCCN1CCN(C(=O)NC(C)Cc2cc(C)cc(C)c2)CC1=O +O=C(C1CCN(CC(F)(F)F)CC1)N1CCCC1Cn1cccn1 +O=C(NC1CC1)C(Nc1cccc2c1OCCO2)c1ccccc1 +CCN(CC)C(=O)CCC(=O)NCc1oc2ccccc2c1C +CCOC(=O)C(C)NC(=O)Nc1ccc(C)cc1 +Cn1cnc(CNC(=O)N2CCCC2c2nc3ccccc3s2)n1 +CCc1c(C(=O)NCc2ccco2)cnn1-c1ccc(C)cc1 +Cc1ccc(F)c(NC(=O)c2ccc3ccccc3n2)c1 +COc1cc2cc(C(=O)NCCc3ccccc3)[nH]c2cc1OC +CCOCCNC(=O)C(C)Oc1ccc(Cl)cc1Cl +CC(=O)c1ccccc1NCC(=O)NCC1(c2ccccc2)CC1 +O=C(N1CCC(c2nnc3ccccn23)CC1)C1(c2ccccc2)CC1 +Cc1ncccc1C(=O)NC(C)(CNC(=O)OC(C)(C)C)C(C)C +Cc1n[nH]c(-c2nn3c(-c4ccccn4)nnc3s2)c1Cl +CNc1nccc(N2CCC(CC(=O)N3CCCCC3)CC2)n1 +Cc1noc(CCNC(=O)c2cccc(OCC(F)F)n2)n1 +CC(NC(=O)CCC(=O)c1ccc(F)cc1F)C(N)=O +COCCCNC(=O)C(C)Sc1ccc(Br)cc1N +COc1ccc(NC(=O)c2cc(=O)c3cc(N)ccc3o2)cc1 +Cc1cccc2c1CNCC2NC(=O)c1ccccn1 +COc1ccc(OC)c(S(=O)(=O)Oc2ccc3c(c2)CCC3)c1 +CC(C)CNC(=O)C1(NCc2cc(=O)c(O)co2)CCCC1 +CCN(Cc1cnc2ccccn12)C(=O)COc1ccc(OC)cc1 +Cc1occc1C(=O)OCC(=O)Nc1ccc(OC(F)(F)F)cc1 +CCc1noc(CC)c1CC(=O)Nc1nc(-c2ccsc2)ns1 +Cc1nonc1OCCNC(=O)CC1CCc2ccccc21 +Cc1cnc2n(c1=O)CC(C(=O)NCCc1ccccc1)CS2 +CC(C)C(=O)Nc1ccc(-c2ccc(S(C)(=O)=O)nn2)cc1 +Cc1ccc(C(=O)NCC(=O)NCCCc2ccc(O)cc2)s1 +N#Cc1c(N)cc(N)nc1SCCn1nc2ccccn2c1=O +COC(=O)c1cccc(NC(=O)C(C)n2c(=O)oc3ccccc32)c1 +CC1CCCC(C)N1C(=O)CN(Cc1ccccc1)CC(F)F +CCN(Cc1ccccc1Cl)C(=O)NC(C)COC +COCCOc1ncccc1NC(=O)c1ccccc1C(F)(F)F +COc1ccc(C(=O)N2CCN(C(=O)CN3CCOC3=O)CC2)cc1 +Cc1ccsc1CNC(=O)CCc1ccc(C#N)cc1 +Cc1cccc(-n2cc(C(=O)n3ccnc3)cn2)c1 +Cc1cc2oc(=O)cc(COC(=O)c3nccnc3N)c2cc1Cl +Cc1ccccc1C(NCC(=O)NC1CCCCNC1=O)C(C)C +O=C1CC(c2ccc(CO)o2)c2cnn(Cc3ccco3)c2N1 +CC(C1CC1)N(C(=O)COc1cccc(C#N)c1)C1CC1 +CC(C)C(=O)N1CCN(Cc2nc(C(F)(F)F)cs2)CC1 +Nc1c(OC2CCCCC2)ncnc1-n1ccnc1 +COCCN(CC(=O)N(C)C)C(=O)c1c(C)oc2ccc(OC)cc12 +CC(=O)Nc1ccc(CNC(=O)Cc2ccc3ccccc3c2)cc1 +CCn1nc(C)cc1C(=O)Nc1ccc(C(C)=O)cc1 +CCS(=O)(=O)N1CCC(NC(=O)CC(C)c2ccccc2)CC1 +CCNC(=O)c1ccc(-c2cc(Cl)ccc2C)nc1N +CN(Cc1nc2ccccc2s1)CC(C#N)CCC#N +Cc1noc(-c2ccccc2)c1NC(=O)c1cnccn1 +CCOc1cc(CNc2ccc(F)c(F)c2)ccc1OC +CCc1ncc(C(=O)NCc2cccc(Cl)c2)c(C)n1 +O=C(c1ccsc1)N1CCN(CCOCC2CCCO2)CC1 +CCOc1cc(C)c(C(O)CCCCO)cc1C +CCN(C(=O)C1CN(Cc2ccccc2)CCO1)c1nc(C)cs1 +CCSc1ccccc1OCC(=O)NCC(F)(F)F +O=C(COC(=O)Cc1cccs1)Nc1ncc(Cl)cc1Cl +O=C(NCc1cccs1)NCC1(c2ccc(F)cc2)CC1 +Cn1ncc2c(Nc3ccc(C(N)=O)cc3)ncnc21 +CC(C(=O)NC1CCCCC1)S(=O)(=O)c1nc2ccccc2[nH]1 +Cc1cc(C(=O)N(Cc2ccoc2)Cc2cccs2)c(C)o1 +CCOc1ccc(C(=O)C2CCN(S(C)(=O)=O)CC2)cc1 +CCCNC(=O)COc1ccccc1-c1nnco1 +COc1cc(C(C)O)ccc1OC1CCCC1O +CC1COCCN1C(=O)CCc1ncc(-c2ccc(F)cc2F)o1 +Cc1cc2occ(CC(=O)OCC(=O)NC(C)(C)C)c2cc1C +CCNC(=O)c1ccc(C)c(NC(=O)CCC(C)(C)C)c1 +Cn1ncc2c(=O)[nH]c(CN3CCCC3c3ccsc3)nc21 +O=C(Nc1ccsc1C(=O)NCC1CCCO1)c1cnccn1 +CC(=O)c1ccc2c(c1)N(CC(=O)Nc1ccccc1)C(=O)CO2 +CNS(=O)(=O)c1ccc(S(=O)(=O)NCCC(C)C)cc1 +Cc1noc(-c2ccc(S(=O)(=O)N3CCCCC3)s2)c1C +COc1cc(OC)cc(C(=O)Nc2cc(F)ccc2OC)c1 +COc1cc(C(=O)Nc2nnc(C3CCC3)s2)cc(OC)c1OC +COc1cc2c(c(OC)c1OC)-c1ccc(OC)c(=O)cc1CCC2 +Cc1nnnn1-c1ccccc1C(=O)N1CCc2ccccc2C1 +CCOC(=O)c1cnn(C)c1NC(=O)c1noc2c1CCCC2 +CS(=O)(=O)c1cccc(C2CNC(=O)CN2)c1 +CS(=O)(=O)N1CCN(C(=O)Nc2ccc(F)c(F)c2)CC1 +COCCNc1c(C)c(C)nc2cc(-c3ccco3)nn12 +CC1CCCC(NC(=O)COC(=O)Cc2cn3ccsc3n2)C1C +O=C(C1CCOCC1)N1CC2COCC2(COCC2CC2)C1 +CC(=O)c1nnn(C(C)C(=O)Nc2ccc(Cl)cc2)c1C +CC(C)N(Cc1cccc(C#N)c1)CC(F)(F)F +CCOC(=O)C=C(NCc1ccco1)C(F)(F)F +Cc1n[nH]c(=O)c(C(=O)Nc2cc(F)cc(N3CCCC3)c2)c1C +CCOCC(=O)NCc1ccc(C)cc1N(C)C +CCS(=O)(=O)N1CCN(Cc2cc(C)nc3ccccc23)CC1 +Cc1noc(COC(=O)c2cc(Cl)ccc2Cl)n1 +CCOc1cc(C)c(Cl)cc1S(=O)(=O)NC(CC)CO +CC(C)S(=O)(=O)c1ccc(C(C)(C)CO)cc1 +CC(NC(=O)NCCc1ccccc1)c1ccccn1 +CCCOc1ccccc1-c1ccc(CC#N)c(=O)n1C +COC(=O)C(C)NC(=O)CCc1nc2ccccc2[nH]c1=O +C=CCNC(=O)Nc1cccc(OC(F)F)c1C +CCN(C(=O)c1cc(N)nc2ccccc12)C1CC1 +CNC(=O)CSc1nnc(Nc2ccccc2C)s1 +CC(c1ccccn1)N(C)c1nc(N)nc2nc[nH]c12 +Cc1cc(CSc2ccc3ccccc3n2)no1 +COc1cccc(OC(C)CNCC(F)(F)F)c1 +CC(=O)NCCC(=O)N1CCC2C(CCC(=O)N2CCCO)C1 +N#Cc1cc(F)ccc1CSc1nnc(NC2CC2)s1 +CSc1ncc(C(=O)N(C)CCC#N)n1-c1ccc(F)cc1 +O=C(CCC1CCCC1)Nn1cnc2ccc(Cl)cc2c1=O +COc1cccc(OC)c1C(=O)Nc1ccccc1N1CCOCC1 +CC(Sc1nnc(C2CC2)n1C)C(=O)c1c[nH]c2ccccc12 +CCOCC(=O)NCCc1csc(-n2cccn2)n1 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1ccc(=O)oc1 +CCOc1cccc(CNc2cc(C)nc(C)n2)c1 +C(=Cc1ccco1)CNc1ccc(-c2nnco2)cc1 +COc1cc(NC(=O)c2cc(C)on2)cc(OC)c1 +Cc1nn(C)cc1C(=O)OCC1CC(=O)N(C2CC2)C1 +Cc1nccc(CNS(=O)(=O)c2cn[nH]c2)n1 +O=C(c1cccc(OCC(F)F)n1)N1CCc2sccc2C1 +Cc1ccccc1SCc1nc(N)nc(N(C)C)n1 +CSc1ccc(Cl)cc1NC(=O)NCCCOC(C)C +Nc1ccc2c(C(=O)Nc3cc(F)ccc3F)nccc2c1 +CCOCC1CCCN(C(=O)c2csc(-c3ncccn3)n2)C1 +CCN1CC(C(=O)NCc2nc(-c3ccncc3)no2)CC1=O +c1cc(C2NCCc3ccc4c(c32)OCCO4)ccn1 +CCc1ccc2c(c1)nc(CO)n2Cc1cccc(C#N)c1 +CC(CCCO)NC(=O)Nc1ccc(-c2nnnn2C2CC2)cc1 +COCCOc1cccc(CNC(=O)Nc2ccc3c(c2)COC3)c1 +CCc1ccccc1N1CC(C(=O)NC2CCCC(C)C2)CC1=O +Cc1occc1CN(C)C(=O)CCCc1cc(F)ccc1F +COC(=O)Cn1cc(NS(=O)(=O)c2ccccc2)cn1 +CC(O)c1cc(-c2ccc(C(F)(F)F)cc2)no1 +CCn1c(=O)[nH]c2cc(C(=O)OC3CCCCC3OC)ccc2c1=O +CN(Cc1ncnn1C)C(=O)c1cn(C)nc1C(C)(C)C +CCN(CC)C(=O)Cn1cnc2c(nnn2-c2ccccc2)c1=O +CCC(=O)N1CCN(c2nc(C)nc3sc(C)c(C)c23)CC1 +Cc1cn[nH]c1C1(C)CCN(c2cnccn2)CC1 +CCCn1cc(N)cc1C(=O)NC(C)C(=O)NC +C#CCOc1cccc(NC(=O)C(C)c2ccsc2)c1 +CC(=O)Nc1ccc(S(=O)(=O)NC(C)C(N)=O)cc1 +C=CCc1ccccc1OCC(=O)Nc1ccc2c(c1)OCO2 +Cc1ccncc1NC(=O)Nc1ccc(CN2CCOC2=O)cc1 +CCSc1ccccc1C(=O)Nc1cc(N2CCCCC2)ncn1 +CCOC(=O)c1nnc2c(C(=O)OCC)ncn2c1N +CC(CC(O)c1ccccc1)NC(=O)C1(O)CCCC1 +COc1cccc(C(=O)c2c[nH]c(C(=O)NCc3cccnc3)c2)c1 +Cc1ccncc1NC(=O)N1CCN(c2cnccn2)CC1 +NC(=O)c1cccc(NC(=O)CCSc2ccc(F)c(F)c2)c1 +O=C(c1cn[nH]n1)N1CCN(CC=Cc2ccccc2)CC1 +CCOc1ccc(C(=O)N(C)CC(O)COC)cc1 +CCc1cccc(C)c1NC(=O)c1ccc2c(c1)OCO2 +Cc1cc(=O)n(CC(=O)NCc2ccc(F)cc2F)c(N)n1 +Cc1nc(C2CCCCCN2C(=O)c2cc(C(C)C)[nH]n2)no1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)CC1CC2CCC1C2 +CC(C)OC(=O)CSc1nnc(-c2ccccc2O)n1N +Cc1cccc(C(=O)OCC(=O)Nc2ccc3c(c2)OCCO3)c1O +CCN1C(=O)C(C)(C(=O)NC2CCCCCC2)Oc2cccnc21 +O=C(c1cnn2ccccc12)N1CCN(C(=O)C2CC2)CC1 +Cc1ccc(CNC(=O)NCc2nnc3n2CCCC3)s1 +Cc1nc(C)c(CC(=O)N2CCN(c3ccc(F)cc3)CC2)c(=O)[nH]1 +Cc1nn(C)c(C)c1CC(=O)NC(C)c1ccc2c(c1)OCO2 +O=C(Nc1nnc(-c2ccncc2)o1)c1ccc(Br)cc1 +C#CCCOC(=O)c1[nH]nc(C2CC2)c1Br +COCCCNC(=O)c1cc(C2CC2)nn1-c1ccccc1 +CCCCN(Cc1ccccc1F)C(=O)c1nc2nccc(C)n2n1 +CN(Cc1ccc(F)cc1)C(=O)NCc1ccc(-n2cncn2)cc1 +O=C(NCC1CCN(C(=O)c2ccoc2)CC1)Nc1ccc(F)cc1 +O=S(=O)(NCCc1ccc(F)cc1)c1ccc(F)c(F)c1F +CCS(=O)(=O)c1ccc(NC(=O)COc2cc(C)on2)cc1 +CCNC(=O)CNC(=O)Cc1coc(-c2ccccc2)n1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3c(F)cccc3Cl)cc12 +CN(C)C(=O)c1nnn(-c2ccc(NC(=O)C3CC=CCC3)cc2)n1 +CNc1nc(-c2cc(-c3ccncc3)nn(C)c2=O)cs1 +COc1ccc(CCc2cc(C)nc(C)n2)cc1N +COC(=O)C(C)N1CCN(Cc2nccn2C(F)F)CC1 +Nc1ccc(=O)n(CC(=O)NCCC2CCCC2)c1 +O=C(OCCn1cnc2ccsc2c1=O)c1scnc1C1CC1 +N#CCn1ccnc1-c1cc(Cl)cc(Br)c1 +CC(C)COc1ccccc1NCc1noc(-c2ccoc2)n1 +O=C(OCC(=O)N1CCCC1)c1cc(Cl)ccc1Cl +COC(=O)c1sccc1OC(=O)c1cc2ccccc2oc1=O +N#Cc1ccc(CNC(=O)N2CCCC2C2CCC2)c(F)c1 +Cc1cc(C(=O)Nc2c3c(nn2-c2ccccc2)CCC3)no1 +CCCCN(C)C(=O)c1cc(N)n(-c2cccc(Cl)c2)n1 +Cc1cccc(-c2[nH]ncc2CN2CCN(C(C)C(N)=O)CC2)c1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cccc(OC(F)F)c3)cc12 +O=C(Cn1ccc2ncccc2c1=O)NCc1ccccc1 +O=C(NCc1nccn1C(F)F)c1cccc(OCC(F)F)n1 +N#CCCn1nc(-c2ccc(Br)cc2)cc1N +COC(=O)c1sc2c(cnc3ccc(Cl)cc32)c1N +Cc1cccc(C(=O)Nc2ccccc2-n2cnnn2)c1C +COCCNC(=O)c1ccc(Cl)c(NC(=O)c2ccsc2)c1 +CC(=O)Nc1ccc(NC(=O)c2ccco2)c(O)c1 +COc1ccc(C)cc1NC(=O)c1cn2cccnc2n1 +Nc1ccc2nc(NC(=O)CC(F)(F)F)sc2c1 +Cc1cc(Br)ccc1-n1nc(C)c(N)c1C +CC(NC(=O)N(C)Cc1ncnn1C)c1ccc(C(C)(C)C)cc1 +Cc1cc(C)n(CCC(=O)Nc2cc(Cl)cc(Cl)c2)n1 +CC(C)n1cnc(S(=O)(=O)N(C)c2ccc3ccccc3n2)c1 +Cc1ccc(C(=O)N(C)CCc2ccncc2)cc1N +Cn1cnc(CNC(=O)N(Cc2ccc(F)cc2F)C2CC2)n1 +CC(NC(=O)C1(c2ccc(F)cc2F)CCOCC1)C1CCOC1 +COc1ccccc1CC(=O)N1CCCN(c2nccc(C)n2)CC1 +O=C(Nc1cccc(Cn2cccnc2=O)c1)c1cc2ccccc2o1 +CCn1cc(C#N)c(=O)c2cc(C(F)(F)F)ccc21 +O=C(CSc1ccccc1)NCCCN1CCCCCC1=O +CC(CNC(=O)CSc1ccncc1)N1CCc2ccccc21 +O=C(Nc1c[nH]c2cc(Cl)ccc2c1=O)N1CCn2cnnc2C1 +OC(CNCc1cccnc1)c1ccc(C2CCCCC2)cc1 +Brc1cccc(CCc2ncncn2)c1 +O=C(c1cccc2ccccc12)N1Cc2cncnc2C1 +O=C1CCC(C(=O)Nc2ccc(F)c(Cl)c2)N1 +CC(NC(=O)C(C)S(=O)(=O)c1nccs1)c1ccc(F)cc1 +Cc1cc(NC(C)C(=O)N2CCCC2)ccc1F +COc1ccc(C)cc1C(C)C(C#N)N1CCCC1 +CCCn1cc2c3c(cccc31)CN(C(=O)c1ccccc1)CC2 +CCC(C)NS(=O)(=O)Cc1cccc(NC(=O)C(C)(C)C)c1 +CCCC(=O)Nc1ccc(Cl)c(NCc2nc(C)c(C)o2)c1 +O=C(Nc1ccccc1F)c1nnc2sccn12 +COc1ccc(C(C)(C)C)cc1S(=O)(=O)N1CCNCC1 +COc1ccc(-c2cc(-c3ccc(OC)c(O)c3)c(C#N)c(N)n2)cc1 +CC1(C(=O)NCc2cccs2)Sc2ccccc2NC1=O +CCCOc1cccc(C(=O)NC2CCN(c3ncccn3)CC2)c1 +O=S(=O)(Cc1ccccc1)NCC(O)c1ccc(Cl)cc1 +Cc1csc(C(C#N)C(=O)CCC2Cc3ccccc3NC2=O)n1 +O=C(N1CCOCC1)N1CC(n2cc(-c3ccccc3)nn2)C1 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1cnccn1 +CCOC(=O)c1cnn(-c2cccc(F)c2)c1F +COC(=O)c1sc(NC(=O)c2cccc(NC(C)=O)c2)cc1C +c1cnn(CC2CN(Cc3nnc(C4CC4)o3)CCO2)c1 +CC(C)(C)CC(=O)N1CCCC1C(=O)Oc1ccc2cn[nH]c2c1 +O=C(C1CCOCC1)N1CCn2c(Cn3cccn3)cnc2C1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)c2ccnnc2)c1 +COC(=O)C1CC1C(=O)N1CC(c2ccccc2C)CC1C +CC(C)NC(=O)N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1 +Cc1ccc(-c2nnco2)cc1NC(=O)NCC1(O)CCCCC1 +CCN(CC(C)C#N)C(=O)COc1ccc(C#N)cc1 +CCOc1cccc(CNC(=O)c2ccc3ncccc3c2)c1 +C=CCNC(=O)NCC1(c2cc(C)ccc2OC)CCOCC1 +Cc1ccc(S(=O)(=O)N(C)CCc2ccccc2)cc1 +CC(C)C(NC(N)=O)C(=O)NCc1ccc2c(c1)OCO2 +CC(C)(C)OC(=O)N1CCCC2(Cc3ccccc3NC2=O)C1 +O=C(CN1CCCc2cccc(F)c21)N1CCCCC1 +Cc1ncc(CNC(=O)c2cc(F)c(F)c(F)c2)s1 +O=C(NCCC(=O)N1CCC(Cc2ccccc2)C1)c1cccs1 +O=C(NCC(=O)c1ccco1)c1ccc(Cl)cn1 +N#CC(NC(=O)CNC(=O)c1cc(F)cc(F)c1)C1CCCCC1 +Cc1ccccc1COc1cccc2ccc(=O)[nH]c12 +COc1ccc2c(C)c(C(=O)NC3CCOCC3)oc2c1 +O=C(CC1CCCC1)N1CCCN(C(=O)Nc2nncs2)CC1 +CCC(CC)NC(=O)c1ccc(-n2nc(C)cc2C)cc1 +COc1ccc(NC(=O)C(C)Cc2ccccc2F)cc1NC(C)=O +CCOCc1cccc(NCc2ccc(-n3cncn3)c(C)c2)c1 +COCCNC(=O)c1ccc(NC(=O)C(C)OC)cc1Cl +Cc1noc(C2CC3OCCC3N(c3nnc(C)s3)C2)n1 +CC(=O)NCC(=O)NCC(=O)N(C)Cc1cscn1 +CN(C(=O)c1ccccc1Cl)C1(C#N)CCCCC1 +Cc1cccc(N2CCN(C(=O)C3CCC3)C(C)C2=O)c1C +CS(=O)(=O)c1ccc(-c2noc(CC(O)c3ccccc3)n2)cc1 +CCN1C(=O)C(O)(Cc2ccncc2)c2ccccc21 +O=C(NCc1ccco1)Nc1nnc(C2CC2)s1 +CN1CCN(Cc2cccnc2)C2(CCN(c3ncccn3)C2)C1=O +O=C(NC1CCCC1)c1ccc(NC(=O)N2CCCC2)cc1 +CC(C)CCOC(=O)c1cnn(C)c1-n1cccc1 +Cc1cc(=O)oc(C)c1C(=O)Nc1cccc(-c2cnco2)c1 +CC(=O)N(Cc1cccs1)c1ccc(F)cc1F +CC(CN1CCOCC1)OC(=O)c1cccn1C1CC1 +Cc1cc(C(=O)Nc2ccc(F)cc2)c2cnn(C(C)C)c2n1 +Cc1cc(C(C)NC(=O)N(C)C(C)c2cccc(O)c2)c(C)o1 +O=C(Cc1ccccc1F)NCCc1nc2ccccc2[nH]1 +O=C(Nc1nc[nH]n1)c1ccc(OCc2ccccc2)cc1 +CCCOC(=O)c1csc(-c2ccsc2)n1 +CCC(CC)(CO)NC(=O)c1c(F)cccc1Cl +O=C(NCc1cccc(-c2nccs2)c1)c1cccs1 +COc1ccc2ccn(CC(=O)NCC(F)(F)F)c(=O)c2c1 +Cn1c(=O)oc2cc(NS(=O)(=O)c3ccccc3)ccc21 +Cc1ccc(CNC(=O)NC2CCCCC2O)c(N(C)C)c1 +NC(=O)CCN1CCN(C(=O)C2CCCCC2)CC1 +O=C(Nc1ccc2ncccc2c1)C1COc2ccccc21 +O=C(CNC(=O)Nc1ccccc1-n1cccn1)NC1CC1 +O=C(Cc1ccc(F)cc1)N1CCOc2ccccc21 +Cc1occc1C(=O)N1CCN(c2cc(C#N)ccn2)CC1 +CCC(C)C(C)NC(=O)C1CC(=O)N(C(C)c2ccccc2)C1 +Cc1csc(SCC(=O)Nc2cc(C)nn2-c2ccccc2)n1 +O=C(NCCCNC(=O)c1ccc2[nH]cnc2c1)c1cccc(F)c1 +CCN(CC)S(=O)(=O)N1CCC(NC(=O)c2ccsc2)CC1 +COc1ccc(OC)c(NC(=O)c2cccc(C)c2N)c1 +Cn1nc(C(=O)NCCO)cc1NC(=O)CCc1ccccc1 +c1ccc2c(c1)CCN(Cc1ccc(-n3cncn3)cc1)CC2 +CC(C)OCCCNc1ncnc2ccc(Br)cc12 +CCC(=O)N1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1 +CC(NC(=O)c1ncc(-c2ccccn2)o1)c1ccccc1 +COc1cc(C(=O)N2CCc3ccccc32)cc(Br)c1O +O=C(CNc1ccc(NC(=O)C2CC2)cc1)Nc1cc(F)cc(F)c1 +Cc1cc(C(=O)Nc2ccccc2Cl)c(C)n1C1CC1 +Cc1cc(C(=O)NC2CCC3(CCC(=O)N3)CC2)no1 +N#Cc1ccc(Sc2nc(CCC3CCCC3)n[nH]2)nc1 +Cc1ccc(NCC(=O)NC2CCCCC2C)cc1-n1cnnn1 +CCN(CC)C(=O)CCC(=O)N1CCC(CC(N)=O)CC1 +CC(C)Oc1ccc(C(=O)Nc2c(C(N)=O)oc3ccccc23)cc1 +CC1(C)CCCN(C(=O)CCn2ccc3ccncc32)C1 +CC(=O)Nc1ccc(OCC(=O)NCCc2c(F)cccc2F)cc1 +O=C(CN1C(=O)CNc2ccccc21)NCC1CCCO1 +O=C(CNC(=O)Cc1ccc(Cl)cc1)NCc1ccco1 +Cc1noc(CCCNC(=O)N2CCC3(CCCCC3)CC2)n1 +CC(=O)N1CCCc2cc3c(cc21)N(C(C)=O)CCC3 +COc1ccc(C#CCNC(=O)Cc2ccccc2)cc1 +Cc1cc(CC(=O)N2CCC3(CCCN(CC4CC4)C3=O)C2)on1 +CCc1c(C)sc2nc(CC(=O)OCCOC)[nH]c(=O)c12 +CCCN(CC(=O)OCC)C(=O)c1cc(F)c(F)cc1Cl +CC(C)N(Cc1ccccc1)c1c(Cl)cn[nH]c1=O +COc1ccc(NC(=O)c2ccc(N)c(C)c2)cn1 +COCCNC(=O)COc1ccc(C(C)=O)cc1 +Cc1nc(C)c(-c2nnc(-c3ccc(Cl)cc3)o2)s1 +Cc1ccc(-c2nnco2)cc1NC(=O)C1COc2ccccc2O1 +O=C(COc1ccc(F)cc1)N1CCOC2C(OCC3CC3)CCC21 +C#CCNC(=O)N(Cc1ccc(O)cc1)CC1CC1 +O=C(COC(F)(F)F)c1ccccc1Br +C#Cc1cccc(N(Cc2ccccc2)C(=O)CCC=C)c1 +Cc1ccc(C(CN2CCOCC2)NC(=O)c2cnc(C)cn2)cc1 +CCc1ncc(C(=O)NCCNC(=O)OC(C)(C)C)s1 +COc1ccnc2c1c(=O)n(Cc1ccccc1)c(=O)n2C +Cn1cc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)nn1 +CNc1cncc(C2CCN(c3ncccn3)CC2)n1 +COc1ccccc1CC(=O)NCCS(N)(=O)=O +Cn1cc(-c2ncc[nH]2)c(-c2cccc(Cl)c2)n1 +CC(C)(C)c1ccc(S(=O)(=O)NC2(C(N)=O)CCCCC2)cc1 +Cc1cnn(CC2CCCCN2C(=O)COCCC(C)C)c1 +COc1ccc(OC(=O)c2ccnc(-n3ccnc3)c2)cc1F +CCCOC1CCCN(c2ccc(F)cc2CO)C1 +Cc1cnc(CNC(=O)Nc2ccc(OC(F)F)cc2)s1 +COc1ccc(SCCC(=O)Nc2c(C)cccc2C)cc1OC +O=C(Nc1ccc(-c2cn3ccsc3n2)cc1)c1ccc[nH]c1=O +O=C(NCc1ccco1)c1cc(-c2cccc(F)c2)ns1 +O=C(NCCn1cccn1)C1COC(=O)N1CC1CCCCC1 +O=C(NCc1ccc(Cl)cc1)C(c1ccccc1)n1cnnn1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)N1CCCC1C1CCCC1 +CCN1CCN(CCOc2c(C)cc(C)cc2Cl)C(=O)C1=O +CS(=O)(=O)c1nccn1Cc1coc(-c2cccs2)n1 +CCCC(=O)N1CCCC(C(=O)N2CCOCC2)C1 +Fc1cnc(N2CCCC(c3nncn3C3CC3)C2)nc1 +C#CCN1CCN(C(=O)CNC(=O)c2ccccc2OCC)CC1 +CC(C)C(C#N)OC(=O)c1ccc2nccnc2c1 +CCc1ccc(C(=O)N2CCCC(C(=O)Nc3ccccc3)C2)cc1 +O=C(CCCOc1ccccc1F)Nc1nc[nH]n1 +COC(=O)N(C)c1ccc(NC(=O)CCNC(=O)C(C)(C)C)cc1 +Cc1cccc(S(=O)Cc2ccc(C(=O)NC3CCCCC3)o2)c1 +CCC(CC)NC(=O)Cn1cc(C(F)(F)F)ccc1=O +O=C(Nc1cc(C(F)(F)F)ccc1F)c1ccncc1F +O=C(c1ccc(S(=O)(=O)c2ccccc2)s1)N1CCCCC1 +O=C(NCC(=O)N1CCCc2ccccc21)NC1CCC(O)CC1 +O=c1c2cnc3ncnn3c2ccn1Nc1ccccc1 +CC(=O)c1cc(F)cc(C(C)(O)C(F)(F)F)c1 +Cc1csc(=O)n1CCn1nc(-c2ccc(F)cc2)oc1=O +O=C(c1ccncc1)N1CCn2cccc2C1c1ccccc1 +Cc1n[nH]cc1NC(=O)c1oc2c(c1C)C(=O)CCC2 +O=C(NC1CCCC1)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +CNc1ccccc1C(=O)N1CCCN(C(=O)COC)CC1 +Cn1cccc(NC(=O)COc2cccc3c2OC(C)(C)C3)c1=O +Cc1ccc2c(c1)c1nnc(SCC(=O)N3CCCC3)nc1n2C +COc1ccc(S(=O)(=O)Oc2cccc3cccnc23)cc1 +O=C1CCSc2ccc(C(=O)NCC3CC3)cc2N1 +CN(C)C(=O)c1cccc(CNC(=O)C2CCOC2)c1 +Cn1ccnc1C(NC(=O)c1cc2ccccc2o1)c1ccccc1 +CC(C)N(Cc1ccccc1)C(=O)c1ccc(O)cc1 +O=C(CNC(=O)c1ccc2cc[nH]c2n1)NCc1ccccc1 +OC1CCC(Nc2ccc(CN3CCOCC3)cc2)CC1 +COc1cc(F)ccc1NC(=O)NCC1CCC1 +Cc1n[nH]c(C)c1C(=O)Nc1ccc(Br)cn1 +Cc1c(C(=O)N2CCCC2c2ccc(C(C)C)cc2)cnn1C +CCN(CC)C(=O)C(C)n1nc(-c2ccc(C)cc2)ccc1=O +CC1CC2CN(C(=O)CCOc3ccccc3)CCC2O1 +CC(C)c1ccc(S(=O)(=O)Cc2ccc(C(N)=O)cc2)cc1 +CNC(=O)c1cccc(COc2cccc(F)c2C#N)c1 +CC(C)=CC1C(C(=O)Nc2nncs2)C1(C)C +COCC(=O)Nc1cccc(NC(=O)CC2CCc3ccccc32)c1 +C=CCn1c(C)cc(-c2csc(NCC)n2)c1C +Cc1ccn(-c2ccc(NC(=O)Cc3ccccc3)cc2)n1 +CCN(CC)C(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1 +CN(CC(F)(F)F)C(=O)CN1CCN(c2ccccc2F)CC1 +COc1ccc(-n2cc(C(=O)NCc3cccs3)nn2)cc1 +CCOC(=O)c1[nH]nc(-c2ccccc2)c1Br +O=C(Nc1cc(F)ccc1F)c1cc2ccc3cccnc3c2[nH]1 +Cc1cc(NC(=O)c2cc(F)c(F)c(F)c2)ccc1C(=O)N(C)C +CCS(=O)(=O)NCC1CC(=O)N(Cc2ccc(F)cc2)C1 +C#CCOC(=O)CC(C)NC(=O)C1CCCCC1 +CCN(Cc1ccco1)S(=O)(=O)c1ccc(OC)c(F)c1 +COc1ccc2nc(NC(=O)c3c(C)cnn3C)sc2c1 +CNc1cccc(-c2nnc(N3CCCCC3)o2)c1 +O=C(Nc1ccc(-n2cc(Cl)cn2)cc1)c1ccccc1 +O=C(CCCn1cncn1)N1CCCN(c2ccc(F)cc2)CC1 +CCn1cnnc1CNC(=O)NCC1(c2ccccc2F)CC1 +CN(c1ccccc1)c1ncnc(Oc2ccccc2)c1N +COc1ccc(NC(=O)c2ncccn2)c(OC)c1 +COC(=O)CNC(=O)c1ccc(-c2ccccc2)o1 +CC(=O)c1ccccc1OCC(O)Cn1cnc2cc(C)c(C)cc21 +CCn1nnc2cc(C(=O)Nc3cc(Cl)ccc3OC)ccc21 +CCC(C)(C#N)NC(=O)CNC(=O)c1cc2c(s1)CCCC2 +COc1ccc(Cl)cc1NC(=O)c1onc(C#N)c1N +CCn1c(N2CCCC2)nc2c1c(=O)[nH]c(=O)n2C +O=C(c1ccnc(OC2CCC2)c1)N1CCSc2ncccc21 +Cc1cc(OCCSc2ncn[nH]2)ccc1C(C)C +COC(=O)c1ncc(Br)c2c(F)cc(F)cc12 +Cc1nn(C)c(C)c1NC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +C=CCNC(=O)c1ccc(NC(=O)NCCOC)cc1 +O=C(c1c[nH]nc1-c1cccc(Cl)c1)N1CCCS1(=O)=O +COC(=O)c1ccc(-c2nc(Cc3noc(C)n3)no2)cc1 +Cc1cccc(CNC(=O)c2cccc3ncccc23)c1 +CCOc1cc(S(=O)(=O)N2CCN(CCO)CC2)ccc1F +CCC(C)(C)NC(=O)C(C)Sc1ccc(N)cc1C +CN(C)C(=O)Sc1ccc(NC(=O)Cn2ccccc2=O)cc1 +CCn1cc(Br)cc1C(=O)Nc1ccc(=O)n(C)c1 +CCC(=O)N1CCCCC1c1nc(C)cc(Nc2nc(C)cs2)n1 +CC1CN(C(=O)CCNc2ccc3nnnn3n2)CC(C)O1 +Cc1ccc(C)c(OCC(=O)Nc2c(C)nn(C)c2C)c1 +O=C(Cn1cc(Br)c(=O)[nH]c1=O)Nc1ccncc1 +NC(=O)NCCCCC(=O)Nc1nnc(-c2ccsc2)s1 +CC(=O)N1CCN(C(=O)c2ccc3ccccc3c2)CC1 +Nc1ccc(F)c(NC(=O)COCC(F)(F)C(F)F)c1 +COc1cccc(CC(=O)NCc2nc3ccccc3s2)c1 +O=C(NCc1n[nH]c(=O)c2ccccc12)c1cc(-c2ccccc2)n[nH]1 +O=c1oc2ccccc2n1CCOc1ccccc1F +Cc1cc(NC(=O)c2ccc(=O)n(-c3ccccc3)c2)n(C)n1 +CC(NC(=O)c1ccccc1)C(=O)N1CCN(c2ncccn2)CC1 +COc1ccc(CNC(=O)CCC(=O)N2CCOCC2)cc1 +Cc1ccc(NC(=O)Nc2ccc3c(c2)oc(=O)n3C)cc1 +NC(=O)c1coc(-c2csc(N3CCCCCC3)n2)c1 +COc1cc(CNC(=O)CCC#N)cc(OC)c1OC +O=C1CCN(C(=O)CCSc2ccccn2)CCN1 +O=C(NCCCn1nc2ccccn2c1=O)c1ccc2ccccc2c1 +O=C(CCc1ccccc1F)NCc1cccs1 +CC(C)(C)NC(=O)c1nc2ncc(Br)cn2n1 +CCn1c(NCc2cnnn2C)nc2cc(Br)ccc21 +CC(C)c1nc(CCNC(=O)c2sccc2-n2cnnn2)cs1 +COC(CNC(=O)NC(C)C)c1ccccc1C +CCCCS(=O)(=O)N1CCC(c2nnc(C(C)C)o2)CC1 +CCC(CNC(=O)C1COCCO1)c1ccccc1 +COCc1cccc(CNC(=O)c2[nH]nc(C)c2Br)c1 +Cc1cc(C)c(CNC(=O)c2sccc2Br)c(=O)[nH]1 +CC(C)n1cc(S(=O)(=O)NCCc2ccccc2)cn1 +N#Cc1nc2cc(N)ccc2n1CCN1CCOCC1 +COc1ccc(SCC(=O)N2CCNCC2)cc1OC +Cc1cccc(OCC(C)NC(=O)Nc2nc(C)cs2)c1 +O=C(NCC1CC(=O)N(c2ccc3c(c2)OCO3)C1)c1ccccc1 +CCCCn1nccc1NC(=O)c1sc(C)nc1C +O=C(NCCc1c[nH]c2ccc(F)cc12)c1n[nH]c2c1CCCCC2 +O=C(Cc1ccc2c(c1)OCCO2)NC1CCCc2ccccc21 +COC(=O)N1CCc2nc(NC(=O)c3cc(C)n(C)n3)sc2C1 +O=C(CCSc1ccc(Br)cc1)Nc1cccnc1 +O=C(Cc1ccccc1)Nc1cn(-c2ccccc2)[nH]c1=O +CSc1sc(NC(=O)CCn2cncn2)nc1C +COCC(C)NC(=O)N(C)Cc1ccc(SC)cc1 +COCc1nc2ncc3c(=O)n(-c4cc(C)[nH]n4)ccc3n2n1 +COc1ccccc1Oc1ncccc1CNC(C)=O +NC(=O)CC(c1ccccc1Cl)C1CCCC1 +NC(=O)c1ccc(N2CCc3ccccc3C2)cc1 +CCCc1cc(C(=O)N(C)c2ccc(F)c(F)c2)[nH]n1 +Cc1ccc(OCC(=O)NC(CO)C(O)c2ccc(N)cc2)cc1 +CC(=O)c1ccc(NC(=O)c2cn3cc(Cl)ccc3n2)cc1 +CC(CNC(=O)c1cnn(C(C)(C)C)c1)Oc1ccccc1 +CCc1c(C)nc(SCC(=O)Nc2nccs2)[nH]c1=O +COc1cccc(C(=O)Nc2nn(C)c3c2CC(C)C(=O)N3)c1OC +COc1cccc(-c2cc(-c3ccc(C(=O)NC4CC4)cc3)[nH]n2)c1 +O=C(Cc1ccc(Cl)cc1Cl)Nc1ccon1 +CS(=O)(=O)N(Cc1cccnc1)c1ccc(Cl)cc1 +Cc1ccccc1C(=O)NCc1ccc(N2CCCCC2=O)cc1 +CNC(=O)c1cccc(NC(=O)C2(c3ccccc3)CCOCC2)c1 +Cc1cc(Br)ccc1S(=O)(=O)Nc1ccnn1C +Cn1nnc2c(NCCc3ccccc3)ncnc21 +CC(CO)C(C)NC(=O)Nc1cccc(S(=O)(=O)C(F)F)c1 +Cc1ccc(C(C)NC(=O)NCc2cn3cc(Cl)ccc3n2)o1 +CN(C)Cc1c(O)c(=O)cc(CO)n1C(C)(C)CO +N#Cc1ccccc1OCC(=O)OCC1CC=CCC1 +Cc1csc(C(OC(=O)CC(C)(C)C)C(F)(F)F)n1 +O=C(CN1CCCCC1=O)Nc1ccc(Oc2ccccc2)cc1 +O=C(NCCCn1cnc2ccccc21)c1cc2c(s1)CCC2 +CCc1cccc(CC(=O)Nc2c(C)noc2CC)c1 +CC(Oc1ccccc1Cl)C(=O)NCC1CC1 +CC(NS(=O)(=O)N1CCCCCC1)C(=O)NCc1ccccc1 +CCCn1ncc(C(=O)Nc2ccc3c(c2)COC3)c1C1CC1 +Cc1nc2cc(NCc3ccccc3F)ccc2o1 +CCN(CC)C(=O)CC1CSc2nc(C)cc(=O)n21 +CC(C)NC(=O)c1ccc(-c2cccc(F)c2)nc1 +CC(CCc1ccc(O)cc1)NC(=O)Nc1cccnc1 +Cc1ccc2c(COC(=O)Cc3c(C)noc3C)cc(=O)oc2c1C +CC(OC(=O)c1cc(S(=O)(=O)N(C)C)ccc1F)C(N)=O +Cc1c(C(=O)NCc2csc(=O)[nH]2)c(=O)oc2ccccc12 +CC(CO)N1CCN(C)c2cc(Br)ccc21 +O=C(Nc1ccc(N2CCNC2=O)cc1)c1cccc2ncccc12 +COC(=O)c1cc(-c2csc(NC(=O)C3CC=CC3)n2)c[nH]1 +CN(C)c1cc(C(F)(F)F)nc(N2CCC(NC(N)=O)CC2)n1 +O=C(Nc1nncs1)c1cccc(S(=O)(=O)N2CCCC2)c1 +O=C(CN1C(=O)CCOc2ccccc21)Nc1nc2ccccc2[nH]1 +COc1cc(OC)c(NS(=O)(=O)c2ccc(F)c(F)c2)cc1F +COc1ccc(CNC(=O)c2cnc3ccoc3c2)cc1 +CC(C)c1cc(C(=O)OCC2CC(=O)N(C3CC3)C2)nn1C(C)(C)C +CC(Sc1ncnc2c1cnn2C)C(=O)NC(C)c1ccccc1 +Cn1cc(S(=O)(=O)NC(c2ccc3c(c2)OCCO3)C2CC2)cn1 +CC(NS(=O)(=O)Cc1cccc(N)c1)C1CC1 +O=C1CC(c2nc3ccccc3[nH]2)CN1c1cccc(Cl)c1 +CC(NC(=O)c1cccc(-c2ccoc2)c1)C(=O)OC1CCCC1 +O=S(=O)(c1cccc(-n2cnnn2)c1)N1CCC1c1ccccc1 +CCn1nc(C)cc1C(=O)NCC(=O)N(C)Cc1cccc(F)c1 +O=C(NCc1ccccc1OC(F)(F)F)NC1CCC(O)CC1 +Cc1ccc(CN(C(=O)NCCCn2cccn2)C2CC2)cc1C +Cc1nc(C(C)C)sc1C(=O)NCCN1CCNC1=O +COc1ccccc1C(=O)NCCC(=O)N1CC(C)OC(C)C1 +CC1CC1c1ccc(CN(Cc2nnc(-c3ccco3)o2)C2CC2)o1 +CCc1ccc(NC(=O)C2CCCN(S(=O)(=O)N(C)C)C2)cc1 +CCCc1nc(C)c(C(=O)NCc2ccc(N3CCCC3)nc2)s1 +CC1c2ccc(F)cc2CCN1C(=O)C1CCCOC1 +CC(C)c1csc(C(=O)N2CCn3c(C(N)=O)cnc3C2)n1 +CNC(=O)c1ccccc1-c1nc(-c2ccc(F)cc2)no1 +CCC(C)(C#N)NC(=O)c1ccc(OC)c(F)c1 +Cc1csc(NC(=O)c2nc(N)ccc2Cl)n1 +CCN(C(=O)c1cccc(C)n1)c1ccccc1N +CS(=O)(=O)NCc1ccc(C(=O)c2ccccc2)s1 +COc1ccc(OCc2nc(C(=O)N3CCC(C)CC3)cs2)cc1 +COc1cc2oc3ccccc3c(=O)c2cc1OC +CN(Cc1ccc(Br)cc1)C(=O)c1ccncc1 +COc1cccc(OC)c1OC(=O)c1ccc2c(c1)OCCO2 +COc1ccc(-n2nc(C)c3c2N=C(O)CC3c2ccccc2C)nn1 +CCCn1nc(C(=O)NC(CC)c2ccccc2OC)ccc1=O +C#CCN(C)C(=O)c1nc(C)n(-c2ccccc2C)n1 +CC1(C)CCC(CNC(=O)CCCCNC(N)=O)CC1 +CC(=O)Nc1cc(NC(=O)NCCc2ccncc2C)c(F)cc1F +O=S(=O)(NCc1ccccc1)N1CCN(CC2CCCO2)CC1 +O=C(NC1CC1)c1cccc(NC(=O)c2ccco2)c1 +O=c1[nH]c(=O)n(Cc2ccco2)c2c1CN(Cc1ccco1)CN2 +O=C(Nc1nc[nH]n1)c1cccc(C(F)(F)F)c1 +Cc1ccc(C(C)N(C)C(=O)CCc2c(C)nc(C)[nH]c2=O)cc1 +COc1ccc(F)cc1NC(=O)c1ccc2ccccc2n1 +Cc1noc(C)c1CCC(=O)N1CCC(Oc2cnccn2)CC1 +O=C(NC1CCCc2c1cnn2Cc1ccccc1)c1n[nH]c(=O)[nH]1 +COC(=O)C(O)Cc1sc(-c2ccccc2Cl)nc1C +CN(Cc1cnccn1)S(=O)(=O)c1ccc(C#N)cc1Cl +CN(Cc1ccccc1)C(=O)c1cc2cnc3[nH]ccc3c2n1C +CC(=O)Nc1ccc(OC(C)=O)c2c1ncn2C(C)=O +CN(C)C(=O)C1CCCN(C(=O)c2ccncc2)C1 +COc1ccc(-n2nnnc2SCC2CCOCC2)cc1 +Fc1cc(C(F)(F)F)cc2c1C(c1cc[nH]n1)NCC2 +COc1cccc(OC)c1C(=O)c1cccc(C)n1 +CCOc1cccc(CNC(=O)c2cn(C)nc2C(C)(C)C)c1 +CCc1noc(CC)c1CC(=O)N1CCC(N2CCCC2=O)CC1 +Cn1cccc1Cc1nnc(SCC(=O)NCC2CCCO2)n1C +N#CCCN(C(=O)c1ccc(Cl)cc1N)c1ccccc1 +N#Cc1ccc(C(=O)NCC(=O)N2CCCc3ccccc32)cc1 +CN(C(=O)Cn1nnc2ccccc2c1=O)c1cccc2ccccc12 +CCCNC(=O)c1cccc(NC(=O)NCc2ncn(C)n2)c1 +O=C(CC1CC1)N1CCC2(CC1)CN(c1ncccn1)CCO2 +CN(C(=O)OC(C)(C)C)C1CCN(c2ncccc2O)CC1 +Cc1cc(C)n(CC(C)CNC(=O)NC(C(N)=O)c2ccccc2)n1 +CCN(c1ccc(F)c(F)c1)S(=O)(=O)c1ccc(C(N)=O)cc1 +NC(=O)CCCNC(=O)Cn1nnc2ccccc21 +COc1cc2c(cc1OC)C1(CC1)CNC2c1ccccn1 +Nn1c(C(F)(F)F)nc2cc(C(F)(F)F)ccc21 +CSc1ccc(OC(=O)Cc2csc(C(C)C)n2)cc1 +COCC(NC(=O)Nc1cc(F)c(OC)cc1OC)c1ccco1 +CCC(NS(=O)(=O)c1cnn(C)c1)c1cccc(Cl)c1 +CCOC(=O)Cc1ccccc1NC(=O)c1cccn1C +Nc1ccc2oc(-c3ccccc3Br)nc2c1 +CC1CCCN(C(=O)CCCn2cnc3c2c(=O)n(C)c(=O)n3C)C1 +CC(=O)c1ccccc1OCC(=O)c1ccc(C)cc1 +COC(=O)Nc1c(-c2ccccc2)nc2ncccn12 +COc1ccccc1C(=O)NCC(=O)NCCc1cccs1 +CC1(C)OC(=O)Nc2ccc(Br)cc21 +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)OCCCc1ccccc1 +Cc1nc(-c2nc[nH]n2)sc1C(=O)OCC1CC1 +COc1ccccc1N1CCN(C(=O)c2cc(C)ccc2C)CC1 +COc1ccc(F)cc1C(O)CCCC(=O)NC(C)C +CC(C)N(C(=O)CSc1ncnc2c1nnn2C)C(C)C +Cc1nc(CN(C)C(=O)c2cc(Br)c[nH]2)cs1 +Cc1ccc(NC(=O)c2cc3nc(C)ccc3o2)cc1 +CCN(CC1CC1)C(=O)C(C)NS(=O)(=O)c1ccccc1 +Cc1noc(C)c1C(C)NC(=O)c1csc(-c2cnn(C)c2)n1 +COc1ccccc1CNS(=O)(=O)c1cccc(C(=O)N(C)C)c1 +O=C1CN(C(=O)CSc2ccncn2)c2ccccc2N1 +CC1CCN(C(=O)CCNC(=O)c2cccs2)CC1 +Cc1cc(NC(=O)c2ccc(F)cc2)nn1Cc1ccccc1 +CCOC(=O)c1ccsc1NC(=O)c1cnccn1 +Cc1ncsc1C(=O)N(C)Cc1csc(-c2ccccc2)n1 +CC(C)Cc1nnc(NC(=O)c2cc3ccccn3n2)s1 +COC(C)c1cccc(NC(=O)c2ccc(C(=O)N(C)C)cc2)c1 +COC(=O)CCCn1c(C(C)C)nc2cc(OC)ccc21 +O=C(NCCc1ccoc1)Nc1c(F)cccc1F +CCCn1c(C)nnc1SCC(=O)Nc1cc(C(C)(C)C)no1 +Cc1cc(NC(=O)c2ccco2)ccc1NC(=O)c1ccco1 +CCOc1c(Cl)cccc1NC(=O)c1ccoc1 +Cc1nc2ccc(NC(=O)N3CC(C)OC(C)(C)C3)cc2o1 +CSc1cccc(NC(=O)N2CCCC(CNC(=O)C(C)C)C2)c1 +CCN(CC)C(=O)C1CCN(C(=O)Nc2cccnc2OC)CC1 +CCCS(=O)(=O)N(C)CC(=O)Nc1cccc(OC)c1 +NC(=O)NCCCCC(=O)NC1CCCNC1=O +CC1CN(C(=O)C2CCN(c3ccc(Cl)cn3)CC2)CCO1 +Cc1ccccc1C(C)NC(=O)c1scnc1C1CC1 +Cc1csc(CNC(=O)N(Cc2ccc(F)cc2F)C2CC2)n1 +CCOc1cc(NC(=O)CC(C)(C)C)ccc1OC +COc1ccc(NC(=O)CN2C(=O)C(C)Oc3ccccc32)cn1 +COCCCn1ccc2c(nnc3c(-c4ccccc4)c(C)nn32)c1=O +Cc1noc(C)c1C1CC(O)=Nc2c1cnn2Cc1ccccc1 +CC(c1cccnc1)N(C)C(=O)CNc1cccc(C(F)(F)F)c1 +CNc1cccc(C(=O)NC(C)c2cccnc2)n1 +CNC(=O)c1ccsc1NC(=O)CSc1ccc(OC)cc1 +O=C(Cc1cccc(F)c1F)N(CC(F)(F)F)c1ccccn1 +CC(=O)NCCNC(=O)Nc1cccc(C)c1C(=O)N1CCCC1 +CCC(C)OC(=O)Cn1cc(CO)c2cc(C)ccc21 +O=C(CNC(=O)c1ccc(N2CCCC2=O)cc1)NCc1ccco1 +CCN(C(=O)CC(NC(N)=O)c1cccs1)c1cc(C)cc(C)c1 +COc1cccc(C(=O)Nc2ccccc2Cc2nc(C)no2)c1 +COc1ccc(CNC(=O)CSc2nncn2C)cc1 +Cc1nnc(SCc2ccc(C(=O)OC(C)C)cc2)n(N)c1=O +CCCn1c(C)nnc1SCC(=O)N(CC)CC +COCCOC1CCN(C(=O)c2ccoc2)C1Cc1cnn(C)c1 +CCc1cc(N2CCN(C(=O)OC(C)(C)C)CC2)n2ncnc2n1 +CC(=O)Nc1cccc(NC(=O)C2CC2(Cl)Cl)c1 +NC(=O)c1ccc(NC(=O)Cc2c(F)cccc2F)cc1Cl +CCc1noc(CSc2nc(-c3ccc(OC)cc3OC)n[nH]2)n1 +CCn1nc(-c2ccc(OC)c(OC)c2OC)cc(N)c1=O +CCn1nc(C)c(NCc2ccc(Oc3cnccn3)cc2)c1C +CC(OC1CCCCCC1)C(=O)Nc1ccc(C(N)=O)cc1F +Cc1nc(-c2cc(C(=O)Nc3ccc4c(c3)COC4)co2)cs1 +O=C1NCCCCC1NC(=O)N1CCC1c1ccc(Cl)cc1 +O=C(NCc1ccccc1F)N(Cc1ccncc1)CC1CCCO1 +Cc1ccc(C(CNCc2cccnc2)N2CCOCC2)s1 +CCc1nn(C)c(CC)c1CN1CCN(c2nc(C)ns2)CC1 +CCOc1cc(CNc2cc(F)ccc2F)ccc1O +CCc1nc2nnc3c(=O)n(-c4cccc(C(C)=O)c4)ccc3n2n1 +CC(=O)c1cc2cc(C(=O)Nc3cccc(F)c3)cnc2[nH]1 +CN(Cc1cccs1)C(=O)c1cccc(-c2nnnn2C)c1 +C=CCCC(=O)N1CCC(c2nnc(Cn3cncn3)n2CC)CC1 +CC(=O)OC1CSc2ccccc2N(C(C)=O)C1 +Cc1cc(C)c(C(=O)NCc2ccnc(OC3CCC3)c2)o1 +CCc1nnc(NC(=O)Cn2c(C)ccc2C)s1 +O=C(Cn1nnnc1CN1CCOCC1)NCc1cccc(F)c1 +CCCc1cc2c(cc1CC1(C(C)=O)CCOC1=O)OCO2 +Cc1cccc(C(=O)N2CCC(c3cc(N)on3)CC2)c1 +CCC(NC(=O)c1ccc(=O)n(C)c1)C1CCCO1 +COc1ccc(NC(=O)Cc2c(C)nc3cc(=O)[nH]n3c2C)cc1C +CCNC(=O)C(N)c1ccc(OCC)c(OC)c1 +N#Cc1ccc(C(=O)Nc2ccc3c(c2)CC(=O)N3)cc1 +CN(C)C(=O)CN(C)C(=O)C1(c2ccc(F)cc2)CCC1 +COc1ccc(C)nc1NC(=O)c1cnn(-c2ccccc2)c1 +CC(C)C(Sc1n[nH]c(N)n1)C(=O)N1CCc2ccccc21 +Cc1ccc(C(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C +Cc1ccc(-c2n[nH]c(=O)c3ccccc23)cc1S(N)(=O)=O +Cn1cc(N2CCN(C(=O)Nc3ccncc3F)CC2)cn1 +Cc1cc(=O)n(CC(=O)NCCC(C)C)c(-c2cccc(Cl)c2)n1 +C#CCN(Cc1ccco1)C(=O)c1cc(C(C)=O)c[nH]1 +CCN(Cc1cccs1)Cc1cc(=O)oc2cc(OC)ccc12 +O=C(NCC(O)c1cccc(C(F)(F)F)c1)C1CC1c1ccco1 +CC(NC(=O)CN1CCN(CCO)CC1)c1cc2ccccc2o1 +O=C(NCc1ccccc1)c1cnn2c(-c3ccccc3F)ccnc12 +CCOc1ccc(F)c(C(=O)N2CCOCC2)c1F +N#CCS(=O)(=O)NCC1(Sc2ccccc2)CCCC1 +COc1csc(C(=O)NCc2ncn(C)n2)c1 +COc1cc2c(cc1F)C(c1cccc(C#N)c1)NCC2 +O=C(NCc1ccc(C(=O)N2CCCC2)cc1)c1cnc2ccoc2c1 +CCCCn1nc(C(=O)OCC(=O)N2CCCC2)ccc1=O +CN(C(=O)c1ccc(-n2ccnn2)cc1)c1ccc(Cl)cn1 +COc1ccc(C(C)N(C)C(=O)NCc2ccnc(OC)c2)cc1 +Cc1ccc(C(=O)N2CC(C)OC(C)C2)c(O)c1C +CC(c1ccc(F)c(F)c1)N(C)C(=O)COc1ccc(C#N)c(F)c1 +Cn1cc(CC(=O)NCc2cccnc2)c2cccnc21 +CCc1cc(C(C#N)N2CCOC2=O)ccc1OC +Cc1c(Cl)cccc1NC(=O)COc1ccccc1N +CCOCC(=O)NCc1cc(-c2ccncc2)n(C)n1 +CCn1cnnc1CNC(=O)NC1CCSc2c(F)cccc21 +CN(C(=O)CCNC(=O)C1CCCC1)C1(C#N)CCC1 +CC(C)CCS(=O)(=O)NCc1ccc(F)cc1 +Cc1cnc(CNC(=O)Nc2ccc(Oc3cccnc3)nc2)s1 +CN(C)S(=O)(=O)N1CCCC(c2nccs2)C1 +CCCn1cnc2cc(NC(=O)c3cccs3)ccc21 +Cc1cc(S(=O)(=O)NCCn2ncccc2=O)ccc1F +CN(Cc1cccs1)C(=O)c1cc(NC(=O)C2CC2)n(C)n1 +CCC(C)NC(=O)CC(c1ccc(OC)cc1)n1cccc1 +Cc1cc(NC(=O)c2ccc(-n3nc(C)cc3C)cc2)n(CCC#N)n1 +CCCc1cc(C2CCCN2C(=O)c2cccc(F)c2)no1 +O=C1CN(C(=O)CSc2ncc(-c3ccc(F)cc3)o2)CCN1 +CC(N)C(=O)OCCc1ccc2nc(C(C)C)[nH]c2c1 +CCC1CCCN(C(=O)Nc2cc(OC)c(OC)cc2C)C1 +CCC(=O)Nc1ccc2c(c1)N(C(C)=O)c1ccccc1CC2 +O=C(CCSc1nnc2c(n1)[nH]c1ccccc12)N1CCCC1 +Fc1cccc2nc(C(F)(F)F)n(-c3ccncc3)c12 +O=C(CC1CCCC1)N1CCC(c2nc(-c3ccncc3)no2)C1 +CC(=O)Nc1ccc(C(=O)Nc2ccc(C)cc2C)s1 +N#Cc1cccc(CNC(=O)NCCc2ccccc2F)c1 +CC(C)Oc1cncc(C(=O)N2CCOCC2)c1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(C)c(C(N)=O)c1 +Cn1c(=O)oc2cc(-c3noc(-c4cccs4)n3)ccc21 +Cc1ccc(C(C)NC(=O)CCNC(=O)c2ccsc2)cc1F +COc1ccc(CSc2nc(C)nc(C)c2C#N)cc1F +CN(CCC#N)CC(=O)N(C)Cc1cccs1 +Cc1cc(C(=O)N2CC3CCC2C3Oc2ccccn2)c(C)o1 +CC(C)(C)c1ccc(OC2CC2)c(=NS(C)(=O)=O)[nH]1 +CC(O)CNC(=O)CCc1ccc(Cl)cc1Cl +O=C(NCC(F)(F)F)C1CC(=O)N(CC(F)(F)F)C1 +Cc1ccc(N(C)CC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c(C)c1 +CC(C)c1nnc(CN2C(=O)c3cccc4cccc2c34)o1 +CCNS(=O)(=O)c1cccc(C(=O)N(CC)CC)c1 +O=C(NCc1cccs1)c1cccc(Oc2ccccn2)c1 +CC1CCCN(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)C1 +O=C(Nc1ccc(NCCO)nc1)c1c(F)cccc1Cl +Cc1cc(NC(=O)C(C)CC2CCCCC2)n(C)n1 +CCn1nc(C)cc1C(=O)NCC(=O)NCc1nc2ccccc2[nH]1 +Nc1ccc(NC(=O)C2CCOCC2)c(Cl)c1 +CC(=O)c1ccc(C(=O)Nc2nnc3n2CCCC3)cc1 +CCOc1ccc(F)c(C(=O)NCc2cccc(NC(C)=O)c2)c1F +Cc1ccc(C(O)CNS(=O)(=O)c2cccs2)o1 +COCc1nc(C(=O)N2CCCCCC2c2ccncc2)cs1 +CNC(=O)Cn1nc(-c2ccc(OC)cc2)ccc1=O +Cc1ccc(C(=O)OCCNc2cccnn2)cc1F +CCC(CC)NC(=O)c1cc(C)nc2c1nc1n2CCCCC1 +CC(C(=O)N(C)CCC#N)N(C)Cc1ccc(C#N)cc1 +O=C(C1CC1)N1CCCn2nc(-c3cccnc3)cc2C1 +CCNC(=O)N1CCCC(c2cccc(C(=O)NCCCOC)c2)C1 +COc1ccc(OCCN(C)C(=O)Nc2ccc3c(c2)COC3)cc1 +COc1ccc(CN(C)C(=O)c2ccc(N3CCCC3=O)cc2)cc1 +CC(CNC(=O)Nc1cc(C(C)(C)C)on1)c1nccs1 +Cc1ccc2c(CC(=O)Nc3ncccc3C)coc2c1 +CC(C)OCCC(=O)Nc1cc(-c2ccccc2)nn1C(C)C +O=S(=O)(N=c1ccc(CO)c[nH]1)c1ccccc1Cl +O=C(CCn1cccn1)Nc1ccc(-n2ccnc2)nc1 +Cc1cccc(CN2CCN(C(=O)c3ccoc3)CC2)c1 +O=C(NCCc1cccnc1)C1COC(=O)N1CC1CCOC1 +CCCc1ccc(-c2nccn2Cc2c(C)noc2C)o1 +CCN(Cc1ccncc1)C(=O)CCc1scnc1C +CC(CC#N)N(C)C(=O)Nc1nnc(C(C)(C)c2ccccc2)s1 +CC(Cc1ccccc1F)NC(=O)c1cc(-c2ccco2)[nH]n1 +Cc1cc(-c2noc(Cn3cnc(C4CCC4)cc3=O)n2)ccc1F +Cc1ccc(C(=O)NCCCc2cc(N)n(-c3ccccc3)n2)n1C +Nc1cccc(Cn2ccnc2Cc2ccc(Cl)cc2)c1 +CCOc1ccccc1OC(=O)CCc1c(C)nc2ncnn2c1C +CCCc1cc(C(=O)N2Cc3ccccc3CC2C(N)=O)sc1C +COC(=O)c1csc(S(=O)(=O)N2CCOCC2)c1OC +Cc1ccc(C)c(C(=O)OCC(=O)Nc2sccc2C(N)=O)c1 +Cc1cc(OCC(=O)Nc2ccc3c(c2)OCC(=O)N3)ccc1Cl +COc1ccc(C)cc1CN(C)C(=O)CC1C(=O)Nc2ccccc21 +CCOc1ccc(F)c(C(=O)Nc2ccc3nc(C)oc3c2)c1F +CC1Nc2cc(Br)ccc2N(CCO)C1=O +O=C(OC1OCCCC1O)c1cccc(Cl)c1 +CCC1CCCCN1C(=O)NCc1ccnn1C +COc1ccc(SC(C)C(=O)Nc2ncccc2NC(C)=O)cc1 +CC(c1ccccc1)N(CC(N)=O)C(=O)c1scnc1C1CC1 +CC(NC(=O)Cn1c(=O)oc2ccc(Cl)cc21)c1ccccc1 +Cc1cccc(C(=O)Nc2cccc(C#N)c2)c1N +CC(Cc1c(F)cccc1F)NCc1cnn(C)c1 +Cc1ccccc1CC(=O)Nc1ccc(CCC(=O)N(C)C)cc1 +CC(=O)Nc1cccc(NCC(=O)Nc2cc(C)on2)c1 +Cc1cc(C)c2cc(C(=O)N(C)CC3(C)COC3)[nH]c2c1 +COc1ccccc1-n1nnc(C(=O)NC(C)C)c1C +O=C(Cc1ccc[nH]1)NC1CCc2c(Cl)cccc21 +CCC(CC)NC(=O)C1CCCN(S(=O)(=O)CC)C1 +COC(=O)c1cc2c(C)cc3ccccn3c-2c1C(=O)OC +O=C(NCc1nnc2c(C(F)(F)F)cc(Cl)cn12)C1CCC1 +Cn1cnnc1-c1cncc(NCc2cc3cc(F)ccc3o2)c1 +Cc1ccc(C2NC(=O)c3c(C)cccc3N2)cc1 +COc1cc(C(=O)N2CCOCC2)cc2occc12 +CN(Cc1ccc(F)c(F)c1)C(=O)c1c[nH]nc1-c1ccccc1 +Cc1nc(-c2ccncc2)cc(N(C)Cc2ccccc2)n1 +COCCNC(=O)C1CCC(C)N(C(=O)c2ccc(F)c(F)c2)C1 +Nc1ccnc(CNC(=O)CC=Cc2ccc(F)cc2)n1 +O=C1CCc2cc(NC(=O)NCC3(c4ccccc4)CC3)ccc2N1 +O=C(NCC(=O)N1CCc2ccccc21)c1cnc2snnc2c1 +O=C(Nc1ccc(-n2cccn2)c(Cl)c1)c1scnc1C1CC1 +Cc1ccc(OCC(=O)NCCC2=CCCCC2)c(-n2cnnc2)c1 +Cc1ccc(C(=O)Nc2c(C)nc3c(C)cccn3c2=O)cc1C +CCc1c(C)nc(-c2cnccn2)n2c(=O)[nH]nc12 +COc1cccc(CNC(=O)C2(c3ccc(Cl)cc3)CC2)c1OC +Cn1ccc(-c2nnc(NC(=O)c3ccccc3S(C)(=O)=O)o2)n1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)c1ccccc1F +COC(=O)c1ccc(CN(C)C(=O)CC(C)(C)C)cc1 +O=C(CCc1nc(-c2ccccc2Cl)no1)Nc1nc[nH]n1 +CC(=O)c1cc(C(=O)Nc2ccc3[nH]c(C)cc3c2)n(C)c1 +CCOC(=O)Cn1cnc2c(cnn2-c2ccccc2)c1=O +COc1ccccc1COC(=O)CNC(=O)c1ccccc1 +CC(C)(C)Oc1ccccc1NCc1noc(-c2ccoc2)n1 +CCOc1ccc(C(=O)N2CCC(c3ccncc3)CC2)cc1 +CCN(CCC(=O)OC)C(=O)c1ccc(Br)cc1F +O=C(Nc1ccc2c(c1)OC1(CCCCC1)O2)c1cnccn1 +O=C(NC1CCOc2ccccc21)c1cc2ccccc2[nH]1 +CC(=O)c1cccc(S(=O)(=O)NCCC(C)(C)C)c1 +Cn1cc(-c2nc(C(=O)NCCc3ccc(O)cc3)cs2)cn1 +Cc1cc(NC(C)c2ccc(-n3cncn3)cc2)nc(C)n1 +Cn1c(=O)[nH]c(=O)c2[nH]c(CN3CCOCC3)nc21 +C=CCn1nnc(C#N)c1COc1ccc(CC)cc1 +Cc1nnc(SCC(=O)NC2CCCCC2)n1-n1cccc1 +CCN(CC)C(=O)c1cnc(-c2ccccc2)nc1N(C)C +Cc1cccc(C)c1NC(=O)NCc1cnn(C)c1 +CC(=O)Nc1nonc1-c1nc2ccccc2n1CCCCC#N +Cc1ccc(N2C(=O)CCC2(C(N)=O)c2ccccc2)cc1 +O=C(Nc1ccc(Br)c(C(F)(F)F)c1)c1cc[nH]n1 +Cc1ccc(CN2Cc3c(N)cccc3C2=O)cc1 +O=C(NCCN1CCOCC1)NC(c1ccccc1F)C1CCCC1 +Cn1nncc1CNCC(O)c1ccc(F)c(F)c1 +COc1ccc(C(=O)COC(=O)c2ccccc2)cc1 +CC1CN(C(=O)C2(c3ccc(F)cc3F)CCOCC2)C(C)CO1 +COCCOc1ccc(NC(=O)NCc2ccnn2C)cc1F +CCOc1ccccc1N(C)C(=O)c1ccc(Cl)cn1 +O=C(NCCN1CCOCC1)Nc1ccc(Cl)c(Cl)c1 +COc1ccc(NC(=O)CN(C)C(=O)c2ccccc2)cc1 +CC(=O)c1cccc(NC(=O)c2csnc2C)c1 +CN(CCN1CCCC1=O)C(=O)c1cccc(Br)c1 +O=C(CCc1ccccc1)N1CCC(Oc2ncccn2)CC1 +CCc1ccc(-c2csc(NC(=O)CCn3cncn3)n2)s1 +COc1ccc(C)cc1NC(=O)c1cc(C)nc2c1cnn2C(C)C +CCCC(C#N)NC(=O)c1cc2ccccc2n1C +O=C(NCC1(COc2cnccn2)CC(O)C(O)C1)C1CC1 +CC(C)c1cc(NC(=O)C2CC2c2ccco2)[nH]n1 +COc1ncc(NC(=O)Cc2ccc(Cl)cc2)cn1 +CCCOCCOc1ccc(Br)cc1N +Cn1cc(C(=O)Nc2cccc3ccccc23)c(=O)c2ccccc21 +CCCCN(C)c1ncnc(-n2nc(C)cc2C)c1N +COc1ccccc1OCCC(=O)NCc1cc(C)oc1C +O=C(c1cnns1)N1CCN(c2ncccc2Cl)CC1 +NC(=O)Cc1ccccc1NC(=O)NCC(=O)Nc1ccccc1 +Cc1ccc(N2CC(C)N(C(=O)c3cnccn3)CC2=O)cc1 +Cc1nc(C2(NS(=O)(=O)c3ccc(C#N)cc3)CCCCC2)no1 +Cc1ccc(C(=O)CCc2nc(C)c(C)s2)cc1C +CC(OC(=O)c1cccn1C)C(=O)Nc1ccccc1F +O=C(CSc1nccn1-c1ccc(F)cc1)Nc1ccccc1 +Cc1nn(C(C)C)c(C)c1NC(=O)NCc1nnc2ccccn12 +CC1CN(S(=O)(=O)N2CCN(CCC#N)CC2)CC(C)O1 +CCOc1ccc(CN2CCN(C(=O)c3cn[nH]n3)CC2)cc1 +Cc1cccn2c(=O)nc(SCC(=O)Nc3ccccc3)nc12 +O=C(CCCN1CCOC1=O)Nc1ccc2[nH]ncc2c1 +CC(C)c1ccc2c(c1)CNCC2C(=O)NC(C)(C)CO +Cc1nc(NCc2ccccc2)cc(OCC(C)C)n1 +Oc1cccc(C2CN(Cc3cccc(-c4ccncc4)c3)CCO2)c1 +C#CCN1CCN(CC(=O)NC(C)c2ccccc2OC)CC1 +CC(NC(=O)CCCNC(=O)C1CC1)c1ccc(C#N)cc1 +CN(CCc1cccs1)C(=O)NC1CCN(C)C1=O +N#Cc1cccc(NC(=O)c2ccccc2SCC2CCCO2)c1 +COCCNC(=O)c1onc(-c2ccccc2F)c1N +Cc1cc(C(=O)Cn2ccccc2=O)c(C)n1Cc1ccccc1 +Cc1ccncc1NC(=O)NC1CC(=O)N(CC(F)(F)F)C1 +Cc1ccc(-c2nc(NC(=O)C3CC3)sc2C)cc1 +Cc1ccc(OCC(=O)NC(C#N)c2ccc(F)cc2)cc1 +CC(CNC(=O)NCc1ncn(C)n1)c1cccs1 +COc1ccc(C(=O)Nc2sccc2C#N)cc1Br +Cc1cccc(OCCCC(C#N)C(=O)N2CCCC2)c1C +CCc1noc(CC)c1CNC(=O)CN(C)C(C)=O +Cc1nc(-c2nnc(NC(=O)c3snnc3C)o2)cs1 +CCCCn1nc(C(=O)N2CC(C)c3ccccc32)ccc1=O +NC(=O)C(NCc1ccc(Cl)cc1Cl)c1ccc(F)cc1 +CCN(CC)S(=O)(=O)c1c(C)nn(C(=O)C2CCCCC2)c1C +CCc1cc(-c2cccc3ccnn23)nc(N2CCOCC2)n1 +CC(CO)NC(=O)C(NC(=O)NCc1ccccc1)C(C)C +CC(N)c1cc(=O)n2nc(C3CCOCC3)cc2[nH]1 +O=C1CC2(CCCCN2C(=O)C2CCCC2)CN1c1cccnc1 +N#CCCN(Cc1ccco1)C(=O)Nc1ccc(C(F)(F)F)cc1 +Cc1ccc(C2=CCN(C(=O)Cc3c(C)noc3C)CC2)cc1 +CC1CN(Cc2ccccc2NC(=O)c2csnn2)CC(C)O1 +O=C(c1cnccn1)N1CCCCC1c1nncn1Cc1ccccc1 +O=C(NCCO)NC1CCCN(Cc2ccccc2)C1=O +CCCc1ccc(C(=O)NCC2CN3CCCCC3CO2)cc1 +O=C(NCc1ccc(OC(F)(F)F)cc1)c1ccccn1 +CCCCn1nc(C(=O)NC(C)c2ccncc2)ccc1=O +Cc1cccc(C)c1NC(=O)c1onc(-c2ccccn2)c1N +Cc1ccc2cccc(OCC(=O)Nc3ccc(Cl)cc3)c2n1 +c1ccc(CNCC(c2cccs2)N2CCOCC2)nc1 +CCOc1ccc(-n2nnc(C(=O)OC)c2N)cc1OCC +O=C(NCc1ccccn1)Nc1cccc2cccnc12 +Cc1ccc(C)c(Cn2cccc(C(=O)Nc3cccc(C)n3)c2=O)c1 +COCCOc1cc(C)ccc1NC(=O)NCc1cccc(C#N)c1 +N#CCSc1nccn1-c1c(F)cccc1F +Cc1nnc2n1CCN(C(=O)Cn1nc(-c3cccs3)oc1=O)C2 +COC(=O)N1CC(NC(=O)c2ccc(-c3nc(C)cs3)cc2)C1 +COCc1cccc(C(=O)N2CCCC(CNC(=O)C(C)C)C2)c1 +CC(Sc1ccccn1)C(=O)Nc1cccc(F)c1F +Brc1ccc(OCc2n[nH]c(-c3ccncc3)n2)cc1 +O=C(Cc1cn2ccccc2n1)N(CCO)C1CC1 +O=C(CCc1c[nH]c2ccccc12)NCC(=O)NC1CC1 +Cc1cc(C(=O)c2cccc(C(F)(F)F)c2)c(N)o1 +CCCc1nnsc1C(=O)NCc1cc(-c2ccncc2)n(C)n1 +CCn1cc(CN2CC(C)OC(c3ccc(F)cc3)C2)cn1 +Cc1ccc(-c2ncco2)cc1NC(=O)CNC(=O)OC(C)(C)C +COc1cccc(CNC(c2ccccc2)c2ccncc2)c1 +COCCCn1cnc2c([nH]c3ccc(F)cc32)c1=O +CCc1cc(C(=O)Nc2nc(C(C)=O)cs2)sc1C +CCN1C(=O)Cc2cc(NS(=O)(=O)Cc3cccc(C)c3)ccc21 +CCN(C(=O)Nc1nc(C)cs1)C(C)c1ccc(F)cc1 +O=S(=O)(Cc1ccc(OC(F)F)cc1)c1ccccn1 +COC(=O)c1cccc(NC(=O)c2cccc(-n3cnnn3)c2)c1 +NC(=O)OCCNC(=O)C1(c2ccc(F)cc2F)CCC1 +C=CCNC(=O)Cn1cnc2c(cnn2-c2ccccc2)c1=O +Cc1nn(C)c(C)c1C(=O)NC1CCc2cc(F)ccc21 +O=C(CNc1cccc(Cl)c1)N1CCc2ccccc21 +NC(=O)CSc1nnc(-c2cccc(Cl)c2)n1N +CCn1nc(C)cc1C(=O)Nc1cc(C)cc2cccnc12 +COC(C)(C)c1noc(CCCNC(=O)c2ccc(Cl)cc2)n1 +CCc1nc2cc(C)nn2c2nc3ccccc3n12 +O=C(c1c(F)cccc1F)N1CCOc2ccc(F)cc21 +Cc1[nH]ncc1CCCNC(=O)CNC(=O)c1ccc(F)cc1F +COc1ccccc1C(=O)NCc1coc(-c2cccs2)n1 +NC(=O)CC1CCN(C(=O)Cn2ccc(C(F)(F)F)n2)CC1 +Cc1nc(C(=O)N2CCN(Cc3ccc(C)c(C)c3)CC2)c(C)o1 +CS(=O)(=O)N1CCCN(c2ccc(C#N)c(C(F)(F)F)c2)CC1 +Cc1nc2c(cc1C(=O)N1CCOC(C)C1)c(C)nn2C +COc1cc2c(C(=O)NCCCO)nccc2c(N)c1OC +CCCS(=O)(=O)N1CCCC(c2nncn2C)C1 +CCC(Oc1ccc(C)cc1)C(=O)Nc1ccc(N)cc1OC +Fc1ccc(OCc2nc(-c3cccnc3)n[nH]2)cc1 +CC(C)OCCCNC(=O)c1noc2c1COc1ccccc1-2 +CCOC(=O)c1ccc(NCc2cnn(C)c2)cc1 +Cc1cccc(SCc2ccc(C(N)=O)cc2)c1 +COCCCNC(=O)NC1(C(F)(F)F)Oc2ccccc2O1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)S(=O)(=O)c1ccccc1 +CCCn1c(SCC(=O)NC(C)C)nc2ccsc2c1=O +CC(=O)c1cc(Br)cc(F)c1OCC(=O)N1CCCC1 +Cc1ccccc1COC1CCN(C(=O)CC2CCOCC2)CC1 +CCOc1ccc(C(=O)N2CCN(C(=O)c3nonc3N)CC2)cc1 +COCc1nc2n(n1)CCCC2NC(=O)Nc1cnccc1C +C#CCN1CCN(Cc2cccc3c2OCCO3)CC1 +O=C(c1cccs1)N1CCCN(c2nc(C3CC3)ns2)CC1 +CS(=O)(=O)NCC(O)c1ccccc1C(F)(F)F +N#Cc1cccc(NC(=O)COc2nncc3ccccc23)c1 +Cc1cccc(N(C)S(=O)(=O)c2ccc3c(c2)OCCO3)c1 +CN1CCN(C(=O)CN(CCc2ccccc2)S(C)(=O)=O)CC1 +CCOC(=O)C(O)c1nnc(-c2ccncc2)n1C +c1cncc(-c2cccc(CN3CCOC(c4nccs4)C3)c2)c1 +CCCNC(=O)CNC(=O)Nc1ccc(F)c(C(=O)NC)c1 +O=C1COc2ccc(CO)cc2N1CCCc1ccccc1 +O=C(CCOc1cc(Cl)cc(Cl)c1)NCCO +CN(C)S(=O)(=O)c1ccc(Cl)cc1C(F)(F)F +CC(C)COC(=O)NCC1CCN(C(=O)c2ccoc2)CC1O +O=C(NCc1cnn(-c2ccccc2)c1)c1c[nH]cc1-c1ccccc1 +Cc1nc(C2(NC(=O)c3occc3C)CCCCC2)no1 +COCC(=O)Nc1cc(-c2cccc(C)c2)nn1-c1ccccc1 +NS(=O)(=O)CC1CCCN1C(=O)C1CCCCC1 +Cc1ccc(S(C)(=O)=O)cc1NCc1nc(C2CC2)no1 +N#Cc1ccc(OCC(=O)Nc2ccccc2Br)cc1 +Cc1ccc(N2CC(CNC(=O)C3CC3)CC2=O)cc1 +Cc1ccc(NC(=O)c2c(C)nc(C(C)(C)C)[nH]c2=O)cc1C +O=C(CCNS(=O)(=O)c1cccs1)Nc1nncs1 +Cc1sc(C(=O)Nc2cccc(O)c2)cc1S(=O)(=O)N(C)C +CN(C)C(=O)CCNC(=O)Nc1cc(C(C)(C)C)nn1C(C)(C)C +COc1cc(CNC(=O)CNC(=O)NCc2ccc(F)cc2)ccn1 +Cc1ccc(NCCC(=O)NC2CC2)cc1Cl +COc1ccccc1S(=O)(=O)Nc1cc(C(N)=O)ccc1C +O=S(=O)(NCc1ccccc1Cl)c1ccc(F)cc1F +Cc1ccc2c(c1)c(=O)n(C)c1nnc(CN3CCOCC3C)n21 +O=C(NCCn1ccc(C(F)(F)F)n1)Nc1cccs1 +CCC(CO)N1CCN(C(=O)c2ccn3ccnc3c2)CC1 +CCOC(=O)NCCC(=O)N1CCc2ccc(OC)cc2C1 +COc1cc(OC)nc(C2CCN(C(=O)C(C)(C)C)CC2)n1 +O=C(Nc1ccccc1)Nc1ccc(NC(=O)C2(O)CCCC2)cc1 +c1cc(Cn2cccn2)cc(NCc2cccc3cc[nH]c23)c1 +COC(=O)CCCCNC(=O)c1cnc(C)cn1 +Cc1nccn1-c1ccc(NC(=O)NCc2cccs2)cn1 +CCN(C(=O)c1cncc(N)c1C)c1ccccc1 +COC(=O)C(NCC(F)(F)F)C1CC=CCC1 +CC(Sc1nc(N)c(C#N)cc1C#N)C(=O)N1CCCCCC1 +Cc1cccc(-n2nnnc2SC(C)C(=O)N2CCC(C)CC2)c1 +COC(=O)CSc1nc2ccccc2n1CC(=O)N1CCOCC1 +CCOCCCNC(=O)Nc1c(F)cccc1F +CC(C)OC(=O)c1ccc(C2Nc3ccccc3S(=O)(=O)N2)cc1 +O=C(NCc1ccc(F)cc1)c1nccnc1C(=O)NCC1CCC1 +CC(C)(C)OCCCCSc1nc(N)c(C#N)cc1C#N +Cc1cc(C)c2c(n1)sc1c(N3CCN(CCO)CC3)ncnc12 +CCc1noc(CSc2nnc(-c3ccccc3)n2CC)n1 +Cc1nc(C2CC2)oc1C(=O)Nc1ccc(F)cc1OCC1CC1 +CN1CCN(S(=O)(=O)c2cc(F)c(F)cc2F)CC1 +CCCc1cc(N)n(-c2ccc(Br)cc2)n1 +COC(=O)C(CO)NCc1cc(F)c(F)c(F)c1 +COc1ccc(NC(=O)NCCc2nc(C(C)C)no2)cc1C +O=C(Nc1ccc2c(c1)COC2)C1CCN(c2ncccn2)CC1 +CC(C)Oc1ccc(C(=O)NC(c2ccccc2)c2ccncc2)cn1 +Cc1ccc(NC(=O)C2CC(=O)Nc3cc(F)ccc32)cc1Cl +COCCNC(=O)NCc1ccc(C(F)(F)F)cc1 +Cc1noc(CCCC(=O)NC(C)C2CCCO2)n1 +CNC(=O)CN1CCN(C(=O)CCSc2ccccc2)CC1 +COCc1cccc(C(=O)N(C)C2(C#N)CCC2)c1 +CCC(C)(C)C(=O)Nc1nnc(SCCOC)s1 +O=C(Cn1cc(Cl)cn1)c1ccc(F)cc1F +CN(Cc1cnc2ccccc2n1)C(=O)c1ncc(F)cc1F +CC(C)Oc1ccc(F)cc1NC(=O)c1ccc(-n2ccnn2)cc1 +O=C(CCc1cc(F)ccc1F)NCc1nncn1C1CC1 +Nc1c(Cl)cccc1C(=O)N1CCCCC1CCO +COc1c(C)cc(C)cc1C(=O)N1CCC(O)CC1 +O=C(CSc1nnc(-c2ccncc2)o1)Nc1ccc(Cl)cn1 +COCCC(=O)N1CCCC2(CCN(Cc3ccncc3)C2=O)C1 +CCc1ccc(C(C#N)CCC(=O)N2CCOCC2)cc1 +COc1ccc(OC)c(NC(=O)c2cccc3c2ccn3C)c1 +O=C1CNc2ncnc(NCCc3ccccc3)c2N1 +Cc1cc(NC(=O)CC#N)ccc1Br +CCOC(=O)C1CC(=O)N(c2cc(OC)c(Cl)cc2OC)C1 +CC(C)Cc1noc(C(C)NCc2cc(=O)c3cc(F)ccc3[nH]2)n1 +Cn1nc(C2CCCC2)cc1NC(=O)c1ccc(-n2cnnc2)cc1 +COc1ccc(CC(=O)Nc2ccc3c(C)cc(=O)oc3c2)cc1F +CCOC(N1CCCC1=O)n1nnc2ccccc21 +CC(=O)c1c(C)c[nH]c1Cc1[nH]cc(C)c1C(C)=O +N#Cc1ccc(F)cc1CN1CCCN(S(N)(=O)=O)CC1 +NC(=O)COc1cccc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)c1 +Cc1csc(=O)n1CCC(=O)Nc1ccccc1N +COc1cc(N)ccc1NC(=O)c1ccc(C)c(F)c1 +COCc1ccccc1NC(=O)Nc1cccc(OC)c1 +O=S(=O)(CCN1CCn2c(nnc2C2CC2)C1)c1ccccc1 +CS(=O)(=O)c1nccn1CCOc1ccccc1 +Cc1nc(C)n(C2CCCN(C(=O)c3cccc4cn[nH]c34)C2)n1 +COc1ccc(NC(=O)NC(C)(C)c2nc(C)c(C)s2)c(C)c1 +COc1ccc(C(=O)Cn2c(=NC(C)=O)n(C)c3ccccc32)cc1 +CC(=O)Nc1cccc(NCC(=O)Nc2c(C)cccc2C)c1 +CN(C)C(=O)c1csc(N2CCN(c3ccccc3)CC2)n1 +O=C(Nc1ccc(-n2cncn2)nc1)C1CC1c1ccc(Cl)cc1 +CC(=O)Nc1cccc(NCc2cc(Br)ccc2F)c1 +C=CCNC(=O)c1cnn(-c2ccc(-c3nc(C)no3)cn2)c1C +CCc1cc(=O)n2c(n1)SCC2CC(=O)Nc1nccs1 +Cc1cnccc1CCNC(=O)N1CCOCC1C1CC1 +CC(=O)Nc1ccc2nc(NC(=O)c3cc(C)ccc3C)sc2c1 +CCSc1nnc(-c2cn(C)nc2OC)n1C +COc1ccc(OCc2nn3c(-c4ccco4)nnc3s2)cc1 +COCc1cccc(C(=O)Nc2ccnn2Cc2cccc(C)c2)c1 +CCCc1nnc(NC(=O)c2cc(=O)c(OC)co2)s1 +COc1cc2c(cc1NC(=O)CCNC(C)=O)oc1ccccc12 +CC1CN(CCNC(=O)c2ccc(Cn3cncn3)cc2)CC(C)O1 +CC(NC(C)c1ccc(F)c(F)c1)C(=O)N(C(C)C)C(C)C +CCc1noc(CC)c1CNC(=O)c1coc(-c2csc(C)n2)c1 +CCS(=O)(=O)c1ccc(NCC(=O)NCc2ccccc2)cc1 +CC(C)Oc1ccc(-c2nc3ccc(O)cc3o2)cc1N +CCc1nc2cc(S(=O)(=O)NCC3CCCC3)ccc2o1 +COc1ccc(S(=O)(=O)CCc2nnc(NC(C)=O)s2)cc1 +CCCNC(=O)Nc1ccc(Cn2cccn2)cc1 +O=C(Nc1csc(Cc2ccsc2)n1)Oc1ccccc1 +CCCNC(=O)Nc1ccc(OCCOC)nc1 +CCOC(=O)Cn1cc(Cl)cc(Cl)c1=O +O=C(CCN1C(=O)CCc2ccccc21)Oc1ccc(Cl)cc1 +Cn1nccc1C1CCCN(Cc2ccc(-n3ccnc3)cc2)C1 +CCOC(=O)CSc1nc2ccccc2c(=O)n1CC(C)C +CC(=O)Nc1ccc(C)c(NC(=O)N2CCCC(NC(C)=O)C2)c1 +O=C(Cn1ccnn1)NC(c1ccc(Cl)cc1)c1ccsc1 +COCc1ccc(CNC(=O)CN(C)C(=O)OC)cc1 +CC(CO)NC(=O)Nc1ccc(N2CCOCC2)cc1C(F)(F)F +Cc1nc(-c2cccc(NC(=O)c3scnc3C3CC3)c2)cs1 +NC(=O)c1cc2c([nH]c1=O)CC(c1cccs1)CC2=O +CC1(C)COCCN1C(=O)CCC(=O)N(CCC#N)c1ccccc1 +Cc1cc(C(=O)NCC2CN(S(C)(=O)=O)CCO2)cnc1C +CNC(=O)CNc1ccccc1Sc1ccccc1 +O=C(c1ccnnc1)N1CCC2(CCNC2=O)CC1 +CC(=O)Nc1nnc(-c2ccccc2S(C)(=O)=O)o1 +Cc1ccnc(NC(=O)C2CCN(C(=O)c3cccs3)CC2)c1 +O=C(NCCOc1ccccc1)c1cc2cccnn2n1 +O=C(Nc1ccccc1)C1CCN(c2cc(-n3cncn3)ncn2)CC1 +CCCOc1nc(COC)nc(NC2CCCC2)c1N +c1cc2c(cc1-c1nn3cnnc3s1)OCCO2 +CCOC(=O)c1ccc(NC(=O)C2(n3cnnn3)CCCCC2)cc1 +COC1(C)CC(N(C)C(=O)CNC(=O)c2ccc(C#N)cc2)C1(C)C +CC(=O)N1CCN(C(=O)c2ccn(C(C)(C)C)c2)CC(O)C1 +Cc1nn(C)c(C)c1C(=O)NCCc1nc(-c2ccccc2)n[nH]1 +CC(=O)C(C)n1nc(C#N)cc1-c1ccc(Cl)c(C)c1 +CCOc1ncccc1CNC(=O)c1cc(NC(C)=O)ccc1F +CC1CCCCC1NC(=O)c1c(O)cc(F)cc1F +O=c1[nH]ncc(N2CCCC2)c1C=Cc1ccccc1 +O=C(CC1C=CCC1)Nc1cccn(Cc2ccc(F)cc2)c1=O +Fc1cc(Cl)c(NCc2nnc(C3CC3)o2)c(Cl)c1 +CC(=O)NCc1c(-c2ccc(Cl)cc2)nc2n1CCS2 +CCc1ccccc1CNC(=O)Nc1ccc(NC(C)=O)c(OC)c1 +COc1ccc(NC(=O)c2cnns2)cc1OCc1cccnc1 +Cc1ccc(F)cc1NC(=O)c1cc(C(N)=O)cn1C +O=C(CNS(=O)(=O)c1cc(F)c(F)cc1F)Nc1cccnc1 +COC(=O)C(C)(C)NC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 +Cc1ccnc2nc(C(=O)NCC3(c4ccc(F)cc4F)CC3)nn12 +CCNc1ncc(C(=O)N2CCC(Oc3cccc(C)c3)CC2)cn1 +CC1CCc2c(C(=O)NCCS(N)(=O)=O)csc2C1 +CCC(CC)C(=O)Nc1nc(C(F)(F)F)cs1 +CCOC(=O)C(CC)Sc1ncnc2ccsc12 +CNC(=O)c1cccc(CNc2ncnc3ccc(F)cc23)c1 +CCCNC(=O)CSc1nnc(SC)s1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccoc1C +COc1cc(CNC(=O)NC2(c3ccccc3F)CC2)ccn1 +CC(C)CCCNC(=O)Cn1nc(-c2ccccc2F)ccc1=O +Cc1ccc(C)c(SCC(=O)N(C)Cc2ccco2)c1 +Cc1ccc(C)c(C(=O)NCCS(N)(=O)=O)c1 +COc1ccc(CC(=O)NCC2(O)CCCCCC2)cc1 +CC(C)CN(C(=O)Cn1cnc2cc(F)ccc2c1=O)C1CC1 +N#CCCC(NC(=O)N1CCOCC1C1CC1)c1ccccc1 +Cc1ccc(C(C)NC(=O)CCc2cc(Cl)cs2)o1 +CS(=O)c1ccc(CNc2cnn(-c3ccccc3F)c2)cc1 +COC(=O)C1CC(C#N)(c2ccccc2)c2cccc(F)c2C1=N +Cc1ccc2c(c1F)C(c1c[nH]c(=O)c(Cl)c1)NCC2 +O=C(NCCc1c[nH]c2ccccc12)c1ccc(Cn2cccn2)cc1 +CCOC(=O)CC(C)CNC(=O)Nc1c(F)cccc1F +CCc1cccc(OCCCN(C)C(=O)c2cccnn2)c1 +CCOc1ccccc1NS(=O)(=O)Cc1ccccc1 +CSc1ccccc1NC(=O)COc1cccc(C(C)=O)c1 +O=C(NCCc1cccs1)C12COCC1CN(c1ncccn1)C2 +Cc1cc(C(=O)N(CCc2cccs2)Cc2ccco2)c(C)o1 +Cc1nn2cc(C(=O)NCC(=O)N3CCc4ccccc43)nc2s1 +COc1ccccc1-c1nc(-c2ccc(CNC(C)=O)s2)cs1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCc2ccon2)n1 +Cc1c(N2CCC(Cc3ccccc3)CC2)ccc2nc(N)nn12 +C=C(C)COc1ccccc1C(=O)N1CCOC(CCOC)C1 +O=C(CCSc1ccccc1)OCc1cc(=O)n2ccsc2n1 +CNc1ncnc(Oc2cc(C)c(Cl)c(C)c2)c1N +COc1ccccc1C1NCCc2c(F)cc(O)cc21 +Cc1cc(C)c(C)c(S(=O)(=O)NC2(C(N)=O)CCCC2)c1C +CSc1ccc(C)c(C(=O)Nc2cccc(C)c2C(N)=O)c1 +Cc1csc(NC(=O)NCC2(N3CCOCC3)CCCCC2)n1 +O=C(c1cccc(Cl)c1)N1CCN(Cc2ccccn2)CC1 +CCn1c(SCC(=O)Oc2ccccc2OC)nc2ccccc21 +CCOc1ccc(C2=CCN(C(=O)C(C)NC(N)=O)CC2)cc1 +CCC1CCCN(C(=O)Nc2ccc(Cn3cccn3)cc2)C1 +Cc1c(Cl)cccc1S(=O)(=O)N1CCOC(C)(C)C1 +CCCc1c(C(=O)NCC)[nH]c(C)c1C(=O)OC +CS(=O)(=O)N1CC(c2nc(-c3ccco3)no2)C1 +CC(C)(C)c1nc(CN2CCN(C3CCOC3=O)CC2)cs1 +CCCCN(C)C(=O)c1cc(N)n(-c2ccccc2)n1 +N#Cc1ccc(Cn2ccc(=O)c3sccc32)c(F)c1 +COC(=O)c1n[nH]cc1CN(C)Cc1nc2ccccc2c(=O)[nH]1 +CNC(=O)C1CCN(C(=O)Cc2nc(-c3ccccc3)oc2C)CC1 +Cc1cc(N)nc(SCC(=O)Nc2nc3c(s2)CCC3)n1 +COc1cccc(-c2nnn(Cc3noc(C4CC4)n3)n2)c1 +CC(=O)Nc1ccc(F)c(C(=O)N(C)c2cc(C)cc(C)c2)c1 +CCOCc1ccc(C(=O)Nc2sc(C)c(C)c2C(=O)OC)o1 +CC(C1CC1)N(C(=O)c1ccc(C(N)=O)nc1)C1CC1 +NS(=O)(=O)c1ccc(N2CCN(Cc3ccccc3)CC2)cc1 +O=C(Cn1ncc2ccccc2c1=O)N1CCCCC1c1cccnc1 +C#CCOc1ccc(CNc2ccc3c(c2)COC3)cc1 +CC(=O)NC(C(=O)NC(C)C12CC3CC(CC(C3)C1)C2)C(C)C +CCOc1ccc(CC(=O)NCc2nnnn2C2CCCCC2)cc1 +CC(=O)NCc1ccc(C(=O)N2CCc3ccc(Cl)cc3C2)cc1 +COc1c(C)cnc(CNS(=O)(=O)c2cc(C)ccc2C)c1C +c1cncc(-c2noc(-c3ccc4[nH]cnc4c3)n2)c1 +CCC(=O)N(C)c1nnc(-c2cccc(F)c2)s1 +COc1ccc2c(CSc3nnc(N)[nH]3)cc(=O)oc2c1 +Cc1cc(C)nc(SCC(=O)Nc2cccnc2N2CCCC2)n1 +COc1cccc(C(=O)NCc2ccc(F)cc2)c1OC +COC(=O)c1cccn2cc(CSc3nnc(C4CC4)n3C)nc12 +CCS(=O)(=O)c1ccccc1C(=O)Nc1sccc1C(N)=O +N#Cc1cccc(NC(=O)Nc2ccccc2Cl)c1 +CCCCS(=O)(=O)NCC(O)c1ccc2c(c1)OCO2 +CC(C)(C)C(=O)N1CC(c2nc(-c3ccco3)no2)C1 +CC(C)(CO)NC(=O)CCOc1ccccc1C(C)(C)C +CC(C)CN1C(=O)CCC2CN(C(=O)NCc3cccs3)CCC21 +Cc1cc(=O)c(C(=O)NC2CCCCCC2)nn1-c1ccccc1 +COC(=O)C(C)NC(=O)CCCc1cccs1 +COc1ccccc1CN(C(=O)c1ccnc(-n2cncn2)c1)C1CC1 +CCN(CC(=O)Nc1c(F)cccc1F)C(=O)Cc1ccsc1 +N#Cc1ccc(C(=O)NC2CCN(c3c(F)cccc3F)C2)nc1 +CCc1nnsc1C(=O)N(C)Cc1cccc(OC)c1 +Cc1noc2nc(C(C)C)cc(C(=O)N3CCOCC3)c12 +O=C(NCC1CC2CN(C(=O)c3ccno3)CC2O1)C1CCC1 +Cc1ccc(C)c(NC(=O)c2cc(S(N)(=O)=O)ccc2F)c1 +COCc1cc(=O)n(Cc2nnc(-c3ccccc3)s2)cn1 +N#CCCN1CCN(C(=O)c2ccc(OCc3ccccc3)cc2)CC1 +CC(=O)c1cccc(OCC(=O)Nc2ccc(F)cc2)c1 +Cn1c2ccc(N)cc2n2c(-c3ccc(N)cc3)nnc12 +Cc1ccc(NC(=O)CNS(=O)(=O)c2cnn(C)c2)cc1 +O=C(NCCO)C1CCN(C(=O)Nc2ccccc2)CC1 +Cc1nc2sccn2c(=O)c1NC(=O)CC1CCCC1 +Cc1cnc(C(NC(=O)N2CCCC(CO)C2)C2CC2)s1 +N#CC1(c2cccs2)CC(=O)CC1c1cccs1 +OCC(O)C(O)C(O)C(O)c1nnc(Nc2ccccc2)s1 +Cn1cc(C(=O)Nc2ccc3c(c2)OC(C)(C)O3)ccc1=O +O=C(Nc1cccnc1)c1ccc2c(c1)OCCO2 +O=C1c2cnc(N3CCOCC3)nc2CN1c1ccc2c(c1)OCO2 +O=C(Nc1nccs1)C1CCN(c2ncnc3[nH]cnc23)CC1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)Nc1ccccn1 +CCCCSc1nc(N)cc(N2CCN(CC(N)=O)CC2)n1 +COc1cccc(N2CCN(C(=O)c3cc(F)ccc3F)CC2)c1 +N#CCC(=O)NCc1cc(C(F)(F)F)ccc1Cl +COC(=O)c1c(NC(=O)c2cccc(C)c2)sc(C)c1C +O=c1ccccn1Cc1ncc(-c2ccccc2)o1 +COC(=O)c1ccc(NCc2cccs2)cc1O +CC(=O)c1ccc(NC(=O)NCCCn2nc(C)cc2C)cc1C +CCn1cc(NC(=O)c2cc(-c3ccccc3)[nH]n2)ccc1=O +O=C(CSc1ncccn1)c1ccc(Cl)cc1 +Cc1ccc(OCC#CCNC(=O)Cc2ccccc2Cl)cn1 +Cc1ccc(C(=O)n2ncc(C#N)c2N)cc1NC(=O)c1ccccc1 +COc1ccc(C)cc1NC(=O)NCC(=O)Nc1c(C)cccc1C +Nc1nccnc1C(=O)Nc1ccc(CC(=O)N2CCCC2)cc1 +Nc1cccc2c(OCc3ccccn3)cccc12 +CC(C)(C)C(=O)Cn1cnc2c(oc3ccccc32)c1=O +CN(CC1CCN(C(=O)OC(C)(C)C)C1)C(=O)Cc1ccsc1 +COc1ccnc(NC(=O)Cc2c(C)nc3cc(=O)[nH]n3c2C)c1 +CC(C)n1cc2cc(C(=O)NCc3cccc(F)c3)sc2c1 +Cc1ccc(S(C)(=O)=O)cc1NCc1cncs1 +Cc1ccn(Cc2ccc3c(c2)OCO3)c(=O)c1C#N +Cc1cccc(OC(=O)c2cnn(C)c2-n2cccc2)c1 +Cc1cc(NC(=O)CSc2nnc(-c3ccccc3F)n2N)no1 +O=C(Nc1ccc2c(c1)OCCO2)c1cc(-c2cccnc2)on1 +O=C(CCCc1cccs1)Nc1cccc(-c2nc[nH]n2)c1 +CNC(=O)C(C)Nc1ccnc(C(=O)N(C)C)c1 +Cc1cccc(C(C)C)c1NC(=O)Cn1cnc2cc(F)c(F)cc21 +CCc1nc(COc2cc3cnccc3cc2OC)cs1 +Cc1noc(C)c1S(=O)(=O)NCC(O)Cc1ccccc1 +COc1ccc(C#N)cc1NC(=O)N(C)Cc1ccco1 +O=C(COc1ncnc2ccccc12)NCCc1ccc(Cl)cc1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)COC3)c(C)c1O +CC(NC(=O)c1c(Br)cnn1C)C(=O)N1CCCCC1 +C=CCC1CC=CC(C)N1C(=O)COc1ccc(F)cc1 +OCC1(CNc2ncnc3c2oc2ccccc23)CC1 +O=C(CCc1ccc(Cl)cc1)Nc1cccnc1 +CC(C)(C)C(=O)N1CCN(CC(=O)Nc2nccs2)CC1 +Cc1csc(C2CCCN(C(=O)COc3cc(C)on3)C2)n1 +O=C(CSc1ncn[nH]1)NCC(=O)c1ccccc1 +CCc1cccc(OCC(=O)N2CCN(CCO)CC2)c1 +CC(C)N(CCc1nccs1)C(=O)Cc1cccc(O)c1 +O=C(c1ccn2c(-c3ccc(F)cc3)nnc2c1)N1CCCC1 +Cc1ccc(NC(=O)c2[nH]nc(C)c2Br)c(C)c1 +Cc1n[nH]c(C)c1CCC(=O)N1CCCN(c2ccc(F)cc2)CC1 +CCc1nc(CN(C)c2ncnc3c2cnn3CCC#N)cs1 +CC(Sc1nnc(N2CCOCC2)n1C)C(=O)NC(C)(C)C +CCOc1ccccc1CNC(=O)NC(C)C(C)C +COc1ccc(C(=O)c2c(N)oc3c2CCCC3)cc1 +Cc1cc(C)n2c(CN(CCC#N)CC3CC3)cnc2n1 +Cc1cc(NC(=O)CCC(=O)c2ccc3c(c2)OCCO3)ccn1 +CC1COCC(C)N1CC(=O)NC1CCC2(CC1)OCCO2 +CCCCn1ncc(-c2cccc(Cl)c2)c(CO)c1=O +Cn1c(=O)ccn(CC(=O)NCCOCC(F)(F)F)c1=O +Cc1ccc(S(=O)(=O)Nc2ccn(C)n2)cc1F +CS(=O)(=O)NC1CCN(C(=O)c2ccc[nH]2)CC1 +COc1nc(C)c(C(=O)NCc2cc(-c3ccco3)on2)s1 +O=C(Nc1cc(-c2ccccc2)on1)N1CCC(n2cncn2)CC1 +N#CCOC(=O)c1ccc(F)c(S(=O)(=O)N2CCCCC2)c1 +CC1(CCNC(=O)Nc2ccc(F)cc2C(F)(F)F)OCCO1 +Cc1cc(C)n(CCOC(=O)CCn2ncc(=O)c3ccccc32)n1 +Cc1noc(C2CCC3C(CCN3Cc3cccs3)O2)n1 +CC(C)C(Sc1ncn[nH]1)C(=O)Nc1cccc(C(F)(F)F)c1 +NC(=O)c1cc(NC(=O)c2cccc(-n3cnnn3)c2)ccc1F +Nc1nnnn1NCc1ccc(-c2ccc(Cl)cc2)o1 +COc1ccc(C(=O)N(C)C)cc1NCC(=O)Nc1ccccc1C +Nn1c(SCC(=O)Nc2ccccc2O)nnc1C1CCCCC1 +COc1ccccc1CC(=O)N(CCC#N)C(C)C +O=C1COC2(CCN(C(=O)c3ccc[nH]3)CC2)CN1CC1CC1 +O=c1[nH]c2ccccc2c(=O)n1CCc1cccs1 +CCc1nn(C)c(CC)c1S(=O)(=O)Nc1cc(C)nn1C +COc1ccc(C(C#N)CC(=O)N(C)C)cc1Cl +CCOC(=O)C1(Nc2cccc(F)c2)CCOCC1 +OCC#Cc1cccc(CSc2ncccn2)c1 +O=C(COc1ccc(F)cc1F)Nc1ccc(F)cc1F +CC1CN(CC(=O)NCC(F)(F)F)CC(C)O1 +CCc1nc2n(n1)CCCC2NC(=O)Cc1n[nH]c2ccccc12 +Cc1noc(C23COCC2CN(Cc2ccc4c(c2)OCO4)C3)n1 +Cc1sc(NC(=O)CSc2cn[nH]n2)c(C)c1C +O=C(CCc1cccs1)NCc1ccc(N2CCCC2=O)cc1 +Cc1cc(C(C)NC(=O)c2cc(F)ccc2F)c(C)s1 +COCCCC(=O)N(Cc1ccccc1)c1cccc(C)c1 +CN(C)C(CNC(=O)c1cc(=O)c2ccccc2o1)c1cccs1 +CCOc1cc2c(cc1NC(=O)c1ccc(C(N)=O)cc1)OC(C)C2 +CS(=O)(=O)N1CC(C(=O)NCC2CCCO2)Oc2ccccc21 +CC(=O)NC1CCN(C(=O)c2ccc3nc(-c4ccccc4)cn3c2)C1 +CCCS(=O)(=O)N1CCC(COCc2ccc(C#N)cc2)CC1 +CCOC(=O)C(C)Sc1nc(C2CC2)n(-c2ccccc2)n1 +CCCn1nccc1NC(=O)c1ccc(OC)nn1 +CCc1nc2cc3c(cc2n1CCCO)OCCO3 +CC(=O)Nc1cccc(C(=O)N2CCN(c3nccs3)CC2)c1 +CCOC(=O)Nc1ccc(NC(C)c2ccccn2)cc1 +Cc1nsc(C)c1NC(=O)c1nn2ccccc2c1Cl +N#Cc1cc(NC(=O)c2ccccc2SCC(N)=O)ccc1F +CC(=O)N1CCC(C(=O)N(C)c2cc(C)cc(C)c2)CC1 +CCOC(=O)c1sc(NC(=O)c2ccccc2Cl)nc1C +Clc1ccccc1C1CC(c2cccnc2)=Nc2ncnn21 +Cc1c(C2CCN(C(=O)c3n[nH]c4ccccc34)CC2)noc1N +CC(C)(C)NC(=O)c1ccccc1NC(=O)c1cccnc1 +CCOC(C)c1noc(CSc2ccc(NC(C)=O)cc2)n1 +CC(C)c1nc2cc3c(cc2n1Cc1ccc(C#N)cc1)OCCO3 +O=C(NCC#Cc1ccccc1)N1CCOCC1C1CC1 +O=C(NC1CCC(O)CC1)c1cccc(OC(F)F)c1 +COCCN(CCOC)C(=O)Nc1cccc(C)c1 +Cc1cc(C(=O)NCCNc2cn[nH]c(=O)c2Cl)nn1C +Cc1ccccc1CN(Cc1ccccn1)C(=O)CCc1ccco1 +COc1cc(C)ccc1OCC(=O)Nc1cccn(C)c1=O +COc1cc(OC)c(NC(=O)c2nccnc2CO)cc1Cl +COC(=O)c1cccc(OCCn2nnc3ccccc3c2=O)c1 +COC(=O)C(C)S(=O)(=O)Nc1ccccc1N +CCC(C)C(=O)CSc1nnc2ccc(C(F)(F)F)cn12 +COc1cc(CCNC(=O)c2ccc(CNC(C)=O)cc2)ccc1C +CCc1nc2nnc(-c3ccnc(C(C)C)n3)c(C)n2n1 +COCCn1c(C)cc2sc(C(=O)OC)c(N)c2c1=O +CCc1ccc(OC(=O)c2ccc3c(=O)n(C)c(=O)n(C)c3n2)cc1 +CCCCNC(=O)Nc1cccc(NC(=O)C(C)C)c1 +COC1CCCC1OC(=O)c1ccc(F)c(F)c1 +Cn1cnc(CNC(=O)C2CCCN(C(=O)NC3CCCC3)C2)n1 +CN(C(=O)c1cccn1C)C1CCCc2ccccc21 +CCCC(C)(CO)NC(=O)NCC1CCCC(C)C1 +CCN(CC)C(=O)CCC(=O)Nc1cccc(C(C)=O)c1 +CCNS(=O)(=O)c1cc(Br)cc2c1OCC2 +Cc1occc1-c1cc(NC2CCCOC2)n(CCO)n1 +O=C(Nc1ccccc1)N1CC(c2nc(-c3ccccc3)no2)C1 +CC(C)c1cc(C(=O)NCc2ccccc2C(F)(F)F)n(C)n1 +CCn1cnnc1SCC(=O)Nc1cc(F)ccc1F +CCN1CC(C(=O)Nc2cc(S(C)(=O)=O)ccc2F)CC1=O +CCOC1CCN(C(=O)CNC(C)=O)C1Cc1cccnc1 +Cn1cc(S(=O)(=O)N2CCN(CC(F)F)CC2)cc1C(N)=O +Cc1noc(C)c1COc1ccc(C(=O)N(C)C)cc1 +O=C(Nc1nnc(SCCc2ccccc2)s1)NC1CC1 +Cc1[nH]n(C2=NC(=O)CC(C(F)(F)F)=N2)c(=O)c1CCO +CC(C)Cn1nc(C(=O)N(C)CCC#N)c2ccccc2c1=O +Cc1nc(SCCO)[nH]c(=O)c1CCC(C)C +CNC(=O)c1ccc(C)c(NC(=O)c2ccccc2)c1 +CNc1nnc(SC(C)C(=O)N(CCC#N)c2ccccc2)s1 +Cc1ccnc2nc(C(=O)NC(C)(C)c3ccc(F)cc3Cl)nn12 +COCCNc1ncnc(Nc2nccs2)c1N +COCCN1CCN(C(=O)c2cnn(-c3ccc(F)cc3)n2)CC1=O +CCOc1ccc2nc(NC(=O)COc3nccc(C)n3)sc2c1 +OCCCCSc1nnnn1-c1ccccc1 +CCc1noc(CC)c1CNC(=O)CSc1ccccc1F +CCc1ccc(CNC(=O)NCc2cnc(C)s2)s1 +CC(C)CN(CCC#N)C(=O)c1cc(F)ccc1N +CC(C)(C)CC(C)(C)NC(=O)C1CCCN(C(N)=O)C1 +COc1ccc(NC(=O)Cc2cccc(C)c2)cc1S(N)(=O)=O +COC(=O)c1c(-c2ccccc2)noc1C=CN(C)C +C=CCOC(C)C(=O)Nc1nc(C)c(SCC#N)s1 +Cc1nc(CN2CCCC2c2nc(-c3ccccn3)no2)co1 +CCOc1ncccc1C(=O)Nc1ccnn1C(C)C +Cn1c(C(=O)OCCN2CCOC2=O)c(Cl)c2ccccc21 +COc1cc(OC)cc(C(=O)Nc2ccccc2Cl)c1 +Cc1ccc(CNC(=O)c2nnc(C)s2)c(OCc2ccco2)c1 +CNC(=O)C(C#N)Cc1c[nH]c2ccc(OC)cc12 +COc1cccc(NC(=O)CCNS(=O)(=O)c2ccccc2)c1 +O=C(Nc1cccc(-c2cn[nH]c2)c1)c1cnn(-c2ccccc2F)c1 +Cc1ccc(-n2c(SCC(=O)N(C)C)nnc2-c2ccco2)cc1 +CN(Cc1ccsc1)C(=O)Cc1ccc(N2CCCC2=O)cc1 +O=C(Nc1ccc(F)cc1OCC(F)F)c1ccncc1F +CCOc1cc2c(cc1O)C(c1cnc(C)cn1)NCC2 +CCOCCCNC(=O)C(N)c1ccc(N)cc1 +CCOc1ncccc1C(=O)NCc1ccccc1Cl +Cc1ccncc1NC(=O)NCc1nncn1-c1ccccc1 +CC(=O)c1c(F)cccc1NCCc1c(C)nn(C)c1C +CC1CCN(c2ncnc3c2[nH]c2ccccc23)CC1 +COC(=O)C1CCN(C(=O)c2cc(OC)no2)CC1 +COc1cccc(OC2CN(C(=O)c3ccnc(OC)c3)C2)c1 +O=C(Nc1nc2ccccc2s1)c1ccc(-n2ccnc2)cc1 +CC(C)c1nc(CN2CCN(C(=O)OC(C)(C)C)CC2)cs1 +CC(=O)N1CCCN(C(=O)C(c2ccccc2)c2ccccc2)CC1 +COc1ccc2cnn(CC#N)c2c1Br +Cc1cnc(NC(=O)Cn2nc3ccccn3c2=O)s1 +Cc1nn2c(CNC(=O)c3ccoc3)c(C)nc2s1 +COc1ccc2[nH]cc(C(=O)Nc3ccc(CCO)cc3)c(=O)c2c1 +Cc1cc(C(=O)N2CCCC(C)C2)c2c(C)nn(C)c2n1 +CC(C(=O)NCCc1ccccc1)N1CCOC(C(N)=O)C1 +CC(C)CCCNC(=O)Nc1ccc(F)c(C(N)=O)c1 +CC(C)(C)n1ncc2c1NC(=O)CC2c1ccc(Cl)cc1 +Cc1nc2c(NCc3cnn(C)c3)nc(N)nc2n1C +O=C(Cc1ccc(Cl)c(Cl)c1)NCc1ccoc1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)COc1ccc(F)cc1F +CC(CC(=O)NCC(=O)Nc1ccccc1)C1CC1 +Cc1ccccc1OCCNC(=O)Nc1nncs1 +COc1cc(OC)c(NC(=O)N2CCn3cccc3C2C)cc1Cl +Nc1occ(-c2ccncc2)c1C(=O)c1cccc(F)c1 +O=c1oc(-c2ccco2)nn1Cc1nccn1C(F)F +CNC(=O)C(CC(C)C)NS(=O)(=O)c1ccccc1OC +CN(C)C(=O)NCCOCc1ccc(Cl)cc1Cl +O=C1C2CC(O)CCN2C(=O)CN1CCc1ccccc1Cl +O=C(COc1ccc(Cl)cc1Cl)NCc1ccco1 +CCNC(=O)c1ccccc1SCc1c(C)noc1C +O=C(CC(F)(F)F)N(CCO)Cc1ccccc1 +CC(=O)N1c2ccccc2C2(C)CCCC(O)C12O +CCC(CC)CNC(=O)N1CCN(CCOC)C(=O)C1 +COc1cccc(OC)c1C(=O)NCc1cc(F)cc2c1OCOC2 +CC(=O)N1CC2CCC(C1)N(C(=O)Nc1cc(C)ccc1C)C2 +COC(=O)c1ccc2c(ccn2C(=O)OC(C)(C)C)c1 +CC(C)(C)C(=O)NCC1(N2CCOCC2)CCCC1 +CCC(NC(=O)c1cc(C(=O)OC)co1)c1nc2ccccc2[nH]1 +COC(=O)C1CC(O)CN1C(=O)OCc1ccccc1 +COC(=O)c1cccc(CCNC(=O)N(C)Cc2ncnn2C)c1 +Cc1ccc(CCNC(=O)c2cc3ccccn3n2)o1 +COc1cccc(-c2noc3ncnc(NCCC(C)C)c23)c1 +CC1CN(C(=O)CCNc2c(F)cc(C#N)cc2F)CC(C)O1 +CCOc1c(OC)c(Cl)cc2c1C(CCOC)NCC2 +NC(=O)c1c(NC(=O)CSc2ccccc2)sc2c1CCCC2 +Cc1cccc2nc(C(=O)NC(C)CCn3cccn3)c(F)n12 +Cc1nc2ccccc2n1CCNC(=O)c1cc2ccccc2[nH]1 +CSc1ccc(C(=O)NC(C#N)C(C)(C)C)cn1 +CC(=O)c1cc2ncc(C(=O)NC(C)c3ccccc3)cc2[nH]1 +CC(=O)N1CCC(C(=O)NCc2cccc(Br)c2)CC1 +N#Cc1noc(C(=O)Nc2ccccc2Br)c1N +CCCNC(=O)C(C)S(=O)(=O)c1nccn1-c1cccc(C)c1 +Cc1cccc(NC(=O)CSc2nnc3[nH]c(=O)c(C)c(C)n23)c1 +CCCCN(CC)C(=O)c1cnc(-c2cccs2)nc1N +Cc1cc(C)c2c(-n3c(C)ccc3C)nn(C)c2n1 +Cc1cccc(OCC(C)NC(=O)c2cc(C(N)=O)cs2)c1 +Cc1ccc(CC(C)NC(=O)NCC(C)(O)c2cnn(C)c2)c(C)c1 +CCc1cc(C#N)c(NC(=O)c2scnc2C2CC2)s1 +Cc1cccn2cc(CNC(=O)c3scnc3C3CC3)nc12 +CNC(=O)c1ccc(CN(C)C(=O)c2n[nH]c3ccc(C)cc23)cc1 +CCc1nc(C(=O)N2CCN(c3ccccc3Cl)CC2)c[nH]1 +CCCc1cc(C(=O)OCC(=O)N2CCc3sccc3C2)[nH]n1 +COCCNC(=O)N1CCC(Oc2ccc(C)nc2)CC1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)CC1OC(=O)c2ccccc21 +Cc1noc(C2CN(C(=O)c3cccc(C(F)(F)F)c3)C2)n1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)NCCC1CCCC1 +Nc1ccc(Cl)c(C(=O)NCC(=O)NC2CC2)c1 +Cc1ccc(C(=O)N2CCC3(CCC(=O)N(CC(N)=O)C3)CC2)s1 +CC(C)CCN(C(=O)C1CC(=O)N(C(C)C)C1)C1CC1 +C=CCNc1nnc(SCC(=O)c2ccc3c(c2)OCCO3)s1 +COCCCN(C)C(=O)Nc1cccc(S(N)(=O)=O)c1 +CC(C)Cc1nc(CSc2n[nH]c(=O)n2C2CC2)no1 +Cc1cc(C)c2nc3c(cc2c1)CN(Cc1ccccc1)C(=O)CO3 +CCc1nnc(-c2cc(F)ccc2Br)o1 +O=C(NCCc1nnc(-c2ccccc2)o1)c1ccccc1 +CCCOC(=O)c1ccc(NC(=O)N2CCOCC2)cc1 +CCOc1ccc(C)cc1C(O)CN1CCN(C(C)=O)CC1 +CNC(=O)c1cccc(C2CN(C(C)=O)CCN2C)c1 +CCOC(=O)c1c(C)nc(N)nc1COc1cc(C)ccc1C +CC(C)c1ccc(C(O)CNC(=O)CNC(=O)C2CC2)cc1 +Cc1ccc(C)c2c1NS(=O)(=O)c1ccccc1-2 +CN1C(=O)Cc2cc(C(O)c3ccccc3F)ccc21 +CC(C)Cn1cc(C(=O)Oc2cccnc2)c2ccccc2c1=O +CC(C)(NC(=O)C1CC(=O)N(c2cc(F)cc(F)c2)C1)C(N)=O +C=CCN(CC=C)C(=O)c1ccccc1SC(C)C +O=C(NCCC1OCCO1)C1CC(=O)N(Cc2ccccc2F)C1 +CC(=O)Nc1ccc2nc(SCC(=O)c3ccccc3)sc2c1 +Cc1cccc(C(=O)N2CC(c3nc(-c4ccccn4)no3)C2)c1 +C=C(C)CN(CC)C(=O)NCCNS(C)(=O)=O +COc1ccc(CNC(=O)NCC(C)N(C)c2ccccc2)cn1 +CCCCn1c(-c2ccccn2)nc2c1c(=O)[nH]c(=O)n2CCC +CCNS(=O)(=O)c1cccc(C(=O)NC(C)COC)c1 +Cc1c(C(=O)Nc2c(C(N)=O)oc3ccccc23)oc2ccccc12 +COc1cccc(CC2CCCN2C(=O)C2CCN(C)C(=O)C2)c1 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+CCc1nc(CNC(=O)COc2ccc(C)cc2)cs1 +CC(=O)Nc1cccc(-c2nc3ccccc3s2)c1 +COc1ccc(C(=O)NCc2ccc(N3CCCC3=O)cc2)c(O)c1 +Cc1cnn(C2CCCN(C(=O)c3cc(-c4cccs4)n[nH]3)C2)c1 +CCOc1ccc2c(C(=O)N(CC)CC)cc(=O)oc2c1 +Cc1cccnc1CN(C)Cc1cc(C(C)C)no1 +COc1ccc(C(=O)CCC(=O)Nc2cccc(C)c2)cc1 +Cc1cccc2c1C(C(O)c1ccc(O)cc1)NCC2 +CCC(C)NC(=O)c1ccc(NC(=O)c2ccc(OC)c(F)c2)cc1 +c1ccc(-c2noc(CCc3nc(CN4CCOCC4)no3)n2)cc1 +CCC(C)(O)CNC(=O)Nc1ccccc1Cn1cccn1 +CCN(C(=O)C(C)OCC(F)(F)F)c1cccc(F)c1 +COC(=O)NCCOC(=O)C(C)(C)c1ccc(Br)cc1 +CCCNc1nc(-c2cc3c(n(CC)c2=O)CCC3)cs1 +COCCOc1cccc(NC(=O)NC(C)c2ccncc2)c1 +CC(CCc1ccco1)Nc1nc(-c2ccccc2)no1 +Cc1csc(-c2ccc(CNC(=O)c3cc(C)on3)cc2)n1 +CCc1nc(NC(=O)c2ccnc(F)c2)sc1C +COc1ncccc1C(=O)N(C)Cc1cc(-c2ccncc2)no1 +CC(=O)c1ccccc1NC(=O)c1ccc(N(C)C)nc1 +COc1ccc(C(=O)N2CCc3c(nc(N)[nH]c3=O)C2)cc1 +CCCCc1c(C)nc(N2CCN(C(=O)c3ccco3)CC2)[nH]c1=O +CC(C)Cn1nc(CNC(=O)c2ccoc2)c2ccccc21 +COc1ccc(F)cc1NC(=O)c1cccnc1OCC(C)C +NC(=O)C1Cc2ccccc2N1C(=O)Nc1ccccc1 +CCc1ccccc1NC(=O)CNc1cc(OC)ccc1NC(C)=O +O=C(c1ccc[nH]c1=O)N1CCC(COc2ccccc2)CC1 +CS(=O)c1cnc2cc(C(F)(F)F)ccc2n1 +Cc1cc(C(=O)N2CCN(S(=O)(=O)N(C)C)CC2)c(C)s1 +CS(=O)(=O)c1ccc(S(=O)(=O)N2CCCC2)cn1 +COc1cc(OC)cc(C(=O)N=c2sccn2C)c1 +CCOCCNC(=O)NCCC(=O)N1CCCC1 +COc1cc(C)c(NS(=O)(=O)c2ccc(F)cc2F)cc1OC +O=C(NCc1cscn1)NC1CCN(c2ccccc2)CC1 +CS(=O)(=O)N1CCC(CNC(=O)Nc2cccc(Cl)c2)CC1 +Cc1c(-c2nnc(-c3ccccc3)o2)nnn1-c1ccccc1 +CC(C)CCNC(=O)C1CCCN(S(C)(=O)=O)C1 +CCC(C)NC(=O)C(C)NC(=O)NCc1cccc(C#N)c1 +CS(=O)c1ccc(C(=O)N(Cc2ccccc2)CC2CCC2)cc1 +COC(=O)C(Cc1c[nH]cn1)NC(=O)C1CCCCC1 +CC(=O)Nc1cc(S(=O)(=O)Nc2c(C)c(C)nn2C)ccc1F +OCCN1CCN(c2cccc(Br)c2)CC1 +FC(F)C1Cc2ccc(Br)cc2CN1 +Cc1cc(C(=O)Nc2c(C(=O)N(C)C)nn(C)c2C)nc(N(C)C)n1 +C#CCNC(=O)CNC(=O)NCc1ccc(OC2CCCCC2)cc1 +Cc1csc(N2CCCN(Cc3cnc(C4CC4)s3)CC2)n1 +Cc1cn2c(=O)c(C(=O)Nc3nc4ccccc4s3)cnc2s1 +CC(=O)N1CCC(C2NCCc3cc(C)c(F)cc32)CC1 +CNC(=O)c1ccc(NC(=O)CNc2cccc(OC(C)C)c2)cc1 +FC(F)(F)Oc1ccc(-n2ncc3c2CCNC3)cc1 +CC1COCCN1S(=O)(=O)Cc1cccc(N)c1 +CCOc1cc(C(=O)N(CC)CC)ccc1OC +CCCC1CN(C(=O)C(NC(C)=O)C(C)C)CCO1 +O=C(NCCc1cccc(F)c1)Nc1ccccc1N1CCCC1=O +O=C(NCc1cc(Cl)cc2c1OCOC2)C1CCCCC1 +O=C(c1cnn2cccnc12)N1CCn2c(nnc2C2CC2)C1 +CC(CC(O)c1ccco1)NC(=O)C1CC1C1CC1 +Cn1cnnc1-c1cncc(NC(c2ccccc2)C2CC2)c1 +CNC(=O)c1ccc(N(C)S(C)(=O)=O)c(C)c1 +OCCN(c1ncccc1Br)C1CCCCC1 +Cc1nnc2c3ccccc3nc(Nc3ccc4c(c3)OCCO4)n12 +COc1cccc(-c2nc3cc(F)c(F)cc3n2CCO)c1 +CC(=O)c1sc(CNc2c(C)cc(C)cc2C)nc1C +N#CC(C(=O)c1ccc(-n2cccc2)cc1)c1nc2ccccc2[nH]1 +CCn1cnnc1CNS(=O)(=O)c1ccc(F)c(F)c1F +COc1ccccc1CNC(=O)Cn1cc(-c2ccccc2)ncc1=O +CCOC(=O)C1CCN(C(=O)Nc2ccc(C)c3ncccc23)CC1 +Cc1noc(C)c1CC(=O)N1CCN(c2cccc(F)c2C#N)CC1 +CCOc1cc2c(cc1OC)CCNC2c1cncnc1 +C=CCNc1ncnc2c1[nH]c1ccc(OC)cc12 +Cc1cc(NC(=O)c2cc(-c3cccs3)cs2)n(C)n1 +Cn1cc(CCO)c2cccc(Br)c21 +Cc1csc(CC(=O)Cc2cccc(Br)c2)n1 +Cc1ccn2c(=NC(=O)CNC(=O)c3ccccc3)[nH]nc2c1 +Cc1ncsc1CN1CCN(c2ncccc2F)CC1 +CC(C)C1N(S(C)(=O)=O)CCN1S(=O)(=O)c1ccccc1 +Cc1cccc(C(=O)Nc2ccccc2SCC(F)(F)F)n1 +CCOc1cc(F)ccc1NCc1csc(CC)n1 +CCNC(=O)c1ccc(CNC(=O)c2cc3c(C)cc(C)cc3[nH]2)cc1 +CC(=O)NCC1CCCN(C(=O)c2scnc2C2CC2)C1 +CC(Oc1ccccc1)C(=O)NC(C(N)=O)C(C)(C)C +CC(C)N(Cc1nc2ccccc2c(=O)[nH]1)C(=O)Cc1ccccc1 +N#Cc1ccc(OCC(=O)Nc2ccc3c(c2)CCC3)cc1 +CC(O)c1cccc(NC(=O)Nc2ccc(Cl)cc2)c1 +CC(=O)c1c(C)[nH]c(-c2csc(Nc3cccnc3)n2)c1C +Cc1n[nH]c(C)c1-c1nc(Cc2ccc3c(c2)OCO3)no1 +c1cc(COCc2cncc3c2CCN(Cc2ccncc2)C3)ccn1 +C#CCOc1ccc(CCNC(=O)N(C)C(C)C)cc1 +Cn1nc(C(=O)N2CCCC2)cc1C(=O)N1CCCC1 +O=C(CCCc1ccccc1)Nc1cccn2ncnc12 +Cc1ccc(C(=O)OCC(=O)Nc2ccc(F)c(F)c2)cn1 +CCCCOCC(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +Fc1ccc(-n2cc(-c3cnccn3)cn2)c(F)c1 +CCOC(=O)CCC(=O)Nc1ccc(N2CCCC2=O)cc1 +CCOc1ccccc1N1CCN(C(C)C(C)O)CC1 +N#Cc1cccc(CN2CCCC(c3nc(-c4ccccc4)n[nH]3)C2)c1 +COc1cccc(NC(=O)CNC(=O)c2cc(C)cc(C)c2)c1 +Cc1cc2c(=O)n(CC(=O)NC(C)c3cccs3)cnc2s1 +N#Cc1ccccc1NC(=O)CCOC1CCCCC1 +CCn1nc(C(=O)Nc2c(C)nn(C)c2C)c(=O)c2ccccc21 +Cc1ccn2c(=NC(=O)CNC(=O)c3ccc(C#N)cc3)[nH]nc2c1 +CC(Oc1ccc2c(c1)CCCC2=O)c1nc(C2CC2)no1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccc(-n2cncn2)cc1 +Nc1cccc(-c2nnc(CCc3ccccc3)o2)c1 +C#CCN1CCN(CC2NC(=O)NC(C)=C2C(=O)OCC)CC1 +Nc1cc(F)ccc1NC(=O)c1cc2c(s1)CCCC2 +O=C(NC1CC1)c1ccccc1C(=O)c1ccc(F)cc1 +CC(C)c1ccccc1NC(=O)CCNS(=O)(=O)c1ccccc1 +CNC(=O)C(C)NC(=O)Nc1cc(F)ccc1OC +CNC(=O)n1nc(Sc2ccccc2)oc1=O +Cn1cnc(CNC(=O)NCCc2ccc3ccccc3c2)n1 +CCOc1c(C)cc(-c2cc(N)c(=O)n(C)n2)cc1C +O=C(NCCC1CC2CCC1C2)NCc1ccc(-c2ccn[nH]2)cc1 +CCCn1c(S(=O)(=O)Cc2ccc(F)cc2Cl)n[nH]c1=O +Cc1ccc2c(C(=O)Nc3ccncc3)nccc2c1N +Cc1cc(C)n(C(C)C(=O)N2CCc3sccc3C2)n1 +CC1CN(C(C)C(=O)Nc2ccc(Cl)cn2)CC(C)O1 +Cc1cc(C)c(CNC(=O)NC2CCN(c3cnn(C)c3)C2)c(C)c1 +CCCNc1ccc(C(=O)NCCS(N)(=O)=O)nn1 +CN(C(=O)c1cnc(C(C)(C)C)s1)C1(C#N)CCC1 +CC(OCc1ccccc1)C(=O)N1CCCC(O)C1 +CN(C(=O)CCS(=O)(=O)N1CCNCC1)c1ccccc1 +Cn1cc(CNC(=O)COCC(F)(F)F)cn1 +CCCOc1ccc(-c2cc(C#N)nn2CCO)cc1 +CCCCCC(C)(C)CNC(=O)c1c(C)c(C)nn(C)c1=O +NC(=O)COC1CCN(C(C(=O)NC2CC2)c2ccccc2)C1 +CN(C)S(=O)(=O)c1ccc(CSc2nnc(C3CC3)n2C)o1 +CNC(=O)NCCc1coc(-c2ccc(OC)cc2)n1 +CN(C)c1ccccc1Cn1cnc(C#N)c1C#N +Cc1cc(NC(=O)c2cnc(Cc3ccccc3)s2)n(C)n1 +CCc1ccccc1NC(=O)CN(C)C(=O)c1ccccc1F +CC(NCc1ccccc1S(=O)(=O)N(C)C)c1cccc(C#N)c1 +O=C(Cc1ccc(F)cc1F)Nc1cccc(C(=O)N2CCCC2)c1 +O=C(c1cc(Cl)ccc1-n1cnnn1)N1CCCCCC1 +CNC(=O)c1cccc(CNC(=O)c2c(C)nsc2NC)c1 +COc1ccc(C(O)C(C)NC(=O)COc2c(C)nn(C)c2C)cc1 +CCn1c(SCC(=O)N2CCNC(=O)C2)nnc1-c1ccccc1 +O=C(NCCC1CC2CCC1C2)c1csc(-c2ncccn2)n1 +CN(Cc1ccccc1)C(=O)CSc1ncnc2ccccc12 +CN(CCCNC(=O)c1cc(-c2ccco2)on1)S(C)(=O)=O +COc1ccc(OC)c(NC(=O)CC2C=CCC2)c1 +COc1ccc(F)cc1NC(=O)NC1CCN(C(C)C)C1=O +Cc1cc(C(=O)N2c3ccccc3CC2C)c(C)o1 +CC(C)C1C(=O)NCCN1C(=O)c1ccnc(OC2CCC2)c1 +CC(C)(C)C(NC(=O)c1cc(S(C)(=O)=O)ccc1Cl)C(N)=O +CC1Cc2ccccc2N1C(=O)NCCCn1cccn1 +Cc1cccc(-c2nnc(-c3ccc(C(=O)NCCCO)cc3)o2)c1 +CNC(=O)C(CC(C)C)NC(=O)Cn1cnc2c(C)cccc2c1=O +CCOc1ccc2c(C(=O)Nc3nccc(C)n3)cc(=O)oc2c1 +O=C(COC(=O)c1cccs1)NC1CCCC1 +CCOCCCNC(=O)c1cc2sccc2n1C(C)C +Nc1cccc(C(=O)NCc2cc(F)ccc2Br)c1 +CC(=O)N1c2ccccc2CC1C(=O)NCCc1ccc(Cl)cc1 +CC(NS(=O)(=O)c1cccc(Cl)c1)C(=O)Nc1cnn(C)c1 +Nc1cccc(OCc2cn3cccc(F)c3n2)c1 +COc1cc(OC)c(C(C#N)N(C)C(C)=O)cc1OC +CC(C(=O)Nc1ccccc1C(=O)N1CCCCC1)c1ccsc1 +COc1ccnc(N2CCN(C(=O)c3cc(CC(C)C)n[nH]3)CC2)n1 +CCc1ccc2nc(-n3ncc(C#N)c3N)sc2c1 +CC(O)(Cn1ncc2ccccc21)c1ccccc1 +CCOc1ccc(-c2nc3cccc(C)n3c2C#N)cc1 +CC(=O)NC1CCCN(C(=O)NC(C)c2ccc(C)c(F)c2)C1 +Cc1cc2c(cc1C)N(CCC#N)C(C)(C(C)C)C(=O)N2 +CN(Cc1ccncc1)S(=O)(=O)c1ccc(O)cc1 +CC(NC(=O)c1ccc(F)cc1F)c1nnc2n1CCCCC2 +Cn1cnnc1C1CCCN(c2ccc(Br)cc2C#N)C1 +CC1CCN(CC(=O)NCC(F)(F)F)c2ccccc21 +COc1ccc(C(=O)NC(C)(C)Cc2ccccc2Cl)nn1 +CC(C)NC(=O)Cn1nc(-c2ccco2)cc(N)c1=O +COC(=O)N1CCCC(C(=O)N2CCCc3c(C)ccc(OC)c32)C1 +Cc1ccsc1C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +NC(=O)c1cccc(OC(=O)C2(c3ccc(F)cc3F)CCCC2)c1 +Cn1ccnc(NC(=O)CCc2ccc(-c3ccccc3)o2)c1=O +NC(=O)c1ncc(C(F)(F)F)cc1Oc1cccnc1 +CC(C)Oc1ccc(C(=O)N2CCCC2C(=O)N2CCOCC2)cn1 +O=C(Nc1cccc(C(=O)N2CCCC2)c1)c1c(F)cccc1F +O=C(c1ccsc1)N1CCCC(c2nnc(C(F)(F)F)o2)C1 +NC(c1cc(F)cc(F)c1)c1nc2c(s1)CCC2 +O=C(OCC(=O)N1CCc2ccccc21)C1CC2CCC1O2 +CCc1nc(N2CCCCC2C)sc1C(C)=O +CCS(=O)(=O)NC(C)c1cccc(NC(=O)c2ccccc2)c1 +Cn1c2ccccc2c2cnn(CC(=O)N3CCCC3)c(=O)c21 +CC(=O)NCCNC(=O)Nc1nnc(C(C)(C)C)s1 +CN(CC(=O)OCc1ccccn1)C(=O)c1cccs1 +CNc1nnc(-c2cccn(CC(C)C)c2=O)s1 +COCCc1noc(CN(C)Cc2cnc3ccc(C#N)cn23)n1 +O=c1c2ccccc2nnn1CC(O)COc1ccc(Cl)cc1 +C=CCC1(CO)CCCN(c2cc(N)nc(N3CCOCC3)n2)C1 +COc1ccc(CCCCC(=O)N2CCOCC2)cc1 +C#CCC(OC(=O)Cn1ncc2ccccc2c1=O)c1ccccn1 +Cc1cccc(NC(=O)Cc2cccc(OCC#N)c2)c1C(N)=O +CCOc1c(OC)ccc2c1C(C1CC(=O)C1)NCC2 +Cc1cccc(NC(=O)C(C)OC(=O)c2cccc(O)c2)c1 +COCCC(=O)Nc1ccc(-c2nccs2)cc1 +CC1CCCC(C)N1C(=O)NCCc1ccc(S(N)(=O)=O)cc1 +COc1ccc(-c2[nH]nc(C)c2-c2cscn2)c(O)c1 +CCCNC(=O)Cn1nc(C(=O)Nc2ccccc2)ccc1=O +CCOc1ccc(CC(=O)Nc2nnc(-c3cc(C)nn3C)o2)cc1 +COc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)CO3)cc1 +C=CCn1c(=O)c(=O)n(CC(=O)NCCCC)c2ccccc21 +COC(=O)c1nnsc1NC(=O)c1ccco1 +COc1cccc(C(O)c2cc(F)c3c(c2)CCC(=O)N3)c1 +CC(NS(=O)(=O)C(C)C)c1ccc(OC(F)(F)F)cc1 +O=C(COc1ccc(NC(=O)c2ccco2)cc1)NC1CCCC1 +CCOC(=O)Nn1cnc2c(cnn2-c2ccc(F)cc2)c1=O +CC(C)CCN(C)C(=O)NC1CCN(C(=O)c2ccoc2)CC1 +COC(=O)NCC(=O)Nc1ccccc1C(=O)N(C)C +N#Cc1cccc(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)c1 +CC(=O)c1sc(CCN(C)c2ccccc2)nc1C +CC1CN(CC(=O)N2CCN(c3ncccn3)CC2)C(C)CO1 +COCC(=O)n1nc(-c2cccnc2)nc1NCc1cccs1 +COc1ccc(C(O)C2OC(=O)c3ccccc32)cc1 +COc1ccc(-c2nc3cc(N)cc(C)c3o2)cc1OC +Cc1cnn(CCC(=O)N2CCCc3c(C)ccc(F)c32)c1 +CCNc1nnc(-c2cnc(C(CC)CC)s2)s1 +CCNC(=O)c1ccc(C)c(NC(=O)N2CCOC(C)(C)C2)c1 +CC(NC(=O)c1ccc(N(C)C)c(F)c1)c1ccccc1 +Cc1ccccc1NC(=O)N1CCC2(CCC(=O)N(C3CC3)C2)CC1 +CN(c1ccc(C(=O)NC(C)(C)C)cc1)S(=O)(=O)c1ccccc1 +Cc1cccc(CNC(=O)c2cc(CN3CCOCC3)on2)c1 +c1ccc2nc(NCCCOC3CCCC3)cnc2c1 +Cc1occc1CN(C)C(=O)c1cccc(OCC(F)F)n1 +CCc1cc(=O)[nH]c(-c2cccc(NC(=O)C(C)C)c2)n1 +CC1=NC(=O)C(CCC(=O)Nc2cccc(C#N)c2)C(C)=N1 +CC(C)(Oc1ccc(F)cc1)C(=O)NCc1csc(=O)[nH]1 +COc1cccc(CCNC(=O)c2ccc(N)c(C)c2)c1 +COCC(=O)NCCN1CCN(c2ccccc2)CC1 +O=C(NCCOc1ccccc1Cl)c1cc2cccnn2n1 +OC(CN(Cc1ccccc1)Cc1cccnc1)c1cccs1 +CC(C)N1CC(C(=O)NCc2ncc(-c3ccccc3)[nH]2)CC1=O +O=C(CCc1nnc(-c2ccsc2)o1)OCC1CC1(Cl)Cl +COCCCOc1ccccc1NC(=O)NC1CCCC1 +COc1ccc2[nH]cc(CC(=O)C(C#N)c3nc(C)cc(C)n3)c2c1 +C=CCCCN(C)S(=O)(=O)c1ccc(C(N)=O)cc1 +O=C(Nc1cc(F)c(F)c(F)c1)c1ccc2c(c1)OCO2 +Cc1ccc2c(c1)N(Cc1ccc(F)cc1)C=NS2(=O)=O +C=CCn1c(C)nnc1SCCC(=O)Nc1ccccc1C +Nc1onc(CCc2ccccc2F)c1-c1ccccn1 +Cc1n[nH]cc1NC(=O)Cn1cc(Br)ccc1=O +Cc1cccc(C(=O)NCCNC(=O)c2ccncc2)c1 +Cc1ccccc1Oc1c(CO)c(C)nn1-c1ccccc1 +N#CC(NCc1ccccc1F)c1ccc2c(c1)OCCO2 +COC(=O)c1ccccc1COc1ccc(OC)cc1C(C)=O +Nc1ccc2c(C(=O)NCCCN3CCOCC3)nccc2c1 +COc1ccc(-c2c3c(nc4[nH]nc(N)c24)CCC3)c(OC)c1 +CCC1CCCCC1NC(=O)NCC(C)N1CCOCC1 +O=C(Nc1cccc2cccnc12)c1cc2c([nH]c1=O)CCC2 +O=C(CSc1nc(Cc2ccccc2)n[nH]1)Nc1ccccc1F +CCc1ncc(C(=O)N(Cc2sccc2C)C(C)CC)cn1 +Nc1c(Br)cc(Br)cc1CO +Cc1noc(C2CC3CN(C(=O)c4cscn4)CCC3O2)n1 +CCC(CCO)NC(=O)Nc1cccc(SC)c1 +O=C(NCc1ccco1)C1CCN(C(=O)NC2CC2)CC1 +CCOc1ccc(C(=O)NC(CC)c2ccc(Cl)cc2)cc1OC +C=CCNC(=O)C(C)N1CCN(C(=O)C(C)(C)c2ccccc2)CC1 +CNS(=O)(=O)c1ccc(C(=O)NCCCC(N)=O)o1 +CNC(=O)c1cccc(NC(=O)c2csnc2C)c1 +CCOc1ccc(OCC(=O)N(CC)CC)cc1 +Cc1nc(CN2CCOC3CN(C(=O)C4CCC4)CCC3C2)cs1 +CS(=O)(=O)N1CCC(NC(=O)c2cccc(F)c2)CC1 +CC(=O)Nc1ccc(C)cc1NC(=O)c1ccc(N2CCCC2)nc1 +C=CCN1C(=O)COC2(CCN(C(=O)c3cc(C)on3)CC2)C1C +COC(=O)CN(C)C(=O)Cc1cn2ccsc2n1 +Cc1ncc(CNc2ccc(Cl)cc2C)s1 +CCc1noc(-c2ccn3c(CC(=O)Nc4ccccc4)nnc3c2)n1 +Cc1cc(N)ccc1Nc1nc(-c2cccnc2)cs1 +CN(CCO)c1ccc2nnc(-c3ccccc3Cl)n2n1 +CCCC(C#N)NC(=O)C(C)Sc1ccc(OC)cc1 +CC(=O)NC(C)(C)c1noc(Cc2cccc(OC(C)C)c2)n1 +Cc1c(C(=O)OC2C(=O)OCC2(C)C)oc2ccccc12 +COc1cc(NC(C)=O)c(Cl)cc1C(=O)Nc1cc(C)on1 +CCCN1C(=O)CCc2cc(NC(=O)c3cccc(C#N)c3)ccc21 +NC(=O)c1cc(N)cnc1NCCc1ccsc1 +COCC1CN(C(=O)c2ccsc2)Cc2ccnn2C1 +CC(C)(C)c1nnc(CSc2nnc(C(F)(F)F)n2N)o1 +CCC(NC(=O)c1cccc(C#N)c1)c1ccc(OC)cc1 +CC1CCCC(C)N1C(=O)N1CCCC(C(=O)N2CCOCC2)C1 +CC(=O)Nc1cccc(C(=O)Nc2ncc(C)s2)c1 +C=CCNc1ncc(-c2cnccn2)c(C2CC2)n1 +CCc1ccc(C(=O)CCC(=O)NCc2ccco2)cc1 +Cc1cc(C(=O)Nc2nc3ccccc3s2)nn1C(C)C +Cc1c(Cl)cccc1NCC(=O)N1CCCC1 +C#CCNc1ccccc1C(=O)Nc1ccc(OC)cc1 +CCOC(=O)C1CCCC(=O)N1c1ccccc1C +CC(NC(=O)c1cccc(NCC(=O)N(C)C)c1)c1ccccc1 +Cc1nc(C(=O)N(C)C)ccc1C(=O)N1CCc2cc(F)ccc2C1 +CC(C)CCCNC(=O)NCc1coc(-c2cccs2)n1 +CCCCNC(=O)CNC(=O)c1ccc(C)c(C)c1 +CC1(C)CCCC1NC(=O)Nc1cccn(Cc2ccccc2)c1=O +Cc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1Cl +Nc1cc(CCCN2CCOCC2)ccc1N1CCCC1 +O=C(Cn1ncn2cccc2c1=O)NCc1ccco1 +COCCC1(O)CCN(C(=O)Cc2nonc2C)CC1C +COc1ccc(-c2nccnn2)cc1Br +CCN1C(=O)C2(CCC3CN(S(=O)(=O)C4CC4)CC32)N=C1C +CC(C)CCn1ccc(NC(=O)NCC(C)(C)c2ccncc2)n1 +Cc1ccc(-c2nnn(CC(=O)Nc3ccn(C)n3)n2)cc1 +O=C(Nc1ccncc1)NC1CCc2nnc(-c3ccccc3)n2C1 +Cc1ccc(C(=O)NCCNC(=O)c2ccc(F)cc2)cc1C +O=C(Cn1ccc(=O)[nH]c1=O)NCC1CCN(c2ccccc2)C1 +COc1ccc(NC(=O)CC(C)C)cc1S(N)(=O)=O +O=C1CC(c2nc(-c3ccncc3)no2)CN1C1CCCCCC1 +Cc1cccc(C)c1NC(=O)c1ccc2c(c1)nnn2C +Cc1cc(NC(=O)NCC2(CO)CCOCC2)c2ncccc2c1 +COc1cc(N2CCCC(N3CCCC3=O)C2)ncn1 +CCCNc1nc(-c2cccn(CC(C)C)c2=O)cs1 +COCC(C)NC(=O)N1CCCC1c1cc(OC)ccc1OC +CC(NC(=O)c1ccc(SC(F)F)cc1)C(N)=O +O=C(NCCc1ccc2c(c1)OCCO2)C1(c2ccccc2)CC1 +NC(=O)c1ccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)cc1 +CC(C)(C)NC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1cccc(-c2nccn2Cc2nc(C(C)(C)C)cs2)n1 +CCOc1cc(-c2nc(C)c(CC#N)s2)ccc1OC +CCOCCn1ccc(-c2cccc(-c3cc(N(C)C)ncn3)c2)n1 +COCC(C)NC(=O)c1cc(S(=O)(=O)N2CCCC2)cn1C +CC1(C)Cc2ccccc2-c2nc3n(c(=O)c21)CC(C#N)S3 +O=C(c1c[nH]cn1)N1CCn2c(CN3CCOCC3)nnc2C1 +NS(=O)(=O)c1ccc(CCNC(=O)c2c[nH]c3ccccc23)cc1 +Cc1ccc(CCNC(=O)c2cc(NC(=O)C3CCCC3)n(C)n2)o1 +OCCN(CCO)c1cccc(Br)c1 +CCOCC(=O)Nc1cc(-c2cc3ccccc3n2CC)n[nH]1 +COC(C)C(=O)Nc1cc(NC(=O)OC(C)(C)C)ccc1F +O=C(NCc1ccco1)C1(c2cc(-c3ccc(Cl)cc3)on2)CC1 +O=C(c1ccc2c(c1)CCC2)C1CCCN1C(=O)C1CC1 +COC(=O)c1cc(-c2cc(Cl)ccc2SC)nn1C +CCn1c(C)cc(C(=O)Cn2c(N)nc(C#N)c2C#N)c1C +Cc1ccc(C(=O)Nc2ccc(C(=O)N(C)C)cc2)o1 +O=C(CCc1ccco1)NCc1csc(C2CC2)n1 +COCCNC(=O)c1ccccc1NC(=O)c1ccccc1C +CC(C)OCCCNC(=O)c1cn(-c2ccccc2Cl)nn1 +Cc1cncc(C2CCN(C(=O)CN3CCOCC3)CC2)n1 +CCc1noc(CC)c1CC(=O)N(C)Cc1nccs1 +CCOc1cc(F)ccc1NCC(=O)N1CCc2ccccc21 +O=C(Nc1cc(-c2ccncc2)no1)c1ccc(F)cc1 +O=C(COC(=O)c1ccco1)c1ccc2ccccc2c1 +O=C(CCC1CCN(C(=O)C2CC3C=CC2C3)CC1)NC1CC1 +CCNC(=O)CN(C)C(=O)c1cccc(N(C)C)c1 +CCN(CC)C(=O)C1CCCN1C(=O)c1ccccc1F +Cc1csc(CNc2ccc(F)cc2Cl)n1 +CCC1COCCN1Cc1cnn(C(C)(C)C)c1 +NC(=O)C1CCN(C(=O)CSc2c(Cl)cccc2Cl)CC1 +CCn1cc(NS(=O)(=O)c2ccc3c(c2)CCO3)ccc1=O +O=C(C1CCOc2ccccc21)N(CC(F)(F)F)c1ccccn1 +CCc1nc2n(n1)CCCC2NC(=O)NCCC(O)c1ccccc1 +Cc1ccccc1-c1noc(CNC(=O)NCc2cccs2)n1 +CC(C)CCOC(=O)c1ccc(Cn2ccccc2=O)o1 +N#CCOc1cccc(NC(=O)NCC2CCOC2)c1 +CCCCNC(=O)C(C)Sc1nnc(-c2ccccc2)n1C +Cc1cccc(N2CCN(S(=O)(=O)Cc3ccccc3)CC2)c1 +COc1cc(C(=O)NC2CCCc3ccccc32)cc(Cl)c1OC +COc1ccc(CCc2nnc(NC(=O)C3(C)CCCO3)s2)cc1 +O=C(CN1CCOc2ccc(F)cc21)NC(C1CC1)C1CC1 +NC(=O)CCCNC(=O)c1cnc2ccccc2n1 +COc1ccnc(NC(=O)CCc2ncc(-c3ccccc3)o2)c1 +N#Cc1nnn(-c2ccccc2)c1-c1ccccc1Cl +COc1cc(C(C)=O)ccc1OC(C)C(=O)Nc1ccc(C)c(F)c1 +CC1CCN(C(=O)CNc2ccn(-c3ncccc3Cl)n2)CC1 +O=C(Cc1ccc(-n2cccc2)cc1)Nc1ccc2[nH]c(=O)[nH]c2c1 +COC(=O)c1sc(NC(=O)c2ccc[nH]2)nc1C(C)(C)C +CCOc1ccc(NC(=O)CSc2cccs2)cc1CO +CCSc1nc(C)nc2c1cnn2-c1ccccc1 +COC(=O)C(NC(=O)c1ccc(Cl)c(Cl)c1)C(C)C +Cc1nn(C)c2ncc(S(=O)(=O)N3CCCCC3C(N)=O)cc12 +O=c1[nH]nc(CSc2nnc(-c3ccccc3F)n2C2CC2)[nH]1 +Cc1cccc(N2CCN(C(=O)c3ccc(N)c(C)c3)CC2)c1 +COc1ccc(NC(=O)c2ccoc2C)cc1NC(C)=O +c1ccc(-c2noc(CN3CCc4sccc4C3)n2)nc1 +CCCN(C)C(=O)Nc1cc(C(=O)OC)ccc1OC(C)C +Cc1cc(NC(=O)C(C)Sc2nc3ccccc3s2)no1 +Cc1ccc(CC(=O)Nc2ccn(-c3ncccc3Cl)n2)s1 +CS(=O)(=O)c1ccc(Oc2ncccc2C#N)cc1 +O=C(CCSc1nnnn1CC(F)(F)F)Nc1ccccc1 +Cc1nc(CNS(=O)(=O)c2ccc(Br)cc2)cs1 +Cc1ccc(Nc2nnc(SCCS(N)(=O)=O)s2)cc1 +O=C(c1ccccc1)N1CCOC(COCc2ccccc2F)C1 +Clc1ccc(-c2nnc(CN3CCOCC3C3CC3)o2)cc1 +Cc1ccc(-n2ncc3c2ncn2nc(-c4ccccc4O)nc32)cc1 +COC(=O)C(C)NC(=O)CNC(=O)c1ccc(C(F)(F)F)cc1 +Cn1ccnc1SCc1ccc(-c2nc(-c3ccncc3)no2)o1 +C=CCNC(=O)CNC(C)c1ccc(Br)cc1 +C=CCn1c(C)nnc1SC(C)C(=O)NC1CCCCC1C +O=C(Nc1cccnc1)c1cc2occc2n1Cc1ccc(F)cc1 +CCC(C)NC(=O)c1nc(CCS(=O)(=O)c2ccccc2)no1 +O=C(CNC(=O)c1cccc2ccoc12)NCc1ccco1 +O=C(NCc1cn(-c2ccccc2)nc1-c1ccncc1)C1CCC1 +O=C(Nc1cccc(OCc2cccnc2)c1)c1ccc2cc[nH]c2c1 +CCCNC(=O)c1sc(NC(=O)C2CC2)c(C(=O)OC)c1C +O=C(CN1CCN(c2nccs2)CC1)NC1CCCCC1 +Cc1cc2c(cc(C(=O)N3CCCC3)n2CCOc2ccccc2)o1 +CCCC(CC1CCCCC1)C(=O)NCc1n[nH]c(=O)[nH]1 +COC(C(=O)N1CCCN(CC(F)(F)F)CC1)c1ccccc1 +Cc1cc(C(=O)NCC(C)c2ccc(F)cc2)on1 +CN(Cc1ccc(C(F)(F)F)cc1)CC(C#N)CCC#N +CCOC(=O)CCC(=O)NC(C)c1ccccc1Cl +O=C(CCSc1ccccc1)Nc1ccc(-n2ccnc2)cc1 +CC(C)Cc1nc2sc3c(c2c(=O)[nH]1)CC(C)(C)OC3 +CCCNC(=O)c1cnc(C2CCCCC2)nc1N +O=C(c1ccsc1)N1CCC2(CC1)CN(CCO)c1ccccc12 +NC(=O)Cc1ccc(NC(=O)c2sccc2SC(F)F)cc1 +CC1CCCC1NC(=O)NCC(O)c1ccc2ccccc2c1 +Cc1ncc(CN2CCCN(c3cccnn3)CC2)n1-c1ccccc1 +Cc1c(C(=O)Nc2cccc(C(C)O)c2)cnn1C +Cc1cc(C)c2[nH]c(CNCc3ccccn3)cc(=O)c2c1 +COc1ccc2c(CC(=O)Nc3ccc4[nH]ncc4c3)coc2c1 +CCc1ccc(OCC(=O)Nc2ccc(N)nc2C)cc1 +O=C1CC(C(=O)Nc2ccc(Oc3ccccc3Cl)cc2)CCN1 +CC(Cc1ccc(F)c(Br)c1)C(=O)Nc1nc[nH]n1 +CCOc1ccc(C(C#N)C(=O)c2ccoc2)cc1 +CC(C)CNC(=O)C(C)Nc1cccc(N2CCCC2=O)c1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2ccccc2Cl)cc1 +O=C(NCc1cccs1)C1CC(=O)N(Cc2ccncc2)C1 +COC(=O)CCN(C)C(=O)C1CC1c1ccc(Cl)cc1 +CC(NC(=O)CCCn1cccc1)c1nc2ccccc2[nH]1 +O=C(NCCNc1cnccn1)c1cc(-c2ccccc2)on1 +Cc1ccc(N2C(=O)CC(c3nc4ccccc4s3)=C2N)cc1 +O=C(COCC1CC1)NC1C2CC3CC(C2)CC1C3 +CN(Cc1ccccc1)C(=O)c1ccc2ccccc2c1 +CSc1ccc(Cl)c(C(=O)Nc2cnn(CC(F)F)c2)c1 +Cc1cc(-n2c(C)cc(C(=O)NC(C)c3ccncc3)c2C)no1 +CC(=O)OC(C(=O)Nc1cc(C)ccc1O)c1ccccc1 +Cc1ncc(CNC(=O)c2cc3cc(Cl)ccc3[nH]2)s1 +Cc1ncc(CNCc2noc(C(C)(C)C)n2)n1-c1ccccc1 +CC(C)Cn1ncc(C(=O)NC2CCC(C)CC2C)c1C1CC1 +COCC1(C(=O)NCCN2CCCOC2=O)CCC1 +COC(C)(C)c1noc(-c2cnc(Cc3ccc(F)cc3)s2)n1 +CC(C)(C)C(=O)CNC(=O)c1ccc(-n2cnnn2)cc1 +CCc1noc(CCCC(=O)Nc2nnc(C)s2)n1 +Cc1cc(C)cc(OC(=O)CC2Sc3ccccc3NC2=O)c1 +NC(=O)c1ccc(=O)n(Cc2nn(-c3ccccc3)c3c2CCC3)n1 +CCOC(=O)CCNc1ncnc2cc(Cl)ccc12 +O=C(Nc1ccc(Cl)cc1)N1CCC(n2cccc2)CC1 +COc1ccncc1NC(=O)COc1ccc(Cl)cc1 +N#Cc1ccc(Cn2cnc(NC(=O)Cc3ccc[nH]3)n2)cc1 +COc1ccc(C(O)C(=O)NC2CC2)cc1OC +CCC(CO)NC(=O)Nc1ccc2c(c1)OC(C)(C)O2 +OCCC(c1ccccc1)c1ccc2c(c1)OCCCO2 +CC(c1ccccc1)N(C)C(=O)CCn1c(=O)n(C)c2ccccc21 +Cc1nc(CSc2ccc(C(=O)NCCCO)cc2)cs1 +CCc1cccc(NC(=O)c2cccc3[nH]ncc23)c1 +COc1ccc(Cl)c2c1N(C(=O)c1cnc(C)nc1C)CCC2 +CCOc1ccc(-c2nnc(NC(=O)c3ccc(OC)cc3)o2)cc1 +COc1ccc(C(=O)Nc2nc(C)c(C)s2)cc1 +CC(NC(=O)N1CCn2cccc2C1c1ccccc1)c1ccncc1 +CCOC(=O)c1c(NC(=O)c2cnn(C)c2)sc(C)c1CC +CS(=O)(=O)N(CC(=O)NCc1ccco1)Cc1ccc(F)cc1 +O=c1c2c([nH]c3cc(-c4cccc(Cl)c4)nn13)CCC2 +CC1CCN(S(=O)(=O)c2ccc(C(=O)NCCO)cc2)CC1 +Cc1cc(S(=O)(=O)Nc2c[nH]nc2C)ccc1F +Cc1cc(NC(=O)c2cccn2C)ccc1Br +COC(=O)c1cccc(NC(=O)c2cccc(C#N)c2)c1 +Cc1[nH]nc(-c2cccc(F)c2)c1Br +Cc1oc(C(=O)N(C2CC2)C(C)C(C)C)cc1S(=O)(=O)N(C)C +CC1CC(NC(=O)C(C)Oc2ccc(F)cc2Cl)CCO1 +CSc1cccc(C(=O)Nc2nnc(-c3ccno3)o2)c1 +CCOC(=O)CN(CC1=Cc2ccccc2OC1)C1CC1 +COc1ccc2[nH]cc(C(=O)Nc3nnc(C(C)C)s3)c(=O)c2c1 +CC(=O)N1CCN(C(=O)c2oc3ccccc3c2C)CC1 +COc1ccc(C)cc1NC(=O)NC(C)C(=O)NCc1ccccc1 +CC1(NC(=O)NC(c2ccccc2)C(F)(F)F)CCOCC1 +COC(=O)C1CN(C(=O)NCc2c(C)cc(C)cc2C)CCO1 +CC(C)(C)NC(=O)Cn1c(SCC(N)=O)nc2ccccc21 +CC(=O)c1ocnc1-c1ccccc1Br +CCOc1cc(-c2n[nH]c(N)n2)cc(OCC)c1OCC +CC(=O)c1ccc(N2CCN(C(=O)c3ccc(=O)[nH]n3)CC2)cc1 +COCCNC(=O)N(C)C(C)c1cc(F)ccc1F +CC(C)Cc1nc(C(=O)OC(C)C(N)=O)cs1 +CCOc1cc(C)ccc1NC(=O)c1ccccn1 +CC(C)n1c(=O)oc2cc(NC(=O)Nc3cc(F)ccc3F)ccc21 +COc1nc(C)cc(NCCC(=O)NC2CCCCC2)n1 +CC(NC(=O)Cn1ccc(C(F)(F)F)n1)c1ccc(Cl)cc1 +Cc1ncc(CNC(=O)Nc2ccc(-c3csnn3)cc2)s1 +CCc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)cc1 +COc1ccc(N)c(C(=O)NC(C)C(=O)N(C)C)c1 +CN(C)C(=O)CNC(=O)c1ccc(Oc2ccccc2Cl)o1 +CCOc1cccn2cc(-c3cccc(N)c3)nc12 +Cc1cnc(C(NC(=O)CCC2CCCO2)C2CC2)s1 +CC(c1ccncn1)N(C)C(=O)c1cn2ccsc2n1 +N#CC(NC(=O)c1ccc(Cl)cc1)c1ccncc1 +CC1(C)Cc2cccc(OCC(=O)N3CCCCCC3)c2O1 +Cn1cnc(CNC(=O)Nc2cc(N3CCCC3=O)ccc2Cl)n1 +O=S(=O)(Nc1ccccc1CO)c1ccccc1 +Cc1ccc(CC(=O)N2CCC(C(=O)N(C)C)CC2)cc1 +CN(C)C(=O)c1cc(C(=O)c2ccccc2Cl)c[nH]1 +Cn1c(C(=O)NC2CCCCC2)nc2cc(C#N)ccc21 +CCn1c(SCC(=O)Nc2cc(C)on2)nnc1-c1ccccc1 +CC(C)(C)CN(CCCO)C(=O)Nc1ccc(F)cc1 +Cc1ccccc1C1CCCN1C(=O)c1cc(S(N)(=O)=O)c(C)o1 +Cc1cc(C)c(NC(=O)CCC(=O)c2ccc(N)cc2)c(C)c1 +COC(=O)c1cn(C2CCCCC2OC(=O)CC(C)C)nn1 +O=C(CSc1ccncc1)N1CCOCC(O)C1 +CNC(=O)c1ccccc1C#CCNC(=O)c1cc(C)cc(C)c1 +CC(Oc1ccc(C#N)cc1)c1ccnc2ncnn12 +COCC1(C(=O)NCc2cc(F)ccc2C)CCC1 +Cc1csc(NC(=O)c2csc(-c3ccco3)n2)n1 +CC1=CC(C)(C)Nc2ccc(OC(=O)c3cccnc3)cc21 +NS(=O)(=O)c1ccc(NCCCc2ccc(O)c(Cl)c2)cc1 +CCCNC(=O)C1CCCN(c2nnc3cccc(C)n23)C1 +C#CCNC(=O)c1ccc(=O)n(CC(=O)NCCC2=CCCCC2)c1 +CCOC(=O)Nc1ccc(NC(=O)OCC)cc1 +COc1cc(O)cc2c1CCNC2CCOc1ccccc1 +O=C(Nc1cccc(CN2CCCCC2=O)c1)C1CC2CCC1O2 +O=C(NCCCc1ccccn1)c1cccc(-n2cnnc2)c1 +CC(C)(C)CC(=O)NCCNC(=O)c1cccn2cncc12 +Cc1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c1 +CC(C)OCCCNC(=O)Cn1ccc2cc(Cl)ccc21 +COc1cccc(NC(=O)COC(=O)c2cccc(C(C)=O)c2)c1 +COC(=O)CCCC(=O)c1ccc(Cl)cc1Cl +Cc1cc(NC(=O)C2CCCCN2S(C)(=O)=O)n(C)n1 +Cc1ccc(C)c(CNc2ccc(CC(=O)N(C)C)cc2)c1 +Cc1nc(NC(=O)CCCc2nc3ccccc3s2)sc1C +Cc1cccc(=O)n1CCOc1ccc(Br)cc1 +Cc1cc(C)c(NC(=O)C(C)Sc2nc(C)cs2)c(C)c1 +Cc1nc(C2CCCN2C(=O)C2CCC2)cc(=O)[nH]1 +N#Cc1ccccc1Cn1nc(C2CC2)n(-c2ccccc2)c1=O +CCOC(=O)COc1cccc(NC(=O)c2sccc2C)c1 +COc1ccc(C(C)=O)cc1COC(=O)C1Cc2ccccc2O1 +CN(C)C(=O)CCNC(=O)c1ccc(C(=O)N(C)C)cc1 +COC(C)C(=O)NCC(=O)Nc1ccc(Br)cc1 +CC(C)Sc1ncnc2c1cnn2-c1ccc(F)cc1 +CC1CCC(CO)(NC(=O)Cn2ccc(N)n2)CC1 +N#CCC(=O)OCC(=O)Nc1nc2ccccc2s1 +O=C(Cn1cnc2ccccc21)N1CCCC(c2ccn[nH]2)C1 +CCc1c(C)nn(C(=O)c2ccc(NC(=O)C3CC3)cc2)c1C +CSc1ccc(C)c(C(=O)N(CCC#N)Cc2ccccn2)c1 +CCOc1ccccc1NC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +Cc1nn(C)c(C)c1NC(=O)CSc1nc(C)c(C)n1CC(C)C +CCCS(=O)(=O)NCCc1cccc(OC)c1 +C=CCOc1ccc(C(=O)Nc2nc(C)c(C)s2)cc1 +Nc1ncn(CC(=O)N2CCC3(CCCC3)CC2)n1 +CN(CCC(F)(F)F)C(=O)c1cc(F)cc2[nH]cnc12 +CC(C)N(C(=O)Cn1nc(-c2cccs2)ccc1=O)C(C)C +Cc1cc(CN(C)C(=O)Cc2cn3ccsc3n2)no1 +O=C(Cn1cnc2ccsc2c1=O)N(C1=CCCCC1)C1CC1 +CC(C)N(C)S(=O)(=O)NC(C#N)C1CCCCC1 +CC(C)(C)CCNC(=O)c1cc(S(N)(=O)=O)ccc1Cl +CCc1cc2c(N3CCN(c4ccc(O)cc4)CC3)ncnc2s1 +Cc1cc(C2CCCN2Cc2nc3cc(Cl)ccc3c(=O)[nH]2)on1 +Cc1ccc(C(O)CNC(=O)CCc2ccccc2)cc1C +COc1ccc(-c2ccc(=O)n(CCNC(=O)c3ccccc3)n2)cc1 +CN(C(=O)CN1CCOC(Cn2cccn2)C1)C1(C#N)CCCCC1 +Cc1ncsc1CCC(=O)NCc1cnn2cccnc12 +O=C(Nc1cn[nH]c1)C1(c2cccc(F)c2)CCCC1 +CC(CC1CCCC1)C(=O)N1CCN(C(=O)c2ccoc2)CC1 +CCC1CN(CCN2CCOCC2)c2ccc(F)cc2N1 +O=C1NCCCCC1Sc1nnc2c(Cl)cc(Cl)cn12 +CCc1nc2c(=O)n(CC(=O)NC3CCCCCC3)nc(C)c2s1 +O=C1C=C(N(CCO)CCO)C2(CCCCC2)O1 +NC(=O)C1CN(C(=O)c2ccc(-c3cscn3)cc2)CCO1 +COCC(=O)N1CCN(c2c(C#N)cnc3c(F)cc(F)cc23)CC1 +CS(=O)(=O)NCC1(N2CCOCC2)CCCCC1 +Nc1nc2nc3c(c(-c4ccc(O)cc4)c2c(=O)[nH]1)C(=O)CCC3 +COC(=O)C1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 +O=C1CCCCCN1CC(=O)N1CCc2ccccc21 +CNC(=O)CCNS(=O)(=O)c1c(C)noc1C +COCc1cccc(C(=O)NCCc2csc(C(C)C)n2)c1 +COC(=O)C(C)Sc1nnc2c(n1)[nH]c1ccc(C)cc12 +NC(=O)Cc1ccc(NC(=O)Cc2c(F)cccc2F)cc1 +CCc1ccccc1NC(=O)NCc1c(C)nn(CC)c1C +COc1ccc(OC)c(NC(=O)CNc2cccc(F)c2)c1 +O=C(NCC1CCCO1)c1csc(COc2ccc(F)cc2)n1 +COCc1ccccc1NCC(=O)Nc1ccc(F)cc1F +CCCNC(=O)c1cnc2scc(-c3ccccc3)n2c1=O +CSc1ccc(CN(C)C(=O)c2cn3cccnc3n2)cc1 +CC1CCCCN1C(=O)Cn1cc(C(F)(F)F)ccc1=O +CNC(=O)c1c(OC2CC2)cncc1C(F)(F)F +O=C(Nc1cccn2ncnc12)c1ccc(Cl)cc1 +CNS(=O)(=O)c1ccc(CNC(=O)c2cccc(C)n2)cc1 +COc1cccc(C(=O)OCC(=O)NCc2ccccc2C)c1 +CCOc1ccc(C(=O)NC2(C(=O)OC)CCC(CC)CC2)cn1 +COc1ccccc1-c1c(-c2ccccc2)n[nH]c1N +Cc1ccc(NC(=O)CCn2[nH]c(=O)ccc2=O)cc1C +CN(CCC(=O)N1CCN(c2ccccc2)C(=O)C1)S(C)(=O)=O +CC(NC(=O)C1CCOCC1)c1cccc(Br)c1 +CC1CN(C(=O)c2ccc(Cl)cc2Cl)CCO1 +COC(=O)C(NC(=O)c1cscn1)c1ccc(Cl)c(F)c1 +CCCn1cc(NC(=O)c2ccc(C)o2)ccc1=O +CS(=O)(=O)NCCC12CCOC1CCN(C(=O)N1CCCC1)C2 +CCc1cccc(OC(=O)CCc2c(C)nc3c(C#N)cnn3c2C)c1 +N#Cc1cccc(CNC(=O)c2ccccc2O)c1 +COCCN(C)C(=O)Nc1cccc(OC(F)(F)F)c1 +Cc1ccc(O)c(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)c1 +CCCc1nnc(NC(=O)c2cccc(N3CCCC3=O)c2)s1 +CNS(=O)(=O)c1ccc(C(=O)Nc2ccc(C)cc2OC)o1 +O=C(c1ccccc1Cl)N1CCc2ncccc2C1 +COCCNC(=O)c1c(-c2cn(C)nc2C)noc1C +COc1ccc(F)cc1NC(=O)c1cc(OC)c(C)c(OC)c1 +CNC(=O)Nc1ccc(NC(=O)c2nccnc2N)cc1 +Cc1cc(C(=O)N2CCC(C)CC2)ccc1NC(=O)c1cccn1C +O=C(NCC1CCCO1)N1CCCC1c1ccsc1 +CCOc1ccc(F)c(C(=O)N2CCCCC2C)c1F +CC(=O)Oc1ccc(C(=O)Nc2cccc(Br)c2)cc1 +COc1ccc(C(=O)NC2CCC(c3ccccc3)CC2)cn1 +CCS(=O)(=O)NCCNC(=O)NC1(c2cccc(Cl)c2)CC1 +Cc1cc(C)cc(NC(=O)C2CC(=O)N(C(C)(C)C)C2)c1 +COc1ccc(CNC(=O)NCC#Cc2ccccc2OC)cc1 +CC(C)NC(=O)C1CC2CN(Cc3cccnc3)CC1O2 +COc1cc(F)c(C(C)NC(=O)c2ccoc2C)cc1OC +COc1cc(N(C)Cc2noc(CC(C)C)n2)ncn1 +COCCn1cc(C(=O)N2CCC(c3ccccc3)CC2)ccc1=O +Cc1cccc(N2CCN(C(=O)c3cc(C4CC4)[nH]n3)CC2)c1 +Cn1cc(C(=O)NCc2ccccn2)c(=O)c2cc(Cl)ccc21 +CCC(=O)N1CCC(c2cc(Nc3nncs3)nc(C)n2)C1 +O=C(c1csc2c1CCCC2)N1CCCC(CO)C1 +CCCN(CCO)C(=O)Nc1ccccc1Br +Cc1cc(C)n(-c2ncnc(NCCN3CCOCC3)c2N)n1 +Cc1ccn2cc(C(=O)N3CCC(NS(C)(=O)=O)CC3)nc2c1 +CCOc1cc(CNc2cccc(F)c2)ccc1OC +CC(NC(=O)Nc1ccc(-c2csnn2)cc1)C1CCCO1 +CCN(CC)C(=O)CN1CCN(C(=O)NCc2ncn(C)n2)CC1 +CCC(C)NC(=O)C(C)NC(=O)c1cc(F)cc(Br)c1 +COC(=O)c1ccc(NC(=O)COC(=O)c2ccc(C)nc2)cc1 +CCN1C(=O)C(C)(C(=O)Nc2ccc(C)cc2C)Oc2cccnc21 +COC(=O)C(NC(=O)C(C)C1CC1)c1ccc(Cl)c(F)c1 +CCn1ncc(-c2ccccc2OC)c(C(C)=O)c1=O +COC(=O)c1cc(CN2CCOC(C)(C)C2)oc1C +Cc1cccc(NC(=O)Nc2ccc3[nH]c(=O)oc3c2)c1 +COc1ccc(CC(=O)N2CCN(Cc3nc(C)c(C)o3)CC2)cc1 +O=C(Nc1cc(Cl)ccc1Cl)c1cccnc1 +Cc1nccn1-c1ncccc1NC(=O)c1ccc(C(F)(F)F)cc1 +CCC(=O)c1cc2c(cc1Br)CCN2C(C)=O +O=S(=O)(c1ccc(Cl)cc1F)N1CCC(CO)CC1 +COC(=O)C1CCC(=O)N1Cc1cccc(Cl)c1 +C=CCN(CC=C)Cc1nc2ccc(OC)cc2[nH]1 +O=C(c1ccc[nH]1)N1CCC(c2nnc3ccccn23)CC1 +CC(=O)N1CCN(C(=O)CCNC(=O)N2CCCC(C)C2)CC1 +O=C(CCNC(=O)c1cccs1)NC1CCCC1 +CCCN(CC(=O)NC)C(=O)c1ccc(C)c(Br)c1 +CCOc1cc(OC)cc2c1CCNC2c1cncc(C)c1 +O=S(=O)(NCC#Cc1ccccc1Cl)c1cccnc1 +COc1ccc(CN2CCOCC2C2CC2)cc1SC +CN(C)c1nccc(NC(=O)c2ccnc(OCC(F)F)c2)n1 +Cn1c(=O)c2sccc2n2c(=O)n(Cc3ccc(Cl)cc3)nc12 +CC1c2cccn2CCN1C(=O)c1cnc(-c2ccccc2)nc1 +Cc1ccc(Br)cc1NC(=O)N(C)Cc1ccoc1C +O=C(c1ccccn1)N1CCN(S(=O)(=O)c2ccccc2)CC1 +Cc1ccc(NC(=O)N2CCC(NS(C)(=O)=O)CC2)c(Cl)c1 +Fc1ccc2[nH]c3nc(SCCc4ccccc4)nnc3c2c1 +CCS(=O)(=O)NCCCNC(=O)c1ccc(C)cc1C +COc1ccccc1CNC(=O)Cn1nc(C(F)(F)F)cc1C +Cc1n[nH]c(C)c1S(=O)(=O)N1CCN(Cc2ccco2)CC1 +CCN(CC)C(=O)C1Cc2ccccc2CN1C(=O)c1ccccc1 +O=C(NCc1cccs1)C1CC(=O)N(CCN2CCOCC2)C1 +CCOCC(O)CN1CCN(C(=O)Cc2ccc(Cl)cc2)CC1 +CCCn1cc(-c2ccnc(NCC3CCCO3)n2)c(C)n1 +Cn1cc(CN2CCc3ncnc(-c4ccc(F)cc4)c3CC2)cn1 +CC(=O)Nc1ccc(NC(=O)c2cc(=O)c3cccc(C)c3o2)cc1 +CCS(=O)(=O)N1CCc2nc(NC(=O)CC(C)C)sc2C1 +CC(C)Cc1cc(C(=O)Nc2ccc(C(N)=O)c(F)c2)[nH]n1 +COc1ccc(C(=O)NCc2cn3ccsc3n2)cc1F +Cc1noc(C)c1CCCNC(=O)NCCc1cc(F)cc(F)c1 +O=C1Nc2ccccc2CCC1S(=O)(=O)c1ccc(Cl)cc1 +O=C(Nc1nccs1)C1CCN(C(=O)c2ccc(=O)[nH]c2)CC1 +CS(=O)(=O)c1ccc(OCCCOn2nnc3ccccc32)cc1 +CCN(CC)C(=O)CCC(=O)Nc1ccccc1-n1cccn1 +CCCOc1ccc(C(=O)N2CCC(O)C2)cc1OCCC +NC(=O)c1ccc(C(=O)NCC2(c3ccccc3)CC2)cn1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCCN1CCc2ccccc21 +CCN(C)S(=O)(=O)c1c(C)nn(CC(=O)NC(C)(C)CC)c1C +O=C(Cc1csc(-c2cccnc2)n1)NCc1ccccc1F +COc1cc(=O)[nH]c(SCC(=O)C23CC4CC(CC(C4)C2)C3)n1 +Clc1cccc(NCc2noc(-c3ccoc3)n2)c1Cl +CN(C)c1nc(CNc2ccc(Cl)c(C#N)c2)ns1 +Cc1ccc2oc(C(=O)N3CCc4sccc4C3)cc(=O)c2c1 +COC(=O)C(C)NC(=O)c1cc(Cl)cn1C(C)C +COc1ccccc1N1CCN(CC(=O)NCc2ccco2)C1=O +C#CCN1CCN(C(=O)NCc2ccn(C3CCCC3)n2)CC1 +CCOC(=O)CN(C)C(=O)c1cc(Br)ccc1OCC +O=c1[nH]c(NCCOc2ccccc2)nc2ccccc12 +Cc1ccc(C2=CCN(C(=O)c3ccnc(-n4ccnc4)c3)CC2)cc1 +CC1(C)CC(NC(=O)c2coc(COc3ccccc3)n2)CCO1 +Cc1nn2c3c(cnc2c1-c1ccc(F)cc1)C(=O)CCC3 +CC(C)(C)C1CCN(S(=O)(=O)NC2CC=CC2)CC1 +CCCCCNC(=O)c1cnc(-c2cccc(F)c2)nc1N +CC(c1ccon1)N(C)C(=O)c1coc(COc2ccccc2)n1 +NC(=O)c1ccc(COC(=O)Cc2cccc(C(F)(F)F)c2)cc1 +Cc1cc(C)cc(NC(=O)COc2ccccc2CO)c1 +COc1ccc(OC)c(CN(C)C(=O)CNC(=O)c2ccoc2C)c1 +CC1(C)Oc2cc(N)ccc2N(CC(=O)N2CCCCC2)C1=O +CC(C)NC(=O)CN(C)C(=O)c1ccccc1Oc1ccccc1 +Cc1nn(C)c2nc(N(C)C(C)c3ccon3)sc12 +O=c1[nH]c2ccc(Cl)cc2c(=O)n1C1CCc2ccccc21 +O=C(CC1CCCN1c1ccc2nnnn2n1)c1ccc(F)cc1 +Cn1cc(C(=O)Nc2cc(Cl)ccc2N2CCOCC2)ccc1=O +CC(C)(C)CC(=O)N(CCC#N)CCN1CCOCC1 +O=C(Nc1cccc2scnc12)c1ccccc1 +O=C(Nc1ccc(F)cc1)c1ccc(OCC2CCCO2)cc1 +Nc1ccc(F)c(C(=O)Nc2cc(Cl)ccc2Cl)c1 +NC(=O)CN1CCN(c2ccc3cccc(Br)c3n2)CC1 +CCn1nc(C)c(Cl)c1C(=O)Nc1ccccc1C +CCOc1ccc(C(C)NC(=O)N2CCC(C(N)=O)CC2)cc1OC +Cc1ccncc1NC(=O)c1cc(Br)cnc1N +Cc1cc(C)cc(N(C)C(=O)CN(C)C(=O)c2cccs2)c1 +Cn1ccc2c(NC(=O)C3CC(=O)N(Cc4ccccc4)C3)cccc21 +CN(C)c1nc(CNc2cccc(C(=O)N3CCCC3)c2)ns1 +Nc1cc(NC(=O)COCc2ccco2)ccc1Cl +CN(Cc1ccncc1)S(=O)(=O)c1ccc(F)cc1 +O=C(NCC1OCCc2cn(CC3CC3)nc21)c1ccncc1 +CCOC(=O)C1CCN(C(=O)Cc2c(C)n[nH]c2C)CC1 +COC(=O)c1ccc(CN(C)Cc2cnc3ccc(C#N)cn23)cc1 +CC1CCCC(CNC(=O)c2ccc(OCC(N)=O)cc2)C1 +CN1CCOc2ccc(NC(=O)c3ccc(F)cc3Cl)cc2C1=O +COc1ncccc1CN1CC(N2CCOCC2)C2OCCCC21 +CC(NC(=O)Cn1ccnc1-c1ccccc1)c1ccccn1 +CN(C(=O)CN1CCc2ccccc21)c1ccccc1 +Cc1nc(Nc2ccccc2)cc(C2CCN2C(=O)c2cnn(C)c2)n1 +CCn1c(SCC(=O)NC2CCCCC2)nnc1C1CC1 +CC(=O)c1ccc(NC(=O)NCc2ccccn2)cc1C +COc1cc(NC(=O)CNC(=O)c2cccc(Cl)c2)cc(OC)c1 +c1nc(SCc2ccc3c(c2)OCO3)c2ccsc2n1 +COc1ccc(-n2nnc(C(=O)Nc3nccs3)c2C)cc1 +Cc1cc(C)cc(NC(=O)C(C)Sc2nnnn2C(C)C)c1 +Cc1nc(C2CC2)nc2sc(C(=O)NC3CCC(O)CC3)c(C)c12 +CC(=O)N(C)C1CCN(C(=O)c2ccc(F)cc2Cl)CC1 +CCCC(C)N1CC(C(=O)Nc2c(C)noc2CC)CC1=O +Cc1cccc(CN2CCc3nc(C)[nH]c(=O)c3CC2)c1 +COc1ccccc1-c1cccc(C(=O)NC2COCC2OC)c1 +COC(=O)C1CCCCN1S(=O)(=O)c1ccc(C)cc1 +NC(=O)Cc1ccc(NC(=O)NCc2cc[nH]n2)cc1 +Cc1cc(C)cc(N(C)C(=O)C2CCCN2C(=O)c2ccco2)c1 +Cc1csc(CN(C)Cc2ncccc2C(F)(F)F)n1 +O=C(NCCc1ccccc1)NCc1nnnn1-c1ccccc1 +COc1ccc(C)cc1C(=O)CCCC(=O)N1CCCC1 +CCS(=O)(=O)N1CCc2c(cccc2NS(C)(=O)=O)C1 +O=C(CCn1ccccc1=O)NCCCN1CCCC1=O +Cc1c(-c2noc(-c3cccnc3)n2)nnn1Cc1ccccc1 +Cc1ccc(Cl)cc1NCC(O)c1ccccn1 +Cc1nc2ccccc2nc1-c1ncnc(N)c1C#N +COc1ccc2cc(C(=O)Oc3ccccc3)c(=O)oc2c1 +Cc1ccc(CC(=O)Nc2ccc(Cl)cc2)cn1 +Cc1ccoc1C(=O)Nc1ccc(Cl)c(S(N)(=O)=O)c1 +COCC(O)CN(C)S(=O)(=O)c1cn(C)nc1N +COC(=O)C1CCCN1C(=O)c1ccc(-c2ccc(F)cc2)o1 +CCC(OC)C(=O)Nc1cnc2c(c1)c(C)nn2C +Cc1ccc(F)cc1CNCC(O)c1ccccc1 +CC(Oc1ccccc1)C(=O)NCc1nn(C)c2c1COCC2 +CC(C)CNC(=O)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1cc(C)cc(C(=O)NCC(C)(C)c2ccncc2)c1 +CC(C)Cn1c(=O)[nH]c2c(c1=O)C(C)(C)Cc1ccccc1-2 +CCc1nc(CC(=O)NCc2cccc(F)c2)cs1 +Cc1ccccc1-c1nnc(N(C)C(=O)C2CC2)s1 +CCNc1nnc(S(=O)(=O)CCc2ccccc2)s1 +Cc1ccc(NCc2ccc(C#N)cc2F)c(O)c1 +COC(=O)C(NC(=O)CCc1ccc(F)cc1)C(C)C +Cc1cc(C(=O)NCC2CCCC2)nc(N2CCCC2)n1 +Cc1cc(NC(=O)CC(C)(C)C)ccc1N1CCCCC1=O +CC(=O)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1N(C)C +CCOCCN(CC)S(=O)(=O)c1ccc(N)nc1 +CC(C)CC(C)OCCC(=O)Nc1ccc2nc[nH]c(=O)c2c1 +CCC(C)n1nccc1NC(=O)c1nc(C(C)C)cs1 +COc1ccc(Cl)cc1NC(=O)C(OC)c1ccccc1 +Nc1c(NCc2ccco2)ncnc1-n1nnc2ccccc21 +CCC(C)C(=O)CSc1nnc(C)n1-c1cccc(NC(C)=O)c1 +CCN(CC)C(=O)c1ccnc(C(=O)N(CC)CC)c1 +Cc1csc(N2CCN(C(=O)c3cccc(C)c3O)CC2)n1 +Cc1ccc(C)c2sc(NC(=O)c3ccn(C)n3)nc12 +Cc1ccccc1SCC(=O)Nc1cc(C2CCOCC2)[nH]n1 +CS(=O)(=O)NCC(=O)N1CC2CC3CC(C2)CC1C3 +CC(Cn1cccn1)NC(=O)NCCN1CCCCCC1=O +C=CCc1ccc(OCC(=O)Nc2ccnc3ccnn23)c(OC)c1 +COc1ccc(CCNC(=O)C2(C#N)CCCC2)cc1OC +Cc1cc(Cl)ccc1NC(=O)NCCNC(=O)c1ccco1 +Cc1cc(-n2cc(F)c(=O)[nH]c2=O)nc(-c2ccccc2)n1 +C=CCNS(=O)(=O)c1cc(NC(C)=O)ccc1C +Cc1nnc(N2CCCN(c3ccccc3C#N)CC2)c(C#N)c1C +FC(F)(F)Cn1cc(NCc2ccccc2Br)cn1 +O=C(Cc1noc2ccccc12)NCCc1ccncc1 +CCCOc1nc(N)nc2c1-c1ccccc1CC2 +COc1ccc(CNC(=O)Nc2cccc(N3CCOC3=O)c2)cc1 +Cc1nnc(SCC(=O)NC(C)(C#N)C2CC2)n1N +COc1ccnc(NC2CCc3nc(C)nn3C2)n1 +O=C(OCc1nc(-c2cccs2)no1)c1ccncc1 +Cc1ccc(C(=O)NCCNC(=O)c2ccc3cc[nH]c3c2)cc1F +CN(c1cccc(F)c1)S(=O)(=O)Cc1noc2ccccc12 +CCc1nc(CC(=O)N(C)CCc2ccc(F)cc2)cs1 +Cc1n[nH]c(C)c1CCc1cc(=O)n2nc(C)c(-c3ccccc3)c2[nH]1 +Cc1nc2ccc(C(=O)N3CCCC3c3cnn(C)c3)cc2nc1C +Cn1cnc(CNC(=O)NC(Cc2ccccc2)C2CC2)n1 +C=CCNC(=O)C(C)N1CCN(C(=O)COc2ccc(F)cc2)CC1 +CCCNC(=O)CNC(=O)c1ccc2c(c1)Cc1ccccc1-2 +CCOc1ccc(NC(=O)Cn2nnc(-c3ccccc3)n2)c(C)c1 +COC(=O)c1cc(Br)c2c(c1)C=CCO2 +O=C(Nc1nnc(Cc2nc3ccccc3[nH]2)s1)c1ccccc1 +COC(=O)C1=C(C)NC(=O)NC1c1ccccc1F +CN(CC(=O)NCC(O)c1cccc(F)c1)C(=O)OC(C)(C)C +Cc1ccc(CC(=O)Nc2ccc(CC(N)=O)cc2)cn1 +COc1cccc(NC(=O)N2CCN(Cc3ccc(C)cc3)CC2)c1 +CC(=O)Oc1cc(=O)n(C)c2cc(C)n(C)c(=O)c12 +Cc1ccccc1NC(=O)Cc1ccc(S(=O)(=O)C(C)C)cc1 +Cc1ccc(NC(=O)c2ccccc2NS(C)(=O)=O)cc1Cl +COc1ccc(CNS(=O)(=O)c2cc(F)cc(F)c2)cc1 +C#CC(CC)(CC)NC(=O)CSc1ncccc1Cl +CNC(=O)CSc1nc2ccccc2c(=O)n1-c1ccccc1F +COc1ccc2c(c1)CC(NC(=O)NCc1ccco1)CO2 +c1ccc(OCc2nc(-c3cccnc3)no2)cc1 +CN(Cc1ccsc1)C(=O)CCCc1cc(F)ccc1F +O=C(Cn1cnc2ccc(Cl)cc2c1=O)Nc1ccc(F)cc1 +COC(=O)C1=C(C)N(CCc2ccc(OC)c(OC)c2)C(=O)C1 +Cn1nccc1-c1nn2c(-c3ccsc3)nnc2s1 +CCC(=O)N1c2ccccc2CC1C(=O)N1CCN(CC)CC1 +CCNC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(F)cc1 +Cc1cc(S(=O)(=O)N2CCOCC2C2CC2)c(F)cc1F +CC1CN(C(=O)NCCc2ccc(F)cc2)CCO1 +Cc1noc(C2CN(C(=O)c3ccc(C(C)(C)C)cc3)C2)n1 +CC(C)CNc1nc(-c2ccc(C(C)C)[nH]c2=O)cs1 +CC(C)(C)C(=O)COC(=O)Cn1ccc2ccccc21 +O=c1oc2c(Br)c(O)c(Br)cc2s1 +Nc1ccc2nc(CC(=O)n3cnc4ccccc43)oc2c1 +CCNS(=O)(=O)c1ccc(OC)c(C(=O)Nc2cccc(C)c2)c1 +CC(C)CCN(C)C(=O)Nc1ccc(C(=O)NC2CCOCC2)cc1 +COc1cccc2ccn(CC(=O)NC(C)c3ccccc3)c12 +Cc1cc(C(C)Nc2cccc(F)c2N)c(C)s1 +CCOCCCNC(=O)Cn1cc(Br)ccc1=O +Cc1ccc(CNS(=O)(=O)c2cc3n(c2)CCCNC3=O)cc1 +O=C(Cn1cc(-c2ccccc2)cn1)n1ccnc1 +CCCN1CCOc2cc(C(=O)c3ccc(N)cc3)ccc21 +CCOCCCNC(=O)c1cc(SC)ccc1C +COc1cc(C)c(NC(=O)CNC(=O)c2ccccc2C)cc1OC +Cc1nc(CN2CCCN(c3ccccc3C)CC2)co1 +COc1ccc(C(=O)N(C)c2ccc(C)cc2)cc1-n1cnnn1 +CC(C)c1nnc(NC(=O)C(C)c2ccsc2)s1 +CC(C)(C)OC(=O)C1CCCN1Cc1ccn[nH]1 +COc1cc(Br)c(CNCCC(F)(F)F)cc1OC +O=C(COc1ccccc1F)Nc1nc2c(s1)COCC2 +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)CCNC(=O)C(C)(C)C +Cc1ccc(C(=O)NCCNC(=O)c2cccnc2)c(=O)[nH]1 +c1cnc(N2CCC3C2CCN3Cc2ccoc2)nc1 +CSc1ccsc1C(=O)N1CCC(C(N)=O)c2ccccc21 +CNC(=O)Nc1cccc(NC(=O)c2csc(C)n2)c1 +NC(=O)c1ccc(Cl)cc1NC(=O)c1ccnc(-n2cncn2)c1 +CC(NC(=O)c1ccoc1)c1ccc(-n2ccnn2)cc1 +O=c1c2cccc(F)c2ncn1CC(O)c1cccnc1 +O=C1CCc2cc(C(=O)NCc3nc4ccccc4s3)ccc2N1 +CC1Cc2c(sc3nc(-c4ccco4)nn23)CN1 +Cc1cccc(CC(=O)N(Cc2cnc3ccccn23)C2CC2)c1 +CC(C)(CNC(=O)CN1CCOc2ccccc21)N1CCOCC1 +COC(=O)c1ccc(C(=O)N2c3ccccc3CC2C)s1 +CCOc1ccc(CC(=O)N(C)Cc2csc(C)n2)cc1 +CCOC(=O)c1cccc2[nH]c(-c3cccc(N)c3)nc12 +O=C(NC1CC1)C1CCN(c2ncnc3[nH]ncc23)CC1 +CCS(=O)(=O)N(C)CCCNC(=O)c1cn(C)c2ccccc12 +CC(C)CCNC(=O)Nc1ccc(-n2cncn2)nc1 +NC(=O)Cc1ccccc1NC(=O)NCc1ccco1 +CNC(=O)NCC(=O)Nc1cc(-c2cc(Cl)cc(Cl)c2)[nH]n1 +CCOc1ccc(C(=O)N2CCN(Cc3nc(C)cs3)CC2)cc1 +COC(=O)c1sc(COc2ccccc2OC)nc1C +Nc1ccnn1C(c1ccccc1)c1ccc(F)cc1 +CC(=O)NC(C(=O)Nc1ccc2c(c1)OCO2)C(C)C +COCCCCNC(=O)c1cc(NC(C)=O)ccc1O +NC(=O)c1ccc(OCC(=O)NC2c3ccccc3CC2O)cc1 +Cc1ccc(C(=O)N2CCN(C(=O)NCc3ccco3)CC2)cc1F +C=CCOC1CCN(C(=O)Cc2ccccn2)C1Cc1cccnc1 +CCn1nnc(NC(=O)c2ccc(C)cc2Cl)n1 +CC(C)C(C)(C#N)NC(=O)Cn1cc(C(F)(F)F)ccc1=O +Cc1nc(CN2CCOC3C(Oc4cccnc4)CCC32)cs1 +Cc1cnc(C(=O)N2CCCC2)c2cccc(N)c12 +Cc1ccc(OCC(=O)N2CC(C)OCC2(C)C)cc1 +CC(CNC(=O)CCn1cncn1)c1nc(-c2ccccc2)no1 +Clc1ccc2[nH]c(-c3cncc(N4CCOCC4)n3)nc2c1 +CCCc1cc(C(=O)NCc2nncn2CCC)[nH]n1 +COCC(C)N1CCN(C(=O)C(C)NC(=O)Nc2ccccc2)CC1 +O=C(Cc1csc(-c2ncccn2)n1)Nc1ccc2cn[nH]c2c1 +COCc1ccc(NCC2CCN(c3cccc(O)c3)C2)cc1 +OC(CNc1ccc(F)c(Cl)c1)c1ccccn1 +O=c1nc(NCCO)c(SCc2ccccc2)n[nH]1 +O=C(NCC(c1ccccc1Cl)N1CCOCC1)C1CCCO1 +COc1ccc(C(C)C)cc1-c1cc(N)nc(C)n1 +O=C(Nc1nc2c(s1)CCC2)c1ccnc(F)c1 +CC(C)Cn1ncc(C(=O)N(C)c2ccc(Cl)cn2)c1C(F)F +CCOC(=O)CN(C(=O)Cc1csc(C)n1)C(C)C +CCC(=O)NCC(=O)N1CCC(OCc2ccccc2F)CC1 +COc1ncccc1C(=O)N1CC2CC(c3nc(C)no3)OC2C1 +O=C(Cn1nc(C2CC2)cc1C(=O)N1CCCC1)Nc1ccccc1 +COc1cc(CNc2c(C)cccc2O)ccc1F +CCCc1cc(NC(=O)C2CCN(C(=O)C3CC3)CC2)n[nH]1 +Cc1cc(NC(=O)CSc2nnc(-c3cc(C)on3)o2)no1 +CNC(=O)c1cccc(CCNC(=O)Cc2c[nH]c3c(C)cccc23)c1 +COC(=O)Cn1c(-c2ccc(N)cc2)nc2ccccc21 +CCC(CO)NC(=O)NCc1cccc(C(N)=O)c1 +Cc1nc(C)n(C2CCCN(C(=O)CN(C)S(C)(=O)=O)C2)n1 +COc1ccccc1COC(=O)C(C)NC(=O)c1cccs1 +Cn1ncnc1-c1ccnc(NCCc2nc(-c3ccccn3)no2)n1 +Cc1nnc(C2CCCN2C(=O)CCc2cccc(F)c2)o1 +COc1ccc2nc(C(=O)N(C)CCc3ccc(F)cc3)ccc2c1 +Cc1ccc(N(C)C(=O)c2cccn2Cc2noc(C3CC3)n2)cc1 +O=C1CN(c2ncnc3[nH]cnc23)CCN1C1CC1 +CC1C(=O)Nc2ccc(-c3csc(-c4ccccn4)n3)cc21 +CCOC(=O)c1sc(N(C(=O)c2ccnc(F)c2)C2CC2)nc1C +CC1CN(CCNc2ccccc2F)CC(C)O1 +Cc1ccc(CCCC(=O)Nc2sc(C)c(C)c2C(N)=O)cc1 +CC(=O)N1CCN(C(=O)CNc2cccc(Cl)c2Cl)CC1 +Cc1ccc(C(=O)NCCNC(=O)Nc2cccnc2)cc1 +CCC(=O)N1CCN(c2ccc(Nc3ccc(C)cc3)nn2)CC1 +O=C(Nc1ccncc1)c1ccc(N2CCCCCC2)nc1 +C=CCNC(=O)Nc1ccc(NC(=O)c2cnn(CC)c2)cc1 +COc1cc(C)c(S(=O)(=O)Oc2ccccn2)cc1C +Cc1cc(-c2nnc(Nc3ccccc3)s2)no1 +CCc1cccc(NC(=O)c2cn(CC)c3nc(C)ccc3c2=O)c1 +CC1COCC(C)N1C(=O)c1ccc2c(c1)nnn2C +CCCN(CC(=O)NC)C(=O)c1c[nH]cc1-c1cccc(OC)c1 +CN(CC1CC1)C(=O)c1cc(OCc2ccccc2)n(C)n1 +Cc1cc(C)nc(NC(=O)C2CN(C(=O)c3cnccn3)C2)n1 +CC(C)Cn1c(CCCNC(=O)C(C)C)nc2ccccc21 +Cc1ccc(NC(=O)N2CC(C)OC(C)C2)cc1Br +O=C(NC1CC(=O)N(C2CC2)C1)c1cncc(Br)c1 +COc1cc(OC)cc(-c2n[nH]c3ncnc(N)c23)c1 +Cc1ccc(S(=O)(=O)NC(CC(C)C)C(N)=O)cc1 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc[nH]n3)ccc21 +Cc1noc(C)c1CC(C)NC(=O)NCc1ccc(Cl)cc1 +COCC(C)(O)CNS(=O)(=O)c1ccc(F)c(C)c1 +Cc1ccc2nc(CN3CCOC(C(F)(F)F)C3)[nH]c2c1C +CCOc1ccc(NC(=O)C2CC(=O)Nc3ccccc32)c(C)c1 +COc1ccc(CN(C)C(=O)CCNC(C)=O)cc1F +Cc1ccc(C(=O)NCCc2ccccn2)cc1F +O=C(NCc1ccncc1)c1cc2c(s1)-c1ccccc1CC2 +O=C1CCC(C(=O)N2CCCC2c2noc(C3CC3)n2)N1 +CC(C)n1nccc1NC(=O)N1CCCCCC1 +OCc1nnn(-c2ccccc2)c1Cc1c[nH]c2ccccc12 +O=C(CCC(=O)c1ccc2c(c1)CCC2)Nc1ccccc1 +COc1ccccc1CNS(=O)(=O)c1cc(F)cc(F)c1 +Cc1nc(-c2nc[nH]n2)sc1C(=O)OCCc1cccs1 +Cc1cc(C)nc(NCc2cc3ccccc3o2)n1 +COCCNc1nccc2c(N)ccc(Cl)c12 +CC1(C)COC(=O)C1OC(=O)CCC1CCCO1 +CC(C)NC(=O)Cn1cc(C(=O)c2ccccc2)c2ccccc21 +Cc1cccc(C2CC2C(=O)N2CCN(Cc3ccccn3)CC2)c1 +CC(C)=CC1C(C(=O)Nc2ccc(OCC(N)=O)cc2)C1(C)C +CC(CNC(=O)NCc1nc2ccccc2s1)N1CCOCC1 +Cc1cncc(-c2ccc(CC(=O)N(C)C)cc2)c1 +Cc1ccc(C(C)NC(=O)N(C)CCc2ccccn2)o1 +C=CCNC(=O)C1CC(=O)N(c2ccc(Br)cc2)C1 +CCn1nc(-c2cc(F)ccc2OC)cc(N)c1=O +Cc1ccc(S(=O)(=O)c2c(C)cc(C)nc2N2CCOCC2)cc1 +O=C(NCc1ccc(Cl)cc1)c1cc(Cl)ccn1 +CCC(C)n1nc(C(C)C)c2cnn(C(C)(C)C)c2c1=O +CC(C)c1nc(CNc2cccc(Cl)c2C(N)=O)no1 +CC(=O)N1CCN(C(=O)C(C)Sc2cccc(F)c2)CC1 +COC(=O)CCC(=O)c1cc(OC)ccc1Cl +CNc1ccc(C(=O)Nc2ccc(F)c(F)c2)cn1 +Cn1cc(C(=O)NCc2ccc(OCC3CC3)nc2)c(C(C)(C)C)n1 +COCCn1ccc2cc(NC(=O)NCCC(F)(F)F)ccc21 +C#CCCN1CCN(C(=O)c2ccc(-n3ccnn3)cc2)CC1 +CCOc1cc2c(cc1CNC(=O)c1csc(C)n1)OC(C)C2 +CC(=O)c1ccc(OC(=O)c2cccnc2OCC(F)(F)F)cc1 +CC(=O)c1cccc(NC(=O)Cc2ccccc2N)c1 +CN(Cc1cccc(Cl)c1)c1ncc(CO)s1 +CCC(COC)NC(=O)C1CC(=O)N(C2CCCCCC2)C1 +Cc1ccc(-c2nc(NC3CCCC3)ncc2-c2ccncc2)cn1 +O=c1[nH]c2ccsc2c(=O)n1C1CCCCCC1 +O=C(NC1CC1)C(O)c1ccc(Oc2ccccc2)cc1 +COc1c(C)cnc(CNC(=O)NCCCc2cn[nH]c2C)c1C +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccc(OC(F)F)cc1 +CN(Cc1cccc(C#N)c1)C(=O)c1cc(=O)[nH]c2ccccc12 +O=C(Nc1nc[nH]n1)c1cccc(-n2cccc2)c1 +CCOCC1CN(C(=O)c2ccc3c(c2)OCO3)Cc2cncn2C1 +Cc1occc1S(=O)(=O)Cc1cccc2ccccc12 +O=C(CC1C(=O)Nc2ccccc21)Nc1ccc(F)c(Cl)c1 +CC(C)(C)c1ncc(NC(=O)c2sccc2C2CC2)cn1 +Cc1ccccc1OCC(=O)Nc1ccc(Br)c(C)n1 +Cc1nc(Nc2ccccn2)sc1C(=O)NC1CCC(C)CC1 +Cc1cc(NC(=O)CSc2ccc(-c3ccccn3)nn2)no1 +CC(=O)Nc1nc(COC(=O)c2cccc(F)c2)cs1 +CC1CC1NC(=O)c1ccc(S(N)(=O)=O)cc1 +CC(Sc1nnc(Cc2cccs2)n1C1CC1)C(=O)N(C)C +Cc1cc(C)n(C(C)C(=O)NCC(C)Oc2ccccc2)n1 +CCc1cc(C(=O)N2CCCCCC2c2ccco2)no1 +CS(=O)c1ccc(C(=O)OC2CCOC2=O)cc1 +Cc1cc(NC(=O)NC2C3CCC(C3)C2CO)c2ncccc2c1 +Cc1ccccc1C(=O)c1cccn1CC(=O)NCc1cccnc1 +CCS(=O)(=O)c1ccc(NC(=O)OCc2ccccc2)cc1 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(F)cc1 +COc1cc(Cl)ccc1C(=O)NCCS(=O)c1ccccc1 +CCCC(NC(=O)c1cccc(N)c1)c1cccs1 +O=C(Nc1cccc(-c2ccn[nH]2)c1)c1ccc2[nH]cnc2c1 +O=C(c1ccc(Br)cc1)N1CCc2ccccc2C1 +O=C(CSc1ncnc2nc[nH]c12)N1CCCCC1 +CC(=O)Nc1sc(F)cc1C(=O)c1ccccc1Cl +N#Cc1cccc2nc(-c3ccccc3C(F)(F)F)nn12 +O=C(COC(=O)c1ccccc1C(F)(F)F)NCC1CCCO1 +CC(c1cc(F)ccc1F)N(C)C(=O)CCCCNC(N)=O +Cc1ccc(NC(=O)NC(C)(CO)C2CC2)c(OCC(F)(F)F)c1 +O=C(NCCNS(=O)(=O)c1cccs1)c1ccc(F)cc1F +O=C(NC1CC1)c1cccc(OC(=O)c2cnn(-c3ccccc3)n2)c1 +Cn1c(=O)c2[nH]c(CCNC(=O)C(C)(C)C)nc2n(C)c1=O +CNS(=O)(=O)c1ccc2c(c1)N(C)CC(C)(C)O2 +COc1cc(CN2CCOC3CCCCC32)cc(OC)c1 +CC(C)N(C(=O)Cc1ccc(S(=O)(=O)C(F)F)cc1)C1CCC1 +Cc1cccc(-c2nc(CNC(=O)C3CCCC3)no2)c1 +CCOc1ccc(C(=O)N2CCN(c3nccn3C)CC2)cc1 +Cc1cc(=O)c(CC#N)nn1-c1ccc(Cl)c(Cl)c1 +Cc1cccc(-n2nnnc2SCCOC(C)C)c1 +COc1ccc(C(=O)c2nnc3nc(C(F)(F)F)nn3c2C)cc1 +CCCc1cc(C(=O)Nc2cccc(C)c2C(N)=O)sc1C +Cn1cnc(S(=O)(=O)NCC(C)(O)C2CC2)c1 +COC(=O)c1ncn(Cc2ccccc2OC(F)F)n1 +Cc1ccc(N2CCC(C(=O)NCC(C)Cn3cccn3)C2=O)cc1 +COc1ccccc1NC(=O)CCn1c(=O)oc2ccc(Cl)cc21 +Cc1nnc(SC2COC(=O)C2)n1-c1ccccc1 +Cc1ccc(C)c(C(=O)CCC(=O)Nc2ccc3c(c2)OCCO3)c1 +CC(C(=O)Nc1cnn(CC2CC2)c1)n1ccc(C(F)(F)F)n1 +CC(C)(C)OC(=O)NCC1NCCc2cccc(F)c21 +CC(=O)NCc1ccc(NC(=O)c2ccco2)cc1 +CCc1nn(CCC(=O)OC)c(=O)c2cc(C)nn12 +COCc1ccccc1NCC(=O)Nc1cccc(C(C)=O)c1 +Cc1csc(C(=O)NCC(C)(O)c2cccs2)c1 +CN(Cc1ccccc1)C(=O)CNC(=O)c1cc2cn[nH]c2cn1 +CCNC(=O)CN(CC)C(=O)c1ccc(Oc2ccccc2)cc1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NCc2ccc(C#N)cc2)[nH]n1 +N#Cc1ccccc1CN1CCN(C(=O)C2CC2)CC1 +CC(NC(=O)Cc1csc(-c2ccccn2)n1)C(=O)NC(C)(C)C +CCC(C)n1ncc(C(=O)NCC2(C)CCCO2)c1C1CC1 +O=S(=O)(NCC1CCN(S(=O)(=O)C2CC2)CC1)C1CC1 +CC(=O)Nc1ccc(OCC(=O)N(C)C(C)c2ccccc2)cc1 +CC(=O)NC(CC(=O)Nc1ccnn1CC(C)C)c1ccc(C)cc1 +CCc1nn2c(CO)c(-c3ccc(Cl)cc3)nc2s1 +Nc1nc(COC(=O)Cc2ccccc2)nc2ccccc12 +COc1cccc(Oc2ccc(C(C)=O)cc2N)c1OC +CC(Oc1ccc(-c2nnco2)cc1)C(=O)NC1CCCCC1C +CC(O)CC(C)(C)CNC(=O)Nc1cc(F)cc(N2CCCC2)c1 +NC(=O)C1CCCN(C(=O)Cc2c(Cl)cccc2Cl)C1 +CCn1cc(C(=O)N2CCN(Cc3ccccc3)C(C#N)C2)cn1 +CC(=O)N1CCc2[nH]nc(-c3ccc(-c4ccccc4)cc3)c2C1 +O=C(CSc1nc(-c2ccccc2)c[nH]1)NCC1CCCO1 +Cc1cc2c(c(C(O)C3CCCCC3)c1)NC(=O)C2 +Cc1ccc(C)c(NC(=O)CC2C(=O)Nc3nc(C)nn32)c1 +Cc1ccc(CC(=O)NCc2ccnc(OC3CCC3)c2)cc1 +COc1cc(N(C)Cc2cc(-c3ccccc3)no2)nc(N)n1 +COc1cccc(OC)c1C(=O)N(C)c1cccc(SC)c1 +Cc1cc(C)n2nc(C(=O)N3CCN(C)c4ccccc4C3)nc2n1 +CCCNC(=O)CNC(=O)NCc1cccc(OC)c1 +Cn1c(C(=O)Nc2nncs2)c(Cl)c2ccccc21 +Cc1noc(CCC(=O)NC(CC(C)(C)C)c2ccc(F)cc2)n1 +CCn1nnc2cc(C(=O)NCC3(C(N)=O)CCOCC3)ccc21 +Cc1cccc(C(=O)N2CCC(O)C2Cc2ccccc2)n1 +CCn1cc(N)cc1C(=O)N1CCCC(C(N)=O)C1 +Cn1cnc(-c2ccc(NC(=O)C3CC=CC3)cc2)n1 +C=CCN(CC(F)(F)F)C(=O)c1c(F)ccc(OCC)c1F +CSc1nnc(NC(=O)c2cc(-c3cccc(C)c3O)n[nH]2)s1 +CC(C)n1c(SCCCCC(N)=O)nc2ccccc2c1=O +Cc1ccccc1NC(C(N)=O)c1ccc(Br)cc1 +Cc1cc(NC(=O)c2ccccc2C(=O)Nc2cc(C)[nH]n2)n[nH]1 +CC1=C(C(=O)Nc2ccccc2C)C(c2ccccc2)n2ncnc2N1 +COCCNC(=O)C1(c2cc(-c3ccccc3)on2)CC1 +Cc1ccc(NC(=O)c2cc(C)n[nH]2)c(OCC(=O)N(C)C)c1 +CCCc1noc(C2CCCN(C(=O)COc3ccccc3)C2)n1 +CNS(=O)(=O)c1ccc(CCC(=O)NC2CCCCCC2)cc1 +O=C(OCC1CCC1)c1nc(C2CC2)n(-c2ccccc2)n1 +COc1ccccc1OCCN(C)C(=O)c1cn(C)nc1C(C)(C)C +CCC1CCC(N(C(=O)C2CC(=O)N(C3CC3)C2)C2CC2)CC1 +N#CC(C(=O)CCCc1ncc(-c2ccccc2)o1)c1ccccn1 +CC(=O)N1CCc2nc(C(=O)Nc3ccc(Cl)cc3)sc2CC1 +CNc1nc(-c2ccc(C)n(C3CCCC3)c2=O)cs1 +CN(Cc1ccc(O)cc1)C(=O)c1ccc(N2CCCCC2=O)cc1 +COc1cc(C(C)=O)ccc1OCC(=O)NCC1CC1 +CCCNc1nnc(-c2cccn(CC)c2=O)s1 +O=C(NC12CC3CC(CC(C3)C1)C2)C1CCN(c2cnccn2)CC1 +Cc1ccc(NC(=O)COc2ccc(F)cc2)cc1F +CCN(CC)C(=O)COC(=O)c1cc2c(s1)-c1ccccc1OC2 +O=C(NCCC1=CCCCC1)c1cc(-c2ccc(O)cc2)n[nH]1 +O=C(c1cnc2ccc(F)cc2c1O)N1CCCc2ccccc21 +CCN(CC)C(=O)C1CCC(=O)N(C)C1c1ccccc1F +CCN(CCC(=O)OC)Cc1cnc2ccc(C)cn12 +CC(=O)Nc1ccc(SCC(=O)Nc2cc(C)no2)cc1 +Cc1ccc(CCNC(=O)NCCC(=O)N(C)C)c(C)c1 +Cn1c(=O)[nH]cc(C(=O)Nc2ccccc2-c2ccccc2)c1=O +Cc1nsc(N2CCN(CCn3c(=O)oc4cccnc43)CC2)n1 +CN(CC(=O)Nc1nc(-c2ccco2)cs1)C(=O)OC(C)(C)C +Cc1cccc(CN2CCN(Cc3ccc(C)c(C)c3)C(=O)C2)n1 +Cc1ccc(SCCN(C)C(=O)c2ccnc(C(C)C)n2)cc1 +Cc1nccn1-c1ncccc1NC(=O)Cc1cccc(OCC#N)c1 +Nn1c(SCc2cccc3c2OCCO3)nnc1-c1ccco1 +COc1ccc(NC(=O)c2c(C)nn(C)c2C)c2cccnc12 +O=C(OCc1cccs1)C1CCN(C(=O)c2ccccn2)CC1 +CCOC(=O)C1(NC(=O)c2ccc(C)n2C)CCCC1 +COC(=O)C1(NC(=O)CCc2ccco2)CCCC1 +CCOc1ccc2cc(C(=O)NCc3ccccc3)c(=O)oc2c1 +Cc1cc(C(C)NC(=O)N(C)CC2CC2)c(C)s1 +CCNC(=O)COc1nc(-c2ccccc2Cl)no1 +COCCN1CC2=C(C1=O)C(c1ccc(OC)c(OC)c1)NC(=O)N2 +Cc1ccc(-c2ncco2)cc1NC(=O)Cn1ccccc1=O +COc1cccc(C(=O)Nc2ccc(C)c(C(=O)NC(C)C)c2)c1F +COc1ccc2nc(COC3CN(CCC(C)C)CC3F)[nH]c2c1 +Cc1cc(C)cc(-c2cncc(C(=O)NCc3ccco3)c2)c1 +O=C(c1ccc(-c2ccccn2)s1)N1CCCCC1 +COc1ccc(NC(C)=O)cc1-c1ncc(N)cn1 +NS(=O)(=O)c1cccc(NC(=O)CCCOc2ccccc2)c1 +Cc1ccc(F)cc1S(=O)(=O)N1CCC(CO)CC1 +Cc1nsc(NC(=O)c2ccc(Cl)cc2Cl)n1 +Cc1oc(-c2ccccc2)nc1CC(=O)NC1CC1 +CCC(COC)NC(=O)C(C)Sc1ccccn1 +CN(CCNC(=O)C1CCCN(C(N)=O)C1)c1ccccc1 +CC(c1ccccc1)N1C(=O)CCC1n1nnc2ccccc21 +CC(C)CNC(=O)C1CCCN(C(=O)NCC(C)C)C1 +O=C(Nc1ccc(S(=O)(=O)N2CCCCC2)cc1)N1CCCC1 +N#Cc1ccc(C(=O)N2CCC(OCCCc3ccccc3)C2)nc1 +Cc1ccc(CCC(=O)OCC(=O)NC2CC2)cc1Cl +COC(=O)c1cc(NCc2cnc(C)s2)ccc1F +CCOC(=O)c1noc2nc(C)nc(NC3CCCC3)c12 +COc1cc(C(=O)N2CCN(Cc3ccccc3)CC2C)ccc1C +CC(C)N(CC(N)=O)c1ncnc2sc3c(c12)CCC3 +COC1CCCC(OC(=O)Cn2nc(C)c(Cl)c2C)C1 +CC(C)(C)c1cc(CNC(=O)c2ccc3cccc(F)c3n2)n[nH]1 +O=C(NCCc1ccc(OCc2ccccc2)cc1)C1CCCO1 +CC(C)NC(=O)C1CCCN1C(=O)OCc1ccccc1 +COc1ccc(Cl)cc1NC(=O)NCC1CCCCO1 +Cc1cn[nH]c1C1CCCN(Cc2ccc3c(c2)OCO3)C1 +CC(=O)NC(CC(=O)NCCc1ccc(F)cc1C)c1ccccc1 +O=C(CCCC(O)c1ccc(Cl)cc1)NC1CC1 +CCOC(=O)C(C)Sc1ccc2nnc(-c3ccccn3)n2n1 +CCCC(=O)NC(C(=O)N1CCNCC1)C(C)C +CCCn1nc(C(=O)Oc2ccccc2OC)ccc1=O +COc1ccc(NC(=O)c2ccccc2Cl)cc1OC +O=S(=O)(Nc1cnn(C2CCOCC2)c1)c1ccccc1 +CC(C(=O)Nc1ccc(F)cc1)N1C(=O)CNc2ccccc21 +CCN(CC)C(=O)CCCNC(=O)c1cc2c(F)cccc2[nH]1 +CCc1c(C)cc(C(=O)N2CCC(CO)C(O)C2)c(=O)n1C +O=C(NCCn1nc(-c2ccc(F)cc2)oc1=O)OCC(F)(F)F +COc1ccc(N)cc1NC(=O)C(C)OCc1ccco1 +CNC(=O)c1ccccc1C#CCNS(=O)(=O)C1CC1 +CC(=O)c1ccc2c(c1)N(CC(=O)NCC(C)C)C(=O)C(C(C)C)O2 +CN1CC(C(=O)N2CCN(c3ncnc4sccc34)CC2)CC1=O +NC(=O)c1cnc(NC(=O)COc2ccc(Cl)cc2Cl)s1 +CSc1ccc(C(O)CNC(=O)Nc2ccc3c(c2)OCO3)cc1 +Cc1noc(C)c1C1CCCN1C(=O)c1cnc(C2CC2)[nH]c1=O +Cc1cccc(OC(=O)Cn2nc(C)c(Cl)c2C)c1C +Cc1ccc(NC(=O)N2CCN(C(=O)CCc3ccco3)CC2)cc1 +CC(C)Nc1nc(-c2ccc(F)cc2)ccc1C#N +Cc1cccc2c(Sc3ccccc3S(C)(=O)=O)ncnc12 +CC(=O)NCCCNC(=O)Nc1ccc2c(c1)COC2 +CC(C)COC(C)c1noc(Cn2nccc2-c2ccncc2)n1 +O=C(COC1CCCCC1)NCC1(c2cccc(F)c2)CCOCC1 +COc1ccc(-c2ccc(C(N)=O)o2)c(Br)c1 +CCC1CCCCC1NC(=O)Nc1ccc(C(=O)N2CCCC2)cc1 +COCCOC(C)C(=O)Nc1ccc(F)c(N)c1 +CCOc1ccccc1CCC(=O)N1CCc2ncncc2C1 +Cc1cc(CNC(=O)c2coc(COc3cccc(F)c3F)n2)n[nH]1 +CCN(Cc1cccc(C)c1)C(=O)c1ccc(C(=O)N(C)C)cc1 +N#Cc1cccc(C(=O)NCCN2CCOCC2)c1 +Cc1cccc(OCCN2CCN(C(=O)C3CC3)CC2)c1 +COc1cccc(NC(=O)c2ccn(-c3ccc4ccccn34)n2)c1 +CC(Oc1ccccc1-c1cc2ccccc2o1)C(N)=O +COCCN1CC(C(=O)N2CCC(OCC(C)C)CC2)CC1=O +CC1CC(=O)c2c(OCC(=O)c3ccc4c(c3)OCO4)ccc(F)c21 +CCc1cccc(C)c1NC(=O)C1CC(=O)Nc2cc(F)ccc21 +CC(=O)c1cc(CC(=O)NCc2ccc(Cl)cc2)cs1 +COc1ccc(Cl)cc1N1C(=O)CCS1(=O)=O +Cc1nc(C(=O)NC(C)c2cccc(F)c2)cs1 +C=CCOCC1CCC2C1OCCN2C(=O)c1ccc(Cl)cc1 +Cc1ncc2c(c1C#N)CCN(CCC(=O)N1CCCC(C)C1)C2 +Cc1cc(C)c(NC(=O)CSc2ncccn2)c(Cl)c1 +O=C(N1CCN(c2ccccn2)CC1)C12CC3CC(CC(C3)C1)C2 +COc1ccc(-c2cc(CC#N)c(C)o2)c(OC)c1 +CCC(C)n1nccc1NC(=O)c1cccc(Br)c1 +COC(=O)Cc1ccc(OCC(=O)N(C)C2CCCCC2)cc1 +CCc1cc(N)cc2c(=O)cc(C(=O)NCCC(C)C)oc12 +CNC(=O)c1ccc(NC(=O)c2ccc(F)nc2)cc1Cl +CSc1nsc(SCCC(=O)Nc2nccs2)n1 +Cc1ccc(NC(=O)CCn2cnc3sccc3c2=O)cc1Cl +Cc1nnc2n1CC(NC(=O)COCCOc1ccccc1)CC2 +Cc1cccc(-c2n[nH]cc2-c2nc(C3CC3)n[nH]2)c1 +Cn1cc(CC2CCN(C(=O)c3ccc(-n4ccnn4)cc3)C2)cn1 +O=C(OCC1CCOCC1)c1cccc(OCC(F)F)n1 +O=C(CCc1n[nH]c2c1CCCC2)NCC(F)(F)F +O=C(NCc1ccccc1Cn1cncn1)c1ccc(F)cc1Cl +CC(C)CN(Cc1ccccn1)C(=O)C1CCCN(C(=O)N(C)C)C1 +CCC(CNC(=O)Cn1ccnc1)Oc1cccc(F)c1 +CCOc1cc(CN2CCOCC2C)cc(Cl)c1OC +CC(C(O)c1ccccc1)N(C)Cc1ccccc1 +CC1CCCCC1n1c(=O)[nH]c2ccccc2c1=O +O=C1CCC2C(CCN2C(=O)c2cnccn2)N1Cc1ccncc1 +Cc1cccc(N)c1NS(=O)(=O)c1cn[nH]c1 +COC(=O)c1sccc1NC(=O)CN1CC(C)c2ccccc21 +CCC(=O)N1CCN(CC=Cc2ccccc2)CC1 +CCc1[nH]c2ccccc2c1C(=O)c1cccnc1 +Cc1ccc(CN(C)C(=O)Cn2c(=O)cnc3ccccc32)cc1 +CN(Cc1cnn(C)c1)C(=O)CCCNC(=O)C1CC1 +Cc1n[nH]c(C)c1C1CCCCCN1C(=O)NC(C)c1nncn1C +N#Cc1ccc(Cn2c(C#N)nc3ccc(F)cc32)cc1 +COC(=O)N1CCc2ccc(NC(=O)NCc3cccs3)cc2C1 +COCC(C)(O)CNS(=O)(=O)c1ccc(OC)c(Cl)c1 +CN(Cc1ccccc1)C(=O)C1CN(S(C)(=O)=O)C1 +CCCn1c(C)nnc1SC(C)C(=O)Nc1cccc(C(C)=O)c1 +CC(C)(C)NC(=O)Cn1c(SC(F)F)nc2ccccc21 +O=C(Cc1ccc2c(c1)OCCO2)OCc1nc2ccccc2s1 +Cc1ccc(NC(=O)CSc2ccccc2C(=O)NC2CC2)cc1 +COc1cc(N2CCC(c3nc4ccc(F)cc4[nH]3)CC2)nc(N)n1 +CC1CCCN(C(=O)c2ccc(S(=O)(=O)N(C)C)cc2)C1 +Cn1cc(Cl)cc1C(=O)NCC1CC=CCC1 +CC(C)OC(=O)c1cccc(NC(=O)c2ccco2)c1 +O=C(COC(=O)c1cnc2ccccc2n1)C1=NC=CC1 +COc1cc(CNc2cccc(O)c2)ccc1Cl +COc1cc(F)ccc1NCc1nsc(N(C)C)n1 +COc1ccc(Cc2nc(N)nc(C)c2C(=O)N(C)C)cc1 +CCn1cnnc1CNC(=O)Nc1cc(Br)ccc1C +Cc1cc2c(c(-c3ccccn3)c1)OC(CNC(=O)c1ccco1)C2 +CCNC(=O)C1CCN(Cc2nc3cc(Cl)ccc3n2C)CC1 +CN(C(=O)c1ccn(-c2ccc(F)cc2)n1)c1ccccc1F +Nc1cc(N2CCCC2)nn1-c1ccc(Cl)cc1 +COc1cc(C(=O)Nc2cccc(N)c2)ccc1C +CCOCC(C)NC(=O)c1ccc(C#CCO)cn1 +Cc1cccc(NC(=O)CN(C)C(=O)C2CC=CC2)n1 +O=C(NC1CCC2(CC1)OCCO2)N(CCCCO)C1CC1 +COCC(C)NC(=O)CNC(=O)c1ccc2ccccc2c1 +COc1cccc(C(=O)OCC(=O)Nc2cc(C)ccc2OC)c1 +Cc1cc(C)n(-c2ncnc(N3CCCCC3)c2N)n1 +C#CCN1CCN(C(=O)NCC(=O)N2CCc3sccc3C2)CC1 +O=C(Cc1nc2ccc(Cl)cc2c(=O)[nH]1)Nc1ccc(F)cc1 +CC(=O)Nc1ccc(NC(=O)c2csc(C)n2)cc1 +CC(C)c1cc(C(=O)N2CCCC(C(=O)c3cccs3)C2)on1 +NC(=O)C1CCCN(C(=O)Nc2ccc(-n3cncn3)cc2)C1 +CC(=O)Nc1sc2c(c1C(=O)Nc1ccccc1Cl)CCC2 +O=C(c1ccc[nH]c1=O)N1CCCC1c1ccsc1 +CN(C)C(=O)COC(=O)c1nn(-c2ccc(F)cc2)c2c1CCC2 +Cn1cc(CNC(=O)C2(c3ccc(F)cc3F)CCOCC2)cn1 +CSc1ncccc1C(=O)N(C)Cc1cc(C)on1 +CCOC1CCCN(C(=O)Nc2cccnc2OCCOC)C1 +Cc1nc(C)n(CCNC(=O)Nc2cc3c(cc2C)OCO3)n1 +Cc1nc2ccccc2n1CCNS(=O)(=O)c1ccccc1Cl +Cc1ccncc1NC(=O)NCCCC(=O)N1CCc2ccccc21 +CCc1nnsc1C(=O)N1CCc2cc(OC)c(OC)cc2CC1 +O=C(c1cnn2c(C(F)F)cc(C3CC3)nc12)n1cccn1 +CNc1nnc(-c2ccc(OC)cc2OC)s1 +Cc1ccn2c(=NC(=O)c3csc(-c4ccco4)n3)[nH]nc2c1 +CCSc1nnc2c(S(=O)(=O)N3CCOCC3)cccn12 +COc1cccc(OC)c1C(=O)NCCc1ccoc1 +O=C(OCCOc1cccc(Cl)c1)c1cnc2ccccn2c1=O +CCC(C)n1ncc(C(=O)NCc2cccc(N(C)C)c2)c1C1CC1 +N#Cc1ccc(-c2cccnc2)n(CC(=O)NCc2ccccc2)c1=O +CC(C)(C)CCNC(=O)Nc1cccc(C(N)=O)c1 +CCCn1c(NS(=O)(=O)c2c(C)noc2C)nc2ccccc21 +O=C(NCCN1CCN(C(=O)c2cnccn2)CC1)c1cccs1 +O=c1c2ccccc2nnn1CSc1nncn1Cc1ccco1 +CCCn1nc(C(=O)NC(C)c2ccc(F)c(F)c2)ccc1=O +CCN(CCc1ccccn1)Cc1nnc(-c2ccc(Cl)cc2)o1 +CCC(C)C(=O)N1CCN(c2ccccc2F)CC1 +Cc1n[nH]c(C)c1N1CCN(C(=O)C2CC=CCC2)CC1 +NS(=O)(=O)c1ccc(Cl)c(C(=O)NCc2cccnc2)c1 +Cn1cc(NC(=O)c2sc3cc(F)ccc3c2Cl)cn1 +NS(=O)(=O)CC1CCCN1C(=O)CC1CCCCC1 +COc1ccc(C(O)C(=O)NCC2CCCO2)cc1 +CSc1ccc(Cl)c(C(=O)Nc2cn(C)c(=O)cc2C)c1 +COc1cccc(CNC(=O)c2ccc(O)cc2)c1 +Cc1nc(C)c(C(=O)OCC(=O)N(C)c2ccccc2)s1 +O=C(Nc1nc(C(=O)N2CCc3ccccc3C2)co1)c1ccccc1 +CCC(=O)Nc1cccc(-c2nn3c(C)nnc3s2)c1 +CC(C)c1cc(NC(=O)C2CCCN2C(=O)Cc2cccs2)[nH]n1 +CC(C)NC(=O)COC(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +CN(C)C(=O)Cc1nc(CSc2nc(N)cc(N)n2)cs1 +CCOC(=O)c1cn(CC(C)C)c2nc(C)ccc2c1=O +COc1ccc(CNC(=O)COCC2CC2)cn1 +COC(=O)c1ccc2c(=O)[nH]c(Cc3ccn(C(C)C)n3)nc2c1 +CCOc1cccc(CNc2ccc(N3CCCC3=O)cc2)c1 +CCn1nnc2cc(C(=O)OCC(=O)Nc3cccc(C)c3)ccc21 +Brc1ccccc1-c1nc2ncccc2[nH]1 +CC(Sc1cccc(F)c1)c1nc(C2CC2)no1 +CCc1ccc(OC)c(S(=O)(=O)NC(C)CC)c1 +O=C(CS(=O)(=O)c1ccc(Cl)cc1)NCc1ccc(F)cc1 +C#CCn1c(=O)n(-c2ccc(F)cc2F)c(=O)c2sccc21 +Cc1csc(N2CCN(CCS(=O)c3ccccc3)CC2)n1 +CC(C)C(NC(=O)c1cccs1)C(=O)NCCc1cccc(F)c1 +CN(C)C(=O)CNc1cccc(OCC(=O)N(C)C)c1 +CN1C(=O)CCc2cc(NC(=O)Nc3ccc4c(c3)OCO4)ccc21 +Cc1[nH]c2ccccc2c1C(=O)Nc1ccc(CNC(N)=O)cc1 +CS(=O)(=O)c1ccc(C(=O)Cc2cscn2)o1 +CC(=O)N1CCc2cc(NC(=O)C(C)Oc3cccc(C)c3)ccc21 +CNC(=O)C1CCCN1S(=O)(=O)N1CCCCCC1 +CSc1nnc(Sc2nccnc2C#N)s1 +CCC1CN(C(=O)C2CC(=O)N(Cc3ccccn3)C2)CCO1 +CCOc1cc(S(=O)(=O)N2CCN(C(C)=O)CC2)ccc1Cl +O=C(CN1CCCc2cccc(F)c21)NC1CCOCC1 +COc1ccsc1C(=O)NC1CCN(c2c(F)cccc2F)C1 +c1ccc(OCc2noc(-c3ccc(Cn4ccnc4)cc3)n2)cc1 +Cc1ccc(-c2csc3nnc(CO)n23)s1 +CC(CNC(=O)c1ccn(C)c(=O)c1)Oc1ccccc1 +Cc1cc(C)nc(C2CCN(C(=O)Cc3c(C)noc3C)C2)n1 +CCCCc1c(C)nc2nc(SCC(=O)NC3CC3)nn2c1C +COCC(=O)Nc1ccc(CC(=O)N2CCCC2)cc1 +O=C(COC1CCCC1)Nc1nc(C2CC2)cs1 +CC1Sc2ccc(C(=O)Nc3nccs3)cc2NC1=O +Cc1cc(-c2ccc(CNn3nnnc3N)o2)ccc1Br +COCCn1cc(C(=O)N2CCC(c3nc(C)no3)CC2)ccc1=O +CCOC(C)C(=O)Nc1ccccc1C(=O)OC +COCC(C)NC(=O)Cc1coc2cc(C)c(C(C)C)cc12 +CC(Oc1ccc(F)cc1Cl)C(=O)N1CCN(C)CC1 +Oc1c(Cl)cc(Cl)c2c1CCNC2c1nc[nH]n1 +COc1cc(CNC(=O)CCc2ccsc2)ccc1C +Cc1n[nH]c(C)c1NC(=O)c1ccc2[nH]nnc2c1 +NS(=O)(=O)c1ccc(Nc2nc(-c3cccnc3)cs2)cc1 +Cn1nnc(CO)c1-c1ccc(Br)cc1 +CN(C)c1cc(C(=O)N2CCc3c(Cl)cccc32)ccn1 +CCc1nc(C(=O)NCc2nc(C)sc2C)c[nH]1 +Cc1n[nH]c(C)c1NC(=O)c1cnn(-c2ccncc2)c1C +COc1ccc(C)c(NC(=O)NCCN2CCNC2=O)c1 +O=C(NCc1ccncc1)Nc1nnc(C(F)(F)F)s1 +CCn1cc2c(n1)C(COC)CN(Cc1ccccn1)C2 +O=C(CCC(=O)c1ccc(F)c(F)c1)NCc1ccccc1Cl +Nc1ncnc(Nc2nc3ccccc3s2)c1N +CCC(NC(=O)Nc1cc(C(N)=O)ccc1C)c1ccc(OC)cc1 +NC(=O)c1csc(C(=O)NCC2(c3ccccc3)CCC2)c1 +O=C(Nc1ccc(OC(F)(F)F)cc1)C1COc2ccccc2O1 +CC1CC1c1ccc(C2Nc3ccccc3C(=O)N2C2CC2)o1 +Cc1cc(NC(=O)N(C)C(C)c2ccc(F)cc2)no1 +CC(=O)NC(C)(C)c1noc(CCn2c(=O)oc3ccccc32)n1 +CSc1n[nH]c2ncnc(N3CCC(C(N)=O)CC3)c12 +N#Cc1c2c(cn(-c3ccccc3F)c1=O)CCCC2 +Cc1ccc(C(=O)N2CCC(C(=O)Nc3ccncc3)CC2)cc1F +N#Cc1ccc(-c2noc(-c3cc(-c4ccc(F)cc4)[nH]n3)n2)nc1 +O=C(CNC(=O)c1ccc(C(F)(F)F)cc1)Nc1cccc(F)c1 +Cc1ccc(CN(C(=O)c2cc(Br)c[nH]2)C(C)C)o1 +Cc1ccc(CNc2ccn(CCC(N)=O)n2)c(Br)c1 +COc1ccc(F)cc1C(C)NC(=O)CCn1c(C)csc1=O +O=C(c1ccc2cccc(F)c2n1)N1CCN(c2cnccn2)CC1 +N#Cc1ccccc1S(=O)(=O)N(CCO)CCc1ccccc1 +O=C(Nc1nccs1)N1CCC(c2nnc3n2CCC3)CC1 +Cc1noc(C)c1CC(=O)Nc1ccc(Br)cc1O +Nc1nc(Nc2ccccc2)nc(C2CCCCC2=O)n1 +Cc1ccc(NCc2nnc(C(C)(C)C)o2)c(OCC(=O)N(C)C)c1 +COc1cc2c(c(Cl)c1OC)CCNC2C1CC(=O)C1 +CC(C)(C)OC(=O)NCCC(=O)NCc1ccc(Cl)cc1 +Cn1nnnc1SCCNC(=O)C(c1cccnc1)N1CCCC1 +CCNC(=O)c1nn(CC)c2ccc(F)cc2c1=O +Cc1ccc(-c2nc(CNC(=O)c3cc(C(N)=O)cs3)co2)cc1 +Cn1ncc(C(=O)Nc2nccs2)c1C(=O)Nc1nccs1 +Cc1cccc(NC(=O)CCC2NC(=O)c3ccccc3NC2=O)n1 +CCC(=O)Nc1ccc(N2CCCC2=O)c(Cl)c1 +Cc1ccccc1Cn1cc(NC(=O)c2ccc(F)cc2)cn1 +CCc1cccc2c(CN3CCc4c(nc(C)[nH]c4=O)C3)c[nH]c12 +N#Cc1ccccc1NC(=O)c1ccc(N2CCCS2(=O)=O)cc1 +Cc1nn(C)cc1CN(C)S(=O)(=O)c1c(C)nn(C)c1C +CC(C)NC(=O)Cc1ccc(NCc2ccc3c(c2)OCCO3)cc1 +CS(=O)(=O)c1ccc(F)c(NCC(=O)NC2(C#N)CCCC2)c1 +Cn1cc(N2CC3(CCN(C(=O)c4ccncc4)C3)CC2=O)cn1 +NC(=O)c1ccc(N2CC(C(N)=O)CC2=O)c(Cl)c1 +CC(COc1ccc(F)cc1)NC(=O)C1CC(=O)Nc2ccccc21 +CNC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(NC(C)=O)cc1 +Cc1nc(C)c(C(=O)N(C)c2ccc(Br)cc2C)s1 +COc1ccc(CNC(=O)Cc2cc(-c3ccccc3F)on2)cc1 +COc1ccc2[nH]cc(C3CCN(C(=O)NC4CC4)CC3)c2c1 +CCC1CN(C)c2ccccc2CN1C(=O)CCCCOC +Cc1ccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)o1 +Cc1cc(C(=O)N(CC(C)C)C2CC2)c2cnn(C(C)C)c2n1 +CC(=O)c1ccc(OC(=O)Cc2cccc(OCC#N)c2)cc1 +O=C(NCc1ccccc1CO)c1c[nH]nc1-c1ccccc1F +O=C(CCn1cncn1)NCc1nc2ccccc2[nH]1 +CCNC(=O)CCC(O)c1cccc(Br)c1 +CCc1noc(CC)c1CNC(=O)N(Cc1ccc(C)o1)C(C)C +Cc1ccc(OCC(O)Cn2c(C3CC3)nc3ccccc32)cc1 +COc1ccccc1CC(=O)Nc1ccc(F)c(NC(C)=O)c1 +CNc1snc(C)c1C(=O)OCc1cc(C)on1 +CN(C1CCCCC1)S(=O)(=O)N1CCn2c(nn(C)c2=O)C1 +COc1ccc(F)c(CNc2cc(N)nc(C)n2)c1F +CCOCCCNC(=O)c1ccc(C)c(-n2nnc3cccnc32)c1 +CN(C)C(=O)Cc1ccc(NC(=O)Nc2cccs2)cc1 +CCN1CCN(S(=O)(=O)c2cc(C)c(C)cc2C)CC1 +Cc1noc(C)c1C(=O)NCC1Cc2cc(-c3cccnc3)ccc2O1 +Cc1cc(C(O)C2CCCO2)c2c(c1)C(C)(C)C(=O)N2 +CC(NC(=O)COc1cccc2cccnc12)c1ccco1 +Cc1ccc(NC(=O)c2cnn3c2CCCC3)c(C)c1 +Cc1ccc(NC(=O)c2ccco2)c(NC(=O)C2CCCO2)c1 +CCc1nc(C)c(C(=O)N2CCC(O)(c3cccnc3)CC2)s1 +Cc1ccc(CN(C)C(=O)c2ccc(-c3cscn3)cc2)o1 +O=C(NCCOc1ccccc1)c1cccnc1N1CCOCC1 +COC(=O)c1cc(S(=O)(=O)Nc2ccc(OC)cc2)cn1C +CCn1cc(C(C)NC(=O)Nc2ccc3c(c2)OCO3)c(C)n1 +CC(C)OCc1cccc(CNC(=O)c2cnn3c2SCC3)c1 +OCCNc1nc2ccccc2n1Cc1ccc(Br)cc1 +Cc1n[nH]c(C)c1NC(=O)CNC(=O)c1cc(F)cc(F)c1 +Cc1ccc(C(=O)Nc2cc(NC(=O)c3ccccc3)ccc2C)cn1 +O=C(NCc1cccnc1)c1cn2c3c(cccc3c1=O)CCC2 +CCC(NC(=O)CN(C)S(C)(=O)=O)c1ccccc1OC +CC1CNc2cc(S(=O)(=O)NC3CCCCCC3)ccc2O1 +CC(C(=O)Nc1ccc(C#N)cn1)c1ccsc1 +O=C(c1cncn1-c1ccc(F)cc1)N1CCCCCC1 +COC(=O)CCNC(=O)CSc1ccccc1F +CCCCCNC(=O)c1c(C)c(C)nn(C)c1=O +O=c1ccn(-c2ccc(F)cc2)nc1-c1cc[nH]n1 +O=C(NC1CC1)c1cccc(-c2c[nH]c(=O)[nH]c2=O)c1 +Cc1cc(O)c2c(=O)c(-c3csc(C)n3)coc2c1 +CN(CCN(C)C(=O)OC(C)(C)C)Cc1nccc(N)n1 +COC(=O)NCCC(=O)NC(C)Cc1cccc(Br)c1 +CCCc1cc(NC(=O)C(Cc2ccccc2)n2nnnc2C)n[nH]1 +CCc1nc2n(n1)CCCC2NC(C(N)=O)c1ccccc1 +CCn1cc(CN(CCOC)C(=O)c2c(C)cc(C)[nH]c2=O)cn1 +CNC(=O)COC(=O)c1cccc(NC(=O)C(C)(C)C)c1 +Cc1nc(C)c2c(C)c(C(=O)Nc3cc[nH]n3)sc2n1 +NC(=O)CN(Cc1ccccc1)C(=O)CC1CCCCC1 +COC(=O)Cc1ccc(OCC(=O)Nc2c(C)cc(C)cc2C)cc1 +N#Cc1ccc(CNC(=O)CCC(=O)c2ccc(F)cc2F)c(F)c1 +NC(=O)C1(N2CCN(C(=O)c3ccc(F)cc3)CC2)CCCCC1 +CC1CC1CNC(=O)Cn1ccc2ccc(Cl)cc21 +O=C(COC(=O)COc1ccccc1)NC1CCCc2ccccc21 +CC(C)c1nc2ccc(NC(=O)CC(F)(F)F)cc2s1 +CC(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2)C1C(C)C +Cc1cccn2c(=O)c3c(nc12)CCN(C(=O)C(C)(C)C)C3 +COc1ccc(S(=O)(=O)N2CCOCC2)cn1 +CC(=O)NC1CCC2(CC1)CNC(=O)c1ccccc1O2 +CC(C)Oc1ccc(CNC(=O)CC(F)(F)F)cc1F +COc1cccc(NC(=O)C2CC(=O)N(Cc3ccccc3F)C2)c1 +Cc1cccc(CNC(=O)CSc2ncn[nH]2)c1 +COc1cccc(C(=O)N(C)C)c1OCC(=O)Nc1ccccc1 +O=C(Nc1ccc2c(c1)COC2)c1ccn(-c2ccccc2F)n1 +CCn1c(C(=O)Nc2n[nH]c(-c3ccco3)n2)cc2ccccc21 +CNC(=O)c1ccccc1NC(=O)c1ccc(OC(C)C)cc1 +CC(NC(=O)NCC1CC12CCCc1ccccc12)c1cnn(C)c1 +O=C(c1cccc(-n2cccn2)n1)N(Cc1ccncc1)C1CC1 +CCOc1ccccc1OC(=O)c1cnn(C(C)(C)C)c1 +CC(C)C(=O)N(c1nnc(-c2ccncc2)s1)C(C)C +C=C(C)CN(CC)C(=O)NCc1cccc(S(N)(=O)=O)c1 +COc1cc(CNC(=O)CSc2nccn2C)ccn1 +Cc1ccc(NC(=O)c2cccc(NS(C)(=O)=O)c2)c(C)c1 +COc1ccc(C(C)N(C)C(=O)c2cc(C(N)=O)cs2)cc1 +COc1cc2ccccc2cc1C(=O)OCC(N)=O +COCc1ccc(C(=O)Nc2ccc(-n3cnc4ccccc43)nc2)o1 +CCS(=O)(=O)N(C)CC(=O)Nc1ccccc1SC +O=C(CCNC(=O)c1cccs1)NCCC(=O)N1CCCC1 +Cc1cc(N2CCCC2c2cc(=O)cc(C)[nH]2)ncn1 +Cc1nn(C)c(C)c1C(C)C(=O)Nc1nc(-c2ccco2)cs1 +COc1cccc(CC(=O)N2CCC(C(=O)c3nccs3)CC2)c1 +Cn1nnc2cc(C(=O)NC3(C)Cc4ccccc4C3)ccc21 +CC(C(=O)c1c(N)n(C)c(=O)n(C)c1=O)N1CCc2ccccc21 +CCCCc1noc(C(C)n2nnc(-c3cccc(F)c3)n2)n1 +O=C(NCCC1CC1)c1ccnc(OC2CCOC2)c1 +OC1=Nc2c(ncn2-c2cccc(Cl)c2)C(c2cccc(O)c2)C1 +COc1ccccc1NC(=O)Cn1[nH]c(=O)c2ccccc2c1=O +CC(=O)NCC(=O)NC(C)c1cccc(Br)c1 +COc1ccc(NC(=O)CCC(=O)NCc2ccco2)cc1 +Cc1cc(C(=O)NCCNc2ncccc2C#N)[nH]n1 +COC(=O)Nc1cccc(OCc2nc(-c3ccsc3)no2)c1 +CCOc1cc(F)ccc1NC(=O)c1csnn1 +COCc1nc(C(=O)OCc2nnc(-c3ccccc3)n2C)cs1 +Cc1ccc(Cl)cc1S(=O)(=O)N1CCC(CO)CC1 +O=C(NCCn1nnn(-c2cccs2)c1=O)c1cccs1 +Cn1c(C(=O)NCc2ccco2)c(Br)c(=O)n(C)c1=O +COCCN1CCN(S(=O)(=O)c2cc(F)ccc2C)CC1=O +O=C(NCc1cccnc1)c1nc2c(o1)CN(Cc1cccnc1)C2 +O=C(Nc1ccc(F)c(C(F)(F)F)c1)c1csnn1 +COc1ccc(OC)c(-c2ccc(N)c(=O)n2C2CC2)c1 +CCOc1ccc(OCC(=O)N(CC)C2CC2)cc1 +[H]N=c1n(N)c2ccccc2n1CC(=O)c1ccccc1 +CCCn1ccc2c(cnc3c(C(=O)OC)c(C)nn32)c1=O +Cc1nc(N)c2c(ncn2C2OC(CO)C(O)C2O)n1 +CCC(C)NS(=O)(=O)c1cc(-c2ccc(=O)[nH]n2)ccc1C +CNS(=O)(=O)c1ccc(C(=O)N(C)CC(F)(F)F)cc1 +COc1ccc(Nc2ncnc3[nH]ncc23)cc1OC(F)F +Cc1cc(C)cc(C(=O)NCC(=O)N(C)CCNC(=O)C(C)C)c1 +Nc1cc(C(=O)N2CCOCC2)ccc1CN1CCOCC1 +CCOc1ccccc1NC(=O)c1nnn(-c2ccccc2C)c1N +Cc1ccc(C(=O)Oc2ccc(OCc3ccncc3)cc2)c(=O)[nH]1 +CCCCNC(=O)COc1nc(-c2cnccn2)nc(C)c1C +CCC(=O)OCC(=O)c1c(F)c(F)c(F)c(F)c1F +CNC(=O)c1cccc(NC(=O)N(CC(C)C)CC(C)C)c1C +COc1cccc(CCC(=O)Nc2cc(-c3ccsc3)no2)c1 +CCc1nn(Cc2ccccn2)c(=O)c2cc3sc(C)cc3n12 +CC(C)c1nnc(NC(=O)c2c[nH]nc2-c2ccccc2Cl)s1 +CC(CN1CCCC1=O)NC(=O)Nc1cnc2c(cnn2C(C)C)c1 +COc1cccc(SCC(=O)N(C(C)C)C(C)C)c1 +Cc1nn(C)c2c1C(c1ccc(F)c(Br)c1)CC(=O)N2 +Cn1cc(S(=O)(=O)NCc2cc3ccccc3o2)cc1C(N)=O +COc1ccc(-c2n[nH]cc2C(=O)Nc2ccccc2Cl)cc1 +COc1ccc(CN(C)C(=O)c2cccnc2N2CCCCC2)cc1 +O=C(c1cccc2ccccc12)N1CCC(OCc2ccccc2)CC1 +O=C(NCC1CCC1)c1ccc(F)cc1C#CCO +CN(Cc1cccc(F)c1)C(=O)c1ccc(N)nc1 +O=C1CCSc2ccc(Cl)cc2N1Cc1ccc(F)cc1 +Cc1noc(C)c1S(=O)(=O)N(CC(N)=O)CC(C)C +CCN(CC)C(=O)N1CCN(C(=O)N(CC)CC)CC1 +Cc1noc(C)c1S(=O)(=O)NCCCSc1ccc(F)cc1 +Cc1cc(C)n(-c2ccc(=O)n(CC(=O)N3CCC(C)CC3)n2)n1 +COc1ccccc1CC1CCCN(C(=O)Cc2cc(C)on2)C1 +CNC(=O)CNS(=O)(=O)c1cc(Cl)ccc1Cl +CCNC(=O)N1CCN(c2c(C)nn(-c3ccccn3)c2C)CC1 +Cc1noc(C)c1CN(C)C(=O)C1(c2cccc(F)c2)CCOCC1 +Fc1cccc(-c2nnc3sc(-c4cccn5nnnc45)nn23)c1 +CN(C)C(=O)CN(C)C(=O)CCCSc1ccccc1 +COCCN1CCN(C(=O)NCCc2ccc(C)cc2)CC1=O +O=S(=O)(c1cc(F)cc(F)c1)N1CCCC(c2cn[nH]c2)C1 +Nc1cc2c(c(COc3ccccc3Br)c1)OCOC2 +Cc1ccc(CCC(=O)N2CCC(CC(N)=O)CC2)c(C)c1 +Cc1ccc(OC2CCN(C(=O)Nc3cnccc3C)CC2)cc1 +Cc1cccnc1NC(=O)c1c(C)oc(C)c1Br +CCCCN(CC)c1cc(C)nc(-c2ccncc2)n1 +COc1ccc(F)c(C(=O)NC(C)c2ccccc2)c1 +Nc1ccccc1OCCc1nnc2ccccc2n1 +COc1ccc(Cc2nc3ccccn3c2C#N)cc1OC +Cc1ccc(CNC(=O)N(C)Cc2ccncc2)c(N(C)C)c1 +Cc1cc(=O)[nH]c2cc(NC(=O)CC3CCCC3)ccc12 +COC(=O)c1ccc(OCc2ccccc2F)c(OC)c1 +CCc1cnc2c(c1NCCOC)c(=O)n(C)c(=O)n2C +Cc1cc(C)c(NC(=O)Cn2c(C)csc2=O)c(C)n1 +CCn1c(=NC(=O)CCCOC)[nH]c2cc(C)ccc21 +CN(Cc1ccc(C#N)cc1)C(=O)c1ccc(CNC(N)=O)cc1 +COc1cccc(CNC2Cc3ccccc3C2)c1 +O=C(Cc1ccccn1)c1cc(F)ccc1Br +COC1CCCC1OC(=O)Cc1ccc(F)cc1 +Cc1csc(C(C)(C)NC(=O)c2ccc(-n3ccnn3)cc2)n1 +Cc1nccc(C(=O)N2CCCC3CCCCC32)n1 +CN(C(=O)CCc1ccc(F)cc1)C1CCN(CC(F)(F)F)C1=O +Cc1nnc(SCc2nnnn2-c2ccccc2)s1 +CC(=O)Nc1ccc(C(=O)COC(=O)c2cccc(C)c2O)c(F)c1 +Cc1nnc(SCCC(=O)Nc2cccc(C(F)(F)F)c2)s1 +Cc1ccc(OCCCC(=O)Nc2ccc3c(c2)OCCO3)cc1 +COc1cccc(C(=O)NCc2c[nH]nc2C)c1O +Cc1nc(NCc2ccccn2)c(N)c(OCC(C)C)n1 +CC(C)NC(=O)CNC(c1c(F)cccc1F)C(F)(F)F +CCc1nnc(NC(=O)c2cc(-c3ccccc3)[nH]n2)s1 +CN1CCN(Cc2ccccc2Cl)CCC1=O +CCn1cc(C(=O)NC2CCN(c3ccccc3F)CC2)cn1 +O=C(NCC(O)c1cccs1)Nc1ccc(F)cc1 +COC(=O)NCC1CCN(C(=O)c2ccoc2)CC1 +c1n[nH]c(SCc2ccc(CSc3ncn[nH]3)cc2)n1 +O=C(NCc1csc(-c2ccccc2)n1)c1ccon1 +CCc1cccc2c1N(C(=O)c1ccc(CNS(C)(=O)=O)o1)CC2 +COc1ccc(-c2nnc(CC(=O)NCC(C)C)o2)cc1 +Cc1ccc(OC2CCN(C(=O)OC(C)(C)C)C2)nn1 +CCCOc1ccc(CNC(=O)NC2CCCC2)cn1 +Cc1cc(NC(=O)c2ccccc2Cn2cncn2)c2ncccc2c1 +CCC(C)n1c(=O)n(C)c(=O)c2c1nc(NCCCO)n2C +Cc1nn(C)c(C)c1C1COCCN1C(=O)c1n[nH]c2ccccc12 +CSc1ccccc1NC(=O)c1cccc(NS(C)(=O)=O)c1 +Cc1cccc(N2CCN(C(=O)c3c[nH]c4cccc(F)c34)CC2)c1 +NC(=O)C1CCCN(C(=O)Cc2ccc(N3CCCC3=O)cc2)C1 +Cc1ccc2ncc(C(=O)Nc3ccc(Cl)cc3F)c(=O)n2c1 +COc1cc(S(=O)(=O)n2cnc(C)c2)c(OC)cc1C +Cc1ccc(NC(=O)COc2cn(-c3ccccc3)nn2)cc1 +CC(=O)Nc1ccc(NC(=O)NCCCC(N)=O)cc1 +CC(C)CS(=O)(=O)N1CCC(c2ccsc2)CC1 +Cc1noc(CCNC(=O)C2(c3ccc(F)cc3)CCCC2)n1 +CCCCN(C(=O)C1CN(C(=O)c2cc(C)on2)C1)c1ccccc1 +CN(C(=O)c1ccc2c(=O)n(C)c(=O)n(C)c2n1)C1CCCCCC1 +NC(=O)c1ccc(CNC(=O)CCc2ccccc2)o1 +Cn1c(C(=O)NCc2ccccn2)cc2c(=O)n3ccccc3nc21 +O=C(NCCCN1CCCC1=O)c1cc2scnc2[nH]1 +COc1cc(-c2ccc(Cl)c(C#N)c2)ccc1O +Cc1cccc(C(=O)NCCNc2ncccn2)c1C +CCCCN(C)S(=O)(=O)Nc1ccccc1-c1nc(C)n[nH]1 +Cc1cc(C(=O)NC2CC3CC2C2CCCC32)no1 +COc1ccc(C)cc1CNCc1scnc1C +CC1CCCCN1C(=O)CSc1ncccc1C#N +OC(CNCc1cnc(N2CCOCC2)nc1)c1ccc(F)cc1 +CC(C)C(NC(=O)Nc1cnn(CC(N)=O)c1)c1ccc(Cl)cc1 +Cc1ccccc1-n1ncc(C(=O)N(C)CC(=O)NC(C)C)c1C +COc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1OC +O=C(CCc1ccco1)Oc1ccc(NC(=O)c2ccccc2)cc1 +COc1ccc(C(=O)c2ccco2)cc1Br +CC(O)CN(C)C(=O)c1ccc(COC(C)C)cc1 +Cc1ccc(S(=O)(=O)N2CCC(Oc3cccnc3)C2)s1 +CC(C)OC(=O)CCCC(=O)c1cc(F)ccc1F +Nc1ccccc1NC(=O)CN1C(=O)COc2ccccc21 +CCOC(=O)N1CCC(NC(=O)Cc2ccc(F)cc2)CC1 +CC(=O)N1CCCN(C(=O)c2cc3ccccc3c(=O)[nH]2)CC1 +NC(=O)COC(=O)c1ccc(CNC(=O)c2cccs2)cc1 +Cn1cccc1C1COCCN1C(=O)c1ccc(F)cc1F +Cc1cccc(C(=O)NCc2cn(-c3ccccc3)nn2)c1C +Cc1nn(-c2ccccc2)c(C)c1C(=O)NCc1cnn(C)c1 +COc1ncccc1CNC(=O)NCC(O)c1ccc(F)cc1F +COc1ccccc1CNC(=O)c1nn(-c2ccccc2)c2c1CCC2 +Cn1c(C(=O)OCC2CC(=O)N(C3CC3)C2)ccc1-c1ccccc1 +Cc1ccc(OCC(=O)N2CCOC(C)C2)cn1 +CCOc1cc(C)c(S(=O)(=O)Nc2ncccc2C)cc1C +N#Cc1cccc(CSc2nccn2C2CC2)c1 +N#CC(Cc1ccc2c(c1)OCO2)c1ccccc1F +Cc1cc(C)c(NC(=O)c2sc(-c3cccnc3)nc2C)c(C)c1 +Cc1cc2nc(CO)n(Cc3ccc(F)cc3)c2cc1C +CC(C)(C)c1ccc2c(c1)CNCC2C(=O)N1CCCC1 +Cc1cccc(C2(C(=O)NCC(=O)N(C)C)CC2)c1 +Cc1nc(COc2ccc(F)cc2)sc1C(=O)NCC(F)(F)F +CCC(NC(=O)N(C)CCOC)c1ccc(Br)cc1 +Cn1c(-c2ccc(=O)[nH]c2)nc2cc(Cl)c(Cl)cc21 +O=C(NCc1ccccc1Cl)c1ccc(-c2ccco2)[nH]c1=O +O=C(NC1CCCC1)c1cccc(-n2ccnc2)c1 +CCOc1ccc2c(c1)sc1nc(C(=O)OC)cc(=O)n12 +Cc1ccc(NS(=O)(=O)c2cccc(C(F)(F)F)c2)nc1 +C#CCNC(=O)COc1ccc(Br)cc1F +O=C(CCc1cc(F)ccc1Br)N1CCC(CO)CC1 +C=CCNC(=O)Nc1cc(N2CCOC2=O)ccc1F +CCOC(=O)N1CCN(CCn2nc(C)cc2C)CC1 +O=C(c1cccc(OC(F)F)c1)N1CCN(c2ccccc2)CC1 +NC(=O)NCCC(=O)Nc1ccc(C(=O)NC2CCCCC2)cc1 +COCCN1CC2CN(C(=O)C3CC3)CCN2C1=O +CCc1nnc(NC(=O)CC2Sc3ccccc3NC2=O)s1 +Cc1noc2ncnc(Nc3ccc(F)c(Cl)c3)c12 +COc1cccc(CCNC(=O)c2cc(CC(C)C)n[nH]2)c1 +CCCn1c(C)nnc1SC(C(N)=O)c1ccc(C#N)cc1 +CS(=O)(=O)Nc1nc(CC(=O)NCCCO)cs1 +CCOc1cc2c(c(Cl)c1O)C(C1CC1)NCC2 +CC(C)C(=O)N1CCC(NC(=O)c2csc(-c3ccco3)n2)CC1 +CC1CCN(C(=O)CCCC(O)c2ccccc2)CC1 +COc1ccc(Br)c(C(=O)NCc2nc(C)cs2)c1 +O=C(Cc1ccc(F)cc1)NCC(O)(c1ccccc1)C(F)(F)F +CC(C)(C)c1cccc(OCCN2CC(C#N)CC2=O)c1 +CCN1CC(CO)OC1c1ccc(Br)cc1 +Cc1nc(CCCNC(=O)c2cccc(C(F)(F)F)c2F)n[nH]1 +Cn1cnnc1CNC(=O)C1(c2ccc(Br)cc2)CCC1 +CC(C)c1nc(CN2CCOC(Cn3cccn3)C2)cs1 +COc1cccc(CCc2cc(C)[nH]c(=O)c2C#N)c1 +Cc1cc(OCC(=O)NCc2sccc2C)nnc1C +COc1ccccc1NC(=O)NCCCC(C)(C)C1OCCO1 +O=C(NC1CCC2(CC1)OCCO2)N1CCOCC1C1CC1 +Cc1cnc(CNC(=O)c2c[nH]c3cccc(F)c23)s1 +Cc1noc(C)c1CN1CCN(C(=O)CCc2cnn(C)c2)CC1 +OC(CCc1nccs1)c1ccc2c(c1)CCC2 +C=CCN1C(=O)c2oc3cc(C)c(C)cc3c(=O)c2C1c1cccnc1 +C=CCSc1nnc2c3cnn(-c4ccccc4)c3ncn12 +COc1cc(CNc2ncc(F)c(N3CCCC3)n2)ccc1O +COc1ccc(C(=O)NCC(=O)Nc2nccs2)cc1 +COc1ccc2c(c1)CCc1c(C(=O)NCc3ccc(C)cc3)n[nH]c1-2 +Nc1cccc(NC(=O)CCCn2cc(Cl)ccc2=O)c1 +CN(C)c1nc(N)nc(CSc2nnnn2-c2ccc(O)cc2)n1 +Nc1nc(C2CC2)ncc1C(=O)NCc1ccccc1F +Cc1ccn(CC(=O)NCC2CCCO2)c(=O)c1C#N +Cc1ccnc(NS(=O)(=O)c2ccc(C)cc2C)c1 +COc1cc(C)c(Cl)cc1-c1cn2cc(N)ccc2n1 +Clc1ccc(CCNc2ncnc3[nH]ncc23)cc1 +CCc1ccc(CCC(=O)N(C)Cc2nc3ccccc3c(=O)[nH]2)cc1 +Cc1nccc(CNC(=O)C2(c3cccc(Cl)c3)CC2)n1 +O=C(COc1ccc(F)c(F)c1)NC1CCCc2ccccc21 +C=CCN(CC=C)S(=O)(=O)c1cc(F)ccc1F +CCCCCNC(=O)c1onc(-c2cccc(C)c2)c1N +CNC(=O)CN1CCN(C(=O)Cc2coc3c(C)c(C)ccc23)CC1 +CC(C)(C)NS(=O)(=O)c1cccc2c1CCNC2 +COc1ccc(-n2nnc(C(=O)NCCO)c2C(C)C)cc1 +O=C(NCc1cccnc1)Nc1ccc(OCC(F)(F)F)nc1 +CC(C)CC(=O)N1CCC(Oc2nc3ccccc3s2)CC1 +COC(=O)CN(C)c1nccn(C(C)(C)C)c1=O +O=C(CCNC(=O)c1cc2cc(Cl)ccc2o1)Nc1ccccn1 +COc1ccc(C(=O)NC(C(N)=O)c2ccccc2)cn1 +Cc1cc(C)c(CNC(=O)CNC(=O)c2cccs2)c(C)c1 +CCC(Sc1ncnc2c1cnn2C)C(=O)c1ccc(OC)cc1 +CC(C)N1CCc2ncn(C(C)C)c2C1C(=O)NCc1cccs1 +Cn1cccc1C(=O)OCC(=O)N(C1CCCC1)C1CC1 +Cc1cc2oc(C(=O)NCc3ccncc3)cc(=O)c2cc1C +Cc1cc(C(C)(O)CNC(=O)c2cc3ccccc3c(=O)[nH]2)c(C)o1 +Cc1ccc(CN2Cc3nnn(C)c3C(COCC(=O)N(C)C)C2)o1 +COc1ccc(C(C)COC(=O)c2ccc3nncn3c2)cc1 +COCC(=O)N1CCC2(COCc3cnc(N4CCOCC4)nc32)C1 +COc1ccc2c(cnn2CCC(=O)NCC(C)C)c1 +CCNC(=O)c1cccc(NC(=O)NCC(=O)Nc2ccccc2)c1 +CN(CCC(F)(F)F)C(=O)C1CC(=O)N(Cc2ccco2)C1 +COCC(=O)N1CCC(Cc2cnc3ccccc3c2)C1 +CC(CNC(=O)c1cccs1)Oc1ccccc1 +Cc1cc(Cl)ccc1NC(=O)N1CCNC(=O)C1 +CCN(CC)C(=O)c1nnn(Cc2ccccc2)c1OC +CNC(=O)c1ccc(NC(=O)CCc2c(C)nc(C)[nH]c2=O)cc1 +O=C(NC1CC1)c1ccc(CNC(=O)C2CCC2)cc1 +COC(=O)Nc1cccc(NCC(=O)NC2CCCCC2)c1 +Cc1csc(C(NC(=O)NCC(=O)NCc2ccco2)C2CC2)n1 +Cc1nc2cc(Cc3c(O)n[nH]c3N)ccc2n1C +Cc1ccc(C)c(NC(=O)CCCCCNC(N)=O)c1 +CC1CCCCN1C(=O)Cn1nnc2ccccc2c1=O +COC(=O)CCCN1C(=O)C(C)Nc2cc(C)ccc21 +COC(=O)c1ccccc1NC(=O)c1cc(NC(C)=O)ccc1F +Oc1cc(N2CCCCC2)cc(N2CCCCC2)c1 +CCC12CCCN3CCC4=C(C31)N(Cc1ccccc14)C(=O)C2 +CN(Cc1ccccn1)C(=O)CCc1cnn(C)c1 +CCC(C)Oc1cccc(NC(=O)c2ccco2)c1 +CCc1cnc(CN(C)C(=O)NCc2nc(C)cs2)s1 +CC(C)Oc1cc(Br)cn(CCO)c1=O +NC(=O)c1ccc(CN(C(=O)Cc2cccs2)C2CC2)cc1 +CN(C)C(=O)c1ccc(C(=O)N(C)C)c(OC2CC2)c1 +CC(=O)c1cccc(NC(=O)c2cnn(-c3ccccc3)n2)c1 +CCc1nc(CCNC(=O)N2Cc3ccccc3C2)sc1C +Cc1cc(C)cc(OCCN(C)C(=O)NC2CC2)c1 +COc1ccc(CC(=O)c2cc(OC)c(O)cc2O)cc1 +CCC(C(=O)NCCc1cc(C)no1)c1ccccc1 +CN(C(=O)c1ccn2cncc2c1)c1ccccc1C#N +CC(=O)N1CCC(NC(=O)c2ccc(Br)cc2O)CC1 +CCc1cccc(CC)c1NC(=O)N1CCN(CCOC)C(=O)C1 +Cc1cnc(NC(=O)c2ccnc(-n3cncn3)c2)s1 +O=C(Cn1nc(-c2ccoc2)oc1=O)NC1CCCCC1 +CCCOc1ccc(OC(=O)c2cc(C(N)=O)cs2)cc1 +COCc1cc(C)nc(SCC(=O)Nc2ccccc2)c1C#N +Cc1cccc(C(=O)Nc2n[nH]c(-c3cccc4ccccc34)n2)n1 +CNC(=O)C(C)NC(=O)N1CC2CC3CC(C2)CC1C3 +COC(=O)CNc1ccc(S(=O)(=O)NC(C)C)cc1 +COC(=O)C1=C(C)NC(=O)CC1c1cc(Br)ccc1F +CCN(Cc1cccc(F)c1)S(=O)(=O)Cc1noc2ccccc12 +Fc1ccccc1C1(CNCc2cnc(N3CCOCC3)nc2)CC1 +CC(C)n1c(N)nnc1SCc1ccc(Br)cc1 +N#Cc1ccc(C(=O)NCC(=O)NC2c3ccccc3CC2O)cc1 +CC(C)Cc1ncc(CN2CCOC3(CCCC3)C2)s1 +CCc1cccc(NC(=O)Cn2nc3c4ccccc4ncn3c2=O)c1 +CC(C)CN(CC(C)C)C(=O)Nc1ccc(F)c(C(N)=O)c1 +O=S(=O)(Cc1ccon1)N1CCN(Cc2cccnc2)CC1 +Cc1ccc(N(C)C(=O)c2ccc(-n3ccnn3)cc2)c(C)c1 +COc1cc(C)c(CN(C)C(C(N)=O)c2ccccc2)cc1OC +C=CCNC(=O)CSc1nnc2c3cc(F)ccc3n(C)c2n1 +COc1ccc(CCNS(=O)(=O)Cc2ccc(F)cc2)cc1 +Cc1ccc(C(=O)N(CCO)C(C)(C)CO)cc1C +CCCS(=O)(=O)N1CC=C(c2c[nH]c3ccc(OC)cc23)CC1 +Cc1ccsc1C(=O)Nc1ccc(F)c(F)c1 +COc1ccc2cc(CNC(=O)NCCN3CCOCC3)ccc2c1 +CCC(O)CN1CCN(C(=O)C2CC2c2ccc(C)s2)CC1 +CCN1CCOC(=O)C1CC(=O)Nc1ccc(Cl)cc1 +Cc1cccc(CNC(=O)C2CCN(c3ccc(Cl)cc3)C2=O)c1 +Cc1c(CNC(=O)Nc2ccccc2-n2nccc2C)cnn1C +CC(NC(=O)CNC(=O)C1CCCCC1)c1ccccn1 +O=C(Cn1nc(-c2ccc3c(c2)OCO3)ccc1=O)NC1CCCC1 +COc1ccc(NC(=O)NCCC(C)(C)C)cc1 +CC1CCCC(CNC(=O)CCCCNC(N)=O)C1 +O=C(NCCCc1ccccc1)c1cc(=O)[nH]c2ccccc12 +CN(C(=O)COc1ccc(F)cc1F)C1(C#N)CCCCC1 +O=C(COc1ccc(N2CCCC2=O)cc1)Nc1cccc(O)c1 +Cc1cc2nc(N)nn2cc1-c1ccc(O)c(F)c1 +Cc1nc2sccn2c1CNC1CCCN(c2cccnn2)C1 +Cc1nc(C)c(CC(=O)NC(C)C23CC4CC(CC(C4)C2)C3)c(=O)[nH]1 +CNC(=O)CNS(=O)(=O)c1cc(N)cc(C)c1C +COCCc1nc(C2CCOC(C)(C)C2)n(C)n1 +Cc1cc(C)c(C#N)c(SCC(=O)NC(C)(C#N)C(C)C)n1 +COc1ccc(NC(=O)NCc2ccco2)cc1N1CCCC1=O +Cc1nn(-c2ccc(Br)cc2)nc1C(N)=O +COc1ccc(C(=O)NCc2nc(-c3cccs3)no2)cc1OC +O=C(c1coc2ccccc12)N1CCC(Cc2ccccc2)C1 +Cc1cccc(C(C)C)c1NC(=O)NC(C)c1nc2ccccc2[nH]1 +CCN(CC(C)C#N)C(=O)CN1CC(C)OC(c2ccccc2)C1 +CCC(=O)Nc1cc2nn(-c3ccc(F)cc3)nc2cc1C +CCOC1CCN(C(=O)CCc2ccc(OC(F)(F)F)cc2)CC1 +Cc1cc(C)cc(C2(C(=O)N3CCC(N4CCCC4=O)CC3)CC2)c1 +CC(CN1CCOCC1)NC(=O)CCc1nc2ccccc2s1 +Cc1ccc(C)c(NCC(=O)N(C)Cc2ccccc2)c1 +CCOC(=O)NCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +CC1OCCN(Cc2cccc(-c3ccccn3)c2)C1C +O=C(Nc1ccc(-c2csnn2)cc1)c1ccc2cc[nH]c2c1 +CC(=O)NC(C)C(=O)NCCc1c[nH]c2ccccc12 +CCCn1nc(C)cc1-c1nn2c(C(C)C)nnc2s1 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(CCO)cc1 +Cc1nn(C(C)C)c2cnn(CCNC(=O)C3CCCO3)c12 +Cc1ccccc1S(=O)(=O)N1CCC(c2cc(N)on2)CC1 +Cc1ccc(F)c(C(=O)Nc2ccccc2C(=O)NCCC(N)=O)c1 +CCOC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1ccc(Cl)cc1 +O=C(CS(=O)(=O)c1ccccc1F)NCC(F)(F)F +Cc1ccc(OCc2nc3ncc(C)cc3[nH]2)cc1 +NC(=O)C1CCCCN1C(=O)c1ccc(F)c(F)c1 +COc1cc(OC)cc(C(=O)Nc2ncnc3c2CCC3)c1 +C#CCOCC1CCCN(C(=O)c2cccnc2)C1 +COc1ccccc1Nc1nnc(SCC(=O)NC(C)C)s1 +Cc1cc(OCC(=O)NCc2nncn2C)c(C(C)C)cc1Cl +O=C(Cc1n[nH]c2ccccc12)N(CCc1ccccc1)C1CCOC1 +COC(=O)CN1CCN(c2ccc(Cl)c(Cl)c2)CC1 +CC(=O)N1CCC2(CCc3ccc(-c4cccnc4)cc32)CC1 +CC(NS(C)(=O)=O)C(=O)NC(C)c1ccc(Cl)c(Cl)c1 +Cc1ccc(C(=O)NC(C)c2ccc(-n3ccnc3)cc2)c(=O)[nH]1 +Cc1cccc(-n2nnc(C(=O)N3CCOCC3)c2C(C)C)c1 +COc1nc2ccccc2nc1C(=O)Nc1ccc(Cl)cn1 +c1cncc(CN2CCCCC2c2nc3ccccc3[nH]2)c1 +Cc1ncsc1CNc1cccc(Br)c1 +Cc1nn(-c2ccccc2)nc1C(=O)N(C)CC(N)=O +CC(=O)c1ccc(F)c(NC(=O)COc2cccc(C)c2)c1 +Cn1cc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c(C(C)(C)C)n1 +Cc1cccc(-n2ncc3c(=O)n(CC#N)cnc32)c1C +CCOc1ccc2oc(=O)c(C#N)c(N(CC)CC)c2c1 +O=C(NC1CC1)C1C=CCN1C(=O)c1ccc(F)cc1F +Cc1ccc(CNc2ncnc3c2CCN(S(C)(=O)=O)CC3)o1 +CC(C)n1nnc(-c2ccc(C(=O)Nc3cccnc3)cc2)n1 +CCOC(=O)CNC(=O)c1ccc(OC)c(OC)c1 +COc1ccc(C)cc1CC(=O)N1CCC(=O)CC1 +CCCc1cc(=O)n2c(n1)SCC2CC(=O)N1CCCCC1CC +Cc1cc(C(F)(F)F)nn1CC(=O)N1CCCc2ccccc21 +COc1cc2nc3n(N)c(=O)cnn3c(=O)c2cc1OC +COCCN(Cc1ccco1)C(=O)c1ccncc1F +COC1(C)CC(NC(=O)N(C)C(C)c2ccncc2)C1(C)C +NC(=O)Nc1ccc(C(=O)Nc2cccc(F)c2)cc1 +Cc1cc(C)nc(NC(=O)NCCCSc2nncn2C)n1 +Nc1c(NCc2ccc(Cl)cc2)nc[nH]c1=O +Cc1ccccc1OCC(=O)Nc1cc(C(N)=O)cc(C(N)=O)c1 +O=C(Cc1ccccc1)N1CCN(c2nc3cccnc3s2)CC1 +CC(C)(C)C(=O)CNC(=O)c1ccc(COc2ccc(F)cc2)o1 +O=C(OCc1ccccc1)N1CCCC(CNC(F)(F)F)C1 +O=C(COC(=O)c1ccoc1)Nc1ccccc1C(F)(F)F +COc1ccc(OC)c(C(=O)NC2CCN(c3nnnn3C)CC2)c1 +COc1cc(Br)c2cc3n(c2c1)CCC3=O +CC(=O)N1CCC(NC(=O)c2nccnc2N)CC1 +Cn1cc(N2CCN(C(=O)c3cn(C)nc3C(C)(C)C)CC2=O)cn1 +Cc1ccccc1Cn1cnc2oc(-c3ccncc3)nc2c1=O +CCn1cc(C(=O)Nc2cccc(Cl)c2N(C)C)cn1 +Cc1cc(NC(=O)c2ccc(=O)n(Cc3ccccc3)n2)on1 +Clc1cccc(NCc2ccncc2)c1Cl +CC1CN(C(=O)CCc2nc3ccccc3s2)CCO1 +Cc1nc(C(C)NC(=O)NCCOc2ncccc2Cl)cs1 +COC(=O)Cc1csc(Nc2ccc(C)c(N)c2)n1 +CCOC(=O)C1CCCN(c2ccccc2CO)C1 +CCOc1cc(OCC)cc(C(=O)Nc2ccc(C#N)cc2)c1 +CN(CCC#N)C(=O)COc1ccccc1Cc1ccccc1 +Cc1cc(C)cc(NC(=O)CSc2nnc(C(C)C)n2N)c1 +O=C(CCOc1ccccc1)Nc1ccn(-c2ncccc2Cl)n1 +Cc1cc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)no1 +COc1ccc(CNC(=O)C2CC(=O)N(C)C2c2cccnc2)cn1 +CCOCCC(=O)Nc1ccc(-c2nc(C)cc(=O)[nH]2)cc1 +COc1cc2c(cc1C(=O)Nc1ccc(C(C)=O)cc1)OCCCO2 +COc1ccc(C(=O)NCCS(N)(=O)=O)cc1N +O=C(Nc1nnc(-c2ccccn2)s1)c1nccc2ccccc12 +O=S(=O)(c1cccc(-c2cn3ccccc3n2)c1)N1CCOCC1 +CC1CN(C(=O)CCC(=O)CCC(=O)c2cccs2)C(C)CO1 +CCCN1CC(C(=O)NCC2CCCO2)CC1=O +Cc1ccc(-c2cc(C(=O)N3CCCC(C(N)=O)C3)on2)cc1 +COC(=O)C(C)CNC(=O)Nc1ccc(N(C)C(C)C)c(F)c1 +CC(C)CCOC1CCCCC1NC(=O)C1OCCC1C +CCOC(=O)c1cnn2ccc(NC(=O)Cc3ccc(F)cc3)cc12 +CC1CCCCN1C(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CC(C)(C)c1nnc(SCCOc2ccccc2F)n1N +CCOc1cc2c3c(c1)C1(OCCO1)C(=O)N3C(C)(C)CC2C +O=C(NCc1cccs1)c1cccn2c(=O)c3ccccc3nc12 +COc1ccc(COC(=O)c2scnc2C2CC2)cc1OC +Cc1ccc(C)c(Oc2ccc(CNS(C)(=O)=O)cn2)c1 +Cc1ncnc2c1CN(C(=O)c1cccc(N(C)C)c1)CC2 +CC(C)(CO)NC(=O)c1sccc1-c1ccccc1 +CC(=O)Nc1ccc(CCNC(=O)Nc2ccncc2F)cc1 +Cc1cccc(OCCN2C(=O)C(C)(C)Oc3cc(N)ccc32)c1 +Cn1c(N)nnc1SCc1ccc(Br)cc1 +C#CCOc1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1 +CCOC(=O)c1c[nH]c2ccc3nc(C)sc3c2c1=O +CC(C)(C)NC(=O)Nc1ccccc1C#CCCO +Cc1ccccc1C(=O)Nc1ccc(N2CCOCC2)nc1 +CCn1c(C)cc(NCCC2=CCCCC2)cc1=O +CN(C)C(=O)Cc1ccc(NC(=O)c2cccc(Cl)c2)cc1 +Cc1ccccc1OCC(=O)Nc1ccc2c(c1)C(=O)NCCO2 +Cc1ccc2oc(C(=O)Nc3ccc(S(C)(=O)=O)cc3C)cc2c1 +Cn1cnnc1-c1ccc(NC(=O)COc2ccccc2)cc1 +Cc1nnc(NC(=O)c2cc(NC(=O)c3cccs3)n(C)n2)s1 +CCc1nc(CC(=O)Nc2cc(F)ccc2-n2ccnc2C)cs1 +CCc1cn[nH]c1C1CCCN(Cc2c[nH]nc2-c2ccccc2)C1 +Cc1noc(C)c1COC(=O)CCCc1c[nH]c2ccccc12 +CC1CCc2sc3nc(SCC(N)=O)n4ncnc4c3c2C1 +COc1ccc(C)cc1NC(=O)CNc1nc(C)nc2oc(C)nc12 +O=C(NCC1CC1)C1CCN(c2ccc(Br)cc2)C1=O +COC(=O)c1ccc(CSc2nnc(C(C)(C)C)n2N)o1 +Cc1nn(C)c2ncc(C(=O)OCc3nc(-c4ccccc4)no3)cc12 +CCCN(CCO)C(=O)NC1CCCN(Cc2ccccc2)C1=O +CCC1CCCCN1S(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +CC(C)(C)Sc1ccc(NC(=O)C2CCN(C(N)=O)CC2)cc1 +O=C(Cc1n[nH]c(=O)c2ccccc12)NCCc1ccco1 +COc1ccc(O)c(C(=O)OCC(=O)Nc2ccc(SC)cc2)c1 +CC(C)(C)c1ccccc1OCCC(=O)N1CCC(O)CC1 +CCc1nnc(NC(=O)NCc2ccnc(-n3cccn3)c2)s1 +Cc1cnc(Cn2ccnc2-c2ccc(C#CC(C)(C)O)cc2)cn1 +Cc1ccccc1CNC(=O)COC(=O)c1cccc(C#N)c1 +COCc1ccccc1CNC(=O)NC(C)c1c(C)noc1C +COc1ccc(-c2noc(CC(=O)N(C)c3ccccc3F)n2)cc1 +CCS(=O)(=O)c1ccccc1C(=O)OCc1cc(C)on1 +CC(C)CC(=O)Nc1ccc2c(c1)CN(C(=O)C1CC1)CC2 +O=C(NC1CCc2ccccc21)C1COc2ccc(F)cc2C1 +CCn1ncc(CNc2ccc(C(F)(F)F)cc2)c1C +CC(=O)NCCNC(=O)Nc1cn(C)c2ccccc12 +Cc1cc(CNc2cc(S(=O)(=O)N3CCCCC3)ccc2C)no1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCCc1ccc(Cl)cc1 +O=C(NCC1CC12CCCc1ccccc12)NC1CCCNC1=O +Cc1c(C(=O)N2CCOCC2)nc2cc(Cl)ccn12 +Cc1ccc(OCc2nc(C)c(C(=O)OC(C)C(N)=O)s2)cc1 +CC(C)(C)c1noc(CCCC(=O)NCc2cc(F)cc(F)c2)n1 +NS(=O)(=O)c1cccc(NC(=O)CCc2ccc3c(c2)OCO3)c1 +CC(Oc1ccc(-c2ccccc2)cc1)C(=O)N1CCNC(=O)C1 +Cc1cccc(C(C)C)c1NC(=O)CSc1nnc(C)n1N +CCc1nnc2sc(Cc3noc4c(C)cccc34)nn12 +CC(C)C1CN(c2ncccc2C#N)CCC(=O)N1CC1CC1 +COc1ccc(NC(C)=O)cc1NC(=O)COc1ccc(F)cc1 +COc1ccc(NC(=O)CCOc2cccc(C)c2C)cn1 +COc1ccc(C(C)=O)cc1NC(=O)c1cccc(Cl)c1 +CC1C(=O)NCCN1C(=O)NCc1ccccc1N1CCCCC1 +Cc1cc(C(=O)NCC(C)C)nc2cc(-c3ccccc3)nn12 +COc1ccc(C)cc1S(=O)(=O)N=c1cccc(C)[nH]1 +CCN(CC1CC1)C(=O)c1ccc(NC(=O)C2CC2)s1 +Cn1cc(NS(=O)(=O)c2ccc(N)cc2Cl)cn1 +O=C(NCCC1CCCCC1)N1CCN(C(=O)c2ccco2)CC1 +N#Cc1ccc(C(=O)Nc2cnn(-c3ccccc3F)c2)cc1 +CCCn1ccc2cc(NC(=O)N3CCCC(C)C3CO)ccc21 +Cc1cccc(NC(=O)C2CCN(c3cnn(C)c(=O)c3)CC2)c1C +CN(Cc1cccnc1Oc1ccccc1)C(=O)c1cnccn1 +CCc1c(C(=O)NCc2cccc(OC)c2)cnn1Cc1ccccc1 +Cc1ccc(NC(=O)C(C)Oc2cccc(C#N)c2)cc1F +CCCC1CCC(NC(=O)c2cc(C)nn2C)CC1 +CC(C)(C)C(=O)CSc1nncn1-c1cccc(Cl)c1 +NC(=O)c1ccccc1NC(=O)c1ccc(N)cc1 +Cc1ccc(-c2noc(CCC(=O)OCC#N)n2)cc1 +COCC(C)OC(=O)c1ccc(-n2cccn2)cc1 +Cn1ccc2nc3oc4ccccc4c(=O)c3cc2c1=O +Cc1cc(NC(=O)Cn2cccc(-c3nc(C4CC4)no3)c2=O)no1 +COc1ccc(C(=O)N2CCOC3CCCCC32)cc1 +Cc1cc(Sc2ncccn2)ccc1NC(=O)c1ccc(=O)[nH]c1 +CC(C)(C)CCNC(=O)c1cc(-c2ccccc2)[nH]n1 +Cc1nc(-c2c[nH]c(C(=O)Nc3nc4c(s3)CCC4)c2)cs1 +CC(=O)N1CCN(C(=O)COc2cc(Cl)cc(Cl)c2)CC1 +O=C(Nc1ccccc1)c1ccccc1NC(=O)C1CCCO1 +O=C(Nc1ccncc1)N1CCC1c1ccccc1 +CC(Cc1ccccc1F)NC(=O)c1ccccc1 +COc1cc2c(cc1OC)CN(C(=O)Cn1ccc(=O)[nH]c1=O)CC2 +CNc1c(F)cc(C(=O)NCCCC(N)=O)cc1F +COc1cc2c(c(OC)c1Br)C(C)NCC2 +Cn1cc(C(=O)Nc2cccc(F)c2F)c(C(C)(C)C)n1 +Cc1cc(C)c(CCNC(=O)CN2CCOC(C(N)=O)C2)c(C)c1 +CC1CCCN(C(=O)Nc2ccc(OCC(=O)N(C)C)cc2)C1 +CCNC(=O)N(Cc1ccc(C)cc1)Cc1ccco1 +O=C(NCc1ccc(C(=O)N2CCCC2)cc1)c1cc2cccnn2c1 +CCc1nc(CC(=O)Nc2cc(-c3nnco3)ccc2C)cs1 +CC1(C)COCCN1C(=O)c1ccc2cc[nH]c2c1 +CN(Cc1cc(Cl)cc(Cl)c1)C(=O)C1CC2CCC1O2 +CCC(C(=O)Nc1cc(C)ccc1Br)N1CCCC1=O +Cn1ncc(Cl)c1-c1nc2c3c4c(sc3ncn2n1)CCC4 +CC(=O)Nc1ccc(O)c(C(=O)N(C)CCC(C)C)c1 +CCCCNC(=O)Cn1c(=O)cc(-c2nc(C)no2)c2ccccc21 +CC(=O)Nc1c[nH]c(C)c1C(=O)NCCCC(C)C +CCCCCc1nnc(NC(=O)NC(C)c2ccncc2)s1 +Cc1cnn(-c2ccc(C(=O)N(CCC(N)=O)c3ccccc3)cc2)c1 +Cc1nc2n(n1)CCN(C(=O)c1cc3c(s1)CCC3)C2 +Cc1cc(C(C)NC(=O)Nc2cnccc2C)c(C)o1 +O=C(NC1Cc2ccccc2C1)C1CCC(Cn2cnnn2)CC1 +NC(=O)Cn1cc(C(=O)N2CCCC(c3nccs3)C2)nn1 +O=C(COC(=O)c1c[nH]c2ccccc12)NCc1cccs1 +COc1ccc(S(=O)(=O)N2CCc3cc(F)ccc3C2)cc1 +COC(=O)c1sccc1S(=O)(=O)NC(C)(C)C +OC1C=C(C2NCCc3c(F)cc(F)cc32)CC(O)C1O +COC(=O)c1cc(C)ccc1NC(=O)CN(C)C(=O)c1ccccc1 +O=C(C1CC1c1ccco1)N1CCC(c2nnc3n2CCC3)CC1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCC(=O)N(C)C)O2 +CCc1nc(CCNC(=O)Nc2cc(F)ccc2OC)sc1C +CCCC(=O)NC1CC(C)(C)Cc2nc(N3CCCC3)ncc21 +O=C(c1cnn(-c2ccccc2)c1)N(Cc1ccncc1)C1CC1 +CCn1nnc2cc(C(=O)Nc3c(C)cccc3C)ccc21 +CC(C)(C)c1cnc(CSc2nnc(C3CC3)n2C2CC2)o1 +COC(=O)C(C)CN(C)Cc1sccc1Br +CNC(=O)CC1C(=O)NCCN1C(=O)Cc1ccc(C(C)C)cc1 +CC1CCCCC1OCCNC(=O)c1ccc(N2CCNC2=O)cc1 +N#CC(C(=O)c1cccc(F)c1)c1nc(=O)c2ccccc2s1 +C(#CCN1CCOCC1)CCCN1CCOCC1 +COCc1ccc(C(=O)N(C)Cc2ccccc2)o1 +CC(=O)NC(C)C(=O)N(CCO)C1CCCCC1 +CCOC(=O)CNC(=O)c1ccc2[nH]c3ccccc3c2c1 +O=C(CCC(=O)c1ccc(Br)cc1)OCC1CCCO1 +CCCCCn1c(C(C)NC(=O)c2ccncc2)nc2ccccc21 +COc1ccc(F)cc1S(=O)(=O)N1CCCC(C(N)=O)C1 +Cc1cccc(NCc2cc(=O)oc3cc4c(cc23)CCC4)c1C(N)=O +COc1ccc(C(C)C)cc1C(=O)CNC(=O)C1CC1 +O=C(c1cccnc1)N1CCN(C(=O)C2CC2)CC1 +Cc1nc(C)n(-c2ccccc2NC(=O)N(C)C(C)c2ccccc2)n1 +COc1ccccc1CC(=O)Nc1cnc(N2CCCCC2)nc1 +Cc1ccc(CC(=O)NS(=O)(=O)N(C)C)s1 +CCC1COCCN1C(=O)c1ccc(F)cc1Br +CCOc1ccc(CN(C)C(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +COc1ccc(C(C#N)N(C)C(=O)c2ccccc2)cc1OC +CCCn1c(C)nnc1SC(C)C(F)(F)F +Cn1cnnc1C1CCN(C(=O)c2cc(C(C)(C)C)n[nH]2)CC1 +O=C(CN1C(=O)CSc2ccccc21)Nc1ccncc1 +CS(=O)(=O)N1CCc2c(COCc3nccs3)cncc2C1 +NC(=O)CCCNC(=O)c1c[nH]nc1-c1ccc(F)cc1 +N#Cc1cccc(Oc2ccc(NC(=O)N3CCCC3)cn2)c1 +O=C(NCc1ccco1)Nc1cccc(Cl)c1 +CC(Oc1cccc(-c2cccc3cnccc23)c1)C(N)=O +COc1ccc(CCN2Cc3ccc(C#N)cc3C2)cc1OC +O=C(Cn1nnc2c(cnn2-c2ccccc2)c1=O)Nc1ccccc1 +O=C1CCCN1CCC1CN(Cc2ccon2)c2ccccc21 +COC(=O)N1CCC(NC(=O)COc2cccc(C(C)C)c2)CC1 +CCOc1ccc2cc(C(=O)N(CCC#N)CCC#N)[nH]c2c1 +O=C1CCN(C(=O)c2cccs2)c2ccccc21 +C#CCN(Cc1ccccc1Cl)C(=O)CCNC(C)=O +Cc1cc(NC(=O)NCCCn2cccn2)n(Cc2ccccc2)n1 +CC(C)Oc1cc(C(=O)NCc2ccccn2)cc2occc12 +Cc1cc(C(=O)NCCCn2cncn2)c2ccc(F)cc2n1 +C=C(C)COc1ccccc1C(=O)NCC1CC(=O)N(C2CC2)C1 +CSc1cccc(N(C)C(=O)c2c(C)cc(C)[nH]c2=O)c1 +CC(C)N(C)C(=O)c1nn(C(C)C)c(=O)c2ccccc12 +CC(Oc1ccccc1F)C(=O)Nc1cc(N2CCCCC2)ncn1 +COc1ccc(Nc2ccc(C#N)cc2N)cc1OC +CNC(=O)C1CCCN(C(=O)NCc2ccnc3ccccc23)C1 +Cn1ccc(NC(=O)c2ccc3ccccc3n2)n1 +COCCn1cnnc1Cn1cnc(-c2ccccc2)c1-c1ccco1 +CCOc1ccccc1N1CC(C(=O)N(C)C)CC1=O +Cc1cccc(S(=O)(=O)Cc2ccccc2F)c1 +CCc1[nH]c(-c2ccc(OC)cc2)nc1-c1ccncc1 +CC1CN(S(=O)(=O)N2CCCCCC2c2ccco2)CC(C)O1 +CC(C)(C)OC(=O)NC1CCN(c2cnccn2)C1 +COc1ncc(C)cc1NC(=O)COc1cccc2c1OC(C)(C)C2 +CCn1cc(S(=O)(=O)N2CCN(c3cccc(C)c3C)CC2)cn1 +CC(=O)NC(C)(C)c1noc(-c2cc(C)cc(C)c2)n1 +COc1ccccc1-c1n[nH]c(C2CC2)c1NC(=O)C(C)C +CC(CNn1cncn1)Cc1ccc(C(C)(C)C)cc1 +COc1ccc(C)nc1NC(=O)c1cnn(-c2ccncc2)c1C +CCCCn1nc(CC(C)C)nc1C(C)N1CCOCC1 +Cn1c(CSc2ccccc2F)nc2ccccc2c1=O +Cc1c(C(=O)N2CCN(CC(C)O)CC2)oc2c(F)cccc12 +O=C(NCC1COc2ccccc2O1)c1ccnc(-n2cncn2)c1 +CC(C)(C)OC(=O)N1CCCC(NC(F)(F)F)C1 +Cc1cc(=O)n(CCN2CCOCC2)c2ccccc12 +Cc1ccc(CNC(C)C(=O)NCc2ccco2)cc1F +Cc1cc(C)c2c(n1)sc1c(=O)n(CC(=O)OCC(C)C)cnc12 +OCCn1ncc2c(N3CCCC3Cc3ccccc3)ncnc21 +Cc1nc(-c2cccc(NC(=O)Cc3c[nH]c4ccccc34)c2)cs1 +CCCNC(=O)c1cc2c(cn1)[nH]c1ncccc12 +CC(C)(CNC(=O)c1cn(Cc2ccccc2)nn1)c1ccncc1 +CN(Cc1cccs1)C(=O)COc1ccc(-n2cnnn2)cc1 +Cc1cccc(NC(=O)C(C)NC(=O)c2ccoc2)n1 +Cc1cc(C)n2nc(Nc3ccc(S(N)(=O)=O)cc3)nc2n1 +COC(=O)Cn1nc(C#N)cc1-c1cccc(OC)c1 +Cc1ccn(S(=O)(=O)c2ccc(F)c(C)c2)n1 +Cc1ccc(Cn2nccc2NC(=O)c2cccc(-c3ccoc3)c2)o1 +Cc1cc(NC(=O)C(C)S(=O)(=O)c2ccc(Cl)cc2)no1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)N(C)CCC#N +Cc1ccc(N2CCN(S(=O)(=O)N(C)C)CC2)cc1Cl +CC(CC(=O)Nc1ccc2oc(=O)n(C)c2c1)c1ccc(F)cc1 +Cc1cc(NC(=O)Cc2cccs2)c2ncccc2c1 +CCc1ccc(-c2nnn(CC(=O)NCc3cccs3)n2)cc1 +CCCCCc1nnc(NC(=O)N2CCCC(O)C2)s1 +CN(Cc1nc2ccccc2s1)C(=O)Cn1ccc2ccccc21 +O=C(CSc1ccncc1)N1CCCC1c1ccc2c(c1)OCO2 +O=C(Cc1cccnc1)N1CCCCC1CCc1cccs1 +CC(NC(=O)CC1CCCCC1)c1cccc(NS(C)(=O)=O)c1 +CC(=O)c1cccc(OCCCC(=O)Nc2ccc3c(c2)COC3)c1 +NC(=O)c1ccccc1COC(=O)c1ccsc1 +CC(=O)Oc1ccc(-c2cccc(C(=O)N3CCOCC3)c2)cc1 +O=C(c1ccccc1Cl)N1CCN(c2ccccc2F)CC1 +CCNC(=O)Nc1cc(Cl)c(OC)cc1OC +CNC(=O)COC(=O)Cn1c(SC(F)F)nc2ccccc21 +CC(=O)N(CCc1ccccc1)CC(=O)N(C)c1ccc(C)cc1C +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCc1ccc2c(c1)CCC2 +COc1cccc(-c2nn(-c3ccccc3)cc2C#N)c1 +CCCCCNC(=O)NCCc1nc2ccccc2[nH]1 +COc1ccc(CNC(=O)c2cc3cc(OC)ccc3n2C)cc1 +O=C(CCn1cc(Br)ccc1=O)Nc1c[nH]ccc1=O +O=C1OCCC1N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1 +O=C(Nc1cccnc1-n1cncn1)C1COc2ccc(F)cc2C1 +Cc1nc(C(NS(=O)(=O)Cc2ccon2)c2ccccc2)n[nH]1 +CC(C)Oc1ccccc1NC(=O)NC(C)C(=O)NCc1ccco1 +Cc1cc(C)cc(OCCNC(=O)NCC(C)(O)c2ccsc2)c1 +Cc1nc(N(C)Cc2noc3c2CCCC3)c2c(C)noc2n1 +Cc1ncsc1C(=O)NCCc1nc2c(s1)CCCC2 +CC1CC(OC(=O)c2cc(=O)[nH]c3ccccc23)C(=O)O1 +O=C(c1ccc2[nH]ccc2c1)N1CCC(Oc2cccnc2)CC1 +O=C(CCNc1ncccn1)N1CCCC1c1ccsc1 +CCc1sc(C(N)c2ccc(OC)cc2)nc1C +Cc1c(Cl)cccc1NCc1nccn1C(F)F +CCn1cc(NC(=O)C2CC(=O)N(C)C2c2cccc(Cl)c2)cn1 +Cc1ccn2c(=NC(=O)c3cccc(Oc4ccncc4)c3)[nH]nc2c1 +Cc1ncsc1C(=O)N1c2ccc(N)cc2CC1C +CCCOc1c(Cl)cc(C(N)=O)cc1C(C)C +CC(=O)Nc1nc(C(=O)N(C)Cc2ccccc2Cl)cs1 +Brc1cccc(Cc2noc(Cn3cncn3)n2)c1 +CCOC(=O)c1oc2cc(Br)ccc2c1N +CC(=O)c1sc(Cc2nc(O)cs2)nc1C +O=S(=O)(Nc1cccc(O)c1)c1ccc2c(c1)CCC2 +COC(=O)Nc1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +Cc1ccc(-n2nc(CO)c(C(=O)NCc3ccccc3C)n2)cc1 +CC1(C(=O)NCC2CC2)Sc2ccccc2NC1=O +Cc1csc(=O)n1CCC(=O)OCc1nc(N)c2ccccc2n1 +COC1CCCC1OC(=O)c1nc(C)n(-c2ccccc2C(C)C)n1 +CC(Nc1cc(C(N)=O)ccn1)C(=O)N1CCCCC1C +CC1CN(CCNC(=O)NCCc2ccc3c(c2)OCO3)CC(C)O1 +COCCNc1nc(Nc2ccc(C)cc2)c2cnn(C)c2n1 +N#CCCN(CCN1CCOCC1)CC1CCCCO1 +CCCc1ccc(S(=O)(=O)N2CC(c3nc(C)no3)C2)cc1 +O=S(=O)(Cc1ccc(Cl)cc1)N1CCCC2(CCOC2)C1 +CCn1ncc(N)c1C(=O)NCCCn1ncc(Cl)c1C +CCSc1ccc(C(=O)NCc2ccnc(OC3CCC3)c2)cn1 +COc1cccc(CN(C)C(C(N)=O)c2cccc(F)c2)c1OC +Cc1nc(NC(=O)CCC(=O)c2ccccc2)ccc1N +CC1CCc2nc(N)c(C(=O)Nc3ccc(F)cc3)cc2C1 +Cc1ccc2nc(COc3cc(Cl)ccc3C(N)=O)cc(=O)n2c1 +COc1ccc(Oc2cccc(F)c2C(C)O)cc1 +CCN(Cc1nc2cc3c(cc2[nH]1)OCO3)c1ccccc1 +COc1cc(C(=O)N(C)Cc2ccccc2)cc(Cl)c1OC(C)C +O=C(NCc1ccccc1OCC(F)(F)F)C1CCOCC1 +CCC(COC)NC(=O)c1ccccc1-c1nc(C(C)(C)C)no1 +CC(Oc1cccc(N)c1)C(=O)Nc1ccccc1F +O=c1c2ccc(F)cc2ncn1Cc1ccc(Cl)cc1 +COCCNC(=O)c1ccc(COc2ccccc2)cc1 +COC(=O)c1cccc(NCc2ccccc2F)c1 +O=C(CSc1ncnc2ccccc12)Nc1cccc(F)c1 +CC(CCC(C)(C)C)NC(=O)NC1CCN(c2cnn(C)c2)C1=O +Clc1cccc2[nH]c(-c3cnc(N4CCOCC4)nc3)nc12 +O=C(Cn1nnc(-c2cccc(C(F)(F)F)c2)n1)NC1CCCC1 +NC(=O)CN1CCN(C(=O)c2ccccc2-c2ccccc2)CC1 +Cc1csc(CCCNC(=O)Cc2c[nH]c3c(C)cccc23)n1 +CC(=O)N1CCN(C(=O)Cc2csc(-c3cccc(F)c3)n2)CC1 +Nc1ccc(F)c(NC(=O)Nc2cccc(Cl)c2)c1 +CCOCC(=O)Nc1sc2c(c1C#N)CCCCC2 +c1ccc(C(CN2CCOCC2)Nc2ncnc3ccccc23)cc1 +CCNC(=O)c1ccc(C)nc1C1CCN(C(=O)C(C)C)CC1 +CS(=O)(=O)N1CCc2ccc(=O)n(CC3CC3)c2CC1 +CC(=O)NC1CCCN(C(=O)CNC(=O)C2CCCC2)C1 +COc1cc(C)ccc1NC(=O)NCC(=O)Nc1cccc(F)c1 +NC(=O)c1ccc(C(=O)N(Cc2ccco2)Cc2cccs2)cc1 +CCc1ccc(C2COCCN2Cc2cc(C#N)cs2)o1 +COc1ccnc(Nc2cnn(CC(O)CN3CCOCC3)c2)n1 +CN(C(=O)COC(=O)c1cccc(N)c1)C1CCCCC1 +CCC(C)Oc1cccc(NCC(C)C(N)=O)c1 +COc1cc(CC(=O)NCc2ccnc(OC3CCC3)c2)ccc1C +CC(=O)NC(C)C(=O)N(Cc1ccccc1)C(C)C +c1ccc(CCNc2c3c(nc4ncnn24)CCC3)cc1 +Cn1nc(C(=O)NC2(c3ccc(Cl)cc3)CCCC2)ccc1=O +O=C(COC(=O)C1CCOCC1)NCc1ccco1 +Cc1ccc2[nH]nc(C(=O)Nc3cccc(Oc4cnccn4)c3)c2c1 +COCCNC(=O)NCc1ccc(CN2CCCC2=O)cc1 +Cc1ccccc1CNC(=O)c1cnn(-c2ccccc2)n1 +Cc1nn(Cc2ccccc2)c(C)c1C(=O)N1CCc2ccccc2C1 +Cn1nc(C(=O)Nc2cccc(Cl)c2F)ccc1=O +COc1ccc(OC)c2c1CCNC2c1ccccc1 +CC(C)Nc1ncnc2c1CCN(C(=O)c1ncc(F)cc1F)CC2 +O=C(Nc1cc(F)c(F)c(F)c1)C1CCN(CC(F)(F)F)CC1 +O=C(Cc1ccc[nH]1)NC1(c2cccc(Br)c2)CCC1 +O=C(NCCCn1cccc1)c1cccc(Cl)c1 +Cn1cc(CCNS(=O)(=O)c2cccc(S(C)(=O)=O)c2)cn1 +COCCN1CCOCC12CCN(CCc1ccccc1)CC2 +CCC(Cc1ccc2c(c1)NCCO2)NCc1ccco1 +Cc1nonc1Cn1c(C)cc(=O)c2ccccc21 +CC(C)(CO)NC(=O)C1CCN(S(=O)(=O)c2ccccc2)CC1 +Cc1nc(-c2cc(C(=O)NC(C)c3ccccc3)n(C)c2)cs1 +CCCCN(CCO)C(=O)Nc1cc(F)ccc1C +O=C(NCc1ccn(C2CCCC2)n1)Nc1ccc2c(c1)COC2 +COC(=O)c1cc(NC(=O)C2CC2C)ccc1Cl +c1ccc(-c2cc(CSc3nnc(C4CC4)n3C3CC3)no2)cc1 +Nc1cc(F)ccc1C1NCCc2c(F)cc(F)c(F)c21 +Cc1cccc(N2C(=O)N(C)c3ccccc3S2(=O)=O)c1 +CC1=NC(=O)C(CCC(=O)Nc2cccc3cccnc23)C(C)=N1 +COC(=O)c1cc(COc2cc(C)c(C)nn2)c(C)s1 +O=C(NCCNC(=O)c1cc2cccnn2n1)c1ccc(F)cc1 +CC1CCCN(C(=O)Cn2nnc(-c3ccc(C(N)=O)cc3)n2)C1 +CC(C)n1cc(NC(=O)c2cc3c(=O)c4ccccc4oc3o2)cn1 +CCOC(=O)c1nn(CCc2ccccc2)c2ncccc12 +CC(=O)Nc1ccc(F)c(NC(=O)CCc2ccccc2)c1 +CCC(Nc1ccc(=O)n(CC)c1)c1cccs1 +O=C(c1nc(-c2ccc3cc[nH]c3c2)no1)N1CCCC1 +O=C(c1cn2ccsc2n1)N(CCO)Cc1nccs1 +O=C(Cn1ncc2c(N3CCCCCC3)ncnc21)NC1CC1 +Cc1csc(C2CC3CN(C(=O)c4cnoc4C)CCC3O2)n1 +O=C(CC(F)(F)F)Nc1ccc(-c2c[nH]cn2)cc1 +O=C(CCCc1nc2ccccc2c(=O)[nH]1)Nc1cccc(O)c1 +Cc1ccc(NC(=O)CCSc2nnc(-c3ccco3)o2)cc1 +NC(=O)C1CCCN1C(=O)Nc1cccc2cccnc12 +CCN(CCC(=O)OC)C(=O)c1ccccc1Br +C=CCNC(=O)NC1CCc2c(Cl)cccc21 +O=S(=O)(NCc1ccccc1)N1CCc2[nH]nc(C3CCC3)c2C1 +COc1ccccc1OC1CN(c2cc(C3CC3)ncn2)C1 +CC(Oc1ccccc1)C(=O)Nc1cc(Cl)ccc1N +CCN(CC)C(=O)CCC(O)c1ccccc1OC +C=CCCC(=O)Nc1ccc(OCC(=O)N(C)C)c(Cl)c1 +Cc1noc(NC(=O)c2csc(-c3cccs3)n2)n1 +CC(C)c1ccc(CN(C)C(=O)CNC(=O)c2ccsc2)cc1 +CC(C1CC1)N(C(=O)Nc1ccc2c(c1)OCCO2)C1CC1 +O=C(CCCc1ccccc1)Nc1cccn2c(C3CCC3)nnc12 +Cc1ccccc1OCCCC(=O)Nc1nncs1 +Cc1ccc(OCC(=O)NC(C)c2ccc3c(c2)OCO3)cc1 +CCOC(=O)COC(=O)c1cc(OC)ccc1Br +CC(=O)N1CCCCC1C(=O)Nc1ccc(-n2ccnc2C)c(F)c1 +CCCCC(=O)N1CCCC1C(=O)c1ccc(F)c(F)c1 +CCOC(=O)c1cnc2nc(C)nn2c1C=C(C)OCC +CSc1cccc2sc(NC(=O)c3c(C)cnn3C)nc12 +CCN(Cc1cccc(Cl)c1)C(=O)NCc1ccncc1 +Cc1ccncc1NC(=O)N(C)CCOc1ccccc1C +CC(C)c1ccc(S(=O)(=O)NCc2ccc(NC(N)=O)cc2)cc1 +Cc1cc(C(=O)NC(C#N)c2ccc(C(C)(C)C)cc2)no1 +Cc1ccc(C(=O)Nc2cccn3nc(C(C)C)nc23)cc1F +Cc1cc(C)n2nc(C(=O)NC(C3CC3)C3CC3)nc2n1 +CCc1cc(=O)[nH]c2nnc(SCC(=O)NC3CCCC3)n12 +CCCOc1ccc(OC(=O)C2CCN(C(=O)C3CC3)CC2)cc1 +COc1ccc(CNc2cccnc2)c2ccccc12 +Cc1cnn(C2CN(Cc3cccc(OCC(N)=O)c3)C2)c1 +CN(CC1CCCCO1)C(=O)c1ccc(-c2ccccc2)[nH]c1=O +N#Cc1cccc(C(=O)Nc2ccccc2N2CCCC2=O)c1 +CCN(CC)c1ccc(C(=O)Nc2ccccc2C#N)cn1 +CCC1CCc2ccccc2N1C(=O)c1ccc2nnc(C)n2c1 +Cc1oc(-c2ccsc2)nc1CC(=O)N1CCN(C(=O)CO)CC1 +Cc1nc(CNC(=O)NCCC2CCCCO2)sc1C +Cc1ccc(C2NC(=O)NC3=C2C(=O)N(CC2CCCO2)C3)cc1 +CCCc1nnc2sc(-c3ccc(OC)cc3)cc(=O)n12 +C=CCN1C(=O)C(C)Oc2c(OCC)cc(CO)cc21 +Cc1cccc(-c2nnc(SCC(=O)Nc3nnc(C)s3)o2)c1 +Cc1cc(Cl)ccc1OC(C)C(=O)NC(C)C1CCCO1 +N#Cc1ccc(C(=O)NCc2ccc(Br)cc2)cc1 +c1cnc(N2CCCn3nnc(COCC4CC4)c3C2)nc1 +CC(C#N)(NC(=O)CN1CCc2sccc2C1)C1CC1 +CCn1c(=O)c(C)nc2cc(C(=O)NCCC(C)C)ccc21 +COc1cccc(C2CCCN2C(=O)Cn2ccccc2=O)c1 +CCCC(C(=O)Nc1ccc(C#N)cc1)n1cc(Cl)ccc1=O +Cc1nc(Sc2ncccn2)c(C#N)c(C)c1Br +O=C1NCCc2ccc(NC(=O)C3(c4ccc(F)cc4)CC3)cc21 +CCC(=O)Nc1ccc(NC(=O)NCC(C)(C)C(N)=O)cc1 +CC(=O)NC(C#N)c1ccc(Br)cc1 +COc1ccc(OC(=O)C2CCOc3ccccc32)cc1F +COC(=O)c1cc(-c2cc(Cl)c(O)c(Cl)c2)nn1C +CC(C)=Cc1nnc(C(N)c2ccccc2C#N)o1 +COc1ccc(-c2nc(-c3ccccc3)c(C)n2O)cc1OC +CCc1cccc2c1OC(C)(C)C(CN1CCOCC1)C2N +CN(CCOCC1CC1)C(=O)c1ccc2ccc(Cl)cc2n1 +COc1ccc(C(=O)Nc2ccc3[nH]ncc3c2)nn1 +O=C(NC1CCCN(Cc2ccccc2)C1=O)C1CC1C1CC1 +O=C(NCC1CCOC1)c1ccc(C(F)(F)F)nc1 +CCOCC(=O)Oc1cccc(C(=O)N(C)C)c1 +COc1ccc(C(C)NC(=O)NCC(O)c2ccco2)c(OC)c1 +CC(=O)NC(C)C(=O)OCC(=O)c1c[nH]c2ccccc12 +O=C1CNc2ncnc(N3CCN(c4ccccc4)CC3)c2N1 +CS(=O)(=O)N1CCCN(C(=O)c2occc2-c2ccccc2)CC1 +CNC(=O)CN(c1ccc2c(c1)OCO2)S(C)(=O)=O +COc1ccc(-c2n[nH]cc2C(=O)NC2CCCCC2)cc1 +CCNC(=O)CNC(=O)NC1CCN(C(=O)C(CC)CC)CC1 +CC(C)OC(=O)c1cccc(-n2cc(CO)nn2)c1 +CCC(=O)Nc1ccc(S(=O)(=O)Nc2ccccc2OC)cc1 +CN(C)C(=O)CCNC(=O)NC1(Cc2ccccc2)CCCC1 +CC(=O)NCC1COCc2nc3cc(C(F)(F)F)ccc3n21 +Cn1ncc2c(=O)n(CC(O)COCc3ccccc3Cl)cnc21 +Cc1ccc2cnn(CCC(=O)NCc3cccc(F)c3)c2c1 +COc1cc2c(cc1CNC(=O)C1CC(=O)OC13CCCC3)CCC2 +Cc1ccc(C(=O)Nc2cccc3c2ccn3C)c(-n2cnnn2)c1C +COc1cccc(-c2nnc(NC(=O)c3nn(C)cc3C)o2)c1 +OCCN(Cc1ccc(F)cc1F)c1ccccc1 +Cc1ncc(CNC(=O)C2CC(=O)N(C)C2)s1 +CN(CC1CC1)C(=O)CNC(=O)Cc1cccc(F)c1 +Cc1ccc2cc(C)c3nnc(SCC(N)=O)n3c2c1C +CC(=O)N1CCC(NC(=O)NC2CCSc3ccccc32)CC1 +CC(C)C(=O)NCC(c1ccco1)N1CCc2ccccc21 +CC(c1nc(-c2ccccc2)n[nH]1)N1CCCC1=O +Cn1ncc2c(=O)n(CCC(=O)Nc3ccc(F)c(Cl)c3)cnc21 +CCNC(=O)CN1CCc2nc(NC(=O)c3ccccn3)sc2C1 +CCCn1nnc(NC(=O)c2ccc(OCC)cc2)n1 +NC(=O)c1cc(C2CCCN(C(=O)NCC3CCCO3)C2)n[nH]1 +c1cncc(CNCc2cccnc2OC2CCCC2)c1 +O=C(CN1C(=O)Cc2ccccc21)c1ccc(Cl)cc1 +CN(Cc1ccccn1)C(=O)Nc1ccc(N2CCCC2=O)cc1 +CC(=O)c1c[nH]c2ccc(Oc3ccccc3)cc2c1=O +COC(=O)COc1cccc(NC(=O)C2CCOC2)c1 +O=C(CNc1cc(F)ccc1F)Nc1ccc(F)cc1 +CCOc1ncccc1C(=O)NCCN(C)c1ccccc1 +Cc1ccnc(Sc2ccc(C#N)cc2Cl)n1 +CC(C)Cn1cc2c3c(cccc31)CN(C(=O)c1ccccn1)CC2 +Cc1ccc(S(=O)(=O)Oc2cccc(C#N)c2)cc1C +COc1ccc(-c2ncc(C(C)=O)s2)cc1F +COc1cc(C(C)O)ccc1OCc1ccccc1 +CCc1nc(C)c2c(n1)N(CCOc1ccccc1OC)C(=O)CC2 +COc1ccc(NC(=O)Oc2ccccc2)cc1OC +COC(=O)CC1CNC(N2CCCCC2)=NC1=O +CC(NC(N)=O)C(=O)NC1CC1c1cccc(Cl)c1 +COc1cccc(CNC(=O)CCc2c[nH]c3ccccc23)c1 +N#Cc1ccc(NC(=O)CCOCc2ccco2)cc1 +O=C(Cn1cccn1)Nc1ncc(Cc2cccc(Cl)c2)s1 +O=c1c2cnn(-c3ccccc3)c2ncn1CCCc1ccccc1 +CCOc1ccccc1-n1nnc(CO)c1-c1ccccc1F +O=C(NCC1CCCC1O)C1(c2cccc(F)c2)CCCC1 +CC(=O)NC(C)c1nc2ccccc2n1CC(=O)OC(C)C +Cc1nnnn1CC(=O)N(C)Cc1csc(-c2ccccc2)n1 +CCOc1ccc(C2(CNC(=O)NCC(C)C)CCOCC2)cc1 +CCCSc1c(CC)cnc2c1c(=O)n(C)c(=O)n2C +Cc1cccc(C)c1NCC(=O)Nc1ccc(Oc2cccnc2)nc1 +CCCn1cc(NC(=O)Cc2ccc(F)c(F)c2)cn1 +COc1cc(OC)cc(C(=O)NCc2sccc2C)c1 +CC(C)n1ncc2c(C(=O)OCC(=O)NC3CC3)cc(C3CC3)nc21 +Cc1ccc2c(c1F)CCNC2c1ccc(=O)[nH]c1 +Cn1c(=O)[nH]c(=O)c2c1nc(NCc1ccco1)n2CC(O)CO +Cc1cccc(-c2nnc(SCCC(N)=O)n2-c2ccccc2)c1 +Cc1ccc(NC(=O)c2cccc(C#N)c2)cc1S(=O)(=O)N(C)C +COc1ccc(CC(=O)NC2(C(N)=O)CCCCC2)cc1F +Cc1csc2ncn(C(C)Cn3cccn3)c(=O)c12 +CSc1ccc(N2CC(C(=O)Nc3nc(C)no3)CC2=O)cc1 +CCc1nc(CC(=O)Nc2cccc(Br)c2)cs1 +Cc1ccc(C(=O)Nc2ccc3c(c2)OCO3)c(N)n1 +O=C(Cn1c(=O)oc2ccccc21)NCCOc1cccnc1 +COc1ccc(F)cc1CN1C(=O)C(C)CS1(=O)=O +c1cncc(CNc2ccc(-c3nc4ncccc4o3)cc2)c1 +COCCNS(=O)(=O)c1ccc2c(c1)CCCN2C(C)=O +O=C(c1nc2ccccc2s1)C1CCN(C(=O)c2cc[nH]n2)CC1 +Cc1[nH]cc(Br)c(=O)c1OCc1ccccc1 +C=CCC(=O)N1CCOc2c(O)cc(-c3nc(C)cnc3C)cc2C1 +O=c1ccc(-c2csc(S(=O)(=O)N3CCCC3)c2)n[nH]1 +CCc1cc(NC2CCC(n3cnnc3)CC2)nc(N2CCCC2)n1 +Cc1ccc(OCCn2cnc3ccccc3c2=O)cc1 +O=C(OCC(=O)N1CCCC1)c1cc(F)ccc1Cl +CCNS(=O)(=O)CCNC(=O)c1ccc2c(c1)OCO2 +O=C(c1cccc2c1OCO2)N(Cc1ccco1)CC1CCCO1 +Cc1nn(C)c2nc(NCc3nc(C4CC4)no3)sc12 +CCCNc1ccc(S(=O)(=O)NCC(=O)NC)cc1 +CC(C)n1cc(-c2ccc(Cl)cc2)cc(C#N)c1=O +Cn1ccc(C(=O)NC(COc2ccccc2)c2ccccc2)cc1=O +O=c1c2ccccc2ncn1Cc1cccc(Cl)c1 +CCS(=O)(=O)NCc1ccnc(OC2CCCC2)c1 +CCN(Cc1ccccc1)C(=O)c1csc(NC(C)=O)n1 +CCCCc1nnc(NC(=O)CSc2ccc(F)c(F)c2)s1 +CC(C(=O)NC1CCCN(Cc2ccccc2)C1=O)C1CCOCC1 +Cc1nncn1CCNC(=O)c1ccc(-c2ccccc2)n1C +CC(NC(=O)Nc1nnc(C2CC2)s1)c1cccnc1 +Cc1ccc(F)c(C2NCCc3ccc4c(c32)OCCO4)c1 +Cn1cc(S(=O)(=O)Oc2ccc(NC(=O)C3CC3)cc2)cn1 +CCC(C(=O)Nc1cc(C)on1)N1CCOC(c2ccc(F)cc2)C1 +COc1ccccc1NC(=O)c1ccc(-c2ccccc2)[nH]c1=O +CCNC(=O)CSc1nnc(-c2ccco2)n1C1CCCCC1 +Cc1occc1C(=O)N1CCN(c2cnccn2)CC1 +N#Cc1c(OCC(N)=O)nc(-c2ccccc2)c2c1CCCC2 +CC(C(=O)Nc1ccc2c(c1)OCO2)N1CCN(C(=O)C2CC2)CC1 +Cc1cc(CN2CCN(C(=O)Cc3ccc4c(c3)CCO4)CC2)no1 +CC(O)(CNC(=O)c1c(F)cccc1Cl)C1CC1 +CCOCCC1(CNC(=O)Nc2ccn(C)n2)CCCC1 +CC(C)NC(=O)C1C2C=CC(CC2)C1C(=O)NC(C)C +COC(CNC(=O)CCC1CCCC1)c1ccc(C)s1 +CCS(=O)(=O)c1ccc(C(=O)N2CCN(CCO)CC2)cc1 +c1cnc(-n2cccn2)c(NCc2ccc(Oc3cnccn3)cc2)c1 +CCOC(=O)N1CCN(c2ccc3nc(N)nn3c2C)CC1 +CCCCn1ccc2[nH]c(=O)c(C(=O)OC)cc2c1=O +CC(=O)c1ccc(NC(=O)Nc2ccc3c(c2)OCO3)cc1 +CC(Nc1cc(Cl)ccc1F)c1ccncc1 +C=C(C)CN(C)C(=O)Nc1ccc(OCc2cccnc2)cc1 +CC(C)CN(CC(C)C)C(=O)c1n[nH]c2ccc(N)cc12 +Fc1ccc(N2CCN(Cc3nnnn3Cc3ccco3)CC2)cc1 +Cc1cc(NC(=O)CN2CCN(Cc3noc(C)n3)CC2)on1 +Cc1ccc(CN(C)C(=O)c2sc(C(C)C)nc2C)o1 +Cc1nn(C)c(C)c1CC(=O)Nc1nc(-c2ccc(F)cc2)cs1 +Cc1ccnc(-c2ccc(NC(=O)Cc3ccc[nH]3)cc2)n1 +Cc1occc1C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +CC(=O)NC(C)(C)c1noc(-c2cn(Cc3ccccc3)nn2)n1 +Cc1sc(=O)n(CC(=O)NC2CCCC(C)C2C)c1C +CC(O)CNC(=O)c1cccc(NC(=O)C(C)(C)C)c1 +O=C(NC1CCCCC1)c1nc[nH]c1C(=O)NCC1CC1 +O=c1[nH]c2cc3nc(-c4c(Cl)cncc4Cl)[nH]c3cc2[nH]1 +Nc1c[nH]nc1C(=O)NCc1ccc(F)cc1F +CCn1c(CN2CCN(CCO)CC2)nc2c(F)cccc21 +Cn1c(=O)n2n(c1=O)C1CC2C2C3CCC(CC3)C21 +COc1cc(C)ccc1NCC(=O)NCc1ccccc1F +Cc1cc(C(=O)NC(Cc2ccccc2)C(F)(F)F)no1 +CCn1c2ccccc2c2cc(NC(=O)CO)ccc21 +CC(=O)Nc1cccc(NCC(=O)N2CCCc3ccccc32)c1 +COc1ccc(NC(=O)C2CCCN(C(N)=O)C2)cc1Cl +COc1ccccc1Nc1ncnc2c1cnn2C +CC(C)C(NC(=O)Cc1ccccc1)C(=O)N(C)c1ccccc1 +CC1CN(CC2CCN(C(=O)Nc3ccccc3)CC2)CC(C)O1 +Cc1csc(NC(=O)CSc2nc(=O)c(C)c(O)[nH]2)n1 +CC(=O)Nc1sc2c(c1C(=O)Nc1ccccc1C)CCCC2 +O=C(CCCC(=O)N1CCC(CO)C(O)C1)c1ccccc1 +CN(CC1(C)COC1)C(=O)c1cc(Cn2cnc3ccccc32)[nH]n1 +Cc1ccc(CC(=O)N2CCOCC2CC(C)C)cn1 +CS(=O)(=O)NC1CCN(S(=O)(=O)c2cccs2)CC1 +Cc1ccc(C(N)c2ccc(S(C)(=O)=O)cc2)s1 +COc1ccccc1CC(=O)N1CCNC(=O)C1C +Cc1cc(C)c2oc(=O)c(C#N)c(N3CCCC3)c2c1 +Cc1cc(NC(=O)COC(=O)c2ccc3c(c2)CCC3)no1 +CN(Cc1ccc2c(c1)OCO2)C(=O)C1CCCO1 +COc1ccc(-c2nc(C3CCOC3)no2)cc1F +COC(=O)c1cccc(C(=O)Nc2cccc(F)c2)n1 +CCc1noc(C)c1C(=O)Nc1sc2c(c1C(N)=O)CCCCC2 +COC(=O)CCC1CCN(C(=O)CCC(C)C)CC1 +Cc1ccccc1OCC(=O)NC1c2ccccc2CC1O +CC(C)NC(=O)c1ccc(NC(=O)c2ccc3nccnc3c2)cc1 +Cc1cc(C)n(CCC(=O)N2CCCC2C(=O)Nc2ccccc2)n1 +Cc1nc(C)n(C2CCCN(C(=O)C(C)Oc3ccccc3)C2)n1 +CC1(C)COC(c2ccccc2)CN1Cc1ccc(C#N)o1 +CCS(=O)(=O)N1CCC(C(=O)N2CCCC2)CC1 +CCc1cccc(NC(=O)CNC(=O)NCc2ncn(C)n2)c1 +Cc1cn(CC(O)CN2CCOCC2)c(=O)n1-c1ccccc1 +CCOc1ccccc1Nc1ncnc(N2CCCCC2)c1N +O=C(NCCC(O)c1cccs1)c1cc(Cl)ccc1Cl +CNC(=O)NCC(=O)N(Cc1ccccc1)C(C)C +COc1ccc(OCc2nc(C(=O)N3CCN(C)CC3)cs2)cc1 +COCc1nc(C)c(C(=O)Nc2cccc(C(F)(F)F)n2)s1 +CCc1nnc(CNc2ccc(C(=O)OC(C)(C)C)c(C)c2)o1 +COc1cc(C)c(S(=O)(=O)N(C)Cc2csc(C)n2)cc1C +CCOC(=O)C1=C(c2ccccc2)NC(=O)C2OCCC12 +COc1cc2nc(-c3ccccc3C)n(CC#N)c2cc1OC +CCNC(=O)C1CCCN(C(=O)NCc2ccccc2CC)C1 +CC(=O)c1ccc(N2CCN(c3nccs3)CC2)c(F)c1 +Cc1cc(NC(=O)c2c(-c3c(F)cccc3Cl)noc2C)no1 +O=C(CSc1nnc(C2CC2)n1C1CC1)N1CCc2ccccc21 +CCCc1nnc(NC(=O)c2cnc(C3CCCO3)s2)s1 +Cc1cc(C(=O)Nc2ccncc2)ccc1S(N)(=O)=O +Nc1cc(CCc2nc(C3CC3)n[nH]2)ccc1Cl +O=C(NCCn1cncn1)C1CCCN1c1nc2ccccc2o1 +C=CCNC(=O)C1CCN(c2cc(F)cc(F)c2)C1=O +O=C(c1cccnc1)N1CCC(c2ccccc2)CC1 +CCOc1ccccc1NC(=O)Cc1c(CC)noc1CC +O=S(=O)(CCc1cccs1)c1ccc(F)cc1 +COCC1CN(C(=O)Nc2cc(Cl)ccc2F)CCO1 +COc1ccc(-c2nc(NC(C)C)nc3nn(C)c(N)c23)c(F)c1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccn(C(F)F)n1 +CC(=O)c1ccccc1NC(=O)CNc1cc(Cl)ccc1C(N)=O +O=C(c1ccccc1F)N1CCC(n2c(=O)oc3cccnc32)CC1 +COc1ncccc1C(=O)N1CC(c2ccccn2)C1 +NC(=O)CN(CCC1CCCCC1)C(=O)c1ccccn1 +Cn1c(CSc2ccccc2)cc(=O)n(C)c1=O +O=C(NCc1ccccc1)c1ccccc1NCc1nc(C2CC2)no1 +COC(=O)c1cccnc1N1Cc2cnn(CCO)c2C1 +COCCCNC(=O)Nc1ccc(-c2nc(C3CC3)n[nH]2)cc1 +COCCC(=O)NCc1c(C)nn(-c2ccccc2)c1C +CCCn1nnc2cc(-c3noc(-c4ccncc4)n3)ccc21 +Cc1ccc(-c2nc(NC(=O)c3cn(C)nc3C)sc2C)cc1C +O=C(c1cccc(NCc2cccc(F)c2)c1)N1CCC(O)CC1 +COc1cc(OC)cc(C(=O)N2CCC(C(=O)NC(C)(C)C)CC2)c1 +CCc1ccc(-c2nn(-c3ccccc3)cc2C(=O)NCCO)cc1 +CCCCNC(=O)Cn1cnc2c(Cl)cc(Cl)cc2c1=O +Cc1nc(C(=O)N(CCC(N)=O)c2ccc(F)cc2)cs1 +CCOc1ccc(C(=O)Nc2cccc(C)c2)cc1OC +CN1CCOCC12CCN(C(=O)c1cn(C)cn1)CC2 +NC(=O)C1CN(C(=O)COc2ccc(Cl)cc2Cl)CCO1 +CN(C)c1ccccc1C#CCNC(=O)COc1cccnc1 +CC1CCCN(S(=O)(=O)c2ccc3nnn(O)c3c2)C1 +CC(=O)N1CCC(NC(=O)c2cnn(-c3ccccc3F)c2C)CC1 +CCS(=O)(=O)Nc1c(C)nn(Cc2ccccc2Cl)c1C +O=C(c1cnccn1)N1CCC(Cc2ccccc2)CC1 +CCOc1ccc2c(c1)CN(C(=O)C1Cc3cc(F)ccc3O1)CC2 +CCC(C(=O)Nc1ccc(Cl)cc1)N1C(=O)CCn2nc(C)cc21 +CCCC(=O)NCC1CCCN(C(=O)Nc2ccc(OC)c(C)c2)C1 +O=C(c1cc2cc(F)ccc2s1)N1CCOC(c2ccccc2)C1 +Cc1ccc(NC(=O)c2cccc(N)c2)cc1Br +O=C(Nc1ccc(NC(=O)c2ccco2)cc1)Nc1cccnc1 +CCNC(=O)CC1CSc2nc(C)cc(=O)n21 +CCc1ccsc1C(=O)NCC(O)c1ccccc1 +CCC(O)c1ccc2c(c1)C(NC(C)=O)CC(C)(C)O2 +CCCn1ncc(-c2cc(C)ccc2C)c(C#N)c1=O +CC(=O)N(C)c1ccc(NCC(=O)NC2CCCCC2)cc1 +CC(C)n1cc(Cl)cc1C(=O)NC1CCC(O)CC1 +Cc1ccc(C)c(NC(=O)Cn2nc(-c3cccs3)oc2=O)c1 +O=C(Cc1ccc(F)cc1F)Oc1cccc(-n2cccn2)c1 +CCNC(=O)c1cccc(NCC(=O)Nc2ccc(F)cc2)c1 +COc1ccc(CNc2ncnc3c2cnn3-c2ccccn2)cc1 +CCOc1ccc(S(=O)(=O)Nc2ccccc2C(=O)OC)cc1 +CCNC(=O)CC(NC(=O)c1ccccc1)C(=O)OC +Cc1ccc(C(=O)OCC(=O)NCc2ccc3c(c2)OCO3)cc1 +N#Cc1cccc(NC(=O)c2cc(C3CC3)n3nccc3n2)c1 +CCCNC(=O)N(Cc1ccncc1)Cc1ccc(OC)cc1 +Cc1nc2ccccc2c(=O)n1-c1ccc(C(=O)N2CCCC2)cc1 +Cc1cc(C)n(-c2ccc(C(=O)NCCO)cc2)n1 +COc1ncc(Cl)c(N2CCCN(C(=O)c3ccccc3)CC2)n1 +COc1ccc(C(O)CNc2ccccc2C)cc1C +CCCC(=O)Nc1cccc(NC(=O)NCCN2CCOCC2)c1C +CC(NC(=O)Cc1ccc(Cl)c(Cl)c1)C1CCCO1 +CCc1ncc(C(=O)NCCc2ccccc2OC(F)(F)F)cn1 +COc1ccc(-c2nnn(-c3ccc(F)cc3)c2N)c(C)c1 +CCC(C)NC(=O)Cn1cnc2nc3c(cc2c1=O)CCCC3 +C=CCc1cc(C(=O)NC2CC3CCC2C3)ccc1OC +CCOc1ccc(C(=O)NCc2nc(C)no2)cc1 +COc1ccc(NC(=O)c2nc(C)oc2C)c(C)c1 +COc1ccccc1N(CCC#N)C(=O)CSc1nc(C)cs1 +Cc1cccnc1NC(=O)c1cccc(NC(=O)c2cccs2)c1 +O=C(Cc1ccccc1Cl)NCC(O)(c1ccco1)C1CC1 +CCOC(=O)c1cccc(NC(=O)c2cccc(OC)c2)c1 +COCC1(O)CCN(C(=O)c2cc(Cl)cc(OC)c2)CC1(C)C +CCC(C)NC(=O)CCNC(=O)c1ccc2[nH]cnc2c1 +Fc1ccc(CNC2COc3ccccc3C2)c(F)c1 +CC(NC(=O)Nc1ccncc1)c1cccc(Br)c1 +O=C1CCCc2c1c(C1CC1)nn2C1CCCCC1 +c1ccc(-n2ncc3c(NCC4CCCC4)ncnc32)nc1 +CCc1cc(C(=O)Nc2cccc(C(F)(F)F)c2)no1 +Cc1nc2sc(C(=O)NCc3ccco3)c(N)c2c(C)c1C +CCCNC(=O)C1c2ccccc2Oc2ccccc21 +COc1ccc(CN(C)C(=O)C(C)Sc2ccc(O)cc2)cc1F +CCN(CCC#N)C(=O)COc1cccc(F)c1C#N +c1ccc2c(c1)nnn2CCCCn1nnc2ccccc21 +CCCN(Cc1n[nH]c(=O)[nH]1)C1CC(OCC)C1(C)C +C#CCN1CCN(C(=O)NCCn2cccc2)CC1 +CC(C(=O)NC1CC1)N1C(=O)CCCc2ccccc21 +COC(=O)CC1CCCCN1C(=O)C1COCCO1 +COc1ccc(N)c(C(=O)NCCNS(C)(=O)=O)c1 +Cc1ccn2cc(C(=O)NCC(C)n3nc(C)cc3C)nc2c1 +CC(=O)N(C)CC(=O)Nc1ncc(Cc2ccccc2Cl)s1 +Nc1cc(N)cc(C(=O)Nc2ccc(N)cc2N)c1 +NC1=Nc2nc3ccccc3n2C(c2nc(-c3ccccc3)cs2)N1 +COc1cc(C)sc1C(=O)Nc1cc(F)cc(F)c1 +COc1cc(OC)cc(-c2nc3cc4c(cc3[nH]2)OCCO4)c1 +CCOC(C)c1noc(CNc2cccc(C(N)=O)c2C)n1 +N#Cc1cccc(C(=O)Nc2ccc(Cl)cn2)c1 +O=C(Nc1ccc(C(=O)NC2CC2)cc1)c1ccc2c(c1)OCCO2 +CC(NC(=O)OCc1ccccc1)C(=O)N1CCNCC1 +COCCNC(=O)c1cc2c(nc3sccn32)s1 +CC=Cc1nnc(C(N)c2cc(Cl)ccc2F)o1 +CC(CCCO)NC(=O)NC1CCCN(Cc2ccccc2)C1=O +Cc1ccc(N2CCC(C(=O)Nc3ccc(=O)n(C)c3)C2=O)cc1C +CCn1c(=O)c(C)nc2cc(C(=O)NC(C)C(C)C)ccc21 +O=C(COc1ccccc1Cl)Nc1ccc2c(c1)OCO2 +Cc1ccc2c(c1)NC1(CCCC1)C(=O)N2CCCC#N +CCC(CC)C(=O)c1cc2c(cc1F)NC(=O)CC2 +Clc1ccc(OCc2nc(C3CC3)no2)c(Br)c1 +COC(=O)CN(Cc1ccc(F)c(F)c1)Cc1cccc2c1OCO2 +CCOc1ccccc1NC(=O)c1cn(C)nc1C(F)(F)F +O=C1NCCCCC1n1cnc(-c2ccccc2)c1-c1ccc(O)cc1 +O=C(Cc1ccc2c(c1)CCC2)N1CCN(c2ccc(O)cc2)CC1 +C=CCNC(=O)c1nc(-c2ccoc2)n(-c2ccc(C)cc2)n1 +CN(CCOc1ccccc1)Cc1cnc(N2CCCCC2)nc1 +O=C(Cc1cccs1)NCCCN1CCOCC1 +O=C(Nc1ccc2c(c1)COC2=O)c1cccc(Cl)c1 +O=C(c1csnn1)N(Cc1ccco1)Cc1cccs1 +CCc1ocnc1C(=O)N1CCc2c(ncnc2N2CCOCC2)C1 +O=C(CSc1nnc2ccccn12)c1ccc2c(c1)OCCO2 +Cc1ccc(C(=O)NC2CCCC2)cc1-n1c(C)nc2cccnc21 +COc1cc(C#N)ccc1OCCn1nc(-c2ccco2)oc1=O +Cn1cc(CCNC(=O)NCC2COc3ccccc3C2)cn1 +O=C(c1cccs1)N1CCOC2C(OCc3cccnc3)CCC21 +COC(=O)C1CCCCN1Cc1cnn(C(C)(C)C)c1 +Cc1cccc(NC(=O)CCNC(=O)c2cnn[nH]2)n1 +N#CC(C(=O)CNC(=O)CC1CCCCC1)c1nc2ccccc2o1 +O=C(c1nnn(-c2cccc(F)c2)c1C(F)(F)F)N1CCC(O)C1 +O=C(CNc1ccccc1Cl)Nc1ccc(-n2cncn2)nc1 +COc1cc(OC)cc(OCCn2cc(N)cn2)c1 +Cc1cc(=O)c(C(=O)OCc2cccc(F)c2)nn1-c1ccccc1 +O=C(CN1CCN(C(=O)c2ccccc2)CC1)N1CCCC1 +O=C1C2CC(CN2Cc2ccc3nccnc3c2)N1c1ccccc1F +O=C(CSc1nnc2n1CCN2c1ccc(F)cc1)N1CCCC1 +CCOC(=O)CC(C)CNC(=O)c1ccc[nH]c1=O +COc1ccc(C2CC2C(=O)NCC(=O)NCc2ccccc2)cc1 +Cc1ccc(-c2csc(NC(=O)c3cnccn3)n2)s1 +Cc1cc(NC(=O)C2CCC(=O)N2)ccc1OC(C)C +Nc1n[nH]cc1S(=O)(=O)NCCC1CCCC1 +CN(Cc1cnn(Cc2ccccc2)c1)C(=O)c1nccnc1N +CCCCS(=O)(=O)NCC(=O)Nc1cc(C)n(C)n1 +O=C(Nc1cc(C(F)(F)F)ccc1Cl)N1CCOCC1 +Cc1cc(NC(=O)C(C)OC(=O)c2oc3ccccc3c2C)no1 +CC(=O)Nc1ccc(C#CCNC(=O)c2nc3ccccc3s2)cc1 +O=C(Cc1cccs1)N1CCCC1c1nc(-c2ccccc2)n[nH]1 +COCCOC1CCN(S(C)(=O)=O)C1Cc1ccncc1 +COCCC(=O)N(C)Cc1cc(-c2ccncc2)no1 +COC(=O)c1ccc(C)c(S(=O)(=O)Nc2ccncc2)c1 +Cc1ccc(-n2cnnc2SC(C)C(N)=O)c(C)c1 +COCC(C)NS(=O)(=O)c1ccc(OC)c(NC(C)=O)c1 +CCNC(=O)CNc1nc(C(F)(F)F)cs1 +CNC(=O)C(Cc1ccc(O)cc1)NC(=O)C1CC1 +CC1CC1CNC(=O)c1cc(-c2ccc(F)cc2)[nH]n1 +Cc1cccc(OCCC(=O)Nc2ccn(C)n2)c1C +CC(C)NC(=O)c1ccc(NCc2nsc(N(C)C)n2)cc1 +CC(C)(C)OC(=O)N1CCCC(c2ccccc2N)C1 +Cc1cc(NCc2ccc3c(c2)OCO3)n2ncnc2n1 +O=C(Cc1ccccc1)Nc1cc(N2CCOCC2)ncn1 +CCN(CC)C(=O)C(Sc1nc(C2CC2)n[nH]1)c1ccccc1 +CC1CN(C(C)(C)CNC(=O)c2cc[nH]n2)CC(C)O1 +CC(C(=O)Nc1cnc2[nH]nc(C)c2c1)=C1CCCC1 +CCCC(=O)NC(CO)C(O)c1ccc(N)cc1 +Cc1nn(CC(=O)Nc2ccc(F)cc2Cl)c(=O)c2ccccc12 +Cc1ncccc1NC(=O)Cc1ccc(F)cc1F +Cc1nnc(NCc2cnn(-c3ccccc3)c2)c(C#N)c1C +Cc1csc(C2CCN(C(C)c3nc(N)nc(N(C)C)n3)CC2)n1 +COc1ccc(N2CC(c3nc(C(C)(C)OC)no3)CC2=O)cc1 +O=C(CN1CCCCCC1=O)Nc1cccc(N2CCCC2=O)c1 +COc1ccccc1S(=O)(=O)C(C)C(=O)NCCC(C)C +CCn1cc(C#N)c(=O)n(CC(=O)NC(C)C(C)C)c1=O +COCCCNC(=O)c1ccc(N2CCSc3ncccc32)s1 +CCOC(=O)c1cc2c(C)n(C)c(C)c2cc(C(=O)OCC)c1=O +O=C(CN1C(=O)CCc2ccccc21)Nc1ccc(F)c(Cl)c1 +O=C(Nc1ccc(Br)cc1F)c1ccc(=O)[nH]c1 +O=C(NCC(O)CO)Nc1cccc(C#Cc2ccccc2)c1 +CC(C)C1(CNC(=O)CCc2nc3ccccc3c(=O)[nH]2)CC1 +COc1cccc(-c2ccnc3c(C(=O)NCC(C)C)cnn23)c1 +COCc1cc(CN(C)c2nc(C)nc3c2cnn3C)n[nH]1 +CC(C)c1cccc(OCCC(=O)N2CCC(O)CC2)c1 +CCc1cc(=O)[nH]c(C2CCCN2C(=O)COC)n1 +Cc1nc(CCNc2ccc(Cl)cc2)sc1C +O=C(Cn1nc(-c2cccs2)oc1=O)Nc1cc(F)cc(F)c1 +Cn1nc(C(=O)NC2CCN(c3nccs3)CC2)ccc1=O +CCOC(CC)C(=O)N1CCN(CC(=O)Nc2cc(C)on2)CC1 +O=C1CC(c2ccccc2)NC(Nc2nc3ccccc3o2)=N1 +CCCCSc1nc(N)cc(N2CC(N3CCOCC3)C2)n1 +CC(Sc1nncn1C)C(=O)N1CCOCC1 +CCOCC1CCCN(C(=O)CNC(=O)c2ccc3c(c2)CCC3)C1 +CC1CCCCC1NS(=O)(=O)c1ccc2c(c1)NCCO2 +CCOC(C)c1noc(CSc2nc(=O)ccn2C2CC2)n1 +Cc1nc(COc2ccccc2C(=O)N(C)c2ccccc2F)no1 +CS(=O)c1scc(-c2cccs2)c1C#N +CCC(C)CN(C)C(=O)Nc1ccn(CCOC)n1 +COc1c(F)cc(NC(=O)c2c[nH]nc2-c2ccccc2F)cc1F +Cc1n[nH]c(C2CN(CCOc3cccc(C#N)c3)CCO2)n1 +CC(=O)NCCNC(=O)c1nc(C(C)C)ncc1Cl +N#Cc1cccc(C(=O)Nc2cccc(Oc3ncccn3)c2)c1 +O=S(=O)(NCc1cccc(-c2nc[nH]n2)c1)c1ccccc1Cl +Fc1ccc(COc2ccc(Cn3ccnc3)cc2)cc1 +COc1ccc(C(=O)c2c(C)[nH]n(-c3ccccc3)c2=O)cc1OC +Cc1ccc2nc(C)c(C)c(C(=O)N(C)Cc3cnc(N)nc3)c2c1 +Nc1cccc(OS(=O)(=O)c2ccc(Cl)cc2)c1 +CC(NC(=O)c1c(O)cccc1Cl)C(=O)NC(C)(C)C +COCc1ccc(-c2nc(CC(=O)NC3CCCC3)no2)cc1 +Cc1ccc(-c2nc(CN3CCOC(C4CCCO4)C3)cs2)cc1 +CC1Sc2ccc(C(=O)N(C)C(C)c3cccs3)cc2NC1=O +COC(=O)C1CCCCC1NC(=O)c1cn[nH]c1C +Nc1cccc2c1nc(Cc1ccc(F)cc1)n2CCO +CC(=O)NCCNc1ncc(Br)c2c(F)cccc12 +CC(C)N1CCC(NC(=O)N2CCc3cc(F)ccc3C2)C1=O +Cc1ccnc(NC(=O)COc2ccc3c(c2)CCC3)n1 +CC(CO)NC(=O)CCc1cnn(-c2ccccc2)c1 +Cc1ccc(-c2csc(SCC(=O)N3CCCC3)n2)cc1 +Cc1ccc(C(=O)NCc2ccccc2Cn2cccn2)cc1 +CCn1c(-c2cccc(C(=O)NC3CC3)c2)nc2cccnc21 +Cc1ccc(CNC(=O)C(NC(=O)c2ccccc2)C(C)C)s1 +Cc1noc(C)c1CCC(=O)NC(c1ccc(F)cc1)C1CCCO1 +O=C(CCc1cc(F)ccc1F)NCC(=O)NC1CC1 +Cn1ncc(N2CCOC(CCNC(=O)CC3CCCC3)C2)cc1=O +CCCn1c(SCC2CCCO2)nnc1-c1ccncc1 +O=C(Nc1cccc(C(F)(F)F)c1)N1CCCCC1CCO +CCC(C)c1ccccc1N1CC(C(=O)Nc2cn[nH]c2)CC1=O +Cn1ncc2c1CCCC2NC(=O)CCn1ncc2ccccc21 +CCN(CC(=O)OC(C)c1nccs1)c1ccccc1 +CC(C)(C)c1cnc(COC(=O)c2ccn3cncc3c2)o1 +C=CCOC(=O)C(NC(=O)c1cccs1)C(C)C +COC(=O)C(NCC1CN2CCCCC2CO1)c1ccccc1F +COC(=O)CNc1cc(OC)c(Cl)cc1OC +Cc1ccc(CNS(=O)(=O)c2cccc(C#N)c2)c(C)c1 +O=C1CCC(COC(=O)c2cn(Cc3ccccc3)c3ccccc23)N1 +CC1CN(S(=O)(=O)Cc2cccc(F)c2)CC(c2ccccc2)O1 +CCC(C)C(NC(=O)c1ccc(F)cc1-n1cnnn1)C(=O)OC +CN(CCN1CCCCC1=O)c1nccc(C(F)(F)F)n1 +Cc1ccccc1CNC(=O)NCc1cccc(NC(=O)C2CC2)c1 +Cc1cccc(NC(=O)CCSc2nnc(-c3ccco3)o2)c1 +CS(=O)(=O)c1ccc(-c2ccc3[nH]ncc3c2)cc1 +CCOC(=O)CN(C)C(=O)CN1CCCCCC1=O +CN(C)c1cccc(C(=O)Nc2cccc(-n3cnnn3)c2)c1 +COC(=O)N1CCC(NC(=O)c2sccc2C)CC1 +COc1ccc2c(c1)CC(NC(=O)NCCc1ccccc1)CO2 +Cc1cnc(NCc2c(C)nn(C)c2Oc2cccnc2)s1 +CC1C(=O)N(c2cccc(C(F)(F)F)c2)CCN1C(=O)C1CC1 +Cc1csc(C2CN(Cc3cc(C#N)cs3)CCO2)n1 +Nc1c(-c2cccnc2)nsc1C(=O)Nc1ccccc1 +Cc1nc(C)c(C(=O)NCCNc2cc(-n3cccn3)ncn2)s1 +Cc1ccc(CNC(=O)c2ccc(S(=O)(=O)NC(C)C)cc2)cc1 +COc1ccc(S(=O)(=O)NCc2cc3ccccc3[nH]2)cc1 +CCn1cc(C(=O)NC(C)C(=O)Nc2ccc(C)cc2F)c(C)n1 +Cc1nc(COc2ccccc2C(=O)OC(C)c2ccccn2)no1 +C#CCN1CCN(C(=O)NCc2ccc(OC)cc2OC)CC1 +Cc1oc(-c2ccccc2)nc1-c1c(-c2ccccc2)ncn1CCO +O=C(Cc1ccsc1)N1CCC(n2c(=O)[nH]c3cncnc32)C1 +CC(Cc1cnccn1)NC(=O)Cn1ccnc1-c1ccccc1 +COc1ccc(C(=O)NCC(C)(C)c2ccccc2Cl)nn1 +O=C(Nc1c[nH]ccc1=O)c1ccc(S(=O)(=O)C2CCCC2)cc1 +COc1ccc(N)cc1-n1cc(-c2cccs2)nn1 +COc1cc2c(cc1OC)C(c1ccccc1OC(C)C)CC(=O)N2 +CSc1nnc(C)c(=O)n1COC(=O)c1cccc(F)c1 +CS(=O)(=O)n1nc(OC(=O)c2ccc(Cl)cc2)cc1N +Cc1ccc(CCc2nnc3c(C)cc(N)cn23)cc1 +COC(=O)C(C)NC(=O)NCc1ccc(Cl)cc1 +CC(C)N(C)c1ccc(NC(=O)CNC(=O)C2CCCC2)cc1F +CN(CCC#N)C(=O)c1ccccc1C(F)(F)F +Cc1nc2ccccc2n1CCc1noc(-c2cccs2)n1 +COC(=O)CNC(=O)CC1Oc2ccccc2NC1=O +Cc1cc(NC(=O)COc2ccc(Br)cc2)no1 +CC(=O)N1CCc2cc(NC(=O)NCCc3ccccn3)ccc21 +COCCC(=O)N(Cc1ccc2c(c1)OCO2)C1CCCCC1 +Cc1nc2cc3c(cc2n1CC(C)C#N)OCCO3 +CCN(CC)C(=O)c1ccc(NCc2nc(C3CC3)no2)cc1Cl +C=CCOc1cccc(NC(=O)N2CCCC2c2ccncc2)c1 +CC1=CC(C)=NC(=O)C1CNC(=O)Cn1cnc2c(cnn2C)c1=O +CC1CN(CC(=O)Nc2nncs2)CC(C)O1 +COc1ccc(CCSc2nnc(Cn3cncn3)o2)cc1 +COc1ccc(Nc2ncccc2S(N)(=O)=O)cc1Cl +NC(=O)C1CCCN(C(=O)CSc2ccccc2Cl)C1 +O=C(c1cccc(-n2cccn2)c1)N1CCCC1c1nccs1 +CC(NC(=O)c1ccccc1Cl)C(O)c1ccccc1 +Cn1c(-c2ccc(C(N)=O)s2)nc2ccccc21 +CC(=O)c1ccc(N2CCN(C(=O)c3ccc4nccn4c3)CC2)cc1 +COc1ccc(C(=O)NCCc2cn3ccccc3n2)cc1 +Nc1c(NCCC2=CCCCC2)ncnc1N1CCCC1 +Cc1n[nH]c(C)c1CCC(=O)NC1CCCC(C(F)(F)F)C1 +CC(C)CCCNC(=O)c1ccc(-n2cncn2)cc1 +NC(=O)c1ccc(=O)n(CCCc2cccc(F)c2)n1 +CN(Cc1nccn1Cc1ccccc1)C(=O)c1cccc2ccnn12 +CCc1nnc(CS(=O)(=O)c2ccc(C)c(C)c2)n1C +CCOC(=O)c1c(C2CC2)csc1NC(=O)c1ccccc1C +c1ccc(C2(c3nn(-c4ncccn4)c4c3CNCC4)CC2)cc1 +CC1Sc2ccc(C(=O)N3CCc4ccccc4C3)cc2NC1=O +Clc1ccc(-n2ncnc2-c2ccc3c(c2)OCO3)cc1 +CCC(C)(CO)NC(=O)Nc1ccc(C)cc1Cl +N#Cc1ccc(S(=O)(=O)NCCc2ccccn2)cc1Cl +CCOc1cc(CNC(=O)c2ccc(CC)o2)ccc1OC +Nc1ccn(-c2cc(C(F)(F)F)ccc2Cl)n1 +O=C(OCCNc1cccnn1)c1scnc1C1CC1 +CN(CCC#N)C(=O)c1cc(-c2ccccc2)nc2cc(F)ccc12 +N#Cc1nccnc1NC12CC3CC(CC(C3)C1)C2 +Cc1nc(-c2ccccc2)c(C(=O)N(C)Cc2snnc2C)s1 +CC(C)CN(C(=O)Cn1cnc(C2CCC2)cc1=O)C1CC1 +CC(=O)N1CCN(C(C)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)CC1 +O=C(NCCn1cnc(-c2ccccc2)cc1=O)c1ccccn1 +CC1COCC(C)N1CCCn1c(=O)c2c(ncn2C)n(C)c1=O +O=C(Cc1cccs1)N1CC(c2nc(-c3ccccn3)no2)C1 +O=C(Cn1ccc2ccc(F)cc21)Nc1cccc2ncccc12 +Cc1ccc(S(=O)(=O)Nc2ccsc2C(N)=O)c(F)c1 +CNS(=O)(=O)c1ccc(OC)c(NC(=O)c2ccccc2C)c1 +Cc1ccc2nc(C)c(C)c(C(=O)N3CC4CCCC4(CO)C3)c2c1 +COc1cc(F)c(C(C)NC(=O)COC2CCCCC2)cc1OC +COC(=O)c1ccc(NCc2nsc(N(C)C)n2)cc1Cl +COc1ccc(OCC(=O)N(C)Cc2ccc(OC)c(F)c2)cc1 +CC1CC(Sc2nnc(-c3ccccc3Cl)n2N)C(=O)O1 +O=S(=O)(c1ccc(F)cc1)N1CCc2nc[nH]c2C1 +O=C(NC1CCc2c(ccc(=O)n2Cc2ccncc2)C1)c1ccc[nH]1 +CCOc1cc(C)c(C(=O)CCC(=O)OC)c(C)c1C +O=C(CNC(=O)NCc1cccnc1OC1CCCC1)NC1CC1 +CCCNC(=O)C1CCCN(C(=O)c2ccc(-n3ccnn3)cc2)C1 +CNC(=O)c1cc(NCC2CCOC2)ccc1Cl +CCOc1ccc2nc(SCC(=O)OC(C)C)[nH]c2c1 +Cc1c(C(C)NC(=O)c2cc3c(ccc4ccccc43)[nH]2)cnn1C +Cc1cc(C(=O)Nc2cccnc2N2CCOCC2)c(C)n1C1CC1 +CN(C1CCCCC1)S(=O)(=O)NCC(=O)Nc1ccc(F)cc1 +Cn1cnc2cc(-c3noc(-c4ccc5c(c4)OCO5)n3)ccc21 +COc1ccc(Nc2cc(-c3ccccn3)nc(C)n2)cc1 +Cc1cc(CN(C)C(=O)CSc2ccccc2C)no1 +Cc1nc(-c2ncccn2)sc1C(=O)N(C)CC1CCCC1 +O=C(c1cc[nH]n1)N1CC2CN(c3ncccn3)CCOC2C1 +Cc1csc(N2CCN(C(=O)c3ccc(N(C)C)nc3)CC2)n1 +O=c1ccn(Cc2nnc(-c3ccccc3)o2)c2ccsc12 +CC1(NS(=O)(=O)c2ccc3c(c2)OCCO3)CCCC1 +CCn1nnc(NC(=O)c2ccc3c(c2)OCCO3)n1 +O=C(NCCCNC(=O)c1ccnc2c1OCO2)c1cccs1 +Cc1ccccc1Oc1ncccc1CNC(=O)c1ccnn1C +COc1ccc2cc(C(=O)c3ccc(NS(C)(=O)=O)cc3)oc2c1 +CN(C)S(=O)(=O)Nc1ccc(S(N)(=O)=O)cc1 +CCC(=O)Nc1nc(-c2ccc(Cl)cc2)nc(C)c1C(C)=O +CCCNC(=O)CNC(=O)c1cc(N)ccc1F +Cc1ccc(C(=O)N(C)CCOCC2CC2)cc1Cl +CCOCCCC(=O)NC(C#N)c1ccc(Cl)c(Cl)c1 +Cc1cc(C(=O)N2CCC(C(N)=O)CC2)c(C)o1 +O=C(NCc1ccnc(-n2cccn2)c1)N1CCc2ccccc21 +COC(=O)C(CC(C)C)NC(=O)Nc1ccc(F)cc1 +CC(=O)N1CCCC1C(=O)Nc1ccccc1OC(F)F +COCc1cc(NCc2c[nH]c(=O)[nH]c2=O)ncn1 +COCCNC(=O)c1cccc(Oc2nccc(C)n2)c1 +CCc1nnc(CNC(c2ccccc2)c2cccc(Cl)c2)o1 +C#CCNC(=O)C(C)Nc1ccn(CC(F)(F)F)n1 +Cc1occc1C(=O)N1CCN(Cc2ccc(Cl)cc2)CC1 +Cc1ccc(C)c(S(=O)(=O)NCc2cccc3cccnc23)c1 +CCOc1cc(C#N)ccc1OCC(=O)Nc1ccc(C)cc1O +CC(=O)c1ccc(NC(=O)c2cc(F)c(F)cc2F)cc1C +CCc1onc(C)c1NC(=O)N(Cc1cccc(F)c1)C1CC1 +CC(C)COC(=O)CN1C(=O)C(C)(C)Oc2cccc(N)c21 +Cc1ccc(NC(=O)c2cnn(Cc3ccccc3Cl)c2)nc1 +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2c(C)noc2CC)c1C +CN(Cc1ccccn1)C(=O)C1Cc2cc(F)ccc2O1 +CCc1ccc(C(=O)NCc2cccc(OC(C#N)CC)c2)o1 +COc1cccc2c1SCC(C(=O)N1Cc3cncnc3C1)C2 +Cc1cc(C)c(NC(=O)c2cccc(N(C)C)c2)c(C)c1 +CC(C)(CNC(=O)CCC(=O)c1ccc(F)c(F)c1)c1ccncc1 +CC(C)(C)c1nnnn1CC(=O)Nc1cccc2ccccc12 +CCn1c(=NC(=O)c2ccc(NC3CC3)nc2)[nH]c2ccccc21 +O=C(Nc1nnc(C2CC2)s1)c1cccc(Oc2ccccc2)c1 +CCOc1ccc(C(=O)NC2CCCNC2=O)cn1 +CCC(C)c1ccccc1OCC(=O)Nc1c[nH]c(=O)[nH]c1=O +Cc1ccc2c(c1)c1nnc(SCC(N)=O)nc1n2C +Cc1csc(C2CN(CC3=CCCOC3)CCO2)n1 +CCSc1ccc(Cl)cc1C(=O)NC(COC)C(N)=O +COc1cc(CNc2nnc(C)c(C)c2C#N)ccc1O +CN(C)C(=O)C1CCCN1C(=O)C1CC=CCC1 +CCOCCN(CC)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +COc1ccccc1-c1nc2cc(C)cnc2n1CCCO +CCC(CO)n1c(C)cc(=O)c(O)c1CN(C)CCO +CCC(C)(C)NS(=O)(=O)c1ccc(N2CCOC2=O)cc1 +COc1ccccc1OCC(=O)N(C)Cc1ccc(F)cc1 +N#CC(CC(=O)N1CCCCCC1)C(=O)N1CCCC1 +Cn1cc(C(=O)N(Cc2ccc(F)cc2)C2CC2)ccc1=O +Cc1noc(C)c1CS(=O)(=O)c1nc(C)c(C)n1C1CC1 +Cc1csc(C(C#N)C(=O)CNC(=O)CC(C)(C)C)n1 +CCSc1ccc(-n2cnc3ccccc3c2=O)cc1 +COCCN(Cc1ccsc1)S(=O)(=O)c1c(C)nn(C)c1C +Cn1cc(Nc2ccccc2S(N)(=O)=O)cn1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)CCCn1cncn1 +CNC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1 +O=C(Cc1ccc(F)cc1)Nc1ccc(Cl)cn1 +c1cnc(N2CCCN(c3ncnc4ccsc34)CC2)nc1 +COC(=O)c1cc(N)n(-c2ccc(C(C)(C)C)cc2)n1 +COc1cc(OC)c2c(C)c(CC(=O)N3CCOCC3)c(=O)oc2c1 +CN(C)c1ccc(C(=O)NCCc2cccc(Cl)c2)cn1 +CSc1nc(C(=O)Nc2c(C)cccc2C)c2ccccn12 +CCc1cccc(OCc2nnc3cc(C)c(N)cn23)c1 +Cc1c(C(=O)NCC(C)C)c(=O)oc2ccc(Br)cc12 +CCc1cccc(NC(=O)COc2ccccc2O)c1 +CCCc1ccc(NC(=O)N2CCC(CN3CCOCC3)C2)cc1 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+Nc1c(Cl)cccc1C(=O)NCc1ccncc1 +CC(=O)c1c2c(nc3ccc(C)cc13)CCN(C)C2 +Cc1csc(CNCCc2ccc(F)cc2)n1 +O=C(Nc1ccccc1Cl)c1cc(F)cc2[nH]cnc12 +COCc1nc2ncc3c(=O)n(-c4cccc(C)c4)ccc3n2n1 +CCNS(=O)(=O)c1ccc(CC(=O)Nc2ccccc2C)cc1 +COC(=O)C(NC(=O)c1ccn(-c2ccccc2Cl)n1)C(C)C +C=CCSc1nnc(COc2ccc(F)cc2)o1 +CCCOc1ccc(NC(=O)N(C)CCC#N)cc1Cl +COc1ccc(CN(CC(=O)N(C)C)CC(F)(F)F)cc1O +CCNC(=O)CNC(=O)CN(C)C(=O)c1cccs1 +CCC(C)NC(=O)C12CCC(C)(C(=O)C1)C2(C)C +Cc1ccc(-c2cc(CSc3ncnc4c3cnn4C)on2)cc1 +O=C(NCC(=O)N1Cc2ccccc2C(c2ccccc2)C1)C1CC1 +COc1ccc(CN2CCC(c3cc(=O)[nH]c(C)n3)C2)cc1OC +O=c1c2nccnc2ncn1CC1COc2ccccc2O1 +CCN(C(=O)NCCCn1nc2n(c1=O)CCCC2)C(C)C +Cc1cc(O)cc(C)c1NC(=O)C1CCCCN1C(=O)OC(C)(C)C +CC(=O)NC(C(=O)N(Cc1ccc(Cl)cc1)C1CC1)C(C)C +O=C(Nc1c(-c2ccc(F)cc2)nc2sccn12)c1ccco1 +Cc1cc(OCCCC(=O)N(C)CC(=O)N(C)C)ccc1Cl +CCCOc1ccc(-c2cc(C(=O)NCC)nc(N)n2)cc1 +CCc1nnsc1C(=O)NC(C)Cn1cccn1 +CCc1cccc(C)c1NC(=O)CC(C#N)c1ccccn1 +CCC(C)(C)C1CCC(NC(=O)c2nccnc2N)CC1 +COc1cc(C(=O)NCc2cccnc2)cc(OC)c1C 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+O=C(CSc1ccccn1)NC1CCOCC1 +CCNC(=O)c1ccc(NC(=O)Cc2cn3ccsc3n2)c(C)c1 +N#Cc1ccc(Oc2cccc(NC(=O)CC3C=CCC3)c2)nc1 +CC(C)OCCNC(=O)c1ccnn1-c1ccc2ccccn12 +Cc1nc(Nc2ccccc2)cc(-c2ccccn2)n1 +COc1ccc(NC(=O)C2CC=CC2)cc1OC1CCCC1 +Cc1oc(-c2cccc(C(F)(F)F)c2)nc1CN1CCNC(=O)C1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NC(C)CO +CCCCCC(C)NC(=O)c1cnc2[nH]nc(C)c2c1 +Cc1cccc(C(=O)NCCN2CCOCC2)c1C +Cc1cnc(NCc2cnc(C3CC3)s2)s1 +Cn1ccnc(NC(=O)C2CC(=O)N(C3CCCCCC3)C2)c1=O +CN(C)C(=O)CC(NC(=O)Nc1ccc(C#N)cc1)c1ccccc1 +Cc1cc(C)n(-c2ccc(NC(=O)N(C)C(C)CC#N)cn2)n1 +Cn1nnnc1SCC(=O)Nc1ccccc1Br +O=C(Nc1ccc(Cl)c(Cl)c1)N1Cc2cncnc2C1 +O=C(NC1CCCCC1)C1CCCN1C(=O)NCc1ccccc1 +CSc1cccc(NC(=O)c2oc3ccc(F)cc3c2C)c1 +Cc1c(C(=O)N(Cc2ccccc2)CC(O)c2ccco2)cnn1C +CCC(C)N(C)C(=O)Nc1ccc(OC)c(NC(C)=O)c1 +COc1ccc(C(=O)NCCn2ncccc2=O)c(OC)c1 +C=CC(C)NC(=O)C1CCCC1C(=O)NC(C)C=C +C#CCN(C)CCC1CCC(O)C(C(=O)N2CCOCC2)O1 +CSc1ccc(C2CC(O)=Nc3c2cnn3C2CCCC2)cc1 +NC(=O)CC1CCN(C(=O)Cn2c(=O)cnc3ccccc32)CC1 +CC(N)C(=O)OCc1ccc(SC2CCCC2)cc1 +Cc1nc(N(C)Cc2cc(-c3cccnc3)no2)c2ccsc2n1 +COc1ccc(C(=O)NCCCn2ccc3ccccc32)cc1OC +COc1cccc2cc(C(=O)NCC3CCCO3)c(=O)oc12 +Fc1cc(F)c(NCc2ccccn2)c(Br)c1 +CC(C)C(=O)N(Cc1cccs1)Cc1cccn1C +C=CCNC(=O)c1ccccc1NC(=O)CCC1CCCC1 +CCCCNC(=O)C(C)N1CCN(C(=O)c2cccc(F)c2)CC1 +COc1cccc(-c2c[nH]cc2C(=O)N2CCCC(NC(C)=O)C2)c1 +CCCn1c(SCc2cccnc2)n[nH]c1=O +CC1(C(=O)N2CCOCC2)Oc2ccccc2NC1=O +CC(=O)NCCNC(=O)C(C)(C)c1ccc(Cl)c(Cl)c1 +Cc1ccc2[nH]nc(C(=O)NCc3nc(C)sc3C)c2c1 +CCC(C(=O)NCc1ncn(C)n1)c1ccccc1 +CCc1ncc(CN(C)C(=O)c2cnc3sc(C)cn3c2=O)s1 +O=C(c1ccco1)N1CCN(c2cnnc(N3CCCC3)c2)CC1 +O=C(Nc1ccc(Cl)cn1)c1cnn2cccnc12 +CN1C(=O)COc2ccc(C(=O)N3CCC(C(N)=O)CC3)cc21 +Cc1cc(NC(=O)c2cc(C)n(C3CC3)c2C)ccc1C(=O)N(C)C +Cc1cccc(NC(=O)c2sc3nc(N)c(C#N)cc3c2N)c1C +O=C(Nc1ncn(Cc2ccccc2)n1)c1ccc(Cl)cc1 +CC1CN(C(=O)Nc2cccc(OC(F)F)c2)CCO1 +CC(O)c1nc2ccccc2n1Cc1ccccc1Cl +COc1ccc(C(C)NC(=O)Cc2csc(C(C)C)n2)cc1F +CC(C)CCNC(=O)c1cccc(Oc2cnccn2)c1 +CCn1nc(C)c(C(=O)Nc2nc(C)cs2)c1C +CCOC(=O)c1cnc(NCc2ccccc2)s1 +CC(C)C(NC(=O)c1n[nH]c(N)n1)c1ccccc1 +CCCOCCNC(=O)c1csc(C(C)=O)c1 +CCn1cc(C(=O)N2CCC(NS(C)(=O)=O)CC2)cn1 +CCOC(=O)CN(C(C)C)S(=O)(=O)N1CC(C)CC(C)C1 +CCC(C)(C)c1ccc(OC(=O)C2CCCN(C(N)=O)C2)cc1 +Cc1ccc(-c2nc3cc(CO)ccn3c2C)cc1C +N#CCCN(C(=O)c1ccc(Cl)c(N)c1)c1ccccc1 +CCC(C)NC(=O)CCNC(=O)N1CCC(C)(C)C1 +COc1ccc2[nH]cc(CC(=O)N(C)CCC(F)(F)F)c2c1 +CN(C)C(=O)COC(=O)c1ccc(-n2cccn2)c(F)c1 +COC(=O)c1cccc(Cn2ccnc2CCN2CCOCC2)c1 +C=C(C)CN(CC)C(=O)Nc1ccc(CN(C(C)=O)C2CC2)cc1 +CCNC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1OC +O=C(NCc1cnn(-c2ccccc2)c1)C1Cc2cc(F)ccc2O1 +Cc1cc(C)cc(-c2nnc(SCC(=O)N3CCNC(=O)C3)o2)c1 +COc1ccc(Cl)cc1CCNC(=O)NC(C)c1ccccn1 +COC(=O)c1cccc(CSc2nnc(C(F)(F)F)n2C)c1 +COC(=O)CN(C(=O)Cc1ccc(OC)cc1)C(C)C +COc1cccc(NC(=O)NC2CCN(c3ccc(F)cc3)C2=O)c1 +Cn1cc(-c2cc(-c3ccc(Cl)cc3Cl)nc(N)c2C#N)cn1 +Cc1cc(C)nc(Cn2ccnc2-c2cccc(Cl)c2)n1 +Cc1c(C)n(Cc2ccccn2)c2ncnc(NCc3ccccn3)c12 +O=C(CNC1=NS(=O)(=O)c2ccccc21)Nc1cn[nH]c1 +CN(Cc1nnc2n1CCC2)C(=O)CC1C=CCC1 +CC1CCCC(NC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)C1 +c1ccc(SCc2nc(-c3ccco3)no2)cc1 +Cc1ccc(CN(C(=O)c2ccccc2)c2ccccn2)o1 +Cn1c(C(=O)N2CCCC3(CCOC3)C2)ccc1-c1ccccc1 +CCN(Cc1ccccc1Cl)C(=O)C1CCCO1 +CCS(=O)(=O)N(C)C1CCN(C(=O)NCC(F)(F)F)CC1 +C#Cc1cccc(NC(=O)NCCNC(=O)c2ccc(O)cc2)c1 +CC(=O)NCC1CN(C(=O)C(C)CCc2ccccc2F)CCO1 +Cc1ccc(SCCN2C(=O)c3ccccc3S2(=O)=O)nc1 +CCCCn1ncc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c1C +O=C1OC(C(=O)Nc2ccccc2F)Cc2ccc(Cl)cc21 +COC(=O)c1cc(Cl)ccc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C +CCOc1ccc(N2CC(CNC(=O)C3CCCC3)CC2=O)cc1 +O=C1CCC(C(=O)N2CCN(Cc3ccccc3)CC2)N1 +COc1ccc(C(=O)COc2cccc(N)c2)c(OC)c1OC +CC1CC=CCC1COC(=O)c1cccc(=O)n1C +O=C(NCc1ccc(Cn2cccn2)cc1)c1ccccc1F +COc1cccc(NC(=O)NCCc2nc3ccc(F)cc3[nH]2)c1 +CSc1ncc(-c2c(C)c(-c3ccc(O)cc3)nc(N)c2C#N)cn1 +CC1CCC(NC(=O)NC2CCC(O)CC2)CC1 +CNC(=O)C1CCC(NC(=O)c2cc(C)no2)CC1 +COc1ccc(CN(C)Cc2nc3c(cnn3C)c(=O)[nH]2)cc1 +Cc1cc(C(=O)N2CCCC2C(N)=O)c2cc(F)ccc2n1 +COc1cc(NC(=O)Cc2ccc(Br)cc2)ncn1 +Cc1oc(-c2ccccc2)nc1C(=O)OCC(=O)N1CCC(C)CC1 +O=C(CCc1ccco1)c1ccc(C2OCCCO2)cc1 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+CCCC(=O)Nc1cccc(NS(N)(=O)=O)c1 +NC(=O)C1CCN(C(=O)C2(c3ccc(F)cc3)CC2)C1 +Clc1ccc(Cc2nn(-c3ncccn3)c3c2CNCC3)cc1 +O=C(NCCOc1ccccc1Cl)c1ccn2cncc2c1 +Cc1ccccc1CN1CCCN(c2ccc(C(N)=O)cc2)C1=O +Cc1ccc(S(=O)(=O)NC(C)CN2CCCC2=O)c(F)c1 +CCCOc1cc(C(=O)NCCC(C)C)ccc1N +CCCC(C)NC(=O)N1Cc2c(OC)ccc(OC)c2C(O)C1 +COc1c(Cl)c2c(c(OC)c1OC)CNCC2(C)C +COc1ccc(C(=O)OC2CCCC2OC)cc1 +CSc1nnc(NS(=O)(=O)c2ccc(F)cc2)s1 +Cc1cc(C)cc(N2CCN(C(=O)c3occc3C)CC2=O)c1 +CCOc1ccc(C2=CCN(C(=O)c3nccnc3N)CC2)cc1 +COC(=O)CNC(=O)c1ccc(-c2ccc(C)cc2)o1 +Cc1nnc(SCC(=O)Nc2ccccc2C(=O)NC2CC2)s1 +CCOC(=O)N(C)c1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +N#Cc1ccccc1NC(=O)C1CCN(c2ccccc2F)CC1 +O=C(CCc1cccs1)NCCCC(=O)N1CCc2ccccc21 +CN(c1cccc(Cl)c1)S(=O)(=O)c1cccc(C(N)=O)c1 +O=C(CSc1nnc(C2CC2)o1)c1ccc2c(c1)CCC2 +O=C(Nc1ccc(O)cc1F)c1cc(Cl)ccn1 +COCCNC(=O)c1ccc(Cl)c(NC(=O)C2CC2C)c1 +COc1ccnc(N2CCN(CCOCC(F)(F)F)CC2)n1 +Cc1cc(C(=O)N2CCNC(=O)C2)c(C)n1Cc1cccs1 +Nc1ccccc1OCC(=O)NCC1CCCCO1 +CNC(=O)CCOc1ccc(NC(=O)C2CC=CC2)cc1 +Cc1ccc(Cl)cc1-n1nc(C)c2c1CCNC2 +Cc1cc(N)ccc1NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +CSc1nn(-c2ccc(C)c(Cl)c2)c(N)c1C#N +C#CCN1CCN(C(=O)c2c(F)ccc(OCC)c2F)CC1 +O=C(NCc1cccs1)c1cc(N2CCCC2=O)ccc1Cl +O=C(CCc1nc(-c2ccccc2)no1)NCc1ccc2cc[nH]c2c1 +CCOc1c(OC)ccc2c1CCNC2C1CCC(=O)N1 +COc1ccc(C(=O)N(c2ccccn2)c2ccccn2)cc1OC +COc1cc(C)c(NC(=O)c2cccnc2SC)cc1OC +O=C(NCC1CN2CCCCC2CO1)c1cnc2sccn2c1=O +Cc1ccccc1CC(=O)N1CCC(Nc2cccnc2)CC1 +COC(=O)C1CCN(C(=O)CSc2ccc3ccccc3n2)CC1 +Cc1cccc(OCCN(C)C(=O)NCC(=O)N2CCCCC2)c1 +C=CCN1C(=O)C2C3CC4C(OC1(c1ccccc1)C42)C3O +CN(CCc1cn[nH]c1)Cc1nc(Cc2cccc(F)c2)no1 +Cn1ncc2c(N3CCCC3C3CCCCC3)ncnc21 +COc1ccc(C2NC(=O)c3ccccc3N2)cc1Br +Cc1nn(CC(=O)N(C)C(C)c2ccncn2)c(=O)c2ccccc12 +COc1ccccc1CNC(=O)c1cc(C)nc(N2CCOCC2)n1 +COC(=O)C1CCCCN1Cc1ccc(F)c(Cl)c1 +CCN(Cc1noc(C2CC2)n1)C(=O)c1cc(CC(C)C)on1 +c1csc(Cc2n[nH]c(SCC3CCCO3)n2)c1 +Cc1ccc(F)c(C(=O)Nc2cc(Br)c[nH]c2=O)c1 +CCOC(=O)c1nnn(-c2nonc2N)c1-c1ccc(OCC)cc1 +CN(Cc1ccccc1)S(=O)(=O)N(C)Cc1ccccc1 +O=C1CN(C(=O)Cc2csc(Nc3ccccn3)n2)CCN1 +CC1Oc2ccccc2OC1C(=O)NCc1ccccc1 +CC1CCCC(NC(=O)NCc2ccccc2-n2ccnc2)C1C +Cc1cc(C)n(NC(=O)c2cc(-c3ccccc3)on2)c(=O)c1 +Cc1noc(-c2ccco2)c1C(=O)NCc1cccc2ccccc12 +Cc1cnc(NC(=O)c2cc(F)cc(F)c2)s1 +Cc1ccc(-n2ncc3c(=O)n(NC(=O)c4ccco4)cnc32)cc1C +CN(Cc1ccccc1F)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CC(C)C(C)(C#N)NC(=O)CN1C(=O)c2ccccc2CS1(=O)=O +Cc1ccc(C(=O)CCC(=O)Oc2ccc(C#N)cc2Cl)s1 +CCCOc1ncccc1CNC(=O)c1ccc(C)[nH]c1=O +Cc1ccccc1COC1CCN(C(=O)c2cc[nH]c2C)CC1 +COCCNc1nc(-c2ccsc2)nc2ccccc12 +Oc1cccc(C2CN(CCN3CCCc4ccccc43)CCO2)c1 +Cc1nc(-c2cccc(NCc3ccccc3N3CCOCC3)c2)n[nH]1 +O=S(=O)(Nc1cccc(F)c1)c1cccc(O)c1 +COc1ccc(OC)c(C2CCCN2c2nccn(C)c2=O)c1 +CC(=O)N1CCC(C(=O)NCCNC(=O)OC(C)(C)C)CC1 +Cc1cnc(CNC(=O)c2ccc(C(C)C)[nH]c2=O)cn1 +CCC1CCN(C(=O)c2ccccc2Br)CC1 +CCc1ccccc1OC1CN(c2ncnc3c2c(C)nn3C)C1 +CC1CCN(C(=O)C(C)Oc2ccc(-n3cnnn3)cc2)CC1 +CC(=O)NC(CC(=O)N1CCOC(C)(C)C1)c1ccc(Cl)cc1 +O=C(NCc1ccccn1)c1cnc2sc3c(n2c1=O)CCCC3 +CCCc1noc(CN(C)c2ccc(F)c(F)c2)n1 +CC(C(=O)N1CCCCC1c1nc(C(C)(C)C)cs1)n1cncn1 +O=S(=O)(c1ccc2c(c1)CCO2)N1CCCc2ccccc21 +COC1CCN(C(=O)c2ccnn2C)CC1Cc1ccccc1 +CCc1nc(CN2CCN(Cc3cnc4cnccn34)CC2)no1 +COc1ccc(C2NC(=O)c3ccccc3N2)cc1OCCCC#N +COc1cccc(-c2cc(C(=O)N(C)CC(=O)NC(C)C)no2)c1 +CC(=O)c1ccc(NC(=O)NC(c2nc(C)cs2)C2CC2)cc1C +COc1ccccc1OCCNC(=O)Nc1cn[nH]c1 +Cc1cccc(NC(=O)CN(C)C(=O)c2cccc(N(C)C)c2)c1C +COc1cc(CO)ccc1OCCc1c(F)cccc1Cl +CCCCOC(=O)C1CCN(S(C)(=O)=O)CC1 +O=C(CC1C=CCC1)N1CCN(C(=O)Cn2cnnn2)CC1 +CNC(=O)NCC(=O)NCC(O)c1cc(Cl)cc(Cl)c1 +Cc1cccc(CSc2nnc(Cc3c(C)[nH]c(=O)[nH]c3=O)o2)c1 +Cc1ccccc1N(CC(=O)N1CCCC(C)C1)S(C)(=O)=O +COC(C(=O)Nc1cc(-c2ccncc2)n[nH]1)c1ccccc1 +O=C(c1ccccc1-c1ccccc1)N1CC(c2ccncc2)C1 +CCCOC(=O)CSc1nnc(-c2ccc(C)cc2)n1N +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NCCOc1ccccc1 +CCCCNC(=O)Nc1cccc(NC(=O)COC)c1 +COc1ccc(CNC(=O)c2cc(-c3cccs3)[nH]n2)cc1OC +Cc1nc(CNc2ccc(-c3ncn(C)n3)cc2)cs1 +CCc1ccsc1C(=O)N1CCN(C(C#N)c2ccccc2)CC1 +CCOC(C)C(=O)N1CCC(OCc2ccccc2F)CC1 +COc1cc(Cl)ccc1C(=O)N(CCC(N)=O)Cc1ccccc1 +CCC(=O)N1CCC(=O)N(Cc2ccc(F)cc2)C(C(C)C)C1 +CC1CCN(C(=O)NCCOc2ccccc2)CC1 +Cc1cc(C)cc(NC(=O)NCC2(O)CCOCC2)c1 +Cc1ccc(NC(=O)CC(C#N)c2ccco2)c(C)c1 +Cc1nn(CCNC(=O)C2CC(=O)N(C(C)(C)C)C2)c(C)c1Cl +CC1CCC(C(=O)NCc2ccnc(OC3CCC3)c2)O1 +C=CCOC(=O)c1cc(N2CCCC2=O)ccc1Cl +CC1CCc2onc(C(=O)NCc3ccccc3)c2C1 +Cc1noc(C)c1C(=O)OCc1coc(-c2ccccc2)n1 +COc1ccc2nc(NC(=O)C(OC)c3ccccc3)sc2c1 +Cc1ccc(S(=O)(=O)Nn2nnc3ccccc3c2=O)cc1 +CCCC(C)C(=O)N1CCCC(C(=O)OCC)C1 +COc1cccc(CNC(=O)NC2CCN(c3ncccn3)CC2)c1 +CCCc1n[nH]c(N)c1-c1nc2ccccc2s1 +Cc1ccsc1CNC(=O)Cn1cc(C(F)(F)F)ccc1=O +CCc1nnc(CNc2nc(C)nc3sccc23)o1 +Cc1cc(C(=O)NC(C)c2noc(Cc3ccccc3)n2)[nH]n1 +Cc1cc(OCCCC(=O)NC(C)c2ccncc2)ccc1Cl +CC(CC#N)Sc1ccccc1NC(=O)Cc1ccc[nH]1 +CC(C)CC(=O)Nc1cc2c(cc1SC(C)C)n(C)c(=O)n2C +CNC(=O)CN1CCN(C(=O)C2(c3cccc(F)c3)CCC2)CC1 +Cc1cc(C)c(C)c(S(=O)(=O)N2CCC(n3ccnc3)CC2)c1C +O=C(c1cccc(-n2cnnn2)c1)N1CCCCCC1 +NC(=O)c1csc(Nc2ccc(OC(F)(F)F)cc2)n1 +CC(C)Cc1nc2cc(Br)c(N)cc2[nH]1 +CCN1CC(C(=O)Nc2c(F)cccc2N2CCCC2)CC1=O +CCCN(CC(=O)NC)C(=O)C(C)Oc1ccc(Cl)cc1Cl +CC(NC(=O)CCn1cccn1)c1ccccc1C(F)(F)F +CCOc1ccc(F)c(C(=O)N(C)C(CC)c2ccncc2)c1F +CCCCN(CCO)C(=O)Nc1ccccc1N1CCCC1 +Cc1cc(NC2(c3ccccc3)OC(=O)c3ccccc32)no1 +O=C1CCCN1c1ccc(NCc2nnc(C3CCC3)o2)cc1 +CNC(=O)COC(=O)Cc1c(C)nn(-c2ccc(Cl)cc2)c1C +COC(=O)c1ccc(CN2CCOc3ccccc32)o1 +CSc1ccc(NC(=O)Cn2cc(Nc3ncccn3)cn2)cc1 +O=C(Nc1ncc(C#CCCO)s1)C1CCCCC1 +COc1ccccc1CN(C1CC1)S(=O)(=O)c1ccc(C#N)cc1 +CCN(CCC(=O)OC)C(=O)c1nc2nccc(C)n2n1 +Cc1ccc2oc(C(=O)c3ccncc3)c(C)c2c1 +Cn1c(=O)[nH]c2cc(C(=O)N(CCC(N)=O)c3ccccc3)ccc21 +O=C(NCc1cnn2ccccc12)c1ccc2ncsc2c1 +CN(C)C(=O)c1cc(NCc2noc(-c3cccs3)n2)ccc1F +N#Cc1ccccc1NC(=O)c1ccc(=O)n(Cc2ccc(F)cc2)c1 +CCCc1c(C#N)nnn1-c1ccc(C(=O)OCC)cc1 +O=c1c2nnc3ccnn3c2ncn1CCc1cccs1 +COCCn1nc(C)c(CNC(=O)Cc2ccc[nH]2)c1C +Cn1nc2n(c1=O)CCN(Cc1cccc(Cl)c1)C2 +Cc1ccsc1CNC(=O)c1cc(Br)c[nH]1 +CC(C)(C#N)NC(=O)CN1C(=O)CSc2ccccc21 +CCCNc1nnc(-c2cnc(C3CCCO3)s2)s1 +CC(CC1CCCC1)C(=O)N(C)CC(=O)N(C)C +CC(=O)c1cc(CC(=O)NCc2ccc(C)s2)cs1 +Cc1c(C(=O)N2CCc3cc(F)ccc3C2)c(=O)oc2ccccc12 +CC1CN(CC(O)c2cccc(F)c2)CC(C)O1 +CC(C)C(C)N(C(=O)NC1CC(=O)N(CC(F)(F)F)C1)C1CC1 +CC(O)CN(CC(C)O)C(=O)CCc1ccccc1 +CCOC(=O)CCC(=O)N1CCCC1c1cccs1 +CN1CC2CCN(C(=O)c3ccc(Cl)cc3)CCC2S1(=O)=O +Cc1cc(N2CCN(C(=O)c3ccc(F)cc3)CC2)n2ncnc2n1 +O=C(Cn1c(=O)cnc2ccccc21)N1CCCC(C(F)(F)F)C1 +COc1ccc(OC)c(CNC(=O)c2cc(C)on2)c1 +CCOC(=O)c1ncn(C(C#N)C(=O)OCC)c1N +COCCNC(=O)c1cccc2c(=O)c(C)c(-c3ccccc3)oc12 +CC(NC(=O)C(C)n1cccn1)c1ccc2c(c1)CCC(=O)N2 +CN(C)C(=O)N1CC2CN(S(C)(=O)=O)CCOC2C1 +CCNC(=O)N1CCN(CC(=O)N(C)Cc2ccccc2F)CC1 +CN1CCN(Cc2ccccc2OC(F)(F)F)C1=O +COCCN1CCN(S(=O)(=O)c2ccc(F)c(C)c2)CC1=O +CCCCOC(=O)c1sccc1S(=O)(=O)N1CCCCC1 +OCCCSc1nc(COc2ccc(Cl)cc2)n[nH]1 +Cc1n[nH]c2ncc(C(=O)NCc3cn(-c4ccccc4)nn3)cc12 +CCC1c2ccsc2CCN1C(=O)C1CCCN(C(N)=O)C1 +CSc1cc(-c2ccccc2F)oc(=O)c1C#N +CCCNC(=O)Cn1nc(-c2cccs2)c2ccccc2c1=O +Cc1noc(C)c1COC(=O)CCc1nc(-c2ccc(F)cc2)no1 +Cc1ncc(CNC(=O)c2cc(Cl)c[nH]2)s1 +CCCCNC(=O)NCCn1nc2ccccn2c1=O +CC(Nc1nc2nonc2nc1N1CCCCCC1)c1cnn(C)c1 +COc1ccc(CC(C)C)cc1S(=O)(=O)N1CCNCC1 +COCc1ccc(CNC(=O)N(C)Cc2ccc3c(c2)OCO3)cc1 +CC(O)c1cccc(NCc2ccc(O)c(F)c2)c1 +O=C(Nc1cn[nH]c1)c1ccc(CSc2ccccc2)cc1 +COc1ccccc1CC1CNc2cc(O)ccc2O1 +CCNC(=O)c1ccc(-n2cnc3ccccc3c2=O)cc1 +CCc1nnc(NC(=O)CSc2ccc(C)c(C)c2)s1 +CC(C)C(=O)NCCCS(=O)(=O)c1ccccc1 +CCOCCS(=O)(=O)c1ccc(NC(C)=O)cc1 +Cc1noc(C)c1S(=O)(=O)NC(C)C(=O)NCc1ccco1 +Cc1cc(CN(C)C(C)c2nc3sc(C)c(C)c3c(=O)[nH]2)no1 +COc1ccc(CN2C(=O)C(C)CS2(=O)=O)cc1C(C)C +Cc1cnc2n(c1=O)CC(C(=O)N1CC(C)OC(C)C1)CS2 +CCOC(=O)c1c(NCCN2CCOCC2)c2ccccc2[nH]c1=O +Cc1ccc(C(N)=O)cc1NS(=O)(=O)c1cccs1 +CC(=O)Nc1cc(S(=O)(=O)Nc2ccc3c(c2)CCC3)ccc1F +CCN(C(=O)c1ccc(C)nc1N)c1cccc(C)c1 +CCCCCn1nc(CO)cc1-c1cccs1 +COc1ccc(C(=O)Nc2cc(C)n(Cc3ccc(F)cc3)n2)cc1 +COc1ccnc(NC(=O)Cc2ccc(NC(=O)C3CC3)cc2)c1 +C#CCNC(=O)COC(=O)c1ccc(S(C)(=O)=O)cc1 +COC(=O)C1CCCC1NC(=O)Nc1cc(-c2nnco2)ccc1C +Cc1nnc(Cc2cccc(Br)c2)s1 +CCN1CC(C(=O)OCC(=O)N2CCCc3ccccc32)CC1=O +Cc1nn2cccnc2c1C(=O)N1CCCC(Nc2ccccc2)C1 +Cc1nc(C)n(CC(=O)Nc2ccc(C)c(C)c2)n1 +CCNc1nc(C)c(C(=O)N2CCNCC2C(=O)NC2CC2)s1 +CCn1c(SCCOC(C)C)nnc1C1CC1 +Nc1cccnc1SCC1COC2(CCCC2)O1 +O=C(Nc1ccc(Cl)cc1)c1ccc2c(c1)OCO2 +CCCn1ncc(S(=O)(=O)NCCOC)c1N +COc1ccc(CNc2nc(C(=O)NC3CC3)cs2)cc1 +COc1cccc(OCC(=O)NC(C)c2ccccc2)c1 +CC(C)(C)c1ncc(C(=O)N2CCCCC2)c(N)n1 +CC(CC#N)N(C)C(=O)Nc1cccc(C(=O)N2CCOCC2)c1 +O=C(C1CCCO1)N(Cc1nnc(-c2ccc(Cl)cc2)o1)C1CC1 +CC(Cc1ccc(O)cc1)NC(=O)N1CCOCC1 +Cc1ccc(=O)n(CC(=O)Nc2ccccc2C)n1 +CC(C)c1nc2ccc(NC(=O)c3ccccn3)cc2[nH]1 +O=C(CCC1CCCC1)N1CCc2sccc2C1 +NC(=O)Nc1ccc(C(=O)NCCOc2ccccc2)cc1 +Cc1ccc(CCNC(=O)c2ccc(CCC(C)(C)O)cc2)o1 +Cn1ncc2c(NCCc3cccs3)nc(N3CCCC3)nc21 +Cc1ccc2c(c1)N(CC(=O)NCc1cccs1)C(=O)CO2 +CCOc1ccc(C(C)NC(=O)CCn2ccccc2=O)cc1 +CNC(=O)c1cccc(CCNC(=O)N2CCc3ccccc32)c1 +Cc1ccsc1C(=O)NCc1nc(-c2ccco2)n[nH]1 +Cc1nonc1NC(=O)c1ccc(-c2cscn2)cc1 +Cc1oncc1C(=O)N1CCCC2(CCN(c3ccccc3)C2=O)C1 +COc1ccc2ccn(CC(=O)Nc3ccc(C)c(C)c3)c(=O)c2c1 +Cc1occc1C(=O)NCCn1ncc2c1c(C)nn2C +O=C(C1CCC1)N1CCN(c2ccc(F)cc2)CC1 +O=C(CCS(=O)(=O)c1ccccc1F)Nc1ccccc1F +O=C(COc1ncnc2ccccc12)NCC1CCCCC1 +COC(=O)c1cc(CNC(=O)NC(C)c2cccs2)ccc1OC +C#CCN1CCN(C(=O)NC2CCc3nc(C)nn3C2)CC1 +CCS(=O)(=O)c1ccc(NC(=O)NCCCC(C)C)cc1 +CCCCC(O)c1ccc2c(c1)CN(C(C)=O)CC2 +COc1ccc(OCC(O)CN2CCN(c3nccs3)CC2)cc1 +CC(=O)NC(C(=O)NC(C)c1cccc(Br)c1)C(C)C +CN(C)C(=O)c1ccc(NC(=O)COc2ccc(C#N)c(F)c2)cc1 +CNC(=O)C(C)(C)CNC(=O)c1cn(C)nc1C(C)(C)C +Cc1ccc(NC(=O)C(C)Oc2cccc(N)c2)cc1C +O=C(CNC(=O)c1cccs1)NCCNC(=O)c1ccc(F)cc1 +Cn1c(C(=O)Nc2cccc(C(N)=O)c2)cc2c(F)cccc21 +CC(=O)c1cccc(NC(=O)CCc2cccs2)c1 +Cc1c(C(=O)N(C)CC(F)(F)F)cnn1-c1ccccc1 +CCc1noc(C(C)Sc2nc(-c3cccnc3)n[nH]2)n1 +CN1CC(C(=O)N(C)C2CCc3ccccc3C2)CC1=O +CC(O)CNC(=O)c1cccc(Oc2ccccc2)c1 +Cc1nc2sccn2c1-c1[nH]cnc1-c1ccccc1 +COc1c(C2CCCN2C(=O)Cn2nc(C)cc2C)c(C)nn1C +CCN(CC(C)C#N)C(=O)CNc1c(C)cccc1C(N)=O +Cc1ccc(CNC(=O)N(Cc2ccco2)CC2CCCO2)s1 +Cc1nn(C)c(C)c1CC(C)NC(=O)Nc1ccc(C2CC2)nn1 +CCCNC(=O)C1CCCN(C(=O)NC(C)c2cc(C)oc2C)C1 +O=C(CCN1C(=O)COc2ccccc21)NCCOc1ccccc1 +CC(C)CNc1nnc(S(=O)(=O)CC(N)=O)s1 +CCCCNC(=O)NCc1noc(-c2ccsc2)n1 +Cc1nnc(Cc2ccc(-c3cccc(CO)c3)cc2)o1 +CC(=O)N1CC(C(=O)N=c2[nH]cc(-c3ccccc3)n2C)C1 +CC(=O)Nc1ccc(NC(=O)c2csc(NC3CC3)n2)cc1 +N#Cc1ccccc1OCC(=O)Nc1cc(Br)ccc1F +COC(=O)CNC(=O)c1cc2cc(F)ccc2[nH]1 +CC(C(=O)Nc1cccc(N2CCCC2=O)c1)N1CCOCC1 +CCCOc1cccc(C(=O)Nc2cccc(OC(C)=O)c2)c1 +CC1(C)CCC(CNC(=O)CCOCC2CCCO2)CC1 +CSc1sc(-c2ccon2)c(-c2ccco2)c1C#N +O=C(Nc1cnc(-c2ccccc2)nc1)c1cccc2cn[nH]c12 +CC(=O)Nc1ccc(NC2CCSc3ccccc32)cc1 +COC(=O)N(C)c1ccc(NCC(C)(C)C)cc1 +NC(=O)c1cccc(CNC(=O)c2cc3ccccc3s2)c1 +Cc1cc(C(=O)Nc2sc3c(c2C#N)CCC3)nn1C +COc1cccc(C(=O)NC2CCN(C(=O)CC(C)C)CC2)c1F +CC1=C(C(=O)Nc2ccc(F)cc2)C(c2ccc(O)cc2)NC(=O)N1 +CC(NC(=O)NCc1nnc2ccccn12)C(C)(C)c1ccccc1 +O=C(CCCn1nnc2ccccc2c1=O)N1CCCCC1 +COCCOc1ccc(CNc2ncnc3sccc23)cc1 +CCC(CC)C(=O)NCc1nn(C)c2c1CCCC2 +CN(C)C(=O)CCc1cnc(C2CCCN2S(C)(=O)=O)cn1 +CCOc1ccccc1N1CCN(C(=O)c2ccccc2C)CC1 +CCCC1=C(C(=O)OCC)C(c2ccccn2)NC(=O)N1 +COc1ccc(NC(=O)C2CC2c2ccco2)cc1 +Cc1cccc(CN2CCc3ncnc(-c4cccnc4)c3CC2)n1 +Cc1ccccc1CSc1nnc(SCC(N)=O)s1 +CNC(=O)C1Cc2ccccc2CN1Cc1nc(C(C)(C)C)no1 +CC(=O)Nc1ccc(C2=NC3=Cc4ccccc4OC3O2)cc1 +C=CCOc1c(N)cc(Cl)cc1Br +COCCCC(=O)Nc1nc(-c2ccc(C)cc2)n[nH]1 +COc1cc(CO)cc2c1OCC(=O)N2CC(=O)N1CCCC1 +CCn1c(SCC(=O)NC2CCOCC2)nnc1-c1ccco1 +COC(=O)c1ccc(-c2noc(-c3cnc(C)s3)n2)cc1 +CCn1cc(S(=O)(=O)N2CCc3ccccc32)cn1 +Cc1nn(CC(N)=O)c(C)c1S(=O)(=O)N1CCCCC1 +O=C(CCN1CCOC1=O)Nc1ccnn1-c1cccc(Cl)c1 +CC(C)c1ccc(-c2nc(C(=O)NCCO)cs2)cc1 +CC(C)(CNC(=O)OC(C)(C)C)NC(=O)C1CC2CCC1O2 +Cc1cn2nc(N(C)Cc3cccs3)sc2n1 +CNC(=O)Cc1noc(CCCn2ccc3cc(Cl)ccc32)n1 +Cc1cc(N)nc(SC(C)C(=O)N(CCC#N)c2ccccc2)n1 +CC1CN(C(=O)NCc2nccn2Cc2ccccc2)c2ccccc21 +COc1ccccc1NC(=O)CCc1nc2ccccc2[nH]1 +CC(=O)c1ccc(C)cc1OCC(=O)N(C1CC1)C(C)C1CC1 +O=C(CCOc1ccc(F)cc1)NCc1ccncc1 +CSc1n[nH]c2ncnc(Nc3ccc(C)cc3)c12 +Cc1ccn(-c2ccc(C(=O)NCc3ccc(F)c(Cl)c3)cn2)n1 +c1cc(CNc2nc(C3CC3)no2)c2[nH]ncc2c1 +OCc1c(N(CC(F)(F)F)C2CC2)nc2sccn12 +Nc1cc(NC(=O)CCn2cc(Cl)cn2)ccc1F +CCCc1nc(CN2CCN(c3nccs3)CC2)cs1 +CC(C)c1ccc(C(=O)Nc2ncccc2O)cc1 +Cc1nc2ccccc2n(Cc2noc(C(C)C)n2)c1=O +CCN(CC(=O)OC)S(=O)(=O)c1ccccc1OC +Cc1ccc(OCC#CCNC(=O)c2ccc(C(F)(F)F)cc2)cn1 +COc1ccc2nc(C(=O)Nc3cc(C#N)ccc3Cl)ccc2c1 +CC(C)CS(=O)(=O)NCC1CCN(C(=O)c2ccoc2)CC1 +Cc1oc(-c2ccsc2)nc1CC(=O)NCC(=O)N1CCCC1 +N#Cc1c(F)cccc1N1CCc2c(N)cccc2C1 +Cc1oc(C)c(C(=O)NCCC(=O)N2CCc3sccc3C2)c1C +CC(NCC(=O)NC1CCCCNC1=O)c1ccc(F)c(Cl)c1 +CC(C)C(=O)NCCNC(=O)Nc1ccc(F)c(Br)c1 +Cc1ccc2nc(-c3ccc4c(c3)ncn4C)c(N)n2c1 +COc1ccc(CCNC(=O)Nc2nncs2)cc1 +CC(C)N1CC(C2NCCc3cc(F)ccc32)CC1=O +CC(C)Oc1ccccc1CC(=O)NCC(C)(C)c1ccncc1 +CC(C)C(=O)NCCNS(=O)(=O)c1ccc(Cl)cc1 +CC(C)OC(=O)c1cc(-c2ccc(O)c(N)c2)nn1CCO +CCCCNC(=O)N(C)Cc1cc(C(=O)OC)c(C)o1 +Cc1ccc(C(=O)CCC(=O)N(C)c2ccccc2)cc1N +O=C(NCc1cccnc1-n1cncn1)c1ccccc1-n1cccn1 +CC1CN(C(=O)CSc2ccccc2)C(C)CO1 +CCCN(CCC)C(=O)c1ccc(Cl)cc1N1CCCC1=O +CCS(=O)c1ccccc1C(=O)NCC(C)c1c(C)noc1C +CC1Cc2cc(CN(C)Cc3nc4ccccc4c(=O)[nH]3)ccc2O1 +O=C(c1cc(Cl)c[nH]1)N1CCC(CN2CCOCC2)CC1 +CCOc1ccc(CNC(=O)c2cn[nH]c2-c2cccs2)cc1 +Cc1cc(OCC(=O)NCCS(N)(=O)=O)ccc1C(C)C +Cc1csc(C2CCCCN2C(=O)c2occc2C)n1 +O=C(Cc1ccc[nH]1)NCc1ccc(Cl)cc1Cl +COc1ccccc1-c1n[nH]c(C2CC2)c1NC(=O)c1ccccc1 +O=C(CSc1nn(-c2ccccc2)c(=O)[nH]1)Nc1cccc(F)c1 +O=c1[nH]c(C2CC2)ncc1-c1ncnn1C1CCCCC1 +COc1cccc(CC(=O)N2CCC(C(=O)c3cccnc3)CC2)c1 +COc1ccc(C2(C)CNC(=O)O2)cc1Br +CCN(Cc1ccc(OC)c(F)c1)c1cc(C)nc2ncnn12 +COc1ccc(C)cc1CN(C)C(=O)CNC(N)=O +COC(=O)C(C)n1cc(CO)c2cccc(OC)c21 +CCOC(=O)C1=C(C)C(C(=O)OCC)C(C#N)=N1 +CC(c1nnnn1-c1ccccc1)N1CCc2cc(F)ccc2C1 +Cc1cn(C2OC(CO)C(O)C2O)c(=O)nc1N +NC(=O)Nc1cccc(CNC(=O)C2CC2c2ccc(F)cc2F)c1 +CCCC(=O)N1CCC(C(=O)NC2(c3noc(C)n3)CCCC2)CC1 +CCOC(=O)CCC(C)NC(=O)C1(C#N)CCC1 +Cc1noc(C)c1C(C)NC(=O)CCSc1ccccc1Cl +Cc1oc(C)c(C(=O)N2CCCC(N3CCNC3=O)C2)c1C +CCc1ccc(C(=O)N2CCC(C)(O)C(C)(C)C2)[nH]1 +CCN(CC1COc2ccccc2O1)C(=O)C1CCCO1 +CCN1CCN(C(=O)C2N=C(C)C=C2C)CCC1=O +O=C(Cc1ccc(F)cc1F)Nc1ccccc1F +CCOC(=O)CCNC(=O)c1c(C)oc2ccc(OC)cc12 +C#CCNC(=O)c1cccc(Oc2ccc(C#N)cc2)c1 +Cc1[nH]c2ccccc2c1C(=O)N1CCNC(=O)C1 +CC(C)c1cc(=O)[nH]c2cc(NC(=O)c3ccccc3)ccc12 +CN(C)C(=O)CNC(=O)c1c[nH]cc1-c1ccccc1 +c1cc2c(cc1NCc1c[nH]nc1-c1ccc3c(c1)OCCO3)COC2 +CCc1noc(CC)c1CC(=O)NC(C)c1nc2ccccc2[nH]1 +CC(Sc1nc2ccccc2n1C)C(=O)Nc1ccnn1C(C)C +COC(=O)c1cc(-c2ccc(Br)cc2)n[nH]1 +CCCCCSc1nnc(C(C)(C)C)c(=O)n1N +Cc1nc(C)c(C(C)NC(=O)C2CCOC2)s1 +CCCNC(=O)C(C)NC(=O)NCc1nc(C)cs1 +OCCCCNc1cc(-c2ccccc2F)nc2ccnn12 +CC(=O)N1CCC(C(=O)NCc2cn3cc(Cl)ccc3n2)CC1 +Cc1ccc(F)c(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)c1 +COc1cc(NC(=O)NC(C2CC2)C2CC2)cc(OC)c1 +CCOc1ccc(NC(=O)c2cnc(C3CC3)nc2N)cc1 +Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1C1OC(=O)c2ccccc21 +Cc1csc(NC(=O)N(Cc2ccco2)Cc2ccco2)n1 +CCc1ccc(C(=O)NC2CCCn3nc(CC)nc32)cc1 +Cn1cc(NC(=O)c2ccccc2Br)ccc1=O +COc1cccc(N2CC(Nc3cc(C)nc4ccnn34)CC2=O)c1 +C=CCNC(=O)CCn1c(=O)oc2ccc(Cl)cc21 +NC(=O)NCCCCC(=O)Nc1nc(-c2ccccc2)ns1 +N#CCc1ccc(NC(=O)c2c[nH]c3cccc(F)c23)cc1 +N#Cc1ccccc1OCC(=O)NCc1ccnc(OC2CCC2)c1 +COCCOc1cccc(C(=O)N2CCC(Nc3ccccc3)C2)c1 +COCCNC(=O)c1onc(-c2ccncc2)c1N +NC(=O)c1cccc(NC(=O)CSc2ccccc2)c1 +CCOC(=O)Nc1c(O)cccc1N1CCCC1 +CN(CC1CCCN(S(C)(=O)=O)C1)c1cnn(C)c1 +CCC(CC)C(=O)NCC(C)(C)N1CC(C)OC(C)C1 +CCn1nc(C(C)C)cc1C(=O)NCc1cc(C2CC2)on1 +CC(C)(C)C(=O)CNC(=O)CNC(=O)c1cccs1 +Cc1cc(CNC(=O)c2cc(CN3CCOCC3)on2)n[nH]1 +COc1ccccc1C(C)NC(=O)c1ccc(OC(C)=O)cc1 +Fc1cccc(C2(c3nc(C4CCOC4)no3)CCC2)c1 +COc1ccc2c(c1)C(NCC(O)c1ccsc1)CCCO2 +Cc1ccc(NC(=O)C2Cc3cc(Cl)ccc3O2)nc1 +COc1ccc(CCC(=O)N2CCN(C3CCCC3O)CC2)cc1 +O=C1CCCC2C3CC(CN(c4ncccc4C(F)(F)F)C3)CN12 +CCc1cccc2c1N(Cc1nc(CCOC)no1)CCC2 +Cc1ccc(Cl)c(NC(=O)COC(=O)c2cnccn2)c1Cl +CC1CCN(S(=O)(=O)NCCc2cccs2)C1 +Cc1ccc(-c2cnc(CCC(=O)Nc3cc(C)on3)o2)cc1 +Cc1ccc(OCCc2nc(CCCO)cs2)c(C)c1 +CC(=O)Nc1ccc(-c2nc3c(F)cccn3c2N)cc1 +COCCc1noc(CN(C)C(=O)Nc2ccnn2C(C)C)n1 +CC(=O)c1c(C)nn(-c2ccc(OC(C)C(N)=O)cc2)c1C +C=CCNc1nnc(SCC(C)C(C)=O)s1 +Cn1ccc(C(=O)Nc2ccc(F)c(F)c2)cc1=O +O=C(Cc1cccc(F)c1)Nc1nc(-c2ccccn2)cs1 +O=C(CCN1CCOC1=O)Nc1ccc(Br)cc1Cl +Cn1nnnc1SCCC(=O)NC(C)(C)c1cccc(F)c1 +COCCn1ccc2cc(Nc3cnn(C)c(=O)c3Cl)ccc21 +CCC(Nc1ncnc2nc(C)cc(C)c12)c1ncnn1CC +Cc1ccc(C(=O)N2CCN(C(=O)Nc3ccncc3)CC2)o1 +Oc1cccc2c1CCNC2c1ccc(C(F)(F)F)nc1 +CS(=O)(=O)c1ccc(OCCCC(=O)N2CCCCCC2)cc1 +O=C(CCc1ccc(Cl)cc1Cl)NCc1ccoc1 +CCCCNC(=O)NC1CCCc2[nH]c(=O)ccc21 +Cc1cccc(NC(=O)Cn2nc3cnc4ccccc4n3c2=O)c1C +CC(C)(CNC(=O)NCc1ccc2c(c1)CCC2)N1CCOCC1 +O=C(NCc1cscn1)c1cccc(NC(=O)c2cccnc2)c1 +CCS(=O)(=O)NCCCNC(=O)NC1CC2CCC1(C)C2(C)C +CN(C)C(=O)c1cccc(NC(=O)CN(CCO)c2ccccc2)c1 +O=C(CNC(=O)c1cnccn1)NCCc1cc2cc(F)ccc2[nH]1 +Cn1cc(CCC(=O)NCC2(c3c(F)cccc3F)CCCC2)cn1 +Cc1c(NS(=O)(=O)c2ccc(Cl)cc2)cccc1-n1cnnn1 +CC1(O)CN(Cc2ccccc2)C(c2ccccc2)CC1=O +Cc1noc(C)c1CC(=O)N(Cc1cccnc1)C1CC1 +CCN(CC)C(=O)c1ccc2c(c1)[nH]c(=O)c1ccncc12 +CCCCCn1cccc(-c2nnc(NC)s2)c1=O +CSc1nnc(SCC(=O)c2ccc(O)cc2O)s1 +O=C(NCc1ccco1)NCC(O)C(F)(F)F +Cc1nc(C)c(C(=O)N2CCC(c3cc(O)nc(N(C)C)n3)C2)o1 +COc1ccccc1COC(=O)CC(C)c1ccccc1 +O=C(NCC(O)CO)OCc1ccccc1Cl +Cc1cc(NCc2ccncc2)nn1-c1cccc(F)c1 +COC(=O)c1cc(-c2ccc(OC)c(OC)c2OC)on1 +CN(C)S(=O)(=O)NCC(=O)c1ccc(Cl)cc1 +CCOC(=O)CCNC(=O)c1cc2cc(C)ccc2[nH]1 +CN(CC1CCCO1)C(=O)NCc1cccc(NC(=O)C2CCC2)c1 +Cc1nc(C2CCCN2C(=O)CCn2nc3ccccn3c2=O)no1 +CC(=O)Nc1ccc(C)c(NC(=O)c2ccnc(OC3CCC3)c2)c1 +CCCOc1cc(C)ccc1NC(=O)CCC(=O)N1CCOCC1 +Cn1nccc1C1(O)CC2CCC(C1)N2C(=O)c1cc(C2CC2)on1 +O=C(NC1CCOc2ccccc21)c1cc(=O)[nH]c2ccccc12 +O=C(CC1CCCCO1)Nc1ccc2c(c1)OCC(=O)N2 +CCOc1ccc(NC(=O)C(C)Sc2cc(C)nc(C)n2)cc1 +CN(C)c1nc(CNC(=O)NC2(C)Cc3ccccc3C2)cs1 +Cc1cc(C(=O)N2CCC(Nc3cccn4ncnc34)CC2)nn1C +Cc1cc2c(=O)n(NC(=O)c3cn(C)nc3C)c(C)nc2s1 +C=CCOC1CN(C(=O)c2cccnc2OC)C2CCCOC12 +CCCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(C)o1 +CCCNC(=O)C(C)n1cc(Br)cn1 +Cc1csc(NC(=O)CC(O)(c2nccn2C)C(F)(F)F)n1 +Cc1c(CCC(=O)Nc2sccc2C(=O)C(C)(C)C)cnn1C +COc1cccc(C(=O)N(C)Cc2cccc(Cl)c2)c1 +CN1C(=O)c2sc(-c3ccc(F)cc3)c(Cl)c2S1(=O)=O +COCC(NC(=O)c1cc(-c2cccs2)n[nH]1)C(N)=O +O=C(c1c[nH]c2cccc(F)c12)N1CC2CCC1C2 +Brc1cccc(Oc2ccncn2)c1 +N#CC1(NC(=O)CN2C(=O)CSc3ccccc32)CCCCC1 +Cc1cc(-c2ccc(F)c(Cl)c2)cn2nc(N)nc12 +CCC(NC(=O)c1c(C)cc(C)cc1C)c1nccs1 +CCC(NC(=O)NCC(C)(C)c1ccncc1)c1c(C)nn(C)c1C +Cc1cccc(NC(=O)N(C)Cc2cnn(-c3ccccc3)c2)n1 +COc1ccccc1CCC(=O)Nc1nccs1 +Cc1cc(C(=O)N(CC(C)C)C(C)C)c2nc3n(c2n1)CCCCC3 +O=C(c1cc(Cl)ccc1Br)N1CCCC1 +CC(Nc1ccc(C#N)c(Cl)c1)c1nnc2ccccn12 +NC(=O)c1cnc(NC(=O)c2scnc2C2CC2)s1 +COc1ccc(NS(=O)(=O)c2ccccc2)cc1 +CN(CC(=O)N1CCN(Cc2ccncc2)CC1)c1cnccn1 +CS(=O)(=O)NC1CCN(C(N)=O)C1Cc1ccccc1 +O=C(NCc1ccc2c(c1)OCO2)NCc1cc[nH]n1 +C#CCC(OC(=O)c1cccc(S(C)(=O)=O)c1)c1ccccn1 +Cc1ccccc1NC(=O)c1cccc(S(=O)(=O)N(C)C(C)C)c1 +CCOc1nnc(CN(C)CC(=O)Nc2cc(C)on2)s1 +CCc1nnc(CN2CCN(CCOc3cccc(C)c3)CC2)n1C +COC(=O)c1c(-c2ccc(Cl)cc2Cl)noc1N +Cc1ccc(-n2nnnc2NC2CCc3nc(C)nn3C2)cc1 +CCc1noc(CC)c1CNC(=O)C1CCN(CC(F)(F)F)CC1 +Cc1n[nH]c(C)c1CCC(=O)N1CCc2c(nc(N(C)C)[nH]c2=O)C1 +CCS(=O)(=O)c1ccc2oc(Cn3c(C)csc3=O)nc2c1 +O=C(COc1ccc(Cl)cc1)Nc1ccc2c(c1)COC2 +CN(Cc1ccc(F)c(F)c1)C(=O)NCC(F)(F)F +Nc1c(-c2cccnc2)noc1C(=O)n1cnc2ccccc21 +CCC1CN(C(=O)Cc2ccc3c(c2)OCO3)CCC1(C)O +Cc1ccc(C(=O)N(Cc2ccccc2)C(C)C)cc1O +CC(=O)NC1(C(=O)N2CCN(CC(C)O)CC2)CCCCC1 +CC1CCCCN1C(=O)C1CCN(C(=O)c2ccccc2Cl)CC1 +Cc1ccc(C(=O)Nc2ccccc2C(=O)N(C)C)c(C)n1 +Cc1nc2sc3c(c2c2nc(C(=O)NCC(C)C)nn12)CCC3 +CCC1(C(=O)N(C)Cc2ccc(C(=O)NC)cc2)CCCC1 +CC(=O)Nc1ccc(C(=O)Nc2cnn(-c3ccccc3F)c2)cc1 +Cc1ccc(NC(=O)NC(CCCO)c2ccccc2)nc1 +NC(=O)c1ccc(NC(=O)c2cccc(F)c2N)cc1 +O=S(=O)(NCCc1c[nH]c2ccccc12)c1ccccc1 +COc1ccc(F)c(NC(=O)c2cc(Cl)c(OC)c(OC)c2)c1 +Cc1cc(C2CCCN(C(C)c3nc(C4CC4)no3)C2)n[nH]1 +Cc1ccc(S(C)(=O)=O)cc1NC(=O)NCCC1CCCCC1 +CCOC(=O)C(C)NC(=O)c1nc2nccc(C)n2n1 +CCCn1nc(C)cc1-c1nn2c(-c3cnccn3)nnc2s1 +Cc1cc(C(=O)NCCNC(=O)c2cccnc2)no1 +O=C1C2CCC(CN(c3ncccn3)C2)N1Cc1cscn1 +CCc1nnc(SCc2ncc(-c3cccs3)o2)n1C +CCC(=O)NC(Nc1nccs1)(C(F)(F)F)C(F)(F)F +Cc1ccc(C)n1-c1ncc(Br)cn1 +CNC(=O)C1CCCN1C(=O)NCc1ccco1 +Cc1cc(Cc2ncc(N)cn2)ccc1OC(C)C +N#Cc1cccc(C(=O)NCc2ccc(COCC(F)(F)F)cc2)c1 +COc1ccccc1C(=O)NCc1nc(-c2ccco2)n[nH]1 +C#CCNC(=O)CCCNS(=O)(=O)c1ccc2c(c1)CCCC2 +NC(=O)c1cc(NCc2nc(C3CC3)no2)ccc1F +COc1ncc(NCc2coc(-c3ccccc3)n2)cc1C(N)=O +Cc1cccc(C(=O)NCCCn2cc(Br)c(C)n2)c1 +Cc1ccc(-c2nc(N)n(C(=O)CC(C)C)n2)cc1 +Cc1cc(C(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)on1 +Cc1ccc(C(=O)N(C)CCCc2cc(-c3cccc(F)c3)n[nH]2)o1 +CC(=O)NC(C)C(=O)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1ccc(OCc2nnc3cc(C)c(N)cn23)cc1 +O=C(CCCc1nc(-c2ccco2)no1)Nc1cccnc1 +CCNC(=O)CNc1ccc(C(=O)N2CCCCC2)cc1 +Cc1ccc2ncc(C(=O)OCc3cnn(C)c3)n2c1 +COc1ccccc1CNc1ccc(NC(C)=O)c(OC)c1 +CCn1c(=O)n(CC(=O)N(C)CCC(C)C)c2ccccc21 +COc1ccc(CC(C#N)C(=O)Nc2cccc(OC)c2)cc1 +CC(C)c1nnc(NC(=O)CSc2nnc3n(N)cnn23)s1 +Cc1cc(C)c2c(C(=O)Nc3cnc4n3CCCC4)cc(C)nc2c1 +CCOC(=O)C(NC(=O)c1cnc2ccc(C)cn12)C(C)C +C=CCN1CCN(C(=O)CN2CCOCC2)CC1 +CC(N)C(=O)c1c[nH]c2c(Br)cccc12 +CCOc1cc(OC)cc2c1CCNC2c1cncnc1 +Nc1ccc(-c2cc(C(F)(F)F)ccc2F)cn1 +O=C(NCCCSc1ccccc1)NC1CCCc2occc21 +CN(C(=O)c1ccc(Cl)cc1)c1nnc(-c2cccnc2)s1 +Cc1cc(C(=O)N2CCc3sccc3C2c2cccs2)on1 +COc1ccc(S(=O)(=O)N(C2CCCC2)C2CC2)cc1OC +CCNc1ccccc1S(=O)(=O)N(CC)CCC#N +O=c1[nH]c2ccccc2c(=O)n1Cc1ccccc1Cn1cccn1 +Cc1cc2nnc(-c3cc(N)ccc3Cl)n2cn1 +Cc1[nH]c(NCc2ccccc2Cl)c(C#N)c1C +CC(C)C(=O)N(Cc1ccc(OS(C)(=O)=O)cc1)C(C)C +O=C(Nc1cccc2ccccc12)c1c[nH]c2ccc(F)cc2c1=O +Cc1cc(C(F)(F)F)nc(CN2Cc3ncccc3C2=O)n1 +NC(=O)c1cc(-c2ccccc2)nc2c1cnn2Cc1ccco1 +CC1CN(S(=O)(=O)c2ccc(F)cc2)c2cccnc2O1 +O=C(Nc1cccc(OC(F)F)c1)c1cn2cccnc2n1 +CCCC(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 +Cc1nn(C)c(C)c1NC(=O)CC1Sc2ccccc2NC1=O +Cc1ccc(C)c(C(=O)Nc2ccc3oc(=O)[nH]c3c2)c1 +Cc1nn(C)cc1C(=O)N1Cc2ccccc2N(C)CC1C +COc1ccc(C2CC(=O)c3c(C)nc(N)nc3C2)cc1 +CCCC1C(=O)c2cc(Cl)ccc2N(C)C1=O +Cc1cc(F)cc2[nH]c(C(=O)NCC(O)CN3CCOCC3)cc12 +Cc1cc(C)c(NC(=O)CN(C)c2ccc3nnnn3n2)c(C)c1 +COCc1ccccc1C(=O)Nc1ccc(Cn2ccnc2C)cc1 +CCN(CC(F)(F)F)C(=O)c1cc(F)c(N)c(F)c1 +COC(=O)c1oc(CNC2(CO)Cc3ccccc3C2)cc1C +Fc1ccc(C(F)(F)F)c(CN2CC(c3cccnc3)C2)c1 +Cc1ccccc1-n1ncc2c1CC(C)(C)CC2NC(=O)C1CCC1 +CC(C)N(Cc1cc2ccccc2[nH]c1=O)C(=O)C(C)(C)C +Cc1cccc(C(=O)NC(C(=O)Nc2cc[nH]n2)c2ccccc2)n1 +O=C1NC2(Oc3ccccc31)C(=O)Nc1ccccc12 +COC(=O)c1ccc2c(c1)[nH]c(=O)n2-c1ccc(C#N)cc1 +CCOCCCNC(=O)C1(C)Sc2ccccc2N(C)C1=O +CC(=O)c1sc(NC(=O)c2ccc3c(c2)OCCO3)nc1C +O=C(NCCO)c1cc(-c2ccco2)n(-c2ccc(Cl)cc2)n1 +CC1CCc2ccccc2N1C(=O)Cn1cnc(C#N)c1C#N +Cc1cc(C)c(C(=O)NCCC(=O)OC(C)C)c(=O)[nH]1 +Cc1ccc(NC(=O)NCCc2ccccn2)c(Br)c1 +CC(C)(C)C(=O)N1CCN(CC(=O)NC(C2CC2)C2CC2)CC1 +CN(Cc1cc(C2CC2)on1)C(=O)Cn1sc2ccccc2c1=O +CC(Cc1cnccn1)Nc1cc(N2CCOCC2)ncn1 +COc1ccc(CNC(=O)C(C)Sc2ccccc2F)cc1 +CNS(=O)(=O)c1ccc(CNC(=O)c2ccc[nH]c2=O)cc1 +COC(=O)c1sccc1S(=O)(=O)NCCc1cccnc1 +CC(=O)N1CCc2ccccc2C1C(=O)NCc1ccc(F)cc1F +CCNC(=O)NCC(O)c1ccc(SC)cc1 +CNc1snc(C)c1C(=O)NC1CC1c1cccc(Cl)c1 +CCn1c(=O)c2sccc2n(Cc2ccccc2)c1=O +Cc1ccsc1C(=O)OCC(=O)N(Cc1ccccc1)C(C)C +O=C(CNC(=O)Nc1cnn(CC2CCCO2)c1)NC1CC1 +COC(=O)NCC(=O)Nc1cccc(NS(N)(=O)=O)c1 +CCN(CC(C)C#N)C(=O)c1ccc(OC)c(OC)c1 +Cn1c(CCNC(=O)CCSc2ccccn2)nc2ccccc21 +CCCSc1ncnc2c1cnn2-c1ccc(F)cc1 +O=C(Cc1cn2ccsc2n1)N1CCC(Nc2cccnc2)CC1 +Cn1cc(CC2CCN(C(=O)C3CCCN(C(=O)C4CC4)C3)C2)cn1 +CC(NC(=O)c1ccc[nH]c1=O)C(=O)NC1CCCC1 +CCN(Cc1ccncc1)C(=O)c1cnc2c(c1)nc(N)n2CC +O=C(NC1CC1)c1cccc(NC(=O)N(Cc2ccccc2)C2CC2)c1 +CN(C1CCCCC1)S(=O)(=O)c1ccccc1S(N)(=O)=O +Cc1c(Cl)cccc1S(=O)(=O)NCCC(=O)N(C)C +CCNc1ccc(Cl)c(C(=O)N(C)C(C)C)n1 +CS(=O)(=O)N1CCCC(C(=O)NCc2ccccn2)C1 +COc1cc2c(c(Cl)c1O)C(C(O)CO)NCC2 +CCCc1nc2ccccc2n1C(C)C(=O)N1CCCNC(=O)C1 +CCCCC(=O)Nc1ccc(S(=O)(=O)CC)cc1 +O=C(Nc1ccc2ccccc2n1)Nc1cccs1 +Cc1ccc(F)cc1NC(=O)Cn1c(C)nc2ccccc21 +Cc1ccc(-n2nc(C)c(NC(=O)c3ccccc3)c2C)cc1 +Nc1cccc(OCCn2c(=O)oc3ccccc32)c1 +COc1ccc(CC(C#N)C(=O)NC2CCCC2)cc1O +O=S(=O)(NC1CC1)c1ccc(CNc2cccc(F)n2)cc1 +COC(=O)c1cccc(C(=O)OC2CCCc3ccccc32)n1 +Cc1nnc(NC(=O)N(C)CC2COc3ccccc3O2)s1 +Cc1c(NC(=O)C2CCCC2)cccc1NC(=O)C1CC1 +CCOc1ccc(-n2nnc(C#N)c2C(F)(F)F)cc1 +C=CCNS(=O)(=O)Cc1ccc(Cl)cc1Cl +COCCc1cc(N)n(-c2cccc(Cl)c2Cl)n1 +Nc1cccc(OCCc2nc3ncccc3o2)c1 +CN(Cc1ccccc1F)C(=O)CNc1ccc(C(N)=O)cc1 +Cn1cc(C(=O)OCc2ccc(OCc3nccn3C)cc2)cn1 +CCCNC(=O)c1cccc(NC(=O)Cc2ccc(C)nc2)c1 +Oc1cc(O)c2c(c1)C(c1ccc(F)nc1)NCC2 +CNc1cc(C(=O)N2CCOC(Cc3cccc(OC)c3)C2)ccn1 +Cc1ccc2c(c1)c(=O)c(C(=O)Nc1cccc(C)n1)nn2C +O=C(NCCCO)c1ccc(OCC(F)(F)F)nc1 +O=C(NCC(O)c1ccccc1)c1ccc(-n2cccc2)cc1 +CCc1nnc(SCc2nc(CC(C)C)nn2-c2ccccn2)o1 +CN(CC(=O)N1CCOCC1)C(=O)CN1CCCc2ccccc21 +O=S(=O)(NCCc1ccoc1)c1ccc(OC(F)(F)F)cc1 +CC(NCc1ccccc1Cn1cccn1)C(=O)NC1CCCC1 +COCCCNC(=O)c1ccc(NC(=O)c2cccc(C)c2)cc1 +Oc1ccccc1CCc1nncn1-c1ccc(Cl)cc1 +O=C(c1ccc(N2CCCC2)nn1)N1CCCC1c1cccc(F)c1 +Cc1cccnc1CN(C)C(=O)c1cccc(-c2ccco2)c1 +COC(=O)C1CCCCCC1NC(=O)Cc1c[nH]c2ccc(F)cc12 +Cc1ccc(CNC(=O)Cn2c(=O)c(=O)n(C)c3ccccc32)o1 +CN(C)S(=O)(=O)c1ccc(C(=O)OCC2CCCO2)cc1 +COc1cc(CNC(=O)c2c[nH]nc2-c2cccc(Cl)c2)ccn1 +C=CCOC(=O)c1cc(Br)ccc1F +CC(C)Nc1ccc(C(=O)NC(CO)c2ccccc2)cn1 +COCc1c(C#N)nnn1-c1cccc(Cl)c1C +CN(C)C(=O)CN(Cc1cccc(Cl)c1F)CC(F)(F)F +CCOC(=O)C(Cc1nc2ccccc2n1CC)NC +CCOC(=O)c1cnn2c1nnc1c(=O)n(-c3cccc(C)c3)ccc12 +CC(NC(=O)CSc1nc(N)cc(N)n1)c1ccccc1 +CNC(=O)NC(C)(C)C(=O)Nc1ccc(C)cn1 +Cc1ccc(C)c(OCC(=O)N2CCN(c3ncccn3)CC2)c1 +Cc1nc(N2CCN(CC(C)C)C(=O)C2C)c2cnn(C)c2n1 +CC(C)(C)NC(=O)CSc1nc2ccccc2c(=O)n1N +O=S(=O)(c1ccccc1)N1CC2C=CCC(C=C2)C1 +Cc1nn(-c2ccccc2)c(C)c1NC(=O)COc1ccccc1 +Cc1cc(C)nc(N2CCC(c3noc(C)n3)CC2)n1 +CCN(CC)C(=O)Cn1cc(C(=O)N2CCc3n[nH]cc3C2)nn1 +O=C(CCC1CCCO1)NCc1ccnc(-n2cccn2)c1 +Cn1c(C(F)(F)F)nc2c(F)c(F)c(F)cc21 +CSc1ccc(Cl)cc1NC(=O)C1CC=CC1 +CSc1nc(C)c(CCC(=O)Nc2cccc(C)c2)c(=O)[nH]1 +O=C1NCCN1C1CCCN(c2cccc(F)n2)C1 +CC(C)C(NC(=O)c1ccco1)C(=O)Nc1cccc(F)c1F +CC(C)(C)n1cc(NC(=O)c2ccc(OC(F)(F)F)cc2)cn1 +Cc1c(CCC(=O)NCc2ccoc2)c(=O)[nH]c2c1c(=O)[nH]n2C +NC(=O)C(Cc1ccccc1)NC(=O)c1csc(-c2ccco2)n1 +Nc1cccc(-c2csc(NC(=O)c3ccc4c(c3)OCO4)n2)c1 +O=C(Nc1ccccc1C(=O)N1CCCC1)c1cc2ccoc2s1 +COc1ccc(C(=O)N(C)C)cc1NCC(=O)N(C)C1CC1 +CN(Cc1ccccc1)C(=O)c1cc2cccnn2n1 +O=C(NCCn1ccnc1)c1cccc(NC(=O)c2ccco2)c1 +CC1CN(C)c2ccccc2CN1c1ncccn1 +CC(=O)N1CCN(Cc2nc3cc(F)c(F)cc3[nH]2)CC1 +CCn1ccc(NC(=O)c2nn3ccccc3c2Cl)n1 +CCC(C)N(Cc1ccccc1)C(=O)c1ccc2c(c1)OCO2 +COc1ccc(-c2nnc(SC(C)C(N)=O)o2)cc1 +O=S(=O)(NCC(O)Cc1ccccc1)c1ccc(F)c(F)c1 +CCCCNC(=O)C(C)Sc1nnc(-n2nc(C)cc2C)n1N +CN(C)C(=O)C1CCCN(Cc2cncs2)C1 +CCc1ccc(CNC(=O)c2ccc(C(=O)N(C)C)cc2)s1 +COCc1c(C(=O)OC(C)C(N)=O)oc2ccccc12 +CCn1nc(C(=O)Nc2cnn(C)c2)c(=O)c2cc(F)ccc21 +COc1ccc(C(=O)OCC(=O)Nc2cc(C)ccc2C)cc1OC +COC(=O)c1occc1CSc1nnc(N)n1C +CN(CC(=O)NC1CC1)c1ncnc2c1cnn2CCO +CCOC(=O)c1cnn2c(C(=O)OC)cc(-c3ccn(CC)n3)nc12 +COc1cc(C(=O)OC(C)C)cc(OC)c1OC +CC(=O)c1ccc(NC(=O)Cn2cnc3c(cnn3C)c2=O)cc1C +CN(Cc1c(F)cccc1Cl)C(=O)CNC(=O)C1CCCC1 +CC(Oc1ccc(F)cc1)C(=O)Nc1ccc(N2CCOCC2)nc1 +COCC(=O)NC(C(=O)Nc1cnn(-c2ccccc2)c1)C(C)C +Cc1nnc(SCc2ccccc2F)n1-c1ccccc1 +COc1ccccc1OCc1cc(C(=O)NCC(C)(C)C)n[nH]1 +O=C(c1cc(O)n[nH]1)N1CCc2c(nc(-c3ccccn3)[nH]c2=O)C1 +NC(=O)c1n[nH]c2ccc(NC(=O)C3C4CCCC43)cc12 +CCC(=O)N1CCCC1C1CCCN1c1ncnc2ccsc12 +COCC(O)c1cc(F)cc2c1NC(=O)C2(C)C +CCCCc1nn2c(CO)c(-c3ccccn3)nc2s1 +COc1c(C)cccc1C(=O)Nc1ccc(NC(C)=O)cc1 +COc1cccc(OC)c1-c1nn2c(-c3cc(C)n[nH]3)nnc2s1 +CN(C)C(=O)C1CCN(c2cc(C(F)(F)F)nc3ncnn23)CC1 +CCOc1ccc(C(=O)N2CCN(C(=O)c3ccoc3)CC2)cc1 +COc1cc(C(=O)NCc2ccco2)ccc1OC(C)=O +O=c1[nH]c(C2NCCc3c2ccc(F)c3O)c(F)c(=O)[nH]1 +Cc1cccc(OCc2nnc(SCc3nc(C)c(C)o3)o2)c1 +CC(C)C(=O)N1CCc2nc(NC(=O)C3CC3)sc2C1 +COC(C)(C)c1noc(-c2ccn(-c3ccccc3Cl)n2)n1 +CCc1c(C(=O)Nc2cccc3cn[nH]c23)cnn1-c1ccc(F)cc1 +COC(=O)c1ccc(C(=O)Nc2ccc(C)cc2OC)nc1 +CN(C)C(=O)CCNC(=O)N1CCCC1C1CCCC1 +CC(=O)N1CCc2cc(CNC(=O)c3ccc4c(c3)OCO4)ccc21 +O=C1NCCCC1Nc1nc(C2CC2)nc2sc3c(c12)CCCC3 +O=C1CN(C(=O)c2cc3cccc(Br)c3o2)CCN1 +CCc1c(C(=O)N(C)CC2CC2)cnn1-c1cccc(Cl)c1 +Cc1cc(C)n(Cc2cccc(NC(=O)CCc3cnn(C)c3)c2)n1 +N#Cc1ccc(-c2noc(Cc3ccc(Cl)cc3)n2)nc1 +Cc1cc(C)c(C(=O)Nc2ccc(F)cc2)c(=O)[nH]1 +CCN1C(=O)Cc2cc(NC(=O)CCSc3ccccc3)ccc21 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1cccc2ccccc12 +COc1ccc(NC(=O)c2sc3ncccc3c2N)cc1 +O=C(CN1CCOC1=O)N1CCCC(CCc2ccccc2F)C1 +Cc1ccc(-n2nnnc2NC(C)c2nc3ccccc3[nH]2)cc1 +Cc1noc(C)c1CC(=O)Nc1ccc(S(C)(=O)=O)cc1 +COC(=O)Nc1cccc(C(=O)Nc2cc(F)ccc2OC)c1 +NC(=O)C1CCN(C(=O)NCc2ccccc2-n2ccnc2)CC1 +Cc1cccc(C)c1NS(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +Cc1ccccc1Cn1cc(C(=O)NCC2CCCO2)nn1 +O=C(CSc1ncc(-c2ccccc2)nn1)c1ccccc1 +COCCNC(=O)C(C)NS(=O)(=O)c1ccc(Cl)cc1 +N#CC1(NC(=O)c2cn(-c3ccccc3)nn2)CCCCC1 +CSc1ccc(CN(C)C(=O)CN2CCCC(NC(C)=O)C2)cc1 +Cc1cc(C)n(-c2ccc(C(=O)NCC3CCOC(C)C3)cn2)n1 +COCCNc1nc2ccccc2n1Cc1ccccc1 +CCn1cc(CN(C)c2ccc(-n3nc(C)cc3C)nn2)cn1 +Cn1c(CN2CCN(c3cccc(Cl)c3)CC2)cc(=O)n(C)c1=O +O=C(NCc1cnn(-c2ccccc2)c1)NC(C1CC1)C1CC1 +Cn1c(SCCOc2cccc(C#N)c2)nnc1N1CCOCC1 +CC(NS(=O)(=O)c1cccc(Cl)c1)c1ccccn1 +CCS(=O)(=O)NC1CCC(NS(=O)(=O)CC)CC1 +CC(=O)Nc1ccc(C)c(NC(=O)N2CC(C)CC(C)C2)c1 +Cc1nn(C(=O)OC(C)(C)C)c2nc(F)ccc12 +Cc1cc(F)ccc1NC(=O)N(C)Cc1cnn(-c2ccccc2)c1 +O=c1ccnc(SCc2cc(F)ccc2F)[nH]1 +Cc1ccc2oc(=O)c3cnn(CC(=O)NCc4cccnc4)c3c2c1 +COC(=O)NCC(=O)Nc1ccccc1-c1nc2ccccc2s1 +Nc1cnc2[nH]c(C(Cl)(Cl)Cl)nc2c1 +COCC(c1ccccn1)N(C)C(=O)c1cnc(-c2ccccc2)nc1 +CCOc1ccccc1NC(=O)Cc1c(C)noc1C +COC(=O)Nc1ccccc1C(=O)NCc1ccc(Cl)cc1 +O=S(=O)(NCCc1ccc(-n2cccn2)cc1)N1CCCCCC1 +Cc1ccc(CNC(=O)Cc2nc(Cc3ccc(F)cc3)n[nH]2)cc1 +COc1ccccc1C(=O)CC1(O)C(=O)Nc2c(C)cc(C)cc21 +COc1cccc(NC(=O)NCc2cccnc2)c1 +CC(C)NC(=O)N(C)CCOc1ccccc1F +COc1ccc(Cl)cc1CNC(=O)N1CCOCC1C1CC1 +CC(C)OCCN1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 +CCc1nc2c(N)nc3c(c(=O)n(C)c(=O)n3C)c2o1 +COCc1ccc(C(=O)NCCc2c(F)cccc2F)o1 +Cc1[nH]c2ncnc(NC(=O)C3CC=CC3)c2c1C +O=C1CC(C2NCCc3cc(Cl)c(Cl)cc32)C1 +CC(C)(C)n1ncc(Br)c1C(=O)NC1CC1 +COC(=O)c1sccc1NC(=O)c1ccco1 +Cc1cc(C)cc(NC(=O)Nc2ccc(Cn3cncn3)cc2)c1 +O=C(NCc1ccc2c(c1)OCCCO2)c1cc2c([nH]c1=O)CCC2 +Cn1cc(C(=O)NCC#Cc2ccc(F)cc2)nn1 +CC(C)N1CC(c2nc(COc3ccccc3)no2)CC1=O +Cc1csc(NC(=O)CSc2nc3nc(C)cc(C)n3n2)n1 +Cc1ccc(NS(=O)(=O)c2cc(N)ccc2F)cc1 +CN(Cc1nc2c(cnn2C)c(=O)[nH]1)c1ccc2ccccc2c1 +CCC(=O)C1CCCN(c2nncc(-c3ccccc3C)n2)C1 +CCCC(=O)Nc1cccc(CNC(=O)Nc2cccnc2)c1 +Cc1nn(CC(=O)Nc2cn(C)nc2C(N)=O)cc1Br +COc1ccc2cc(NC(=O)c3scnc3C3CC3)ccc2n1 +Cc1ccccc1C1CC1C(=O)Nc1nc(C(N)=O)cs1 +CC(C#N)CNC(=O)Nc1cc(C(F)(F)F)ccc1N1CCCC1 +CC(C)N1CC(C(=O)NC(c2ccccc2)C(F)(F)F)CC1=O +CCC(=O)N1c2ccc(S(=O)(=O)NC3CCCC3)cc2CC1C +CC(NC(=O)CC1C=CCC1)c1nc2ccccc2[nH]1 +CCc1sc(C(=O)NCc2ccncc2)cc1Br +Cc1c(N)cccc1Cn1ccc(OCCc2cccs2)cc1=O +COc1cccc(CNC(=O)C2CCCN2C(=O)C(C)C)c1 +Nc1cccc2oc(=O)n(Cc3cccc4ccccc34)c12 +CC(C)c1nc(COC(=O)c2cc(Cl)c[nH]2)cs1 +Cc1nn(C)cc1S(=O)(=O)Nc1ccccc1 +CS(=O)(=O)N1CC(NC(=O)c2cnccn2)C2OCCCC21 +Cn1c(=O)n(C)c2cc(NS(=O)(=O)c3cccc(C#N)c3)ccc21 +O=C(c1ccc2c(c1)OCO2)N1CCCCC1c1nc2ccccc2[nH]1 +CCC(C)(C)NC(=O)C1CCCN(C(=O)c2ccc(Cl)cc2)C1 +CN(CCC(F)(F)F)S(=O)(=O)c1ccc2c(c1)CCC2 +Cc1cc(NC(=O)C2CCCN(c3ncnc4sccc34)C2)[nH]n1 +CCOc1cccc(NC(=O)CNC(=O)C(C)CC)c1 +CCC(=O)Nc1ccc(C(O)CCN2CCOCC2)cc1 +CCOc1ccccc1NC(=O)NCc1cccc(NC(C)=O)c1 +O=C(c1ccnc(C2CC2)n1)N1CCCC1c1noc(C2CC2)n1 +COCCN(Cc1ccccc1)C(=O)c1cnc2ccc(C)cn12 +CCC(C)N(CCOC)C(=O)Cn1cnc(N)n1 +COc1ccc(CN(C)C(=O)CCc2nc3ccccc3[nH]2)cc1F +CC(C)c1noc(CCC(=O)N2CCNC(=O)C2)n1 +COc1cccc(NCC(=O)NC2CCCCC2)c1 +CC(C)(C)n1nc2c(c1-n1cccc1)CN(C(=O)C1CCC1)C2 +CCc1nc(CNC(=O)NCCc2cnn(C)c2)cs1 +CNC(=O)c1ccc(=O)n(Cc2nnc(C3CC3)o2)c1 +Cc1cc(C)c2c(NC(=O)NC3CCCCC3)n[nH]c2n1 +CC(NC(=O)Nc1cccc2ccccc12)C(=O)N1CCCCC1 +COc1cc(CNC(=O)N2CCOCC2C2CC2)c2ccccc2n1 +Cc1nn(-c2ccccn2)c2c1C(=O)C(C)(C)CC2 +O=C(NCCN1CCOCC1)c1ncccc1Cl +Cc1noc(C2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)n1 +CCNC(=O)Cn1c(NCC)nc2c1c(=O)n(C)c(=O)n2C +CCOc1ccc(NC(=O)c2cnc3ccccn3c2=O)cc1Cl +COc1ccc(C2=CCN(C(=O)C3CC(=O)N(C4CC4)C3)CC2)cc1 +COc1ccc2c(c1)C(C#N)(N1CCCC1)CCCO2 +COCCN(C)C(=O)Cn1cnc2ccccc2c1=O +Cc1ccc2c(c1)c(=O)c(C(=O)Nc1c(C)nsc1C)nn2C +O=C(Cn1ccn(-c2cccc(F)c2)c(=O)c1=O)NCc1ccco1 +O=C(c1cc2cc(F)ccc2o1)N1CCC(Nc2cccnc2)CC1 +Cc1nc(C)c(C(=O)OCc2nc(N)c3c(C)c(C)sc3n2)s1 +COCCOC(=O)c1c(C)oc2ccc(O)cc12 +Fc1ccc2c(c1)CCN(Cc1noc(-c3ccccc3)n1)C2 +Cn1ncc(NCC2CCCCO2)c(Cl)c1=O +CC1CN(C)CCN1C(=O)c1ccc(-c2ccccn2)[nH]c1=O +O=S(=O)(N1CCN(CCO)CC1)N1CCc2ccccc2C1 +Cc1c(N)ccc2nnc(-c3ccc(F)c(F)c3)n12 +Cc1cc(C(=O)Nc2ccc(N(C)C)nc2)ccc1F +CCOc1ccc(NC(=O)C(C)Sc2nncn2N)cc1 +CCCn1nnnc1Cc1ccc(Br)cc1 +O=C(NCCc1cc2ccccc2[nH]1)C1CCOc2ccccc21 +CCOC(=O)N1CCN(C(=O)C(C)Cc2ccccc2)CC1 +COc1c(NC(=O)NC2CCCCCC2)c(C)nn1C +Cc1cccc(OC2CN(C(=O)CCn3cc(C)cn3)C2)c1 +O=C(NCc1cc(Br)ccc1F)NCC1CCOC1 +CC1C(c2ccc3ncccc3c2)CCc2nc(N)nn21 +Cc1nc(CNC(=O)c2ccc(F)cc2OC(F)F)n[nH]1 +CCOC(=O)c1oc2ccccc2c1CNC(=O)C1CCCC1 +O=C(NCc1cccs1)c1scc2c1OCO2 +O=C(NCC#Cc1cccc(C(F)(F)F)c1)C1CCCO1 +Cc1cc(C(=O)Nc2cccc(-c3nc4ccccc4[nH]3)c2)no1 +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)nc(C)n3C)cc1 +O=C1CC(C(=O)Nc2ccccc2NCc2ccc(Cl)cc2)CN1 +CC(O)c1cc(Cl)ccc1OCC1CCOCC1 +Cc1nn(-c2ccccc2)c(C)c1N1CCN(S(C)(=O)=O)CC1 +C=CCNC(=O)c1ccc(NC(=O)COc2ccccc2C#N)cc1 +COCc1cc(C)nc2sc(C(=O)Nc3ccccc3C)c(N)c12 +N#Cc1cc2c(=O)[nH]c(N3CCCC3)nc2nc1N +COC1CCN(C(=O)c2cccnc2)C1Cc1ccccc1 +CCOC(=O)C1=C(CNc2cccc(C)c2)NC(=O)NC1C +CCOc1ccc(C(=O)NCc2cn[nH]c2)cc1OCC +COc1ccc(-n2cccn2)c(-c2nnc3ccccn23)c1 +CC(C(=O)N1CCCC1c1ccc[nH]1)n1nnc(-c2ccccc2)n1 +CC(CC#N)N(C)C(=O)Nc1ccc(Oc2cccnc2)nc1 +Cn1cc(Br)cc1C(=O)Nc1ccccc1OC(F)F +CC1CN(C(=O)CNc2ccccc2Br)CC(C)O1 +CC(C(=O)Nc1ccccn1)n1c(=O)[nH]c2ccccc2c1=O +CC(CC(=O)N1CCOCC1C1CC1)c1cccc(F)c1 +Cc1ccc(S(=O)(=O)NCc2ncoc2C)cc1C(F)(F)F +CCCS(=O)(=O)NCC(=O)Nc1cccc(CC)c1 +CCn1nc(C)c(NC(=O)c2cc3c(Cl)cccc3n2C)c1C +CC(C)N1CCN(C(=O)c2cc3ccccc3n2C)CC1 +CCc1c(C)sc(NC(=O)c2c(Cl)cnn2C)c1C(N)=O +CCCCC(=O)N1CCCCC(NC(=O)c2cc(C)n(CC)c2C)C1 +O=C(CSc1nn(-c2ccccc2)c(=O)[nH]1)NC1CC1 +Cc1ccc(C(=O)OCc2cc(=O)n3nc(C4CC4)sc3n2)cc1 +C=C(C)CN(CC)C(=O)Nc1cc(COC)ncn1 +CNC(=O)COc1ccc(Cl)cc1S(=O)(=O)N1CCOCC1 +COCc1nnc(-n2nnc(CO)c2C2CCC2)s1 +O=C(C1CC1)N(c1ccccc1)S(=O)(=O)c1ccccc1 +NC(=O)N1CCCC(C(=O)N2CCC(OCc3ccccc3)CC2)C1 +COCCC(=O)NCc1ccc(-c2ncncc2C(=O)N(C)C)cc1 +CNC(=O)COc1ccc(-c2cccc(-n3cccn3)c2)cc1 +Cc1cc(CN(C)C(=O)c2c[nH]c3cccc(F)c23)no1 +CC(=O)NCCCNC(=O)N1CCCC1c1ccc2c(c1)OCCO2 +CC1=C(C(N)=O)C(c2cnn(C)c2C)n2ncnc2N1 +CCOC(=O)N1CCN(Cc2csc(NC(C)=O)n2)CC1 +CCN(CC)C(=O)CCNC(=O)C(C)(C)c1ccccc1F +O=C(CCOc1ccccc1F)Nc1ccc(N2CCCCC2)cn1 +O=C(Nc1cccc(C(=O)N2CCCC2c2ccccc2)c1)C1CC1 +CCOC(=O)Nc1ccc(NCc2cccc(C#N)c2)cc1 +COC(=O)CSc1nc2ncc(C(N)=O)cn2n1 +O=C1CC(O)Cc2sc(Cc3ccccc3)nc21 +CC(=O)c1csc(NC(=O)C(C)Oc2cccc(Cl)c2)n1 +COCCOc1ccccc1NC(=O)N(C)Cc1ccc(C)s1 +CC(C)(CNC(=O)Nc1ccc(F)cc1)C(N)=O +COCCCN1CC2(CCN(C(=O)Cc3cccnc3)CC2)CC1=O +O=C(C1CCC1)N1CCC(Oc2cccc(F)c2)CC1 +CCC(C)NC(=O)c1nc(C)n(-c2ccccc2Cl)n1 +C#Cc1cccc(N(CC)C(=O)CNC(=O)CNC(C)=O)c1 +CCCN(CCC)C(=O)C1CCCN(c2ncnc3onc(C)c23)C1 +CN(CC(=O)NCC(F)(F)F)S(=O)(=O)c1ccc(Cl)cc1 +CC(NC(=O)N1CCCC1c1ccsc1)c1ccccn1 +CC(O)CNC(=O)COc1ccc2ccccc2c1 +CC(=O)N1CCN(c2ccccc2NC(=O)c2ccccc2F)CC1 +CC(=O)NCC(=O)Nc1ccccc1N1CCCCCC1 +Cc1ccc(Nc2ncnc(NCCC(C)C)c2N)nc1 +Nc1ccc2c(c1)N(C(=O)c1c(F)cccc1F)CCS2 +Cn1cc(CNC(=O)N2CCC3CCCCC3C2)cn1 +Cc1ccc(C)c(CS(=O)(=O)N2CCC(c3cc(N)on3)CC2)c1 +CC(=O)NCCNC(=O)NCCOc1ccccc1C +Cc1cccc(C)c1NC(=O)c1ccc2nnc(C)n2c1 +N#Cc1ccccc1OCc1ccc(C(=O)NCCc2ccco2)o1 +O=C(NCC1(c2ccccc2)CC1)c1c[nH]c(=O)c(Cl)c1 +COc1cccc(CC(=O)NCc2nc(-c3ccc(F)cc3)n[nH]2)c1 +Cc1nc(CCCNc2ncc(Cl)cn2)n[nH]1 +Oc1ccccc1N1CCN(CC(O)c2ccc(Cl)cc2)CC1 +CCOC(=O)N1CCN(Cc2nnc(-c3ccco3)o2)CC1 +CN(C)C(=O)N1CCC2CN(S(C)(=O)=O)CCOC2C1 +CCOc1ccc(-c2[nH]c3nc4cc(N)ccc4n3c2C)cc1OC +Cc1cccn2cc(C(=O)NCC3CCCCC3)nc12 +CC(C)(C)c1cc(-c2nc(-c3ccc(C#N)cn3)no2)no1 +O=C(Nc1ccccc1NC(=O)N1CCCC1)c1cc[nH]n1 +Cc1ccc2[nH]nc(C(=O)Nc3ccc4oc(C)nc4c3)c2c1 +CC1CCc2nc(NC(=O)C3CC(=O)N(CC4CC4)C3)sc2C1 +Cc1cc(C(=O)N(C)C(C)c2cc3ccccc3[nH]2)cnc1C +Cc1ccnc2nc(C(=O)Nc3nc(C(C)(C)C)cs3)nn12 +Cc1sc(-c2ccco2)nc1C(=O)Nc1ccnn1CC(C)C +Cc1cc(NC(=O)NCCC(=O)Nc2ccccc2)c2ncccc2c1 +COCCCC(=O)Nc1cnn(Cc2ccccc2C)c1 +COc1ccc(C(=O)Nc2cc(-c3sccc3C)n[nH]2)nn1 +CCc1ccc(CN(C)S(=O)(=O)c2ccc(NC(C)=O)cc2)cc1 +CC(C)Oc1ccc(C(C)NC(=O)c2cnn[nH]2)cc1 +CC(C)Cc1ccc(-c2csc3nc(N)nn23)cc1 +COC(=O)C(C)N1C(=O)C(C(C)C)Oc2cccc(N)c21 +COCc1nc2n(n1)CC(NC(=O)Nc1cc(F)ccc1OC)CC2 +COc1ccccc1C(C)NC(=O)COC(=O)c1cccc(O)c1 +CC(=O)c1sc(CCN2CCOCC2)nc1C(C)C +Nc1c(Br)ccc2c(C(=O)NC3CC3)nccc12 +CCCNC(=O)COc1cc(C(=O)NCC)ccc1N +N#CCCN(CCN1CCOCC1)C(=O)C1Cc2ccccc2S1 +O=C(CNC(=O)CSc1ccccc1)NCC(F)(F)F +COc1ccc(S(=O)(=O)Nc2ccccc2C(=O)N(C)C)cc1C +CCCC(=O)N1CCCC(C(=O)Nc2ccc3c(c2)CC(=O)N3)C1 +CC(=O)NCCNS(=O)(=O)c1ccc(F)c(F)c1F +N#Cc1c(CCCNC(=O)CC2C=CCC2)nn(-c2ccccc2)c1N +Cc1ccc(-n2cc(-c3ccnc(N4CCCC4)n3)c(C)n2)cc1 +CN(Cc1ccc2c(c1)OCO2)C(=O)Nc1ccc2c(c1)COC2 +CCC(c1nc(C2CC2)nn1-c1ccc(C)c(C)c1)N1CCOCC1 +Cc1ccc(CNC(=O)c2ccc(Cn3ccccc3=O)o2)cc1 +CCOc1ccc(NC(=O)CC(NC(N)=O)c2cccs2)c(C)c1 +Cc1noc(CN2CCN(S(=O)(=O)N(C)CCC#N)CC2)n1 +O=C(CN1CCCS1(=O)=O)NC(c1ccccc1)c1ccccn1 +COc1cccc2c1C(c1cc(O)cc(O)c1)NCC2 +Cc1ccc(N)cc1NC(=O)Cn1cccnc1=O +Cn1cccc1C(=O)NCc1ccc(CN2CCCC2=O)cc1 +Cn1c(-c2ccccc2)nnc1C(C#N)C(=O)NCc1cccnc1 +Cn1c(=O)oc2c(Br)cc(Br)cc21 +CCCCn1nccc1NC(=O)c1ccc(-n2cccn2)cc1 +Cc1cccc(CNC(=O)c2ncoc2-c2cccs2)c1 +CC(C)C(NC(=O)c1ccco1)C(=O)Nc1cccc(Cl)c1 +COCCN(C)C(=O)Nc1cccc(OCC(F)(F)F)c1C +COc1ccc(NC(=O)C(C)Oc2ccccc2OC)cc1OC +CCCCn1nc(C(=O)Nc2cccc3cccnc23)ccc1=O +CC(=O)Oc1ccccc1C(=O)N1CCc2ccccc2C1 +CCc1c(C(=O)Nc2c(C)cccc2C)cnn1-c1ccccn1 +COc1ccc(CC(=O)OCC(=O)N2CCCC(C(N)=O)C2)cc1 +CCOC(=O)c1cnn2ccc(NC(=O)c3ccccn3)cc12 +CC(C)(C)C(=O)N1CCC(c2nc3ccccc3cc2N)CC1 +COc1ccc(OC)c(C(C)NCc2cncs2)c1 +CN1CCN(C(=O)NCCN2CCOCC2)Cc2ccccc21 +Cn1nc2c(cc1=O)CN(Cc1nnnn1C1CC1)CC2 +NC(=O)c1cc(-n2cnnc2)c(Cl)cc1Cl +COc1ccc(Nc2c3c(nc4nncn24)CCC3)cc1OC +CCc1noc(CN(C)C(=O)NCc2ccccc2OC(C)C)n1 +CCOC(=O)c1cc(C)nc2c1cnn2CC(C)C +CCc1nonc1NC(=O)C(C)Oc1ccccc1F +O=C(c1nccc2ccccc12)N1CCCC(c2n[nH]c(C3CC3)n2)C1 +COc1ccc(OCc2nc(C3CC3)c(CC#N)s2)cc1 +O=C(Nc1cnc(-c2ccc(F)cc2)nc1)C1CC1 +O=C(Nc1ccc(O)cc1)c1snnc1-c1ccccc1 +Cc1nnc(CN(C)C(=O)c2ccc3ccc(Cl)cc3n2)n1C +COC(=O)c1sc(NC(=O)c2cnn(C)c2N)nc1C +CC(=O)N(CCc1ccccc1)CC(=O)Oc1ccc(F)cc1 +C=CCN(Cc1ccc(C#N)cc1)C(=O)Cn1c(=O)oc2ccccc21 +Cc1cc(C)n(-c2cc(NCCNC(=O)CC(C)C)nc(C)n2)n1 +CNS(=O)(=O)c1ccc(C(=O)N2c3ccccc3CC2C)o1 +COc1ccccc1CC1NCCc2c(OC)cccc21 +COc1cccc(Cn2nc(-c3ccco3)oc2=O)c1 +c1csc(-c2noc(Cn3nnnc3C3CCCC3)n2)c1 +Cc1cc(Br)ccc1Oc1nnnn1C +CC(C)(C)OC(=O)Nc1cccc(CN2CCOCC2C2CC2)c1 +COc1ccc(C(=O)NCC(=O)Nc2cccc(F)c2)c(O)c1 +CCc1ccc2c(c1)SC1=NC(=O)C(C)(CO)CN12 +CC(C)(C)c1ccc(C(=O)Nc2c(F)cccc2F)c(N)n1 +CC1CCCN(C(=O)Nc2cc(-n3cccc3)ccc2F)C1 +COc1ccc2oc(C(=O)N(C)CC(=O)N(C)C)c(C)c2c1 +Cc1nn(C)c2ncc(C(=O)N3CCOC4CCCC43)cc12 +CCC(=O)N1CCN(C(=O)c2c[nH]nc2-c2cccc(Cl)c2)CC1 +O=C(Nc1ccc2c(c1)CCC2)c1c[nH]c2ccccc12 +c1cc(NCc2cncnc2)cc(-c2cnco2)c1 +O=C(NC(Cc1ccccc1)C(O)c1nccs1)C1CCCCC1 +O=C(c1ccc(F)cc1F)N1CCC(CO)CC1 +Cc1ccc(-c2csc3c(=O)[nH]c(C)nc23)c(C)c1 +Cc1n[nH]cc1NS(=O)(=O)c1ccc2c(c1)CC(=O)N2C +Cc1noc(C)c1CN(C)C(=O)CCOC(C)C +Cc1ccc(C(=O)NCc2nc(Cc3ccccc3)no2)c(=O)[nH]1 +CS(=O)(=O)c1ccc(C(=O)Cc2ccco2)o1 +CCc1nc(CC(=O)Nc2cccnc2OC)cs1 +CN(Cc1ccccc1)S(=O)(=O)N1CCC(O)(CO)CC1 +C#Cc1cccc(NC(=O)CNC(=O)CCc2ccccc2O)c1 +N#CCSc1nccn1-c1ccc2c(c1)OCCO2 +Cc1cc(Cc2nc(C3CC3)nn2-c2ccncc2C)on1 +O=C1NCCCn2cc(S(=O)(=O)NC3CCCCCC3)cc21 +COC(=O)N1CCC(NC(=O)C(C)Oc2cccc(Cl)c2)CC1 +Cc1ccc(N2CC(NS(=O)(=O)N(C)C)CC2=O)cc1C +COc1ncccc1CNC(=O)CCOC(C)C +COC(=O)c1c(C)[nH]c(-c2nc(NC3CCCC3)sc2C)c1C +CN(Cc1ccccc1)C(=O)c1cc(S(N)(=O)=O)ccc1F +CC(NC(=O)CCNC(=O)c1ccco1)c1ccccn1 +O=C(Nc1cccc2cccnc12)c1ccccc1O +O=C(Cn1c(=O)oc2ccccc21)NCC1(O)CCc2ccccc21 +CCC(CC)N(C)C(=O)c1cc(S(=O)(=O)NC2CC2)ccc1C +CC(C)(C)c1ncc2c(n1)CN(c1ncc(Cl)cc1F)C2 +Cc1cc(C)n(NC(=O)c2cc(Cl)ccc2O)c(=O)c1C#N +NC(=O)CNC(=O)c1cc(COc2cccc(C(F)(F)F)c2)[nH]n1 +CCCOc1ncnc(NC(C)c2ccccc2)c1N +O=C(NCc1cccc(O)c1)Nc1ccc(F)cc1F +CCCn1c(SCC(=O)C(C)(C)C)nnc1-c1ccncc1 +Cc1ccsc1CNc1nnnn1-c1ccccc1 +O=C(Cc1nc(COc2ccccc2)n[nH]1)NCc1ccccn1 +COC(=O)Nc1ccccc1C(=O)N(C)CCOc1cccc(F)c1 +CCOC(=O)N(C)c1ccc(NC(=O)NC(C)c2ccncc2)cc1 +CCOc1ccccc1CCC(=O)N1CCCC1C(=O)N(C)C +CCn1nc(C2CCCC2)nc1Cn1nc(C)c(C)cc1=O +Nc1cccc(NC(=O)CCSc2ccccn2)c1 +c1coc(-c2noc(CN3CCOC(c4nccs4)C3)n2)c1 +COc1ccc(C(=O)Nc2nc(-c3cccs3)cs2)nn1 +COC(=O)CCCC(=O)C(C#N)c1nc2ccccc2s1 +COC(=O)c1sccc1NCc1ccc(F)cc1 +COC(C(=O)Nc1ccc(F)cc1Cl)c1ccccc1 +NC(=O)N1CCC2(CC2C(=O)Nc2cccnc2)C1 +N#Cc1ccc(NC(=O)Cc2ccc(F)cc2)nc1 +COc1cc(CC(=O)OC(C)C(=O)Nc2cc(C)no2)ccc1C +Cc1ccc2c(NC(=O)c3ccccn3)ccnc2c1C +CC(=O)N(C)CC(=O)NCCNc1cnccn1 +N#Cc1cccc(NC(=O)CCCOCc2ccco2)c1 +Cc1cccc(CNC(=O)c2cc3occc3n2C)c1 +CC(NC(=O)Cn1c(=O)n(C)c2ccccc21)C1CCCCC1 +NC(=O)Cn1ccc(-c2cccc(-c3ccc(C(F)(F)F)cn3)c2)n1 +CCC(C)NC(=O)Cc1ccc2nc(NC(C)=O)sc2c1 +O=C(NCCc1ccc(Cl)cc1)c1cccc(Cn2cncn2)c1 +Cc1ccc(N2CCC(NCc3nnc4n3CCCC4)C2=O)cc1 +O=C(Nc1ccc2c(c1)OCO2)c1cnc2[nH]ccc2c1 +CCN(CCO)C(=O)Nc1cc(C(=O)NCC(F)(F)F)ccc1C +CCCC(C)NC(=O)C(C)N1CCN(c2ccccc2)CC1 +COC(=O)c1cccc(NC(=O)c2ccc(-n3cnnn3)cc2)c1 +C=C(C)CN1CCN(C(=O)c2cnc(SC)nc2)CC1 +O=C(CN1CCSc2ccccc21)NCc1ccccc1F +C=CCNC(=O)CN1C(=O)C(C)Oc2ccccc21 +CCN(CC)S(=O)(=O)c1ccc(NCc2ccccc2)cc1 +COc1ccc(CSc2nnc(C(C)(C)C)n2N)cc1 +CC(c1ccncc1)N(C)C(=O)NCc1cccs1 +CC(=O)c1sc(CNc2ccc(Cl)cc2)nc1C +CNC(=O)c1cccc(OC(=O)C2CCCN(C(=O)C(C)(C)C)C2)c1 +Nc1cc(Cl)ccc1NC(=O)COC1CCCCC1 +Cc1cc(C)n2nc(CN(C(=O)C(C)(C)C)c3ccccc3)nc2n1 +Cc1noc(COC(=O)c2cc(-c3ccco3)nc3ccccc23)n1 +Cc1ccc(C(=O)NCCC(=O)N2CCCc3ccccc32)cn1 +CC(=O)Nc1nc(C(=O)N(C)c2cc(C)cc(C)c2)cs1 +OCCn1ncc2c(NC(c3ccccc3)c3ccccc3)ncnc21 +Cc1ccc(N2CCC3OC(COCC4CCOCC4)CCC32)nn1 +C#Cc1cccc(NC(=O)CCc2cccs2)c1 +CCCN(CC(=O)OC)C(=O)Cc1ccc(Br)cc1 +COCCN1CCN(C(=O)Nc2ccc(C)c(C)c2)CC1=O +CCC(C)(C)NC(=O)c1cc(OC)c(OC)cc1N +COCCN1CC(C(=O)Nc2cccc(COC)c2)CC1=O +CC1CCCN(S(=O)(=O)NCc2ncn(C)n2)C1 +COC(=O)c1ccc(NC2CCN(C(=O)OC(C)(C)C)CC2)c(N)c1 +c1cnc(-n2ccnc2)c(CNCc2cccn2-c2nccs2)c1 +CCOc1ccc(CNC(=O)c2cn3cc(C)ccc3n2)cc1 +Cc1csc2ncc(C(=O)NCC(C)C)c(=O)n12 +Cc1nc2ccccc2n(CCC(=O)NCCCc2ccccc2)c1=O +CCc1n[nH]c(SCC(=O)Nc2ccc(NC(C)=O)cc2)n1 +COc1ccc(COC(=O)c2cnc(C3CCCO3)s2)cc1 +CSc1ccc(NCc2nsc(N(C)C)n2)cc1F +Nc1ccc2c(c1)N(CC(=O)NC1CCCC1)CCO2 +CCOc1ccc(CN2C(=O)C(=O)c3ccccc32)cc1OC +NC(=O)C1CCN(C(=O)c2cnn(-c3cccc(Cl)c3)c2)C1 +CC(CO)C(C)NC(=O)Nc1ccc(OCC(F)(F)F)nc1 +CC(C)CC(C)(NCc1cc(F)ccc1Br)C(N)=O +COC(=O)Cc1csc(NCc2ccccc2OC)n1 +Cc1cc(C(=O)Nc2cccc(S(=O)(=O)NC3CC3)c2)c(C)o1 +CC(c1ccccn1)N(C)C(=O)c1cn(CCC2CCCCC2)nn1 +CN(C(=O)c1cnn(-c2ccccc2)c1)C1(C#N)CCC1 +O=C(CCCNC(=O)C1CC1)OC1CCCc2ccccc21 +NC(=O)c1ncc(-c2ccc(C(F)(F)F)cc2)o1 +COc1ccc(-c2n[nH]c(SCC(=O)N3CCOCC3)n2)cc1 +CNC(=O)c1nnn(-c2ccc3c(c2)OCCO3)c1N +O=C(COc1cc(Cl)c(Cl)cc1Cl)Nc1ccncc1 +CCOC(=O)CCNC(=O)C1C2C(=O)Nc3ccccc3C(=O)C12C +Cc1ccc(S(=O)(=O)N(C)Cc2ccoc2C)c(Cl)c1 +COCCN1C(=O)C2CCC1CN(C(=O)c1cc(C(C)C)n[nH]1)C2 +COC(=O)N1CCCC(C(=O)Nc2ccccc2-c2noc(C)n2)C1 +CCn1c(=O)n(CC(=O)NCc2ccc(F)cc2)c2ccccc21 +CN(Cc1cccc2ccccc12)C(=O)CN1CCCCC1=O +c1ccc2[nH]c(-c3nc(C4CCOCC4)n[nH]3)cc2c1 +O=C(Nc1nc2ccccc2s1)C1CCCN1C(=O)c1ccco1 +CCOc1cc(F)ccc1NC(=O)NCc1ccoc1 +Cc1ccc(C(=O)Nc2c(C)ccc(N)c2C)cn1 +COCCc1ncc(C(=O)NCc2ccc(F)cc2)c(N)n1 +CC(C)c1ccc2c(c1)S(=O)(=O)N=C(NC1CCCC1)N2 +CN(Cc1ccccc1)c1ncnc2c1NC(=O)CN2 +Cc1nc2ccc(NC(=O)NCCOc3ccccc3)cc2o1 +Cc1nnc(NC(=O)C(C)Sc2ccccc2N)s1 +N#Cc1ccc(CCC(=O)Oc2cccc(F)c2)cc1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)NCc1ccoc1 +O=S(=O)(c1ccccc1)N1CC=C(c2c[nH]c3ccccc23)CC1 +CC(Sc1nnc(C2CC2)[nH]1)c1nc2ccccc2c(=O)[nH]1 +CCCCNC(=O)CSc1nc2ccccc2n2cnnc12 +CCn1c(-c2ccc(O)c(OC)c2)nc2ccccc21 +O=C(Nc1ccc2c(c1)COC2)c1ccc(Br)cn1 +O=C(Cc1nnc(-c2cccs2)o1)NC1CCCCCC1 +CCOC(=O)c1cnn2ccc(NC(=O)c3ccno3)cc12 +CCOc1ccc(NC(=O)N(C)CCC#N)cc1C +Cc1cccn2c(CN(CCC#N)CCC(F)(F)F)cnc12 +COc1ccc(C(=O)N(C)C)cc1NCC(=O)NC1CC1 +CN(C)c1ccc(C(=O)NCc2cnn(C)c2)cc1F +Cc1noc(C)c1CCC(=O)Nc1n[nH]c(-c2ccccn2)n1 +Cc1cc(O)ccc1NC(=O)CCC(=O)c1ccc(F)c(F)c1 +Cc1ccn2c(CN3CCN(c4ccc(C#N)cc4F)CC3)cnc2c1 +N#CCCC(C#N)CN1CCc2ccc(Cl)cc2C1 +CCc1cnccc1C(=O)N1CC(CO)OCC1C +O=C(NCC1CCCO1)C1CNc2ccccc2O1 +Nc1c(NCCc2ccccc2)ncnc1NC1CCCC1 +Cn1nc(C(=O)NC(COc2ccccc2F)C(C)(C)C)ccc1=O +O=C(c1ccc(Cl)cc1F)N(Cc1ccncc1)C1CC1 +Cc1cccc(C(C)C)c1NC(=O)Cn1c(=O)c(C)nc2ccccc21 +NC(=O)OCCNC(=O)C1CCCC(C(F)(F)F)C1 +C=CCn1c(NC2CCCCC2)cc(=O)n(C)c1=O +CCCc1cnc(C)nc1N1CCn2nc(C)cc2C1 +N#Cc1ccc(C(=O)N2CCNC(=O)C2c2ccccc2Cl)cc1 +Cn1cc(C(=O)NC2CC2)c(-c2ccc3c(c2)OCCCO3)n1 +COCc1cc(C)nc(SCC(N)=O)c1C#N +CCN(Cc1cccc(C)c1)C(=O)NCc1nnc2ccccn12 +Cc1nnc(CSc2nnc(C)n2-c2ccccc2C)o1 +Cc1n[nH]c(C(=O)N2CCCC2C(C)C)c1Br +COC(=O)C(C)(C)NC(=O)c1ccc(NC2CC2)nc1 +COc1ccc(NC(=O)CCc2nc(-c3ccccn3)no2)cc1 +CCc1ncc(C(=O)N2CCC(N3CCOC3=O)CC2)cn1 +O=C(NCc1ccco1)c1cc(-n2cccc2)ccc1Cl +Cc1cc2nc(-c3ccc(NC(=O)c4nc[nH]n4)cc3)oc2cc1C +O=C1CN(C(=O)c2ccc(Br)cc2Cl)CCN1 +COc1ccc(NC(=O)CCc2ccco2)c(C(=O)NC2CC2)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)C(C)(C)c1cccc(C#N)c1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)Oc2c(C)cccc2C)cc1 +CCc1ccc(NC(=O)Cc2c[nH]c3ncccc23)cc1 +Cn1c(CC(O)c2ccccc2)nc2ccccc21 +O=C(NCCc1ccccc1)c1nnc(Cc2cccc(F)c2)o1 +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1cccc2ncccc12 +O=C(CCc1nc(-c2ccco2)no1)Nc1nccs1 +CCCOc1ccc(Cl)cc1NC(=O)C(C)NC(N)=O +COCCOc1ncccc1C(=O)N(C)CCC#N +CC=CCOC(=O)CN(C)C1=NS(=O)(=O)c2ccccc21 +c1nc(-c2nc(-c3ccc4c(c3)OCO4)cs2)c[nH]1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)Nc1cc(C2CC2)n[nH]1 +CCC(C)N(C)c1ccc(N)c(OC(C)(C)C)n1 +O=C(NCc1cc(F)ccc1F)Nc1ccn(Cc2ccccn2)n1 +CCC(C)C(=O)CSc1nnc(C2CC2)s1 +Cc1cc(OC(F)F)c(C(=O)Oc2cc(C(N)=O)ccc2C)s1 +Cc1ccccc1COC(=O)c1cccc(NC(N)=O)c1 +O=C(CCNC(=O)c1cccc(-n2cccn2)n1)NC1CCCC1 +O=C(NCc1cccnc1)Nc1nnc(-c2ccccn2)s1 +Cc1ccc(NC(=O)CCc2cn(C)nc2C)cc1S(C)(=O)=O +COc1cc2c(cc1F)CCNC2Cc1cccc(O)c1 +COc1cc2c(cc1Br)N(C(C)=O)CC2 +COc1cc(CNC(=O)CN(C)C(=O)c2cccs2)ccn1 +CC(Sc1ncn[nH]1)C(=O)NCc1ccccc1Cl +CCCNC(=O)CNC(=O)c1cccc(OC(F)F)c1 +C=CCOc1ccc(C(=O)N(C)Cc2cccc(C#N)c2)cc1 +CC(=O)Nc1ccc(C)c(NCc2csc(C)n2)c1 +CCOC(=O)CCN(C)C(=O)Cc1cccc(N)c1 +CC(C)C(C)N(Cc1ccco1)C(=O)c1ccncc1Cl +CCN(CC)C(=O)C(C#N)CCOc1cc(C)cc(C)c1 +COC(=O)c1ccsc1NC(=O)c1cnc(-c2ccccc2)s1 +CC(=O)c1ccc(CNC(=O)c2cscn2)nc1C +CCN(C(=O)COc1ccc(C)cc1OC)C1CC1 +CCOc1ccc(Cl)c(C(=O)Nc2ccccn2)n1 +Cc1cnn(CCCNc2ncnc3c2cnn3-c2ncccn2)c1 +Cn1c(=O)c2c(=O)c3ccccc3oc2n(C)c1=O +Cc1ccc(SCc2nc(-c3ccncc3)no2)cc1 +COc1ccc(Cc2nc3ccccc3n2CCO)cc1 +CC(=O)c1c(F)cc(F)cc1OCc1csc(-c2ncccn2)n1 +Cc1nc(CNc2ccccc2SCC(F)(F)F)cs1 +Cc1ccc(-c2ccc(C(C)(C)O)c(=O)n2C)cc1C +CC(Oc1cccc(C#N)c1)C(=O)N(C)C1CCCCC1 +O=C(CSc1nnc[nH]1)Nc1cc(C(F)(F)F)ccc1Cl +Cc1ccc(N(C)C(=O)c2ncn(-c3ccccc3)n2)cc1 +O=C(CNC(=O)c1cncn1-c1ccccc1)NC1CC1 +COC(=O)c1ccc(CN(C)Cc2nccn2C(F)F)o1 +Cc1ccc2oc(=O)n(CCNC(=O)Nc3ccc(F)cc3)c2c1 +COc1ccc2cc(NC(=O)c3nn(C)c(C)c3Cl)cnc2c1 +CC(C)C(=O)Nc1ccc(OCC(=O)NCc2ccc(F)cc2)cc1 +COCC(C)n1c(SC(C)C(N)=O)nc2ccccc2c1=O +CCCOc1ccc(Br)cc1CCO +Nc1ccc(S(=O)(=O)c2ccc(Cl)cc2)nc1 +Cc1cc(C(=O)Nc2cccc(Cl)c2)c(C)n1C1CC1 +COc1ccc(-c2cc(C(F)(F)F)n3nc(N)nc3n2)cc1OC +CC(C)(C)C(=O)NCCCC(=O)C(C#N)c1nnc2n1CCCCC2 +O=C(c1ccccc1O)N1CCN(CC2CCCO2)CC1 +CC(C)NC(=O)C1CCN(c2cc(-c3ccccc3)ncn2)CC1 +COCc1ccccc1C(=O)NC(C)c1ccc2c(c1)NC(=O)CO2 +CN(C)c1cccc(C(=O)NCCNS(=O)(=O)c2ccccc2)c1 +CC(=O)N1CCC(NC(=O)Cc2nc3nc(C)cc(C)n3n2)CC1 +N#CC(NC(=O)CNC(=O)c1ccccc1)c1ccsc1 +CCOc1ccc(OCC)c(NCC(=O)N2CCOCC2)c1 +COCC(=O)NC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +COc1ccc(CNC(=O)NCC2CCOC2)cc1OC1CCCC1 +CC(C)c1ccccc1NC(=O)c1ccc(-c2cc[nH]n2)o1 +COC(=O)c1ccccc1OC(=O)Cn1nc(C)c(Cl)c1C +COc1ccccc1S(=O)(=O)Cc1ccccc1 +CSc1ccc(C(=O)N(C)C(C)c2ccc(F)cc2)cc1 +CCCC1CN(S(=O)(=O)N2CCC(C)(C)CC2)CC1NC(C)=O +Cc1ccc(C)c(C(=O)COC(=O)c2n[nH]c(=O)c3ccccc23)c1 +CC(C)(C)OC(=O)NCC(O)c1cccc(C(F)(F)F)c1 +COCCCNS(=O)(=O)c1cccc(N)c1C +Cc1nc(SC(C(N)=O)c2ccccc2)n(CC2CCCO2)c1C +CC(CNC(=O)CCSc1ccccn1)N1CCOCC1C +CNC(=O)C1CC2CN(C(=O)Cc3cccs3)CC2N1C(C)=O +CCN(CC)C(=O)CCC(=O)N1CCC(C(=O)N(C)C)CC1 +COc1ccccc1C(=O)N1CCN(S(=O)(=O)C2CC2)CC1 +C=C(C)COc1ccc(C(C)=O)cc1NC(=O)C1CCCO1 +CCc1nc(CCNC(=O)NCc2ccccn2)sc1C +O=C(NCc1ccoc1)Nc1ccc(OCC2CCCO2)cc1 +COC(CNC(=O)c1ccc(C)[nH]c1=O)c1ccccc1 +O=C(C1CCOCC1)N1CCC2OCCC2(COc2ccccn2)C1 +O=C(NCC1COC2(CCCCC2)O1)c1cc(-c2ccco2)on1 +CC(=O)NC1CCCN(C(=O)Cn2ccc(-c3ccco3)n2)C1 +C=C(C)CN(CC)C(=O)c1ccc(OCc2cccnc2)cc1 +Cc1cccc(-n2ccnc2SCC(O)CO)c1C +COc1ccc(OC)c(CC(=O)Nc2nc(C3CC3)cs2)c1 +CC(NC1CCc2ccccc21)C(=O)Nc1ccc(F)cc1F +CCCCS(=O)(=O)NCC(=O)Nc1ccncc1 +CC(=O)c1cccc(COC(=O)c2cnn(C)c2C)c1 +Cc1occc1-c1nnc(CCC(=O)N2CC(C)OC(C)C2)o1 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+CCC(CC)c1nnc(NC(=O)c2ccc3ccccc3n2)s1 +Cc1ccc(NC(=O)CNc2cccc(C(N)=O)c2)c(C)c1 +O=C(NCc1cccnc1)C1CN(C(=O)COc2ccccc2F)C1 +CC(C)(C)C(=O)NCC(=O)Nc1cccc(CO)c1 +CCC1CCCN(C(=O)c2cnc3sccn3c2=O)C1 +CCc1nc(C2CCCN(C(=O)C(C)(C)NS(C)(=O)=O)C2)no1 +CCCC(C)NC(=O)CCn1[nH]c(=O)c2ccccc2c1=O +CC(=O)OC(C#N)c1ccc(Br)cc1 +CCOc1ccc(C(=O)N2CCN(C3CCCC3O)CC2)cc1 +CC(=O)Nc1cccc(NC(=O)CNC(=O)c2ccco2)c1 +COC1CCCC1OC(=O)c1cc(F)cc(F)c1 +CC=Cc1ccc(OCC(=O)Nc2ncccc2C)c(OC)c1 +NC(=O)c1cccc(-c2cc(O)cc(Br)c2)c1 +Cc1nc2nc(N)nn2c(C)c1CC(=O)NC(C)C +Cc1ccc(C)c(-n2ccnc2SC(C)C(=O)N(C)CCC#N)c1 +COc1ccc(F)c(NC(=O)CCn2cnc3ccccc32)c1 +Cc1nnc2c3c4c(sc3ncn12)CC(C)CC4 +CN(C(=O)CSc1ncnc2ccsc12)C1CC1 +COc1ccc(F)cc1NC(=O)NCC(C)(C)c1ccncc1 +N#Cc1c(F)cccc1NCCOc1ccc2c(c1)OCO2 +Nc1cnc(CCOc2ccc3ncccc3c2)nc1 +Cc1nc(CN2CCN(c3ncnc4c3cnn4C)CC2)oc1C +CC(=O)Nc1ccc2c(c1)Cc1cc(N(C)C)ccc1-2 +Cc1cc(C(=O)N2CCN(C(=O)Nc3ccc(F)cc3)CC2)n(C)n1 +COc1ccc(OC)c(CCNC(=O)c2ccc(OC)c(F)c2)c1 +CC(C)CC(C)(NC(=O)Cc1cccc(F)c1F)C(N)=O +CCOC(=O)N1CCN(C(=O)c2cnc3ccccn3c2=O)CC1 +COC(=O)CCCc1csc(-c2ncccc2C)n1 +CC(C(=O)N1CCCC1)N1CCOC(c2ccc(F)c(F)c2)C1 +CC(=O)c1c(C)oc(N)c1-c1ccc2ccccc2n1 +Cn1ccsc1=NC(=O)c1cccc(OCC2CCCO2)c1 +Cc1nnc(SCCS(=O)(=O)c2ccccc2)n1N +N#Cc1ccc(C(=O)N2CCN(Cc3ccccc3)C(C#N)C2)nc1 +COc1ccc(NC(=O)c2cc(F)cc3[nH]cnc23)cc1OC +CC1CCC(C)(NC(=O)Cc2cccc(OCC#N)c2)CC1 +Cc1ccc(CNC(=O)NCc2ccco2)cc1F +NC(=O)C1CN(Cc2ccc(-c3ccccc3Cl)o2)CCO1 +CC(CCC(C)(C)C)NC(=O)Nc1nccs1 +CC(=O)NCc1ccc(C(=O)N2CCCC2Cc2ccccc2)cc1 +CC(C)CCNC(=O)c1cnc2sccn2c1=O +CC(C)(C)c1ccc(NC(=O)N2CCCC2CN2CCOCC2)nn1 +CN(C(=O)c1ccc(NC(=O)c2cccs2)cc1)C1(C#N)CCC1 +COc1cc(OC)c(C(N)C(=O)NC(C)C)cc1OC +Cc1ccc(OCc2nc(C)c(N)c(C)n2)c(C)c1 +CCNc1ccnc(N2CCOC(CCOC)C2)n1 +O=C(Nc1cncnc1N1CCCC1)c1ccc(-n2cnnc2)cc1 +COc1c(F)ccc(C(=O)N(C)Cc2nncn2C(C)C)c1F +COc1ccccc1CNC(=O)CN1CCN(c2ccccc2)C1=O +COc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1Cl +Cc1nnc(SCC(=O)c2ccc3c(c2)CC(=O)N3)n1C1CC1 +Cn1cc(CN2CCc3cccc(F)c3C2)c(-c2ccncc2)n1 +O=C(CN1C(=O)COc2ccccc21)Oc1cccc(Cl)c1 +CCOc1ccc(NS(=O)(=O)c2ccc3c(c2)CCC3)cc1CO +CCNc1nc2c(OCC)ccc(OC)c2s1 +O=C(CSc1nc2cccnc2[nH]1)Nc1cccc(F)c1 +COc1ccc(C(=O)OCC(=O)NCC(F)(F)F)cc1 +CCNC(=O)N1CCN(CCOc2ccccc2Cl)CC1 +CCn1cc2c(c1-c1ccccc1Cl)c(=O)n(C)c(=O)n2C +Cc1cc(C)cc(N2CC(C(=O)Nc3cccc(C)n3)CC2=O)c1 +CN1CCOc2ccc(S(=O)(=O)NC3CCCCC3)cc21 +Cc1ccc(NC(=O)NCC(C)(C)c2ccncc2)c(F)c1 +COc1ccc(CN(C)C(=O)COc2ccccn2)cc1OC +Cc1cc(C)c(C(=O)Nc2nccn(C)c2=O)c(C)c1 +O=C(CC1CC2CCC1C2)N1CCN(c2ncccn2)CC1 +CC(=O)N1CCC(NC(=O)N2CC(C)CC(C)C2)CC1 +CCN(Cc1ccco1)C(=O)NCc1ccc(F)cc1 +CCCCc1cc(NC(=O)C2CCN(C(=O)OC(C)(C)C)C2)[nH]n1 +Cc1nc(C(=O)N(C)Cc2ccc3c(c2)OCO3)c[nH]1 +Cc1ccccc1C(=O)OCc1cc2cccc(C)c2[nH]c1=O +CN(CC1CC1)C(=O)c1ccc2c(c1)NC(=O)CS2 +CNC(=O)NCC(=O)N(Cc1cccs1)Cc1cccs1 +Cc1cc(C(=O)N2CCN(CCO)CC2)sc1C +O=C(NCc1cccs1)N(CC(F)(F)F)C1CCOCC1 +OC(c1ccccc1)c1ccc2nc(C(F)(F)F)[nH]c2c1 +COc1cc(C)ccc1NC(=O)CCc1nc(C(C)C)no1 +CCn1cc(-c2nc(-c3ccc(C)cc3)no2)c(=O)c2cc(F)ccc21 +Cc1cc(O)c(-c2n[nH]cc2-c2nc(C)cs2)c(O)c1 +C=CCNC(=O)C(C)OC(=O)c1ccccc1SC +O=C(OCCn1c(=O)oc2ccccc21)c1ccccc1Cl +COC(=O)c1c(NC(=O)c2noc(C)c2C)sc2c1CCCC2 +CN(C)S(=O)(=O)N1CCN(c2ccc(Cl)cc2)CC1 +O=C1CN(C(=O)NCc2ccnc(-n3cccn3)c2)CCN1 +CN(C)c1ncccc1C(=O)Nc1cccc(Cl)c1 +N#Cc1ccc(S(=O)(=O)Nc2ccccc2C(N)=O)cc1 +CCc1nc2nnc3c(=O)n(-c4ccc(C(C)C)cc4)ccc3n2n1 +N#Cc1ccc(Sc2nc(-c3ccncc3)n[nH]2)nc1 +CC(=O)c1cnc(Cc2c(F)cccc2Cl)s1 +COc1ccccc1-c1noc(CNC(=O)C(C)(C)C)n1 +CCCc1nc(N(C)CCc2ccccn2)c2cnn(C)c2n1 +CN(Cc1ccc(Cl)cc1)C(=O)Cc1cn2ccsc2n1 +Cc1nn(-c2ccc(Cl)c(C(F)(F)F)c2)c2c1CNCC2 +CCOC(=O)Cn1nc(CO)cc1-c1ccc(F)cc1 +CCn1ccc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)n1 +O=C(c1ccc2[nH]cnc2c1)N1CCC(c2ccccc2)CC1 +Cc1cccc(C(=O)NCC(=O)Nc2ccc(F)c(F)c2F)c1 +COCC1CCCN(c2nc3nonc3nc2N2CCOCC2)C1 +CC(OC(=O)c1cccc(O)c1)c1nc2ccccc2c(=O)[nH]1 +Cc1ccc(-c2ccc(C(=O)NC(C)(C)C)c(N)n2)cc1 +c1ccc(Nc2nnc(-c3ccncc3)s2)cc1 +COCC(C)N1CCN(C(=O)CCn2ccccc2=O)CC1 +CCS(=O)(=O)N1CCCc2cc(NC(=O)C3CCCC3)ccc21 +COC(=O)c1cn(CC(=O)NC2CCCc3ccccc32)nn1 +CC(C)N(C)C(=O)c1ccc(CNC(=O)N(C)CC(F)F)cc1 +Cc1nnc(NC(=O)Cc2csc(Nc3ccc(F)cc3)n2)s1 +CCNC(=O)Cn1nnc(-c2cccc(OC)c2)n1 +O=S(=O)(CC1CCCCC1)NC1CCC(O)CC1 +C=CCn1c(SCC(N)=O)nc2sc3c(c2c1=O)CCC(C)C3 +CCn1ccc2ccc(NC(=O)NCCc3cnn(C)c3C)cc21 +CCc1ncnc2c1CCN(C(=O)c1ccoc1)CC2 +COc1ccc(CN(C(=O)c2ccccc2F)C2CC2)c(OC)c1 +CNC(=O)c1cc(NC(=O)CCSc2ccccn2)ccc1F +COc1cccc(-c2noc(C(=O)NC(C)(C)C)c2N)c1 +O=C(OCCOc1ccccc1)C1CCN(C(=O)C2CC2)CC1 +Cc1cc(C(=O)Nc2nn(-c3ccccc3Cl)cc2C)c(C)o1 +COC(=O)c1ncn(CCCOc2c(C)cccc2C)n1 +Cc1nc2ccc(C(=O)NC(C)C3CC3)cc2nc1C +COc1cn2c(cc1=O)C(=O)N(CCNC(=O)CC1CCCC1)CC2 +COc1ncccc1CNC(=O)NCc1ccnc(-n2cccn2)c1 +CCN(C(=O)C1CC2CCC1O2)c1ccc(F)c(F)c1 +CC(=O)Nc1ccc(CNC(=O)c2ccn(C)c(=O)c2)cc1 +O=C(COc1ccc(F)cc1)NCc1cscn1 +CCCc1noc(-c2ccc(=O)n(CC(=O)NC3CCCCC3)c2)n1 +COc1cc(C(=O)NCc2ccccc2C)ccc1OC(F)F +COc1ccc(NS(=O)(=O)Cc2ccccc2F)cc1 +O=C1CC2C(CCN2C(=O)c2ccc[nH]2)N1CC1CC1 +COc1ccccc1NC(=O)C1CN(C(=O)c2cccs2)C1 +NC(=O)N1CCCC(C(=O)Nc2ccc3c(c2)COC3)C1 +Cc1nnc(NC(=O)c2sc3cc(F)ccc3c2Cl)s1 +CCOc1ccccc1C(=O)NC(O)(C(=O)OC)C(F)(F)F +Cc1cccc(NC(=O)CSc2cccc(N)c2)c1C +CCC1COCCN1C(=O)c1cc(Br)cnc1NC +O=C(Cc1c[nH]c2ccc(F)cc12)NCC1CN2CCCCC2CO1 +CC(=O)NCc1ccc(C(O)COc2ccccc2)cc1 +COc1ccc(NC(C)=O)cc1NC(=O)C(C)Oc1cccnc1 +CCc1ccc2nc(NC(=O)c3cn4cccnc4n3)sc2c1 +COc1ccc(-c2noc(CSc3ncccn3)n2)cc1 +Cc1nc(C2(NS(=O)(=O)c3ccc(C)c(C)c3)CCCC2)no1 +CC(=O)N1CCC(C(=O)NCC2(c3ccccc3)CCC2)CC1 +CN(c1ccccc1C(N)=O)S(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1c(C(=O)NCCCO)oc2c(Cl)cccc12 +CC1CCCN(C(=O)CN(c2ccccc2)S(C)(=O)=O)C1 +COC(=O)C(CC(C)C)NC(=O)c1[nH]c(C)c(C(C)=O)c1C +CC(C)(C)OC(=O)CSc1nc(-c2cccs2)n[nH]1 +CC(=O)Nc1ccc(C)cc1NC(=O)CNC(=O)CC1CCCCC1 +CCCCOC(=O)Cn1cnc2c1c(=O)[nH]c(=O)n2C +CN(CC(=O)N1CCOc2ccc(F)cc21)C(=O)OC(C)(C)C +CC1=CCC2CN(C(=O)c3cccc4nccnc34)CC2C1 +Cc1cc2nnc(SCC(=O)c3ccc(F)cc3)n2c(C)n1 +CCCCc1nnc(NC(=O)NCc2ccnn2C)s1 +CN(CCc1ccccc1F)S(=O)(=O)c1cncc(Cl)c1 +CCC1(CNC(=O)NCC(C)c2nc(-c3ccccc3)no2)CC1 +C=CCNC(=O)c1ccccc1NC(=O)c1ccccc1Cl +CC(=O)NCCNC(=O)c1sccc1-c1ccccc1 +Cc1occc1CN(C)C(=O)CCOc1cccc(Cl)c1 +Clc1ccnc(NCc2ccc3[nH]ccc3c2)c1 +CC(Sc1nnc2n1CCCCC2)C(=O)NC1CCCC1 +CC1CCCC(CNC(=O)CNC(=O)Cc2cccc(F)c2)C1 +Cc1c(C(N)=O)sc2ncn(Cc3ccc(Cl)cc3)c(=O)c12 +CCc1cc(CN(C)C(=O)C2CC(=O)N(c3cccc(O)c3)C2)on1 +O=C(Nc1nc(CCCc2c[nH]c3ccccc23)n[nH]1)C1CC1 +Cn1c(-c2ccccc2)nnc1C(C#N)C(=O)CCc1cscn1 +Cc1ccc(C(=O)NCCc2cn3ccccc3n2)cn1 +CCCCC(COC)NC(=O)N1CCCC1CO +CC(C)CC(=O)N1CCN(Cc2cnc3ccccn23)CC1 +O=C1CCC(C(=O)Nc2ccc(C(=O)N3CCCCCC3)cc2)CN1 +CC(C)Oc1cccc(CNS(=O)(=O)Cc2ccccc2F)c1 +Cc1cc(C)cc(-n2c(=O)c3oc4ccccc4c3n(CC#N)c2=O)c1 +Cc1ccccc1OCCC(=O)N(C)CC(C)O +CC(C)CNC(=O)c1ccccc1NC(=O)c1ccc(F)cc1 +Cc1ccc(NC2=C(C(N)=O)S(=O)(=O)c3ccccc32)cc1C +CC(C)CCc1nnc(NCc2cccc3cnccc23)o1 +CC(=O)c1cc(F)ccc1OCc1nc(C)no1 +Cc1ccncc1NC(=O)NCCc1n[nH]c(-c2ccco2)n1 +COC(=O)CNC(=O)c1cc(Br)ccc1-n1cnnn1 +Cc1ccncc1NC(=O)NC1(c2ccc(Cl)cc2)CC1 +CCC12CN(C(C)=O)CC(CC)(CN(C(C)=O)C1)C2O +CCOCCSc1ccc(Br)cn1 +COCCS(=O)(=O)Nc1cnn(CC2CC2)c1 +O=C1CC(C2NCCc3cc4c(cc32)OCCO4)C1 +COc1ccc(N(CC(=O)N2CCCC2)S(C)(=O)=O)cc1Cl +Cc1ccc(S(=O)(=O)NCCC(O)C(C)(C)C)c(C)c1 +CN(Cc1ccccn1)C(=O)c1cnc(Cc2ccc(F)cc2)s1 +CC(C)Cn1cc(NCc2nc(-c3ccccc3)cs2)cn1 +c1ccc(-n2cccn2)c(CN2CCCC(c3nccs3)C2)c1 +Nc1cc(N)nc(SCC(=O)Nc2ccc(F)cc2Cl)n1 +CC(=O)NCC1CCN(C(=O)c2cnn(C)c2-n2cccc2)CC1 +CCC(C#N)Oc1cccc(CNC(=O)c2ccc3nncn3c2)c1 +O=C(NCCC(O)c1cccs1)C1COc2ccccc2O1 +CCCS(=O)(=O)N1CCCC(C(=O)NCC2CCCC(C)C2)C1 +COc1ccc(C(=O)N2CCc3c(Br)cccc3C2)nn1 +CCCCNC(=O)C1CCCN(C(=O)c2c(C)nn(C)c2C)C1 +COc1ccc(C(C)NC(=O)N(C)CCc2ccccn2)c(OC)c1 +CC(=O)NC(CC(C)C)C1NCCc2ccc(O)c(F)c21 +CC(C)NC(=O)Nc1ccc(C(=O)N2CCOC3CCCCC32)cc1 +Cc1nccn1Cc1ccc(NC(=O)Cc2ccc(F)cc2F)cc1 +COc1ccccc1N1CCN(c2ccc3nnc(C)n3n2)CC1 +CC(NC(=O)N1CCc2ccccc2C1CO)c1cccs1 +O=C(Nc1ccccc1)c1cc(Br)c[nH]1 +Cn1cc(S(=O)(=O)NCCOc2ccc3ccccc3c2)cn1 +COc1ccc(C(=O)Nc2c[nH]c(=O)[nH]c2=O)c(OC)c1 +COc1ccc(CN(C(=O)c2cccs2)C2CC2)c(OC)c1 +O=C(NC1=CC2N=CC=C2C=C1)c1csc(NCc2ccco2)n1 +CCCC(Nc1nccs1)Nc1nccs1 +COc1coc(C(=O)Nc2ccc(Br)cc2C)cc1=O +CC(C(=O)N1CCc2ccccc21)N1Cc2ccccc2C1=O +CS(=O)(=O)c1ccc(C(=O)c2ccccc2)cc1 +O=S(=O)(Nc1cccc2[nH]ncc12)c1ccc2c(c1)CCO2 +CS(=O)(=O)c1cc(S(=O)(=O)Oc2ccccc2F)ccc1F +CC(C)Cc1nc(NC(=O)CCc2ccc3c(c2)CCO3)n[nH]1 +COc1ccccc1CC(=O)N1CCCc2c(C(N)=O)cccc21 +Cn1cnc(CNC(=O)N(Cc2ccccc2)CC2CCCO2)n1 +CCc1ccc(C(NC(=O)NCc2ncn(C)n2)C(C)(C)C)o1 +O=C(NC(CN1CCOCC1)c1ccccc1)N1CCCC1 +Cc1cc(C)c(CNC(=O)N(C)Cc2cscn2)c(=O)[nH]1 +O=C(Cc1cn2ccsc2n1)NCc1nc(-c2ccccn2)no1 +CCC(=O)NC1CC(C(=O)OC)N(Cc2ccc(OC)c(C)c2C)C1 +CC(C)CN(C)C(=O)Nc1cc(Cl)ccc1N1CCOCC1 +Cc1ccc(S(=O)(=O)NCC(C)Cn2cccn2)cc1 +COC(=O)NCCOC(=O)c1ccc(-n2cc(C)cn2)cc1 +COc1ccc(-c2nc(CC#N)cs2)cc1OC +CCC(C)NS(=O)(=O)c1ccc(C(=O)N2CCOCC2)cc1 +Cc1oncc1C1NCCc2ccc(F)c(F)c21 +CC(C)(C)C1CCc2c(nnn2-c2cccc(N)c2)C1 +CCOc1nc(C)nc(NC2CCCCC2C)c1N +COCCCCC(=O)N1CCc2ccc(Br)cc21 +CCOc1ccccc1-n1nnc(C(=O)OC(C)C)c1N +CC(C)S(=O)(=O)c1ncc(CO)n1Cc1ccccc1 +CC(=O)NC(CC(=O)Nc1ccc(F)c(F)c1)c1ccccc1 +O=C(COc1ccccc1F)Nc1ccccc1OC(F)F +CC1Cc2cc(C(=O)CN3CC(C)OC(C)C3)ccc2N1 +Cc1cc(=O)n2nc(NCc3c[nH]nc3C)sc2n1 +CC(=O)Nc1ccc(C(=O)OCC(=O)Nc2cccc(C)c2)cc1 +COC(=O)CCCOc1ccc(Cl)cc1CO +COCCCN(C)S(=O)(=O)c1ccc(Br)cc1F +CC1(C)C(NC(=O)CN2C(=O)CCc3ccccc32)C2CCOC21 +Cc1cc(NC(=O)c2n[nH]c(=O)c3ccccc23)no1 +O=c1[nH]nc(CCn2ccnc2-c2ccncc2)[nH]1 +COc1ccccc1CNC(=O)CCC(=O)c1cccs1 +Cc1ccc(CN2c3ccccc3NCC2C)cc1N +Cc1ccc(C(=O)N2CCNC(=O)C2)cc1Cl +CC(C)C1Nc2ccccc2C(=O)N1CC(=O)NCc1ccccn1 +Cc1noc(C)c1CCC(=O)OCc1ccc2c(c1)OCO2 +Cc1cc(NC(=O)c2cc3cc(Br)ccc3o2)n(C)n1 +CCN(CC)C(=O)N1CCN(C2CCCN(C(C)C)C2=O)CC1 +O=S(=O)(CCOc1ccccc1)c1ccc(C(F)(F)F)cn1 +Cc1cccc(NCc2cc3cccc(C)c3[nH]c2=O)c1 +Cc1cc(C(=O)NCC(=O)NCCc2ccccc2Cl)n(C)n1 +Cc1noc(CCCC(=O)Nc2nc(C)c(SCC#N)s2)n1 +CC(C)c1nnc(C2CCN(C(=O)C3CC3)CC2)o1 +c1cncc(N2CCOCC3(CN(CC4CC4)CCO3)C2)c1 +COCCc1ccc(Oc2ccc(F)cc2N)cc1 +NC(=O)c1cc(Cl)cc(Cl)c1Br +CC(Sc1ccc(Cl)cc1)C(=O)N1CCCC1C(=O)N(C)C +COCCCN1CC2(CCCN(c3ncc(OC)cn3)C2)CCC1=O +CN1CC2(CCN(Cc3ccccc3C#N)C2)OC1=O +CCCc1[nH]nc(C(=O)NC(C)C(=O)OC)c1N +Cc1cc(NCCN2CC(C)OC(C)C2)n2ncnc2n1 +CC(=O)NCCNC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +Cc1ccc(C(=O)Nc2ccc(N(C)C)cn2)s1 +N#Cc1ccnc(N2CCN(S(=O)(=O)N3CCCCC3)CC2)c1 +CC(=O)Oc1cn(C2CC2)c2nc(C)n3c4ccccc4nc3c12 +COC(=O)c1ccc(NC(=O)NC2CCCC2)cc1 +CN(C)S(=O)(=O)c1cccc(C(=O)Nc2cccc(C#N)c2)c1 +CNc1ncc(Br)cc1C(=O)NCc1ccncc1 +COc1ccc(NC(=O)N2CCCC2c2c(C)noc2C)cc1OC +Cc1nn(C)c(C)c1CCC(=O)NCc1cc(-c2ccco2)on1 +CCC(C)Sc1nnc(-c2ccco2)n1CCC(N)=O +Cc1ccc(C(O)CNC(=O)c2ccc3c(c2)OCO3)cc1 +Cc1ccc(C2(O)CCN(Cc3[nH]cc(C)c(=O)c3C)CC2)nc1 +CCn1cc(S(=O)(=O)N(C)Cc2ccnn2CC)c(C)n1 +COCC(NC(=O)CCc1ccc(F)cc1F)C(N)=O +COc1ccc(C(CCO)c2ccc(F)cc2)cc1F +Cc1noc(C2CCCN2S(=O)(=O)N2CCOCC2)n1 +CS(=O)(=O)N1CCN(CCCOc2ccccc2)CC1 +N#Cc1ccccc1CN1CCN(C(=O)N2CCOCC2)CC1 +COc1c(C)cnc(CN2C(=O)c3ccccc3CS2(=O)=O)c1C +FC(F)CN(Cc1cnc(-c2ccccn2)s1)C1CC1 +c1ccc2c(c1)CC(CNc1ncnc3ccsc13)O2 +Cc1cc(C(=O)NCC(C)c2nc(-c3ccccc3)no2)[nH]n1 +CC1CCN(C(=O)c2c[nH]nc2-c2cccc(Cl)c2)CC1 +Cc1ccc(NC(=O)COc2ncnc3ccccc23)c(C)c1 +Nn1c(SCC(=O)NC2CCCCC2)nnc1-c1ccccc1 +COc1cccc(NC(=O)c2oc3c(c2C)C(O)CC(C)(C)C3)c1 +Cc1ccccc1C(=O)NCCOc1ccccc1 +Cn1ncc(Br)c1C(=O)c1ccccc1 +O=C(c1ccc(CCc2nc3ccccc3[nH]2)cc1)N1CCCCC1 +CCCCNC(=O)N1CCCC(c2nc(C(C)CC)no2)C1 +Nc1ccc(SCc2noc(C3CC3)n2)c(Cl)c1 +CNC(=O)Cn1cc(NCc2csnn2)cn1 +CC(=O)Nc1cc(S(=O)(=O)N(C)C)cc(C)c1C +CC(C)Cc1nc2cccnc2n1C1CCN(C(=O)NC(C)C)CC1 +C#CCOC(=O)c1nc(-c2ccccc2)n(-c2ccccc2)n1 +NC(=O)C1CCN(c2nc(-c3ccc(Cl)cc3)no2)C1 +CCOc1ccccc1-c1csc(NC(=O)c2ccoc2)n1 +CCc1noc(C)c1NC(=O)N1CCCC(C)C1CO +CCS(=O)(=O)NCCNC(=O)c1ccc(-c2ccc(F)cc2)o1 +Cc1ccsc1CNC(=O)NCc1cccc(C#N)c1 +O=C(Cc1cccs1)NCc1coc(-c2cccs2)n1 +CNC(=O)c1ccccc1NC(=O)Cc1ccc(OC(F)F)cc1 +O=C(Nc1ccc2nc(C3CCCO3)[nH]c2c1)c1ccc(Cl)cc1 +Cc1c(C(N)=O)c(-c2ccccc2)nn1-c1ccccc1 +COc1cc(C(C)=O)ccc1OC(=O)c1cnc(C)cn1 +Fc1cccc(-c2cnnc(NCc3n[nH]c4c3CCCCC4)n2)c1 +CCc1cccc(NC(=O)N2CCOCC2C2CC2)c1 +COc1ccc(-c2ccc(C#N)c(=O)n2C(C)C)cc1OC +Cc1nc(CN2CCCN(c3nc4ccccc4s3)CC2)no1 +CNc1ccc(C(=O)N(C)C(C)c2cccs2)nn1 +CN(Cc1ccc(Cl)cc1)C(=O)c1ccc(-n2ccnn2)cc1 +Clc1cccc(C(NCc2nnc(C3CC3)o2)c2ccccc2)c1 +Cn1cccc(NC(=O)c2ccccc2Oc2ccccc2)c1=O +CC(C)NC(=O)c1ccc(N(C)S(=O)(=O)c2cccs2)cc1 +CCC(C)Nc1nc(-c2scnc2C)cs1 +CNC(=O)c1ccc(NC(=O)CCCOc2ccccc2)cc1 +COC(=O)c1cnn(-c2cc(C)ccc2OC)c1N +Cc1cc(F)ccc1C(=O)Nc1cn(C)cc(Br)c1=O +Cc1nnsc1CN(C)C(=O)C1CC(=O)N(CC(C)C)C1 +Cc1ncsc1CN1CCC2(CC(NS(C)(=O)=O)CCO2)C1 +CC(O)(CNC(=O)c1ccc(C#N)cn1)c1ccccc1Cl +Nc1c(F)cccc1C(=O)Nc1ccc(Cl)cc1 +COCCN(Cc1ccc(F)cc1Cl)C(=O)Nc1cn[nH]c1 +CNC(=O)c1cc(C)ccc1NC(=O)c1ccncc1F +Cc1nccn1-c1ncccc1CNC(=O)CCN(C)c1ccccc1 +Cc1nc(CNC(=O)CCc2ccccc2OC(F)(F)F)cs1 +CCn1c(CN(C)CC2CCCO2)nc2cc(F)ccc21 +O=C(Cc1noc2ccccc12)Nc1ccc(-n2ccnc2)nc1 +Cc1ccccc1OCC(=O)N1CCCc2cc(N)ccc21 +CC(NC(N)=O)C(=O)Nc1ccc(Oc2ccc(F)cc2)nc1 +COC(=O)CNC(=O)Cc1cn(C)c2ccccc12 +O=C(CCn1c(=O)[nH]c2ccccc2c1=O)Nc1ccccc1 +CN(CCN1CCCC1=O)C(=O)COc1ccc(Cl)cc1 +O=C(NCc1cccc(CO)c1)NCC1CCCO1 +c1ccc(CNc2cc(-c3cnccn3)c3cc[nH]c3n2)nc1 +COc1ccc(C(=O)OCC(=O)N(C)C)c(OC)c1 +COc1ccc(NC(C)=O)c(NCc2ccn(-c3ccccc3)n2)c1 +CCc1cc(=O)[nH]c2nnc(SCC(=O)c3ccccc3)n12 +CCC(COC)NC(=O)c1scnc1C1CC1 +CCC(=O)N1CCc2c(C(=O)Nc3ccc(C)cc3)cccc21 +COc1ccc(CN(C)C(=O)COc2ccccc2O)cc1F +CCc1cc(-c2nc(-c3ccc(OC)nc3)no2)cc(=O)[nH]1 +O=S(=O)(Nc1cnn(C2CCOC2)c1)C1CCCCC1 +COc1cc(CNC(=O)NCc2cccnc2)c2ccccc2n1 +Cc1csc(NC(=O)NCCSc2ccccc2)n1 +COc1cccc(-c2nc3ccc(C)cn3c2C#N)c1 +O=C(NC1CCc2cc(Cl)ccc21)c1cccnc1 +O=C(Nc1ccc(N2CCNC2=O)cc1)OCC(F)(F)F +Cc1cnc(C(=O)NC(C)c2ccc3ccccc3c2)cn1 +Cn1nccc1C(=O)Nc1nnc(-c2ccc(Cl)cc2Cl)o1 +COC(=O)CSc1nc(C)cc(-c2cccs2)c1C#N +Cc1ccc(C)c(C(=O)N(C)CCOc2ccccc2)c1 +CCC(CC)c1nnc(NC(=O)c2ccncc2F)s1 +CC1(C)CN(C(=O)c2cncc(Br)c2)CCO1 +N#Cc1cccnc1N1CCN(C(=O)c2cccc3ncccc23)CC1 +COc1cc2c(cc1Cl)C(c1ccncc1)NCC2 +COc1ccc(-c2noc(C(=O)NC3CC3)c2N)cc1OC +COC(=O)c1ccc(Oc2c(OC)cccc2OC)c(N)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)CCc1nc(C)no1 +CC1(C)OCC2(CO1)CN(C(=O)c1cc(-c3ccco3)n[nH]1)C2 +COCCOc1ncccc1C(=O)N1CCCC1Cn1cc(C)cn1 +Cc1csc(C2CCCN(Cc3cc(C#N)cs3)C2)n1 +CC(=O)Nc1cc(C(=O)OCc2nc3ccccc3s2)ccc1C +COC(=O)C(C)CN(C)c1ncnc2cc(F)c(F)cc12 +COc1cccc(N(C)C(=O)c2ccccc2N)c1 +CCOCC1CCCN(S(=O)(=O)c2ccc(CC)s2)C1 +C#CCN1CCN(C(=O)NCC2CC=CCC2)CC1 +Cc1cc(C)cc(C(=O)N(CC2CCCO2)c2ccncc2)c1 +O=C(CSc1nncs1)N1CCc2ccccc21 +O=C(CSc1ncnc2nc[nH]c12)c1ccc(F)cc1 +Cc1cc(C)c(NC(=O)c2cc(OCC(F)F)ccn2)c(C)n1 +CNC(=O)C1CCC(NC(=O)N2CCOC(C)C2)CC1 +Cc1ccc2c(c1F)C(c1ccc(O)cc1)NCC2 +N#CC(C(=O)c1ccc(-c2cscn2)cc1)c1ccc(F)cn1 +CC(C)c1nnc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)s1 +CCCC(=O)N1CCC(Oc2nc3c(F)cc(F)cc3s2)CC1 +CC(=O)c1cccc(S(=O)(=O)NC2CCC(C)CC2)c1 +COc1ccc(CCCNC(=O)NCc2cccs2)cc1 +Cc1ccccc1C(C)(C)C(=O)N1CCC(O)CC1 +Cc1cccc(NC(=O)NCC(=O)N(C)Cc2ccc(C#N)cc2)c1 +CC(C)OCCC(=O)Nc1nc(-c2ccco2)cs1 +COc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(N)cc1C +COc1ccc(-c2cnn3c(=O)cc(C)[nH]c23)cc1 +CC(NC(N)=O)C(=O)NCc1ccccc1Cl +Cc1nc2ccccc2nc1N1CCN(Cc2ccccc2)CC1 +Cc1cnn(CCCNC(=O)C2CCCN(C(=O)N(C)C)C2)c1 +Oc1ccc(C2=CCN(c3ncnc4[nH]ncc34)CC2)cc1 +CC(C)CCn1c(SCC#N)nc2nccnc2c1=O +CCCCc1nnc(NC(=O)C2CCCN(C(=O)N(C)C)C2)s1 +CCC(C)n1cc(C(=O)NC)c(=O)c2c(N)cccc21 +CCc1nnc(CN2CC(c3ccc(OC)cc3)CC2C)o1 +COc1ncccc1NS(=O)(=O)c1ccc2c(c1)CCC2 +CCOC(=O)C1CCCN(C(=O)Nc2nc(C)c(C(C)=O)s2)C1 +COc1ccnc(NCCNC(=O)CC2CCCC2)n1 +Nn1c(SCc2ccc3ccccc3n2)nnc1-c1cccs1 +COC(=O)C1CCN(C(=O)c2coc(NC(=O)c3ccco3)n2)CC1 +O=C(N1CCCC1)C1(c2ccc(Cl)cc2)CCC1 +CC(=O)Nc1cccc(C(=O)Nc2nc3ccc(F)cc3s2)c1 +O=C(CSc1ncnc2nc[nH]c12)Nc1ccc(O)cc1 +Cc1cc(C)cc(C(=O)NCC(O)c2ccc3c(c2)CCO3)c1 +Cc1ccc(C(=O)CCC(=O)N2CCn3c2nc2ccccc23)cc1C +O=C(Nc1cccc(Cl)c1)Nc1nncs1 +O=C(CN1CCN(Cc2ccc(Cl)cc2)C1=O)NCc1ccco1 +CC1(C)Cc2nc3oc4c(=O)[nH]cnc4c3cc2CO1 +Cc1ccc(NC(=O)N(C)C)c(C(=O)N(C)Cc2ccccc2)c1 +COc1ccc(C)cc1CCNC(=O)CC1C=CCC1 +Cc1cccc(C)c1OCC(=O)N1CCN(C(C)C(N)=O)CC1 +N#CC(NCCCc1ccccc1)c1cccnc1 +CC(Sc1nncn1C(C)C)C(=O)c1c[nH]c2ccccc12 +Cc1cc(NC(=O)NC2CCCCC2)n(CCO)n1 +Cc1nnc(NC(=O)CC2CSc3nccc(=O)n32)s1 +CCC(=O)NCCc1csc(C2CCCN(C(=O)C(C)C)C2)n1 +CN1C(=O)C(C)(C(=O)N2CCCCCC2)Sc2ccccc21 +COC(=O)c1cc(NC(=O)c2ccccc2N)cc(C(=O)OC)c1 +FC(F)(F)c1nnc2sc(C3COc4ccccc4O3)nn12 +O=C(Cc1nc(-c2ccc3c(c2)CCC3)cs1)NCc1ccccc1 +Cc1ccccc1C(=O)Nc1cc(-n2cnnn2)ccc1Cl +Cn1ccnc1Sc1cc2c(cc1N)CCC(=O)N2 +CC(C)c1nc2c(n1C)CCN(Cc1nc3c(F)cccc3[nH]1)C2 +O=C(NCc1cccc(O)c1)C1COc2ccccc2O1 +O=C(NCCc1ccc(F)cc1)NC1CCC(O)CC1 +CCOc1ccccc1NC(=O)Cn1cnc2ccccc2c1=O +Cc1nc2cc(C(=O)N(C)Cc3nncn3C(C)C)ccc2[nH]1 +COc1cccc(CNC(=O)CNC(=O)C2CCC2)c1 +O=C(CCCNC(=O)c1ccc(F)cc1)Nc1nccs1 +O=C(NCCOc1ccc(Br)cc1)Nc1ccccn1 +Cn1nc(C2CC2)nc1C1CNc2ccccc2O1 +Cc1cc(C)n(Cc2ccc(C(=O)Nc3cc(F)ccc3F)o2)n1 +CCc1cc(NC(=O)NCCc2cccc(C(=O)OC)c2)n(C)n1 +CC(=O)c1cccc(NC(=O)c2nccc3c(N)cc(F)cc23)c1 +CNC(=O)C1CC2CCN(Cc3cccs3)CC2O1 +CS(=O)c1nncn1-c1cc(-c2ccccc2)nc2ncnn12 +Cc1cc(C)cc(CCNCc2c[nH]nc2-c2cccnc2)c1 +CSc1ccc(CN(C)C(=O)c2ccc(CNC(N)=O)cc2)cc1 +CC(C)CNC(=O)c1cn(C2CCN(c3nccs3)CC2)nn1 +CC1Oc2ccc(NC(=O)NCCc3ccc(F)cc3)cc2NC1=O +Cc1c(N)cccc1S(=O)(=O)N(C)Cc1cccs1 +Nc1ncn(CC(=O)Nc2c(Cl)cc(Cl)cc2Cl)n1 +Cc1cc(C(=O)N(C)Cc2ccco2)nc(N2CCOCC2)n1 +Cc1nnc(-c2cc3ccccc3n2Cc2ccccc2)o1 +CC(C)CN(CC(C)C)C(=O)c1cccc(CN2CCCC2=O)c1 +CCn1c(=O)c2ccccc2n2c(CSc3ccccc3)nnc12 +Cc1ccc(OCC#CCNC(=O)Cn2cccn2)cn1 +Cc1cnn(CC2CN(CC(O)c3ccc(C)c(C)c3)CCO2)c1 +CCCc1cc(C(=O)NCCN2CCOCC2)sc1C +CNC(=O)c1ccc(-c2cc(Cl)ccc2OC)nc1N +CC(Oc1ccccc1)C(=O)NC(Cc1ccccc1)C(=O)N(C)C +Cc1csc(N2CCN(CC(=O)Nc3ccnn3C(C)C)CC2)n1 +COc1cc(C)ccc1CNC(=O)c1ccc(OCC(F)F)nc1 +CCn1cc(C(=O)Nc2cc(C)ccc2C)c2cccnc21 +CCC(=O)N1CCCC1C(=O)c1ccc(F)c(F)c1 +COc1ccc(Br)c(CNCC(=O)Nc2ccccc2)c1 +Cc1cc(=O)n(C)cc1NC(=O)N1CCC(C)(c2ccccc2)CC1 +Cc1nc(OCCNC(=O)C2CC2)cc(N2CCOCC2)n1 +COc1ccc(CNC(=O)CSc2nnc(N)n2C)cc1 +CC1CCCN(C(=O)CSc2nc(-c3ccccc3)cn2N)C1 +O=C(NC1c2ccccc2CC1O)C1CC12CCOCC2 +CCC(C)NC(=O)CNC(=O)c1ccc(Cl)cc1 +CC(c1ccc(NC(=O)NCC(F)(F)F)cc1)N1CCOCC1 +COc1ccc(Cc2nc(-c3ccncc3)no2)cc1 +CC(NC(=O)C1CCN(C(=O)NC2CC2)CC1)c1ccccc1F +CC(C)CCNC(=O)Cn1ccn2nc(-c3ccccc3)cc2c1=O +COc1ccsc1C(=O)NC(C)c1cccc(N2CCCC2)c1 +N#Cc1nnn(-c2cccc(F)c2)c1C1CCCO1 +CCOC(=O)c1csc(NC(=O)C(C)Oc2ccccc2)n1 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1cc2ccccc2o1 +CNc1snnc1CN1CCOC2CCCCC21 +Cc1cc(=O)c(C2NCCc3c(O)ccc(F)c32)c[nH]1 +C=CCn1c(SCCC#N)nnc1-c1ccc(Cl)cc1 +Cc1ccc2ncc(CN3CCN(CC(F)(F)C(F)F)CC3)n2c1 +CC(OC(=O)CCC(=O)Nc1nccs1)c1cc(F)ccc1F +CCOC(=O)N1CCN(CC(=O)NCc2ccccc2Cl)CC1 +CN(C)c1ccc(C(N)=O)cc1NC(=O)COc1ccc(F)cc1F +COc1c(C(=O)NC2CCCC2)nnn1Cc1ccc(C)cc1 +COCc1ccc(C(=O)Nc2cc(OC)c(OC)cc2C)cc1 +CC(C)(C)CNC(=O)c1nc[nH]c1C(=O)NCC(C)(C)C +CCCc1nnsc1C(=O)Nc1ccc2c(CC)cc(=O)[nH]c2c1 +CCCNc1cc(N2CCC(CCC(=O)NC)CC2)ncn1 +CC(C)Cn1nccc1NC(=O)c1n[nH]c(=O)c2ccccc12 +c1cnc(-n2cc(NCc3cccc(-c4ccncc4)c3)cn2)nc1 +CCOc1cccc(C(=O)Nc2ccc(Cl)cn2)c1 +COC(=O)c1ccc(NCC2CCN(c3ccc(F)c(F)c3)C2)nn1 +CCC(C)Oc1ccc(C(=O)Nc2ccc(CC(=O)NC)cc2)cc1 +Cn1cnc2c(nnn2Cc2ccc(Cl)cc2)c1=O +O=C(c1c[nH]c(=O)cn1)N(Cc1ccc(F)cc1)CC1CCCO1 +CCN(CC)C(=O)c1ccc(NC(=O)Nc2ccccc2F)cc1 +COCCOCCNC(=O)c1cc(C)cc(F)c1 +COCc1ccc(CNC(=O)c2cccc(C)c2O)cc1 +Cc1nc(C(=O)OCCc2cnn(C)c2)cs1 +CC(C)C(NS(=O)(=O)c1cc(F)ccc1Cl)C(N)=O +CN(CCc1ccccn1)C(=O)c1c[nH]nc1-c1ccccc1 +Cc1nnsc1C(=O)Nc1nnc(Cc2ccccc2)o1 +CSc1ccc(OC(C)C(=O)Nc2cccc3[nH]cnc23)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cccc(-n2cccn2)n1 +Cn1cc(CNS(=O)(=O)c2ccc(Cl)cc2)cn1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)C1CCCCC1 +O=C(N=c1[nH]nc2ccccn12)C1(c2ccc(F)cc2)CCC1 +Cc1ccccc1OCCCN(C)C(=O)NCC(=O)N1CCCCC1 +CCN(Cc1cccc(F)c1)C(=O)Nc1nc(C)cs1 +Cc1ccc(Cl)cc1NC(=O)c1cc(S(N)(=O)=O)c(C)o1 +O=C(Nc1cc(-c2cccc(Cl)c2)nn1CCO)NC1CC1 +COCC(C)NS(=O)(=O)c1ccc(NC(=O)C2CC2)cc1 +c1ccc(CCc2n[nH]c(C(c3cccnc3)N3CCOCC3)n2)cc1 +O=C(CNS(=O)(=O)c1ccc(F)c(F)c1F)Nc1cccnc1 +COCC(C)N1CCN(C(=O)Cc2c(C)nn(C(F)F)c2C)CC1 +COc1cc(C(=O)Nc2cccc(C)c2)cc(Cl)c1OCC(N)=O +COc1cccc(NC(=O)c2[nH]c3c(c2C)C(=O)CCC3)c1 +O=C(NC1CCC1)C1CC2CN(C(=O)Nc3ccccc3)CC1O2 +O=C(NCCNC(=O)c1ccccc1-c1ccccc1)c1cccnc1 +CCOC(=O)c1cccc(NC(=O)c2cccnc2N2CCCC2)c1 +Cc1nc(COc2ccccc2Cl)[nH]c(=O)c1Cl +O=C1CCC(C(=O)N2CCN(C(=O)CN3CCOCC3)CC2)N1 +CCN(Cc1ccccc1NCC(=O)Nc1cc(C)on1)C(C)=O +CNC(=O)c1cccc(NC(=O)COC(=O)Cn2c(C)ccc2C)c1 +CC(=O)N1CCc2c(sc(NC(=O)c3cccc(F)c3)c2C#N)C1 +COc1ccc(C(=O)Nc2ccccc2C(=O)C(C)C)cc1OC +CC(C)(C)OC(=O)N1CCC2(CCC(=O)c3ccccc32)CC1 +Oc1ccc(-c2noc(-c3c(F)cccc3F)n2)cc1 +CCC(c1ccc(Br)cc1)n1nccc1N +Cc1ccc(NC(=O)C2CN(C(=O)c3cnccn3)C2)cc1 +Cc1ccc(-c2cc(C(=O)N(C)CC3(C)COC3)[nH]n2)cc1 +Cc1nn(-c2ccccc2)c(N2CCCCCC2)c1CO +CC(NC(N)=O)C(=O)NC(c1ccc(F)cc1)c1ccccc1Cl +CN(C(=O)Cc1ccc(F)cc1F)c1cccc(C#N)c1 +Cc1ccc(C(=O)CCC(=O)Nc2ccc3c(c2)NC(=O)CO3)s1 +CC(CC(=O)NCc1cccc(S(N)(=O)=O)c1)C1CCCCC1 +CCc1noc(C(C)N2CCN(CC(C)(O)c3ccccc3)CC2)n1 +Nc1cccnc1NCCNC(=O)CC1CCCCC1 +Cn1c(C2CC2)nc2cc(CCOC(=O)CN)ccc21 +O=C(COCc1cc(-c2ccco2)on1)NC1CCCCC1 +CN(Cc1ccncc1)C(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +CCOc1cc(NC(=O)COc2ccc(F)cc2)ccc1OC +COc1ccccc1CN(C)C(=O)COc1cccc(C(C)O)c1 +Cc1ccc(-n2nc(C)c(CO)c2C)cc1Br +COc1ccc(S(=O)(=O)Nc2cc(C#N)ccc2OC(C)C)cc1 +O=C(CN1c2cccc3cccc(c23)S1(=O)=O)Nc1ccccc1 +Cc1ccc(CNC(=O)C(C)Oc2ccccc2Br)o1 +COc1ccc2cc(CN3CCN4C(=O)NCC4C3)ccc2c1 +COC(=O)c1cc(-c2ccc(OC)c(C)c2C)[nH]c(=O)n1 +CCc1noc(CN2CCN(c3nnc(C)c(C)c3C(N)=O)CC2)n1 +COC(=O)c1ccc(S(=O)(=O)NCc2cc(C)no2)c(Cl)c1 +CCCCSc1ncc(CN2CCCC(C#N)C2)cn1 +N#Cc1ccc(CNC2(c3ccc(F)cc3)CCOCC2)cc1 +C=CCNc1nc(C(=O)OCc2ccc(C#N)cc2F)cs1 +CC(NC(=O)c1ccccc1)C(=O)N1CCCC1c1ccncc1 +Cc1noc(CCC(=O)NC(C)c2ccccc2)n1 +CC(=O)C1CCCN(C(=O)OCc2ccccc2)C1 +CCNC(=O)CSc1nnc(COc2ccccc2Cl)n1C +CN(Cc1ccccc1NC(=O)NC(C)(C)C)C(=O)OC(C)(C)C +CC(Sc1ncc(C#N)c(N)n1)C(=O)c1c(F)cc(F)cc1F +COc1cccc(-c2cc(CN(CC3CCCO3)C(C)=O)no2)c1 +CCc1cccc(C)c1NCc1ccc(O)cc1F +COc1cc(OC)c(NC(=O)CNC(=O)c2ccccc2)cc1F +CCCCN(C)C(=O)COc1ccc2ccc(=O)oc2c1 +CCc1ccc(CNC(=O)c2csc(C(=O)NC3CC3)n2)cc1 +c1ccc2c(c1)CC(c1nc(C3CCOCC3)n[nH]1)CO2 +N#Cc1ccc(F)c(CNC(=O)Nc2ccc3c(c2)NC(=O)CC3)c1 +CCOC(=O)c1cccc(NC2=NS(=O)(=O)c3ccccc32)c1 +Cc1ccc(C)c(NC(=O)CSc2nnc3ccc(N)cn23)c1 +CCC(=O)NC1CCN(C(=O)c2cccc(F)c2)C1 +CC(C)N(CC(N)=O)C(=O)CCSc1ccccc1 +Cc1nc(CN(C)C(=O)c2ccc3cc[nH]c3n2)cs1 +CC(C)NC(=O)CSc1nnnn1-c1ccc(Cl)cc1 +CCOc1ccc(CNc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1cccc2c1nc1n2C(CNC(=O)c2cnccn2)COC1 +CNc1nc(-c2c(C)cc(C)n(C3CC3)c2=O)cs1 +Cc1cccc(C2C(C(N)=O)=C(N)Oc3[nH]nc(C)c32)c1 +Cc1nc(C)c(CNCC(=O)NCCc2ccc(Cl)cc2)s1 +CN(C)c1ccc(C(=O)NC2CCN(C(=O)C(C)(C)C)CC2)cc1F +CN1CC(NC(=O)C2(c3ccc(F)cc3F)CCCC2)CCC1=O +CCn1cc(CNC(=O)c2cc(-c3cccs3)on2)c(C)n1 +CCCCOC(=O)C(C)n1c(C)ccc(C(C)=O)c1=O +CC(C)c1ccc(NC(=O)CCCn2cncn2)c(C(C)C)c1 +COC(=O)c1ccccc1Nc1ncnc(-n2ccnc2)c1N +O=C(Nc1nc(-c2ccc3c(c2)OCO3)cs1)c1cc[nH]n1 +Fc1ccc(-n2nnnc2SCc2ccccn2)cc1 +Cc1csc(N2CCCN(C(=O)C(C)NC(N)=O)CC2)n1 +CC1CN(C(=O)C2CCN(c3ncccn3)CC2)c2ccccc2O1 +CCC(Sc1ccccc1)C(=O)NCC(=O)Nc1cccnc1 +O=C1CCC(C(=O)NCCCc2ccc(Cl)c(Cl)c2)CN1 +CN(C)S(=O)(=O)c1ccc(CNS(C)(=O)=O)cc1 +CCCCn1nccc1NC(=O)c1cnc2ccc(C)cn12 +CCC(CO)(CO)NC(=O)c1nc(-c2cccc3[nH]ccc23)no1 +COC(=O)C(Cc1ccccc1)NC(=O)NC(C)C +CC(N(C)c1nc2ccccn2c1CO)C(C)(C)C +Cc1ccc(NC(=O)c2cccnc2)cc1Br +COC(=O)CCCN1CCOC(c2ccc(Cl)c(Cl)c2)C1 +CCCNC(=O)CNC(=O)N1CCCC(C(=O)NCC2CC2)C1 +Cc1cc(N2CC3CCC(C2)N(C)C3=O)nc(N)n1 +COCCn1cnnc1CN(C)C(=O)C1CC(=O)N(C(C)C)C1 +Cc1csc(=O)n1CCCC(=O)Nc1ccc(OCC#N)cc1 +Cc1ccsc1C(=O)Oc1cccc(C(=O)NC2CC2)c1 +COc1cccc(Cc2nc(-c3cn(-c4ccccc4)nn3)no2)c1 +CCNc1ncc(C(=O)NC(C)COCC)cc1Cl +CC1CC(=O)c2cnc(NC(=O)COc3ccc(Cl)cc3)nc2C1 +Cc1nc(SC(C)C(=O)N2CCN(c3ncccn3)CC2)oc1C +CCn1c(CNC(=O)c2cccnc2)nc2ccccc21 +COc1ccnc(NCc2ccc(CN3CCOCC3)cc2)n1 +Cc1cc(F)ccc1CCNC(=O)NCc1ncn(C)n1 +CC(C)CC(C)OC(=O)C1CCN(C(=O)N2CCOCC2)CC1 +CNC(=O)c1cc2c(nc1NC(C)C)CCN(S(C)(=O)=O)CC2 +Cc1n[nH]c(C)c1CCC(=O)Nc1ccc(Cl)c(C(=O)N(C)C)c1 +CCNC(=O)N1CC(C(=O)NC2CC2)CC(c2ccc(F)c(C)c2)C1 +O=C(N1CCCC1)N1CCN(S(=O)(=O)c2cccs2)CC1 +N#Cc1ccc(N2CCC(CNc3ncccc3C#N)C2)nc1 +Cc1cccnc1NC(=O)c1cc(N)cn1C1CC1 +Cc1cc(C(=O)NCc2ccc3c(c2)OCCO3)c(C)o1 +CCCCOC(C)C(=O)Nc1cc(F)ccc1OC +CC(=O)Nc1cccc(NC(=O)CCC(=O)c2ccc(C)cc2)c1C +Cc1ccc(C(=O)N2CCCCC2CNS(C)(=O)=O)cn1 +COc1ccccc1C(=O)Nc1cc(C)nn1CCO +CNS(=O)(=O)c1ccc(NC(=O)c2cc(C)cc(C)c2)cc1 +O=S(=O)(Cc1nc(C2CC2)no1)c1ccc(F)c(Cl)c1 +N#Cc1ccc(NC(=O)C2CCCN2C(=O)Cc2cccs2)cc1 +CCOC(=O)c1[nH]c(C)c(C(=O)N2CC(C)OC(C)C2)c1C +Cc1cccnc1NC(=O)c1cc(-c2ccco2)nn1-c1ccccc1 +COc1ccnc(N2CCN(C(=O)C(C)n3nc(C)cc3C)CC2)n1 +COc1nc(Nc2cccc(F)c2C#N)ccc1N +Cn1nc(CNC(=O)c2ccc(C(C)(C)C)cc2)cc1-c1ccccn1 +CCN(Cc1cccc(C)c1)C(=O)Nc1ccc(C(=O)NC)cc1 +O=C(CCC1CCCC1)NC1CC(O)C(CO)C1 +CCCn1cnc2c(-c3ccc(OC)cc3)csc2c1=O +O=C(c1ccncc1)N1CCC(CCOc2ccccc2F)CC1 +O=C(CCc1ccncc1)N(Cc1ccco1)c1ccccc1 +CCOc1cc(C)ccc1CNC(=O)NCC(C)(C)c1ccncc1 +CNC(=O)CC1CCCc2cc3c(cc21)OCCO3 +Cc1ccccc1C1CCCN(C(=O)Cc2c(C)nc(N)nc2C)C1 +COC(=O)C(CC(C)C)NS(=O)(=O)c1ccc(C)c(C)c1 +O=C(CSc1nnnn1C1CCCC1)N1CCCCC1 +Cc1nc(C(=O)OCc2coc(-c3ccccc3)n2)c2n1CCCC2 +CCN(Cc1ccc(F)cc1)C(=O)c1cc(-c2ccncc2)n[nH]1 +Cc1ccc(C(=O)N(CC2CCC2)C(C)c2ccccc2)c(=O)[nH]1 +Cc1nn(CCSc2ccc(F)cc2)c(=O)c(C#N)c1C +CN(CC(=O)Oc1ccccc1-c1ccccc1)S(C)(=O)=O +CC(C#N)CN(C)Cc1nnnn1-c1ccccc1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)OCC2CCCCO2)c1 +CC1(C)Oc2ccc(CO)cc2N(Cc2ccccc2)C1=O +Nc1cc(COc2ccc3ccccc3c2)nn1CCO +CNC(=O)CCCN(C)C(=O)C1COc2ccc(F)cc2C1 +O=C(c1ccc(OCc2noc(-c3ccoc3)n2)cc1)N1CCCC1 +COCc1cc(C(=O)NCC(=O)N2CCCC2)ccc1F +CCOC(=O)C1CCCN(c2ncnc3sc4c(c23)CCC4)C1 +CCCN1CN(c2nccs2)CN(c2nccs2)C1 +O=S1(=O)NCCN1c1ccc(Br)cc1 +CCCNC(=O)c1ccc(OCc2nnnn2C(C)C)cc1 +COCCN1CCN(C(=O)c2ccnc(-n3ccnc3)c2)CC1=O +Cn1c(=O)n(Cc2ccccc2)c(=O)c2c3c(sc21)CCC3 +CC(=O)c1cnc(NCc2ccccc2-n2ccnc2C)nc1C +Cn1ncc2c(=O)[nH]c(CN3CCCC3c3ccc(F)cc3)nc21 +COc1cc(CNC(=O)CSc2nc(C)cc(C)n2)ccc1C +CCC(O)(CC)CNC(=O)NCc1ccccc1 +Cc1cc(NC(=O)C(C)n2cccc2)c2ncccc2c1 +OCC1(COc2nc(Cc3ccc(F)cc3)no2)COC1 +Cc1nn(C)c(C)c1OC(=O)c1cnc(C2CCCO2)s1 +CN(Cc1cccc(O)c1)C(=O)c1cnn(-c2ccccc2F)c1 +CC(=O)Nc1ccc2ncn(Cc3cccc(C#N)c3)c(=O)c2c1 +NC(=O)c1ccccc1NC(=O)c1ncn(-c2ccccc2)n1 +COc1ccc(CNC(=O)N2CCc3sccc3C2)cc1 +Cc1cn(-c2ccccc2)nc1NC(=O)c1n[nH]c(=O)c2ccccc12 +O=C(NC1CCc2c(F)cccc21)c1cc(F)cc(F)c1 +CSc1cccc(C(=O)Nc2cc(C)nn2C(C)C)c1 +CN(C)c1nc(N)nc(CS(=O)(=O)c2ccc(F)c(F)c2)n1 +O=C(CC1COCC2CN(C(=O)c3ccncc3)CC12)NCC1CC1 +Cc1cc(C)n(-c2cccc(C3CC(=O)Nc4nc(N)ccc43)c2)n1 +OC(c1ccccc1)C1NCCc2cccc(F)c21 +Cn1cc(C(O)CNS(=O)(=O)c2cccs2)c2ccccc21 +CS(=O)(=O)N1CCCC(c2ccc(-n3ccnc3)cn2)C1 +Cc1n[nH]c(C)c1C(c1ccccc1)n1nnnc1N +CCOC(=O)c1sc2nc(C)c3c(c2c1N)CCCC3 +Cc1ccc(C)c(C(=O)NCc2ccc(NC(=O)C3CC3)cc2)c1 +CC(C)(C)C(=O)Nc1cccc(-c2nc(-c3ccc(C#N)cn3)no2)c1 +N#Cc1ccc(F)c(CSc2ccncc2N)c1 +NS(=O)(=O)c1ccc(C(=O)NCCc2ccccc2Cl)cc1 +COc1ccc(Br)cc1-n1nnnc1C +CN(Cc1ccc(C#N)cc1F)C1CS(=O)(=O)c2ccccc21 +CC1CCC(NC(=O)Cc2cccc(F)c2F)CC1 +CCc1noc(CC)c1CNC(=O)NCc1nnc2ccccn12 +CN(Cc1nc(-c2ccc(C#N)cn2)no1)C(=O)OC(C)(C)C +CN(C)S(=O)(=O)CC(O)(c1ccccc1)c1ccccc1 +CC(C)(C)OC(=O)N1CCC(CC(=O)N2CCOC(C)(C)C2)CC1 +COc1ccc(C2=Nc3ncnn3C(c3ccc(C)cc3)C2)cc1OC +CC(C)Cc1noc(CN2c3ccccc3C(C(N)=O)CC2C)n1 +Cc1ccc(NCc2ccccc2C(N)=O)cc1F +CC1COCC(C)N1C(=O)COc1ccc(Cl)c(Cl)c1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)C1CC2CCC1C2 +Cn1cc(NC(=O)Nc2cccc(NC(=O)c3cccs3)c2)cn1 +CCOc1nn(CC)cc1C(=O)Nc1cccc(C)c1C +Cc1ccc(NC(=O)Cn2cnc3ccccc3c2=O)cc1F +CC1CN(CC(=O)NC2(c3ccccc3)CCC2)CC(C)O1 +CC(=O)NC(C(=O)NCC1CCOC1)C1CCCC1 +CCCn1ccc(C(=O)NCc2ccc(F)cc2)n1 +COCc1cc(C(=O)N=c2[nH]c3ccccc3[nH]2)ccc1F +c1ccc(NC2C3CCOC3C23CCC3)c(CN2CCOCC2)c1 +Cc1cccc(C(=O)Nc2cc(C)nc3ccc(F)cc23)c1 +Cc1ccccc1CN(C)CC(O)c1ccc(F)cc1 +O=C(NCc1ccccc1)NC1CCCCc2ccccc21 +N#Cc1ccc(NCCNC(=O)c2cnccn2)nc1 +Cc1cccc(CC(=O)N2CCN(S(=O)(=O)C3CC3)CC2)c1 +O=C(NCC1(c2ccccc2)CC1)c1n[nH]c2ccccc12 +O=C(CCC(=O)c1cccs1)NCc1ccc(Cl)cc1 +Cc1cc(NC(=O)C(C)Sc2cccc(Cl)c2)on1 +O=C(CCOCc1ccccc1)Nc1nc(C2CC2)cs1 +C=CCNC(=O)Cn1nnc(-c2cccc(F)c2)n1 +O=C(NC1CCCCCC1)NC1CCN(C(=O)c2ccoc2)CC1 +CC(C)NC(=O)CSc1nc2ccccc2n2cnnc12 +Cc1cc(=O)n(CC(=O)Nc2cc(Cl)cc(Cl)c2)cn1 +NS(=O)(=O)N1CCC(C(=O)Nc2ccc(F)cc2)CC1 +Cc1cc(=O)cc(C2CCCN(C(=O)CC3CCCC3)C2)[nH]1 +CN(Cc1ccccn1)C(=O)CSc1nc2ccccc2o1 +CN(C(=O)CNC(=O)NC1CCCCC1)C1CC1 +CC(C)Cc1ccc(C(C)C(=O)NC2CCOC2=O)cc1 +Cc1nc(SCC(C#N)CCC#N)c2ccccc2n1 +COc1ccccc1OCCOc1ccc(-c2nnco2)cc1 +Cc1ccccc1OCC(C)NC(=O)N(C)Cc1nccs1 +O=C1CCN(C(=O)CCOCC(F)(F)F)CCN1 +Cc1cc(C)n(CC(=O)NCCc2ccc3c(c2)OCO3)n1 +N#Cc1ccc2ncc(CN3CCC(Nc4ccccc4)C3)n2c1 +Cc1cc2n(n1)CCC(=O)N2CC(=O)NCCCOC(C)C +COc1ccc(-n2nnnc2SCC(C)(C)O)cc1 +CCn1nc(C(=O)NCC(=O)NC(C)C)c(=O)c2cc(F)ccc21 +CC(=O)NCCNC(=O)N(CC1CCOC1)C1CC1 +CCc1ccc(C(=O)N(CC(C)C)CC(F)(F)F)o1 +COc1ccc(-c2cn[nH]c(=O)c2CC#N)cc1OC +Cc1cc(NCc2cncs2)ccc1C(=O)NC(C)C +COc1cccc2c1OCC(NCc1c(F)cccc1F)C2 +Cc1nc2ccc(NC(=O)NC3CCCc4sc(C)nc43)cc2[nH]1 +CN(C)C(=O)C1CCN(C(=O)CCc2ccc(C(C)(C)C)cc2)CC1 +[H]N=c1n(N)c2ccccc2n1CC(=O)c1ccc(Br)cc1 +CC(NC(=O)Nc1ccc(Cl)cc1)c1ccco1 +CC1CCN(c2ccc(Br)cn2)CC1 +COc1ccc(C(C#N)N2CCN(C(=O)c3ccccc3C)CC2)cc1 +CC(NC(=O)c1ccc(OC(F)F)cc1)C(=O)Nc1ccccc1 +Cc1cc(Oc2cncc3nnnn23)c(C)cc1N +Cc1ccc(C(=O)NCCS(N)(=O)=O)cc1Cl +COCCNC(=O)CNC(=O)Nc1cccc(N2CCCCC2)c1 +COC(=O)c1ccc(-n2ncc(C(=O)OC)c2N)cc1 +CC(CC(=O)NCC1CN2CCCCC2CO1)c1ccc(F)cc1 +OCC(Cc1ccc2c(c1)OCCO2)c1ccc(F)cc1 +COC(=O)CCN(C)S(=O)(=O)N1CCCCC1 +CCCOc1ccc(Cl)cc1NC(=O)Cn1ccccc1=O +c1ccc(CN2CCc3c(COCc4ccncc4)cncc3C2)nc1 +Cc1cnn(C2CCCN(C(=O)c3cc4nc(C)ccc4o3)C2)c1 +COc1ccc(C(=O)N(CCC#N)Cc2ccccc2)cc1 +Cc1cc(C(=O)Nc2c(C)nn(C)c2C)nc(N2CCOCC2)n1 +O=C(NCCN1CCOCC1)Nc1ccccc1SC1CCCC1 +Cc1ccc(C(CNC(=O)c2cccs2)OCCO)cc1 +Cc1cc(Cl)ccc1OCC(=O)NCCCN1CCOCC1 +COc1ccnc(NC(=O)c2cc(C)ccc2C)c1 +COc1ccc2c(c1)c(=O)c(C(=O)Nc1nc(C)cs1)cn2C +N#Cc1ccc(-c2noc(CCCS(=O)(=O)N3CCCC3)n2)nc1 +N#CC1(C(=O)N2CCCC(c3nccs3)C2)CCCC1 +Cc1c(C(=O)NC(C)Cc2cnccn2)oc2c(F)cccc12 +Cc1nc2ccc(NC(=O)NCc3ccc(C)c(F)c3)cc2o1 +COc1ccc2c(ccn2CCC(=O)NC2=CC3N=CC=C3C=C2)c1 +CCCn1nnnc1CSc1nnc(C=Cc2ccc(F)cc2)[nH]1 +Cc1[nH]ccc1C(=O)NC(C)c1cc(F)ccc1N1CCC(O)CC1 +Nc1nnc(COc2cccc(Br)c2)o1 +Cc1cc(C)n2nc(C(=O)N3CCN(C4CCCC4O)CC3)nc2n1 +Cn1ccc2cc(NCCc3nccs3)ccc21 +Cc1ccc(-c2csc3ncnc(NCCCO)c23)cc1C +Cc1cc(C(=O)Nc2cc(S(C)(=O)=O)ccc2F)c(C)o1 +COc1ccc(-c2cc(C(C)=O)c(C)o2)c(OC)c1 +Cc1cc(-c2nnc3ccc(Br)cn23)no1 +CCS(=O)(=O)N(C)C1CCN(C(=O)Cc2cccc(F)c2)CC1 +Cn1c(CN2CCOC(Cn3cncn3)C2)nc2ccccc21 +C#CCOC(=O)COc1ccc(Br)cc1 +COCC(C)NC(=O)NCc1ccc(-n2nc(C)cc2C)nc1 +Cc1cc2c(=O)n(Cc3cccc(OC(F)F)c3)cnc2s1 +NC(=O)C1CN(C(=O)CCCc2ccc(Cl)cc2)CCO1 +CCOc1cncc(N2CCC(c3nc(C(F)(F)F)c[nH]3)CC2)n1 +CCCCC(=O)NCc1ccnc(N2CCOCC2)n1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCN(CC(F)F)CC2)cc1 +CC(C)n1cc(C(=O)NCCc2ccccn2)c2ccccc21 +Nn1c(SCc2nnc(C(F)(F)F)o2)nnc1-c1ccccc1 +O=C1COc2c(cccc2C(=O)N2CCC(O)(C(F)(F)F)CC2)N1 +CC(C)c1cccc(OCC(=O)NCc2ccoc2)c1 +CC(C)OCC1OCCc2cn(CC3CCOCC3)nc21 +Cc1cc(C(=O)Cn2cnnc2C#N)c(C)n1CCc1cccs1 +CCS(=O)(=O)N1CCc2cc(C(=O)NCC(C)C)ccc21 +Nc1ccc(-c2nnc(-c3cccc(F)c3)o2)cc1 +CCN(C)c1ccc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1 +CN(CC(=O)NC(C)(C)C)C(=O)c1cc(-c2cccs2)on1 +COCc1ccccc1CNC(=O)Nc1ccc(C)cc1F +CCNc1ccc(C(=O)N(CC)CCOC)cn1 +O=C(NCCc1cn2ccccc2n1)NCCN1CCCCCC1=O +CC(=O)NCC(=O)Nc1cccc(-c2noc(C3CC3)n2)c1 +CC1CC1C(=O)NCC(Cc1ccccc1)NC(=O)C1CC1C +Cc1c(C(=O)NCc2cnn(C)c2)oc2ccc(Br)cc12 +C=CCCC(=O)N(C)S(=O)(=O)c1ccc(C(C)=O)cc1 +Fc1ccc(Nc2nn3c(nc4cc5c(cc43)OCCO5)[nH]2)c(F)c1 +CC1CN(CC(=O)N2CCNC(=O)C2)c2ccccc21 +Cc1cccc(C(=O)Nc2ccc(-c3cnco3)cc2)n1 +COCCNC(=O)CNC(=O)Nc1cc(F)ccc1F +CC(C)C(=O)NCCNC(=O)Cn1c(=O)cnc2ccccc21 +Cc1cccc(C)c1OCC(CC#N)N1CCCCC1 +Cc1oc2ncnc(NCc3cccc(-c4cnn(C)c4)c3)c2c1C +CC(C)CC(C(=O)NCc1cc(C(C)C)no1)N1CCCCC1=O +Cc1cc(CN(C)C(=O)c2cncc(Br)c2)no1 +CC(=O)Nc1cc(C(=O)Nc2ccc(Cl)cc2Cl)ccc1F +CCC(C(=O)N1CCN(CCOC)C(=O)C1)c1ccccc1 +CN(CC(=O)N1CCCC1)C(=O)c1ccc2c(c1)CCC2 +CC(C)C(C)NC(=O)CSc1nnnn1-c1cccc(F)c1 +N#CC(NC(=O)C1CC(=O)N(CC2CC2)C1)c1cccc(Cl)c1 +CN(C(=O)c1ccnc(N2CCCC2)c1)c1ccccc1 +CN(Cc1cccnc1)Cc1csc(-c2cccs2)n1 +CC(C)N(C)C(=O)c1cccc(S(=O)(=O)N2CCCCC2C)c1 +Cc1cccn2c(=O)nc(SCCC3OCCO3)nc12 +CC(=O)Nc1ccc(S(=O)(=O)Nc2cccc(Cl)c2C)cc1 +Cc1cc(C)c(C(=O)N2CC(=O)NC3CCCCC32)[nH]1 +O=C(Cn1ccc2ccc(Br)cc21)Nc1nncs1 +CC(=O)c1c(-c2cc(C)ccc2F)cnn(C)c1=O +Cc1occc1C(=O)Nc1nnc(COc2ccccc2)s1 +CN(C)C(=O)c1ccc(OC(=O)c2cn(C)nc2C(C)(C)C)cc1 +COc1cc(CNC(=O)N2CCc3cc(F)ccc3C2)ccn1 +O=C(CSc1nccn1C1CC1)NCc1ccco1 +CC(=O)c1ccc(NC(=O)COc2ccc3c(c2)OCO3)cc1 +CC(C)C(NC(=O)NCC(C)(O)c1ccsc1)c1ccccn1 +CC(C)N1CC2(CCCN(c3ccc(C#N)cn3)C2)CCC1=O +Cc1ccc(C)c(C(=O)CN2CC(C)OC(C)C2)c1 +CSc1ccc(C)c(C(=O)N(CCC(N)=O)Cc2ccccc2)c1 +Cc1cc(C)cc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c1 +O=C(Nc1cccc(-n2cncn2)c1)N1CCC(F)(F)CC1 +N#CCOc1cccc(CC(=O)Nc2cc3c(cc2Cl)OCO3)c1 +O=C1Nc2ccc(Br)cc2C12Nc1ccccc1S2 +COc1ccccc1CNC(=O)C(C)n1ncccc1=O +N#Cc1cn(C2CCC2)c2ncc(Br)cc12 +O=C1OC(C(=O)Oc2ccc3ccc(=O)oc3c2)Cc2ccccc21 +CN(CCc1ccccn1)C(=O)Nc1ccc(F)c(C#N)c1 +Cc1nnc(-n2nnc(CO)c2C(C)(C)C)s1 +CCC(=O)OCC(=O)c1cc2c(cc1F)NC(=O)CC2 +N#Cc1ccc(N(CCC(N)=O)Cc2ccccc2)nc1 +CN(C)c1ccc(C(=O)N(C)c2cnn(C)c2)cc1 +O=C(Nc1ccc2c(c1)OCCO2)c1cccc2[nH]ccc12 +O=C(NCC1=COCCO1)c1cc2c(F)cccc2[nH]1 +CCC(C)(C)NC(=O)CSc1n[nH]c(=O)n1Cc1ccccc1 +O=C(CNc1ccc(-n2nccn2)cc1)N1CCc2ccccc21 +Cc1ccc(NC(=O)CN(C)C(=O)Nc2ccccc2F)cc1 +Cc1cc(C(O)CNC(=O)c2cccs2)ccc1F +O=C(Cn1c(=O)[nH]c2ccccc21)Nc1ccc(Cl)cc1Cl +COCC(C)N1CCN(C(=O)c2cc(Br)cn2C)CC1 +Cc1nc(CCCNC(=O)c2cc(CC(C)C)no2)sc1C +CCN(CC(=O)NCC1CCCO1)S(=O)(=O)c1ccc(C)cc1 +O=C(NCc1cccc(Cl)c1)c1cc(-c2ccccc2)[nH]n1 +CC1CC1C(=O)Nc1cc(C(F)(F)F)ccc1N1CCOCC1 +COCc1ccc(C(=O)N2CCCCC2c2nc(C)cs2)cc1 +c1ccc(CN2CCN(COc3ccccc3)CC2)cc1 +Cc1cccc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)c1C +COCCN(C(=O)c1ccccc1O)C(C)COC +Cn1cc(C(=O)Nc2ccc(F)c(Cl)c2)nn1 +O=C(Cn1ncc(=O)c2ccccc21)Nc1cccc(Cl)c1Cl +COc1ccc(-c2nc3sc(C(C)C)nn3c2C#N)cc1 +C=CCNc1cc2n(c(=O)n1)CCc1cc(OC)c(OC)cc1-2 +O=C(NCCc1ccco1)c1cc2ccc3cccnc3c2[nH]1 +COCCCn1ccc(NC(=O)NC(C)c2ccccc2Cl)n1 +CCOc1ccc(NC(=O)NCc2cnn(-c3ccccc3)c2)cc1 +CC1CCN(C(=O)CN(C)S(=O)(=O)c2ccccc2)C(C)C1 +COc1ccc(NC(=O)c2cccc3cc[nH]c23)cc1 +COC1CCC(OC(=O)c2ccc(-c3nc(C)n[nH]3)cc2)CC1 +CC(=O)N1CCc2cc(Cl)cc(Br)c21 +NC(=O)COc1cccc(Cn2cc(-c3ccccc3)cn2)c1 +COc1cccc(OCCCNC(=O)c2ccc3cncn3c2)c1 +CN(C)S(=O)(=O)c1cccc(CN2CC(=O)Nc3ccccc32)c1 +CCCn1cc(C(=O)N2CCCC2c2nc(CC)no2)c(C)n1 +O=C(NCCc1cc2ccc(F)cc2[nH]c1=O)C1CC1 +COCCn1ccc2c(NC(=O)CCc3c(C)noc3C)cccc21 +CCOc1ncccc1C(=O)N1CCCC(CC)C1 +Cc1csc2c(=O)n3c(nc12)CCN(C(=O)c1ccnn1C)CC3 +CC(=O)c1c[nH]c(C(=O)N(Cc2ccccc2)Cc2ccco2)c1 +O=C(NCCn1ccnn1)Nc1ccc(OC2CCCC2)cc1 +CN(C)C(=O)c1ccc(C(=O)NC2CCCCC2)cc1 +CCCn1nc(NC(=O)COC)c2cc3ccc(C)cc3nc21 +CCC12CN3CCC1CC3C(c1ccnc3ccc(O)cc13)O2 +NC(=O)Cn1nccc1-c1ccc(F)c(Cl)c1 +CCOCC(=O)N1CCC(NS(C)(=O)=O)C1Cc1ccccc1 +Cc1ccc(S(=O)(=O)NCCS(=O)(=O)c2ccccc2)s1 +COCCOC1CCN(C(=O)Nc2cc(F)ccc2OC)CC1 +COc1ccc(CNC(=O)COc2ccc(F)cc2)cc1NC(C)=O +Cc1ccc(C2C3=C(COC3=O)Nc3[nH]nc(C)c32)cc1 +CC1CCCN(C(=O)c2cnc(N3CCOCC3)nc2N)C1 +CN(Cc1cnn(C)c1)C(=O)COc1ccc2c(c1)CCC(=O)N2 +O=C(CCC1OCCO1)c1cccc(C(F)(F)F)c1 +O=C(c1cccc2[nH]ccc12)N1CCOC2CCCCC21 +CC(=O)Nc1ccc(S(=O)(=O)C(C)C(=O)NCCC(C)C)cc1 +Cn1ncc2c(SCc3ccccc3OC(F)F)ncnc21 +Cc1cc(N)ccc1NC(=O)COC1CCCCC1 +Cc1cc(C)cc(NC(=O)CCc2c(C)nc3ncnn3c2O)c1 +CC(C)CNC(=O)c1ccccc1NC(=O)C(C)c1cccs1 +CCN(Cc1cccc(Cl)c1)C(=O)NCc1ncn(C)n1 +COc1ccc(-c2ncc(F)c(N(C)C)n2)cc1C +O=C(COC(=O)c1ccncc1)Nc1ccc2ccccc2c1 +COc1ccccc1CNC(=O)COc1cccc(CO)c1 +Cc1cc(C(=O)c2ccc3c(c2)CCO3)c(C)s1 +CC(=O)N1CCN(C(=O)c2sc3ccccc3c2C)CC1 +Fc1cccc(NCC2(c3ccc4c(c3)OCO4)CCOCC2)n1 +CN(C)c1ccccc1NC(=O)Nc1ccc2c(c1)CC(=O)N2 +CCN(CC(C)C(=O)OC)C(=O)c1c[nH]c2cccc(F)c12 +CC(C)CCC(C)NC(=O)NC1CCCCNC1=O +O=C1CCc2cc(OC(=O)CCC(=O)c3ccccc3)ccc2N1 +CSc1cccc(-c2ccc(C(=O)N(C)C)cc2)c1 +Cc1nn(Cc2ccccc2Cl)c2sc(C(=O)NCCO)cc12 +CCc1c(C)nc(N2CCN(c3ccccc3)CC2)[nH]c1=O +COc1ccc(OC)c(-c2csc(-c3cnccn3)n2)c1 +CNC(=O)c1ccc(NC(=O)c2cc3c(Cl)cccc3n2C)cc1 +COC(=O)C1CCN(C(=O)C2(c3cccs3)CCOCC2)CC1 +CSc1cccc(NC(=O)N(C)C(C)c2ccco2)c1 +CCS(=O)(=O)c1ccc(C(=O)NCCC(=O)OC)cc1 +O=C(NC(c1ccccc1)c1ccccc1)c1ccc[nH]1 +O=c1ccc(C(F)(F)F)nn1CCS(=O)(=O)c1ccccc1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)NC1CCCC(C)C1 +CC(=O)N1CCN(C(=O)C2(c3cc(-c4ccco4)on3)CC2)CC1 +O=C1OCCN1CCc1nc2c(s1)Cc1ccccc1-2 +CC1(C)Cc2cccc(OCC(=O)N3CCN(CCO)CC3)c2O1 +Cc1nnnn1-c1cccc(NC(=O)CSc2ccncc2)c1 +COc1ccccc1-n1c(N)c(C#N)c2c(c1=O)COC(C)(C)C2 +Cc1cc(NC(=O)c2cc(Sc3ncccn3)ccn2)no1 +CCC(CC)N(C)C(=O)Nc1ccc(C(N)=O)cc1 +CCCNC(=O)c1cn2ccnc(-c3ccc(C)cc3)c2n1 +Cc1ccc2nc(NC(=O)Cc3cccc(N)c3)sc2c1 +COCC(C)OC(=O)Cn1c(C2CC2)nc2c(N)cccc21 +Cc1nnc(SCC(=O)N2C(C)CCCC2C)s1 +COc1ccc(NC(=O)C2CCCCC2C(=O)N2CCCC2)cc1F +CN(C)C(=O)c1ccc(C(=O)Nc2ccc(Br)cc2)cc1 +COc1ccc(-c2n[nH]c(C)c2NC(=O)c2ccc(F)cc2F)cc1 +CCn1cc(NC(=O)N(C)CC2CCCC2)ccc1=O +O=C(COc1cccc2ccccc12)N1CCCC(O)C1 +COc1ccc(CNC(=O)c2ccc(=O)n(C)c2)cn1 +CCOC(=O)c1cnc2ccc(NC(=O)c3ccc(C)cc3)cc2c1N +COc1cc(NC(=O)C2CC2C)c(C(N)=O)cc1OC +CSc1ccc(C)c(-c2nc(-c3ccncc3)no2)c1 +CC(C)N(C(=O)c1cccc(OC(F)F)c1)C1CCOCC1 +Cc1noc(NC(=O)c2cccc(OCC(F)F)n2)n1 +NC(=O)c1ccc(Nc2cc(N)ccc2Cl)c(F)c1 +CC(C)OCCC(=O)N1CCN(C(=O)c2ccccc2F)CC1 +Cc1nc(C)c(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)s1 +CCOC1CCN(C(=O)c2cnn3c(C)cc(C)nc23)CC1 +CCCc1noc(N)c1-c1ccc(OC)cc1OC +Cc1nc2cc(C(=O)OCCNc3ncccn3)ccc2n1C +Cc1ccccc1C(O)CNC(=O)c1ccnnc1C +C=CCN1CC2(CCC1=O)CCN(C(=O)c1cc(C)cc(C)c1)CC2 +CC(=O)c1ccc(S(=O)(=O)N(C)C(=O)C2CCCC2)cc1 +Cc1ccc(F)cc1NC(=O)c1cccc(-n2cccn2)n1 +Cc1cccc(CC(=O)Nc2ccc3c(c2)CN(C(=O)C2CC2)CC3)c1 +O=C(CN1CCN(C(=O)C2CCCO2)CC1)N1CCCCC1 +COCC(=O)N(C)CC(=O)Nc1ccc(F)cc1-n1cccc1 +Cc1cccc(C(=O)NCCS(=O)(=O)c2ccccc2)c1O +COc1ccc(NC(=O)NC(C)C(=O)NCc2ccccc2)cc1F +COc1ccc(C=c2sc3nc(C)nn3c2=O)c(OC)c1 +O=C(CCc1ccco1)NCC(C1CCOC1)N1CCOCC1 +Cc1noc(C)c1C(=O)N1CCOC(c2ccc(Cl)cc2)C1 +CC(OCc1ccccc1)C(=O)NCc1cc(F)cc(F)c1 +O=C(CCn1ccc(=O)[nH]c1=O)N1CCc2ccccc21 +CCCNc1ccc(C(=O)N2CCCC(C)C2)nn1 +O=C(NC1CC1)C(c1ccccc1)N1CCOC(Cn2cncn2)C1 +O=C(NC1CC1)C1(c2ccc(Cl)cc2Cl)CCOCC1 +Cn1ccnc(NC(=O)c2cccc(SCC#N)c2)c1=O +Cc1nc(-c2ncccn2)sc1C(=O)NCc1ccnn1C +CCOC(=O)CN(C(=O)c1cc(C)cc(C)c1)C(C)C +Cc1nn(-c2ccccc2)c(C)c1CN(C)CCc1ccncc1 +O=C(CCn1cnnn1)Nc1ccc(Cl)c(Cl)c1 +COCCOCc1cccc(NC(=O)N2CCOC(C)C2)c1 +C#CCNC(=O)c1cc(-c2cc(C)sc2C)nc2onc(C)c12 +CCC1(O)CCN(c2cncc(C(=O)N3CCN(C)CC3)n2)CC1O +CC(CO)NC(=O)c1cnc(C2CCCO2)s1 +Cc1nc2ccc(C(=O)N3CCC(C)CC3)cc2s1 +COc1ccc(-c2cnc(N(C)C)c(C#N)c2)cc1F +O=C(CCn1cccn1)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(=O)Nc1ccc(S(=O)(=O)NCc2csc(C)n2)cc1 +O=C(NCc1cccc(F)c1)c1cnn2ncccc12 +CCN(CC)S(=O)(=O)NC(C)(C)CC(C)(C)C +C=C(C)CN(CC)C(=O)c1ccc(O)c(Cl)c1 +Cn1c(=O)n(C)c2cc(C(O)Cc3cccs3)ccc21 +O=C(OCC1CC(=O)N(C2CC2)C1)c1cnc2ccccn2c1=O +CCCCN1CC(C(=O)NCc2cccnc2)CC1=O +CCCN1CN(c2ccc(C)cc2)c2ncccc2S1(=O)=O +COCCCNC(=O)C(C)N1CCN(c2ncccc2C#N)CC1 +CC(C)C(=O)c1cccc(S(=O)(=O)NCC2CCCO2)c1 +O=S(=O)(Cc1ccc(-n2cccn2)cc1)c1ncccc1Cl +COC(C(=O)NC(C)c1nc(-c2cccnc2)n[nH]1)c1ccccc1 +Cc1c(C(=O)N(C)C)cnn1-c1ccc(Br)cc1 +CCCN(CC1CC1)C(=O)Nc1ccccc1N1CCCC1=O +CCOCCCNC(=O)c1cc(OC)c2c(c1)OCCO2 +Cc1cccc(CN2CCCn3cnc(CNS(C)(=O)=O)c3C2)n1 +CCOC(=O)N1CCN(CCC(=O)Nc2ccc(F)c(F)c2)CC1 +Cc1nn(Cc2csc(C3CC3)n2)c(C)c1CCO +Cc1ccc(C(=O)NCC(C2CCOC2)N2CCOCC2)o1 +O=C(c1cc(F)ccc1F)N1CCN2C(=O)C3CCCN3C(=O)C2C1 +O=C(c1cc(-c2ccccc2)[nH]n1)N1CCN(Cc2cccnc2)CC1 +COc1ccccc1-n1c(SCC#N)nnc1N1CCCCC1 +Nc1oc(-c2cccc(F)c2)cc1C(=O)c1ccncc1 +Cc1cc2nc(C(=O)NCc3snnc3C(C)C)cc(C)n2n1 +Cc1ccc(O)c(NC(=O)c2cccc(NC(=O)c3ccco3)c2)c1 +COc1ccc(CNC(=O)CCn2ncc3ccccc32)cc1OC +CCC(O)c1cnc2ccc(Br)cn12 +CN(C)c1ccc(C(=O)NCCCN2CCCC2=O)cc1 +CC(NC(=O)CCCOc1ccccc1)c1nc2ccccc2[nH]1 +CCN(CC(=O)N1CCCCC1)c1ccccc1C +NC(=O)COC(=O)c1cccnc1OCC(F)F +CNc1nnc(SC(C)C(=O)Nc2c(C)nn(C)c2C)s1 +O=C(NC1CCCCCC1)c1cnn2c(-c3ccco3)ccnc12 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cccc4cc[nH]c34)cc12 +Cc1nc2c(N)cccc2n1CC(=O)NCCc1ccccc1 +CCOCCC(=O)N(C)C1CCN(c2ccc(F)cc2)CC1 +CCCN(Cc1ccccc1)C(=O)Cn1c(=O)[nH]c2ccccc21 +Cc1nc(CCNC(=O)NC(C)Cc2c(C)nn(C)c2C)cs1 +Cc1cnc(C2NCCc3cc(Cl)cc(Cl)c32)cn1 +Cc1ccc(-n2nnc(-c3nnc(-c4ccco4)o3)c2C)cc1 +COc1ccc(-c2noc(COc3ccccc3C#N)n2)c(OC)c1 +CCc1cccc(C)c1NC(=O)Cn1nc2n(c1=O)CCCCC2 +Cc1ccc(NC(=O)NCC(O)c2ccoc2)cc1C +CN(C(=O)CNS(=O)(=O)c1cccs1)c1cccc(C#N)c1 +CCN(CC)c1ccc(C(=O)N2CCCC2c2cc(C)on2)cn1 +CC1Oc2cc(N)ccc2N(CCCOc2ccccc2)C1=O +Cc1nc(C)n(C2CCCN(C(=O)Cc3csc(C)n3)C2)n1 +C#Cc1ccc2cc3c(=O)n(C)c(=O)n(C)c3nc2c1 +CCCCc1nc(CN2CCOC(C)(C)C2)no1 +Cc1ccc(-n2cc(C(=O)Oc3ccc4cn[nH]c4c3)nn2)cc1 +O=C(CCOc1ccc(Cl)cc1Cl)Nc1c[nH]c(=O)[nH]c1=O +CC(=O)Nc1cc(C(=O)Nc2cccc(C)c2)nn1-c1ccccc1 +COC(=O)C(C)NC(=O)c1ccc(-c2ccccc2Cl)o1 +COC(=O)c1cnc(NC(=O)COc2cccc3ccccc23)s1 +Fc1ccc(OCc2noc(CN3CCOCC3C3CC3)n2)cc1 +O=C(C1CCCCCC1)N1CCCC(Cn2cc(CCCO)nn2)C1 +Cc1noc(C)c1CN1CCN(C(C)c2nc(C3CC3)no2)CC1 +Cc1ccnc(NCc2cccc(C(=O)N3CCCC3C(N)=O)c2)n1 +CC1CCC(C)(NC(=O)Nc2ccc(-n3cncn3)nc2)CC1 +Cc1csc(CNS(=O)(=O)c2ccc3c(c2)OCCCO3)n1 +CC(Oc1cccc(F)c1)C(=O)NCCOc1ccccc1 +Cc1nc(C(C)(C)NC(=O)Nc2ccc(F)cc2)sc1C +O=S(=O)(NCc1cccnc1-n1cccn1)c1cccs1 +COc1ccc(NS(=O)(=O)c2c(C)nn(C)c2C)cc1 +COc1ccc(F)c(NC(=O)CSc2ccccc2)c1 +CC(=O)Nc1ccccc1OCCC(=O)N(C)CCC#N +Cc1cc(C)n(CC2CCCN2C(=O)Cc2c(C)noc2C)n1 +CCOC(=O)c1sc(NC(=O)c2ccco2)c(C#N)c1C +COc1ccc(CNS(=O)(=O)c2cc3n(c2)CCN(C)C3=O)cc1 +O=C(Nc1ccc(Cl)cn1)c1cc(Cl)c2c(c1)OCCO2 +Cc1nc(CC(=O)Nc2ccc(Cl)cc2)sc1C(=O)NC1CC1 +CC(NC(=O)c1cccs1)C(=O)Nc1cccc(CO)c1 +CCC(CC)(CO)Nc1c(N)n(C)c(=O)[nH]c1=O +CC(C)COC(=O)N1CCCC1C(=O)Nc1ccccc1 +CCNC(=O)c1nn(-c2ccc(F)cc2)c(OCC)cc1=O +CCNc1nc(C2CCCO2)nc(OCCOC)c1N +Cc1cnc(CNc2ncc(C)c(-c3cnn(C)c3)n2)cn1 +COc1ccc(C(=O)Nc2cc(C)nn2-c2ccccc2)cc1OC +COc1ccnc(NC(=O)CCCc2ccc3c(c2)CC(=O)N3)c1 +COc1c(Br)cccc1CCNC(=O)c1cccn1C +Cc1nn(CC(=O)N2C(C)CCCC2C)c(=O)c2cc3occc3n12 +Cn1nncc1CN1CCCC(C(=O)c2ccc(F)cc2)C1 +COc1ccc(OC)c(CNC(=O)c2cnc(N3CCCC3)nc2)c1 +Cc1cc(NC(=O)c2ccc(-n3ccnc3)cc2)[nH]n1 +Cn1nnnc1COc1cccc(C(=O)N2CCCCC2)c1 +Cc1ccc(=O)n(Cc2ncnn2CCc2ccccc2)n1 +CCn1nc(C(=O)Nc2nc3c(s2)CCC3)cc1C +CCCC(=O)NCc1cccnc1N1CCNC(=O)C1 +Cc1ccc(C)n1-c1c(C(=O)NCC#Cc2ccccc2)cnn1C +COC(=O)c1ccc(NC(=O)C(C)n2nc(C)ccc2=O)cc1 +CCCCn1nnnc1NCc1cccc(Cl)c1 +NC(=O)c1cc(Br)cn(-c2ccccc2)c1=O +COCCNc1nnc(SC(C)c2c(F)cccc2F)s1 +CCCCn1nc(C(=O)N2CCCCCC2)ccc1=O +CCCn1cc(NC(=O)c2ccccc2Cl)ccc1=O +COCCn1ccc2c(C(=O)Nc3ccccn3)cccc21 +CCn1cc(NC(=O)c2ccc(Cl)cc2Cl)c(C(N)=O)n1 +CCOC(=O)C1CCCN(c2nc(CC)nc3c2cnn3C)C1 +Cc1cccnc1NC(=O)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +Cn1cnnc1Sc1ccccc1NC(=O)c1ccc(Cl)cc1 +Cc1cc(C)c(C2=NCCNC(C(F)(F)F)=C2)c(=O)[nH]1 +N#Cc1cccc(Oc2ccc(NC(=O)N3CCCC(O)C3)cc2)c1 +CC(NC(=O)c1cc(F)c(F)cc1Cl)c1ccco1 +Cc1ccc(-n2ncc3c(C)nnc(SCC(N)=O)c32)cc1 +CCCc1n[nH]cc1C(=O)N1CCCC(O)(CO)C1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)c1ccc(S(N)(=O)=O)o1 +CC(NC(=O)Cc1cccc(OC(F)F)c1)C(=O)N1CCOCC1 +CCN1CC(C(=O)Nc2cccc(OCC(F)(F)F)c2)CC1=O +C=CCCC1NCCc2ccc(C(F)(F)F)cc21 +O=C(CCC1CCCC1)N1CCc2[nH]nc(C(=O)N3CCCC3)c2C1 +Cn1ncc(NC2CC=CC2)c(Br)c1=O +CSc1ncccc1C(=O)OCc1nc(-c2ccccc2)no1 +CC(=O)NC(C)C(=O)Nc1ccc(Sc2nc(C)cs2)cc1 +O=C(NCC1CN2CCCC2CO1)c1cccc(F)c1 +CCOc1ccc(OC(=O)C2CCN(CC(F)(F)F)CC2)cc1 +CCCOc1ccc(Cc2ncc(C)s2)cc1N +O=C(c1nnc2sc(-c3ccccc3)nn12)N1CCCCC1 +Cc1ccc(F)cc1NCC(=O)N1CCCC(C(N)=O)C1 +O=C(c1scnc1C1CC1)N(CCc1cccc(F)c1)C1CC1 +N#CCCSc1nnc(N2CCOCC2)n1Cc1ccco1 +Cc1[nH]c2ccccc2c1C(=O)C(C)Sc1cc(C#N)ccn1 +Cc1ccc(N2CCCC(N(C)CC(O)CN3CCOCC3)C2)nn1 +CN(C)c1ncncc1N1CCC(C(=O)NCc2ccccc2)CC1 +CCOC(=O)c1cc(CCOc2ccccc2)n[nH]1 +O=C(NCCCN1CCOCC1)Nc1ccc2occc(=O)c2c1 +COc1cccc(C(=O)OCc2noc(-c3ccc(F)cc3)n2)c1F +CC(C)C(=O)c1ccc2oc(-c3cccnc3)nc2c1 +COCCN(CCC#N)Cc1c(F)cccc1F +CCCc1ccc(-c2nccn2CCN2CCCC2=O)o1 +Cc1ncsc1C(=O)N1CCN(Cc2noc(C3CC3)n2)CC1 +N#Cc1ccc(CC(=O)N2CCN(C(=O)c3cccc(O)c3)CC2)cc1 +Cn1nccc1C(=O)NC1CC(=O)N(Cc2ccc(F)cc2)C1 +Cc1cnn(CCC(=O)NC2CCCNC2=O)c1 +CCOC(=O)c1nc2sc(-c3cccc(C)c3)nn2c1CO +COC(=O)CCc1csc(Cc2ccccc2C)n1 +CCc1cccc(C)c1NC(=O)CSc1nnc(SC)s1 +CCOc1cc(C)ccc1NC(=O)c1csc(-c2ncccn2)n1 +CC(C)(C)c1cnc(CNC(=O)Cc2ccc(F)c(F)c2)o1 +COCC(=O)N1CCC2C1CCC(=O)N2c1cnn(C)c1 +CC1(NC(=O)Nc2cccc(C(=O)NC3CC3)c2)CCCC1 +CC(C1CC1)N(C)C(=O)C1CC(=O)N(c2cccc3ccccc23)C1 +CC(C)Oc1ccc(C(=O)NCCc2nnc3ccccn23)cc1 +Cn1nnc2c(=O)n(CC=Cc3ccccc3)cnc21 +CCOc1ccc2c(c1)CN(Cc1cnnn1C)CC2 +CCn1ncc(CN2CCN(C(=O)c3ccnn3C)CC2)c1C +O=C(NCc1ccccn1)NC(c1ccccc1)c1ccc(F)cc1 +O=C(Cc1cccc(O)c1)Nc1ccc(-c2nnc3n2CCCC3)cc1 +O=C1Nc2ccc(Br)cc2C1(O)Cc1ccncc1 +CC1Cc2ccccc2N1C(=O)CNS(=O)(=O)c1cn(C)cn1 +CCCn1ncc(N2CCC(C(=O)NCC3CCCO3)CC2)cc1=O +CCOC(=O)CCC(C)NC(=O)c1ccccc1Cl +Cc1nc(-c2ncccn2)sc1C(=O)OCc1cccc(F)c1 +CC(=O)c1cccc(OCCCC(=O)Nc2ccc(F)c(C#N)c2)c1 +Cc1cc(C)cc(-c2ccc(CN3CCn4c(n[nH]c4=O)C3)cc2)c1 +CC(C(N)=O)n1cc(CO)c2cc(Cl)ccc21 +O=C(NCc1ccccc1Cn1cncn1)NCC1CC=CCC1 +Cc1nc(NC(=O)OC(C)(C)C)ccc1Br +CC1CN(C(=O)c2ccc(N3CCOC3=O)cc2)CCO1 +Cc1cc(CN2CCN(C(=O)Nc3ccccc3N(C)C)CC2)on1 +CNC(=O)CN1C(=O)C(C)(C)C(=O)c2ccc(N)cc21 +CC(C)NS(=O)(=O)c1ccc(NCc2ccc(F)cc2)cc1 +Cc1ccc(CSc2nnc(CO)n2C2CC2)cc1 +O=C(CNC(=O)c1ccc(F)c(F)c1)Nc1ccccc1F +COc1ccc(OC)c(C2NC(=O)c3[nH]nc(-c4cccs4)c32)c1 +CCOc1ccc(OC)cc1NCc1nnc(C(C)(C)C)o1 +COc1cccc(C(=O)N2CCCC2c2ccncc2)c1OC +CC(C)COc1ccccc1-c1cc(C(C)(C)O)c(=O)[nH]n1 +COc1ccccc1NC(=O)CNc1cc(NC(C)=O)ccc1C +Cc1cc(CC(=O)N2CCCC(C)(c3ccccc3)C2)on1 +Cc1cccc(OC2CCN(C(=O)Cc3ccc(CO)cc3)CC2)c1 +COc1ccc(OC)c(CN2CCN(c3ncccn3)CC2)c1 +N#Cc1ccsc1NC(=O)CSc1ccc2ccccc2n1 +C=CCOC1CC2(CCN(C(=O)c3ccnnc3)CC2)C1 +COCCN(CCC#N)C(=O)c1cnc(N)c(Cl)c1 +CC(Sc1nnc(-c2cccnc2)n1Cc1ccco1)C(N)=O +Cc1cccc(C(=O)N(Cc2cccnc2)c2ccc(F)cc2)n1 +Cn1c(=O)ccn(CC(=O)N2CCCC2C2CCCC2)c1=O +Cc1ccc(N2CCC(NC(=O)NCCC(C)C)C2=O)cc1C +CC(=O)c1ccc(F)c(NC(=O)c2ccccc2)c1 +COc1ccc(NC(=O)COc2ncnc3ccccc23)cc1 +Cc1cc(NS(=O)(=O)c2ccc(Br)cc2F)nn1C +O=C(NCCCC(=O)N(C1CC1)C1CCc2ccccc21)C1CC1 +c1ccc(CN2CCOC3(COCCN(c4nccs4)C3)C2)nc1 +Cc1cc(C)cc(OCn2ccc(C(=O)N3CC(C)OC(C)C3)n2)c1 +O=C(NCc1ccccc1N1CCCCC1)c1ccoc1 +CSc1cccc(NC(=O)Cn2ccc3sccc3c2=O)c1 +O=S(=O)(NC1CC1)c1cccc(Br)c1 +CC(C)n1nccc1C(=O)Nc1ccc(O)c(Cl)c1 +Cc1ccccc1CNC(=O)c1cc(N2CCCC2=O)ccc1Cl +COc1ccccc1NC(=O)c1cnc2ccc(C)cn12 +Nc1ncn(CC(=O)NCCc2ccc(Cl)cc2Cl)n1 +COC(=O)CCNC(=O)c1ccc(Br)cc1Cl +Cc1ccc(CC(=O)NCCOc2ccccc2)cc1 +CC1Cc2ccccc2N1C(=O)NCCNC(=O)c1ccccc1 +COc1ccc2[nH]cc(CC(=O)NC(C)c3nnc4ccccn34)c2c1 +Cc1cc(C)c(OC(=O)Cc2csc(C)n2)c(C)c1 +CCOc1ccccc1C(=O)NCC(=O)Nc1ccc(C(C)=O)cc1 +CN(C)c1ccc(C(=O)NCCNc2ncccc2C#N)cc1F +COc1cc(C#N)ccc1OCC(=O)N=c1[nH]nc2ccccn12 +CN(C(=O)c1ccno1)c1nnc(-c2cnccn2)s1 +Cc1ccc(S(=O)(=O)C2(C(=O)NCCc3ccccc3)CC2)cc1 +O=C(CN1CCN(Cc2cccs2)CC1)NC1CCCC1 +O=C(CNC(=O)c1cccs1)OCc1ccccc1 +CC1CN(S(=O)(=O)N2CCCCCC2)CC1(O)C1CCC1 +CC(C)CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C#N +CCCNc1ncnc(NCc2ccccc2Cl)c1N +Cc1ccncc1NC(=O)NCc1cc(C(C)C)no1 +CC(C)C(=O)Nc1cccc(NC(=O)c2ccccc2F)c1 +CCOc1ccc(-n2nc(CO)c(=O)cc2C)cc1 +Cc1ccc(C(C)NC(=O)c2cc3ccccc3[nH]2)o1 +CC(C)CCC(C)(O)CNC(=O)c1c[nH]c2cccc(F)c12 +Cn1c(C(=O)Nc2ccccc2)nnc1-c1ccc(O)cc1 +CNC(=O)CSc1nnc(-c2ccncc2)n1-c1ccccc1C +Cc1cccc(OC2CCN(C(=O)CC(C)N3CCOCC3)CC2)c1 +Cc1noc(C2CCCN2S(=O)(=O)c2c(C)noc2C)n1 +CCOC(=O)CCn1nc(C(C)(C)C)c2c1CCCC2=O +O=C(OCCCn1nc2ccccn2c1=O)c1ccccn1 +Cc1ccccc1-n1cc(C(=O)N(C)CCOCC2CC2)cn1 +CCc1ccc(S(=O)(=O)N(C)Cc2cccc(C#N)c2)s1 +Cc1ccncc1NC(=O)NC(C)CC(O)c1ccccc1 +CC(C(=O)NC1CCSc2ccc(Cl)cc21)n1cccn1 +CN(C)c1nc(N)nc(COc2ccc(C(F)(F)F)cc2)n1 +CCC1COCCN1Cc1ccc(OC)c(COC)c1 +Cc1cc(OCc2nc(CC(=O)NC3CCCC3)no2)ccc1Cl +CC(=O)c1csc(-c2csc(CCN3CCOC3=O)n2)c1 +CC(C)Cc1nc(-c2nc3c([nH]2)CC(C)(C)CNC3=O)no1 +NS(=O)(=O)c1cccc(S(=O)(=O)NCc2cn[nH]c2)c1 +Cc1cc(CNc2nnc(C(C)C)s2)ccc1-n1cncn1 +O=C(Nc1ccsc1)c1csnc1C(F)F +CN(CCc1ccccc1)C(=O)Nc1cccnc1 +COc1ccc(CC(C)CNC(=O)c2csc(NC(C)=O)n2)cc1 +COCCCNc1nc(C)nc2scc(-c3ccccc3)c12 +O=C(NCCNC(=O)C1CC1)Nc1ccc(Br)cc1 +COc1ccc(Nc2nc(N)c(C(=O)C(C)C)s2)cc1OC +Cc1nc2c(c(S(=O)(=O)N3CCOCC3)nn2C)c(C)c1Cl +COC(=O)C1=C(C)Nc2ncnn2C1c1ccc(Cl)c(Cl)c1 +CC(C)CNC(=O)C(NC(=O)c1cnc2cccnn2c1=O)C(C)C +COCCCn1c(C2CC2)nc2ccc(Cl)cc21 +CC(=O)Nc1ccc(F)c(NC(=O)CC(C)(C)C)c1 +CC(=O)Nc1ccc(C(=O)Nc2ccc(C)cc2)s1 +COc1ccccc1CN(C)C(=O)c1ccc(S(C)(=O)=O)cc1 +O=C(NCC1CN2CCCCC2CO1)Nc1cccc(F)c1 +CCNC(=O)N1CCC(Nc2cc(C3CC3)ncn2)CC1 +O=C(COc1ccc2ccc(=O)oc2c1)NCCc1ccccc1 +O=C(NCCCCOc1ccc(F)cc1)c1n[nH]c(=O)[nH]1 +Cc1ccc(NC(=O)N(C)Cc2ccncc2)cc1 +Cc1ccc(CNC(=O)c2sc(-n3cccc3)nc2C)cc1 +CN(C)S(=O)(=O)c1cccc(C(=O)NCCc2ccco2)c1 +Cc1nc2ccc(NC(=O)COc3ccccc3C#N)cc2s1 +COc1cccc(NC(=O)c2c(-n3cnnn3)sc(C)c2C)c1 +Cc1cc(NC(=O)C2(c3ccc(F)cc3F)CCOCC2)ccn1 +CCn1cc(C(=O)NCc2ccccn2)c(=O)c2cc(OC)ccc21 +CCS(=O)(=O)NCC12COCC1CN(Cc1nc(C)cs1)C2 +CN(Cc1cc(Cl)cn1C)C(=O)Nc1cccc2[nH]ccc12 +COc1ccc(C(NC(=O)Cc2ccc[nH]2)C(C)C)cc1 +Cn1cc(CCC(=O)N2CCCCC2)c2ccccc21 +O=C(CN1CCc2ccccc21)NCCCc1nnc2n1CCCC2 +Cc1ccc(CN(C(=O)c2ccccc2F)c2ccccn2)o1 +Cc1onc(-c2ccccc2)c1-c1nnc(CN2CCOCC2C)o1 +CCc1ccc(CN2CCN(c3ncc(Cl)cn3)CC2)nc1 +Cc1cc(C)cc(C(=O)N(C)Cc2ccc(O)cc2)c1 +N#CCc1ccc(NC(=O)Cn2cnc3sccc3c2=O)cc1 +COc1cccc(CC(=O)Nc2ccc(OC)cc2N)c1 +NC(=O)Cc1ccccc1NC(=O)NC1(c2ccc(F)cc2)CCC1 +CCCNC(=O)CN1CCNc2cc(F)ccc21 +CC(C)c1ccccc1NC(=O)CCn1cnc2sccc2c1=O +Cc1cc2nc(NCc3ccc(NC(N)=O)cc3)c3ccccc3n2n1 +CC(Sc1nnc(-c2ccc(Cl)cc2)o1)C(=O)N(C)C +COCCNC(=O)Nc1ccc(OCC(C)C)c(Cl)c1 +CC1CN(C)CCN1C(=O)c1nc(N2CCOCC2)ncc1Cl +O=C1Nc2cc(F)ccc2C1Nc1ccccc1Br +O=S(=O)(Nc1cn[nH]c1)c1cccc(-c2nnco2)c1 +CCc1ccc(CCC(=O)N(Cc2cccnc2)C2CC2)cc1 +COc1ccc(Br)cc1S(=O)(=O)Nc1ccccc1 +CCOCC(=O)N1CCC2(CC1)Nc1ccccc1NC2=O +Cc1nc2c(s1)CCCC2NC1=NC=NC2=NC=NC21 +CCc1ccc2c(c1)C(O)(CC(=O)c1ccc(F)cc1)C(=O)N2 +COc1ccc(N)c(C(=O)NCc2ccccn2)c1 +CC(=O)c1csc(NC(=O)COc2cc(Cl)ccc2Cl)n1 +COCCOC1CC2CN(C(=O)Cc3cccc(F)c3)CCN2C1 +CCN(CC)C(=O)Cc1csc(NC(=O)NC2CCCC2)n1 +CCN(CC)S(=O)(=O)c1ccc2c(c1)C(C)(C)CC(=O)N2 +CCc1nc2cc(NC(=O)c3cc(-c4ccccn4)n[nH]3)ccc2n1C +Cn1c(N2CCN(C(=O)c3ccccc3)CC2)cc(=O)n(C)c1=O +CS(=O)(=O)N1CCCCC1C(=O)NCCc1ccccn1 +COc1cc(CNCC(O)c2ccccc2Cl)cc(OC)c1 +CCOc1cccc(CS(=O)(=O)c2ccccc2C)n1 +Nc1cc(C(=O)CCC(=O)NC2CC2)ccc1Cl +CCN(C(=O)c1cc(C)n(-c2ccccc2)n1)C(C)C(C)C +Cc1cc(C)c2c(N3CCOC4(CCCC4)C3)ncnc2n1 +CC(C(=O)NCc1cccnc1)N(c1ccccc1)S(C)(=O)=O +Cc1cccc(C)c1CNc1c(C)cccc1C(N)=O +CC(C)Cc1noc(CN(C)Cc2ccnc3ccccc23)n1 +CCN(CC)C(=O)CNc1cc(Br)ccc1C +COc1cccc(CNC(=O)c2c[nH]nc2-c2ccc(F)cc2)c1 +Cc1ccc(C(=O)Nc2ccccc2NC(=O)CC2C=CCC2)c(C)n1 +CC(C)NC(=O)CCNC(=O)NC1c2ccccc2CC1O +FC(F)(F)c1ccc(N2CCCCC2)c(-n2cnnc2)c1 +NC(=O)CN(c1ccc(Cl)cc1)S(=O)(=O)c1ccccc1 +O=C(C1CC1c1cccnc1)N1CCCC(c2ccn[nH]2)C1 +NC(=O)C1CCC(CNC(=O)CCCc2cc(F)ccc2F)CC1 +CC(CNC(=O)C1(C#N)CCCC1)CN(C)C(=O)OC(C)(C)C +Cc1cc(-c2nn(CC(=O)Nc3ccnn3C)cc2C)c(C)s1 +CCCNC(=O)CCC(=O)NC1(C)Cc2ccccc2C1 +Cc1nn(C(C)C)c(C)c1NCc1ccccc1F +Cc1ccc(C(=O)NCCCc2cn[nH]c2C)cc1C +CCN(Cc1cccs1)C(=O)c1ccc(NC)nc1 +CN(C)S(=O)(=O)c1cccc(CNc2ccccc2C(N)=O)c1 +CCc1nnc2n1CCN(C(=O)CCn1c(=O)oc3ccccc31)C2 +CN(Cc1cnc(N2CCOCC2)nc1)Cc1cccn1C +O=C(CSc1ccncc1)N1CCN(C(=O)c2ccco2)CC1 +CCc1cc(=O)oc2cc(OCCn3cccn3)ccc12 +CCc1nn(C(C)c2ccccc2)c2c1C(CC#N)CCC2 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(Cl)ccn1 +Cc1nc(CN2CC3CN(C(=O)C4(C#N)CC4)CC3C2=O)cs1 +Cc1cc(CC(=O)N2CCCC(C(=O)N3CCC(C)CC3)C2)no1 +O=c1[nH]ncc(-c2ccc(Cl)cc2Cl)c1CO +COc1coc(C(=O)Nc2ccc3c(c2)nc(C(C)C)n3C)cc1=O +O=c1oc(-c2ccc(F)cc2)nn1CC(O)c1ccccc1F +COc1ccccc1NC(=O)CN1CCN(c2ccccc2)C1=O +CNc1nc(C)c(C(=O)OCc2ccccc2)s1 +Cc1ncc(CC(=O)N2CCC(C(=O)N3CCCCC3)CC2)c(=O)[nH]1 +O=C(Cn1cc(CO)nn1)NCc1ccc(Cl)cc1 +CCOC(=O)c1c(-c2ccc(F)cc2)cn2c1SCC2=O +CCN(CC)C(=O)c1ccc(S(=O)(=O)C(C)C)cc1 +CCCOc1ccc(C(=O)NC(C)C2CCCO2)cc1 +CCCCn1nnc(NC(=O)c2ccc(C)c(C)c2)n1 +Cc1ncoc1C(=O)N1CCCC(CCc2cccc(F)c2)C1 +Cc1cc(C)c(CN2CCOC(c3cnn(C)c3)C2)cc1C +O=C(Cn1cnnn1)NCC12CC3CC(CC(C3)C1)C2 +c1ccn2cc(CSc3nnc(N4CCCC4)s3)nc2c1 +CC(=O)NCCNC(=O)N1CCC(CCC(C)C)CC1 +O=C(c1c[nH]c(=O)[nH]c1=O)N1CCN(Cc2ccc(Cl)cc2)CC1 +CC(=O)c1ccc(N2CCC(C(=O)NCC3CC3)CC2)cc1 +O=C(Nc1cccnc1)NC1CC(=O)N(c2ccc(F)cc2)C1 +CCC(C)NC(=O)Nc1cn(C)c(=O)c2ccccc12 +CCc1onc(C)c1NC(=O)NC1CCCC2OCCC12 +CCN(C)C(=O)C(C)NC1=NS(=O)(=O)c2ccccc21 +CC(C)Cc1noc(CCNS(=O)(=O)c2ccccc2)n1 +Cc1cc(C)n(CC(=O)NCc2cccc(O)c2)n1 +CC(Cn1cncn1)NS(=O)(=O)Cc1ccccc1Cl +CCOc1ccc(C(=O)NCc2nnc3ccccn23)cc1OC +CC(=O)N1CCN(Cc2nc3cc(Cl)ccc3n2C)CC1 +Cc1cccc(OCC(=O)Nc2ccc3nc(C)oc3c2)c1 +CCc1nc2cc3c(cc2n1CC(C)C#N)OCCO3 +Oc1ccc(CNc2ccc(C(F)(F)F)nc2)cc1 +CN1CC(C(=O)N(C)Cc2cc(Br)ccc2F)CC1=O +CCOC(=O)c1cncc(NCCNC(C)=O)c1 +CCCCN(C)C(=O)c1coc(COc2cccc(F)c2F)n1 +CC(NC(=O)CCc1ccccc1)c1ccc(O)cc1 +CC(C)COCCCC(=O)Nc1ccc(F)cc1N +CCOc1cccc(C(C)NC(=O)NCC(=O)NC)c1 +COCCN(Cc1cccc(Cl)c1F)C(C)C(N)=O +O=C(NCC(c1ccccc1)N1CCOCC1)c1cc(C2CC2)on1 +Cc1ccc(C)c(OCC(=O)NCc2ccncc2)c1 +Cc1ccc(-c2nnc3n2NC2CCCC2S3)cc1 +CC1CC(C)CN(S(=O)(=O)c2ccccc2S(C)(=O)=O)C1 +COc1ccc(N2CCC(C(=O)Nc3ccccc3)CC2)nn1 +CCC(C)NC(=O)C(C)S(=O)(=O)c1ccc(O)cc1 +CC(C)n1nccc1NC(=O)NCc1cccnc1OC1CCCC1 +NC(=O)CCCNC(=O)Nc1ccccc1Cl +CC(=O)NC1CN(c2nc(C)cc(C)c2C#N)CC1c1ccc(C)o1 +CCN(CC(=O)NC)C(=O)Cc1cccc(O)c1 +Cc1nc(N2CCCC(C)C2)nc2c1C(=O)CC(c1ccco1)C2 +Cc1cc(C(=O)NC(C)CO)c(C)cc1Br +COC(=O)Cn1ncc2c3sc(C)cc3n(C)c2c1=O +CC1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1cccc(CC#N)c1 +CC(C)(C#N)c1ccc(NC(=O)CCNC(=O)C2CCCC2)cc1 +Cc1csc(NC(=O)CCC(=O)Nc2nccs2)n1 +CCOc1ccc(C(=O)N2CCCCC2CC)cc1OC +Cc1ccc2c(c1)-c1c(cnn1CC(=O)N1CCCC1)CO2 +CCOC(=O)c1ccn(-c2ccc(NC(=O)Cc3ccc[nH]3)cc2)n1 +Cn1c(CNC(=O)c2ccc(F)c(F)c2F)nnc1C1CCC1 +O=C(Nc1nc2ccc(F)cn2n1)c1ccc(F)nc1 +NC(=O)c1cc(C2CCCN(Cc3nnc(C4CCC4)o3)C2)n[nH]1 +Cc1nc(-c2cccc(NC(=O)COC(=O)c3ccoc3)c2)cs1 +Cc1ccc(NCC(=O)NCC2COc3ccccc3O2)cc1C +CCCCC(=O)Nc1cccc(NC(=O)NCC)c1 +CC(NC(=O)c1ccc[nH]c1=O)c1cccc(Cl)c1 +CC(=O)N(C)c1ccc(NC(=O)c2ccccc2Br)cc1 +CC(=O)Nc1cc(C(=O)Nc2ccc3ccccc3c2)ccc1F +COc1ccc(C(=O)NC(C)(C)C)cc1Br +COCC(=O)N1CCN(C(=O)c2ccc(C)s2)CC1 +Cc1cc(OCC(=O)N(c2ccccc2)C(C)C)nnc1C +CC(Sc1nnc2n1CCCCC2)C(=O)c1ccc(F)cc1F +CCS(=O)(=O)N1CCN(c2nc(-c3ccsc3)cs2)CC1 +O=C(CSc1ccccc1)NCCCn1nc2ccccn2c1=O +CCOc1ccc(CCCNS(C)(=O)=O)cc1 +CC(C(=O)Nc1ccc(C(N)=O)cc1)N1CCCc2ccccc21 +Cc1nc(N(C)C)nc2c1COCC21CCN(Cc2cccnc2)C1 +Nc1cnc(N2CCCCC2CCO)c(Br)c1 +CCOc1ccc(C(=O)Nc2cccc(C#N)c2)nn1 +CCCCCCC(=O)Nc1ccccc1C(=O)N(C)C +COc1ccc(NC(=O)c2cc(OC)c(OC)c(OC)c2)c(OC)c1 +Nc1ccc2c(c1)ncn2Cc1ccccc1Cl +O=C(NCc1ccn(-c2ccccc2F)n1)c1cc(C2CC2)[nH]n1 +O=C(NC1CCCNC1=O)c1ccc2c(c1)OCO2 +O=C1CC(C(=O)N2CCCC(c3ccn[nH]3)C2)CN1CC1CC1 +COC(C)c1nc(Cc2nc3scc(C)c3c(=O)[nH]2)cs1 +NC(=O)Nc1ccc(C(=O)OCC(=O)c2ccc[nH]2)cc1 +COc1cccc(-n2nnc(CO)c2-c2cccc(F)c2)c1 +CC(=O)c1cccc(OCC(=O)NC2CCCc3ccccc32)c1 +CN(CC(=O)N1CCOCC1)C(=O)CSc1ccc2c(c1)CCC2 +CC1CCC(C(N)=O)CN1C(=O)c1ccc(=O)n(-c2ccccc2)n1 +C#Cc1cccc(NC(=O)c2scnc2C2CC2)c1 +CN(Cc1nccn1C(F)F)S(=O)(=O)c1c(F)cccc1F +O=C(CN1CCCC1=O)NC(Cc1cccs1)c1nccs1 +Cc1cc(C)n(-c2cccc(C3CC(=O)Nc4n[nH]cc43)c2)n1 +CC1CN(C(=O)c2ccc3c(c2)OCCO3)CC(C)O1 +O=C(Nc1ccc(NC2CCOCC2)cc1)c1scnc1C1CC1 +CCOCCCNc1ncnc2c1[nH]c1ccc(F)cc12 +CCOc1ccccc1NC(=O)c1cnn(-c2ccc(F)cc2)c1 +COCCN1CCC2(CN(C(=O)c3cnccn3)CC2C)C1=O +CCCCc1ccc(-n2nnnc2SCC(=O)NC)cc1 +O=C(Nc1nc[nH]n1)c1ccn(-c2ccccc2Cl)n1 +OCCNc1ncnc2ccc(-n3ncc4cccnc43)cc12 +COc1cc(Cl)ccc1C(=O)Nc1ncnn1C +CCN(CC)S(=O)(=O)CC(=O)NC(C)c1ccc(C)cc1 +CCCS(=O)(=O)N1C(C(N)=O)CC2CCCCC21 +O=C(Nc1ccc(OC(=O)C2CC=CCC2)cc1)c1ccco1 +NC(=O)C1CCN(C(=O)c2ccc(-c3cscn3)cc2)CC1 +Cc1csc(CNC(=O)C2CCC(NC(=O)C3CCCC3)CC2)n1 +COCC(C)N1CCN(C(=O)CNC(=O)C2CCCC2)CC1 +Cc1nccc(CNC(=O)NCc2cnn(C)c2)n1 +O=C(CN1C(=O)CNc2cc(F)c(F)cc21)Nc1ccccn1 +NC(=O)C(NCC(F)(F)F)c1cccc2ccccc12 +CCCCn1nc(C(=O)NC(C)c2cc(C)sc2C)ccc1=O +CN(Cc1cccc(Cl)c1)S(=O)(=O)c1ccc(C(N)=O)cc1 +COc1ccc(F)c(NC(=O)C(NC(=O)c2ccccc2)C(C)C)c1 +O=C(CSc1nnnn1C1CC1)Nc1ccc2c(c1)CCC2 +Cc1cc2oc(C(=O)NC3CCCOC3)cc(=O)c2cc1C +O=C(Cc1ccc(Br)cc1)c1c(O)cc(O)cc1O +CC(c1ccccc1)S(=O)(=O)c1cccs1 +CC1(C2CCN(C(=O)c3ncoc3-c3cccs3)CC2)OCCO1 +COC(=O)CCCC(O)c1ccc2c(c1)CC(=O)N2C +CCCOC1CCCN(C(=O)Nc2ccc(F)cc2)C1 +COC(=O)C1=C(C)C(C(=O)N(C)Cc2ccccc2C)=NC1C +Nn1c(SCC(=O)N2CCCC2)nnc1SCc1ccccc1 +O=C(CCc1cncc(F)c1)Nc1cccc(Cl)c1O +COc1cc2c(c(OC)c1)C(c1ccoc1)NCC2 +CN1CCN(C(=O)COc2cc(=O)n(C)c3ccccc23)CC1 +Cc1c(C(=O)Nc2cccc(F)c2)sc2nc[nH]c(=O)c12 +COc1cccc(-c2nnc(NC(=O)C(C)C)s2)c1 +CSc1ccccc1NC(=O)CSc1nc(=O)[nH]c(C)c1C#N +CCCCC(=O)Nc1sc2c(c1C(N)=O)CCN(C(C)=O)C2 +COc1cc(NC(=O)CSc2nn3cnnc3o2)cc(OC)c1 +Cc1ncc(Br)c(-c2ccc(F)cc2F)n1 +CCc1ccccc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +Cc1cc(C)n(Cc2ccc(C(=O)NCCCn3ccnc3)o2)n1 +COC(=O)Nc1cccc(NC(=O)NCCCc2c(C)noc2C)c1 +Cn1cc(CNC(=O)C2CCCCN2S(C)(=O)=O)cn1 +COCCOCC1NCCc2cc(C)c(O)cc21 +CCCn1ncc(-c2ccc(F)cc2F)c(N)c1=O +N#CCCCOc1cccc(NCc2cc3ccccc3[nH]c2=O)c1 +COC(=O)NC(C(=O)NCc1cn(-c2ccccc2)nn1)C(C)C +CC(C)Oc1cccc(-c2cc(N3CCOCC3)nc(N)n2)c1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2cccc(C(C)=O)c2)cc1 +O=C(c1ccc(-c2ccn[nH]2)cc1)N1CCC(Oc2cccnc2)CC1 +Cc1ccc(N)cc1S(=O)(=O)NCC1COCCO1 +C=C(C)CN(CC)C(=O)Cn1cc(C(=O)OC)cc(C#N)c1=O +CCNc1ncc(C(=O)NC(CC)CC)cc1Cl +C=CCNC(=O)NC(CC)c1ccccc1OC(F)F +CCn1c(=O)cc(SCC(=O)NC2CCCC2)c2ccccc21 +CC(C)Cn1ncc(C(=O)NC2CCCCC2C)c1C1CC1 +COC(=O)CC(C)Nc1cc(OC)ccc1OC +COc1ncnc(N(C)C)c1NC(=O)C1CCC(F)(F)CC1 +Cn1c(C2CC(=O)N(c3ccc4c(c3)OCCO4)C2)nc2ccccc21 +CCOc1ccccc1C(=O)NCC1CCN(C(=O)OC)CC1 +CCC(CCNC(=O)c1ccc(F)c(C)c1)N1CCCC1=O +COc1ccc(-n2cc(CNc3cn[nH]c(=O)c3Cl)nn2)cc1 +CCCC(=O)N1CCN(S(=O)(=O)c2cccs2)CC1 +Nc1ccc2c(c1)nc(CC(F)(F)F)n2-c1ccncc1 +O=S(=O)(c1ccc2c(c1)OCCO2)N1CCC(CO)CC1 +Cc1c(NC2C=CC(CO)C2)nn2c(C(F)(F)F)nnc2c1C +O=C(Cc1nnc(-c2ccsc2)o1)Nc1ccc(Cl)cc1 +CCc1noc(CC)c1CC(=O)N1CCOCC1 +CC(C)CCCC(C)NC(=O)Cn1c(=O)c(=O)[nH]c2ccccc21 +COc1cc(NC(=O)c2n[nH]c3ccc(C)cc23)ccc1NC(C)=O +CN(Cc1cnccn1)C(=O)Nc1ccc(F)c(Br)c1 +Cc1cc(C(=O)N2CCN(C(C)c3nnc(C)o3)CC2)on1 +CNc1nnc(-c2c(COC)oc(C)c2C)s1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(OC)c(OC)c1 +COC1CCCC(OC(=O)c2cccnc2OCC(F)F)C1 +CC(C)n1nnc(CC(=O)NCCOc2ccc(F)cc2)n1 +COc1cccc(CNc2nnnn2C)c1OCC(N)=O +COc1cc(Cl)ccc1C(=O)NC1CCCCNC1=O +O=C(NCC1CN2CCCCC2CO1)NCC1(c2ccccc2)CC1 +Cn1cnnc1CNc1ncc(Br)cc1N +C=CCOC(=O)c1nnc2c(-c3ccccc3OC)cnn2c1C +Cc1nc(NCc2ccc(Cl)cc2)cc(-c2cccnc2)n1 +COCCNC(=O)COc1c(Cl)cc(N)cc1Cl +O=C(Nc1ccc(OC(F)F)c(F)c1)c1ccco1 +CCc1nc(CN2CCN(C(=O)CO)CC2)no1 +Cc1cc(NC(=O)COC(=O)c2cc(Br)c[nH]2)n(C)n1 +CNC(=O)C1(NS(=O)(=O)c2cccnc2)CCCCC1 +CC1CC1CNC(=O)c1ccc(CCNS(C)(=O)=O)s1 +Cc1cc(F)ccc1NC(=O)CCn1cnc2c(cnn2C)c1=O +COc1ccc(S(=O)(=O)NCc2ccsc2)cc1C +CC(=O)Oc1ccc(NS(=O)(=O)c2ccccc2)cc1 +CC1CC(C)CN(C(=O)CCc2ccsc2)C1 +Nc1cc(C(=O)NCc2ccccc2Cl)ccc1Cl +COCCN1CC(C(=O)NCC2CCN(c3ccccc3)C2)CC1=O +COC(=O)c1ccc(-n2nnnc2SCC(=O)NC(C)(C)C)cc1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCc2cnn(C)c2C)n1 +N#Cc1ccccc1NCc1cc(F)c(F)c(F)c1 +O=C(NCc1cnn2cccnc12)c1ccc(C2CCCO2)s1 +Cn1nnc2c(NCc3ccccc3Cl)ncnc21 +Cc1nc(-c2cccs2)ccc1C(=O)Nc1nccs1 +Cc1occc1C(=O)Oc1cccc(NC(=O)CN2CCCC2=O)c1 +Cc1csc(=O)n1CCC(=O)NC1CCN(c2ncccn2)CC1 +O=C(CC1CCCO1)NC1CCc2c(Cl)cccc21 +COc1ccccc1C(=O)CCCC(=O)NC1CCCC1 +O=C(Nc1cccnc1)C1CCN(C(=O)c2ccc(F)cc2F)CC1 +C=C(C)COc1cccc(C(=O)Nc2ccc(NC(C)=O)cc2)c1 +CN(C)C(=O)c1cccc(NC(=O)c2ccc3c4c(cccc24)CC3)c1 +Cc1cc(NC(=O)c2ccco2)n(-c2ccc(F)cc2)n1 +O=C(NCc1ccc2c(c1)OCO2)c1cc2ccccc2o1 +Cc1nn(C)c2ncc(NC(=O)c3ccc(F)cc3Cl)cc12 +CC(=O)N(CCc1ccccc1)CC(=O)NCC1(C)CCCC1 +CCC(C(=O)NCc1ccc2c(c1)CC(C)(C)O2)n1cccn1 +O=C(Nc1ccn(Cc2ccccn2)n1)c1cc(Cl)ccc1F +COc1ccc(CCC(C)NC(=O)NC(C)c2ccncc2)cc1 +COc1ccc(C(CNCc2ccc(F)cc2F)N(C)C)cc1 +O=C1CC(c2ccncc2)C2(CCN(S(=O)(=O)C3CC3)CC2)N1 +COCCCNS(=O)(=O)c1cc(C(C)=O)ccc1C +NC(=O)c1ccc(NC(=O)NCc2ccnc(OC3CCC3)c2)cc1 +CCN(CC)S(=O)(=O)c1ccc2[nH]c(-c3ccc(O)cc3)nc2c1 +Cc1cc(C)c2c(c1)NC(NC(C)(C)CO)=NS2(=O)=O +CCc1cn[nH]c1C1CCCN(Cc2cc(C(C)=O)cn2C)C1 +CCCn1nc(-n2cnnc2)c(NC(=O)c2cccc(C)c2)c1C +C=CCN1CCN(C(=O)C(C)Oc2ccc(F)cc2)CC1 +COCCn1cc(NC(=O)Nc2cccc(OC)c2)c2ccccc21 +O=C(CSc1nccn1Cc1ccccc1)c1ccc[nH]1 +COc1ccccc1C(O)CNC(=O)Cc1ccc(F)cc1 +CC1CCc2c(C(=O)N3CC(C(N)=O)CCC3C)csc2C1 +Cc1ncnc(-c2ccc(Br)cc2)c1C +COc1cc(N)c2ccnc(C(=O)Nc3ccncc3)c2c1OC +O=S(=O)(c1cccnc1)N1CCN(c2ccccn2)CC1 +COCC(NC(=O)CCc1ccc(Br)c(C)c1)C(N)=O +CC1=CC(C)=NC(=O)C1CNC(=O)Cn1ccc(C(F)(F)F)n1 +O=C(NCc1cccnc1)c1cc(Br)ccc1Cl +CCOCCNC(=O)C1CC1c1ccc(Br)cc1 +CCn1cnnc1C1CCN(C(=O)c2cnc(C)s2)CC1 +Cn1c2ccccc2n2c(SCC(=O)Nc3ccccc3)nnc12 +CCn1c(CN2CCOCC2)nc2cc(NC(=O)CC(C)C)ccc21 +CC1(C(=O)N2CCCCC2CN2CCOCC2)CC1(Cl)Cl +Cc1ccc(C(=O)N2CCC3C2CC(=O)N3c2cccnc2)cn1 +CC(C)NC(=O)CCNC(=O)Nc1ccc(F)cc1C#N +CNC(=O)CN(C)C(=O)c1ccc(N2CCOCC2)cc1 +COc1ccc2c(c1)CCc1cc(C(=O)N3CCC3)sc1-2 +COCCCn1ccc(NC(=O)N(C)Cc2cccc(Cl)c2)n1 +O=C1CCC2(CC1)Cc1ccc(Br)cc1C2=O +COCc1ccc(C(=O)Nc2cc(C)nn2-c2ccc(C)cc2)o1 +CN(C)S(=O)(=O)c1ccccc1CNC(=O)Cn1ccccc1=O +Cc1cccc(C)c1-n1nnnc1SCCCc1cnn(C)c1 +COc1ccc(C(O)CNc2ccccc2C)cc1 +CCOC(=O)N1CCN(C(=O)C2CC=CC2)CC1 +CCCC(C)NC(=O)COc1cc(F)ccc1N +COc1ccc(C(=O)N2CCc3c(N)cccc3C2)cc1OC +Cc1cc(C)nc(NC(=O)c2c(F)cccc2F)n1 +O=C(NCC(=O)N1CCOC2CCCCC21)NC1CCCCC1 +COC(=O)C1CC(O)CN1Cc1cc(C#N)n(C)c1C +CCCN(CCO)C(=O)Nc1ccc(CC#N)cc1 +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)N(c1ccccc1)C(C)C +CCc1cccc(OCC(=O)NCC2CCCO2)c1 +CC(C)(C)Oc1ccccc1NC(=O)Cc1ccc[nH]1 +CC(C)(C)c1ccc2oc(=O)cc(CNC(=O)C3CCCO3)c2c1 +O=C(Cc1c[nH]c2ccccc12)Nc1cccc2ncccc12 +Cc1n[nH]c(C)c1NC(=O)c1ccccc1Br +Cc1ccc(S(=O)(=O)NC2CCN(c3ccccc3)C2=O)c(F)c1 +CCCC(=O)Nc1sc2c(c1C(N)=O)CCC(C)C2 +Cc1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)c(C)c1 +O=c1cc(CN2CCOCC2)[nH]c2c(F)cccc12 +COc1cccc(C(=O)NCCNC(=O)c2ccc(C)c(F)c2)c1 +COc1cc(NC(=O)c2cncc(Br)c2)cc(OC)c1 +CC(CC1CCCC1)C(=O)NC1CCN(CC(F)(F)F)C1 +CCn1c(C2CC(=O)N(Cc3ccccc3)C2)n[nH]c1=O +CC(C)n1ncc2cc(C(=O)NC3CCCC3)c(N)nc21 +CC(C(=O)Nc1ccn(-c2ncccc2Cl)n1)C1CCOCC1 +O=c1c2cnc3nc(-c4ccncc4)nn3c2ccn1CC1CCCO1 +CC(C)C(=O)NCc1cccc(Oc2ccccn2)c1 +CS(=O)(=O)N1CCCC1c1cccc(Cc2ccc(F)cc2)n1 +O=C(Nc1nn2cc(-c3ccccc3)nc2s1)c1ccccc1F +O=C(Cc1ccccc1Cl)NC1CCCCC1O +Cc1nn(C)c(C)c1C(=O)NCCCn1cnc2ccccc21 +CC1COCCN1C(=O)c1ccc(-c2ccccc2)[nH]c1=O +c1ccc2c(c1)OCC(CNc1ncnc3[nH]cnc13)O2 +CC(C)c1nnc(NC(=O)C2(C)Cc3ccccc3C(=O)O2)s1 +CCCCn1c(=O)c2c(nc3n(CC)c(C)cn23)n(C)c1=O +Cn1ncc(N2CCN(C(=O)CN3CCCCCC3=O)CC2)cc1=O +CCOCCNC(=O)C1(c2ccc(F)cc2F)CCOCC1 +Cc1ccc(NC(=O)c2cc3c(cc2O)OCO3)nc1 +O=C1CN(c2ccccc2NS(=O)(=O)C2CCCCC2)CCN1 +Cc1cccc(C)c1NC(=O)C(O)c1ccc2c(c1)OCCO2 +COCC(=O)N1CCC(c2[nH]ncc2Cc2ccccc2)CC1 +COc1ccccc1C(NC(=O)CN1CCCOC1=O)C(C)(C)C +Cc1ccccc1CC(C)(C)NC(=O)c1nc2ccccc2c(=O)[nH]1 +Cc1c(C(=O)OCC(N)=O)oc2c1C(=O)CC(C)(C)C2 +Cc1nnc(SCc2cc(-c3ccccc3)no2)n(N)c1=O +COc1ccc(C(O)c2ccc3c(c2)OCCO3)cc1 +Cn1ccnc1CN1CCCN(C(=O)CCc2ccco2)CC1 +NC(=O)C(c1ccccc1)N1CCN(C(=O)NCc2ccco2)CC1 +CC(C)NC(=O)N1CC2CC(C(=O)Nc3ccccc3)C(C1)O2 +CCNS(=O)(=O)c1cccc(C(=O)NCC2CCCC(C)C2)c1 +COC(=O)c1n[nH]c2ccc(NC(=O)COC3CCCCC3)cc12 +CCOC(=O)N1CCN(C(C)C(=O)c2cccs2)CC1 +N#Cc1cccnc1NCc1ccc(OC(F)F)cc1 +CCN1CCc2nc(NC(=O)c3c(F)cccc3F)sc2C1 +CC(=O)c1cccc(NCCC(=O)c2ccccc2)c1 +CN1C(=O)CC(C(=O)NCC(=O)C(C)(C)C)C1c1cccs1 +COc1cc(C)sc1C(=O)N1CCCC(C(N)=O)C1 +COCCNC(=O)c1sccc1-c1ccc(C)cc1 +CC(C)N(C)C(=O)c1csc(-c2ccccc2)n1 +CC1CCCN(C(=O)Cn2cnc3ccc(Cl)cc3c2=O)C1 +O=c1n(Cc2coc(-c3ccccc3)n2)nnn1-c1cccs1 +N#CCCN(CCN1CCOCC1)C(=O)c1ccc(C#N)cc1 +CN(C(=O)NCc1ccnc(OC(C)(C)C)c1)C1CCC(CO)CC1 +CC(C)(C)OC(=O)NCc1cn(-c2ccccc2)nn1 +NC(=O)c1ccc(NC(=O)c2cc(F)cc3[nH]cnc23)cc1 +Cc1ccc(OCC(=O)Nc2cc3c(cc2N)OCO3)cc1 +COC(=O)CCSc1nnc(Nc2cccc(F)c2)s1 +Cc1ccc(NC(=O)Cn2ncc3c([nH]c4ccccc43)c2=O)nc1 +Cc1cccc(CNC(=O)C2CC(=O)N(C(C)c3ccccc3)C2)c1 +Clc1ccc(C2=Nc3ncnn3C(c3ccco3)C2)cc1 +O=C(NCCCOc1ccccc1)c1n[nH]c(=O)[nH]1 +Cc1ccc(Cl)cc1NC(=O)c1cscn1 +O=C(COCC1CC1)Nc1nc2ccc(Cl)cc2s1 +Cn1ccc(C(=O)Nc2nc(-c3ccccc3)cs2)n1 +COc1ncc(C)cc1NC(=O)c1cn(C)nc1-c1cccs1 +CC1(C(=O)N2CCCC(n3cncn3)C2)Cc2ccccc2C(=O)O1 +CC(C)C(C)n1nccc1NC(=O)C1CCN(c2ncccn2)CC1 +O=C(c1ccc(CS(=O)c2ncccc2Cl)cc1)N1CCCC1 +CC(C)CNC(=O)c1cc(=O)c(OCc2ccccc2Cl)c[nH]1 +COc1cccc(C(=O)CNC(=O)Cc2cccs2)c1 +Cc1cc(C)n(CC(=O)Nc2ccc(F)c(N)c2)n1 +Cc1ccc2c(c1)OCCN2C(=O)Cc1cccc(OCC#N)c1 +O=C(NC1CCN(C(=O)NC2CC2)CC1)c1ccccc1 +COCCOCC(=O)Nc1cccc(C(=O)N2CCCCC2)c1 +CCOC(=O)c1cccc2[nH]c(=O)n(-c3cccc(N)c3)c12 +COc1ccccc1C(C)NC(=O)NCC1CCC1 +CCc1noc(CC)c1CC(=O)NCc1nc2ccc(F)cc2[nH]1 +CCC(CC)CNc1cccc(S(C)(=O)=O)c1 +CN(C)C(=O)C1CCN(c2nc3ccccc3s2)CC1 +CC(C)CCNc1ccc(S(=O)(=O)N2CCOCC2)cn1 +Cc1cc(C)c2c(c1)CCNC2c1ccc(N)cc1 +O=C1CN(C(=O)CNc2ccc(-n3cccn3)c(Cl)c2)CCN1 +O=C1CCC(C(=O)N2CCN(CC(=O)N3CCCCCC3)CC2)N1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)NCC1CCCCC1 +C=CCCOC(C)C(=O)Nc1cc(C#N)cn1C(C)(C)C +N#Cc1cc2c(nc1SCc1cc(=O)[nH]c(=O)[nH]1)CCCCC2 +O=c1ccc(-c2ccc(S(=O)(=O)NCc3ccccc3)s2)n[nH]1 +CCCCn1nnnc1CN1CCc2cnc(C)nc2C1 +COC(=O)C(NC(C)C)c1cc(F)c(F)c(F)c1 +O=C(Nc1cccc(-n2cnnn2)c1)c1ccn(-c2cccc(F)c2)n1 +CN1CC(c2ccccc2)C2(CCN(c3ccc(C#N)cn3)C2)C1=O +O=c1[nH]c2ccc(F)cc2c(=O)n1-c1ccc(Cl)cc1Cl +CCOC(=O)NCCC(=O)NC1CC(C)(C)Cc2oc(C)cc21 +Cc1cc(NC(=O)C2CCN(C(=O)CC3CCCC3)CC2)no1 +COc1cc(OC)c(NC(=O)c2ccc(C#N)cc2)cc1Cl +CN(Cc1cccnc1)S(=O)(=O)c1ccccc1C#N +CC(C)(C)c1ccnc(CCc2cccc(N)c2)n1 +CCOC(=O)Nc1ccc2c(c1)CN(C(=O)c1cccs1)CC2 +N#Cc1ccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)cc1 +O=C(Cn1ccccc1=O)NC(c1ccccc1)c1ccccn1 +COc1c(Cl)cccc1NC(=O)c1ccccc1OCC(N)=O +N#CC(NS(=O)(=O)c1ccccc1)c1ccccn1 +CCCC1CN(C(=O)C2CCC(=O)NC2)CCO1 +O=C(NCc1cccc(F)c1)N1CCC(Oc2ccccc2)CC1 +CC(=O)Nc1nc(C(=O)NC(C)(C)c2nc(C)c(C)s2)cs1 +CSc1c(OC2CC2)cccc1C(=O)N(C)C +CC(Sc1ncnc2c1cnn2C)c1ccccc1 +Cc1nc(C)c(C(=O)Nc2ccc(Oc3cccnc3)nc2)s1 +Cc1[nH]c2ccccc2c1C(=O)C(C)OC(=O)c1cccc(O)c1 +Cc1ccc(C)c(NC(=O)C2CNc3ccccc3O2)c1 +O=C(Nc1ncn(CC(=O)N2CCCCCC2)n1)c1ccoc1 +COCCn1ccc2c(NC(=O)Cn3ccc4ccccc43)cccc21 +Cc1nnc(-c2nc3c([nH]2)CC(c2ccc(F)cc2)CNC3=O)o1 +O=C(NC1CC1)c1ccc(-c2cnn(Cc3ccccc3)c2)nc1 +COc1ccc(-c2ccc(N)c(=O)n2CC(C)C)cc1 +CCOCC1CN(Cc2ccc(C)o2)Cc2nn(CC3CC3)cc21 +Cc1csc(N(C)C(=O)CCC=Cc2ccccc2)n1 +CCN(CC)S(=O)(=O)NC1(c2ccc(Br)cc2)CC1 +CCn1c(=O)c2c(nc3n(Cc4ccco4)c(C)c(C)n23)n(C)c1=O +Cc1nc2nc(C)c(C(=O)N3CCN(c4ccccc4)CC3)cn2n1 +CCCN(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCCN(CCC)S(=O)(=O)c1ccc(N)cc1 +N#Cc1ccccc1CSc1nc(N)cc(N)n1 +CCC(C)Nc1nc(CN2CCOCC2)nc2sc3c(c12)CCC3 +c1ccc(OCc2ccc(CN3CCOCC3)cc2)cc1 +Cn1cc(CCNC(=O)N2CCc3ccc(Cl)cc3C2)cn1 +COc1ccc(N2CCN(CC(=O)Nc3ccc(F)cc3)C2=O)cc1 +Cc1noc(C)c1C(C)NC(=O)N(C)Cc1ccccc1F +FC(F)(F)c1nc(NCc2nnc3ccccn23)c2ccccc2n1 +Cc1cc(C)n(C2CCCN(C(=O)c3cccn4ccnc34)C2)n1 +Cn1c(=NC(=O)c2ccncc2F)[nH]c2cc(Cl)ccc21 +COCCOC(=O)c1c(C)[nH]c(C(=O)Nc2c(C)noc2C)c1C +CN(C)c1ccc(C(=O)N2CCCC3(CCCC(=O)N3C)C2)cc1 +Cc1occc1C(=O)NCc1ccccc1COC(C)C +O=C(CNC(=O)c1cccs1)Nc1ccccc1Br +O=C(Nc1ccc2c(c1)OCO2)c1ccc(OCC2CCCO2)cc1 +CCn1cc(C(=O)NCc2ccc(S(=O)(=O)NC)cc2)cn1 +CNC(=O)Cn1c(CO)cnc1SCc1ccccc1C +COc1cc(OC)c(NS(=O)(=O)N(C)C)cc1Cl +CCc1cc(=O)n2c(n1)SCC2CC(=O)NCC(C)C +CC(C)NC(=O)N1CCN(c2ccc(F)cc2F)C(=O)C1C +CC1CCC(NC(=O)c2cccc(S(=O)(=O)NCCC#N)c2)CC1 +Cc1n[nH]c(C)c1N1CCN(C(=O)COc2ccc(Cl)cc2)CC1 +Cc1ccc(NC(=O)CCNC(=O)c2c(C)cc(C)n(C)c2=O)cc1 +CCn1c(-c2cc(OC)c(OC)c(OC)c2)n[nH]c1=O +Cc1csc(CCNS(=O)(=O)c2ccc(Cl)cc2)n1 +Cn1cnc2ncnc(NCc3ccccc3Cl)c21 +CC(CC(=O)Nc1ccc(OC(F)(F)F)cc1)n1ccnc1 +COc1ccccc1CC(=O)N(C(C)C)C1CCC1 +CC(C)(C)C(=O)NCCCn1c(=O)oc2ccccc21 +COc1ccc(F)cc1-c1cnc(-n2cnnc2)cc1C +CC(C)CC(=O)c1c[nH]c(C(=O)NCC2CCCO2)c1 +Cc1cc(NC(=O)CSc2ccccc2F)ccc1C(=O)N(C)C +CC(C)CNC(=O)CCC(=O)c1ccc(F)c(F)c1 +O=C(Nc1ccccc1-n1cccn1)c1ccnc(OC2CCC2)c1 +COc1cccc(C(=O)Nc2ccc(Cl)c(NC(C)=O)c2)c1F +CC1CN(C(=O)CCn2c(=O)n(C)c3ccccc32)C(C)CO1 +COc1ncccc1CNC(=O)NC1c2ccccc2CC1O +Cc1ncsc1C(=O)Nc1cccc(OCC(F)F)n1 +O=C(Nc1cccc(C(=O)N2CCOCC2)c1)N1CCCCCC1 +Cc1nnc(SC(C)c2nnc(-c3ccccc3)o2)n1N +CCN(C(=O)CNc1cc(OC)ccc1NC(C)=O)c1ccccc1 +O=S(=O)(CC1CSc2ncnn21)c1ccc2ccccc2c1 +CC(C)(C)CCNC(=O)N1CCC(NC(=O)c2ccsc2)CC1 +Cc1nc(NCCCn2ccnc2)cc(-c2ccccc2F)n1 +O=C(COc1ccc(=O)n(-c2ccccc2)n1)N1CCCCCC1 +CC(C)OCCC(=O)Nc1nnc(-c2ccccc2Cl)s1 +CC1CCc2sc(C(=O)OCC(=O)NCc3cccs3)cc2C1 +Cc1nn(-c2ccccc2)c(C)c1NC(=O)CNc1ccc(F)cc1 +NC(=O)c1ccc(N2CCCC2)c(NC(=O)Cc2ccc(F)cc2)c1 +CCOc1ncnc(NC23CC4CC(CC(C4)C2)C3)c1N +CCCCC(=O)NCCc1cc(Cl)c2c(c1)OCCO2 +CCOc1ccc(S(=O)(=O)N(C)C2CCCCC2O)cc1 +O=S(=O)(c1cc(-c2nnc(C3CCCC3)o2)co1)N1CCCC1 +Cn1cc(NC(=O)CCCC(=O)Nc2cnn(C)c2)cn1 +O=C(Cn1ccnc1)NC(c1ccccc1)C1CC1 +Cc1n[nH]c(C)c1C1CCCCCN1C(=O)Nc1ccccc1 +NC(=O)c1nn(-c2cccc(Br)c2)c2c1CNCC2 +COCCN(C)C(=O)NCC1(c2ccc(F)cc2F)CC1 +Nc1cccc(S(=O)(=O)N2CCNC(=O)C2)c1 +CC(C)C1OCCC1CNC(=O)c1cccnc1OCC(F)F +Cc1nn(C)c2ncc(C(=O)N3CC(C)Sc4ccccc43)cc12 +N#CCCCn1c(CCc2ccccc2)nc2ccccc21 +CCn1c(C)c(C)n2c3c(=O)n(CC(C)C)c(=O)n(C)c3nc12 +CC(=O)c1ccc(NC(=O)N2CCc3nc4ncccc4cc3C2)cc1 +CCn1cc(C(=O)Nc2cc(-c3ccoc3)nn2-c2ccccc2)cn1 +CC(Nc1ccc2nnnn2n1)c1noc(-c2ccc(Cl)cc2)n1 +CCc1nn2c(CNC(=O)Cc3ccccc3C)c(C)nc2s1 +CC(C)(C)C(C#N)NC(=O)C1COc2ccc(F)cc2C1 +CCNc1nc2sc3c(c2c(=O)n1CC)CCCC3 +COc1cc(F)c2c(c1)C(c1cc(O)cc(O)c1)NCC2 +CCc1csc(-c2cn(CC(=O)Nc3cccc(C)c3C)cn2)n1 +Cc1ccc(C(=O)OCC(=O)NCc2cccs2)cc1C +COCC(C)CNC(=O)c1cnc(N)c(Cl)c1 +CN(C)C(=O)CCC(=O)c1ccc(Br)cc1 +CN(C)c1ncnc(NCc2ccc(F)cc2)c1N +O=S(=O)(Nc1ccccc1)c1ccccc1Cl +Nc1cc(-c2ccc3nc(-c4ccccc4)[nH]c3c2)no1 +COCCNC(=O)CNc1cccc2ccccc12 +O=C(OCC1CC(=O)N(C2CC2)C1)c1ccc(F)cc1 +CCCC(=O)N1CCN(c2ccnc(N3CCCC3)n2)CC1 +CN1C(=O)C(C)(C)c2cc(C(O)c3cccs3)ccc21 +CCc1ccc(CNC(=O)Cn2c(C)c(C)sc2=O)s1 +COC(=O)CC(C)(C)CC(=O)Nc1cccc2[nH]cnc12 +COCC12CCCOC1CCN(C(=O)c1cc3ccccc3s1)C2 +Cc1oc(-c2ccccc2)nc1Cn1c(-c2cccnc2)noc1=O +O=C(CNC(=O)c1ccc(F)cc1)NCc1ccccc1Cl +Cn1cc(C(=O)Nc2ccc(CC#N)cc2)c(C(C)(C)C)n1 +CC1=C(C(=O)NCc2ccccc2)C(c2ccccc2)n2nnnc2N1 +COc1ccc(C(NC(=O)NC2(C)CCOC2)C2CCOCC2)cc1 +CC(=O)c1cccc(NC(=O)Cn2cnc3oc(C)c(C)c3c2=O)c1 +CN(Cc1cccc(Br)c1)Cc1nccn1C(F)F +CCC(Oc1cccc(C(C)=O)c1)C(=O)OC(C)C +CC(C)c1ccccc1OCCn1c(=O)oc2cc(N)ccc21 +Cc1noc(CN(C(=O)OC(C)(C)C)c2ccccc2)n1 +CCCc1nc(N2CCc3[nH]nc(CC)c3C2)c2cnn(C)c2n1 +COc1ccc(CCn2cnc3sc(C)c(C)c3c2=O)cc1 +CCOC(=O)C(C)(C)n1cc(CO)c2cc(F)ccc21 +Cc1ccc2nc(COc3ccccc3C#N)cn2c1 +CCCOc1ccc(-c2nn3cnnc3n(CCO)c2=O)cc1 +CCC(C)C(C)NC(=O)NCc1ccc2c(c1)OCO2 +CCOc1ccc(C#N)cc1NC(=O)CCC(C)C +Cc1cc(C)n(CCCNC(=O)c2nn3cccnc3c2Cl)n1 +COc1ccc(OC)c(C(O)Cc2ccc(F)cc2)c1 +Cc1ccc(NC(=O)CCC(=O)Nc2nccs2)nc1 +CCC(C)NC(=O)C(C)NC(=O)c1csnn1 +COC(=O)c1ccc(Cl)cc1OS(=O)(=O)N(C)C +COc1ccccc1C(=O)Nc1ccc2c(c1)OCC(=O)N2 +CC(C)C(Sc1nnc(C(C)(C)C)n1N)C(=O)N1CCOCC1 +CCNC(=O)CN(C)S(=O)(=O)c1cccnc1 +CC(C)(C)OC(=O)N1CCCC1C(=O)NCc1ccccc1Cl +COc1cccc(CNC(=O)c2ccccc2OC)c1 +O=C(Cc1ccc[nH]1)NC1CCN(CC(F)(F)F)C1 +CCc1ccccc1NC(=O)CNc1nccn2cnnc12 +O=C(OCCNc1cccnn1)C1CCCCN1C(=O)c1ccco1 +CCCNC(=O)c1ccccc1S(=O)(=O)CC +NC(=O)C(Nc1cccc(CN2CCCCC2=O)c1)c1ccccc1 +COc1ccc(-c2nnn(-c3ccccc3C)c2N)cc1 +COCCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(C)s1 +Nc1c(F)cccc1C(=O)N1CCC(n2cccn2)CC1 +O=C(CNC(=O)Cc1ccc2c(c1)CCC2)NCC(F)(F)F +O=C(NCc1ccccc1)N1CCC(O)C1Cc1cccnc1 +O=C(c1ccncn1)N1CC2CC(c3nnc(C4CC4)o3)OC2C1 +CN(C)c1nccc(CN2CCN(c3ccc(C(N)=O)cc3)CC2)n1 +Cc1ccccc1S(=O)(=O)Cc1cccc(C(N)=O)c1 +O=C(COc1ccc(Cl)cc1)NCc1ccccc1 +O=c1c2ccsc2ccn1Cc1nnc(-c2ccccc2Cl)o1 +CC(=O)c1ccc(NC(=O)CSc2cccs2)cc1 +Cc1nc(NC(=O)Nc2ccccc2)sc1C(=O)NC1CCCC1 +Cc1cccc(C(=O)NCC(C)(C)c2ccncc2)c1 +Cn1c(SCC(=O)N2CCCCC2)nc2sccc2c1=O +CNC(=O)CSc1ccc(S(C)(=O)=O)cc1 +Cc1cc(C)c(CNC(=O)NCCCOc2ccccc2F)c(=O)[nH]1 +CC(=O)c1c(C)[nH]c(C2=Nn3c(nnc3-c3ccco3)SC2)c1C +Cc1ccc(Nc2nn[nH]c2C(=O)NCc2ccc(F)cc2)cc1F +O=C1CN(CCS(=O)c2ccccc2)CCN1 +Cc1ccccc1-n1cc(C(=O)n2ncc(C#N)c2N)cn1 +O=C(Nc1ccccc1O)C1CCN(C2CCOC2=O)CC1 +COc1ccc(OC)c(CC2C(=O)Nc3ccc(Cl)cc32)c1 +O=C(NCC1CCN(C(=O)C2CCCC2)CC1)C1CCCC1 +CS(=O)(=O)NCc1ccc(C(=O)NC2CC2)cc1 +CC(=O)Nc1cc(C(=O)Nc2cc(C)ns2)cc(C(F)(F)F)c1 +CC(c1ccccc1)N(C)C(=O)c1c[nH]c2ccccc2c1=O +CCc1ccc(-c2nc(CC(=O)NC3CCCC3)no2)o1 +CCC(CC)C(=O)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +O=C(CSc1nnc(N2CCCC2)s1)Nc1ccccc1 +Cc1ccc(-c2csc(-c3cnccn3)n2)cc1C +CCCOc1ccc(C(=O)Nc2nc(C)c(C(C)=O)s2)cc1 +CCN(CC)C(=O)N1CCC(C(=O)N2CCOCC2C2CC2)CC1 +COC(=O)c1ccc(NC(=O)COC(=O)c2cccc(C)c2N)cc1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)CCc1ccco1 +CN(C)c1ccc(-c2nc3sccc3c(=O)[nH]2)cc1 +CCc1nn(-c2nc3c(C)cccc3s2)c(N)c1C#N +Cc1cc(C)cc(OCCCCN2CCOCC2)c1 +COc1cc(OC)cc(C(=O)N2CCC(O)(C(F)(F)F)CC2)c1 +Cn1cc(Br)cc1C(=O)N1CCC(C)(C)CC1 +CC1Cc2ccccc2N1S(=O)(=O)c1ccc(N)cn1 +COC(=O)c1ccc(F)nc1NC(=O)OC(C)(C)C +Cc1ccc(C(=O)NCC(C)C)cc1S(=O)(=O)N1CCCCC1 +COc1cc(C)ccc1OCC(=O)N(C)Cc1cccnc1 +CNC(=O)c1cccc(NC(=O)NC(C)(C)CO)c1C +CCOc1cc(CNc2nnnn2C)cc(Br)c1OC +NC(=O)CCCNC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +COc1ccccc1OC(=O)c1ccc2c(c1)OCO2 +Cc1nn(C)c(C)c1CCC(=O)N(Cc1ccco1)C(C)C(C)C +CN(Cc1ccc(OC(F)F)cc1)C(=O)c1c(F)cccc1F +Nc1ccc(C(O)CSc2ccc(F)c(F)c2)cc1 +COc1cc(C(C)NCCN2CCOCC2)ccc1O +O=C(CCN1CCCC1=O)Nc1ccc(Nc2ccccc2)cc1 +Nc1csc(S(=O)(=O)N=c2[nH]c(C3CC3)cs2)c1 +COC(=O)c1cc(C(=O)Nc2cnn(C)c2C(N)=O)n(C)n1 +O=C(Cc1ccc2c(c1)OCO2)Nc1ccc(F)cc1F +COc1ccc(O)c(C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1 +CCCn1c(=O)n(CC(=O)Nc2ccncc2)c2ccccc21 +Cc1nc(COc2ccc(F)cc2)[nH]c(=O)c1CCO +O=S(=O)(NC1CCC(O)CC1)c1ccc2c(c1)CCO2 +CCCn1c(-c2ccccc2OC)ccc(CC#N)c1=O +O=C(c1cccc2ccnn12)N1CCCC1c1nccs1 +COCCOc1ccccc1C(=O)NCc1cccc(C)n1 +Cc1cc(C)c(S(=O)(=O)NCCCc2nc(C)cs2)c(C)c1 +COC(=O)C1CC(O)CN1Cc1ccc(-n2cncn2)cc1 +Cc1ccccc1CNC(=O)CN1C(=O)CSc2ccccc21 +CC1Cc2ccccc2N1S(=O)(=O)c1cnn(C)c1 +CN(CC(F)(F)F)C(=O)c1cc2c(F)cccc2[nH]1 +Cn1cc(Br)cc1C(=O)Nc1ccc(-c2cnco2)cc1 +CNC(=O)Cn1ccnc1-c1ccc(F)c(F)c1F +CNc1cccc2c(OCc3cccnc3)ncc(C)c12 +CC(C)Sc1ncccc1C(=O)NCC(=O)N(C)C +Cc1ccc(C(=O)N(C)C(C#N)c2ccc3c(c2)OCO3)cc1 +COc1cc(NC(=O)CCC2CCCC2)cc(-n2cnnn2)c1 +NC(=O)NCCC(=O)N1CCOC(Cc2cccc(F)c2)C1 +CC(=O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 +COC(=O)c1sccc1NC(=O)Cc1cccc(C)c1 +CCCn1cc(NC(=O)c2csnn2)ccc1=O +CN1CCC(NC(=O)c2ccc(CNC(=O)C3CCCC3)cc2)C1=O +CCOCc1ccc(NC(=O)c2scnc2C2CC2)cc1 +Cc1nn(Cc2ccc(C(=O)N(C)CC3CC3)cc2)c(C)c1Cl +CN(C(=O)CSc1ncn[nH]1)C1(C#N)CCCCC1 +COc1cccc(CNC(=O)COC(=O)c2cccc(C)c2)c1 +Cc1ccc(C(=O)N(C)CCc2noc(-c3cccc(C)c3)n2)cc1 +COc1cc(CNc2cccc(-n3nnnc3C)c2)cc(OC)c1 +Oc1ccccc1N1CCN(Cc2ccno2)CC1 +CC1CCCCC1OCCNC(=O)NC1C=CC(CO)C1 +COc1cccc(C(=O)NCC(C)Oc2ccc(F)cc2)c1F +CCc1nnc(NC(=O)NCc2ccc(OC(C)C)cc2)s1 +CCOc1ccc(OCCc2nc3c(s2)CCN3)cc1 +Cc1oc(-c2ccccc2F)nc1Cn1ncn2cccc2c1=O +Nc1cc(-c2cccs2)nn(CC(=O)Nc2ccccc2F)c1=O +CCCNC(=O)NCc1ccnc(OC2CCCC2)c1 +O=C(c1ccc(=O)[nH]c1)N1CCN(Cc2cccc(Cl)c2)CC1 +COCCC1CCN(C(=O)C2COc3ccccc3O2)CC1 +CCN(CC)C(=O)c1cnn(-c2ccccc2)c1N +Cc1cc2c(cc1NC(=O)CCc1cc(OC(C)C)no1)OCCO2 +CCN1CCOc2ccc(NC(=O)CC(C)C)cc2C1=O +CCCCCCNC(=O)c1c(C)c(C)nn(C)c1=O +O=C(OCCc1cccnc1)c1cccc(-n2cccn2)n1 +Cc1ccc(C)c(Cn2nc(C(F)(F)F)n(C)c2=O)c1 +COCc1nc2n(n1)C(c1cc(OC)ccc1OC)CC(C)N2 +COc1ccc(CN(C)C(=O)NC2CCCCC2C)cc1O +CC(C)c1cc(C(=O)N2CCC(OCc3ccccc3F)CC2)n[nH]1 +NC(=O)CSc1ncc(-c2cccc(Br)c2)o1 +COc1cccc2c1N(S(=O)(=O)N(C)C)CCC2 +COc1ccc(CCNC(=O)c2nc(-c3cccnc3)no2)cc1 +Cc1cc(C)cc(OCCNC(=O)NCc2cnc(C)s2)c1 +Cc1ccc(C)c(NC(=O)C(C)n2ncc(-c3ccccc3)nc2=O)c1 +CCCNS(=O)(=O)c1cc(N)c2c(c1)CC(=O)N2C +COc1ccc(CNC(=O)N2CCCCCC2)cn1 +CCN(CC)C(=O)CCNC(=O)N(C)Cc1csc(C)n1 +CC1CCC(C(N)=O)CN1C(=O)c1cc(-c2cccs2)n[nH]1 +NC(=O)C1CN(CC(=O)Nc2cccc(Cl)c2)c2ccccc2O1 +CCc1nnnn1-c1ccccc1NC(=O)Cc1c[nH]c2ccccc12 +O=C1NCC2CN(Cc3ccc(Cl)cc3)CCN2C1=O +N#Cc1cccc(CN2CCOC(c3ccccc3)C2)c1 +COc1ccccc1C(=O)NC1CCN(C(=O)OC(C)(C)C)C1 +COc1ccc(CNC(=O)c2cc3ccccc3s2)cc1OC +CC(C)CN(C)S(=O)(=O)c1ccccc1S(N)(=O)=O +CCc1nnc(-c2ccc(S(=O)(=O)NCc3ccc(C)cc3)o2)o1 +C#CCn1cc(CN(C)C(=O)Nc2c(C)noc2CC)cn1 +Cc1noc(C)c1CNC(=O)Nc1cccnc1Oc1ccccc1 +COc1ccc(CNC(=O)c2ccc3[nH]cnc3c2)cc1F +COc1cccc(C(=O)Nc2ccc(CN3CCCC3=O)cc2)c1 +Cc1cccc(C)c1OCC(O)CSc1nccn1C +C#CCOc1ccc(C2NC(=O)c3ccccc3N2C)cc1 +CC(O)CNS(=O)(=O)c1ccc(OC(F)F)c(Cl)c1 +Cc1nc(-c2ccccc2)sc1NC(=O)NC1C=CC(CO)C1 +COCCSc1nc2ccccc2n1CCOC +O=C1C(Nc2nccn3cnnc23)CCN1c1cccc(Cl)c1 +Cc1ccccc1OCCCC(=O)Nc1cccn(C)c1=O +O=C(OCCOc1cccnc1)c1cccc2ncccc12 +CC(=O)Nc1ccc(C(=O)NC2CCOCC2)cc1 +CCc1cc(C(=O)Nc2ccc3c(c2)OCO3)no1 +CN(C(=O)Cc1ccc[nH]1)C1C2CCOC2C1(C)C +CCS(=O)(=O)Nc1ccc(C(=O)Nc2c(C)cccc2C)cc1 +CC(C)(C)OC(=O)CNC(=O)C1(C)CC1(Cl)Cl +O=C(c1ccccc1NCc1nnc(C2CCC2)o1)N1CCCCC1 +COC(=O)Cc1ccc(OCC(=O)Nc2ccc(C)cc2)cc1 +CCC1(CC)Oc2ccc(S(=O)(=O)NC)cc2NC1=O +CN(C)C(=O)N1CC(C(=O)NCc2ccco2)CC2OCCC21 +O=C(Nc1cnc2sccn2c1=O)C1CCCC1 +Cc1ccc2ncc(C(=O)Nc3ccc(CN4CCCC4=O)cc3)n2c1 +COc1ccccc1-n1ccnc1SCC(=O)NC1CCCC1 +O=C(NCc1ccccc1)c1cccc(NC(=O)C2CCCC2)c1 +Cc1nc(NCCNC(=O)c2ccccc2C)cc(N(C)C)n1 +Cc1oc2cc(C#N)c(C#N)cc2c1C(O)c1cccs1 +Cc1nc(C2Nc3ccccc3C(=O)N2Cc2cccnc2)cs1 +O=C(CC1CCCC1)N1CCN(C(=O)c2cc3ccccc3o2)CC1 +CCOc1cc(C)c(-c2cc(N)nn2C)cc1Cl +CNc1cc(C(=O)NCc2ccccc2C)ccn1 +CN(CCC#N)C(=O)Cc1ccc2ccccc2c1 +C=CCCCN(C)C(=O)c1ccc(N2CCCS2(=O)=O)cc1 +OCc1cc(-c2ccccc2OCc2ccccc2)n[nH]1 +COc1ccc(C2CC(=O)c3cnn(-c4nc(C)cc(C)n4)c3C2)cc1 +CCn1c(CCNC(=O)c2ccc(C#N)cc2)nc2cccnc21 +Cc1nc(CNC(=O)c2ccn(-c3ccccc3Cl)n2)cs1 +CCCN(CCC)C(=O)c1c(C)nn(C(C)(C)C)c1C +COC(=O)c1ccccc1C1=NCCc2cc(OC)c(OC)cc21 +N#Cc1ccc(C(=O)NCc2cc(-c3ccc4c(c3)OCO4)on2)cc1 +Cc1cc(C(=O)NC2CCN(S(=O)(=O)C(F)(F)F)CC2)no1 +Cc1nn(C)c2nc(C(C)C)cc(C(=O)Nc3cccc4[nH]ccc34)c12 +CCc1nc(NC2CCCCCC2)c(N)c(OC)n1 +Cc1nc2c3c4c(sc3nc(N3CCOCC3)n2n1)CCC(C)C4 +COC(=O)c1ccc2c(c1)nc(C#N)n2-c1ccncc1 +Cc1nn(C)c(C)c1CNc1cccc(COCc2ccco2)c1 +COc1ccc(N(C)C(=O)c2cc(C)no2)cc1OC +O=C1NCCCC1C(=O)N1CCC2(CC1)Nc1ccccc1NC2=O +COc1ccccc1CCNC(=O)c1scnc1C1CC1 +COc1ccc(-n2nncc2-c2cc(OC)c(OC)c(OC)c2)cc1 +O=C(NCC1CCCO1)N1CCCn2nc(-c3cccs3)cc2C1 +Nc1ccccc1NC(=O)c1ccc(F)cc1Cl +CC(O)c1c(F)cccc1N(C)c1ccccc1F +CCc1nc(CN2CCN(Cc3cnc4c(C)cccn34)CC2)no1 +CCC(=O)N1CCCN(C(=O)Nc2ccccc2OC(F)F)CC1 +COc1cccc(S(=O)(=O)CC(=O)N(C)CC2CC2)c1 +CCS(=O)(=O)N1CCC2(CCC(=O)N2Cc2cccnc2)CC1 +O=C(NC1CCN(C(=O)c2ccoc2)CC1)c1cc(C2CC2)[nH]n1 +Cc1c(Br)ccc(S(N)(=O)=O)c1C +CNS(=O)(=O)CC(=O)N(C(C)C)C1CCCC1 +CNC(=O)c1nc(Cn2ccc3ncccc3c2=O)no1 +Cc1c(NCC(=O)NCc2ccco2)cccc1NC(=O)C1CC1 +O=C(NC1CC1c1c(F)cccc1F)C1CCCN(C(=O)C2CC2)C1 +OC1CCCCC1N1CCOC(c2cccc(OC(F)F)c2)C1 +Oc1ccc(NC2CCN(CC(F)(F)F)CC2)cc1 +Cc1cccc(C(=O)N2CCN(Cc3cc4ccccn4n3)CC2)c1 +O=C(c1cncc(-c2ccsc2)c1)N1CCc2ncccc2C1 +Cc1cn(CC(=O)NCC2COc3ccccc3C2)c(=O)[nH]c1=O +O=S(=O)(Cc1ccccc1)NCC1(c2ccc(F)cc2)CC1 +O=C(CCn1ccccc1=O)N1CCCC(CO)C1 +CC(C)NC(=O)c1nc(-c2cn(-c3ccc(F)cc3)nn2)no1 +Cc1occc1CN(C)S(=O)(=O)c1cccc(Cl)c1Cl +Cc1cc(C)n(S(=O)(=O)c2ccc(C(C)(C)C)cc2)n1 +COc1ccc(C)cc1NC(=O)c1ccccc1OCC(N)=O +CCCNC(=O)c1ccc(NC(=O)N(C)C(C)c2ccco2)cc1 +O=C(CCC1CCCC1)Nc1nnc(C2CCC2)s1 +Cc1cc(NC(=O)NCCc2ccccn2)ccc1Br +CC(=O)Nc1cccc(NCCC(O)c2ccc(C)c(C)c2)c1 +CCC(C(=O)N1CCCN(S(C)(=O)=O)CC1)c1ccccc1 +CC(C)c1ccc(C2CCCN2C(=O)CCCCNC(N)=O)cc1 +Cc1nc(C)c(-c2csc(-c3cccc(N)c3)n2)s1 +C#CCOc1ccc(C(=O)N2CCCC2CO)cc1 +CCCCC(=O)Nc1ccc2[nH]c(-c3ccncc3)nc2c1 +COc1cccc(C(=O)N2CCCC(CC(N)=O)C2)c1F +CCc1nc(C2CCCN(C(=O)c3cc(C)n(C(C)C)c3C)C2)no1 +CCc1nnsc1C(=O)NCC1CCC(CC)CC1 +CN(Cc1cccnc1)C(=O)C1CCC(=O)N(C2CCCCCC2)C1 +COc1cc(OC)cc(C(=O)N(C)C(C)c2ccccc2OC)c1 +CCNC(=O)c1cc(NC(=O)Cc2ccn[nH]2)nc2ccccc12 +O=C(Cn1cc(C2CC2)nn1)NC(c1cc(F)ccc1F)C1CC1 +CCC(CC)NC(=O)c1ccc2c(c1)N(S(C)(=O)=O)CC2 +COCc1ccc(CN2CCOC(CC(=O)OC)C2)cc1 +Cc1cc(C(=O)NCCC(=O)N2CCN(C)CC2)n(C)n1 +CC(C)(CO)NC(C#N)c1cccc(Cl)c1Cl +Cc1noc(COCC(=O)N(C2CC2)C(C)c2ccc(Cl)cc2)n1 +COc1ccc(-c2nc(COc3cccc(F)c3)nn2C)o1 +O=C(CCc1ccccn1)Nc1nnc2ccccn12 +CC(C)(C#N)NC(=O)CCc1nc2ccccc2[nH]c1=O +O=C(Nc1ccc(C(F)(F)F)cc1)c1ncc[nH]1 +Cc1cc(C)n(CC(C)CNC(=O)COc2ccccc2)n1 +Cc1ccccc1-n1cc(-c2nc(-c3ccc(C#N)cn3)no2)cn1 +COC(=O)C(c1ccccc1F)N1CCn2c(nn(C)c2=O)C1 +CCc1nc(CC(=O)NCc2nc(C)c(C)o2)cs1 +Nc1ccc(-c2nc3ccc(F)c(F)c3n2N)cc1 +Cc1cc(C)n(CC(=O)Nc2ncc(C)s2)n1 +CN(Cc1cc(N)ccc1Cl)C(=O)C1CCCC1 +Cc1cc(C(=O)Cn2nnc(-c3cccc(F)c3)n2)c(C)n1C +CCOc1cccc2sc(NCc3ccccn3)nc12 +CC1CCCN(C(=O)c2ccc(S(=O)C(C)C)cc2)C1 +Cc1ccc2ncc(C(=O)NCCC(=O)NC(C)C)n2c1 +Cc1cc2nc(CN3CCOCC3)n(CC#N)c2cc1C +Cn1c(SCC(F)(F)F)nnc1-c1ccccc1 +CC(C)(C)C(=O)N1CCN(C(=O)NCC(F)(F)F)CC1 +CC(C)C(=O)NCc1c(-c2ccc(Cl)cc2)nc2n1CCS2 +CCNC(=O)N1CCCC(c2noc(CC)n2)C1 +O=C(NCc1cn2cc(Cl)ccc2n1)Nc1cc(F)cc(F)c1 +COc1ccccc1C1CC1C(=O)N1CCCC1Cn1cccn1 +COc1ccc(N(C)C(=O)C2(c3ccccc3)CC2)cn1 +CC(O)c1nc2cc(F)ccc2n1Cc1cccc(N)c1 +O=C(CCn1cnc2sccc2c1=O)Nc1nc2ccccc2[nH]1 +CS(=O)c1ccc(CNC(=O)Cc2ccc[nH]2)cc1 +COc1ccc(Cl)cc1NC(=O)c1ccc(N2CCOCC2)nn1 +O=C(CCNC(=O)c1ccc2c(c1)OCO2)NC1CC1 +O=C(NC1CC1)c1ccc(NC(C(=O)NC2CC2)c2ccccc2)cc1 +CCCCCC(C)NC(=O)N1CCC(CC(N)=O)CC1 +CNC(=O)CCN(C)c1cc(-c2ccccc2F)nc2ccnn12 +COc1ccccc1CNC(=O)c1csc(Nc2ncccn2)n1 +COc1cc(C#N)ccc1OC(C)C(=O)c1ccc(F)cc1 +CC(Oc1cccc2ccccc12)C(=O)NCC1CCCO1 +CC(C)Nc1nc(C(=O)NCc2ccccn2)cs1 +C#CCN1CCC(C(=O)NCCN2CC(C)OC(C)C2)CC1 +Cc1ccc(OCC(=O)Nc2cccc(C(=O)NC(C)C)c2)cc1 +CC(C(=O)Nc1ccc(N2CCNC(=O)C2)nc1)c1ccsc1 +Cc1ccc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)cn1 +CN(C)c1cc(CNC(=O)C2CC=CCC2)nc(-c2ccncc2)n1 +Cc1ccc(C(=O)N2CCc3cc(N)ccc32)cn1 +COc1cc(S(=O)(=O)n2ccnc2C)c(C)cc1C +CSc1ccc(Cl)cc1NC(=O)c1cnccn1 +CC(C)NC(=O)CCNC(=O)N1CCSc2ncccc21 +Cc1noc(C)c1COC(=O)c1ccc(Cl)cc1N1CCCC1=O +COc1ccc(CCC2CCN(C(=O)c3cnn(C)c3)CC2)cc1 +Cc1ccc(C)c(S(=O)(=O)NCc2nc3cccnc3n2C)c1 +CCCC(C(=O)N1CCC(C(=O)N(C)C)CC1)c1ccccc1 +COc1ccc(C(=O)N(C(C)C)C2CCC2)c(OC)c1OC +Nc1nc2c(cc1C(=O)Nc1ccc(Cl)cc1)CCCC2 +Cc1cccc(NC(=O)c2ccc(OCC(F)F)nc2)n1 +CC(=O)Nc1ccc(OCC(=O)NCc2cccc(F)c2)nc1 +CCN(CCO)C(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C +O=C(CCc1nc(C2CC2)no1)Nc1cnn(-c2ccccc2F)c1 +CCOc1ccc(CC(C#N)c2c(C)noc2C)cc1 +CC(C)n1c(=O)oc2cc(NC(=O)NCc3cccc(F)c3)ccc21 +O=C(Nc1ccc(F)c(Cl)c1)c1ccc2c(c1)OCCO2 +O=C(c1ccco1)N1CCCC2(CN(CCO)CCO2)C1 +CC(=O)Nc1cccc(CNC2(C(=O)NCC3CC3)CCCC2)c1 +COc1cccc(OC)c1OCC(=O)c1ccc2c(c1)OCCO2 +O=C(Nc1ccccc1F)C1CSc2nccc(=O)n2C1 +O=C(NCc1cccs1)c1ccc(OC(F)F)cc1 +COCc1c(C(=O)Nc2cccc(C)c2)nnn1-c1ccc(C)cc1 +Cc1cc(NC(=O)c2nccc3c(N)ccc(F)c23)no1 +Cc1ccccc1OCC(=O)c1ccc(O)cc1O +CCc1cc(CCC(N)=O)nc(N2CCOCC2)n1 +O=C(NCCc1nnc2n1CCCCC2)N1CCOCC1C1CC1 +COc1cc(C)nc(N2CCN(C(=O)CN3CCOCC3)CC2)n1 +C=CCn1c(C2CC2)nnc1S(=O)(=O)Cc1ccccc1F +CN(CC1CCC1)C(=O)NCCCCc1cnn(C)c1 +CCCOc1nccnc1NC1CCN(S(=O)(=O)CC)CC1 +COC(=O)c1ccc(C(=O)N2CCCc3c(C)ccc(F)c32)nc1 +Cc1cc(CCn2nc(C)c(N)c2C)ccc1OC(C)C +COC(=O)CNc1ccc(C)c(Br)c1 +COCCNC(=O)CNc1ccc(F)c(Cl)c1 +COc1cccc(SCC(=O)NCc2ccco2)c1 +CC(=O)Nc1ccc(CCNC(=O)NCC(=O)NC(C)(C)C)cc1 +CCOc1ccc(C(=O)Nc2ccc(C)cc2C(=O)NC)cc1 +O=C(NC1CCN(c2ccccc2)C1=O)c1cc[nH]n1 +O=C(Cn1cncn1)N1CCC(S(=O)(=O)c2ccccc2)C1 +Cc1ccc(CNC(=O)C2(C)CCN(C(=O)C3CCC3)CC2)cc1 +CS(=O)(=O)N1CCCC12CCN(C(=O)c1ccoc1)CC2 +Cc1cc(NC(=O)CCCCCN2CCOCC2)no1 +COc1ccccc1NC(=O)CC1CCN(C(=O)OC(C)(C)C)CC1 +c1cc(-c2ncc(-c3cnccn3)c(-c3ccncc3)n2)ccn1 +COC(=O)C1CN(Cc2cccs2)CCN1C(=O)c1ccco1 +CN(C(=O)CCN1C(=O)COc2ccccc21)c1nccs1 +CCn1c(C2CCCN2C(=O)C2CC=CCC2)nc2ccccc21 +Cc1cccc(CN2CCN(C(=O)c3ccnc4ccccc34)CC2)c1 +O=C(NCCCN1CCCC1=O)c1cccnc1N1CCCCC1 +Cc1ccc(CN(C)C(=O)C2CC(=O)N(c3ccccc3Cl)C2)o1 +Cn1nccc1CNCCc1c[nH]c2ccc(F)cc12 +N#Cc1ccc(C(=O)Nc2nnc3n2CCCC3)nc1 +Cc1nccc(CNc2ccnc(C(=O)N(C)C)c2)n1 +CCN1CCN(C(=O)c2nc(C)n(-c3ccccc3Cl)n2)CC1 +C#CCNC(=O)CCc1ccc(-c2ccccc2)[nH]1 +COc1ccc(-c2ncnn2Cc2cccc(C)c2)o1 +CN(Cc1ccoc1)CC(O)c1ccc2c(c1)OCCO2 +COc1ccc(NC(=O)Nc2cnn(CC(F)F)c2)c2cccnc12 +CC(C)NC(=O)CCNC(=O)NC1CCc2cc(Cl)ccc21 +COc1cc(C(=O)N(C(C)C)C2CCC2)cc(OC)c1C +CCOc1ccc(NC(=O)C(C)Sc2nnc(C3CC3)n2C)cc1 +Cc1cc(C)cc(N(C)C(=O)c2c(C)nn(C)c2C)c1 +O=C(C1CCN(S(=O)(=O)c2ccccc2F)CC1)N1CCC1 +O=C(Cc1noc2ccccc12)NCCOc1ccccc1 +Cc1[nH]nc(-c2ccc3c(c2)N(C)C(=O)C(C)O3)c1N +CC(C)(C)OC(=O)Nc1csc(C(F)(F)F)n1 +COCc1nc(C(=O)N2CCCC(n3nc(C)nc3C)C2)cs1 +O=S(=O)(Nc1cccc(-c2cn[nH]c2)c1)c1ccc2c(c1)CCO2 +Cc1cnn(C2CCCN(C(=O)c3csc(C4CC4)n3)C2)c1 +Cc1cc(C)nc(N2CCCC(C(=O)Nc3ccc4[nH]ccc4c3)C2)n1 +CCc1ccc(C(=O)N(CC(N)=O)c2ccccc2)cc1 +COC(=O)c1cccc(NC(=O)CSc2ncn[nH]2)c1 +Nc1ccc2nc(SCc3nc4ccccc4[nH]3)sc2c1 +Nc1nc(Nc2cccc(Cl)c2)c2nc[nH]c2n1 +Cc1c(NS(=O)(=O)c2ccc(C#N)cc2)cccc1-n1cnnn1 +CN(CC(N)=O)C(=O)c1cnn(-c2ccc(Cl)cc2Cl)c1 +C=CCCCN(C)C(=O)Nc1cccc(C(=O)NC)c1C +CC1=C(C(N)=O)C(c2ccc(Cl)cc2Cl)C(C(N)=O)=C(N)O1 +CCC1c2ccsc2CCN1C(=O)c1cc(C)no1 +CC(C)C(C)(C#N)NC(=O)c1cnc(C2CCCO2)s1 +CN(C)c1nc(N)nc(Cc2nc3sc4c(c3c(=O)[nH]2)CCC4)n1 +CCCN1C(Cl)=Nc2ccccc2S1(=O)=O +CCCOc1ccc2c(c1)CCNC2c1ccncc1 +COC(=O)C1CCN(C(=O)c2cccnc2N)CC1 +Cc1nnc(CCc2ccc(Cl)c(N)c2)n1C +COC(=O)c1ccc(C(=O)N(C)C(C)c2cc(F)ccc2F)cc1 +Cc1ccc(CSc2nnc(-c3ccco3)n2N)cc1C +c1ccc(OCCN2CCN(Cc3cscn3)CC2)cc1 +Cc1ccc(C(=O)N2CCC(c3nc(C)no3)CC2)c(C)n1 +CC(=O)Nc1cccc(C(=O)NCCCC(N)=O)c1 +O=C(Nc1ccc(Br)c2cccnc12)c1ccco1 +COc1c(NC(=O)Nc2cccc(Cn3cccn3)c2)c(C)nn1C +O=C(Nc1cc(F)ccc1SCC(F)F)C1CC1 +Cc1cnc(C(=O)OCC(=O)Nc2ccc(Cl)cc2)cn1 +Cc1[nH]ncc1CCCNC(=O)c1ccc(F)cc1 +CC(C)S(=O)c1ccc(C(=O)OC2CCCC2n2cccn2)cc1 +Cc1cc(N)nc(SCC(=O)c2ccc3c(c2)OCO3)n1 +CS(=O)(=O)NC1CCCN(C(=O)c2scnc2C2CC2)C1 +Cc1cnc(C(=O)OCc2nc(-c3cccs3)no2)cn1 +O=C(CCc1nc(-c2ccsc2)no1)N1CCCC1c1ccc[nH]1 +CC(NC(=O)c1nc2cccnc2s1)c1ccccc1 +CCOC(=O)c1sc(N(C(=O)COC)c2ccccc2)nc1C +CCC(OC)C(=O)NCc1coc(-c2cccs2)n1 +O=C(CSc1nc(-c2ccccc2)cs1)NC1CC1 +COc1ccc(C(=O)Nc2ccnn2C2CCCC2)c(OC)c1 +Cc1cc(C(=O)NCC(c2ccc(C)o2)N2CCOCC2)on1 +CCOc1ccc(-c2cc(C(=O)N3CCCCC3C)n[nH]2)cc1 +CC1CN(C(=O)CCCn2cncn2)CCC1(C)O +CCOC(=O)C1=C(NC(=O)Nc2ccc(OCC)cc2)C(C)=NC1C +Cc1c(C(=O)NCCCC2CCCCC2)cnn1-c1ccncc1 +COc1ccccc1NC(=O)CNc1cccc(C)c1C(N)=O +Cc1cc(C)n2ncc(C(=O)NCc3ccccc3OC(F)F)c2n1 +C=CCCC(=O)N1CCC(Oc2cccnn2)CC1 +CC(=O)Nc1cccc(OC(=O)c2cccnc2OCC(F)F)c1 +Cc1ccc(C)c(S(=O)(=O)CC(=O)NCc2ccc(F)cc2)c1 +O=C(CCCc1nc2ccccc2[nH]1)NCc1ccccc1F +CCCCOc1ccc(-c2cc(C)nc(N)n2)cc1 +Cc1ncsc1CCOC(=O)c1cccc(S(C)(=O)=O)c1 +COc1ncccc1C(=O)Nc1nc2c(s1)COCC2 +COc1ccc(C(=O)NC2=C3N=CN=C3C=CC2)cc1 +CC(Sc1nncn1C)C(=O)N(C)CCC(F)(F)F +CCOC(=O)CSc1nnnn1-c1ccc2c(c1)OCO2 +Cc1cccc(C(C#N)CCC(=O)NC(C)(C)C)c1 +COCc1cccc(NC(=O)NCc2cccnc2)c1 +CCOC(=O)C1CCCN1C(=O)c1ccc[nH]c1=O +CC(=O)c1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +Cc1noc(C)c1COc1cccc2c1NC(=O)CO2 +Cc1csc(C(C)NCc2nc(C(C)(C)C)no2)n1 +CCn1nc(C(=O)Nc2ccc(C)cc2)c(=O)c2cc(Cl)ccc21 +Cc1ccc(NC(=O)CC2C(=O)Nc3c(-c4ccccc4)cnn32)cc1 +CC1CCN(c2cc(NC(=O)c3c[nH]c(=O)[nH]c3=O)ncn2)CC1 +CN(C)C(=O)CSc1nc2ccc(C(=O)c3ccccc3)cc2[nH]1 +CCC(C)(NC(=O)CNS(=O)(=O)CC)c1ccccc1 +CCC1CN(C(=O)c2ccnc(OC3CCC3)c2)CC(C)O1 +CCC1CN(C)c2ccccc2CN1C(=O)CNC(=O)NC1CC1 +N#Cc1cccc(C(=O)N2CCCC2c2nc(C3CC3)no2)c1 +Cc1cccc(C(=O)NCc2cccc(NC(=O)C3CC3)c2)c1C +N#Cc1cccc(OCC2COC3CN(Cc4ccc[nH]4)CC23)c1 +COC(=O)CN(c1ccc(C)c(Cl)c1)S(C)(=O)=O +O=c1nc(SCc2cccnc2)c2c([nH]1)CCCC2 +Cc1cc(NC(=O)Cc2ccccc2Cl)no1 +Cn1cccc(NC(=O)NCC(C)(O)c2ccsc2)c1=O +Cc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1C +COc1ccc(C(C)NC(=O)Nc2cn[nH]c2)cc1F +CS(=O)(=O)N1CCN(Cc2cc3cc(Cl)ccc3o2)CC1 +Cn1nnc(CO)c1-c1cccc(Br)c1 +CCOC(=O)N1CCN(C(=O)CSc2ccc(O)cc2)CC1 +Cc1nc2n(CC(=O)c3ccccc3)c3ccccc3n2n1 +Cc1cc(OCc2ccc(C(=O)NCCCO)o2)ccc1Cl +Cc1cc(CN(C)C(=O)CCc2ccncc2)no1 +Cc1ccc2nc(CN(C)C(=O)c3sccc3Cl)[nH]c2c1 +COC(=O)c1ccsc1NC(=O)C1CCCCC1 +O=C(NCc1nnc2ccccn12)c1cnc(Cc2ccccc2)s1 +Fc1ccccc1-c1n[nH]cc1CN1CCOC2(CCCC2)C1 +CCCn1c(CCNC(=O)c2ccc(C)cc2C)nc2cccnc21 +COc1ncccc1C(=O)Nc1cccc(C(=O)Nc2ccccn2)c1 +COc1ccc2oc(C(C)NC(=O)NCC3CCOC3)c(C)c2c1 +CC(C)OCCC(=O)N1CCCc2cccc(OC(F)F)c21 +CC(=O)c1ccc(NC(=O)CNC(=O)c2ccccc2)cc1C +O=C(NCc1ccco1)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CC(C)(C)OC1CCN(Cc2cnc(C(C)(C)C)s2)CC1 +CC1CC=CCC1COC(=O)CCNC(=O)C(C)(C)C +CCSc1cc(C(=O)Nc2ncccc2OC)ccn1 +Cc1csc(NC(=O)c2nn(C)c3ccc(Cl)cc3c2=O)n1 +CCC1CCC(NC(=O)C2CCCN2C(=O)C(C)C)CC1 +O=C(NCc1ccncc1)c1cccnc1OCC(F)F +O=C(NCCc1nc2ccccc2[nH]1)c1cc2c(F)cccc2[nH]1 +CC(C)Cn1ccnc(NCC(=O)NC(C)C)c1=O +O=C(Cc1ccn[nH]1)NC(CC(F)(F)F)c1ccc(F)cc1 +COc1ccc(CC(=O)Oc2ccc3cn[nH]c3c2)cc1OC +CC(=O)Nc1ccc(NC(=O)NC(C)c2ccc(F)cc2)cc1 +COC(=O)CCc1csc(COc2ccc(C)cc2)n1 +NC(=O)c1ccc(NCC(=O)Nc2ccc(F)c(Cl)c2)cc1 +Cn1ncc2c(NCc3ccccc3CO)ncnc21 +COc1ccc(Cl)c2c1N(Cc1ccncc1)C(=O)C2=O +COCCNC(=O)CN(c1c(C)cccc1C)S(C)(=O)=O +O=C(NC(C1CC1)C1CC1)N1CCCC1CN1CCOCC1 +CC(=O)Nc1ccc2c(c1)CCCN2C(=O)OC(C)(C)C +CCOCCNC(=O)N1CCC(C(=O)Nc2ccc(C)cn2)CC1 +CCCc1[nH]nc2c1C(COCc1ccccc1)CC(=O)N2 +CSc1ccc(Cl)c(C(=O)NC(C)C(=O)Nc2ccccc2)c1 +Cc1ccc(C(N)=O)cc1NC(=O)NC(C)C(C)CO +Nc1ccn(CCCn2cc(Br)ccc2=O)n1 +CC(=O)Nc1cccc(S(=O)(=O)NCC2CCCC2)c1 +O=C(CCSc1ccccc1F)OCC1CCCO1 +COc1ccc(OC)c(S(=O)(=O)NC(C)CO)c1 +O=C(NC1CCN(c2ncccn2)CC1)c1cc2c([nH]c1=O)CCC2 +Cc1ccccc1C(O)c1ccc2c(c1)C(C)C(=O)N2C +Cc1cccn2c(=O)cc(OC(=O)c3ccccc3)nc12 +COc1ccc(C2(C(=O)NCc3c(C)noc3C)CCCC2)cc1 +COC(=O)c1cccc2c1CN(CCOc1ccccc1)CC2 +CC(C)(C)c1nnc(N2CCCC3(CCOCC3)C2)o1 +O=C(Cc1csc(NC(=O)c2cnccn2)n1)NCC(F)(F)F +Cc1cc2n(n1)CCC(=O)N2CC(=O)NCc1ccccn1 +COc1cc(C(=O)NCc2nc(C)cs2)ccc1C +CC(C)CC(C)Oc1cc(CNC(=O)C2CCOC2)ccn1 +Cn1c(SCc2ncc(-c3ccc(F)cc3)o2)nnc1C1CC1 +CCOC(=O)c1c(NC(=O)Cc2ccc[nH]2)sc(C)c1CC +CC(CO)CNC(=O)NCc1ccc(NC(=O)NC(C)C)cc1 +Cc1ccc(NC(=O)N(Cc2ccncc2)C2CC2)cc1 +O=C(CCc1c[nH]c2ccccc12)Nc1cccnc1-n1cncn1 +COc1ccc(C(=O)NCc2ccccc2Cn2cccn2)c(F)c1 +O=C(c1ccnnc1)N1CCOC2C(OCc3ccncc3)CCC21 +COCC(=O)N(C)c1nnc(-c2ccc(N(C)C)cc2)s1 +COC1CC2C(=O)N3CCC(NC(=O)c4cccn4C)C3C(=O)N2C1 +CCOC(=O)CC1CCC2OCC(c3ccccc3)N12 +Cc1cccc(NC(=O)c2ccc(C(N)=O)cc2)c1 +N#Cc1cccc(NC(=O)COCC(F)(F)F)c1 +C#CCNC(=O)c1cc(-c2csc(C)n2)cn1C +CC(=O)N1CCCN(c2ccc(Br)cn2)CC1 +O=C(NCCNC(=O)N1CCOCC1)c1ccco1 +CSc1ccccc1NC(=O)CSc1nnc(N)n1C1CC1 +Cc1c(C(=O)Nc2ccc3nccn3c2)cnn1-c1ccccc1F +Cc1nc(C)c(C(=O)Nc2c(C)cccc2C(=O)N2CCCC2)s1 +Cc1ccc2nc(C)cc(C(=O)NCCOc3nonc3C)c2c1 +NC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c(F)c2)cc1 +CCOC(=O)c1csc(CNC(=O)CC2CCCC2)n1 +Cc1cc(C)c(CNC(=O)c2sc(C)nc2C)c(C)c1 +Cc1ccc(C)c(S(=O)(=O)Nc2ccc(N)cc2C)c1 +CSc1ccc(CNC(=O)c2c(C)nc(C(C)(C)C)[nH]c2=O)cc1 +CC(=O)c1c(C)nn(CC(=O)N2CCCC2c2ccccn2)c1C +CCCn1c(C)nnc1SCC(=O)NC1CCCCC1C +CCc1nc(C(=O)N(C)CCN(C)C(=O)OC(C)(C)C)c[nH]1 +O=C(Cc1cccc2ccccc12)Nc1c[nH]c(=O)[nH]c1=O +CC(=O)Nc1ccc(C(F)(F)F)cc1NC(=O)c1sccc1C +Nc1cccc(C(=O)Nc2ccccc2Br)c1 +N#Cc1cccc(C(=O)N2CCCC(c3ccn[nH]3)C2)c1 +CS(=O)(=O)NCCNC(=O)c1cnc(-c2ccccc2)s1 +O=C(Nc1nccs1)C1CCCN(C(=O)NCc2ccccn2)C1 +Nc1onc(-c2cn[nH]c2)c1-c1ccc(Cl)c(Cl)c1 +O=c1cc(CNC2=NS(=O)(=O)c3ccccc32)c2ccccc2[nH]1 +COCc1ccc(CNc2cnn(-c3ccccc3F)c2)o1 +Cc1ccccc1-n1ncc2c(N3CCCC3)ncnc21 +CCC(=O)N1CCC(Oc2nc3c(Cl)cccc3s2)CC1 +Cn1c(C(=O)NCCc2cccc(F)c2)cc2occc21 +Cc1nn(C)c(C)c1CC(C)NC(=O)c1ccnc(OC2CCC2)c1 +Cc1ccc(OCc2cc(C(=O)NC3CCOCC3)no2)cn1 +Cc1ccnn1-c1ccc(C(=O)OCC(=O)c2ccc(F)cc2)cc1 +Cc1ccccc1SCC(=O)N1CCC(C(N)=O)C1 +O=C(Cc1c[nH]c2ccccc12)NCc1ccc(-n2cccn2)cc1 +O=C(c1ccn(-c2cccc(F)c2)n1)N1CCCS1(=O)=O +CC(O)c1cccc(-c2cc(NCc3cccnc3)nc3[nH]ccc23)n1 +Cc1cc(C)n(C(=O)CCc2ccc3c(c2)OCCO3)n1 +CNc1nnc(-c2oc3ccccc3c2C2CC2)s1 +CC(C)Oc1ccccc1CSc1n[nH]c(N)n1 +Cc1c(C(N)=O)sc2ncn(C(C)C(=O)c3ccccc3)c(=O)c12 +CC(C)COCCNS(=O)(=O)c1cc(F)ccc1F +Cc1ccc(Cl)cc1Nc1ncnc(N2CCCC2)c1N +CC(C)(C)c1ccc(S(=O)(=O)Nc2cnn(C3CCOC3)c2)cc1 +O=S1(=O)CCC2=CC(C(F)(F)F)=CC(C(F)(F)F)=CN21 +COCCC(=O)Nc1cc(Cl)ccc1NC(C)=O +NCc1nc2c(c(=O)[nH]1)C1(CCCC1)Cc1ccccc1-2 +O=C(c1ccc(=O)[nH]c1)N1CCC(COc2ccccc2)CC1 +CC(C)CC(CNC(=O)c1cnn[nH]1)N1CCOCC1 +CN(C(=O)NC1CC2(CCC2)Oc2ccccc21)C1CCC1 +COc1ccccc1N1CCN(CC(=O)N2CCCC2)C1=O +O=S(=O)(c1ccc(-c2cccc(O)c2)cc1)N1CCCC1 +Cc1cc(SCc2nc3ccccc3o2)nc(C)n1 +O=C1CCc2cc(NC(=O)N(CCO)C3CC3)ccc2N1 +CCOCc1ccc(CNC(=O)c2cc(C)nn2C)cc1 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NC(C)CO)CC2)cc1 +O=C(NC(CC(F)(F)F)c1ccc(F)cc1)C1CCCOC1 +Cc1noc(CCC(=O)NCCC2CCCCC2)n1 +CC(=O)NCCNC(=O)CCc1ccc(-c2ccccc2)o1 +CC=CCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CCC +COc1cc(C(C)=O)ccc1OC(=O)CC(C)(C)C +Cc1cc(S(=O)(=O)Nc2cccc(CO)c2)c(C)s1 +CC(=O)Nc1ccc(C(=O)N2CCCCCC2)o1 +COC(=O)c1ccc(C(=O)Nc2ccnn2C2CCCC2)s1 +NC(=O)c1cnc(NC(=O)CCn2cnc3sccc3c2=O)s1 +COc1ccc(C)cc1NC(=O)COCc1cc(-c2ccco2)on1 +COc1ccnc(NC(=O)CCc2nc(-c3ccsc3)no2)c1 +Cc1cc(C(=O)N2CCC(c3nn(C)c(=O)n3C3CC3)CC2)c(C)o1 +Cc1ncc(CNC(=O)c2ccc(NC(=O)C(C)C)cc2)s1 +Cc1cccc(COc2nc(-c3cnccn3)nc(C)c2C)c1 +CC1CN(C(=O)CCCNC(=O)OC(C)(C)C)CCO1 +O=C(Nc1nc(C2CC2)cs1)c1csc(Cc2ccccc2)n1 +CC(C)(NC(=O)CCCNC(=O)c1ccccc1)c1cccc(F)c1 +CC(C)CNC(=O)CSc1ncc(-c2ccc(F)cc2)o1 +COc1cc(C)sc1C(=O)NCc1ccccc1Cn1cccn1 +CC(=O)NC1CCCN(C(=O)CC23CC4CC(CC(C4)C2)C3)C1 +CN(Cc1nc2ccccc2[nH]c1=O)CC1COc2ccccc2O1 +CCCS(=O)(=O)NCc1cccc(C(=O)NC)c1 +Nc1cccc(C(=O)NCCc2ccc(Cl)cc2)c1 +COc1ccc2nc(N3CCN(C(=O)NC(C)C)CC3)sc2c1 +CCOc1cccc2cc(C(=O)Nc3sccc3C(=O)OC)oc12 +CC(=O)NCC(=O)NCc1ccc(OCC(F)(F)F)cc1 +c1ccc(-n2nnnc2SCn2nnc3ccccc32)cc1 +O=C(NCC#CCOc1cccnc1)c1cc(-c2cccs2)n[nH]1 +NC(=O)c1cccc(OCCC(=O)NC2(c3cccc(F)c3)CC2)c1 +CN(C)C(=O)N1CCOC2(COCCN(S(C)(=O)=O)C2)C1 +CCOc1ccc2c(c1)CN(C(=O)c1sc(C)cc1OC)CC2 +Cc1ccc(CC(=O)Nc2ccnn2CC(C)C)cn1 +CC=CCn1c(N2CCN(C(C)=O)CC2)nc2c1c(=O)[nH]c(=O)n2C +Cc1cccc(NC(=O)c2cccc(S(=O)(=O)N(C)C(C)C)c2)c1 +Cc1csc(C(C)NC(=O)N(C)Cc2ccc3c(c2)OCCO3)n1 +COc1ccc(OC)c(-c2cc[nH]n2)c1OCc1ccccc1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)Nc2ccccc2C)c1C +CSc1nnc(NC(=O)CN(C)S(C)(=O)=O)s1 +CC(CNC(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1)c1ccccc1 +Cc1nc2cc(NC(=O)c3csc(C)n3)ccc2o1 +CC(=O)Nc1ccc(NC(=O)c2cn3c(n2)CCCC3)cc1 +CC(=O)N(c1nc(CN(CC(C)O)c2ccccc2)cs1)C1CC1 +Cn1nnnc1SCC1NCCc2c(O)cc(O)cc21 +Cc1ccsc1C(=O)NCCc1nnc(SCC(C)C)n1C +Nc1nc(SCC(=O)NCc2ccco2)n[nH]1 +O=C(NCCn1cnc(-c2ccccc2)cc1=O)C1CCCO1 +O=C(Cc1ccc(F)c(F)c1)N1CCOC(c2ccccc2F)C1 +Cn1nncc1CNC(CC(F)(F)F)c1ccc(Cl)cc1 +CS(=O)(=O)NCC(=O)N1CCC(Cc2ccc(CO)cc2)C1 +Cc1ccc(O)c(C(CC(=O)NCc2cccnc2)c2ccccc2)c1 +O=C1CCCN1c1ccc(Cl)c(NCc2nccn2C(F)F)c1 +O=C(Nc1ccccc1)c1cccc(OCc2ccon2)c1 +CCC(OC(=O)Cn1cnc2c(cnn2C)c1=O)c1ccc(F)cc1 +C=CCn1c(SCC#N)nc2sc(C)c(C)c2c1=O +CN(Cc1cnn(C)c1)C(=O)Nc1cccc(Cl)c1 +COc1cccc(CC(=O)NCC#CCOc2ccc(C)nc2)c1 +COC(=O)CSc1nc(-c2cccs2)n[nH]1 +CCCNC(=O)Nc1nnc(CCC(=O)OC)s1 +CCOCC1CCCN(C(=O)c2cc(Cl)ccc2Cl)C1 +Cc1ccc(C2(C(=O)N3CCC4(CCCNC4=O)C3)CC2)cc1 +Cc1ccccc1C(=O)N1CCC(c2nnc(-c3ccco3)o2)CC1 +CC(C)CC(NC(=O)c1cscn1)c1ccccc1 +CCNc1c(NS(C)(=O)=O)c(=O)oc2ccccc12 +COC(=O)c1ccc(NS(=O)(=O)c2cnc(N)nc2)cc1 +CCn1cc(CCC(=O)NCc2ccncc2)c(C)n1 +O=C(CCn1nnc2ccccc2c1=O)Nc1ccc2[nH]ccc2c1 +Cc1cc(C(C)NC(=O)c2cnn(-c3ccncc3)c2C)c(C)s1 +CC(C)c1nnnn1CC(=O)Nc1ccc(Br)cc1F +CCN(C(=O)COc1ccccn1)c1ccccc1 +CC(=O)NCc1ccc(C(=O)CSc2ccc(Cl)cc2)s1 +CC(NC(=O)c1ccc(-n2cnc3ccccc32)cc1)C1CC1 +Brc1cccnc1N1CCC(N2CCOCC2)C1 +CCOC(C)c1nccn1Cc1ccc(F)cc1F +CCCc1nc(SCC(=O)OC)c2c(=O)n(C)c(=O)n(C)c2n1 +CCn1c(SC(C)C)nc2cc(C(=O)OC)ccc2c1=O +CNc1nc(-c2csc(-c3cccc(OC)c3)n2)cs1 +CN(C(=O)CCc1ccsc1)c1ccccc1S(C)(=O)=O +COCCNC(=O)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +CCOc1cccc(CNCC(O)c2ccc(Cl)cc2)c1 +CCCN(c1nc2sccn2c1CO)C(C)C +CN(CCC(F)(F)F)C(=O)c1ccc2c(c1)CCO2 +COc1ccc(C(NCC(=O)N(C)C)C2CC2)cc1 +COc1ccccc1-c1noc(CCC(=O)Nc2cccnc2)n1 +COc1cc(N)ccc1NC(=O)c1ccc(C)cc1O +Cc1ccc(N2CCC(C(=O)Nc3nncs3)C2=O)cc1C +N#Cc1ccccc1NC(=O)Cn1cnc2cc(Cl)c(Cl)cc21 +Cc1nc(CNC(=O)CCn2c(C)c(C)sc2=O)c(C)s1 +C#CCN1CCN(Cc2csc(NC(C)=O)n2)CC1 +CNC(=O)NCC(=O)NCC1(c2cccc(Cl)c2)CC1 +O=C(Cc1ccc2c(c1)OCO2)c1c(O)cc(O)cc1O +COc1cccc(C(=O)NCc2cccc(C(N)=O)c2)c1 +COC(CNC(=O)c1cccc2ccccc12)c1ccsc1 +C#CCNC(=O)N1CCN(C(=O)c2c(Cl)cccc2Cl)CC1 +Cn1c(CNc2ccc(F)cn2)nc2ccccc21 +CC(=O)NCCCSc1nnc(-c2cccs2)n1C1CC1 +O=C(Cc1ccsc1)Nc1ccc2ccccc2n1 +Cc1c(C(=O)NCc2ccc(F)cc2F)cnn1-c1ccccc1 +COCCCn1ccc(NC(=O)NC2CCC(O)CC2)n1 +CNC(=O)COC(=O)CCc1c(C)nc2c(C#N)cnn2c1C +Cc1nn(-c2ccccc2)cc1CN1CCOC(c2cccs2)C1 +CC(C)(CNS(C)(=O)=O)c1ccc2c(c1)OCO2 +CSc1ccsc1C(=O)NCC1CCN(S(C)(=O)=O)CC1 +Cc1cc(C(=O)NCc2csc(=O)[nH]2)oc1C +CNC(=O)CCCC(=O)c1ccc(OC)c(OC)c1 +O=C(Nc1cccc2ncccc12)c1cc(F)cc(F)c1 +CCc1cc2c(=O)n(CC(=O)Nc3cc(C)ccc3C)cnc2s1 +CC1CN(C(=O)CCc2ccc(C#N)cc2)c2ccccc2S1 +Cc1nn(-c2ncc(NC(=O)Nc3ccccc3F)cn2)c(C)c1C +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1cc(F)cc(F)c1 +N#Cc1cccc(CNc2cccc(Cl)c2C#N)c1 +O=C1Nc2cccc(Br)c2C1Nc1cccnc1 +COc1ccc(NC(=O)CCc2c(C)nc(C)[nH]c2=O)cc1Cl +CCc1onc(C)c1NC(=O)c1ccc(-n2ccnc2SC)cc1 +C#CCCCCNC(=O)NCC(C)(C)c1ccncc1 +COc1cc(=O)n(-c2ccccc2)nc1C(=O)N1C(C)CCCC1C +CC1CC1CNC(=O)CNC(=O)OCc1ccccc1 +N#CCCNc1cc(-c2ccccn2)nc(-c2ccccc2)n1 +CS(=O)(=O)N1CCCC(C(=O)Nc2cccc(C(N)=O)c2)C1 +CCc1ccc(NCC(=O)N2CCC3(CC2)OCCO3)cc1F +CCC(C)(NC(=O)CNC(=O)c1cccc(Cl)c1)C(=O)OC +CCNS(=O)(=O)Cc1ccc(Br)cc1 +CCNc1nc(C(C)C)nc(OCC(C)C)c1N +CCn1cc2c(n1)-c1c(oc(C(=O)NCc3ccco3)c1C)CC2 +COC(=O)CNC(=O)c1ccc(Oc2cccc(F)c2)o1 +Cn1nc(C(=O)NCc2cc(-c3ccccc3)on2)ccc1=O +CC(C)C(NC(=O)c1ccc2[nH]ccc2n1)C(=O)Nc1ccccc1 +COc1ccccc1NC(=O)CNc1ccccc1C +Cn1c(CSc2nnnn2C2CC2)nc2cc(Cl)ccc21 +CCCCc1nc(C)c(C(=O)NC(C(N)=O)c2ccccc2)s1 +Cc1ccc2[nH]c(=O)c(CCC(=O)N3CCN(C)CC3)cc2c1 +CC(=O)NC(C)C(=O)N(C)C1CCCc2ccccc21 +COc1ccc(F)cc1NC(=O)NCCc1nc2c(s1)CCCC2 +Cc1nn(C)c(C)c1C(=O)Nc1ccc2c(c1)NC(=O)CS2 +Cn1ncc2c(NC(CO)c3ccccc3)nc(C3CCCC3)nc21 +Cc1cnc(CCNC(=O)c2sc3ccccc3c2C)s1 +CC#CC(=O)N1CCCC(Cc2cccc(OC)c2)(C(=O)OCC)C1 +O=C(NCCc1nc(-c2ccc(F)cc2)c[nH]1)c1ccccc1Cl +O=C1Nc2cc(F)ccc2C12CC(O)=Nc1c2cnn1-c1ccccc1 +CC1CN(CCNC(=O)CCn2c(=O)oc3ccccc32)CC(C)O1 +COc1ccc(C(=O)Nc2cccc(C(=O)N3CCCC3)c2)cc1 +COCCSc1nc(C(F)(F)F)nc2ccccc12 +Cc1cc(N2CCN(C(=O)c3ccc(C#N)cc3)CC2)nc2nncn12 +CS(=O)(=O)c1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1 +CC(C)COc1ccc(-c2ccc(C#N)c(=O)n2C)cc1 +CN(C(=O)Nc1nc(-c2ccccc2)cs1)C1CC1 +O=C1CCCN1c1ccc(NC2CCN(c3nccs3)CC2)cc1 +CC1CC(C)CN(c2nnnn2-c2ccccc2)C1 +COCCN(C(=O)CCc1ccc(Cl)cc1)c1ccncc1 +O=C(NCc1nncn1C1CC1)Nc1cccc(N2CCCCC2)c1 +COc1cc(Cc2nc3c([nH]2)CC(C)(C)CNC3=O)cc(OC)c1 +COc1cccc(C(=O)NCCOCC(F)(F)F)c1O +Cc1nn(-c2ccccc2)c2sc(C(=O)n3cccn3)cc12 +CCN(C(=O)Cn1ccc(=O)[nH]c1=O)C(C)c1cc2ccccc2o1 +CCOC(=O)N1CCN(C(=O)Nc2nc3ccccc3s2)CC1 +O=C(OCCCn1cccn1)c1cccc2ncccc12 +OCCc1cc2c(cc1Br)CCCC2 +CCOC(=O)C(N)Cc1nc2ccc(N)cc2s1 +CC(=O)c1cnn(-c2cc(Nc3ccc(F)c(F)c3)nc(C)n2)c1C +COc1ccccc1NC(C)C(=O)Nc1ccc(NC(C)=O)cc1 +CCC(C)C(C(=O)N(CC)CCO)c1ccccc1 +CN(Cc1cc2ccccc2[nH]c1=O)C(=O)c1cccnc1 +CN(C)C(=O)CN(C)C(=O)Cn1ccc2ccc(Cl)cc21 +CCN(CC(C)C#N)C(=O)Cn1c(C)csc1=O +Cn1ncnc1COc1ccc(S(N)(=O)=O)cc1 +O=C(CCC(=O)c1ccc(F)cc1)Nc1ccnn1C1CCCCC1 +CC(=O)Nc1cc(NCCc2ccc3c(c2)CCO3)ccc1F +O=C(NCCn1cccc1)c1cc(-c2ccccc2O)n[nH]1 +Cc1cccc(NC(=O)CC(C)c2ccccc2)n1 +Nc1ccc(Br)cc1S(=O)(=O)NCc1ccsc1 +Cc1cc(C(=O)N(C)C(C)c2ccc(S(C)(=O)=O)cc2)on1 +COC(=O)C(C)NC(=O)NCc1cccn1Cc1ccccc1C +CCCCC1C(=O)N(C)CCN1C(=O)CN(C)c1ccccc1 +COc1c(O)ccc2c1C(COc1ccc(C)cc1)NCC2 +CC(=O)Nc1ccc(S(=O)(=O)NCCC(C)C)cc1Cl +COc1ccc(OCC(=O)Nc2c(C)cc(C)cc2C)cc1 +Cc1nc2c(c(=O)n1C)CN(S(=O)(=O)NCc1ccccc1)C2 +Cc1[nH]ncc1S(=O)(=O)Nc1cccc(O)c1 +CC1(C)C(=O)C2(C(=O)NCCCN3CCOCC3)CCC1C2 +O=C(c1cc(=O)[nH]c2ccccc12)N1CCC(c2ccccc2F)C1 +CCc1cccc(OC(=O)Cc2c(C)noc2C)c1 +CCCNC(=O)c1ccc(CN2CCN(C(C)C)C(=O)C2=O)cc1 +O=C(CNC(=O)c1cccs1)Nc1nc(-c2ccccc2)cs1 +CCc1nc(CSc2ccccc2S(C)(=O)=O)n[nH]1 +O=C(CSc1nc2ccccc2[nH]1)Nc1ccnn1C1CCCC1 +COc1ccc(CNC(=O)c2cnc(C)cn2)cc1O +COCCOc1ccc(CNC(=O)NC2CC2)cn1 +COC(=O)c1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 +CCSc1nc(C)cc(C(=O)Nc2ccc(C(C)=O)cc2)n1 +CCn1c(SC(C)C(=O)N(C)C)nc2sc(C)c(C)c2c1=O +CC(C)C(=O)N1CC(c2nc(-c3cnccn3)no2)C1 +O=C(CCC(=O)c1ccc(Br)cc1)NCc1ccccn1 +CCOC(=O)CSc1nnc(-c2ccc(NC(C)=O)cc2)o1 +Cc1noc(-c2csc(S(=O)(=O)N3CCCC3)c2)c1C +COC1CCC(N(C)C(=O)c2ccn(-c3ccc(F)cc3)n2)CC1 +CC(C)(C)c1ncc(C(=O)NCc2ccncc2)c(N)n1 +CCC(CC)NC(=O)N1CCN(CC(=O)N(CC)CC)CC1 +COc1ccc(C(=O)Nc2ccc(F)cc2)c(OC)c1OC +O=C1CCc2cc(NC(=O)c3cnc(C4CCCO4)s3)ccc2N1 +Cc1ccc(C(=O)C(O)NC(=O)c2ccc(Cl)cc2)cc1 +Oc1ccc(Sc2ccc(O)cc2O)c(O)c1 +CC(Cc1c(Cl)cccc1Cl)NC(=O)CC1COC(=O)C1 +CC(=O)Nc1ccc(NC(=O)N(C)Cc2ccncc2)cc1 +CCCn1c(C)nnc1SCc1nnc(C(C)(C)C)o1 +Cc1cnc(NC(=O)c2c(C)nn(-c3ccc(F)cc3)c2C)s1 +COc1ccc(OC)c(NC(=O)c2cccc(OC(C)=O)c2)c1 +O=C(NCC(O)c1ccc(F)c(F)c1)Nc1nnc(C2CC2)s1 +C=C(C)CN(CC)C(=O)c1[nH]c(C)c(C(=O)OCC)c1C +CCCn1c(C)nnc1SCc1cn2c(C)cc(C)nc2n1 +CCN1C(=O)Cc2cc(NC(=O)COc3ccc(C)cc3)ccc21 +COC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(OC)cc1 +CCOC(=O)Nc1ccc(Br)c(C)c1 +Cc1ccc(C(=O)Nc2ccc3c(C)cc(=O)oc3c2)o1 +CC(CNCC(F)(F)F)N1CCc2ccccc21 +CC(=O)c1cc2cc(C(=O)Nc3ccc(C(N)=O)cc3)cnc2[nH]1 +CC(Cc1ccc(O)cc1)NC(=O)N1CCN(C(=O)C(C)(C)C)CC1 +COCCc1noc(C2CCCN(c3nccc(C(C)C)n3)C2)n1 +O=C(CCC1CCCO1)Nc1cccn(Cc2ccccc2)c1=O +CCC(=O)c1ccc(S(=O)(=O)C2CCCC2)cc1 +CCCCC1C(=O)N(C)CCN1C(=O)c1ccc(OC)c(F)c1 +Cc1cc(NCc2cc(-c3ccccc3)n[nH]2)n2nc(C)cc2n1 +Cc1occc1C(=O)NCC(=O)N1CCN(Cc2ccccn2)CC1 +CS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 +Cc1cc(N)n(-c2ccccc2Br)n1 +CNC(=O)C1CCN(C(=O)c2c(C)noc2C)CC1 +CN(CC(=O)NC(C)(C)C)C(=O)NCCC(=O)NC1CCCC1 +CC(C)N(CCC#N)c1cc(Br)ccc1CO +CN(Cc1cccc2ncccc12)C(=O)c1cc(-c2cnn(C)c2)[nH]n1 +Nc1nc(C2CC2)ncc1C(=O)Nc1ccncc1 +O=C(NCCCOC1CCOCC1)c1cnc(C2CCCO2)s1 +O=C(NCc1csc(N2CCCC2)n1)c1cc2c(s1)CCCC2 +Cc1ccc2[nH]c(=O)c(-c3noc(-c4ccccc4F)n3)cc2c1 +O=C(NC1CCC(O)CC1)N1CCC2(CC1)OCCO2 +CC1CC1C(=O)Nc1nnc(C(F)(F)F)s1 +CCCN(CC1CCCCC1)C(=O)Nc1cn[nH]c1 +CN(C)c1ccccc1C(=O)N1CCc2[nH]c(-c3ccccc3)nc2C1 +COc1ccc(NC(=O)CNC(=O)c2cccc(C)c2)cc1 +COc1ccccc1C(=O)N(Cc1ccccc1F)CC1CCCO1 +CC(c1ccc(F)c(F)c1)S(=O)(=O)c1nncn1C +CCS(=O)(=O)Nc1ccc(NCC(C)(C)C)cc1C +O=C(c1cnc(C2CCCO2)s1)N1CCCC2CCCC21 +COc1ccc(-c2n[nH]cc2-c2cnc(C)s2)c(O)c1 +CCCOc1ccc(C(=O)N2CCNC(=O)C2)cc1OC +Cc1ncc(C#N)c(NC(=O)CC2=CCCCC2)n1 +COCCn1cc(C(=O)NC(C)Cc2cccc(Cl)c2)ccc1=O +O=C(C1CC1)N1CCC2(COCc3cnc(N4CCOCC4)nc32)C1 +Cc1c(C(=O)N2CCN(C)CC2)sc2ccccc12 +CS(=O)(=O)c1ccc(F)c(NC(=O)c2ccnc(F)c2)c1 +Cc1cc(C)cc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)c1 +Cc1ccc(NC(=O)c2ccc3c(c2)NC(=O)C2CCCN32)cc1C +CC(C)N(C)S(=O)(=O)NC1CCN(c2c(F)cccc2F)C1 +COc1cc(OC)c(NC(=O)c2cc(C(N)=O)cs2)cc1Cl +CCN1CCN(c2ccc(NC(=O)Cc3ccccc3F)cn2)C1=O +O=C(NCc1ccccc1F)c1cc(F)ccc1Cl +CCOc1ccc(C(=O)Nc2ccc3c(c2)CC(=O)N3)cc1OCC +Cc1ccc(CCc2c(C#N)nnn2-c2nnc(C)s2)cc1 +COC(=O)CSc1nc2cc3c(cc2cc1C)OCCO3 +N#Cc1cc(Br)c(Br)cc1N +O=C(NCC1(CCO)CCOC1)c1ccc(-n2ccnn2)cc1 +CCOC(=O)c1c[nH]c2ccc(NC(=O)c3ccco3)cc2c1=O +CC(=O)N1CCc2ccccc2C1CC(=O)Nc1ccccn1 +CC(C)CC(NC(=O)c1ccn2cncc2c1)C(=O)N1CCCC1 +CCc1cccc(C)c1NC(=O)NCc1cnc(C)s1 +Cc1c(C(=O)N2CCN(C)C(=O)C2(C)C)cnn1-c1ccncc1 +COc1ccc(-c2cn(-c3ccccc3)c3ncn4ncnc4c23)cc1 +Cc1ccccc1OCC(=O)N1CCC2C(=O)NCCOC2C1 +CC1CCN(C(=O)NC(C)c2ccc(S(C)(=O)=O)cc2)C(C)C1 +CCOc1ccc(C(=O)Nc2nc(C)cs2)cc1OCC +Cn1cccc1C(=O)Nc1cc(Br)ccc1Cl +COC(=O)c1cc(=O)c2c(Cl)cc(Cl)cc2[nH]1 +Cc1nc(C)c(CCC(=O)Nc2ccccn2)c(=O)[nH]1 +COC(=O)CNC(=O)C12CC3CC(CC(C3)C1)C2 +COc1cc(C)c(C(=O)C2CCN(C(C)=O)CC2)cc1C +CCc1ccc(S(=O)(=O)N(C)CC(=O)N(C)C)cc1 +O=C(NCc1ccc(-c2nc3cnccc3o2)cc1)c1ccccc1F +CN(C)c1ncnc(N2CCN(c3ccccc3F)CC2)c1N +CCC(C)C(NC(=O)CSc1ccc(C#N)cc1)C(N)=O +c1cncc(OC2COCCN(Cc3c[nH]c4ccccc34)C2)c1 +Cc1ccc(CCNC(=O)CNC(=O)OC(C)(C)C)c(C)c1 +CCOc1ccc(NC(=O)CCCOC)c(C)c1 +O=C(Cc1cccs1)NC1Cc2ccccc2C1 +C=C(C)CN(CC)C(=O)C(C)Sc1nnc(-c2ccco2)n1N +Cc1noc(C)c1CNC(=O)N(CC1CCCCC1)C1CC1 +CCc1ncc(C(=O)NCCN2CCNC2=O)cn1 +N#CCCCn1c(Cc2ccccc2)nc2cc3c(cc21)OCO3 +CCc1nn(CC(=O)N(C)CCO)c(=O)c2ccccc12 +C=CCn1c(=O)[nH]c2sc3c(c2c1=O)CC(C)(C)OC3 +Cc1n[nH]c(C(=O)N(C2CCCCC2)C2CC2)c1Br +Cc1[nH]c2ncnc(NC(=O)c3ccc(Br)cn3)c2c1C +O=C(Cn1nnc(-c2cccs2)n1)N1CCSc2ccccc21 +Cc1occc1COC(=O)Cc1cccc2cccnc12 +Cc1cc(C(=O)NC2CCC(C(F)(F)F)CC2)c(C)o1 +Cc1ccc(C(C)Nc2cnn(C)c(=O)c2Br)s1 +COc1cnc(NCC2(Cn3cccn3)CC2)nc1-c1ccnn1C +CN(C)c1nc(Nc2ccc(F)cc2)c2cnn(C)c2n1 +CC1CN(CCCc2ccc3c(c2)NCCO3)CC(C)O1 +CCCNC(=O)CCNC(=O)NCc1cccc(Cl)c1 +CCn1nc(C)cc1C(=O)N(CC(F)(F)F)c1ccccc1OC +O=C(CC1C=CCC1)NCCCNc1ncccn1 +Cc1cc(C(=O)N2CCN(CC=Cc3ccc(F)cc3)CC2)on1 +CN(Cc1cnn(C)c1)C(=O)NCc1cccc(OCC(F)F)c1 +COc1cc(-c2noc(-c3cc4cc(F)ccc4[nH]3)n2)ccn1 +O=C(c1ccc(F)cc1Cl)N1CCc2c([nH]c3ccnn3c2=O)C1 +COCC(=O)NC(C(=O)NC(C)c1cccc2ccccc12)C(C)C +COC(=O)c1sccc1N(C(C)=O)c1ccc(OC)cc1 +COc1ccc2c(c1)NC(=O)C2OC(=O)CCc1ccc(F)cc1 +CC(=O)Nc1ccc(C(=O)NC2CCCCC2OCCC(C)C)cc1 +CC(NC(=O)CCOc1ccccc1F)c1ccc(C#N)cc1 +COc1ccccc1C(O)CCC(=O)NC(C)(C)C +CC(=O)c1cc(-c2cc(C)n(C3CC3)c2C)n(C)c1C +COC(=O)c1ccc(NC(=O)c2snnc2-c2ccccc2)cc1 +COC(=O)c1cc(CN(C)C(=O)c2cc(C3CC3)[nH]n2)oc1C +CCc1nc(COC(=O)c2ccc(S(C)(=O)=O)cc2)cs1 +O=C(CNc1ccc2c(c1)C(=O)NC2)NCC1(c2ccccc2)CC1 +CNS(=O)(=O)c1ccc(C)c(NC(=O)N2CCC(C)CC2)c1 +COc1ncccc1COc1nnc(-c2ccccc2)o1 +Cc1nc(-c2cccc(NC3CCN(C(=O)N(C)C)CC3)c2)cs1 +O=C(CNc1ccc(F)c(Cl)c1)N1CCC2(CC1)OCCO2 +COCCCC1CCCCN1C(=O)C1(c2ccccc2F)CC1 +Cc1ccc(C#N)c(=O)n1CC(=O)Nc1ccc(Cl)cc1 +COc1ccc(C(N)c2nccs2)cc1OC +CCc1nc(C2CCCN2C(=O)c2cc(C3CC3)[nH]n2)no1 +CC(C)CNC(=O)c1cnn(C(C)(C)C)c1-c1ccccc1 +Cc1ccc(NC(=O)c2n[nH]c3c2CCC3)c(OCC2CCCO2)c1 +CCC(CC)N(CCO)S(=O)(=O)c1cccc(C)c1 +CC(C)(C)c1nn(-c2ccccc2)cc1CN1CCOC(C(N)=O)C1 +FC(F)(F)c1cc(C2CCCN(c3cnccn3)C2)n2ccnc2n1 +CCSc1cc(Cl)ccc1C(=O)NCC(O)C1CC1 +O=C(NCc1cccnc1)c1c(O)cc(F)cc1F +CC1(C)Cc2cccc(OCC(=O)Nc3ccccc3C#N)c2O1 +COC(=O)NCC(=O)N1CCC(Oc2ccccc2OC)CC1 +Nc1noc2nc(C(F)(F)F)c3c(c12)CNCC3 +Cc1nnc(-c2ccccc2-c2ccc(C(=O)N(C)C)cc2)s1 +O=C(CNC(=O)c1cccc(Cl)c1)NCCCO +COc1cc(C)c(Cl)cc1-c1csc2nc(N)nn12 +CCc1ccc(NC(=O)c2cc(C(C)O)c[nH]2)cc1 +COCC(=O)NC(C(=O)NC1CCC(C)CC1)C(C)C +COc1ccccc1CNC(=O)NC1CCC(=O)NC1 +C=CCCCN(C)C(=O)Cc1c(C)nc(C)[nH]c1=O +CCCCN1C(=O)C(C)(C)N(C)c2ccc(C(C)=O)cc21 +N#Cc1ccccc1Cn1ccnc1CC(F)(F)F +Cc1noc(C(C)OC(=O)c2cccc(Cl)c2)n1 +O=C(Cn1ncc2ccccc21)NCc1cc(-c2ccccc2)on1 +COCc1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 +O=C(CCc1cccc(F)c1)Nc1ccc2c(c1)CC(=O)N2 +Cc1noc(-c2ccncc2)c1C(=O)NCc1ccccc1Cl +O=S(=O)(c1ccc(Cl)cc1)N1CCN(c2ccccn2)CC1 +COc1ccc(NCc2cc3c(C)cc(C)cc3[nH]c2=O)c(OC)n1 +O=C(CNC(=O)c1ccc(Br)cc1)OCc1ccccc1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(C)cc1C(=O)NC +Cc1nc(NC2(C(N)=O)CCCC2)c2sccc2n1 +COc1ccc(Cl)cc1C(=O)Nc1nccs1 +CS(=O)(=O)N1CCCC1C(=O)Nc1cccnc1 +CC(=O)c1ccc(NC(=O)c2cnn(Cc3ccccc3)c2C)cc1C +CN(CC(=O)Oc1ccc2cn[nH]c2c1)Cc1ccccc1 +COc1ccc(C)cc1N1CC(C(=O)N2CCCCCC2)CC1=O +Cc1cc(C(=O)Nc2ccc(C(=O)N3CCC(C)CC3)cc2)no1 +COc1ccc(OC)c(NC(=O)c2cc3c([nH]c2=O)CCCC3=O)c1 +CC(=O)c1cccc(COC(=O)c2cc(Cl)ccn2)c1 +COc1cccc(NC(=O)CC(C)n2cccn2)c1 +COC(=O)c1sc(NC(=O)CC(F)(F)F)nc1C1CC1 +COc1ccc(C(=O)CSc2nnnn2C)cc1OC +COc1cc(NCc2ccc(F)cc2)nc(C2CCCO2)n1 +CCN(Cc1cc(Br)ccc1F)C(=O)c1ccccn1 +CC(C)(C)OC(=O)N1CCc2[nH]nc(-c3cccc(N)c3)c2C1 +O=S(=O)(NCc1nnc2ccccn12)c1cc(F)ccc1F +Cc1cccc(C(=O)NCCC(=O)Nc2ccc(C(N)=O)cc2)c1 +CC(C)c1ccc(S(=O)(=O)NC(C)(C)C#N)cc1 +CNC(=O)c1ccc(OCC(=O)N(C)C2CC2)cc1 +CC1(C)CCCN1C(=O)NCc1nc(-c2ccccc2)cs1 +CC(C)(C)N1CC(C(=O)Nc2ccccc2)CC1=O +NC(=O)Cc1ccc(NC(=O)COc2ccccc2F)cc1 +CCCc1nnc(NC(=O)C2CCN(C(C)=O)CC2)s1 +O=C(NCCNC(=O)C1(c2ccc(Cl)cc2)CCCC1)C1CC1 +CN(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +CN(CCC(F)(F)F)C(=O)c1ccc(-n2ccnn2)cc1 +Cc1ccc(CN2C(=O)CCC2(C)C(=O)NC2CCCC2)cc1 +Cc1ccc(S(=O)(=O)Nc2cnn(C)c2)s1 +CCNc1nc(C)c(C(=O)NCc2cccnc2)s1 +CC(=O)Nc1cccc(C(O)CN2CCOCC2)c1 +CC(Sc1nncn1C1CC1)C(=O)N1CCCc2ccccc21 +CN(C)C(=O)Cc1ccc(NC(=O)CC2CCCO2)cc1 +Cc1ccc(CNC(=O)N2CCN(c3cnccn3)CC2)s1 +COc1ccc(-c2cc(C(=O)Nc3cc(F)ccc3OC)[nH]n2)cc1 +Cc1ccc(CNS(=O)(=O)c2ccc3c(c2)sc(=O)n3C)cc1 +CCOCc1cccc(NC(=O)NCc2nc(C)sc2C)c1 +Nc1nc(C2CCCCC2)ncc1C(=O)NC1CCCCC1 +Cc1ccc2cc(S(=O)(=O)N3CCOCC3)ccc2c1 +CCCCOC(C)c1nc(C(C)(C)NC(C)=O)no1 +CCOC(=O)CN(C(=O)CC(F)(F)F)C(C)C +Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)c(C)c1 +CCc1c(-c2ccncc2)n[nH]c1NC(=O)COCC1CC1 +CCc1cc(-c2cc[nH]n2)nc(N2CCOCC2)n1 +O=S(=O)(Nc1ccc(F)cc1F)c1ccc2c(c1)OCCCO2 +CS(=O)(=O)NCCNC(=O)NC(c1ccccc1)C1CCC1 +O=c1c2ccccc2nc2n1CCC2=Cc1ccco1 +COCC(NC(=O)NC1CC(C)N(c2ccccc2)C1)c1ccco1 +N#Cc1ccc(NC(=O)NCCc2nccn2Cc2ccccc2)cc1 +CN(C)C(=O)CCCC(=O)Nc1cc(C(C)(C)C)nn1C(C)(C)C +CCOc1cc(C#N)c(-n2cccc2)cc1OCC +O=C(CCc1nc(-c2cccnc2)no1)OCC#Cc1ccccc1 +Cc1ccc(SC(C(N)=O)c2ccccc2)cc1 +CN(c1ccc(F)c(F)c1)S(=O)(=O)c1c(F)cccc1F +Cc1nc(C(=O)N2CCC(Nc3cccnn3)CC2)cs1 +O=C(CCC1CCCC1)NCCc1ccsc1 +O=C(Nc1ccc(F)cc1)N1CCN(c2ccccc2)CC1 +CC(C)N(CC1CC1)c1ccc(S(N)(=O)=O)cc1N +CC(C)C(=O)N1CCC(C(=O)N(CCC#N)CC2CCC2)CC1 +CC(=O)Oc1c(Cl)c(=O)n(C)c2ccccc12 +CCOC(=O)C1CCCN(C(=O)CSc2cccc(C(C)=O)c2)C1 +Cc1csc(C2CCCN(C(=O)C(C)c3c(C)noc3C)C2)n1 +Cc1cccc(NC(=O)c2n[nH]nc2Nc2ccccc2)c1 +COc1ccc2nc(NC(=O)Nc3ccn(C)n3)sc2c1 +Cn1ccnc1C(=O)NCCc1csc(-c2ccccc2)n1 +COC(=O)CCC1CCN(C(=O)c2ccc(-n3ccnn3)cc2)CC1 +Cc1cc(C)c(NC(=O)COC(=O)c2ccc[nH]2)c(C)c1 +CC(C)(C)OC(=O)NCC(=O)N1CC2CC(C1)c1cccc(=O)n1C2 +CCOc1cccc(CN2CCOC(C(N)=O)C2)c1 +CN(Cc1ccccc1)c1cnn(Cc2ncccn2)c(=O)c1 +Cc1ccc(NCC(=O)Nc2ccccc2C(=O)NC(C)C)cc1F +O=C(CCC1CCCC1)Nc1ccc2nc[nH]c(=O)c2c1 +N#Cc1cccc(C(=O)Nc2ccccc2Br)c1 +O=C(CSc1nnc2sc3ccccc3n12)NC1CC1 +O=C(Cc1c(F)cccc1F)Nc1nc(C2CC2)cs1 +Cn1cc(C(=O)OCc2cncs2)ccc1=O +CCCNS(=O)(=O)c1ccc(OC)c(C(=O)NC)c1 +CCCn1cc(NC(=O)NCc2ccccc2)ccc1=O +COCc1c(C(=O)N2CC3CC4CC(C3)CC2C4)noc1C +Cc1n[nH]c(CCC(=O)N2CCOC(Cc3ccccc3)C2)c1C +O=C1COc2ccc(NS(=O)(=O)c3ccc(F)c(F)c3)cc2N1 +Cc1ccc(C(=O)NCCCNc2ccc(C(F)(F)F)cn2)cc1 +CCCc1nc(CNC2Cc3ccccc3C2)cs1 +NC(=O)c1nc(NC2CC2)sc1NC(=O)c1cccc(Cl)c1 +C=CCn1c(=O)c2ccccc2n2c(SCC(F)(F)F)nnc12 +Cc1cc2ncn(-c3ccc4nnnn4n3)c2cc1C +COc1ccc(S(=O)(=O)N2CCCC(O)C2)c(C)c1 +NC(=O)C1CCN(C(=O)NCc2cccc(Br)c2)CC1 +O=C(COc1cccc2ccc(=O)[nH]c12)NC1CCCC1 +Cc1ccccc1C(=O)NCC(=O)NC(C)C(C)C +CCCS(=O)(=O)NC1CCN(C(=O)COC)CC1 +CS(=O)(=O)NCc1nnc2n1CCN(C(=O)c1ccccn1)C2 +CCc1ccc(C(O)CNC(=O)c2ccccc2)cc1 +O=C1CC(C(=O)Nc2cccc(SC(F)F)c2)c2ccccc2N1 +Cc1ncc(N)cc1C(=O)Nc1cccc(Cl)c1Cl +O=C(Nc1nc(-c2ccc(F)cc2)cs1)C1CC1 +CCC1CCC(NC(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)CC1 +Cc1nc(NC(C)(C)CO)c2c(C)c(C)sc2n1 +CC(C)(C)Nc1nc(CCOc2ccccc2)no1 +COc1cc2oc(C(=O)c3cccc(N)c3)cc2cc1N +COc1ccc(CC(C)CNC(=O)C2CC2(C)C)cc1 +CC(=O)Nc1cc(NC(=O)C2COc3ccc(F)cc3C2)ccc1C +CC(c1ccccc1F)N(C)C(=O)c1cccs1 +CCOCCCC(=O)Nc1[nH]nc(-c2ccncc2)c1C +Cc1ccc(CNC(=O)C2CC(=O)Nc3ccccc32)cc1 +Cn1cnnc1C1CCCN(C(=O)c2cc3c(s2)CCCC3)C1 +CCCNC(=O)c1ccc(NS(=O)(=O)CC)cc1 +CNC(=O)C1CCCN1C(=O)NCCc1cc(Cl)cc(Cl)c1 +Cc1nc(CN(C)C(=O)Nc2ccc(Cn3cccn3)cc2)no1 +CCN(CC1CCOC1)C(=O)CCn1cnc2ccccc2c1=O +CS(=O)(=O)c1ccccc1NC(=O)c1cnccn1 +CC1COC2(CCN(c3ncnc4c3oc3ccccc34)CC2)O1 +Cc1cc(C)n2cc(CSc3nnc4ccccn34)nc2n1 +CCCCNC(=O)Cc1csc(NC(=O)c2cnccn2)n1 +Cc1ccc(N2C(=O)CS(=O)(=O)c3cc(F)ccc32)c(C)c1 +Cc1nn(-c2ccccc2)cc1-c1ccnc(N2CCOCC2)n1 +CCOc1cc(C(=O)Nc2cc(C)ccn2)ccc1OC +COc1ncnc2c1CCN(S(=O)(=O)c1ccc(F)cc1)CC2 +Cc1nc(-c2ccc(NC(=O)c3ccc(=O)n(C)c3)cc2Cl)n[nH]1 +COc1ccccc1CC(=O)Nc1cccn2c(C)nnc12 +Cc1cc(=O)[nH]c(SCC(=O)Nc2nc3c(C)cccc3s2)n1 +CCC(C)(C)NC(=O)Cn1nnc(-c2cccs2)n1 +O=S(=O)(c1cccc(F)c1)N(Cc1cnc2ccccn12)C1CC1 +COC(=O)C(NC(C)C)c1cc(Cl)cc(Cl)c1 +C#CCNC(=O)COC(=O)c1cccc(NC(C)=O)c1 +C#CCN(CC=C)C(=O)c1cccc(NC(=O)C2CCCC2)c1 +CN(CC1CC1)C(=O)C1CCCN1c1ncnc2sccc12 +O=C(CCCOc1ccc(Br)cc1)Nc1cccnc1 +CCCN(C)C(=O)c1ccccc1N1CCC(NC(=O)COC)CC1 +C=CCn1cnnc1Sc1cnc2ccccc2n1 +O=C(c1ccccc1-c1ncc[nH]1)N1CC(c2ccccn2)C1 +Cc1cc(C(C)NC(=O)NCc2nnc3ccccn23)c(C)s1 +CCn1cc(CN(C)C(=O)c2ccnn2C)c(C)n1 +CC1CCN(C(=O)c2nc3cccnc3n(C)c2=O)CC1 +O=S1(=O)N=C(NC(CO)Cc2ccccc2)c2ccccc21 +Nc1c(Nc2ccccn2)ncnc1Oc1cccnc1 +CCCn1nnnc1NC(=O)c1ccc(Cl)cc1Cl +CC(C)(C)OC(=O)N1CCCCC1COc1nccs1 +CCCc1noc2nc(C3CC3)cc(C(=O)NCC3CC3)c12 +Cc1nc(CC(=O)Oc2ccc(Cl)cc2C)cs1 +COC(=O)C1CN(Cc2nnc(C3CC3)n2C)c2ccccc2O1 +C=C(C)CN1C(=O)C(Cc2cccc(F)c2)Oc2cc(N)ccc21 +CCOC(=O)c1sc(N(C)C(=O)C(C)c2cccs2)nc1C +CCc1ccsc1C(=O)N1CCN(Cc2c(C)nn(C)c2C)CC1 +CC(C)n1cc(CCC(=O)Nc2cnn(C)c2)c2ccccc21 +CCC(=O)c1ccc(NC(=O)c2cccs2)cc1 +COCC(=O)NCC1Cn2nnc(-c3ccccc3)c2CO1 +O=c1ccc(-c2ccc(Oc3ccccc3)cc2)n[nH]1 +CCCOc1cc(Br)c(C(N)=O)cc1OCCC +O=C(CNC(=O)c1cccs1)c1ccc2c(c1)CCCC2 +COC(=O)C(CC(C)C)NC(=O)c1n[nH]c2ccccc12 +Cc1cc(C)cc(OCCNC(=O)N2CCOCC2)c1 +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1cn2cccnc2n1 +Nc1cc(CCc2cccc(Br)c2)no1 +COc1cc(CNCc2cn(C)nc2-c2cccnc2)ccn1 +Cc1cc2c(cc1N)CN(C)S(=O)(=O)C21CCCC1 +Cc1cccc(C)c1NC(=O)c1ccnc(-c2ccsc2)c1 +COc1ccc(Cl)c(NC(=O)CCc2c(C)nc(C)[nH]c2=O)c1 +C=CCCC1NCCc2cc(OC)c(OC)c(Cl)c21 +O=c1ccccn1CCCNS(=O)(=O)c1cc(F)c(F)cc1F +CC(C)(C)Oc1cncc(C(N)=O)c1OC1CC1 +CNC(=O)C1CCCN1S(=O)(=O)c1ccc2oc(=O)ccc2c1 +CC(Oc1ccc(C(N)=O)cc1)C(=O)c1ccc(Br)cc1 +O=C(NCCNC(=O)c1ccc(Cl)c(Cl)c1)c1ccncc1 +O=C(CNc1ccc(F)cc1)c1ccc2c(c1)OCO2 +Cc1cc(NCc2nccn2C(F)F)ccc1C(=O)NC(C)C +C=CCOC1CCN(C(=O)c2ccnnc2)C1Cc1ccccc1 +CCOc1cccc(CNC(=O)C2CCCN2S(C)(=O)=O)c1 +CCc1ccc(-c2nc(Cn3cnc(C#N)n3)cs2)cc1 +CCC1c2cccn2CCN1C(=O)CCc1c(C)nc(=O)[nH]c1C +CNC(=O)c1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)cc1 +O=C(Nc1cccnc1-n1cncn1)C1CC2CCC1O2 +CCOCCCNC(=O)N1CCN(c2ncccc2C#N)CC1 +CC(=O)c1ccc(NS(=O)(=O)N2CCCC2)cc1 +Cc1cccc(CSc2nnc(-c3ccncc3)n2N)c1 +Cn1ccc(NC(=O)C(Cc2ccccc2)NC(=O)c2cccnc2)n1 +CCc1ncc(NC(=O)c2cnn(C(C)CC)c2C2CC2)cn1 +CN(C)C(=O)CCCC(=O)Nc1ccc(Nc2ccccc2)cc1 +CC(C)C(=O)NCc1ccccc1Cn1cncn1 +O=C(NCc1ccccn1)C1CCC(=O)N1C1CCCC1 +Cc1ccnn1Cc1nnc(SCc2cc(F)ccc2F)o1 +CCOC(=O)c1cnc2c(c1)c(C#N)cn2CC(=O)NC1CC1 +COCCNC(=O)c1cc2cc(S(C)(=O)=O)ccc2n1C +CC(=O)Nc1ccc(OCc2cccc(F)c2)cc1 +CC(NCc1cc(=O)c2cc(F)ccc2[nH]1)C(N)=O +COc1ccccc1-c1noc(-c2cccc(NC(C)=O)c2)n1 +CCn1c(C)cc(C(=O)N(CCC(N)=O)Cc2ccccc2)c1C +Cc1cc(C(=O)N2CCC(O)(Cn3ccc4ccncc43)CC2)on1 +Cc1ccccc1CCc1nc2scc(N)n2n1 +CC(=O)N1CCc2[nH]nc(Nc3ccccc3)c2C1 +Cc1nc(CNC(=O)CCN(C)S(C)(=O)=O)cs1 +Cc1ccsc1C(=O)Nc1ccccc1N(C)C +Cc1oc(C)c(C(=O)N2CCN(c3ncccn3)CC2)c1C +Cc1ccc(OCCC(=O)N2CCCN(c3cccnn3)CC2)cc1 +CC(Oc1ccccc1F)C(=O)NCCOc1ccccc1 +Cc1cc(NC(=O)Cn2cnc3ncccc3c2=O)no1 +O=S(=O)(NCc1ccccc1F)c1ccccc1 +Cc1ccc(-c2cc(C)nc(N)n2)c(-n2nc(C)cc2C)c1 +CCC(C)NC(=O)NCc1ccc(Oc2ccc(F)cc2)nc1 +C=CCNC(=O)c1ccccc1NC(=O)c1cccc(OC)c1F +CN(CC1CCOC1)C(=O)NC(c1ccc(F)cc1)c1ccccn1 +CCCC(=O)N1CCCC(c2nc(CNC(=O)C(C)C)cs2)C1 +CCOc1ccc(C)cc1S(=O)(=O)NCC(O)c1ccc(C)o1 +Cc1nn(-c2cccc(Cl)c2)nc1C(=O)N1CC(C)OC(C)C1 +CN(Cc1c(-c2ccccc2)nc2ccccn12)CC1CCCO1 +CN(C)C(=O)N1CCCn2cnc(COCC3CC3)c2C1 +O=C(NCCOc1cccnc1)C1CCOc2ccccc21 +c1ccc(OC2CCC3C2OCCN3Cc2ccncc2)nc1 +C=CCNC(=O)c1ccccc1NC(=O)C(C)NC(=O)c1ccco1 +CCCc1nnc(NC(=O)C2CC3CCC2O3)s1 +Cc1cc(C)n(CC(C)CNC(=O)CSc2ccncc2)n1 +COc1ccc(-c2nc(C#N)c(N3CCOCC3)o2)cc1OC +Cc1cc(C)c(Br)c(C(=O)NCCS(N)(=O)=O)c1 +CNC(=O)c1ccc(Cl)c(NC(=O)c2cccnc2)c1 +COc1coc(C(=O)Nc2nc(-c3cccnc3)cs2)cc1=O +COc1cccc(OC)c1C(=O)Nc1ccc2[nH]c(C(F)F)nc2c1 +O=C(NCC1(c2ccc(F)cc2F)CC1)C1COc2ccccc2O1 +CCCC(=O)Nc1ccc(S(=O)(=O)Nc2nc(C)cc(C)n2)cc1 +CCn1cc2c(n1)C(COCC1CC1)CN(C(=O)c1ccco1)C2 +CCN(CC1CCOC1)S(=O)(=O)c1c(C)nn(C)c1C +CCOc1ccc(S(=O)(=O)N2CCOCC2)cc1C(C)(C)C +CC1(C)CC(NC(=O)NCc2ccccn2)C(C)(C)O1 +COc1ccc2c(ccn2CCC(=O)Nc2ccc(C(C)=O)cc2)c1 +CCC(C)NC(=O)c1ccc(NC(=O)CSc2nccn2C)cc1 +Cc1nn(C2=NC3=CC=CCC3=N2)c2c1C(=O)CC(C)(C)C2 +CC(c1ccc(S(C)=O)cc1)N(C)C(=O)Cc1ccc[nH]1 +COCC(=O)N1CCN(c2ccc(Cl)c(N)c2)CC1 +c1csc(-c2nccn2Cc2ccccc2-n2cccn2)c1 +Cc1cc(Br)cc(C)c1NC(=O)c1cccs1 +COc1ccc(F)cc1C(C#N)CC(=O)NC1CCCC1 +Cc1cccc(S(=O)(=O)N(C)C(C)c2ccncc2)c1 +Cn1c(C(=O)N2CCCC2)cc2c(Cl)cccc21 +Cc1cccc(=O)n1CCC(=O)N1CCNC(c2ccccc2)C1 +CCSc1nsc(NC(=O)c2ccccc2OC)n1 +O=C1CN(Cc2c[nH]nc2-c2ccc(F)cc2)CCN1 +COc1ccc2c(c1OC)C(=O)OC2CC(=O)c1ccc(F)cc1 +NS(=O)(=O)c1ccc(NC(=O)NCCC2=CCCCC2)cc1 +O=C(CNc1cccc(C(F)(F)F)c1)NCc1ccccc1CO +Cc1ccc(NCC(=O)N2CCC3(CC2)OCCO3)cc1Cl +Cc1n[nH]c(C2CN(Cc3nnc(Cc4ccccc4)o3)CCO2)n1 +O=C(c1noc2c1CCCC2)N1CCCC(c2ccn[nH]2)C1 +COCCN1CCN(S(=O)(=O)c2cc(C)ccc2F)CC1=O +Cc1cc(C(=O)N(C)Cc2ccn[nH]2)c(NC(=O)C(C)(C)C)s1 +CCC(=O)Nc1cc(NCC(=O)NCc2ccccc2)ccc1C +COc1cc(OC)c(C(=O)N(C)Cc2cccc(Cl)c2)cc1OC +Cc1nccc(N2CCN(C(=O)NC(C)c3cc(C)oc3C)CC2)n1 +Cc1ccc(C(C)NC(=O)Cn2c(=O)c3c(ncn3C)n(C)c2=O)o1 +CC(C)NC(=O)Nc1ccccc1NC(=O)c1cc(C2CC2)[nH]n1 +Cc1cc(-c2cc(-c3c[nH]cn3)c(C#N)c(N)n2)c(C)s1 +Cc1noc(CN2CCN(C(=O)N(C)Cc3ccccc3)CC2)n1 +Cc1nc2ccccc2n1S(=O)(=O)c1ccc(Cl)cc1 +COc1ccccc1C(C)NC(=O)CN(C)S(C)(=O)=O +CC(=O)N(C)c1cccc(NC(=O)NCCCn2cccn2)c1 +COC1CCC(CC(=O)N2c3ccccc3NC(=O)C2C)CC1 +CCCCCNC(=O)N1CCN(CC(C)(C)O)CC1 +O=C(NCc1nc(C2CC2)no1)c1cc2c(cc1O)CCCC2 +COC1CCCCC1OC(=O)c1ccc(-n2cnnn2)cc1 +Nc1cc(F)ccc1-c1nc(-c2ccsc2)n[nH]1 +O=C(CC1CCCC1)Nc1ccc(NC(=O)C2CCCO2)cc1 +O=C(CNC(=O)c1cc2ccccc2[nH]1)Nc1cccc(F)c1 +Cn1cnc2cc(-c3cn4cccc(N)c4n3)ccc21 +CC(=O)c1sc(NC(=O)CSc2ccccc2)nc1C +CC1CCCC(CNC(=O)c2cn3cccnc3n2)C1 +O=C(CSc1ccc(C(F)(F)F)cn1)Nc1ccc(F)cc1 +O=C(CO)NCCC(c1ccc(F)cc1)c1ccco1 +CCc1cnc(CN2CCN(c3ccc(C(F)(F)F)cn3)CC2)o1 +O=C(NCc1cccnc1Oc1ccccc1)C1CCC1 +CC1CN(CC(=O)N(C2CC2)C(C)C(C)C)CC(C)(C)O1 +CC(C)C(C)NC(=O)COc1ccc(C#N)cc1Cl +Cc1ccc2[nH]c3c(=O)n(Cc4cccnc4)cnc3c2c1 +COC(=O)C(C)N1CCC(Nc2ccccc2OC)CC1 +Cc1cccc(NC(=O)CSc2nc(C)c(C)[nH]2)c1 +N#CCc1nc2cccnc2n1Cc1ccc(C#N)cc1 +COc1ccc2c(c1)CCCC2CC(=O)N(C)CCO +O=C(NCc1cc[nH]n1)Nc1ccc2oc(C3CC3)nc2c1 +CCC(NC(=O)CNC(=O)c1ccccc1C)c1ccccc1 +CCc1ccc(S(=O)(=O)N2CCCC2c2cc(C)on2)cc1 +COc1cccc(CC(=O)Nc2nnc(-c3cccc(OC)c3)o2)c1 +O=C(NC1c2ccccc2CC1O)c1cccc(-c2cn[nH]c2)c1 +CC(NC(=O)N(C)C(C)C)c1nc(-c2cccc(F)c2)no1 +CC(C)n1cc2cc(C(=O)NCCCn3cccn3)sc2c1 +CN(C)S(=O)(=O)c1ccc2oc(SC3CCOC3=O)nc2c1 +O=C(CCC1CCCC1)N1CCC(Oc2cccnn2)CC1 +Cn1c(N)nc2c(c1=O)n(C)c(=O)n2C1OC(CO)C(O)C1O +COc1ccc(S(=O)(=O)N2CCC(Oc3ccccc3)CC2)cc1 +COC(=O)c1ccc(=O)n(CC(=O)NC(C)c2ccccc2)c1 +CCC(C)NC(=O)c1ccc(NC(=O)c2cccnc2N(C)C)cc1 +Cc1cc(NC(=O)CCNC(=O)c2ccc(C(C)(C)C)cc2)no1 +COC(=O)CCC(=O)Nc1ccccc1N1CCCCCC1 +Cn1cc(CNC(=O)N2CCCC2CO)c(-c2ccccc2)n1 +Cc1cc2n(n1)CCCN2CC(=O)NCc1ccc(C)o1 +CCCc1noc(COC(=O)c2c(C)nsc2NC)n1 +Cc1cccc(N2CCc3nc(N)c(C#N)c(-c4ccco4)c3C2)c1 +Cn1cc(NC(=O)c2c(O)cc(F)cc2F)cn1 +CC1CCN(C(=O)CS(=O)(=O)c2ccc3ccccc3n2)CC1 +CC(=O)c1ccc(Nc2ncnc(-n3cnc4ccccc43)c2N)cc1 +Cc1nc(-c2c[nH]c(C(=O)NCCC(C)(C)C)c2)cs1 +CCOc1ccccc1NS(=O)(=O)c1ccc(F)cc1F +COc1cc(SC)ccc1C(=O)NCc1ccncc1 +NC(=O)CSc1ccc(-c2ccc(F)cc2)nn1 +O=C(Cc1ccc(F)c(Br)c1)Nc1ccncc1 +Cc1noc(C(C)N2Cc3ccccc3CC2c2nnc(C)o2)n1 +OCCCCCc1nc2cc(Br)ccc2[nH]1 +CN(C(=O)c1c[nH]c(=O)c2ccn(C)c12)C1CCCCC1 +CCN(CC(=O)NC)C(=O)C1CC1c1cccc(Br)c1 +Cn1ncc2c(Nc3ccc(N4CCCC4=O)cc3)ncnc21 +Cc1nc2ccc(N)cn2c1C(=O)Nc1cccc(C#N)c1 +O=C(CSc1ccc(O)cc1)NCCc1ccccc1 +O=C(Nc1ccc2c(c1)COC2)N1CCN(c2cccs2)CC1 +Cn1ccc(NC(=O)CCNC(=O)Cc2ccccc2)n1 +CN(Cc1nc(-c2cnccn2)no1)Cc1[nH]nc2c1CCCCC2 +Cc1cc2cc(NC(=O)c3ccc(-n4ccnn4)cc3)ccc2[nH]1 +CCC(C)C(NC(=O)Nc1ccc2c(c1)OCO2)C(=O)OC +O=C(CCC(=O)c1ccccc1)OCc1cccc(F)c1 +O=C(CCn1ccccc1=O)Nc1ccc2oc(=O)[nH]c2c1 +CCc1onc(C)c1NC(=O)NCCCc1cccc(F)c1 +CN(CCc1ccncc1)C(=O)NC1CCCOc2c(F)cccc21 +CCCC(=O)Nc1ccc(OC(=O)c2ccsc2)c(C(C)=O)c1 +Cc1cc(C)n(C(C)CNc2nc3c(s2)c(C)nn3C)n1 +CNC(=O)Cn1c(C)c(Br)c2ccccc21 +CCCn1cc(-c2nnc3sc(-c4csnn4)nn23)c(C)n1 +COc1ccc2ccc(OC(=O)Cn3c(=O)oc4ccccc43)cc2c1 +COc1cc(C(=O)Nc2cccc3cccnc23)ccc1OC(F)F +CCOC(C)c1nc(Cn2cc(-n3cccc3)cn2)cs1 +CCn1nccc1C(=O)NCC(C)c1ccc(F)cc1 +CC(C)C(=O)NC1CCN(C(=O)Cn2cnnn2)CC1 +Cc1ccc(N2CCCC2=O)c(C(=O)NC(C)C(C)C)c1 +CC(C)(C)c1ccc(OCCCC(=O)n2ncc(C#N)c2N)cc1 +CC(=O)Oc1ccc2c(oc(=O)c3ccccc32)c1C +CSc1nc(-c2ccco2)nn1S(=O)(=O)c1ccccc1 +N#Cc1c(NC(=O)CCN2CCOCC2C2CC2)sc2c1CCC2 +N#CC1(NC(=O)Cn2cnc3sc4c(c3c2=O)CCC4)CCCC1 +Cc1ccc(OC2CCN(C(=O)Cc3ccc[nH]3)CC2)cc1C +O=C(NCCNC(=O)C1CCOCC1)c1cccnc1 +CNc1ncc(CN(C)Cc2cc(=O)c3cccc(Cl)c3[nH]2)cn1 +O=C(CCc1cccnc1)NCCc1c[nH]c2ccccc12 +Cc1ccc2c(c1F)C(c1[nH]c(=O)[nH]c(=O)c1F)NCC2 +CN(C)C(=O)c1ccc(CN2CCc3ccc(Cl)cc32)[nH]1 +COCCn1cc(NC(=O)NCC(C)(C)c2ccncc2)ccc1=O +Cc1ccc(C(=O)CNc2ccc(Cl)cc2)cc1N +O=C(OCC(=O)N1CCOCC1)c1ccc(Cl)cc1Cl +CC1CN(C(C)C(=O)N2CCC(C(N)=O)CC2)c2ccccc21 +CCCCCNC(=O)NC(C)c1ccc2c(c1)NC(=O)CO2 +O=C(Nc1ccccc1C(=O)Nc1nc2ccccc2[nH]1)c1ccco1 +COC(=O)c1cc(-c2ccc3c(c2)OCO3)nc2c(Cl)cnn12 +Cc1ccc(N2CCN(C(=O)c3scnc3C)CC2=O)cc1 +CCCn1c(=O)nc(N)c2c(-c3ccc(OC)cc3)csc21 +CC(C)c1ccc(CC(=O)N2CCN(CCO)CC2)cc1 +CCc1nc(CN(C)C(=O)C2CC(=O)N(Cc3ccncc3)C2)no1 +CCc1ccc(C2COCCN2Cc2ccn(C)c2)o1 +O=C(CCNC(=O)c1cc2ccccn2c1)Nc1ccncc1 +O=C(NCc1cn(-c2ccccc2)nn1)C1(c2ccccc2F)CC1 +CC(=O)c1cccc(NC(=O)N(C)Cc2ccccc2)c1 +CCc1cccc(NC(=O)NCCCS(=O)(=O)c2ccccc2)c1 +CC(=O)NCC1CCCN(C(=O)C(C)CC2CCCC2)C1 +Cc1cc(NC(=O)C(c2ccccc2)N(C)Cc2ccco2)no1 +COc1cccc(NC(=O)CCNS(=O)(=O)c2cccnc2)c1 +CCn1cnc2sc(C(=O)Nc3ccccc3)c(C)c2c1=O +COc1ccccc1CNC(=O)c1cc2c(cn1)OCC2 +CCc1onc(C)c1NC(=O)c1ccn(-c2ccccc2F)n1 +CCC1(CC)Nc2ccccc2C(=O)N1CCCOC +Cc1cnc2c(S(=O)(=O)N(C(C)C)C3CCC3)cccc2c1 +O=C(CCc1nc2ccccc2s1)OCC(=O)N1CCOCC1 +Cc1ccc(NC(=O)CCNS(=O)(=O)c2ccccc2)cc1 +CC(NC(=O)NCCO)c1ccc(F)cc1Cl +CCCCNC(=O)CC1CCN(C(=O)c2ccc(C)cc2)CC1 +CCn1c(=O)c(C(=O)NC(C)(C)C)nc2ccccc21 +Cc1csc(=O)n1CCC(=O)N1CC(C)Oc2cc(F)ccc21 +Cc1csc(CNS(=O)(=O)c2cc(F)cc(F)c2)n1 +Cc1onc(-c2ccncc2)c1C(=O)NCCc1ccco1 +CCCC1CN(C(=O)Nc2cccc(Cl)c2COC)CCO1 +CCCOC(=O)CC1c2ccccc2C=CN1C(C)=O +COC(=O)N1CCC(NC(=O)NCc2ccco2)CC1 +CC(C)Oc1cccc(CNc2cnn(-c3ncccn3)c2)c1 +COCC(O)CN(C)C(=O)c1n[nH]c2ccc(C)cc12 +Cc1[nH]c2cc(-c3ccc(Br)cc3)nn2c(=O)c1C +CC(=O)Nc1ccccc1OCC(=O)Nc1cc(Cl)ccc1C#N +Cc1ccccc1OCCCCC(C#N)C(=O)N1CCCC1 +Cc1cc(C)c(OCCCN2C(=O)CCS2(=O)=O)c(C)c1 +Cc1cc(C)c(OCCCn2cc(N)cn2)cc1C +CC1CCN(C(=O)c2ccc(-c3ccsc3)nc2)CC1 +Cc1ccccc1OCCCN(C)C(=O)Nc1ccncc1 +Cc1ccccc1NC(=O)C1CC2CCCC(C1)C2=O +CCCCOC(C)C(=O)Oc1ccc2c(c1)CCC(=O)N2 +CCCC(O)c1cc2c(cc1C)n(CC)c(=O)n2CC +Cc1nnc(SCC(=O)Nc2nc3c(s2)CCC3)s1 +O=C(NCc1ccco1)c1cccc(CNc2cc(F)cc(F)c2)c1 +CC(Nc1ccc2c(c1)oc(=O)n2C)C(=O)N1CCc2ccccc21 +CCOc1cc(C)c(-c2c[nH]c(N)c2C#N)cc1Cl +CNC(=O)NCC(=O)N(Cc1ccc(Cl)c(Cl)c1)C(C)C +O=C(CCn1ccc(=O)[nH]c1=O)Nc1ccc2c(c1)NC(=O)CO2 +CC(C)c1noc(CCNC(=O)c2cc(F)c(F)c(F)c2F)n1 +COc1ccc(OC)c(S(=O)(=O)NCc2ccc(F)cc2)c1 +Cc1ccnc2nc(C(=O)NCCc3cccc(F)c3)nn12 +COc1ccc2c(c1)C(c1ccc(OC)c(F)c1)NCC2 +CCC(=O)N1CCN(Cc2cn(C)nc2-c2ccncc2)CC1 +COC(=O)C(c1ccc(OC)cc1)c1ccc(OC)cc1 +COCC(C)C(=O)NC(C)C(O)c1ccc(OC)cc1 +Fc1c(Cl)ccc2c1C(C1CCOCC1)NCC2 +COc1ccc(C)cc1Nc1ncnc(N(C)C)c1N +CN(Cc1nc2ccccc2c(=O)n1C)C1(C(N)=O)CCCC1 +COC(=O)c1cc(-c2ccc(F)c(C)c2)nn1-c1ccccn1 +Cn1ncc2c(N3CCCC3Cn3cncn3)ncnc21 +COc1ccc2c(CC(=O)Nc3sccc3C(N)=O)coc2c1 +CCOC(=O)C1=C(C)NC(=O)NC1c1ccc(OC(C)=O)c(OC)c1 +CCNC(=O)c1nc(N2CCOCC2)c2c(C)scc2n1 +COCC(NC(=O)c1cc(-c2ccccc2F)on1)C(N)=O +CC(CCc1ccc(O)cc1)NC(=O)N(CCO)C1CC1 +COc1c2ccc(C(=O)Nc3ccc(SC)cc3)cc2nn1C +CC(CNS(=O)(=O)c1cncc(F)c1)Oc1ccccc1 +N#CCOc1cccc(CC(=O)N(C2CC2)C2CCc3ccccc32)c1 +OCC1c2ccccc2C(CO)c2c1ccc1ccccc21 +Cc1ccccc1NC(=O)c1ccc2nccnc2c1 +Cc1[nH]c2ccccc2c1C(=O)NCC(=O)N(C)C +Cc1cc(C)n2ncc(C(=O)N3CCc4ccccc43)c2n1 +Cc1cc(Br)c2c(c1)C(CC1CC1)NCC2 +CC1CN(c2ncc(-c3cnccn3)c(-c3ccoc3)n2)CC(C)O1 +CCc1nnc2n1CC(NC(=O)c1ccc(-n3cccn3)nc1)CC2 +Cc1cc(CN2CCN(C(=O)Nc3ccc(=O)n(C)c3)CC2)no1 +COC(=O)C(C)(C)NC(=O)c1nn(-c2ccccc2)c2c1CCC2 +CC(=O)NCC1CCN(C(=O)Cn2ccc(C(F)(F)F)n2)CC1 +NC(=O)c1cc2c([nH]c1=O)CCCC2NC(=O)C1CC=CCC1 +CC(=O)N(CC1CCCO1)c1nc2cc(C)c(C)cc2s1 +COC(=O)c1ccc2c(c1)ncn2Cc1ccc(N)nc1 +CC(C)OCCC(=O)N(C)CCc1ccncc1 +COC(=O)c1sccc1-n1cc(C#N)c(=O)[nH]c1=O +N#Cc1cccc(NCc2noc(-c3cccs3)n2)c1 +COc1ccc(CCNc2ncnc(SC)c2C#N)cc1 +CCCC(=O)Nc1cccc(CNC(=O)Nc2ccc(OC)cc2)c1 +COc1cccc(-c2noc(N3CCCCCC3)n2)c1 +Cc1cccn2c(=O)c(C(=O)NCc3ccccn3)cnc12 +COc1cc(C)ccc1OC(=O)Cc1ccc(F)c(F)c1 +Cc1cccc(NC(=O)CC(C)n2nc(C)cc2C)c1 +CS(=O)(=O)N1CCCN(C(=O)Cc2ccccc2)CC1 +O=C(NCc1ccc(F)cc1)NCC(O)c1ccc2c(c1)CCO2 +CC(=O)Nc1nc2c(s1)CN(CC=Cc1ccccc1)CC2 +O=C(COc1ccc(F)cc1Cl)NCc1cccnc1 +CCOc1ccc(-n2c(C)nc3cc(C(=O)NC4CC4)ccc32)cc1 +COc1ccc(C(=O)N2CCc3cc(F)ccc3C2)c(F)c1 +c1cc2c(cc1-c1csc(NCC3CCCO3)n1)CCC2 +O=C(NC1CC1)C1C2C=CC(C2)C1C(=O)OCC(F)(F)F +CC(Sc1nc2ccccc2[nH]1)c1nc(C2CC2)no1 +CC(C)CC(=O)NCc1n[nH]c(=O)c2ccccc12 +CS(=O)c1cccc(NCc2cnc(C(C)(C)C)s2)c1 +O=C(c1ccccc1Nc1ccncc1)N1CCCCC1 +COC(=O)C(N)C1CCN(C(=O)OC(C)(C)C)CC1 +CCOC(=O)Nc1ccc(NCC2CC2)cc1C#N +O=C(CCC1CCCCC1)N1CCC(n2cnc3cccnc32)CC1 +O=C(NC1CC1)C1CCN(C(=O)Nc2ccc3c(c2)CCO3)CC1 +O=C(Nc1ncc(Cc2cc(F)cc(F)c2)s1)c1ccncc1 +Cc1cc(S(=O)(=O)NCc2nc(-c3ccccn3)no2)ccc1F +COc1ccc(CNC(=O)c2cc(C3CC3)on2)cc1 +O=C(Cc1ccc[nH]1)NC1(c2cccc(Br)c2)CC1 +O=C(Nc1ccc(-n2cccn2)c(F)c1)c1ccc(-n2cnnc2)cc1 +N#Cc1cc2c(nc1SCC(N)=O)CCCCC2 +CN(C)c1ccc(C(=O)NCc2ccc3c(c2)OCCO3)cn1 +CN1CCOC(CNC(=O)CCc2cc(F)ccc2F)C1 +Cc1nc(CNC(=O)Nc2ccc(F)cc2OCC2CC2)c(C)s1 +CCNC(=O)c1ccc(-c2cc(CC)ccc2OC)nc1N +CC(C)CNC(=O)N1CCCC(C(=O)Nc2ccc(CC#N)cc2)C1 +Cc1nnsc1C(=O)N1CCN(Cc2ccccc2)CC1 +N#Cc1c(COC(=O)c2cncn2-c2ccccc2)cn2ccccc12 +CCN(C(=O)c1ccc(C(=O)N(C)C)cc1)c1ccc(F)cc1 +Cn1cc(CCNC(=O)NCC2(c3ccc(F)cc3F)CC2)cn1 +COc1ccc(-c2nc(C(=O)OCCN3CCCC3=O)cs2)cc1 +Cc1ccc(NC(=O)N(Cc2ccco2)Cc2ccco2)cc1 +CC(=O)NC12CC3CC(C1)CC(C(=O)Nc1nccs1)(C3)C2 +O=C(c1nc(-c2ccccc2)oc1C1CC1)N1CCN(CCO)CC1 +c1ccc(CNc2cc(-c3ccc4[nH]ncc4c3)c3cc[nH]c3n2)nc1 +Cn1ncc2c1CCCC2NC(=O)NCc1ccccc1Cl +CC(=O)NCC1CCCN(C(=O)Nc2cc(F)ccc2C)C1 +CCN(CC)C(=O)N1CCC(C(=O)N(C)Cc2ccc(O)cc2)CC1 +Cc1ccc(COc2ccc(C(=O)NC3CC3)cc2N)cc1 +COc1ccc(CNCc2ncc(-c3ccc[nH]3)s2)cc1OC +Cc1ccc2cnn(CCC(=O)Nc3cccc(F)c3)c2c1 +O=C(OCC1CN(Cc2ccccc2)CCO1)c1ccc(F)cc1F +CC(NC(=O)c1ccoc1)C(=O)Nc1n[nH]c(-c2ccccn2)n1 +Cc1ncsc1CCOC(=O)c1cccc(Oc2cnccn2)c1 +COC(=O)C1CC(Oc2ccc(F)cc2Cl)CN1 +Cn1cnc(S(=O)(=O)N(Cc2ccsc2)Cc2ccco2)c1 +CC(C)c1nc(C(F)(F)F)ncc1Br +CCc1nnc(C(C)Sc2nc(C)cc(C(F)(F)F)c2C#N)o1 +CCn1ccnc1-c1cc(F)cc(Br)c1 +Cc1nc[nH]c1C(=O)NCc1cccnc1-n1cnc2ccccc21 +CCc1cc(CNC(=O)CC2(N3CCOCC3)CCCC2)[nH]n1 +CCN(CCNC(=O)CNC(N)=O)c1cccc(C)c1 +CCN(CC)C(=O)c1ccc(CN2C(=O)COc3ccccc32)o1 +O=C1OCCN1CCSc1nc(-c2ccccc2)c[nH]1 +CCn1nnnc1SCC(=O)c1ccc(Cl)cc1 +CC(=O)NCC1CN(c2ccc(Br)cn2)CCO1 +Cc1csc(=O)n1CCC(=O)OCC(=O)NC1CCCCC1 +CC(=O)NCc1ccc(C(=O)OC2CCCCC2)cc1 +COc1ccc(Br)c(C(=O)NCC(F)(F)F)c1 +COC(=O)c1cc(-c2sc(C)nc2C)nn1Cc1ccccc1 +O=C(COc1ccccc1)NCCc1csc(-n2cccn2)n1 +CCCN(C)C(=O)C(C)NS(=O)(=O)c1ccccc1 +O=C(NCc1ccoc1)Nc1cccc2cccnc12 +N#Cc1ccc(COC(=O)CC23CC4CC(CC(O)(C4)C2)C3)c(F)c1 +COc1cccc(OC)c1OCc1cc(N)n(C)n1 +CC(C(=O)Oc1cccc(Oc2ncccn2)c1)c1cccs1 +CC(=O)N1CCCC(c2nn(C)c3ncccc23)C1 +COc1cccc(CC(C)NC(=O)NC2CCCn3nc(C)nc32)c1 +COCCNc1nnc(Sc2cccc(Cl)c2C#N)s1 +Cn1cc(CN2CCC(CN3CCOCC3)C2)c(-c2ccncc2)n1 +CCOc1ccc(C(=O)Cn2cc(Cl)cn2)cc1 +NC(=O)COc1cccc(C(=O)OCc2ccccc2Cl)c1 +COC(=O)CCn1nnc(-c2ccc(F)c(C)c2)n1 +CCOC(=O)CSc1nc2ncc3c(n2n1)CCCC3=O +O=C(c1ccc(=O)[nH]c1)N1CCN(c2ncc(Cl)cn2)CC1 +COc1ccc(N(C)C(=O)c2c(O)cc(F)cc2F)cn1 +Nc1cccc(CC(C(=O)N2CCOCC2)c2ccccc2)c1 +Cc1cc(C)cc(CC2Oc3cc(O)ccc3N(C)C2=O)c1 +Cc1c(C(=O)NC2CC2)c(=O)oc2ccc(Br)cc12 +O=C(Nc1cc(Cl)ccc1F)C1CCN(c2nccs2)CC1 +N#CCCN(Cc1cccnc1)C(=O)c1ccc(OC(F)F)cc1 +Cc1ccc(F)cc1S(=O)(=O)N1CCc2sccc2C1 +CCOc1ccc(CNc2ncccc2Cl)cc1 +CCn1ccc(C(=O)Nc2cnc3cc(OC)ccc3c2)n1 +COCc1csc(NC(=O)C(C)c2ccsc2)n1 +Cc1n[nH]cc1CNC(=O)c1sc2cccc(F)c2c1C +Cc1cnn(C(C)C(C)Nc2nc3ccccc3o2)c1 +C=CCn1c(SC(C)C(N)=O)nnc1-c1ccccc1 +Cc1cc(C(=O)Nc2cc(S(C)(=O)=O)ccc2C)c(C)s1 +Cc1ncc(CNC(=O)Nc2cccc(C#N)c2)s1 +COc1ccc(S(=O)(=O)N(C)C)cc1NCc1c(C)noc1C +CC(CC#N)N(C)C(=O)Nc1cccc(OCc2ccc(F)cc2)c1 +COc1ccc2oc(C(=O)Nc3ccccc3OC)cc(=O)c2c1 +CCN(C(=O)CN1C(=O)CSc2ccccc21)c1ccccc1 +C1=C(c2nc(-c3ccc(Cn4cnc5ccccc54)cc3)no2)CCO1 +OC(CNC1CCc2c(Br)cccc21)c1ccco1 +CCCC(=O)NCCc1nc(-c2ccccc2)n[nH]1 +CC(C)(C)OC(=O)N1CCCN(S(C)(=O)=O)CC1 +Cc1nnc2sc(-c3cc(F)c(F)c(F)c3F)nn12 +COC(=O)C(C)CN(C)Cc1cc(Br)c(OC)s1 +CC1CC(C)CN(C(=O)c2cc3ccccc3[nH]2)C1 +Cc1nc(=O)c(-c2ccccc2)c(C)n1CCc1ccc(O)cc1 +CC(=O)c1c(C)nc(C)nc1SCC(=O)N(CC(C)C)C1CC1 +CCc1nc(CC(=O)N(Cc2ccc(F)cc2)C2CC2)cs1 +COC(=O)c1c(C)cc(C)n2nc(C(C)(C)C)nc12 +Cc1cc(NC(=O)CS(=O)(=O)c2ccc3c(c2)OCCO3)no1 +O=S(=O)(Cc1ccccc1Cl)NCc1cscn1 +Cc1[nH]ncc1S(=O)(=O)N(C)CC(=O)NC(C)(C)C +CCC1CCC(CNS(=O)(=O)N(C)CCC#N)CC1 +CC(c1ccccc1F)N(C)C(=O)c1cn[nH]c1N +Cc1ccc(NC(=O)COC(=O)c2ccc[nH]2)cc1C +O=C(CNC(=O)c1ccco1)NC1CCC2CCCCC2C1 +CC1CC(C)CN(C(=O)c2cc(N)ccc2F)C1 +Cc1nccn1-c1ccc(NC(=O)c2cc(Br)c[nH]2)cn1 +NS(=O)(=O)c1ccc(CNC(=O)OCC(F)(F)F)cc1 +CCOc1cccc(CC(=O)N2CCC(O)(C(F)(F)F)CC2)c1 +CCN1C(=O)c2ccccc2NC1c1ccc(OC)c(O)c1 +Cc1ccc(Br)cc1S(=O)(=O)NCCn1ccnc1 +Cc1cn2c(CN(C)C(=O)c3scnc3C3CC3)c(C)nc2s1 +CNC(=O)c1ccc(NC(=O)c2cccc(Cl)c2)cc1 +Cc1ccccc1C(C)NC(=O)CNC(=O)OCC(F)(F)F +CC1CN(Cc2ccccc2CNC(=O)Cc2ccc[nH]2)CC(C)O1 +Cc1sc(C(=O)OCc2cnn(C)c2)cc1N +OC(COc1ccccc1F)Cn1nnc(-c2ccccc2)n1 +Cn1cnnc1SCC(=O)NCc1ccc2c(c1)OCO2 +Cc1cc(NC(=O)c2ccccc2)n(-c2nc3ccccc3n2C)n1 +CC(=O)NCC(=O)N1CC2Cc3c(n[nH]c3-c3ccncc3)C2C1 +CCN(CC(C)C#N)C(=O)Nc1ccc(F)cc1F +CCc1ccc(OC)c(S(=O)(=O)NCC(O)c2cccs2)c1 +Cc1ccc2c(CC(=O)NCC3CCCO3)coc2c1C +CC(C)COc1ccccc1-c1ccc(CO)c(=O)[nH]1 +CCc1nc(CC(=O)N2CCSc3ccccc32)cs1 +COCC(NC(=O)C1CC1c1cccc2ccccc12)C(N)=O +CCCCCc1nc2cc(OC)c(OC)cc2c(=O)o1 +CC(C)c1csc(C(C#N)C(=O)c2cc(C(N)=O)cn2C)n1 +COc1ccc(CNC(=O)c2ccccc2S(C)(=O)=O)cc1 +O=C1CC(C(=O)N2CCOCC2)c2c(F)cccc21 +O=C(NC1C2CC3CC(C2)CC1C3)C1CC(=O)N(CC(F)(F)F)C1 +O=C(NCCCn1ncc2ccccc21)c1cc(=O)[nH]c2ccccc12 +CC1CCc2noc(C3CCN(C(=O)Cc4ccsc4)CC3)c2C1 +O=C(c1ccc(-n2cnnn2)cc1)N1CCCC(c2ncc[nH]2)C1 +CCC1CCCN(C(=O)c2ccc(-n3nc(C)cc3C)nc2)C1 +CC(C)C(C#N)OC(=O)c1scnc1C1CC1 +Cc1cc(C(=O)N2CCC(C)CC2)ccc1NC(=O)NC(C)C +OCc1ccccc1N(Cc1cccs1)C1CC1 +CCN(C)c1ccccc1CNC(=O)NC1CC=CC1 +CCCCCOc1cc(C)c(C)cc1S(N)(=O)=O +O=C(c1cccc(Br)c1)N1CCN(CCO)CC1 +Fc1ccc2nc(CCCNc3nnc(C4CC4)o3)[nH]c2c1 +O=C(CN1CCN(c2ccc3c(c2)OCCO3)C1=O)NC1CCCC1 +Cn1cc(CN2CCN(CC(F)F)CC2)c(-c2cccnc2)n1 +CC1CN(CCCNC(=O)C2CCCC2)C(c2ccccc2)CO1 +Cc1ccc(NCCC(=O)c2cccc(N)c2)cc1C +Cc1ccccc1C1CC(C)N(C(=O)CCOCC(C)C)C1 +Cc1ccc(Cl)c(OC(C)C(=O)NCC2CCOC2)c1 +CCC=CCCC1CC(=O)NCc2nc3ccccn3c21 +NC(=O)c1cccc(NC(=O)CNc2cc(Cl)cc(Cl)c2)c1 +Fc1ccc(-c2nnc(COc3cccc(-n4cnnn4)c3)o2)cc1 +C=CCN(CC=C)C(=O)C(C)Sc1ccccn1 +CN(CCC(F)(F)F)C(=O)Cc1ccc(N2CCCC2=O)cc1 +CC(=O)N1CCC(NC(=O)c2ccccc2Nc2ccccc2)CC1 +c1ccc(-c2cc(CSc3nnc(Cn4cncn4)o3)no2)cc1 +CCC(C)C(C)NS(=O)(=O)c1ccc(=O)[nH]c1 +COc1ccc(N)cc1NC(=O)c1c(F)cccc1Cl +O=C(CS(=O)(=O)c1ccccn1)NC1CCCc2ccccc21 +CNC(=O)c1cc(Cl)ccc1NCC(=O)NC(C)C(C)C +CCc1cnc(CNC(=O)NC2C3CCOC3C23CCCC3)s1 +Cc1ccc(NC(=O)N2CCOC(C)(C)C2)c(Cl)c1 +CCC(NC(=O)c1ccc2c(c1)OCCO2)c1ccc(C)cc1 +O=C(c1cccc(-c2ccoc2)c1)N1CCN(c2cccs2)CC1 +CC(=O)c1cccc(NC(=O)CCn2ncc3cc(C)ccc32)c1 +Cc1ccc(C(=O)N2CCC(CN3CCOCC3)CC2)c(=O)[nH]1 +Cc1ccccc1NC(=O)Cc1cn2ccsc2n1 +O=C(COc1cc2c(cc1CO)OCO2)NC1CC1 +COc1ccccc1CCNC(=O)C12CC3CC(CC(O)(C3)C1)C2 +NC(=O)C1CCN(C(=O)NCC2(c3ccc(F)cc3F)CC2)CC1 +CCCCn1nnnc1CN1CCCC1c1noc(C2CC2)n1 +Cc1ccc(SCCC(=O)Nc2ncnc3c2CCC3)cc1 +Cn1c(N)c(-c2csc(-c3ccccc3)n2)c(=O)n(C)c1=O +CCN(Cc1nonc1C)S(=O)(=O)c1cc(C)ccc1C +COC(=O)Cn1cnc2c(oc3nc(C(C)C)c4c(c32)CCC4)c1=O +CN(C(=O)C1CCCN(C(=O)C(C)(C)C)C1)c1ccccc1 +Cc1c(CNc2ccc(C(F)(F)F)cc2)cnn1C +COC(=O)C1Cc2ncn(C(C)C)c2CN1C(=O)c1ccc(F)cc1 +COc1cccc(C(=O)NCCS(=O)(=O)N2CCCCC2)c1 +Cc1ccc(Br)c(NC(=O)NCc2ncc[nH]2)c1 +CCN(C(=O)c1ccc(Cn2cccn2)cc1)c1ccccc1 +O=C(CCn1ncc2ccccc21)Nc1ccccc1 +Cc1cccc(C)c1NC(=O)c1nnc(CN)c2ccccc12 +O=C(c1cc2ccccc2o1)N1CC(c2nc(-c3ccncc3)no2)C1 +Cc1nscc1C(=O)OCc1ccc(CC#N)cc1 +O=C(OCc1ccccc1)N1C2CCC1CC(O)C2 +CC(NC1OC(=O)c2ccccc21)c1ccccc1 +CC(Sc1ccc2c(c1)OCCCO2)C(=O)NC1CC1 +CC1CC(C)CN(C(=O)Nc2ccc(N3CCOC3=O)cc2)C1 +COc1ccc(-c2ccc(OCCNC(=O)c3ccccc3)nn2)cc1 +C#CCn1c(C2CC(=O)N(c3ccc(OC)cc3)C2)nc2ccccc21 +COc1ncc(NC(=O)Cc2ccc(F)cc2)cn1 +Cc1cc(C)n(-c2ncnc3sc4c(c23)CCCC4)n1 +CSc1nnc(-c2ccncc2)n1-c1ccc(Cl)cc1 +CCCN1C(=O)C2CCC1CN(C(=O)c1snnc1C)C2 +CCCCC(CC)c1nnc(NC(=O)c2c(C)noc2C)s1 +CC(NC(=O)c1ccccc1)C(=O)N1CCOCC1C1CC1 +O=C(Cc1c(F)cccc1Cl)NCC(=O)N1CCCC1 +CCCn1c(C)cc(C(=O)CSc2nc(=O)[nH]c(C)c2C#N)c1C +O=C1NC2(Nc3ccccc31)C(=O)Nc1cc3c(cc12)OCCO3 +O=C1CC(c2ccccc2)Cc2nc(N3CCOCC3)ncc21 +Cc1ccc(NCC(O)Cn2nnnc2-c2ccccc2)cc1Cl +Cc1csc(C2(NC(=O)c3c[nH]c(C)cc3=O)CCCCCC2)n1 +O=C(c1ccco1)N1CCN(c2ccnc(N3CCCCC3)n2)CC1 +NC(=O)c1cc2c([nH]c1=O)CCCC2NC(=O)c1ccccn1 +CC(CCc1ccc(OC(C)C)cc1)NC(=O)c1ccncc1 +Nc1cccc(SCC(=O)N2CCc3ccccc3C2)c1 +CCCC(C#N)CC(=O)N1CCc2ccccc2C1 +N#CC(C(=O)c1ccc2ccccc2n1)c1ccccn1 +CCOc1ccc(NC(=O)C(OC)c2ccccc2)cc1F +Cc1cc(C)n(CCNc2nc3c(s2)c(C)nn3C)c(=O)n1 +N#Cc1cccc(CN2CCc3[nH]nc(C(=O)N4CCCC4)c3C2)c1 +COc1ccc(S(=O)(=O)N(C(C)C)C2CCCC2)cc1 +Cn1cc(CNC(=O)N(Cc2ccco2)CC2CCCO2)cn1 +Cc1ccc(C(C)NC(=O)C(Cc2ccccc2)NC(N)=O)cc1 +COC(=O)C(NS(=O)(=O)c1ccc(F)cc1Cl)C(C)(C)C +COCCN(Cc1ccoc1)C(=O)Cc1ccc(F)cc1 +O=C(NCCNC(=O)c1ccc(Cl)c(Cl)c1)c1ccccc1 +Cc1ccc(CNC(=O)C2CC(=O)N(C)C2)c(C)c1 +Cc1ccsc1C1NC(N)=Nc2nc3ccccc3n21 +CCn1nc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)cc1C +Cc1ccc(C)c(C(=O)COC(=O)Cc2c(C)nn(C)c2C)c1 +O=C(Nc1cnn(CC(F)(F)F)c1)c1ccnc(OC2CCC2)c1 +Cc1cc(C(=O)N2CCn3c(C)nnc3C2)cc(S(N)(=O)=O)c1C +COc1ccc(F)c(NC(=O)c2ccc3c(c2)nc(C)n3C)c1 +NC(=O)C1CCN(C(=O)c2ccnc(F)c2)c2ccccc21 +CC(C)CCNC(=O)C1CCCN1S(=O)(=O)c1cccs1 +CN(C)C(=O)N1CCCC(C(=O)Nc2ccc(Cl)c(Cl)c2)C1 +Cc1cc(C)c2c(N3CCCC(C#N)C3)ncnc2n1 +Cc1ccc(-n2nnc(-c3nc(-c4ccccc4)no3)c2N)cc1 +c1ccc(-c2nc3c(c(NCc4nncn4C4CC4)n2)CCC3)nc1 +Cc1ccc(CN(C(=O)c2ccc(C)c(-n3cccc3)c2)C2CC2)o1 +CNC(=O)Cc1ccc(NC(=O)NCCCN2CCOCC2)cc1 +Cc1ccc(F)c(NC(=O)CCNC(=O)OC(C)(C)C)c1 +O=C(CSc1ccc(O)cc1)NCC1Cc2ccccc2O1 +Cn1ncc(N2CCC(CNC(=O)CCn3cnnn3)C2)cc1=O +Cc1ccc(NC(=O)CSc2ncn[nH]2)c(F)c1 +CCOC(=O)CSc1nnc(-c2cc(Cl)ccc2OC)o1 +COC(=O)CN(C)C(=O)c1cccc(OC)c1O +COC(=O)NCC1CCN(S(C)(=O)=O)CC1 +N#Cc1ccc(NC(=O)CNc2ccc(Cl)cc2)cc1 +C#CCC(C(=O)OC)c1ccc(C(=O)OC)cc1C +CCNC(=O)c1ccc(CNC(=O)c2cc(F)ccc2F)cc1 +O=C(NCCCN1CCCCCC1=O)c1ccc(F)cc1 +CC1CN(C(=O)Nc2ccccc2SC(C)CC#N)CC(C)O1 +CCCn1c(-c2ccc3c(c2)OCCO3)ccc(N)c1=O +CC(=O)Nc1cccc(NC(=O)c2cc3cccnc3n(C)c2=O)c1 +COc1cc(COC(C)=O)ccc1OCc1ccccc1 +CCOC(=O)c1cccc(Nc2c(C)nn(C)c2C)c1 +CCCCCn1nc(C(=O)Nc2nccs2)c2ccccc2c1=O +CC(C)c1nc(C2CN(C(=O)C3(C#N)CCCCC3)CCO2)no1 +O=C(NCC(O)c1cccc(OC(F)F)c1)C1CCOCC1 +Cc1cccc(-n2ccnc2SCC(=O)NC2(C#N)CCCC2)c1 +O=C(NCC(O)c1ccc(Cl)cc1)c1ccncc1 +CCC(C)(C)NC(=O)C(C)Oc1ccc2ccc(=O)oc2c1 +CCOC(=O)c1c(C)oc2ncnc(NCC(C)O)c12 +Cc1nc(N)nc(-c2ccc(OCC(C)C)cc2)c1C(N)=O +Cc1ccc(C(=O)c2c[nH]c3cc4c(cc3c2=O)OCO4)cc1C +COc1ccc(Cl)cc1-n1nc(C(C)C)nc1-c1ncn[nH]1 +CC(C)c1cc(C(=O)NCCN2CCN(c3ccccc3)CC2)n[nH]1 +COC(=O)c1c(NC(=O)CC#N)sc(C(=O)N(C)C)c1C +Cc1nnc(SCc2nc3ccccc3c(=O)[nH]2)n1C1CC1 +CC(C)(C)c1ccccc1OCC(=O)Nc1ccnc2ccnn12 +O=C(NCc1cc2ccccn2n1)c1ccc2ccccc2n1 +O=C(CCC1CCCC1)N1CCC(Cn2cccn2)CC1 +COC(=O)c1cccc(CCNC(=O)N2CCOC(C)C2C)c1 +Nc1cc(C(=O)OCC(=O)Nc2ccc3c(c2)OCO3)ccc1Cl +COC1(OC)CCN(C(=O)OC(C)(C)C)CC1=O +CC(CO)C(C)NC(=O)Nc1ccc2c(c1)CCC2 +O=C(NCCc1cnn(-c2ccccc2)c1)C1CC=CCC1 +CCC(C)NC(=O)c1cnc(-c2ccccc2)nc1N1CCOCC1 +CCCn1nc(NC(=O)COC)c2cc3cc(C)ccc3nc21 +Nc1cc(Cl)c(N)c(Br)c1N1CCCCC1 +COc1ncc(CNc2cccc(F)n2)c(OC)n1 +CC(=O)Nc1cc(NC(=O)C(C)Oc2ccccc2)ccc1C +Cc1cc(C)cc(NC(=O)COc2nc(C)nc3ccccc23)c1 +CCC(C)n1nccc1NC(=O)c1scnc1C1CC1 +CCCCNc1ncnc(N2CCN(CCO)CC2)c1N +CCOc1ccc(CNC(=O)CCn2ncc3ccc(C)cc32)cc1 +Cc1cc(OCc2ccon2)c(C(C)C)cc1-n1cnnn1 +CC(C)Cc1nc(C(=O)NC2CCCCC2C)cs1 +CC1CCCC(N(C)C(=O)CCCNC(=O)c2ccccc2)C1 +CCOC(=O)c1cccc(OC(=O)Cn2c(C)c(C)sc2=O)c1 +CCS(=O)(=O)NCCNC(=O)NC(C)(C)c1nc(C)c(C)s1 +CCN(CC)C(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 +O=C(C1COCCO1)N(Cc1cccs1)C1CC1 +O=C(NCCOc1cccnc1)c1ccc2c(c1)C(=O)c1ccccc1-2 +Cc1ccccc1S(=O)(=O)N(C)C(C#N)C(C)C +O=C(CNc1ccc(-n2nccn2)cc1)NCc1ccco1 +CC(=O)Nc1ccc(NC(C)C(=O)N2CCC(C)CC2)cc1Cl +Cc1nc(CCOc2ccccc2)[nH]c(=O)c1CCO +COc1cc2ncn(CCC(=O)NC(C)C)c(=O)c2cc1OC +N#Cc1ccc(CN2CCN(C(=O)c3ccc(F)cc3)CC2)cc1 +CC(C)CCn1c(SCC(C)O)nc2c1c(=O)[nH]c(=O)n2C +Cc1nc(C)c(CCC(=O)Nc2ccc(-n3ccnc3)nc2)c(=O)[nH]1 +CCOc1ncccc1CNC(=O)Nc1cccc(NC(C)=O)c1C +CSc1ccc(CNC(=O)N2CCCC(CO)C2)cc1 +Cc1nc(CCOc2ccccc2F)sc1C(C)(C)O +CC(C)C(=O)Nc1ccc(NC(=O)c2ccccc2)nc1 +COc1cccc(CNC(=O)Cn2cnc3sccc3c2=O)c1 +Cn1cnnc1C1CCCCN1C(=O)Cc1ccsc1 +C=CCNC(=O)Nc1cccc(-n2nnnc2SC)c1 +Cc1cc(SCCN2CCOCC2)nc2ccccc12 +Cc1cc(C(=O)Nc2ccnc3c(F)cc(F)cc23)c2ccccc2n1 +O=C(Cc1ccc2c(c1)OCO2)N1CCOCC1C1CC1 +COc1ccc(CN(C)C(=O)NCC2(C)CCCC2)cc1O +CC(c1ccccn1)N(C)C(=O)C1CCN(C(=O)OC(C)(C)C)C1 +CCn1ncc(NC(=O)c2cc(OC)cc(OC)c2)c1C(N)=O +C=CCOC1C2CCC1N(Cc1cnn(C)c1)CCO2 +Cc1ncsc1C(=O)OCCOc1ccccc1 +O=C(COC(=O)c1ccsc1)NCc1cccs1 +Cc1csc(CNC(=O)c2ccc(Cn3nc(C)cc3C)cc2)n1 +Cc1ccsc1CNS(=O)(=O)c1ccc2c(c1)C(=O)NCC2 +CC(CC#N)N(C)C(=O)Nc1cc(F)ccc1Cl +Cc1cccc(C)c1NC(=O)NCc1ccnc(OC2CCC2)c1 +CCc1noc(COc2cc(OC)ccc2C(C)=O)n1 +CC1COCCN1C(=O)CCC(=O)c1ccc2ccccc2c1 +O=C(CN(Cc1ccco1)C(=O)C1COCCO1)Nc1ccccc1 +CCCn1nc(C)c(CN2CCOC(c3ccc(F)c(F)c3)C2)c1C +CC(=O)NC(C)C(=O)NCC1(c2ccccc2C)CCOCC1 +Cn1cnc2cc(-c3nc4ccc(Cl)cn4c3N)ccc21 +O=C(CC1CCC1)NC1CCCN(c2cccnc2)C1=O +CCOC(=O)c1c(C)[nH]c(C)c1S(=O)(=O)Nc1ccc(F)cc1 +Cc1noc2nc(C3CC3)cc(C(=O)N(CC3CCOC3)C3CC3)c12 +CCc1cc(=O)[nH]c2cc(NC(=O)c3ccc(=O)oc3)ccc12 +COc1ccccc1SCC(=O)N1CCN(C(C)=O)CC1 +Cc1ccc(C(=O)NCc2cn(-c3ccccc3)nn2)c(O)c1C +Cc1noc(C)c1S(=O)(=O)N1CCCC1c1ccc(Cl)cc1 +c1cnc(N2CCCC(Cc3ccc(N4CCCC4)nn3)C2)nc1 +O=C(Nc1ccc2c(c1)CCC2)Nc1ccccn1 +Cc1csc(CNc2ccc3ccccc3c2)n1 +CCOc1ccc(CC2CNc3cc(O)ccc3O2)cc1 +CC(OCC1CC1)C(=O)Nc1ccccc1Sc1nccn1C +Cc1csc(N2CCN(Cc3ccc(C(N)=O)cc3)CC2C)n1 +NC(=O)C1(CNC(=O)c2ccc(C3CCCCC3)cc2)CCOCC1 +Cn1c(NS(=O)(=O)c2cncc(Cl)c2)nc2cc(F)ccc21 +CC(C)(CNC(=O)Cc1coc(-c2ccccc2)n1)c1ccncc1 +COC(=O)c1cc(S(=O)(=O)NC2CCCC2)cn1C +CCN(Cc1ccoc1)C(=O)NCC(C)(C)NS(C)(=O)=O +O=c1c2ccccc2ncn1CCc1ccncc1 +O=C(CSc1ncc2ccccn12)NCCc1ccc(F)cc1 +CC(C)C(=O)NCCNC(=O)NC1(C)Cc2ccccc2C1 +Cc1ccc(S(=O)(=O)Nc2cccc(C(N)=O)c2)s1 +O=C(c1cccn1Cc1cccs1)N1CCCC(n2cccn2)C1 +Cc1nnc2c(NCc3ccccc3COC(C)C)nccn12 +CC(C)CC=C(c1ccccc1)C(n1cncn1)n1cncn1 +Nc1nc2c(cc1C(=O)Nc1ncccn1)CCC2 +CCCNc1nnc(-c2sc(COC)nc2CC)s1 +Cc1ccccc1C=c1sc2nc(-c3ccncc3)nn2c1=O +O=C(NCCNc1ccc2ccccc2n1)NC1CCC(O)CC1 +Cc1cc(=O)c(O)c(CN(C)CCO)n1Cc1ccccc1 +Cc1cc(OCC(=O)NCC(C)O)ccc1Cl +Cn1cnc(CNC(=O)N(Cc2ccoc2)C2CCCCC2)n1 +CC(=O)Nc1cccc(NC(=O)Cc2ccc[nH]2)c1 +O=C(c1cc2c([nH]1)CCCC2)N1CCC(CCN2CCOCC2)CC1 +C#Cc1cccc(NC(=O)Nc2cccc(F)c2)c1 +CCc1ccc(S(=O)(=O)Nc2cccc(NC)c2)cc1 +O=C(Oc1ccccc1Br)C1CCCO1 +Cc1nc(-n2nc(C)c(C)c2O)sc1C(=O)Nc1ccccc1 +C=CCNC1=NS(=O)(=O)c2cc(N3CCCCC3)ccc2N1 +Cc1nc(CCNC(=O)Nc2ccc3ccccc3c2)cs1 +Cc1ccccc1CN(C)c1ccc(C(=O)Nc2nncs2)cn1 +Nc1nncc(-c2ccc(F)c(F)c2)c1C(=O)N1CCCC1 +CC(CNC(=O)Nc1cccc(F)c1F)Cn1cccn1 +CCN(CC1CCCO1)C(=O)NCc1ccccc1OC(F)F +N#Cc1nnn(-c2cc(Cl)cc(Cl)c2)c1-c1cccnc1 +O=C(CC1C=CCC1)N1CCC(n2cnc3ccccc32)CC1 +CN(c1ccc(OC(=O)C2CC2)cc1)S(=O)(=O)c1ccccc1F +CC(O)(C(=O)NCCc1nc(-c2ccncc2)n[nH]1)c1ccccc1 +Cc1nc(-c2ccc(CNC(=O)C3COc4ccccc4C3)cc2)no1 +CCC1Oc2ccc(C)cc2N(CC(=O)NCCOC)C1=O +Cc1csc(NC(=O)c2csc(-c3cccs3)n2)n1 +Cc1ccc(C(=O)CCC(=O)Nc2ccnn2C(C)C)cc1 +Cn1cccc1CN(C(=O)C1CC=CCC1)C1CC1 +Cc1nn(C)c2nc(Nc3c(N4CCCC4)nn(C)c3C)sc12 +O=C(COc1cccc2cccnc12)NCc1ccccc1F +Cc1nc(Cc2nc(-c3cc(F)ccc3F)cs2)cs1 +Cn1c(CNc2nnc(C3CC3)o2)nc2ccccc21 +COCC(C)NC(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1 +CNC(=O)c1ccc(CN(C)C(CCO)c2ccccc2)cc1 +O=C(COC(=O)c1ccc2c(c1)OCCO2)Nc1cccc(F)c1 +O=C(NCCN1CCOCC1)c1n[nH]c2cc(Cl)ccc12 +Cc1csc(-c2ccc(OCCCC(N)=O)c(N)c2)n1 +CNC(=O)c1nn(C)cc1NC(=O)c1cc(C)cc(C)c1 +CCCCCC(=O)N1CCC(Oc2ccccc2)CC1 +Cn1c(COC(=O)c2cccnc2)nnc1C1CC1 +CCC(C)NC(=O)c1cccc(CNC(=O)c2ccccn2)c1 +COC(=O)c1cc(NCC(=O)NC2(C#N)CCCC2)c(F)cc1F +Cc1cccc(C(=O)Nc2c(C)cc(O)cc2C)c1 +CC(C)COc1ccc(CNC(=O)Nc2cnn(C)c2)cc1 +CC(C)Oc1ccc(C(=O)Oc2cccc(N3CCCC3=O)c2)cn1 +CC(c1nc(N)nc(Nc2ccccc2)n1)N1CCC(C(N)=O)CC1 +COc1csc(C(=O)OCc2ncn(-c3ccccc3)n2)c1 +Cc1ccc(N2CCOC3CC(COCc4ccccn4)CC32)nn1 +Cc1cc(C(=O)NCCc2cccc(Cl)c2)on1 +Cc1n[nH]c(C)c1NC(=O)c1cn(Cc2ccccc2)c2ccccc12 +COc1ccc(NC(=O)c2ccncc2Cl)c(NC(=O)C(C)C)c1 +COc1cc(C(=O)Nc2nc(C(C)=O)cs2)cc(OC)c1C +CCCC1CCC(c2cc(OC)c(OC)c(OC)c2)O1 +CCc1cc(C(=O)N2CCCC(c3cc4cccnc4[nH]3)C2)on1 +CC1CCCC(NS(=O)(=O)c2ccc(C(N)=O)cc2)C1 +CCOC(=O)c1c(C)nc(N)nc1-c1ccccc1Cl +Cc1cc(C(=O)c2cc(S(C)(=O)=O)co2)n[nH]1 +C(=Cc1nn2c(-c3cnccn3)nnc2s1)c1cccnc1 +CCN(c1ccccc1)S(=O)(=O)c1ccc2c(c1)CC(=O)N2C +Cc1cccc(C)c1OCCN(C)S(=O)(=O)c1c(C)noc1C +CC(C)CC(C(=O)Nc1cc(F)ccc1O)N1CCCCC1=O +COc1ccc(OC)c(-n2nc(CC#N)c(=O)cc2C)c1 +Cc1ccc(C)c(OCC(=O)Nc2ccc(CNC(N)=O)cc2)c1 +CN(Cc1cnn(C)c1)C(=O)NCCOCC(F)(F)F +CCOC(=O)c1c(NC(=O)Cn2ccccc2=O)sc(C)c1CC +Cc1ccc(CNCCc2nnc3ccccn23)cc1 +CCC(C)NC(=O)Nc1ccc(S(=O)(=O)CC2CCOC2)cc1 +COc1ccc(CCNC(=O)CN(C)S(C)(=O)=O)cc1 +CCOC(=O)c1cc2c(=O)[nH]c3ccccc3c2s1 +Nc1cc(F)ccc1S(=O)(=O)Nc1c(F)cccc1F +CC1(C)C(NC(=O)c2sccc2SC(F)F)C2CCOC21 +COC(=O)C1CCCN1C(=O)C(C)n1cncn1 +NC(=O)C1CC(=O)N(c2ccc(CN3CCOCC3)cc2)C1 +OC1=Nc2c(ncn2-c2cc(F)ccc2F)C(c2ccccc2)C1 +CC(C)(C)OC(=O)N1CC(CNc2ccc(F)cc2)C1 +Cc1ccc(S(=O)C(C)C(=O)NCC(F)(F)F)nc1 +O=C(C1CCCC1)N1CCC2(CC1)OCCCO2 +COC(=O)c1cnc(C(C#N)c2cccn2C)c2ccccc12 +Cc1cc(C)n(-c2ccc(Cn3cnc4ccccc4c3=O)cc2)n1 +C=CCNC(=O)c1ccc(C)c(NS(C)(=O)=O)c1 +Cc1ccc(C(=O)NCC2(C(N)=O)CCCC2)c(C)c1 +O=C(NCc1nc2ccccc2[nH]1)c1ccccn1 +Cc1cccc2[nH]c(C3CCN(C(=O)C4CN(C)C(=O)N4)CC3)nc12 +CCn1cnc2cc(NS(=O)(=O)c3ccc(SC)cc3)ccc21 +COC(=O)CC1CCCCN1C(=O)c1ccc(F)cc1Cl +COC(=O)c1ccc(Cl)c(NC(=O)COc2ccccc2C#N)c1 +CCN(CCCNC(=O)c1cnc2ccc(C)cn12)S(C)(=O)=O +CC(C)c1ncc(C(=O)NC2(c3cc(F)ccc3F)CC2)cn1 +CCC(NC(=O)N(C)Cc1ccncc1)c1ccc2c(c1)OCCO2 +Cc1ccc(C(C)NC(=O)c2c(-c3ccccc3Cl)noc2C)o1 +COc1ccc(CNC(=O)Nc2ccncc2)cc1 +COc1cc(N2CCc3onc(-c4cccc(F)c4)c3C2)ncn1 +CC(Oc1cccc(C#N)c1)C(=O)Nc1ccccc1OC(F)F +O=S1(=O)N=C(NCCCO)Nc2ccccc21 +O=C(Nc1nnc(Cc2ccc(F)cc2)o1)c1c[nH]c2ccccc12 +CCCC(=O)N1CCCC(C(=O)NC2CCCC(C(F)(F)F)C2)C1 +Cc1nc(CC(=O)N2CC3CC(C2)c2cccc(=O)n2C3)cs1 +CC(C)(C)n1nc(C2CC2)cc1C(=O)OCC(N)=O +COCc1ccc(C(=O)N(C)Cc2ccccc2Cl)cc1 +C=CCn1c(SCC(N)=O)nnc1C(C)(C)C +COc1ccc(N2CCCS2(=O)=O)cc1NC(=O)C1CCCC1 +CCCOc1ccccc1C=c1sc2ncnn2c1=O +CCCc1nnsc1C(=O)Nc1cnn(CC(=O)N(C)C)c1 +N#Cc1noc(C(=O)NCCN2CCOCC2)c1N +Cc1ccc(C(=O)OCC#N)cc1NC(=O)c1ccco1 +CCOCc1ccccc1NC(=O)Cc1ccc(F)cc1F +O=C(Nc1ccc(F)cc1)C1CC=CCC1C(=O)N1CCCCC1 +Cc1sc(=O)n(CC(=O)NCCc2ccccn2)c1C +CCOc1ccc(C(=O)N2CCC(C(N)=O)CC2)cc1OC +CC(C)N(Cc1cccc(Cl)c1)C(=O)C1CCC1 +Cc1ccc(-c2nnc(SCC(=O)Nc3ccncc3)n2C)cc1 +COc1cc(NC(=O)c2ccc3c(c2)OCO3)c(OC)cc1Cl +COc1cccc(C(=O)NC(C(N)=O)C(C)C)c1F +O=C(c1cnc2ccccn2c1=O)N1CCN(Cc2ccccc2)CC1 +Cc1ccc(C)c(OCCC(=O)Nc2c(C)n[nH]c2C)c1 +CC1(C)C(=O)C2(C(=O)Nc3ccc(C(F)(F)F)cc3)CCC1C2 +O=C(Cc1ccc[nH]1)NCC(=O)Nc1ccc(F)cc1 +O=C(Nc1cnc(C2CC2)nc1)c1cc(C2CC2)[nH]n1 +O=c1[nH]c(CO)nc2scc(-c3ccccc3Cl)c12 +CC(Nc1ccc(C#N)cc1)c1ccc2c(c1)OCCCO2 +Cc1noc(C)c1COC(=O)c1ccc2c(c1)OCCO2 +Cc1nccc(C(=O)N(CC(=O)OC(C)(C)C)c2ccccc2)n1 +CCCCn1c(N)c(N(C)C(=O)C2CC2C)c(=O)[nH]c1=O +NC(=O)c1ncc(Br)c2ccccc12 +Cc1ccc(F)cc1NC(=O)CCNC(=O)C(C)(C)C +CCC(C)C(=O)Nc1nc(C)c(-c2nccn2C)s1 +CNC(=O)c1cccc(NC(=O)N2CC(C)CCC2C)c1C +O=C(NCC(F)(F)F)c1ccc(COc2ccc(F)cc2)o1 +CCNC(=O)c1csc(COc2ccc(F)cc2F)n1 +Cc1ccccc1CCc1nnc2ccc(N)cn12 +CN1CCOc2ccc(NC(=O)Nc3cccc(Cl)c3)cc2C1=O +Cc1ccccc1-c1cccc(CN(C)Cc2nnc(C)n2C)c1 +CCc1c(C)sc2ncn(C3CCCCNC3=O)c(=O)c12 +O=C(Nc1ccc2nc[nH]c2c1)c1ccccc1Cl +COCc1nn2c(C#N)c(-c3cccs3)nc2s1 +Cc1nn(C)c(N)c1S(=O)(=O)NC1CCCCC1C +CCn1nc(C(=O)Nc2cc(Cl)cc(Cl)c2)ccc1=O +Cc1ccncc1NC(=O)NCc1ccc(-n2ccnc2)cc1 +Cc1ccc(CNC(=O)c2nnc(CN3CCOC(C)C3)s2)cc1 +O=C(Nc1ccc(O)c(Cl)c1)C1CCc2cn[nH]c2C1 +CCc1onc(C)c1NC(=O)c1cc2ccc(C)cc2[nH]1 +CC(=O)NCCCNC(=O)c1cncn1-c1ccc(F)cc1 +COc1ccc2c(CSc3nccn3C)cc(=O)oc2c1 +CC(C)C(Sc1nnc(C2CC2)n1C)C(=O)NC1CCCC1 +CN(C)C(=O)COc1cccc(NC(=O)c2ccc3ccccc3n2)c1 +Cc1onc(-c2ccncn2)c1C(=O)NCCc1ccncc1 +COc1ccc(C(N)=O)cc1NC(=O)NC(C)c1cn(C)nc1C +CNS(=O)(=O)c1ccc2c(c1)NCC(C)(C)O2 +CC(=O)Nc1ccc(F)c(NC(=O)NCc2cc(F)ccc2F)c1 +CCCCN(C(=O)c1ccco1)c1c(N)n(CCC)c(=O)[nH]c1=O +Cc1nc(-c2ccccc2)sc1C(C)NC(=O)Cn1cnnn1 +CS(=O)(=O)N1CCC(C(=O)NCCOc2cccc(F)c2)CC1 +Cc1noc(C)c1C(=O)NC(Cc1ccsc1)c1cccnc1 +CC(C)c1nc(CNc2ccccc2CC(F)(F)F)no1 +CCc1onc(C)c1NC(=O)CCc1ccc(C(=O)OC)cc1 +CNC(=O)c1cc(NC(=O)CCNC(C)=O)ccc1Cl +Cc1ccnc(Nc2nc(C)c(C(=O)NCC3CCCO3)s2)c1 +COc1ccc(C)cc1NC(=O)NCc1ccco1 +CCNC(=O)NC1(C(=O)N2CCN(C(C)COC)CC2)CCCC1 +OCCCOC1CCN(Cc2cnc(-c3cccs3)s2)CC1 +O=C(NC1CC1)c1nc2c(o1)CN(C(=O)c1cccc(F)c1)C2 +COC(=O)N1CCC2(CC1)CNc1ccc(C)cc12 +CC(C)(C)c1nnc2n1NC(c1ccccc1)CS2 +O=C(Nc1cccnc1N1CCOCC1)c1cccs1 +COc1ccc2oc(-c3cc(-n4cnnc4)ccc3O)nc2c1 +O=C(CCc1ncc(-c2ccccc2)o1)NCCO +O=C(CCn1ccccc1=O)NCC1CCOc2ccccc2C1 +Cc1ccc(C)c(OCc2nc3ncc(N)cc3[nH]2)c1 +Cc1nc(-c2ccccc2)ccc1C(=O)N1CCN(C(=O)C2CC2)CC1 +Cc1nc(C2CCCN(C(=O)Cn3ccccc3=O)C2)sc1C +Cc1cc(=O)c(C(=O)NCCc2ccccc2)nn1-c1ccccc1 +CC(=O)c1cccc(NC(=O)c2c(C)cc(=O)oc2C)c1 +COc1cc(N)ccc1NC(=O)COc1ccccc1 +Cc1cc(-c2ccccc2F)nc(C2CCN(S(C)(=O)=O)CC2)n1 +Cc1ccc(S(=O)(=O)NCc2nc(C)cs2)cc1 +O=C(COc1ccc(F)cc1Br)Nc1nccs1 +COc1ccc(C2CC(=O)c3ccccc3O2)cc1 +N#Cc1ccc(C(N)c2nnc(-c3ccco3)o2)cc1 +Cc1cc(C(=O)Nc2ccc3c(c2)COC3)c(C)n1Cc1ccccc1 +CC1(C)CN(C(=O)Nc2ccccc2OC(F)F)CCO1 +Cc1cnc(NC(=O)Cn2ccc3ccc(F)cc32)s1 +Cc1ccc2oc(C(=O)NCc3ccccc3)nc2c1 +Cc1cc(C)n(CC(C)NS(=O)(=O)Cc2cccc(F)c2)n1 +CC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2)cc1 +COCCNC(=O)CCNC(=O)c1ccccc1F +CCOc1cccc(CNC(=O)c2ccc(N3CCOCC3)cc2)c1 +Cc1cc(NCCc2c[nH]c3ccccc23)cc(=O)n1CCO +CCOC(=O)CNC(=O)c1ccc(C(N)=O)cc1 +COC(=O)Nc1cc(NC(=O)C2(c3ccccc3)CCC2)ccc1F +Cc1occc1C(=O)NCC12CC3CC(CC(C3)C1)C2 +Cc1ccc(NC(=O)CSc2nnc(C)c(C)n2)cc1Cl +CCOCCn1c(C(C)NC(=O)c2ccccc2)nc2ccccc21 +Cc1n[nH]c(C)c1-c1c(C#N)c(N)nc2c1Cc1c(O)cccc1-2 +O=C(c1ccc(N2CCOCC2)cc1)N1CCCC(n2cccn2)C1 +Cn1c(CCNCc2cccc(O)c2)nc2ccccc21 +CN1C(=O)COc2ccc(COC(=O)CNC3CC3)cc21 +COC(=O)CCC(=O)NCC(C)(C)c1ccc(Br)cc1 +CC1CCC(NC(=O)C2(c3ccccc3)CCC2)CC1 +NC(=O)c1cc(S(=O)(=O)NCCc2ccco2)cs1 +N#Cc1ccc(CN2C(=O)COc3ccccc32)cc1 +CN(C)c1cccc(-c2ccc(CO)cc2CO)c1 +Nc1ccc(-c2cc(-n3cccn3)ccc2F)cc1 +CN(C)C(C(=O)NCCC(=O)NC1CCCCC1)c1ccc(F)cc1 +COc1ccc(C)cc1C(C)NC(=O)N(C)CC(O)C(F)(F)F +COc1ccccc1C(NC(=O)C#Cc1ccccc1)c1ccccn1 +CCOc1cccc(CN(C(=O)Cc2c(O)n[nH]c2C)C2CC2)c1 +Cc1cc(C(=O)COC(=O)Cc2coc(-c3ccccc3)n2)c(C)[nH]1 +O=C(CCn1cnc2c([nH]c3ccccc32)c1=O)NCc1ccccc1 +COc1ccc(S(=O)(=O)Nc2c(O)cccc2F)cc1Cl +C#CCN(CC#C)C(=O)c1cc(C2CC2)nc2ccc(Cl)cc12 +CCC(C)Nc1ncc(Br)cc1C#N +Cc1cc(C)nc(SCc2ccccc2C#N)n1 +Cc1ccc(NCC(=O)NC(C)(C#N)C(C)C)cc1-n1nnnc1C +Cc1noc(C)c1Cn1nnc(S(=O)(=O)C(C)C)c1N +CC(CC#N)N(C)C(=O)Nc1ccc(Oc2ccccc2)cc1 +Cc1cc(NCCC(=O)NC(C)C)n2nc(-c3cccnc3)nc2n1 +OCC(O)CSc1nnc(-c2ccccc2)o1 +CCCS(=O)(=O)NC(C)C(=O)NCC1CC=CCC1 +CNC(=O)CN1C(=O)COc2ccc(C(C)(C)C)cc21 +Cc1cc(C(=O)NCc2cn3c(n2)SCC3)c2c(C)noc2n1 +Cc1ccc(C)c(OCC(=O)N(C)CC(C)O)c1 +CC(C)c1ccc(OCC(=O)NCc2ccncc2)cc1 +CC(Sc1nccn1C)C(=O)N(C)c1ccccc1 +CC(=O)N1CCN(C(=O)NCCc2ccccc2)CC1 +CC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2cc(Cl)ccc2N)c1C +O=C(NC1CCCN(c2ccccc2F)C1)c1ccoc1 +O=C(Cc1c[nH]c2ccccc12)NC(CO)Cc1ccccc1 +O=C(c1ccc(NC2CC2)nc1)N1CCCN(c2ncccn2)CC1 +CCc1cnc(N)nc1N1CCC(Oc2ccc(F)cc2)CC1 +CCC1CN(C(=O)c2cc(C)no2)CCC(=O)N1Cc1ccccc1 +Nc1cc(C(=O)NC2CCCCNC2=O)ccc1Cl +CCNC(=O)c1ccc(C)c(NC(=O)CC2C=CCC2)c1 +O=C(c1ccoc1)N1CCC2OCCC2(COc2ncccc2F)C1 +Cc1nc(C)c(CNC(C)C(=O)NC(C)(C)C)s1 +CCn1cc(C(=O)NCc2ccccn2)c(=O)c2cc(Cl)ccc21 +COC(=O)C1NCC(C)(C)c2cc(F)cc(F)c21 +CC1CCCCC1NC(=O)NCCC(=O)NC1CCCCC1 +CCCNC(=O)CN(C)C(=O)Nc1ccc(Cl)c(Cl)c1 +CC1CCCN(C(=O)C(C)NS(=O)(=O)c2ccccc2F)C1 +CCOC(=O)CCCn1c(=O)[nH]c2ccccc2c1=O +Cc1sc(N)nc1-c1cc(Cl)c2c(c1)C(C)C(=O)N2 +O=C(c1cc2ccccc2[nH]1)N1CCN(Cc2ccc(F)cc2)CC1 +CC(C)CC(C)OCCC(=O)N1CC(=O)N(C)c2ccccc21 +CC(C)c1cc(NCCc2nc(-c3cccnc3)n[nH]2)n2nccc2n1 +Nc1ccc(F)c(NC(=O)C23CC4CC(CC(C4)C2)C3)c1 +Cc1cc(C)n(-c2ccc(SCc3ccccn3)nn2)n1 +COc1ccccc1COc1cc(NC(=O)c2cnccn2)ncn1 +Cc1occc1CN(C)C(=O)C(C)Sc1nnnn1C1CC1 +CC(c1ccccc1)N1CC(C(=O)NCc2ccncc2)CC1=O +Cc1ccc(CN(C)C(=O)c2cnc3ccccn3c2=O)c(C)c1 +Cn1c(C(F)(F)F)nc2cccc(C(=O)C3CC3)c21 +CCS(=O)(=O)N1CCC(C(=O)Nc2ccccc2OC)CC1 +COC(=O)c1ccc(NCc2nnc(C3CC3)o2)cc1Cl +COC(=O)c1cccc(NC(=O)c2[nH]c(C)c(C(=O)OC)c2C)c1 +CCN1C(=O)C(C)(C(=O)NCC(=O)NC)Oc2ccccc21 +Cc1c(C(=O)NCCc2ccc3c(c2)OCCO3)cnn1C +Nc1ccc2c(c1)N(C(=O)Cc1cccs1)CC2 +COCCN1CCN(C(=O)C(C)(C)c2cccc(Cl)c2)CC1=O +COc1ccnc(NC(=O)Cc2coc(-c3cccs3)n2)c1 +COC(=O)c1n[nH]c(N)c1-c1ccc(OC)c(C(C)C)c1 +CC(C)c1nnc2n1CCN(C(=O)c1cc(-c3ccco3)[nH]n1)C2 +CC(C)CC(C)NC(=O)C(O)C(O)c1nc2ccccc2s1 +O=C(Nc1cccc(N2CCCCC2=O)c1)c1cc2ccccc2[nH]1 +O=C(NCC1CC1)C1CC2CN(c3ncccn3)CC2C1 +Cc1cc(C)cc(C(=O)Nc2ccsc2-c2nnc(C3CC3)o2)c1 +COC(=O)c1ccccc1SCc1csc(C)n1 +CCn1ncc(CNC(=O)c2c(N)cnn2CC)c1C +CCc1cccc(C)c1NC(=O)CS(=O)c1ccc(C)cn1 +Cc1nn(C(C)C)c(C)c1NC(=O)c1ccnn1C +Cc1cc(C)c(C(=O)OC(C)COc2ccccc2)c(=O)[nH]1 +CCN(CC)C(=O)c1ccccc1NC(=O)CN(C)c1ccccc1 +COc1ccc(CN(C)C(=O)c2cc(C)no2)cc1 +CCOCC(=O)N(C)Cc1ccc(C(=O)OC)cc1 +Cc1ccc(CNC(=O)N2CCCC(CN3CCOCC3)C2)cn1 +CCn1ncc(-c2ccc(OC)c(C(C)C)c2)c(C#N)c1=O +CCCCCNC(=O)c1cnn2c(-c3cccc(F)c3)ccnc12 +CS(=O)(=O)c1cccc(NCc2ccccn2)c1 +O=C(NCCCC1CCOC1)Nc1cccc(C(F)(F)F)c1F +CC(C)c1nc(CC(=O)NC(C)c2csc(C(C)C)n2)cs1 +CC1c2cc(F)ccc2CCN1C(=O)CC1(O)CCCC1 +Cc1ccc(C(C)NC(=O)Nc2ccc(C#N)cc2)o1 +CC1(C(=O)NC2CCCCC2)Oc2cccnc2NC1=O +O=C(NCCn1cccc1)c1cc2n(n1)CCCO2 +COCC(=O)N1CCN(Cc2ccc3ccccc3n2)CC1 +c1cnc(Nc2nc(-c3ccc4c(c3)OCCCO4)n[nH]2)nc1 +CC(NC(=O)CCOc1cccc(N)c1)c1ccccc1 +CC(C)CC(C)OCCC(=O)Nn1cnc2ccccc21 +C=CCN(CCc1nc2ccccc2c(=O)[nH]1)Cc1cccc(C#N)c1 +O=C(NCCOc1ccccc1)c1ccc(-c2cnco2)cc1 +COCCN1CC(NC(=O)c2nccn2C)C2OCCCC21 +N#CCC(COc1ccccc1F)N1CCCCC1 +COC(=O)c1cc(NC(=O)c2ccc(-n3ccnc3)nc2)ccc1F +O=C(Nc1nc[nH]n1)c1cccc(S(=O)(=O)NC2CC2)c1 +COc1ccc2cc(CNc3ccc(O)cc3)c(=O)[nH]c2c1 +CCCC(NC(=O)C1CCC(=O)NC1)c1ccc(Cl)c(Cl)c1 +COc1ccc(NC(=O)c2c(Cl)cnn2C)cc1 +Cc1ccc(OC(=O)CCc2cnn(C)c2)c(Br)c1 +CC(C)C(C)N(C(=O)c1ccc(-n2cnc3ccccc32)nc1)C1CC1 +O=C(NCCc1nc2ccccc2[nH]1)c1ccccc1-n1cnnn1 +Nc1c(-c2nc(-c3ccncc3)no2)nnn1-c1ccccc1F +CC(C)Cn1c(N)c(NCc2nncn2C)c(=O)[nH]c1=O +Cc1ccc(S(=O)(=O)NCC#CCN2CCOCC2)cc1C +CCOC(=O)c1ccc(NC(=O)NC(CC)c2cnn(C)c2)cc1 +CCCC(C(=O)OC)c1ccc(OC)c(OC)c1 +CC(C)n1cc(NC(=O)NC2CC(=O)Nc3ccccc32)cn1 +Cn1ccnc(NC(=O)c2cccc3c2OCO3)c1=O +CCOc1ccc(NS(=O)(=O)c2cn[nH]c2)cc1CO +CC(C)c1ccc(NC(=O)NCc2ccc(Cn3cncn3)cc2)cc1 +Cc1cc(S(C)(=O)=O)ccc1NCc1ccccc1 +c1ccc(-n2nnnc2SCc2nnc3n2CCCCC3)cc1 +N#Cc1cc(NC(=O)C2(c3ccc(F)cc3)CCOCC2)ccc1F +Brc1cccc2[nH]c(-c3ccncc3)cc12 +Cc1ccc(CC(=O)NCCNc2ncccn2)s1 +COC(C)C(=O)Nc1cc(Br)ccc1N1CCOCC1 +CCc1ccc(-c2ccc(C#N)c(=O)n2CC)cc1 +CCOc1cc(Br)c2sc(NC(=O)CC#N)nc2c1 +CC(=O)c1ccc(N2CCN(Cc3ccc(O)cc3)CC2)cc1 +COC(=O)c1c(C)nc(C)c2c(=O)n(-c3nc(C)n[nH]3)ccc12 +COc1cccc(C(N)c2nc(C)cs2)c1OC +CCN1CC2CN(C(=O)Nc3ccccc3C)CC(C1)O2 +Cc1ccccc1S(=O)(=O)n1cc2c(=O)n(C)c(=O)n(C)c2n1 +CCS(=O)(=O)Nc1n[nH]c(C)c1-c1cccc(Br)c1 +CCn1ncc2ccc(NC(=O)c3cnc(C)cn3)cc21 +Cc1cccc(C(=O)NCc2cccc(CN3CCCC3=O)c2)c1C +COc1cccc(C(=O)Nc2ccc3c(c2)N(C)C(=O)CO3)c1F +CC(=O)Nc1nc(C(=O)OCc2ccccc2)cs1 +Fc1cc2ncnc(Sc3nnc(C4CC4)n3C3CC3)c2cc1F +CCN1CC(C(=O)NCc2cc3c(cc2OC)OCCO3)CCC1=O +CCn1nnc(NC(=O)c2cc(Br)cc(C)c2OC)n1 +COC(=O)CN(Cc1nc2c(s1)CC(C)CC2)C(C)C +O=C(CNC(=O)c1ccccc1Cl)c1cccs1 +O=C(COc1ccc(Cl)cc1)N1CCN(C(=O)c2cc[nH]n2)CC1 +CNC(=O)C(C)NS(=O)(=O)c1ccc(F)cc1 +COC(=O)c1ccc(C(=O)Nc2ccc3oc(C)nc3c2)cc1 +COc1ccc(C)cc1C(C)NC(=O)CC1C=CCC1 +COc1cccc(CNC(=O)CNC(=O)c2ccc3ncnn3c2)c1 +CCn1c(=O)c(C(=O)NCc2ccncc2)nc2cccnc21 +O=C(C1CCCCC1)N1CCN(c2ccccc2O)CC1 +Cc1cc2cc(NC(=O)c3ccc4c(c3)OCO4)ccc2[nH]1 +CCc1noc(CC)c1CC(=O)Nc1ccc(C(=O)NC2CC2)cc1 +CCn1c(C)cc(C(=O)N2CCCC(NS(C)(=O)=O)C2)c1C +CC1CCOC1C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +Cc1nc(C)c(CC(=O)NCCCC(C)C)c(=O)[nH]1 +NC(=O)c1ccc(-n2nnnc2-c2ccc(N)cc2)cc1 +CN(CCOCC1CC1)C(=O)C1CCN(C(=O)c2ccoc2)CC1 +CN(Cc1ccccc1)C(=O)c1c[nH]c2ccccc2c1=O +O=C(NCc1ncc2c(n1)CCC2)c1c[nH]nc1C1CCCCC1 +CC1COCC(C)N1C(=O)c1cc(S(C)(=O)=O)ccc1Cl +C=CCN(CCO)S(=O)(=O)c1c(C)c(C)cc(C)c1C +CCNC(=O)c1ccc(NC(=O)NCc2ncn(C)n2)cc1 +CC(C)c1ccc(C(=O)CCC(=O)N2CCN(C)CC2)cc1 +COCCCn1cnc2sc(C)c(C)c2c1=O +COC(=O)Nc1cccc(NCc2nc3ccccc3n2C(C)C)c1 +NC(=O)COc1cccc(NC(=O)c2cccc(-c3ccoc3)c2)c1 +CS(=O)(=O)N1CCCC(c2nnc(-c3cccs3)o2)C1 +CS(=O)(=O)c1ccccc1C(=O)Nc1ccc2c(c1)OCCCO2 +COc1cc(NC(=O)c2nc[nH]n2)cc(OC)c1OC +Cc1cc2nc(C)c(CCC(=O)N3CCOCC3)c(C)n2n1 +Cc1nc(CN2CC(=O)N(C)c3ccccc3C2=O)no1 +Cc1cccc(C)c1OCC(=O)Nc1ccc(-n2cnnn2)cc1 +Cc1cc(CN(C)C(=O)NCc2ccc(OC3CCCC3)nc2)no1 +CCC(C)NC(=O)Nc1ccc(OC)c(-n2nnnc2C)c1 +OCc1cccc(OCCCOc2ccc3c(c2)OCO3)c1 +CN(C(=O)CNC(=O)c1sc2ccccc2c1Cl)C1CC1 +O=C(Cc1cccc(O)c1)Nc1cnn(-c2ncccc2Cl)c1 +N#CCc1cccc(C(=O)NC2CCN(C(=O)c3ccoc3)CC2)c1 +Cc1ccc(-c2nnc(SCC(=O)NCC(C)C)n2C)cc1 +CC(C)(C)C(C#N)NC(=O)COc1ccc(CC(N)=O)cc1 +CC(C)(C)OC(=O)CSc1nnc(Cn2cncn2)o1 +CN(C(=O)Cc1ccc[nH]1)C1CCN(c2ccccc2Cl)C1=O +CC(C)C(=O)N1CCC(NC(=O)Cc2noc3ccccc23)CC1 +O=C(Cc1ccc(N2CCNC2=O)cc1)Nc1cnc2n1CCCC2 +CNc1snc(C)c1C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +CCOC(=O)C1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +Cn1cc(S(=O)(=O)N2CCOC(c3ccccn3)C2)cn1 +COc1ccccc1-c1c2c(=O)n(C)ccc2nc2ncnn12 +O=C(CNC(=O)c1ccsc1)NCCc1ccc(Cl)cc1 +CC(C)(C)OC(=O)NC1(CNC(=O)Cc2ccc[nH]2)CCCCC1 +COCCCNC(=O)c1nnn2c1nc(N)c1c(Cl)cccc12 +CCc1ccc(CNC(=O)CN2C(=O)COc3ccccc32)cc1 +COC(=O)Cc1nc(NC(=O)c2ccc(OC)cc2)sc1C +O=C(Cc1c[nH]c2ccc(Cl)cc12)N(CCO)Cc1cccnc1 +Cc1n[nH]c(SCCNCc2cc(=O)c3cc(F)ccc3[nH]2)n1 +N#Cc1ccc(NC(=O)Cc2ccc(-n3cnnn3)cc2)cc1Cl +CCCc1nnc(NC(=O)Cn2ccc3c(Cl)cccc32)s1 +CC(C)(C(=O)Nc1cccc(C#N)c1)c1ccc(N)cc1 +CC(CO)NC(=O)Nc1cccc(C(=O)N2CCCC2)c1 +O=C(CSc1nc2[nH]cnc2c(=O)[nH]1)c1ccc2c(c1)OCCO2 +COc1ccc(OCC(=O)N(C)Cc2ccc3c(c2)OCCO3)cc1 +CC(=O)c1cccc(NC(=O)C(O)c2ccc(C)cc2)c1 +CS(=O)(=O)c1ccc2nc(C3CCCCO3)[nH]c2c1 +COCC(C)NC(=O)Cc1c(C)nc2nc(SC)nn2c1C +C1CCCN(c2nc3nonc3nc2NCC2CCCO2)CC1 +CC(C)c1noc(CN2CCN(C(=O)c3ccc(=O)n(C)n3)CC2)n1 +COCc1c(CO)oc2cc(C)c(Cl)c(C)c12 +Cc1cc(-c2cnc(N3CCCC(O)C3)nc2C2CCCO2)on1 +CC(NC(=O)CSc1n[nH]c(N)n1)c1ccc(Cl)cc1 +O=C(Nc1ccncc1)c1ccc(Cn2cccn2)cc1 +CC1COCCN1CC(=O)NCCOc1ccc(C(F)(F)F)cc1 +COc1cc2c(cc1OC)C(C(Cl)(Cl)Cl)OC(=O)C2 +Cn1cc(CC2CCN(C(=O)c3c[nH]c4cccc(F)c34)C2)cn1 +N#CCc1ccc(NC(=O)CCc2ccco2)cc1 +Cc1c(C(=O)N(C)Cc2ccc3c(c2)OCCO3)oc2ccccc12 +Cc1ccccc1NCC(=O)Nc1ccc2c(c1)OCO2 +Cc1cc(C2CCCN2C(=O)c2ccccc2F)on1 +Cc1ccn2ncc(C(=O)NCCNC(=O)Cc3ccccc3)c2n1 +CC(C)N(C)C(=O)NCc1cccc(OCCN2CCOCC2)c1 +CCn1nc(C)c(NC(=O)c2nnsc2C)c1C +CC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCN(C)CC2)c1 +CNC(=O)c1ccc(NC(=O)c2ccc(C)c(OC)c2)cc1Cl +CC(CO)NC(=O)CCc1ccc(C(C)(C)C)cc1 +Nc1ccc2c(c1)C(=O)CC(c1ccc(F)cc1)O2 +CS(=O)(=O)N1CC(NC(=O)c2ccc(N)nc2)C(C2CC2)C1 +CSc1ncc(C(=O)NCC(C)O)n1-c1ccccc1 +CCOC(=O)c1ccc(NC(=O)C(C)n2c(N)nnc2SC)cc1 +O=C(Cc1c[nH]c2ccccc12)NC(c1ccccc1)c1ccccn1 +Cc1cc(C(=O)NCCOc2ccccc2)c(C)n1C(C)C +CCC(C)(C)C1CCCN1C(=O)c1ccc(-n2ccnn2)cc1 +O=C(NCC1(c2ccc(F)cc2)CCC1)N1CCC2(C1)OCCO2 +CCn1c(N)nc2cc(C(=O)NCCc3cccnc3)cnc21 +Cc1c(C(=O)c2cccc(N)c2)ccc2[nH]ncc12 +CCC(Oc1ccc2c(c1)CCC2)C(=O)Nc1ccon1 +CCCC(=O)Nc1cccc(NC(=O)NC(C)c2ccncc2)c1C +NC(=O)c1cccc(S(=O)(=O)N2CCCCCC2)c1 +Cc1csc(NC(=O)CSc2cccc(Cl)c2)n1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)c1cc(-c2ccco2)on1 +Cc1cc(Br)ccc1OCn1nc(N)cc1C +Cc1sc2nc(SCC3CCCO3)n(C)c(=O)c2c1C +CC1CCCCN1C(=O)CNC(=O)c1cc(-c2ccccc2)on1 +Cc1cc(C(=O)N(C)Cc2ccc(Br)cc2)c(C)o1 +CN(C)C(=O)c1ccc(CSc2nc(-c3cccs3)n[nH]2)cc1 +COC(=O)c1cccc(C(=O)N(C)C2CCc3ccccc3C2)c1 +O=C(NCCC(O)c1cccs1)NCc1ccc(F)cc1 +Cn1c(=O)n(CCC(=O)NCCc2ccc(O)cc2)c2ccccc21 +CCOc1ccc(F)c(C(=O)Nc2scnc2CC)c1F +CCc1nc2n(n1)CCCC2NC(=O)c1ccccc1Br +COc1cccc(CCNC(=O)NCC(C)(C)C(N)=O)c1 +Cc1nc(C)n(CC(=O)Nc2ccc(C(=O)N(C)C)cc2)n1 +COCCn1cc(NC(=O)N2CCCC2)c2ccccc21 +CCCC(=O)Nc1cccc(NC(=O)C2CCOCC2)c1 +O=C(Nc1ccc(F)c(Cl)c1)C(c1ccccc1)n1cnnn1 +COc1ccc(C(=O)Nc2cccc(N)n2)cc1OC +NC(=O)COC(=O)c1cc(F)ccc1-c1ccccc1 +CN(CC(=O)NC1CC1)C(=O)CCc1cc(F)ccc1F +Cc1nc(C(=O)NC(C)COc2c(C)cccc2C)cs1 +CCOCCN1Cc2nnn(CC)c2C(COC)C1 +Cc1nc(-c2cccs2)sc1CNC(=O)NC(C)(C)C +Cc1ccccc1C(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +CCCNC(=O)c1cccc(NC(=O)N(C)Cc2ccncc2)c1 +COCCNC(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1C +CCNC(=O)c1cccc(NC(=O)NCCC(C)C)c1 +C#CCn1c(C2CC(=O)N(c3cccc(C)c3C)C2)nc2ccccc21 +Cc1cc(C(NC(=O)c2cn(CC(N)=O)nn2)C(C)C)c(C)s1 +Cc1cccc(-c2nc(-c3cc4ccccc4[nH]c3=O)no2)c1 +O=C(COCC1CCCO1)Nc1cc(-c2ccccc2F)no1 +COCC(=O)Nc1ccn(-c2ccc(Cl)cc2Cl)n1 +CC(=O)NC(Cc1ccccc1)c1nc2ccccc2[nH]1 +O=C(Cc1csc(N2CCCC2=O)n1)Nc1cc(F)cc(F)c1 +CC1CN(C(=O)OC(C)(C)C)CCN1c1cnc2ccccc2n1 +Cc1ccc(O)c(S(=O)(=O)Nc2ccccc2C(N)=O)c1 +CCC(CC)C(O)CNC(=O)NCc1cc(C)on1 +O=C(c1ccnc(-n2ccnc2)c1)N1CCN(Cc2ccncc2)CC1 +CCn1ccc(C(=O)Nc2nc3c(C)ccc(C)c3s2)n1 +CN(C)C(=O)c1ccc(-c2ccccc2Br)o1 +Cc1ncsc1COC(=O)C(C)N1CCc2ccccc2C1 +Nc1ccccc1CCC(=O)N1CCN(c2ccccc2F)CC1 +N#Cc1c(N2CCN(C(=O)c3ccoc3)CC2)nc2ccccn12 +COC(=O)CC1CN(Cc2ccc(C3CC3C)o2)CCO1 +Clc1ccc(-n2ncc3c(N4CCCCC4)ncnc32)cc1 +Cc1ccc2cc(CCNC(=O)C3CCCCC3)c(=O)[nH]c2c1 +O=C(COc1ccccc1)N1CCCC1c1ccc(F)cc1 +COc1ccnc(NC(=O)c2cnn(-c3ccccc3)c2C)c1 +CCC(=O)c1ccccc1OS(=O)(=O)c1ccc(C#N)cc1 +CS(=O)(=O)NCc1cc(C#CCO)ccc1F +CCNC(=O)CNC(=O)CN1C(=O)CCOc2ccccc21 +CCOC(=O)C(C)Sc1nnc(-c2c[nH]c3ccccc23)n1C +Cc1nc2c3ccccc3nn2c(C)c1CCC(=O)OCC(N)=O +CNC(=O)NCC(=O)N1CCCCCC1c1ccco1 +CSc1nc(C)cc(C(=O)NCc2ccc(C)o2)n1 +N#Cc1cc2c(nc1SCC(=O)Nc1ccc(F)cc1)CCC2 +Cc1ccc2[nH]nc(C(=O)Nc3ccc(CC(N)=O)cc3)c2c1 +NC(=O)Cn1ccn2nc(-c3ccc(Cl)cc3)cc2c1=O +NC(=O)c1ccc(NC(=O)c2csc(-c3ccccc3)n2)cc1 +CN(Cc1nc2c(cnn2C)c(=O)[nH]1)Cc1csc2ccccc12 +Cc1cc(=O)n(C)cc1NC(=O)N(Cc1ccccc1F)C1CCC1 +CCn1nnc2cc(C(=O)Nc3ccc(NC(=O)C4CC4)cc3)ccc21 +O=C1CCC(C(=O)NCCCOCC2CCCO2)N1 +COC(=O)Cc1c(C)c2ccc(OCC(=O)NC3CC3)cc2oc1=O +CCOc1cc(S(=O)(=O)NC(C)CC)ccc1Cl +CCN1CCN(C(=O)CN2C(=O)CCCc3ccccc32)CC1 +CCOCc1cccc(CNC(=O)NC2CCCC2)c1 +CC1CCCC(C)N(C(=O)c2ccc(OCC(F)F)nc2)C1 +Cc1oc(-c2ccccc2)cc1C(=O)NCc1ccncc1 +O=C(CCOc1ccc(F)cc1)N1CCOCC1C1CC1 +COCCC1(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)CCC1 +CCN(CC)C(=O)C1CCN(c2ccc(-c3cccs3)nn2)CC1 +CCc1cnccc1CNC(=O)Nc1ccccc1OC1CCOC1 +CC(NS(C)(=O)=O)C(=O)Nc1ccccc1-c1ccccc1 +COC(=O)c1ccc(N(C)Cc2cc(F)c(F)c(F)c2)nn1 +O=C1CCN(S(=O)(=O)c2cccc(Br)c2)CCN1 +CCOC(=O)C1CCC(=O)N1c1cccc(OC)c1 +CNc1ncc(C(=O)N(CC(C)C)C(C)C)cc1Cl +Cc1ccc(CC(=O)N2CCCC3(CCC(=O)N(CCO)C3)C2)cc1 +CN(CC1COc2ccccc2O1)C(=O)C(C)(C)C +COCC(O)CN(C)C(=O)c1ccc(OC)c(N)c1 +Cn1nc(N2CCC(C(=O)Nc3ccon3)CC2)ccc1=O +CC(=O)Nc1ccc(CC(=O)OCc2nc3ccccc3[nH]2)cc1 +COC(=O)CCCC(O)c1ccc(C(C)C)cc1 +C=CCCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CC(C)c1ncc(C(=O)OC(C)c2ccccn2)s1 +NC(=O)c1ccc(OCc2nnnn2C2CC2)cc1 +Cn1nnnc1SCCNC(=O)Nc1cccc2c1CCCC2 +CCCn1cc(S(=O)(=O)c2ccccc2)c(=O)c2cc(C)ccc21 +Cc1onc(-c2ccccc2Cl)c1C(=O)NCCCOC(C)C +O=C(Nc1cc(-c2ccco2)no1)c1cccs1 +O=C(Nc1nc2c(s1)COCC2)c1cnc2ccccc2n1 +CCn1c(SCC(=O)NC(C)CO)nnc1-c1cccc(C)c1 +O=C(NC1CC1)c1nc(-c2ccc(F)c(F)c2F)cs1 +CC(=O)NC1CCCN(C(=O)c2csc(-c3ncccn3)n2)C1 +O=C(Nc1ccc2c(c1)OCCO2)c1cccnc1Oc1ccccc1 +CCCN(C)c1ccc(C(=O)NCc2ncn(C)n2)cc1 +Cc1ncc(CNC(=O)NC(C)CCCC(C)C)s1 +O=C(COc1ccccc1F)Nc1cccc(NC(=O)C2CC2)c1 +COC(=O)c1n[nH]c2ccc(NC(=O)COc3cc(C)on3)cc12 +Cc1ccccc1OCC(=O)NCCc1ccsc1 +N#CCCC(C#N)CN1CCN(S(=O)(=O)c2cccnc2)CC1 +COC(=O)c1cccnc1N1CCC(=O)N(CC2CC2)C(C(C)C)C1 +CS(=O)(=O)N1CCCC(C(=O)NCC2CC2)C1 +CCCOc1cc(C)ccc1NC(=O)c1ccccc1-n1cnnn1 +O=C(CCOCC1CCCO1)N1CCN(c2ccccc2O)CC1 +CC(C)(C)NC(=O)CNC(=O)N1CCCC1c1ccccc1 +CC(NC(=O)c1ccc2noc(-c3ccccc3)c2c1)c1ccncc1 +Cc1nn(C)c(C)c1NC(=O)COc1ccc(C#N)c(F)c1 +CNC(=O)CN1CCN(C(=O)c2sccc2C)CC1 +CC(=O)N1CCCC1C1NCCc2ccc(F)c(C)c21 +COc1ccccc1-c1cc(NC(=O)c2ccoc2C)[nH]n1 +Cc1ccc2cc(C(=O)N3CC(CO)OCC3C)ccc2n1 +Clc1cccc(-c2nc(CN3CCOCC3C3CC3)no2)c1 +CCN(Cc1cnn(C)c1)c1cnc2ccccc2n1 +CC(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)Nc1cc(Cl)ccc1F +CCCNC(=O)CN(CCC)C(=O)c1cc2c([nH]c1=O)CCCC2 +COc1ccc(Cl)cc1NCC(=O)Nc1cnn(CC(N)=O)c1 +CC(C)N(CCCO)C(=O)c1cc(F)c(Cl)cc1Cl +Cc1nc(CNc2c(C)cccc2OC(F)F)cs1 +Cc1cc(C)c2c(NCCc3nc(C(C)C)no3)ncnc2n1 +Cc1occc1C(=O)N1CCC2(CC1)CC(OCC1CC1)CO2 +COc1ccc2c(c1)nc(C1CC1)n2Cc1cccnc1 +COCC(C)(O)CNC(=O)c1cc(-c2ccccc2)on1 +Cc1csc(CNC(=O)c2ccc(COC(C)C)cc2)n1 +NC(c1ccc(O)c(F)c1)c1nc2c(s1)CCCC2 +CC(C)c1n[nH]c(C2CN(Cc3ccn(C(C)C)n3)CCO2)n1 +CC(NC(=O)Nc1ccccc1)C(=O)N(C)CCOc1ccccc1 +CCCOc1ccc(-c2c(C#N)c(N)n(N)c(=O)c2C#N)cc1 +Cc1nc(SCCC(C)C)c2c(=O)n(C)c(=O)n(C)c2n1 +COc1cccc(CN2CCN(C(=O)c3cccnc3)CC2)c1OC +CCCn1nnnc1COc1c(Cl)cccc1Cl +CC1C(=O)N(C)CCN1c1nc2nonc2nc1NC1CCCC1 +Cc1cc(-c2nn3c(-c4cnccn4)nnc3s2)on1 +NC(=O)C1CCCN1C(=O)C1CC(=O)N(c2ccccc2Cl)C1 +CC(C)(CNC(=O)NCC1CN2CCCCC2CO1)C(N)=O +Cc1cc(-c2nnc(NC(=O)c3ccc(C#N)cc3)o2)c(C)o1 +COC(=O)c1sc2nc(-c3ccc(C)o3)[nH]c(=O)c2c1C +COc1ccc(C)c(NC(=O)NCc2ncc(-c3ccccc3)[nH]2)c1 +Cc1cc(-c2nnc(NC(=O)c3ccc4ccccc4n3)o2)c(C)o1 +CC(=O)N1CCN(C(=O)Cc2cn3ccsc3n2)CC1 +Cc1ccc(C(=O)NCc2ccc(Cn3cccn3)cc2)c(=O)[nH]1 +C=CCn1c(C)nnc1SCCn1c(=O)oc2cccnc21 +CCc1nc2sc3c(n2n1)CCNC3C(C)C +COc1ccc(S(=O)(=O)CC(=O)Nc2cccc(F)c2)cc1 +NC(=O)c1ccc(OC2CC2)cc1Br +Cc1ccc(NC(=O)Cc2ccc3c(c2)OCCO3)c(Cl)c1 +CS(=O)(=O)c1ccc2c(c1)nc(N)n2C1CC1 +O=C(Nc1ccc(-n2cnnn2)cc1)c1cccc(Cl)c1 +Cn1cnc(CNC(=O)c2c(O)cc(F)cc2F)n1 +O=C(c1c[nH]c2ccccc2c1=O)N1CCCCC1 +CCc1ccc(C(=O)COC(=O)c2cnccn2)cc1 +Cc1c(Br)cccc1CNc1ccc(C(N)=O)c(F)c1 +CN(C(=O)CCNC(=O)C1(c2ccccc2F)CC1)c1ccccc1 +Fc1ccc(NCc2csc(-c3ccccn3)n2)nc1 +C=CCn1c(C(=O)N2CCN(C(C)=O)CC2)cc2sc(C)cc21 +CC(C(=O)NCc1ccncc1)N1CCN(c2ccc(F)cc2)CC1 +Cc1ccc(C2Nc3ccccc3C(=O)N2Cc2ccco2)s1 +CC(C)N(CC(N)=O)C(=O)c1ccc(OCc2cscn2)cc1 +COC(=O)CNc1ccc(NC(=O)C2CCCO2)cc1C(F)(F)F +NC(=O)C1CCN(C(=O)Cc2c(F)cccc2Cl)CC1 +CCCOC1CCCN(c2cc(Br)ccc2CO)C1 +CC(NC(=O)NC1(C)CCC1)C(OC1CCOCC1)c1ccccc1 +CC1CN(C(=O)c2cccnc2Oc2cccnc2)CC(C)(C)O1 +CCOCCOc1ccccc1C(=O)N1CCCC(c2ncc[nH]2)C1 +COc1ccc2c3c(ccc2c1)CCNC3c1ccnnc1 +Cc1ccc(C)c(C(C#N)CCC(=O)NC2CC2)c1 +CCOc1ccc(Oc2ccccc2NC(C)=O)cc1 +Cn1cc(CCC(=O)Oc2cc(Cl)cc(Cl)c2)cn1 +Cc1cccc(NC(=O)c2cc3c(cc2O)OCO3)n1 +CCc1ncc(C(=O)NCc2cc(OC)ccc2OC)c(C)n1 +COc1cccc(Cc2nc3cccc(C)n3c2CO)c1 +Cc1nnc2ccc(C(=O)N(Cc3ccc(C#N)cc3)C(C)C)cn12 +CN(C)S(=O)(=O)c1ccc2nc(N3CCC(=O)CC3)cnc2c1 +CCCc1cn(CC2CCCN(c3nc(N)nc4[nH]ncc34)C2)nn1 +CCOc1cccc(NC(=O)c2cnn(-c3ccncc3)c2C)n1 +COc1cc(CNS(=O)(=O)c2cc(F)c(F)cc2F)ccn1 +CC(=O)Nc1ccc(-n2cnc(C(=O)NCc3ccco3)c2)nc1 +CCCCC(=O)NCCn1ccnc1-c1ncccn1 +CCN(CCNC(=O)N1CCCC(CO)C1)C(=O)OC(C)(C)C +Cc1[nH]n(-c2ccc(Cl)c(Cl)c2)c(=O)c1CCO +CN(Cc1ccncc1)C(=O)C1(c2ccc(Cl)cc2)CCC1 +COC1CCN(C(=O)c2ccncc2)CC1Cc1cccc(C)c1 +O=C(C1CCOCC1)N1CCc2ncnc(C3CCOC3)c2CC1 +COc1ccc(CC(C)CNC(=O)c2ccoc2C)cc1 +COc1ccc(-n2nc3cc(N)c(Cl)cc3n2)cc1 +COCC(C)NC(=O)NCc1ccc(C(=O)N(C)C)cc1 +O=C(Cc1cccnc1)N1CCCCC1CN1CCOCC1 +O=C(CC1CCCCC1)N1CCN(CCc2ccccn2)CC1 +CCCc1nnc(C(=O)N(C)Cc2noc(C)n2)o1 +O=c1c(-c2ccc3c(c2)OCO3)coc2cc(O)ccc12 +CN(CCCc1ccccc1)C(=O)NCC(C)(C)C(N)=O +CN(C)C(=O)C1CCN(C(=O)CCCOc2ccccc2)CC1 +Cn1ccnc1S(=O)(=O)CC(=O)Nc1ccc(F)cc1F +O=C(Cn1cc(-c2ccccc2)ncc1=O)Nc1ccncc1 +COc1ccc(C(=O)c2cccc(C3OCCO3)c2)cc1 +CNC(=O)COC(=O)c1csc(Cc2ccc(C)cc2)n1 +O=C(C1CC1c1cccc(Cl)c1)N1CCOCC1C1CC1 +CC(C)NC(=O)c1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1 +NC(=O)c1c(NC(=O)c2cnccn2)sc2c1CCCCC2 +Cc1ccc(S(=O)(=O)NCCC(=O)N2CCOCC2)s1 +CCC(C)C(=O)N1CCN(C(=O)Cc2ccccc2F)CC1 +CC1CCC(NC(=O)COc2cccc(-n3cnnn3)c2)CC1 +CC(C)(C)CC1NCCc2c(O)ccc(Br)c21 +COc1ccc(C(=O)Nc2cccc(CS(N)(=O)=O)c2)cc1 +COC(=O)C1CCCC1NC(=O)Nc1ccc(C(C)=O)c(C)c1 +CCC1COCCN1C(=O)NCc1ccnc(OC2CCC2)c1 +CCCCNC(=O)C(C)Sc1ncccc1Cl +Cc1cc(F)ccc1OC(=O)c1ncn(-c2ccccc2)n1 +Cc1ccc(C(=O)N2CCOCC2c2nc(C)no2)c(F)c1 +CCC(O)c1cc(Cl)c2c(c1)C(CC)C(=O)N2 +CC(=O)c1ccc(F)c(N2CCc3ccccc3C2)c1 +O=C(Nc1ccccn1)c1occc1-c1ccccc1 +Cc1n[nH]cc1NC(=O)COc1ccc(F)cc1Cl +O=C(NCCO)c1ccc(NCc2cccs2)cc1 +Nc1ccc(SCC(=O)Nc2ccccc2Br)cc1 +CC(C)c1n[nH]c(NC(=O)Cc2c[nH]c3ccccc23)n1 +CCOC(=O)c1cnc(SCCCO)nc1N +COC(=O)c1cc(C(=O)N2CCC(c3ccccc3)C(C)C2)ccn1 +Cc1cnc(C(=O)N2CCCC(CCc3c(F)cccc3F)C2)cn1 +O=C(NCc1cccc(OC(F)(F)F)c1)c1cccn2nccc12 +Cc1nn(C)c(C)c1NC(=O)C1CC(=O)N(C)C1c1ccc(F)cc1 +O=C(Nc1cc(-c2ccccn2)no1)C1CCCC1 +COCc1cc(CNC(=O)C2COc3ccccc3O2)n[nH]1 +Cc1csc(C(C#N)C(=O)CCSc2ccc(Cl)cc2)n1 +CNC(=O)C1Cc2ccccc2CN1Cc1nc(C2CC2)no1 +O=C(Nc1nnc(-c2ccncc2)s1)c1ccc(Cl)cc1 +C=CCCOC(C)C(=O)N1CCCC1c1ccc(OC)cc1 +Cc1sc(=O)n(CC(=O)NCc2ccc3c(c2)OCO3)c1C +Cn1ccnc1CSc1nnc(Cc2cccc(F)c2)o1 +CCOC(=O)c1nn(-c2ccccc2)cc1C(=O)c1ccco1 +CCCn1c(NCC(C)O)nc2sc3c(c2c1=O)CCCC3 +COCCOc1ccc(NC(=O)N2CCCC(C(F)(F)F)C2)cn1 +NC(=O)c1ccc(C(=O)NCc2ccccc2OC(F)(F)F)cc1 +CC(C)CCOC(C)C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +COc1ccc(C(=O)Nc2cc(N3CCC(C)CC3)ncn2)cc1 +CCOc1cc2c(cc1CNC(=O)C1CCCC1)OC(C)C2 +CC(C)C(=O)N1CCOCC1c1nccc(Nc2ccccn2)n1 +Cc1nnc(SC(C(=O)N(C)c2ccccc2)C(C)C)s1 +Cc1cc(NC(C)c2ccccc2-n2cccn2)n2nccc2n1 +COC(=O)c1ccc(Cn2c(C(C)C)ccc(C#N)c2=O)cc1 +Cc1noc(C)c1CC(=O)NCc1cccc(O)c1 +CC(C)N(C)S(=O)(=O)N(C)Cc1ccc2c(c1)OCCO2 +Cc1cc(C(C)NC(=O)c2cc(=O)c3ccccc3o2)c(C)s1 +CCc1c(C)[nH]c2c(Br)cccc2c1=O +COc1ccc2c(=O)cc(C(=O)Nc3cccc(C)c3)oc2c1 +O=C(C1CC=CC1)N1CCOC2(COCCN(c3ncccn3)C2)C1 +Fc1ccccc1OCCOn1nnc2ccccc21 +O=C(NCCCC(=O)N1CCOCC1)c1ccc2cc[nH]c2n1 +COc1cccc(C(=O)N2CCC(c3nc4cccnc4n3C)C2)c1 +Cc1cccc(C)c1-n1nnnc1SCCS(N)(=O)=O +Cc1nc2ccc(NC(=O)COc3ccccc3C)cc2o1 +CC(CNC(=O)Nc1ccc2ccccc2c1)N1CCOCC1 +N#Cc1nnn(-c2cccc(C(F)(F)F)c2)c1C1CC1 +CC(C)N(Cc1ccccn1)C(=O)c1cn2cccnc2n1 +O=C(NC1CC1c1ccccc1)c1cnc(-c2cccnc2)nc1 +COc1cccc(C(CNC(=O)NCc2ccc(F)cc2)OC)c1 +Cc1noc(C)c1CC(=O)N(C)c1ccc(S(C)(=O)=O)cc1 +CCOc1cc(NC(=O)c2cc3cccc(OC)c3o2)ccc1OC +COc1cccc(NCc2cc(C(N)=O)ccc2F)c1 +Cn1nccc1C(=O)Nc1nc2c(F)cccc2s1 +COc1ccc2c(c1)OCC(CNC(=O)c1cc(C(C)C)on1)C2 +CCC(C)n1ncc(C(=O)N2CCNC(=O)C2)c1C1CC1 +CCOCc1ccccc1NCC(=O)Nc1ccc(F)cc1F +CC(=O)N1CCN(c2nc(C)cnc2C)CC(O)C1 +CC(=O)Nc1ccc(NCC(=O)Nc2ccccc2F)cc1 +Cc1oc(C(=O)N2CCCCCC2CC(C)C)cc1S(N)(=O)=O +CC1Oc2ccc(NC(=O)COc3cccc(Cl)c3)cc2NC1=O +CCCC(=O)N1CCCC1c1nnc(-c2ccsc2)o1 +CC(C)NC(=O)CNC(=O)c1cccc2nscc12 +CCC1CN(Cc2c(C)nn(CCC(=O)OC)c2C)CC(C)O1 +CCOc1cccc(NC(=O)c2cccc(OC)c2O)c1 +CNC(=O)NC(C)(C)C(=O)N(C)Cc1ccccc1 +CCNc1c(F)cccc1C(=O)N(CC)CC(C)C +CN(Cc1cccnc1)C(=O)c1cc2ccccc2cc1OC(F)F +Cc1cc(OC(=O)COCC2CC2)ccc1Cl +Cc1cc(C)n(CC(C)NC(=O)Nc2ncn(C)n2)n1 +Cn1ncc2c(N3CCCC3)nc(C(=O)NCc3cccs3)nc21 +CCC(C(=O)N1CCC(O)(c2ccccn2)CC1)c1ccccc1 +CN(C(=O)c1ccsc1)c1nc2ccccc2s1 +CN(CCOCC1CC1)C(=O)NC1CC1c1ccccc1F +COC(=O)CNc1ccc(C#N)c(C(F)(F)F)c1 +Cc1cc(N)nc(SCC(=O)c2ccc3c(c2)CCC(=O)N3)n1 +CNc1nnc(SCc2cc(=O)n3c(C)cccc3n2)s1 +CC(C)c1ccc(C(C)NC(=O)c2ccc(=O)n(C)n2)cc1 +CCn1nc(C)c(CN(C)Cc2ccc(C(=O)OC)cc2)c1C +Cc1cccc(C(=O)N2CCc3ccccc32)c1N +O=C1CCC2(CCOC2)CN1CCC1=CCCCC1 +COc1cc(CN2CCCC(c3nncn3C)C2)cc(OC)c1 +COc1cc(CNC(=O)c2cc(C(C)(C)C)nn2C)ccn1 +CCCNC(=O)CNS(=O)(=O)c1ccc(C)c(N)c1 +Clc1ccc2c(c1Cl)CCNC2Cc1cccnc1 +CC(=O)N1CCCN(c2nc3c(s2)c(C)nn3C)CC1 +CN(Cc1ccccn1)C(=O)c1cc2c(s1)CCCC2 +COc1c(C)cnc(CNC(=O)NCCc2ccccc2)c1C +Cc1cccc(C(C(=O)N2CCCn3nc(C#N)cc3C2)N(C)C)c1 +O=C(NCc1ccco1)c1ccccc1NCCCO +CCC1CCCCN1C(=O)Nc1cccc(C(C)=O)c1 +N#Cc1cccc(C(=O)N2CCC(Oc3ccc(Cl)cn3)CC2)c1 +CC(Oc1ccc(Br)cc1Br)C(N)=O +COC(=O)C(C)Sc1nc(=O)ccn1C(C)C +CC(C)COc1ncc(CNC(=O)NCCO)cc1Cl +Cc1nnc(COc2ccc(NC(=O)C3(C#N)CCCC3)cc2)o1 +O=C1CN(C(=O)c2ccc(NC(=O)c3ccco3)cc2)CCN1 +O=S(=O)(Nc1ccnn1CC1CC1)c1cccc2nonc12 +CC1CCCC(N(C)C(=O)c2cccc3[nH]ccc23)C1 +CN(C(=O)NC1CCC2(CC1)OCCO2)C1CCCCC1 +CC(C)c1nc(CC(=O)Nc2cccc3cn[nH]c23)cs1 +O=C(NCc1ccccn1)c1cccn1Cc1cccs1 +N#CCCN(CCN1CCOCC1)S(=O)(=O)c1ccccc1F +O=C(Nc1nc(C2CC2)cs1)C1CCOCC1 +COc1ccc(CCc2nn3cc(N)nc3s2)cc1 +Cc1cc(C(=O)NCc2ncc(C(C)(C)C)o2)nn1-c1ccccc1 +O=C(CSc1ccccn1)NCc1ccccc1 +Cc1cc(C(=O)OCCc2scnc2C)ccc1-n1cncn1 +O=c1cc(CN2CCOCC2)n(CCN2CCOCC2)cc1O +N#CC1(NC(=O)c2cccc3c2OCO3)CCCCC1 +COc1ccccc1NC(=O)C1C(=O)OC(C)(C)OC1=O +COCc1cc(C(=O)NCc2ccc(C)s2)ccc1F +C=C(C)Cn1nnc(C#N)c1-c1cccc(Cl)c1 +CCOC(C)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +Cc1coc(-c2ccc(C)c(NC(=O)Cc3ccc[nH]3)c2)n1 +O=C(c1ccncc1)N(Cc1ccco1)Cc1cccs1 +Cc1nc(CNc2ccc(C(=O)NCC(C)C)cc2C)cs1 +CN(Cc1ccccn1)C(=O)c1ccc2c(c1)CCCC2 +Cc1nc2ccccc2n1CCNC(=O)c1cc(C2CC2)[nH]n1 +Cc1c(C(=O)NCCC(=O)Nc2ccccc2)cn2nc[nH]c(=O)c12 +COCC(=O)Nc1nc(C)c(Cc2ccc(F)cc2)s1 +CCn1cc(S(=O)(=O)Oc2cccc(-n3cncn3)c2)cn1 +CCc1n[nH]c(C2CN(C(=O)Cc3ccc4c(c3)CCC4)CCO2)n1 +O=C(NCCSc1ncn[nH]1)c1cccc(-n2cccn2)c1 +CC(=O)Nc1ccc(NC(=O)c2cccc(OCC(C)C)c2)cc1 +COc1c(F)cc(NC(=O)NCC2CCC2)cc1F +COc1cc(CO)ccc1OCc1cccc(Br)c1 +COc1ccc(Cl)cc1C(O)CCC(=O)NCC(C)C +CC(C)(C)OC(=O)CN1CCCC(C(=O)NCC2CC2)C1 +COC1CC2(CCN(C(=O)C(C)C)CC2)c2cc(F)ccc21 +COc1ccc(CN(C(=O)c2ccc(OC)c(F)c2)C2CC2)cc1 +NC(=O)C1Cc2ccccc2CN1Cc1cc(-c2ccco2)on1 +Cc1cccc(-c2ncccc2CNC(=O)C2CCC2)c1 +COC(=O)c1ccc(Cl)cc1NCc1cnc(C)s1 +Cc1c(CC(=O)N2CCOCC2)c2c(n1C(C)C)CC(C)(C)CC2=O +CCCC(=O)N1CCCC1C(=O)Oc1cccc(F)c1 +CC(O)CC(C)CNC(=O)Nc1cnc(C(C)(C)C)nc1 +Cc1cc(C)c(C)c(OC(=O)C2CCN(c3cnccn3)CC2)c1 +CNC(=O)c1ccc(CS(=O)(=O)c2ccc(C(C)C)cc2)cc1 +CN(C)C(=O)N1CCOCC2(CCC(Cn3ncccc3=O)O2)C1 +Cc1nc(C2CC3CN(C(=O)Cc4ccccn4)CC3O2)no1 +CNS(=O)(=O)c1cc(NC(=O)c2ccc(F)cc2F)ccc1C +CCOC(=O)CNC(=O)c1ccccc1SCC +COC(=O)c1ccc2c(c1)CCN2C(=O)C1CC2C=CC1C2 +Cn1cccc1C1COCCN1C(=O)c1ccccn1 +Cc1ccc(NC(=O)Cn2nnn(-c3ccccc3)c2=O)c(F)c1 +c1ccc(-c2cc(CN3CCOCC34CCC4)n[nH]2)cc1 +Cn1cc(NC(=O)c2cccc(OCc3cn4ccccc4n3)c2)cn1 +Cn1c(SCC(=O)c2ccc(F)cc2F)nc2ccccc2c1=O +CC(=O)Nc1ccc(C(=O)Nc2c(C)n[nH]c2C)s1 +CNC(=O)c1ccc(NC(=O)NCCCC2CCCC2)cc1 +O=C(NCc1ccccc1-n1cncn1)c1cc2sccc2[nH]1 +CCNc1nc(C(N)=O)c(NC(=O)c2cccc(Cl)c2)s1 +CC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2cccc(F)c2)c1C +CCOc1ccc(CC(=O)Nc2ccc(N)cn2)cc1 +Cc1ccccc1C1CC(=O)Nc2c1cnn2-c1ccc(F)cc1 +O=C(CCN1C(=O)COc2ccccc21)Nc1cccc(Cl)c1 +C=CCn1c(C)nnc1SCC(=O)Nc1ccc(F)cc1Cl +CCc1noc(CC)c1CC(=O)Nc1sccc1C(=O)NC1CC1 +Cc1ccc(N(C)c2c(-c3ccc4c(c3)OCC(=O)N4)c(=O)c2=O)cc1 +COc1ccc(-n2ccc(=O)c(C(=O)Nc3ccc(C)cc3)n2)cc1 +CC(O)c1cccc(S(=O)(=O)N2CCNC(=O)C2)c1 +O=C(COc1ccc(F)cc1F)N1CCc2ccccc21 +CCc1cccc2c(-c3cn4cc(S(N)(=O)=O)ccc4n3)c[nH]c12 +COCC(C)NC(=O)Cn1cnc2sccc2c1=O +CC(C)CN1CCN(Cc2cc(C3CCCCC3)no2)C(C)C1=O +COC(=O)c1ccc(Nc2ncnc(N3CCCCC3C)c2N)cc1 +N#Cc1ccc(-c2ccncc2)n2nc(C(F)(F)F)nc12 +COC(C)(C)c1noc(C2CCCN(C(=O)c3ccccc3)C2)n1 +CCNC(=O)CNC(=O)CNC(=O)c1cc(C)nn1C +COC(=O)c1cc2c(Br)cc(OC)c(OC)c2[nH]1 +COc1ccc2nc(C)c(C(=O)Nc3c(C)cc(C)nc3C)cc2c1 +CS(=O)(=O)c1ccc(C(=O)NCc2ccco2)cc1 +O=C(NCC1(c2ccc3c(c2)OCO3)CCCCC1)c1n[nH]c(=O)[nH]1 +O=C(Nc1ccccc1F)C1CC(=O)N(C2CCCCC2)C1 +CC(C)N(C)S(=O)(=O)c1ccc(F)c(C(=O)N(C)C)c1 +O=C(Cn1cnc(-c2ccc(F)cc2)cc1=O)Nc1ccncc1 +COc1cc(Cl)c(OC)c2c1C(C)(C)CNC2 +COc1ccccc1OCC(=O)NCC(C)(O)c1ccsc1 +Fc1cccc(CN(CC2CCCO2)c2ccc3nnnn3n2)c1 +CC(C)(O)C1CCCN1C(=O)NCc1ccccc1OC1CCC1 +COC(=O)c1ccccc1NC(=O)C1CN(C(=O)c2cccs2)C1 +CCOc1ccc(NC(=O)c2cncc(N)c2)cc1 +N#Cc1cnc(-c2ccc(Cl)c(Cl)c2)nc1N +O=C(NCc1cccnc1)C1(c2ccc(F)cc2F)CCOCC1 +COc1cccc(C(=O)NC2CCN(c3ccc(C)cc3)C2=O)c1F +COc1ccc(F)cc1NC(=O)NCCCNC(=O)C(C)C +COc1ccc(F)cc1-c1cc(C(=O)OC(C)C)n(C)n1 +CC(C)N(C)C(=O)c1cccc(S(=O)(=O)N2CCCCC2)c1 +CCNC(=O)C1CCCN(S(=O)(=O)c2ccc(Cl)cc2F)C1 +Cc1nnc(Oc2ccc(S(C)(=O)=O)cc2)c(C#N)c1C +NC(=O)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 +NC(=O)c1cc(-c2cccs2)n(-c2ccccc2)n1 +COC(=O)c1sc2nc(-c3ccsc3)ccc2c1N +COCCCNC(=O)CSc1ccccc1O +CCS(=O)(=O)N1CCC(C(=O)NCc2cccc(Cl)c2)CC1 +COc1cc(N2CCC3(CCCC(CN4CCOCC4)O3)C2)ncn1 +CCCCCS(=O)(=O)N1CCN(Cc2cccn2C)CC1 +O=C(NCc1cccc(C(F)(F)F)c1)c1cn[nH]c1-c1ccccc1 +N#Cc1cnc2nc(Cc3ccccc3)nn2c1N +CN(CC1CC1)C(=O)c1cn(C)nc1-c1ccc(F)cc1F +CC(=O)c1cccc(NC(=O)c2ccc(Cn3cccn3)cc2)c1 +CN(CC(=O)N1CCCC1)C(=O)c1ccc(F)cc1 +CCOC(=O)CN(C(=O)C(C)NC(C)=O)C1CC1 +CCn1nc(C)c(CN2CCCC(c3cnccn3)C2)c1C +CC(C)n1nc(-c2ccccc2)cc1NC(=O)NCc1ccccn1 +O=C(Nc1ccc(Cl)cc1)c1ccc(N2CCCC2=O)cc1 +CCCC(C)N(C)C(=O)Nc1cnn(CC(N)=O)c1 +COc1ccc2oc(C(=O)N(C)C(C)C)c(C)c2c1 +NC(=O)CCCNC(=O)c1cc(=O)c2ccccc2[nH]1 +Cc1ccc2ncc(C(=O)Nc3c(C)cnn3-c3ccccc3)n2c1 +O=C(NCC1COCCO1)c1cc2ccccc2c2cccnc12 +CC1(C)CCc2cc(NS(C)(=O)=O)ccc2O1 +Cc1ccc(-n2cc(C(=O)OCCc3scnc3C)nn2)cc1 +CCOC(=O)CNC(=O)N1CCCC1c1ccccn1 +COc1ccc(F)cc1CN1CCN(C(=O)C2CC(=O)N(C)C2)CC1 +COCCN(CC(F)F)c1nc(C)nc2c1cnn2C +CCC(C)NC(=O)CN1CC(C(C)C)Oc2cccc(N)c21 +N#Cc1ccccc1Cn1c(NCCO)nc2ccccc21 +O=C(NCCN1CCOCC1)NCc1cccc(Cn2ccnc2)c1 +Cn1c(=O)[nH]c(=O)c2[nH]c(CCC(=O)NCC3(C)CCCC3)nc21 +O=C(CN(Cc1ccccc1)CC(O)c1cccs1)N1CCCC1 +COc1ccc(S(=O)(=O)N(Cc2ccccc2OC)C2CC2)cc1 +CCOC(=O)C(C)(NC(=O)c1cnn(-c2ccncc2)c1C)C(C)C +COC(=O)N(C)CC(=O)Nc1cccnc1Oc1cccc(C)c1C +CN(CC(=O)NC(C)(C)C)C(=O)c1ccc(Br)cc1O +CCc1cc(=O)n2nc(NC(CO)C(C)c3ccccc3)sc2n1 +CC(=O)Nc1c(C)cccc1C(=O)OCc1cccc(C#N)c1 +COc1ccc(F)cc1NC(=O)NCc1ccccc1-n1ccnc1 +CC(=O)Nc1nc(C(=O)OCc2ccoc2C)cs1 +CC1(C)OCC2(CO1)CN(C(=O)c1ccc(Cl)cc1)C2 +Brc1cnc(N2CC3CC=CCC3C2)nc1 +CC(C)C(=O)Nc1ccc(C(=O)NCCNC(=O)C2CC2)cc1 +Cc1c(C(=O)OCc2nc(N)nc(N)n2)oc2c(Cl)cccc12 +COc1ccc(C(N)=O)cc1NC(=O)CCC(=O)c1ccccc1 +CCn1cc(C(=O)Nc2cc(C)cc3cccnc23)cn1 +CCC1COC(C)CN1C(=O)c1cc(Cl)ccn1 +CCN1CC(C(=O)N2CCCc3ccccc32)CC1=O +CN(C)C(=O)N1CCn2nc(CNc3ncnc4[nH]cnc34)cc2C1 +CCN(CC)C(=O)C1=C(C)NC(=O)NC1c1c(F)cccc1Cl +Cc1nc(C(F)(F)F)ccc1C(=O)N1CCn2cccc2C1C +CC(Oc1ccccc1C#N)C(=O)N1CCCS1(=O)=O +CC(=O)NCCNC(=O)NC1CC(C)CCC1C(C)C +Cc1ccc(O)c(C(=O)Nc2ccccc2C#N)c1 +O=C(NCc1nc2ccccc2[nH]1)C1CC1(Cl)Cl +COC(=O)C1=C(C)Nc2nnnn2C1c1sccc1C +CCOc1c(CN2CCNC(=O)C2CC)c(C)nn1CC(C)C +CN(C(=O)Nc1cccnc1)C1Cc2ccccc2C1 +O=S(=O)(Cc1nc2ccccc2s1)c1ccccc1 +CC(C)NC(=O)Nc1ccc(F)c(NC(=O)OC(C)(C)C)c1 +Nc1cccc(CC(C(=O)N2CCCCC2)c2ccccc2)c1 +O=C(NCCNC(=O)c1ccco1)NCc1csc(C2CC2)n1 +N#Cc1ccc(C(N)c2nnc(C3CCCC3)o2)cc1 +Cc1noc(C)c1CC(=O)N1CCCC1Cn1cccn1 +COc1ccc(NC(=O)CSc2nnc(CC(C)O)n2C)cc1 +COc1ccc(-n2ccnc2-c2nc3c(cnn3CC(C)C)[nH]2)cc1 +Cc1nnc(C(C)Nc2ccc(CN3CCOC3=O)cc2)o1 +COc1ccc(OC)c(-c2nc(CC#N)cs2)c1 +C=CCN(Cc1ccccc1F)C(=O)NCCNC(C)=O +COc1ccccc1OCC(=O)Oc1ccc2ccc(=O)oc2c1 +COc1ccc(Cl)cc1N(C)C(=O)c1cccc(C(=O)N(C)C)c1 +Cc1nc(CCCC(=O)Nc2cccc(-c3cn[nH]c3)c2)cs1 +CCOC(=O)CNC(=O)N1CCCC(C(=O)c2sccc2C)C1 +Cc1cc(C(=O)Nc2ncc(Cc3ccc(C#N)cc3)s2)nn1C +Cc1csc(NC(=O)Cc2coc3c(C)c(C)ccc23)n1 +O=C(c1ccc(F)cc1F)N(Cc1ccncc1)Cc1cccnc1 +COCc1cc(C(=O)N2CCOCC2C2CC2)no1 +CC(C)COc1ncnc(NCc2ccccc2)c1N +CCCc1nnc2n1NC(c1cc3ccccc3n3nnnc13)S2 +COC(=O)C(NC(=O)c1ccccc1OC)C(C)C +CC(=O)Nc1cccc(C(=O)N(CCC#N)Cc2cccnc2)c1 +Cc1noc(C)c1C(C)C(=O)NCC1(c2ccc(F)cc2)CC1 +Cc1ccc2c(c1)c(=O)c(C(=O)Nc1ccccc1)nn2C +O=C(NC1(c2ccc(Cl)cc2)CCC1)C1COCCO1 +Cc1cc2c(SC(C)C(=O)N(C)C(C)C)ncnc2s1 +CCC(NC(=O)C1(c2ccc(F)cc2)CC1)c1ccc(OC)cc1 +O=c1[nH]ncc(-c2ccc3c(c2)OCCO3)c1CO +Cc1cc(NC(=O)NC(C(N)=O)C(C)(C)C)ccc1C(=O)NC(C)C +Cc1cccc(CN(C(=O)c2nn(C)cc2Cl)C(C)C)c1 +COc1ccc(N2CC(C)Cn3c2nc2c3c(=O)[nH]c(=O)n2C)cc1 +COc1cccc(CS(=O)(=O)c2ccc(N)cc2)c1 +COc1ccc(C)cc1NC(=O)N1CCCC1c1cc(C)on1 +COCCNC(=O)Cn1nnc(-c2ccccc2)n1 +CCCCSc1nc(N)cc(N2CCC(CNC(C)=O)CC2)n1 +CN(C(=O)c1ccc(-c2ncon2)cc1)C(CO)C(C)(C)C +Cn1ccc(C(=O)Nc2nc(-c3cccs3)cs2)n1 +CCCn1ncc2cc(C(=O)N3CCN(C)CC3)c(N)nc21 +CCCC(CC(=O)OC)c1cc(C)ccc1OC +CS(=O)(=O)NCCc1ccc(Cl)c(Cl)c1 +CC(=O)N1CCc2cc(NC(C)C(=O)Nc3ccc(C)cc3)ccc21 +COc1cccc(N2Cc3nc(N4CCC(O)CC4)ncc3C2=O)c1 +CC(Oc1cccc(OCc2ccccn2)c1)C(N)=O +COCCCC(=O)N1CCN(Cc2cnn(-c3ccccc3)c2)CC1 +O=C(NCc1ccc(-c2csnn2)cc1)C1CC1 +C#CCN(C(=O)Nc1ncc(C)s1)C1CCCCC1 +O=C(c1cn[nH]n1)N1CCCC1c1ccc2c(c1)OCCO2 +O=C(COc1ccccn1)NCc1ccccc1Cl +Cc1ccc(C(=O)NCCCOCC2CC2)c(O)c1C +COc1cc(-c2noc(-c3cncc(Br)c3)n2)ccn1 +CCCS(=O)(=O)NC1CCN(C(=O)c2ccsc2)CC1 +Cc1cccc(C2CCCN2Cc2cnc(C(C)C)s2)n1 +Cc1ccc(-c2ccc(CCC(=O)NCC3CCCO3)o2)cc1 +CC1=NC2C(c3nc(-c4ncccn4)no3)=CC=CC2=C1C +Cc1ccc(S(=O)(=O)N2CCCC2c2nc(C3CC3)no2)cc1C +CCNC(=O)CN(CC)C(=O)C1(c2cccc(C(F)(F)F)c2)CC1 +CNC(=O)C1CN(C(=O)c2nccc3ccccc23)CC12CCCC2 +CCOc1cc(F)ccc1NC(=O)N1CCOC(C)(C)C1 +CC(Sc1nnc(C2CC2)o1)C(=O)Nc1ccc2c(c1)CCC2 +CC1CN(C2CCN(CC(O)c3c(F)cccc3F)CC2)CCO1 +COc1cc(S(=O)(=O)NCCCO)ccc1Br +Cc1cc(C)c(NS(=O)(=O)c2ccc(C(N)=O)cc2)c(C)c1 +OC(CN1CCOC(c2nccs2)C1)c1ccc(F)cc1 +Nc1cccc2c1CCN(S(=O)(=O)c1ccccc1)C2 +Cc1cc(-c2cc(=O)n(CC(=O)NCC3CC3)nc2C(C)C)on1 +Cc1ccccc1COc1cccc(NC(=O)c2cnn(C)c2)c1 +NC(=O)c1ccc(OCC2OCCO2)cc1Cl +NC(=O)c1ccccc1NC(=O)CNc1ccc(Cl)cc1 +Cc1cccc(C(=O)NCCc2ccccn2)c1N +CC1CCCCN1C(=O)CSc1nnc(N)n1C1CC1 +CCSc1nnc(SCc2cn3c(C)cccc3n2)s1 +COc1ccc(-c2c(C)nc3nc(SC)nn3c2N)cc1OC +CCSc1nnc(CNC(=O)OC(C)(C)C)n1-c1ccccc1 +COc1ccc(CCC(C)NS(=O)(=O)C(C)C)cc1 +CC(C)NC(=O)CCNC(=O)NC1CCCCNC1=O +Cc1noc(C)c1CCC(=O)NCCC1=CCCCC1 +O=S(=O)(Oc1ccc(-n2cccn2)cc1)c1cccnc1 +CNC(=O)Cc1ccc(NC(=O)Cc2ccc(F)cc2)cc1 +CCCNC(=O)CN1CCN(c2ncnc3c2cnn3C)CC1 +CCCC(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +COC(=O)c1cccc(-c2nccn2CCc2cccc(F)c2)n1 +CC(CNC(=O)c1cncc(Br)c1)CN1CCOCC1 +COC1CCC(OC(=O)c2ccc(CCNC(N)=O)cc2)CC1 +COCCNC(=O)C(C)N1C(=O)COc2ccc(C)cc21 +CC(=O)Oc1cc(OC(C)=O)c(C(C)(C)C)cc1OC(C)=O +O=C(Nc1nnc(-c2cccs2)o1)c1cccc(F)c1 +O=C(c1ccc(-n2ccnc2)nc1)N1CCC(Cc2ccccc2)CC1 +NC(=O)c1ccccc1NC(=O)c1ccc(N2CCCC2)nc1 +CC1CN(CC(O)COc2cccc3ccccc23)C(C)CO1 +COCc1cccc(CNS(=O)(=O)c2sc(=O)[nH]c2C)c1 +Nc1nc2[nH]c(SCC(=O)Nc3ccccc3F)nc2c(=O)[nH]1 +NC(=O)c1ccccc1NC(=O)CSc1nc2ccccc2o1 +O=C(c1n[nH]c2c1CCC2)N(Cc1ccccc1)CC1CCCO1 +Brc1ccc(NCc2cccc3c2OCO3)nc1 +CC(C)=CCCC1(C)CCC(=O)N(CCc2cc(=O)[nH]c(C)n2)C1 +Cc1nnc(SCC(=O)NCC(F)(F)F)s1 +CCS(=O)(=O)c1ccc(O)c(NC(=O)c2cc(C(C)=O)c[nH]2)c1 +COc1ccnc(NCc2ccc3c(c2)OCCO3)n1 +CNS(=O)(=O)c1cccc(NC(=O)c2ccoc2C)c1 +Cc1noc(C)c1CC(C)NC(=O)Cc1cccc(OCC#N)c1 +COc1ccc(NC(=O)c2cccc(-c3nnnn3C)c2)cc1 +O=C(Nc1cnccc1CO)c1ccc2[nH]ccc2c1 +CC1CCCCN1C(=O)Cc1ccccc1-c1nn2cnnc2s1 +COCCNC(=O)Nc1cc(Cl)ccc1Cl +N#CCc1ccc(NC(=O)NCCCNc2ccccc2)cc1 +CCCc1nnc2sc(Cc3ccc(OC)cc3)nn12 +CC1CN(Cc2nc3ccccc3s2)CC(C)O1 +C=C(C)CN(CC)C(=O)COc1ccc(-n2cnnn2)cc1 +CCOC(=O)CN(C(=O)c1ccc(F)c(F)c1)C1CC1 +O=C(COc1ccc(F)c(F)c1)NCC(F)(F)F +CC1(C(=O)NCCc2ccccc2)Oc2ccc(Cl)cc2NC1=O +Cc1noc(C)c1CC(=O)Nc1cnn(C2CCOC2)c1 +O=C(NCc1cn[nH]c1)c1ccc(O)c(Cl)c1 +CCn1cc(C(=O)N2CCC(NC(=O)c3ccccc3)CC2)cn1 +O=C(NCC1CCCCC1)c1c[nH]c(-c2n[nH]c3ncccc23)c1 +CC(=O)NCC1NCCc2cc3c(cc21)OCCO3 +CSc1nnc(SCC2CCOCO2)s1 +COc1cccc(C(O)C(C)NCc2ccc(F)cc2)c1 +CC(C)(C)c1ccc(C(=O)NCC(=O)OCC(N)=O)cc1 +CCCNC(=O)C(C)NC(=O)c1cc(Cl)ccn1 +C#CCN(Cc1ccc(F)cc1)Cc1cnc(N2CCOCC2)nc1 +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)N1CCc2ccccc2C1 +CCCCn1nc2c(c(CO)c1=O)CC(C)CC2 +CCOC(=O)c1c2ccc(OCC(N)=O)cc2n2ccccc12 +CN(C)S(=O)(=O)NCCCn1ccc2ccccc21 +CN(C)C(=O)C1CCCN(C(=O)Nc2cccs2)C1 +Cc1cc(CN(C)S(=O)(=O)c2cccc(C(F)(F)F)c2)no1 +CC(C)(C)C(=O)N1CCC(C(=O)Nc2ccc(F)c(F)c2)CC1 +COc1nc(OC)nc(Sc2ccc(N)cc2)n1 +COCc1cccc(Nc2ncnc3c2cnn3CCO)c1 +C#CCOc1ccc(CCNC(=O)NCc2ncn(C)n2)cc1 +CC(C)(C)c1nnc(N2CCC3(CC2)OCCCC3O)o1 +Cc1ccc(C2c3cccn3CCCN2Cc2ccncc2)cc1 +COc1ccc(Cl)cc1-c1n[nH]c(SC)n1 +C#CCN1CCN(S(=O)(=O)c2cc(OC)c(OC)cc2F)CC1 +O=C(c1cccc(N2CCNC2=O)c1)N1CCOC(C(F)(F)F)C1 +CC(c1ccccc1F)N(C(=O)CCn1cccn1)C1CC1 +Cn1c(C2CCCCN2C(=O)c2ccc(F)cc2)nc2ccccc21 +O=C(Cn1nc(N2CCOCC2)ccc1=O)NCc1ccc(F)cc1 +CC(=O)c1ccc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)cc1 +N#Cc1nc2ccc(F)cc2n1Cc1ccc(N)nc1 +CC(=O)Nc1cc(-c2nnc3n2CCCCC3)ccc1F +O=C(CCn1nnc2ccccc2c1=O)NC1CCCC1 +COc1cc(NC(=O)C2(c3ccccc3)CCC2)cc(OC)c1 +CC(C)COC(=O)N1CCN(C(=O)c2ccccc2)CC1 +CCc1cc(C(=O)NC(C(=O)NC)c2ccc(F)c(F)c2)[nH]n1 +Cn1nccc1CNC(=O)NCCc1ccc(F)cc1 +CN(Cc1ccncc1)C(=O)Cc1ccc(F)c(F)c1 +CNc1snc(C)c1C(=O)NCc1cccnc1-n1cccn1 +CCCCc1nc(CN2CCN(c3cccc(F)c3C#N)CC2)no1 +Cn1c(C(=O)n2ncc(C#N)c2N)cc2ccccc21 +NC(=O)CSc1nc2ccccc2n1CC(=O)N1CCOCC1 +Cc1cnc2c(c1)N(S(=O)(=O)c1ccc(C#N)cc1F)CCO2 +CC(C)(C)NC(=O)COC(=O)c1c(Cl)cccc1Cl +CN(C(=O)Cn1ccc(=O)n(C)c1=O)c1cccc2ncccc12 +Cc1ccc(-c2noc(CS(=O)(=O)c3ccccc3)n2)cc1 +CCOC(=O)c1ccc(NC(=O)CCc2ccccc2N)cc1 +COCCC1(CNC(=O)Nc2ccc(C(C)=O)c(C)c2)CCCC1 +N#CC1(C(=O)NC2CCN(c3ccc(Cl)c(F)c3)C2=O)CCCC1 +CCCCC(=O)N1CCc2nc(NC(=O)c3ccco3)sc2C1 +CCN(CC)C(=O)Cn1[nH]c(=O)c2ccccc2c1=O +COC(=O)C1(N(C)C(=O)Cc2cccs2)CCCCC1 +N#Cc1ccc(N(CCO)CCc2ccccc2)nc1 +Cc1cc(C)cc(Nc2ncnc(NC(C)C)c2N)c1 +CCOc1ccc(CC(=O)N2CCCC2c2cc(C)on2)cc1 +CCn1nc(C(=O)NC(C(=O)OC)C(C)C)c(=O)c2cc(F)ccc21 +O=C(CCC1CCCC1)N1CCC(c2nnc(-c3ccco3)o2)CC1 +CC(NC(=O)CSc1nc(N)c2ccsc2n1)c1ccccc1 +CCN(CC)C(=O)CNc1ccc(C(=O)N(C)C)c(C)c1 +CCOC(=O)Cc1cnnn1Cc1ccccc1C#N +COc1cc(-c2nccs2)cc(N)c1OC(C)C +CC(C)c1noc(OCc2ccccc2Oc2cccnc2)n1 +Cc1ccc(C2CCCN2S(=O)(=O)c2cnn(C)c2)o1 +O=C(NC1CCOCC1)c1ccc(C2CCCO2)s1 +Cc1ccc(C)c(S(=O)(=O)Oc2cc(C(=O)N(C)C)ccc2C)c1 +Cc1ccc(S(=O)(=O)n2nc(-c3cccc(F)c3)cc2N)cc1 +COc1ccc(CC(=O)N2CCC(c3cccs3)CC2)cc1OC +CCCn1c(=O)n(CC)c(=O)c2c1nc(NC)n2CC +CC(C(=O)c1ccc2c(c1)NCCO2)N1CCOCC1 +NC(=O)C1CCN(C(=O)c2cnn(-c3ccccc3)n2)c2ccccc21 +CN1C(=O)c2cc(Cl)ccc2NC1c1c[nH]nc1-c1cccnc1 +Cc1ccc(OCCNC(=O)c2ccccc2N)cc1C +CCC(C#N)Oc1cccc(CNC(=O)c2cc(C)on2)c1 +CN(C(=O)Cc1cccc(F)c1F)c1ccccc1 +O=C(Cc1ccc(OC(F)F)cc1)NCCC(=O)N1CCCC1 +CC(C)(C)NS(=O)(=O)c1ccc(C(N)=O)cc1 +Nc1cc(Cl)cc(Cl)c1NC(=O)COCCO +COCCCNC(=O)Nc1c[nH]c2ccccc2c1=O +CC1CC1c1ccc(CN2CCC3(C2)OCCO3)o1 +CCNC(=O)NC1(C(=O)N2CCOC(C)C2)CCCC1 +CC(=O)Nc1ccc(C)cc1NC(=O)c1cccc2c1ccn2C +Cc1nc(N2CCN(C(=O)c3ccccc3)CC2)cc(-n2cccn2)n1 +O=C(Nc1ccc(Cl)c(Cl)c1)c1cc(-c2ccncc2)on1 +O=C(CSc1nccn1-c1cccc(F)c1)Nc1nccs1 +CC(NS(C)(=O)=O)C(=O)NCCc1c(F)cccc1F +CCc1cccc(NC(=O)CCc2ccccn2)c1 +COc1cccc(-c2noc(-c3cn[nH]c3C(C)C)n2)c1 +N#Cc1ccc(NCCCn2nc3n(c2=O)CCCC3)nc1 +CCC(O)c1cc2c(c(C)c1C)OCCC2NC(=O)C1CC1 +COc1coc(C(=O)Nc2ccccc2Cl)cc1=O +COc1ccc(N)cc1COc1cccc(F)c1F +CNc1nc(-c2sc(CC(C)C)nc2C2CC2)cs1 +CCCCN(Cc1ccccc1)C(=O)c1cc(OC)no1 +COc1ccc(CNC(=O)Nc2ccc(F)c(C#N)c2)c(OC)c1 +COCCCNC(=O)c1cc2c(OC)cccc2n1C +CC1CN(C(=O)c2ccc3c(c2)CCN3)CCCO1 +CC(=O)N1CCN(C(=O)C2CSc3ccccc32)CC1 +O=C(NCc1ccnc(-n2cccn2)c1)C1CCCO1 +CSc1ccc(NC(=O)CNC(=O)C2CCCC2)cc1 +CS(=O)c1ccc(C(=O)NCCc2nc3ccccc3s2)cc1 +CNC(=O)C(C)NC(=O)C(C)Oc1ccc(Cl)cc1 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)N1CCOCC1 +Cn1c(=O)c(-c2ccc(C(=O)N3CCOCC3)cc2)nc2ccccc21 +Cc1ccc(S(=O)(=O)NCCNC(=O)c2ccoc2)cc1C +COc1cccc(C(=O)N2CCN(Cc3nc(C)no3)CC2)c1 +Cn1cccc1CN(C1CC1)S(=O)(=O)c1cccc2ccccc12 +Cc1ccc(-c2csc3nc(SCC(N)=O)n(N)c(=O)c23)cc1 +CCC(CC(=O)NCC(=O)Nc1cccnc1)c1ccccc1 +COc1ccc(CCNC(=O)NC2CCSc3ccccc32)cc1 +CC(C)c1cc(C(=O)N2CC(c3ccccn3)C2)n(C)n1 +CCOc1ccccc1NC(=O)c1nc2nc(C)cc(C(F)F)n2n1 +CCOC1CCC2C1OCCN2CC1CCOCC1 +Cc1nn(CC(C)C)c2sc(C(=O)NCC(=O)N3CCCC3)cc12 +CCC(=O)N1CCN(C(=O)c2ccc(O)cc2)CC1 +CC1CCN(C(=O)c2cnc(-c3ccccc3)nc2)C(C)C1 +Cc1cc(C)n2c(CNCc3cccnc3OC(C)C)cnc2n1 +C=CCN(CC=C)C(=O)c1cn(C(C)C)c2cccc(N)c2c1=O +COc1cccc(OCC(=O)N2CCNCC2)c1 +CCNC(=O)c1cc(-c2ccc(OC)cc2)nc(N)n1 +CCC1CCCCN1C(=O)C(C)n1ncc(Br)c1C +COc1ccccc1Oc1ccc(NC(=O)c2cc(C)on2)cc1 +Cc1cc(NC(=O)C(C)NC(c2ccccc2)c2ccccc2)no1 +O=C1Cc2cc(NC(=O)c3cccc(Cl)c3Cl)ccc2N1 +N#Cc1cc2ccccc2nc1N1CCC(=O)CC1 +O=C(NCCc1csc(-c2ccncc2)n1)c1ccccc1 +Cc1cc(NC(=O)C2(c3ccc(F)cc3)CCC2)n(C)n1 +COC(=O)c1cnc(Nc2cccc(C)c2)nc1C +CCCc1cc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)no1 +O=C(c1ccc(-c2ccco2)[nH]c1=O)N(Cc1cccs1)C1CC1 +Nn1c(SCc2noc(C3CC3)n2)nnc1-c1ccc(F)cc1 +N#CCCCOc1cccc(NC(=O)C2CC3C=CC2C3)c1 +CC(NC(=O)CCc1ccccc1F)C(=O)N1CCCCC1 +Cc1ccc(C(CNC(=O)c2ccccc2F)N2CCOCC2)o1 +COc1cc(C)cc(C)c1S(=O)(=O)N1CCOCC1 +CC(NC(=O)c1ccc(O)cc1F)c1ccccc1 +CNC(=O)NCC(=O)Nc1c(F)cccc1NC1CC1 +CCCC1CCCN(C(=O)Nc2cnccc2C)C1 +CC(C(=O)NC1CC1)N1CCN(S(=O)(=O)c2cccs2)CC1 +COc1ccc(C)cc1NC(=O)C1CC2CCC1C2 +Cc1cc(O)c2c(c1)C(C(O)c1ccccc1)NCC2 +COC(=O)C1CN(Cc2cc(Cl)ccc2Br)CCO1 +Cc1nonc1CC(=O)NC(Cn1c(=O)oc2ccccc21)C(C)C +O=C(OCc1nccs1)c1ccc(-n2ccnc2)cc1 +O=C(NCC1CCOC1)c1cc(Br)ccc1Cl +CCCOc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1 +Cc1cc(C(=O)Cn2cnc(C#N)n2)c(C)n1CCC1=CCCCC1 +CC(C)CCNC(=O)N1CCCC1c1ccco1 +CCn1nc(C)cc1C(=O)NCC(=O)N(C)Cc1ccccc1F +Cc1nn(Cc2cccc(C#N)c2)c(C)c1Br +Cc1ccccc1C(C(=O)N1CC(c2ccccn2)C1)N(C)C +Nc1cccc(CCC(=O)Nc2ccc(C(=O)N3CCCC3)cc2)c1 +O=S1(=O)N=C(N2CCCc3ccccc32)c2ccccc21 +Cc1noc2nc(C(C)C)cc(C(=O)Nc3nccs3)c12 +COCC(=O)N1CCN(c2cc(C(F)(F)F)nc3ncnn23)CC1 +CCCN(CCC)C(=O)CN1C(=O)C(C)Nc2ccccc21 +CN(C)S(=O)(=O)c1cc(C(=O)N2CCCCCC2)ccc1F +Cc1cc(N)nc(SC(C)c2nc(C(C)C)no2)n1 +CC(C(=O)N(C(C)C)C1CCOCC1)c1cccs1 +Cc1ccc(C(C)NS(=O)(=O)c2cccc(-c3nnnn3C)c2)o1 +COc1ccc(NC(=O)c2cnn(-c3ccccc3C)c2C)cc1 +Cc1c(O)cccc1C(=O)N1CCN(Cc2ccc(Cl)cc2)CC1 +CCOc1ccccc1C(=O)Nc1ccc(N)cc1OC +COc1ccc(NC(=O)N2CCc3cc(OC)c(OC)cc3C2)cc1 +Cc1ccccc1-c1cn[nH]c1C1CCCN(Cc2ccoc2)C1 +Cc1ccc(C(C)NC(=O)Nc2cnc3c(c2)c(C)nn3C)o1 +CC(=O)NCCCCCC(=O)Nc1cc(C#N)ccc1Cl +CC1CCCC(C#N)(NC(=O)C2COc3ccc(F)cc3C2)C1 +CCC1CCC(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)CC1 +O=C(Cn1nnc2ccccc2c1=O)NCCc1ccccc1 +CC1CC1C(=O)C(C#N)c1nc(-c2ccccc2)cs1 +CNC(=O)C1(C)CCCN(C(=O)c2ccc(OC)nc2)C1 +COc1ccc2c(c1)nc(C(N)c1ccccc1)n2C1CC1 +CN(CCCC(=O)c1cccnc1)C(=O)OC(C)(C)C +Cc1cc(C)n(Cc2nc(-c3c[nH]c4ccccc34)cs2)c(=O)n1 +O=C(Nc1ccc2c(c1)COC2)c1ccn(-c2ccccc2)n1 +CC(=O)N1CCCC(c2nccnc2Cc2ccc(C)cc2)C1 +CCOC(=O)c1ccc(CNC(=O)c2cnc(C)nc2C)o1 +Cc1ccc(CC(=O)Nc2ccc(C(=O)NC(C)C)cc2)cn1 +CC1CCCN(S(=O)(=O)NCc2ccccc2N2CCCC2)C1 +Cc1ccc(C(=O)NCCCn2ccnc2)c(O)c1 +Cc1c(C(=O)NC2CCCNC2=O)cnn1C(C)(C)C +CC(C)c1ccc(CN2CCN(C(=O)c3cnccn3)CC2)cc1 +COc1cccc(-c2cnnc(N(C)Cc3cn(C)nc3C)n2)c1 +CCOc1cc(-c2cc(C(=O)OC)[nH]n2)cc(N)c1OCC +CC(=O)c1cc(Cl)ccc1OCC(=O)NC(C)C +C#CCNC(=O)Cc1cc(Cl)c2c(c1)OCCCO2 +CC(C)N(C)c1cccc(NC(=O)Cc2cccc(OCC#N)c2)c1 +Cc1ccc(C2CN(C(=O)NCCc3nc(C(C)C)no3)CCO2)o1 +CC1CN(C(=O)Cn2ccc(=O)[nH]c2=O)c2ccccc21 +O=C(CSc1nnc(NC(=O)C2CC2)s1)NC1CCCCC1 +Cc1nc(C)c(C(=O)NC2CCc3c(F)cccc32)s1 +Cc1ccc(S(=O)(=O)Cc2ncc(C(C)C)o2)c(C)c1 +Cc1cccc2[nH]cc(CC(=O)NCCN3CCCCCC3=O)c12 +O=C(NCc1ccc(Cl)cc1)C1CC(=O)N(C2CCOCC2)C1 +CC1(COC(=O)C2CCCN(C(=O)c3ccc(F)cc3)C2)COC1 +COc1ccc2c(c1)OCC(CNC(=O)C1(C#N)CCOCC1)C2 +COc1ccsc1C(=O)Nc1cccn(Cc2ccccc2)c1=O +Cc1cccc(S(=O)CC2CCN(C(=O)OC(C)(C)C)C2)c1 +CC(=O)Nc1cc(C(=O)Nc2ccncc2)ccc1F +O=C(NCC#Cc1ccccc1F)c1cc(-c2ccco2)n[nH]1 +CC(Oc1ccccc1Br)C(=O)NCc1cc[nH]n1 +CCC1C(=O)NCCN1Cc1cc(C#N)n(C)c1C +Cc1cc2c(cc1C)NC(c1cccs1)=CC(=O)N2 +CCCOc1cc(CNC(=O)Nc2cccc(C(C)=O)c2)ccn1 +CCOc1ccc(-c2nc(-c3ccc(C)nc3OC)no2)cc1 +COc1ccc(NC(=O)c2ccc(C)c(C)c2)cc1S(N)(=O)=O +Cc1cnn(CCC(=O)NC(C)c2ccc(C#N)cc2)c1 +CC(C)NC(=O)c1snc(-c2ccncc2)c1N +CCOC(=O)c1ccc(NC(=O)CSc2nc(C)cc(C)n2)cc1 +CC(C)CCNC(=O)c1cc(=O)n(C)c2ccccc12 +CCCNC(=O)Cn1c(=O)c2ccc(C(F)(F)F)nc2n(C)c1=O +Nc1ncnc(Nc2ccc(Oc3ccccc3)cc2)c1N +COC(=O)C1CCc2c(ccc3c2CCCC3)C1=O +CCCCOC(=O)c1ccc(NC(=O)C2CCOCC2)cc1 +CCC(C)n1ncc(C(=O)NCCc2cscn2)c1C1CC1 +O=C(NCCc1ccncc1)c1n[nH]c2ccc(Cl)cc12 +CC(C)(C)OC(=O)NCC1CCN(C(=O)c2ccncc2)CC1 +O=C(CCCC1CCCC1)NCc1csc(=O)[nH]1 +Cc1ccc(Cn2nc(C(=O)N3CCCC3)ccc2=O)cc1 +CCc1ccc(N2CCC(C(=O)NCCCOC)C2=O)cc1 +Cc1c(CCC(=O)Nc2nn(C(C)C)cc2C#N)cnn1C +CCN(CC)S(=O)(=O)NC(C)c1c(C)nn(C)c1C +COc1ccc(CC2Oc3ccccc3N(CCO)C2=O)cc1N +CCc1nnc(SCC(=O)Nc2cccc(OC)c2)n1C +CSc1c(Cl)cccc1NC(=O)NCc1nncn1C1CC1 +Cc1nn(C)c(C)c1NC(=O)CN(CCC#N)Cc1ccco1 +NC(=O)c1ccc(C(=O)NC2CCCc3ccccc32)cc1 +Cc1cc2c(cc1S(=O)(=O)NC1CC1)NC(=O)CO2 +COc1ccc(-c2nc(C)c(CCO)s2)cc1OC +Cc1ccc(COc2cccc3ccc(=O)n(CC(N)=O)c23)cc1 +CCN1CCN(C(=O)C(C)Sc2ccccc2OC)CC1 +Cc1sc(=O)n(CC(=O)C(C#N)c2ccccn2)c1C +CCOc1ccc(NC(=O)Cc2c(C)noc2C)c(C)c1 +CC(OC(=O)CCc1ccc(C#N)cc1)c1ccc2c(c1)OCCO2 +Cc1cc(NC(=O)CCCc2cn(C)c3ccccc23)nn1C +CCc1nnc(NC(=O)Cc2cc(Cl)ccc2OC)s1 +CC(C)CNC(=O)c1nc(Cc2c[nH]c3ccccc23)no1 +CC(C)(C)C(=O)N1CCN(c2ccc(-c3ccncc3)nn2)CC1 +CC(C)(C)NC(=O)c1ccccc1C(=O)Nc1ccccc1 +CC(=O)c1ccccc1NC(=O)CCCn1nnc(-c2ccccc2)n1 +CC(=O)NCCC(=O)Nc1ccc(C(N)=O)cc1C +CC(C)(C)OC(=O)N1CCCN(C(=O)Cc2ccc(F)cc2)CC1 +C=CCNS(=O)(=O)c1ccc(C(=O)OC)cc1 +CCc1ccsc1C(=O)NC(C#N)c1cccc(OC)c1OC +Cc1ccc(C(=O)N2CCN(c3cc(Cl)ccc3C)CC2)c(=O)[nH]1 +CC(C)NC(=O)c1cccc(NC(=O)c2cc3ccncc3cn2)c1 +COCCCNC(=O)C(C)Nc1cc(Br)ccc1C +CNc1nc2ccccn2c1S(=O)(=O)N(C)C(C)C +Cc1nc(C)c(Oc2cccc(C(F)(F)F)c2)c(=O)[nH]1 +C#CCNC(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCCC1 +Cc1occc1-c1nc(NC2CCCC2)ncc1-c1ccncc1 +CC(=O)N1CCc2cc(NCc3ccc4c(c3)OCCO4)ccc21 +CCN1C(=O)C(c2ccccc2)Nc2cc(F)c(F)cc21 +Cc1ccc(CCC(=O)N2CCCC2CC(C)O)cc1 +CC(C)(C)n1cc(C#N)c(NC(=O)Cc2cccc(OCC#N)c2)n1 +CC(=O)c1ccc(C#CCNC(=O)NCc2ccc(F)cc2)cc1 +c1ccc(-c2nc(CNc3ccc(-n4cncn4)cc3)no2)cc1 +COc1cc(CNC(=O)c2cnc[nH]2)c2ccccc2n1 +CCCNC(=O)c1cccc(CNC(=O)N(C)Cc2ccccn2)c1 +Cc1cc(C2CCCN2C(=O)C(C)n2nc(C)cc2C)on1 +O=C(NCc1ncc[nH]1)C1CCC(=O)N(C2CCCCCC2)C1 +CCOCCNC(=O)Nc1ccc2c(c1)OCO2 +CC(C)(C)c1ccc2c(=O)n(CCCC#N)ccc2c1 +COc1cc(C2NCCc3c(N)cc(F)cc32)ccc1F +O=C(NCc1ccc2c(c1)OCCO2)NC1CCCCC1 +CCn1c(CNC(=O)c2cncn2-c2ccccc2)nc2ccccc21 +Cc1cccc2c1OC(C)(C)C(N1CCC(=O)CC1)C2O +Cc1nc(-c2ccccc2)sc1CSc1nnc(N)n1C +CC(C(=O)N(C)Cc1ccccc1N1CCCC1)n1ccnc1 +O=c1cc(CO)n(CCO)c(CN2CCOCC2)c1O +COC(=O)c1ccc(CN(C)Cc2cnccn2)s1 +COCCNC(=O)C1COC(=O)N1Cc1ccc(O)cc1 +COC(=O)CN1CCC(C(=O)OC)(c2ccccc2)CC1 +CCNS(=O)(=O)c1ccc2c(c1)C(C)(C)CN2C(C)=O +Fc1ccccc1-c1cn2nc(-c3ccco3)c(-c3ccco3)nc2n1 +O=C(NCc1cccc2c1OCCO2)C1COc2ccccc2C1 +O=C1COCc2[nH]c3ccc(Br)cc3c21 +CC(C)(CO)C1NCCc2c(OC(F)(F)F)cccc21 +Cn1cc(C#N)cc1C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +CC1CCCCC1NC(=O)c1cccc(C(N)=O)c1 +CCc1c(C)nn(-c2nc3ccccc3s2)c1N +Cn1cc(S(=O)(=O)NCc2ccc3c(c2)OCCO3)cn1 +Cc1nc(COc2ccccc2C(=O)N2CCC(C)CC2C)no1 +N#CCCN(Cc1ccco1)C(=O)c1ccc2cc[nH]c2c1 +O=C(CCNc1cccc(F)n1)Nc1ccc(Br)cc1 +COC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccccc1OC +COc1ccc(-c2cnc(NC(=O)NCc3ccccc3)n2C)cc1 +CSc1nnc2n(CCc3ccccc3)c(=O)c3sccc3n12 +Cc1nnc(C2Cc3ccccc3CN2Cc2ccc(C)c(C)c2)o1 +CCN(CC)C(=O)CSc1nc2cc(C)c(C)cc2[nH]1 +Cc1ccc(S(=O)(=O)Cc2ccc(C(=O)NC3CCCC3)o2)cc1 +O=S1(=O)NC(c2cccc(C(F)(F)F)c2)Nc2ccccc21 +Cc1ccc2ncc(C(=O)N(CC3CC3)c3cccnc3)n2c1 +COC(=O)CN(C(=O)CCc1cccc(Cl)c1)C(C)C +COC(=O)CCNC(=O)c1ccn(-c2ccc(OC)cc2)n1 +COc1c(Cl)cccc1NC(=O)CN1CCCCC1=O +CC(=O)NC(CC(=O)NC1CC1)c1ccc(Cl)cc1 +COc1ccc(CNc2nncc3ccccc23)cc1OC +CCOC(=O)CCn1c(-c2ccc(N)cc2)csc1=O +CCCCc1nc(C)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)s1 +CNC(=O)c1cccc(NC(=O)c2cc3ccc(F)cc3n2C)c1 +CC(C)N(C)S(=O)(=O)N1CCC(c2ccc(O)cc2)CC1 +Cc1cc(=O)n2c(n1)SCC2CC(=O)N1CCC(C)CC1 +CC12C(=O)c3ccccc3NC(=O)C1C2C(=O)NCC1CCCO1 +CC1=NCCN1S(=O)(=O)c1ccc(Cl)cc1 +Cc1nc(CN(CCC#N)Cc2ccco2)nc2ccccc12 +Cc1cc(C2NC(=O)c3n[nH]c(C)c3N2)ccc1F +OCCCSc1nnc(C2CC2)n1-c1ccccc1 +COCCOc1ccc(C(=O)N2CCC(O)CC2)cc1 +COc1cc(C(=O)Nc2cccc(F)c2)cc(OC)c1C +COc1cccc(CNc2cccc(NC(=O)c3ccoc3)c2)c1 +CC(NS(=O)(=O)Cc1cc(-c2ccccc2)no1)C(=O)N(C)C +Cc1cccc(-c2ccc(C(=O)NCCN3CCOCC3)c(=O)[nH]2)c1 +Cc1ccccc1C(=O)NCc1cc(-c2cccs2)on1 +CN(CC(=O)c1cccs1)C1CCN(C(=O)OC(C)(C)C)C1 +NC(=O)c1cn(-c2ccccc2)nc1-c1ccc(OC(F)F)cc1 +COc1ccc(OC)c(CN(C)C(=O)CCC#N)c1 +CCOCCOc1ccc(Cl)cc1NC(=O)C1CCCO1 +Cc1n[nH]c(C)c1CCC(=O)NCC1(N2CCOCC2)CCCCC1 +COc1ccc2nc(-n3nc(C)cc3NC(=O)C3CCC3)sc2c1 +Cc1ccc(S(=O)(=O)C2(C(=O)NC(C)c3ccccc3)CC2)cc1 +O=C(NCCNC(=O)C1CC1)c1cc2c(s1)CCCC2 +CC(=O)c1csc(C(=O)N2CCOCC2C2CC2)c1 +COc1ccccc1OCC(=O)Nc1ccc(CO)cn1 +Nc1ccc(Cl)c(NC(=O)c2c(F)cccc2Cl)c1 +Cc1cc(NCCCc2c(C)n[nH]c2C)n2nc(C)cc2n1 +CCN(Cc1nnc(C2CC2)o1)C(C)c1ccc(C#N)cc1 +CC(=O)Oc1cccc(NCc2ccccc2C)c1 +CC(=O)Nc1ccc(C(=O)Nc2nc(-c3cccs3)cs2)cc1 +COc1ccc(OC)c(C(O)CNC(=O)CC(C)C)c1 +CCNC(=O)C1CCCN(c2nc(C)nc3sc4c(c23)CCC4)C1 +COCc1ccccc1C(=O)Nc1ccccc1N(C)C +COc1ccc(COc2ccccn2)c(Br)c1OC +O=C1CN(C(=O)CCc2ncc(-c3ccccc3)o2)CCN1 +O=C(C1CC1)N1CCC(c2cc(O)nc(-c3cnccn3)n2)CC1 +CCNS(=O)(=O)c1ccc(F)c(C(=O)N(C)C(CC)CC)c1 +O=C(NCC1CC1)C1CN(Cc2cccs2)CC2OCCC21 +CCC(=O)NCCCOC1CCCc2ccccc21 +COc1ccc(NC(=O)c2ccc3c(c2)CCO3)c2cccnc12 +Cn1nc2n(c1=O)CCN(S(=O)(=O)c1ccc(C#N)cc1F)C2 +Cc1cc(NS(=O)(=O)c2ccc(N3CCCCC3=O)cc2)ccn1 +O=C(NCC1CN2CCCCC2CO1)NCC1(O)CCCCCC1 +O=C1c2ccccc2C2=Nc3ccccc3OC12O +C=CCNS(=O)(=O)c1cccc(C(=O)Nc2cccc(F)c2)c1 +CC1=C(C(=O)OCC(F)(F)F)C(c2ccc(F)cc2)NC(=O)N1 +CCNC(=O)CNC(=O)c1cc2ccccc2cc1OC(F)F +O=C(Cn1nnc2ccccc21)Nc1ccc(F)c(F)c1 +CC(=O)c1ccc(OC(=O)c2ccc3c(c2)[nH]c(=O)n3C)cc1F +CNC(=O)c1cccc(CNc2cc(C(=O)OC)cc(F)c2C)c1 +CCOC(=O)CCC(C)NC(=O)Nc1ccc(C#N)cc1 +Cc1nc2ccccc2n1CC(=O)NCc1cccnc1-n1cccn1 +COc1cc2c(cc1OC)CN(C(=O)COc1ccccc1)CC2 +CC(=O)Nc1ccc(Cl)c(NCc2ncc(-c3cccs3)o2)c1 +N#Cc1ccc(F)c(COC(=O)COc2ccccc2)c1 +CC(=O)NC1CCCN(C(=O)c2c(C)noc2C(C)C)C1 +CC(=O)N1CCc2cc(Nc3cnc4ccccc4n3)ccc21 +O=C(NCc1cccc(CO)c1)N1CCN(Cc2ccon2)CC1 +CCc1nc(COC(=O)c2ccc3c(c2)OCC(=O)N3)cs1 +CC(=O)Nc1ccc(SCc2nnc(C(C)C)o2)cc1 +Cc1noc(C2CC2)c1NC(=O)c1ccc(NC(=O)C2CC2)cc1 +CCC1Nc2cc(OC)ccc2N(COC)C1=O +CCC(CC)(CC)NC(=O)NC1CCN(S(=O)(=O)C2CC2)CC1 +Cc1c(Cl)c(Cn2cnc(C#N)n2)nc2ccccc12 +CCN(CCO)C(=O)C(C)NC(=O)c1ccc(C(C)(C)C)cc1 +CC(=O)NC(C(=O)Oc1ccc(F)cc1)C(C)C +Cc1ccc(C(C)NC(=O)c2cnn(-c3ccncc3)c2C)o1 +CC(c1cccnc1)N(C)CCOc1cccc(F)c1 +CCOC(=O)c1c(NC(=O)CCc2ccco2)sc(C)c1C +CC(=O)Nc1ccccc1CNc1nnc(CC(C)(C)C)o1 +O=C(c1cnn2ncccc12)N1CCCc2ccccc21 +CC(=O)c1cccc(-n2c(CCc3ccccc3)n[nH]c2=O)c1 +CCS(=O)(=O)N1CCCC(COCc2ccccc2)C1 +O=C(C1CC1(Cl)Cl)N(Cc1ccccc1F)C1CC1 +CC1(O)CCN(C(=O)c2ccnc(N)c2)CC1Cc1ccccc1 +CNS(=O)(=O)c1ccc(-n2cncn2)c(N)c1 +CCOc1ccccc1NC(=O)CSc1cc(C)nc2ncnn12 +CC1CCN(C(=O)c2ccccc2NC(=O)c2cccnc2)CC1 +Cn1cc(C(N)=O)cc1C(=O)NC1CCCc2ccccc21 +CCS(=O)(=O)N1CCCC(C(=O)NCC2CCCO2)C1 +Cc1nc(NC(C)c2ccc(-n3cncn3)cc2)c2nc(C)oc2n1 +CCOc1ccc(C(C)NC(=O)N2CCC(C(N)=O)CC2)cc1 +O=C(COC(=O)c1ccc2c(c1)OCO2)c1ccccc1 +COc1cc(C)c(Cl)c(C)c1COC(=O)CN +COc1ccccc1NC(=O)c1cc(C)nc2c1c(C)nn2C +CCC(=O)N1CCc2sc(C(=O)NCCCOC)cc2C1 +Cc1ccnc2nc(C(=O)Nc3ccccc3-n3cnnn3)nn12 +COc1ccncc1NC(=O)C1CCCN1C(=O)OCC(F)(F)F +O=C(Nc1ccc(Br)cn1)c1ccc2nccnc2c1 +Cc1cc2ncc(C(=O)NC(C)c3cccc4ccccc34)c(C)n2n1 +Cc1ccsc1CNC(=O)CSc1nncs1 +CC(C)(C)OC(=O)N1CCCC(Nc2ccn(CC(F)F)n2)CC1 +CC(C)N(C(=O)CCCc1nc2ccccc2s1)C1CCOCC1 +Cn1cc(C(=O)Nc2ccc(N3CCCC3=O)cc2)c(C(C)(C)C)n1 +N#Cc1ccc(NC(=O)NCc2cccnc2)cc1 +CN(Cc1ccccc1)C(=O)c1cc2c(=O)n3ccccc3nc2s1 +COC(=O)c1ccc(OC)cc1OC(=O)C1CC2CCC1C2 +CSc1nc2nnc(-c3nc4ccccc4[nH]3)c(N)n2n1 +Cc1cc(C)n(CC(C)Nc2nc(C)nc3sccc23)n1 +O=C(Cn1cnnn1)N1CCN(c2ncc(Cl)cc2Cl)CC1 +CCOC(=O)c1c(C)oc2ccc(OC(=O)CC)cc12 +CCOC(=O)c1c(C)c(C(=O)NCc2ccc(OC)cc2)c(C)n1C +C=CCN(Cc1cccc(C#N)c1)C(=O)c1c[nH]c2cccc(F)c12 +CCNc1nnc(SC(C)C(=O)Nc2cccc(Cl)c2)s1 +O=C(Nc1nnc(C2CCCCC2)s1)c1ccc(F)cc1 +CN(C)c1ncc(C(=O)NCCc2cccs2)cn1 +O=C1CCC(C(=O)N2CCN(S(=O)(=O)C3CC3)CC2)N1 +CCCc1nc(CNc2cc(CO)ccc2Cl)cs1 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1cccnc1 +CCOc1cc(C)ccc1NC(=O)C1Cc2ccccc2C(=O)O1 +CCOc1cccc(NCC(=O)Nc2c(C)cccc2C)c1 +CCOC(=O)c1nnn(-c2cccc(C)c2C)c1N +CCOC(=O)C1CCN(S(=O)(=O)c2cncc(N)c2)CC1 +COc1ccc(CNC(=O)c2cn(-c3cccc(Cl)c3)nn2)cc1 +COCc1noc(-c2ccc(N(C)Cc3nccs3)nc2)n1 +CCn1nccc1NS(=O)(=O)c1cc(Cl)ccc1C +CCOC(=O)CC(C)CNC(=O)c1cc2c(C)cc(F)cc2[nH]1 +CNC(=O)c1ccc(C)c(-n2cnc3cccnc32)c1 +Cc1cc(NC(=O)CN2CCOc3ccccc32)n(C)n1 +CC(NC(=O)CCSc1ccccn1)c1ccccc1 +CCn1cc(Cl)c(C(=O)Nc2ccc(F)cc2)n1 +CN1CC(NC(=O)c2ccc(F)cc2Br)CCC1=O +CC(C)CC(=O)N1CCN(C(=O)c2cc3cccnn3c2)CC1 +Cc1nc(CN(C)S(=O)(=O)Cc2ccccc2Cl)cs1 +COc1cc(C(=O)NCC(C)c2ccc(F)cc2)nn1C +CC(C)(C)C(NC(=O)Nc1ccn(CCc2ccncc2)n1)C(N)=O +Cc1nnc2sc(-c3ccc(CNC(=O)c4ccco4)cc3)nn12 +CC1CCCC(NC(=O)Cn2c(=O)[nH]c3ccccc32)C1C +CCCc1nnc(NC(=O)c2cc3sccc3n2C)s1 +COCCCNC(=O)c1cccc(Oc2ccccn2)c1 +CCN(c1ccc(C(=O)NCc2ccco2)cc1)S(C)(=O)=O +Cc1n[nH]c(C)c1NC(=O)CSc1cc(Cl)ccc1Cl +Cn1c(N2CCCN(C(=O)CC3CCCC3)CC2)cc(=O)n(C)c1=O +CN(C)C(=O)Cn1c2c(ccc1=O)CCN(S(C)(=O)=O)CC2 +CCc1nnc2ccc(NC(=O)NC3CCCCC3)cn12 +Cc1noc(CCCC(=O)NC(C)c2ccncc2)n1 +COc1cc(C(=O)NC(C)c2n[nH]c(C)n2)c2ccccc2n1 +CN(C)c1ccc(C(=O)Nc2cccc(F)c2)cc1F +CCNC(=O)c1cccc(CNC(=O)c2ccc3[nH]cnc3c2)c1 +Clc1cc(Cl)cc(NCc2ccccn2)c1 +CC(C)c1ccccc1NC(=O)C1(C#N)CCCC1 +CCc1c(C(=O)NC(C)C)cnn1Cc1ccccc1 +Cc1ccc(N2CCN(c3nnnn3-c3ccccc3)CC2)c(C)c1 +Cc1ccc2[nH]cc(-c3nc(N)nc4[nH]ncc34)c2c1 +CN(C)S(=O)(=O)N(C)C1CCC(c2ccccc2)CC1 +CN(C)C(=O)CN(C)C(=O)c1cn(C)nc1C(C)(C)C +Cn1ccc(NC(=O)Cc2ccc3c(c2)CCC(C)(C)O3)n1 +COC(=O)CN(C(=O)Cc1ccccn1)C(C)C +COC(=O)C1(NC(=O)CN2CCCCCC2=O)CCCCC1 +CS(=O)(=O)N(CC(N)=O)c1ccc(C(F)(F)F)cc1 +CCCn1ncc(C(=O)NCCS(=O)(=O)N2CCCC2)c1C +Cc1cccc(CCC(=O)NC2CCC(=O)CC2)c1 +CCOC(=O)c1cnc(Cc2ccc(F)cc2)nc1N +CCC(CC)NC(=O)c1cccc(NC(=O)C2CC2)c1 +COc1ccc(C(=O)N2CCCCC2C(C)O)c(F)c1 +Nc1cc(S(=O)(=O)NCc2cccs2)ccc1O +COc1ccc2[nH]c(-c3ccnc(OC)c3C#N)cc2c1 +Cc1noc(CCCC(=O)NCc2ccc(-n3cncn3)cc2)n1 +CCc1cnc(C)nc1NCCN(C)S(C)(=O)=O +COc1ccc(CCCNc2ccc(S(N)(=O)=O)cc2)cc1 +CC(C)Cn1cc(NC(=O)N2CCOCC2C2CC2)cn1 +CCOC(=O)CNS(=O)(=O)c1cc(C)ccc1F +Cc1ccc(C)c(OC(=O)COc2ccccc2C#N)c1 +Cc1cccc(OCC(=O)NCc2cccnc2)c1C +O=c1[nH]c2[nH]c(Nc3ccc(F)cc3)cc(=O)c2s1 +Cc1cccc(NC(=O)CNC(=O)NCc2ccccc2F)c1C +Cc1ccccc1C(=O)Nc1sc2c(c1C(=O)NC1CC1)CCC2 +O=C(CSc1nnc(NC2CC2)s1)c1c[nH]c2ccccc12 +COC(=O)CCNC(=O)Nc1cccc(OC)c1 +Cc1ccc(C)c(SCC(=O)NC2(c3noc(C)n3)CCCC2)c1 +N#CCCN(CCC#N)C(=O)c1cc(Cl)cc(Cl)c1 +Cn1cnc(S(=O)(=O)N2CCCC(C)(C(N)=O)C2)c1 +CC(C)(C)NS(=O)(=O)Cc1cccc(Cl)c1 +Cc1ccc(N2CC(CNC(=O)Nc3cccc(C)c3)CC2=O)cc1 +Cn1nc(CNC(=O)C2CC=CCC2)cc1-c1ccncc1 +CCC(C)n1ncc(C(=O)N(C)Cc2ccc(OC)cc2)c1C1CC1 +O=C(C1CC1)N1CCC(n2c(=O)oc3ccc(F)cc32)CC1 +Cc1ccc2c(c1)OCCN2Cc1nc2sc(C)c(C)c2c(=O)[nH]1 +COC(=O)c1ccc(Oc2ccc3ncccc3c2)c(N)c1 +COc1ccc(Br)cc1CNc1nnnn1C +CCn1ccc(C(=O)Nc2nnc(Cc3ccc(C(C)C)cc3)o2)n1 +Cc1ccc(CNC(=O)c2cc(-c3ccccc3)n[nH]2)o1 +COc1ccc(C(O)CNc2cccc(Cl)c2)cc1F +CCOC(=O)Cn1nc(C)c2c(-c3cnn(C)c3)ccnc21 +CCCC1CN(C(=O)Nc2c(C)cc(Cl)cc2C)CCO1 +CC(C)COc1ccc(CN2CCOC(C(N)=O)C2)cc1 +CCCCC(=O)N(C)C(C#N)c1ccc(OC)cc1OC +CCN1CCN(C(=O)CCc2cc3ccccc3[nH]c2=O)CC1 +COc1cccc(Oc2ncccc2CNC(=O)N(C)C(C)C)c1 +O=c1c2ccccc2c(-c2ccccc2)nn1Cc1nc(C2CC2)n[nH]1 +CC(=O)NCC1CCCN(C(=O)NCc2cccc(NC(C)C)c2)C1 +CC(C)(C#N)NC(=O)c1cccc(OC(F)F)c1 +CS(=O)(=O)c1ccccc1-n1nnnc1S(C)(=O)=O +O=C(CN1CCN(c2nccs2)CC1)NCCCn1cccn1 +CC1CCN(C(=O)c2sccc2-n2cccc2)CC1 +Cc1ccc(S(=O)(=O)c2c(N)nc(C)[nH]c2=O)cc1 +CCN(Cc1noc(C2CC2)n1)Cc1nc2ccccc2c(=O)[nH]1 +CCC(CC)c1nc(C2CC2)c(C(C)(C)O)s1 +Cc1occc1CN(C)C(C)c1nc(C(C)C)no1 +O=C(c1ccoc1)N1CCC2(CC(OCc3ccncc3)CO2)C1 +CCOC(=O)c1sc2ncnc(N(CC)CC)c2c1C +Cc1cc(-c2nc(-c3cccc(O)c3)no2)c(C)o1 +CC(O)CNc1ccc(NC(=O)c2ccncc2)cn1 +Cc1cc(C(C)Nc2cc(F)ccc2N)c(C)s1 +NC(=O)C1Cc2ccccc2CN1C(=O)CCSc1ccccc1 +CN(C)S(=O)(=O)c1ccccc1CNC(=O)c1ccn(C)c(=O)c1 +CC(c1ccccn1)N(C)C(=O)CN1CCOC1=O +CCCc1cnc(C)nc1N1CCN(Cc2ccc(CC)cn2)CC1 +CCCN(CC1CC1)C(=O)Nc1cccnc1-n1cncn1 +CN(C)S(=O)(=O)c1ccccc1-c1ccc(O)c(Cl)c1 +CCCS(=O)(=O)c1cc2ccccc2oc1=O +COCc1cccc(NC(=O)c2nn3ccccc3c2Cl)c1 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+COc1ccc(NC(=O)Cn2ccc3c(NC(C)=O)cccc32)cn1 +CC(O)c1nc2cc(N)ccc2n1Cc1ccccc1F +Cn1nc(C(=O)Nc2ccc(-n3cnc4ccccc43)cc2)ccc1=O +CC1CC(C)CN(C(=O)c2cccc(NC(=O)c3ccccc3)c2)C1 +Cc1ncsc1C(=O)N(C(C)C)C1CCOCC1 +CCc1nn(C)c(OC)c1CNC(=O)N1CCCCC1c1cn[nH]c1 +O=C(c1ccc2ccccc2n1)N1CCOc2ccc(F)cc21 +COc1cc(F)c(S(=O)(=O)NCc2ccco2)cc1OC +O=C1CSc2ccc(C(=O)NCC(O)c3ccc(F)cc3)cc2N1 +CC(Sc1nnnn1Cc1cccs1)C(=O)c1ccc(F)cc1 +COc1cccc(C(=O)N(CCC(N)=O)Cc2ccccc2)c1F +CNc1nn2c(=O)c(-c3ccc(OC)cc3)nnc2s1 +N#CC1(NC(=O)CN2CCCc3ccccc32)CCCC1 +CCOC(=O)c1cnc(COc2ccccc2C)nc1N +COC(=O)CNCC1(O)CCCN(Cc2ccc(F)c(F)c2)C1=O +O=C(c1ccc[nH]1)N1CC2CN(Cc3cccc(F)c3)C(=O)C2C1 +Cc1nc(COC(=O)Cc2c(F)cccc2F)sc1C +COC(=O)C1CCN(C(=O)c2cn(CCC3CCCCC3)nn2)CC1 +Cc1ccc(CNC(=O)C(C)N2CCN(S(C)(=O)=O)CC2)cc1 +COC(=O)CNc1ncc(C(F)(F)F)cc1Cl +CC(C)COc1ccccc1-c1cc(C#N)c(=O)n(C)n1 +CC(C)c1nc(CCNC(=O)C2COc3ccc(F)cc3C2)cs1 +O=C(NCCc1nc2c(s1)CCCC2)c1ccc2[nH]cnc2c1 +Cc1c(C(=O)N2CCCCCC2)nnn1-c1nonc1N +CC(CNC(=O)Cn1c(=O)[nH]c2ccccc2c1=O)Cn1cccn1 +CC1CS(=O)(=O)c2cc3c(cc2C1=O)CCC3 +Cc1nc(C(=O)NC(C)COc2ccc(F)cc2)cs1 +Cc1ccc(NC(=O)Cn2c(=O)[nH]c(=O)c3ccccc32)cc1Cl +Cc1cc(CC2COCC2NC(=O)CCN2CCCCCC2=O)on1 +CCn1c(C2CCN(Cc3cccnc3)C2)nc2cccnc21 +CCN(CC(=O)NC)S(=O)(=O)c1ccc2c(c1)n(C)c(=O)n2C +Cc1nc(COc2ccc(CNC3CCCCNC3=O)cc2)cs1 +Cc1cccc(OCC(=O)N(Cc2ccsc2)C2CC2)c1 +CC(c1ccccc1Cl)N(C)C(=O)Nc1ccncc1 +Fc1ccc2sc(CNc3ccc4nnnn4n3)cc2c1 +CSc1nc(C)c(CCC(=O)OCC(C)(C)C)c(=O)[nH]1 +COCCN(c1cccc(F)c1C(C)O)C1CC1 +N#CCc1ccc(NC(=O)Cc2ccc(F)cc2)cc1 +O=C(Nc1ccncc1)N(CCO)Cc1ccc(Cl)c(Cl)c1 +COc1cc(Cl)ccc1C(=O)N1CCOC(C)(c2cnn(C)c2)C1 +CCNC(=O)N1C2CCC(C2)C1C(=O)Nc1ccccc1 +O=C(CCCSc1nc2ncccn2n1)c1cccs1 +Cn1cc(-c2nc(C(=O)N3CCCc4cccc(F)c43)cs2)cn1 +Cn1nc(COc2cccc(Br)c2)cc1N +CCC(CC)(CC)NC(=O)c1ccc(CNC(N)=O)cc1 +CC(=O)Nc1ccc(SCC(=O)Nc2ccccc2Cl)cc1 +Cc1nccc(CNC(=O)c2cn(-c3ccc(Cl)cc3)nc2C)n1 +CC(=O)N(C)CC(=O)NCC(c1ccccc1)c1ccccc1 +Cc1c(C(=O)N(C)Cc2ccccc2)cnn1-c1ccccc1 +O=C(NCCc1ccccn1)N1CCC(CN2CCOCC2)CC1 +Cc1cc(C)n(CC2CCN(C(=O)C3CCC3)CC2)n1 +CCC(NC(=O)C1OCCC1C)(C(N)=O)C(C)C +O=C(c1cc2c(cc1O)CCCC2)N1CCC(N2CCNC2=O)CC1 +COCc1nn2c(CO)c(-c3cccnc3)nc2s1 +CCN(C)C(=O)CCC(=O)Nc1ccc2c(n1)n(CC)c(=O)n2CC +CC(=O)NC(CC(=O)NCCc1ccco1)c1ccc(Cl)cc1 +Cc1ccccc1C(=O)N1CCN(c2cc(-n3cccn3)ncn2)CC1 +CC(=O)Nc1ccccc1OCC(=O)N1CCCC1c1cccs1 +CC(C)OC(=O)C1=C(C(C)C)N(C)C(=O)NC1c1ccncc1 +O=C(CSc1nn2cnnc2s1)Nc1ccc2c(c1)OCCO2 +COc1ccc(-c2noc(C3CC=CC3)n2)cc1OC +Cn1c(N)c(N2CCN(c3ccccc3)CC2)c(=O)[nH]c1=O +COc1cc(S(=O)(=O)Nc2ccccc2)c(OC)cc1N +CN(C)C(Cn1cncn1)=C1N=C(c2c(F)cccc2F)OC1=O +CCC1CN(C(=O)Cn2cc(C(F)(F)F)ccc2=O)CCO1 +CC(C)Oc1ccccc1-c1ccc(NCCN2CCOCC2)nc1 +CC(NC(=O)Cn1c(-c2ccccc2)noc1=O)c1ccccc1 +COc1ccc(O)c(C(=O)N(C)Cc2nc3ccsc3c(=O)[nH]2)c1 +Cc1ccc(-c2nc(CC(=O)NCCO)cs2)cc1 +Cc1cccc2[nH]c(CCC(=O)OCC3CC(=O)N(C4CC4)C3)nc12 +C#CCN1CCN(CC#Cc2ccccc2Cl)CC1 +Cc1ccc(CN(C)C(=O)COc2ccc(-n3cccn3)cc2)o1 +Nc1ccc(Cl)cc1C(=O)NC1CCC(O)CC1 +Cc1cccc(C)c1NC(=O)CS(=O)(=O)c1ccc(F)cc1 +COc1ccc(F)c(NC(=O)C2COc3ccccc32)c1 +CCCc1c(CO)nnn1-c1ccc(C(N)=O)cc1 +CCOc1ccc(OCc2c(CO)nnn2C(C)C)cc1 +COc1ccc(-c2csc(NC(=O)c3cc(C(C)=O)c[nH]3)n2)cc1 +Cc1nc2cc(NC(=O)c3ccccc3Cl)ccc2n1C +COC(=O)C1CCCCN1Cc1cnc(-c2cccnc2)s1 +CCNC(=O)COc1ccc(NC(=O)c2ccncc2)cc1 +Cc1nn(C)c2ncc(NC(=O)c3cccc4ccccc34)cc12 +Cc1cc(OCc2cccc(F)c2)ccc1NC(=O)C1CCC(=O)N1 +CC(=O)N(CC1CCCO1)c1nnc(-c2cnccn2)s1 +CC(=O)c1csc(NC(=O)c2cc(C3CCCCC3)no2)n1 +Cn1c(=O)c2c(nc3n(CCO)c(-c4ccccc4)cn23)n(C)c1=O +O=C(NC1CCCCC1)c1ncc(-c2ccccc2)o1 +CCN(CCC#N)C(=O)CSc1nncn1C +COc1ccc(CNC(=O)Cc2coc3cc(C)ccc23)cn1 +COc1ccnc(NC(=O)c2cc(Br)c[nH]2)c1 +COC(=O)c1ccccc1NC(=O)CCc1ccco1 +O=C(OCCNc1cccnn1)C1(c2ccc(Cl)cc2)CCC1 +CC(=O)NC(C)C(=O)NCC1(c2ccccc2)CC1 +CC(C)(C)NC(=O)CN1CCN(c2ncc(Cl)cc2Cl)CC1 +CC(=O)Nc1ccc(NC(=O)c2nc3ccccn3c2F)cc1 +Cc1ccc(C(=O)NCC(=O)N2CCCCCC2)cc1 +Cc1cc(C)c(CNC(=O)N2CCOC(C(N)=O)C2)c(C)c1 +COC(=O)C(C)Oc1ccc(CN2CCOCC23CCC3)cc1 +CCc1cc2c(N3CCC(n4cncn4)CC3)ncnc2s1 +COCC(NC(=O)c1cc(F)c(F)c(F)c1)C(N)=O +C=CCNc1nnc(SCC(=O)c2cc(F)ccc2F)s1 +CC(C)CCN(CCC(C)C)C(=O)c1ccn(C)c(=O)c1 +CCOC(=O)c1coc(N2CCC(n3nc(C)cc3C)C2)n1 +COc1c(Cl)cccc1NC(=O)C1CC2CCC1O2 +CC1CN(c2cc(N3CCCC3C(N)=O)ncn2)CC(C)O1 +Cc1nc(CC(=O)N2CCCC(CO)(Cc3ccccc3)C2)cs1 +N#Cc1cc(C#N)c(SCC(=O)Nc2ccccc2)nc1N +CCNC(=O)COc1cccc(NC(=O)c2ccc(O)c(Cl)c2)c1 +CCS(=O)(=O)c1ccccc1C(=O)Nc1cc(C)nn1C +CCn1cc(C(=O)NCc2noc(C)n2)c(=O)c2cc(Cl)ccc21 +CN(CCc1ccncc1)C(=O)NCCc1ccc(F)cc1 +COc1cc2c(c(Br)c1O)CNCC2 +Cc1cc(CNc2nnc(C3Cc4ccccc4O3)o2)c(C)o1 +CCNC(=O)C1CSc2nc(C)c(CC)c(=O)n2C1 +CCS(=O)(=O)c1ccc(S(=O)(=O)N=c2ccc(C)c[nH]2)cc1 +NC(=O)c1cc(N2CCCCC2)ccc1NC(=O)CO +O=C(Nc1ccc(C(=O)N2CCOCC2)c(Cl)c1)C1CCCO1 +CCN(CC)C(=O)CN(C)C(=O)c1cc(-c2cccc(Cl)c2)no1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1ccc(=O)n(C)n1 +CC(=O)N1CCC(CN(C)C(=O)C(C)Oc2cccc(C)c2)C1 +CC(C)NC(=O)Nc1nc2c(s1)CN(C(=O)C1CC=CCC1)CC2 +CC(NS(=O)(=O)c1cccs1)C(=O)N1CCN(C(C)C)CC1 +Cc1sc(=O)n(CC(=O)N2CC(C)OC(C)C2)c1C +COc1ccc(OC)c(CC2(c3ccccc3)NC(N)=NC2=O)c1 +COc1cc(C(=O)NCc2ccccc2C)nc2c(F)cc(F)cc12 +COCCn1c(-c2ccc(Cl)cc2)ccc(CO)c1=O +Nc1cccc(C(=O)Nc2ccc(Cl)c(F)c2)n1 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+CC(C)(C)n1cc(NC(=O)Nc2nccs2)cn1 +O=C1CCN(S(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)CC1 +CC1CCC(N(C(=O)c2ccc(C(=O)N(C)C)cc2)C2CC2)CC1 +CC(=O)NC(C)C(=O)N1CCC(Cc2cccc(F)c2)CC1 +Nc1cccc(-c2n[nH]c(Cc3cc(F)ccc3F)n2)c1 +CC(CNC(=O)Nc1nnc(-c2ccsc2)s1)Cn1cccn1 +Cc1cc(C)n(CCCNC(=O)c2cc3c([nH]c2=O)CCC3)n1 +CC(Nc1ccc(Cl)cc1)C(=O)Nc1ccc(C(N)=O)cc1 +NC(=O)c1cccc(CNC(=O)CCc2cccs2)c1 +CCC(C)NC(=O)c1ccc(NC(=O)NCCC(C)C)cc1 +Cc1cc(C)n2nc(Sc3nccnc3C#N)nc2n1 +CC(=O)Nc1ccc(C(N)c2nc3ccccc3s2)cc1 +CCCCCC(C)NC(=O)NCC(=O)N1CCCCC1 +Cc1cc(C)c(C(=O)N(C)Cc2cccc(C#N)c2)c(=O)[nH]1 +CCOc1ccc2c(c1)C(c1cccc(O)c1)NCC2 +O=C(CCc1ccccc1)NCC1(O)CCc2ccccc21 +Cc1cccc(C(=O)N(CC2CC2)c2cc(Cl)ccc2C#N)n1 +CCC(=O)Nc1nnc(S(=O)(=O)N(C)Cc2ccco2)s1 +Cc1ccc2ncc(C(=O)Nc3c(C)cccc3C)n2c1 +CNS(=O)(=O)c1cccc(NC(=O)C2CC=CCC2)c1 +Cc1cc(N)nc(SCC(=O)N(C)C(C)C)n1 +O=C(CNC(=O)NCc1cscn1)Nc1ccc(Cl)cc1 +COc1ncccc1NC(=O)C1CCN(c2ccc(Cl)cn2)CC1 +CC(Nc1ncnc2sc(-c3ccccc3)cc12)c1nncn1C +COc1ccc(C)cc1-c1nc2c(CO)cccn2c1N +CN(Cc1ccc(C#N)cc1)S(=O)(=O)c1cccc2cnccc12 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+CCC(C)NC(=O)C1CCN(c2ccc(Cl)cc2)C1=O +COc1ccc(NC(=O)COc2cccnc2N)cc1 +COCc1cccc(NC(C)c2nc3sc(C)c(C)c3c(=O)[nH]2)c1 +CC1Oc2c(C(=O)N3CCCC(n4cncn4)C3)cccc2C1C +CCN(C(=O)COC1CCCC(C)C1)C(C)c1cccc(O)c1 +CN(C)C(=O)Cn1cc(C(=O)NCc2ccc3c(c2)CCC3)nn1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)CSc1nnnn1C +Cc1ccc(CC(=O)N(C)CC(=O)Nc2c(C)cccc2C)cc1 +CCN(CC(F)(F)F)C(=O)c1cc(S(C)(=O)=O)ccc1C +CCc1ccc(CC2CN(CCO)c3cc(O)ccc3O2)cc1 +Cc1ccc(-c2ncc(NC(=O)c3ccc(C#N)cc3)cn2)cc1 +COC(=O)c1ccc(NC(=O)c2cccc(OC)c2)c(C)c1 +CNC(=O)NCC(=O)Nc1ccc(NC(=O)CC(C)C)cc1 +Cc1ccccc1Cn1cc(NC(=O)c2csnc2C)cn1 +O=C(COc1ccccc1F)NCC(O)C1CCCCC1 +COc1cccc(NC(=O)c2cnn(-c3ccccc3)c2F)c1 +Cc1cc(N2CCN(Cc3ncccc3C)CC2)n2nc(C)cc2n1 +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)NCCC1CCCCC1 +CNS(=O)(=O)c1ccc(-c2nc(-c3ccccn3)no2)o1 +O=C(c1cc2c(s1)CCC2)N1CCn2c(nnc2C2CC2)C1 +O=C(NCc1cccnc1)c1cc2ccccc2cc1O +COCC(C)NC(=O)c1c(-c2ccccc2Cl)noc1C +O=C(CCNC(=O)c1cccc2cn[nH]c12)NCc1ccccn1 +O=C(NCc1csc(=O)[nH]1)c1cccc(-c2ccoc2)c1 +Cc1ccc(CN(C)C(=O)CSc2nnc(C(C)(C)C)n2N)o1 +Cc1noc(C)c1C(=O)N1CCSc2ccc(Cl)cc21 +Cc1cc(-c2nnc(NC(=O)c3snnc3C)o2)c(C)o1 +CCCCSc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 +CCc1cccc(CC)c1NC(=O)c1ccccc1N +CCC(C)C(=O)Cn1cnc2c(cnn2C(C)C)c1=O +Fc1ccc(NCc2ccccc2OC(F)F)nc1 +CCCC1CN(C(=O)C(C)Oc2cccc(C(C)=O)c2)CCO1 +CCCCOC(=O)C1=C(C)Nc2nnnn2C1c1ccccn1 +Cc1cnccc1NC(=O)C1CCCCN1C(=O)OC(C)(C)C +Cc1ccc(-c2ccc(C(=O)N3CCCCC3CNC(N)=O)s2)o1 +COc1ccc(CC(=O)N2CCC(O)CC2)c(Cl)c1 +CCOc1ccc(C(=O)CCOC)cc1Br +COc1ncccc1CN1CCC2OCCC2(C(=O)NC2CC2)C1 +CCOC(=O)c1cc2c(s1)CN(C(=O)OC(C)(C)C)CC2 +COc1cc(C)c(C(C)C(C#N)N2CCCC2)cc1C +CCc1nnc(NC(=O)Cc2ccc(C(F)(F)F)cc2)s1 +COCC(C)NCc1cc(=O)[nH]c(-c2csc3c2CCCC3)n1 +NC(=O)C1CCN(C(=O)C2(c3cccc(Cl)c3)CCCCC2)CC1 +CC(C)C(NC(N)=O)C(=O)Nc1ccccc1N1CCCC1 +O=C(Nc1ccc2[nH]nnc2c1)c1c[nH]nc1-c1ccccc1F +CCC(=O)c1ccc(OCC(=O)NC2(C#N)CCCCC2)cc1 +CCc1ccccc1NC(=O)CN(C)C(=O)c1c[nH]c2ccccc12 +CCS(=O)(=O)N1CCC(NS(C)(=O)=O)C1Cc1ccccc1 +CCC(=O)Nc1cccc(C(=O)NC(C)C(=O)OC)c1 +Cc1cc2c(cc1C)OC(C(=O)NCc1nc(-c3ccco3)n[nH]1)C2 +O=c1oc2ccccc2n1CCOc1ccc2ncccc2c1 +CCC(C)C(NC(=O)c1ccccc1)C(=O)NC(C)c1ccc(C)o1 +N#Cc1cnc2c(c1)c(C#N)cn2Cc1ccccc1 +FC(F)(F)c1nc2cccnc2n1Cc1ccccc1 +Cc1cc(S(=O)(=O)n2ccnc2C(C)C)ccc1F +CCCCN(C)C(=O)CCc1c(C)nc2nc(N)nn2c1C +Cc1ccc(C(=O)N(C)Cc2nnc3ccccn23)cc1F +Cc1ccc(C)c(NC(=O)C(C)n2c(C)ccc(C#N)c2=O)c1 +Cc1ccc2c(c1)C(=O)OC1(O)c3ccccc3C(=O)N21 +CCOc1cccc(C2NC(=O)c3ccccc3N2)c1OC +Cc1cccc2c1N(CCc1ccccc1)C(=O)C21OCCO1 +Cc1nc(C)c(C(=O)Nc2nc(-c3ccccc3)c(C)s2)s1 +CC(=O)N(CCc1ccccc1)CC(=O)N(C)c1ccccn1 +COCCOc1ncccc1C(=O)N1CCCc2c(C)ccc(F)c21 +CCC(c1ccccc1)c1nnc(SCOC)o1 +Cc1ccc(-c2cc(C(=O)N3CCCC3c3nccs3)[nH]n2)o1 +CCOC(=O)N1CCN(C(=O)c2cc3sccc3n2C)CC1 +Cc1cc(C(=O)NCc2cnc(C)s2)c(C)o1 +Cc1nn(C)c2ncc(NS(=O)(=O)c3ccc(C(C)C)cc3)cc12 +NC(=O)C1CCCCCC1NC(=O)c1scnc1C1CC1 +CC(C1CC1)N(C(=O)Nc1cccc(C(=O)NC2CC2)c1)C1CC1 +Nc1ccc(Cl)cc1C(=O)N1CCNC(=O)CC1 +O=C(Cc1ccsc1)NCc1noc(-c2ccsc2)n1 +CCOC(=O)CCC1NCCc2cc(C)c(F)cc21 +Cc1cccnc1NC(=O)CCc1ccccc1F +COCCn1cnnc1SCC(=O)Nc1nc(C)cs1 +COc1ccc(NC(=O)OCC(C)C)cc1OC +CCOc1ccc(NS(=O)(=O)CC)cc1CO +CCc1ccc(S(=O)(=O)N(C)c2ccc(F)c(N)c2)cc1 +CCOC(=O)C(CNc1ccccc1)c1ccccc1 +COc1cc(CNC(=O)c2ccc(C)o2)ccc1O +NC(=O)NCC(=O)Nc1cccc(Br)c1 +CCNC(=O)c1ccc(-c2ccnc3c2ccn3C)cc1 +CC(C)C(NS(=O)(=O)c1ccc(F)cc1)c1nnc2ccccn12 +COc1ccc(OC)c(NC(=O)NCc2cccnc2)c1 +CC1(C)CCCN1C(=O)c1cc(Cl)ccc1O +CCN(Cc1ccncc1)c1ccc(-c2nc(CC(C)C)no2)cn1 +O=C(C1CC=CCC1)N1CCN(CC(O)c2ccco2)CC1 +COc1ccc(N(C)C(=O)Cc2ccc(F)c(F)c2)cn1 +COCc1cccc(NCC(=O)NC(C)(C)C)c1 +O=C(Nc1cn[nH]c1)Nc1cnc2ccccc2c1 +COCCOc1ncccc1NC(=O)NCc1ccc(F)cc1 +Fc1cc(F)c(NCCc2ccccn2)cc1F +CCNC(=O)c1c(C)nc(N)nc1C(CC)Oc1cccc(C)c1 +CC(=O)Nc1ccc(-n2cnc(C(=O)NCc3cccnc3)c2)nc1 +CCn1cnnc1CNC(=O)c1cc(C(C)C)n(C(C)(C)C)n1 +COc1ccc(CNC(=O)C2CCCCC2)cc1OC +C#CCN(C)C(=O)c1ccc(-c2ccc3c(c2)OCCO3)s1 +CCNC(=O)C1CCN(c2ccc(F)cc2)C1=O +CCN(CC)C(=O)c1cccc(NC(=O)c2ccc(C#N)cc2)c1 +Cc1cc(NC(=O)CSc2nnc(C3CC3)n2N)no1 +CC1c2ncc(Cn3cncn3)n2CCN1C(=O)N(C)C +Cn1nc(C(=O)NCCNc2cnccn2)ccc1=O +CC(NC(=O)CCC(=O)N1CCOCC1)c1ccc(C#N)cc1 +CC(C)CCNc1nnnc2c1cnn2-c1ccccc1 +CCN(CC)C(=O)Cn1c(=O)n(CC(C)C)c(=O)c2sccc21 +CC(=O)N(Cc1ccc(NC(=O)NCCCO)cc1)C1CC1 +O=C(NCC1(COc2cccnc2)CC(O)C(O)C1)C1CC1 +CCOC(=O)CC(C)CNC(=O)c1cc(F)ccc1C +O=C(NCC(=O)N1CCOCC1C1CC1)c1cccnc1 +C=CCNC(=O)c1cnc2c(c1)c(=O)n(C)c(=O)n2C +CCn1c(=O)c(C2C(=O)Nc3ccccc32)nc2ccccc21 +O=C(NCC(F)(F)F)c1ccc(=O)n(Cc2ccccc2)n1 +CN(Cc1ccccn1)C(=O)Nc1cccc(Br)c1 +CCOc1cc(C)ccc1NC(=O)C1CC2CCC1O2 +O=C(Cn1c2c(sc1=O)CCCC2)N1CCCc2ccccc21 +CCOC(=O)C(NC(C)=O)(Nc1cccc(Cl)c1)C(F)(F)F +CC(=O)Nc1ccc2c(c1)C(C1CCCO1)NCC2 +CCNC(=O)N(CCCN1CCOCC1)Cc1ccc(F)cc1 +CCc1[nH]c(C(=O)NC(C)c2ccncc2)c(C)c1C(=O)OC +CCCN(C)C(=O)NCCc1ccc(OC)cc1OC +Cc1noc(C)c1CC(=O)N1CCN(C(=O)c2ccccn2)CC1 +CC(=O)Nc1ccc(S(=O)(=O)c2ccc(N)cc2)cc1 +CC(=O)NC(CC(=O)NCCN1CCOCC1)c1cccs1 +COc1ccc(NC(=O)CNC(=O)c2cc(C)cc(C)c2)cn1 +Cc1cccc(OCCc2nc(C)c(CC#N)s2)c1 +CCn1c(SCC(=O)c2ccccc2)nnc1-c1ccoc1C +Cc1ccc(CNC(=O)c2ccc(Cn3cccn3)cc2)n1C +COc1cc(CCNC(C)=O)cc(OC)c1OC +CCOCCSc1nnc(-c2ccccc2OC)o1 +CC(C)C(=O)NCCNS(=O)(=O)c1ccc(C(C)(C)C)cc1 +CCC1CCCCN1C(=O)Cn1ncc2ccccc2c1=O +CCN(C(=O)CSc1ncn[nH]1)c1ccccc1 +CC(C)C(=O)Nc1cccc(-c2nn3cnnc3s2)c1 +CC1CN(C(=O)c2cnn(-c3ccccn3)c2C(F)(F)F)CCO1 +CN(Cc1cccnc1)C(=O)CCc1nc2ccccc2s1 +Cc1ccc(CN(C)C(=O)COc2ccccc2C#N)c(C)c1 +CC1Sc2ccc(S(=O)(=O)NC3CCCCC3)cc2NC1=O +O=C(NCCOc1ccccc1)C1=C2c3ccccc3C(=O)N2CC1 +Cc1cc(C(N)=O)ccc1NC(=O)CCOCC(C)C +Cc1cccc(C(=O)N2CCCC(c3nc4ccccc4[nH]3)C2)c1 +O=C(Nc1ccc(-n2ccnc2)nc1)C1CCCCC1 +COc1ccccc1-c1n[nH]c(NC(=O)CCc2ccc(C#N)cc2)n1 +COc1cccc2ccc(-c3nccn3CCn3cc(C)nn3)nc12 +O=C(NCc1nc(C2CC2)no1)Nc1ccccc1C(F)(F)F +CCCn1c(SCC(=O)Nc2ccnn2C(C)C)n[nH]c1=O +CC(=O)N(C)c1cccc(NC(=O)c2ccc(OCC(F)F)nc2)c1 +CN(CC(N)=O)C(=O)c1cn(-c2ccc(Br)cc2)cn1 +O=C(Nc1cccnc1)c1c(F)cc(Br)cc1F +CCC(CC)n1ncc(C(=O)Nc2ccc3c(c2)COC3)c1C +CCNC(=O)C(C)NC(=O)NCC(=O)NC(C)(C)C +Cc1cc(S(=O)(=O)N2CCN(C(=O)CC(C)C)CC2)c(C)s1 +O=C(Nc1nnc(C2CC2)s1)c1ccc2c(c1)C(=O)c1ccccc1-2 +CCn1c(SCc2n[nH]c(=O)[nH]2)nnc1-c1ccccc1OC +O=C(CCNC(=O)c1ccc2ncnn2c1)Nc1nccs1 +Cc1cc(C)c(C(=O)OCC(=O)Nc2cc(C)nn2C)c(C)c1 +CCCNC(=O)c1cc2cc(S(=O)(=O)N(C)C)ccc2n1CC +CSc1cccc(-n2nnnc2-c2cccc(N)c2)c1 +CC(C)CN(C(=O)Cn1nc2ccccn2c1=O)C(C)C +Cc1cc(C)c(CNC(=O)CCc2ccncc2)c(C)c1 +Cc1nn(C)cc1CN(C)CCc1ccc(F)cc1 +Cc1cnn(-c2ccc(C(=O)Nc3c(C)cccc3C)cc2)c1 +CCOC(=O)c1cn(Cc2ncc(CC)o2)c2nc(C)ccc2c1=O +Cc1cc(C)c2c(c1)CCNC2c1cccnc1F +COc1ccccc1CNC(=O)COC(=O)c1ccc(C#N)cc1 +COc1ccc(C(=O)COC(=O)c2ccc(O)cc2O)cc1OC +CN(C)c1ccccc1NC(=O)C1CC(=O)N(Cc2ccccc2)C1 +COC(=O)c1ccc(Cn2cnc3ccccc32)cc1 +CCNC(=O)c1ccc(NS(=O)(=O)CC)cc1 +Cc1cc(NC(=O)c2cnn(C)c2)c2ncccc2c1 +CCCCCNC(=O)N1CCCC(CNC(N)=O)C1 +Cn1c(COc2ccc(Cl)cc2)nnc1SCCn1cccn1 +COCCCNC(=O)CN1CCOc2ccc(F)cc21 +Cc1noc(C)c1COC(=O)CCc1nc2ccccc2s1 +COc1cc(CN2CCN(c3c(C)n[nH]c3C)CC2)cc(OC)c1 +Cc1ccc(-n2cnnc2S(=O)(=O)Cc2ccon2)cc1Cl +COc1ccc(C(=O)N(Cc2c(F)cccc2Cl)C2CC2)cc1 +COc1ccc(SC(C)C(=O)Nc2ccc3c(c2)COC3)cc1 +Cc1cc(C(=O)Nc2nc(C(=O)N3CCc4ccccc43)co2)no1 +CCOC(=O)N1CCCN(C(=O)COc2ccc(C)c(C)c2)CC1 +CCN(C(=O)CSc1ncccc1N)C1CC1 +NC(=O)CSc1nnnn1-c1ccc2c(c1)OCCO2 +Cc1ccc(C2(O)CCN(c3cnccn3)C2)cc1 +Cc1cc(-c2csc(S(=O)(=O)N3CCCCC3)c2)on1 +CC(C)(C)N(CCO)S(=O)(=O)c1ccc(Cl)cc1 +CCC1CCCN(C(=O)c2ccc3ccccc3n2)C1 +Cc1cccc(CN(C2CC2)S(=O)(=O)N2CCCC(C)C2)c1 +Cc1cc(C)cc(NC(=O)CCCNC(=O)c2cccs2)c1 +CC(=O)c1cccc(OC(=O)CCCc2cccs2)c1 +CCc1ccc(C(=O)N2CCC(C(C)N3CCOCC3)CC2)s1 +CCOc1ccc(-c2c(C)noc2N)cc1OCC +N#Cc1c(F)cccc1N1CCN(C(=O)c2ccccc2Cl)CC1 +CCOCCCNC1=NS(=O)(=O)c2ccccc2N1C +CNC(=O)Cn1nnc(CO)c1-c1ccc(Cl)cc1 +O=C(CSc1ccccc1)Nc1nc(-c2cccc(O)c2)cs1 +CC(=O)NCCC(=O)NCCNC(=O)c1ccoc1 +CC(=O)N1CCc2cc(NC(=O)c3ccc(C(F)(F)F)cc3)ccc21 +Cc1nc(COc2cccc(S(C)(=O)=O)c2)nc2ccccc12 +CC(=O)N1CCOCC2(CN(Cc3ccncc3)CCO2)C1 +CS(=O)(=O)N1CCCC(c2nc3ccccc3o2)C1 +CC(C)(C)NC(=O)C1Cc2ccccc2CN1Cc1cccs1 +Cc1ccncc1NC(=O)NCc1ncc(C(C)(C)C)o1 +O=C(Cn1nc2ccccn2c1=O)N=c1[nH]nc(-c2ccccn2)[nH]1 +CC(C)CNC(=O)CCN(C(=O)c1cnccn1)C(C)C +Cc1cnn(CCc2nnc(Nc3ccc(F)cc3)s2)c1 +CCOCc1ccccc1NC(=O)NCCc1ccc2c(c1)OCO2 +Cc1noc(CN2CCCC(CN3CCOCC3)C2)n1 +CC(O)CNC(=O)c1ccccc1SCC#N +C#CCN1CCC(C(=O)NCc2ccccc2OC(C)C)CC1 +O=C(c1sccc1OC(F)F)N1CCC(O)(C(F)(F)F)CC1 +Cc1nnc2n1CCN(C(=O)c1cc(F)ccc1F)C2 +COc1ccccc1C(C)N(C)C(=O)c1cc(-c2cccnc2)on1 +O=C(CN1CCOCC1)Nc1cccc(C(=O)N2CCCCC2)c1 +CCc1ccc(Cl)c(CC)c1NC(=O)NCC(O)COC +CC1CC(c2ccc(F)cc2)CN1C(=O)c1cscn1 +O=C(CCc1nc(-c2ccco2)no1)NCc1cccc2ccccc12 +CCOC(=O)C(C)Nc1nc2cc(F)ccc2s1 +Cc1cc2c(=O)n(C(C)Cc3ccccn3)cnc2s1 +COc1nn(C)c(C)c1NC(=O)NCCCc1c(C)noc1C +COC(=O)c1noc(C(=O)N(C)c2ccccc2)c1N +Cc1nnc(SCc2cc(Br)ccc2F)s1 +CC(C)c1cc(NC(=O)CCc2ccccc2O)[nH]n1 +Cc1n[nH]cc1NC(=O)c1cc2c(nc3sccn32)s1 +CCc1ccc(NC(=O)CCc2nc(C)no2)cc1 +O=C(COc1cccc2cccnc12)c1ccc2c(c1)OCCO2 +CC(C)c1cccc(N2CC(C(=O)NCc3ccco3)CC2=O)c1 +Cc1cccc(C(=O)N2CCc3cc(S(=O)(=O)N(C)C)ccc32)c1 +COc1cc(C(=O)N2CCOCC2)cc2c1OCCO2 +CC(C)c1nnc2n1CCN(C(=O)C1CCCCC1C(F)(F)F)C2 +CCOc1ccccc1NC(=O)c1nc(C2CCC2)oc1C +CNC(=O)C(C)(C)CNC(=O)CCCc1cc(F)ccc1F +O=S1(=O)N=CN(c2ccc(F)cc2)c2ncccc21 +Cc1nc2cc(NC(=O)C3CCN(C(=O)C(C)(C)C)CC3)ccc2o1 +O=C(CC1C=CCC1)Nc1ccn(CCc2ccccn2)n1 +CCC(C)(C)NC(=O)CS(=O)(=O)c1ccc(O)cc1 +Cn1nc(-c2ccc3c(c2)CCCC3)cc(CO)c1=O +O=C(NCCc1cn2ccccc2n1)NCC1CCCO1 +CCc1nnc(NC(=O)NC2CCCC(C)C2)s1 +COC(=O)c1ccc(C(=O)Nc2cccc3ccccc23)cn1 +N#Cc1ccc(-c2noc(CSc3nnnn3C3CC3)n2)nc1 +COc1ccc(CN2C(C)COCC2C)c(Cl)c1OC +Cc1ccc(CCNC(=O)C2(C)Sc3ccccc3NC2=O)o1 +CCn1c(CCNC(=O)CCc2ccccc2)nc2cccnc21 +CC(C)(C)OC(=O)N1CCNC(c2ccccn2)C1 +Cc1nnnn1-c1cccc(NC(=O)CCC(C)(C)C)c1 +N#Cc1ccc(COCc2cc3cccc4c3n(c2=O)CCC4)cc1 +Cc1cc(CN2CCN(C(=O)Nc3cnccc3C)CC2)on1 +COC(=O)c1c(C)[nH]c(C(=O)N(CCC#N)C(C)C)c1C +CCOc1ccc(OCCC2(C)OCCO2)cc1 +c1csc(-c2cnc(CNCc3ccc4c(c3)OCO4)s2)c1 +O=C(CSc1ccc(F)c(F)c1)OCC1CC(=O)N(C2CC2)C1 +Cc1nc(NC(=O)c2coc(NC(=O)c3cccs3)n2)sc1C +Cn1ccnc1SCC(=O)Nc1nc2ccc(F)cc2s1 +O=C(Nc1cc(-c2ccco2)ccc1F)N1CCC(O)C1 +O=C1COc2cc(NC(=O)c3ccc(Cn4cccn4)cc3)ccc2N1 +COc1cccc2cc(C(=O)NC3CCC(C)CC3)c(=O)oc12 +O=C(c1ccnnc1)N1CCCCc2ccccc21 +COc1c2c(c3c(c1O)c(=O)c1ccccc1n3C)OCO2 +Cc1nc2ccccc2c(=O)n1CC(O)C(F)(F)F +Cc1cc(S(=O)(=O)N2CCCCCC2)cc(N)c1F +N#CC1CCCCC1OC(=O)c1ccc(-n2ccnn2)cc1 +O=C(NC1CC=CCC1)C1CC=CCC1C(=O)NC1CC=CCC1 +CN1C(=O)COc2cc(-c3noc(C(=O)N4CCCCC4)n3)ccc21 +COc1ccc(CNC(=O)c2cc3n(n2)CCCO3)c(OC)c1 +Cc1nc(-c2nnc(NC(=O)Nc3ccccc3Cl)o2)cs1 +CCOc1ccc(OCC(CC#N)N2CCCC2)cc1 +Cc1nc(CN2CCCC3(C2)CN(c2cnccn2)CCO3)cs1 +Cc1ccc(-n2ncc(C(=O)NCCO)c2C2CC2)cc1Cl +Cc1n[nH]c(C)c1CCC(=O)Nc1ccnn1C1CCCCC1 +COCC(=O)N1CCCCC1c1cc2nc(C)c(C)c(O)n2n1 +Nc1cc(Br)ccc1NC(=O)C1CC1 +CC(=O)c1ccc(-c2cccc(-c3ccn(CC(N)=O)n3)c2)s1 +COc1ccccc1OC1CCN(c2nc(N)nc3[nH]cnc23)CC1 +CC(C)C(=O)Nc1cccc(NC(=O)NCc2cccc(C#N)c2)c1 +O=C(NCc1ccco1)c1cc(-c2ccccc2)[nH]n1 +CC(=O)Nc1ncc(S(=O)(=O)Nc2ccc(C)cc2)s1 +CCN(CC)C(=O)C(C)n1nnc(-c2ccccc2)n1 +C=CCN(C(=O)c1cc(C(C)C)nc2c1c(C)nn2C)C1CCCC1 +Cc1cccc(NC(=O)c2c(Br)cnn2C)c1C +O=C1Nc2ccccc2C1C=Cc1ccc2c(c1)OCO2 +CCOc1ccccc1C(=O)NCc1ccc2c(c1)CCN2C(C)=O +Cc1[nH]ccc1C(=O)NCc1cn(-c2ccccc2)nn1 +CCN(CC(C)C#N)C(=O)c1cc2ccccc2oc1=O +CC(=O)N1CCc2cc(NC(=O)NC(C)(C)CO)ccc21 +CN(CC(=O)NC1CC1)C(=O)c1ccc(F)c(N)c1 +CCC1CCCN(C(=O)c2cccc(OC)c2OC)C1 +CCOC(=O)CNC(=O)c1ccccc1SCC#N +COC(=O)c1ccc(C)c(NC(=O)C2CCCC2)c1 +O=C(Nc1cccc(-c2ccsc2)c1)N1CCCC1 +C#Cc1cccc(N(CC(=O)N2CCNC(=O)C2)C(C)C)c1 +NC(=O)C1CN(Cc2cc(F)cc(C(F)(F)F)c2)CCO1 +COC(=O)CN(Cc1ccccc1CC#N)c1ccccc1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)N(C)C(C)CC#N +O=C(Nc1cccc(F)c1F)NC1CCC2(CC1)OCCO2 +CC(Sc1ccccc1)C(=O)Nc1cccc(C#N)c1 +CCOC(=O)CN(C)S(=O)(=O)N1CCCCC1 +O=C(Nc1ccc(S(=O)(=O)NC2CCCC2)cc1)N1CCCC1 +C#CCC(N)c1nc(C(C)C)c(C(=O)OC)s1 +COC(C)(C)CNC(=O)c1cccnc1OCC(F)F +Cc1cc(C)c(S(=O)(=O)Nc2cnn(CC3CC3)c2)cc1C +O=C(NCc1ccccc1F)c1cccc(NC(=O)C2CC2)c1 +CCN(CC(C)(C)O)C(=O)Nc1ccc2c(c1)CCCO2 +Cc1cc2ccccc2n1CCNC(=O)C1CCOC1 +O=C(c1ccc(Cn2cccn2)o1)N1Cc2ccccc2C(O)C1 +COc1cc(NC(=O)NC2CCOCC2)c2ncccc2c1 +COc1ccc2c(c1)OCC(C(=O)NCCc1nncn1C(C)C)C2 +Cc1cc(C)c(C(=O)Nc2nnc(C(C)(C)C)s2)c(=O)[nH]1 +CC(C)COCCNC(=O)c1cc(S(N)(=O)=O)ccc1Cl +O=C(Nc1ncnc2sccc12)c1ccc(Br)cc1 +COC(=O)CSc1nc2ncc(C(F)(F)F)cc2s1 +Cc1noc(CCC(=O)N(C)Cc2ccc(Cl)cc2)n1 +O=C(CCc1ccc(F)c(F)c1)NC1CCCC1 +CCC(C)C(NC(=O)c1cnc(-c2ccccc2)nc1)C(N)=O +CC1(C)CCN(C(=O)Nc2cccn(Cc3ccc(F)cc3)c2=O)C1 +Cc1n[nH]c(C)c1CCC(=O)N(Cc1ccccc1)CC1CCC1 +CCN1CCN(S(=O)(=O)c2ccc(NC(C)=O)c(OC)c2)CC1 +Cc1ccc(NC(=O)CNC(=O)c2ccsc2)cc1C +O=C(Cn1nc2n(c1=O)CCCC2)c1cccs1 +Cc1nc(CC(=O)NC2CCC(C)CC2)cs1 +COc1cc(N2CC(CO)CC2=O)cc(OC)c1OC +COc1ccc2cc(NC(=O)c3cnccn3)cnc2c1 +COc1cc(Cl)c(CNC(=O)c2ccccc2OC)cc1OC +Cc1nc(N)cc(C2CN(Cc3noc(C)n3)CCO2)n1 +COc1ccc(C(=O)OCC(=O)NCc2ccc(Cl)cc2)c(C)c1 +COc1ccc(CN(C)C(=O)C2CCN(S(C)(=O)=O)CC2)cc1 +CCC(=O)N1CCc2cc(C(=O)NC3CCCCC3)ccc21 +CC1CN(C(=O)c2n[nH]c3c2CCCC3)CC(C)O1 +COCCOc1cccc(C(=O)Nc2ccc(F)c(F)c2F)c1 +O=C(Nc1nc(C2CC2)cs1)c1cncc(Br)c1 +O=C(Nc1ccc(-n2cncn2)c(F)c1)C1CCCC1 +O=C(NCC(=O)N1CCCCC1)c1ccnc2ccccc12 +COc1ccc(NC(=O)c2csc(C)n2)c(OC)c1 +CC(=O)NCCNC(=O)NCc1ccccc1Cl +COC(=O)c1sc(NC(=O)Cc2cc(C)ccc2C)nc1C1CC1 +Cc1ccsc1CNC(=O)N1CCC(C(N)=O)CC1 +Cc1onc2c(=O)n(CC#N)nc(-c3ccccc3)c12 +O=C(NCc1noc(C2CCCCC2)n1)c1cccc(F)c1 +FC(F)(F)C(c1ccccn1)n1ccnc1-c1ccccn1 +O=C1CCC(COC(=O)c2ccccc2OCc2ccc(F)cc2)N1 +Cc1ccc(C)c(NCc2nc3n(n2)CCCCC3)c1 +c1cncc(-c2n[nH]cc2CNC2CCc3ccccc3C2)c1 +Cc1ccc(NCc2nnc(C3CCC3)o2)cc1N1CCOC1=O +CC(NC(=O)Nc1cccc(CN2CCCC2=O)c1)c1nccs1 +Cc1cc2ccccc2n1CC(=O)Nc1ccccn1 +COCC(=O)N1CCC2(CC1)NC(=O)c1c(Cl)cccc1N2 +Cc1nc(CCNC(=O)COc2ccc(Cl)c(Cl)c2)cs1 +CCCCN1CCn2c(nc3cc(NC(=O)c4ccco4)ccc32)C1 +COc1ccccc1NC(=O)Cc1noc2ccccc12 +O=C(CCCNC(=O)c1ccsc1)NC1CCCC1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)CCC(C)(C)C +Cc1cc(C(=O)NCC2(C3CC3)CCC2)c(C)s1 +C#CCOc1cccc(COC(=O)C2CCCN(C(=O)C3CC3)C2)c1 +Cc1ccn(-c2ccc(NC(=O)c3cc(-c4ccco4)[nH]n3)cc2)n1 +COCCOC(=O)c1cnn(-c2ccc(Br)cc2)c1C +Cc1cccc(Nc2nccnc2C2CCCN(C(=O)C(C)C)C2)n1 +CC1CCC(CN(C)C(=O)Nc2ccc3c(c2)COC3)CC1 +Cc1ccccc1NC(=O)NCCCN1CCCC1=O +CCc1csc(C2CCCN(C(=O)c3ncoc3CC)C2)n1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2cc(OC)cc(OC)c2)c1C +CCOC(=O)CN(C)c1nccn(C(C)(C)C)c1=O +O=C(CNC(=O)c1cc(Cl)ccn1)Nc1ccc2[nH]c(=O)[nH]c2c1 +COc1cccc(CCNC(=O)CCn2ncc3c(C)cccc32)c1 +CC1(c2ccccc2)CN(CC2=CCCOC2)CCO1 +CC(C)(C)c1nn(CCO)c2c1C(CC#N)CCC2 +CN(C)C(=O)Cn1c(=O)oc2cc(Cl)ccc21 +Cc1ccn(CCNC(=O)c2cc(-c3ccccn3)n[nH]2)n1 +CCCOC(=O)c1cccc(S(=O)(=O)NC2CCCC2)c1 +N#CCCSc1nnc(-c2cc(Cl)ccc2Cl)n1N +CC(C)Oc1ncccc1NC(=O)C(C)NC(N)=O +COCCNC(=O)CC1c2ncccc2C(=O)N1c1cccc(C)c1 +CCc1nnc(COC(=O)c2c(C)noc2N)o1 +Cc1cnc2nc(S(=O)(=O)CC(C)C)sc2c1 +CCCOC1CCCN(C(=O)Nc2ccc(-n3cncn3)cc2)C1 +N#Cc1ccccc1S(=O)(=O)Nc1ccccc1C(=O)NC1CC1 +C=CCNC(=O)c1cc(C(C)C)nc(N2CCOCC2)n1 +CC(C)(C)OC(=O)NCC(=O)NCc1ccoc1 +CN(CCc1ccncc1)C(=O)C(O)c1ccc(Cl)cc1 +COc1ccc2c(c1)S(=O)(=O)N=C(NCc1ccccc1)N2 +CC(NC(=O)Nc1ccc(-c2nnnn2C2CC2)cc1)c1ccccc1 +Cc1nc2c(sc3ncccc32)c(=O)n1CC(=O)NC1CCCC1 +Cc1cc(C)cc(OCCNC(=O)C(C)(C)C#N)c1 +CC(C)NC(=O)NCCOc1ccccc1C(C)C +Clc1ccccc1CNc1ncnc2[nH]cnc12 +Cc1ccc(COC(=O)C23CCC(=O)N2c2ccccc2S3)cc1 +CC(CC(=O)N(C)c1ccccc1S(C)(=O)=O)c1ccc(F)cc1 +Cc1nc(-c2ccc(CNC(=O)NCCc3cccnc3)o2)cs1 +Cc1nc(C)c(C#N)c(SCc2noc(C)n2)n1 +COc1ccc(OCCC(=O)NC2CCCC2)cc1 +O=C(NCCc1cc(Cl)cc(Cl)c1)c1ccco1 +CCc1nc(CN2CCN(C(=O)c3ccc(C(C)C)cc3)CC2)n[nH]1 +CN(C(=O)COCC(F)(F)F)c1ccccc1S(C)(=O)=O +COc1ccc(-c2noc(-c3ccc[nH]c3=O)n2)cc1OC +CC(=O)NC(C)C(=O)N(C)Cc1ccc(Cl)cc1 +O=C1COc2c(cccc2C(=O)Nc2ccc3sccc3c2)N1 +CC(c1ccccn1)N(C)S(=O)(=O)c1ccccc1 +O=C(COc1ccc(F)cc1)N1CCOC(c2ccccc2)C1 +CCOc1cc(C2NC(=O)c3cccc(C)c3N2)ccc1O +CCCCNC(=O)n1c(=O)oc2ccc(Cl)cc21 +CC(=O)Nc1ccc(F)c(C(=O)OCc2ccc(F)cc2)c1 +N#Cc1ccc(CNC(=O)NC2CCSc3c(F)cccc32)cc1 +O=C(CSc1nc2ccccc2o1)Nc1cn[nH]c1 +C=CCN(Cc1ccccc1)C(=O)Nc1ccc2c(c1)COC2 +CN(CC(=O)NC(C)(C)C)C(=O)Nc1cccc(Cl)c1 +Cc1cc(Cl)ccc1NC(=O)N(CCC#N)CCC(F)(F)F +NC(=O)CCCNC(=O)Cn1ccc(=O)[nH]c1=O +CNC(=O)C(C)Nc1ccc(N)c(C(F)(F)F)c1 +CN(C)C(=O)NC1C2CN(S(=O)(=O)c3cccs3)CC21 +NC(=O)c1ccccc1NC(=O)c1cncc(Br)c1 +O=C(CCSc1ccccc1)N1CCCCCC1 +CN(CC1CCC1)C(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +COCCCNC(=O)c1cc(-c2cccc(OC)c2)[nH]n1 +Nc1oc2ccc(O)cc2c1C(=O)c1ccc(F)c(F)c1 +CCOc1ccc(Br)cc1-n1cnnn1 +COc1ccc(NC(=O)CCCCO)cc1Cl +C=CCCOCC(=O)N1CCC(c2nnc3n2CCC3)CC1 +COc1cccc(CNC(=O)COc2cccc(C(F)(F)F)c2)c1 +CC(C(=O)N1CCOCC1)n1c(N)nnc1SCc1ccccc1 +COc1ccc(OCCNC(=O)CC2CC3CCC2C3)cc1 +CCCc1nn(CC(=O)N(C)C)c(=O)c2cc3ccsc3n12 +O=C(CC(F)(F)F)N1CCC(C2CCN(c3ncccn3)CC2)C1 +CC1CCCN(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)CC1 +N#CCn1c(=O)n(Cc2ccccc2Cl)c(=O)c2cccnc21 +N#Cc1cccnc1NCC1CCN(c2ncnc3sccc23)C1 +COC(=O)Nc1ccc(OCC(=O)N(c2ccccc2)C(C)C)cc1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)N(C)Cc1cccs1 +CC(=O)Nc1c(-c2ccccc2)nc2ncc(C)cn12 +COc1ccc(CCC(=O)NCCc2ccncc2)cc1 +O=C(Cc1cn2ccsc2n1)Nc1cccc2c1CCCC2 +C=CCC1CC=CC(C)N1C(=O)c1n[nH]c2ccccc12 +CCOC(=O)Nc1nnc(Sc2ccc(C#N)cn2)s1 +COc1ccccc1N1CC(C(=O)NC(C)(C)CC(C)(C)C)CC1=O +CCC1c2ccsc2CCN1C(=O)CN1C(C)COCC1C +COC(=O)c1cc(Cn2nnc3ccccc3c2=O)c(C)s1 +COc1cc(-c2noc(-c3ccc(OCC(F)F)nc3)n2)ccn1 +N#CC1(NC(=O)CSc2nc3sccc3c(=O)[nH]2)CCCC1 +CC(C)(C)NC(=O)CCC(O)c1ccc2c(c1)OCCO2 +Cc1ccc(C(=O)c2cccc(C(F)(F)F)c2)cn1 +COc1ccc(C#N)cc1Cn1cnc2sc(C)cc2c1=O +COC(=O)c1nnn(-c2cc(Cl)cc(Cl)c2)c1N +Cc1ccc(CN(C)C(=O)c2c(C)oc(C)c2S(N)(=O)=O)o1 +O=C(Cc1ccc(F)cc1)N1CCCCC1CO +COc1ccc(-c2nnc(NC(=O)c3cccc(C)c3)o2)c(OC)c1 +OCC(CC(CO)c1ccncc1)c1ccncc1 +Cc1ccc(C)c(OC(=O)CN(C)S(C)(=O)=O)c1C +Cc1cc(C(=O)Nc2ncc(C(N)=O)s2)c(C)o1 +NS(=O)(=O)c1ccc(Br)c(Cl)c1 +CC1(C(N)=O)CN(C(=O)C2(c3ccccc3)CCCC2)CCO1 +NC(=O)c1ccccc1OCCn1cnc2ccccc2c1=O +Cc1nc(-n2nnc(CO)c2C(C)(C)C)sc1C +COc1ccc(C(C)(O)c2cccc(OC)c2)cc1 +CCCc1noc(CN(C)C2CS(=O)(=O)c3ccccc32)n1 +Cc1cc(C)n2ncc(C(=O)NCCC3=CCCCC3)c2n1 +CCc1c(C)sc2nc(-c3ccoc3)[nH]c(=O)c12 +Cc1cc(C(=O)NC(C)c2ccccc2Br)c(C)o1 +Cn1ccc(NC(=O)NCc2ccc(N3CCCC3=O)cc2)n1 +CNC(=O)c1ccc(Cl)c(NC(=O)c2cnccn2)c1 +Cc1nn(-c2cccc(C(F)(F)F)c2)c(C)c1CC(=O)N1CCC1 +Cc1cc(NC(=O)N2CCOCC2C2CC2)ccc1-n1cnnn1 +CCCc1nnc(NC(=O)c2cc(-c3ccc(C)cc3O)[nH]n2)s1 +COC(=O)c1cccc(OCC(=O)N(C)C2(C#N)CCCCC2)c1 +COc1ccc2cc(C(=O)NCCc3ccccn3)c(C)nc2c1 +Nc1cc(C(=O)NCC2CCCCO2)ccc1F +O=C(NCc1nnnn1-c1ccccc1)Nc1ccc2c(c1)OCO2 +COCCOc1ncccc1C(=O)Nc1cc(Cl)ccc1Cl +N#Cc1ccc(NC(=O)c2noc3c2CCc2ccccc2-3)cc1 +Cc1noc(C)c1C(=O)Nc1ccccc1C(=O)NCC1CCCO1 +Cc1nc(NCC2=CCCCC2)c2cnn(C)c2n1 +COc1ccccc1NC(=O)CCc1ccccn1 +CN1C(=O)c2cc(Cl)ccc2NC1c1cc(F)ccc1F +Cc1cn2c(CN(C)C(=O)CNC(=O)C3CCCC3)c(C)nc2s1 +CC(=O)c1ccc(S(=O)(=O)N2CCCC2c2cccn2C)cc1 +Cc1ccccc1NC(=O)COC(=O)c1cc(Br)c[nH]1 +NC(=O)c1csc(CNc2cnn(-c3ccccc3F)c2)c1 +O=C(CSc1ccc(Br)cc1)NC1CC1 +CCC(=O)Nc1cccc(NC(=O)NCc2ncc[nH]2)c1 +COc1ccc(CCSc2nnc(-c3ccco3)n2C)cc1 +Cc1ccc(-c2n[nH]c(SCC(=O)Nc3cc(C)no3)n2)cc1 +CCCOc1ccccc1NC(=O)CNC(=O)c1cccc(F)c1 +Cc1ncsc1COC(=O)Cc1cccc2cccnc12 +CC(C)Oc1ccccc1-c1cc(N)c(=O)n(C)n1 +CS(=O)(=O)NC1CCCN(C(=O)Cc2cn3ccccc3n2)C1 +CC(C)(CCC(=O)NCc1csc(=O)[nH]1)c1ccccc1 +COc1cccc2sc(NC(=O)c3cnc4ccccc4n3)nc12 +CN(C)C(C(N)=O)c1ccccc1Br +Cc1ccc(C(C)NC(=O)Nc2cccc(F)c2F)o1 +CCC(=O)NC1CCCN(C(=O)NCCCC(C)(C)CO)C1 +Brc1ccccc1-c1nc(-c2nc[nH]n2)no1 +CCN(CC1CC1)C(=O)CNS(=O)(=O)c1cn(C)cn1 +Nc1ccc2c(c1)S(=O)(=O)c1cc(N)ccc1O2 +CCC1CCCCN1C(=O)c1ccc(-n2cncn2)cc1 +CC(C)Oc1ccc(NC(=O)NCc2cnn(C)c2)c(F)c1 +CC(C)OC(=O)c1cc(-c2ccc3c(c2)OCCO3)on1 +Cc1ccc(C)c(C(=O)NCc2ccc3[nH]c(=O)[nH]c3c2)c1 +Cc1c(C)n(-c2ccc(O)cc2)c2ncnc(N)c12 +O=S(=O)(Cc1nc(-c2ccsc2)no1)c1ccc(Cl)cc1 +CC(C)c1nnc(SCCn2c(=O)oc3ccccc32)n1C1CC1 +Cc1ccc(C(n2nc(C)cc2C)n2nc(C)cc2C)cc1 +O=C(COC(=O)c1ccc(Cl)cc1F)NCC1CCCO1 +Cn1c(CNC(=O)Nc2nccs2)nnc1C1CC1 +CCCNC(=O)N1CCN(c2ccccc2OC)C(=O)C1C +CCOC1COCC1NC(=O)CCCc1ccc(Cl)cc1 +O=S(=O)(Cc1c(F)cccc1Cl)N1CCc2[nH]cnc2C1 +CC(C)C(Sc1nnnn1C1CC1)C(=O)N1CCOCC1 +CCCn1cc(NC(C)C(=O)N(C)C(C)C)cn1 +Cc1nsc(N2CCN(C(=O)c3ccc4cc[nH]c4c3)CC2)n1 +CC(C)c1cc(N2CCOC(C(F)(F)F)C2)n2nccc2n1 +NC(=O)CCN(Cc1ccccc1)C(=O)c1ccc(C(N)=O)nc1 +Cc1ccc2c(CN3CCC(O)(C(F)(F)F)CC3)cc(=O)oc2c1 +O=C(NCc1ccccc1Cl)C1(c2ccccc2)CCOCC1 +CCc1cc(C(=O)Nc2nnc(Cc3cccc(F)c3)s2)on1 +CCc1cc(C(=O)NC2CCN(C(=O)OC)CC2)sc1C +O=C(CCn1cccn1)NCC1(c2cccc(Cl)c2)CCCC1 +CC(C)CNC(=O)CNC(=O)Nc1ccc(C(=O)NC(C)(C)C)cc1 +COc1cc(Br)c(OC)c(C(=O)NCC2CCCO2)c1 +COc1ccc(CNCC(c2ccc(F)cc2)N(C)C)cc1F +CC12CCC(C(=O)OC3CCCCC3)(OC1=O)C2(C)C +c1cnc2ccc(NCCc3nccs3)cc2c1 +Cc1ccccc1OCCCn1cccc(C)c1=O +C#CCN1C(=O)C2(CCCC2)Nc2cc(C)c(C)cc21 +COc1ccncc1NCc1ccc2c(c1)OCCO2 +NC(=O)c1ccccc1NC(=O)c1ccc(OCC(F)F)nc1 +CN(Cc1ccco1)C(=O)CC1CCN(C(=O)c2ccccc2)CC1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)Nc1ccc(F)cc1 +COc1ccc2c(Cl)c(C(=O)N(C)C)sc2c1 +C#CCSc1nncn1NC(=O)Nc1ccc(Cl)cc1 +COCCCNC(=O)c1ccc(-c2cc(N3CCCC3)ncn2)cc1 +Cn1cc(C(=O)N2CCCc3ccc(N)cc32)cn1 +CCc1nc(CC(=O)NC2CCC(O)CC2)cs1 +O=C(CC1CCCN1C(=O)c1ccc(F)cc1Cl)c1ccccc1 +CCC1=C(C(=O)OC)C(c2ccc(C)o2)NC(=O)N1CC +CCS(=O)(=O)N1CCCC1C(=O)c1c(C)cc(C)cc1C +O=C(Cn1cncn1)NC1CCN(c2ccccc2)CC1 +Cc1cc(C)n(CC2CN(CC(O)Cn3cccn3)CCO2)n1 +Cc1ccoc1C(=O)NC1CCN(c2ccc(C#N)cn2)CC1 +COc1ccc(-c2cc(CC(=O)N3CCC(C)CC3)no2)cc1 +O=C(NCCCc1nc2ccccc2[nH]1)c1cccs1 +C=CCn1c(=O)oc2ccc(C(=O)Nc3cccnc3)cc21 +N#Cc1ccccc1OCC(=O)N1CCCCCC1 +Nc1ccc2ccnc(C(=O)NCc3ccccn3)c2c1 +C=CCNC(=O)CCc1ccc(S(=O)(=O)N2CCOCC2)cc1 +COc1cc(N)c(C(=O)OCC2CC2)cc1OC +COc1ccccc1SCC(=O)Nc1nccs1 +NC(=O)c1cccc(OC(=O)C2(c3ccccc3)CCC2)c1 +CNc1ncc(Br)cc1S(=O)(=O)NCC1CC1 +COc1ccccc1NC(=O)NCC(C)N1CCc2ccccc21 +O=C(NCCCc1nc2ccccc2s1)NCC(=O)N1CCCC1 +COc1ccc(NC(=O)COc2ccc(Cl)cc2C)cc1OC +Cc1nccn1-c1cc(C(=O)N(CC2CC2)C2CCCCC2)ccn1 +Cn1cccc1C(O)CNC(=O)c1ccc2ccccc2c1 +COC(=O)c1ccc(N(C2CC2)C(F)(F)F)cc1 +Cc1cccc(C)c1-n1ccn(CC#N)c(=O)c1=O +C#CCOC(=O)c1c(S(N)(=O)=O)c(C)nn1C +O=C(NCc1ccc2c(c1)OCO2)c1ccc(-c2ccccc2)[nH]c1=O +Cc1nscc1C(=O)NCCn1cnc2ccccc21 +Cc1ccc(N)c(S(=O)(=O)NCC2CCC2)c1C +Cc1cncc(C(=O)NC2Cc3ccccc3C2)c1 +COc1cc(OC)cc(-n2nnnc2SCC(N)=O)c1 +CCC(=O)Nc1sc2c(c1C(=O)N1CCCCC1)CCCCC2 +COC(=O)CNC(=O)c1ccc(-c2ccc(C)c(Cl)c2)o1 +CC1CN(C(=O)CN(C)c2ccc(F)c(F)c2)CC(C)O1 +Cc1cc(C(C)NC(=O)NCC2CN3CCCCC3CO2)c(C)o1 +FC(F)(F)c1ccc2c(c1)CCNC2c1cncnc1 +Cc1cc(C)cc(OC(=O)Cn2nc3ccccn3c2=O)c1 +CCCCC(NC(=O)c1cscn1)c1ccc(OC)cc1 +CCC(=O)N1CCCN(C(=O)Nc2cccc(Cl)c2OC)CC1 +COC(=O)C1CC(O)CN1Cc1sccc1C +CC(=O)c1ccc(NC(=O)NC(C)COC2CCOC2)cc1C +O=C(CNC(=O)c1cccnc1)NCC(F)(F)F +CN(C(=O)C(C)(C)c1ccc(N)cc1)c1ccccc1 +Cc1cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)ccc1F +Cc1cc(=O)n2nc(CN(Cc3ccc(F)cc3)C3CC3)sc2n1 +Cc1cccc(C(C(=O)NCc2cn3cccnc3n2)N(C)C)c1 +COC(=O)c1cccc(NC(=O)COc2ccc(C)cc2OC)c1 +CCn1nc(C)c(NC(=O)C2CC(=O)OC23CCCCC3)c1C +O=C(C1CCC(F)(F)CC1)N1CCCC(c2cnccn2)C1 +CNC(=O)c1cccc(CCNC(=O)NCc2cscn2)c1 +CCCCS(=O)(=O)N1CCC2C1CCN2Cc1cnn(C)c1 +CCCNC(=O)CNS(=O)(=O)c1ccc(NC(C)=O)cc1 +Cc1nc(CS(=O)(=O)c2ncc(-c3ccccc3)n2C)cs1 +Cc1cccc(NC(=O)CN(C)C(=O)c2cccc(C#N)c2)c1C +CC(C)CC(C)OCCC(=O)N1CCN(c2nccs2)CC1 +CC(C)CCN(C)S(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +Fc1ccc(CN2CCc3nc(N4CCCC4)ncc3C2)cc1F +CCC(C)n1ncc(C(=O)Nc2c[nH]c(=O)c(C)c2)c1C1CC1 +O=C1CC(c2cccs2)c2cnn(-c3ccc(F)cc3)c2N1 +CN(CC(=O)NC(C)(C)C)C(=O)c1c[nH]c2cccc(F)c12 +CC(C)(C)C(=O)N1CCCC1C(=O)N1CCNCC1 +COC(=O)C(NC(=O)c1cnn(-c2ccccc2)c1)C(C)C +Cc1cccc(C(N)=O)c1NCC(=O)Nc1c(C)nn(C)c1C +CC(NC(=O)Cc1ccsc1)c1ccc(-n2ccnc2)cc1 +CCC1CCC(NC(=O)c2cccc(N3CCOC3=O)c2)CC1 +Cc1ccc(NCC(=O)Nc2c(C)nn(C)c2C)cc1Cl +CCCN1CCN(C(=O)Cn2cccc2C(=O)c2ccccc2)CC1 +Cc1cccc2c(CC(=O)NCC3Cc4ccccc4O3)c[nH]c12 +Cc1ccc(OCCN(C)C(=O)CCc2c(C)n[nH]c2C)cc1 +C1=C(c2cccs2)CCN(Cc2cnc3cnccn23)C1 +N#Cc1cccc(N2C(=O)CNc3cccc(Cl)c32)c1 +COc1ccccc1CC(=O)N1CCN(C(=O)c2ccoc2)CC1 +Cc1ccc(S(=O)(=O)Cc2ccc(C(=O)NCC3CC3)cc2)cc1 +CCN(CCC#N)C(=O)CNc1ccccc1-n1cccn1 +CN(CCOCC1CC1)c1nc(N)nc2[nH]cnc12 +CNC(=O)CN1C(=O)CCC12CCCN(c1cc(OC)ncn1)C2 +CN1CCOC(C(=O)Nc2cc(-c3ccccc3)on2)C1 +O=C(Nc1ccccc1F)c1c[nH]c2c(F)cccc2c1=O +COc1ncccc1C1CC(=O)NCc2nc3ccccn3c21 +CCCc1c(C(=O)Nc2nccs2)nnn1-c1cccc(Cl)c1 +CCCn1nc(C)c(C(=O)OCc2ccoc2)c1C +Cc1ccc(C)c(S(=O)(=O)N(CCC#N)CCC(F)(F)F)c1 +Cc1ccc(NC(=O)CSc2nccc(=O)[nH]2)cc1 +Cc1ccccc1C(=O)NCC(c1ccccc1)N1CCOCC1 +CC(=O)NC1C(O)OC2COC(C)(C)OC2C1OC(C)=O +COc1ccc(OC)c(C2=NCC(=O)Nc3c2oc2ccccc32)c1 +N#Cc1ccccc1Cn1ccc2occc2c1=O +CCCNC(=O)C(C)Cn1cc(Br)cn1 +CC1CCCCN1C(=O)Nc1noc2c1COc1ccccc1-2 +CC(=O)Nc1ccccc1OCC(=O)Nc1ccc(C#N)cc1 +CCN(CC)S(=O)(=O)c1cc(NC(=O)C2CC=CC2)ccc1C +CCOc1ccccc1C(=O)NCc1ccc2c(c1)OCO2 +COC(=O)CN(C(=O)c1sc(-c2ccccn2)nc1C)C(C)C +Cc1noc(C)c1CC(=O)NCc1cccc(COC(C)C)c1 +N#Cc1nc(C2CC2)oc1N1CCN(c2cnc3ccccc3n2)CC1 +COc1ccc(C(=O)N2CCC(Oc3ncccn3)CC2)cc1OC +CC(C)(C)c1nnc(NC(=O)NCC(=O)NCc2ccco2)s1 +O=C(Cc1c[nH]c2ccc(F)cc12)NCCC(=O)Nc1ccncc1 +COc1ccc2c(c1)OCC(CNc1nccnc1OC)C2 +CNC(=O)c1ccc(OC)c(NCc2cccc(C)c2)c1 +Cn1ncc(Cl)c1C(=O)NC1C2CC3CC(C2)CC1C3 +Cc1cc(C)n(-c2cncc(N3CCC4(CC3)OCC(C)O4)n2)n1 +Cn1c(=O)c2ccccc2n(CC(=O)NCC2CCCO2)c1=O +COC(=O)c1nc2ccccc2nc1NCc1cccs1 +COc1c(Cl)cccc1NC(=O)c1cncc(Br)c1 +Cc1ncc(C(=O)N(CC2CC2)c2cccnc2)s1 +O=S1(=O)N=C(Nc2ccc(Cc3ccncc3)cc2)c2ccccc21 +c1cncc(CN2CCCC2c2ccnc(Nc3cnccn3)n2)c1 +Cc1cccc(CCNCc2cccc(C(N)=O)c2)c1 +COc1ccc2c(c1)CCCC2CC(=O)NCC1CC1 +CCCc1nn(-c2ccccc2)c2cc(C)[nH]c(=O)c12 +c1ccc2ncc(NCCN3CCOCC3)cc2c1 +Cc1ccnc(-c2cccc(NC(=O)c3cccc(F)c3)c2)n1 +COc1ccc(-c2cc(C(=O)NCc3ccncc3)sc2C)cc1 +CCCNc1nnc(-c2cccn(C(C)C)c2=O)s1 +Cn1ccnc1C(=O)C1CCCN(C(=O)CCCn2cnnn2)C1 +Cc1noc(C)c1C(=O)Nc1cccc(Oc2cnccn2)c1 +Cc1cccc(=O)n1CCCCNC(=O)c1cc(F)ccc1O +Cc1ccc(C(NC(=O)c2ccc(=O)n(C)n2)c2ccccc2)cc1C +CCC(C(=O)NCCC(O)C1CC1)c1ccccc1 +Cn1cc(C(=O)Nc2cnc(-c3ccccc3)nc2)c(C(F)(F)F)n1 +CCc1onc(C)c1NC(=O)C1(c2cccc(Br)c2)CC1 +O=C(COC(=O)c1ccco1)Nc1nc2ccccc2s1 +Cn1nc(CO)c2c1CCN(C(=O)c1cc(-c3cccs3)n[nH]1)C2 +O=C(NCCNC(=O)N1CCc2c(F)cc(F)cc2C1)c1ccn[nH]1 +CCn1nnnc1COc1cccc(C(=O)N2CCOCC2)c1 +COc1cccc(CN(C)C(=O)CNc2ccc(F)c(Cl)c2)c1 +O=C(NCc1cc(Br)cs1)C1CCOC1 +CC(Sc1ccc(Cl)cc1)C(=O)NCc1cscn1 +CN(CC(=O)NC1CC1)S(=O)(=O)c1cnn(C)c1 +Cn1nc(C(=O)Nc2ccccc2N2CCCC2)c2ccccc2c1=O +Cc1ccccc1C(=O)NCC(O)(c1cccs1)C1CC1 +CCCCn1nccc1NC(=O)c1ccc(C)c(NC(C)=O)c1 +Cc1nn(C(=O)C2CC(=O)N(Cc3ccccc3)C2)c(C)c1C(C)C +CCOCC(=O)NCCn1ncc2c1c(C)nn2C +CCn1cc(C(=O)NC(C)C(C)N2CCOCC2)c(C(C)C)n1 +COC(C)(C)c1noc(Cc2csc(NC(=O)C(C)C)n2)n1 +CC(=O)Nc1ccc(C(=O)N2CC(c3nc4ccccc4[nH]3)C2)cc1 +COc1cc(C#N)ccc1OC(=O)CSc1ccc(Cl)cc1 +COc1cc2c(c(Cl)c1OC)C(c1ccoc1)NCC2 +O=C(NC1CCCCC1)c1nc[nH]c1C(=O)NC1CC1 +N#Cc1ccc(OCC(=O)NCCN2CCOCC2)cc1 +O=C(CCc1ccsc1)N1CCC2(CC1)OCCCC2O +Cc1ccc2nc(CNC(=O)C3(c4ccc(F)cc4)CC3)cn2c1 +CC(C)(C)NC(=O)COc1ccc(Cl)cc1C(N)=O +CC(=O)c1cccc(NC(=O)C(C)N2c3ccccc3CC2C)c1 +COCCn1nc(C)c(CNC(=O)C(C)c2ccsc2)c1C +COc1cccc(CN2CCOC(C)(c3cnn(C)c3)C2)c1OC +CC(=O)c1nnn(-c2ccc(F)cc2)c1NCCCn1ccnc1 +Cc1cc(NC(=O)c2ccc3oc(=O)n(Cc4ccccc4)c3c2)no1 +COc1ccc(C(=O)NC(c2ccccc2)c2ccccc2)cn1 +Cc1ccc(C(C)NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +CC(C)C(Sc1ncnc2ccsc12)C(=O)NCc1ccco1 +Cc1n[nH]c(C)c1S(=O)(=O)Nc1cccc(N)c1 +CCNC(=O)c1cc(C)c(C)c(S(=O)(=O)N(C)C)c1 +CC(=O)Nc1ccc(C)c(NC(=O)NC(C)c2ccccc2)c1 +CC1=NC(=O)C(CCC(=O)Nc2ccc(C)c(Cl)c2)C(C)=N1 +CC1CCC(N(C)C(=O)CS(=O)(=O)c2ccccc2F)CC1 +CCCOc1ccc(NC(=O)c2sc(C)nc2C)c(C)c1 +Cc1cc(Cl)ccc1OCC(=O)N1CCC(=O)CC1 +O=C(COc1ccc(CO)cc1)N1CCC(Cc2ccccc2)CC1 +Cc1c(C(=O)OCc2ccccc2F)cnn1-c1ccncc1 +Cc1ccc(-c2cc(N)c(=O)n(CC(=O)N3CCC(C)CC3)n2)s1 +CC(=O)N1CCc2cc(NCc3ccccc3)ccc21 +CCC1CCc2nc(NC(=O)CNC(=O)NC)sc2C1 +CCc1ccc(-c2nc3c(cnn3Cc3cccs3)[nH]2)nc1 +O=C(OCc1nnc(-c2cccs2)o1)c1ccc2ncsc2c1 +CC(O)c1nc2cc3c(cc2n1CC#N)OCCO3 +O=C(Cc1cccs1)Nc1cccc(C#CCO)n1 +O=c1[nH]c(CN2CCCCC2CCO)nc2ccccc12 +Cc1cccn2c(=O)c3cc(C(=O)NCc4cccnc4)n(C)c3nc12 +Cc1cc(C(O)CCNC(=O)C2CC=CCC2)c(C)o1 +COCCN(CC(C)C)C(=O)Nc1ccc2c(c1)COC2 +N#Cc1ccc(S(=O)(=O)N2C(C(N)=O)CC3CCCCC32)cc1 +COC(=O)CC(C(=O)OC)c1cccc(Cl)c1 +O=S(=O)(CCc1ccccc1)N1CCN(c2cccc(O)c2)CC1 +Cc1ccccc1-n1c(C)nnc1SCC(=O)c1ccccc1 +CCOc1ccc(C(=O)NC(CC(C)C)C(=O)NC)cc1 +O=C(NC1CCCc2ccccc21)c1ccncc1 +CCN(CC(C)C#N)C(=O)CSc1nncn1-c1ccccc1C +CC(=O)c1cccc(OCc2cn3ccccc3n2)c1 +Nc1cc(N)nc(SCC(=O)Nc2ccc(Cl)cc2Cl)n1 +COCC(O)CN(C)S(=O)(=O)c1c(C)n[nH]c1C +COc1ccc(NC(C)=O)cc1NC(=O)c1c[nH]c2cccc(F)c12 +O=C(c1cccnc1)c1cccc(C2OCCCO2)c1 +CC(C)CC(C)OCCC(=O)NC1CCC(=O)NC1 +Cc1nnc(Cn2ncc(N3CCCCC3)cc2=O)s1 +CC(C)(C)NS(=O)(=O)c1cc(NC(N)=O)ccc1F +COCCN1CCN(C(=O)NCc2cnn(C)c2C)CC1=O +CC(C)c1cc(C(=O)NCc2nnc3ccccn23)c2ccccc2n1 +COCCN1C(=O)CCC12CCC(NC(=O)c1cccs1)CC2 +COC(=O)CNc1ccccc1NC(=O)c1ccc(Cl)cc1 +O=C(CSc1nnns1)c1ccc(F)cc1 +CC(C)(C)OC(=O)N1CCCC(CNc2ccc3nncn3n2)C1 +Cc1nc(C(C)C)c(C(=O)Nc2cccc3ncccc23)s1 +COc1cc2c(cc1OC)C(=O)N(CCO)CC2 +Cc1ccc2ncc(C(=O)NCCNC(=O)CC3CCCC3)n2c1 +Cn1c(=O)oc2cc(NC(=O)c3c[nH]c4cccc(F)c34)ccc21 +CC(=O)c1c2c(nn(CCC(C)C)c1=O)CCCC2 +Cc1noc(C)c1C(C)NS(=O)(=O)c1cc(F)ccc1Cl +CN1CCN(C(=O)NC2CC(=O)N(C3CC3)C2)Cc2ccccc21 +CC(=O)Nc1nc2ccc(NC(=O)c3ccc(C)cc3)cc2s1 +Cc1cnn(C2CCCN(C(=O)C3CC3c3ccc(C)s3)C2)c1 +CC(C)(C)OC(=O)N1CC2CCC2(NC(=O)OCc2ccccc2)C1 +CCC(OC)C(=O)N(c1ccc(C#N)cc1C)C1CC1 +CC(=O)Nc1ccccc1OCC(=O)NCC1(c2ccccc2)CC1 +CCOC(=O)CN(CC)C(=O)c1n[nH]c2ccccc12 +CCOc1ccc(CC(=O)N2CCCc3c(cnn3C)C2)cc1 +COc1ccc(F)cc1NC(=O)CCCc1nc(C(C)C)no1 +COC(=O)c1ccc(N2CCN(C(=O)c3ccc[nH]3)C(C)C2)cc1 +Cc1ccc(NC(=O)C2(O)CCCC2)cc1N1CCOC1=O +CC(=O)N(C)CC(=O)N=c1[nH]c2ccccc2n1C1CCCC1 +CCOc1cccc(CNc2nccc(-n3nc(C)cc3C)n2)c1 +Cn1cc(CCC(=O)N2CCCC2c2cccc(F)c2)cn1 +O=C(NCC1(Cc2ccccc2)CCC1)c1cnns1 +CN(C)C(=O)CNC(=O)c1ccc(Br)c(F)c1 +CCN(CC)S(=O)(=O)CCNC(=O)N1CC(C)OC(C)C1 +COc1ccc(S(=O)(=O)NC(C)CO)cc1C +CC1CC1C(=O)N(c1cccc(O)c1)S(C)(=O)=O +O=C(Nc1nc(C2CC2)cs1)c1cccc(Oc2ccccn2)c1 +O=C(Nc1ccc(Cl)cn1)C1CCCN(C(=O)Cc2ccc[nH]2)C1 +CNC(=O)C1CCC2(CCN(c3ncccn3)CC2)CO1 +COc1ccc(-c2ccc3nc(N)nn3c2)c(F)c1 +Cc1cccc(C)c1NC(=O)C1CCCN(S(C)(=O)=O)C1 +Cc1cccc(-n2nnnc2SCC(=O)c2cc(C)n(C)c2C)c1 +c1ccc2c(c1)CCCN2Cc1nnnn1C1CCCCC1 +Cc1cc(-c2nnc3sc(-c4cccc(F)c4)nn23)[nH]n1 +CC(C)c1ccc(C(=O)N2CCCCCC2)c(N)n1 +Cn1cc(CC2C(N3CCOCC3)CCN2Cc2cnn(C)c2)cn1 +Fc1ccc(-c2nc(CN3CCCC4(C3)OCCO4)cs2)cc1 +COc1ccccc1NC(=O)NCC#CCOc1cccnc1 +COc1ccc(SCCn2c(=O)oc3cccnc32)cc1 +Cc1ccc(C(=O)NCc2ccccc2OCCC(C)C)cn1 +CCCC1CN(C(=O)Nc2ccc(-c3csnn3)cc2)CCO1 +COc1ccccc1-c1ccc(CC2CCN(C(C)=O)CC2)cn1 +O=C(c1cnccn1)N1CCC2(CC1)CC(Oc1cccnc1)CO2 +CC(C)NC(=O)Nc1ccc(NC(=O)COc2ccccc2F)cc1 +O=C(NCc1ccccn1)NC1CCOc2c(Cl)cccc21 +Cc1ccc(C(O)CCC(=O)NCc2ccncc2)c(C)c1 +CC(C)NC(=O)COc1ccc(NC(=O)c2cnn(C)c2)cc1 +CCc1nnnn1Cc1nc(-c2cccs2)no1 +CNC(=O)CSc1nnc(-c2ccc(Cl)cc2)n1N +CCOC(=O)CN(C(C)C)S(=O)(=O)c1cccc(C#N)c1 +Cc1ccc(-n2ccc(=O)c(-c3nc(-c4ccccc4F)no3)n2)cc1 +CCN(C(=O)Cn1cc(Br)ccc1=O)c1ccccc1 +Cc1c(C(=O)NCCc2cccnc2)cnn1-c1ccncc1 +CCOc1ccc(C2CC(=O)Nc3c2cnn3C(C)(C)C)cc1 +O=C(OCc1ccccc1)N1CCC(N2CCCNC2=O)CC1 +CCCSc1c(CCC)cnc2c1c(=O)n(C)c(=O)n2C +CC(C)Oc1ccc(CNC(=O)NCC(C)(O)c2ccsc2)cn1 +CCCc1nc2ccccc2n1CC(=O)Nc1cccc(OC)c1 +COC(=O)C(C)CN(C)C(=O)Cc1ccc(O)cc1 +CCN1C(=O)C2(NC(=O)c3ccc(Cl)cc3N2)c2cc(C)ccc21 +O=C(NC(CN1CCCC1=O)c1ccccc1)c1cccnc1 +Cc1c(N)ccc2c1S(=O)(=O)c1c-2ccc(N)c1C +CCCCCC(=O)Nc1ccccc1N1CCCC1=O +O=c1c2ccc(F)cc2ncn1CCc1ccncc1 +Cc1cnn(C2CCCN(C(=O)c3ccc(N(C)C)nn3)C2)c1 +O=C(CC1C=CCC1)Nc1ccc(-n2cnnn2)cc1 +COC(=O)NCC(=O)NC1CCCC1Cc1ccccc1 +N#CCOc1ccc(CC(=O)N2CCc3ccc(Cl)cc3C2)cc1 +CC1(C(=O)NCCCN2CCOCC2)Oc2ccccc2NC1=O +Cc1nc(CSc2nnc(C)n2N)nc2ccccc12 +O=C(OCc1nnc(-c2ccccc2)o1)C1CCCC1 +COc1ccc(-c2cn3c(C)c(C)sc3n2)cc1 +Cc1cnc(C(=O)NC(C)c2ccccc2Cl)cn1 +CC(=O)c1cccc(OCC(=O)Nc2cccc(-c3nc[nH]n3)c2)c1 +CCCS(=O)(=O)NCCC(=O)N1CCN(c2ccccc2)CC1 +CCC(C)NC(=O)c1cc2cccc(OC)c2oc1=O +CC(Nc1cc(-c2ccccc2F)nc2ccnn12)c1cnccn1 +CC1CCc2cccc(OCCN3CCOCC3)c2N1 +CCOc1ccc(-c2noc(COc3ccccn3)n2)cc1 +Brc1ccccc1CCc1ncccn1 +O=C(c1ccc(F)cc1)C1CCCN(C(=O)c2cc(C3CC3)[nH]n2)C1 +CCCN(Cc1ccccc1)C(=O)CNC(=O)c1cccc(F)c1 +CCn1nnc2cc(C(=O)N(C)C3CCc4ccccc4C3)ccc21 +Nc1ccccc1-c1nc(-c2ccc3[nH]c(=O)[nH]c3c2)cs1 +Fc1ccc(-n2cc(-c3ccnc(N4CCCCC4)n3)cn2)cc1 +CS(=O)(=O)N1CCN(C(=O)C2CCCN(C(N)=O)C2)CC1 +Nc1ccccc1Cc1nccn1CC1CCCO1 +CC(C)CNC(=O)C(NC(=O)c1ccccc1)C(C)C +CC(C)c1cc(C(=O)N2CCCC2)nc(N2CCCCC2)n1 +COC(=O)c1ccc(CN(CCO)c2ccccc2)cc1 +Cc1ccc2c(c1)NCCN2CC(=O)N1CCC(C)CC1 +CC(C)C(NC(=O)c1cc2cc(F)ccc2[nH]1)c1nccn1C +Cc1cnc(NC(=O)CCCn2nnc3ccccc3c2=O)s1 +CC(=O)c1ccc(OC(=O)Cc2ccccc2C)cc1 +CCC1c2ccsc2CCN1C(=O)NCc1ccc(C)nc1 +N#CCCN(CCC#N)C(=O)Nc1cccc(C(F)(F)F)c1 +O=C(Cn1cnc2sccc2c1=O)c1ccc2c(c1)OCCO2 +Cc1ccn2cc(C(=O)Nc3cc(S(C)(=O)=O)ccc3C)nc2c1 +CC(C)CC(=O)NCCNC(=O)c1n[nH]c2c(Cl)cccc12 +COc1cccc(C(N)=O)c1OCc1nnc(-c2ccccc2)o1 +COC(=O)c1sc(NC(=O)CCc2cccnc2)nc1C +O=C(Oc1ccc2cn[nH]c2c1)C1CCN(c2ncccn2)CC1 +CCOC(=O)c1cnc(OC)nc1-c1ccccc1Cl +CC(C)CNC(=O)c1ccccc1NC(=O)Cn1ccccc1=O +CC(C)OCc1ccccc1CNC(=O)c1ccc(=O)[nH]c1 +CC(C)COc1cccc(C(=O)OCC(N)=O)c1 +CC(c1ccccc1)N(CC(N)=O)C(=O)c1ncn(-c2ccccc2)n1 +Cc1csc(SC(C)C(=O)NC2(C#N)CCCCC2)n1 +O=C(c1ccc(Cn2cc(Br)cn2)o1)N1CCOCC1 +Cc1ccnc(NC(=O)c2csc(-c3cnccn3)n2)c1 +O=C(CN1CCN(CCO)CC1)N(Cc1ccccc1)C1CC1 +COCCNC(=O)c1ccc(Oc2ccccc2)cc1 +CCS(=O)(=O)NCCNC(=O)c1ccc(Br)cc1C +Clc1ccc(-c2noc(-c3ccc(N4CCOCC4)nn3)n2)cc1 +CC(=O)NCCC(=O)NCc1cccnc1Oc1ccc(F)cc1F +CC1CCN(C(=O)NCCN2CCOCC2)C(C)C1 +N#Cc1cc(CNc2cccc3[nH]ccc23)ccc1F +COc1cc(OC)cc(C(=O)Nc2ccc(C#N)cn2)c1 +CCOC(=O)N1CCN(C(=O)c2ccccc2CC#N)CC1 +N#CC(CCCCOc1ccccc1)C(=O)N1CCCC1 +Cc1ccc(C(=O)OC(C)C(=O)c2ccc(Cl)cc2)o1 +COc1cccc(C(=O)NCc2ccccc2)c1O +Cc1ccncc1NC(=O)NC1(c2ccccc2F)CC1 +Cc1cccc(OC(=O)C2CCCCN2S(C)(=O)=O)c1C +Cc1noc(C2CN(C(=O)Cc3ccc(Cl)cc3)C2)n1 +CC(=O)c1cccc(NC(=O)N2CCN(C)c3ccccc32)c1 +Cc1cc(C)n(-c2ccc(C(=O)NCc3nc(C)c(C)o3)cc2F)n1 +O=C(C1CC1)N1CCC(c2nc(C3CC3)ncc2-c2ccncc2)CC1 +COc1ccc(C)cc1CSc1nnnn1C1CC1 +Cc1ccc2ncn(CC(=O)NC(C)(C)C)c(=O)c2c1 +C=CCNC(=O)Nc1ccccc1S(=O)(=O)N1CCCCC1 +COC(=O)CNS(=O)(=O)c1ccc(CC(C)C)cc1 +COC(=O)CN(C)c1ncc(Br)c2c(N)cccc12 +CC(C)(C)OC(=O)N1CCC(CC(O)C(F)(F)F)CC1 +Cn1c(SCC(=O)NCC2CCCO2)nnc1-c1ccco1 +Cc1ccc(C(=O)NCC(O)c2cccc(C(F)(F)F)c2)o1 +COc1ccnc(NC(=O)c2sc(C)cc2OC(F)F)c1 +O=C(NCc1ccccn1)c1cncc(Br)c1 +CSc1ccccc1NS(=O)(=O)c1c(C)n[nH]c1C +CC(Oc1ccccc1Cl)C(=O)NCc1cnn(C)c1 +CC(C)C(=O)Nc1ccc(NC(=O)c2cnccn2)cc1 +O=C(Cc1ccc[nH]1)NCc1ccccc1OC1CCC1 +CC(=O)NCCc1nc(C2CC2)nn1-c1cccc(C)c1C +c1ccc2sc(CN3CCOC(c4nccs4)C3)cc2c1 +Cc1c[nH]c(C(=O)N2CCC(O)(C3CCC3)C(C)C2)n1 +CC(=O)N1CCN(CCNC(=O)c2ccc(Cl)cc2)CC1 +CC(C)c1nnc(SCC(=O)Nc2cccc(Cl)c2)n1C +CC(C)Oc1ccc(CCNC(=O)Nc2cccnc2)cc1 +CNc1nc(CNC(=O)Nc2ccccc2OC(C)C)cs1 +CCc1noc(CN(C)C(=O)C2CC2c2ccc(C(C)C)cc2)n1 +CC(C)CN(CC(C)C)C(=O)NCCC(=O)N1CCCC1 +Cc1ccc(N(CC(=O)N2CCCC2)S(C)(=O)=O)c(C)c1 +COc1cc(N)c(CCN2CCCC2=O)cc1OC +O=C(C1CCCC1)N1CCN(Cc2cc(-c3ccco3)on2)CC1 +CCC(=O)N(Cc1ccco1)CC1CCOC(C)(C)C1 +Cc1ccc2c(Cl)c(C(=O)N3CCN(C)CC3)sc2c1 +Nc1nc(SCC(=O)Nc2nc3c(s2)CCCC3)n[nH]1 +COc1ccc(OC)c(NC(=O)C(C)OC(=O)c2c(C)noc2C)c1 +CCC(C)(C)C(=O)N1CCN(c2ccccc2F)CC1 +O=C(Cc1ccc2c(c1)OCC2)N1CCc2ccccc2C1 +Cc1ccc(CN(C(=O)c2ccc(F)cc2)C2CC2)cc1 +Cn1cc(C(=O)NC(C2CC2)C2CC2)c(=O)[nH]c1=O +CC(C)c1nnc(NC(=O)Cn2c(=O)sc3ccccc32)s1 +CCCC(=O)N1CCN(Cc2nc(-c3ccc(OC)cc3)no2)CC1 +O=C(Cn1nnc(-c2cccs2)n1)Nc1ccc2c(c1)CCC2 +CC(C)Oc1ccc(CNC(=O)Cc2ccc[nH]2)cn1 +CNC(=O)c1cc(Cl)ccc1NCC(=O)OC +O=C(NCc1cc(-c2ccccc2)on1)Nc1ccc2c(c1)OCO2 +O=C(c1ccco1)N1CCn2cccc2C1c1ccccc1 +COc1ccccc1CC(=O)Nc1cnc2n1CCCC2 +CCc1cnc(NC(=O)NCCCc2c(C)noc2C)s1 +OC(Cc1c(F)cccc1Cl)c1cnccn1 +CC(C)CCC(=O)Nc1ccccc1-n1cncn1 +Cc1ccccc1C(=O)N1CCCC1c1nc(C2CC2)no1 +c1ccc(CNc2ncc(-c3nccn3Cc3ccncc3)cn2)cc1 +O=C(CNC(=O)c1cccc(F)c1)Nc1ccn(-c2ccccc2)n1 +Nc1cc(-c2nnc3n2CCCCC3)c(F)cc1F +COC(=O)Cn1c(=O)[nH]c2cc(OC)c(OC)cc21 +CC(C)C(NC(=O)CCNC(=O)c1ccccc1)c1ccc(F)cc1 +O=C(Cc1ccc(F)cc1)N(Cc1ccccc1)C1CC1 +CC(C)N1CCC(Nc2ccccc2Oc2ncccc2C#N)C1=O +COCCCNc1cc(OC)nc(C(C)(C)C)n1 +COc1ccc(OCCCNC(=O)c2ccc(=O)n(C)c2)cc1 +O=C1Nc2ccc(F)cc2C1NCCc1ccccn1 +CCC(=O)Nc1ncc(Cc2cccc(F)c2)s1 +CN(C)c1ccc(S(=O)(=O)N2CCOCC2)cc1N +CC(CC(=O)Nc1cc[nH]n1)S(=O)(=O)c1ccc(F)cc1 +Cc1ccc2ncnc(Sc3ccccn3)c2c1 +Cc1ccccc1CNC(=O)Cn1ccccc1=O +NC(=O)C1CCCCCC1NC(=O)CCCc1ccccn1 +Cc1nc(CN(C)CC(c2cccs2)N2CCOCC2)no1 +Cc1cccc2c(=O)n(CC(=O)OC3CCCC(C)C3)cnc12 +CN(C)C1C=C(OC2CC2)C=C(NS(C)(=O)=O)N1 +CNC(=O)CN(C)C(=O)Cc1c[nH]c2ccccc12 +CCOC(=O)c1ccc(NC(=O)CCc2nc(C)no2)cc1 +COc1ccccc1CC(=O)N(Cc1ccncc1)Cc1cccnc1 +N#Cc1c(-c2ccco2)cc(-c2cccnc2)nc1N +CC(C)CCOCCS(=O)(=O)c1nccn1C +COC(=O)CCC(=O)Nc1ccc(Nc2ccccc2)cc1 +Cc1cc(NC(=O)Cn2cc(Cl)cn2)n(C(C)(C)C)n1 +COc1cc(C(=O)N2CCCCC2)cc2c1OCCO2 +C=CCn1c(CNC(=O)c2cccnc2)nc2ccccc21 +Cc1nn(CC(C)C)c(C)c1CC(=O)NC(C)c1nnc2n1CCC2 +CC(=O)Nc1ccc(C(=O)Nc2cnc3c(cnn3C(C)C)c2)cc1 +Cc1csc(NC(=O)COC(=O)CCn2c(C)csc2=O)n1 +CC(=O)Nc1ccc(CNc2nnc(Cc3ccccc3F)o2)cc1 +COCCCC1CCCN(C(=O)c2ccc(C(C)=O)cc2)C1 +COc1cccc2sc(N3CCN(C(=O)C(C)C)CC3)nc12 +COC(=O)CCCSc1nnc(-c2cccs2)o1 +CC(C)n1cc(C(=O)NC2CC(=O)N(CC(C)(C)C)C2)cn1 +CCOC(=O)C1CCCN(C(=O)CCc2c[nH]c3ccccc23)C1 +O=C(c1cccc2[nH]ccc12)N1CCC2(CCOC2)C1 +CCc1ccc(CN(C(=O)CNC(=O)C(C)(C)C)C2CC2)cc1 +Cc1ccc(C(C)Nc2ccc(CNS(C)(=O)=O)cc2)cc1 +Cc1ccn2c(=NC(=O)CCCSc3ccccc3)[nH]nc2c1 +COc1cccc(C(=O)Nc2cccnc2OC(C)C)c1F +Cc1cc(CN2CCN(C(=O)c3cccc(C)n3)CC2)on1 +N#Cc1csc(CN2CCC(Oc3ccccc3)CC2)c1 +O=C(NCC(O)c1ccc(Cl)cc1)C1CCCCC1 +Cc1ccccc1CN(C)C(=O)CNc1ccccc1 +Fc1ccc(Cn2nnc(-c3ccccc3)n2)cc1 +CC(OCC1CCCCO1)C(=O)NC(C)c1ccc2c(c1)OCCO2 +CCC1c2ccccc2CCN1C(=O)CNC(=O)OC +c1ccc(-c2noc(N3CCN(c4ncccn4)CC3)n2)cc1 +CCCc1cc(C(=O)NCCc2cccnc2)n(C)n1 +CCCCSc1nc(N)cc(N2CC(c3cccnc3)C2)n1 +COc1ccc(OC)c(NC(=O)CCSc2ccccn2)c1 +CC(C)(C)n1nc(C(=O)Nc2ccc3c(c2)C(=O)NC3)cc1C1CC1 +Cc1ccc(N2CCCn3c2nc2c3c(=O)n(C)c(=O)n2C)cc1 +O=C(Nc1cn[nH]c1)NC1CCC2(CC1)OCCO2 +O=C(c1cccs1)N1CCN(CC(O)c2cccs2)CC1 +Cc1cc(C)n(CC(C)CNC(=O)C2COc3ccccc3O2)n1 +O=C(NCc1ccccc1)c1cc2nccc(-c3ccc(F)cc3)n2n1 +CSc1ccc(CNS(=O)(=O)C(C)C)cc1 +O=C(CSc1nnc(Cc2ccccc2)o1)c1ccc[nH]1 +Cc1ccnc(NC(=O)c2cccc(COc3ccc(C)nc3)c2)c1 +CC(O)C1NC(=O)C2CN(C(=O)Oc3ccccc3)CCN2C1=O +O=C(NCc1ccccc1-n1ccnc1)Nc1cccnc1 +COc1ccc2c(c1)N(Cc1cccnc1)CCO2 +COc1ccc(CN2CC(C(=O)NCc3ccsc3)CC2=O)cc1 +CCC(NC(=O)c1ccccc1)c1nc(C)cs1 +CCOC1COC2(CCN(C(=O)CC3Cc4ccccc4C3)C2)C1 +CCNC(=O)CN(CC)C(=O)c1cc(C)n(-c2cc(C)on2)c1C +COc1cccc(C2NCCc3cc(F)c(O)cc32)c1 +CCCC(C)C(=O)Nc1ccccc1C(=O)NC1CC1 +Cc1cccc(OCC(=O)Nc2c(C)cc(C)nc2C)c1 +O=c1[nH]c(NCc2ccc3c(c2)OCO3)nc2ccccc12 +CC(=O)N(C)C1CCN2CCC(=O)Nc3cccc1c32 +CCc1nn(C)c(OC)c1CN1C(C)COC(c2ccccc2)C1C +NC(=O)c1oc2ccccc2c1NS(=O)(=O)c1ccc(F)cc1 +N#Cc1cccc(NC2COc3cc(O)ccc32)c1 +O=C(CC1NCCc2ccccc21)N1CCCCCC1 +CC1C(=O)NCCN1C(=O)c1cccc2ccccc12 +Cc1nc(C)c(C(=O)NC(C)c2ccc(Cl)cc2Cl)s1 +COc1ccc(OC)c(C(=O)N2CCNC(=O)C2C)c1 +CCOC(=O)c1c(CC(C)C)csc1NC(C)=O +CCCC(=O)N1CCCC1C(=O)NCCNC(C)=O +Cc1ccc(OCCCNC(=O)C2CNC(=O)N2)cc1 +CCc1ccc(C(=O)Nc2ccc3c(c2)C(=O)N(C)CCO3)cc1 +CCN(Cc1cccc(C)c1)C(=O)NCCOC +CCCCc1c(CO)nnn1Cc1ccc(C)cc1 +CC(C)(C)CN1CCOC(CCNC(=O)c2ccncc2)C1 +CCCNC(=O)Cn1cccc1-c1nc(-c2ccc(C)cc2)no1 +N#Cc1ccc(F)c(CN2CCCC2c2ccc3c(c2)OCCO3)c1 +Cc1cccc(CNc2cccc(C(N)=O)c2)c1C +O=C(CSc1cn[nH]n1)Nc1cccc(N2CCCC2=O)c1 +COc1cccc(CNC(=O)c2nnc3ccc(OC)cc3n2)c1 +CCS(=O)(=O)c1ccccc1C(=O)NCCN1CCOCC1 +CC(=O)c1cccc(NC(=O)Nc2ccn(Cc3cccnc3)n2)c1 +Cc1nccc(N2CCC(c3n[nH]cc3C)CC2)n1 +CC(C)CNC(=O)NCc1ccccc1OCC(F)(F)F +COc1ccc(C)cc1NC(=O)c1cc(Br)c[nH]1 +CCCC1CN(C(=O)C2CCCN(C(=O)OCC)C2)CCO1 +CN(C)C(C(=O)NCC1=CCCCC1)c1cccc(F)c1 +NC(=O)C(NCC1CCCc2ccccc21)c1ccccc1 +Cc1cc(C(C)C(=O)N(C)c2ccc(Br)cn2)c(C)o1 +Cc1c(C(=O)N(C)CCC(F)(F)F)cnn1-c1cccc(Cl)c1 +O=C(Cc1ccccc1)NCC1(c2ccccc2)CCOCC1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)Nc1cccnc1 +O=C(Nc1cnccn1)c1ccc(-n2cncn2)nn1 +Cc1c(C(=O)NC2CCC(C)CC2)sc2nc3n(c(=O)c12)CCC3 +CN(Cc1nc2ccccc2s1)C(=O)Nc1ccc2c(c1)COC2 +Cc1ccc(CNC(=O)OC(C)(C)C)c(N(C)C)c1 +CC1CCCN(C(=O)C2CN(C(=O)c3cccs3)C2)C1 +COCCN1CC(C(=O)N(C)C(C)c2ccc(Cl)cc2)CC1=O +CC(CNC(=O)NC1CCCNC1=O)Cc1cccs1 +CC(C)C(Sc1cccs1)C(=O)NCc1cccnc1 +CCN(CC)C(=O)c1ccccc1NC(=O)Cc1c(C)noc1C +CC1CCC(N(C)C(=O)c2cccnc2OCC(F)F)CC1 +COC(=O)c1ccc(C(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1 +Cn1ccc(CNC(=O)Cc2ccccc2NC(=O)OC(C)(C)C)c1 +C#CCNC(=O)NCc1nnc2c(Cl)cc(C(F)(F)F)cn12 +COC(=O)C(NC(=O)c1ccc[nH]c1=O)C(C)C +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)NC(C)C1CCCO1 +CCC1CCN(C(=O)NCCNC(=O)C(C)C)CC1 +CSc1nc(C)c(CCC(=O)N2CCC(C)CC2C)c(=O)[nH]1 +CCc1nc(C2CCCN2c2ncc(C#N)cc2Cl)no1 +O=C(Nc1cccc2cnccc12)c1cc2scnc2[nH]1 +CC(OCC1CCCO1)C(=O)Nc1ccc2nc(C3CC3)sc2c1 +Cc1cnc(NC(=O)CCC(=O)c2ccc(Cl)cc2)s1 +COc1ccc(OC)c(NC(=O)CNc2ccccc2C(N)=O)c1 +CC1(C)COCCN1C(=O)c1cn2ccccc2n1 +COc1ccc(F)cc1NC(=O)c1scnc1C1CC1 +Cn1ccnc1Cn1c(CO)nc2ccc(F)c(F)c21 +CCC(CC)C(=O)c1ccc(S(C)(=O)=O)cc1 +CCCCCNC(=O)c1ccc(NC(=O)CC)cc1 +CC(C)c1ccc(C(=O)Nc2ccnc3ccnn23)cc1 +O=C(CNc1cccc(C(F)(F)F)n1)N1CCc2sccc2C1 +COc1cccc(N2CCN(c3ncnc4[nH]cnc34)CC2)c1 +Cn1ccnc1CN1CCCN(C(=O)COc2ccccc2)CC1 +CC(=O)Nc1ccc(C(=O)Cn2cnc3ccccc3c2=O)cc1 +Cc1cc(C(=O)N2CCC(CCOCc3cccc(F)c3)CC2)no1 +O=C(COc1ccc(F)cc1)N1CCN(CC(O)c2ccco2)CC1 +O=C(NCc1ccc(Cl)cc1)c1nc(-c2cnccn2)no1 +Cc1noc(C2CN(S(=O)(=O)c3cccs3)C2)n1 +O=C(Nc1c(-c2ccccc2)nc2ncccn12)c1ccc(F)cc1 +Cc1nc(OCC(=O)NCc2ccc(F)cc2)c2ccccc2n1 +CC(C)Cc1nc2cc3c(cc2n1CCO)OCCO3 +COc1ccccc1CC(=O)NCCNC(=O)c1ccc(C)c(F)c1 +Cn1nnnc1SCC(=O)c1cc2ccccc2oc1=O +CCCC1CN(C(=O)c2ccn(C3CCCC3)n2)CCO1 +Cc1cc(C(=O)N2CCCC(CO)(CC3CC3)C2)ccc1F +CCN(C)c1ccc(C(=O)Nc2ncccc2C)cc1 +COc1ccccc1S(=O)(=O)Nc1cnccc1C +O=C(NCCc1csc(N2CCCC2)n1)c1scnc1C1CC1 +CC(C)Cn1ncc(C(=O)N(C(C)C)C2CCOCC2)c1C(F)F +CCOc1cccc(C(=O)N(Cc2ccco2)c2ccccn2)c1 +COc1ccccc1C(C)N(C)C(=O)CCNS(C)(=O)=O +CCc1cccc(C)c1NC(=O)CSc1nc(C)cs1 +O=C(NCC1(CO)CC1)c1cccc2ccccc12 +COc1ccc(-c2cc(N)c(=O)n(CC(C)C)n2)cc1Cl +CN(C)C(=O)c1ccc(Cl)c(NC(=O)c2cccnc2N(C)C)c1 +Cc1cc(C)n(CC(C)CNC(=O)C(C)Sc2ccccn2)n1 +Cc1ccc(C)c(NCC(=O)N(CCC#N)CCC#N)c1 +COc1ccc(CNc2cccc(F)c2C(C)=O)c(OC)c1OC +CC(C)(O)CN1CCN(C(=O)Cc2cccc(Cl)c2)CC1 +CCCNC(=O)CNC(=O)c1ccc(Br)c(F)c1 +Cc1c(NC(=O)C2CCCO2)cccc1C(=O)Nc1nccs1 +Cc1ccc(NC(=O)N(CCCO)Cc2ccncc2)s1 +O=C(NCC1CN2CCCCC2CO1)c1cccs1 +COCc1ccc(CNC(=O)c2cccc(OC)c2F)cc1 +CCOC(=O)Cc1nc2cc(C)c(C)cc2[nH]c1=O +COc1cccc(CNC(=O)N2CCCC2c2c(C)n[nH]c2C)n1 +Cc1nc(CNS(=O)(=O)c2c(F)cccc2Cl)oc1C +COc1ccc2c(c1)CCCC2CNC(=O)CCn1cncn1 +COc1ccccc1C1Nc2ccccc2C(=O)N1C1CC1 +NC(=O)c1cccc(NC(=O)c2c(Cl)ccc(Cl)c2Cl)n1 +CC(=O)C(C)N1C(=O)C(C(C)C)Oc2ccc(N)nc21 +Cc1ccc(-c2ccnc3c(C(=O)NCC(C)O)cnn23)cc1C +CNC(=O)c1ccc(CNC(=O)CC2CCCCC2)cc1 +COCC(=O)NCc1sc(-c2cccs2)nc1C +COCC1CN(C(=O)c2cnccn2)Cc2cnn(C)c21 +CC1CN(C(=O)CS(=O)(=O)c2ccccc2Cl)CC(C)O1 +Brc1cccc(OCc2ccncc2)c1 +O=C(CSc1cccc2cccc(Cl)c12)N(CCO)CCO +Fc1cccc(-c2noc3c2CN(CCn2cc(Cl)cn2)CC3)c1 +Cc1snc(S(=O)(=O)Cc2c(F)cccc2Cl)c1C#N +COc1ccc(C(C)N(C)c2cc(C(N)=O)ccn2)cc1 +COc1ccc(CNc2ncnc3c2cnn3-c2ccccc2)cc1 +Cc1cc(C)n2nc(C)c(C(=O)NCCN(C)S(C)(=O)=O)c2n1 +C#CCCC(=O)Nc1c(C(C)C)cccc1C(C)C +O=C(NCCc1ccccc1)c1cc2c(=O)n3ccccc3nc2s1 +CCOCc1ccccc1CNC(=O)Nc1cnccc1C +CS(=O)(=O)c1ccccc1NCCc1ccco1 +COCCN1C(=O)c2n[nH]c(C)c2C1c1cccc(O)c1 +COCc1ccc(C(=O)OCc2cc(=O)oc3cc(OC)ccc23)o1 +CS(=O)(=O)NCCCNC(=O)c1cncn1-c1ccc(F)cc1 +CNC(=O)C1CCCN1C(=O)c1ccccc1F +c1cnc2ncc(CN3CCCC(c4nccs4)C3)n2c1 +Clc1cccc(NCc2nc(C3CC3)no2)c1-n1cccn1 +O=C(Cc1cccc2ccccc12)Nc1ccc(N2CCOCC2)nc1 +COc1ccc(S(=O)(=O)N2CCNC(=O)C2C(C)C)c(C)c1C +O=C(c1cnccn1)N1CCC(Nc2cccn3ncnc23)CC1 +O=C(CCCNC(=O)c1ccccc1)Nc1nc[nH]n1 +O=S(=O)(C1CC1)N1CCC(Oc2ncccn2)CC1 +COc1ccc(-c2ccn3nc(N)nc3c2)cc1Cl +CCOc1ccc(C(=O)Nc2ccc(-n3nc(C)cc3C)nc2)cn1 +Fc1ccc(COc2ccc(Cl)cc2CNc2ncn[nH]2)cc1 +COC(=O)CC1(NC(=O)CCC2CCCC2)CCOCC1 +Cc1cccc(CNc2cnn(-c3ccccc3)c(=O)c2Cl)n1 +COCCS(=O)(=O)N1CCCc2cc(N)ccc21 +Cc1csc(Sc2ccc(NC(=O)Cc3cc(C)on3)cc2)n1 +CCC(Oc1ccccc1F)C(=O)Nc1nccn(C)c1=O +COc1ccccc1N1CCN(Cc2ccccc2F)C(C)C1=O +Cc1ncsc1Cn1ncc(N(C)CCc2ccccc2)cc1=O +Cc1cc(C)c(OCC(=O)Nc2cccc(N)c2)c(Br)c1 +CN(Cc1cccc(Cl)c1)C(=O)c1ccc2cc[nH]c2c1 +CC(NC(=O)CNC(=O)Nc1ccccc1)c1ccccc1 +CC(=O)Nc1nc(C(=O)N(C)CC(C)C)cs1 +CCn1nc(C(C)(C)c2cc(N)n(CC)n2)cc1N +Cc1cc(C)n(CCNC(=O)c2nnc3ccccc3n2)n1 +CN(C)c1c(Cl)cccc1NC(=O)NC(C(N)=O)C(C)(C)C +CCCNC(=O)CN(C)C(=O)c1ccc2c(c1)nnn2CC +CC(C)N(CCSc1ccccc1)C(=O)c1ccc[nH]1 +Cc1cc(Cn2nnc(-c3ccc(F)cc3)n2)no1 +OCC(O)C1NCCc2cc(Br)cc(F)c21 +O=C(c1cnn2c1OCCC2)N1CCN(CCO)CC1 +O=C(CC1Sc2ccccc2NC1=O)NCC1CCCO1 +Cc1cc(C)c2c(NS(C)(=O)=O)nn(C)c2n1 +COc1ccc(-c2nc(C#N)c(C#N)nc2C(C)C)cc1OC +CCC1CCCN(C(=O)CN(C)C(=O)c2ccccc2)C1 +CNC(=O)c1ccc(CS(=O)c2cccc(Cl)c2)o1 +Cc1cccc(OCc2nnc3sc(-c4ccncc4)nn23)c1 +O=C(NCC(=O)N1CCCC1)c1ccccc1OC(F)F +CCN(CC)C(=O)C1CCCCN1C(=O)c1ccccc1 +Cc1ccc(C(=O)N2CCN3C(=O)C(C(C)C)NC(=O)C3C2)cc1 +CCc1ccc(C(=O)N2CCC(C(=O)Nc3ccccc3)CC2)o1 +COc1ccc2[nH]cc(C3=CCN(C(=O)c4cccc(C)n4)CC3)c2c1 +COc1c(CN(C)CCc2ccc(F)cc2)c(C)nn1C +O=C(Cc1cccnc1)N1CCC(OCc2ccccc2)CC1 +CC(=O)N(C)CC(=O)Nc1ccc(Oc2cccc(F)c2)cc1 +O=C(OCC(F)(F)C(F)F)c1ccc(-n2ccnn2)cc1 +CC1(NC(=O)c2ccc(-n3cncn3)c(F)c2)Cc2ccccc2C1 +Cn1nccc1CNC(=O)Nc1ccc(OCC2CCOCC2)cc1 +O=C(NCc1ccc(-n2ccnc2)cc1)c1cc2ccccc2oc1=O +O=C(Cc1ccccc1)NCCCNC(=O)c1cccs1 +Cc1cc(Cl)ccc1N(CC(N)=O)S(C)(=O)=O +O=C(NCCNC(=O)N1CC2CC=CCC2C1)C1CCCC1 +Cn1cc(C(=O)NCc2ccc3c(c2)OCCO3)cn1 +CCC1CN(C)c2ccccc2CN1C(=O)Cn1ccnc1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCCC1Cc1ccccc1 +CC(C)n1cc(NC(=O)c2cc(NC(=O)C3CCCC3)n(C)n2)cn1 +CC(C)NC(=O)CCNC(=O)NC(C)C(C)CO +NC(=O)C1(CNC(=O)C2(c3ccc(F)cc3)CCC2)CCOCC1 +CC(C(=O)N1CCCC1)N(c1ccccc1)S(C)(=O)=O +CC1CCCC(N(C)C(=O)CCn2cnc3sccc3c2=O)C1 +O=C(Cn1nnc(-c2ccccc2)n1)Nc1nc2ccc(F)cn2n1 +COCCNC(=O)CCC(=O)c1ccc(F)c(C)c1 +N#Cc1ccc2c(ccn2CC(=O)Nc2ccnn2-c2ccccc2)c1 +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1ccc(-n2cccn2)cc1 +Cc1ccc(C(=O)CSc2nnc(-c3cccnc3)n2C)cc1 +Cc1ccc(C(N)=O)cc1NC(=O)Nc1ccccc1OCC1CC1 +COc1ccc(CNC(=O)N(C)C(C)C)c(C(F)(F)F)c1 +O=C(NCC12COCC1CN(c1ncc(F)cn1)C2)c1ccnnc1 +Cc1ccc(CNC(=O)NCCCNc2ccccc2)s1 +CCC(=O)NCC(=O)NC1CCC(C(=O)NC)CC1 +COCCN(Cc1ccc(C#N)cc1)C(=O)c1ccccc1F +O=C(Nc1ccc(F)c(Cl)c1)c1ccc(-n2cccn2)nn1 +Cc1cccc(Cl)c1NC(=O)N(C)Cc1ccncc1 +Brc1ccc2[nH]c(C3COC3)cc2c1 +Fc1ccc(-n2nc(-c3ccco3)nc2C2COCCO2)cc1F +CCc1nc2nnc3c(=O)n(CCCO)ccc3n2n1 +O=S(=O)(Oc1ccccn1)c1ccc(F)cc1 +CC(=O)N1CCN(C(=O)c2cc3n(n2)CCCC3)CC1 +COc1ccc(NC(=O)C2CC(=O)N(c3cccc(C)c3C)C2)cn1 +CCc1noc(CC)c1CNC(=O)NCc1nc2ccccc2s1 +Cc1ccc(NC(=O)CCNC(=O)NCc2cccs2)nc1 +COc1cc(N)c(CCC(=O)N2CCCCC2)cc1OC +CC(C)c1ncc(Cl)c(C(=O)NCC2CC=CCC2)n1 +CCOc1cc(C#N)ccc1OCC(=O)Nc1cnn(C)c1 +Cc1cc(C)c(C(=O)NCCCc2ccc(O)cc2)c(=O)[nH]1 +Fc1cccc(CSc2nnc3n2CCCCC3)c1 +CC(C)c1nnc(CNC(=O)c2ccc(-c3ncon3)cc2)n1C +Cc1nn(C)c(C)c1CC(=O)Nc1nnc(-c2ccco2)s1 +CCC(C(=O)NC)n1nc(C)c2sc3ccccc3c2c1=O +O=C(c1cccc(O)c1)N1CCN(Cc2cccc3ccccc23)CC1 +CCCNS(=O)(=O)c1ccc2c(c1)N(C)C(=O)C(C)O2 +CC(C)NC(=O)CN1CCN(C(=O)c2cccc(N(C)C)c2)CC1 +COC(=O)c1occc1Cn1cnc2ccsc2c1=O +O=C(c1cn[nH]n1)N1CCCOC(Cn2cccn2)C1 +CN(C)c1cc(C(=O)Nc2ccc(-c3ncc[nH]3)cc2)ccn1 +CCSc1nnc(CNc2ccc(F)cc2)n1CC1CCCO1 +O=C(NCCCn1ccc2ccccc21)Nn1cnc2ccccc21 +CC(=O)c1ccc2c(c1)N(CC(=O)NC1CCCCC1)CCO2 +N#Cc1c(F)cccc1NC(=O)COc1ccc(Cl)cc1 +COc1ccc(-c2nc(C)c3c(n2)sc2c(=O)n(C)nnc23)cc1 +Fc1ccc(Cc2nnc3sc(-c4csnn4)nn23)cc1 +O=C(CCNC(=O)c1ccccc1)Nc1cccc2ncccc12 +CCCCN(C)C(=O)CSc1nc(O)c(C(C)C)c(=O)[nH]1 +Cc1occc1C(=O)NCC(=O)NCc1ccc(C(C)(C)C)cc1 +O=C(NCc1ccc(-n2cncn2)cc1)Nc1cc(Cl)ccc1F +CC(C)Oc1ccc(CNC(=O)c2cnc(C3CCCO3)s2)cc1 +COc1ccc(F)c(NCC(=O)NC(C2CC2)C2CC2)c1 +Cc1nc2ccc(C(=O)NCCN3CCOC3=O)cc2nc1C +CC(C)(Oc1ccc(Cl)cc1)C(=O)N1CCC(O)C1 +COCCN1CC2CN(Cc3cn(C)c4ccccc34)CCN2C1=O +NC(=O)c1ccc(=O)n(Cc2cc(Cl)c3c(c2)OCO3)n1 +CC(=O)c1ccccc1NC(=O)c1ccc(OC(C)C)nc1 +CC(C)c1nc2cc(O)ccc2n1Cc1nccn1C +O=C(CCCOc1ccc(F)cc1F)N1CCCS1(=O)=O +Cc1cnn(CCC(=O)NC(C)c2cccc(C(F)(F)F)c2)c1 +Cc1ccc(CNC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +Cc1nc2ccccc2nc1SCC(=O)N1CCN(C)CC1 +CCOc1ccc(F)c(C(=O)N2CCC(OCCC(C)C)C2)c1F +CCn1cc(CN2CCN(C(=O)c3cccc(OC)c3)CC2)cn1 +Cc1nn(Cc2cccc(Cl)c2)c(C)c1NC(=O)C1CC1 +COCCNC(=O)N1CCC(C(=O)N(C)C(C)C)CC1 +NC(=O)CN1CCc2c(N)cc(Br)cc2C1 +CN(Cc1cc(Br)cs1)C(=O)Nc1cccc(N)c1 +Cc1ccc(-c2ccnc(N3CCc4n[nH]cc4C3)n2)c(C)n1 +COc1cc2nc(N)n(Cc3ccc(C)cc3)c2cc1OC +CCc1sc(C(=O)N2CCN(c3nccs3)CC2)cc1C +O=C(NCc1cccnc1)NCC1(c2ccc(F)cc2)CCCC1 +Cc1cncc(C(=O)Nc2c(C)cccc2Cl)c1 +CCc1nc(CN(C)C(=O)Cc2ccccc2OC(C)C)cs1 +CCCNc1cccc(C(=O)N(C)C(C)CCC)n1 +CCCCN(CCO)C(=O)c1cc2c(C)cc(C)cc2[nH]1 +CCCOC(=O)c1ccc(S(=O)(=O)Nc2cc(C)nn2C)cc1 +Cn1c(C(=O)Nc2cccc(Cl)c2Cl)cccc1=O +Cc1cc(NC(=O)c2ccc3c(=O)n4c(nc3c2)CCCC4)no1 +CC(C)C(NC(=O)COc1ccccc1)C(=O)Nc1nncs1 +CC(OCC(F)(F)F)C(=O)OCC1COc2ccccc2O1 +Cc1nc(OCC(=O)Nc2ccc(C)c(C)c2)c2ccccc2n1 +Clc1ccccc1COc1cccc(-n2cnnn2)c1 +CCCn1nc(C(=O)Nc2cc(Cl)cc(Cl)c2)ccc1=O +CCCC1CN(C(=O)Cc2cccc(Cl)c2)CCO1 +CNS(=O)(=O)c1cc(C(=O)NCC(C)c2ccccc2)n(C)c1 +Cc1cnc(C(=O)Nc2cc(Cl)ccc2N2CCOCC2)cn1 +O=C(NC1CCCCCC1CO)c1cccc2cc[nH]c12 +C=CCN1CCN(C(=O)c2csc(CCC)c2)CC1 +CCc1cnc(N2CCC3(CC(=O)N(c4cccc(C#N)c4)C3)C2)nc1 +CCc1cccc(C)c1NC(=O)COc1cccc2c1CCCC2O +O=C(c1cccnc1)c1ccccc1Br +CC1CN(C(=O)CCC(=O)NCc2cccnc2)c2ccccc2O1 +O=S(=O)(CCc1ccccc1)c1ccc(Br)cc1 +Cc1cnc(C(=O)OCC(=O)c2ccc3c(c2)OCCO3)cn1 +CCCCN(CC(F)(F)F)C(=O)c1ccccn1 +COC1CCN(C(=O)c2cnn(-c3ccccc3)n2)CC1 +Cc1noc(C(C)C)c1C(=O)OCc1nc2c(C)cccc2c(=O)[nH]1 +COC(=O)Nc1ccc(OCC(=O)Nc2ccc(C)cc2C)cc1 +Cc1nccnc1N1CCC(CNC(=O)OC(C)(C)C)C1 +Cc1n[nH]c(C)c1NC(=O)C(C)NC(=O)c1ccccc1 +COc1cc(OC)c(NC(=O)N(C)CC(O)C2CC2)cc1F +Cc1cc(C)c(S(=O)(=O)NCc2cn3ccsc3n2)c(C)c1 +CCc1cccc(NC(=O)c2cc(-c3cccnc3)on2)c1 +COCC(C)Nc1ncnc(NCc2ccccc2Cl)c1N +CCN(C(=O)c1cc(OC)c(OC)cc1F)C(C)c1ccncc1 +COc1cc(C)ccc1NC(=O)COc1ccccc1C#N +CCn1nc(C)c(NCc2cc(F)cc(C(F)(F)F)c2)c1C +COc1nccc(C(F)(F)F)c1C(=O)Nc1ccc(Cl)cc1 +CCn1cc(NC(=O)NCc2nc(Cc3ccccc3)no2)cn1 +Cc1nc(C2(NC(=O)c3ccco3)CCCCC2)no1 +O=C(Cn1c(NCCO)nc2ccccc21)c1ccc2c(c1)OCO2 +O=C(Nc1nncs1)c1ccc(-n2cnc3ccccc32)cc1 +Cc1n[nH]cc1CNc1ccc(Cl)c2ncccc12 +CCn1nc(C)cc1C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +Cc1ccc(=NS(=O)(=O)c2cc(S(C)(=O)=O)ccc2C)[nH]c1 +COc1cccc(-c2cc(-c3cc(O)ccc3OC)c(C#N)c(N)n2)c1 +CCCOc1ccccc1-n1nnc(C#N)c1C(C)C +O=C(C1CC1c1ccco1)N1CCCC1c1ccsc1 +CN(CCC(F)(F)F)C(=O)NCC(=O)Nc1ccccc1 +O=C(NCCNc1nc(C2CC2)nc2ccccc12)C1CCC1 +Cc1cc(CN2CCN(C(=O)c3csc(C)n3)CC2)on1 +CC(=O)Nc1nc(C(=O)N(C)CC(N)=O)cs1 +O=C(c1ccc(Cl)c(S(=O)(=O)NC2CC2)c1)C1CC1 +COCCOc1ccccc1NC(=O)c1ccc(Cl)cc1 +COc1ccc(CN2CCOCC2CC(C)C)cc1OC +Cc1nc2c(c(N(C)Cc3ccon3)n1)Cc1ccccc1OC2 +Cc1nc(-c2ccncc2)nc2c1CC(=O)N2Cc1ccccn1 +CC1CN(C(=O)COCC2CC2)CC1N1CCOCC1 +COc1ccc(NC(=O)C2CC3CCC2C3)c(OC)c1 +Cc1occc1C(=O)Nc1cccc(N(C)C(=O)c2ccoc2C)c1 +Cc1cc(C)cc(C2(C(=O)NCc3ccnc(C)n3)CC2)c1 +CN(C)c1ccccc1NC(=O)c1ccc(OC(F)F)cc1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cccnc3)CC2)cc1 +O=C(c1cc2cc(Cl)ccc2[nH]1)N1CCOCC1C1CC1 +CCOC(=O)Cc1csc(NS(=O)(=O)c2ccc(C)cc2)n1 +CCn1cc(NC(=O)c2ccnn2C(F)F)c(C(=O)OC(C)C)n1 +CCOc1ccc(C(=O)Nc2cccc(CO)c2)cn1 +COCCNC(=O)c1ccccc1NC(=O)Cc1ccc(C)c(C)c1 +CCc1nc2c(NC(=O)NCc3ccc(F)cc3)cccn2n1 +COC(=O)C(C)Oc1cc(-c2nccs2)ccc1N +CCc1ccc2occ(CC(=O)N3CCN(C)CC3)c2c1 +COC(=O)C(Cc1c[nH]cn1)NC(=O)c1ccccc1 +CCC(=O)N1CCCCC1C(=O)OCCc1c[nH]nc1C(F)(F)F +O=C(Cc1cnn(-c2ccccc2)c1)NCC1CCCO1 +Nc1cc(Br)c2c(c1)C(=O)CCCS2 +O=C(Nc1cccc(OCC2CCCO2)c1)c1ccc(F)cc1 +CCOCC(=O)N1CCN(C(=O)Nc2ccc(F)cc2)CC1 +NC(=O)C1Cc2ccccc2N1C(=O)CCSc1ccccn1 +O=C(NCC#Cc1ccccc1Cl)c1cc(-c2ccco2)on1 +CCS(=O)(=O)N1CCC(C(=O)OCC2CC=CCC2)CC1 +COc1cc(-c2ccc(S(=O)(=O)N3CCCCC3)cc2)ccc1O +Cc1cc(C)n(-c2ccc(NC(=O)N(C)CCC(C)C)cn2)n1 +Cc1cc2c(c(C(O)c3cccs3)c1)NC(=O)CC2 +CCCCCCN1C(=O)CS(=O)(=O)c2ccc(N)cc21 +Fc1ccc(-c2ccco2)cc1NCc1cn2cccnc2n1 +Cc1cccc(-n2ncc(C(=O)N3CCCC(C(N)=O)C3)c2C)c1 +CCS(=O)(=O)c1ccc(-c2cc(NC)ncn2)cc1 +CCn1c(=O)[nH]c2cc(C(=O)NCCCO)ccc2c1=O +Cc1cccc(C)c1NC(=O)c1sc(-n2cccc2)nc1C +C#CCOc1ccc(NC(=O)NCc2nc(C)sc2C)cc1 +CC(C)CCCCNC(=O)c1cnc2sccn2c1=O +COc1ccc2[nH]cc(CCNC(=O)c3cccc4c3ccn4C)c2c1 +CC(CCC(C)(C)C)NS(=O)(=O)N(C)C(C)C +CC(=O)c1cccc(OC(=O)c2cnn(C(C)(C)C)c2)c1 +CCCn1nnc(CO)c1-c1cc(OC)c(OC)c(OC)c1 +Cc1ccc(S(=O)(=O)N(C)C)cc1NCCCO +CC(C)(C)n1nc(C2CC2)cc1NC(=O)c1ccccc1 +COc1ccc(C)cc1Nc1nnc(SCCC(N)=O)s1 +Nc1nonc1C(=O)NC1CCCC(C(F)(F)F)C1 +Cc1nc(Cc2nc3scc(-c4ccccc4)c3c(=O)[nH]2)cs1 +O=C(Cc1cccs1)OCC(=O)N1CCCCCC1 +O=C(Nc1cccc(C(=O)Nn2cnnc2)c1)c1ccccc1 +Cc1cc(C(=O)Nc2nc(-c3c(C)[nH]c4ccccc34)cs2)on1 +CCCNC(=O)CNC(=O)NCc1cc(F)cc(Br)c1 +CCc1nnc(NC(=O)c2cc(C)nc(N(C)C)n2)s1 +CNC(=O)c1cccc(NC(=O)c2ccc3c(c2)CCCC3)c1 +Cc1ccc(C(=O)Nc2ccnn2C2CCCCC2)s1 +Nc1c(-c2ccccc2)noc1C(=O)N1CCCCC1 +CCCN(c1ccccc1F)S(=O)(=O)c1c[nH]c(C(=O)OC)c1 +CCn1nnc2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccc21 +CCCNC(=O)c1cccc(NC(=O)CNc2ccccc2)c1 +CC(C)CCN(C)C(=O)CSc1nnc(-c2cccs2)n1C +CCc1cc(C(=O)N2CCCc3ccccc32)no1 +C#CCNC(=O)C1CCN(S(=O)(=O)CCCC)CC1 +CCOC(=O)Nc1ccc(NC(=O)c2sccc2SC)cc1 +CC(C)NC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2 +O=C(NCCOCC(F)(F)F)N1CCCC2CCCC21 +CCOC(=O)c1[nH]c(C)c(C(=O)N(CC)c2ccccc2)c1C +CCCNS(=O)(=O)c1cc(C)c(Cl)cc1C +CC(Cc1ccco1)NC(=O)CN1C(=O)CCOc2ccccc21 +CNC(=O)NCC(=O)NCc1ccccc1Oc1cccc(C)c1 +CCC(CC)(CO)NC(=O)CSc1ccccc1C +CC(C)(C)OC(=O)NCCC(=O)NCc1cscn1 +O=C(c1ccc(Cl)cc1)N1CCOC(c2ccccc2)C1 +CC(=O)Nc1nnc(SC(C)Cc2ccc3ccccc3n2)s1 +Cn1ccnc1SCC(=O)N1CCC(C(N)=O)CC1 +O=C(Nc1ccccc1O)c1nnn(-c2ccc(F)cc2)n1 +O=C(Nc1ccc2c(c1)OCO2)N1CCN(c2ccccc2)CC1 +Cc1n[nH]cc1Nc1nn2cc(C(C)(C)C)nc2s1 +CCOC(=O)c1cnc2c(cnn2C)c1NCc1nccs1 +Cc1ocnc1C(=O)OCC(C#N)Cc1cccs1 +Cc1n[nH]cc1CNC(=O)C1Cc2ccccc2CN1 +Cc1ccc(-c2cccc(C(=O)N3CC(O)C3)c2)o1 +Cc1nnsc1C(=O)N=c1[nH]c2ccccc2s1 +COc1ccc2cc(CNC(=O)NC(C)C)ccc2c1 +Cc1cc(S(=O)(=O)NCC(C)N2CCOCC2C)sc1C +CC(NC(=O)COc1cccc2c1CCC2=O)c1ccco1 +Cc1ccc(C(=O)NC(C)C(=O)N2CCOCC2)cc1 +Cc1cc(C)n2c(SCC(=O)Nc3ccc(F)cc3)nnc2n1 +Cc1ccc(C(=O)Oc2cccc3ccccc23)cn1 +O=C(Cc1noc(C2CC3CCC2O3)n1)Nc1ccccc1 +CC(C(N)=O)n1ccnc1Cc1cccc(Br)c1 +CC(CCC(C)(C)C)NC(=O)c1scnc1C1CC1 +CN(CC1CCCO1)C(=O)Nc1cccc(OCCn2cccn2)c1 +N#Cc1cccc(OCC(=O)Nc2ccc(Br)cc2F)c1 +O=C(Nc1ccc2c(c1)OCO2)Nc1cnn(C2CCOCC2)c1 +Cc1ccc(NC(=O)CCNC(=O)Cc2ccccc2C)nc1 +COc1cccc(C(=O)Nc2cccc(-n3nnnc3C)c2)c1F +CCNC(=O)c1nsc(C(=O)NCc2ccccc2F)c1N +CN1CCN(C(=O)c2ccc(N3CCN(CCO)CC3)nc2)CC1 +CCc1c(C(=O)NCCCc2cn[nH]c2C)cnn1-c1ccccc1 +CC(C)C(C)N(Cc1ccco1)C(=O)c1cnc2ccccn2c1=O +COc1cccc(-c2nn(-c3ccccc3)cc2C(=O)NC2CC2)c1 +CC(Cc1ccccc1F)NC(=O)CN1CCCCC1=O +COc1ccc(CNC(=O)N2CCCC2)c(C(F)(F)F)c1 +COc1ccc(NC(=O)c2cccc(OCC(F)F)n2)cc1Cl +CCCNC(=O)CC(C#N)c1ccc(OC)c(C)c1 +CCCCn1c(=O)[nH]c2nc3cc(NC(C)=O)c(C)cc3nc2c1=O +N#CC1(N(Cc2ccccc2)Cc2ccccc2)COC1 +CN(C(C#N)c1ccccc1)S(=O)(=O)c1cccs1 +COc1ccc(-c2[nH]nc(C)c2-c2csc(C)n2)c(O)c1 +COC(=O)CN1CCN(c2cc(C)nc3ncnn23)CC1 +CCc1nc2nnc(C(=O)N3CCN(C)CC3)c(C)n2n1 +CCOc1ccccc1C(=O)NCC(=O)Nc1nc(CC)c(C)s1 +CCC(C)N(Cc1ccccc1Cl)C(=O)c1cccc(=O)[nH]1 +Cc1occc1CN(C)C(=O)C1CCC(=O)NC1 +CCc1noc(CC)c1CC(=O)Nc1ccc(F)c(F)c1F +N#CCCN(Cc1cccnc1)C(=O)CSc1ccncc1 +Fc1cc(Br)ccc1-c1nnc2sc(C3CC3)nn12 +COC(=O)c1nc(C(F)(F)F)cc(Cl)c1C(=O)OC +Cc1cccc(N2CCN(C(=O)CSc3nncs3)CC2)c1C +CC(=O)Nc1ccc(CC(=O)OCc2ccccc2F)cc1 +COc1ccc(Oc2ncnc(N(C)c3ccccc3)c2N)cc1 +NC(=O)Cn1cc(NC(=O)CC2CCc3ccccc3C2)cn1 +CCc1nnc(NC(=O)NC2CCC(C)CC2)s1 +O=C(Nc1ccccn1)C1CC(=O)N(Cc2ccccc2)C1 +Cc1cc(NC(=O)c2ccc(Cl)c3cccnc23)ccn1 +Cc1cc(NC(=O)N(CCO)C2CC2)ccc1-n1cnnn1 +COc1cc(C#N)ccc1OCCn1c(-c2ccccc2)noc1=O +CC(C(=O)N1CCCC1c1nc2ccccc2s1)n1cncn1 +Cn1ccnc1C(=O)N1CC2CCc3c(n[nH]c3C(F)(F)F)C2C1 +CN(Cc1ccc(F)cc1)C(=O)NCc1ccccn1 +COc1ccc(O)c(C(=O)c2cnc3cc4c(cc3c2)OCO4)c1 +CCC(NC(=O)NCCc1csc(C)n1)c1ccccc1OC +O=c1cc(C(F)(F)C(F)(F)F)[nH]n1-c1ccccc1 +COc1ccc(C2CC(C)N(C(=O)C3(C#N)CCC3)C2)cc1 +O=C1COc2c(cccc2-c2nc(-c3ccncc3)no2)N1 +CCOCCCNC(=O)Nc1cccc(C(=O)NC)c1C +O=C(CSc1ccc(F)cc1)OCc1nnnn1-c1ccccc1 +CC(C)COC(=O)N1CCC(C(=O)Nc2ccncc2)CC1 +O=C(Nc1nc2ccc(Cl)cn2n1)NC1CCc2ncnn2C1 +Cc1cc(C(N)=O)c(NC(=O)c2ccnc(OCC(F)F)c2)s1 +CCCNC(=O)C(C)NC(=O)Nc1ccc(Br)cc1C +Cc1ccc(NC(=O)CC(C)C(N)=O)cc1Br +Cc1nc(C)n(C2CCCN(C(=O)c3cc(F)cc4[nH]cnc34)C2)n1 +CCOC(=O)c1ccc(N2CCN(c3ccccc3O)CC2)nc1 +CC1CCCCC1OCCNC(=O)c1ccc(S(C)=O)cc1 +Cc1csc(CNC(=O)NCc2ccoc2)n1 +CC(C)(C)C(=O)NCC(O)c1ccc2c(c1)OCCO2 +CCOCCCNC(=O)Nn1cnc2ccccc21 +COc1cccc(CCC(=O)N(C)Cc2ccc(O)cc2)c1 +COCCNC(=O)c1nn2ccccc2c1Cl +CC1CCCc2sc3nc(SCC#N)n(N)c(=O)c3c21 +COc1ccc(C)cc1NC(=O)CSc1nc(=O)[nH]c(C)c1C#N +COC(=O)C1(CNC(=O)c2cc(C)no2)CCCCC1 +CC(C)c1nnc2n1CC(CNc1ncnc3c1cnn3C)CC2 +Cn1cc(CCC(=O)C(C#N)c2nc3ccccc3[nH]2)cn1 +COc1cccc(OCCNC(=O)NCC2CCCO2)c1 +COc1ccc(CN(C)C(=O)c2coc(-c3ccccc3)n2)cc1 +O=C(c1ccc[nH]1)N1CCC(Nc2cccnc2)CC1 +CSc1nnc(NC(=O)c2cc(C)nc3ccccc23)s1 +COc1ccccc1CNC(=O)CN1C(=O)COc2ccc(C)cc21 +C=CCc1ccc2[nH]c(C)c(C(=O)OCC)c(=O)c2c1 +COC(=O)CCCN1CCN(C(=O)Nc2cnccc2C)CC1 +O=C(NCc1cccc(C(F)(F)F)c1)NCc1nnc2ccccn12 +Cc1nnc2c(NCC3CCCO3)nc3ccccc3n12 +CCOC(=O)C1CCCN(C(=O)CCCc2c[nH]c3ccccc23)C1 +CC(=O)n1ccc2cc(O)c(Br)cc21 +CCOc1ncccc1C(=O)OCC(=O)NC1CC1 +CC(C)C1CNC(c2ccccc2)CN1S(C)(=O)=O +COc1cc(F)ccc1NC(=O)CCc1ccco1 +Cc1ccc(C(O)C(=O)Nc2c(C)cccc2C(C)C)c(C)c1 +Cc1[nH]c2ccccc2c1C(=O)C(C)OC(=O)c1nccnc1N +Cc1ncccc1C(=O)N(CC(F)(F)F)C(C)C(C)C +CCc1cc(N)c2oc(C(=O)N3CCOCC3)cc(=O)c2c1 +Cc1cccc(NC(=O)C2CCCc3ccccc32)n1 +O=C(C(c1cccnc1)N1CCOCC1)N1CCC(O)(CO)CC1 +COc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1 +COc1cc2c(c(CN(C)Cc3nccs3)c1)OC(C)C2 +COC(=O)c1ncc(Br)c2c(N)c(C)ccc12 +O=C(Cc1ccncc1)c1ccc(C(F)(F)F)cc1 +O=C(NCc1cc[nH]n1)c1ccc(-c2ccco2)[nH]c1=O +O=C(CSc1cccs1)Nc1ccccn1 +Cc1ccc(CN(C)C(=O)Cc2csc(N3CCCC3=O)n2)o1 +CN(C)C(=O)COc1cccc(CNC(=O)c2cccc(Cl)c2)c1 +CCCCn1c(SCc2noc(-c3ccc(C)cc3)n2)n[nH]c1=O +O=C(CSc1ccncc1)NCc1ccccc1OC1CCCC1 +Cc1cc(C)cc(NC(=O)NCc2nccc(N(C)C)n2)c1 +COc1ccc(COC(=O)CN)cc1Br +Cc1ccc(NC(=O)NC2CCCC2(C)CO)cc1Cl +Cc1ccc(C(=O)NCc2nc(-c3ccccc3)cs2)cc1 +O=C(NCC1CCC1)Nc1cccc(-n2cccn2)c1 +O=C(CSc1nnc(N2CCCC2)n1C1CC1)N1CCCCC1 +COC(=O)CCN(C)C(=O)Cc1c(Cl)cccc1Cl +COc1ccc(C(=O)NC(C)(C)C(=O)Nc2c(C)cccc2C)cc1 +CCN(CC(C)C#N)C(=O)CN1CCCc2ccccc21 +Cc1ccccc1NC(=O)Cn1nnc(-c2ccco2)n1 +N#Cc1ccsc1NC(=O)CCc1ncc(-c2ccccc2F)o1 +Cc1noc(C)c1S(=O)(=O)NCCc1ccc2c(c1)OCCO2 +COc1ccc(CC(=O)Nc2cc(F)cc(F)c2)cc1 +Cc1cc(C)cc(OCCNC(=O)Nc2nncs2)c1 +C=CCNC(=O)c1ccccc1NC(=O)CNC(=O)c1ccccc1 +Cc1oc(S(N)(=O)=O)cc1C(=O)NCc1csc(N(C)C)n1 +CCNS(=O)(=O)C1CCN(Cc2c(C)oc3ccccc23)C1 +COCC(C)NC(=O)C1CCN(c2nc3ccc(C)cc3s2)CC1 +CCn1cc(Cl)c(C(=O)N(C)Cc2cn(C)nc2C)n1 +c1ccc(C(CNCc2cccnc2)N2CCOCC2)cc1 +Cc1cnc(C(=O)N2CCCC(n3nc(C)nc3C)C2)cn1 +CC(C)c1nnc(-c2ccc(S(=O)(=O)Nc3ccccc3)o2)o1 +CSc1ccc(C(=O)NC2c3ccccc3CC2O)o1 +CC1CCC(C(C)C)C(NC(=O)c2nonc2N)C1 +COC(=O)CC1CCCCN1C(=O)c1cccn1C +OC1CCN(c2ncc3c(Br)ccn3n2)C1 +CC1COCC(C)N1CC(=O)N1CCCCCC1 +CCn1ccc2ccc(NC(=O)NCC(C)Cn3cccn3)cc21 +O=C(Cn1ccc2c(=O)[nH]ccc21)Nc1cccc(Br)c1 +Cc1csc(NC(=O)CC2CCCN(C(=O)NCC(C)C)C2)n1 +c1ccc(CSc2nnnn2-c2cccc3ccccc23)nc1 +O=C(NC1CCCC1)C1CCC2C(CCN2c2ncc(F)cn2)O1 +CCCC1CCCN(C(=O)c2cccc(OC)c2F)C1 +CSc1nnc(COc2ccc(N3CCCC3=O)cc2)s1 +CCOC(=O)CCn1nc(-c2cccnc2)c2c1CCNC2 +CSc1cccc(NC(=O)C2CN(C(=O)c3cc(C)on3)C2)c1 +CC1CCCCC1OCCN1CCOC(C)(C)C1 +CC(C)COCCC(=O)Nc1cnn(-c2ccccc2F)c1 +CC(=O)NCCSc1ccc(S(=O)(=O)N2CCCC2)cn1 +Cc1nc(CNc2ccc(C(=O)NC3CCCCC3)cc2)cs1 +CC(C)(C)c1noc(CCCC(=O)OC2CCCC2)n1 +COc1cccc2cc(C(=O)N3CCOCC3)c(=O)oc12 +CN(Cc1nccs1)C1CCN(c2ncccn2)CC1 +COC(=O)c1ccc(NC(=O)NCC(C)(C)c2ccncc2)cc1C +O=C(NCc1ccccc1-n1cccn1)NCC(O)c1cccs1 +O=c1[nH]c2ccccc2c(=O)n1CCC(O)c1ccccc1 +Cc1cnc(CNC(=O)C(CC(C)C)N2CCCCC2=O)s1 +O=C(Nc1cccc2cccnc12)c1n[nH]c2ccccc12 +COc1cc(NC(=O)c2csc(C)n2)c(OC)cc1Cl +COc1cccc(OCC2CCCN(C(=O)c3cnc(C)s3)C2)c1 +CCc1cc(C)c(C(=O)NCc2csc(=O)[nH]2)o1 +Cc1nnc(NC(=O)CSc2ccccn2)s1 +COc1nc(OC)nc(N2CCN(C(=O)OC(C)(C)C)CC2)n1 +C#CCNS(=O)(=O)c1ccc(C(=O)NCC)cc1 +COc1cc(-c2c(C)nn(CCC(N)=O)c2C)cc(C(F)(F)F)c1 +CCn1nnc2cc(C(=O)Nc3ccc(Cn4cncn4)cc3)ccc21 +CC(C)(C)CC(=O)N1CCC(C(=O)NCC(F)(F)F)CC1 +COc1ccc(C(=O)N2CCCC(n3nc(C)nc3C)C2)cn1 +N#Cc1ccc(C(=O)Nc2sc3c(c2C#N)CCC3)cc1 +COC(=O)c1cccc(Oc2ncnc3c2cnn3C)c1 +COc1cccc(NCC(O)c2ccc(Cl)c(N)c2)c1 +COC(=O)CCC(=O)c1cc(Cl)c(C)cc1C +CCC(C)CS(=O)(=O)NCc1cn(-c2ccccc2)nn1 +Cc1nc(Nc2ccc(Br)cc2)[nH]c(=O)c1CCO +CCOc1cc(C2NCCc3cccc(C)c32)ccc1O +CC(C)CC(=O)N(Cc1nnc(-c2ccccc2Cl)o1)C(C)C +Cc1ccc(S(C)(=O)=O)cc1C(=O)NC(C)(C)C +CCOc1ccc(CCC(=O)N2CC(C(N)=O)CCC2C)cc1 +CN1CCOC(C(=O)Nc2ccc3nc(-c4cccs4)[nH]c3c2)C1 +Cc1cc(-c2nnc(CN(c3ccc(F)cc3)C(C)C)o2)c(C)o1 +CCC(C)NC(=O)NC1CCCN(S(C)(=O)=O)C1 +Cc1ccc(-n2c(=O)[nH]cc(C(=O)Nc3ccccc3)c2=O)cc1C +CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(C)c(C)c2)CC1 +OCCN1CN(c2nccs2)CN(c2nccs2)C1 +CC(C)CNC(=O)N1CCCC(CC(=O)NCc2ccco2)C1 +O=C(Cc1coc(-c2ccccc2)n1)Nc1cccc(-c2ncc[nH]2)c1 +COc1cc2c(cc1Cl)C(c1nccs1)NCC2 +CCOCCCNS(=O)(=O)c1ccc2c(c1)CCCN2 +O=C(NCc1csc(=O)[nH]1)c1csc(C2CCCO2)n1 +CCNC(=O)NC1(C(=O)NCCc2ccc(C)cc2C)CCCC1 +C(=Cc1nn2c(-c3ccccc3)nnc2s1)c1ccco1 +NS(=O)(=O)NC(c1ccccc1F)C1CCCC1 +Cn1c(=NC(=O)c2ccco2)sc2cc3c(cc21)OCCO3 +COC(=O)C(c1cccc(C#N)c1)N1CCC(OC)CC1 +COCCn1nc(C)c(NCc2ccc(C)cc2)c1C +Cc1cc2ccccc2n1CC(=O)N(C)CC(C)C#N +Cc1cc(C)n(-c2nc(CCNC(=O)NC(C)(C)C)cs2)n1 +COc1cc(C(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)on1 +CCN(Cc1ccc(C(=O)OC)cc1)CC(C)C#N +CSc1ccccc1C(=O)OCc1nn2c(=O)cc(C)nc2s1 +O=C(N1CCOC2CCCCC21)C1(c2ccccc2)CC1 +Nc1nonc1-c1nnc(-c2ccc(O)c(F)c2)o1 +Cc1ccccc1CNc1ccc(CN2CCCC2=O)cc1 +CCC(C)c1ccc(NC(=O)CSc2nc(N)cc(=O)[nH]2)cc1 +Cc1ccc(C(C)NC(=O)NCC(=O)Nc2ccccc2)o1 +Cc1ccoc1C(=O)Nc1ccc(Br)cc1N +COC(=O)Cn1c(CNC(=O)c2cccc(C)c2)nc2ccccc21 +CC(C)CCC1CCCN(C(=O)NCc2ncn(C)n2)C1 +Cc1ccc(C(=O)Nc2ccccc2NC(=O)c2ccncc2F)cc1 +O=C(NCc1nnc2n1CCC2)NC1CCSc2ccccc21 +O=C(Nc1ccccc1OC(F)(F)F)c1ccc(F)nc1 +CNc1ccc(Cl)c(C(=O)Nc2ccccc2C)n1 +COc1ccc(C(C)(C)C)cc1NC(=O)CSc1nncn1C +COC(=O)c1n[nH]c(N)c1-c1cccc(Br)c1 +CC1(C)CCCN1C(=O)Cc1c(F)cccc1F +Cc1nc(C(=O)N(C)CC(=O)NC(C)C)cs1 +CCOCCOc1ccc(C2(C)Nc3ccccc3C(=O)N2C)cc1 +CC(O)CC(C)CNC(=O)NC1CCN(c2ccccc2)C1=O +Nc1ccccc1C(=O)N1CC2CC(C1)c1cccc(=O)n1C2 +COc1ccc(-c2cnn(-c3ccccc3)c2)nc1N +CC(C)C1C(=O)NCCN1C(=O)Cc1cccc(OCC#N)c1 +O=C(c1ccc(=O)[nH]c1)N1CCCCCC1c1ccncc1 +COC(=O)CCCc1ccc2c(c1)nc(C(C)C)n2C +Cc1csc(C2CN(Cc3nc4c(cnn4C)c(=O)[nH]3)CCO2)n1 +CCOC(=O)N1CCC(Nc2ncnc3ccsc23)CC1 +Cc1noc(C)c1C(=O)N1CCC(C)c2ccccc21 +Cc1nc(CSc2ncnc3sc(C)cc23)no1 +O=C(COC(=O)c1cccnc1)Nc1ccccc1 +CNC(=O)NC(C)(C)C(=O)NC(C)CCc1ccco1 +Cc1nc(NC(=O)c2ccc3c(c2)NC(=O)CS3)sc1C +CC(=O)c1ccccc1N(Cc1ccco1)C1CC1 +COc1ccc(CNC(=O)c2cnn(-c3ccncc3)c2C)cc1C +CCCc1nnc(NC(=O)Cn2ncc(=O)c3ccccc32)s1 +CCCc1nc(C2CC2)c(-c2nnc(NC)s2)s1 +CCOC(=O)C1CCN(C(=O)NCC2CC=CCC2)CC1 +CCN(C(=O)c1cccc(CCC(C)(C)O)c1)C1CCOC(C)(C)C1 +O=C(NCCc1cccs1)c1csc(Nc2ncccn2)n1 +Nc1nccnc1C(=O)NCC(=O)Nc1ccc(F)cc1 +Cc1cc(-c2nnn(-c3ccc(O)cc3)c2N)ccc1Cl +CC(Cn1ccnc1)NS(=O)(=O)c1ccc(F)c(Cl)c1 +C=C(C)CN1C(=O)C(CC)(CC)N(C)c2ccc(N)cc21 +CCc1cc(-c2c(C3CC3)n[nH]c2N)ccc1OC +CC1(C)CN(C(=O)CCc2cc(F)ccc2F)CCO1 +CCOc1cccc(CC2C(=O)Nc3ccccc32)c1OC +CC(=O)Nc1ccc(NC(=O)COc2ccccc2C#N)cc1 +Cc1cccc(OC(=O)CCNC(=O)c2ccsc2)c1 +CC(NC(=O)Cc1ccccc1)c1nc2ccccc2o1 +O=S(=O)(Cc1cccc(F)c1)NCC(O)c1ccoc1 +CC(C)(C)OC(=O)N1CCCN(C(=O)c2ccccn2)CC1 +CCN(C(=O)c1cc(OC)no1)c1ccccc1C +CCOC(=O)c1cnn(-c2nc(C)nc3sc4c(c23)CCC4)c1N +Cc1cc(N)nc(SC(C)C(=O)c2ccc3c(c2)CCC(=O)N3)n1 +NS(=O)(=O)c1ccnc(S(N)(=O)=O)c1OC1CC1 +CCCC(=O)Nc1cccc(C(=O)Nc2ccc(C(C)=O)cc2)c1 +COc1ccc(C)cc1C(C)NC(=O)c1ccc(C#N)cc1 +COc1ccc(CCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 +Cc1nn(C)c(-c2ccncc2)c1Br +COCCNC(=O)N1CCC(C(=O)Nc2cc(C)on2)CC1 +Cn1c(C(C)(C)C)nc2cc(NC(=O)c3ccncc3)ccc21 +O=C1COCC1CCc1ccccc1Br +CNC(C)C1NCCc2cc(Br)cc(F)c21 +Cc1cccc(NC(=O)c2cccc(S(=O)(=O)NC3CC3)c2)n1 +O=C(c1c[nH]nc1C1CCCCC1)N1CC(c2cccnc2)C1 +COc1ccc(C(NC(=O)c2ccncc2)C(F)(F)F)cc1 +Cc1cccnc1CNc1cccc(CS(=O)(=O)NC(C)(C)C)c1 +COc1ccccc1NC(=O)C#Cc1ccccc1 +O=c1[nH]c(-c2ccccc2Br)cn1CCO +CC(C)(C)Oc1cc(CNC(=O)CCc2nc[nH]n2)ccn1 +Fc1ccc(CN2CCOCC2C2CC2)c2ncccc12 +Cc1ccc(C(=O)Nc2ccccc2Cn2cccn2)cc1 +COC(=O)c1c(C)nn(Cc2cc(F)cc3cccnc23)c1C +CC(=O)Nc1ccc(Cl)c(NC(=O)N2CCc3sccc3C2)c1 +OCc1c(-c2cccs2)nc2ccc(Br)cn12 +CCc1nnc(C2CCN(C(=O)NCCc3ccccc3)CC2)s1 +CC(C(=O)Nc1ccc(Cl)cc1)n1nc(-c2ccco2)oc1=O +CCC(C)N(Cc1ccncc1)C(=O)c1c(F)cc(OC)cc1F +O=S(=O)(c1ccc2c(c1)CCC2)N1CCOCC1 +Cc1nc(CNc2ncc(Br)cn2)n[nH]1 +Cc1nc(NC(=O)CSc2nnc(C3CC3)n2C)sc1C +CCn1cnnc1CNC(=O)Nc1ccc(Cn2cccn2)cc1 +CC(NC(=O)N1Cc2ccccc2-c2ccccc2C1)c1nncn1C +Cc1cc(NC(=O)c2cc(C)n(C(C)c3ccccc3)c2C)n(C)n1 +CC(=O)NC(C)C(=O)OC(C)c1cc(F)ccc1F +O=S(=O)(NCc1ccc2c(c1)CCO2)c1ccccc1 +Cn1cnnc1CCC(=O)N1CCN(Cc2ccc(Cl)cc2)CC1 +CN(CC(=O)N1CCNC(=O)C1)Cc1c(F)cccc1Cl +COCCCNC(=O)Cn1c(C2CCCO2)nc2ccccc21 +COc1ccc(CCC(=O)NCc2ccc3c(c2)OCO3)cc1N +COC(=O)N(C)c1ccc(NC(=O)CSc2ccccc2)cc1 +CCC1CCCN(C(=O)NC(C)c2ccc3c(c2)NC(=O)CO3)C1 +O=C(NCCNC(=O)C1CCCC1)c1cn(-c2ccc(F)cc2)nn1 +CS(=O)(=O)N1CCCC2(CC(Oc3cccnc3)CO2)C1 +CC(=O)c1ccc(NC(=O)CSc2ccc(F)cc2)cc1 +O=C(c1cccnc1)n1c(COc2ccccc2)nc2ccccc21 +CC(C(=O)N(C)CCOc1cccc(Cl)c1)n1cncn1 +Cc1cc(NC(=O)c2onc(S(C)(=O)=O)c2N)no1 +CCCn1c(C)nnc1SCC(=O)Nc1c(C)n[nH]c1C +CC(CO)NC(=O)Nc1cccc(-c2nccs2)c1 +CCN(C(=O)c1cc2c([nH]c1=O)CCCC2=O)c1ccc(F)cc1 +CCn1c(CC2CCN(C(=O)Cc3ccncc3)CC2)nn(C)c1=O +CCn1ccc(C(=O)Nc2cc(-c3ccsc3)no2)n1 +CCC(C)(C)NS(=O)(=O)c1ccc(OC)c(NC(C)=O)c1 +Cc1cc(OC(=O)CCc2c(C)nc3ncnn3c2C)ccc1Cl +Cc1cc(C)c(NC(=O)Nc2ccccc2)c(C)c1 +Cc1nc2cc(NC(=O)c3cccnc3OCC(F)F)ccc2o1 +O=C(Nc1c(F)cc(F)cc1Br)C1CCCO1 +Cc1noc(C)c1C(=O)N1CCCC(c2nc3ccccc3[nH]2)C1 +Cc1nc(C(=O)OCc2ccc3c(c2)OCO3)c2ccccn12 +COc1ccccc1-c1cc2ncc3c(n2n1)CC1CCC3N1C(C)=O +CCOC(=O)c1cn(-c2ccc(F)cc2)c(C(=O)OCC)c1N +COc1ccc(COC(=O)c2sc(C)cc2OC)cc1OC +N#CCCn1c(-c2ccccc2)nc2cccc(F)c21 +COc1cc(OC)cc(C(=O)NCC(=O)Nc2ccc(C)cc2C)c1 +CCOC1CCCN(C(=O)c2cc3ccccc3c(OC)n2)C1 +CC(=O)c1ccc2c(c1)N(CC(=O)N(C)C1CCCCC1)CC(C)O2 +OCc1nnn(Cc2c(F)cccc2Cl)c1-c1ccccc1 +CNC(=O)CN1CCOC2CN(C(=O)CC3CCCC3)CC21 +CCOC(=O)c1ncn(-c2cccc(OC)c2)c1N +O=C(c1cc(Cl)ccn1)N1CCc2cc(F)ccc2C1 +Cc1cccc(NC(=O)N2CCC3(CC2)OCCCO3)c1 +O=C(Cn1nnc2ccccc2c1=O)OCc1cccc(F)c1F +CCc1nnc(SCC(=O)N2CCc3ccccc3C2)n1N +COc1cc(F)ccc1N1CCN(Cc2cccnc2C)CC1 +O=C(NC1CC1)C1CCCN1C(=O)Nc1ccccc1 +CC(C(=O)N(C)c1ccccc1)n1nc(-c2ccccc2)ccc1=O +C=CCN(Cc1ccccc1)C(=O)Nc1ccc2c(c1)OCC(=O)N2 +Cc1cc(N)n(C(=O)c2ccc(N3CCOCC3)cc2)n1 +CN(C)C(=O)C1CCN(S(C)(=O)=O)c2cc(Cl)ccc2O1 +CN(Cc1ccc(F)cc1)C(=O)c1cc2ccccn2n1 +CC(C)(C)OC(=O)N1CCC2(CC1)CCN(Cc1ccccc1)C2=O +NC(=O)c1n[nH]c2ccc(NC(=O)c3cccc(-n4cnnn4)c3)cc12 +O=C(NC1CC1)c1nc(COc2ccc3c(c2)N=C(O)CC3)no1 +c1ccc(COc2ccc(-c3nc[nH]n3)cc2)cc1 +Cc1cc(-c2nnc(NC(=O)c3ccccc3Cl)o2)c(C)o1 +CCOc1ccc(NS(=O)(=O)c2cccc(C(C)=O)c2)cc1 +Cn1cc(NC(=O)c2cccnc2OCC(F)F)cc(Cl)c1=O +Cc1nc(NC(=O)c2sc(C)nc2C)n(C)n1 +O=C(c1n[nH]c2ccccc12)N1CCCC1CC(O)c1ccccc1 +CCc1onc(C)c1C(=O)NCCC(=O)Nc1cccnc1 +CN(C)c1ccc(-c2nc3ccc(N)cn3n2)cc1 +Cc1c(C(=O)NC(C)C2CCCO2)cnn1-c1ccc(F)cc1F +O=C(CN1CCCS1(=O)=O)Nc1ccc2c(c1)COC2 +Cc1cc(NC(=O)Cn2cnnn2)ccc1C(=O)N(C)C +CCNC(=O)Cc1csc(SCC(=O)c2ccc(F)cc2)n1 +CC(C)C(CNC(=O)CCc1ccc2c(c1)OCO2)N1CCOCC1 +CCn1cnnc1CNC(=O)C1CC(=O)N(c2cccc(Cl)c2)C1 +O=C(CCOCC(F)(F)F)Nc1ccc2c(c1)NC(=O)CS2 +COc1cc(OC)cc(C(=O)NCc2nccc(N3CCCC3)n2)c1 +Cc1ccc(NC(=O)CSc2nnnn2-c2cccc(F)c2)cc1 +Cc1n[nH]c(CCC(=O)N2CCN(c3cnn(C)c(=O)c3)CC2)c1C +CC(c1ccncn1)N(C)C(=O)c1cccc(C#CC(C)(C)O)c1 +COc1ccccc1OCC(=O)Nc1ccc2c(c1)N(C(C)=O)CC2 +CC1(C)CN(C(=O)c2cccs2)C(c2ccccc2)CN1 +Cc1ncc(C(C)NC2CCCN(c3cccc(F)c3)C2)s1 +CN(Cc1nc2ccccc2[nH]1)S(=O)(=O)c1ccccc1 +CCC(NC(=O)NCc1cc(F)cc(OC)c1)c1noc(C)n1 +CCOCCC(=O)N1CCN(c2ccccc2OC)CC1 +CC(C)(C)CC(=O)Nc1nc2ccc(N)cc2s1 +Cc1n[nH]c(O)c1C(c1ccc(F)cc1)c1c(O)n[nH]c1C +CC(C)n1cnc2ccc(NC(=O)C3CC(=O)OC3(C)C)cc2c1=O +CCOCCN(CC)C(=O)c1cnn(-c2ccncc2)c1C +CCSc1nnc(SCC(C#N)CCC#N)s1 +CC(C)c1noc(C(C)Nc2cnn(C(C)C)c2)n1 +CS(=O)(=O)NCCNC(=O)C(N)Cc1ccccc1 +Cc1nc(-c2ccc(CNC(=O)c3ccc(F)cc3F)cc2)cs1 +CN(Cc1ccccc1)C(=O)c1scnc1C1CC1 +COc1cccc(C2C(C(N)=O)C(C)=Nc3nc(CCCO)nn32)c1 +COC(=O)c1cc(-c2ccc(OC)c(OC)c2)nn1-c1ccccn1 +CC(C)n1nnnc1SCc1ccc(F)cc1Cl +O=C(CCSc1ccccc1F)Nc1ccc2c(c1)OCO2 +CC1CCN(C(=O)CSc2ncccc2N)CC1 +CCn1cnnc1CNC(=O)Cn1c(C)c(C)sc1=O +Cc1ccc(CNC(=O)c2nnc(Cc3ccccc3Cl)o2)cc1 +CCc1cccc(C)c1NC(=O)CNc1ccccc1 +c1cc2c(cc1CSc1nnc(C3CC3)n1C1CC1)OCO2 +O=C(Nc1nc[nH]n1)c1ccc(Br)cc1O +O=C(c1cnc(N2CCOCC2)nc1)N1CCOCC1 +Cc1nnc(NC(=O)NCCN(C(=O)OC(C)(C)C)C2CC2)s1 +CN1CCN(C(=O)c2ccc(=O)[nH]c2)c2nc3ccccc3nc21 +CCOc1cc(F)ccc1NC(=O)Cc1cccc2cccnc12 +CCOc1ccc(NC(=O)c2cccn2-c2cccnc2)cc1 +COc1ccccc1CC(=O)Nc1ccc(-n2cncn2)cc1 +CC(c1ccccc1F)N(C)C(=O)c1cccc(-c2nnco2)c1 +Cn1nnnc1SCCC(=O)Oc1ccc(C(C)(C)C)cc1 +CCOc1ccc(NC(=O)CCc2nc(C)no2)cc1F +Cc1cc(CNC(=O)CN2CCOc3ccccc32)ccc1F +Cc1oc(C)c(C(=O)N2CCOC(C)(C)C2)c1Br +CC1CC(N2CCN(C(=O)c3ccc(F)cc3F)CC2)C(=O)O1 +CCCn1ccnc1SCC(=O)Nc1cccc(Cl)c1 +O=C(Cc1cc2ccccc2[nH]c1=O)OC1CCCc2ccccc21 +O=C(CSc1nnnn1Cc1cccs1)NCc1ccco1 +Cc1nnc(SC(C)C(=O)NC2CCCC2)n1Cc1ccccc1 +CCc1ncc(C(=O)N(CC)Cc2cc(Cl)ccc2OC)cn1 +CC(C)C(=O)Nc1nc2cc3c(cc2s1)OCCO3 +Cc1onc(-c2ccccc2Cl)c1C(=O)NC(C)C1CCCO1 +CC(C)CN(Cc1ccsc1)C(=O)C1C=CC=N1 +Cc1cccc(CNCC(O)c2ccccc2)c1F +Cn1ccc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)n1 +CC(CCCO)NC(=O)Nc1ccc(F)c(C#N)c1 +CC(NC(=O)NCc1ccc2c(c1)CCO2)c1cnn(C)c1 +COC(=O)CSc1nc2cc(C)c(C)cc2[nH]1 +N#Cc1ccccc1COc1cccc(C(=O)N2CCC(O)CC2)c1 +CC(C)(C)NC(=O)C1CN(C(=O)OC(C)(C)C)CCN1 +CCNC(=O)CN(CC)C(=O)NCc1cn(-c2ccccc2)nn1 +O=C(NCCS(=O)(=O)NCC1CCC1)c1ccccn1 +O=C(CNC(=O)Nc1c(F)cc(F)cc1-c1ccccc1)NC1CC1 +Nc1ccc2c(c1)nc(C1CC1)n2C1(c2ccccc2)CC1 +O=C(CNc1ccc(Cl)c(F)c1)N1CCc2ccccc2C1 +Cc1nc(NC(=O)c2ccc(N3CCOCC3)nn2)sc1C +COc1ccc(OC)c(NC(=O)CN2CCOc3cc(F)ccc32)c1 +Cc1cc(S(=O)(=O)Nc2ccc3c(c2)CCC3)c(C)s1 +CC(NC(=O)c1cc(N)cc(S(C)(=O)=O)c1)C(N)=O +O=C1CCCN1c1cccc(OCc2nc(-c3cccs3)no2)c1 +CCN1CCN(C2CCN(C(C(N)=O)c3ccccc3)CC2)C1=O +Nc1ccc2nc(CCC(=O)N3CCCC3)cn2c1 +CCc1noc(C)c1C(=O)OCc1ccc(-n2cccn2)cc1 +C=CCN(Cc1cccs1)S(=O)(=O)c1cccc(C#N)c1 +CC(C)CCn1cccc1CN1CCC(NS(C)(=O)=O)C1 +Cc1ccc(-c2noc(-c3nnn(CC(N)=O)c3N)n2)cc1 +CC(CNS(=O)(=O)N(C)CC1CC1)N1CCc2sccc2C1 +CC(C#N)Sc1nc2ccsc2c(=O)n1C +COc1ccc(F)cc1NC(=O)N1CC(CO)OCC1C +CNC(=O)c1nc(C(=O)NCc2ccc(F)cc2Cl)cs1 +O=C(COC(=O)c1ccccc1)NCCc1ccccc1 +Cc1nnc(SCc2cc(=O)n3c(C)cccc3n2)n1C1CC1 +CCC(=O)Nc1ccc2c(c1)C(=O)N(C)c1ccccc1O2 +COc1ccc(OC)c(C(O)CNc2ccccc2)c1 +CN(Cc1ccccc1)C(=O)c1ccc(CSc2ncn[nH]2)cc1 +O=C(NC1CCCCC1)c1cn(-c2cccc(Cl)c2)nn1 +CC(=O)c1c(NC(=O)c2ccccc2)nc(C)nc1-c1ccccc1 +CCS(=O)(=O)Nc1ccc(-c2noc(-c3ccc(F)cc3)n2)cc1 +CCc1nsc(N2CCN(Cc3ccc(OC)cc3OC)CC2)n1 +CCOCc1ccc(CNC(=O)c2cnn(C)c2)cc1 +CCCOCCC(=O)Nc1cc(C)c(C)cc1N +Cc1ccc(C(=O)N2CCCC2C(=O)Nc2ccccc2C)cc1 +O=C(Cc1ccc2c(c1)CCC2)N1CCc2ncc(Cl)cc2C1 +Cc1cc(C(=O)Nc2cccc(COc3ccc(CC#N)cc3)c2)[nH]n1 +CCc1ccc2c(c1)C(CCNC(=O)c1sccc1C)C(=O)N2 +O=C(NCCC(O)c1ccco1)c1ccc(Cl)cc1Cl +CC(Sc1ccc2ccccc2n1)C(=O)N1CCOCC1 +O=C(c1cccc(CO)n1)N1CCCCC1CCc1cccs1 +CC(C)CNC(=O)c1ccccc1NC(=O)C1CC(=O)N(C)C1 +CC(=O)N1CCN(CC(=O)c2c(N)n(C)c(=O)n(C)c2=O)CC1 +Cc1cccn2cc(C(=O)N3CCC4(CC3)OCCO4)nc12 +CC1(NC(=O)COc2ccc(Br)cc2F)CCC1 +CC1CCN(C(=O)c2cccc(C(F)(F)F)c2)C(C)C1 +Cc1ccc(C(=O)NC2CCN(C(=O)c3ccoc3)CC2)c(C)n1 +O=C(NCCN1CCOCC1)NCC(F)(F)F +CCCN(CC(=O)N(C)C)c1ccc(Cl)cc1C#N +CCC(NC(=O)C1Oc2ccccc2O1)c1ccc(F)cc1 +CCN(CC)c1nc2nonc2nc1N1CCOCC1 +O=C(C1CC1)N1CCC2C(CCCN2C(=O)c2ccc(F)cc2)C1 +COc1ccc(Cl)cc1C(=O)NC(C)c1c(C)nn(C)c1C +CNC(=O)c1ccc(OC)c(NCC(=O)Nc2ccc(Cl)cc2)c1 +COc1cc(Br)cc(C)c1NC(=O)CNC(C)=O +O=C(NCCCOCC1CCOCC1)Nc1ccc(F)c(Cl)c1 +CC(=O)OCc1nc(-c2ccccc2)c2ccsc2n1 +Cc1ccc(-n2nc(CO)c(C(=O)NCCC3=CCCCC3)n2)cc1 +COCC(C)NC(=O)CCCc1nc2ccccc2c(=O)[nH]1 +COc1ccccc1NC(=O)CCc1ccccc1 +COc1ccc(C(=O)Nc2cc(C)ccn2)cc1OC +Cc1noc(C)c1COc1ccc(C(=O)Nc2ccccc2N)cc1 +O=C1c2cc(Cl)ccc2-n2c1nc1ccccc1c2=O +CCCc1nnsc1C(=O)N1CCCC1c1nc(C)no1 +Cc1cccc(NC(=O)N2CCCN(C(=O)c3ccncc3)CC2)c1 +COc1c(Cl)ccc2c1C(c1ccc(O)cc1)NCC2 +Cc1cc(OCCN2CCC(=O)CC2)ccc1Cl +CCc1onc(C)c1NC(=O)NCC(=O)NCc1ccco1 +COc1ccc(NC(=O)C23CC4CC(CC(C4)C2)C3)cc1NC(C)=O +CCOCCN(CC)C(=O)C1(c2ccc(F)cc2F)CCOCC1 +CCNC(=O)N1CCN(C(=O)COc2ccccc2C(C)CC)CC1 +CCCC1CN(C(=O)Nc2cc(C(=O)NC3CC3)ccc2C)CCO1 +COCCn1c(N)c(C(=O)CN2CCc3ccccc32)c(=O)[nH]c1=O +COCCN1CC(C(=O)Oc2ccc(C#N)cc2Cl)CC1=O +COc1ccc(C(=O)Nc2ccccc2N2CCCC2)cc1 +CCNC(=O)CN1CCN(C(=O)c2cc(C)n(C(C)C)c2C)CC1 +CC(C)Oc1ccc(-c2nc(C(=O)NC(C)C(N)=O)cs2)cc1 +NC(=O)CNC(=O)C1CCCN(C(=O)NC2CC2)C1 +CCn1ccc2cc(NC(=O)CN(C)c3cnccn3)ccc21 +Nc1c(NCCc2ccccc2)ncnc1N1CCCCC1 +CC(CNc1nccc(C(F)(F)F)n1)N1CCOCC1C +COc1ccc(F)cc1NC(=O)CCC1CCCOC1 +COc1ccc(C(=O)Nc2cc(C)on2)cc1-c1ccccc1 +C=CCN1C(=O)C(O)(C2CCc3ccccc3C2=O)c2ccccc21 +CCSc1ccccc1C(=O)N(CC(F)(F)F)C1CCOCC1 +Cn1ccnc1-c1ccc(F)c(C(=O)NC2CCCC2)c1 +CC(=O)Nc1cccc(NCC(=O)N(C)Cc2ccccc2C)c1 +N#Cc1cccc(NCC(=O)c2cc(F)ccc2F)c1 +COc1ncccc1C(=O)NCC#CCOc1ccc2c(c1)OCO2 +CCn1cc(NC(=O)NCCc2ccc(F)cc2)cn1 +Cc1ccc(CC(=O)OCc2nc(N)nc(N)n2)cc1C +CCC(C)NC(=O)C1CCN(Cc2nc3ccccc3[nH]2)CC1 +CCN(C(=O)Nc1cnn(CC(N)=O)c1)C1CC1 +CCS(=O)(=O)N1CCC(NC(=O)NCC2CCC2)CC1 +CNc1ccc(Cl)c(C(=O)N2CCC(OC)CC2)n1 +O=S(=O)(c1ccccc1)c1ccc(NC2CC2)nn1 +O=C(Cc1ccc(F)cc1)Nc1cc(-c2cccs2)no1 +N#Cc1cc(NC(=O)c2ccc(OCC3CC3)nc2)ccc1F +CCC1CN(C(=O)c2ccc(C#N)nc2)CCN1C(C)C +COc1ccccc1NC(=O)c1ccc(-c2csnn2)cc1 +Cc1nnsc1C(=O)N1CCC(Oc2ncccc2Cl)CC1 +CC1(C(=O)N2CCC(O)CC2)Cc2ccccc2C(=O)O1 +CCNS(=O)(=O)c1cnn(C2CCCC2)c1N +CC(=O)Nc1cccc(C(=O)NCc2ccc3c(c2)OCO3)c1 +C#CCN(CC(=O)Nc1nccs1)Cc1ccc(F)cc1 +CC(C)N(CC(N)=O)C(=O)c1ccc(Br)cc1 +COc1ccc(C(C)(C)CNC(=O)c2ccn(C)c(=O)c2)cc1OC +Cn1c(Cn2ccnc2)nnc1C1CCN(C(=O)C2CCC2)CC1 +O=C(OCCO)c1cc(-c2cccs2)nn1-c1ccccc1 +CCC(C)C(C)NC(=O)c1cc(OC)c(OC)cc1OC +O=C(NCCC1=CCCCC1)NCC1COc2ccccc2O1 +CCn1cc(C(=O)N2CCN(C(=O)c3cc(C)oc3C)CC2)cn1 +CC(OCC1CCCO1)C(=O)Nc1ccc(F)c(F)c1 +Cc1ccn2c(=NC(=O)CCCc3ccccn3)[nH]nc2c1 +O=C(Nc1ccc(OC(F)F)c(Cl)c1)c1cnccn1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)c1ccccc1C +CC(C)NC(=O)CCCNC(=O)c1n[nH]c2cc(Cl)ccc12 +CCN(CC)C(=O)CSc1nc2c(c(C)c1C#N)CCC2 +CCn1c(SCc2nnc(C)o2)nnc1-c1ccccc1OC +OCc1cnc(SCc2cccc(F)c2)n1CC1CCCO1 +COCc1ccc(CNC(=O)Nc2cnn(-c3ccccc3)c2)cc1 +Cc1cccc(C(C)C)c1NCC(=O)c1cccc(N)c1 +Cc1ccccc1C(=O)N1CC(c2nc(-c3cccnc3)no2)C1 +CC(C)(C)OC(=O)N1CCC(c2ccccc2)C(O)C1 +O=S(=O)(c1ccc(O)cc1)N(CCO)C1CCCC1 +Cc1ccncc1NC(=O)Nc1cccc(COC(C)C)c1C +CCOC(=O)CNC(=O)Nc1ncc(-c2ccccc2)n1C +CC1Cc2ccccc2N1C(=O)COc1ccc(C(N)=O)cc1 +Cc1ccc(N)cc1NC(=O)C(C)Oc1ccccc1Br +COc1cccc(C(=O)Nc2ccc(S(=O)(=O)NC(C)C)cc2)c1 +CN(C)C(=O)CNC(=O)C1(c2cccc(Cl)c2)CCC1 +CCN(C)C(=O)c1cccc(OC(=O)C2CCOc3ccccc32)c1 +CC(=O)NCC(=O)Nc1ccccc1OCC(C)C +CCc1cccc(C)c1NC(=O)COC(=O)Cc1ccc(F)cc1 +CC(C)(CO)NC(=O)CCOc1ccc2c(c1)OCO2 +Cn1c(CNC(=O)c2cn3cccnc3n2)nc2ccccc21 +CCCC(CC)NS(=O)(=O)c1ccc(N)cc1F +OCc1cn(-c2ccc(NCCc3cccs3)cc2)nn1 +CCCCNC(=O)C(NC1=NS(=O)(=O)c2ccccc21)C(C)C +CCOc1c(CCC(=O)N2CCN(C)CC2)cc(N)cc1OC +Cc1ccc2ncc(C(=O)N(C)Cc3ccccc3Cl)n2c1 +CCN(CC1CN(Cc2ccn(C)c(=O)c2)CCO1)c1cccnn1 +Cn1cc(C2CC(O)=Nc3c2cnn3Cc2ccccc2)cn1 +COCCN(CC(=O)N(C)C)C(=O)c1ccc(C(F)(F)F)cc1 +CCCCC(CC)C(=O)Nc1nc(C)c(C(=O)N(C)C)s1 +Cc1nc(-c2nnc(NC(=O)NC(C)C)o2)cs1 +Cc1ccccc1CNc1cnn(CC(F)(F)F)c1 +COc1ccc(Cl)cc1NC(=O)c1nccnc1CO +Cc1cc(NC(=O)c2ccnn2C)c2ccccc2n1 +Cc1occc1-c1nnc(SCCOC(C)C)n1N +CN(C)Cc1c(O)c(=O)cc(CO)n1CCCO +CC1Cc2ccccc2N1C(=O)CSc1nncn1C +CN(C)S(=O)(=O)NCC1CC(=O)N(c2ccc(Cl)cc2)C1 +Cc1ccccc1C(=O)Nc1ccc(Br)cn1 +CCc1c(-c2ccc(Br)cc2)n[nH]c1NC(=O)COC +C=CCn1c(N)nnc1SCc1cccc(Br)c1 +CC(CC#N)NC(=O)c1c(Cl)c2ccccc2n1C +NC(=O)CSc1nc(N)c(NC(=O)c2cccs2)c(=O)[nH]1 +Cc1ccc(NC(=O)c2ccc(CNC(=O)NC(C)C)cc2)cc1F +CCC1CCCC(NC(=O)NC2CCN(C(=O)c3ccoc3)CC2)C1 +N#Cc1cnn2ccn(Cc3cc(Cl)cc(Cl)c3)c12 +COC(=O)c1ccc(NC(=O)N2CCCC(C)C2CO)cc1Cl +COC(=O)c1cccc(NC(=O)N(C)CC2CC2)c1 +Cc1ccc(SC(C)C(=O)NCC2CCCO2)c(C)c1 +COc1ccc(Br)cc1C(=O)Nc1nc(C)cs1 +CCN(CC)C(=O)CC(c1ccco1)c1ccccc1OC +O=C(CCc1ccsc1)N1CCCc2ccccc21 +Cc1ccccc1OCCNC(=O)Nc1cccnc1 +N#CCCN(CCC#N)C(=O)c1sc2ccccc2c1Cl +CC(=O)NCC(Cc1cccc(F)c1)n1cccc1 +CSc1ccc(C(O)CNC(=O)c2cn(C)nn2)cc1 +CCOC(=O)CN(C1=NS(=O)(=O)c2ccccc21)c1ccccc1 +CCCn1c(C)cc(C)c(-c2csc(NCC)n2)c1=O +O=C(NCCNc1ncccn1)C1(c2ccc(F)cc2)CCCC1 +CC(C)C(=O)Nc1ccc(C(=O)N(C(C)C)C2CCOCC2)cc1 +CC(C)(C)C1CCN(S(=O)(=O)N2CCC3(CCC3)C2)CC1 +CN1CCN(S(=O)(=O)c2cc(C(F)(F)F)ccc2F)CC1 +Cc1noc(CCCSc2nc3ccc(Cl)cc3[nH]2)n1 +Nc1nonc1C(=O)NCc1cccc(Cl)c1 +COC(=O)C1C(=O)NCC1c1ccc(Cl)cc1 +Cc1nn(C)c2nc(NCCN3CCCC3=O)sc12 +CN(CC(=O)NC1CC1)C(=O)Cc1ccccc1N +COCC(O)CN(C)S(=O)(=O)N1CCCC(C)C1 +CC(CNc1ncnc2ccsc12)CN1CCCC1=O +Cc1ccccc1CN1CCC(c2nc(-c3ccncc3)no2)C1 +CCS(=O)(=O)NC(c1ccc(OC)cc1)C(C)C +COc1ccc(Nc2ncc(N)cc2C)cc1OC +Cc1cc(NC(=O)NC2CCOC2c2ccc(Cl)cc2)c[nH]c1=O +Cc1cnc(NC(=O)c2ccc3c(c2)NC(=O)CS3)s1 +CCc1cc(NS(=O)(=O)c2cc(C)c(F)cc2Cl)n(C)n1 +CCNC(=O)CNC(=O)NCc1cc(F)ccc1Br +CCOc1ccc(C(=O)Nc2cc(-c3ccncc3)n[nH]2)cc1 +CC(C)Oc1cccc2c1CCNC2c1ccnnc1 +O=C(CSc1nnnn1-c1ccccc1Cl)N1CCCC1 +CCCOc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1 +CN(C)c1ccc(C(=O)Nc2nnc(Cc3ccccc3)o2)cc1 +O=C(CCN(CC1CC1)CC(F)(F)F)N1CCCCC1 +COc1cc(C(=O)N2CCC(CC(N)=O)CC2)cc(OC)c1C +CC(=O)NCCNc1ccc(CN2CCOCC2)cc1 +CCOc1cc2c(cc1Cn1cnc3c(cnn3C)c1=O)OC(C)C2 +Fc1ccc(Cc2nc(-c3ccc4nncn4c3)no2)cc1 +Cc1noc(C)c1CN1CCN(C(=O)COc2ccccc2F)CC1 +CC1(C)CN(C(=O)c2ccc(-n3ccnc3)nc2)CCO1 +CCS(=O)(=O)c1ccccc1NCc1nc(C)no1 +CCc1ccccc1NC(=O)CS(=O)(=O)c1ccc(F)cc1 +CCC(=O)N(C)c1ccccc1C(=O)N(C)Cc1ccccn1 +Cc1ccc(Cc2nnc(NC(=O)N(C)Cc3ccoc3)s2)cc1 +CC(CCNC(=O)NCc1ccc(S(C)=O)cc1)c1ccccc1 +Fc1ccc(C2CCCN2CCCN2CCOCC2)cc1 +NC(=O)c1ccc(N2CCCC2)c(NC(=O)c2cnccn2)c1 +O=C(Cc1ccc(Cl)cc1)NCc1cn2ccccc2n1 +CCCC(=O)Nc1ccc(C(=O)N2CCC(C(=O)NC)CC2)cc1 +Cc1cc2cc(CNC(=O)C(C)Oc3ccccc3)ccc2[nH]1 +O=C(CCC(=O)N1CCN(c2ccccc2O)CC1)c1ccccc1 +CC(Oc1ccc(C#N)cc1)C(=O)Nc1sccc1C#N +CC(C)n1c(=O)[nH]c2cc(C(=O)NCC3CCOC3)ccc2c1=O +Cc1ccc(-n2cnnc2SCC(=O)NCC2CCCOC2)cc1 +COCCCNc1nc2ccccc2n2c(C)ncc12 +COc1ccccc1-n1nnnc1SCc1ccccn1 +N#Cc1ccc(OCCOc2ccc3c(c2)OCO3)cc1 +O=C(Nc1ccccn1)c1cc2cc(Br)ccc2oc1=O +CN(CC(=O)NC(C)(C)c1ccc2c(c1)OCCO2)S(C)(=O)=O +COCCNC(=O)c1nc(-c2ccc(N3CCOCC3)cc2)no1 +Cc1ccc(SCCCN(C)C(=O)c2cnc(C3CC3)nc2)cc1 +COC(=O)c1ccc2c(c1)CCN2C(=O)c1ccc(-n2cccn2)cc1 +CCc1noc(CC)c1CNC(=O)C1CSc2ccccc21 +CCOC(=O)c1cn(C2=NCCN2C(C)=O)c2ccc(OC)cc12 +Cc1nnc(CSc2nnc(COc3ccc(Cl)cc3)[nH]2)o1 +C#Cc1cccc(NC(=O)c2ccccc2Br)c1 +O=C(NCc1ccc2c(c1)OCO2)Nc1cccc(-c2nnco2)c1 +COCc1ccc(C(=O)Oc2ccc(-n3cnnn3)cc2)cc1 +O=C(Nc1ccc(Cl)c(F)c1)NC1C2CCC(C2)C1CO +COC(=O)C1(N(C)C(=O)c2ccc(F)c(C)c2)CCCCC1 +Cc1cc(C(=O)NCc2nnc3n2CCCCC3)c(C)o1 +COc1ccc(S(=O)(=O)Nc2ccc3c(c2)CCO3)cc1OC +O=C(NC1CCC(C(F)(F)F)CC1)c1cccc(-c2ncn[nH]2)c1 +O=C(NCCC(=O)N(Cc1ccco1)C1CC1)C1CCCC1 +O=C(NCCCn1cnc2ccccc21)C1CCCO1 +O=C(CCNC(=O)c1cccs1)OCC1CC1 +CSc1nnc(N2CCOCC2)n1Cc1ccccc1 +Cc1cc(C(=O)NCCc2ccc(F)cc2F)c(C)n1C1CC1 +Cn1c(C(=O)NCCn2cccn2)cc2ccc(Cl)cc21 +Cc1cc2occ(CC(=O)OC3CCOC3=O)c2cc1C(C)C +COc1cccc(OC2CN(Cc3ccnn3-c3ccccc3)C2)c1 +N#CCCN(CCC(F)(F)F)Cc1ccc(Cl)c(F)c1 +CCc1noc(CS(=O)(=O)c2ccc(O)cc2)n1 +CC(C)(C)NC(=O)Cn1cccc(S(=O)(=O)N2CCCC2)c1=O +CCc1nc(CC(=O)NCc2nnc3n2CCC3)cs1 +CC(C)c1cnc(-c2ccc(NC(=O)C3CCOCC3)cc2)o1 +CNC(=O)c1cccc(C(=O)Nc2cc(F)c(OC)cc2OC)c1 +c1ccc(-n2nnnc2SCc2nc(-c3cccs3)no2)cc1 +COc1ccc(CNCCc2nc(-c3ccco3)n[nH]2)cc1 +O=C(NCC1(O)CCc2ccccc21)Nc1ccc(Cl)cc1 +Cc1ccc(C(=O)CCC(=O)NCC(O)c2ccc(F)cc2)cc1 +O=C(C1CC=CC1)N1CCCC2(CCN(c3cncnc3)C2=O)C1 +CCn1nc(C)cc1C(=O)NCC(=O)Nc1cccc2ccccc12 +C=CCNC(=O)CCc1nc(-c2cccs2)no1 +O=C1CCc2cc(NC(=O)c3cc[nH]n3)ccc2N1 +Cn1c(C(=O)NCc2ncc[nH]2)cc2cc(C(F)(F)F)ccc21 +Cc1cccc(CN(C(=O)C2CC(=O)Nc3ccccc32)C2CC2)c1 +O=C(Cn1cc(NC(=O)c2ccccc2Cl)cn1)NC1CCCC1 +O=C(c1ccoc1)N1CCN(C(=O)c2cc(Cl)c[nH]2)CC1 +CC(=O)Nc1ccc(F)c(C(=O)NCCNC(=O)c2cccnc2)c1 +Cc1c(C(=O)N2CCOC(C)C2)sc2ccccc12 +O=C1CC(C2NCCc3ccc(-c4ccccn4)cc32)C1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)NCCCN1CCCC1=O)O2 +O=C(CCCO)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +CCC(C)OCC(=O)N(C)Cc1ccc(O)cc1 +Cc1csc(CN2CCN(C(=O)c3ccc(Cl)cc3)CC2)n1 +CC(NC(=O)C1CC(=O)OC12CCCCC2)c1nncn1C +COCCCNC(=O)C(N)c1ccc(C#N)cc1F +Cc1ccc(OCc2cc(=O)n3nc(C)sc3n2)cc1 +O=C(Nc1ccn(Cc2ccncc2)n1)c1[nH]ncc1Br +CCOC(=O)CNC(=O)N1CCCC1c1cc(C)on1 +CCCc1ccc(S(=O)(=O)NCC(O)c2sccc2C)cc1 +Cc1cc(F)ccc1S(=O)(=O)NCC(O)(c1ccccc1)C1CC1 +Cc1cccc(C)c1-n1nnnc1SCC(=O)c1ccc[nH]1 +Cc1cc(C)n(-c2ccc(C(=O)NCC(C)(C)c3ccncc3)cn2)n1 +CC(Oc1cccc2ccccc12)C(=O)Nc1ccccc1C(N)=O +COc1ccc(CCCC(=O)Nc2nccn(C)c2=O)cc1 +Cc1cc(C(=O)Nc2nnc(-c3ccsc3)o2)nn1C +Cc1ccc(C(=O)Cn2cnc3c(C)cccc3c2=O)c(C)c1 +Cc1ccc(NCCn2cnc3c2c(=O)n(C)c(=O)n3C)c(Cl)c1 +Cc1cc(C)c(NC(=O)N2CCC(OCC(C)C)CC2)c(C)c1 +NC(=O)c1ccc(NCc2cnn3ccccc23)cc1 +CN(Cc1cc(-c2cccnc2)no1)C(=O)COCc1ccccc1 +NC(=O)c1sc2nc(-c3cccnc3)cc(C(F)(F)F)c2c1N +CC(C)N1CCC(NC(=O)c2ccc(OCC(F)F)nc2)C1=O +COc1ccc(Cl)c(NC(=O)NCC(C)(C)C(N)=O)c1 +COC(=O)C(C)NS(=O)(=O)Cc1ccccc1 +c1ccc(C2COC(c3ccc4c(c3)OCO4)O2)cc1 +CC(C)CNS(=O)(=O)c1cc(S(C)(=O)=O)ccc1N +CNc1snc(C)c1C(=O)N1CCN(c2ccccc2F)CC1 +COc1ccc(CNC(=O)c2ccc(=O)n(-c3ccccc3)n2)cc1 +COC(=O)CCC(=O)Nc1ccn(CC(N)=O)n1 +CCc1ccc(C(C)NCC(=O)Nc2cc(C)on2)cc1 +CC(C)NS(=O)(=O)c1ccc(NC(=O)C2CCCC2)cc1 +O=C(NCc1cccs1)c1coc(NC(=O)c2cnccn2)n1 +CCc1ccc(C(=O)Nc2c(C)cc(-n3cnnc3)cc2C)cc1 +Nc1cnc(Nc2cccc(C(F)(F)F)c2)nc1 +C=CCc1ccccc1OC(=O)Cn1c(C)c(C)sc1=O +COc1ccc2c(c1)OCC(CNC(=O)NC(C)(C)C)C2 +Cc1cc(COc2ccc3c(C)cc(=O)oc3c2)no1 +Cc1nc(NC(=O)NCc2cccc(C(F)(F)F)c2)nn1C +CC(=O)NCC(=O)NCC(=O)N(C)Cc1ccc(C)s1 +O=C(c1ccc2cccc(O)c2n1)N1CCCCCC1 +O=C(NCc1cccnc1)c1nc(-c2cnccn2)no1 +CCC(C)Cn1c(C2CC(=O)N(CC)C2)nc2ccccc21 +Cc1noc(CCNC(=O)C(C)Oc2cccc(C(C)(C)C)c2)n1 +O=C(NCc1nnc2n1CCCC2)c1cccnc1OCC(F)F +CCCN1C(=O)C(C)(C(=O)NCc2cccs2)Oc2cccnc21 +N#Cc1cccc(CNC2C(c3ccccc3)CC(O)C2O)c1 +O=C(Nc1cccc(O)c1)c1ccc(Cl)cc1-n1cnnn1 +CCOC1CCN(C(=O)NC(C)Cc2cccc(Cl)c2)CC1 +CCC(=O)c1c(C)nc2n(CCN3CCOCC3)c3ccccc3n12 +CCN(CC)c1ncc(CN2CCC(C(=O)NC(C)C)CC2)s1 +NC(=O)c1ccccc1NC(=O)C1CNc2ccccc2O1 +CCc1ccc2nc(SCC(=O)N3CCOCC3)c(C#N)cc2c1 +CCC1COCCN1C(=O)Nc1cc(F)ccc1OC +OCCc1nnc(Cc2ccc(Cl)cc2Cl)o1 +Cc1cccc2c1C(NC(=O)c1ccccc1)CNC2 +CC1CCCC(CNc2cccc(C(=O)NCCO)c2)C1 +COC(=O)C1CC(O)CN1Cc1ccc(F)c(C(F)(F)F)c1 +COc1cc(N)ccc1NC(=O)CCOCC1CC1 +COc1cccc(CNC(=O)CNC(=O)Cc2ccccc2)c1 +COc1cc(C)c(-c2cc(=O)c(C#N)c[nH]2)cc1C +O=C(COc1ccc(NC(=O)C2CC2)cn1)NC1CC1 +COCC(C)(O)CNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +Cc1ccc(CC(=O)N(C)CCc2ccccc2)cn1 +COc1ccc2[nH]cc(CC(=O)NC3(C#N)CCCCC3)c2c1 +Cc1c(Cl)cc(NC(=O)NCc2ncn(C)n2)cc1Cl +CC(Cn1cccn1)NC(=O)N1CCN(c2ccc(O)cc2)CC1 +CCOc1ccc(NS(=O)(=O)c2cccc(C#N)c2)cc1 +C=CCc1cc(CNC(=O)c2cnn(C)c2C)cc(OC)c1OC +COc1ccc(-c2cc(C(=O)NCc3ccc(C)o3)no2)cc1 +CC(Oc1ccc(Br)cc1)C(=O)NCc1ccccn1 +CCc1ccccc1N1CC(C(=O)NC2CCC(C)CC2)CC1=O +Cn1cc(C(=O)NCc2ccc3[nH]c(=O)[nH]c3c2)cn1 +Cc1cncc(C(=O)N2CCC(O)C2Cc2cccnc2)c1 +O=C(C1CCCC1)N1CCC(n2nc(-c3cccs3)oc2=O)CC1 +CC(=O)Nc1ccc(C(=O)OC(C)c2ccccc2)cc1 +COc1cccc(-c2nc(CSc3nccn3C)cs2)c1OC +Cn1cccc1CNC(=O)CCCc1nnc2ccccn12 +CCC(C)NC(=O)CCNC(=O)Nc1c(F)cccc1F +COc1ccc(CNC(=O)CCCO)cc1C(C)C +CC(NC(N)=O)C(=O)NC(c1ccc(F)cc1)C1CCCC1 +O=C(Cc1noc2ccccc12)OCc1nnnn1-c1ccccc1 +CCOC(=O)Cn1nc(C)c2c1N=C(O)CC2c1c(C)nn(C)c1C +COC(=O)N(C)c1ccc(NC(=O)Cc2ccc(C)c(OC)c2)cc1 +COc1ccnc(NC(=O)C(C)OC2CCCCCC2)c1 +Cc1oc(-c2ccccc2)nc1CC(=O)N(C)Cc1cccs1 +CCC(CCO)NC(=O)Nc1cccc(S(=O)(=O)C(F)F)c1 +CNC(=O)c1ccc(CN(C)C(=O)c2cc3ccccc3s2)cc1 +CC(CO)NC(=O)CSc1nncn1C1CC1 +O=C(COc1ccc(F)cc1Cl)NCCc1nc2ccccc2[nH]1 +Cc1ccc2cc(C(=O)N(C)CCOCC3CC3)c(C)nc2c1 +CCCNc1nnc(S(=O)(=O)CC(=O)NC2CC2)s1 +COCCN(Cc1ccsc1)C(=O)c1c[nH]nc1C1CCCCC1 +Cc1ccc(NC(=O)c2cc(N)cnc2C)c(Br)c1 +N#Cc1ccc(C(=O)N(CCc2cccs2)C2CC2)cc1 +CCOC(=O)C1N=C(c2cccc(Cl)c2)OC1=O +O=C(CSc1nnnn1-c1cccc(F)c1)Nc1cccc(F)c1 +O=C(Cn1[nH]c(=O)ccc1=O)Nc1cccc(-n2cnnn2)c1 +O=C(Cn1nc2c3ccccc3ncn2c1=O)Nc1ccc(F)cc1 +CCN(C)C(=O)CN(CCc1ccccc1)C(C)=O +CCCc1noc(CCCC(=O)Nc2ccn(C)n2)n1 +Cc1ccc(C)c(S(=O)(=O)Oc2ccccc2C#N)c1 +O=C(Nc1nc[nH]n1)c1ccc(Br)cc1Cl +CCc1nnc(NC(=O)NC2(C)Cc3ccccc3C2)s1 +Cn1cc(C(=O)Nc2cccc(-c3ccc4c(c3)CCO4)c2)ccc1=O +COc1cccc(-c2[nH]ncc2C(=O)NC2CCc3ccccc32)c1 +COC(=O)N1CCC(CNC(=O)c2ccc(Cl)c(Cl)c2)CC1 +CCOc1ccc(OCCCn2cnc3ccccc3c2=O)cc1 +Cc1n[nH]c2ncc(C(=O)NCC3(C)CCCC3)cc12 +Nc1cccc(C(=O)OCC(=O)Nc2ccncc2)c1 +O=C(Nc1cccc(NC(=O)c2cccnc2)c1)c1cccnc1 +COc1ccc(N(C)C(=O)c2ccnc(OC3CCC3)c2)cc1F +COC(=O)c1cnn2c1NCN(Cc1ccco1)C2 +Cc1noc(C)c1-c1ccc(S(=O)(=O)NCc2cccs2)cc1 +CC(=O)Nc1ccc(NC(=O)c2nccc3cccc(N)c23)cc1 +CCCNS(=O)(=O)c1ccc2c(c1)CCCN2C(C)=O +O=C(Nc1ccc(F)cc1)N1CCn2cnnc2C1 +CCOC(=O)c1[nH]c(C)c(C(=O)Nc2cccc(C(C)=O)c2)c1C +CC(=O)c1ccc(Oc2ccc(C(=O)Nc3nncs3)cc2)cc1 +COC(=O)CCc1cc(Cl)c(OC)cc1OC +Cc1ccc(=NS(=O)(=O)c2ccc3c(c2)OCCCO3)[nH]c1 +COc1ccc(OC(=O)c2ccc(OCC(F)F)nc2)cc1F +COc1ccc(N2C(=O)C(C)(C)CS2(=O)=O)c(OC)c1 +Fc1ccc(NCc2nc(-c3ccco3)no2)cc1 +Cc1nn(C)c(C)c1CC(=O)OCC1CC=CCC1 +O=C(c1cccc(-n2cccc2)c1)N1CCOc2ccccc21 +CCOc1ccc(CNC(=O)c2cc(-c3cccnc3)[nH]n2)cc1 +O=C(CCc1ccccc1)OCC(=O)N1CCCCCC1 +O=C1NCCCc2[nH]c(-c3ccc(F)c(F)c3F)nc21 +O=S(=O)(NCc1cn[nH]c1)c1ccc(Cl)c(C(F)(F)F)c1 +CC(C)c1ccccc1NC(=O)CCNC(=O)c1ccccc1 +COCCOc1ccc(NC(=O)NC(C)c2ccc(C)o2)cn1 +Cc1ccc(Cc2nnc(NC(=O)Cc3cccs3)o2)cc1C +Cc1nnc2c(SCC(=O)N3CCCCC3)nc3ccccc3n12 +CC(C)(C)OC(=O)NC1CN(c2ccncn2)C1 +CC(=O)NC1CCN(C(=O)c2c(F)cccc2Cl)CC1 +COc1ccc(C(O)C(C)NC(=O)c2csnn2)cc1 +CCn1c(CCNC(=O)c2cccc(C#N)c2)nc2cccnc21 +CCN(CC(=O)NC)c1ccc(C(N)=O)cc1N +COc1ccc(CC(C)N(C)C(=O)Cc2c(C)nn(C)c2C)cc1 +O=C(CN1CCCC1=O)Nc1ccccc1CN1CCc2ccccc21 +NC(=O)C1(CNC(=O)c2n[nH]c(=O)c3ccccc23)CCOCC1 +Cc1cccc(NC(=O)NCCNC(=O)c2ccc(O)cc2)c1C +CCCC1CN(C(=O)C2CCC(F)(F)CC2)CCO1 +Cc1nc(C(C)(C)NC(=O)Nc2ccccc2Cl)no1 +COc1cc(C(=O)NCc2ccc(F)cc2)ccc1N +CCOC(C)c1nc(CN(C)C2CC(C)OC2=O)cs1 +COc1ccc(NC(=O)c2cn(C(C)(C)C)c3ncccc23)cc1 +COCC(=O)Nc1nc(C)c(SCC(N)=O)s1 +CCCCCc1nnc(NC(=O)CNC(=O)NC)s1 +COCCC1(O)CCN(C(=O)Cn2ccccc2=O)CC1C +CCN1C(=O)CCC12CCCN(C(=O)c1cnc(C)cn1)C2 +COC(=O)CSc1nnc2c(C)cc3cc(C)ccc3n12 +COc1ccc(CNC(=O)c2c[nH]nc2-c2ccccc2F)cc1 +CC(C)(C)C(=O)NC1CCS(=O)(=O)c2ccccc21 +O=C(c1ccc(=O)n(-c2ccccc2)c1)N1CCCCC1 +Cc1noc(C)c1CCC(=O)NCC#CCOc1ccc(F)cc1F +COc1cccc(CNC(=O)c2cnc3ccoc3c2)c1 +CC(C)c1cc(NC(=O)COc2ccc(F)cc2)[nH]n1 +Cc1nsc(N2CCN(Cc3cccc(C)c3C)CC2)n1 +Cc1cc(NC(=O)Cn2cnc3sc(C)c(C)c3c2=O)no1 +CN(C)C(=O)c1ccc(C(=O)Nc2ccc(N3CCCC3)nc2)cc1 +COc1ccc(CCN2CN=C(NS(C)(=O)=O)NC2)cc1 +CC(C)OCc1cccc(NC(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +CC(C)c1cccc(NCc2cnc(N3CCOCC3)nc2)c1 +Cc1c(NC(C)c2nnc(CC(C)C)o2)cnn1-c1ccccc1F +CCCS(=O)(=O)NC(C)C(=O)N1CCC(CO)C1 +CC(C)c1cc(NC(=O)c2cc(C(C)(C)C)nn2C)[nH]n1 +CS(=O)(=O)N1CCC(c2nccnc2-c2cn[nH]c2)CC1 +COc1ccc(NC(=O)CC(C)(O)C(F)(F)F)c(OC)c1 +O=C(Cc1c[nH]c2ccccc12)Oc1ccc(NC(=O)C2CC2)cc1 +Cc1nnc(SCC(=O)NCCc2c(F)cccc2F)s1 +Cc1nscc1C(=O)OCCN1CCCCCC1=O +CCOC(=O)C1(N)CC1c1ccc(C(C)(C)C)cc1 +CC(C)NC(=O)C1CCN(S(=O)(=O)c2cccnc2)CC1 +Cc1c[nH]nc1C1CCCN(S(=O)(=O)N2CCOCC2)C1 +CSc1ccccc1NC(=O)NCC1CCCCO1 +Cc1nc(CC(=O)NCC(O)c2cc3ccccc3s2)cs1 +CN(Cc1ccccc1Cl)C(=O)c1n[nH]c(=O)c2ccccc12 +CC(=O)Nc1cccc(C(=O)N(C)c2ccc(F)c(F)c2)c1 +C#Cc1cccc(NC(=O)N2CCN(CC(O)c3ccccc3)CC2)c1 +CCCCC1C=CCN1C(=O)c1cc(-c2ccc(O)cc2)n[nH]1 +COc1c(C)cnc(COc2cccc(C(C)=O)c2)c1C +O=C(CNc1ccc(N2CCCC2=O)cc1)NCCc1cccs1 +COc1ccc(C)cc1CCNc1cn[nH]c(=O)c1Cl +Cc1nc(C)c(C(=O)NCCNC(=O)COc2ccccc2)s1 +O=C(NCc1cccc(NC(=O)C2CC2)c1)c1ccccc1F +CCN1CCOC(C(=O)Nc2cc(C)cc3cccnc23)C1 +Cc1ccn(C)c(=O)c1NC(=O)N1CCN(Cc2ccccn2)CC1 +O=C(NCc1ccco1)c1ccc(Cl)c2cccnc12 +CCc1ccc(O)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1 +Cc1ccc(CCC(=O)N(C)CCc2ccncc2)cc1N +CCc1n[nH]c(SC(C)C(=O)Nc2cc(C)cc(C)c2)n1 +CN(C)c1ccc(-c2noc(CCNC(=O)c3cccs3)n2)cc1 +O=C(OCc1csc2ccccc12)c1cccnc1-n1cncn1 +Cc1nc(CNc2c(C)cc(Br)cc2C)cs1 +CCOCC(O)CN1CCN(C(=O)Cc2ccc(C#N)cc2)CC1 +Cc1n[nH]cc1NC(=O)Cc1c(C)nn(C(F)F)c1C +CCOCCn1c(C(C)NC(=O)c2ccco2)nc2ccccc21 +COC(=O)c1ccc2c(=O)[nH]c(-c3cnccn3)nc2c1 +Cc1noc(C(C)NC(=O)Nc2ccc(OC(C)C)cc2C)n1 +Cc1cc(-c2nnc(SCc3c(F)cccc3Cl)o2)nn1C +COc1ccc(CCC(C)NC(=O)NCc2nc(C)cs2)cc1 +CCCCn1nnnc1SCC(=O)N1C(C)CCCC1C +CCC(CC)C(=O)Nc1ccc(Oc2cccnc2)nc1 +Nc1cc2ccccc2nc1C1CCN(C(=O)c2cccnc2)CC1 +O=C(Nc1cc[nH]n1)c1ccc(S(=O)(=O)C(F)F)cc1 +N#Cc1cccc(CN2C(=O)COc3ccccc32)c1 +Cc1cc(C)c(C(=O)Nc2cccnc2C)c(C)c1 +COC(=O)CC(NC(=O)C1CCCC1)c1ccccc1Cl +COC(=O)C(NC(=O)c1cnn(-c2ccncc2)c1C)C(C)(C)C +O=S(=O)(c1cc(Cl)ccc1Cl)N1CCCC(O)C1 +Cc1cc(C)n2nc(C)c(C(=O)Oc3ccc4ccncc4c3)c2n1 +CCN(Cc1cccc(NC(=O)Cc2ccc(C)s2)c1)C(C)=O +CCCN1C(=O)CCc2cc(NC(=O)c3cc4ccccc4[nH]3)ccc21 +Cc1ccc(C(C)NC(=O)CSc2nccn2C)cc1 +OC1CCN(Cc2ccncc2)C1Cc1ccncc1 +Cc1nn(CC(=O)NCCN2CCOCC2)c(=O)c2ccccc12 +Cc1ccc(C(C)NC(=O)C(C)OCC2CCCO2)o1 +Cc1cccc(OCC(C)NC(=O)Nc2ccccn2)c1 +CCn1cnnc1CNC(=O)Nc1ccc(C(=O)NCC(C)C)cc1 +O=C(Oc1ccc2c(c1)CCC2)c1cnc(C2CCCO2)s1 +O=c1[nH]c2c(n1-c1ccc(Br)cc1)COC2 +CCOC(=O)c1cnc2c(ccc3ncccc32)c1OCC +CCNC(=O)C(Cc1cccc(N)c1)c1ccccc1F +Cc1cc(C)c(NC(=O)c2ccc(Cl)cc2N)c(C)c1 +CCc1onc(C)c1NC(=O)CCCc1nc2ccccc2c(=O)[nH]1 +CCc1n[nH]c(C2CCCN2C(=O)NCc2ccc(F)cc2)n1 +COCc1cccc(CNC(=O)C2CCCCN2S(C)(=O)=O)c1 +CS(=O)(=O)NCCNC(=O)C1COc2ccccc2C1 +c1ccc(-c2noc(C3COc4ccccc4C3)n2)nc1 +CC(C)c1ccc(OCC(=O)NCC(O)c2ccsc2)cc1 +COC(=O)c1ccc(CCNC(=O)c2occc2C)cc1 +O=C(NCC(O)Cc1ccccc1)c1ccsc1 +Nc1c(-c2ccccc2)nnn1-c1ccc(Cl)cc1 +Cc1nnc2ccc(NCC3CC34CCc3ccccc34)nn12 +Cc1noc(-c2cccc(=O)n2CC(=O)NCc2ccc(F)cc2)n1 +CCc1nn(CCC(C)O)c(=O)c2cc3sc(C)cc3n12 +O=S(=O)(Cc1ccccc1Cl)c1ncccc1Cl +COc1cccc(N2CCN(C3=NC(Cl)=NC4=NC=NC43)CC2)c1 +CCOC(=O)c1ccc(NC(=O)Cn2ccnc2)cc1 +CC(C)NC(=O)N1CCN(C(=O)N(C)C)CC2(CC(=O)N(C)C2)C1 +COCCC(=O)N1CCCCC1c1ncc(-c2cccc(F)c2)[nH]1 +O=C(NC1CCN(c2ccccc2F)C1=O)c1ccncc1F +CC(C)(C)NC(=O)Cn1nc(-c2ccccc2)oc1=O +CCCC1CN(C(=O)c2ccc3cc[nH]c3c2)CCO1 +CC(Nc1cccc(OCC(N)=O)c1)C(=O)NC(C)(C)C +Cn1nccc1C(=O)Nc1cc(-c2cccs2)nn1CCO +CC(C)N(C(=O)c1ccc(NC(=O)c2ccco2)s1)C1CCC1 +CCCC1CN(C(=O)c2c[nH]c(C)cc2=O)CC1NS(C)(=O)=O +CCOC(=O)CN(CC)C(=O)c1n[nH]c(=O)c2ccccc12 +COc1ccc(C(=O)NC(C(=O)Nc2cccc(F)c2)C(C)C)cc1 +COc1ncccc1CNC(=O)c1nc(-c2ccccc2)oc1C1CC1 +O=c1[nH]c2c(cnn2Cc2ccccc2)c(=O)n1-c1ccccc1 +CC1CCCCN1C(=O)c1ccc2ccccc2n1 +CCn1c(Cn2cccn2)nc2cc(NC(=O)c3ccco3)ccc21 +CCNC(=O)c1c(C)nc(N)nc1-c1ccccc1 +CCc1nc(CN(C)CCc2ccc(F)cc2)cs1 +CCC(OC)C(=O)Nc1ncc(Cc2ccccc2)s1 +CCOC(C)c1noc(CSc2nnnn2C)n1 +CC(C)NC(=O)c1ccc(NCCOc2ccc(C#N)cc2)cc1 +CCN(CC)C(=O)CCC(=O)NC1CC1C1CCCCC1 +N#Cc1cccnc1N1CCN(S(=O)(=O)c2ccccc2)CC1 +COc1cccc(C(=O)NC(C)c2ccc(-n3cccn3)cc2)c1F +O=C(NCCc1ccccc1)N1Cc2cncnc2C1 +CC(C)c1nc(CC(=O)NCc2ccc3c(c2)OCO3)cs1 +O=C(c1ccccc1)c1ccc(N2CCOCC2)cc1O +CC(C)CNC(=O)c1cc2c(=O)n3ccccc3nc2n1C +COC(=O)C1=C(c2ccccc2)N(C)C(=O)NC1c1ccco1 +COC(=O)Nc1cccc(OCC(=O)N(C)CC(F)(F)F)c1 +CC1CCC(C(N)=O)CN1C(=O)c1cc(-c2ccc(F)cc2)[nH]n1 +O=C(C1=NC=C(c2csc(N3CCCCC3)n2)C1)N1CCCC1 +COc1ccc(CC(=O)NCc2nn(C)c3ccccc23)cc1OC +CCCCS(=O)(=O)NCC(=O)N1CCc2c(F)ccc(F)c2C1 +COC(=O)c1ccc2nc(-c3ccccc3O)nn2c1 +Cn1cc(CCC(=O)Nc2n[nH]c(-c3cccc4ccccc34)n2)cn1 +O=C(CSc1nc(=O)[nH]c2c1CCC2)NCc1cccs1 +CC(=O)c1cnc(NC(=O)CCC(=O)c2ccc(F)c(F)c2)s1 +O=C(CCn1cncn1)N1CCN(C(=O)c2cccc(F)c2)CC1 +COCCn1cnnc1C(C)n1ccnc1-c1cc2ccccc2o1 +COc1cc(OC)cc(C(=O)Nc2ccc3c(c2)CC(=O)N3C)c1 +CC(O)CNc1ncc(Br)c2cc(F)cc(F)c12 +COc1cccc(CNC(=O)N2CCC(O)CC2)c1 +Cc1cc(=O)n(CC(=O)Nc2cccc(C)c2C)c(N)n1 +CCc1cc(NCc2c[nH]nc2-c2ccc(OC)cc2)n2nccc2n1 +NC(=O)C1CCN(C(=O)c2cc(Cl)c3c(c2)OCO3)C1 +CSc1nc(C(=O)Nc2ccc(F)c(C#N)c2)c2ccccn12 +O=C(NCc1ccccn1)C1CC(=O)N(c2ccc(F)c(Cl)c2)C1 +COc1ccc(C(C)NC(=O)c2cc(C)nc3c2cnn3C)cc1 +O=C(Nc1nc[nH]n1)c1cncc(Br)c1 +O=c1c2cccnc2ccn1Cc1nc(-c2ccccc2Cl)no1 +Nc1c(-c2ccccc2)noc1C(=O)NC1CCCC1 +CC(NC(=O)CSc1ccc2c(c1)OCCCO2)c1cccs1 +COc1ccc(C)cc1-n1nnnc1SCCc1ccccn1 +COCCN(CC(=O)N(C)C)C(=O)c1cc2c(s1)CCCC2 +CC(NC(=O)Cc1ccc(N2CCCC2=O)cc1)c1cccc(F)c1 +CN(C)c1c(Cl)cccc1NC(=O)CCc1ccco1 +CCc1nc(C)c2c(C)c(C(=O)NCC3CCCO3)sc2n1 +Fc1cc2ncnc(N3CCCC34CCCCC4)c2cc1F +CC(C)CNC(=O)C(C)Oc1ccc(N)cc1F +COc1ccc(N2C(=O)c3sccc3S2(=O)=O)cc1 +O=C(NCCc1ccccn1)c1cccc2ccccc12 +O=C(CC1COCCN1C(=O)c1cc2c(s1)CCC2)c1ccco1 +Cc1ccc(CNC(=O)NCc2ncc(-c3ccccc3)o2)cc1 +CSc1ccc(C(=O)OCC2CCC(=O)N2)cc1 +CCC(OC(=O)c1cccs1)C(=O)NCc1ccccc1 +CC(C)c1n[nH]c(C2CN(C(=O)CC3CCCO3)CCO2)n1 +CC(=O)c1csc(NC(=O)Cc2c[nH]c3c(C)cccc23)n1 +CN(C)C(=O)Cc1ccc(NC(=O)c2c(F)cccc2Cl)cc1 +Cc1ccc(-c2nnc(SCC(=O)Nc3cc(C)no3)n2C)cc1 +CC(=O)NC1CC(c2ccccc2)OC(c2ccccc2)C1 +COc1ccc2[nH]cc(CCNC(=O)C3CCCO3)c2c1 +CC(C)c1cc(NC(=O)c2cnc(Cc3ccccc3)s2)[nH]n1 +CC(=O)NC(C(=O)NCc1ccccc1)C1CCCC1 +Cc1cc(S(=O)(=O)N(C)C(C)(C)C#N)ccc1F +CC(C)COc1cccc(CCC(O)c2ccccn2)c1 +CC(C)N1CCOC2CN(C(=O)c3cccn3C)CC21 +Cc1cc(C(=O)N2CCOc3ccncc32)c(C)cc1Br +N#Cc1ccc(OCC(=O)N2CCCc3c(C(N)=O)cccc32)cc1 +O=C(OC1CCCC1)C1CCCN1C(=O)c1ccco1 +CC(c1ccc(F)c(F)c1)N(C)S(=O)(=O)c1cnn(C)c1 +CC(=O)OCCn1c(C)cc(=O)n2c3ccccc3nc12 +Cc1cc(C)n2nc(CNC(=O)c3ccccc3C)nc2n1 +Cn1cc(C(=O)NCc2cccc(NC(=O)Nc3ccccc3)c2)cn1 +CCCNC(=O)c1cc2c([nH]c1=O)CC(C)CC2=O +Cn1nc(C(C)(C)C)cc1C(=O)NCCOc1ccccc1 +COCCNc1nc2c(OC)c(OC)c(OC)cc2s1 +CC(C)n1cc(C(=O)N(CC(=O)NC(C)(C)C)C2CCCCC2)cn1 +Cc1cc(C)n2nc(CNS(=O)(=O)c3ccc(F)c(C)c3)nc2n1 +CC(=O)c1ccc(F)cc1NCC(=O)N1CC(C)OC(C)C1 +N#Cc1ccc(NC(=O)c2cc(C3CC3)on2)cc1 +CCC1(CC)C(NC(=O)N2CCC(n3cncn3)CC2)CC1OC +CC(O)c1cc(Cl)ccc1OC1CCCC1O +O=C(NCCc1nc(Cc2ccccc2Cl)no1)c1ccco1 +Cn1nccc1C(=O)NCC1(Cc2ccccc2)CCC1 +CCC(C)OC(=O)Cn1nc(C#N)cc1-c1ccco1 +CC(=O)c1ccc(S(=O)(=O)NC2CCC(C)CC2)cc1 +COc1ccccc1NC(=O)CCCNC(C)=O +CCCC(=O)NCCC(O)c1cccc2ccccc12 +COc1ccccc1C(C)NC(=O)c1cc(-c2cccnc2)on1 +COc1ncccc1CNC(=O)N1CCc2ccccc21 +C=CCOCCCC(=O)N1CC(C)Sc2ccccc21 +CCOC(=O)c1sc(C(C)NC(=O)NCC(C)C)nc1C +CC(OC(=O)c1ccc(=O)[nH]c1)c1ccc(F)cc1F +CCCNC(=O)CNS(=O)(=O)c1cnc(NC)nc1 +O=C(Cc1ccc(F)cc1)NCC1CCN(c2cnccn2)CC1 +COC(=O)c1c(NC(=O)C2CCCO2)sc2c1CCCCC2 +CCSc1ccc(C(=O)Nc2c(C)nn(C(C)C)c2C)cn1 +Cc1n[nH]cc1CN1CCN(c2ccnc(N(C)C)n2)CC1 +CCN(Cc1cccc(C)c1)C(=O)C(C)NC(=O)c1cccs1 +Cc1cccc(OC(=O)CCc2nc(-c3cccnc3)no2)c1 +CCNC(=O)c1ccc(C)c(NC(=O)NCc2ncn(C)n2)c1 +Cc1cc(CN(C)C(=O)c2cnn(-c3ccccc3)c2C)no1 +CCc1ccc2occ(CC(=O)Nc3cccc(C)n3)c2c1 +CCOc1ccc2c(c1OC)C(c1ccccn1)NCC2 +CC(C)C(NC(=O)c1cc2cccn2cn1)C(=O)N1CCCC1 +Cc1ccc2onc(CNC(=O)NCc3ccccc3)c2c1 +Cc1cccnc1NC(=O)Cn1nc(C)c(N)c1C +Cc1cccc(C)c1OCC(=O)Nc1nc(-c2cccn2C)cs1 +O=C(CCC(O)c1ccc(F)cc1)N1CCCc2ccccc21 +CCc1cc(C#N)c(NC(=O)c2cnn(-c3ccncc3)c2C)s1 +Cn1nc(C(C)(C)C)cc1C(=O)Nn1cnc2ccccc2c1=O +CC1CN(Cc2csc(NC(=O)Cn3cnnn3)n2)CC(C)O1 +CN(C(=O)Cc1cccc2ccccc12)C1(C#N)CCC1 +CC(CCc1ccccc1)NC(=O)CCc1ccco1 +c1ccc2c(c1)OCC(c1nc3ccccc3[nH]1)O2 +CCC1CCCC(NC(=O)c2c(C)oc(C)c2C)C1 +Fc1cccc(F)c1NCc1noc(-c2cccs2)n1 +Cc1cc(NCc2nncn2CCc2ccccc2)n2nc(C)cc2n1 +Cc1nc2n(n1)C(CC(=O)Nc1ccc(F)c(Cl)c1)C(=O)N2 +Cc1cnn(CC2CCCN2C(=O)c2cncn2-c2ccccc2)c1 +Cc1ccc(C(C)NC(=O)Cn2cccn2)cc1C +Cc1ccc(C)c2sc(N(C)CC(=O)N3CCOCC3)nc12 +Cc1nc(NC(C)Cc2cccnc2)cc(C(C)C)n1 +COc1cccc(-c2nnn(CC(=O)NC(C)c3ccccc3)n2)c1 +CN(Cc1ccccc1)C(=O)C1CC2CCCC(C1)C2=O +C#CCNC(=O)N1CC(Oc2ccccc2Cl)C1 +CC(=O)NCC(=O)NCC(=O)Nc1cccc(F)c1F +CCC(C)NC(=O)c1ccc(CNC(=O)C(C)C)cc1 +COc1ccc(O)c(C(=O)N(C)Cc2ccc(F)c(F)c2)c1 +COc1cccc(C(=O)N2CCc3c(N)cccc32)c1 +COc1ccc2nc(C(=O)N(C)Cc3cccnc3)ccc2c1 +Cc1ccc(NC(=O)C2(C)CC2(Cl)Cl)cc1F +O=C(NCc1cc[nH]n1)c1ccc(Br)cc1 +O=S(=O)(NCC1COCCO1)c1ccc2c(c1)CCN2 +O=C(CCCn1cccn1)N1CCC(c2nc3ccccc3[nH]2)CC1 +Fc1ccc(Cc2noc(CSc3nnnn3C3CC3)n2)cc1 +CCOc1cc(F)ccc1NC(=O)CCSc1ccccn1 +O=C(COC(=O)c1cccc(F)c1)NCc1ccccc1 +COc1ccc(NC(=O)NCc2cccc(C)n2)c2cccnc12 +COc1cccc(OC)c1C(=O)Nc1cccc(CO)c1 +COC(=O)N(C)CC(=O)NC1CCCCNC1=O +COC(=O)CN(C)C(=O)C12CCC(C)(C(=O)O1)C2(C)C +CC(C)C(NC(=O)c1ccc2nnnn2c1)c1nc2ccccc2[nH]1 +c1ccc(-c2nc(CN3CCOC(C4CCCO4)C3)cs2)nc1 +OC(COc1ccc(-c2nnco2)cc1)Cn1nnc2ccccc21 +COCCCNC(=O)N(C)Cc1ccc2c(c1)OCO2 +CC1CC(C(=O)N2CCC(=O)Nc3ccccc32)C1 +CC(C)NC(=O)N(C)c1ccc(OCC(=O)N(C)C2CC2)cc1 +O=C(Oc1ccccc1Br)c1cnc2ccccn2c1=O +CC(C)NS(=O)(=O)c1ccc(N(C)Cc2ccc(F)cc2)nc1 +Cc1cccc(C(=O)N(Cc2cccnc2)CC2CCCO2)c1O +CCC(C)(C)NC(=O)CSc1nc(C=Cc2cccs2)n[nH]1 +CCn1c(C(N)=O)cc2cc(NC(=O)c3ccccc3F)ccc21 +CC(=O)Nc1cccc(-c2nc(-c3cc4ccccc4o3)no2)c1 +COc1ccccc1-c1noc(COC(=O)c2cc(Cl)c[nH]2)n1 +COCCOc1ccccc1C(=O)Nc1cc(C)nn1C +CC(C)n1ccc(C(=O)Nc2nnc(-c3ccn(C(C)C)n3)o2)n1 +CNS(=O)(=O)CC(=O)NC(C)Cc1ccc(Br)cc1 +O=C(CNC(=O)c1ccccc1)Nc1ccc(F)c(F)c1F +CCc1nnc2n1CCN(C(=O)c1cc(C)nc3[nH]nc(C)c13)C2 +CN(Cc1cccc2ncccc12)C(=O)CCn1nnc2ccccc21 +COc1cc(Cl)c(C)cc1NC(=O)c1cccc(O)c1 +CCc1onc(C)c1NC(=O)COc1ccc(C(C)=O)cc1OC +Cc1cc2c(SCc3nc(N)c4ccccc4n3)ncnc2s1 +O=C(c1ccccc1)N(Cc1ccc(F)cc1)Cc1ccco1 +CC(C(=O)Nc1ccc(S(N)(=O)=O)cc1)N1CCc2ccccc21 +NC(=O)Nc1cnn(Cc2ccc(Cl)cc2)c1 +Cc1cccc(C(=O)Nc2cccc(-c3noc(C)n3)c2)c1 +C=CCNc1nc(C(=O)OCc2ccc(C#N)cc2)cs1 +Cc1cc(C)n2nc(C(=O)N3CCNCC3C(=O)NC3CC3)cc2n1 +COc1ccc(C)cc1NS(=O)(=O)c1cc(C)sc1C +O=C(c1ccoc1)N1CCc2ncnc(-c3ccncc3)c2CC1 +O=C(CS(=O)c1ccccc1)NCCC1CCCCC1 +CC1CC(C)(C)CC(CO)(NC(=O)c2cnn(C)c2)C1 +Cc1cc(C(=O)Nc2nc3c(s2)CN(C)CC3)on1 +CC(=O)NCC1CN(Cc2ccc(F)cc2Br)CCO1 +COc1cc(C)c(NC(=O)C2(C#N)CCCC2)cc1OC +CCC(=O)N1CCCN(C(=O)c2cccc(S(C)(=O)=O)c2)CC1 +O=C(Cn1nc(C(F)(F)F)cc1C1CC1)Nc1ccccc1F +Cc1ccc(N)c(C)c1NS(=O)(=O)c1ccccc1 +CCCCc1nnc(NC(=O)C(C)Sc2ccccn2)s1 +CC(=O)NC(C)C(=O)NC1C2CCOC2C1(C)C +N#Cc1ccccc1Cn1nc(-c2ccc(F)cc2)ccc1=O +CC(C)NC(=O)Cc1ccc(NC(=O)c2cc3cccnn3n2)cc1 +CCCc1c(C)[nH]c2ccc(NC(C)=O)cc2c1=O +O=C(NCCc1cn2ccccc2n1)c1cccnc1 +CN1CCN(C(=O)c2cnc(C(C)(C)C)nc2N)CC1 +O=c1cc(-c2ccccc2)nc(NCCN2CCOCC2)[nH]1 +Cc1ccc(C)c(CC(=O)N(Cc2ccco2)CC2CCCO2)c1 +Cc1nnc(CN(C(=O)c2ccncc2Cl)C(C)(C)C)o1 +COC(=O)c1ccc(OC(=O)c2cn(C)nc2C(F)(F)F)cc1 +CCCC1CN(C(=O)c2n[nH]c3ccccc23)CCO1 +CC(=O)NCCNC(=O)NCC1(c2ccc(F)cc2F)CC1 +COc1cccc(NC(=O)COc2ccccc2C#N)c1 +COc1ccc(Cl)cc1NC(=O)NCc1ccco1 +Cc1cc2c(cc3c(=O)n(CC(=O)NC4CC4)nc(C)n32)s1 +NC(=O)c1csc(CN2CCN(C(=O)CC(F)(F)F)CC2)c1 +CNS(=O)(=O)c1cccc(CNC(=O)c2ccoc2)c1 +CCOC(CC)C(=O)Nc1ccc(N2CCOCC2)cn1 +COC(=O)CC(c1ccncc1)c1c(O)n[nH]c1Cc1ccccc1 +Cc1cc(C)n(C)c(=O)c1C(=O)N(C)CCC(O)c1ccccc1 +COc1ccccc1-c1noc(CN(C)Cc2nccn2C(F)F)n1 +COCc1noc(C(C)Sc2nnc(C3CCC3)n2C)n1 +COCCN(c1ncc(N)cc1C(N)=O)C1CC1 +O=C(Nc1ccc2c(c1)OCO2)c1noc2c1CCc1ccccc1-2 +CSc1ccc(Cl)c(C(=O)OCC(=O)C2=NC=CC2)c1 +Cc1ccc(-n2nnnc2SC(C)C(N)=O)cc1 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1ccc2c(c1)C(=O)NCC2 +Cc1noc(CNC(=O)c2cccc(Oc3cnccn3)c2)n1 +Cc1ccc(C(N)=O)cc1Oc1nc(-c2ccncc2)nc2c1CCC2 +Clc1cc(NCc2cnc[nH]2)c2ncccc2c1 +Cc1ccc(C)c(NC(=O)c2ccc(Cn3cncn3)cc2)c1 +O=C(CCCNC(=O)c1ccco1)OC1CCCCC1 +CCCOc1ncccc1CNC(=O)c1csc(C)n1 +Cn1ccnc(NC(=O)c2ccc(C(=O)NCC(C)(C)C)cc2)c1=O +COC(=O)c1cccc(C(=O)Nc2nnc(C)s2)n1 +CC1c2cccn2CCN1C(=O)Nc1ccc(Cl)cc1 +CNS(=O)(=O)c1ccc(CNC(=O)NC(C)c2cccnc2)cc1 +C=CCn1nnc(NC(=O)C(C)Oc2ccc(Cl)cc2Cl)n1 +Cc1oc(C)c(C(=O)Nc2cccc(C#Cc3ccccn3)c2)c1C +CCC(C)NC(=O)C(C)n1nc(C(F)(F)F)c(Cl)c1C1CC1 +CCN1CC(C(=O)NCc2ccc(Oc3ccccc3)nc2)CC1=O +CC(=O)NC(C)C(=O)NCC(O)c1c(Cl)cccc1Cl +O=C(NCc1nc2ccccc2[nH]1)c1ccc2c(c1)OCCO2 +Cc1cc(CNC(=O)N2CCC(c3cc4ccccc4[nH]3)CC2)no1 +O=c1c(NCc2cccs2)nccn1-c1cccc(Cl)c1 +CCCCC(=O)Nc1sc2c(c1C(=O)NC1CC1)CCC2 +CC(C)(C)OC(=O)Nc1ccc(C(=O)NCCC2CCCO2)cc1 +O=C(CN(Cc1ccccc1)C(=O)c1ccoc1)NCc1ccco1 +CC(NC(=O)CCn1cc(Cl)cn1)c1ccccc1 +CC1CN(CCOCCOc2ccc(C#N)cc2)CC(C)O1 +CC(C)N(C(=O)c1cc(F)c(Cl)cc1Cl)C1CCOCC1 +Cc1cnc(NC(=O)NC2CCC(O)CC2)s1 +O=S(=O)(Nc1cn[nH]c1)c1ccc(F)cc1Cl +Cc1csc2ncc(C(=O)Nc3nc4c(s3)CCC4)c(=O)n12 +CCc1cccc(NC(=O)COc2ncnc3sccc23)c1 +COc1ccccc1C(=O)Cn1cnc2nc(SC)sc2c1=O +CC(C)Cc1noc(C(C)NC(=O)c2cc3sccc3[nH]2)n1 +Brc1cccc2c1C(Cn1cnnn1)NCC2 +Cc1ccc(C(=O)Nc2cccc(Br)c2)o1 +CC(C)c1nc2cc(C(=O)N(C)C3CCOCC3)ccc2o1 +CCOc1cc(C#N)ccc1OC(=O)c1ccccn1 +Cc1nc(C(C)(C)NC(=O)C(C)Oc2cccc(C#N)c2)sc1C +Nc1ccc(Oc2ccc3cn[nH]c3c2)c(Cl)c1 +COc1ccc(-c2oc(C)nc2C#N)cc1C(C)C +CCCNC(=O)c1cnc2c(c1)c(C#N)cn2Cc1ccccc1 +Cc1cccc(C(=O)NCCc2nc(-c3cccs3)no2)c1 +CC(C)c1nnc(-c2sccc2NC(=O)c2ccsc2)o1 +COc1ccc(NC(=O)c2ccc[nH]2)cc1N1CCCC1=O +CCOc1ccc(CCc2nc(C)c(CO)s2)cc1 +N#CCCn1c(C2CC2)nc2cc(Br)cnc21 +Cc1nc(CNC(=O)Nc2ccc(-c3csnn3)cc2)oc1C +COc1ccc(C(=O)c2ccc(OC)c(N)c2)cc1 +COc1ccc(CC(=O)Nc2nc(-c3ccc(N)cc3)cs2)cc1 +N#CCCN(Cc1cccnc1)Cc1cccc(C(F)(F)F)c1 +CCN(C(=O)c1cnccn1)C(Cc1ccc(C)cc1)C1CC1 +COc1ccccc1COC(=O)CCn1c(=O)oc2ccccc21 +Cc1cc(NC(=O)N(C)Cc2nccn2C(F)F)c2ncccc2c1 +CSc1ccc(S(=O)(=O)Nc2ccc(F)cc2)cc1 +CC(=O)NCCNc1ncnc2scc(-c3ccc(C)cc3)c12 +Cc1ccc(C2Oc3c(cc(N)c(C)c3C)N(C)C2=O)cc1 +CN(C)S(=O)(=O)c1csc(C(=O)NCC2CCCO2)c1 +CCC(C)(NC(=O)Nc1ccc(C(=O)NC)cc1)c1nc(C)cs1 +CCc1onc(C)c1NC(=O)CNc1ccc(C#N)cc1 +NC(=O)C1CCCN(C(=O)c2c[nH]nc2-c2ccccc2F)C1 +CNS(=O)(=O)c1cc(C(=O)N2CC(C)CC(C)C2)ccc1OC +COc1ccc(C(O)CNC(=O)C(C)C)cc1C(C)(C)C +CC(O)CCN(C)C(=O)Nc1cnc(C(C)(C)C)nc1 +CN(Cc1ccccc1)C(=O)c1cccc(OCC(F)F)n1 +Cc1cccc(C(C)C)c1NC(=O)NCC(C)(O)c1ccsc1 +Cc1ccccc1CNC(=O)N1CCN(c2ncccc2C#N)CC1 +O=C(Nc1nc2ccccc2[nH]1)c1ccc(N2CCCCC2=O)cc1 +COC(=O)CCC(=O)NCc1cccc2c1OCO2 +CS(=O)(=O)Nc1cccc(C(=O)OCc2ccccc2)c1 +Cc1cc(C)c(NC(=O)CCNC(=O)Cc2ccccc2)c(C)c1 +O=C(C1CC1c1ccccc1)N1CCN(Cc2ccccn2)CC1 +O=C(NCC#Cc1ccccc1Cl)NCc1cccs1 +CN(Cc1ccccc1)C(=O)CNC(=O)C1CCCC1 +COc1ccc(OC)c(NCC(O)c2cc(F)ccc2F)c1 +Cc1ccc(NC(=O)c2sc(C)nc2C)c(OCC2CCCO2)c1 +CC(CNC(=O)Cn1ccccc1=O)N(C)c1ccccc1 +N#Cc1ccccc1OCC(=O)NCC1(c2ccc(F)cc2F)CC1 +CCOC(=O)c1ccc2c(c1)nc(CNc1ccc(C#N)cc1)n2C +O=C(c1ccc2cc[nH]c2c1)N(Cc1ccncc1)Cc1cccnc1 +O=C(NCCc1ccccc1)N1CCCCC1C1OCCO1 +CC(c1ccccc1F)N(C)C(=O)CCC1CCCO1 +O=C(Nc1ncn(CC(=O)N2CCCCCC2)n1)c1ccco1 +CCn1ccnc1N1CCN(C(=O)COc2ccc(C)cc2)CC1 +CC(NC(=O)c1cnc(-c2ccncc2)nc1)c1nc2ccccc2[nH]1 +COc1ccc(C(=O)NC(C)C(=O)N2CCc3ccccc32)nn1 +NC(=O)C1Cc2ccccc2CN1C(=O)Cc1cn2ccsc2n1 +O=C(CCC(=O)n1ncc2ccccc21)NCc1ccccc1Cl +CC(C)NC(=O)CCc1nnc(-c2ccccc2)o1 +COc1cccc2ccc(CN(C)Cc3cccc4ncccc34)nc12 +N#CC(CC(=O)NCc1ccncc1)C1CCCCC1 +CC(NC(=O)Nc1ccccc1)C(=O)NCCc1ccccn1 +N#CCCSc1nccn1-c1ccc2c(c1)OCO2 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)Nc1ccc(Cl)cc1 +COc1cc(O)cc2c1CCNC2c1ccc(F)nc1 +NC(=O)COC(=O)c1ccc(-n2cnc3ccccc32)nc1 +Cc1cccc(O)c1NCc1cnn2ccccc12 +CCCn1cc(NC(=O)COCc2ccccc2Cl)ccc1=O +CC(C)Oc1ccccc1CNC(=O)c1csc(-c2nc[nH]n2)n1 +CCC(=O)c1ccc(OCc2nc(C3CCOC3)no2)cc1 +COCCNc1ncnc(Nc2nc3ccc(C)cc3s2)c1N +COCCNC(=O)c1sc(Nc2ccc(C)cc2C)nc1C +CCOc1ncccc1C(=O)Nc1cc(Cl)ccc1C(N)=O +NC(=O)CN1CCOC(c2cc(F)c(Cl)cc2Cl)C1 +Cc1cc(C)cc(NC(=O)c2nc3ccccc3n(C)c2=O)c1 +Cc1cc(C(=O)Nc2ccc(-c3nc(C)c(C)o3)cc2)[nH]n1 +CC1(C)OCC2(CO1)CN(C(=O)c1cnc3ccccc3n1)C2 +Cc1cc(C)nc(SCC(=O)Nc2ccc3c(c2)CCO3)n1 +N#Cc1ccccc1CNc1cccc2c1OCCO2 +CC(Oc1ccc(C#N)cc1)C(=O)NCC(F)(F)F +CCC(=O)N1CCCN(C(=O)c2cccc3ncccc23)CC1 +COCCN1CCN(C(C)c2nnc(-c3ccc(C)cc3)o2)CC1=O +CN(Cc1cccc(Cl)c1Cl)C(C(N)=O)c1cccc(F)c1 +CCOC(=O)N1CCN(CCC(=O)Nc2ccc(F)cc2)CC1 +O=C(CCNC(=O)c1cc2cccn2cn1)NC1CCCCC1 +Cc1sc2ncnc(NCCOc3ccc4c(c3)OCO4)c2c1C +Cc1cnn(CCC(=O)OCc2cccc(Br)c2C)c1 +COCCC(=O)NC(c1noc(C)n1)c1ccccc1OC +CCCC(C)(NC(=O)c1ccccc1F)C(=O)OC +Cc1cnc2c(c1)N(S(=O)(=O)c1ccc(C#N)c(Cl)c1)CCO2 +Cc1ccccc1C(=O)NCCc1nc2ccccc2s1 +COC(=O)C1Nc2cc(F)ccc2S(=O)(=O)N1 +Cc1ccc(F)c(NC(=O)CCn2c(=O)[nH]c(=O)c3ccccc32)c1 +COC(=O)CN(C)C(=O)COc1ccccc1N +Cc1cnn(CC2CCCCN2C(=O)c2ccc3c(c2)OCCO3)c1 +CN(C(=O)C1CCCN1C(=O)Cc1cn2ccsc2n1)C1CC1 +Cc1noc(C)c1S(=O)(=O)N1CCN(Cc2cccs2)CC1 +CC(Cc1ccccc1)C(=O)Nc1cccc(C#N)c1 +O=C(Nc1cnc(-n2ccnc2)nc1)c1cccc(C(F)(F)F)c1 +CCCNC(=O)CN1C(=O)CCn2nc(-c3cccc(Cl)c3)cc21 +CC(C)S(=O)(=O)c1ccc(Cn2cc(Br)cn2)cc1 +COCCNC(=O)C1(C)CCC(=O)N1Cc1cccc(OC)c1 +Cc1cnc(NC(=O)C2CCCN2C(=O)OC(C)(C)C)s1 +Cc1cc(CNc2nc3nonc3nc2N2CCCCC2)nn1C +CCOc1ccc(-n2ncc(C(=O)NCCC(C)C)c2C)nn1 +O=C(CCc1nc(-c2ccncc2)no1)Nc1ccc(F)cc1Cl +COC(=O)c1cc2c(=O)n(CCc3cccs3)ccc2nc1C +CN(C(=O)Cc1csc(-c2ccoc2)n1)c1ccc(F)cc1 +Cc1cn(C(C)C)c(=O)c(C#N)c1-c1ccncc1 +CS(=O)(=O)NCC1CCCN(C(=O)c2cc(C3CC3)[nH]n2)C1 +Cc1ccc(N2CC(C(=O)NC3CCCCC3)CC2=O)cc1F +O=C(NCCSc1ccc(Cl)cc1)Nc1cn[nH]c1 +CCc1nnc(CN2CCN(CC(C)C)C(=O)C2C)o1 +Cc1nc(C)c(C(=O)NCc2ccc(N3CCCCC3=O)cc2)s1 +COc1ccc(Br)cc1CNC(=O)NC1CC1 +COc1cccc(F)c1C1NCCc2ccccc21 +Cn1cc2c(n1)C(COCC1CC1)CN(Cc1ccco1)C2 +N#Cc1cc(NC(=O)c2cccc(N3CCOC3=O)c2)ccc1F +CC(C)N1CCC(N2CCc3ccc(Cl)cc3C2)C1=O +COC(=O)CCC(=O)Nc1ccc(-c2csnn2)cc1 +Cn1cc(Cl)c(C(=O)n2cnc3ccccc32)n1 +Cc1nc(-c2cc(C)n(CC(=O)NCc3ccco3)c2C)cs1 +CCN1CCc2nc(NC(=O)C(C)c3c(C)nn(C)c3C)sc2C1 +CC(=O)Oc1ccc(C2NCCc3c(F)cccc32)cc1 +N#CCC1(c2ccc(Br)cc2)COC1 +c1ccc(Cn2nnc3c(NCc4ccco4)ncnc32)cc1 +Nn1c(SCCc2ccccn2)nnc1-c1cccs1 +O=c1[nH]cc(C2NCCc3cc4cc[nH]c4cc32)cc1Cl +C#CCN1CCC(C(=O)Nc2cc(C#N)ccc2NCCC)CC1 +CCC(C)C(C)NC(=O)Nc1cccc(NC(=O)OC)c1 +Cc1ccsc1CNC(=O)c1ccc(O)c(Cl)c1 +CN1C(=O)C(C)(C)c2cc(-c3ncc(N)cn3)ccc21 +Cc1ccc2cc(C#N)c(SCC(=O)N3CCCC3)nc2c1 +CC(OCC(F)(F)F)C(=O)N=c1[nH]c2cc(Cl)ccc2n1C +Cc1cc(NC(=O)c2nonc2C)n(-c2ccc(F)cc2)n1 +CCCC(=O)Nc1sc2c(c1C(=O)NC)CCCCC2 +O=S(=O)(NCC#CCN1CCOCC1)c1ccccc1 +Nc1ccc2nc(Oc3ccc(F)cc3)sc2c1 +Cn1ncnc1SCC(=O)NC(C)(C#N)C1CC1 +COc1ccccc1-c1c[nH]cc1C(=O)NCC1Cc2ccccc2O1 +Fc1cc(F)cc(CNc2cnn(CC(F)(F)F)c2)c1 +O=C(NCCc1n[nH]c(=O)[nH]1)c1cc(F)cc2cccnc12 +Cc1ccncc1NC(=O)N1CCN(c2ccccc2O)CC1 +Cc1[nH]c2ccc(OCc3ccccc3)cc2c(=O)c1C#N +CCOC(=O)c1ccc(NC(=O)c2csc(-n3cccc3)n2)cc1 +CCn1c(=O)n(CC)c2cc(C(C)O)c(Cl)cc21 +COc1cccc(NS(=O)(=O)c2ccc(OC)cc2OC)c1 +c1ccc(CCCSc2nnnn2C2CC2)cc1 +Cc1cccc(C(=O)N2CCC3C2CCN3S(C)(=O)=O)n1 +CCOC(=O)CCNC(=O)NC(C)c1cccnc1 +COc1ncccc1CNc1cc(C(N)=O)c2ccccc2n1 +Cc1cc(C)c(C)c(S(=O)(=O)NCC2(O)CCOCC2)c1C +CCOCC(=O)N1CCn2c(nnc2-c2ccccc2)C1 +Cc1nc2ccccc2n(CC(=O)NCc2ccccc2Cl)c1=O +CC(C)CC(=O)Nc1cccc(CNC(=O)NCCO)c1 +CCCCc1nnc(NC(=O)NCc2cnc(C)s2)s1 +c1ccc2c(c1)CCC21CC1CNc1ccc2nnnn2n1 +CCOC(=O)CNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +NC(=O)c1ccccc1OCc1c(F)c(F)c(F)c(F)c1F +CC1CCN(C(=O)COC(=O)c2cccc(O)c2)CC1 +CS(=O)(=O)NCCCNC(=O)c1n[nH]c(=O)c2ccccc12 +CNS(=O)(=O)c1ccc(OCC(C)C)c(N)c1 +Cc1cccc(N)c1C(=O)Nc1ccc2c(c1)OCCO2 +COc1ccc(NC(=O)CCn2ccccc2=O)cc1OC(F)F +COc1ccccc1CC(=O)Nc1cccc(SC)c1 +COCCN1CCN(C(=O)Nc2cc(C(C)(C)C)on2)CC1=O +O=S(=O)(N1CCc2ccccc2C1)N1CCCC1c1cccs1 +CCCC1CCC(NC(=O)NCCc2c(C)nn(C)c2C)CC1 +CCCn1c(=O)n(CC(=O)Nc2nccs2)c2ccccc21 +Cc1ccc(N2CC(C(=O)N3CCOCC3)CC2=O)cc1 +CN1CN(C2CCCCC2)Cc2ccccc2C1=O +Cc1nc(CC(=O)N(C)Cc2cccc3cnccc23)cs1 +O=C1NCC2(CCCN(C(=O)CCNC(=O)c3ccc(F)cc3)C2)O1 +CCC(NC(=O)c1ccc2[nH]cnc2c1)c1ccc(OC)cc1 +CCOc1ccc(NC(=O)CSc2ccncc2)c(C)c1 +COCCn1nc(-c2ccc(C(C)C)cc2)cc(C#N)c1=O +Fc1ccc(C2CN(Cc3ccon3)CCO2)cc1Cl +O=C(NCCNS(=O)(=O)c1cc(Cl)ccc1Cl)C1CC1 +COC(=O)c1nc(C(C)(C)C)ncc1Br +Cc1ccc(NC(=O)N(C)C)c(C(=O)NCCC(C)C)c1 +N#Cc1ccc(CNC(=O)CCC2CCCC2)cc1 +CCn1c(C)cc(C)c(C(=O)N2CCC3(CCCO3)CC2)c1=O +COC1CCN(C(=O)c2ccnnc2)C1Cc1cnn(C)c1 +CCCN(Cc1ccccc1)C(=O)NCCNC(C)=O +CNS(=O)(=O)c1ccc(C(=O)NCCNC(C)=O)o1 +COc1ccccc1OCC(=O)Nc1ccccc1NC(C)=O +COC(=O)c1cnc(SCC(=O)c2ccccc2)n1C +N#CC1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 +Cc1cc(=O)c(O)c(CN2CCN(CCO)CC2)n1C(C)C +CC(C)CNC(=O)c1cn(C2CCC(NC(=O)C(C)C)CC2)nn1 +O=C(Cn1cnc2cc(-c3ccccc3)sc2c1=O)NC1CC1 +CC(NS(=O)(=O)c1cccc(F)c1)c1ccccc1F +Cc1cc(C)n(C2CCN(C(=O)c3ccccc3-n3cncn3)C2)n1 +CC(C)n1nnnc1CN1CCOCC1CC(=O)c1ccccc1 +Cc1cccc(OC(C)C(=O)Nc2ccccc2C(N)=O)c1 +CN(CCC#N)C(=O)c1cc(C#CCO)ccc1F +CCN(C(=O)c1cc(COc2ccccc2F)[nH]n1)C1CCOCC1 +Cc1nc(COc2ccc(F)cc2Cl)nc(C)c1N +COc1ccc(CNC(=O)c2nnc(-c3ccccc3)o2)cc1 +COCC(=O)N1CCN(Cc2nc(C)no2)CC1 +CC1CCCCN1C(=O)c1ccc(-c2cccnc2)nc1N +O=C(NCc1ccc2c(c1)OCCO2)c1ccc(Br)cc1 +C=CCOc1cccc(NC(=O)c2ccc(N(C)C)nc2)c1 +O=C(NCCc1nc(-c2ccccn2)cs1)c1cc2ccccn2c1 +COc1cc(CNC(C)C(=O)Nc2ccccc2)cc(OC)c1 +O=S(=O)(c1cc(Cl)ccc1Cl)N1CCCCC1 +CC(C)C(C)CC(=O)N(CCC(N)=O)c1ccccc1 +Cc1c(C(=O)Nc2cccc(-n3cnnn3)c2)oc2ccccc12 +O=C(Nc1cccc(NC(=O)N2CCCC(CO)C2)c1)C1CC1 +C=CCN(CC=C)S(=O)(=O)c1ccc(F)c(F)c1F +CC(=O)c1sc(-c2cccc3[nH]cnc23)cc1N +O=C(Nc1ccsc1)c1cccc(OCC(F)F)n1 +CC(=O)N1CCCn2nc(C(=O)N(C)CCC3CCCCO3)cc2C1 +O=C(NCc1ccccn1)c1occc1CSc1ccccc1 +O=C(COc1ccccc1F)NCCOc1ccc2c(c1)OCO2 +Cc1ccc(NC(C)C(=O)N2CCCC2)cc1S(=O)(=O)N(C)C +Cc1nc(CCN(C)C(=O)c2cc(-c3ccsc3)n[nH]2)no1 +CC1(C)C(=O)Nc2c(F)cc(C(O)C(C)(C)C)cc21 +Cc1nc2cc(C3CCCN3C(=O)c3cscn3)nn2c(O)c1C +CCc1noc(CC)c1CNC(=O)c1cc(C)n(C2CC2)c1C +Cc1cccc(NC(=O)Cn2c(C)cc(=O)c3cccc(F)c32)c1 +COC(=O)C1CCCN1C(=O)C1CC(=O)N(CCc2ccccc2)C1 +COc1cc(-c2nc(-c3ccc(C#N)cn3)no2)ccc1OC(F)F +CCS(=O)(=O)N1CCOC2(CCCC2COC)C1 +Cc1cc(F)ccc1CCNC(=O)CCc1ccncc1 +COc1ccc(CC(C)(O)CNS(=O)(=O)c2cccs2)cc1 +COc1ccnc(NC(=O)c2cncc(-c3ccc(Cl)cc3)c2)c1 +COc1cc(CCC(=O)Nc2n[nH]c3c2c(C)nn3C)cc(OC)c1 +CCNC(=O)NC1COC2C1OCC2n1cc(-c2ccccn2)nn1 +CCCCn1nccc1NC(=O)COC1CCCC(C)C1 +CCOC(=O)c1ccc(NC(=O)CCn2ccc(C)n2)cc1 +CCOC(=O)c1cc(OC(C)=O)c2cc(OC)cc(OC)c2c1 +O=S(=O)(NCC1Cc2ccccc2O1)c1cccs1 +Cc1ccc(C(=O)N2CCCCC2CNC(N)=O)cc1Cl +CC(OCC1CC1)C(=O)N1CCCN(Cc2nccn2C)CC1 +CCCCc1noc(CN2CCN(C(=O)N(C)C)CC2)n1 +Cn1nc(C2CCN(C(=O)c3cccc(F)c3)CC2)n(C2CC2)c1=O +O=C(c1ccc(Cn2cccc2)cc1)N1CCN(CCO)CC1 +CCn1c(C2CCN(C(=O)c3ccoc3)C2)nc2cccnc21 +CCc1ccc(NC(=O)Cc2cn(C)c3ncccc23)cc1 +Cc1nc(Oc2cccnc2)c2cnn(-c3ccc(F)cc3)c2n1 +O=S(=O)(Nc1ncccn1)c1cc(F)ccc1F +Cc1cccc(C(=O)N2CCCC2c2cccc(F)c2)n1 +Cc1cc(CS(=O)(=O)c2nccn2-c2cccc(C)c2C)on1 +COc1ccc(NC(=O)Cc2csc(C)n2)c(C(=O)NC2CC2)c1 +CCCCCN(C)S(=O)(=O)c1cccc(N)c1 +CN(C)C(=O)c1cc(OC2CC2)ccc1OC(C)(C)C +O=C(NCc1ccc(F)cc1)c1cccc(-n2nnc3cccnc32)c1 +CCNC(=O)C(C)NC(=O)c1oc2cc(OC)ccc2c1C +COc1ccc(CNc2noc(C(C)C)n2)cc1OC +CC(C)(C)NC(=O)N1CCCC1CS(N)(=O)=O +O=C(c1cnn2ccccc12)N1CC2CC(C1)C1CCCC(=O)N1C2 +Nc1nc(=O)n(C2CCC(CO)O2)cc1Br +Cc1cc(C(=O)NC2CCCCC2)ccc1N(C)S(C)(=O)=O +OC(COC1CCCCC1)CN1CCN(c2ccccc2F)CC1 +O=C(NC1CCC(O)CC1)c1cc2c(s1)-c1ccccc1CC2 +COC(=O)C1CC(=O)N(c2ccc(NC(C)=O)cc2)C1 +N#CCc1ccccc1C(=O)Nc1cccc(F)c1 +COc1ccccc1CNCCc1cccc(C(N)=O)c1 +CCc1ccc(S(=O)(=O)N2CCCC2c2ccco2)cc1 +COc1ccc(-c2cnc(NCc3ccccc3OC)n2C)cc1 +COc1cccc(COCCNC(=O)c2cnc3ccc(C)cn23)c1 +NC(=O)c1ccccc1NC(=O)c1cc2c(s1)CCCCC2 +CCn1ccc(NC(=O)CNC(=O)c2ccnn2C)n1 +CCn1cc(C(=O)Nc2cn(C)nc2C(=O)NC)cn1 +CCNC(=O)Cc1csc(NC(=O)c2ccc(Cl)cc2)n1 +CC(=O)c1c(C)[nH]c(-c2csc(NCCc3cccs3)n2)c1C +COc1ccccc1OCCCCN1CCOCC1 +CCOC(=O)CN(C(=O)C(C)NC(N)=O)C(C)C +Cn1cnc2c1c(=O)n(Cc1ccc(Cl)cc1Cl)c(=O)n2C +COCCOc1ccc(CNc2nc(C)cc(C)n2)cn1 +Cc1ncsc1C(=O)NCc1ccnc(OC2CCCC2)c1 +COC1CCN(c2cc(C(C)C)nc3ccnn23)C1 +COc1ccc(C(=O)Nc2nnc(C)s2)c(OC)n1 +CC(C)CCNC(=O)N1CCN(CC(=O)NCc2ccccc2)CC1 +c1ccc(Cn2cc3c(n2)C(CNCc2cccs2)OCC3)nc1 +Cc1ccc(CNC(=O)Nc2ccc(F)cc2F)n1C +CCc1ccc(NC(=O)CCc2c(C)nc3ncnn3c2C)cc1 +CC(=O)Nc1ccc(NS(=O)(=O)c2cn[nH]c2)cc1C +COc1ccc(NC(=O)c2cccc(-n3cnnn3)c2)cc1OC +CS(=O)(=O)c1nccn1CCc1ccc(F)cc1 +CCN(Cc1ccncc1)C(=O)c1ccc(Cn2nc(C)cc2C)cc1 +O=C(NCCn1nnn(-c2cccs2)c1=O)C1CC1 +Cc1ccccc1NC(=O)N1CCN(CC(N)=O)CC1 +COc1ccccc1Nc1nc(N)c2ccccc2n1 +CCOc1ccc(NC(=O)C2CC3CCC2O3)c(C(F)(F)F)c1 +Cc1c(C(=O)N2CCCC2c2ccco2)cnn1-c1ccncc1 +CC(C)OCCSc1nnc(N2CCOCC2)n1C +O=C(CSc1c[nH]c2ccccc12)NCc1ccc2c(c1)OCO2 +COc1cccc(C(=O)OCC(=O)N2CCc3ccccc3C2)c1O +CCN(CCNC(=O)Nc1cccnc1OC)c1cccc(C)c1 +COc1ccc(NC(=O)NCc2ccc(C)cc2)cc1 +O=C(CCCn1cncn1)NC1CCCOc2ccc(F)cc21 +COc1ccccc1CCNC(=O)CCc1ccc2c(c1)OCO2 +COCCOc1ncccc1C(=O)N1CCOc2ccc(F)cc21 +CC(C)c1ccc(C(=O)Nc2cccc(S(C)(=O)=O)c2)cc1 +CCOC(C)C(=O)NC1CC(=O)N(C)C1c1ccc(Cl)cc1 +C1Cc2nc(C3CC3)nc(Sc3nnc(N4CCCC4)s3)c2C1 +CC(=O)c1cccc(OCC(=O)Nc2ccc(F)cc2F)c1 +COC(=O)c1ccccc1OCCN1CCC(C#N)CC1 +CC(C)(C)n1ncc2c1N=C(O)CC2c1cccc(O)c1 +N#CCn1ccn(-c2cccc(Cl)c2)c(=O)c1=O +Cc1[nH]c(-c2ccccc2)nc1C(=O)NCCS(=O)(=O)N(C)C +O=C(Nc1cccnc1)N1CCN(C(=O)C2CCC2)CC1 +CCn1c(=O)n(COC)c(=O)c2c3c(cnc21)C(=O)CC(C)(C)C3 +COc1cccc(CNC(=O)CCOc2ccccc2C)c1 +CCc1nnc(-c2coc(S(=O)(=O)N3CCCC3)c2)o1 +N#CCCN(Cc1ccco1)C(=O)Nc1ccc(Cl)cc1 +N#CCCN(CCC(F)(F)F)CC(=O)N1CCOCC1 +O=C(CCc1ccc2c(c1)OCO2)N1CCCn2ncnc21 +CCCCc1cn(CC2CCCN(C(=O)c3cnc[nH]3)C2)nn1 +CCn1nc(C)c(CCN(C)C(=O)Nc2cccc(C)c2C)c1C +CC1(C)CN(C(=O)c2cc(Br)ccc2F)CCO1 +COc1ccc(CNS(=O)(=O)c2cccc(Cl)c2F)cn1 +CC(C)Cc1nnc(NC(=O)N2CC(C)CCC2C)s1 +O=C(CCC(=O)N1CCOCC1)Nc1ccc(F)cc1 +CCC(C)N(C)C(=O)Nc1ccc(C)cc1OCCOC +O=C(NCCNC(=O)c1ncoc1-c1cccs1)c1cccnc1 +O=C(CCNC(=O)c1csc2c1CCCC2)NC1CCCC1 +Cc1cccc(NC(=O)CCc2nc3ccccc3[nH]c2=O)c1 +CCC1CCCCC1OCC(O)c1cccc(N)c1 +CC(C#N)C(=O)N(C)C(C)c1ccc(Cl)cc1 +COc1cccc(OCC(=O)NCCn2ncccc2=O)c1 +O=C(NCc1nc2ccccc2[nH]1)C1(c2cc(-c3ccco3)on2)CC1 +COc1cccc(C(=O)Nc2cnc3ccccc3c2)c1F +CCOC(=O)c1c(C)cn(Cc2ccccc2)c1C +Cc1cc(C2CCCN2C(=O)c2ccnc(-n3cncn3)c2)no1 +CCn1ncc(-c2ccc(C)c(Cl)c2)c(CO)c1=O +COc1ccnc(NC(=O)Cn2c(=O)[nH]c3ccccc3c2=O)c1 +CN(c1ncnc2c1cnn2C)C1CCCCCC1 +Cc1c2c(nn1C)C(c1ccccc1)=NCC(=O)N2 +Oc1cc(-c2ccco2)nn1-c1nc2ccccc2[nH]1 +Cc1n[nH]cc1NS(=O)(=O)c1cccc(F)c1F +CCCC(C)C(=O)Nc1cccc(C(=O)Nc2nccs2)c1 +C=CCn1nnnc1Sc1ncnc2sc(CC)cc12 +CC(C)NC(=O)CN(C1CCCCC1)S(=O)(=O)c1ccccc1 +CCC(C)(NC(=O)c1ccc2nnc(C)n2c1)C(=O)OC +Cc1ccc(C(=O)Nc2cccc(NC(=O)c3cccnc3)c2)cc1 +Cc1cc(NC(=O)CSc2nnc(C)n2N)no1 +COc1cc(C(=O)Nc2ccc(F)c(Cl)c2)cc(OC)c1OC +CC(C)S(=O)(=O)NCc1ccnc(OCC(F)(F)F)c1 +CNC(=O)NCC(=O)NCc1ccc(-c2cccc(C)c2)cc1 +O=C(Oc1ccccc1)C1COc2ccccc2O1 +COc1cc2c(cc1O)NC(=O)CC2c1ccc(-c2cc[nH]n2)s1 +CCOc1ccc(C(O)CN(C)Cc2ccccc2)cc1 +Cc1nnc(NC(=O)c2ccc(Oc3cccc(F)c3)o2)s1 +CC(=O)Nc1ccc(OC(=O)COc2ccc(Cl)cc2)cc1 +Cc1cc(C)cc(OCc2nnc(SCC(C)(C)O)n2N)c1 +Cc1ccsc1C(=O)N1CCN(c2ccccc2F)CC1 +NC(=O)c1csc(C(=O)N2CCN(Cc3ccccc3)CC2)c1 +Cc1nn(CC(=O)C(C#N)c2nc3ccccc3s2)c(C)c1Cl +CC(C)c1nc(CN(C)C(=O)c2ccc(-c3nc[nH]n3)cc2)no1 +Cc1ccnn1-c1ccc(C(=O)NCCC(=O)Nc2ccccn2)cc1 +COc1ccc2nc(N3CCOCC3)c(C#N)cc2c1 +CN1CCN(c2ccc(-c3nc(Cc4ccccc4)no3)cn2)CC1=O +COc1ccc(CNC(=O)Cn2cccc2-c2nnc(C)o2)cc1 +Cc1cc(OC(C)C(=O)NCCOc2cccnc2)ccc1Cl +COc1ccc(CNc2ccc(O)cc2F)cc1O +COc1ccccc1NC(=O)c1ccc(N)c(C)c1 +CC1CCCCC1N(C)C(=O)CS(=O)(=O)c1ccccc1 +CC(=O)N1CCCN(C(=O)c2cncc(Br)c2)CC1 +Cc1noc(C)c1CNC(=O)C1CCCN1S(N)(=O)=O +Cc1cc(N2CCn3c(nnc3-c3ccccc3)C2)n2ncnc2n1 +COc1ccc(C(C)=O)cc1COc1cccc2c1CCC2=O +O=C(NCCc1n[nH]c(-c2ccc(Cl)cc2)n1)c1cccc(F)c1 +CC(NC(=O)c1ccc(Cl)c(Cl)c1)c1ccc(N)cc1 +CCCOCc1ccccc1CNC(=O)N1CCCC1 +CC(C)Oc1nccnc1NCc1ccc(C(=O)N(C)C)cc1 +Cc1cc(C(=O)N2CCC3(CC2)NC(=O)CC3c2cnn(C)c2)no1 +COCCOc1ccc(Br)cc1C(=O)NC(C)C +Cc1ccccc1C(=O)N(C)Cc1ccccc1F +Cc1nc(CCCC(=O)N2CCc3ccccc3CC2)cs1 +Cc1cc(NC(=O)CCC(C)C)nc2nc(C(F)(F)F)nn12 +N#Cc1cccnc1NCCNC(=O)Nc1ccc(F)c(F)c1F +CC(NC(=O)N1CCCC1)c1cccc(OC(F)F)c1 +CC(C)OCCN1C(=O)C(C)Oc2cc(N)ccc21 +COC(=O)c1cc2cc(F)cc(Br)c2o1 +Cc1ccc(C(=O)OC(C)C(=O)N2CCCC2)c(O)c1 +CC(C)NC(=O)c1ccc2nnc3ncn(C4CCCC4)c3c2c1 +COc1ccc(S(=O)(=O)NC(C#N)C(C)C)cc1C +CCc1nnc2c3cnn(-c4ccc(C)cc4C)c3ncn12 +Cc1cccnc1CN1CCN(C(=O)c2ccn(C(C)(C)C)c2)CC1 +CN(CC(F)(F)F)c1nc2c(s1)C(=O)CC(C)(C)C2 +CCOc1ccc(CN(C)S(=O)(=O)c2cccc(C)c2)cc1OC +O=c1c2nnc3ncnn3c2ccn1C1CCCCC1 +CC(=O)c1cccc(S(=O)(=O)Nc2ccc(OC(C)C)cc2)c1 +CC(C)(C)c1noc(CCCC(=O)N2CCC(C(N)=O)CC2)n1 +CC(=O)N1CCN(S(=O)(=O)c2cc(C)sc2C)CC1 +COc1ccc(NS(=O)(=O)N2CCCCC2)cn1 +CC(C)(O)c1cnc(COc2ccc(Cl)cc2)s1 +NC(=O)C(NC(=O)c1ccc(Cl)cc1)c1ccccc1 +O=C(NCC1CCCO1)Nc1ccc(Oc2ccc(F)cc2)nc1 +N#Cc1ccc(NC(=O)CCN2CCOC2=O)cc1 +COc1ncccc1N(C)C(=O)c1cnc(C2CCCO2)s1 +Cc1nccn1-c1ccc(C(=O)Nc2nc3ccccc3s2)nn1 +CCN(CC)C(=O)Cn1c(-c2ccccc2)nc(C)cc1=O +c1csc(-c2nc(CSc3ncn[nH]3)co2)c1 +COCC(=O)Nc1ccc2oc(-c3ccccc3F)cc(=O)c2c1 +CC1CCCN(C(=O)CNC(=O)c2ccoc2)C1 +COc1ccc2c(ccn2CC(=O)NCCCc2cn[nH]c2C)c1 +CCNC(=O)c1ccc(NC(=O)CCc2cnn(C)c2)c(C)c1 +COCCCNC(=O)c1cc(C2CC2)nc(SC)c1C#N +CNc1snnc1CSc1nnnn1C1CC1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCC1CCCCC1 +CCC(NC(=O)c1ccc(C)[nH]c1=O)c1nc(C(F)(F)F)cs1 +Cc1ccccc1NC(=O)CCCc1nc(C(C)C)no1 +CCCn1c(C)nnc1SCc1nnc(Cc2ccccc2C)o1 +Cn1nc(C(=O)N2CCC(C(O)c3cccs3)CC2)ccc1=O +O=C(NC1(c2ccc(Br)cc2)CC1)c1ccc(=O)[nH]c1 +O=C(NCCc1nccn1Cc1ccccc1)Nc1cccnc1 +CCOC(=O)c1csc(Cc2ccc(-c3csnn3)cc2)n1 +COC(=O)CCCN(C)C(=O)C1COc2ccc(F)cc2C1 +CCn1nc(C)cc1C(=O)NCC(=O)Nc1cccc(COC)c1 +Cc1cccc(NC(=O)c2sc(N(C)C)nc2C)c1 +COc1cc(C(=O)C(C#N)c2nc(C)cs2)cc(OC)c1OC +CC1CCCC(NC(=O)N2CCCC(CO)C2)C1 +O=C(NCc1ccnc(OC2CCC2)c1)C1CC2CCC1C2 +COc1cccc(C(O)c2cc(F)c3c(c2)CC(=O)N3)c1 +Cc1cccc(C)c1NC(=O)Cc1noc2ccc(N)cc12 +Cc1n[nH]c(C2CN(CCS(=O)(=O)c3ccccc3)CCO2)n1 +N#Cc1ccc(CN2CCN(C(=O)c3cc(F)cc(F)c3)CC2)cc1 +COc1ccc(OC)c(C(=O)NCCC(=O)Nc2ccc(C)cn2)c1 +Cc1c(C(=O)NCc2nncn2C2CC2)oc2ccccc12 +CCC(=O)N1CCCN(Cc2ccc(C(=O)OC)c(F)c2)CC1 +O=C(CN1CCCC1=O)N1CCN(Cc2ccc3c(c2)CCO3)CC1 +O=C(NCc1ccccc1)c1cc(-c2cccs2)on1 +CCCCNc1ncnc(Oc2cccc3cccnc23)c1N +COC(=O)c1sc2ccccc2c1CNC(=O)c1cnn(C)c1C +COc1ccc2c(C)c(CC(=O)NCCC(C)C)c(=O)oc2c1OC +COc1cc(OC)c(OC)c2c1CCNC2CC#N +O=C1CC(C(=O)N2CCCC2c2ccccc2)CN1C1CC1 +Cc1ccc(OCC(=O)OCC2CCCO2)cc1C +Cn1ccnc1SCc1ccc(C(=O)NCCO)o1 +N#CCc1ccc(NC(=O)NCc2nnc3ccccn23)cc1 +Cc1ccc(NC(=O)c2ccc(NC(N)=O)cc2)c(C)c1 +CC1c2cccn2CCN1C(=O)c1ccc(Br)c(F)c1 +CC1CCCN(S(=O)(=O)c2ccc3c(c2)CCN3)C1 +Cc1ccccc1CNC(=O)c1ccc(NC(=O)c2ccco2)s1 +CN(C(=O)NCC(C)(C)c1ccncc1)C1CCC1 +CC(C)Oc1ccccc1CNC(=O)NCC(O)C(F)(F)F +CC(CNC(=O)NCC(=O)NC(C)(C)C)Oc1ccccc1 +Nc1ccccc1C(O)CSc1ccc(Br)cc1 +Cc1cn(-c2ccc(C(C)C)cc2)c(=O)c(C#N)c1C +CCCn1nc(CNC(=O)c2n[nH]c3ccccc23)c2ccccc21 +CNC(=O)CSc1nnc(-c2ccc(OC)c(OC)c2)n1C +CCCNC(=O)CNC(=O)Nc1ccc(C)c(Cl)c1 +CCOc1cc(C)c(Cl)c(C)c1C(=O)CN1CCOCC1 +CC(C(=O)N1CCCCC1CCO)n1ccnc1-c1ccccc1 +CCNC(=O)C1CCN(c2nc3ccccc3n3cccc23)CC1 +CCn1nc(C(F)(F)F)cc1C(=O)Nc1ccc2c(c1)OCCO2 +CCC(C)NC(=O)c1ccccc1NC(=O)c1ccc(F)cc1 +Cc1[nH]c2ccccc2c1C(=O)Nc1ccc(NC(=O)C2CC2)nc1 +CSc1ccc(N2CC(C(=O)N3CCCCC3C)CC2=O)cc1 +Cn1nccc1C(=O)Nc1nc2c(Br)cccc2s1 +CN(CCCNc1c(C#N)c(=O)n(C)c(=O)n1C)c1ccccc1 +CCOC(=O)c1cnc(-n2nc(C)cc2C)nc1NCCO +CCC(=O)N1CCN(CCc2nc(-c3ccccc3)no2)CC1 +Cc1cc(=O)c(C(=O)N(CCC(C)C)C2CC2)nn1-c1ccccc1 +COc1ccc(CCn2c(CO)nc3cc(Cl)ccc32)cc1OC +CS(=O)(=O)NC1CCCN(C(=O)CCn2cccn2)C1 +O=C(Nc1ncc(-c2ccccc2)s1)c1csnn1 +Cc1cc(C)cc(NC(=O)Cn2c(C)cc(=O)c3cccc(F)c32)c1 +CC1CCCN(C(=O)NCc2cnn(Cc3ccccc3)c2)C1 +CC(Sc1nnnn1C)C(=O)Nc1ccc(C(C)(C)C)cc1 +COC(=O)c1cccc(C(=O)NCC(C)(C)c2ccncc2)c1 +CCn1cnnc1CNC(=O)N(C)Cc1csc(C)n1 +CC(=O)Nc1ccc(-c2nccn2-c2ccc3cn[nH]c3c2)cc1 +O=C(NCCNc1cn[nH]c(=O)c1Cl)c1cccnc1 +C#CCNC(=O)c1sc(-c2ccc(C)cc2C)nc1C +Cc1ccccc1C(O)CNS(=O)(=O)N1CCCC(C)C1 +CCOc1ccccc1NC(=O)C(C)NC(=O)c1cccs1 +CN1C(=O)C2(CCN(C(=O)c3ccccc3F)C2)c2ccccc21 +COc1ccc(C(C)Nc2ncccc2C#N)cc1F +CC(C)Cn1nc(C(=O)Nc2ccccn2)c2ccccc2c1=O +CCNc1ccc(CCC(=O)CN2Cc3ccc(Cl)cc3C2=O)o1 +Cc1ccc(C)c(S(=O)(=O)N2CCN(C(C)C#N)CC2)c1 +CCOCC1CCCN(C(=O)NC2CCCn3nc(CC)nc32)C1 +O=C(Nc1cccc(C(F)(F)F)c1)c1ccc2[nH]cnc2c1 +COc1cccc(S(=O)(=O)NCC(O)c2sccc2C)c1 +N#CCCN(CCC#N)S(=O)(=O)Cc1cc(Cl)cc(Cl)c1 +Nc1ccc(Cl)c(S(=O)(=O)N2CCCCC2CO)c1 +COCCNC(=O)N1CCC(Cc2ccccc2)C1 +Cc1ccccc1CN(C)C(=O)CSc1nnc(C(C)(C)C)n1N +COc1ccc(C(=O)OCC(=O)Nc2ccc(C(N)=O)cc2)c(F)c1 +CCC(CC)C(=O)Nc1nc(C2CC2)c(C(=O)OC)s1 +COc1ccc(C2C(C(=O)NC3CC3)CCC(=O)N2C)cc1 +Cc1cc(NC(=O)CSc2cc(N3CCCCC3)ncn2)on1 +Cc1cc(NC(=O)c2[nH]nc(C3CC3)c2Cl)ccc1-n1cnnn1 +CC1CN(Cc2ccccc2)CCN1C(=O)c1n[nH]c2ccccc12 +Cc1nc(C(C)(C)NC(=O)c2cccc3ncccc23)sc1C +Cn1cnnc1CCC(=O)N1CCC(CCc2ccccc2)CC1 +CCNC(C)(C#N)CCCOc1cc(F)cc(F)c1 +CCC(C)n1nccc1NC(=O)c1cccc(-c2noc(C)n2)c1 +C#CCN(Cc1ccc(F)cc1)Cc1cccc(O)c1 +Cc1cc(SCC(=O)N2CCOCC2)n2ncnc2n1 +O=S(=O)(Nc1cnc2ccccc2c1)c1ccccc1F +Nc1c(Cl)cc(NC(=O)c2ccccn2)cc1Cl +CC(C)(C)OC(=O)N1CCN(CC(=O)c2cccc(N)c2)CC1 +CCOC(=O)C1(c2cccc(Br)c2)CC1 +Cc1noc(C)c1CC(=O)Nc1ccc(OCC(F)(F)F)cc1 +COc1ccc(CNC(=O)NCC(O)c2ccsc2)cc1 +CCCCNC(=O)c1ccccc1NC(=O)COC +CC(C)n1c(CCNC(=O)c2cccc(F)c2)nc2cccnc21 +Nc1c(Cl)cc(C(=O)NCCCOCC2CCCO2)cc1Cl +Fc1cc(F)c2c(c1)CCNC2Cn1cnnn1 +COCCn1cnc(-c2nc(C(=O)NC3CC3)c3ccccn23)c1 +CNC(=O)c1ccc(Cl)c(NC(=O)C(C)OCC2CCCO2)c1 +CN(C)C(=O)CNC(=O)c1cccc(-n2cccc2)c1 +COC(=O)c1sc2ccccc2c1C(=O)OC +CCc1ccccc1CNC(=O)NCC(O)c1ccccc1F +CN1CCCC2(CCN(C(=O)CCN(C)S(C)(=O)=O)C2)C1=O +COc1ccccc1C1(CNC(=O)NCC(=O)N(C)C)CC1 +Cc1cc(-n2cnnc2)ncc1-c1ccc(N)cc1 +Cc1ccc(NC(=O)C2CCN(C(=O)Cc3ccc[nH]3)CC2)nc1 +Cc1oc(=O)oc1CSc1ncnc2ccccc12 +Cc1cc(C(=O)N2CCC3OC(COCC4CC4)CCC32)no1 +Cc1nn(-c2ccccc2)c(-n2cccc2)c1C(=O)N1CCOCC1 +CSc1ccccc1N(C)C(=O)c1cn(C)nc1-c1cccs1 +CC(C)C(NC(=O)c1cc(COc2ccccc2)[nH]n1)C(N)=O +O=C(CCc1cc2ccccc2[nH]c1=O)NCc1cnccn1 +CCOCCC(=O)N(C)c1cccc(SC)c1 +COc1ccccc1S(=O)(=O)NCC#Cc1ccc(N(C)C)cc1 +O=C(NC1CC1)c1cc(-c2cccs2)nn1Cc1ccc(F)cc1 +Cc1ccc(NC(=O)NCc2ncn(C)n2)c(Cl)c1 +Cc1cc(C)n(-c2ccc(-c3nc(-c4ccc(C#N)cn4)no3)cn2)n1 +Cc1cc(C)cc(C2(C(=O)NCC3CCOC3)CC2)c1 +Cc1c(C(=O)OCC(=O)NC(C)C(C)C)cnn1C +CCC(C)Sc1nnc(Cc2csc(C)n2)o1 +O=C(Cn1cncn1)N1CCC(c2nc3cc(Cl)ccc3o2)CC1 +CCN(CC)C(=O)C(c1ccccc1)N1CCC(C(=O)OC)CC1 +O=C(CCC(=O)c1ccc(F)c(F)c1)Nc1ccccn1 +COc1ccc(CNc2ccc(S(=O)(=O)N3CCCC3)cn2)cc1 +CCc1ccc(C(=O)CCC(=O)N2CCN(CCO)CC2)cc1 +CC(C)(C)c1cc(NC(=O)Cc2ccsc2)[nH]n1 +CC(C)c1ccc(CN(C(=O)c2cc(C(N)=O)cn2C)C2CC2)cc1 +C#Cc1cc(F)c(NC(=O)COc2ccc(OCC)cc2)c(F)c1 +Clc1ccc2[nH]c(-c3nc(-c4cccnc4)no3)cc2c1 +O=S(=O)(Cc1ccc(Br)cc1)Nc1cccnc1 +Cc1nc(C#N)c(Cc2cccc(F)c2)c(C(F)(F)F)n1 +CC1CN(Cc2ccc(CNC(=O)Cc3ccc[nH]3)cc2)CC(C)O1 +Cc1cccc(CN2CCC3(CCCN(C(=O)N(C)C)C3)C2=O)n1 +CC(C#N)CN1CCN(C(=O)c2ccccc2F)CC1 +CCOc1ncccc1C(=O)OCC(=O)Nc1cccc(C)c1 +Cc1cc(NCC(=O)N(C2CCCC2)C2CC2)ccc1C(N)=O +COc1ccc2oc(C(=O)OCC3CCCO3)c(C)c2c1 +N#CCCN(Cc1cccnc1)Cc1ccc(Cl)c(Cl)c1 +N#CC(C(=O)c1ccc(-n2cncn2)cc1)c1ccccn1 +Cc1ccoc1C(=O)OCc1nc(N)c2ccccc2n1 +CC1CCC(NC(=O)Nn2cnc3ccccc32)CC1 +CN(CCC#N)S(=O)(=O)N1CCN(c2ccc(Cl)cn2)CC1 +Cc1ccc(F)c(NC(=O)c2n[nH]c3c2CCC3)c1 +c1cnc(OCC2CCC3C2OCCN3c2cnccn2)nc1 +CN(CC1CC1)C(=O)c1c[nH]nc1-c1ccc2c(c1)OCCO2 +C#CCOc1ccccc1CN1CCCC(c2nnc3ccccn23)C1 +CC(Cn1cccn1)NC(=O)c1ccc2c(c1)CCCO2 +Cc1ccc(C(C)C)cc1OC(C)C(=O)NCC(C)O +CC(C)Oc1nnc(SCC(=O)N(C2CCCC2)C2CC2)s1 +Cn1cc(C(=O)CSc2ccccc2Br)cn1 +O=S(=O)(N1CCOCC1)N1CCOCC1C1CC1 +CN(C)C(=O)N1CCn2nc(CNC(=O)c3cccs3)cc2C1 +CCc1ccc(CN2CCN(Cc3cnn(CC)c3)CC2)s1 +O=C(NCC1CCC1)N1CCN(Cc2cccs2)CC1 +Cc1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c2ccc(F)cc2n1 +CCOC(=O)c1cccnc1NC1CCC(O)CC1 +CS(=O)(=O)NC1CCCN(C(=O)NCCCN2CCCC2=O)C1 +CCC(C)NC(=O)NCc1c(C)nn(CCOC)c1C +CC1(C)CCCN1C(=O)c1scnc1C1CC1 +CN(C(=O)COC(=O)COc1ccccc1)c1ccccc1 +CC(C)OCC(=O)Nc1ccc(C(F)(F)F)cc1N +Clc1cc(Cl)c2c(c1)CCNC2c1ccncc1 +Cc1c(NC(=O)CC(C)c2ccccc2)c(=O)n(-c2ccccc2)n1C +CCc1c(C)nc2ncnn2c1NCc1ccc(C)cc1 +CC(=O)N1CCN(C(=O)Cn2nc(C)c(C)c(C#N)c2=O)CC1 +CC(C)(C)C(=O)N1CCC(C(=O)OC2CCCC2)CC1 +O=C(Cc1noc(-c2ccncc2)n1)Nc1ccccc1Cl +Cc1cnc2c(c1)nc(-c1ccc(F)c(F)c1)n2CCO +COc1cc(F)c(NC(=O)c2ccnc(OC3CCC3)c2)cc1OC +C=CCNC(=O)c1cccc(S(=O)(=O)Nc2ccc(OC)cc2)c1 +CCNc1ncc(C(=O)N2CCC(O)(c3ccc(C)cn3)CC2)cn1 +COc1ccccc1C(=O)c1cc(-c2cccnc2)oc1N +Cc1cc(C)n(CCC(=O)Nc2ccccc2-n2cncn2)n1 +CCC(=O)c1ccc(OCC(=O)Nc2ccccn2)cc1 +CCOc1cccc(NC(=O)NC2c3ccccc3CC2O)c1 +Cc1ccc(-c2n[nH]c(NC(=O)c3n[nH]c4ccccc34)n2)cc1 +O=C(CCN1CCOC(C2CCCO2)C1)N1CCc2ccccc21 +COc1cccc(NS(=O)(=O)c2cnc(NC(C)=O)s2)c1 +CCC1CCCC(NC(=O)NCc2ccc(OC)c(O)c2)C1 +CSc1ccc(C(C)NS(=O)(=O)c2cccnc2)cc1 +CC(C)n1cnc2cc(CNC(=O)c3ccnn3C)ccc21 +CN(C(=O)CSc1cc(C#N)ccn1)C1CCCCC1 +CC(C)CNC(=O)c1ccc(NC(=O)c2ccccn2)cc1 +Cc1nc(NCCC(C)C)c2nnn(Cc3ccccc3)c2n1 +CC(C#N)Sc1nnc(NCc2ccccc2)s1 +Cc1ccccc1C(=O)NCC(=O)Nc1ccnn1C1CCCCC1 +Cc1ccc(NC(=O)c2ccncc2)cc1N1CCCC1=O +Cc1csc(NC(=O)Cc2cccc3ccccc23)n1 +NC(=O)C1CCN(C(=O)NCCc2cccc3cccnc23)C1 +O=C(CSc1nccn1-c1cccc(F)c1)NCc1cccnc1 +CCCOc1nc(N(CC)C(C)CC)ccc1N +Nc1ncnc2c1N=CC2C1OC(CO)C(O)C1O +CCCN(CCC)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +COc1ccc(CNC(=O)Cc2c(C)nc(C)[nH]c2=O)c(OC)c1 +Cc1nc(NCc2cccnc2)c2ccccc2c1Br +Cc1nc(N2CCOCC2)c2ccccc2c1Br +O=C(NCCc1ccncc1)c1cc(C2CC2)on1 +Cc1cc(C(=O)NCc2nnc3ccccn23)c(C)s1 +O=C(Nc1ccc(F)c(Cl)c1)c1cccnc1 +Cc1csc(C(=O)N2CCC(c3nnc(-c4ccco4)o3)CC2)c1 +COc1cccc(CN(C)C(=O)COc2cccc(CO)c2)c1 +COc1cccc(NC(=O)COc2cc(F)ccc2N)c1 +O=C(NC1CCc2ccccc21)c1c[nH]nc1-c1ccc(F)cc1 +COC(=O)c1ccccc1NS(=O)(=O)c1ccc(OC)cc1 +CC(=O)N1CCN(c2ccccc2NC(=O)C(C)C)CC1 +CC(Oc1ccc(Cl)cc1Cl)C(=O)N1CCC(O)C1 +COc1cc(CNCCc2ccc(F)cc2)cc2c1OCO2 +COc1ccccc1OCC(=O)N(C)C(C#N)c1ccccn1 +c1csc(CSc2nnc(SCc3nccs3)s2)n1 +COc1ccccc1CNCC(C)(C)N1CCOCC1 +CC(NCC(O)c1cccc(F)c1)c1ccccc1 +CC1CC(C)CN(C(=O)CSc2ccncc2)C1 +CCN(CC1CC1)C(=O)Nc1ccc(CCC(=O)N2CCCC2)cc1 +COc1ccccc1C(NC(=O)c1ccn(C)c(=O)c1)C(C)(C)C +Cn1cnc(CNC(=O)N2CCOC3(CCCCCC3)C2)n1 +CSc1ccccc1NC(=O)Cn1nnn(-c2ccccc2)c1=O +CC1CCC(NC(=O)c2c(Br)cnn2C)CC1 +O=C(NCc1nnc2n1CCCCC2)NCc1nnc2n1CCC2 +CCNc1nc(-c2ccc3c(c2)CCC(=O)N3)cs1 +Nc1ccc(-c2n[nH]c(Cc3ccncc3)n2)cc1 +CCOc1ccc(C(=O)NCc2cn(C)nc2C)cc1OCC +CC(=O)Nc1cc(NC(=O)C(C)Oc2ccccc2C)ccc1C +C#CCN1CCN(C(=O)c2cc(Cl)ccc2O)CC1 +CCOC(=O)CCCNC(=O)Nc1ccc(F)c(Cl)c1 +CCc1n[nH]c(C2CN(C(=O)Cc3csc(C(C)C)n3)CCO2)n1 +O=C(NCC1OCCc2cn(CC3CCOCC3)nc21)c1ccoc1 +COCCOCC1NCCc2ccc(Cl)cc21 +CC1CC(C)CN(S(=O)(=O)c2cn(C)nc2N)C1 +CC(NC(=O)NCCCO)c1ccccc1C(F)(F)F +CC(=O)N1CCCC1CCc1ccc(-c2ccccc2C)nn1 +O=C(Cc1cccc(F)c1)NC1CC(=O)N(Cc2ccc(F)cc2)C1 +CCNc1ccc(C(O)(C(=O)OC)C(F)(F)F)cc1 +Cc1ccc(-c2nnc(CN3CCOCC3)o2)cc1 +CNC(=O)c1cccc(CCNCc2csc(C(C)(C)C)n2)c1 +Brc1cccc2c(NCC3CCOC3)ncnc12 +Cc1cccc(Cn2cnc3c(sc4ncccc43)c2=O)c1 +CCCn1nc(C(=O)NCC2CCN(c3ccccc3)C2)ccc1=O +O=c1sccn1Cc1cccc(C(F)(F)F)c1 +CCN1C(=O)C(c2ccccc2)CC12CCN(c1ncccn1)CC2 +O=C(CSc1ccc(Cl)cc1)Nc1c[nH]c(=O)[nH]c1=O +COCCCn1cnnc1S(=O)(=O)C(C)c1ccccc1 +CCCC(=O)Nc1sc(CC)cc1C(=O)OC +CCN(Cc1ccccc1Cl)C(=O)Nc1cccc(NC(C)=O)c1 +Cc1nn(C)c(C)c1CCC(=O)N1CCC(NS(C)(=O)=O)CC1 +COC(=O)NC(Cc1ccccc1)NC(=O)OC(C)(C)C +COc1ccccc1NC(=O)c1cnn(-c2ccncc2)c1C +CN(Cc1cnn(C)c1)C(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)C(C)C +CCc1ccc(NC(=O)c2ccc(NS(C)(=O)=O)cc2)cc1 +COc1cccc(C(=O)N2CCOC(c3ccccc3C)C2)c1F +O=S(=O)(N1CCCCC1)N1CCN(c2ccc(F)cc2)CC1 +CCCNc1nc(-c2cc(C)n(-c3ncn[nH]3)c2C)cs1 +COCCNC(=O)CN1CCN(C(=O)c2ccc(C)nc2)CC1 +Cc1nc2nc3ccn(CCO)c(=O)c3c(-c3ccc(F)cc3)n2n1 +COC(=O)CCNC(=O)Cc1ccc2c(c1)OCCCO2 +CC(C)(C#N)NC(=O)CCCc1ccc(F)c(F)c1 +COc1cccc(-c2nnc(-c3ccccc3O)o2)c1 +O=C(OCc1ccc(Cl)c(Cl)c1)c1cnccn1 +Cc1ccc(-c2nnc3sc(NC(=O)c4ccco4)nn23)cc1 +Cc1c(NC(=O)c2ccccc2O)c(=O)n(-c2ccccc2)n1C +CCOC(=O)COC(=O)c1cc(Cl)ccc1OC +COC(=O)C1=C(CN2CCCCC2)NC(=O)NC1c1ccc(C)cc1 +Cc1ccc(OCC(=O)NCc2ccnc(OC3CCC3)c2)cc1 +Cn1ccc2c3c(c(Br)cc21)OCC3 +O=C(CCC1CCCN(C(=O)CCN2CCCCC2=O)C1)NC1CC1 +Clc1ccc2[nH]c3c(N4CCCC4)ncnc3c2c1 +Cc1cc(C(=O)Nc2cc(-c3cccnc3)no2)nn1C +C=CCNC(=O)CCC(=O)c1ccc(Br)cc1 +CCNC(=O)C(C)NC(=O)CCc1ccc(F)c(F)c1 +NC(=O)c1cc(NCc2ccc(F)c(Br)c2)ccc1F +Cc1nc(C)c(C(=O)NCCNC(=O)OC(C)(C)C)s1 +COc1ccc(C(=O)CCNc2ccccc2)c(OC)c1 +CCN(C)S(=O)(=O)c1ccc(C)cc1Br +COc1ccc(C)cc1NC(=O)NC(C)c1cccnc1 +Cn1cc(NC(=O)c2c[nH]nc2-c2cccc(OC(F)F)c2)cn1 +CC(=O)N(C)Cc1cccc(NC(=O)c2c[nH]c(C)n2)c1 +CCc1ncc(C(=O)NCCSc2ccccn2)cn1 +CC(=O)c1ccc(NC(=O)C2CSc3nccc(=O)n3C2)cc1 +COc1ccc(C2CCCN2S(=O)(=O)N(C)CC(C)C)cc1 +COc1ccc2[nH]c(C(=O)NCc3ccco3)cc2c1 +O=S(=O)(Nc1cccc(-c2ncon2)c1)c1ccc(F)cc1F +CCC(CO)NC(=O)Nc1ccccc1N1CCCCC1 +Cc1cc(NCc2ccc(C#N)cc2)c2ncccc2c1 +CCN(CC)C(=O)CN1CCOc2ccc(F)cc21 +O=C(NCc1noc(-c2ccco2)n1)c1cccc(Cl)c1 +CC(C)(C(=O)N1CCCC(n2cccn2)C1)n1cc(Cl)cn1 +NC(=O)c1cccc(CNC(=O)c2cc3c([nH]c2=O)CCCC3)c1 +COc1ccc(CCNC(=O)CN2CCc3cc(F)ccc3C2)cc1 +CCC1CCC(NC(=O)Cn2cc(N)cn2)CC1 +CC(=O)c1cccc(NC(=O)Nc2cc(C)cc(C)n2)c1 +Cc1cccc(NC(=O)CSc2ccccc2N)c1 +COCc1nc(CN2CC(Cc3ccccc3)CC2=O)no1 +COCc1ccccc1CNC(=O)c1c(C)c(C)nn(C)c1=O +CCC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(C(N)=O)C1 +COc1cc(F)c2c(c1)C(c1cncs1)NCC2 +CSc1nc(C)cc(C(=O)Nc2cccc(Cn3cccn3)c2)n1 +Cn1ncnc1CCNS(=O)(=O)c1ccc(C(F)(F)F)nc1 +O=C1CN(C(=O)Nc2ccccc2OCC(F)(F)F)CCN1 +COc1ccc(OCCC(=O)N=c2[nH]nc3ccccn23)cc1 +Cc1c(N)c(-c2ccc3c(c2)nc(C(C)C)n3C)nn1C +CCc1ccc(CN(C(=O)c2ccc[nH]c2=O)C2CC2)cc1 +Cc1ccc2c(c1)S(=O)(=O)N=C(NCc1ccccn1)N2 +CC1CCc2onc(-c3nnc(-c4ccccc4)o3)c2C1 +Cc1ccc2c(c1)N(CC(=O)N1CCCC(C)C1)C(=O)CO2 +CCC(NC(=O)c1sccc1C)c1cccc(S(N)(=O)=O)c1 +CCOCC(=O)Nc1ccccc1S(=O)(=O)NC(C)(C)C +CC(C)C(=O)c1cn(CC(=O)NC(C)(C)C)c2ccccc12 +CC(c1cc2ccccc2o1)N(C)S(C)(=O)=O +COc1ccccc1NC(=O)C(C)N1CC(C)c2ccccc21 +COCc1cn(CC2CCN(C3N=CN=C4N=CN=C43)CC2)nn1 +O=C(CCn1c(=O)oc2ccccc21)Nc1ccc(F)cc1Cl +NC(=O)c1cccc(NC(=O)Nc2cccc(Cl)c2)c1 +CC(=O)NC(CC(=O)N(C)CC(N)=O)c1cccs1 +CCCOc1cccc(CNc2ccc3[nH]nc(C(N)=O)c3c2)c1 +CC(CN1CCOCC1)OC(=O)c1csc(-c2cccs2)n1 +CCOC(=O)c1sc(CC(=O)Nc2cccc(C)c2)nc1C +CCc1ccc(S(=O)(=O)Nc2cc(OC)c(OC)cc2F)cc1 +CNc1snc(C)c1C(=O)NC(C)Cc1ccco1 +CCOC(=O)c1cc2cc(C(F)(F)F)ccc2[nH]1 +CC(C)N1CCCC(N2CCN(C(=O)c3ccoc3)CC2)C1=O +COc1cc(O)c2c(c1)C(c1cccs1)NCC2 +O=C(NCc1ccc(C(F)(F)F)cc1)c1cn2c(n1)COCC2 +CC(=O)NC1CCN(c2ccccc2C(=O)N2CCCCC2C)CC1 +CCNC(=O)c1nn(CC2CC2)c2c1CN(Cc1ccccn1)CC2 +Cc1nc(N2CCCCC2)ncc1C(=O)NC1CCC2CCCC21 +CNS(=O)(=O)c1ccccc1N1CCN(C(C)C(=O)OC)CC1 +COCCN1C(=O)CC2C1CCN2C(=O)c1nc[nH]n1 +CCCN1C(=O)C(O)(CC(=O)c2ccncc2)c2cc(Cl)ccc21 +Cc1cc(C(=O)N(CC2CCCO2)c2ccncc2)ccc1F +CCCN(CCC)C(=O)c1nnn(-c2cccc3cnccc23)c1C +CC(NS(=O)(=O)Cc1ccc(C#N)cc1)C(N)=O +Cc1sc2nc(CCC(=O)N(C)CC(F)(F)F)[nH]c(=O)c2c1C +O=C(CSc1ccncc1)NCc1ccccc1-n1ccnc1 +CN(C)c1nc2cc(NC(=O)Cc3noc4ccccc34)ccc2o1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)Nc2ccccc2)c1 +CC(OC(=O)c1cc2sc(Nc3ccccc3)nc2s1)C(N)=O +Cc1cc(C(=O)NC(C)c2ccc(Cl)c(Cl)c2)no1 +COC(=O)C(C)(C)NS(=O)(=O)c1ccc(C)s1 +CCc1cc(=O)n(CC(=O)NCC2CCCO2)c(N)n1 +Nc1ccc(S(=O)(=O)Nc2nccnn2)cc1 +COc1ccc(NC(=O)Nc2ccc(Cl)cn2)cc1 +N#CCC(=O)NCc1ccccc1OCCc1ccccc1 +Cc1nn2c(N)c(C#N)cnc2c1-c1cccs1 +Cc1cc2[nH]c(=O)[nH]c2cc1S(=O)(=O)NCCC1=CCCCC1 +COc1cccc(OC)c1C(=O)N(CC(C)O)CC(C)O +CC1CC(C)CN(C(=O)c2csc(-c3cnn(C)c3)n2)C1 +c1cncc(CN(Cc2cnc(C3CCC3)s2)CC2CCCO2)c1 +CCOc1cc(CNc2cccc(N(C)C)c2)ccc1O +COc1ccc(NC(=O)c2cnc3[nH]ccc3c2)cn1 +Cc1ccnc(Nc2nc(CC(=O)Nc3nc(C)cs3)cs2)c1 +Cc1cc(Br)cc(C)c1NC(=O)NC(C)(C)C +C=CCN(Cc1cccs1)C(=O)Nc1ccncc1 +CCOC(=O)C(CC)N1CCN(c2nccs2)CC1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)N(C)CCC(F)(F)F +Cc1ccccc1NC(=O)N1CCC2CNS(=O)(=O)C2CC1 +Cc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2N)cc1 +O=C(NCc1csc(=O)[nH]1)c1c[nH]nc1-c1ccccc1F +CN(Cc1cccc(F)c1)C(=O)CNC(=O)CC(C)(C)C +COCCc1nccc(-c2nnc3nc(-c4cccnc4)nn3c2C)n1 +CCC(C)NC(=O)N(C)CC1COc2ccccc2O1 +CCc1nc(CN2CCN(Cc3cc(C#N)cs3)CC2)no1 +CN(Cc1ccc(-n2cccn2)cc1)C(=O)c1ccn(C(F)F)n1 +CC(=O)N1CCc2cc(C(=O)NCc3ccc(C)c(F)c3)ccc21 +CC1CN(CCC(O)c2cccs2)CC(C)O1 +COC(=O)c1ccc(CNC2(c3nccs3)CCCC2)o1 +Cc1cccc(NC(=O)C2CC(=O)N(c3ccccc3Cl)C2)n1 +CC(C)(CNC(=O)c1n[nH]c2ccccc12)c1ccncc1 +O=C(c1cccc2c1OCO2)N1CCC(Oc2ccccc2)CC1 +C=CCNC(=O)Nc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1 +COC(=O)c1ccnc(NC(=O)c2ccc(F)cc2)c1 +Cc1ccccc1-c1nnc(S(=O)(=O)CC2CCCO2)n1C +CCC(C)CS(=O)(=O)N1CCCC1C(=O)N1CCN(C)CC1 +CC(C#N)(NC(=O)CSc1ccc(Cl)cc1)C1CC1 +N#Cc1ccc(OCCN2CCOC(Cn3cccn3)C2)cc1 +COc1ccc(CC(C)CNC(=O)c2nc(C)ncc2Cl)cc1 +CCc1ccc(C(C)NC(=O)NCc2cn(-c3ccccc3)nn2)cc1 +O=S(=O)(Cc1cccc(F)c1)N(CC(F)F)C1CC1 +Cc1cc(SCC(=O)Nc2cccc(F)c2)n2ncnc2n1 +CCc1nnc(NC(=O)CCc2ccc(F)cc2)s1 +CC(C)CNC(=O)C1CC2CN(Cc3ccncc3)CC1O2 +CC1CCCC(C)N1C(=O)CN1CCOC(CNc2cccnn2)C1 +Cn1c(N)nnc1SCc1ccc(Cl)cc1Cl +CCCn1c(SC(C)CC)nc2cc(S(N)(=O)=O)ccc21 +Cc1ncnc(C)c1C1NCCc2cc(F)c(F)cc21 +CCN(CC)C(=O)C(C#N)Cc1cc(OC)ccc1OC +COC(OC)(OC)C(C)(C)c1ccc2c(c1)CCC2 +CCCNC(=O)CNC(=O)Nc1ccc(F)cc1F +CCN(CC)C(=O)COc1cccc(NC(=O)c2ccc(C)cc2)c1 +CCCCc1nnc(NC(=O)N(C)C(CC)CC)s1 +O=C(CNc1ccccc1C(=O)Nc1ccc(Cl)cc1)NC1CC1 +Cc1cccc(CN(C(=O)NCCNC(=O)C2CC2)C2CC2)c1 +CC(=O)NCC1CCN(C(=O)c2snnc2C)CC1 +NC(=O)c1ccc(COC(=O)CCc2cccc(F)c2)cc1 +CC(C)OCc1cccc(CNc2c(C#N)c(=O)n(C)c(=O)n2C)c1 +Cc1cccc(C2CC2C(C)NC(=O)c2ccc(C(N)=O)cc2)c1 +NC(=O)C1CCN(C(=O)C2CCCOC2)c2ccccc21 +CCn1nnc2c(C(=O)N(C)Cc3ccccc3)c(C)sc2c1=O +CCOC(=O)CCN1C(=O)C(CC)(CC)Oc2cc(N)ccc21 +Cc1nc2sccn2c(=O)c1S(=O)(=O)NCCC(C)C +CCOC(=O)N1CCC(OC(=O)C2CC2c2ccccc2)CC1 +CC1CCCCC1Nc1nnc(S(=O)(=O)CCCO)s1 +CC(C)c1csc2nc(CC(=O)c3ccco3)[nH]c(=O)c12 +Nn1c(SCc2noc(-c3ccoc3)n2)nnc1-c1cccs1 +CC1CCCC(CC2Cc3cc(O)cc(O)c3C(=O)O2)O1 +Cc1c(C(=O)N(C)C2CCCCC2)sc2nc3ccc(N)cc3n12 +CCNC(=O)CNC(=O)c1cc(N)ccc1Cl +C=CCC(C)CC(=O)N1C2CC3CCC2(CS1(=O)=O)C3(C)C +CSc1ccc(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)o1 +O=C(NCC#Cc1ccccc1Cl)c1cnn(-c2ccccc2)n1 +O=C(NCCc1cccc(F)c1)c1cc2c([nH]c1=O)CCC2 +Cc1cc(C(=O)NCc2ccccc2C(F)(F)F)nn1C +Cc1noc(C)c1CN(C)C(C)c1nnnn1-c1ccccc1 +CC(NC(=O)c1cc(N)c(F)cc1Br)C(N)=O +c1cnc(-c2noc(C3CN(Cc4ccoc4)C3)n2)nc1 +CC(C)N(C)C(=O)c1ccc(N2CCNC2=O)cc1 +Cc1cccc(C(=O)Nc2cc(C(N)=O)ccc2N2CCCCC2)n1 +Cc1noc(C(C)C)c1C(=O)NCCc1ccn(-c2ccccc2)n1 +CC(C)(C)C(NC(=O)Nc1nncs1)c1cccs1 +CC(=O)N(Cc1csc(COc2ccc(Cl)cc2)n1)C(C)C +CCc1ccccc1NC(=O)c1cnc2n(c1=O)CCS2 +N#CC(C(=O)CCCNC(=O)c1cccs1)c1ccccn1 +COC(=O)CCCCNC(=O)Nc1cc(C)cc(C)c1 +CC(C)(C)c1ncn2c1C(C)(C)Nc1ncccc1-2 +CCSc1ncc(CN2CCC(O)CC2C(=O)OC)cn1 +CNC(=O)c1cccc(OC(=O)CCNC(=O)C(C)(C)C)c1 +Cc1nnc(COC(=O)C2(c3ccc(F)cc3F)CCCC2)n1C +CC(C)CC(C#N)N(C)S(=O)(=O)CCc1ccccc1 +Cc1ncsc1C(=O)NCCC(=O)N1CCOCC1 +COCCNC(=O)CN(C)c1nc2c(F)cccc2s1 +Cc1ccc(N2CCCN(C(=O)COc3cccnc3)CC2)nn1 +Cc1nnc2c(=O)n(CC(=O)NC3CCCCC3)c3ccccc3n12 +CCS(=O)(=O)c1ccccc1NC(C)C(N)=O +CCCCC1C(=O)N(C)CCN1C(=O)c1cccc(N(C)C)c1 +CC(NC(=O)Cn1nnc(-c2cccs2)n1)C(=O)N(C)C +COCC(C)NC(=O)c1cc(-c2ccc3c(c2)OCO3)on1 +Cn1c(C(=O)NCc2ccccc2)cc2c(=O)n3ccccc3nc21 +Cc1ccc(-c2cc(C(=O)NCc3cscn3)[nH]n2)cc1 +Cc1sc(=O)n(CC(=O)Oc2ccc3c(c2)CCC(=O)N3)c1C +CC(C)NC(=O)NCc1ccnc(-n2ccnc2)c1 +CCCCN(CCO)S(=O)(=O)c1ccc(C)cc1C +N#Cc1csc(CN2CCOC(c3cccc(O)c3)C2)c1 +Cc1cnc(NC(=O)c2ccc(-n3nc(C)c(Cl)c3C)cc2)s1 +CC(C)NC(=O)Nc1cccc(C(=O)NC2CC(=O)N(C)C2)c1 +COc1ccc(S(=O)(=O)Nc2ccc(-n3cnnn3)cc2)cc1 +COc1ccc2[nH]cc(CCNC(=O)CC#N)c2c1 +COc1cccc(CC(=O)NC2CCC(C)CC2)c1 +Cc1cc(NC(=O)Cc2ccc(Cl)cc2)nn1C +CC(CNC(=O)N(C)CC(O)C1CC1)c1nc(-c2ccccc2)no1 +O=C(NCCc1cccnc1)c1ccc(Cn2cccn2)cc1 +CCc1onc(C)c1NC(=O)c1cc2c(s1)CCC2 +CC(C)(C)NC(=O)c1onc(-c2cccnc2)c1N +CS(=O)(=O)N1CCC(C(=O)c2ccc(F)c(F)c2)CC1 +COc1cccc(-c2nc(COc3ccccc3N)n[nH]2)c1 +COc1ccc(N)cc1NC(=O)c1cccc(C)c1O +CCN(CC)S(=O)(=O)c1ccccc1OC(C)=O +COC(C)c1nc(Cn2c(C)nc(C#N)c2C#N)cs1 +COc1ccccc1CCNC(=O)c1ccc2cn[nH]c2c1 +COC(=O)CSc1nc2ccccc2c(=O)n1C(C)C +Cc1cccc(C(=O)NCC(O)Cc2ccccc2)n1 +Nc1cc(Cl)ccc1NC(=O)CC1CC2CCC1C2 +N#CCOc1ccc(NC(=O)CCc2ccsc2)cc1 +CNC(=O)C1CCC(NC(=O)CCc2ccco2)CC1 +CCC(C(=O)N1CCC(C(N)=O)CC1)c1ccccc1 +COc1ccc(NC(=O)COc2cc(C)ccc2N)cc1 +Cc1nnc(NC(=O)CCc2ccc(=O)n(C)n2)s1 +COc1cccc(CN(C)C(=O)c2cc3cc(F)ccc3[nH]2)c1 +Cc1occc1CN(C)C(=O)Cn1c(C)csc1=O +O=S(=O)(c1c[nH]c2ncccc12)N1CCN(CCCO)CC1 +Cc1ccc(CNC(=O)c2cc(C#N)cn2C)c(OCC2CC2)c1 +COc1cccc(OC)c1C(=O)Nc1nnc(-c2ccncc2)s1 +Cc1cc(OCCc2nc(CN)cc(=O)[nH]2)ccc1Cl +N#Cc1cnc(NC(=O)Nc2ccc(Cl)cc2)s1 +CCOc1cc(C(=O)NC(C)c2ccccc2)ccc1OC +N#CCc1sc(COc2ccccc2F)nc1C1CC1 +CSc1nc2ccccc2c(=O)n1-c1ccccc1 +CCN(C(=O)c1[nH]nc(C)c1Br)c1ccccc1 +CC(C)Cc1nc(NC(=O)c2cc(-c3ccccc3)[nH]n2)n[nH]1 +Cc1cccc(OCC(C)NS(=O)(=O)c2ccccc2)c1 +CC(C)(C)CNC(=O)c1cccc(-n2cccn2)c1F +CSc1nc(C)cc(C(=O)N2CCc3ccccc3C2)n1 +O=C(NCc1csc(C2CC2)n1)c1cc(-c2ccc(F)cc2)on1 +COc1ccc(S(=O)(=O)Nc2cccc(NC(C)=O)c2)cc1C +CCn1ccnc1S(=O)(=O)Cc1ccccc1Cl +COC(=O)c1cccn2cc(CN(C)Cc3ccc(C#N)cc3)nc12 +COc1cccc(C(=O)Nc2c(C)nc3sccn3c2=O)c1OC +COC(=O)c1ccc(CCC(=O)NC(C)c2nc(C)cs2)cc1 +COCCCNC(=O)c1ccc2nc3ccccc3c(=O)n2c1 +CCc1noc(CNc2cc(Br)ccc2OC)n1 +CCCOc1ccc(CNC(=O)c2cc3ccccn3n2)cc1 +Cc1occc1-c1nnc(SCC(=O)NC2CCCCC2)n1C +N#Cc1nnn(CC(O)CO)c1-c1ccc(C(F)(F)F)cc1 +Cc1ccc2c(C(=O)N(C)C)cc(-c3cnc(C4CC4)nc3)nc2c1C +O=C(COC(=O)Cc1ccsc1)Nc1ncc(Cl)cc1Cl +NC(=O)CCN(c1ccccc1)S(=O)(=O)c1ccccc1F +Cc1cnn(-c2cc(N3CCC(C4=NC=NC(=O)C4)CC3)ncn2)c1 +CC(OCC(F)(F)F)C(=O)Nc1ccc(-n2cncn2)nc1 +CCOC(=O)CNC(=O)CSc1nc2c(c(=O)n1C)SCC2 +CCC(C(=O)OC)N1CC(C(C)C)Oc2cccc(N)c21 +O=C(CCc1cscn1)OCc1ccc2c(c1)OCO2 +CC(=O)c1ccc(NC(=O)N(Cc2ccncc2)C2CC2)cc1C +Cc1ccc(S(=O)(=O)N(C)Cc2cccc(F)c2F)cc1 +CC1(C)CC(O)(O)CC(O)(O)C1c1ccccc1 +COc1ccc(NS(=O)(=O)c2cc(-c3ccno3)oc2C)cc1 +Cc1nc(CCNC(=O)C(C(C)C)N2CC(C)OC(C)C2)cs1 +O=C(c1cc2ccccc2c(=O)[nH]1)N1CCc2cc(F)ccc2C1 +Cc1nccn1-c1ncc(NC(=O)C(C)Oc2ccccc2)cn1 +CS(=O)(=O)N1CCCC1C(=O)Nc1cnn(CC(F)(F)F)c1 +COc1cc(C#N)ccc1OC(C)C(=O)N1CCCc2ccccc21 +CC(=O)c1cc2c(Br)ccc(N)c2s1 +O=C(NCC(=O)N1CCc2ccccc21)OCC(F)(F)F +CNC(=O)c1cnc(C=Cc2cc(Br)cs2)s1 +CC(C)Oc1cccc(C2=NC(C3CC(=O)N(C4CC4)C3)N=C2)c1 +CCCc1nnc(NC(=O)NC2CCN(c3ccccc3)CC2)s1 +COC(=O)C(C)(C)NC(=O)c1sc(C)cc1OC(F)F +Cc1ccc(C(=O)OC(C)C(=O)Nc2ccccc2C#N)cc1N +CC1CC1c1ccc(CN(C(=O)Cc2c[nH]c3ncccc23)C2CC2)o1 +CCCOc1cc2c(cc1O)C(=O)CC(C)(C)O2 +Cc1ccccc1C1CC1C(=O)NCCNC(=O)OC(C)(C)C +CC(=O)Nc1ccc(C)c(S(=O)(=O)N(C)Cc2ccccc2C)c1 +CCCCNC(=O)Nc1cc(C(=O)OC)ccc1N1CCCC1 +N#Cc1cccc(C(=O)c2ccc(C3OCCO3)cc2)c1 +Cc1[nH]c2c(c1C(=O)N1CCCC1)CN(C(=O)c1ccccn1)CC2 +O=C(Nc1cn[nH]c1)C1CCCN(C(=O)c2cccs2)C1 +Cc1ccc(Cl)cc1-n1nnc(C#N)c1C1CCCO1 +O=C(Nc1ccc(-n2cnnn2)cc1)c1ccsc1 +Cc1cccc(C(=O)Nc2ccccc2C(=O)OCC(=O)N(C)C)c1 +CC(=O)c1c[nH]c(C(=O)N(Cc2ccccc2F)C2CC2)c1 +O=C1Cc2cc(NC(=O)Nc3cccc4c3CCCC4)ccc2N1 +O=C(COc1ccccc1F)NCCc1csc(-n2cccn2)n1 +Cc1cccc(CNC(=O)Cc2c(C)nc3nc(N)nn3c2C)c1 +Cc1ccc(C2CCCN2S(=O)(=O)N2CCC(C(N)=O)CC2)o1 +CC1(C)CN(C(=O)Cc2ccc[nH]2)CCN1Cc1ccccc1 +CCNC(=O)c1c2c(nc3ccc(F)cc13)CCC2 +Cc1cc(F)ccc1S(=O)(=O)NCC(O)C1CC1 +CC(C)(C)CC(=O)NCC(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +CC(C)CCN(C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +Cc1ccccc1N1CC(C(=O)N(CC(C)C)CC(C)C)CC1=O +COc1ccccc1C(=O)Nc1cc(C(N)=O)ccc1Cl +CC(O)CN(Cc1nnnn1-c1ccccc1)c1ccccc1 +Nc1nccnc1C(=O)OCC(=O)Nc1ccon1 +Cc1ccccc1C(=O)Nc1ccc(CC(=O)N(C)C)cc1 +COc1ccc(C(C)NCCc2ccccn2)cc1F +Cn1nc(CNC(=O)c2ccc(=O)[nH]c2)c2ccccc2c1=O +COc1ccc(CCC(=O)Nc2ccc(N)nc2)cc1OC +N#Cc1ccc(OCCCN2CCN(S(N)(=O)=O)CC2)cc1 +Cc1cc(NC(=O)CNC(=O)c2ccccc2)sn1 +COCc1c(CO)nnn1Cc1ccc(C(C)C)cc1 +c1cnc2ncc(CN3CCOC4(CCCC4)C3)n2c1 +CC(NC(=O)Cn1c(=O)n(C)c2ccccc21)c1ccncc1 +CCOC1CCCN(C(=O)c2ccc(-c3nc(C)cs3)cc2)C1 +COc1ccccc1CNC(=O)NC1CCCCC1C +CCc1ccc(CNC(=O)NCCCC(N)=O)s1 +O=C(Nc1cc(F)ccc1O)c1cnc(C2CCCO2)s1 +Cn1ccc2ccc(C(=O)NCCn3ccc4ccccc43)cc21 +Cc1cc(C)nc(NC(=O)c2cccc(CO)c2)c1 +CCCc1c(C(=O)OCC)cnn1-c1ccccn1 +Cc1ccn2c(=NC(=O)c3cn(C)nc3-c3cccs3)[nH]nc2c1 +COCCNC(=O)C1CC2(CO1)CN(C(C)=O)c1ccccc12 +CCOc1ccc(F)c(C(=O)NCCC(=O)N(C)C)c1F +Cc1ccc(C)c(C(=O)N2CCN(c3cc(C#N)ccn3)CC2)c1 +c1cnc2c(c1)nc(-c1ccncc1)n2-c1ccncc1 +CCOc1ccc(NC(=O)COc2ncnc3ccccc23)cc1 +Cc1cc(N2CCN(Cc3nnc(C4CC4)o3)CC2)nc(C(C)C)n1 +COc1ccc(C(C)N(C)C(=O)c2ccn(C)c(=O)c2)cc1 +CC(C)S(=O)(=O)NCC(=O)Nc1ccc(F)c(F)c1F +Cc1ccc(OC2CCN(C(=O)c3ccc(N(C)C)cc3)CC2)cn1 +COc1ccc(NC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1 +CCCS(=O)(=O)NC(C)c1cccc(NC(C)=O)c1 +COC(=O)CC1CCCCN1S(=O)(=O)N1CCCCC1 +COC(=O)c1ccc(NC(=O)C2CCN(C(=O)C3CC3)CC2)cc1 +CCC(CC)C(=O)N1CCC(NC(=O)CCn2ccccc2=O)CC1 +CC(O)CC(C)CNC(=O)Nc1cccc(N2CCCC2=O)c1 +O=C(Nc1ccc(F)cc1)C1CC(=O)N(C2CC2)C1 +CCOc1cc(C)c(-c2cc(CO)nn2C)cc1C +CCCNC(=O)c1c(C)oc2ccn(Cc3ccc(F)cc3)c(=O)c12 +c1ccc(-c2nnn(-c3nc4ccccc4o3)n2)cc1 +CSc1nnc(CNC(=O)Cc2c(F)cccc2Cl)n1C +CCc1n[nH]c(C2CN(C(=O)Cn3cncn3)CCO2)n1 +O=C(Nc1ccc(Cn2cncn2)cc1)C1CC1c1ccc(F)cc1 +Cc1cccc(OCCCNS(=O)(=O)c2c(C)noc2C)c1 +CC1=NCCN1C(=O)c1cccc(Br)c1 +O=C(NCCCc1ccccc1)c1ccc2[nH]cnc2c1 +Cc1noc(-c2ccc(SCC(=O)NC3CCCC3)nc2)n1 +COc1ccc(C(=O)Nc2nc(-c3ccccc3)ns2)cc1OC +COC(=O)C(C)NC(=O)c1cccc(OCC(F)F)n1 +COC(=O)C(C)n1cnc2c(cnn2-c2ccc(Cl)cc2)c1=O +CN(CC(=O)NC1CC1)C(=O)COc1cccc(Cl)c1Cl +CCC(C)NC(=O)c1ccc(CNC(=O)c2cccnc2)cc1 +CC(Oc1ccccc1Cl)C(=O)NCc1ccoc1 +C#CCN(Cc1ccc(F)cc1)C(=O)CCS(=O)(=O)N(C)C +CC(=O)N1CCN(CC(=O)Nc2c(C)nn(C)c2C)CC1 +COc1ccc(NC(=O)c2cccc(C)c2C)cn1 +CC(=O)N1CCN(c2ccc(Br)cn2)CC1 +CCS(=O)(=O)N1CCN(c2cc(Nc3ccccn3)ncn2)CC1 +COCCOc1ccc(NC(=O)C2CC3CCC2O3)cc1Cl +CC(=O)N1CCC(C(=O)NCCc2cccs2)CC1 +Cn1ccnc1SCC(=O)Nc1ccc(F)c(F)c1F +O=C(Cn1nc2c(cc1=O)CCCCC2)NCc1ccc(Cl)cc1 +CCN(Cc1cccs1)C(=O)c1ccc(F)cc1Cl +CCC(C)C(=O)N1CCC(N(C)c2ccccc2)CC1 +COc1ccc(C(=O)n2ncc(Cl)c(Cl)c2=O)cc1 +COc1ccc(CNc2ccccc2SC)cc1OC +COc1cc(OC)c2c(c1OC)C(=O)NCC21CCCC1 +N#CCC(=O)Nc1ccc(C(=O)Nc2cccc(C#N)c2)cc1 +CCC(C(=O)N(C)c1ccccn1)c1ccccc1 +CC(=O)Oc1ccc(OC(C)=O)c2c1COS(=O)C2 +COC(=O)Cn1ccn(-c2ccc(Cl)cc2)c(=O)c1=O +NC(=O)c1cc(Cl)ccc1NC(=O)CCc1ccc(F)cc1 +Cc1nc(CN(C)C(=O)Nc2ccc(F)cc2F)cs1 +CCC(=O)Nc1cccc(C(=O)Nc2cc(C#N)ccc2SC)c1 +O=C(c1cccc(-c2ncc[nH]2)c1)N(CCO)Cc1nccs1 +Cc1cc(CC(=O)N2CC(C)(C)C(C)(O)C2)on1 +CCC(=O)N1CCCC(C(=O)Nc2c(C(N)=O)oc3ccccc23)C1 +Fc1cccc(CCNCc2cnn3ccccc23)c1 +CCOc1ccc(C)cc1S(=O)(=O)N1CCN(C)CC1 +Cc1cc(CN(C)C(=O)c2ccnc3ccccc23)no1 +CC(C)c1ccc(CC(=O)Nc2nccs2)cc1 +Cc1cc(C)c(NC(=O)c2onc(C#N)c2N)c(Cl)c1 +COc1ccc(C(=O)NC(C)c2ccc(-n3ccnc3)cc2)cc1 +Cn1cc(C2CCCN2C(=O)C2CCCN(c3cnccn3)C2)cn1 +Cc1cc(C(=O)N2CC3COCC3(COc3ccccn3)C2)c(C)o1 +CCN1CCC2(CN(C(=O)C3CCCO3)CC2c2ccccc2)C1=O +CC(c1cc(F)ccc1F)N(C)C(=O)CCc1cnn(C)c1 +CNS(=O)(=O)c1ccc(F)c(C(=O)NCC2CC2C)c1 +CCCn1c(SCC(=O)N2c3ccccc3CC2C)n[nH]c1=O +CCOc1cccc(NC(=O)CCc2cnn(C)c2)n1 +Cc1cc(C)n(C(C)C(=O)Nc2ccc(N)cc2C)n1 +O=C(NCCCn1ccnc1)c1cn(Cc2ccccc2F)nn1 +COc1cccc(NS(=O)(=O)c2ccc(C#N)cc2)c1 +O=C(OCc1cc(-c2ccccc2F)on1)c1ccccn1 +O=C(Nc1cccnc1-n1cccn1)c1cnn(-c2ccc(F)cc2)n1 +CC(c1ccccn1)N(C)C(=O)Nc1ccc(Oc2cccnc2)nc1 +O=C(Nc1cc(-c2ccccc2F)no1)c1ccoc1 +CCn1cc(CN(C)C(=O)c2ccnn2CC)c(C)n1 +O=S(=O)(NCCc1ccc(F)cc1)c1ccc(O)cc1 +Cc1ccc(CNC(=O)c2cc(C)nc3c2c(=O)[nH]n3C)cc1 +CCc1nn(C)c(OC)c1CNc1nnc(C(C)(C)C)o1 +CCc1cc(NS(=O)(=O)c2ccccc2Cn2cncn2)n(C)n1 +Cc1ccc(Br)cc1NCc1cccc(C(N)=O)c1 +Cc1cccc(CNc2cccc(C)c2C(N)=O)c1 +Cc1c(C)c2c(ccc3c(C)cc(=O)oc32)oc1=O +Fc1cccc(C2(c3nnc(C4CCCO4)o3)CCOCC2)c1 +CCOc1ccccc1C(=O)NCc1csc(C2CC2)n1 +COc1ccc(CNCC(=O)NCc2ccco2)cc1 +Cc1cc(F)ccc1CCNC(=O)NCc1cnn(C)c1 +O=C(NCCNC(=O)N(Cc1ccc(F)cc1)C1CC1)C1CC1 +CCN(Cc1ccccc1)C(=O)Cn1cnc(C)cc1=O +O=C(c1cccnn1)N1CCC(C(O)CCc2ccccc2)CC1 +O=C(NCC1CC1)c1cncc(-c2cc(F)ccc2F)c1 +Cn1cc(CCC(=O)Nc2ccccc2C(N)=O)cn1 +Cc1noc(C)c1CCC(=O)NC1CCCCC1 +CNc1nc2nonc2nc1Nc1ccc(C)c(C)c1 +CCC(NC(=O)CN(C)C(=O)OC)c1ccc(Br)cc1 +CC(=O)NC(C(=O)N1CCC(c2ccc(O)cc2)CC1)C1CCCC1 +O=C(Oc1cccc(N2CCCC2=O)c1)C1CC2CCC1O2 +C=CCNC(=O)NCCC(O)c1cccc2ccccc12 +COc1ccc(N2CCn3c(SCC(=O)NC(C)C)nnc32)cc1 +Cc1nc2ccccc2n1CCNC(=O)c1ccsc1 +CC(C)NC(=O)CN(C)C(=O)C1CC1c1ccco1 +CC(NC(C)c1ccccc1Cl)C(=O)N(C)CCC#N +CCc1nnc(NC(=O)CNC(=O)COc2ccccc2)s1 +COCCOc1ccc(NC(=O)C2CC3CCC2O3)cc1F +COC(=O)C(C)CN(C)S(=O)(=O)c1cccc(C(F)(F)F)c1 +Cn1cc(C(=O)NCCOc2ccccc2N)cn1 +Cc1cc(NC(=O)CCc2nc(-c3ccc(F)c(C)c3)no2)no1 +COC(=O)C(C)CN(C)C(=O)c1c[nH]c2cccc(F)c12 +CCc1nc(C2CCCN(C(=O)Nc3cccc(OC)c3)C2)no1 +O=C1CCCc2c1cnc1c(-c3ccccc3)cnn21 +Cc1cc(=O)n2nc(N3CCCC3C(=O)NC3CC3)sc2n1 +COc1cccc(-c2nnn(CC(=O)N3CCc4ccccc43)n2)c1 +COc1cc(OC)cc(C(=O)Nc2ccc(CO)cn2)c1 +COc1ccc(C(=O)N2CC3CCC2CN(C(=O)C2CCC2)C3)o1 +CCn1nc(C(=O)NCCc2ccco2)c(=O)c2cc(Cl)ccc21 +Nc1cc(C2CCN(C(=O)Nc3cccc(Cl)c3)CC2)no1 +c1ncn(Cc2ccc(NCc3ccc4[nH]ccc4c3)cc2)n1 +CN(C)C(=O)c1ccccc1OCc1ccccc1 +CSc1nsc(SCC(=O)c2ccc(F)cc2)n1 +Cc1ccccc1C(C)NC(=O)c1ccc(=O)n(C)c1 +Cc1cccc(C(=O)N2CCCC(C(=O)Nc3cccc(F)c3)C2)c1 +CCC(C)Nc1nnc(-c2c(COC)oc3c2CCC3)s1 +Cc1c(NCc2cscn2)cccc1C(=O)N1CCOCC1 +CC(C)(C)NC(=O)c1cccc(NC(=O)Cn2cnnn2)c1 +Cn1nc(-c2cccc(F)c2)n(-c2ccncc2)c1=O +COc1ccccc1C(=O)CCCC(=O)NC(C)C +Cc1nc(-c2cc(NC(=O)c3ccc(C#N)cc3)c(C)s2)no1 +COc1cccc(C(=O)OC(C)C(=O)NC2CCCC2)c1 +O=C(CNC(=O)c1cccc(Cl)c1)NCc1cn2ccccc2n1 +CCN(CC)C(=O)Cn1cc(CO)c2cccc(C)c21 +CCOc1ccc(C(=O)NCC(=O)Nc2cc(C)ccc2F)cc1 +CC(C)(C)OC(=O)N1CCC(S(=O)c2ccncc2)C1 +Cc1ccc(NC(=O)CN(C)S(=O)(=O)N2CCCC(C)C2)nc1 +CC(Sc1nnnn1C)C(=O)Nc1ncc(Cl)cc1Cl +Cc1cc(C(=O)Nc2ccccc2C(=O)N(C)C)c(C)n1C1CC1 +Fc1cccc(OCC2CCCN(c3cnccn3)C2)c1 +COc1ccc(-n2ccnc2C(C)c2ccccc2)cn1 +Cc1n[nH]c(SCC(=O)N2CCC(Oc3ncccn3)CC2)n1 +CCCNC1C(=O)Nc2ccc(Br)cc21 +COc1ccccc1N1CCN(C(=O)Nc2cccc(F)c2)CC1 +CCCC1CN(C(=O)c2ccccc2NC(=O)OC)CCO1 +Cc1ncc(CNC(=O)N2CCNC(=O)C2)s1 +CCNC(=O)N1CCN(c2nc(-c3ccncc3)nc(C)c2C)CC1 +CCC1(O)CCN(C(=O)c2cnn3c2CCCC3)CC1O +Cc1cc(NC(=O)c2cccc3[nH]ncc23)n(C)n1 +Cc1nn(C)cc1-c1c(C)c(-c2ccc(O)cc2)nc(N)c1C#N +Cc1noc(-c2csc(C(=O)NC3CC3)n2)n1 +Cc1nscc1C(=O)N1CCC(C(N)=O)CC1 +COc1c(C)cnc(CNC(=O)Nc2ccccc2)c1C +Fc1ccc(CN2CCCC3(C2)OCCO3)cc1Cl +Cn1cnnc1C1CCN(c2cnc3ccccc3n2)CC1 +O=C(NCCCOCC1CCCO1)N1CCc2cc(F)ccc2C1 +O=C(NCC(=O)N1CCCC1)c1cccnc1Oc1ccccc1 +O=C(Nc1cccc(CNC(=O)N2CCCC(O)C2)c1)C1CCCC1 +O=C(OCc1ccc(Cl)cc1)c1cnn2cccnc12 +O=S(=O)(NCc1ccccc1F)c1c[nH]c2ncccc12 +COC(C)(C)c1noc(-c2cc(C(C)C)n(C)n2)n1 +CCOC(C)C(=O)N(CC)CC1COc2ccccc2O1 +CC(c1ccc(-n2cnc3ccccc32)cc1)N(C)C(=O)c1cc[nH]n1 +O=C(Nc1cnc(C2CC2)nc1)c1cccc(-n2cccn2)n1 +Cc1ccc(NC(=O)N(C)C(C)CC#N)cc1S(N)(=O)=O +O=C(Nc1ccc2c(c1)COC2)N1CCN(C(=O)c2ccco2)CC1 +O=S(=O)(CCn1cnc2ccccc21)NCC1CCCC1 +CN(Cc1ccccc1F)C(=O)CNc1ccccc1F +CCOC(=O)CN(C(C)C)S(=O)(=O)c1cc(C)ccc1F +O=C(NCC1CN2CCCC2CO1)c1ccccc1 +CCC(CC)C(C(=O)Nc1ncc(C)s1)N1CCOCC1 +Cc1sc2ncnc(Sc3nnc(C(F)(F)F)n3C)c2c1C +CCc1cccc(C)c1NC(=O)COC(=O)Cc1cccc(F)c1 +COc1cc(CNc2cccnc2OC)ccc1F +FC(F)(F)Cn1nc(C2CC2)nc1-c1cccn1C1CC1 +Cc1cccc(Cn2nccc2NC(=O)c2cnc(C)cn2)c1 +CCc1noc(CC)c1CC(=O)NCCc1cc(F)cc(F)c1 +CC(C)n1cnc(S(=O)(=O)Nc2cn[nH]c2)c1 +COc1ccc(OC)c(CN2CCN(C(=O)c3ccoc3C)CC2)c1 +CS(=O)(=O)N1CC2COCC2(CNC(=O)c2ccsc2)C1 +Cc1ccnc(NC(=O)C(C)NC(=O)c2cccs2)c1 +O=C(CC1CCCC1)Nc1cccc(C(=O)N2CCOCC2)c1 +CCCCNc1nc(-c2ccc(CNC(C)=O)o2)cs1 +Cc1ccc(C(=O)N(C)C(C#N)c2ccccc2F)cc1 +COc1cccc(-c2cc(NCc3ccccn3)nc3[nH]ccc23)n1 +CCOc1ccccc1CCC(=O)Nc1cccc(-n2cnnc2)c1 +O=C(OCCC1OCCO1)c1ccc(-c2cnco2)cc1 +OC(Cn1cncn1)(Cn1cncn1)c1ccccc1 +OCc1nnn(-c2ccc(Cc3ccncc3)cc2)c1C1CC1 +Cn1c2ccccc2c2cnn(CC(=O)NCc3ccccn3)c(=O)c21 +Cc1cc(CN2CCN(C(=O)C(C)Sc3ccccc3)CC2)no1 +O=C(Nc1cnc(C2CC2)nc1)c1cccnc1OCC(F)F +C=CCn1c(=O)c2c(nc(-n3nc(C)cc3C)n2C)n(C)c1=O +CC(=O)c1cccc(S(=O)(=O)Nc2ccc(C)c(F)c2)c1 +CCC(CC)C(O)CNC(=O)c1cc(F)ccc1N1CCOCC1 +Cc1cc(C)n(-c2nc(CCNC(=O)C(C)(C)C)cs2)n1 +CS(=O)(=O)NCC(=O)N1CCCN(CC(F)(F)F)CC1 +OCCn1ncc2c(N3CCN(c4ccc(F)cc4)CC3)ncnc21 +CC(=O)c1sc(NC(=O)c2ccccc2C)c(C(N)=O)c1C +CC(C)(C)OC(=O)N1CCNCC1c1ccc(F)c(F)c1 +Nc1c(C(=O)N2CCCc3ccccc32)sc2ncccc12 +Cc1ccc2[nH]cc(C(=O)NCc3cccs3)c(=O)c2c1 +CCN(Cc1ccccc1NC(=O)c1cc(CC(C)C)n[nH]1)C(C)=O +Nn1c(SCCC(=O)NCc2ccco2)nnc1-c1ccncc1 +CC(C)C(=O)Nc1ccc(OCC(F)(F)F)c(C#N)c1 +CCOC(=O)c1sc2nc(C)nc(Nc3cnn(CC)c3)c2c1C +CC1CN(C(=O)CCOCC2CCCO2)CC(C)O1 +CN(CC1CCOC1)C(=O)C1(c2ccc(F)cc2F)CCOCC1 +COC(=O)NCC(=O)N(Cc1cccnc1)C1CC1 +CCNC(=O)CN(CC)C(=O)CCc1c(C)noc1C +COCc1cn(CC2CCN(C(=O)C3CC=CCC3)CC2)nn1 +Cc1ccsc1CNC(=O)c1ccn(C)c(=O)c1 +Cc1c(C(=O)N2CCCN(C)c3ccc(Cl)cc32)cnn1C +Cc1ccn(-c2ccnc(N3CCN(Cc4ccccc4)CC3)n2)n1 +c1ccc(CN2CCOC3CN(CCn4cncn4)CC32)cc1 +CNC(=O)C(C)NC(=O)Cc1ccc(F)cc1F +CN1CCC(Sc2nnc(-c3ccccc3F)n2C)C1=O +O=C1CCc2cc(C(O)c3ccco3)cc(Cl)c2N1 +CCCc1nnsc1C(=O)N1CCOCC1CO +COc1ncccc1CNC(=O)N1CCc2ccc(Cl)cc2C1 +CCc1ccc(C(NC(=O)NCc2ncn(C)n2)C(C)C)cc1 +O=C(c1ccc[nH]1)N1CC2OCCN(CC3CCCO3)C2C1 +Cc1ccc(-c2noc(-c3c(C)cc(C)[nH]c3=O)n2)cc1 +CC(C)C(=O)Nc1ccc(NC(=O)CCC(=O)c2ccccc2)cc1 +COCCOc1ccc(NS(=O)(=O)c2ccc3c(c2)CCC3)cc1 +Fc1cc2c(cc1Cl)C(c1ccc[nH]1)NCC2 +COc1ccc(CCCNC(=O)N2CCCC(NC(C)=O)C2)cc1 +CCCc1nc(N2CCOC(c3ccc(F)cc3)C2)no1 +CCn1nnc2cc(C(=O)NCCCOc3cccc(C)c3)ccc21 +CC(NC(=O)C1COc2ccc(F)cc2C1)C(=O)NCc1ccco1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NC1CCCCCC1 +Nc1ccc2c(c1)NC(=O)C(Cc1ccccc1C(F)(F)F)O2 +CCOC(=O)c1cncc(C(=O)Nc2ccc(F)cc2)c1 +CC(NC(=O)c1ccc(N2CCCC2=O)cc1)c1ccco1 +CC(C1CC1)N(C(=O)c1nc(S(C)(=O)=O)n2ccccc12)C1CC1 +O=C(NCCNc1ncc(Cl)cc1Cl)N1CCC1 +O=C(COc1ccccc1)NCc1nc(-c2cccs2)no1 +Cc1noc(C)c1C(C)NC(=O)c1c[nH]nc1-c1ccc(Cl)cc1 +O=S1(=O)N=C(Nc2cc(Cl)cc(Cl)c2)c2ccccc21 +CCC(=O)c1ccc(F)c(S(=O)(=O)NC2CC2)c1 +Cc1nc(N2CCCCC2)ncc1-c1cc(=O)n(Cc2ccccc2)[nH]1 +O=C(NC(c1ccccc1)c1ccco1)C1CCOC1 +CCOc1ccc(NC(=O)c2ncoc2-c2cccs2)cc1 +CC(=O)NCC(=O)NCc1ccccc1Cn1cncn1 +COc1cccc2c1C(c1ccc(F)nc1)NCC2 +Cc1ccccc1C1(CNC(=O)c2cnc(C3CCCO3)s2)CC1 +CCCCN(CC)C(=O)Cc1noc2ccc(N)cc12 +Cc1nn2c(nnc3c(=O)[nH]c(=O)[nH]c32)c1-c1ccccc1 +CNC(=O)c1cc(Cl)ccc1NC(=O)C1CCOc2ccccc21 +O=C(c1ccc2[nH]ccc2c1)N1CCc2cc(F)ccc2C1 +N#Cc1ccc(NCc2ccc(-n3ccnc3)nc2)cc1C(F)(F)F +C=CCc1cc(C(=O)Nc2ccc(C(C)=O)cc2)cc(OC)c1OC +Cn1cc(C(=O)N=c2ccccn2Cc2ccccc2)ccc1=O +CC1CN(C(=O)Cn2nnc(-c3ccccc3Cl)n2)CC(C)O1 +CCCC1CN(C(=O)c2ccc(N3CCCCC3=O)cc2)CCO1 +CCCOc1ccc(-c2nc3sc(C4CC4)nn3c2C#N)cc1 +CCNC(=O)CSc1nc(-c2ccccc2F)n[nH]1 +C=CCNC(=O)c1ccc(NC(=O)NCc2cccc(OC)c2)cc1 +O=c1cc(CNC(c2ccccc2)c2ccccc2)[nH]c(=O)[nH]1 +COc1c(F)cc(NC(=O)NCc2cccs2)cc1F +O=C(Nc1cc(O)cc(F)c1)c1ccncc1F +CC(C)NC(=O)C1CCN(C(=O)Cc2cccc(OCC#N)c2)CC1 +Cc1ccc(-n2nc(CO)c(C(=O)NCc3ccc(F)cc3)n2)cc1 +CC(NC(=O)COc1ccccc1C(N)=O)c1ccccc1 +O=C(c1cc(C2CC2)on1)N1CCC(Oc2ncccc2Cl)CC1 +CN(C(=O)c1onc(-c2cccnc2)c1N)C1CCCCC1 +COCCNC(C)(C(=O)OC)c1cccc(O)c1 +COc1ccc(OC)c2c1C(=O)CC2C(=O)N1CCCCC1 +CCCC(=O)Nc1nn(C)c2nc3ccc(C)cc3cc12 +N#Cc1ccccc1CN1C(=O)COc2cc(CO)ccc21 +Nc1ncc(C(F)(F)F)cc1NCc1ccc(Cl)cc1 +CCC(C)NC(=O)C1CCC(c2ccc(F)cc2)N(C(C)=O)C1 +CC(=O)Nc1nc2ccc(C(=O)NCCO)cc2s1 +CC(C)(C)NC(=O)CSc1nnc(C2CC2)n1Cc1ccco1 +CCn1c(SCC(=O)Nc2cc(C)nn2C)nnc1-c1ccco1 +O=C1CC(c2c[nH]c3ccccc23)c2c(c3ccccc3[nH]c2=O)O1 +CC1CCC(N(C)C(=O)Cn2nnc3ccccc3c2=O)CC1 +CSc1ccc(CN2CCN(C(=O)c3cccc(F)c3)CC2)cc1 +CCCCS(=O)(=O)N1CCCC1c1ccncc1 +CCCCOC(C)C(=O)NC1(C)Cc2ccccc2C1 +CCNC(=O)CN1CCN(C(C)C(=O)N(C(C)C)C(C)C)CC1 +O=S(=O)(CCNS(=O)(=O)c1ccc(F)cc1)c1ccccc1 +CNC(=O)c1cc(NC(=O)NCc2ccco2)ccc1Cl +C#CCOc1cc(F)ccc1NC(=O)CCSc1ccccn1 +CC(C)(C)c1cc(NC(=O)c2csc(-n3cccc3)n2)on1 +O=C(NCC1CCCCC1)c1cc2c(cn1)OCC2 +COC(=O)Cn1c(CNC(=O)C2CCCCC2)nc2ccccc21 +CNc1nc(C2CCOc3ccccc3O2)cs1 +C=CCOc1ccccc1CN1CCOC(C(N)=O)C1 +O=C(NCCNC(=O)c1nc(-c2cccs2)no1)c1cnccn1 +COc1cccc(C(=O)N2CCC(Oc3cnccn3)CC2)c1OC +CCC(O)CN1CCN(C(=O)COC2CCCCC2)CC1 +CCC1CCCCN1C(=O)CNc1ccc(C(C)=O)cc1 +COc1ccc2c(C)c(C(=O)N(C)CCCC3CCCO3)oc2c1 +CC(C)(C(=O)NCCCCCO)c1ccc(N)cc1 +Cc1ccc(NC(=O)CCC(=O)NCCO)cc1 +c1ccc(-n2ccnc2SCCn2cccn2)cc1 +CCCc1nnc(NC(=O)C(CC(C)C)N2CCCCC2=O)s1 +CCc1noc(-c2csc(C(=O)NCc3ccc(F)cc3)n2)n1 +Cc1ccc(NC(=O)N2CCC(Oc3cnccn3)CC2)cc1C +Cc1cccc(C(=O)NC(C)c2nc3ccccc3n2CC(N)=O)c1 +Cc1ccc(CCNC(=O)NC(C)CCCO)c(C)c1 +Nc1cc(Cl)ccc1NS(=O)(=O)c1cn[nH]c1 +CC1CCCN(S(=O)(=O)NCCS(=O)(=O)c2ccccc2)C1 +Cc1ccc(C(C)NC(=O)Nc2ccccc2CN2CCOCC2)o1 +CCOc1ccc(CNC(=O)c2cc(C)nc(SC)n2)cc1 +CN(Cc1cccs1)S(=O)(=O)c1ccc(Cl)cc1F +FC(F)(F)c1cccc(Oc2ncccc2CNc2ncccn2)c1 +COc1cccc(-c2ncc(C(C)(C)O)s2)c1OC +O=C(NC1c2ccccc2CC1O)C1COc2ccccc2O1 +Cc1csc(CNC(=O)c2nn(-c3ccccc3)c(C)cc2=O)n1 +CN(C)C(=O)Cn1cc(C(=O)Oc2ccc(Cl)c(Cl)c2)nn1 +Cc1sc2nc(SC3CCCCNC3=O)nc(N)c2c1C +CCNS(=O)(=O)C1CCN(C(=O)c2c(C)[nH]c3ccccc23)C1 +CCN(Cc1ccncc1)S(=O)(=O)c1cn[nH]c1C +NC(=O)C1CCCCCC1NC(=O)C1CC=CC1 +CN(C(=O)c1cc2ccccn2c1)c1ccccc1 +COC(=O)C1=C(C)N(C)C(C)=C(C(=O)OC)C1c1ccsc1 +Cc1cc(NC(=O)C2CCN(C(=O)c3cccc(C)c3O)CC2)no1 +COc1cc2nc(-c3ccc4c(c3)OCO4)nc(N)c2cc1OC +CC(C)CCOc1ccccc1C(=O)N1CCN(CCC#N)CC1 +Cc1nn(C)c(C)c1C(C)NC(=O)c1ccnc(-n2cncn2)c1 +O=C(CC1Sc2ccccc2NC1=O)NCCCn1ccnc1 +CC(C)CC(=O)NCCNC(=O)c1ccc(Cl)c(Cl)c1 +O=C1CSc2ccc(COC(=O)CNC3CC3)cc2N1 +CCCCNS(=O)(=O)c1cccc(C(=O)NC2CCCC2)c1 +COCCc1ccc(OCC(=O)N2CCN(C(=O)C3CC3)CC2)cc1 +CCCC1CN(C(=O)Nc2cnn(C(C)C)c2)CCO1 +CC(=O)c1cnc2cc(-c3ccc(Cl)cc3)nn2c1C +Cc1cc(NC(=O)C(C)Sc2nnnn2C2CC2)on1 +CC(CO)NC(=O)Nc1cccc(-n2cccn2)c1 +COc1ccc(CC(=O)Nc2cccc(OC(C)=O)c2)cc1OC +Cn1cc(C(=O)N2CCN(Cc3cnc4ccccn34)CC2)nn1 +Nc1cc(Cl)ccc1NC(=O)Nc1ccccc1 +COC(=O)c1ccc(CN(C)C(=O)C2CC3CCC(C2)C3=O)cc1 +COc1ccc(CNC(=O)c2ccc(-n3cnnn3)cc2)cc1OC +CCN(CC(=O)NCc1ccc(F)cc1)C(=O)Nc1ccc(F)cc1 +CCCOC(=O)c1cc(-c2ccc(O)cc2O)nn1C +O=C(C1CC1)N1CC(c2nc(-c3cnccn3)no2)C1 +Cc1csc(=O)n1Cc1csc(-c2ccccn2)n1 +N#Cc1ccc(OS(=O)(=O)c2cccc(C(N)=O)c2)cc1 +O=C(Cn1ncc2ccccc21)NCc1cccnc1 +Cc1cc(C)c2c(OCC(=O)N3CCCCC3CCO)nn(C)c2n1 +CN(C(=O)c1cccc(Nc2cnn(C)c2)c1)c1ccc2c(c1)CCO2 +CC(=O)c1ccc(N2Cc3cnc(CC(C)C)nc3C2)nc1 +CCOC(=O)CCC(C)NC(=O)NC1(C)CCCCC1 +Cc1cc(NC(=O)NCc2scnc2C)ccc1C(=O)N(C)C +O=C(NCCOc1ccccc1C(F)(F)F)N1CCCC(CO)C1 +Cc1ccc(CCNC(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1 +C=CCN1CCc2cc(S(=O)(=O)N(CC)CC)ccc21 +COc1cc2nc(-c3ccc(C)c(N)c3)[nH]c2cc1OC +Cc1ccc(C)c(NC(=O)CCn2cc(-c3cccc(C#N)c3)nn2)c1 +CCOc1ccc2c(C(=O)Nc3ccc(Cl)cn3)cc(=O)oc2c1 +O=C(c1ccco1)N(Cc1cccc(Br)c1)C1CC1 +CC(C)CNC(=O)c1cccc(NC(=O)c2cc3ccoc3cn2)c1 +CC(c1ccccc1)N(C)C(=O)CC1OCCc2sccc21 +Nc1cc(C(F)(F)F)ccc1NC(=O)c1cccnc1 +C=CCn1c(=O)c(C#N)cc2c(=O)n3ccccc3nc21 +N#CC1(C(=O)Nc2cccc(Br)c2)CCCC1 +O=c1c(=Cc2ccccc2)sc2nc(-c3ccncc3)nn12 +CC(C)c1nncn1CCNC(=O)c1cccc(-c2ccoc2)c1 +COC(=O)c1ccc(C(=O)Nc2ccc(C)c(C)c2)cn1 +CC(=O)Nc1ccc(OS(=O)(=O)c2ccccc2C)cc1 +Cc1nc(CN2CCN(C(=O)Cc3csc(C)n3)CC2)no1 +CC1(NC(=O)C2CC(=O)N(c3ccc4c(c3)CCC4)C2)CCCC1 +COc1ccc(C)cc1CN1CCn2c(nnc2C2CC2)C1 +O=C1CC(C(=O)N2CCc3ccccc32)c2ccccc2N1 +CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccncc2)CC1 +N#Cc1cn(C2CC2)c(=O)n(Cc2nc(Cc3ccccc3)no2)c1=O +Cn1nnc2c(N3CCN(S(C)(=O)=O)CC3)ncnc21 +CCOc1ccccc1OCCN(C)c1ccccc1N +COc1c(C)cnc(CN(C)C(=O)c2cccnc2N(C)C)c1C +Cc1n[nH]c(C(=O)NCc2ccoc2)c1Br +CCn1cc(Br)c(C(=O)Nc2ccc(C)cn2)n1 +CN(CCOCC1CC1)C(=O)c1cnn(-c2ccccc2Cl)c1 +CCCOc1ccc(-c2nc3cc4c(cc3[nH]2)OCCO4)cc1N +CC(C)(CNC(=O)NCCc1ccccn1)c1ccccc1F +O=C(NCCNC(=O)C1CCN(C(=O)c2ccco2)CC1)C1CC1 +Cc1ccc(C)c(-n2c(SCC(N)=O)nnc2-c2cccnc2)c1 +Cc1cc(N2CCCC(c3ncncc3S(C)(=O)=O)C2)ncn1 +Cc1ccc(C)c(OC(=O)c2sccc2-n2cnnn2)c1 +O=C(CC1CCCO1)Nc1ccccc1-c1cccs1 +CCN(CC)C(=O)Nc1ccc(Oc2cccnc2)c(C)c1 +Cn1c(CCCNC(=O)C2CCCN(C(N)=O)C2)nc2ccccc21 +COCCOc1ncccc1NC(=O)NCc1cccs1 +CC(=O)c1ccc(NC(=O)c2csc(-n3cccc3)n2)cc1 +O=C(CC=Cc1cccc(F)c1)NCC(O)Cc1ccccc1 +CCOC(=O)c1cc(C(=O)N2CCOCC2)nn1C +O=C(NCCN1CCOCC1)N(CCc1cccc(F)c1)C1CC1 +CC(NC(=O)c1ccc(S(N)(=O)=O)cc1)c1cccc(Cl)c1 +CCOCCNC(=O)N(Cc1ccc(F)cc1)C1CC1 +NC(=O)c1ccc(NC(=O)c2c[nH]c3ccccc3c2=O)cc1F +CC(=O)Nc1ccc(NC(=O)c2ccc(-n3cc(C)cn3)cc2)cc1 +COc1ccc(Oc2ncnc(Nc3nc(C)c(C)s3)c2N)cc1 +Fc1ccc(C2=Nn3c(CN4CCOCC4)nnc3SC2)cc1 +Cc1cncnc1C1CCN(S(=O)(=O)c2cn(C)cn2)CC1 +Brc1ccccc1OCc1nc(-c2ccncc2)no1 +C=C(C)CN(CC)C(=O)CSc1nc2sccc2c(=O)n1C +CC1CN(Cc2nc3ccsc3c(=O)[nH]2)CC(C)O1 +CCn1c(C2CCN(C(=O)NCCCOC)C2)nc2cccnc21 +CCOc1ccc2c(c1)S(=O)(=O)N=C(NCCCOC)N2 +COC(=O)c1cc(S(=O)(=O)NCc2ccc(OC)cc2)c[nH]1 +Cc1cc(C(=O)Nc2nnc(Cc3ccc(C)c(C)c3)o2)n(C)n1 +Cc1ccc(C(=O)N2CCCN(Cc3cccs3)CC2)cn1 +Cc1n[nH]c(-c2ccc(NS(=O)(=O)NCc3ccccc3)cc2)n1 +O=C(NCCCn1cccn1)c1nn2ccccc2c1Cl +O=C(Nc1ccccc1)C1CCN(C(=O)c2ccncc2)CC1 +CC(NC(=O)c1[nH]ncc1Br)c1ccc2c(c1)CC(=O)N2 +Cc1ccc(CC(=O)Nc2ccc(=O)n(C)c2)s1 +Cc1nc2n(n1)CCCC2NC(=O)NCCCc1ccccc1Cl +CN(C)C(=O)C1CCN(CC(C#N)CCC#N)CC1 +CC1Cc2ccccc2N1C(=O)Cn1cc(C#N)c2ccccc21 +Cc1cc(OCC(=O)OCC2CC(=O)N(C3CC3)C2)ccc1Cl +Cc1ccccc1NC(=O)N1CC(O)C(N(C)Cc2cnccn2)C1 +COc1ccc(Br)c(C(=O)Nc2ccc(F)c(N)c2)c1 +Cc1ccc(OC(C)C(=O)Nc2cc3c(=O)[nH]cnc3cc2F)cc1 +COCc1ccc(NCCCc2ccc(C)o2)cc1 +C#CCNC(=O)NC(C)c1cccc(N2CCCC2)c1 +CCC(Oc1ccccc1OC)C(=O)N1CCN(C)CC1 +Cc1ccc(S(=O)(=O)NC2CC2)cc1C(=O)Nc1cc[nH]n1 +Cc1ccc(-c2ccnc(NC3COCC3N3CCCC3)n2)c(C)n1 +Cc1csc(C2CCCN(C(=O)C(C)OCC(F)(F)F)C2)n1 +O=C(NCC1Cc2ccccc21)N1CCN(Cc2ccccn2)CC1 +CN(C)C(=O)C1CC(=O)N(c2ccccc2F)C1 +CCOc1ccc(C(=O)Nc2nc(-c3cccc(O)c3)cs2)cc1 +Cc1cn(CC(=O)N(C)Cc2cn(C)nc2C)nc1N +Cc1cc(NC(=O)c2ccco2)sc1C(=O)Nc1cnn(C)c1 +CCCn1nc(C)cc1NC(=O)c1ccc(C#N)cc1 +CCc1nn(C)c(OC)c1CN(C)C(C)CC#N +COC1C(C(O)CO)OC2OC3(CCCCC3)OC21 +Cc1cccc(S(=O)(=O)Cc2noc(C)n2)c1 +O=C(c1ccc(F)cc1Cl)N1CCCC1Cn1cccn1 +Cn1cc(Br)cc1C(=O)N1CCC(C(N)=O)CC1 +CCCc1nnc(NC(=O)N2CCN(CC(=O)NCC)CC2)s1 +O=C(NC1CC1)c1c(-n2cnnn2)sc2c1CCC2 +Cn1nnc2cc(NC(=O)Nc3cccc(Cl)c3)ccc21 +COc1ccccc1-n1c(=O)n2n(c1=O)CCCC2 +CN(Cc1ncnn1C)C(=O)NCc1ccnc(OC(C)(C)C)c1 +Cc1cccc(NC(=O)C2CSc3nccc(=O)n3C2)n1 +O=c1n(CCn2nnc(-c3cccs3)n2)nc2ccccn12 +c1cc(-c2nc3c(c(Sc4nnnn4C4CC4)n2)CCC3)ccn1 +Cc1cccc(C(CNC(=O)Cc2ccc[nH]2)N2CCOCC2)c1 +NC(=O)c1ccsc1NC(=O)c1ccc(-c2ccccc2)cc1 +Cc1nc(C(=O)N2CCN(C)c3ccccc3C2)nn1-c1ccccc1 +CC(=O)Oc1ccc(Oc2ccc(OC(C)=O)cc2)cc1 +CC(C)c1ccc(NC(=O)CCn2cnc3c(cnn3C)c2=O)cc1 +c1cnc(N2CC(OCc3ccncc3)C3OCCCC32)nc1 +NC(=O)c1c(NC(=O)c2cccc(F)c2)sc2c1CCC2 +Cn1nccc1CSc1cc(C(=O)NC2CC2)c2ccccc2n1 +O=C(c1ccsc1)N1CCN(Cc2nnc(C3CC3)o2)CC1 +Nc1cc(F)cc2c(NCCc3ccccc3)nccc12 +CCOc1ccccc1OCc1noc(-c2ccc(OC)cc2)n1 +CC(Oc1ccc(F)c(F)c1)C(=O)Nc1cnn(CC(F)(F)F)c1 +CCCN1CCN(C(=O)c2cc(-c3ccco3)n[nH]2)CC1 +CCCCNC(=O)C1CC(=O)N(c2n[nH]c3cccc(F)c23)C1 +COCC(=O)Nc1ccc(CC(=O)NC2CC2)cc1 +NC(=O)COc1cccc(COC(=O)C2CC=CCC2)c1 +CC(C)CCc1nc(CSc2nncn2C)cs1 +COc1ccc(CCC(=O)Nc2cccn(C)c2=O)cc1F +CC(CC(=O)N1CCC(N2CCCC2=O)CC1)Cc1cccc(F)c1 +CC(NS(=O)(=O)c1cn[nH]c1)c1ccc(F)c(F)c1 +CN1CCN(C(=O)c2csc(-c3cc4ccccc4[nH]3)n2)CC1 +Cc1nn(C)c(=O)c(C(=O)NCc2cccc(OC(F)F)c2)c1C +O=C(CN1CCN(CCO)CC1)N(C1CCCC1)C1CC1 +Cc1[nH]nc(C(=O)NC2CCC(C(N)=O)CC2)c1N +Cc1cc(=O)oc2c3c(ccc12)OCN(CCCN1CCCC1=O)C3 +Cc1ccc(C(=O)CN2C(=O)c3ccccc3S2(=O)=O)cc1C +Oc1cccc(CN2CCN(c3cncc(-n4cccn4)n3)CC2)c1 +Cc1ccc(NC(=O)C2COc3ccccc3O2)c(F)c1 +CCN(CC)S(=O)(=O)c1cc(N)c(OC)c(OC)c1 +CCC(C)NC(=O)CCN(CC)C(=O)c1ccoc1C +CC(=O)NCC1CC(=O)N(c2ccc(Cl)cc2)C1 +COc1ccc2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)[nH]c2c1 +Cc1noc(COC(=O)C2CCN(c3ccc(Cl)cn3)CC2)n1 +Cc1cccc(NC(=O)NCC(c2cccs2)N2CCOCC2)c1 +CC(CC(=O)NC1CCN(c2ncccn2)CC1)c1cccc(F)c1 +CCOc1ccc(-c2nn3c(-c4ccccn4)nnc3s2)cc1 +O=C(Nc1ccc(F)c(F)c1)c1ccc(-c2ccccc2)[nH]c1=O +CC(C)OCCC(=O)N1CCc2cc(F)ccc2C1 +Cc1ccccc1-n1ccnc1SCCN1CCOC1=O +CCC(=O)N1CCc2cc(C(=O)Cn3ccc(C)c(C#N)c3=O)ccc21 +CC(C)Oc1ccc(NC(=O)Cn2cnnn2)cc1 +COC(=O)Cn1nc(-c2ccccc2F)c2c1CCNC2 +CC(=O)N1CCc2cc(C(=O)Nc3ncccc3O)ccc21 +Cc1cc(C)cc(C(C)NC(=O)Cc2ccc(-n3cnnn3)cc2)c1 +COc1cccc(-c2cnnc(NC(C)CCn3cccn3)n2)c1 +COc1ccccc1CNc1nnnn1-c1ccccc1 +OCc1nnn(Cc2ccccc2)c1-c1ccncc1 +CC1CCC(NC(=O)c2cc(S(C)(=O)=O)ccc2Cl)CC1 +COc1ccc(C(=O)Nc2cc(N3CCCC3)ncn2)c(OC)c1 +COc1ccc(-c2ccc(C#N)c(=O)[nH]2)c(OC)c1OC +CCN(CC)C(=O)c1ccc(N2CCNC2=O)c(C)c1 +Cc1nn(Cc2ccccc2F)c(C)c1NS(C)(=O)=O +CCCCCC(=O)N1CCN(c2nnnn2-c2ccccc2)CC1 +Cc1csc(NC(=O)c2nc(-c3cnccn3)no2)n1 +CCOC1CCCN(C(=O)c2cc(-c3cccnc3)on2)C1 +C#CCOc1ccc(N(C)C(=O)c2cnn(-c3ccncc3)c2C)cc1 +COC(=O)c1sc(NC(=O)c2cc(C)ccc2C)nc1C +O=C(NCCCn1cncn1)c1cc(Br)ccc1F +CC(C)(C)NC(=O)CC1(C(=O)Nc2ccc(F)cc2)CCCC1 +NC(=O)CCCNC(=O)Cc1ccc(N2CCCC2=O)cc1 +OCc1ccc(Br)cc1-n1cccn1 +CCCCCCNC(=O)N1CCCN(C(=O)CC)CC1 +COC(=O)c1ccc(-c2nc(CSc3nc(C)n[nH]3)cs2)cc1 +Cc1ccc(-c2csc(CC(=O)NCc3ccccc3)n2)s1 +COCc1ccc(CNC(=O)NC(C)C(=O)N2CCCCC2C)cc1 +O=C(NCCn1cccc1)c1c[nH]nc1-c1c(F)cccc1F +Cc1cc(CN(C)C(=O)Nc2ccc3[nH]c(C(F)F)nc3c2)no1 +Cc1cccc(OCCNC(=O)CC2C=CCC2)c1 +COc1ccccc1NC(=O)CCCC(O)c1cccs1 +COCC(C)N1CCN(C(=O)COCC2CCCO2)CC1 +CCN(CC)C(=O)Cn1ccc2ccc(C(=O)OC)cc21 +Cc1ccc(-c2ncco2)cc1NC(=O)CCCCNC(N)=O +CC(=O)Nc1ccc(S(=O)(=O)NCC#Cc2ccc(F)cc2)cc1 +CCOc1nc(COC)nc(NC(C)(C)C)c1N +Clc1ccc2c(c1)CCNC2c1cncs1 +Cc1cc(C#N)ccc1OCCc1scnc1C +O=C(NCc1ccco1)c1cccc(NC(=O)c2cccs2)c1 +N#Cc1cccc(N2CC3c4ccccc4OCC3(CO)C2)n1 +Cn1ncc(Cl)c1-c1nn2c(-c3cnccn3)nnc2s1 +NC(=O)COc1ccccc1C(=O)NCc1nnc2ccccn12 +Cc1cc(C(=O)Nc2ccc3c(c2)OCCCO3)no1 +CCOC(=O)CN(C(=O)c1cc(C(C)=O)c[nH]1)C(C)C +CNC(=O)c1cnc(CCc2ccccc2)nc1N +CCOc1ccc(-c2nnc3ccc(F)cn23)cc1N +Nc1nonc1C(=O)NCCNC(=O)c1ccc(Cl)cc1 +Cc1ccc(C)c(-n2c(C)nnc2SCC(=O)NC(C)(C)C)c1 +Cc1ccncc1NC(=O)C(C)Oc1ccccc1Br +CCCC(C)CC(=O)NC(C)c1c(C)noc1C +O=C1N=CC(CCC(=O)OCC(=O)Nc2ccccc2)=N1 +CCOc1cc(Cl)c(C(=O)CC)cc1OCC +CC(C)c1ccc(OCCNC(=O)c2cc(C(N)=O)cs2)cc1 +O=C(NC1C2CCC(C2)C1CO)c1nc2ccccc2c(=O)[nH]1 +COCC(C)NC(=O)NC1CCN(C(=O)c2ccccc2O)CC1 +COc1ccccc1OCC#CCNC(=O)C1CCCC1 +CCN1CCN(S(=O)(=O)c2cc(OC)c(C)cc2OC)CC1 +CCC(C)NC(=O)CCNC(=O)Nc1ccnn1C1CCCCC1 +COc1ccc(NC(=O)CNc2cc(F)cc(F)c2)cc1 +COCCn1c(SCC(=O)OC)nc2c1c(=O)[nH]c(=O)n2C +CCC(C)(C)NC(=O)C(C)N1CCc2cc(F)ccc2C1 +COc1cc(F)c(C(=O)Nc2ccc3c(c2)COC3)cc1OC +CC(C)NS(=O)(=O)c1ccc(C(=O)N(C(C)C)C2CCC2)cc1 +O=C(CS(=O)(=O)c1nc2ccccc2[nH]1)NC1CC1 +O=C(OCCNc1ncccn1)c1cccc(Br)c1 +Cc1cccc(NCC(=O)NCc2cccs2)c1C +Cc1noc(COc2ccc(NC(=O)C3CC(=O)N(C)C3)cc2)n1 +CN(C)c1ccc(C(=O)NCCNC(=O)c2ccccc2O)cc1 +Cc1nn(C)c2nc(NC(CO)CC(C)C)sc12 +CN(C1CC1)S(=O)(=O)c1ccc(S(C)(=O)=O)cc1 +N#Cc1ccc(COC(=O)c2ccc3c(c2)OCC(=O)N3)cc1 +COc1cc(Cl)c(C)cc1NC(=O)Cn1ccnc1 +CC(C)Cn1nc(CO)cc1-c1cc(F)ccc1F +Cc1[nH]ncc1C(=O)NC(C)(C)c1ccc(Cl)c(Cl)c1 +CCCc1nc(C)c(C(=O)Nc2ncccc2O)s1 +CCc1cc(N2CCCC(Cn3cncn3)C2)nc(-c2ccncc2)n1 +CC(NC(=O)Nc1nc2ccccc2s1)c1cccnc1 +CC(C)c1cc(C(N)=O)c(NC(=O)c2ccc(F)c(F)c2)s1 +CC1(C)C2CCC1(C)C(NC(=O)Cc1ccc[nH]1)C2 +Cc1ccccc1NC(=O)CN(C)S(C)(=O)=O +CCC(C)Sc1nnc(-c2cn(C)nc2OC)n1CC +COc1ccc(OC)c(C(O)CNCc2cccc(O)c2)c1 +O=C1C(Sc2ncn[nH]2)CCN1c1ccccc1 +O=C(Nc1ccc(OCC2CCCO2)cc1)c1csnn1 +O=C(Cn1ncc2ccccc2c1=O)NCCCC1CCCC1 +CCC(CC)C(=O)NC1CCN(c2c(F)cccc2F)C1=O +CC(C)(C)OC(=O)N1CCC(Oc2c(F)ccc(F)c2F)CC1 +COCC(C)NC(=O)CCCn1cnc2c1c(=O)n(C)c(=O)n2C +CC(C)c1ccccc1OCCCN1CCCC1=O +CC1CC(C)CN(S(=O)(=O)Nc2cccc(S(N)(=O)=O)c2)C1 +CC(NC(=O)c1ccc(N(C)C)c(F)c1)c1nnc2ccccn12 +COC(=O)CSc1nnc(-c2ccc(F)cc2)n1C +CCOc1ccc(NC(=O)c2ccc(F)nc2)cc1C +CCCc1nc(-c2nc(-c3cccnn3)no2)cs1 +COc1ccc(C)cc1NC(=O)c1cccc2[nH]ccc12 +COc1ccccc1OCC(=O)Nc1cccc(-c2nccc(C)n2)c1 +Nc1ccc2c(c1)sc1nc(-c3ccc(F)cc3)cn12 +COc1cc(N)ccc1-c1nc(C)cc(C(C)C)n1 +Cc1ccc2[nH]c(C(=O)N3CCOCC3C3CC3)cc2c1C +CCNC(=O)NCCC(=O)N(C)Cc1ccccc1Br +NC(=O)c1nn(-c2ccc3ccccc3n2)c2c1CNCC2 +O=C(CCS(=O)(=O)c1ccccc1)N1CCCCC1 +COC(=O)CCNC(=O)c1c(-c2c(F)cccc2Cl)noc1C +C#CCOc1cc(F)ccc1NCc1ccc(S(C)=O)cc1 +COC(=O)C1CC(O)CN1Cc1cnc(C(C)C)s1 +O=C(Nc1ccc2c(c1)CCC2)N1CCC(Oc2ccccc2)CC1 +CSc1ccsc1C(=O)Nc1ccc(N2CCNC(=O)C2)nc1 +O=C(c1cnn(-c2ccccc2)c1)N1CCc2cc(F)ccc2C1 +Cc1noc(CCC(=O)NC(C)(C)c2nc(C)c(C)s2)n1 +COCCNc1cc(C)c(C#N)c2nc3ccccc3n12 +C=CCn1c(CNC(=O)c2cccc(OC)c2)nc2ccccc21 +Cn1cccc1C(=O)NCCSc1ccc(Cl)cc1 +CC(O)CC(C)CNC(=O)NC1CCN(CC(F)(F)F)C1=O +CCC(C)(C)NC(=O)CN1C(=O)COc2ccccc21 +CCOc1ccc(Oc2nc(NC3CC3)nc(N(C)C)n2)nn1 +COCc1nnc(-n2nnc(C#N)c2-c2ccncc2)s1 +Cc1nc(CNC(=O)COc2c(C)cccc2C)no1 +Cc1ccc(NC(=O)COC(=O)c2ccc(N)cc2)c(C)c1 +CCC(C)(CNC(=O)CCc1c(C)nn(C)c1C)N1CCOCC1 +CC1(C(=O)NCCc2c[nH]c3ccccc23)CC1(Cl)Cl +CCOC(=O)N1CCN(C(=O)Nc2cccnc2OCC)CC1 +C#CCN(Cc1ccc(F)cc1)Cc1cn(C)nc1-c1ccncc1 +CCN(CC)c1c(Br)cc(C(C)=O)n1C +Cc1cc(C)nc(N2CCC(c3nc4ccccc4[nH]3)CC2)n1 +CCOCc1ccccc1NC(=O)N(C)Cc1ccc(OC)cc1 +Cc1cc(S(N)(=O)=O)c(C)cc1Br +COCC1CCCN(C(=O)c2cc(Cc3ccccc3)no2)C1 +C=CCN(CC=C)C(=O)c1ccc(NC(=O)c2cnn(C)c2)cc1 +O=C(CSc1nnc(-c2ccc(O)cc2)o1)c1ccc(F)cc1 +CCN(CC(=O)OC)C(=O)COc1ccc(Br)cc1 +Brc1ccnc(N2CCCCCC2)c1 +O=C(Nc1cccnc1)N1CCC(O)(C(F)(F)F)C1 +CCN(Cc1ccco1)C(=O)NCc1ccnc(-n2cccn2)c1 +CCN(CC)C(=O)CCC(=O)N1CCCc2cc(Cl)cc(C)c21 +CC(=O)NCc1nc2ccccc2n1Cc1cccc(C)c1 +CC(=O)N(CCc1ccccc1)CC(=O)NCC(C)(C)O +Cc1cccc(C)c1NC(=O)c1ccc(-n2nnc3cccnc32)cc1 +N#Cc1ccc(NCC2Cc3ccccc3O2)c(F)c1 +COCC1(NC(=O)Cn2cccnc2=O)CCCC1 +C=CCN(C)C(=O)c1ccc2c(=O)n3c(nc2c1)CCCC3 +Cc1ccc(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)s1 +O=C(c1ccncc1)N1CCC(Oc2cccc(F)c2)CC1 +CC(C)c1cccc(NC(=O)NCc2ncn(C)n2)c1 +CC(C)OC1CCC(NC(=O)CC(O)C(C)C)CC1 +Cc1ccccc1Cc1nc(CNc2ccc(-n3cncn3)cc2)no1 +CC(C)(C)OC(=O)C(C)(O)CNC(=O)c1cc(C#N)c[nH]1 +O=C(CCC1CCCCC1)N1CCC(c2nnc(C3CC3)o2)CC1 +CCSc1nnc(NC(=O)CCNC(C)=O)s1 +O=C(Nc1nc2c(s1)COCC2)c1ccc2[nH]ccc2c1 +O=C(Nc1ccc(Oc2cccnc2)nc1)c1n[nH]c2ccccc12 +Cc1nc(COc2ccccc2)[nH]c(=O)c1CCO +Cc1cnn(CCC(=O)Nc2ccccc2N(C)C)c1 +Cc1nc(CCNC(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)cs1 +CN(C(=O)c1ccn(-c2ccccc2Cl)n1)c1nccs1 +COC(=O)c1sc(NC(=O)c2cc(C)sc2C)nc1C1CC1 +N#Cc1ccc(-c2noc(-c3cc(F)c(F)cc3F)n2)nc1 +Cc1ccc(SC(C)C(=O)c2ccc3c(c2)NC(=O)CO3)cc1 +Cc1noc(C)c1CCC(=O)NC1CCN(C(=O)c2ccoc2)CC1 +Cc1oc(-c2cccs2)nc1Cn1ccnc1-c1cnccn1 +Cc1noc(C)c1C(C)NC(=O)CCC(C)(C)C +CCOc1cc(NCc2ccc(OC)cc2)nc(C)n1 +CC(C1CC1)N(C(=O)Nc1ccccc1N1CCCC1=O)C1CC1 +O=S(=O)(N1CCCCCC1)n1nnc2ccccc21 +CC(C)(CNC(=O)N1CCOCC1)c1ccccc1 +COc1ccccc1CNC(=O)CCn1cc(Cl)cn1 +COCC(=O)Nc1cccc(-n2ccnc2-c2cc(C)c(C)o2)c1C +O=C(Nc1nnc(Cc2ccccc2F)s1)c1ccco1 +O=C(Nc1cn[nH]c1)N1CCCCC1Cc1ccccc1 +COc1ccc(CNC(=O)C2CNC(=O)N2)c(C(F)(F)F)c1 +CCOC(=O)CCCn1c(=O)c2cccn2c2cccnc21 +Cc1occc1C(=O)NCCOc1cccc(N)c1 +O=C(NCCc1nc[nH]n1)c1c(F)c(F)cc(F)c1F +Cc1cc(C)c(C(=O)Nc2ccc(NC(=O)NC3CC3)cc2)c(=O)[nH]1 +CCCn1c(=O)[nH]c(=O)c2c1nc(C)n2CCOC +CCc1nc(CCNC(=O)c2ccc(-c3ccccc3Cl)o2)no1 +O=C(Nc1cnn(Cc2ccccc2Cl)c1)C1CCC1 +Cc1nc(C)c(C(=O)Nc2sc(C)c(C)c2C#N)s1 +CCOC(=O)CC(C)NC(=O)Nc1cc(Cl)ccc1Cl +COc1ccc(OC(C)C(=O)Nc2cccc(N)c2)cc1 +Cc1cc(NCc2ccc(F)cc2F)ccc1C(=O)N(C)C +O=C(c1ccsc1)N1CCC(CO)(CCc2ccccc2)CC1 +Cc1cccc(CN(C(=O)NCc2cnn(C)c2)C2CC2)c1 +Cc1cc2nnc(SC(C)C(=O)c3ccc(F)cc3F)n2c(C)n1 +CC(=O)Nc1cc(C(=O)COC(=O)c2ccccc2Cl)ccc1O +CCC1OC(=O)c2c(OC)ccc(Br)c21 +O=C(NCc1ccccn1)NC(CO)Cc1c[nH]c2ccccc12 +CC(C)(C)OC(=O)N1CCC(Oc2ccc(C#N)cc2)CC1 +COc1cc(CC(=O)Nc2ccc(Cl)cn2)cc(OC)c1OC +Cc1ccc(F)c(OCC(=O)c2cc(C)[nH]c2C)c1 +Cc1ccc(-n2nnc(C#N)c2-c2ccc(F)c(F)c2)cc1 +CCc1cccc(-n2c(SCCC#N)nnc2N2CCOCC2)c1 +CC(C)(C)Oc1cc(CNC(=O)c2ccc3c(c2)OCO3)ccn1 +Cn1cc(C2CCCN2C(=O)c2ccc3c(c2)[nH]c(=O)n3C)cn1 +O=C(NC(CC(F)(F)F)c1ccc(F)cc1)c1cc(F)ccc1F +Cc1ccoc1C(=O)Nc1ccc(N2CCCC2=O)cc1 +Cc1ccc(CNS(=O)(=O)c2ccc3c(c2)CCC3)s1 +CN1CC(NC(=O)c2ccc(Br)cc2)CCC1=O +CN(CC1CC1)C(=O)c1cnc2sccn2c1=O +COc1ccccc1CCC(=O)N(C)Cc1nc(C)c2ccccc2n1 +CCC(CC)CN(CC)C(=O)Nc1ccc(F)c(C(=O)NC)c1 +CC(C)NC(=O)CN1CCN(C(=O)Cc2ccccc2F)CC1 +O=C(COC(=O)c1cc(=O)c2ccccc2o1)Nc1ccccc1 +Cn1cc(CNC(=O)NCCOc2ccc3c(c2)CCC3)cn1 +O=C(c1ccc(=O)[nH]c1)N1CCCc2ccccc21 +O=C(CCO)N1CCC2(CCCN(CC3CCC3)C2=O)C1 +CC(C)(C)OC(=O)N1CCCC2(C1)C(=O)NCC2c1ccccc1 +COCCOc1cccc(C(=O)N2CCCCC2Cn2cccn2)c1 +Cc1ccccc1NC(=O)Cn1nnc(-c2ccccc2Cl)n1 +Cc1cnc(N2CC(c3ccccc3)C3(CCNC3=O)C2)nc1 +Cc1cccc(CCNS(=O)(=O)Cc2ccccc2)c1 +CS(=O)(=O)N1Cc2ccccc2C2(CCN(C(=O)CC#N)CC2)C1 +CC1CN(C(C)C(=O)Nc2ccc3c(c2)OCCCO3)CC(C)O1 +CC(C)N(C(=O)c1ccc(S(=O)(=O)C(F)F)cc1)C1CCC1 +O=C(c1ccc(OCC(F)(F)F)nc1)N1CCOCC1 +COc1ncccc1C(=O)N1CCCC1c1nc(C)no1 +CC(=O)c1c(C)[nH]c(C(=O)OCc2nc(C(C)C)no2)c1C +CCCC(=O)Nc1nc(-c2ccc(CNC(C)=O)s2)c(C)s1 +CS(=O)(=O)N1CCC(C(=O)NCCC(O)c2cccs2)CC1 +CC(=O)c1cccc(OCCCC(=O)Nc2c(C)cccc2C)c1 +CN(CC(C)(C)O)C(=O)c1cccc(OCC(F)F)n1 +O=C(CSc1nnc(-c2ccccn2)o1)Nc1cccc(F)c1 +O=C(NCc1ccccc1Cn1cncn1)c1ccncc1 +COC(=O)C1CCCN(C(=O)c2cnc(C3CCCO3)s2)C1 +O=C(COC(=O)c1c[nH]c2ccccc12)NCc1ccccc1 +CC(C)n1nccc1NC(=O)c1ccc(Cl)cc1N +O=C(CNC(=O)c1ccccc1)NCC1COc2ccccc2O1 +Cc1nc(C)c(CNC(=O)N2CCc3ccccc3C2CO)s1 +Cc1ccc(O)c(NS(=O)(=O)c2ccc(F)cc2F)c1 +COc1ccc(-c2cnn(C)c(=O)c2C#N)cc1C +CSc1ccc(N2CC(C(=O)NC(C)(C)C)CC2=O)cc1 +Cc1n[nH]cc1NC(=O)c1ccc(Cl)cc1Cl +Cn1cc(C(=O)NCc2nc(C(F)(F)F)cs2)c(C(C)(C)C)n1 +Cc1nonc1NC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1 +COCCn1cnnc1SCC(=O)Nc1nc2ccccc2s1 +O=S(=O)(Nc1ccccc1Cn1cccn1)c1ccccc1F +O=C(Nc1ccnc2ccnn12)c1cc(F)cc(Br)c1 +CC(C)NC(=O)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +C=CCn1c(CO)nc2cc(Br)ccc21 +COc1ccc2c(c1)CCN2C(=O)c1cnc2[nH]nc(C)c2c1 +COc1cc(CC(=O)N2CCc3ccc(F)cc32)cc(OC)c1OC +CN(C(=O)COc1cccc(-c2csc(N)n2)c1)C1CCCCC1 +CN(C)c1ncc(-c2nc3cc(Cl)ccc3o2)cn1 +CCc1c(C)sc2nc(CC(=O)Nc3ccccc3C)[nH]c(=O)c12 +COC(=O)CCCn1c(CCO)nc2cc(N)ccc21 +Cc1cc(C(=O)NCC(=O)NC(C)c2c(C)noc2C)c(C)o1 +CC(C)CN1CC(C)(C)Oc2ccc(C(=O)CN)cc21 +CC(=O)c1ccc(F)c(S(=O)(=O)NCC(C)C)c1 +O=C(NCCNC(=O)c1cc2cnsc2s1)c1ccccc1 +CC(C)(C(=O)N1CCOC(C(N)=O)C1)c1cccc(C(F)(F)F)c1 +O=C(CCNC(=O)c1cccs1)NCCc1c[nH]c2ccccc12 +CCCCOC(=O)N1CCc2c(nc(-c3cccnc3)[nH]c2=O)C1 +O=C(c1csnn1)N1CCCCc2ccccc21 +O=C(NCCC(=O)N1CCC(c2ccc(O)cc2)CC1)c1ccoc1 +CC(C)CCNC(=O)C1CCN(C(=O)Cc2cccs2)CC1 +Fc1cccc2[nH]c(CN(Cc3cccnc3)Cc3ccco3)nc12 +CNC(=O)C1CCCCN1S(=O)(=O)c1cccnc1 +COc1ccccc1CCNC(=O)CN1CCCC1C(F)(F)F +COC(=O)CSc1nc2c(c(=O)[nH]c(=O)n2C)n1C(C)C +CCN(CCc1ccccc1)C(=O)Nc1cccnc1-n1cncn1 +CC(CO)NC(=O)Nc1cccc(S(=O)(=O)C2CCCC2)c1 +Cc1cccc(C(=O)NC(C)C(=O)N(C)Cc2ccc(Cl)cc2)c1 +O=S(=O)(NCc1cccnc1)c1cccc(F)c1 +COc1ccc(-c2nc(C)c(C(=O)N(C)C)s2)cc1OC +COc1ccc(CC(=O)NCCSc2c[nH]c3ccccc23)cc1 +Brc1cccc(CNc2cnn(-c3ncccn3)c2)c1 +Cc1cc(NC(=O)c2cccc3ccccc23)[nH]n1 +CCN(CC(=O)NC(C)C)C(=O)c1ccc(C)cc1 +Cn1ncc2c(N3CCC4CCCCC4C3)ncnc21 +Cc1ccnc(-c2ccc(NC(=O)NC3CCCCC3CO)cc2)n1 +Cc1nn(C)c(C)c1CCC(=O)NC1CCCCC12OCCO2 +CCC(C)c1noc(C2CCCN(C(=O)c3ccc(OC)cc3)C2)n1 +COc1ccccc1CN1C(=O)C(O)c2ccccc21 +O=C1CCC(C(=O)N2CCc3cc(F)ccc3C2)N1 +N#Cc1ccc(OCC(=O)N2CCN(Cc3ccccc3)CC2)cc1 +CCn1cc(Br)cc1C(=O)N(CCO)CC(F)(F)F +CCCn1c(CCNC(=O)c2ccncc2)nc2ccccc21 +O=C(Cc1cn2ccsc2n1)Nc1ccc[nH]c1=O +CCOCC1CCC2C(CCN2C(=O)c2ccnnc2)O1 +O=C(Cn1cnnn1)Nc1ccc(OC(F)F)c2ncccc12 +CC(C)CN(C)S(=O)(=O)c1cc(N)ccc1F +CC1(C)CN(C(=O)c2ccc(C(N)=O)cn2)c2ccccc2S1 +Cc1ccc(N2CCC(C(=O)NCCc3cnn(C)c3)C2=O)cc1 +O=C(Cn1cccn1)Nc1nc2ccccc2s1 +CCOc1ccc(C(=O)Nc2cccc(O)c2)cc1OC +CC(C)n1ccc(=O)nc1SCc1cccc(Br)c1 +Cn1cc(CNS(=O)(=O)c2cccc(C#N)c2)cn1 +CC(=O)NCCNC(=O)NCC1(N2CCOCC2)CCCCC1 +CCOC(=O)CN(C)C(=O)c1ccc(Br)cc1F +O=C(OCCC(F)(F)F)c1ccc(-n2ccnc2)cc1 +O=C(NC1c2ccccc2CC1O)c1cc(-c2ccncc2)on1 +O=c1c2ccccc2ncn1CCOc1ccccc1F +CCOC(=O)CSc1nnc2c3ccccc3n(C)c2n1 +COc1ccc(S(=O)(=O)NCC(=O)N2CCc3ccccc32)cc1 +CCn1ncc(Cl)c1C(=O)NC1CC(C(=O)OC)N(C)C1 +CCn1c(=O)n(CC(=O)NCc2cccc(Cl)c2)c2ccccc21 +CCNC(=O)CCc1nc(CC(=O)Nc2ccc(C)cc2)no1 +CC1(C)CN(C(=O)c2cc(-c3ccccc3)[nH]n2)CCO1 +Cc1nc(C(=O)N2CC3COCC3(COc3cccnc3)C2)cs1 +COc1ccc(C)cc1NS(=O)(=O)c1ccc2[nH]c(=O)oc2c1 +CC(C)c1nc(CS(=O)(=O)c2ccccc2Cl)cs1 +CC(C)(C)n1cc(C(=O)N2CCC(COc3ccccc3)CC2)cn1 +O=C(COc1ccc(Br)cc1)N1CCOCC1 +COc1ccnc(NC(=O)COc2ccccc2F)c1 +CCCS(=O)(=O)Nc1ccc2c(c1)N(C(=O)c1cccnc1)CC2 +Cc1nc(N2CCCC2)c(C#N)c2c1COC(C)(C)C2 +Cc1n[nH]c(-c2cccc(CNC(=O)c3coc4ccccc34)c2)n1 +CCn1c(Cn2nc(C)c(C)c(C#N)c2=O)nc2c(F)cccc21 +COC(=O)c1ccc2c(c1)NC(=O)c1ccccc1S2 +CC1=C(C(=O)Nc2ccccc2C)C(c2ccnn2C)n2ncnc2N1 +COc1ccc(-c2nnc(CC(=O)NCc3ccccn3)o2)cc1 +COc1cc2c(c(OC)c1OC)C(c1ccccc1C)CC(=O)N2 +CN(C)C(=O)c1ccc(-c2ccccc2Br)n1C +Cc1cccc(OCCNC(=O)c2cccc(N(C)C)c2)c1 +COc1ccccc1CC(=O)NC1c2ccccc2CNC1C +CC(=O)c1cccc(NCc2nnc(C(C)(C)C)o2)c1 +N#Cc1ccc(NC(=O)NCCNC(=O)C2CC2)cc1 +O=C(Cc1c2cccccc-2[nH]c1=O)Nc1cnc2ccccc2c1 +Cc1cc(=O)oc2c3c4c(cc12)CCCN4CCC3 +CC(O)CNC(=O)NCC(C(C)C)N1CCOCC1 +Cc1ccc(NC(=O)CC2CC(C)(C)OC2=O)cc1 +Cc1nn(Cc2cc(-c3ccccc3)on2)c(N)c1C#N +CCOC(=O)CCCSc1cc2c(cc1Cl)OCCO2 +Cc1ccc(C(=O)CNc2ccccc2Cl)cc1N +Cc1cc(F)ccc1NC(=O)Cc1ccc(O)cc1 +Cc1nccn1-c1ccc(NC(=O)Nc2ccccc2)cn1 +CCCc1cc(N2CCOC(Cn3cc(C)cn3)C2)n2ncnc2n1 +CCn1c(=O)n(CC(=O)N(CC2CCOC2)C2CC2)c2ccccc21 +CCOC(C)C(=O)NCC(=O)Nc1cccc(F)c1 +Cc1cc(OCC2CCCN(C(=O)OC(C)(C)C)C2)ncn1 +CCCCCNC(=O)c1ccc2c(c1)OCC(=O)N2 +NC(=O)NCCC(=O)N1CCCC1c1nnc2n1CCCCC2 +Cc1nc(C2CCCN(C(=O)c3cc(C)sc3C)C2)no1 +Cc1cccc(-c2noc(C(=O)NC3CCCC3)c2N)c1 +C#CCN(CC#C)C(=O)CCCc1cc(F)ccc1F +CCc1oc(C(=O)Nc2cccc(-n3cnnc3C)c2)cc1C +O=S1(=O)CCCN1CCCOc1ccccc1Cl +CC(=O)N1CCc2cc(NC(=O)NC(CO)c3ccccc3)ccc21 +O=C(Cc1ccccc1)NCCCNC(=O)c1cccnc1 +O=C(CC(F)(F)F)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +COc1ccc(C(C)C)cc1-c1cc(CO)nn1CC#N +Cc1ncc(C(C)NCC2COc3ccccc3O2)s1 +CCCOC1CCCN(C(=O)c2cc(C(C)C)no2)C1 +CN(C)c1ccc(-c2nn3cc(N)nc3s2)cc1 +CC(=O)c1ccc(C(=O)OCc2cc(=O)n3cc(C)ccc3n2)cc1 +CNC(=O)C1(C)CN(C(=O)c2ccn(C)n2)CCO1 +CC(NC(=O)Cn1cnc2c(cnn2C)c1=O)c1ccccn1 +O=C(CC1NC(=O)c2ccccc21)Nc1nc(C2CC2)n[nH]1 +COc1ccc(C2(c3nc(-c4cccnn4)no3)CCCC2)cc1 +CCCc1n[nH]c(C2CN(C(=O)c3c[nH]c(C(C)C)n3)CCO2)n1 +Cc1cc(C)n2cc(CNc3c(F)cccc3F)nc2n1 +N#Cc1ccc(Nc2ncc(Br)c(=O)[nH]2)cc1 +N#Cc1cccnc1NCc1nc2ccccc2s1 +Cc1ccc(S(=O)(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1 +Cc1ccc(C)c(S(=O)(=O)Nc2ccn(C)n2)c1 +CCNC(=O)CNS(=O)(=O)c1cc(N)ccc1CC +CC(C)Cn1ncc(C(=O)NCc2ncn(C)n2)c1C(F)F +COC(=O)c1sccc1CSc1ccccn1 +O=C(OCC1CCCO1)c1nn(-c2ccc(F)cc2)c2c1CCCC2 +COC1CCC2OCCN(CC(=O)Nc3ccc(F)cc3F)C2C1 +Cc1ccc(C(=O)CCC(=O)Nc2cccc(C#N)c2)s1 +Cc1c(C(=O)N2CCNC(=O)C2C(C)C)cnn1-c1ccncc1 +COCc1cc(C(=O)NC(C)(C)c2nc(C)c(C)s2)ccc1F +CC(OC(=O)c1ccc2c(c1)OCO2)C(=O)NC1CCCCC1 +CS(=O)(=O)NC1CCCN(C(=O)Cc2ccc(Cl)cc2)C1 +Cc1nc(CCNC(=O)COc2ccc(F)cc2)cs1 +CCOc1ccccc1NC(=O)c1cc(C)n(C2CC2)c1C +O=C(c1cccc(Cl)c1)N1CCC2C1CC(=O)N2c1cccnc1 +CN(C)c1ccc(NC(=O)c2ccc3c(c2)CCC3)cn1 +CCC(NC(=O)CCn1ccccc1=O)c1ccc(Cl)cc1 +O=C1COc2ccc(C(=O)N(Cc3ccccc3)C3CC3)cc2N1 +CCC(Sc1ncnc2c1cnn2-c1ccc(F)cc1)C(=O)OC +CC(C)OC(=O)CN1CCNc2cc(F)ccc21 +CC(C)c1cc(C2CCCN2C(=O)c2ccco2)no1 +C=CCNS(=O)(=O)c1nn(C)c2nc(C)c(Cl)c(C)c12 +COc1ccccc1C(=O)NCCC(=O)N1CC(C)CC(C)C1 +COc1cc(CNc2cc(C)on2)ccc1SC +Cc1cc(C)cc(CCNC(=O)CCc2cnn(C)c2)c1 +N#CCCCCOc1c(Cl)cc(Cl)cc1CO +Cc1cnc(C)c(Oc2cccc3c2NCCC3)n1 +COC(=O)C1CN(Cc2c(C)cc(Cl)cc2C)CCO1 +CCC(=O)N1CCCC(C(=O)Nc2ccc(C(C)=O)c(C)c2)C1 +CC(C)NC(=O)CSc1nccn1-c1ccc(C(C)C)cc1 +O=C(NCCNC(=O)c1cc2cccn2cn1)c1ccsc1 +CN(C(=O)c1c(F)cccc1Cl)C1(C#N)CCCCC1 +COCc1cccc(C(=O)Nc2cc(C)ccc2OC)c1 +CCOc1ccccc1-c1cn2cccc(CO)c2n1 +CC(=O)Nc1cccc(OCc2ccccc2C)c1 +O=c1cc(CNS(=O)(=O)c2c[nH]cn2)c2ccccc2[nH]1 +CCCNC(=O)NCc1ccccc1NS(=O)(=O)c1ccccc1 +COc1ccc(OCCC(=O)Nc2cn(C)c(=O)cc2C)cc1 +CC1CN(c2ccc(Br)cc2N)CCO1 +Cc1cccc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)n1 +Cc1cc(C(=O)Nc2ncc(Cc3ccc(C#N)cc3)s2)[nH]n1 +CNC(=O)NC(C)(C)C(=O)NCc1cccc(C#N)c1 +Cc1ccc2ncc(CN3CCC(Oc4ccc(F)cc4)CC3)n2c1 +CN(C)C(=O)N1CCN(C(=O)C2(C)CC2(Cl)Cl)CC1 +Cc1ccccc1-c1noc(CN(C)C(=O)c2cccs2)n1 +c1ccc2oc(C3CCN(c4ncnc5[nH]ncc45)CC3)nc2c1 +Cc1cc2c(cc1C)N(Cc1ccc(F)cc1)C(C1C=CC=NC1=O)N2 +CCOC(=O)N1CCN(C(=O)Nc2nc(C3CC3)cs2)CC1 +CC1Cc2ccccc2N1C(=O)NCC(=O)N(C)CC(F)(F)F +CCOC(=O)c1cnn2c1ncc1c(=O)n(-c3ccccc3C)ccc12 +O=S(=O)(c1ccc2cn[nH]c2c1)N1CCC(n2cccn2)CC1 +CCCCCNC(=O)Nc1ccc(C(=O)NC2CCOCC2)cc1 +N#Cc1ccc(C(=O)NCCOc2cccc3cccnc23)cc1 +Cc1c(C(=O)OC(C)C)sc2ncnc(N(C)CCO)c12 +COCCNc1ncnc2c1nnn2Cc1ccccc1 +Cn1ncc2c(=O)n(CC(=O)N3CCc4ccccc43)cnc21 +CN(C)C(=O)c1cc(NC(=O)c2ccc(-n3ccnn3)cc2)ccn1 +CC(OC(=O)c1cccn1C)C(=O)Nc1ccccc1C#N +COCC(=O)N1CCN(Cc2cc(=O)oc3c(C)c(O)ccc23)CC1 +CCc1sc(C(=O)OCCN2CCOC2=O)cc1C +COc1ccc(F)cc1-c1csc(NC(=O)c2oc(C)nc2C)n1 +CCOC(=O)c1ccc(NC(=O)c2cccn2C)c(O)c1 +CC(CNC(=O)c1cnccn1)N1CCOCC1 +COc1ccc(O)c(C(=O)Nc2cccc(C)n2)c1 +CSc1ccc(CNC(=O)C(NC(N)=O)C(C)C)cc1 +CC(=O)N1CCC(Nc2n[nH]c3nc(C)cc(C)c23)CC1 +O=C(Cc1cn2ccsc2n1)NCCNC(=O)c1ccccc1O +O=C1CCC(C(=O)NCCNc2cccc(Br)c2)N1 +Cc1ccccc1CC(=O)N1CCN(C2CC(C)OC2=O)CC1 +Cc1c(C(=O)NCCC(=O)Nc2ccccc2)cnn1-c1ccncc1 +CC(C)c1noc(CCCC(=O)N2CCCC(C(N)=O)C2)n1 +CC(=O)N1CC2CC(C1)c1ccc(NC(=O)c3ccco3)c(=O)n1C2 +O=C(Cc1csc(N2CCNC2=O)n1)Nc1c(F)cccc1F +O=C1COC2CN(Cc3ccccn3)CC2N1Cc1ccccn1 +CC(C)C(=O)Nc1ccc2c(c1)CN(C(=O)c1cccs1)CC2 +Cn1ccsc1=NC(=O)c1coc(-c2ccccc2)n1 +CCn1nc(CC(C)C)cc1C(=O)NC1(C(N)=O)CCCCCC1 +Cc1cccc(NC(=O)COC(=O)c2ccc(C#N)cc2)c1C +Cc1nc2ccccc2n1CC(=O)Nc1ccc(Br)cc1 +O=C(CCn1ccccc1=O)Nc1c2c(nn1-c1ccccc1)CCC2 +Cc1sc2ncnc(NCCNC(=O)c3cccnc3)c2c1C +CC(C)(CNC(=O)NC(C(N)=O)c1ccccc1)c1ccc(F)cc1 +CCN1C(=O)COc2cc(NCc3ccccc3F)ccc21 +O=C(Nc1nncs1)c1cc2ccccc2oc1=O +CC(Sc1nnc(N2CCOCC2)n1-c1ccccc1)C(N)=O +O=C(NCC(=O)N1CCC(Cc2ccc(F)cc2)CC1)c1ccoc1 +O=C(Nc1nccs1)c1ccc(-n2cncn2)cc1 +C=CCNC(=O)Nc1ccc(F)cc1Br +O=C(Nc1ccc(O)cc1)c1ccc2c(c1)CCO2 +Cc1ccc(N2CCCC(C(=O)c3nccn3C)C2)nn1 +CCC(C)Sc1nnc(-c2ccccc2OC)n1N +CCCCN(C)C(=O)NCCCN1CCOCC1 +CCOc1ccccc1CNC(=O)N(C)Cc1cc(C)on1 +CCC(NC(=O)c1sccc1C)(C(N)=O)C(C)C +CC=Cc1nnc(C(N)c2ccc(F)c(F)c2F)o1 +COc1ccc(OCc2nc(C#N)c(NCC3CCCO3)o2)cc1 +CC(C)(C)OC(=O)C1CCCN1Cc1cnc(-c2ccccn2)s1 +C#CCN(CC(=O)NCC(F)(F)F)C1CCc2ccccc21 +Cc1ccsc1C(=O)N1CCC2C1CCN2c1ncccn1 +Cc1ccccc1Nc1nccc(-c2cn(C)nc2C)n1 +CC1(C)CN(CC(=O)Nc2nccs2)CCO1 +Cc1nc(CNC(=O)NCCCOc2ccc(F)cc2)cs1 +CNC(=O)NCC1(c2ccccc2Br)CC1 +CCOc1ccc(CC2Oc3cc(N)ccc3N(C)C2=O)cc1 +CC(C)N1CC(C2NCCc3c(O)ccc(F)c32)CC1=O +CCn1c(SCc2ccccn2)nnc1-c1cn(C)nc1OC +CC(C)CC(=O)N(C)Cc1csc(C#CCCO)c1 +CC(=O)N1CCCC1C1NCCc2c1ccc(Cl)c2F +CS(=O)(=O)c1cnc(N2CCCC(O)C2)nc1N +CCc1nnc(NC(=O)CSc2ncccn2)s1 +CC1(C)CNc2cc(F)c(F)cc2N1Cc1ccncc1 +Cc1nc2nc(C)c3c(=O)n(-c4ccn[nH]4)ccc3n2n1 +Cc1cc(=O)[nH]c(-c2cccc(NC(=O)CC(C)C)c2)n1 +CCc1ccc(S(=O)(=O)N2CC=C(C)C2C(=O)OC)cc1 +COc1ccccc1OCC(=O)NCC1(O)CCc2ccccc2C1 +Clc1cccc2c1CCN(Cc1nc(-c3cnccn3)no1)C2 +O=C(Cc1csc(-c2ccc(F)cc2)n1)NCc1ccco1 +O=C(CNC(=O)NCC(c1ccccc1)N1CCOCC1)NC1CC1 +CC(C)OC(=O)C1CCCN1Cc1cc(C#N)cs1 +COc1c(C)cc(Cl)cc1CCCCn1cc(N)cn1 +N#CC1Sc2ccccc2N1C(=O)OCc1ccccc1 +C=CCC(CC=C)C(=O)Nc1cccc(Cl)c1C(N)=O +CC(C)Cc1nc(-c2ccc3nc[nH]c3c2)n(-c2ccccn2)n1 +Cc1nn(C)c(=O)c(C(=O)N2CCC(OC3CCCCC3)CC2)c1C +CC(C)CCNC(=O)c1nnc(C(=O)Nc2ccc(F)cc2)s1 +COc1ccccc1CC(=O)N1CCN(c2nccs2)CC1 +N#Cc1ccc(OCCSc2nccn2Cc2ccccn2)cc1 +COc1ccccc1C(=O)NCC(=O)NCc1ccc[nH]1 +COc1cccc(-c2nnc(SCC(=O)c3ccc[nH]3)n2C)c1 +O=C(OCc1ccccc1)C1CCCN1C(=O)c1ccc(F)nc1 +CCCn1nnnc1Cn1cnc2cc(C)c(C)cc21 +O=C(Cc1c(Cl)cccc1Cl)NC1CCCCC1O +COC1CCC(CC(=O)Nc2nccn(C)c2=O)CC1 +CCc1noc(CC)c1CC(=O)Nc1cc(C)cnc1OC +CC(C)CN(C)C(=O)C(NC(=O)c1ccc(F)cc1)C(C)C +CCOC(=O)Cn1c2ccc(F)cc2c2nc(C)sc21 +Cn1c(C(=O)NCCc2ccc(Cl)cc2)cc2occc21 +Cc1cc(C(=O)N2CCCN(C)c3ccc(Cl)cc32)no1 +COCCOC(=O)c1cc(-c2ccc(OC)cc2)c(C)s1 +O=C(COc1ccc(F)cc1Br)NCc1cccnc1 +CSc1ncccc1C(=O)Oc1ccc(C(C)=O)cc1 +CC(C)CC(=O)N1CCCN(c2nnc3ccccn23)CC1 +CS(=O)(=O)NC(c1ccc2c(c1)CCC2)c1cccs1 +CCSc1nnc(C2(C)COc3ccccc3O2)n1CC +COc1ccc(S(=O)(=O)N(C)Cc2ccc(Cl)cn2)cc1 +CCN(Cc1ccco1)C(=O)c1ccc2c(c1)CCC(=O)N2 +Cc1cccc(NC(=O)NC2CCCN(c3ccccc3F)C2=O)c1 +CC(=O)c1ccc(NC(=O)C2CCCc3ccccc32)cc1 +CCCc1cc(=O)n2nc(C)c(-c3ccc(OC)c(OC)c3)c2[nH]1 +O=C(Cc1ccon1)N1CCOc2ccc(C(F)(F)F)cc21 +CS(=O)(=O)N1CCN(C(=O)c2cccc(-n3cccc3)c2)CC1 +COc1cc(C(C)NC(=O)NCc2cc(C)on2)ccc1F +CC(C)NC(=O)C1CCN(C(=O)Cc2c(F)cccc2F)CC1 +CN(C)C(=O)CSc1nnc(-c2ccco2)n1C +CCOC(=O)C1=C(COC(=O)c2cccc(F)c2)NC(=O)NC1 +COc1ccccc1CN(c1nc(C)nc2oc(C)nc12)C1CC1 +CCn1cc(CNC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cn1 +CC1=CC(C)=NC(=O)C1CNC(=O)CCc1ccco1 +Cc1nccc(-c2cccc(NCC(=O)N3CCNC(=O)C3)c2)n1 +Cc1c(C(=O)NC2CCCC2Cc2ccccc2)cnn1C +CCOCCCn1c(C(C)=O)nc2ccc(Cl)cc21 +CC(=O)c1cc(F)ccc1N(C)Cc1cscn1 +COc1ccc(SCC(=O)N(C)Cc2cccs2)cc1 +CC1CCC(NC(=O)NCCC(=O)NC2CCCCC2)CC1 +Cc1cc(C)c(C)c(OC(=O)Cc2cc3ccccc3[nH]c2=O)c1 +COc1ccccc1CN(C(=O)C1CCOc2ccccc21)C1CC1 +Cc1c(C(=O)Nc2ccccc2F)cnn1-c1ccccn1 +C=C1C(C(=O)Nc2ccc(F)cc2)C1C(=O)Nc1ccc(F)cc1 +C=CCN(CC=C)S(=O)(=O)c1ccc(C(C)=O)cc1 +CCOCCCNC(=O)Nc1ccc(Br)cc1C +COc1ccc(C(=O)Nc2nncs2)cc1OCc1ccncc1 +Cc1cc(C)c(C(=O)NC(C)c2c(C)noc2C)c(C)c1 +CN(C)C=Cc1nnnn1-c1ccc(Cl)c(Cl)c1 +CCc1ccccc1NC(=O)C1Nc2cc(F)ccc2S(=O)(=O)N1 +CC(=O)NCC(=O)NCC(=O)N(C)C1CCC(C)CC1 +O=S(=O)(NC1CC1)c1ccccc1NCC1CCCOC1 +O=C(c1c[nH]c(=O)cn1)N1CCC(c2ccc3c(c2)OCO3)C(O)C1 +CS(=O)c1nncn1CCCc1nc2ccccc2o1 +O=c1c2nnc3ncnn3c2ccn1-c1ccc(OC(F)(F)F)cc1 +Cc1ccc(C(C)Nc2ccc(Cl)c(C(N)=O)c2)s1 +COC(=O)CNC(=O)c1ccccc1-c1ccccc1C#N +C=CCNC(=O)CCCOc1ccc(Cl)cc1 +CCC(NCc1cccnc1)C(=O)c1ccc2c(c1)NCCO2 +CCC1CCCN(C(=O)c2sc3ncn(C)c(=O)c3c2C)C1 +CCOC(=O)c1cccc(Cn2nnc3ccccc32)c1 +CNS(=O)(=O)c1ccc(CNC(=O)NC(C)C2CCCO2)s1 +CCC(C)Cn1c(CNC(=O)C(C)C)nc2ccccc21 +CC(c1ccccc1F)N(C)C(=O)c1ccc2c(c1)OCO2 +Cn1nc(-c2ccccc2)cc1C(=O)Nc1ccc(C(N)=O)cc1 +NS(=O)(=O)c1ccc(Sc2cccs2)s1 +CCOc1ccccc1-c1nc2sc(COC)nn2c1CO +Cc1cccc(NCCC(O)c2ccc(F)cc2)c1 +Cc1ccc(-c2cc(C(=O)N3CCCC3C(N)=O)on2)cc1 +Cc1nonc1C(=O)Nc1cnn(Cc2ccc(Cl)cc2)c1 +CCOC(=O)c1csc(NC(=O)c2ccccc2C)n1 +Cc1ccc(C(=O)NC(C)COCC(F)(F)F)c(=O)[nH]1 +CC(C)c1nnc(NC(=O)C2CC(=O)N(c3ccccc3)C2)s1 +O=C(Nc1ccccc1)Nc1cccc2[nH]ccc12 +Cc1nc(-c2cccc(CNC(=O)c3ccc(=O)n(C)c3)c2)n[nH]1 +Cc1ccn(Cc2cn3cc(Br)ccc3n2)c(=O)c1 +COc1ccc(-c2nc(COC(=O)c3ccncc3F)no2)cc1 +CCC(C)NC(=O)C1(C)CCC(=O)N1CCc1ccc(C)cc1 +COc1ccccc1NC1C(=O)Nc2ccc(F)cc21 +CCN(Cc1nonc1C)C(=O)c1nn2cccnc2c1Cl +Cc1nn(C)c(C)c1CCNC(=O)N1CCCN(C(=O)C2CC2)CC1 +CCc1nn2c(-c3ccc(C(F)(F)F)cc3)nnc2s1 +Cc1nc2c(NCCN3CCOCC3)ncnc2[nH]1 +COc1ccc(OC(C)C)c(NCc2noc(C)n2)c1 +CN(C(=O)c1csnn1)C1CCN(c2ccc(Cl)cc2)CC1 +Cn1ccnc1C(NC(=O)Nc1ccccc1)c1ccccc1F +COc1ccsc1S(=O)(=O)NCc1ccc(C)c(F)c1 +Cc1c(C(C)NC(=O)c2cnns2)oc2ccccc12 +CCN1C(=O)NC(c2ccccc2OC)C(C(=O)OC)=C1C +COc1ccc(-c2nc3c(C)cccn3c2C#N)cc1 +CCc1nnc(NC(=O)NCc2ccccc2OC(F)(F)F)s1 +CCC(NC(=O)c1ccc2cc[nH]c2c1)c1nccs1 +CN(C)C(=O)CSc1nnc(-c2ccccc2F)n1C +Cc1cnc(CCNC(=O)NCCc2ccccc2)s1 +Cc1nc(N2CCOCC2)[nH]c(=O)c1Cc1ccccc1 +CC(=O)Nc1ccc(-c2nc3cc(Cl)c(NC(C)=O)cc3[nH]2)cc1 +CN(C(=O)COc1ccc(Cl)cc1N)C1CC1 +CCCn1c(NC(=O)c2cnn3c(C)cc(C)nc23)nc2ccccc21 +Nc1c[nH]c2cc(-c3ccccc3Cl)nn2c1=O +O=C(Nc1ccc2c(c1)C(=O)NCC2)c1cc(Cl)c2c(c1)OCO2 +Cc1ccc(Cl)cc1N(CC(N)=O)S(C)(=O)=O +C=CCn1c(SC(C)C(=O)CC)nnc1-c1ccncc1 +CC(C)(C)NC(=O)COC(=O)COc1ccccc1Cl +COC(=O)c1cc(-c2ccc3c(c2)CC(=O)N3)nn1-c1ccccn1 +O=C(c1cc(C2CC2)[nH]n1)N1CCN(C(=O)C2CCCC2)CC1 +O=c1ccc(=O)n2n1CN(c1ccc(Br)cc1)C2 +O=c1c2nnc3ncnn3c2ccn1-c1cccc(C(F)(F)F)c1 +CSc1ccc2nc(NC(=O)c3cc(C)nn3C(C)C)sc2c1 +CC(C)(CCC#N)CN1CCOC(c2cccc(O)c2)C1 +COc1ccc(CN(C)c2nc3c(cnn3C)c(=O)[nH]2)c(OC)c1 +O=C(c1ccc[nH]c1=O)N1CCCC1c1ccc(F)cc1 +Cc1cccn2cc(CSc3nnc(-c4ccncc4)o3)nc12 +CCOc1ccc(S(=O)(=O)N2CC(C)OC(C)C2)c2ccccc12 +CC(NC(=O)C(C)(C)C)C(=O)Nc1cccc(C(=O)NC2CC2)c1 +NC(=O)NCCc1ccc(C(=O)OCc2ccc3nn[nH]c3c2)cc1 +Cn1cc(CCC(=O)C(C#N)c2ccc(C(F)(F)F)cn2)cn1 +Nc1cccc(-c2nccn2Cc2ccccn2)c1 +O=C1CCCN1c1ccccc1NCc1cnn(-c2ccccc2)c1 +CC(OCC(F)(F)F)C(=O)Nc1cccc(-c2cn[nH]c2)c1 +CCOc1ccccc1-n1ccn(Cc2ccccc2F)c(=O)c1=O +CC1CN(C(=O)CCc2ccccc2O)CC(C)O1 +CCC1C(=O)NCCN1C(=O)C(C)Oc1cccc(C(C)=O)c1 +CN(Cc1ccc(Br)cc1)C(=O)CCC#N +O=C1CCCN1c1ccc(NCc2ccc(-n3cncn3)cc2)cc1 +N#Cc1ccc(NCC(=O)N2CCCc3ccccc32)cc1 +CC(C)CCC(C)NC(=O)NC1CCN(C(=O)c2ccoc2)CC1 +O=C(CN1CCN(C(=O)c2ccccn2)CC1)Nc1cccc(F)c1 +Cc1ccc2c(c1)-c1c(cnn1CC(=O)N(C)c1ccccc1)CO2 +COc1ccc(C(=O)OCc2csc(NC(C)=O)n2)cc1OC +CCN(CC)C(=O)c1cc(C(=O)Nc2ccc(F)cc2F)n(C)n1 +O=C(NCc1ccc(Cn2cccn2)cc1)c1ccc(F)cc1Cl +COc1ccc(C(=O)Nc2ccc(OC(F)F)cc2)cc1OC 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+NC(=O)Cn1ccnc1-c1cccc(Cl)c1Cl +COc1ccc(OC)c(C(O)CNC(=O)Nc2nccs2)c1 +COCc1cccc(NC(=O)N2CCc3cc(F)ccc3C2)c1 +CCCN1Cc2ccc(Cl)c(N)c2CS1(=O)=O +O=C(CN(CCO)c1ccccc1)NCc1ccc2c(c1)OCO2 +CS(=O)(=O)NC1CCN(C(=O)NCCNc2cnccn2)CC1 +CC1COCC(C)N1CC(=O)Nc1nc2ccc(F)cc2s1 +CC(=O)c1ccc(NC(=O)c2cncc(N)c2C)cc1 +CCn1nc(C(C)(C)C)cc(C(N)c2cccs2)c1=O +C=C(C)COCCNS(=O)(=O)c1ccc(C#N)cc1Cl +CCCS(=O)(=O)N1CC=C(c2cn(CC)c3ncccc23)CC1 +CC(=O)Nc1ccc(-c2csc(N(C)c3ccc(O)cc3)n2)cc1 +Cc1cc(Cl)ccc1NC(=O)COc1cccc(N)c1 +Cn1c(CNC(=O)c2ccc(C3CCCCC3)cc2)nnc1C1CC1 +O=C(c1coc(CN2CCOCC2)c1)N1CC(c2ccccn2)C1 +Cc1cc(=O)oc2cc(O)c(NS(C)(=O)=O)cc12 +CC(C)NC(=O)c1cn2c3c(cccc3c1=O)CC2 +O=C(NCCCOc1cccc2cccnc12)c1ccc(=O)oc1 +Cc1c(Cl)cccc1S(=O)(=O)N1CCN(C(=O)N(C)C)CC1 +CNC(=O)COC(=O)C1(c2ccc(Cl)cc2Cl)CCOCC1 +COC(=O)CC(C)NC(=O)c1cccn1Cc1cccs1 +O=C(Nc1ccc(F)cc1)c1ccc(CN2CCOCC2)cc1 +CCN(Cc1ccccc1NC(=O)NCc1cccc(C)c1)C(C)=O +CCC(C)(C)C1CCCN1C(=O)c1ccc(OCC(F)F)nc1 +CS(=O)(=O)NCC(=O)NC1(c2ccc(Br)cc2)CC1 +CC(C)NC(=O)CN1CCN(C(=O)Cc2cccc(F)c2F)CC1 +COc1cccc(-c2ccnc(N3CCOCC3)n2)c1 +CN(C)C(=O)N1CC2CCC(C1)N(S(=O)(=O)c1cccnc1)C2 +CN(C)S(=O)(=O)c1cccc(COC(=O)CC(C)(C)C)c1 +CSc1cccc(N(C)C(=O)c2cccc3ccc(C)nc23)c1 +Cc1oc(-c2ccsc2)nc1CC(=O)Nc1sccc1C#N +N#Cc1cc(Br)ccc1NCCC(=O)N1CCOCC1 +COCc1ncc(C(=O)NCc2ccccc2)c(N)n1 +NC(=O)N1CCCN(C(=O)c2c[nH]nc2-c2cccc(Cl)c2)CC1 +Cc1cc(CNC(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)ccc1F +COc1ccc(-c2nc(CSc3nnc(N)n3C3CC3)no2)cc1 +CCOc1cc(C(=O)Nc2cc(C)on2)ccc1OC +Cn1cc(NS(=O)(=O)c2ccc(OCC(F)F)cc2)cn1 +FC(F)(F)c1cccc2c1C(c1ccncc1)NCC2 +N#Cc1ccc(OCCCOCC(F)(F)F)cc1 +Cc1cc(C(=O)Nc2ccccc2OC(F)F)c(C)s1 +O=C(Nc1cc2ccccc2oc1=O)c1cnn2c1OCCC2 +Cn1cnc(CNC(=O)NCCOc2ccc(C#N)cc2)n1 +Cc1nnc(CNc2cccc(Cl)c2F)n1C +Cc1ccc2cccc(Nc3ncnc(N4CCCCC4C)c3N)c2n1 +O=C(c1ccn(-c2ccccc2)n1)N1CCc2cc(F)ccc2C1 +Cc1cccc(CNC(=O)COc2ccc(-c3nnco3)cc2)c1 +CC(C(=O)N(C)Cc1ccc(OC(F)(F)F)cc1)n1cncn1 +Cc1ccn2c(=NC(=O)c3cccc(Oc4cnccn4)c3)[nH]nc2c1 +CC(C)N(C)S(=O)(=O)c1ccc2c(c1)CCC2 +Cc1ccc(-c2nnn(CC(=O)Nc3cc(C)ccn3)n2)cc1 +Cc1nc(NCCN2CCOCC2)c(N)c(OCC(C)C)n1 +Cc1noc(OCC(=O)NC(C)CCC(C)C)n1 +CN(C)c1nc(-c2ccncc2)nc(-c2ccc(Cl)cc2)c1C#N +CC1Oc2c(Br)cc(Cl)cc2N(C)C1=O +CC(C)(C)N1CC(C(=O)N(Cc2cocn2)Cc2cocn2)CC1=O +CC(C)(C)c1ccc(OCC(=O)NCC(N)=O)c(C(C)(C)C)c1 +CCc1nc(CC(=O)Nc2ccc(OC)c(OC(F)F)c2)cs1 +CC(O)CNC(=O)c1ccccc1CSc1nc2ccccc2o1 +CCCCN(C)C(=O)CN1C(=O)C(C)Oc2cccc(N)c21 +Cc1ncncc1C(=O)N1CCCCC1Cn1cccn1 +COC(=O)C1=C(C(C)C)N(C(C)C)C(=O)NC1c1ccccn1 +Nc1cccc(NC(=O)CCOCC2CCCO2)c1 +Cc1ccc(C(=O)OCc2nnc(-c3ccccc3)o2)o1 +CCc1ccc(-c2ccc(C(=O)NC(C)CO)o2)cc1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1cccc(C)c1C(N)=O +CCCOCC(=O)Nc1cccc(N(C)C(C)C)c1 +COC(=O)c1cccc(NC(=O)c2cnc3ccc(C)cn23)c1 +COc1cccc(CCC(=O)N2CCN(CC(C)(C)O)CC2)c1 +CCC(CC)NC(=O)c1ccccc1C#CCCO +CC(C)Cc1ccc(S(=O)(=O)Oc2cccc(CC(N)=O)c2)cc1 +C=CCNC(=O)C(C)Nc1cccc(Cn2cccn2)c1 +CCCc1ncc(CN2CCOC(Cc3ccc(OC)cc3)C2)cn1 +COc1cccc(C2(NC(=O)c3c(C)noc3C)CCCC2)c1 +Cc1nnc(Cc2ccc(NC(=O)COc3ccccc3)cc2)o1 +Cc1cc(C(=O)Nc2ccnn2-c2ccccc2C)[nH]n1 +C#CCOC(=O)c1cccc(S(=O)(=O)N2CC(C)CC(C)C2)c1 +CC(C)(C)CC(=O)Nc1ccc(Oc2cccc(C(N)=O)c2)nc1 +CCSc1cc(C(=O)Nc2ccc3c(c2)OCCCO3)ccn1 +Cc1ccc(Cn2cc(NC(=O)c3cccnc3)cn2)cc1 +CC(C(=O)Nc1ccc(F)cc1F)S(=O)(=O)c1ccc(O)cc1 +CCN1CCN(Cc2snnc2C)C(=O)C1=O +O=C(Nc1ccccc1N1CCOCC1)c1ccc(-c2cnco2)cc1 +C=CCOC(C)C(=O)NCc1cccc(NC(C)=O)c1 +Cc1[nH]ncc1CCCNC(=O)c1cc(C(C)C)[nH]n1 +Cc1noc(C)c1CCNC(=O)NCC(C)(C)c1ccncc1 +CC(OC1CCCCCC1)C(=O)NCc1nc[nH]n1 +NS(=O)(=O)Cc1ccc(NC(=O)c2ccccn2)cc1 +CC1CCN(C(=O)CN(Cc2ccc(F)cc2)S(C)(=O)=O)CC1 +CC(CC1CCCC1)C(=O)N1CCCC1C(=O)NCc1ccco1 +CNS(=O)(=O)c1ccc(F)c(C(=O)N(C)CC(C)C)c1 +CC(C)c1ocnc1C(=O)Nc1ccc2c(c1)CCO2 +Cc1ccc(Br)cc1-c1nn(C)c(C)c1N +Cc1noc(C)c1CCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +CC(CCCO)NC(=O)N1CCN(c2ncnc3sccc23)CC1 +NC(=O)C1CCN(C(=O)Nc2nnc(-c3ccccc3)s2)CC1 +CC1Oc2ccccc2N(CCC(=O)OCCc2cccs2)C1=O +COc1ccc(CCC(=O)Nc2ccccc2N2CCCC2=O)cc1 +CCSc1ccc(Cl)cc1NC(=O)c1ccc(OC)nn1 +CCOC(=O)C1CCCCC1N1CCN(C(=O)C2CC2C)CC1 +O=C(c1ccnc2ccccc12)N(CC(F)F)C1CC1 +O=C(NCc1cccnc1Oc1ccc(F)cc1F)c1ccc[nH]1 +CCC1(CC)Cc2ccccc2-c2nc(CN3CCCC3)[nH]c(=O)c21 +CC(CCCO)NC(=O)NCCc1cccc(F)c1 +CCn1ccc(=O)nc1SCc1ccccc1C(C)(C)C#N +C#CCNC(=O)c1ccccc1NCC(=O)Nc1cc(C)on1 +NC(=O)c1ccncc1NC(=O)c1ccc(Cl)cn1 +CCC(CO)Nc1nc(C)c2c(c1C#N)CCCC2 +CC(C)c1[nH]nc(C(=O)N(C)CC2CCCO2)c1N +COc1cccc(OCc2nc(C(=O)N3CCCC3)cs2)c1 +COc1ccc(C)cc1NC(=O)COc1ncnc2sccc12 +Cc1ccc(C)c(NC(=O)c2ccc(C)nc2N)c1 +Cc1nc(Cn2cc(C(F)(F)F)ccc2=O)n(CC(F)(F)F)n1 +CCC(C)C(=O)NCC(=O)Nc1cc(C#N)ccc1C +COc1cc(OC)cc(C(=O)NC(C(=O)N(C)C)C(C)C)c1 +Cc1cc(=O)c(C(=O)NC(C)C(C)Oc2ccccc2)c[nH]1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCN(C(C)C)CC2)c1 +Cc1cc(CN(C)C(=O)C2CC(=O)N(Cc3ccccn3)C2)no1 +Fc1ccc(Cn2ncc3c2CN(c2nccc4occc24)C3)cc1 +CNS(=O)(=O)Cc1ccccc1CNc1ncnc2sccc12 +Cc1nc(-c2cccnc2)ncc1C(=O)N1CCC(C)(O)C(C)(C)C1 +COc1c(F)ccc2c1CCNC2c1c(C)ncnc1C +N#Cc1cccnc1NCCNC(=O)c1ccc(=O)[nH]c1 +O=C(CCC(=O)c1ccccc1)Nc1ccn(Cc2ccncc2)n1 +CNc1nc(-c2sc(C)nc2C(C)C)cs1 +O=C1c2ccccc2NC(c2ccccc2OC(F)(F)F)N1C1CC1 +CC(Sc1ccc(O)cc1)C(=O)NC1CCCCC1 +Nc1c[nH]nc1C(=O)NC1CCc2ccccc2C1 +Cc1nc2ccc(NC(=O)N3CCCCCC3)cc2s1 +Cc1nnc2ccc(NCC(C)c3nc4ccccc4o3)nn12 +CCS(=O)(=O)NCc1cccnc1OCc1ccccc1 +COCc1ccc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1 +O=C(NCc1cccnc1)c1cc(F)ccc1-n1cnnn1 +Cc1ncsc1CNC(=O)NC(c1nnc2ccccn12)C(C)C +CCOC(=O)Nc1sc(C)c(C)c1C(=O)OC +CC(C)(C)OC(=O)C(N)c1cccc(Br)c1 +COC(=O)c1cc(Br)cc(NC(C)=O)c1 +CC(=O)c1ccc(NC(=O)CCc2nc(-c3ccco3)no2)cc1C +CCCCN1CCN(C(=O)c2cc3cn(C4CC4)cc3s2)CC1 +Cc1cc(C(=O)Nc2ccc3c(c2)OCO3)n(C)n1 +CCNC(C#N)c1cc(OC)c(OC)cc1OC +Cc1oc2ncnc(NCc3ccnc(-n4ccnc4)c3)c2c1C +COc1ccc(CC(=O)Nc2nnc(-c3ccno3)o2)cc1C +CC(=O)N1CCc2c(nc(-c3ccccn3)nc2NC(C)C(C)C)C1 +CCOc1ncccc1CNC(=O)c1cnccn1 +CC(NC(=O)Nc1cccc(N2CCOC2=O)c1)C(=O)OC(C)(C)C +N#Cc1ccccc1NC(=O)CCCc1cccs1 +CCOc1c(Cl)cccc1NC(=O)NC(C)c1cn(C)nc1C +CN(CCOc1ccccc1)S(=O)(=O)c1ccc(F)cc1 +CCC(CC)NC(=O)Nc1ccccc1S(C)(=O)=O +CC(CC#N)N(C)C(=O)Cc1cccc(Br)c1 +COc1ccc(NC(C)=O)c(NC(=O)C2CCC2)c1 +Cc1nc(C)c(C(=O)OC(C)C(=O)Nc2ccccc2)s1 +COc1ccc(-c2cc(=O)n(CC(=O)N3CCC(C)CC3)cn2)cc1 +O=S(=O)(Cc1nnc(-c2ccccc2)o1)c1ccccc1 +Cc1cc(CNC(=O)c2cc(Br)ccc2Cl)nn1C +COC(=O)C1CCCN(Cc2cnc(C(C)(C)C)s2)C1 +COc1cc2c(cc1OC)CN(C(=O)c1ccc(F)cc1F)CC2 +C#CCN(Cc1cc(C(=O)OC)c(C)o1)C1CCc2ccccc21 +CCc1noc(CSc2nc3ccccc3[nH]2)n1 +Cc1cccc(NC(=O)CNC(=O)N2CC(=O)Nc3ccccc32)c1 +COc1ccc(-c2ccc(CO)o2)c(Br)c1 +O=C(c1ccc(=O)[nH]c1)N1CCN(CC(O)Cc2ccccc2)CC1 +CCc1n[nH]c(=O)c(CNC(=O)c2ccccc2F)c1CC +Cc1ncccc1CN(Cc1cccnc1)CC1CCCO1 +Cn1nc(CCC(=O)Nc2nc3ccc(Cl)cc3s2)ccc1=O +Cc1cc(C(=O)Nc2ccc(CS(N)(=O)=O)cc2)c(C)n1C(C)C +Cc1ccc(NC(=O)c2ccc(N3CCOC3=O)cc2)c(C)c1 +CC(C)(C)OC(=O)N1CCCc2cc(NC(=O)c3cnc[nH]3)ccc21 +O=C(CNc1ccc(F)c(F)c1)Nc1ccccc1F +CC(C)c1nn(C(C)(C)C)c2c1C(CC#N)CCC2 +Cc1c(Cl)cccc1NC(=O)Cc1nnc(-c2ccsc2)o1 +O=S(=O)(c1ccc(NC2CCCC2)nn1)C1CCCCC1 +O=C(c1cc(F)c(Cl)cc1Cl)N1CCOCC1C1CC1 +CCOC(=O)c1cnc2nc(COC)nn2c1C=CN(C)C +CNC(=O)c1cc(NC(=O)C(C)C)n(-c2ccccc2)n1 +Cc1cc2nn(-c3ccc(Cl)cc3)nc2cc1N +O=C(CNC(=O)c1ccc(F)cc1)NCCc1ccccc1 +N#CCn1c(=O)n(CC2CCCO2)c(=O)c2ccccc21 +Nc1cc(Br)c2nnc(-c3cccs3)n2c1 +C=CCNC(=O)CSc1nc2ccccc2n1C(F)F +CCOC(=O)c1[nH]c2cc(Br)ccc2c1N +CCc1ccc(NCC(O)c2cccc(N)c2)cc1 +CC(C)n1cnc(S(=O)(=O)N2CCc3cccc(F)c32)c1 +Cc1ccc(OC2CCN(S(=O)(=O)C3CCCCC3)CC2)cn1 +O=C(Nc1ccccc1Cl)c1ccc(NC2CC2)nc1 +CCCN(CC(F)(F)F)C(=O)c1cccc(NC)n1 +CCOc1ncccc1CNC(=O)c1c(C)nn(C)c1C +CC1CCCC(CNC(=O)C(C)OCC(F)(F)F)C1 +CCOc1ccc(CC(=O)Nc2ccc(-n3ccnc3C)nc2)cc1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)C(C)(C)n1cc(Cl)cn1 +Cc1ccc(=O)n(CC(=O)NCc2cccnc2)n1 +CC(=O)Nc1cccc(NCc2ccccc2)c1C +CC(C)(C)c1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1 +O=C(NCc1ccnc(OC2CCC2)c1)C1CCCCC1 +O=C(NCC1CC1)C1CCCN(C(=O)Cn2cnnn2)C1 +O=C(COc1ccc(F)cc1Cl)NCC1CCOC1 +CC(NC(N)=O)C(=O)Nc1cc(Cl)ccc1N(C)C +NC(=O)c1c(NC(=O)c2csnn2)sc2c1CCCC2 +Cc1nc(C2CC2)nc2sc(C(=O)NC(C)C3CCCO3)c(C)c12 +Cn1c(SCc2nccn2C(F)F)nnc1-c1ccc(F)cc1 +CCc1noc(CN(C)C(=O)c2ccnc(OC3CCC3)c2)n1 +Cc1cc(C(=O)NCC(C)(C)c2ccncc2)sc1C +CCc1cnccc1C(=O)N1CCC(Nc2cccnc2)CC1 +COC(=O)C1CCN(C(=O)Cn2cnc3cc(C)c(C)cc32)CC1 +COc1cc(S(C)(=O)=O)c(OC)c2c1CC(C)NC2 +CC(NC(=O)N1CCC(CSc2ccccc2)C1)c1nncn1C +CC(C)CNC(=O)CN1CCN(c2ccc(F)cc2)CC1 +COc1ccc(C(C)NCC(=O)NC(C)C)cc1 +CCC(C)NC(=O)N(C)Cc1ccc2c(c1)OCO2 +CCOc1ccc(-c2cc(C#N)nn2CC)cc1OCC +N#CCc1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +N#CCCN(CCC#N)Cc1ccc(Cl)c(F)c1 +CC(C)C(=O)N1CCC(NC(=O)c2ccsc2)CC1 +CNC(=O)NC(C)(C)C(=O)Nc1ccc(F)cc1C +O=c1c2ccc(Cl)c(Cl)c2ccn1CCO +CCc1noc(CC)c1CNC(=O)c1cc(OC)c(C)c(OC)c1 +COc1cccc(NC(=O)c2ccc(NC(=O)C(C)C)cc2)c1 +CC(=O)Nc1cc(C(=O)OCC(=O)c2ccc(F)cc2)ccc1C +CCC(=O)Nc1cccc(C(=O)NCc2ncc(-c3ccccc3)[nH]2)c1 +CCCn1nc(-c2ccc(F)cc2F)cc(C#N)c1=O +O=C1NCCCC1NCc1ccc2c(c1)OCCO2 +Cc1ccccc1C(=O)NC(CO)Cc1ccccc1 +O=c1cc(C2NCCc3cc4c(cc32)OCC4)cc[nH]1 +CCn1cc(C#N)c(=O)n(CC(=O)c2ccc(C)cc2)c1=O +O=C(NCCCCN1CCOCC1)c1ccc2ccccc2n1 +C=CCSc1nnc(NC(=O)CSc2ccccc2)s1 +Cc1cc(C(=O)NC2CCc3c(Cl)cccc32)[nH]n1 +COc1ccc(O)c(C(=O)NCC(CC(C)C)N2CCOCC2)c1 +Cc1cncc(C2NCCc3ccc4c(c32)CCO4)c1 +C#CCOc1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1 +O=C(CCn1cncn1)Nc1n[nH]c2ccccc12 +CNC(=O)Cn1cc(NCc2ccc(Br)cc2)cn1 +CC(=O)Nc1ccc(NC(=O)c2ccccc2Br)cc1 +CCn1c(CNC(=O)Cc2cn3cccc(C)c3n2)nc2ccccc21 +O=C(NCC1CCCO1)Nc1cnn(Cc2ccccc2)c1 +C#CCCN1CCN(C(=O)c2ccc(OC)c(OC)c2OC)CC1 +O=C(Nc1nnc(-c2ccccn2)s1)C1CCCC1 +O=C1Nc2ccc(F)cc2C1NCc1ccccn1 +O=c1n(-c2cccc(Cl)c2)c(=O)n2n1CC=CC2 +CC(C)Nc1ncnc2ccc(Br)cc12 +COCC(C)N1CCN(c2nc(N)c3ccccc3n2)CC1 +Cc1ccc(CN(C(=O)CNc2ccccc2)C2CC2)cc1 +CC(C)(C)c1noc(CCC(=O)Oc2ccc3c(c2)CCC(=O)N3)n1 +CC(C(=O)NC1CCCCC1)N1CCn2c(nn(C)c2=O)C1 +C#CCNC(=O)NCC1(N2CCOCC2)CCCCC1 +CC(c1nnc(-c2cccs2)o1)n1nc(-c2cccs2)oc1=O +CCOc1nnc(CN2CCN(C(=O)c3ccco3)CC2)s1 +CCCn1c(C)c(C(=O)N2CC(C)OC(C)C2)c2cc(OC)ccc21 +O=C(Nc1ccccc1-n1cncn1)c1ccc(F)cc1 +COc1ncccc1C(=O)NCC#Cc1ccccc1N(C)C +C#Cc1cccc(NC(=O)N(C)C(C)c2ccccc2OC)c1 +CC(C)NC(=O)CCNC(=O)c1cc(Br)c[nH]1 +Cc1cc(C)n(Cc2ccc(C(=O)NCCc3ccccn3)cc2)n1 +CC(C)(CO)Nc1ccc(NC(=O)c2ccccc2F)cn1 +C=C1C(C2COC(C)(C)O2)OC2OC(C)(C)OC12 +Nc1nc(N)nc(CN2CC=C(c3ccccc3Cl)CC2)n1 +CCCc1ccc(C(=O)NCC(O)c2ccc(C)o2)cc1 +CCC(NC(=O)c1sccc1C)c1ccc(C)cc1 +C=CCn1c(C)nnc1SCC(=O)N(CC)C1CCCCC1 +CC(C(=O)Nc1ccn(C)n1)c1ccc(CC2CCCC2=O)cc1 +Cc1c(C(=O)OCc2ccccn2)oc2c1C(=O)CC(C)(C)C2 +Cc1cc(CNC(=O)c2cscn2)ccc1S(C)(=O)=O +COc1ncc(C(=O)NCC(=O)Nc2ccccc2C)cn1 +CS(=O)(=O)c1ccc(CNC(=O)c2cnccn2)cc1 +COc1c(Cl)cc(NC(=O)Cn2cnnn2)cc1Cl +CCc1onc(C)c1NC(=O)NC1CCSc2c(F)cccc21 +CSc1nc2ccc3nc(NC(=O)c4ccoc4)sc3c2s1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1cn(CCC(C)C)nn1 +CCC(O)c1ccc(OCC2CCCCO2)cc1 +COc1ccc(CN(C(=O)c2ccc(F)cc2)C2CC2)c(OC)c1 +COc1ccccc1NC(=O)c1sc2ncccc2c1N +COc1c(S(=O)(=O)NCc2ccncc2)ccc(Cl)c1Cl +COc1ccc(-c2noc(CCC(=O)NC3CC3)n2)cc1OC +CCS(=O)(=O)N1CCC(Oc2cccnc2)CC1 +Cc1cccc(OC(=O)C(C)NC(=O)c2ccoc2)c1C +CC1CC1C(=O)NC1CCOc2c(Cl)cccc21 +Cc1ccn2ncc(C(=O)NCCC(=O)N3CCCC3)c2c1 +CN(C)S(=O)(=O)c1cccc(NC(=O)Cc2ccccc2F)c1 +CCS(=O)(=O)NCC1(c2ccc(F)cc2)CC1 +COc1cccc(Cn2c(=NC(=O)c3ccon3)[nH]c3ccccc32)c1 +COc1ccc2c(c1)nc(C(C)O)n2C(C)(C)CO +COc1ccc2c(=O)cc(C(=O)NCCc3ccccc3F)oc2c1 +COc1ccc(C2CC(O)=Nc3c2cnn3C)c(OC)c1 +CCOC(=O)NC1CCCN(C(=O)c2ccc(-n3ccnn3)cc2)C1 +COc1cccc(CNC(=O)c2cc(Cl)ccn2)c1 +CC(=O)N(Cc1ccco1)Cc1cc2ccccc2[nH]c1=O +COc1ccc(NC(=O)Nc2nnc(-c3ccsc3)o2)c(OC)c1 +N#Cc1cccc(NCCC(O)c2ccc(F)cc2)c1 +N#Cc1ccc(N2CCC3(CC2)CC(c2cccnc2)CO3)cc1 +O=S(=O)(NCc1nc(-c2cccs2)no1)c1cccs1 +Cc1cc(C)cc(NC(=O)c2nc3ccc(N)cc3o2)c1 +O=S(=O)(c1ccccc1Br)n1cccn1 +CC(C#N)NS(=O)(=O)c1ccc(C(C)(C)C)cc1 +Cc1cc(C)n2nc(C(=O)OCC(=O)N(C)C3CCCCC3)nc2n1 +CCN(CCCNC(=O)c1cc2ccccc2c(OC)n1)C(C)=O +CC(C)(C)n1cnnc1SCCCNC(=O)C1CCCC1 +CC(C)c1nc(CC(=O)Nc2ccc(C#N)cc2)cs1 +O=C(NCc1ccncc1)C1(c2ccc(F)cc2)CCCC1 +Cc1cnc(NC(=O)CNC(=O)C2COc3ccccc3O2)s1 +CCOc1ccc(F)c(C(=O)N(C)Cc2ccsc2)c1F +Nc1cc(Cl)ccc1NC(=O)c1ccsc1 +N#CCSc1ccccc1C(=O)Nc1ccc(F)cc1 +Cc1ccc(OC(C)C(=O)N2CCN(C)CC2)cc1C +CCCn1c(C(C)NC(=O)c2cccnc2)nc2ccccc21 +CCn1c(CCNC(=O)c2ccccc2)nc2cccnc21 +CC(Nc1ccccc1C#N)c1nc2ccccc2n1C +COCCN(C)C(=O)c1ccc(NC(C)=O)cc1 +Cc1cc(C)c(NC(=O)c2ccc(OC(C)C)nc2)c(C)c1 +Cc1ccc(OCC(=O)Nc2ccc(C)cc2N)cc1 +CCn1c(=O)c2ccccc2n(Cc2ccccc2C)c1=O +COc1ccc(NS(=O)(=O)c2cn[nH]c2C)cc1Cl +Cc1ccc2c(c1)NC(C)C(=O)N2CCCC(N)=O +O=C1CCc2cc(C(=O)Nc3ccccc3F)ccc2N1 +Cc1cc2ncn(CC(=O)N3CCc4ccccc43)c2cc1C +Cc1nn(C)c(C)c1CC(=O)Nc1ccc(F)c(C(N)=O)c1 +COc1cccc(-c2cc(NC3CC3)nc(C)n2)c1 +CCOc1cc(C)c(-c2cc(NC)ncn2)cc1C +CCC(=O)Nc1ccc(NCC(=O)NC2CCCCC2)cc1 +Cc1cc(NC(=O)c2cc3occc3n2Cc2cccc(F)c2)no1 +CN(C(=O)c1ccc2c(c1)OCCO2)C1CCc2ccccc2C1 +COCC(C)NC(=O)c1cc2c(=O)n3ccccc3nc2n1C +Cc1cccc(C(=O)NCC(=O)c2ccc3c(c2)OCO3)c1 +O=C(NCCCOc1ccc(F)cc1)c1cn2cccnc2n1 +COC1CCCC1OC(=O)Cc1c(C)nn(CC(C)C)c1C +N#CC1(COC(=O)c2occc2-c2ccccc2)CCOCC1 +Cc1ccc(C)c(OCC(=O)N(C)CC(=O)N2CCOCC2)c1 +Cc1cc(C)n2nc(SCc3coc(-c4ccccc4)n3)nc2n1 +COCCCNC(=O)N(C)Cc1nccn1C(F)F +Cc1nc2ccccc2nc1Cn1c(C#N)nc2ccccc21 +Fc1nc(F)c(F)c(-n2nnc3ccccc32)c1F +Cc1ccc(C(=O)NCCOc2ccc(C(F)(F)F)cc2)c(=O)[nH]1 +O=C(COC1CCCC1)Nc1nc2ccccc2s1 +CCc1noc2ncnc(Nc3ccccc3C(=O)OC)c12 +O=C(Nc1nnc(-c2ccc(F)cc2)o1)c1cccs1 +COc1ccc(OC)c(Nc2ncnc3onc(C)c23)c1 +Cc1noc(C)c1CN(C)CCc1nc(-c2ccc(Cl)cc2)no1 +O=C(Nc1ncccn1)C1CC=CCC1C(=O)Nc1ncccn1 +COc1ccccc1CN(C)C(=O)c1ccccc1 +CCC(=O)NC(c1ccccc1)c1ccc2nc[nH]c2c1 +CCN(CC)C(=O)c1ccc(NCc2nnc(C(C)(C)C)o2)cc1 +COC(=O)Nc1ccc(OC(C)C(=O)N2CCOCC2)cc1 +CCn1ccc(C(=O)N2CCC(CCOc3ccccc3)CC2)n1 +COc1ccc(CO)cc1OCc1cccc(Br)c1 +CC(=O)Oc1ccc(C(=O)Nc2cccc3cccnc23)cc1 +COc1ccc(C)cc1NC(=O)C(C)Sc1nnnn1C(C)(C)C +CC1=C(c2ccc(F)cc2)S(=O)(=O)N=C1N1CCN(C)CC1 +O=C1CCCN1c1cccc(-c2csc(-c3ccoc3)n2)c1 +Cc1nc2ccccc2n1CCNC(=O)CNC(=O)c1cccs1 +CCCNc1nc(-c2ccc(C)n(CCC)c2=O)cs1 +Cc1cc(C)nc(N2CCC(C(=O)NCCc3ccncc3)CC2)n1 +CC(=O)N1CCN(C(=O)Cc2c(C)noc2C)CC1 +CC1CN(C(=O)C2CC(=O)Nc3ccccc32)CC(C)O1 +CN(CC(=O)NC(C)(C)C)C(=O)NCC1CN2CCCCC2CO1 +COc1ccc(CC(C)CNC(=O)c2ccncc2)cc1 +Cc1cc(-c2nnc(CN(C)c3ccc(F)c(F)c3)o2)c(C)o1 +COc1ccc(C(=O)Cn2cc(N)cn2)c(Cl)c1 +Cc1noc(CN(C)Cc2cnc3cc(O)ccc3c2)n1 +COc1ccc(Cl)cc1N(C)C(=O)C1CCCO1 +Cc1ccc(-c2noc(C(C)NC(=O)c3cccnc3)n2)cc1 +Cc1ccc2ncc(C(=O)N(C)Cc3ncnn3C)n2c1 +CCNC(=O)c1ccc(NC(=O)c2ccc3c(c2)CCC(=O)N3)cc1 +COCCN1C(=O)c2ccccc2NC1c1ccc(SC)cc1 +O=C1CC(C(=O)N2CCc3ccccc3C2)CN1Cc1ccccn1 +COCCn1cc(NC(=O)c2cc(Cl)ccn2)ccc1=O +COCc1nn2c(-c3ccc(C(F)(F)F)cc3)nnc2s1 +CCc1nc(COC(=O)c2ccc(C)nc2C)cs1 +CCc1nc(Cn2cncc(Br)c2=O)no1 +CCCCc1nc2cc(C(=O)N3CCCN(C(C)=O)CC3)ccc2o1 +Cc1ccnc(NC(=O)c2cc3ncc(Br)cn3n2)c1 +COc1ccc(OC)c(C(=O)Nc2cccc(C(N)=O)c2)c1 +CC(=O)Nc1cccc(NCC(=O)NC2(C#N)CCCC2)c1C +Cn1c(SCCn2cccn2)nnc1-c1ccc(Cl)cc1 +COC(=O)Cn1cc(NC(=O)c2ccc(C)c(F)c2)cn1 +Cc1cccc(CN(C(=O)CCn2ccccc2=O)C2CC2)c1 +O=C(Nc1cc(Br)ccc1-n1cccn1)c1cnccn1 +O=C(c1ncccc1C(F)(F)F)N1CCN(Cc2ccccc2)CC1 +O=C(NCc1ccccc1)c1noc2ncnc(N3CCOCC3)c12 +COCCNC(=O)c1ccc(F)cc1Br +Cn1c(Nc2ccc3c(c2)oc(=O)n3C)c(C#N)c(=O)n(C)c1=O +CCc1n[nH]cc1C(=O)N1CCC(CNC(C)=O)CC1 +CCCc1sc(C(=O)NCCS(N)(=O)=O)cc1CC +CCOc1ccccc1C(=O)Nc1cc(C(=O)N(C)C)cn(C)c1=O +N#CC1CCN(C(=O)Nc2cccc(OCC(F)F)n2)CC1 +Cc1cc(-c2nn3c(-c4ccco4)nnc3s2)no1 +Cc1ccc2c(c1)CCCN2C(=O)NCc1nnc2ccccn12 +O=C(CCOc1cccc2ccccc12)n1ccnc1 +CCOCc1cccc(CNC(=O)NC(C)C2CC2)c1 +Cc1cc(C)n(-c2cccc(NC(=O)NCc3cccc(F)c3)c2)n1 +CC(C)OCCC(=O)N(C)C(C)c1cc(F)ccc1F +Fc1ccc(C2NCCc3cc(Cl)cc(F)c32)cn1 +CC1(C)CCCN1C(=O)Nc1ccc(F)cc1F +Nc1ccccc1OCCNS(=O)(=O)c1ccc(F)cc1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)OCc1ccccc1 +CC(=O)c1cnc(NCCc2cccnc2)nc1C +COCCNC(=O)CC1CC2CN(c3cc(OC)ncn3)CC2O1 +CC(=O)N1CCC(NC(=O)NCc2ccc(OC(F)F)cc2)CC1 +O=C(NCCC1=CCCCC1)NCc1ccc(-n2cncn2)nc1 +CCn1ncc(Br)c1C(=O)Nc1ccc(F)c(Cl)c1 +CC(=O)c1cc(CC(=O)NCc2c(F)cccc2F)cs1 +COC(=O)c1ccc(NC(=O)NCCc2cn3ccccc3n2)cc1 +O=C(Nc1c(F)cc(F)cc1Cl)c1cncc(Br)c1 +COc1cc(C(=O)NCc2ccccc2)cc(OC)c1OC +CCCNC(=O)COc1cccc(NC(=O)OC)c1 +O=c1cc(CNc2ccccc2Cl)[nH]c(=O)[nH]1 +Cc1ccccc1C1(C(=O)N2CCn3c(C)nnc3C2)CC1 +Cc1cc(CN2CCCC(c3nccs3)C2)ccc1F +NC(=O)c1csc(C(=O)Nc2ccccc2N2CCCC2=O)c1 +Cc1c(Cl)cccc1NC(=O)c1cc(F)cc2[nH]cnc12 +O=C(c1ccc[nH]1)N1CCCC(N2CCN(c3ccccc3)CC2)C1 +O=c1[nH]c2ccccc2n1-c1ccc(Br)cc1 +COC(=O)CNC(=O)C1CC(=O)N(c2ccc(C)cc2C)C1 +Cc1cc(-c2cccc3c2NCC3)c(C#N)c2c1NC(C)(C)C(O)C2C +N#Cc1ccccc1N1CCN(C(=O)c2ccc[nH]c2=O)CC1=O +N#CCCn1ncc2c(NCCc3cccs3)ncnc21 +COC1CCCC(OC(=O)c2ncn(-c3ccccc3)n2)C1 +O=S(=O)(Nc1ccc2c(c1)CCO2)c1ccccc1F +Cc1ccc(C)c(OCC(O)Cn2c(=O)n(C)c3ccccc32)c1C +COc1ccc(-n2cc(CNC(=O)c3ccccc3OC)nn2)cc1 +COCCc1nc(C)n(Cc2cccc(OC)c2)n1 +CC1CCC(N(C)C(=O)CC2Sc3ccccc3NC2=O)CC1 +Cc1nc(C2(NC(=O)CCC(=O)c3cccs3)CCCC2)no1 +O=C(NCc1ccc(Cn2ccnc2)cc1)c1cccc(F)c1F +CC1(C)OC(=O)N(CCc2c[nH]c3ccc(Cl)cc23)C1(C)O +CCCC(=O)Nc1cccc(N2CC(C(N)=O)CC2=O)c1 +COc1cccn(Cc2cc(C3CCCCC3)no2)c1=O +CN(C(=O)CSc1nnc(COc2ccccc2)n1N)C1CC1 +COc1ccccc1C(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O +CCNC(=O)c1ccc(NC(=O)c2cc3c([nH]c2=O)CCCC3)cc1 +CCc1nnc(SCc2ccccn2)n1C1CC1 +N#Cc1c2c(cn(CC3CCCO3)c1=O)CCCC2 +Cc1cc(C)nc(Nc2nc(C(=O)N3CCCCCC3)cs2)n1 +CC(=O)NCCCCCC(=O)N1CCCCCC1c1ccccc1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCC(=O)OC(C)(C)C)n1 +Cn1c2c(c(=O)n(C)c1=O)C(O)(C(F)(F)F)C(=O)N2 +CN(CC(=O)OCc1ccccc1)S(=O)(=O)c1ccc(F)cc1 +CCC(NC(=O)c1nc2nc(C)cc(C)n2n1)c1ccc(F)cc1 +Cc1ccccc1OCCC(=O)NCCc1ccccn1 +O=C(Cc1ccc[nH]1)NCCc1cc(Br)ccc1F +Cc1noc(C)c1CNC(=O)NCC(C)N1CCc2ccccc21 +CCCC1CCC(NC(=O)CN(C)C(N)=O)CC1 +Cc1ccc2nc(N3CCC(C(=O)N4CCOCC4)CC3)sc2c1 +CCOc1ccc(NC(=O)c2cc(C)n[nH]2)cc1C +O=S(=O)(NC1c2ccccc2CC1O)c1ccc2c(c1)CCO2 +O=C(Nc1ccccc1C(=O)N1CCOCC1)c1ccncc1 +CCC(CC)NS(=O)(=O)Cc1ccccc1Cl +COc1ccc(NC(=O)CCNC(=O)C(C)(C)C)cc1OC +C#Cc1cccc(NCc2cc(=O)n3nc(CC)sc3n2)c1 +COC(=O)C(C)NC(=O)N1CCc2cn(C)c3cccc(c23)C1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)N(C)Cc1ccccn1 +CCCS(=O)(=O)NC1CCN(Cc2nc(C)cs2)CC1 +CCc1noc(C)c1C(=O)Nc1cccc(C=Cc2ccccn2)c1 +COc1cccc(C(=O)N(C)C)c1OCC(C)C +Cc1nnnn1-c1cccc(NC(=O)CCn2ccccc2=O)c1 +COc1ccc(CC(C)CNC(=O)c2oc(C)nc2C)cc1 +CC(C)(C)CC(=O)NCC(=O)NS(=O)(=O)N1CCCC1 +CN(CC1CCCO1)C(=O)NCc1cccc(N(C)C)c1 +COc1ccc(S(=O)(=O)Nc2cc(C)on2)c(OC)c1 +CC1CCc2nc3ncn(CC(=O)NC4CC4)c(=O)c3cc2C1 +CCn1nc(CC2CC2)nc1Cn1nc2ccccc2n1 +Nc1ccnn1-c1ncc(C(F)(F)F)cc1Cl +CCCS(=O)(=O)Nc1ccc(N)c(C(F)(F)F)c1 +O=C(NCCC(=O)N1CCCCC1)c1ccc2sncc2c1 +CCCC(C)N(C)C(=O)c1[nH]c2c(c1C)C(=O)CCC2 +COCCOC1CCN(C(=O)NC(C)c2ccc(C)c(F)c2)CC1 +O=C(NC1CC1)c1cccc(OCc2ccc(-n3cccn3)cc2)c1 +Cc1ccc(NC(=O)Nc2ccc3[nH]c(=O)oc3c2)c(Cl)c1 +O=C(CNc1ccc(-n2cccn2)cc1)N1CCCc2ccccc21 +CCN(Cc1ccccc1)C(=O)Cn1nc(-c2cccs2)oc1=O +O=C(Nc1cnn(CCN2CCOCC2)c1)c1ccccc1F +Cc1ccsc1CNC(=O)c1cc(Cl)cn1C +CCNC(=O)CN1C(=O)COc2ccc(C(=O)N(C)C)cc21 +N#CC1(COC(=O)c2ccn(C3CCCC3)n2)CCOCC1 +Cn1ccc(NC(=O)c2ccnc(-n3cncn3)c2)n1 +Cc1occc1C(=O)N1CCN(C2CCc3c(Cl)cccc32)CC1 +Cc1nc[nH]c1C(=O)NC1CCCN(c2nc3ccccc3s2)C1 +COc1ccc(Cl)cc1CS(=O)(=O)c1ccc(N)cc1 +COc1ccc(NC(=O)NCC2Cn3ccnc3CO2)cc1 +CC(C)C1COC(=O)N1CC(=O)N(C)Cc1cccs1 +COc1cccc(C2NC(=O)c3ccccc3N2)c1OC(F)F +Cc1cc(C(=O)N2CC(n3ccnn3)C2)c(C)n1Cc1ccccc1 +CS(=O)(=O)N1CCCCC1C(=O)Nc1ccc2sccc2c1 +COc1ccccc1N1CCN(C(=O)NC(C)CCCO)CC1 +COc1ccc(-c2noc(CCC(=O)NC3CCCC3)n2)cc1 +CC1CCCC(Oc2nc3c(c(=O)n(C)c(=O)n3C)n2C)C1 +CC(C)c1ccc(-c2nnc(NC(=O)NCCO)s2)cc1 +Cc1ccc(OCC(=O)Nc2cccc(C(N)=O)c2)c(C)c1 +CN1CCc2nc3c(Cl)cccc3c(C#N)c2C1 +COc1ccccc1C(=O)N1CCN(c2ncnc3[nH]cnc23)CC1 +CCC(=O)NCC(=O)NC(C)c1ccc(NC(=O)C2CC2)cc1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)N1CC(C)OC(C)C1 +COc1ccc(NC(=O)C(C)CC2CCCC2)cc1S(N)(=O)=O +N#Cc1c(NC(=O)Cc2ccc(F)cc2)sc2c1CCC2 +COCCCC(=O)N1CCN(C(=O)c2ccc(Cl)cc2F)CC1 +Cc1cnc(C(=O)N(Cc2ccco2)c2ccc(F)cc2F)cn1 +O=C(CC1CCCC1)NC1CCN(C(=O)Cc2ccc[nH]2)CC1 +CCCn1c(=O)n(CCC)c2cc(N(CC)CC)c(N)cc21 +Cc1cc(NC(=O)c2nonc2C)n(Cc2ccccc2)n1 +CS(=O)(=O)c1ccc(NC(=O)C2CCCc3ccccc32)cc1 +CN(c1ccc(F)c(F)c1)S(=O)(=O)c1ccccc1C#N +O=C(CSc1ccc(F)cc1)OCCN1CCCC1=O +Cc1ccc(NC(=O)N2CCC(C(N)=O)CC2)cc1 +Cc1ccccc1NC(=O)Cc1noc2ccccc12 +O=C(OCc1nnnn1-c1ccccc1)c1ccccc1Cl +CC(=O)c1cccc(NC(=O)c2ccc3nccnc3c2)c1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1ccccc1-n1cnnn1 +O=C(Nc1ccccc1)N1CCN2C(=O)C3CCCN3C(=O)C2C1 +COc1cccc(NC(=O)Nc2ccc(OC)c(OC)c2)c1 +CCn1c(SCC(=O)C(C)(C)C)nnc1C1CC1 +COCC(=O)N1CCc2onc(-c3ccccc3F)c2C1 +COc1ccc(CCc2nc(C3CC3)n(C)n2)cc1N +O=S1(=O)CCCN1C1CNc2ccccc2C1 +Cc1cc(C)cc(-c2nnc(SC(C)C(=O)NC3CC3)o2)c1 +Cc1cc(C(=O)Nc2ccccc2C(N)=O)c(C)n1Cc1ccco1 +Cc1cccc(C(N)=O)c1NCc1cccc(C(=O)N(C)C)c1 +CCOC(=O)c1sc2ncn3ncnc3c2c1C +O=C(Cn1cnnn1)N1CCCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1ccc(C(=O)Nc2ccc(CC#N)cc2)s1 +COc1cccc(NC(=O)c2cc3cccnc3[nH]c2=O)c1 +O=C(NCCC(=O)N1CCCc2ccccc21)c1ccsc1 +Cc1cc(C(=O)NC2CCCC2)c2ccccc2n1 +CC(C)CC1COCCN1CC(=O)NC(C)C(C)C +NC(=O)C(NC(=O)C1CC1c1cccc(Cl)c1)c1ccccc1 +Cn1c(N)c(C(=O)COc2cccc3c2CCC3=O)c(=O)n(C)c1=O +Cc1ccc(C(=O)Nc2cc(-c3cccs3)n[nH]2)cc1F +CCOCC1CCCN(C(=O)Nc2ccc3c(c2)OCO3)C1 +CN(C)c1ccc(-c2cnc3c(c2)CC(=O)N3)cc1 +CC(C)NC(=O)CSc1nnc2n1C(C)(C)Cc1ccccc1-2 +Cc1onc(-c2ccccc2)c1C(=O)N1CCC(O)CC1 +CCCC(C(=O)Nc1cccc(C#N)c1)n1ccc(C)cc1=O +O=C(NCc1cn2cc(Cl)ccc2n1)c1scnc1C1CC1 +O=C(c1cc(=O)c2ccccc2o1)N1Cc2cnn(CCO)c2C1 +O=C(NC1CCc2c(O)cccc21)C(Cc1ccccc1)n1cnnn1 +CC(C)C(NC(N)=O)C(=O)Nc1cccc(N2CCCCCC2)c1 +Cc1ccc(C(=O)N2CCCCC2CNC(N)=O)cc1F +O=C(Nc1ccc(CC(=O)N2CCCC2)cc1)c1ccc(Cl)cc1 +CCN(CC)c1ncnc(NCCc2ccccc2)c1N +O=C(CCNC(=O)C1CCCCC1)Nc1ccccn1 +Cc1ccc(NC(=O)Cn2nnnc2C(C)(C)C)cc1 +COCC(c1ccnn1C)n1cc(-c2nccn2C)nn1 +CNC(=O)c1cccc(CCNC(=O)c2c(C)[nH]c3ccccc23)c1 +CCOCCNC(=O)c1c(C)nn(-c2ccccc2)c1C +O=C(c1c[nH]cn1)N1CCC(F)(F)C2(CCN(c3ncccn3)C2)C1 +CC(C)c1noc(CCC(=O)NCc2cccs2)n1 +Cc1ccnc(Nc2nc(CC(=O)NCC(N)=O)cs2)c1 +Cc1cc(C)n(CCn2cc(C3CCOC3)nn2)c(=O)n1 +Cc1ccc(C(=O)NCCc2ccccc2)cc1O +CCOc1ncccc1CNC(=O)c1ccc[nH]c1=O +N#Cc1cc2c(nc1SCC(=O)Nc1ccccc1F)CCC2 +COc1ccc(N(C)C(=O)c2cc3ccccc3[nH]2)cc1OC +CC(C)C(=O)c1ccccc1NC(=O)c1ccco1 +C=CCn1c(=O)c2c(nc3n(CCO)c(C)cn23)n(C)c1=O +Cc1ccc(-n2nnc(-c3nc(-c4cccs4)no3)c2N)cc1C +CCOC(=O)C1(NC(=O)Cc2c(C)[nH]c3ccnn3c2=O)CCCC1 +CS(=O)(=O)c1nc2ccccc2n1Cc1ccccc1F +O=C1COc2ccc(NC(=O)c3scnc3C3CC3)cc2N1 +Cn1ccc(NC(=O)c2cccc(OCC3CCCO3)c2)n1 +CCn1nnc2cc(C(=O)Nc3c(C(N)=O)oc4ccccc34)ccc21 +Cc1ccc2nc(C3CCCN3C(=O)Cc3cc(C)no3)[nH]c2c1 +N#Cc1ncn(CC(O)COc2ccccc2N)n1 +CN(C)C(=O)c1cccc(C(=O)Nc2ccc(F)cc2)c1 +Cc1c(N2CCN(C(=O)c3ccco3)CC2)c(=O)n(C)c(=O)n1C +Cc1ccccc1CCNC(=O)C(C)Nc1ccc2[nH]c(=O)[nH]c2c1 +CCCOCc1ccccc1CNc1nc2c(cnn2C)c(=O)[nH]1 +CN1CCc2nc3ccc(Cl)cc3c(C#N)c2C1 +CCOC(=O)CN(C(=O)c1cc(Cl)cc(Cl)c1)C1CC1 +CCc1ccc(CNC(=O)c2nc3cccnc3n(CC)c2=O)cc1 +COc1ccc(C(=O)OC(c2ccccc2)c2ccccn2)nn1 +Cc1cc(NC(=O)C(C)(C)C)sc1C(=O)C(C#N)c1ccccn1 +CNc1nc(-c2cnc(C3CCCCC3)s2)cs1 +Cn1cc(CNC(=O)NCCOc2ccc(F)c(F)c2)cn1 +O=C(Cc1ccsc1)N1CC(OCc2cccnc2)C2COCC21 +O=C(COc1ccccc1Cl)c1ccc(N2CCCC2=O)cc1 +Cn1cnc(CNC(=O)NCc2ccn(-c3c(F)cccc3F)n2)n1 +COCc1nc2ccccc2c(=O)n1-c1ccc(F)cc1 +CS(=O)(=O)N1CCC(Oc2ccc(-c3ccsc3)cc2)CC1 +Cc1cccc(-c2nc(CN3CCOCC3)c(C)o2)c1 +O=C(CCc1cccc(F)c1)Nc1cc2c(cc1Cl)NC(=O)CO2 +CC(C)c1cc(N(C)Cc2nc3cc(Cl)ccc3[nH]2)ncn1 +Cc1ccc(NC(=O)c2cc(S(N)(=O)=O)c(C)o2)cc1Cl +COc1c(F)cc(NC(=O)Nc2nccs2)cc1F +Cc1cc(C(=O)CSc2nc(N)c3ccsc3n2)c(C)[nH]1 +CC1CCCC(C)N1C(=O)COC(=O)c1ccc2ccccc2n1 +O=C(NCC1CCCC1O)c1cn(Cc2ccccc2)nn1 +CC(=O)c1c(O)cc(C)n(Cc2cccnc2)c1=O +Cc1cc(NC(=O)C2COc3ccccc3O2)n(C)n1 +COc1cc(NC(=O)c2ccc(-n3cccn3)cc2)cc(OC)c1 +CN(CCC(F)(F)F)C(=O)CNC(=O)C1CCCC1 +CC1CN(C(=O)NCCCNC(=O)c2ccc(F)cc2)CC(C)O1 +O=C(NCc1cccc(F)c1)c1cc2n(n1)CCCO2 +O=C(COc1ccccc1F)Nc1cccc2cnccc12 +COCC(NC(=O)C1CC1c1cccc(Cl)c1Cl)C(N)=O +CCC(=O)N1CCN(c2cc(N)nc(N)n2)CC1 +Cc1ccc(N)c2nnc(-c3cccc(Br)c3)n12 +CC(C)(C)n1c(=NC(=O)Cn2ccccc2=O)[nH]c2ccccc21 +CC(C)(C)c1ccc(C(=O)CCN2CCOCC2)cc1 +C=C(C)Cn1c(CCNC(=O)COC)nc2ccccc21 +COC(=O)c1c(C)[nH]c(C(=O)Nc2cc(C)nn2CCC#N)c1C +Cc1ccc(Nc2n[nH]c(N)c2NC(=O)c2ccccc2)cc1 +COC(=O)c1c(-c2cc(F)ccc2OC)noc1N +O=C(Nn1cnc2c(cnn2-c2ccccc2)c1=O)C1CC1 +NS(=O)(=O)c1ccc(C(=O)Nc2cccc(F)c2)o1 +CCOC(=O)C1CN(S(C)(=O)=O)Cc2ncn(CC)c21 +CC(C)CC(=O)NC(c1ccc2c(c1)OCCO2)C1CC1 +Cc1nc2nc(C)c(C(=O)N3CCOCC3)cn2n1 +Cc1scc2nc(C(=O)N3CCN(C)CC3)nc(N(C)C)c12 +O=c1[nH]nc(N(CCO)Cc2ccccc2)c(=O)[nH]1 +CC(=O)Nc1cccc(CNC(=O)Cc2ccc(C)nc2)c1 +COc1ccc(CNc2ccc(NC(C)=O)cc2)c(OC)c1OC +CCOC(=O)N(C)c1ccc(NCc2ccc3c(c2)OCCO3)cc1 +CN(Cc1nc2ccccc2[nH]1)S(=O)(=O)N1CCOCC1 +Cc1occc1COC(=O)CCNC(=O)C(C)(C)C +CCC(CO)NC(=O)c1cc(S(=O)(=O)NC)cn1C +C=CCOC(=O)C1CCN(S(=O)(=O)c2cccnc2)CC1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1cn[nH]c1 +CNC(=O)CNC(=O)CCn1ncc2cc(C)ccc21 +COCCNC(=O)NCC#Cc1ccccc1OC +Fc1cccc(-c2nc3cnccn3c2NCc2ccco2)c1 +Cc1cccc(OCC(=O)Nc2cccc3ncccc23)c1 +CCOc1ccc2nc(NC(=O)CNC(=O)NC)sc2c1 +OC(Cn1cnnc1)c1ccc(C(F)(F)F)cc1 +CN(CCO)C(=O)c1cc(=O)c2cc(N)cc(Cl)c2o1 +CC(Sc1ccc(C(F)(F)F)cn1)C(N)=O +CC(OCC1CCN(C(=O)OC(C)(C)C)C1)c1ccccn1 +CC(C)CCNS(=O)(=O)c1ccc(Cl)cc1F +CC1CN(Cc2coc(-c3cccc(Cl)c3)n2)CC(C)O1 +CC(CNc1ncccc1S(N)(=O)=O)Cc1cccs1 +CCN(C(=O)CN(C)c1ccc(N)cn1)c1ccccc1 +NC(=O)c1ccc(Oc2ccccc2Br)cc1 +O=C(Nc1ccccc1Cl)c1ccc(N2CCOCC2)cc1 +CCc1ccccc1N1CC(C(=O)NCc2ccccn2)CC1=O +Cc1nn(C)cc1C(=O)N(C)Cc1c(C)nn(C)c1C +COCCCNC(=O)Cc1ccc(N2CCCC2=O)cc1 +COC(=O)CCCS(=O)(=O)N(C)c1cc(C)ccc1C +CCNc1ccc(C(=O)OCC)cc1NC(=O)c1cccs1 +Cc1nc(Sc2nnc(C3CC3)n2C2CC2)c2cc[nH]c2n1 +CCCNc1snnc1CN(C)c1ccc(F)cc1 +O=C(NCC1CCN(C(=O)c2ccoc2)CC1)C1CCCC1 +Cc1occc(=O)c1OCc1ccc(Cl)cc1Cl +O=C(NCc1cccnc1)c1cc(-c2cc[nH]n2)n2ccccc12 +Cc1nc(C(=O)NCc2ccc(C#N)cc2)cs1 +COc1ccc(OC)c(NC(=O)c2ccc3snnc3c2)c1 +Cc1sc(=O)n(CC(=O)Oc2ccc(C(=O)OC(C)C)cc2)c1C +O=C(CSc1nnnn1C1CCOCC1)Nc1ccccc1 +CC(C)N(C(=O)COc1cccc(C(N)=O)c1)C1CCCCC1 +N#Cc1ccc(Cn2nc(-c3cccs3)oc2=O)cc1 +Cc1oc(-c2ccsc2)nc1CC(=O)N(C)CCC(F)(F)F +COC(=O)c1cccc(C(=O)N2CCC(=O)NCC2C)c1 +O=C(CCCc1ccccn1)NCc1nc2ccc(F)cc2[nH]1 +O=C(CCC(=O)N1CCOc2ccccc21)NCc1cccs1 +O=C1CCCCCN1CC(=O)N1CCCC(n2cncn2)C1 +Cc1cccc(NC(=O)C2CC(=O)N(c3cccc(Cl)c3)C2)n1 +COc1ccccc1-c1cc(=O)oc(-c2cccs2)n1 +O=C(NCc1nnc2n1CCC2)Nc1ccccc1F +Cc1ccc(C(=O)N2CCCC(S(=O)(=O)N3CCOCC3)C2)o1 +CC(O)CN1CCN(C(C)C(=O)NCc2ccco2)CC1C +O=C(c1cccc2ccccc12)N1CCC(n2cncn2)CC1 +COCCNC(=O)C1CCN(c2cccc(F)c2)C1=O +NC(=O)CSc1nnc(-c2ccco2)n1-c1ccc(Cl)cc1 +Cc1nnc(N2CCC(C(O)CCc3ccccc3)CC2)o1 +CCOC(=O)c1cnn2c(C(=O)N(C)c3cccc(C#N)c3)ccnc12 +Cc1nc2c(O)c3c(=O)n(C)c(C)nc3c(O)c2c(=O)n1C +CC(=O)c1cc(F)ccc1N1CCC(C(N)=O)CC1 +O=C(NCc1ccncc1)Nc1cccc(Cn2cccn2)c1 +CC(C)c1ccccc1NC(=O)NCc1nnc2n1CCC2 +CCc1nc2n(n1)C(CC(=O)Nc1ccc(F)cc1)C(=O)N2 +Cc1nn(C)c(C)c1S(=O)(=O)NCc1cscn1 +Nn1c(Cc2ccccc2)nc2sc3c(c2c1=O)CCCC3 +CCCCCCN1CC2(CCN(C(=O)c3cc[nH]n3)CC2)OC1=O +O=C(Nc1nc(-c2ccco2)cs1)c1ccnc(-n2cncn2)c1 +COC(=O)C(O)(NS(=O)(=O)c1ccccc1)C(F)(F)F +COC(=O)NCC(=O)N1CCCC1Cc1ccccc1 +COc1ccc(C(=O)CNc2ccccc2C)cc1OC +O=C(Nc1ccccc1O)c1cc(F)ccc1Br +NC(=O)C1(CNC(=O)Cc2ccc(OC(F)F)cc2)CCOCC1 +O=C(CC1COC(=O)C1)NC(CC(F)(F)F)c1ccc(F)cc1 +Nc1ccccc1NS(=O)(=O)c1sccc1Br +CCN(CC)C(=O)N1CCC(C(=O)OC(C)c2nc(C)no2)CC1 +CCNc1nc(SC(C)C(=O)NC)nc2ccccc12 +Cn1ccc(C(=O)CN(CC(F)(F)F)C2CC2)c1 +O=C(Nc1ccc(CC(=O)N2CCCC2)cc1)c1cccnc1 +COC1CCC(c2ccccc2F)n2nc(N)nc21 +Cc1csc(-c2cccc(NCC(=O)NCC(F)(F)F)c2)n1 +O=C(NC1CCCc2ccccc21)c1sccc1-n1cnnn1 +COc1ccc(C(C)COC(=O)C(C)NC(C)=O)cc1 +Cn1nc2cccc(NC(=O)NCc3nnc4n3CCC4)c2n1 +Nc1cc(CCc2ncc3c(n2)CCC3)ccc1F +O=C(Cc1cn2ccsc2n1)NCc1ccncc1 +CCOc1ccc(Br)cc1C(=O)N1CCOCC1 +Cc1ccc(C(=O)NCCNC(=O)c2ccc[nH]2)cc1F +CN(C)c1ncccc1C(=O)Nc1cccc(OCC2CCCO2)c1 +O=C(Nc1ccc(C2=NCCO2)cc1)c1cccc(F)c1 +COCCCNC(=O)C(C)Nc1ccccc1F +CC1CN(C(C)CNC(=O)C(C)OCc2ccccc2)CC(C)O1 +Cc1cc(CNC(=O)CCCc2ncc(-c3ccccc3)o2)c(C)o1 +NS(=O)(=O)NC(Cc1ccccc1)c1ccccc1F +O=C1OCCC1N1CCCN(S(=O)(=O)c2ccccc2)CC1 +CCCNC(=O)CSc1nnc2c(n1)[nH]c1ccccc12 +CN(c1ccc(C(=O)N2CCCCCC2)c(Cl)c1)S(C)(=O)=O +COc1ccnc(N2CCN(C(=O)C3COCCO3)CC2)n1 +CCc1cc(NC(=O)c2cc(OC)c(OC)cc2C)[nH]n1 +CC(C)CNC(=O)C(N)c1ccc(C(C)(C)C)cc1 +Cc1ccc(CC2Oc3ccc(O)cc3NC2=O)cc1C +C=CCOc1cccc(NC(=O)CNC(=O)c2cc(F)cc(F)c2)c1 +CC(C)CC(NC(=O)CNC(=O)c1ccoc1)c1cccs1 +CCOc1ccc2nc(NC(=O)c3cc4n(n3)CCCO4)sc2c1 +c1ccc(Nc2ccnc(C3COCCN3CC3CC3)n2)nc1 +CC(C)N(C)S(=O)(=O)N(C)Cc1cc(Cl)cc(Cl)c1 +COc1cccc(-c2cc(C(=O)NCC3COCCO3)[nH]n2)c1 +CCCCNC(=O)c1ccc(CS(=O)(=O)c2ccc(C)cc2)o1 +CCOC(=O)Cc1nnc(NC(=O)N2CC(C)CCC2C)s1 +COc1ccc2nc(C(=O)NCc3ccc4c(c3)OCO4)cn2n1 +CCOC(=O)Nc1cc(OC)c(OC)cc1C(=O)OC +C#Cc1cccc(N(CC(=O)N2CCOCC2)C(=O)CC2CCC2)c1 +O=C(CSc1nnc(-c2ccco2)n1C1CC1)Nc1nccs1 +COC(C)(C)c1noc(-c2ccc3[nH]c(=O)c(=O)[nH]c3c2)n1 +CC1(C)CCCC2(C)C3=C(C(=O)OC3O)C(O)CC12 +O=C(Nc1ccc(O)cc1)C(O)C(O)C(O)C(O)CO +O=C(NCCCn1ccnc1)c1ccn(C2CCCC2)n1 +CNC(=O)C1Cc2ccccc2N1S(=O)(=O)c1cccs1 +CCCC1CN(C(=O)C2CCCN(C(=O)NCC(C)C)C2)CCO1 +CC(=O)Nc1ccccc1OCC(=O)NC1(C#N)CCCCC1 +COc1ccc(C(O)(c2cncnc2)C2CC2)cc1 +Cc1cccc(O)c1NCc1cc(C#N)ccc1F +COc1ccccc1CC(=O)Nc1ccc(Br)cn1 +O=C(NCC1CCN(c2ncccn2)CC1)c1ccc(Cl)cc1 +Fc1ccccc1-c1cnc(CNCc2cccnc2)s1 +Clc1ccccc1-c1nnc(Cn2nnc(-c3ccsc3)n2)o1 +CC(CNC(=O)Cn1c(=O)[nH]c(=O)c2ccccc21)N1CCOCC1 +CNC(=O)c1cccc(OC(=O)Cc2cccc(C(F)(F)F)c2)c1 +O=C(CS(=O)c1ccc(F)cc1)Nc1ccc(Cl)cc1Cl +CC(=O)Nc1nc(C(F)(F)F)c(-c2ccccc2)s1 +CCOc1ccc(NC(=O)CCn2nc(C)c(C)c2C)cc1 +CCOc1ccccc1OCC(=O)Nc1cccn(C)c1=O +CC(C)(C)CC(=O)N1CCc2onc(-c3ccc4c(c3)OCO4)c2C1 +Cn1c(=O)c2c(nc(N3CCCCCC3)n2CC(N)=O)n(C)c1=O +O=C(Nc1cccc2c1CCCC2)c1ccc(=O)[nH]c1 +CC(CNC(=O)N(C)Cc1ccccn1)N1CCc2ccccc21 +COc1ccc(NC(=O)c2cnc3cc(C)ccn3c2=O)c(Cl)c1 +COc1ccc(CNS(=O)(=O)c2c(C)noc2C)cc1 +COc1ccc(-c2csc(NC(=O)c3ccno3)n2)cc1 +O=C(NC1CCCN(C(=O)c2ccco2)C1)c1cc(C2CC2)n[nH]1 +Nc1c(NCc2cccnc2)ncnc1Nc1ccc(F)cc1 +CC(=O)c1ccc(OC(=O)C2CCCN(C(=O)c3ccoc3)C2)cc1 +CC1CCCCC1NC(=O)CNc1ccccc1C(N)=O +COc1cccc(OC)c1C(=O)N(C)C1(C#N)CCCCC1 +COc1ccc(CN2CCN(C(=O)CCn3cnnn3)CC2=O)cc1 +Cn1cc(Br)cc1C(=O)Nc1ccc2ncccc2c1 +COc1ccc(CCC(=O)Nc2ccc3c(c2)COC3)cc1F +O=C(COc1ccccc1Cl)NCCNC(=O)c1ccncc1 +CC(=O)N1CCN(c2nc(C)c3c(c2C#N)CC(C)(C)OC3)CC1 +CC(=O)NCc1ccc(C(=O)N(c2nc(C)cs2)C2CC2)cc1 +Cc1ccnc(-n2c(SCCC#N)nc3ccccc3c2=O)c1 +Cc1occc1-c1nnc(SCC(=O)Nc2ccccn2)o1 +COC(=O)c1ccc(F)c(NCC(=O)NC2CCC(C)CC2)c1 +CC(C)(C)OC(=O)N1CCC(C(=O)NCCc2ccco2)CC1 +COCc1ccc(CNS(=O)(=O)c2cccc(F)c2)cc1 +CCc1onc(C)c1NC(=O)NC(C)CCc1cccn1C +Cc1ccc(NC(=O)N2CCCC(NS(C)(=O)=O)C2)c(C)c1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2cc(C)ccc2C)cc1 +CC(C)=CC1C(C(=O)Nc2ncccc2OCCCC#N)C1(C)C +CCn1cc(Cl)c(C(=O)Nc2ccc(OC(F)(F)F)cc2)n1 +COc1cccc(C(=O)NCc2cc(Br)cs2)c1F +NC(=O)c1ccc(COc2ccc(Cl)cc2N)c(F)c1 +Nc1cc(Br)ccc1OCC(F)(F)F +Nc1ccc(-c2nnn(CC(=O)Nc3ccc(F)c(Cl)c3)n2)cc1 +Cc1nc(-c2cccc(C(=O)N3CCN(c4ccccc4)CC3)c2)no1 +COc1ccccc1OCC(=O)NC1CCCCCC1 +Nc1cc(Br)cnc1NCCc1ccccc1 +COc1ccc(NC(=O)NCc2ccccn2)cc1NC(C)=O +O=C(CCOCC1CCCO1)Oc1cccc(Br)c1 +CC1=CC(C)(C)n2c(=O)oc(=O)c3cc(C)cc1c32 +O=C(NCC1(c2ccc(Cl)cc2)CCOCC1)Nc1ccncc1 +Cn1cc(Br)cc1C(=O)Nc1ccc(F)c(C(N)=O)c1 +Cc1cnc(C(=O)N2CCC(NC(=O)c3ccccc3)CC2)cn1 +CCOC(=O)CCc1cc(OC)ccc1Br +COC(=O)c1cccc(C(=O)Nc2cnn(C)c2)c1 +Cn1nc(CNC(=O)c2cccc(F)c2)cc1-c1ccccn1 +CCOC(=O)c1csc2nc(-c3cccnc3)c(N)n12 +Cc1ccc(NC(=O)c2ccc(C)c(C)c2)c(OCC(=O)N(C)C)c1 +O=C(c1cc(-c2ccccc2)[nH]n1)N1CCCC1c1ccc[nH]1 +CC1CCC(C(N)=O)CN1C(=O)C1CC1c1ccco1 +COc1ccc(F)c(NC(=O)C2CCOc3ccccc32)c1 +O=c1[nH]c(=O)n(CCCCCO)cc1Br +CCCN(CC1CC1)C(=O)c1ccc(-c2ccccc2)[nH]c1=O +N#CCOc1cccc(CC(=O)Nc2ccccc2C(N)=O)c1 +COC(=O)C1CCCN1c1nccc2c(N)cc(C)cc12 +CCSc1ccc(NC(=O)c2c(F)cccc2F)cn1 +CCOc1ccc(Cl)cc1CNc1ccon1 +Cc1ccc2cccc(OCc3nccs3)c2n1 +CCc1n[nH]c2c1CN(c1nnc(C(C)(C)C)o1)CC2 +C#CCOC(=O)c1cc(S(=O)(=O)N(C)C)c(C)o1 +COc1cccc(COC(C)C(=O)Nc2ccccc2C(C)=O)c1 +CNS(=O)(=O)c1cccc(CNC(=O)Nc2cc(C)on2)c1 +COc1ccc(N2CC(C(=O)NCCCn3cccn3)CC2=O)cc1 +COc1ccc(C(=O)Nc2ccc(C)c(OCC(F)F)c2)nn1 +COCc1nc(N2CCC(C)CC2)sc1CC#N +CCC1CCCCN1C(=O)c1cccc(Oc2nccc(C)n2)c1 +CC(CNS(=O)(=O)CC1CCCCC1)N1CCOCC1 +CC(C)(CNC(=O)c1ccc[nH]1)c1ccccc1F +O=C(Nc1ccc2nc(CO)[nH]c2c1)c1ccc(F)cc1 +CNc1ncccc1S(=O)(=O)N(C)CC(C)C +N#CC(CCC(=O)NCc1ccncc1)c1cccc(F)c1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NC(C)(C)C)[nH]n1 +CCS(=O)(=O)NCCNS(=O)(=O)c1cc(C)ccc1C +CC(C)N(C)S(=O)(=O)c1cccc(C(=O)NCc2ccccc2)c1 +CCc1ccc(CNC(=O)Nc2ccnn2C(C)C)s1 +O=S(=O)(CCSc1ccccn1)c1nc2ccccc2s1 +O=C1c2cccnc2C(O)N1Cc1ccc(F)cc1 +O=C(NCC1CCOc2ccccc2C1)c1cccc(-n2cnnc2)c1 +COCC(C)Nc1nc(Nc2ccc(F)cc2)c2cn[nH]c2n1 +CC(C)Cc1cc(CNC(=O)c2cc(=O)n(C)c(=O)n2C)on1 +Cc1cccc(Nc2nc(N)nc(C(F)(F)F)n2)c1C +O=C(Nc1ccccc1)c1cc2ccc(O)cc2oc1=O +CC(=O)N1CCCN(CC(=O)c2c(N)n(C3CC3)c(=O)[nH]c2=O)CC1 +CNc1nc(C(N)=O)c(NC(=O)c2c(F)cccc2F)s1 +CC1=COC(C)(CN(C(=O)C2CC2)C(C)C)CC1 +Cn1cc(C(=O)OCC(=O)NC(C)(C)C)c2ccccc21 +CC(Nc1nnc(C(F)(F)F)s1)C(=O)N1CCc2ccccc21 +CN(C)c1ccc(C(=O)OCC(=O)N2CCCC2)cc1 +Cc1ccc(CN2CC3CC(C(=O)NCC(C)C)C(C2)O3)o1 +COC(=O)C1=C(C)N(Cc2ccc3c(c2)OCO3)C(=O)C1 +CC(C(=O)N1CCCC1)n1cnc2ccccc2c1=O +CC(C)C(NC(=O)N(C)C(C)C)c1nnc2ccccn12 +O=c1c2ccc(F)cc2ncn1Cc1ncc(Cl)cc1Cl +Cn1c(=O)oc2cc(NC(=O)NCCC3=CCCCC3)ccc21 +Cc1c(C(=O)NCCOc2ccccc2)nc2c(Cl)cccn12 +CC(=O)NC(CC(=O)Oc1ccc(C#N)cc1)c1ccc(C)cc1 +Cc1cc2c(SCC(=O)NCc3ccccc3F)ncnc2s1 +Cc1nnsc1C(=O)Nc1cnn(CCc2ccccc2)c1 +O=S(=O)(CCCO)NCc1ccc(Cl)c(Cl)c1 +O=C(NC1CC1)C1CCCN1c1ncnc2c1cnn2-c1ccccc1 +O=C(NC1CCCCCC1)C1CCCN1C(=O)c1cccs1 +Cc1noc(CCC(=O)N(C)CCc2ccc(F)cc2)n1 +Cc1cc(C(=O)Nc2nc(-c3cccs3)cs2)on1 +Cc1cc(C)cc(NC(=O)NCc2cnc(C)s2)c1 +COc1ccc(OC)c(NC(=O)c2cc(=O)c(OC)co2)c1 +C#CCN1CCC(C(=O)Oc2c(C)cc(C)cc2C)CC1 +CCC(=O)C(C)n1cnc2c1c(=O)n(C)c(=O)n2C +COc1ccsc1C(=O)N1CCCC1CC(=O)c1ccccc1 +Cc1nc(C(=O)Nc2ccc(-c3nnco3)cc2)cs1 +CCOCCCNC(=O)c1nn(CC)c2ccc(Cl)cc2c1=O +CC(C)(O)CNC(=O)c1c(Cl)ccc(Cl)c1Cl +CC(=O)N1CCc2ccc(S(=O)(=O)N3CCC(C)CC3)cc2C1 +CC(=O)Nc1cccc(NCc2cccc(C)c2)c1 +COc1ccccc1CCNC(=O)Cc1n[nH]c(=O)c2ccccc12 +CC(CNC(=O)c1ccc(-c2ccccc2)[nH]c1=O)N1CCOCC1 +Cc1noc(C)c1NC(=O)NCc1cccs1 +CC(=O)N(CCC(=O)NC(C)C(=O)N(C)C)Cc1ccccc1 +CC(C)N(CCO)Cc1nc2ccccc2c(=O)[nH]1 +Cc1ccc(NCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1C +CC(=O)Oc1ccccc1C(=O)Nc1cc(C)on1 +O=C(Nc1ccccc1N1CCCCCC1)c1cc[nH]n1 +CCCc1cc(C(N)=O)c(NC(=O)c2ccoc2C)s1 +CC(C)n1c(C2CCCN(C(=O)c3ccc(=O)[nH]c3)C2)nn(C)c1=O +COC(=O)N1CCC(NC(=O)NCC2CCCO2)CC1 +CC(C)(C)C(=O)NCCC(=O)Oc1ccc(C#N)cc1 +Cc1ccn2c(=NC(=O)CCc3ccncc3)[nH]nc2c1 +COC(=O)c1ccc(C(=O)N2CC(C)OC(C)C2)nc1 +CN(Cc1ccc(Cl)cc1)C(=O)c1ccc(-n2cncn2)nc1 +COCC1CCCN(C(=O)c2cc(-c3cccs3)n[nH]2)C1 +CCCOc1ccc(CN2CCN(C(=O)C3CCC3)CC2)cn1 +CCc1ncc(C(=O)NCCNC(=O)c2ccc(C)c(F)c2)s1 +COc1ccc(OC(=O)c2cn(C)c(=O)c3ccccc23)cc1 +CCOC(=O)CN1C(=O)C(C)Nc2cc(OC)ccc21 +CNC(=O)COc1ccc(CC2COc3c(cccc3OC)C2)cc1 +O=C(NCC(=O)N1CCCCC1)c1ccc(Cl)cc1O +Cn1ncc(C(=O)Nc2ccc(Cl)cc2)c1N +Cc1noc(C2CN(S(=O)(=O)c3cccnc3)C2)n1 +CCc1nc(CC(=O)Nc2cnccc2Oc2ccccc2)cs1 +CCCCN(C(=O)c1ccc(=O)n(-c2ccccc2)n1)C(C)CC +Cc1ccc(S(=O)(=O)N(C)C(C)C)cc1NC(C)C +CC(C)(C)OC(=O)NCCCC(=O)N1CCc2ccccc21 +CS(=O)(=O)N1CCc2cc(C(=O)NCc3ccccc3F)ccc21 +COC(=O)NCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CSc1ccc(NC(=O)NCc2ncoc2C)cc1Cl +CCC(C)NC(=O)Cn1c(CNC(C)=O)nc2ccccc21 +COC(=O)c1cccc(Oc2ccc(N)cc2C)c1 +O=C(NCCN1CCOCC1)c1ccc(S(=O)(=O)C(F)F)cc1 +O=C(Nc1cccs1)N1CCC(C(=O)N2CCCC2)CC1 +COc1ccc(CN2CCC(CN3CCOCC3)C2)cc1 +O=C(NCC(=O)N1CCCCCC1)c1ccc(N2CCCC2=O)cc1 +Cc1nc2c(C#N)cnn2c(C)c1CCC(=O)OCc1ccccn1 +COc1ccc(CCNC(=O)COc2ccc(C)cc2)cc1 +CC(C)CC(O)c1ccc2c(c1)C(C)(C)C(=O)N2C +COc1ccc(CN(C)S(=O)(=O)c2ccc(C)cc2)cc1F +CCc1noc(C)c1CN1CCN(CCOC)C(=O)C1 +O=C(CCCc1cccs1)Nc1ccccc1-n1cnnn1 +Cc1cc(C)cc(NC(=O)CCc2c(C)nn(C)c2C)c1 +CCCNc1cc(C)nc2nc(Cc3ccccc3)nn12 +COCCN1CCN(C(=O)NCC(C)c2cccc(C)c2)CC1=O +Cc1cc(NC(=O)CS(=O)(=O)c2nccn2C)no1 +Cc1cccc2c(NCc3ccc(-n4ccnc4)nc3)c(C#N)cnc12 +C#CCNC(=O)NC(Cn1cnc2ccccc21)c1ccc(F)cc1 +OCC(Nc1cc(-c2ccccc2)nc2ccnn12)c1ccccc1 +O=S(=O)(Cc1ccc(F)c(Br)c1)c1ccccn1 +N#Cc1ccccc1NC(=O)CCCC(O)c1ccccc1 +CCCn1c(CN2CCN(C(=O)CC)CC2)nc2ccccc21 +O=C(CCc1nc(-c2ccco2)no1)Nc1cccc2cnccc12 +O=c1[nH]c2ccccc2c(=O)n1-c1ccc(Cl)c(Cl)c1 +COc1ccc(C)cc1NC(=O)C1CC(=O)OC12CCCCC2 +Cn1ncc2c(NCc3cc(F)ccc3Br)ncnc21 +COc1ccc(OC)c2c1cc(C(=O)NCC1CCOCC1)n2C +C=CCC(=O)N1CCOc2c(O)cc(-c3cccnc3)cc2C1 +Cc1ccn2cc(C(=O)Nc3ccccc3OC(F)F)nc2c1 +O=S(=O)(c1cc(C(F)(F)F)ccc1Cl)N1CCC(O)CC1 +CCc1nc(C)c(C(C)OC(=O)c2cccc(NC(C)=O)c2)s1 +COc1ccc(C(=O)CSc2nnc(C)n2C)cc1 +CSc1nc(C)cc(C(=O)N2CCN(S(C)(=O)=O)CC2)n1 +CNC(=O)c1csc(-c2ccc(C(F)(F)F)cc2)n1 +CCCNC(=O)N1CCCCCC1c1ccncc1 +Cc1cscc1C(=O)Nc1ccccc1OC1CCOC1 +CCOCCC(=O)Nc1sc(C)c(C)c1C(N)=O +Cc1cn(C)nc1C(=O)Nc1nnc(-c2ccc(Cl)cc2)o1 +COc1ccc(C2CCc3nc(C(=O)NC(C)(C)C)cn3C2)cc1 +NC(=O)c1csc(CNC(CC(F)(F)F)c2ccc(F)cc2)c1 +Cc1ccsc1CN(C)C(=O)c1cccc(C)c1C +Cc1nc(NC(C)c2cc(C)oc2C)c2cnn(C)c2n1 +FC(F)Sc1ccccc1NCCN1CCOCC1 +CC1CC(NC(=O)c2ccc(F)cc2O)CC(C)O1 +CC(c1cccnc1)N(C)C(=O)NC1CCC2(CC1)OCCO2 +CCOC(=O)c1cc2ccsc2n1CC(=O)NC1CCCC1 +C=CCNc1nc(C(=O)OC2CC(C)OC2=O)cs1 +CCN(C(=O)c1cc(F)ccc1C#CCO)C1CC1 +CCOCc1ccccc1CNC(=O)C1CCCO1 +O=C(CNC(=O)c1ccccc1)Nc1cccc2c1CCCC2 +Cc1c(C(C)NCc2ccco2)nnn1-c1ccc(Cl)cc1 +Cc1cc(NC(=O)CSc2nc(N)cc(N)n2)on1 +COc1cccc(CN2CCC(c3nnc(C)o3)C2)c1 +CC(Cc1nc2ccccc2s1)N1CCC(CN2CCOCC2)C1 +NC(=O)c1ccc(F)c(COc2ccccc2N)c1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2ccccc2O)n1 +N#Cc1ccc(C(=O)NCc2noc(Cc3ccccc3)n2)cc1 +COc1cc(C#N)cc(Cl)c1OCC(=O)N(C)Cc1ccccc1 +COc1cccc(SCc2noc(-c3ccsc3)n2)c1 +CCc1onc(C)c1NC(=O)Cc1cccc(Br)c1 +CNC(=O)COc1ccc(OC(=O)c2cn(C)nc2C(C)(C)C)cc1 +COc1ccc(-c2nc(C(=O)Nc3ncc(C)s3)cs2)cc1 +N#CC1(C(=O)NCc2cn3cc(Br)ccc3n2)CCCC1 +COC(=O)c1[nH]c(C)c(CN(C)C(=O)c2ccc(C(C)C)cc2)c1C +COc1cc2nc(-c3ccccc3)oc2cc1OC +Cc1csc(N2CCN(c3nnnn3-c3ccccc3)CC2)n1 +COC(=O)CS(=O)(=O)c1ccc2c(c1)S(=O)(=O)N=CN2 +O=C(NCCCc1ccccc1F)c1cnc(C2CC2)nc1 +CC(C)(C)n1cc(Nc2ccc3nnnn3n2)cn1 +COc1ccc(C(=O)CCC(=O)NC(C)(C)C)cc1C(C)C +CCOC(=O)c1cncc(C(N)C(=O)OCC)c1 +CN(C(=O)c1cccc(Cl)c1Cl)c1ccccn1 +Cc1cc2c(c(=O)[nH]1)C(=O)OC2=Cc1ccc(Cl)c(Cl)c1 +CC1CN(C(=O)CCc2cn3ccccc3n2)CC1(C)O +Cc1ncc(CNC(=O)N(C)CCc2ccc(F)cc2)s1 +Cc1onc(C(=O)Nc2cc(F)ccc2F)c1C +Cn1c(Sc2ncccn2)nnc1-c1ccc(F)cc1 +COc1cccc(S(=O)(=O)N2CCOCC2)c1 +Cc1csc(C(N)c2ccccc2Br)n1 +COCC1CCN(C(=O)c2nc(N3CCCC3)nc3c2CCCC3)C1 +CNC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)o1 +CCCNc1ncnc(Nc2ccc(F)cc2)c1N +O=S(=O)(Cc1ccccc1F)Nc1ccccc1F +CC1CC1C(=O)OCc1nnc(-c2ccccc2)o1 +CCCn1ncc(-c2ccccc2OC)c(C(C)=O)c1=O +O=c1c2nnc3c(-c4ccc(F)cc4)cnn3c2ncn1CCCO +COCc1ccc(CNc2cnn(CC(F)F)c2)o1 +O=S(=O)(NCc1nnc2ccccn12)c1ccc2c(c1)CCC2 +O=C(c1ccccc1O)N1CCN(c2nccs2)CC1 +CC(=O)c1cccc(NC(=O)C(C)n2c(=O)cc(C)c3ccccc32)c1 +Cc1ncsc1C(=O)C(C#N)c1nc(C(C)C)cs1 +COc1cccc(CN(C)C(=O)C(C)Oc2cccnc2)c1 +CC1CC1CNC(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +O=C(CO)N1CCN(Cc2cc(Cl)cc3c2OCOC3)CC1 +O=C(Nc1ccc(N2CCOCC2)cn1)c1ccccc1OC(F)F +NS(=O)(=O)CCCC(=O)N1CCOC(c2ccc(F)cc2)C1 +Cc1ccc(S(=O)(=O)N2CCCCC2)cc1C(N)=O +CCOCC1CCCN(C(=O)Nc2nnc(CC)s2)C1 +N#CCCN(CCC(F)(F)F)CC1CC=CCC1 +O=C(CCOc1cccc(Cl)c1Cl)N1CCN(CCO)CC1 +CC(C)C(=O)Nc1ccc(C(=O)N(C)Cc2cccc(C#N)c2)cc1 +O=S(=O)(Cc1ccon1)N(Cc1ccccc1F)C1CC1 +CNc1nc(Cn2ccccc2=O)nc2sccc12 +Cc1ccsc1C(=O)Nc1sc2c(c1C(=O)NC1CC1)CCC2 +Cc1ccncc1NC(=O)NC(c1ncccc1C)C(C)C +COc1ccc(C(=O)COC2CCCCC2)cc1F +O=C(N1CCCCCC1)N1CCN(c2ccc(F)cc2)CC1 +CC(OC(=O)c1ccc(Cl)c(N)c1)C(=O)Nc1ccccc1F +Cc1cc(NCc2noc(C3CCCC3)n2)n2nc(C)cc2n1 +O=C1CC(C(=O)N2CCCC2Cn2cccn2)CN1CC(F)(F)F +COc1cccc(NC(=O)Cn2ccc(=O)c3cccc(F)c32)c1 +CCCOc1nccnc1N1CCC(NC(=O)c2ccco2)C1 +O=C(c1cccc(O)c1)N1CCCN(c2ccc(F)cc2)CC1 +CN(C)C(=O)c1ccc2c(-c3nccs3)noc2c1 +COC(=O)CCCC(=O)N1CCc2cccc(F)c2C1 +Cc1nn(C)c2ncc(NC(=O)N(C)C(C)c3ccccn3)cc12 +O=C(Cn1ccnc1-c1ccccc1)N1CCC2(CCCO2)CC1 +Cn1nc(C(=O)Nc2ccc(C(=O)NC3CC3)cc2)ccc1=O +CN(CCCc1ccccc1)C(=O)Cn1cnc(N)n1 +CN(C)C(=O)c1cc(=O)[nH]c2c(Cl)cccc12 +COc1nc2ccccc2nc1CCC(=O)Nc1ccccc1 +NS(=O)(=O)c1nc(C(F)(F)F)ccc1OC1CC1 +Nc1ccc2nc(N(CCO)Cc3ccccc3)sc2c1 +CCNC(=O)C1CC(=O)N(c2ccccc2OC)C1 +COc1ccc(NC(=O)NCC(=O)NC2CC2)c(Cl)c1 +Cc1cnc(C(=O)NCC(=O)Nc2cc(Cl)ccc2Cl)cn1 +O=C(c1cn(Cc2ccccc2)nn1)N1CC=C(c2ccccc2)CC1 +Cc1cc(N2CCC(C)CC2)nc(-n2nc(C)cc2C)n1 +CCc1cc(C(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)no1 +CCC(C)N(Cc1ccccc1F)C(=O)c1ccc[nH]c1=O +O=C(NCCCn1nnc2ccccc21)c1cccc2nccnc12 +CCCn1nccc1C(=O)Nc1ccc(Cl)cc1F +Cc1ccc(NC(=O)c2ccccn2)cc1S(=O)(=O)N(C)C +Cc1ccc(NC(=O)Cn2cnc3ccccc32)cc1F +NC(=O)N1CCCN(C(=O)Nc2cc(Cl)ccc2Cl)CC1 +COc1c(C)cnc(CNC(=O)NCc2ccco2)c1C +CN(CCOCC1CC1)C(=O)c1cccc(C(F)(F)F)c1 +CC(=O)c1cccc(NCc2cn3c(C)cc(C)nc3n2)c1 +COCCN1C(=O)C(=O)c2ccc(Br)cc21 +CC(=O)Nc1ccc2[nH]c(C(=O)NCc3ccco3)cc2c1 +COCCOc1cccc(C(=O)N2CCCC2C(=O)NC2CC2)c1 +Cc1cc(C(=O)Nc2nnc(CCSc3ccccc3)o2)on1 +CC(C)COc1cccc(CNC(=O)NCC2CCCO2)c1 +O=C(NCCO)NCc1ccnc(OCC(F)(F)F)c1 +O=C(CCCCO)Nc1cccc(C(F)(F)F)c1 +COc1ncccc1CNCc1csc(C(C)C)n1 +O=C(NC1CCc2nnc(-c3ccccc3)n2C1)C1(O)CCCCC1 +COc1ccc(CC(=O)Nc2cc3c(oc2=O)CCCC3=O)cc1 +Cc1noc(C2CCCN(C(=O)C3CC(=O)N(CC(C)C)C3)C2)n1 +CCn1cnnc1CNC(=O)N1CCC(OCc2ccccc2)CC1 +CCOC(=O)c1ccc(NC(=O)c2ccc[nH]2)c(O)c1 +O=C(Cn1ccnc1)NCCc1ccc(-n2cccn2)cc1 +O=C(CCc1ccco1)Nc1cccc(Br)c1 +COc1ccc(-c2cc(CSc3nncn3N)on2)cc1 +CCCS(=O)(=O)c1ccc(NCCC2=CCCCC2)nn1 +CCn1c(C2CCCN(C(=O)c3cnc(C)cn3)C2)nn(C)c1=O +COc1cc(OC)c(NC(=O)c2ccc(O)c(Cl)c2)cc1F +CCc1ccccc1NC(=O)CC1OC(=O)c2ccccc21 +CC(C)NC(=O)CN1CCN(c2ccc3c(c2)OCO3)C1=O +O=C(Nc1ccc2cn[nH]c2c1)c1cc(C2CC2)on1 +CCC(NC(=O)c1cccc(-c2ccoc2)c1)c1noc(C)n1 +Cc1ccc(=O)n(CC(=O)N2CCN(c3ccc(F)cc3)CC2)n1 +Cc1n[nH]c2c1c(=O)n(-c1ccccc1)c1ccccc21 +CC(C)CNC(=O)Cc1csc(-c2ccc3c(c2)OCO3)n1 +COc1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1N +Cc1cc(C(=O)Nc2cccc(-c3nc4ccccc4[nH]3)c2)nn1C +CNC(=O)NC1CCN(C(=O)c2cccc(F)c2)C1 +Fc1ccc(NCc2ccn(C3CCCC3)n2)cc1 +O=c1[nH]nc(Cc2ccccc2Br)[nH]1 +CCCNC(=O)CN(C)C(=O)c1ccc2cc(OC)ccc2c1 +Cc1cccc(C(=O)NC(C(=O)NC2CCC(O)CC2)C(C)C)c1 +Cc1csc(CN(C)C(=O)c2ccncc2F)n1 +CC(C)(C)NC(=O)N1CC(c2nc(-c3ccccn3)no2)C1 +CCN(CCC(=O)OC)C(=O)c1c(C)[nH]c2ccccc12 +CC(C)(c1nnc2n1CCCCC2)n1cc(N)cn1 +CCC(C)C(=O)Nc1cccc(CNC(=O)C(C)C)c1 +CC(C)C1(C)Nc2cc(F)ccc2N(CCCC#N)C1=O +CCOC(=O)CC(C)CNC(=O)c1cc(C)nc2c1cnn2C +Cn1cc(-c2nc(CSc3cccs3)cs2)cn1 +CC1(C)OC2OC(C(O)CO)C(OC(=O)c3ccccc3)C2O1 +Cc1ccc(C(=O)N2CCC3(CCCN(c4ncccn4)C3)C2)cn1 +COc1ccc(CNC(=O)NCc2ccnc(-n3cccn3)c2)cc1 +O=C(Nc1cccc(F)c1)c1cccc2cccnc12 +CN1C(=O)CCc2cc(NC(=O)C3CC4C=CC3C4)ccc21 +CC(=O)c1ccc(NC(=O)Nc2ncn(Cc3cccc(C)c3)n2)cc1 +CC(C)c1ncc(C(=O)NC2CCCCC2)c(N)n1 +Cc1ccccc1N1CCN(C(=O)c2sccc2C)CC1=O +COC(=O)c1ccc(NC(=O)Cc2ccccc2N)cc1 +COc1ccccc1OCC(=O)NCC#CCOc1ccccc1C +CC1CN(C(=O)NCc2ccc(Cn3cccn3)cc2)CCO1 +N#Cc1ccc(COC(=O)C2CC(=O)N(CCc3ccccc3)C2)cc1 +CCCNC(=O)NCc1cccnc1-n1ccnc1 +Cc1ccc(C(=O)NCc2cccc(Oc3ccccc3)c2)c(=O)[nH]1 +COc1ccccc1C#CCNC(=O)c1ccc(=O)[nH]c1 +O=C(Cc1ccc2c(c1)CCCC2)NCCc1nccs1 +Cc1nccn1-c1ncccc1NC(=O)COc1ccc(F)cc1 +CN(C)C(=O)CCc1ccc2nc(-c3ccccc3)[nH]c2c1 +CC(C)(C)NC(=O)c1ccccc1NC(=O)Cn1ccccc1=O +CCS(=O)(=O)N1CCOC2CCC1C2Oc1ncccc1F +Cc1ccc(C(=O)OCC(=O)NCc2ccccc2F)c(O)c1 +Oc1ccc(CC2NCCc3ccc4c(c32)OCCO4)cc1 +N#Cc1ccc(C(=O)Nc2c[nH]cc(Br)c2=O)cc1 +O=C(CCC(=O)c1ccc(F)c(F)c1)Oc1ccc2cn[nH]c2c1 +Cc1[nH]c(C(=O)Nc2ccc3nncn3c2)c(C)c1C(=O)OC(C)C +O=C(CCO)N1CCN(C(=O)c2c(F)cccc2Cl)CC1 +Cn1nnnc1SCCOc1ccc(Cl)cc1Cl +CCOCCCNC(=O)c1ccc(C(C)(C)C)cc1 +COCCOc1ccc(-c2nc3scc(N)n3n2)cc1 +CCC(CO)(CO)NC(=O)Nc1nc2ccccc2s1 +O=C1CCC(C(=O)Nc2cccc(C(=O)OCc3ccccc3)c2)N1 +COc1ccccc1CCNC(=O)C1CCn2c(nc3ccccc32)C1 +O=C(Cc1ccc(Cl)cc1Cl)NCc1cscn1 +Cc1ccc(-c2cncc(C(=O)NC3CC3)c2)cc1 +CNC(=O)NCC(=O)N1CCOC(C)(c2ccccc2)C1 +Cc1sc2nc(SCCCO)n(C3CCCC3)c(=O)c2c1C +COc1ccc(CNC(=O)CNC(C)=O)c(OC)c1 +Cc1nccc(NC(=O)c2ccc(-n3cnnc3)cc2)c1Cl +Cc1nc(CC(=O)NC(C)c2cccc(C(F)(F)F)c2)cs1 +COc1ccc(F)cc1NC(=O)N1C(C)CCC1C +COCCNc1nc(-c2cccc(Cl)c2)nnc1C +O=C(Nc1ccc2c(c1)OCO2)c1ccc(Cn2ccnc2)cc1 +CCn1cc(COc2ccc(Cl)cc2N)cn1 +Cc1ccc(C)c(N(C(=O)c2ccc(=O)n(C)c2)C(C)C)c1 +CN(C)C(=O)C1CC=CCC1C(=O)Nc1ccccc1 +Brc1cccc2c1CCNC2C1CCCO1 +Cn1ncc2c(NCc3ccc(OCCO)cc3)ncnc21 +CC(C)N(C(=O)C(C)S(=O)(=O)c1ccccc1F)C(C)C +COc1cc(C(=O)Nc2cccnc2N(C)C)ccc1OC(F)F +COc1ccccc1OCC1CCCN(S(C)(=O)=O)C1 +CCCNC(=O)c1cccc(C(=O)NC(C)C2CCCO2)c1 +NC(=O)c1cccc(NC(=O)NCc2ccccn2)c1 +CNc1ccc(S(=O)(=O)c2ccc(NC)cc2)cc1 +COc1ccc(CCNC(=O)c2ccc3[nH]c(C)nc3c2)cc1OC +CCn1c(SCC(=O)OC)nnc1-c1ccnn1C +O=C(c1cc(C2CC2)[nH]n1)N1CCC(c2ccccc2)CC1 +Cc1ccc(C#N)cc1C(=O)NCc1ccccc1 +O=C(c1ccccc1)N1CCN(CC(=O)N2CCc3ccccc32)CC1 +O=C(Nc1ccncc1)c1cc(F)c(F)c(F)c1 +O=C(c1ccc(=O)[nH]c1)N1CC(c2nc(-c3cccs3)no2)C1 +CC(c1ccccn1)N(C)C(=O)Nc1ccc(F)c(F)c1F +Cc1ccc(CNC(=O)Cn2ncc3c2c(C)nn3C(C)C)o1 +Cc1ccn2c(=NC(=O)c3cnn(-c4ccccc4C)c3)[nH]nc2c1 +COc1cccc(COC(C)C(=O)Nc2cc(C#N)ccc2Cl)c1 +COc1ccc(N)cc1CNC(=O)Nc1cccc(Cl)c1 +NC(=O)C1CN(c2ncnc3c2oc2ccccc23)CCO1 +Cc1ccc2nc(C)cc(C(=O)NCc3nc(C)cc(C)n3)c2c1 +CC1CCCCN1C(=O)c1onc(-c2ccccc2)c1N +COc1ccc(NC(=O)c2cccn(Cc3ccc(C)cc3)c2=O)cc1 +CCCc1cc(C(=O)Nc2cc(OC)c(Cl)cc2OC)no1 +CC(C)COc1cccc(-c2ccc(N)c(=O)[nH]2)c1 +CCn1cc(C(=O)Nc2cc(C(=O)OC)cc(F)c2C)cn1 +CC(C(=O)Nc1ccc(OC(F)F)c(Cl)c1)n1cncn1 +Cn1cccc1C(=O)NCC1OCC2CCN(C(N)=O)CC21 +OC(CSc1ncnc2nc[nH]c12)c1ccc(Cl)cc1 +Cc1nn(Cc2nc(-c3cccs3)no2)c(C)c1Br +CC(C)CNC(=O)NCc1cc(F)ccc1Br +CCN(CC(=O)OC)C(=O)c1ccc(C#N)c(C)n1 +CC(=O)N1CCCc2cc(NC(=O)C3(C)CCCC3)ccc21 +COC(=O)C(C)n1c(-c2ccccc2)nc2cccnc21 +CN(C)C(=O)COc1ccccc1Cc1ccccc1 +CC(=O)c1cccc(NC(=O)c2cc(-c3cccnc3)[nH]n2)c1 +Cc1nc(N2CCC(C)CC2)ncc1C(=O)NC1CCCCC1 +CC1CCN(Cc2nccn2C(F)F)c2ccccc21 +CCn1nc(C)cc1NC(=O)c1cc2c(ccc3ccccc32)oc1=O +COC(=O)N(C)CCCNC(=O)c1cccc(OC)c1O +CCC(C)n1c(C)cn2c3c(=O)n(CCOC)c(=O)n(C)c3nc12 +OC1(c2ccc(F)cc2)CCC2(CC1)OCCO2 +CC(C)(CO)NS(=O)(=O)Cc1ccc(F)cc1 +Nc1nccnc1N1CCNC(c2ccccc2)C1 +Cc1nnc(SCc2cccc(Br)c2)o1 +Cc1csc(S(=O)(=O)CC(=O)N(C)c2ccccc2)n1 +N#Cc1cc(-c2ccc3c(c2)OCCO3)n(-c2ncccn2)n1 +O=C(CSc1ncccn1)Nc1cccc(Br)c1 +O=C(OCc1nnc(-c2cccs2)o1)c1cc2ccccc2[nH]1 +O=S(=O)(NCCc1ccc(OC(F)(F)F)cc1)c1cccnc1 +O=C(NC1CC1)C1CCN(C(=O)c2ccc(-c3ccccc3)cc2)CC1 +CCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(OC)cc1OC +Cc1noc2ncc(C(=O)NCc3cccc(OCC(F)F)c3)cc12 +CS(=O)(=O)N1CCCCC1C(=O)NCc1cccnc1 +Nc1nc(COC(=O)c2ccccc2)nc(Nc2ccc(F)cc2)n1 +CCCCN(CCO)C(=O)NCc1nnc2n1CCCCC2 +CC(OCC1CCCO1)C(=O)Nc1nnc(-c2ccccn2)s1 +CC(C)c1cc(NC(=O)c2cc(Br)cn2C)on1 +CC1CN(C(=O)c2cc(-c3cccs3)n[nH]2)c2ccccc21 +CC(C)CCNS(=O)(=O)c1ccc(F)c(F)c1F +Cc1nc(C(=O)Nc2cn[nH]c2)nn1-c1ccccc1C(C)C +CCOC(=O)CC(C)CNC(=O)c1cc2c([nH]c1=O)CCCC2 +O=C(Nc1ccc2nc[nH]c(=O)c2c1)c1ccccn1 +O=C(CSc1nnc(-c2ccc(Cl)cc2)o1)Nc1cn[nH]c1 +CCN(CC)C(=O)NCC(=O)N(C)CCc1ccccn1 +COc1ccc(CCc2nnc3c(N)cc(C)cn23)cc1OC +CN1CC2(CCN(C(=O)c3ccc(CCC(C)(C)O)cc3)C2)OC1=O +CCN1CCSc2ccc(C(=O)NCCCN3CCCC3=O)cc21 +COC(=O)c1cc(CN2CCN(c3ccccc3O)CC2)c(C)s1 +Cc1cc(C(=O)CC#N)c(C)n1-c1c(C)n(C)n(-c2ccccc2)c1=O +COc1cccc(NC(=O)c2ccc(NC(=O)c3ccco3)cc2)c1 +Cc1ccnc(NC(=O)CCNS(=O)(=O)c2ccc(C)c(C)c2)c1 +CCCn1cc(NCc2c(C)nn(C)c2OC)cn1 +CC(NC(=O)c1ccc(N)cc1)c1ccccc1F +CC(Sc1nnc(N)n1C)C(=O)NCCc1cccs1 +CC(=O)Nc1ccc(NS(=O)(=O)c2cn(C)nc2C)cc1 +CC(C)c1cc(C(=O)NCCCc2nc3ccc(F)cc3[nH]2)no1 +COc1ccc(-c2nnc(SCCC(N)=O)o2)cc1OC +COc1cccc(C(=O)NCC2(C)CCCC2)c1F +Cc1cc2nc(NCCS(N)(=O)=O)c3ccccc3n2n1 +COC(=O)c1ccc(S(=O)(=O)NC2COc3ccccc32)o1 +CC1CN(C(=O)CCS(=O)(=O)c2ccccc2)CC(C)O1 +CCc1cccc(C)c1NC(=O)c1ccc(=O)[nH]c1 +O=C(CC1(O)CCCCC1)NCc1ccnc(OCC(F)(F)F)c1 +O=C(NC1CCCNC1=O)c1csc(-c2ccco2)n1 +COc1cc(C)c(Cl)cc1-c1cc(C)nc(N)n1 +O=C(NCCCN1CCOCC1)NC1(c2ccccc2F)CC1 +O=C(C(c1ccccc1)n1cnnn1)N1CCN(c2ccccc2)CC1 +CC(C)c1noc(CCCC(=O)N2CCCC2c2ccc[nH]2)n1 +CCCOc1ncnc(NCc2ccc(OC)cc2)c1N +CCOC(CC)C(=O)NCc1cccc2ccccc12 +COc1cc(CNc2cccnc2)cc(OC)c1OC +Nc1ccc(-c2n[nH]c(-c3ccc(F)cc3)n2)cc1 +O=C(c1cc(-c2ccco2)cs1)N1CCOCC1 +OCCN1CCN(c2ncc(Br)cn2)CC1 +Cc1ccc2[nH]nc(C(=O)NCC(C)N3CCOCC3)c2c1 +C=CCn1c(C)nnc1SCC(O)c1ccc(F)c(F)c1 +CCCCC(=O)NCCN1CCN(C(=O)c2cccs2)CC1 +CCc1ccc(C(=O)Nc2ccc(N)cc2Cl)cc1 +Nc1cc(NC(=O)c2cscn2)c(F)cc1F +Cc1nnsc1C(=O)NCC(O)c1ccc(C(C)C)cc1 +Brc1cccc(OCCNc2ncnc3[nH]cnc23)c1 +Cc1ccc(NC(=O)NCc2ccncc2)c(Br)c1 +CCOC(=O)c1csc(NC(=O)C(C)Sc2ccccc2)n1 +CCOCC1CCCN(C(=O)c2cc3c([nH]c2=O)CCCC3)C1 +COc1ccc(C)cc1NCc1ccc(OC)c(OC)c1 +CC(C)N(CCC#N)C(=O)CCC1CCCCC1 +C=CCn1cnnc1SCc1ccccc1C#N +CN(C)C(=O)c1cc(NC(=O)C2CC3C=CC2C3)ccc1Cl +COc1cccc2c1OC1(C)CC2NC(=O)N1Cc1ccccc1 +COC(=O)c1ccc(CN(C)CC(=O)NC2(C#N)CCCCC2)cc1 +C#CCNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1 +FC(F)(F)c1cnc(-c2cc(-c3ccn[nH]3)on2)c(Cl)c1 +Cc1csc(NC(=O)CCC(=O)c2ccccc2)n1 +O=C(c1ccc(Cn2nc3ccccn3c2=O)cc1)N1CCCC1 +COC(=O)c1ccc(CN2CCN(C(=O)N3CCOCC3)CC2)cc1 +Cc1cc(NC(=O)c2ccc(OCc3cn4ccccc4n3)cc2)[nH]n1 +C=CCN1CCN(C(=O)COc2ccc(OC)cc2)c2cccnc21 +O=C(NCCc1cnn(-c2ccccc2)c1)Nc1ccc2c(c1)COC2 +COCCNC(=O)c1cccc(OCC(F)F)n1 +Cc1n[nH]c(C)c1NC(=O)Nc1ccc(F)c(-n2cccc2)c1 +O=C(NCc1noc(C2(c3ccccc3F)CC2)n1)c1ccccc1 +CC(C)Oc1ccccc1CNC(=O)C1CCC(=O)N1 +Cc1noc(C)c1CN(C)S(=O)(=O)N1CCCC1 +NC(=O)CC1CCN(C(=O)Cn2ncc3ccccc3c2=O)CC1 +COc1cc(C)c(S(=O)(=O)c2cnc(N)nc2)cc1C +CC1Sc2ccc(NCC(N)=O)cc2NC1=O +CC(C)(C)NC(=O)c1cc(-c2cccnc2)ccc1F +CCNC(=O)NC1CCC(OC(=O)c2ccccc2)CC1 +NC(=O)Nc1ccc(CNC(=O)NCc2ccncc2)cc1 +Cc1cc(C2CCCN2C(=O)c2cc(C(C)C)no2)on1 +COCCN(C)S(=O)(=O)c1c(F)cc(N)cc1F +Cc1nsc(NC(=O)CC2C=CCC2)c1Cl +CCN(CC)C(=O)CSc1nnc2c(n1)[nH]c1ccc(F)cc12 +Cc1cc(Cl)cnc1NC(=O)c1ccc(F)cc1 +Cc1cccc2c(=O)n(CC(=O)Nc3cccc4cccnc34)cnc12 +Nc1nc(NC(=O)c2cccs2)nn1-c1ccccc1 +CN(C)c1cccc(C(=O)N(CC(F)(F)F)c2ccccn2)c1 +FC(F)n1c(SCc2nc(C3CC3)no2)nc2ccccc21 +CCN(Cc1ccccc1NC(=O)Nc1ccc(OC)cc1)C(C)=O +CCN1CCN(C(=O)c2nnc3nc(C(F)(F)F)nn3c2C)CC1 +COCCN(Cc1ccccc1)S(=O)(=O)c1cccc(F)c1 +CC(c1nc(C2CC2)no1)N1CCCC(c2cc(C(N)=O)[nH]n2)C1 +Cc1ccc(NC(=O)Nc2ccccc2)c(OCC(=O)N(C)C)c1 +Nc1cnnc(-c2ccc(C3CCCCC3)cc2)n1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)NCC(C)C)cc1 +CC(C)OCCCNC(=O)c1nc2ncc(Br)cn2n1 +CCOC(=O)C1CCC=CC1n1nnc2ccccc21 +O=C(CC1(O)C(=O)Nc2ccccc21)c1cc2ccccc2o1 +CCNc1nnc(SCC(=O)Nc2ccc(Cl)cc2)s1 +COc1ccc(-c2nc3cc(C)cc(N)c3o2)cc1OC +CC(C)C(=O)N1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1ccc(C(=O)OC)cc1 +Cn1cncc1C1NCCc2c(F)ccc(C(F)(F)F)c21 +O=C(c1cc(F)c(F)cc1Cl)N1CCc2ccccc2C1 +CCOC(=O)c1ccccc1NC(=O)c1ccc(N2CCCC2)nn1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)Nc1cccc2c1CCCC2 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)CCc1ccsc1 +O=C(NCc1cccs1)c1csc2ccccc12 +CC(NCc1ccc(C#N)cc1F)c1ccc(S(C)=O)cc1 +CC(=O)c1ccc(S(=O)(=O)NCc2cscn2)cc1 +CN(CCCc1cnn(C)c1)C(=O)Nc1cccc2[nH]nnc12 +CC(C)(C)C(=O)CSc1nnc(C2COc3ccccc3O2)o1 +Cc1ccc(S(=O)(=O)NCCOCC(C)C)cc1F +C#CCOc1ccc(C(=O)NCc2ccc(Cl)cc2)cc1 +CCOc1cccc(NC(=O)NC(C)(C)c2nc(C)c(C)s2)c1 +Nc1nc2cc(F)c(F)cc2n1Cc1ccccc1 +Clc1ccc2ccn(Cc3nc(-c4ccncc4)no3)c2c1 +CN(CC(=O)NCc1ccccc1)S(=O)(=O)c1ccc(C#N)cc1 +Nc1c(NCc2ccc(Cl)cc2)ncnc1NCc1cccnc1 +Cc1cccc2nc(C(=O)OCc3cc(F)cc4c3OCOC4)cn12 +CC1(C)CC(=O)Nc2ccc(S(=O)(=O)NCC3CCCO3)cc21 +Cc1ccccc1CN1CCN(C(=O)c2cccc(Cl)c2)CC1 +Cc1noc(C)c1S(=O)(=O)N(C)C1(C#N)CCN(C)CC1 +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)NCC(F)(F)F +Cn1nc(N)c2c(N3CCc4ccccc4C3)ncnc21 +Cn1c(C(=O)NCC(=O)Nc2cccc(C(N)=O)c2)cc2occc21 +Cc1cc2nc(C(=O)Nc3ccccc3F)c(=O)n(C)c2cc1C +CCN(Cc1ccccc1)C(=O)c1c(C)oc2ncn(C)c(=O)c12 +COCCNC(C(=O)OC)c1ccc(F)c(Br)c1 +COc1cccc(OC2(C(N)=O)CCCCC2)c1OC +Cc1ncc(CN2CCCC(c3nncn3C)C2)n1-c1ccccc1 +COCCN1C(=O)c2n[nH]c(C)c2C1c1ccc(Cl)cc1Cl +COc1cc(C#N)ccc1C1NCCc2c(F)cccc21 +CN(CCC#N)S(=O)(=O)NCc1cc(-c2ccccc2)on1 +Cc1ncsc1C(=O)N1CCc2nc(N(C)C)ncc2C1 +Cc1cc(Cl)c(Cl)cc1S(=O)(=O)NC(C)C +COc1ccc(C)cc1-c1cc(NC2CC2)nc(C)n1 +C=CCn1c(SCC(=O)OC)nc2ccccc21 +Cc1ccc2nc(CNc3ccccc3F)cc(=O)n2c1 +Cc1cc(C(=O)N2CCNC(=O)C2)c2ccc(F)cc2n1 +O=C(CC1CC(=O)Oc2ccccc21)Nc1nccs1 +CC(=O)NCc1ccc(-c2noc(-c3ccc(C)cc3C)n2)s1 +CC(c1ccccc1)N(CC1CC1)C(=O)Nc1cn[nH]c1 +Cc1cc2c(s1)NC(=O)CN=C2c1ccc(Cl)cc1 +Cc1cc(C(=O)NCc2cccc(F)c2)nc(N2CCCC2)n1 +CCOc1ccccc1NC(=O)c1csc(C)n1 +CCOCCC(=O)Nc1ccc(Br)cc1 +CC(C)COc1cncc(N2CCN(C(=O)c3ccoc3)CC2)n1 +Cc1nc(C)n(-c2ccccc2NC(=O)c2ccc(=O)n(C)c2)n1 +CCOc1ccc(CNC(=O)c2ccc(O)c(Cl)c2)cc1OC +COc1c(C2CCCN2C(=O)c2ccoc2)c(C)nn1C +Nc1cc(NC(=O)CCOCCO)ccc1Cl +Cc1ccccc1CNC(=O)c1ccc(OCC(F)F)nc1 +CS(=O)(=O)NCc1n[nH]c2c1CCN(C(=O)c1csnn1)C2 +O=C(c1ccccc1)c1ccc(OCC(O)CO)cc1 +CC(C#N)Cn1c(-c2ccc(N)cc2)nc2cc(F)c(F)cc21 +Cc1ccc(NC(=O)Cn2nnc(-c3ccc(C(N)=O)cc3)n2)cc1 +COc1cc2c(cc1OC)C1(CCCC1)CNC2CO +CC1CC1CNC(=O)NCc1nc2ccccc2s1 +COc1ccc(OC)c2c1C(=O)NCC2C1CCCC1 +CCC(=O)Nc1cccc(C(=O)OCc2nc3ccccc3[nH]2)c1 +Cc1cc(NCc2cccc(C(F)(F)F)c2)no1 +COc1ccc(S(=O)(=O)NCC2CCCO2)cc1NC(C)=O +CCn1cc(C(=O)NC2CCN(C(=O)CC(C)C)CC2)cn1 +COC(=O)COc1cc(C)nc(-c2cccc(Cl)c2)n1 +Cc1nn(C)c(C)c1CCC(=O)N1Cc2ccccc2-c2ccccc21 +Cc1ccc(C)c(C(=O)C2CCCN2S(C)(=O)=O)c1 +Cn1nncc1CN1CCN(CC(=O)N2CCc3ccccc32)CC1 +CCN(CC)C(=O)CCC(=O)Nc1ccnn1C(C)C +CCn1c(=O)c2c(nc(N)n2CC)n(CCCOC)c1=O +COC(=O)c1occc1CN1CCc2cc(S(N)(=O)=O)ccc21 +CC(NC(=O)Nc1ccc2c(c1)OCC(=O)N2)c1ccc(C#N)cc1 +O=C(c1ccc(F)cc1)N1CCC2(CC(=O)N(c3ccccc3)C2)C1 +COc1cc2c(cc1CNC(=O)Cn1cccnc1=O)CCC2 +Cn1cc(C(N)=O)cc1C(=O)Nc1ccccc1Oc1ccccc1 +O=S(=O)(Nc1ccccc1F)c1cccc2cccnc12 +CC1CC(N2CCCC(C(=O)Nc3ccc(Cl)cn3)C2)C(=O)O1 +COCc1cc(NC(=O)N2CC=C(c3ccccc3F)CC2)ncn1 +CC(C)(C)c1cc(NC(=O)CN(CCO)c2ccccc2)on1 +Nc1ccnn1Cc1ccccc1Br +Cc1nn(C)c(C)c1C1CCCN1C(=O)Cc1ccc2c(c1)CCO2 +CNC(=O)c1cc(C)ccc1NC(=O)c1cscn1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)Cc1ccc[nH]1 +CCCc1ccc(C(=O)Cn2ccsc2=O)cc1 +CC1CCN(C(=O)CSc2cc(N3CCCCC3)ncn2)CC1 +C#CCn1c(CNC(=O)c2ccccc2C)nc2ccccc21 +CCC(OC)C(=O)Nc1cc(OC)c(OC)cc1Br +CC(C)c1ccc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)cc1 +O=C(NCCc1cccc(F)c1)c1n[nH]c2ccccc12 +Cc1ccccc1OCC(=O)Nc1ccc(C(=O)N(C)C)cc1 +Cc1cccc(C)c1NC(=O)CN1CCN(C(=O)C2CCCO2)CC1 +COc1ccc(-c2ccc(SCC#N)nn2)cc1 +CCN(CC)C(=O)c1cccc2c(OC)ccc(OC)c12 +Cc1cc(CN(C)c2nnc(C(C)C)s2)no1 +O=C(Nc1ccc(Br)cn1)c1coc(-c2ccccc2)n1 +CN(C(=O)CS(=O)(=O)c1ccc(F)c(F)c1)C1CCCCC1 +CNS(=O)(=O)c1cccc(C(=O)NC2(C)Cc3ccccc3C2)c1 +CNC(=O)c1ccc(NC(=O)NCc2ccccc2OC)cc1Cl +COc1ccc(C2NC(=O)c3ccccc3N2)cc1OC(F)F +Cc1cccc(CN2CCN3C(=O)N(Cc4ccccn4)CC3C2)n1 +CCOc1ccc(NC(=O)c2nc3nc(C)cc(C)n3n2)c(C)c1 +Nc1c(O)n[nH]c1-c1ccccc1Br +Cc1cc(C)c(NC(=O)CCn2c(=O)oc3ccccc32)c(C)n1 +Cc1ccc(C(=O)N2CCN(Cc3cscn3)CC2)s1 +CC(=O)NC1CCN(C(=O)NCCc2cc(C)cc(C)c2)CC1 +O=C(NCCN1CCOCC1)c1ccc2ccccc2n1 +Cc1cc2c(cc1NC(=O)Cc1cccnc1)OCO2 +COCN1C(=O)C(c2ccccc2)Oc2ccc(CO)cc21 +CCC(C)Oc1ccc(NC(=O)CN(C)S(C)(=O)=O)cc1 +Cn1c(CCNC(=O)c2ccc(O)c(Cl)c2)nc2ccccc21 +O=C(Cn1ccc(-c2cccc(-c3cnccn3)c2)n1)N1CCCCC1 +COC(=O)NC(C(=O)NCc1nc(C)sc1C)C(C)C +COc1ccccc1CNc1ccc(N2CCCC2=O)cc1 +CC(NC(=O)NC(C)C1CCCO1)c1ccc(Cl)cc1 +COc1ccc(-c2cnc(Cn3nc4ccccn4c3=O)o2)cc1 +CCC(NC(=O)CN(C)c1ccc(C#N)cn1)C(C)C +CC(C)(C)c1csc(C2CCCCN2C(=O)C2COCCO2)n1 +COCCOc1ccc(NC(=O)NC(C)c2ccc(C)cc2)cn1 +Cc1cc(NC(=O)Nc2ccccc2)n(C2CCCC2)n1 +CNc1nc(Nc2ccc(F)cc2)c2nccnc2n1 +Cc1ccc(Sc2ncnc(N3CCOCC3)c2N)cc1 +CCC1CCC(CNC(=O)C2CCN(S(=O)(=O)CC)CC2)CC1 +N#Cc1c(-c2ccc3c(c2)CCC(=O)N3)c[nH]c1N +Cc1cc(C(=O)N2CCCCCC2)ccc1N(C)S(C)(=O)=O +O=C(NCCCO)c1cc(-c2ccco2)n(-c2ccc(Cl)cc2)n1 +CCc1nnsc1C(=O)N1CCCSc2ccccc21 +CCc1ccc(NC(=O)C(C)N2CCOc3ccc(N)cc32)cc1 +O=C(NCc1cc2ccccc2[nH]1)C(O)c1ccccc1Cl +CCC(CC)NC(=O)NCCN(C)c1ccccc1 +CC1CCCC(CNC(=O)N2CCN(C(=O)c3ccco3)CC2)C1 +O=C(Nc1n[nH]c2cc(O)ccc12)c1ccccc1 +CC(C)C(=O)N1CCC(C(=O)Nc2cc(F)ccc2F)CC1 +CC(C)(C)C(=O)c1nnc2sc3ccccc3n12 +CC(C)(C)OC(=O)N1CCCC1C(=O)NCCc1nncn1C1CC1 +Cc1cnc(C(=O)NCc2cccc(C(N)=O)c2)cn1 +Cc1[nH]c(=O)c(C(=O)NC2CCC3CCCC32)c(C)c1C +O=C(NCCOCc1ccccc1)c1ccccc1Br +CCOC(=O)CCC1NCCc2ccc(NC(C)=O)cc21 +Cc1ccc(CNc2ncccc2Cl)cc1F +Cc1ccn(-c2ccc(NC(=O)c3ccc4c(c3)OCCO4)cc2)n1 +O=C(c1ccc(-n2ccc(-c3cccnc3)n2)cc1)C1CC1 +CCN(CC)C(=O)CCN1C(=O)C(C)(C)c2ccccc21 +CCc1cccc(OCC(=O)Nc2nc(-c3ccccn3)cs2)c1 +O=C(C(Cc1ccccc1)n1cnnn1)N1CCCCCC1 +COc1ccc(C(=O)NC(C)c2ccccn2)cc1Br +Cc1sc2nc(SCC(=O)NCCCO)nc(N)c2c1C +CC(C)c1ccccc1OCCC(=O)N1CCC(O)CC1 +Cc1ccccc1OCCn1cnc2c(cnn2-c2ccccc2)c1=O +N#CCC(CC#N)C(c1ccccc1)c1ccccc1 +Cc1csc(CNc2ccccc2C(=O)N(C)C)n1 +Cn1ccnc1C(NC(=O)Cc1ccsc1)c1ccc(F)cc1 +CCn1c(C)nnc1SCCNC(=O)c1cc(C)c(C)[nH]c1=O +COc1cccc(NC(=O)C(C)n2ccc(N)n2)c1 +CCn1c(SCC(=O)C2=NC=CC2)nnc1-c1ccncc1 +O=C(c1ccno1)N1CCc2ncnc(-c3ccncc3)c2CC1 +COc1ccc(S(=O)(=O)NC2CCCC(C)C2C)cc1OC +Cc1cc(C(=O)N(CC(F)(F)F)C2CC2)ccc1N +Cc1ccc(N2CCN(CC(=O)NCc3ccsc3)C2=O)cc1 +CC(C)NC(=O)c1ccccc1S(=O)(=O)N1CCCCC1 +Cc1n[nH]c(C(=O)Nc2cccc(OCC#N)c2)c1Br +CC=CCCNC(=O)NCc1ccc(C)cc1N(C)C +CCOC(=O)CCCS(=O)(=O)N1CCCc2cc(C)ccc21 +CC(=O)N(C)c1cccc(NC(=O)c2ccncc2)c1 +O=C(NCc1ccncc1)C1(c2cccs2)CCCCC1 +CC(C)(C)OC(=O)NCC1NCCc2c(O)cc(O)cc21 +COc1cccc(OC)c1-c1cnn(C)c(=O)c1C#N +Cc1ccsc1CNC(=O)c1ccc2c(c1)OCC(=O)N2 +Cc1cccc(NC(=O)CNC(=O)c2cncn2-c2ccccc2)c1C +COc1ccc(OC)c(CNC(=O)c2cnc3snnc3c2)c1 +CCC(OC(=O)CCc1nc(C)no1)c1ccc(F)cc1F +CCS(=O)(=O)N1CCCc2ccc(NC(=O)C(C)C)cc21 +CC1=NC(C(F)(F)F)(C(F)(F)F)NC(=O)N1Cc1ccco1 +CCC(=O)Nc1cccc(C(=O)NCc2nc3ccc(F)cc3[nH]2)c1 +CCC1COC2(CCCN(C(=O)c3ccccn3)C2)C1 +CC(C)c1nc(CC(=O)N2CCN(c3ccc(O)cc3)CC2)cs1 +Cc1noc(C(C)N2CCN(C(=O)c3ccccc3Cl)CC2)n1 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1cc(=O)[nH]c2ccccc12 +Cc1nc(C(F)(F)F)ccc1C(=O)N(C)Cc1cccc(F)c1 +O=C(Nc1nc(-c2ccccc2Cl)cs1)C1CCOCC1 +CCSc1nc(=O)c2c(n1C)NC(=O)CC2c1ccc(Cl)cc1 +CN(C)C(=O)Cn1cc(C(=O)NCCOc2ccccc2)nn1 +CN(C)c1nc2cc(NC(=O)CCNC(=O)c3ccco3)ccc2o1 +COc1ccc(CNC(=O)NCC#Cc2ccc(F)cc2)cc1 +CCCn1cc(Br)cc1C(=O)NCC1COCCO1 +Cc1cc(NC(=O)NC(C)C)ccc1Oc1cccnc1 +Cc1ccc(S(=O)(=O)Nc2ccccc2O)cc1C +O=C(NCC1(c2ccccc2)CC1)c1cnc(-c2ccccc2)nc1 +Cc1nnc(NCc2cc(Cl)ccc2C)s1 +COc1ccc(NC(=O)NCc2ccccc2F)cc1 +CC(C)CC(=O)NCc1ccc(Cn2ccnc2)cc1 +Cc1cccn2c(=O)nc(SCC(=O)N(C)c3ccccc3)nc12 +Cc1nsc(NC(=O)N2CCN(Cc3cccc(F)c3)C(=O)C2)n1 +COc1ccccc1CN1CCN(S(=O)(=O)c2ccccc2)CC1 +Cn1cc(CNC(=O)c2ccc3c(c2)CCC3)cn1 +CCCC(NC(N)=O)C(=O)N1CCC(c2ccc(F)cc2)C1 +CCOC(=O)CCCn1nnc(-c2ccc(Br)cc2)n1 +CCCN(C)C(=O)c1ccc(OC)c(S(=O)(=O)N(C)C)c1 +CC(=O)N1CCN(C2CCCc3ccccc32)CC1 +COc1ccc(OC)c(C(O)CNC(=O)Nc2ccc(OC)nc2)c1 +CNC(=O)c1cccc(OCC(=O)N2CCCC2c2cccs2)c1 +Cc1c(C(=O)NCCC(=O)N2CCCC2)nc2ccc(Cl)cn12 +CC(C)(C)c1cc(NC(=O)CN2CCOCC2C2CC2)on1 +c1ccc(CNc2cc(-c3ccncc3)nc(-c3cccnc3)n2)cc1 +CCOC(=O)CC(C)CNC(=O)Nc1cccc(Br)c1 +CC(C)(C)OC(=O)NCCC(O)c1ccccc1 +c1ccc2sc(CCc3nc(C4CC4)n[nH]3)nc2c1 +COC(=O)N1CCC(NC(=O)NCc2cccs2)CC1 +CC(NC(=O)C1(n2cnnn2)CCCCC1)c1nc2ccccc2[nH]1 +C#CCN(CC#C)Cc1c(C)nn(Cc2ccccc2)c1C +COc1ccc(CN2CCC(c3nc(C)cc(=O)[nH]3)C2)cc1 +N#CC(Cc1cccnc1)C(=O)Nc1ccccc1Cl +COC(=O)CCCCNC(=O)Nc1ccc(C)cc1F +Cn1ccc(C2CCCCCN2C(=O)Cc2cccs2)n1 +Nc1cccc2c1OCC(=O)N2Cc1ccccc1Cl +CCOc1ccccc1NC(=O)CC(C#N)c1ccccc1F +COc1ccccc1NC(=O)C1CCN(C(=O)c2ccccc2)CC1 +O=C(CSc1ccncc1)NCc1cccc(F)c1 +CN(C)C(=O)Cn1nc(-c2cccc(-n3cccc3)c2)oc1=O +Cc1nc(CC(=O)OCC(=O)NC2CCOc3ccccc32)cs1 +COC(=O)c1cc(-c2cc(C(F)(F)F)ccc2O)on1 +CN1C(=O)C(O)(CC(=O)c2ccc(F)cc2)c2cc(Cl)ccc21 +NC(=O)c1sc2nncc(-c3cccnc3)c2c1N +O=C(CC1(O)CCCCC1)NCc1cccc(OCC(F)(F)F)c1 +COC(=O)C(C)Sc1nc(C)cc(C)c1C#N +O=C1COc2cc(O)ccc2N1Cc1ccc(Cl)cc1 +CNc1nn2c(=O)c(Cc3cccc(OC)c3OC)nnc2s1 +O=C(NCCc1cccc(F)c1)c1ccc(-n2cccc2)cc1 +O=C(c1ccccc1F)N1CCC(Nc2ncnc3c2CCC3)CC1 +CCC(C)N(Cc1ccncc1)C(=O)c1ccc(C(=O)OC)cc1 +CCOc1ccc(F)c(C(=O)Nc2cccc(COC)c2)c1F +O=C(c1ccc(COc2ccc(F)cc2)o1)N1CCOCC1 +Cc1cc(=O)n(CC(=O)Nc2ccc(Cl)cc2)c(N2CCCC2)n1 +CC(C)CN1Cc2cc(Cl)ccc2OCC1=O +Cc1nc(C)c(C(=O)NCC#Cc2ccc(C(N)=O)cc2)s1 +O=c1[nH]c(-c2cnccn2)nc2scc(-c3ccccc3Cl)c12 +O=C(NCc1cc2ccccc2[nH]1)c1cc(-c2ccco2)on1 +Cc1cc(C(=O)N2CCCC3(CC(CN4CCOCC4)CO3)C2)no1 +CCC1Cc2cc(N)ccc2N(C(=O)OC(C)(C)C)C1 +CC(C)(CO)C1NCCc2cc(Cl)c(Cl)cc21 +C=CCNC(=O)N1CCc2nc(NC(=O)C3CC3)sc2C1 +O=C(NCCc1cn2ccccc2n1)c1cn2cccnc2n1 +C#CCSc1nnc(C2CC2)n1-c1cccc(Cl)c1 +O=C(NCc1n[nH]c(=O)c2ccccc12)c1cc(=O)c2ccccc2o1 +CCOCc1nc(N2CCC(O)CC2)ncc1C(=O)OCC +CC(C)n1c(=O)[nH]c2cc(C(=O)NC3CCCC3)ccc2c1=O +CCOc1cccc(C(C)NC(=O)C(C)Sc2ccccn2)c1 +COCC1CN(C(=O)c2cnc(C)cn2)Cc2ncnn2C1 +CC(C)(C)NC(=O)c1cccc(NC(=O)NC(C)(CO)C2CC2)c1 +CC(c1ccccc1F)N(C)C(=O)NCCN1CCOCC1 +CSc1ncccc1C(=O)NCC(O)c1cn(C)c2ccccc12 +COC(=O)C(C)n1c(-c2cccc(F)c2)nc2cccnc21 +O=C(c1ccc(S(=O)(=O)NCc2cccnc2)cc1)C1CC1 +C=CCN(CC=C)C(=O)C(C)N1CCN(C(=O)c2ccco2)CC1 +CC(=O)Nc1nc(CC(=O)NCCN2CCOCC2)cs1 +CNc1snnc1Cn1ccnc1-c1cccs1 +Cn1nnc2c(N3CC(C(=O)N4CCc5ccccc5C4)C3)ncnc21 +c1nc(N2CCc3sccc3C2)c2sccc2n1 +CCN(CC(=O)NC(C)C)C(=O)Nc1ccccc1 +Cc1nc(C2CCCN(C(=O)c3cnn4ccccc34)C2)cc(=O)[nH]1 +CCN1CC(CN(C)C(=O)C(C)n2cncn2)Oc2ccccc21 +Cc1ccc(C2COCCN2C(=O)c2ccccc2C)o1 +CC(NCc1ccccc1)C(=O)Nc1ccccc1 +CCOc1ncccc1C(=O)N1CCCC(c2noc(C(C)C)n2)C1 +C=CCNC(=O)c1ccc(OCc2cn3cc(C)ccc3n2)cc1 +COc1ccccc1COc1ccc(C(C)O)cc1 +CCCc1cc(O)nc(SC(C)C(=O)N2CCOCC2)n1 +O=C(Nc1ccccc1-n1cnnn1)c1scnc1C1CC1 +Cn1nccc1CNC(=O)NCc1ccc2c(c1)OCO2 +CC(C)c1nc2cc(NC(=O)C3COc4ccccc4O3)ccc2[nH]1 +Cc1nn(C)c2[nH]nc(NC(=O)c3cc(-c4ccc(F)cc4)on3)c12 +O=C(CCCO)NCCc1ccc(Br)cc1 +CCN(CCC(=O)OC)S(=O)(=O)c1cc(Cl)ccc1C +OCCN(Cc1cccc(F)c1)Cc1cccs1 +O=C(Cc1ccc(Cl)cc1)Nc1ccc(C(=O)NC2CC2)cc1 +CN(C(=O)COc1ccccc1)C1(C#N)CCCCC1 +O=C(NCCOc1ccc(F)cc1F)NCCc1cccnc1 +COc1ccc(C(O)c2ccc(Cl)cc2)cc1OC +Cn1ccnc1Cn1c(CCO)nc2ccc(F)cc21 +O=C(c1ccncc1)N1CCCc2cc(F)cc(F)c21 +CCCCC(=O)NCc1cccc(-c2n[nH]c(C)n2)c1 +CCCc1nc2ccc(OCC(C)O)cc2s1 +O=C(Cn1ccc2ccccc2c1=O)NCCC(=O)NC1CC1 +NC(=O)CC1CCN(C(=O)Cc2ccc3c(c2)CCC3)CC1 +Cc1noc(C)c1C(C)NC(=O)Cc1ccc(Cl)cc1 +CCC(NC(=O)Cn1nc(C)c2ccccc2c1=O)c1ccnn1C +COc1cc(F)c(C(=O)C2CCCCN2)cc1F +C#CCOC(=O)c1ccccc1C(=O)n1nnc2ccccc21 +Cc1noc(C)c1COc1ccc(C(=O)NCC(N)=O)cc1 +COC(=O)c1sc(NC(=O)c2cc(F)ccc2C)nc1C1CC1 +CCCC(NCc1ccc(F)c(C#N)c1)C(=O)OC +CC(Nc1cccc(NC(=O)C2CC2)c1)C(=O)NCc1cccs1 +COC(=O)C(C)NC(=O)C1(c2cccs2)CCCCC1 +Cc1ccc(CNC(=O)N2CCC(C)(CO)CC2)c(N(C)C)c1 +Cc1cccc(C)c1NC(=O)c1coc(NC(=O)c2cccs2)n1 +CCOC(=O)c1cnc(-n2cc(C)cn2)nc1Nc1ccccc1 +CCC1Oc2ccc(N)nc2N(CCCC#N)C1=O +N#Cc1cccc(NCCC(=O)c2cccs2)c1 +CCc1[nH]nc(-c2cc(OC)c(OC)c(OC)c2)c1NC(=O)C1CC1 +Cc1ccc(C)c(OCC(=O)NCC(C)(C)N2CCOCC2)c1 +Cc1nc(-c2ccc(CNS(=O)(=O)N(C)C)cc2)ccc1C(N)=O +O=C(NCc1ccco1)C1(c2ccc(Cl)cc2)CC1 +CC(C)(C)c1ccc(SCC(=O)N2CCC(C(N)=O)C2)cc1 +N#Cc1ccc(OC(=O)COc2ccc3ccc(=O)oc3c2)cc1 +CCOCC1CCN(C(=O)Nc2ccccc2-n2nc(C)nc2C)C1 +Cc1ccc(NC(=O)CSc2nnc(C)o2)c(Cl)c1 +COc1ccc(C)cc1NC(=O)C1Cc2ccccc2CN1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCc1cnn(C)c1C)O2 +CC1CCC(NC(=O)CCc2nc3ccccc3s2)CC1 +O=C(NCCc1ccccn1)C1(c2cccc(Cl)c2)CC1 +Cc1cc(C)n2ncc(C(=O)N3CCOCC3C)c2n1 +CCN(CC)C(=O)Nc1cccc(Cn2nc3ccccn3c2=O)c1 +CC(CNC(=O)N(C)Cc1ccncc1)Sc1ccccc1 +CC(C)c1ccc(-c2cc(CC#N)c(=O)n(C)n2)cc1 +CSc1ccc(COc2ccc(NC(C)=O)cc2)cc1 +CCOc1ncccc1CNC(=O)NCCOC +Cc1cc(C(C)NC(=O)Cc2ccc(Br)cc2)c(C)o1 +CN(Cc1nc2ccccc2s1)C(=O)C1CCOC1 +O=C(CCc1ccccc1F)NCC(O)c1ccco1 +CCCn1c(C)c(C(=O)NC(C)(C)C(=O)OC)c2cc(OC)ccc21 +CCc1nnc2n1CC(NC(=O)Cc1coc3cc(C)ccc13)CC2 +N#Cc1ccc(CSc2nc(C3CC3)n(-c3ccccc3)n2)cc1 +CCCCN(C)C(=O)NCCc1nc(C(C)C)no1 +NC(=O)C1CCN(C(=O)NCc2ccc(Cn3ccnc3)cc2)CC1 +O=C(NCCn1ncccc1=O)C1(c2ccc(Cl)cc2)CCCC1 +Cc1cccc(NCC(=O)Nc2ccc(C(=O)NC(C)C)cc2)c1 +COC(=O)C1(NC(=O)Cn2cccc(C)c2=O)CCCCC1 +O=C1Nc2ccccc2C1Cc1c(F)cccc1Cl +CCN1CCC2(CCCN(C(=O)c3ccc[nH]3)C2)C1=O +COc1ccc(CNC(=O)c2csc(C(=O)NC3CC3)n2)cc1 +CCc1ccc(CC2Oc3ccc(N)cc3N(CCO)C2=O)cc1 +CCOc1cc(C(=O)OC)cc(Br)c1O +O=C1COc2cc(C(=O)NC3CC=CC3)c(Br)cc2N1 +Cc1ccccc1COC1CCN(C(=O)c2ccc3cc[nH]c3c2)CC1 +COC(=O)c1cc(C2CC2)nc2onc(-c3ccc(OC)cc3)c12 +Cc1ccc(NC(=O)CSc2nnc(C)n2-n2cccc2)cc1 +Cc1ccc(C(=O)CCC(=O)N(c2ccccc2)C(C)C)s1 +COCCOc1ccccc1-c1nc(C(=O)N2CCOCC2)cs1 +CCCn1cc(Br)cc1C(=O)Nc1ccc(O)cc1 +Cc1cc(C)n(CCNC(=O)Nc2ccc(C)c(C(C)C)c2)c(=O)n1 +O=C(Cc1cn2ccsc2n1)Nc1ccccc1OC(F)(F)F +COc1ccc(C(C)COC(=O)C2CCNC(=O)C2)cc1 +COC(=O)c1cc(-c2c(C)oc3cc(O)ccc3c2=O)c(C)o1 +CCNc1ncccc1COc1ccc(C#N)cc1 +N#Cc1ccc(N2CC3(CCN(c4nccs4)C3)C2)nc1 +Cc1cc(S(=O)(=O)NCCN2CCOCC2)c(C)s1 +Nc1ccc(C(O)COc2ccc(F)cc2Br)cc1 +O=C(Nc1ccon1)Nc1ccccc1C(F)(F)F +CC(C)Oc1ccc2c(c1)nc(-c1cccc(N)c1)n2C +COCC(C)NC(=O)CCNC(=O)c1ccco1 +CC(C)NC(=O)N1CCC(c2nn(C)c(=O)n2-c2ccccc2)CC1 +COc1c2ccc(C(=O)N3CCCCC3)cc2nn1C +CCn1nc(C(=O)N2CCCCC2)cc1-c1ccc2c(c1)OCO2 +COc1cc(Cn2cnc(C3CCC3)cc2=O)ccc1SC +CCCNS(=O)(=O)c1cc(C(=O)OCC)n(C)c1C +Nc1c(NCc2ccccc2)ncnc1NC1CCCC1 +CCCn1nc(C(=O)Nc2ccc(-n3ccnc3)cc2)ccc1=O +CNC(=O)NCC(=O)N1CCN(C(=O)C2CCCCC2)CC1 +Cc1cc2c(cc3c(=O)n(CC(=O)N4CCC(C)CC4)nc(C)n32)o1 +COc1ccc(Br)cc1C(=O)Cn1cnc(C#N)n1 +O=C(NCCC(=O)N1CCCC1)c1cc2cccn2cn1 +COc1ccc(NC(=O)COc2ccccc2CO)cc1Cl +Cc1cc(C(=O)NCC2COCCO2)c(C)n1C1CC1 +CCCN(CCC)C(=O)C1CC(=O)N(c2ccc(C)cc2)C1 +COc1ccc(C2(Cc3ccc(Cl)cc3)NC(N)=NC2=O)cc1 +CCn1nc(C)c(S(=O)(=O)Nc2ccc(C)c(C)c2)c1C +CC1COCCN1C(=O)C1CCN(c2ccc(C#N)cn2)CC1 +CCCCSc1nnc(-c2ccccc2)c(=O)n1N +CN(C)C(=O)c1ccc(S(=O)(=O)N2CCc3ccccc32)s1 +CN(CC(=O)NC1(C#N)CCCCC1)c1cccc(C#N)c1 +CNC(=O)Cc1noc(-c2cc3ccccc3cc2O)n1 +COC(=O)c1ccc(NC(=O)c2cccc(-c3noc(C)n3)c2)cc1 +CCC(C)NC(=O)CN1C(=O)CCCc2ccccc21 +O=C(Nc1cccc(F)c1)C1CCCN1C(=O)c1ccc(F)cc1 +Cc1ccc(NC(=O)c2ccc(C#N)cc2)c(F)c1 +CC(C(=O)N(C)CCOc1ccccc1)c1cccs1 +COCc1cccc(NC(=O)NCCN(C)c2ccccc2)c1 +CC(NC(=O)CNC(N)=O)c1cccc(OC(F)F)c1 +COc1cccc(Cc2nc(-c3ccc4c(c3)nnn4C)no2)c1 +COc1ccccc1OCC(=O)NC(C)c1cc(C)ccc1C +Cc1cc2nc(NS(=O)(=O)c3ccccc3)[nH]c2cc1C +O=C(NCC(=O)N1CCCC1)c1cccc(-n2cnnn2)c1 +Cc1c[nH]c(=O)n1-c1ccc(C(=O)N2CCCC2c2ccccc2)cc1 +CCN(CCNC(=O)c1ccc(C(N)=O)cc1)c1cccc(C)c1 +C#CCN1C(=O)C(CC)(CC)Oc2cccc(N)c21 +COC(=O)CC(NC(=O)c1ccc(F)cc1)C(=O)OC +COCCCNC(=O)N1CCCCC1c1nc2ccccc2s1 +Cc1ccc(S(=O)(=O)NCc2ncn(C)n2)c(C)c1 +CC1CCC(C(N)=O)CN1c1ccc(C#N)cc1F +COC(=O)C(C)(C)NCc1ccc(F)cc1Cl +CC1(NS(=O)(=O)Cc2cccc(C#N)c2)Cc2ccccc2C1 +COCCN(CCC#N)S(=O)(=O)c1cc(C#N)ccc1C +Cc1ccc(NC(=O)c2ccc(NCc3ccccn3)nc2)cc1 +COC(=O)C(NC(=O)Cc1c(C)noc1C)C(C)C +Cc1cc(C)n(S(=O)(=O)c2cc(C)c(Br)cc2C)n1 +CNc1snc(C)c1C(=O)Nc1ccc(OC)c(OC(F)F)c1 +Cc1ccc2cnn(CC(=O)N3CCC4(CC3)OCCO4)c2c1 +CCN1CC(C(=O)N(C)CCOc2ccccc2F)CC1=O +CC(=O)Nc1ccc(Cl)c(C(=O)N(C)C(C)c2ccon2)c1 +CC(C)(C)Oc1cc(CNC(=O)c2cccc3cc[nH]c23)ccn1 +C=CCN(CC=C)C(=O)c1ccc(NC(=O)c2cc(C)oc2C)cc1 +Cc1ccc(C)c(CC(=O)N(C)C(C)c2ccccn2)c1 +O=C(Nc1nc2c(Br)cccc2s1)C1CCC1 +COc1ccc(OCC(=O)NCCc2ccccc2)cc1 +O=C(NCCC1=CCCCC1)c1ccc(N2CCCC2)nn1 +O=c1cc(-c2ccccc2)c2cc3c(cc2[nH]1)OCO3 +CN(C)C(=O)N1CCN(C(=O)OC(C)(C)C)CC1 +CC(C)(CNC(=O)c1ccc2ccccc2c1O)N1CCOCC1 +CCOC(=O)C(O)Cc1ccc(NC(C)=O)c(F)c1 +O=S(=O)(Nc1ccc(F)c(F)c1)C1CCCCC1 +CC(C)(CNC(=O)Cn1cc(C2CC2)nn1)c1ccncc1 +N#CCCN(CCC#N)Cc1ccn(-c2c(F)cccc2F)n1 +CC(C)NC(=O)c1ccc2c(=O)n(-c3ccccc3)cnc2c1 +O=C(NCC(O)(c1cccs1)C1CC1)Nc1c(F)cccc1F +CC(=O)c1oc2ccc(C3=CC(=O)OC3)cc2c1C +Cc1cc(NC(=O)Cn2ccc3ccc(Cl)cc32)n(CCC#N)n1 +CC(=O)NCC1CCCN(C(=O)NCCSc2ccccc2)C1 +COC(=O)C(NC(=O)C(C)Oc1cccc(C)c1)C(C)C +CN(C)S(=O)(=O)NC1CCOc2c(Cl)cccc21 +CC(NC(=O)Cc1cccs1)C(=O)NC(C)(C)C +O=C(Nc1ccc2[nH]ncc2c1)c1ccc(N2CCCOC2=O)cc1 +CC12CCC(C(=O)Nc3ccccc3-n3cccc3)(CC1=O)C2(C)C +COCCN(Cc1ccsc1)C(=O)Nc1ccc(F)cc1 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+CCOc1c(Cl)cccc1NC(=O)c1ccc(S(N)(=O)=O)o1 +Cc1noc(-c2ccc(N3CCCC(CN4CCCC4=O)C3)nc2)n1 +CCNC(=O)C(C)NC(C)c1cccc(OC)c1 +COC(=O)CNC(=O)C1CCC(NC(=O)CC2CCCCC2)CC1 +COc1ccc(C(O)CNS(=O)(=O)N(C)C)c(OC)c1 +COc1ccc(OCCN(C)C(=O)c2cc(C)sc2C)cc1 +CCOC(=O)Cn1nc(CO)cc1-c1cccs1 +O=c1[nH]nc(SCc2cccc(Br)c2)n1C1CC1 +COc1c(C)cc(C)cc1-c1csc2nc(N)nn12 +O=C(Cc1ccsc1)Nc1ccccc1N1CCOCC1 +CNC(=O)CN(c1ccccc1C)S(=O)(=O)c1cnn(C)c1 +CNc1nc(N2CC(C)C(O)(C3CC3)C2)ncc1F +CN1C(=O)c2cccc3c(S(=O)(=O)N(C)CC(C)(C)O)ccc1c23 +CCn1nnc2cc(C(=O)NCCCCC(C)C)ccc21 +CC(=O)c1ccc(OCC(=O)Nc2ccc3nc(C)oc3c2)cc1 +Cc1cccc(C)c1NC(=O)N1CCOCC1C1CC1 +CC1CCCCC1NC(=O)C(c1ccccc1F)N1CCOCC1 +Cc1ccc2oc(C(=O)Nc3cccnc3N3CCCC3)cc2n1 +N#CCCCOc1cccc(NC(=O)NCCO)c1 +CCn1nc(C(=O)Nc2cccc(C)n2)c(=O)c2ccccc21 +CN(C)C(=O)Cn1ccc(C2CCNc3ccccc32)n1 +O=C(Nc1ccccc1Cl)C1COc2ccccc2O1 +CC(C)c1ccccc1NC(=O)NCCN1CCOCC1 +O=C(c1ccc(-c2cnco2)cc1)N1CCCOC2CCCC21 +Cc1noc(C)c1S(=O)(=O)N(C)c1c(F)cccc1F +COc1ccccc1C(=O)N1CCC(Oc2cccnc2)CC1 +CCC(C)NS(=O)(=O)c1ccc(S(N)(=O)=O)cc1F +CC(C(=O)NCCCn1cncn1)n1cnc2ccccc21 +CCOC(CC)C(=O)Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1 +COc1ccc(CCNC(=O)c2cc[nH]n2)c(OC)c1 +CCc1noc(CC)c1CNC(=O)NCc1ccc(O)c(F)c1 +CCC1CN(Cc2cc(OC)cc(OC)c2)CC(C)O1 +CNC(=O)C1CCCCC1NC(=O)c1cccc(OC)c1F +COc1ccc(C2CCCN2C(=O)NCC2CCCO2)c(OC)c1 +COc1ccccc1C(C)CC(=O)Oc1ccc(-n2cnnn2)cc1 +Cc1nn(-c2ccccc2F)c(C)c1CC(=O)NCC1CCCO1 +O=C(C1CCN(c2cnccn2)CC1)N1CCCc2sccc2C1 +COc1cc(CNC(=O)CCCc2ccccc2)ccn1 +COc1nccnc1CN1CCC(NC(=O)OC(C)(C)C)C1 +COc1cccc(OC(=O)c2cn(C)c(=O)c3ccccc23)c1 +O=C(NCc1ccc(F)cc1)c1cnc2[nH]ccc2c1 +O=C(NCCCOc1ccc(Cl)cc1Cl)c1cc[nH]c(=O)c1 +CCc1nnc(CNC(=O)c2c(C)nc3ccc(C)cn23)s1 +COCCNC(=O)c1nnc(Cc2cccc(F)c2)o1 +CS(=O)(=O)NC1CCN(C(=O)c2cc3cnsc3s2)C1 +CC1CN(c2nc3c(c(=O)[nH]2)CCN(c2ncccn2)C3)CC(C)O1 +CCCc1cc(O)nc(SCC(=O)Nc2cc(C)nn2C)n1 +CCC(C)NC(=O)c1ccc(NC(=O)C(C)C)cc1 +CC1CNC(c2ccccc2)CN1C(=O)C1CCCO1 +CC1(C)COC2(CCN(Cc3cnc4ccccn34)CC2)OC1 +CC(C)NC(=O)Cn1ccc2ccnc(-c3cccs3)c21 +Cc1c(OC(=O)C2CC2)ccc2c(=O)c(Cl)coc12 +CC(C)COC(=O)N1CCC(NCC(=O)NC2CCCCC2)CC1 +CC(C)C(Nc1ccc(=O)n(C)c1)c1cccs1 +COc1ccc(C(=O)Nc2ccc3oc(=O)[nH]c3c2)cc1OC +Cc1cc(F)ccc1CCNC(=O)CNC(=O)CC1CCCC1 +CCN(CCO)C(=O)CCNC(=O)c1ccco1 +CCOC(=O)C1=C(C)C(C(=O)N2CCCCC2C)C(C)=N1 +CN(C)C(=O)c1ccc(CN2CC=C(c3cccs3)CC2)[nH]1 +CCCN(C)S(=O)(=O)c1ccc(C)c2c1CCCN2 +COCc1cc(=O)n(CC(=O)Nc2ccc(OC)c(F)c2)c(N)n1 +Nc1ccc2c(cnn2Cc2ccc(Cl)cc2)c1 +O=C(CNC(=O)Nc1nc(Cc2ccccc2)cs1)NC1CC1 +Cc1ccncc1NC(=O)N1CCN(c2cccs2)CC1 +Cc1cccc(CNC(C(=O)NC2CC2)c2ccccc2)c1 +COc1ccc(COC(=O)c2cccs2)cc1OC +NC(=O)c1cc(NC(=O)NCc2ccc(F)c(Cl)c2)ccc1F +O=C(NCC1CCOC1)c1cc(-c2ccco2)on1 +COc1ccc(C)cc1N(C(C)C(=O)N1CCCC1)S(C)(=O)=O +CC(C(=O)NCC1CCCO1)N1CCCc2ccccc21 +Cc1nnc(-c2ccccc2NC(=O)Cc2cc(F)ccc2F)o1 +Cc1cc(CNC(=O)c2ccc(F)c(C(F)(F)F)c2)no1 +CCn1nc(C#N)cc1-c1ccc(OC)cc1OC +Cn1nc2nc(NCc3ccccn3)nc(-c3ccccc3F)c2c1N +CCn1cc(NC(=O)N(C)Cc2ccccn2)cn1 +O=C(CO)N1CCN(C(=O)CCc2cccc(F)c2F)CC1 +COc1cccc(C(=O)NCC(=O)N2CCc3sccc3C2)c1F +COc1ccc2cc(CNc3c(C)cc(C)cc3C)c(=O)[nH]c2c1 +COc1ccc(CC(C)CNC(=O)c2sc(C)nc2C)cc1 +Cc1noc(C)c1CCC(=O)N1CCN(C(=O)c2ccoc2)CC1 +Nc1cnc(-c2ccc(Br)cc2)nn1 +Cn1nc(COCC2CC2)c2c1CN(C(=O)c1ccnnc1)CC2 +Cc1ccc(NC(=O)CCc2nnc(-c3ccccc3)o2)cc1 +COc1ccc(NC(=O)c2ccccc2NC(=O)c2ccccc2)cn1 +Cc1cccc2[nH]c(C3CCCN(C(=O)c4ccn(C)n4)C3)nc12 +Cc1ccc(S(=O)(=O)Nc2ccc(N)cc2F)cc1C +CCN(CC)S(=O)(=O)CC(=O)Nc1ccc(Cl)c(Cl)c1 +CC(Nc1ccc2nnnn2n1)c1nc2cc(Cl)ccc2[nH]1 +O=C(COC(=O)Cc1ccc(F)cc1)Nc1ccc(F)c(F)c1 +CC1Oc2ccccc2OC1C(=O)Nc1cccnc1 +CC1CN(C(=O)Cn2c(=O)oc3ccccc32)c2ccccc2S1 +COc1cc(-n2cccc(C#N)c2=O)cc(OC)c1OC +CCN(CC(=O)OC)c1ncc(Cl)cc1Cl +CC(=O)c1ccc(OCc2ccccc2)c2c1OCC(=O)N2 +O=c1[nH]ncc(NCc2ccc(Oc3ccc(F)cc3)nc2)c1Cl +Cc1cccc2c(=O)[nH]c(CN(C)C(C)c3ccccc3)nc12 +CS(=O)(=O)c1ccc(C=Cc2ccc(S(C)(=O)=O)cc2)cc1 +Cc1ccc(CNC(=O)NCCN2CCOCC2)cc1 +CCC(C)N(C(=O)C1CN(C(=O)c2cccs2)C1)C(C)CC +Cc1ccc2c(n1)OCCN2Cc1noc(C2CCOCC2)n1 +C=CCOC(=O)c1sc2nc(C3CC3)[nH]c(=O)c2c1C +CC1(C)CN(C(=O)CCc2ccc(Cl)cc2)CCO1 +CS(=O)c1ccc(CN(CCC#N)CC2CC2)cc1 +COCC(=O)N1CCc2c(CNc3ncccn3)n[nH]c2C1 +COc1ccc(OC)c(S(=O)(=O)N(C)c2ccc(F)c(F)c2)c1 +O=C(Nc1cccc(NCC(=O)N2CCCCC2)c1)c1ccccc1 +Cc1nc(C(=O)NC(C)C)c(C)n1C1CCN(S(C)(=O)=O)CC1 +Cc1nnnn1Cc1ccc(-c2nc(C3CCOC3)no2)cc1 +COC(=O)N1CCC(CNC(=O)c2ccc(F)cc2)CC1 +O=S(=O)(NCCN1CCOCC1)N1CCCCCC1 +Cc1nc(SC(C(N)=O)c2ccccc2)c2c(C)c(C)sc2n1 +CC1CCCC(N(C)C(=O)CCNS(=O)(=O)c2cccnc2)C1 +O=C1CC(c2nc(-c3cccs3)no2)CN1Cc1ccc(F)cc1 +CCCCN(CC(F)(F)F)C(=O)c1ccc(F)cc1 +COC(=O)C(C)N(C)Cc1ccc(Cl)c(Cl)c1 +Cc1ccc(C2C(C(=O)NC(C)C)CC(=O)N2C)cc1 +C=CCOc1cccc(NC(=O)c2ccc(OCC)nc2)c1 +O=S(=O)(Cc1ccccc1)NC1CCN(c2nccs2)CC1 +CCCS(=O)(=O)N1CCCCC1C(=O)NCc1ccc(O)cc1 +CC(C)CCOc1cc(C(=O)NC(C)C)ccc1N +CCCN(CCc1ccccn1)S(=O)(=O)c1ccc(F)cc1F +COC(=O)C1CCCC1NC(=O)Nc1ccc(OC(F)F)cc1 +COc1cccc(C(=O)Nc2ccnc3ccccc23)c1 +CCC(C)Nc1ccc(-c2nc(CC(C)C)no2)cn1 +CC1COCC(C)N1Cc1ncccc1C(F)(F)F +NC(=O)c1ccc(Cl)c(NC(=O)c2ccc(F)cc2)c1 +CC1C(OC(=O)CCC(=O)N2CCOCC2)CC2CC1C2(C)C +COc1ccc(Cl)cc1NC(=O)Cn1cnc(C(C)C)cc1=O +COC(=O)NCCCC(=O)Nc1nc2ccc(Cl)cc2s1 +FC(F)(Br)C(F)(Cl)Br +Cn1cc(Nc2cccc(NC(=O)c3ccncc3F)c2)cn1 +CCCC(=O)N1CCC(C(=O)NCc2cccc(C#N)c2)CC1 +CN(C)c1ccc(C(=O)NCCC(O)c2cccc3ccccc23)cc1 +C=CCNC(=O)CN(C)S(=O)(=O)c1ccc(C(C)=O)cc1 +COc1ncccc1CNC(=O)NCc1cc2ccccc2o1 +CC(C)COC(=O)N1CCCC1C(=O)NC1CCCCCC1 +COc1cc(CNC(=O)c2csc(NC(C)=O)n2)ccn1 +Cc1ccc(F)cc1NC(=O)c1cc(C2CC2)nc2c1c(C)nn2C +O=C(Cn1c(=O)sc2ccccc21)Nc1cccc(F)c1 +Cc1cccc(C)c1CN(Cc1ccccc1)S(C)(=O)=O +Cc1cc(S(=O)(=O)NCCCCO)ccc1Cl +COc1ccc(SCC(=O)N2CCc3cc(F)ccc3C2)cc1 +N#Cc1cccc(C(=O)Nc2cc(Cl)c(N)c(Cl)c2)c1 +CCC1(NC(=O)Nc2cncnc2N(C)C)CCC1 +COC(=O)C(c1ccccc1F)N1CCCC2(C1)OCCO2 +FC1(F)CCN(Cc2ccccn2)CC12CCN(c1ccccc1)C2 +CS(=O)(=O)c1ccc(CNC(=O)Nc2cc(F)cc(F)c2)cc1 +CCCN(CC(=O)OC)S(=O)(=O)c1ccc(O)cc1 +Cc1cnc(CCN(C)C(=O)c2cccc(-c3ccoc3)c2)s1 +CC(C)Cn1ncc(C(=O)N(C)c2ccccc2F)c1C1CC1 +C=CCN(CCc1ccccc1)C(=O)NCc1ccnn1C +O=C(CSc1ccc2ccccc2n1)N1CCCCC1 +CC1(C)CCC(CNC(=O)Cn2c(=O)cnc3ccccc32)CC1 +O=C(c1cccs1)N1CCN(c2ccnc(N3CCCC3)n2)CC1 +CN(Cc1ccccn1)C(=O)CCSc1nc2ccccc2s1 +CC(C)c1nc(CCNC(=O)Cc2c(F)cccc2F)cs1 +NS(=O)(=O)c1ccc(NC(=O)c2cccc(-n3cccc3)c2)cc1 +COc1ccc2c(=O)cc(C(=O)NCc3cccnc3)oc2c1 +COc1ccc(NC(=O)NCc2ccncc2)cc1F +O=C(NCCCC1CCCC1)NCc1cccs1 +Cc1ccc(-n2ncc3c(N(CCO)CCO)ncnc32)c(C)c1 +COc1cccc(CNC(=O)c2cc(Cl)c3c(c2)OCO3)c1 +COc1cccc(C(=O)OC(C)C(=O)Nc2cccc(C)c2)c1O +Cc1noc(C)c1CCCNC(=O)Nc1ccc(C(N)=O)c(F)c1 +O=c1c2cc(Cl)cc(Cl)c2nc2cccnn12 +Cn1c(=O)[nH]c(=O)c2cc(C(=O)Nc3ccc(F)cc3F)cnc21 +CN(Cc1cccc(C#N)c1)Cc1cnn(Cc2ccccc2)c1 +Cc1oc(C)c2c(=O)cc(-c3ccc4c(c3)OCO4)cc(O)c12 +CC(=O)c1ccc(S(=O)(=O)N2CCN(C)CC2)cc1 +CC(C)CCNC(=O)CCC(=O)N1CCCCCC1 +NC(=O)C1CCN(C(=O)Nc2ccc(F)cc2)C1 +CCC(=O)c1ccc(S(=O)(=O)NC(C)c2ccccc2)cc1 +Cc1cc(-c2cnc(C)nc2CN(C)C(=O)C2CC2)on1 +Cn1cc(-c2ccnc(NCC3CCCCO3)n2)cn1 +O=C(NCc1cc(-c2ccc(F)cc2)on1)c1ccc[nH]c1=O +CCN(Cc1cccs1)C(=O)Cn1ccc(=O)n(C)c1=O +CC(C)CCN(C(=O)NC(C)c1nnc2ccccn12)C1CC1 +Cc1cc(C(C)NC(=O)NC(C)C(C)C)c(C)s1 +CCNc1ncc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)s1 +Cn1cccc1C(=O)N1CCCCC1c1nc(-c2ccccc2)no1 +CN(C)C(=O)CCNC(=O)c1ccn(-c2ccccc2)n1 +O=C(NCCc1ccccn1)Nc1cccc(SC(F)F)c1 +O=C(NCCn1nc2ccccn2c1=O)c1cnns1 +Cc1cc(NC(=O)CCOc2ccc(F)cc2)n(C)n1 +O=C(Cc1ccc[nH]1)Nc1cccc(-c2nnco2)c1 +Cn1ccc(C(=O)OCc2c(F)cccc2Cl)n1 +CCn1cc(-c2nncn2-c2cccc(C(C)=O)c2)c(C)n1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccc(OC(F)F)cc1 +COc1cc(C#N)ccc1OC(=O)CCCc1cccs1 +COCCCC1CCCN(C(=O)Cc2ccc(O)cc2)C1 +COC(=O)NCC(=O)N1CCCCC1c1ccc(F)cc1 +O=C(Cc1csc(-c2ccco2)n1)NC1CCCCC1 +COc1ccc(-c2nnn(CC(=O)NCc3ccco3)n2)cc1OC +Cc1ccc(C(=O)NCc2ccc(OCC(F)(F)F)nc2)cc1 +N#CCc1nc(-c2ccc3c(c2)CCC(=O)N3)cs1 +O=C(NCCC1CCCCC1)NCc1ccc(-n2cncn2)cc1 +CC=C(C)c1nc(C2(NC(=O)OC(C)(C)C)CCC2)no1 +COC(=O)c1sc(N2CC(C)OC(C)C2)nc1N +COCCNC(=O)c1ccc(S(=O)(=O)N2CCC(C)CC2)cc1 +O=C1CSc2sc3c(=O)n(Cc4ccco4)cnc3c2N1 +COc1ccccc1OCCn1cc(C#N)c2ccccc21 +Cc1cccc(C)c1N(CC(=O)NCc1ccncc1)S(C)(=O)=O +COc1ccnc(N2CCN(c3ccc(C(F)(F)F)cn3)CC2)n1 +CC(C)(C)c1nc(COc2cccc(-n3cnnn3)c2)no1 +COc1c(C)cnc(CN(C)C(=O)c2ccc(F)cc2)c1C +CN(C)c1ccc(-c2nc3ccc(C#N)cn3n2)cc1 +Cc1cc(C(=O)N2CCCC(CO)(CCCc3ccccc3)C2)n[nH]1 +COc1cccc(C(O)CNc2ccccc2C#N)c1 +Cn1cnnc1SCCC(=O)Nc1cccc(Cl)c1 +CCn1cc(C(=O)NC(C)c2cc(OC)c(OC)c(OC)c2)cn1 +O=C(NCCC(O)c1ccco1)C1(c2ccccc2)CCOCC1 +CCc1noc(CN(C)C(=O)Nc2cc(-c3ccccc3)on2)n1 +C#CCN1CCN(CC(=O)Nc2c(C#N)cnn2-c2ccccc2)CC1 +CC(O)(CNC(=O)c1ccc(OCC(F)F)nc1)c1ccccc1 +Cc1ccncc1NC(=O)c1cnn(-c2ccncc2)c1C +CCOC(=O)C(C)Sc1nncn1-c1cccc(Cl)c1 +COC(=O)c1ccccc1NCc1ccc(C#N)cc1 +O=C(Cc1csc(-c2ccco2)n1)N=c1[nH]c2ccccc2[nH]1 +CC(C)COc1cccc(CNC(=O)N2CCOCC2)c1 +COc1cccc(NC(=O)CCSc2nnnn2C)c1 +N#CCn1ccc2c(Cl)c(Cl)ccc2c1=O +Cc1ccn(CCNS(=O)(=O)c2ccc3c(c2)NC(=O)CO3)n1 +Cc1cc(C)nc(-n2nc(C)cc2OC(=O)C2CC2)n1 +O=C(NCCn1ncc2ccccc2c1=O)C1Cc2ccccc2CN1 +O=c1[nH]nc(CN2CCN(Cc3cccc4ccccc34)CC2)[nH]1 +N#Cc1ccc(NC(=O)c2ccc(F)cc2)cc1C#N +Cc1ccc(C(=O)NC(C)c2ccc(C(F)(F)F)cc2)cn1 +CCOC(=O)C1CCCN(C(=O)c2cccc(-c3ccoc3)c2)C1 +CCNC(=O)c1ccc2c(c1)N(Cc1ccc(F)cc1)C(=O)CO2 +CNC(=O)c1cc(C)ccc1NC(=O)CC1=CCCCC1 +Cc1cccc(CCC(=O)N(C(C)C)C2CCOCC2)c1 +N#CC1(C(=O)N2CCc3nnc(Cn4cccn4)n3CC2)CC1 +COc1ccnc(COC(=O)c2sc(C)cc2OC)c1 +CCOc1ccc2c(c1)nc(CO)n2C(C)c1ccccc1 +O=C(c1cncc(Br)c1)N1CCOc2ccc(F)cc21 +CC(O)CNC(=O)c1n[nH]c2c1CN(C(=O)OC(C)(C)C)CC2 +COc1ccc(-c2nc(CCNC(=O)c3cnc(C)cn3)co2)cc1 +CCOC(=O)c1c(C)[nH]c(C(=O)N(C)C2CCCCC2)c1C +COc1ccc(S(=O)(=O)N(C)c2ccc(C)cc2C)cc1OC +O=C(CN1CCN(C(=O)c2cccc(Cl)c2)CC1)N1CCCC1 +c1cncc(CN(Cc2ccco2)Cc2nccs2)c1 +CC(=O)Nc1ccc(O)c(C(=O)Nc2nc3c(s2)CN(C)CC3)c1 +CCOc1ccccc1CNC(=O)N1CCOC(C)(C)C1 +CCN1CCN(c2ccc(NC(=O)CCc3ccccc3)cn2)C1=O +CC(C)CC(=O)NC1(c2cccc(F)c2)CCOCC1 +CN(CC(=O)Nc1ccn(Cc2ccncc2)n1)c1ccc(C#N)cn1 +O=C(Cc1cccs1)Nc1ccc2c(c1)OCCCO2 +CN(C)C(=O)c1cc(=O)c2cc(Cl)ccc2o1 +CC1(C)CN(CCC(N)c2ccccc2F)CCO1 +O=C(NCCCc1cccc(F)c1)c1csnn1 +CCN1CCN(C(=O)c2cc(C)n(Cc3ccccn3)c2C)CC1 +Cc1c(-c2ccccc2)nc2ccccc2c1C(=O)N1CCOCC1 +Cn1nc2nc(NCC3CC3)nc(-c3cccs3)c2c1N +O=C(NCCC(F)(F)F)N1CCC(OCc2ccc(F)cc2)CC1 +CC(Sc1ccccc1N)C(=O)Nc1nccs1 +CN(C)c1cc(C(=O)NC2CCc3c(O)cccc32)ccn1 +CSc1ccc(CNC(=O)CSc2ncn[nH]2)cc1 +CCOC(=O)c1cccc(-c2nc3ccc(N)cc3o2)c1 +CC(CCn1cncn1)NC(=O)N1CCOC2(CCCC2)C1 +O=C(CCc1ccsc1)NC1CCc2c(F)cccc21 +Cc1nc(C(=O)NC(C)c2ccc(C(C)C)cc2)cs1 +Cc1ccc(C)c(C(=O)COc2ccc(C(N)=O)cc2)c1 +Cc1ccc(-c2cc(C(=O)N(C)Cc3n[nH]c4c3CCC4)[nH]n2)s1 +CC(C)Sc1ccccc1C(=O)NCc1ccc2c(c1)OCCO2 +CC(C)(C)OC(=O)N1CCNCC1c1ccc(F)cc1 +Cc1cc(C)c(C(=O)NCc2cccc(OCC(C)C)c2)c(=O)[nH]1 +COc1ccc(CNC(=O)NC(C)C(C)C)cn1 +CC(O)CC1COCCN1C(=O)NCCCc1cccc(F)c1 +NC(=O)C1CCN(C(=O)COc2ccc(F)cc2)c2ccccc21 +Cc1nn(CCC(=O)NCCCN2CCOCC2)c2ccccc12 +CCOC(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +COC(=O)CNC(=O)N1CCCC1c1ccccc1C +Cc1cc(CNc2ccc(C)c(S(=O)(=O)NC3CC3)c2C)no1 +CC(=O)c1cccc(S(=O)(=O)N2CCNC(=O)C2)c1 +O=C(CC1COCCN1C(=O)c1ccn2ccnc2c1)c1ccco1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)N1CCc2ccccc2C1 +COc1cccc(NC(=O)c2ccc(CN3CCOCC3)cc2)c1 +Cn1nc2c(c1NC(=O)c1cc(Cl)c3c(c1)OCCCO3)CCC2 +O=C(Nc1ccc2nc(C3CC3)[nH]c2c1)c1ccncc1 +O=C(COC(=O)c1ccc(Cl)cc1)Nc1ccc2c(c1)OCO2 +COc1ccc(CNS(=O)(=O)c2ccc3c(c2)N(C)CCO3)cc1 +COCCN(C(=O)NC1CCOCC1)c1ccc(OC)c(OC)c1 +Cc1cccc(OCC(=O)N2CCC3(CC2)OCCCO3)c1 +COCc1cnc(Nc2nc3ccccc3o2)nc1C(=O)OC +Cc1cc(NCc2ccc(CS(N)(=O)=O)cc2)nc(C)n1 +NC(=O)NCCCCC(=O)Nc1ccc2c(c1)OCCO2 +Cc1c(C(=O)Nc2ccccc2Cl)nnn1-c1ccccc1 +Cc1nn(CCO)c(C)c1CNC(C)Cc1ccc2ccccc2c1 +O=c1c2[nH]c3ccc(Cl)cc3c2ncn1Cc1cccnc1 +CN(Cc1c(F)cccc1Cl)S(=O)(=O)N1CCCC1(C)C +COc1cccc(-c2cc(C(=O)NCc3cc(F)cc(F)c3)n[nH]2)c1 +CCOc1ccccc1C(CC(=O)N1CCC(C)CC1C)NC(C)=O +NC(=O)CN(C(=O)c1cccc(F)c1)C1CCCC1 +COC(=O)c1c[nH]nc1-c1ccc(Br)cc1 +CCOc1ccc2c(c1)CN(c1ccc(C#N)cn1)CC2 +O=C(NCCCn1cncn1)c1ccc(Br)cc1F +CC(C)NC(=O)c1ccc2c(c1)nnn2Cc1ccc(F)cc1 +CCN(CC1CCOC1)C(=O)Nc1cccnc1-n1cccn1 +N#Cc1cc(S(N)(=O)=O)ccc1N1CCN(c2ccccc2)CC1 +O=C(NCCC(=O)N1CCc2nocc2C1)C1CCC1 +N#Cc1ccccc1NC(=O)C(O)c1ccccc1 +O=C1CCCc2nc(NC(=O)C3CC=CC3)sc21 +CC1=C(C(=O)NCC(C)(C)c2ccncc2)CCCO1 +O=S(=O)(c1cccc(Cl)c1F)N1CCC(CO)CC1 +CCNC(=O)CSc1nc2sc(C)c(C)c2c(=O)n1CC +O=C(Nc1ccc(-n2ccnc2)nc1)c1cnc2ccccc2n1 +Cc1cc(C)n(CC(=O)Nc2ccc(F)c(F)c2)c(=O)c1C(N)=O +CCOC(=O)c1cnn2c3c(cnc12)C(=O)CC(c1cccc(C)c1)C3 +COc1cc(S(=O)(=O)NCCc2ccccc2)ccc1Cl +COCCCNC(=O)CNc1cc(Cl)ccc1C +Cc1cc(NC(=O)c2ccc3ncccc3c2)ccc1C(=O)N(C)C +Cn1c(C(=O)NCC(=O)NC(C)(C)C)cc2occc21 +CC(=O)c1ccc(-n2cnnc2Cc2c[nH]c3ccccc23)cc1 +COCCN(C(=O)c1ccn(-c2ccc(OC)cc2)n1)C1CCCC1 +CC(C)n1cc(NCc2ccc(OCC(F)F)cc2)cn1 +CC(C)OCc1ccc(CNC(=O)c2ccoc2)cc1 +CC(C)Sc1nnc(NC(=O)C2CCCC2)s1 +CC1CCCC(NC(=O)CS(=O)(=O)c2ccccn2)C1C +CC(O)CNC(=O)C1CCCN1C(=O)OC(C)(C)C +OCc1ccccc1OCCOCC(F)(F)F +CC(C)NC(=O)CCn1ncc2c(Cl)cccc21 +CC1(C)Oc2ccccc2OC1(O)c1ccc2ccccc2n1 +CC1CC1c1ccc(CN(C(=O)Nc2nncs2)C2CC2)o1 +C=CCNC(=O)C(C)Sc1nnc(N2CCCCC2)n1C1CC1 +COc1ccccc1CC(=O)Nc1ccc(N2CCOCC2)cn1 +Cc1c(Cl)c(C(=O)NC2C3CC4CC(C3)CC2C4)nn1C +COc1cccc(-c2ccc(-c3nc(C4CCOC4)no3)o2)c1 +O=C(NCCCO)Nc1ccc(Oc2ccc(F)cc2)nc1 +Cc1cc(C(=O)N2CCC(C(C)N3CCOCC3)CC2)ccc1O +NS(=O)(=O)c1ccc(-c2csc(Nc3ccccc3)n2)cc1 +O=C(Cn1ccc2ccccc21)N(Cc1cnc2ccccn12)C1CC1 +Cc1c(NCc2cccc(C#N)c2)cccc1C(=O)N1CCOCC1 +Cc1cc(NC(=O)NCc2ncc[nH]2)ccc1C(=O)OC(C)(C)C +COC(=O)C(NC(=O)C1CCC1)c1ccccc1C(F)(F)F +CC1COCCN1C(=O)Nc1cnn(CC(N)=O)c1 +O=C1NC(Cc2nc(C3CC3)n[nH]2)c2ccccc21 +CN(Cc1cccc(F)c1)C(=O)Nc1ccc2c(c1)COC2 +N#CC(NS(=O)(=O)CCCc1ccccc1)c1ccccc1 +CCOc1ccc(F)c(C(=O)NC(COC)C2CC2)c1F +Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CC(C)C +Cc1ccc(-n2nc(-c3ccccc3)[nH]c2=O)cc1 +CC1CC1C(=O)NCCNc1cccc(F)c1C#N +COc1cccc(CCNC(=O)N2CCN(c3ncccn3)CC2)c1 +Cc1nn(C)cc1-c1ccnc(N2CCc3sccc3C2)n1 +Cc1nnc(NCCOCCC(C)C)c(C#N)c1C +O=C(CSc1nnc(-c2ccc(Cl)cc2)[nH]1)N1CCCCC1 +Nc1nonc1-c1noc(-c2ccc(Cl)c(Cl)c2)n1 +Brc1ccc2c(c1)C(c1ncco1)CN2 +Cc1ccn(-c2ccccc2CNC(=O)Nc2ccc3c(c2)COC3)n1 +O=C(NCC(=O)N1CCCCC1)c1cccc(OCC(F)F)n1 +Cc1ccc(C(=O)NC(C)C(=O)NC2CCCC2)s1 +CC(CO)(CO)Nc1ncnc2cc(F)c(F)cc12 +CCC(C)(NC(=O)c1cc(C2CC2)on1)c1nc(C)cs1 +N#CC(NC(=O)c1ccc2c(c1)OCO2)c1ccccc1Cl +Cc1ccc(CCC(=O)N2CCOCC2c2ncon2)c(C)c1 +Cn1nc(C(=O)NC2CCCCC2)c2c1-c1ccccc1OC2 +Cc1nc(NC(=O)NCC2CC(=O)N(C(C)(C)C)C2)nn1C(C)C +CCC(C)(C)NC(=O)c1cn(CCOC)c2ccccc12 +Cc1noc(C)c1CNC(=O)c1ccc(-c2ccco2)[nH]c1=O +Cc1ccc(NC(=O)C(C)C)cc1NCC(=O)NC(C)(C#N)C(C)C +Cc1nn(C)c(C)c1CC(=O)OCCn1c(=O)oc2ccccc21 +Cc1ccc(Cl)cc1S(=O)(=O)NC1CCCC(O)C1 +CNC(=O)NCC(=O)NC(CC1CCCCC1)c1ccccc1 +Cc1sc2ncn(CC(=O)NCc3ccccc3)c(=O)c2c1C +CCn1c(C)c(CS(=O)(=O)c2ccccc2)[nH]c1=O +CCNc1cc(C(C)C)nc(Cc2nc(C)cs2)n1 +CCC(=O)NC1CCCN(C(C)C(=O)Nc2ncccn2)C1 +CCOCCn1c(=O)[nH]c2cc(C(=O)N3CCC(CO)CC3)ccc21 +CC(C)(C#N)NC(=O)c1ccc(COc2ccccc2)cc1 +Cc1cc(NC(=O)C(C)OC(=O)c2ccc3c(c2)OCC(=O)N3)on1 +CC(C)n1cnc(S(=O)(=O)Nc2nc3ccccc3[nH]2)c1 +CN1CCN(C(=O)CCC(=O)c2ccc3c(c2)CCC3)CC1 +COC(=O)c1cccc(CCNC(=O)N2CCC(CO)C2)c1 +CCOc1cc(C#N)ccc1OCC(=O)N1CCc2ccccc21 +COC(=O)NC(C)(C)C(=O)N(C)Cc1ccc(SC(F)F)cc1 +O=C(Cc1cccs1)N1CCc2ccc(=O)n(CC3CC3)c2CC1 +COc1cc(C(C)C)ccc1C(O)Cn1cc(N)cn1 +COCCN(Cc1ccc(OC)cc1)c1nc2c(s1)c(C)nn2C +CC(C)(C)OC(=O)N1CC2Nc3cscc3C2C1 +O=C(CSc1ncn[nH]1)NC1CCOc2ccccc21 +CCN(CC)S(=O)(=O)c1ccc2c(c1)n(CC)c(=O)n2CC +O=C(OCC1CCCCO1)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CC(=O)Nc1nnc(COc2ccc(Cl)cc2C)s1 +CCOc1ncccc1CNC(=O)NCc1ccccc1Cl +COCCN1CCCC2(CCN(C(=O)OCc3ccccc3)C2)C1=O +C=CCNC(=O)CCNC(=O)c1ccc(C(C)(C)C)cc1 +CCOC(=O)c1c(C)[nH]c(-c2ccc3c(c2)OCO3)c1N +COc1ccc(CN(C)C(=O)CCC(C)(C)C)cc1 +Cc1cc(C)n(-c2ccc(NC(=O)CSc3nncs3)cn2)n1 +NC(=O)NCc1ccc(NC(=O)c2cc[nH]n2)cc1 +CCOc1ccc(C2=CCN(C(=O)C3CC4CCC3O4)CC2)cc1 +CC1CN(C(=O)Nc2ccc(F)c(C#N)c2)CC(c2ccccc2)O1 +CC(NC(=O)N1CCC(C(N)=O)CC1)c1cccc(N2CCCC2)c1 +Cc1csc(S(=O)(=O)Cc2cccc(C(=O)N(C)C)c2)n1 +OCCN1CCN(c2ncc(-c3cc4ccccc4s3)cn2)CC1 +N#Cc1ccc(S(=O)(=O)NCCCc2ccccc2)cc1 +CCOc1ccccc1C(=O)Nc1cccnc1-n1cccn1 +CC(=O)c1cccc(OCC(=O)NCc2ccccc2-n2ccnc2)c1 +O=C(NCc1cccc(-n2cccn2)c1)C1CCC(=O)N(C2CC2)C1 +CC(C)c1ccc(CN2CCN(C(=O)C3(O)CCOCC3)CC2)cc1 +O=C(Cn1nc2ccccn2c1=O)Nc1cnccn1 +O=C(NCc1ccon1)c1cc(CN2CCc3ccccc3C2)on1 +COc1ccc(-c2cc(COC(=O)c3ccco3)no2)cc1OC +O=C1CCCCCC1Sc1nncn1-c1ccccc1 +O=C(CN1CCOc2ccc(F)cc21)N1CCN(C(=O)C2CC2)CC1 +O=C(NC1CCCC1)c1cc(NC(=O)C2CC2)n(-c2ccccc2)n1 +O=C(C1CC1)N1CCC(n2nnc3ccccc3c2=O)CC1 +O=c1[nH]c(CNc2nccc(CCC(F)(F)F)n2)nc2ccccc12 +CCCN(CC(=O)Nc1ccccc1C)C(=O)c1ccc(F)nc1 +CCC(C)N(C)C(=O)Nc1ccc(F)c(NC(C)=O)c1 +c1csc(CN2CCC3OC(COCC4CC4)CCC32)n1 +Cc1cc(C2CCCN(Cc3ccccc3C#N)C2)n[nH]1 +c1cncc(-c2ccnc(NCCCn3nnc4ccccc43)n2)c1 +CCC(O)CN1CCN(c2ccccc2F)CC1 +CC(C)c1cccc(OCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1 +Cc1c[nH]c(=NC(=O)c2ccc(Br)c(O)c2)[nH]1 +O=C(Nc1nccs1)c1ccc(C#CCO)cc1F +Cc1cc(C(=O)Nc2ccc(C)c(F)c2)ccc1N +CCOc1ccc(-c2cc(C(F)(F)F)nc(N)n2)cc1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)NCCS3)nc1 +CC(=O)N1CCCC1C(=O)Nc1ccc(C)cc1C +COc1ccc2oc(C(=O)NCCCO)c(C)c2c1 +O=S1(=O)N=C(Cl)Nc2c(Cl)cccc21 +O=S1(=O)CCCN1Cc1noc(-c2ccoc2)n1 +Cc1cccc(NC(=O)NCC(=O)N2CCc3cc(F)ccc3C2)c1 +COC(=O)c1ccc(C(=O)Nc2nnc(-c3cccc(F)c3)o2)cc1 +CC(=O)N1CCCc2cc(NC(=O)CCOC(C)CC(C)C)ccc21 +O=C(C(Cc1c[nH]cn1)n1cccc1)N1CC2CC3CC(C2)CC1C3 +CC(O)(CC(=O)Nc1cccc2cn[nH]c12)c1ccccc1 +CN(C(=O)CC(C#N)c1ccc(Cl)cc1)c1ccccc1 +CC(=O)Oc1ccc(C(=O)Nc2cccc(F)c2)cc1 +CCS(=O)(=O)c1ccc(NCC(=O)Nc2cc(C)on2)cc1 +CC(C)C(=O)N1CCC(C(=O)N(C)c2cccc3ncccc23)CC1 +CC1CCN(S(=O)(=O)c2ccccc2F)C(C)C1 +Cc1ccccc1N1CC(C(=O)N2CCC(C(N)=O)CC2)CC1=O +CCOc1ccc(C(=O)NCCCO)cc1NC(C)=O +Cc1ccc2c(CC(=O)N3CCOCC3)cc(=O)oc2c1 +CC(C)(CNC(=O)c1cnc(C2CCCO2)s1)c1ccc(F)cc1 +COc1cccc(NC(=O)C(O)c2ccccc2)c1 +CCN(CCC#N)S(=O)(=O)c1cnc2c(Cl)c(C)nn2c1 +Cc1c(C)c(C)c(S(=O)(=O)NCCC(=O)NC(C)C)c(C)c1C +Cc1c(Cl)cc(C(=O)NCCN(C)S(C)(=O)=O)cc1Cl +CNC(=O)C1CCC(NC(=O)CCC(=O)OC)CC1 +CC(C)(C)OC(=O)N1CCC(CS(=O)(=O)c2nccs2)C1 +CCOC(=O)CC(F)(F)C1CCN(C(=O)OC(C)(C)C)CC1 +CCNC(=O)c1ccc(CNC(=O)c2cc(C)oc2C)cc1 +N#Cc1ccc(N2CCN(C(=O)CNC(N)=O)CC2=O)cc1 +Cc1cc(C)c(NC(=O)COc2ncnc3ccccc23)c(C)c1 +COc1ccccc1OC(C)C(=O)N(C)c1ccccc1 +Cc1cc(C(=O)Nc2c(F)cc(F)cc2Br)c(C)o1 +CCc1nc(-c2ccc(F)c(Br)c2)c(N)n1N +c1ccc(CCCNc2ccccc2N2CCOCC2)nc1 +CC(=O)N1CCN(C(=O)c2cc(Br)cs2)CC1 +CCOc1ccc(-c2cc(=O)n(CC(=O)N3CCCC3)cn2)cc1 +Cc1noc(C)c1CC(=O)N1CCCC1c1ccc(F)cc1 +CC(=O)Nc1ccc(OC(=O)Nc2ccc(C)c(Cl)c2)cc1 +CC(OC(=O)c1ccn[nH]1)c1ccc(F)cc1F +CCn1c(=O)c2ccccc2n2c(CN3CCOC(C)(C)C3)nnc12 +COc1ccc(C)cc1-c1[nH]c(=O)c(C#N)cc1C +Cc1nn(C)c2ncc(NC(=O)CCCC(=O)N(C)C)cc12 +Cc1ccc(NC(=O)NCCc2nc3ccccc3[nH]2)cc1 +CCn1nc(C(C)C)cc1C(=O)C(C#N)c1ccccn1 +Cc1nnc(NC(=O)CCc2cnn(-c3ccccc3)c2)s1 +COc1ccc(CCCC(=O)N2c3ccnn3C(C)CC2C)cc1 +CC(C)C(NS(C)(=O)=O)c1ccc(Cl)cc1 +O=C(CCc1nc[nH]n1)N1CCc2cc(F)ccc2C1 +CCc1ccc(C(=O)Nc2cccn(Cc3ccccc3)c2=O)o1 +Cc1ccc(C)c(OC(C)C(=O)N2CCN(CCC#N)CC2)c1 +CC(=O)c1sc(C(N)c2ccc(O)cc2)nc1C +CN(Cc1nc2ccc(F)cc2[nH]1)C(=O)c1ccc(-c2cc[nH]n2)cc1 +Cn1cc(C(=O)N2CCC(c3ccc4ccccc4c3)C(O)C2)cn1 +CCn1cnnc1-c1ccccc1NC(=O)Nc1cnn(C)c1 +O=C(CC(F)(F)F)Nc1ccc(CN2CCOC2=O)cc1 +COc1cc(CN2C(=O)CCC2CO)cc(OC)c1OC +CC1CCC(N(C)C(=O)Cn2c(=O)oc3ccccc32)CC1 +CC(=O)c1ccc(N2CCN(c3cc(C)nc4cc(C)nn34)CC2)cc1 +COc1ccc(CNC(=O)C(C)Oc2ccccc2)cc1 +O=C(Nc1ccc(OC(F)F)c(F)c1)C1CCOC1 +Cn1ccc(CNC(=O)NCC2(c3ccc4c(c3)OCO4)CC2)c1 +O=C(c1ccc2c(c1)nc1n2CCCCC1)N1CCOCC1 +CNC(=O)CN(C)C(=O)C(C)Cc1cccc(F)c1 +COCCn1c(=NC(=O)c2ccno2)sc2cc(F)cc(F)c21 +COc1ccc(F)c(NC(=O)c2c[nH]nc2-c2ccc(F)cc2)c1 +COc1ccc(-n2nnnc2SCC(O)c2ccccc2F)cc1 +CCc1cc2c(N3CCOCC3)nc(-c3cccnc3)nc2s1 +CCN1CC(C(=O)NCCc2cccc(Cl)c2)CC1=O +COC(=O)c1cccc(NC(=O)Cn2ncc3c(=O)[nH]cnc32)c1 +COc1ccc(F)cc1C1CCC(OC)c2nc(N)nn21 +CC(C)Oc1ccc(NC(=O)NCCO)c(F)c1 +Cc1ccc2cc(C(=O)Nc3cccnc3-n3ccnc3C)[nH]c2c1 +O=C(Cc1csc(-n2cccc2)n1)Nc1ccc2c(c1)OCCO2 +COc1cccc(C2CCN2C(=O)c2ccc3oc(C)cc3c2)c1 +COc1ccc(Cl)cc1NC(=O)c1ccc(C(N)=O)cc1 +CCC(C)NC(=O)c1cnc2c(c1)c(=O)n(C)c(=O)n2C +CCOc1ccc(NC(=O)c2cnc3ccc(C)cn23)cc1 +NC(=O)CCCC(=O)N1CCOC(c2ccc(Cl)c(Cl)c2)C1 +CC(C)(C)c1ccc(S(=O)(=O)NCCC(N)=O)cc1 +O=C1Cc2cc(NC(=O)c3ccc(F)cc3F)ccc2N1 +CC(=O)c1ccc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)cc1 +CC(=O)N1CCN(Cc2ccccn2)CC2(CC(=O)N(C)C2)C1 +O=C(Nc1ccc(F)cn1)C1(c2ccc(F)cc2)CC1 +CC1(C(=O)N2CCOC(C(N)=O)C2)CCCc2ccccc21 +CCn1c(SC(Cc2ccccc2)C(=O)NC)nc2cnccc21 +CCOC(=O)c1cnc(Nc2nc(C)c3cc(C)ccc3n2)nc1C +O=C(CCn1nc2ccccn2c1=O)OCC1CCCCO1 +COc1ccc(C(C)NC(=O)c2ccc3c(c2)OCO3)cc1OC +O=C(CN1CCN(c2ncccn2)CC1)N1CCC2(CCCO2)CC1 +O=S1(=O)N=C(NCCOc2ccccc2F)c2ccccc21 +CN(Cc1cccc(C#N)c1)C(=O)CCC(=O)c1ccc(F)cc1F +NC(=O)C(Sc1nccn1-c1cccc(Cl)c1)c1ccccc1 +COC(=O)CNC(=O)C1CC(=O)N(c2ccccc2OC)C1 +CCCSc1nc2n(n1)C(c1ccncc1)C(C(N)=O)=C(C)N2 +O=C(c1ccc2c(c1)OCO2)N1CCCSc2ccccc21 +CCCN1C(=O)CCc2cc(NC(=O)c3ccc(C#N)cc3)ccc21 +CNC(=O)c1cn(C)nc1CC1CCN(C(=O)C(C)(C)C)CC1 +O=C(Nc1ccc(-n2cc(Cl)cn2)cc1)C1CCCO1 +CC(=O)NCc1ccc(C(=O)NC(C)C2CCCCC2)s1 +COc1ccccc1-c1noc(CSc2ncnc3nc[nH]c23)n1 +Fc1ccccc1C1CC(c2ccccc2)=Nc2ncnn21 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)NC(C#N)C(C)(C)C)ccc21 +Cc1cc(=O)c(C(=O)N(C)c2ccccc2)nn1-c1ccccc1 +Fc1cccc(C=Cc2nn3c(-c4cccnc4)nnc3s2)c1 +COc1cc(C)sc1C(=O)NCCc1nc(N)no1 +Nc1cccc(-n2c(CO)nc3cc4c(cc32)OCCO4)c1 +COc1ccc(C(NC(=O)CN2CCCCCC2=O)C(C)C)cc1 +CCNc1cccc(C(=O)N(CC(C)C)C(C)C)n1 +CCCCNC(=O)C1CCC(C)N(C(=O)C2CC(=O)N(C)C2)C1 +CC1(C)C(=O)OCCN1S(=O)(=O)c1ccc(Br)cc1 +CC(OCC1CCCO1)c1nc(CC(=O)NC2CCCC2)no1 +CCOc1ccc(OC(=O)CSc2ccncc2)cc1 +N#Cc1cccnc1NCCNC(=O)N1CCn2c1nc1ccccc12 +CC(C)CN(C)C(=O)c1csc(-c2cnn(C)c2)n1 +NC(=O)c1cc(N2CCOC(c3ccsc3)C2)nc2ccccc12 +CCC(C)C(N)C(=O)OCc1ccc(Cl)cc1 +CCOC(=O)N1CCN(c2ccc(C#N)cc2F)CC1 +CCCC(C)(C)NC(=O)Nc1ccc(C(=O)N(C)C)c(C)c1 +O=C(NCCNC(=O)c1ccco1)c1cnn(-c2ccc(F)cc2)n1 +CC(Sc1n[nH]c(=O)n1C1CC1)C(=O)N1CCCC1 +CCCCc1nc(CN2CCN(C(=O)OC(C)(C)C)CC2)no1 +COc1c(O)c(C)c2c(c1OC)OC(C)(C)CC2 +CCCc1nc2cc3c(cc2n1CCO)OCCO3 +Cc1occc1-c1nc(CC(=O)Nc2ccccc2Cl)no1 +COc1ccccc1-c1nnc(-c2cc(OC)c(OC)c(OC)c2)o1 +COc1ccc(-c2n[nH]c3c2C(CC#N)CCC3)cc1 +Cc1ccc(CN2C(=O)CCC2C(=O)NCc2ccccn2)o1 +O=C(CCNC(=O)c1ccc(Br)cc1)Nc1ccccn1 +CC(C#N)(NC(=O)COc1ccccc1Br)C1CC1 +O=C(Nc1nnc(C2CCCCC2)s1)C1CCCC1 +O=C(c1cc(F)cc(F)c1)N1CCC(c2n[nH]c3ncccc23)CC1 +Cc1noc(CCCC(=O)Nc2cc(C)on2)n1 +COc1cccc2cc(C(C)NC(=O)c3ccoc3)oc12 +COCC(=O)N1CC(C(=O)N2CCOCC2)CCC1c1ccccc1 +Cc1ccc(C2CC2C(=O)N2CCCC(n3cccn3)C2)s1 +Cc1cccc(NC(=O)C(C)NS(=O)(=O)c2cccs2)n1 +CC(=O)NCc1nc2ccccc2n1CCOc1cc(C)cc(C)c1 +CC(CO)C(C)NC(=O)NCCCC(=O)N1CCc2ccccc21 +Nc1nccnc1C(=O)NCCCNC(=O)c1ccccc1F +CCOC(=O)CN(CC)C(=O)c1cc(Cl)ccc1OC +CCCN(CC(=O)NC)C(=O)Cc1cccc(O)c1 +CCOC(=O)CC1NCCc2c(OC)ccc(Cl)c21 +CC1CCCCC1NC(=O)COC(=O)C1COc2ccccc2O1 +CCCC1CCC(n2c(N)cc(=O)[nH]c2=O)CC1 +COc1ccc(NC(=O)c2ccccc2F)cc1NC(C)=O +CCc1nc(C(C)NC(=O)CCc2cc(Cl)cs2)cs1 +Cc1ccc(C(C)NC(=O)Nc2cnn(CC3CCCO3)c2)o1 +Cc1ccccc1OC1CCN(C(=O)Cc2cccnc2)CC1 +Cc1cc(NC(=O)Cc2noc3ccccc23)c2ncccc2c1 +CSc1cccc(NC(=O)NCc2cc(Cl)ccn2)c1 +O=C(c1ccc(C(F)(F)F)cc1)N(Cc1ccsc1)C1CC1 +CC(C)CNC(=O)c1nccn1-c1cccc(C#N)c1 +COCCCn1ccc(NC(=O)N(C)C(C)CC#N)n1 +Cc1cc(C)n(CC(C)CNC(=O)N2CCOC(C)(C)C2)n1 +CC(C)c1nnc(C2CCN(C(=O)c3cccs3)CC2)o1 +Cc1ccc(CC(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)cn1 +O=C(CNc1ccccc1C(=O)N1CCOCC1)Nc1ccccc1 +Cc1nc(CNC(=O)NCc2ccn(-c3ccccc3)n2)c(C)s1 +CC(C)Cc1cc(C(=O)Nc2nc(CN3CCOCC3)cs2)[nH]n1 +CC(NC(=O)CCn1cnc2sccc2c1=O)c1ccccn1 +COc1ccc(Cl)cc1-n1ccnc1SCC(N)=O +N#Cc1ccc(N2CCCC(NC(=O)c3n[nH]c(=O)[nH]3)C2)c(F)c1 +CN1CC2(CCN(C(=O)c3cc(-c4ccccc4)on3)CC2)OC1=O +CC(=O)c1cccc(NC(=O)Nc2cn(C)c3ccccc23)c1 +CC1CCC(N(C)C(=O)CN2CCN(CC(F)F)CC2)CC1 +O=C(CN1C(=O)COc2ccccc21)Nc1ccc(-n2cccn2)cc1 +CCC(C)c1noc(C2CCN(C(=O)C3CCCO3)CC2)n1 +Fc1ccc2nc(COC3CN(Cc4ccccn4)CC3F)[nH]c2c1 +CNC(=O)Cc1nc2scc(-c3ccc(Cl)cc3)c2c(=O)[nH]1 +CC1CCN(C(=O)c2ccc(Br)cc2F)CC1 +CC(C)N(C)S(=O)(=O)NC1C2CC3CC(C2)CC1C3 +CCS(=O)(=O)c1ccc(O)c(-n2cnnc2)c1 +CC(NC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1)c1ccccc1 +O=C(Cc1ccccc1)NCC(=O)N1CCCC(C(F)(F)F)C1 +CCCCn1c(N)c(Br)c(=O)[nH]c1=O +Cc1ccc2[nH]nc(C(=O)NCc3ccnc(OC4CCC4)c3)c2c1 +Cc1c(C(=O)NCC(C)c2cccs2)cnn1-c1ccncc1 +CCC(CC)C(=O)NCC#Cc1ccccc1C(=O)NC +OC(C1=CCC(Cl)(Cl)C=C1)c1ccccc1 +O=C(NCCCN1CCOCC1)C1(c2cccc(Cl)c2)CC1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ncco1 +COc1cc(C)c(C(O)C(=O)N(C)C)cc1C(C)C +Cn1nc2n(c1=O)CCN(C(=O)Nc1ccc(C(F)(F)F)cc1)C2 +Cn1nc(-c2ccc(Cl)cc2)cc1C(=O)NC1CC1 +Cc1ccccc1NC=Cc1nnnn1-c1ccccc1 +O=C(NCc1nc2ccccc2[nH]1)c1ccc(O)c(Cl)c1 +C#Cc1cccc(NC(=O)c2c(O)cc(F)cc2F)c1 +CCc1nc(CC(=O)Nc2ccc(C(=O)NCC(C)C)cc2)cs1 +Cc1cc(Cl)ccc1Oc1ccc(S(N)(=O)=O)cc1 +CCN(CC)S(=O)(=O)N1CCN(c2cnccn2)CC1 +CCS(=O)(=O)c1ccc(NC(=O)c2cccc(C)c2)cc1 +COc1cccc(C(C)=c2sc3n(c2=O)CCN=3)c1 +CC(C)(C)n1cc(NC(=O)c2cnn(-c3ccc(Cl)cc3)c2)cn1 +Cc1cc(C(=O)N2CCCc3ncccc32)sc1C +CCOC(=O)CC(C)CNC(=O)c1ccn2ccnc2c1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)CCCn1cncn1 +COc1ccc(C2NC(=O)NC(C)=C2C(=O)OC(C)(C)C)cc1OC +O=C(Nc1n[nH]c(C2CCC2)n1)C1CCC(F)(F)CC1 +Cc1nc(CN2CCOC3C(OCc4ccccn4)CCC32)cs1 +CN(C(=O)c1cn(C)nc1-c1cccs1)c1ccc(F)cc1 +CCOCc1cccc(S(=O)(=O)NCC2CCCC2)c1 +CCNS(=O)(=O)c1ccc(NC(=O)N(CC)CC)cc1 +COC(=O)c1ccc(-c2nnn(Cc3n[nH]c(=O)[nH]3)n2)cc1 +CN(CC(=O)Nc1ccc(Nc2ccccc2)nc1)S(C)(=O)=O +CCC(NS(=O)(=O)N(C)C)c1cccc(Cl)c1 +CC(C)(C)OC(=O)N1CCC(C(=O)C(C#N)c2ccccn2)C1 +Cc1cc(CNC(=O)c2cn(-c3ccccc3)nn2)c(C)o1 +CCOc1ccc(C(O)CNc2c(C)cc(C)cc2C)cc1 +Cc1cccc(NC(=O)c2nn(-c3ccccc3)ccc2=O)c1 +Cc1cc(-c2nn3c(COc4ccc(Cl)cc4)nnc3s2)[nH]n1 +O=C(Nc1ccncc1)C1CCN(C(=O)c2cccc(Cl)c2)CC1 +Cc1cc(OS(=O)(=O)c2ccc3c(c2)OCCO3)ccc1Cl +Cn1nc(CC(=O)N(CC2CCOC2)C2CC2)c2ccccc2c1=O +CCNc1ncc(C(=O)N2CCC(C#N)(c3ccccc3)CC2)cn1 +CCc1nnsc1C(=O)NC(C)CCc1ccccc1 +Cc1cc(NC(=O)CN2CCN(Cc3cccs3)CC2)on1 +CCCNC(=O)CNS(=O)(=O)c1ccc(C)cc1C +CCCc1nnc(N2CCC3(CCCN(C4CCCC4)C3=O)C2)s1 +CC(Oc1ccccc1F)C(=O)Nc1ccnn1Cc1ccccc1 +C#Cc1cccc(N(CC(N)=O)Cc2cccs2)c1 +CC1CCC(NC(=O)N(C)C(C)c2cccnc2)CC1 +Cc1ccccc1CC(=O)Nc1cccn(C)c1=O +COCC(NC(=O)c1ccc(OC(C)(C)C)cc1)C(N)=O +COCCOc1cc(C)nc2cc(C3CCOCC3)nn12 +CCC(C)C(C(=O)Nc1nnc(C)s1)c1ccccc1 +COC(=O)C(O)(CC(=O)Nc1ccc(C)c(C)c1)C(F)(F)F +CC(=O)Nc1ccc(C23COCC(=O)N2CCCN3)cc1 +COc1ncccc1C(=O)N(CCO)C1CCCC1 +NC(=O)c1cccc(CNCCc2nc(-c3ccccn3)cs2)c1 +Cn1c(C(=O)NC(CO)CO)c(Cl)c2ccccc21 +c1ccc(-c2ccc(NCCn3ccnc3)nn2)cc1 +Cc1noc(COC(=O)c2sc3ccccc3c2C)n1 +Nc1nc(-c2ccccn2)cc2c(Cl)cccc12 +Cc1csc(N(C)C(=O)c2cnn(C)c2-n2cccc2)n1 +CC(=O)Nc1ccc(NCc2c(F)cccc2Cl)cc1 +Cc1cn2c(CN(C)C(=O)CCOC(C)C)c(C)nc2s1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)c1cc(F)ccc1F +CN(Cc1cccc(OC(F)(F)F)c1)C(=O)C1CCCOC1 +CCn1nccc1CN(C)C(=O)Cc1nonc1N +Cc1cc(C)n2c(CN3CC(C)OCC3(C)C)cnc2n1 +C=CCNS(=O)(=O)c1sccc1Br +NC(=O)CSc1ncc(-c2ccc(Cl)cc2)o1 +COc1cccc2c(C)c(C(=O)NC(C)C(=O)N3CCOCC3)oc12 +CCCOC(=O)C1CC(=O)N(Cc2ccccn2)C1 +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)N(C)Cc1cccs1 +CCC1CN(C(=O)C(C)Cc2cccs2)CC1N1CCOCC1 +Nc1nc2c(c(=O)[nH]1)CCN(C(=O)c1cc(C3CC3)n[nH]1)C2 +CC(=O)Oc1ccc(CCNCc2ccccc2)cc1 +NC(=O)c1cccc(CNC(=O)C2CC2c2ccc(F)cc2)c1 +CCOc1cccc2cc(-c3ccccn3)c(=O)oc12 +CCC(NC(=O)CNc1ccc(F)cc1)c1ccccc1 +Clc1cc(CNCc2nnc3n2CCC3)cc2c1OCCCO2 +CCOc1ccc(NC(=O)N(C)CCc2noc(C)n2)c(F)c1 +CC(C)c1noc(C(C)Nc2cccc(N3CCOC3=O)c2)n1 +Cc1cc2cc(NC(=O)c3cc(=O)c4ccccc4o3)ccc2[nH]1 +O=C(NCCCn1cccc1)C1(c2ccccc2)CCOCC1 +CCCNC(=O)Cn1c2ccccc2c2nc3n(c(=O)c21)CCS3 +COCC(=O)N1CCN(C(=O)NCc2ccccc2C)CC1 +CCCn1nnnc1NCc1cccc(OC)c1OC +CCN(C(=O)c1cnc2snnc2c1)c1ccccc1 +Nc1ccc(Br)c2[nH]c(-c3cc[nH]c3)cc12 +Cc1csc(C(C)CNC(=O)Nc2ccccc2N(C)C)n1 +N#Cc1ccc(NC(=O)N(Cc2ccccc2)CC(F)F)cc1 +O=C(NCCC(=O)N1CCCCC1)c1n[nH]c(=O)c2ccccc12 +COCCC(=O)N1CCC(c2ccc(Nc3ncccn3)cn2)CC1 +COc1ncccc1CNC(=O)c1cc(Cl)ccn1 +COC(=O)C1=C(C)NC(=O)CC1c1ccccc1F +C=CCNC(=O)CN1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +Cc1ccc(C(C)NC(=O)Nc2cc(Cl)ccc2C(=O)N(C)C)o1 +COCc1nnc(NC(=O)CCc2nc3ccccc3[nH]c2=O)s1 +CN(C(=O)c1cccs1)C1CCOC(C)(C)C1 +Cc1ccc(C=Cc2c(CO)nnn2-c2nc(C)cs2)cc1 +COc1cccc(NC(=O)c2cc3c([nH]c2=O)CC(C)(C)CC3=O)c1 +COCCNS(=O)(=O)c1cc(C)c2c(c1)C(C)(C)C(=O)N2C +COCc1n[nH]c(-c2cccc(NC(=O)c3c(C)noc3C)c2)n1 +Cc1nn(-c2nc3ccccc3s2)c2c1C(=O)CCC2 +CC(C)N(C)S(=O)(=O)NC(CO)Cc1c[nH]c2ccccc12 +CC(=O)c1ccc(C(=O)Nc2ccc(Oc3ccncc3)cc2)cc1 +CC(C)(C)CCNC(=O)C1CCCCN1S(C)(=O)=O +O=c1c2ccsc2ncn1Cc1ccccc1F +Cc1cccc2c(CC(=O)Nc3nc(C4CC4)cs3)c[nH]c12 +CC(=O)Oc1cc2ccccc2cc1C(=O)Nn1cnnc1 +Cc1cc(C(=O)NC2c3ccccc3CC2O)no1 +COc1ccc(F)c(NC(=O)COc2cccc(C(N)=O)c2)c1 +NC(=O)c1cc(N)cnc1OCC1CCOCC1 +COCC(=O)NC(C(=O)Nc1ccnc2ccnn12)C(C)C +Cc1cc(C)c(C(=O)NCCc2cc3ccccc3[nH]2)c(=O)[nH]1 +CC(=O)NC1CCCN(Cc2nc3sc(C)c(C)c3c(=O)[nH]2)C1 +O=C(NCCCS(=O)(=O)c1ccccc1)c1csnn1 +CNC(=O)CSc1nnc(-c2ccc(C(C)(C)C)cc2)o1 +Nc1nonc1-c1nc(-c2cccc(O)c2)cs1 +OCCCc1cnc2c(c1)c(-c1cccs1)nn2CCO +CCc1nc(CNc2cccc(-n3nnnc3C)c2)no1 +CCc1nc2n(n1)CC(Nc1ncnc3ccsc13)CC2 +O=C(NCCOc1ccc(Cl)cc1)c1cc2cccnn2c1 +COc1ccccc1-c1nn2c(C(F)(F)F)nnc2s1 +CC(C)OCc1ccccc1Cn1c(=O)[nH]c2ccccc2c1=O +O=C(CCc1ccncc1)Nc1cccc(C(=O)C2CC2)c1 +CC1CC1c1ccc(CN(C2CC2)S(=O)(=O)N2CCCCC2)o1 +Cc1ccc(C(=O)N2CCOC3CCC2C3OCc2ccncc2)o1 +Cc1cc(C)c(NC(=O)c2ccc(C)c(N)c2)c(C)c1 +CCCCc1ccc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)cc1 +Cn1cnn(CC(=O)OCC2CCN(CC(F)(F)F)CC2)c1=O +CN(CCCN1CCOCC1)Cc1nc(-c2ccccc2)no1 +Cc1ccc(CC(=O)Nc2cccc(OCC(=O)N(C)C)c2)cc1 +Cc1ccc(NCc2cccc(C(N)=O)c2)c(Cl)c1 +O=C(NCc1ccc(OC(F)F)cc1)NCc1ccco1 +Cc1cc(NC(=O)NC2(c3ccc(F)cc3)CCC2)n(C)n1 +O=C1CN(C(=O)NCc2ccc3c(c2)OCO3)C2CCCCC2N1 +Cc1nc(CNC(=O)C2(C)Sc3ccccc3NC2=O)cs1 +Cc1ccc(F)cc1NC(=O)CSc1nnc(-c2ccncc2)o1 +C=CCNC(=O)c1nc(CC(=O)Nc2cc(C)on2)no1 +CCOc1ccc(OCC(=O)N2CCC3(CC2)OCCCO3)cc1 +NC(=O)c1ccc(CNc2ncnc3ccc(F)cc23)cc1 +Cc1cc(CNC(=O)c2cc(C3CC3)on2)ccc1F +CCCC(NC(=O)c1n[nH]c(N)n1)c1cccs1 +COC(=O)Nc1ccc(CNC(=O)c2cn3ccc(C)cc3n2)cc1 +COc1c(F)ccc2c1C(c1ccc(C#N)cc1)NCC2 +COc1cc(C)ccc1OCCn1cnc2ccccc21 +COCC(O)CN(C)S(=O)(=O)c1cc(N)cs1 +CCOC(=O)c1ccc(Nc2nc(C)ccc2N)cc1 +Nc1nc(N2CCN(c3ccc(Cl)cc3)CC2)c2nc[nH]c2n1 +CCCc1cc(N2CCN(c3cccc(O)c3)CC2)n2nccc2n1 +Cc1cc(C(=O)Nc2cc(C)nn2CCC#N)c2c(C)nn(C)c2n1 +CC#CC1NCCc2ccc(OC(C)C)c(OC)c21 +O=C(C1CC1)N1CCNC(c2nc3ccccc3[nH]2)C1 +CCOC(=O)c1cc(NS(=O)(=O)c2ccc(C)cc2C)c[nH]1 +COc1cccc2c(=O)c(C(=O)Nc3nncs3)c[nH]c12 +CCn1cc(C(=O)Nc2cnc3cc(OC)ccc3c2)c(C)n1 +CC(CNc1ccc2nnnn2n1)CN1CCCC1=O +Cc1ccccc1C(NC(=O)NCC(=O)NC1CC1)C(C)C +COC(=O)CNC(=O)C(C)(C)Oc1ccc(Cl)cc1 +Cc1cc(Cl)ccc1-c1ccc(C(=O)NC(C)CO)o1 +O=C(Nc1cc(-c2ccncc2)no1)C1CCCCC1 +Cc1nc(C(C)C)sc1C(=O)N1CCCC1c1cccnc1 +CC(C)(C)OC(=O)N1CCC(N(CCC#N)Cc2cccnc2)CC1 +CC1CCN(C(=O)c2nn(C)c3c2COc2ccccc2-3)CC1 +COC(=O)C(CO)NS(=O)(=O)c1ccc(Br)cc1 +COC(=O)c1ccc(CN2CC(C)OC(C)C2)cc1 +COC(=O)c1cc(NC(=O)CSc2ncn[nH]2)ccc1Cl +Cc1ccc(C2NCCc3ccc4c(c32)OCCO4)cc1F +O=C(c1cccs1)N(Cc1ccccn1)c1ccccc1 +CC1N(C)C(=O)COC12CCN(C(=O)CCc1ccccc1)CC2 +CCC(Sc1cc(C)ncn1)C(=O)Nc1ccc(F)cc1 +O=C(Nc1nc(C2=NC=CC2)cs1)c1cccc(Br)c1 +Cc1ccc(CC(=O)Nc2nnc(-c3ccn(C)n3)o2)c(C)c1 +COc1ccc(C2CCCCCN2C(=O)Cn2cnc(C#N)n2)cc1 +Cc1ccccc1CNC(=O)c1ccc2ncsc2c1 +Cc1cc(=O)c2cc(C(=O)Nc3cccc(Cl)c3)ccc2[nH]1 +Cc1cc(C(=O)OCC2CCC(=O)N2)c(C)n1Cc1ccccc1 +Cc1cc(C)cc(C(=O)Nc2cc3c4c(c2)CCC(=O)N4CCC3)c1 +COc1ccc(C(=O)NCc2cn(C)nc2C)c(OC)c1 +COc1cccc2c1OCC(Cc1ccc(C)nc1C)C2 +Cc1ccc(CNC(=O)Nc2ccnc(C(=O)N(C)C)c2)cc1F +CC(=O)Nc1cccc(NC(=O)CNC(=O)NCc2ccco2)c1 +Cc1cccc(NCC(=O)NC(C)(C#N)C2CC2)c1C +Cc1ccc(CCC(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)cc1 +COc1cc(C)c(C(=O)Nc2ccccc2-c2ncc[nH]2)cc1OC +CCOC(=O)NC1CCCN(C(=O)C(C)c2c(C)nn(C)c2C)C1 +CCOC(=O)c1cnn2ccn(Cc3ccccc3Cl)c12 +Cc1c(CCNC(=O)Cc2cccc(OCC#N)c2)cnn1C +CC(=O)Nc1ccc2oc(-c3ccc(O)c(Br)c3)nc2c1 +CCCS(=O)(=O)N1CC2CCC1CN(c1ncccn1)C2 +c1ccc(N2CCOCC3(CCCN(c4ccncn4)C3)C2)cc1 +FC(F)(F)c1cccc(CNCc2ncc(-c3ccco3)s2)c1 +O=C1CCCN1c1ccccc1NCc1ccc(Br)cc1 +CN1CCN(C(=O)C2(c3ccccc3)CCCC2)CC1 +Cn1c(CCNc2cc(-c3ccccc3)nc3ccnn23)n[nH]c1=O +O=C(CCn1c(=O)oc2ccccc21)OCc1ccccn1 +COC(=O)C1CCN(C(=O)CCC(C)(C)C)c2ccccc21 +Cc1cc(C)n(CC(C)CNC(=O)c2cnccn2)n1 +CC(C)(C)n1cc(C#N)cc1NC(=O)Cn1ncc2ccccc2c1=O +O=C(NC1CC1)C(c1ccccc1)N1CCCC(C2OCCO2)C1 +CC(O)CNC(=O)CCNC(=O)c1ccc(Br)cc1 +O=C1CCCCCN1Cc1cccc(F)c1C(F)(F)F +Nc1ccc(C(=O)CCC(=O)N2CCOCC2)cc1 +COCC(C)NC(=O)c1ccc2nc3c(nc2c1)C1CCC3C1 +CCCn1nnnc1COc1ccc(C(C)=O)c(F)c1 +Cc1ccc(C(=O)NCC(=O)N2CCCC(C)C2)cc1 +COc1ccc(C(=O)c2cnn(-c3ccc(Cl)cc3)c2N)cc1 +CC(Cc1ccco1)Nc1nc2ccccc2c(=O)[nH]1 +O=C(c1ccc(F)nc1)N1CCCC1c1ccc(F)cc1 +O=C(NCc1ccccc1Cl)c1cccc(-n2cnnn2)c1 +NC(=O)C1CCCN1C(=O)c1csc(-c2ccsc2)n1 +CCc1cccc(C)c1NC(=O)CSc1cccc2cccnc12 +C=CCN(CC=C)S(=O)(=O)c1c(C)noc1C +CCn1nc(C(=O)N2CCC(C(N)=O)CC2)c2ccccc2c1=O +COc1ccc(CCNC(=O)c2nonc2NC(C)=O)cc1OC +COC(=O)c1cc(N)n(-c2cc(Cl)cc(Cl)c2)n1 +Nc1ccc2c(c1)CCN2C(=O)c1cc(F)cc(F)c1 +CC(C)CNC(=O)C1(NCc2cccc(C(N)=O)c2)CCCC1 +Cc1nn(C)c2ncc(C(=O)Nc3cccc(N4CCCCC4)c3)cc12 +CN(CCC#N)C(=O)CCCNC(=O)c1ccc(Cl)cc1 +COc1ccc(C2(C(=O)N(C)Cc3cc(C)on3)CCCC2)cc1 +Cc1ccc(C)c(NC(=O)Cn2ccc3c(=O)[nH]ccc32)c1 +CCOC(CC)C(=O)Nc1cc(C(=O)N(C)C)ccc1C +CCCOc1cccc(NC(C)C(=O)Nc2c(C)nn(C)c2C)c1 +CCC(OC1CCCC1)C(=O)NC(C#N)C(C)(C)C +Cc1ccccc1-n1nnnc1SCC(=O)N1CCOCC1 +CN(CCc1ccc(F)cc1)Cc1nc(-c2ccsc2)no1 +CNC(=O)COC(=O)c1ccccc1OCc1c(C)noc1C +C#CCN1CCN(C(=O)CNc2cc(CO)ccc2Cl)CC1 +COCCNC(=O)N1CCCN(c2ncccc2C#N)CC1 +COc1ccc2c3c1OC(C)C31CC(=O)CCC1CC2 +CC(=O)c1ccc(S(=O)(=O)NCc2nc3cccnc3n2C)cc1 +NC(=O)c1ccc(C(=O)OCc2cc(Cl)cc3c2OCOC3)cc1 +O=C(Cn1ccc(=O)c2cc(Cl)ccc21)NCCc1cccs1 +CCOc1ccc(NC(=O)c2ccc(OC)nn2)cc1 +COCCNC(=O)Nc1cccc(NC(=O)c2ccoc2)c1 +CS(=O)(=O)N1CCC(C(=O)NC2CCCc3ccccc32)CC1 +CC1CCCC(OCC(=O)N2C(C)COCC2C)C1 +Cc1cccc(C(=O)Nc2ccccc2SCC(N)=O)c1C +Cc1occc1C(=O)N(C)C1CCc2ccccc21 +Cc1nn(C)c(Oc2cccc(F)c2)c1NC(=O)c1ccncc1 +CC(C)(C)NS(=O)(=O)c1ccc(C(=O)Nc2ccccc2)cc1 +O=C(CNC(=O)c1c[nH]c2cccc(F)c12)OCc1ccccc1 +COc1cc(N)cc(C(=O)N2CCCCC2C)c1OC +CCn1cc(NC(=O)NC(C)c2ccccc2Br)cn1 +CC(C)(C)c1cc(N)cc2c1OC(c1ccc(F)cc1)C(=O)N2 +CN1C(=O)C(C)(C)COc2cc(NC(=O)C3CCCC3)ccc21 +O=C(CCCc1cccs1)Nc1ccccc1-n1ccnc1 +Cc1noc(C)c1CCC(=O)Oc1cccc(Cl)c1 +FC(F)Oc1ccc(CN2CCOC3(CCOCC3)C2)cc1Cl +CC(C)C(NC(=O)NC1CC(=O)N(C2CC2)C1)c1ccccn1 +CCOc1ccccc1NC(=O)C(C#N)Cc1ccc(C)o1 +CCN(Cc1cccc(NC(=O)Nc2ccccc2Cl)c1)C(C)=O +CCC(=O)N1CCC(c2nc(C)ccc2C(=O)NC(C)CC)CC1 +COc1cccc(CCNC(=O)c2ccccn2)c1 +CCc1cc(NCCSc2ncn[nH]2)n2nc(C)c(C)c2n1 +c1coc(CN2CCc3ncnc(C4CCOC4)c3CC2)c1 +COc1ccc(C(N)=O)c(OCC(=O)C2=NC=CC2)c1 +CCNC(=O)CNC(=O)c1cn(CC(C)C)c2ccccc12 +CC(Sc1ccccn1)C(=O)Nc1ccc(C#N)c(Cl)c1 +Cc1ccc(-n2nc(C)c(C(=O)NC3CC3)n2)c(C)c1 +COC(=O)c1cc(CNC(=O)c2c(F)cccc2F)ccc1OC +Cc1cc(Br)cc(-c2cc(N)n[nH]2)c1F +Cc1ccc(-c2ncco2)cc1NC(=O)C(C)c1cccnc1 +CCNC(=O)c1ccc(CNC(=O)Nc2cnccc2C)cc1 +COC(=O)c1nn(-c2ccc(C)c(Cl)c2)nc1C +CC(C)n1ccnc(N2CCC(CO)CC2)c1=O +Cn1cc(C2CN(Cc3cccc4c3OCO4)CCO2)cn1 +O=C(Nc1c(-c2ccc(F)cc2)nc2sccn12)c1ccccn1 +COc1cccc(Cl)c1C(=O)NCC(C)(O)c1ccc(F)cc1 +CCn1ncc(-c2cc(C(F)F)nc(N3CCCC3)n2)c1C +COc1ccc(-c2n[nH]c(C3CC3)c2NC(=O)CC(C)C)cc1 +O=C(NCC1(c2ccccc2)CCC1)c1ccc2[nH]nnc2c1 +O=C1N(CC(=O)N2CCc3ccccc32)CCN1c1ccccc1 +CCOc1cc(CO)cc2c1OC(CC)C(=O)N2CCCO +CC(NC(=O)Cn1[nH]c(=O)c2ccccc2c1=O)C1CC1 +COc1ccccc1-c1noc(CN(C)C(C)c2ccccn2)n1 +CCOCCN1CCN(c2nc3ccccc3s2)CC1 +Cn1cnc(CNC(=O)NC(CC(C)(C)C)c2ccc(F)cc2)n1 +CC(C)NC(=O)C1CN(C(=O)N(C)C)CC12CCOCC2 +CC(COCC(F)(F)F)Nc1nc2c(c(=O)[nH]c(=O)n2C)n1C +C=CCc1cc(OC)ccc1OCC(=O)Nc1cc(C)on1 +CCC(COC)NC(=O)Cn1c(C2CC2)nc2ccccc21 +COC(=O)CCC1CCCCN1C(=O)CNC(N)=O +C#CCOC(=O)Cn1c2ccccc2c(=O)c2ccccc21 +O=C1c2ccccc2NC(c2c[nH]c3ccccc23)N1Cc1ccco1 +CC(=O)c1cc(-c2ccccn2)nn1Cc1ccccc1 +CCCCCNC(=O)Nc1cnn(CC(F)F)c1 +CCC(=O)N1CCC(NC(=O)NCc2ccc(C)cc2N(C)C)C1 +NS(=O)(=O)Cc1cccc(NC(=O)c2ccco2)c1 +Cc1ccc(C(=O)NCCc2c[nH]c3ccccc23)cn1 +O=C(NCc1ccc2c(c1)OCCO2)Nc1nncs1 +CCOc1ccc2c(C(=O)Nc3nccs3)cc(=O)oc2c1 +Cc1noc(C)c1CN(C)C(=O)c1nc(N2CCCC2)ncc1Cl +O=C(NCc1ccccn1)Nc1nnc(C(F)(F)F)s1 +CC(O)CNC(=O)CCCc1c[nH]c2ccccc12 +CCCCc1nc2cc(Br)cnc2n1CCC#N +COC(=O)C(C)CNC(=O)Nc1ccc(-c2nnc(C)o2)cc1 +Cc1ccc(C(N)=O)cc1S(=O)(=O)Nc1ccc(F)cc1 +CC(c1ccco1)N(C(=O)CNC(=O)Cc1ccccc1)C1CC1 +C#Cc1cccc(NC(=O)NCc2cc(Cl)ccn2)c1 +COc1ccc(OCC(=O)Nc2cc(F)c(OC)c(F)c2)cc1 +N#CCCN(Cc1cccc(-c2ccncc2)c1)CC1CC1 +Cc1cccc(OCC(O)Cn2nc(C)cc2C)c1 +Cc1cc(C)n(-c2cc(NC(=O)c3ccccc3Cl)ncn2)n1 +CNC(=O)c1cn(-c2ccc(F)cc2)nc1-c1cccc(C)c1 +O=C(c1cccc(-c2ccoc2)c1)N1CCC2(CCOC2)C1 +CCCNC(=O)c1cc(=O)c2cc(N)cc(C(C)C)c2o1 +Cc1ccc(C(=O)NCC(=O)N2CCC(CC(N)=O)CC2)cc1C +CCOC(=O)CNC(=O)Nc1ccc(Cl)cc1 +CC(C)c1cc(C(=O)N2CCCC3(CCCO3)CC2)n(C)n1 +Cc1ccnc(NC(=O)Nc2cn(C)c(=O)c3ccccc23)c1 +Cc1ccc(C(=O)Nc2ccccc2C(N)=O)cc1F +NC(=O)C1CCN(C(=O)c2cccnc2)c2ccccc21 +Nc1c(C(=O)Nc2ccccn2)cnc2c(-c3ccccc3)cnn12 +Cc1ccnn1CCc1nc(-c2ccc(F)cc2F)cs1 +O=C(c1nn2ccccc2c1Cl)N1CCOCC1 +CCc1ccc(OCC(=O)Nc2ccc(S(=O)(=O)NC)cc2)cc1 +O=C(NCC1CN2CCCCC2CO1)NC1CCC(CO)CC1 +CCC(C)NC(=O)Cn1c(=O)oc2ccc(CO)cc21 +COC(=O)c1ccsc1NC(=O)c1cccc(N(C)C)c1 +CCc1cc(C(=O)N2CCN(C(=O)C3CCCO3)CC2)[nH]n1 +CN(C)c1ccc(F)c(C(=O)Nc2ccccc2)c1 +Cc1ccc(-c2nnc(C(C)Nc3cccc4c3OCCO4)o2)cc1 +O=C(Nc1nc[nH]n1)c1ccc(Br)cc1 +COC(=O)CC(NC(=O)c1cc2ccccc2[nH]1)c1cccs1 +CNS(=O)(=O)c1cccc(CNC(=O)Nc2ccncc2)c1 +NC(=O)CCNC(=O)Nc1cccc(NC(=O)c2ccccc2)c1 +Cc1ccc(C(=O)N(C)Cc2ccc3c(c2)OCCO3)s1 +Cc1cc2c(F)ccc(C)c2nc1N1Cc2cnn(CCO)c2C1 +Nc1cccc(-c2nn3c(C4CCCO4)nnc3s2)c1 +CCc1cnc(CN(c2cccc(C(C)=O)c2)S(C)(=O)=O)o1 +CC(=O)Nc1ccc(C)c(NS(=O)(=O)c2cc(C)ccc2C)c1 +COc1ccc(NC(=O)NCCc2ccccn2)cc1OC +COC(=O)c1cc(CNC(=O)c2occc2C)ccc1OC +O=C(NCCC(=O)N1CCN(Cc2ccccc2)CC1)c1ccco1 +N#Cc1ccc(N2CCC(C(N)=O)C2)c(C(F)(F)F)c1 +CC(C)c1ccc(CNC(=O)c2cccc(N)c2)cc1 +Cc1cccc2c(C(=O)OC3COCOC3)cnnc12 +COc1cccc2cc(C(=O)N3CCC(C(N)=O)CC3)c(=O)oc12 +CCOc1ccccc1OC(=O)Cc1cccc(F)c1F +O=C(CC1CCCCC1)N1CCC(S(=O)(=O)c2ccccc2)C1 +O=C(NCC(O)C(F)(F)F)Nc1ccc(Cl)c(Cl)c1 +CN(Cc1cccs1)C(=O)c1cncc(Br)c1 +O=C(Nc1ccc(-n2cnnn2)cc1)C1CC1(Cl)Cl +OCc1ccc(CNCC2(c3ccccc3)CCOCC2)o1 +O=C(Cn1nc2ccccc2n1)N1Cc2ccccc2C(O)C1 +CCC(=O)N1CCc2c(C(=O)Nc3ccc(OC)cc3C)cccc21 +Cc1ccc(-c2cc(C(=O)Nc3nc[nH]n3)on2)cc1 +CC#CCSc1nnc(NCC(F)(F)F)s1 +N#Cc1ccc(Cn2c(=O)oc3cc(Br)ccc32)cc1 +CC1CCN(C(=O)CN2CCOc3cccc(N)c32)CC1 +Cc1ccc(C(=O)NCC2CCN(c3ncccn3)CC2)cc1 +O=C(CC1CCCCC1)NCc1cn(-c2ccccc2)nn1 +N#Cc1ccc(CNC(=O)CCOc2ccccc2F)cc1 +CCCN(CC(=O)N(C)C)S(=O)(=O)c1cn[nH]c1 +COc1ccc(OC)c(NC(=O)Cc2c(C)[nH]c(=O)[nH]c2=O)c1 +CCc1nc(NC(C)(C)CC(C)(C)C)c(N)c(OC)n1 +CCN(Cc1ccc(SC)cc1)C(=O)C1CC(=O)N(C(C)(C)C)C1 +O=C(NCCNCc1ccccc1C(F)(F)F)c1ccccc1F +Cc1nccc2[nH]c(=O)c(C(=O)NCCC(C)C)cc12 +COCC(NC(=O)Cc1cc(Cl)ccc1Br)C(N)=O +CCOC(CC)C(=O)Nc1ccc(C)c(S(=O)(=O)N(C)C)c1 +CCOc1ccc(NC(=O)N(C)CC(O)COC)cc1F +Cc1nn(C)c(C)c1NC(=O)CN1CCCCCC1=O +CCc1ccccc1N1Cc2c(N)cccc2C1=O +O=C(C1COc2ccccc2O1)N1CCCC1Cn1cccn1 +C#CCN1CCN(CC(=O)N(C2CCCC2)C2CC2)CC1 +CC1CCN(C(=O)c2csc(Nc3cccnc3)n2)CC1 +O=c1cc(CNc2ccccc2C(F)(F)F)nc2ccccn12 +Nc1cc(F)cc(Br)c1OC1CCCCNC1=O +Cc1c(Br)cccc1Cn1cncn1 +CC(=CC(=O)OCCNS(C)(=O)=O)c1ccccc1Cl +Cc1nn2cccnc2c1C(=O)N1CC(C)CN(C)c2ccccc21 +Cn1c(SCc2n[nH]c(=O)[nH]2)nnc1-c1ccccc1Cl +CC(=O)c1c(C)[nH]c(C(=O)NCC(=O)N2CCCC2)c1C +Cc1cc(C)n(C(C)C(=O)Nc2ccc(Cl)cc2Cl)n1 +Fc1cc2c(c(CSc3ncnc4sccc34)c1)OCOC2 +NC(=O)CCNC(=O)c1ccc(F)c(NC(=O)CC2C=CCC2)c1 +O=C(NCC1CC1c1ccccc1)c1ccc(OCC(F)F)nc1 +Cc1ccc(C(=O)N(C)C)cc1OCC(=O)NC1CC1 +COc1ccc(CNS(=O)(=O)c2ccc(C#N)cc2)cc1OC +Cc1cccc(Cn2nccc2NC(=O)CSc2nccn2C)c1 +CS(=O)(=O)c1ccc(NCc2ccccc2)cc1 +COC(=O)c1ccc(CNC(=O)Cn2cnc(C#N)n2)cc1 +CS(=O)(=O)N(CC(=O)NC1CC1)c1ccc(F)c(Cl)c1 +Fc1cc2c(cc1Cl)C(c1cc[nH]n1)NCC2 +C=CCOc1ccc(C(=O)NCC(C)(C)c2ccncc2)cc1 +CCC(C)N(C)C(=O)Nc1ccc(OC)c(OC(F)F)c1 +CC(C)(C)CC(=O)N1CCn2c(nnc2C(F)(F)F)C1 +COC(CNC(=O)C1CC(=O)N(C)C1)c1cccc(Cl)c1 +Cc1ccc(S(=O)(=O)NCc2ncoc2C)c(C)c1 +CC(=O)Nc1ccc(F)c(C(=O)N2CC(C)OCC2C)c1 +Cc1ccnc(SCC(C)(C#N)NC(C)C)n1 +COc1ccc2oc(C)c(C(=O)NCCCO)c2c1 +CN(Cc1ccccc1)C(=O)CN(C)c1ccccc1 +COc1cccc(OCC(=O)N2CCN(Cc3ccccc3)CC2)c1 +C=C(C)COc1cccc(C(=O)Nc2ccc(CC(=O)NC)cc2)c1 +O=C(Nc1cc(-c2ccsc2)no1)c1ccc(F)cc1 +O=C(Nc1ccc(F)cc1F)c1cccc(Oc2ncccn2)c1 +Cc1cc(C)n(-c2cccc(C(=O)Nc3ccncc3)c2)n1 +Cc1cccc(CC(C#N)C(=O)N2CCc3ccccc3C2)c1 +COc1ccccc1C(=O)NCCCn1nc(C)cc1C +COCCNC(=O)c1ccc(C#CCO)cc1F +COCCCNC(=O)c1nn(C)c(C)c1Br +CCc1ccc(C(=O)Nc2sc(C)c(C)c2C(N)=O)cc1 +CNC(=O)CN(C)S(=O)(=O)c1ccc(OC)c(OC)c1 +COCCn1cc(NS(=O)(=O)c2cccc(C#N)c2)cn1 +COc1cccc(COC(C)C(=O)Nc2cc[nH]n2)c1 +CS(=O)(=O)NCCNC(=O)NCc1ccc(F)cc1 +Cc1ccccc1SCC(=O)NC(C)c1ccncc1 +CCCn1nc(C)c(CN2CCNC(=O)C2CC)c1C +Cc1cccc(OCC(=O)Nc2ccc(S(C)(=O)=O)cc2)c1 +CC(=O)N1CCOc2ccc(S(=O)(=O)N=c3[nH]cccc3C)cc21 +CC(C)n1ccc(C(=O)OCC2CN(Cc3ccccc3)CCO2)n1 +Cn1nnnc1NCc1ccc(Cl)cc1Cl +c1cc(-c2noc(CN3CCCC(CN4CCOCC4)C3)n2)cs1 +Cc1occc1C(=O)N1CC2OCCN(C(C)C)C2C1 +Cc1ccc(-c2nnc(C(=O)NC3CC3)n2C)cc1 +C#CCn1cnc2c(cnn2-c2ccc(C)c(C)c2)c1=O +CCn1cc(C(=O)Nc2cc(C)n3nc(C(F)(F)F)nc3n2)cn1 +C=CCOC1CCN(C(=O)Cn2ccccc2=O)CC1 +Cc1nc(N(C)Cc2ccccc2)c2nnn(Cc3ccccc3)c2n1 +CCOc1ccnc(N2CCN(C(=O)Cn3nc(C)cc3C)CC2)n1 +CCCn1c(SCC(=O)c2ccccc2F)n[nH]c1=O +C#CCCCOC(=O)C(C(C)C)N1CCCC1=O +CNc1nc(-c2sc(N3CCCC3)nc2COC)cs1 +COc1ccc(F)cc1-c1ccc(C(=O)N2CCOCC2)cn1 +Cn1cc(CNC(=O)C2(c3cccc(Cl)c3)CC2)cn1 +COc1cc(C)c(Cl)cc1S(=O)(=O)N(CCO)CCO +COCc1cccc(NC(=O)CNC(=O)c2ccc(OC)cc2)c1 +Cc1nn(-c2ccc(F)cc2)c(C)c1CNCCc1ccccn1 +CCNC1=NS(=O)(=O)c2cc(OCC)ccc2N1 +CCCCNC(=O)C(N)c1ccc2c(c1)OCO2 +CCCC(=O)NCCN1CCN(S(=O)(=O)c2ccccc2)CC1 +CC(C)(CNC(=O)c1cnc(-c2ccccn2)s1)c1ccncc1 +CCC(C)Nc1ccc(S(=O)(=O)C(F)F)cc1 +CNC(=O)c1cccc(S(=O)(=O)Nc2ccccc2F)c1 +CC=CCOC(=O)C1CC(=O)N(c2ccccc2OC)C1 +O=C1CC(c2cccc(O)c2)c2cc3c(cc2N1)OCCO3 +CCC(C)NC(=O)Nc1ccccc1CN1CC(C)OC(C)C1 +Cc1ccc(NC(=O)NCC(O)c2ccsc2)cc1C +CCOc1ccc(S(=O)(=O)Cc2nc(C3CC3)no2)cc1 +Cc1cc(C)cc(C(=O)NCc2ccccc2S(=O)(=O)N(C)C)c1 +Cc1ccc(O)c(C(=O)NC(C)c2ccc(S(C)(=O)=O)cc2)c1 +CC(=O)C(C)Sc1ncnc2sc(C)c(C)c12 +NS(=O)(=O)c1ccc(-n2nnnc2-c2ccncc2)cc1 +CS(=O)(=O)NCCC(=O)NC1CCOc2ccccc21 +CN(C(=O)COC(=O)c1cc(Cl)c[nH]1)C1CCCCC1 +COC(=O)C1=C(N)Oc2cc(C)[nH]c(=O)c2C1c1cccc(OC)c1 +O=C(NCc1cc(Br)c2c(c1)OCO2)C1CC=CCC1 +CCc1nsc(N2CCCN(C(=O)CCc3cccnc3)CC2)n1 +Cc1cc(C(=O)N2CCCC2c2ccc3c(c2)OCCO3)c(C)s1 +CCOc1ccc2nc(NC(=O)C3CC4CCC3O4)sc2c1 +CN(CC1CC1)C(=O)CNC(=O)c1ccc(C#N)cc1 +O=C(NCc1ccc2c(c1)OCO2)c1ccc(N2CCOCC2)nc1 +CC1CCCCC1NC(=O)CSc1nncn1-c1ccccc1 +CC(C)(C)OC(=O)N1CC(NCc2ccccc2Br)C1 +CC(C)c1cc(OC2CC2)cc(S(N)(=O)=O)n1 +O=C(NCC(O)c1cccc(OC(F)F)c1)C1CC1 +Cc1ccc(-n2ccnc2)c(C(=O)NCc2ccccn2)c1 +COCCN1c2ccc(S(N)(=O)=O)cc2CC1C +CN(C(=O)c1cc(-c2ccco2)on1)c1nccs1 +Cc1ccc(NC(=O)CN2CCCCCC2=O)nc1 +COc1cccc(C(=O)N(C(C)C)C2CCC2)c1F +CN(Cc1ccccc1CO)C(=O)OC(C)(C)C +O=C(NCC1CCCCC1)C1CN(S(=O)(=O)C2CC2)C1 +CCN1CC(C(=O)Oc2ccc(C)cc2Br)CC1=O +CC(Nc1cccc(CO)c1)C(=O)Nc1ccccc1C#N +Cn1nnnc1-c1cccc(NC(=O)CCOc2ccccc2)c1 +Cc1cccc(-c2noc(CNC(=O)NC(C)(C)C)n2)c1 +Cn1c(SCC(=O)OC(C)(C)C)nc2ccccc2c1=O +CS(=O)(=O)N1CCCCC1C(=O)NCc1ccncc1 +COc1ccc(C2CC(C)N(C(=O)c3ccc(C)nc3)C2)cc1 +CN(Cc1cnn(C)c1)C(=O)c1cccc(C#N)c1 +Cc1csc(=O)n1CCC(=O)OC(C(N)=O)c1ccccc1 +CS(=O)(=O)N1CCCC12CCCN(C(=O)C1CC1)C2 +CNC(=O)NCC(=O)NC(c1ccccc1)c1cccc(F)c1 +CCOc1ccc(-c2c(C3CC3C)n[nH]c2N)cc1 +COc1cc(C)ccc1S(=O)(=O)N1CCC(OC)C2OCCC21 +CC(C)CCN1CC2(CCCN(c3cc(N)ncn3)C2)CCC1=O +CCOC(=O)c1c2n(c3ccc(F)c(Cl)c3c1=O)CCS2 +CCOc1ccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +CCOc1ccc(-c2nc(Cn3cnc(C#N)n3)cs2)cc1 +Cc1cccc(C)c1-n1cc2c(c(C#N)c1=O)CCCC2 +CC(C)NC(=O)C1CCC(CNC(=O)c2cc3sccn3c2)CC1 +Cc1noc(C)c1C(=O)NC1CC1c1cccc(Cl)c1Cl +Cc1nc(C2CCCN(C(=O)c3ccc(C#N)cn3)C2)sc1C +COc1ccc(Cl)cc1N1CC(C(=O)OC(C)C)CC1=O +CCN(CC(=O)N1CCOCC1)S(=O)(=O)c1ccc(Cl)cc1 +CN(C)c1cccc(C(=O)NCC2(c3ccccc3)CCOCC2)c1 +Cn1cccc(NC(=O)C2CCCCN2S(C)(=O)=O)c1=O +CC(=O)Nc1ccc(F)c(C(=O)NCC(=O)N2CCCCC2)c1 +CN(C)S(=O)(=O)NC(c1ccc2c(c1)CCC2)c1cccs1 +CCN1CCN(C(=O)C(C)n2sc3ccccc3c2=O)CC1 +O=C(NCCCNc1nc(C2CC2)ns1)C1CCC1 +Cc1oc2c3c(ccc2c(=O)c1-c1ccc2c(c1)OCCO2)OCO3 +CC(C)c1nc(CNC(=O)C2Cc3cc(F)ccc3O2)cs1 +Cc1cc(C(=O)N2CCN(c3oc(C4CC4)nc3C#N)CC2)[nH]n1 +CN(CCC(F)(F)F)C(=O)CCc1nc(C(C)(C)C)no1 +Nc1ccc2oc(=O)n(Cc3ccccc3Cl)c2c1 +CC1CCc2nc(NC(=O)Cn3ccc(=O)n(C)c3=O)sc2C1 +Cc1cccc(C(CNC(=O)N2CCCC(O)C2)N2CCOCC2)c1 +Nc1nc(N2CCCCC2)ncc1C(=O)NC1CCCCC1 +COC(=O)C(CO)NCc1cccc(C)c1Cl +COc1cccc2cc(C(=O)N(CCC#N)CCC(F)(F)F)oc12 +N#Cc1ccc(Nc2cccc(C(=O)N3CCCS3(=O)=O)c2)cc1 +C#CCOCC1CCCN(S(=O)(=O)c2ccc(Cl)cc2)C1 +Cc1ccc(CC(=O)N(C)CCc2ccc(F)cc2)cn1 +CC(C)(C)OC(=O)N1CCC(Oc2cccnc2)C1 +CC1CC1C(=O)Nc1cccc(S(=O)(=O)NCc2ccco2)c1 +Cc1cccc(C(O)CNC(C)c2ccccc2)c1 +Cn1cc(NC(=O)c2cccc(-c3ccoc3)c2)c(=O)n(C)c1=O +CC(NC(=O)Nc1ccc(F)cc1C#N)c1ccc2c(c1)OCO2 +Cc1ccc(CN(Cc2ccncc2)C(=O)c2cccn2C)s1 +CCSc1cc(C(=O)Nc2ccc(F)c(F)c2F)ccn1 +Cc1ccc(NC(=O)N(C)CC2CCCC2O)cc1S(C)(=O)=O +COc1ccccc1N1CCN(C(=O)c2cccc3c2ccn3C)CC1 +CCc1onc(C)c1NC(=O)CCOCC(C)C +CCOC12c3cc(OC)c(OC)cc3CCN1C(=O)OC2(C)C +CCCC(=O)Nc1ccc(OC(=O)c2cn(C)nc2C)c(C(C)=O)c1 +Cc1noc(NC(=O)CSc2nnc3n2CCCCC3)n1 +CCOC(C)C(=O)Nc1ccnn1Cc1ccccc1F +NC(=O)NCCC(=O)Nc1ccccc1N1CCCC1 +CCCCS(=O)(=O)N1CC(c2nc(-c3cccs3)no2)C1 +CCn1cc(C(=O)N(C)C)c(=O)c2cc(Cl)ccc21 +COC(=O)c1cc(OC)c(OC)cc1NC(=O)c1ccccn1 +CCNC(=O)CN1CCN(C(=O)c2cc(C)nc3onc(C)c23)CC1 +CS(=O)c1ccc(C(=O)Nc2cc(F)cc(F)c2)cc1 +CCOC(=O)CCNC(=O)C(N)c1ccccc1F +O=C1NCCCCC1Sc1nccn1-c1ccccc1 +COCc1ccc(C(=O)Nc2ccc(CN3CCCC3=O)cc2)cc1 +CN(CC(=O)N1CCOCC1)C(=O)CC1CC2CCC1C2 +COC(=O)Cc1cn2cc(Br)cc(N)c2n1 +CC1Oc2ccccc2OC1C(=O)Nc1cccc(C(F)(F)F)c1 +CCC(C)NC(=O)CCCC(O)c1ccc(F)c(F)c1 +CCn1c(SCC(=O)NCC(C)C)nc2ccccc21 +CCc1nc(N)ncc1-c1nnnn1-c1ccccc1 +CCOCCNC(=O)NCCc1cccc(Cl)c1Cl +O=C(CCC(F)(F)F)Nc1cccn(Cc2ccc(F)cc2)c1=O +COc1ccc(OC)c(S(=O)(=O)N(C)Cc2ccccc2F)c1 +CCc1ccc(C2C(C(=O)OC)C(=O)CC(C)(O)C2C(=O)OC)cc1 +CC(C)(C)C(=O)N1CCC(C(=O)N2CCc3cc(F)ccc3C2)CC1 +Cc1nn2c(=O)cc(COC(=O)c3cccc(Cl)c3)nc2s1 +CC(C)(C)C(=O)N1CCC(Oc2cccnn2)CC1 +CC(C)(C)OC(=O)N1Cc2c(N)n[nH]c2C12CCC2 +Nc1cc(-c2cccc(F)c2)nn1Cc1ccccc1 +O=C(c1ccc(F)cc1F)N(Cc1cccs1)CC1CCCO1 +Cc1cnc(C(=O)OCC(=O)c2ccc(F)c(F)c2)cn1 +Cc1nn(Cc2cccnc2)c(=O)c2c1cnn2-c1ccccc1 +CCc1onc(C)c1NC(=O)CCSc1ccc(F)cc1 +Cc1ccc2cc(-c3nc(-c4ccncc4)no3)[nH]c2c1 +CC1CCCCN1C(=O)CSc1nc(=O)ccn1C1CC1 +O=C(NCc1ccc(Cl)cc1)c1ccc(F)cc1-n1cnnn1 +COc1ccc2oc(=O)c(C#N)c(N3CCC(C)CC3)c2c1 +Cc1ccc(OCC(=O)Nc2cnn(Cc3ccccc3)c2)cc1 +Nc1cnn(CC(O)c2ccc3c(c2)ncn3C2CC2)c1 +CCNC(=O)CCCC(=O)c1cc(F)ccc1F +Cc1cnc(N2CC(NC(=O)c3cnccn3)C3OCCCC32)nc1 +CC(O)CNc1ncnc2c1oc1nc3c(cc12)COC(C)(C)C3 +CC(=O)Nc1cccc(NCc2ccc(-n3nc(C)cc3C)cc2)c1C +CCC(C)NC(=O)COC(=O)c1ccc(C(F)(F)F)cc1 +COc1cc(C)c(C(=O)NC(C(N)=O)C(C)(C)C)cc1OC +O=C(Nc1cccnc1)c1nnc(N2CCCC2)c2ccccc12 +CCNC(=O)c1ccc(NC(=O)c2cnc3ccc(C)cn23)cc1 +O=C(NCc1csc2ccccc12)NCC1CCOC1 +O=c1c2cc(Cl)ccc2ncn1Cc1cccc(F)c1 +COC(=O)c1ccccc1NC(=O)c1csc(-c2ccoc2)n1 +CCOCCNC(=O)Nc1cc(NC(C)=O)ccc1Cl +Cc1occc1C(=O)NCc1ccnc(OC2CCOCC2)c1 +CC1CS(=O)(=O)N(c2cccc(C(=O)N3CCOCC3)c2)C1=O +Nc1c(C(=O)N2CCCCC2)sc2nc(-c3cccnc3)ccc12 +O=C(COc1cccc(Cl)c1)Nc1cccnc1 +N#Cc1ccc(N2CCCN(C(=O)c3cn4cccnc4n3)CC2)cc1 +O=C(c1ccc(F)cc1)N1CCC(O)(c2ccccn2)CC1 +N#CCCN1CCN(Cc2ccc3ccccc3c2)CC1 +CCNc1ncc(C(=O)NC2CCCCNC2=O)cn1 +CCN(Cc1noc(C)n1)C(=O)c1cccc(-n2cnnc2)c1 +O=C(CCOc1ccccc1F)Nc1ccc(C(=O)NC2CC2)cc1 +CCC(=O)Oc1ccc(C(=O)Nc2cc(OC)ccc2OC)cc1 +O=C(NCc1nc2ccccc2s1)Nc1cn[nH]c1 +CCOc1ccc(CC(=O)N2CCC(C(=O)N(C)C)CC2)cc1 +O=C(Cc1ccccc1)NCC(=O)Nc1ccncc1 +Nc1ccc2c(c1)OC(c1ccccc1Cl)CC2=O +N#Cc1cccc(S(=O)(=O)Nc2c(F)cccc2F)c1 +CC(NC(=O)Nc1ccccc1)C(=O)Nc1cccc(CO)c1 +CC1(C)OCC(COC(=O)c2cccn2C2CC2)O1 +CC(NC(=O)OC(C)(C)C)C(=O)NCCc1ccco1 +O=C(OCCCn1cccn1)c1scnc1C1CC1 +CCCc1noc(CCCC(=O)Nc2cc(C)on2)n1 +Cc1[nH]nc(C(=O)Nc2cccc(C(C)C)c2)c1N +CCN(CCO)C(=O)CCc1ccc(N2CCCC2)c(N)c1 +CC(C)N(C)C(=O)Cc1ccc(-n2cnnn2)cc1 +Cc1cc(NC(=O)c2ccc(C)s2)n(Cc2ccccc2)n1 +CCCc1noc(COc2ccc3c(c2)CCCC3=O)n1 +NC(=O)c1cc(Cl)ccc1OCCn1c(=O)oc2cccnc21 +CCOc1ccc(F)c(C(=O)N2CCN(C)C(=O)C2(C)C)c1F +O=C(Oc1ccc2c(c1)OCO2)c1ccc(-n2cncn2)cc1 +COc1ccc(C(O)CCC(=O)N(C)C)cc1F +CCOC(=O)c1cccc(NC(=O)C2CC(=O)N(CC3CC3)C2)c1 +CCCn1nc(C(=O)Nc2nc3ccccc3n2CCC)ccc1=O +Cc1cc(C)c2nc(C)cc(C(=O)NCc3ccccn3)c2c1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)NCCCc1cn[nH]c1C +COC(=O)N1CCN(C(=O)c2ccc(Br)c(F)c2)CC1 +CC(=O)Nc1nc2c(s1)CN(C(=O)NC(C)C)CC2 +CC(Cn1ccnc1)NS(=O)(=O)Cc1ccc(F)cc1 +O=C(NCc1ccc(F)cc1)c1cccnc1SCC(F)(F)F +CC(C)(C)C(=O)N1CCOc2ccc(NC(=O)c3ccoc3)cc21 +COc1ccccc1C(NC(=O)C1CCCC1)c1ccccn1 +Cc1ccc2c(c1)NCC(=O)N2CC(=O)N1CCCC1 +CC1CC(=O)c2cc(C(=O)NCCCc3ccco3)c(=O)[nH]c2C1 +Cc1cc(OCC(=O)N2CCN(CCC#N)CC2)ccc1Cl +COC(=O)c1cccc(C(=O)NCCc2csc(C)n2)c1 +N#Cc1ccc(NC(=O)c2ccccn2)c(C(F)(F)F)c1 +NC(=O)NCc1ccc(S(=O)(=O)C2CCCC2)cc1 +CC(=O)c1c(C)[nH]c(C(=O)NCCc2cccc(C)c2)c1C +Cc1cc(C)nc(C(C#N)C(=O)c2cnn(-c3ccc(F)cc3)n2)n1 +CCOc1ccccc1OCC(=O)NC(C)c1ccc(F)cc1F +N#CCCN(c1ccc2cc(N)ccc2n1)C1CC1 +O=C(NCC(O)c1ccc(F)cc1F)c1nccc2ccccc12 +CCC(C)NC(=O)C(C)Nc1cccc(OC)c1 +Cc1cc2c(c(Nc3ccc(F)cc3)n1)C(=O)OC2 +C#CCN1C(=O)c2ccccc2NC1c1ccc(OC)cc1OC +CCN(C(=O)NC(C)c1ccc(-n2ccnc2C)cc1)C1CC1 +Cc1nccn1-c1ncccc1NC(=O)CCOCC1CCCO1 +COC(=O)c1c(C)nn(CC(=O)N2CCCCC2C)c1C +CNC(=O)c1ccc(CN(c2cccc(C)c2)S(C)(=O)=O)cc1 +Cc1ccc(C(=O)CCCC(=O)N2CCCC2)cc1C +CC(C)C(=O)N1CCNC(=O)CC1c1ccccc1 +CSc1nccn1-c1cccc(C(=O)OCCc2cccnc2)c1 +CCN(Cc1cccc(F)c1)C(=O)CSc1nnc(C2CC2)n1C +Nc1ccc(SCC(=O)Nc2nc(-c3ccccc3)cs2)cc1 +CCCC(C)C(=O)N1CCCCC1CC(=O)OC +Cc1cncc(C(=O)N2CCOC3C(Oc4cccnc4)CCC32)c1 +CCN1CCn2c(nc3cc(NC(=O)c4ccccc4)ccc32)C1 +O=C(NCc1ccccc1)NCC(O)Cc1ccccc1 +O=C(c1nccnc1-c1nc2ccccc2s1)N1CCCC1 +CN(Cc1ccc(C#N)cc1)C(=O)NCC1CN2CCCCC2CO1 +CCOC(=O)c1sc(NC2CCCCC2)nc1C +CC(C)COc1ccc(C(C)(C)CNC(=O)c2n[nH]c(=O)[nH]2)cc1 +CCCC1CN(C(=O)c2c(C)nsc2NC)CCO1 +COc1ccc(CCC(=O)N2CCCC(C(N)=O)C2)cc1 +O=C1COc2cc(C(=O)NCc3ccoc3)ccc2N1 +O=C(Nc1ccc2c(c1)OCCO2)c1ccn(-c2ccccc2)n1 +CC(C)C(C)NC(=O)c1cccc(-n2cccc2)c1 +CCC(Oc1ccccc1C(C)C)C(=O)NCc1nc(C)sc1C +N#CC1(NC(=O)COc2ccc3ccc(=O)oc3c2)CCCCC1 +Cc1nc(C2CCCN(c3nccnc3C#N)C2)no1 +N#Cc1cccc(NCc2ccccc2OC(F)F)c1 +COCCCCCNC(=O)N1CCN(c2nccs2)CC1 +Nc1nccnc1C(=O)NCc1ccc2c(c1)OCO2 +Cc1ccc(Cl)cc1N1CC(C(=O)NCC(F)(F)F)CC1=O +CCOC(=O)N1CCN(CC(O)COc2ccc(C)cc2C)CC1 +CCC1CCC(CNC(=O)NCCNC(C)=O)CC1 +Cc1csc2ncc(C(=O)NCc3ccco3)c(=O)n12 +Cc1nc(C(=O)NCc2ccc(C#N)cc2)nn1-c1ccc(F)cc1 +Nn1c(SCc2ccc(F)cc2)nnc1-c1ccccn1 +Nc1c(C(=O)NCc2cccs2)nnn1Cc1ccccc1 +NC(=O)C1CN(C(=O)Nc2cc(F)ccc2Cl)CCO1 +CCOC(=O)c1cc(NC(=O)N2CCc3sccc3C2CC)c[nH]1 +O=C(NC1CCC1)c1ccc(C#Cc2cccc(F)c2)nc1 +C#CCOc1cc(F)ccc1NC(=O)NCc1ccncc1 +O=C1COc2ccc(NC(=O)c3c(F)cccc3Cl)cc2N1 +CC1CN(C(CNc2ccc(C#N)cn2)c2cccs2)CCO1 +CCN1CC(C(=O)NCc2ccc(CN3CCCC3=O)cc2)CC1=O +Cc1nnc(SC(C)C(=O)c2ccccc2)n1C +COCc1nc(NC(C)Cc2cc(C)n[nH]2)c2cnn(C)c2n1 +CN(C(=O)Cn1cc(Br)cn1)C1(C#N)CCCCC1 +O=C(NCC1CCCOC1c1ccccc1)c1ccc[nH]c1=O +Cc1cc(-c2cccnc2)c(C#N)c(N2CCOCC2)n1 +Cc1ccc(C(=O)NCCOc2ccccc2)s1 +O=C(c1cc(Cn2cnc3ccccc32)on1)N1CCOCC1 +N#CC1(C(=O)N2CCN(Cc3ccon3)CC2)CCC1 +COC(=O)C1CCN(C(=O)c2cc3c(s2)CCC(C)C3)CC1 +CC(C)c1csc(C(=O)Nc2ccccc2C(=O)N(C)C)n1 +Cc1ccc(S(=O)(=O)CC2CSc3ncnn32)cc1 +CC1(CNS(=O)(=O)c2ccc(S(N)(=O)=O)cc2)CCCC1 +Cc1ccccc1NC(=O)Cn1cnc(NC(=O)c2ccccc2)n1 +COc1ccc(Cl)c2c1[nH]c1nc(SCC(N)=O)nnc12 +CC(=O)N1CCC(Cc2ccc(-c3ccc(CO)cc3)nc2)CC1 +CC1(NC(=O)c2cc(-c3cccnc3)on2)Cc2ccccc2C1 +CN(C(=O)C1CC(=O)N(c2ccccc2Cl)C1)C1CC1 +Cn1c(N)c(C(=O)COC(=O)Cc2ccccc2)c(=O)n(C)c1=O +Nc1ccc2c(c1)OCC(Nc1ccc(F)c(F)c1)=N2 +CCC(CNC(=O)NCc1ccoc1)c1ccccc1 +Cc1nccn1-c1ccc(CNC(=O)c2ccc[nH]c2=O)cn1 +Cc1cccc(NC(=O)c2ccc3c(=O)n4c(nc3c2)CCCC4)n1 +CN(CCNC(=O)Nc1ccc(-n2cncn2)cc1)S(C)(=O)=O +Cc1cccc(C(=O)Nc2ccc(C(N)=O)cc2)c1 +CCCC(C)C(=O)N1CCC(C(N)=O)c2ccccc21 +CCOC(=O)NCCC(=O)N1CCN(c2cccc(C)c2C)CC1 +O=C(COC(=O)c1ccc2c(c1)OCCO2)c1ccccc1 +Cc1nc(C)c(C(=O)N(CCO)C2CCCCC2)s1 +O=C(Cc1ccc(O)cc1Cl)N1CCCC1c1ccncc1 +CCOc1cccc(C(O)CNCc2ccccn2)c1 +CC(C)c1c(C#N)nnn1CCOc1ccc(Cl)cc1 +COc1ccc(CNC(=O)c2cnn3ncccc23)c(OC)c1 +CS(=O)(=O)NCCCNC(=O)c1ccc2c(c1)OCCCO2 +COc1ccc(Cl)cc1NCCC(=O)N(C)Cc1cnn(C)c1 +CCNc1c(NS(=O)(=O)CC)c(=O)oc2ccccc12 +COC(=O)C1CCCC1C(=O)N1CCCC1c1cnn(C)c1C +COc1ccc(-c2nnc(SCC#N)n2C(C)C)cc1 +COc1ccccc1CNC(=O)c1ccc(N(C)C)nc1 +CC(C(=O)Nc1ccc(F)cc1)n1cnc2ccccc2c1=O +CCC(CCO)NC(=O)NCc1ccc(O)c(F)c1 +CC(C)Cc1cc(C(=O)NCC(O)c2ccc(F)cc2)n(C)n1 +Cc1nnc(COc2ccc3ccccc3c2Br)o1 +NC(=O)CCN1CCN(C(=O)CC2CCCCC2)CC1 +Cc1cccc(C)c1OCC(O)CSc1nnnn1C +CCCc1nn2c(N)c(C#N)nnc2c1-c1ccc(F)cc1 +CCN(C(=O)c1ccc(N(C)C)c(F)c1)c1ccc(OC)nc1 +c1ccc(COc2cccn3c(N4CCOCC4)cnc23)cc1 +O=C(NCCCOCC1CCOC1)c1cccc(F)c1 +O=C(NC1CCCC1)N1CCC(S(=O)(=O)c2ccccc2)CC1 +CCNC(=O)N1CCc2nc(-c3ccccc3)ncc2C1 +O=C(CCc1nc(-c2ccccn2)no1)N1CCc2ccccc2C1 +O=C(Nc1cnc2ccccc2c1)c1cc(Cl)c2c(c1)OCCO2 +CCNS(=O)(=O)c1ccc(NC(=O)c2ccccn2)cc1 +Cc1ccc(CCC(=O)Nc2ccc(Br)cc2)o1 +CCc1onc(C)c1NC(=O)Cc1csc(N2CCCNC2=O)n1 +Cc1cc(NC(=O)C2CC2)sc1C(=O)N(C)CC(O)C1CC1 +COc1ccc2cc(C(=O)N(C)Cc3cc(C(C)C)no3)n(C)c2c1 +CC(NC(=O)COc1ccc(Cl)cc1Cl)c1ccncc1 +CN(CC(N)=O)C(=O)Cn1cnc2ccccc2c1=O +CC(C)(C)C(O)CCNS(=O)(=O)c1ccc(F)c(F)c1 +CCCOC(=O)c1nnc2sc(-c3cccc(F)c3)nn12 +C=CCNc1nnc(SCC(=O)N2CCCCC2C)s1 +CCCN1CC2=C(C1=O)C(c1ccccc1C)NC(=O)N2 +CCN(CC)c1ncnc(Sc2ccc(C)cc2)c1N +CN(CC(=O)NC(Cc1ccccc1)C1CCCC1)S(C)(=O)=O +CC(=O)Nc1ccc(OC(=O)c2ccoc2C)cc1 +NC(=O)C1CCCN(C(=O)CNc2ccc(Cl)c(Cl)c2)C1 +Cc1cnc(C(C)CNC(=O)Nc2cnc(N(C)C)nc2)s1 +COc1ccc(CNc2nc(-c3ccccc3)no2)c(OC)c1 +Cc1nc[nH]c1C(=O)NCCOCc1ccc(Cl)cc1 +COC(=O)C(NC(=O)c1ccc2c(c1)CCCC2)C(C)C +CN(C)S(=O)(=O)c1cccc(NC(=O)C2CCC2)c1 +Cc1cc(C)n(Cc2ncc(-c3ccccc3)o2)n1 +CN(Cc1cccs1)S(=O)(=O)Cc1cccc(N)c1 +Cn1c2ccccc2n2c(SCc3cscn3)nnc12 +CC(=O)Nc1ccc(NC(C)C(=O)NCc2ccccc2F)cc1 +CCc1ccc2[nH]c(=O)c(CN(CCO)C(=O)c3ccco3)cc2c1 +O=C(c1cc(F)cc(F)c1)N1CCOc2ccccc21 +N#Cc1c(NC(=O)CCn2cnnn2)sc2c1CCCC2 +CC(c1ccncc1)N(C)C(=O)Cc1ccc(F)c(F)c1 +CCN(CC1CCCO1)C(=O)c1cc(C)nc2c(C)cccc12 +Cc1cccc(CNC(=O)c2cc(Cl)ccc2OC(C)C)n1 +CNC(=O)C1CCCN1C(=O)c1cc(-c2ccc(F)cc2)c(C)s1 +CC(C)(C)c1nnc(SCC2CCCC2)n1N +Cc1cc(-n2c(C)cc(C(=O)NCC(C)(O)c3ccco3)c2C)no1 +Cc1cc2c(cc1C)C(c1cnccc1Cl)NCC2 +CCOC(=O)CCC(=O)c1ccccc1SC +Cc1nc(C)c(C(=O)NCc2ccc(OCC(C)C)cc2)s1 +CCc1onc(C)c1NC(=O)NCC1(c2ccccc2)CC1 +CCN(CC)S(=O)(=O)NC(c1ccc(F)cc1)C(C)C +CCOc1ccc(C(=O)NC2c3ccccc3CC2O)cc1OCC +O=C(NCc1noc(-c2ccc(-n3ccnn3)cc2)n1)c1ccccc1 +CN(Cc1c(C(=O)N2CCCC2)nc2ccccn12)CC1CCCO1 +Cc1ccc2c(C)cc(SCC(=O)NC3CC3)nc2c1 +O=C(NCC1(C(O)c2ccccc2)CC1)c1cnoc1C1CC1 +O=C1NCCCCC1Sc1nc2c(n1-c1ccccc1)CCCC2 +CCOC(=O)C1C(=O)NCC1c1cc(OC)c2c(c1)OCO2 +COc1nc(C)nc2c1sc1nc3c(cc12)COC(C)(C)C3 +Cc1ccn2c(=NC(=O)c3ccc(-n4cccc4)c(F)c3)[nH]nc2c1 +Cc1nc2c(NC3CCN(C(=O)c4cccs4)CC3)cccn2n1 +COC(=O)c1ccc(CSc2nnc(-c3cccnc3)n2C)cc1 +COc1ccc2ccn(Cc3ccc(F)c4cccnc34)c(=O)c2c1 +O=C(Nc1ccc(F)cc1OC(F)F)N1CCOCC1C1CC1 +CC1CC(C)CN(S(=O)(=O)N(CCC#N)CCC(F)(F)F)C1 +Cc1nnc(SCC(=O)Nc2ccc(Cl)cn2)n1C +COc1ccc2cc(NC(=O)COc3ccccc3)cnc2c1 +O=C(NCc1nc(C2CC2)no1)c1ccccc1O +CC(C)(CNC(=O)N1CCC(Cn2ccnn2)CC1)c1ccncc1 +CCCn1cc(NC(=O)CCCOC)ccc1=O +CCc1nc(CSc2n[nH]c(=O)n2CC2CCCO2)no1 +CS(=O)(=O)NCCCNC(=O)c1ccccn1 +CCOc1ccc(-c2cnnn2Cc2ccccc2C#N)cc1 +CN1CCN(S(=O)(=O)c2ccc3c(c2)CCN3C(=O)C2CC2)CC1 +Nc1ccc(SCC(=O)Nc2ccccc2Br)nc1 +COc1ccccc1NC(=O)NC1CCN(c2nccs2)CC1 +NC(=O)C1CCCN1C(=O)C1CC(=O)N(c2ccc(F)cc2F)C1 +CC(Sc1nnc(N)[nH]1)C(=O)Nc1ccc(Cl)cc1F +CC(C)CNC(=O)C(C)S(=O)(=O)c1nnc(N2CCCC2)s1 +Cc1ccc(Cn2nccc2NC(=O)c2ccccc2F)o1 +CC(C)NC(=O)CCNCc1ccccc1C(F)(F)F +C=CCNC(=O)C1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 +CC(C)NC(=O)c1cc(N2CCCC2)n2nccc2n1 +Cc1ccoc1C(=O)N1CCC(NC(=O)c2ccc[nH]2)CC1 +CCOc1ccccc1CC(C#N)C(=O)N1CCCC1 +CC(C#N)CN(C)C(=O)Nc1ccc(Cl)cc1 +CNC(=O)C1(NC(=O)c2ccc(C)s2)CCCCC1 +CC(=O)Nc1cccc(C(=O)NC2(C#N)CCCCC2)c1 +Cc1ccc(C)c(CC(=O)Nc2nnc(-c3ccn(C)n3)o2)c1 +C#CCn1cnc2c(nnn2-c2cccc(F)c2)c1=O +Nc1cccc(-c2nnc(C3Cc4ccccc4N3)o2)c1 +NC(=O)CCCNC(=O)C1CCCN(C(=O)Cc2ccc(F)cc2)C1 +CN(C(=O)c1cnc(C2CCCO2)s1)c1ccc(F)c(F)c1 +Cn1nccc1CNC(=O)Nc1cc(F)ccc1Cl +CCOc1ccccc1CSc1nc(N)cc(N)n1 +O=C(NCCS(=O)(=O)c1ccc(F)cc1)c1ccn2nnnc2c1 +CCS(=O)(=O)NCc1nnnn1C1CCCCC1 +CC(C)(C)c1cnc(CN2CCN(C(=O)c3ccsc3)CC2)o1 +O=C(OCn1nnc2ccccc2c1=O)c1cc(F)cc(F)c1 +CC1(C)CN(C(=O)CNC(=O)c2ccsc2)CCO1 +CCN(CC)C(=O)c1cc2c(=O)n3ccccc3nc2s1 +CCOc1ccccc1C(=O)NCCCC(=O)N1CCCC(C)C1 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+NC(=O)c1ccc(NCC(=O)N2CC(=O)Nc3ccccc32)cc1 +CC(=O)Nc1ccc(-c2nn3c(C)nnc3s2)cc1C +NC(=O)N1CCC(NC(=O)c2cccs2)CC1 +Cc1ocnc1C(=O)N1CCC(c2ccc(C(F)(F)F)cc2)CC1 +Cc1n[nH]c(C)c1S(=O)(=O)N(CCCO)C(C)C +Cc1ccc(C(=O)CCC(=O)n2ncc(C#N)c2N)cc1 +COc1cc(NC(=O)c2ccc3c(c2)OCO3)ccc1-n1cnnn1 +CC(Sc1nnnn1C)C(=O)Nc1ccccc1-c1ccccc1 +CCN(Cc1cnc2ccccn12)C(=O)c1cc2ccccc2o1 +O=C(NCCSc1cccc(F)c1)OCC(F)(F)F +O=C(c1ccc(Cl)cc1-n1cnnn1)N1CCc2ccccc2C1 +C=CCc1cc(C(=O)NC(C)c2ccccn2)cc(OC)c1OC +CCn1nc(-c2ccc(F)c(C)c2)cc(C(C)=O)c1=O +O=C(CNC(=O)C1CCCCC1)OCc1ccc(-n2cccn2)cc1 +COc1cc(C(=O)NCc2ccc(Cn3cccn3)cc2)ccc1C +COC(C)(C)c1noc(-c2ccc(=O)n(Cc3ccccc3)n2)n1 +O=C(c1ccoc1)N1CCC2(CC1)CN(c1ncccn1)CCO2 +COc1ccc(NC(=O)CCn2c(=O)c(C)nc3ccccc32)cc1 +COCC(NC(=O)N1CCCCC1c1cn[nH]c1)C1CC1 +Cc1ccccc1N1CC(C(=O)NCc2ccccn2)CC1=O +COc1ccc(C(=O)NCCNC(=O)Nc2c[nH]c(=O)cc2C)cc1 +CCOC(=O)C1CCN(C(=O)CSc2ccc(F)cc2)CC1 +Cc1cccc(CNC(=O)NC2CCN(C(=O)c3ccoc3)CC2)c1 +COc1ccc(NC(=O)Cc2cccc(Cl)c2)cc1OC +Nc1ccc(-c2csc(CC(=O)NC3CCCCC3)n2)cc1 +CC1C(=O)NCCN1C(=O)c1ccc(S(=O)(=O)C(C)C)cc1 +Cc1csc(NC(=O)C2CCN(C(=O)NC3CC3)CC2)n1 +Cc1noc(COc2ccc(NC(=O)Cc3ccccc3C)cc2)n1 +O=C(Cn1nnc2ccccc2c1=O)NCc1ccc2c(c1)OCO2 +Cn1ccsc1=NC(=O)c1cnc(-c2ccccc2)nc1 +COC(=O)Cc1cc(=O)n(-c2cccc(Cl)c2)[nH]1 +COc1cc(C)c(S(=O)(=O)N2CCN(C(C)=O)CC2)c(C)c1 +CNC(=O)C1(NC(=O)c2ccc(CCC(C)(C)O)cc2)CCCCC1 +CC(NS(C)(=O)=O)C(=O)NCc1ccccc1F +CC(=O)Nc1ccc(C(=O)OC(C)C(N)=O)cc1 +COCCOc1ccc(NC(=O)C2CCOC2)cc1Cl +COc1cc2c(cc1OC)C1(CC1)CNC2c1ccncc1 +Cc1ccc(-c2ccc(CNc3ncn[nH]3)o2)cc1Cl +CNC(=O)c1cc(NC(=O)c2cn3cccnc3n2)ccc1F +Cc1ccsc1CNC(=O)c1cccc(N(C)C)c1 +CCC(=O)Oc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1 +COc1ccc(-c2nc(CC(N)=O)nn2-c2ccc3c(c2)CCC3)o1 +O=C(C1CCCCC1)N1CCC(OCc2ccccc2)CC1 +C=CCNC(=O)N1CCC(N2CCNC2=O)CC1 +Cc1c(CNc2cccc(C(F)(F)F)c2)cnn1C +Cc1cc(C)cc(NC(=O)NCc2ccc(C(=O)N(C)C)cc2)c1 +Cc1nn(CC(O)C(F)(F)F)c(C)c1S(=O)(=O)NC(C)(C)C +COc1cc2nc(NC(=O)Cc3c(C)noc3C)sc2cc1OC +COc1ccnc(N2CCC(C3CCCCCN3C(C)=O)CC2)n1 +CCOC(=O)CC(C)CNC(=O)c1ccc(C)nc1 +CS(=O)(=O)c1cccc(OC(=O)C2CCOc3ccccc32)c1 +Cc1ccc(C(C)NC(=O)c2ccc(C)c(S(C)(=O)=O)c2)o1 +CCC1CN(c2ncccc2C#N)CCC(=O)N1Cc1ccccc1 +CCCCn1c(SCC(=O)N2CC(C)CC(C)C2)n[nH]c1=O +Cc1ccc(-c2cc(C(=O)N3CCCC3)c3c(C)nn(C)c3n2)cc1 +Nc1cccc(C(O)CN2CCc3ccccc3C2)c1 +Cc1ccccc1OCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CC(=O)NCCNC(=O)Cc1coc2cc(C)c(C)cc12 +O=C(Cc1cn2c(nc1=O)SCC2)Nc1cccc(F)c1 +O=C(Nc1nc(-c2ccccn2)cs1)C1CC1c1ccco1 +N#CC(c1ccccc1)N1CCN(CC(=O)NCc2ccco2)CC1 +CCCCS(=O)(=O)NCC(=O)N1CCc2sccc2C1CC +CC(Sc1nc(N)cc(=O)[nH]1)c1nnc(-c2cccc(Cl)c2)o1 +CNC(=O)c1ccsc1NC(=O)c1cnn(-c2ccccc2)c1C +O=C(CSc1ccccn1)N1CCN(c2ccccc2)CC1 +CCC(C)n1ncc(C(=O)Nc2cccc3cn[nH]c23)c1C1CC1 +COc1ccc(NC(=O)c2ccc(Cn3cccn3)o2)cn1 +COCc1cc(C(=O)NCc2cccc(C)c2)ccc1F +Cc1cccc(OCC(O)CNC(=O)c2n[nH]c(=O)[nH]2)c1 +CC(c1ccncc1)N(C)S(=O)(=O)c1ccc(Cl)cc1 +N#CCCN(C1CC1)S(=O)(=O)c1cccc(Cl)c1 +O=C(NCc1ccncc1)c1ccc(OCc2ccccc2)cc1 +O=C(NCCc1ccc2c(c1)OCO2)NC1CCCC1 +COC(C)C(=O)N1CCN(Cc2ccc(Br)cn2)CC1 +CC(C)Oc1ccc(NC(=O)Nc2ccccn2)cc1 +COc1ccccc1CN(C)C(=O)CNc1cccc(C)c1 +COc1ccc(C)cc1NC(=O)C(CC(C)C)N1CCCCC1=O +Cc1ccn2cc(C(=O)N3CCN(c4ccccc4C)CC3)nc2c1 +Cc1ccc(S(=O)(=O)NCCc2ccc3c(c2)OCCO3)cc1C +CC(=O)c1c[nH]c(C(=O)N(CCCO)C(C)C)c1 +Cc1ncccc1C(=O)N1CCC(c2nc3ccccc3cc2N)CC1 +CC(C)CCNC(=O)c1ccc(-c2ccncc2)nc1N +COc1ccc(NC(=O)CN(C)C(=O)C2CCCO2)cc1 +CC(C)Oc1ccc2nc3c(cc2c1)c(N)nn3C +Cc1ccc(CCC(=O)NCCc2nc(-c3cccnc3)n[nH]2)o1 +CCCC(=O)Nc1cccc(C(=O)Nc2ncccn2)c1 +c1ccc(CNc2cccc(-c3cnco3)c2)cc1 +CC(=O)C(C)OC(=O)CSc1cnc2ccccc2n1 +CCOc1ccc(CC(=O)NCc2cnn3ccccc23)cc1 +COc1cc(CNC(=O)c2cnns2)ccc1OCC(N)=O +COc1ccccc1C#CCNC(=O)c1c(F)cccc1F +CCN(Cc1ccc2c(c1)OCCO2)C(=O)c1c(F)cccc1F +CNC(=O)C1COC2CCN(S(=O)(=O)c3ccccc3)CC2C1 +CCOC(=O)CNC(=O)c1ccccc1SC(C)C +COc1ccc2ncnc(NCCCCCO)c2c1 +O=C(Nc1nncc(-c2ccccc2)n1)OCC(F)(F)F +CCOc1cc(F)ccc1NC(=O)CC(NC(C)=O)c1ccccc1 +Cc1noc(CCC(=O)NCCc2ccc(C(C)(C)C)cc2)n1 +Cc1nc(C)c(CC(=O)OCc2nc(-c3ccccc3)no2)c(=O)[nH]1 +Cc1cc(CNC(=O)NCc2ccc(F)cc2)no1 +NC(=O)C1CCN(c2nc(-c3ccncc3)nc3ccccc23)CC1 +Cc1ccc(NC(=O)Cn2cnc(C)c(C)c2=O)c(F)c1 +CCOC(=O)C1=C(CC)N(C)C(=O)NC1c1cccnc1 +CC(C)(CO)NC(=O)C1CCOc2ccccc2C1 +NC(=O)NCC(=O)NCc1ccc(OCc2cccnc2)cc1 +CC(C)c1nnc2n1CCN(CCCOc1ccc3c(c1)OCO3)C2 +Cc1ccc(C(=O)CNC(=O)Cc2ccc(F)cc2)cc1C +CCCn1c(=O)c2sccc2n(CC(=O)NC(C)CC)c1=O +O=C1CN(c2ccccc2NC(=O)c2c(F)cccc2Cl)CCN1 +O=C1CCCC2(CN(Cc3ccccc3)CC2c2ccccc2F)N1 +O=C(c1cccc(CO)n1)N1CCCC(COc2ccccc2F)C1 +CCc1onc(C)c1NC(=O)c1nnn(-c2ccccc2Cl)c1C +COc1ccc(CNc2nccs2)cc1OC +CCOC(=O)CCc1c(C(F)(F)F)nc(N)[nH]c1=O +CC1CCN(C(=O)CNc2cccc3c2CCCC3)CC1 +O=C(CNC(=O)c1c[nH]c2ccccc2c1=O)NC1CCCC1 +O=C(NCc1csc(C2CC2)n1)c1cc(Cl)ccc1Cl +COc1cc2c(cc1OC)C1(C=C2)CCN(C(=O)OC(C)(C)C)CC1 +Cc1ccc(OC(C)C(=O)NCCc2ccccn2)cc1 +CC(OC(=O)c1cc2ccccc2s1)C(=O)NCc1ccco1 +CC(C)n1cnnc1CN(C)C(=O)COCc1ccccc1 +CCc1nnsc1C(=O)NCCOc1ccc(F)cc1 +COCCNC(=O)C1CCCN(c2ccc3nncn3n2)C1 +N#CCCCSc1nccn1Cc1ccccn1 +N#Cc1c(-c2ccc(F)cc2)c2c([nH]c1=O)CCCC2 +COc1ccccc1C(C)(C)NC(=O)NCc1cccnc1OC +CNC(=O)c1ccc(S(=O)(=O)NC(c2ccccc2)C2CC2)cc1 +COc1ccc(CCC(=O)N2CCC(C(N)=O)C2)cc1OC +Cn1cc(NC(=O)Cc2ccccc2F)cc(Br)c1=O +Cc1nc(C)n(C2CCCN(C(=O)c3cnns3)C2)n1 +Cn1ncc2c1CCCC2NC(=O)NCCOc1ccc(Cl)cn1 +CCOc1ccc(S(=O)(=O)N(C)c2ccccc2)cc1 +CCNC(=O)N1CCN(CC(=O)Nc2cccc3ccccc23)CC1 +CNS(=O)(=O)c1ccc(NC(=O)c2cc3ccccn3c2)cc1 +Cc1ccc2[nH]c3c(=O)n(Cc4nc(C(C)C)no4)cnc3c2c1 +CN(Cc1ccccc1)CC(O)c1ccc(F)cc1 +CCn1c(C2CCN(C(=O)c3cccnc3NC)CC2)n[nH]c1=O +COc1cccc(-c2ccc(C(C)(C)O)c(=O)n2C(C)C)c1 +Cn1cc(CC(=O)Nc2ccc(Oc3ccc(Cl)cn3)cc2)cn1 +CCCC1CCC(NC(=O)Cn2cnc3ccccc3c2=O)CC1 +CC(C)OC1CCC2C1OCCN2C(=O)c1nn(C)c2ccccc12 +COc1cccc(C(=O)CC2C(=O)Nc3ccccc32)c1 +N#Cc1cnc(NC(=O)Cn2cnc3ccccc3c2=O)s1 +CCOC(=O)CCc1c(C)[nH]n(-c2nc3ccccc3[nH]2)c1=O +CN(CCCn1cccn1)C(=O)C1CCN(C(=O)C2CCCC2)CC1 +Cn1ccc(NC(=O)c2ccc(Br)cc2F)n1 +CC(=O)NC(C)CCc1ccc(-c2csc(C3CC3)n2)cc1 +CCCC(=O)N1CCc2ccc(C(O)C(C)C)cc2C1 +COc1ccccc1NC(=O)CCn1cnc2c(cnn2C)c1=O +CC(C)c1nc(-c2cccnc2)cc(N2CCC(=O)CC2)n1 +N#Cc1ncn(CC(=O)Nc2cccc(Oc3ccccc3)c2)n1 +CCOC(=O)C(O)Cc1nnc(-c2ccncc2)n1C +Cc1csc(NC(=O)Cc2csc(-c3ccccc3)n2)n1 +Cc1cccc(NC(=O)c2snc(C#N)c2N)c1C +O=C(COC(=O)c1cccc(O)c1)Nc1ccc(Cl)cc1 +COc1ccc(S(=O)(=O)c2cnc3sccn3c2=O)cc1 +CS(=O)(=O)N1CCCN(C(=O)c2ccc3ccccc3c2O)CC1 +O=C(NCc1nnc2n1CCC2)c1ccc(F)cc1Br +CC(O)CNC(=O)C(NC(=O)c1cccs1)C(C)C +Cc1ccc(S(=O)(=O)Nc2ccc(C#N)cc2)cc1C +CCN1CCN(C2CCN(c3nc4ccccc4o3)CC2)C1=O +COCC(C)N(C)C(=O)c1ccc(C#CCO)s1 +CC(C)(CNC(=O)C1CCCN1C(=O)C1CC1)c1cccc(Cl)c1 +CC1COC(CO)CN1c1ncnc2ccc(Br)cc12 +Cc1ccccc1NC(=O)Nc1ncc(C#N)s1 +COCc1nc(C(=O)NCCOc2cccnc2)cs1 +Cc1cc(C)cc(C2(C(=O)NCC(C)CN3CCCC3=O)CC2)c1 +Cc1ccc(C(c2oc(C)cc(=O)c2O)c2oc(C)cc(=O)c2O)o1 +CCCn1ccc2cc(NC(=O)COc3cc(C)on3)ccc21 +N#Cc1ncn(CC(=O)Nc2nnc(-c3ccccc3)o2)n1 +Nc1ccc(Cl)c(C(=O)Nc2cccc3cccnc23)c1 +CC(CN1CCOCC1)NC(=O)c1ccc(=O)n(-c2ccccc2)n1 +COc1cc(F)c(S(=O)(=O)N2CCCC(C(N)=O)C2)cc1OC +COCCOc1ncccc1NC(=O)NCc1ncc[nH]1 +C=CCNC(=O)Nc1ccc(OCc2cccnc2)cc1 +CC(C)C(NCc1nnnn1C(C)C)c1nc(-c2ccncc2)no1 +Nc1nncn1C(=O)c1occc1Br +CC1CCCC(C)N1C(=O)Nc1cccc(F)c1 +CN(Cc1ccco1)C(=O)Cn1cnc2c(oc3ccccc32)c1=O +CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2ccccc2O)CC1 +O=C(NS(=O)(=O)N1CCc2ccccc2C1)c1ccco1 +Cn1cc(NC(=O)CCCn2cncn2)cc(Br)c1=O +CCCc1c(C(=O)NC2CC2)cnn1-c1ccccc1Cl +Cc1ccc(C(C)NC(=O)Nc2ccc(N3CCCC3=O)cc2)cc1 +Cc1ccc(-n2cnc(C(=O)Nc3cccc(F)c3)n2)cc1 +CC(NC(=O)N(C)Cc1ccccc1Br)c1ccncc1 +Cc1nsc(NCc2ccccc2OCCN2CCOCC2)n1 +COc1ccc(NC(=O)NCC2CCCC2)cc1OC +CNC(=O)CCCC(O)c1ccc(CC(C)C)cc1 +CCOc1ccccc1NC(=O)c1nn(-c2ccccc2)cc1OC +CCC1C(=O)NCCN1C(=O)COCCc1ccccc1 +O=C(NCc1cn2ccsc2n1)N(Cc1cccs1)C1CC1 +CS(=O)(=O)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 +NS(=O)(=O)c1ccc(NC(=O)N2CCc3sccc3C2)cc1 +Cc1ccc(NS(=O)(=O)c2ccc(S(N)(=O)=O)cc2)cc1C +CCN(CC)S(=O)(=O)N1CCCC(c2nc3ccccc3o2)C1 +COC(=O)Nc1sc(C)nc1-c1cccs1 +CC(C)CC(NC(=O)CSc1ncn[nH]1)C(=O)N(C)C +CCCc1nn(CCc2ccccn2)c(N)c1CC +C#CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1 +CC(=O)C(C)(C)c1ccc(S(=O)(=O)C(C)C)cc1 +O=C(NCc1ccc(F)cc1)NC1CCCCC1 +O=C(NCCc1noc(-c2ccccc2)n1)c1ccc2nccn2c1 +COc1c2c(cc3c1C(CC(=O)C(C)C)N(C)CC3)OCO2 +CCOc1ccc(CC(=O)N2CCCC2C(=O)NC2CC2)cc1 +Cc1cccc(CN2CCN(C(=O)Cc3c(C)noc3C)CC2)c1C +Nc1cnc2nc(COc3ccc(Cl)cc3)oc2c1 +Cc1cccc(CCNC(=O)c2ccc(N3CCOC3=O)cc2)c1 +COc1cc(F)cc(CNC(=O)Nc2ccc(S(C)=O)cc2)c1 +O=C(Nc1cccc(Br)c1)c1cc(-c2cccnc2)on1 +Nc1nccc(C2CCCN2C(=O)c2cccnc2)n1 +CC(C)n1c(C2CCCO2)nc2ccc(Cl)cc21 +CCC(C)OC(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C +CCOC(=O)c1cc2c(=O)[nH]c(N3CCCC3)nc2nc1C +NC(=O)C1CCN(C(=O)c2cc3ccccc3cc2O)CC1 +CCOC(=O)c1csc2nnc(-c3ccccc3)n12 +Cc1ccc(Cl)cc1NCc1nc(C(F)(F)F)cc(=O)[nH]1 +CC(=O)N(C)c1ccc(NC(=O)N(C)CCOCC2CC2)cc1 +COc1cccn(CC(=O)N2CC(n3nc(C)cc3C)C2)c1=O +COc1cccc(C(=O)NCCOc2ccc(-c3ccccc3)nn2)c1 +NS(=O)(=O)c1cccc(C(=O)NCCCN2CCCC2=O)c1 +C=CCN1C(=O)C(Cc2cccc(OC)c2)Oc2ccc(N)cc21 +CCC1CCCC(NC(=O)c2ccc(OCC(N)=O)c(OC)c2)C1 +Cc1ccccc1C1CC1C(=O)OCCOC(C)C +COc1ncccc1CNS(=O)(=O)c1ccc(C)cc1 +O=C1CC(c2cc(F)ccc2F)c2cnn(C3CCCC3)c2N1 +N#Cc1cc(-c2ccc(F)cc2)nc(N2CCOCC2)n1 +O=C(NCc1cn(-c2ccccc2)nn1)c1n[nH]c(=O)c2ccccc12 +COc1ccc(C(=O)Nc2cccc(C(=O)NC(C)C)c2)cc1 +COC(=O)N1CCCC(C(=O)OCc2coc(-c3ccccc3)n2)C1 +CCN(CC1COc2ccccc2O1)C(=O)c1ccc(=O)n(C)c1 +COC(=O)C1CCN(C(=O)c2cc(OC)ccn2)c2ccccc21 +Cc1ccc2c(c1)S(=O)(=O)N=C(NCc1cccnc1)N2 +Cc1cccc(OCC(=O)N2CCN(Cc3ccccc3F)CC2)c1 +OC(Cc1ccc(Cl)cc1)c1ccc2c(c1)OCO2 +O=C(Cc1ccccc1)NCCC(=O)OC1CCCCCC1 +COc1cccc(CC(=O)Nc2ccc(-c3ncc[nH]3)cc2)c1 +CCC(Oc1ccc(C)cc1)C(=O)Nc1nccs1 +CC(C)OCCOC(C)C(=O)Nc1cccc(N)c1 +FC(F)Oc1cccc2c1CCNC2CC1CC1 +O=C(NC1CCCC1)C1CCCN(C(=O)c2cc3cccn3cn2)C1 +CC(C)(C)CC(=O)NCC#Cc1ccc(C(N)=O)cc1 +Nc1ccc(-c2cccc(-n3cccn3)c2F)cc1 +Cc1occc1CNC(=O)CCNC(=O)N(C)Cc1ccccc1 +CC(C)CC(C)NCc1nc2ccccc2c(=O)[nH]1 +CCCC1(CNC(=O)NCCc2ccccn2)CC1 +CN(CC1CC1)C(=O)NCc1cccc(NC(=O)C2CCC2)c1 +Cn1cc(CCNS(=O)(=O)c2cc(F)cc(F)c2)cn1 +COc1ccccc1S(=O)(=O)NCCC(C)C +O=C(OCc1ccc(Cl)cc1)c1cc(C2CC2)[nH]n1 +Cc1cccc(C(=O)OCC(=O)NC(C)(C)C)c1N +CN(C(=O)COc1ccccc1N)C1CCCCC1 +Cc1ccc(Cl)c(OC(=O)Cn2c(=O)[nH]c3ccccc3c2=O)c1 +CC(=O)c1cccc(NS(=O)(=O)c2ccccc2O)c1 +O=C(CO)CCOc1ccc(Br)cc1 +Cc1cc(NC(=O)CN(C)c2c(F)cccc2F)on1 +Cc1cc(C)n(CCC(=O)NCCCn2cccn2)n1 +Cc1cc(N(C)C)cc(C)c1NC(=O)c1cccc(-c2ccoc2)c1 +CCOC(CC)C(=O)NCc1ccc2cc(OC)ccc2c1 +COc1cc(OC)cc(C(=O)Nc2nnc(C3CCCCC3)o2)c1 +CC(C)CNC(=O)Cn1nc(C#N)cc1-c1ccccc1 +COc1cc(-c2nc(-c3ccc(C#N)cn3)no2)ccc1C +OC(CSc1ccccn1)c1ccccc1Cl +CN(CCc1ccccc1Cl)C(=O)CCCO +COCCN1CCC2(CN(C(=O)c3ccc[nH]3)CC2C)C1=O +O=C(NCc1cccc2ccccc12)c1ccc(Cn2ccnc2)cc1 +Cc1ccc(NC(=O)C2CCC2)c(C)c1S(=O)(=O)NC1CC1 +Cc1ccncc1NC(=O)N1CCN(C(=O)CCC2CCCC2)CC1 +C=CCCCN(C)S(=O)(=O)c1cc(F)ccc1Cl +CC1(C)CN(CC(=O)N(Cc2ccco2)c2ccccc2)CCO1 +COCC(NC(=O)c1ccnc(N(C)C)c1)C(N)=O +CC(C(=O)NCc1ccccc1)S(=O)(=O)c1ccccc1 +Cn1ncc2c(SCC(=O)NCCc3ccccc3)ncnc21 +Cc1nc2c3c4c(sc3ncn2n1)CN(C)CC4 +CCOC(=O)c1csc(CNC(=O)c2cnc3ccc(C)cn23)n1 +COc1cc(OC)c(OC)cc1CNc1ncnc2ccsc12 +COc1ccccc1C(NC(=O)C1CCC1)c1nccn1C +CN(CC(=O)Nc1cccc(F)c1)C(=O)CN1CCCCCC1=O +CC(C)Cc1nnc(NC(=O)CN2CCCCC2=O)s1 +O=C(N(Cc1ccsc1)Cc1ccco1)C1(c2cccs2)CC1 +Cc1ccc(-n2cc(C(=O)N(C)Cc3ccccn3)nn2)cc1 +COc1ccc(SCC(=O)Nc2ccc3sc(C)nc3c2)cc1 +CCCC(=O)Nc1nnc(-c2ccc(OC)c(OC)c2)s1 +CC(C)n1nccc1NC(=O)C1CCN(C(=O)C2CC2)CC1 +CC(NC(=O)c1cc(F)ccc1Br)c1ccncc1 +C=CCNC(=O)c1ccc(NC(=O)C2(C#N)CCCC2)cc1 +CN(C)c1nc(-c2ccc(C(N)=O)c(Cl)c2)n[nH]1 +CC(C(=O)N1CCN(CC(O)c2ccccc2)CC1)n1cccn1 +COCc1cc(N2CCC(=O)CC2)nc(-c2cccc(Cl)c2)n1 +Cc1ccc(C(=O)CN2CCN(c3ccccc3F)CC2)cc1N +CC(C)Cn1c(N)nc2c(=O)n(C)c(=O)n(C)c21 +COc1cccc(OC)c1C(=O)Nc1cccc(-c2noc(C)n2)c1 +CC(C)C1Oc2cc(N)ccc2N(Cc2cccc(Cl)c2)C1=O +Nc1cc(Cl)cc2c1OC(c1cccs1)CC2=O +NS(=O)(=O)c1cnn(CC(=O)Nc2ccc(F)c(F)c2)c1 +COC(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +COc1ccc(-n2ccc(C(=O)NCc3cccnc3OC)n2)cc1 +Nc1cc(F)ccc1NC(=O)c1ccc(F)cc1Cl +O=C(Nc1cc(Cl)cc(Cl)c1)N1CC2CCC(C1)C2O +Cc1cc(C(=O)N2CC(C)CC(C)C2)ccc1N1CCNC1=O +CN(Cc1ccccc1)C(=O)CCNc1ccccc1 +Cc1ccsc1C(=O)N1CCN(C(C)c2cccnc2)CC1 +CN(C)C=Cc1cc(C#N)c(C#N)cc1Br +CC(C)c1nc(C2CCCN(c3ncnc4sccc34)C2)no1 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)OCc1ccc(F)cc1 +Cc1ccn(-c2ccccc2NC(=O)NCc2nc(C)sc2C)n1 +CNC(=O)c1cccc(OC(=O)c2cccn2Cc2ccccc2)c1 +NC(=O)C1CCN(C(=O)Cc2ccc(F)c(F)c2)C1 +C#CCN1CCC(C(=O)N2CC(=O)Nc3ccccc32)CC1 +COc1ccc(NC(=O)C(C)On2nnc3ccc(Cl)cc32)cc1 +Cc1cnccc1CCNC(=O)Nc1cccc(N2CCCCC2)c1 +O=C(CSc1nc2ccccc2o1)NCCc1ccccc1 +CC(C)Cc1nc(C(=O)Nc2cc[nH]n2)cs1 +O=C(COC1CCCCC1)NCc1cccc(O)c1 +CN(C(=O)c1cnn(-c2ccccc2)c1)c1ccccc1 +O=C(NCc1cccnc1)NC1CCCC1Oc1ccccc1 +CCOc1ccc(Cl)c(C(=O)NC(C)(C)CC)n1 +NC(=O)c1c[nH]c(C(=O)N2CCC(Cc3cccc(F)c3)CC2)c1 +COc1cc(C)c(C(=O)NCCN(C)c2ccccc2)cc1OC +CCc1cc(N(C)Cc2nnc3ccccn23)nc(-c2ccncc2)n1 +O=C(Cc1cc2c(cc1CO)OCO2)NCc1ccccc1 +Cc1cc(NC(=O)CCOCC2CCCO2)ccc1Br +Cc1nc(C)c(C(=O)N2CC3CCC2CN(c2ncccn2)C3)o1 +CN(C)c1nc(CNC(=O)NCCc2c(F)cccc2F)cs1 +Nc1ccc(Cl)cc1-c1nnc(C2CCCC2)o1 +Cc1nn(C)c(=O)c(C(=O)Nc2nc(-c3cccs3)cs2)c1C +COc1cccc2cc(C(=O)NCCn3ncccc3=O)oc12 +O=S1(=O)CCCN1c1cccc2c1CCCN2 +CCc1nnc(NC(=O)N2CCC(Cc3ccccc3)CC2)s1 +CCn1c(SCC(=O)Nc2nccs2)nc2ccccc2c1=O +Cc1cscc1C(=O)Oc1ccc2cn[nH]c2c1 +CN(Cc1nc(-c2ccccc2)no1)S(=O)(=O)c1ccccc1 +CC(C)(NC(=O)c1ccn(-c2cccc(Cl)c2)n1)C(N)=O +CC(C)C(=O)N1CCCC1C(=O)Oc1cccc(F)c1 +CCOC(=O)c1cn(C2CC2)c2c(F)c(F)c(F)cc2c1=O +Cn1cc(Br)c(=O)c(NC(=O)c2n[nH]c3c2CCC3)c1 +CCC(C)NC(=O)CCS(=O)(=O)c1ccc(Cl)cc1 +Cc1cc(-c2nn3c(C)nnc3s2)ccc1NC(=O)C(C)C +Cn1nnnc1-c1cccc(NC(=O)c2ccoc2)c1 +CC1CN(C(=O)C2CCCN(C(=O)C3CC3)C2)c2ccccc2S1 +O=C(CCNS(=O)(=O)c1cccnc1)Nc1ccc(F)cc1 +Cc1ccc(N2CCC(NC(=O)c3ccn(C)c(=O)c3)C2=O)cc1 +COc1cccc(OC)c1-c1cc(CO)c(C2CC2)o1 +Cc1nnc(NC(=O)N2CCc3nc[nH]c3C2c2ccccn2)s1 +CC(C)CS(=O)(=O)NCC1CCN(S(=O)(=O)C2CC2)CC1 +Cc1ccc(F)c(NC(=O)C(C)Cn2cc(Br)cn2)c1 +CC(C)COc1ncc(CNC(=O)Cn2ccccc2=O)cc1Cl +O=C(CN1C(=O)COc2ccccc21)NC1CCCCC1 +NS(=O)(=O)CCNC(=O)Cc1ccc(-n2cccn2)cc1 +CC1CCC(NC(=O)COCC(F)(F)F)CC1 +CC1CC(C)CN(C(=O)COCc2nc(-c3cccnc3)no2)C1 +COc1ccc(Cl)c(NC(=O)NCc2cccc3cccnc23)c1 +Cc1cc(Br)ccc1NCC(=O)N1CCCCC1 +CCC(=O)c1ccc(S(=O)(=O)N2CC(C)OC(C)C2)cc1 +O=C(Nc1cccnc1)N(Cc1ccco1)Cc1ccco1 +Cc1nnc(CNc2cccc(C#Cc3ccccc3)c2)n1C +CC(=O)N(C)Cc1cccc(NCc2ccc(S(C)=O)cc2)c1 +Cc1cccc(C(O)c2cc(Cl)cc3c2NC(=O)C3C)c1 +CCC(C)CN(C)S(=O)(=O)Cc1ccccc1C#N +CCCCC(NC(N)=O)C(=O)N1CCCC1Cn1cccn1 +CCc1ccccc1NC(=O)C12CCC(C1)C(C)(C)C2=O +Cc1c(C(=O)NCC(=O)OC(C)(C)C)cnn1-c1ccccc1 +CCOc1ccc(Nc2ncnc3c2cnn3CCC#N)cc1 +O=C(CNc1ccc(Cl)cc1)NC1CCCC1 +CN(Cc1ccncc1)S(=O)(=O)c1cccs1 +COc1cccc(NC(=O)NCc2nc(-c3ccc(F)cc3)n[nH]2)c1 +CCCC(=O)NCC(=O)Nc1cccc(NC(C)=O)c1C +Cc1sc(=O)n(CC(=O)NC(C)Cc2ccccc2F)c1C +O=C(NC1CCCc2ccccc21)c1cnns1 +CCOc1ccc(-c2cnc(SC)nc2N)cc1 +Cc1cc(NC(=O)C2CC(=O)N(CC3CC3)C2)[nH]n1 +Cc1ccsc1C(=O)NCc1ccc(OCC(F)(F)F)nc1 +Cc1noc(C)c1C(C)NC(=O)c1cc(C)n(C2CC2)c1C +CCOc1cc2nnc(C(N)=O)c(N)c2cc1Br +CC(C)N(CCO)C(=O)CCSc1ccccc1F +CC(OCc1ccccc1)C(=O)C(C#N)c1nc2ccccc2[nH]1 +Cc1cc2c(SCC(=O)NCC(C)C)ncnc2s1 +C=CCNC(=O)c1cc(OC)cc(Br)c1OC +CC(C)(C#N)C(=O)Nc1cc(Cl)ccc1Cl +Cc1ccc(NC(=O)CCCc2nc3ccccc3s2)nc1 +Cc1ccc(NC(=O)NCCCn2cccn2)c(F)c1 +COC(=O)NCC(=O)NCC(=O)Nc1ccc(Br)cc1 +Cc1n[nH]c2ncc(C(=O)N3CCN(CCC(C)(C)C)CC3)cc12 +Cc1sc(NC(=O)C2CC2)c(C(=O)N2CCc3ccccc32)c1C +COC(CNc1cc(C(N)=O)ccn1)c1ccccc1 +COC(C)(C)c1noc(-c2cc(C)n(C(C)C)c2C)n1 +COCC(O)CNc1nc(-c2ccccc2)nc2ccccc12 +COCCNC(=O)Nc1ccc(Cl)cc1Cl +COCCNC(=O)NC1CCN(S(C)(=O)=O)CC1 +Cc1cc(OCC(=O)N(Cc2ccco2)CC(F)(F)F)nnc1C +Cc1cccc(NC(=O)c2ccc(S(=O)(=O)N3CCCCC3)o2)c1 +CC12OC3(C)C4C(=O)OC1C1(C)OC4(C)C3C(=O)OC21 +COc1cccc(Cl)c1CC(=O)NC(C)c1c(C)noc1C +c1csc(C2CCCN(c3nccc4occc34)C2)n1 +COC(=O)c1ccoc1Cn1cc(-c2ccccc2)nc1SC +Clc1cc(CN2CCc3ccccc3C2)cc2c1OCCO2 +O=C(NCc1ccc2c(c1)OCO2)Nc1cc(F)ccc1F +CCc1cc(N2CCCC(c3noc(CC)n3)C2)ncn1 +Cc1nn(CC(=O)c2ccc(F)cc2)c(=O)c(C#N)c1C +Cc1cccc(C(=O)Nc2ccc(Cl)cc2N)c1 +O=C(Nc1ccc2c(c1)OCO2)N1CCC2(CC1)OCCCO2 +CNC(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +C=CCNC(=O)Cn1nc(C(F)(F)F)n(C)c1=O +Cc1ccc(C(C)(C)C(=O)NCCc2ncc(C)s2)cc1 +Cc1ccncc1NC(=O)NC(C)(C)CNC(=O)OC(C)(C)C +CC(C)COc1ccc(C(=O)NC(C)c2ccncc2)cc1 +CCc1noc(CC)c1CNC(=O)C1CC2C=CC1C2 +COC1C2CCC1N(C(=O)Cc1ccc3c(c1)OCO3)CCO2 +CCOC(C)c1noc(CSc2nnc(-c3ccccc3)o2)n1 +CN(CC1CCCN1C(=O)OC(C)(C)C)c1ncc(Cl)cn1 +Cc1cc(NC(=O)N2CCN(C(=O)C(C)(C)C)CC2)ccc1F +Cc1c(F)cc(C(N)=O)cc1NC(=O)CSc1ccc(F)cc1 +CCNC(=O)N1CCN(CC(=O)Nc2cc(C)on2)CC1 +CCc1nncn1CCNC(=O)N1CCN(CC(F)(F)F)C(C)C1 +Cc1csc(CNC(=O)Cc2csc(C(C)C)n2)n1 +Cc1cnccc1-n1nc(C2CC2)nc1-c1ccccc1-c1nc[nH]n1 +CC1CN(C(=O)c2ccccc2S(C)(=O)=O)CCO1 +COc1ccc(OC)c(CN(C)C(=O)c2cc3ccccc3[nH]2)c1 +CC(C)N1C(=O)c2ccccc2C1C(=O)NC1CCCCC1 +O=C(CCCNC(=O)C1CC1c1ccco1)Nc1cn[nH]c1 +Cc1nn(-c2ccc(F)cc2F)c(C)c1CC(=O)N1CCNC(=O)C1 +CC(C)COCCNS(=O)(=O)c1ccc2c(c1)CCCC2 +N#CC1(c2ccc(C(F)(F)F)cc2)CCOCC1 +COc1ncccc1CNC(=O)c1ccc(=O)n(C)c1 +Cc1ccc(CCC(=O)NC2(C#N)CCOCC2)c(C)c1 +Nc1ccc(C=Cc2ccnc3ccccc23)c(N)c1 +O=S(=O)(NCc1ccccn1)c1ccc(F)c(Cl)c1 +OC(CC1CCCCCN1c1ccc2nccnc2n1)c1ccco1 +CCOc1ccc(C(=O)Nc2cccn3nc(C(C)C)nc23)cc1 +N#Cc1c(-c2ccc(Cl)cc2)c2c([nH]c1=O)CCC2 +CC(C)N(CC(N)=O)c1ccc(Br)cn1 +CCOC(=O)CNCc1c[nH]c2ccc(OC)cc12 +O=c1[nH]cccc1C1NCCc2cccc(C(F)(F)F)c21 +COC(=O)c1ccc(N)c(Oc2cccc(N(C)C)c2)c1 +CCOCCn1cc(Br)c(OC)cc1=O +C#CCN1CCN(C(=O)NCc2cc(C(C)C)no2)CC1 +Cc1ccc(N2CCCC(NCc3ccc(C#N)cc3F)C2)nn1 +CCc1nnc(NCC(OC)c2cccs2)o1 +COc1cccc(OC(C)C(=O)Nc2ccc(C(C)=O)cc2)c1 +Cc1cc(NC(=O)CSc2nnc(-c3ccc(O)cc3)n2C)no1 +Cc1cccc(C)c1OCCCNC(=O)Nc1ccccn1 +O=C(Nc1cccc(-n2cccn2)c1)N1CC2C3CCC(O3)C2C1 +CC(NC(=O)Cn1c(C2CC2)nc2ccccc21)C1CCCO1 +COc1ccc(S(N)(=O)=O)cc1C(=O)Nn1cnc2ccccc21 +CSc1nc(C)c(CCC(=O)Nc2nc(C)cs2)c(C)n1 +Cc1ccccc1Cn1cnc2sc(C)c(C)c2c1=O +COc1ccc(CN(C)c2nn3c(=O)cc(C)nc3s2)cc1OC +COc1cc2c(cc1OC)Cc1cc(OC)c(OC)cc1C2 +COCCCOc1cc2nc(C)sc2cc1N +Cc1cc(S(=O)(=O)NCCOc2ccc(F)cc2)ccc1F +COCC(NC(=O)c1cccc(OC(F)(F)F)c1)C(N)=O +Nc1ccccc1S(=O)(=O)Oc1ccccc1Cl +COc1ccc(C(C)C)cc1-c1cnc(C)nc1N +CCS(=O)(=O)NCCSc1ccc(C(F)(F)F)cn1 +CC(C)CCCC(C)NC(=O)Nc1ccccc1S(C)(=O)=O +COCC1CCCC12CN(CC1CCOCC1)CCO2 +O=C(Cn1ccc(C(F)(F)F)n1)Nc1cnc2ccccc2c1 +Cc1ccc(NC(=O)CCC(=O)Nc2ccc(C)cc2)cc1 +CC(C)(C)OC(=O)N1CCCC(C(O)c2nccs2)C1 +CN1C(=O)CCOc2ccc(-c3cc(N)[nH]n3)cc21 +COCCNC(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1 +NC(=O)N1CCCC(C(=O)Oc2ccc(C(F)(F)F)cc2)C1 +COc1ccc(C(=O)N(C)CCOc2ccc(F)cc2)cc1 +COCC1CC2(CCN(C(=O)c3cnccn3)CC2)CO1 +CCOc1ccc(N2CCCN=C2NC(=O)c2ccccc2)cc1 +O=C(Nc1ccncc1)c1csc2nc(-c3ccc(F)cc3)cn12 +CCNC(=O)CN(CC)C(=O)c1cnc(SC)n1-c1ccccc1 +CC(C)Nc1ncnc(Nc2ccc(F)cc2F)c1N +CC(CNC(=O)NC(C)(C)C)c1nc(-c2ccccc2)no1 +COc1cccc(CN(CC(C)C)C(=O)c2nn(C)cc2Cl)c1 +CCOc1ccc(NC(=O)c2ccc(-n3cccn3)cc2)cc1 +O=C1c2ccccc2CC1Sc1nnnn1-c1ccc(O)cc1 +CC1CCC(NC(=O)CC2COc3ccccc3NC2=O)CC1 +Cc1cc(F)ccc1S(=O)(=O)Nc1cccc(Cn2cccn2)c1 +COc1ccccc1-c1nc(N)nc(C)c1C(N)=O +Cn1cnnc1SCCCc1nc(-c2cccs2)no1 +CCOCCNC(=O)Nc1ccccc1C(=O)N(C)C1CCCCC1 +Cc1noc(NC(=O)c2csc(CC(C)C)n2)n1 +Cc1ccc(SCC2CSc3nc(C)cc(=O)n32)cc1 +Cc1cc(N2CCC(c3nc(C)cc(C)n3)C2)ncn1 +Cc1cnn(C2CN(c3ccnc(-c4ccccc4)n3)C2)c1 +COc1ccc(C=C2OC(=O)c3c2cc(C)[nH]c3=O)cc1 +c1ccc(-n2cc(-c3nc(C4CCOC4)no3)nn2)cc1 +CC1COCCN1C(=O)NCCCSc1ccc(F)cc1 +CC(O)CC1COCCN1C(=O)NC(C)c1ccc(F)cc1Cl +CC(C)CCNC(=O)C1(NC(=O)NCc2ccccc2)CCCC1 +Cc1ccc(N(C)C(=O)c2sc(C)nc2C)c(C)c1 +O=C(COc1ccc(F)cc1F)NCc1ccco1 +CCOC(=O)c1cnn(-c2cccc(C(F)(F)F)c2)c1C +O=C1OC(CC(=O)N2CCN(c3ncccn3)CC2)c2ccccc21 +CN(Cc1cn2ccsc2n1)c1ccc(F)c(F)c1 +O=S(=O)(NCc1cccnc1)c1ccc(-c2ccno2)s1 +CCNC(=O)CCC(C#N)c1ccc2c(c1)OCO2 +COc1ccc(N(C(C)C(=O)NCC(C)C)S(C)(=O)=O)cc1 +COc1ccc(NC(=O)c2cccc3c2NCCC3)cc1 +COc1cc(C(=O)NCc2cccs2)ccc1OC(C)C +CC(CC#N)N(C)Cc1coc(-c2ccc(S(C)(=O)=O)cc2)n1 +CC(C)(C)OC(=O)N1CCCC(S(=O)(=O)c2ccccn2)C1 +COC(=O)c1cc2ccccc2cc1NC(=O)c1ccnnc1 +COc1ccccc1OCc1nc(C#N)c(NCc2ccco2)o1 +Cc1nc(CC(=O)N2CCCc3cc(Cl)ccc32)cs1 +CCCn1nccc1C(=O)Nc1ccn(Cc2ccccc2F)n1 +COc1ccc(-c2noc(CN(C)C(=O)c3ccoc3C)n2)cc1 +CCc1nc(CCNC(=O)C2CCCCC2)sc1C +CC(C)C1CCC(NCc2cccs2)(C(N)=O)CC1 +Cc1nc2ccc(C(=O)NC3CCc4nnc(C)n4C3)cc2nc1C +O=C(CNC(=O)NCC1CCCC1)Nc1ccc(N2CCCC2)cn1 +CC1CCN(C(=O)CCC(=O)c2ccc(F)c(N)c2)CC1 +CC(C)N(C)S(=O)(=O)c1cccc(C(=O)OC2CCCC2)c1 +CCCn1nnc2cc(C(=O)NCc3ccccc3OCC)ccc21 +Cn1ncc(C(=O)Oc2ccccc2)c1-n1cccc1 +CCOC(=O)C1(NC(=O)CNC(=O)C2CC2)CCCC1 +Cc1n[nH]cc1NC(=O)CCc1c(C)nn(C)c1C +COc1ccc2c(c1)CCN2C(=O)NCCC(=O)N(C)C +CCc1nc2n(n1)CCCC2NC(=O)Cn1cc(C)c2ccccc21 +COc1cccc(N2CCC(CNC(=O)NCc3ccccc3)C2)c1 +CCCCCNC(=O)c1nc2ncc(Br)cn2n1 +CCCCN(C)C(=O)CNC(=O)Nc1cccc(C)c1 +CCC(=O)N1CCCCC1C(=O)NCCc1ccc(F)cc1C +Cn1cc(C2CC2C(=O)NCc2ncc(-c3ccccc3)o2)cn1 +O=C(CCC(O)c1cccs1)NCCc1ccccc1 +COc1ccc(C(=O)NCc2cccc(NC(=O)C3CC3)c2)cc1F +Cc1cc(CNC(=O)NCCCN2CCOCC2)cc(C)c1F +Cc1cccc(C2NCCc3ccc(F)c(C)c32)n1 +CCN(CC)c1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccc(F)cc1 +O=C1COc2cc(O)ccc2N1Cc1cccc2ccccc12 +CCC(C)C(=O)Nc1nnc(-c2ccccc2F)s1 +Cc1nn(-c2cccc(Cl)c2Cl)c2c1CNCC2 +O=C(CCC(=O)c1cccs1)Nc1ccccn1 +COc1ccccc1CCNC(=O)C1CCN(C(=O)NC2CC2)CC1 +Cc1cccc(NC(=O)c2nccc3c(N)cc(F)cc23)c1 +Cc1ccc(C)c(CCSc2nncc(=O)n2N)c1 +Cn1nccc1CCC(=O)N1CCC(Oc2cccc(Cl)c2)CC1 +O=C(Nc1nnc(C2CC2)s1)C12CC3CC(CC(Cl)(C3)C1)C2 +Cc1ccc(CNC(=O)N2CCC(N(C)S(C)(=O)=O)CC2)s1 +Cc1c(-c2ccnc(N3CCCC3)n2)cnc2nc(C(F)(F)F)nn12 +COc1ccc(Cl)cc1CC(=O)N1CCN(CCO)CC1 +CC(C)Oc1ccccc1NC(=O)C(C)OCC1CCCO1 +CS(=O)(=O)c1ccc(NC(=O)c2cn3ccccc3n2)cc1 +O=C(NC1CCc2c(F)cccc21)c1cc(Cl)c[nH]1 +Cc1ccnc(NC(=O)c2ccc(COc3ccccc3C#N)o2)c1 +CC(C)(C)C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +Cc1ccc(C)c(C(=O)COc2ccc(S(C)(=O)=O)cc2)c1 +CCN(CC)c1ccc(-c2nnc(SCC(N)=O)n2C)cc1 +CC1Cc2ccccc2N1C(=O)CCS(=O)(=O)N1CCNCC1 +CCc1noc(CC)c1CNC(=O)Cc1cccc(C(F)(F)F)c1 +CS(=O)(=O)c1ccccc1C(=O)NCc1ccncc1 +Cc1cc(CN(C)C(=O)C(C)(C)c2ccccc2)no1 +Cc1ncc(CNC(=O)c2ccc(-n3ccnc3)nc2)s1 +CCc1onc(C)c1NC(=O)c1cccc2ccccc12 +CCCCN(C)S(=O)(=O)c1cccc(C(=O)N(C)C)c1 +Cc1ccccc1CS(=O)(=O)NCC1(C(N)=O)CCOCC1 +O=C(NCC1(c2cccs2)CCOCC1)c1ccco1 +COc1ccc2c(c1OC)CCNC2c1cnoc1C +COc1ccc(C2(Cc3ccccc3C#N)OCCO2)cc1OC +CC(Nc1cccc2c1OCCO2)C(=O)NCc1ccc(F)cc1 +CC(=O)N1CCCN(C(=O)c2cc(N)c(C)s2)CC1 +CN(CCc1ccccn1)C(=O)Nc1nnc(C(F)(F)F)s1 +CN(CCC#N)CC(=O)N1CCCC(C(N)=O)C1 +CC(C)(C)OC(=O)NCC(=O)Nc1ccc(Cl)c(F)c1 +COc1cc(Cl)c(CNC(=O)COc2ccc(C)cc2)cc1OC +Cn1cnnc1-c1ccc(NC(=O)C2CC2c2ccc(F)cc2)cc1 +Cc1noc(CCC(=O)NCCSc2ccccc2)n1 +Cc1ccc2ncc(C(=O)Nc3ccc4c(c3)oc(=O)n4C)n2c1 +O=S(=O)(Cc1ccc(Br)cc1)N1CCOCC1 +CCc1cc(C(=O)NCc2cc(OC)c(OC)c(OC)c2)sc1C +Cc1cc(C(=O)NCC(=O)Nc2ccc3c(c2)OCO3)nn1C +O=C(NCc1ccco1)c1ccc(N2CCCS2(=O)=O)cc1 +O=C(NCCc1nccn1Cc1ccccc1)NCc1ccccc1 +CCOC(=O)c1c(CC)nn(CC(O)c2ccc(Cl)cc2)c1N +Fc1ccccc1-c1nc2ccc(-n3cnnc3)cc2o1 +CCN(CC(C)C#N)C(=O)CNC(=O)c1cccc(C)c1 +Cc1c(C(=O)NCC(C)C#N)cnn1-c1ccc(Br)cc1 +COc1ccccc1C(=O)OCCCc1cccc(C)n1 +OCc1nnn(Cc2ccccc2Cl)c1-c1cccc(F)c1 +COc1cccc(C(=O)NCc2ccc(-n3cncn3)cc2)c1O +COC(=O)c1sc(C(N)Cc2cnc[nH]2)nc1C +NS(=O)(=O)c1ccc(C(=O)OCC(=O)C2CCCCC2)cc1 +O=C(NCCc1ccccc1)C(O)c1ccc(Cl)cc1 +Cc1cc(N)nc(SC(C)c2nc(C)no2)n1 +CCCc1ccc(S(=O)(=O)NC2CCC(O)CC2)cc1 +COC(=O)CC(c1ccc(OC)c(Cl)c1)C(C)C +CC(=O)c1ccc(NS(=O)(=O)c2ccccc2F)cc1 +COc1cc(C(=O)NC2CCC(O)CC2)cc(Cl)c1OC(C)C +CNC(=O)CN(C)C(=O)c1cc(-c2cccc(Cl)c2)on1 +CNS(=O)(=O)c1ccc(CNC(=O)N2CCCC(C)CC2)cc1 +OCC12C=COC1OC2(c1ccccc1)c1ccccc1 +COC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +COCCNC(=O)c1nc(-c2cn(C)cn2)n2ccccc12 +CC1CCN(c2ncc(S(=O)(=O)c3ccccc3)c(N)n2)CC1 +COc1ccc(Br)cc1C(O)CCCC(N)=O +CC(C)NS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C#N)c1 +Nc1cc(F)cc2c(=O)cc(C(=O)Nc3ccccn3)oc12 +CCOCc1ccc(CNC(=O)Cc2ccc(C)nc2)cc1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2ccc(S(C)=O)cc2)c1 +CC(=O)N1CCC(NC(=O)Cn2cccc(C(F)(F)F)c2=O)CC1 +Cc1ccc(C(=O)NCCCN2CCCCCC2=O)cc1 +CCN(Cc1ccccc1)C(=O)CNC(=O)c1scnc1C1CC1 +O=C(CCN1CCn2c(nnc2-c2ccccc2)C1)N1CCOCC1 +CSc1ncc(C(=O)Nc2nc3ccc(C)cc3s2)cn1 +CCn1ccc(C(=O)Nc2ccc3sccc3c2)n1 +CCOCC1CN(C(=O)c2cscn2)Cc2cn(C)nc21 +Cc1ccccc1Nc1nc(N)nc(COc2ccc(C#N)cc2)n1 +CN(C(=O)c1ccc(C(N)=O)nc1)c1ccc(F)cc1 +Cn1cc(C(=O)Nc2ncn(Cc3c(F)cccc3Cl)n2)cn1 +Cc1cc(NC(=O)Cc2cccs2)n(-c2ccccc2F)n1 +COc1cc(C(=O)Nc2ccccn2)cc(OC)c1Br +CC(C)CC(C#N)NC(=O)c1cccc(Br)c1 +COc1cc(C)c(C(=O)NCCCc2cn[nH]c2C)cc1OC +CC(=O)N1CCN(S(=O)(=O)c2cc(C)ccc2O)CC1 +CCc1cc(C(C)Nc2nccc(-c3ccc(C)nc3C)n2)on1 +O=C(Nc1ccccn1)C1(c2cccs2)CCOCC1 +COCCOc1ccc(NC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +Cc1ccc(C)c(S(=O)(=O)N(CCCO)C2CC2)c1 +C=C(C)COc1cccc(C(=O)N2CCN(CCC#N)CC2)c1 +Cc1ccccc1CN1C(=O)COc2ccc(N)cc21 +COc1ccc(-c2cc(=O)c(C#N)c[nH]2)cc1OC +Cn1cc(CCNS(=O)(=O)c2ccc(N3CCCC3=O)cc2)cn1 +CCC(C)NC(=O)CCNC(=O)Nc1cccc(F)c1F +CC(NC(=O)NCc1ccncc1)c1ccc(NC(=O)C2CC2)cc1 +CC1(C)C(=O)N(CC(=O)NCC2CCCO2)c2ccccc21 +COc1cc(CNC(=O)CC(C)(C)C)cc(OC)c1O +CN1CCN(C(=O)CCc2cc(Cl)cs2)CC1 +CC(NC(=O)C1CCC(NC(=O)C2CCCC2)CC1)c1cccnc1 +CNC(=O)c1ccc(CNC(=O)c2ccc3ccn(C)c3c2)o1 +COc1cccc(-c2nnc(SCCC(=O)N(C)C)o2)c1 +O=C(Cn1nc2ccccn2c1=O)Oc1cccc(Br)c1 +O=C(CC1C(=O)Nc2ccccc21)Nc1ccccc1Br +CCNC(=O)c1ccc(NC(=O)N2CCCC2)cc1 +CS(=O)(=O)N1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 +CC(=O)c1csc(NC(=O)c2cc(=O)c3ccccc3o2)n1 +Cc1noc(C)c1CN(C)C(=O)Cn1c(C)nc2ccccc21 +Cc1ccc(C)c(C(=O)C(C)CN2CCOCC2)c1 +CCSc1ccc(C(=O)Nc2cc(OC)ccc2F)cn1 +CC1CC1C(=O)OCc1cc2c(cc1Br)OCCO2 +CC(C)(C)c1nnc(CNc2ccc(F)cc2OC(F)F)o1 +CN(C)C(C(=O)N1CC(c2ccccn2)C1)c1cccc(F)c1 +COc1nc2c(cc1C(=O)N(CCO)Cc1nccs1)CCC2 +COC(=O)N1CCc2ccc(F)cc2C1C(=O)Nc1ncc(C)s1 +Nc1ccc(-c2csc3nnc(C4CCCCC4)n23)cc1 +CCNS(=O)(=O)c1cc(C(C)(C)C)ccc1C +CC(C)NC(=O)CCn1nc(-c2ccc(Cl)cc2)ccc1=O +COc1ccc(C)cc1NC(=O)C(Cc1ccccc1)n1cnnn1 +Cc1ccc2c(CC(=O)NCc3ccc4c(c3)OCO4)coc2c1 +CNc1snc(C)c1C(=O)NCCCCn1c(C)cccc1=O +O=C(Nc1nc2ccccc2s1)c1cccc2cn[nH]c12 +CCCCN(C)S(=O)(=O)Nc1cccc(-c2nnnn2C)c1 +CC(Cn1cc(Cl)cn1)C(=O)NCc1cccc(C(F)(F)F)c1 +Cc1cc(C)nc(NC(=O)NCCc2nc(C)c(C)s2)c1 +CC(=O)N(CCc1ccccc1)CC(=O)NCC1(C)CCC1 +Cc1oc(C)c(C(=O)NCC(=O)N2CCCC2)c1C +Cc1noc(C)c1CC(C)C(=O)N(C)c1cccc2ncccc12 +CC(C)CNS(=O)(=O)c1cccc(C(=O)C(C)C)c1 +Cc1nc(-c2cccc(C(=O)NC3(C)Cc4ccccc4C3)c2)no1 +Cc1nc2c(NC(=O)Cc3c(C)noc3C)cccn2n1 +NS(=O)(=O)CCSc1nnc2n1CCCCC2 +Cc1[nH]ncc1S(=O)(=O)Nc1cc(N)ccc1F +O=C(Cn1nc(-c2ccco2)oc1=O)NCC1(c2ccccc2)CC1 +COCCOc1ccc(NC(=O)c2cccc3cccnc23)cc1F +COc1ccc2[nH]cc(Cc3nc(-c4ccnc(OC)c4)no3)c2c1 +C=CCCC(=O)N1CCC(C(N)=O)c2ccccc21 +CN(CCc1ccc(F)cc1)C(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +Cc1cc(C(=O)NCCCN2CCCC2=O)sc1-c1ccccc1 +Cc1ccccc1OCCCC(=O)Nn1cnc2ccccc2c1=O +COC(=O)c1sc2nc(CSc3ncccn3)[nH]c(=O)c2c1C +Cn1cccc1C(=O)N1CCN(C(C(N)=O)c2ccccc2)CC1 +CC(C)NC(=O)CCn1c(=O)[nH]c2ccsc2c1=O +CC(NC(=O)c1cccc(CCC(C)(C)O)c1)c1nncn1C +CCN1CC(C(=O)OCc2noc(-c3ccc(F)cc3)n2)CC1=O +Cn1c(CNc2ccc3c(c2)C(=O)CCC3)nnc1-c1ccccc1 +COc1ccc(NC(=O)N(Cc2cccc(O)c2)C2CC2)cn1 +O=c1[nH]c(CN2CCOC(c3ccc(F)cc3)C2)nc2ccccc12 +COc1ccc(F)c(NC(=O)c2ccc(NC(=O)C(C)C)cc2)c1 +CCCOc1ccc(CNC(=O)Nc2ccc3c(c2)COC3)cn1 +Cc1ccc(CNC(=O)Cn2cnc3sc(C)cc3c2=O)cc1 +CCn1nc(C#N)cc1-c1ccc2c(c1)ncn2C +CCc1ccc(NC(=O)c2ccc(F)cc2)cc1N +COc1cc(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)ccc1F +N#Cc1ccc(NCC(=O)NCc2nncn2-c2ccccc2)cc1 +O=C(CCc1cscn1)OCc1cccs1 +NC(=O)N1CCCC(C(=O)NC2(c3ccc(Cl)cc3)CCCC2)C1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)NCc1ccc(F)cc1 +CCCN(C)C(=O)Nc1cccc(-n2cnnn2)c1 +COCCNC(=O)N1CCN(C(=O)c2ccc(Cl)cc2F)CC1 +CCCc1cc(C(=O)N2CCN(C(=O)C3CCCCC3)CC2)no1 +Cc1cc(NC(=O)Nc2ccccc2)n(-c2ccccc2)n1 +CCC(=O)N1CCCN(C(=O)c2cnn(C(C)CC)c2C2CC2)CC1 +Cc1ccc(C)c(-c2cc3c4n[nH]c(=O)n4ccn3n2)c1 +CCCC(=O)NCC(=O)Nc1ccc(Oc2ncccn2)cc1C +O=S1(=O)N=C(CN2CCOC3CCCCC32)Nc2ccccc21 +Cc1cc(C)n2nc(C)c(C(=O)N3c4ccccc4CC3C(N)=O)c2n1 +O=C1CCCCC1Sc1nccn1-c1ccc(Cl)cc1 +O=C(CCc1cccc2[nH]ccc12)Nc1ccc2c(c1)OCO2 +O=C(Nc1ccc(NC(=O)C2CCCO2)cc1)C1CCCCC1 +CCc1ccc(CCC(=O)Nn2cnc3ccccc3c2=O)cc1 +CC(=O)NCc1nc2c(cnn2-c2ccccc2)c(=O)[nH]1 +COc1ccc(CCC(=O)Nc2ccc(C)c(N)c2)cc1 +COc1ccccc1Cc1nc2ccc(C)cn2n1 +CC(=O)N1CCN(C(=O)c2cc3c([nH]c2=O)CC(C)(C)CC3=O)CC1 +O=C(NCc1ccnc(OC2CCC2)c1)Nn1cnc2ccccc21 +COc1ccc(NC(=O)NCC(O)c2ccsc2)cc1OC +C=CCC1(CO)CCCN(S(=O)(=O)c2cn(C)nc2C)C1 +COc1ccc(CC(=O)NCC2(c3ccccc3)CCOCC2)cc1 +Cc1cccc(C(=O)Nc2nc(-c3cccnc3)cs2)c1 +CCOCCNC(=O)N1CCCC1c1cc(OC)ccc1OC +O=C1CC(C(=O)N2CCc3ccccc32)CN1c1ccc(Cl)cc1 +CCCn1nccc1NC(=O)CNC(=O)c1cc(C)oc1C +CC(O)c1nc2ccccc2n1Cc1ccc(Cl)cc1 +CC(C)(CNC(=O)COC1CCCCC1)C(N)=O +CCOC(=O)CN(C)S(=O)(=O)c1ccccc1Cl +COCC1CCCN(C(=O)CCS(=O)(=O)c2ccccc2)C1 +CCOc1ccc(-c2nc(CN(C)S(C)(=O)=O)c(C)o2)cc1 +CCOC(=O)c1ccccc1OS(=O)(=O)N(C)C +C=CCN(CC=C)C(=O)C1(C)Sc2ccccc2NC1=O +COC(=O)c1ccc(Nc2ncnc(N3CCC(C)CC3)c2N)cc1 +Cc1cc(C)c(CNC(=O)c2cnn(-c3ccccc3)n2)c(=O)[nH]1 +CC1COCC(C)N1C(=O)c1scnc1C1CC1 +Cc1nccn1Cc1cccc(CNC(=O)C2CC3C=CC2C3)c1 +CC(C)CCN(CCC(C)C)C(=O)c1cnc2sccn2c1=O +COc1cc(-n2ncc(OC)c(Cl)c2=O)nc(-c2ccccc2)n1 +Cc1ccccc1C(=O)OCC(=O)c1cc(C)n(C)c1C +COc1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1 +COc1cccc(CCC(=O)NC2CC(=O)N(CC(F)(F)F)C2)c1 +Cc1cccc(C(=O)N2CCc3ccc(CNC(=O)C4CC4)cc32)c1 +Cn1cc(CNc2cccc(-c3nccs3)c2)nn1 +CC(=O)N1CCc2cc(C(=O)N(C(C)C)C3CCCC3)ccc21 +NC(=O)CNC(=O)c1csc(Nc2cccc(C(F)(F)F)c2)n1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)NCc1ccc(C#N)cc1F +Cc1ccc(-n2ccnc(NCc3ccccc3Cl)c2=O)cc1 +Cc1ccc(C(=O)NCC#CCOc2cccnc2)cc1C +CCN(CC(=O)N(C)Cc1cccc(C#N)c1)c1ccccc1 +CC(C)c1nc2sc(C3CCCO3)nn2c1C#N +Cc1ccc(C(C)NC(=O)COC2CCCCC2)o1 +O=C(N1CCc2ccccc2C1)N1CCCCCC1c1ccncc1 +CCc1c(C(=O)Nc2ccccc2OC)cnn1-c1ccccc1 +Cc1cccc(C(=O)Nc2ccc(OCc3nccn3C)cc2)c1O +Cc1ccccc1COC1CCN(C(=O)c2ccc(F)cc2C)CC1 +COC(=O)c1sc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)nc1C +Cc1nc(COc2cccc(C(=O)NCC(N)=O)c2)oc1C +CCc1cccc(CC)c1NC(=O)NCCCOC +CCc1nnc2n1CC(Nc1ccc3nnnn3n1)CC2 +Cn1cc(C2(C)CN(C(=O)c3cccc4cc[nH]c34)CCO2)cn1 +O=C(CCC1CCCC1)N1CCC2(CC1)OCCCO2 +CCOCC(=O)Nc1ccc(Br)c(C(F)(F)F)c1 +COc1cccc(CNC(=O)c2ccc(-n3ccnn3)cc2)c1 +CCc1onc(C)c1NC(=O)Cn1c(=O)[nH]c2ccccc2c1=O +CCn1cc(-c2nnc(SCc3ccc(F)cc3)n2CC)cn1 +COc1ccc(CNc2ccc3oc(C)nc3c2)c(OC)c1 +N#CC(C(=O)C1COc2ccccc21)c1nc2cc(F)ccc2s1 +Cn1c(CNC(=O)Cn2nc3ccccn3c2=O)nc2ccccc21 +O=C(c1cscn1)N1CCCCC1Cn1cccn1 +O=C(CCCC1CCCCC1)N1CCC(CO)CC1 +CN1C(=O)CC2(CCN(C(=O)CCO)CC2)c2ccccc21 +CCOc1ccccc1NC(=O)COC(=O)c1ccc(F)cc1 +Cc1[nH]ncc1S(=O)(=O)N1CCCCC1CCO +CCn1c(=O)n(CC)c2cc(-n3ccnc3-c3ccncc3)c(C)cc21 +COc1ccc(OC)c(CN(C(=O)Nc2nc(C)cs2)C2CC2)c1 +COc1ccc(OC)c(-n2c(C)c3c(C)nnc(C)c3c2C)c1 +Cc1ccccc1CNC(=O)CCc1ccccc1N +CC(C)CC1COCCN1C(=O)c1ccc(C#N)cc1 +COc1ccccc1CNC(=O)CNC(=O)c1cccc(Cl)c1 +CCCCOc1cccc(-c2cnn(CC)c(=O)c2C#N)c1 +CC1(NC(=O)Cn2c(=O)oc3ccccc32)CCC1 +COc1ccc(NC(=O)c2cc(S(N)(=O)=O)ccc2OC)cc1 +CN(C)c1ccc(NC(=O)c2cnn(Cc3ccccc3)c2)cn1 +CCc1n[nH]c(CC)c1NC(=O)c1cccc(Cl)c1 +Cn1cc(OCc2ccccc2Cl)c(=O)cc1C(=O)NC1CC1 +O=c1cccnn1CCNS(=O)(=O)c1cc(F)ccc1F +Cc1cc(O)c2cc(C(=O)Nc3ccccn3)ccc2n1 +CCc1ncc(NC(=O)CCCc2cc(F)ccc2F)cn1 +COC(C)(C)CNC(=O)C(c1cccc(F)c1)N(C)C +CCn1nc(C)c2nc(C(C)C)nc(N3CCOCC3)c21 +CCCN(CCC)C(=O)Cn1c(CO)nc2ccccc21 +Cc1occc1-c1nc(NC2CC2)ncc1-c1cnccn1 +Cc1ccccc1CS(=O)(=O)N1CCN(c2ccccc2)CC1 +CCC1(CNC(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)CCC1 +O=C(CCc1ccc(F)cc1)Nc1ccn(CCc2ccncc2)n1 +CSc1ccc(C(=O)N2CCN(C(=O)CC3CCCC3)CC2)o1 +CCOC(=O)c1cc2c(cnn2-c2ccccc2)c(C)n1 +CC(Sc1n[nH]c(N)n1)C(=O)N1CCOCC1 +Cc1cc(C(=O)Nc2cccc(-n3cnnn3)c2)c2c(C)nn(C)c2n1 +O=S(=O)(NCC1CCCCC1)c1cccs1 +Cc1nc2ccccc2n1CCCNC(=O)COC1CCCCC1 +COCCCNC(=O)c1ccc(-c2ccc(F)cc2)nc1N +O=C(Nc1ccc(Cl)c(F)c1)c1ccc(N2CCC(O)CC2)cc1 +C=CCCCN(C)C(=O)c1sc(CC(C)C)nc1C +CCn1ccc(C(=O)Nc2sc3c(c2C(=O)OC)CCCC3)n1 +Cc1ccc(-c2nnc3[nH]c(=O)n(C)c(=O)c3n2)cc1 +COc1cccc(-c2cc(CC(=O)NC(C)(C)C)no2)c1 +CC(NS(=O)(=O)c1ccccc1)C(=O)Nc1cccnc1 +Cc1cc2ncc(C(=O)N3CCCC3c3ccccc3)c(C)n2n1 +COc1ccc(-c2nc3cc(C)ccc3[nH]2)cc1N +CN1CCC2(CCN(C(=O)OC(C)(C)C)CC2)C1=O +COc1nccc(N(C)Cc2noc(C(C)C)n2)c1C#N +CCOC(=O)C1CCCN(C(=O)c2cnc3n(c2=O)CCS3)C1 +COC1CCN(C(=O)c2cn(Cc3ccccc3)nn2)CC1 +Cc1ccc(NC(=O)N2CCN(CCC(=O)N(C)C)CC2)cc1 +CC1COCCN1CC(=O)N(C)C(C)c1ccc(Cl)cc1 +CC(=O)N1CC(NC(=O)C2COc3ccc(F)cc3C2)C1 +CC(C)(CC1CCOCC1)C(=O)N1CCCCC1 +Cc1csc(N2CCCN(C(=O)C3CC=CC3)CC2)n1 +Cc1cc(C(=O)Nc2cnn(Cc3ccc(F)cc3)c2)no1 +O=C(Nc1ccccc1)C1CCCN1C(=O)Cc1noc2ccccc12 +Cc1noc(C)c1Cc1nnc2sc(-c3cccc(F)c3)nn12 +CN(CCC(F)(F)F)C(=O)Cc1ccc2c(c1)OCO2 +COc1ccc(CNc2ccc(Cl)cn2)c(F)c1 +Cc1cc(Br)cnc1NCC(=O)NCC(C)C +COc1cccc(C(=O)N(C)c2ccc(Cl)cn2)c1F +CCCCc1nnc(NC(=O)CN2CCOCC2CC)s1 +COC(=O)CNc1ccccc1C(=O)NCC(F)(F)F +Cc1nc(NC(=O)COC(=O)c2cccs2)c(Cl)cc1Cl +O=C(NCc1cccc(O)c1)c1cc(F)cc(Br)c1 +CC(OC(=O)c1ccc(C#N)cc1)c1ccc2c(c1)OCCO2 +CCN1C(=O)CCCc2cc(C(O)C3CCCO3)ccc21 +Cc1nn(C(C)C)c2cnn(CCNC(=O)c3cccnc3)c12 +COc1ccc(Cl)cc1CS(=O)(=O)c1nnc(C2CC2)n1C +Cc1nc(CC(=O)NCCOc2ccc(C(F)(F)F)cn2)cs1 +O=C(Nc1cccs1)N(Cc1ccsc1)C1CC1 +Cc1cccc(C)c1OCC(CC#N)N1CCCC1 +COCC(C)(O)CNS(=O)(=O)c1ccccc1Br +COC(=O)C1CCN(c2ncnc(N3CCC(C)CC3)c2N)CC1 +CNC(=O)CNC(=O)c1sccc1-c1ccc(F)cc1 +CC1CCCCN1S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +CCCc1nnc(NCc2c(C)nn(CC)c2C)o1 +CC(C)(C)c1ncc2c(n1)CN(C(=O)c1ccccc1Cl)C2 +Cc1cccc(-c2nnc(NC(=O)c3cc(C)n(C)n3)o2)c1 +CCn1cc(NC(C)c2ncc(-c3ccccc3)o2)cn1 +CNc1ncc(Br)cc1S(=O)(=O)NC(C)(C)C +CCCn1cc(NC(=O)Nc2ccc(Oc3cccnc3)nc2)cn1 +COC(=O)c1c(C)[nH]c(C(=O)OCc2nccn2C(F)F)c1C +CCCCNC(=O)c1ccc(OCC2CCCO2)cc1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3ccco3)CC2)cc1C +COc1ccccc1CCCNc1ccc(S(N)(=O)=O)cc1 +c1coc(-c2cc(CSc3nnc4ccccn34)no2)c1 +COCC(NC(=O)c1cccc(Oc2ccccc2)c1)C(N)=O +O=C(NC1CC1c1cccc(Cl)c1)c1cccc(-n2ccnc2)c1 +O=C(NCc1ccc(F)cc1)N1CCN(CC(O)C2CC2)CC1 +O=C(CN1CCCC1=O)NCCC1CN(C2CCCCC2)CCO1 +COC(=O)Nc1ccc(OC(=O)Cc2ccc(F)cc2)cc1 +Cc1nn(-c2ncccn2)c2c1C(C(=O)c1ccccc1)CC(O)=N2 +O=C(Cn1c(-c2ncccn2)noc1=O)N1CCc2sccc2C1 +CCC(=O)Nc1nc(-c2c[nH]c(C(=O)OC)c2)cs1 +CC(C)COCCC(=O)Nc1ccc(F)c(C(N)=O)c1 +Cc1nn(-c2ccc(F)cc2F)c(C)c1C(=O)N=c1sccn1C +CC(C)OC(=O)c1ccc(CSc2nncc(=O)n2N)o1 +Cc1nc(-c2c(-c3ccccc3)ncn2CCNc2ccccc2)c[nH]1 +COC(=O)C(C)Sc1nnc(-c2ccccc2)o1 +CS(=O)(=O)c1ccccc1NC(=O)COc1ccccc1Cl +O=S1(=O)N=C(NC2CC2)Nc2ccc(F)cc21 +O=C(OC1CCCc2ccccc21)c1ccc(-n2cncn2)cc1 +O=C(NCc1cn(-c2ccccc2)nn1)c1ncoc1C1CCCO1 +CC(CCN1CCOCC1)NC(=O)C1(c2cccc(F)c2)CCCC1 +O=C(Nc1nc2c(s1)CCCC2)c1ccc(=O)oc1 +COc1ccc2c(c1)CN(C(=O)CNC(=O)C1CCCC1)CC2 +CNc1cnn(-c2ccc(OC)c(Cl)c2)c(=O)c1 +COc1c(C)cc(CN(C)C(=O)C(C)NC(=O)c2ccoc2)cc1C +CCOC(=O)C1CN(C(=O)OC(C)(C)C)CCC1(F)F +CC(OCC(F)(F)F)C(=O)NCc1cn2ccccc2n1 +CCOC(=O)CN(C(=O)C1CC(=O)N(C(C)C)C1)C(C)C +CC(CO)NC(=O)NCc1cccc(NC(=O)C2CCCC2)c1 +O=C(N1CCCCC1)N1CCN(CC(O)Cn2cccn2)CC1 +CC(NC(=O)c1cccc(N)n1)c1cccc(Br)c1 +Cc1cc(C)c(C(=O)N2CCOC(c3nccs3)C2)c(C)c1 +CCCCC(=O)Nc1ccccc1C(=O)N(CC)CC +Cn1c(Nc2cccc(CO)c2)c(C#N)c(=O)n(C)c1=O +Nc1cc(N)nc(SCC(=O)N2CCCC2c2cccs2)n1 +O=c1cc(COn2nnc3ccc(Cl)cc32)nc2sccn12 +O=C(NCCS(=O)(=O)c1ccccc1)c1cccc2ccccc12 +C#CCN1CCN(CC(=O)N(C(C)C)C2CCCC2)CC1 +Cc1cc2ncnc(N(C)CC(=O)NC(C)C)c2cc1C +O=C(NCCCO)Nc1ccc(NC(=O)NCc2ccco2)cc1 +COc1c(C)cnc(CNC(=O)NCc2ccc(C(N)=O)cc2)c1C +CCC(=O)Nc1ccc(C)c(NC(=O)c2cc(C(N)=O)cs2)c1 +O=C(Nc1nc(C(F)(F)F)cs1)c1cccnc1 +O=c1oc2cccnc2n1Cc1ccc(S(=O)(=O)C(F)F)cc1 +Fc1cc(Cl)c2c(c1)CCNC2C1CCOCC1 +Cc1cc(N2CCC(c3nccnc3N(C)C)CC2)ncn1 +COC(=O)Nc1cccc(NCc2ccsc2)c1 +Cc1csc(C(C#N)C(=O)c2cccc(OC3CCCC3)c2)n1 +COCc1nc(Cn2ccnc2-c2[nH]cnc2C)no1 +CC(=O)N(CCc1ccccc1)CC(=O)N(C)c1ccc(F)c(F)c1 +CCOc1ccccc1S(=O)(=O)NCC1(O)CCc2ccccc21 +CCn1cc(C(=O)N2CCCC2c2ccc(OC)cc2)cn1 +COc1ccc(NC(=O)CNc2ccc(C#N)cc2)cc1 +CCC(CO)Nc1nccc2c(N)ccc(Cl)c12 +CCC(C)NC(=O)C(C)Nc1ccc(N2CCCS2(=O)=O)cc1 +Cc1cc(C)c2c(n1)oc1c(=O)n(CCc3ccccc3)cnc12 +Cc1c(C)c2ccc(NC(=O)COc3ccccc3F)cc2[nH]c1=O +CC(C)(C)c1cnc(CN2CCc3c(N)cccc3C2)o1 +Cc1noc(C)c1CN(C)C(=O)c1cc(C(C)C)n2ncnc2n1 +Cn1nccc1CNC(=O)c1cc2cc(Br)ccc2[nH]1 +CCN(Cc1cn2cc(Cl)ccc2n1)CC(C)C#N +COC(=O)c1ccc(C(=O)Nc2ccc(F)cc2OCC2CC2)cn1 +CCOC(=O)c1cn(C2CC2)c2c(F)c(F)c(OC)cc2c1=O +COc1c(Cl)cccc1NC(=O)N1CCOC(C)(C)C1 +CC1CCCC(NS(=O)(=O)c2cnn(C)c2)C1 +Cc1noc(CCNC(=O)COc2ccc(C(C)C)cc2)n1 +COc1ccccc1OC(=O)Cc1nc2nc(C)cc(C)n2n1 +N#Cc1nn(-c2cccc(C(F)(F)F)c2)c(=O)[nH]c1=O +O=C(NCc1ccccc1)c1cccc(NCc2cscn2)c1 +COC(=O)c1occc1CNC(C)Cc1ccco1 +CC1CCCC(NC(=O)c2ccc(S(C)(=O)=O)cc2)C1C +CCN(C(=O)CNc1cc(F)c(F)cc1F)C1CC1 +CN(CCOc1ccccc1F)C(=O)COc1ccccn1 +Cc1csc(NC(=O)CCCC(=O)N2CCNC(=O)C2)n1 +CC(C)(C)OC(=O)N1CC(O)C(O)C(O)C1CO +Nc1nc(COC(=O)CCc2ccsc2)nc2ccccc12 +CCCNC(=O)C1CCCN(Cc2sc(N(C)C)nc2C)C1 +CN(CC(=O)N1CCOCC1(C)C)c1cnccn1 +C=CCn1cccc(C(=O)Nc2ccc(OC)c(OC)c2)c1=O +Cc1noc(C)c1CC(=O)Nc1cccc(Cl)c1C +Cc1nc2ncnn2c(C)c1CCC(=O)OCCc1cccs1 +CCC(c1ccncc1)N(CC)C(=O)c1cccc(-c2ccoc2)c1 +C=CCN(CC=C)C(=O)c1ccc(Br)cc1 +Cc1c(NC(=O)C23CC4CC(C)(CC(C)(C4)C2)C3)cnn1C +COC(=O)c1cc(-c2csc(NC(=O)C3CC=CCC3)n2)c[nH]1 +c1ccc2[nH]c(N3CCCN(CC4CCCCO4)CC3)nc2c1 +Cc1ccc(-c2nnn(CC(=O)N(C)C3CCCCC3)n2)cc1 +COC(=O)CC(NC(=O)CC1CCCO1)c1cccs1 +COc1ccc(C(=O)Nc2ccccc2C#N)cc1Br +O=C(OCc1ccc(-n2cccn2)cc1)c1ccco1 +Cc1csc(C2CN(Cc3nc(C)c(C)o3)CCO2)n1 +O=C(CCNC(=O)c1nc2ccccn2n1)NCc1ccco1 +C#CCN1CCC(C(=O)Nc2ccc3[nH]c(C)cc3c2)CC1 +O=C(NCCN1CCOCC1)Nc1ccccc1N1CCCC1=O +CC(C(=O)NCCc1ccccc1)N1C(=O)CCCc2ccccc21 +CCC(=O)Nc1ccc(O)c(C(=O)N(CCO)Cc2ccccc2)c1 +N#Cc1cccc(C(=O)Nc2ccc3c(c2)CN(C(=O)C2CC2)CC3)c1 +O=C(CSc1ccncc1)N1Cc2cncnc2C1 +COc1ccc(-c2n[nH]c(C)c2-c2ccc3c(c2)OCCO3)c(O)c1 +C=C(c1ccccc1)C1NCCc2ccc(O)cc21 +Cc1ccc(S(=O)(=O)NCCCNC(=O)c2cccs2)cc1 +O=C(NCc1ccccn1)N(Cc1cccc(F)c1)CC1CCCO1 +CCCCCNC(=O)c1cc(=O)c2cc(N)cc(CC)c2o1 +Cc1cc(CN(C)C(=O)Nc2ccccc2N2CCCC2)no1 +CCn1nc(C)c(S(=O)(=O)NCCCn2cccn2)c1C +Cc1ccc(C(=O)Oc2cccc(S(C)(=O)=O)c2)s1 +CCN(CC)c1ccc(C(=O)N2CCCCC2Cn2cccn2)cn1 +COc1ccccc1NC(=O)c1cc2c(=O)n3ccccc3nc2n1C +CCN(CC)C(=O)c1cccc(NC(=O)c2cccc3[nH]ccc23)c1 +CCc1cc(N(C)CC2(CO)CCC2)n2nc(C)c(C)c2n1 +N#CCCn1cc(C(=O)COc2ccccc2F)c2ccccc21 +CCc1nnc(NC(=O)NCc2cc(Br)cs2)s1 +Cc1ccc2nc(C)n(C3CCN(C(=O)C(C)C)CC3)c2c1 +CCCS(=O)(=O)N1CCCC1C(=O)NC1CCCC(C)C1C +O=C(Nc1ccccc1)N1CCC(Oc2ccccc2)CC1 +NC(=O)CCCNC(=O)c1cc(N2CCCC2=O)ccc1Cl +CC(=O)c1ccc(COC(=O)c2cc3ccccc3oc2=O)cc1 +O=C(NCC1CC1)Nc1c[nH]c2c(Cl)cccc2c1=O +CCc1nnc2n1CC(NC(=O)c1ccc(-c3cnco3)cc1)CC2 +O=C(NCCN1CCc2ccccc21)C1CCCCO1 +COCCNC(=O)CSc1cnnc2ccc(C)cc12 +CCSc1cc(C(=O)NCc2ccco2)ccn1 +Cc1ccc2c(COc3ncnc4sccc34)cc(=O)oc2c1 +COC(=O)Cc1csc(NC(=O)Cn2cncn2)n1 +COc1ccccc1OCCCC(=O)Nc1ccc2c(c1)OCCO2 +CCn1c(=O)[nH]c2cc(-c3nc(-c4ccccc4)no3)ccc2c1=O +O=C(Nc1ccc(F)cc1)C1CCN(C(=O)Nc2cccs2)CC1 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1nc2ccccc2s1 +COc1ccc(Nc2nc(N)nc(N)c2C#N)cc1 +O=C1OC(C(=O)NCCc2ccc(F)cc2)Cc2ccccc21 +CSc1cccc(C(=O)Nc2nnc(-c3cc(C)oc3C)o2)c1 +CC(Sc1nc(N)cc(N)n1)C(=O)NCCC1=CCCCC1 +CCCOc1c(Br)cc(C2NC(=O)CN2C)cc1OC +COc1ncccc1CNC(=O)NCC1CCCO1 +Cc1nc2ccccc2c(=O)n1CCOC(=O)c1cc2ccccc2o1 +Cc1nc(NC(=O)CCn2c(=O)cc(C)c3ccccc32)sc1C +O=C(Nc1nccs1)c1cc(Sc2ncccn2)ccn1 +COc1ccccc1-n1nc(CC(C)C)nc1C1CCC(O)CC1 +Cc1ccc(CNC(=O)NC(C)C2CCCO2)c(OCC2CC2)c1 +CCn1cc(C=c2sc3nc(O)c(N)c(=O)n3c2=O)cn1 +CC1CCCC(CNC(=O)c2cccc(OCC(=O)N(C)C)c2)C1 +CCCC(C(=O)OCc1ccccn1)c1ccccc1 +O=C(Cc1ccc(Cl)cc1)N1CCn2nncc2C1 +COC(=O)C(C)(C)N(C(=O)Cc1csc(C)n1)C(C)C +COc1ccc(Cl)cc1-c1cc(NC(C)=O)[nH]n1 +CCC(C)(C)NC(=O)CNc1cc(C(=O)N2CCOCC2)ccc1C +Cc1ccc(CCNCc2ccc(C#N)cc2)cc1 +Cc1onc(-c2ccccc2)c1C(=O)NCCc1cccs1 +CC(=O)N(c1ccc2c(c1)OCO2)c1c(C)nc2ccccn12 +CCC(CC)N(C)C(=O)c1cccc2c1OCCO2 +CC(C)(C)CC(=O)NCC(=O)N1CCc2cc(F)ccc2C1 +COc1ccc(OC)c(CN(C)C(=O)c2cc(C(N)=O)cs2)c1 +COc1ccccc1CNc1nc(C)nc2sc(C)cc12 +Cc1cccc(C)c1NC(=O)CNC(=O)c1ccccc1F +NC(=O)c1n[nH]c2ccc(NC(=O)CCc3ccc(F)cc3F)cc12 +Cc1ccc(S(=O)(=O)CC(=O)Nc2cccc(F)c2)cc1C +Cc1nccnc1SCC1CCCN(C(=O)OC(C)(C)C)C1 +CC(NC(=O)c1cccc(Br)c1)c1nnc2n1CCC2 +O=C(Cc1csc(NC(=O)c2cnccn2)n1)NC1CCCC1 +Nc1c(N2CCCCCC2)ncnc1N1CCCC1 +Cc1cc(C)n(CCNC(=O)c2cc(-c3cccn3C)n[nH]2)c(=O)n1 +Oc1cc2c(cc1OC(F)F)C(c1ccoc1)NCC2 +CCOC(=O)c1csc(NC(=O)CCc2ccccc2F)n1 +Cn1c(SCc2coc(-c3cccs3)n2)nnc1C1CC1 +CCN(CC)C(=O)c1ccccc1NC(=O)COc1ccc(C)cc1 +Cc1nnc(C2CCCN(S(=O)(=O)c3ccccc3)C2)s1 +COCc1nc2ncc3c(n2n1)CC(c1ccc(C)cc1)CC3=O +CSc1cccc(NC(=O)C2CCCN(S(C)(=O)=O)C2)c1 +O=C(Nn1cnc2ccccc2c1=O)c1ccc(Cl)cc1 +FC(F)(F)CCc1ccnc(NCc2cnc3c(c2)CCC3)n1 +Cc1cccc(NC(=O)CCn2cnc3ccccc32)n1 +Cc1cc2nnc(Sc3ccncn3)n2c2ccccc12 +OC(Cn1cnc2ccccc21)c1ccc(OC(F)F)cc1 +COc1cccc(-c2nc(N)nc3ccccc23)c1 +CC(C(N)=O)N1CCN(C(=O)c2ccc(Cl)cc2F)CC1 +COc1cccc(C(=O)N(CCC#N)Cc2cccnc2)c1OC +CC(NC(=O)CCc1cccnc1)C1CCCCC1 +O=C(Nc1ccc(Br)cc1F)c1ccoc1 +Cc1cc(C(=O)NCc2ccc(Cl)cc2)ccc1N +CCCC1CN(C(=O)Nc2ccc(OC)nc2C)CCO1 +CCOc1ncccc1CNC(=O)Cc1cccc2ccccc12 +CCOC(=O)CCCNC(=O)Nc1ccc(Br)cc1C +Cc1noc(C)c1CN(C)C(=O)c1ccc(F)cc1 +CC(c1cccs1)n1ccnc1-c1cccc(O)c1 +Cc1cc(C)nc(N2CCCC(C)(c3[nH]ncc3C)C2)n1 +Cc1nc(CNC(=O)NC(c2ccccc2F)C2CCCC2)no1 +Cc1ccc(S(=O)(=O)NC(C)(C)CSc2ncn[nH]2)cc1 +Cc1nc(C(=O)NCC(=O)NCc2ccco2)c(-c2ccccc2)o1 +O=C(CCNC1=NS(=O)(=O)c2ccccc21)NCC1CCC1 +CC(C)n1nccc1NC(=O)c1cccc(F)c1F +Cc1cc(C(=O)COc2ccc(F)cc2F)c(C)[nH]1 +Cc1cc(C)c(C(=O)N2CCCC(c3cc(=O)[nH]c(C)n3)C2)c(=O)[nH]1 +CCOc1cc(F)ccc1NC(=O)c1cccn1C +COc1cc(NC(=O)c2ccc(Cl)cc2)c2ncccc2c1 +COc1ccc(C)cc1-n1nnnc1SCCCC#N +CCC(CC)C(=O)Nc1nnc(-c2cc(C)oc2C)o1 +O=C(NCc1cccnc1)c1cnn(Cc2ccccc2)c1 +COc1cccc(CCNc2ncnc3[nH]ncc23)c1OC +Cc1nc(CNC(=O)N2CCC(O)(C(F)(F)F)CC2)c(C)s1 +C=CCOC(=O)C(C)NC(=O)c1cccc(Cl)c1Cl +CCn1nc(C)cc1C(=O)N(C(C)C)C1CCOCC1 +CCN(CCO)c1ncc(Br)cc1C +Cc1cc(C(F)(F)F)nc(CCN2CC3(CCOC3)CCC2=O)n1 +CCc1cc(-n2cnnc2)cc(C)c1NC(=O)C(C)(C)C +O=C(Cc1nc(CO)cs1)Nc1cccc2ccccc12 +CCC(=O)N(CC1CCCO1)c1nc2ccc(F)cc2s1 +COc1ccc2nc(CC(=O)c3ccoc3C)[nH]c(=O)c2c1 +CNC(=O)CCCC(=O)c1ccc(CC(C)C)cc1 +CCc1ccc(C(=O)N(C)C(C(N)=O)c2cccc(F)c2)o1 +CC=CCCNC(=O)c1sc(C)c(Br)c1OC +CCCC(C(=O)Nc1cccc(N)c1)n1cc(Cl)ccc1=O +CN(C)C(C(=O)NCCCc1ccc(O)cc1)c1cccc(F)c1 +O=S(=O)(NCCc1cccs1)c1ccccc1Br +Cc1cccnc1CNC(=O)NCC(C)Oc1ccccc1F +CCOC(=O)c1cc(S(=O)(=O)NC(C)(C)CC)c(C)n1C +O=C(c1csc(-c2ccc(N3CCOCC3)nc2)n1)N1CCCC1 +CCC(C)(C)NC(=O)C(C)N1CCN(C(=O)c2cnccn2)CC1 +CC(C)c1nn(C)cc1CN(C)C(=O)NCC(C)(C)c1ccncc1 +CCC1(CC)CN(CC(O)CO)c2ccc(O)cc2O1 +CCC(CC#N)NC(=O)c1cc(C)c(F)cc1F +COCC(C)NC(=O)c1ccccc1Br +O=C(NCc1ccc(F)cc1)Nc1cnn(CCO)c1 +CC1CC(=O)N(CC(=O)Nc2ccc(Cl)cc2N)C1 +COc1ccc(C(=O)Nc2c[nH]cc(Br)c2=O)c(F)c1 +OCc1nnn(-c2ccccc2F)c1-c1cccc(F)c1 +NC(=O)C1CCN(c2nc3ncc4c(c3c(=O)[nH]2)CCC4=O)CC1 +CN(CCOc1ccc(Cl)cc1)C(=O)c1ccc(C(N)=O)cc1 +Cc1cc(N2CCC(=O)C2)ccc1Br +Cn1cc(-c2ncnc3c2CCN(C(=O)c2ccoc2)CC3)cn1 +CC(C)COc1cccc(C(=O)Nc2ccccc2C(=O)N(C)C)c1 +COc1cccc(-n2nnc(C(=O)NCC(C)C)c2C)c1 +Cc1ccc(C(=O)Nc2cc3c4c(c2)CCN4C(=O)CC3)cc1C +CCOC1CCCN(C(=O)c2ccc(Br)cc2O)C1 +COc1nn(C)cc1C(=O)NCC#CCOc1ccccc1C +C#CCOC(=O)c1ccccc1C(=O)N(CC)CC +Cc1cccc(C)c1-n1nnnc1SCC(=O)NC(C)(C)C +Nc1nc(CSc2ccc(F)cc2)nc2ccccc12 +O=C(Nc1ccc(NC(=O)C2CC2)nc1)NC1CC1 +N#CCCn1c(-c2ccc(N)cc2)nc2cccnc21 +Cn1nc(-c2cccc(NS(C)(=O)=O)c2)ccc1=O +COc1ccc(NC(C)=O)c(NC(=O)c2cccc3cccnc23)c1 +COCCn1nc(C(=O)N2CC(O)C2)ccc1=O +CC(C)(C)n1ncc(C(=O)N2CCNC(=O)CC2)c1C(F)(F)F +CCN(C)c1ccc(C(=O)NCc2ccc3ccccc3n2)cc1 +CCN(CCc1nc2ccc(C)cc2[nH]1)C(=O)c1ccccc1C#N +CCc1nc2n(n1)CCCC2NC(=O)NCC1CC1c1ccccc1 +CC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2cc(C)sc2C)c1C +Cc1ccc(C(C)OC(=O)c2cc(C(N)=O)cs2)cc1 +CCOC(=O)c1cccnc1-c1ccc(S(C)(=O)=O)cc1 +Cc1n[nH]c(C)c1NC(=O)c1cccc2ccccc12 +CCc1cc(=O)[nH]c(SCC(=O)N2CCCCC2)n1 +CC(=O)NCCNC(=O)N(C)C(C)Cc1ccc(Cl)cc1 +CC(=O)c1ccc(Br)cc1OCC(C)(C)O +CC(=O)Nc1ccc(OCCCOc2ccc(F)cc2F)cc1 +COC(=O)NCCC(=O)NC1CCCc2ccccc21 +COc1ccc(C(=O)NCCc2ccc(F)cc2)c(N)c1 +CN(C(=O)Cc1ccc(Cl)cc1)C(C#N)c1ccccn1 +COCC(NC(=O)Cc1ccc2c(c1)CCCC2)C(=O)OC +N#Cc1cccnc1N1CCN(C(=O)C2(c3ccccc3)CC2)CC1 +CC(C)c1cccc(NC(=O)NCCCc2n[nH]c(=O)[nH]2)c1 +O=C(Cn1ncc2ccccc2c1=O)Nc1ccc(F)c(F)c1 +O=S(=O)(c1ccccc1)c1ccc(OCCn2cccn2)cc1 +COc1ccc(Cl)cc1CNC(=O)NCC(=O)N1CCCC1 +Cc1cccc(=NS(=O)(=O)c2cccs2)[nH]1 +CCOC(=O)C1=C(N)OC(C)=C(C(=O)OC)C1c1cccnc1 +Cc1cnc(C(=O)Nc2ccc3c(c2)CC(=O)N3)cn1 +CC(=O)NCC1CCN(C(=O)c2scnc2C)CC1 +CC(C)CC(=O)N1CCCC1C(=O)c1ccc(F)cc1 +N#CCn1cnc2c(cnn2-c2cccc(Cl)c2)c1=O +Cc1csc(CNc2ccccc2C(=O)N2CCOCC2)n1 +Cc1nc(CCNC(=O)c2cc(F)ccc2Br)cs1 +Cc1cc(C)c(C(=O)Nc2ccc(Oc3cccnc3)nc2)o1 +CNC(=O)c1cccc(OC(=O)CSc2cc(C)ccc2C)c1 +CC(C)(C)NC(=O)c1cc(Br)ccc1F +CCc1noc(CC)c1CC(=O)Nc1cc(-n2cccc2)ccc1F +CC(=O)NCCNCC(=O)c1ccc(Br)cc1 +COC(=O)Cc1ccc(-n2ncc3cc(N)ccc32)cc1 +CCOC(=O)CCNC(=O)c1cc(F)cc(Br)c1 +C=CCNC(=O)Cc1nc(COc2ccc(Cl)cc2)n[nH]1 +CCOc1ccc(-n2c3c(cc(C#N)c2=O)CNCC3)cc1 +Cc1cc(NC(=O)Cn2cnc3ccccc3c2=O)[nH]n1 +CCC(CO)NS(=O)(=O)N1CC(C)OC(C)C1 +CC(C)COCCCNC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +Cc1ccn2cc(C(=O)NCc3ccc4c(c3)OCCO4)nc2c1 +CCc1ccc(Cn2ncnc2-c2cc(C#N)cn2C)cc1 +Cc1ccc(C(=O)c2ccccc2C(=O)NCCO)cc1 +COCCn1cnc2ccc(NC(=O)c3c(C)noc3C)cc2c1=O +Cc1cc(NC(=O)NCCCO)ccc1Oc1cccnc1 +CCOC(=O)C1(NC(=O)c2ccc(OCC)nc2)CCCC1 +O=C(N1CCN(Cc2cccnc2)CC1)C12CC3CC(CC(C3)C1)C2 +N#Cc1cn(C2CC2)c(=O)n(CC(=O)c2ccc3c(c2)CCO3)c1=O +O=C(COC1CCCCC1)Nc1ccc(Oc2cccnc2)nc1 +CN1CCN(C(=O)c2c(-n3cnnn3)sc3c2CCC3)CC1 +CNC(=O)CCC(C#N)c1cccc(Br)c1 +O=C(CSc1nncn1C1CC1)Nc1ccc(OC(F)F)cc1 +Cc1cccn2c(=O)c(C(=O)NCCc3ccco3)cnc12 +CCC(C(=O)NCc1cc(-c2ccccn2)n(C)n1)c1ccccc1 +O=C(NCC1OCCc2ccccc21)c1cccc2ccnn12 +Cc1nc(C)c(C(=O)N2CCCc3c(F)ccc(F)c32)o1 +Cc1nnc(C(C)Sc2nc3ccc(Cl)cc3o2)o1 +Cc1sc(NC(=O)c2cccc3ccccc23)c(C(N)=O)c1C +Cc1ccsc1CN1CCc2nc(N3CCOCC3)ncc2C1 +CCOC(=O)c1cc(N2CCOCC2)nc2ccccc12 +CC(=O)Nc1ccc(F)c(C(=O)N2CCCC(NC(C)=O)C2)c1 +COCCNc1nnc(SCC(=O)N2CCC(C)CC2)s1 +C=C(C)COc1cccn2c(-c3cccc(N)c3)nnc12 +Fc1ccc(CCNC2CCSc3ccccc32)cc1 +O=C(NCCCNc1ncccn1)c1cccc(-n2cccn2)n1 +COCCCNC(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CCn1ccc(C(=O)Nc2nnc(-c3cccc(F)c3)o2)n1 +COc1ccc(OC)c(CNCCN2CCOCC2)c1 +CCOC(=O)c1ccc2[nH]c(-c3ccccc3)cc(=O)c2c1 +COCC(O)CN(C)C(=O)COc1cccc(Cl)c1C +CCNS(=O)(=O)CCNC(=O)N(C)CC1CCC1 +CCn1c(C(C)NC(=O)Cc2ccc(C)nc2)nc2ccccc21 +CC(=O)Nc1ccc(SC(C)C(=O)Nc2cccc(C#N)c2)cc1 +COC(=O)c1cccc(C(=O)Nc2cc(C)nn2C)n1 +CC(=O)NC(C(=O)Oc1ccc(NC(=O)C2CC2)cc1)C1CCCC1 +O=C(NCc1cccc(F)c1)N1CCN(Cc2ccncc2)CC1 +CS(=O)(=O)N1CCCC(C(=O)Nc2ccc(F)cc2)C1 +CCOc1c(OC)c(Cl)cc2c1C(CC(C)C)NCC2 +CC(=O)c1ccccc1NC(=O)COC(=O)Cc1ccc(Cl)cc1 +O=C(Nc1cn[nH]c1)Nc1cccc(N2CCCS2(=O)=O)c1 +Cc1nn(C)c(C)c1S(=O)(=O)NC(C)c1oc2ccccc2c1C +O=C(Nc1cccc(NC(=O)c2cnccn2)c1)c1cccnc1 +Cc1cccc(C)c1NC(=O)c1cc(F)cc(F)c1 +Cc1n[nH]c(C)c1NC(=O)c1oc2ccccc2c1C +CN(C)C(=O)C(Cc1ccc(F)cc1)c1ccc(N)cc1 +CCC(=O)N1CCc2cc(Br)cc(N)c21 +Cn1cccc1C(=O)NCC1COc2ccccc2O1 +Cc1cccc2nc(-c3cncc(Br)c3)nn12 +C=CCOC(=O)N1CCNCC1C(=O)OC(C)(C)C +O=C(NCC1CCCCO1)c1cccc2[nH]ccc12 +COc1ccc(SC(C)C(=O)NC(C#N)CC(C)C)cc1 +Cc1ccc(CC(=O)NCCc2nnc3ccccn23)cc1 +CC1CN(CC(=O)NCc2ccco2)c2ccccc2S1 +COCC(C)N(C)S(=O)(=O)c1c(C)cccc1N +COc1cccc(NC(=O)CN(Cc2ccno2)c2ccccc2)c1 +COc1ccc(OC(F)F)c(NC(=O)NCCO)c1 +Cc1ccc(NC(=O)Nc2nc(-c3cccnc3)cs2)cc1 +Cc1oncc1C(=O)Nc1ccc(CC(=O)NC2CC2)cc1 +O=C(CCn1ccccc1=O)N1CCN(Cc2ccccn2)CC1 +Cc1oc(-c2nc(-c3ccccn3)no2)cc1S(N)(=O)=O +CC(C)c1nc(C(=O)NC(C#N)C(C)(C)C)nn1-c1cccc(F)c1 +Cc1nn(C)cc1-c1cc(C(F)F)nc(N2CCCC2)n1 +Cn1cc(-c2nc(CSc3n[nH]c(=O)n3C)cs2)cn1 +NS(=O)(=O)c1cc(C(=O)NCCc2cccs2)cs1 +CCOCCC(=O)N1CCC(c2ccc3ccccc3c2)C(O)C1 +CCCCn1nnnc1Cn1ncc(Cl)c(Cl)c1=O +O=C(c1c[nH]c2ccc(F)cc2c1=O)N(CCO)Cc1nccs1 +C#CCNC(C(=O)Nc1ccc(OC)cc1)c1ccccc1 +COc1cc(OC)cc(-c2ccc(OC)c(O)c2)c1 +Cn1nc(C(=O)N2CC(C)(C)C(O)(C3CC3)C2)ccc1=O +CC(C)CNC(=O)N1CCCC(C(=O)NCC(=O)NC2CC2)C1 +N#CCn1nc(-c2ccccn2)nc1-c1ccccn1 +Cc1cccc(NCC(=O)Nc2ccc(C(N)=O)cc2)c1 +CCNC(=O)c1ccc(NC(=O)Cc2cccc(O)c2)cc1 +CC1CCN(S(=O)(=O)c2cccn(CC(N)=O)c2=O)CC1 +O=C(N1CC(OCc2ccccc2)C1)C1(c2ccc(F)cc2)CC1 +Cc1ccc(-n2nnc(C(=O)NC(C)C)c2C(C)C)cc1 +O=C(Nc1ccc2c(c1)OCCO2)C1CSc2nccc(=O)n2C1 +CCOC(=O)C1CCCN(C(=O)CNC(=O)c2cccc(F)c2)C1 +Cc1cc(NC(=O)CNc2cccc(C(F)(F)F)c2)on1 +Cc1nn(C)c(C)c1C(=O)Nc1ccc(Cl)c(C#N)c1 +Cc1cc(C(=O)Nc2cccc(-c3nnc4n3CCCCC4)c2)[nH]n1 +COc1cc(CNc2c(F)cccc2F)cc(OC)c1OC +CCc1ccc(NC(=O)C(C)Sc2ccc(N)nc2)cc1 +CS(=O)(=O)N1CCN(CC(=O)Nc2cccc3ccccc23)CC1 +O=C(CCC(=O)OCc1ccccc1)Nc1nccs1 +Brc1cncc(NCCOCC2CCCO2)c1 +CCC(=O)Oc1ccc(N(C)S(=O)(=O)c2ccc(F)cc2)cc1 +COCc1ccc(C2CCCN2C(=O)Nc2cc(C)n(C)n2)o1 +CCCCCN1C(=O)C(C(C)C)Oc2cc(N)ccc21 +Nc1cc(F)c(Oc2ccc(F)cc2F)c(F)c1 +CNc1snc(C)c1C(=O)OC(C)C(=O)Nc1ccccc1F +Cc1ccc(S(=O)(=O)NCC2CCOC2)c(Cl)c1 +O=C1COc2ccc(C(=O)CSc3nc4ccccc4o3)cc2N1 +CC1(C)Nc2ccccc2C(=O)N1Cc1ccc(Cl)c(Cl)c1 +C=C(C)CN(CC)C(=O)NC(C)c1cccc(S(N)(=O)=O)c1 +Cn1cccc1C1CCCCN1C(=O)c1cccc(OCC(F)F)n1 +COC(=O)c1nn(C)c(C)c1NC(=O)CNC(=O)C(C)C +CNC(=O)Cn1ccnc1-c1cncc(Br)c1 +COCCNC(=O)N(Cc1ccc(C)s1)C(C)C +Cc1nn(CC(=O)N(C)c2ccc(F)c(F)c2)c(=O)c2ccccc12 +COc1cccc(-c2c(CO)nnn2-c2nnc(C)s2)c1 +Fc1ccc(CCNCc2cnn(-c3ccccc3)c2)c(F)c1 +COCCCC1CCCCN1C(=O)c1c[nH]c(C)cc1=O +Cc1n[nH]c(C)c1N1CCN(C(=O)CCn2ccc(=O)[nH]c2=O)CC1 +CC(C)CC(NC(=O)c1ccc2sncc2c1)C(=O)N1CCCC1 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)c1cccc(C#N)c1 +CCN1CCN(S(=O)(=O)CCNC(=O)c2cccs2)CC1 +C=CCOC(=O)C1=C(C)NC(=O)NC1c1cccc(F)c1 +O=C1CSc2ccc(C(=O)OCCOc3ccccc3F)cc2N1 +COc1ccc(C(=O)N2CCCC(COCc3ccccc3)C2)cc1 +CCCc1nnc(C(=O)N(C)Cc2cccc3cccnc23)o1 +COc1ccc(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)cc1F +Cc1ccccc1OC1CN(C(=O)C2CC(=O)OC23CCCCC3)C1 +CC(=O)Nn1c(C(C)(C)C)nc2ccccc2c1=O +Cc1cc(F)ccc1NC(=O)NC(C)C(=O)N1CCCCC1 +CN(Cc1ccncc1)C(=O)c1ccc(Cl)c(Cl)c1 +Nc1cc(=O)[nH]c(SCC(=O)Nc2ccccn2)n1 +COc1c(F)ccc2c1CCNC2c1cnccn1 +CSc1nc(-c2ccco2)nc(C)c1C(=O)OCc1cc(C)on1 +O=C1Cc2cc(NC(=O)Nc3ccc(Cl)cc3)ccc2N1 +COC(=O)C(C)N(C(=O)c1cc(C)oc1C)C1CC1 +O=S1(=O)C=C(Sc2cccc3cccnc23)c2ccccc21 +CN(C)C(=O)c1cccc(OC(=O)CCn2ccc3ccccc32)c1 +CCN(CC)S(=O)(=O)CC(=O)Nc1cc(OC)ccc1F +CCCn1c(SCC(=O)Nc2nnc(C(C)C)o2)n[nH]c1=O +CC(NC(=O)CC(C)(C)C)c1nnc2ccccn12 +C#CCNS(=O)(=O)c1ccc(C(=O)NCc2nncn2CC)cc1 +COc1ccc(CN2C(=O)C(O)CC2c2cccnc2)cc1 +Cn1cc(CCC(=O)N2CCCC(Nc3ccc(F)cc3)C2)cn1 +NC(=O)C(OC(=O)c1cc(Cl)c[nH]1)c1ccc(F)cc1 +CC(C)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1 +CC(=O)N1Cc2cc(N)ccc2Oc2ccccc21 +COC(=O)c1cc(-c2cc(Cl)cc(C)c2OC)on1 +COC(=O)C(C)(C)NC(=O)c1cc(C(C)(C)C)n[nH]1 +Cn1c(CN2C(=O)c3ccccc3CS2(=O)=O)nnc1C1CC1 +CCOc1ccc(F)c(C(=O)NC(C)Cc2cc(C)[nH]n2)c1F +COC(=O)C1=C(C)Nc2nc(SC)nn2C1c1ccoc1 +CC(C)c1ccccc1NC(=O)CCn1ccnn1 +O=C(CCc1ncc(-c2ccccc2F)o1)NCCCO +COC(=O)c1ccoc1COC(=O)c1n[nH]c2ccccc12 +Cc1c(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cnn1C +N#Cc1ccc(C(=O)Nc2ccc(Cl)c3ncccc23)cc1 +COc1cc(C(=O)NC2CCCCC2C)cc(OC)c1OC +COc1cc(CNC(=O)OC(C)(C)C)cc(C(C)=O)c1 +Cc1cc(=O)[nH]c(SCC(=O)N2CCN(c3ccccc3)CC2)n1 +CCOC(=O)C(CC)n1c(N)nc2cc(Cl)ccc21 +Cc1csc(CS(=O)(=O)c2ccc(C(C)C)cc2)n1 +Cc1n[nH]c(SCCNC(=O)C(c2cccnc2)N2CCCC2)n1 +Cn1cnnc1-c1ccc(NC(=O)N2CCC(F)(F)CC2)cc1 +CN(CCO)C(=O)CC1C(=O)NCCN1Cc1cccc(F)c1F +COc1ccc(NC(=O)CC(NC(C)=O)c2ccc(C)cc2)cn1 +O=C(Cn1cccn1)Nc1cccc(NC(=O)c2cccs2)c1 +CCCN(CCC)C(=O)CC(C#N)c1ccccc1C +CCCc1nc(CSc2nc3c(cc2C#N)CCCC3)no1 +O=C(Cc1cccc(C(F)(F)F)c1)NCCNC(=O)C1CC1 +CCOCC1CCCN(C(=O)c2ccc(-n3cncn3)cc2)C1 +CN1C(=O)C(C)(C)COc2ccc(C(=O)C3CC3)cc21 +Cc1cc(OC(=O)Cn2cnc3c(cnn3C)c2=O)cc(C(C)C)c1 +CCCc1ccc2c(c1)C(C(O)c1ccc(O)cc1)NCC2 +CSc1ccc(CNc2cnn(CC(F)(F)F)c2)cc1 +CC(=O)c1ccc(C(=O)Nc2cccc(N3CCCC3=O)c2)s1 +CC(=O)Nc1cccc(NC(=O)c2ccc3c4c(cccc24)CC3)c1 +COc1ccc(S(=O)(=O)NCCN2CCOCC2)cc1 +O=C(Nc1cccc(-c2cn[nH]c2)c1)c1ccc2ccccc2n1 +Cc1cccc(CN(C(=O)CCn2cnc3ccccc32)C2CC2)c1 +O=C(CNCC(F)(F)F)N1CCc2sccc2C1 +CC1CCCCC1NC(=O)c1ccc2c(c1)NC(=O)C1CCCN21 +CS(=O)(=O)c1cccc(-c2ccc(O)c(Cl)c2)c1 +CC(CC1CCCCC1)C(=O)N1CCOC(C(N)=O)C1 +CC1(CNC(=O)NCC(C)(C)c2ccncc2)CCCO1 +COc1cc2c(cc1-c1nccn1Cc1ccccn1)CCC2 +O=C(CSc1ncn[nH]1)Nc1c(F)cccc1F +CN(CCCc1ccccc1)C(=O)C1CN(c2ncccn2)CCO1 +Cc1cc(=O)c(C(=O)OCC#N)nn1-c1ccc(Cl)cc1 +COC(=O)N1CCCC(C(=O)N2CCc3cc(F)ccc3C2)C1 +Cc1cc(C)c(C#N)c(SCCN2CCOC2=O)n1 +O=C(NCC1(O)CCCc2ccccc21)c1ccc(-n2ccnc2)nc1 +NC(=O)c1cc(-c2ccc(N)cc2)nc2ccccc12 +NS(=O)(=O)c1ccccc1NCCC1CCCO1 +COc1ccccc1N1CCN(C(=O)C(C)CC(N)=O)CC1 +O=C(NCc1cccs1)C1CCN(C(=O)NC2CC2)CC1 +Cc1csc(C2(NC(=O)c3ccc(S(C)=O)cc3)CCCC2)n1 +CC(=O)Nc1cccc(C(=O)NCC2(c3ccccc3)CCC2)n1 +CC(NC(=O)C1CCCCC1)C(=O)N1CCc2cc(F)ccc2C1 +CCCc1cc(CNC(=O)c2cccc3ccnn23)on1 +Cc1ccc(NC(=O)Cn2ccc(C(F)(F)F)n2)c(C)c1 +O=C(NCC1CCCO1)C1CCCN1C(=O)OCC(F)(F)F +COc1ccc(NC(=O)CNc2cccc(C#N)c2)cc1 +Nc1cnc(-c2ccc3c(c2)ncn3C2CC2)nn1 +CC1CCC(N(C)C(=O)c2ccc(Cn3cccn3)cc2)CC1 +CCN(C(=O)C1CC(=O)N(C)C1)C(C)c1cc2ccccc2o1 +COC(=O)CC(C)c1nc(-c2ccc3c(c2)CCC3)cs1 +CC(CN1CCOCC1)NC(=O)c1cccc2cn[nH]c12 +O=C(Nc1nnc(Cc2ccc(F)cc2)s1)C1CCCO1 +N#Cc1c(COC(=O)CC2C(=O)Nc3ccccc32)cn2ccccc12 +COc1ccc(S(=O)(=O)n2ccnc2C)c2ccccc12 +Cn1ncc2c(N3CCN(C(=O)NC4CCCCC4)CC3)ncnc21 +Cc1nc(C)c(C(=O)OCc2nc(-c3ccccc3)no2)s1 +COCc1ccccc1NCc1ccc(OC)c(F)c1 +CC(c1ccccc1)N(C)C(=O)COc1ccc(F)cc1 +Cc1ccc(C(O)c2ccc3c(c2)C(C)C(=O)N3)cc1 +CCOc1ccc(N2CCN(CC(=O)Nc3ccccc3)C2=O)cc1 +O=C(COC(=O)C1(O)CCCC1)N1CCOC2CCCCC21 +CC(C)NC(=O)Cc1ccc(NC(=O)N2CC(C)OC(C)C2)cc1 +O=C(NCCCn1ccc2ccccc21)c1ccnc(F)c1 +Cn1cc(NC(=O)c2cc3ccccc3[nH]2)cc(Br)c1=O +Cc1[nH]ncc1S(=O)(=O)NC(C)c1ccc(Cl)cc1 +CC1(C)C(NC(=O)Cc2csc(-c3ccccn3)n2)C2CCOC21 +COc1ccc(F)c(NC(=O)c2ccc(OC)c(OC)c2)c1 +COC(=O)C(C)CN(C)C(=O)Oc1ccccc1 +CCOCCNC(=O)N1CCN(CC(=O)N2CCCCC2C)CC1 +Cc1csc(CNC(=O)NC2CCc3ccccc32)n1 +Cc1noc(C2CCCN(C(=O)c3cccnc3-n3cccn3)C2)n1 +CC(Oc1ccc(Br)cc1)C(=O)N(C)C(C)C +COc1ccc2[nH]cc(C(=O)Nc3nccs3)c(=O)c2c1 +COc1ccnc(N2CCN(C(=O)CCNC(N)=O)CC2)n1 +CCOc1ncccc1C(=O)Nc1ccc(OC)cc1 +O=C(NCc1cccnc1-n1cncn1)c1cccc2cn[nH]c12 +Cn1c(=O)n(CC(=O)N2CCCC2Cn2cccn2)c2ccccc21 +O=C(CCCNC(=O)c1c(Cl)ccc(Cl)c1Cl)NC1CC1 +CCOC(CC)C(=O)NC1CCc2ccccc2C1 +C=CCNc1nc(-c2ccc3c(c2)CC(C)N3S(C)(=O)=O)cs1 +CCc1nc2n(n1)CCCC2NC(C(N)=O)c1ccc(F)cc1 +COc1ncc(NC(=O)N2CCc3sccc3C2)cc1C(N)=O +CCCNC(=O)c1ccc(N2C(=O)C(C)CS2(=O)=O)cc1 +Cc1cc2nc(-c3ccncc3)n(CCC#N)c2cc1C +COC(=O)c1cc(-c2cc(C(F)(F)F)ccc2OC)n[nH]1 +COc1ccc(OCCc2nc(C(C)C)c(CO)s2)cc1 +N#CCCCOc1cccc(CN2CCOCC23CCC3)c1 +Cc1ncc(-c2ccc(NC(=O)Cc3ccc4c(c3)OCO4)cc2)o1 +COc1ccnc(NC(=O)Cc2ccc(C(F)(F)F)cc2)c1 +Cc1nc(-c2ccccn2)n(Cc2nnnn2-c2ccccc2)n1 +CC(C)(NC(=O)c1ccncc1)c1cccc(Cl)c1 +Cc1n[nH]c(C)c1NC(=O)c1cccc(N(C)C)c1 +O=C(NCc1ccnc2ccccc12)Nc1ccccn1 +O=C(Cn1cccnc1=O)NCc1cccc(N2CCCC2=O)c1 +Cc1c(-c2cc(NCCO)nc3[nH]ccc23)c(=O)n(C)c(=O)n1C +CCC(CC)C(=O)N1CCOc2c(O)cc(-c3cccnc3)cc2C1 +COc1cccnc1C(=O)N1CCc2c(nc[nH]c2=O)C1 +C#CCOc1ccccc1CNc1ccc2[nH]nc(C(N)=O)c2c1 +CCC(C)n1nccc1NC(=O)c1ccc(F)cc1 +Cc1ccc(-n2cc(-c3ccc(C(=O)N4CCOCC4)cn3)cn2)cc1 +COc1ccccc1CC(=O)NC1CCc2nnc(C(C)C)n2C1 +CC(c1nc(C2CC2)no1)N1CCN(c2ccc(C#N)cc2F)CC1 +CC(Cn1cncn1)Nc1cc(-c2ccccc2F)nc2ccnn12 +COCCOc1ncccc1C(=O)NCc1nnc2n1CCCC2 +Cc1ccc(C(CN2CCOCC2)NC(=O)c2ccc[nH]c2=O)cc1 +Cn1cc(NC(=O)C2CC2c2ccco2)cc(Br)c1=O +CCCCn1c(CN2CCOCC2)nc2c1c(=O)[nH]c(=O)n2C +O=C(NCCc1cccnc1)c1cc(-c2cccnc2)on1 +COc1ccccc1-n1nnc(C(=O)Nc2ccccc2)c1C +COc1ccc(CNC(=O)C2CC3C=CC2C3)cc1 +COCCNC(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +CC(C)C1CN(C(=O)c2ccccc2Cl)C(CO)CN1 +COCCCC1CCCN(c2ncnc3c2CCC3)C1 +CC(c1nc(N)nc(N(C)C)n1)N1CCN(CC(F)F)CC1 +CC1CCCN(S(=O)(=O)NCc2cccs2)C1 +CCn1ccc2sc(C)c(C(=O)NCc3ccccc3F)c2c1=O +CCC(c1ccncc1)N(CC)C(=O)NC1CC(=O)N(C(C)(C)C)C1 +CCCOC(=O)c1cccc(NC(=O)COC)c1 +COc1cccn(Cc2nnc(-c3cccnc3)o2)c1=O +CCc1ccc(C(O)CCC(=O)NCC(C)C)cc1 +CC(C)c1ccccc1NC(=O)C(N)c1ccccc1 +O=C(Nc1cnn(Cc2ccccc2)c1)c1cc2c([nH]c1=O)CCCC2 +CC(C)Oc1ccc(CNC(=O)NC(C)C2CCCO2)cc1 +CSc1ncccc1C(=O)N(C)Cc1nc2ccccc2s1 +CCN(CC)C(=O)c1cccc(-n2c(C)nc3cccnc32)c1 +Cc1ccc(OCC(=O)Nc2ccc(N3CCOCC3)nc2)cc1 +O=C(CC1CCCC1)NCc1noc(COc2ccccc2)n1 +CC(C)(C)CC1CCCN1C(=O)Nc1cccnc1-n1cncn1 +Cc1nn(C)c(C)c1C(=O)Nc1nc(C(C)C)cs1 +Cn1nc(C(=O)NCC(=O)C(C)(C)C)cc1NC(=O)C1CC1 +Cc1noc(C)c1CC(=O)OC(C)C(=O)N1c2ccccc2CC1C +Cc1cc(C(F)F)nn1CC(=O)NCc1ncc[nH]1 +CCNC(=O)N(Cc1ccccc1)Cc1ccc(OC)c(OC)c1 +COCc1ccccc1NC(=O)CCn1cccn1 +Cc1cc(CNC(=O)CCn2cnc3sccc3c2=O)ccc1F +O=C(Nc1cc2c(cc1Cl)OCCO2)c1ccsc1 +CCc1csc(C2CCCN(C(=O)c3cnn(C(C)(C)C)c3)C2)n1 +CS(=O)(=O)NCC12COCC1CN(C(=O)c1ccccc1)C2 +c1ccc(-n2cnnn2)c(NCc2ccncn2)c1 +Cc1occc1C(=O)Nc1nnc(C(F)(F)F)s1 +CCOC(=O)c1nc(Cn2c(C(F)(F)F)nc3ccccc32)no1 +CC(C)(C)c1cc(C(=O)NCc2ccco2)ccn1 +CC(O)c1ccc(NS(=O)(=O)N2CCOCC2)cc1 +CCOC1CC(N(C)C(=O)Cc2csc(C)n2)C1(C)C +CN(C)c1ccc(C(F)(F)F)cc1NC(=O)c1csnn1 +CC(=O)Nc1nc(C2CCN(C(=O)c3cnco3)CC2)cs1 +O=C(NCc1ccc(-c2cccnc2)cc1)c1ccnc2ncccc12 +Cc1ccc(C(=O)NCc2cccnc2-n2cccn2)c(=O)[nH]1 +Nc1cnn(CCCc2cccc(Br)c2)c1 +CC(=O)N1CCN(C(=O)C(C)Sc2ccc(C(C)C)cc2)CC1 +Cc1noc(C2CCN(C(=O)CCOc3ccccc3Cl)CC2)n1 +CCC(CC)NC(=O)C(C)NS(=O)(=O)c1ccc(Cl)cc1 +COc1ccccc1S(=O)(=O)NC1CCCCCC1 +Cc1cc(NC(=O)CCc2cc3ccccc3o2)no1 +CCOc1ccc(NC(=O)CCc2nc3ccccc3c(=O)[nH]2)cc1 +CC(=O)NCCNC(=O)c1nc(N2CCCC2)ncc1Cl +Cc1cc(C)n2c(C(=O)N3CCC(O)(CO)CC3)nnc2n1 +CCOc1ccccc1OCc1ccc(S(=O)(=O)N(C)C)o1 +CCOc1ccc(NC(=O)c2cc(N)ccn2)cc1 +COCCC1NCCc2c(OC)ccc(OC)c21 +Nc1ccc2nc(CC(=O)Nc3cccc(F)c3)ccc2c1 +CC(C)CNC(=O)C(NC(=O)c1cc2ccoc2s1)C(C)C +CNC(=O)CN1CCN(C(=O)CC(C)CCc2ccccc2)CC1 +CCC1COC(C)CN1CCn1cc(N)ccc1=O +COc1cccc(CNC(=O)Cn2ccc(C(F)(F)F)n2)c1 +COc1cc(C)c(C(=O)NCc2cc(C(C)C)no2)cc1OC +CCC(NC(=O)NCc1ccn(C(C)C)n1)c1ccncc1 +CCc1cccc2c(C3=CCN(C(=O)c4nccnc4N)CC3)c[nH]c12 +CNc1nnc(SCc2nc3ccsc3c(=O)[nH]2)s1 +CCC(NCC(=O)OC)c1ccc(Cl)c(Cl)c1 +O=C(CCN1CCCC1=O)Nc1nc(-c2ccccc2Cl)cs1 +CC(Sc1nnc(NC2CCCCC2)s1)C(N)=O +CC1CCN(C(=O)Cn2ccc(-c3ccccc3)n2)CC1 +CC(OC(=O)C(C)N1CCc2ccccc2C1)c1nc2ccccc2[nH]1 +COC(=O)CN(C)C(=O)c1sccc1-n1cnnn1 +CC(=O)c1cccc(NC(=O)Nc2ccc3c(c2)oc(=O)n3C)c1 +CN(Cc1nccn1C(F)F)c1ccc(F)c(F)c1 +CCC(C)N(C)C(=O)NCc1ccc(COC)cc1 +O=C(NCCNC(=O)C1CC1)Nc1ccc(F)c(Cl)c1 +Cc1cc(C(=O)Nc2ccc(-n3ncc(C#N)c3N)cc2)ccc1F +OC(COc1ccccc1)CN1CCc2nc3ncccc3cc2C1 +O=C(c1ccc(Cl)cc1F)N1CCC(CO)C1 +Cc1cnn(CC(=O)N2CCN(C(=O)c3ccc(F)cc3F)CC2)c1 +O=C(NCc1ccco1)c1ccc(C(=O)c2ccccc2)cc1 +C=CCCCN(C)C(=O)NCc1csc(CC)n1 +Cc1ccc(C(=O)Nc2ccc(-n3cncn3)c(F)c2)s1 +CCN(CCC#N)CC(=O)c1sccc1Br +CCOCCC(=O)Nc1sc(CC)cc1C#N +CCc1cc(C#N)c(NC(=O)Cc2c(C)noc2C)s1 +C=CCn1nnc(NC(=O)COc2ccc(Cl)cc2)n1 +COc1ccccc1OCCNC(=O)c1cc(C)nc2ccccc12 +COc1ccc(-c2cc3ncn(CC#N)c(=O)c3s2)cc1 +COc1ccc(NC(=O)N2CC(Oc3ccccc3OC)C2)c(C)c1 +COc1ccc(C(C)NC(=O)c2ccc(OCC(N)=O)cc2)cc1F +CC1CN(C(=O)Nc2cc3c(cc2Cl)OCCCO3)CC(C)O1 +CCCN(C)C(=O)c1cc2ccc(OCC)cc2[nH]1 +Cc1cnc2c(c1)N(S(=O)(=O)c1ccc(F)cc1C)CCO2 +NS(=O)(=O)CC1CCCN1C(=O)NC1CCCCC1 +COc1cc2c(cc1OC)CN(Cc1nc(C)no1)CC2 +CNc1ccc(N(C)S(=O)(=O)c2ccccc2)c(C)c1 +COC(=O)C1CCN(C(=O)c2cccnc2SC)CC1 +CCc1noc(C)c1C(=O)OC(C)C(=O)NC1CCCCCC1 +COc1cc(C=Cc2nc(C#N)c(N(C)C)o2)cc(OC)c1OC +COc1ccc(CN(C)C(=O)CSc2nc(C)cs2)cc1 +CCCCCC(=O)Nc1ccc(C2OCC(=O)NC2CO)cc1 +Cn1ncc(C#N)c1NCc1ccc2[nH]ccc2c1 +c1ccc(-c2n[nH]c(C3CCCN(Cc4ccco4)C3)n2)cc1 +COc1cc(CNC(=O)c2ccc(OC(F)F)cc2)ccn1 +CC(=O)c1ccc(NC(=O)Cn2c(C)cc(C)c(C#N)c2=O)cc1 +Cc1sc2ncnc(N3CC4CC(O)C(O)CC4C3)c2c1C +CCN1CCOC(CCNC(=O)c2ccccc2-n2cncn2)C1 +Cc1occc1C(=O)Nc1ccc(OCC(=O)N(C)C)c(Cl)c1 +CCCC(=O)Oc1ccc2cc(C(=O)OCC)c(=O)oc2c1 +COc1ccc(OC)c(-c2nc3ccc(F)cn3c2CC#N)c1 +CCC(C)N1CNc2c(c(=O)[nH]c(=O)n2-c2ccc(C)c(C)c2)C1 +C#CCN1CCN(C(=O)NC(CC)C(=O)N2CCOCC2)CC1 +CCOc1ccc(NS(=O)(=O)c2ccccc2F)cc1CO +O=C(Nc1ccc2c(c1)N(C(=O)C1CC1)CC2)c1c(F)cccc1F +COCCOc1cccc(C2NC(=O)c3ccccc3N2)c1 +COc1cccc(NC(=O)COc2ccc(C)cc2-n2cnnc2)c1 +CC(C)n1ccnc1CN1CCCN(C(=O)c2cnn(C)c2)CC1 +CCOC(=O)c1sc2nc(C)nc(NCC3CCCO3)c2c1C +CC(=O)N1CCCC1C(=O)Nc1cccc(-c2ncc(C)o2)c1 +Cc1cccc(C)c1OC1CN(C(=O)c2ccc3nccn3c2)C1 +Oc1cccc(-c2nccn2CCCOc2cccnc2)c1 +CCOc1ccccc1NC(=O)CCNC(=O)C1CC1C +COC(=O)Nc1ccc(NC(=O)C2CCCC2)cc1F +Cc1nc2cc(NCc3c(C)n[nH]c3C)ccc2o1 +CNC(=O)c1cccc(CNC(=O)CCNC(N)=O)c1 +CCc1nc(-c2c(C)noc2C)ncc1Br +CCCC(C)NC(=O)C1CCCN(c2cc(C)nc3ncnn23)C1 +Cn1cc(CNC(=O)CCCNC(=O)C2CC2)cn1 +COc1cccc(C(=O)OCC(=O)NCC2CCCO2)c1 +CC(=O)Nc1ccc(OC(=O)C2(c3ccccc3)CCOCC2)cc1 +Cc1noc(C(C)OC(=O)c2cc3ccccc3s2)n1 +Cc1cc(F)ccc1NC(=O)C1CC1c1ccco1 +Cc1noc(C2CC3CN(C(=O)c4occc4C)CCC3O2)n1 +CC(C)n1nccc1NC(=O)CCCC(=O)c1ccc(F)cc1 +COC(=O)C(C)CS(=O)(=O)N1CCc2cc(F)ccc2C1 +O=C(Cn1cnc2ccc(Cl)cc2c1=O)NCC1CCCCC1 +Cc1c(CO)nnn1-c1nc2c(s1)CCCC2 +CC(C)C(NC(=O)NCc1ccc(-c2ccn[nH]2)cc1)c1ccccn1 +O=C(NCc1ccc(=O)[nH]c1)c1ccc(-c2cscn2)cc1 +CCOC(=O)C(O)(c1ccc(OC)cc1F)C(F)(F)F +Cc1cc(N2CCN(C(=O)NCCOc3ccccc3)CC2)ncn1 +O=C(c1ccccn1)N1CCN(C(=O)c2cc3ccoc3s2)CC1 +CCC(CC)C(=O)N1CCc2ccc(C(O)CC)cc2C1 +Cc1cc(CNC(=O)c2cccc(-c3ccc(O)cc3)c2)n(C)n1 +COC(=O)CCC(=O)c1cc2c(cc1Cl)OCCO2 +Cc1nn(C)c(=O)c(C(=O)NC(C)Cc2cccs2)c1C +CC1CCc2sc(C(=O)NC(C)(C)C#N)cc2C1 +COc1ccc(Cl)cc1C(=O)Nc1cccc(CO)c1 +CC(=O)c1c[nH]c(C(=O)NCC23CC4CC(CC(C4)C2)C3)c1 +Cc1ccc(C(C)NC(=O)NCCCNC(=O)C(C)C)cc1F +CCc1cccc(NC(=O)CCn2cnc3c(cnn3C)c2=O)c1 +Cc1ccc(C(=O)N(C)Cc2ccccc2OC(F)(F)F)c(=O)[nH]1 +CN(C)c1ncccc1C(=O)N1CCCN(Cc2nccn2C)CC1 +CC(NC(=O)c1csnn1)c1ccc(F)c(Cl)c1 +O=C(c1cccc(F)c1)N1CCC2(CC1)CCN(CC1CC1)C2=O +CN(C)S(=O)(=O)c1ccc(N)c(Br)c1 +Nc1nc(C2CC2)ncc1C(=O)Nc1cccnc1 +O=C(C1COCCO1)N1CCN(c2ncc(Cl)cc2Cl)CC1 +Clc1ccc(-n2nnnc2SCCCN2CCOCC2)cc1 +Cc1ncoc1C(=O)N1CCC2(CC(OCc3ccncc3)CO2)C1 +OCCN1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 +COc1ccc(OCC2C3CCC(C3)N2S(=O)(=O)C(C)C)cc1 +COc1ccccc1CNC(=O)c1cc(Cl)c2c(c1)OCCO2 +O=C(NCCN1CCNC1=O)c1cc2cc(F)ccc2[nH]1 +CC(CNC(=O)NCCC1CCCCC1)N1CCOCC1 +COc1ccccc1C(=O)N1CCCC1c1ccco1 +CCc1onc(C)c1NC(=O)CCc1nc2c(C)cccc2[nH]1 +Cc1nc(-c2cccs2)sc1C(=O)NCCC(=O)N1CCCC1 +CCCNC(=O)CC1CSc2nc(C)c(CC)c(=O)n21 +Cc1noc(C)c1C(=O)NCc1ccc(CS(N)(=O)=O)cc1 +CCOC(=O)c1nnn(Cc2c(Cl)cccc2Cl)c1N +CCCC(=O)c1cc2c(cc1NC(=O)c1cccs1)OCCO2 +O=C(CNC(=O)c1ccsc1)Nc1nc2c(s1)CCC2 +COc1ccc(-c2nc3ccccc3n2CC(=O)NC2CC2)cc1 +COc1ccccc1C(=O)NCC(=O)Nc1c(C)cc(C)cc1C +Cc1ccc2ncc(C(=O)N(C)C3(C#N)CCC3)n2c1 +Cc1ccc(CC(=O)Oc2ccc(-c3ccc(C#N)cc3)cc2)cn1 +COc1ccc(C(C)=O)c(OCc2noc(-c3ccoc3)n2)c1 +CCNC(=O)c1nsc(C(=O)NCc2ccc(OCC)cc2)c1N +CC(NC(=O)C(C)(C)C)C(=O)Nc1ccc(OC(F)F)cc1 +Cc1cccc(OC(=O)Cn2c(=O)cnc3ccccc32)c1 +COc1ccc(Oc2cncc(C3CCCN3C(C)=O)n2)cc1 +COc1ccccc1OCC(=O)N1CCOC(c2ccc(F)cc2)C1 +Nc1ccc(F)c2c(C(=O)NC3CCCC3)nccc12 +COCc1ccccc1CNS(=O)(=O)c1ccc(C)c(F)c1 +O=C1OC(C(=O)Oc2ccc(F)cc2)Cc2ccccc21 +c1ccc(N2CCN(c3nc4ccccc4n4cnnc34)CC2)cc1 +CCC(NC(=O)Nc1nnc2ccccn12)c1cc(F)ccc1F +Cc1cc(C)n(-c2ccc(C(=O)NCCc3nccs3)cc2)n1 +CCOc1ccc(CC(=O)Nc2c3c(nn2C)CCC3)cc1 +COC(=O)c1ccc(C(=O)N(C)c2ccc(F)c(F)c2)o1 +O=C(NC=Cc1ccsc1)Nc1ccc(F)cc1 +O=C(Nc1ccc2ncccc2c1)c1cccnc1OCC(F)F +COC(C(=O)NCC1CCN(c2ccc(F)cc2)C1)c1ccccc1 +O=C(c1ccccn1)N1CCN(C(=O)c2cc3scnc3[nH]2)CC1 +Cn1c(CNc2cnn(-c3ccccc3F)c2)nc2ccccc21 +O=C(Cc1ccc(-n2cccn2)cc1)NC1CCC(CO)CC1 +CCc1sc(C(=O)N2CCN(c3cc(C#N)ccn3)CC2)cc1C +COC(=O)CCn1c(CO)nc2ccc(F)c(F)c21 +O=C(Cc1ccccc1F)NC(CN1CCOCC1)c1ccccc1 +Cc1ccc(C(=O)Nc2nc3ccc(N)cc3s2)cn1 +CCN(CC)C(=O)c1ccc(OCC(=O)Nc2ccccc2)cc1 +COC(=O)C1CC1C(=O)Nc1ccccc1C(=O)C(C)C +CC(=O)c1ccc(N2CCN(C(C)C(=O)NC(C)(C)C)CC2)cc1 +COC(=O)c1ccc(Cl)c(NC(=O)CC(C)C(N)=O)c1 +COc1ccc(-c2nnc(NC(=O)c3ccnn3C)o2)c(OC)c1 +C=CCSc1n[nH]c(=O)n1-c1ccc2c(c1)OCCO2 +CC1CCCC(NC(=O)Cn2nc(-n3cncn3)ccc2=O)C1C +CCc1ccc(OC)c(-c2cc(CO)c(=O)[nH]n2)c1 +O=C(NCc1ccccc1)c1snnc1-c1ccccc1 +Cc1ccccc1-c1nnn(CC(=O)Nc2ccc3c(c2)C(=O)OC3)n1 +CCCOc1ccc(NC(=O)c2ccco2)c(N)c1 +COc1ccc(CN(C)C(=O)CCn2ncc3ccc(C)cc32)cc1 +CC(CNC1=NS(=O)(=O)c2ccccc21)Nc1ccccc1 +CC(NC(N)=O)C(=O)NCc1ccccc1Cn1cccn1 +COc1ccc2[nH]cc(CCNC(=O)c3ccnn3C)c2c1 +O=C(Nc1ccc(Cl)cc1)C1CC(=O)N(C2CCCC2)C1 +Cc1ncc(-c2ccc(NC(=O)c3nccnc3N)cc2)o1 +O=C(CNC(=O)c1cccc(F)c1)Nc1ccc2c(c1)COC2 +Cn1c(=O)oc2cc(S(=O)(=O)N3CCc4ccccc4C3)ccc21 +Cc1csc(=O)n1CCC(=O)Oc1ccc2ccccc2c1 +CCC(CNC(=O)c1cnc2cc(C)nn2c1C)c1ccccc1 +CC(C)CCNC(=O)Nc1ccnc(C(=O)N(C)C)c1 +CCC(CCO)NC(=O)Nc1ccc(NC(=O)C2CC2)cc1 +O=C(Nc1ccccc1)c1cc(-c2ccccn2)[nH]n1 +Cc1cccc(C(=O)NCCCNS(C)(=O)=O)c1O +CCc1nnc(SCC(=O)N2CCCCC2)o1 +CC(=O)NCC1CCCN(C(=O)c2cnn(C)c2-n2cccc2)C1 +Cc1n[nH]c(C(=O)N2CCN(CC(C)O)CC2)c1Br +CCc1cc(=O)n2c(n1)SCC2CC(=O)N1CC(C)CC(C)C1 +CC1(C)CN(CC(=O)NCc2cc(Br)cs2)CCO1 +CC(C)OC(=O)c1nnn(Cc2ccc(Cl)cc2)c1N +COc1cc(C)c(S(=O)(=O)NC2(C#N)CCCC2)cc1C +CCNc1cc(C(=O)NCc2cnc(C)s2)ccn1 +Cn1cc2c3c(cccc31)CN(C(=O)c1cccc(Cl)c1)CC2 +CNC(=O)c1cc(NC(=O)c2cc(C)on2)ccc1F +CCOCCCC(=O)Nc1[nH]nc(C(F)(F)F)c1C +CC(CCc1ccccc1)CC(=O)N(C)C(C)CC#N +CCCNC(=O)CNS(=O)(=O)c1ccc(F)cc1 +Oc1cccc(CN2CCOC(c3cccc(Br)c3)C2)c1 +CC(C)=CCN1CCN(S(=O)(=O)N2CCOCC2)CC1 +Cc1ccc(C(=O)Nc2cc(N3CCCS3(=O)=O)ccc2C)cc1 +COc1cc(CNC(=O)Nc2ccnn2C2CCCCC2)ccn1 +C=CCCCN(C)C(=O)COc1ccc2ccc(=O)oc2c1 +COCc1cccc(CNC(=O)N2CC(C)CC(C)C2)c1 +COCCN1CCN(Cc2nc3ccsc3c(=O)[nH]2)CC1=O +C=CCNC(=O)CN(C)C(=O)c1c[nH]c2ccccc12 +CSc1ncccc1C(=O)OCC(=O)NCC(F)(F)F +COCc1cc(C(=O)Nc2cc(OC)cc(OC)c2)ccc1F +COc1ccc2c(c1)CN(Cc1nc3c(F)cccc3[nH]1)CC2 +COC(=O)CNC(=O)c1cc(C2CC2)nc2onc(C)c12 +CCOc1ccccc1NC(=O)NCc1ccnc(OC2CCC2)c1 +Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)CS3)cc1 +Cc1nc(CNc2nc3ccc(S(C)(=O)=O)cc3s2)cs1 +CCOc1nn(-c2ncc(C(F)(F)F)cc2Cl)c(=O)o1 +COC(=O)CCCC(=O)c1ccc2c(c1)N(C)CC(C)O2 +O=C(CCc1ccncc1)NC1CCOC1c1ccc(Cl)c(F)c1 +COc1cccc(C2NCCc3cc(F)cc(Cl)c32)n1 +Cc1nc(-n2[nH]c(C)c(CC(=O)N3CCCCC3)c2=O)sc1C +Cc1occc1CN(C)Cc1ccc(S(=O)(=O)C(F)F)cc1 +COc1ccc(OC)c(CCC(=O)N(C)Cc2nc(C)n[nH]2)c1 +CC(=O)Nc1cccc2c1ccn2CC(=O)Nc1ncccc1C +COc1cc(Cl)c(CNC(=O)c2ccccc2F)cc1OC +Cc1ccc(C)c(C(=O)N2CCN(Cc3cccs3)CC2)c1 +CCc1nnc(NC(=O)NC2CCN(c3ccccc3)C2=O)s1 +CC(NC(=O)c1nccn1-c1ccccn1)c1ccccc1 +CN(Cc1ccco1)C(=O)c1cccc(N(C)C)c1 +c1ccc(-n2nnnc2CSc2nnnn2C2CCCC2)cc1 +CCCc1nnc2sc(COc3ccccc3)nn12 +CCCS(=O)(=O)N(Cc1cnc2ccccn12)c1ccccc1 +CCOc1ncccc1-c1ccc(C(C)NC(C)=O)cc1 +COc1ccc(NC(=O)c2c(C)noc2-c2ccccc2)c(OC)c1 +O=C(NCc1ccnc(OC2CCCCC2)c1)C1CC=CC1 +Cc1ccc(C(=O)Nc2cccc(NC(=O)c3ccncc3)c2)s1 +COCCN(CCOC)C(=O)c1ccc(Cl)cc1Cl +CC(=O)NC(C)C(=O)Nc1ccc(Oc2cccnc2)c(C)c1 +COc1cc(C(N)C(=O)NC(C)C)cc(OC)c1OC +C#CCOC(=O)CCc1c(C)nn(CC(C)C)c1C +Cc1ccc(F)c(-n2nnnc2CN2CCc3cncnc3C2)c1 +O=c1cc(CSc2ncnc3ccccc23)nc2sccn12 +O=C(NCc1n[nH]c(=O)c2ccccc12)c1ccc(=O)[nH]c1 +O=C(NCC(O)COc1ccccc1)c1cc(C2CC2)[nH]n1 +CCc1nnc2n1CCN(C(=O)c1ccccc1Cc1ccccc1)C2 +O=C(NC(c1ccccc1)c1ccccn1)C1COc2ccccc2O1 +Cn1nccc1CCNC(=O)NCc1ccc(-c2cccnc2)cc1 +CCC(CC)C(=O)NCC(=O)c1ccc2c(c1)OCCCO2 +Cc1cn2nc(N3CCOC(Cn4cccn4)C3)sc2n1 +O=C(Nc1ccccc1O)C1CCN(C(=O)CC2CCCC2)CC1 +COc1cc(C)sc1C(=O)Nc1cccc(NC(=O)C(C)C)c1 +CCC(=O)NCC(=O)NCc1nc(-c2cccs2)no1 +COc1cc(NC(=O)N2CCCC2)ccc1NC(C)=O +CC(C)(C)c1ccc2c(c1)CCN2C(=O)c1cc(C(N)=O)c[nH]1 +CCN(CC(=O)Nc1c(C)nn(C)c1C)c1ccc(F)c(F)c1 +COCC(=O)N1CCN(c2ccc(C(=O)OC)cc2)CC1C +Cc1cc(C)c(C(=O)CSc2nnc3cc(C)nc(C)n23)c(C)c1 +CC(C)(CO)n1c(C(F)(F)F)nc2ccc(F)c(F)c21 +Cc1ccc(NS(=O)(=O)c2cn[nH]c2C)c(O)c1 +COc1ccccc1NC(=O)c1nc(-c2ccncc2)no1 +O=C(NCc1ccco1)c1cn(Cc2ccccc2)c2ncccc12 +Cc1ccc(CC(=O)Nc2cc(C(N)=O)cc(F)c2C)s1 +CC(=O)c1ccccc1NC(=O)C(C)OC(=O)c1cc(C)oc1C +COc1ccc(CNc2cnn(CC(F)(F)F)c2)cc1O +Cn1cc(CNC(=O)c2cccc(Br)c2)cn1 +CCS(=O)(=O)c1ccc(NC(=O)N(C)C(C)c2ccco2)cc1 +O=C1CN(C(=O)c2cnn(-c3ccccc3)c2-n2cccc2)CCN1 +COC(=O)CCC(=O)N1CCC(c2nc(C)no2)CC1 +COCC(C)NC(=O)C1(c2cc(-c3ccccc3F)on2)CC1 +COc1ccc2cc(CNC(=O)Nc3ccc(C(N)=O)cc3)ccc2c1 +Cc1ccn(CCC(=O)NC(C)Cc2ccco2)n1 +Cc1ccc(C(C)C)c2c1C(=O)C(CO)(CO)CCO2 +O=C(Nc1cccc(-c2cc[nH]n2)c1)c1cc(-c2ccco2)n[nH]1 +N#CCOc1cc(C(=O)NCc2cccnc2)ccc1N +NC(=O)C1CCN(C(=O)Nc2ccccc2F)C1 +Cc1ccsc1CCNC(=O)CC(C)n1cccn1 +CCCCNC(=O)Nc1ccc(C)c(NC(C)=O)c1 +Cc1cc(C)n2c(CNc3cnn(-c4ncccn4)c3)cnc2n1 +Cc1nn(C)c2c(=O)n(CC(=O)NCc3ccco3)nnc12 +CCC(C)NC(=O)CCNC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(NC(=O)CSc1nnc(-c2ccccc2)n1C)C1CC1 +COc1ccc(CC(=O)Nc2nnc(C(F)(F)F)s2)cc1 +CCOc1cc(OC)c(Br)cc1C(=O)CC +Cc1noc(C(C)NC(=O)CCOc2ccccc2)n1 +Cc1ccc2c(c1)nc(-c1ccccc1)c(=O)n2CCCO +C#Cc1cccc(NCC(=O)N(CC)CC(C)C#N)c1 +COCCN1CCN(C(=O)C2CCOc3ccccc32)CC1=O +COc1cc(C(=O)NC(C)CO)ccc1OCc1cscn1 +COc1cc(C#N)ccc1CNc1cccc(F)n1 +CC(C)n1ncc2cc(NC(=O)c3cnc4ccccc4n3)cnc21 +CCOC(=O)C1(NC(=O)CCc2cnn(C)c2)CCc2ccccc21 +CN(C)C(=O)Cn1c(=O)cc(C(F)(F)F)n2c3ccccc3nc12 +O=C(NCCc1cnn(-c2ccccc2)c1)c1cccc2ccnn12 +CC(=O)NCC1CCN(C(=O)CCC2CCCC2)CC1 +CCN(C(=O)CSc1nnc(-c2cccnc2)o1)c1ccccc1 +Cc1cccc(NC(=O)N2CCOC(c3nccs3)C2)n1 +COCC(NC(=O)C1(c2cccc(C(F)(F)F)c2)CC1)C(N)=O +CCSc1nnc(NC(=O)c2ccc(-n3nncc3C)cc2)s1 +CC(CCc1ccc(O)cc1)NC(=O)NCc1ccccc1F +Cc1nc2ccccc2n1CCOc1nnc(-c2ccccc2)o1 +CS(=O)c1nncn1Cc1sccc1Br +Cc1ccc(OCC(=O)N2CCc3cc(N)ccc32)c(C)c1 +COc1ccc(-c2cc(C(=O)NCC(C)C)n(C)n2)c(F)c1 +COCC(C)N(Cc1cccc(C)c1)C(=O)c1ccnn1C(F)F +COC(C)C(=O)NC(C)c1cccc(OCc2ccccn2)c1 +COc1ccc(NC(=O)COc2cn(C)c(C)cc2=O)cn1 +CC(C)c1ccc(-c2csc3nc(N)nn23)cc1 +CCOC(=O)c1c(NC(=O)c2cccc(C#N)c2)sc(C)c1C +Cc1ccsc1CNC(=O)C(C)CN(C)C(=O)OC(C)(C)C +CCOC(=O)C(C)N1CCC2(CCC1=O)CC(=O)c1ccccc1O2 +NC(=O)c1ccc(Cl)c(NC(=O)c2ccc3ccccc3c2)c1 +CCOc1ccc(-c2noc(CS(=O)(=O)c3ccccc3)n2)cc1 +CC(C)C(O)c1nccn1-c1ccccc1N(C)C +CCN(CCO)C(=O)c1cc(Br)c[nH]1 +Fc1cccc(-c2nccn2CCCc2ccncc2)c1F +Cc1ccccc1CNS(=O)(=O)c1ccc(Cl)cc1 +N#Cc1cccc(CNC(=O)c2c[nH]nc2-c2ccccc2F)c1 +CCc1nc(NC(=O)c2cccc(C#N)c2)sc1C +CN(C)S(=O)(=O)c1ccc(CCC(=O)N2CCCC2)cc1 +CC(=O)NCCNC(=O)N1CCC(COc2ccccc2)CC1 +CNc1sc(S(C)(=O)=O)nc1S(=O)(=O)c1ccc(C)cc1 +Cc1ccc(C2Oc3c(C(C)C)cc(N)cc3N(C)C2=O)cc1 +O=C(NCCNS(=O)(=O)c1ccc2oc(=O)ccc2c1)C1CC1 +COc1nc2nonc2nc1Nc1ccc(C)cc1 +CCc1ccc(-c2cn3c(nc4cc(N)ccc43)[nH]2)cc1 +CC(C)COc1ccc(CNC(=O)Cn2cnnn2)cc1 +Cc1ccc(C(=O)Nc2ccccc2)cc1NC(=O)NC1CC1 +CC(=O)N1CCCc2cc(NS(C)(=O)=O)ccc21 +COC(=O)N1CCC(NC(=O)CCc2ccc(OC)cc2)CC1 +CC(C)c1cc(NC(=O)c2cn(CC(=O)N(C)C)nn2)[nH]n1 +FC(F)(F)c1cccc(-c2cnnc(NCCn3ccnc3)n2)c1 +CC(=O)N(C)CC(=O)NCc1ccc(-c2ccc3c(c2)CCO3)cc1 +O=C(CCNS(=O)(=O)c1ccccc1)Nc1ccc(F)cc1 +CC(=O)c1c(C)n(CC(=O)NCC2CCCO2)c2ccccc12 +COc1ccc(C2Nc3ccc(Cl)cc3C(=O)N2C)cc1O +COc1ccc(C(=O)Nc2cc(C(C)(C)C)on2)cc1 +CCOC(=O)C1=C(C)C(S(=O)(=O)N2CCN(C)CC2)C(C)=N1 +CCOc1ccc(C(C#N)Cc2cccnc2)cc1 +CS(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +Cc1oc(-c2ccco2)nc1Cc1nc(-c2ccc(C#N)cn2)no1 +N#Cc1ccc(COC(=O)c2cccc(CN3CCCC3=O)c2)cc1 +CCCC(=O)Nc1ccc(OCC2CCCO2)cc1 +Cc1cnc(NC(=O)c2ccc3c(c2)OCCO3)s1 +NC(=O)COc1ccccc1C(=O)NCCc1ccc2c(c1)OCO2 +CC(=O)Nc1cccc(NC(=O)c2ccc(=O)[nH]c2)c1 +COCCNc1nc(-c2ccc(OC)cc2)c(C)cc1C#N +Cc1ccc(C)c(C(=O)Nc2ccc(S(=O)(=O)N(C)C)cc2)c1 +CCCCCc1nnc(NC(=O)c2cc(Br)c[nH]2)s1 +Cc1cnc(C(=O)NC2CCCN(C(=O)COC(C)C)CC2)cn1 +COC(=O)N1CCc2c(sc(NC(=O)C(C)C)c2C#N)C1 +Cn1cc(CCNC(=O)NC2CCCN(c3ccccc3F)C2)cn1 +COc1ccc2c(c1)C=C(CN(C)Cc1cnc3ccccn13)CO2 +CN(C)S(=O)(=O)N1CCN(C(=O)c2ccccc2Cl)CC1 +Cc1cccc(NC(=O)CCc2c(C)c3ccc(O)cc3oc2=O)n1 +O=C(c1cccnc1OCC(F)F)N1CCc2ccccc21 +CC1CCCC(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)C1 +COc1cccc(C(=O)N2CCCC(c3nccn3CC(N)=O)C2)c1 +Cc1cc(NC(=O)c2sc(C)nc2C)n(-c2ccc(Cl)cc2)n1 +CNC(=O)Cc1ccc(NC(=O)NCC2CCCC(C)C2)cc1 +Cc1ccc(C(=O)NCCNC(=O)C2CCCO2)cc1F +Cc1ccoc1C(=O)N1CCc2onc(COCC3CC3)c2C1 +CC(=O)Nc1cccc(N2C(=O)CCS2(=O)=O)c1 +CC(C)Oc1ccc(NC(=O)N2CC(C)OC(C)C2)c(F)c1 +CC(C)CNC(=O)CS(=O)(=O)c1nccs1 +C=CCCOC(=O)c1ccc(-n2cncn2)cc1C +COC(=O)Nc1cccc(C(=O)NC2CC2c2ccc(F)cc2)c1 +Fc1cncc(C2NCCc3cc4cc[nH]c4cc32)c1 +CNC(=O)c1cccc(NC(=O)c2c[nH]c3cccc(F)c23)c1C +COCCNc1nc(-c2c(COC)oc(C)c2C)cs1 +Cn1cnnc1C1CCN(C(=O)c2cc3cc(F)ccc3s2)CC1 +CC(=O)Nc1ccc(Nc2nn3c(nc4cc(C)ccc43)[nH]2)cc1 +CC(NC(=O)c1cc(-c2ccccc2)no1)c1ccccc1 +Cc1cc(OCC(CC#N)N2CCOCC2)ccc1Cl +CCOc1ncccc1C(=O)Nc1cnc2c(cnn2C(C)C)c1 +CCOC(=O)C(CC)N(C)Cc1cccc(C#N)c1 +CC(C)(C)NC(=O)CNC(=O)Nc1cccc(F)c1F +CC(=O)N1CCN(C(=O)C2CC(=O)N(c3cc(C)cc(C)c3)C2)CC1 +Cc1noc(NC(=O)CCc2nc(C(C)(C)C)no2)n1 +N#Cc1cccc(NC(=O)CNc2ccccc2Cl)c1 +O=C1c2ccccc2NC(c2csnn2)N1c1ccccc1 +Nc1c(Nc2cccc(Cl)c2Cl)ncnc1N1CCOCC1 +CN(Cc1cccc(C#N)c1)C(=O)NCC(F)(F)F +CC(C1CC1)N(CC(F)(F)F)C(=O)c1ccc(C#N)cc1 +CC(C(=O)Nc1ccc(Cl)cn1)c1cccs1 +CNC(=O)C1Cc2ccccc2CN1Cc1nc(C)no1 +CC(NC(=O)CCc1nc2ccccc2s1)c1ccncc1 +CC(C)(CNC(=O)c1ccc(S(C)(=O)=O)cc1)c1ccncc1 +CC(C)Oc1ccc(C#N)cc1NCc1nc(C(C)C)no1 +CC(C)(C)C(=O)NCCC(=O)Nc1cc(F)c(F)c(F)c1 +COc1ccc(NC(=O)c2cnn3c2CCCC3)cc1OC(C)C +CNS(=O)(=O)c1ccc(NC(=O)c2ccc3ccccc3n2)cc1 +Cc1cccc(CC(C)n2cnc3cc(Cl)ccc3c2=O)n1 +COC(=O)N1CCCN(C(=O)CCCOc2ccccc2F)CC1 +Cc1ccc(CN2CCc3nc(N4CCOCC4)ncc3C2)cc1 +CC(C)CC(NC(=O)c1ccc(=O)n(C)c1)c1cccs1 +Cc1nc2cccc(C(=O)NC3CCCCC3)c2o1 +Cn1nnnc1NC(=O)Cn1c(=O)oc2ccc(Cl)cc21 +COc1ccc(C(=O)CCc2nc(C)cs2)c(OC)c1 +CCc1cc(N)cc(C)c1NC(=O)c1cccc(C)c1OC +Nc1cccc(NC(=O)NCCS(N)(=O)=O)c1 +Cc1sc2c(c1C)C(=O)NC(c1ccc(O)cc1)N2 +C#CCNC(=O)CSc1nnc(-c2ccccc2)n1-c1ccccc1 +CCN1CCN(Cc2nc(-c3cc4ccccc4o3)no2)C(=O)C1=O +Cc1cnc(CCN(C)C(=O)C2C3CCCC32)s1 +CC(=O)c1ccc(OCC(=O)N2CCCC2)cc1O +CCOC(CC)C(=O)NCc1cc(F)ccc1Br +CN(Cc1ccccc1)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +Cc1cnc(C(=O)NCc2ccc(-n3cncn3)nc2)cn1 +COc1cccc(C(=O)N2CCC(CC(N)=O)CC2)c1 +NC(=O)C1Cc2ccccc2N1C(=O)C1COc2ccc(F)cc2C1 +COc1ccc(C(=O)CNC(=O)c2ccco2)cc1C(C)C +CCC(C)Oc1ccc(NC(=O)c2csnn2)cc1 +Cc1ccc(C(=O)NCc2ccc(C(C)(C)C)cc2)c(=O)[nH]1 +COc1ccccc1C(C)(O)CNCc1ccccn1 +Cc1cc(NC(=O)NCCNc2ncc(Cl)cc2Cl)n(C)n1 +Cc1ccc(-c2nnn(CC(=O)Nn3cnc4ccccc43)n2)cc1 +CN(CC(N)=O)C(=O)c1csc(-c2ccc(Cl)cc2)n1 +Cc1cc(CN2CCOC3C(Oc4ccccn4)CCC32)no1 +CCOC(=O)N1CCN(c2ncc(Cl)cc2N)CC1 +CCN(C(=O)C(C)Sc1nnnn1C)c1ccccc1 +CCOC(=O)CCC(C)NC(=O)N1CCCC1c1ccco1 +CCc1cc(NCc2cc(OC)cc(OC)c2)n2ncnc2n1 +CCCOc1cc2c(cc1OC)CCNC2c1ncccn1 +Cc1cnc(C(=O)N2CC=C(c3c[nH]c4ccccc34)CC2)cn1 +Cc1ccc(NC(=O)NCC(=O)NC2CC2)cc1Br +Cc1nc2cc(COC(=O)CNC(C)C)ccc2n1C +Fc1cccc(F)c1-c1ccc(CN2CCC3(C2)OCCO3)o1 +CC(=O)N(C)Cc1cccc(NC(=O)NCc2ccnn2C)c1 +O=C(CN1C(=O)C2CCCN2c2ncccc21)NC1CC1 +Cc1cc(-c2cc(C(=O)N(C)C)c3cnn(C(C)C)c3n2)c(C)o1 +O=C(COC(=O)c1cc(F)ccc1F)Nc1ccccc1 +Cc1nn(C)c(C)c1CNC(=O)Nc1cccc(Cl)c1Cl +O=C(NC(c1cccs1)C1CCCC1)C1CCOC1 +COc1ccccc1CN(C)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CSc1ccccc1C(=O)OCC(=O)Nc1ccc2c(c1)OCO2 +O=C(NC1CC1)c1cc(-c2cc[nH]n2)n2ccccc12 +CCN1CC(C(=O)NCc2cc(F)ccc2C(F)(F)F)CC1=O +O=C(c1cnc(C2CCCO2)s1)N1CCCc2cc(Cl)ccc21 +Cc1cc2cc(C(=O)N3CCC(C#N)(c4ccccc4)CC3)ccc2o1 +CCOCCN(CC)C(=O)c1cccc(-n2cccn2)n1 +COc1ccc(C(=O)Nc2c[nH]nc2C)c(OC)c1 +CCOC(=O)C(CC)N1C(=O)COc2ccc(C(=O)CC)cc21 +O=C(NCc1ccc(F)cc1)Nc1ccc(Oc2cccnc2)nc1 +CC(=O)Nc1ccc(CN2CCC(c3nc4ccccc4n3C)C2)cc1 +CCS(=O)(=O)N1CCc2ncnc(-c3ccsc3)c2CC1 +Cc1noc(C2CCCN2C(=O)C2CC=CCC2)n1 +CC(O)(CNC(=O)NCc1nc2ccccc2s1)c1ccsc1 +Cc1cc(C)n(CCC(=O)NCCc2ccccc2)n1 +CCc1cccc(C)c1NCC(=O)c1ccc(OC)cc1OC +O=C(c1cccc(F)c1)N(Cc1ccncc1)Cc1cccnc1 +CCCC1CN(C(=O)C(C2CC2)C2CC2)CCO1 +Cc1cc(Oc2ncnc(NCC3CCCO3)c2N)ccc1Cl +Cc1cc(F)ccc1NS(=O)(=O)c1ccc2c(c1)OCCCO2 +O=C(Cc1ccc(OC(F)(F)F)cc1)N1CCC2(CC1)OCCO2 +COc1cc(CN(C)Cc2nccs2)cc2c1OCO2 +CCCCN(C)C(=O)c1cc2c(=O)n3cc(C)ccc3nc2n1C +COc1ccc2cc(CN(C)CCc3ccncc3)c(=O)[nH]c2c1 +CCCc1nnc(NC(=O)CCn2cncn2)s1 +COc1cccc(CC(=O)Nc2c(C)cccc2C(C)C)c1 +CC(C)NS(=O)(=O)c1cc(C(=O)NCCO)ccc1F +CN(Cc1ccccc1C(F)(F)F)C(=O)c1ccc[nH]c1=O +Cc1ccc(NC(=O)Cc2nc(-c3ccccc3)oc2C)nc1 +COc1ccc(NC(=O)C2CC2c2ccccc2F)c(OC)c1 +COC(=O)N1CCC(NC(=O)c2cnn[nH]2)CC1 +CCOc1ccc(C(=O)NCC2CCN(C(=O)OC)CC2)cc1 +Cc1ccc2cc(C(=O)Nc3ccc(F)c(C(N)=O)c3)[nH]c2c1 +Brc1ccccc1OCCN1CCOC2(CCC2)C1 +Nc1cccc(C(=O)NCc2ccncc2Cl)c1 +Cc1nc(C)c(C(=O)N2CCC(n3c(=O)[nH]c4ccccc43)CC2)o1 +COc1ccc(C(=O)N2CCC(CN3CC(C)OC(C)C3)CC2)cc1 +O=C(NC(COc1ccccc1)c1ccccc1)C1COCCO1 +CCN1C(=O)Cc2cc(C(=O)NCCC3=CCCCC3)ccc21 +CCCc1nc2cc(C)cnc2n1CCCOc1cccc(N)c1 +CN(CC(=O)NC(C)(C)C)C(=O)c1ccccc1Cl +N#Cc1ccc(C(=O)NC2CCCN(Cc3ccccc3)C2=O)cc1 +CCc1nc(CN2CCN(CC3=Cc4ccccc4OC3)CC2)no1 +C=CCSc1nnc2nc3[nH]c4ccccc4c3nn12 +O=C(c1ccc(Cl)c(Cl)c1)N1CCC(F)(CO)CC1 +CN(C(=O)c1ccn(C2CCCC2)n1)c1ccc2c(c1)OCO2 +CCCCC(=O)N(C)Cc1cc(C#CCO)cs1 +COc1cc2c(cc1OC)C1=NCN(CC(C)C)C(=O)C1=N2 +CCCOCCC(=O)N(C)C(C)c1cccc(N)c1 +CCOC(=O)N1CCN(C(=O)c2cc(F)ccc2N)CC1 +Cc1ccc(CC(=O)NCc2ccc(OCC(F)(F)F)nc2)cc1 +CCOc1ccc(Cl)cc1CN(C)C(=O)c1cn2cccnc2n1 +CNS(=O)(=O)c1ccc(C(=O)Nc2c[nH]nc2C)o1 +C#Cc1cccc(NC(C)c2ccc3c(c2)OCCO3)c1 +Cc1cc(C(=O)N(Cc2cccnc2)C2CC2)no1 +COc1ccc(OC)c(NC(=O)CC(C#N)C(C)C)c1 +NC(=O)c1ccc(NCc2ccc(F)cc2N)cc1 +COc1cc(C(=O)NCCNC(C)=O)cc(Cl)c1OC +CCC1C(=O)NCCN1C(=O)c1cc2c(C)nn(C)c2s1 +Cn1cccc1C1CCCCCN1C(=O)c1cccc(NC(N)=O)c1 +O=C(Nc1nc2ccccc2s1)c1nnn(-c2ccccc2)n1 +CCOc1cncc(N2CCN(Cc3nc(C)no3)CC2)n1 +CCn1c(=O)c2c(C)nc(N)nc2c2ccccc21 +CNC(=O)NCC(=O)Nc1cccc(-c2nnc3n2CCCCC3)c1 +CCCNC(=O)NCCN1CCCc2ccccc21 +N#Cc1cnn(-c2ccccc2)c1NC(=O)Cn1ccnc1 +COCc1cccc(C(=O)Nc2cccc(CS(N)(=O)=O)c2)c1 +CCCn1c(SCC(=O)c2cc(C)n(C3CC3)c2C)n[nH]c1=O +O=C(Nc1ccccc1F)c1ccc(S(=O)(=O)NC2CC2)cc1 +CC1CN(CC(=O)N(C)C(C)c2ccc(Cl)cc2)CC(C)O1 +Cc1onc(-c2ccccc2Cl)c1C(=O)N1CCCC(C(N)=O)C1 +COCCNc1c(-c2ccccc2)nc2sc(C(N)=O)c(C)n12 +COCc1nc(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)cs1 +CCOC(=O)c1cc(C(=O)Nc2ccc(OC)cc2)c(=O)[nH]c1C +O=C(COc1ccccc1Cl)Nc1nc2ncccc2o1 +Cc1cc(C(=O)N2CCC(C)Sc3ccccc32)no1 +CC1CCCCC1NC(=O)NCc1ccc(OCC(F)(F)F)nc1 +COc1cc(F)c(S(=O)(=O)N(C)CC(=O)N(C)C)cc1OC +Cc1csc(NC(=O)CNS(=O)(=O)c2cn(C)cn2)n1 +CC(NC(=O)c1ccc(F)cc1F)(C(N)=O)c1ccccc1 +CC(C)NC(=O)CCC(O)c1ccc2c(c1)OCCCO2 +Cc1oc(C2CCN(C(=O)C3CCCC3)CC2)nc1C(=O)N(C)C +O=C(NCC(F)(F)F)c1cccc2c1OCCO2 +CC(O)CNC(=O)c1cccc(Oc2cccc(C(F)(F)F)c2)c1 +COc1ccc(Cl)cc1NCCC(=O)NCC1CCC1 +Cc1nnc2sc(-c3ccccc3O)nn2c1=O +Cc1cc(NCc2cnnn2C)ccc1C(=O)OC(C)(C)C +CN(C)S(=O)(=O)c1ccccc1CNC(=O)c1ccccn1 +Cc1ccc(F)cc1S(=O)(=O)N1CCOCC1C1CC1 +CC(C)c1noc(COC2CCN(C(=O)c3cnccn3)CC2)n1 +CC(C)(C)n1cc(NCc2nc(-c3ccccc3)cs2)cn1 +O=C(Nc1nc[nH]n1)c1ccc(C(F)(F)F)nc1 +O=C(CNC(=O)c1cccs1)NCCc1cccc(Cl)c1 +CC(=O)Nc1cccc(C(=O)Nc2cc(C(C)(C)C)n[nH]2)c1 +CSc1ccc(C)c(C(=O)Nc2nc(C(C)=O)cs2)c1 +Cc1nc2cc(NC(=O)NCc3ccccc3-n3ccnc3)ccc2o1 +CC(=O)N(C)CC(=O)N1CCN(C(=O)Nc2ccc(F)cc2)CC1 +CC(C)n1nccc1NC(=O)CCC(=O)N1CCOCC1 +CCN(CC)C(=O)c1cc(C(N)=O)ncc1OC(C)C +Cc1ccc(C(=O)NCc2nnc(C3CC3)n2C2CC2)s1 +Cc1cccc(Nc2ncnc(-n3cnc4ccccc43)c2N)n1 +Cc1cccc(-c2nnc(COC(=O)c3ccncc3)o2)c1 +Cn1cc(C2CN(Cc3cnc4cnccn34)CCO2)cn1 +CCc1cc(C(=O)NCc2ccc(C)cc2C)[nH]n1 +Cc1nc(CN(C)C(=O)NCc2sccc2C)cs1 +C=CCC(NC(=O)Nc1ccc(S(C)(=O)=O)cc1)c1ccncc1 +C#CCN(C)C(CO)c1cccc(Br)c1 +COc1ccc(C(=O)Cn2cc(N)cn2)cc1C(C)(C)C +CN(C)c1ccccc1NS(=O)(=O)c1ccccc1F +CCOC(=O)c1csc(-c2ccc(OCC)c(N)c2)n1 +O=C(Nc1nnc(Cc2ccc(F)cc2)s1)c1ccccn1 +CC(C)c1cc(=O)[nH]c2cc(NC(=O)COc3ccccc3)ccc12 +COCc1ccc(C(=O)NC2CCc3c(F)cccc32)cc1 +O=C(NCCNS(=O)(=O)c1cccc(Cl)c1)C1CC1 +O=C(c1cc2ccccc2[nH]1)N1CCN(C(=O)c2cccs2)CC1 +O=C(c1ccccn1)N1CCCCC1c1nncn1CC1CC1 +COC(=O)CNc1ccc(Cl)cc1C(=O)OC +COc1ccc(NC(=O)CS(=O)c2ccc(F)cc2)cc1 +CN(C)c1ccc(-c2nnn(-c3cccc(O)c3)c2N)cc1 +Cc1cc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)no1 +Fc1ccc(Cl)c2c1CCNC2c1cnccn1 +O=C(NCc1ccoc1)Nc1ccccc1Br +COc1ccc(-c2cc(CO)nn2CCO)c(OC)c1 +COc1ccc(C(=O)Nc2nc3c(C)cccc3s2)cn1 +Cc1nnc(CSc2nnc(-c3ccc(C(C)(C)C)cc3)n2C)o1 +CC(C#N)CN1CCN(C(=O)c2ccc(Cl)cc2)CC1 +O=C(Nc1nnc(C2CC2)s1)c1ccc(NC(=O)C2CC2)cc1 +Cc1noc(-c2cccc(OCC(=O)Nc3ccccc3C)c2)n1 +CCc1ccc(CCC(=O)Nc2cc(S(C)(=O)=O)ccc2F)cc1 +O=C1OC(c2cccs2)c2cc3c(cc21)OCCO3 +O=C(NCC(=O)N1CCc2ccccc2C1)c1cnn2ncccc12 +COc1cc(CNC(=O)Nc2ccc(N(C)C(C)C)c(F)c2)ccn1 +Cc1ccc(C(=O)N2CCCN(c3ccccc3C#N)CC2)c(=O)[nH]1 +CC(Sc1nnc(C2CC2)n1C)C(=O)NCC1CCCO1 +CN1CC2(COCCN(C(=O)c3cccnc3)C2)OCC1=O +CC(=O)NCCNC(=O)N(C)C(C)c1ccccc1Cl +COc1ccc(C(=O)N(C)C(c2ccccc2)C(C)C)nn1 +COc1ccc(Cl)cc1CNc1ncnc2sccc12 +CCCNC(=O)c1ccc(CS(=O)c2ccccc2C)o1 +O=C(NC1CCCC(O)C1)c1cccc2ccccc12 +COc1ccsc1C(=O)Nc1nc(-c2cccnc2)cs1 +COCC1CCCCN1C(=O)Cc1c(C)nn(-c2ccccc2)c1C +N#Cc1ccccc1NCC(O)c1ccc(F)c(N)c1 +O=C(c1ccc(-n2ccnc2)nc1)N1CCCSc2ccccc21 +COc1ccc(C(O)c2ccc(F)cc2)c(F)c1 +COCCc1ncc(C(=O)NCc2ccc(C)cc2)c(N)n1 +CCc1nn2c(=O)cc(CN3CCc4sccc4C3)nc2s1 +CCOC(=O)c1n[nH]c2c1CCc1c-2c(C2CC2)nn1C +CCCCCNC(=O)c1cc(=O)c2ccccc2o1 +O=C(c1nc2ncccn2n1)N(Cc1ccccc1)Cc1ccccc1 +O=c1oc(-c2cccs2)nn1CCOc1ccccc1 +COc1ccc2c(cnn2CCC(=O)Nc2ccccc2)c1 +CCc1oc(C(F)(F)F)cc1-c1csc(NC)n1 +CCNc1nnc(Sc2nccnc2C#N)s1 +C=CCn1cc(CN2CC=C(n3c(=O)[nH]c4ccccc43)CC2)c(C)n1 +Cc1cc(C(=O)Nc2nnc(-c3ccc4c(c3)OCO4)o2)nn1C +COc1ccc(OC)c(NC(=O)CNc2cccc(C(C)=O)c2)c1 +O=C(NCCc1c[nH]c2ccccc12)c1cnc2ccccc2n1 +CC1CCCC(CNC(=O)c2ccc(-n3cncn3)cc2)C1 +COc1c(C)cnc(CN(C)C(=O)c2ccc3c(c2)nnn3C)c1C +CC(Cc1ccc(O)cc1)NC(=O)NCCCN1CCCC1=O +O=C(NCCc1cccs1)C1CC(=O)N(Cc2ccccn2)C1 +Cn1c(=O)[nH]c(=O)c2c1nc(N)n2Cc1ccc(F)cc1 +CN(CC(=O)NCC1CCCCO1)S(C)(=O)=O +CCCOc1cc2c(cc1OC)C(c1cnccn1)NCC2 +O=C(Nc1nncs1)c1ccc(S(=O)(=O)N2CCCC2)cc1 +Nc1cc(S(N)(=O)=O)ccc1N1CCCCC1 +Cc1csc(-c2cccc(CNS(=O)(=O)c3ccccc3)c2)n1 +O=S(=O)(Cc1cccc(Cl)c1)NCCC(O)c1ccccc1 +Cn1ccc(C(=O)NCC(O)c2cccc(Cl)c2)cc1=O +Cc1nc(Cn2cnc3scc(-c4ccccc4)c3c2=O)no1 +Cn1ncc2c(Sc3cccc4ccccc34)ncnc21 +CC1CN(C(=O)Nc2ccccc2Br)CCO1 +CCOC(=O)c1cccc(NS(=O)(=O)c2cn(C)cn2)c1 +CCCNC(=O)c1c(NC(=O)c2c(F)cccc2F)cnn1C +C=CCNC(=O)CN1CCc2nc(NC(=O)OC)sc2C1 +CC(=O)c1cnc(-c2cnoc2)n1Cc1ccccc1 +O=C(COc1ccccc1)NCC(=O)c1ccccc1 +CN(C)C(=O)c1ccc(Cl)cc1NC(=O)NCCO +COc1ccnc(NC(=O)c2cc3c(s2)CCOC3)c1 +COc1ccccc1C(C)NC1CCCN(Cc2ccccc2)C1=O +C=CCCC(=O)Nc1ccccc1SCCC#N +O=C(NCc1ccccc1)c1ccc2[nH]ccc2n1 +Cc1ccc(-c2csc3nc4n(c(=O)c23)CCC4)cc1 +CCn1nnnc1SCCSc1nnnn1CC +c1cc(CN2CCN(Cc3cnc4ccsc4c3)CC2)ccn1 +CCC(=O)Oc1ccc(C(=O)Nc2ccc(OC)c(O)c2)cc1 +O=S(=O)(NCC1CCOC1)c1ccc(F)cc1Br +O=C1CN(C(=O)Nc2ccn(-c3ncccc3Cl)n2)CCN1 +COC(=O)CNC(=O)C1CCCCN1C(=O)OC(C)(C)C +N#CCCN(CC=Cc1ccccc1)Cc1cccnc1 +COCCOc1ccc(-c2cc(=O)[nH]c(=O)[nH]2)cc1 +CCc1cc2c(=O)n(CCCOc3cccc(N)c3)cnc2s1 +Cc1ccc(S(=O)(=O)CCC(=O)Nc2cccc(C(N)=O)c2)cc1 +O=C(NCCc1ccccc1F)N1CCCC(CN2CCOCC2)C1 +COC(=O)c1ccccc1NC(=O)c1cccc(NS(C)(=O)=O)c1 +CC(=O)c1ccc(NC(=O)NCc2ncccc2C)cc1C +CC1CCN(c2nc3c(cc2C#N)CCCC3)CC1 +CC(C)CC(O)c1cc(F)c2c(c1)C(C)C(=O)N2 +O=C(NCCCN1CCc2ccccc21)NCc1ccccc1 +O=C(CCOc1cccc(Cl)c1)N1CCCC(O)C1 +O=C(Nc1cccnc1)C1CC(=O)N(Cc2ccccc2Cl)C1 +Cc1nc(C(=O)NCc2ccccc2OC(C)C)cs1 +c1ccc(OC2CCC3C2OCCN3Cc2cccs2)nc1 +Cc1cc(C(C)NC(=O)NCCC(=O)N2CCCC2)c(C)o1 +COc1ccccc1S(=O)(=O)Nc1ccc(Cn2cncn2)cc1 +CS(=O)(=O)NCCNc1nc2cccc(Cl)c2s1 +CC(C)C(OC(=O)c1cc[nH]n1)C(=O)N1CCc2ccccc2C1 +Cc1cc(C)n(CC2CN(Cc3cnc(C)s3)CCO2)n1 +Cc1cc(OCCN2CC(CO)CC2=O)ccc1Cl +FC(F)(F)c1cc(NC2CCOCC2)n2ncnc2n1 +COc1cc(CC(=O)Nc2ncccc2C)cc(OC)c1OC +Cc1ccc(C(=O)Nc2ccc(-n3ccnc3)cc2)cc1 +Cc1cc(NC(=O)C2CC=CCC2)ccc1C(=O)N(C)C +Cc1cc(C(=O)Nc2ccccc2N2CCOCC2)c(C)o1 +CC(Cn1cccn1)NC(=O)c1ccc(N2CCCC2=O)cc1 +CCN1C(=O)C(C)(C(=O)NCCCO)Sc2ccccc21 +CCCCNC(=O)NCc1ncc(-c2ccccc2)o1 +CC(C)CNC(=O)CS(=O)(=O)c1ncccc1Cl +N#Cc1cccc(C(=O)N2CCN(c3cnccn3)CC2)c1 +CCN(CC(F)(F)F)C(=O)c1n[nH]c2ccccc12 +O=C(NCC1(C2CC2)CCC1)C1CC(=O)N(CC(F)(F)F)C1 +CCNC(=O)Nc1ccccc1OCCCOC +CC1Oc2ccc(NC(=O)c3cccc(OC(F)F)c3)cc2NC1=O +O=C(Cc1cc2ccccc2[nH]c1=O)OCc1ccccc1 +Cc1nc(N(C)C)nc2c1COCC21CCN(C(=O)NCC(C)C)C1 +Cc1cccc(CC(=O)NCCc2cc(C)no2)c1 +Cn1cccc1C(=O)N1CCC2(CC1)C(=O)Nc1ccccc12 +COCC(=O)N1CCC(C(=O)c2cnn(-c3ccccc3)c2N)C1 +Cc1cc(NC(=O)COc2c(C)nn(C)c2C)c2ncccc2c1 +CCc1nnc(CN(CC)C(=O)c2cn(-c3ccccc3)nn2)o1 +N#Cc1ccccc1OCc1nnnn1Cc1ccccc1 +CCCn1c(N)c(NC(=O)C2CC3CCC2C3)c(=O)n(CCC)c1=O +CCCNC(=O)c1cc(N(C)S(=O)(=O)c2ccc(C)cc2)ccn1 +CCN(CC)S(=O)(=O)c1cccc(C(=O)Nc2ccccc2C)c1 +COc1ccc(C(=O)N2CCN(c3ncccn3)CC2)c(F)c1 +CC(=Cc1ccccc1)c1nnc(-c2nonc2N)o1 +Cc1c(C(=O)N(C)C(C)Cc2ccc(Cl)cc2)cnn1C +COC(C)c1cccc(-c2ccc3nc(CO)[nH]c3c2)c1 +O=S(=O)(NCC(O)Cc1ccccc1)c1cccc(F)c1 +CCc1onc(C)c1NC(=O)NC1CCCCCC1 +Cc1cccc(-n2nnnc2SCC(O)CO)c1 +O=C1CCN(S(=O)(=O)c2ccccc2C(F)(F)F)CCN1 +Cc1cc(C)n(-c2ccc(C(=O)OCc3scnc3C)cn2)n1 +CC(C)(C)c1nnc(NC(=O)C2COc3ccc(F)cc3C2)s1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NC(C)c1ccncc1)O2 +CC(C)(C)Oc1cc(CNC(=O)C2(c3ccc(F)cc3)CC2)ccn1 +CCc1ccccc1NC(=O)NCCCN1CC(C)OC(C)C1 +Cc1cc(C(=O)N2CCCN(C(=O)c3cccc(Cl)c3)CC2)on1 +CCc1ccccc1OCC(=O)NC1CCCNC1=O +N#Cc1c(Cl)cccc1NCc1ccccc1N +Cc1cc(C(=O)Nc2cc(C(C)(C)C)on2)cs1 +CCN(CC)C(=O)CCC(=O)N1CCOc2cc(F)ccc21 +COc1c(C)cc(CN(C)C(=O)CCC2CCCO2)cc1C +Cc1cc(Br)ccc1NC(=O)NCC1CN(C)CCO1 +CCCSc1nc(N)c(C(=O)Nc2ccccc2)cc1C#N +Cc1ccc(C(=O)Nc2ccc3c(C)cc(=O)[nH]c3c2)cc1 +CCN(Cc1ccoc1)C(=O)Nc1cc(F)c(OC)cc1OC +Cc1cc(=O)c(C(=O)NC(C)(C)c2nc(C(F)(F)F)cs2)c[nH]1 +COc1ccc(NC(=O)Cn2c(C)nc3ccccc32)cc1OC +N#CC(C(=O)c1cnn(-c2ccccc2)c1)c1nnc2n1CCCCC2 +Cc1cc(C)c(C#N)c(SCC(=O)NCCc2cccs2)n1 +CCNC(=O)c1ccc(CNC(=O)NCc2ccco2)cc1 +Cn1cnc2cc(C(=O)OC3CCCC3n3cccn3)ccc21 +CCNC(=O)NCCCc1nn(-c2ccccc2)c(N)c1C#N +NC(=O)CCNC(=O)c1cccc(NC(=O)c2ccncc2F)c1 +CCc1nc2c(sc3nc4c(cc32)COC(C)(C)C4)c(=O)o1 +CC(C)(O)C1CCN(c2ncnc3[nH]ccc23)CC1 +Cc1noc(C2CCC3(CCN(C(=O)c4cocn4)CC3)O2)n1 +CCN(Cc1cnc2ccccn12)S(=O)(=O)c1ccc(C)cc1C +C=CCn1nnc(NC(=O)COc2cc(C)ccc2C(C)C)n1 +O=C(COc1coc(CO)cc1=O)Nc1ccccc1 +CCOc1ccc(N(CCC#N)C(=O)Cc2ccc(F)c(F)c2)cc1 +Nc1cc(F)cc2c1CCNC2Cc1cccnc1 +O=C(NC1CCN(CC(F)(F)F)C1)N1CCOCC1C1CC1 +COc1cccc2[nH]c3c(N4CCCC4)ncnc3c12 +CC(C)OCCN1CCN(C(=O)c2ccc3[nH]ccc3c2)CC1 +CC(=O)Nc1ccc(CN2CCOC(c3nc(C)cs3)C2)cc1 +Cc1cc(C(=O)Nc2ccc(C)c3ncccc23)ccc1-n1cnnn1 +COC(=O)C1CC1C(=O)OC(c1ccccc1)c1cccnc1 +COc1ccc(C2c3c(C)n[nH]c3Nc3[nH]c(=O)[nH]c(=O)c32)cc1O +N#CC(C(=O)C1CC=CC1)c1nc(-c2ccc(Cl)cc2)cs1 +Cc1cccc(NC(=O)C(C)Sc2nc3nc(C)cc(C)n3n2)c1 +CC(=O)NC(CC(=O)Nc1ccc(-n2ccnc2)nc1)c1ccccc1 +O=C(CSc1cccc(F)c1)Nc1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)c2ccc(=O)n(Cc3ccccc3)n2)cc1F +O=C(CS(=O)(=O)c1ccc(F)c(F)c1)Nc1cc(F)ccc1F +COc1ccc(Br)cc1NC(=O)NCc1ccncc1 +Nc1ccc(F)cc1C(=O)NCCc1ccc(Cl)cc1 +CC(NC(=O)CCc1nc(C(C)(C)C)no1)c1cccs1 +NC(=O)COC(=O)c1ccc(-n2ccc(C(F)(F)F)n2)cc1 +CN(CCc1ccncc1)S(=O)(=O)c1ccc(N)cc1 +CCC1CCCC(NC(=O)NC(CCO)c2ccccc2)C1 +COC(=O)c1cc(-c2ccc(O)c(Cl)c2Cl)on1 +O=C(CCc1nc(-c2ccccc2)no1)NCCc1cccs1 +CC(CC1CCCC1)C(=O)NCc1ccc(C#N)cc1 +COc1ccc(-c2nn3c(C(F)(F)F)nnc3s2)cc1N +COc1ccc(CC(=O)c2c(O)cc(OC)cc2OC)cc1 +CC(C)(C)C(C#N)NC(=O)c1ccc(Cl)cn1 +O=S(=O)(Cc1c(F)cccc1Cl)N1CCCCCC1 +CCc1cc(C(=O)Nc2ccc(-c3csnn3)cc2)[nH]n1 +COc1ccc(C(O)Cn2cc(N)cn2)c(C)c1C +Cc1cc(C(=O)N2CC3CCC2CN(C(=O)N(C)C)C3)no1 +N#Cc1cccc(CNc2ccc(C#N)c(Cl)c2)c1 +O=C1COc2cc(C(=O)Nc3cnccc3-n3ccnc3)ccc2N1 +COC(=O)c1cc(NCC(=O)Nc2ccccc2OC)ccc1F +CCn1ncc(C(=O)N(Cc2ccsc2)C2CC2)c1C +Cc1c(N)cccc1CS(=O)(=O)c1cccc(Cl)c1 +N#Cc1ccc(NC(=O)COC(=O)c2ccc(F)cc2)cc1 +CC1CCN(C(=O)c2ccc3c(=O)n4c(nc3c2)CCCC4)CC1 +COC(=O)C1Cc2ccccc2CN1C(=O)c1ccc(F)cc1Cl +COc1cc(C(=O)c2cncn2C)cc(OC)c1OC +Cc1cc(C(=O)OCc2cn(-c3ccc(Cl)cc3)nn2)nn1C +Cc1cc(C(=O)Nc2ccccc2-n2cnnn2)c(C)o1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cccc2ccccc12 +N#Cc1cccc(NC(=O)CCCC(=O)Nc2cccc(C#N)c2)c1 +COc1cccc(-c2nnn(Cc3ccc(C#N)cc3)n2)c1 +C=CCN1C(=O)CCCC12CCCN(C(=O)c1ccncc1F)C2 +O=C1OC(COCc2ccccc2)CC1OCc1ccccc1 +Cc1ccccc1CC(=O)N1CCC(CCC(=O)NC2CC2)CC1 +CC(C)c1nc(Cn2cnc3sccc3c2=O)cs1 +Cc1cc(CNCC(=O)NC(C)(C)C)ccc1F +O=C1CCC2CN(c3nccs3)CCC2N1CCc1cccs1 +Cc1noc(C)c1CN(C)C(=O)c1cnn(Cc2ccccc2)c1 +Cc1ccccc1C(=O)NCCn1ccc(-c2ccncc2)n1 +CN(CCN(C)C(=O)C1CC12CCOCC2)C(=O)OC(C)(C)C +CCN(CC)C(=O)COc1ccc(C2OCCCO2)cc1N +COc1ccc2c(=O)cc(-c3cc(OC)c(OC)c(OC)c3)oc2c1 +CN(C(=O)CSc1nc2c(cc1C#N)CCCC2)C1CC1 +c1cnn(Cc2nc(C3CCOC3)nn2C2CCCCC2)n1 +CC(NC(=O)c1ccoc1)C(=O)Nc1ccc2cn[nH]c2c1 +Cc1cc(Cl)ccc1NC(=O)CSc1nnc(C)n1C +Cc1nc(C)c(C(=O)NCc2cnc(OCC(C)C)c(Cl)c2)o1 +Cc1c2c(cc3c4c(c(=O)oc13)CCC4)CN(C(C)C)CO2 +COc1ccc(-c2cc(NCc3cccnc3)nc3[nH]ccc23)nn1 +COc1ccccc1Oc1ccc(CNC(=O)CC#N)cc1 +O=S(=O)(NCC1CCCO1)c1cccc(F)c1 +CN(Cc1cccc(C#N)c1)C(=O)CCCn1cncn1 +CN(CCO)C(=O)NCc1ccnc(OC(C)(C)C)c1 +COC(=O)C(CC(C)C)NS(=O)(=O)c1cc(C#N)ccc1C +COC1(CNC(=O)Nc2cnccc2C)CCOCC1 +Cc1cc(C(=O)CSc2nnnn2C2CCCC2)c(C)s1 +CC(C)Oc1ncc(C(=O)N2CCOCC2(C)C)cc1Cl +CCN(CC)C(=O)c1cc(-c2ccc(O)cc2)on1 +COC(=O)C(C)n1c(-c2ccncc2)nc2cccnc21 +Cc1cc(C(=O)N2CCN(CC(=O)Nc3cccc(F)c3)CC2)on1 +Cc1nc(CNC(=O)c2c(C)oc(C)c2C)c(C)s1 +O=S(=O)(c1cccc2nonc12)n1cccn1 +CCSc1cc(C(=O)NCc2ccc(OC)c(O)c2)ccn1 +N#Cc1ccc(CNC(=O)c2sccc2OC(F)F)cc1 +CC(C)c1noc2nc(C3CC3)cc(-c3nc(-c4ccncc4)no3)c12 +CCOC(=O)CNC(=O)c1n[nH]c2ccc(N)cc12 +CC(=O)c1ccc(OCCCC(=O)N2CCC(O)C2)cc1 +CC1(NC(=O)CCC(=O)Nc2nccs2)Cc2ccccc2C1 +CC(=O)Nc1ccc(OC(=O)CSc2nc3ccccc3o2)cc1 +Cc1cc(C(=O)NC(c2ccc(Cl)cc2)c2noc(C)n2)on1 +O=C1CCc2cc(NC(=O)c3ccccc3Cl)ccc2N1 +Cc1nc2cc(NC(=O)c3cccc(C#N)c3)ccc2o1 +CC(Nc1cnn(-c2ccccc2F)c1)C(=O)NC(C)(C)C +Cc1cccc(NC(=O)CS(=O)(=O)c2ccccc2F)c1C +Cc1csc(NC(=O)NCCNC(=O)OC(C)(C)C)n1 +CC(NC(=O)c1csc2c1CCCC2)c1nnc2n1CCCCC2 +O=S(=O)(Cc1ccc(F)cc1)NCCN1CCOCC1 +CC(C)Cn1c(SCCCO)nnc1N1CCOCC1 +Cc1ccc(-c2nc(C)c(C(=O)OCc3ccccn3)s2)o1 +CCCN(C1CC1)S(=O)(=O)c1ccc(CC)c(N)c1 +NC1=NC(=O)C2C(=N1)NC(=O)CC2c1ccc(O)cc1 +CCc1nsc(N2CCN(Cc3cn(C)nc3C)CC2)n1 +CC(=O)N1CCC2(CC1)CN(c1ncccn1)CC21CCN(C)C1=O +COc1ccc(CNc2cccnc2OC)cc1F +CCCC(=O)Nc1ccc2oc(-c3cccnc3)nc2c1 +CC(=O)N(C)Cc1cccc(NC(=O)NC(C)c2nccs2)c1 +OC1c2ccccc2CC1Sc1nnc2[nH]c3ccccc3n12 +Cc1ccc2c(C(=O)NCCN3CCOCC3)nccc2c1N +CCc1nc(CNc2cccc(C(=O)N3CCOCC3)c2)no1 +Cc1cc(C)c(NC(=O)C(C)Oc2ccccc2C#N)c(C)c1 +COc1ccc(OC)c(-c2csc(NC(=O)C3CCCO3)n2)c1 +Cc1cn(CC(=O)N(C)CCOCC2CC2)c2ccccc12 +CCN1CCN(CCOc2cccc(Cl)c2)C(=O)C1=O +Nc1ncn(CC(=O)Nc2ccc(OC(F)(F)F)cc2)n1 +Cc1ccccc1OCC(O)CN1CCN(c2ccccc2O)CC1 +Cc1c(Cl)cccc1NC(=O)C(C)S(=O)(=O)c1nccn1C +Cc1cc2c(SCC(=O)NCc3ccccc3C)ncnc2s1 +COC(=O)CN1C(=O)C(C)(C)Cc2ccc(N)cc21 +COC(CNC(=O)Nc1ccccc1F)c1ccsc1 +CCCNC(=O)Nc1sc(C(C)=O)c(C)c1C(=O)OCC +Cc1ccc(C)c(OCc2cc(C(=O)N3CCCC3C(N)=O)no2)c1 +Cc1cccc(NC(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +Cc1ccc(Cl)cc1NC(=O)CNc1cccc(C)c1C(N)=O +NS(=O)(=O)C1CCOCC1Cc1ccc(F)cc1 +CCCOC(=O)c1cc(-c2ccc(OC)cc2OC)nn1C +COCc1ccc(CNC(=O)c2ccc(F)cc2F)cc1 +Cc1ccc(CS(=O)(=O)c2ncnn2C)cc1 +O=C(CSc1ccncc1)NCc1cc(-c2ccccc2F)on1 +c1cc(CNc2ncnc3[nH]ncc23)c2c(c1)OCCCO2 +O=C(Nc1cccc2c1CCCN2)c1ccc(O)cc1 +Cc1cc(C)nc(C2CCN(C(=O)c3cscn3)C2)n1 +Cn1cc(NC(=O)Cc2c(Cl)cccc2Cl)cn1 +CCC(CO)NC(=O)NCc1ccc(CN2CCCC2=O)cc1 +COCCC1(CO)CCCN(c2cncc(C(=O)N3CCCC3)n2)C1 +O=C(c1ccc(S(=O)(=O)N2CCCCCC2)cc1)N1CCC1 +C=C(C)CN(CC)C(=O)Nc1ccc(-n2ncn(C)c2=O)cc1 +O=C(C1COCC2CN(Cc3nccs3)CC21)N1CCCC1 +O=C(CCCn1nnc2ccccc2c1=O)NCC1CCCO1 +COc1ccc(OC)c(C(C)NC(=O)C2CCCC2)c1 +CC(=O)c1ccccc1OCCSc1nnc(-c2ccoc2C)o1 +COc1ccccc1Cc1nn(CCO)c(=O)[nH]c1=O +O=C(CCOc1ccc(F)cc1F)NCC1COc2ccccc2O1 +Cc1c(C(=O)N2CCOCC2)cc(-c2ccccc2)n1C +O=C(CSc1nc(-c2ccccc2)ns1)Nc1nccs1 +CNC(=O)NCC(=O)NC(c1ccc(F)cc1)c1ccc(OC)cc1 +COc1ccc(NC(=O)c2ccc(Br)cc2)cc1OC +CC(=O)c1cc(C(=O)NCC2(c3ccccc3)CCC2)n(C)c1 +N#CCC(=O)Nc1nnc(SCc2ccccc2)s1 +CC(C)(C)OC(=O)N1CCC(CC(=O)Nc2cccc(C#N)c2)CC1 +CC(C)C(NC(=O)c1cccc(NC(N)=O)c1)c1ccccc1 +CN(Cc1cscn1)S(=O)(=O)c1ccc(O)cc1 +CCC(C)NC(=O)NCc1ccc(O)c(OC)c1 +CCC(C)N(C)C(=O)C(C)NC(=O)C1CCCC1 +CCSc1nc(CC(=O)N2Cc3ccccc3C(O)C2)cs1 +Cc1cc(NC(=O)Cn2cnc3ccccc32)[nH]n1 +O=C(Cc1cccs1)NCc1ccnc(OC2CCOCC2)c1 +CC(=O)c1[nH]c(C)c(C(=O)N2CCc3ccccc32)c1C +N#Cc1ccccc1NC(=O)CCOCC1CCCCO1 +CCOC(=O)NCCC(=O)Nc1ccc(C)cc1Cl +Cc1nc2c(cnn2C(C)C)cc1C(=O)N(C(C)C)C1CCOCC1 +CCOc1c(Cl)cccc1NC(=O)CCCc1nc(C)no1 +COc1ccc(CC(=O)Nc2cccnc2-n2cccn2)cc1 +CC(=O)Nc1cc2c(cc1N1CCC(C)CC1)n(C)c(=O)c(=O)n2C +O=C(C1CC(=O)N(c2cccc(Cl)c2)C1)N1CCCCC1 +COc1ccc(-n2cc(CNC(=O)NCc3ccccc3)nn2)cc1 +CCCCCNC(=O)C1CCCN(c2cnccn2)C1 +O=C(NCC(=O)N1CCCC1)Nc1ccc(-c2cc[nH]n2)cc1 +COc1ccc(C(=O)Nc2cn[nH]c2)cc1OC1CCCC1 +CC(NC(=O)Cn1ccc(=O)c2ccccc21)C1CCCCC1 +COC(=O)C(C)NC(=O)Nc1ccc(Oc2ccccc2)cc1 +NC(=O)C1CCN(C(=O)NCCOc2ccc3c(c2)CCC3)CC1 +CCN(CC)C(=O)CN(C)C(=O)c1cnc(-c2ccccc2)s1 +CC(NC(=O)c1ccc(Cl)c(Cl)c1)C(=O)N1CCCCC1 +CNC(=O)CN1CCN(S(=O)(=O)c2cc(C)sc2C)CC1 +O=C(C1CCCCC1)N1CCN(Cc2c(F)cccc2F)CC1 +Cc1noc(C)c1CC(=O)N1CCCc2cc(C(N)=O)ccc21 +CCOc1c(Br)cc(C)cc1C(N)=O +O=C(NCc1cc(Br)cs1)N1CCC(CO)CC1 +CCCC(CC)NC(=O)Nc1ccc(C(C)O)cc1 +CC(=O)N1CCCN(C(=O)Cc2ccc(OC(F)(F)F)cc2)CC1 +NS(=O)(=O)c1ccc2c(c1)CCN2Cc1cccc(F)c1 +O=c1[nH]ncc(NCCOc2ccc(C(F)(F)F)cc2)c1Cl +CS(=O)(=O)N1CCC(C(=O)N2CCOCC2)Oc2ccccc21 +COC(=O)c1cc2ccsc2n1CC(=O)NCc1cccc(F)c1 +Cc1ncc(CNC(=O)Nc2cccc(C(C)C)c2)s1 +N#Cc1cccc(OCCN2CCN(CC(F)F)CC2)c1 +CC(=O)N1CCN(C(=O)c2cc(Br)cn2C)CC1 +CC(C)(C)n1cc(C(=O)NCCCn2ccc3ccccc32)cn1 +C#CCN1CCN(C(=O)NCc2cccc(C(=O)NCCC)c2)CC1 +Cc1cccc(C(=O)N2CCCC2c2cnn(C)c2)n1 +CS(=O)(=O)c1ccccc1NC(=O)N1CCN(CC(F)F)CC1 +CN(Cc1ccc(F)cc1)Cc1nnnn1C1CC1 +Cc1cc(C)n(Cc2nc3c4cnn(C)c4ncn3n2)n1 +COCCNS(=O)(=O)c1ccc2c(c1)C(C)(C)CC(=O)N2C +CCOc1ccccc1OCC(=O)Nc1nc2ccccc2s1 +CCCCC1CCCC1NC(=O)c1ccncc1F +CCOc1ncccc1-c1cccc(-c2noc(C)n2)c1 +Cc1cc(C#N)ccc1OC(=O)c1cccnc1OCC(F)F +Cc1ccsc1C(=O)N1CCc2ncnc(-c3ccoc3)c2CC1 +CCCNC(=O)CSc1nc2ccccc2n(C)c1=O +N#Cc1cccc(CNCCc2n[nH]c(-c3ccco3)n2)c1 +NC(=O)C1CCN(C(=O)NCCc2coc(-c3ccc(F)cc3)n2)C1 +Cc1cccc(C(=O)N2CCN(C(C#N)c3ccccc3)CC2)n1 +CCn1cnc2c(-c3ccccc3)csc2c1=O +O=c1c(Cl)c(NCc2ccco2)cnn1Cc1ccccc1 +Brc1cc2c(c3c1CCNC3)OCO2 +Cc1nc(SCc2nnnn2-c2ccccc2)c(C#N)c(C)c1C +Cc1cc(C(=O)NCC2COCCO2)ccc1N +COC(=O)CCN1CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +CC(O)(c1cccc(OCc2ccccc2)c1)c1ccccn1 +Cc1cccc(C)c1NC(=O)Cn1cc(N)ccc1=O +CC(=O)N1CCC2(CC1)CN(C(=O)c1ccccn1)C2 +COc1cccc(N2CCN(C(=O)CC3CC4CCC3C4)CC2)c1 +O=C(Cc1c[nH]c2ccccc12)Nc1cccc(C(=O)NC2CC2)c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)NC1CCc2c(F)cccc21 +COc1ccc(Cl)c(NC(=O)N(C)C(C)c2ccccn2)c1 +Cc1ccc(OCC2CCCN(C(=O)OC(C)(C)C)C2)cn1 +CCOc1cc(NC(=O)N2CC(C)OC(C)C2)ccc1OC +Cc1cc(C(=O)COC(=O)c2cccc(O)c2)c(C)n1C1CC1 +Cc1nc(C(=O)N(C)CC(=O)NC2CC2)nn1-c1ccc(Cl)cc1 +Cn1nccc1CNc1cc(N2CCCC(CO)C2)ncn1 +CCOc1cccc2c1C(c1cncc(F)c1)NCC2 +CC(C)CN(CC(F)(F)F)C(=O)c1scnc1C1CC1 +C=C(C)CC1CCC(=O)N1CCc1ccc(OC)cc1 +CCOC(=O)c1csc(NC(=O)c2cc3c(s2)CCCC3)n1 +C=CCn1c(SCc2n[nH]c(=O)[nH]2)nnc1C1CC1 +COc1ccc(C(=O)CCC(=O)Nc2cn(C)c(=O)cc2C)cc1F +CC(C)c1nnnn1CC(=O)N1CCCC(COc2ccccc2)C1 +COC(=O)c1sc(NC(=O)c2cc(C)n[nH]2)nc1C1CC1 +CC(C)(C)OC(=O)Nc1ccc(N)cc1C(F)(F)F +COc1cccc2c(C)c(C(=O)Nc3ccc4c(c3)COC4)oc12 +CCCCCC(C)NC(=O)C1CC(=O)Nc2cc(F)ccc21 +Cc1cc(O)ccc1NC(=O)COc1ccccc1 +Cc1cccc(C(C)C)c1NC(=O)CN1CCOc2ccc(N)cc21 +Cc1cc2c(cc(C(=O)N3CCOCC3)n2CC2CCC2)s1 +CCOC(=O)c1c(C)n(CC(O)CO)c2ccc(O)cc12 +Cc1c(C(=O)N2CCc3cc(C(=O)N(C)C)ccc32)oc2ccccc12 +COCc1ccc(C(=O)Nc2cnn(-c3ccccc3F)c2)cc1 +CCCN(CCO)C(=O)NCc1ncc(C)c(OC)c1C +CNc1nnc(-c2cccn(C3CCCC3)c2=O)s1 +Cc1nn(C)c(C)c1CNc1cnn(Cc2ccccc2)c1 +COc1cccc(C(=O)NCCCNS(C)(=O)=O)c1F +COCCCNC(=O)Nc1cc(Br)ccc1C +CCCCN(C)C(=O)c1cc(-c2cccc(OC)c2)n[nH]1 +Cn1ccc(C(=O)NCc2ccc(OC(F)(F)F)cc2)cc1=O +Cc1nn(C)c(C)c1CNc1cnn(-c2ccccc2Cl)c1 +N#CCCN(C(=O)c1ccccc1F)c1ccccc1 +O=C(CSc1nnc(-c2ccco2)o1)c1cccs1 +Cc1cc(Cl)ccc1OC(C)C(=O)Nc1ccncc1 +CCOc1ccc(NC(=O)CCCn2cccc2)cc1 +CCN(Cc1cccc(C)c1)C(=O)c1cccc(S(C)(=O)=O)c1 +O=C(NCCc1nnc2n1CCCCC2)C1CC1c1ccc(F)cc1 +COc1cc(CNCCN2CCOCC2)cc(Br)c1O +O=C(Cn1cc(-c2nnco2)ccc1=O)Nc1ccc(F)c(Cl)c1 +CC(O)CC(C)CNC(=O)c1sccc1Br +CC(=O)Nc1ccc(S(N)(=O)=O)c2ccccc12 +COc1ccc(OC)c(NC(=O)c2ccccc2N)c1 +Cc1ccc(C)c(OCc2nnc3cc(C)c(N)cn23)c1 +CCC(C)N(C)C(=O)NCc1ccc(NC(=O)C(C)C)cc1 +O=C(NCc1cccc(Cl)c1)c1cc2cccnn2n1 +Cn1c(C2CC2)nc2cc(NC(=O)C3CCOC3)ccc21 +CCC(NC(=O)c1n[nH]c(N)n1)c1nc(C)c(C)s1 +Cn1c(C(=O)NCC(=O)NCC2CCCO2)cc2occc21 +CCc1ncc(C(=O)N2CCN(S(C)(=O)=O)CC2)cn1 +O=C(Nc1cccnc1)c1cc2cc(-c3ccccc3)ccn2n1 +Cc1ccccc1OCC(=O)NCc1ccnc(OC2CCC2)c1 +CC(C)Oc1ccccc1CNC(=O)c1ccc2c(n1)NCCS2 +C=CCN(CC=C)C(=O)c1cn(CC(=O)N(C)C)nn1 +CCOC(=O)CCC(C)NC(=O)c1c[nH]c2c(C)cc(F)cc2c1=O +CNC(=O)NCC(=O)NC(C#N)c1ccc(C(C)(C)C)cc1 +COc1cccc(C(=O)NCCc2nnc3n2CCCCC3)c1F +CNC(=O)C1CCCN1C(=O)NCC1CN2CCCCC2CO1 +Cc1cc(C)c(S(=O)(=O)Nc2cc(C(N)=O)ccc2C)c(C)c1 +CCNC(=O)CSc1nc2ccccc2n1CC(C)C +CCNC(=O)Cc1c(C)nc(SCc2ccc(F)cc2)[nH]c1=O +CNC(=O)c1cc(Cl)ccc1NCc1ccc(C#N)cc1 +CC(NC(=O)N1CCCC1c1nc2ccccc2s1)C1CCCO1 +Cc1ccccc1CC(C)(C)NC(=O)c1cc(C(N)=O)cs1 +COc1ccc(C2CC(=O)c3cn4ncnc4nc3C2)cc1OC +CCOC(=O)c1cc2cc(Br)ccc2oc1=O +CCN(CC)C(=O)C(C)Oc1cc(OC)ccc1C(C)=O +CCc1noc(CNc2ccc(C(=O)NC(C)CC)cc2C)n1 +Cc1noc(C2CN(C(=O)CCn3ccc(=O)[nH]c3=O)C2)n1 +O=C1CC(c2cc3ccccc3o2)c2cnn(Cc3cccnc3)c2N1 +CNC(=O)Nc1cc(NC(=O)Nc2ccccc2)ccc1C +COc1ccc(F)cc1CCC(C)(C#N)N(C)C +CCOc1ccc(NC(=O)c2cn(CC)c3ncccc23)cc1 +COc1ccc(NC(=O)NCc2noc3ccc(C)cc23)cc1 +Cc1cc(Cl)ccc1OCc1ncc(C#N)s1 +CCCCN(CCOC)C(=O)c1ccc2cc[nH]c2c1 +CCn1cc(Cl)c(C(=O)NCc2ccccn2)n1 +COC(=O)N1CCC(NC(=O)N2CCOC(c3ccccc3)C2)CC1 +Cc1n[nH]cc1NC(=O)c1ccc2[nH]c(=O)[nH]c2c1 +COCC(=O)Nc1cc(-c2cn3nc(OC)ccc3n2)ccc1Cl +COc1ccc(Cl)cc1CC(=O)N1CCCC1Cn1cc(C)cn1 +CCCNC(=O)N1CCc2c(c(C(=O)Nc3ccccc3)nn2C)C1 +CCN(CC)c1nc2cc3c(cc2cc1CC#N)OCCO3 +COc1cc(CCC(=O)NC(C)Cn2c(=O)oc3ccccc32)on1 +Cc1ccc(S(=O)(=O)NCc2cccs2)cc1C +COCCCN1CC2(CCCCN2C(=O)Cc2ccccc2)CC1=O +CCOCCS(=O)(=O)N1CCC(O)(C(F)(F)F)CC1 +Cc1ccc(C)c(NC(=O)CSc2nc(O)nnc2C)c1 +COC(=O)c1ncccc1OCc1ncc(-c2ccccc2)s1 +CC(c1cccnc1)N1CCN(C(=O)Cc2ccc(F)cc2F)CC1 +Cc1nscc1C(=O)OCCC1CCCCO1 +COC(=O)c1cnn(-c2cccc(Br)c2)c1N +CC(=O)N(CCCC(O)c1ccc(F)cc1)C(C)C +COCC(=O)N1CCN(CC(=O)NCC2CCCCC2)CC1 +O=S(=O)(Cc1ccc(Cl)cc1)NCC(O)c1ccsc1 +COC(=O)c1ccc2cc(N3CCCCC3)ccc2n1 +COc1ccc(NC(=O)c2nc(C)oc2C)cc1F +Cc1cc(NC(=O)c2ccc(-n3cncn3)cc2)no1 +CN(C)S(=O)(=O)N1CCC(C(=O)Nc2cccnc2)CC1 +CCc1ccc(S(=O)(=O)N2CCNCC2)cc1 +CN(C)S(=O)(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +CCCn1ncnc1C(C)NC(=O)c1cnn(CCC)c1C +CCOc1cc(N)cnc1NCc1ccc(Cl)cc1 +CCc1nc(CC(=O)N(C)C(C)c2ccc(C)cc2)cs1 +COc1cc(OC)cc(C(=O)Nc2ccc(OC)nc2)c1 +CCc1cccc(CC)c1NC(=O)C(N)c1ccccc1 +CC(=O)Nc1cccc(NC(=O)c2c[nH]c3cccc(F)c23)c1C +CCCNC(=O)c1ccc(NC(=O)c2ccc(=O)[nH]c2)cc1Cl +O=S(=O)(NCC1CCOC1)c1c(Cl)cc(Cl)cc1Cl +COc1ccc(OCCN(C)C(=O)Nc2cnccc2C)cc1 +CCC(=O)N1CCc2ccc(NC(=O)c3cccs3)cc2C1 +CCN1CC2(CCN(C(=O)c3ccc4[nH]nnc4c3)CC2)CC1=O +CCc1n[nH]c(C2CN(Cc3noc(C4CC4)n3)CCO2)n1 +Cc1ccc(S(=O)(=O)N(C)c2ccc(N)c(C)c2)s1 +CC=CCOC(=O)CC(C)NC(=O)c1ccccc1 +Clc1ccc(OCCCN2CCOC(Cn3cncn3)C2)cc1 +CNc1ccc(Cl)c(C(=O)Nc2ccc(Br)cn2)n1 +CC(Oc1ccc(C#N)cc1)C(=O)NCC1CN2CCCCC2CO1 +CCCNc1nnc(-c2cc(C)oc2COC)s1 +Cc1cccc(C(=O)N2CCC3C2CC(=O)N3c2ccsc2)n1 +CC(C)c1ccc(OCC(=O)Nc2ccc(S(C)(=O)=O)cc2)cc1 +CS(=O)(=O)c1cccc(OS(=O)(=O)c2ccc(F)cc2)c1 +O=C(Nc1cnn(Cc2ccc(Cl)cc2)c1)NC1CCC(O)CC1 +Cc1ccc2cccc(C(=O)N(C)Cc3cccc(C#N)c3)c2n1 +O=C(CCc1ccc(-c2ccccc2F)o1)NCC1CCCO1 +Cc1cc(NC(=O)NC(CO)CC(C)C)ccc1F +COC(=O)C(C)NC(=O)Cc1n[nH]c(=O)c2ccccc12 +COCCNC(=O)c1cccc(C2CCCN(C(=O)NC(C)C)C2)c1 +CCc1ccccc1NC(=O)CSc1nc(C)cs1 +Cc1noc(CCCC(=O)Nc2ccc(Cl)cc2O)n1 +O=C(CN1CCCCCC1=O)NCc1ccccc1 +CCSc1ccccc1C(=O)N1CCOC(C)C1 +Cc1cc(C(=O)Nc2ccc(C(N)=O)c(N3CCCCC3)c2)nn1C +Cc1ccc(C)c(OC(C)(C)C(=O)N2CCNCC2)c1C +C=CCCOC(C)C(=O)NC(C)c1ccc(C#N)cc1 +O=c1oc2cc(CO)ccc2n1CCCOc1ccccc1 +COC(=O)c1ccc(C(=O)Nc2ccccc2C#N)cc1 +O=C(NCCCNC(=O)c1cc2ccccc2o1)c1ccco1 +COc1cccc(NC(=O)CCn2ccc(C)n2)c1 +CN(CC(N)=O)C(=O)c1ccc(-c2ccc(Cl)cc2)o1 +Cc1nccn1-c1ccc(NC(=O)Nc2ccc(F)c(Cl)c2)cc1 +COc1ccccc1CC(=O)N1CCCC(CNC(=O)C(C)C)C1 +COc1cccc(CCC(=O)Nc2cccc(S(N)(=O)=O)c2)c1 +COc1cccc(OCc2nc(C#N)c(N3CC(C)OC(C)C3)o2)c1 +CCCc1cc(N2CCN(C(=O)C3CCC3)CC2)nc2nnc(C)n12 +O=C(Nc1cccc2cnccc12)N1CCCCCC1 +Cc1c(CNC2CCOC2c2ccc(F)c(F)c2)cnn1C +O=C(NCc1ccc2nonc2c1)C(c1ccccc1)n1cnnn1 +CCOc1cccc(C(=O)Nc2sc3c(c2C(=O)OC)CCC3)c1 +Cc1nc2c(C)cccn2c(=O)c1NC(=O)c1ccc(F)cc1F +CCC(=O)Nc1ccc2nc(SCC(=O)NC3CC3)sc2c1 +N#Cc1ccc(C=CCN2CCOC(c3nccs3)C2)cc1 +O=S(=O)(c1cc(F)ccc1F)N(Cc1ccsc1)C1CC1 +O=C(CCOc1ccccc1)NCCc1ccccc1 +CC(C)c1cc(N)cc2c1OC(c1ccccc1)C(=O)N2 +Cc1ccc(C(=O)Nc2cccc(N3CCOC3=O)c2)cc1F +COc1cccc(S(=O)(=O)Cc2cc(C)nc3ccccc23)c1 +CC1(C)CN(Cc2cnc(C3CC3)s2)CCO1 +Cc1c(C(N)=O)sc(NC(=O)c2ccccc2)c1C(=O)OC(C)C +COc1ccc(C(=O)Nc2ccc3c(c2)COC3)cc1 +Cc1cc(NS(=O)(=O)c2c(C)cccc2N)n(C)n1 +Cc1cccc(C(=O)Nc2ccc(-c3ncc[nH]3)cc2)n1 +Cc1nc(NC(=O)c2cn(C)c3c(F)cccc3c2=O)sc1C +CC(=O)Nc1nc(C(=O)N(Cc2cccnc2)C2CC2)cs1 +CC1CC(C)CN(S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)C1 +CCCC(=O)N1CCCCC1C(=O)N(CC)Cc1cccs1 +O=C(Nc1nnc(C2CC(=O)N(c3ccccc3)C2)o1)c1ccncc1 +NC(=O)C1CCCN(C(=O)CNc2cc(F)c(F)c(F)c2)C1 +CCS(=O)(=O)NCCNC(=O)c1cc(-c2ccc(C)cc2)no1 +CCc1ccc(C(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)cc1 +CCOC(=O)c1c(NC(=O)Cc2ccccc2)sc(C)c1C +NC(=O)c1ccsc1NC(=O)c1ccccc1Br +CCCNC(=O)CNC(=O)NCc1cccc(Cl)c1 +O=S(=O)(Cc1ccccc1)N(CCO)Cc1ccsc1 +COc1ccc(OC)c(CN(C)C(=O)c2scnc2C2CC2)c1 +Cc1ccc2ncc(C(=O)NCc3nc4ccccc4s3)n2c1 +CCCC(NC(=O)c1cccs1)c1nnc2ccccn12 +CCc1nc(-c2cnccn2)sc1-c1csc(NC)n1 +CCCC1=C(C(=O)OC)C(c2cccnc2)NC(=O)N1CC +CCOc1ccccc1C(=O)Nc1ccccc1O +OC1CCN(c2ccnc(N3CCCC(c4ccn[nH]4)C3)n2)CC1 +NC(=O)C(OC(=O)CCc1ccsc1)c1ccc(F)cc1 +CCCOC(=O)c1cc(-c2ccc(C)cc2)nn1C +CCCCCNC(=O)C1CC(=O)N(Cc2ccc(C)cc2)C1 +O=S(=O)(c1ccc(F)cc1Br)N1CCCC(O)C1 +Cc1ccc(CNC(=O)c2cccc(Nc3ncccn3)c2)n1C +COc1ccc(C(=O)Nc2nc(C)c(SC)s2)cc1OC +CCOCCn1cnc2sc(-c3ccccc3)c(C)c2c1=O +O=C(COc1ccccc1O)N1CCN(c2ccccc2)CC1 +CCOC(=O)c1cc2ncc(C(F)(F)F)cc2s1 +CN(C(=O)c1cc2ccccc2oc1=O)c1ccccc1 +CC(=O)Nc1cc(NC(=O)NCc2ccc(C)cc2)ccc1F +CCC(C)C(NC(N)=O)C(=O)N1CCC(C(=O)c2ccccc2)CC1 +COc1ccc(CNC(=O)Nc2ccc(OC)c(F)c2)cc1F +CCCNC(=O)NC(C)(C)C(=O)Nc1ccc2[nH]c(C)cc2c1 +CNC(=O)C(C)NC(=O)c1ccc(C(N)=O)nc1 +CS(=O)(=O)c1ccccc1NC(=O)NC1CCCc2ccccc21 +NC(=O)C1CCN(C(=O)CCC(=O)NCc2ccccn2)CC1 +C#CCNC(=O)C1CCCN(S(=O)(=O)c2c(C)n[nH]c2C)C1 +N#CC1(C(=O)Oc2ccc3ccc(=O)oc3c2)CCCC1 +CC(NC(N)=O)C(=O)NC(C)c1cccc(OC(F)F)c1 +CCNC(=O)N1CCN(C(=O)CCNC(=O)C2CCCCC2)CC1 +Cc1cc2c(=O)n(CC(O)CN3CCOCC3)cnc2s1 +Cc1ccc(C(=O)Nc2cc(-n3cnnn3)ccc2C)s1 +CCOC(=O)c1cc(S(=O)(=O)N2CCCCC2C)cn1C +CC(C)C(=O)NCCNS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CSc1ccc(N2CCN(CC(=O)N3CCOCC3)CC2)nn1 +COC(=O)C1CCCCN1C(=O)c1csc(-c2ccc(F)cc2)n1 +Clc1cccc(NCc2nc(-c3ccco3)no2)c1-n1cccn1 +CC(C)(C#N)NC(=O)C1CCN(c2nc3ccccc3o2)CC1 +COc1ccc2cc3c(nc2c1)N(C(=O)COc1ccccc1)CC3 +O=C(Cn1nnc(-c2ccc(Cl)cc2)n1)N1CCCC1 +CC(NC(=O)c1ccc(Cl)cc1)c1ccccc1N +CSc1ccc(C(=O)OCC(=O)c2[nH]c(C)c(C(C)=O)c2C)cc1 +Fc1ccc2c(c1)CCN(Cc1nccn1C(F)F)C2 +CCSc1ccc(NC(=O)Cc2cccc(F)c2)cn1 +O=C1CN(C(=O)c2sccc2S(=O)(=O)NC2CC2)CCN1 +CC(O)CNC(=O)COc1cccc(C(C)C)c1 +Cc1ccc(C(N)=O)c(OCc2cc(=O)n(C)c(=O)n2C)c1 +CNC(=O)c1cn[nH]c1C1(C)CCN(C(=O)C2CCOCC2)CC1 +CSc1cccc(NC(=O)NCc2ccccn2)c1 +COC(=O)c1ccc(NCc2ccc(F)cc2)nn1 +CC(C)NC(=O)c1ccc(Br)cc1O +COc1ccc(-c2nnc(-c3nnn(-c4ccccc4)c3C)o2)cc1 +CCOc1ccc(C(=O)NCC(=O)NCc2ccco2)cc1 +CC(C)(C)n1nc(-c2cccc(C(F)(F)F)c2)c(C#N)c1N +O=C(CCSc1nnnn1C1CCOCC1)c1ccc(F)cc1 +COC(=O)C1CCN(C(=O)CCCc2ccccc2)CC1 +CCCC(CCC)C(=O)N1CCN(S(=O)(=O)C2CC2)CC1 +CCc1ccccc1NC(=O)c1cnc(C2CC2)nc1N +CN(Cc1cccc(O)c1)C(=O)c1cccc(N)c1 +Cn1cc(C(=O)Nc2ncn(Cc3ccccc3)n2)ccc1=O +COc1ccc(C(C)Nc2cnn(C)c2)cc1OC +COc1ncccc1C1NCCc2c(C)ccc(Cl)c21 +CC1=C(C(=O)N2CCOC(CCc3ccccc3)C2)OCCO1 +CCC1CCC(NC(=O)NCC(O)c2ccc(OC)cc2)CC1 +CCCCn1nnnc1NCc1cccc2ccccc12 +Cn1c(C(=O)Nc2cccc(F)c2)nnc1-c1ccccn1 +O=c1[nH]c(Cc2cccnc2)nc2sc3c(c12)CCCC3 +c1ccc(-n2cc(Nc3ccc4nnnn4n3)cn2)nc1 +COCCN(Cc1cccs1)C(=O)NC(C)c1ccccn1 +Cc1cc(NC(=O)CCC(=O)c2ccc3c(c2)OCCO3)n(C)n1 +CC(CNC(=O)N(C)Cc1ccc(C#N)cc1)Cn1cccn1 +CCOC(=O)CN(CC)C(=O)c1csc2c1CCCC2 +CCOC(=O)CNc1cnc2sccn2c1=O +CC(C)c1ncc(Cl)c(C(=O)Nc2ccc(F)cc2)n1 +Nc1ccc(C(=O)Nc2nc3ccc(Br)cc3s2)cc1 +COc1ncccc1CNC(=O)NCc1cnn(-c2ccccc2)c1 +COc1ccc2c(c1)C1(CC1)CNC2c1ccco1 +CN(Cc1nc2ccccc2s1)C(=O)c1cn[nH]n1 +COc1ccc(C(O)CNc2ccc(F)cc2)cc1N +O=C(NCc1ncc[nH]1)C1CCC(=O)N(CCc2cccc(F)c2)C1 +CNC(=O)C(CC(C)C)NC(=O)c1ccc2c(c1)COC2 +Cc1noc2ncc(C(=O)N(CCO)Cc3ccccc3)cc12 +CC1CC1C(=O)NCCc1c[nH]c2cccc(C3(O)CCOCC3)c12 +CCCCc1noc(CNc2cc3c(cc2Cl)NC(=O)CO3)n1 +N#CC(Cc1ccc(O)cc1)C(=O)NCc1ccccc1 +COC(CNC(=O)c1ccsc1)c1ccccc1 +CC(Sc1nc2ccccc2o1)C(=O)NCc1ccc(F)cc1 +O=C(Nc1ccc2c(c1)OCCO2)Nc1ccc(Cl)cc1F +CCC(C)c1cc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)on1 +Cc1ccc(N)c(-c2nc3cccnc3n2C(C)C)c1 +O=C(CN1CCCCC1=O)Nc1ccccc1N1CCOCC1 +Cn1c(CCNC(=O)c2ccc(OC(F)F)cc2)nc2ccccc21 +CCOC(=O)C1CCN(C(=O)Cc2ccc3c(c2)OCCO3)CC1 +Cc1noc(C)c1C(C#N)CC(=O)N1CCCCCC1 +Cc1occc(=O)c1OCc1noc(C(=O)NCc2ccco2)n1 +COCC(C)NC(=O)CSc1nc(C)cc(C)c1C#N +O=C(NCc1ccc(OC2CCCCC2)nc1)C1CCCO1 +CN(C)S(=O)(=O)c1cc(C(=O)NCc2csc(=O)[nH]2)co1 +CCC(=O)Nc1ccc(-c2nnc(SCC(=O)N(C)C)n2C)cc1 +N#CCCN(C(=O)CC1CCCC1)c1ccc2c(c1)OCCO2 +COc1cccc(-c2cccc(CN3CCOCC3)c2)n1 +O=C(CC1CCCCC1)Nc1ccccc1C(=O)NC1CC1 +Cc1ccccc1-n1nnc(-c2ccncc2)c1N +CCn1ncc(NC(=O)Cn2ccc(-c3ccc(C)cc3)n2)n1 +CC(C)C(=O)Nc1ccc(CNC(=O)c2cc(C(N)=O)cs2)cc1 +CCN(CC)c1ccc(C(=O)N2CCC(n3cccc3)CC2)c(O)c1 +COc1ccccc1NC(=O)CSc1nc(C)c(C)c(C)c1C#N +O=C(Nc1ccc(F)cc1)Nc1ccc2c(c1)C(=O)OC2 +CCN(CC)C(=O)CCC(=O)N1CCCC(C(=O)N(C)C)C1 +COc1ccc(NC(=O)c2cnn(-c3ccccc3)c2)cc1Cl +Fc1cc2c(cc1F)C(c1ccc3ncccc3c1)NCC2 +COCC(O)CN1CCOC(c2ccc(C)cc2C)C1 +Cc1ccc(OCc2coc(-c3cccs3)n2)nc1 +CCS(=O)(=O)N1CCC(C(=O)N2CCCCC2C)CC1 +Cc1cc(OCC(N)=O)c(C)cc1CN1CCOCC1 +Cc1nc2ccccc2c(=O)n1-c1ccc(NC(=O)C2CC2)cc1 +COCC(C)N1CCN(C(=O)c2cccc(OC)c2OC)CC1 +CCN(Cc1ccccc1Cl)C(=O)Nc1cnccc1C +Cc1nc2n(n1)CC(NC(=O)c1cn(C)nc1C(C)(C)C)CC2 +O=C(CSc1nnc(-c2ccco2)o1)c1c[nH]c2ccccc12 +Cc1cnccc1C1NCCc2cccc(Cl)c21 +C=CCNc1ncnc(NCCc2cccs2)c1N +COc1ccc(C(=O)N2CC(C)C2c2ccccc2)cc1-n1cnnn1 +Cc1ccc(Cl)cc1NC(=O)c1cc2cccnc2n(C)c1=O +Cc1cc(C)n(Cc2ccc(Br)cc2)n1 +O=C(NC1CC1)c1ccc(S(=O)(=O)NCc2ccco2)cc1 +CCOc1ccc(C(=O)CSc2cc(C#N)ccn2)cc1 +O=C(NCc1ccc(O)cc1)c1ccc2c(c1)OCCCO2 +Cc1ccc(C)c(N(C)Cc2nnnn2C2CC2)c1 +O=C(NCCCC(=O)N1CCCC1)c1n[nH]c2c(Cl)cccc12 +COC(=O)c1cc(NCc2ccc(F)cc2)c(F)cc1F +CCOc1ncccc1C(=O)N1CC(Oc2ccccc2CC)C1 +CC1CN(C(=O)CSc2ncccc2C#N)CC(C)O1 +Cc1ccc(C)c(CC(=O)Nc2ncnc3c2CCC3)c1 +COc1ccc(NC(=O)CNC(C)=O)cc1OCC(F)(F)F +CNC(=O)NCC(=O)NC(C)Cc1ccc(C)cc1C +CNC(=O)C1CCCCN1Cc1nc2sc(C)c(C)c2c(=O)[nH]1 +CCOCc1ccc(NC(=O)NCc2ncc[nH]2)cc1 +CC(C)Oc1cccc(CC(=O)OCC(N)=O)c1 +Cc1cc(C(=O)NCCc2ccc(OC(F)F)cc2)on1 +Cn1cnc2c1c(=O)n(CC(=O)Oc1ccccc1F)c(=O)n2C +O=C(Nc1ccccc1C(F)(F)F)c1cccnc1 +Cc1ccc(C(C)NC(=O)C(C)NS(C)(=O)=O)o1 +CCC(C(=O)NCc1nccc(N2CCCCC2)n1)c1ccccc1 +COc1cc(S(=O)(=O)N2CCCCCC2)c(OC)cc1C +COC(=O)c1sc(NC(=O)OC(C)(C)C)nc1C +NC(=O)C1CCN(C(=O)c2cc(=O)[nH]c3ccccc23)CC1 +COc1ccc(C(NC(=O)Cc2ccsc2)C2CC2)cc1 +CCN(C)S(=O)(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +Cc1nnc(SCCCNC(=O)Nc2ncccn2)s1 +Cc1c(C#N)c(N)n(-c2cccc(C(F)(F)F)c2)c1C +CC(NC(=O)CNC(=O)C1CC1)C(=O)NC(C)(C)C +CC(=O)NC(C(=O)NC(C)C1CCCO1)C(C)C +O=C1c2ccccc2S(=O)(=O)N1CC(O)c1ccc(Cl)cc1 +CCOC(=O)c1csc(NC(=O)C2CC2C)n1 +CCc1nc(CCNC(=O)Nc2cccc(C(=O)NC)c2)sc1C +CCC(C)n1cnc(S(=O)(=O)N(C)c2ccc3ccccc3n2)c1 +O=C1CNC(=O)C(c2ccc(Br)cc2)N1 +COC(=O)CN(C(=O)C1COc2ccccc2C1)C(C)C +O=S(=O)(Nc1cnc(-c2ccccc2)nc1)c1ccc(F)cc1F +Cc1ccc(SCC(=O)Nc2nnc(C(C)C)o2)cc1C +N#Cc1c[nH]c2ccc(OC(F)(F)F)cc2c1=O +O=S(=O)(NCCCN1CCOCC1)c1ccc2c(c1)CCO2 +COc1ccc(F)c(NC(=O)c2cscc2C)c1 +O=C(NCCn1nnn(-c2cccs2)c1=O)c1cnccn1 +CN(Cc1ccccc1OC(F)(F)F)C(=O)CN1CCOCC1 +Nc1nc(C(=O)N2CCc3ccc(O)cc3C2)n[nH]1 +CC(C)(C#N)C(=O)Nc1ccc(Cl)cc1Cl +CCn1cc(C(=O)Nc2ccnc3ccnn23)cn1 +Cc1cc(C)c(S(=O)(=O)Nc2cccc(CO)c2)c(C)c1 +CSc1cccc(NC(=O)c2ccccc2NC(=O)NC(C)C)c1 +N#CC(C(=O)C1CC=CC1)c1nc(N)nc(Nc2ccccc2)n1 +CNC(=O)C(C)CN(C)C(=O)Nc1cnn(-c2ccccc2Cl)c1 +Cc1cn2c(CN3CCC(Oc4ccccc4)CC3)c(C)nc2s1 +O=C(CCNc1ncccn1)Nc1nncs1 +CCS(=O)(=O)N1CCCC(C(=O)Nc2ccc(C)c(C)c2)C1 +CC(C)(C)CC(=O)NCC(=O)N1CCCC1c1ccncc1 +CC(C)c1nnc2n1CCN(C(=O)c1cc(-c3cccnc3)on1)C2 +CCOC(=O)C(NC(C)=O)(Nc1ccc(Cl)cc1)C(F)(F)F +COc1ccc(Cl)cc1CC(=O)Oc1ccc(NC(C)=O)cc1 +COCc1cc(NCCN2CCNC2=O)ncn1 +C#CCNC(=O)c1oc2ccc(OCC)cc2c1C +CCNC(=O)N1CCN(CCOc2ccc(OCC)cc2)CC1 +O=C(CCn1cncn1)N1CCC(CN2CCOCC2)CC1 +CCCCn1nc2ccc(S(=O)(=O)N3CCCC3)cn2c1=O +CC1CC(C)CN(C(=O)c2cc(NC(=O)c3cccs3)n(C)n2)C1 +CN(C)S(=O)(=O)c1ccc(C(=O)NCCCC2CCCC2)cc1 +Cn1c(=O)c2ccc(C(=O)N3CCCC(O)C3)nc2n(C)c1=O +Cc1ccc(N2CC3(CCN(C(=O)c4ccoc4)C3)CC2=O)s1 +CNC(=O)c1cc(OC)ccc1NC(=O)c1scnc1C1CC1 +Cc1noc(C)c1C(=O)NCC1(N2CCOCC2)CCCCC1 +Cc1nc(-c2c[nH]c(C(=O)N3CC(C)OC(C)C3)c2)cs1 +CN(C(=O)c1ccccn1)c1nc2c(s1)CCc1c-2cnn1C +COC(=O)NCC(=O)Nc1ccc(F)c(C(N)=O)c1 +CC1CCN(C(=O)N2CCN(c3ccc(F)cc3)CC2)CC1 +COc1cc(CNC(=O)c2cccc(OC)c2O)ccn1 +CCCCc1noc(C(C)OC(=O)c2cccnc2)n1 +Cc1ccc(C(=O)Nc2cccc(-c3nnnn3C)c2)s1 +O=S(=O)(NCCc1ccsc1)c1ccc(O)cc1 +CCCNc1ccc(C(=O)NCC(C)(C)C)nn1 +CN(Cc1cnn(C)c1)C(=O)C1CC(=O)N(Cc2ccco2)C1 +COc1cc(OC)cc(C(C#N)N2CCCCC2)c1 +CCCc1cc(C(=O)Nc2cccc(C(=O)N3CCOCC3)c2)[nH]n1 +O=C(NCCC1CCCCC1)NCC1CN2CCCCC2CO1 +Cc1c(C(C)NC(=O)CN(C)S(C)(=O)=O)cnn1C +Cc1occc1C(=O)Nc1cccc(N2CCOC2=O)c1 +COCc1cccc(CNC(=O)CSc2nc(C)cc(N)n2)c1 +CC(Cn1ccnc1)NS(=O)(=O)c1cc(N)cs1 +Nc1ncnc(Nc2ccc(Cl)cc2Cl)c1N +CNC(=O)c1ccc(CN(C(=O)c2ccc(=O)[nH]c2)C2CC2)cc1 +CN(C)C(=O)c1ccc(CN2CCCC(c3nccs3)C2)[nH]1 +O=C(OCc1cc(-c2ccc(Cl)cc2)on1)c1ccc(=O)oc1 +COc1cc(OC)c2c(c1)C(C#N)N(C(C)=O)C=C2 +Nc1ccc(C(=O)Nc2cccc3ccccc23)nn1 +CN(CCC(O)c1ccccc1)C(=O)c1cnc(N2CCCC2)nc1 +CC(C)Cn1ncc2cc(C(=O)N(C(C)C)C(C)C)cnc21 +Cc1ccc2nc(NCc3cncnc3)sc2c1 +CCOC(=O)c1[nH]c(-c2cccs2)nc1NC(=O)c1ccco1 +O=C(c1ccc(C(F)(F)F)cc1)N1CCN(c2ccccc2)CC1 +COCC(C)NC(=O)Nc1cccc(Cl)c1F +CC1CNc2cc(S(=O)(=O)N3CCNCC3)ccc2O1 +CC(=O)Nc1cccc(CNC(=O)N(C)C(C)C)c1 +CC1CN(Cc2cccc(CNc3ccc4nnnn4n3)c2)CCO1 +CN(CCC#N)C(=O)CSc1ccc(N)nc1 +O=C(Nc1cccc(F)c1)NC1CC(=O)N(Cc2ccc(F)cc2)C1 +Cc1ccc(C(C)C)c(OCC(=O)NC(C)CO)c1 +COC(=O)Cn1cnc2sc(C)c(-c3ccc(C)c(C)c3)c2c1=O +Cc1cc(NC(=O)NCC2COc3ccccc3O2)n(C)n1 +Cc1ccc(NC(=O)C(NC(=O)c2ccco2)C(C)C)c(Cl)c1 +CN(Cc1cccc(C#N)c1)C(=O)Cc1ccc[nH]1 +CCC(C(=O)NCCOc1cccnc1)c1c(C)noc1C +CC(CNC(=O)c1sccc1Cl)Oc1cccnc1 +CC(C)n1c(=O)c2ccccc2n(Cc2cccc(F)c2)c1=O +c1ccc(CSc2ccc(-c3cccs3)nn2)nc1 +CC(C)CNC(=O)c1nc2c(F)cccc2s1 +CN(Cc1nc(-c2cccnc2)no1)C(=O)Cc1cccc(F)c1F +CCCn1cc(Br)cc1C(=O)N(CC)CCC#N +CC1=C(C(=O)Nc2nnc(C(F)F)s2)C(=O)OC1(C)C +Cc1ccccc1CNc1cc(C(N)=O)ccc1C +CCC(C)NC(=O)c1sc(NC(=O)Nc2ccccc2)nc1C +COC(=O)N1CCC2(O)CCCCC2C1c1cc(OC)ccc1OC +COc1ccc(C(=O)NC2Cc3ccccc3NC2=O)cc1 +Cc1c(C(=O)Nc2cnn(-c3ccccc3Cl)c2)cnn1C +CC(C)n1c(=O)oc(=O)c2cnc(-c3ccccc3)nc21 +CC(Cn1cccn1)NC(=O)c1ccc(C(F)(F)F)nc1 +CNC(=O)CN(C)C(=O)Cc1coc2ccc3ccccc3c12 +CC1Oc2ccc(NC(=O)c3cccc(C(N)=O)c3)cc2NC1=O +CC1CN(S(=O)(=O)Nc2ccc(CC#N)cc2)CC(C)O1 +CC1(C)C2CCC1(C)C(NC(=O)CSc1nnc3ccccn13)C2 +Clc1ccc(OCc2cn(Cc3cccnc3)nn2)c(Cl)c1 +N#Cc1ncn(CC(=O)N(C2CCCC2)C2CC2)c1C#N +CNC(=O)COC(=O)C(C)Oc1cccc(Cl)c1 +CC(C)(CNC(=O)Nc1ccccn1)c1ccc2c(c1)OCO2 +CC(Cc1ccc(Cl)cc1)N(C)C(=O)c1ccon1 +COc1ccc(F)c(NC(=O)COCc2nc(C)no2)c1 +CCOC(=O)c1c(C)nc(C(F)(F)F)nc1C(F)(F)F +O=C(C1CC1)N1CCC(Oc2nc3ccc(F)cc3s2)CC1 +O=C(CCNc1ncccn1)N1CCN(c2nccs2)CC1 +CC(CCOc1ccccc1)C(=O)N1CCCC(N2CCCC2=O)C1 +CN(CCC#N)C(=O)c1noc2c1COc1ccccc1-2 +COc1ccc(N)c(C(=O)NC(C)CCC(C)C)c1 +CC1COCC(C)N1C(=O)C1(C)Cc2ccccc2C(=O)O1 +COc1cccc(Nc2nnc(SCc3nccn3C)s2)c1 +CC(C)(NCC(=O)NCC1CC1)c1ccc2c(c1)OCCO2 +C=CCn1c(SC2CCN(C(C)C)C2=O)n[nH]c1=O +COc1ccnc(NC(=O)CNC(=O)c2cc(C)cc(C)c2)c1 +CCC1CCCN(C(=O)C(C)NC(=O)c2cccs2)C1 +Cc1cc(C)c(C(=O)NCCCCn2ccccc2=O)c(C)c1 +CCOC(=O)C1CCCN1C(=O)Cn1cnc(N)n1 +Nc1ccc2c(n1)N(CCCc1ccccc1)C(=O)CO2 +O=C(NC1(c2ccc(F)cc2F)CCOCC1)c1ccco1 +CC(C)(C)c1nnc(SCCC(=O)Nc2cccc(C#N)c2)n1N +CC(=O)N1CCN(CCC(=O)c2ccc(F)cc2)C(C)(C)C1 +O=C(NCCCn1ccnn1)C1CCC(=O)N(C2CCCC2)C1 +CC1C(=O)NCCN1C(=O)c1ccc(-c2ccccc2)cc1 +O=C(c1ccc2[nH]nnc2c1)N1CCCC(OCc2ccccn2)C1 +Cn1c(=O)[nH]c2cc(C(=O)OCCCOC3CCCC3)ccc21 +O=S(=O)(N1CCCC1)N1CCCN(Cc2nccs2)CC1 +CSc1c(CCC(C)O)c(O)c(C)c(O)c1C(C)=O +CC(=O)c1ccc(C(=O)N2CCCC(C(F)(F)F)C2)cc1 +COc1cc(CNC(=O)c2ccc3c(c2)nnn3C)c2ccccc2n1 +COCCS(=O)(=O)N1CCCCCC1c1ccco1 +CC1CCC(NC(=O)CCC(=O)N2CC(C)Oc3ccccc32)CC1 +Cc1cccc(Oc2nc(C)nc(N3CCCC3)c2N)c1 +COC(C)c1nc(CN(C)c2nnc(C(F)(F)F)s2)cs1 +CCOc1ccccc1NC(=O)CCNC(=O)c1ccccc1 +C#CCNC(=O)CSc1nc2cc(Cl)ccc2c(=O)n1CC=C +CC(C)C(=O)Nc1ccc(CNC(=O)c2cc3ccccc3[nH]2)cc1 +CCCN(C)S(=O)(=O)c1c(NC)nc2ccccn12 +Cc1ccc(CNc2nccn(-c3cccc(C)c3)c2=O)cc1 +CCCC(=O)N1CCC(c2nn(C)c(=O)n2C2CC2)CC1 +CCOC(=O)C(O)Cc1ccc(Cl)c(C)c1F +O=S1(=O)N=CN(Cc2ccc(Cl)cc2)c2ccccc21 +Cc1ccc(C(=O)Nc2cnc3c(C)cccn3c2=O)cc1 +Cn1cccc1-c1csc(NC(=O)c2cc3c(s2)CCC3)n1 +COC(=O)c1c(C)[nH]c(C(=O)OCC(=O)Nc2ccccc2F)c1C +COc1cccc(Cc2nc3ccccn3c2C(C)O)c1 +COCc1ccccc1CNC(=O)CSc1ccccn1 +O=C(c1ccc(F)c(S(=O)(=O)N2CCOCC2)c1)C1CC1 +Cc1nc(CN(C)C(=O)NCc2ccc3c(c2)OCO3)no1 +COc1ccccc1CN(C)C(=O)COc1ccc(C(C)=O)cc1 +Cn1c(=O)c2cc(Br)ccc2n(C)c1=O +O=C(Nc1ccccc1OC(F)(F)F)c1cc[nH]n1 +O=C(NCc1ccco1)C1CCCN1C(=O)CN1CCCCC1=O +Cc1cccc(C)c1-c1c(-c2ccccc2)ncn1CC(O)CO +CC(C)(C)NC(=O)CNC(=O)c1cc(F)ccc1F +CC(NC(=O)c1cc(Cl)c[nH]1)c1cccc(N2CCCC2)c1 +O=C1OCCC1Sc1nnc(-c2ccccc2F)n1C1CC1 +Cn1nc(CNC(=O)C2CC=CCC2)c2c1CCCC2 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cn(C)nc1C(F)(F)F +CC(=O)N(C)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +OCc1nnn(-c2nccs2)c1COc1ccccc1 +COc1ccc(CNC(=O)COc2cccc(C)c2)cc1OC +O=C(c1ccnc(F)c1)N(CCO)CCc1ccccc1 +CCc1ccc(C(=O)CCN2CCC(=O)CC2)cc1 +N#Cc1ccc(NC(c2ccccc2)c2ccccn2)nc1 +C=CCOc1ccc(C(=O)C(C#N)c2ccc(C(F)(F)F)cn2)cc1 +CC(C)Oc1ccccc1CN1CC(C)OCC1C +CC(CC#N)C(=O)OCc1ccc(Cl)cc1Cl +Nn1c(SCCC(=O)Nc2ccccc2)nnc1-c1ccccc1 +COC(Cc1ccc2c(c1)oc(=O)n2C)(OC)OC +Cc1cnc(NC(=O)N(C)CC2CCCC2)s1 +CC(Oc1ccccc1)C(=O)NCC1(O)CCc2ccccc2C1 +CCN(CCC#N)C(=O)CNc1ccc(-n2cnnn2)c(C)c1 +O=C(Nc1c(-c2ccccc2)nc2ncccn12)c1cccs1 +Cc1csc(C(C)NC(=O)CCC(=O)c2ccc(F)c(F)c2)n1 +CCN(CC)S(=O)(=O)c1cccc(NC(=O)Cn2cccn2)c1 +CC(=O)Nc1ccc(F)c(NC(=O)C2CCN(C(=O)C3CC3)CC2)c1 +CC(=O)Nc1cccc(NC(=O)COc2ccccc2CO)c1 +Cc1cc(C)cc(OCC(=O)Nc2cccc(C(=O)NC(C)C)c2)c1 +C=CCCOC(C)C(=O)Nc1ccc(C)cc1C(=O)NC +CCOC(=O)C1(C)CCN(C(=O)Nc2c(C)noc2CC)C1 +O=C(Cn1ccc2ccc(F)cc21)Nc1cccnc1 +COc1cccc(N2CC(C(=O)Nc3ccnn3C(C)C)CC2=O)c1 +O=S1(=O)CCCCN1c1ccc(C(F)(F)F)cc1 +N#CCCSc1nccn1Cc1ccc(F)cc1 +COc1ccccc1CCNC(=O)c1ccnc(OC(C)(C)C)c1 +Cc1sc(-c2ccco2)nc1C(=O)OC(C)c1ccccn1 +COc1ccc(COc2ccccc2C(C)O)c(OC)c1 +CC(Cn1c(=O)oc2ccccc21)NC(=O)CCn1cnnn1 +COc1ccc(C(=O)C(C)OC(=O)C2CC3CCCC(C2)C3=O)cc1 +Cc1cccnc1CC(C)NC(=O)Cn1c(=O)cc(C)c2ccccc21 +Cc1ccc(C(=O)Nc2ncccc2OCCCC#N)c(C)c1 +COc1cccc2c(C)nc(Nc3nc(C)c(C)c(=O)[nH]3)nc12 +COCCN1CC2(CCC1=O)CCN(C(=O)C1CC=CCC1)CC2 +CC(C)C(C(=O)NCc1ccncc1)n1nnc2ccccc2c1=O +N#Cc1ccc(CCC(=O)NC2CCCc3occc32)cc1 +COc1cc2cccc(O)c(=O)c2c(OC)c1OC +O=C(CNC(=O)CC1CCCCC1)NCCn1cnc2ccccc21 +COC(=O)c1cc(CN2CCOCC2)ccc1O +CCCNC(=O)Cn1ncc2c3ccccc3n(C)c2c1=O +O=C(Cc1ccc(Cl)cc1)Nc1ccc(N2CCNC2=O)cc1 +Cc1cccc(C(=O)N2CCCC3(CCC(=O)N(C4CC4)C3)C2)c1O +Cc1ccccc1COC1CCN(C(=O)CCc2nc[nH]n2)CC1 +CCNC(=O)CNC(=O)Nc1c(C)noc1CC +COCCc1noc(COC2CCCN(C(=O)c3cnccn3)C2)n1 +CCOc1ccc(C(=O)Nc2cc3c(cc2C(C)=O)OCO3)cc1 +O=C(Nn1cnnc1)c1ccccc1-c1ccccc1 +COc1cccc(C(=O)Nc2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1 +COCc1nc(C(=O)OCC2CCCCO2)cs1 +CC1CN(S(=O)(=O)NC(C)c2nnc3ccccn23)CCO1 +N#Cc1cccc(N2CC(O)CC2c2ccc(C(F)(F)F)cc2)n1 +COc1ccc2oc(-c3ccc(CNC(C)=O)cc3)nc2c1 +Cc1c(CCC(=O)N2CC(C)(C)Sc3ccccc32)cnn1C +Cc1cccc(NC(=O)C2CC3CCC2O3)c1C(N)=O +CC(C)Cc1cc(C(=O)N(CC2CCCO2)c2ccncc2)[nH]n1 +Cc1cc(C)c(NCC(=O)NCCc2ccccc2)c(C)c1 +OCc1nnn(Cc2cccc(F)c2)c1C(F)(F)F +Fc1cccc(C2(c3nc(C4CCOC4)no3)CCCC2)c1 +O=C1COc2ccc(C(=O)NCc3ccccn3)cc2N1 +O=C(Nc1ccccn1)NC1CCN(C(=O)c2ccccc2)CC1 +COc1cccc(C(=O)N2CCC(Nc3cccnc3)C2)c1OC +Cc1ccc(C)c(C(=O)N2CCN(C(=O)N(C)C)CC2)c1 +CCc1ccc(CNC(=O)Nc2nnc(C(C)(C)C)s2)nc1 +Cc1ccc(F)c(NC(=O)C2CCCN2S(C)(=O)=O)c1 +Cc1cc(-c2ccc(Br)cc2)[nH]c(=O)c1C#N +CC(=O)C1C(c2cccc(F)c2)c2c(noc2C)CC1(C)O +CC(C)c1cc(N2CCCC(N3CCNC3=O)C2)nc(N(C)C)n1 +COc1cc(C)c(S(=O)(=O)C(C)c2ccccc2)cc1OC +CCCc1nnc(NC(=O)NCc2ccccc2F)s1 +CC(NC(=O)c1cnn(C(C)(C)C)c1)c1nc2ccccc2n1C +Cc1nc(C(=O)N2CCOC(c3nc(C(C)C)n[nH]3)C2)ccc1C#N +CCOc1ccc(NS(=O)(=O)c2cc(C)sc2C)cc1 +COC(=O)CC1CCCCN1C(=O)c1cc(Cl)ccc1Cl +COc1ccc2[nH]cc(CC(=O)Oc3ccccc3OC)c2c1 +O=C(Nc1cccc2ncccc12)c1nc(-c2cnccn2)no1 +COCCSc1nnc(COc2c(Cl)cccc2Cl)n1N +O=C(NCCO)Nc1ccc(OC(F)F)c(F)c1 +CCOC(=O)C1=C(C)N=C(C)C(C(=O)OCC)C1c1ccc(C)o1 +CCCCCNC(=O)C1CSc2nc(C)c(CC)c(=O)n2C1 +CCOC(=O)c1[nH]c(C)c(C(=O)N(C)Cc2ccccc2OC)c1C +Cc1cc(C(=O)NCC(=O)NCc2nc3ccccc3n2C)nn1C +Nc1ccc2c(c1)CN(c1ccccc1Br)C2 +CC(=O)c1c(C)[nH]c(C(=O)CN2CCN(C(=O)C3CC3)CC2)c1C +CC1C(=O)N(c2ccc3c(c2)CCC3)CCN1C(=O)C(C)(C)C +COCCNC(=O)CN(C)C(=O)Cc1c[nH]c2ccc(Cl)cc12 +O=C(Nc1c[nH]cc(Br)c1=O)C1CC1c1ccco1 +Nc1ccnc(COc2cc(Cl)ccc2Cl)n1 +Cc1ccc(CN(C)C(=O)C2(C)CC2(Cl)Cl)o1 +CNc1ccc(C(=O)N(C)C(C)C(C)(C)C)cc1C +Cc1ccc(N)c(S(=O)(=O)NC(C)CO)c1C +CC(NC(=O)c1ccccc1)C(=O)Nc1ccc(Cl)cc1 +Cn1nc(CNS(=O)(=O)Cc2cccc(F)c2)cc1-c1ccco1 +COCC(=O)Nc1ccccc1C(=O)Nc1ccc2c(c1)OCO2 +CC(CNS(=O)(=O)c1cnn(C)c1)CN1CCCC1=O +Cc1ccc(NCC(=O)Nc2ccc(N3CCCC3=O)cc2)cc1F +CCCC(=O)Nc1ccc2c(c1)CCN2C(=O)c1cccnc1 +CN(CCN1CCCC1=O)C(=O)c1ccc2ccccc2n1 +Cc1c(C(=O)NCCNC(=O)c2ccco2)oc2c(Cl)cccc12 +CCC(C)Nc1nnc(-c2cc(C)nn(C)c2=O)s1 +COc1ccccc1CN1CCN(C(=O)Nc2nc(C)cs2)CC1 +CC1CN(S(=O)(=O)c2ccc(F)cc2Br)CCO1 +C#CCNC(=O)N(C)CCOc1ccccc1F +CC1CCCC(C(=O)NC(C(N)=O)C(C)(C)C)C1 +Cc1nc2ccccc2c(=O)n1CCC(=O)NCc1cccs1 +Cc1ccc(C(=O)N(Cc2ccccc2F)CC2CCCO2)cc1 +Cc1csc(C2CCCN(C(=O)CCc3cccnc3)C2)n1 +CC(=O)NCC1NCCc2cc(Cl)c(O)cc21 +NC(=O)CSc1nnnn1Cc1cccs1 +O=C(OCCCc1cccnc1)C1CCCN1C(=O)c1cccs1 +COc1cc(NC(=O)N2CCCC2c2c(C)noc2C)cc(OC)c1 +CCN(CC(C)C#N)C(=O)c1cc(F)cc(Br)c1 +CN1CCc2c(c3ccccc3n2-c2ccccn2)C1 +O=C(Nc1ccc(-c2ncc[nH]2)cc1)c1ccnc(OC2CCC2)c1 +O=C1CCc2cc(OC(=O)CCCNC(=O)c3ccco3)ccc2N1 +c1csc(CN(c2ncnc3ccsc23)C2CC2)c1 +COc1ccc(S(=O)(=O)N(C)c2ccccc2F)cc1C +CCC1c2ccsc2CCN1C(=O)Nc1cnn(CCOC)c1 +CCC(=O)N1CCCC(C(=O)Nc2cnn(C)c2)C1 +COc1ccccc1NC(=O)N(C)Cc1ccsc1 +Cc1ccc2sc(NC(=O)c3ccno3)nc2c1C +CCc1nc(CNC(=O)C2COc3ccc(F)cc3C2)cs1 +CCC(CC)N(CCO)c1ccc(F)cc1C(C)=O +Cc1cccc(C(C)C)c1NC(=O)NCc1ccccn1 +CC1CCCCC(=O)C1c1cn(C)c2ccccc12 +O=C(CNC(=O)NC1CCCC(C(F)(F)F)C1)Nc1cccnc1 +Cc1noc(CCNC(=O)c2ccnc(OC3CCC3)c2)n1 +CCNC(=O)Nc1cccc(NC(=O)CCSc2ccccn2)c1 +CC(C)OC(=O)C1CCCN1Cc1ncccc1C(F)(F)F +NC(=O)c1ccc(-c2nnn(CC#Cc3ccc(Cl)cc3)n2)cc1 +CCC(CO)Nc1ncc(Br)c2c(N)ccc(C)c12 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)NCCOc1ccccc1 +CCC(CO)NS(=O)(=O)c1ccc(Cl)cc1C +CC(C)C(=O)N1CCN(c2nc3ccc(F)cc3s2)CC1 +CCC(C)NC(=O)COc1ccc(C2OCCCO2)cc1N +CN(C)c1ccc(S(=O)(=O)N(C)C)cc1NC(=O)C1CCCC1 +COc1ncccc1C(=O)N1CCC2(CC1)OCCO2 +CC(NS(=O)(=O)c1cccs1)c1ccncc1 +Cc1cccc(C(=O)Nc2cccc(-c3nncn3C)c2)c1 +Cc1cccc(NC(=O)C2CCCN2C(=O)c2cccc3[nH]ccc23)n1 +Cc1nn(CC(=O)NC2Cc3ccccc3C2)c(=O)c2ccccc12 +CCn1cc(C#N)c(=O)n(Cc2ccccc2C#N)c1=O +O=C(Nc1cc(F)ccc1Br)N1CCOCC1C1CC1 +NC(c1ccc2[nH]c(=O)oc2c1)C(F)(F)C(F)(F)F +Cc1cc(-c2ccc(Br)cc2)c(C#N)c(=O)n1C +CC(C(=O)Nc1ccccc1C#N)n1cc(Cl)cn1 +NC(=O)CCN(Cc1ccccc1)C(=O)Cc1cccs1 +O=C(NC1CC(=O)N(c2ccccc2)C1)c1ccnc(-n2cncn2)c1 +O=C(Cc1noc(C2CC2c2ccccc2)n1)NC1CCCC1 +O=C(OCCOc1cccnc1)c1ccc(-n2cccc2)nc1 +CN1CCN(C(=O)Nc2cccnc2-n2cncn2)Cc2ccccc21 +COc1ccc(C(C)NC(=O)NCCc2csc(C)n2)cc1OC +CCC(=O)Nc1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +CC(=O)Nc1cccc(-c2nnc3n2CC(C)S3)c1 +COCCOC(=O)c1nnc2nc(SC)nn2c1C +CCCCCC(=O)NC1CCN(S(=O)(=O)CC)CC1 +Cc1nc[nH]c1-c1nccn1C1CCCN(C(=O)c2ccco2)C1 +CC(=O)c1ccc2c(c1)N(CC(=O)N1CCCC1)C(=O)C(C)(C)O2 +COc1ccc(OCC(=O)Nc2noc(-c3ccccc3)n2)cc1 +Cc1c(C2CC2)n[nH]c1NC(=O)C1CC1c1ccc2c(c1)OCCO2 +CN(Cc1cccc(F)c1)C(=O)Nc1ccc2[nH]nnc2c1 +CS(=O)(=O)N1CCc2ccc(C(=O)NCCc3cccnc3)cc21 +COC(=O)COc1cc2c(cc1C(C)c1ccc(O)cc1)OCO2 +O=S(=O)(c1cccc(Cl)c1)N1CCN(C2CC2)CC1 +Clc1cccnc1-c1cc(NCc2ccncc2)nc2[nH]ccc12 +Cc1cccc(C)c1NC(=O)Nc1ccccc1F +CCC(NC(=O)c1csc(C(C)=O)c1)c1ccc(F)cc1 +O=C(CC(c1cccs1)C1CCCCC1=O)c1ccco1 +CCCCN(CC(N)=O)S(=O)(=O)c1ccc(F)cc1C +Cn1cc(C#N)cc1C(=O)NCc1nnc(-c2ccc(Cl)cc2)o1 +O=C(NCc1ccccc1OC(F)F)c1scnc1C1CC1 +CC(c1ccco1)N(C)C(=O)Nc1cnn(Cc2ccccc2)c1 +CN(C)c1ccc(-c2noc(C(=O)NC3CCCC3)n2)cc1 +CC(C)CC(=O)NC(C(=O)N(C)Cc1cccnc1)C(C)C +CC1CN(C(=O)c2ccc(Cl)cc2)c2ccccc2NC1=O +CCC(=O)N1CCN(c2nnc(SCC(=O)NC)s2)CC1 +CS(=O)(=O)NC1CN(C(=O)c2ccco2)CC2CCCOC21 +CCCN1CCN(C(=O)Cc2ccccc2Cl)CCC1=O +CCCn1ccc(C(=O)Nc2nc(C)c(C)s2)n1 +CCCNS(=O)(=O)c1c(C)nn(-c2ccccc2)c1C +CCOc1cccc(NCC(=O)Nc2cccc(C(=O)N(C)C)c2)c1 +O=C(CNc1cccc(F)c1)NCCc1nc2c(s1)CCCC2 +CC(NS(=O)(=O)c1ccc(F)c(C(F)(F)F)c1)C(=O)N(C)C +CCC(C(=O)Nc1cc(N)ccc1OC)c1ccccc1 +COc1ccc(Cl)cc1NCC(=O)N(C)C(C)C +Cc1noc(C)c1CCC(=O)NCc1cc(-c2ccccc2)on1 +Cc1ccc(C(C)C)cc1S(=O)(=O)N1CCCC(=O)C1 +Cc1cc(-n2cnnc2)cc(C)c1NC(=O)C(C)C +COc1ccc(O)c(C(=O)N(Cc2ccc(F)cc2)C2CC2)c1 +CCOC(=O)CCC(C)NC(=O)Nc1cc(Cl)ccc1F +N#Cc1cccnc1NCCOC(=O)c1cnc(C2CCCO2)s1 +CCC(O)c1nc(Cc2ccccc2)c(N2CCOCC2)o1 +CN(C)C(=O)CCCn1ccc(NCc2ccncc2)n1 +Cc1noc(COCC(=O)N2CCCC(CCC(N)=O)C2)n1 +CC(CCc1ccco1)NC(=O)Cc1coc(-c2cccs2)n1 +COc1ccc(-n2cnnc2SCc2cccc(F)c2)cc1 +O=c1oc(C(O)=NCc2cccnc2)cc2ccccc12 +COc1cc(N2CCC(=O)C2)c(OC)cc1Cl +CC(NC(=O)CNC(=O)CC(C)(C)C)c1ccccn1 +CCCC(=O)Nc1ccccc1NC(=O)Cc1cccs1 +CCOc1ccccc1C(=O)N1CCN(CCOC)C(=O)C1 +CC(=O)c1ccc(C(=O)NC2CCCN(c3ncccn3)C2)s1 +N#CCCCOC(=O)c1cccc2c1NC(=O)C2=O +CC(Sc1nc2ccsc2c(=O)n1C)C(=O)N1CCCCC1 +O=C(CSc1nc2ccccc2[nH]1)NCC1Cc2ccccc2O1 +COc1ccc(S(=O)(=O)N(CCO)C2CCCCC2)cc1 +Cc1ccc(CNC(=O)NC2CCCCNC2=O)s1 +CCCCCNC(=O)Nc1ccc(N(C)C(C)=O)cc1 +Cn1nnnc1SCC(=O)Nc1ccccn1 +COC(=O)CCNC(=O)CNC(=O)c1ccoc1C +CCCOc1ccc(C(N)=O)cc1Br +Cc1ccc(CC(=O)Oc2ccc(Oc3ccccn3)cc2)cn1 +O=C(NCc1cscn1)N1CCCCCC1c1ccco1 +Cc1nnc(SCc2cc(Br)cs2)o1 +CC(C)c1nc(NC(=O)c2ccn3nnnc3c2)n[nH]1 +CC(CNC(=O)C1CC(=O)N(c2ccc(F)cc2)C1)c1ccccc1 +Cc1n[nH]cc1CNC(=O)CCNC(=O)c1ccccc1 +COc1ccc(NC(=O)Cn2c(=O)[nH]c3ccccc32)cc1Cl +Cc1noc(C)c1CC(=O)N1CC2(COC(C)(C)OC2)C1 +Cc1cc(C(C)NS(=O)(=O)N2CCC(C)CC2)c(C)o1 +Cc1oc(-c2ccccc2Cl)nc1CN1CCNC(=O)C1 +Cn1ncc(-c2ccccc2)c1C(=O)NC1CCCC1 +NC(=O)c1cccc(CNC(=O)c2ccc(Br)cc2)c1 +O=C(C1CC2CCC1O2)N(Cc1cccs1)Cc1cccs1 +Cc1ccc(-c2nnc(COc3ccc4c(c3)CCC(=O)N4)o2)cc1 +COc1cccc(NC(=O)CCn2ccc3cc(OC)ccc32)c1 +N#Cc1ccc(N2CCC(OCCCc3ccccc3)C2)nc1 +O=C(NCc1ccc2c(c1)OCCO2)c1cncn1-c1ccccc1 +COC(=O)C1CCCCN1C(=O)c1ccc(C)n1C +COc1ccc(C(=O)N(C)Cc2ccncc2)cc1Br +O=C(c1cccc2nccnc12)N1CCCCC1c1ccc(F)cc1 +CN(C)C(=O)CN(C)C(=O)c1cc(N)ccc1F +O=C(Nc1ccc(Cl)cc1)c1csc(-c2ccncc2)n1 +c1ccc(-n2ncc3c(NC4CCCCC4)ncnc32)nc1 +CN(Cc1cccs1)c1ncnc2c1cnn2CCO +Cc1cnc(C2NCCc3cccc(Cl)c32)cn1 +CCCNC(=O)NCc1noc(-c2cccs2)n1 +CCC(=O)NCC(=O)NCc1noc(-c2ccsc2)n1 +OC1CN(c2nccc(C3CCCC3)n2)CC1N1CCOCC1 +COc1ccc(Br)cc1CNC(=O)CC1CCCO1 +CN(Cc1nnc2n(C)c(=O)c3sccc3n12)c1ccc(F)cc1 +COc1cc(Cl)ccc1C(=O)N1CCC2(CCCO2)CC1 +CCCC(C)NC(=O)c1ccnc(-n2cncn2)c1 +COc1ccc(F)c(NC(=O)CCOCC(F)(F)F)c1 +c1ccc2nc(N3CCCC3c3nnc4n3CCCCC4)cnc2c1 +O=C1NCCCC1C(=O)NCCc1c[nH]c2ccc(O)cc12 +COc1ccc(F)c(NCC(=O)NCC(F)(F)F)c1 +O=C(NCCn1cccn1)C1CC1c1ccccc1 +CCOc1ccccc1NC(=O)CN1CCOc2ccc(N)cc21 +COCCCNC(=O)Nc1ccccc1OC(C)C +O=C(CCCc1nc(-c2ccco2)no1)Nc1ccc(Cl)cc1 +O=C(CCc1ccccc1)Nc1cccc(-c2nnco2)c1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)N(C)CCC(F)(F)F)c1 +COCC(=O)NCc1ccc2c(c1)CCN2C(=O)c1ccccc1 +Cc1cc(Cl)ccc1NC(=O)C(C)NC(=O)c1ccco1 +COc1ccc(OC)c(CCNC(=O)c2ccoc2)c1 +CCN(CC)S(=O)(=O)CCNC(=O)N(C)C1CCCCCC1 +N#Cc1ccc(-c2noc(CSc3ccc4c(c3)CCC4)n2)nc1 +CCCOc1ccc(CCC(=O)Nc2cccc(O)c2)cc1N +CCCCCn1ccc2nc3ccn(-c4ccn[nH]4)c(=O)c3cc2c1=O +Cc1cc(F)ccc1NC(=O)N(C)C(C)c1ccccn1 +Cc1cc(C(=O)NCc2ccc3c(c2)OCCO3)sc1C +CCCCOC(C)C(=O)NC(C)(C)c1nc(C)c(C)s1 +CCN(CCO)C(=O)C1CCC(=O)N(Cc2ccccc2OC)C1 +CC(C)(C#N)c1ccc(NC(=O)NCCC2CCCCO2)cc1 +COc1ccc2c(CC(=O)Nc3ncc(C(N)=O)s3)coc2c1 +O=C(Nc1ccc2c(c1)OCO2)C1CC2CN(CC3CC3)CC1O2 +Cn1ncc2c(Nc3ccc4c(c3)OCCCO4)ncnc21 +Cc1cnn(C2CCCN(C(=O)C(C)c3cc(C)oc3C)C2)c1 +COC(=O)c1ccsc1NC(=O)c1cc(C)no1 +Cn1ccc(NC(=O)Cc2cn(C)c3ccccc23)n1 +Cc1nn(CC(=O)Cc2ccccc2)c(C)c1Br +CC(=O)Nc1ccc(CC(=O)Nc2cccc(C(N)=O)c2)cc1 +Cc1ccc(S(=O)(=O)NC(C)CC(C)C)cc1N +NC(=O)c1ccc(C(=O)NC(c2ccccc2)c2ccc(F)cc2)cc1 +COc1ccc(-c2ccc(S(N)(=O)=O)cc2)c(S(N)(=O)=O)c1 +COCC(=O)Nc1cccc(-c2cn3nc(OC)ccc3n2)c1 +COc1ccc(NC(=O)Nc2ccc3c(c2)CCO3)cc1 +Cc1ccc2nc(C(=O)NCc3noc(-c4ccccc4)n3)[nH]c2c1 +CCNC(=O)CNC(=O)c1cc(C(C)(C)C)n[nH]1 +C#CCNC(=O)C1(C(F)(F)F)CCN(Cc2ccccc2)C1 +O=C(CCO)NC1CC(=O)N(Cc2cccc(F)c2)C1 +c1ccc(-c2ncc(CN3CCN(Cc4cccs4)CC3)[nH]2)cc1 +Nc1c(C(=O)NC2CCCC2)sc2nc(-c3ccncc3)ccc12 +O=C(Nc1cccc2c1NCCC2)C1CCCCO1 +Cc1ccc(=O)n(C(C)C(=O)N2CCC(C)CC2)n1 +CC1CCC(N(C)C(=O)CNC(=O)c2ccccc2)CC1 +Cc1cc(C(=O)Oc2ccc3c(c2)CCC(=O)N3)c(C)o1 +COc1ccc(CNC(=O)c2cc3cccc(OC)c3o2)cc1O +Cc1csc(CNc2cccc(OCC(F)(F)F)c2)n1 +Cc1cccc(CN(C(=O)c2cc3ccccc3oc2=O)C2CC2)c1 +C#CCN(CC#C)C(=O)c1cc(S(N)(=O)=O)cc(Cl)c1F +CCN(Cc1ccccc1)C(=O)CNc1cccc(C(=O)NC)c1C +O=S(=O)(Cc1cccc(Cl)c1)NCc1ccccn1 +COc1cccc(OCc2cc(N)n(CCO)n2)c1OC +CCc1nc2n(n1)CCCC2NC(=O)COc1ccc(F)cc1 +O=C(Nc1cccc(O)c1)c1ccc(NC(=O)c2ccco2)cc1 +CN(Cc1ccccc1N1CCOCC1)S(N)(=O)=O +NC(=O)c1cc(N)ccc1NCCc1ccccn1 +CCC(=O)c1ccccc1NC(=O)c1ccccc1 +CC(=O)Nc1ccccc1OCc1cccc(N)c1 +CCCN(CCC)S(=O)(=O)c1cncc(N)c1 +O=C(NCc1ccccc1)NCC(O)(c1ccccc1)C(F)(F)F +Cc1noc(CCC(=O)N2CCC(CO)CC2)n1 +CCCNC(=O)c1cccc(NC(=O)CNc2ccc(F)cc2)c1 +C=CCc1cc(C(=O)Nc2ccncc2)cc(OC)c1OC +CC(c1ccncc1)N(C)Cc1cnc(C(C)(C)C)nc1 +CCN(CC(C)C#N)C(=O)CNc1cccc(Cl)c1-n1cccn1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)COCCOc1ccccc1 +Fc1cc2c(cc1C(F)(F)F)CCNC2c1ccncc1 +Cc1cc(C(=O)OC2CN(c3nc4ccccc4s3)C2)no1 +CC(=O)N1CCCC1c1nc(N)ncc1-c1ccc(Cl)cc1 +Nc1cc(N)nc(SCc2ccc(C(=O)N3CCCC3)cc2)n1 +c1ccc(C(Nc2ncnc3n[nH]cc23)c2ccccc2)cc1 +Nc1ccc(Cl)c(C(=O)OCC(=O)c2ccc[nH]2)c1 +CCCCC(O)c1cc(C)c2c(c1)C(CC)C(=O)N2 +CCCC1CN(C(=O)Nc2ccc3c(c2)oc(=O)n3C)CCO1 +COc1cc(C)ccc1OCC(O)CNc1ccc(C)cc1 +CN(C)C1C(OC2CC2)=CC=NC1NS(C)(=O)=O +Cc1oncc1C(=O)c1ccc(Cl)cc1Cl +CCC(C)C(C)NC(=O)c1cc(Cl)ccc1N +N#Cc1ccc(NC(=O)N2CCN(CC(=O)N3CCCC3)CC2)cn1 +O=C1NCCNC1Cc1cccc(-c2cccnc2)c1 +N#Cc1ccccc1N1CCN(C(=O)c2cccnc2)CC1 +Cn1c(=O)[nH]c(=O)c2c1nc1n2CCN1c1cccc(Cl)c1 +CCN(CC)C(=O)c1csc(-c2cc3ccccc3n2C)n1 +CNC(=O)c1ccsc1NC(=O)COc1ccccc1C +Cn1ccnc(NC(=O)Nc2cnn(Cc3ccccc3)c2)c1=O +CCC(C)NC(=O)NCc1cccc(C(=O)NC)c1 +CCCOc1ccc(Cl)cc1NC(=O)c1ccc(=O)n(C)c1 +CCc1nnc2c(NC(=O)CCc3ccc(OC)cc3)cccn12 +CC(C)(C(=O)NCc1csc(=O)[nH]1)C1CCCC1 +C=C(C)Cn1nnc(CO)c1COc1ccccc1OC +CCOC(=O)c1c(-c2cccc(Br)c2)noc1C +CN1c2cc(Cl)ccc2Oc2cc(N)c(N)cc21 +Cc1noc(C)c1C(=O)NCC1(O)CCCc2ccccc21 +C=C(C)Cn1c(SCC)nc2c1c(=O)[nH]c(=O)n2C +CC(C)Cn1ccnc(N(CCCO)C(C)C)c1=O +Cn1c(=O)oc2cc(NC(=O)c3ccc4nncn4c3)ccc21 +Cc1cncc(NC(=O)N(C)CC2CCCCO2)c1 +Cc1c(NCc2cc(Br)ccc2F)cccc1C(N)=O +CC(C)(C)OC(=O)N1CCCC(c2ccc(N)cc2F)C1 +Cc1nc(-c2ccccc2C)n(CC(C#N)CCC#N)n1 +CC(=O)N1CCC2(CC1)C(=O)Nc1cc(N)ccc1N2C +CCCC(C)CNC(=O)C(N)c1ccc(C)c(F)c1 +Oc1ccc(C2NCCc3ccc4[nH]ccc4c32)cc1 +O=C(Nc1ncn[nH]1)C1CCCN(c2cc(-n3cncn3)ncn2)C1 +CCn1nccc1C1CCCN1C(=O)c1cc(F)c(F)cc1Cl +CCOC(=O)c1sc2nc(C)nc(NCC(=O)N(C)C)c2c1C +Cc1cc(C(=O)Nc2ccccc2C(N)=O)c(C)cc1Br +Cc1ccccc1C(=O)NCc1cc(=O)oc2ccc(F)cc12 +O=C(NC1CCCCC1)N1CCN(Cc2nc3ccccc3[nH]2)CC1 +Cc1c(C(=O)N(C)C2CCCCC2)cnn1-c1ccccc1 +COCC(=O)N1CC(C)C2(CCN(c3ccsc3)C2=O)C1 +O=C(Nc1cccc(-c2nc[nH]n2)c1)c1ccc2ccccc2n1 +CCOCc1ccc(CNC(=O)N2CCCN(C(=O)CC)CC2)cc1 +Cn1nnc2c(SCc3cccc(Cl)c3)ncnc21 +O=C(NCc1nc(-c2ccccc2)cs1)Nc1cccnc1 +C#Cc1cccc(N(CC)Cc2cccc(C(=O)NC)c2)c1 +CCc1nc(COC(=O)C2CC3CCC2O3)cs1 +CC(=O)NCCCc1nc2ccccc2n1Cc1ccc(C)cc1 +O=C(Cc1ccc(-c2ccccc2)cc1)NCC(O)c1ccsc1 +Cc1cc(NC(=O)Cn2nc(-c3cccs3)n(C3CC3)c2=O)no1 +CCOc1cccc2c1C(c1cnccc1Cl)NCC2 +CC(NC(=O)CSc1ccccc1F)C(=O)N1CCCCC1 +O=C(OCc1ccccc1)C1CN(CC(F)(F)F)C1 +Cc1cc(C(C)NC(=O)CCN2C(=O)COc3ccccc32)c(C)o1 +CC(=O)N1CCCC1C(=O)NCCc1cc(Cl)cc(Cl)c1 +NC(=O)Cn1cc(NC(=O)NCC2CCCc3ccccc32)cn1 +C(#Cc1cc(N2CCOCC2)cc2nonc12)c1ccccc1 +COc1ccc(NC(=O)c2cnn(CC(C)C)c2C2CC2)c(C)n1 +COc1ccc(CN2CC(C(=O)NCCC(C)C)CC2=O)cc1 +CCOc1ccccc1NC(=O)c1ncccc1O +O=C(CSc1nncs1)N(Cc1ccccc1)C1CC1 +O=C(Nc1cc(-c2ccncc2)n[nH]1)c1cccc(-n2cnnn2)c1 +Cc1ccc(-n2nnc(C(=O)N(C)c3ccccc3)c2C)cc1 +O=C(NCC1CCN(C(=O)c2ccoc2)CC1)c1ccccc1Cl +COc1cc(C)c(C(=O)N2CCCC2Cc2ccccc2)cc1OC +COc1ccc(C(=O)Nc2ccccc2C(N)=O)c(OC)c1 +Cc1ccc(OCCCC(=O)Nc2nonc2C)cc1C +CC(C)CN1CN=C(NS(=O)(=O)C(C)C)NC1 +COCc1nnc(NC(=O)c2csc(NC(C)C)n2)s1 +Cn1cnn(Cc2ccc(-n3cccn3)cc2)c1=O +CC(C(=O)NCc1cccnc1-n1cncn1)n1cncn1 +CCNC(=O)Nc1cccc(NC(=O)Cc2c(CC)noc2CC)c1 +O=C(c1cccs1)N1CC(OCc2ccccc2Cl)C1 +O=C(NC1CCC1)c1cccc(Br)c1F +CC1(O)C(O)C(CO)OC1n1cnc2c(NC3CCCC3)ncnc21 +CCC(NC(C)=O)C(=O)N1Cc2cnc(-c3ccccc3)nc2C1 +CC(NCc1cc(Cl)c2c(c1)OCCO2)C(N)=O +O=C(COc1ccc[nH]c1=O)Nc1nccs1 +NS(=O)(=O)Nc1cccc(NC(=O)C2CCCCCC2)c1 +CCCc1noc(CSc2ncnc3sc(C)cc23)n1 +Cc1cc(C)c(CNC(=O)CCn2cncn2)c(=O)[nH]1 +Cc1cc(C)c(C)c(C(C#N)CN2CCOCC2)c1C +Cc1ccc(S(=O)(=O)N2CCCC(C(=O)NCC(C)C)C2)cc1 +COC(=O)c1ccc(N2CCN(C(=O)c3cnc(C)s3)CC2)cc1 +CC(=O)Nc1cc(F)c(S(=O)(=O)N2CCCCCC2)cc1Cl +Cc1sc(C(=O)OCCC(=O)NC2CC2)cc1N +CCNc1nc(-c2ncccn2)nc(C)c1C(C)C +COc1ccc(C(=O)c2ccc(NC(C)=O)cc2)c(OC)c1 +CCN(CC)c1nc(C)cc(C(=O)NCc2cccc(OC)c2)n1 +CCNC(=O)CCC(=O)Nc1nc(C)c(Cc2ccc(F)cc2)s1 +COC(=O)CCN(C)C(=O)Nc1cc(Cl)ccc1Cl +O=C(NCc1ccnc(-n2cccn2)c1)OCC(F)(F)F +CC(C)c1noc(CN2CCN(C(=O)C3CC3)CC2)n1 +COCCCNC(=O)C1CCC(=O)N(C)C1c1cccs1 +CCc1ccccc1NC(=O)Cn1ncc(-c2ccccc2)nc1=O +O=C(Nc1cnn(-c2ccccc2F)c1)C1Cc2cccc(F)c2O1 +CCCn1cc(NC(=O)NCc2ccc(Cl)cc2)ccc1=O +CC(=O)c1ccc(OS(=O)(=O)c2ccc(C)cc2)cc1O +C#CCC(NC(=O)CC(C)c1ccc(F)cc1F)C(N)=O +O=C(c1ccc2c(c1)OCCCO2)C1CCCCN1 +Cc1cc(C(F)F)nn1CC(=O)Nc1sc2c(c1C#N)CCC2 +Cc1cc(C)n(Cc2noc(-c3scnc3C)n2)n1 +Cc1nn(C)c2ncc(NC(=O)NCCCOC3CCCC3)cc12 +Cc1ccccc1OCCCC(=O)Nc1nnc(C2CCCO2)s1 +COc1cccc(OC)c1-c1cc(CO)c(=O)[nH]n1 +CC(C)C(=O)NCCNC(=O)N(C)Cc1c(F)cccc1Cl +Cc1cc(S(=O)(=O)Oc2c(C)nn(C)c2C)ccc1F +CCOC(=O)C(C)(Nc1ccccc1OC)C1CC1 +Cc1cc(NC(=O)C(C)Sc2ccccc2)on1 +CCCn1c(=O)c(N2CCN(C(=O)COC)CC2)nc2ccccc21 +CC(=O)c1cc2c(cc1NC(=O)CCNC(=O)c1ccco1)OCO2 +Cn1cnc2cc(C(=O)NCc3csc(-c4ccccc4)n3)cnc21 +CCC(O)(CC)Cn1c(=O)[nH]c2ccccc2c1=O +Cc1ccc2nc3n(c2c1)C(CNC(=O)c1cncnc1)COC3 +CC(C)(C)n1cc(NC(=O)Cc2cccc3cccnc23)cn1 +COCCNC(=O)c1cc2c(C)nn(-c3ccc(Cl)cc3)c2s1 +CC(NC(=O)NCc1cc2cc(F)ccc2s1)C1CCOCC1 +CCOC(=O)C(C)(NS(=O)(=O)c1ccccc1)C(C)C +CC(C)c1nc(CN2C(=O)COc3cccnc32)no1 +Cc1c(C(=O)OC(C(=O)N2CCOCC2)c2ccccc2)cnn1C +CCCN(CC(=O)Nc1ccc(Cl)cc1)C(=O)c1cc(C)nn1C +Cc1cc(C)c(NC(=O)CCNC(=O)c2cccs2)c(C)n1 +Cc1cc(C(=O)N2CCCC2C(F)(F)F)c(=O)[nH]c1C +CC(C(=O)N1CCNC(=O)C1c1ccccc1Cl)n1cncn1 +Cc1cc(=O)[nH]c2cc(NC(=O)c3cnn(-c4ccccc4)n3)ccc12 +Cn1nc(C2CCC2)cc1NC(=O)NCC(=O)NCC1CC1 +CCc1nn2c(CO)c(-c3ccc(N(C)C)cc3)nc2s1 +CCOc1ccccc1OCC(=O)NC(C)C(N)=O +Cc1nccn1-c1nccnc1C1CCCN(Cc2cccnc2)C1 +Cc1c(C)n(CC(C)C)c2ncn3nc(-c4ccncc4)nc3c12 +CCOC(=O)CN(C(=O)c1oc2ccc(OC)cc2c1C)C1CC1 +CCOC(=O)c1nc2c(s1)CCN(C(=O)OC(C)(C)C)CC2 +CN(C)S(=O)(=O)Nc1cccc(OC(=O)N2CCOCC2)c1 +Cc1cc(C)c(C(=O)N(C)Cc2cn(C)nc2C(F)(F)F)c(C)c1 +Cc1nn(C)c(C)c1CC(=O)OCCNc1cccnn1 +CCc1[nH]c(C(=O)N=c2sccn2C)c(C)c1C(=O)OC +CC(Oc1ccccc1C(F)(F)F)C(=O)NCC(N)=O +N#CCCCOc1cccc(NCc2cccs2)c1 +c1ccc(-n2cnc(SCc3cn4cccnc4n3)n2)cc1 +CC1CN(CC(O)c2ccc(C(C)(C)C)cc2)CC(C)O1 +CCCC(=O)N1CCCCC1C(=O)Nc1cc(F)ccc1OC +Oc1cccc(CNc2ccc(F)cc2Cl)c1 +CCCS(=O)(=O)NCC1CN2CCCCC2CO1 +N#Cc1cc(N2CCN(c3nccs3)CC2)ccn1 +COc1ccc2c(CN3CCOc4ccccc43)cc(=O)oc2c1 +O=C(CCNS(=O)(=O)c1ccccc1Cl)NC1CCCCC1 +NC(=O)Cc1cc(Br)c2nncn2c1 +Cc1ccc(-c2cc(CO)c(=O)n(CC(C)C)n2)cc1C +Cc1occc1C(=O)Nc1cc(S(C)(=O)=O)ccc1F +O=C(NCCCCc1ccccn1)c1cnc(C2CC2)[nH]c1=O +Cc1nnc(C(C)Sc2nnc(-c3ccc(Cl)cc3)n2N)o1 +COc1cc(C=c2sc3ncnn3c2=O)ccc1OCC(C)C +CCOC(C)C(=O)N1CCCC(c2nc3ccccc3n2C(C)C)C1 +C#CCN(C1CCCCC1)S(=O)(=O)N(C)CCC#N +Cc1ccc2c(c1F)CCNC2CCC(=O)c1ccccc1 +COc1ccc(-c2cc(C(=O)NC(C)C)nn2C)c(F)c1 +CC(=O)NCC(=O)NCCc1nc2ccccc2s1 +CCN(C(=O)c1cnn(-c2ccncc2)c1C)C(C)c1cccnc1 +O=C(NC(CC(=O)N1CCOCC1)c1ccccc1)c1ccccc1 +CNC(=O)C(CC(C)C)NS(=O)(=O)c1ccc(Cl)cc1 +COc1ccccc1NC(=O)N1CCc2[nH]cnc2C1c1ccncc1 +CN(CC1Nc2ccccc2S1)C(=O)Cc1c[nH]c2ccccc12 +O=C(CCNC(=O)c1ccco1)NCc1ccc(-c2ccn[nH]2)cc1 +Cc1cccc(CS(=O)(=O)NCC2(O)CCc3ccccc32)c1 +CCOc1cc(NC(=O)c2cc(C)sc2C)ccc1OC +Cc1ccc(CNC(=O)C(C)(C)c2ccccc2F)cn1 +CCCNC(=O)c1cccc(NC(=O)N(C)C(C)c2ccco2)c1 +CCOCCNC(=O)c1cc(S(=O)(=O)C(C)C)ccc1F +COC(=O)CN(Cc1cnc2ccc(C)cn12)C(C)C +Cc1ccc(CNC(=O)c2cc(F)c(F)cc2Cl)n1C +Fc1cc2c(cc1F)C(C=Cc1ccncc1)NCC2 +O=C(c1ccncc1)N1CCCC1c1cncc(-n2ccnc2)n1 +CN(CC1CC1)C(=O)Nc1cc(C(F)(F)F)ccc1-n1cccn1 +CN(Cc1ccncc1)C(=O)Nc1ccccc1OCC1CC1 +Cn1c(CNCCc2cccs2)cc(=O)n(C)c1=O +Cc1cc(O)ccc1NCc1ccc(C#N)cc1F +CC(=O)c1csc(NC(=O)c2ccc3cc[nH]c3c2)n1 +CC(Nc1cccc(NC(=O)CO)c1)C(=O)NCc1ccc(F)cc1 +COc1c(Cl)cccc1NC(=O)c1cc(C)n[nH]1 +CCCNC(=O)CSc1nnc2cc(C)c3ccccc3n12 +CC(C)c1nnc(NC(=O)Cc2ccc[nH]2)s1 +O=C(NCC1CCCOC1)c1cc(Br)cn1C1CC1 +O=C1CC(C(=O)OCCNc2cccnn2)c2ccccc2N1 +CCC1c2ccsc2CCN1C(=O)c1cccc(OC)c1O +Cc1ccc(OC(=O)C(C)Sc2nnnn2C2CC2)c(Cl)c1 +COC(=O)CC(NC(=O)c1cccc(NC(C)=O)c1)c1ccccc1 +O=C(CN1CCOC1=O)N1CCC(Cn2ccnc2)CC1 +NC(=O)c1ccc(NC(=O)COc2ccc(CO)cc2)cc1 +CCCOCC(=O)Nc1nc(C)c(C(=O)OC)s1 +Brc1cccc(-c2nc(C3CC3)no2)c1 +CCCOc1ccccc1NC(=O)N1CCC(OCC(C)C)CC1 +Cc1csc(S(=O)(=O)C(C)C(=O)N(C(C)C)C(C)C)n1 +COC(=O)c1nsc(C(=O)Nc2c(C)cccc2C)c1N +CC(C)C(NC(=O)c1ccc(S(C)=O)cc1)c1ccccc1 +CN(CC1(CO)CCOCC1)C(=O)COCc1ccccc1 +COCCCNC(=O)c1cc2c(s1)-c1ccsc1CC2 +CCn1nnc2cc(C(=O)Nc3ccccc3)ccc21 +COC(=O)C(NC(=O)c1cc2ccccc2[nH]1)C(C)C +CC(C)(C)c1ccc(C(=O)n2nc(C(F)(F)F)nc2N)cc1 +O=C(NCC1CCCO1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +Cn1cnc(CNC(=O)Nc2cccc(OCc3cscn3)c2)n1 +CCC(C)NC(=O)c1ccc(NC(=O)CC(C)C)cc1 +CC(C)COC(=O)N1CCN(C(=O)c2cccc3ccccc23)CC1 +Cc1ccc(NS(=O)(=O)c2ccc(F)cc2F)cc1F +CCCCNC(=O)NCc1cc(-c2ccccc2)no1 +CC(=O)N1CCCC1c1cccc(C(=O)Nc2cnccn2)n1 +CCC(C)NC(=O)Cn1c(=O)ccn(Cc2cccc(F)c2)c1=O +Cc1ccc(OCC(=O)N(C)C(C#N)c2cccnc2)cc1 +COc1ccc(CC(C)CN(C)C(=O)NCc2ccn(C)c2)cc1 +COC(=O)c1c(C)nn(CC(=O)Nc2ccc(C)cc2)c1C +COc1ccccc1CCc1nc(CC#N)c(C)o1 +COCCS(=O)(=O)N1CCC(Nc2ccccc2OC)CC1 +COC(=O)c1cc(S(=O)(=O)NCc2ccc(F)cc2)cn1C +CCc1ccccc1NC(=O)CSc1nnc(C2CC2)n1C +Cc1[nH]c2ccccc2c1C(=O)CN1CCN(c2ncccn2)CC1 +Cc1cc(C)c2c(c1)NC(NCC(C)O)=NS2(=O)=O +Cc1ccc(OCc2c(C#N)nnn2-c2ccccc2)cc1 +N#Cc1ccc(NC(=O)C2(c3cccc(F)c3)CCOCC2)cc1 +COc1ccc(OC)c(C(=O)NCCCn2cnc3ccccc32)c1 +COCCNC(=O)c1cccc(NC(=O)c2cccc(C)c2)c1 +CN(C)C(=O)c1cccc(C2CCN(c3ncccn3)CC2)n1 +c1ccc(-c2nnn(Cc3noc(-c4ccsc4)n3)n2)cc1 +COc1cccc(SC(C(N)=O)c2ccccc2)c1 +Cc1csc(NC(=O)NCCCSc2ccccc2)n1 +CCN(CCC(=O)OC)C(=O)c1cc(F)c(F)c(F)c1F +CN(Cc1ccccc1)C(=O)c1ccc2ncccc2n1 +CCCOCC(=O)NCC1(c2ccccc2Br)CC1 +CNC(=O)Nc1ccc(NCc2sccc2C)cc1 +CC(C)(C)c1nnc(N2CCN(C(=O)c3cccnc3)CC2)s1 +CSc1ccccc1Nc1ncnc2n[nH]cc12 +CCCC(NC(N)=O)C(=O)N1CCc2cc(F)ccc2C1 +CC(=O)Nc1ccccc1OCc1c(C)noc1C +Cc1n[nH]c(C)c1NC(=O)CSc1ccc(N)cn1 +COc1ccccc1NC(=O)c1nnn(-c2ccccc2)c1C1CC1 +Cc1ccc(OCC(=O)N(C)C(C#N)c2ccncc2)cc1 +CCCCNC(=O)Nc1ccccc1N1CCCC1 +Nc1ccccc1N1CCN(Cc2cccc(Cl)c2)CC1 +Cc1ccc(C(O)c2nnc(C(O)c3ccc(C)cc3)nn2)cc1 +CN(CC(=O)NC(C)(C)C)C(=O)c1ccc(N)cc1 +CC(NC(=O)NCc1ccco1)c1ccc(OC(F)F)cc1 +CC(=O)Nc1ccc(S(=O)(=O)Oc2c(C)nn(C)c2C)cc1 +COc1cc(C(=O)NC2CCCC2)ccc1OCC(C)C +Cc1ccnc(NC(=O)CSc2ccccc2)c1 +Cn1nnnc1SCC(=O)N1CC2(C)CC1CC(C)(C)C2 +COc1cc2ccccc2cc1C(=O)NCC(=O)NC(C)C +CC(c1cccs1)N(C)C(=O)Cc1n[nH]c2ccccc12 +O=C(Nc1nncs1)N1CCCC1Cc1ccccc1 +CCOC(=O)CCNC(=O)c1nc(C(C)C)ncc1Cl +CCOc1cccc(CNC(=O)Cc2nnc(-c3cnccn3)o2)c1 +OCc1ccc(CN(CCc2cccc(F)c2)C2CC2)o1 +Cc1ccc(CN2CC(C(=O)NC(C)C)C3(CCOCC3)C2)s1 +COCCNc1nc(NCCO)c2cnn(C)c2n1 +CCC(C(N)=O)N1C(=O)C(C)Nc2cc(C)c(C)cc21 +CC1(C)CCCN1C(=O)CCn1cnc2ccccc2c1=O +CCOC(=O)NC(NC(=O)OCC)c1cccnc1 +CC1CN(C(=O)CCn2c(=O)oc3ccccc32)c2ccccc21 +COC(=O)c1ccsc1-c1sccc1C(=O)OC +CC(CNC(=O)COc1cccc2c1CCC2=O)c1ccccc1 +COCc1cccc(C(=O)NCCCn2nc(C)cc2C)c1 +C1=C(c2nnc(-c3ccco3)o2)COc2ccccc21 +Cc1n[nH]c(C)c1C(=O)Nc1cc(F)c(F)cc1F +Cc1nnc(SCC(O)CN2CCOCC2)s1 +O=C(Nc1cccc(N2CCCS2(=O)=O)c1)N1CCCCCC1 +O=C(OC1CCCCC1)c1ccc2[nH]c(=O)[nH]c2c1 +CC1CCCC(C)N(C(=O)NCCCCn2ccccc2=O)C1 +CC(C)C(=O)N1CCC(C(=O)N2CCc3nocc3C2)CC1 +O=C(NC1CCN(C(=O)c2cc3ccoc3s2)C1)c1cccnc1 +OC1C2CC3CC1CC(CNc1ncccn1)(C3)C2 +Cc1noc(-c2ccc(C(=O)Nc3ccccc3C#N)cc2)n1 +Cc1ncc(Cl)c(C(=O)Nc2c(C)cccc2Cl)n1 +O=C(NC1CCCN(c2cccnc2)C1=O)c1c(F)cccc1Cl +CN(C)S(=O)(=O)N1CCCC1c1nnc2ccccn12 +CC1CN(Cc2ncccc2C(F)(F)F)C(C)(C)CO1 +O=c1ccn(-c2ccccc2)nc1-c1nc(-c2cccnc2)no1 +CS(=O)(=O)NC(Cn1cncn1)c1ccccc1 +Cc1nc(C)c(C(=O)NCC2(c3ccc(F)cc3F)CC2)s1 +O=S(=O)(c1ccc2c(c1)CCO2)N(Cc1ccncc1)C1CC1 +CCC(CC#N)NC1CCOc2ccc(OC)cc21 +COCC(=O)NC(Cc1ccc(F)cc1)C(C)C +Cc1ccc(OC(=O)CN(C)S(=O)(=O)c2ccc(C#N)cc2)cc1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(O)cn2)cc1 +Cc1ccc2ncc(C(=O)N(Cc3ccccc3)C(C)C)c(=O)n2c1 +COc1c(F)cc(NC(=O)C2CC(=O)N(C(C)C)C2)cc1F +Cc1nn(Cc2nnc(C3CC3)o2)c(=O)c(C#N)c1C +COc1ccc(OC)c(NC(=O)c2cc(NC(C)=O)ccc2F)c1 +Cc1c(C(=O)N2CCc3cc(F)ccc3C2)cnn1CCC(C)C +CCc1ncc(C(=O)NCc2ccc(-n3ccnc3C)cc2)cn1 +COC(=O)C1CCCC(=O)N1c1cc(C)cc(C)c1 +O=C(c1ccco1)N1CCc2c1cccc2C(F)(F)F +NC(=O)c1nc(COc2ccc3c(c2)NC(=O)CC3)no1 +Cc1ccc(=NS(=O)(=O)c2cc(Cl)c3c(c2)CC(C)O3)[nH]c1 +Cc1cc(C)n2nc(C(=O)NC(c3ccccc3)C3CC3)nc2n1 +Nc1ccc(S(=O)(=O)NCCC2CCCC2)c(Br)c1 +CC(C)CNC(=O)CN1CCN(c2ccccc2O)CC1 +CCC(NC(=O)c1ccc(S(N)(=O)=O)cc1)c1ccc(C)cc1 +CNC(=O)c1ccccc1OS(=O)(=O)c1cccs1 +O=C(NCc1cn(-c2ccccc2)nn1)NC(CO)c1ccccc1 +CC(C)NC(=O)c1ccc(Cl)cc1NC(=O)CCc1cccnc1 +O=C(NCc1ccsc1)NCC(O)c1ccsc1 +CC(C)(C)CCNS(=O)(=O)c1ccc2c(c1)CCO2 +CNC(=O)c1nnc2c(-c3ccccc3)ccnn12 +CC(C)Oc1ccc(NS(=O)(=O)CC(=O)N(C)C)cc1 +O=c1ccc(C(F)(F)F)cn1CCOc1ccc(F)cc1 +COCCOc1ncccc1C(=O)N(C)c1cccc(C#N)c1 +COC(=O)c1ccc(C(=O)N(C)Cc2cnn(C)c2)s1 +CC(C)OC(c1ccccc1O)C(O)c1ccccc1 +Cc1cc(C)n(-c2ccc(Cn3nc4ccccn4c3=O)cc2)n1 +CCOC(CC)C(=O)NCCc1nnc2n1CCCCC2 +CCOc1ncnc2c1CN(c1cnc3ccccc3n1)CC2 +CCCN(CCC(=O)N1CCNCC1)S(=O)(=O)c1ccccc1 +Cc1cc(NC(=O)CN2CCN(c3ccccc3F)C2=O)no1 +CC(NC(=O)c1ccc(F)cc1F)c1ccc(S(N)(=O)=O)cc1 +COc1cc2c(cc1OC)CN(C(=O)Cc1cccc(O)c1)CC2 +O=C(Cc1ccc2c(c1)CCCC2)N1CCC(O)C1 +CC(C)C1C(=O)NCCN1Cc1cc(O)ccc1Br +Cc1ccc(CC(=O)Nc2c(C)cc(C)nc2C)cc1 +O=C1C2C3CCN(c4ccncn4)C34C(=O)C14C=CN2c1ccncn1 +Cc1nn(C)c(C)c1CCn1cncc1-c1ccc2c(c1)CC(C)N2C +CC(C)(Cc1ccccc1)NC(=O)Cc1cccnc1 +CCn1nc(C)c(CCN(C)C(=O)Nc2ccccc2OC)c1C +CC(OC(=O)c1cccc(N2CCOC2=O)c1)c1ccccn1 +O=C(c1ccccc1)N1CCN(c2cc(-c3ccccc3)ncn2)CC1 +COc1cccc(CC(=O)NCC(O)c2cccn2C)c1 +N#Cc1cccc(NC(=O)NCCNS(=O)(=O)c2ccccc2)c1 +COc1ccc(NC(=O)Nc2cccc(C(C)=O)c2)cc1 +CCCN1C(=O)C2CCC1CN(C(=O)c1ccc[nH]1)C2 +CN(Cc1cscn1)S(=O)(=O)c1cc(Cl)ccc1N +O=C1CCC(C(=O)c2ccc(Br)cc2)O1 +CC(=O)N1CCc2ccc(S(N)(=O)=O)cc2C1 +CC(O)CN1CCN(C(=O)c2ccc(OCC(N)=O)cc2)CC1 +Cc1cc(Cl)ccc1NC(=O)Cn1cnc(C2CCC2)cc1=O +COc1cc(C)c(C(C)NC(=O)c2c(C)cc(C)[nH]c2=O)cc1OC +Cc1nc(C(=O)N2Cc3cncn3CC(COCC3CC3)C2)cs1 +Cc1nn(C)c2ncc(NC(=O)c3ccc4[nH]nnc4c3)cc12 +COc1cccc(Cn2c(=O)[nH]c3ccsc3c2=O)c1 +CCS(=O)(=O)Nc1ccnn1Cc1ccc(OC)cc1 +COc1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cn1 +Nc1cccc(-c2n[nH]c(Cc3cc(F)cc(F)c3)n2)c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)N1CCCC1CC(C)(C)C +COC(=O)c1ccc(Nc2ccc(OCC3CCCO3)cc2)nn1 +Cc1ccc2cnn(CCC(=O)NCc3c(C)nn(C)c3C)c2c1 +CC1(C)Cc2ccc(C(=O)NCC(C)(O)c3ccsc3)c(O)c2O1 +N#Cc1cnn(-c2ccc(NC(=O)C3(c4ccccc4)CC3)cc2)c1N +CC(C)NC(=O)c1ccc(NC(=O)c2cccs2)cc1 +COc1ccc(C2CC(=O)NCc3nc4ccccn4c32)cc1O +COc1ccc(CCNC(C)c2cccs2)cc1OC +CC(C)=CC1C(C(=O)N2CCCN(Cc3nccn3C)CC2)C1(C)C +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccn(C)n2)c1C +Cc1ccc(CCNC(=O)N2CCCN(C(=O)C3CC3)CC2)cn1 +Cc1nc(-c2ccc(C(F)(F)F)cc2)ncc1C(=O)NC1CC1 +CCOCC1CCCC12CN(Cc1cccnc1)CCO2 +COCC(=O)N1CCCC(CNC(=O)Cc2ccc(OC)cc2)C1 +Cc1ccccc1SCC(=O)NCc1cnn(-c2ccccc2)c1 +CNC(=O)C(C)NC(=O)c1ccc(Br)c(F)c1 +CCn1cc(NC(=O)c2cc(NC(C)=O)ccc2O)ccc1=O +CC1CCCC(C)N1C(=O)CNc1cccc(-c2nnnn2C)c1 +O=C(NCC(F)(F)F)c1coc(COc2ccccc2F)n1 +CCOC(=O)CNC(=O)c1sccc1-c1ccccc1 +Cn1c(CO)cnc1S(=O)(=O)Cc1coc(-c2cccs2)n1 +CC(Cn1cccn1)NC(=O)c1ccc(OC(C)C)nc1 +COCCOc1ccccc1C(=O)Nc1ccc(Cl)cn1 +Cn1ncc(C(=O)NCCc2nccs2)c1N +O=C(c1cccn1Cc1cccs1)N1CCCC1Cn1cccn1 +CCOC(=O)c1cn(CC(=O)OC)c2ccc(Cl)cc2c1=O +CC(C)Nc1nnc(SCc2cn3ccccc3n2)s1 +COc1cc(C#N)ccc1OC(=O)C(NC(C)=O)C(C)C +CC(C)(C)OC(=O)N1CCC(CSc2cccc(N)c2)CC1 +Cc1csc(C(C)NC(=O)c2ccncc2F)n1 +COc1ccc(Cl)cc1-c1cncc(C(N)=O)c1 +CCn1nnnc1NCc1ccccc1OCc1ccc(F)cc1 +Cc1n[nH]c(C)c1S(=O)(=O)NCC1CCCOC1 +O=C(NC1CCCCC1)c1nc2ccccc2c(=O)[nH]1 +N#Cc1c(N)nc2c(c1-c1ccc(F)cc1)CCC2 +CCn1c(C)nnc1SCc1nc(-c2ccc3c(c2)OCO3)no1 +Cc1noc(C2CC3OCCC3N(Cc3cc(C)c(C)o3)C2)n1 +CNC(=O)NCC(=O)NC(C)(C)c1ccc(Cl)cc1 +CC(Oc1cccc(Cl)c1)C(=O)N1CCC(CO)C1 +Cc1ccc(CN(C(=O)Cn2cnc(C3CCC3)cc2=O)C2CC2)o1 +Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Oc1ccccc1 +COc1ccccc1NCC(=O)NC1CCC(C)CC1 +Cc1cc(C(=O)NCC2CC2C)c2ccccc2n1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)OCC(=O)NC1CCCCC1 +NC(=O)CN(C(=O)c1cc(Br)c[nH]1)C1CCCC1 +CCN(Cc1noc(CC(C)C)n1)C(=O)c1cn2ccc(C)cc2n1 +COc1ccc(CN(C)C(=O)c2ccncc2F)cc1OC(F)F +CC1(C)C2OCCC2C1OC(=O)c1ccc(N2CCCC2)nc1 +COc1ccccc1CC(=O)NCC1(C(N)=O)CCOCC1 +COc1ccc2c(C)cc3nnc(SCCCO)n3c2c1 +Cc1ccc(CCNS(=O)(=O)c2ccc(C#N)cc2Cl)cn1 +Cc1ncsc1C(C)Nc1ccc2nccnc2c1 +Cn1cccc1C(=O)NCc1ccccc1CN1CCOCC1 +Cc1noc(COCC(=O)NC(C)(C)c2ccc(Cl)cc2)n1 +C=CCNc1nc(-c2ccc3c(c2)CCN3C(C)=O)c(C)s1 +COc1ccc(C(=O)OCC(=O)c2[nH]c(C)c(C(C)=O)c2C)cc1 +CC(C)COc1cccc(CNC(=O)NC(C)C2CCCO2)c1 +CNC(C)C1NCCc2cc(Cl)c(O)c(OC)c21 +CS(=O)(=O)c1nccn1Cc1nccn1Cc1ccccc1 +COc1ccc(OC)c(CNC(=O)Cc2c(C)noc2C)c1 +O=C1NCC(C(=O)N2CCCC2CCc2ccccc2)N1 +CC(C)NS(=O)(=O)c1cc(C(=O)N2CCOCC2)cs1 +Cc1c(C(=O)OC(C(N)=O)c2ccccc2)oc2ccc(F)cc12 +CC(C)NC(=O)Cc1cc(-c2cc3ccccc3o2)on1 +NC(=O)Cc1csc(NC(=O)C2CC2c2ccc(F)cc2)n1 +Cc1noc(COC(=O)c2cccc(NC(=O)c3cccs3)c2)n1 +COc1cccc2c(=O)n(Cc3ccccc3C#N)ccc12 +Cn1cc(C(=O)Nc2cccc3cn[nH]c23)c(-c2cccs2)n1 +COc1ccc(C(F)(F)c2nc(C(C)(C)OC)no2)cc1 +O=C(OCCNc1cccnn1)c1cccc(-n2cccn2)n1 +NC(=O)CC1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 +Cc1cccc2sc(NC(=O)c3ccn(C)n3)nc12 +CCc1ccc(OCC(=O)Nc2ccc(CC(=O)NC)cc2)cc1 +CS(=O)(=O)c1cnc(-c2ccncc2)nc1-c1cccc(F)c1 +COc1cccc(C(=O)NCCN2CCOCC2)c1O +Cn1cc(C(O)CNS(=O)(=O)Cc2ccc(F)c(Cl)c2)cn1 +O=C(CCCNC(=O)c1ccsc1)Nc1nc(-c2ccco2)n[nH]1 +CCCn1cc(-c2ccncc2)cc1C(=O)N1CCCC1 +COC(=O)CNC(=O)C1CCN(c2nc(C)c3ccccc3n2)CC1 +CCC(C)(C)C(=O)NCc1ccc(C#CCO)cc1 +O=C(Nc1ccccc1)NC1CCN(CC(F)(F)F)C1 +CC(C)(C)NC(=O)CNC(=O)C1CC1c1ccco1 +CC(C)(O)CCc1cccc(-c2nc(C3CCOC3)no2)c1 +Cc1cc(C(C)NC(=O)c2cc(N)c[nH]2)c(C)s1 +Cc1ccc(OCC(=O)N2CCC(C(N)=O)C2)cc1C +CC(C)S(=O)(=O)NCC#Cc1ccc(C(=O)N(C)C)cc1 +Nc1occ(-c2ccc(F)cc2)c1C(=O)c1ccccn1 +Cc1nccn1-c1ccc(C(C)NC(=O)C2C3CCCC32)cc1F +CC(C)Cn1c(N)c(-c2csc(C3CC3)n2)c(=O)n(C)c1=O +CSc1ccc(-c2csc(NC(=O)Cn3cnnn3)n2)cc1 +Clc1ccc(Cl)c2c1CCNC2c1nccs1 +CCCC(NC(=O)c1ccc(=O)[nH]c1)c1ccccc1 +CC(=O)c1[nH]c(C)c(C(=O)NCc2ccccc2-n2cncn2)c1C +O=C(C1CC(=O)N(C2CC2)C1)N1CCCN(c2ncccn2)CC1 +Cn1ccc2c(NC(=O)NC3CCC(O)CC3)cccc21 +C=C(C)CN1C(=O)C(C)(C)Oc2c(OC)cc(CO)cc21 +COCCN(C)C(=O)Nc1cc(OC)ccc1F +CCC(C)NC(=O)C1CC(=O)OC12CCCCC2 +Cc1nc(C(=O)N(Cc2ccsc2)CC2CCCO2)cs1 +CCN(CC)C(=O)c1ccc(-c2ccc(OC)c(CO)c2)cc1 +Cc1ccc(C)c(C(=O)CSc2nnc(-c3cccnc3)n2C)c1 +O=C(Nc1ccc(Oc2cnccn2)cc1)c1sccc1C1CC1 +CC(NC(=O)CCc1ccc(F)cc1)C(=O)N1CCOCC1 +COc1cccc(OCC(=O)NCC2CN3CCCCC3CO2)c1 +CCN(CC)C(=O)CNc1ccc2c3c(cccc13)CC2 +CNC(=O)c1cccc(OC(=O)CCNC(=O)c2ccco2)c1 +Cc1ccncc1NC(=O)NCC(=O)Nc1ccc(F)c(F)c1F +CCCCCn1cnc2c1c(=O)n(C)c(=O)n2CCCC +Cc1cccnc1NC(=O)c1cc(C)c(C)c(S(=O)(=O)N(C)C)c1 +CCOC(=O)C1C2c3ccccc3OC1(C)Nc1ncnn12 +CC1CCN(C(=O)c2cc(OCc3ccccc3)no2)CC1 +COc1ccc(NC(=O)c2cnn(C)c2N)c(OC)c1 +CC(NC(=O)c1ccncc1)c1nnc2n1CCC2 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cccn1C +CC(C)c1nccn1CCN1CCN(CC(N)=O)CC1 +CCCCC(=O)Nc1ccc(-n2ccnc2-c2ncc[nH]2)cc1C +COCC1CN(C(=O)c2ccnnc2)Cc2c1cnn2C +CC(=O)Nc1ccccc1OCC(=O)Nc1cccc(C#N)c1 +Cc1ccc2ncc(C(=O)NC3CCC(=O)N(C)C3)n2c1 +CCNC(=O)c1ccc(NC(=O)C(NC(C)=O)C(C)C)c(C)c1 +CC(=O)NCc1ccc(C(=O)NC(c2ccccc2)C(C)C)cc1 +O=C(Cc1ccc(Cl)cc1)NCCNC(=O)C1CC1 +Cc1noc(C)c1CC(=O)NCC#Cc1ccccc1C(F)(F)F +COc1ccc(OC)c(NC(=O)CCn2ccc3ccc(F)cc32)c1 +CN(Cc1nnc2n1CCC2)C(=O)C1CCCO1 +NC(=O)c1ccc(CN(Cc2cccnc2)CC2CCCO2)cc1 +O=C(Cc1ccc(-n2cccn2)cc1)NC1c2ccccc2CC1O +COC(=O)c1cc(Cn2cnc3cc(F)ccc3c2=O)c(C)s1 +CNS(=O)(=O)c1cccc(C(C)Nc2ccc(C)cc2)c1 +CC=Cc1ccc(OCC(=O)N(C)CC(F)(F)F)c(OC)c1 +Cc1ccc(CN(C(=O)c2ccc(-n3cnnc3)cc2)C2CC2)s1 +N#Cc1ccccc1NC(=O)c1cc(Cl)c2c(c1)OCO2 +O=C(COCC1CCCO1)Nc1cc(Cl)c(Cl)cn1 +CC(C1CC1)N(C)C(=O)c1ccc(Cn2ccccc2=O)o1 +COc1cccc(CN2CCOC(C)(C)C2)c1OC(F)F +O=C(CNC(=O)c1cccc2ccoc12)NCC1CCCCC1 +O=C(OCCN1CCOC1=O)c1sc2ccccc2c1Cl +Cc1nc(C(C)C)ncc1C(=O)N1CCC(CO)C(O)C1 +O=C1CCc2c1cnc1nc(Nc3ccc(F)cc3)[nH]c(=O)c21 +COc1ccc(C(=O)Nc2cc(F)c(F)cc2N)cc1 +COc1ncccc1NC(=O)NC1CCN(c2ncccn2)CC1 +COc1cccc(C2CCCN2C(=O)Cn2ccc(=O)[nH]c2=O)c1 +O=C(COc1nncc2ccccc12)Nc1ccccc1Cl +O=C(N1CCN(c2ccccc2O)CC1)C1(c2ccccc2)CCC1 +COc1ncccc1C(=O)NCC1CC(=O)N(C2CCCC2)C1 +COc1cc(CNC(=O)c2sccc2Br)ccn1 +Cc1c(-c2cn(Cc3ccccc3)cc2N)cnn1C +Cc1cccc(CNC(=O)c2nc3cccnc3n(C)c2=O)c1 +CC(C)N1CCOC2CN(C(=O)Cc3cccs3)CC21 +COCc1ccc(C(=O)Nc2ccc3nc(C)[nH]c3c2)o1 +COc1ccc(-c2nonc2NC(=O)COc2ccccc2F)cc1 +CN(C)S(=O)(=O)c1ccc(CN2CCCc3cccc(F)c32)o1 +CN1C(=O)C(O)N=C(c2ccccc2)c2ccccc21 +O=C(C(c1ccccc1)C(O)c1ccccc1)N1CCOCC1 +Cc1cc(C(=O)NC2CCN(C(=O)NC3CCCCC3)CC2)no1 +NC(=O)Nc1ccc(-c2csc(CC3CC3)n2)cc1 +Cc1ccoc1-c1nnc(CN2CCCC2c2c(C)nn(C)c2C)o1 +Cn1ccc(NC(=O)Cc2cccc3ccccc23)n1 +O=C(Cc1ccccc1)NCCC(=O)N1CCc2nocc2C1 +Cc1occc1CN(C)C(=O)NCCc1nnc2n1CCCCC2 +Cc1cccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3C)c1 +CN(C)c1ccc(NC(=O)N2CCNC(=O)C2)c(C(F)(F)F)c1 +CCC1CCCCC1NC(=O)NCc1ccco1 +CCC(C(=O)OC)n1cnc2c(nnn2-c2cccc(Cl)c2)c1=O +Nc1nc(N)nc(COC(=O)c2ccccc2Oc2ccccc2)n1 +CCC(CC)C(=O)Nc1c(C)nn(C)c1C(=O)OC +Cc1ccccc1CC1Oc2ccc(O)cc2N(CCO)C1=O +COc1ccc(O)c(C(=O)Nc2c(C)n[nH]c2C)c1 +CNC(=O)COC(=O)c1cc(-c2ccc(C)cc2)nc2ccccc12 +COc1ccccc1OC1CCN(CCOc2ccccc2)C1 +CC(NC(=O)CSc1nnc2n1CCCCC2)C(=O)N(C)C +CCc1ccccc1C(=O)Nc1ccc2c(c1)COC2 +Cc1ocnc1CNS(=O)(=O)Cc1cccc2cccnc12 +Cc1cc(C)n(-c2nc(C)c(C(=O)Nc3ccccc3)s2)n1 +COc1ccc2c(ccn2CCNC(=O)c2sc(C)nc2C)c1 +CCOc1ccc(-c2cc(C#N)nn2C)cc1OCC +O=C(Cc1ccc(N2CCNC2=O)cc1)NCC1=CCCCC1 +FC(F)(F)c1cc(-c2ccccc2)nc2nnnn12 +CN(C)c1ncccc1NC(=O)CNC(=O)NC1CC1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(C)c(Cl)c2)cc1 +COc1cc(C(=O)NCCc2cccs2)cc2c1OCCO2 +N#Cc1c[nH]c(C(=O)Nc2cccc(OCc3ccncc3)c2)c1 +N#Cc1ccc(-c2nc(-c3ccc(N4CCOCC4)cc3)no2)cc1 +COc1cccc2c1OCC(NC(=O)N(C)CCOCC1CC1)C2 +O=C1OCCC1Sc1nc(-c2ccccc2)c(-c2ccccc2)o1 +O=C(c1ccon1)N(Cc1ccccc1)CC(O)c1cccs1 +CCCCS(=O)(=O)N(CCC#N)c1ccccc1 +Cc1cc(C)nc(N2CCC(c3nccnc3C)CC2)n1 +CC(NC(=O)c1ccccc1Cl)C(=O)Nc1ccc(F)c(F)c1 +CCC(C)N(Cc1ccccc1)C(=O)c1nc2nccc(C)n2n1 +O=C(Nc1cccnc1)NC(CO)c1ccccc1 +COC(=O)c1sccc1NC(=O)c1ccccc1Br +Cn1nnnc1-c1cccc(NC(=O)c2cc(C(N)=O)cs2)c1 +CCOC(C)C(=O)Nc1cc(C(C)C)c(O)cc1C +O=C(NCC(O)c1ccccc1Cl)c1cccc(-n2cncn2)c1 +c1ccc(CCCn2ccnc2-c2ccccn2)cc1 +CCn1c(SCc2cc(C)no2)nc2ccccc2c1=O +O=C(COc1ccc2nc3n(c(=O)c2c1)CCC3)N(CCO)CCO +Cc1cc(NC(=O)CCc2cc(Cl)cs2)no1 +Cc1cccc(-c2noc(C3CCCN3C(=O)C3CC3)n2)c1 +Cc1cccc(CNC(=O)C2COc3ccccc3C2)c1 +Cc1cc(OCCn2cccc(OCC(N)=O)c2=O)ccc1N +COc1ccc(C(C)C)cc1C(O)Cn1cc(N)cn1 +CC(=O)c1ccc(C(=O)Nc2nc3c(s2)CCCC3)cc1 +Cc1cccc(N2CC(C(=O)NC(C)C)CC2=O)c1C +CCOC(=O)CCC(=O)c1ccc(F)c(Cl)c1 +CC(C)c1csc(C(=O)N(Cc2cnn(C)c2)C(C)C)n1 +COC(=O)NCCC(=O)N(Cc1c(F)cccc1Cl)C1CC1 +Cc1nccc(-c2cccc(NC(=O)C3CCCC3)c2)n1 +CC(=O)c1ccccc1NC(=O)C1CCN(C(=O)C(C)C)CC1 +CC(C)(C)NC(=O)NC1CCN(C(=O)c2cnc3ccoc3c2)C1 +CC(C(=O)NC1CC1)N1CCN(C(=O)c2ccc3cc[nH]c3c2)CC1 +CCOCCC(=O)Nc1cccc(S(=O)(=O)N(C)C)c1 +Cc1noc(C)c1CC(=O)NCc1cc(-c2ccccc2)on1 +Cc1cccn(Cc2ccc(F)c3cccnc23)c1=O +CCOC(=O)c1c(C)[nH]c(C(=O)NCc2ccncc2)c1C +Cc1cc(C(=O)N2CCCC(c3ccn[nH]3)C2)c(C)n1CC1CC1 +Cc1cc(NC(=O)CNc2cccc(-c3nc(C)cs3)c2)on1 +Cc1nc(CN(C)Cc2cccnc2)n(-c2cccc(Cl)c2F)n1 +CCCc1cc(C(=O)N2CCn3cccc3C2c2cccnc2)[nH]n1 +CCCc1nc2sc(=Cc3cccs3)c(=O)n2n1 +CCN(C(=O)c1ccc2c(c1)CCC(=O)N2C)c1ccc(C#N)cc1 +CCN(CC)S(=O)(=O)N(Cc1ccncc1)C1CC1 +COCCN(C)S(=O)(=O)c1cc(F)ccc1F +COc1cccc(OC)c1OC1(CO)CCCCC1 +O=C(NC1(c2ccc(F)cc2F)CCCC1)c1ccncc1 +COC(=O)c1c(C)nn2c1ncc1c(=O)n(C3CCCC3)ccc12 +O=C(CC1(O)CCCC1)Nc1cc(Cl)ccc1O +O=C(C1CC1)N1CCCC1Cn1nnc2ccccc2c1=O +CSc1nnc2c(n1)OC(c1ccc(O)cc1)Nc1ccccc1-2 +Cc1ccc2sc(NCc3ccc(C)nc3)nc2c1 +Cc1nc2ccccc2n1CC(=O)N1CCc2sccc2C1 +CC(=O)NCC1CCCN(C(=O)CCCCc2ccc(C)cc2)C1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(C)c(C)c1 +CC(=O)c1ccc(NC(=O)N2CCC(c3cnn(C)c3)CC2)cc1C +CCCS(=O)(=O)N1CCCC(C(=O)NCCc2ccccc2)C1 +Cc1noc(C(C)NC(=O)COc2ccc(F)cc2F)n1 +O=C(NCc1ccco1)Nc1ccc(-c2ccccc2)nn1 +O=C(CN1CCc2ccccc21)Nc1ccccc1O +Nc1ccc(C(=O)NCc2nc(CCc3ccccc3)n[nH]2)cc1 +O=C(Nc1cn[nH]c1)N1CCCC1c1cccs1 +C=CCn1c(SCc2ccccc2C)nnc1C1CC1 +Cc1ccc(SCc2noc(-c3ccccc3O)n2)nc1 +CN(C)C(=O)c1cc(NC(=O)c2ccccc2Cl)c(=O)n(C)c1 +Cc1cc(N2CC(C)OC(C)C2)n2nc(-c3nccn3C)cc2n1 +Cc1ccccc1S(=O)(=O)Nc1ccc(N)cc1Cl +CCn1cc(C(=O)Nc2ccc(OC)cc2C)c(C)n1 +CCOC(=O)c1c(NCc2ccco2)c2cccc(Cl)c2[nH]c1=O +CC(C)N(CCC#N)C(=O)Nc1cc(Cl)ccc1Cl +CC(C)CC(NC(=O)c1ccc(CNC(N)=O)cc1)c1ccccc1 +Cc1c(-c2ccncc2)n[nH]c1NC(=O)CCOC(C)C +O=C(NCCCCc1nccs1)Nc1ccc(F)cc1F +CC(C)C(C)(O)CNC(=O)Nc1ccccc1F +CCn1nc(C)c(NS(=O)(=O)c2c(C)nn(CC)c2C)c1C +Cc1nc(-c2ccncc2)ncc1C(C)NCc1cccnc1 +N#Cc1cccc(C(=O)N2CCc3ncnc(NC4CC4)c3CC2)c1 +Cn1cc(C(=O)NC2CC2c2ccccc2C(F)(F)F)ccc1=O +O=C(CC1C=CCC1)Nc1ccc(Oc2ncccn2)cc1 +c1cnc(N2CCC3C2CCN3c2ncccn2)nc1 +Cc1ncc(CNC(=O)NCCc2nc3ccccc3s2)s1 +CC(O)C1CCCN(CC2=NS(=O)(=O)c3ccccc3N2)C1 +COCC(C)NC(=O)c1ccccc1OCc1c(C)noc1C +CN(C)c1ncc2c(n1)CCCC2NC(=O)CCc1cnccn1 +CCN1CCN(S(=O)(=O)N2CCc3ccccc3C2)CC1 +CCOC(=O)c1cnc2ccc(-c3ccccc3)nn2c1=O +CC(C)(CO)NC(=O)COc1cccc2ccccc12 +CC(Sc1nnnn1C1CC1)C(=O)Nc1ccccc1C(C)C +CCn1cc(S(=O)(=O)Nc2cccc(Cl)c2)c(N)n1 +COc1ccc(NC(=O)C2CCCN(C(=O)OC(C)(C)C)C2)cn1 +Cc1cccc(NS(=O)(=O)c2ccc3c(c2)OCCCO3)c1C +CC(C)CN(Cc1nccn1Cc1cccc(F)c1)C(=O)C1CC1 +Cc1ccc(Br)c(NCc2cn3cccnc3n2)c1 +CCOc1ccc(CC(=O)N2CCC(O)CC2)cc1Cl +CCOC(=O)CC1CCCCN1C(=O)Nc1ccc(OC)cc1C +COc1ccc(-c2nn(CCO)c3c2C(=O)CCC3)cc1 +O=C(NCC1CC12CCCc1ccccc12)C1CCCc2[nH]ncc21 +CSc1ccc(C(=O)Nc2ccc3nc[nH]c(=O)c3c2)cn1 +CC(=O)c1ccc(NC(=O)NC2(c3nccs3)CCCC2)cc1C +CC(C(N)=O)N1CCn2nc(CCC(=O)N3CCOCC3)cc2C1 +CCOc1ccccc1OC(=O)COc1ccc(C)cc1 +C=CCn1c(SCC(=O)NC2CC2)nnc1-c1ccncc1 +Cc1nc(C(=O)N2CCCCC2)cc(N2CCC(O)CC2)n1 +Cc1cccc(CNC(=O)CCc2ccccc2N)c1 +NC(=O)c1ccsc1NC(=O)COC(=O)Cc1ccccc1F +COC(=O)C(C)CN(C)C(=O)Nc1ccccc1 +NC(=O)c1ccc(NC(=O)c2cnc(C3CCCO3)s2)c(F)c1 +O=C(c1cccc(Oc2cnccn2)c1)N1CCOCC1 +CCn1cc(NC(=O)C(C)Oc2ccccc2Br)cn1 +CS(=O)(=O)N(CC(=O)N1CCOCC1)c1ccc2c(c1)OCO2 +Cc1ccc(NS(=O)(=O)c2ccc(N3CCOC3=O)cc2)cc1C +O=C(NCC(=O)N1CCCC1c1ccccc1)c1ccc(F)cc1 +Cc1nc(N2CCCOC(Cn3cccn3)C2)c2sccc2n1 +O=C(NC1(C(=O)NCC2CC2)CCCC1)C1Cc2cc(F)ccc2O1 +N#Cc1ncn(CC(O)c2ccc(C(F)(F)F)cc2)n1 +Cc1ccc(NC(=O)c2ccccc2O)c(OCC(=O)N(C)C)c1 +Nn1c(SCc2ccc(F)cc2Cl)nnc1-c1ccco1 +Cc1cc(NC(=O)NCCOC2CCCCC2C)no1 +Cc1nccn1-c1ccc(C(C)NC(=O)NCc2cnn(C)c2)cc1 +CNC(=O)CC(C#N)c1cccc(Br)c1 +O=C(COC(=O)c1ccccn1)NCc1ccc(Cl)cc1Cl +COc1ccc(-n2ncc3c(N(CCO)CCO)ncnc32)cc1 +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)CCC(=O)N3)s1 +COc1ccc(OC)c(S(=O)(=O)Nc2ccccc2)c1 +Cc1ccc(S(=O)(=O)NC(C)C2CCCO2)c2cccnc12 +NS(=O)(=O)c1ccc(NC(=O)CCn2cc(Cl)cn2)cc1 +COc1cccc(C(=O)NC(C)c2nc3ccccc3[nH]2)c1O +Cc1ccc(C(=O)NCC(=O)NCC(=O)NC(C)C)cc1 +Cc1cccc(NC(=O)CN(C)S(=O)(=O)c2cccs2)n1 +COc1ccc(C=Cc2nc3ccccc3c(=O)[nH]2)cc1O +CCOC(=O)c1cc2c(Br)cc(OC)c(OC)c2[nH]1 +Cn1cnc(CNC(=O)c2cccc3c2ccn3C)n1 +Cc1ccc(N2CCOC3CN(CC4CC4)CC32)nn1 +CCCC(=O)Nc1cccc(S(=O)(=O)N(C)C)c1 +CCNc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccc(Cl)cc1 +COCCN(C)C(=O)Nc1ccccc1C(=O)N(C)C +Fc1ccc(CNc2ncnc3ccc(F)cc23)cc1 +Cn1ccc(C(=O)N2CCCC3(CC(Oc4cccnc4)CO3)C2)n1 +CC(C)(C)CCOC(=O)CCn1ncc(=O)c2ccccc21 +O=C(CN1C(=O)COc2ccccc21)N=c1[nH]nc2ccccn12 +Cc1cnn(-c2ccc(C(=O)Nc3cccc(-c4cn[nH]c4)c3)cc2)c1 +COCCOc1c(Cl)cc(NC(=O)c2cccnc2)cc1Cl +COc1ccccc1C(C#N)CC(=O)Nc1ccccc1C#N +CCc1cc(C(O)Cc2ccccc2)cc2c1NC(=O)CC2 +COC(=O)Nc1ccc2c(c1)CN(C(=O)c1cccs1)CC2 +COc1ccccc1CN(C(=O)CNC(=O)c1ccccc1)C1CC1 +O=C(c1cccnc1)N1C2CCC1CC(c1ccc(F)cc1)C2 +COC(=O)c1cnc(-c2ccccn2)nc1C(F)(F)F +COC(=O)c1cc(C2CC2)nc2c1c(C)nn2CCC#N +O=c1ccc(C2NCCc3c(Cl)cc(F)cc32)c[nH]1 +COc1c(C)c(OCC=C(C)CO)cc(CO)c1CO +O=C(Cn1ccccc1=O)NCC1CN(Cc2ccccc2)CCO1 +CCn1cc(NC(=O)NCC(O)C(F)(F)F)cn1 +Cc1cccc(CN2C(=O)c3ccccc3S2(=O)=O)c1 +COC(=O)C1c2ccsc2CCN1C(=O)CN(C)S(C)(=O)=O +Cc1cccc(CNC(=O)N(C2CC2)C(C)c2ccco2)n1 +CCCC(=O)N1CCCCC1C(=O)N(Cc1ccccc1)C1CC1 +Cc1ccc(NC(=O)C2CCN(c3ccc4nncn4n3)CC2)nc1 +CC(=O)N1CCCc2cc(NC(=O)COc3ccccc3C)ccc21 +O=C(NCCSc1ccccc1)c1ccccc1-n1cccn1 +CCOC(=O)c1c(N)c(C(N)=O)nn1-c1ccccc1 +CC(Cc1ccc2c(c1)CCN2)N1CCN(c2ncccn2)CC1 +Cc1ccsc1CNC(=O)CN1CC(C)OCC1C +Cc1ccc(CC(=O)Nc2cccc(C(=O)N3CCCC3)c2)cn1 +COC(=O)CN(C)c1nccc2c(N)cc(F)cc12 +CC1CCCN(S(=O)(=O)N2CC=C(c3ccccc3)CC2)C1 +O=C(Nc1cccc(C(=O)Nc2ccncc2)c1)NC1CC1 +COc1cc(C#N)ccc1OC(=O)Cc1ccc(Cl)cc1 +O=C(Nc1cccc(N2CCCC2=O)c1)c1cccc(-n2cccn2)n1 +CC(=O)NCC1CCN(C(=O)C(c2ccccc2)n2cccn2)CC1 +COc1ccc(OC)c(C(O)CNc2ccccc2C#N)c1 +COC1C2CCC1N(Cc1ccc3ccccc3n1)CCO2 +CC(CO)NC(=O)c1nn(Cc2ccccc2)c(=O)c2ccccc12 +COc1ccc(F)cc1C(=O)NCC(C)c1ccncc1 +Cc1ccc(S(=O)(=O)NC2CCCCC2)c2c1NCCC2 +Cc1noc(CCC(=O)Oc2cccc(C)c2C)n1 +O=C(NCCCOc1ccc(F)cc1)NCC1CCC1 +Cc1ccc(S(=O)(=O)N2CCC(OCC(C)C)CC2)cc1C +Cc1n[nH]c(-c2ccccc2NC(=O)c2cn[nH]n2)n1 +Cc1ccc2c(c1)SCC(=O)N2CCn1cnnc1C +O=C(CN1CCN(CC2=CCCOC2)CC1)N1CCc2ccccc21 +CN(CC1Cc2ccccc2CN1C)C(=O)c1cnn2ccccc12 +COc1ccc(OC)c(NC(=O)Cc2c(C)nc(C)[nH]c2=O)c1 +CCC1(C)Oc2ccc(NC(=O)CCn3cccn3)cc2O1 +Cc1cccc(CN(C(=O)c2ccc(N3CCNC3=O)cc2)C2CC2)c1 +Cc1ccc(NC(=O)CCOC(C)C)c2[nH]ncc12 +CC(C)(C)NC(=O)c1ccc(NC(=O)C2CC2)cc1 +Cc1cc(Br)ccc1-n1cc(C#N)cn1 +Cc1ccc(=O)n(CC(=O)N2CCCC2c2noc(C3CC3)n2)n1 +COc1ccc(NC(=O)N(C)Cc2ccncc2)cc1 +O=C(Cc1ccccc1O)Nc1cccc(-n2cccn2)c1 +CN(C(=O)Cn1ncc(Cl)c(Cl)c1=O)C1CCCCC1 +NC(=O)C(c1ccccc1)N1CCN(C(=O)c2ccc[nH]2)CC1 +Cc1cc(NC(=O)c2cc(C3CC3)nc3c2cnn3C)on1 +CCNC(=O)CN(CC)C(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +Cc1nc2ncnn2c(C)c1CC(=O)NCCc1c[nH]c2ccccc12 +NC(=O)C1CCCN(C(=O)CCn2cnc3sccc3c2=O)C1 +NC(=O)Nc1nnc(-c2ccc(Cl)cc2)s1 +COc1ccc2c(ccn2CC(=O)N(CC(N)=O)C2CCCC2)c1 +O=C(OCc1ccccc1)N1CCC(CCCO)CC1 +CCC(=O)Nc1ccc(OCC(=O)N2CCC(=O)NCC2C)cc1 +Cc1ccc(NC(=O)CN2CCN(C(=O)C3CC3)CC2)cc1 +O=C1CCCc2[nH]c(=O)c(C(=O)Nn3cnnc3)cc21 +CCC(=O)N1CCc2[nH]cnc2C12CCN(c1cc(N)ncn1)CC2 +Cc1cc(=O)c(C(=O)NCC(=O)NC(C)C)nn1-c1ccccc1F +Cc1cc(C)n(-c2ccc(NCCc3nc(C)no3)nn2)n1 +Cc1ccc(C(N)C(=O)NCCC(C)C)cc1F +CCn1ncnc1C1CC(=O)NCc2nc(N3CCCC3)sc21 +CCC(CC#N)NC(=O)Nc1cccc(NC(=O)c2ccccc2)c1 +Cn1cccc1CNc1ccc2c(c1)CCC(=O)N2 +COc1cc(CO)c(OCc2cc(F)ccc2F)c(CO)c1 +N#CC(C(=O)CCC(=O)c1cccs1)c1nnc2n1CCCCC2 +COCCN(CC(C)C)C(=O)Nc1cc(F)ccc1OC +CCCC(=O)N1CCN(c2c(Cl)cccc2-n2cnnc2)CC1 +CS(=O)(=O)NC1C(=O)OC(C(O)CO)C1=O +CCCCS(=O)(=O)NCC(=O)Nc1cc(C)nn1C +Cc1cc(C)cc(NC(=O)COC(=O)c2ccccn2)c1 +COc1cc(CNC(=O)Cn2ncc(=O)c3ccccc32)ccn1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)NCc2cscn2)c1 +CCN(CC)C(=O)CNC(c1ccccc1)C(C)C +Cc1cc(NC(=O)CNc2ccc(C)c(Br)c2)on1 +Cc1cc(-c2csc(NCc3ccccc3)n2)c(C)o1 +C=CCNS(=O)(=O)c1ccc(C(=O)N2CCCC(CC)C2)cc1 +COC(=O)CC(c1ccc(OC)cc1OC)c1c(O)n[nH]c1C +Cc1cnn(CC2CCCN2C(=O)c2csc(-c3ccco3)n2)c1 +N#Cc1cccc(OCCCCC(=O)N2CCOCC2C2CC2)c1 +CCC1CCC(CNC(=O)c2ccnc(N)c2)CC1 +O=C(Nc1cnn(-c2ncccn2)c1)c1c(F)cccc1Cl +CC(=O)c1cc(-c2ccccc2Br)[nH]n1 +Cc1noc2ncc(S(=O)(=O)Oc3ccc(F)c(F)c3)cc12 +CCN(Cc1cnn(C)c1)C(=O)C1CCOc2ccccc21 +Cc1nc(C)c(CNS(=O)(=O)c2cccc(F)c2C#N)s1 +CC1CCCC1NC(=O)N1CCOCC1C1CC1 +COc1ccc(NC(=O)c2cnc(N3CCC(C)CC3)nc2C)cc1 +CCCCOc1ccc(C(=O)NCc2ccco2)cc1 +Fc1ccc(COc2ccccc2-c2ccnc3ncnn23)cc1 +O=C(Nc1cccnc1)C1CNCc2cccc(Cl)c21 +O=C(NCCC(=O)N1CCN(c2ccccc2)CC1)c1ccccn1 +CC(C)c1cc(C(=O)NC(C)c2nc(-c3ccccn3)no2)no1 +Cc1nn(C)cc1C(=O)Nc1ccn(Cc2ccccc2Cl)n1 +CC(=O)Nc1cccc(NC(=O)NCC2(c3ccccc3)CC2)c1C +Cc1cn(C)nc1C(=O)Nc1nnc(-c2cc(C)n(C)n2)o1 +Cc1nnnn1-c1ccccc1C(=O)NCCc1ccccn1 +N#Cc1cnn(-c2ccc(Oc3ccccc3)cc2)c1 +Cc1nn(C(C)(C)C)c2nc(C(C)C)cc(C(=O)Nc3nc[nH]n3)c12 +Cn1cc(S(=O)(=O)N2CCCN(c3ncccc3C#N)CC2)cn1 +Cc1ccc(Nc2c(C(=O)N3CCCC3)cnc3c2c(C)nn3C)cc1 +N#Cc1ccccc1OCn1nnc2ccccc21 +Cc1noc(C(C)C)c1C(=O)NCc1cccc(C(F)(F)F)c1 +COc1ccccc1NC(=O)NCCC(O)C(C)(C)C +COc1cccc(NCC(=O)NC2CCOCC2)c1 +COCCN1CCN(C(=O)c2oncc2C)CC1=O +Cc1cnc(NC(=O)C(C)Oc2cccc(Br)c2)s1 +NC(=O)c1cccc(S(=O)(=O)NC(C2CC2)C2CC2)c1 +Cc1ccc(NC(=O)COC(=O)c2ccoc2)cc1F +CN(C)C(=O)c1ccc(Cl)c(Br)c1 +O=C(NCC1CCCOC1)c1cccc(Br)c1 +CC(CC#N)N(C)Cc1cc(C(F)(F)F)ccc1Cl +CCCC(=O)c1ccc(OCC(=O)NC)c(N)c1 +Cc1nn(C)cc1CCC(=O)N1CC(C)(C)Sc2ccccc21 +CC(NC(=O)Cn1nc2n(c1=O)CCCCC2)c1ccccc1 +O=C(Nc1nc[nH]n1)c1occc1-c1ccccc1 +CC(C)NC(=O)N1CCN(c2ccc(F)cc2)CC1 +CCN(CC(C)C#N)C(=O)CNc1cc(F)ccc1C +CC1CCN(S(=O)(=O)N(C)Cc2c(F)cccc2Cl)CC1 +COc1ccccc1C(O)c1cc(C)c2c(c1)CCC(=O)N2 +COC(=O)c1cccc(OCc2csc(-c3cnn(C)c3)n2)c1 +COc1cc(C)ccc1OC(=O)c1cc2cnn(C(C)C)c2nc1C +Cc1csc(SCC(=O)Nc2ccccc2Br)n1 +CCCNC(=O)n1ccc(C(=O)Nc2ccccc2)n1 +Cc1cc(C(=O)NCC(O)(c2ccccc2)C(F)(F)F)no1 +CN(C)C(=O)N1CCC(C(=O)NCc2ccoc2)CC1 +O=C(Nc1ccccc1CO)c1cccc(Cl)c1 +Cc1cccc(-c2cc(C(=O)NCc3ccco3)no2)c1 +Cc1cn2c(CN(C)C(=O)C(C)C3CC3)c(C)nc2s1 +COc1ccccc1C(C)Cc1nc(-c2ccncc2)no1 +c1ccc(-c2nnnn2-c2cnc3ccccc3c2)cc1 +COCC(O)CN(C)S(=O)(=O)N1CCC(C)CC1 +CC1Oc2ccccc2N(CC(=O)N(C)c2ccc(F)cc2)C1=O +COCC(C)N(C)C(=O)c1ccc2c(c1)NC(=O)C(C)S2 +COc1cc(CO)ccc1OCc1ccc(Br)cc1 +CCOC(C)C(=O)Nc1cccc(N2CCCS2(=O)=O)c1 +O=C(NCc1ccnc(-n2ccnc2)c1)c1cccs1 +Cc1cc(C2CCC2)nc(N(C)Cc2cc(-c3ccccn3)no2)n1 +CC1c2cccn2CCN1C(=O)c1cc2ccccc2o1 +COc1ccc(CN(C)C(=O)COc2cccc(Cl)c2)cc1 +Cc1ccc(S(=O)(=O)NCc2ncoc2C)cc1Cl +CNS(=O)(=O)c1ccc(NCc2nc(C)cs2)cc1 +COc1ccccc1NC(=O)C1CC(=O)OC12CCCC2 +O=C1CCOc2ccc(S(=O)(=O)NCCCO)cc2N1 +NC(=O)c1cnc2n1CCN(C(=O)c1coc3c1C(=O)CCC3)C2 +O=S(=O)(N=c1[nH]c(C2CC2)cs1)c1ccc2c(c1)OCCO2 +COC(=O)c1cnc(N(C)C(=O)c2cc(OC)ccc2OC)s1 +Cc1cc(C(=O)NCC2CCCO2)c2ccccc2n1 +COc1ccc(CN(C(=O)Cc2c[nH]c3ccccc23)C2CC2)cc1 +Cc1c(Cl)cnn1C(C)C(=O)NCCCN1CCCC1=O +CCN(CCC(O)c1ccc(OC)c(N)c1)c1ccccc1 +COc1ccnc(NC(=O)CCNC(=O)Cc2ccccc2)c1 +Cc1cc(C(=O)N(C)Cc2cnc3ccccc3n2)no1 +O=C(Nc1ccc(Cl)cn1)C1CCCN(Cc2cncs2)C1 +Cc1cccc2c1CCN(C(=O)c1ccco1)C2C +Cn1cc(C(=O)NC(c2ccccc2)C2CCCC2)ccc1=O +COC(=O)c1cccc(C(=O)Nc2ccccc2C(=O)OC)c1 +O=C(NCC(O)CN1CCOCC1)C1CCCc2sccc21 +CCc1cc(C(=O)NCc2cccnc2)nc2cc(-c3ccco3)nn12 +CCC(OC(=O)c1cccc(N)c1)C(=O)Nc1ccccc1 +COc1cc(C(=O)NCC(=O)NC(C)(C)C)ccc1OC(F)F +Cc1noc(CCCC(=O)Nc2cccc3ccccc23)n1 +COc1cc(NC(=O)c2cccnc2SC)cc(OC)c1 +Cn1cc(C(C)(O)CNC(=O)Nc2ccccc2C(F)(F)F)cn1 +CC(C)(C)OC(=O)C(N)c1ccc(Br)cn1 +CCOCCn1c(=NC(=O)c2ccn(C)n2)sc2ccccc21 +Cc1nn(C)c(C)c1C1CCCN1C(=O)C(C)Cn1cccn1 +CCc1nc2ccccc2n1CC(O)COc1cccc(C(C)=O)c1 +C1CCC(Nc2nc3nonc3nc2N2CCCC2)CC1 +CCC(CC)N(CCc1ccccc1)C(=O)c1cnc(C)[nH]c1=O +Nc1ccc(NC(=O)Cc2cccs2)cc1F +Cn1cc(C(=O)NCc2ccncc2)c(=O)c2ccccc21 +O=S(=O)(c1ccc2ocnc2c1)c1ccc2ocnc2c1 +Cc1cc2c(NCCC(=O)NCc3cccnc3)ncnc2s1 +C#CCNC(=O)CNC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +COc1ccc(C(=O)N2CCCC2c2nc(C3CC3)no2)c(OC)c1 +CC(O)CN1CCN(C(=O)c2cn(-c3ccccc3Cl)nn2)CC1 +Cc1cccc(NC(=O)COC(=O)c2cc(C)oc2C)c1 +COc1ccc(Cl)cc1CNc1c(C)n[nH]c1C +CCC1CCN(C(=O)c2cnc3ccc(C)cn23)C1 +C=C(C)COc1ccc(C(O)CN2CC(C)OC(C)C2)cc1 +C#CCNC(=O)NC1CCN(C(=O)C(CC)CC)CC1 +COc1cccc(-n2nnnc2-c2ccc(C)c(N)c2)c1 +COc1cc(C2NC(=O)c3c(C)cccc3N2)cc(OC)c1OC 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+COC(=O)CCn1cnc2ccc(Cl)cc2c1=O +Cc1ccc(NC(=O)Nc2ccc(-c3noc(C4CCC4)n3)cc2)nc1 +Cc1[nH]ncc1CCCNC(=O)c1cc2ccccc2s1 +COc1ccc(CNC(=O)c2cnc(N(C)C)nc2N)cc1 +O=C(NCCNC(=O)c1ccco1)NCc1ccc(F)cc1 +Cc1nc(COCC23CCCC2CN(C(=O)N(C)C)C3)cs1 +CCOc1ccccc1S(=O)(=O)N1CC2CC1C(=O)O2 +CCN(CCC#N)S(=O)(=O)c1ccc(F)cc1F +CCc1nc2n(n1)CCCC2NC(=O)CC(CC)c1ccccc1 +CCC(NC(=O)N(C)Cc1csc(C)n1)C(C)C +Cc1nc2ccccn2c1C(=O)Nc1nc(-c2cccnc2)cs1 +CCNS(=O)(=O)c1ccc(C(=O)NC(C)c2ccncc2)cc1 +COC(=O)c1ccccc1Nc1ncnc(N2CCC(C)CC2)c1N +CCc1ccc(S(=O)(=O)NCc2cn[nH]c2)cc1 +CC(C)(C)OC(=O)N1CC(=O)OCC1Cc1ccccc1 +O=C(Cn1c(=O)cnc2ccccc21)NCC1Cc2ccccc2O1 +C=CCNC(=O)NCC#CCOc1ccc(C)nc1 +CNC(=O)c1cnn(C2CCN(S(=O)(=O)N3CCOCC3)C2)c1 +CCN(CC)S(=O)(=O)c1ccc(C)c(C(=O)N2CCCC2)c1 +CN(Cc1ccc(F)cc1)C(=O)CNc1c(F)cc(F)cc1F +CC(OC(=O)CCc1c[nH]c2ccccc12)C(=O)N1CCCC1 +O=S(=O)(c1cn[nH]c1)N1CCC(Cc2cnc3[nH]ccc3c2)C1 +Cc1nn2c(CNC(=O)c3nn(C)c4ccccc34)c(C)nc2s1 +CC(NC(N)=O)C(=O)N1CCN(C(=O)CC2CCCCC2)CC1 +COc1cc(OC)cc(C(=O)NC2CCN(C)C2=O)c1 +CCC(C)C(NC(=O)Nc1cccc(NC(C)=O)c1)C(=O)OC +Cc1cc(C)n(-c2nc3c(c(=O)n(C)c(=O)n3C)n2CC(C)C)n1 +O=C(Cc1cccnc1)NCCCCC1CCCC1 +Cc1cc(CNC(=O)CCc2c(C)nc3cc(O)nn3c2C)no1 +O=C(c1cc2c([nH]c1=O)CCCC2)N1CCCSc2ccccc21 +Cn1c2ccc(N)cc2n2c(Cc3ccccc3)nnc12 +CCc1ccc(OC)c(COC(=O)C(C)CC#N)c1 +COc1ccccc1-c1nc2c(s1)CC(=O)CC2 +CCN1CC(C(=O)NCCSc2nncn2C)CC1=O +COc1csc(C(=O)NC2(C)Cc3ccccc3C2)c1 +Cc1ccc(-n2nnnc2SCC(=O)NC(C)C)c(C)c1 +O=C(Cc1csc2ccccc12)NCc1ccc2c(c1)OCO2 +O=C(Nc1ccc(F)c(F)c1F)c1cc(Cl)c2c(c1)OCCO2 +CC(C)(C)C(=O)CNC(=O)COc1ccc2ccccc2c1 +COCCNc1nc(-c2cccnc2)nc2sc(C)c(C)c12 +O=C(Nc1ccc2c(c1)OCCO2)c1ccccc1NC(=O)C1CC1 +N#CC(C(=O)C1CCCCO1)c1ccccc1Cl +CCOC1CCN(c2ccc(S(N)(=O)=O)cc2C(=O)OC)CC1 +CC(=O)Nc1nc(C)c(-c2sccc2C)s1 +Cc1ccc(S(=O)(=O)NC(C)(C)C)cc1C(=O)Nc1cccnc1 +Cc1cc(C(=O)CSc2ccccc2Cl)c(C)[nH]1 +COc1cc2[nH]c3c(=O)n(CC4CCCO4)cnc3c2cc1OC +COCc1ccccc1C(=O)NCc1nncn1C(C)C +Cc1n[nH]c(C)c1S(=O)(=O)N1CCN(CCO)CC1 +COC(=O)C1CCN(C(=O)C2CCCOC2)CC1 +Cc1cccc(C(=O)NC(C)C(=O)NCc2cccnc2)c1 +CC(C)NC(=O)c1ccc(F)c(S(=O)(=O)NC2CC2)c1 +Cc1ccc(CN2CC(Oc3cccnc3)C3OCCCC32)s1 +CCc1nc(CC(=O)N2CC(c3ccccc3C)CC2C)cs1 +CCN(Cc1ccccc1C)C(=O)Cn1cnnn1 +CCNC(=O)N1CCN(C(C)c2nc(-c3cccs3)no2)CC1 +Cc1nc(SCC(C)C)n(CC2CCCO2)c1C +CCc1ccc(C(C)NC(=O)Nc2ccc(OCC(N)=O)cc2)cc1 +CC(C)C(=O)Nc1nc(CC(=O)N(C)CCC(F)(F)F)cs1 +O=C(Nc1ccc[nH]c1=O)C1(c2ccc3c(c2)OCCO3)CCCC1 +Cn1cc(C(=O)Nc2ccccc2O)c(-c2ccc(F)cc2F)n1 +O=C(Nc1ccccc1O)c1ccnc(OC2CCC2)c1 +COC(=O)c1cccc(CC(=O)Nc2cc(C)nc(C(C)C)n2)c1 +Cn1c(N)nnc1SCc1ccc2c(c1)CCC2 +CC(C)NC(=O)COc1cc2c(cc1CO)OCO2 +Cc1csc(NC(=O)Cn2nc(-c3ccccc3F)ccc2=O)n1 +COC(=O)c1ccc(NC(=O)NCC2COCCO2)c(Cl)c1 +CC(C)COC(C)c1noc(CSc2cccc(C#N)c2)n1 +O=C1c2ccccc2S(=O)(=O)c2cc(C(=O)N3CCCC3)ccc21 +CCc1cc(CNC(=O)Nc2ccc(C(=O)NC(C)C)cc2C)on1 +Cc1ccc(Cl)c(OC(=O)CSc2nnnn2C2CC2)c1 +CC(=O)Nc1ccc(Nc2ncnc3sc4c(c23)CCC4)cc1 +COC(=O)CCN(C)C(=O)CSc1ccc(Cl)cc1 +CC(O)CC(C)(C)CNC(=O)NC1CCCN(c2ccccc2)C1 +CCOC(=O)CNC(=O)Nc1c(C)nn(Cc2ccc(C)cc2)c1C +CC(CO)NC(=O)c1cc(F)ccc1Br +CN(c1ccc2nccnc2n1)C1CCN(c2ccccc2)C1=O +Nc1ccc(Cl)c2c(C(=O)NCc3ccncc3)nccc12 +O=C(NCc1nnc2n1CCC2)Nc1ccc(F)c(-n2cccc2)c1 +O=C(NC1CC1)C1CCCN1C(=O)C1CC1(Cl)Cl +Cc1ccc(NC(=O)NCC2CN(CC(C)C)CCO2)cc1 +Cc1cc(C)n(CCNC(=O)C2CC(=O)N(C3CC3)C2)n1 +N#Cc1c(N)nc2c(c1-c1cccc3c1OC(F)(F)O3)CNCC2 +CC(=O)Nc1cc(C(=O)NCC(C)C)nn1-c1ccccc1 +O=C(Cc1cnc(-n2cccc2)s1)Nc1ccc2c(c1)OCO2 +CCC(C(=O)OC)N1C(=O)C(C)(C)Oc2ccc(C(C)=O)cc21 +CCOc1ccc(NC(=O)C23CCC(C2)C(C)(C)C3=O)cc1 +COCCCNc1nc(-c2cccc(OC)c2)no1 +Cc1ccc(CN(C)Cc2nc(COc3ccccc3)no2)o1 +N#CCCN(CCN1CCOCC1)C(=O)c1ccc2ccccc2c1 +CC1CCCC(CNC(=O)CCNC(=O)c2ccc(F)cc2F)C1 +NC(=O)COc1ccc(CNC(=O)CN2CCc3ccccc32)cc1 +Cc1cccc(C(C)C)c1NC(=O)C1CCN(C(=O)C2CC2)CC1 +COc1cc(S(=O)(=O)N2CCCC(C)C2)ccc1Cl +CC(=O)OCc1c(C)cc(C)c(COC(C)=O)c1C +Cc1cccc(C2(C(=O)N3CCn4c(C)nnc4C3)CCCCC2)c1 +Cc1ccc(C)c(NC(=O)C(C)Oc2ccccc2N)c1 +CC(C)n1nccc1NC(=O)c1ccc(-c2ccccc2F)o1 +CCc1nonc1NC(=O)c1ccnc(OC(C)CC)c1 +COC(=O)c1ccc(N2Cc3cc(Cl)ccc3OCC2=O)cc1 +C=CCNC(=O)N1CCCC(C(=O)NCCCC)C1 +c1ccc(CC2CCN(c3ncnc4n[nH]cc34)CC2)cc1 +CNC(=O)c1ccsc1NC(=O)COc1ccc(Cl)cc1 +CCNC(=O)CN(CC)C(=O)Cc1csc(N2CCCC2=O)n1 +O=C(NCc1ccc2c(c1)OCCO2)c1csnn1 +CCCC1(NC(=O)c2coc(COc3ccc4c(c3)OCO4)n2)CC1 +Cc1ccc(C(=O)C(C)Sc2nnc(C)o2)cc1 +O=C(NCCCOCC1CCCO1)c1cc2ccccc2o1 +CCOC(C)c1nc(CSc2nnc(N)n2C)cs1 +COCc1ccccc1NCc1nnc2n(C)c(=O)c3ccccc3n12 +Cc1nc2n(n1)CCN(C(=O)c1cc(-c3cccs3)[nH]n1)C2 +NC(=O)CN(C(=O)Cn1c(=O)[nH]c2ccccc21)C1CCCC1 +CC(C)Oc1ccc(C(=O)N(CCC(N)=O)c2ccc(F)cc2)cn1 +CCOC(=O)c1csc(NC(=O)c2ccc(-n3cccc3)cc2)n1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(Cl)c(N)c1 +COc1cc(C)c(-c2nc(CN(C)Cc3ccno3)c(C)o2)cc1C +CCC1(CO)CCCN(C(=O)CCc2ccccc2)C1 +CCn1nc(C)c(CN2CCN(c3cc(C)nc(C)n3)CC2)c1C +CC(C)NC(=O)NCC1(COc2cnccn2)CC(O)C(O)C1 +CCOc1ccccc1-n1c(C)c(C)c(C#N)c1N +CCn1cc(CN(C)C(=O)c2cc(C(F)(F)F)n(C)n2)cn1 +COCCn1nc(-c2cc(OC)ccc2OC)cc(N)c1=O +O=C(NCC1CC=CCC1)C1COc2ccccc2O1 +CNC(=O)c1ccc(CN(C)C(=O)CNC(=O)c2cccs2)cc1 +Cc1cc(CN(C)C(=O)c2cccnc2N2CCCCC2)no1 +Cc1ccc(N2CC(C(=O)n3ccnc3)CC2=O)cc1C +Nc1cc(C(=O)N2CCCCC2CCO)ccc1F +O=C(Nc1nc(-c2ccco2)c(-c2ccco2)s1)c1ccncc1 +CNC(=O)C(C)N1C(=O)c2ccccc2S1(=O)=O +Cn1c(=O)n(CC(=O)Nc2cccc(C(F)(F)F)c2)c2ccccc21 +Cc1cc(=O)n(CCN2CCOCC2)c(N2CCCCC2)n1 +Cc1csc(SCC(=O)c2ccc3c(c2)OCO3)n1 +O=C(NCc1ccccn1)Nc1cnn(-c2ccccc2)c1 +CCc1c(C)nc2ncnn2c1NCc1ccccc1OC +COc1ccc(OC)c(Nc2ncnc3[nH]c(C)nc23)c1 +NS(=O)(=O)c1cccc(S(=O)(=O)NCCCC2CCCC2)c1 +NC(=O)C1(CNC(=O)Nc2ccccc2Cl)CCOCC1 +Fc1ccc(-n2cnnc2-c2ccccc2)c(F)c1 +COC(=O)c1c2c(cc3c1CC1(Cc4ccccc4C1=O)C3)CCC2 +COC(=O)c1sccc1S(=O)(=O)Nc1cc(F)ccc1C +O=C(NCCCNC(=O)c1ccc(F)cc1F)c1cccc(O)c1 +COC(=O)C(NCC(F)(F)F)c1cc(C)sc1C +COC(=O)CCS(=O)(=O)NC1CCC(O)CC1 +CC(=O)NC(CC(=O)OC(C)c1ccccn1)c1ccc(Cl)cc1 +COC(=O)C(C)CN(C)C(=O)c1ccc(Br)cc1Cl +C#CCN1CCN(CC(=O)N2CCCC(NC(C)=O)C2)CC1 +CCc1nnc(N2CCN(c3cc(C)nc4ncnn34)CC2)o1 +COC(=O)c1cccc(CC(=O)Nc2cc(F)ccc2OC)c1 +COc1ccc2c(c1)cc(C(=O)NC1CCCOC1)n2C +CC(C)Cc1nc(C(=O)Nc2ccncc2)cs1 +N#CCCn1nc(-c2ccccc2)c2c1CCCC2CC#N +CCc1cc2c(=O)n(CCOc3ccccc3)cnc2s1 +COC1(C)CC(N(C)C(=O)c2cccnc2C)C1(C)C +COc1cc(CNC(=O)Nc2cccc(COC(C)C)c2)ccc1O +NC(=O)C1(NC(=O)c2cc(Cl)ccc2F)CCCCC1 +Cc1cc(C)n(CCCNC(=O)c2cnn(C)c2-n2cccc2)n1 +Cc1nn(C)c(C)c1C1CCCN1CC(O)CN1CCOCC1 +Cc1cccc(C)c1NC(=O)CCc1ccc2[nH]ccc2c1 +COC(=O)c1ccccc1NCC(=O)N1c2ccccc2CC1C +CCC(Sc1nccc(C)n1)C(=O)Nc1nccs1 +Cn1cc(C(N)=O)cc1C(=O)N1CC(C)(C)c2c(Cl)cccc21 +COCCCn1ccc2c(c(C)nc3nc(C)nn32)c1=O +Cc1cccc(CN(C(=O)C2CC=CC2)C2CC2)c1 +CCOc1ncccc1NC(=O)N(C)Cc1nnc2n1CCC2 +Cc1cnc2c(c1NCCCO)c(=O)n(C)c(=O)n2C +O=C(C1CC1)N1CCN(Cc2nnnn2-c2ccc(F)c(F)c2)CC1 +FC(F)(F)Oc1ccc(-c2nc(-c3ccncc3)no2)cc1 +NC(=O)c1csc(CN2CCOC(c3ccccc3Cl)C2)c1 +COc1ccc(OC)c(C(=O)NCC(O)c2ccc(F)cc2)c1 +Cc1ccncc1NC(=O)N1CCCC1c1cccc2c1OCCO2 +Nc1nc2c(c(=O)[nH]1)CCN(C(=O)c1n[nH]cc1Cl)C2 +Cc1cnc(CN2CCN(C(C)c3nc(C)no3)CC2)cn1 +CCOC(=O)C1C(=O)NCC1c1cc(OC)c2c(c1OC)OCO2 +CCOC(=O)C(N)Cc1nnc2sc3ccccc3n12 +Cc1ccc2ncc(C(=O)N(C)CCCNC(=O)OC(C)(C)C)n2c1 +CCNC(=O)c1cccc(NC(=O)C2CCC(=O)N2)c1 +COC(=O)c1ccc(S(=O)(=O)NCCC(=O)N(C)C)c(Cl)c1 +CC(C)(CNC(=O)c1cccc(F)c1)N1CCOCC1 +C=CCn1c(N)nnc1SCC(=O)Nc1cccc(C)c1C +O=C(Nc1cc[nH]n1)c1cnn(-c2cccc(Cl)c2)c1 +CCOC(=O)CCNC(=O)C1CCCN1C(=O)C1CCCCC1 +Cc1cc(Br)c(C)c2c1NC(=O)C2=O +Cc1ccc2nc(CNC(=O)c3cc(=O)[nH]c4ccccc34)cn2c1 +O=C(Nc1ccncc1)NC(CO)c1ccccc1 +CCCC(C)C(=O)Nc1nc(-c2c[nH]c(C(=O)OC)c2)cs1 +CC(c1ccccc1)N1CC(c2nc(-c3cnccn3)no2)C1 +CC1Sc2ccc(N)cc2N(Cc2ccccc2)C1=O +CCC(=O)Nc1cccc(NC(=O)c2cccc(OCC(F)F)n2)c1 +CN1CC(NC(=O)C2CC(=O)N(C)C2c2cccc(Cl)c2)CC1=O +CC1CC1CNC(=O)c1cccc(-n2cc(Br)cn2)c1 +Cc1noc(C(C)N2CCN(CC(=O)NCc3ccccn3)CC2)n1 +COc1ccc(C(O)CN2CCN(c3nccc(OC)n3)CC2)cc1 +CC(C)c1ccccc1NC(=O)N1CCOC(C(F)(F)F)C1 +Cc1cc(C(=O)N2CCC(C)CC2)nc(N2CCCCC2)n1 +NC(=O)C1(Oc2cccc(Br)c2)CCCCC1 +CCN(CC)C(=O)CCC(=O)Nc1ccc2c(c1)CCN2C(C)=O +CCOc1ccc(C(=O)Nc2cnn(CC3CCCO3)c2)cc1OC +NS(=O)(=O)c1cccc(NC(=O)C2CCCOC2)c1 +CC1CCc2c(-c3ccccc3)[nH]c(=O)c(C#N)c2C1 +COCC(C)N1CCN(Cc2cnc(C3CCCC3)s2)CC1 +CNC(=O)c1ccc(CNC(C)c2ccccc2C(F)(F)F)cc1 +CCOC(=O)c1cnc2c(-c3cccs3)c(C)nn2c1N +COC(=O)C1(CNC(=O)NCC(F)F)CCCCC1 +Cc1ccccc1C(=O)NC(C)(C)c1nc(C)c(C)s1 +CCCCC(=O)Nc1ccccc1C(=O)NC(C)(C)C +Cc1ccc2c(c1F)C(c1cccc(O)c1)NCC2 +CCOc1nc(N)nc2sc(C(=O)c3ccc(OC)cc3)c(N)c12 +Cc1cc(C(=O)Nc2cccc(OCC(=O)N3CCCC3)c2)[nH]n1 +Cn1c(CCNC(=O)Cc2cn3ccsc3n2)nc2ccccc21 +CC1CN(S(=O)(=O)c2ccccc2N)CCO1 +O=C(OCc1ccccc1)N1CCCCC1C(O)CCO +Cc1nc2c(cnn2C(C)C)cc1C(=O)NCC1CC1 +COc1cccc(NC(=O)C2CCCN2C(=O)c2cccs2)c1 +CC(NC(=O)CN1CCCCCC1=O)c1ccc(Cl)cc1 +COc1cc(NC(=O)NCc2cc(Cl)ccn2)ccc1NC(C)=O +Cc1ccnc(NC(=O)c2ccc(Br)cn2)c1 +CCOc1ccc(NC(=O)Cn2cc(C)c(N)n2)cc1 +CC(NC(=O)c1occc1COc1cccc(C#N)c1)C1CCCO1 +Cc1ccc(CC(=O)Nc2nnc(C3CCCCC3)o2)c(C)c1 +CCc1nnc(SCC2=CC(=O)N3C=CC=CC3N2)nc1CC +Nc1c(Br)cc(O)cc1Br +Cc1cc(C)c(NC(=O)c2coc(NC(=O)c3ccccc3)n2)c(C)c1 +Cc1cc(C)c(C(=O)Nc2ccc3c(c2)CCCO3)c(=O)[nH]1 +Cc1ccccc1C(C(=O)N(C)CCN1CCCCC1=O)N(C)C +CC(=O)NCC(=O)Nc1ccccc1OC1CCCC1 +COc1ccc(C(=O)NCCN2CCOCC2)cc1C +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)c1ccc(C#N)cc1 +CN1CCC(CNC(=O)N2CCC(C(N)=O)C2)c2ccccc21 +CCOCCC(=O)NCC(=O)Nc1ccc(Br)cc1C +COC(=O)c1ccc(OC(=O)CC(C)(C)C)cc1 +CN(C)S(=O)(=O)c1ccccc1CNCc1cccs1 +Cc1ccc(S(=O)(=O)N2CCCC(C(=O)NCCO)C2)s1 +Cc1cc(COC(=O)CN(C)c2ncccn2)no1 +O=C(C1CCOC1)N1CCN(c2nc3ccccc3o2)CC1 +O=c1c(Cl)c(NCCCn2cccn2)cnn1-c1ccccc1 +O=C(Cc1ccc(F)c(F)c1)NCC1CC(=O)Nc2ccccc21 +O=C(Cc1cccc(F)c1F)Nc1cnn(CC2CCCO2)c1 +O=C(CC1=CCCCC1)N1CC2COCC2(c2nnc(C3CC3)o2)C1 +Cc1nc(-c2ccc(NC(=O)c3cccc(N(C)C)c3)cc2)cs1 +CCCc1nc(COc2cccc(C(=O)N(C)C)c2)cs1 +COC(=O)c1cccc(Nc2nc(=O)[nH]nc2C)c1 +Cc1noc(C)c1CC(=O)N1CCN(c2ccccc2O)CC1 +O=c1ccc(CNCCc2nc3ccccc3[nH]2)c[nH]1 +Fc1cc(F)cc(-c2noc3ncnc(NCc4ccco4)c23)c1 +O=C1CC(c2ccccc2)c2ncn(-c3cccnc3)c2N1 +Fc1cc(CCNc2cnc3ccccc3n2)c2c(c1)COCO2 +Cc1nc(CCNC(=O)CCc2ccncc2)cs1 +CC1CC1C(=O)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1F +Cc1cc(CN(C)Cc2nc(COc3ccc(F)cc3)no2)no1 +Cc1cccc(-c2ocnc2C(=O)NCc2ccc(C)o2)c1 +O=C(Nc1c[nH]cc(Br)c1=O)c1ccco1 +Cc1ccc(CNC(=O)CCn2cnc3c(C)cccc3c2=O)s1 +COc1ccc(C(C)=O)cc1NS(=O)(=O)c1ccc(F)cc1 +CSc1cc(C(=O)OCC(=O)N2CCCCCC2)ccn1 +Cc1n[nH]c(SCCC(=O)NCc2cc3ccccc3o2)n1 +CNS(=O)(=O)c1cccc(S(=O)(=O)N(C)C)c1 +Cc1ccc(OCCNC(=O)C2(C)CC2(Cl)Cl)cc1 +N#Cc1cccc(OCc2noc(Cc3ccccc3)n2)c1 +CC1CCCCN1C(=O)NCc1ccc(C(=O)N(C)C)cc1 +O=C(CC1CSc2nc3c(c(=O)n21)CCCC3)NCc1ccco1 +NS(=O)(=O)CCCOC(=O)c1ccccc1C(F)(F)F +COC(=O)Nc1ccc(OC(=O)Cc2cccc(F)c2)cc1 +CC1CCC(NC(=O)C2CC2(Cl)Cl)CC1 +CCc1noc(CC)c1CC(=O)N(C1CC1)C(C)C1CC1 +O=C(NCc1cc(=O)[nH]c2ccccc12)N(Cc1ccccc1)C1CC1 +CC(=O)Nc1cccc(COC(=O)c2ncn(-c3ccccc3)n2)c1 +Cc1cc(C(O)CC(C)C)c2c(c1)C(C)(C)C(=O)N2 +O=C(NCc1ccc(F)cc1)c1nc(-c2cnccn2)no1 +CCC(=O)N1CCN(C(=O)NC(C)c2c(C)noc2C)CC1 +COc1cccc(CC(=O)N2CCCc3c(C(N)=O)cccc32)c1 +COc1c(NC(=O)c2ccn(-c3ccc(F)cc3)n2)c(C)nn1C +CCN(CC)S(=O)(=O)CCNC(=O)c1c(C)cc(C)cc1C +O=C1c2ccccc2NC(c2ncc[nH]2)N1c1ccc(F)cc1 +COC(=O)NCC(=O)N1CCC(NC(=O)C2CC2)CC1 +CC(O)CN1CCN(C(=O)Cc2cccc3ccccc23)CC1 +COc1ccc(NC(=O)NCC(O)(c2cccs2)C2CC2)cc1 +CN(Cc1ccccc1Cl)C(=O)c1ccsc1 +CCOC(=O)C(C)(NS(=O)(=O)c1cc(C)ccc1F)C(C)C +CC(C)C(Sc1nncn1C)C(=O)NC1CCCC1 +O=C(NCC(O)c1ccccc1)c1ccccc1F +O=C(CCSc1ccccn1)N1CCc2ccc(Cl)cc21 +COCc1nc(COc2ccccc2F)sc1CC#N +CCNC(=O)NCc1cccc(CN2CCOC(C)C2)c1 +Cc1nnc(SCC(=O)Nc2ccc3c(c2)CCC3)s1 +COc1cc(CNC(=O)Cn2c(C)nc3ccccc3c2=O)ccn1 +Cc1ccc(CN(C)C(=O)CCn2nnnc2CN2CCOCC2)o1 +CCOCCN(CC)C(=O)C1CC(=O)N(C)C1c1cccnc1 +Cc1cc(C(=O)NCC(=O)OCc2ccccc2)nn1C +Cc1noc2ncnc(Sc3ccccc3Cl)c12 +CCOCCCNC(=O)NCc1cc(F)cc(Br)c1 +Cc1cc(C(=O)NCCNC(=O)c2cccnc2)ccc1F +O=C(CSc1ccc(F)cc1)NC1CCCC(O)C1 +Cc1ccc(C)c(S(=O)(=O)Nc2ncccc2C)c1 +Cc1nnc(N2CCCC3(CN(Cc4ccccn4)CCO3)C2)o1 +CC(OC(=O)c1ccc(N2CCCC2)nc1)C1CCOC1 +Cc1noc(-c2nn(C)c3c2CN(C(=O)Cc2cccnc2)CC3)n1 +Nc1cc(C(=O)OC2CCCC2)c(Br)cc1F +Cc1nc(-c2ncccn2)[nH]c(=O)c1CC(=O)N=c1sccn1C +COc1ccc(C(=O)NC(CCC(C)C)C(C)(C)C)nn1 +O=C(Cn1nc(-c2ccc(F)cc2)ccc1=O)NC1CCCC1 +FC(F)(F)CNCc1cccc2c1OCCCO2 +O=C(CCc1cccs1)N1C2CCC1CC(O)C2 +Cc1ccccc1CN1CCN(S(=O)(=O)c2ccccc2)CC1 +O=S(=O)(c1ccc(Cl)cc1F)N1CCN(CCO)CC1 +CCc1cc(C(=O)N2CCCN(C(=O)c3ccncc3)CC2)[nH]n1 +CC(C)c1nnc2n1CC(NC(=O)Nc1ccccc1)CC2 +Cc1nccc(-c2cccc(NC(=O)C3CCC3)c2)n1 +CCCNC(=O)c1cnn(-c2ccc(F)cc2)c1C +O=C(Nc1cccnc1N1CCOCC1)c1cc(-c2ccco2)[nH]n1 +CSc1ncccc1C(=O)NCCc1ccc(O)cc1 +O=C(CN1CCN(c2nccs2)CC1)N1CCCCC1 +CCn1cc(C(=O)OCCCc2cccnc2)cn1 +CC(C)c1cccc(C(C)C)c1NC(=O)CCSc1nncs1 +CC1CCN(C(=O)c2ccc(-n3ccnn3)cc2)CC1 +Cc1ccccc1CC(=O)NCCCNS(C)(=O)=O +CCOC(=O)c1ccoc1CSc1nncn1-c1ccccc1F +Clc1cc(Cl)c2c(c1)CCNC2Cc1cccnc1 +CC(C)(C)c1nc(CNC(=O)COC2CCCC2)cs1 +CN(C)C(=O)c1cccc(OC(=O)CC(C)(C)C)c1 +CC(=O)Nc1ccc(OC(=O)Cc2c(C)noc2C)cc1 +NS(=O)(=O)c1ccc(CCNc2cc(=O)n3ccccc3n2)cc1 +O=C(NCC1COCCO1)c1[nH]c2ccccc2c1Cl +CN(CCCNC(=O)C1CCOC1)S(C)(=O)=O +C#Cc1cccc(N(CC(=O)NC)S(=O)(=O)c2cccc(F)c2)c1 +CN(C(=O)c1ccc(Cl)cn1)c1ccc(Cl)cn1 +COc1cccc(N2Cc3nc(=O)n(CC(C)C)n3C2=O)c1 +N#Cc1ccc(NC(=O)C(C(F)(F)F)C(F)(F)F)cc1 +Cc1cc(Br)cc(C)c1NC(=O)c1cccnc1 +CCc1nnc(SCc2cccc(OC)c2)n1N +COc1cccc(C2(NC(=O)c3cnc(C)nc3C)CCCC2)c1 +COc1cc(CNC(=O)NC(C)(C)c2nc(C)c(C)s2)ccn1 +Cc1ccc(S(=O)(=O)Nc2ccccc2C(=O)NCCO)cc1 +CCc1ccc(OCC(=O)Nc2cc(Cl)ccc2C(N)=O)cc1 +CC(C)c1ccc(CNC(C)(C)C(=O)N2CCC(O)CC2)cc1 +CCCc1nnc(NS(=O)(=O)c2ccc3c(c2)OCCO3)s1 +Cc1cc(NC(=O)c2cnn(Cc3ccccc3Cl)c2)ccn1 +Cc1ccccc1OCC(=O)Nc1cccn2ncnc12 +CCCCN(CC)c1cc2c(cc1N)CCC(=O)N2 +CCCC1COCCN1C(=O)c1ccc2cccnc2c1O +Cc1ccc(OCC(=O)N(C)C(C#N)c2ccccc2)cc1 +CCOC(=O)c1cccc(NC(=O)CSc2nc(N)cc(N)n2)c1 +N#Cc1ccc(NC(=O)C2CC2c2ccccc2)cc1 +C=CCN(CC=C)C(=O)C(C)NC(=O)c1ccccn1 +CCOC(=O)c1c(-c2ccccc2)nc2c(O)cccn12 +CCN(CC)C(=O)CCC(=O)Nc1ccc(SC)cc1 +Cc1ccc(NC(=O)CCc2c(C)nc3nc(C)nn3c2C)cc1 +COc1ccc(NC(=O)CCc2nc3ccccc3[nH]2)c(OC)c1 +COC(=O)C(NC(=O)CSc1ccccn1)c1ccccc1 +CCCn1cccc(-c2nnc(NCC)s2)c1=O +N#Cc1ccc(N2CCN(c3cccc(C(F)(F)F)n3)CC2)nc1 +COC(C)C(=O)N1CCCCC1c1nc2ccccc2s1 +Cn1nnnc1Sc1ccnc2cc(Cl)ccc12 +COc1cccc(-c2noc(C(=O)NCCCn3ccnc3C)n2)c1 +Cc1ccc(NC(=O)c2ccccc2S(=O)(=O)C(C)C)nc1 +COc1ccc(C)cc1S(=O)(=O)n1cccn1 +Cc1ccc(S(=O)(=O)N2CCCCC2C)cc1C +CCC1CN(CC(=O)Nc2c(C)nn(-c3ccccc3)c2C)CCO1 +Cc1ccc(NCC(=O)N(C)C)c(OCC(=O)N(C)C)c1 +Cc1nc(CCNC(=O)c2cc(C3CC3)nc3c2c(C)nn3C)n[nH]1 +CC(=O)C1Cc2c(Br)ccc(N)c2O1 +COc1ccc(-n2nnc(CO)c2COc2ccccc2)cc1 +COc1ccc(NC(=O)c2cc(CC(C)C)on2)cc1 +O=C(Nc1nnc(Cc2ccc(F)cc2)o1)c1ccc(F)cc1Cl +CCCNC(=O)N(Cc1ccncc1)Cc1ccco1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NC(C)c1cccc(F)c1 +CC(C)c1cc(NC(=O)CSc2nc3ccccc3o2)on1 +C#CCN(CC(=O)Nc1ccccc1)Cc1ccc(F)cc1 +CCC(C)NC(=O)NC(CC)c1ccccc1OC(F)F +CCC1CCCN(C(=O)Nc2ccc(OC)c(S(N)(=O)=O)c2)C1 +C#CCN1CCN(CC(=O)Nc2ccccc2-c2ccccc2)CC1 +COC(=O)C1CCCC1NC(=O)Nc1cc(F)c(OC)c(F)c1 +Cc1nn(-c2ccccc2)c(Oc2ccccc2)c1C#N +Cc1ccc(N2CCN(C(=O)C(C)(C)C)CC2)nn1 +CC1CN(C(=O)COc2cccc(S(C)(=O)=O)c2)CCO1 +COc1cccc(NC(=O)N(CCC#N)Cc2ccco2)c1 +COc1ccc(OC)c2c1cc(C(=O)Nc1nncs1)n2C +CCOCCCNC(=O)NC1CCCCNC1=O +Cc1cc(N2CCN(C(=O)CCc3scnc3C)CC2)nc(N)n1 +CC(=O)N1CCCc2ccc(NC(=O)C3CCCCC3)cc21 +CCC(CC)N(C)C(=O)c1cc(Br)c[nH]1 +CN(C)C(=O)CNC(=O)c1ccc2c(c1)OCO2 +Cc1ccc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c(C)c1 +CN(CCC(=O)Nc1cccc(F)c1)c1ccc(N)cn1 +Cc1ccccc1C(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CCOc1ccc(C2=CCN(C(=O)C(C)OCC3CC3)CC2)cc1 +CCn1cnnc1-c1cccc(NC(=O)c2cccc(F)c2)c1 +COc1nn(C)c2c1CCCN(C(=O)c1cc[nH]n1)C2 +CS(=O)(=O)c1cccc(OCCSc2ncccc2Cl)c1 +Cn1nc(-c2ccco2)cc1C(=O)Nc1cccc(C(F)(F)F)c1 +N#Cc1cccc(NC(=O)NCCCN2CCOCC2)c1 +CCOc1cc(N2CCOC(C)(c3cnn(C)c3)C2)ncn1 +Cn1cnc(-c2cccc(NC(=O)c3ccsc3)c2)n1 +O=C(NCc1ccc(Cl)cc1)NCc1cccnc1 +CC(=O)N(C)c1ccc(NC(=O)C2CCCO2)cc1 +N#CC1C(=O)Nc2nc3ccccc3n2C1c1c[nH]c2ccccc12 +CCN(C(=O)c1cc(COc2ccc(C(C)=O)cc2)on1)C(C)C +COCCN1CCCC2(CCN(C(=O)c3sccc3C)C2)C1=O +CCc1cnc(CN2CCN(C(=O)COc3ccccc3C)CC2)o1 +CC(C)COc1cccc(C2CC(=O)Nc3n[nH]cc32)c1 +O=C(CC1Oc2ccccc2NC1=O)Nc1nccs1 +CCCC(NC(C)=O)C(=O)N1CCCN(Cc2nccn2C)CC1 +COC(C(=O)NC1CCC(C)(C)c2ccccc21)c1ccccc1 +CC1CN(C(=O)CSc2ncnc3sccc23)CC(C)O1 +COc1ccnc(NC(=O)c2cc(-c3csc(C)n3)c[nH]2)c1 +Cc1cccc(C(=O)N2CCCC(CNS(C)(=O)=O)C2)c1 +Cc1csc(C(C#N)C(=O)C2CC(=O)N(C(C)C)C2)n1 +CCS(=O)(=O)c1cccnc1Oc1ccccc1 +CCN(CCC(=O)OC)C(=O)C1c2ccccc2Oc2ccccc21 +CN(CC(C)(C)O)C(=O)Cc1ccc(F)c(F)c1 +COC(=O)CCC(=O)N(c1ccccc1)c1nc(C)cs1 +CCCN(CC1CC1)C(=O)Nc1cccc(Cn2cccn2)c1 +CC(=O)Nc1ccc(NCCC(O)c2ccc(F)cc2)cc1 +NC(=O)COc1ccc(C(=O)NC2CCCCC2O)cc1 +Nc1ccc(Cl)cc1OCC(=O)N1CCCC1 +Cn1cc(C(=O)Nc2cccc(C#Cc3ccccn3)c2)cn1 +CNc1snc(C)c1C(=O)NCCOc1ccc2c(c1)CCC2 +CC(CNC(=O)c1cccc(C#N)c1)Oc1cccnc1 +CCCc1nc(C)c(C(=O)NCCNC(=O)c2ccc(O)cc2)s1 +CC(C)NC(=O)c1ccc(Cl)c(NC(=O)C2CC3CCC2O3)c1 +CC(C)(C)NC(=O)c1c(-c2cccnc2)cnnc1N +COc1ccc(CN(C)C(=O)CC2C=CCC2)cc1F +CCC(=O)N1CCCc2cc(NS(=O)(=O)c3ccccc3)ccc21 +O=C(CCn1cnnc1)Nc1ccc(Oc2ccccc2)cc1 +COc1ccccc1CNC(=O)c1cc(C)nn1C +CCC(C)NC(=O)CN1C(=O)COc2ccccc21 +CCCN(C)C(=O)Nc1cc(S(=O)(=O)N(C)C)ccc1N(C)C +COCc1nc(CN2CC(C)Oc3ccc(Cl)cc32)cs1 +CN(CC(=O)N(C)C1CCC(c2ccccc2)CC1)c1cnccn1 +Cn1ncc2c(=O)n(CC(=O)NCC(=O)NC3CC3)cnc21 +COc1cccc(C(=O)Nc2ccc(F)c(F)c2)c1OC +O=C(Cc1ccc(Cl)cc1)NCCNC(=O)c1ccc(O)cc1 +CC(=O)Oc1ccccc1-c1nncn1-c1ccccc1 +O=C(Nc1nc[nH]n1)c1ccc(-n2cncn2)cc1 +CCCCCCN1C(=O)COc2cc(CO)ccc21 +O=C1CCc2cc(C(=O)C3CCCCC3)ccc2N1 +CC(C)c1nc2ccc(NC(=O)NC3CCCCC3O)cc2s1 +CC(C)n1ccc2c(C(=O)N=c3[nH]cc[nH]3)cccc21 +CCOc1ccc(CC(=O)NCc2cc(=O)n(C)c(=O)n2C)cc1 +Cc1cc(C)cc(NC(=O)c2cc(Cl)ccc2-n2cnnn2)c1 +CSc1nnc(CSc2nnc(-c3ccco3)o2)s1 +CCOc1ccc(-c2ccc(SCC(N)=O)nn2)cc1 +O=C(CNC(=O)c1cc(C2CC2)[nH]n1)Nc1nccs1 +Cn1nnnc1SCCC(=O)Nc1nccs1 +CC(C)Cn1nccc1NC(=O)CC(C)NC(=O)c1ccccc1 +CSc1ccc(NC(=O)c2ccc(C(N)=O)nc2)cc1 +O=C1NCC(=O)N2CCN(C(=O)c3ccc4cc[nH]c4c3)CC12 +Cc1ccc(-c2nc(C)c(C(=O)OCC3CCC(=O)N3)s2)o1 +Cc1cncc(C2NCCc3ccc4[nH]ccc4c32)c1 +Cc1cccc(-c2nc(-c3cn(-c4ccccc4)nn3)no2)c1 +CC(C)(O)c1nnn(-c2nonc2N)c1C(C)(C)O +CCCN(CC(=O)OCC)C(=O)c1ccccc1F +O=C(CCCNC(=O)c1cccs1)Nc1ccc2c(c1)COC2 +c1ccc(-c2nnc(CSc3nnc(NC4CC4)s3)o2)cc1 +COc1cc(C(=O)N2CCCC2c2ccc[nH]2)cc(Cl)c1OC +CC(Sc1nncn1C)C(=O)Nc1ccc(CC#N)cc1 +CCN(Cc1cccc(F)c1)S(=O)(=O)c1cn[nH]c1 +O=C(Cc1csc(-n2cccc2)n1)NCc1cccs1 +O=C(Cc1cccnc1)N1CCCC(Cc2ccccn2)C1 +C=CCNS(=O)(=O)c1cccc(-c2nc(C(C)(C)OC)no2)c1 +CCc1cccc(NC(=O)CSc2nnc(C)n2-n2cccc2)c1 +CC(C)Cc1noc(CN2CCN(C(=O)c3ccco3)CC2)n1 +Cc1noc(C)c1Cn1nnc(C#N)c1-c1ccccc1 +COc1ccc2c(c1)CCCN2C(=O)NCC(C)(C)N1CCOCC1 +CC(N)c1cc(=O)n2nc(-c3cccnc3)cc2[nH]1 +CSc1nc2nccc(-c3ccc(Cl)cc3)n2n1 +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccc(Cl)c2cccnc12 +Cc1ccc(NS(=O)(=O)c2ccccc2N)c(C)c1 +Cn1nc2c(cc1=O)CN(Cc1cc(F)cc3cccnc13)CC2 +CCOc1ccc(C(C)NC(=O)c2cc(Cl)ccn2)cc1 +COC(=O)c1ccc(Cn2ccc(C)cc2=O)cc1F +COc1cc(C(=O)Nc2nc(CN3CCOCC3)cs2)ccc1C +O=C1CCC(c2nc(-c3ccncc3)no2)N1Cc1ccco1 +O=S(=O)(Cc1nc(-c2ccco2)no1)c1ccc2ccccc2c1 +CC(=O)Oc1ccc(N(C)S(=O)(=O)c2ccc(C)c(C)c2)cc1 +COc1cccc(C(=O)Nc2ncnc3c2CCC3)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccncc1 +CCCS(=O)(=O)Nc1cccc(C(=O)NC)c1 +CCN(CC)C(=O)CCCC(=O)N1CCOCC1C1CC1 +COc1cccc(C(=O)Nc2ncc3c(n2)CC(C)CC3=O)c1 +CN(CCN1CCc2ccccc21)c1ccccc1N +Cc1nc(CC(=O)N2CCC(C(N)=O)c3ccccc32)cs1 +COCc1oc(C)cc1-c1csc(NCC(C)C)n1 +CC(C)(O)c1sc(CCN2CCOCC2)nc1C1CC1 +Cc1cc(NCCc2ccncc2)n2nc(C)c(C)c2n1 +Cc1cc(CN(C)C(=O)CCc2c(C)nc3nc(N)nn3c2C)no1 +CCc1nc(Cn2ccnc2-c2ccnn2-c2ccccc2)no1 +CC(C)N(C(=O)Cn1c(=O)[nH]c2ccccc21)C1CCC1 +CC(=O)N(C)CC(=O)NCCc1nccn1Cc1ccccc1 +COc1ccc(-c2cc(C(=O)Nc3cccc(OC)c3)nn2C)cc1 +COc1ccccc1C1(CNC(=O)c2ccco2)CCCC1 +Cc1ccc(C(C)NC(=O)NCc2cccc(F)c2)o1 +OC1CCN(c2ncnc3sc4c(c23)CCC4)CC1 +CN(C)S(=O)(=O)N1CCc2c(nc(-c3ccccn3)[nH]c2=O)C1 +CCCn1nccc1C(=O)Nc1ccc(Br)cc1F +CC(=O)Nc1cc(C(=O)N(C)Cc2ccncc2)ccc1C +Cc1cnc(C2NCCc3cc(Cl)cc(F)c32)cn1 +COC(=O)N1CCC(NS(=O)(=O)c2ccccc2)CC1 +CNC(=O)CN1C(=O)CNc2cc(Cl)ccc21 +COc1cc(F)cc(NC(=O)c2cccc(OC)c2F)c1 +Fc1ccccc1-c1cnnc(NCCC2CC3C=CC2C3)n1 +COc1ccc(NC(=O)CNc2ccccc2N2CCCC2=O)cc1 +COCCNC(=O)CNC(=O)c1nc(SC)n2ccccc12 +CC(C)(C)C(=O)CSc1nnc(-c2cccs2)o1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NC1CCC(O)CC1 +CC1Cc2cc(S(N)(=O)=O)ccc2N1Cc1ccc(C(N)=O)cc1 +CCn1cc(C(=O)NCCc2c[nH]c3cc(F)ccc23)cn1 +O=C(OCc1nc2ccccc2s1)C1(O)CCCCC1 +COc1ccc(NC(=O)c2sc(-c3ccc(C)o3)nc2C)cn1 +O=S(=O)(c1cc(-c2nnc(C3CCC3)o2)co1)N1CCCCC1 +CCOC(=O)C(Cc1ccnn1C(C)(C)C)NC +Cc1cc(=O)c(C(=O)N2CCCCC2C)nn1-c1ccccc1Cl +Cc1cccc(OCCc2ncc(CC#N)s2)c1C +CC(C(=O)Nc1cccc(C#N)c1)n1cnc2ccccc21 +Cc1noc(CN2CCC(C(N)=O)c3ccccc32)n1 +COC(=O)C1(O)C2C=CC3C2C2C1C=CC2C3(O)C(=O)OC +COCCc1noc(CN2CCN(c3nccs3)CC2)n1 +O=C(Nc1ccc2c(c1)CCN2C(=O)C1CC1)C1CC1 +COc1cccc2c1N(C(=O)Cc1c(C)noc1C)CCC2 +Cc1ccccc1C(=O)NCC(=O)Nc1ccc2c(c1)COC2 +CCOC(=O)c1cnc(-c2ccccc2)nc1N1CCCCC1 +CCOC(=O)CNC(=O)N1CCc2sccc2C1C +NC(=O)c1ccnc(N2CCCC(c3ccn[nH]3)C2)c1 +CCc1ccc(C(=O)NCCNc2ccc(-n3cccn3)nn2)cc1 +Cc1cc(Cn2nnc3ccccc3c2=O)c2ccccc2n1 +N#Cc1ccc(NC(=O)c2ccc3c(c2)OCCO3)nc1 +CCn1cc(C(=O)Nc2cc(C(=O)OC)ccc2OC(C)C)cn1 +CCCn1cc(NC(C(N)=O)c2ccccc2)cn1 +CCCC(=O)N(c1nc(C)c(C(C)=O)s1)C1CC1 +Brc1cccc(NCc2ccc[nH]2)c1 +COc1cc2c(cc1CNC(=O)c1cccs1)OCCCO2 +Cc1c(Cl)cccc1NC(=O)c1noc2c1CCC2 +CCNC(=O)Cc1csc(-c2ccc(Cl)c(N)c2)n1 +N#CCCCOc1cccnc1NC(=O)Cc1cccc(F)c1 +COC(=O)CCn1c(-c2ccccc2N)nc2ccccc21 +CC(C)(C)S(=O)(=O)c1ccc(N2CCC(n3cncn3)CC2)cn1 +COC(=O)CSc1nc(-c2ccccc2OC)n[nH]1 +Cc1nc(C)c(CNC(=O)NC2CCCC(C(F)(F)F)C2)s1 +CCC(C)(C)C1CCC(NC(=O)c2ccc(C(N)=O)cn2)CC1 +CCOC(C)c1noc(Cn2nnc(-c3cccs3)n2)n1 +CC1CCCN(S(=O)(=O)NCC(C)N2CCc3ccccc32)C1 +N#CC(NC(=O)C1COCCO1)C1CCCCC1 +c1ccc(-c2cc3cc(-n4cnnn4)ccc3o2)cc1 +COc1ncccc1C(=O)Nc1c(C)cccc1C +CC(=O)NC(C)C(=O)NCc1csc(-c2ccccc2)n1 +Cc1c(C(=O)Nc2c(F)cccc2F)nnn1-c1ccccc1 +CC(=O)c1ccc(Cl)c(NC(=O)c2cccs2)c1 +O=C(NC(CO)Cc1ccccc1)c1ccc(F)cc1 +O=c1cc(CN2CCOCC2)n(CCOCCO)cc1O +CC(c1ccsc1)N1CCN(c2ccc(C#N)nc2)CC1 +Cc1ccc(NC(=O)NCc2ncc[nH]2)cc1C(=O)NC(C)C +Cc1nccc(CN(Cc2c(C)noc2C)Cc2c(C)noc2C)n1 +COc1ccsc1S(=O)(=O)NC1(C)Cc2ccccc2C1 +CCn1nc(C)c(NC(=O)CN(C)C(C)c2nccs2)c1C +CCc1ccc(C(=O)CCC(=O)Nc2nncs2)cc1 +COC(=O)c1cc2cn[nH]c2cc1Br +CCC(C)NC(=O)C(C)NC(=O)Cc1ccc(C)nc1 +O=C(c1ccc(F)c(F)c1)N1CCC(CN2CCOCC2)CC1 +O=C(NCc1ccc(N2CCCC2=O)cc1)c1ccc2ccccc2c1 +Cc1ccccc1N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +O=C1CCc2cc(C(=O)NCC3CCC3)ccc2N1 +CC(C)c1nnc(NC(=O)CN2CCOCC2C2CC2)s1 +Cc1cccc(Nc2nc(CC(=O)Nc3nnc(C)s3)cs2)n1 +CC(C)S(=O)(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +CC(=O)NC(C)C(=O)NCCCc1cn[nH]c1C +COC(=O)c1ccc2c(c1)C(c1cccnc1OC)NCC2 +COC(=O)C1(NC(=O)c2cnn(-c3ccccc3)n2)CCC(C)CC1 +Cc1cccc(NS(=O)(=O)c2ccc3c(c2)CCN3)n1 +COc1cccc2c1OCC(NCc1ccccc1OCCO)C2 +COc1ccccc1CNC(=O)c1cn(-c2ccc(F)c(C)c2)nn1 +CCOCCCn1c(CC)nc2ccc(Cl)cc21 +O=C1NCCC1NC(c1ccccc1)c1ccc(Br)cc1 +CC(c1ccsc1)N1CCN(C(=O)NC2CCOCC2)CC1 +COC(=O)CCNc1nc2c(Cl)c(C)nn2c2ccccc12 +CC(=O)NCC1NCCc2cc(F)cc(C(F)(F)F)c21 +CCCc1nnsc1C(=O)Nc1nnc(Cc2ccc(F)cc2)o1 +NC(=O)NCCCCC(=O)Nc1cccc(Cl)c1 +CC(C)N(CCc1nc2ccccc2c(=O)[nH]1)Cc1ccccc1 +Cc1cc(NC(=O)c2ccc(F)c(F)c2)ccc1C(=O)N(C)C +COc1ccc(-c2cn3c(C)c(C(=O)NC(C)C)sc3n2)cc1 +NC(=O)N1CCCN(C(=O)Nc2cc(-n3cccc3)ccc2F)CC1 +O=C(OCc1cncs1)c1cccc2cc[nH]c12 +Cc1cc(C(=O)NCCc2n[nH]c(C)n2)c2cccc(C)c2n1 +CCCCC(=O)N1CCC(S(=O)(=O)c2ccc(F)cc2)CC1 +Cc1cc(C)cc(CCNC(=O)c2cnn(C)c2C)c1 +COc1ccccc1CC(C)CC(=O)Nc1c(C)nn(C(C)C)c1C +CC(C)n1c(SCCn2cccn2)nc2ccccc2c1=O +COCC(NC(=O)C1CC1c1ccc(F)cc1)C(N)=O +Cc1cc(C)cc(N2CCN(C(=O)Cc3cccc(O)c3)CC2=O)c1 +COCCS(=O)(=O)N1CCC(NC(=O)c2cccc(F)c2)CC1 +Cc1cc(C)cc(NC(=O)c2c(C)cc(C)[nH]c2=O)c1 +CCN(CC)C(=O)CSc1nnc(-c2ccccc2C)n1CC +CCN(CCO)C(=O)c1cc(C)nc2onc(C)c12 +COC(=O)CS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +CS(=O)(=O)c1ccc(CC(=O)Nc2ccc(F)cc2F)cc1 +CC(C)(C)OC(=O)Cn1ncc(Cl)c(Cl)c1=O +CC(C)OCCC(=O)Oc1cccc(-n2cccn2)c1 +CCCOCc1nc2ccc(C(C)C)cc2c(=O)[nH]1 +N#CCC(=O)Nc1cc(S(=O)(=O)N2CCOCC2)ccc1O +O=S(=O)(NCc1nnc2n1CCC2)c1ccc2c(c1)CCO2 +Cc1cc(F)ccc1NC(=O)NCc1cccc(S(N)(=O)=O)c1 +Cc1noc(C)c1CN(C)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +CC(C(=O)N1CCc2sccc2C1)n1c(=O)oc2ccccc21 +Cc1ocnc1CNC(=O)Nc1ccc(C(C)C)cc1 +Cc1oc(-c2ccccc2)nc1CN1CCOCC1C1CC1 +CC(=O)c1csc(COc2cccc(C)c2C)n1 +O=S(=O)(NC1CCCc2occc21)c1ccc2c(c1)OCCCO2 +CC(CCc1ccco1)NC(=O)C1CCN(C)C(=O)C1 +O=C(CN1CCN(Cc2ccccc2F)C1=O)NCc1ccccc1 +CN(C)c1cncc(C2CCCN2S(=O)(=O)c2cn[nH]c2)n1 +Cc1nn(CC(=O)NCCN2CCOCC2)c(C)c1Br +CC(C)CC(C(=O)N1CCCCC1)N1Cc2ccccc2C1=O +O=C(CCOc1ccc(Cl)c(Cl)c1)NCCc1ccccn1 +CCCS(=O)(=O)NC1CCSc2ccc(F)cc21 +Nc1cccc(OCCNc2ccc(Cl)cc2)c1 +N#CCn1nnc(CO)c1-c1ccc(Br)cc1 +CN1C(=O)CCOc2c(Br)cc(N)cc21 +COC(=O)Cn1nc(CO)cc1-c1ccc(C)c(C)c1 +CC(C)(C)S(=O)(=O)c1ccc(NCc2ccco2)nn1 +C=CCNC(=O)COc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CSc1cccc(CN(C)C(=O)c2cccnn2)c1 +O=C(c1ccc2c(c1)CCC2)N1CCOCC1C1CC1 +CCc1nnc2n1CCN(C(=O)Cc1cn3ccsc3n1)C2 +O=C(COc1cccc(C(=O)NC2CC2)c1)Nc1ccccc1 +O=C(OCc1csc(-c2ccccn2)n1)C1CC1 +CC(C)Sc1ccccc1C(=O)Nc1cccnc1 +Cc1ccc(OCC(N)=O)c(-c2cccc3[nH]ccc23)c1 +CN(CC1COc2ccccc2O1)C(=O)c1cc(-c2ccccc2)[nH]n1 +O=C(Nc1c(O)c(Cl)cc(Cl)c1Cl)C1CCOC1 +COCc1ccccc1CNC(=O)c1c(F)cccc1F +CC(O)CC(C)CNC(=O)CC12CC3CC(CC(C3)C1)C2 +CCc1nc2n(n1)CCCC2NC(=O)c1sc(C(C)OC)nc1C +CC1CN(C(=O)CCNC(=O)OC(C)(C)C)c2ccccc2S1 +Cc1c(Cl)cccc1NC(=O)CNc1ncccn1 +CCc1nnc2n1CCN(C(=O)Cn1cc(C)c3ccccc31)C2 +CCOC(=O)c1cc(Cl)c(NC(=O)CC)cc1OC +Fc1cc(Br)c2c(c1)CCNC2c1cc[nH]n1 +Cc1nc(N)cc(-c2ccc3c(c2)N(C)C(=O)CCO3)n1 +CCC(=O)N1CCCN(c2ccc(=O)n(-c3ccccc3)n2)CC1 +Cc1cccc(CN(CC2CCCO2)C(=O)CCc2ccncc2)c1 +O=C(NCc1cc(Cl)c2c(c1)OCCO2)C1CC2CCC1O2 +CCc1cccc(OCCN2CCN(CC(N)=O)CC2)c1 +O=C(CNC(=O)c1ccccc1)c1ccc2c(c1)OCCO2 +Cc1ccc(C(=O)OCC(=O)NCCc2ccccc2)s1 +Cc1cc(C(=O)NCCn2nc(-n3cccn3)ccc2=O)c(C)o1 +O=C(Cc1ccc(F)cc1F)Nc1nc(C2CC2)cs1 +Cc1cc(C(CO)Nc2cccc(F)c2)c(C)s1 +CC(C)(C)OC(=O)N1CCC2(CCC(=O)CC2)CC1 +COC(=O)CN(c1ccccc1C)S(=O)(=O)c1cccs1 +Cc1ccc(-n2c(=O)n(C(C)C)c(=O)c3c2ncn3CC2CC2)cc1 +Cc1cc(C)n2nc(C(=O)Nc3cc(Cl)ccc3C(N)=O)nc2n1 +COC(=O)CSc1nc(NC2CC2)c2ccccc2n1 +CCC(=O)N1CCC(c2nccnc2Nc2cnccn2)CC1 +Cc1ccc(S(=O)(=O)N(C)C(C)CC#N)c(C)c1 +CC(=O)N1CCCc2cc(S(=O)(=O)Nc3ccc(C)cc3)ccc21 +Cc1ccc(C)c(OCc2nc(C)c(C#N)s2)c1 +Nc1cc2c(cc1Sc1ccccc1)NC(=O)CO2 +CCCCNc1ncnc(Sc2ccccc2)c1N +CC1CN(C(=O)Nc2cccc(Cl)c2-n2cccn2)CC(C)O1 +CCS(=O)(=O)N1CCC2C(=O)NCC(COC)C2CC1 +O=C1CCc2cc(OC(=O)CCC3CCCC3)ccc2N1 +CCOC(=O)NCCC(=O)Nc1ccc(CC#N)cc1 +O=C(c1cn2c3c(cccc3c1=O)CC2)N1CCCCC1 +CCCN(CCC)C(=O)c1cc(Br)cn1C +COCC1CCN(C(=O)c2cn(CCCc3ccccc3)nn2)C1 +Cc1nnc(NC(=O)NCc2sccc2C)s1 +COC(=O)CN(C)C(=O)c1ccc(SCc2nc(C)no2)cc1 +COCCC(=O)N1CCC2(CCCN(Cc3ccc(F)cc3)C2=O)C1 +Cc1nnc(NCC(C)Cn2cccn2)c(C#N)c1C +CSc1ccc(C(O)CNC(=O)c2cccc(N(C)C)c2)cc1 +CC(C)(C)C(=O)NCC(=O)N1CCN(c2ncccn2)CC1 +Cc1nc2c(N(C)Cc3c(C)noc3C)ncnc2o1 +Cn1cc(CNc2ccc(Cl)c3cccnc23)cn1 +CC(=O)N1CCCC(Cc2ccc(C(=O)NC3CCCC3)nn2)C1 +O=S(=O)(c1cccs1)n1ccc(-c2ccc3c(c2)CCO3)n1 +Cc1c(C(=O)NCC(C)CN2CCOCC2)cnn1-c1ccncc1 +O=C(NCc1ccccn1)c1coc(=O)c(Br)c1 +O=C(NCCNC(=O)c1ccoc1)c1ccc(C(F)(F)F)cc1 +Cc1n[nH]c2c(N3CCN(Cc4ccccc4)CC3)ncnc12 +CCCC(=O)N1CCN(c2cc(N3CCCCC3)nc(C)n2)CC1 +CCCn1nc(C(=O)Nc2cccc3ncccc23)ccc1=O +CC(=O)Nc1ccc(OC(C)C(=O)NC(C)c2ccccc2C)cc1 +Cc1nn2cccnc2c1C(=O)NC1CCc2c(Cl)cccc21 +CC(c1ccccn1)N1CCN(C(=O)c2ccc(C#N)cc2)CC1 +O=C(c1cnc[nH]1)N1CCOC(c2cc(F)c(Cl)cc2Cl)C1 +O=C(Nc1nnc(C=Cc2ccc3c(c2)OCO3)s1)c1ccco1 +Cc1cc(CSc2nnc(COc3ccccc3)n2N)no1 +N#Cc1ccc(Cl)cc1Sc1ccncc1N +COc1cc2c(c(OC)c1OC)CCNC2c1cc[nH]n1 +Cc1csc(C2CN(CC(=O)Nc3nccs3)CCO2)n1 +Brc1ccc(OCCSc2ncn[nH]2)cc1 +O=c1c2ccccc2ncn1CC(O)c1cccc(F)c1 +CCn1cc(CN(C)C(=O)c2cc(Cl)ccc2Cl)cn1 +COCCCN(C)C(=O)Cc1c(C)nn(-c2ccccc2)c1C +OCCNc1nc2ccccc2n1CCOc1ccccc1 +CNC(=O)c1cccc(CNc2cc3c(cc2Cl)NC(=O)CO3)c1 +COc1cccc2c1N(Cc1nc(C)c(C)o1)CCC2 +NC(=O)Cc1cccc(OS(=O)(=O)c2ccc3c(c2)CCC3)c1 +COc1ccc(C(=O)NCCCn2cccc2)c(OC)c1 +CCOC(=O)CN(C(=O)NC1CCCCC1)C(C)C +COc1ccccc1NC1CCN(C(=O)Cc2ccc[nH]2)CC1 +CCC(=O)Oc1ccc2c3c(c(=O)oc2c1)CCCC3 +CCNc1ccc(Cl)cc1C(=O)NCC1CCOC1 +CC1CCCC(NC(=O)c2cccc(N3CCCS3(=O)=O)c2)C1 +COc1cccc(CN(C)c2ncnc3c2cnn3C)c1OC +Cc1n[nH]c(C)c1S(=O)(=O)NCCC(=O)N(C)C +Nc1nncc(-c2ccc(OC3CCCC3)cc2)n1 +O=C(NCC1COCc2nc3cc(F)ccc3n21)c1ccc(F)cc1 +CC(O)(CNC(=O)c1cc2ccccc2o1)c1cccs1 +COc1ccc(CNC(=O)c2cc(C(=O)C3CCCCC3)c[nH]2)cc1 +OCC1NCCc2c(Br)ccc(Cl)c21 +C=C(C)CNc1cc(S(=O)(=O)N(C)C)ccc1NCC +N#Cc1ccc(NCCC(=O)c2cccc(N)c2)cc1 +CN1C(=O)Cc2cc(C34CCC(=O)N3CCCN4)ccc21 +CCOc1ccc(F)c(C(=O)N2CCN(c3ccccc3)CC2)c1F +CC(CO)NS(=O)(=O)c1ccc2c(c1)N(C)C(=O)C(C)O2 +CC1CCC(NC(=O)CCN2C(=O)CCc3ccccc32)CC1 +Fc1ccc(NCc2cccc3c2OCO3)cc1F +CCS(=O)(=O)c1ccccc1C(=O)NCCc1ccccn1 +OCCn1ncc2c(N3CCC4CCCCC4C3)ncnc21 +CC(N1CCN(C(=O)CCSc2ccccn2)CC1)C(F)(F)F +Cc1nc(C(=O)Nc2ccc(N(C)C)cn2)cs1 +Cc1nnc(SCC(=O)NCC2(Cn3cccn3)CC2)s1 +COc1nc(C)nc(N2CCCC(c3nncn3C3CC3)C2)c1C +CCN(C)C(=O)CCNS(=O)(=O)c1ccc(F)c(F)c1 +CC(=O)Nc1ccc(OC(=O)C2(c3ccccc3)CC2)cc1 +Cc1nc(CNc2ccc(CC(=O)N(C)C)cc2)cs1 +CC(=O)OCCCCn1c(=O)c(N)c(N)c2cccnc21 +COCc1cccc(NC(C)c2nnc(-c3ccccc3)o2)c1 +CC(=O)NCCNC(=O)c1ccc2c(c1)N(C)C(=O)CO2 +CCc1nc(CSc2nnnn2-c2cccc(Cl)c2)cs1 +Cc1ccc(Cl)cc1NCC(=O)N1CCOCC1 +c1cncc(C2CN(Cc3nc4c(s3)CCCC4)CCO2)c1 +Cc1cc(C(=O)N(C)CCc2ccc(F)cc2)no1 +CCCC(=O)Nc1cccc(NC(=O)Cc2c(C)nc(C)[nH]c2=O)c1 +Cc1cccc(CNC(=O)N2CCN(Cc3cccnc3)CC2)c1 +CC1(C)CN(C(=O)NCCc2cc(F)cc3c2OCOC3)CCO1 +CCc1ccc(CCC(=O)N2CCC(CO)C2)cc1 +Cc1cc(Br)cc(C)c1NCC(=O)NC1CCCC1 +CCCNc1nc(Cc2ccccn2)nc(C)c1C +COc1ccc(NC(=O)N2CCC(n3c(C)ccc3C)CC2)cc1 +COc1cc(C#N)ccc1OCCn1ccc(-c2ccc(F)cc2)n1 +O=C(Nc1cc(Cl)ccc1F)c1ccccc1-n1cccn1 +O=C(COc1ccc(C(=O)c2ccccc2)cc1)NCC1CCCO1 +CCc1cccc2c1N(S(=O)(=O)c1cn(C)c(=O)n(C)c1=O)CC2 +CC1COCC(C)N1C(=O)CNC(=O)NCc1ccco1 +CSc1nnc(Cn2nnc(-c3ccccc3C)n2)s1 +CC(C)NC(=O)c1ccc(COc2ccccc2C#N)o1 +CC(C)NC(=O)N1CCC(CN2CCOCC2)CC1 +Cc1cccc(S(=O)(=O)NCC(O)c2ccccc2)c1 +COc1ccc(NC(=O)Nc2cc(N3CCCCC3)ncn2)cc1 +CC(C)(C)c1cc(C(=O)N2CCN(C(=O)c3ccco3)CC2)[nH]n1 +CCc1ccc(C(=O)NCCCC2(C3OCCO3)CCOCC2)cc1 +C=CCN(CC=C)C(=O)C1CC1c1ccccc1F +Cc1ccccc1Cn1ccc(NS(C)(=O)=O)n1 +CC(C)COc1ccccc1NC(=O)NCC(C)(C)N1CCOCC1 +O=C(C1CCCCC1)N1CC(c2nc(-c3cccs3)no2)C1 +COc1ccc(CCC(=O)Nc2nc(C)c(C(=O)N(C)C)s2)cc1 +CNC(=O)c1cccc(CSc2nc3ccccc3o2)c1 +Cc1ccc(-n2cnnn2)cc1NC(=O)Cc1cccs1 +Cn1ncc(-c2ccc3c(c2)CCCC3)c(N)c1=O +O=C(Nc1ccc(OC(F)(F)F)cc1)c1c[nH]ccc1=O +O=C(Cn1cnc2ccccc21)NCC#Cc1ccc(F)cc1 +CCc1nnsc1C(=O)NCC1Cc2ccccc2O1 +CC(C)c1noc(CCC(=O)N2CCOCC2C2CC2)n1 +CS(=O)(=O)N1CCC(C(=O)Nc2cccc(F)c2)CC1 +CN(C)C(=O)CCNC(=O)NCC12CC3CC(CC(C3)C1)C2 +Cc1cc(C(F)(F)F)nc2nn3cc(CCO)cnc3c12 +COC1CCN(Cc2nc3ccccc3s2)CC1 +CC(C)(C)c1n[nH]cc1CN1CCN(C(=O)c2cccc(O)c2)CC1 +Cn1c(SCc2ccccn2)nnc1C(F)F +COc1cc(C)c(NC(=O)c2cc(=O)[nH]c(C)n2)cc1C(C)C +CCc1ccc2c(CNc3c(C)cccc3C(N)=O)cc(=O)oc2c1 +CC(C)n1nnnc1-c1cccc(C(=O)N(C)c2ccccc2)c1 +CC(=O)NC1CCN(C(=O)Nc2cc(Cl)ccc2N(C)C)CC1 +Cc1ccc(C(=O)NCC(=O)Nc2cccc(C#N)c2)cc1C +Cc1cc(C)n(CCCNC(=O)CNC(=O)c2ccc(C)c(C)c2)n1 +CCN(CC(=O)OC)C(=O)Nc1cc(Cl)ccc1Cl +COc1ccc(NC(=O)N2CCN(c3ccccc3)CC2)cc1 +C=CCN(Cc1ccccc1)C(=O)c1ccc(F)nc1 +O=C(c1ccccc1-n1cnnn1)N1CCCC1Cn1cccn1 +Cc1noc(C)c1CN(C)C(=O)CSc1nc2ccccc2o1 +CC(C)COC1CC2(CCN(C(=O)c3cscn3)CC2)C1 +CNC(=O)Cc1ccc(NC(C)C(=O)Nc2cccc(C)c2)cc1 +O=C(CC1CCCN1C(=O)c1ccccc1)c1ccccc1 +CCN1CC(C(=O)N2CCc3sc(C(=O)NC)cc3C2)CCC1=O +Cc1cccc(N2CCN(CC(=O)NC3CC3)CC2)c1C +O=C(NC(c1ccccc1)c1ccccc1)N1CCN(CCO)CC1 +Nc1cnc(N2CCN(CCO)CC2)c(Br)c1 +CC(C)(C)NC(=O)Nc1cccc(NC(=O)c2cccs2)c1 +CC1COCC(C)N1C(=O)c1cc(-c2ccco2)nc2ccccc12 +CCOc1ccccc1NC(=O)c1c(C)nn(-c2ccccc2)c1C +CCc1nn(-c2ccc(OC)cc2)c(CC)c1C(=O)N1CCOCC1 +COc1ccc(F)cc1-c1csc(NC(=O)c2ccccn2)n1 +CC(=O)N(C)CC(=O)NCc1c(C)cc(C)cc1C +O=C(Nc1cccc(Cl)c1F)C1CC1c1ccco1 +O=C(CC1CCCC1)N1CCCN(C(=O)c2ccccc2Cl)CC1 +Cc1nn2ccccc2c1C(=O)NCCC(=O)Nc1nccs1 +O=C(NCc1nc(-c2ccccc2)no1)c1cccs1 +CC(=O)NC1CCOc2c1cc(F)cc2C(O)C(C)C +O=C(NC1CCOC2(CCN(c3ncccn3)C2)C1)c1ccncc1 +COc1ccc2nc(SC(C(=O)N3CCOCC3)C(C)C)[nH]c2c1 +Cc1cc(C2CCC2)nc(N(C)CCc2ccccn2)n1 +CC(C)n1ncc2c(C(=O)NC3(C#N)CCCC3)cc(C3CC3)nc21 +O=C(NCCOc1cccc(Br)c1)C1CC=CC1 +CN(Cc1ccc(C(C)(C)C)cc1)C(=O)c1ccn(C)c(=O)c1 +Cc1nnc(SCC(=O)Nc2nc(C(C)(C)C)cs2)o1 +c1ccc(-n2ccc(CSc3nnc(Cn4cncn4)o3)n2)cc1 +CCN(CC)S(=O)(=O)c1cc(C(=O)NC(C)CO)ccc1Cl +CCCC(=O)Nc1ccc(C)c(S(=O)(=O)NC2CC2)c1 +O=C(CCCNc1ncnc2ncccc12)N1CCc2ccccc2C1 +Cc1cccc(OC(=O)c2cnn(C(C)(C)C)c2)c1 +O=C1c2ccccc2NC(c2cccc(O)c2)N1CCc1ccccc1 +O=C(CN1C(=O)CSc2ccccc21)NCc1ccccc1 +CNC(=O)NCC(=O)N1CCC(c2ccccc2)C1 +c1ccc(CNc2c3c(nc4nncn24)CCC3)cc1 +CC1CC1C(=O)NC(c1ccc(F)cc1)C1CCCO1 +O=C(NCCNc1ccc(C(F)(F)F)cn1)c1cccnc1 +O=C(NC1CCc2ccccc21)c1ccc[nH]c1=O +COCCOc1ccccc1C(=O)N1CCOCC1CC(C)C +CCc1ccccc1NC(=O)NCc1ccc(S(C)(=O)=O)cc1 +CCN(Cc1cccs1)c1ccc(F)cc1C(C)O +O=S(=O)(NC(C1CC1)C1CC1)N1CCCCCC1 +COc1ccc(-c2ccc(C#N)c(SCC(N)=O)n2)cc1 +O=C(CSc1ccncc1)Nc1ccccc1F +CCOc1ccc(-c2cc(N)[nH]n2)cc1NC(C)=O +COc1cccc(CC(=O)N(C)Cc2cc(C)on2)c1 +CN(C)C(CNc1ccc2nnnn2n1)c1cccs1 +Cc1cc(Cl)ccc1-n1nnc(CO)c1-c1ccncc1 +COC(=O)c1cc(=O)nc(NCc2ccccc2)s1 +Cc1ccc(CN2CCc3nnc(CN4CCCC4=O)n3CC2)o1 +CCCNC(=O)NC1CCSc2ccc(F)cc21 +Cn1cnc2cc(OC(=O)c3ccc4[nH]cnc4c3)ccc21 +CCOc1ccc(-c2cn3c(nc4cc(N)ccc43)[nH]2)cc1OC +Cc1cccc2nc(COc3ccc(-n4cnnn4)cc3)cn12 +C=CCNC(NC(=O)c1ccc(OC)cc1)C(Cl)(Cl)Cl +COc1cccc(CNc2cccc(-c3nnnn3C)c2)c1 +COc1ccccc1C1CC1C(=O)NCC(O)c1cccc(F)c1 +CC(NCc1nnc2n1CCCC2)c1nc(C(C)(C)C)no1 +O=C(CC1CC(=O)Oc2ccccc21)NCCN1CCOCC1 +c1ccc2c(c1)CCCC2N1CCN(c2ccc3nncn3n2)CC1 +Cc1ccc(C)c(S(=O)(=O)NCCC(=O)NCc2ccccn2)c1 +Cc1ncccc1CN1CCOC(c2cccc(F)c2)C1 +CCN1CC2CCN(C(=O)c3cnc(C)cn3)CCC2S1(=O)=O +Cc1cc(C(C)NC(=O)N2CCN(S(C)(=O)=O)CC2)c(C)o1 +CN(Cc1nc2c(s1)CCCC2)CC(O)c1ccc(C#N)cc1 +CCc1nc(OCC(=O)NCc2ccc(C)o2)c2c(C)c(C)oc2n1 +Cc1noc2nc(-c3ccccc3)cc(C(F)F)c12 +O=C(NCC1CCCO1)c1cc(-c2cccs2)nc2ccccc12 +O=C(CSc1nc(-c2ccco2)n[nH]1)Nc1nccs1 +CCc1ccc(C2COCCN2Cc2scnc2C)o1 +O=C(NCCCc1ccccc1)c1csc(-n2cccc2)n1 +Cc1cc(CNC(=O)Cc2cn3ccsc3n2)ccc1F +CC(=O)NC(C)Cc1cccc(Br)c1 +Cc1cc(C)n2c(=O)n(CC(=O)Nc3ccc(Cl)cc3)nc2n1 +Cc1ccc(OCCNC(=O)CCC(=O)N2CCOCC2)cc1 +Cc1ccc(C(=O)Nn2cnc3ccccc32)cc1 +Cc1cccc(-n2nnnc2SC(C)C(=O)N(C)C)c1 +CC(=O)Nc1c(Cl)cc(Cl)c(O)c1Cl +Cc1sc(CC(=O)NCc2ccccc2)nc1-c1ccccc1 +O=S(=O)(Cc1ccccc1C1OCCO1)c1ccccc1 +O=C(Cn1c(=O)ccn(Cc2ccccc2)c1=O)NC1CCCCC1 +COc1c(Cl)cccc1NCC(=O)NC1(C#N)CCCC1 +Cc1cccc(N2CCN(C(=O)CCc3ccco3)CC2)c1C +Cc1ccsc1CNc1cccc(C(=O)N2CCOCC2)c1C +Cc1ccccc1OCC(=O)Nc1ccc2c(c1)OCO2 +COc1cccc(OC(C)C(=O)NCC2CCCO2)c1 +OCc1ccc(Br)cc1N1CCOCC1 +CN(CC(O)C1CC1)C(=O)c1[nH]nc2c1CCCC2 +Cn1c(=O)c2c(N3CCCCC3)ccnc2n(C)c1=O +O=C(NCc1ccccc1)C1CC(=O)N(Cc2ccc(F)cc2)C1 +COCc1ccccc1CNC(=O)Cn1ccc(C)cc1=O +Cc1cc(C(=O)NCC(C)c2nc(-c3ccccc3)no2)no1 +COc1cc(-c2noc(-c3cccc4c3ccn4C)n2)ccn1 +COc1ccc(Cc2nc3c(N)cccc3[nH]2)cc1 +O=C(COc1ccc(F)cc1F)NC1CCCCC1 +CC(C)c1ccc(OCC(=O)Nc2ccccc2C(=O)N(C)C)cc1 +CC(=O)c1cc(Cl)ccc1OC1CCCCC1O +CCCOc1ccc(S(=O)(=O)N2CCOCC2)cc1 +CC(NC(=O)C1CCCCN1C(=O)c1cccs1)c1ccccc1 +CC(C)(C)C(=O)N1CCC(C(=O)N2CCOc3ccc(F)cc32)CC1 +CCc1ccc(NCc2cc(OC)c(O)c(OC)c2)cc1 +CC(C)CCOC1CCCCC1NC(=O)Cn1ccnn1 +Cc1cc(Br)ccc1NS(=O)(=O)c1cnn(C)c1 +CCC(=O)N1CC(CC)(CC)Oc2ccc(S(N)(=O)=O)cc21 +CC(Sc1ncc(-c2ccccc2)n1C)C(=O)N(C)C +Cc1ccc(-n2nc(C)cc2NC(=O)CCC2CC2)nn1 +CCN(C)C(=O)CCNS(=O)(=O)c1ccccc1 +CCN1CC(C(=O)Nc2ccccc2C(=O)OC)CC1=O +COc1ccc(SCC(=O)Oc2ccc(C#N)cc2)cc1 +CSc1ccc(CC(=O)Nc2ccc(C(C)=O)cc2)cc1 +CCCNc1snnc1CN1CCOC2CCCC21 +CCn1c(SCC(=O)NC2CC2)nnc1-c1ccccc1 +CCCn1nc(C(=O)Nc2c[nH]nc2C)ccc1=O +COCC1CN(Cc2cc(C)on2)Cc2cn(C)nc21 +CCN(C(=O)CSc1nnnn1-c1ccccc1)C1CCCCC1 +Cc1nc2c(NC3CCN(C(=O)c4ccoc4)CC3)cccn2n1 +Nc1cccc(C(=O)N(CCO)C2CCCCC2)c1 +CCCN(CC(F)(F)F)C(=O)c1[nH]c(C)c(C(=O)OC)c1C +O=C(NCCc1ccccc1F)c1cccnc1N1CCCC1 +CC1CN(Cc2cccc(OCC#N)c2)CC(C)O1 +COCCNC(=O)c1cc(N(C)S(C)(=O)=O)ccc1OC +COc1ccc(S(=O)(=O)Oc2ccc3ccc(=O)oc3c2)cc1C +Cc1cccc(CNC(=O)C2CCN(S(C)(=O)=O)CC2)c1 +Cc1ccc(C)n1C1CCN(CCS(=O)(=O)c2ccccc2)CC1 +CC(C)c1[nH]nc(C(=O)NCc2ccnn2C)c1N +COc1cccc(CNC(=O)c2ccc(C#N)cc2)c1OC +O=C(Cn1c(=O)n(-c2ccccc2)c2ncccc21)Nc1ccccc1 +Clc1ccc(N2CCCC2)c(NCc2nnnn2C2CC2)c1 +O=C(COc1ncccn1)Nc1ccc(Cl)cc1 +COCCN1CCN(C(=O)Nc2cc(F)cc(Cl)c2)CC1=O +N#Cc1ccsc1NC(=O)c1cccc(OCc2cscn2)c1 +CC1(CNc2nc3nonc3nc2N2CCCCCC2)COC1 +CCc1sc(C(=O)Nc2nc(C)no2)cc1C +COc1ccc(C2(C(=O)N3CCN(C)CC3)CC2)cc1 +O=C(Nc1cnccc1Oc1ccccc1)c1cc(C2CC2)[nH]n1 +CC(C)(C)OC(=O)N1CCN(c2cn[nH]c(=O)n2)CC1 +O=C(CNc1ccccc1Cl)Nc1ccc2c(c1)OCO2 +Cc1cc(F)ccc1NC(=O)CN1CCCC1=O +Cc1nc(CNC(=O)NCC(C)N(C)c2ccccc2)cs1 +Cc1cc(NC(=O)c2ccco2)n(-c2nc3c(F)cccc3s2)n1 +Cc1nscc1C(=O)Nc1ccc(C(N)=O)cc1 +CCCNC(=O)c1nc(C)n(-c2c(Cl)cccc2Cl)n1 +O=C(NCCc1ccc(-n2cccn2)cc1)c1ccc(F)cc1Cl +Cn1cc(C(N)=O)cc1C(=O)OCCCC1CCCCC1 +COCCOc1ccccc1NC(=O)CC(C)(C)C +CN(C)S(=O)(=O)NCC#CCOc1cccnc1 +CC(C)n1nccc1NC(=O)CCN1C(=O)COc2ccccc21 +Cc1cc(C(=O)N2CC(C)CC(C)C2)c2c(C)noc2n1 +Nc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1N +Nc1cccc2c1nc(-c1ccc(F)c(F)c1F)n2CCO +Cc1occc1C(=O)Nc1cc(F)cc(N2CCCC2)c1 +O=C(NCC1CN2CCCCC2CO1)NC(CO)c1ccco1 +COc1cccc(CCNC(=O)c2n[nH]c3ccc(C)cc23)c1 +Cc1cccc(S(=O)(=O)N2CCc3c(C)ncnc3C2)c1 +CC(C)C(NC(=O)Nc1cn[nH]c1)c1ccc(F)cc1 +CC(C)(C)CC(=O)N1CCc2nc(-c3ccccc3)ncc2C1 +O=C(C1CCCO1)N1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +O=C(Cc1ccc[nH]1)NCc1ccccc1Cn1cccn1 +CC(C1CC1)N(C)C(=O)NCC1Cc2ccccc2O1 +COc1ccc(NC(=O)N2CCC(c3cc(N)on3)CC2)cc1 +CN(C(=O)CN(c1ccccc1)S(=O)(=O)N(C)C)c1ccccc1 +CC(C)(C)CCOC(=O)C1CCN(c2cnccn2)CC1 +CCC(C)(C#N)NC(=O)Cc1ccc(F)cc1F +CC(C)c1nnnn1CC(=O)Nc1ccc(C(F)(F)F)cc1 +Cc1cc(Oc2ncnc(NCC3CCCO3)c2N)cc(C)c1Cl +O=C(CCNC(=O)c1cnc2c(c1)NC(=O)CO2)Nc1ccccc1 +CCNC(=O)N1CCN(C(=O)c2cccs2)CC1 +CCC(C(=O)Nc1cccc(N)c1)N(CC)c1ccccc1 +Cc1nc(C)c(CC(=O)NC2(c3ccc(Cl)cc3)CCC2)c(=O)[nH]1 +Cc1cc(NC(=O)c2ccccn2)c2ncccc2c1 +CCOc1ccccc1NC(=O)COc1ccc(-c2nnco2)cc1 +O=C(NCc1ccncc1)Nc1ccc2c(c1)Cc1ccccc1-2 +CCC(CNC(=O)CNC(=O)OC)c1ccccc1 +CN(C)c1ccc(C(=O)Nc2ccccc2N2CCOCC2)cc1 +CN1CCN(C(=O)C2CN(C(=O)c3cnccn3)C2)CC1 +O=C(Nc1ccc(NC(=O)c2ccco2)cc1)c1ccc(F)c(F)c1 +CC(C)c1ccsc1C(=O)NCc1ccc(S(N)(=O)=O)cc1 +Cc1c(CNC(=O)Nc2cc(C3CCCCC3)nn2C)cnn1C +CC(C)(C)c1ncc2c(n1)CN(C(=O)c1ccc(-c3nc[nH]n3)cc1)C2 +COCCc1nccc(-c2cn(-c3ccccc3)nc2C)n1 +N#CCSc1sc(C#N)c(N)c1-c1ccccc1 +Cc1noc(CNC(=O)C2CCN(C(=O)c3ccc(=O)[nH]c3)CC2)n1 +O=C(c1cccc2nscc12)N1CCc2ccccc21 +COC(=O)C1CCC2(CCN(C(=O)OC(C)(C)C)CC2)C1O +COCCN1CC2(CCC1=O)CCN(c1nccc(OC)n1)CC2 +Cc1cc(F)ccc1CCNC(=O)Nc1cnccc1C +O=C(CSc1ccncc1)NCc1ccc2c(c1)OCO2 +CC(=O)c1ccc(N2CCN(C(=O)n3ccnc3)CC2)cc1 +CCn1c(C)nnc1Cn1ncc2ccccc2c1=O +Cc1nc(CNc2ncnc3c2cnn3CCO)cs1 +Cc1ccsc1CNC(=O)Nc1c(C)cccc1C +CC(=O)c1cccc(NC(=O)NCc2ccccn2)c1 +CS(=O)(=O)N1CCN(c2ccc(C(N)=O)cc2)CC1 +Cc1cccc(Cn2c(=O)oc3cc(N)ccc32)c1 +N#Cc1c(F)cccc1OCCN1CCOCC1 +CC(C)(C)C(=O)N1CCN(C(=O)Nc2ccncc2)CC1 +CCN(CC)C(=O)CN(C)C(=O)c1c[nH]c2ccccc12 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)C1CC(=O)N(C)C1 +CCCCN(C)c1ccc(C(=O)N2CCOC(C)C2)cc1 +Cc1nn(C)cc1Cn1c(=O)ccc2ccccc21 +CCC(C)c1ccccc1N1CC(C(=O)NCC(N)=O)CC1=O +Cc1ccc(NC(=O)C(C)(C)C)cc1NC(=O)C1CC2CCC1O2 +Cc1noc(CCCC(=O)Nc2ccc(CN3CCCC3=O)cc2)n1 +CSc1nnc(C(=O)Nc2cccc(C#N)c2)n1C +CC1CN(CC2CCCN2C(=O)NCc2ccncc2)CC(C)O1 +CCS(=O)(=O)c1ccc(NC(=O)N(C)Cc2cnn(C)c2)cc1 +Cc1ncc2c(n1)CC1CCC2N1C(=O)COc1ccccc1F +CSc1nnc(SCc2nnc(C3CCCO3)o2)s1 +COc1ccc(Cl)cc1C(=O)N1CCCC1c1nc(C2CC2)no1 +C=CCOCCCC(=O)N1CCc2cc(F)ccc2C1C +O=C(CCCNC(=O)c1cccs1)NC1C2CC3CC(C2)CC1C3 +Cc1cccnc1CNC(=O)NC(C)CCC1CCCC1 +Cc1nnc2n1CCN(CC(=O)N(C)Cc1cnn(C)c1)C2 +COc1cc(OC)cc(C(=O)NCCc2cn(C)c3ncccc23)c1 +O=C(c1ccc(F)cc1)N1CCN(CCO)CC1 +O=C(CSc1ccccc1F)Nc1cccc(-c2cn[nH]c2)c1 +CN(C)C(=O)CCCC(=O)N1CCn2cccc2C1c1ccccc1 +Cc1cccc(-c2nnc(NC(=O)c3ccc4c(c3)OCO4)o2)c1 +Cc1ccc(OCCCC2CCCCN2C(=O)OC(C)(C)C)nn1 +CC(NC(=O)N(C)C(C)c1cc2ccccc2o1)c1nncn1C +Cc1nc(SCC(=O)Nc2ccc(F)cc2)[nH]c(=O)c1C +NC(=O)c1ccc(NCC(=O)N(Cc2ccccc2)C2CC2)cc1 +CC(OC(=O)c1cc(N2CCCC2=O)ccc1Cl)c1cccnc1 +CN(C)c1nc2c(c(=O)[nH]c(=O)n2C)n1CCc1ccccc1 +Cc1nnc(SC(C)C(=O)N2CCOCC2)n1C +CCC(O)c1nc2ccccc2n1CC(=O)N(C)c1ccccc1 +Nc1cccc(CC(=O)OCc2cc(Br)cs2)c1 +Nc1ccc2c(c1)OCCN2C(=O)CCCOc1ccccc1 +Cc1nc2ccc(NC(=O)NCCCOCC3CC3)cc2o1 +COc1cc2c(cc1OC)CN(C(=O)Cc1cccs1)CC2 +Cc1ccc(NC(=O)CCC(=O)c2ccc3c(c2)OCCCO3)cc1 +Cc1cc(C)cc(NC(=O)c2ccccc2S(C)(=O)=O)c1 +CCCn1nnnc1CN1CCCC1Cc1cccc(F)c1 +CCC(O)c1cc(C)ccc1S(=O)(=O)CC(C)C +COc1ccc(N2CCC(C(=O)Nc3ccc(F)cc3)C2=O)cc1 +COc1cc(OC)cc(C(=O)N2CCN(CCO)CC2)c1 +Cc1cccc(NS(C)(=O)=O)c1NS(C)(=O)=O +COc1ccc(NC(=O)CCC(=O)Nc2ccc(F)cc2)c(OC)c1 +O=C(CN1CCC(n2c(=O)[nH]c3ccccc32)CC1)c1ccc[nH]1 +CCCC1(CO)CCCN(C(=O)c2cc(=O)[nH]c3cc(F)ccc23)C1 +O=C(NCc1cscn1)N(Cc1ccccc1)Cc1ccco1 +NC(=O)Nc1cccc(C(=O)OCc2ccccc2F)c1 +C=CCNC(=O)NCc1cccc(NC(=O)C2CCCO2)c1 +COc1ccc(NC(=O)c2c(C)nn3ccccc23)cn1 +CC(Oc1ccccc1)C(=O)Nc1cccc(Cn2cccn2)c1 +CCOc1ncccc1CNc1nc2c(s1)c(C)nn2C +COCCCNC(=O)c1nnn(-c2ccc3ncccc3c2)c1C +Nc1oc(-c2cccnc2)cc1C(=O)C1CCCCC1 +CC(=O)c1csc(NC(=O)CC(C)c2ccccc2)n1 +Cc1cc(C)n(CC(C)CNC(=O)Nc2cn[nH]c2)n1 +Cc1ncc(CNC(=O)c2c(F)cccc2Cl)s1 +Cc1nc(CC(=O)N2CCCC2c2nc3c(C)cccc3[nH]2)cs1 +COc1ccccc1CNC(=O)NCC#Cc1ccccc1 +CC(C)n1c(=O)[nH]c2cc(C(=O)NCC(F)(F)F)ccc2c1=O +Cc1ncc(CNC(=O)C(C)Sc2ccccc2Cl)s1 +Cc1oc(-c2cccs2)nc1C(=O)NC(C(N)=O)c1ccccc1 +Oc1ccc(-n2nnnc2SCC(F)(F)F)cc1 +CCc1ccc(S(=O)(=O)Nc2cnn(CC3CC3)c2)cc1 +Cc1nnnn1-c1cccc(NC(=O)c2ccc(C(C)C)cc2)c1 +CCOc1ccccc1NC(=O)N1CCN(S(=O)(=O)CC)CC1 +CCCS(=O)(=O)NC(C)c1ccccc1OC +CC(=O)c1cccc(NC(C)C(=O)N(CCC#N)c2ccccc2)c1 +CCc1ccccc1NC(=O)N1CC(C(=O)NC)C2(CCCC2)C1 +CC1(C)CCN(C(=O)Cc2c(F)cccc2F)C1 +Cc1cc(CNC(=O)CCCNC(=O)c2ccc(Cl)cc2)c(C)o1 +CCCC1CN(C(=O)CCC2CCN(C(C)=O)CC2)CCO1 +NC(=O)c1csc(CNc2nc3cc(Cl)ccc3o2)c1 +O=C(CCc1ccncc1)N1CCCCC1CCN1CCOCC1 +COc1ccc(-n2c(=O)oc3ccc(Cl)cc3c2=O)cc1 +CC(C)CCCCNC(=O)Cn1ccc(=O)n(C)c1=O +CC1CC(C)CN(C(=O)c2ccc(N3CCCC3=O)cc2)C1 +CCn1cc(NC(=O)CNc2cc(Cl)ccc2OC)ccc1=O +O=C(COCC1CCCO1)Nc1ccccc1Oc1ccccc1 +Cc1noc(C)c1S(=O)(=O)N(C)CC(=O)NC1CCCCCC1 +CS(=O)(=O)N1CC(c2nc3ccccc3[nH]2)C1 +CC1COCC(C)N1CCOCCOc1ccccc1 +C#CCNC(=O)N(C)CCCOc1cccc(S(C)(=O)=O)c1 +CC(C)Oc1ccccc1CC(=O)N(C)CC(=O)NC(C)(C)C +CC(C)(C)c1noc(CCC(=O)NCCCO)n1 +O=C(OCc1ccccc1)N1CC(O)CC1CO +O=c1oc2cc(CO)ccc2n1CCN1CCOCC1 +CC(=O)c1cc(Br)cc(CCNC(=O)OC(C)(C)C)n1 +COc1cc(C)c(S(=O)(=O)CCC#N)cc1C +Cc1ccccc1CC(C)NC(=O)Cn1nnc(-c2ccccc2C)n1 +CN(C)C(=O)CSc1nnc(-c2cccc3ccccc23)o1 +Cc1cc(NCc2cccnc2)n2ncc(-c3ccccc3)c2n1 +O=C(OC1CCOC1)c1ccc(F)c(Br)c1 +Nc1nnc(SCC(=O)N(C2CCCC2)C2CC2)n1C1CC1 +NC(=O)CNC(=O)c1cc2cc(Cl)ccc2o1 +Cc1cc(C)cc(C(=O)N2CC(c3nc(-c4ccccc4)no3)C2)c1 +N#CCCC(C#N)CN1CCN(C(=O)c2ccco2)CC1 +NC(=O)c1ccccc1OS(=O)(=O)c1cccc(Cl)c1 +CSc1cccc(NC(=O)CNC(=O)C2CCCCC2)c1 +COCCN(CC(F)(F)F)C(=O)c1cc2cc(Cl)ccc2o1 +CCNc1ccc(Cl)c(C(=O)NC(C)C(=O)NC)n1 +CC(C)CC(N1CCOCC1)n1nnc2ccccc21 +CC(C)(C)C(NC(=O)Cc1coc(-c2ccc(Cl)cc2)n1)C(N)=O +CNC(=O)c1cccc(NC(=O)C(C)Oc2c(C)cccc2C)c1 +N#Cc1nccnc1NCCc1nc(-c2ccco2)n[nH]1 +CCOC(=O)c1cc2c([nH]c1=O)CC(c1ccc(C)s1)CC2=O +CN(C)C(=O)c1cccnc1CC1COc2ccccc2C1 +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1ccco1 +Cc1ccccc1N1CCN(C(=O)c2ccoc2C)CC1 +CCCCNC(=O)c1cc(S(=O)(=O)NC(C)C)ccc1Cl +OC1COCCN(c2ncnc3c2Cc2ccccc2OC3)C1 +O=C(c1c(F)cccc1F)N1CCC(c2n[nH]c3nccnc23)CC1 +Nc1nc(CCc2ccccc2)ncc1C(=O)NC1CCCC1 +Cc1ccn(CCC(=O)Nc2cccc3cc(C)oc23)n1 +CNC(=O)CN(C)C(=O)c1cc(-c2ccccc2OC)on1 +Cc1nc2ccc(C(=O)N3CC(c4ccccn4)C3)cc2nc1C +COc1ccc(S(=O)(=O)NCc2ncoc2C)cc1C +COc1ccc(C(O)CN2CC(C)OC(C)C2)c(OC)c1 +COc1ccc(CC(=O)c2c[nH]c3ccc(OC)cc23)cc1 +Cc1sc2ncnc(NC3CCCc4c3cnn4C)c2c1C +Cc1cc(CNC(=O)CCNC(=O)c2ccco2)c(C)o1 +O=C(NCCc1cn2ccccc2n1)c1cc2cc(F)ccc2s1 +c1ccc(COc2ccc(CSc3nncn3C3CC3)cc2)nc1 +Fc1ccc(NCCCN2CCOCC2)cc1Cl +COC(=O)Cc1ccc(OC(=O)Cc2cccc(F)c2F)cc1 +Cc1cc(C(=O)NC(C)c2ccncc2)c(C)n1Cc1ccccc1 +CCC(=O)Oc1ccc(C(=O)Nc2ccc(O)cc2C)cc1 +CN1CCN(C(=O)Cc2cnc[nH]c2=O)CC12CCNC(=O)CC2 +Cc1ccc(OC2CCN(C(=O)c3ccc(F)cc3F)CC2)cn1 +Cc1ccc2nc(NC(=O)c3ccc(C)[nH]c3=O)sc2c1 +CC(=O)Nc1ccc(OC(=O)c2ccccn2)cc1 +CCOC(=O)C1CCCN(C(=O)c2cc(C)nc3ccccc23)C1 +Cc1cc(=O)oc(C)c1C(=O)OC(C)C(=O)N1CC(C)OC(C)C1 +CC(NC(=O)CSc1nncs1)c1ccccc1Cl +NC(=O)C1CCCN(C(=O)c2c[nH]nc2-c2cccc(Cl)c2)C1 +Cc1nc(C2CC2)ncc1-c1nc(C2CCOC2)no1 +COc1ccc(OCCCOc2cc(N)ccc2C)cc1 +O=C(Nc1ccc(Br)cc1)Nc1cccnc1 +CC(C)C(=O)c1ccccc1NC(=O)c1ccc(C#N)cc1 +COCCN1CCN(C(=O)NCc2csc(C(C)C)n2)CC1=O +CN(CCc1cnccn1)C(=O)NCc1ccco1 +O=C(NCc1ccco1)Nc1nnc(Cc2ccc(F)cc2)s1 +CC(=O)NCc1ccc(C(=O)NCCNC(=O)c2cccnc2)cc1 +CCOc1ccc(-c2cnn(C)c(=O)c2CO)cc1CC +O=C(c1cc(Cl)c[nH]1)N1CCN(c2nccs2)CC1 +CNc1snc(C)c1C(=O)NC1CCc2ccccc21 +OCC1CN(c2ccc(Cl)cc2)C(c2ccc(O)cc2)O1 +COc1cccc(CO)c1OCC(=O)N1CCOCC1 +Cc1ccccc1Nc1nc(N)nc(CSc2cc(C#N)ccn2)n1 +CCCCCNC(=O)c1onc(-c2ccc(F)cc2)c1N +Cc1ccc(OCC(=O)NC2CCCCCC2)cn1 +CN(CC1CC1)C(=O)CNS(=O)(=O)c1cn(C)cn1 +O=C(CNS(=O)(=O)c1cccs1)Nc1cc(F)cc(F)c1 +COC(=O)C1(NC(=O)C2CCN(c3cnccn3)CC2)CCCC1 +Cc1cc(Br)ccc1NC(=O)Cn1ccnc1 +O=C(NCCc1ccncc1)c1c(-c2ccccc2)nn2ncccc12 +C=CCNS(=O)(=O)c1cccc(C(=O)NCc2c[nH]cn2)c1 +COC(=O)Cn1c(=O)n(CCC(C)C)c(=O)c2ccccc21 +O=C(c1ccc(N2CCC3(CC2)OCCCC3O)nc1)N1CCCC1 +COC(C)(C)c1noc(COc2ccc3c(c2)CCC(=O)N3)n1 +CC(C)c1nc(CN(C)C(=O)c2cn3cccnc3n2)no1 +COCCn1cc(NC(=O)c2ccc(=O)n(C)n2)cn1 +COc1ccc(OC)c(-c2oc3ccccc3c(=O)c2OC(C)=O)c1 +CC(C)Nc1cccc(CNC(=O)Cc2cc3ccccc3[nH]c2=O)c1 +COC(=O)Cc1csc(NC(=O)Nc2c[nH]nc2C)n1 +COC(=O)C(C)NC(=O)c1cc(N)cn1C(C)C +CCC1C(=O)NCCN1Cc1cc(F)cc(F)c1 +Cc1cc(N2CCN(c3ccccc3)CC2)n2nnnc2n1 +CN1CCN(S(=O)(=O)Cc2ccc(Br)cc2)CC1 +COC(=O)C(NC(=O)c1cc2cc(F)ccc2[nH]1)C(C)C +Cc1nc2c(c(=O)n1CC(=O)NCCCc1ccccc1)CCCC2 +CS(=O)(=O)c1ccc(N2CCCOCC2)c(N)c1 +CCn1cc(SCC(=O)N2CCOCC2)c2ccccc21 +COCCN1CCOCC12CCN(C(=O)c1c(C)noc1C)CC2 +N#Cc1ccccc1NC(=O)CCSc1nnnn1C1CC1 +CC(Sc1nc2sccc2c(=O)n1C)C(=O)N(C)CCC#N +C#CCOc1ccc(F)cc1NCc1noc(C(C)C)n1 +Cc1ccc(C(CNC(=O)C2CC=CCC2)N2CCOCC2)o1 +Cc1ccc(C2NC(=O)NC3=C2C(=O)N(CCO)C3)cc1 +COc1ccc(-c2n[nH]cc2C(=O)NCc2cccc(OC)c2)cc1 +O=C(c1cccc(Cl)c1)N1CCCC1CCCO +CNc1ccc(Cl)c(C(=O)NCCCC(N)=O)n1 +COc1cccc2cc(C(=O)NC(C)c3ccncc3)oc12 +COc1cccc2cc(C#N)c(N3CCC(=O)CC3)nc12 +O=C(c1ccc2ccccc2n1)N1CCN(Cc2ccncc2)CC1 +COc1ccc(OC)c(C(=O)CC2(O)C(=O)Nc3ccc(F)cc32)c1 +CCOc1ccc(-c2nc(C(=O)N(C)CC)cs2)cc1OC +Cc1cnn(CC2CN(Cc3nnnn3C3CC3)CCO2)c1 +COc1ccc(Cl)cc1NC(=O)c1cc(=O)[nH]c2ccccc12 +CC(CCCO)NC(=O)NCCc1nc2ccccc2s1 +Cc1nc(SC(C)c2cn(-c3ccccc3)nn2)oc1C +Cc1ccc(CN2CC(C)OC(c3ccc(F)cc3)C2)o1 +O=C(NCc1ccsc1)N1CCc2ccccc21 +CCOC(=O)c1cnn(Cc2ccccc2Cl)c1N +CCC(=O)N1CCC2(CC1)c1nc[nH]c1CCN2S(C)(=O)=O +Cc1cccc(NC(=O)Nc2cc(N)ccc2F)c1 +COc1ccc2nc(C)c(C(=O)NCc3ccc(OC)nc3)cc2c1 +COCCCCCNC(=O)Nc1ccc2oc(=O)ccc2c1 +CNC(=O)Nc1cccc(-c2nnc3n2CCC3)c1 +CCCC1CC1NC(=O)C(C)Sc1ccccn1 +COc1ccccc1CN(C)C(=O)Nc1cccnc1 +Cc1ccc(S(=O)(=O)CC(C)C)c(CCO)c1 +Nc1ccn(CCCCOc2ccccc2Cl)n1 +Cc1nn(C)cc1S(=O)(=O)NCCN1CCOCC1 +Cc1cc(NC(=O)c2ccc(OC(F)(F)F)cc2)n(C)n1 +Cn1c(CCNC(=O)c2cc3n(n2)CCS3)nc2ccccc21 +Clc1cccc(OCc2noc(C3CC3)n2)c1Cl +CCOCC1CCCN1C(=O)c1cccnc1NC +N#Cc1cccnc1Oc1ccccc1NCc1cccc(C(N)=O)c1 +CNS(=O)(=O)c1cccc(C(=O)NC2CCOC(C)(C)C2)c1 +CCOc1c(Br)cc(CNc2ncn[nH]2)cc1OC +CCc1ncc(C(=O)NCCCN2CCOCC2)c(N)n1 +CC(C)COc1ccccc1NCc1nc(C2CC2)no1 +Cc1cccc(C(=O)NCC#Cc2ccc(N(C)C)cc2)c1 +Cc1onc(-c2ccccc2)c1C(=O)N1CCCC1 +O=C(Cn1ccc(=O)[nH]c1=O)Oc1ccc(Cl)c2ccccc12 +Nc1nc(COC(=O)c2ccsc2)nc(Nc2ccccc2)n1 +CCC1c2ccccc2CCN1C(=O)Cc1ccc(C)nc1 +Cc1nn(C)c(C)c1C(=O)N(C)Cc1ccc(F)c(F)c1 +O=C(COC(=O)C1CCCC1)c1ccc(O)cc1O +CC(C)NC1C(=O)Nc2cccc(Br)c21 +N#Cc1cccc(-c2nnc(-c3cccc(N)c3)o2)c1 +CCC(C)C(=O)NC(C(=O)OC)c1ccc(Cl)c(F)c1 +COC(=O)C1CN(Cc2c[nH]nc2C(C)(C)C)CCO1 +CNC(=O)c1cc(S(=O)(=O)N2CCCC(C)C2)ccc1OC +O=C(CC1C(=O)Nc2ncnn21)Nc1cccc(OC(F)(F)F)c1 +CCOC(=O)C1=C(CNc2c(F)cc(F)cc2F)NC(=O)NC1C +CC1Cc2ccccc2N1Cc1cc(C#N)cs1 +CCn1cnnc1CNC(=O)c1cc(Br)ccc1F +COCc1ccccc1NC(=O)NCCc1c[nH]c2cc(F)ccc12 +CN(C(=O)c1cn(C)c2ccccc12)C1CCCC1 +COc1ccc2ccccc2c1CNn1nnnc1N +Cc1ccc(CN(Cc2ccco2)C(=O)NCc2ccccn2)s1 +O=C(CNC(=O)c1n[nH]c2cc(Cl)ccc12)NCc1cccs1 +Cc1ccc(CC(=O)Nc2ccccc2N2CC(C)OC(C)C2)cn1 +COc1ccc(C(=O)Nc2ccccc2)cc1OC +CCOC(=O)CN1CCN(CC(F)(F)F)CC1 +COC(=O)CCn1cnc2scc(-c3ccc(C)c(C)c3)c2c1=O +CC1CCN(C(=O)Cc2ccc(S(=O)(=O)C(F)F)cc2)CC1 +O=C(c1cnccn1)N(Cc1cnc2ccccn12)C1CC1 +CC(=O)c1cccc(NC(=O)Nc2cnn(Cc3ccccc3C)c2)c1 +COc1ccc(OC(=O)c2cccnc2N(C)C)cc1 +CC1CCCCC1CNC(=O)c1ccnc(F)c1 +Cc1cc(CN(C)Cc2noc(Cc3ccccc3)n2)no1 +COc1cccc(OCc2nnc3c(N)ccc(C)n23)c1 +O=C(N1CCCC(CO)C1)C1(c2cccc(F)c2)CCOCC1 +CCCCNC(=O)CCc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +O=C(CC1(O)CCCCC1)Nc1cccc(S(=O)(=O)C(F)F)c1 +Cc1cccc(-c2cncc(C(=O)N3CCCCC3)c2)c1C +CN(CC1CC1)C(=O)c1ccc(NC(=O)OC(C)(C)C)cc1O +CN(C)C(=O)Sc1ccccc1NC(=O)c1cc(F)ccc1F +O=C(NCCOCC1CCCO1)NCc1cc(=O)[nH]c2ccccc12 +Cc1ccc(C(N)C(=O)NCc2ccccn2)cc1 +CCOC(=O)C(CC)n1c(N)nc2cc(F)c(F)cc21 +Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)N(C)Cc1ccccc1 +Cc1nn(CC(=O)c2ccc(F)c(F)c2)c(C)c1Br +Cc1ccc(-n2nnnc2SCC(=O)C(C)(C)C)cc1 +CC(C)(C)n1ncc2c(=O)n(NC(=O)CCc3ccccc3)cnc21 +Cc1cnc(CCNC(=O)COc2ccccc2)s1 +C=CCOc1ccc(CNc2nccs2)cc1OC +COc1ccc(N)cc1-n1cc(-c2ccc(Cl)c(C)c2)nn1 +COc1ccc2c(c1)OCC(C(=O)NCCNC(C)=O)C2 +CCC(C(=O)Nc1ncc(C#N)s1)c1ccccc1 +CC1CCCC(CNC(=O)C(C)Sc2nncn2C)C1 +Cc1ccnc(NC(=O)CN(C)c2ccc3nnc(C)n3n2)c1 +CC(=O)N1CCN(CC(=O)Nc2nc(C)cs2)CC1 +CC(Oc1ccccc1)C(=O)N1CCN(CC(=O)c2ccco2)CC1 +Cc1cc2c(cc1C)N(CCCO)C(=O)C(C(C)C)N2 +O=C(Nc1ccccc1C(=O)N1CCCCC1)c1ccccc1Cl +CNC(=O)C1CCN(S(=O)(=O)c2ccc(C(C)(C)C)cc2)CC1 +COc1ccc(COC2CN(C(=O)c3cccc(F)c3)C2)cc1F +Cc1ccc(N2CCCC2=O)c(C(=O)N2CCC(O)C2)c1 +Fc1ccc(-c2nc(CSc3nncn3C3CC3)co2)cc1F +O=C(C1CCC1)N1CC2CCC(C1)N(C(=O)c1ccon1)C2 +CC(=O)NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1 +CC(C)(C)CC(C)(C)NC(=O)c1ccc(C(N)=O)cc1 +c1cncc(CC2C(OCC3CC3)CCN2Cc2ccncc2)c1 +Cc1ccc(C(C)NC(=O)N2CCC(NS(C)(=O)=O)CC2)o1 +Cn1cnnc1C1CCN(C(=O)Cc2csc3ccccc23)CC1 +Cc1cc(C)cc(N2CCC(NC(=O)c3ccsc3)C2=O)c1 +C#CCN1CCN(C(=O)NCCCn2nc(C)cc2C)CC1 +COc1cc(NC(=O)c2n[nH]cc2Cl)c(OC)cc1Cl +COc1ncccc1CNC(=O)C1CC(=O)N(C)C1 +O=C(c1cccnc1-n1cncn1)N1CCN(CC(F)(F)F)CC1 +Cc1cc(C(=O)NCC(=O)NC(C#N)c2cccc(Cl)c2)c(C)o1 +C=CCN(Cc1cc(-c2cccs2)on1)S(=O)(=O)C(C)(C)C +Cc1cc(-c2cnc(C(C)C)nc2CCNC(=O)C2CC2)on1 +CNS(=O)(=O)c1cccc(NC(=O)C(C)(C)C#N)c1 +CN(C)C(=O)COc1cccc(NC(=O)CN(C)c2ccccc2)c1 +Cc1ccc(C2CCCN2S(=O)(=O)C2CCOC2)o1 +Cc1ccc(CN2CC(c3noc(-c4ccncc4)n3)CC2=O)cc1 +Cc1ccc(Cn2ncc3ccccc3c2=O)cc1 +CCN(CCO)C(=O)C1CCN(CC(F)(F)F)CC1 +COCC(=O)NC1CC(=O)N(Cc2cccc(F)c2)C1 +Cc1cc(C(=O)NCc2ccnc(OC(C)(C)C)c2)[nH]c(=O)n1 +NC(=O)c1cccc(NC(=O)CCCNC(=O)c2ccc(F)cc2)c1 +COCC(NC(=O)c1cc(F)ccc1O)C(N)=O +Cc1cc2c(N)cccc2c(C(=O)N2CCOCC2)n1 +CC(Nc1ccc(Cl)cc1)c1cccc(-n2cnnn2)c1 +Cc1ccc(NC(=O)Cn2nnc3c(C)n(C)nc3c2=O)cc1 +O=c1c2cnc3ncnn3c2ccn1-c1ccc(O)cc1 +O=C(Nc1nc2c(Cl)ccc(Cl)c2s1)c1cnccn1 +CCS(=O)(=O)NCCN1CCN(c2ccc(Cl)cn2)CC1 +CC(C)Cc1noc(-c2ccc(N3CCCC(O)C3)nc2)n1 +Brc1ccc(CN2CCN(c3ncccn3)CC2)cc1 +c1cc2[nH]c(C3CCOC3)nc2cc1-n1cnnn1 +COc1ccc(N(C(C)=O)S(=O)(=O)c2cccs2)cc1 +NC(c1ccc(F)cc1Br)C(F)(F)F +Cc1c(C(=O)NCCc2ccccn2)oc2c(F)cccc12 +O=C(Cn1cnc(C2CCC2)cc1=O)c1ccc(OC(F)F)cc1 +CC(=O)Nc1nc(C(=O)Nc2nc3c(C)cc(C)cc3s2)cs1 +N#CCc1ccc(NC(=O)Nc2ccc3c(c2)CC(=O)N3)cc1 +Cc1cc(F)ccc1CN1CCN(c2ccc3nnc(C)n3n2)CC1 +O=C(Cn1nc2c(cc1=O)CCCC2)Nc1cc(F)c(F)c(F)c1 +O=c1c(Cl)c(N2CCOCC2)cnn1Cc1ccccc1Cl +CC1(C(=O)NCc2ccnc(OC3CCC3)c2)CCCO1 +CCN(Cc1cc2cccc(C)c2[nH]c1=O)C(C)=O +COC(CNS(=O)(=O)C1CCCCC1)c1ccc(C)s1 +CCn1nnc2cc(C(=O)Nc3cccc(Cn4ccnc4)c3)ccc21 +Cc1nc2cc(S(=O)(=O)N3CCC(=O)CC3)ccc2[nH]1 +CN(CC(=O)N(C)C1(C#N)CCC1)C(=O)c1ccccc1 +CN(C)c1nc(N)nc(CSc2nc3ccccc3[nH]c2=O)n1 +CCn1cnnc1CNC(=O)NCc1ccccc1Cn1cccn1 +CCOCC1CCCN(C(=O)Cc2cccs2)C1 +Cc1ccccc1OC1CCN(C(=O)C2CCOCC2)CC1 +C#CCCNC(=O)c1cc(OC)c(OC)c(OC)c1 +CCC(NC(=O)N(C)C(C)c1ccccn1)c1cc(F)ccc1F +O=C(CSc1nc(=O)[nH]c2c1CCC2)NCc1ccc(Cl)cc1 +O=C(CC1CCCC1)Nc1cnn(-c2ccccc2F)c1 +CCn1nc(C)c(CN2CCc3nc(C(C)C)[nH]c(=O)c3CC2)c1C +CC(=O)Nc1cc(NCc2cnnn2C)ccc1Cl +COCc1cc(C(=O)N2CCCC(c3ccn[nH]3)C2)ccc1F +O=C(NCC(=O)N1CCc2ccccc21)c1cnc2cccnn2c1=O +O=C1CC2(CCN(C(=O)c3ccc(F)c(F)c3)C2)Oc2ccccc21 +N#Cc1ccc2ccn(CC(=O)NCc3ccccc3)c2c1 +CCOC(=O)c1nccnc1C(=O)Nc1ccc(F)cc1 +Nc1cncc(S(=O)(=O)N2CCCCCC2)c1 +COc1ccccc1CN(Cc1cccnc1)C(=O)c1ccsc1 +Cc1cccc(OC(C)C(=O)Nc2ccc(NC(N)=O)cc2)c1 +Cc1noc(C)c1S(=O)(=O)Nc1ccccc1O +CN(C)C(=O)CSc1nc2ccccc2c(=O)[nH]1 +CCN(CCNS(N)(=O)=O)c1cccc(C)c1 +CC(C)C(=O)N1CCOC2(COCCN(c3ncccn3)C2)C1 +CCc1nnc(CSc2nc3ccccc3s2)o1 +COc1ccc(C(NC(=O)CCn2cccn2)C2CCOCC2)cc1 +COCCN(C(=O)c1ccc2c(=O)n(C)c(=O)n(C)c2n1)C1CC1 +COCC(=O)N1CCN(CC(=O)NC(c2ccccc2)C2CC2)CC1 +Cc1nnsc1C(=O)NC1CC2(CCCC2)Oc2ccccc21 +CCNC(=O)C(C)NC(=O)c1c[nH]cc1-c1ccccc1OC +N#Cc1ccc(NC(=O)c2noc3c2CCCCC3)cc1 +COC(=O)c1ccc(NCCOC2CCCC2)nn1 +CN(C)c1nc(NCCCn2nnc3ccccc32)ncc1F +CC(C)(C)C(C#N)NC(=O)c1ccc(S(=O)(=O)CCCC#N)cc1 +CCc1nnc(NC(=O)Cn2nc3c(cc2=O)CCCCC3)s1 +Cc1cc(NC(=O)NC(c2noc(C)n2)c2ccccc2F)sn1 +Cn1c(Nc2cccc(C(F)(F)F)c2)cc(=O)n(C)c1=O +Cc1cc(NC(=O)CNc2ccc(-n3cnnn3)c(C)c2)no1 +O=C(CN1C(=O)COc2ccccc21)N1CCC2CCCCC2C1 +CCc1ccccc1NC(=O)CN(C)C(=O)c1ccccc1C +O=S(=O)(Nc1nnc(C2CC2)s1)c1cccc2nonc12 +CC(C)CN(CC(C)C)c1c(Cl)cn[nH]c1=O +CC(C)N(C)S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +Cc1nnnn1C(Cc1ccc(F)cc1)C(=O)Nc1cn[nH]c1 +O=C1CC(C(=O)N(Cc2ccsc2)C2CCCC2)CN1C1CC1 +CSc1nc(C(=O)Nc2ncc(C)s2)c2ccccn12 +CCC(C)NS(=O)(=O)c1csc(C(N)=O)c1 +CC(C)C(Sc1nnnn1CC(F)(F)F)C(=O)N(C)C +Nc1cc(C(=O)NCC2CC=CCC2)c(Br)cc1F +COc1cccc(F)c1-c1nc2ccc(N)cc2[nH]1 +Cc1c(O)ccc(C(=O)Cc2ccc3c(c2)OCCCO3)c1O +Cc1cc(C)c(CNC(=O)c2c[nH]cc2-c2ccccc2)c(=O)[nH]1 +O=C(OCCC(F)(F)F)c1cc(N2CCCC2=O)ccc1Cl +CCCn1nnnc1CN1CCN(Cc2ccccc2)C(C#N)C1 +CC(Cc1c(Cl)cccc1Cl)NC(=O)CCn1cccn1 +CNC(=O)COc1ccc(C(=O)NCC2CC=CCC2)cc1OC +Cc1nc(CNc2cc(C(=O)N(C)C(C)C)ccc2Cl)no1 +CCc1nnc(NC(=O)C2CC(=O)N(c3ccccc3CC)C2)s1 +COc1ccc(C)cc1C(C)(O)CNCc1cccnc1 +O=C(c1ccc(F)cc1)N1CC=C(c2c[nH]c3ccccc23)CC1 +C=CCNc1ccccc1C(=O)N(C)Cc1nc(-c2ccncc2)no1 +COc1ccccc1OCC(=O)NC1CC(=O)N(C(C)(C)C)C1 +Cc1ccc(S(=O)(=O)N(C)CCOc2ccccc2F)cc1 +COc1cn(CC(=O)Nc2cccc(NC(C)=O)c2)c(CO)cc1=O +COc1cc(-c2nc3n(n2)CCC(C)C3)ccc1O +Cc1cccc(CCC(=O)C(C#N)c2nc3ccccc3[nH]2)c1 +CCCNC(=O)CCNC(=O)NC1CCC(O)CC1 +Cc1cccc(N)c1S(=O)(=O)N(C)Cc1ccco1 +CCC1COCCN1S(=O)(=O)c1cn(C)cn1 +CCc1n[nH]c2c1CN(c1nc(C)nc3c1cnn3C)CC2 +Oc1ccc2c(c1Br)C(c1ccco1)NCC2 +O=C(COc1ccccc1O)NCCCc1cccc(F)c1 +Nc1cccc(NC(=O)OCCc2cccs2)c1 +CCCOc1cc(CN2CCOCC2CC)ccc1OC +COC(=O)c1ccc(-n2nc3ccc(N)c(Br)c3n2)cc1 +C=CCNC(=O)NC(C)c1cnc(N(C)C2CCCCC2)nc1C +O=C(CN1CCN(C(=O)COc2ccc(F)cc2)CC1)c1ccco1 +Cc1csc(NC(=O)N(Cc2ccc(C)o2)C(C)C)n1 +CC(C)(CNS(=O)(=O)c1ccc(F)c(C#N)c1)c1ccncc1 +CCOc1cc(C(=O)NC2CCCCCC2)ccc1N +Cc1noc(C)c1COC(=O)Cc1c(C)nc2ccccc2c1C +Cc1cccc(S(=O)(=O)N2CC3CCC2C3Oc2cccnc2)c1 +CC1CCCCC1Nc1c(C#N)c(=O)n(C)c(=O)n1C +CC1(C)Cc2c(cnn2-c2cccc(F)c2)C(NC(=O)CC2CC2)C1 +COc1ccc(NC(=O)NCCCn2ncccc2=O)cc1 +Cc1cnc(CCNCc2ccc(F)cc2C)s1 +CCCN(C(=O)c1c(C)oc2ncn(C)c(=O)c12)c1ccc(F)cc1 +CCC(C)NC(=O)COc1ccc(Cl)c(C)c1 +O=C(CCc1ccsc1)N1CCN(CCO)CC1 +Cc1ccc(CNC(=O)N2CCN(Cc3cccs3)CC2)n1C +COc1cc(CNC(=O)NC(C)CCC(C)C)ccn1 +NC(=O)CC1CCN(C(=O)Nc2nnc(-c3ccccn3)s2)CC1 +Cn1cc(NC(=O)NCC2(c3ccccc3)CCOCC2)cn1 +CCOc1ccc(C(C#N)N2CCC(=O)CC2)cc1 +O=c1c2ccccc2nc(Cc2ccccc2)n1N1CCOCC1 +CN(Cc1nccn1C(F)F)C(=O)NCc1ccc(Cl)cc1 +COc1cc(N)c(NC(=O)Nc2ccccc2)cc1OC +CCC(C)CSc1nnnn1-c1ccccc1OC +O=C(CSc1nc(=O)n2ccccc2n1)NCc1ccc(F)cc1 +NC(=O)c1ccc(NC(=O)C2(c3cccc(F)c3)CCOCC2)cc1 +CNC(=O)c1ccc(NC(=O)c2cc3c(C)cc(C)cc3[nH]2)cc1 +O=S(=O)(NCc1ccc(OC2CCCC2)nc1)c1cccs1 +CCCCC(=O)Nc1cc(OC)c(OC)cc1C +Cc1ccc(N2CC(C(=O)NCc3ccco3)CC2=O)cc1C +O=C1CCc2cc(OC(=O)CCSc3ccccc3F)ccc2N1 +Cc1cc(NCC(O)c2ccccn2)n2nc(C)c(C)c2n1 +CC(C)NC(=O)c1cccc(-n2cnc3cccnc32)c1 +COC(=O)c1cc2c(=O)n(CCO)ccc2nc1C +CC(O)CN(c1ccccc1)S(=O)(=O)c1ccc(F)cc1 +CCOc1ncccc1CNC(=O)NCCC(=O)N1CCCC1 +N#Cc1sc2nc(N)c(C#N)c(-c3ccccc3)c2c1N +COCCOCC(=O)N1CCCCCC1c1ccco1 +CCC(NS(=O)(=O)c1ccc(C)cc1N)C(C)C +COc1cccc(CSc2nnc(Cc3csc(C)n3)o2)c1 +Cc1cc(C)c(OCC(=O)NCCCn2nc(C)cc2C)c(C)c1 +C#Cc1cccc(NCC(=O)N2CCC(C)CC2)c1 +Cc1ccc(NC(=O)CN(C)C(=O)Cc2ccc[nH]2)cc1 +Cc1cccc(NC(=O)c2csc(-c3ccccc3)n2)n1 +CC(C)CC(NC(N)=O)C(=O)NCCc1nnc2ccccn12 +O=S(=O)(NCC1CCCO1)c1ccc(Cl)c(Cl)c1 +CCOc1cc(CO)cc2c1OC(C)(C)C(=O)N2 +Cc1ccc2nc(C(=O)N3CCCC3c3cc(C(C)C)on3)cn2c1 +Cc1cc(OCC(=O)N(C)CC(=O)NC(C)(C)C)ccc1Cl +COc1cc(C)c(NC(=O)CNC(=O)c2cccs2)cc1OC +C#CCNC(=O)CCNS(=O)(=O)c1ccc(C(C)C)cc1 +Cc1ccc(C(=O)CCC(=O)Oc2ccc3c(c2)CCC(=O)N3)s1 +N#Cc1ccc(OCCn2nc(-c3ccco3)oc2=O)cc1 +CCOc1ccccc1OC(=O)COc1ccccc1C +Cc1cc(CC(C)NC(=O)C2(c3ccccc3F)CC2)[nH]n1 +NC(=O)c1ccccc1NCC(=O)Nc1cccc(C(F)(F)F)c1 +O=C(c1ccncc1)N(CC(F)(F)F)C1CCOCC1 +Cc1nccn1CCN1CCN(CC(N)=O)CC1 +CCC(C)(CNC(=O)c1ccc(C)nc1)N1CCOCC1 +CCC1(CC)Oc2ccccc2N(CCCO)C1=O +COc1ccc(Cn2nc(-c3cnn(C)c3)cc2-c2cnn(C)c2)cc1 +O=C(CNC(=O)c1cccc2ccoc12)NC1CC1 +COCc1cccc(C(=O)Nc2ccc(F)c(F)c2)c1 +O=C(CN1CCN(c2ccc(F)cc2)CC1)c1cccs1 +CCC1CCCCN1C(=O)c1cc(OC)ccc1O +COc1ccc(OCCn2c(NC(C)=O)nc3ccccc32)cc1 +CCCCNC(=O)c1cnc(C(C)(C)C)nc1N +CCCCn1cc(C(=O)NCc2ccccn2)c2cccnc21 +CCC(C)n1nccc1NC(=O)Cc1ccc(C)nc1 +COCCNC(=O)c1coc(NC(=O)c2ccccc2)n1 +COC(=O)C(C)CN(C)C(=O)c1cc(C)oc1C +O=C(CCNS(=O)(=O)c1cccc2nonc12)NC1CCCC1 +CCCOc1ccc(C(=O)Nc2ccc3c(c2)OCO3)cc1OC +CC(Sc1nncn1C)C(=O)OC1CCCCC1 +Cc1cc(C(=O)N2CCN(c3ccc(O)cc3)CC2)no1 +O=C(Cn1cccn1)N(c1cccc2cccnc12)C1CCCC1 +COc1ccc(C(=O)N(CCC#N)C(C)C)cc1Br +O=C(Nc1ccn(-c2ncccc2Cl)n1)NC1CCC(CO)CC1 +CCC(C)NC(=O)NCc1ccc(C(=O)N(C)C)cc1 +CC(C(=O)N1CCN(Cc2ccccc2)CC1)c1ccsc1 +CCCNC(=O)CCNC(=O)N1CC(=O)Nc2ccccc21 +CC(C)(O)CCc1cccc(C(=O)N2CCCC2C(N)=O)c1 +CCN(C)C(=O)NCCc1cccc(C(=O)NC)c1 +O=C(Cc1ccc(O)cc1Cl)N1CCc2cc(F)ccc2C1 +O=C(c1ccccc1F)N(Cc1ccccn1)C1CC1 +CC(NC(=O)C(C)(C)C)C(=O)Nc1cccc(C#N)c1 +COc1cc(C(=O)NC2CC(=O)N(C)C2)ccc1OC1CCCC1 +Cc1cc2nnc(SCC(=O)NC3CC3)n2c2ccccc12 +O=C(Nc1cccc(N2CCCC2=O)c1)c1cc2ccccc2c(=O)[nH]1 +Cc1ccc(Cc2nnc(NC(=O)C(C)C)o2)cc1 +CCOc1cccc(-c2cc(CO)c(C3CC3)o2)c1 +Cc1noc(C)c1COc1ccc(CC(=O)Nc2nccs2)cc1 +C#CCCOC(=O)c1cc(NC(C)=O)cc(NC(C)=O)c1 +CC(=O)Nc1cccc(NC(=O)c2cccc(C)n2)c1 +Cc1cccc(-c2cccc(CNC(=O)NCc3ncn(C)n3)c2)c1 +CCOc1ncccc1C(=O)OCC(=O)Nc1ccc(F)cc1F +COCC(NC(=O)c1cnn(-c2ccccc2)c1)C(N)=O +Cc1cc(-c2noc(-c3cn[nH]c3N)n2)ccc1F +O=C(NCc1nnc2n1CCCCC2)Nc1cc(Cl)ccc1F +CN(Cc1nc2c(s1)CCCC2)Cc1cccc2[nH]ccc12 +Cc1cnn(CCC(=O)NCc2ccccc2CN2CCCC2=O)c1 +CC(C)Oc1ccc(CCC(=O)N(C)C)cc1N +C(=Cc1nnnn1Cc1csc(C2CCCO2)n1)c1ccccc1 +NC(=O)CC1CCN(C(=O)c2ccc(O)cc2)CC1 +O=S(=O)(NC1(c2cccc(Cl)c2)CC1)N1CCOCC1 +CCCc1noc(CN2CCN(c3ccccc3F)CC2)n1 +CN(C)C(=O)CCCn1ccc(NC(=O)N2CC3C(C2)C3(C)C)n1 +COc1ccc(CNC2COc3ccccc3C2)c(F)c1 +C=CC1OC2OC(C)(C)OC2C1C(=O)Oc1ccccc1 +COc1ccccc1OCC(=O)N1CCN(C)CC1c1ccccc1 +Cc1cc(C(=O)Nc2ccc(Cc3nnc4ccccn34)cc2)on1 +Cc1nc(COc2ccc3ccc(=O)oc3c2)no1 +CN(CC(=O)NC1CC1)C(=O)c1ccc(C(N)=O)nc1 +O=C1NC2(CCCCCC2)N=C1c1ccc(F)cc1 +Cc1cc(C)c2c(c1)C(O)C(N1CCN(CCO)CC1)CO2 +CC(C)(C)c1nc(CC(=O)N2CCCC2Cn2cccn2)cs1 +Cc1ccc(C)c(NC(=O)C2CC(=O)N(C(C)C)C2)c1 +N#Cc1ccc(COC(=O)C2CC(=O)N(Cc3ccco3)C2)cc1 +Cc1nonc1CN(C)C(=O)C1CC2C=CC1C21CC1 +COC(=O)C1(C#N)C(C#N)(C(=O)OC)C1(C#N)C(=O)OC +CCOc1ccc(NC(=O)NCc2ccccc2COC)cc1F +O=c1cc(CNCc2nnc3n2CCCC3)[nH]c2c(F)cccc12 +CCOc1cc2c(cc1CNc1cccc(NC(C)=O)c1)OC(C)C2 +O=C(CC1CCCC1)NCc1nnnn1-c1ccc(F)cc1 +C#CCCOC(=O)c1nn(CC(C)C)c(=O)c2ccccc12 +Cc1ccc(CNC(=O)C2CCC(=O)N2)cc1F +C=C(C)CN(CC)S(=O)(=O)c1cccc(Cl)c1 +COCCc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +CS(=O)(=O)c1ccc2c(c1)-c1ccccc1C2=O +COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cccc(F)c2)c1 +CC1CCC(N(C(=O)CSc2nnc(N)n2C2CC2)C2CC2)CC1 +CCCc1c(C(=O)NC(C)C)cnn1-c1ccccc1C +COCc1ccccc1CNC(=O)N1C(C)CCCC1C +CCOC(=O)Nc1cc(C)nn1-c1nc(-c2ccco2)cs1 +O=C(NCCN1CCOCC1)c1ccc(OCc2ccccc2)cc1 +CCCCNC(=O)CCC(=O)c1ccc(Cl)c(N)c1 +O=S1(=O)CCCCN1CCCOc1ccc(Cl)cc1 +O=C(CCCNC(=O)c1ccc2cc[nH]c2n1)Nc1ccccc1 +Cc1ccccc1C(C)NC(=O)c1cccc(N)n1 +CCn1cc(NC(=O)NCc2ccc(F)cc2)cn1 +COC(=O)c1cc(CNc2nnc(-c3ccoc3C)o2)c[nH]1 +Cn1ncc2c1C(COCC1CC1)CN(C(=O)c1ccncc1)C2 +O=C1Nc2cc(F)ccc2C1NCC1CCCO1 +Cc1ccc(C(=O)NCC(=O)Nc2ccc(-n3cccn3)cc2)cn1 +C#Cc1cccc(NCC(=O)N2c3ccccc3NC(=O)CC2C)c1 +O=S(=O)(c1ccc(F)cc1Cl)N1CCNCC1 +COc1cc(C#N)ccc1OC(C)C(=O)Nc1sccc1C#N +CC(Cn1cccn1)NS(=O)(=O)c1ccc(F)c(Cl)c1 +CC(=O)N1CCN(C(=O)c2cc3n(n2)CCN(CC2CC2)C3=O)CC1 +CCOc1c(C)cc(C)cc1C(=O)CN1CCOCC1 +CCCCCn1cc(C(=O)NC2CC2)c(=O)c2c(N)cccc21 +Cc1ccc(C(O)c2cc(F)cc3c2NC(=O)C3)cc1 +CC(CCc1ccccc1)NC(=O)Nc1cnn(CC(N)=O)c1 +O=C(c1cnccn1)N1CCc2[nH]nc(-c3ccc(F)cc3)c2CC1 +Cc1ccc2c(c1)C(C)(C)C(=O)N2CC(=O)NCc1cccnc1 +Cn1ncc2c(=O)[nH]c(NCCOc3cccc4ccccc34)nc21 +O=C(NCCN1CCOCC1)c1cnc(N2CCOCC2)nc1 +CCOc1ccc(-n2ncc(C(=O)Nc3cnn(C)c3)c2C)nn1 +O=C1CCCN1CCCSc1nc(C2CC2)nc2ccccc12 +N#Cc1cc(CNc2cc(Cl)ccn2)ccc1F +Cc1ccnc(C2(C)CCCN2C(=O)c2ccc(F)cc2)n1 +Oc1cc2c(cc1F)CCNC2c1cc(F)c(F)c(F)c1 +CN(CC1CN(CC(N)=O)CCO1)c1cccnn1 +CCC(CC)CNC(=O)C(N)c1cc(F)ccc1C +CCN1CCN(C(=O)c2nc(SC)ncc2Cl)CC1 +CNC(=O)COc1ccccc1OCc1ccccc1 +O=C(CCn1ccc2ccccc21)NCc1cccc2cccnc12 +COc1cc(NCc2ccccc2OC)nc(C(C)C)n1 +C#Cc1cccc(NC(=O)CNC(=O)c2cccnc2SC)c1 +CCCCN(CCO)C(=O)c1cc2cc(Cl)ccc2[nH]1 +O=C(Cc1ccc[nH]1)NC1CC1c1ccccc1Br +O=c1[nH]cccc1-c1cc(NCc2cccnc2)nc2[nH]ccc12 +C=CCOC1=CCCN(C(=O)OCc2ccccc2)C1 +CCc1onc(C)c1NC(=O)N1CCN(S(=O)(=O)CC)CC1 +O=C(Nc1ccccc1)NC1CCc2cc(F)ccc21 +Cc1ccc(C(=O)Nc2cc(Cl)cc(C)c2O)c(=O)[nH]1 +CCOC(=O)CN(C(C)C)S(=O)(=O)c1ccccc1F +Cc1csc(=O)n1CCC(=O)N1CC=C(c2ccccc2)CC1 +O=C(c1ccc(N2CCOCC2)nc1)N1CCCC1C1CCCC1 +CC1Cc2cc(S(=O)(=O)NCCc3ccccc3)ccc2N1 +Cc1cc(C(=O)NC(c2ncnn2C)C2CC2)c2ccc(C)c(C)c2n1 +CC1(C(=O)NCc2ccccn2)Oc2ccc(Cl)cc2NC1=O +N#Cc1ccc(NC(=O)c2cc(Br)ccc2F)cc1 +COc1ccc(C(=O)Cc2ncc[nH]2)cc1Br +CCc1nc2n(n1)CCCC2NC(=O)Nc1cc(C(C)C)on1 +COCCOc1cccc(C(=O)Nc2nc(C)cs2)c1 +CCCCc1nc(Cn2cnc(C3CCC3)cc2=O)no1 +COc1ccc2c(c1)C(C)N1C(=O)c3ccccc3C1O2 +Cn1ccc(N)c1Cc1ccc(Br)cc1 +Cc1cc(C(=O)N2CCCCC2c2cccc(C)c2C)ncn1 +Cc1nc(-c2cccc(CNC(=O)c3c(C)[nH]c4ccccc34)c2)n[nH]1 +CCCCn1nnc(CO)c1-c1ccccc1Cl +Cc1noc(NC(=O)CCc2nc(-c3ccncc3)no2)n1 +Cc1ccc(S(=O)(=O)Nc2ccc(CC(=O)N(C)C)cc2)cc1C +NC(=O)CN(Cc1ccccc1)c1cccc(NC(=O)c2ccoc2)c1 +Cc1oc2ncn(CCC(=O)NCCN3CCOCC3)c(=O)c2c1C +NC(c1ccc(F)cc1)c1nc(-c2ccc(O)cc2)n[nH]1 +O=C(NCCCN1CCCC1=O)c1cncc2cnccc12 +Cc1cccc(NC(=O)COc2ccc(C#N)cc2)n1 +COC(CNC(=O)c1cn(CC(=O)N(C)C)nn1)c1ccccc1 +CC(=O)c1ccc(OC(C)C(=O)Nc2ccc(CC#N)cc2)cc1 +COc1cc(C)c(C)cc1CC(=O)NCCCO +Cc1noc(C)c1CCCNC(=O)C1CC(=O)N(C(C)C)C1 +CCOc1ccc(Cc2ncc(N)cn2)cc1Cl +CC1CN(C(=O)Cc2ccc(-n3cccn3)cc2)c2ccccc21 +COc1cccc(CNC(=O)CCn2cc(C)cn2)c1OC +CCN1CCN(C(=O)C(C)Oc2ccc(C#N)cc2)CC1 +CCc1nn(CC(=O)N2CCOCC2)c(=O)c2cc3sccc3n12 +CCCCN(C)C(=O)CSc1nnc(C)n1N +CC(C)c1cc(C(=O)OCCNc2cccnn2)n(C)n1 +Cc1ccc(C(=O)OCC(=O)Nc2cc(C)n[nH]2)c(C)c1 +FC(F)(F)OCCn1cc(Br)cn1 +Cc1cccc2nc(C(=O)Nc3nccs3)cn12 +COc1ccc(CN2C(=O)c3ccccc3S2(=O)=O)cn1 +CC(Oc1ccc(F)c(F)c1)C(=O)N1CCCC1c1ccc[nH]1 +O=C(CC1(O)CCCCC1)NCCCn1nc2n(c1=O)CCCC2 +Fc1cccc(Cl)c1CN1CCC2(CC1)OCCO2 +O=C(NCc1ccccc1OC1CCC1)c1cccc(-n2cccn2)n1 +CCc1cccc(OC2CN(C(=O)C(CC)N3CCOCC3)C2)c1 +O=C(NCCc1ccc(F)c(Br)c1)c1ccoc1 +COc1cc(NC(=O)CCc2cc(C(C)=O)c(C)o2)cc(OC)c1 +Cc1noc(NC(=O)c2cccc(Cl)c2Cl)c1C#N +CCCOCCOC(=O)c1ccc(N)cc1Cl +COCC(O)c1cc(C)c2c(c1)C(NC(=O)C(C)C)CCO2 +Cc1cccc(OCCNC(=O)Cn2c(C)c(C)sc2=O)c1 +CC1(C)CN(C(=O)Nc2cccc(OC(F)F)c2)CCO1 +CN1CCN(C(=O)COC(=O)c2ccc(F)cc2)CC1 +CCOC(=O)COc1cccc2c(C)cc(=O)oc12 +CCN1CC(c2nc3ccccc3n2Cc2ccccc2C)CC1=O +Cc1c(C(=O)N(CC(N)=O)C(C)C)cnn1-c1cccc(Cl)c1 +COC(CNC(=O)CCc1cccnc1)c1cccc(Cl)c1 +CCCC(=O)Nc1cc(C(=O)OC)ccc1Cl +O=C(Cc1ccccc1Cl)Nc1ccc2c(c1)OCO2 +CNC(=O)c1cc(C)ccc1NC(=O)c1ccc(F)cc1 +COC(=O)CN1CCc2nc(NC(=O)c3cnccn3)sc2C1 +CC(C)CC(C(=O)Nc1nc(C(C)C)cs1)N1CCCCC1=O +COc1cc(Cl)c(C)cc1NC(=O)c1ccncc1 +O=c1c2cccnc2ncn1Cc1cc(-c2ccccc2)on1 +COC(=O)NCCC(=O)N1CCOc2ccc(F)cc21 +CC(Sc1ccc(C(F)(F)F)cn1)C(=O)N(C)C +Cn1cc(NC(=O)c2ccc(CSc3ccccc3)cc2)cn1 +COc1ccc(-c2cc(-n3cccn3)ncn2)c2cccnc12 +COc1ccccc1CC(C)N(C)Cc1nc2ccccc2c(=O)[nH]1 +CCOC(=O)c1sc(C(C)NC(=O)C#Cc2ccccc2)nc1C +Cc1cc(CN(C)C(=O)Cc2cccs2)no1 +CN(C)C(=O)COc1cccc(NC(=O)c2cccs2)c1 +O=C(Nc1ccc2c(c1)OCCCO2)c1n[nH]c2c1CCCCC2 +Cc1cccc(C(=O)Nc2noc3nc(C)ccc23)c1 +CCCCNC(=O)C1CCCN(C(=O)CCC(C)C)C1 +Cc1c(C2CCCN(C(=O)c3ccn(C)n3)C2)n2c(nc1=O)CCC2 +Cc1ccc(C(=O)Nc2nnc(C(F)(F)F)s2)o1 +CCn1cc(C(=O)N2CCCC(c3ccnc4ncnn34)C2)cn1 +COc1ccccc1-n1ccnc(NC(=O)c2ccco2)c1=O +CCC(C)NC(=O)Nc1ccc(OCC(F)(F)F)nc1 +Cc1ccc(C(NC(=O)Nc2nnc(C3CC3)s2)C(C)(C)C)o1 +COc1ccc2[nH]c(-c3cccs3)cc(=O)c2c1 +COCc1cccc(C(=O)NC(C(=O)OC)C(C)C)c1 +Cc1cc2ccccc2n1CCCNC(=O)c1ccco1 +CCn1nnc2c(Nc3cc(C)ccc3C)ncnc21 +COc1ccc(NC(=O)CSc2c(C)n[nH]c2C)cc1 +Cc1csc(C(C#N)C(=O)c2cn(C)nc2C(C)(C)C)n1 +O=C(CNC(=O)NC1CCC(O)CC1)Nc1cccc2ncccc12 +C=CCNC(=O)c1ccc(-c2ccccn2)nc1N +Cc1ocnc1C(=O)N(Cc1ccccc1)C(C)(C)C +CCc1c(C)nc(N2CCN(c3ncccn3)CC2)[nH]c1=O +CN(C)c1ccc(NC(=O)C2CCCN2C(=O)c2cccs2)cn1 +O=C(c1cccc(F)c1)N1CC(c2nc(-c3ccccc3)no2)C1 +COc1ccc(CC(=O)N2CCCCC2Cn2cccn2)cc1 +Cc1ccc(-c2nnc(SCC(N)=O)n2-c2ccc(C)cc2)cc1 +CC(=O)N1CCC(C(=O)Nc2nnc(CC(C)C)s2)CC1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1c(C)cccc1C +CC(C)CC1NC(=O)C(Cc2c[nH]c3ccccc23)NC1=O +CCCCN(CC(N)=O)C(=O)Cn1nc2ccccn2c1=O +Nc1ccc(NC(=O)COc2ccccc2)cc1F +COc1ccccc1OCCN(C)C(=O)c1cccc(OC)c1F +CC(Nc1ccc2oc(=O)[nH]c2c1)C(=O)NC1(C#N)CCCCC1 +CCOC(=O)CNC(=O)n1nc(C)c2ccccc21 +CC(C)(C)C(C#N)NC(=O)C1CCN(C(=O)c2ccccn2)CC1 +Nc1nc(COC(=O)c2ccccc2F)nc(Nc2ccccc2)n1 +Cc1cc(CN2CCN(C(=O)COc3ccccc3Cl)CC2)on1 +COCCN1CCN(Cc2nnc(C(C)(C)C)o2)CC1=O +CCOC(=O)c1ccc(CNC(=O)c2cccc(OC)c2F)o1 +Cc1ccc(C(=O)Nc2ccc(C(=O)N3CCCC3)cc2)cc1 +COCCC(=O)Nc1c(N)n(CC(C)C)c(=O)n(C)c1=O +COC(=O)c1c(C)[nH]c(C(=O)NC(C)CCc2ccccc2)c1C +COc1ncccc1C(=O)NC1CCCOc2ccc(F)cc21 +CC(C)(C)c1csc(CNC(=O)C2CCCC2)n1 +Cc1ccc(Cl)cc1N1CCN(C(=O)NCc2ncn(C)n2)CC1 +Cc1nc(CNC(=O)Nc2c(C)ccn(C)c2=O)c(C)s1 +CC1Cc2ccccc2N1C(=O)CNc1ccccc1N1CCCC1=O +O=c1cc(C2CCC2)ncn1Cc1cccc(C(F)(F)F)c1 +CCCCNC(=O)C1CCN(C(=O)c2cc(C)no2)CC1 +CN(CC(=O)NCCN1CCc2ccccc21)Cc1ccc(C#N)cc1 +CC(C)OCCCn1c(SCC#N)nc2ccccc2c1=O +COc1ccc(NC(=O)Cn2ccc3ccc(F)cc32)cn1 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1ccc(F)cc1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)C(=O)C1(O)CCCC1 +CCS(=O)(=O)NC1CCOc2ccc(C(C)O)cc21 +COc1cc(NC(=O)c2cc(C(N)=O)cs2)cc(OC)c1 +COc1cccc(C(=O)N(C)C(C)c2ccco2)c1OC +COC(=O)c1ccc(N2CCC3(CCCCC3)C2)nn1 +c1cc(-c2ccc3[nH]c(-c4ccncc4)nc3c2)ccn1 +O=C(NCCCOCC1CCCO1)c1cc2c(s1)CCCC2 +Cc1csc(CN2CCNC(=O)C2C(C)C)n1 +O=C(c1cccnc1)N1CC=C(c2ccccc2)CC1 +COc1c(NC(=O)Cc2csc(-c3ccoc3)n2)c(C)nn1C +CC(=O)Nc1ccc2[nH]c(-c3cccn3C)nc2c1 +CCc1cccc(C)c1NC(=O)c1cc(Cl)ccc1N +CCc1nc(C2CCCN2C(=O)c2ccnc(C3CC3)n2)no1 +Cc1ccc2cccc(C(=O)Nc3ccc4c(c3)OCO4)c2n1 +O=c1cc[nH]cc1NCc1ccc(Cl)cc1F +Cc1cccc(CCC(=O)N2CCCc3cccc(N)c32)c1 +N#Cc1ccc(N2CC3(CCN(C(=O)c4c[nH]cn4)C3)CC2=O)cc1 +CC1CCCC(CNC(=O)c2ccc(=O)n(-c3ccc(F)cc3)n2)C1 +C#CCOc1ccccc1C1CC(=O)Nc2c1cnn2-c1ccccc1 +COC(=O)Cn1ncc(N2CCCCCC2)c(Cl)c1=O +CSc1cc(C(=O)N2CC(C)Sc3ccccc32)ccn1 +COC(=O)c1ccc(N)c(Oc2cccc(F)c2)c1 +CCOc1ncccc1NC(=O)NCC(=O)Nc1ccc(O)cc1 +Cc1ccoc1CN1CCN(C(=O)c2ccc(F)cc2Cl)CC1 +NC(=O)C1CCN(C(=O)c2cc3ccccc3s2)CC1 +CC(C)c1cc(Br)ccc1NC(=O)c1ccncc1 +CCCn1nccc1C(=O)NC(C)c1ccc(OC)cc1 +CCN(CC)C(=O)Cn1nnc(-c2cccc(C(F)(F)F)c2)n1 +Cc1ccc2ncc(C(=O)NCCCCn3ccccc3=O)n2c1 +O=C(Nc1ccc(-n2ccnn2)cc1)c1cccnc1OCC(F)F +Cc1ccc(-c2cnc3ccccc3n2)cc1NC(=O)c1ccncc1 +Cc1cc(C(N)=O)c(NC(=O)c2cccc(-n3cccn3)n2)s1 +CCCOc1ccc(Cl)cc1NC(=O)Cn1cnnn1 +Cc1noc2ncnc(N3CCCC(C(=O)NC4CCCC4)C3)c12 +CCNc1ccc(C(=O)Nc2cccc(C)n2)cc1 +Cc1csc(C(C#N)C(=O)c2cnn(CC(C)C)c2C2CC2)n1 +COC(=O)c1ccoc1COC(=O)c1ccc2c(c1)OCC(=O)N2 +Cc1cc(C)n(-c2ccc(C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)cn2)n1 +Cc1ccc(C=Cc2ccn(CCCC#N)c(=O)c2)cc1 +NC(=O)CCN(C(=O)CCc1ccccc1)c1ccccc1 +CC(=O)N(c1ccccc1)S(=O)(=O)c1ccc(C)cc1 +Cc1ccc(C(=O)Cn2ncc(Cl)c(Cl)c2=O)cc1 +COc1ccc(CNC(=O)c2cnn3ccc(C)cc23)cc1 +COc1cc(NC(=O)CCC(=O)c2ccc(C)s2)cc(OC)c1 +CCc1cc(C#N)c(NC(=O)c2cc(F)ccc2F)s1 +CC(OC1CCN(C(=O)OC(C)(C)C)CC1)c1ccc[nH]1 +COCCNC(=O)Cn1nnn(-c2cccs2)c1=O +Cc1cc(C(=O)NCC(N)=O)c(C)n1Cc1cccs1 +CCC(C)NC(=O)C(C)NC(=O)NCC(=O)NC(C)C +CCCC1CN(C(=O)Cc2ccc3c(c2)OCO3)CCO1 +O=C(NCc1cccc(Cn2ccnc2)c1)Nc1cnc(C2CC2)nc1 +CC(C)n1cnnc1SCC(=O)Nc1cccc2cccnc12 +COc1ccc(CC(=O)Nc2cccc3cccnc23)cc1OC +N#Cc1c(N)[nH]c(=O)c(C#N)c1-c1cccc(O)c1 +CC(=O)Nc1nc2cc(NC(=O)NCC(C)C)ccc2s1 +Cc1cc(C(C)NC(=O)Nc2cn[nH]c2)c(C)s1 +Cc1ccccc1-c1noc(-c2cc3c(CO)cnc(C)c3oc2=O)n1 +CCOCC(=O)N1CCCCC1CCc1cccc(O)c1 +Cc1ccc(-c2ccsc2C(=O)N2CCc3[nH]ncc3C2)cc1 +CCCCCCn1c(C)cc(=O)c(O)c1CN1CCOCC1 +CCNC(=O)C(C)NCc1cc(OC)ccc1OC +Cc1nc(C(C)C)c(C(=O)NCCc2c[nH]c3ccccc23)s1 +COc1cc(OC)cc(OC(C)C(=O)Nc2ccc(F)cc2)c1 +CC(=O)Nc1cc(NC(=O)NCCO)ccc1C +CN(CC(=O)NC1CCCCC1)S(=O)(=O)c1ccc(F)cc1 +CCCC(C)C(=O)NCCNC(=O)c1ccc(Br)cc1 +C=CCOc1ccc(C(=O)Nc2cccc(NC(C)=O)c2)cc1 +CCOc1ccccc1C1CC(=O)Nc2c1cnn2C1CCCC1 +CC(C)C(=O)NCCNC(=O)c1cc(Cl)ccc1F +CC(NC(=O)Nc1ccc(F)c(C(F)(F)F)c1)c1nncn1C +Cc1cc(C)nc(NCCNC(=O)OC(C)(C)C)n1 +CN1CCC(NC(=O)NC(Cc2ccccc2)C(F)(F)F)C1=O +COc1ncccc1NC(=O)NCCC(=O)N1CCCC1 +COC(=O)C1=C(C(=O)OC)c2cccc3cccc1c23 +Cc1ccsc1CC1(c2ccco2)NC(N)=NC1=O +CCC(=O)CCc1cc(OC)c(OC)c(OC)c1 +CCNC(=O)N(C)Cc1nc(-c2ccc(OC)c(OC)c2)no1 +CC(c1nnc(-c2cccs2)o1)N1CCN(c2ccccc2)CC1 +CC(Cn1ccnc1)NC(=O)c1cccc(C(F)(F)F)c1 +O=C(Nc1nccs1)c1cccc(N2C(=O)CCS2(=O)=O)c1 +COCCC(=O)N1CCCN(Cc2ccccc2)c2ccccc21 +CCCCC(=O)Nc1ccc(C(=O)NC2(CO)CCCC2)cc1 +O=S(=O)(NCCc1ccccc1F)N1CCCCCC1 +Cc1ccccc1NC(=O)Cn1cnc(-c2ccccc2)cc1=O +CC(O)(CNC(=O)c1cnn(C(C)(C)C)c1)c1ccc(F)cc1F +CC(C)(C)OC(=O)N1CCC(OC(=O)c2scnc2C2CC2)C1 +CCCn1nc(-c2ccc(OCC)cc2)cc(CO)c1=O +O=C(OCC1CCCO1)C1CCCN1C(=O)c1ccco1 +CN(Cc1ccccc1)c1ccc2ccc(C(=O)NC3CC3)cn12 +COc1ccc(C(=O)N(C)C)cc1NCC#Cc1ccc(Cl)cc1 +Cc1ccc(C)c(S(=O)(=O)Nc2ccc3c(c2)NC(=O)CO3)c1 +COc1ccc(Cc2nc3cccc(C)n3c2CO)cc1 +COc1ccc2c(c1)CCCN2C(=O)c1cnc2n(c1=O)CCS2 +CC(C)NC(=O)c1cccc(CNC(=O)N2CCCC(CO)C2)c1 +N#CC1(Nc2cccc(Br)c2)C(=O)Nc2ccccc21 +Cc1cccc(CNS(=O)(=O)c2ccccc2C(F)(F)F)n1 +CC(C)c1nnc(SCC(=O)Nc2ccc(Cl)cc2Cl)o1 +CC(C)N(C)S(=O)(=O)c1ccc(NCc2ccc(CO)cc2)cc1 +Cc1ccc(-c2nnc(COc3cccc4cccnc34)o2)cc1 +Cc1c(C(=O)Nc2ccc(F)cc2F)cnn1C +Cc1ccc(NC(=O)C2(O)CCCC2)cc1S(=O)(=O)NC1CC1 +CN(CCc1ccccc1)S(=O)(=O)c1ccc(F)c(F)c1 +Cc1ccc(OCC(=O)Nc2ccnn2Cc2cccs2)cc1 +O=C1CCCc2[nH]c(=O)c(C(=O)Nc3ccc(Cl)cc3)cc21 +CN(C)C(=O)CNC(=O)c1sc2ccccc2c1Cl +COc1ccccc1NC(=O)Nc1cn(C)c2ccccc12 +COc1ccccc1CC(=O)Nc1cnc2c(c1)c(C)nn2C +CCC(=O)c1ccc2c(c1)N(CCN1CCOCC1)C(=O)CO2 +CCn1nc(C(=O)Nc2cccnc2)c(=O)c2cc(F)ccc21 +Cc1nc2ccc(NC(=O)c3cccc(S(C)(=O)=O)c3)cc2o1 +CCc1ccc(NC(=O)CCSc2cc(C)ncn2)cc1 +COC(=O)CC1CCCCN1C(=O)c1cn[nH]c1 +CCC(C)NC(=O)CCc1c(C)nc2c(c(C)nn2C)c1C +Cc1ccc(CC(C)NS(=O)(=O)Cc2cccc(C#N)c2)s1 +Cc1ncsc1CCOC(=O)c1ccc(C(N)=O)cc1 +O=C(Nc1ccccc1)Nc1ccc(C(=O)N2CCCCC2)cc1 +COc1cc(C)c(C)cc1-c1cn2cc(N)cc(OC)c2n1 +COc1ccc(NC(=O)CC2C=CCC2)cc1Cl +CCCS(=O)(=O)Nc1cccc(N2CCCS2(=O)=O)c1 +COc1cc(C#N)ccc1OCC(=O)Nc1cccc(C)c1C +CC(C)(C)OC(=O)NCCNC(=O)c1cccs1 +CCNC(=O)NC(C)c1ccc(OCC)c(OC)c1 +O=C(COc1ccc(F)cc1)Nc1nnc(-c2ccc(F)cc2F)o1 +COc1cc(C)c(-c2cc(C#N)nn2CCCO)c(C)c1 +CCn1ncc(NC(=O)c2cc(C)c(C)s2)c1C(=O)N(C)C +CCN(CC(C)C#N)C(=O)CNc1ccc(F)cc1Cl +Cc1cnn(C2CCCN(C(=O)C3CC=CCC3)C2)c1 +O=C(CN1CCN(c2ccc(F)c(F)c2)C1=O)Nc1ccccc1F +CN(c1ccc(OCc2cccc3cccnc23)cc1)S(C)(=O)=O +O=C(CNC(=O)C1CCCCC1)OCC(=O)c1ccc(F)cc1 +Cc1cc(C)n(CCCNC(=O)c2c(C)oc3ncn(C)c(=O)c23)n1 +CCC(NC(=O)c1ccc(S(N)(=O)=O)o1)c1ccc(OC)cc1 +CC12CCC(C(=O)N(c3ccccc3)c3ccccc3)(OC1=O)C2(C)C +O=S(=O)(Cc1ccc(Cl)cc1)N1CCCCCC1 +CCN(C)S(=O)(=O)N(CC)Cc1ccc2c(c1)OCO2 +COCCn1c(-c2cn(C)nc2C(C)C)nc2ccccc21 +Cc1nc(CC2NC(=O)c3ccccc32)n(-c2ccc3c(c2)OCO3)n1 +O=C1C(NC(CO)c2ccccc2)CCN1c1c(F)cccc1F +CCCn1nc(CO)cc1-c1ccccc1OCC +Cc1ccc(OCC(=O)Nc2nc(C)c(C)s2)c(C)c1 +CCOc1nccnc1NC1CCN(C(=O)c2cccnc2)CC1 +CCCn1c(C)cc(C(=O)CSc2nnc(C(C)C)[nH]2)c1C +CNc1c(F)cc(C(=O)N(CCO)CCO)cc1F +CCC(Cn1ncc2ccccc2c1=O)NC(=O)CC1CCCC1 +Cc1cc(C)n(CC(C)CNC(=O)c2cc(C3CC3)[nH]n2)n1 +CC(C)N(CC(N)=O)C(=O)CCc1cccc(Cl)c1 +CCOc1cc(C2OCCCO2)cc(N)c1OCC#N +CCN(CC1COc2ccccc2O1)C(=O)CC(C)(C)C +CCOCc1ccc(CNC(=O)c2cccc3ccc(C)nc23)cc1 +CNC(=O)C1CN(C(=O)Cc2ccc(C)cc2)CC12CCCC2 +COc1cccc(C(=O)N(C)c2ccc(Cl)cn2)c1OC +CC(C)c1noc(CCNC(=O)C2CC3C=CC2C3)n1 +Fc1ccc(CCNc2ncnc3ncccc23)cc1 +Cc1nnsc1Cn1cnc2sc3c(c2c1=O)CCNC3 +O=C(CCC(=O)c1cccs1)NCC1Cc2ccccc2O1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCc1ccco1)O2 +N#Cc1ccc(NC(=O)NCc2cn3ccccc3n2)cc1 +CC(C)NC(=O)C(C)Oc1cc(Cl)ccc1N +COc1cccc2cc(CNC(=O)N3CCC(C(N)=O)CC3)oc12 +COC(=O)C1CCCCN1S(=O)(=O)c1ccc(C(C)=O)cc1 +O=S(=O)(NC1CCC(O)CC1)C1=Cc2ccccc2CC1 +CC(c1ccccc1F)N1CCOC(C(N)=O)C1 +CNC(=O)CC(c1ccc(OC)c(OC)c1)C(C)C +CNS(=O)(=O)c1cc(N)c2c(c1)CCN2C(C)=O +O=C(OCc1nccs1)c1ccc(N2CCCS2(=O)=O)cc1 +Cn1nc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)ccc1=O +COCCS(=O)(=O)N(Cc1ccccc1N)C1CC1 +CCN(CCc1ccccc1)C(=O)c1csc(-c2ncccn2)n1 +Cc1cc(C(=O)Nc2nc3ccccc3s2)n(C)n1 +CNC(=O)c1ccc(CSc2nncn2-c2ccccc2)cc1 +Cc1cccc(Nc2nccc(-c3cn(C)nc3C)n2)c1 +CCc1ccc(C(NS(=O)(=O)CC)C(C)(C)C)o1 +NC(=O)C(NC(=O)c1ccon1)c1ccc(F)cc1 +C#Cc1cccc(NC(=O)N2CCC(C(=O)NCCCOC)CC2)c1 +COCCN(CC(C)C)C(=O)c1cc(C)c(C)s1 +O=C(Nc1ccc(OC(F)F)cc1)c1cc(C2CC2)on1 +CCCc1nc(CN2CCCN(CC(F)(F)F)CC2)no1 +COc1ccc(NC(=O)CS(=O)(=O)c2ccc(OC)cc2)cc1 +CN1C(=O)CCc2cc(C(=O)N(C)c3cccc4ncccc34)ccc21 +CCn1nc(-c2ccc(OC(C)C)cc2)cc(C#N)c1=O +O=C(C1CC1)N1CCOC(c2ccccc2C(F)(F)F)C1 +O=C(Cc1nnc(-c2ccccn2)o1)NCc1ccc(Cl)cc1 +CSc1ccc(NC(=O)NCC(O)C2CC2)cc1F +CS(=O)(=O)N1CCN(c2nc3c(c(=O)[nH]2)CCCCC3)CC1 +O=C(c1cccs1)N1CCC2COC(CNc3ncccn3)C2C1 +O=S1(=O)c2ccccc2N=CN1Cc1cc(F)cc2cccnc12 +C=CCSc1nnnn1-c1ccccc1OCC +CC(=O)C1(c2ccccc2)CCN(Cc2nnc(C)s2)CC1 +CC(N(C)C(=O)c1cn(C)nc1-c1cccs1)C1(C)CC1 +CCc1ccc(Cc2nnc(NC(=O)c3ccc(C#N)cc3)o2)cc1 +CCCOc1ccc(NC(=O)C(C)OC)cc1Cl +O=S(=O)(Cc1ccon1)c1ccc(C(F)(F)F)cn1 +CCOCCC(=O)NCC1COc2ccccc2O1 +COc1ccccc1NS(=O)(=O)c1cc(C(=O)N(C)C)ccc1C +O=C(NCc1ccccc1-n1cccn1)C1COc2ccccc2O1 +COC1CN(Cc2ccc(F)cc2)C2CCCOC12 +COc1cccc(CN(C)C(=O)c2ccc(C)[nH]c2=O)c1OC +Cc1noc(C2CCN(C(=O)C3CC(=O)Nc4ccccc43)CC2)n1 +Cc1ccc(C)c(NCC(=O)Nc2ccccc2C#N)c1 +CC(NS(C)(=O)=O)C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cc1nn(-c2ccccc2)c(CSc2ncccn2)c1C#N +COc1cc(-c2noc(CCc3cccc(F)c3F)n2)ccn1 +CCCCC(=O)N1CCN(c2nc3cccnc3n(CC)c2=O)CC1 +COC(C(=O)N1CCC(n2cncn2)CC1)c1ccccc1 +CC(NCc1cnc(C2CCC2)s1)C(O)c1c(F)cccc1F +O=C(NC1CC1)c1cccc(OS(=O)(=O)c2cccnc2)c1 +CCOC1CCCN(C(=O)c2cc(Br)ccc2Cl)C1 +COC(=O)CCN(C)S(=O)(=O)c1c[nH]nc1N +Cc1cc(N)ccc1S(=O)(=O)N1CCOCC1 +CC1CCCCN1C(=O)CSc1nncn1-c1ccccc1 +COc1ccccc1NC(=O)c1c(C)cccc1N +CC(=O)Nc1cccc(NC(=O)C(C)Nc2ccc(C)c(F)c2)c1 +Cn1ccc2ccn(CC(=O)NCCc3ccc(Cl)cc3)c(=O)c21 +Cn1c(=O)n(Cc2ccncc2)c(=O)c2cnc(-c3cccnc3)nc21 +Cn1cc(C(=O)NC2CCN(C(=O)c3ccccc3Cl)CC2)cn1 +CC1CCCCC1OCC(=O)Nc1cccc(N)c1 +O=C(Cn1cc(NC(=O)NCc2ncc[nH]2)cn1)NC1CCCC1 +COc1cccc(S(=O)(=O)CCCOc2ccc(F)cc2)c1 +CC(C)OCc1cccc(CNC(=O)CC(F)(F)F)c1 +CCc1nnc(NC(=O)CCC(=O)NCC2CCC2)s1 +CC(NC(=O)C1CCCC1)c1ccc(NC(=O)C2CC2)cc1 +COC(=O)C(NC(=O)c1cnn(-c2ccccc2F)c1C)C(C)C +COC(=O)Nc1cc(NC(=O)c2ccc(C)c(C)c2)ccc1F +COc1ccc(CNC(=O)CCCn2c(=O)oc3ccccc32)cn1 +O=C(CCc1ccsc1)OCC1COc2ccccc2O1 +c1csc(CN(Cc2cccc3cccnc23)CC2CCCO2)c1 +O=C(CN1Cc2ccccc2C1=O)Nc1ccc2ccccc2n1 +N#Cc1cccc(Nc2ccc(CN3CCOCC3)cc2)c1 +O=c1[nH]c(=O)c2sc3nc(-c4ccccc4)ccc3c2[nH]1 +NC(=O)c1cc(Cl)ccc1OCC(=O)Nc1cc(F)ccc1F +Nc1ccc(F)c(S(=O)(=O)N2CCCC(CO)C2)c1 +N#CC(C(=O)CCSc1ccccn1)c1ccccn1 +Cc1ccc(CNC(=O)CCn2ncc3cc(Cl)ccc32)o1 +CN(C)C(=O)CNC(=O)c1cc(-c2cccnc2)nc2ccccc12 +Cc1cccc(NCc2ccc(F)c(C#N)c2)c1O +CCN(CC)C(=O)C1CCN(C(=O)Nc2ccc(C(N)=O)cc2)CC1 +Cn1ccc2ccn(Cc3nc(-c4ccncc4)no3)c(=O)c21 +N#CC1(Nc2ccc(S(N)(=O)=O)cc2)CCCC1 +CC(C#N)Cn1c(C2CCC2)nc2cc(F)c(F)cc21 +CCOC(C)C(=O)Nc1cc(Br)c(=O)n(C)c1 +Cc1cc(F)ccc1S(=O)(=O)N(C)C(C#N)c1ccco1 +CC(C(=O)Nc1ccccc1S(C)(=O)=O)c1ccsc1 +CC(=O)N1CCC2(COCc3cnc(NCC4CC4)nc32)C1 +COc1ccc(C(=O)N2Cc3ccccc3CC2C(N)=O)c(OC)c1 +COc1cc(-c2cn3cc(N)ccc3n2)c(OC)cc1C +COc1ccc(C(=O)N(C)C2CCC(C)CC2)c(OC)c1OC +CCCc1nnc(SCC(=O)c2ccccc2)o1 +Nc1ccc(NCCN2CCOCC2)c(Cl)c1 +CCN(Cc1nc(-c2ccc(C)cc2)no1)C(=O)c1ccco1 +COC(C)C(=O)N1CCN(c2ncnc3sccc23)CC1 +CCn1cc(S(=O)(=O)N(C)Cc2c(Cl)cnn2C)cn1 +Cc1cc(NC(=O)N2CCC(NC(=O)c3cccnc3)CC2)no1 +O=C(Nc1cnccc1SCCCO)c1cc2occc2[nH]1 +COc1ccc(C=C(NCc2ccccc2)NC(C)=O)cc1OC +O=C(Nc1cccc(F)c1)c1cc2scnc2[nH]1 +COc1cc(N2CCOC(C)(C)C2)ccc1NC(C)c1cnn(C)c1 +CC(=O)Nc1cc(C(=O)N(CC2CCCCC2)C2CC2)ccc1C +COc1ccccc1NC(=O)N1CCN(Cc2cccc(O)c2)CC1 +CCc1nc(NCCO)c2cc(CC)sc2n1 +C=CCN(CC=C)C(=O)Cc1noc2c(N)cc(F)cc12 +O=C(NCc1cccs1)C1CCCN(c2nnc3ccccn23)C1 +CCCCCC(C)NC(=O)c1cn(-c2ccc3c(c2)OCCO3)nn1 +O=C(Nc1ccccc1C(=O)NC1CC1)c1cc2ccccc2o1 +CC(Cc1ccccc1C(F)(F)F)NC(=O)c1ccnn1C +CC(C)N1CCN(C(=O)CC2Sc3ccccc3NC2=O)CC1 +Cc1ccc(-c2snnc2C(=O)Nc2c(C)nn(C)c2C)cc1 +CC(=O)N1CCc2nc(C)nc(N3CCCCC3)c2C1 +CCN1CCC2(CCN(C(=O)c3ccsc3)CC2)C1=O +COCc1nc2ccc(Cl)cc2n1CC(C)C +Cc1cccnc1NC(=O)Cc1cc(-c2ccc3c(c2)OCO3)on1 +O=C(Nc1ccccc1Cl)c1nc(-c2cnccn2)no1 +C#Cc1cccc(N(C(=O)Cc2cc(C(C)=O)ccc2OC)C(C)C)c1 +CCC(C)(C)C(=O)Nc1cnn(-c2ccccc2)c1 +CC1CN(C(C)CNC(=O)NC(C)c2nncn2C)CC(C)O1 +C=CCc1cc(CNc2cnn(-c3ccccc3)c2)cc(OC)c1O +CC(Oc1ccccc1)C(=O)NCc1ccnc(OC2CCC2)c1 +FC(F)(F)c1cccc2c1CCNC2c1cc[nH]n1 +CC(=O)Nc1ccc(S(=O)(=O)CC(=O)N2CCCCC2C)cc1 +Cc1nc2c(c(C)c1CC(=O)NCC1CCCC1)c(=O)[nH]n2C +N#CCc1c(-c2cccnc2)nc2c(F)cccn12 +Cc1ccccc1C(C)NC(=O)c1cccnc1N1CCOCC1 +COc1ccc2ncnc(Nc3cccc(O)c3)c2c1 +CC(=O)N1CCC(NC(=O)N(C)Cc2c(C)noc2C)CC1 +O=C(NC(c1ccccc1)C1CC1)c1cn2cccnc2n1 +COc1ccc(C(=O)Nc2cc3c(cc2Cl)NC(=O)CO3)cc1 +CN(CC1CCOC1)C(=O)c1cccnc1OCC(F)F +COc1ccc(C(C)NC(=O)COC(=O)c2ccc(F)cc2)cc1 +CCC(=O)N1CCC(C(=O)c2cc(C)c(OC)cc2C)CC1 +Cc1nnc(COc2ccc3ccncc3c2Br)o1 +Cc1cccc(NC(=O)C2(c3ccc(Cl)cc3)CCOCC2)n1 +Cc1csc(NC(=O)Cc2cc(-c3cc4ccccc4o3)on2)n1 +CNC(=O)c1ccc(CNCC(c2ccco2)N(C)C)cc1 +Cc1sc2ncnc(SCCC(=O)NCC(N)=O)c2c1C +Cn1nc(C(=O)Nc2ccc(C#N)cc2)c(=O)c2cc(F)ccc21 +CC(=O)Nc1ccc(OCc2cc(-c3ccccc3)on2)cc1 +O=C(CC1CCN(C(=O)c2ccccc2)CC1)NC1CC1 +CCOc1ccccc1NC(=O)c1cccc(CN2CCCC2=O)c1 +CC(C)C(O)c1cc(Br)cc2c1NC(=O)CC2 +COC(=O)c1ccc2c(c1)nc(C(C)(C)C)n2CC#N +CC(C)(C)n1ncn(CC(=O)NCc2ccccc2)c1=O +CCCCS(=O)(=O)NCc1ccc(Br)cc1 +Cc1cc(=O)[nH]c(SCc2ccccc2C#N)n1 +Cc1cccc(OCC(=O)N(C)Cc2cc(-c3ccncc3)no2)c1 +CC(C)c1cc(C(=O)NCCCOc2cccnc2)n(C)n1 +CC(=O)Nc1ccc(NC(=O)C(NC(C)=O)C(C)C)cc1Cl +COC(=O)CSc1nnc(-c2ccc(S(C)(=O)=O)cc2)o1 +CN1CCOC(C(=O)Nc2c(O)c(Cl)cc(Cl)c2Cl)C1 +Cc1nn(C)c2ncc(NC(=O)N(C)C(C)CC#N)cc12 +Cc1cccc(C(=O)NCCc2nc3cccnc3n2C(C)C)c1 +COc1ccc(OCCOCC(F)(F)F)c(N)c1 +Cc1[nH]c2ccccc2c1-c1cnc2sccn12 +O=C(CCc1c[nH]c2ccccc12)Nc1ccc2c(c1)OCC(=O)N2 +CN(C(=O)c1ccc(Cl)c(Cl)c1)C1(C#N)CCCC1 +Cc1cc(NC(=O)NC(Cc2ccccc2)C2CC2)n(C)n1 +COc1cccc(C(=O)Nc2cnn(CC(=O)NC3CCCC3)c2)c1 +Cc1cnc(C(=O)N2CCCC2C(=O)Nc2ccccc2)cn1 +COc1ccc(Cc2nnc3sc(Cn4ccnc4)nn23)cc1 +CS(=O)(=O)N1CCN(C(=O)CCC(=O)c2ccccc2)CC1 +Cc1cc(C(=O)Nc2ccccc2C(=O)NCc2ccccn2)[nH]n1 +CCOC(=O)CCC(C)NC(=O)C12CC3CC(CC(C3)C1)C2 +CCc1nc2n(n1)CCCC2NC(=O)N(CC)Cc1cccs1 +COc1cccc(CCC(=O)C(C#N)c2nc3ccccc3[nH]2)c1 +CN(CC(=O)N1CCSc2ccc(Cl)cc21)S(C)(=O)=O +CN(C)c1ccc(NC(=O)Cn2c(=O)cnc3ccccc32)cn1 +COC(=O)Nc1cccc(NC(=O)c2cc(F)ccc2C)c1 +O=C1C(n2nnc(-c3ccsc3)n2)CCN1CC(F)(F)F +COCC1c2c(cnn2C)CCN1C(=O)c1c(C)noc1C +CCOC(=O)CN(C(=O)c1c(C)noc1C)C(C)C +C#CCOCC1CCN(C(=O)CCCc2ccccc2)CC1 +CC(NC(=O)Nc1cccn(C)c1=O)C1COc2ccccc21 +Cc1ccc(NC(=O)CC2NC(=O)c3ccccc3NC2=O)cc1C +CCOC1CCCN(C(=O)Nc2cccc(COC)c2)C1 +Cc1nc(NC(=O)N2CCNC(=O)CC2c2ccccc2)oc1C +CC(C)CC(NC(N)=O)C(=O)N1CCN(c2ncccc2C#N)CC1 +COc1ccc(C2CCCN2C(=O)CCOC(C)C)cc1OC +CC(C)CN(C(=O)CC1OC(=O)c2ccccc21)C1CC1 +O=C(NCCc1ccccn1)NCC(=O)N1CCc2ccccc2C1 +COc1ccc(N2CC(C(=O)N3CCCCC3)CC2=O)c(OC)c1 +CC(C)(C)OC(=O)C1C(=CCO)CN1C(=O)OC(C)(C)C +CCc1ccccc1NC(=O)c1ccc(OC)c(N)c1 +CC(C(=O)N(C)CC(=O)NC(C)(C)C)n1nnc(-c2ccccc2)n1 +CC(OCC1CCCO1)C(=O)N(C)c1nccs1 +Cn1c(-c2ccc(F)cc2N)nc2c(F)cccc21 +C#CCN(CCOC)c1c(N)n(CC(C)C)c(=O)[nH]c1=O +Cc1cc(C(=O)N2CCC(c3nc4ccccc4o3)CC2)c(C)o1 +N#Cc1cnc(NC(=O)c2ccc3ncsc3c2)s1 +CNC(=O)C1CCCN(C(=O)NCC2CC23CCc2ccccc23)C1 +O=C(NCCc1ccc(F)cc1)c1ccc(-n2cccn2)cc1 +O=C(COc1ccc(Cl)c2cccnc12)N1CCCCC1 +COCCN1C(=O)c2ccccc2NC1C=Cc1ccco1 +CCC(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccccc1 +CC(C)(CNC(=O)C1CC(=O)N(CC(F)(F)F)C1)c1cccs1 +CC(C)(C)OC(=O)N1CCNC(c2cc[nH]c2)C1 +O=C(NCc1ccccc1Cn1cncn1)c1cccnc1 +CCn1c(C(N)c2ccccc2)nc2ccccc21 +N#Cc1cnn(C(=O)c2ccc(Cl)c(Cl)c2)c1N +CC(=O)NCC1CCN(C(=O)Nc2nnc(C)s2)CC1 +COc1ccc2[nH]c(=O)c(CN(Cc3cccs3)C(C)=O)cc2c1 +COc1ccc(NC(=O)N2CCCCC2c2nc[nH]n2)cn1 +CCOC(=O)C1(NC(=O)c2ccc(OC)c(F)c2)CCCCC1 +CCCS(=O)(=O)N1CCN(c2ccccc2C)CC1 +O=C(CCc1n[nH]c2c1CCCC2)NCc1cc(-c2ccco2)on1 +CC(=O)Nc1cc(NC(=O)C2(C)CC2(Cl)Cl)ccc1C +Cc1csc(NC(=O)C(C)NC(=O)c2ccccc2Cl)n1 +COc1cccc(NC(=O)CCc2nc3ccccc3[nH]c2=O)c1 +COC(=O)Cn1ncc2c3ccccc3n(Cc3ccccc3)c2c1=O +CNC(=O)c1ccc(Cl)c(NC(=O)NCc2ccccc2C)c1 +Cc1cc(C2CCCN(C(=O)Cn3nnc4ccccc43)C2)n[nH]1 +NC(=O)c1ccccc1OCc1nnc(-c2cccc(Cl)c2)o1 +CN(C)C(=O)c1ccccc1NC(=O)c1ccc(Cl)cc1 +CC(C)CC(Nc1nccc(-c2ccncc2)n1)c1ncnn1C +CCOC(=O)CN(C(=O)C1COCCO1)C1CC1 +COc1ccc(OCC2Cn3c(nc4c3c(=O)[nH]c(=O)n4C)O2)cc1 +CC(C)c1noc(CCCC(=O)N2CCCC2c2ccncc2)n1 +CN(C)c1nc(N)nc(CSc2nc3ccccc3c(=O)n2N)n1 +Cc1ccc2nc(NC(=O)c3snnc3C)sc2c1 +CCOC(=O)c1cnn(-c2ccc(C(=O)NCCO)cc2)c1C +CSc1ncnc(NCCc2ccc(Cl)cc2)c1C#N +O=C(NCc1noc(CCc2ccccc2)n1)c1coc(C2CC2)n1 +Cc1ccc(CC(=O)N2CCNC(=O)C2(C)C)c(C)c1 +Cc1cc(C(=O)N2CCOC(c3ccccc3C(F)(F)F)C2)on1 +COC(=O)CN(C(=O)C(C)Sc1ccccc1)C(C)C +N#Cc1ccc(OCC(O)Cn2nc(-c3ccccc3)ccc2=O)cc1 +Cc1nnc(CC2COC3CN(C(=O)Cc4ccccc4C)CC23)o1 +COc1cccc2cc(C(C)NCCc3c(C)nn(C)c3C)oc12 +COc1ccc(C)cc1S(=O)(=O)N1CC(c2nc(C)no2)C1 +Cc1ccc(Cn2c(C(=O)Nc3ccn(C)n3)cc3occc32)cc1 +Cc1nc2n(c(=O)c1C)CCN2CC(=O)NCc1cccs1 +O=C(NCCC(=O)N1CCNCC1)c1cccs1 +Cc1csc(N(C(=O)c2ccc(=O)n(C)c2)c2ccccc2)n1 +Cc1ccc(CNC(=O)N2CCN(c3nccs3)CC2)c(C)c1 +CC(=O)NC1CCN(S(=O)(=O)c2cc(C)ccc2C)CC1 +COc1ccccc1CCN(C)C(=O)C1(O)Cc2ccccc2C1 +CC(=O)Nc1ccc(NC(=O)c2ccc(-n3nncc3C)cc2)cc1 +CCNC(=O)C(C)NC(=O)c1nn(-c2ccccc2)c2c1CCC2 +COc1ccccc1CNC(=O)Cn1ccc2ccc(Cl)cc21 +CCc1onc(C)c1C1CCCN1C(=O)Nc1ccc(F)cc1F +CC(C)(O)CCc1cccc(C(=O)NCc2cn3cccnc3n2)c1 +CSc1ccc(CN(C)CC(C#N)CCC#N)cc1 +CN1CCN(C(=O)c2cnc(Nc3ccccc3)nc2)CC1CCO +CN(CCN(C)C(=O)OC(C)(C)C)C(=O)Nc1ccsc1 +O=S(=O)(c1ccccc1)N(CCO)Cc1ccccc1 +CN1C(=O)Cc2ccccc2C1C(=O)NCc1ccc(Cl)cc1 +CCOc1ncccc1CNC(=O)c1ccc(F)cc1 +CN(C(=O)CCNC(=O)C1CCCO1)c1ccccc1 +CC(=O)c1ccc(OCC(=O)Nc2ccc(F)cc2C)cc1 +COc1ccc(S(=O)(=O)Nc2ccc3oc(=O)[nH]c3c2)cc1 +Cc1cc2c(cnc3ncnn32)c(=O)n1-c1ccccc1Cl +CC(C)C(O)c1nnc2c(-c3ccco3)ccnn12 +CCOC(=O)c1cc(-c2c(O)cc(O)cc2O)n[nH]1 +CC(=O)N(CCc1ccccc1)CC(=O)N(C)c1ccc(Cl)cn1 +O=C(Nc1ccccc1OC(F)F)c1cn2cccnc2n1 +CCN1C(=O)Nc2ccc(C(C)C)cc2S1(=O)=O +COc1ccc(C(=O)N2CCC(O)CC2)cc1NC(C)=O +COc1ccnc(NC(=O)C2(C#N)CCCCC2)c1 +O=C(CSc1n[nH]c(=O)n1CCc1ccccc1)c1ccccc1 +Cc1oc(-c2ccncc2)cc1-c1nnc(NC(C)C)s1 +CN(Cc1ccncc1)C(=O)c1cncc(Br)c1 +COC(=O)C1c2ccsc2CCN1C(=O)CCC1CCCC1 +COC(=O)CC1CCN(C(=O)c2nn(C)c(=O)c3ccccc23)CC1 +CCC1CN(C(=O)NCc2ccc(OC)cc2)CCO1 +COCCNC(=O)CCNC(=O)c1cc(F)cc(Br)c1 +O=C(CN(Cc1cccs1)CC1CCCO1)Nc1nncs1 +CC1(C)CCCN1C(=O)Cc1noc2ccccc12 +O=C(c1cccc(OCC(F)F)n1)N(Cc1ccccc1)C1CC1 +Cc1ccc(CN(C)CC2=NS(=O)(=O)c3ccccc3N2)s1 +CC(CNC(=O)NC(C)Cc1ccc(O)cc1)Cn1cccn1 +Cc1ccc(CC(=O)Nc2ccc(-c3cc[nH]n3)cc2)s1 +O=C1CN(C(=O)COC(=O)c2ccccc2F)c2ccccc2N1 +O=C1COCCN1c1cccc(Br)c1 +COC(=O)c1ccc(NCc2ccc(OC)cc2)nc1 +CCn1nccc1C(=O)Nc1ccc(F)cc1F +Cc1c(C(=O)Nc2cccnc2-n2cccn2)cnn1-c1ccncc1 +CCOc1ccccc1C(=O)Nc1ccc2[nH]ncc2c1 +Cc1cnccc1C1NCCc2c(F)cc(O)cc21 +COCCNC(=O)CNC(=O)Cc1cccc2ccccc12 +COc1ccc(C(=O)CN2CCc3ccccc3C2)cc1OC +Cc1nc(C(=O)N2CCC(N3CCOC(C)C3)CC2)cs1 +Cc1ccc(NC(=O)NCCCN(C)c2ccccc2)cc1C(N)=O +CNC(=O)c1ccccc1C#CCNC(=O)CCC1CCCCC1 +Cc1nn(CCC(=O)Nc2ccccc2C#N)cc1Cl +O=C(NCCNC(=O)c1ccnc2c1OCO2)c1cccc(Cl)c1 +O=C(Cn1cnc2c(oc3ccccc32)c1=O)NCC1CCCO1 +CCCOc1cccc(NCc2ccc(C(=O)N3CCCC3)cc2)c1 +NC(=O)CCN1CCN(C(=O)COc2ccccc2)CC1 +Cc1ccccc1NC(=O)c1ccc2c(c1)nnn2C +CC(=O)c1ccc(C(=O)Nc2ccc3c(C)cc(=O)oc3c2)s1 +CN(C)C(=O)N1CCCn2nc(CNc3cc(C#N)ccn3)cc2C1 +CCOC(=O)CN(C(=O)c1ccc(N)cc1)C(C)C +COc1cccnc1NC(=O)COc1ccccc1C#N +O=C(NCc1ccccn1)c1ccc(NC(=O)C2CC2)cc1 +CCS(=O)(=O)NCCNC(=O)NC(C)c1ccc2ccccc2c1 +Cc1nc(NC(=O)C(C)Sc2nnc(C)n2N)sc1C +C=CCNc1nn2c(=O)c3cc(C)ccc3nc2s1 +CS(=O)(=O)c1ccc(C(=O)NCC2CC=CCC2)cc1 +Cc1ccc(Cc2nnc(NC(=O)Cc3cccs3)o2)c(C)c1 +Cc1[nH]ncc1C(=O)NC(C#N)c1ccc(OCc2ccccc2)cc1 +CC(C)(O)CCc1cccc(C(=O)NCC2(CO)CCOCC2)c1 +Cc1ccncc1NC(=O)NCCC(=O)N1CCCC1 +COc1cc(C)c(C(O)CNC(=O)C2CC2)cc1C +COc1ccc(S(=O)(=O)N2CCCC(C#N)C2)cc1Cl +CCOC(=O)CN(CC)C(=O)c1cn2c(C)cccc2n1 +COC(=O)C1CC(O)CN1Cc1cnc(-c2ccccc2C)s1 +CN(Cc1ccccc1Br)S(=O)(=O)CCCCC#N +O=C(NCC1CCCC1O)c1ccnc(OC2CCC2)c1 +CCC(CC)NC(=O)NCc1ncc(C)c(OC)c1C +NC(=O)Cc1csc(NC(=O)Cc2ccc(C(F)(F)F)cc2)n1 +Cc1cccc(C(=O)N2CC(c3nc(C)no3)C2)c1 +O=C(CCSc1ccccn1)NCCc1cc2ccccc2o1 +CC(C)(C)CC(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +Cc1cc(F)ccc1CCNC(=O)C(C)Sc1ccccn1 +CN(CC1CCCCO1)C(=O)Cn1ncc(N(C)C)cc1=O +O=C(Cn1ccccc1=O)NCCC(c1ccccc1)c1ccccc1 +CCc1ccc(CN2CCN(S(N)(=O)=O)CC2)o1 +O=C(NCC(O)c1ccco1)Nc1nncn1Cc1ccccc1 +Cc1nn(C)c(C(=O)Nc2cnn(C)c2C(N)=O)c1Cl +CC(C)(C)c1cn2nc(N3CCC(C(N)=O)CC3)sc2n1 +CCSc1ccc(NC(=O)N(C)Cc2cnn(C)c2)cn1 +CCNC(=O)CN(CC)C(=O)c1cccc(C)c1O +Cc1ccc2oc(C(=O)N(C)CCc3ccccn3)cc2c1 +COc1cc(CN2CCOC(C#N)C2)c(Br)cc1O +CCc1ccc2nc(Nc3nc(COC)cc(=O)[nH]3)nc(C)c2c1 +Cc1cccc(CNC(=O)CSc2ncnc3sc(C)cc23)c1 +COCCCN(C)C(=O)Nc1ccc(Oc2ncccn2)cc1C +CC(Sc1nccn1C1CC1)C(=O)Nc1ccccc1C#N +Cc1c(N)c(=O)n(-c2ccc(Cl)c(Cl)c2)n1C +NC(=O)c1ccc(SOc2ccc(C(F)(F)F)cn2)cc1 +CC(O)(CNC(=O)C1CCN(S(C)(=O)=O)CC1)C1CC1 +O=C(NCC(O)Cc1ccccc1)Nc1cccc(C(F)(F)F)c1 +Cn1cc(CC2CCN(C(=O)NCc3cn4ccsc4n3)C2)cn1 +Fc1ccc(CSc2nnc(N3CCCC3)n2C2CC2)cc1 +O=C(CC1(Cn2cnnn2)CCCCC1)NCc1ccccc1 +CC(Oc1cccc2ccccc12)C(=O)N1CCC(=O)CC1 +Cc1ccc(C(C)OC(=O)CCNC(=O)c2ccsc2)cc1 +CCOC(=O)c1csc(NC(=O)c2cccc(-n3cccn3)n2)n1 +CCn1c(CCNC(=O)c2ccc(OC)cc2)nc2ccccc21 +Cc1c(N)ccc2nnc(-c3cccc(Cl)c3)n12 +C=C(C)CN(Cc1nc2ccccc2c(=O)[nH]1)C(C)C +O=C(Nc1nnc(-c2ccsc2)o1)c1ccc2c(c1)OCO2 +COC(=O)C(NC(=O)CCn1ncc(=O)c2ccccc21)C(C)(C)C +Cc1cccc(-n2nc(C)c(C(=O)NCc3ccccn3)c2C(C)C)c1 +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1cc2ccccc2[nH]1 +c1ccc(CCc2nc(CN3CCCC4(C3)OCCO4)cs2)cc1 +O=C(C1CC1)N1CCC2(CC1)Nc1cccnc1-n1cccc12 +Cc1ccc(OCC(=O)Nc2ccc3c(c2)C(=O)NCCO3)cc1 +COCCN(Cc1cnn(C)c1)C(=O)c1cnc2ccccc2n1 +O=C(Nc1cccnc1)C1CCN(C(=O)c2cccc3ccoc23)CC1 +O=C(OCCO)C(O)(c1ccccc1)c1ccccc1 +CCn1c(SCCc2ccccc2)nc2c1c(=O)n(C)c(=O)n2C +N#Cc1ccc(N2CCC(NC(=O)C3CC3)CC2)c(F)c1 +Cc1cccc(C(CNC(=O)OC(C)(C)C)N2CCOCC2)c1 +Cc1noc2nc(C(C)C)cc(C(=O)Nc3cnn(C)c3)c12 +COc1ccccc1-n1c2c(cc(C#N)c1=O)C(=O)CCC2 +O=C(NC1CC1)c1ccc(NC(=O)C2Cc3ccccc3S2)cc1 +CC1CC(C)CN(C(=O)CN2C(=O)CCCc3ccccc32)C1 +CC(C)c1nc(C2CCCN(C(=O)COC3CCCCC3C)C2)no1 +OCc1nc2ccc(Oc3ccc4nc(CO)[nH]c4c3)cc2[nH]1 +CCN(CC(=O)NC)C(=O)c1sccc1Br +CN(CC12CC3CC(CC(C3)C1)C2)c1cn[nH]c(=O)c1Cl +c1ccc2nn(CCn3nc4ccccc4n3)nc2c1 +CCc1noc(C)c1C(=O)NCc1nc2ccccc2n1C +CCOC(=O)C1=C(C(C)C)NC(=O)NC1c1c[nH]c2ccccc12 +CCn1c(CNC2CCSc3ccc(F)cc32)nc2ccccc21 +CC(C)(C)c1cc2ncc3c(n2n1)CC1CCC3N1 +Cc1ccc2nnc(C#N)c(NCc3ccccn3)c2c1 +Cc1nc(SC(C)C(F)(F)F)n(CC2CCCO2)c1C +COCCOCC(=O)N1CCN(c2ccc(OC)cc2)C(=O)C1C +CCN(Cc1cccc(C)c1)C(=O)CNC(=O)c1ccsc1 +O=C(NCC(O)c1ccsc1)Nc1nc2ccc(Cl)cn2n1 +Cc1csc(NC(=O)c2ccc(NC(=O)NC3CC3)cc2)n1 +O=C(Nc1cccc(Cl)c1-n1cncn1)c1ccncc1 +Cc1ccccc1NCC(O)COc1ccccc1F +O=C(c1ccc(-n2cncn2)cc1)N1CCN(c2nccs2)CC1 +CCOc1ccccc1C(C)OC(=O)c1cnc2ccccn2c1=O +CC(=O)N1CC=C(c2c(C)[nH]c3ccccc23)CC1 +O=C(CSc1nncs1)Oc1cc(Cl)cc(Cl)c1 +COc1ccc(Cl)cc1NC(=O)C(C)CC#N +CCc1nc2cc(C(=O)CCN3CCOCC3)ccc2[nH]1 +Nc1c(NCc2cccnc2)ncnc1N1CCCC1 +CN(C)C(=O)Cc1ccc(NC(=O)NC2CCCCCC2)cc1 +COc1ccc(-c2nnsc2C(=O)N2CCOCC2)cc1 +CC(=O)Nc1cccc(NC(=O)COc2ccc(Cl)cc2)c1C +CC(=O)Nc1cc(Cl)ccc1NC(=O)Cc1cccc(C)c1 +O=C(NC1CCCC(C(F)(F)F)C1)c1ccsc1 +Cc1cccc(NC(=O)CSc2cc(N3CCCC3)ncn2)c1 +Cn1cc(CCCC(=O)NCc2cccnc2)c2ccccc21 +O=S(=O)(NCCc1ccoc1)c1cc(F)ccc1F +CC(C)(CNC(=O)N(CC1CCOC1)C1CC1)c1ccncc1 +Cc1cnn(C)c1C(=O)Nc1nc2c(F)cc(F)cc2s1 +O=C(CCNc1ccc(Cl)c(Cl)c1)NC1CC1 +CN(C)S(=O)(=O)c1ccc(SCc2ccccc2C#N)nc1 +COc1ccc(-c2ccc(C#N)c(=O)n2CC(C)C#N)cc1 +O=C(CCn1cc(Br)cn1)NCc1ccc(Cl)cc1 +O=C(Cn1nnc(-c2ccccc2)n1)Nc1ccc2cn[nH]c2c1 +CC(=O)c1cnc(Nc2nc(C)c3cccc(C)c3n2)nc1C +CCc1nc2cc(NC(=O)CCC(=O)Nc3nccs3)ccc2o1 +CSc1nc(C)cc(C(=O)NCc2ccccn2)n1 +CSc1ccc(COC(=O)CNC(=O)c2ccc(C)cc2)cc1 +CN(CCc1ccccn1)c1cncc(-n2cccn2)n1 +Cc1n[nH]c(C)c1NC(=O)CN1CCOC(Cn2cccn2)C1 +O=C(Cc1ccc(F)cc1F)NCCCc1nnc2n1CCCCC2 +COc1ccc(N)cc1C(=O)OCCC(C)(C)C +CC(C)C(=O)NC1CCCN(C(=O)c2cc3ccccc3cc2O)C1 +COC(=O)c1ccccc1C(=O)Nc1ccccc1S(C)(=O)=O +COc1ccc(NC(=O)Cn2c(C)cc(=O)c3cccc(F)c32)cc1 +CCc1onc(C)c1NC(=O)NCC(O)C(CC)CC +CCOC(=O)CCN1C(=O)C(CC)Oc2cccc(N)c21 +Cc1ccc(CC(NC(=O)C(C)n2cccn2)c2ccccn2)cc1 +CCc1onc(C)c1NC(=O)CCc1nc2c(F)cccc2[nH]1 +Cn1c(CN2CCCC2Cc2ccccc2Cl)cc(=O)n(C)c1=O +CC(C)CCNC(=O)c1ccc(CN2CCOCC2)cc1 +CC(=O)N1CCNCC1C(=O)N1CCC(c2ccc(C)cn2)CC1 +CNC(=O)COC1COC2(CCN(C(=O)COC)C2)C1 +CC(=O)Nc1cc(S(=O)(=O)NC2CCCCC2C)ccc1F +CCCCN(CC)C(=O)c1cccc(OC)c1OC +Cc1nc(-c2nc[nH]n2)sc1C(=O)NCC(C)(C)c1ccncc1 +CC(=O)c1ccc2nc(-c3ccccc3)n(C)c2c1 +CC(NC(=O)NCCNC(=O)c1ccc(F)cc1)c1ccccc1 +Cc1cc2c(cc1S(=O)(=O)Nc1ccccc1)OCC(=O)N2 +CN(C)C(=O)CNc1cccc(C(=O)NCc2ccccc2)c1 +Nc1c(Nc2ccccc2F)ncnc1-n1nnc2ccccc21 +CCc1cccc(C)c1NC(=O)CNc1cccc(F)c1 +O=C(c1cc[nH]n1)N1CCC(OCCCc2ccccc2)C1 +Cc1cc(NC(=O)c2ccncc2)c(=O)n(Cc2ccc(F)cc2)c1 +O=C(C1CC2CN(CC3CC3)CC1O2)N1CCCC1 +COc1cccc(C(=O)OCC(=O)Nc2cccc(F)c2)c1OC +CCn1nnc(S(=O)(=O)c2ccc(C)cc2)c1N +CC(Sc1ccccn1)C(=O)Nc1ccc2oc(C3CC3)nc2c1 +CN(CC(=O)NC(C)(C)C)C(=O)c1ccc(Cl)cc1 +Cn1nc(C2CCCN(C(=O)C3CCCC3)C2)c2nccnc21 +CC(=O)c1ccc(Cl)c(NC2CCC(O)CC2)c1 +CCOc1ccccc1OCC(=O)NCc1ccc(C)cc1 +Cc1cccc(OCCN(C)C(=O)c2ccc(=O)n(C)n2)c1 +FC(F)n1ccnc1CCNCc1csc(-c2cccs2)n1 +CN1CC2(CCN(C(=O)c3cnc(C4CC4)[nH]c3=O)CC2)OC1=O +COc1ccccc1N1CC(C(=O)NC(C)C)CC1=O +CCc1noc(CC)c1CNC(=O)Nc1ccc2[nH]nnc2c1 +NC(=O)C1CN(CC(O)COc2ccc3ccccc3c2)CCO1 +O=C(Oc1ccc(F)cc1)C1CCN(c2cnccn2)CC1 +Cc1cc(CNc2nncc(-c3ccccc3C)n2)on1 +CCN(CC)C(=O)Cn1nc(C#N)cc1-c1ccncc1 +Cc1cc2c(c(C(O)c3ccc(F)cc3)c1)NC(=O)C2C +O=C(Nc1ccc2ncccc2c1)c1ccnc(OC2CCC2)c1 +CNC(=O)Nc1cccc(NS(=O)(=O)c2cn[nH]c2)c1 +N#Cc1ccc(-c2ccncc2)n2nc(-c3ccccc3F)nc12 +Cc1ccsc1CN(Cc1cccc(O)c1)Cc1ccccn1 +Cc1ccccc1NC(=O)N1CCC(NS(C)(=O)=O)CC1 +O=C(Nc1ccc(Cl)cc1)Nc1cccc(CO)n1 +Cc1nc(N(C)C)sc1CN1CCC(OCCCO)CC1 +Cc1nn(-c2ccccc2)c(C)c1NS(=O)(=O)C1CCCC1 +CC1CCC(OC(=O)CCNC(=O)c2cccs2)CC1 +Cn1cnc2cc(OC(=O)c3ccc(Cn4ccnc4)cc3)ccc21 +CCN(CC(C)C#N)C(=O)CSc1ccccc1 +O=C1CCCN1CC(=O)N1CCc2[nH]nc(-c3ccccc3F)c2C1 +O=C(NCC1CC1)c1ccc(OCC(F)F)nc1 +O=C(Nc1ccccc1-c1nc(-c2cccnc2)no1)c1ccncc1 +CCOCCCNc1nc(C)nc2c1Cc1ccccc1OC2 +O=C(c1ccccc1F)N1CCN(Cc2ccc(Cl)cc2)CC1 +COc1ccc2c(c1F)C(c1ccc(C#N)cc1)NCC2 +COCc1c(C(=O)N2CCc3c(nc(N(C)C)[nH]c3=O)C2)noc1C +COc1ccc(C(C)NC(=O)C2CC=CC2)cc1OC +CC(NC(=O)c1cnn2c(-c3ccccc3)ccnc12)c1ccccc1 +COC(=O)C(C)C(O)c1cc(Br)c2c(c1)OCCO2 +O=C(Nc1ccccc1F)c1cn(Cc2ccccc2)nn1 +CSc1nsc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)n1 +COc1ccc(NC(=O)c2cccc(NC(N)=O)c2)cc1 +O=C(c1scnc1C1CC1)N1CCC(c2ccn[nH]2)CC1 +O=C(NCc1ccnc(OC2CCC2)c1)C1CCCCCC1 +CCn1c(C)cc(NCCc2ccccc2)cc1=O +Cc1ccoc1C(=O)N(Cc1ccccc1)CC(C)CO +COc1ccnc(NC(=O)c2ccc(Cl)c(Cl)c2)c1 +CC1CN(C(=O)c2nn(-c3ccccc3)c3c2CCC3)CC(C)O1 +CCC(C)C(=O)Oc1cccc(N2CCCC2=O)c1 +Cc1nn(C(C)C)c(C)c1NCc1cc(Br)cs1 +CCc1cc2c(=O)n(CC(=O)c3cc(C)n(CC)c3C)cnc2s1 +CCCN(CC(=O)OC)C(=O)c1sccc1C +COC(=O)C1CCC(NC(C)=O)C(C(=O)OC)C1 +CCOC(=O)C1CCCN(C(=O)N(CC)CC)C1 +CN(C)C(=O)CN(C)S(=O)(=O)c1cccc(F)c1 +Cc1nccn1Cc1cccc(CNC(=O)c2cccc3[nH]nnc23)c1 +Cc1noc(C)c1CNc1ccc2c(C)cc(=O)oc2c1 +Nc1cc(S(=O)(=O)N2CCCCCC2)ccc1F +CC(C)C(=O)N1CCCC(c2cc3[nH]c4c(c(=O)n3n2)CCCC4)C1 +Cc1cc(C)c(CN2CCC(O)(c3ccccc3)C2)o1 +CC(C)Oc1ncccc1CNc1cn[nH]c(=O)c1Cl +Cc1ccccc1C1CC1C(=O)Nc1ccn(CCc2ccccn2)n1 +O=C(Nc1nc(CN2CCOCC2)cs1)c1ccc2c(c1)CCO2 +Cc1ccc(NC(=O)COC(=O)Cc2c(C)noc2C)cc1C +Cc1ccc2c(c1)C(Nc1ccc(F)cc1C)C(=O)N2 +CCCCC(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1 +CC1CN(C(=O)c2csc(-c3ncccn3)n2)CC(C)O1 +O=c1[nH]cnc2ccc(Br)c(Cl)c12 +N#Cc1cn(C2CC2)c(=O)n(Cc2noc(-c3ccoc3)n2)c1=O +CCOC(=O)CNc1c(C)n(C)n(-c2ccccc2)c1=O +CCC1CN(C(=O)c2n[nH]c3ccccc23)CCO1 +COc1ccc(F)cc1C(=O)NCCNc1ncccn1 +Cc1nc(CNC(=O)NC2CCCC(C)C2)oc1C +Cn1cc(CC2C(OCC3CC3)CCN2Cc2nccs2)cn1 +CCc1cc2c(NC)nc(-c3cccnc3)nc2s1 +Cn1ncc(-c2ccc3c(c2)OCO3)c(CO)c1=O +C1=C(c2cccnc2)Nc2nnnn2C1c1cccs1 +Cc1cccc(C(CNC(=O)c2n[nH]c(=O)[nH]2)N2CCOCC2)c1 +Cc1cc2c(=O)n(C)c(SCC(=O)Nc3ccccc3)nc2s1 +CN(Cc1ccccn1)C(=O)NCC1CCN(c2ccc(F)cc2)C1 +Cc1ccc(OCCCC(=O)NC2CCCC2CO)cc1C +CCCCN(CC(=O)N1CCNCC1)S(=O)(=O)c1cccs1 +CNC(=O)NC(C)(C)C(=O)N1CCc2sccc2C1 +Cc1cc(F)ccc1NC(=O)C(C)NS(=O)(=O)c1cnn(C)c1 +O=C(Cn1nnc(-c2ccc3c(c2)OCO3)n1)NCc1ccccc1 +Cc1csc(NC(=O)c2cccc(OCc3c(C)noc3C)c2)n1 +CN(CC(F)(F)F)C(=O)c1cccc(Br)c1 +Cn1nnnc1SCc1ccc(Br)cc1F +Cc1cc(NCc2c(C)nn(C)c2C)n2ncnc2n1 +CCN(Cc1cnc2ccccn12)C(=O)Nc1ccc2c(c1)OCO2 +O=C(CCCN1CCOC1=O)NCc1ccc(-n2cccn2)cc1 +CCNC(=O)c1cc(Cl)ccc1NCC(=O)OC +Cc1cc(C2CCCN2C(=O)Nc2cccc3cccnc23)no1 +CCCNC(=O)CCC(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +CC(C#N)CN(C)C(=O)CN(C)c1ccc(C#N)cn1 +CCOc1ccc(F)c(C(=O)NC(C)(CC(C)C)C(N)=O)c1F +Nc1ccc(S(=O)(=O)NCCc2ccccc2Cl)cc1 +CCN(CC)c1ccc(-n2ccnc2-c2cccc(O)c2)cn1 +Cc1c(NCc2cnn(-c3ccccc3)c2)cccc1C(N)=O +Nc1ccc(SCC(=O)Nc2ccc(S(N)(=O)=O)cc2)nc1 +COc1ccc(CC(=O)NCc2nc(-c3ccco3)n[nH]2)cc1 +Cn1nccc1C(=O)OCC(=O)Nc1ccc(F)c(Cl)c1 +CCc1ccc(CNc2cccc(-c3n[nH]c(C)n3)c2)o1 +CS(=O)(=O)N(CC(=O)Nc1cccc(Cl)c1)c1ccccc1 +CCOC(=O)NCC#CCOc1ccc2c(c1)OCO2 +CCS(=O)(=O)NCCCNC(=O)c1sccc1C#N +Cc1ccc(C(=O)NCC(=O)Nc2cccc(-n3cnnc3)c2)cc1C +Cc1nccn1-c1ccc(CNC(=O)c2scnc2C2CC2)cn1 +CCCCn1c(SCc2cccc(F)c2)n[nH]c1=O +CNC(=O)c1cc(OC2CC2)cc(C(=O)N(C)C)c1 +COc1ccc(-c2csc(CNC(=O)Cc3cccs3)n2)cc1 +CC(C)CC(=O)N1Cc2ccccc2CC1C(=O)Nc1nccs1 +Cc1csc(=O)n1CC(=O)N1CCN(c2ccccc2F)CC1 +Cn1cc(C(=O)NCC2(C3CC3)CC2)c(C(C)(C)C)n1 +COCC(C)N1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +O=C(Cc1c(F)cccc1Cl)NCCCN1CCCCCC1=O +CC(NC(=O)c1nc2ccccc2[nH]1)c1ccc2c(c1)CC(=O)N2 +CCc1ccc(Cn2nnc(C(=O)Nc3ccccc3)c2N)cc1 +COc1cc(Cl)c(C)cc1NCCCCCO +COc1ccc(C(=O)NC(C)(C)C(N)=O)cc1Br +CCOC(=O)c1sc2cccc(F)c2c1COC +CCOC(C)C(=O)Nc1sc(-c2ccccc2)nc1C +Cc1cccc(-n2ccnc2SC2CCCCC2=O)c1 +N#CCCN(C(=O)COc1ccccc1C#N)c1ccccc1 +CC(=O)c1cccc(S(=O)(=O)NCc2ccc3ccccc3c2)c1 +Cc1nnc(SC2CCCCNC2=O)n1CCc1cccs1 +O=c1ccc2c(n1CC1CCOCC1)CCC(NCc1ccoc1)C2 +CNc1[nH]c2c(c(=O)c1N)c(=O)n(C)c(=O)n2C +COCCCC(=O)N1CCN(CC(C)(C)O)CC1 +CC1CN2CCCC2CN1S(=O)(=O)CC1CCCO1 +O=C(Nc1ccc(Cl)cc1Cl)c1ccon1 +CCCn1c(C)nnc1SCc1nnc(C)n1CC +Cc1c(C(=O)n2ncc(-c3cccc(Cl)c3)c2N)cnn1C +COC(=O)c1ccsc1NC(=O)CCc1c[nH]c2ccccc12 +CCc1ccccc1NS(=O)(=O)c1ccc(O)cc1 +CCc1noc(CC)c1CNC(=O)CCNC(N)=O +c1cncc(CSc2nnc(N3CCCCC3)n2C2CC2)c1 +COc1ccc(F)cc1NC(=O)CC1CN(C(=O)OC(C)(C)C)C1 +Cc1ccc(C(=O)NC(C)c2noc(Cc3ccccc3)n2)s1 +Cc1cc(NC(=O)c2cnc3onc(C)c3c2)n(C)n1 +COc1cccc(NC(=O)COC(=O)c2ccc(C)nc2)c1 +N#CCCC(C#N)CSc1nnc(-c2ccncc2)n1C1CC1 +CNC(=O)CCCC(=O)c1cc(C)c(OC)cc1C +COc1cc(OC)cc(C(NC(=O)C2CC=CC2)c2nccn2C)c1 +Cc1cccc(C(=O)Nc2ccc(C(=O)c3nccn3C)cc2)n1 +CC(N)C(=O)c1ccc2[nH]c(-c3ccccc3)nc2c1 +O=C(NCC1CCOC1)c1ccc(CS(=O)(=O)c2ccccc2)o1 +CCCNC(=O)c1cc(O)c2cc(OC)cc(OC)c2c1 +Cc1cccc(C(=O)Nc2cccc(-c3ccnc(C)n3)c2)n1 +CC1CC(C)CN(S(=O)(=O)N(Cc2ccncc2)C2CC2)C1 +CCN(CC)C(=O)NCc1cccc(Cn2ccnc2)c1 +O=C(NCc1ccc2c(c1)OCO2)c1csnn1 +COc1cc(NC(=O)c2c(C)nn(C)c2C)cc(OC)c1OC +COC1CCC(CC(=O)Nc2ccccc2-n2cnnn2)CC1 +COc1ccc(OC)c2c1CC(c1cccs1)CN2 +O=S(=O)(NCCc1c[nH]c2ccc(F)cc12)c1ccc(F)cc1 +O=C(NCc1ccccn1)c1nc2ncc(Br)cn2n1 +Cc1nc(C)c(C(=O)NCc2cc(Br)ccc2F)s1 +Cc1nc(C)c(C2NCCc3ccc(F)cc32)s1 +Cn1c(SCC(N)=O)nnc1-c1ccc(O)cc1 +CCNC(c1cc2c(cc1Cl)OCCO2)C(F)(F)F +CCC(CO)NC(=O)c1ccc(Cn2cccn2)o1 +CCN(Cc1cccs1)C(=O)c1ccc(CNC(N)=O)cc1 +C=CCN1C(=O)C(C)NC12CCN(C(=O)c1ccc(C)cc1)CC2 +Cn1cc(S(=O)(=O)NC2CCN(CC(F)(F)F)C2)cn1 +O=C(CCc1ncc(-c2ccc(Cl)cc2)o1)NCc1ccco1 +O=C(CCC(=O)c1ccc2c(c1)CCC2)Nc1cccc(F)c1 +CC1CCN(c2nnc(SCCO)n2CC2CCCO2)CC1 +CN(CCOCC1CC1)C(=O)C1CCCN1C(=O)c1cccs1 +Cc1ncsc1CCC(=O)NCC1CCc2ccccc2O1 +COCCOc1ccc(CNc2ccc(F)cc2)cc1 +Nc1ncc2c(n1)CN(CCc1ccc(Cl)cc1)C2=O +C=CCC1CC=CC(c2ccccc2)N1C(=O)c1cc(C)n[nH]1 +C#CCN(Cc1ccco1)C(=O)Nc1cccc(-c2nccs2)c1 +CCCCCCNC(=O)N1CCN(C(=O)N(C)C)CC1 +Cc1nn(CC(=O)Nc2ccc(C#N)cc2)c(=O)c2ccccc12 +O=S(=O)(c1c(F)cccc1F)N1CCSc2ccccc21 +O=C(c1cnc(-c2cccnc2)nc1)N1CCc2nc[nH]c(=O)c2CC1 +Cn1cnnc1C1CCCN(C(=O)CCCc2cccs2)C1 +CN(C)C(=O)c1cc2c(s1)CCN2C(=O)c1ccc(F)cc1 +Cc1ncc(CNC(=O)c2cccc(C)c2O)s1 +Oc1cc(F)c2c(c1)C(C=Cc1ccncc1)NCC2 +COCC(=O)NC(C(=O)NCC(F)(F)F)C(C)C +CCN(CCC(=O)OC)Cc1cc(C#N)cs1 +Cc1ccc(N2CC3(CCN(C(=O)C4CCOCC4)C3)CC2=O)s1 +CCC(=O)N1CCCC(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)C1 +NC(=O)n1c(C2CCCCC2)nn(-c2ccccc2)c1=O +CCOc1cc(C(=O)Nc2ccc(C)cc2O)ccc1OC +Brc1cnc(Oc2cccc(-n3cncn3)c2)nc1 +CCOC(=O)c1sc(NC(=O)CCOC)cc1C +CC(=O)c1ccc2[nH]c(Cc3ccccc3)nc2c1 +CCN(CC)C(=O)CCC(=O)Oc1c(C)nn(C)c1C +CC(=O)c1cccc(NC(C)C(=O)NC(C)(C)C)c1 +COCCCCNC(=O)NC1CCc2cc(Cl)ccc21 +O=C(CCn1ccccc1=O)NCc1cccnc1 +Cn1c(CNC(=O)c2ccc3ccccc3n2)nc2ccccc21 +COC(=O)c1cc(C)sc1NS(=O)(=O)c1cn(C)nc1C +COc1cc(-c2nc(-c3ccncc3)cs2)ccc1N +Cc1cc(NC(=O)C(C)Nc2ccc(N3CCCC3=O)cc2)no1 +Cn1ncc2c1C(COCC1CC1)CN(c1ncc(F)cn1)C2 +OC1c2ccccc2OCC1N1CCc2ccccc2C1 +O=C(CCc1cccc(OC2CCCC2)c1)Nc1nc[nH]n1 +CC(C)NC(=O)CCS(=O)(=O)c1ccc(Br)cc1 +O=c1[nH]c(N2CCCC2)nc2nccc(-c3ccccn3)c12 +Cc1cccc(C)c1NCC(=O)NCCc1ccc2c(c1)OCO2 +CCOC1CCN(C(=O)CCc2ccccc2C)C2CCOC12 +COc1ccc(CC(C)N(C)Cc2nc3c(cnn3C)c(=O)[nH]2)cc1 +CC(C)NC(=O)NCCn1nc(-c2ccccn2)n(C)c1=O +CCc1ccc(S(=O)(=O)Nc2cc(C)[nH]c2C(=O)OC)cc1 +COc1cc(C)c(S(=O)(=O)Oc2ccccc2NC(C)=O)cc1C +CC1Oc2ccccc2N(CC(=O)Nc2ccc3c(c2)OCO3)C1=O +COc1cc(C#N)ccc1OCC(=O)NC(C)c1ccncc1 +CCNS(=O)(=O)c1ccc(CCC(N)=O)cc1 +CCOC(=O)C1CCCN(C(=O)c2cccc(N3CCCC3=O)c2)C1 +COc1cc(C)c(C(C)NC(=O)c2c(C)oc(C)c2C)cc1OC +Cc1ccc2oc(C3CC(=O)N(c4ccccc4)C3)nc2c1 +C=CCN1C(=O)COC2(CCN(C(=O)c3ccc[nH]3)CC2)C1C +CCc1nc(C)c(C(=O)N2CCCC2c2nc3ccccc3s2)o1 +Fc1cccc(OC2CC3CN(Cc4ccncc4)CCN3C2)c1 +CCOC(=O)C1CCN(C(C)C(=O)c2cccs2)CC1 +CC(C)c1c(O)nc(SCC(=O)Nc2ccccc2F)[nH]c1=O +O=C(Nc1ccc(-c2nnc3n2CCCCC3)cc1)c1ccc(=O)[nH]c1 +O=C(CCc1ccc(=O)[nH]n1)NCC1C2CC3CC(C2)CC1C3 +Cc1cc(F)ccc1NC(=O)NCc1ccnc(OC2CCC2)c1 +Cc1cncc(C2CCCN(C(=O)c3ccncc3)C2)n1 +COc1ncccc1CNC(=O)Nc1ccc2c(c1)n(C)c(=O)n2C +COc1cc(COC(=O)c2ncoc2C2CCCO2)ccc1C +CCOc1cc(F)ccc1NS(=O)(=O)c1ccccc1OC +COc1cc(CN(C)Cc2ccc(C#N)cc2)cc(OC)c1 +Cc1cccc(CC(=O)NS(=O)(=O)N2CCc3ccccc3C2)c1 +O=C(COc1ccc(F)cc1)Nc1nnc(C2CCCCC2)s1 +CC1(C)OCC2(CO1)CN(C(=O)Nc1ccccc1C(F)(F)F)C2 +FC(F)(F)c1cc(NCc2nnc3n2CCC3)c2ccccc2n1 +Cn1c(SCCC(=O)Nc2ccccc2C#N)nnc1C1CC1 +Clc1cccc(Cl)c1Cn1nnc(N2CCCCC2)n1 +CNC(=O)c1sc(Cc2cccc(C)c2)nc1C +Cc1cc(NC(=O)c2ccc(=O)n(Cc3ccccc3)n2)ccn1 +COC1CCCCC1OC(=O)c1cccc(NC(=O)NC2CC2)c1 +CCc1noc(C(C)N2CCN(c3ccccc3O)CC2)n1 +CC(C(=O)NCC(=O)C(C)(C)C)n1ccc(C(F)(F)F)n1 +CCC(NC(=O)c1ccccc1F)c1cccc(Cl)c1 +Cc1cc(=O)n(C(C)C(=O)NCc2ccco2)c2c(C)cccc12 +O=C(Cc1c[nH]c2ccccc12)N1CCC(Oc2ccccc2)CC1 +CCSc1nnc(SCCn2nc3ccccn3c2=O)s1 +O=C(C1CCc2ccccc21)N1CCN(C2CCCC2O)CC1 +Cc1ccc(-c2nnn(CC(=O)Nc3ccc(F)cc3)n2)cc1 +O=S(=O)(c1ccc2c(c1)CCCN2)N1CCCC1 +Cc1ccc(C(O)CNC(=O)NCc2ccc(F)cc2)o1 +Cn1c(C(=O)c2ccccc2)nc2ccc(O)cc21 +CCOc1ccc(-c2cc(C(N)=O)nc(N)n2)cc1 +CN(CC1CC1)C(=O)NCCCN(C)c1ccccc1 +O=C(COc1ccccc1)NC1C(c2cncnc2)CC(O)C1O +CCCCc1nnc(NC(=O)C(C)Sc2nc(C)n[nH]2)s1 +CCS(=O)(=O)N1CCc2cc(-c3csc(NC)n3)ccc21 +C=CCN1CCN(c2cccc(S(C)(=O)=O)c2)C1=O +CCOc1ccccc1OCC(=O)NC1CCCCCC1 +CCCn1c(C)nnc1SCc1ccn(-c2ccc(F)cc2)n1 +CC(C)CN(C)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +O=C(Nc1ccc(Cl)cc1)C1CC(=O)N(C2CC2)C1 +CC(OC1CCCC1)C(=O)Nc1ccc(CC(N)=O)cc1 +CCCC(=O)Nc1nnc(SCC(N)=O)s1 +C#CCNc1cccc(CS(=O)(=O)c2ccccc2)c1 +FC(F)(F)c1ccc(N2CCN(Cc3cccnc3)CC2)nc1 +CCc1nc2c(c(C(=O)NCC3CCCO3)n1)OCO2 +O=C(Nc1ccccc1Cl)Nc1cc(C(F)(F)F)c[nH]c1=O +O=S(=O)(Nc1cnn(C2CCOCC2)c1)c1ccc(Cl)cc1 +COc1cccc(CS(=O)(=O)NC2(c3ccccc3)CC2)c1 +COc1cc2oc3cc(OC)c(OC)cc3c2cc1OC +CC(C)n1nccc1NC(=O)NC(CO)c1cc(F)c(F)c(F)c1 +O=C(Cn1c(C2CC2)nc2ccccc21)Nc1cccc(F)c1 +COCCOc1ccc(NC(=O)c2cccc(C)c2)cc1 +O=S(=O)(NCC1CCCCO1)c1ccccc1Br +Cc1ccc(NC(=O)CSc2nc3c(c(=O)[nH]2)CCC3)cc1C +CC(C)Cc1c(CO)nnn1-c1ccc(Cl)cc1 +Cc1nc(CC(=O)NC(C)CCn2cccn2)cs1 +CCOC(=O)CN(C)C(=O)Cc1csc(-c2cccc(F)c2)n1 +COc1cc(C)c(-c2nc3c(cnn3C(C)C)[nH]2)c(OC)c1OC +Cc1cc(C(=O)N(CCc2cccs2)Cc2cccnc2)c(C)o1 +COCCn1cc(C(=O)N2CC(C)(C)C2c2ccccc2)ccc1=O +Nc1ccc(-c2ccc(N3CCCCCC3)nn2)cc1 +CCn1nc(C)c(CCC(=O)NCC2CCCO2)c1C +COc1ccc(F)cc1C(C#N)Cc1cccc(C#N)c1 +COc1ccc(C(=O)Nc2ccc(CCC(=O)N(C)C)cc2)cc1 +CCCN1C(=O)CCc2cc(NS(=O)(=O)CC(C)C)ccc21 +CCc1nc(CN(C)C(=O)C2CCCN2C(=O)C2CCCCC2)no1 +COc1ccnc(NC(=O)CCn2c(=O)oc3ccccc32)c1 +CC(=O)NCC(=O)N1CCCC1c1ccc(F)cc1 +CC1COCCN1C(=O)c1cc(-c2ccco2)on1 +Cc1c(C(=O)Nc2ccc(N(C)C)nc2)cnn1-c1ccccc1 +CC1(C)CN(C(=O)c2cccc(NC(=O)C(C)(C)C)c2)CCO1 +O=C(CSc1ccccc1)NCC1CN2CCCC2CO1 +O=C(NCc1ccccn1)NCc1ccccc1OCC(F)(F)F +CCCC1CN(C(=O)C(C)Oc2ccc(OC)cc2)CCO1 +Cc1cc2ncn(C(=O)CCNC(=O)c3ccccc3)c2cc1C +Cc1cc(C(=O)N2CCc3sccc3C2)nn1C(C)(C)C +COc1cc(C)ccc1OCCC(=O)N1CCC(C)CC1C +Cc1ccc2nc(C3CC3)cc(-c3nc(-c4cnccn4)no3)c2c1 +CN(CC1CC1)C(=O)COc1cccc(C(F)(F)F)n1 +Cc1ccc(N2CCCN(Cc3cccn3CCC(C)C)CC2)nn1 +Cc1nc2c(c(=O)[nH]1)CCN(Cc1ccccc1F)CC2 +COc1cc(Cl)ccc1CNC(=O)Nc1cn[nH]c1 +O=C(c1ccn2cncc2c1)N(Cc1cccs1)CC1CCCO1 +Cn1c(C(=O)NCc2ccccn2)cc2c(=O)oc3ccccc3c21 +CC1CCC(NC(=O)NCCCc2nnc3n2CCCCC3)C(C)C1 +Cc1cc(CNC(=O)Nc2ccc(Cl)c(C#N)c2)on1 +COc1cccc(CC(=O)Nc2cccc(F)c2C#N)c1 +O=C(CC1CCCC1)Nc1cccc(CN2CCOCC2)c1 +Cc1ccc2c(c1F)C(C(O)c1ccccc1)NCC2 +CCc1nc(CN(C)C(=O)C2(c3ccc(C)c(OC)c3)CC2)cs1 +O=C(CN1CCN(C(=O)c2ccco2)CC1)c1cccs1 +COc1ccccc1-n1cnnc1SCc1ccnc(N(C)C)c1 +CC(NC(=O)c1nc2ccccc2c(=O)[nH]1)c1ccncc1 +CC(NC(=O)Cn1cnnn1)c1ccc(N2CCCC2=O)cc1 +CCn1cc(C(=O)Nc2cccc(C(C)OC)c2)cn1 +CC(C)c1csc(-c2ccc(CNC(=O)c3ccnn3C)cc2)n1 +Cn1c(=O)ccn(CC(=O)OCC(F)(F)F)c1=O +O=C(CCc1ccc2nc[nH]c2c1)NCc1cc(F)cc(F)c1 +O=C(COc1ccccc1O)NC1CC2C(=O)NCC(=O)N2C1 +CCC(C)n1ncc(C(=O)Nc2cccc(F)c2)c1C1CC1 +CCN(CC1CCOC1)C(=O)c1ccc(N2CCOCC2)c(F)c1 +Cc1[nH]ncc1CCCNC(=O)N(C)Cc1cc(F)c(F)c(F)c1 +Cn1c(C2CC2)nc2cc(NC(=O)C3CC3(C)C)ccc21 +Cc1ccccc1NC(=O)C(C)n1cnc2oc(C)c(C)c2c1=O +Cc1ccc(CN(C)S(=O)(=O)N2CC(C)OC(C)C2)s1 +O=C(Nc1ccc2c(c1)COC2)N(Cc1ccccc1)C1CC1 +COC(=O)N1CCC(NC(=O)c2ccc3cc[nH]c3c2)CC1 +c1cncc(CN(c2ccc3nnnn3n2)C2CC2)c1 +Cc1ccc(N2CC(C(=O)NCCC3=CCCCC3)CC2=O)cc1 +COC(=O)c1c(CC(=O)N2CCCC2(C)C)[nH]c(C(C)=O)c1C +CC(C)C(=O)N1CCC(c2nc(O)cc(-c3ccccn3)n2)CC1 +COC(=O)c1cc(-c2cc(N)c(OC)cc2OC)on1 +Cc1ccc(S(=O)(=O)NC(C)(C)C)cc1C(=O)NC1CC1 +N#Cc1cccc(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)c1 +O=C(C1CCC1)N1CCN(c2ccccc2Cl)CC1 +CC1CN(C(=O)c2ccc(NC(=O)C3CC3)cc2)c2ccccc2O1 +Cc1cc(=O)[nH]cc1C(=O)N1CCC(Oc2cccc(Cl)c2)C1 +COc1ccc(CNc2nccn(Cc3ccc(F)cc3)c2=O)cc1 +O=C(NCc1cc(F)cc(F)c1)c1cn[nH]c1-c1ccc(Cl)cc1 +O=C(Cc1ccc(CO)cc1)N1CC(Oc2ccccc2F)C1 +C=CCOc1cccc(NC(=O)N(C)CC2CC2)c1 +COc1cc(C)sc1C(=O)NCc1nc(-c2cccs2)no1 +C=CCNS(=O)(=O)c1ccc(N2CCCCS2(=O)=O)cc1C +CC(=O)Nc1cc(C(=O)NCc2ccc3c(c2)OCO3)ccc1C +Cc1nc(Sc2nnnn2C)c2c3c(sc2n1)CCC3 +Cc1occc1C(=O)NCC(=O)NC1CCc2c(O)cccc21 +NC(=O)c1ccc(NC(=O)COc2ccc3ccc(=O)oc3c2)cc1 +NC(=O)c1csc(C(=O)Nc2cccc(F)c2)c1 +CC(NC(=O)Cn1cnnn1)c1cccc(OC(F)F)c1 +COc1ccc(C2CCCN2C(=O)c2cc(C)on2)cc1 +C=CCCC(=O)N1CCCC1C(=O)Nc1cccc(-n2cccn2)c1 +O=C(NCc1ccco1)c1cc2cc(Br)ccc2o1 +COc1ccccc1CC(=O)N1CCN(c2ccccc2C)C(=O)C1 +COc1ccc2c(c1)C(=O)CC(c1cccc(OC)c1OC)O2 +CCn1nc(C)cc1NC(=O)c1ccc(F)c(F)c1 +NC(=O)CC1CCN(C(=O)c2cccc(-c3ccoc3)c2)CC1 +CCOC(=O)c1[nH]c(C)c(C(=O)OCc2nc3ccccc3o2)c1C +COC(=O)c1cnc(NC(=O)COc2ccc(C)cc2C)s1 +Cn1ncc(C(=O)Nc2cc(CC3CCCCC3)n[nH]2)c1C(F)F +Cc1cc(N2CCN(Cc3cccnc3C)CC2)nc(C)n1 +CCCCNC(=O)C(C)Oc1cccc(OC)c1 +Nc1c(NCc2ccccc2)ncnc1-n1nnc2ccccc21 +COC(=O)CCCN1C(=O)C(C)Nc2cc(OC)ccc21 +COCCOc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)cc1 +COc1ccc(C(C)=O)cc1CC(=O)NCC1(C)CC1 +Cc1cccc(-n2nc(C#N)cc2-c2ccccn2)c1 +CS(=O)(=O)c1cccc(OCCCOc2cccc(Cl)c2)c1 +COc1ccc(-n2nnc(-c3cccs3)c2N)cc1 +CCNS(=O)(=O)c1c(C)sc(C)c1-c1cc(C)no1 +O=C(COC(=O)c1c(F)cccc1F)NCCC1=CCCCC1 +CN(CC(F)(F)F)C(=O)c1cc(C2CC2)n(C(C)(C)C)n1 +CCCNC(=O)c1ccc(NC(=O)N2CCc3ccccc3C2)cc1 +COC(=O)c1sc2nc(-c3cnn(C)c3)[nH]c(=O)c2c1C +COCCNC(=O)CCc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +CC(NC(=O)c1ccc2nnnn2c1)c1nc2ccccc2[nH]1 +Nc1ccc(Cl)c(NC(=O)c2cc3ccccc3oc2=O)c1 +COc1cccc2cc(C(=O)NCc3ccsc3)c(=O)oc12 +CC(C)Oc1cncc(C(=O)OC(C#N)C2CC2)c1 +CCn1nc(Cn2cncn2)nc1CSc1nnc(C)s1 +O=C(NCc1ccncc1)C1CC(=O)N(CCc2ccc(F)cc2)C1 +Cc1cc(C)nc(NC(=O)NCC(O)c2ccccc2F)c1 +CC(CNS(=O)(=O)c1ccc(N)cc1)c1ccc(F)c(F)c1 +Cc1nc2ccc(Br)cn2c1CC(=O)N(C)C +CCn1cnnc1-c1cccc(NC(=O)C(C)c2cccs2)c1 +CCCn1c(N)c(NC(=O)c2ccsc2)c(=O)n(CCC)c1=O +COc1ccc(NC(=O)N2CCC3(CC2)OCCO3)cc1OC +COc1cccc2c1N(C(=O)Cc1cn3ccsc3n1)CCC2 +O=C(c1ccccn1)N1CC2CCC(C1)N(Cc1ccccn1)C2=O +COc1ccc(OC)c(S(=O)(=O)N(C)CCC#N)c1 +Cc1ccc(C(C)NS(=O)(=O)c2ccc(C#N)c(Cl)c2)o1 +O=C(Nc1nc2c(s1)CN(C(=O)c1cccs1)CC2)C1CCC1 +CCCNC(=O)c1cn(Cc2ccccc2)nc1-c1cccs1 +CC1CN(C)c2ccccc2N(C(=O)c2cc(C(N)=O)cs2)C1 +O=C(Cn1nc2ccccn2c1=O)Nc1ccc2ccccc2c1 +Cc1ccc(S(=O)(=O)N(CC(C)O)c2ccccc2)cc1C +Cc1ccc(C(=O)NCc2cc(=O)oc3cc(C)ccc23)cc1 +CN(Cc1cccnc1)C(=O)CCOCC1CCCO1 +O=C(COc1ccc2c(c1)OCO2)Nc1ccc(F)cc1 +COC(=O)CN(C)C(=O)c1coc(COc2ccccc2)n1 +COc1ccc(CCC(=O)Nc2c(F)cccc2F)cc1OC +COCCCNC(=O)c1cc2ccccc2oc1=O +CCN(Cc1ccccc1NCc1ncc(C(C)(C)C)o1)C(C)=O +O=c1[nH]c(N2CCCC2)nc2ncc3c(c12)-c1ccccc1C3 +O=C(Cc1cccc(Cl)c1)NCCCN1CCCCCC1=O +CCn1nc(C)c(CN2CCOC(c3ccccc3F)C2)c1C +Cc1ccc(C)c(Oc2cc(-n3ncc(C#N)c3N)ncn2)c1 +O=C(Cc1noc2ccccc12)NCc1ccccc1F +COCC(C)NC(=O)NCc1cc(F)ccc1F +Nc1ncnc2c1nc(C(F)(F)F)n2C1OC(CO)C(O)C1O +CS(=O)(=O)N(CC(=O)Nc1ccccc1)c1ccc(F)c(F)c1 +CC(=O)Nc1ccccc1-c1nc2cccnc2[nH]c1=O +COc1cc2c(cc1OC)NC(=O)C(CCC#N)C2 +CC(C)C(CNC(=O)Cn1cccn1)N1CCOCC1 +COc1cc(C)ccc1OCCC(=O)NC(C)c1c(C)noc1C +c1ccc2c(c1)oc1c(NCCNc3cnccn3)ncnc12 +O=C(CSc1ccncc1)N1CCCC(c2ccccc2)C1 +CCn1cc(C(=O)Nc2nc(C)cs2)c(=O)c2ccc(C)nc21 +CC(Sc1nnc(NC2CC2)s1)C(=O)Nc1ccccc1 +Cc1c(-c2noc(C3CCCC3)n2)nnn1-c1ccc(F)cc1 +Cc1ccc(N2CCC(C(=O)NC3CC3)C2=O)cc1Cl +O=C(NCC(O)c1ccc(C(F)(F)F)cc1)C1CCCCC1 +Cc1cc(S(=O)(=O)N(C)CCOCC2CC2)ccc1F +COC(=O)C1=C(C)NC(=O)CC1c1ccccc1Cl +CCC(C)Cn1nc(-c2ccc(F)cc2)oc1=O +Cc1ccc(CNC(=O)Nc2ccc3c(c2)OCC(=O)N3)c(C)c1 +O=C(CCc1nc(-c2ccc(Cl)cc2)no1)NCc1cscn1 +CC(=O)c1ccc(NC(=O)N(C)CC(=O)Nc2ccccc2)cc1C +c1ccc2c(c1)CC(NCc1cccn1-c1nccs1)CO2 +c1ccc2c(c1)CC(CNc1ccc3nnnn3n1)CO2 +CC(=O)NCCNC(=O)C1CC(=O)N(c2cccc(Cl)c2)C1 +CCOC(=O)c1ccsc1NC(=O)c1c(F)cccc1Cl +Brc1cnc(Sc2nnnn2CC2CCCO2)nc1 +CC(=O)Nc1cccc(-c2cnc3ccccc3n2)c1 +Cc1ccc2c(c1C)OCCC2NCCCN1CCOCC1 +CN1CC(n2cnc3c(F)cccc3c2=O)CC1=O +O=C(CCS(=O)(=O)c1ccccc1)NC1CC(=O)N(C2CC2)C1 +CC=CCOC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1sc(NC(=O)c2cccnc2)nc1-c1ccc(F)cc1 +NC(=O)COCCNC(=O)C1CC1c1ccc(Br)cc1 +C=CCNS(=O)(=O)c1ccc(C(=O)CC)cc1 +CC(=O)c1cccc(NCC(O)c2ccc(F)c(F)c2)c1 +O=C(NC1CCCC1)C1CCN(C(=O)NC2CC2)CC1 +COC(=O)Cc1cc(=O)oc2cc(O)cc(O)c12 +N#Cc1cc(C2NCCc3ccccc32)ccc1F +CN(C)C(=O)c1ccc(Oc2ccc(C(=O)N(C)C)cc2)cc1 +C=C1CSc2nc(=O)c3c(C)c(C)sc3n21 +COC(=O)c1c(C)[nH]c(C(=O)N2CCCC(O)C2)c1C +COc1ccc(Cl)cc1CNc1ccc(C#N)cn1 +NC(=O)c1ccc(CNCCc2ccccc2)cc1 +CC(C)n1nccc1NC(=O)NCCCn1nc2n(c1=O)CCCC2 +NS(=O)(=O)Cc1ccc(CNC(=O)N2CCOCC2)cc1 +CCCn1nccc1NC(=O)c1cnc(Cc2ccccc2)s1 +CC(C)C(NC(=O)NCCO)c1ccc(Cl)cc1F +CCCCN(CCCC)C1(O)C(=O)Nc2ccccc21 +Cc1cnc(C(=O)Nc2n[nH]c(-c3ccc(F)cc3)n2)cn1 +COc1cccc(OC(C)C(=O)Nc2nc(C)c(C)s2)c1 +CC(C)c1nnc(NC(=O)c2ccc[nH]c2=O)s1 +Nc1nc2c(nc(N)n2Cc2ccccc2)c(=O)[nH]1 +CN(C)C(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +O=S(=O)(c1cc(Cl)ccc1Cl)N1CCCCC1CO +O=C(NCCO)Nc1ccc(OCC(F)(F)F)c(C(F)(F)F)c1 +COCC(NC(C)c1cnc(C)s1)c1cccc(C(F)(F)F)c1 +CCc1nnc2n1CCN(C(=O)c1cc(-c3ccc(C)cc3)no1)C2 +O=C(Nc1nnc(C2CC2)s1)c1cc(Br)ccc1F +O=C(CSc1nc(-c2ccco2)n[nH]1)c1ccc(O)cc1O +COC(=O)C1CCN(C(C)c2nc(=O)c3ccccc3[nH]2)CC1 +CCc1ccc(Cl)c(CC)c1NC(=O)c1ccc(NC(C)=O)cc1 +COCc1cc(CNC(=O)Cc2ccc[nH]2)ccc1F +C=CCCCN(C)C(=O)NC1CCN(c2cnn(C)c2)C1=O +CCS(=O)(=O)NCCc1c[nH]c2ccccc12 +O=C(CSc1ccccn1)N1CCn2c1nc1ccccc12 +Cc1cc(NC(=O)CCn2cc(C)cn2)c2ncccc2c1 +Cn1cnc(N)c1S(=O)(=O)Nc1ccccc1 +CCN(CC)C(=O)c1cc(Br)c2c(c1)OCCO2 +COc1ccc2c(c1)CCCN2C(=O)COc1ccccc1CO +O=C(CNC(=O)c1cc(-c2ccc(F)cc2)[nH]n1)NCc1ccco1 +Cc1nc(SCc2cccc(C(=O)N(C)C)c2)n(C2CC2)c1C +CC(=O)NCc1ccc(C(=O)OC(C)C(=O)c2ccc(F)cc2)cc1 +COc1ccc(CNc2ccccc2-n2ccc(C)n2)cc1OC +Cc1cccc(NC(=O)CCc2nc3ccccc3[nH]c2=O)n1 +CCn1cc(Cl)c(C(=O)N2CCCC(C)C2)n1 +CCC(C#N)S(=O)(=O)N(C)Cc1sccc1Br +CS(=O)(=O)N1CCCC1C(=O)NCc1ccccc1Cl +Cc1cc(C)c(NC(=O)Cc2nc3nc(C)cc(C)n3n2)c(C)n1 +COC(=O)CSc1nc2sc3c(c2c(=O)n1C(C)C)CCC3 +CCC(C)c1ccc(C(=O)Cn2cc(N)cn2)cc1 +CCCCCC(NC(=O)c1nccnc1N)c1ccccc1 +O=C(NC1CCCCC1)c1ncoc1-c1ccco1 +CCn1c(C)cc(C(=O)NCc2ccc(C)cc2)c1C +CCN1CC(C(=O)N2CC(C)OCC2C)CC1=O +CN(C)c1nc(N)nc(COC(=O)c2ccc3c(c2)CCC(=O)N3)n1 +CC(=O)Nc1cc(C(=O)NC2CC2)ccc1Sc1ccc(F)cc1 +Cc1cc(NC(=O)CCOCc2ccccc2)ccc1C(=O)N(C)C +COCCn1cc(NC(=O)CSc2ccncc2)cn1 +COc1ccc(C)cc1C(O)CN(C)Cc1ccccc1 +O=c1[nH]c(NCCc2cccs2)nc2ccccc12 +NC(C(=O)NCCc1ccc2c(c1)OCO2)c1ccccc1 +CCOC(=O)c1cc(-c2cccc(N)c2)nn1CCO +CCCNC(=O)c1cccc(C(=O)Nc2cccc(C)n2)c1 +CC(C)n1cnnc1SCC(=O)N(C)C1=CCCC1 +COc1cc(C(=O)N(C)C(C)C)ccc1OC1CCCC1 +Cc1cc(NC(=O)CCn2cc(CO)nn2)no1 +COc1cccc(OCCNC(=O)N(C)Cc2ccoc2C)c1 +O=C1NC2C(CO)CC=CC2c2cc3c(cc21)OCO3 +O=C(NCc1ccc(-n2ccnc2)nc1)N1CCc2sccc2C1 +CC(C)OC(=O)CCNC(=O)NCc1cccc(Cl)c1 +O=C(Nc1ccc(CN2CCOCC2)cn1)c1cncc(F)c1 +Cn1ccnc1C(=O)c1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +Cc1ccc(NC(=O)Nc2nnc(N3CCCC3)s2)cc1 +Cc1oc2ncnc(NC(=O)c3ncn(-c4ccccc4)n3)c2c1C +CC(C)C(=O)Nc1cnc(-c2ccc(Cl)cc2)nc1 +O=c1[nH]ncc(N2CCN(CCO)CC2)c1Cl +COc1cccc(NC(=O)CSc2nc(=O)n3ccccc3n2)c1 +Cc1cc2c(cc1F)CCNC2c1[nH]c(=O)[nH]c(=O)c1F +Cc1cccc(NC(=O)c2cc(C3CC3)nn2-c2ccccc2)n1 +COC(=O)c1cc(S(=O)(=O)N(C)CC(=O)NC2CC2)cn1C +COc1ccc2c(=O)c(C(=O)NCCNC(C)=O)c[nH]c2c1 +CCCC(=O)OCc1cc(Cl)c2c(c1)OCO2 +CCCc1nc2cc(F)c(F)cc2n1CC(C)C#N +CC(NC(=O)c1ccnc(N(C)C)c1)c1nnc2n1CCC2 +CC(=O)Nc1ccc(CNc2cccc(C)c2N)cc1 +O=C(Nc1ccccc1-n1cnnn1)c1cc2cc(Cl)ccc2o1 +Cc1nc(N(C)C)ncc1C(=O)Nc1ccc2c(c1)OCO2 +CN(CCC(F)(F)F)C(=O)Cc1ccc(OC(F)F)cc1 +Cc1nsc(N2CCN(Cc3ccc(C#N)o3)CC2)n1 +CCOc1cccc(NC(=O)c2c(C)cc(C)[nH]c2=O)n1 +CC(c1ccccc1Cl)N(C(=O)c1ccsc1)C1CC1 +N#Cc1ccc(OCC(=O)N2CCCC2c2nnc3ccccn23)cc1 +CN(CCc1ccccn1)c1ccc(S(=O)(=O)C(C)(C)C)nc1 +COc1ccc(C(=O)C2CCCN(C(=O)c3cc[nH]n3)C2)cc1 +Cc1ccc(C)c(NC(=O)C(c2ccccc2)n2cnnn2)c1 +COc1cccc(C(=O)Nc2nc(C(C)C)n[nH]2)c1F +Cc1ccc(C(C)(NCC(F)(F)F)C(N)=O)cc1 +Cc1occc1-c1nnc(SCC(=O)c2cc(F)ccc2F)n1C +CC(NC(=O)CCC(=O)NCc1ccc(F)cc1)c1ccccc1 +OCc1nnn(Cc2cccc(F)c2)c1-c1ccccc1Cl +CC(C)c1nnc2sc(C3CC(=O)N(Cc4ccncc4)C3)nn12 +CC(C)c1nnc(CNc2ncc(F)cn2)n1C +CC(C)(C)OC(=O)N1CCC(Br)(Br)CC1 +CC(=O)NCC(c1ccco1)N1CCN(c2ccc(F)cc2)CC1 +Cc1sc(CCN2CCCC2=O)nc1-c1ccc(F)cc1F +CCn1cc(C(=O)Nc2ccc(-c3nc(C)cs3)cc2)cn1 +CCOc1ccc(CC(=O)Nc2sccc2C(N)=O)cc1 +COc1ccc(Nc2nc(C)cc(=O)[nH]2)cc1OC +COc1ccc(NC(=O)n2ncc3ccccc32)cc1OC +COCc1ncc(C(=O)N2C(C)CCCC2C)c(N)n1 +Cn1c2ccccc2n2c(=O)n(CC(=O)NC(C)(C)C)nc12 +COc1cc(CN(C)Cc2nnnn2C)ccc1SC +CN(Cc1ccncc1)C(=O)Nc1cccc(S(N)(=O)=O)c1 +O=S(=O)(c1cccc(-c2cc(O)cc(F)c2)c1)N1CCCC1 +COc1ccccc1C(=O)Nc1ccc(O)cc1C +Cc1noc(C)c1S(=O)(=O)NCc1cccc(NC(=O)C2CC2)c1 +Cc1ccc(-n2nnc(C(=O)Nc3nc(C)no3)c2C)cc1 +Cc1cnc(C(=O)Nc2cccc(-c3nc[nH]n3)c2)cn1 +C#CCOC(=O)CCCN1C(=O)c2ccccc2N2C(=O)CCC12C +Cc1ccc(-c2nc(N)n(C(=O)c3ccccc3F)n2)cc1 +Cc1cc(C(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)no1 +CCn1cc(NC(=O)c2sccc2NC(=O)c2ccoc2)cn1 +O=C(COCC(F)(F)F)N1CCC(OCc2ccccc2F)CC1 +Cc1nc(-c2ccccc2)sc1C(C)NC(=O)C1CCCO1 +COc1ncccc1CNC(=O)c1cn(C)nc1C(C)(C)C +Cc1cc(CNC(=O)c2ccc(NC(=O)C3CC3)cc2)ccc1F +c1csc(-c2noc(CSc3nnc(Cn4cncn4)o3)n2)c1 +CS(=O)(=O)NCCSc1ncnc2c1cnn2-c1ccccc1 +CSc1nnc(CNC(=O)Nc2cccc(C(C)=O)c2)n1C +CCC(CC)N(C)C(=O)CCOc1ccccc1N +CCCC1C(C(=O)OC)=C(C)N=C(C)C1C(=O)OC +O=C(NCCn1ccnc1-c1ncccn1)NCc1cccs1 +Cc1ccc(C(=O)Nc2nnc(Cc3nc4ccccc4[nH]3)s2)cc1 +O=C(Nc1cccnc1)C1CCCN1S(=O)(=O)c1cccs1 +O=C(CCNc1ncccn1)N1CCN(c2ccc(F)cc2)CC1 +O=C1CCN(C(=O)c2cc(Cl)c3c(c2)OCCO3)CCN1 +COc1ccccc1C(=O)NCCC(=O)OC(C)C +CC(C)CNC(=O)CNC(=O)c1cnn2c1OCCC2 +COc1cc(C(=O)NC2c3ccccc3CC2C)cc(OC)c1OC +CC(C#N)Sc1nc2ccsc2c(=O)n1Cc1ccccc1 +Nc1cc(F)c(F)cc1NC(=O)Cc1cccs1 +CN1c2ccccc2C(=O)NC1c1csc(C2CC2)n1 +CC(NC(=O)CCCNC(=O)C(C)(C)C)c1ccncc1 +CC(CN1CCOCC1)NC(=O)c1n[nH]cc1N +CC(C)(C)c1ccc(Cn2nccc2NC(=O)c2cnccn2)cc1 +CCC(CNC(=O)NCc1noc(C)n1)Oc1cccc(F)c1 +Cc1c(C)c(C)c(S(=O)(=O)NCCc2ccncc2)c(C)c1C +CCc1nnsc1C(=O)N1CCCC(n2nc(C)cc2C)C1 +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)Nc1c(C)n[nH]c1C +Cc1ccc(CNC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)o1 +C#CCNC(=O)NC(CC)c1ccc(Cl)cc1 +CCCS(=O)(=O)Nc1ccc(N2CCCC2=O)c(C)c1 +Cc1cc(C(=O)CN2CCN(c3cnccn3)CC2)c(C)n1C(C)C +CCC1C(=O)NCCN1C(=O)CCOC(C)CC(C)C +CNC(=O)Cc1ccc(NCC(=O)Nc2cc(C)on2)cc1 +O=C(Cc1c(F)cccc1F)NCCOc1ccc(F)c(F)c1 +COc1ccc(-c2nn(CCC#N)cc2C(=O)OC(C)C)cc1 +Cc1ccc(C(=O)NCCc2csc(C)n2)c(C)n1 +O=C(Nc1cccc2ncccc12)c1coc(NC(=O)c2ccco2)n1 +CN(CCC(F)(F)F)C(=O)Cn1ncc(=O)c2ccccc21 +Cc1cccc(-c2nc3c4cnn(C)c4ncn3n2)c1 +CC(CC#N)Sc1ccccc1NC(=O)NCc1cccs1 +Cc1cc(Br)ccc1C(=O)N1CCN(CC(C)O)CC1 +NC(=O)CC1CCN(C(=O)NCCOc2ccccc2)CC1 +COc1ccc(C(=O)COC(=O)c2cccc(S(C)(=O)=O)c2)cc1 +CC(NC(=O)NC1C=CC(CO)C1)c1csc2ccccc12 +Cc1ccc(S(=O)(=O)NCCNS(C)(=O)=O)c(C)c1 +Cc1cc(NC(=O)CCc2c[nH]c3ccccc23)ccc1-n1cnnn1 +Cc1cc(C)n(C2CCN(c3cc(C(C)C)nc4ccnn34)C2)n1 +Cn1nc(N2CCN(C(=O)c3cccs3)CC2)c(=O)n(C)c1=O +C=CCNC(=O)c1cc2cnn(C(C)CC)c2nc1N +CC1CN(CCCC(N)=O)c2ccc(Cl)cc2N1 +CS(=O)(=O)Oc1cccc(CN(C(=O)c2ccco2)C2CC2)c1 +CCc1ccc(C(COC)NC(=O)c2cc(C3CC3)on2)o1 +c1ccc(Cc2n[nH]c(CCc3cccnc3)n2)cc1 +COc1ccc(CNC(=O)C(C)c2cccs2)cc1 +CC(C)c1noc(CCCC(=O)Oc2ccc(C#N)cc2Cl)n1 +N#Cc1nccnc1Sc1nc(C2CC2)n(-c2ccccc2)n1 +CC(=O)N1CCN(C(=O)c2cc(-n3cccc3)ccc2Cl)CC1 +CC(C)C(Sc1ccccn1)C(=O)N1CCc2ccccc2C1 +CCc1nnnn1-c1ccccc1NC(=O)c1cc(C(C)C)on1 +CCC(CC1CCCCC1)C(=O)N1CCN(S(=O)(=O)CC)CC1 +Cc1cc(C(=O)Cn2ccccc2=O)c(C)n1CC(F)(F)F +CN(C)c1nnc(-c2ccc(NC(=O)c3ccc(=O)n(C)c3)cc2)o1 +COCCNC(=O)c1cnc(-c2ccc(C(F)(F)F)cc2)nc1C +CCOc1cccc2cc(C(=O)n3ccc(C)n3)c(=O)oc12 +CCc1nnc(SCC(=O)Nc2cccc(Cl)c2C)n1C +Cc1ccc(-c2c(C)noc2C)cc1S(=O)(=O)N1CCCC1 +N#CCOc1cccc(CC(=O)NC2CCC(CO)CC2)c1 +CCCOc1ccccc1NC(=O)NCc1cccc(C(N)=O)c1 +Cc1ccc(SCc2nc(N)nc(N)n2)c(C)c1 +CC1CCCCC1NC(=O)C(C)S(=O)(=O)c1ncccc1Cl +CC(=O)N1CCC(C(=O)OCC23CC4CC(CC(C4)C2)C3)CC1 +COc1cc(C#N)ccc1OC(=O)c1ccccn1 +O=C(NCc1ccc(Cl)cc1)Nc1cnn(CC(F)(F)F)c1 +COC(=O)c1ccc(C(=O)NCCCS(N)(=O)=O)cc1 +CCC(OC)C(=O)Nc1ccc(-n2cncn2)c(F)c1 +CCN(CC)S(=O)(=O)c1cc(N)ccc1Cl +Cc1oc2ncn(CC(=O)NCC(C)c3ccccc3)c(=O)c2c1C +Cc1nc(C)n(Cc2cn3ccccc3c2C#N)n1 +Cc1cnn(C(=O)c2nn(C)c(C)c2Br)c1 +O=C(NCc1nc(-c2ncccn2)no1)C1(c2ccc(F)cc2)CC1 +CC(=O)N1CCCC(C(=O)N2CCN(c3ccc(C#N)cn3)CC2)C1 +COc1ccccc1-c1ccc(=O)n(CC(=O)OC(C)C)n1 +CN(CCC(F)(F)F)S(=O)(=O)c1ccccc1C(F)(F)F +CCOC(=O)c1cnn(Cc2nc(-c3ccccn3)no2)c1N +COc1cc(OC)c2c(=O)c(-c3ccc(O)cc3)coc2c1 +Cc1nn(C)c2c(NCCCn3cccn3)ncnc12 +NC(=O)COc1ccc(C(=O)NCc2ccccc2)cc1N +NC(=O)C1CCCN1C(=O)NCCCN1CCCC1=O +O=C(CN1CCc2sccc2C1)Nc1cccnc1 +Cc1ncc(CN2C(=O)C(=O)c3ccc(Br)cc32)s1 +CCNC(=O)CNc1cccc(C(=O)N2CCC(C)CC2)c1 +COC(=O)COc1cccc(NC(=O)c2ccccc2F)c1 +CS(=O)(=O)c1ccc(C(=O)NC(Cc2ccccc2)C2CC2)cc1 +CC(=O)N1CCC(C(=O)OCC(=O)N2CCCCCC2)CC1 +Cc1cc(OCCc2cccc(F)c2)nc(C)c1N +CCCC(C)N(C)S(=O)(=O)c1ccc(N)cc1Br +O=C(NC1CCc2ccccc21)N1CCOCC1C1CC1 +CC(OCC1CCCCN1C(=O)OC(C)(C)C)c1ccc[nH]1 +O=S(=O)(NC1CC1)c1ccc2c(c1)OCCCO2 +Cc1cc(C(=O)NCc2ccc(-n3ccnc3)cc2)nn1C +Cc1n[nH]cc1NC(=O)c1ccc2ncsc2c1 +COC(=O)c1cc(NC(=O)Cc2cccc(F)c2)c[nH]1 +CCOc1cc(C2NC(=O)c3[nH]nc(-c4ccco4)c32)ccc1O +O=C(NCc1ccnc(OC2CCC2)c1)Nc1ccc(F)cc1F +CC1CCCCN1C(=O)c1cc(Cl)c2c(c1)OCCO2 +CCn1cnc2cc(-c3noc(CNC(=O)c4ccccc4)n3)ccc21 +O=C(CSc1ncccn1)Nc1ccc2c(c1)OC1(CCCC1)O2 +CC(C)CCSc1nnc(C2CCCN2C(=O)OC(C)(C)C)o1 +COc1cccc(-c2noc3ncnc(NCc4cccnc4)c23)c1 +COc1ccc2c(c1C)C(c1ccccc1C#N)NCC2 +CNC(=O)c1ccc(CNC(=O)c2cc(C)c(C)[nH]c2=O)o1 +Cc1occc1C(=O)N1CCCC(c2nc3ccccc3o2)C1 +C#Cc1cccc(N(C)C(=O)c2[nH]ncc2Br)c1 +CCc1ccc(CC(=O)NCC(O)c2ccco2)cc1 +CC(=O)c1csc(NC(=O)C2(c3cccc(F)c3)CCOCC2)n1 +Cc1cccc2nc(-c3ccc(F)c(F)c3F)nn12 +O=C(Cc1ccc[nH]1)NCCc1nc2ccccc2[nH]1 +NC(=O)COC(=O)C1(c2ccc(F)cc2)CCOCC1 +Cn1cc(C(=O)Nc2ccc(C(N)=O)nc2)c(-c2cccs2)n1 +CC(C)(C)c1ccc(NC(=O)CSc2n[nH]c(=O)n2C2CC2)cc1 +Cc1n[nH]c(C)c1C(=O)Nc1nc2c(s1)CCC2 +CC1(C)COCCN1C(=O)c1cccc(NC(N)=O)c1 +CCOC(=O)c1c(C)oc2ccc(OCC(N)=O)cc12 +O=C(NCc1ccc(OCc2ccccn2)cc1)N1CCCC1 +COc1ccc(Cl)c(NC(=O)N(C)CCN2CCOCC2)c1 +Cc1ccc(NC(=O)c2cn(C)c3c(Cl)cccc3c2=O)c(C)c1 +CCC1COC(C)CN1C1CC(C(C)C)CCC1N +COCc1cc(C(=O)NCC(C)c2nc(-c3ccccc3)no2)no1 +Cc1ccc(NC(=O)c2cc(C)nc3c2cnn3C(C)C)cc1 +CCn1c(C)nnc1S(=O)(=O)CCc1ccc(C)cc1 +COC(=O)CC1C(=O)NCCN1Cc1ncc(C(C)(C)C)o1 +CC(=O)c1cccc(NC(=O)c2cnn(-c3ccncc3)c2C)c1 +CC1CCCN(S(=O)(=O)NCC(O)c2ccccc2Cl)C1 +Cc1cc(C)n2ncc(CN(C)Cc3nc(-c4ccncc4)no3)c2n1 +CC(C)C(c1cccnc1)N(C)C(=O)C#Cc1ccc2c(c1)OCO2 +Cc1ccc(S(=O)(=O)Nc2cc(S(N)(=O)=O)ccc2C)cc1 +CCC(C)C(NC(=O)c1n[nH]c2ccccc12)C(N)=O +Cc1ccc(C(=O)CCSc2nnc(-c3ccncc3)o2)cc1 +COc1ccc(-c2ccc(N)cc2Cl)cc1OC +Cc1sc(=O)n(CCC(=O)NC(C)(C)c2cccc(F)c2)c1C +CC(C)CCC(C)NC(=O)Cn1c(=O)oc2ccccc21 +CC(=O)N1CCC(NS(=O)(=O)Cc2ccc(F)cc2)CC1 +O=C(CCn1ncc(=O)c2ccccc21)OCc1cccc(F)c1 +CC(Sc1ccccc1)C(=O)N1CCN(C(=O)C2CCCO2)CC1 +CC1CN(Cc2cnc3ncccn23)C(c2ccccc2)CO1 +O=C(Cn1cnc(S(=O)(=O)N2CCCC2)c1)N1CCCCCC1 +N#Cc1ccc(NC(=O)NCCCN2CCOCC2)cc1 +COC(=O)c1cc(C)nc(Nc2ccccc2OC)n1 +COc1ccc(F)cc1NC(=O)c1cccc(OC)c1F +Cc1cc(C(C)(C)C)cc(C)c1CC(=O)NCCO +Cc1ccc(F)cc1S(=O)(=O)NCc1cn(-c2ccccc2)nn1 +Cc1nn(-c2ccccc2)c(C)c1CN1CCCC(c2cn[nH]c2)C1 +Cc1cccc(C(=O)Nc2cccc(C(=O)N(C)C)c2)n1 +Cc1ccc(C(=O)NCCNC(=O)c2ccccn2)cc1 +CC(NS(=O)(=O)c1cccs1)c1ccc2c(c1)NC(=O)CO2 +O=C(CN1C(=O)COc2ccc(CO)cc21)N1CCCC1 +O=C1NCC2(CCCN(C(=O)c3ccccc3N3CCOCC3)C2)O1 +COC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2ccccc2Cl)c1C +CC(C)(C)c1ccc(S(=O)(=O)NC2C=CC(CO)C2)cc1 +O=C(NCc1cccnc1)C1(c2ccccc2)CCOCC1 +Cn1nc(C(=O)N2CCn3nc(Cc4ccccc4)cc3C2)ccc1=O +O=S(=O)(NCC1COC2(CCCCC2)O1)c1ccc(Cl)cc1 +Cc1sc(=O)n(CC(=O)N(C)CCCOc2ccccc2)c1C +COc1ccc(CC(=O)Oc2ccc(C#N)cc2)cc1F +COc1ccc(C(C)NC(=O)NCc2cccs2)cc1F +N#Cc1cccn1-c1ccc(OC(F)(F)F)cc1 +CCC(=O)N1CCN(c2ccccc2NC(=O)c2ccccc2)CC1 +CCc1nnnn1-c1ccc(Br)cc1 +CC1Oc2ccc(S(=O)(=O)NCC3CCCO3)cc2NC1=O +C#CCN1CCN(C(=O)NCCCOc2cccc(OC)c2)CC1 +Cc1cccc(C2(Cc3ccco3)NC(N)=NC2=O)c1 +NC(=O)c1sc2nc(-c3cccs3)c3c(c2c1N)CCCC3 +Cc1ccnc(NC(=O)c2cc(C(F)(F)F)n[nH]2)c1 +O=C(C1COc2ccccc2C1)N1CCCC1c1noc(C2CC2)n1 +COc1ccc2nc(-n3nc(C)cc3NC(=O)C(C)C)sc2c1 +CC(=O)N1CCCc2cc(S(=O)(=O)CC#N)ccc21 +CS(=O)(=O)NCCC(=O)N1CCc2sccc2C1 +CC(C)(C)OC(=O)NCC(=O)N1CCN(c2cc(C#N)ccn2)CC1 +COc1cc(CNC(=O)Nc2ccc(F)cc2)ccn1 +CCC1(CNC(=O)Cc2ccc(F)c(F)c2)CC1 +CCN(CCc1nc2ccccc2c(=O)[nH]1)Cc1cccs1 +Cc1nonc1NC(=O)Cc1cccc(OCC#N)c1 +Cc1ccc(NC(=O)C2CN(C(=O)c3ccc(F)c(F)c3)C2)c(C)c1 +COc1cc(-c2nnc3n2C(=O)CS3)cc(OC)c1OC +Cc1csc(SCC(=O)Nc2ccccc2C(=O)NC2CC2)n1 +Cc1cnn(CC2CN(Cc3cccnc3)CCO2)c1 +CC(=O)Nc1ccc(C(=O)N2CCC(CO)CC2)s1 +COc1ccc(SC(C)C(=O)N2CCCC(C)C2)cc1 +O=C(NCCC(=O)N1CCCCC1)c1cccn1Cc1ccccc1 +O=c1c2ccccc2nc(SCC2(CO)COC2)n1C1CCCC1 +CC(NC(=O)c1cc(N)ccc1Cl)C1CCCO1 +CCCC(=O)Nc1ccc(C)n(CC(=O)NCC2CCCCC2)c1=O +CCCC(=O)NC1CCN(c2nccs2)CC1 +O=C(Nc1ccc(NC(=O)C2CC2)cn1)c1ccco1 +O=C(c1cc(-c2cccnc2)on1)N1CCN(c2cnccn2)CC1 +Cc1nnc(SC(C)C(=O)NC(C)c2ccc(Cl)cc2)s1 +Cc1nc(-c2cc(C(=O)NC3CCCCC3)n(C)c2)cs1 +CCOC(=O)c1cn2ccccc2c1S(=O)(=O)c1ccccc1 +O=C(CCc1ccsc1)Nc1cccc(CN2CCOC2=O)c1 +Cc1ccc(F)c(NC(=O)NCCC(=O)N2CCCC2)c1 +CCOC(=O)C1=C(C)NC(=O)NC1c1ccc(OC(F)F)cc1 +Cc1cc(C)nc(NCCC(=O)Nc2cccc3c2ccn3C)n1 +Cc1ccc(OC(C)C(=O)NCc2ccccc2F)cc1 +COC(=O)c1cccc(-n2nnnc2-c2ccc(C)c(N)c2)c1 +Cc1ccc(C)c(CNc2ccc(C(=O)N3CCOCC3)cc2)c1 +CCC(=O)Nc1ccc(NC(=O)COc2ccc(C)cc2)cc1 +Cn1cc(S(=O)(=O)NC2CCCCC2C(C)(C)C)cn1 +CC(C)Oc1cc(CNC(=O)c2ccc(-n3ccnn3)cc2)ccn1 +Cc1ccccc1-c1ncc(C(=O)N2CCOCC2)c(N)n1 +Cc1cc(Br)cc(C)c1NC(=O)CCC1CCCO1 +COC(=O)c1c(NC(=O)c2ccno2)sc2c1CCN(C(C)=O)C2 +COc1ccc(C(=O)Nc2ccccc2CO)cc1OC +Cc1csc(C(=O)Oc2ccc3c(c2)ncn3C)c1 +NS(=O)(=O)c1ccc(NC(=O)c2cc3ccccc3o2)cc1 +NC(=O)c1ccc(NCc2cc(=O)n3ccccc3n2)cc1Cl +Cc1cnn(CC(=O)NCc2c(C)cc(C)[nH]c2=O)c1 +NC(=O)c1cnc(N2CCC(NC(=O)c3ccoc3)CC2)c(Cl)c1 +Cc1ccc2[nH]nc(C(=O)NCc3cc4ccccc4o3)c2c1 +O=C(NC1CC1)c1ccc(NC(=O)c2cccc3ncccc23)cc1 +Cc1cc(S(=O)(=O)Nc2[nH]nc(C)c2C)c(C)o1 +Cc1cc(NC(=O)NCCCOCC2CCOCC2)ccc1F +Cc1cccc(C(=O)N2CCCC(C(=O)Nc3ccc(F)cc3)C2)c1 +NC(=O)C1CCN(C(=O)c2n[nH]c3ccccc23)CC1 +Cc1ccc2c(CC(=O)NCc3cc(C)oc3C)coc2c1 +CCOC(=O)c1nc2sc(Cc3cccs3)nn2c1C#N +NC(=O)c1cccc(CNS(=O)(=O)c2cccs2)c1 +CCOc1ccc(C2=CCN(C(=O)CNC(=O)CC)CC2)cc1 +COCCNC(=O)C1CCN(C(=O)c2cc3sccc3n2C)CC1 +O=C(Nc1cccc(Cl)c1Cl)N1CCC2(CC1)OCCO2 +COC(=O)C1(CNc2ccc3nnc(C(F)F)n3n2)CCCCC1 +Cc1ccc(C2CC(C)CCN2C(=O)NCc2ncn(C)n2)o1 +CC(=O)c1csc(NC(=O)CCSc2nnnn2C)n1 +CC(NC(=O)c1cncc(Br)c1)C1CC1 +O=C(CCC(=O)c1ccc(F)cc1F)NCc1cccs1 +O=C(Cc1c(F)cccc1Cl)N1CCN(Cc2ccco2)CC1 +CSc1ccc(OCC(=O)Nc2cc(C)nn2C)cc1 +Cc1c(C(=O)Nc2ccc3c(c2)OCCO3)[nH]c2c1C(=O)CCC2 +O=C(c1ccccc1)N1CCCC2(CC(Oc3cccnc3)CO2)C1 +CC(c1nc2ccccc2s1)N(C)C(=O)c1ccc(F)cc1 +O=C(NCCc1csc(-n2cccn2)n1)C1CC1 +CCCNC(=O)c1ccc(Br)cc1F +COc1cccc(-c2ccc(C(N)=O)cc2)c1OC +CC(Sc1ccccc1Cl)C(=O)NC1CC1 +COC(=O)c1ccc(C(=O)Nc2ccc(OC)c(Cl)c2)cn1 +CCCC(C)(CO)NC(=O)NCC1(c2ccccc2)CC1 +Cc1nccc(C(=O)NCCc2c(F)cccc2F)n1 +Nc1ccccc1-c1nnc(NC(=O)c2cnccn2)s1 +COC(=O)CC(NC(=O)c1ccc(C)cc1)c1ccccc1 +CCN1CC(C(=O)N(C)Cc2n[nH]c3c2CCCCC3)CC1=O +Nc1ncc(S(=O)(=O)NC2CCCCC2)cn1 +CC(c1ccccc1)N(CC1CCC1)C(=O)c1cnccn1 +COCc1cccc(-c2nc3scc(C)c3c(=O)[nH]2)c1 +O=C(Cc1csc(-n2cccc2)n1)Nc1ccc(F)c(F)c1 +Cc1ccc2c(c1)N(C(=O)COC(=O)c1cc(F)ccc1F)CCO2 +Cc1cc(C(C)NC(C)Cc2ccsc2)c(C)o1 +O=C(NCc1ccsc1)N1CCN(Cc2ccccc2)CC1 +Cc1csc(=O)n1CCC(=O)Nc1ccc2c(c1)OCCCO2 +COc1cccc(NCC(O)c2ccc3c(c2)OCCO3)c1 +COc1ccc(NC(=O)NCCNC(=O)c2ccccc2Cl)cn1 +COCc1ccc(CNC(=O)c2cccc(C)c2)cc1 +COc1ccc2[nH]cc(C(=O)N(C)c3ccccc3)c(=O)c2c1 +CC(=O)c1c[nH]c(C(=O)NC(C)c2ccc3c(c2)OCO3)c1 +O=C(NCC(O)c1ccco1)Nc1ccccc1SC1CCCC1 +COC(=O)CCCC(=O)N1CC(c2ccc(F)cc2)CC1C +COc1ccc(CC(=O)Nc2c(C)ccc(N)c2C)cc1 +CCn1c(SC(C)C(=O)NC2CC2)nnc1-c1ccccc1 +CC(=O)Nc1cccc(NC(=O)N(C)Cc2cccc(C#N)c2)c1 +Cc1csc(NC(=O)c2ccc(COC(C)C)o2)n1 +CCCn1nnc(NC(=O)c2ccccc2Cl)n1 +CC(C)n1c(-c2ccc(Cl)cc2)ccc(C#N)c1=O +COCCOc1cc(C(=O)N=c2sccn2C)ccn1 +Cc1nnsc1C(=O)Nc1cnn(C2CCOCC2)c1 +Cn1ncc(S(=O)(=O)NCCN2CCOCC2)c1N +Cc1noc(C)c1CN1CCOC2C(Oc3cccnc3)CCC21 +N#Cc1ccc(-c2noc(-c3cc(-c4cccnc4)on3)n2)nc1 +Cc1cnc(CNC(=O)N2CCc3cc(F)ccc3C2)s1 +O=C(C1CC=CC1)N1CCN(c2ccccc2)CC1 +CC(=O)Nc1cc(C(=O)N(CCC#N)CC(C)(C)C)ccc1F +O=C(Nc1cccnc1)N1CCN(CC(F)F)CC1 +CC(c1cc2ccccc2o1)N(C)C(=O)c1csnn1 +CC(C)c1cc(C(=O)N2CCC(O)(c3cccnc3F)CC2)on1 +Cc1cc(NC(=O)CCc2ncc(-c3ccc(F)cc3)o2)no1 +CCOCC(=O)Nc1ccc(OCc2cccc(C#N)c2)c(Cl)c1 +COC1CCC(CC(=O)N2CCSc3ccc(Cl)cc32)CC1 +Cc1ccc(Oc2cc3c(cc2N)OCCO3)cc1C +O=C(Nc1ccccc1F)N1CCC(Cn2cccn2)CC1 +CCOc1ncccc1CN(C)C(=O)c1cnn2cccnc12 +O=C(CCC1CCCCC1)N1CCc2[nH]c(=O)sc2C1 +Cc1cc(NC(=O)c2cccc(-c3ccoc3)c2)n(C)n1 +COc1ccc(-c2noc(NCc3ccc(OC)cc3OC)n2)cc1 +Cc1nc2nc(C(C)C)[nH]c2cc1Br +CC(C)S(=O)(=O)c1ccc(F)c(C(=O)N=c2sccn2C)c1 +CN(C)C(=O)CCCc1nc(-c2ccc(Cl)cc2)no1 +CC1COCC(C)N1C(=O)c1cc2ccccc2o1 +CS(=O)(=O)NCCNc1nc2cc(Cl)ccc2s1 +COc1ccccc1C(=O)CNc1c(C)cc(C)cc1C +CC1(C)CN(Cc2nnc(-c3ccc(Cl)cc3Cl)o2)CCO1 +CNC(=O)c1nnc2c(-c3ccncc3)ccnn12 +COC(=O)CC1=C(C(=O)OC)C(c2ccccc2)N(C)C(=O)N1C +CCCc1cc(C(=O)NC2CCN(S(C)(=O)=O)CC2)[nH]n1 +COc1ccc(CC(=O)NCc2nc(-c3ccco3)n[nH]2)cc1OC +COc1ccc2c(c1)c1ncnc(N3CC(C)OC(C)C3)c1n2C +c1ccc2c(-c3csc(N4CCCC4)n3)c[nH]c2c1 +Cc1noc(COC2CCCN(C(=O)NCc3ccco3)C2)n1 +Cc1csc(=O)n1CCC(=O)Nc1ccccc1OC(F)(F)F +CC(NC(=O)Cn1c(=O)cnc2ccccc21)c1ccc(F)cc1F +Cc1csc(C2CN(Cc3cccc(Cl)c3Cl)CCO2)n1 +CC(c1ccco1)N(C)C(=O)CCCOc1ccc(F)cc1 +Cc1ccc(CN(C(=O)c2cn[nH]c2)C2CC2)cc1 +CC(=O)N1CCC(N(C(=O)Nc2cccc(C)c2)C(C)C)CC1 +O=C(COc1ccc2ccccc2c1)N1CCOCC1c1ncon1 +O=C(CCNC(=O)c1ccccc1Cl)Nc1ccc2c(c1)CCC2 +O=C(Nc1cccc(C(=O)N2CCCCC2)c1)c1cccc2ccoc12 +c1ccc2sc(NC3=NCN(C4CC4)CN3)nc2c1 +CN(Cc1ccccn1)C(=O)Nc1cccc(N2CCCC2=O)c1 +Cc1ccc(S(=O)(=O)NCCc2c(C)nn(C)c2C)c(C)c1 +CC1(C(=O)NCc2ccc(-n3ccnc3)cc2)CC1(Cl)Cl +CC1CCCCN1c1ncnc(N2CCCCCC2)c1N +Cc1[nH]c(=O)c(C(=O)N(C)Cc2ccccc2)c(C)c1N +Nc1ccccc1NC(=O)c1c(F)cccc1Cl +CC(Cn1cccn1)NC(=O)Cn1cccc(C(F)(F)F)c1=O +O=C(NCCC(c1ccccc1)c1ccccc1)c1cnccn1 +CC(C)(CO)Nc1ncc(Br)c2c(N)cccc12 +O=C(NCCNC(=O)c1cccs1)c1nc(C2CC2)no1 +Cc1ccc(S(=O)(=O)NCc2cnn3ccccc23)cc1 +CCn1c(C)cc(C(=O)Nc2ccccc2OC(C)C)c1C +CC(Sc1n[nH]c(=O)n1C1CC1)C(=O)NCc1ccccc1 +CC1CCCC(NC(=O)CCn2nnc3ccccc3c2=O)C1 +Cc1ccc2c(CSc3nncs3)cc(=O)oc2c1 +Cc1onc(-c2cccnc2)c1C(=O)NCc1ccccc1Cl +COCCN1CCN(Cc2cc(F)ccc2Br)CC1=O +CCn1cc(CN(C)C(=O)Nc2ccc(C(C)C)cc2)cn1 +COCc1cccc(CNC(=O)NC(C)(CO)C2CCCCC2)c1 +CN(CC1CCCO1)c1nccnc1N(C)CC1CCCO1 +CC(C)(C)CCNC(=O)CSc1nc2ccccc2[nH]1 +O=C(Nc1ccc(N2CCCC2=O)cc1)c1cccnc1 +CCOC(=O)c1nn(Cc2ccc(F)c(F)c2)c2ncccc12 +COc1cccc(C(=O)NCc2cccnc2-n2cccn2)c1O +CN(C)C(=O)CN(CC(F)(F)F)C(=O)Cc1cn2ccsc2n1 +O=C(Nc1ccccc1OCC1CC1)c1ccc(-n2ccnc2)nc1 +CCOCc1cccc(NC(=O)N(C)CCN2CCOCC2)c1 +COc1ccc2c(cnn2CCC(=O)NCc2c(C)nn(C)c2C)c1 +CC(NC(=O)c1scnc1C1CC1)c1ccccc1 +COc1ccc(OC)c(NC(=O)CC2C(=O)Nc3nc(C)nn32)c1 +Cc1ccc(CC(=O)N2CCC(c3nc4ccccc4[nH]3)CC2)s1 +CN(CCOc1ccccc1)c1ncnc2c1cnn2C +O=C(CCC(=O)Nc1ccccc1)Nc1ccccc1 +CCN(CC)C(=O)c1nc2c(s1)CCN(C(=O)CC(C)C)CC2 +CC(NCc1nccc(N)n1)c1nc(-c2ccccc2)cs1 +CSc1ccc(S(=O)(=O)NCCN(C)c2ccccc2)cc1 +CCN(C)C(=O)CCNC(=O)c1n[nH]c2ccccc12 +CSc1ccc(Cl)cc1NC(=O)NCCNC(C)=O +COc1ccc(COCC(=O)NCc2ccoc2)cc1 +CCC(=O)N1CCc2cc(CNC(=O)Nc3ccc(F)cc3)ccc21 +CC(C)CC(O)C1CCN(C(=O)c2ccc(N3CCCC3)cc2)CC1 +CC(C)CN1CC23C=CC(O2)C(C(=O)OC(C)C)C3C1=O +CCC(C#N)Oc1cccc(CNC(=O)Nc2nc(C)cs2)c1 +COc1cccc(N2CCN(C(=O)Nc3ccc(OC)nc3)CC2)c1 +Cc1cc(C)n(Cc2nc(-c3ccsc3)oc2C)n1 +CCCOc1ccc(NC(=O)C2CCCN2C(C)=O)cc1Cl +Cc1nc(-c2ccccc2OCC(=O)Nc2ccccc2C)no1 +CCC(OC)C(=O)N(c1cccc(O)c1)S(C)(=O)=O +O=C(NCC(=O)N1CCC(Cc2ccccc2)CC1)c1cnccn1 +Cc1cn2c3c(=O)[nH]c(=O)n(C)c3nc2n1CCCO +CC(CO)NC(=O)c1ccc(-c2cccc(C(F)(F)F)c2)o1 +CC(C)c1noc(C2CCCN2C(=O)NCc2ccccc2)n1 +CNc1ncc(C(=O)NCc2ccnc(OC(C)(C)C)c2)s1 +Cc1cc(CN2CCN(C(=O)C3(C#N)CCCC3)CC2)on1 +COC(C)(C)C(=O)N1CCCC(NC(=O)c2cnccn2)CC1 +N#Cc1cccc(NC(=O)c2cc3ccccc3o2)c1 +Cc1nc(-c2cccc(NC(=O)C3CCC3)c2)oc1C +OC(CN1CCOC(Cn2cccn2)C1)c1ccc(F)c(F)c1 +CC(=O)c1cccc(OC(C)C(=O)NC2CCC(C)CC2)c1 +CCOC(=O)c1csc2nc(-c3ccc(C)cc3)c(N)n12 +COC(=O)c1ccsc1COc1ccccc1N +Cc1nn(Cc2ccccc2)c(C(N)=O)c1Br +Cc1cc(F)ccc1CCNC(=O)NCCc1cccnc1 +CS(=O)(=O)c1cc(N)cc(C(=O)NC2CCCC2)c1 +Cc1cc(Cl)cc(C)c1CN1CCOC(c2cnn(C)c2)C1 +CC(O)CCN(C)C(=O)NCc1ccc2c(c1)OCO2 +CSc1ncc(Br)c(C(=O)Nc2ncccn2)n1 +COCCOc1ncccc1NC(=O)c1ccncc1F +Cc1ccc(-c2nnc(NC(=O)c3ccn(C)c(=O)c3)s2)c(C)c1 +O=C(CNC(=O)c1ccccn1)Nc1ccc(F)cc1 +O=C(c1cc(-c2ccco2)on1)N1Cc2cncnc2C1 +Cc1ccc(C(C)NC(=O)CCNC(=O)c2ccco2)cc1F +CCOc1c(OC)c(Cl)cc2c1C(CC)NCC2 +Cc1nc(C(=O)NCC#Cc2ccccc2C(F)(F)F)cs1 +Nc1ccn(CCCCOc2cccc(Cl)c2)n1 +CC1CCCN(C(=O)c2cnc(Cc3ccccc3)s2)C1 +COc1coc(C(=O)N2CCCCC2CCc2cccs2)cc1=O +O=C(N1CCCC(CO)(CC2CC2)C1)C1(c2ccccc2F)CC1 +CCC(CC)N(CCO)C(=O)c1ccc(C)nc1 +CNc1cnc(N(C)CCO)c2c(Cl)cc(Cl)cc12 +CNC(=O)COc1cccc(CC(=O)NCc2nc(C)sc2C)c1 +O=C(CCSc1ccccn1)Nc1c(O)cccc1F +COc1cc(C)nc(N2CCN(C(=O)C(C)OCC3CC3)CC2)n1 +CN1CC2CCN(C(=O)NC3CCCC3)CCC2S1(=O)=O +COCCCNC(C#N)c1cccc(Br)c1 +Cc1ccc(CNC(=O)NCc2noc3ccccc23)cc1 +Cc1ccc(S(=O)(=O)Nc2ccc(N3CCCC3=O)cc2)s1 +COc1cccc(C(=O)Nc2cccc3ccc(C)nc23)c1F +N#Cc1ccc(C(=O)OCCN2CCOC2=O)cc1 +CC(C)(C)CCC(=O)N1CCC(NC(=O)c2ccsc2)CC1 +CCn1cc(C(=O)Nc2ccccn2)c(=O)c2cc(Cl)ccc21 +Cc1cccc(C)c1NC(=O)COC(=O)c1ccc(Cl)cc1 +COc1cc(CNC(=O)COc2ccccc2Cl)ccn1 +Nc1ccc2c(NCCOCCO)ncc(Br)c2c1 +NC(=O)C1CCN(C(=O)c2occc2COc2ccccc2)CC1 +Cc1cccc(C)c1NC(=O)c1nnn(-c2ccc(Cl)cc2)c1C +CCOc1ncccc1CNC(=O)C1COc2ccc(F)cc2C1 +CC(C)Oc1ccc2c(C(=O)NCC3CCCO3)cc(=O)oc2c1 +CCCCN(C)C(=O)CCC(O)c1cc(C)ccc1C +CN(Cc1nc2ccccc2s1)S(=O)(=O)CCCCC#N +O=c1[nH]c(-c2cccnc2)nc2sc3c(c12)CCCCC3 +CCc1onc(C)c1NC(=O)NCC(O)(CC)CC +CCn1c(-c2ccc(OC(C)C)cc2)ccc(C(C)=O)c1=O +Cc1ccc(N2CCN(C(=O)C3(Cn4cccn4)CC3)CC2=O)cc1 +COc1ccc(COC(=O)c2nccnc2N)cc1 +COc1ccc(C(=O)NCCOc2ccc(-c3ccccc3)nn2)cc1 +O=C(c1ccc2c(c1)OCCO2)N1CCCc2cccc(F)c21 +Cc1ccsc1C(=O)Nc1cccc(N2CCCS2(=O)=O)c1 +COCCn1ccc(NC(=O)NC2(c3ccccc3F)CC2)n1 +Cc1cnn(C(C)C(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)c1 +CCOc1ccccc1OCC(=O)Nc1ccccc1-n1cnnn1 +COC(CNC(=O)c1cc(C)on1)c1ccsc1 +O=C(c1ccsc1)N1CCc2onc(-c3ccccc3)c2C1 +Cc1ccc(CN(C)Cc2nccs2)cc1F +CCN(C)S(=O)(=O)NCc1nc(-c2ccc(Cl)cc2)no1 +O=C(COC(=O)C1CCC1)Nc1ncc(Cl)cc1Cl +CCN1CC(C(=O)NCc2ccc3c(c2)CCC3)CC1=O +Cc1ccc(N2CCC(Sc3ncc[nH]3)C2=O)cc1 +Cc1ccc(NC(=O)CC2Oc3ccccc3NC2=O)c(F)c1 +CCNC(=O)CNC(=O)c1cc(OC)ccc1O +Cc1cc(NC(=O)NCC2(O)CCCCC2)n(C2CCCCC2)n1 +CN(Cc1nc(-c2cccnc2)no1)Cc1cc(F)c(F)cc1F +CCNC(=O)COC(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +CC(C)(C)Oc1ccc(C(=O)N2CCC(=O)CC2)cc1 +COc1ccccc1C1(C(=O)NCCc2ccsc2)CC1 +COc1ccc(N)cc1CNC(=O)c1cc(Cl)cc(Cl)c1 +Cc1n[nH]cc1CN1CCCCC1c1nc(-c2ccccc2)no1 +CC(C)(C)OC(=O)NC1CCNC1c1cnc[nH]c1=O +Cn1nc(C(=O)Nc2cccc(C(N)=O)c2)c(=O)c2ccccc21 +CCn1nnc2cc(C(=O)Nc3cccnc3)ccc21 +COC(=O)c1cc(CN2CCOCC2C2CC2)c(C)s1 +O=C(Cc1n[nH]c2ccc(F)cc12)NCCc1ccncc1 +CC(C)C(NC(=O)c1ccnc2[nH]ccc12)C(=O)Nc1nccs1 +Cc1c(C(=O)N(C2CC2)C(C)c2ccco2)cnn1C +CCn1c(CNCc2ccccc2COC)nc2ccccc21 +CC(C)Cc1cn[nH]c1C1CCCN(C(=O)Cc2cccs2)C1 +CC(C)n1nc(C(=O)N2CCN(CCO)CC2)c2ccccc2c1=O +CCOc1ccc(-c2nc(-c3cccc(N)c3)no2)cc1OCC +COc1c(C)cc(CNc2cccc(N3CCCC3=O)c2)cc1C +Cc1ccc(-c2nn(C)c(=O)c3ccccc23)cc1 +Cc1c(C(=O)Nc2ccnn2C(C)C)cnn1-c1ccccc1 +CC(C)(C)c1nc(C#N)c(S(=O)(=O)c2ccc(F)cc2)o1 +CC(=O)NCC1CCCN(C(=O)Nc2cnc3c(c2)c(C)nn3C)C1 +COc1ccc(NC(=O)c2cccc(F)c2N)cc1 +Cn1ccc(C(=O)N2CCC(c3nc(-c4ccccn4)no3)C2)n1 +CC(C)(C)n1ncc2c1CCCC2NC(=O)Nc1nccs1 +CSc1nc(C(=O)OCc2nncn2C2CC2)c2ccccn12 +CCOc1ccc(C#N)cc1NC(=O)c1scnc1C +COC(=O)CNS(=O)(=O)c1c(C)c(C)cc(C)c1C +CC(C)(C)NC(=O)Cn1c(-c2ccc3c(c2)OCCO3)csc1=O +NS(=O)(=O)c1ccc(NCCc2ccsc2)cc1 +C=CCN(CC=C)C(=O)CSc1nc(C)c(Cl)c(C)c1C#N +NC(=O)c1c(NC(=O)Cn2cnnn2)sc2c1CCCC2 +Cc1ccc(Cl)c(NC(=O)Cn2nnc3c(C)n(C)nc3c2=O)c1 +O=C1COc2cc(NC(=O)C3(Cc4ccccc4)CCC3)ccc2N1 +Cc1ccc(F)cc1NC(=O)C(C)NC(=O)c1ccccc1 +Cc1sc2ncn3nc(Cn4nc(C(F)F)cc4C)nc3c2c1C +Cc1nn(C)c2c(=O)n(CC(=O)NCc3ccccn3)ccc12 +Cc1nn(C)cc1C(=O)Nc1c(Cl)cccc1Cl +CCOCCCNC(=O)CN1CC(C)Sc2ccccc21 +CN(CC(F)(F)F)C(=O)Nc1cc(F)ccc1F +CCC(C)n1ncc(C(=O)NCc2ccccn2)c1C1CC1 +O=c1oc2cccnc2n1CCSc1nncn1C1CC1 +CCCC1CN(c2ncccc2C(=O)NC)CC1NC(=O)CCO +CC(C)(C)NC(=O)COc1ccc2c(c1)OCO2 +Cc1c(OCC(=O)NCc2ccc(Cl)cc2)c(=O)ccn1C +CCS(=O)(=O)c1nnn(-c2nnc(COC)s2)c1N +COC(=O)c1cccc(NC(=O)c2ccc(C)c(NC(C)=O)c2)c1 +O=C(NCCO)c1ccc(OCc2csc(C3CCCC3)n2)cc1 +COCc1ccc(CNC(=O)c2ccnc(OC3CCC3)c2)cc1 +COc1ccc(OCC(=O)N(CC(N)=O)C(C)C)cc1 +O=C1CCN(S(=O)(=O)c2cc(Cl)ccc2Cl)CCN1 +Nc1cc(-c2csc(-c3c[nH]cn3)n2)ccc1F +O=C(Nc1ccc(-n2cncn2)nc1)NC1CCCCNC1=O +Cc1cnn(-c2ccc(C(=O)N(C)CCc3ccc(F)cc3)cc2)c1 +CCCS(=O)(=O)NCc1ccccc1C#CCO +CCOc1cc(NC(=O)CNC(=O)c2ccccc2C)ccc1OC +CCOC(=O)CCCNC(=O)Nc1ccc(Cl)cc1C +CCC(C)C(C)NS(=O)(=O)c1ccnc(N)c1 +COCC(=O)N1CCN(c2ccc(Cl)cc2C#N)CC1 +COc1ccc(Br)cc1CNC(=O)c1ccncc1 +O=C(CCCOc1cccc(F)c1)NCc1cscn1 +Cc1nn(C)cc1CN1CCN(Cc2ccc(Cl)cc2)C(=O)C1 +Cc1noc(C)c1C(C)NC(=O)C1CCCCN1C(=O)c1ccco1 +O=C(NCC(F)(F)F)c1ccnn1-c1ccccc1 +CC(=O)N1CCCC(c2ncc(C(=O)N3CCCCC3)c(C)n2)C1 +COc1ccc(O)c(C(=O)OCC(=O)Nc2ccc(F)c(F)c2)c1 +O=C(Nc1ccc2oc(=O)ccc2c1)c1csc(NC2CC2)n1 +C=CCOC(C)C(=O)Nc1ccccc1CC(=O)NC +O=C(NCc1ccc(OCC2CC2)cc1)c1ccc2cncn2c1 +COC(=O)c1sccc1CSc1nc2nc(C)cc(C)n2n1 +Cc1ccc(C(=O)NCC(=O)Nc2cccc(-c3cn[nH]c3)c2)cc1C +CC(C(=O)Nc1cccnc1)N(c1ccccc1)S(C)(=O)=O +CCOc1cc(C)ccc1S(=O)(=O)N=c1cc(C)cc[nH]1 +CC(=O)NC(CC(=O)Nc1ncc(C(N)=O)s1)c1ccccc1 +CCCCNC(=O)C1CCCN(C(=O)Nc2ccc(F)c(C#N)c2)C1 +COCC(NC(=O)c1ccc(OC)c(-c2ccccc2)c1)C(N)=O +CC(C)COc1cccc(NCC(=O)N2CC(C)OC(C)C2)c1 +CCOC(=O)NCCC(=O)NC1(C#N)CCCCC1 +CC(=O)c1cc(Br)ccc1NC(=O)c1scnc1C +CCOCC(=O)N1CCCN(S(=O)(=O)c2ccccc2)CC1 +CCOc1ccccc1NCC(=O)N1CCc2ccccc21 +CC(C)N(C)S(=O)(=O)c1cccc(C(=O)N2CCCCCC2)c1 +CCCC(=O)N1CCCC(C(=O)Nc2ccc3c(c2)CCC(=O)N3)C1 +O=S(=O)(NCc1ccccc1)NCC1OCCc2ccccc21 +Cc1n[nH]c(-c2cccc(CNC(=O)CC(C)C(C)C)c2)n1 +CCOC(=O)CCN1C(=O)COc2ccc(Br)cc21 +Cc1csc(C2(NC(=O)Cc3ccc4c(c3)OCO4)CCCC2)n1 +CC(C)COc1cncc(N(C)C2CCN(c3ncccn3)CC2)n1 +Cc1ccc(CNS(=O)(=O)c2cccc(C(N)=O)c2)cc1F +N#Cc1cc(-c2ccccc2)oc1NC(=O)c1cccs1 +CC(=O)c1sc(N2CCc3sccc3C2)nc1C +Cc1ccc(N)c(C)c1NC(=O)COc1ccccc1 +COc1ccc(C(=O)CCC(=O)N(C)c2ccccc2)cc1 +CCc1ccc(C(=O)NC(C)c2ccc(S(N)(=O)=O)cc2)o1 +COc1cc2c(cc1OC)C(C=Cc1ccco1)=NCC2 +Cc1nn(C)c2[nH]c(-c3cccn3-c3cccnc3)nc12 +CN(CC1COc2ccccc2O1)C(=O)COc1ccccc1C#N +CC1Sc2ccc(C(=O)NCCO)cc2NC1=O +O=C(c1cc(=O)c(OCc2ccccc2)co1)N1CCOCC1 +Cc1ccc(CNC(=O)C2CCCO2)c(OCC2CC2)c1 +CC(C)CC(=O)Nc1ccc2c(c1)nc1n2CCN(C2CC2)C1 +Nc1cc(-c2nnnn2CC2CCOC2)ccc1Br +CN(Cc1ccco1)C(=O)C1CC(=O)N(c2ccccc2)C1 +O=C1NCCN(CC=Cc2ccco2)C1c1ccc(F)cc1 +Cc1ccc(S(=O)(=O)NCc2[nH]ncc2Br)cc1F +CCCCOC(=O)c1cn(-c2ccccc2)c(=O)c2ccccc12 +O=c1ccn(CCOc2ccc(Br)cc2)c(=O)[nH]1 +Cc1ccc(NC(=O)Oc2ccccc2)cc1N1CCCC1=O +NC(=O)CSc1ccccc1NC(=O)CCC1CCCC1 +N#Cc1c(F)cccc1S(=O)(=O)N1CCC(Nc2ccccc2)C1 +CCOC(=O)Nc1nnc(-c2cccs2)s1 +O=C(Cn1cnnn1)N1CCCC2(C1)C(=O)Nc1ccccc12 +COc1cccc(C(=O)Nc2ccnn2-c2ccncc2)c1F +CC(C)CNC(=O)NCc1cc(Br)c2c(c1)OCCO2 +O=C(c1ccncc1)N1CC2CC3CC(C2)CC1C3 +COC(=O)N1CCN(CCNC(=O)C(C)(C)C)CC1 +COc1cc(OC)cc(C(=O)Nc2ccccn2)c1 +CCC(=O)NC1CCOc2ccc(C(O)CC(C)C)cc21 +O=C(CCn1cncn1)NCc1ccc2ccccc2c1 +Cc1ccc(-n2nnc(C(=O)NC(C)C)c2C2CC2)cc1 +CC(C)NC(=O)CCNC(=O)c1cc2ccoc2s1 +COc1ccc(OC)c(S(=O)(=O)NC2CCCCC2)c1 +C=CCN(Cc1ccc(OC)cc1)C(=O)c1ccc(F)cc1 +Cc1cc(NC(=O)C(C)N2CCN(c3ccccc3)CC2)no1 +CNc1nc(-c2sc(N3CCCCC3C)nc2C)cs1 +Cc1cnn(CC2CN(CC(=O)N(C)Cc3cnn(C)c3)CCO2)c1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)N(C)CC1CC1 +Cn1cnc(CNC(=O)N(CC2CCCCC2)C2CC2)n1 +CCOC(=O)C1CCC(NC(=O)Nc2ccc3c(c2)COC3)CC1 +COc1ccc(OC)c(NC(=O)CCCn2cccc2)c1 +CCOc1ccccc1-c1cc(CO)c(=O)n(C)n1 +Cc1cc(C)c(NC(=O)c2ccccc2F)c(C)n1 +COc1cc(C(=O)Nc2ccc(CC#N)cc2)cc(OC)c1OC +CCCNC(=O)c1cccc(C(=O)N(C(C)C)C2CCOCC2)c1 +O=C(NCCC1=CCCCC1)NCc1cccs1 +Cc1ccc(C(=O)CSc2nnnn2-c2ccccc2)cc1C +Cn1cnc2cc(OC(=O)CCSc3ccccc3)ccc21 +CC1CCCN(C(=O)CC2CSc3nc(C(C)C)cc(=O)n32)C1 +COCCOc1cccc(NC(=O)c2nc3nc(C)cc(C)n3n2)c1 +Cc1ccsc1C(=O)N(C)CC(=O)NC1CC1 +CC(C)CN1CCOC(COC(=O)c2cccc(F)c2)C1 +O=C(CCC1CCCCC1)NCc1cccnc1-n1cncn1 +CN(CCC#N)C(=O)c1ccccc1Br +CCOC1COCC1NC(=O)c1n[nH]c(N)c1-c1ccccc1 +Cc1ccc(NC(=O)NC(C)C(C)CO)cc1C(=O)NC(C)C +Cc1cccc(S(=O)(=O)Nc2cc(C)ccc2O)c1 +O=C(Cc1ccccc1)NCC1Cn2cc(-c3ccccc3)nc2CO1 +C=CCn1c(SC(C)C(N)=O)nc2ccccc21 +CCOCC(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +CC1CCc2nc(C(N)c3ccc(F)cc3)sc2C1 +Cc1cc(NC(=O)c2csc(-c3ccccc3)n2)[nH]n1 +CCN(Cc1ccc(Cl)c(Cl)c1)C(=O)c1ccc(=O)n(C)c1 +O=C(CCSc1nnc(-c2cccc(Cl)c2)o1)N1CCCC1 +CCc1cc(NCCCC(F)(F)F)n2nccc2n1 +COC(=O)C(NC(=O)c1c[nH]c2ccccc2c1=O)C(C)C +CC(Oc1ccccc1C(C)C)C(=O)N1CCNCC1 +CC(=O)Nc1ccc(SC(C)C(=O)NCCO)cc1 +CC(C)(C)c1nc(-c2cnccn2)sc1CC#N +c1csc(CCNCc2nc3ccccc3s2)c1 +COCC(NC(=O)C1(c2ccc(C(C)(C)C)cc2)CC1)C(N)=O +O=C(CNC1=NS(=O)(=O)c2ccccc21)Nc1ccc(F)cc1 +CCc1cnc(CN(C)C(=O)c2cn(C)nc2C(C)(C)C)s1 +Cc1noc(C)c1CC(C)NC(=O)Nc1scnc1C(C)(C)C +CC(=O)Nc1ccc(CCNC(=O)NCCC2=CCCCC2)cc1 +Nn1c(-c2cccc(Cl)c2)nc2ncccc2c1=O +Cc1ccc(CN(C)C(=O)c2cccc(N3CCNC3=O)c2)o1 +CC(=O)C(NC(=O)CSc1nnc(C2CC2)n1C)C(C)C +Cn1c(C2CC2)nc2cc(C(=O)Cn3cc(N)cn3)ccc21 +CCOC(=O)c1sc(NC(=O)c2ccc(OC)cc2)c(C#N)c1C +COCCc1noc(-c2csc(Cc3ccccc3)n2)n1 +COC1CCN(C(=O)C2CC2c2ccc(Cl)cc2Cl)CC1 +COc1cccc(C2NCCc3c(C)ccc(F)c32)n1 +FC(F)(F)c1cccc(NCc2ccncc2)c1 +CCOc1ccc(-c2ccc(C#N)c(=O)n2CCOC)cc1 +Cc1ccc(C(=O)Nc2cc(F)ccc2Cl)c(C)n1 +Cc1nc(CN2CCOCC23CCN(c2ncccn2)CC3)cs1 +CCOc1ccc(Br)cc1NC(=O)CCC(=O)OC +COc1ccc(C)cc1C(=O)CNC(=O)CCc1ccccc1 +CC1=C(C(=O)Nc2ccc(F)c(F)c2)C(c2ccccc2)NC(=O)N1 +Cc1cc(C)c(CNC(=O)c2c(C)oc3ccn(C)c(=O)c23)c(C)c1 +COc1ccc(NC(=O)c2cccc(-n3cccc3)c2)c(OC)c1 +CCCCNC(=O)c1cc(S(=O)(=O)NC(C)(C)C)ccc1C +N#CC(c1ccccc1)N1CCN(C(=O)c2ccc[nH]2)CC1 +Cc1cccc(CN2CC(OCc3csc(C)n3)C3COCC32)n1 +Cc1cccc(CNC(=O)N2CCN(c3ccnc(C)n3)CC2)n1 +CCCNC(=O)Nc1cc(S(=O)(=O)CC)ccc1O +CC(C)S(=O)(=O)NCCOc1cccc(N)c1 +Cc1ccc(C)c(C(=O)NCC(O)c2ccc3c(c2)CCO3)c1 +Cc1cc(-n2nc(-c3ccncc3)nc2C2COCCO2)ccn1 +COC(=O)CC(NC(=O)c1cn2ccc(C)cc2n1)c1cccs1 +Cc1cc(OCC(=O)NCC2CCCO2)cc(C)c1Br +CC(C)(C)OC(=O)N1CCCC1C(=O)Nc1ccccn1 +O=C(c1ccc(OCC(F)F)nc1)N1CCCC1c1ccco1 +O=C(COC(=O)c1cc2ccccc2o1)c1ccccc1 +COCCCCNc1ccc(C(=O)N2CCOCC2)c(Cl)c1 +CC(C)C(C)(C#N)NCc1c(F)cc(F)cc1F +COc1ccc(C)cc1NC(=O)Oc1ccc(C#N)cc1 +N#Cc1ccc(OC(=O)Cc2ccccc2Cl)cc1 +Nc1ccc(Cl)c(-c2nc3cc(F)ccc3[nH]2)c1 +CC(c1cccnc1)N(C)C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1cccc(CNC(=O)c2cc(F)cc(F)c2)c1 +Cc1noc(C(C)C)c1C(=O)N=c1[nH]c2cc(Cl)ccc2n1C +Cc1ccccc1-n1cnc(C(=O)NCCC2OCCO2)n1 +COc1ccc(C2CC(c3ccccc3C)n3ncnc3N2)cc1 +Cc1ccccc1CC(=O)OCC(=O)N(C)c1ccccc1 +CNc1ccc(Cl)cc1C(=O)NCc1cc(C)on1 +CCOc1ccc(C(=O)NCC(F)(F)F)cc1OC +CC(=O)Oc1c[nH]c2ccc(Br)cc12 +O=C(COC(=O)c1ccccc1SC(F)F)c1ccc[nH]1 +COc1cc(C)sc1C(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +CN(c1ccc(C(=O)NC2CCCCC2)cc1)S(C)(=O)=O +Cc1ccc(NC(=O)Nc2c(C)cccc2C)cc1 +COc1ccc(C(=O)C(C)OC(=O)c2ccc(NC(N)=O)cc2)cc1 +Cn1c(C(=O)N2CCC3(CC2)OCCO3)ccc1-c1ccc(F)cc1 +COc1ccc(Cn2cc(NC(=O)c3cc4cccnc4[nH]3)cn2)cc1 +CCc1ccc(NC(=O)Nc2ccn(CCOC)n2)cc1 +Cn1ncc2c(N3CCCN(C(=O)c4ccccn4)CC3)ncnc21 +O=C(CC1(n2cccc2)CCCCC1)Nc1cccnc1 +CC(C)C(=O)Nc1ccc(NC(=O)Cn2cnnn2)cc1 +CNS(=O)(=O)c1ccc(CNC(=O)NC2CC2)cc1 +N#CC1(C(=O)Nc2cc(CC3CCCCC3)n[nH]2)CCC1 +CCOCCOCc1cc(Br)cs1 +CCC(CC)C(=O)N1CCNCC1c1ccccc1 +CC(C)c1ccc(C(=O)Nc2cccc(F)c2)c(N)n1 +O=C(COc1cccc(Cl)c1)Nc1ccc2c(c1)OCO2 +COC(=O)c1ccc(NC(=O)Cn2nnc3ccccc3c2=O)cc1 +CC1CN(Cc2c(O)c(=O)cc(CO)n2C)CC(C)O1 +CC1CCCCC1NC(=O)c1ccc(S(=O)C(C)C)cc1 +CN(C)S(=O)(=O)c1ccc(CCC(=O)Nc2ccccc2)cc1 +Cc1noc(C)c1CCC(=O)N1CCN(C(C)C(=O)NC2CC2)CC1 +COc1ccc(Cn2c(=O)ccn(C)c2=O)cc1Br +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)C1CCCC1 +CC1Oc2ccc(NC(=O)NC3CCCCC3C)cc2NC1=O +Cc1cc(CC(=O)NC2CCC(C(C)C)CC2)n[nH]1 +CCCN(CCC)C(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 +COCCN(CC(F)(F)F)C(=O)Cc1c(C)nn(C)c1C +CCCc1nnc(NC(=O)N(C)Cc2ccccc2OCC)s1 +CCOc1ccccc1NCC(O)c1ccc(OC)cc1 +Cc1cccc(COC2CCCN(C(=O)c3ccc(F)cc3)C2)c1 +CNC(=O)c1cc(C)ccc1NC(=O)CCc1c(C)nn(C)c1C +O=S(=O)(NCCc1ccccc1)c1ccc(F)c(F)c1 +CC(CC#N)N(C)C(=O)Nc1cccc(OCc2cccc(F)c2)c1 +CC(=O)c1csc(C(=O)N2CCCC2C(C)(C)O)c1 +COc1cccc(SCC(=O)c2ccc(O)c(NC(C)=O)c2)c1 +O=C(c1ccco1)N1CCC(n2cnc3ccc(F)cc32)CC1 +Cc1ccc2c(c1)c1ncnc(N3CCCC3)c1n2C +CCC(C)(C)c1nnc(NC(=O)NC(C)Cn2cncn2)s1 +CN(Cc1ccsc1)c1nnnn1-c1ccccc1 +CC1=C(C(=O)NCc2ccnc(OC3CCC3)c2)CCCO1 +COc1ncccc1CNC(=O)C(C)NC(=O)Nc1ccccc1 +CNC(=O)c1nc(CC(=O)Nc2cccc(C(F)(F)F)c2)no1 +CC(C)(C)c1cc(C(=O)N(CC2CCOC2)C2CC2)[nH]n1 +CC(C(=O)Nc1ccc(N2CCNC2=O)cc1)c1ccsc1 +Cc1cc(C(=O)Nc2cccc(N3CCCCCC3)c2)[nH]n1 +CS(=O)(=O)c1ccc(CC(=O)Nc2ccccc2Cl)cc1 +CC1(NC(=O)NC2CCCc3occc32)Cc2ccccc2C1 +CCC(C)NC(=O)Cc1csc(Nc2cccc(C)n2)n1 +CC(=O)Nc1nc(Cn2nc(C)c(C)c(C#N)c2=O)cs1 +O=C(Nc1ccnn1-c1ccc(Cl)cc1)c1scnc1C1CC1 +CN(C)C(=O)C1CN(C(=O)c2ccc(F)cc2)c2ccccc2O1 +Cc1ncc(CN(C)C(=O)NCC2CCOC2)s1 +CCOC(=O)Nc1cccc(C(=O)N(C)Cc2cccc(F)c2)c1 +CC(C)CCn1c(SCC(=O)N2CCOCC2)nc2ccccc21 +COc1ccc(OC)c(C(C)Nc2ncnc3sccc23)c1 +Cc1cccc(NC(=O)CCn2c(=O)[nH]c(=O)c3ccccc32)c1C +Cc1ccc(CC(=O)NC2CS(=O)(=O)c3ccccc32)o1 +Nc1ccc(S(=O)CCCOCC(F)(F)F)cc1 +O=C(Nc1cc(F)ccc1Cl)N1CCN(Cc2ccncc2)CC1 +c1ccc(CCCNc2nnc(C3CCC3)o2)cc1 +C=CCC(C(=O)OC)C1CCN(C(=O)OC(C)(C)C)CC1 +Cc1c(CO)nnn1-c1cccc(C(=O)OC(C)C)c1 +CC(C)CCNC(=O)COc1ccc(N)cc1F +COCC(Nc1cc(-c2ccccc2)nc2ccnn12)c1ccccn1 +CC(C(=O)NCc1ccc(-n2cccn2)nc1)n1cnc2ccccc21 +CCN(CC)S(=O)(=O)NC(C)Cc1ccccc1Cl +CCc1ccccc1NC(=O)COc1nccc(C)n1 +Cc1cc(CS(=O)(=O)c2ccccc2Br)on1 +Cc1oc(-c2cccs2)nc1CC(=O)Nc1ccnc2ccnn12 +Cc1cc(NC(=O)c2ccco2)n(Cc2ccccc2)n1 +CCCn1nc(-c2nn3c(-c4cccs4)nnc3s2)cc1C +O=C(C1CCC1)N1CCN(CC2CCCO2)CC1 +O=C(CCc1ccco1)NCc1nncn1-c1ccccc1 +Nc1cc(N2CCCCS2(=O)=O)ccc1Cl +Cc1ccsc1C(=O)NCC(C)N(C)C(=O)c1sccc1C +O=C(Nc1cccc(F)c1)N1CCn2nnc(COCC3CC3)c2C1 +CCC(NC(=O)NC1(C)Cc2ccccc2C1)C(=O)N1CCOCC1 +O=C(CN1CCN(Cc2ccccc2)C1=O)NCC1CCCCC1 +CCn1ncc(C(=O)N2CCCC(CCc3ccc(F)cc3)C2)c1C +Cc1nn(C)c2ncc(C(=O)NCc3cnn(C)c3)cc12 +Clc1ccc(Cc2noc(CCc3cccnc3)n2)cc1 +CSc1cccc(CN(C(=O)c2cccc(C#N)c2)C(C)C)c1 +CC(C)(C(=O)NC(CO)C(C)(C)C)C1=NC(C(C)(C)C)CO1 +O=c1c2sccc2ncn1CCc1ccccn1 +CCCNC(=O)CN(C)C(=O)CN1CCCc2cccc(F)c21 +COCCNC(=O)c1cc2c(=O)n(C)ccc2n1C +COc1ccc(NC(=O)Nc2ccn(Cc3ccccc3)n2)cc1 +CCOC(=O)C1=C(C(C)C)NC(=O)NC1c1ccco1 +Cc1ccc(NC(=O)Cn2c(=O)oc3ccccc32)cc1Cl +Cc1cnc(CCNC(=O)COc2ccc(C(N)=O)cc2)s1 +CC(=O)c1cccc(S(=O)(=O)NC2CCCCC2C)c1 +CCOc1ccc(CC(=O)Oc2cccc(C(=O)NC)c2)cc1 +CCn1cc(Br)cc1C(=O)N(C)CC(=O)NC(C)C +Cn1cc(CCNC(=O)N2CCN(c3cc(C#N)ccn3)CC2)cn1 +Cn1ncc2c1CCc1sc(NC(=O)c3cccs3)nc1-2 +CCCC(C)(NC(=O)c1occc1C)C(=O)OC +O=C1CCCCCN1Cc1cc(F)ccc1C(F)(F)F +FC(F)(F)c1nn(Cc2csc(C3CC3)n2)c2ccncc12 +O=C(CN1CCN(Cc2nnc(C3CCC3)o2)CC1)N1CCCC1 +CCC(C)N(CCOC)c1ncc(N)cc1C(N)=O +CCCC1CN(C(=O)CCc2cnn(C)c2)CCO1 +CCc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)cc1 +Cc1ccc(-n2cnc(C(=O)NC3CCCc4ccccc43)n2)cc1 +COCCNC(=O)c1cc(=O)c2cc(N)c(C)c(C)c2o1 +CC1CCN(C(=O)CCOc2ccccc2)C(C)C1 +COc1ccc(-c2ccc(C(=O)CCN3CCOCC3)cc2)cc1 +COC(=O)Cn1ncc(N2CCCC(C)C2)c(Cl)c1=O +Cc1ccc(CN(Cc2ccco2)C(=O)c2ccc(F)cc2)o1 +CC(=O)Nc1nc(C(=O)N2CCCC(n3nc(C)nc3C)C2)cs1 +O=C1CCC(NC(=O)c2cc(Cl)ccc2OC(F)F)CN1 +Cc1cccc2sc(C(=O)NCC(C)(C)C)nc12 +CCOc1ccc(C(=O)NCc2cccc(OC)c2)nn1 +Cc1ccc(C(O)c2ccc3c(c2)n(C)c(=O)n3C)cc1 +Cc1cc(C)c(S(=O)(=O)NCC(C)O)cc1Br +CCCC(=O)Nc1cccc(NC(=O)C2CCCN2C(=O)CCC)c1 +CC1CC1C(=O)Oc1ccc(NC(=O)c2ccco2)cc1 +O=C(NCCOCC(F)(F)F)Nc1ccccc1N1CCCCC1 +CC(C)c1ncc(Cl)c(C(=O)NCC(=O)NC2CC2)n1 +CC(C)C1OC(NC(=O)Nc2ccccc2F)=NC1=O +CCn1cnnc1CNC(=O)Nc1ccc(Cl)c(F)c1 +CC(C)CNC(=O)C1CC(=O)N(Cc2ccc(F)cc2)C1 +Cc1cnc(NC(=O)N2CCN(c3cccc(Cl)c3)CC2)s1 +CCOc1ccccc1NC(=O)NCc1ccccc1-n1ccnc1 +Cc1ccc2oc(C(=O)NC3CCCCCC3)cc2n1 +CCc1ccccc1CNC(=O)NCCc1nc(C(C)C)no1 +CCn1nc(C)c2nc(C)nc(NCCCn3cccn3)c21 +NC(=O)CCOc1ccccc1NC(=O)N1CCc2sccc2C1 +CC(C)c1c(C(=O)Nc2nccs2)cnn1-c1ccc(Cl)cc1 +CCc1nc(CCNC(=O)Nc2ccc(F)c(C)c2)cs1 +COCC1(C(=O)NC2CCN(c3ncccc3C#N)CC2)CCC1 +CCc1ccc(C(=O)NC(C)Cn2ccnc2)cc1 +CC(C)C1CCc2ccccc2N1C(=O)c1ccncc1 +CC(C)NC(=O)c1ccccc1S(=O)c1ccccc1C#N +CC(=O)c1cccc(NS(=O)(=O)c2cc(C)ccc2C)c1 +O=C(NCc1ccccc1)NCc1nnc2ccccn12 +O=C(CN1CCOC2CCCC21)NCc1ccccn1 +CCNC(=O)c1ccc(NC(=O)c2ccc(OC(C)C)nc2)c(C)c1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)C1CC(=O)N(C(C)C)C1 +Cc1oc(C)c(C(=O)NC(C)c2cccs2)c1C +COc1cccc(C(=O)Nc2ccc(-c3nccc(C)n3)cc2)c1F +O=C(CCc1ccccn1)NCc1cc(Br)cs1 +Cc1ccc(CNC(=O)N2CCC3(CC2)OCCO3)cc1F +CC1CN(c2nccc(C(F)(F)F)n2)CCC1(O)C1CCOCC1 +CCC(C)c1csc(N(C)C(=O)CCn2cncn2)n1 +COc1ccc2c(c1)CCN(C(=O)c1cnn3c1OCCC3)C2 +Cc1ccc(C(=O)NCc2ccc(CN3CCOCC3)cc2)n1C +O=C(NCc1ccccc1F)c1ccc2cc[nH]c2c1 +Cc1cc2ncn(S(=O)(=O)c3ccccc3)c2cc1C +CC1CCc2nc(CN(C)CC3CCCCO3)sc2C1 +O=C(NCc1cccnc1)c1cc2sccc2[nH]1 +CN(Cc1ccc(C(F)(F)F)cc1)C(=O)c1ccc(=O)[nH]c1 +Cc1nc(-c2ccccc2OCC(=O)N2CCCCCC2)no1 +O=C(NCC1CCCO1)c1ccc(NCC(=O)N2CCCCC2)cc1 +O=C(NCc1nccs1)N1CCCC(CN2CCOCC2)C1 +O=C(Nc1cc(F)c2[nH]c(=O)ccc2c1)Nc1ccccc1Cl +CSc1nc2ccccc2c2nc(-c3ccco3)nn12 +Cc1nc(CC(=O)Oc2ccc3c(C)cc(=O)oc3c2)cs1 +CN(C)C(=O)CN1CCN(c2ncnc3c2cnn3CCC#N)CC1 +O=C(NCC(O)c1ccccc1F)NC1CCC2(CC1)OCCO2 +CCCC(=O)NCc1nc2ccccc2n1CC(C)C +Cc1cc(CSc2nc(C)nc(C)c2C#N)c2ccccc2n1 +COc1ccc(S(=O)(=O)NCCn2ncccc2=O)cc1F +O=C(NCc1cccc2ccccc12)C1CCCN(c2cnccn2)C1 +O=C(Nc1ccc(-c2nc3ccc(F)cc3[nH]2)cc1)C1COCCO1 +CCC(=O)Nc1cccc(C(=O)Nc2ccc3c(c2)CCC3)c1 +COCc1ccc(CNC2CCCN(c3ccccc3F)C2=O)cc1 +NS(=O)(=O)c1cc(S(N)(=O)=O)c(Br)cc1Cl +COc1ccc(F)c(NC(=O)c2sc(C)cc2OC)c1 +COc1ccc2c(CC(=O)N3CCc4sccc4C3)coc2c1 +CCOC(=O)CN(C(=O)c1ccc(Cl)cc1F)C1CC1 +CS(=O)(=O)NC1CC(=O)N(c2ccccc2Cl)C1 +COc1ncccc1NC(=O)N1CCC(CCO)C1 +COCCc1noc(CSc2nc3cc(C)ccc3o2)n1 +CNc1nc(CNC(=O)Nc2ccccc2Cn2cccn2)cs1 +Cc1cc2ccccc2n1CCC(=O)N1CC2CC(O)C(O)CC2C1 +CN(CCOc1cccc(Cl)c1)C(=O)c1ccoc1 +CCCn1cc(-c2cc(-c3cc(CC)n[nH]3)c(C#N)c(N)n2)c(C)n1 +CC1CN(Cc2cccc(CNC(=O)NCCO)c2)CCO1 +O=C(Nc1cccnc1)c1cc(-c2ccncc2)nc2ccccc12 +Cn1cc(C2CCCN2C(=O)c2cc3cc(Cl)ccc3o2)cn1 +CCCOc1ccc(N2CCN(C(=O)C3CCCCC3)CC2)nn1 +O=C1CCC2(CCN(C(=O)c3ccc[nH]3)CC2)CN1CC1CCCO1 +CCOC(=O)c1c(C)[nH]c(C(=O)N2CCC(C(C)O)CC2)c1C +COc1ccc(CNC(=O)c2ccc(S(C)(=O)=O)cc2)cc1OC +COC(=O)CSc1nnc(-c2ccco2)n1CC1CCCO1 +O=C(NCCCN1CCCC1=O)NC1CCCc2occc21 +C#CCOCC1CCCN(C(=O)c2cc(Cl)cc(Cl)c2)C1 +Cn1cc(C(=O)NCc2ccc3c(c2)CCC3)c(C(C)(C)C)n1 +O=C(C1COCCO1)N(C1CCCC1)C1CCCC1 +COc1cc(N)c(Cl)cc1C(=O)OC(C)C(N)=O +Cn1ccnc1C(NC(=O)NC1CCCCNC1=O)c1ccccc1 +Cc1ccc(-c2nc(CCN(C)C(=O)c3cccs3)no2)cc1 +CNC(=O)c1ccc(=O)n(Cc2cccc(Cl)c2)c1 +Cc1ccc(N2CCC3(C2)C(=O)NCC3COc2ccccn2)nn1 +CC(Cn1nc2c(cc1=O)CCCC2)NC(=O)Cc1cccc(F)c1 +CCOC(=O)CCC(C)NC(=O)C1CCCCCC1 +CCCOC(=O)C1=C(C)N(C)C(=O)NC1c1cccc(O)c1 +CCCN1C(=O)c2ccc(Cl)cc2NC1C1CC1 +COc1cc(-c2conc2N)cc(OC)c1OC +CC(C)C(NC(=O)c1cccs1)C(=O)NC(C)C1CC1 +COc1ccc(C(=O)N(C)Cc2ccc(C)o2)c(Br)c1 +CC(=O)C(NC(=O)CN1CCCc2ccccc21)C(C)C +CCOc1ccc(-c2c[nH]c(-c3cccn3-c3ncccn3)n2)cc1 +CSc1nc2n(n1)CC(C(=O)Nc1ccccc1Cl)=C(C)N2 +CC(=O)C1CN(CCC(=O)Nc2nc(C)cs2)c2ccccc21 +CC1CN(c2ncnc3sc4c(c23)CCC4)CC(C)O1 +CC(C)C(C)NC(=O)c1c[nH]nc1-c1ccc(Cl)cc1 +COc1ccccc1CNC(=O)Nc1ccc(N2CCCC2=O)cc1 +CCc1n[nH]c(=O)c(CNC(=O)Cc2cccc(F)c2)c1CC +CCCCN(CC)C(=O)c1onc(-c2ccccn2)c1N +CCC(COc1ccccc1)NC(=O)NC1CCC(CO)CC1 +O=C(CSc1nc(C=Cc2ccccc2)n[nH]1)Nc1nccs1 +COc1cccc(C(=O)NCc2cc(=O)oc3c(C)cc(C)cc23)c1 +Cc1ccc(C(=O)NC2CCN(C(=O)c3cnccn3)CC2)c(C)c1 +CCOc1cc(CNc2ccc(COC)cc2)ccc1O +CNC(=O)NCC(=O)N1CCCC1C1CCCCC1 +N#Cc1ccc(OCC(=O)N(Cc2ccccn2)C2CC2)cc1 +C#CCNC(=O)c1c[nH]nc1-c1ccc(OC)cc1 +Cn1c(C2CC2)nc2cc(NC(=O)CNC(=O)C3CCCC3)ccc21 +CCOc1cc(S(=O)(=O)n2ccnc2C)c(C)cc1C +Cn1nc(-c2n[nH]c(N)c2-c2nc3ccccc3n2C)cc1C(C)(C)C +Cc1ccc(O)c(NS(=O)(=O)c2cccnc2)c1 +CC(CC#N)N1CCN(C(=O)c2ccc(Br)cc2)CC1 +C=CCn1c(N)nnc1SCC(=O)NC1CCOc2ccccc21 +CC(=O)N1CCN(C(=O)c2ccccc2CCc2ccccc2)CC1 +O=C(Cc1c[nH]c2ccccc12)Nc1nnc(-c2ccsc2)o1 +Cc1cccc(C(=O)NCc2ccc(F)cc2)c1C +CCCCn1nccc1NC(=O)c1cnc(C2CCCO2)s1 +Cc1cnc(C(=O)OCc2cc(C#N)ccc2F)cn1 +CC(NS(=O)(=O)Cc1ccccc1Cl)C(=O)N1CCCCC1 +COC(=O)C(O)C(O)c1ccc(Cl)cc1Cl +CCOC(=O)c1[nH]c2ccc(Cl)cc2c1NC(=O)NC(C)C +OCCCSc1nnc(N2CCOCC2)n1-c1cccc(F)c1 +Cc1cccc(OCCNC(=O)c2ccc(C#N)cc2)c1 +CCc1nnc(NC(=O)c2cn(C)c3c(Cl)cccc3c2=O)s1 +CCC(C)N(Cc1ccsc1)C(=O)CCn1nnc2ccccc21 +COCCNC(=O)c1ccc(=O)n(-c2ccccc2)c1 +CC(NC(N)=O)C(=O)Nc1ncc(-c2ccccc2)s1 +C=C(C)CN1CCN(C(=O)COc2ccc(F)cc2)CC1 +O=C(COc1ccc(F)cc1)N1CCN(Cc2ccsc2)CC1 +CC(C)NC(=O)NC1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +COC(=O)Cc1c(C)c2ccc(OCC(N)=O)c(C)c2oc1=O +CN(CC1CC1)C(=O)c1cc(S(=O)(=O)N2CCCC2)cn1C +COCc1noc(-c2cnc(C3CCCO3)s2)n1 +COC(=O)c1cc(C)ccc1NCc1nnc(C(C)(C)C)o1 +CC(C(=O)NC1CC1)S(=O)(=O)c1ccc2ccccc2c1 +Cn1ncc2c(=O)n(CC(=O)NCC(C)(O)c3ccsc3)cnc21 +CC(=O)Nc1ccc2c(c1)CC(C(=O)NCc1ccccc1F)CO2 +COC(=O)c1cccc(Cc2cnc(NC(C)=O)s2)c1 +Cc1ccc(NC(=O)c2ccc(N3CCCC3)nn2)c2cccnc12 +CC1CCCCN1S(=O)(=O)c1cc(N)cc(Cl)c1F +CC(C)NC(=O)c1ccn(COc2cccc(C(F)(F)F)c2)n1 +CC(C)c1nccc(-c2nccn2CCc2cnc[nH]2)n1 +N#Cc1c(-c2ccccc2)nc(N2CCOCC2)c(C#N)c1N +CC(O)(CNC(=O)C1(C#N)CCCCC1)c1ccc(F)cc1 +Cc1nc(-c2ccncc2)sc1C(=O)Nc1ccc2[nH]ccc2c1 +CCOc1ccc(C(=O)Nc2ncccn2)c(OCC)c1 +O=C(NCCN1CCOCC1)NCc1ccoc1 +Cc1cc(CNC(=O)c2c(C)nn(-c3ccccc3)c2C)ccc1F +O=C(NCC1COCCO1)c1ccc2nc(C3CC3)oc2c1 +CCCCn1c2c(c(=O)[nH]c1=O)C(c1ccccc1Cl)NC(=O)N2 +CCN(Cc1ccccc1)C(=O)COC(=O)c1cccc(O)c1 +O=C(Nc1nnc(-c2ccncc2)o1)c1ccccc1Cl +COC(=O)C1CCCN1C(=O)c1nccc2c(N)cccc12 +CNC(=O)CCc1cc(C2CCCN2S(C)(=O)=O)nc(C)n1 +O=C(c1cn(-c2ccccc2)nn1)N1CCC(O)(C(F)(F)F)CC1 +Fc1cc2c(c(C(F)(F)F)c1)C(c1cc[nH]c1)NCC2 +CCn1nc(C)cc1C(=O)NCC(C)c1cccs1 +CCc1cc(C(=O)N(C)CC(=O)Nc2c(C)cccc2C)sc1C +CCN(CC)C(=O)CN(C)S(=O)(=O)c1ccc(OC)c(C)c1 +COC(=O)c1ccc(C(C)N2CC3OCCN(C)C3C2)o1 +O=C(Nc1ccccc1Sc1ccccc1)C1CCCO1 +O=C(Cc1cn2ccccc2n1)N1CCCC1c1noc(C2CC2)n1 +Cc1ccnc(NC(=O)c2cccnc2OCC(F)F)c1 +CCC1(C(=O)Nc2ccc(F)c(N)c2)CCCC1 +Cc1ccccc1NC(=O)C(C#N)Cc1ccc2c(c1)OCO2 +O=S(=O)(NCc1nnnn1-c1ccccc1)c1ccc(Cl)cc1 +Cc1cccc(C)c1NC(=O)c1cc(=O)c2cccc(C)c2o1 +CCOC(=O)CCN(C)c1nccn(C2CC2)c1=O +CC1CCCCC1NC(=O)c1cc(N)ccc1Cl +O=C(NCc1ccc(Br)cc1Cl)c1cnn[nH]1 +Cc1cc(C)c(C(=O)N(C)CCOc2ccc(F)cc2)c(=O)[nH]1 +CC(C1CCN(C(=O)c2cnn3c2CCCC3)CC1)N1CCOCC1 +NC(=O)c1c(NC(=O)Nc2ccccc2)sc2c1CCCC2 +Cc1nccn1Cc1ccc(NC(=O)NCc2ccn(C)c2)cc1 +O=C(CNc1ccc(C(=O)NCc2ccccc2F)cc1)NC1CC1 +N#Cc1cccc(NC(=O)COc2cccc(Br)c2)c1 +CCN(CCC(=O)OC)C(=O)c1snnc1C +CCc1nc(-c2ccccc2F)nc(N2CCC(=O)CC2)c1C +Cc1ccc(CSc2nc(=O)n(CCCO)c3c2CCC3)cc1 +Cc1nc2ccccc2n1CC1CCN(C(=O)c2cccs2)CC1 +Cn1c(COC(=O)c2ncn(-c3ccccc3)n2)nnc1C1CC1 +Cc1ccc(CCCC(=O)NCC(O)c2c(F)cccc2F)cc1 +Cn1ccc(-c2cc(C(=O)NC3CCCC3)c3ccccn23)n1 +CCNc1ncc(C(=O)N2CCNC(=O)C2Cc2ccccc2)cn1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)NC2CCC(C)CC2)c1 +CCOC(=O)c1c(NC(=O)C#Cc2ccccc2)sc(C)c1C +C=CCCC(=O)NC(C(N)=O)c1ccc(F)cc1 +CC(C)c1ccsc1C(=O)NCCNc1cnccn1 +Cc1csc(SCC(=O)N2CC(C)OC(C)C2)n1 +COC(=O)C1(c2ccccc2)CCN(Cc2ccccc2)C1 +O=C(Cc1c[nH]c2ccccc12)N1CCC(Nc2cccnn2)CC1 +CC(C)c1ccc2c(c1)C(N)C(CN1CCOCC1)CO2 +C=CCN(CC=C)C(=O)c1cc(F)ccc1Br +CN(Cc1ccsc1)C(=O)c1cc(O)nc2ccccc12 +CC(c1ccccc1Cl)N(C)C(=O)NCc1nnc2ccccn12 +CCOc1cc(C2NC(=O)N(C)C(C(C)C)=C2C(=O)OC)ccc1O +CCS(=O)(=O)N1CCc2c(cccc2NC(=O)c2cn[nH]n2)C1 +CN1CC(C(=O)NCc2ccc(OC3CCCC3)nc2)CC1=O +Cc1nn(C)cc1CN1CCCN(c2cccnn2)CC1 +N#Cc1cc2c(nc1SCc1nc(N)nc(N)n1)CCCC2 +COc1cc(C(C)NC(=O)N(C)CC(F)F)ccc1OC(C)C +O=c1c(=Cc2cccc(Oc3ccccc3)c2)sc2ncnn12 +COc1ccc2nc(C)cc(C(=O)OC3C(=O)OCC3(C)C)c2c1 +CC(C)(C)OC(=O)Nc1ccc2ncsc2c1 +COc1ccccc1CN(Cc1cccnc1)C(=O)c1occc1C +CC1CCN(C(=O)NCc2ccc(-n3ccnc3)c(F)c2)CC1 +COc1ccc(NC(=O)C2CC(=O)Nc3ncnn32)c(OC)c1 +Cc1cc[nH]c(=O)c1NCc1cc2cc3c(cc2[nH]c1=O)OCO3 +Cc1noc(C)c1CC(=O)N1CCCCC1c1cc[nH]n1 +Cc1ccc(-c2cnn(C)c(=O)c2CC#N)cc1C +NC(=O)c1c(NC(=O)c2cc(F)cc(F)c2)sc2c1CCCC2 +Cc1nc(C)c(C2NCCc3ccc(F)c(F)c32)s1 +CC1Oc2ccc(C(=O)Cc3nonc3N)cc2NC1=O +Cc1cnn(CCCN2C(=O)OCC2C(C)C)c1 +Cc1nc(-c2cccc(NC(=O)c3cn4c(C)cccc4n3)c2)oc1C +CCS(=O)(=O)c1ccc(NC(=O)c2ccc(OC)cc2OC)cc1 +Cc1ccc(-n2ccnc2)c(C(=O)N(C)Cc2ccccc2C)c1 +CC(Sc1nnc(C(C)(C)C)n1N)C(=O)NCC(F)(F)F +Cc1csc(=O)n1CCC(=O)N1CCCC(c2nncn2C)C1 +CCn1c(SCC(=O)NCc2ccco2)nc2ncccc2c1=O +CCc1ncnc2c1CCN(C(=O)c1sccc1C)CC2 +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)NCc1ccncc1)O2 +C=CCN(CC=C)C(=O)C1CCN(C(=O)c2ccccc2Cl)CC1 +Cc1cccc(Cl)c1OCCNC(=O)C1CNC(=O)C1 +CC(CCCO)NC(=O)NC(C)c1c(F)cccc1Cl +COc1cc(CNc2cccc(NC(C)=O)c2)cc(Cl)c1OC +CC(C)(C)n1c(=NC(=O)c2cccnc2)[nH]c2ccccc21 +CCOC(=O)c1ccn(-c2ccc(NC(=O)COC)cc2)n1 +N#Cc1ccc(C(=O)N2CCC(NC(=O)C3CCCCC3)CC2)cc1 +COCC(C)NC(=O)CSc1ccccc1F +Cc1ccc(C(CNC(=O)Nc2ccc(F)cc2)N2CCOCC2)o1 +Cc1cc(-c2nnc(NC(=O)CC(C)(C)C)o2)c(C)o1 +O=C(NC1CCCC1)c1ccc2ncnc(N3CCCC3)c2c1 +CCNC(=O)c1cc(S(=O)(=O)N(C)Cc2ccccc2)cs1 +COc1ccc(S(=O)(=O)NC2CCCCCC2)cc1C(N)=O +CCn1cnnc1CNC(=O)CCc1ncc(-c2ccccc2)o1 +Cc1cc(C)n2nc(SCc3ccccc3C)nc2n1 +Cc1ccc(S(=O)(=O)NCc2cc(=O)[nH]c3ccccc23)cc1C +Cc1ccc2c(c1)C(NC(=O)CCn1cccn1)C(C)C2 +CC(=O)N1CCC(CCC(=O)Nc2cccc(-c3cn[nH]c3)c2)CC1 +Cc1nnc2sc(SCc3ccccc3Cl)nn2c1=O +COc1ccccc1-n1nnnc1SCCOC(C)C +CC(C)c1cc(C(=O)NCCCN2CCOCC2)nc(N(C)C)n1 +COc1ccc(Cl)cc1C(=O)Nc1cccc(-n2cnnn2)c1 +O=C(Nc1nc(-c2cccnc2)cs1)c1c[nH]c2ccccc2c1=O +CCOc1cccc(C(=O)NCc2cccnc2)c1 +CC(=O)NCC(=O)N(Cc1ccc(C#N)cc1)Cc1cccc(F)c1 +CC(=O)c1ccc(NC(=O)c2cc3c([nH]c2=O)CCCC3)cc1 +CCC(C)Oc1cccc(NC(=O)NC(C)COC)c1 +Cc1nc(NC2CC2)cc(-c2ccc3c(c2)NC(=O)CO3)n1 +CCCS(=O)(=O)N1CCC(C(N)=O)c2ccccc21 +CCC(CC)C(O)CNC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +O=C(COC(=O)C1CCOCC1)NC1CCCc2ccccc21 +Cc1c(N)ccc2nnc(-c3ccc(Cl)cc3)n12 +CC(O)CNC(=O)c1cc2c(s1)-c1ccccc1CC2 +Cc1nc2c(NCCC3CCCCN3S(C)(=O)=O)ncnc2o1 +CCN1CCN(C(=O)c2cn(-c3ccc(C)c(C)c3)nn2)CC1 +c1cncc(-c2nc(-c3ccncc3)ncc2-c2cnccn2)c1 +CC(C1Cc2ccccc2O1)N(C)C(=O)C(O)c1ccccc1 +CCOC(=O)c1ccc(NC(=O)C2Oc3ccccc3OC2C)cc1 +CC(C)(C)n1cc(-c2cnc3ccccc3n2)cn1 +COc1ccccc1CCNC(=O)c1ccn(-c2ccccc2)n1 +CCN(CC(=O)N(C)C)C(=O)c1ccccc1S(=O)(=O)C(C)C +CN(Cc1ccccc1Br)C(=O)C1CCOC1 +Clc1ccc2c(NCc3ccc4c(c3)OCCO4)ncnc2c1 +CCCCOC(C)C(=O)Nc1cc(S(N)(=O)=O)cc(C)c1C +CC(=O)N1CCCc2cc(S(=O)(=O)NCCC#N)ccc21 +O=C(Cc1noc(-c2cccnc2)n1)Nc1ccccc1Cl +CC1(CCNC(=O)Nc2cccc(Cl)c2Cl)OCCO1 +CCc1ccsc1C(=O)NCc1cn(-c2ccc(OC)cc2)nn1 +CCOC1COC2(CCN(C(=O)c3ncccn3)CC2)C1 +O=C(Cc1c2cccccc-2[nH]c1=O)NCc1c(F)cccc1Cl +O=C(CC1CC2CCC1C2)NCc1nnc2ccccn12 +Nc1ccc(OCc2ccncc2)c(Cl)c1Cl +Nc1ccc2c(c1)CN(C(=O)c1ccc3c(c1)OCO3)CC2 +CCC(C)Nc1nc(-c2ccc(C)n(C(C)C)c2=O)cs1 +COCCNS(=O)(=O)c1ccc(C)c(C(=O)NC(C)C)c1 +COCc1cc(=O)c(O)c(C(CC(=O)OC)c2ccc(F)cc2)o1 +Cc1cc(N(C)CC2CCCCO2)n2nc(C)c(C)c2n1 +COC(=O)C1CCN(C(=O)C2C3CCCCC32)c2ccccc21 +CC(NC(=O)c1cc2occc2n1C)c1ccccc1 +CS(=O)(=O)Nc1ccsc1C(=O)NCCCC(N)=O +CCCC(C)NC(=O)NC1CCCc2c1cnn2C +CC(CO)NC(=O)c1cnn(Cc2ccccc2Cl)c1 +COCCn1cnc2c([nH]c3cc(OC)ccc32)c1=O +CC(=O)Nc1cccc(C(=O)Nc2cc(C(F)(F)F)ccc2O)c1 +O=C(c1cccs1)N1CC(c2nc(-c3ccccc3)no2)C1 +Nc1nnc(CCC(=O)Nc2cc(Cl)ccc2Cl)n1N +CC(CNC(=O)CCn1cnc2ccccc21)N1CCc2ccccc21 +COC(=O)C(C)CN(C)C(=O)c1ccc(-c2ccco2)nc1C +CCC(C)C(=O)NCC(=O)Oc1ccc(C)cc1C +CC(C)CNC(=O)CCc1nc2ccccc2s1 +Cc1ccn2c(=NC(=O)Cn3ccccc3=O)[nH]nc2c1 +O=C1COC2(CCN(c3ncccn3)CC2)CN1Cc1ccccn1 +Cc1ccc(C(=O)N2CCCC2C(N)=O)cc1NC(=O)C1CC1 +CN(Cc1ccco1)C(=O)COC(=O)c1cc(=O)[nH]c2ccccc12 +Cn1c(C2CC(=O)N(Cc3ccco3)C2)nc2ccccc21 +COc1ccccc1NC(=O)NCc1cccs1 +O=C(CO)N1CCN(C(=O)c2cc(Cl)ccc2F)CC1 +CC(CNC(=O)N1CCCC1)c1nc(-c2ccccc2)no1 +CCc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1-c1ccccc1 +N#CCCN(Cc1ccccn1)C(=O)C1COc2ccccc2C1 +Cc1ccc(NC(=O)c2cccc(OCC(F)F)n2)c(N(C)C)n1 +CC(C)NC(=O)CN1CCN(C(=O)c2cc3ccccc3o2)CC1 +Cc1cc(NC(=O)C(C(C)C)N2CCCC2=O)ccc1C(=O)N(C)C +CC1Cc2cc(S(=O)(=O)Nc3ccccc3Cl)ccc2N1 +Cc1cc(C)n(-c2cc(Cl)ccc2-c2cnc(N)nc2)n1 +Cc1ccc(C)c(OCCn2c(=O)oc3ccc(N)cc32)c1 +COc1ccc(-c2c(C)cn(C)c(=O)c2C#N)cc1O +Cc1nn(C)c(C)c1NC(=O)COC(=O)c1ccco1 +CS(=O)(=O)NCCNC(=O)c1cc2ccccc2s1 +CCC(=O)c1ccc2c(c1)N(CC(N)=O)C(=O)C(C(C)C)O2 +COc1ccc(Br)cc1CNC(=O)Cc1ccc[nH]1 +Cc1ccc2c(c1C)NC(=O)CC2c1ccc(F)cc1 +CCOc1cc(F)ccc1NC(=O)NCc1ccc(OC)cc1 +COc1ccnc(NC(=O)c2cc(NC(=O)N(C)C)ccc2Cl)c1 +CC(C)S(=O)(=O)NC1CCN(C(=O)C(C)(C)C)CC1 +N#CCSc1nc2ccccc2c(=O)n1-c1ccccc1 +CCCC1CN(C(=O)CCCc2cccs2)CCO1 +CC(Oc1ccc(Cl)cc1)c1ccnc2ncnn12 +CCc1nnsc1C(=O)NCc1ccccc1CO +CCn1cc(C(=O)N2CCN(C)CC2c2ccccc2)cn1 +N#CCn1nc(C#N)cc1-c1ccc(Cl)c(Cl)c1 +C=CCN(CC=C)C(=O)c1cc(C)nc(N2CCCC2)n1 +Cc1ccc(C(O)C(=O)N(C)c2ccccc2)cc1 +CN(C)S(=O)(=O)c1cccc(C(=O)NCCc2ccccc2)c1 +CCOC(=O)c1ccc(NC(=O)c2ccc(F)c(F)c2F)cn1 +COC1CCCC(OC(=O)Cc2c(C)noc2C)C1 +CCCN(CCC)C(=O)NC(C)c1cn(C)nc1C +CN(C)C(=O)C1CC2C(CCN2Cc2ccoc2)O1 +Cc1cc(SCC(=O)Nc2ccccn2)nc(-c2ccncc2)n1 +CC(=O)c1cccc(NC(=O)CNc2ccc(F)c(C#N)c2)c1 +O=C(c1ccccc1F)N1CCN(Cc2ccc3ccccc3c2)CC1 +COc1ccc(-c2nc(Cn3cnc(C4CCC4)n3)c(C)o2)c(F)c1 +Cc1cccc2c1CCNC2C1CC(=O)N(C(C)(C)C)C1 +CC(C)N1CC(C(=O)Nc2cc(Cl)ccc2F)CC1=O +COc1cc(-c2noc(C3CCCN(S(C)(=O)=O)C3)n2)ccn1 +O=C(Cc1cc2ccccc2[nH]c1=O)N1CCC(Oc2ccccc2)C1 +CC(C)N(Cc1ccc(Cl)c(Cl)c1)C(=O)c1cnccn1 +CC(C)C(=O)c1ccc2oc(-c3ccncc3)nc2c1 +Cc1occc1C(=O)Nc1cc(NC(=O)N(C)CC2CC2)ccc1F +N#Cc1c(NC(=O)COC(=O)c2cccs2)sc2c1CCC2 +CCc1ccc(C(=O)CCC(=O)N2CCCCC2)cc1 +Cc1nc(N)c(Cc2ccc(Cl)cc2Cl)c(N)n1 +O=C(Nc1cccc2cccnc12)C1CCCN(C(=O)NC2CC2)C1 +N#Cc1ccc(C2NCCc3cccc(F)c32)c(F)c1 +Cc1cc(COC(=O)Cn2nc(-c3ccc(F)cc3)oc2=O)on1 +O=C(c1c[nH]nc1C1CCCCC1)N1Cc2ccccc2C1 +O=C(C1CCN(C(=O)C2CC3CCC2O3)CC1)N1CCCCCC1 +COc1ccc(N2CC(n3cncc3-c3cnn(C)c3)CC2=O)cc1 +CCC(=O)N1CCN(Cc2nc(C)cs2)CC1 +C#CCNS(=O)(=O)c1ccc(C(=O)NCC(O)c2ccco2)cc1 +N#CCCN(CCc1ccccc1)Cc1ccco1 +CCOc1ccc(OC(=O)c2ccc(-n3ccnc3)nn2)cc1 +O=c1cccc2n1CC1CC2CN(CC#CCO)C1 +CN(C)C(=O)CN(C)C(=O)c1ccc(C2CCCCC2)cc1 +CCCc1ccc(CC(=O)N2CCC(=O)CC2)cc1 +CCOC(=O)C1CCN(C(=O)C2CCC(=O)N2)CC1 +COC(=O)C1CCCc2c1nc(C(C)(C)C)n2C +CNC(=O)c1sc2nc(CC(=O)c3occc3C)[nH]c(=O)c2c1C +O=C1CCC(NC(=O)CSc2ccc(F)cc2)CN1 +CCc1ccc(CN(C)C(=O)Cn2c(=O)n(C)c3ccccc32)cc1 +Cc1ccc(-c2ccc(=O)n(CCOc3ccc(C#N)cc3)n2)s1 +Cc1nc(=O)[nH]c(C)c1CCC(=O)NCc1nc2c(C)cccc2[nH]1 +CC(c1ccccc1Cl)N(C)C(=O)CCCCNC(N)=O +Cc1ccc(F)cc1NC(=O)N1CCN(CC(=O)NC(C)C)CC1 +Cc1cccc(-c2c3c([nH]c(=O)c2C#N)CCC3)c1 +N#CCc1nc(-c2ccc3ccccc3c2)cs1 +CC(=O)Nc1cccc(OCC#CCNC(=O)CCC2CCCC2)c1 +COc1cc2nc(C3CCC3)n(N)c(=O)c2cc1OC +Cc1cc(C(=O)N2CCC(Oc3ncccn3)CC2)no1 +Fc1ccc(C2CN(Cc3cccnc3)CCO2)cc1Cl +CN(CCc1ccccn1)c1ncc(-c2ccco2)c(-c2ccco2)n1 +COc1cc(C)c(NC(=O)Nc2ccc(F)cc2C#N)cc1OC +CC(C)(C)NC(=O)COc1cccc2c1OC(C)(C)C2 +CC1CCC(C(=O)N2CCOC3(CCCC3)C2)O1 +Cc1cnn(CCC(=O)Nc2ccc(-c3nc(C)n[nH]3)cc2)c1 +Nc1[nH]nc(O)c1Cc1cc(Br)cs1 +CC1CN(CC(O)c2ccccc2)c2ccccc21 +COc1cc(C(=O)OCC(=O)C2=NC=CC2)cc2c1OC(C)C2 +COc1cc(C(=O)N2CCN(Cc3nc(C)no3)CC2)ccc1C +O=C(Nc1cnc(N2CCOCC2)nc1)c1ccc(Cl)cc1 +Cc1cccc(-n2c(SCC(N)=O)nc3ccccc3c2=O)c1 +O=C(CCc1ccccc1O)Nc1ccc(N2CCOCC2)nc1 +CCOc1ccccc1NCCC(=O)c1ccc(C)c(N)c1 +CC(C)c1ccc(C(C)NC(=O)NCCNC(=O)c2ccco2)cc1 +N#Cc1nccnc1N1CCCC(Nc2ccccc2)C1 +CCCc1n[nH]c(C2CN(Cc3nnc(C4CC4)o3)CCO2)n1 +O=C(Nc1cc(-n2cccc2)ccc1F)c1cc(F)cc2[nH]cnc12 +CCCc1nnsc1C1NCCc2c(N)cc(F)cc21 +CCOc1ccc(OCC)c(S(=O)(=O)n2ccnc2C)c1 +C=CCn1cnc2c(oc3nc(C)cc(C)c32)c1=O +CCOc1ccc(C(=O)Nc2ccnn2Cc2ccco2)cc1 +CN(C(=O)c1ccccc1SCC1CCCO1)c1nccs1 +CCN1C(=O)C2(CCCCC2)N(C)c2ccc(C(C)=O)cc21 +O=C(Cc1c(Cl)cccc1Cl)Nn1cnc2ccccc2c1=O +Cc1nc(C2CCCN2C(=O)C2CCC(C)(C)c3ccccc32)no1 +O=C(Cn1nc(-c2cccs2)oc1=O)c1ccc(F)c(F)c1 +CC(C)Cc1nc(CC(=O)NCc2ccccc2)no1 +COc1cc(C(=O)NCC(=O)C(C)(C)C)cc(OC)c1OC +CCC(CC)Nc1ccc(S(N)(=O)=O)cc1N +CCc1cc2c(NC3CCc4nc(C)nn4C3)ncnc2s1 +CCn1c(C)cc(C(=O)COc2ccc(C)cn2)c1C +NC(=O)COC(=O)c1cnc(-c2ccccc2)s1 +CCN(CC(=O)c1c(N)n(C)c(=O)n(C)c1=O)c1ccccc1 +CCN(CC(=O)OC)C(=O)c1cc2ccccc2[nH]1 +COCCc1noc(CN(C)C(=O)c2cc(=O)[nH]c3ccccc23)n1 +COC(=O)CCNc1ccc(Cl)cc1C(F)(F)F +CCC(CC)CN(CC)C(=O)c1cccc2c1OC(C)C(=O)N2 +CN(Cc1ccccc1)C(=O)COc1c[nH]c(CO)cc1=O +Cc1c(C(=O)Nc2ccc(F)cc2)cnc2nc(SCC#N)nn12 +COc1ccc(C(C)C)cc1S(=O)(=O)N1CCOCC1 +CCCC(=O)Nc1ccc(OC(=O)C2CC2C)c(C(C)=O)c1 +O=C(Cc1ccccc1F)NCc1ccc(N2CCCCC2=O)cc1 +CC(C)N(CCO)S(=O)(=O)c1ccccc1Cl +CCNC(=O)C1CCN(C(=O)c2[nH]c(C)c(C(C)=O)c2CC)CC1 +Cn1c(SCc2ccc(F)cc2C#N)nnc1-c1ccco1 +CC(CNC(=O)NC1CCC(O)CC1)CN(C)C(=O)OC(C)(C)C +Cc1nonc1OCCNC(=O)c1ccc(-c2ccccc2Cl)o1 +CCCNC(=O)CNC(=O)C1CC(=O)N(c2cc(F)cc(F)c2)C1 +COc1cc(C)ccc1OC(=O)CCc1nc(-c2cccs2)no1 +CC(C)(NC(=O)c1cccs1)C(=O)N1CCN(CCO)CC1 +CN(Cc1ccccn1)C(=O)Nc1cccc(OCC2CCCO2)c1 +C=CCn1c(N)nnc1SCc1cccc(C(N)=O)c1 +Cn1ccnc(NC(=O)CCc2nncn2-c2ccccc2)c1=O +COc1cc(C)ccc1NC(=O)c1ccc2[nH]cnc2c1 +Cc1cc(C)nc(N2CCCN(C(=O)Cc3cccs3)CC2)n1 +Cc1cccc(N(CCC#N)C(=O)c2sc(C)nc2C)c1 +Cc1noc(C)c1CN(C)C(=O)NCC(=O)NC(C)(C)C +O=S(=O)(c1cccs1)N1CCC2(CC1)CNc1ccccc12 +COc1ccccc1-c1noc(COc2cc(C)ccc2C(N)=O)n1 +Cc1nn(CCC#N)c(C)c1CCC(=O)N(C)Cc1ccsc1 +N#Cc1ccccc1Cn1cnc2cc(Br)cnc21 +COc1ccc(CO)cc1OCc1ccc(C)cc1 +COCc1ccc(C(=O)N2CCN(CC(=O)NC(C)C)CC2)o1 +Cc1ccc(C(C)NC(=O)c2ccc(Cl)cc2)o1 +COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2ccc(F)cc2)c1 +CCCNC(=O)NCc1cccn1Cc1ccccc1 +Cc1ccc(OCCc2nc(C(C)N)cc(=O)[nH]2)cc1 +O=C(Cc1ccc[nH]1)N(Cc1cccnc1)CC1CCCO1 +O=C(CCNc1nc2ccccc2c(=O)[nH]1)NC1CCCCC1 +Cc1nc(-c2nc(C3CCOC3)n(CCc3ccccc3)n2)cs1 +CCOCCNC(=O)Nc1ccc(Oc2cccnc2)nc1 +COc1ccc(S(=O)(=O)Nc2cnc(N(C)C)nc2)cc1 +CC(C)(CNC(=O)CC=Cc1ccccc1F)c1ccncc1 +CCn1c(NCCCO)nc2c1c(=O)[nH]c(=O)n2CC(C)C +CC(C)CCOC(=O)Cn1cnc2c(oc3ccccc32)c1=O +CCn1cc(Cl)c(C(=O)NCCC(O)C(C)(C)C)n1 +O=C(Nc1ccc2nc(C3CC3)sc2c1)NC1CCOCC1 +O=C(c1ccoc1)N1CCCC2(CCN(c3cncnc3)C2=O)C1 +CCCc1nnc(NC(=O)c2ccc(N3CCNC3=O)cc2)s1 +COC(=O)c1ccc2c(c1)CC(CNC(=O)c1cc(F)ccc1F)O2 +O=C1COc2cc(NC(=O)c3ccc(C(F)(F)F)cc3)ccc2N1 +COc1ccccc1NC(=O)c1cc(Cl)ccc1N +CCOCCC(=O)N1CC(NC(=O)C2CC2)C(c2ccc(C)cc2)C1 +Cc1ccc(SCCC(=O)NCc2ccnn2C)cc1 +CCc1ccc(C(C)NC(=O)CSc2cc(C#N)ccn2)cc1 +N#CC(NC(=O)c1ccc2c(c1)OCO2)c1ccccc1 +N#Cc1ccccc1NC(=O)c1cc(Cl)ccn1 +Cc1ncsc1CCN(C)Cc1c[nH]nc1-c1ccc(F)cc1 +O=C(Nc1n[nH]c2c(Cl)cccc12)c1ccc2[nH]cnc2c1 +CCOC(=O)C1C(c2ccoc2)n2ncnc2NC1(O)C(F)(F)F +COCc1ccc(C(=O)N2CCn3nc(C(=O)OC)cc3C2)o1 +CC(O)(CCc1ccccc1)CNC(=O)Nc1ccc2c(c1)OCO2 +CN(C(=O)Cn1nnc2ccccc2c1=O)C1CCCCC1 +CCn1c(C)cc(C(=O)COc2ccc(C#N)c(F)c2)c1C +CCc1ccc(OC)c(S(=O)(=O)NCC2(O)CCOCC2)c1 +Nc1cccc(CC(=O)Nc2ccc(F)c(F)c2)c1 +Cc1cccc2c1C(Cc1ccc(O)cc1)NCC2 +COC(=O)CC(Nc1nc2c(s1)c(C)nn2C)c1ccccc1 +O=C(Nc1c[nH]ccc1=O)c1cc(Cl)ccc1-n1cnnn1 +CC(=O)NC(C(=O)NCCNc1ncnc2sccc12)C(C)C +Cn1cc(CN2CCOC(c3nccs3)C2)c(-c2cccnc2)n1 +CCC(CC)C(=O)NCc1noc(-c2cccs2)n1 +COCc1ccccc1C(=O)Nc1ccc2c(c1)OCC(=O)N2 +O=C(NC1CCc2ccccc21)c1cc(-c2cccs2)[nH]n1 +O=C(NCCCCNC(=O)c1ccco1)c1ccco1 +O=C(c1cnn(C(=O)c2ccncc2)c1)c1ccccc1O +CC(O)CCc1ccc(OCCC(=O)N(C)C)cc1 +O=C(c1ccsc1)N1CCCC1c1ccsc1 +COc1cccc(N2CCN(CC(=O)Nc3cc(C)on3)CC2)c1 +Cc1nn(C(=O)CCC(=O)NC2CCCC2)c2ccccc12 +COc1ccc(C(=O)Nc2cc(OC)ccc2NC(C)=O)c(F)c1 +CC(C)NC(=O)CN(C)C(=O)CCc1ccccc1 +Cc1ccccc1OCc1ccc(C(=O)N(C)Cc2ccnn2C)o1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1cccc2[nH]ccc12 +CCc1cc(OC)c(OC)cc1C(=O)Nc1ccc(F)cc1 +COc1cccc(C(=O)CCCC(=O)N2CCCCCC2)c1 +C#CCN(Cc1ccco1)C(=O)Nc1cccc(Cl)c1 +O=C(NCC1CC=CCC1)NC1CCN(S(=O)(=O)C2CC2)CC1 +COCCCNC(=O)NCC(O)c1ccccc1 +CCc1nc(NC(=O)NCc2ccccc2-n2cccn2)nn1C +COCC(=O)Nc1nc(-c2ccc3c(c2)OCO3)cs1 +COC(=O)c1ccc(-c2c(OC)cccc2OC)o1 +O=C(COc1cccc(C(F)(F)F)c1)Nc1ccc2c(c1)COC2 +N#Cc1ccc(CSc2nnc(NC(=O)c3ccc[nH]3)s2)cc1 +Cc1nc(N)nc(C)c1CC(=O)N1CCC(CO)C(O)C1 +CC(=O)Nc1ccc(F)c(C(=O)OCCCC(C)C)c1 +CCC(C)(C)NC(=O)CSc1nc(C)cc(C)c1C#N +O=C(NCC(=O)N1CCc2ccccc21)c1ccc(Cl)c(Cl)c1 +COC(=O)c1ccc(OC(=O)C2CC=CCC2)cc1 +CC(C)C(NC(=O)Cc1ccc[nH]1)c1ccccc1 +O=S(=O)(c1cccnc1)N1C2CCC1COC2 +CCOCc1ccc(CNC(=O)c2ccc[nH]c2=O)cc1 +CNC(=O)c1cccc(NCc2cc(Br)cs2)c1 +Cc1cnc(NC(=O)Cc2ccc(F)cc2F)s1 +COCCNc1nc(Nc2cccc(Cl)c2)c2cnn(C)c2n1 +CCc1cc(NC(=O)N2CCCN(c3nc(C)ns3)CC2)n(C)n1 +CCCCS(=O)(=O)NCC#Cc1ccccc1F +CC1CCN(C(=O)NCCS(=O)(=O)c2ccccc2)CC1 +Cc1nnc(CSc2nnc(-c3ccoc3C)n2C)o1 +N#Cc1ccc2ncc(CN3CCOC4(CCc5ccccc54)C3)n2c1 +CCN(C(=O)CCc1cccc(F)c1)c1ccc(C)nn1 +[H]N=c1n(CCOc2ccccc2C)c2ccccc2n1CC(C)C +N#Cc1c(-c2ccco2)cc(-c2ccc(F)cc2)nc1N +CNC(=O)c1cccc(NC(=O)CNC(=O)NCc2ccco2)c1C +CC(C)c1noc(CCCC(=O)Nc2ccccc2C(F)(F)F)n1 +O=C(CCCN1CCOC1=O)NC1(c2cccc(Cl)c2)CC1 +N#CCOc1cccc(CC(=O)Nc2ccc(CC#N)cc2)c1 +Cc1cc(C(=O)Nc2ccnn2Cc2ccc(Cl)cc2)no1 +O=S(=O)(NCc1ccccc1)N1CCCCC1 +COC(=O)CCCCNC(=O)c1cc(C)cc(Br)c1O +CCN(CC1CC1)C(=O)C(C)NC(=O)c1ccc(Cl)cc1 +COc1cc(-c2cccc(-c3ccn(Cc4ccncc4)n3)c2)ncn1 +O=S(=O)(NCc1ccc(-n2cccn2)cc1)c1ccccc1 +Cc1nc(NCc2ccc(F)cc2)cc(C(=O)N2CCCCC2)n1 +COc1cccc(NC(=O)Nc2sc(C(C)C)cc2C(N)=O)c1 +CC(C)(CNC(=O)C1CCN(C(=O)C2CC2)CC1)c1ccccc1 +COC(=O)c1cccc(NC(=O)CSc2nnc(C3CC3)n2C)c1 +O=C(COc1ccc2ccccc2c1)NCCN1CCCS1(=O)=O +Cn1ncc2cc(C(=O)Nc3ccc(F)cc3)c(N)nc21 +CCc1ccc(CC(=O)Nc2cc(C)nn2C)cc1 +COC(=O)CNC(=O)c1ccc(F)cc1-n1cnnn1 +CN1C(=O)CC(NC(=O)c2ccc[nH]2)C1c1ccc(Cl)cc1 +COC(=O)c1cc(F)ccc1CSc1nnc(CO)n1C1CC1 +Cc1ccnc2nc(C(=O)OC(C)C(=O)N3CCCC3)nn12 +O=C(NCc1cccs1)c1ccnc2c1OCO2 +COc1ccc2cc(-c3cccc(C(C)O)n3)[nH]c2c1 +CSc1ccc(C(=O)Nc2nnc(C3CCCO3)o2)cc1 +COC(=O)c1cc(Cl)ccc1NCc1nc(-c2ccco2)no1 +CCOC(=O)c1[nH]c(C)c(C(=O)OCC(=O)N2CCCCC2)c1C +COc1ccc(N(C(C)C(=O)NC2CC2)S(C)(=O)=O)cc1 +Cc1cc(Cl)ccc1S(=O)(=O)Nc1ccc2oc(=O)[nH]c2c1 +CN(C)C(=O)Cc1ccc(Nc2ncnc3[nH]ncc23)cc1 +CCCc1cc(C(=O)N2CCCC(c3cc(=O)[nH]cn3)C2)n(C)n1 +CC(=O)c1cc(-c2ccccc2)[nH]c1N1CCOCC1 +Cc1nn(C)cc1C(C)NC(=O)N1CCOCC1CC(C)C +Cc1noc(C)c1CNC(=O)Nc1nnc(C2CC2)s1 +Cc1ccccc1CN(C)C(C(=O)NC1CC1)c1ccc(F)cc1 +CCn1c(Cn2cnc(C3CCC3)cc2=O)nc2cc(F)ccc21 +CC(C)Cc1nnc(NC(=O)C(C)n2ccnc2)s1 +CCOC(=O)c1cccc(NC(=O)c2cc(Cl)c[nH]2)c1 +Cc1csc(CNc2ccc(C(=O)NCC(C)C)cc2C)n1 +CC(CNC(=O)NC1CCN(c2ccccc2)CC1)N1CCOCC1 +CC(C)OCc1ccccc1NC(=O)NC1CCc2[nH]ncc2C1 +O=C(Cc1noc(Cc2cccc(Cl)c2)n1)NC1CCCC1 +COc1ccc(C(=O)NC2(c3ccccc3)CC2)c(N)c1 +C#Cc1cccc(NC(=O)Cc2c(CC)noc2CC)c1 +Cc1cccc(OCC(=O)NCCNC(=O)c2ccncc2)c1 +COc1cc(Br)c(CC#N)c(Br)c1 +Cc1cc(C)nc(-n2[nH]c(C)c(CCc3ccccc3)c2=O)n1 +O=C(Cc1ccc(F)cc1)N1CCNC(c2ccccc2)C1 +CC1NCCc2c1sc1nc(-c3ccccn3)nn21 +CC(C)(C)C(=O)N1CCOc2ccc(NC(=O)c3ccncc3)cc21 +O=c1[nH]c(COCc2ccccc2)nc2ccsc12 +COc1ccc(F)c(NC(=O)C(NC(N)=O)C(C)C)c1 +CC(=O)c1ccc(C(=O)NCc2ccnc(C)n2)s1 +Nc1nc2n(n1)CCC(c1ccc3c(c1)CCCC3)C2 +O=C(CCC(=O)N1CCc2sccc2C1)c1ccc2c(c1)CCC2 +CCOc1ccccc1CNC(=O)c1cc(CC)n[nH]1 +CC1CCCC(CNC(=O)C2COc3ccccc3O2)C1 +CCOc1ccc(S(=O)(=O)Nc2ccc(NC(C)=O)cc2)cc1C +Cc1ccccc1CNC(=O)c1nn(C)c(=O)c2ccccc12 +O=C(NCCC1=CCCCC1)c1cc2n(n1)CCCO2 +CCc1onc(C)c1NC(=O)CC(C)c1cccc(OC)c1 +Cc1nc(-c2ccccc2F)sc1C(=O)NCc1ccncc1 +N#Cc1cccc(NC(=O)COc2ccccc2C#N)c1 +CC(C)C(NC(=O)c1cccc(F)c1)C(=O)N1CCNCC1 +Cc1ccc(CNC(=O)C(N)c2ccccc2)s1 +COc1ccc(C2CC(=O)c3c(O)cc(OC)cc3O2)cc1 +CCn1nnnc1-c1cccc(C(=O)NCc2cccc(F)c2)c1 +COCCCNC(=O)C(C)S(=O)(=O)c1ccc(F)c(F)c1 +CNC(=O)Cc1ccc(NC(=O)COc2cccc(C)c2)cc1 +Cc1ccc(-n2nc(C)cc2NC(=O)C(C)c2ccccc2F)nn1 +CCC(CC)N(C)C(=O)COCc1nc(C)no1 +Cc1ccc(C2(Cc3ccccc3C)NC(N)=NC2=O)cc1 +COC(=O)CCC(=O)NC(C)c1cccc(Br)c1 +CCOc1ncc(C(=O)N2CCOCC2C2CC2)cc1Cl +COCCn1nc(C)c(CNC(=O)c2cccc(OC)c2F)c1C +COc1ccc(NC(=O)c2cccc(NC(C)=O)c2)c(Cl)c1 +Nc1c(Nc2ccc(Br)cc2)ncnc1N1CCCC1 +CC(Cc1ccsc1)NC(=O)CN(C)c1ncnc2[nH]cnc12 +Fc1ccc(SCc2noc(C3CC3)n2)cc1 +CC(C(=O)N1CCN(S(C)(=O)=O)CC1)n1ccnc1 +O=C(NC1CC1)c1ccccc1SCc1ccccc1 +O=C(CCNc1ncc(Cl)cn1)NCc1ccccn1 +CC(=O)Nc1cccc(C(=O)NC(C)(C)c2cccc(F)c2)c1 +COC(=O)c1sccc1NC(=O)Cc1cccs1 +COC(=O)C1CC=C(COC(=O)c2[nH]nc3ccccc23)O1 +O=C(c1cc(Cl)ccn1)N1CCc2ccccc21 +CCOc1ccccc1NC(=O)NCc1nnc2ccccn12 +c1ccc(-c2cc(N3CCC4(CCOC4)C3)n3ncnc3n2)cc1 +O=C(c1ccncc1)N1CCCC(CCc2ccccc2F)C1 +O=C(NCCCc1ccc(O)cc1)N1CCOCC1C1CC1 +CC(C)Cc1cc2nnc3c(N)c(N)ccc3n2n1 +Cc1cc(C)n(CCC(=O)Nc2ccc(F)c(N)c2)n1 +O=C(NCc1nc2ccccc2[nH]1)c1ccc(Cn2cccn2)cc1 +Cc1nc(-c2ccc(C(F)(F)F)cc2)sc1C(N)=O +O=C(NC1CCCCC1)NC1CCN(C(=O)C2CC3CCC2C3)CC1 +CCC1CCCCN1C(=O)C12CCC(C)(C(=O)O1)C2(C)C +COc1cccc(CN2CCOC(C)(C)C2)c1OC +Cc1coc2cc3oc(=O)c(CC(=O)NC(C)C)c(C)c3cc12 +CC(=O)N1CCC(n2nc(-c3ccccc3)cc2N)CC1 +Cc1ccc(C(O)CNc2ccc(C#N)cc2)c(C)c1 +CC1CC(C)CN(S(=O)(=O)c2cccc(C#N)c2)C1 +COCC(O)CN(C)C(=O)c1cc(NC(=O)C(C)(C)C)ccc1F +CNC(=O)CSc1nc2ccccc2c(=O)n1-c1ccc(C)cc1 +CCn1nc(C)c2nnn(Cc3cccc4ccccc34)c(=O)c21 +O=C(NCC1(O)CCOCC1)c1cnc2ccccc2n1 +CC(=O)N1CCc2ccc(NC(=O)c3ccc(C)cc3C)cc21 +NC(=O)CCn1nnc2c(cnn2-c2ccccc2)c1=O +Cc1cc(C(=O)NCCCc2ccccc2)c(C)n1C1CC1 +CCc1ccccc1C(=O)Nc1nc(C2CC2)c(C(=O)OC)s1 +CCCc1ccc(Br)c2nnc(C(N)=O)c(N)c12 +CC(NC(=O)N(Cc1ccccc1)CC(F)F)c1cnn(C)c1 +COC(=O)CNC(=O)c1cnn(-c2ccccc2)c1 +CC(=O)c1ccn(S(=O)(=O)c2ccc3c(c2)OCO3)c1 +Cc1occc1C(=O)Nc1cccc(-n2cnnn2)c1 +CC(=O)N1CCC(NC(=O)CNc2ccc(Cl)c(Cl)c2)CC1 +COc1ccc2oc(C)c(C(=O)Nc3nc(CC(N)=O)cs3)c2c1 +COCCS(=O)(=O)N(C)Cc1cccc(Br)c1 +O=C(CCC1CCCO1)NC1(c2ccc(Cl)cc2)CCOCC1 +Cc1ccc(NC(=O)CSc2nc(C)c(C)o2)cc1C +COc1cccc(C(=O)NC2(C#N)CCCCC2)c1 +Cc1cc(C(=O)Nc2cccc(NC(=O)c3cccs3)c2)no1 +O=C(CNC(=O)Nc1cc(F)ccc1N1CCCCC1)NC1CC1 +COc1ccc(-c2n[nH]cc2C(=O)N(C)Cc2ccc(C)cc2)cc1 +CNS(=O)(=O)c1ccc(OC)c(NC(=O)c2ccc(C)cc2)c1 +O=C(Cc1noc(C=Cc2c(F)cccc2F)n1)NC1CCCC1 +CC(=O)c1c[nH]c(C(=O)N(C)Cc2ccc3c(c2)OCO3)c1 +CN(Cc1ncnn1C)C(=O)c1cccc(OCC(F)F)n1 +Cc1ccccc1Oc1ncccc1CNC(=O)c1ccc(C#N)cc1 +Cc1ccc2c(c1)c(CN1CC(=O)N3CCC(O)CC3C1=O)nn2C +CSc1ccccc1NC(=O)c1nc(-c2cnccn2)no1 +CNc1cc(C(=O)NCC(c2ccccc2)c2ccccc2)ccn1 +CC1CN(C)CCN1C(=O)c1cnc2c(c1)c(=O)[nH]c(=O)n2C1CC1 +Cc1nnc(NC(=O)N(Cc2ccco2)CC2CCCO2)s1 +Cc1ccc(CNC(=O)c2sc(-c3ccccn3)nc2C)cc1F +COc1ccc(CCC(=O)Nc2nc(-c3ccco3)cs2)cc1 +COc1ccccc1CNC(=O)C(NC(C)=O)C1CCCC1 +CNc1ccc(C(=O)NC(C)c2cccs2)nn1 +COc1ccc(CNC(=O)c2ccc(Cl)cc2-n2cnnn2)cc1 +CC(C)(C)OC(=O)NCCNC(=O)c1ccc(F)cc1 +CCOc1ccc(CNC(=O)c2cnn(-c3ccc(F)cc3)c2)cc1 +O=C(COCCc1ccccc1)N1CCCCC1Cn1cccn1 +O=C(CSc1ccccc1Cl)NC1CCCNC1=O +CCc1cc(NCC(O)C(F)(F)F)n2ncnc2n1 +CCCSc1nsc(NC(=O)c2cnc3ccccc3n2)n1 +COC(=O)c1ccc(Cn2nnc(C#N)c2-c2cccnc2)cc1 +CC(=O)Nc1ccc(OS(=O)(=O)c2ccc(C#N)cc2)cc1 +Cc1nc(NCC(C)O)c2cc(-c3ccccc3)sc2n1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)CC(C)C +COC(=O)CCCN(C)C(=O)c1cncn1-c1ccccc1 +CCCn1c(=O)n(Cc2cc(-c3ccco3)on2)c2ccccc21 +COc1ccc(-c2cc(C(F)(F)F)n3nc(C)cc3n2)cc1OC +c1ccc2c(c1)CCN(Cc1nc3ccccc3[nH]1)C2 +Cc1ccccc1Nc1ccc(S(=O)(=O)N2CCCC2)cn1 +Cc1cc(Br)cc(C)c1NCC(=O)NC(C)(C)C +C#CCOc1ccc(C(=O)Nc2c(F)cc(C#C)cc2F)cc1 +COc1ccc2nc(CC(=O)c3c[nH]c4ccccc34)[nH]c(=O)c2c1 +CCc1ccc(C(=O)N2CCN(C(C)C(=O)OC)CC2)cc1 +CC(=O)N(Cc1cc2ccccc2[nH]c1=O)c1ccc(C)cc1C +Cc1ccncc1NC(=O)NC1COc2ccccc21 +CCn1ccnc(NCc2scnc2C)c1=O +CCCC(=O)Nc1cccc(NC(=O)c2cnc3ccc(C)cn23)c1 +CCOC(=O)c1sc(NC(=O)c2ccc3[nH]cnc3c2)nc1C +CCN(CC)C(=O)c1cc(Cl)ccc1NC(=O)c1ccco1 +O=C(Cc1nnc(-c2cccc(F)c2)o1)Nc1ccccc1 +CC(C)c1ccccc1NC(=O)CSc1nc(N)cc(N)n1 +CCC(C)n1nccc1NC(=O)COCc1nc(C)no1 +Cc1ccc(CN2CC(C(=O)N3CCC(C)(O)C3)CC2=O)cc1 +CC(C)C(=O)Nc1cccc(NCC(=O)Nc2ccc(F)cc2)c1 +Cc1ccc(S(=O)(=O)N2CCCC(C(=O)NC(C)(C)C)C2)cc1 +Cc1ccccc1Sc1nccnc1SCC(=O)NC(C)C +CC(C)(C)CC(NC(=O)N1CCCC1CO)C(F)(F)F +CC(OCC(F)(F)F)C(=O)Oc1ccc2c(c1)OCO2 +CNC(=O)c1cccc(NC(=O)c2cc(Cl)c[nH]2)c1C +CC(NC(=O)c1cc2ccccn2c1)c1cccc(N2CCOC2=O)c1 +Cc1cc(NC(=O)CCC(=O)N(CCC#N)c2ccccc2)no1 +COc1ccccc1NC(=O)Cc1ccccc1O +COc1ccc(Cl)cc1NC(=O)C1CC(=O)N(C(C)(C)C)C1 +COC(=O)c1cc(CCc2ccc(OC)cc2)nn1C +O=C(Nc1cccc(Cl)c1-n1cncn1)C1CC2C=CC1C2 +Cc1cc(NC(=O)NC(CC(C)C)c2ccccc2)no1 +CC(=O)Nc1cc2c(cc1N1CCCCC1)n(C)c(=O)c(=O)n2C +Cc1ncsc1CN1CCN(c2ncnc3ccsc23)CC1 +Cn1c(SCc2cc(-c3ccc(Cl)cc3)no2)n[nH]c1=O +O=C(NCCc1ccccc1)c1nnc(-c2ccc3c(c2)OCO3)o1 +CC(C)Oc1ccc(C(=O)NCC(O)c2ccoc2)cc1 +Cc1oc(C(=O)Nc2nc[nH]n2)cc1S(=O)(=O)N1CCCC1 +O=C1CN=C(c2ccccc2)c2oc3ccccc3c2N1 +Cc1cccc(NC(=O)c2sc3nc(C)cc(C)c3c2N)n1 +COCC(C)N(C)C1CC2(CCC1N)OCCO2 +CCOc1ccc(F)c(C(=O)NCc2cccnc2)c1F +O=C(c1scnc1C1CC1)N1CCN(C2CCCC2)CC1 +Cc1noc(COc2ccc(NC(=O)c3cnn(C)c3C)cc2)n1 +CCc1ccc(NC(=O)C2CC3CCC2O3)cc1S(N)(=O)=O +c1nc(N2CCCC2c2nnc3n2CCCCC3)c2sccc2n1 +O=C(OCCc1cccnc1)c1csc(-c2cccs2)n1 +COCCCNC(=O)Cn1nnc(-c2ccccc2)n1 +Cc1cccc2cc(C(=O)N3CCC(Oc4cccnc4)CC3)n(C)c12 +CC(C)c1nnnn1CC(=O)Nc1cc(F)cc(F)c1 +O=C(NCc1cccnc1)c1ccc(COc2ccc(F)cc2)o1 +COc1ccc2oc(C(=O)NCc3ccco3)c(C)c2c1 +COc1cccc2sc(NC(=O)c3cccn3C)nc12 +CCC(NC(=O)N(C1CC1)C(C)c1ccco1)c1noc(C)n1 +COc1ccc(Cc2nnc(NC(=O)C(C)C)s2)cc1 +COCCC1(CNC(=O)Nc2cc(C)cc(C)n2)CCC1 +COc1ccc(-c2noc(CSc3nncs3)n2)c(OC)c1 +CC(C)(C)OC(=O)NCc1nc2ncc(Br)cc2[nH]1 +COCc1cccc(C(=O)N2CCCC(c3nc(C)cs3)C2)c1 +Cc1cccc(-c2nsc(SCC(=O)N3CCOCC3)n2)c1 +Cc1ccc(C#N)cc1NC(=O)c1cnn(CC(C)C)c1C1CC1 +N#Cc1ccc(NC(=O)C2Cc3ccccc3C(=O)O2)cc1 +CCn1ncc(NC(=O)C2CCN(S(C)(=O)=O)CC2)c1C +O=S1(=O)CCCCN1CCOc1ccc2c(c1)CCCC2 +CCc1ccccc1NC(=O)c1ccc2c(c1)c(=O)cc(C)n2CC +CCOC(=O)C(C)(C)NC(=O)c1[nH]ncc1Br +CC(C)CN(C(=O)c1ccc(C(F)(F)F)cc1)C1CC1 +CCc1nc(NCC(C)C)c(N)c(OCC(C)C)n1 +c1ccc(-c2csc(CCNCc3ccncc3)n2)cc1 +CC(NC(=O)NCCO)c1cccc(N2CCCC2=O)c1 +CCOCCCNC(=O)N(C)Cc1cccc(F)c1 +CCC(=O)N1CCN(c2cc(-n3ccc(C)n3)ncn2)CC1 +O=C(c1ccncc1)N1CCC2OC(c3nnc(C4CC4)o3)CC2C1 +Cn1cccc1C(=O)OCC(=O)N1CCN(c2ccc(F)cc2)CC1 +CCCn1c(C)cc(C(=O)CSc2ncnc3ccsc23)c1C +CS(=O)(=O)c1ccc(F)c(NCC(=O)Nc2ccc(F)cc2)c1 +O=C(NCCCn1ccnc1)C1CC(=O)N(C2CCCC2)C1 +CCCCNC(=O)Cn1ccc2ccccc2c1=O +CC(C)CN1CCOC(CNC(=O)c2ccc3[nH]nnc3c2)C1 +CN(CCCNC(=O)c1cnns1)c1ccccc1 +Nc1cc(C(=O)N2CCc3c(nc(-c4cccnc4)[nH]c3=O)C2)n[nH]1 +CCc1cccc(C)c1NC(=O)COc1ccc(C(C)=O)cc1 +Cc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +COCCNC(=O)CN(C)c1ccc(Cl)cc1N +O=C(CNC(=O)c1cnc2ccccn2c1=O)NCc1ccco1 +CCN(C(=O)COc1ccc(Br)cc1C(C)=O)C1CC1 +CC(C)CN1CC(c2ncc(-c3cccnc3)[nH]2)CC1=O +COc1ccc2c(c1)CCCN2S(=O)(=O)c1c(C)noc1C +Fc1ccc(-n2nc(C(F)(F)F)c3c2CCNC3)cc1F +Cc1ccccc1-n1ccnc1SC(C)C(=O)NC1CC1 +Cc1cc(C(=O)N2CCCC(NC(N)=O)C2)c(C)s1 +CCCCc1ccc(CC(=O)N2CCCN(C(N)=O)CC2)cc1 +COc1ccccc1NC(=O)Cn1c(-c2ccccc2)nc(C)cc1=O +c1ccc(Cn2ccc(Nc3ncnc4ccccc34)n2)nc1 +Cc1cc(C(=O)NC2CCCN(c3ccccc3F)C2=O)c(C)s1 +COc1ccc(CN(C)C(=O)CNC(=O)c2cccc(C)c2)cc1F +CS(=O)(=O)NCc1cncc2c1CCN(Cc1nccs1)C2 +O=C(CCSc1ccccn1)Nc1cccc(Br)c1 +Nc1ccccc1-c1nnc(NC(=O)c2ccccc2)s1 +OCCOc1ccccc1OCc1ccc(F)c(F)c1 +c1ccc2c(Oc3ccc4c(c3)OCO4)ncnc2c1 +Cc1ccn(Cc2ccc3c(c2)OCCO3)c(=O)c1 +O=C(NCc1ccncc1)NCc1cc(Cl)ccc1OC(F)F +Cc1cccc(C(=O)OCC#Cc2ccccc2)n1 +Cc1ccc(S(=O)(=O)NCC(O)C2CCCCC2)cc1 +CC(C)c1nc2oc(N)cc2n1Cc1ccccc1 +CC(C)NC(=O)c1ccc(OCc2cccs2)cc1 +O=C(c1ccoc1)N1CCc2ccc(=O)n(CC3CC3)c2CC1 +CC(C)Oc1ccc2nc3c(cc2c1)c(N)nn3CCO +N#CCCCn1ccc2cc(OCc3ccccc3)ccc2c1=O +COc1ccc(OC)c(Nc2ccc(S(C)(=O)=O)nn2)c1 +Cc1c(C2CC(O)=Nc3c2c(=O)[nH]n3C2CCCCC2)cnn1C +CCCC1CN(C(=O)Cc2csc(N3CCNC3=O)n2)CCO1 +CC(C)(CNC(=O)NCCOc1ccc(C#N)cc1)c1ccncc1 +Cc1nn(CC(=O)N2CCCc3ccccc32)c(C)c1Br +Cc1cc2c(=O)n(Cc3ccccc3Br)cnc2s1 +COCCC1CCCCN1C(=O)Cn1cccc(C(F)(F)F)c1=O +CCOC(=O)C(O)c1cc(Cl)cc(C(C)=O)c1 +CC1Oc2ccccc2N(CCC(=O)Nc2cccc(F)c2F)C1=O +Cc1ncc(CNC(=O)Nc2ccc(F)c(Cl)c2)s1 +Cc1cc(NC(=O)c2ccc(Br)cc2F)n(C)n1 +Cc1ccc2ncc(C(=O)OCc3nc(C)sc3C)n2c1 +Cc1nc(Cn2c(=O)oc3cccnc32)sc1C +COC(=O)c1nnn(CC(=O)N2CCOCC2)c1N +CCOc1cc(CO)ccc1OCC(=O)NC1CCCCC1 +COc1cccc(C(=O)NCc2cccc(OCc3ccccn3)c2)c1 +CC(C)OCCCNC(=O)Cn1cnc2c([nH]c3ccccc32)c1=O +Cc1cc(=O)c(C2NCCc3ccc(Cl)cc32)c[nH]1 +O=C(COc1ccc(Cl)cc1)NCC1(CO)CC1 +C=CCNC(=O)c1ccccc1NC(=O)c1cccc(OC)c1 +CNC(=O)C1CCCN1S(=O)(=O)N(C)C(C)C +Cn1nccc1CNC(=O)Nc1cccc(Cl)c1-n1cccn1 +CC(CN(C)C(=O)c1[nH]ncc1Br)c1ccccc1 +Cc1ccccc1C(C)NC(=O)NCCOCC(C)C +N#CC(C(=O)C12CC3CC(CC(Cl)(C3)C1)C2)c1ccccn1 +Cc1noc2nc(C3CC3)cc(C(=O)NC3(C)Cc4ccccc4C3)c12 +Nc1ccc2c(cnn2Cc2ccc(C(F)(F)F)cc2)c1 +O=C(Nc1ccc(C(=O)N2CCCC2)cc1)c1cnn2ncccc12 +Cc1nn(C)cc1CN1CCOC(c2nc(C(C)(C)C)cs2)C1 +Cc1ccc(CN(C)C(=O)c2ccc(-n3cnnc3)cc2)o1 +CC(C(=O)Nc1ccc(Cl)cn1)N1CCn2c(nnc2C2CC2)C1 +CCc1nnc(CNc2ccc(Br)cc2C(C)=O)o1 +CN(Cc1ccc(OCc2cccs2)cc1)S(C)(=O)=O +CCCCn1c(C)c(C)c2c1ncn1nc(-c3ccncc3)nc21 +COC1C2CCC1CN(C(=O)Cn1c(=O)c(C)nc3ccccc31)C2 +COc1cccc(CNc2nc3ccccc3n2C)c1OC +CCCn1nnnc1CSc1nnc(C)n1N +CC1CCN(C(=O)CNc2cccc(-c3nnnn3C)c2)CC1 +Cc1ccn2c(=O)nc(SCC(=O)N3CCCCCC3)nc2c1 +COCCC1CCCCN1C(=O)Cc1c[nH]c2ccccc12 +O=C(Nc1cccc(OCc2cccnc2)c1)c1ccc2cncn2c1 +c1ccc(-c2cc(NC3CC3)nc(-c3cccnc3)n2)nc1 +CCCOC(=O)c1ccc(F)c(S(=O)(=O)N2CCCCC2)c1 +CCCc1n[nH]c(SCc2ccc(OCC)cc2)n1 +N#Cc1cnn(C(=O)c2ccc(Cl)cc2)c1C1CC1 +Cc1[nH]ncc1CCCNC(=O)NCC1CN2CCCCC2CO1 +O=S(=O)(NCc1ccnc(OC2CCC2)c1)c1ccccc1F +O=C(NCCC(=O)N1CCCCC1)Nc1cc(F)ccc1F +Cc1ccc(CN(C)C(=O)c2ccc3ccccc3n2)o1 +Cc1c(C(=O)N2CCOCC2C)cnn1-c1cccc(Cl)c1 +Cc1nn(S(=O)(=O)Cc2ccccc2)c(C)c1Cl +O=C(Nc1cccnc1)c1cc(=O)c2cc(Cl)ccc2o1 +CNC(=O)c1cc(NC(=O)NCCCC(C)C)ccc1Cl +CC(=O)c1ccc(NCc2ccc(O)cc2F)cc1 +Cc1ccc(C(=O)N(C)Cc2cnn(-c3ccccc3)c2)s1 +CC(C)C(=O)N1CCN(CCC(=O)Nc2ccccc2C#N)CC1 +CCOC(=O)Cn1nc(-c2ccccc2Br)cc1N +COCC(NC(=O)C1(c2ccc(F)cc2F)CCOCC1)C(N)=O +CC(Sc1ccccn1)C(=O)N(Cc1ccccc1F)C1CC1 +Cc1noc(C)c1CN(C)C(=O)c1ccc(Br)cn1 +CC(C)NC(=O)CN1CCN(C(=O)c2ccc(F)c(F)c2)CC1 +Cc1ccc(CC(=O)OCc2nnc(-c3ccccc3)o2)cn1 +CCOC(=O)CC(C)CNC(=O)c1c(C)nn2cccnc12 +Cc1nnc2n1N=C(Nc1ccc(Cl)cc1)CS2 +Nc1nc(NC2CC2)c2ncn(C3CCC(CO)C3)c2n1 +CCOC(=O)c1n[nH]c2c1CCc1c-2c(C)nn1C +O=c1ccc(-c2nnco2)cn1Cc1cc(Cl)c2c(c1)OCCO2 +O=C(NCc1ccnc(OC2CCC2)c1)NC(CO)c1ccco1 +Cc1n[nH]c(C)c1CNc1cc(C(C)C)nc2ccnn12 +COc1ccc(-c2noc(CNC(=O)OC(C)(C)C)n2)cc1 +CCc1nc(N2CCCCCC2)c2c(n1)c(C)nn2C +Cc1ccccc1-n1ccc2c(c(C)nc3ncnn32)c1=O +COc1ccc(OC)c(-c2nc3c(s2)C(=O)CCC3)c1 +Cc1ccccc1-c1nc(N)n(C(=O)c2cccnc2)n1 +COC(=O)c1ccc(OCc2nnc(-c3ccccc3)o2)cc1 +O=C(Cn1cnc2ccccc2c1=O)NCCc1cccc(O)c1 +CC(=O)c1ccc(C)n(CC(=O)Nc2ccccc2C)c1=O +NC(=O)CN1C(=O)N2CCN=C2c2ccc(Cl)cc21 +O=C1CCC2(CCC(NC(=O)c3ccc4ncccc4c3)CC2)N1 +Cc1nc(C)n(CC2CCCN2Cc2cnc(C)s2)n1 +COc1ccc(CNC(=O)CS(=O)(=O)c2ccc(C)cc2)cc1 +CC(C)c1nc(CCNC(=O)CC2C=CCC2)cs1 +Cc1ccc2c(CNC(=O)Cc3cccs3)cc(=O)oc2c1 +COC(=O)N(C)c1ccc(NC(=O)c2cccs2)cc1 +COc1cccc(C(=O)NC2c3ccccc3CC2O)c1OC +CCCOC(=O)c1ccc(CSc2nncc(=O)n2N)cc1 +CN(C)C(=O)c1ccc(C(=O)OCCOc2ccccc2F)cc1 +CC(NS(=O)(=O)c1ccc(F)c(F)c1)c1cccs1 +CC1CN(Cc2c(O)c(=O)cc(CO)n2CCO)CC(C)O1 +CCOC(=O)c1c(O)c(Br)c2ccccc2c1O +Cc1noc(C)c1C(=O)NCCCc1ccccc1 +CC1(C)C(=O)NCCN1C(=O)c1sc2ccccc2c1Cl +Cc1cccc(N2CCN(C(=O)Cn3nnc4ccccc43)CC2)c1 +COC(=O)c1ccc(COC(=O)c2c[nH]c3ccccc23)o1 +Cc1noc(CN2CCN(S(=O)(=O)c3c(C)noc3C)CC2)n1 +COc1ccc(S(=O)(=O)NC(C)(C)C#N)cc1OC +CC(C)COCCCNC(=O)Nc1ccc(C#N)c(Cl)c1 +CNC(=O)NCc1nnc(C(=O)Nc2ccc(F)cc2)s1 +CC(C)(C)c1ncc2c(n1)CN(C(=O)c1cc3cc(F)ccc3[nH]1)C2 +CCN(CC(F)(F)F)C(=O)Cc1ccccc1Cl +Cc1nc2ccccc2nc1N(C)Cc1cnn(-c2ccccc2)c1 +CCCCC(=O)Nc1c(N)n(C)c(=O)n(CC2CC2)c1=O +Brc1cnc2oc(-c3ccccn3)nc2c1 +Cn1c(=O)n(CC(=O)NC2(C)Cc3ccccc3C2)c2ccccc21 +O=c1[nH]c(CN2CCN(c3ncccc3F)CC2)nc2ccccc12 +O=C(NCc1cn[nH]n1)c1sccc1-c1ccccc1 +CC(C)(C)CC(=O)NCC(=O)Oc1cccc(C(N)=O)c1 +O=C(Nc1ccc2oc(=O)[nH]c2c1)c1cccnc1OCC(F)F +CCc1nc(CNc2cc(OC)ccc2OC(C)C)no1 +COC(=O)c1cc(NC(=O)NCc2ncn(C)n2)c(F)cc1F +CC1=CC(C)(C)Nc2c(C(=O)N3CCCC3)cc(C)cc21 +Cn1c(=O)n2n(c1=O)C1(C)C=CC2C23C=CC21c1ccccc1CC3 +COc1ccc(-c2nnc3sc(-c4csnn4)nn23)cc1OC +COc1ccc(CN(C)C(=O)c2ccc(F)cc2)cc1OC(F)F +Cc1ccc(S(=O)(=O)NC(C)(C)C)cc1C(=O)Nc1ccccc1 +CC(NC(=O)C(C)(C)Oc1ccc2c(c1)CCC2)c1ccncc1 +NC(=O)c1[nH]nc2c1CCOc1c(Br)cccc1-2 +N#CCCN1CCC(OCCCc2ccccc2)C1 +CCn1cnnc1CNC(=O)NCCC1CCCC1 +COc1ccc(C2CCCN2C(=O)COc2ccc(C#N)cc2)cc1 +Nc1sc2ccccc2c(=O)c1C(=O)NCc1ccccc1 +CCN(CC)C(=O)COc1cccc(NC(=O)C(C)(C)C)c1 +COCC(=O)N1CCCCC1c1nc2ccccc2s1 +CC12CC3CC(C)(C1)CC(OCc1nc4c([nH]1)CCCNC4=O)(C3)C2 +COc1ccc(OCCCSc2nccn2C)cc1 +COC(=O)CCNC(=O)C1CNCc2cc(Cl)ccc21 +NC(=O)CN(C(=O)Cc1cnn(-c2ccccc2)n1)C1CCCC1 +Cc1cccc(OCCC(=O)N2CCOC(C(N)=O)C2)c1C +CCN(Cc1cnn(C)c1)C(=O)c1ccc(=O)n(C)n1 +CSc1cccc(N2CC(C(=O)NCC(=O)NC3CC3)CC2=O)c1 +COc1ccc(Br)c2c1OC(C)(C)C2 +Cc1cccc(C(=O)Oc2cccc(N3CCCC3=O)c2)n1 +CCCCN(C)C(=O)c1onc(-c2ccc(C)cc2)c1N +Cc1noc(CNC(=O)C(C)(C)c2ccccc2Cl)n1 +CC(=O)Nc1cc(C(=O)NC2C3CCOC3C2(C)C)ccc1C +Cn1nncc1CN1CCOC(c2ccc(F)c(F)c2)C1 +COCCN1C(=O)COC2CN(C(=O)NCc3ccccc3)CC21 +O=C(CN1CCN(CC(F)F)CC1)Nc1nncs1 +COc1ccc(CN(C)S(=O)(=O)N2CCCCC2)cc1OC +CCC(C)(C#N)NC(=O)c1ccccc1Br +CCCc1ccc(C(O)CCC(=O)NC(C)C)cc1 +CCCN(Cc1ccccc1)C(=O)CNC(=O)c1ccccc1C +Cc1cccc(NC(=O)CSc2nc3c(c(=O)n2C)SCC3)c1 +O=C(NCc1cc(F)cc(F)c1)c1cn[nH]c1-c1cccs1 +CCc1nc2ccccc2n1CC(=O)N1CCC(C)CC1 +CCn1cc(C(=O)NC(C(=O)OC)c2ccc3ccccc3c2)cn1 +CCCOCC(=O)Nc1ccc(C)cc1OCC +O=C(Nc1nc2c(s1)CCC2C(=O)N1CCCC1)c1ccccc1 +COc1ccc2c(ccn2Cc2nc(C(C)(C)OC)no2)c1 +CC(C)C(OCC1CCCO1)C(=O)N1CCCC(c2cn[nH]c2)C1 +COCCNC(=O)c1[nH]c2c(c1C)C(=O)CCC2 +O=C(NCCSc1c[nH]c2ccccc12)c1cccc(F)c1 +CC(C)(C)C(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +C=CCOc1cccc(CN(CC)C(=O)c2ccc(C#N)nc2)c1 +COc1ccccc1CNC(=O)COC(=O)c1cccc2ccccc12 +Cc1occc(=O)c1OCC(=O)NCc1ccco1 +CC(C)C1CNc2cc(S(C)(=O)=O)ccc2O1 +c1ccc(CNc2cc(-n3ccnc3)ncn2)cc1 +O=C(Cc1ccc(F)cc1F)Nc1ccc(N2CCCCC2)cn1 +NS(=O)(=O)CCNC(=O)C1(c2cccc(Br)c2)CC1 +CCOCCCNC(=O)C1(C)Oc2ccccc2NC1=O +Cc1c(-c2ccccc2Br)c(N)nn1C +O=S(=O)(Cc1ccccc1)Nc1ccc(N2CCOCC2)nc1 +CCc1noc(CC)c1CC(=O)Nc1cc(C#N)ccc1O +COCC(NC(=O)c1cnc2ccc(C)cn12)c1ccco1 +COC(=O)Nc1ccc(OC)c(N2CCCC2=O)c1 +COc1ccc(C(NC(=O)C2CCCC2)c2nccn2C)cc1 +Cc1ccc(CNC(=O)c2cnc(-c3ccccc3)nc2C)cc1 +Cc1nn(C)c2sc(C(=O)Nc3cccnc3)cc12 +Cc1ncc(CN2CCOCC2CC(=O)c2cccs2)s1 +O=C(NCc1ccccc1)c1cccc(OCC2CCCO2)c1 +Cc1sc(-c2ccco2)nc1C(=O)Nc1cccc2cnccc12 +CCC1CN(S(=O)(=O)c2ccc(OCCOC)c(C)c2)CCO1 +CC(C)NC(=O)N1CCCC2(CCC(=O)N(Cc3ccccn3)C2)C1 +Nc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)nn1 +Cn1cnc(CNC(=O)NCC23CC4CC(CC(C4)C2)C3)n1 +C=CCN1CC2=C(C1=O)C(c1ccc(Cl)cc1)NC(=O)N2 +O=C(c1ccnc2ncccc12)N1CCc2ccccc2C1 +COc1ccc(NC(C)=O)cc1NC(=O)NC(C)c1ccc(F)cc1 +Cc1cccc(-n2ccnc2SCc2ccc(C(N)=O)cc2)c1 +C=CCN(CC=C)C(=O)C(C)Nc1ccc2[nH]c(=O)[nH]c2c1 +CC(c1ccco1)N(C)C(=O)CCCSc1ccccc1 +O=C(NC1CC2CCC1O2)c1ccc(OCC(F)F)nc1 +Cc1ccc(-n2nnnc2SCC(=O)N2CCCCC2)cc1C +CCN(Cc1nc(-c2ccc(OC)c(OC)c2)no1)C(C)=O +O=C(Cc1cccc(F)c1)N1CCC(Nc2ncnc3c2CCC3)C1 +CCOC1CCN(C(=O)NC(C)c2ccc(OC(F)F)cc2)CC1 +O=C(Cn1nc(-c2ccco2)ccc1=O)Nc1ccccc1Cl +O=C(c1cc(=O)c(OCc2ccccc2)co1)N1CCCC1 +CC(C)c1ccnc(N2CCCN(C(=O)C3CCC3)CC2)n1 +Cc1c(CNC(C)C(C)n2cccn2)c(=O)n(-c2ccccc2)n1C +O=C(Nc1cccc(OC(F)F)c1)c1ccco1 +CC(=O)NCCNC(=O)NCCNC(=O)c1ccc(F)cc1 +O=C(CCc1nc(-c2ccncc2)no1)Nc1cc(F)ccc1Cl +Cc1ccc(-c2ncco2)cc1NC(=O)c1ncccc1OC(C)C +CCn1nc(C)cc1C(=O)N1CCCCC1c1nc(C)cs1 +CC(C)n1c(=O)oc(=O)c2cc(Br)cc(Cl)c21 +COc1ccc(Cl)cc1NC(=O)CSc1nn2cnnc2o1 +CC1(NC(=O)c2cccc3cn[nH]c23)Cc2ccccc2C1 +CCOC(=O)c1cnn(C)c1NS(=O)(=O)c1c(C)n[nH]c1C +O=C(CNC(=O)c1cc2ccccn2n1)Nc1ccc(F)cc1 +CC1CCN(c2ncnc(Oc3ccc4c(c3)OCO4)c2N)CC1 +CC(C)CCNC(=O)C(C)N1CCN(c2ncccn2)CC1 +COCc1c(Cl)cccc1NC(=O)c1ncn(-c2ccccc2)n1 +Cn1ccc(C(=O)Nc2ccc3sccc3c2)n1 +COC(=O)c1ccc(C(=O)Nc2cccc(Oc3ccccc3)c2)cn1 +CCN1CC(C(=O)N(C)CCCOc2ccccc2Cl)CC1=O +O=C(CCC(=O)N1CCN(C(=O)CO)CC1)c1ccccc1 +Nc1nc(C2CC2)ncc1C(=O)NCCC1=CCCCC1 +CC1(NC(=O)NCc2nnc3n2CCCCC3)Cc2ccccc2C1 +NC(=O)c1ccc(NC(=O)c2cc(-c3cccnc3)on2)cc1 +O=C1CCC(C(=O)N2CCc3ccc(Br)cc32)N1 +NC(=O)CNC(=O)c1ccccc1SCc1cscn1 +CCN(CCCNC(=O)c1c(C)n[nH]c1C)S(C)(=O)=O +Cc1ccsc1C(O)CNC(=O)Nc1ccccc1 +CC(=O)Nc1cccc(NC(=O)CCc2ccsc2)c1C +Cc1ccsc1C(=O)NCC(O)c1ccccc1C(F)(F)F +Cc1nc2ncnn2cc1C(=O)Nc1ccccc1Cl +Cn1ncc2c(=O)n(CCC(=O)NC3CCc4ccccc43)cnc21 +Cc1cc(C)n2nc(CC(=O)NCC3(c4ccccc4)CCC3)nc2n1 +CN(c1ccccc1NC(=O)N1CCC(O)C1)C1CCCC1 +CC(C)Oc1ccc(CNC(=O)c2cccs2)cc1 +O=C(c1ccc2c(c1)OCCO2)N1CCCCC1CO +COc1ccnc(NC(=O)c2ccc(OC3CCC3)cc2Cl)c1 +CC(C)N(Cc1cnn(C)c1)C(=O)c1cscn1 +COc1ccc2[nH]cc(C(=O)Nc3ccc(C(C)=O)cc3)c(=O)c2c1 +N#Cc1c(F)cccc1NCc1ccc(OCC(F)(F)F)nc1 +CCOC(=O)c1cnc(-c2ccc(F)cc2)s1 +CCC(OC1CCCC1)C(=O)N1CCCN(C(=O)c2ccoc2)CC1 +Cc1ccccc1CCNC(=O)COc1ccc(-c2nnco2)cc1 +O=c1ccc(S(=O)(=O)NCC2CCCCO2)c[nH]1 +CN(Cc1ccccn1)C(=O)c1cc(F)cc2[nH]cnc12 +Nn1c(N2CCN(c3ccc(F)cc3)CC2)nncc1=O +O=C(NCc1cccc(Cl)c1)c1csc(C(=O)NC2CC2)n1 +Cc1ccc(OCC(=O)Nc2ccc(C)cc2C)nc1 +COc1cc(NC(C)=O)ccc1NC(=O)c1cccc(OC)c1F +COc1ccc(N)cc1CNC(=O)c1cccs1 +CCC(=O)Nc1ccc(S(=O)(=O)NC2CC2)cc1 +Cc1ccc(COc2ccc(Cl)cc2CNn2cnnc2)cc1 +O=C(c1cc2occc2[nH]1)N1CCC(Oc2cccc(Cl)c2)C1 +Cc1cc(F)ccc1N1CCCC(NC(=O)Cc2cnn(C)c2)C1 +CCCc1ccc(S(=O)(=O)NCc2ccco2)cc1 +CC=CC1NCCc2c(OC)cc(OC)c(OC)c21 +Cc1cc(C)c(CNC(=O)Cc2ccc3ccccc3c2)c(=O)[nH]1 +Cc1ccc(-c2noc(CNc3ccccc3C(N)=O)n2)cc1F +CC(C)N1CC(C(=O)NCc2ccc(Cn3cncn3)cc2)CC1=O +C=CCOCC1c2nnn(C)c2CCN1Cc1ccc(C)s1 +O=c1c(Cl)c(N2CCCC2)cnn1Cc1ccccc1 +Nc1cccc(-c2csc(=O)n2Cc2ccccc2F)c1 +CC(OCCCn1c(=O)[nH]c2ccccc2c1=O)c1ccccc1 +Cc1nc(CN(C(=O)Cn2cnnn2)c2ccc(F)cc2)cs1 +Cc1cc(C(=O)NC2CCCc3nc(-c4ccccn4)ncc32)c(C)o1 +CCc1cc2c(c(C(O)c3ccc(OC)cc3)c1)NC(=O)C2 +CCCc1n[nH]c(C2CN(C(=O)C(C)c3ccsc3)CCO2)n1 +Cc1c(C(=O)Nc2cn[nH]c2)oc2c1C(=O)CC(C)(C)C2 +COc1ccc(OC2CCN(C(=O)C3CNCC(=O)N3)CC2)cc1 +Cc1cnn(C2CN(Cc3cccc(C(=O)N(C)C)c3)C2)c1 +Cc1csc(C(C)NC(=O)Nc2ccc(N3CCCC3=O)cc2)n1 +CC1CCCN(S(=O)(=O)N2CCC(N3CCOC(C)C3)CC2)C1 +Nc1ccc2c(c1)N(CC(=O)NC1CCCC1)CCCO2 +CCN(CC)C(=O)c1ccccc1NCc1cccc(C)c1 +CCC(OC)C(=O)Nc1cccnc1-n1ccnc1C +Cc1cc(N)cc(C)c1NC(=O)c1cccc(N)c1 +Cn1c(=O)c2cn(-c3ccccc3O)cc2n(C)c1=O +CCc1ccc(NC(=O)c2cccc(N3CCCC3=O)c2)cc1 +COC(=O)c1sc(NC(=O)CCn2cc(C)cn2)nc1C +Cc1cc(C)c(C)c(S(=O)(=O)NC(C)C2CCCO2)c1C +O=C(Cc1ccc2c(c1)OCCO2)Nc1cc(F)ccc1F +COc1ccc(CNc2nc(C(F)(F)F)nc(C)c2C)cc1 +Cc1cnc(C(=O)N2CCCC(n3nc(C)cc3C)C2)cn1 +Clc1ccc(-c2cnc(-c3ccncc3)o2)cc1 +Cc1csc(N2CCCN(Cc3ccn(C)c3)CC2)n1 +COc1ccc(C(=O)N2CCC(C(F)(F)F)(C(F)(F)F)C2)cc1 +Cc1cc(C(O)C(C)NCc2ccccn2)ccc1F +CNS(=O)(=O)CC(=O)N1CCCc2cc(Br)ccc21 +CCC(C)Nc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccc(F)cc1 +COc1ccc(-c2cnc(NCc3ccccc3)n2C)cc1 +COCCOc1cccc(NC(=O)c2cc(F)cc3[nH]cnc23)c1 +O=C(c1cc(F)c(Cl)cc1Cl)N1CCN(C(=O)C2CC2)CC1 +CCc1ccc(C2COCCN2S(=O)(=O)CC)o1 +CCCCOc1ccc(C(=O)N2CCC(O)CC2)cc1 +O=C(NCc1ccccc1)c1cccc(-n2cnc3cccnc32)c1 +COCCN1CCN(C(=O)c2scnc2C2CC2)CC1=O +CCOCCC1(CNC(=O)c2oc(C)nc2C)CCCC1 +Cc1cc(C(=O)NC(c2ccccc2)C2CC2)no1 +CCOC(=O)N1CCN(C(=O)C(CC)c2ccccc2)CC1 +CCc1nc(CNc2cc(N3CCCS3(=O)=O)ccc2F)n[nH]1 +Cn1cc(CCCOC(=O)c2nccnc2N)cn1 +CN(C(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1)C1CC1 +CCc1onc(C)c1NC(=O)Cc1cccc(OCC#N)c1 +CCn1cc(C(=O)Nc2ccc(C)cc2)c(=O)c2cc(F)ccc21 +CNC(=O)Cc1noc(C(=O)NCc2ccccc2)n1 +COCC(C)(CCO)NC(=O)c1cccc(Cl)c1F +CC(C)c1nc(CNc2cccc(NC(=O)C3CC3)c2)cs1 +COc1ccccc1NC(=O)C1CC(O)=Nc2ncnn21 +Cc1ccnc(NC(=O)C(C)Oc2ccc3c(c2)OCO3)n1 +Cc1cccc(OCCNC(=O)C2Cc3ccccc3C(=O)O2)c1 +O=C(NCc1ccc(-n2cccn2)cc1)N1Cc2ccccc2C1 +COc1ccc(Oc2cc(CNC(=O)c3cccn3C)ccn2)cc1 +O=C(Nc1nnc(C2CC2)s1)c1cccc(C(F)(F)F)c1 +Cn1nc(C2CC2)cc1NC(=O)COc1ccc(Cl)cc1Cl +COc1ccccc1C(=O)Oc1ccc(-n2cncn2)cc1 +CCNC(=O)CSc1ccc(-c2ccncc2)nn1 +N#Cc1cccc(OS(=O)(=O)c2cc(Cl)c(N)c(Cl)c2)c1 +NC(=O)c1cccc(NC(=O)c2cc3ccccc3[nH]2)c1 +CCCCC(=O)NC(C)c1nc(-c2ccc(OC)cc2)no1 +COc1cccc2c1C(c1ccc(OC(C)=O)cc1)NCC2 +Cc1nccn1-c1cc(CNC(=O)Cc2c[nH]c3ccccc23)ccn1 +Cn1cnc(S(=O)(=O)NCC(=O)NCC2CC=CCC2)c1 +C#Cc1cccc(NC(=O)Nc2ccc(CN(C(C)=O)C3CC3)cc2)c1 +CN(C)C(=O)c1ccc(CNS(=O)(=O)N(C)CCC#N)cc1 +CC(C)CCn1nc(C(F)(F)F)cc(C#N)c1=O +COc1ccc(-c2cc(CC(=O)Nc3cccnc3)no2)cc1 +O=S(=O)(CCc1noc(-c2ccccn2)n1)c1ccccc1 +CCS(=O)(=O)Nc1cc(OC)c(Cl)cc1OC +O=C(NCc1ccccn1)N1CCC(Oc2ccccc2)CC1 +C=CCNC(=O)Nc1ccc(NC(=O)C2CC2)cc1 +CCn1cnnc1-c1cccc(Br)c1 +Cc1noc(C(C)Nc2ccc3c(c2)CCC(=O)N3)n1 +Cc1cc(F)cc(NC(=O)NCc2cnn(C)c2C)c1 +O=C1NCC(=O)N2CCN(Cc3ccccc3C(F)(F)F)CC12 +Cc1cc(C2CCCN2C(=O)c2cn(-c3ccc(F)cc3)nn2)on1 +Cc1ccc(S(=O)(=O)Nc2cccc(C)c2C(N)=O)c(C)c1 +Cc1ccc(NC(=O)C2C3CC4OC(=O)C2C4C3)cc1C +CCC(=O)N(C)c1nnc(-c2ccc(F)cc2)s1 +COc1ccc(SC(C)C(=O)N2CCNCC2)c(OC)c1 +Cn1cnc(-c2noc(CCc3ccc(O)cc3)n2)c1 +CCc1noc(CC)c1CNC(=O)C(C)NC(=O)c1ccoc1 +COCCC1(CNC(=O)Nc2nc3ccc(Cl)cn3n2)CC1 +CCOC(=O)Nc1nc(CC(=O)Nc2cccc(Cl)c2)cs1 +COc1ccccc1N(C)CC(=O)N(C)Cc1ccccc1F +O=C1C2c3ccccc3CCN2C(=O)CN1CCc1ccccc1 +COc1ccc(C(C)NS(=O)(=O)c2ccc(F)cc2)cc1OC +COCCOC(=O)Cn1c(N)nc2cc(F)c(F)cc21 +Cc1cccc(C(C)C)c1NC(=O)CCCn1cncn1 +CCOC(=O)N1CCN(C(C#N)C2CCCCC2)CC1 +CC(C)Cn1cc(N2CC(C(=O)N3CCC(O)CC3)CC2=O)cn1 +O=C(NCC(=O)N1CCc2ccccc21)c1ccc(-n2cccc2)cc1 +O=C(NC1CC1)C1CC2CCCCC2N1C(=O)c1ccccc1 +CCNC(=O)C(N)c1ccc(S(C)(=O)=O)cc1 +NC(=O)c1cccc(CN2CCN(C(=O)c3ccc(O)cc3)CC2)c1 +O=C(c1ccc(F)cc1Cl)N1CCN(S(=O)(=O)C2CC2)CC1 +Cc1ccnc2nc(C(=O)NCC3COc4ccccc4O3)nn12 +CC(=O)Nc1ccc(-c2nc(N3CCCC3)sc2C)cc1 +CC(OC(=O)c1ccc(S(=O)(=O)C(F)F)cc1)c1ccccc1 +CC(C)(C)OC(=O)N1CCCC(OCc2cnccn2)C1 +C=CCN(CC=C)C(=O)CNc1c(F)cc(F)cc1F +Cc1ccc(N2CCC3(CC(OCc4cccnc4)CO3)C2)nn1 +O=C(OCCNc1ncccn1)c1sccc1-c1ccccc1 +Cc1ncc(CNS(=O)(=O)c2ccc(N)nc2)s1 +Cc1ccncc1NC(=O)NCC(C)(C)c1ccncc1 +N#CCCCOc1ccc(OCc2ccccc2)cc1 +Cc1ccc(C(=O)NCCS(=O)(=O)c2ccccc2)c(O)c1 +COc1ccc(Cl)cc1NC(=O)COc1cccc(N)c1 +N#Cc1cccc(Cl)c1N1CCN(c2ccc(O)cc2)CC1 +O=C(c1cccc(-c2ccc(O)cc2)c1)N1CCCC1 +Cc1c(N)cccc1-c1nc(C2CCCC2)nn1C +COc1cc2[nH]c3c(=O)n(CCCO)cnc3c2cc1OC +Cc1csc(NC(=O)c2cc3c(s2)CCC3)n1 +Cc1ccccc1C(NC(=O)Cn1ccccc1=O)C(C)C +Cc1ccc2cccc(Nc3ncnc(NC(C)C)c3N)c2n1 +CC(C)c1noc(CCCNC(=O)Cc2c(F)cccc2F)n1 +CC(C)NC(=O)CC1C(=O)NCCN1Cc1cccc(F)c1F +COc1cc(C)nc(N2CCN(C(=O)CC3C=CCC3)CC2)n1 +COc1ccc(CNc2ccc(F)cn2)c(OC)c1 +CCN(C(C)COC)S(=O)(=O)c1ccc(C#N)cc1 +CCOc1ccccc1C(=O)Nc1cnn(CC)c1C(N)=O +CC(C)CC(O)C1CCN(c2nc(CO)cs2)CC1 +CCNC(=O)N(Cc1ccco1)CC1CC=CCC1 +CCn1ccc2nc3ncnn3c(-c3ccccc3Cl)c2c1=O +CC(=O)c1cccc(NC(=O)c2c(C)nn(-c3ccccc3)c2C)c1 +Cc1c(NC(=O)c2cccs2)cccc1S(N)(=O)=O +CCn1c(C)cc(C(=O)Nc2ccc(-n3cncn3)cc2)c1C +O=C(CCSc1nncs1)Nc1ccccc1F +Nc1nonc1NC(=O)CSc1ncc(-c2ccccc2)nn1 +COC(=O)CNC(=O)CNC(=O)c1ccccc1 +CCC(CC(=O)N1CCC(NC(C)=O)CC1)c1ccc(C)cc1 +Cc1cc(C)cc(NC(=O)CC2CN(Cc3ccccc3)CCO2)c1 +COCCN1CC(C(=O)Nc2ccc(CC#N)cc2)CC1=O +O=c1cc(N2CCc3ccccc3C2)nc2ccccn12 +CC(C)(CNC(=O)c1ccccn1)CNC(=O)c1ccccn1 +CCN(CC)C(=O)C(C)Nc1ccc2c(c1)oc(=O)n2C +Cc1c(C(=O)NCCc2cccs2)[nH]c2c1C(=O)CCC2 +O=C(NCCc1ccc2c(c1)OCO2)c1ccc(-n2ccnn2)cc1 +CC(C)N(C)C(=O)CNC(=O)c1ccc(-c2ccccc2)cc1 +O=C1CN(C(=O)NCC2(Cc3ccccc3)CCC2)CCN1 +COc1ccccc1NC(=O)N1c2ccccc2CC1C(N)=O +Cc1nn(-c2cccc(Cl)c2)nc1C(=O)N(C)C(C)C +N#CCCC(C#N)Cn1cnc2c(Br)cccc2c1=O +COCC(=O)NC(C(=O)N1C2CCC1c1ccccc12)C(C)C +CCOc1ccccc1NC(=O)N1CCCC1c1nc(C(C)C)no1 +CS(=O)(=O)c1ncnc(S(C)(=O)=O)c1N +CC(C)(CO)NC(=O)COc1ccccc1C(C)(C)C +COc1ccc(C=C(C)CN2CCOC(c3cnn(C)c3)C2)cc1 +CC1CN(CC(=O)Nc2nccs2)c2ccccc2S1 +CC(C)(C)OC(=O)N1CCC(n2cccn2)c2cc(N)ccc21 +COc1ccc(Cn2cc(C(=O)NCCc3cscn3)nn2)cc1 +Cc1cnc(C(=O)Nc2nnc(C(C)C)s2)c2cccc(N)c12 +COc1cc(NC(=O)c2cnn(C)c2)cc(OC)c1 +CCOC(=O)c1oc2ccccc2c1NC(=O)CC(C)C +Cc1c(C(=O)NC(Cc2ccccc2)c2ccccc2)cnn1C +O=C1CCC(C(=O)OCC(=O)NC23CC4CC(CC(C4)C2)C3)N1 +CCC(C)NS(=O)(=O)c1cc(Cl)ccc1OC +CCc1ccsc1C(=O)NC(COC)C(N)=O +Cn1nnnc1SCc1csc(CCc2ccccc2)n1 +COCCn1cc(NC(=O)NCCc2ccsc2)cn1 +CC(=O)c1nc(C)c(Cc2ccc3c(c2)OCO3)s1 +CC(C)c1cc(CNC(=O)c2cccc3ncccc23)on1 +COCC(O)CNC(=O)Nc1cc(C)ccc1Oc1ccccc1 +O=C(COc1ccccc1NC(=O)N1CCOCC1)N1CCOCC1 +Cn1ncc(C(=O)Nc2ccc(Cl)c(Cl)c2)c1-n1cccc1 +COc1ccc(C(=O)Cn2nnc3ccccc3c2=O)cc1 +CCCN(C)C(=O)Nc1ccc(C(=O)Nc2ccccc2OC)cc1 +c1csc(-c2ccnn3c(C4COCCN4)nnc23)c1 +CCOC(=O)CNC(=O)COc1ccc2c(c1)OCO2 +O=C(NCC1(O)CCc2ccccc21)c1cc2ccccc2oc1=O +COc1ccc(CCC(=O)N2CCCN(C(=O)CC(C)C)CC2)cc1 +Nc1ccc2c(c1)N(C(=O)c1ccccc1O)CC2 +CSc1ncc(C(=O)N(C)C(C)Cc2ccccn2)cn1 +CCCCCn1c(C)ccc(-c2nnc(NCC)s2)c1=O +Cc1c(C(=O)Oc2cccc(S(C)(=O)=O)c2)cnn1C +Cc1cc(C)c(S(=O)(=O)N(C)CCO)cc1C +N#CCc1ccc(NCc2cc(-c3ccccc3)[nH]n2)cc1 +Cn1ncc2c(NCCNC(=O)c3ccco3)ncnc21 +Cc1ccc(CN2CCN(C(=O)c3ccc4occc4c3)CC2=O)cc1 +O=C(NC1CCCC1)N1CCC(c2nnc(-c3ccoc3)o2)CC1 +OCCOCCNc1ccc(C(F)(F)F)cn1 +CCC(O)CN(c1ccccc1)S(=O)(=O)c1cnn(C)c1 +CC(=O)OC12CC3CC(C1)C(OC(C)=O)(OC(C)=O)C(C3)C2 +Cc1ccc(C)c2c1CCNC2CCC(=O)c1ccccc1 +Cc1cc(N2CCOC(C)(C(=O)N3CCOCC3)C2)ncn1 +CCOC(=O)C(C)(NCC1CC1)c1ccccc1F +CC(C(=O)NC1CC1)N1CCN(c2ccc(F)cc2)CC1 +Cc1ccc(C(=O)NC(CO)c2ccccc2)cc1 +Cn1cnc(CNC(=O)NC(c2cccc(Cl)c2)C2CCCC2)n1 +Cc1ccccc1NCC(=O)Nc1nc(C)c(C)s1 +COC(=O)c1ccc2[nH]c(-c3cccc(N)c3)nc2c1 +COCCN1CCN(C(=O)NC(C)CCC(C)(C)C)CC1=O +Cc1ccc(-c2ncco2)cc1NC(=O)CCSc1ccccn1 +O=C(c1c[nH]c2cc(Cl)ccc2c1=O)N1CCCCC1 +Cc1ccc(C(C)NC(=O)CCNc2ncccn2)s1 +O=C(C1CC1C1CC1)N1CCC(OCc2ccc(F)cc2)CC1 +Cc1cc(C)n(CC(=O)N2CC(Oc3c(C)cccc3C)C2)c(=O)n1 +CC(C)c1ncc(Cl)c(C(=O)NCc2nccs2)n1 +CN(CCc1ccccn1)C(=O)c1cccc(N(C)C)c1 +Cc1cccc2c(=O)n(CCOC(=O)Cc3ccccc3)cnc12 +CCOc1ccc(OCC)c2[nH]c(=O)c(=O)[nH]c12 +CC(NC(=O)c1cccs1)C(=O)Nc1ccccc1C(C)C +O=S1(=O)COCCN1Cc1cccc2ccccc12 +COCCCSc1nc(C)c(C)n1CC(C)C +CCOCC(=O)NCc1c(C(=O)OC)sc2cccc(F)c12 +Cc1ccncc1NC(=O)NC1c2ccccc2CC1C +CCOC(=O)CCn1c(C(C)C)ccc(C#N)c1=O +CN(CCC#N)C(=O)COc1ccc(N)cc1F +CNS(=O)(=O)c1ccc(C(=O)N(C)C2CC2)cc1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)cc2)c1C +CCOc1ccc(NC(=O)COC(=O)c2c[nH]c3ccccc23)cc1 +Cc1nnc(NC(=O)C23CC4CC(C)(CC(C)(C4)C2)C3)s1 +CC(=O)NCCNC(=O)CCCc1cc(F)ccc1F +COc1cc(OC)c2c(c1)C(c1ccccn1)NCC2 +Cc1cnc(C(=O)N2CCCc3c(C)ccc(F)c32)cn1 +Cn1cc(C(=O)NCc2cccc(COc3ccccc3)c2)ccc1=O +CN(C)c1cc(C(=O)Nc2cc(Cl)ccc2F)ccn1 +CC(c1cc2ccccc2o1)N(C)C(=O)Cn1ccnc1 +O=C(Nc1ccn(-c2ccccc2)n1)C1CCOC1 +CN(C(=O)OC(C)(C)C)C1CCN(c2ncccc2C#N)CC1 +CC(c1ccc2c(c1)OCCCO2)C(C#N)N1CCOCC1 +CC(C)C(=O)NC1CC(=O)N(Cc2ccccc2C(F)(F)F)C1 +Cc1noc(C)c1CNC(=O)Cn1nc(-c2ccccc2)ccc1=O +CCN(C(=O)NCc1cccc(Cn2ccnc2)c1)C1CCCC1 +Cn1c(C(=O)NCC(=O)N2CCOCC2)cc2occc21 +O=S(=O)(c1ccc2ccccc2c1)N1CCN2CCCC2C1 +COCCCC(=O)NC1CCC(C)(C)c2ccccc21 +CCOc1ccc2nc(SCC(=O)Nc3cc(C)on3)sc2c1 +COC1OC(=O)C2=C1C1(C)CCCC(C)(C)C1CC2O +COCC(NC(=O)c1cccc(-n2cccn2)n1)C(N)=O +COc1cccc(C(=O)NC(C)Cc2ccccc2F)c1O +Cc1ccc(-c2nc3cc(F)c(F)cc3n2CCCC#N)cc1N +O=C(Nc1cccnc1)c1ccc(Oc2nccs2)cc1 +O=C1Cc2cc(-c3csc(NC(=O)C4CC=CCC4)n3)ccc2N1 +O=C(Nc1nnc(CC2CCCCC2)s1)c1scnc1C1CC1 +COC(=O)CNc1cc(C(=O)NCC(F)(F)F)ccc1C +CC(CO)C(C)NC(=O)NCCC(=O)NC1CCCC1 +Cc1cccc2c1C(NC(=O)c1ccccn1)CNC2 +O=C(Nc1ccc2c(c1)COC2)c1ccc(F)c(COCC2CC2)c1 +COC(=O)c1ccc(COC(=O)C23CC4CC(CC(O)(C4)C2)C3)o1 +Nc1nccnc1C(=O)NCC1(Sc2ccccc2)CC1 +CC(NC(=O)c1cc(C#CCO)ccc1F)C1CC1 +COC(=O)c1cc(-c2ccc(F)cc2)nc2c1c(=O)[nH]c(=O)n2C +CCOc1ncccc1CNc1cc(N2CCCC2CO)ncn1 +O=C(CCN1CCc2ccccc2C1)c1ccc(F)c(F)c1 +C#Cc1cccc(NS(=O)(=O)c2cccc(S(N)(=O)=O)c2)c1 +Cc1ccc(CC(=O)Nc2ccc(-c3nncn3C)cc2)s1 +CCOc1ccccc1NC(=O)NCc1cnn2ccccc12 +O=C(Nc1nnc(-c2cccc(F)c2)o1)c1ccco1 +Cc1ccoc1C(=O)N1CCC(C)c2ccccc21 +C=CCn1c(=O)c2ccccc2n2c(SCCOCC)nnc12 +COCCN1CC(C(=O)N(C)C(C)c2ccccc2F)CC1=O +O=C(NCc1ccccn1)C1CCC2C(CCN2c2ccncn2)O1 +CCCC(=O)N1CCC(C(=O)NCc2cc(C(C)C)no2)CC1 +Cc1cc(C)n2nc(CC(=O)NCc3cc(C(C)C)no3)nc2n1 +NC(=O)c1cccc(S(=O)(=O)NCCc2cccc(F)c2)c1 +Cc1ccccc1N(CC(=O)Nc1cccnc1)S(C)(=O)=O +COc1ccccc1-c1noc(CN(C)Cc2cccc(C#N)c2)n1 +O=C1CCC(C(=O)Nc2ccccc2N2CCCC2)N1 +CSc1nnc(CNC2(c3noc(C)n3)CCCCCC2)s1 +Cc1csc(CN(C)C(=O)C2CN(Cc3ccccc3)CCO2)n1 +OC(CCN1CCc2ccccc21)c1ccc2[nH]ncc2c1 +O=C(Cn1c(=O)[nH]c2ccccc21)NCCc1nnc2ccccn12 +CCCC(=O)N1CCCC(C(=O)NC(C)C(N)=O)C1 +CCCOc1ccc(NC(=O)N(C)Cc2cc(C)on2)c(C)c1 +Nc1ccc(C(=O)NCC(=O)NCC(F)(F)F)cc1 +Cc1cccc(CCNC(=O)N2CCN(c3ccnc(C)n3)CC2)c1 +Cn1cc(NC(=O)N2CCN(C(=O)C(C)(C)C)CC2)cn1 +Cc1ccc(NC(=O)CN(C)C(=O)CCc2ccccn2)cc1 +Cn1cc(CN2CCc3ncnc(-c4cncnc4)c3CC2)cn1 +CCC(C)NC(=O)CSc1nnnn1-c1ccccc1 +CC(C)C(=O)Nc1cccc(CNC(=O)C2CCOC2)c1 +O=C(Nc1ccccc1)C1CCCN1C(=O)Nc1ccncc1 +CC1(C)CN(C(=O)C(O)C(O)c2nc3ccccc3s2)C1(C)C +Cc1ccc(OCc2nnc(SCc3ccccn3)o2)cc1 +Cc1ccc(N2CCN(C(=O)CCn3cccn3)CC2=O)cc1 +COC(=O)CCN(C)C(=O)CSc1ccccc1Cl +Cc1cccn2cc(-c3ccc(S(=O)(=O)N4CCCC4)cc3)nc12 +Cc1cccc(NC(=O)Oc2cccc3ccc(C)nc23)c1 +CC(C)(C)c1ccc(NC(=O)Cn2cc(N)ccc2=O)cc1 +COCc1ccccc1C(=O)NCC(C)Oc1ccccc1 +NC(=O)NCc1ccc(NC(=O)C2CCOc3ccccc32)cc1 +CC(C)NC(=O)CNc1cc(Cl)ccc1C#N +Cc1c(Cl)cccc1Nc1ncnc2c1nnn2C +CSc1nc(-c2ccccc2)c(NC(=O)C2CC2)s1 +O=C(CSc1nccc(=O)[nH]1)Nc1nc(-c2ccccc2)cs1 +Cc1nnsc1C(=O)NCc1nn(C)c2c1COCC2 +COC(=O)c1cccc(OC)c1OC(=O)Cc1cccc(F)c1F +O=C1CN(C(=O)c2cccnc2SCc2ccc(F)cc2)CCN1 +Cc1oc(=O)n(Cc2cc(C3CCCCC3)no2)c1C +O=C(NC1CCCC1)N1CCCC(CO)(CC2CC2)C1 +CC(C)(C)C(=O)CSc1nnc2[nH]c3ccccc3n12 +Cc1cc(C(=O)NC(C)c2c(Cl)ccc(F)c2Cl)no1 +CC(C(=O)c1ccc(Br)cc1)N1CCOCC1 +Cc1cnn(CCC(=O)Nc2ccc(C(=O)NC3CCCC3)cc2)c1 +COc1ccc(F)cc1NC(=O)CCn1c(C)c(C)sc1=O +Cc1noc(C2CN(C(=O)COc3ccc(F)cc3)C2)n1 +Cc1ccc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cn1 +Cc1ccc(N2CCn3c2nc2c3c(=O)[nH]c(=O)n2C)c(C)c1 +Cc1cnn(CC(=O)N2CCC(c3cc4ncccc4c(=O)[nH]3)C2)c1 +Oc1ccc(CSc2ccccn2)c2cccnc12 +Cc1ccc(CCc2nnc3ccc(N)cn23)cc1 +O=C(CCc1cc2ccccc2[nH]c1=O)NCc1cccnc1 +Cc1c(C(=O)N(C)Cc2ccc(F)cc2)sc2ncn(C)c(=O)c12 +Cc1ccc(-c2nc(N)c(C#N)c(-c3cccc(OCCO)c3)c2C)o1 +CN(C)C(=O)CN(C)C(=O)c1ccc(OCC(F)F)nc1 +Cc1cc(C)nc(NC(=O)NCC(O)c2ccccc2)c1 +Cc1ccc(CNC(=O)NCCCn2cccn2)cc1F +O=C(NCCN1CCN(C(=O)c2cccs2)CC1)C1CC1 +Cc1cc(C)c(NC(=O)Cn2ccc(C(C)O)n2)c(C)c1 +COc1cc(CNc2cnccc2CO)cc(Br)c1O +CS(=O)(=O)N1CCN(c2ncccc2N)CC1 +Cn1nccc1-c1nn2c(Cc3ccccc3Cl)nnc2s1 +COc1cccc(-c2noc(COC(=O)c3cnccn3)n2)c1 +CCCCc1ccc(-n2nnnc2SC(C)C(=O)N(C)C)cc1 +CN(CCn1cccn1)C(=O)c1cnn2c(-c3ccccc3)ccnc12 +COc1cccc(CC(=O)NC2CCCNC2=O)c1 +Cc1occc1C(=O)Oc1ccc(C#N)cc1Cl +CCC(=O)N(Cc1ccc(C#N)cc1)Cc1cccc(F)c1 +Cc1nc(C2CC3CCN(C(=O)c4occc4C)CC3O2)no1 +C=CCSc1nc2sc3c(c2c(=O)n1N)CCCC3 +Nc1ccc(Cl)c2c1CS(=O)(=O)N2C1CCCC1 +CC(=O)N1CCN(C(=O)c2nc(C)n(-c3ccc(F)cc3)n2)CC1 +N#Cc1cccnc1N1CCOC(c2ccc(Br)cc2)C1 +CC(C)NC(=O)CCN1CCN(C(=O)C(C)(C)C)CC1 +CCn1ccc(=O)c(NC(=O)C2CC2c2ccc(F)c(F)c2)c1 +CCCN(C)C(=O)Nc1ccc2c(c1)NC(=O)CS2 +Cc1ccc(-c2ncco2)cc1NC(=O)Nc1c[nH]c(=O)c(C)c1 +Cc1cc2nc(NC(=O)c3ccno3)sc2cc1C +CCC(C)NC(=O)CSc1ccc(NC(C)=O)cc1 +O=C(NCC(O)c1ccsc1)Nc1c(F)cccc1F +CC(C)c1ccc(S(=O)(=O)N2CCCC(C(N)=O)C2)cc1 +CC(C(=O)NC1CC1)N1CCN(c2ncc(Cl)cc2Cl)CC1 +O=C(Nc1cccc(N2CCCS2(=O)=O)c1)C1CC=CCC1 +CCn1cc(-c2ccc(F)cc2)cc1C(=O)N1CCCC1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)NCC3CCCC(C)C3)ccc21 +Cc1cn2c(CN3CCC4(C3)OCCO4)c(C)nc2s1 +COc1cc(C)ccc1NC(=O)Cc1csc(-c2cccnc2)n1 +COCc1ncn2c1CN(C(=O)Nc1cccc(C)c1)CC2 +O=C1C(Sc2nnnn2CC(F)(F)F)CCN1c1ccccc1 +CCCCCN1C(=O)C(C(C)C)Oc2ccc(N)nc21 +O=C(Nc1cccc(Cl)c1F)c1ccncc1 +CCCOCC1CCN(C(=O)Nc2ncn(C)n2)C1 +CCC(CC)C(=O)NCC(O)(c1ccccc1)C1CC1 +CCOc1ccccc1N1CCN(C(=O)NCc2ccsc2)CC1 +CCCCc1nnc(NCc2cccn2C)s1 +O=C(CSc1n[nH]c(=O)n1CCc1ccccc1)N1CCCC1 +CN1C(=O)CN(S(=O)(=O)c2cccs2)c2ccccc21 +CCNC(=O)C1CC=CCC1c1nc2ccccc2s1 +COc1ccc(CC(C#N)N2CCOCC2)c(OC)c1 +CC1Oc2ccc(C(=O)NC3CCCC3)cc2N(C)C1=O +Cc1cn(CC(=O)N2CCCCC2CCn2cccn2)c(=O)[nH]c1=O +COc1ccccc1NC(=O)C1=C(C)NC(=O)NC1c1cccs1 +COc1ccc(CCC(=O)N(C)Cc2ccccc2C)cc1OC +CCCCNS(=O)(=O)c1cccc(C(N)=O)c1 +Cc1ccc(-n2nnc(-c3nc(-c4cccnc4)no3)c2N)c(C)c1 +COc1cc(NC(=O)CC(C)n2ccc(C)n2)cc(OC)c1 +CS(=O)(=O)NCCc1cc(Cl)cc(Cl)c1 +COC(=O)C(C)n1c(CO)nc2cc(F)ccc21 +Cc1ccc2cc(C(=O)NCC(=O)NC3CC3)[nH]c2c1 +CCCCn1nnnc1COc1ccc(C(N)=O)cc1 +Cc1cc(N(C)CC(N)=O)ccc1Br +CCC(C)Cn1nnc(-c2ccc(C(=O)OC)cc2)n1 +O=S(=O)(c1cccnc1)N(Cc1ccsc1)Cc1ccco1 +Oc1ccc(C2NCCc3c(O)ccc(Cl)c32)cc1 +Cc1ccccc1N1CCN(C(=O)C2(C#N)CCCCC2)CC1 +OCCc1cn[nH]c1-c1cccc(Br)c1 +Cn1cc(C2CCCN2C(=O)c2cc3ccccc3[nH]2)cn1 +O=C(c1ccncc1)N1CCCC(C(=O)N2CCCCC2CCO)C1 +Cc1ccccc1N1CCN(C(=O)c2scnc2C2CC2)CC1 +COc1cc(N)c(C(=O)N2CCCCC2)cc1OC +COCc1nn(Cc2noc(-c3ccsc3)n2)c(=O)o1 +CCS(=O)(=O)NCCCNC(=O)C1CC2CCC1C2 +CNC(=O)C(C)OC(=O)c1ccc(CN2CCCC2=O)cc1 +Cc1c[nH]nc1C1CCN(C(=O)c2cc(C(C)C)no2)C1 +O=C(NC1(c2ccc(Br)cc2)CCC1)c1ccnnc1 +Cc1ncsc1CNS(=O)(=O)c1c(N)cccc1Cl +CCNC(=O)N(CCCN1CCOCC1)Cc1ccncc1 +O=C(c1cc(-c2ccco2)n(-c2ccc(Cl)cc2)n1)N1CCCC1 +CCOC1CC(N(C)C(=O)c2cnn(-c3ccncc3)c2C)C1(C)C +CCOC(=O)CN(C)S(=O)(=O)c1cc(Cl)ccc1C +O=C(CC1COCCN1C(=O)CN1CCOC1=O)Nc1cccnc1 +CC1CN(C(=O)NCc2ccc(OCC(F)(F)F)nc2)CC(C)O1 +COc1ccc(NC(=O)CCNS(=O)(=O)c2ccc(C)cc2)cc1 +Cc1ccc(N2C(=O)c3[nH]nc(C)c3C2c2ccco2)cc1 +O=C(NCCCN1CCCC1=O)c1ccccc1Nc1ccccc1 +CC(C)c1cc(C(=O)NCCCC(N)=O)c2cnn(C(C)C)c2n1 +Cc1cccc(NC(=O)c2sc(-c3ccsc3)nc2C)n1 +Cc1cccc(=O)n1CCC(=O)N1CCCC1c1nc(C(C)C)no1 +Cc1ccc(S(=O)(=O)c2nnn(-c3ccc(F)cc3)c2C)cc1 +O=C1CCC(C(=O)NC2(c3ccc(F)cc3)CC2)N1 +OCCNc1nc2ccccc2n1Cc1ccccc1F +Cc1nnnn1CCc1ncnn1Cc1c(F)cccc1Cl +COC(=O)c1cccn1C1CCN(C(=O)c2cccnc2OC)CC1 +COc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1F +Cn1ncc2c(=O)n(CC(=O)Nc3ccccc3OC(F)F)cnc21 +CCCS(=O)(=O)c1ccccc1C(=O)NC(C)C +C#Cc1ccc(C(=O)NCc2ccc(N3CCCC3=O)cc2)cc1 +O=C(NCCCCNC(=O)C1CCCO1)C1CCCO1 +CC1CCc2sc(C(=O)NCC3CCC3)cc2C1 +CCCNC(=O)Cn1ncc2c(N3CCCCCC3)ncnc21 +CCCn1cc(S(=O)(=O)NC(CC)CC)c(N)n1 +O=C(NC1CCN(CC(F)(F)F)C1)c1cc(Cl)ccc1O +Cc1ccccc1NC(=O)c1cc(=O)c(OCc2ccccc2)co1 +O=S(=O)(Oc1cccc(-n2cnnn2)c1)c1ccc(Cl)cc1 +Cc1cc(C)n2nc(CCCNc3nc4ccccc4o3)c(C#N)c2n1 +COC(=O)c1ccccc1NC(=O)c1cccc(N2CCCC2=O)c1 +CCC(C)n1ncc2c(C(=O)Nc3cccc(C)n3)cc(C)nc21 +O=C1CN(C(=O)CCOc2cccc(Cl)c2Cl)CCN1 +CCn1ncc(CN(C)C(=O)Nc2ccc(Cl)cc2)c1C +O=C(CSc1nc(-c2ccc(F)cc2)cs1)Nc1ccncc1 +CC(C)c1ccc(C2CC2C(=O)N2CCN(C(=O)N(C)C)CC2)cc1 +COc1ccc(C(NC(=O)c2cccc(-n3cncn3)c2)C2CC2)cc1 +COCCN1CCN(Cc2cnn(C)c2C)CC1=O +CN(Cc1ccccc1Br)C(=O)c1ccc(C#N)cc1 +Cc1cc(NC(=O)CN(C)C(=O)Cn2nc(C)c(Cl)c2C)no1 +Cn1cc(C(=O)NCCN2CCOCC2)c2cccnc21 +CCn1c(=O)c(C)nc2cc(C(=O)NCc3ccco3)ccc21 +CCS(=O)(=O)c1ccc(S(=O)(=O)Nc2c[nH]nc2C)cc1 +Cc1n[nH]c(SCCN2CC(C)(c3ccccc3)CCC2=O)n1 +COc1ccccc1NC(=O)c1cc2c(cc1Cl)OCCO2 +O=C(NCCOCC(F)(F)F)Nc1ccc(Cl)cc1F +Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CCCC3)CC2)cc1 +Cc1ccc(CN(C)C(=O)C2CCN(c3ccc(C#N)cn3)CC2)o1 +CCc1onc(C)c1NC(=O)Cn1nc(C)c(Cl)c1C +CCN1CCN(C(=O)Cn2c(=O)c(=O)n(CC)c3ccccc32)CC1 +CC1=Nc2ncnn2C(=O)C1CCC(=O)Nc1ccc(C)cc1Cl +Cc1nc2ccc(C(=O)N3CCCCC3Cn3cccn3)cc2nc1C +CC(Oc1ccc(C#N)cc1)C(=O)Nc1cccc(N)c1 +CCN(Cc1cccc(NCc2nc(C)no2)c1)C(C)=O +COc1cc(NCc2cc3n(n2)CCCN(C(=O)N(C)C)C3)ncn1 +COc1ccccc1N1CCN(C(=O)CCO)CC1 +CC(Cc1ccccn1)NC(=O)c1cc(-c2ccccc2F)no1 +COc1ccc(S(N)(=O)=O)cc1C(=O)OC1CCCCC1=O +Cc1ccc2ncc(CNC(C(N)=O)c3ccc(F)cc3)n2c1 +Cc1cccc(C)c1OCC(=O)Nc1ccc(N)nc1C +CC(=O)c1ccc(NC(=O)COc2cccc(N)c2)cc1 +Cc1ccc(S(=O)(=O)NCc2ccco2)cc1C(=O)N(C)C +CC(=O)N1CCc2ccccc2C1C(=O)NC1CC1 +CC(C)CCNC(=O)CSc1nnc(-c2cccs2)n1N +CC(C)Sc1nnc(-c2ccc(Br)cc2)n1N +CC(NC(=O)CCc1nc(-c2ccco2)no1)C1CCC1 +O=C(c1ccc2[nH]cnc2c1)N1CCN(C(=O)C2CC=CCC2)CC1 +CC(OCc1ccccc1)C(=O)Nc1ccc(Oc2cccnc2)nc1 +CN1CCC(Sc2nnnn2-c2ccc(O)cc2)C1=O +O=C(CCn1cncn1)NCCNC(=O)c1cccnc1 +CCOC(=O)N1CCC(NC(=O)c2c(C)[nH]c3ccccc23)CC1 +Cc1ccc(C(=O)NCC(=O)N(C)Cc2ccccc2C)cc1C +Cc1ccc2nc(C3CCCN(C(=O)Cc4ccon4)C3)[nH]c2c1 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1ccccn1 +COC(=O)c1c(N)n(-c2cccc(OC)c2)c2nc3ccccc3nc12 +CSc1ccc(CNC(=O)COc2ccccc2)cc1 +COc1ncc(C)cc1NC(=O)NCc1cnn(C)c1C +CCOC(=O)N1CCC(NS(=O)(=O)c2cc(F)ccc2C)CC1 +CCn1cc(CN(C)C(=O)C2COc3ccccc3C2)cn1 +Cc1ncsc1C(=O)NC1CCN(c2nc(C3CC3)ns2)CC1 +Cc1ccc(C(=O)N(CC=Cc2ccccc2)CCO)c(F)c1F +Cc1ncsc1CCC(=O)NCc1ccc2c(c1)CC(C)O2 +O=C(Nc1cn[nH]c1)c1sccc1-c1ccccc1 +COc1cc(C)c(C(=O)Nc2ccc(C(C)=O)cc2)cc1OC +CC(C)c1noc(CCNC(=O)C(C(C)C)N2CCCC2=O)n1 +O=C(c1ccccc1O)N1CCN(CCO)CC1 +CCCN(C)C(=O)Nc1ccc(-n2nc(C)cc2C)c(F)c1 +COc1c(O)cc(O)c2c1OC(c1ccccc1O)CC2=O +CC(C)NC(=O)CC1(C(=O)NCc2ccccc2)CCCC1 +[H]N=c1n(C)c2ccccc2n1CCOc1ccc(Cl)cc1Cl +O=C(Nc1cccc(Cl)c1)c1ccc(N2CCOC2=O)cc1 +CCc1nsc(NCC(C2CCOC2)N2CCOCC2)n1 +Cc1ccc2c(c1Br)C(C1CC(=O)C1)NCC2 +CCN(C(=O)c1cn(CC(N)=O)nn1)c1cccc2ccccc12 +CC(C)(C)CC(=O)NCCc1nnc2n1CCCCC2 +COc1ccccc1OCC(=O)NC(C#N)CC(C)C +COc1ccc(CCNC(=O)c2cccnc2)cc1 +CCCCNC(=O)NCc1ccc(N2CCCCC2=O)cc1 +CS(=O)(=O)c1ccc(NCC(=O)N2CCCCC2)cc1 +COc1ccc(-c2c(CO)nnn2-c2ccc(C)cc2)cc1 +O=C(COC(=O)c1cccs1)NCc1ccc(Cl)cc1 +CCOC(=O)c1ccc(NCC2CCCOC2)nc1 +Cc1ccc(S(=O)(=O)N2CCOCC2C)cc1 +CCC(C)C(NC(=O)c1cc(Br)c[nH]1)C(N)=O +Cc1ccc(OCC(=O)NCC(O)Cc2ccccc2)cc1 +Cn1cc(NC(=O)CC2NC(=O)c3ccccc3NC2=O)cn1 +CC(NC(=O)Nc1ccccn1)c1cccc(N2CCCC2)c1 +C=CCOC(=O)N1CCNC(C(=O)OC(C)(C)C)C1 +O=C(NCC1(O)CCc2ccccc21)c1cnccn1 +O=C(CCC1CCCO1)N1CCCC(n2cccn2)C1 +Cc1ccsc1C1N(c2ccccn2)C(=O)C2CCCN21 +CC(C)C(=O)N1CCCC1C(=O)Nc1ccc2c(c1)COC2 +CC(C)CN(C(=O)C1CCN(C(=O)OC(C)(C)C)CC1)C1CC1 +COCCC1CCN(C(=O)CN2C(=O)CSc3ccccc32)CC1 +CC1CCN(C(=O)C2CCN(C(=O)c3ccc(Cl)cc3)CC2)CC1 +CC(NC(=O)Nc1ccc2c(c1)COC2)c1ccccc1 +CCc1nc2cc(NCc3cnc(C)s3)ccc2o1 +CCOC(=O)CC(C)CNC(=O)N1CCC(n2cccn2)CC1 +N#Cc1c(N)nc2c(c1-c1ccncc1)CCCCC2 +CCOc1c(N)cc(C)cc1-c1cc(C(=O)OC)no1 +O=C(NCCC(F)(F)F)NCc1ccccc1CO +COc1ccc2c(ccn2CC(=O)N(C(C)C)C2CCC2)c1 +Cc1cc(C(=O)N(CCC(N)=O)Cc2ccccc2)sc1C +NS(=O)(=O)CCNC(=O)Cc1ccccc1Cl +CC(C)c1csc(CCNC(=O)Nc2ccccc2)n1 +CCOc1ccc(C(=O)Nc2cccc3ccc(C)nc23)cc1 +Cc1ccc(S(=O)(=O)NCCC(O)c2ccccc2)cc1C +Cc1cc(NC(=O)CCc2c(C)n[nH]c2C)c2ccccc2n1 +CCS(=O)(=O)N(C)c1ccc(C(=O)NCc2ccccc2C)cc1 +Cc1cccc2[nH]c(CCC(=O)Nc3ccccc3-n3cncn3)nc12 +CCOC(=O)CSc1nnc(C2Oc3ccccc3OC2C)n1C +CCc1ncc(C(=O)N2CCCC2C(=O)NC2CC2)s1 +COC(=O)C1CCCCCC1NC(=O)c1ccc(C)nc1 +COc1cccc(CNS(=O)(=O)c2ccc(N)cc2)c1OC +Cn1cc(CNC(=O)c2coc(COc3ccc(F)cc3)n2)cn1 +COc1ccc(CN2CCN(C(=O)C(C)n3cncn3)CC2)cc1F +Cc1[nH]cnc1C(=O)NCc1ccc(S(N)(=O)=O)cc1 +COc1ccc(C(O)CNc2ccccc2C#N)cc1F +Cc1cc(C)cc(NC(=O)COC(=O)CNC(=O)C2CCCCC2)c1 +C#CCCN1CCN(C(=O)OCc2ccccc2)CC1 +O=C(NCCc1cccs1)NCc1ccc(-n2ccnc2)nc1 +Nc1ccc(NC(=O)COc2ccc(Cl)cc2)c(Cl)c1 +COc1ccccc1Oc1ccc(NC(=O)c2cccnc2)cc1 +CN(C)c1nc2sc(C(=O)OCc3ccno3)cc2s1 +Cc1ccncc1NC(=O)NCC1(Cc2ccccc2)CCC1 +O=S(=O)(Nc1ccc(F)c(F)c1)c1cccc(F)c1 +COc1ccc(-c2ocnc2C(=O)NCCc2ccccc2)cc1 +CC(NC(=O)NCc1ccnn1C)c1cccc(Cl)c1 +CCN(CC(=O)NC(C)C)C(=O)c1cccc(N)c1 +CC(=O)N1CCCC1c1cccc(NCc2cccnc2)n1 +C=C(C)Cn1nnc(CO)c1-c1ccc(OC)cc1 +COC(C)C(=O)Nc1cccc(NC(=O)C(C)(C)C)c1 +CCOc1ncccc1CNC(=O)CSc1nncs1 +CCc1cc(=O)[nH]c2nnc(SCC(=O)c3ccc(Cl)cc3)n12 +COCCNC(=O)C(C)(C)CS(=O)(=O)N1CCNCC1 +CCOc1c(Cl)cccc1NC(=O)C(CC)OC +CSc1ccc(CC(=O)Nc2onc3c2CCC3)cc1 +C=CCNC(=O)Nc1cnc2c(c1)c(=O)n(C)c(=O)n2C +Cn1cc(NC(=O)N2CCCC2c2cccc(Br)c2)cn1 +CC(C)NC(=O)CCNS(=O)(=O)c1ccc(Cl)cc1 +Cn1c2ccccc2n2c(=O)n(Cc3ccncc3)nc12 +Cc1cc(C)cc(OCCC(=O)OCc2nc(C)no2)c1 +CCOc1ccc(C(CO)Cc2ccncc2)cc1 +CCOc1ccc(F)c(C(=O)Nc2ccc(S(C)=O)cc2)c1F +COc1ccc(-c2cc(=O)c3ccc(NC(C)=O)cc3o2)cc1 +CCOc1ccccc1CC(=O)N1CC2CC(O)C(O)CC2C1 +COCCC1(C(=O)NCc2c(F)c(F)cc(F)c2F)CCC1 +COc1cccc(NC(=O)N2CC3CC(C(=O)NC(C)C)C(C2)O3)c1 +CC(NC(=O)CCc1ccc(C#N)cc1)c1ccc(-n2ccnc2)cc1 +COc1cc2c(cc1OC)CN1C(=O)C(C)NC(=O)C1C2 +Cc1ccc(CNC(=O)c2cc(-c3ccncc3)cn2C)o1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cc(C)n(C2CC2)c1C +CC(Sc1ccccn1)C(=O)Nc1ccc(Cn2cccn2)cc1 +O=C(CNC(=O)OCC(F)(F)F)NCc1ccccc1 +CCOc1ccc2nc(SCC(=O)NCc3ccco3)sc2c1 +CCC(C)NC(=O)C(Sc1nnnn1C1CC1)C(C)C +Cc1cccc(-c2nc(-c3cccnn3)no2)c1O +O=C(Nc1cc(Cl)ccc1N1CCOCC1)c1cccs1 +CCCNC(=O)Nc1ccc(C(=O)OCCC)cc1 +CCCn1nc(C(=O)N2CCCC2C(=O)N(C)C)ccc1=O +C=CCNC(=O)c1ccc(NC(=O)c2ccc(=O)n(CCC)n2)cc1 +CCCC(=O)N1CCCC1C(=O)NCCc1nc(C2CC2)cs1 +Cc1ccccc1SCC(=O)N1CCN2CCNC(=O)C2C1 +Cc1ccc(CN(C(=O)Cn2cnnn2)C2CC2)cc1 +Cc1ccc(CN(C)C(=O)c2ccccc2F)c(C)c1 +Cc1ccc2[nH]c(=O)c(CCC(=O)NCc3cccs3)cc2c1 +O=C(C1CCCC1)N(Cc1ccsc1)Cc1ccccn1 +Cc1ccc(CN(C)C(=O)Cn2c(-c3ccccc3)noc2=O)o1 +O=C1CCC2(CCCN(C(=O)CCCc3cn[nH]c3)C2)CN1CCO +CC(=O)Nc1ccc(S(=O)(=O)n2nc(C)cc2C)cc1 +Cc1ccoc1C(C)NCCc1nnc2ccccn12 +COc1ccc(-n2nnnc2-c2ccc(C)c(N)c2)cc1 +CC(Cc1cccs1)NC(=O)CCc1ccsc1 +CCCCS(=O)(=O)NCC(=O)Nc1ccc(C)cc1Cl +N#CC(NC1CCCC1)c1cc(Br)c2c(c1)OCO2 +Cc1nn(-c2ccccc2)nc1C(=O)NCc1ccccc1 +O=C(NCCNC(=O)c1cnn2c1OCCC2)NCc1ccccc1 +O=C(NC1CCc2ccccc21)c1cc(F)ccc1F +CCOCC1CC2(CCN(C(=O)c3ccccc3F)CC2)CO1 +Cc1csc(CCNC(=O)c2cc3c([nH]c2=O)CC(C)CC3=O)n1 +O=S(=O)(Nc1ccc(F)c(Cl)c1)c1cccc2cccnc12 +O=C(Cn1cnc2ccccc21)Nc1nc2c(s1)C(=O)CCC2 +CCN(C(=O)C1CCN(C(=O)c2ccco2)CC1)c1cccc(C)c1 +COc1cccc(COC(=O)CN(C)C(=O)c2ccccc2)c1 +CC1CCC(N(C)C(=O)CSc2nnnn2C2CC2)CC1 +Cc1ccc(C(=O)NCc2ccccc2Cn2cncn2)cc1 +Cc1ccc2nc(C(=O)NC3CCN(c4cnccn4)CC3)cn2c1 +COc1ccc(CC(C)N(C)S(=O)(=O)c2cnc(C)s2)cc1 +Cc1ccc(CC(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)cc1 +Cc1cc(OC(C)C(=O)NCc2csc(=O)[nH]2)ccc1Cl +CCNC(=O)c1cc(-c2cccc(OCCC(C)C)c2)nc(N)n1 +N#Cc1ccsc1NC(=O)CC1CC2CCC1C2 +CC(=O)Nc1cccc(C(=O)Nc2ccnn2C2CCCCC2)c1 +CC1(C)COC(c2ccccc2Cl)CN1Cc1ccc(CO)o1 +COCCN1CCN(C(=O)C2CCC(=O)CC2C)CC1=O +N#Cc1cccc(CNC(=O)NCC(O)COc2ccc(F)cc2)c1 +COc1ccccc1NC(=O)CSc1nnc2ccc(N)cn12 +COC(=O)CNC(=O)c1ccc(-c2ccc(C)c(C)c2)o1 +NC(=O)c1ccc(Cn2c(=O)oc3cc(Cl)ccc32)cc1 +FC(F)n1ccnc1CNCCc1ccsc1 +COc1cc(C(=O)Nc2cnc3ccccc3c2)ccc1OC(C)C +CCCNc1ncc(-c2nc3ccccc3n2C)cn1 +Cc1cc(NC(=O)NC2CCN(c3ccccc3)C2=O)ccc1F +CC(=O)Nc1ccc(O)c(C(=O)N2CCN(c3nccs3)CC2)c1 +COc1ccc(Cl)cc1NC(=O)CCc1nc(C)no1 +COc1cccc(C(C)NC(=O)C(C)n2cc3c(n2)c(C)nn3C)c1 +COC1(CC(C)C)NC(=O)C(O)(Cc2ccccc2)NC1=O +N#CCCC(C#N)CN1CCCC1c1cccs1 +CCc1nnc(CNc2cc(-c3ccccc3)nc3ccnn23)o1 +CN1C(=O)NC(c2ccccc2)C2=C1CN(c1ccccc1N)C2=O +CC(=O)Nc1cc(NC(=O)C(C)c2ccsc2)ccc1F +COc1ccc(N2Cc3nc(=O)n(C4CCCC4)n3C2=O)cc1 +c1ccc2sc(CSc3nncs3)nc2c1 +Cc1cc(NC(C)c2ncccc2C)nc(-c2cccnc2)n1 +CN(C)C(=O)c1ccc(NC(=O)CNCc2ccccc2)cc1 +CC(C)OCCC(=O)Nc1ccccc1C(=O)N1CCCCC1 +O=C1CN(c2ccc(NC(=O)CCn3cncn3)cn2)CCN1 +O=C(Cc1ccc(F)cc1F)OCCN1CCOC1=O +N#Cc1ccc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)cc1Cl +CNC(=O)CCNS(=O)(=O)c1ccc2c(c1)CCCC2 +CCCS(=O)(=O)NCCOc1ccc2c(c1)CCC(=O)N2 +Cn1cc(CC(=O)NCCc2nc3ccccc3n2C)c2ccccc21 +COc1cc(NC(=O)c2ccc(-n3cccc3)cc2)cc(OC)c1 +CN(Cc1ccccn1)C(=O)c1ccc(N)c(F)c1 +CCn1cc(NCc2cc(C(F)(F)F)n(C)n2)c(C)n1 +CCn1c(SCc2ccccc2)nnc1-c1ccncc1 +Cc1csc(=O)n1CCn1cnc2sccc2c1=O +Cc1cccc(NC(=O)CN2CCN(c3nccs3)CC2)c1C +CN(C)c1noc(C2CCN(C(=O)OC(C)(C)C)CC2)n1 +Cc1ccc2c(c1)CCCN2CCN1CCCC1=O +O=C(Cc1n[nH]c2ccc(F)cc12)NCCOc1ccc(F)cc1 +O=C(Nc1ccnn1Cc1ccc(C(F)(F)F)cc1)C1CC1 +O=C(c1ccc2c(c1)COC2)c1cccc(F)c1F +Nc1cc(F)cc2c(CC(=O)n3cnc4ccccc43)noc12 +COCCc1cc(NC(=O)C2CCC3CCCCC3C2)n(C)n1 +CCOCCC(=O)NCC1CCN(S(C)(=O)=O)CC1 +O=C(CCc1nc(-c2cccnc2)no1)OCC(F)(F)F +CC(=O)Nc1cccc(C(=O)Nc2cccc(CO)c2)c1 +COC(=O)c1ccc(C(C)Sc2nnnn2Cc2ccco2)o1 +Cc1cnc(CCNC(=O)N2CCOCC2C2CC2)s1 +CCOc1c(C)cc(-c2cn[nH]c(=O)c2CO)cc1C +Nc1ccc2nc(C(=O)N3CCCc4ccccc43)cn2c1 +CC(NS(=O)(=O)N(C)C)c1cccc(N2CCCC2)c1 +CCOc1ccc(-c2noc(CSc3nnc(C)s3)n2)cc1 +CC1CN(CC(=O)c2cccs2)CCN1C(=O)OC(C)(C)C +Cc1noc(C2CN(C(=O)Cn3ccc4ccccc43)C2)n1 +Cn1ncc(-c2ccc3c(c2)CCCC3)c(CO)c1=O +O=C(NCCN1CCOCC1)N(Cc1ccccc1F)C1CC1 +COc1cccc(C(=O)CCNc2ccc(NC(C)=O)cc2)c1 +Cc1ccc(S(=O)(=O)NCc2ccc(NC(=O)C3CC3)cc2)cc1 +CC(C)Oc1ccccc1NC(=O)C1CC(=O)N(C)C1 +Cc1ccn(-c2ccccc2NCc2ccc3c(c2)CCO3)n1 +COc1ccc(-c2noc(N3CCC(C(=O)NC4CC4)CC3)n2)cc1 +Cc1cc2c(=O)n(CC(=O)NC(C)C(C)C)cnc2s1 +CCN(CC)C(=O)CCC(=O)Nc1cnc(C(C)(C)C)nc1 +Cc1cc(C(=O)N2CCN(Cc3cscn3)CC2)n(C)n1 +N#CCOc1cc(C(=O)N2CCC(C(N)=O)CC2)ccc1N +CN(CCC#N)C(=O)CSc1ccc(Cl)cc1N +O=C(Cc1coc(-c2ccc(F)cc2)n1)N1CCOCC1C1CC1 +COc1cc(C)ccc1OCCC(=O)NC1CCCCC1 +Cc1cc(C)cc(OC(=O)CCCCNC(N)=O)c1 +CCCNC(=O)CS(=O)(=O)c1ccc(C(=O)C(C)C)cc1 +O=C1CC2(CCN(C(=O)CCc3cccc(Cl)c3)CC2)CN1 +Cc1nnc(CNC(=O)c2ccc(C(F)(F)F)cc2)n1C +COc1ccc(-n2nnnc2SCCCCO)cc1 +O=C(Nc1ccccc1Cn1cncn1)NC1CCCCC1 +CCOC(C)c1noc(-c2cccc(OC)c2F)n1 +CCc1nc(C2CCCN2C(=O)CC2CCCO2)no1 +CCC1CCCCN1C(=O)CCc1c(C)noc1C +COc1cccc(NC(=O)Nc2nnc(-c3cccs3)o2)c1OC +COc1ccc(CNC(=O)c2cc(C)cc(C)c2)cc1OC +CC(C)(C)OC(=O)NCC(O)c1ccc(C(F)(F)F)cc1 +Cc1ccccc1-n1ccnc1SCC(=O)N1CCOCC1 +CC(NC(=O)NC1CCCCC1)c1cnn(C)c1 +O=C(NCC(O)C1CCCCC1)c1nc2ccccc2s1 +Cc1csc(C2CN(c3c(C#N)c(=O)n(C)c(=O)n3C)CCO2)n1 +CNC(=O)c1cccc(NCc2ccc(C#N)cc2)c1C +COc1cccc(C(=O)Nc2cccc(C(=O)C3CC3)c2)c1 +CCN(C(=O)CCc1ccc(N2CCCC2)c(N)c1)C(C)(C)C +COc1ccc(-n2ncc3c(=O)n(Cc4ccccn4)cnc32)cc1 +CCNC(=O)c1cn2ccnc(-c3ccc(F)cc3)c2n1 +CCc1ocnc1C(=O)N1CCC(Cc2occc2C(=O)OC)CC1 +CC(C)n1c(CCN2CCN(c3ccc(Cl)cc3)CC2)n[nH]c1=O +O=C(Cn1nc(-c2cccs2)oc1=O)NCCc1cccs1 +COC(=O)c1ccc(S(=O)(=O)N(C)C2CCCCC2)o1 +O=C(NCCCN1CCOCC1)c1ccc(Cn2cccn2)cc1 +Cc1ccc(C(=O)N2CCN(C(=O)c3ccc(C)cc3)CC2)cc1 +CC(=O)NCC1NCCc2cc(OC(F)(F)F)ccc21 +COC(C)C(=O)N=c1[nH]ccn1Cc1ccc(Br)cc1 +FC(F)(F)c1csc(CNc2cccc3c2OCCO3)n1 +COc1cccc(C(O)CCNc2c(C)cc(C)cc2C)c1 +Cn1c(=O)ccn(CC(=O)OCc2ccccc2)c1=O +O=C(c1cc(-c2ccco2)on1)N(Cc1cnc2ccccn12)C1CC1 +C#Cc1cccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)c1 +CC(C)Cc1ccc(C(=O)N2CCC(O)CC2)cc1 +CNC(=O)CNC(=O)c1ncoc1-c1cccs1 +CNS(=O)(=O)c1ccc(CCC(=O)N2CCCC2(C)C)cc1 +C#CCOCC1CCCN(C(=O)c2ccccc2C(F)(F)F)C1 +COc1ccc(CN2C(=O)CCS2(=O)=O)cc1C +CCCNC(=O)c1ccc(NC(=O)C(OC)c2ccccc2)cc1 +COCc1ccc(C(=O)Nc2nc(-c3ccccc3OC)cs2)o1 +CCOCc1ccc(CNC(=O)CN2CCOCC2C)cc1 +NC(=O)C(NCC(F)(F)F)c1c(F)cccc1F +Cc1c(NC(=O)c2ccc(-c3ccccc3)cc2)cnn1C +Cc1noc(C(C)C)c1C(=O)Nc1ccc[nH]c1=O +CN(C(=O)c1cn(C)nc1-c1cccs1)c1nccs1 +CC(C)n1nc(CNC(=O)c2ccsc2)c2ccccc21 +O=C(Cc1ccccc1)N1CCC(=O)N(CC2CC2)CC1 +COCCCC(=O)NC1CCN(c2c(F)cccc2F)C1=O +CC(C)(C)NC(=O)N1CCC(OC2CCCC2)CC1 +Cc1cccc(OCCn2c(CO)nc3cc(C)ccc32)c1 +CC(=O)NC1CN(C(=O)CCc2ccsc2)CC1c1ccc(C)o1 +COc1ccc(-c2c(C)cn(C)c(=O)c2C#N)cc1OC +Oc1c2ccc(-c3ccc[nH]3)nc2nn1-c1ccccc1 +COc1ccc(-c2noc(N)c2-c2ccccn2)cc1 +CC(CO)NC(=O)c1ccccc1Cc1ccccc1 +CCC(=O)N1CCCc2cc(NC(=O)c3cccc(OC)c3)ccc21 +COc1ccc(CNC(=O)N(C)C(C)C)c(OC)c1 +CCN(CC)C(=O)c1ccc(Cl)c(N2CCCCS2(=O)=O)c1 +CCn1nc2c(cc1=O)CN(Cc1nc(-c3ccco3)oc1C)CC2 +COc1cccc(C(=O)Nc2cccc(C)n2)c1OC +Cc1cc(N2CCC(CO)C2)ccc1Br +O=C(CNC(c1ccccc1)c1ccccc1)NC1CC1 +O=C(OCc1ccccn1)c1sccc1OC(F)F +Cc1ccc(C(=O)Nc2nc(-c3ccccc3C)cs2)cn1 +Cc1cc2c(c(N)nn2C)c(Oc2ccccc2)n1 +CC(=O)Nc1ccc(NC(=O)Nc2nn(-c3ccccc3)cc2C)cc1 +CCc1ccc(CN(C)C(=O)Nc2ccnc(C(=O)N(C)C)c2)cc1 +CN(C)C(=O)Nc1ccccc1OS(C)(=O)=O +COc1ccc(-c2nnc(SCc3n[nH]c(=O)[nH]3)n2N)cc1 +CCOC(=O)CSc1nc(N)c(NC(=O)c2ccccc2)c(=O)[nH]1 +Cc1ccoc1C(=O)N1CCN(c2ccc(S(N)(=O)=O)cc2)CC1 +O=C(CNC(=O)Nc1nccs1)Nc1cccc2cccnc12 +CNC(=O)C(C)NC(=O)NCc1cc(OC)ccc1Br +O=C(COC1CCCCC1)Nc1cc(-n2cnnn2)ccc1Cl +COCCNC(=O)c1c(-c2c(Cl)cccc2Cl)noc1C +Cc1ccc(-c2nc3nc(C)cc(NC(C)C)n3n2)cc1 +C=CCn1c(C)nnc1SCC(=O)Nc1cc(C(C)(C)C)no1 +CCC1(CC)Oc2cc(N)ccc2N(CC(O)CO)C1=O +CNC(=O)c1cc(Cl)ccc1NCc1cn2cc(Cl)ccc2n1 +CCOc1ccc(C2=CCN(C(=O)c3ccco3)CC2)cc1 +CCCCn1nnnc1CN1CCc2nn(CCC)c(=O)cc2C1 +CCCCN(C(=O)CCc1ccco1)c1ccccc1 +CCC1CN(C(=O)NCc2cc(C)on2)CCO1 +Cc1cc(NC(=O)c2c(Cl)cccc2Cl)no1 +CCOC(=O)c1c(C)csc1NC(=O)c1cc(F)ccc1F +N#Cc1cn(CC(=O)NCCC2=CCCCC2)c2ccccc12 +N#CCCCOc1cccc(CN2CCOC3(CCCC3)C2)c1 +Cc1ncsc1C(=O)OCCc1cnn(C)c1 +CCC(O)c1c(C)nn(Cc2cccc(Cl)c2)c1C +CCC(NC(=O)N1CCC(C#N)CC1)c1ccccc1OC(C)C +Cc1occc1C(=O)N=c1[nH]ccn1Cc1ccccc1Cl +Cn1cc(-c2nnc3sc(-c4cccc(Cl)c4)nn23)cn1 +COC1CCC2C1OCCN2C(=O)c1cnccn1 +Cc1cc(NC(=O)c2ccc(-n3cncn3)cc2)c2ncccc2c1 +Cc1cccc(N2CCN(C(=O)NC3CC3)CC2)c1C +Cn1ccnc1CN1CCC2(CC1)CCN(CC1CCCC1)C2=O +COc1cccc(OC)c1C(=O)NCC(=O)c1ccc(C)cc1 +C#CCN1CCC(C(=O)NC(c2ncccc2C)C(C)C)CC1 +CCOC(=O)c1cc(NC(=O)Nc2cccc(OC)c2)c(C)nc1C +N#Cc1cccnc1SCC(=O)Nc1ccc2c(c1)OCO2 +Cc1nc2cc(C(=O)N3CCC(Nc4ccccc4)C3)ccc2n1C +COC(=O)C(NC(=O)c1cc2cc(Cl)ccc2[nH]1)C(C)C +COCCN1CCN(C(=O)NCC(C)(C)CC(C)C)CC1=O +Cc1cnn(CCC(=O)Nc2ccc3c(c2)COC3)c1 +CCCCOC(=O)c1cccc(-n2nnc(C(N)=O)c2C)c1 +O=C(Nc1cn[nH]c1)NC1(c2cccc(Br)c2)CCC1 +CC1Oc2ccc(NC(=O)c3cc4c(F)cccc4[nH]3)cc2NC1=O +CCOc1ccc2c(C(=O)N3CCOCC3)cc(=O)oc2c1 +Nc1oc(C2CC2)cc1C(=O)c1c(F)cccc1F +Cc1oc(-c2ccno2)cc1S(=O)(=O)NC(C)(C)C +O=C(CCSc1nc2ccccc2s1)NCC(=O)N1CCCC1 +O=c1cnc2ccccc2n1CCOc1ccc(F)cc1 +O=C(CCCn1cncn1)N1CCOC(Cc2ccccc2)C1 +CC1CCCC(NC(=O)N2CCC(C(=O)N(C)C)CC2)C1 +Cc1ccc(N2CC(C(=O)Nc3ccccn3)CCC2=O)cc1C +Cc1ccccc1NC(=O)C(C)N1CC(C)Oc2cc(N)ccc21 +O=c1c2cnc3nc(-c4ccncc4)nn3c2ccn1C1CCCCC1 +COc1csc(C(=O)OCCc2c(C)[nH]c3ncnn3c2=O)c1 +COC(=O)c1cc(S(=O)(=O)Nc2cc(Cl)ccc2C)cn1C +COC1CCCCC1Nc1cc(C(N)=O)ccc1Cl +CC(=O)NC(C)C(=O)NCc1cn2cc(Cl)ccc2n1 +O=C(CSc1ncccn1)Nc1ccc(Cl)c(Cl)c1 +CC(NC(=O)c1ccc(F)nc1)c1cccc(N2CCOC2=O)c1 +Cc1cccc(C(C)C)c1NC(=O)CC1CCCO1 +CCOc1ccc(NC(=O)NCc2cccc(C#N)c2)cc1F +CCC(CO)NC(=O)c1csc(-c2ccc(Cl)cc2)n1 +CN1CCN(C(=O)c2ncoc2-c2ccccc2)CC1 +Cc1nc(NCC2CCC2)sc1C(=O)Nc1ccccc1 +Cc1cccc(NC(=O)COc2ccc(S(C)(=O)=O)cc2)c1C +COc1cc(CCNC(=O)c2cccc(NC(C)=O)c2)ccc1C +CC(=O)c1c(C)nc(C)nc1SCC(=O)Nc1ccc(F)cc1 +Cc1nn(C)c(C)c1CCC(=O)NC(C)c1ccccc1 +COCc1ccc(CNC(=O)CSc2cccc(C)c2)cc1 +CCC1CCCN(C(=O)CCCNC(=O)c2ccco2)C1 +COc1cc(NC(N)=O)c(OC)cc1Br +Cc1ccc2c(c1)SC(C(=O)Nc1c[nH]ccc1=O)C2 +CCn1ccc(C(=O)Nc2cc(-c3nnc(C4CC4)o3)sc2C)n1 +CC(C#N)CN(C)S(=O)(=O)c1ccc(F)cc1F +Nc1cccc(C(=O)CN(Cc2ccccc2)Cc2ccccc2)c1 +CC(C)C(Cc1ccc(F)cc1)NC(=O)NC1CCCNC1=O +Nc1ccc(S(=O)(=O)CCOc2cccc(Cl)c2)cc1 +CCc1cnc(CN(C)C(=O)c2ccc(-n3ccnn3)cc2)s1 +Cc1csc(CCNCc2c(C)n[nH]c2C)n1 +Cc1nc(C)c(CCNC(=O)c2ccc3cc[nH]c3c2)s1 +Cc1nnc(NC(=O)c2cc3ccc(Cl)cc3n2C)s1 +Cc1cc(C(=O)Nc2ccc3c(c2)NC(=O)CS3)no1 +COC(=O)c1c(Cl)cccc1Oc1nc(OC)nc(OC)n1 +CCCC(C)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 +COCc1nc2ccccc2n1CC(O)COc1cccc(C)c1 +Cc1nc(NC2CCC(O)CC2)c2c3c(sc2n1)CCC3 +O=C(Nc1ccc(N2CCNC2=O)cc1)c1scnc1C1CC1 +C#Cc1cccc(NS(=O)(=O)c2ccccc2OC)c1 +Cc1ccc(NC(=O)C2CCOCC2)cc1Br +Nc1cccc(-c2nnc(-c3cc(=O)cc[nH]3)o2)c1 +CC(O)(CNC(=O)NCc1ccnc(OC2CCC2)c1)c1ccco1 +CC(NC(=O)COc1ccc(C#N)cc1)c1ccccc1 +Cc1cc(C)nc(C2CCCCN2c2cnccn2)n1 +NS(=O)(=O)c1cccc(CNc2ncnc3ccsc23)c1 +CC(CO)NC(=O)C(C)Oc1ccc(-c2ccccc2)cc1 +COC(=O)CCC(=O)NCc1cc(F)ccc1Br +Cc1nc2cc(NC(=O)c3ccc4nccnc4c3)ccc2o1 +COCCS(=O)(=O)NCc1cccc(C#CCO)c1 +COCc1nsc2c1c(Br)cn2C +CN(CC(F)(F)F)C(=O)c1n[nH]c2ccccc12 +CC(C)(C)NC(=O)CCNC(=O)c1ccc(Br)cc1 +CC(Cc1nnc(SC2CCOC2=O)o1)c1ccccc1 +O=C(NCC(O)COc1ccc(F)cc1)c1ccc(F)cc1Cl +CCN(CC(C)C#N)S(=O)(=O)c1ccc(Cl)cc1C +COC(=O)NCCOC(=O)c1cnn(-c2ccccc2)c1 +O=C(NCc1ccc2c(c1)CCC2)Nc1cccc(N2CCCC2=O)c1 +O=S(=O)(Cc1ccc(Cl)cc1Br)NCCO +COC(=O)N(C)CCCC(=O)Nc1cc(-c2ncco2)ccc1C +N#Cc1cnc(NC(=O)NC2CCCCC2)s1 +CC(C)(O)c1nnc2c(-c3ccccc3)ccnn12 +CCS(=O)(=O)N1CCC(NC(=O)c2ccccc2O)CC1 +CCn1nc(C)cc1C(=O)Nc1nc2c(OC)ccc(C)c2s1 +Cc1cc(C)n(-c2cncc(N3CCC(N4CCNC4=O)CC3)n2)n1 +O=C(Nc1ccccn1)C1CN(C(=O)c2ccc3c(c2)OCO3)C1 +Cc1csc(N(C(=O)CCCNC(=O)C2CC2)C2CC2)n1 +CC(C)n1nc(O)c2c(-c3ccsc3)c3sc(=O)[nH]c3nc21 +CCOC(=O)c1noc2nc(C)n(Cc3ccccc3C)c(=O)c12 +Cc1ccc2ncc(C(=O)NCc3nc(C)c(C)s3)n2c1 +CCNC(=O)N1CCC(C(=O)OC)(c2ccccc2)CC1 +Cc1ccc(-c2nnc(C(C)N(C)Cc3cccs3)o2)cc1 +CCOC(=O)c1cc(C(=O)Nc2ccc(F)c(F)c2)n(C)n1 +CCOc1ccc(F)c(C(=O)Nc2ccc(C)c(NC(C)=O)c2)c1F +CCOc1ccc(CC(=O)Oc2ccc3c(c2)CCC(=O)N3)cc1 +O=C(Cc1ccc(Br)cc1)OCC(=O)N1CCCC1 +CCCCS(=O)(=O)N1CCCN(Cc2c(C)noc2C)CC1 +O=C(Nc1ccc2c(c1)OCCO2)c1nc2c(F)cccc2s1 +Cc1cc(Cl)ccc1OCC(=O)NC(C)(C)C +COc1cc(NC(=O)CC2CC3CCC2C3)ccc1N1CCCC1=O +CNS(=O)(=O)Cc1ccc(CNC(=O)C2Cc3ccccc32)cc1 +Cn1cc(C(=O)Nc2ccc(Nc3ccccc3)cc2)ccc1=O +COc1ccc(NS(=O)(=O)c2ccc(C)cc2)c(OC)c1 +Cc1cc(C)cc(NC(=O)c2cccc(C#N)c2)c1 +CCC(CO)NC(=O)NCC1(c2ccccc2C)CCOCC1 +O=C(COc1ccccc1F)NCC(F)(F)F +CCC1CCC(CNC(=O)c2scnc2C)CC1 +COc1ccc(OC(C)C)c(NCc2csc(C)n2)c1 +CCC(C)c1ccccc1NC(=O)COC(=O)c1cccn1C +Cc1cc(CN(C)Cc2nccs2)cc(C)c1OC(F)F +O=C(CCOc1ccccc1F)Nc1cccc(NC(=O)C2CC2)c1 +CCc1ccccc1NC(=O)c1cc(C)nn1CC +Cc1cn2nc(N3CCCC3c3noc(C(C)C)n3)sc2n1 +Nc1ccc2[nH]c(-c3ccc(Br)cc3F)nc2c1 +CCS(=O)(=O)N(C)CC(=O)N1CCc2cc(F)ccc2C1C +O=C(CCCNC(=O)c1ccco1)Nc1cc(F)cc(F)c1 +Cc1ccc(S(=O)(=O)Nc2ccc(C(=O)NCCO)cc2)cc1C +CCN(CCO)C(=O)C1CC(=O)N(c2cc(C)ccc2OC)C1 +COCCNC(=O)C1CC(=O)N(C2CCCC2)C1 +Cc1sc(=O)n(CC(=O)N2CCOC(C)(C)C2)c1C +Cc1ccc(CN(C)C(=O)c2c(C)nn(-c3ccc(F)cc3)c2C)o1 +Cc1cnn(CCC(=O)Nc2ccc(Br)cc2O)c1 +CCOc1ncccc1C(=O)NCCc1ccccc1OC +Cc1onc(-c2ccccc2)c1C(=O)N1CCCC2(CCOC2)C1 +C=CC1CCN(C(=O)C2CCC(=O)N(c3ccc(C)c(C)c3)C2)CC1 +CCOc1nnc(CN2CCOC(c3nc(C)n[nH]3)C2)s1 +COc1cccc(CN2CCOC(C(N)=O)C2)c1OC(C)C +OCC1NCCc2cc(Cl)c(Br)cc21 +CN(Cc1ccc(F)cc1F)C(=O)Nc1cn[nH]c1 +CCCCCCSc1nnc(-n2nc(C)cc2C)n1N +COc1ccc(NC(=O)C2CC(=O)N(CCC(C)C)C2)cc1 +O=c1ccc2ccc(OCC(O)c3ccccc3F)cc2o1 +CCCC(=O)N(CCOC)c1nnc(-c2ccc(F)cc2)s1 +COc1ccc(NC(=O)NCc2cnn(C)c2C)c(Cl)c1 +CCOC(=O)c1ccccc1Nc1ncnc(N(C)C)c1N +O=C(Nc1ccc(S(=O)(=O)C(F)F)cc1)c1cccs1 +C=CCNC(=O)C(C)NC(=O)c1ccc(Cl)cc1 +COC(=O)CN(C(=O)Cc1nc(-c2cccs2)oc1C)C(C)C +Cc1ccc(OCCN(C)C(=O)c2c(C)oc3nc[nH]c(=O)c23)cc1 +O=C(Cc1ccc[nH]1)NCc1ccnc2ccccc12 +N#Cc1nnn(CCCc2ccccc2)c1C1CCC1 +CN(C(=O)c1ccccc1)C(C#N)c1ccc2c(c1)OCO2 +O=C(c1ccc2ncnc(N3CCCC3)c2c1)N1CCCCC1 +CCCNS(=O)(=O)c1ccc2c(c1)N(C)CCO2 +O=C(CNC(=O)c1cc2ccccc2oc1=O)OCc1ccccc1 +COCCCNC(=O)NC1(c2ccc(Br)cc2)CCC1 +COCc1ccc(CNC(=O)c2coc(-c3ccccc3)n2)cc1 +Nc1ccc(C(=O)NCc2n[nH]c(Cc3ccc(F)c(F)c3)n2)cc1 +Cn1cc(CC2C(N3CCOCC3)CCN2C2CCOCC2)cn1 +CCN(CC)C(=O)CN(CC)c1ccc(F)c(F)c1 +Cc1oc(-c2ccc(Br)cc2)cc1C(=O)NCCO +COc1ccc(C(O)Cc2nc3ccccc3n2C)cc1OC +O=C(Nc1nc2c(s1)CN(CC(=O)N1CCCCC1)CC2)C1CC1 +Cc1cccc(CNC(=O)COC(=O)c2cccc(C#N)c2)c1 +C#Cc1cccc(N(Cc2ccco2)S(=O)(=O)c2cn[nH]c2)c1 +COc1ccc(CC(=O)NCCn2ccc(-c3ccncc3)n2)cc1 +CCC(CC)c1nnc(NC(=O)NCCOC)s1 +Cc1ccc(-n2nnc(C#N)c2-c2cccnc2)cc1 +CNC(=O)COc1cccc(OCc2ccc(Cl)cn2)c1 +Cc1cnccc1CCNC(=O)Nc1cc(-c2ncco2)ccc1C +CC1(C)CN(C(=O)c2cccc(NC(=O)c3cccnc3)c2)CCO1 +CC(CC#N)NC(=O)c1ccccc1-c1ccc(Cn2cccn2)cc1 +COc1cccc(C(C)C(=O)Nc2cnccn2)c1 +CNc1nc(C(N)=O)c(NC(=O)c2ccc(F)c(Cl)c2)s1 +O=C(NC1CC1)C1CC(=O)N(Cc2ccccc2F)C1 +CSc1sc(C(C)=O)c(N)c1S(=O)(=O)c1ccccc1 +Cc1c(C(C)OC(=O)c2ccc3nncn3c2)oc2ccccc12 +CC(C)N(C(=O)C1CC(=O)N(CC(F)(F)F)C1)c1ccccc1 +COCc1nc(C(=O)NCC2CCC(C)(C)CC2)cs1 +O=C(NCc1nc2ccccc2[nH]1)c1cc(F)ccc1-n1cnnn1 +COc1cc(NCC2COc3ccccc3O2)ncn1 +Cc1nccc(CNC(=O)NC(C)CCc2ccccc2)n1 +O=C(NCc1ccccc1-n1ccnc1)c1ccc2cc[nH]c2c1 +Cc1nc(CN2CCOC3C(Oc4ncccc4F)CCC32)cs1 +CCc1nsc(N2CCN(Cc3cccc4[nH]ccc34)CC2)n1 +Cc1ncc(CNc2ccc(NS(C)(=O)=O)cc2)s1 +Cc1nc(N2CCOCC2)ncc1C(=O)N1CCCCCC1 +CCOc1ccc(C(=O)Nc2cc(=O)n(C)c(=O)n2C)cc1 +Cc1c(NC(=O)C2(C)CCCCC2)c(=O)n(-c2ccccc2)n1C +CN(CC(=O)N(CCC#N)CCC#N)c1cccc2ccccc12 +CCCS(=O)(=O)c1ccc(NCC(C)C)cc1 +Cc1nc(C(C)C)nc2c1CCC(=O)N2CCCN1CCOCC1 +FC(F)(F)Cn1cc(NCC2CC=CCC2)cn1 +CCN(Cc1nnnn1-c1c(C)cccc1C)CC(C)C#N +Cc1cc(C(=O)NC(C)c2ccc3ccccc3c2)nn1C +CC(C(=O)NC1CC1)C1CCN(S(=O)(=O)c2cccs2)CC1 +Cc1ccc(-c2noc(CCC(=O)c3ccccc3)n2)nn1 +Cc1cc(N2CCN(c3cnn(C)c3)CC2)ncc1Br +COc1ccc(CC(=O)Nc2cc(N)ccc2OC)cc1 +Cc1ccnc(NC(=O)c2cnc(N3CCCC3)nc2N)c1 +COC(=O)C(C)Sc1nnc(-c2ccccc2)s1 +CN(CC(=O)NC1CC1)C(=O)Cn1c(-c2cccnc2)noc1=O +CCCN(CC(=O)N1CC(C)OC(C)C1)CC(F)(F)F +Cc1cc(Br)ccc1C(=O)NCCNc1cnccn1 +Cc1noc(C)c1C(=O)N1CCC2(CC(N3CCCC3=O)CCO2)C1 +Cc1cc(C)n(-c2ccc(CNC(=O)N3CCNC(=O)C3)cn2)n1 +C#CCNC(=O)C1CC(=O)N(c2cccc(C)c2C)C1 +Cc1noc(C)c1C(C)NC(=O)Nc1cccnc1-n1cncn1 +CCOc1cc2c(cc1CNC(=O)C1CCC1)OC(C)C2 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccc2ccccc2c1 +Cc1ccc(NC(=O)Nc2ccc3c(c2)OCO3)cc1 +C#CCC(NC(=O)C1COc2ccc(Br)cc21)C(N)=O +COC(=O)C(NC(=O)c1cnns1)c1ccc(Cl)c(F)c1 +O=C(c1ccc2cn[nH]c2c1)N1CCN(c2cccc(Cl)c2)CC1 +Cc1[nH]nc(-c2ccc3c(c2)NC(=O)C(C)O3)c1N +COCCNC(=O)c1nc(-c2cccs2)nc2c1OCO2 +CN(Cc1ccc(F)cc1F)S(=O)(=O)c1ccc(C#N)cc1 +CN1CC(C(=O)N2C3CCC2CC(c2ccc(F)cc2)C3)CC1=O +COc1ccnc(NCC(c2cccs2)N(C)C)n1 +Cc1ccc(S(=O)(=O)n2nc(C)c3c2CC(C)(C)CC3=O)cc1 +COCc1cc(=O)[nH]c(Nc2cc(Cl)ccc2F)n1 +Cc1noc(C)c1C(C)NC(=O)Nc1ccnn1C1CCCCC1 +C#CCN1CCN(C(=O)NCCc2ccc(C)cc2C)CC1 +CCCCn1nc(-c2cccc(OC)c2)cc(CO)c1=O +CC1CCC(NC(=O)NC(C)c2cnn(C)c2)CC1 +Cc1cc(NC(=O)CCC2Cc3ccccc3NC2=O)[nH]n1 +O=C(Cc1ccccc1)NCC(=O)NC1CC1c1cccc(Cl)c1 +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1nc(CC(N)=O)cs1 +Cc1nn(C)cc1CN1CCN(c2c(C#N)cnc3ccccc23)CC1 +CCCn1cc(Br)cc1C(=O)N(CC)CC(=O)NC +CCn1nnc(NCc2cc(OC)c(OC)c(OC)c2)n1 +COC(=O)c1cccc(NC(=O)c2cc3ccccc3c(=O)[nH]2)c1 +CCCCCCNC(=O)c1sc(S(N)(=O)=O)cc1C +Cc1csc(-c2cn(CC(=O)Nc3ccc4c(c3)OCO4)cn2)n1 +O=C(Cc1ccc(Cl)cc1)Nn1cnc2ccccc21 +COc1ccccc1NC1CCN(C(=O)NCc2nc(C)no2)CC1 +Cc1cc(C)c2cc(C(=O)NC(c3n[nH]c(C)n3)C(C)C)[nH]c2c1 +COC(=O)CC1NCCc2cc(OC)c(OC)cc21 +CNC(=O)N1CCC(C(=O)Nc2ccc(Cl)cn2)CC1 +CC(=O)Nc1ccc(C(=O)NCCNC(=O)Nc2ccccc2)cc1 +FC(F)(F)c1cc(Br)c2[nH]cnc2c1 +Cc1ncn(-c2ccc(CNC(=O)CC(C)C)cc2)c1C +NC(=O)Cn1nnc2c(cnn2-c2ccc(F)cc2)c1=O +COCC(NC(=O)c1c(O)cc(Cl)cc1Cl)C(N)=O +Cc1cc(OC(C)C(=O)NC2CC2)ccc1C(C)C +CCC(C)C(C)NC(=O)N1CCN(C(=O)C(C)(C)C)CC1 +Cc1c(N)cnc(N2CCCc3ccccc32)c1C#N +COc1ccccc1OCC(=O)Nc1ccccc1CO +CC(C)N(CC1CC1)c1ccc2scnc2c1N +CCOC(=O)c1nc(-c2ccc(Cl)cc2)[nH]c1C +Cc1ccc(-c2csc(NC(=O)c3scnc3C3CC3)n2)s1 +N#CC1(c2nc(Cc3ccc(Cl)cc3)no2)CCC1 +O=C(c1cocn1)N1CCOCC1c1nccc(NC2CCC2)n1 +O=C(NC1CCCCNC1=O)NC(c1ccccc1)c1ccncc1 +Cc1csc2nc(CC(=O)N3CCCC3)[nH]c(=O)c12 +O=C(NCc1ccc2c(c1)OCO2)NCc1cscn1 +Cc1cc2occ(CC(=O)OCCn3cncn3)c2cc1C +Nc1ccc(OCCOCC(F)(F)F)c(Cl)c1 +Cn1c(=O)[nH]c2cc(C(=O)Oc3ccc4c(c3)OCO4)ccc21 +Cc1ccc(-c2ncco2)cc1NC(=O)CCC1CCC(C)O1 +Cc1cccc(C(=O)NCC(=O)c2ccccc2)c1 +CS(=O)(=O)N1CCC(NC(=O)NCc2cccc(F)c2)CC1 +CCC1=C(C(=O)OC(C)C)C(c2ccc(OC)c(O)c2)NC(=O)N1C +O=C(NCCc1ccccn1)c1[nH]c(-c2ccccc2)c2c1CCC2 +CCN1CCN(C(=O)c2ncn(-c3ccc(C)cc3)n2)CC1 +CC(C)Cn1c(N2CCOCC2)nc2c1c(=O)[nH]c(=O)n2C +CC(=O)Nc1ccc(SCC(=O)Nc2cccc(Cl)c2)nn1 +O=C(NCc1ccccc1)c1nccn1-c1ccccc1 +CC(=O)NCc1ccc(S(=O)(=O)NC2CCCCC2)s1 +Cn1cnc(CNC(=O)c2ccc(OCc3ccccc3C#N)cc2)n1 +COc1cc(-c2noc(-c3cccc(NC(=O)C4CC4)c3)n2)ccn1 +Cc1ccc(-c2nc(CNC(=O)C(C)O)[nH]c2-c2ccccn2)cc1 +Cc1c(C(N)=O)nnn1CC(=O)NC(C)c1ccccc1 +O=c1[nH]n(-c2nncc3ccccc23)c(=O)c2ccccc12 +CC(CO)CNC(=O)NCc1ccc(CN2CCOCC2)cc1 +FC(F)(F)c1nn(Cc2ccc3c(c2)OCCO3)c2ccncc12 +COC(=O)CCCS(=O)(=O)NC1CCOCC1 +O=C(c1cc[nH]n1)N(Cc1ccccc1)CC1(O)CCCC1 +Cc1ccc(-c2ncco2)cc1NC(=O)Cn1c(=O)[nH]c2ccccc21 +Cc1nc2cc3c(cc2n(CCCO)c1=O)OCCO3 +Cc1cccc(NC(=O)c2ccc3cc[nH]c3c2)c1C(=O)N1CCCC1 +Nc1nc(CSc2n[nH]c(N)n2)nc(Nc2ccccc2)n1 +Cc1ccc(-c2ccc(C#N)c(=O)n2CC2CCCO2)c(C)c1 +CCC(NC(=O)c1ccc(=O)[nH]c1)c1ccc(OC)cc1 +O=C(NCCCc1c[nH]c2ccccc12)c1cn2cccnc2n1 +CN(CCO)S(=O)(=O)c1ccc(Cl)c(N)c1 +OC(CN1CCOCC1)c1cccc(Br)c1 +COCCNC(=O)C1(c2cccc(Br)c2)CCOCC1 +Cc1ccc(-n2ccc(=O)c(-c3nc(-c4ccccn4)no3)n2)cc1 +O=C(NCCOc1cccc2cccnc12)c1cc2cc(=O)[nH]cc2[nH]1 +COc1ccc(OCCCC(=O)N=c2[nH]nc3cc(C)ccn23)cc1 +CCC(C)n1ncc(C(=O)Nc2ccc(OC)c(OC)c2)c1C1CC1 +COc1cccc(CC(=O)N=c2[nH]nc3ccccn23)c1 +CC(C)c1cccc(C(C)C)c1NC(=O)C(N)c1ccccc1 +O=C(NCc1cn(-c2ccccc2)nn1)NC1CCCCC1 +Cc1cccc(-c2noc(COc3ccccn3)n2)c1 +COc1ccc2nc(SCC(=O)Nc3cc(C)nn3C)[nH]c2c1 +CCOC(CC)C(=O)Nc1cccc(C(=O)NC(C)(C)C)c1 +O=c1nc(NCc2ccccc2)c2ccccc2[nH]1 +CNC(=O)c1ccc(NCC(=O)NC(C)(C)C)cc1 +O=C(c1ccc(N2CCCS2(=O)=O)cc1Cl)N1CCCCC1 +COC(=O)c1cccc(S(=O)(=O)Nc2cnn(C(C)(C)C)c2)c1 +CC(Cn1cccn1)NC(=O)c1cc(Cl)c2c(c1)OCCCO2 +CNC(=O)c1ccccc1NC(=O)c1cc(OC)c(OC)cc1C +COc1ccc(CCN(C(C)=O)c2nc(C)cs2)cc1OC +Cc1nc2ccc(C(=O)Cn3cc(N)cn3)cc2o1 +CCc1cc(C(=O)N2CCC(Oc3c(C)cccc3C)CC2)[nH]n1 +O=C(c1c[nH]c2ccccc12)N1CCCC(COCc2ccccc2)C1 +Cn1cnnc1SCCC(=O)Nc1ccccc1Br +O=C(CC1Oc2ccc(Cl)cc2NC1=O)NCc1ccco1 +CC(C)Oc1ccc(NC(=O)NCc2cccc(C(N)=O)c2)cc1 +CN(CCCCNC(=O)c1cccn1C)c1ccccc1 +Cc1cccc(N2C(=O)Cn3c2nc2c3c(=O)n(C)c(=O)n2C)c1 +FC(F)COc1ccc(-c2nc(-c3cnccn3)no2)cn1 +CC1CCCN(C(=O)CSc2nnc(CO)n2C2CC2)C1 +Cc1ccc(N)cc1S(=O)(=O)Nc1cnn(C)c1 +COC(=O)c1ccc(SC(=O)N(C)C)cc1O +N#Cc1cccc(NC(=O)CCSc2nc(C3CCCC3)n[nH]2)c1 +CCn1cc(NC(=O)NCCC2CCCC2)cn1 +CCOC(=O)CN1C(=O)C(C(C)C)Oc2ccc(C(=O)CC)cc21 +Cn1c(=O)c2ccc(C(=O)OCC3CC=CCC3)nc2n(C)c1=O +NC(=O)C1CN(Cc2c[nH]nc2-c2ccc(F)cc2)CCO1 +CCn1c(SCc2nc3cc(F)ccc3n2CC)nnc1C1CC1 +Cc1ccc(OCCCOc2ccc[nH]c2=O)cc1 +C=CC(O)(C=C)CCC1CC2(CCC1=O)OCCO2 +CCNC(=O)c1ccc(NC(=O)CNC(=O)CC(C)(C)C)c(C)c1 +O=C(NCC1CCCC1O)NC1CCN(c2ccc(F)cc2F)C1 +COC(=O)N(C)c1ccc(NC(=O)CCc2c(C)n[nH]c2C)cc1 +N#Cc1cccc(NC(=O)CCCn2cccn2)c1 +COC(=O)c1ccc(NCc2csc(C)n2)c(F)c1 +CNS(=O)(=O)c1cccc(NC(=O)CNC(N)=O)c1 +Cc1ccc(N)cc1NC(=O)CCSc1nncs1 +CCCCNC(=O)OCn1c(=O)oc2cc(Cl)ccc21 +O=C(Nc1ccc(OC(=O)C2CCCO2)cc1)c1ccsc1 +COC(=O)c1ccc(CN2CCN(C(=O)C3CC3C)CC2)s1 +CCN(CC(C)(C)O)C(=O)NCC1CCOC1C(C)(C)C +COc1ccccc1CNS(=O)(=O)c1cccs1 +CCCN(Cc1cccc(Cl)c1)C(=O)c1ccoc1 +Nc1ccc2nc(CC(=O)NCc3nccs3)ccc2c1 +CC(Sc1ccccc1)C(=O)Nc1nc(-c2ccccn2)cs1 +CN(CCC#N)C(=O)CCc1ccccc1Br +COC(=O)C1CCCN(Cc2c(C)nn(-c3ccccc3)c2C)C1 +Cc1cc(C(=O)OCCCc2ccncc2)sc1C +Cc1ccc(SCCC(=O)NCc2cccnc2)cc1 +N#Cc1c(F)cccc1NCCc1nnc2n1CCCC2 +CCC(C)NC(=O)NCc1cn(-c2ccc(OC)cc2)nn1 +C#CCNC(=O)NC(c1ccc(OC)cc1)C(C)C +CCOc1ccccc1CNC(=O)c1cc(C)n(CC)c1C +CN(C)C(=O)Cc1ccc(NC(=O)c2ccsc2)cc1 +CC1CCC(C(=O)Nc2cnn(-c3ccccc3)c2C(F)(F)F)O1 +CC(CC#N)NS(=O)(=O)c1cc(Cl)cc2c1OCC2 +O=C(NCCC(=O)N1CCCCCC1)NC1c2ccccc2CC1O +O=C(Nc1ccccc1)N1CCCC1c1ccco1 +O=C(OCC1CC1)c1cnc(C2CCCO2)s1 +COc1cc(C(C)=O)ccc1OCC(O)Cn1cnc2ccccc21 +c1coc(-c2cc(CSc3nccn3C3CC3)no2)c1 +C=C(C)Cn1nc(CO)cc1-c1cc(C)ccc1OC +CCCOCC(=O)NCC(=O)Nc1ccc(Br)cc1 +Cc1ccc(C(=O)CCC(=O)NCCc2ccc3c(c2)OCO3)cc1 +c1cc(-c2ccnn2Cc2ccc3c(c2)OCCO3)ccn1 +CNc1ccc(S(=O)(=O)NCc2ccsc2)cc1 +CC(C)CC(O)CNC(=O)c1ccc(Cl)c(C#N)c1 +CCCCNC(=O)c1ccccc1NS(=O)(=O)c1ccccc1 +c1cncc(-c2noc(CN3CCCOc4ccccc43)n2)c1 +Cc1cc(NC(=O)C2CNC(=O)C2)c2ncccc2c1 +CCN(C(=O)c1csc(COC)n1)c1ccccc1C +Cc1nc(CCNC(=O)NC(C)C(=O)N2CCCCC2C)cs1 +Cc1noc(C)c1S(=O)(=O)NCCC(=O)Nc1nccs1 +CCCCCS(=O)(=O)N(C)CC1CCCCO1 +COc1cccc2cc(CNc3cccc(-n4nnnc4C)c3)oc12 +CCOC(=O)CCCNC(=O)Nc1ccccc1Br +CC(C)c1csc(NC(=O)CCn2cncn2)n1 +CCN(CC)C(=O)c1cc(C2CC2)nc2c1c(C)nn2-c1ccccn1 +COC(=O)c1sc2nc(COCc3ccccc3)[nH]c(=O)c2c1C +CN(C)C(=O)c1ccccc1NC(=O)CCc1cccc(N)c1 +O=C(NCc1cccc(C(F)(F)F)c1)c1ccccc1-n1cnnn1 +CCCc1cc(C(=O)Nc2cnn(Cc3ccccc3C)c2)no1 +O=C(C1CCC1)N1CCC(n2c(C3CCCC3)nc3cccnc32)C1 +COc1cc(F)ccc1NC(=O)c1cnn(Cc2ccccc2)c1 +Cc1n[nH]c(C)c1NC(=O)Nc1ccc(-c2nc(C(C)C)no2)cc1 +COc1ccc(OC)c(S(=O)(=O)Nc2cccc(O)c2)c1 +C#CCNC(=O)c1ccccc1SCc1nc(C)no1 +NC(=O)c1ccsc1NC(=O)c1cccc2ccccc12 +CC(C(=O)Nc1ccc(-c2ccccc2)cc1)n1cccn1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCC1CCCO1 +COc1ccc(Nc2ncnc(NCc3ccco3)c2N)cc1 +Cc1ccc(OC(=O)C(NC(=O)c2ccco2)C(C)C)cc1C +COc1cccc(C(=O)c2ccccc2F)c1OC +Cc1cccn2cc(C(=O)NCc3cc(F)ccc3F)nc12 +CC(C)Oc1ccccc1CNc1ccc(CN2CCCC2=O)cc1 +Cc1nc2ccc(NC(=O)Nc3ccc(O)cc3C)cc2o1 +CCc1cc(N)c2c(c1)NC(=O)C(c1ccccc1)O2 +Cc1nn(C)c2nc(NCCCn3cc(Cl)cn3)sc12 +CCNC(=O)c1ccc(NCC2CC=CCC2)cc1 +Cc1nn(C)c(=O)c(C(=O)NCCC(=O)NC2CCCCC2)c1C +Cc1cccc(NC(=O)CCc2nc(C(C)(C)C)no2)n1 +COC(=O)c1cc(Cl)c(NC(C)=O)cc1OC +Nc1ccc(C(=O)CCN2CCCc3ccccc32)cc1 +COc1ccccc1-n1nnc(C(=O)Nc2ccc(Cl)cc2)c1C +CCS(=O)(=O)c1ccc(NCc2ccccc2F)cc1 +Cn1cc(Br)cc1C(=O)Nc1cnc2ccccc2c1 +CC(Sc1ccc2c(c1)OCCO2)C(=O)Nc1ccnn1C(C)C +COc1cc(C(=O)N(Cc2cccnc2)C(C)C)cc(OC)c1C +COCCNC(=O)CN1CCN(c2c(C)n[nH]c2C)CC1 +CC(=O)c1cc(F)ccc1OCC(=O)NC1CCOc2ccccc21 +CNC(=O)c1ccc(NS(=O)(=O)c2cccc(Cl)c2)cc1 +CCOC(=O)C(CC)N1CCCOc2ccc(N)cc21 +O=C(c1ccc(-c2cccs2)nc1)N1CCc2[nH]c(=O)sc2C1 +Cc1nc2ccc(NC(=O)c3cc(F)c(F)c(F)c3F)cc2s1 +CC(CO)C(C)NC(=O)NCc1ccccc1Oc1ccccc1 +COCC(O)CN(C)C(=O)COc1ccccc1F +Cn1ncc(-c2ccccc2)c1C(=O)NC1CCCCC1 +O=C(c1ccccc1F)N1CC(OCc2ccc(Cl)cc2)C1 +CC(=O)N1CCC2(CC1)C(=O)N(c1cccnc1)c1c(F)cccc12 +CC(C)c1ccccc1NCCCN1CCOCC1 +CC(OCC1CC1)C(=O)NC1CCCN(S(C)(=O)=O)C1 +Cc1ccc(OCc2nnc(-c3cccs3)o2)nc1 +COCCNC(=O)CN1C(=O)C(C)(C)Oc2cccc(N)c21 +Cc1ccc(OCC(=O)Nc2cccnc2)c(C)c1 +O=C(NCc1cc(Cl)c2c(c1)OCCO2)c1n[nH]c(=O)[nH]1 +O=C(c1ccco1)N1CCC(Nc2nccn3cnnc23)CC1 +COc1ccccc1NC(=O)CSc1ccc(N)cc1 +Cc1ccccc1COC1CCN(C(=O)c2n[nH]c3ccccc23)CC1 +CCOCCC(=O)N1CCC(C(=O)OC)c2ccccc21 +Cc1cc(C(=O)Nc2nc(-c3cc4ccccc4o3)cs2)nn1C +N#Cc1ccccc1NCCC(=O)c1ccc2c(c1)CCC2 +CCCCn1nc(C)cc1NC(=O)c1cc(-c2cnn(C)c2C)no1 +OCc1cc(CC2(NCc3ccccc3F)COC2)no1 +Cc1ccc(C(=O)N(C)CC(=O)N(C)C)cc1NC(=O)c1ccco1 +Cc1nc(COc2ccccc2C(=O)NC2CC=CCC2)no1 +Nc1nc(-c2ccc3c(c2)OCO3)ccc1C(=O)NC1CC1 +CC(C)(C)c1noc(CCC(=O)N2CC3C(C2)C3(C)C)n1 +CC(C)n1c(CCNC(=O)c2cccc(Cl)c2)nc2cccnc21 +CC(=O)c1cc2c(cc1NC(=O)c1cc3c(s1)CCC3)OCO2 +Clc1ccc(CNCc2cscn2)cc1Cl +C#CCNC(=O)N1CCCN(C(=O)c2ccccc2Cl)CC1 +COC(=O)c1c(SC)nc(-c2ccccc2)[nH]c1=O +Cc1nc2ccc(NC(=O)CNC(=O)Cc3ccccc3)cc2o1 +O=C(NCCNC(=O)c1ncoc1C1CCCO1)c1cccnc1 +CCNc1ncnc(NC23CC4CC(CC(C4)C2)C3)c1N +CC(=O)Nc1ccc(F)c(NC(=O)c2cn(C)nc2C(C)(C)C)c1 +CC(C)NC(=O)Cn1nnc(-c2ccccc2Cl)n1 +CCOC(=O)Cn1c2ccccc2n2c(=O)cc(CC)nc12 +CC(=O)Nc1cc(C(=O)Nc2ccc(OC(C)C)cc2)ccc1C +CCN(CC)S(=O)(=O)c1ccc2oc(=O)ccc2c1 +COc1ccc(CC(=O)Nc2ccn(-c3cccc(C)c3)n2)cc1 +CC1CC(=O)c2cc(C(=O)NCCc3cccs3)c(=O)[nH]c2C1 +Cc1ccc(NC(=O)CS(=O)(=O)c2nncn2C)cc1F +CC1CCN(S(=O)(=O)N(C)Cc2c(F)cccc2Cl)C(C)C1 +COc1ccc(F)c(NC(=O)NCCCn2nc(C)cc2C)c1 +Cc1cc(-c2noc(C(C)OC(=O)c3cccnc3)n2)ccc1F +CCOC(=O)c1sc2ncnc(N3CCC(C)CC3)c2c1C +N#Cc1nc(-c2ccccc2Cl)oc1N1CCOCC1 +NC(=O)c1cc(Cl)ccc1OCC(=O)NCC1CCCCC1 +COc1ccc(-c2noc(CC(O)c3cccc(F)c3)n2)cn1 +CNC(=O)c1ccc(CSc2cccc(C#N)c2)cc1 +COc1cccc(C2CC2C(=O)N2CCC(Cc3cnn(C)c3)C2)c1 +COC(=O)CN(Cc1ccc(F)c(F)c1)c1ccc(C#N)nn1 +COCc1nn2c3c(nnc2c1-c1cccc(Cl)c1)C(=O)CCC3 +CCc1nnsc1C(=O)NCc1ccccc1-n1cccn1 +O=C(NCCCO)Nc1ccc(C(=O)NCc2ccccc2F)cc1 +NC(=O)COc1ccc(NC(=O)NCCC2CC3CCC2C3)cc1 +CC1(C)Cc2cccc(OCC(=O)Nc3ccncc3)c2O1 +COC(=O)CCCC(=O)c1ccc2ccccc2c1 +O=C(CC(F)(F)F)Nc1cccc(C#CCO)c1 +NC(=O)c1cc(-c2ccccc2)sc1NC(=O)C1CC=CCC1 +OCC1CCCN1c1cc(N2CCOC(c3ccccc3)C2)ncn1 +CNC(=O)COc1ccccc1CC1COc2c(cccc2OC)C1 +O=C(Cc1cccs1)OC(C(=O)NC1CC1)c1ccccc1 +COc1ccc(C(=O)NCCNc2nc3ccccc3s2)c(F)c1 +O=c1nc(N2CCCC2)oc2cc3ccccc3cc12 +CCc1cccc(NC(=O)Nc2nnc(C3CC3)s2)c1 +Cn1ncc2c1CCCC2NC(=O)c1cc2c([nH]c1=O)CCCC2=O +O=C(NCc1ccccc1F)c1csc(Nc2ccccn2)n1 +CC(C)c1nc(C(=O)N2CC(C)C(N3CCOCC3)C2)c[nH]1 +CS(=O)(=O)c1ccccc1N1CCN(CCO)CC1 +Cc1ccc(OC(C)C(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1 +COc1ccc(Cl)cc1C(=O)N(C)CC(C)O +CC(=O)c1[nH]c(C)c(C(=O)NC2CCC(C(=O)N3CCCC3)C2)c1C +O=C(c1sccc1Br)N(Cc1ccco1)C1CC1 +Cc1csc(-c2cccc(NC(=O)NCC(C)(C)C(N)=O)c2)n1 +Cc1cc(C(=O)N2CCCCC2C2OCCO2)c2c(C)nn(C)c2n1 +Clc1cn[nH]c1-c1nn2c(C3CCC3)nnc2s1 +Cc1cc(C)c(CNC(=O)NCc2ccc3c(c2)OCCO3)c(=O)[nH]1 +CC(=O)NCC(=O)NCC(C)(C)c1ccc(Br)cc1 +CC(C)(C)CC(=O)N1CCCC1C(=O)Nc1ccc2c(c1)COC2 +Cc1noc(C)c1CC(=O)NC1CC(=O)N(CC2CCCCC2)C1 +Cc1nc(C(F)(F)F)c(-c2n[nH]c(-c3cccnc3)n2)s1 +Cc1cc(C)n(-c2ccc(CNC(=O)Nc3ccncc3)cn2)n1 +COc1ccc2c(CC(=O)Oc3ccc(C)cc3OC)coc2c1 +Cc1ccccc1N1CCN(C(=O)Cn2cc(Cl)cn2)C(C)C1 +Cc1ccc(S(=O)(=O)CCC(=O)Nc2ccc(Cl)cc2)cc1 +C=CCNC(=O)c1nc2ncc(Br)cn2n1 +CC(=O)NCCOc1cccc2c1N(C(=O)c1cccs1)CCC2 +CN(Cc1nc2ccccc2n1C)C(=O)CNC(=O)OC(C)(C)C +N#CCCN(C1CCOCC1)S(=O)(=O)c1ccc2ccccc2c1 +N#Cc1nsc(C(=O)N2CCC(C(N)=O)CC2)c1N +CC1(C)C2OCCC2C1OC(=O)c1cnc(C2CCCO2)s1 +O=C(Cn1cccn1)N1CCN(C2CCCCC2)CC1 +COc1ccc(C(=O)C(C)n2nc(C)cc2C)cc1 +COC(C)(C)c1noc(CCn2c(C)csc2=O)n1 +O=C(c1ccc[nH]c1=O)N1CCN(Cc2cc3ccccn3n2)CC1 +CCS(=O)(=O)N1CCCc2c(-c3cccnc3)nn(C)c2C1 +CCn1cc(CN(C)C(=O)CC23CC4CC(CC(C4)C2)C3)cn1 +OCCc1csc(COc2cc(Cl)cc(Cl)c2)n1 +COc1ccc(C(=O)OCC(=O)Nc2cc(C)n[nH]2)cc1OC +CC(NC(=O)C1CCC(=O)N1)c1ccccc1Br +Cc1[nH]ncc1C(=O)NCc1cccc2c1OCCCO2 +O=C(CSc1ncn[nH]1)Nc1ncc(Cc2ccc(F)cc2)s1 +O=C(Cn1c(C(O)c2ccccc2)nc2ccccc21)N1CCCC1 +CN(CCC(F)(F)F)C(=O)NCc1ccc(C(N)=O)cc1 +O=C(NC(C1CC1)C1CC1)c1cccc2c1OCO2 +CCOC(=O)c1c2n(c(=O)c3cnc(C)nc13)CCN2 +NC(=O)C(OC(=O)Cn1cnc2ccccc2c1=O)c1ccccc1 +Cc1cnc(NC(=O)C2(NS(C)(=O)=O)CCCCC2)s1 +Cc1c(C(=O)Nc2cccc(C#N)c2)oc2ccccc12 +COc1ccccc1C(O)CCC(=O)N1CCCCC1 +CCC(CC)(CO)NC(=O)c1ccc(OC)cc1O +COc1cccc(CC(=O)Nc2cc(F)ccc2OC)c1 +CC(=O)NCCNC(=O)NC(C)c1sc(C)nc1C +O=C(CNC(=O)c1ccc(F)cc1)Nc1ccc(F)cc1 +NC(=O)C1CCN(C(=O)CCc2ccc(Cl)cc2)C1 +CC(=O)Nc1cc(NC(=O)c2ccccn2)ccc1C +COc1ccccc1OCc1c(C#N)nnn1CCO +CCOc1ccsc1C(=O)N1CCC2OC(C)CC2C1 +CC1(C)C(=O)NCCN1C(=O)COc1ccccc1 +CCN1C(=O)C(C)(C)c2cc(S(=O)(=O)N3CCCCC3)ccc21 +Cc1ncc(CNC(=O)C2(c3ccc(F)cc3)CCOCC2)s1 +CC1Oc2ccc(N)nc2N(CC(=O)N2CCCC2)C1=O +Cn1c(COc2ccc(-n3cccn3)cc2)nnc1C1CC1 +Cc1noc(-c2ccc(C(=O)N3CCOCC3C3CC3)cc2)n1 +CC(CNC(=O)NC1CCCCC1)Cn1cccn1 +COc1ccc(C)cc1S(=O)(=O)NCc1nc(C)no1 +O=C(CN1CCN(C(=O)CN2CCOCC2)CC1)NCC1CCC1 +O=C(NCCc1nc2c(s1)CCCC2)c1ccccc1Cl +Cc1nnc2n1CC(NC(=O)c1ccc(Cl)cc1)CC2 +Cc1ccc(CSc2nc3ccccc3[nH]c2=O)cc1 +CCOc1ncccc1C(=O)OCC(=O)Nc1ccc(F)c(F)c1 +CCN(C(=O)C(C)S(=O)(=O)c1ccccc1OC)c1ccccc1 +COc1ccc(CC(=O)Nc2sccc2C#N)cc1C +Nn1c(SCc2cccc(F)c2)nnc1-c1cccnc1 +O=C(Nc1cnc(-c2cccc(Cl)c2)nc1)c1ccsc1 +O=S(=O)(Cc1ccccc1)NCCn1ccc(-c2ccncc2)n1 +CC1CCC(C(N)=O)CN1c1cccc(Cl)c1C#N +CC1(C)CCCN1C(=O)c1cn(-c2ccc(C(F)(F)F)cn2)nn1 +CC(C)C1C(=O)NCCN1Cc1cc(=O)oc2cc3c(cc12)CCC3 +CCOc1ccc(C#N)cc1NC(=O)NCc1ccc(O)c(OC)c1 +COc1cccc(CC(=O)NCc2cscn2)c1 +COc1ccc(OCC(=O)Nc2ccccc2N)cc1 +CCN1C(=O)C(C)(C(=O)N(C)Cc2cccs2)Oc2ccccc21 +CC(C)(CO)NC(=O)c1ccc(-n2cncn2)nc1 +Cc1ccc(C(=O)CCC(=O)Nc2cccc(-n3cnnc3)c2)s1 +CC(NC(N)=O)C(=O)NCc1cn2cc(Br)ccc2n1 +CC1COCCN1C(=O)C1COc2ccc(F)cc2C1 +CN(C)C(C(=O)NC1CCC(n2cnnc2)CC1)c1ccc(F)cc1 +Cc1noc(C)c1CS(=O)(=O)c1ccc(F)cc1 +C=C(C)CN(CC)C(=O)CN1CCOC(C(N)=O)C1 +N#CC1(NC(=O)c2c(F)c(F)cc(F)c2F)CCOCC1 +Cc1ccc(CNC(=O)CC2CCC2)c(OCC2CCOC2)c1 +Cc1cccc(S(=O)(=O)n2cc3c(=O)n(C)c(=O)n(C)c3n2)c1 +CCOCCCNC(=O)c1cccc(N2C(=O)CCS2(=O)=O)c1 +C=CCOC1C2CCCC1CN(c1nncs1)C2 +CCC(C)NC(=O)c1cc(F)ccc1Br +O=C(NCC1CCC1)Nc1ccc(-n2cncn2)cc1 +Cc1ccccc1NC(=O)NCc1cccc(NC(=O)c2ccco2)c1 +Cc1ccc(C2CC2C(=O)NCc2ccc(S(C)(=O)=O)cc2)s1 +O=C(Cn1ccccc1=O)Nc1ccc(C(=O)NC2CCCC2)cc1 +COCCn1c(SCC(=O)Nc2cc(C)on2)nc(C)c1C +Cn1cc(C(=O)OCC(F)(F)F)c(C(C)(C)C)n1 +CNC(=O)C(NC)c1ccc(OC)c(Br)c1 +Cn1ncc2c(N)nc(CSc3ccccc3)nc21 +Cc1cccc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1O +COCc1c(C(=O)Nc2cc(C(C)C)n[nH]2)oc2ccccc12 +CC(C)CC1COCCN1C(=O)CCc1ccncc1 +CC(=O)N1CCN(CC(=O)N2CCSc3ccccc32)CC1 +CN(Cc1cnc2ccccn12)c1nccc(-c2cccnc2)n1 +CCn1nnc(NCc2cc3c(cc2Cl)OCO3)n1 +Cc1ccc(F)cc1C(=O)Nc1ccc(N2CCNC2=O)cc1 +CC(=O)c1sc(CC(=O)Nc2ccc(C)cc2)nc1C +CCOC(=O)CC(NC(=O)c1ccccn1)c1ccc(F)cc1 +COc1ccc(OC)c(CC(=O)N2CCCCCC2)c1 +COc1ccc(CCNC(=O)c2ccc[nH]c2=O)cc1OC +COc1ccc(NC(=O)N(C(C)C)C(C)C)cc1 +CCC(C)NC(=O)c1ccc(N2CCCCC2)cc1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)c1cc(Cl)c[nH]1 +COc1ncccc1NC(=O)c1ccc(CSc2nccn2C)o1 +Cc1nnc(C(C)NC(C)c2cnn(Cc3ccccc3)c2)o1 +O=C(NCCCNc1cccc(F)n1)c1cccc(O)c1 +CC1c2ccccc2OC1C(=O)N1CCCCC1CCO +Cc1ccccc1CN(C)C(=O)c1ccc(S(N)(=O)=O)o1 +COc1ccc(CC(=O)n2nnc3ccccc32)cc1 +Cc1cc(CN(C)C(=O)c2cc(Cl)ccc2-n2cnnn2)no1 +COc1cc(CNC(=O)Cn2ccc3ccccc32)ccc1O +O=C(CCC1CCCCO1)NCC1(c2ccc3c(c2)OCO3)CC1 +Cc1cc(C(F)(F)F)nn1C(C)C(=O)N1CCN(C)CC1 +N#CCCN1CCOC(c2ccc(F)c(Cl)c2)C1 +Cc1noc(C2CCCCN2Cc2nc(-c3cccs3)no2)n1 +CCCOc1ccc(-c2nc(C#N)c(NC)o2)cc1 +COc1ccc(F)cc1COC(=O)c1ccc2c(c1)OCC(=O)N2 +CCCCn1nc(C(=O)NC(C)c2ccc(CC)cc2)ccc1=O +CCCn1nc(C)c(C(=O)NCc2c(F)c(F)cc(F)c2F)c1C +O=C(CCCN1CCOC1=O)NC1CCc2c(Cl)cccc21 +COCCN(Cc1cccc2c1OCCCO2)CC(F)(F)F +CC(O)CNC(=O)Nc1ccc(-n2cncn2)nc1 +Cc1csc(S(=O)(=O)C(C)C(=O)NC2CCCC(C)C2C)n1 +CC(=O)c1cccc(OCC(=O)Nc2cccc(S(C)=O)c2)c1 +CC(C)OCc1cccc(NC(=O)N2CCCC(CCC(N)=O)C2)c1 +O=S(=O)(NCC1CCOCC1)c1cccc(Br)c1 +Nc1occ(C(F)(F)F)c1C(=O)c1cscn1 +O=C(CNC(=O)c1ccc2sncc2c1)NCc1cccs1 +O=C(c1ccsc1)N1CC2COCC2(COCC2CC2)C1 +OC(CSc1nnnn1C1CCCC1)c1c(F)cccc1F +COC(=O)CCCS(=O)(=O)N1CCCC1C1CCCCC1 +COCc1nc(N)nc(Nc2ccc(Cl)cc2)n1 +Cc1ccc2c(c1)CCCN2C(=O)Cn1c(C)c(C)sc1=O +CC(NC(N)=O)C(=O)Nc1ccc(C(C)(C)C)cc1 +COCc1nc(-c2ccc(-c3ccccc3)nc2OC)no1 +COc1ccccc1-c1nc(C)nc(N2CCCC2)c1N +COCCC(=O)Nc1ccc(OCc2cccc(C#N)c2)cc1 +CC(=O)Nc1cc(S(=O)(=O)NCc2cccnc2)ccc1F +Cc1cc(NC(=O)C2CC2)sc1C(=O)OCC#N +CC(C)N(Cc1cccc(Cl)c1)C(=O)c1cnccn1 +CC(=O)c1ccc(NC(=O)c2cccc(OCC(F)F)n2)cc1 +COc1ccc(C2NC(N)=Nc3nc4ccccc4n32)cc1F +Cc1cnc(C(=O)N2CCCC3(CCC(=O)N3)C2)cn1 +COCCCNC(=O)CN1C(=O)COc2ccc(C)cc21 +CC(C)Cn1nnc(C#N)c1COc1ccccc1 +CSc1ncc(C(=O)NC2CCCC2)n1-c1ccc(F)cc1 +Cc1noc(C2CN(S(=O)(=O)c3cc(F)ccc3F)C2)n1 +CC1CCCC(CNC(=O)NC(CO)c2ccccc2)C1 +CCOC(=O)CNC(=O)c1cn(C)nc1-c1ccc(F)cc1F +COC(=O)c1cc(C(=O)OC)c(S(N)(=O)=O)s1 +COc1ccccc1NC(=O)CS(=O)(=O)c1ccc(C)cc1C +Cc1cccc(C)c1NC(=O)Nc1ccc(F)cc1 +OCc1cc(-c2cccs2)n(Cc2ccccc2)n1 +CS(=O)(=O)c1ccc2c(c1)nc(N1CCCCC1)c1nccn12 +N#CCCNC(=O)CN1CCCc2cc(F)cc(F)c21 +COc1cccc(N2CCN(C(=O)c3c(C)nn(C)c3C)CC2)c1 +NC(=O)CCSc1nnnn1C1CCCCC1 +COc1ccccc1OCC#CCNC(=O)NCc1ccc(F)cc1 +O=C(Nc1ccc(-c2nc3ccc(F)cc3[nH]2)cc1)c1cc[nH]n1 +Cc1nnc(SCC(=O)Nc2ccc(C)c(Cl)c2)s1 +CC1Cc2ccccc2N1C(=O)CCCNC(=O)C1(C)CCCO1 +COc1ccnc(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)c1 +CCNc1nc(-c2c(C)oc3c2CC(C)CC3)cs1 +O=C(NCCc1ccc(F)cc1)c1cnc(C2CCCO2)s1 +NC(=O)c1cc(Cl)ccc1NC(=O)C1CC1c1cccc(F)c1 +O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c(=O)c2ccccc12 +Cc1ccc(S(=O)(=O)CC(=O)N2CCCc3ccccc32)cc1 +COC(=O)c1c(C)[nH]c(C(=O)N(CCC#N)CCC#N)c1C +Cc1cc(Cl)ccc1S(=O)(=O)NCCOCC(C)C +O=C(NCc1ccsc1)Nc1cccc(C(F)(F)F)c1 +COCc1cccc(CNC(=O)c2ccc(F)cc2F)c1 +CC(=O)NC(CC(=O)NCCc1ccccn1)c1cccs1 +CN(CCc1ccc(F)cc1)C(=O)C1CC(=O)N(C2CCCC2)C1 +CN(CC(=O)NCC(C)(O)c1ccc(F)cc1)C(=O)OC(C)(C)C +CCCOc1ccc(Nc2nc(C)cc(=O)[nH]2)cc1 +CC(C)CN1CCOC(CNC(=O)CCc2ccc3c(c2)OCO3)C1 +COCc1noc(-c2cccc(-c3n[nH]c(C)n3)c2)n1 +Cc1cc(OC(C)C(=O)Nc2cccn(C)c2=O)ccc1C(C)C +Cc1nc(CN2CCN(C(=O)NC(C)c3ccccn3)CC2)cs1 +Cc1[nH]c2cc(-c3cccc(F)c3)nn2c(=O)c1CCC#N +O=C(N=c1[nH]nc2ccccn12)C1COc2ccc(F)cc2C1 +COc1ccc2[nH]c(C3CCN(C(=O)c4ccccc4)C3)nc2c1 +Cc1cccc(C(=O)NC(C(=O)N2CC(C)OC(C)C2)C(C)C)c1 +Cc1noc(C)c1CN(C)C(=O)CCNC(=O)c1ccco1 +COc1ccc(OC)c(C2CCCN2C(=O)CC2C=CCC2)c1 +O=C(NC1CCCc2c1cnn2-c1ccccn1)c1ccsc1 +O=S(=O)(NCc1cc[nH]n1)c1ccccc1F +Cc1c(C(=O)Nc2ccncc2)oc2c1C(=O)CC(C)(C)C2 +CCC(=O)NCC(=O)NCCc1cccc(Cl)c1Cl +NCC(=O)c1ccc(OCc2ccccc2Cl)cc1 +O=C(c1cccs1)N1CCC(OCc2ccccc2F)CC1 +Cc1occc1C(=O)Nc1sc2c(c1C(=O)OC(C)C)CCCC2 +O=C(OCc1cccnc1)c1cccc(N2CCOC2=O)c1 +CC(C)Oc1ccc(C#N)cc1NC(=O)c1ccco1 +COC(CNC(=O)NC(C)(C)C)c1ccc(C)s1 +N#Cc1cccc(NC(=O)CCC(=O)c2ccc3c(c2)CCC3)c1 +CCc1c(C)nc2nncn2c1NCc1ccccc1 +O=S(=O)(CC1CCCCO1)N(Cc1ccc(F)cc1F)C1CC1 +O=C(NCC(F)(F)F)C1CCc2ccccc2N1 +Cc1cccc(OCCNC(=O)c2ccncc2F)c1 +CCC(Oc1ccccc1)C(=O)Nc1cccc(C)n1 +Cc1nc(C(=O)NCc2cc(-c3ccc(F)cc3F)on2)cs1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCOCC1 +CN(c1ccccc1)S(=O)(=O)c1cccc(NC(=O)C2CC2)c1 +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)NC1CCCC1(C)C +CN1CCN(Cc2cnc(C3CCC3)s2)C(C)(C)C1=O +Cc1onc(C=Cc2cccc(Br)c2)c1N +COc1ccc(CN2CC(C)OCC2c2ccccc2)cc1O +NS(=O)(=O)NCCS(=O)(=O)c1ccc(Br)cc1 +Cc1ccc(C(C)(O)CNC(=O)Nc2cccc(N(C)C)n2)o1 +CCCCCc1nnc(NC(=O)NC(C)(C)C)s1 +CSc1cccc(NC(=O)c2ccc(O)cc2)c1 +O=C(c1ccncc1)N1CCCc2cccc(OC(F)F)c21 +O=C(NC1CCc2c(Br)cccc21)C1CC=CC1 +CC(Cn1ccnc1)NC(=O)c1ccc(Cn2cncn2)cc1 +CN(C)c1cccc(C(=O)Nc2cccc(-c3ccn[nH]3)c2)c1 +CC1CCCCC1NC(=O)NCC(=O)NC(C)(C)C +CCOc1ccc(NS(=O)(=O)c2cn[nH]c2C)cc1 +Cc1ccc(NC(=O)NCc2ncoc2C)c(OCC2CCCO2)c1 +Cc1cccc(S(=O)(=O)N(C)CC(C)C#N)c1 +COc1ccnc(N2CCN(CC(=O)Nc3cccc(F)c3)CC2)n1 +CN(CCN1CCOCC1)C(=O)Nc1cnn(Cc2ccccc2)c1 +O=C(NCc1ccc(Cl)cc1Cl)c1cc(-c2ccco2)no1 +CC(C)Cn1c(-c2ccc(Cl)cc2)ccc(CO)c1=O +COCCC1(CNC(=O)c2cnc3ccc(C)cn23)CCCC1 +CN1CC(C(=O)N2CCC(C(=O)c3ccc(Cl)cc3)CC2)CC1=O +CCOC(=O)CN(C(C)C)S(=O)(=O)c1cn[nH]c1 +COc1ccccc1-c1nc(C(=O)NCCS(N)(=O)=O)cs1 +CC(Oc1ccc(F)c(F)c1)C(=O)NC1CCCC1 +Cc1cc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c2ccccc2n1 +O=C(c1ccc2c(c1)CCO2)N1CCC(Oc2ccccc2)CC1 +CC(Sc1ccccn1)C(=O)NC1C2CCOC2C1(C)C +COC(C)(C)C(=O)N1CCOc2c(O)cc(-c3cccnc3)cc2C1 +CNS(=O)(=O)c1cccc(S(=O)(=O)NCC(=O)N(C)C)c1 +N#Cc1cccc(NCC(=O)c2cccc(N)c2)c1 +CC(=O)c1ccc(OCC(=O)N2CCN(c3ccccc3)CC2)cc1 +CN(Cc1nccn1C(F)F)C(=O)c1ccc(Br)cc1 +CCC1CN(C)c2ccccc2CN1C(=O)CCc1ccncc1 +CN(C)c1oc(COc2ccccc2F)nc1C#N +N#Cc1ccccc1Cn1c(CO)nc2ccc(F)cc21 +COc1cccc(C(=O)OCC(=O)N2CCCC2)c1 +CC1CC(=O)c2cnc(NCc3ccccc3)nc2C1 +Cc1ccc2cccc(C(=O)N(C)c3ccccc3F)c2n1 +Cn1c(=O)c2c(-c3ccccc3Cl)n(CCO)cc2n(C)c1=O +CCOC(=O)C1=C(C)C(C(=O)NCCC(C)C)=NC1C +COc1cccc(-c2noc(-c3cccnc3)n2)c1 +Cc1c(Cl)cccc1OCC(=O)NCCNC(=O)c1cccnc1 +Cc1c(N)cccc1NC(=O)C(C)OCCC(C)C +Cc1nc(CNS(=O)(=O)c2ccc(-c3ccccc3)cc2)cs1 +CCC(C)n1c(-c2ccccc2OC)ccc(C#N)c1=O +O=C(c1ccc(-n2ccnn2)cc1)N1CCCC2CCCC21 +Cc1noc(C)c1C(=O)OCc1nc(-c2ccsc2)no1 +CCC1Oc2ccc(C(N)C(F)(F)F)cc2N(C)C1=O +CNC(=O)c1ccc(NC(=O)c2cc(Cl)c[nH]2)cc1Cl +CN(C)C(=O)c1cccc(NCC(=O)N(C)Cc2ccccc2)c1 +CC(C)n1cc(C(=O)N2CCC(C(=O)NCc3ccco3)CC2)cn1 +CC(C)(C)OC(=O)N1CCNC(c2ccccc2F)C1 +CC1CN(Cc2ccc(C(=O)NC(C)C(N)=O)cc2)CC(C)O1 +CCCC(=O)Nc1nnc(SCC(=O)Nc2nccs2)s1 +CCCc1noc(CCC(=O)N2CCOC(c3nc(CC)n[nH]3)C2)n1 +CCN(CC)C(=O)CCC(=O)N1CC(=O)Nc2ccccc21 +Cc1ccc(CNC(=O)c2cncc(Br)c2)n1C +Cc1ccc(Br)cc1S(=O)(=O)N1CCCCC1CO +Cc1ncc(CN(C)C(=O)NCCC(C)(C)C)s1 +Cn1cc(N2CCC3CN(S(C)(=O)=O)CC3C2=O)cn1 +Cc1cc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)oc1C +O=S(=O)(c1ccccc1)c1nnn2c1ncc1ccccc12 +CC(C)CNC(=O)c1ccc(F)cc1Br +COc1ccccc1N1CCN(C(=O)c2cc(=O)c(OC)co2)CC1 +CCCC(=O)NCC1COC2(CCC(C)CC2)O1 +CC1(CNC(=O)Cc2ccc(S(=O)(=O)C(F)F)cc2)CCCC1 +O=C1CCN(C(=O)NCCc2c[nH]c3ccc(Cl)cc23)CCN1 +COc1ccc2cc3c(nc2c1)N(C(=O)C(C)(C)C)CC3 +O=C(Cc1ccccn1)N(CCO)C1CCCCC1 +O=S1(=O)N=C(N2CCCCC2CO)c2ccccc21 +CCCNC(=O)c1ccc(N)c(OCC(N)=O)c1 +Cc1ccc2cccc(NC(=O)CCSc3ccccn3)c2n1 +CN(C(=O)Nc1ccccc1)n1cnc2ccsc2c1=O +CCCNC(=O)CCc1nc2cccnc2n1Cc1cccs1 +CCc1ccccc1NC(=O)CNC(=O)c1cc(C)sc1C +Cc1cc(Cl)ccc1NC(=O)NCc1ncn(C)n1 +CCC(C)(C)NC(=O)c1c(Br)c(C)nn1C +Cc1ccc(CCCC(=O)Nc2ccccc2-n2cnnn2)cc1 +Cc1nnc(C)c2c(C)n(-c3ccc(Cl)cc3)nc12 +CN(CCC(O)c1ccccc1)C(=O)CCc1ccnn1C +Cc1nc2cc(C(=O)N(C)CCn3cccn3)ccc2s1 +CC1Cc2cc(C(=O)N3CCCC(O)C3)ccc2N1S(C)(=O)=O +Cc1cc(C)cc(N(C)C(=O)c2cccc(-n3cnnn3)c2)c1 +CN(C(=O)C1CN(Cc2ccccc2)CCO1)c1ccc(Cl)cn1 +CCc1cc(C(C)O)c2c(c1)C(NC(=O)C(C)C)CCO2 +Cc1ccc(S(=O)(=O)Oc2nc(C)cc(C)n2)cc1 +CC1OCCC1S(=O)(=O)NCc1ccc(N)cc1Cl +CC(C)(NC(=O)c1ccco1)c1nc2c(c(C(N)=O)n1)OCCO2 +C=CCCC(=O)N1CCC(S(=O)(=O)c2ccc(OC)cc2)CC1 +OCCNc1nc(Nc2ccc(O)cc2)nc2ccccc12 +COc1cccc(C(=O)N2CCC3(CCN(C(C)=O)CC3)C2)c1 +Oc1cc2c(cc1Cl)CCNC2C(O)c1ccccc1 +O=C(CCNC(=O)c1ccc2ccccc2c1)NCC1CCCO1 +O=C(CCOc1ccccc1F)Nc1ccc(-n2ccnc2)c(F)c1 +O=C(CO)Nc1cccc(NC2Cc3ccccc3C2)c1 +COC(=O)CN(C(=O)c1n[nH]c(C)c1N)C(C)C +COC(=O)CCCC(c1ccc(O)cc1)c1ccc(O)cc1 +CCc1nnc(CNc2ccc(C)c(C(F)(F)F)c2)n1C +Cc1cccc(C(=O)NCCC(=O)Nc2ccc3c(c2)OCO3)c1 +CN(CC1CCCC1O)C(=O)NC(Cn1cccn1)c1ccccc1 +Cc1cc(C(=O)CN2CCOCC2)ccc1OCc1ccccc1 +Cc1cccc(Cl)c1NC(=O)c1cccc(C(=O)N(C)C)c1 +Cc1nc(CCC(=O)N2CCCC3(C2)C(=O)Nc2ccccc23)n[nH]1 +CN(CCc1ccccn1)C(=O)c1scnc1C1CC1 +Cc1ccccc1-n1ccnc1SCC(C#N)CCC#N +COC(=O)CCN(C(=O)C1CCCN(C(=O)C(C)(C)C)C1)C(C)C +CNC(=O)c1cccc(C(=O)NCC2CCC(C)(C)CC2)c1 +COc1ccc(C(O)C(C)NC(=O)C2CC2c2ccc(C)s2)cc1 +CC(c1ccc(S(C)(=O)=O)cc1)N(C)C(=O)Nc1ccccn1 +CCOc1ncccc1CNC(=O)c1cc(=O)[nH]c2ccccc12 +COc1ccc(NC(=O)c2cc3c(C)nn(CC(C)C)c3s2)cn1 +CN1CCN(C(=O)C2CCCN2c2ncccc2C#N)CC1 +CCc1ccc(C(C#N)N(C)C(=O)c2ccco2)cc1 +CC(=O)c1ccccc1NCC(=O)NCc1ccccc1 +O=C(N1CCc2ccccc21)C1(c2cccs2)CCOCC1 +COCCn1c(SCC(=O)N2CCCCC2C)nc2ccccc21 +Cc1ncsc1CCN1CCOC(c2nc(C(C)(C)C)n[nH]2)C1 +CS(=O)(=O)NC1CCCN(C(=O)CCOc2cccc(F)c2)C1 +CC(CC1CCCC1)C(=O)NCCc1nnc2ccccn12 +COCc1ccc(C(=O)N2CCCC2C(O)c2ccc(OC)cc2)o1 +Cc1cc(N)cc2c1N(C(=O)OC(C)(C)C)CC2(C)C +CN(C)C(=O)CSc1nnc(COc2ccc(C(C)(C)C)cc2)o1 +CC(C)(C)n1cc(NC(=O)COCC2CCCO2)cn1 +CCC(=O)Nc1sc2c(c1C(=O)Nc1ccc(OC)cc1)CCC2 +CC(C)(C)C(=O)CSc1ncnc2c1cnn2Cc1ccccc1 +CC(C)CCNC(=O)NC(C)C(=O)N1CCc2ccccc21 +CCN(CCO)C(=O)C(C)Oc1cccc(C(C)(C)C)c1 +CN(C)c1nc(-c2ccco2)nnc1-c1ccccc1 +CCC(C)NC(=O)c1cccc(CNC(=O)NCC(F)(F)F)c1 +COC(=O)Cn1cc(CCN2CCc3cc(F)ccc3C2)nn1 +Cc1nc(C2CCCN2C(=O)C2Cc3cc(Cl)ccc3O2)no1 +Cc1cccc(NCc2ccccc2C#N)c1C(N)=O +COCC(C)NC(=O)COc1cc(Cl)ccc1Cl +Cc1ccc(C)c(OCCSc2nccn2C)c1 +COc1ccc(Cl)cc1NC(=O)CN(C)C(=O)C1CC1 +CCOc1ccccc1OCC(=O)Nc1ccccc1N(C)C +CCCN(CCC)C(=O)CCc1c(C)nn(C)c1C +Fc1cc(Cl)cc2c1C(c1cncnc1)NCC2 +NC(=O)Nc1cccc(NC(=O)Cn2ncc3ccccc32)c1 +CNc1cc(-c2cc(C)c(OC)c(C)c2C)nc(C)n1 +CC(C)(C)NC(=O)Cc1nc(-c2ccccn2)n[nH]1 +COc1ccc(N(C)C(=O)c2ncn(-c3ccccc3)n2)c(OC)c1 +CCOC(=O)CCN1C(=O)C(C)(C)Cc2ccc(N)cc21 +COc1ccc(NC(=O)CCn2ncc3ccccc32)cc1Cl +CCCC1CN(C(=O)c2cccnc2OCC(F)(F)F)CCO1 +N#CCOc1ccc(NC(=O)C2Cc3ccccc3S2)cc1 +CCN(CC)C(=O)N1CCC(C(=O)NCc2cscn2)CC1 +CCOC(=O)COc1ccc(F)cc1-c1ccno1 +Cc1cccc(C(=O)N(C)Cc2nccn2C(F)F)c1 +CC(=O)Nc1cccc(NC(=O)CSc2ccccc2Cl)c1 +COC(=O)c1ccc2nc(NC(=O)c3cc(C)on3)sc2c1 +COc1ccccc1Oc1ccc(NC(=O)c2csnn2)cc1 +CN(C)c1cccc(-c2ccc(C(=O)N3CCOCC3)cn2)c1 +COCCCNC(=O)NCc1ccc(-n2cccn2)nc1 +COC(C(=O)N1CCOC(C(N)=O)C1)c1ccccc1 +Cc1ncsc1C(=O)N1CC(c2ccc(F)cc2)CC1C +Cc1cc2cc(NC(=O)c3csc(-c4ncccn4)n3)ccc2[nH]1 +COC(=O)C1(NC(=O)C2CCN(C)C(=O)C2)CCCC1 +CN(C)C(=O)c1cc(OC2CC2)c(Br)cn1 +COc1ccc(F)c(NCCn2nc3ccccn3c2=O)c1 +Nc1cc(-c2n[nH]c(-c3cccs3)n2)ccc1O +O=C(Cc1nnc(Nc2ccccc2)s1)NC1CC1 +COc1cccc(-c2nc3ccccc3c(=O)o2)c1 +CCCOc1ccc(-c2cc(CC#N)c(=O)n(CC)n2)cc1 +NC(=O)c1nn(-c2ccc(F)c(Cl)c2)c2c1CNCC2 +Cc1cnccc1CN(C)C(=O)c1oc2c(F)cccc2c1C +COc1ccc2c(c1)CC(C(=O)N1CCCC1)CO2 +C#CCCN1CCN(S(=O)(=O)Cc2ccccc2)CC1 +CC1CCCC(NC(=O)NCCCc2n[nH]c(N)c2C#N)C1C +CC(NC(=O)c1ccoc1)C(=O)Nc1ccc(C(N)=O)c(F)c1 +Cc1csc(C(=O)NCC#Cc2ccccc2N(C)C)c1 +CCc1cccc(NC(=O)C2CN(C(C)=O)c3ccccc3O2)c1 +Cc1ccc(NC(=O)c2ccc(Br)cc2)c(N)c1 +CC(C)(C)OC(=O)N1CCNC(c2ccccc2Br)C1 +O=C(CCc1cccnc1)Nc1cc(-c2cccs2)n[nH]1 +COCCN(CCC#N)Cc1cnc2ccc(C)cn12 +Cc1nc(C2CC3CCN(C(=O)c4cnccn4)CC3O2)no1 +COc1cc(C(=O)Nc2n[nH]c(-c3ccco3)n2)cc(Cl)c1OC +CCC(C)c1ccc(S(=O)(=O)NCc2nncn2CC)cc1 +CN(C)C(=O)c1ccccc1NCC(=O)N1CCCc2ccccc21 +COc1cccc(C(=O)NCCNC(=O)c2nonc2N)c1 +Cc1ccc(NC(=O)CNC(=O)c2ccccc2C)c(F)c1 +Cc1ccccc1C(C#N)CCC(=O)NCc1ccncc1 +Cc1cc(C)nc(N2CCN(CCc3ccccc3)CC2)n1 +CC(=O)c1ccc(Oc2cccc(N(C)C)c2)c(N)c1 +Cn1cc(CN2CCN(CC(O)c3cc(F)ccc3F)CC2)cn1 +CCCOC(=O)Cn1c(-c2ccccn2)ccc(C#N)c1=O +CCc1noc(CC)c1CNC(=O)NCCC(=O)N1CCCC1 +COCc1ccccc1NC(=O)CCC(=O)N1CCOCC1 +O=C(NCCCn1cnc2ccccc21)c1cc2ccccc2o1 +Cc1nc(C(C)(C)NC(=O)C(C)Oc2ccc(C#N)cc2)sc1C +CS(=O)(=O)c1c(Cl)c(F)nc(F)c1Cl +CN(Cc1ccoc1)C(=O)c1cn(CC2CCCCC2)nn1 +O=C1CCCN1CC(=O)N1CCCCC1CCc1ccc(O)cc1 +Cc1cc(NC(=O)NC2CCN(S(=O)(=O)C3CC3)CC2)no1 +CNS(=O)(=O)c1cccc(C(=O)NCC2CCC(C)(C)CC2)c1 +N#CC(C(=O)c1ccc(-n2ccnn2)cc1)c1nnc2n1CCCCC2 +O=C(Nc1cccc(-c2nc[nH]n2)c1)c1cc(-c2ccccc2F)on1 +CCOC(=O)c1ccc(CNC(=O)Cc2ccc(F)c(F)c2)o1 +OCc1c(-c2cccs2)nc2sc(-c3ccco3)nn12 +COc1ccc(CSc2nc3ccncc3[nH]2)cc1 +Cc1nc(CNC(=O)Cn2nc(C)c3ccccc3c2=O)c(C)s1 +Cc1cc(C(=O)NC2(C(N)=O)CC2)c(C)cc1Br +CCNc1nc(N2CCC(C(N)=O)CC2)nc2c1C(=O)CCC2 +O=C1CCCN1c1cccc(-c2csc(N3CCCCC3)n2)c1 +Cc1nc(C(=O)N2CCCC2c2ccc(F)c(F)c2)c(=O)[nH]c1C +CC1CC(=O)c2cc(C(=O)N3CCCCC3C)c(=O)[nH]c2C1 +CC(C)(C)C(=O)COC(=O)Cn1nc(C(N)=O)c2ccccc2c1=O +N#CCCn1c(=O)sc2cc(Br)ccc21 +O=C(Cc1ccc(F)c(F)c1)Oc1ccc2ccc(=O)oc2c1 +O=C(CCc1c[nH]c2ccccc12)Nc1cccc(-n2cnnn2)c1 +CC(=O)c1ccc(N2CCN(c3nn(C)c(=O)n(C)c3=O)CC2)cc1 +N#Cc1cccnc1NCCOC(=O)c1cnn(-c2ccccc2)c1 +COc1cccc(S(=O)(=O)CC(=O)Nc2ccccc2Cl)c1 +CC(=O)N(C)Cc1ccccc1NC(=O)C1CCCC1 +CCNS(=O)(=O)c1ccc(C(=O)N(C)CC(C)C)cc1 +CCC(NC(C)c1ccc(S(C)(=O)=O)c(F)c1)c1nccs1 +O=C(Cn1ccccc1=O)N=c1[nH]c2ccccc2[nH]1 +O=C(Cn1cc(F)c(=O)[nH]c1=O)C12CC3CC(CC(C3)C1)C2 +COc1ccc(NC(=O)Cc2cccs2)cc1OC(F)F +CCCNC(=O)c1c(C)nc(-c2ccco2)nc1SC +O=c1[nH]cccc1C1NCCc2c1ccc(Cl)c2Cl +Cc1ccsc1CN(C)C(C(=O)NC1CC1)c1ccccc1 +CCN(CCC#N)C(=O)Cc1c[nH]c2ccccc12 +CCS(=O)(=O)N(C)C1CCN(C(=O)c2ccc(C)c(C)c2)CC1 +CC(C)(C)c1noc(CCC(=O)N2CCCC(N3CCNC3=O)C2)n1 +c1cncc(-c2noc(-c3ccc(-c4ncn[nH]4)cc3)n2)c1 +CCOC(=O)CN1CCc2nc(NC(=O)OC)sc2C1 +CN(C)c1cc2c(nn1)CCN(C(=O)C1(C#N)CCCCC1)C2 +O=C(c1ccoc1)N1CCCC2(CC(OCc3ccccc3)CO2)C1 +Cc1ccc(CC(=O)Nc2ccc(-c3csnn3)cc2)cn1 +COc1ccc(CCNc2ccc(OC)c3nc(N)nn23)cc1 +CC(C)C(=O)NCCNC(=O)c1ccccc1C(F)(F)F +Cc1ccc(C(=O)NCCNc2cc(N3CCCC3)ncn2)cc1 +CC(C(=O)NCC1CCCO1)N1CCN(C(=O)C(C)(C)C)CC1 +c1ccc2c(c1)SCCCN2Cc1noc(-c2ccoc2)n1 +O=C(Nc1ccccc1N1CCCC1)c1ccc2c(c1)OCCO2 +CCc1ccc(C(O)CCc2nc(C)cs2)cc1 +COc1ccc(C(=O)Nc2cc3c(oc2=O)CCCC3=O)cc1 +NC(=O)N1CCCC(C(=O)NCCOc2ccc(F)cc2F)C1 +CN(CCc1ccncc1)C(=O)Nc1ccccc1Cl +CC1(C)C2CCC1(C)C(NC(=O)N(CCO)C1CC1)C2 +CC(C)C(NC(=O)Nc1ccccc1)C(=O)Nc1ccc(C#N)cc1 +O=C(NCc1ccc2c(c1)OCO2)c1ccc(-c2ccco2)[nH]c1=O +Cc1nc(-c2cc(C(=O)NC(C)C)c3ccccn23)cs1 +COc1ccc2c(C)cc(SCC(=O)NCc3ccco3)nc2c1 +Cc1ccccc1NC(=O)c1cc(=O)[nH]c2ccccc12 +Cc1ccc(C(C)NC(=O)c2ccc(-c3ccco3)[nH]c2=O)o1 +Cc1csc(C(C#N)C(=O)C(NC(=O)c2ccccc2)C(C)C)n1 +O=C(NCCc1ccccn1)c1ccc(S(=O)(=O)NC2CC2)cc1 +CC(=O)N1CCc2cc(C(=O)Nc3cc(C)cc4cccnc34)ccc21 +CCn1cc(NC(=O)NC2c3ccccc3CC2O)cn1 +CC(=O)N(CCc1ccccn1)Cc1ccc(F)cc1 +CCOC(=O)CNS(=O)(=O)c1ccc(C(F)(F)F)cc1 +CC(C)(O)CNC(=O)c1ccc(-n2ccnn2)cc1 +O=S(=O)(NCc1nnc2ccccn12)c1c(F)cccc1F +CC(CN1CCCC1=O)NC(=O)c1ccc(=O)[nH]c1 +CC(C)(CO)NC(=O)c1ccc(-c2ccccc2)o1 +CN(C)C(=O)c1ccccc1NCC(=O)N1CCNC(=O)C1 +Cc1noc(C)c1C(=O)OCc1cc(Cl)c2c(c1)OCO2 +COCc1ccc(CN2CCOC3CCCCC32)o1 +O=C(Cn1c(=O)cnc2ccccc21)N1CCCC(n2cccn2)C1 +O=C(Oc1ccc(Br)cc1)c1cccnc1 +O=C(Cc1ccsc1)Nc1ccc(Br)cc1 +CCOC(=O)c1sc(NC(=O)NCc2cnn(C)c2C)cc1C +CCOc1ccc(C2(Cc3cccs3)NC(N)=NC2=O)cc1 +CN(C)C(=O)c1ccnc(NCc2cn(C)nc2C(C)(C)C)c1 +COc1ccc(C(O)CNS(=O)(=O)N(C)C)cc1Cl +O=C(NCCCc1ccccc1)c1cnc2sccn2c1=O +Cc1nc2cc(NC(=O)C3CC4CCC3O4)ccc2o1 +CNc1ccc(NS(=O)(=O)c2cccc(C)c2)cc1F +COc1ccc(-c2cc(C(=O)NCC(C)C)n(C)n2)cc1 +COC(=O)c1ccc(COC(=O)Cc2n[nH]c(=O)c3ccccc23)o1 +COc1ccc(-c2nnn(-c3ccccc3O)c2N)cc1F +C=CCc1cc(CNS(C)(=O)=O)cc(OC)c1OC +CCC(C)Nc1ncnc(Nc2ncccc2C)c1N +O=C1NCC(C(=O)N2CCC3(CCC(=O)N(CCO)C3)CC2)N1 +O=C(NCc1c(F)cccc1Cl)c1cc2cccn2cn1 +CCCC1CCC(NC(=O)NC2CCN(C(C)=O)CC2)CC1 +Cc1nn(C)c(C(=O)NC2CC2)c1Br +COc1ccccc1CCC(=O)N1CCCC1c1c(C)nn(C)c1C +CCOC(=O)c1cc(C(=O)Nc2sc3c(c2C#N)CCC3)n(C)n1 +COC(C)(C)C(=O)NC1CCCc2cn(C3CCCC3)nc21 +Cc1cc(Br)cnc1NCC(O)C1CCOCC1 +Cc1nc(C2CCCC2)nn1Cc1ccc(F)cc1 +CC(C)c1noc(CCNC(=O)c2ccccc2OC(F)F)n1 +CCc1nc2n(n1)CCCC2NC(=O)c1ccccc1Cl +CCC1COCCN1Cc1cc(OC)cc2c1OC(C)C2 +Cc1cnc(N2CCC3(C2)CN(c2cnn(C)c2)C(=O)CN3C)nc1 +O=C(NCc1ccc(O)cc1)Nc1cccc(N2CCCCC2)c1 +CCOC(=O)C1=C(C)N=C(C)C1S(=O)(=O)N1CCc2ccccc21 +Cc1cc(N)cc(S(=O)(=O)NCC(C)O)c1C +CCOc1ccc(N2Cc3ncccc3C2=O)cc1 +CC(C)CCNC(=O)C(C)N1CCN(C(=O)CC(F)(F)F)CC1 +COCCCn1ccc(NC(=O)C2COc3ccc(F)cc3C2)n1 +COC(=O)C1C2CC1CN(C(=O)OC(C)(C)C)C2 +Cc1ccc(-c2ncco2)cc1NC(=O)C(C)C1CCOCC1 +CCCC(=O)N1CCC(C(=O)Nc2ccc(OCC)cc2)CC1 +Cc1ccc(-n2nnnc2SCc2cccc(-n3cccn3)c2)cc1 +CCCn1nc(C(C)(C)C)cc(C(C)(C)O)c1=O +CCCCCNC(=O)CC(C#N)c1ccccc1F +CCCOc1ncccc1CNC(=O)Nc1cn[nH]c1 +Cc1csc(NC(=O)NCc2nc3ccccc3s2)n1 +COc1ccc(N)cc1NC(=O)c1ccc(OCC(C)C)cc1 +COC(=O)CC(C)c1ccc(OC)c(Br)c1 +CCCOc1ccc(C(C)Nc2ncnc3c2cnn3C)cc1OC +O=C(Nc1ccnn1CC1CCOC1)C1CC1c1ccc(Cl)cc1 +COc1cccn(Cc2cc(F)c(F)cc2F)c1=O +CC(C)CCCNC(=O)c1cc(S(N)(=O)=O)ccc1Cl +CCc1nnc(NC(=O)CNC(=O)c2cc(C)cc(C)c2)s1 +Nc1ccc(-n2nnc3ccccc32)c2nonc12 +CCOc1ccccc1S(=O)(=O)NCC(O)c1sccc1C +Cn1ccnc1SC(C(N)=O)c1ccc(Br)cc1 +CCCOc1ccccc1NC(=O)NC(C)C(=O)NC(C)(C)C +Cc1ccc(N2C(=O)Nc3ccccc3S2(=O)=O)cc1 +CCC(=O)N(CCOC)c1nnc(-c2ccc(C)cc2)s1 +CC1CC(N2CCN(Cc3cccc(O)c3)CC2)C(=O)O1 +Cc1ccccc1OCCN(C)C(=O)c1cccc2cn[nH]c12 +CC1CN(C(=O)Cc2cccc3cccnc23)CC(C)(C)O1 +COc1ccc(-c2n[nH]c(-c3ccncc3)n2)cc1 +COc1ccc(CC(=O)Nc2ccccc2C(F)(F)F)cc1OC +Cc1ccc(C(=O)Nc2ccc(Cl)cc2C(N)=O)c(C)n1 +O=C(NCCCO)c1ccccc1S(=O)(=O)N1CCCCC1 +COc1ccc(C(=O)Cc2ccc3c(c2)OCCO3)c(O)c1 +CC(C)(CNC(=O)c1csnn1)N1CCOCC1 +CC(=O)NC(CC(=O)NCc1cccs1)c1ccccc1 +O=C(NCCO)c1cccc(OCc2ccn(-c3ccccc3)n2)c1 +COc1cc(C2NC(N)=Nc3nc4ccccc4n32)cc2c1OCO2 +COc1ccc(Cl)c(NCCn2nc3ccccn3c2=O)c1 +CC(=O)c1ccccc1NC(=O)CNc1ccc(F)c(C(N)=O)c1 +COc1cccc(F)c1C1NCCc2cc(O)ccc21 +CSc1c(Br)cncc1OC1CC1 +O=C(Nc1cc(Br)cc(Cl)c1O)c1ccon1 +Cc1c(NC(=O)NCCSc2nnnn2C)cc2[nH]cnc2c1C +Cc1ccsc1C(=O)N1CCc2onc(-c3ccncc3)c2C1 +Cc1ccc2c(c1Cl)CCNC2c1ccnnc1 +CCOC(=O)C1(NC(=O)C2CC(=O)N(C3CCCC3)C2)CCCC1 +CSc1sc(NC(=O)c2cccc(-n3cnnn3)c2)nc1C +COC(=O)C1(N(C)C(=O)Cc2c[nH]c3ccc(F)cc23)CCCCC1 +CCOc1ccc(N2CC(C(=O)N3CCC(C)CC3)CC2=O)cc1 +C=C(C)Cn1c(CCNC(=O)C2CCCO2)nc2ccccc21 +O=C(NCCNS(=O)(=O)c1cccnc1)c1ccccc1F +CCNC(=O)CNC(=O)Nc1ccc2c(c1)CCC2 +COc1cc2c(cc1NC(=O)Cn1ccccc1=O)oc1ccccc12 +CCC(=O)Nc1ccc(N2CCC(C)CC2)cc1N +Cn1cc(CCC(=O)Nc2ccc(NC(=O)OC(C)(C)C)nc2)cn1 +CC(C)(C)OC(=O)N1CCC(Nc2cccc(F)c2N)CC1 +CC(C)(C)c1ccc(C(=O)NCCCn2cccn2)cc1 +CCS(=O)(=O)N(C)CCCNC(=O)c1ccc2cc[nH]c2c1 +OC(CNc1ncnc2[nH]cnc12)c1ccc(Cl)cc1 +CN(Cc1ccccc1)c1ncnc2sccc12 +Cc1cc(C(=O)N2CCc3ccc(Cl)cc3C2)oc1C +COc1ccc(Cl)cc1NCc1nccs1 +COc1ccc(Cl)cc1NC(=O)NCCC(O)c1ccccc1 +O=S1(=O)N=CNc2ccc(S(=O)(=O)NC3CCCC3)cc21 +CCc1onc(C)c1NC(=O)CCc1cc(F)ccc1F +Cc1ccc(N2CC3(CCN(C(=O)c4ccccn4)C3)CC2=O)cc1 +NC(=O)C1CCCN(C(=O)c2ccc(-c3ccc(F)cc3)s2)C1 +CNC(=O)NCC(C)Oc1cccc(Br)c1 +O=C(NC1CC1)C(NCc1ccco1)c1ccccc1 +OCCc1cnn(Cc2cc(Br)ccc2F)c1 +CC(O)Cn1c(NC2CCCCC2)nc2c1c(=O)[nH]c(=O)n2C +O=C(NCc1nnc(-c2ccccc2)s1)N1CCOCC1C1CC1 +Cc1nc(C(F)(F)F)ccc1C(=O)N1CCC(n2cccc2)CC1 +COc1ccc(CCC(=O)N2CCN(Cc3cccn3C)CC2)cc1 +CN(Cc1ccccc1)C(=O)CNC(=O)c1cc2ccoc2s1 +CCc1c(C(=O)Nc2ncc(C)s2)cnn1-c1ccc(F)cc1 +COCC(=O)N1CC2CCC(C1)N(Cc1c(C)noc1C)C2=O +Cc1nn(C)c(C)c1NC(=O)C1(C)Oc2ccc(Cl)cc2NC1=O +O=C(c1cc(-c2cc[nH]n2)n2ccccc12)N1CCCCC1 +CCNC(=O)CCNS(=O)(=O)c1ccc(F)cc1 +Cc1cccc(COCC2CCCC23CN(C(N)=O)CCO3)n1 +COCC(C)NC(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +CC(C)CCNC(=O)c1ccc(-n2cnnn2)cc1 +Cc1cc2cc(NC(=O)Cn3cncn3)ccc2o1 +O=S(=O)(Cc1ccc(Cl)cc1)Nc1ccncc1 +Cc1ccc(CNC(=O)c2ccccc2S(C)(=O)=O)cc1F +O=C(NCCc1ccccc1)C1CCCN1C(=O)C1CC1 +Cc1nc(N2CCN(c3ccc(F)cc3)CC2)nc2c1C(=O)CCC2 +Cc1cc(=O)oc2cc(OC(=O)CCn3c(C)csc3=O)ccc12 +CCC(CO)Nc1nc2c(c(=O)n(C)c(=O)n2C)n1C +Cc1nnc(-n2nnc(CO)c2CC(C)C)s1 +CCc1ccccc1C(=O)NCC(C)(C)c1ccncc1 +Cc1cccnc1C(NC(=O)NCc1ncn(C)n1)C(C)C +CCc1nnc(NC(=O)NCCCN2CCCCCC2=O)s1 +COc1cc(C)c(NC(=O)COc2ccc3c(c2)OCO3)cc1C +CCOC(=O)C1=C(CN(C)CC)NC(=O)NC1c1ccco1 +Cc1ccc(CC2Oc3cc(N)ccc3NC2=O)cc1C +COc1ccccc1C#CCNC(=O)CSc1ccc(F)cc1 +CC1(CNC(=O)NC2CCN(C(=O)c3cnccn3)CC2)CCCC1 +CCC(CC)c1nnc(NC(=O)c2cn(C)nc2C(C)(C)C)s1 +CCC(=O)Nc1cccc(OCC(=O)Nc2ccc(F)cc2)c1 +Cc1cccnc1CN1CCN(C(=O)c2cnn(C(C)C)c2)CC1 +O=C(CCc1ccccn1)NC1CC1c1cccc(C(F)(F)F)c1 +COc1cccc2c(=O)c(NC(=O)NCc3cccc(F)c3)c[nH]c12 +Cc1cnc(C(=O)Nc2c(C)cnn2Cc2cc(F)ccc2F)cn1 +Cc1cccc2c(=O)n(Cc3ccc(C#N)cc3)ccc12 +CNC(=O)c1cc(Cl)ccc1NCc1nc(C)no1 +CC(=O)Nc1nnc(Cc2nc3ccccc3n2C(C)=O)s1 +Cc1ncsc1C(=O)N1CCCN(Cc2nccn2C)CC1 +Cc1ccc(N2CC3OCC(=O)N(Cc4csc(C)n4)C3C2)nn1 +COc1cc(NC(=O)c2c(Cl)cnn2C)c(OC)cc1Cl +COc1ccc(NC(=O)c2cc3ccc4cccnc4c3[nH]2)c(OC)c1 +CCN(CCC(F)(F)F)C(=O)c1[nH]nc(C2CC2)c1Cl +COc1ccc(-c2cc3cccnc3[nH]c2=O)c(OC)c1 +Cn1c(C(=O)NCc2ccco2)cc2c(F)cccc21 +O=C(NCc1ccccc1F)C1COc2ccccc2O1 +CCn1c(SCC(=O)Nc2ncc(C)s2)nc2ccccc21 +CCS(=O)(=O)N1CC(c2nc(-c3cccnc3)no2)C1 +CC(=O)Nc1nnc(SCC(=O)NC2CCCCC2)s1 +CCC(COC)NC(=O)NC(CC)c1cc(F)ccc1F +CCCCCNC(=O)c1cccc(C)c1NC(=O)c1ccccc1F +COc1cccc(OCCCSc2nc(N)cc(=O)[nH]2)c1 +COc1ccc(CC(=O)N2CCc3ccc(Cl)cc3C2)cc1OC +CC(=O)Nc1cccc(NCC2CC3C=CC2C3)c1 +COC(=O)C(O)(c1ccc(O)c(Cl)c1)C(F)(F)F +CCCCS(=O)(=O)Nc1cccc2c1CCCN2 +CCNC(=O)c1ccc(NC(=O)C2CCCN2C(=O)C2CC2)cc1 +COc1ccc(OC)c(S(=O)(=O)n2ccnc2)c1 +COc1ccc(SCC(=O)Nc2ccn(C)n2)cc1 +CCc1onc(C)c1NC(=O)N(C1CC1)C(C)C1CC1 +Cc1cnc(=O)n(Cc2ccccc2C#CCO)c1 +COC(=O)C1(NS(=O)(=O)c2ccccc2)CCCC1 +Cc1cc(C)nc(SCC(=O)Nc2cc(C)nn2C)n1 +CC(Sc1nnc(-c2ccncc2)o1)C(=O)N(C)c1ccccc1 +CC(=O)N1CCC(=O)c2cccc(C(F)(F)F)c21 +CC(O)CCNc1ccc(S(=O)(=O)N2CCCC2)cn1 +COc1ccc(O)c(C(=O)NCC(=O)NCc2ccco2)c1 +c1cnn(-c2ccc(CN3CCOC(C4CCCO4)C3)cc2)c1 +Cc1nc(-c2ccc(C(=O)N3CCc4ccccc43)cc2)cs1 +CCOc1ccc(C(=O)N2CCN(C(C)=O)CC2)cc1OCC +COc1ccc(NC(=O)NCC2CCCC2O)c(Br)c1 +O=C1CCc2cc(NC(=O)Nc3ccccn3)ccc2N1 +CC(NC(=O)c1ccco1)C(=O)NCCc1nc2c(s1)CCCC2 +N#CCn1c(CCOc2ccccc2)nc2cc(F)c(F)cc21 +O=C(CC1CCCC1)N1CCCC(c2nnc(C(F)(F)F)o2)C1 +Cc1nn(C)cc1C(=O)N1c2ccccc2N(C)CCC1C +COc1ccc(-n2nnc(CO)c2-c2cccs2)cc1 +Cc1n[nH]c(C)c1CCC(=O)N1CCC(CCN2CCCC2=O)CC1 +COCCNS(=O)(=O)c1cc(OC)c(C)cc1C +COc1ccc(-c2nnc(N3CCC(C(=O)NC4CC4)CC3)o2)cc1 +N#CCSc1nnc(COc2ccc(Cl)cc2Cl)o1 +Fc1ccc(-c2csc(NCC3CCCO3)n2)cc1F +O=C(CSc1ncn[nH]1)NC1CCCc2ccccc21 +COc1c(OC)c(O)c2c(=O)c(O)c(-c3ccccc3)oc2c1OC +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc3c(c2)OCO3)c1C +Cc1ccc(C(=O)Nc2ccc3c(c2)C(C)(C)C(=O)N3C)s1 +CC(C)N(C(=O)CN(C)S(=O)(=O)c1cccnc1)C1CCC1 +Cc1cc(O)ccc1NC(=O)c1n[nH]c2ccccc12 +CCCNC(=O)c1cnc(-c2ccc(Cl)cc2)nc1N +N#Cc1cccc(NC(=O)CN2CCc3cc(F)ccc3C2)c1 +CC(CNC(=O)COc1ccc2ccc(=O)oc2c1)c1cccs1 +Cc1cccc(COc2cccc(C(=O)Nc3nc[nH]n3)c2)c1 +O=C(CCOc1ccc(Cl)cc1)N1CCN(c2cnccn2)CC1 +Cc1cccc(C)c1N(C)C(=O)c1ccccc1N +O=C(NCc1cc(F)ccc1Br)c1c[nH]nn1 +CCOc1ccccc1N1CCN(C(=O)c2cccc(C)c2)CC1 +CCOC(=O)c1c(C)c(C(=O)Nc2ccc(C)c(F)c2)c(C)n1C +CC(C)c1ccc(NC(=O)c2nc[nH]c2-c2cccnc2)cc1 +N#CC1(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)CCCC1 +CC1CCCC(N2CN=C(NS(C)(=O)=O)NC2)C1C +Cc1nc(C2CCCN2C(=O)c2ccc(N3CCNC3=O)cc2)no1 +CCC(C)NC(=O)COc1cccc(Br)c1 +CCc1c(C)nn(C)c1NC(=O)NCC1(Cn2nc(C)cc2C)CC1 +CCOc1cc(CNc2ccccc2OCC)ccc1O +CC(Sc1ccccc1F)C(=O)N1CCCC1 +CC(OC(=O)c1ccc2c(c1)NC(=O)CS2)C1CC1 +CCC(C)Oc1ccccc1-c1cn[nH]c(=O)c1CO +CC(C)(C)NS(=O)(=O)c1ccc(C(=O)Oc2ccccc2F)o1 +Cc1cc(=O)n2nc(C)c(COc3ccccc3)c2[nH]1 +CCNS(=O)(=O)CCNC(=O)Cc1c[nH]c2c(C)cccc12 +CCCN(CC1CC1)C(=O)NCc1ccc(-n2ccnc2C)c(F)c1 +COC(=O)C(NC(=O)NC1CCC(C)CC1)C(C)C +CCn1nccc1C1CCCN1C(=O)c1c(Cl)cnn1CC +CC1CN(S(=O)(=O)c2cccc(C(=O)N(C)C)c2)CC(C)O1 +Cc1nc(-c2ccsc2)sc1C(=O)Nc1ccccc1O +CCCn1nnnc1SCC(=O)c1ccc(NC(C)=O)cc1 +CS(=O)(=O)N1CCN(Cc2nnnn2-c2ccc(F)cc2)CC1 +Nc1ccc(NS(=O)(=O)c2ccccc2)c(Cl)c1 +CC(Cc1ccc(Cl)cc1)N(C)Cc1nnc(C2CCC2)o1 +CCCc1noc(CCC(=O)N(C)Cc2cccs2)n1 +CC(=O)c1sc(NC(=O)Cc2ccc(Cl)cc2)nc1C +Cc1cccc(-n2ncc3c(N4CCOCC4)ncnc32)c1 +CCOc1ccccc1C(=O)Nc1cccc(-n2cnnn2)c1 +Cn1cccc1C1CCCCCN1C(=O)CCn1cncn1 +CCCCOc1cc(NCc2ccco2)nc(C)n1 +O=C(CCNC(=O)Nc1cc(F)ccc1Cl)NC1CCCC1 +CCc1ccccc1OCC(=O)N1CCN(Cc2cccnc2)CC1 +Cc1cc(NC(=O)COC(c2ccccc2)c2ccccc2)no1 +O=C(c1cc2ccccc2o1)N1CCc2cc(F)ccc2C1 +Cc1nc(CN2CCN(c3nccs3)CC2)cs1 +COC(=O)CCNC(=O)CCc1ccccc1Cl +Cc1c(NC(=O)C2CCCCC2)c(C(=O)N(C)C)nn1C +COc1cccc(NC(=O)c2cn(CC(O)c3ccccc3)nn2)c1 +NC(=O)c1ccc(-n2nnc(CO)c2C2CCCO2)cc1 +Cc1cccc(COc2cccc3c2CCC3O)c1 +CC(C)C(C)(C#N)NC(=O)COc1ccc(C#N)c(F)c1 +Cc1ncsc1CCCn1ccnc1-c1ccc(C(N)=O)cc1 +Cc1cccc(C)c1OCC(=O)N1CCCC1C(N)=O +CCNC(=O)c1ccc(NC(=O)N2CCN(C(=O)OCC)CC2)cc1 +CC1CCCN(C(=O)CNC2(c3cccc(F)c3)CC2)C1 +COc1cccc(C(O)C(=O)NC(c2ccn(C)c2)C(F)(F)F)c1 +Cc1ccc(OC(C)C(=O)NCC(O)c2ccccc2Cl)cc1 +CC(C)NC(=O)C1CN(Cc2nccs2)CC2OCCC21 +O=C(CSc1nnc(-c2cccnc2)o1)Nc1ccccc1Cl +COc1ccccc1OCC(=O)NCc1ccccc1 +Cn1nnnc1SCCC(=O)Nc1ccccc1C(C)(C)C +CC1Cc2ccccc2N1C(=O)COc1ccccc1F +CN1C(=O)Cc2cc(-c3csc4nnc(N)n34)ccc21 +CCN(C(=O)CSc1nncn1C(C)C)C1CC1 +COc1cc(-c2ccnc3nc(C(C)C)nn23)cc(OC)c1OC +COC(=O)c1ccc(NC(=O)C2CC(=O)N(CC(F)(F)F)C2)cc1 +CCc1ccc(OCC(=O)Oc2cccc(C(=O)NC)c2)cc1 +Cc1occc1C(=O)N1CCN(C(C#N)c2ccccc2)CC1 +COc1cc(C)sc1C(=O)Nc1ccc(OCCC(N)=O)cc1 +O=C(CN1CCN(Cc2ccc(F)cc2)C1=O)NCc1cccs1 +Cc1cc(CN(C)C(=O)NCc2c(C)noc2C)no1 +COC(=O)c1ccc(C(C)Sc2nc(C)cs2)o1 +O=C(CCNC(=O)c1ccco1)Nc1cccc(CO)c1 +COC(=O)c1ccc(Cn2ccnc2-c2cccc(NC(C)=O)c2)cc1 +CCCNC(=O)CNC(=O)N1CCN(c2cccc(C)c2C)CC1 +CCN(CCC#N)C(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 +O=C(NCCS(=O)(=O)N1CCCC1)Nc1cccc2c1CCC2 +CC(C)N1CC(C(=O)NCc2ccncc2)CC1=O +CCN(CC1CCCO1)C(=O)Nc1ccc(F)cc1OCC1CC1 +CCS(=O)(=O)NCCNC(=O)c1c(C)oc(C)c1C +CCc1nn(C)c(CC)c1C(=O)N1CCN(C)CC1 +CC(C)n1cc(CN(Cc2ccccc2)Cc2nccs2)cn1 +Cc1nnc(N2CCCC2C(=O)NCC(F)(F)F)c(C#N)c1C +O=C(Cc1ccc(-n2cccn2)cc1)NC1CCCc2occc21 +CCc1nc(-c2ccc(C(=O)Nc3cc(F)ccc3OC)cc2)n[nH]1 +COc1cccc(-n2c(=O)[nH]c3c(C(N)=O)ncnc32)c1 +Cc1cc(S(=O)(=O)N(C)C)cc(NCc2c(C)noc2C)c1C +CC(=O)NC(C(=O)N1CCC(C(=O)N2CCCC2)CC1)C(C)C +Cc1noc2ncc(C(=O)N3CCc4ccc(Cl)cc4C3)cc12 +Cc1cc(Br)cc(C)c1NCC(=O)N1CCOCC1 +Cc1cc(C(=O)NCc2nc(C)sc2C)c(C)s1 +COc1cccc(OCCNC(=O)NCc2cccs2)c1 +COc1cc(=O)[nH]c(SC(C)C(=O)Nc2ccc(C)cc2)n1 +COCCN(CCOC)C(=O)c1ccc(N)nn1 +CCCNC(=O)Nc1cccc(OCC(=O)NC2CC2)c1 +N#Cc1ccc(C(=O)NCCc2ccccc2)cc1 +Cc1cccc(-c2nnc(Cn3cnc(C4CCC4)cc3=O)o2)c1 +CC1CCCC(OC(=O)c2ccc(C(N)=O)cc2)C1 +Cc1ccc2cc(-c3noc(-c4cccs4)n3)c(=O)[nH]c2c1 +CC1(C)CS(=O)(=O)N(c2ccc3c(c2)OCO3)C1=O +COc1ccc(-n2cc(CNC(=O)Nc3nc(C)cs3)nn2)cc1 +CCSc1nnc(N)n1Cc1ccc(Cl)c(Cl)c1 +C=CCOC1C2CCC1N(C(=O)c1cc(F)c(F)cc1C)CCO2 +COC(=O)c1cnn2cccc(Br)c12 +CC(=O)N1CCc2cc(C(=O)Nc3cn[nH]c3)ccc21 +CC(C)c1nnc(CN2C(=O)OCC2C(C)C)o1 +N#Cc1ccc(CNC(=O)NCCNC(=O)C2CCCC2)c(F)c1 +COc1ccc(S(=O)(=O)CC(=O)Nc2cccc(Cl)c2)cc1 +C=C(C)CN(CC)C(=O)CN(C)S(=O)(=O)c1c(C)noc1C +CC(=O)c1ccc(OCC(=O)NC(C)c2ccc(F)cc2F)cc1 +CN(CCn1ccc2ccccc21)S(=O)(=O)NCc1ccccc1 +CN(C)C(=O)C(c1ccccc1)N1CCC(c2ccn[nH]2)CC1 +CC(C)CN(C(=O)CCc1ccccc1N)C1CC1 +COc1ccc(NC(=O)CC2C(=O)Nc3nc(C)nn32)cc1 +COc1cc(C(C)Nc2cc(C3CC3)ncn2)cc(OC)c1OC +Cn1ncc2c(N3CCCC(O)C3)nc(CCc3ccccc3)nc21 +CCn1cc(C)c(-c2ccccc2OC)c(C#N)c1=O +Cc1cnc2c(c1)nc(-c1ccc(F)cc1)n2CCCO +O=C(Cn1cnc2ccccc21)N(Cc1ccco1)Cc1ccco1 +C=CCOC(=O)c1ccc(-c2ccc(N)cc2OC)o1 +CC(NCc1nnc(C2CC2)n1C)c1cccc(-n2cccn2)c1 +CCS(=O)(=O)N1CCC2(CC(Nc3ncc(F)cn3)CO2)C1 +CC(C(N)=O)n1ccnc1Cc1ccc(C(C)(C)C)cc1 +Cc1ccc(Br)cc1S(N)(=O)=O +O=C(Cc1ccc[nH]1)Nc1ccc(-c2cn3cccnc3n2)cc1 +CCC(CC)(CNC(=O)c1n[nH]c(=O)[nH]1)c1ccc(Cl)cc1 +COC(=O)C1NS(=O)(=O)c2cscc2C1=O +O=C(N=c1[nH]c2ccccc2[nH]1)c1ccc(-n2cccc2)cc1 +CCC(C)(C)C(=O)N(C)Cc1cc(C#CCO)cs1 +Cc1cc(=O)c(C(=O)NC2CC2)nn1-c1cccc(C(F)(F)F)c1 +CNC(=O)C1(C)CN(C(=O)c2ccccc2)CCO1 +CN(CCC(O)c1ccc2c(c1)OCO2)c1ccccc1 +COC(=O)C(C)(C)NC(=O)C(C)Cc1cccc(F)c1 +Cc1cnc(NC(=O)C(C)Oc2ccc(Cl)cc2C)s1 +Cc1nc(C)c(CC(=O)N2CCN(c3ccccc3)CC2)c(=O)[nH]1 +Fc1ccc(Br)c(CNCCc2nnc3ccccn23)c1 +Cc1cc(C)c(NC(=O)c2cccc(S(C)(=O)=O)c2)c(C)n1 +Cc1cccn2c(=O)cc(COC(=O)c3ccc(CO)cc3)nc12 +O=C(NCCCO)C1(c2ccc(Cl)cc2)CCC1 +Cc1noc(C)c1CC(=O)NCc1cccc(F)c1 +CCCc1ccc(S(=O)(=O)N(C)C(C)C)cc1 +CN1CCN(C(=O)CSc2nnc(N)n2C)CC1 +CCOC(=O)c1noc(C(=O)Nc2ccccc2)c1N +COc1ccc2c(CN3CCc4cc(F)ccc4C3)cc(=O)oc2c1 +O=C(c1nc(-c2cnccn2)no1)N1CCC2(CC1)OCCO2 +COCCN1CCN(S(=O)(=O)N2CCC(C(C)(C)C)CC2)CC1 +CN1CCNC(c2ccc(S(C)(=O)=O)cc2)C1=O +O=C(Nc1nccs1)c1cccc(NC(=O)c2cccs2)c1 +CCc1nc(CNc2cc(NC(=O)OC(C)(C)C)ccc2F)no1 +CCOc1ccccc1C(=O)Nc1cccc(-c2nnnn2C)c1 +c1ccc(Cn2cnnc2C2CCCN(Cc3cccnc3)C2)cc1 +Cc1nc2ccc(NC(=O)c3cnn(C(C)(C)C)c3)cc2s1 +O=C(Nc1c(F)c(F)c(F)c(F)c1F)c1ccccc1F +O=C(c1cnc2ccccn2c1=O)N1CCCc2ccccc21 +CNC(=O)Cc1nc(CNc2cccc(-c3cccs3)c2)cs1 +Cc1ccc(CC(=O)N(C)CC(=O)Nc2ccccc2)cn1 +CCC(C)NC(=O)C(C)NC(=O)Nc1ccc(-n2nccn2)cc1 +COc1ccccc1CNC(=O)Cn1ccc2cccc(OC)c21 +O=C(NCCc1ccncc1)c1csc(-n2cccc2)n1 +Cc1ccc(NC(=O)NC(C(N)=O)C(C)(C)C)cc1OC(F)F +CCCNC(=O)c1nnn(-c2ccc(Cl)cc2)c1CCC +COc1ccc(CNC(=O)CNC(=O)c2scnc2C2CC2)cc1 +Cc1nc(CCNc2nc(N(C)C)cc(C(F)(F)F)n2)cs1 +CCOC(=O)C1(NC(=O)Cc2ccc(-n3cnnn3)cc2)CCCC1 +COC1CCN(C(=O)c2csc(-c3ccccc3F)n2)CC1 +CCC(C)Oc1cccc(NC(=O)N(C)CCOC)c1 +Cc1ccc(OCCC(=O)OCc2nc(C)no2)c(C)c1 +CCn1ncc2c1C(COC)CN(C(=O)c1ccco1)C2 +Cc1ccc(NC(=O)CCn2cc(C)cn2)c(OCC2CCCO2)c1 +CC1CCCC(OC(=O)CNC(=O)CC(C)(C)C)C1 +Cn1c(C(=O)N2CCOCC2C2CC2)c(Cl)c2ccccc21 +O=C(Nc1cccc(C(=O)N2CCCC2)c1)C1CC2C=CC1C2 +COC(=O)c1ccccc1NC(=O)c1cnc(C)cn1 +COc1ccc(C(N)C(F)(F)F)c2ccccc12 +Cc1cccc(C)c1CNc1[nH]c(C)c(C)c1C#N +Nc1nc(N2CCCC(N3CCNC3=O)C2)nc2ccccc12 +CC(C)Cc1nnc(C(C)Sc2cccc3cccnc23)o1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2nc3ccccc3s2)c1 +Cc1ccc(N)cc1NC(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +O=C(NCc1nncn1C1CCCCC1)C1COc2ccccc2O1 +CCc1cc2c(NCC3CCCO3)nc(-c3cccnc3)nc2s1 +COCCCNC(=O)C1CC(=O)N(Cc2ccco2)C1 +CC(N(C)C(=O)NCc1ncn(C)n1)C1(C)CC1 +O=C(NCc1cccnc1-n1ccnc1)c1ccc(-n2cnnc2)nc1 +Cc1noc(COCC(=O)Nc2cc(Cl)c(Cl)cn2)n1 +O=C(CN1C(=O)CCCc2ccccc21)NCCc1ccco1 +CC(C)=CC(=O)OCC(=O)c1ccc(N(C)S(C)(=O)=O)cc1 +CCOC1CCCN(C(=O)c2cc(C3CC3)[nH]n2)C1 +Cn1cccc1CN(C(=O)c1cccs1)C1CC1 +CC1(C)Oc2cc(Br)ccc2NC1=O +CCN(CC)C(=O)CCNS(=O)(=O)c1c(C)cc(C)cc1C +Cc1ccc(C(=O)Nc2ccc(N)c(C(F)(F)F)c2)cn1 +Cc1nc(-c2ccsc2)sc1C(=O)N(C)CCC(F)(F)F +Cc1nc(C(=O)Nc2ccccc2F)nn1-c1ccccc1 +N#Cc1c(NC(=O)CN2CCc3ccccc3C2)sc2c1CCC2 +Cc1cc(C(=O)N2CC3C4CCC(CC4)C3C2)c2c(C)noc2n1 +CC(=O)N1CCCc2cc(S(N)(=O)=O)ccc21 +Cc1ccc(CNC(=O)c2ccc(O)c(Cl)c2)c(N(C)C)c1 +COCCNS(=O)(=O)c1ccc(-c2c(C)noc2C)cc1 +C=CCn1cc(CNC(C)Cc2cnccn2)c(C)n1 +CN(CC(=O)NC(C)(C)C)C(=O)c1c(F)cccc1Cl +O=C(Cc1ccc(F)cc1)NCc1nc2ccccc2s1 +O=C(NCc1nnc2n1CCCCC2)NC1CCCCC1O +CCCCNC(=O)Cc1noc(C2=Cc3cc(F)ccc3OC2)n1 +CCOc1ccc(CCC(=O)Nc2cccc(S(N)(=O)=O)c2)cc1 +CN(CC(=O)NC1CCCCCC1)C1=NS(=O)(=O)c2ccccc21 +CC(NCC(=O)Nc1ccncc1)c1ccc(F)c(Cl)c1 +Cc1cc(C)c2c(-c3ccccc3)nc(SCC(N)=O)n2n1 +Cc1cc(C)c2ccc(C(=O)N3CCCC(O)(CO)C3)nc2c1O +Cc1cnn(CC2CCCN2c2ncnc3ccccc23)c1 +Nc1nonc1C(=O)Nc1c(F)cc(F)cc1Br +O=S(=O)(NCC1(O)CCc2ccccc21)c1ccc(F)cc1F +CCCNC(=O)c1cccc(C(=O)Nc2nc(CC(N)=O)cs2)c1 +COc1ccc(C(C)=O)cc1S(=O)(=O)NCc1ccco1 +CC1CCC(NC(=O)N(C)CC(=O)N2CCOCC2)CC1 +O=C(c1cccnc1)C1CCCN(Cc2cc(=O)c3ccccc3[nH]2)C1 +Cc1cc2oc(=O)cc(C)c2cc1NC(=O)N1CCCC1CO +Cc1cc(OC(=O)C2COc3ccccc3O2)ccc1Cl +Cc1c(F)cccc1NC(=O)NCc1cc(Cl)ccn1 +O=C(Cn1cnc2ccccc2c1=O)Nc1n[nH]c2ccccc12 +O=C(CCc1nc2ccccc2c(=O)[nH]1)OC1CCCCC1=O +COC(=O)C1(N(C)C(=O)C(C)C2CC2)CCCCC1 +COc1ccc(-c2csc(NC(=O)CCc3ccco3)n2)cc1F +Cc1cc(Cl)ccc1NC(=O)C(C)Oc1cccc(N)c1 +CC(C)CN(Cc1cnn(C(C)(C)C)c1)CC(F)(F)F +Nc1nncc(-c2cccnc2)c1C(=O)N1CCCCCC1 +Cc1nc2oc3c(=O)n(CC(N)=O)cnc3c2c2c1CCCC2 +COCc1nnc(NC(=O)c2cnc(C3CC3)nc2N)s1 +CCCNC(=O)CC1CCN(C(=O)C(C)(C)C)CC1CC +COCCOc1ccc(CNC(=O)N2CCCC(C)CC2)cc1 +N#Cc1ccc(OCCOc2cccc(-n3cnnn3)c2)cc1 +C=CCNc1nnc(SCC(=O)NC(C)C)s1 +CC(C)Oc1cc(C(=O)NCC(C)c2ccc(F)cc2)nn1C +Cc1cc2c(cnc3ncnn32)c(=O)n1NC(=O)C(C)C +O=C(COC(=O)Cc1ccccc1F)Nc1ccccc1 +CC(NC(=O)c1ccc(NC(=O)c2cccnc2)cc1)c1ccccc1 +O=C(CN1CCNc2cc(F)ccc21)OC1CCCC1 +COc1ccsc1C(=O)NCc1ccccc1N1CCOCC1 +Cc1cc(C)nc(-n2nc(C)c(Cc3c[nH]c4ccccc34)c2O)n1 +CCCN(CCC)C(=O)NC(C)c1cccc(S(N)(=O)=O)c1 +COc1ccc2nc(SCC(=O)Nc3c(C)n[nH]c3C)[nH]c2c1 +CC(=O)Nc1cc(NC(=O)NCc2ccc(C)cc2C)ccc1Cl +Cc1nc(CCSc2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cs1 +O=C(NCc1ccccc1N1CCCCC1)N1CCCC1CO +C=CCNc1ccc(C(=O)Nc2ccc(OC)cc2)cc1 +CCC(O)c1nc2ccccc2n1CCOc1ccccc1 +O=C(NCc1ccc(-c2ccccc2)o1)c1cnc2ccccn2c1=O +O=C(Nc1ccc2[nH]ncc2c1)c1csc2ccccc12 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccc3[nH]nnc3c2)cc1 +COc1ccc(C2CC(O)C(O)C2NC(=O)C2CCCC2)cc1 +CC(=O)Nc1ccc(Oc2ncc(Br)cn2)cc1 +CNC(=O)c1cccc(CNC(=O)CCc2nc(C(C)(C)C)no2)c1 +CCS(=O)(=O)N1CCC(n2nc(C3CC3)ccc2=O)CC1 +COc1cc(NC(=O)C(C)NC(C)=O)c(OC)cc1Cl +Cc1nn(CC(=O)NCc2ccc(OC(C)C)cc2)c2ccccc12 +CCc1ccccc1NC(=O)NCc1ncn(C)n1 +COCc1cc(C)nc2sc(C(=O)NC3CCCCC3)c(N)c12 +Cc1ccc(C)c(OCCCCC(=O)N2CCNC(=O)C2)c1 +C=CCOc1cccc(NC(=O)CCc2c(C)nc(C)[nH]c2=O)c1 +Cc1ccc(S(=O)(=O)NC2=NS(=O)(=O)c3ccccc32)cc1 +CCn1cnnc1CNC(=O)c1ccc2c(c1)OCO2 +OCCn1c(CCOc2ccccc2)nc2ccccc21 +CC1CN(C(=O)CC2OC(=O)c3ccccc32)c2ccccc2S1 +NC(=O)Cc1ccc(NS(=O)(=O)c2ccc3c(c2)CCCC3)cc1 +CC1CCCCC1CNC(=O)c1cc(N)ccc1Cl +Cc1cc(OCCN2CCOCC2)nc(C)c1N +COCCOc1ccc(NC(=O)N2CCCC2c2cc(C)no2)cn1 +CCc1nc(CCOc2ccccc2F)sc1CO +CC(C(=O)c1ccc(Cl)cc1Cl)n1ccnc1 +O=C(CCC(=O)Nc1nc(C2CC2)cs1)Nc1nccs1 +CCCCNC(=O)c1n[nH]c2cc(Cl)ccc12 +NC(=O)C1(NC(=O)c2cc(-c3cccc(Cl)c3)on2)CCCCC1 +O=c1ccc(C(F)(F)F)nn1Cc1ccc(-n2ccnc2)nc1 +Cc1noc(C)c1CN1CCOC2CN(C(=O)c3ccccn3)CC21 +CN(C(=O)Cc1cccc2cccnc12)C1(C#N)CCC1 +COC(=O)c1sccc1NC(=O)COc1cccc2cccnc12 +Cc1cc(C)n(-c2ccc(CNC(=O)NC(C)C3CCCO3)cn2)n1 +CC(C)C(Sc1ccccc1)C(=O)N1CCC2(CC1)OCCO2 +Cc1ccc(NC(=O)N(C)CC(=O)NC(C)(C)C)cc1 +CC(C)NC(=O)CN1CCN(C(=O)OC(C)(C)C)CC1 +CCOC(=O)NCCC(=O)Nc1c2c(nn1C)CCC2 +CC(=O)NCC(=O)NCC(C)c1nc(-c2ccccc2)no1 +CSc1c(CC(=O)NCCCO)n(C)c2ccc(C)cc12 +COc1ccc(C)cc1NC(=O)c1ccc2c(c1)OCO2 +Cc1cc(C)n(C(C)C(=O)Nc2sc(C)c(C)c2C(N)=O)n1 +COc1ccc(OCCCc2nc3cc4c(cc3[nH]2)OCCO4)cc1 +CC(Sc1ncccc1N)C(=O)NC(C)(C)C +COc1cc(CNC(=O)c2sc3ncn(C)c(=O)c3c2C)ccn1 +CCn1c(CCNC(=O)c2cccc(N(C)C)c2)nc2cccnc21 +CCCCCNC(=O)Nc1ccc(OC)cc1OC +N#Cc1cnn(C2CCCOc3c(F)cccc32)c1N +CCCC1CN(C(=O)Nc2cnn(Cc3ccccc3)c2)CCO1 +CC(=O)c1ccc(NC(=O)CSc2ccccc2N)cc1 +CCOC(=O)CCNC(=O)NCc1ccccn1 +Cc1cc(CNc2nccc(N3CCC(O)C3)n2)cnc1C +CCc1nnc2sc(Cc3ccc(OC)c(OC)c3)nn12 +COc1cccc(Cc2nnc(-c3ccc4c(c3)OCO4)o2)c1 +O=C(c1cc(Cl)ccn1)N(CCO)C1CCCC1 +COC(=O)c1ccc2oc(-c3cc(N)[nH]n3)nc2c1 +Cc1ccc(NC(=O)COC(=O)c2ccco2)c(C)c1 +Nc1nc2ncc3c(c2c(=O)[nH]1)CC(c1ccccc1)CC3=O +COCCn1c(-c2ccc(C)c(C)c2)ccc(CC#N)c1=O +CCNC(=O)c1ccc(NC(=O)NC(C)c2ccccn2)c(C)c1 +Cc1nc(N)c2c(n1)CN(C(=O)OC(C)(C)C)C2 +O=C1CN(C(=O)c2cc3c(s2)CCC3)CCN1 +COc1ccc2c(c1)N(C(=O)CCSc1ccccn1)CC(C)O2 +CC(O)CC1CCCN1C(=O)NCc1ccnc(OC(C)(C)C)c1 +Cc1cc(C(=O)N(C(C)C)C2CCOCC2)c(C)s1 +NC(=O)c1ccc(NC(=O)Cc2ccc(Cl)cc2Cl)cc1 +O=c1[nH]c(-c2cccnc2)nc2sc3c(c12)CCCC3 +Cc1nc(C)c(C(=O)NCc2cnn(C)c2)s1 +Nc1cnccc1S(=O)(=O)Cc1ccc(Cl)c(Cl)c1 +OC(COc1ccc(-c2ccccc2)cc1)Cn1cncn1 +Cc1cc2nnc(SCCC(=O)c3ccc(F)cc3)n2c(C)n1 +CCCCN(CC(F)(F)F)C(=O)c1ccc(=O)n(C)c1 +CC(C)n1nccc1NC(=O)NCCCSc1ccc(F)cc1 +COCC(O)CN(C)C(=O)c1ccc(F)cc1F +CCOC(=O)C1=C(COC(=O)c2cc(C)no2)NC(=O)NC1C +O=c1[nH]c(=O)n(Cc2ccccc2)c2ncn(Cc3ccco3)c12 +CCc1nnc(CN2CC(C)Oc3ccc(Cl)cc32)o1 +Cc1cc(C(=O)N2CC(C(=O)Nc3ccc(F)cc3F)C2)no1 +Cc1ccc(CCCC(=O)N(C)CCN2CCOCC2)cc1 +CN(CCC#N)C(=O)Cn1c(=O)c2c(ncn2C)n(C)c1=O +COCC(=O)Nc1ccc(Cl)cc1-c1nc2ccccc2[nH]1 +NC(=O)c1ccc(N2CCCC2)c(NC(=O)c2ccc3c(c2)CCC3)c1 +N#CCCN(Cc1c(F)cccc1Cl)C1CC1 +Cc1cc(F)c(F)cc1C(=O)N1CCCCC1C +CSc1nc(C)c(CCC(=O)OC(C)c2ccccn2)c(=O)[nH]1 +O=C(Nc1ccncc1)NC(c1ccccc1)c1ccco1 +Cn1c(N)c(NC(=O)C2COc3ccccc3O2)c(=O)n(C)c1=O +CNC(=O)CNC(=O)c1cnc(-c2ccccc2)nc1 +COc1ccc(CC(=O)Nc2ccccc2F)cc1C +Cc1n[nH]cc1NS(=O)(=O)c1ccc(Br)c(F)c1 +CCOC(=O)N1CCN(c2cccc(OC)c2)CC1 +CCN(CC)C(=O)CC(C#N)c1c(Cl)cccc1Cl +O=C(Nc1c[nH]c(=O)[nH]c1=O)c1ccc(Cl)cc1 +COc1ccccc1CCNC(=O)c1cccc(N)c1 +CCN(CC)C(=O)N1CCOc2ccc(F)cc21 +CCc1nnc2c(NC(=O)COc3ccc(F)cc3)cccn12 +Nc1ncccc1Cn1c(CCO)nc2ccccc21 +Cn1cc(Cl)cc1C(=O)N1CCC(c2nncn2C)CC1 +CCC1CN(C(=O)Cc2ccc(-n3cnnn3)cc2)CCO1 +COc1cc(C#N)ccc1OCC(=O)NCCc1cccs1 +COCCCCSc1nnc(NC(C)=O)s1 +COCC(C)NC(=O)Nc1cccc(NC(=O)c2ccoc2)c1 +COc1ccc(OC)c(CNC(=O)c2ccnc3ncccc23)c1 +O=C1COc2ccc(C(=O)NCC(O)c3ccc(F)cc3)cc2N1 +Cc1sc2ncn(CCC#N)c(=O)c2c1-c1ccc(F)cc1 +COc1cc(NCC2CC(=O)N(C3CC3)C2)nc(N)n1 +CCCn1c(=O)n(C)c(=O)c2c(SCOC)nc(C(C)C)nc21 +COCCN(CCC#N)Cc1coc2ccccc12 +Cc1ccc(F)c(NC(=O)CCc2nc(-c3ccccn3)no2)c1 +CCOc1ccccc1C(=O)Nc1ccc(C(=O)N(C)C)cc1 +O=C1COc2ccc(S(=O)(=O)NCCOc3ccccc3)cc2N1 +CCc1nnc(NCc2cccc(-c3nc[nH]n3)c2)c(C#N)c1CC +CCOC(=O)C1CCCN(S(=O)(=O)c2cnn(CC)c2)C1 +CN(C(=O)CC1Oc2ccccc2NC1=O)c1ccccc1 +COc1cc(CNC(=O)c2cc(C)nn2C)ccc1OCC(N)=O +COC1CCCC1OC(=O)CCc1cc(F)ccc1F +CC(C)C(=O)NC(c1nc(-c2cccnc2)no1)C(C)C +Cc1noc(CN2CCN(C(=O)Cc3c(F)cccc3F)CC2)n1 +Cn1c2ccccc2c2nn(-c3ccccc3)c(=O)cc21 +CCn1ccc(C(=O)Nc2nc3ccc4nc(C)sc4c3s2)n1 +O=C(CCCc1cccs1)N1CCOC(c2ccc(F)cc2)C1 +COc1cc(C)nc(COC(=O)c2cn(C)nc2-c2cccs2)c1 +CCCc1c(C(=O)NC2CCCC2)nnn1-c1ccc(OC)cc1 +Cc1nc(C(C)C)sc1C(=O)Nc1ccc2c(c1)OCO2 +CCCN(CC(=O)Nc1ccccc1OC)C(=O)c1cccs1 +O=c1c(Br)c[nH]c2c(Br)cccc12 +CC(=O)N1CCCn2nc(CNc3ncccc3C(N)=O)cc2C1 +COc1ccc(N)cc1COc1cc(C)ccc1C +Cc1nc2cc(NC(=O)Cc3ccc(F)cc3F)ccc2o1 +Cc1cccc(CC(=O)NCc2cc(=O)n(C)c(=O)n2C)c1 +CC(CCc1ccccc1)NC(=O)c1ccsc1 +COC(=O)Cc1csc(NC(=O)c2cnn(C)c2C)n1 +Cc1cc(N)c2ccnc(C(=O)Nc3ccc4cn[nH]c4c3)c2c1 +COc1ccc(-n2c(C)nc3ccccc3c2=O)cc1 +Cc1ccnc(NC(=O)c2ccc(Cn3cncn3)cc2)c1 +CC(C)(C)OC(=O)NCCCNC(=O)c1c[nH]c2cccc(F)c12 +O=C(C1CCn2c(nc3ccccc32)C1)N1CCC2(CC1)OCCO2 +CC(C)(C)n1cc(NC(=O)c2scnc2C2CC2)cn1 +O=C(CCNC(=O)N1CCC(CO)CC1)NC1CCCC1 +O=C(NCCCc1c[nH]c2ccccc12)NCC1CCOC1 +COc1ccc(C(=O)N2CCN(C(=O)c3ccco3)CC2)cn1 +CC(=O)c1cccc(NS(=O)(=O)c2ccc(F)c(C)c2)c1 +CC(=O)c1c[nH]c(C(=O)N(CCC#N)CCC(F)(F)F)c1 +CC1(C)Oc2ccc(N)cc2N(Cc2ccccc2)C1=O +COc1cccc(C(=O)Nc2ccc3nc(-c4cccnc4)[nH]c3c2)c1 +Cc1ccc(NC(=O)C2CCCN2C(=O)OC(C)(C)C)cc1C +COCCn1nc(C(=O)Nc2cc(F)ccc2OC)ccc1=O +O=C(CCc1ccc(Cl)c(Cl)c1)N1CCN(CCO)CC1 +CCCN(c1ncnc2sc3c(c12)CCNC3)C1CCCCC1O +Cc1noc(NC(=O)c2cc(Br)ccc2F)n1 +CCCOc1c(N)cc(C2OCCCO2)cc1OC +CC(=O)NC1CCCN(CC(=O)NC(C)c2ccc(Cl)cc2)C1 +Cc1cc2nc(C(NC(=O)c3ccnn3C)C(C)C)cc(O)n2n1 +COc1ccnc(NC(=O)c2ccc(Oc3cccnc3)cc2)c1 +COCc1c(Cl)cccc1NC(=O)NC1CCCC2OCCC12 +COc1cccc(CS(=O)(=O)NCc2cn3c(C)cccc3n2)c1 +CC(=O)N1CCN(C(=O)CC2OC(=O)c3ccccc32)CC1 +O=S(=O)(Cc1ccccc1Cl)NCc1ccccc1 +CC1(C)CN(C(=O)c2cc(C3CC3)on2)CCO1 +CNC(=O)NCC(=O)Nc1nnc(C(C)(C)C)s1 +CCC1CCCC(NC(=O)c2cc(C)c(C)c(S(N)(=O)=O)c2)C1 +Cc1cc(-c2nc(Cc3cccc(Cl)c3)nn2CCO)nc(C)n1 +CCC1(CO)CCCN(c2nc(C)c3ccc(OC)cc3n2)C1 +Cc1nc2nccc(-c3ccc(-c4ccccc4)cc3)n2n1 +COCCCNC(=O)c1cn(Cc2ccccc2C)nn1 +CC1CC=C(c2n[nH]cc2CNCCc2ccccc2F)O1 +CC(NC(=O)Nc1ccccc1)C(=O)Nc1ccncc1 +N#Cc1ccccc1NCc1c(F)cc(F)cc1F +Cc1ccc(CN(C)C(=O)NCc2cccnc2-n2cncn2)s1 +Cc1ccc(S(=O)(=O)N2CCCN(C)c3ccc(F)cc32)s1 +CC(C)n1cnnc1CN(C)C(=O)C1Cc2ccccc2O1 +COCCCN(C)C(=O)NC(c1ccccc1)c1ccccn1 +CCc1ncnc2c1CCN(C(=O)C1CCCO1)CC2 +Cc1cc(C(=O)Nc2ccc(Cl)c(N)c2)ccc1F +O=C(c1ccccn1)N1CCC(c2[nH]ncc2-c2ccncc2)CC1 +Cc1cc(C(=O)NCCc2nncn2C(C)C)c2c(C)nn(C)c2n1 +CC1CN(C(=O)N2CCCC2)CC12CCN(c1ccsc1)C2=O +CC1CCN(C(=O)C(C)Sc2nccn2-c2cccc(F)c2)CC1 +COc1cccc(C(=O)NCC(=O)Nc2ccc(C)cc2)c1 +Cc1ccc(CNC(=O)Cn2cnc3sccc3c2=O)cc1 +CCn1cc(C(=O)N2CCN(C(=O)c3cccc(F)c3)CC2)cn1 +CCS(=O)(=O)c1ccc(C(=O)NC2CCCCC2)cc1 +CCC(Cn1nc(-c2cccs2)oc1=O)NC(=O)c1cc(C)no1 +Cc1c(C(C)NC(=O)CCCn2cncn2)oc2ccc(F)cc12 +Cc1cc(C)c2c(c1)CCNC2c1scnc1C +COC(=O)NCC(=O)Nc1ccc(Oc2cccc(C)c2)cc1 +CCSc1cc(C(=O)NC(C)C(=O)NC)ccn1 +CCCS(=O)(=O)N1CCCC(C(=O)OCC)C1 +O=C(NCc1cccc(Cl)c1)c1ccc2c(c1)OCCO2 +O=C(Nc1cccc(-c2cn[nH]c2)c1)c1n[nH]c2c1CCC2 +O=C(C(O)c1ccccc1)N1CCc2ncnc(NCCO)c2CC1 +COc1cc(C(=O)NCCc2cc(C)cc(C)c2)cc(OC)c1OC +O=C(c1ccc(-n2ccnn2)cc1)N(C1CC1)C1CCc2ccccc21 +CC(C)C(C)N(C(=O)NCc1csc(N(C)C)n1)C1CC1 +COCCN1C(=O)CC(C(N)=O)C1c1cnn(C)c1C +Cc1cc2cc(CNCc3ccccc3)c3nnnn3c2cc1C +CC(=O)Nc1ccc(C)c(S(=O)(=O)NCc2cccc(C)n2)c1 +COc1ccc(CNC(=O)Nc2nnc(C3CC3)s2)cc1F +COc1ccccc1NC(=O)c1ccc(OC(C)=O)c(OC)c1 +CCCOc1cc(C)ccc1NCC(=O)N1CC(C)OC(C)C1 +CCN(C)S(=O)(=O)c1csc(C(=O)Nc2ccccc2C)c1 +COc1ccc2nc(C(=O)NCC(C)(C)C)n(C)c2c1 +Cc1noc(C)c1CCC(=O)NCCn1ccc2ccc(Cl)cc21 +COc1cccc(CCC(=O)Nc2n[nH]c(-c3ccco3)n2)c1 +CCNC(=O)CN1CCN(C(=O)c2sccc2Cl)CC1 +O=c1[nH]c2ccc(-c3csc(NC4CC4)n3)cc2o1 +O=C(CCCOc1ccc(F)cc1)N1CCOCC1C1CC1 +CC(C)c1ccc(C2CC(c3cccnc3)=Nc3ncnn32)cc1 +CCCc1nc(NCc2ccco2)c2cnn(C)c2n1 +CS(=O)(=O)N1CCN(c2ccc(-n3cccc3)nn2)CC1 +Cc1nc(C(=O)NC(C)c2nncn2C)nn1-c1ccccc1Cl +CCCNC(=O)Cn1ncc2ccsc2c1=O +Cc1nnc(SC(C(=O)N2CCc3ccccc3C2)C(C)C)s1 +COc1ccc(CN(C(=O)CSc2nc(C)cs2)C2CC2)cc1 +CNC(=O)Cc1noc(Cc2ccccc2C(F)(F)F)n1 +O=C(C#Cc1ccccc1)Nc1ccc(Oc2cccnc2)nc1 +Cc1ccc(-n2ccnc2SCC(=O)NCC(C)C)c(C)c1 +CCCCc1nnc(SCC(=O)Nc2cccc(C)c2C)n1N +O=C(Cc1nc(-c2ccc(O)cc2O)cs1)N1CCOCC1 +COc1ccc(OC)c(S(=O)(=O)N2CCCCC2C(N)=O)c1 +CCc1nnc(NC(=O)CCc2ccc(OC)c(OC)c2)s1 +COc1ccc(C(O)CN2CCN(c3ncccn3)CC2)cc1OC +CN(C)c1cccc(CN(C2CC2)S(=O)(=O)c2cccnc2)c1 +N#Cc1ccccc1NC(=O)N1CCOC12CCCCC2 +Cc1ncc(CNC(=O)Nc2ccc3c(c2)OC(C)(C)O3)s1 +Cc1nc(SCCOc2ccccc2)c(C(N)=O)c(C)c1C +Cc1nccc(N2CCCC2c2ccnc(-c3ccccn3)n2)n1 +COCCN(CC(C)C)C(=O)Cc1ccc(F)cc1 +CCN(CC(=O)NC(C)(C)C)C(=O)CNC(=O)c1ccco1 +c1ccc2c(c1)CCCC2N1CCN(c2nccs2)CC1 +CN(CCNS(C)(=O)=O)S(=O)(=O)c1cccc(Cl)c1F +CNC(=O)c1ccc(NC(=O)c2ccc(NC(C)=O)cc2)cc1Cl +Cc1c(Cl)cccc1-n1nnnc1-c1ccco1 +COc1cc(C(=O)OCC(=O)NCC(=O)N(C)C)cc(Cl)c1O +Cc1occc1-c1nnc(SCc2ccc(-n3cccn3)cc2)o1 +Cc1nc2ncccc2c(=O)n1CCNC(=O)c1ccc2cc[nH]c2c1 +CCOC(=O)c1ccc(CNC(=O)NCC2CC2)cc1 +O=C(CCn1c(=O)oc2ccccc21)N1CCCCCC1 +O=C(NCc1nnc2n1CCC2)Nc1nc2ccccc2s1 +CC(=O)Nc1cccc(C(C)OC(=O)CCc2ccc(F)cc2)c1 +c1ccc(COc2ccc(CN3CCOCC3C3CC3)cc2)nc1 +O=C(CCCn1cccc1)N1CCN(c2ncccn2)CC1 +CN(C(=O)CN1CCOC(Cn2cncn2)C1)C1(C#N)CCCCC1 +COc1cc(NC(=O)N2CC3CCCCC3C2)ncn1 +COc1ccsc1S(=O)(=O)NC1(c2ccccc2)CC1 +O=C(NC1CCCC1)c1ccc(-n2cnc3ccccc32)cc1 +O=C(NCCc1cccs1)c1ccc(N2CCCC2=O)cc1 +Cc1sc(=O)n(CC(=O)NCCC(=O)N2CCCCC2)c1C +Cc1ccc(Cl)c(NC(=O)c2cn3c(n2)CCCC3)c1 +O=C(CSc1n[nH]c(=O)n1C1CC1)NCCc1cccs1 +CNC(=O)N1CCC(c2nc3cc(Cl)ccc3o2)CC1 +CC(NC(=O)Cn1nnc(-c2ccccc2)n1)c1ccccn1 +O=C(OCc1nnnn1C1CC1)c1cc(=O)[nH]c2ccccc12 +COc1ccc(Br)cc1NCc1cc(C)on1 +CCOc1ccccc1NC(=O)N1CCCC(CO)C1 +Cc1ccccc1N1CC(C(=O)N2CCN(C)CC2)CC1=O +N#Cc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1Cl +CCn1c(SCC(N)=O)nc2cc(S(N)(=O)=O)ccc21 +CC(C)Cc1ccc(C(C)C(=O)N2CCN(CCC#N)CC2)cc1 +CN(CC(=O)NC(C)(C)C)C(=O)CCNC(=O)c1ccsc1 +CNC(=O)c1cccc(NCC(=O)NC2CC2)c1C +N#Cc1cccn(Cc2ccc3c(c2)OCO3)c1=O +OCC1OC(n2cnc3c(NC4CCCCC4)ncnc32)C(O)C1O +CCC(C)C(=O)NCC(=O)Nc1c2c(nn1C)CCC2 +O=C(CNC(=O)C1COCCO1)NCc1ccccc1 +N#Cc1cccc2nc(-c3c(F)cccc3Cl)nn12 +Cn1ncc2c(Nc3ccc(Br)cc3F)ncnc21 +CCc1nc2nnc3c(=O)n(Cc4ccccc4)ccc3n2n1 +Cc1cc(C)nc(SCC(=O)NCCN2CCOCC2)n1 +Cc1occc1C(=O)Nc1ccnc2ccc(F)cc12 +O=C(COc1cccc(F)c1)Nc1cccc2cnccc12 +CS(=O)(=O)Nc1ccccc1C(=O)N1CCCCC1 +CC(C)C1CN(C(=O)C(C)n2ccnc2)c2ccccc2N1 +CC(C)C(C)NC(=O)c1csc2c1CCCC2 +Cc1ccc(NCC(=O)N(C)Cc2ccccc2)cc1 +O=c1[nH]cnc2oc(-c3sc4ccccc4c3Cl)nc12 +CCOC(=O)c1[nH]c(C)c(C(=O)N2CCCC(C)C2)c1C +COc1ccccc1C(C)(C)CNC(=O)c1ccc(=O)n(C)n1 +O=C(CCO)N1CCCC(N2CCN(c3ccccc3F)CC2)C1 +O=C(COC(=O)c1ccccc1F)NCc1cccc(Cl)c1 +C=CCn1c(SCC(=O)c2ccc(F)cc2F)nnc1C1CC1 +O=C(NC1CCN(c2ccc(F)cc2F)C1)c1cccnc1 +O=C(COC(=O)C1COc2ccc(Cl)cc2C1)C1=NC=CC1 +CC(=O)NC1C(OC2CCCCC2)OC(CO)C(O)C1O +CCN(CCO)C(=O)c1cc2cc(Cl)ccc2o1 +CN(C)C(=O)CNC(=O)NCC(=O)N1CCCc2ccccc21 +O=C(CCc1ccc2[nH]ccc2c1)NCc1ccccc1 +COCCCN1CC2(CCCN(c3cccc(C#N)n3)C2)CCC1=O +FC(F)(F)CNCc1nnc(-c2ccccc2)o1 +O=C(NC1CCCC1)c1ccccc1C(=O)NC1CCCC1 +Cc1ccccc1C(=O)NCC1Cc2ccccc2O1 +Cc1[nH]ncc1S(=O)(=O)NC(C)C1CCCO1 +COCCN(CCOC)C(=O)Nc1cccc2c3c(oc12)CCCC3 +CN(CCc1noc(C2CC2)n1)C(=O)C1Cc2ccccc2CN1C +CCN(CCO)C(=O)CCc1ncc(-c2ccccc2Cl)o1 +CS(=O)(=O)c1ccccc1C(=O)Nc1ccc2c(c1)CCC(=O)N2 +Cc1ccc(C(C)NC(=O)N(C)Cc2nccn2C(F)F)o1 +Cc1cccnc1CNC(=O)NCc1cn(-c2ccccc2)nn1 +COc1cc(C)c(C)cc1S(=O)(=O)CC(C)C#N +Cc1ccc(C(=O)N(C)C)cc1NCc1ccc(F)cc1F +CNC(=O)c1cccc(NC(=O)CN2c3ccccc3CC2C)c1 +Cc1nc(CCNc2nc3ccccc3c(=O)[nH]2)cs1 +CC(=O)c1ccc(CNC(=O)c2cc[nH]n2)nc1C +O=C(Nc1cccc(-c2ccn[nH]2)c1)c1cc2ccccc2o1 +COc1cccc(NC(=O)Nc2ccc(F)c(NC(C)=O)c2)c1 +C=CCN(CCc1ccccc1)C(=O)Nc1cccnc1 +CCCN(CC(=O)NC)C(=O)C1(c2ccc(F)cc2)CC1 +COc1c(F)cc(NC(=O)CN(C)C(C)=O)cc1F +O=C(NCc1ccc2c(c1)OCO2)c1cccnc1Oc1ccccc1 +Cn1nnc2c(N3CCN(C(=O)C(C)(C)C)CC3)ncnc21 +Cc1cc(C)cc(N2CC(C(=O)N(C)C(C)C)CC2=O)c1 +Nc1ccc2c(c1)N=C(Nc1ccc(Cl)cc1)CO2 +COCC(C)(O)CNC(=O)COc1ccccc1F +Cc1cc(C(=O)NC(C)C)ccc1NC(=O)c1ccco1 +CCCc1nc(C(N)=O)c2[nH]c(=O)n(-c3cccc(OC)c3)c2n1 +NC(=O)c1cc(N2CCCC(C(=O)N3CCOCC3)C2)ccn1 +CCc1ccccc1NC(=O)CSc1nc(C)cc(=O)[nH]1 +Cc1ccc(CN2CCC3OC(C(=O)N(C)C)CC32)s1 +COc1ccc(CNC(=O)Nc2ccc(OC)c(F)c2)cc1O +C=CCNc1nc(Nc2ccccc2)c2cnn(C)c2n1 +CCOC(=O)C(C)Oc1ccc(S(C)(=O)=O)cc1 +Cc1cc(NC(=O)C(C)Sc2ccccn2)c2ncccc2c1 +O=C(NCCOc1ccccc1)c1cnn(-c2ccc(F)cc2)n1 +Cc1cc(C)c2nc3c(cc2c1)CN(Cc1ccc(C)o1)C(=O)O3 +CNS(=O)(=O)CC(=O)N(Cc1ccsc1)c1ccccc1 +O=C(Cn1c(-c2ccccc2)noc1=O)NC1CCCCC1 +CC(NC(=O)C1CCC(=O)N1Cc1ccccc1)c1ccccc1 +CCOC1CCN(C(=O)c2ccc(Br)cc2O)CC1 +Cc1noc(NC(=O)Cc2ccc3ccccc3c2)n1 +Cc1cnn(CCNCc2cnc(N3CCOCC3)nc2)c1 +Cc1cc(S(=O)(=O)NCC(O)(c2ccccc2)C2CC2)ccc1F +COCn1c(-c2ccccc2)nc2c(N)cccc21 +Cc1sc2ncnc(NCCCc3n[nH]c(=O)[nH]3)c2c1C +CC(=O)Nc1ccc(F)c(C(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +CCCC(C)(C)NC(=O)c1cnn(-c2ccncc2)c1C +CCc1onc(C)c1NC(=O)N1CCN(Cc2cccs2)CC1 +Cc1noc(-c2ccc(C(=O)NCCCO)cc2)n1 +CN(Cc1cccc(C(N)=O)c1)C(=O)CC(F)(F)F +COc1ccccc1OCc1cccc(CCC#N)c1 +COc1cc(NC(=O)Cc2c[nH]c3ncccc23)cc(OC)c1 +CCc1nnc2n1CCN(C(=O)c1ccc(Cn3ccnc3)cc1)C2 +CS(=O)c1nncn1-c1ccc2nnc(-c3ccccc3)n2n1 +Cc1ccccc1CNC(C)C(=O)NCc1ccco1 +Cc1cc(CN(C)C(=O)Cc2c(Cl)cccc2Cl)no1 +COc1nonc1NC(=O)CSc1nc2ccccc2[nH]1 +COCCOc1ccc(NS(=O)(=O)c2cc(C)ccc2C)cc1 +O=C(CCCc1nc(C2CC2)no1)N1CCCCC1c1nccs1 +CC(=O)c1ccc2c(c1)c(=O)oc(=O)n2Cc1ccccc1 +Cc1cccnc1NC(=O)CCc1c(C)nc2nc(N)nn2c1C +COCCN1CCN(C(=O)C2(O)Cc3ccccc3C2)CC1=O +CCc1nc(C)cn1S(=O)(=O)c1ccc(OC)cc1 +COc1cccc(-c2cc(C(=O)N3CCCC(C)C3)n[nH]2)c1 +Cc1nc(C)c(CC(=O)Nc2cccc(Cl)c2)s1 +CCc1cc2c(CC(O)COC)ncnc2s1 +O=C(NCCCO)c1nnc2ccc(Cl)cc2n1 +COc1cc(C(=O)N(C)C)ccc1OCc1csc(C)n1 +COc1nc(C(C)C)nc(NCc2ccccc2F)c1N +Cn1c(=O)oc2ccc(C(=O)N3CCN(c4ncccn4)CC3)cc21 +COC(=O)Cn1c(=NC(=O)c2nn(C)cc2C)sc2ccccc21 +COC(=O)c1ccc(N2CCC(Nc3ccccc3)C2)nn1 +CNS(=O)(=O)CCN(Cc1cccnc1)C(C)=O +Cc1cc(C)c2nc3c(cc2c1)CN(Cc1ccco1)C(=O)CO3 +CN(C)c1nc2sc(C(=O)Nc3cnn(C)c3)cc2s1 +CCC(C)NC(=O)C(C)NC(=O)COC1CCCCC1 +CC(C)N(CC(N)=O)C(=O)CCNC(=O)c1ccc(F)cc1F +COCCCN(C)C(=O)c1ccc(CNC(N)=O)cc1 +CC(=O)NC(CC(=O)OCC1CCC(=O)N1)c1ccccc1 +O=C(NCc1ccccc1F)c1ccc(-c2ccsc2)nc1 +COCC(C)NC(=O)COc1cc(C)ccc1C(C)C +COC(=O)N(C)c1ccc(NC(=O)NCCc2ccccn2)cc1 +Cc1nn(C)c2[nH]nc(NC(=O)C3CC3c3cccc(F)c3)c12 +Cc1cc(C)cc(NC(=O)c2snc(C#N)c2N)c1 +COC(=O)c1cccc(NCc2ccncn2)c1C +Cc1cc2n(n1)C(c1coc3ccccc3c1=O)Nc1ccccc1-2 +COc1ccc(F)cc1NC(=O)NCCNC(C)=O +CCCS(=O)(=O)c1ccc(-c2cc(C(=O)OC(C)C)[nH]n2)cc1 +Cc1ccn(-c2ccc(NC(=O)c3sccc3C)cc2)n1 +C#CCN1CCC(C(=O)NCC(=O)NC(C)(C)C)CC1 +O=C(NCC1(c2ccc(F)cc2)CC1)c1ccco1 +COc1cccc2c1OC(c1ccc(F)cc1F)NC2=O +Cc1ccc(NC(=O)c2cc(-c3ccccc3)[nH]n2)nc1 +CS(=O)(=O)Nc1ccccc1NC(=O)c1cc2c(F)cccc2[nH]1 +C=C(C)CN(CC)C(=O)Cc1c[nH]c2ccc(OC)cc12 +COC(=O)C(NC(=O)Cc1cccc(C)c1)C(C)C +Cc1nonc1C(=O)N1CCC2(CCCN(CC3CCC3)C2=O)C1 +CN(C)c1ccc(-c2c(C#N)c(N)c(C#N)c3c2CCC3)cc1 +CCOC(=O)c1cccc(NC(=O)c2cccn2-c2cccnc2C)c1 +CN(CCOc1ccccc1F)C(=O)c1c[nH]c2cccc(F)c12 +C=CCOC(C)C(=O)Nc1cc2c(cc1Br)OCCO2 +COc1ccc(C)cc1NCC(O)c1ccccn1 +COc1ccc(OC2CCN(C(=O)c3ccoc3)CC2)cc1 +COc1cccc(OCC(=O)N(C)c2ccc(F)c(F)c2)c1 +O=C(NCc1cccc(OCC(F)F)c1)c1ccncc1F +COc1cccc(C(=O)Nc2c3c(nn2-c2ccccc2)CCC3)c1 +CCCn1ncc(-c2ccc3c(c2)OCO3)c(CO)c1=O +COC(=O)c1cccc(CCNC(=O)N2CCOC(C)(C)C2)c1 +COc1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +CCn1nc(C)cc1C(=O)NCC(=O)Nc1cccc(C)c1 +CC(=O)Nc1ccc(NCCCN2CCOCC2)cc1 +CCn1nnnc1SC(C)C(=O)c1[nH]c(C)c(C(C)=O)c1C +COc1cc(N)c(NC(=O)c2cccnc2)cc1OC +CC(C)c1nc(CSc2nc3ncccn3n2)cs1 +Cc1ccc(-n2nnc(C(=O)NCCS(N)(=O)=O)c2C2CC2)cc1 +CCN(CC1CC1)C(=O)Nc1cccc(NC(=O)C(C)C)c1 +Cc1ccc(C(=O)OCC(=O)NCc2ccccc2)cc1C +Cn1ncc2c(N3CCCC(NC(=O)OC(C)(C)C)C3)ncnc21 +OCc1c(Br)cnn1-c1ccccc1 +COc1ccc(C2CCCN2C(=O)Cn2cccnc2=O)cc1 +Cc1nn(-c2ccccc2)c2sc(C(=O)NCCCC(N)=O)cc12 +CCC(C)NS(=O)(=O)c1ccc(NC(=O)CC(C)(C)C)cc1 +CC(C)C(=O)Nc1ccc(C(=O)Nc2ccccn2)cc1 +O=C1CCC(NC(=O)C2CC2c2ccc(Cl)cc2)CN1 +Cc1csc(N2CCN(C(=O)c3n[nH]c4ccccc34)CC2)n1 +NC(=O)COc1ccc(NC(=O)c2csc(-c3ccco3)n2)cc1 +Cn1nnnc1-c1cccc(NCc2ccc(F)cc2)c1 +CC(C)NS(=O)(=O)c1ccc(Cl)c(C(=O)NC(C)(C)C#N)c1 +CCC1CCc2c(sc(=O)n2CC(=O)N(C)CCC#N)C1 +CCNC(=O)NC1CC(C)(C)Cc2nc(C(C)(C)C)ncc21 +CC1C(c2cc(F)cc(F)c2)CCc2nc(N)nn21 +CCN(CC(F)(F)F)c1nc2ccccn2c1CO +O=C1c2ccccc2NC(c2cc3ccccc3o2)N1C1CC1 +COc1ccc(O)c(C(=O)c2cnn(C(=O)CC(C)C)c2)c1 +COc1c(Cl)cccc1NC(=O)Cc1cccc(OCC#N)c1 +CSc1ccccc1NC(=O)CN(C)C(=O)Cc1cccc(F)c1 +Cc1cccc(NC(=O)c2ccc(C)c(NC(=O)c3ccco3)c2)n1 +COc1ccc(CCNc2cc(C)nc3c(C)c(C)nn23)cc1O +CC(Cn1nc(-c2cccs2)oc1=O)NC(=O)c1ccco1 +CC(=O)Nc1ccc2nc3c(Cl)cccc3nc2c1 +CC(=O)Nc1cccc(C(=O)OCC(=O)NCc2ccc(C)cc2)c1 +CN(CC1CCCCO1)C(=O)C(C)(C)c1ccccc1 +Cc1cc(NC(=O)NCC2CCC(C)(C)CC2)ccc1C(N)=O +Cc1cc2c(=O)n(CC(=O)c3ccc4c(c3)OCCO4)cnc2s1 +COc1ccc(F)cc1C(C#N)CC(=O)NC(C)C +CC(C)C(NC(N)=O)C(=O)NCCc1ccc2c(c1)OCCO2 +Cc1cc(NC(=O)N2CCN(c3ccccc3O)CC2)sn1 +CCn1cnnc1CNC(=O)c1cc(C(C)C)nn1CC +O=C(NCc1ccccn1)Nc1cccc(-c2nnco2)c1 +CCCCN(C)C(=O)Nc1ccc2oc(C3CC3)nc2c1 +Cc1cc2c(cc1C(=O)NC1CCCC1)OCCCO2 +COc1cc2c(c(OC)c1)C(c1nccs1)NCC2 +O=C(NCc1nc(-c2ccncc2)n[nH]1)C1COc2ccccc2C1 +CC(C)(C)NC(=O)COc1cc(Cl)ccc1C(N)=O +O=C(NCCNC(=O)c1ccsc1)c1ccoc1 +CC(Oc1cccc(C#N)c1)C(=O)NCC1CCCO1 +O=C(c1cnc2cc3c(cc2c1)OCCO3)c1cc(F)ccc1O +Cc1nnc(SCC(=O)Oc2ccccc2)n1Cc1ccccc1 +O=C(CCNC(=O)c1cccc2nscc12)NCc1ccccc1 +Cc1cc(C)n(-c2cccc(-c3ccc(S(N)(=O)=O)s3)c2)n1 +COC(=O)C(C)NC(=O)c1cccc(OC2CCCCC2)c1 +Cc1ccsc1C(=O)NCC(=O)NCC1CCCC1 +COC(=O)C1(NC(=O)c2cc(C)c(C)s2)CCCC1 +Cc1ccccc1C(C#N)N(C)S(=O)(=O)c1ccccc1 +COc1c(NC(=O)CN(CCc2ccccc2)C(C)=O)c(C)nn1C +Cc1nn2cc(C(=O)NC3CCCCC3)nc2s1 +CCCN(C)C(=O)c1cccc(S(=O)(=O)NCC)c1 +CCN1C(=O)CCc2cc(NC(=O)c3ccc(Cl)cc3)ccc21 +Cc1cccc(Nc2nccnc2C2CCCN2C(=O)CC(C)C)n1 +Cc1cc(C)n(-c2cc(NCCNC(=O)c3ccco3)ncn2)n1 +Cc1ccc(C(=O)Cc2ccc(Cl)cc2Cl)cn1 +Cc1cc(C)n2nc(CC(=O)N(C)c3cccc4ncccc34)nc2n1 +O=C(Oc1ccc(NC(=O)C2CC2)cc1)c1ccc(NC2CC2)nc1 +COc1ccc(CNC(=O)Nc2ccccc2N(C)C)c(OC)c1 +Cc1cc(-c2c(-c3ccccc3)ncn2C(CO)c2ccccc2)[nH]n1 +COCCCSc1nnc(N2CCCC2)n1C1CC1 +Clc1ccc(CNCCc2cccnc2)c2ncccc12 +CCc1nc(CC(=O)NCc2cccc(C)c2)cs1 +CCN(Cc1cc(Cl)ccc1OC)c1nc(C)nc2oc(C)nc12 +Cc1cc2oc(=O)cc(CN3C(C)COCC3C)c2cc1C +NS(=O)(=O)c1cccc(NC(=O)Cc2cccc3cccnc23)c1 +Cc1noc(C)c1CN1CCOc2ccc(F)cc21 +Cn1ncnc1NC(=O)NC1(Cc2ccccc2)CCCC1 +CN(C)c1cccc(C(=O)Nc2ncn(Cc3ccc(F)cc3)n2)c1 +COCCOc1ccc(NC(=O)NCC(C)C)c(C)c1 +COc1cccc(N2CC(C(=O)N3CC(C)CC(C)C3)CC2=O)c1 +CNC(=O)c1ccc(COc2nnc(-c3ccccc3)o2)cc1 +Cc1ccc(S(N)(=O)=O)cc1C(=O)OCC(=O)c1ccccc1 +C=CCN(C(=O)c1ccc2c(c1)OCCN2C)C(C)C +Cc1cc(C)cc(CCNC(=O)Nc2ccncc2)c1 +C=C(c1ccccc1)C1NCCc2ccc(N)cc21 +CCC(=O)NCC(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 +COc1cc(C)ccc1OCCC(=O)NCC(F)(F)F +Cc1nn(Cc2csc(-c3ccccc3)n2)c(=O)c(C#N)c1C +OC(CNc1cccc(F)n1)c1ccc(Cl)cc1 +NS(=O)(=O)c1ccc(NC(=O)c2ccc3ccccc3n2)c(F)c1 +CC(C)CC(CO)NC(=O)Nc1ccccc1SC(F)F +C=CCOc1ccccc1OCCN1CCOCC1 +Cc1ccc(Cn2nnc(C(=O)Nc3cccc(Cl)c3)c2N)cc1 +COc1ccc(C(=O)N(CCC(N)=O)c2ccc(F)cc2)cc1 +CCCCS(=O)(=O)N1CCN(C(=O)Cc2ccc(C)cc2)CC1 +O=C(Oc1cccc(N2CCCC2=O)c1)c1ccc(-n2ccnn2)cc1 +Cc1cc(C)c(NC(=O)CN(C)C(=O)CNC(=O)C(C)(C)C)c(C)c1 +CC(NC(=O)CSc1nncn1-c1ccccc1)c1cccs1 +Cc1cc(NC(=O)c2ccc(N3CCCC3)nn2)n(C(C)(C)C)n1 +CC(NC(=O)C1CCOC1)c1ccc(F)c(Cl)c1 +O=C(c1c[nH]c(=O)[nH]1)N(CC#Cc1ccccc1)C1CCCC1 +COc1ccc(C(=O)Nc2cc(C)cc(C)c2)cc1N +COCC(O)CN(C)C(=O)NCc1ccc2c(c1)OCO2 +COC(=O)c1nn(-c2ccc(OC)cc2)c(=O)cc1Cl +Cc1ccc(-n2nnc(C(=O)N3CCCC(CC(N)=O)C3)c2C)cc1 +COc1cc2nc(N)c(C(F)(F)F)nc2cc1OC +CC1CCC(NC(=O)Nc2ccc3c(c2)OCC(=O)N3)CC1 +CCNC(=O)c1ccc(-c2cc(C)cc(C)c2OC)nc1N +CNC(=O)c1cccc(NCC(=O)NCCc2ccccc2C)c1C +CC(=O)c1ccc(NC(=O)CSc2nnc(C)n2N)cc1 +CCN1CCOC(CCNC(=O)CC2=CCCCC2)C1 +O=C(CCN1CCOCC1)N1CCc2sccc2C1 +CCC(=O)NCCn1ncc2c(N3CCCCC3)nc(SC)nc21 +CCOC(=O)c1ccc(Cl)c(NC(=O)COC)c1 +O=C(Nc1nc2c(s1)COCC2)c1ccc(F)cc1F +COC(=O)C1CC2CCCCC2N1Cc1nnnn1-c1ccccc1 +COC(=O)CCCNC(=O)c1cc(F)ccc1Br +Cc1cnn(C2CN(Cc3csc(-c4cccs4)n3)C2)c1 +CCCS(=O)(=O)NCC(O)(c1ccccc1)C1CC1 +Cc1ccccc1CCNC(=O)CN1CCn2c(nn(C)c2=O)C1 +Cc1ccccc1C(=O)NC(C(=O)Nc1nccs1)C(C)C +CC(C)C(NC(=O)c1ccccc1)C(=O)C(C#N)c1ccccn1 +O=C(Cc1csc(N2CCCC2=O)n1)N1CCCCC1 +COc1ccc(NC(=O)Cn2cc(Br)cn2)cc1Cl +Cc1c(CNC(=O)Nc2ccc(OC3CCCC3)c(F)c2)cnn1C +Cc1nnc(CNC(=O)CCn2ccc3cc(Cl)ccc32)s1 +CCn1c(SC(C(=O)N(C)C)c2ccccc2)nnc1C1CC1 +COC(=O)C(NC(=O)OCc1ccccc1)=C1CCOCC1 +CCOC(=O)N1CCCC(C(=O)Nc2c(F)cccc2F)C1 +Cc1cc2nccc(C3CCN(C(=O)c4ccccc4F)CC3)n2n1 +N#Cc1nc(COc2ccc(F)cc2)oc1NCc1ccco1 +CC1(O)N(CC(=O)c2cccs2)C(=O)OC12CCCCC2 +Cc1cc(CNC(=O)N(C)C(C)c2sc(C)nc2C)on1 +CC1(NC(=O)NCc2cscn2)Cc2ccccc2C1 +Cc1cc(C#N)nn1-c1ccccc1Br +COC(=O)N1CCCN(C(=O)Nc2ccc(Cl)cc2C)CC1 +Cc1cc(C(=O)OC(C)C(=O)Nc2ccnn2C(C)C)c(C)o1 +Cc1cccnc1NC(=O)C1CCN(C(=O)C(C)C)CC1 +O=C(CN1CCOCC1)N1CCN(Cc2ccccc2F)CC1 +CN(C(=O)CCNS(=O)(=O)c1ccc(F)cc1)C1(C#N)CCC1 +Cc1cccc(CS(=O)(=O)NCC(O)c2ccc(C)o2)c1 +CCOC(=O)c1cnn2ccn(Cc3ccccc3F)c12 +CC(=O)c1cc(-c2cc(C)n(C3CC3)c2C)[nH]c1C +O=C(NCc1ccoc1)Nc1cccc(OC(F)F)c1 +Cc1ccc(C(=O)NCCNc2nnnn2-c2ccccc2)c(=O)[nH]1 +CC1CN(CCc2ccccc2)c2cc(N)ccc2O1 +COCCNC(=O)NCCN1CCCc2ccccc21 +Cc1cc(CN(C)C(=O)c2cc3cnn(C(C)C)c3nc2C)no1 +CC(C)C(=O)Nc1ccc(Oc2ccccc2)cc1N +CN(CC(=O)Nc1cc(F)cc(F)c1)Cc1cc(=O)n2nccc2[nH]1 +O=S(=O)(Nc1nc2ccccc2nc1NC1CC1)c1ccccc1 +Cc1ccc2oc(-c3nccn3CCN(C)S(C)(=O)=O)c(C)c2c1 +O=C(c1ccsc1)N1CCCC1c1ccc2c(c1)OCCCO2 +COc1ccccc1OCCCN1CCC2(CCCO2)CCC1=O +COc1cccc(CN2CCOC(C)C2C)c1OC +COc1ccc(NC(=O)c2ccc(N3CCOCC3)nc2)cc1 +N#Cc1ccc(OCn2nnc3ccccc3c2=O)c(Cl)c1 +O=C(CC1CCCCC1)N1CCN(Cc2cnc3ccccn23)CC1 +CCc1nc(CCNC(=O)NC2CCCC2)cs1 +O=C(c1ccncc1)N1CCN(C(=O)N2CCCC2)CC1 +CCOc1ccc2nc(NC(=O)CCn3nc(C)cc3C)sc2c1 +O=C(NC1CCOc2ccccc21)c1ccc(N2CCNC2=O)cc1 +CC1Oc2ccccc2N(CCC(=O)N2CCCn3ncnc32)C1=O +COC(=O)C(CC(C)C)NC(=O)c1ccc(S(C)(=O)=O)cc1 +CN(Cc1ccc(F)cc1)C(=O)C1CC(=O)N(Cc2ccco2)C1 +CC(NC(=O)c1ccccc1)C(=O)NCC(C)(C)c1ccncc1 +Cn1c(C(F)(F)F)nn(CC(=O)NCc2ccco2)c1=O +O=C(C1CCC1)N(C1CC1)C1CCCc2ccccc21 +CN1C(=O)CC(NC(=O)C(C2CC2)C2CC2)C1c1ccc(Cl)cc1 +COC(=O)c1cc(F)c(C)c(NC(=O)c2scnc2C2CC2)c1 +CCN(CC)C(=O)COc1cc(C(=O)NC2CC2)ccc1N +Cc1cnc(CNc2nc(-c3cccnc3)nc3c2cnn3C)cn1 +CC(C)n1nccc1NC(=O)NCc1ccccc1Cn1cccn1 +Cc1nn(CCC(=O)Nc2cc(-c3ccncc3)n[nH]2)c2ccccc12 +O=C1CCOCCN1Cc1ccccc1C(F)(F)F +COc1cc2c(cc1OC)C(c1ccccc1OC)CC(=O)N2 +CCCCNC(=O)c1ccc(NC(=O)C(C)(C)C)cc1 +O=C(CCn1c(=O)oc2cc(Cl)ccc21)NC1CCC(O)CC1 +CCc1cc(N)cc2c(CC(=O)NC3CCCC3)noc12 +CC(C)OC(=O)CC(O)(c1ccccc1)C(F)(F)C(F)F +O=C(Cc1c(F)cccc1Cl)Nc1ccc(N2CCCC2)nc1 +CCOC(=O)c1c(N(C)S(=O)(=O)c2ccc(C)cc2)n[nH]c1N +CCC(NC(=O)c1ccc(F)c(F)c1F)c1ccc(OC)cc1 +Cc1cc(NC(=O)C2(c3ccc(F)cc3)CC2)n(C)n1 +CCOC(=O)C1CC(=O)N(CCCN2CCOCC2)C1 +Cc1nc(NCCO)c2c(-c3ccc(Cl)cc3)csc2n1 +O=C(NCc1ccc(OCC2CC2)nc1)Nc1c(F)cccc1F +Cc1cc2[nH]ncc2cc1C(=O)c1cccc(N)c1 +Cn1c(=O)c2c(ncn2CC(=O)NCc2ccco2)n(C)c1=O +Cc1cc(C(=O)NC2CCCc3c2cnn3C(C)(C)C)n[nH]1 +CCc1nc(SCC(=O)Nc2c(C)cc(C)cc2C)[nH]c(=O)c1C +CCc1cc(=O)[nH]c(SCC(=O)N(C)c2ccccc2)n1 +COc1ccccc1NC(=O)NCc1nnnn1-c1cccc(F)c1 +C#Cc1cccc(NC(=O)c2nccc3ccccc23)c1 +Cc1ccc(Oc2cccc(C(=O)NCCN3CCOCC3)c2)nn1 +Cc1[nH]c(SC2CCOC2=O)nc1Cc1ccccc1 +CC(C)N(C)C(=O)Cn1cc(Br)ccc1=O +CC(C)CC1COCCN1C(=O)c1cccc(OC(F)F)c1 +Cc1ccc2sc(NC(=O)c3c(C)cnn3C)nc2c1C +CCN(CCCOc1cccc(N)c1)c1ccccc1 +CCC(NC(=O)N1CCC(CC(=O)N(C)C)CC1)c1ccncc1 +O=C1Nc2ccc(F)cc2C12CC(O)=Nc1[nH]ncc12 +Cc1cc(C(=O)NC(C)Cc2ccccc2F)c(C)s1 +COC(=O)C(OC(=O)c1ccc2ccccc2n1)c1ccccc1 +CCN(CC)C(=O)CCNc1ccc(Cl)cn1 +COc1ccc2cc(NC(=O)Nc3ccccc3)cnc2c1 +CN(C)S(=O)(=O)N(C)Cc1csc(C#CCCO)c1 +CCC1CCCN(C(=O)CCCCNC(N)=O)C1 +Cc1cc(C)n(-c2ccc(NC(=O)N(C)CC(C)(CO)CO)cn2)n1 +CN(CC1CCCCO1)C(=O)c1cc(COc2cccc(F)c2)[nH]n1 +OC(CN1CCN(c2ccccc2F)CC1)c1ccc2c(c1)CCO2 +CCC(=O)NC1CCCN(C(=O)CCc2ccc(C(=O)OC)cc2)C1 +COCCNC(=O)C1CCc2sc(C(=O)N3CCCC3)cc2C1 +Cc1c(C)n2c3c(=O)[nH]c(=O)n(C)c3nc2n1CC1CCCO1 +Cc1cccc(COc2ncnc3sccc23)c1 +COc1ccc(NC(=O)NCC(C)N(C)c2ccccc2)cn1 +Cc1ccc(C(=O)N2CCCC2c2cccc3ccccc23)c(=O)[nH]1 +O=C(c1cnc[nH]1)N1CCc2cc(Cl)cc(Cl)c2C1 +CCOc1cc(CO)c(Cl)cc1OCC(N)=O +NC(=O)c1ccc(NC(=O)CCNC(=O)c2ccccc2)cc1 +Cc1ccc(C)c(OCC(O)CN2CCN(c3ncccn3)CC2)c1 +COc1ccc(CNC(=O)CCCc2ccccc2)cc1O +Cc1ncc(C2NCCC2NC(=O)OC(C)(C)C)s1 +CCC1CN(c2cc(C#N)ccn2)CCC(=O)N1Cc1ccccc1 +CC(C)(C)S(=O)(=O)c1ccc(NCc2ccccc2)nn1 +COCCCNC(=O)Cc1coc2cc(C)c(Cl)c(C)c12 +Cc1ccc(OCCCCSc2n[nH]c(N)n2)cc1 +Cc1cc(C(=O)Nc2sc(C)c(C)c2C#N)n(C(C)C)n1 +C=CCN(CC=C)C(=O)Nc1ccc2nc(C)c(C)nc2c1 +COc1ccc(Cc2nnc(N3CCCC3)s2)cc1N +Cn1cnc(CNC(=O)c2cc(Br)cn2C)n1 +CNC(=O)c1cnc(C=Cc2cnc3cc(C)ccn23)s1 +CN(Cc1ccncc1)C(=O)Nc1cccc(F)c1 +Cc1ccc(-c2nnc(-c3ccc(C(=O)Nc4cn[nH]c4)cc3)o2)cc1 +CCOC(=O)C(C#N)(c1ccccc1)N1CCOCC1 +CN(C)S(=O)(=O)NCCCOc1ccc(Cl)cc1Cl +Cc1ccc(CNC(=O)C2c3ccccc3CC(=O)N2C)cc1 +Cc1cccc(-c2nc(Cc3noc(-c4ccncc4)n3)c(C)o2)c1 +O=C1C(N2CCCC3(C2)OCCO3)CCN1c1c(F)cccc1F +COCCN1CCCC2(CCN(c3nccc(OC)n3)C2)C1=O +COc1ccnc(NC(=O)COc2cc(C)ccc2C)c1 +Cc1cc(C)cc(N2CC(C(=O)N3CCC(C)CC3)CC2=O)c1 +COC(=O)c1cc2n(n1)CCCN(C(=O)CCn1cnnn1)C2 +CCc1onc(C)c1NC(=O)CNC(=O)c1cc2ccccc2[nH]1 +CC(C(=O)NCC1CCCO1)N1CCn2c(nnc2C2CC2)C1 +Cn1c(=O)n(CC(=O)Nc2ccc(CCO)cc2)c2ccccc21 +CC1CCCN(C(=O)CNC(=O)c2ccc(F)cc2F)C1 +O=C1CC(C(=O)Nc2ccc3ccccc3c2)C2(CCCCC2)O1 +O=S(=O)(NCc1ccccc1)c1ccc(F)cc1F +COC(=O)C1(NC(=O)Cc2ccc(F)cc2)CCCCC1 +Cc1cc2ccccn2c1-c1cnncc1Br +COc1ccc(-c2cc(CC(=O)Nc3cccnc3)no2)cc1OC +COc1ccc(CN2CC(C(=O)NC(C)C)CC2=O)cc1 +Cc1ccc(S(=O)(=O)NCC2CCCO2)s1 +Cn1cc(C(=O)Nc2ccc(NC(N)=O)cc2)c(C(C)(C)C)n1 +Cc1cccc(C(=O)OCCCn2nc3ccccn3c2=O)n1 +CCn1c(NC(=O)COc2ccc3c(c2)CCC3)nc2ccccc21 +CCN(CC(C)C#N)C(=O)c1cc(F)cc2[nH]cnc12 +CC(Sc1ncnc2c1cnn2C)C(=O)NC1CCCCC1 +CC(NC(=O)c1ccc(OCC(F)F)nc1)C(=O)NC(C)(C)C +COc1ccc(F)cc1NC(=O)N1CCC(c2noc(C)n2)CC1 +CC(C)c1nc(CN2CCNC(=O)CC2c2ccccc2)no1 +O=C(CN1CCCCC1=O)Nc1ccccc1OC1CCCC1 +CC(=O)c1cccc(NC(=O)Nc2ccc3[nH]c(=O)oc3c2)c1 +CCn1cc(CN(C)C(=O)c2cc(N)nn2C)cn1 +CCN(CC)C(=O)C(NC(=O)c1ccc(F)cc1)C(C)C +CSc1n[nH]c(N)c1C(=O)NCc1ccco1 +O=C1COc2cc(NCc3ccc(F)cc3)c(Cl)cc2N1 +CCCn1nnnc1NC(=O)COc1ccc(C)cc1 +COC(=O)CCC(=O)N1CCOc2ccc(F)cc21 +CSc1nnc(CNS(=O)(=O)c2ccc(Cl)cc2)n1C +COc1ccc(-c2noc(=O)n2Cc2ccccc2C#N)cc1OC +Cc1ccccc1C(=O)NCC(=O)NCCc1cccs1 +CN(C)C(=O)c1cc(C(=O)c2ccccc2F)c[nH]1 +O=C(NCCSc1ccccn1)c1cc(-c2ccccc2O)n[nH]1 +CC(C)(C)n1cc(C#N)c(NC(=O)c2scnc2C2CC2)n1 +CC(C)CCOC(C)C(=O)N(C)CC(=O)N(C)C +O=C(Cn1cnc2ccccc2c1=O)NCCOc1ccccc1 +CCc1nnc(NC(=O)Cc2ccc(C)s2)s1 +Fc1c(Cl)cccc1-c1nnc2sc(-c3cnccn3)nn12 +CCS(=O)c1ccccc1C(=O)NCC(C)(C)c1ccncc1 +NC(=O)c1ccsc1NC(=O)COc1ccc(-c2nnco2)cc1 +CC(=O)N(C)c1ccc(NC(=O)CNc2cccc(Cl)c2)cc1 +OCCN(CCO)c1ncnc2c1cnn2-c1ccccc1 +Cc1cc2c(=O)n(C)c(SCc3nc4ccccc4[nH]3)nc2s1 +NC(=O)COc1cccc(C(=O)N2CCCCC2Cn2cccn2)c1 +Clc1ccccc1C1CCN(c2nnc(C3CC3)o2)C1 +COc1ccccc1CCN(C)Cc1c[nH]nc1-c1cccs1 +O=C(COCC1CC1)N(Cc1ccco1)c1ccc(F)cc1F +Cn1cccc1C(=O)N1CCC2(CC1)CCN(c1ncccn1)C2 +O=C(NCCc1cscn1)Nc1ccc(-c2csnn2)cc1 +CCc1cccc(C)c1NC(=O)CNc1c(C)cccc1C +CC(NC(=O)NC1CCCCNC1=O)c1ccc(-n2ccnc2)cc1 +CCCNC(=O)CCN1C(=O)C(C)(C)c2ccccc21 +CN(C(=O)c1ccc(S(C)(=O)=O)cc1)c1ccc2ccccc2c1 +CCc1nnc(NC(=O)N(Cc2ccccc2)Cc2ccco2)s1 +Cc1cc(C(=O)Cn2nnc3ccccc3c2=O)c(C)n1C +CCc1onc(C)c1NC(=O)N1CCC(c2ccc(OC)cc2)C1 +O=c1nccc(SCc2ccccc2Cl)[nH]1 +COC(=O)N1CCCN(S(=O)(=O)c2ccc(C)cc2F)CC1 +CC(=O)Nc1cccc(NC(=O)c2ccc(Cl)c(Cl)c2)c1 +COC(=O)C(NC(=O)c1ccccc1)C(O)c1ccccc1F +CCOc1c(O)ccc2c1C(c1ccccc1)NCC2 +CC(=O)Nc1cccc(NC(=O)CC2CCCC2)c1 +CCn1c(C)cc(C(=O)NCCOc2cccc(F)c2)c1C +CCCNC(=O)c1cccc(CNC(=O)c2cccc3cn[nH]c23)c1 +CC(=O)c1ccc(NC(=O)c2c(C)nn(-c3ccccc3)c2C)cc1 +CN(Cc1ccc2ccccc2c1)C(=O)c1ccncc1 +COc1ccc(F)cc1NC(=O)c1csc(S(N)(=O)=O)c1 +CNC(=O)c1ccc(NC(=O)NC2Cc3ccccc3C2)c(C)c1 +CCOC(=O)CCC(C)NC(=O)NC1COc2ccc(C)cc21 +CC(C)(CC1CCOCC1)C(=O)N1CCC(C(N)=O)c2ccccc21 +Cc1ccc(OCc2nc(C(=O)NC(C)(C)C(N)=O)cs2)cc1 +COc1ccc(OCc2nc(C#N)c(NCC(C)C)o2)cc1 +CC(C)c1cc(C(=O)Nc2ccc3c(c2)OCO3)no1 +CN(C)c1cc(OC2CCN(C(=O)c3ccsc3)C2)ncn1 +COc1ccc(C)cc1S(=O)(=O)N1CCC(C)CC1 +COC(=O)CSc1nnc(CCc2ccccc2)n1N +CCOc1ccc(NC(=O)N(C)CC(=O)Nc2ccccc2)cc1F +CCOC(=O)N1CCN(C(=O)c2ccccc2NC(=O)N(C)C)CC1 +Cc1ccccc1CNC(=O)c1cccc2cn[nH]c12 +Cc1nc(C)c(CNCc2ccc(F)c(C(F)(F)F)c2)s1 +CCn1cc(N2CC(C(=O)NCc3ccc(OC)cc3)CC2=O)cn1 +Cn1cc(S(=O)(=O)Oc2ccc(Cl)c3ccccc23)cn1 +Cn1c(N2CCCCCC2)c(C#N)c(=O)n(C)c1=O +C=C(C)CN(CC)C(=O)NCCC1(C)OCCO1 +CC(C)C(=O)NCC1CCCN(c2ccc(Cl)cc2C#N)C1 +Cc1ccc(CCNc2ccnc(C(F)(F)F)n2)o1 +Cc1cc(C(=O)N2CCOC(c3nc(C(C)(C)C)n[nH]3)C2)c(C)s1 +O=C(OCc1ccsc1)c1cc(N2CCCC2=O)ccc1Cl +CCc1nnc2n1CCN(C(=O)c1cc3cc(F)ccc3[nH]1)C2 +O=C(Nc1ccc(-c2nc3ccccc3c(=O)o2)cc1)C1CC1 +O=C(NCc1ccc(F)c(Cl)c1)c1cncnc1 +Clc1ccc(-n2cccn2)c(NCc2cnc[nH]2)c1 +CC(C)NC(=O)c1cccn2c(-c3ccccc3F)nnc12 +CC(=O)c1ccccc1NC(=O)CSc1nnnn1C1CCCC1 +CCCNC(=O)CN1CCN(c2ncccn2)CC1 +O=C(c1ccncc1)N1CC2(CCN(c3ncccn3)C2)C1 +CN(CC(N)=O)S(=O)(=O)c1ccc(C(F)(F)F)cc1 +CCc1nnnn1CC(=O)Nc1cccc(Cl)c1 +Cc1ccc(C(C)NC(=O)Nc2cccn(C)c2=O)cc1F +Cc1cc(C(=O)CN2C(=O)c3ccccc3S2(=O)=O)c(C)n1C +CCCCS(=O)(=O)NCc1ccc(-n2cccn2)nc1 +Fc1ccc(Cl)cc1-c1cc(NC2CC2)ncn1 +Cc1ccc(OC(C)C(=O)Nc2cccc(C(N)=O)c2)cc1 +COc1ccccc1CC1CCCN1C(=O)c1cccnc1OC +CCc1nnc(NC(=O)Cc2cccc(F)c2)s1 +O=C(COC(=O)Cc1cccs1)NC1CCc2ccccc21 +CCOC(=O)NCCC(=O)N1CC(C)CC(C)C1 +O=C1OCCC1Sc1ncnc2sc3c(c12)CCC3 +Fc1ccc(NCc2c[nH]nc2-c2cccnc2)cn1 +Cc1ccc(CN(C(=O)c2cn3cccnc3n2)C2CCCC2)s1 +O=C(NCCCc1ccc(O)cc1)c1ccc(Cn2cnnn2)cc1 +COCCCOC1CN(C(=O)c2nccc3ccccc23)C1 +CCS(=O)(=O)N1CCCc2cc(C(=O)NCCOC)ccc21 +CCOC(=O)C(NCC(F)(F)F)c1c(F)cccc1F +CCOc1cc(C2NCCc3cc(F)ccc32)ccc1O +CC1CC(NC(=O)C(C)Oc2ccccc2Cl)CC(C)O1 +CCN(C(=O)CNc1cccc(C(=O)NC)c1C)C1CCCCC1 +Cc1sc2ncn3nc(-c4ccn(C)n4)nc3c2c1C +O=C(CN1CCOCC1)Nc1ncc(Cc2ccccc2F)s1 +Cc1cc(C)n2ncc(C(=O)NCCN3CCCCCC3=O)c2n1 +CNC(=O)c1ccc(=O)n(CC(=O)Nc2ccc(F)c(F)c2)c1 +CCOC(=O)CN(C(C)C)S(=O)(=O)N1CCCCC1C +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1c(F)cccc1Cl +O=C(Nc1cccc(-c2nc[nH]n2)c1)c1cc(-c2cccnc2)n[nH]1 +CC(N)C(=O)c1coc2c(Br)cccc12 +Cc1cc(C)c(C)c(C(=O)CCC(=O)NCc2ccco2)c1C +COc1c(Cl)cc(C(=O)NCC2CCC2)cc1Cl +CCOC(=O)N1CCN(c2nc(Cc3ccc(C)cc3)ns2)CC1 +Cc1ccc(C)c(S(=O)(=O)CC(=O)NCc2ccc(C)c(F)c2)c1 +COc1ccc(-c2nc3c4c(ncn3n2)CCC4)cc1 +COCc1ccccc1NCc1cc(OC)c2c(c1)OCCO2 +CC(=O)c1ccc2c(c1)CCN2Cc1ccc(OCC#N)cc1 +CCc1ccc(S(=O)(=O)N2CCC(CO)CC2)cc1 +Cc1cc(Cl)ccc1NC(=O)Cn1cnnn1 +Cc1cccc(N(C)Cc2cnc3ncccn23)c1 +C#Cc1cccc(NC(=O)NCc2ccc(C(=O)OCC)o2)c1 +CCCCOc1ccccc1CNc1cc(C)on1 +Cc1ccc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)c(N)c1 +CNC(=O)c1nccnc1CC1CCCN(C(C)=O)C1 +O=C(NCC(CO)Cc1cccs1)c1ccc(-n2ccnc2)cc1 +CN(C1CCC(C)(C)CC1)S(=O)(=O)N1CCOCC1 +Cc1occc1C(=O)NC1CCN(c2ccccc2Cl)C1=O +CCCC(NC(=O)C1CCOCC1)c1ccccc1 +Cc1ncncc1NCc1csc2ccccc12 +O=C1CC(C(=O)N2Cc3cnn(CCO)c3C2)c2ccc(F)cc2N1 +CC(NC(=O)NCCOc1ccc2c(c1)OCO2)c1ccccc1 +CCCC(=O)Nc1cccc(NCc2n[nH]c(=O)[nH]2)c1C +O=C(COc1ccccc1F)N1CCCC(c2ccn[nH]2)C1 +N#Cc1cccc(NC(=O)CCNC(=O)c2ccc(F)cc2F)c1 +COc1cc(C(=O)Nc2nccs2)ccc1OC(F)F +Cc1cc(C)n(CC(=O)Nc2ccccc2C(F)(F)F)n1 +Cc1cccc(N2CCN(C(=O)Nc3nncs3)CC2)c1C +Cc1cc(N2CCCC2=O)ccc1S(=O)(=O)N1CCCC1 +O=C(CCn1cnc2ccccc2c1=O)Nc1nnc(C2CC2)s1 +CC=Cc1ccc(OCC(=O)NCC(C)C)c(OC)c1 +COc1ccccc1C(C)NC(=O)c1n[nH]c2ccc(C)cc12 +CC1CCCC(NC(=O)N2CCC(CC(N)=O)CC2)C1 +CCCn1nc(C(=O)N2CCOC(c3nc(CC)n[nH]3)C2)ccc1=O +Cc1cc(NC(=O)CCCCCc2cccs2)[nH]n1 +CNC(=O)c1nnsc1NC(=O)Nc1ccccc1 +O=c1oc2ccc(Br)cc2cc1-c1ccccn1 +O=C(NCCCOCC1CC1)Nc1ccc(Br)cc1F +CCc1nc2ccccc2n1CC(=O)NCCc1ccccc1OC +COCCCC(=O)N1CCc2cc(F)ccc2C1 +O=C(CCC(=O)c1ccccc1)OCc1cccnc1 +CC1CCCC(C)N1C(=O)Cn1ncc(Cl)c(Cl)c1=O +CCc1nc2n(n1)CCCC2NC(C)c1cc(F)ccc1F +CC(C)n1nnnc1-c1cccc(C(=O)Nc2ccccc2)c1 +CC(=O)NCCNC(=O)NC1CCc2c(F)cccc21 +COc1cc(C(C)NC(=O)NC2CC2)ccc1OC1CCCC1 +CC1CN(CCCNC(=O)Nc2cn[nH]c2)CC(C)O1 +CC(Sc1nnc(C(C)(C)C)n1N)C(=O)NC1CCCCC1 +CC(=O)Nc1cccc(-c2nccn2CC2CCCO2)c1 +COc1cc(OC)cc(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)c1 +COc1ccccc1OCC(=O)Nc1ncccc1Cl +Cc1ccc(S(=O)(=O)NCCC(=O)Nc2cc(C)cc(C)c2)cc1 +CC(C)CCNc1ccc2nnc(CCC(=O)N3CCOCC3)n2n1 +CN(Cc1cnn(C)c1)C(=O)COc1nnc(-c2ccccc2)o1 +O=C(NC1CCCC2(C1)OCCO2)c1cncc(Br)c1 +O=S(=O)(Nc1ccccc1CO)c1cc[nH]c1 +COc1ccc(CCOc2ccc(N)cn2)cc1F +c1ccc(-c2cnn3cc(CN4CCOC5CCCCC54)cnc23)cc1 +O=C(NCC1CC1)C1CCN(c2cccc(Br)c2)C1=O +CCCn1cc(NC(=O)Nc2cnccc2C)cn1 +Cn1nc(C(=O)NCc2cccc(Br)c2)c2ccccc21 +CCOC(=O)c1nc2cc(Cl)ccn2c1CC#N +O=C(CCCCCc1cccs1)Nc1ccnc2ccnn12 +C=CCNC(=O)C1CCCN(S(=O)(=O)N(C)C)C1 +O=C(c1ccc(N2CCCCC2)cc1)N1CCCC1 +Cc1cc(C)c(O)c(C(=O)NCCCc2c(C)noc2C)c1 +Cc1ccccc1C(=O)Nc1cccc2cnccc12 +Cc1ccc(NC(=O)CCN2CCOC2=O)c(O)c1 +COC(=O)NCC1CCN(c2ncccn2)CC1 +CSc1nc2c(c(Nc3ccc(S(N)(=O)=O)cc3)n1)CCC2 +Cc1cccc(C(Nc2nccc(-c3ccc(C)nc3C)n2)C2CC2)n1 +O=c1[nH]c(Nc2ccccc2)nc2nccc(-c3cccnc3)c12 +CC(=O)Nc1ccc(O)c(C(=O)NC2CCc3ccccc32)c1 +Cc1cc(C)n(Cc2ccc(C(=O)Nc3ccc(F)c(C#N)c3)cc2)n1 +CCN1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1 +CCOc1ncccc1NC(=O)C1CC(=O)N(Cc2ccccc2)C1 +CN1C(=O)C(C)(C)c2cc(C(O)CCCO)ccc21 +O=C(Nc1ccc(OCC2CC2)cc1)c1cnc2[nH]ccc2c1 +CCS(=O)(=O)c1ccccc1NC(=O)c1cccc(OC)c1 +NC(=O)C1CCCN(c2ccc(NC(=O)C3CCCC3)cn2)C1 +COc1ccc(C)cc1NC(=O)COC1CCCCC1 +CCN(C)C(=O)c1nn(-c2ccccc2F)c(C)cc1=O +CCCOc1ccc(NC(=O)c2cc(C)no2)cc1Cl +Cc1cc(NC(=O)CSc2ccccc2C)n(C)n1 +COc1ccc(CC(=O)Nc2ccc(F)c(N)c2)cc1OC +Cn1ccc(C(=O)NC2CCOc3ccccc32)cc1=O +C#CCN1CCN(C(=O)NCc2csc(N(C)C)n2)CC1 +CN(Cc1ccc(F)cc1)C(=O)CSc1ccc(C#N)cc1 +Cc1nc2cc(NC(=O)c3cc4cnn(C(C)C)c4nc3C)ccc2o1 +Cc1ccc(CC(=O)N(C)c2cc(C#N)c3ccccc3n2)cn1 +COCCCNC(=O)Nc1cc2c(cc1Br)OCCO2 +CC(C)(C)C1CCN(S(=O)(=O)N2CCOCC23CCC3)CC1 +Cc1cc(C(=O)N2CCC(C)Sc3ccccc32)c(C)o1 +COc1ccc2c(C)cc3nnc(SCCCC#N)n3c2c1 +COc1ccc(C(C#N)NC(=O)c2cccc(CC#N)c2)c(OC)c1 +COc1ccc(S(=O)(=O)N2CCC(O)C2Cc2ccncc2)cc1 +CC(C)c1ccc(C2CCCN2C(=O)c2ccn(C)c(=O)c2)cc1 +Cc1ccc(C)c(OC(=O)CCn2c(=O)[nH]c(=O)c3ccccc32)c1 +CCOc1cc(C(=O)Nc2cc(OC)ccn2)ccc1OC +Cc1nc(CC(=O)NCc2noc(-c3cccs3)n2)cs1 +CC1(C)Cc2c(cnn2-c2ccc(F)cc2)C(NC(=O)C2CCC2)C1 +Cc1ccc(CNC(=O)CC(C#N)c2ccccc2F)cc1 +CCc1cccc(NC2C(=O)Nc3cc(F)ccc32)c1 +COc1ccc(F)cc1S(=O)(=O)NCCc1ccoc1 +CCOC(=O)Cn1cnc2c(cnn2-c2cccc(Cl)c2)c1=O +Cn1cccc(C(=O)NCC(O)c2ccc3c(c2)CCO3)c1=O +O=C(C1CC1c1cccc(F)c1)N1CCCC1c1noc(C2CC2)n1 +CCN(C(=O)COC(=O)c1c(C)nsc1NC)c1ccccc1 +CCOC(=O)C(NC(C)=O)(Nc1ccccc1)C(F)(F)F +CC(NC(=O)Nc1ccccc1Cl)c1nc[nH]n1 +CC(NC(=O)c1cc2ccccc2cc1O)C(N)=O +CC(=O)N(C)CCc1noc(-c2cc3cc(C)ccc3[nH]2)n1 +c1ccc(CNCCc2nc(-c3cccs3)cs2)nc1 +Cc1ccnc2nc(C(=O)NCC(C)(O)c3ccsc3)nn12 +Cc1cccc(C(=O)NCc2ccnc(-n3cccn3)c2)c1 +CC1CCC(C)N(C(=O)c2cccnc2OCC(F)F)C1 +CCc1ccc2[nH]c3nc(SCC(=O)NCCOC)nnc3c2c1 +O=C(CN1CCN(C(=O)c2cccs2)CC1)Nc1nncs1 +COc1ccccc1Nc1nc(-c2ccncc2)cs1 +O=C(OCCNc1cccnn1)c1sccc1-n1cnnn1 +CC(C)(C)c1nc2cc(NC(=O)N3CCOCC3)ccc2o1 +CCOc1cc(CNc2cc(F)ccc2OC)ccc1OC +Cc1cc(C)c(NC(=O)CNc2c(C)cccc2C)c(C)c1 +CCC(NC(=O)CNC(=O)c1ccc(OC)cc1)c1ccc(C)cc1 +O=C(Cn1cnnn1)Nc1ccnn1C1CCCCC1 +Cn1ccnc1Cn1c(C2CC2)nc2ccc(F)cc21 +CC(NC(=O)CSc1ccc(F)c(F)c1)c1ccncc1 +O=C(CCn1c(=O)oc2ccccc21)Oc1cccc2[nH]ncc12 +Cc1cccc(NC(=O)CCNC(=O)Nc2nnc(C(C)C)s2)n1 +CC(C)n1cc(Br)cc1C(=O)N(C)CC1CC1 +CC(C)(O)c1nnc2ccc(-c3ccccc3)nn12 +CCCn1c(C)nnc1SCC(=O)NCc1ccccc1C +CC1CCCN(C(=O)NCc2ccc(-n3ccnc3)c(F)c2)CC1 +Cc1nc(NC(=O)CSc2nnnn2C2CC2)sc1C +CN(Cc1cccc(O)c1)C(=O)Nc1ccccc1-n1cccn1 +N#CC1(N2CCCCC2)CCCOc2ccccc21 +O=C1CC(c2ccccc2)=Nc2cc(Cl)ccc2N1 +CCc1nn(CCO)c(CC)c1Oc1cc(C#N)cc(C#N)c1 +Cc1cc(C)cc(NS(=O)(=O)c2ccc3c(c2)CCC(=O)O3)c1 +COCc1cc(NC(=O)c2cnc(C3CCCO3)s2)ncn1 +COC(=O)c1ccoc1COC(=O)c1cn(C)c2ccccc12 +O=C(CN1CCOC(CCc2ccccc2)C1)Nc1nccs1 +Cc1nc(NCCC#N)cc(-c2cncc(-c3cccs3)c2)n1 +C=CCn1c(SCCn2cccn2)nc2ccccc2c1=O +CC(=O)Oc1ccc(C2OC(=O)c3ccccc3N2C(C)=O)cc1 +Cc1cc(C(=O)N(Cc2ccccn2)C(C)C)c(C)n1-c1cccnc1 +Cc1ccc(C(O)CNC(=O)OC(C)(C)C)cc1 +Cc1cccc(NC(=O)N2CCCC2c2c(C)noc2C)c1 +Cc1ccc(-c2cc(C(=O)N3CCCCCC3c3ccco3)[nH]n2)o1 +CC1CN(CCCNC(=O)N2CCc3ccccc32)CC(C)O1 +CCNc1ccc(S(=O)(=O)NCC(F)(F)F)cc1 +COc1cc(OC)cc(C(=O)Nc2ccccc2NC(C)=O)c1 +CCC(=O)N1CCN(Cc2c(C)nn(-c3ccc(F)cc3)c2C)CC1 +CC(Sc1ccccc1)C(=O)NCC1CN2CCCCC2CO1 +N#CC(CN1CCOCC1)c1ccc(Cl)cc1Cl +CCOc1ccc(NC(=O)NC2CCCC2C(=O)OC)c(C)c1 +C=CCN1CCC2(CCC1=O)CN(C(=O)N1CCCCC1)CCN2C +O=S(=O)(Cc1noc2ccccc12)N1CCOCC1 +CCCCN(C)S(=O)(=O)NC(C)c1c(C)noc1C +CC(C)(C)C(=O)Nc1cccc(OCC(=O)Nc2ccc(O)cc2)c1 +Cc1cc2occ(CC(=O)NCc3nccc(N)n3)c2cc1C +CCCN1CCCC2(CCN(c3noc(-c4ccccc4)n3)C2)C1=O +CC(C)C(NC(=O)c1ccc2cncn2c1)C(=O)N1CCCCC1 +CS(=O)(=O)N1CCC(c2nc3ncccc3[nH]2)C1 +COc1ccc(CN(C(=O)Cc2ccc(O)cc2)C2CC2)cc1 +Cc1ccccc1NC(=O)CSc1nnc(N)n1C +Cc1ccc(NC(=O)NC(C)c2cnn(C)c2)cc1-n1nnnc1C +CC(C)c1nc(S(=O)(=O)N2CCCC(Cn3cncn3)C2)c[nH]1 +C=CCOC(C)C(=O)NC1(c2noc(C)n2)CCCC1 +Cc1cnc(N2CCc3c(C(=O)N4CCCC4)n[nH]c3C2)nc1 +CN(C)c1cc(F)c(C(=O)NCC(F)(F)F)cc1F +NC(=O)Cn1cc(NC(=O)NCCc2ccc3c(c2)OCCO3)cn1 +COc1ccc(S(N)(=O)=O)cc1NC(=O)c1ccc(C(C)C)cc1 +CC(O)CNC(=O)c1cc(CCc2ccccc2)no1 +Fc1ccc(OCC2CCCN(c3cnccn3)C2)cc1 +COc1ccc(C)cc1CC(=O)NC1(C#N)CCOCC1 +O=C(N1CCCC1)N1CCC2(CC1)CN(c1ncc(F)cn1)CCO2 +Cc1sc2nc(COC(=O)c3ccccc3O)[nH]c(=O)c2c1C +Cc1cc(NC(=O)CCC(=O)c2ccc(-c3ccccc3)cc2)n(C)n1 +Cc1nc(C2CCCN(C(=O)CCn3ccnn3)C2)sc1C +CCOC(=O)CN(CC)C(=O)c1cc(N)cn1C +Cc1cc(=O)n(CCOc2ccc(Br)cc2)cn1 +COCC(=O)N1CCC2(CCCC(=O)N2Cc2cccc(F)c2)CC1 +COc1ccc(CC(=O)Nc2ccccc2N2CCOCC2)cc1 +CC(=O)N1CCN(C2C(O)c3ccccc3OC2(C)C)CC1 +CCc1cc(Cn2nc(C)cc2C#N)ccc1OC +CC(=O)C(C)CCCCC(=O)NC1c2ccccc2CC1O +O=S(CCN1CCOC(Cn2cncn2)C1)c1ccccc1 +CC1CN(C(=O)c2cc(NC(=O)c3cccs3)n(C)n2)CC(C)O1 +CCC(C)n1c(C)cn2c3c(=O)n(C)c(=O)n(C)c3nc12 +COCCOC(=O)c1oc2c(c1C)C(=O)CC(c1ccco1)C2 +CC(=O)N(C)c1ccccc1NC(=O)c1c[nH]c2cccc(F)c12 +CCN(CCNC(=O)c1cc(C)ccc1O)C(=O)OC(C)(C)C +CC1CCCCN1C(=O)NCc1ccc(-n2ccnc2)c(F)c1 +CCNS(=O)(=O)CCCOc1ccc2c(c1)OCO2 +Cc1ccc[nH]c1=NS(=O)(=O)c1c[nH]c(C(=O)N2CCCC2)c1 +Cc1cccc(CNC(=O)NCCc2csc(C(C)C)n2)c1 +CS(=O)(=O)N1CC(C(=O)NCCOc2ccccc2)C1 +O=C(NCc1cccnc1)c1ccc2ccccc2c1 +CCc1ccc(OCC(=O)Nc2ccc(-n3cnnn3)cc2)cc1 +COc1ccc2cc(C(=O)Nc3ccccc3-n3cccn3)[nH]c2c1 +NC(=O)NCC(=O)NCc1ccc(-n2ccnc2)cc1 +COc1ccc(N(C(C)C2CC2)S(=O)(=O)CC2CCOC2)cc1 +CCn1c2ccccc2n2c(SC(C)C)nnc12 +Cc1ccc(-c2nc(Cn3ccnc3-c3ccccn3)cs2)o1 +CCCCn1nc(C(=O)Nc2ccc(S(C)(=O)=O)cc2)ccc1=O +COc1cccc(C(=O)OC2CCCC2OC)c1 +Cc1nn(Cc2ccc(C(=O)NC3CC3)o2)c(C)c1Cl +COc1ccc(F)cc1C(O)CNC(=O)C1CCCCC1 +O=C(c1cscn1)N1CCc2c(O)nc(-c3cnccn3)nc2C1 +Cc1ccc(SCC(=O)N2CC(C)OC(C)C2)cc1C +O=C(CC1CC1)NCc1cn2c(n1)CN(S(=O)(=O)C1CC1)CC2 +CCC(C(=O)NCc1c(OC)ccc2ccccc12)N1CCCC1=O +O=C(NCc1ccccc1F)C1(c2cc(-c3cccs3)on2)CC1 +CN(CC(=O)N1CCOCC1)C(=O)c1ccc(OCC2CC2)cc1 +CN(C(=O)CNc1cc2c(cc1Cl)NC(=O)CO2)c1ccccc1 +Cc1ccccc1CN1C(=O)C(C(C)C)Oc2ccc(N)cc21 +Cn1ncc2c(N3CCC(C(=O)N4CCOCC4)CC3)ncnc21 +CCC(=O)Nc1ccc(C(C)NC(=O)NCc2cc(C)oc2C)cc1 +CN(Cc1nc2ccccc2c(=O)[nH]1)c1ccc(C#N)cn1 +CCOC(=O)c1nn(C)c2c1CN(Cc1c(F)cccc1F)CC2 +Cc1nn(-c2ccccc2)c(CN2CCOCC2C)c1C#N +N#Cc1ncn(Cc2ccc(Cl)c3cccnc23)c1C#N +CC(C)c1cccc(NC(=O)Cn2nc(-c3cccs3)oc2=O)c1 +CN(C)C(=O)CN(C)S(=O)(=O)c1ccc(O)c(N)c1 +CC(C)(C)CC(=O)Nc1nc(C(F)(F)F)cs1 +CC1CCCN(S(=O)(=O)NC2CCN(c3ccccc3)CC2)C1 +Cc1nc2c(c(=O)[nH]1)CCN(C(=O)c1ccccc1-n1cccn1)CC2 +CSc1nnc(SCC(=O)Nc2ccc3c(c2)CCC3)s1 +CCC1Nc2ncccc2-n2cnc(C(C)(C)C)c21 +COc1ccc(-c2c(C#N)nnn2-c2ccc(O)cc2)cc1 +Cc1ccc(-n2nnnc2SC2CC(C)OC2=O)cc1 +Cc1nnc(SCC(=O)Nc2c(C)cccc2C)o1 +CCCCn1c(N)c(N(Cc2ccco2)C(=O)CC)c(=O)[nH]c1=O +COCCn1nc(-c2ccccc2OC)cc(CO)c1=O +COc1ccc(S(=O)(=O)NCc2ccccc2-n2cccn2)cc1 +Cc1cc(F)ccc1NC(=O)c1nc2nccc(C)n2n1 +CC(Cn1cc(Cl)cn1)C(=O)Nc1cc(-c2ccccc2)n[nH]1 +c1ccc2c(c1)OC1(CCC1)CC2NCC1CN2CCCC2CO1 +CCN(CC(F)(F)F)CC(C)(O)c1ccccc1 +CCCC(C)C(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1 +Cc1ccc(C(=O)N2CCc3ccccc3C2)c(O)c1C +NC(=O)CSc1ncnc2c1cnn2-c1ccc(F)cc1 +Cc1nc(C)n(-c2ccccc2NC(=O)NC(C)(C)C)n1 +Cc1c(C#N)c2nc3ccccc3n2c(=O)c1=CN1CCCC(C)C1 +CN1CC(NC(=O)CCOc2cc(Cl)cc(Cl)c2)CCC1=O +Cc1csc(C(C)NC(=O)Nc2ccc(F)cc2OCC2CC2)n1 +CN(C)c1cnnc(N2CCN(C(=O)CCc3ccccc3)CC2)c1 +Cc1ccc(N2CCC3OCCC3(C(=O)N3CCCC3)C2)nn1 +CC(=O)N1CCc2ccc(C(O)c3ccccc3C)cc2C1 +CCCCCCNC(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +c1nc(N2CCOC3CCCCC32)c2nc[nH]c2n1 +Cc1ccsc1C(=O)NCC(=O)Nc1ccc(Cl)cc1 +C=CCOc1ccc(C(=O)Nc2cccnc2)cc1 +Cc1ccc(C(=O)CCC(=O)NC(C)c2nnc3n2CCC3)cc1C +CC(=O)C1(c2ccccc2)CCN(C(=O)CCCc2cn[nH]c2)CC1 +CC1CCCCC1NS(=O)(=O)N(C)CCC#N +CC(C)CC1(CNC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)CCCC1 +CCCCNC(=O)c1onc(-c2ccc(F)cc2)c1N +CC1CC1c1ccc(CCC(=O)N(C)Cc2nc3ccccc3[nH]2)o1 +CCn1cnnc1CNC(=O)c1cc(-c2cccs2)n[nH]1 +COC(=O)c1cc(-c2ccccc2)cc(N)c1OC +CCc1ccsc1C(=O)Nc1cc(S(C)(=O)=O)ccc1Cl +CCC(NC(=O)c1cc(Cl)ccc1N)C(C)C +COc1ccccc1-c1noc(-c2cn3cccnc3n2)n1 +Cc1noc2nc(C3CC3)cc(C(=O)OC(C)C(N)=O)c12 +COC(=O)NCC(=O)Nc1nnc(C(F)(F)F)s1 +C#Cc1cccc(NC(=O)CN(C)C(=O)C2CCC2)c1 +COc1ccc(-c2ccnc3nc(C(C)C)nn23)cc1 +CC(C)C1C(=O)NCCN1Cc1csc(Nc2ccccc2)n1 +CCc1onc(C)c1NC(=O)C(C)Oc1ccc(OC)cc1 +CC(Oc1ccc(Cl)cc1)C(=O)N(C)C(C)c1cccnc1 +Cc1ccnc(NC(=O)C2CCN(C(=O)NC3CC3)CC2)c1 +CCCn1ncc(C(=O)NC2(Cc3ccccc3C)CC2)c1C +CCn1c(C)nn(-c2nc3c(Cl)cccc3s2)c1=O +Cc1oc(-c2ccccc2)nc1CC(=O)Oc1ccc2cn[nH]c2c1 +CS(=O)(=O)c1ccc(OCc2cccc(F)c2)cc1 +CC(C)C(NC(N)=O)C(=O)NCC1CN2CCCCC2CO1 +CC(O)(CC(=O)NC1CC(=O)N(CC(F)(F)F)C1)c1ccccc1 +CCOCCCNC(=O)c1cc2c(nc1N)CCCCC2 +O=C(c1cc(Cl)c2c(c1)OCCO2)N1CCCCC1 +Cc1ccc2ncc(C(=O)Nc3c(-c4ccc(F)cc4)ncn3C)n2c1 +Cc1ccc(-n2nnnc2SCCCc2cnn(C)c2)cc1 +Cc1nc2cc(NC(=O)c3cnn(-c4ccccc4)c3C)ccc2s1 +Nc1nnnn1NCc1ccccc1C(F)(F)F +c1cncc(CNCCc2ccc3c(c2)OCCO3)c1 +N#CCn1c(=O)n(CCc2ccccc2)c(=O)c2sccc21 +CC(=O)c1c(C)[nH]c(C(=O)OCn2nnc3ccccc3c2=O)c1C +CC(Sc1nnnn1-c1ccccc1)C(=O)c1ccc(F)cc1 +CCOC(=O)COc1cccc(NS(C)(=O)=O)c1 +CCCc1cc(=O)[nH]c2nnc(SC(C)C)n12 +Nc1cc(Cl)ccc1C(=O)NCC1CCCO1 +CN(C)C(=O)C1CCCN1C(=O)COc1ccccc1C#N +CCCNc1nnc(SCC(=O)Nc2cccc(C)c2)s1 +COc1cc(CC2CN(C(=O)NC3CC3)C2)cc(OC)c1 +CC(=O)Nc1c(C)c(C)cc2c1C(C)CC21CCCCC1 +O=C(COC(=O)c1ccccc1F)Nc1c(F)cccc1F +Cc1cc(C(=O)CCN2CCOCC2)c(C)cc1OC(C)C +NC(=O)c1nc(-c2ccccc2)nc2c1[nH]c(=O)n2C1CCCCC1 +Cc1cccc(CNC(=O)Nc2ccccc2SC(C)CC#N)c1 +CCC(C)c1ccc(C(=O)CCN2CCC(=O)CC2)cc1 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+CCN(CC)C(=O)c1ccc(NC(=O)C2CC2(Cl)Cl)cc1 +CCN(CCOc1ccc(N)cn1)c1ccccc1 +CCNC(=O)c1cc(NC(=O)c2ncoc2CC)nc2ccccc12 +CCOCCC(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1 +CCCOCCNC(=O)c1c(C)noc1-c1cccc(F)c1 +COC(=O)c1cc(-c2cc(F)ccc2OC)nn1-c1ccccn1 +CN1C(=O)CN(Cc2noc(C3CCCC3)n2)C(=O)c2ccccc21 +COCc1nnc(NC(=O)C2(n3cnnn3)CCCCC2)s1 +Cc1cccc(NC(=O)c2cc(C(N)=O)cn2C)c1 +Cc1ccc(C(=O)NCC(=O)NC(C)(C)C)c(=O)[nH]1 +CN(C(=O)Cn1nnc2ccccc2c1=O)C1CCCc2ccccc21 +Cn1c(C(=O)NCC2=NC3=CC=CCC3=N2)cc2sccc21 +CC(=O)c1c(C)[nH]c(C(=O)OCc2nc(N)nc(N(C)C)n2)c1C +CC(C)(C)OC(=O)N1CCC(n2cc(C#N)c(N)n2)C1 +CN1CCN(C(=O)C2CC(=O)N(c3ccc(F)c(Cl)c3)C2)CC1 +CNC(=O)Cn1c(CO)cnc1SCc1ccc(C)cc1 +O=C(CNC(=O)Nc1cccc(Cn2cccn2)c1)NC1CC1 +O=c1[nH]c(CN(Cc2cccs2)C2CC2)nc2ccccc12 +CC(=O)c1ccc(NC(=O)c2cc(C#N)c[nH]2)cc1C +CN(Cc1ccncc1)C(=O)NCc1cccc(F)c1 +CCc1ccc(-c2nc(-c3ccnc(OC)c3)no2)o1 +CCc1cccc(CC)c1NC(=O)C(C)c1nonc1N +CC(C)CNC(=O)NCc1cccc(NC(=O)C2CCCO2)c1 +O=C(c1cccs1)C1CCN(C(=O)C2CCCO2)CC1 +COC(=O)c1cc(C)ccc1S(=O)(=O)CC(C)C +CCn1c(C2CCN(C(=O)Nc3c(C)noc3C)CC2)n[nH]c1=O +CCOC(=O)C(NC)c1c(Cl)cccc1Cl +c1ccc(-c2ccc(SCCC3OCCO3)nn2)cc1 +COc1ccc2c(cnn2-c2ncccc2C#N)c1 +CC(C)(C)OC(=O)N1CCCN(C(=O)C2CC2)CC1 +CC(=O)Nc1ccc(SCC(O)COc2c(C)cccc2C)cc1 +COc1ccc2c(c1)c(CO)cn2C(=O)OC(C)(C)C +CC(C)(C)NC(=O)c1ccc2nc3ccccc3c(=O)n2c1 +Cc1ccc(OC(=O)Cn2c(=O)cnc3ccccc32)cc1 +COc1ccc(-c2cc(=O)n(CCNS(C)(=O)=O)cn2)cc1 +O=C(NCc1nc(Cn2ccnc2)cs1)c1ccccc1 +CC(=O)c1cccc(NC(=O)c2ccc(Cl)cc2-n2cnnn2)c1 +Cc1ccsc1C(Cc1ccccc1)NC(=O)C(C)NC(N)=O +COc1ccccc1Cn1cnc2cc(F)ccc2c1=O +c1ccc2nc(N3CCC(c4cn[nH]c4)CC3)cnc2c1 +Cn1cc(C#N)cc1C(=O)OCc1cccnc1-n1cccn1 +CC(C)C(C)(C#N)NC(=O)COC(=O)Cc1cccs1 +CC(C)(C)C(=O)N1CCCC(C(=O)NC2c3ccccc3CC2O)C1 +CCc1cc(C)c(C(=O)NCc2ccnc(OC(C)(C)C)c2)o1 +CC(=O)N1CCN(Cc2nc(-c3ccc(C)s3)cs2)CC1 +Cc1ccc(CN(C)c2nc3ccccc3s2)o1 +O=C(Nc1ccc(-n2cnnn2)cc1)C(c1ccccc1)n1cccc1 +CCC1CCCN(C(=O)CCc2nc(-c3cccnc3)no2)C1 +CCC(C)NC(=O)c1ccc(NC(=O)N2CCCC(C)C2CO)cc1 +Cc1ccc(OCC(=O)NC2(C#N)CCCCC2)cc1 +Cc1cc(CN2CCN(C(=O)NCc3nc(C)cs3)CC2)on1 +CCN(CC)S(=O)(=O)c1cc(C(=O)NC)ccc1OC +O=C(Nc1ccccc1SCc1ccccc1F)c1ccnnc1 +CCC(C)NC(=O)C(C)NCc1cc(F)c(F)c(F)c1 +CC(C)N(CCC#N)S(=O)(=O)CCc1ccncc1 +N#Cc1cc2c(nc1N1CCC(C(=O)N3CCCC3)CC1)CCCC2 +Cc1cc(C)n2nc(C(=O)Nc3ccc(F)cc3F)nc2n1 +CCOc1ccc(-c2cc(CO)c(=O)n(C)n2)cc1CC +CCCn1nc(C(=O)OCc2nc(C)no2)ccc1=O +CCn1c2cc(C)oc2c2cnn(CC(=O)NC3CC3)c(=O)c21 +CC(C)N(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccncc1F +CCN(C)C(C(=O)N1CCCN(C(=O)OC)CC1)c1ccccc1 +Cc1c(C(=O)N2CCC(C(O)c3ccccc3)CC2)cnn1C +CN(CC(O)C1CC1)C(=O)NC1CC2(CCC2)Oc2ccccc21 +O=C(Nc1ccn(CC(F)F)n1)c1ccc2c(c1)OCO2 +O=C(Nc1nnc2n1CCCS2)C1CCCC1 +O=C(COCC1CC1)Nc1ccc(-n2ccnc2)nc1 +C#CCOC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +CCOC(=O)C1CCCN(c2ccc(F)cc2C(C)=O)C1 +CNC(=O)CNc1ccc(NC(=O)c2cccc(C)c2)cc1 +CN(C)C(=O)COc1ccc(Br)cc1Br +CCCCc1cc(NC(=O)C(C)Oc2ccc(C#N)cc2)[nH]n1 +CC(Oc1ccc(Br)cc1F)C(=O)N1CCNC(=O)C1 +CCn1cc(C(C)NC(=O)c2c(N)cnn2CC)cn1 +CCc1cccc(NC(=O)c2cc(OC)c(OC)c(OC)c2)c1 +Cc1ccc(NC(=O)CSc2nnc(C)n2N)cc1Cl +COc1ccccc1CN1CC(C(=O)NCC(F)(F)F)CCC1=O +Cc1cc(C)n2nc(NCC=Cc3ccccc3)nc2n1 +COc1ccc(C(=O)NCCSc2ccccc2)nn1 +COc1ccccc1CC(=O)Nc1ccc(C)cc1O +COC(=O)C1CC2CCC(C1)N2C(=O)OC(C)(C)C +CC(C)Oc1ccc(C(=O)Nc2nnc3n2CCS3)cc1 +CC1CCN(C(=O)c2ccc(C#Cc3ccccc3)cc2)CC1 +COc1ccc(S(=O)(=O)N2CC(C)OCC2C)cc1F +CCS(=O)(=O)N1CCCC2(COCCN(c3nnc(C)o3)C2)C1 +COc1cccc(S(=O)(=O)NCc2cc(C)oc2C)c1 +Cc1cc(NC(=O)N2CCOC3(CCCC3)C2)n(CCC(C)C)n1 +CC(Nc1nc2ccccc2s1)C(=O)NCc1ccccn1 +N#Cc1ccc2c(c1)OC(=O)C(C(N)=O)C2c1ccncc1 +COCCNC(=O)Cn1nc(C)n2c(cc3ccccc32)c1=O +CCC1CCCN(C(=O)c2cc(S(N)(=O)=O)ccc2Cl)C1 +Cc1ccc(OCC(=O)NCCNC(=O)c2ccc(C)nc2)cc1 +NC(=O)c1ccccc1NC(=O)CCCn1cccc1 +Cc1cccc(NC(=O)CSc2nc(C)cs2)c1 +CCN(CC)C(=O)N1CCCC(c2ncncc2S(C)(=O)=O)C1 +O=S1(=O)CCCN1Cc1coc(-c2ccc(F)cc2)n1 +Cc1ccc(-n2nnc(C(=O)Nc3ccccn3)c2C2CC2)cc1 +CCOc1cc(C(=O)OCc2ccoc2C)ccc1OC +CCc1nc(CN(C)C(=O)c2ccccc2Cn2cncn2)cs1 +Cc1nn(C)c(=O)c(C(=O)N2CC(C)c3ccccc32)c1C +CCn1c(SCC(=O)N2CC(C)CC(C)C2)nnc1-c1ccco1 +COc1cc(-c2nc(C)c(CCO)s2)ccc1F +CCCn1c(SCc2cccc3c2OCCO3)n[nH]c1=O +COc1ccccc1CN(C)C(=O)c1cccs1 +CC(=O)N1CC(C(C)C)Oc2ccc(S(N)(=O)=O)cc21 +COc1ccccc1OCc1nc(C(C)(C)C)c(CO)s1 +Cc1cc(C)cc(NC(=O)c2ccc(C(N)=O)cc2)c1 +Cc1cc(C)cc(C(=O)N(C)Cc2ccccc2F)c1 +Cc1cc(C)c(C(=O)N(C)Cc2ccc(C)s2)c(=O)[nH]1 +COC(=O)CN1CCCN(C(=O)Nc2cccc3ccccc23)CC1 +Cc1cc(C)n2nc(CC(=O)NC(C)c3ccc(C)c(F)c3)nc2n1 +COc1cc(Cl)c(C(O)c2cccs2)cc1OC +CCOC(=O)C(O)Cc1nc2cc(C(N)=O)ccc2n1C +COCC(C)n1c(C)cc(C(=O)CN(C)c2ccccc2)c1C +CC(C)(C)OC(=O)N1CCN(C2CCCCC2O)CC1 +Brc1ccn2nc(C3CCCCC3)ncc12 +NS(=O)(=O)c1ccc(OCCSc2nccn2C2CC2)cc1 +CC(C)(CO)C(CNC(=O)c1cnc(C2CC2)s1)c1ccccc1 +Cc1ccc(CN2CC(C(=O)Nc3ncccc3C)CC2=O)cc1 +CCC(C)n1ncc(C(=O)N(C)Cc2cccc(F)c2)c1C1CC1 +COc1ccc(CCNC(=O)CS(=O)(=O)c2nccn2C)cc1 +CCOCCOc1ccccc1NC(=O)N1CCC(F)(F)CC1 +COc1cccc(C(=O)c2ccc(NC(C)=O)cc2)c1 +CCOCCCNC(=O)c1cccc(NC(=O)N(C)C)c1 +CC(c1ccccn1)N(C(=O)COc1ccc(C#N)cc1)C1CC1 +CCC(NC(=O)c1csc(C)n1)c1ccc(S(C)(=O)=O)cc1 +O=C(Nc1cccc2cnccc12)c1ccc(-n2ccnc2)nc1 +O=c1[nH]c2ccc(S(=O)(=O)N(Cc3ccncc3)C3CC3)cc2[nH]1 +Cn1nnc2cc(C(=O)Nc3ccc(-c4ccno4)cc3)ccc21 +O=S(=O)(NCC1(O)CCc2ccccc21)c1ccc(F)cc1 +CC(=O)c1c(F)cccc1Sc1nccn1C +CN(C)C(=O)c1cccc(CN2CCN(c3ccccc3F)CC2)c1 +Cn1cc(NC(=O)Nc2ccc(Cl)cc2)ccc1=O +O=C(COC(=O)c1cc2ccccc2cc1O)NC1CC1 +Cc1ccc2nc(C(C(C)C)N3Cc4ncccc4C3=O)[nH]c2c1 +O=C1c2ccccc2NC(c2ccccc2Cl)N1C1CC1 +CCCn1cc(C(=O)Cn2cnc3ccccc3c2=O)c2ccccc21 +CCNC(=O)c1ccc(NC(=O)COc2ccccc2)c(C)c1 +Cc1cccc(C)c1OCCC(=O)N(C)CCO +COc1cccc(C(C)(O)c2ccccc2Cl)c1 +Cc1ccc(C(=O)Nc2cccc(C(=O)NCc3ccccc3)c2)o1 +NS(=O)(=O)c1cccc(NC(=O)NC2CCc3c(F)cccc32)c1 +CCC(C)CN(C)C(=O)c1c[nH]c2cccc(F)c12 +Cc1noc(C)c1Cc1ccc(C(=O)NCCCn2cccn2)o1 +O=C(Cn1nccc1-c1ccncc1)Nc1ccccc1OC(F)F +COc1ccccc1NCc1cccc(OC)c1OC +CC(C)CCN(C)C(=O)Cc1ccc(-n2cccn2)cc1 +CC1CN(CC(O)Cn2nc(-c3cccs3)oc2=O)CC(C)O1 +CC(=O)c1ccccc1NC(=O)Cc1cccc(Cl)c1 +O=C(c1cc2cc(F)ccc2[nH]1)N1CCCCC1Cn1cccn1 +Cc1ccc(N)c2ccnc(C(=O)N3CCCCC3)c12 +CCc1ccc(C(=O)N2CCN(c3nc(C)cc(OC)n3)CC2)o1 +CCc1cc(OC2CNC(C(=O)OC)C2)ccc1Cl +CCOC(=O)c1csc(-c2cnn(-c3ccccc3)c2)n1 +CCc1onc(C)c1NC(=O)Cc1cccc(Cl)c1 +CC(=O)Nc1nnc(SCC(=O)Nc2ccc(F)cc2)s1 +COc1ccc(C(=O)OCC(=O)NCC(C)C)c(F)c1 +CC(C)C(NC(=O)CC1CCCC1)c1nc(C2CC2)no1 +Cc1oc(C)c(C(=O)Nc2ccc(Cn3ccnc3C)cc2)c1C +O=C(Nc1ccccn1)c1ccc(-c2cscn2)cc1 +NC(=O)c1cnc2n1CCN(C(=O)c1ccccc1-n1cncn1)C2 +Cc1ccc2cccc(OC(=O)c3ccco3)c2n1 +Cc1cc(C)c(CNC(=O)c2ccccc2O)c(=O)[nH]1 +Cc1nc(NC(=O)NCC(=O)NCC(F)(F)F)oc1C +Brc1cccc(-c2noc(-c3ccnnc3)n2)c1 +CC1CCN(S(=O)(=O)NCCC(=O)N(C)C)CC1 +COc1ccc(C(C#N)Cc2ccncc2)c(OC)c1 +O=S1(=O)N=C(NC2CC2)Nc2ccc(Br)cc21 +Cc1ccc(C(=O)CCC(=O)NCc2ccc3c(c2)OCCO3)s1 +CCC(=O)N1CCCc2cc(NC(=O)c3ccccc3C)ccc21 +Cc1noc(C)c1C(C)CC(=O)N(C)c1cccc2ncccc12 +Cc1cc(C)c(S(=O)(=O)N2CCCCC2CCO)c(C)c1 +O=C(NCC1CCCO1)c1ccc2c(c1)CNCC2 +Cn1nc(CO)cc1-c1ccc(Cl)c(Cl)c1 +O=C(Cn1ncc(=O)c2ccccc21)N1CCCC1 +COC(=O)c1ccc(C(=O)NCC2(O)CCCC2)cc1 +COCCc1nc(N)cc(Nc2ccc(F)cc2)n1 +Cn1c(-c2ccccc2)cnc1S(=O)(=O)CC1CCCO1 +Cc1cc(C)n(Cc2cccc(C(=O)NCCN3CCOCC3)c2)n1 +COc1ccc(C(O)CNC(=O)CNc2cccc(Cl)c2)cc1 +CC(C)N1CC(C(=O)Nc2c[nH]ccc2=O)CC1=O +CC(CN1CCCC1=O)NC(=O)c1ccc(F)cc1 +Cc1ccsc1CNS(=O)(=O)c1c(F)cccc1F +Cc1cccc(NC(=O)c2c[nH]c3ccc(F)cc3c2=O)n1 +CC(C)Sc1ccccc1C(=O)Nc1ccccn1 +COc1cc(CNc2ccc(C)cc2)ccc1OCC(N)=O +Cn1cc(C(=O)N2CCCC(n3cccn3)C2)c(C2CCCCC2)n1 +Cc1cc(C(=O)N2CCCN(C(=O)OC(C)(C)C)CC2)no1 +Cc1ccc(F)cc1NC(=O)c1ccc(S(=O)(=O)NC2CC2)cc1 +Cc1nn(S(=O)(=O)N2CCOCC2)c(C)c1C +O=C(c1cc(-c2ccco2)on1)N1CCOC(c2ccccc2)C1 +CN(CCC(=O)Nc1sccc1C#N)c1ccccc1 +O=C(NCc1cc(-c2ccccc2)on1)c1cc(-c2ccco2)on1 +COC(=O)CNc1ncnc2c(-c3ccccc3)c[nH]c12 +CC(Sc1nccc(C(F)(F)F)n1)C(=O)NC(C)(C)C +CC(C)CN1C(=O)CCc2cc(NC(=O)C3CCC3)ccc21 +Nc1cc(F)ccc1-c1nc(-c2ccc3c(c2)OCO3)no1 +Cc1noc(C)c1Cn1nnc(CO)c1-c1ccc(Cl)cc1 +CCC(C)NC(=O)c1cccc(CNC(=O)NCc2ccco2)c1 +Cc1ncc(CNC(=O)Cc2ccc(-n3cnnn3)cc2)s1 +CC(C(=O)N1CCc2ccccc2C1)n1cc(Br)cn1 +Nn1c(SCc2ccc(F)cc2)nncc1=O +CC(Oc1ccc(F)c(F)c1)C(=O)N1CCCC1 +Cn1c(SCC(=O)Nc2nccs2)nnc1-c1ccc(N)cc1 +CC(NC(=O)N1CCCCCC1)c1ccc(S(C)(=O)=O)cc1 +Cc1ccc(Cn2cnc3sc(C)c(C)c3c2=O)cc1 +Cc1ccc(N2CC(C(=O)N3CCCC(C)C3)CC2=O)cc1C +CN(CCc1ccccn1)S(=O)(=O)c1ccc(C#N)cc1Cl +CCOC(=O)CN(CC)C(=O)c1cnc2onc(C)c2c1 +Cn1ncc2[nH]c(-c3c[nH]nc3-c3ccc(F)cc3)nc21 +CCCC(C)C(=O)N(C)c1nc(C)c(C(=O)OCC)s1 +CCOC(=O)CN(C)C(=O)c1ccc(N)cc1Cl +CCCCNC(=O)CCC(O)c1ccc(F)c(N)c1 +CC(C)CCc1nc(CN2CCN(C(=O)C(C)(C)C)CC2)cs1 +Cc1cc(NC(=O)c2ccc(Cn3ccnc3)cc2)sn1 +CCCCCN(C)C(=O)c1ccccc1S(N)(=O)=O +CCc1nnc2n1CCN(C(=O)Cc1csc(C(C)(C)C)n1)C2 +CCC1CN(C(=O)Cn2c(-c3ccccc3)noc2=O)CCO1 +CN(C)c1cccc(OCCN2CCCCS2(=O)=O)c1 +Cc1ccc(C(=O)Nc2ccc(Cl)cc2N)s1 +N#Cc1cccc(CN2C=NS(=O)(=O)c3ccccc32)c1 +CNC(=O)CCOc1ccc(NC(=O)Cc2ccc[nH]2)cc1 +Cc1nn(-c2ccc(F)cc2)c2sc(C(=O)OCC(N)=O)cc12 +CC(=O)N1CCOC(CNCc2cc(=O)c3cccc(Cl)c3[nH]2)C1 +Cn1cnc(CNS(=O)(=O)c2ccc(OC3CCCC3)cc2)n1 +COC(=O)COc1cc(-c2ccc(C)cc2)nc2ccc(N)cc12 +COc1ccc(CN2CCc3nncn3CC2)c(OC)c1OC +O=C1CC(C(=O)N2CCCS2(=O)=O)CN1CC(F)(F)F +O=S(=O)(NCc1ccccn1)c1cccc(F)c1 +CSc1cccc(NC(=O)Cn2c(C)nc3onc(C)c3c2=O)c1 +O=C(CCc1cscn1)Nc1cnc(-c2cccc(O)c2)nc1 +Cc1nnc(NC(=O)Cn2ccc(=O)n(C)c2=O)s1 +CCNS(=O)(=O)c1ccc(NCc2nncn2C)cc1 +COCCn1cc2c(n1)C(CNC(=O)c1ccncc1)OCC2 +CC(NC(=O)Cn1cnc2ccccc21)c1ccccn1 +COC(=O)c1cccc(C(=O)Nc2cccnc2)n1 +CS(=O)(=O)c1ccc(OCCNc2cccc(F)c2C#N)cc1 +CCN(C)c1ccc(C(=O)Nc2c[nH]ccc2=O)cc1 +N#CCc1nc2c(s1)CCOc1c(Cl)cccc1-2 +CC(=O)Nc1sc2c(c1C#N)CCN(Cc1ccccc1)C2 +CC(C)Nc1ncnc(Oc2ccc(Br)cc2)c1N +OCCC1CC2(CCCC2)Oc2ccc(F)cc21 +COc1cc(CCNc2cn[nH]c(=O)c2Cl)ccc1OC(F)F +Cn1ccnc(NC(=O)c2ccc(-c3ccccc3F)s2)c1=O +CC(=O)n1cc(C2CCCCC(=O)C2)c2ccccc21 +O=C1CCCN1c1ccc(CC(=O)N2CCCC2c2ccc[nH]2)cc1 +COC(=O)c1ccsc1NC(=O)c1ccc(F)cc1Cl +Cc1ccccc1Cn1c(=O)[nH]c2ccccc2c1=O +Cc1cc(C(=O)N2CCC3C2CCN3S(C)(=O)=O)c(C)o1 +Cn1cnc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 +CC(=O)NC1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +Cc1ccccc1C1C(=O)NCCN1Cc1cc(C(N)=O)cs1 +Cc1nnc(S(=O)(=O)Cc2cc(-c3ccco3)on2)n1C +Cc1ccc(C(=O)N2CCN(c3ccccc3F)CC2)c(=O)[nH]1 +CC(Oc1ccc(Cl)cc1)c1nc(-c2ccc(C#N)cn2)no1 +NC(=O)Cn1c(SCC2CCCO2)nnc1-c1cccs1 +CCOC(=O)c1cnc(SC)nc1-c1cccc2cccnc12 +CC(=O)OCCCNc1nc2c([nH]1)c(=O)n(C)c(=O)n2C +COc1ccc(Cl)cc1-c1cc(NC(=O)c2cc[nH]n2)[nH]n1 +Cc1ccc(C)c(NC(=O)c2nnn(-c3ccccc3)c2N)c1 +CC(Cc1ccco1)NS(=O)(=O)Cc1ccccc1 +CC(C)(C)C(=O)Nc1ccccc1NC(=O)c1ccco1 +CCOc1cccc2c1C(c1cc[nH]c(=O)c1)NCC2 +Cc1cc(C)n2nc(C(=O)Nc3nc(-c4ccco4)cs3)nc2n1 +CCCNC(=O)c1cccc(NC(=O)NCc2ccc(OC)cc2)c1 +CCCN(Cc1c(C)nn(C)c1C)C(=O)C(CC)CC +O=C(c1cccs1)N1CCCC(OCc2ccccc2F)C1 +CC(NC(=O)c1ccco1)C(=O)NC1CCc2ccccc21 +CCN(Cc1ccc2c(c1)OCCO2)C(=O)c1n[nH]c2ccccc12 +CC(C)NC(=O)CCCn1c(=O)c2cccn2c2ccccc21 +NS(=O)(=O)c1c(Cl)ccc2c1OC(F)(F)O2 +C#CCN1CCC(C(=O)NCc2ccsc2)CC1 +CCC1CN(C)c2ccccc2CN1C(=O)Nc1cc(C)on1 +COc1ccc(C(=O)NCC(=O)N(C)Cc2ccc(C)o2)cc1OC +Cc1ccc(C(=O)Nc2sc3c(c2C#N)CCCCC3)o1 +NS(=O)(=O)c1ccccc1NCCC1CCCCC1 +C#CCOc1cccc(NC(=O)c2ccc3[nH]c(=O)[nH]c3c2)c1 +CN(Cc1cnn(C)c1)C(=O)COc1cc(Cl)cc(Cl)c1 +c1coc(-c2nnc(CN3CCCCC3C3OCCO3)o2)c1 +O=C(NCc1ccco1)c1ccc(Cn2cnc3ccccc3c2=O)o1 +CC(C)C(NC(=O)Nc1cn[nH]c1)c1ccccc1 +COc1cccc(C(=O)N2CCN(c3cccc(C)c3)CC2)c1OC +O=C(CCOc1ccccc1)NCc1cccnc1-n1ccnc1 +OCc1cnc(-c2cccc(C(F)(F)F)c2)s1 +Cc1ncc(CNc2ccc3[nH]nc(C(N)=O)c3c2)n1-c1ccccc1 +Cc1cc(O)c(C2OC(=O)c3ccccc32)c(=O)o1 +CCCc1nc(CSc2ccc(Br)cn2)no1 +Cc1csc(-c2ccc(NC(=O)NCC(C)CC(C)O)cc2)n1 +COc1ccc(C(=O)c2ncc(-c3ccc(OC)cc3)[nH]2)cc1 +COc1ccc(NC(C)c2ccc(O)c(OC)c2)cn1 +COc1ccc(O)c(C(=O)NCC(C)(O)c2ccc(F)cc2)c1 +CC(=O)Nc1cccc(NC(=O)NCC(=O)Nc2ccc(F)cc2)c1 +Cn1nc(C2CN(C(=O)c3cnco3)C2)c2nccnc21 +O=C(Nc1ccc2c(c1)COC2)C1Cc2cc(F)ccc2O1 +Cc1ccc(C(=O)NCC#CCOc2ccccc2C(N)=O)cc1 +Cc1nc(CCN(C)C(=O)Nc2cc(F)c(F)cc2F)no1 +CC(C)N(C)C(=O)CNC(=O)c1ccc2c(c1)CCC2 +Cn1nccc1CNC(=O)CCNC(=O)c1ccco1 +COC(=O)c1ccc(NC(=O)C2COc3ccccc3O2)c(C)c1 +COCc1cccc(CNC(=O)Nc2cnn(CC3CCCO3)c2)c1 +CNc1cc(C(=O)N2CCC3(CCO3)CC2)ccn1 +O=C(CSc1ccccc1F)Oc1cccc(C(=O)NC2CC2)c1 +Cc1ccc(C)c(S(=O)(=O)Nc2nccc(C)n2)c1 +CCCN(CC1CC1)S(=O)(=O)N1CCCCCC1 +O=C(CCCn1cncn1)Nc1nnc(-c2ccccc2Cl)s1 +COc1cc(CNC(=O)c2cncc(Br)c2)ccc1C +CC1OCCN(Cc2cnc(C(C)(C)C)s2)C1C +Cc1ccc(C)c(NC(=O)NCCS(=O)(=O)c2ccccc2)c1 +NC(=O)CCN(Cc1ccccc1)C(=O)c1cc(-c2ccccc2)no1 +COc1ccnc(NC(=O)COc2ccc3ccc(=O)oc3c2)c1 +CC12CC(NC(=O)N1)c1cc(Cl)cc(Cl)c1O2 +Cc1cc(CS(=O)(=O)c2ccc(Br)cc2)on1 +O=C(CCC(=O)c1cccs1)Nc1cc(C(F)(F)F)ccc1O +Cn1c(-c2c(F)ccc(F)c2F)nc2cc(N)ccc21 +CCOCCCNC(=O)Cn1cnc2ccccc2c1=O +NC(=O)c1ccc(NC(=O)NC2CCCC2)cc1Cl +O=C(N1CCCC1)N1CCC2(CC1)CCN(CC1CC1)C2=O +CCc1noc(C(C)Nc2nc(C3CCCC3)nc3c2cnn3C)n1 +Cc1nc[nH]c1-c1n[nH]c(=O)n1-c1cccc2ccccc12 +CN1C(=O)CC(C(=O)NCCc2ccccc2)C1c1ccc(F)cc1 +Cc1cc(C)n2ncc(-c3noc(COCC4CCCO4)n3)c2n1 +CCN(CC(=O)NCC1COCCO1)c1ccccc1 +CCOC(=O)C1C2CCC(CC23CC3)N1C(=O)OC(C)(C)C +Cc1cc(CN2CCOC(c3nc(C)n[nH]3)C2)on1 +CCOC(=O)CN(C)c1c(C)c(C)nc2ncnn12 +CCCNC(=O)Cn1nc(-c2cccs2)c2sc(C)nc2c1=O +CC(C)CNC(=O)Cn1c(C2CC2)nc2ccccc21 +O=C(Cn1nc(-c2cc3c(s2)CCC3)oc1=O)NC1CCCCC1 +CCn1c(SCC(O)c2ccccc2F)nnc1-c1ccncc1 +Cc1cnc(C(=O)OCC(=O)Nc2cc(C)on2)cn1 +Cc1ccc(C2(CNC(=O)c3ccnn3C)CCOCC2)cc1 +CC(CC#N)N1CCN(c2ccc(Br)cn2)CC1 +COc1ccc(S(=O)(=O)NCc2cc(C)oc2C)c(OC)c1 +CC(C)(C)c1nnc(-c2ccc(NC(=O)c3ccco3)cc2)o1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(OC)cc2OC)c1C +COc1ccccc1NC(=O)N(C(C)C)C1CCN(C(C)=O)CC1 +CNC(=O)C1CCC(NC(=O)c2cc(C3CC3)n(C(C)(C)C)n2)CC1 +O=C(CSc1nccn1-c1ccccc1)c1ccccc1 +CC1(C(=O)NCc2ccccc2)CCC(=O)N1c1ccc(F)cc1 +CCC(C)n1ncc(C(=O)N(C)Cc2ccc(C)s2)c1C1CC1 +CC(C)(C)c1cnc(COC(=O)C2CCCN(S(C)(=O)=O)C2)o1 +O=C(CNC(=O)c1cccs1)NCc1ccc(F)cc1 +c1ccc2c(c1)CCN2CCCNc1ncnc2sccc12 +Cc1nc2cc(NC(=O)N3CCN(c4ccccc4)CC3)ccc2n1C +CCCC(=O)NCc1nn(C)c(=O)c2ccccc12 +O=C(COC(=O)C1CCC1)Nc1ccc2c(c1)OCO2 +O=C(Nc1cccc(CO)c1)c1ccc2c(c1)OCCO2 +Nn1c(SCC2CCCC2)nnc1-c1ccco1 +COc1cccc(-c2nc(C)nc3ccccc23)c1OC +COC(=O)C(C)(C)c1ccc(NC(=O)Cc2ccc[nH]2)cc1 +O=c1ccc(CNS(=O)(=O)CCc2ccccc2)c[nH]1 +COC(=O)CC(c1ccc(Br)cc1)C1CC1 +CC1CN(C(=O)c2cncn2-c2ccccc2)CC(C)(C)O1 +Cn1c(SCc2ncc(-c3ccc(F)cc3)o2)n[nH]c1=O +CCc1cccc(C)c1NC(=O)CCn1c(C)csc1=O +Cc1[nH]nc(-c2ccc(O)cc2O)c1-c1cnn(-c2ccccc2)c1 +CCn1nc(-c2ccccn2)nc1CC(F)(F)F +CCOC(=O)Nc1ccc2c(C(C)C)cc(=O)[nH]c2c1 +CCC(CN1CCOCC1)NC(=O)Cc1ccc2c(c1)OCCCO2 +Cc1nn(C)c2sc(C(=O)OCCOc3ccc(C#N)cc3)cc12 +O=C(NC1CCC(O)CC1)N1CCCC1c1cccs1 +COc1ccc(CCNC(=O)c2c(C)noc2C)cc1OC +O=C(C1CC1)N1CC2OCC(=O)N(Cc3ccc(F)cc3)C2C1 +CN(Cc1ccc(-n2cncn2)cc1)CC(F)F +Cc1ccc(COc2cccc(CNc3nnnn3C)c2)cc1 +CN(CC(O)C1CC1)C(=O)NCC(C)(C)c1ccncc1 +COc1ccnc(N2CCN(CC(O)c3ccccc3)C(C)C2)n1 +CCCNc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1Cl +O=C(NC1CCCC1)c1csc(-c2cnccn2)n1 +CCc1ncc(NC(=O)N2CCC(Oc3cccc(Cl)c3)C2)cn1 +O=C(Nc1ccccc1C1CC1)c1nn2cccnc2c1Cl +CS(=O)(=O)c1ccc(C(=O)NCCN2CCCCCC2=O)cc1 +COc1ccc(F)cc1NC(=O)Cc1cc(C)[nH]n1 +CCc1nc(CNc2ccc(S(=O)(=O)NC(C)C)cc2)no1 +CC(C)C(=O)NCc1csc(C2CCCN(C(=O)C3CC3)C2)n1 +CCc1onc(C)c1NC(=O)N1CCCC1c1cccc(C)n1 +CNC(=O)c1ccc(NC(=O)NCc2ncc[nH]2)cc1Cl +O=C(CCn1ccccc1=O)Nc1n[nH]c(-c2cccc(Cl)c2)n1 +Cc1cc(S(=O)(=O)N2CCCCC2c2nncn2C)ccc1F +CCCC(=O)N1CCN(c2ccc(-c3ccccc3OC)nn2)CC1 +CCC(C)C(NC(=O)CSc1ccncc1)C(N)=O +NS(=O)(=O)N1CCN(C(=O)c2ccccc2F)CC1 +COc1cc(C(O)COc2ccc(C)cc2N)c(OC)cc1Cl +Cc1c(O)ccc2c(CN3CCc4ccccc4C3)cc(=O)oc12 +COCCn1c(C2CC(=O)N(Cc3ccco3)C2)nc2ccccc21 +O=C(Nc1cc(Cl)ccc1O)C1CCN(C(=O)c2ccoc2)CC1 +Cc1noc(-c2ccc(S(=O)(=O)NC3CCCC3)s2)c1C +O=C(NCc1cccnc1Oc1ccccc1F)c1ccsc1 +CCCc1nc(COc2ccc3c(c2)CCCC3=O)no1 +CN(C(=O)C1CCN(c2ccc3cccc(O)c3n2)CC1)C1CC1 +O=C(NCc1cscn1)NCc1ccccc1F +CC1CCC(n2c(=O)[nH]c3ccccc3c2=O)CC1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1ncc(C(C)C)s1 +O=C1NCCCCC1Sc1nc2ccccc2s1 +COCC(O)CN(C)c1cc(C)cc2ncnn12 +O=C(NCCCn1ccnn1)c1ccc(-c2ccccc2Cl)o1 +CNC(=O)C(C)Nc1nc2cc(Cl)ccc2s1 +Cc1ccc(-c2cc(-c3c(C)nn(CCO)c3C)c(C#N)c(N)n2)cc1 +CC(=O)N(CCC(=O)NC(C)c1c(C)noc1C)Cc1ccccc1 +c1cncc(COC2CC3CN(Cc4cccs4)CCN3C2)c1 +COc1cccc(Cn2c(=O)[nH]c3ccccc3c2=O)c1 +CCC1CNc2cc(S(=O)(=O)N3CCCCC3C)ccc2O1 +CC1(C)CC(NC(=O)Cn2ncc3ccccc3c2=O)CCO1 +O=C(C1CCCC1)N1CCC(c2nnc(-c3ccsc3)o2)CC1 +CN(CC1CCCCC1)C(=O)c1cc2ccccc2[nH]c1=O +CCC(NC(=O)c1csnn1)C1CN(Cc2ccccc2)CCO1 +CC(=O)NCCNC(=O)Nc1ccc(OCc2ccccc2)cc1 +CCC1CCCCN1C(=O)CNc1ccc(N2CCCC2=O)cc1 +O=C1CC2CCCC(C1)N2c1ccc(F)cc1F +CNC(=O)NCc1ccc(OC)c(OC)c1OC +COc1ccc(C)cc1N1CCN(C(=O)NC(C)C)C(C)C1=O +CC(CCc1ccccc1)NS(=O)(=O)c1ccc2c(c1)OCCO2 +CC(C)Oc1ccc(-c2nnc3ccccn23)cc1N +CC(C(=O)N1CCCC1)N1CCN(C(=O)C2CC2c2ccco2)CC1 +C=CCOCCCC(=O)N1CC(C)OCC1(C)C +Cc1ccc2c(Nc3cccc(O)c3)c(C(=O)OC(C)C)cnc2n1 +CC1COCCN1CC(=O)Nc1cccc(C(=O)NC2CC2)c1 +CN(CC(=O)NC(C)(C)C)S(=O)(=O)c1cccnc1 +O=C(NCc1csc(=O)[nH]1)c1cn(Cc2cccc(F)c2)nn1 +Cc1cccc(C(=O)NCc2ccc3c(c2)OCCO3)c1 +Nc1cc(Cl)ccc1C(=O)OCC(=O)NC1CC1 +CC(C)c1cccc(OCC(=O)N2CCNC(=O)CC2)c1 +Cc1noc(C(C)C)c1C(=O)OC(C)C(=O)c1c[nH]c2ccccc12 +CCS(=O)(=O)N(CCO)c1cc(C)cc(C)c1 +CN(Cc1ccc(O)cc1)C(=O)CCC(=O)c1ccc2c(c1)CCC2 +CCC1CCCN(C(=O)c2cc(Cl)c3c(c2)OCCO3)C1 +CC(c1nc(-c2cccnn2)no1)n1cnc2ccccc2c1=O +O=C(NCc1ccccn1)c1cc(-c2ccccc2Cl)[nH]n1 +C=CCCC1NCCc2cc(F)cc(Br)c21 +COc1ccc2c(c1)NC(=O)C=C(c1ccc(Cl)cc1)N2 +O=C(CSc1nnnn1Cc1ccccc1)c1ccc(O)cc1O +Cc1ccc(-c2c(C)sc3nc(C)nc(NCCCO)c23)cc1 +Clc1cccc(Oc2cc(N3CCOCC3)ncn2)c1 +Cc1c(C(=O)NCC(C)C)cnn1-c1ccncc1 +CCc1ccccc1CNC(=O)NC1CCCC(C(=O)NC(C)C)C1 +COCc1ccccc1NC(=O)c1cccnc1OCC(F)F +NC(=O)c1ccc(CN(C(=O)Nc2nncs2)C2CC2)cc1 +c1ccc2sc(N3CCn4c(nnc4C4CC4)C3)nc2c1 +CC1CN(C(=O)NC(C)c2ccccc2Br)CCO1 +CC1CCC(N(C)C(=O)c2ccc3c(c2)CCO3)CC1 +CCC(C)NC(=O)NCC(C)Oc1ccccc1 +CCC(=O)Nc1cccc(NC(=O)CC2CCOc3ccccc32)c1 +Cc1cc(C(=O)N2CCN(Cc3ccc4c(c3)CCO4)CC2)no1 +CCc1onc(C)c1NC(=O)Cc1c(C)nn(CC(C)C)c1C +CN(C(=O)c1ccc(S(C)(=O)=O)cc1)C1(C#N)CCC1 +C=CCOCC12CCCOC1CCN(C(=O)c1cccn1C)C2 +CC(C)(CO)NC(=O)C1CCCN1S(C)(=O)=O +CCCc1cc(C(=O)N2CCN(c3nc(C)cc(OC)n3)CC2)[nH]n1 +Cc1cccc(CNC(=O)NCc2cc(=O)[nH]c3ccccc23)c1 +CC1CCCN(c2ncnc3c2oc2ccccc23)C1 +Cc1ccc(S(C)(=O)=O)cc1NC(=O)CCc1ccsc1 +COC(=O)N(C)c1ccc(NC(=O)Nc2ccc(C#N)cc2)cc1 +CCCCNC(=O)CNC(=O)c1cc(C)n(C)n1 +CN1CN(C)C(N)=C(C2OC(=O)c3ccccc32)C1=O +O=C(NCCc1cccs1)N1CCC(Oc2cccnc2)C1 +Cc1cccc(C(=O)N2CCOC(c3cccc(OC(F)F)c3)C2)n1 +O=C(Nc1ccccc1-n1cccn1)N1CCc2ccc(O)cc2C1 +O=C(CSc1nnc(-c2ccncc2)o1)Nc1ccccc1F +Cc1ccc(=NS(=O)(=O)c2ccc(N)cc2Br)[nH]c1 +N#Cc1cccc(C(=O)N(CC(F)(F)F)c2ccccn2)c1 +CCCn1c2ccccc2c2nnc(SCC(=O)NC3CC3)nc21 +N#CCc1ccccc1C(=O)NCCc1ccccc1 +CC(=O)c1ccc(NCC(=O)N2CC(C)OC(C)C2)cc1 +Cc1cc(C(F)(F)F)n(CC(C)CNC(=O)C2CCOCC2)n1 +COCCN1C(=O)CCC2C1CCN2C(=O)Cc1ccc(C)cc1 +CCCCc1nnc(NC(=O)Cc2ccc(C)nc2)s1 +CCOc1ccc(-c2nnc(SC(C)C)n2N)cc1 +COc1ccc(NC(=O)N2CCCC2CO)cc1OC +O=C(Nc1ccc(-n2cccn2)nc1)C1CCCCC1 +CC(C)CNc1nnc(-c2cnc(C(C)C)s2)s1 +CC1CN(CC=Cc2ccccc2)CC(C(N)=O)O1 +Cc1cc2[nH]c(=O)[nH]c2cc1NC(=O)NCCC(C)C +CCc1ncc(C(=O)N(C)Cc2ccc(OC)c3ncccc23)cn1 +Cc1ccc(OCc2c(CO)nnn2-c2cccc(F)c2)cc1 +CNC(=O)C1CCC(NC(=O)CCCNC(C)=O)CC1 +CCc1cc(Sc2ccccc2OC)n2ncnc2n1 +Cc1nc(CNC(=O)C(NC(=O)CC(C)C)C(C)C)c(C)s1 +CS(=O)(=O)NCC1CCCN(C(=O)c2cccc3ccccc23)C1 +O=C(NCc1ccccc1)c1c[nH]c2cc(C(F)(F)F)ccc2c1=O +NC(=O)COc1ccc(NC(=O)N2CCc3sccc3C2)cc1 +CC(NC1=NS(=O)(=O)c2ccccc2N1)c1ccccc1 +N#CCc1ccc(CCC(=O)OCc2ccccc2)cn1 +Cc1ccc(NC(=O)CCc2ccccc2)cc1S(C)(=O)=O +O=C(NCc1ccc(F)c(Cl)c1)NCc1ccc2c(c1)OCO2 +CCOCCSc1ccnc2c1c(=O)n(C)c(=O)n2C +Nc1nc(NCc2ccccc2)nc(-c2cc[nH]n2)n1 +CC(C)(O)CCc1ccc(C(=O)N2CCCC2CCO)cc1 +COCCC1(C(=O)Nc2cc(OC)ccn2)CC1 +Clc1ccc(OCc2nc(-c3ccncc3)no2)c2ncccc12 +O=C1CCc2cc(C(=O)NCC3CCN(c4ccccc4)C3)ccc2N1 +CC(C)(C)C(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +OC(CCN1CCOCC1)c1ccc2ccccc2c1 +CSc1cccc(NC(=O)NCC(=O)OC(C)C)c1 +O=C(NCc1ccc2c(c1)OCO2)Nc1ccccc1F +COc1ccccc1-c1ccc(C2NC(=O)CN2C)cc1 +CC(=O)c1ccccc1NC(=O)COC(=O)c1cccc(Cl)c1 +O=C(CCNC1=NS(=O)(=O)c2ccccc21)NCc1cccnc1 +Cc1cc(NC(=O)c2sccc2C)n(-c2ccc(F)cc2)n1 +CC(NC(=O)c1cnc(-c2ccccc2)s1)c1ncon1 +O=C(Cc1ccccc1F)Nc1cc(N2CCOCC2)ncn1 +CCOc1ccc(CNC(=O)c2c(C)nc(C(C)C)[nH]c2=O)cc1C +CC(=O)Nc1ccccc1OCC(=O)c1cc(C)n(C)c1C +CC(C)CC1(CNC(=O)Nc2cnn(-c3ncccn3)c2)CCCC1 +CCC(O)CN1CCN(C(=O)Cn2cc(C)cn2)CC1 +Cc1cc(NC(=O)c2ccc3c(c2)CCCC3)ccc1S(N)(=O)=O +COc1ccc(C2(C)Nc3ccccc3C(=O)N2C)cc1 +C#CCN(CC#CC)C(=O)Cn1cccc(C(F)(F)F)c1=O +NC(=O)COC(=O)C1CC(=O)N(Cc2ccccc2)C1 +COc1ccc(NC(=O)c2ccc(=O)n(C)c2)c2cccnc12 +COc1ccc(SC(C)C(=O)Nc2cccc(C)n2)cc1 +CC(=O)c1ccc(CNC(=O)c2cnc(N)c(Cl)c2)nc1C +O=C(NCC(c1ccccc1Cl)N1CCOCC1)Nc1cn[nH]c1 +Cc1cc(C)n2cc(CNc3ccccc3)nc2n1 +Cc1cccc(NC(=O)c2cccc3[nH]ccc23)n1 +O=C(NCC(O)c1cccc(C(F)(F)F)c1)NC1CCCC1 +COc1ccc(C(O)CN2CCN(c3ncccn3)CC2)cc1 +O=C(Nc1ccc2oc(-c3ccccc3Cl)nc2c1)c1nc[nH]n1 +CCC(NC(=O)CCC(=O)c1cccs1)c1cccs1 +CCc1nnc(NC(=O)CCNC(=O)c2ccnn2C)s1 +O=C(NCCc1cn2ccccc2n1)c1cccc(NC(=O)C2CC2)c1 +O=C(Nc1ccncc1F)c1ccc(Br)cn1 +Cc1nccc(CNC(=O)c2c(F)cccc2F)n1 +CC(=O)Nc1ccc(OC(C)C(=O)Nc2cccc(C(C)=O)c2)cc1 +COc1ccc(-c2noc(-c3cccc(OC(C)=O)c3)n2)cc1OC +Cc1ccc(C(=O)Nc2cc(F)c(F)cc2N)cc1 +CCOC(=O)c1cncc(C(=O)NC(C)c2ccccc2)c1 +COc1cccc(OC)c1C(=O)N1CCN(Cc2ccncc2)CC1 +N#Cc1ccc(CNC(=O)NCc2cnn(Cc3ccccc3)c2)cc1 +COc1ccc(F)cc1NC(=O)CCCNC(=O)C(C)(C)C +Cc1cccc(OC(F)F)c1NCC(=O)NC1CC1 +OCCCNc1cc(-c2ccc(F)cc2)nc(-c2cccnc2)n1 +C=CCOCC1CCC2C1OCCN2C(=O)c1ccc2[nH]ccc2c1 +COc1ccccc1NS(=O)(=O)c1ccc(Cl)cc1F +Cc1nc2nc(N)nn2c(C)c1CC(=O)Nc1ccc(F)cc1 +O=C(Nc1cccc(C(F)(F)F)c1)c1ncco1 +COc1ccc(C(=O)CSc2nnnn2-c2ccccc2C)cc1 +Cc1ccc(NC(=O)Cn2nnc3ccccc3c2=O)cc1 +Cc1nc(CN(C)C(=O)c2cc(Cl)ccc2F)no1 +CC(NC(C)c1ccc(Cl)cc1)C(=O)Nc1ncccn1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccc(F)cc1 +O=C(NCc1nc2ccccc2[nH]1)NCC1CCC1 +O=C(NC(CC(F)(F)F)c1ccc(F)cc1)c1ccccc1 +CN(CC(=O)Nc1cc(C#N)ccc1Cl)C(=O)c1cccs1 +COc1cc2c(c(Cl)c1OC)CCNC2C(C)C +CCc1noc(CNc2ccc(Cl)cc2C(=O)NC)n1 +N#CCn1ccc(NC(=O)c2cnc3sccn3c2=O)n1 +Cc1ccc(N2CCC(C(=O)NCc3ccc(F)cc3)C2=O)cc1F +CCC1CN(C(=O)Nc2ccc(Cl)cc2)CCO1 +Cc1cc(N(C)Cc2noc(C)n2)n2nc(C)c(C)c2n1 +CC(C)n1ncc2c1N=C(O)CC21C(=O)N(C)c2ccc(Cl)cc21 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1cc2ccccc2[nH]1 +COCCn1c(SCCO)nc2c([nH]c3ccccc32)c1=O +O=C(CNC(=O)c1cnc2cc[nH]c2c1)Nc1ccccc1 +CCC(CC)(CO)NS(=O)(=O)c1c(F)cccc1F +O=C(CCn1cncn1)NCC1(c2cccc(Cl)c2)CCCC1 +CN(C)C(=O)Cn1cc(C(=O)N2CCCC2c2ccccc2)nn1 +Cc1n[nH]c(C)c1CCC(=O)Nc1cccc2c1ccn2C +Cc1cccc(NC(=O)CCn2cc(Cl)cn2)c1C +Cc1nc2ccccc2nc1NCCC1CCCO1 +CCc1cccc(Oc2ccc(NC(=O)N3CCCC(O)C3)cn2)c1 +Cn1cc(C(=O)OCC(=O)Nc2ccccc2)c(C(C)(C)C)n1 +CC(C)OC(=O)c1c(NC(=O)C2CC2)sc2c1CCCC2 +CCC(O)c1c(-c2ccc(OC)c(OC)c2)nc2ccccn12 +CCCc1nc(COc2ccc(F)cc2)sc1CO +Cc1ccc(NC(=O)c2c[nH]c3ccccc23)c(O)c1 +O=C(NCc1ccc(CO)c(F)c1)Nc1ccc(F)cc1 +N#Cc1ccccc1S(=O)(=O)Nc1cccc(Cl)c1F +Cc1ccc(S(=O)(=O)N2CCOC(C)(C)C2)cc1 +O=C1C(=O)N(CC2CCCO2)c2c(Br)cc(F)cc21 +CCOC(=O)c1cc(C#N)c(SCC(=O)NC(C)C)nc1C +COCCCNC(=O)c1cccc(-n2cnc3cccnc32)c1 +CN(C)C(c1ccccc1)c1nnnn1-c1ccc(Cl)cc1 +Cc1noc(C)c1CN(C)C(=O)C1Cc2ccccc2CN1 +COc1ccc(F)cc1S(=O)(=O)Nc1ccc(F)cc1 +CCCOC(=O)C(CC)N1C(=O)C(C)Oc2ccc(C(C)=O)cc21 +O=C(Nc1cnn(-c2ccccc2F)c1)c1n[nH]c(=O)c2ccccc12 +CCOC(=O)CC1NCCc2cc(C)c(OC)cc21 +Cc1cc(N)c2oc(C(=O)Nc3ccccc3C)cc(=O)c2c1 +CC1CCCC(N(C)C(=O)CNC(=O)c2ccc3c(c2)OCO3)C1 +O=C(COCC1CC1)N1CCC(CC(=O)N2CCCC2)CC1 +O=C(Nc1cncc(Br)c1)OCc1ccccc1 +CC(=O)Nc1ccc2c(c1)nc(CN(C)C(=O)NC(C)C)n2C +COC(=O)c1c(C)[nH]c(C(=O)NCCc2nc3ccccc3[nH]2)c1C +CCOc1ncccc1CNC(=O)C1COc2ccccc2O1 +COc1ccc(NC(=O)COc2cccc(C(C)=O)c2)c(OC)c1 +CC(C)C(NC(N)=O)C(=O)NCc1ccc(-n2cccn2)cc1 +O=C(COc1cccc(C(F)(F)F)c1)Nc1nnc(C2CC2)s1 +Cc1ccccc1CN(c1cccc(F)c1)S(C)(=O)=O +O=C(CCc1c[nH]c2ccccc12)NCCc1[nH]nc2c1CCCC2 +COc1cc(CNC(=O)c2ccc(O)c(Cl)c2)ccn1 +CSc1ccc(CN(C)S(=O)(=O)c2ccc(F)c(F)c2)cc1 +COc1ccnc(NC(=O)c2ccccc2OC)c1 +CC(=O)NCC1OC(CO)C(O)C1N1CCN(c2ccccc2)CC1 +CCC(C)c1ccccc1OCC(=O)N1CCN(CCC#N)CC1 +COc1cccc(C(=O)Nc2cc(F)cc(F)c2)c1O +COc1ccc(C(=O)OCCc2scnc2C)cc1 +O=C(COC(=O)c1ccc2nccnc2c1)C1=NC=CC1 +CCOC(=O)N1CCC(NC(=O)c2cccnc2N2CCCC2)CC1 +CCc1ccccc1NC(=O)N1CCN(C(=O)C(C)(C)C)CC1 +CCC(C)NC(=O)CN1CC(CC)Oc2ccc(N)cc21 +O=C(c1cc(-c2cccnc2)nc2ccccc12)N1CCC1 +OCc1ccc(-c2ncccc2C(F)(F)F)cc1 +COc1cc2c(cc1OC)CCN(C(=O)Cc1csc(C)n1)CC2 +CC(Cc1cccs1)NC(=O)Nc1ccccn1 +CC(C)CCNC(=O)Cc1csc(NC(=O)C(C)(C)C)n1 +CCNc1ncc(C(=O)NCCOC)cc1Cl +COc1ccc(OCc2cccc(C#N)c2)c(N)c1 +CSc1cc(NC(=O)NCCc2ccccn2)ccn1 +Cc1nnc(C(C)Nc2ccc(-c3cccc(F)c3)c(F)c2)o1 +COc1ccc(-c2nc3c4ccccc4n(CCC#N)c(=O)n3n2)cc1 +CCCCSc1nnc(SC(C)C(=O)N(C)C)s1 +Cn1cnc2cc(C(=O)N3CCc4cc(F)ccc4C3)ccc21 +CC1CN(S(=O)(=O)c2ccc(N)cc2)CCO1 +CCCCn1c(C)cn2c3c(=O)n(CCOC)c(=O)n(C)c3nc12 +CCCOC(=O)CCc1cnn(-c2ccccc2)c1 +O=C(CSc1ncccn1)c1ccc2c(c1)OCCO2 +COC(=O)c1ccc(CNc2nncc(-c3ccc(F)cc3)n2)cc1 +CCC(C(=O)NCCc1nnc2ccccn12)c1ccccc1 +COC(=O)CNC(=O)c1cccnc1N1CCOCC1 +COc1ccc(CN(C(C)=O)c2cccc(N)c2)cc1OC +COC(=O)c1ccccc1NC(=O)COC(=O)c1ccoc1 +CNC(=O)Cn1cc(NC(C)c2ccc(C)o2)cn1 +O=C(COc1ccc(F)cc1)Nc1ccn(-c2ncccc2Cl)n1 +Cc1ccc(N)c(C)c1NC(=O)c1cc(Cl)ccc1O +O=C(CCn1[nH]c(=O)ccc1=O)Nc1cccc(Cl)c1 +COc1ccccc1OCCN1CCCS1(=O)=O +Cc1cccn2cc(-c3ccc(NC(=O)Cn4ccnn4)cc3)nc12 +Nc1cc2c(cc1Oc1ccccc1F)OCCO2 +CC(C)OCc1cccc(CNS(C)(=O)=O)c1 +O=C(NCc1ccccc1Cn1cccn1)c1ccc(F)cc1 +CCCNC(=O)CNC(=O)C1CC(=O)N(CC(F)(F)F)C1 +O=C1N=CC(CCC(=O)OCC(=O)Nc2cccc(Cl)c2)=N1 +CCc1nnc(NC(=O)C(NC(=O)c2ccco2)C(C)C)s1 +COc1ccc(CCC(=O)Nc2cccc(NC(C)=O)c2)cc1 +C#CCN1CCN(C(=O)NCCc2cccc(O)c2)CC1 +COc1cc(-c2n[nH]c(=O)n2-c2ccccc2Cl)ccc1O +CCNC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +Cc1noc(C)c1S(=O)(=O)NC(C)C(=O)N(C)C +Cc1nn(-c2ccccc2)nc1C(=O)OCC(=O)NC(C)(C)C +Cc1ccc(S(=O)(=O)NCc2ncoc2C)cc1C +CCOC(=O)c1nc(-c2ccccc2)sc1C(C)=O +CC(c1ccc(F)c(Cl)c1)n1cnc2c1c(=O)n(C)c(=O)n2C +COC(=O)c1cc2c([nH]c1=O)CC(c1ccc(C)s1)CC2=O +O=C(Nc1ccc(-n2cncn2)cc1)c1scnc1C1CC1 +Cc1nc2c(N)cccc2n1C(C)C(=O)OC1CCCCC1 +COc1ccc(C(CC#N)C(C#N)c2ccccc2)cc1OC +Cn1c(-c2ccc(C(=O)Nc3ccncc3)s2)nc2ccccc21 +Cc1nc(C(=O)Nc2nc3cc(Cl)ccc3n2C)cs1 +COC(=O)C1(N(C)C(=O)c2ccccn2)CCCCC1 +CC1(C)Cc2cc(CNC(C)(C)C(N)=O)ccc2O1 +O=C1Cc2cc(-c3csc(N4CCOCC4)n3)ccc2N1 +CN(c1cc2c(cc1N)CCC(=O)N2)C1CCCC1 +CC(C)Oc1ccc(CCNC(=O)Cc2ccc[nH]2)cc1 +O=C(NCCc1ccc(F)cc1F)c1nc2ccccc2c(=O)[nH]1 +CC(C)CN(C)C(=O)c1cc(Cl)ccc1-n1cnnn1 +COCc1nn(C(C)C)c2c1CCN(Cc1ccccn1)C2 +Cc1cc(C(F)(F)F)nn1CCCNC(=O)c1cccc(C#N)c1 +O=C(Cc1ccc(-n2cnnn2)cc1)OCc1ccc(F)cc1 +COc1cccc(C(=O)N(C)Cc2ccccc2)c1OC(F)F +NC(=O)C(Cc1ccccc1)NC(=O)c1cccc2ccccc12 +O=C(NCC1COc2ccccc2C1)c1cc(-c2ccncc2)n[nH]1 +COCCNC(=O)c1nc(-c2ccc(OC(C)C)cc2)no1 +COc1cc(CCNC(=O)Nc2cnccc2C)ccc1C +COc1ccc(S(=O)(=O)c2cnc(N)nc2)c(C)c1 +CSc1cc(C(=O)OCc2cccnc2)ccn1 +Cc1c(C(=O)N(C(C)C)C2CCC2)cnn1-c1ccccn1 +Cc1nnsc1C(=O)NCCn1ccc(-c2cccs2)n1 +O=S(=O)(c1cnc2ccsc2c1)N1CCCC1c1ccncc1 +O=C(NC1CCCc2occc21)c1sccc1Br +CN(CC(F)(F)F)C(=O)CC1OC(=O)c2ccccc21 +COc1ncc(-c2cc(C3(C)CC3)nc(N)c2C#N)cn1 +COc1cc(N)ccc1-c1nnc(N2CCCCC2)o1 +CC(Sc1ccccn1)C(=O)NCC1CCCO1 +NC(=O)c1ccc(COC(=O)c2ccc3ccccc3n2)cc1 +Cc1cccnc1NC(=O)CSc1ccccc1F +CS(=O)(=O)N1CCC(C(=O)c2cccs2)CC1 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+Cc1ccc(CC2(c3cccc(Br)c3)NC(N)=NC2=O)o1 +O=C1CCCN1c1ccc(NCc2ccc3c(c2)OCCO3)cc1 +COc1ccccc1C(=O)N1CCC(C(=O)c2ccnn2C)CC1 +Cc1nn(CCC(=O)NCCCO)c2ccccc12 +O=C(NC1CCCC1)c1cn(Cc2ccccc2)nc1-c1cccnc1 +Cc1ccc(NC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)nc1 +COc1ccc(OC)c(CCNC(=O)C2CC(=O)N(C)C2)c1 +O=C(COc1ccccc1)NCCc1csc(-c2ccncc2)n1 +CCc1ccc(NC(=O)C2CC2)cc1S(N)(=O)=O +Cc1occc1C(=O)Nc1ccnn1Cc1ccc(Cl)cc1 +CC(C)NC(=O)C1CCCN(S(=O)(=O)c2ccc(F)cc2)C1 +CCOc1ccccc1OCC(=O)NCC(N)=O +Cc1cc(CNC(=O)c2ccc(CNS(C)(=O)=O)o2)c(C)o1 +Cn1cccc1C1COCCN1CCCn1ccnc1 +CNC(=O)C(C)CN(C)C(=O)Nc1ccccc1-n1nc(C)nc1C +COc1ccc(Cl)cc1-c1nnc2sc(C)nn12 +COc1ccc(Cl)cc1NC(=O)c1nc2nc(C)cc(C)n2n1 +CCC(=O)N(Cc1cc2cccc(C)c2n2nnnc12)C1CCCC1 +Cc1cccc(S(=O)(=O)Nc2cccc(CS(N)(=O)=O)c2)c1 +O=C1NCCCN1CC(=O)N(Cc1ccsc1)C1CC1 +Cc1cccc(Oc2ncccc2NC(=O)NCc2ncc[nH]2)c1C +C=CCn1c(=O)n(-n2cnnc2)c(=O)c2c3c(sc21)CCCC3 +Cc1nnc(SCCCc2ccccc2)s1 +COc1cccc(CNC(=O)N2CCCCCC2c2ccco2)n1 +Cc1ccc(C(=O)Nc2nnc(-c3ccncc3)s2)cc1 +O=C(C1CCCO1)N1CCN(CCCOc2ccc(F)cc2)CC1 +CC(CNC(=O)CN1C(=O)CSc2ccccc21)N1CCOCC1 +Cn1ncc2c(=O)n(CC(=O)Nc3ccc(Cl)cc3F)cnc21 +CCOC(=O)c1cnn2c(C(F)F)cc(-c3cnn(CC)c3)nc12 +Cc1ccn2c(=O)c(NC(=O)c3ccc(C)c(C)c3)c(C)nc2c1 +CCC(Nc1cnn(CC(=O)NC2CC2)c1)C(C)C +CC(C)CC(NS(=O)(=O)c1cn[nH]c1)c1ccccc1 +O=C(COc1ccc(Cl)cc1Cl)NCCN1CCOCC1 +CCOCC(=O)NCc1n[nH]c(=O)c2ccccc12 +CCC1CCCCN1C(=O)NCc1cccc(CN2CCOCC2)c1 +COC(=O)N(C)c1ccc(NC(=O)CCC(=O)c2cccs2)cc1 +O=C(CNC(=O)c1ccc(Br)cc1)NCc1ccccc1 +COc1ccc(C(C#N)CN2CCOCC2)cc1F +CCCC(=O)N1CCC(C2CC(C(F)(F)F)n3ncnc3N2)CC1 +CC(=O)NC(C(=O)NC(C)c1ccc(C)cc1)C(C)C +CCN1CC(C(=O)OCC(=O)N2c3ccccc3CC2C)CC1=O +Cc1cc(CN(C)C(=O)c2cnn3c(-c4ccccc4)ccnc23)no1 +CC1COCCN1CCCn1cc(N)ccc1=O +Cc1ccc(N2CCOCC2)cc1Br +CC(=O)c1ccccc1NCC(=O)Nc1ccccc1Cl +Cc1cc(N)ccc1NS(=O)(=O)c1c(C)noc1C +CC(NC(=O)N1CCOCC1)c1cccc(Br)c1 +O=C(c1ccc(OCC(F)F)nc1)N1CCC(c2ccccc2)CC1 +Cc1ccc(Oc2ncccc2CNc2nc(C)cc(C)c2C#N)cn1 +CCSc1cc(C(=O)Nc2cc(C(=O)OC)ccc2F)ccn1 +CCC(=O)Nc1ccc(NC(=O)OC(C)(C)C)nc1 +OCc1c(OC2CCc3ccccc32)nc2sccn12 +COc1ccc(C)cc1CCNC(=O)COc1ccccc1C#N +Cc1ccc(NC(=O)c2nnn(Cc3ccc(F)cc3)c2N)cc1C +Fc1ccc(F)c(CNc2cnn(-c3ccccc3)c2)c1 +CNC(=O)c1c(-c2ccccc2)oc2ccc(O)cc12 +CNC(=O)c1ccc(NS(=O)(=O)C2=Cc3ccccc3CC2)cc1 +CCOC(=O)NCCC(=O)N(C)C(C)c1ccccc1F +CN(C)c1ccc(C2CCN(S(=O)(=O)c3cn[nH]c3)CC2)nc1 +COc1ccccc1C(=O)NCCn1nc(-n2cccn2)ccc1=O +CC(=O)Nc1cccc(C(N)c2nc(C)cs2)c1 +CC(Cc1ccsc1)NC(=O)Nc1ccc(F)c(F)c1 +C#CCNC(=O)c1cccc(S(=O)(=O)Nc2ccccc2OC)c1 +CC(CO)NC(=O)Nc1ccc(OC(C)C)cc1F +c1cncc(CC2C(OCC3CC3)CCN2C2CCOC2)c1 +CCOc1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)c(C)c1 +Cc1c(CNC(=O)c2nc(-c3cccs3)no2)cnn1C +CC=CCCNC(=O)Cc1c[nH]c2c(C)cccc12 +O=C(CCC1CCCCC1)NCC(=O)NC1CC1 +COCCOc1cccc(C2NC(=O)c3n[nH]c(C)c3N2)c1 +CNc1cc(C(=O)Nc2cc(F)ccc2F)ccn1 +NC(=O)c1cccc(CNCc2c(C3CC3)nc3sccn23)c1 +CC(C)c1cc(C(=O)NCc2ncn(C)n2)c(O)c(C(C)C)c1 +COCCOC(=O)c1cc(Br)ccc1F +Cc1nn(-c2ccccc2)c(C)c1NCc1cscn1 +CC(C)(CNC(=O)c1ccc2cc[nH]c2c1)c1ccncc1 +CN(C(=O)c1ccc(F)c(F)c1)C1(C#N)CCCC1 +O=C(CC1OCCc2sccc21)N1CCCCC1Cn1cccn1 +Cc1ccc(N(CCC#N)C(=O)COC(=O)c2cc(C)no2)cc1 +COc1ccc(OC)c(CN(C)C(=O)Nc2ccc3c(c2)COC3)c1 +COc1ccc(CNc2nccn(-c3cccc(OC)c3)c2=O)cc1 +CC(C)Cc1cc(C(=O)Nc2cnn(Cc3ccc(F)cc3)c2)no1 +Cc1nc(C)c(CC(=O)N(C)C(C)CC(C)C)c(=O)[nH]1 +O=C(NCc1ccccn1)C1(c2cccs2)CCCCC1 +Cc1cccc(C(=O)N2CCCc3cc(N)ccc32)n1 +CC(NC(=O)C1CCOC1)c1cccc(C(F)(F)F)c1 +Cc1ccc(C(=O)NC2CCN(C(=O)OC(C)(C)C)C2)o1 +CCOC(=O)c1nn(CC)c2c1CN(Cc1cccc(O)c1)CC2 +CCCCNC(=O)c1cccc(C(=O)NCCC)c1 +CC(c1nnnn1-c1ccccc1)N(C)CCc1ccccc1 +COc1ccccc1NC(=O)C(Sc1nnnn1C1CC1)C(C)C +CCCCNC(=O)COc1c[nH]c(CO)cc1=O +COc1ccc(S(=O)(=O)NCc2ccccc2)cc1C(N)=O +CCC(C)(C)NC(=O)C(C)NC(=O)c1ccccc1 +CC(C)Cc1cn[nH]c1C1CCCN(Cc2cccc(O)c2)C1 +CC(C1CC1)N(C(=O)Cn1cnc2ccsc2c1=O)C1CC1 +CCC(C)N(Cc1c(-c2ccccc2)noc1N(C)C(C)C)C(C)=O +COc1ccccc1N1CCC(CNC(=O)NC(C)C)C1 +Cc1ccc(NC(=O)NCc2cccs2)cc1N1CCCCC1=O +COc1cc(F)ccc1NC(=O)c1ccc(F)c(NC(C)=O)c1 +CCOC(=O)C1C2CCC(CC2=O)N1C(=O)OC(C)(C)C +C#CCN(Cc1ccco1)C(=O)CC1OCCc2ccccc21 +CC(C)NC(=O)C1CN(C(=O)c2cccs2)CC12CCOCC2 +O=c1[nH]cc(CN2CCc3n[nH]c(-c4ccccc4F)c3C2)c(=O)[nH]1 +Cc1ccc2cccc(NC(=O)C3CC(=O)N(C4CC4)C3)c2n1 +O=C1CC2CCC(C1)N2Cc1ccc(F)cc1F +Cc1cnn(C2CN(Cc3csc(Cc4ccccc4)n3)C2)c1 +CCS(=O)(=O)NC(C(=O)N1CCCC1)c1ccccc1 +Cc1nnc(N2CCN(CC(F)(F)F)CC2)c(C#N)c1C +CCCC(C)c1nnc(NC(=O)c2cc(Cl)c[nH]c2=O)s1 +Cc1noc(C2CC3CN(C(=O)c4ccco4)CC3O2)n1 +CC(C)NC(=O)CNC(=O)c1cc2ccccn2n1 +O=c1c2ccccc2nnn1Cc1cc(-c2cccs2)on1 +COCC(O)CN(C)C(=O)c1cccc(C)c1O +CCN(CCO)c1ncnc2sc(C(=O)OC(C)C)c(C)c12 +COc1cc(F)ccc1NC(=O)CCc1ccsc1 +COc1ccc(O)c(C(=O)N2CCN(c3ccccc3F)CC2)c1 +CCC(C(=O)N1CCCN(c2ncccn2)CC1)n1cccn1 +CNC(=O)NCC(=O)NC(C)(COC)c1ccccc1 +Cc1cccc(C(=O)NCCNC(=O)c2ccc(C(N)=O)cc2)c1 +O=C(C1CC=CCC1)N1CCN(S(=O)(=O)Cc2ccccc2)CC1 +CN(C(=O)CN1CCC(=O)CC1)C1CCCCC1 +Cc1cnn(CCC(=O)Nc2ccnc(Sc3ccccn3)c2)c1 +Cc1noc(C)c1CCc1nc(-c2ccccn2)no1 +O=C(Nc1cccc(O)c1)c1cn2cc(Cl)ccc2n1 +CCOc1ccc(F)c(C(=O)N2CCCCCC2)c1F +CC(C)n1c(SCc2ccccc2C#N)nnc1N(C)C +CC(C)COC(=O)c1ccc2[nH]cc(C(C)O)c(=O)c2c1 +N#CC(CC(=O)N1CCCCCC1)C(=O)Nc1ccc(Cl)cc1 +CCOc1ccc(C(=O)CCC(=O)Nc2ccccc2)cc1 +CCn1nc(C)c(CCC(=O)N2CC(C)OC(C)C2)c1C +Cc1cc(C)nc(CN(C)C(=O)c2cc(CN3CCOCC3)on2)c1 +C=CCNC(=O)c1ccccc1NC(=O)Cc1ccccc1F +CCCN(CC(F)F)C(=O)NCC(C)(C)c1ccncc1 +Cc1nc[nH]c1-c1nccn1C1CCCN(c2ncccn2)C1 +COC(=O)c1sc(NC(=O)Cc2ccc(F)c(F)c2)nc1C +COc1ccc(CNC(C#N)c2ccc(C)cc2)cc1 +CS(=O)c1nncn1CCCOc1ccc2c(c1)OCO2 +CCN(C)c1ccc(C(=O)Nc2cc(C)nn2C)cc1 +COc1ccccc1-c1ccc(C#N)c(=O)n1C(C)C(C)=O +CNC(=O)NCC(=O)N(C)CC12CC3CC(CC(C3)C1)C2 +CC(C)NC(=O)N1CCN(C2CCCN(C(C)C)C2=O)CC1 +Cc1nc(-c2cccs2)sc1CNC(=O)Cn1cncn1 +Cc1cccc(C(=O)NCCc2ncc(C)s2)c1 +COCC(C)NC(=O)c1cn(-c2ccc(Br)cc2)nn1 +CC(C)(C)C(=O)COc1ccc(-c2nnco2)cc1 +COc1cc(Nc2ccc(NC(=O)c3cccs3)cc2)nc(C)n1 +COc1cccc(CNC(=O)CCOc2ccccc2Cl)c1 +CSc1cc2c(cc1NC(=O)N(C)Cc1ccncc1)OCCO2 +CCN(CC)C(=O)COc1c(Cl)cccc1Cl +COc1ccc(CNC(=O)COc2ccc(C)c(C)c2)cc1 +O=C(CCn1cnnc1)N1CCCC1c1nc2ccc(F)cc2[nH]1 +N#Cc1cccnc1NCCOC(=O)c1cncc2ccccc12 +CC(C)N(C(=O)Cn1c(=O)[nH]c2ccccc21)c1ccccc1 +COCCNC(=O)c1cncc(-c2ccc(Cl)cc2)c1 +N#Cc1ccc(NCc2ccc(F)c(F)c2)cc1C#N +O=C(CCN1CCCCC1=O)NC1(c2cc(F)cc(F)c2)CC1 +N#CC1(NC(=O)CN2CCN(c3ncccn3)CC2)CCCC1 +CC(=O)Nc1cccc(-c2ccc(-c3nc(C)no3)cn2)c1 +CC(OCC(F)(F)F)C(=O)NCc1cccnc1 +Cc1ccc(NC(=O)CCNC(=O)C2CCC2)cc1 +Cc1nc2ccc(NC(=O)CCOCC3CCCO3)cc2o1 +COCC(=O)NC(C)c1nc(-c2ccc(Br)cc2)c[nH]1 +N#Cc1ccc(C(=O)OCC(=O)NCc2ccc(F)c(Cl)c2)cc1 +CCOCCOC(C)C(=O)Nc1ccc(F)cc1N +Cc1ccc(C(C)NC(=O)N2CCN(c3ncccc3C#N)CC2)o1 +Nc1ccc(F)cc1Oc1ncnc2sccc12 +CC(=O)c1sc(C(N)c2cccc(F)c2)nc1C +Cc1ccc(C(C)N(C)C(=O)c2ccncc2F)cc1 +CC1CCCC(C)N1C(=O)Cc1nc2cc(N)ccc2o1 +CCNC(=O)CNC(=O)Nc1cc(C)ccc1OC +CCS(=O)(=O)NCc1ccc(NC(=O)C(C)C)cc1 +CC(NC(=O)c1cnns1)C12CC3CC(CC(C3)C1)C2 +CCCCC1CCC(NC(=O)NCc2ncn(C)n2)CC1 +Cc1ccc(CNC(=O)C(C)Sc2ncc3ccccn23)cc1 +NS(=O)(=O)N1CCN(CCc2nc3ccccc3c(=O)[nH]2)CC1 +CCCC(C)N(C)S(=O)(=O)c1cccc(S(C)(=O)=O)c1 +COC(=O)C1(N(C)C(=O)c2cccc(C)c2)CCCCC1 +CCOc1ccc(NC(=O)NCc2ncn(C)n2)cc1C +Cn1cnc(CNS(=O)(=O)c2ccc(Cl)c(C#N)c2)n1 +Cn1c(NC(=O)C2CCN(S(C)(=O)=O)CC2)nc2ccccc21 +C=CCNC(=O)N1CC(c2nc(-c3cccnc3)no2)C1 +Cc1cc(NC(=O)c2ccc(C#N)c(C)n2)ncc1Br +CNC(=O)COc1ccc(Oc2ccccc2)cc1 +Cn1ccnc1-c1cn(CCC2=CCCCC2)nn1 +CC(NC(=O)c1ccc(=O)n(C)n1)c1ccc(Cl)c(Cl)c1 +O=C(CCc1nc2ccccc2[nH]1)N1CCCC1c1ccccc1 +O=C(NCc1nc(C2CC2)no1)Nc1ccc(F)cc1F +COc1cccc(N2CCN(Cc3nnc(C4CC4)o3)CC2)c1 +Cc1ccc(C)c(NC(=O)NCCn2cc(Br)cn2)c1 +CC(Cc1ccsc1)NC(=O)C(NC(N)=O)C(C)C +COc1ccc(OC)c(NC(=O)Cc2ccc(C)c(OC)c2)c1 +N#Cc1nccnc1N1CC(n2cc(-c3ccccc3)nn2)C1 +Cc1cc(C)c(NC(=O)CN(C)S(=O)(=O)C(F)F)c(C)c1 +Cc1sc2ncnc(N3CCOCC3)c2c1-c1ccccc1 +Cc1cccc2c1N(Cc1ccc(C(=O)N(C)C)[nH]1)CC2 +Cc1ccc(-c2cc(NC(=O)OC(C)(C)C)[nH]n2)cc1 +Cc1nc(CNC(=O)NCc2nnc(-c3ccccc3)s2)oc1C +COCCNC(=O)C(N)c1cccc(Cl)c1F +COCCCNC(=O)C(N)c1ccc(F)cc1C +N#Cc1ccccc1OCC(=O)Nc1ccccc1N +Cc1cc(C)nc(C(C#N)C(=O)c2ccc(N3CCOC3=O)cc2)n1 +Cc1cc(C(=O)COC(=O)c2ccc[nH]2)c(C)n1CC(F)(F)F +CC(=O)Nc1sc(C)c(C)c1C(=O)NC(C)C +COc1ccc2c(c1OC)C(=O)OC2Nc1cccnc1 +CC(=O)NCc1ccc(-c2csc(NC(=O)c3ccco3)n2)o1 +COC(=O)Cc1csc(NC(=O)C2(c3cc(C)cc(C)c3)CC2)n1 +Cn1cc(C2CCCN2C(=O)CCc2cscn2)cn1 +CCc1ccccc1OCC(=O)NCC1COc2ccccc2O1 +COC(=O)c1nnn(Cc2c(Cl)cccc2Cl)c1C(=O)OC +O=C(Oc1ccc(-n2cnnn2)cc1)c1ccc(NC(=O)C2CC2)cc1 +CC(C(=O)Nc1ccccc1SC(=O)N(C)C)c1ccsc1 +COc1ccccc1CC(=O)N1CCC(c2nncn2C(C)C)CC1 +CCCc1nnc(NC(=O)c2ccnc3ccccc23)s1 +O=C1CCc2cc(C(=O)NCc3ccc4c(c3)OCO4)ccc2N1 +COc1ccnc(N(Cc2ccco2)CC2CCCO2)n1 +O=C(Nc1cc(-c2ccccn2)no1)c1ccc(Cl)cc1 +CCOc1ccc(C(=O)N(C(C)C)C2CCC2)cc1 +CCOCC1CCN(C(=O)Cc2csc(C)n2)CC1 +CNC(=O)N(Cc1cccnc1)Cc1ccccc1Cl +Cc1n[nH]c(C)c1CNC(=O)COc1ccccc1Br +CCc1cccc(CC)c1NC(=O)CN1CCOc2ccc(N)cc21 +Cc1cc(C(=O)N2CCC(c3ccsc3)CC2)no1 +Cc1nc(C2CCN(C(=O)Nc3ccccc3C(C)C)CC2)n[nH]1 +N#CC1(C(=O)Oc2ccc(NC(=O)C3CC3)cc2)CCCC1 +Cc1cc(Cl)ccc1OC(C)C(=O)NCCNS(C)(=O)=O +COCCN(CCOC)C(=O)c1cc(C#N)cn1C +O=c1[nH]c(NCc2cccc(F)c2)nc2ccccc12 +CCOC(=O)c1cnc(-c2ccccc2OCC)nc1N +CS(=O)(=O)NC1CCN(C(=O)NCc2cccc(Cl)c2)CC1 +Cc1ccncc1NC(=O)Nc1cccc(OC(F)F)c1 +Cc1cc(Cl)ccc1OCCCNC(=O)Cn1ccccc1=O +Cc1ccc(NC(=O)C(C)NC(=O)Nc2ccccc2)c(C)c1 +O=S(=O)(c1ccc(N2CCCC(CO)C2)cc1)C(F)F +CCc1onc(C)c1NC(=O)N1CC2CCCC2C1 +CCOC(=O)N1CCN(C(=O)c2ccnn2C)CC1 +O=C(NCc1cccc2c1OCO2)c1ccnc(-n2cncn2)c1 +CCCNC(=O)CNc1cc(C(=O)OC)c(F)cc1Br +Cc1nc(C(C)(C)NC(=O)c2ccccc2F)sc1C +O=C(Cc1ccc(-n2cnnn2)cc1)OC1CCCCCC1 +O=C(c1cnccn1)N1CCOC2CC(COc3ccccn3)CC21 +COc1ccc(N)cc1CNC(=O)c1ccc(Cl)cc1F +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)N(C)Cc1ccsc1 +CSc1cccc(C(=O)Nc2nc(C)c(C)s2)c1 +Cc1ccc(C(=O)NCCCCN2CCOCC2)cc1F +Cc1cc(NC(=O)NC(C)C)n(-c2nc(-c3ccco3)cs2)n1 +Nc1ccc2c(-c3cnc4ccccc4c3)n[nH]c2c1 +COC(=O)c1cccc(COC(=O)c2ccc(CO)cc2)c1 +O=C1CCN(Cc2cc(=O)[nH]c(-c3cccc(Cl)c3)n2)CC1 +COc1cc(C2CC(=O)Nc3c2ccc2ccccc32)ccc1O +Cc1nc2ccc(C(=O)NC3CCC(C)CC3)cc2nc1C +CC(C)NC(=O)CS(=O)(=O)c1ccc(C(F)(F)F)cn1 +CC(C)CCNC(=O)c1cc(C#CCO)ccc1F +O=C(NCC1CC1)C1CN(C(=O)c2ccccc2)CC12CCOCC2 +COc1ccc(-c2ccc(C(C)=O)c(C)n2)c(OC)c1 +Cc1cccc(C)c1NC(=O)COc1ccc(F)c(Cl)c1 +CCCS(=O)(=O)NCc1ccc2c(c1)OCO2 +CNC(=O)c1cccc(NC(=O)CC2CCC(C(F)(F)F)CC2)n1 +CC(C)C(NC(=O)c1ccco1)C(=O)Nc1ccncc1 +CCN(Cc1cc(Cl)ccc1OC)Cc1ncnn1CC +COCCOC(=O)C1=C(C)Nc2ncnn2C1c1ccco1 +CCc1nnc(NC(=O)CCn2cncn2)s1 +CC(=O)c1cccc(OC(C)C(=O)NC(C(N)=O)C(C)(C)C)c1 +COc1ccc(OC)c(CSc2nnc(C)n2N)c1 +c1ccc(-c2nc3ccccc3n2CCc2ccncc2)nc1 +CCc1ccc(C(C)Nc2ccc(=O)n(C)c2)cc1 +OCc1cc(F)cc(CO)c1OCc1nc(-c2ccco2)no1 +CCCCCNS(=O)(=O)c1c(N)nc2ccccn12 +COC(=O)C(C)Nc1ccc2c(c1)CCN2C(C)=O +Nc1cc(Cl)ccc1C(=O)OCC(=O)N1CCOCC1 +CCn1cnnc1CNC(=O)c1ccnc(SC)c1 +CNc1ccc(Cl)c(C(=O)N2CCC(CO)CC2)n1 +O=C(Nc1cc(-c2ccccn2)no1)c1ccco1 +O=C(NCc1cccnc1)Nc1ccc(Br)cc1 +C#Cc1cccc(NC(=O)CNS(=O)(=O)Cc2cccc(F)c2)c1 +CCOC(=O)CN(C)C(=O)c1ccnc(N(C)C)c1 +O=C(NCCNc1ccc2nnnn2n1)c1ccoc1 +O=C(Nc1ccc(NC(=O)c2ccc(F)cc2F)cc1)c1ccco1 +CC1(C)C(NC(=O)NCc2cccc(-n3ccnc3)c2)C2CCOC21 +CCC1CN(C(=O)c2c[nH]nc2-c2ccc(F)cc2)CCO1 +Cc1nc(CN(C)C(=O)c2cscn2)cs1 +C=CCn1cc(CN2CCN(c3ncc(Cl)cn3)CC2)c(C)n1 +CCN(C(=O)c1[nH]c(C)c(C(C)=O)c1C)C(C)C(C)C +Cc1ccnc(NC(=O)C2CCCN2C(=O)NC2CCCCC2)c1 +Cc1cc2nc(C)c(CCC(=O)Nc3ncc(C)s3)c(C)n2n1 +COC(=O)CN(C)C(=O)c1cccc(Br)c1 +N#Cc1nnn(CCCOc2ccccc2)c1C(F)(F)F +COc1cccc(NC(=O)NCCCN2CCOCC2)c1 +CC(O)CCc1nc2c(Br)cc(N)cc2[nH]1 +Cc1ccc(NCc2ccccn2)cc1Br +Cc1ccccc1CNC(=O)c1ccc(NS(C)(=O)=O)c(C)c1 +CC(C)OCCOC(=O)c1cccc(-n2cccn2)n1 +O=C(CNC(=O)c1cccs1)c1ccc(Br)cc1 +Cc1ccccc1Cn1nc(C)c(NC(=O)c2ccoc2C)c1C +CCCN(C)S(=O)(=O)c1cc(Cl)ccc1C#N +Cc1noc(C)c1C(C)NC(=O)C(C)Oc1cccc(Cl)c1 +CC(NC(=O)c1ccoc1)c1ccccc1OC(F)F +CCN(CCC#N)C(=O)c1cnn(-c2ccncc2)c1C +CCOC1CC(N(C)C(=O)Nc2c(C)noc2CC)C1(C)C +CCN(CC)C(=O)c1sc(C(C)(C)C)nc1C +CC(=O)N1CCN(c2ncccc2-c2nnc(C(C)C)o2)CC1 +Cc1csc(CCNC(=O)c2ccccc2Cl)n1 +CNC(=O)c1cccc(OC(=O)c2csc(-c3cnn(C)c3)n2)c1 +CCC(CO)NC(=O)NCc1ccnc(OC(C)(C)C)c1 +Cc1cccnc1CN1CCN(Cc2cnc(N(C)C)s2)CC1 +Cc1csc(C2CCCN(C(=O)c3ccc[nH]3)C2)n1 +COc1ccc(CN2CCN(C(=O)CCc3ccccc3)CC2)cn1 +Cn1cccc1C(O)CNC(=O)c1cc2ccccc2oc1=O +CCOC(=O)c1cc(S(=O)(=O)Nc2ccccc2CC)cn1C +COc1ccc(Cl)cc1C(=O)CN1CCN(C(C)=O)CC1 +O=C(Nc1ccc(S(=O)(=O)CC2CCCO2)cc1)C1CC1 +CCCCNc1nc(C)nc2sc3c(c12)CCC3 +O=C(Cc1c[nH]c2ccccc12)NC1CCc2c(O)cccc21 +COc1ccccc1CNC(=O)Cc1cnn(-c2ccccc2)c1 +COCCn1cc(C(=O)Nc2ccc3[nH]ccc3c2)c2ccccc21 +Cn1nc(CNC(=O)c2cc3ccccc3oc2=O)cc1C1CC1 +O=C(Nc1cccc(-n2cnnn2)c1)c1cccc2[nH]ccc12 +CCc1ccc(S(=O)(=O)NCC(=O)Nc2ccccc2)s1 +Cc1ccccc1CNC(=O)NC(C)c1ccncc1 +COc1cc(NC(=O)c2ccccc2)ccc1NC(C)=O +COc1cccc(CNC(=O)N2CCCC(NS(C)(=O)=O)C2)c1 +CCC(=O)Nc1ccc(C)cc1-c1nc2ccc(C)cc2[nH]c1=O +Cc1noc(C)c1CC(=O)NCc1nnc2ccccn12 +CCCc1oc(C)c(C)c1-c1csc(NCCOC)n1 +O=C(CSc1nnnn1C1CCCC1)N1CCc2ccccc2C1 +O=C(NCCCOC1CCCCC1)c1cnc2sccn2c1=O +CN1C(=O)c2oc3ccc(Cl)cc3c(=O)c2C1c1cccs1 +COC(=O)CCC(=O)Nc1ccc(Cl)c(Br)c1 +Cc1cnc(C(=O)Nc2cc(-n3nnnc3C3CC3)ccc2F)cn1 +CCOc1ccccc1OCCCC(=O)N1CCC(C)CC1 +OCCOc1ccccc1OCc1ccc(F)c(Br)c1 +Cc1nc(N(C)C)sc1CN1CCN(C)C(=O)C1(C)C +COc1ccc(C(=O)Nc2cccc(OCCCC#N)c2)nn1 +Cc1ccc(-n2cc(C#N)cn2)c(Br)c1 +Cn1cnc2cc(CNC(=O)C3CCCC3)ccc21 +CNC(=O)CNC(=O)c1cc(OC)ccc1Br +CN(CC(=O)N1CCCC1)C(=O)c1ccc(Br)cc1O +CC(=O)N1CC(C(=O)NCc2nc(-c3ccccc3)no2)C1 +CC(C)N(Cc1ccccc1)C(=O)c1ccc(-n2ccnc2)nc1 +O=C(Nc1cn[nH]c1)Nc1cccc(Cl)c1Oc1cccnc1 +O=C(CNc1nccs1)c1c[nH]c2ccccc12 +CCOC(=O)C(O)Cc1cnc(C(F)(F)F)nc1 +CC(Oc1cccc(Cl)c1)C(=O)NCCc1cccnc1 +CC(=O)NCc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +Cc1cc(C(=O)N2CCOCC2C)c(C)n1-c1nccs1 +Fc1ccc(-c2noc(CN3CCOCC3C3CC3)n2)cc1F +CC(Cc1ccccc1F)NC(=O)c1cn(C)nc1C(F)(F)F +Cc1ccccc1CC(C)(C)NC(=O)COc1ccc(C(N)=O)cc1 +Cc1cc(C)c(NC(=O)CN(C)C(=O)NCc2ccco2)c(C)c1 +CC(C)=C1CCC2(C)OC(=O)C(Cc3ccccn3)C12C +O=C(NCC(=O)N1CCCC1)c1cccc(Br)c1 +CCC(=O)N1CCc2ccc(NC(=O)c3cccc(C)c3)cc2C1 +Cc1ccc(F)c(-n2nnnc2Cn2cnc3c(cnn3C)c2=O)c1 +N#CC1(C#N)C(c2cccs2)C(C(N)=O)N2C=Cc3ccccc3C21 +Cn1cccc1C(=O)N1CC2CCC1CN(C(=O)c1cnccn1)C2 +O=c1[nH]c2c(-c3ccccc3)nnn2c2c1nnn2Cc1ccccc1 +Cn1cc(CNC(=O)NC(C(N)=O)c2ccccc2)cn1 +Cc1nnc(NC(=O)CCc2nc3c([nH]2)c(=O)[nH]c(=O)n3C)s1 +O=C(NCC1CCN(c2ccc(Cl)cc2)C1)C1CCC1 +CC=CCOC(=O)c1c(F)ccc(OCC)c1F +CCOC(C)C(=O)N1CCN(c2ccnc(-c3ccccc3)n2)CC1 +CCCN(CCC)C(=O)c1ccnc(SCC)c1 +O=S(=O)(NC1CCc2cc(F)ccc21)c1ccc(F)cc1 +CC(NC(=O)COc1ccccc1)C(=O)N1CCCC1 +Cc1cnc2c(c1SCc1ccccn1)c(=O)n(C)c(=O)n2C +CC(C)(C)c1nnc(Cn2ccc(=O)c3sccc32)o1 +Cc1ccc(OS(=O)(=O)c2cn(C)c(C)n2)c(Cl)c1 +c1cc(-c2cnc(NC3CC3)nc2C2CCCO2)ccn1 +CCN(Cc1nnc(C2CC2)o1)c1cccc(CO)c1 +COc1cc(OC)cc(N2CCN(C(=O)C(C)C)C(C)C2=O)c1 +CCS(=O)(=O)N1CC(S(=O)(=O)c2ccc(OC)cc2)C1 +N#Cc1nccnc1NCC1CC(=O)Nc2ccccc21 +CCOC(=O)c1cc(OC(C)=O)c2ccc(OC)c(OC)c2c1 +COc1ccccc1N1CC(C(=O)OCCc2cccs2)CC1=O +OCCN1CCN(c2nc(-c3ccccc3)no2)CC1 +CC(O)CN1CCN(C(=O)c2cccs2)CC1 +CN(C)c1ccc(C(=O)N2CCC(c3nc4ccccc4o3)CC2)cc1 +O=C(Cc1csc(-c2ccsc2)n1)NCC1CCOC1 +CCC(C)(C)NC(=O)c1ccn(-c2ccccc2F)n1 +C=CCNc1nnc(SCc2noc(C(C)(C)C)n2)s1 +O=S(=O)(CCOc1ccccc1)NCc1ccncc1 +CC(CC#N)NC(=O)c1ccc(F)c(C(F)(F)F)c1 +Cc1nc2ccccc2n1CCNc1nccn2cnnc12 +Cc1cccc(NC(=O)c2cc(=O)c(OCc3ccccc3)co2)n1 +CCCC(=O)Nc1ccc(NC(=O)c2cc(C(C)C)n[nH]2)cc1OC +COC(=O)CCCN(C)S(=O)(=O)c1ccccc1F +COc1ccccc1C1(C(=O)N2CCN(CC(C)O)CC2)CC1 +COc1ccc(CN(C)C(=O)c2ccnc(OC3CCC3)c2)cc1C +Cc1ccc(Cl)cc1S(=O)(=O)N1CCC2(CC1)OCCCO2 +COC(=O)Cc1c(C)nc(N2CCN(c3ccccc3)CC2)[nH]c1=O +Cc1ccc(S(=O)(=O)CC(=O)N(C2CC2)C(C)C2CC2)cc1 +Cc1ccc(OCCC(=O)Nc2ccccc2-n2cnnn2)c(C)c1 +COc1cc(C(=O)Nc2ccc(C)c(C)c2)cc(OC)c1OC +N#Cc1ccc(NC(=O)N2CCOCC2C2CC2)cc1Cl +COc1cccc(OCC(O)CNc2ccccc2F)c1 +Cc1ccc(S(=O)(=O)NCc2csc(C3CC3)n2)c(C)c1 +COc1ccc(S(=O)(=O)NCC(O)Cc2ccccc2)cc1 +CC(C)CC(=O)N1CCc2ccc(Cl)cc2C1 +O=C(Cc1ccc(F)cc1)N1CCN(C(=O)CC2(O)CCCC2)CC1 +COc1ccccc1NC(=O)CN1CC(C)Oc2ccc(N)cc21 +Fc1ccc(NCc2n[nH]c(-c3ccccc3)n2)cc1 +Cc1cc(CN(C)C(=O)CSc2cccc(C(F)(F)F)c2)no1 +Cn1cc(NC(=O)C2CCCC(C(F)(F)F)C2)cn1 +CCC1CCC(NC(=O)NCC(C)(C)N2CCOCC2)CC1 +Cc1cc(C(=O)N2CCC(Oc3ccccc3)CC2)nn1C(C)(C)C +Cc1cccc(OCC(C)NC(=O)CN2CCCS2(=O)=O)c1 +COc1ccccc1OCC(=O)Nc1c[nH]nc1C +COC(=O)c1ccc(CNC(=O)c2ccc(C#N)cc2)cc1 +Nc1cccnc1SCc1cc(Br)cs1 +CCCNC(=O)c1noc2c1CCc1sccc1-2 +Cc1ncsc1CCC(=O)N(C)Cc1nc2ccccc2s1 +Cc1cc(C)c(NC(=O)NCCNC(=O)c2ccccc2O)c(C)c1 +O=C(CSc1ccc(Br)cc1)NCC(F)(F)F +CC(C)(C)CC(=O)N1CCN(S(=O)(=O)c2cccs2)CC1 +CC(C)N(C)C(=O)c1ccc(OC(F)(F)F)cc1 +O=C(c1cnc(C2CCCO2)s1)N1CCC(O)(C(F)(F)F)C1 +N#Cc1ccc(Cl)c(NC(=O)c2ccc(-n3cccn3)cc2)c1 +CCc1ccccc1OCC(=O)Nc1cc(NC(C)=O)ccc1OC +CCOc1ccc(OCCNC(=O)NC2CC2)cc1 +COCC(C)(C)CNC(=O)C12CCC(C)(C(O)C1)C2(C)C +Cc1cccc(C2CCCN2C(=O)C(C)NC(N)=O)c1 +O=C(C1CCCC1)N1CCN(c2ncc(Br)cn2)CC1 +Cc1ccc(F)cc1-n1ccn(CC(N)=O)c(=O)c1=O +CN(Cc1ccccc1)S(=O)(=O)NCC(O)C1CC1 +CC(C)C(Oc1cccc(Cl)c1)C(=O)NCc1ccnn1C +COc1cc(C(=O)N2CCCCC2)ccc1OCc1csc(C)n1 +CC1CCC(NC(=O)c2ccccc2SCC(=O)N(C)C)CC1 +O=C(c1ccc2ccccc2n1)N(Cc1ccccc1)C1CC1 +Cc1c(C(=O)Nc2cccc(S(C)=O)c2)cnn1-c1ccncc1 +O=C(Nc1n[nH]c2ccccc12)c1n[nH]c(=O)c2ccccc12 +Cc1ccc(C)c(C(=O)Nc2ccccc2SCC(N)=O)c1 +CC(NS(=O)(=O)N(C)C)c1cccc2ccccc12 +Cc1ccccc1CNC(=O)NCC(CC(C)C)N1CCOCC1 +CN(Cc1ccccc1)C(=O)c1cc(=O)c(OCc2ccccc2)co1 +CC1CCC(NC(=O)Cc2c(F)cccc2F)CC1 +Nc1ccc2c(n1)NC(=O)CC2c1ccccc1OC1CCCC1 +Cc1cccc(CNC(=O)CCC(=O)c2ccc(F)cc2F)c1 +Cn1nc(C(=O)Nc2nc(CC(N)=O)cs2)ccc1=O +CC(=O)Nc1cc(NC(=O)N2CC3CC=CCC3C2)c(F)cc1F +CN(C)S(=O)(=O)c1ccc(-c2nc(-c3cnn(C)c3)cs2)cc1 +COCCN1CC2CCN(c3ncccn3)CCC2S1(=O)=O +CC(=O)c1c[nH]c(C(=O)OC(C)c2nc3ccccc3c(=O)[nH]2)c1 +CCn1ccnc1N1CCN(C(=O)c2ccc(OC(C)C)cc2)CC1 +COC(=O)c1sc2nc(-c3cccs3)ccc2c1N +Cc1cccc(N2CC(c3noc(-c4cccc(C#N)c4)n3)CC2=O)c1 +COc1ccc(CNCCN2CCOCC2)cc1Br +O=C(Nc1cccc(F)c1)c1ncc(-c2ccncc2)s1 +Cc1nc(Nc2ncccc2C)cc(C2CCN(c3ncccn3)C2)n1 +CCCc1n[nH]c(SCCn2nc(C)cc2C)n1 +COc1cc(C)c(-c2cn3cccc(N)c3n2)cc1C +Cc1ccc(C2COCCN2C(=O)CCC2CCCO2)o1 +COc1cccc(NC(=O)C2CCN(C(=O)NC3CC3)CC2)c1 +CC1C(=O)N(c2ccc(F)cc2F)CCN1Cc1ccccc1F +COC(=O)NCCOC(=O)C1(c2ccc(Cl)cc2)CCC1 +Cc1ncccc1C(=O)NC1(c2ccccc2)CCCC1 +NC(=O)CNC(=O)c1cccc(N2CCCC2=O)c1 +O=C(C1CCOC1)N1CCC(c2nc(-c3ccccc3)no2)CC1 +Cn1cc(CNc2ccc(-c3cnco3)cc2)cn1 +Cc1ccc(C(O)(CCNC(=O)Nc2ccncc2)C(F)(F)F)o1 +CNS(=O)(=O)c1cc(C(=O)NC2(C)CCC(C)CC2)n(C)c1 +Cc1c(C(=O)NC(C)C)sc2nc(-c3ccccc3)cn12 +CCS(=O)(=O)NC(C)c1ccc(F)cc1Cl +CC(C)n1cc(Br)cc1C(=O)N1CCN(C)CC1 +Cc1cc(C)n(CC2CCCN2C(=O)C2CCCO2)n1 +N#CCC(=O)NCc1nc(-c2ccc(Br)cc2)n[nH]1 +CCc1nccn1-c1cccc(C2CCCN2C(=O)c2cnccn2)n1 +CC(=O)Nc1ccc(C)cc1NCC(=O)N(c1ccccc1)C(C)C +CC(=O)Nc1cccc(NC(=O)N2CCCCC2c2cn[nH]c2)c1 +CCCCN(CC)c1ccc(S(=O)(=O)N2CCOCC2)cn1 +Cc1ccc2nc(SCc3c(C)noc3C)n(C)c(=O)c2c1 +CC(Oc1ccc(F)c(F)c1)C(=O)NCc1ccco1 +Cc1nnnn1-c1cccc(NCc2cnn(Cc3ccccc3)c2)c1 +CC(C)(C)OC(=O)N1CCCC(C(=O)OC2CCCCC2=O)C1 +COc1ccccc1NS(=O)(=O)c1cc(C)ccc1OC +Cc1ccccc1C(NC(=O)N1CCCC(CC(N)=O)C1)C(C)C +c1nc(N2CCn3c(nnc3C3CC3)C2)c2cc[nH]c2n1 +CC(C)(C#N)NC(=O)c1cccc(OCc2ccccc2)c1 +COc1ccc(CNc2cccc(CN3CCCCC3=O)c2)cc1F +O=C(Nc1ccc(Oc2cccnc2)nc1)C1(c2ccccc2F)CC1 +CCOC(=O)c1csc(CNC(=O)OC(C)(C)C)n1 +CC(=O)NC(Cc1ccccc1)C(=O)Nc1ccccc1C +CC(Oc1ccccc1C(F)(F)F)C(=O)n1ncc(C#N)c1N +CCOc1cn(-c2ccccc2)nc1C(=O)Nc1ccc(C(C)=O)cc1 +CN1CCn2c(nnc2C(=O)Nc2ccc(F)cc2)C1 +Cc1ccccc1-n1ccnc1SCCNS(C)(=O)=O +CC(=O)Nc1cccc2c(S(N)(=O)=O)cccc12 +CC(C)COC(=O)CCn1ncc(=O)c2ccccc21 +Cc1ccccc1CS(=O)(=O)Nc1ccc(F)cc1 +Cc1ccc(NC(=O)N2CC(C(N)=O)CCC2C)s1 +COc1ccc(C(=O)NC(CO)(CO)CO)cc1OC +N#Cc1cn(CC(=O)NCCCc2ccccc2)c2ccccc12 +Nc1c(Nc2ccc(Cl)cn2)ncnc1N1CCOCC1 +CCOc1cc(C)c(C(O)CCC(=O)NC(C)(C)C)cc1C +NC(=O)c1cccc(C(=O)Nc2nc3c(s2)CCCCC3)c1 +O=C1CCN(S(=O)(=O)c2ccc3c(c2)Cc2ccccc2-3)CC1 +CC(=O)N1CCCN(S(=O)(=O)N(C)C2CCCCC2)CC1 +COc1ccc(F)cc1NC(=O)COc1ccccc1 +CNC(=O)c1ccc(CSc2nnc(C3CC3)s2)cc1 +CCCC(=O)N(CCn1nc(C)cc1C)c1nc2ccccc2s1 +CC(C)C(C)NC(=O)COc1ccc(N)cc1Cl +O=C(c1ccc2c(c1)OCCO2)N1CCc2cc(F)ccc2C1 +COc1cc(OC)c(-c2ncc(N)cn2)c(OC)c1 +FC(F)(F)c1nnc2ccc(NCCc3ccccn3)nn12 +COc1cc(NCc2ccc(C)cc2)nc(C(C)C)n1 +O=C(OCCn1cccn1)c1cnc(-c2ccco2)s1 +Cc1cccnc1CNC(C)c1ccc(C#N)cc1 +Cc1nccn1Cc1cccc(CNC(=O)NCC(C)(C)C(N)=O)c1 +CN(C(=O)c1ccccc1Cl)c1nnc(-c2cccnc2)s1 +CNC(=O)C1(C)CN(C(=O)c2cc(OC)cc(OC)c2)CCO1 +O=C1CCCN1Cc1noc(-c2ccc(Cl)cc2)n1 +CCCc1ccc(C(=O)NCc2ccc(N3CCCC3=O)cc2)cc1 +COc1cccc(C(=O)CSc2nnc(-c3ccco3)o2)c1 +CCOC(=O)CSc1nnc(-c2ccc[nH]2)o1 +O=C(NCc1cc2ccccc2o1)c1n[nH]c2ccccc12 +Cc1ccc(N2CCN(C(=O)c3cccc4ncccc34)CC2=O)cc1 +Cc1cccc2c1ncn1c(=O)n(CC(=O)NC3CCCC3)nc21 +COc1ccnc(NC(=O)CNC(=O)c2cc3c(s2)CCCC3)c1 +Cc1cc(CNS(=O)(=O)c2cccc(-n3cnnn3)c2)no1 +CCn1nnnc1-c1cccc(NC(=O)N2CCCC(O)C2)c1 +CCC(C)NC(=O)CN1C(=O)C(C(C)C)Oc2ccc(N)cc21 +Cc1c(C(=O)NCc2ccnc(OC3CCC3)c2)cnn1C +O=C(Cc1n[nH]c2cc(Cl)ccc12)NCC(=O)NC1CCCCC1 +Nc1cccc(OCCCc2nc(-c3ccccn3)cs2)c1 +OCc1cc2ccccc2nc1-c1ccc(-c2ccn[nH]2)cc1 +CC(=O)Nc1ccc(O)c(C(=O)N2CCC(Nc3ccccc3)C2)c1 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)NC(C)C +O=C(NCc1ccco1)c1nc(-c2ccncc2)no1 +C=CCNc1nnc(SCC(=O)N2CCCC(C)C2)s1 +COC(=O)N1CCCN(C(=O)c2cc(C)cc(C)c2O)CC1 +FC(F)Oc1cccc(NCc2cnc(N3CCOCC3)nc2)c1 +CN(Cc1ccccc1)C(=O)CCNC(=O)NC1CCCCC1 +CCC(NC(=O)CNC(=O)OC)c1ccccc1OC +N#Cc1c(Br)cccc1C(F)(F)F +Cc1csc(CNC(CC#N)c2ccccc2)n1 +O=C(Cc1ccccc1F)N1CCCC1Cn1nnc2ccccc21 +CC1Cc2ccccc2N1Cc1ccoc1C(=O)NCC(N)=O +CCNC(=O)CNC(=O)NCC(C)(C)c1ccccc1 +Cc1ccc(-n2nnnc2NCCCc2cn[nH]c2C)cc1 +CCNC(=O)C1CCCN(S(=O)(=O)c2cc(F)ccc2C)C1 +CCN(CC)c1ccc(C(=O)Nc2cn(C)c(=O)cc2C)cc1 +CN(CC1CCCCC1)C(=O)c1cc(Br)cnc1N +CCC(NCC(N)=O)c1ccc(Br)cc1 +Cc1cccc(C)c1NC(=O)CCSc1ccccn1 +COc1ccc(F)c(NC(=O)c2ccc(C(N)=O)nc2)c1 +COc1ccc(NC(=O)CCNS(=O)(=O)c2ccc(C)cc2)cn1 +CC(C)NC(=O)CCCNC(=O)Cc1n[nH]c2c(Cl)cccc12 +Cc1nc(-c2cccc(NCc3cnn(Cc4ccccc4)c3)c2)n[nH]1 +Cc1occc1C(=O)NC1CCN(C(=O)Cc2ccc[nH]2)CC1 +NC(=O)CNC(=O)c1ccc(-c2ccc3c(c2)OCCO3)s1 +Cc1cc(NC(=O)c2nccc3c(N)cc(Cl)cc23)ccn1 +Cc1cc(C(=O)Nc2nnc(-c3cccc(F)c3)o2)n(C)n1 +O=C(Nc1ccc(F)cc1)Nc1ccc2c(c1)OCO2 +Cc1n[nH]cc1CNS(=O)(=O)c1cccc(Cl)c1F +Cc1ccccc1-n1c(=O)[nH]c2ccccc2c1=O +NS(=O)(=O)N1CCN(C(=O)Nc2ccccc2)CC1 +CC(c1ccc(S(N)(=O)=O)cc1)N(C)C(=O)CC(C)(C)C +CC(C)OC(=O)c1nnn(CC(=O)N2CCCCC2)c1N +CC(=O)NC1CCCN(C(=O)NCc2ccc3c(c2)OCO3)C1 +CNC(=O)c1ccsc1NC(=O)CCSc1ccccc1 +Cc1ccccc1CNC(=O)COc1cccc2c1CCC2=O +C=C(C)C1CC=C(CN2CCN(C(C)=O)CC2)CC1 +Cc1ccc(-n2cccn2)c(CNC2COc3ccccc3C2)c1 +CC(C)OCCCNC(=O)NC1CCSc2c(F)cccc21 +C=CCn1c(C)nnc1SCC(=O)NC1CCCC1 +Cc1cc(C2CCCN2C(=O)NCCCOCC2CCCO2)on1 +COc1ccc(NS(=O)(=O)c2cn[nH]c2)c(OC)c1 +O=C(NCc1ccnc(OCc2ccccc2)c1)c1ccc[nH]1 +CC(=O)N(CCc1ccccc1)CC(=O)Oc1ccc2c(c1)CCC2 +Cc1noc(CCC(=O)N2CCOC(C(=O)NC3CCCC3)C2)n1 +Cc1cccc(C(=O)NC(C)Cc2cccc(Cl)c2)n1 +CNC(=O)c1cc(C)ccc1NCc1nccn1Cc1ccccc1 +COc1cccc2cc(C(=O)N(C)CC3CCCO3)oc12 +O=C(COc1nnc(-c2ccccc2)o1)N1CCc2sccc2C1 +CC(O)c1cnc(N(C)Cc2ccccc2Cl)s1 +Cc1ccc2ncc(C(=O)Nc3cc(C)on3)c(=O)n2c1 +CC(=O)Nc1cccc(NCC(=O)Nc2ccc(C)c(Cl)c2)c1 +COc1ccccc1C(=O)Nc1cccc(C(C)=O)c1 +NC(=O)CN1CCCC1c1cncc(-n2ccnc2)n1 +CCc1noc(C)c1C(=O)NC(C)C(=O)NC(C)CC +C=CCNC(=O)COc1cccc2c(=O)n(CCC)ccc12 +NC1C(=O)N(Cc2ccc(F)cc2)c2ccc(Br)cc21 +CCCCNC(=O)CC1C(=O)NCCN1Cc1cccc(F)c1F +Cn1nccc1CNC(=O)Nc1ccccc1OC(F)F +Cc1cccc(C(=O)N(C)Cc2c(C)noc2C)c1O +Cc1ccc(NC(=O)c2cccc(-c3nnnn3C(C)C)c2)cc1 +CCNC(=O)Nc1sc2c(c1C(=O)OCC)CCCC2 +CS(=O)(=O)N1CC(C(=O)NC2CCCCC2)Oc2ccccc21 +O=C(Nc1nc2c(s1)CN(S(=O)(=O)C1CC1)CC2)C1CC1 +CCOC(=O)c1ccc(OC(C)=O)c(Br)c1 +Cc1ccc(NCC(=O)N2CCCC(C(N)=O)C2)cc1C +COc1ccc(NC(=O)c2c(F)cccc2F)cc1 +CN(C(=O)Cc1csc(-c2ccoc2)n1)c1ccccn1 +CC(C)n1nc(CC(=O)Nc2nccs2)c2ccccc2c1=O +Cc1cc(C)n(-c2ccc(C(=O)NCC(O)c3ccco3)cc2)n1 +Clc1cccc(-c2nnc(CSc3nccn3C3CC3)o2)c1 +Cc1cc(=O)n(CC(=O)Nc2ccccc2C)c(N2CCOCC2)n1 +CC(c1nc(-c2ccccc2)no1)N1CCN(CCCC#N)CC1 +Cc1cc(C(=O)Nc2ccc(C(F)(F)F)cc2)on1 +CN(C)C(=O)N1CCC(C(=O)N(C)CCC#N)CC1 +CCOC(CC)C(=O)Nc1cc(OC)ccc1F +COc1ccc2c(c1)OCC(Cc1ncccc1C(=O)N(C)C)C2 +COc1ccc(C(=O)NCC2(c3ccccc3)CCOCC2)cc1F +CCN(c1ccc(C(=O)NC(C)C(C)n2cncn2)cc1)C(C)C +CC(C)Nc1cccc(C(=O)N(C)CC(=O)NCc2cccs2)c1 +CCCCC(=O)NC(C)c1cccc(N2CCCC2=O)c1 +CCCCn1c(C)c(C)c2c1ncn1nc(-c3ccccn3)nc21 +CC(=O)c1ccc(C(=O)N2CC=C(c3ccccc3)CC2)s1 +CCN(Cc1nccn1Cc1ccccc1C)C(=O)CC(C)C +COc1ccc(N(C)S(=O)(=O)c2ccc(Cl)cc2F)cn1 +CNc1nnc(SCC(=O)NC2CCCCC2)s1 +COc1ccc(C2=CCN(C(=O)c3ccc(C)nc3)CC2)cc1 +CNS(=O)(=O)c1ccc(C(C)NC(=O)c2cc(C)n[nH]2)cc1 +O=C(Cc1ccc(F)c(F)c1)Nc1ccn(CCc2ccncc2)n1 +CCCC(=O)N1CCC(C(=O)N(C)CCc2ccc(F)cc2)CC1 +O=C(c1cccnc1)N1CCN2C(=O)N(c3ccccc3)CC2C1 +COc1ccc2c(c1)c1ncnc(N(C)C)c1n2C +CC1CN(C(=O)c2cccc(Br)c2)C(C)CO1 +O=c1c(NCCc2ccncc2)nccn1C1CC1 +CC(C)Nc1ncc(-c2nccn2-c2ccc(F)c(F)c2F)cn1 +CC(C)N1CC(C2N=CC(c3ccccc3)=N2)CC1=O +O=C(Nc1ccc(-c2nnnn2C2CC2)cc1)OCC(F)(F)F +CCOc1ccccc1CNC(=O)c1ccc(N2CCOCC2)cc1 +Cc1ccc(C(=O)n2nc(C#N)c(C#N)c2N)cc1 +Cc1cc2c(cc1NC(=O)NCCCn1cncn1)OCCO2 +O=C(CCOc1cccc(F)c1)NC1CCCC1 +CCN(CCO)C(=O)C1CCCN(C(=O)c2ccc(Cl)cc2)C1 +CC(C)C(=O)Nc1ccc(C(=O)Nc2ccccc2F)cc1 +CC(NC(=O)CNS(=O)(=O)c1cn(C)cn1)c1ccccc1 +CC(C)CCNC(=O)Cn1nc2c(cc1=O)CCCC2 +CCC1N(S(=O)(=O)c2ccccc2F)CCCC12CCC(=O)N2 +COc1cc(OC)cc(C(=O)NC(C(=O)NC2CCCC2)C(C)C)c1 +COC(=O)c1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1 +CCNC(=O)NC1CCN(C(=O)c2ccc(F)cc2)C1 +Cc1cc(-c2nnc(CCC(=O)N3CCOCC3)o2)n(C)n1 +CN(CCOc1ccccc1F)C(=O)c1c[nH]c2ccc(F)cc12 +CC(Nc1nncc(-c2cccc3ccccc23)n1)c1cnn(C)c1 +CC(CNC(=O)c1ccccn1)CN1CCCC1=O +Cc1ccc2nc(NC(=O)Cc3c(C)nc(C)[nH]c3=O)sc2c1 +CC(NC(=O)Nc1nncs1)c1ccc2c(c1)CC(=O)N2 +Cc1c(C#N)nnn1CCCCOc1ccccc1 +CC(C)(C)C(=O)N1CCCC1C(=O)Nc1cccc(-c2ccn[nH]2)c1 +Cc1c(C(=O)NC2CCCOC2)nnn1-c1ccccc1 +COCC(=O)NCc1cc(OC)c(OC)c(OC)c1 +CCOC(=O)N1CCc2nc3ccccc3c(C)c2C1 +O=C(Oc1ccc(-c2noc(C3CC3)n2)cc1)C1CC=CC1 +CSc1ncnc(NCCc2cccc(Cl)c2)c1C#N +Cc1ccsc1-c1nn2c(-c3cnn(C)c3)nnc2s1 +CC(NC(=O)c1ccnc(-n2cncn2)c1)C(N)=O +CCc1nc2n(n1)CCCC2NC(=O)NCC(C)N1CCOCC1 +CCOCc1ccccc1NC(=O)N1CCc2sccc2C1 +CC1CN(CC(=O)Nc2sccc2C#N)CC(c2ccccc2)O1 +O=C(CCC(=O)c1ccccc1)Nc1ccc(N2CCNC2=O)cc1 +Cc1cc(C)nc(SCC(=O)NCc2cc(F)ccc2F)n1 +CC(=O)c1ccc(NCCC(O)c2ccc3c(c2)OCO3)cc1 +CCOc1cc(C)c(C(C)C)cc1S(=O)(=O)NCc1ccco1 +CCOc1ccc(C(=O)Cn2cccn2)cc1Cl +CC1CCCN(C(=O)CCc2c[nH]c3ccccc23)C1 +CC(C)c1cncnc1NC1CC(=O)N(CC2CCCCC2)C1 +Cc1nc(NCc2snnc2C)c2cccnc2n1 +CC1CN(C(C)(C)CNC(=O)c2cc(Cl)c[nH]2)CC(C)O1 +Cc1c(C(=O)NCc2ccc(-n3ccnc3)nc2)cnn1C +CC1CN(C(=O)c2cccc(Cl)c2Cl)CCC1(C)O +CC(C)C1Oc2cc(N)ccc2N(CCO)C1=O +CC(C)Cc1nc(Cn2cnc3c(cnn3C)c2=O)no1 +CNC(=O)CC(C#N)c1ccccc1Br +CCCOC(=O)CCC(=O)c1ccc(Cl)cc1 +COc1cc(CCNC(=O)Cn2ccc(=O)n(C)c2=O)ccc1C +COc1ccc(C(=O)Nc2cc(C)ccc2O)cc1 +COC(=O)c1cc(C)ccc1NC(=O)c1cccnc1 +CN(Cc1cccnc1)c1nc2c(s1)C(=O)CCC2 +Cc1ccc(SCCNC(=O)c2ccc3c(c2)CCC(=O)N3)cc1 +Cc1cc(C(=O)N(C)C(C2CC2)C2CC2)c2ccccc2n1 +CC(C)C(C(=O)Nc1ccc(F)c(C#N)c1)N1CCCC1=O +COc1ccc(OC)c(C(=O)Nc2ccc3c(c2)OCCO3)c1 +CC(C)CC(=O)N1CC(C)N(C(=O)CC(C)C)CC1C +Cc1ccc(CN(C)C(=O)c2cc(S(N)(=O)=O)c(C)o2)o1 +CCOc1ccccc1CNC(=O)Nc1cccc(NC(C)=O)c1C +NC(=O)c1cccc(CNc2ccc(F)cc2OCC2CC2)c1 +CSc1nc2nc(C)c(CC(=O)NC(C)C#N)c(C)n2n1 +CC1CCC(C(N)=O)CN1c1ncnc2ccsc12 +Cc1cccc(NC(=O)CCNC(=O)N(C)C(C)C)n1 +COc1ccc(S(=O)(=O)N(C)CC(=O)N2CCCCC2)cc1C +COc1cc(C(=O)N(C)C)ccc1OCc1ccc(Cl)cc1 +CN1CCC2(CCCN(S(=O)(=O)Cc3ccccc3)C2)C1=O +Cc1cc(F)ccc1NC(=O)c1c(C)cc(=O)oc1C +Cc1cc(NC(=O)c2ccc(-c3ccc4c(c3)OCCO4)s2)[nH]n1 +Cc1ccc(C)c(S(=O)(=O)NC(=O)C(C)O)c1 +Cc1csc2ncn(Cc3nccs3)c(=O)c12 +COc1cc(CNn2cnnc2)ccc1OCc1ccc(C)cc1 +CC1CN(c2ccccc2C#N)C(=O)CN1C(=O)c1cc(C2CC2)n[nH]1 +O=C(NCc1ccccc1)N1CCCC1c1nc(-c2cccnc2)n[nH]1 +CC(C)CCn1ccc2cc(NC(=O)c3ccn4nnnc4c3)ccc21 +CC(C)CN(CC(C)C)C(=O)c1ccc(=O)n(Cc2ccccc2)n1 +N#Cc1ccc(CN2CCSc3ccc(N)cc32)c(F)c1 +O=C(NCCNc1ncccn1)c1ccc(Br)cc1 +CCNC(=O)CSc1nc(Cc2ccccc2)c(C)[nH]1 +CCOC(=O)Nc1ccc(C)c(N2CCCCC2=O)c1 +CC(C)Cn1c(CC2(CC(=O)N(C)C)CCCC2)nc2cccnc21 +COc1nc(C2CCCO2)nc(NC2CCCC2)c1N +Cc1noc(C)c1CNC(=O)CC1NC(=O)c2ccccc2NC1=O +Cn1nc(CC(=O)N2CCOC3CCCCC32)c2ccccc2c1=O +CC(C)C(=O)Nc1cccc(NC(=O)c2ccc3c(c2)OCCO3)c1 +N#Cc1cccn(-c2ccc(Cl)cc2Cl)c1=O +O=C1CN(C(=O)CCc2ccc(Cl)cc2Cl)CCN1 +CCCS(=O)(=O)N1CCN(C)C(c2ccc(C)cc2)C1 +COC(=O)C1(NC(=O)c2ccc(N3CCC(O)CC3)cc2)CCCC1 +COc1cccc(CC(=O)NCC2(O)CCc3ccccc32)c1 +Cn1cc(C(=O)NCc2nnc3n2CCCCC3)c2ccccc21 +CCOC(=O)c1cc(-c2cc(C)ccc2O)nn1C +Cc1ccc(CS(=O)(=O)Nc2ccc3c(c2)CC(=O)N3)cc1 +COCCN1CC(CNC(=O)CC23CC4CC(CC(C4)C2)C3)CC1=O +Cc1sc(NC(=O)C2CCC(=O)N2)nc1-c1ccc(F)cc1 +Cc1cccc2c(=O)n(CC(=O)N(Cc3ccccc3)C3CC3)cnc12 +CCNC(=O)CNC(=O)c1cc(C)ccc1NCC +Cn1nnnc1SC(C)(C)C(=O)Nc1ccc(F)cc1 +Cn1cncc1C(=O)N1CC2OCCN(CC3CCCO3)C2C1 +COc1cccc(-c2cc(C(C)=O)c(=O)n(CC(C)C)n2)c1 +COc1ccc(NC(=O)CN2CCCCCC2=O)c(N)c1 +Cc1ccc(NCC(=O)Nc2c(C)cccc2C)cc1-n1cnnn1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1ccccc1F +COc1c(NC(=O)Nc2cnccc2C)c(C)nn1C +Nc1cccn2cc(-c3ccc(F)c(Cl)c3)nc12 +O=C(NCc1ccc2c(c1)OCO2)c1cc(-c2cccc(F)c2)no1 +Nc1cccc(C(=O)OCC(=O)c2cccnc2)c1 +Cc1ccc(C(=O)N2CCCN(c3cccnn3)CC2)s1 +Cc1ccc(Cc2nc(C(=O)N(C)c3c(C)noc3C)cs2)cc1 +CCn1c(-c2ccc(F)cc2)ccc(C(C)=O)c1=O +CC1(NC(=O)Nc2ccc(-n3cccn3)c(F)c2)CCOCC1 +Cc1cc(Cn2c(-c3ccccc3C)noc2=O)no1 +O=C(NCCO)c1ccc(COc2cccc(Br)c2)o1 +CC1CCCCC1NC(=O)CCn1c(=O)sc2ccccc21 +O=C(NCc1ccc(Cl)cc1)NCC1CN2CCCCC2CO1 +O=C(Nc1ccnn1Cc1cnn(-c2ccccc2)c1)c1ccccc1 +CN1CCN(S(=O)(=O)N2CCOCC2)Cc2ccccc21 +Cc1nn(C)c2ncc(NC(=O)NC3CCOc4ccccc43)cc12 +CC(C)c1cc(NC(=O)c2cccc(N(C)C)c2)[nH]n1 +Cc1ccc2ncc(C(=O)N3C(C)CCCC3C)n2c1 +COCCC(C)NC(=O)c1ccc2c(c1)OCCCO2 +Cc1cc(C(=O)N2CCOC(Cc3ccc(F)cc3)C2)c(C)o1 +CC1COCCN1C(=O)NCCCN(C)c1ccccc1F +CCNC(=O)CNC(=O)Nc1ccc2nc(C(C)C)sc2c1 +CN(Cc1ccco1)C(=O)C1COc2ccccc2O1 +O=C(NCCCOc1ccccc1F)c1cnc2ccccn2c1=O +O=C(C1CCC1)N1CCC(C(=O)N2CC(Oc3ccccc3)C2)CC1 +C#CCn1c(-c2cccc(N)c2)nc2cc(OCC)ccc21 +Cc1cc(C)n(C2CCCN(C(=O)CN3CCCS3(=O)=O)C2)n1 +Cc1cocc1-c1nc(N2CCCCC2)ncc1-c1cnccn1 +CN(CC(=O)c1c[nH]c2ccccc12)Cc1nc2ccccc2c(=O)[nH]1 +CCc1nc(COc2cccc(OC)c2)sc1C(C)=O +COc1cc(C#N)cc(Cl)c1OC(=O)CCNC(=O)c1ccco1 +O=S(=O)(CCNc1ncccn1)c1ccc(Br)cc1 +Cc1nn(C)c(NC(=O)Cc2c(F)cccc2F)c1C +CC(=O)c1cccc(NS(=O)(=O)c2ccc(-n3cccn3)cc2)c1 +CCCOc1cccc(CCNC(=O)Nc2cnccc2C)c1 +O=S(=O)(NCCCn1cccn1)c1cccc(C(F)(F)F)c1 +Cc1ccccc1C(CC(=O)NC1CCC(O)CC1)NC(N)=O +COc1cccc(N2CCN(c3nc(C(=O)N(C)C)cs3)CC2)c1 +Cc1cc(-c2nc3c(CO)cccn3c2N)ccc1Cl +Cc1[nH]c(=O)c(C(=O)NCCN2CCOCC2)c(C)c1N +COc1ncccc1C(=O)NCCN1CCN(C(C)=O)CC1 +N#Cc1cc(-c2ccc3[nH]c(=O)oc3c2)n(CCO)n1 +Cc1ccnc(NC(=O)COC(=O)c2ccc3ncsc3c2)n1 +Cc1nc(CN2CCOC3CN(Cc4ccoc4)CC32)cs1 +Cc1cc(NC(=O)CCCn2cncn2)ccc1Oc1cccnc1 +COC(=O)c1c(C)[nH]c(C(=O)C(C)Sc2nncn2C)c1C +CN(CC(=O)OCC1COC(C)(C)O1)Cc1ccccc1 +COc1ccc(-c2nc3ccc(C)cn3c2CC#N)cc1OC +Cc1csc(Sc2ccc(Cl)cc2N)n1 +COc1cc(C)ccc1OCc1nc(C(=O)NC2CCCC2)co1 +CC(Cn1cncn1)NC(=O)Nc1cccc(-c2cccs2)c1 +CCCCOCCNC(=O)Nc1ccc(C#N)c(Cl)c1 +CC(=O)NCCC1CCCCN1C(=O)c1nn(C)c(C)c1Cl +CCCc1c2c(nc3cc(C(N)=O)n(C)c13)CCCC2=O +COc1ccc2c(c1OC)C(C(=O)N(C)C)CC2=O +COc1cc(OC)cc(C(=O)Nc2cc(C)ccc2OC(C)=O)c1 +CC(=O)c1cc(-c2ccncc2)nn1Cc1ccccc1 +CCOc1ccc(NC(=O)c2cnn3c(=O)c4c([nH]c23)CCC4)cc1 +CCN(CC(=O)OC)S(=O)(=O)c1cc(F)ccc1C +COc1cc(CNC(=O)c2ccc(Cl)cn2)cc(OC)c1O +O=C(NCCNc1ncnc2c1oc1ccccc12)c1cccnc1 +N#CC1(C(=O)NCc2ccccc2CN2CCCC2=O)CCCC1 +CC(C)c1ncc(Cl)c(C(=O)NC(C)C2CCCO2)n1 +COCC1CN(Cc2ccc(C)o2)Cc2nnn(C)c21 +Cc1ccc(C(=O)Nc2cc(S(C)(=O)=O)ccc2Cl)cn1 +Cc1ccc(C(=O)NCCNc2ncccn2)cn1 +N#CCCC(C#N)CSc1nc(C2CC2)n(-c2ccccc2)n1 +Cc1n[nH]c(C)c1CCn1cnc(-c2ccccc2)c1-c1ccco1 +CCn1cc2c3c(cccc31)CN(C(=O)c1ccccc1F)CC2 +COCCOc1ccc(CNS(C)(=O)=O)cc1 +Cc1cccc(C(=O)NCCNC(=O)C(O)c2ccccc2)c1 +CCCNC(=O)c1cccc(C(=O)N=c2[nH]nc3cc(C)ccn23)c1 +CCOc1ccccc1NC(=O)CSc1ccc(NC(C)=O)cc1 +Cc1ccc(Cl)c2c1CCNC2C(O)C(C)C +CNc1nc(-c2sc(N3CCCCCC3)nc2C)cs1 +COc1ccc(NC(=O)NCc2cccs2)c2cccnc12 +CC(C)(C)OC(=O)NCC(=O)Nc1ccc(F)c(C#N)c1 +CC(=O)Nc1cccc(C(=O)NCc2cccc3ccccc23)c1 +CCc1nnc2c(NCC3CCCO3)nc3ccccc3n12 +CCc1oc(C(=O)N(CCC#N)c2ccc3c(c2)OCCO3)cc1C +CCC(C)NC(=O)c1cc(C)c2c(=O)n(C)c(=O)n(C)c2n1 +O=C(Cc1csc(Nc2ccc(Cl)cn2)n1)NCc1ccco1 +CCN(Cc1ccccc1C)CC(O)CN1CC(C)OC(C)C1 +CCOc1cc(C#N)ccc1OC(=O)c1ccsc1 +O=C(CCCc1c[nH]c2ccccc12)Nc1ccc2c(c1)OCC(=O)N2 +Nc1oc(-c2ccccn2)cc1C(=O)c1ccncc1 +CC1CCN(C(=O)c2cc(F)ccc2NC(=O)C2CC2C)CC1 +Cc1c(-c2cc(=O)[nH]c(=O)[nH]2)c2ccccc2n1C +CC1(NC(=O)NCc2ccccc2-n2ccnc2)Cc2ccccc2C1 +O=C(Nc1ccccc1Cl)N1CCC2(CC1)OCCCO2 +Cc1cc(C)cc(NC(=O)CCc2cccc(N)c2)c1 +Brc1ccn2nc(-c3ncsn3)ncc12 +Cc1ccc(C(=O)NC(C)COc2ccccc2C)o1 +CC(C)(NC(=O)Cn1ccccc1=O)c1ccccc1 +Cc1ccc(CC(=O)Nc2ccc3oc(=O)[nH]c3c2)cn1 +COc1ccc(C(C)OC(=O)CCC2CCCO2)cc1F +Cc1cc(NC(C)c2csc(C)n2)n2nc(C)c(C)c2n1 +CCn1cc(S(=O)Nc2ccc(S(C)=O)c(F)c2)cn1 +CCNc1ncc(C(=O)NC(C)c2ccc3c(c2)CCCC3)cn1 +CC(Nc1ncc(C(F)(F)F)cc1Cl)C1CCCO1 +COC(=O)Cn1nc(C)c2c(C(F)F)cc(-c3cn(C)nc3C)nc21 +COc1cc(CN2CCC3(C2)OCCO3)cc(OC)c1 +c1ccc2c(SCc3noc(C4CC4)n3)nc(C3CC3)nc2c1 +CC(=O)Nc1ccccc1CNc1cnn(CC(C)C)c1 +Cn1c(CN2CCCCC2C2OCCO2)cc(=O)n(C)c1=O +COc1ccc(NC(=O)N2CCC(CO)CC2)cc1C +Cn1ccnc1SCC(=O)Nc1ccc(Cl)c(N)c1 +COC(=O)Cc1ccc(OS(=O)(=O)c2ccc(F)cc2F)cc1 +CC(=O)Nc1ccc(NC(=O)NCc2ccc(C)cc2N(C)C)cc1 +CCN(CC)S(=O)(=O)N1CCC(NC(=O)C2CCCCC2)CC1 +CN(Cc1ccncc1)C(=O)CCCc1cccs1 +CCS(=O)(=O)NCc1ccccc1-n1cccn1 +COc1ccc(C(C#N)CC(=O)NCc2ccncc2)cc1 +O=C(c1cccnc1)N1CCCC(Cc2nccs2)C1 +CSc1nc(C)c(CCC(=O)NCC2CCC2)c(C)n1 +Cc1cc(Cl)ccc1N(CC(=O)N(C)C)S(C)(=O)=O +CC(C)C1C(=O)NCCN1Cc1cnc(C2CCC2)s1 +Cc1cc(C)n2nc(SCCc3cccs3)nc2n1 +Cc1ccc(C)c(-n2nnnc2SCC(=O)Nc2nccs2)c1 +C#CCNC(=O)C1CC(=O)N(c2cccc(Br)c2)C1 +O=C(Cc1c[nH]c2ccccc12)NCC1COC2(CCCCC2)O1 +Cc1cccc(OC(C)(C)C(=O)N2CCNCC2)c1C +COc1cc(CNC(=O)N(Cc2ccco2)Cc2ccco2)ccn1 +CCC(CC)NC(=O)c1ccc(-c2ccco2)[nH]c1=O +CCn1nc(C)c(CCNC(=O)Nc2ccccc2F)c1C +CC(=O)N(CCc1ccccc1)CC(=O)N1CCOC2(CCCC2)C1 +O=C(NCc1ccccc1F)Nc1nnc(-c2ccsc2)s1 +CC(C)OCCC(=O)Nc1ccc(C(=O)NC2CC2)cc1 +Nc1[nH]nc(-c2ccncc2)c1-c1cccc(F)c1 +Cc1ccc(-c2nnc(CNC(=O)CC3CCCC3)o2)cn1 +CCOC(=O)N1CCN(c2cnn(C)c(=O)c2Cl)CC1 +CC(C)(C)c1nnc(Sc2ccc3nnc(C(F)(F)F)n3n2)o1 +CC(=O)N1CCC(C(=O)OCCn2c(=O)oc3ccccc32)CC1 +CSc1ccc(NC(=O)c2ccc(S(N)(=O)=O)cc2)cc1 +CCS(=O)(=O)N1CCN(S(=O)(=O)C2CC2)CC1 +CCC(C)CNS(=O)(=O)c1cccc(C#CCO)c1 +COC(=O)c1ccoc1CN1CCCCCC1c1ccco1 +O=C(NCCc1cccs1)NC(CO)Cc1c[nH]c2ccccc12 +Cc1cccc(N(CCC(N)=O)C(=O)c2cccc(CC#N)c2)c1 +CC(C(=O)NC1CCCC1)N1CCN(C(=O)c2ccccc2)CC1 +Cc1ccc(-n2nnnc2SCC(=O)N2CCCCC2C)cc1C +Nc1cc(=O)[nH]c(=O)n1-c1ccc(OC(F)F)cc1 +CCC(=O)N1CCCC(C(=O)N2CCC3(CCCCC3)C2)C1 +Cn1cc(C(=O)N2CCCN(CC(F)(F)F)CC2)cn1 +Cc1cc(CC(C)NC(=O)c2ccc3c(c2)CCO3)[nH]n1 +O=C(Cn1cccn1)NCC1Cc2ccccc2O1 +CCC(C)NC(=O)NC(CC)c1ccc(Br)cc1 +O=C(Nc1ccccn1)N1CCc2cc(Br)ccc21 +CC(=O)Nc1ccc(NC(=O)C2CC3CCC2O3)c(Cl)c1 +CCCC(=O)Nc1cccc(C(=O)Nc2ccc(OC)cc2OC)c1 +NC(=O)Nc1cccc(OCC(=O)N2CCCC2)c1 +Cc1ccc(-c2cc(-c3ccc(Cl)cc3)nc(N)n2)o1 +CN1C(=O)COc2cc(-c3noc(C(=O)NC4CCCC4)n3)ccc21 +CCOC1CCCN(C(=O)NCCC(=O)N(C)Cc2ccccc2)C1 +CCCCOC(=O)c1ccc(NC(=O)N2CCOCC2)cc1 +O=C(c1ccc[nH]1)N1CCC2OC(COCC3CCOCC3)CCC21 +N#Cc1ccc(CNCCc2cc(F)cc3c2OCOC3)cc1 +CCC(=O)Nc1ccc(CN2CCOCC2)c(Cl)c1 +O=c1c2ccccc2nc(SCCCCO)n1CC1CCCO1 +Nc1ccccc1OCCCCn1nnc2ccccc21 +Cn1cc(C(=O)NC2CCCCC2Cc2ccccc2)ccc1=O +CCc1nn(C)c(CC)c1S(=O)(=O)Nc1ccnn1CC(C)C +COc1cc(C(=O)NCc2cccs2)cc(OC)c1OC +CC1CC(=O)N(C)c2ccccc2N1S(=O)(=O)c1cccc(F)c1 +CCCCNC(=O)C1CCCN(Cc2nc(C)cs2)C1 +O=C(NC(Cc1ccccc1)C(=O)NC1CC1)c1cnc2[nH]ccc2c1 +Cn1cc(-c2nc(C(=O)N3CCc4cc(F)ccc4C3)cs2)cn1 +Cc1nc(-c2ccsc2)sc1C(=O)NCCNC(=O)C(C)C +Cc1cccnc1NC(=O)c1cc(C2CC2)nc2c1c(C)nn2C +CC(=O)c1c(F)cccc1NCC1CCN(CC(F)(F)F)C1 +Cc1ccc(Cn2nnc(-c3cccnc3)n2)cc1 +CCC(=O)Nc1cccc(C(=O)N(C)C(C)c2sc(C)nc2C)c1 +CCSc1ccc(NC(=O)N2CC(C)OC(C)C2)cn1 +CC1CN(c2ccccc2NC(=O)COCC2CC2)CC(C)O1 +CN(C)C(=O)CN(C)C(=O)c1ccc(Cl)cc1Cl +Nc1nccnc1C(=O)NCc1ccccc1CN1CCCC1=O +O=C(Cc1csc(-c2ccccc2)n1)NCC1CCCO1 +CC(=O)NC1CN(C(=O)c2cnn3c2CCCC3)CC1C(C)C +CCc1n[nH]c(C2CCCN(C(=O)Cc3c[nH]c4ccccc34)C2)n1 +Cc1ccc(NC2c3ncccc3C(=O)N2Cc2ccco2)c(C)c1 +COc1ccc(OCc2nc(CCO)c(C)o2)cc1 +CC(C)c1ccc(CCC(=O)N(C)C2CCN(C)C2=O)cc1 +COC(=O)c1ccc(N2CCN(c3ccccc3)CC2)nc1 +Cc1ccc(-c2cc(C(=O)NCc3cc(F)ccc3F)[nH]n2)s1 +NC(=O)c1cccc(CNC(=O)Nc2ccc(Cl)cc2F)c1 +CC(=O)NC(CC(=O)OCC1CCC(=O)N1)c1ccc(Cl)cc1 +CCCn1c(SCC(=O)N2CCCCC2C)n[nH]c1=O +C=CCOc1cccc(-c2nc(-c3ccncc3)no2)c1 +CC(CCNC(=O)c1ccsc1)N(C)C(=O)OC(C)(C)C +N#Cc1cc(F)ccc1NC(=O)N1CCN(c2ccc(F)cc2)CC1 +Cc1ccc(-c2ccc(=O)n(CC(=O)Nc3cccc(F)c3)n2)s1 +Cn1cccc1C(=O)N1CC(n2cc(-c3ccccc3)nn2)C1 +Cc1cccc(NC(=O)C(O)c2ccc(Cl)cc2)c1 +Cc1ocnc1CNC(=O)Nc1ccc(NC(=O)c2ccco2)cc1 +CCCC(=O)Nc1cc(Cl)ccc1-n1cncn1 +Cc1cccc(OC(=O)C2CCCN2S(=O)(=O)c2ccccc2)c1 +N#Cc1ccc(-c2nc(-c3ccc4nncn4c3)no2)cc1 +CN(CC(=O)NCc1ccc(F)c(Cl)c1)c1ccc(C#N)cn1 +COc1ccc(OC)c(Nc2nc(CC(=O)NC(C)C)cs2)c1 +CCC1COCCN1C(=O)c1cc(N2CCCC2=O)ccc1Cl +COc1cc(C#N)ccc1OC(C)C(=O)Nc1c(C)nn(C)c1C +CC(C)CNC(=O)C(C)Sc1ccc(C(F)(F)F)cn1 +Cc1cnn(CCC(=O)NCc2cccc(C(F)(F)F)c2)c1 +O=C(CN1CCN(C(=O)c2ccccc2O)CC1)N1CCCCCC1 +CC(C)C(=O)NCCN(C)C(=O)Cc1cccc(O)c1 +COc1cc(CNC(=O)c2cnn(Cc3ccccc3)c2)ccn1 +O=C(c1ccno1)N1CCn2c(cc3ccccc32)C1 +CN(c1ccccn1)S(=O)(=O)c1ccc(F)c(C(F)(F)F)c1 +CC(C)C(=O)Nc1ccc(Cl)c(C(=O)NC2CCCOC2)c1 +CC(=O)Nc1ccc(SCC(=O)NCCc2ccccn2)cc1 +Cc1csc(N(C)C(=O)Cc2csc(N3CCNC3=O)n2)n1 +Cc1ccn2c(=O)c(C(=O)NC(C)c3ccc(F)cc3F)cnc2c1 +CNS(=O)(=O)c1ccc(C(C)NC(=O)N(C)CCC(C)C)cc1 +O=C(Cn1nc(C(=O)N2CCCC2)ccc1=O)Nc1ccccc1F +O=C(c1ccccc1O)N1CCOC(c2ccccc2)C1 +Cc1cc(NC(=O)CCc2ncc(-c3ccc(F)cc3F)o2)n(C)n1 +Cc1cc(C2CCCN2C(=O)c2cnc(C(C)(C)C)s2)no1 +NC(=O)C1CCN(C(=O)c2cccc(Oc3ccccc3)c2)C1 +CCc1sc(C(=O)N2CCn3cccc3C2C)cc1C +Clc1ccc2c(c1)C(N1CCOCC1)CCN2 +COc1cccc(-c2cc(C(=O)Nc3cccc(F)c3)n[nH]2)c1 +O=C(c1ccccc1)N1CCC(Nc2ncccn2)CC1 +CCCC1CN(C(=O)C2CCCN(C(=O)OC)C2)CCO1 +CC(CNC(=O)NCc1cccnc1)Cn1cccn1 +COC(=O)CCNC(=O)Cc1ccc(F)c(Br)c1 +CC(C)CC(NC(N)=O)C(=O)NCc1ccc(C(C)(C)C)cc1 +COc1cc(CNc2ccccc2C)cc(OC)c1OC +Cc1ccc(OCCN2C3=NC(=O)CN3c3ccccc32)cc1 +Cc1ccc(NC(=O)CSc2nc3ccc(N)cc3s2)cc1F +CC(=O)N1CCN(C(=O)c2c(C)nn3ccccc23)CC1 +COc1ccc(CCn2cc(-c3nc(C)no3)ccc2=O)cc1 +Cc1noc(COC(=O)c2c(C)nn(Cc3ccccc3)c2C)n1 +O=C(NC1CC2CCC1C2)c1cccc(S(=O)(=O)N2CCCC2)c1 +CN1C(=O)CN(C(=O)CCSc2ccccn2)c2ccccc21 +Nc1c(Br)cccc1C(=O)OCC1CCOC1 +CC(C)NC(=O)Cn1c(=O)c(C#N)cn(C2CC2)c1=O +Cc1ccncc1NC(=O)NCc1ccc(F)c(Cl)c1 +COc1ccc(C(=O)Nc2nc3c(OC)ccc(OC)c3s2)cc1 +NC(=O)c1ccccc1NC(=O)Nc1c[nH]c2ccccc12 +COc1ccc(N)c(NC(=O)C2CC3CCC2C3)c1 +CCOC(=O)N1CCN(c2c(OCC)c(=O)c2=O)CC1 +COC(C)C(=O)NCCNc1ncc(Cl)cc1Cl +O=S(=O)(NCc1cn2cc(Cl)ccc2n1)c1cn[nH]c1 +Cc1cc(N)cc(-c2nc3cccc(C)c3o2)c1O +Cc1ccc(CNC(=O)c2ccccc2Cl)n1C +COC(=O)Nc1nc2c(s1)CN(C(=O)c1cc(C)cc(C)c1)CC2 +CC(CC(O)c1ccccc1)NC(=O)Cc1ccc(F)cc1 +O=C(c1sccc1-n1cnnn1)N1CCC2(CCCCC2)CC1 +Cc1cc(C(=O)NC2CCSc3ccc(Cl)cc32)c(C)s1 +N#CCOc1ccc(NC(=O)c2cncn2-c2ccc(F)cc2)cc1 +CCC(C)NC(=O)c1c(C)nn(-c2ccc(F)cc2)c1C +Cc1noc(C2CC3CN(C(=O)c4ccc5c(c4)OCO5)CC3O2)n1 +Cc1cccc(NC(=O)c2ccc3c(c2)[nH]c(=O)c2ccncc23)c1 +CC(C)(C)c1nc(Cn2cccc(C(F)(F)F)c2=O)no1 +Cc1nn2cccnc2c1C(=O)OCCc1cccs1 +Cc1c(C(=O)NCc2ccccc2Cl)sc2nc[nH]c(=O)c12 +COC(=O)CNC(=O)c1cccc(OCC(F)F)n1 +O=c1ccccn1CCCCOc1cccc(C(F)(F)F)c1 +Cc1cccc(=NS(=O)(=O)c2sc(C)nc2C)[nH]1 +CC(C)(C)OC(=O)N1CCCC(C(=O)NCC2CC2)C1 +CSc1nnc(CNC(=O)Nc2ccccc2C(F)(F)F)n1C +Cc1cc(=O)[nH]c2ccc(S(=O)(=O)N3CCC(C)CC3)cc12 +O=C(Cc1cccs1)N1CCC(Cn2cnc3ccccc32)CC1 +COc1ccccc1C(=O)N1CCOC(c2ccc(F)cc2)C1 +CN(CCC#N)C(=O)CNc1cc(F)cc(Br)c1 +Cc1ccc(OCc2nnc(SCC(N)=O)n2C)cc1 +Cc1ccc(C(=O)N2CCOCC2)cc1NC(=O)C1CC2CCC1C2 +Cc1ccc(CNC(=O)C2c3ccccc3CC(=O)N2C(C)C)cc1 +CC(C)NCC(=O)OCc1ccc2c(c1)CC(=O)N2 +CCCCC(=O)N(CC)CC1COc2ccccc2O1 +COc1cccc(-c2n[nH]c(-c3ccc(O)c(OC)c3)n2)c1 +CCC(CO)NC(=O)NCc1ccc(OC)nc1 +O=C(Cc1noc2ccccc12)N1CCCCCC1c1ccncc1 +Cc1nc2scc(C)n2c1CNCc1cccnc1 +COc1ccc(NC(=O)Cc2ccc(F)cc2)c(N)c1 +CCS(=O)(=O)N(C)C1CCN(C(=O)OC(C)(C)C)CC1 +O=C(Cc1c[nH]c2ccccc12)Nc1cnn(-c2ccccc2F)c1 +Nc1ccc2c(c1)CCN2C(=O)COc1ccccc1Cl +CCCCn1nccc1NC(=O)CSc1ccccc1 +CCCn1ccnc1-c1cn(Cc2cc(C(C)(C)C)n[nH]2)nn1 +CN(CC1CC1)c1ccc(S(C)(=O)=O)cc1S(C)(=O)=O +c1cncc(-c2nnc(NCC3CCCO3)s2)c1 +CSc1cc(C(=O)Nc2ccc3nc(C)oc3c2)ccn1 +COc1cccc(-n2nnc(CO)c2CC(C)C)c1 +Cc1ccc(N)cc1N1CCN(C(=O)C2CCC2)CC1 +CCOC(=O)CN(CC)C(=O)Cc1c(C)nn(C)c1C +O=C1Cn2nc(C=Cc3ccccc3O)nc2-c2ccccc2N1 +COc1cccc(N2CCCC(NC(=O)Cc3ccc[nH]3)C2=O)c1 +COc1ccc(-c2cc(=O)[nH]c(Nc3ccc(F)cn3)n2)cc1 +Cc1ccc(C2COCCN2C(=O)C2CC2c2cccnc2)o1 +O=c1cc(CN2CCN(CC3CC3)c3ccccc32)occ1O +CC(C)(CNC(=O)Cn1cnc2ccccc2c1=O)c1ccncc1 +CS(=O)(=O)Nc1cc(NC(=O)c2cccc(Cl)c2)ccc1F +c1cncc(OCc2cncc3c2CCN(Cc2ccoc2)C3)c1 +O=C(Nc1cccc(Cl)c1F)c1ccnc(OC2CCC2)c1 +Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)c1ccoc1 +CC(C)c1noc(CCC(=O)Oc2ccccc2Br)n1 +Cc1ccc(NC(=O)N(C)Cc2cccnc2)cc1C +CCc1nc2n(n1)CCCC2NC(=O)CNC(=O)C1CCCC1 +C=CCN(Cc1cccnc1)Cc1ccc(C)s1 +Cc1cccc(S(=O)(=O)N(CCO)Cc2ccco2)c1 +CC1(NC(=O)CCc2ccc(C#N)cc2)CCCC1 +O=C(NCc1ccco1)N1CC=C(c2ccccc2)CC1 +CC12CCC(C(=O)N3CCc4ccccc4C3)(CC1=O)C2(C)C +O=C(Nc1cccnc1)C1CCCN(C(=O)c2ccc(F)cc2)C1 +Cc1nc(-c2cccs2)sc1C(=O)NCCS(N)(=O)=O +CNC(=O)c1ccc(NCc2cccc(C(F)(F)F)c2)nn1 +CCOC(=O)N1CCCC(C(=O)Nc2ccc3c(c2)CCC3)C1 +Cc1nc(C(=O)Nc2ccc3c(c2)OCO3)cs1 +O=C(NCC(O)CO)Nc1cccc(-c2c(F)cccc2F)c1 +Cc1ccc(NC(=O)C2CC2)cc1NCC(=O)N1CCOC(C)C1 +CCn1ncc(S(=O)(=O)Nc2ccc(C(N)=O)cc2)c1C +C=CCOc1cc(C(=O)NCc2cnn(C)c2C)cc2occc12 +CCOC(=O)c1nccn1CC(=O)Nc1ccc(C(C)C)cc1 +CCc1noc(CC)c1CC(=O)N(C)c1cccc2ncccc12 +CN(C(=O)CC1OCCc2ccccc21)c1ccc(Cl)cn1 +COc1ccccc1OCC(=O)Nc1ccc(F)c(F)c1 +CNS(=O)(=O)c1ccc(C(=O)N(C)CCCOC)cc1 +COc1ccc(CSc2nnc(-c3ccccn3)n2C)cc1 +O=C(COc1ccc(-n2cccn2)nn1)NCc1ccc(F)cc1 +CCc1nnc2c(N3CCCC3)nc3ccccc3n12 +CN(C)C(=O)CN(C(=O)c1scnc1C1CC1)c1ccccc1 +O=C(COc1cccn(CCO)c1=O)NCc1ccco1 +CCn1nnc2cc(C(=O)Nc3ncccc3C)ccc21 +COC(=O)NCC1CC(=O)N(c2ccc(OC)cc2)C1 +CCC(=O)Nc1nc2cc3c(cc2s1)OCO3 +CN1C(=O)C2(CCN(C(=O)c3ccnnc3)CC2)c2ccccc21 +Cc1cc(C(=O)N2CCN(CC(O)c3ccccc3)CC2)on1 +COc1ccc(O)cc1OCCNC(=O)OC(C)(C)C +Cc1nccn1-c1cccc(C2CCCN(S(C)(=O)=O)C2)n1 +COc1ccc(C(=O)NCCc2nccs2)cc1OC +Cc1ccccc1C(C)NC(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +CC(C)c1nn2c(CO)c(C(C)(C)C)nc2s1 +O=C(CCSc1ccccn1)NC1CCCN(c2ccccc2)C1 +COc1cc(C)ccc1OCc1cc(C(=O)NC2CCOCC2)no1 +CS(=O)c1ccc(CN2CCOC(c3ccccc3F)C2)cc1 +CC(C)CNC(=O)c1cc2occ(-c3cccnc3)c2[nH]1 +CN(C)C(=O)c1ccc(CNC(=O)C2CCCCC2)cc1 +O=C(NCc1cccc(F)c1)c1ccc(-c2cncnc2)nc1 +CCOC(=O)C(C)NC(=O)c1ccc(COC)cc1 +O=C(NCC1OCCc2ccccc21)C1(c2ccc(F)cc2)CC1 +CCCn1c(=O)c2c(nc3n(CC)c(C)cn23)n(C)c1=O +Cc1csc(=O)n1CC(=O)OCCCc1cccnc1 +COc1ccc(C)cc1NC(=O)COc1ccc(C(N)=O)cc1 +Cc1cc(C(=O)N2CCOC(c3cccc(OC(F)F)c3)C2)no1 +COc1cccc(C(=O)NCC(C)(C)c2ccncc2)c1O +CN(C(=O)c1cnccn1)C1CCc2ccccc2C1 +c1cnc(SCCOc2ccc3c(c2)CCC3)nc1 +O=C(COc1c(Cl)cc(Cl)cc1Cl)NCC1CCCO1 +NC(=O)CC1CCN(C(=O)C2(c3ccc(F)cc3)CCCCC2)CC1 +COC(=O)CSc1ncnc2ccc(Br)cc12 +CCCCS(=O)(=O)N(C)C(=O)c1cscc1C +Cn1c(=NC(=O)c2ccc(CNC(N)=O)cc2)sc2ccccc21 +O=C(c1ccncc1)N1CCN(Cc2ccc3c(c2)CCO3)CC1 +O=C(Nc1cccc(Oc2cnccn2)c1)c1ccc(F)c(F)c1 +COc1cc(NC(=O)C(C)OC)c(C(N)=O)cc1OC +COc1ccccc1C(NC(=O)CCC(C)C)c1noc(C)n1 +C#CCOc1ccc(C(=O)Nc2ccccc2C(=O)OC)cc1 +Oc1ccc2c(c1)OCC2Nc1ccc(F)c(F)c1F +O=C(COC(=O)c1ccccc1C(=O)c1cccs1)C1=NC=CC1 +Nc1ncnc(Oc2ccc3ccccc3c2)c1N +COc1ccc(-c2noc(Cc3cccc(OCC#N)c3)n2)cn1 +CN(CC(=O)NC(C)(C)C)C(=O)CSc1ncccn1 +O=C(CN1CCOc2ccc(Cl)cc21)Nc1ccc2c(c1)COC2 +O=C(Nc1cccn2ncnc12)c1cccc(C(F)(F)F)c1 +CCOC(=O)CN(Cc1ccc(C)s1)C1CC1 +O=C(CCCc1c[nH]c2ccccc12)NC1CCOc2ccccc21 +Cc1ccc(Cl)cc1NC(=O)N1CCN(C)c2ncccc21 +O=C(Oc1ccc2ccccc2c1)c1cnns1 +O=C1Nc2cc(F)ccc2C12CC(O)=Nc1[nH]ncc12 +CC1CCCN(C(=O)C2CCN(C(=O)c3ccco3)CC2)C1 +Oc1cc2c(cc1F)CCNC2Cc1noc2ccccc12 +NC(=O)C1CCN(C(=O)c2cccc(-n3cccc3)c2)CC1 +COC1COC2(CCCN(Cc3ccc(C)s3)C2)C1 +CCOc1ccccc1C(=O)NCC(=O)N1CCc2sccc2C1 +CC(C)(C)OC(=O)N1CCCC(C(=O)NCCc2cccs2)C1 +CC(C)C(=O)c1cn(CC(=O)NCc2cccs2)c2ccccc12 +Cc1ccc(-n2nc(C)cc2NC(=O)CN2CCOC(C)C2)cc1 +C#CCN1CCN(C(=O)NC(C)C(OC)c2ccc(Cl)cc2)CC1 +CCOc1ccccc1-c1cc(C#N)nn1CCO +CC(CN(C)C(=O)c1ccccc1-c1ncc[nH]1)N1CCOCC1 +CC(C)(CO)NS(=O)(=O)CCCc1ccccc1 +CSc1nnc(NC(=O)CSc2nc(C)c(C)o2)s1 +Cc1ccc(Cl)c(OC(=O)Cn2c(C)c(C)sc2=O)c1 +Cc1ccc(OC(C)C(=O)N2CCN(C(=O)c3ccco3)CC2)cc1 +CCCCN(CCO)C(=O)c1ccc(Cl)c(N)c1 +Cc1nnc(NC(=O)c2nn(-c3ccccc3)ccc2=O)s1 +COC(=O)C1=C(C)C(C(=O)Nc2cc(C)ccn2)=NC1C +Cc1nc(C)c(C(=O)Nc2nc3c(F)cc(F)cc3s2)o1 +Cc1ccccc1OCc1nn2c(=O)c(C)nnc2s1 +CC1CCCN1C(=O)CCn1nc(C2CC2)cc(C(F)(F)F)c1=O +NC(=O)CSc1nnc(-c2ccccc2F)o1 +COc1ccc(C(C)N(C)C(=O)c2ccco2)cc1 +Cc1ccc2c(c1)N(C(=O)CCC(=O)N1CCOCC1)CCO2 +Cc1cc(C(=O)COc2ccccc2C(N)=O)c(C)[nH]1 +O=C(Nc1ccc(Cl)cn1)c1ccc(Cl)cc1 +CCOCc1ccccc1NC(=O)Nc1ccn(C)n1 +CCOCCNC(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1C +CCOC(=O)c1coc(C(=O)Nc2ccc(F)cc2)n1 +CCOC(=O)C(C)Oc1ccc2ccc(=O)oc2c1 +CC1CC1COC(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1 +COCC(C)NS(=O)(=O)c1ccc(C)c(C)c1 +O=C(Cc1ccc(F)cc1)NCC1(O)CCOCC1 +Cn1ccnc1S(=O)(=O)CC(=O)NCC(F)(F)F +O=C(NCC1CCCO1)c1ccc(-c2cccs2)nc1 +Cc1ccc(C)c(OCCC(=O)NCc2cccnc2)c1 +CCC(CC)C(=O)Nc1cc(-c2cn3cccnc3n2)ccc1OC +CNC(=O)c1cc(NC(=O)NCc2cccc(C(N)=O)c2)ccc1F +Cn1nc2n(c1=O)CCN(CCC(=O)N1CCCCC1)C2 +Cc1cc(-c2ncc3c(Br)ccn3n2)ccn1 +Cc1cnc(C(=O)NC(c2ncccc2C)C(C)C)cn1 +CN(CCSc1ccccc1F)Cc1nccn1C(F)F +Cc1cc(C)cc(C(C)NC(=O)c2c(C)c(C)nn(C)c2=O)c1 +CC(NC(=O)Cc1ccc(Br)c(F)c1)C(N)=O +CCNC(=O)NCCOc1cccc(Br)c1 +COc1ccc(C(O)CCN2CC(C)OC(C)C2)cc1 +CCCNS(=O)(=O)c1ccc(OC)c(-c2nc(C)no2)c1 +O=C(c1cccc(Cl)c1)N1CCC2(CCCN(CC3CC3)C2=O)C1 +CCn1c(CC2CCN(C(=O)c3c[nH]c(=O)cn3)CC2)nn(C)c1=O +Cn1nc2nc(NC3CCCC3)nc(-c3ccccc3F)c2c1N +CC(C)(C)C(=O)NCCC(=O)NC1CC1c1cccc(Cl)c1 +Cc1c(NC(=O)c2ccncc2)cccc1S(=O)(=O)NC(C)(C)C +O=C(CCNC(=O)N1CCOCC1)N1CCCCC1 +N#Cc1ccc(-n2sc3ccccc3c2=O)nc1 +Cc1nncn1-c1cccc(NC(=O)Cc2ccc(F)cc2)c1 +O=C(NCc1noc(-c2ccsc2)n1)C1CCCC1 +CC(C)NC(=O)Cn1nc(-c2cccs2)n(-c2ccncc2)c1=O +COc1cccc(OCc2cc(C(=O)NCCO)n[nH]2)c1 +Cc1ccc(F)c(S(=O)(=O)N2CCc3sccc3C2)c1 +CC(C)(C)C(NC(=O)c1cc(F)cc(Br)c1)C(N)=O +Cc1ccc(CNC(=O)C2(CC(=O)NC(C)C)CCCC2)cc1 +CC(=O)c1ccc(NC(=O)CSc2nncn2C)cc1 +CNC(=O)CSc1nnc(-c2cccnc2)n1-c1ccc(C)cc1 +Cc1sc2nc(SCCOCCO)nc(N)c2c1C +CCCC(=O)NCC(=O)NC(C)c1ccc(-n2ccnc2C)cc1 +CCc1cc(OC(=O)Cc2nc3nc(C)cc(C)n3n2)ccc1Cl +CCn1nnnc1NCc1ccc(-c2ccccc2F)o1 +COc1ccc(-n2c3nc(=O)[nH]c(=O)c-3cc3c(F)cccc32)cc1 +CCc1ccc2c(Cn3cnc(C#N)n3)cc(=O)oc2c1 +CC(CO)NC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1 +c1cncc(CN(Cc2cnc(C3CC3)s2)CC2CCCO2)c1 +COCc1ccc(CNC(=O)CN2CCOCC2)cc1 +CN(CC(C)(CO)CO)C(=O)c1coc2ccccc12 +C#Cc1cccc(NCc2cc(C)ccc2OC)c1 +CCOC(=O)N(C)CC(=O)N1CCC(Nc2ccc(F)cc2)CC1 +Cc1c(-c2nc3ccccc3[nH]2)c(=O)n(-c2ccccc2)n1C +O=C(Cc1ccon1)NC1CCN(c2c(F)cccc2F)C1=O +COc1ccccc1CCC(=O)NCc1ccc(-n2cccn2)cc1 +NC(=O)C1CCN(C(=O)c2ccc(-c3ccc(Cl)cc3)s2)C1 +CCN(CC)C(=O)C(C)N1CCN(c2ccccc2O)CC1 +O=S(=O)(NCc1ccco1)c1cccc(OC(F)(F)F)c1 +CC(C)CC1COCCN1CC(=O)NCC1CC1 +CN(Cc1cccc(C#N)c1)C(=O)CCc1ncc(-c2ccccc2)o1 +COc1cc(C)nc(N(C)S(=O)(=O)c2ccc(C)cc2)n1 +CN(C)c1c(Cl)cccc1NC(=O)c1cccc2c1OCC(=O)N2 +CCOc1ccc(C(=O)c2nccn2C)cc1Cl +CC(Sc1nc(N)nc(N)n1)C(=O)NCc1ccccc1Cl +COc1ccc(Cn2c(CCCO)nc3ccccc32)cc1 +COCCCNC(=O)COc1ccc(C)cc1N +CCC(C)NC(=O)Cc1cc2c(cc1Br)OCCO2 +NC(=O)NC(CC(=O)Nc1cccnc1)c1ccccc1F +O=C(NCc1nnc2ccccn12)N1CCC(Nc2ccccc2)C1 +OCc1cn(Cc2cc(Cl)c3c(c2)OCCO3)nn1 +CC(C)(C)c1noc(Cn2nnc(-c3cccc(F)c3)n2)n1 +CCN(Cc1ccccc1)C(=O)c1ccc(OC)c(Br)c1 +Cn1c(=O)ccn(CC(=O)Nc2nccs2)c1=O +Cc1noc(CCC(=O)Nc2cc(F)ccc2Cl)n1 +COc1ccc(C)cc1Nc1ncnc(NCc2ccco2)c1N +COc1cc(C(=O)NC(C)CO)ccc1OC(F)F +Cc1noc(C)c1S(=O)(=O)Nc1ccc(N)cc1F +CCc1onc(C)c1NC(=O)NCC1(C)CCCO1 +CC(O)CN1CCN(C(=O)c2cccc(F)c2)CC1 +O=C(c1cccnc1OCC(F)F)N1CCCCCC1 +Cc1ccc(C)c2c(C)c(C(=O)NCCCn3ccnn3)[nH]c12 +CC(=O)N1CCc2cc(C(=O)OCC(=O)N3CCCC3)ccc21 +Cc1occc1C(=O)Nc1cc(Cl)ccc1N(C)C +CC(=O)c1c(-c2ccc(C)cc2C)cnn(C)c1=O +O=C(NCC1(c2ccccc2)CC1)c1ccc(-n2cncn2)cc1 +Cn1nccc1C(=O)Nc1ccc(Br)cc1 +COc1ccc(CC2CCCN2C(=O)C(C)OCC2CCCO2)cc1 +CCC1CN(C(=O)CNC(=O)OC(C)(C)C)CCO1 +COC1CCC(N(C)C(=O)CCCc2cccs2)CC1 +Cn1cc(C(=O)Nc2ccccc2CN2CCc3ccccc32)cn1 +O=C(CCc1cccnc1)Nc1cc(F)ccc1OCC(F)(F)F +O=C(c1csc(-c2ccsc2)n1)N1CCCC(O)C1 +Nc1nc(-c2c[nH]c3ccc(OCc4ccccc4)cc23)co1 +COC(=O)CCNS(=O)(=O)c1c(C)c(C)cc(C)c1C +O=S(=O)(NCC(O)c1ccsc1)c1ccc(Cl)cc1 +CC(C)(C)c1cc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)[nH]n1 +CC(C)(C)OC(=O)N1CCCN(c2nc3ccccc3[nH]c2=O)CC1 +CCc1noc(-c2ccc(C)c(NC(=O)N3CCC(O)C3)c2)n1 +O=C(CN1CCOCC1)N1CCN(CCc2ccccc2)CC1 +CCS(=O)(=O)c1ccc(NC(=O)c2cc(C)c(C)s2)cc1 +Cc1nc2ccccc2n(CC(=O)N(C)CCCC2CCCO2)c1=O +CN(CC(=O)OC1CCCCCC1)C(=O)c1ccccc1 +O=C(NCC1Cc2ccccc2O1)c1cccnc1OCC(F)F +O=C(C#Cc1ccc2c(c1)OCO2)N1CCN(Cc2ccco2)CC1 +Cn1ccnc1C(NC(=O)c1cnccn1)c1ccccc1F +COc1ccc(NC(=O)CCc2ccccn2)cc1C +CCC(=O)c1ccc(S(=O)(=O)CC(=O)NC)cc1 +Cc1nccn1-c1ncnc2c1cnn2Cc1ccc(Cl)cc1 +CCCc1nnc(NC(=O)NC2CCCC(C)C2)s1 +Cc1ccc(OCC#CCNC(=O)C2CC=CCC2)cn1 +COCCC(=O)NC1CCC2(CCC(=O)N2Cc2ccncc2)CC1 +CNS(=O)(=O)Cc1cccc(CNC(=O)Nc2ccccn2)c1 +O=C(c1cc2sccn2c1)N1CCN(C(=O)C2CCCCC2)CC1 +CCOC(=O)c1ccc(NC(=O)CNC(=O)c2ccccc2)cc1 +CN(Cc1ccc2ccccc2n1)c1nccc(-c2ccccn2)n1 +CC(=O)c1ccc(NC(=O)CCC(=O)c2ccc(C)s2)cc1 +O=C(Nc1cnn(Cc2ccc(Br)cc2)c1)C1CCC1 +C=C(C)COCCNC(=O)c1cnc(C2CCCO2)s1 +Cn1ccc(NC(=O)Cc2csc(-c3ccccc3Cl)n2)n1 +CCc1ccc(NC(=O)NC2CC(=O)N(C3CCCC3)C2)cc1 +Nc1cc(F)ccc1NC(=O)CCCn1ccccc1=O +COCCC1(CNC(=O)Nc2ccc3c(c2)COC3)CC1 +CC(C)CC(=O)NCc1cccc(NC(=O)C2CC2)c1 +CCOC(=O)N1CCN(S(=O)(=O)c2cc(C)ccc2OC)CC1 +CC(C)CCOc1ccc(NC(=O)c2ccncc2)cc1 +COc1ccccc1CNc1ccc(N)cc1C#N +CC(=O)N1CCN(CC(=O)NC(C)Cc2c(F)cccc2F)CC1 +Cc1cc(N(Cc2cn3ccsc3n2)C(C)C)ccc1C(N)=O +N#Cc1ccccc1NC(=O)CSc1nnc2n(N)cnn12 +CCC(C)NC(C(=O)OC)c1cc(F)c(F)c(F)c1 +CC(=O)c1ccc(SCC(=O)OC(C)C)cc1 +Nc1c(-c2ccccn2)nsc1C(=O)N1CCCCCC1 +COc1ccccc1CNc1nn2nnnc2c2ccccc12 +NC(=O)C1CCN(C(=O)Cc2cc(-c3cccs3)on2)CC1 +CCc1noc(CC)c1CC(=O)N1CCc2ccccc2C1 +CC(C)Cc1cc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)n(C)n1 +CC1CCN(S(=O)(=O)c2cc(F)ccc2F)C(C)C1 +CCOc1cc(C)ccc1NC(=O)Cn1ccc(=O)[nH]c1=O +CC1CCN(C(=O)CSc2nnc(-c3cccc(F)c3)n2N)CC1 +COC(=O)C1CCCN(C(=O)Nc2cccc(C)c2)C1 +CCc1ccc(NC(=O)c2cnc(C)c(N)c2C)cc1 +Cc1ccc2[nH]nc(-c3nc(-c4cccnc4)no3)c2c1 +CC(C)(C)CC(NC(=O)c1ccc(-n2cnnc2)cc1)c1cccnc1 +CC(C)(C)OC(=O)NCCNC(=O)c1ccsc1 +CCN(C(=O)CSc1n[nH]c(N)n1)C(C)c1ccc(F)cc1 +CC(C)(C)OC(=O)N1CCCN(C(=O)C2CCOC2)c2ccccc21 +CCCn1c(NC(=O)c2ccsc2)nc2ccccc21 +CCOC(=O)c1sc(NC(=O)c2ccn(C)c(=O)c2)cc1C +COC(=O)Nc1ccc(NS(=O)(=O)c2ccc(C)c(F)c2)cc1 +CS(=O)(=O)N1CCC(CNC(=O)NCc2cccs2)CC1 +Cc1ccccc1-n1ccnc1SCC(=O)N1CCCCC1 +Cc1ccc2c(cnn2CCC(=O)NC(C)(C)C)c1 +COc1ccc(C(N)C(F)(F)F)cc1OCc1cccc(Cl)c1 +COC(=O)c1ccc(Nc2cc(N)ccc2Cl)nn1 +Cn1ncc(Cl)c1C(=O)N1CCC2(CC1)OCCO2 +COc1nccnc1N1CCC(c2nccn2Cc2ccccc2)CC1 +COC(=O)CCC(=O)Nc1cc(Cl)ccc1Cl +Cc1ccc(C(C)NC(=O)CCCNC(=O)c2ccccc2)cc1F +CC(=O)Nc1ccc(C(=O)Nc2ccc(OC(F)F)c(F)c2)cc1 +CC(C)c1nc2c(C(F)(F)F)cccn2c1CO +CCOc1ccccc1CCNC(=O)c1ccc(C(=O)N(C)C)cc1 +O=C(COC(=O)c1cc2c(F)cccc2s1)NCC1CCCO1 +Cn1nc(C2CCN(C(=O)CCC3CCCC3)CC2)n(C2CC2)c1=O +CC(CCC(C)(C)C)NC(=O)NCc1cn(-c2ccccc2)nn1 +Oc1cc2c(cc1Cl)CCNC2c1ncccc1Cl +CC(=O)c1ccc(NC(=O)NCC(=O)Nc2ccc(Cl)cc2)cc1 +COc1ccc(NC(=O)Cn2cnc3c(cnn3CCO)c2=O)cc1 +Cc1cc2c(=O)[nH]c(-c3c(C)nc4scc(C)n34)nc2s1 +Cc1n[nH]c(C)c1-c1cc(-c2ccc3[nH]ccc3c2)c(C#N)c(N)n1 +CN(C)c1cc(C(=O)N2CCCC2c2ccsc2)ccn1 +O=C(COc1ccc(-n2cnnn2)cc1)N1CCCC2(CCOC2)C1 +O=C(NCCc1ccc(F)cc1)c1cccn2nccc12 +COC(=O)C(C)NC(=O)Nc1ccc(C(C)C)cc1 +N#CCCN1CCN(C(=O)c2ccc(Br)cc2)CC1 +CC1CCCCC1NC(=O)CSc1nc(N)cc(N)n1 +CC1CCCCN1C(=O)CNc1ccc(-n2cccn2)cc1 +Cc1cccnc1CC(NC1CCOc2ccccc21)C(F)(F)F +COc1ccccc1C1(C(=O)NCc2ccco2)CCOCC1 +CCc1nnsc1C(=O)NCCCNc1ncccn1 +CCCCCCN1C(=O)C(C)S(=O)c2ccc(N)cc21 +O=C(CCc1nc2ncccc2[nH]1)Nc1ccc(F)c(F)c1 +Cc1ccc(C(C)C)c(OC(=O)C(C)NC(=O)c2ccoc2)c1 +Cc1ccc(C(C)(O)CNC(=O)NC(C)c2csc(C)n2)o1 +CC(COCC(F)(F)F)NC(=O)c1cc2ccccc2c(=O)[nH]1 +CC1(NC(=O)CCC(=O)c2ccccc2)Cc2ccccc2C1 +COc1ccc(OC)c2c1cc(C(=O)Nc1cnn(C)c1)n2C +CC1(C(=O)NCCNc2cccc(F)c2C#N)CC1(Cl)Cl +O=C(Oc1ccccc1)C1CCN(c2ncccn2)CC1 +Cc1ccc(CC(C)NC(=O)c2ccnc(F)c2)s1 +O=C(CSc1nncs1)NCC#Cc1ccccc1 +CCOc1c(F)cccc1C(=O)N(CC)C(C)c1cccnc1 +Cc1cc(C)c(C(=O)Nc2cccc(C(F)(F)F)c2)c(=O)[nH]1 +O=S(=O)(Nc1cccc(-c2cn[nH]c2)c1)c1ccc2c(c1)CCC2 +CN1C(=O)CCc2cc(C(=O)Nc3ccccc3-n3cnnn3)ccc21 +Cc1ncsc1C(=O)NCc1ccccc1CO +C=CCN(CC=C)C(=O)c1ccc(=O)n(-c2ccccc2)c1 +COc1ccc(NC(=O)CSc2nncs2)c(N)c1 +N#Cc1cccnc1NCCNC(=O)Nc1nc2ccccc2s1 +CN(Cc1ccccc1)C(=O)c1cccc(CC#N)c1 +Cc1cc(C(=O)NCCCn2cccn2)c(C)n1C1CC1 +CCC1CCCN(C(=O)c2cc(C(N)=O)cs2)C1 +Cc1noc(C2CCCN(Cc3cccc(OC(F)(F)F)c3)C2)n1 +CC(c1ccc(-c2nnnn2-c2ccccc2)cc1)N1CCOCC1 +CCc1oc2ccccc2c1CN(C)C(=O)C(C)NC(N)=O +CC(C)n1nc(-c2ccccc2)cc1NC(=O)N1CCCC1 +O=C(CCOc1ccccc1)NCC(=O)Nc1cn[nH]c1 +O=C(Nc1nccs1)c1cccnc1Nc1cccc(F)c1 +Cc1noc(C)c1C(C)NC(=O)N1CCOC2(CCCC2)C1 +COc1ccc(NC(=O)c2cnn(C)c2N)cc1OC +O=C(OCc1cc(-c2ccc(F)cc2F)on1)c1ccc(=O)[nH]c1 +CN1CCC2(CN(C(=O)c3cccs3)CC2c2ccccc2)C1=O +COCCOc1ccc(S(N)(=O)=O)c2ccccc12 +Cc1cc(NC(=O)C2Oc3ccccc3OC2C)no1 +O=C(Nc1ncn(Cc2ccccc2Cl)n1)c1ccc(F)cc1 +CNc1snc(C)c1C(=O)Nc1cccc(-c2nc(C)c(C)o2)c1 +Cc1ccc(C(=O)NC(C(=O)NCc2cccs2)C(C)C)cc1 +Cc1nn(C)c(C)c1CCC(=O)NCCC(=O)NC1CCCC1 +CC(CNC(=O)NCc1cnn(C)c1)c1ccccc1 +CCn1cnc2cc(NC(=O)COc3ccc(Cl)cc3)ccc21 +O=C1CCC(C2NCCc3c(Cl)cccc32)N1 +CCCNc1nc(-c2cc(C)n(C3CC3)c2C)cs1 +O=C(Nc1ccccc1Cl)N1CCN(C(=O)C2CCCO2)CC1 +COc1ccccc1CN(C(=O)Nc1cn(C)nc1C)C1CCCC1 +COCC(=O)NC(C)c1cccc(N2CCOC2=O)c1 +Cc1[nH]ncc1C(=O)NCCc1nc2c(s1)CCCC2 +Cc1cc(C(=O)N2CCN(c3ccccc3C)CC2)c(C)o1 +CC(C)OC1CN(C(=O)CCc2nc(-c3ccccc3)no2)CC1O +CCc1n[nH]c(SC(C)C(=O)Nc2ccc(C)cc2)n1 +CC(C)N(C)S(=O)(=O)Nc1ccc(CC#N)cc1 +O=C(Nc1ccccn1)C(C(F)(F)F)C(F)(F)F +C#CCOc1ccc(C(=O)NCCc2cscn2)cc1 +CN(CC1CC1)C(=O)NCCc1ccc(S(C)(=O)=O)cc1 +Cc1ccc(S(=O)(=O)NCC(C)(O)c2cccs2)cc1Cl +CCn1ncc2cc(C(=O)N3CCN(C)CC3)c(N)nc21 +COc1ccc2cc(CCNC(=O)C3CCCC3)c(=O)[nH]c2c1 +Cc1cnn(CCC(=O)N2CCN(S(C)(=O)=O)CC2)c1 +CCCCC(=O)Nc1nnc(C2CC(=O)N(c3ccc(F)cc3)C2)o1 +COc1ccc(-c2nnc(-c3ccc(N)cc3)o2)cc1F +O=C1NCCN1c1ccc(-c2nc(-c3cc4ccccc4o3)no2)cc1 +Cc1ccc2c(c1)CCCN2C(=O)C1CN(C)CCO1 +Cc1occc1-c1nnc(NCc2ccccc2N2CCOCC2)o1 +CCOC(=O)CN(C(=O)c1cc2c(s1)CCC2)C1CC1 +CCc1noc(COc2ccc(C(C)=O)cc2OC)n1 +COc1ccc(CC(=O)N2CCCN(c3ncccc3F)CC2)cc1 +NS(=O)(=O)c1ccc2c(c1)CCN2CC(=O)N1CCOCC1 +CC(=O)c1cc(C(=O)N2CCOCC2c2cccn2C)n(C)c1 +Nc1cccc(S(=O)(=O)NCCc2ccccc2F)c1 +Cc1nc(COC(=O)c2cn(C)nc2-c2cccs2)oc1C +CCn1cnnc1CNC(=O)NC(C)c1cccc(N2CCCC2)c1 +CC1(C)CN(C(=O)C2CCCOC2)c2ccccc2S1 +O=C(Nc1cn[nH]c1)C1(c2ccc(Cl)cc2)CCOCC1 +CCOC(=O)C(O)Cc1nc2ccc(C)cc2s1 +Cc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)c(C)c1 +CCOC(=O)CNC(=O)N1CCC(CNC(C)=O)CC1 +CCOC(=O)C1CCCCN1Cc1ccccc1F +CCOCC1CCCN(C(=O)CCC(=O)c2ccccc2)C1 +CCOC(=O)CC(C)CNC(=O)Nc1nnc2ccccn12 +COCC(C)NC(=O)Cc1cc(=O)oc2cc(C)ccc12 +CC(=O)NCCC(=O)NCC1(c2ccccc2)CC1 +COc1cc(C(C)NCCc2nc[nH]n2)ccc1F +CCOC(=O)CNC(=O)C1(c2ccc(F)cc2)CC1 +COC(=O)C=C(C)c1ccc(-c2ccc3c(c2)OCO3)o1 +O=C1CC(c2nc(-c3ccncc3)no2)CN1CC(F)(F)F +CCC(Sc1nnnn1C1CC1)C(=O)Nc1ccc(OC)cc1 +CCOC(=O)N1CCc2c(sc(NC(=O)CC)c2C(=O)OC)C1 +CCOCC(=O)Nc1ccc(-c2ccccc2)cc1 +Cc1cnn(C(C)C2CC2)c1NC(=O)c1cc(C(C)C)no1 +CC(=O)Nc1cccc(-c2n[nH]c(-c3ccc(N)cc3)n2)c1 +Cc1sc(NC(=O)CC(C)C)nc1-c1ccc2c(c1)NC(=O)CO2 +CCc1nnc2n1CCN(C(=O)c1cc(Cl)cn1C)C2 +COc1nc(N(C)C(C)=O)nc(C)c1Br +Cc1nc2ccccn2c1CSc1nnc(C)n1CC(N)=O +CC1CCc2n[nH]c(-c3nc(-c4ccccc4)no3)c2C1 +CN(C(=O)Cc1csc(N2CCCC2=O)n1)C1CCCCCC1 +CC(=O)NC(c1ccccn1)C1CCCN(C(=O)C2CC2C)C1 +c1cncc(CNc2nc(N3CCCCC3)c3nccnc3n2)c1 +COCCCNc1ncc(-c2cc(C)no2)c(-c2ccc(C)o2)n1 +CC1(C)CCC(CC(=O)N2CCOCC2C2CC2)CC1 +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1C +CCOc1ccc(C(=O)c2cccc(N)c2)c(OCC)c1 +CNC(=O)c1ccc(NS(=O)(=O)c2ccccc2)c(C)c1 +O=C(NCc1ccc(F)cc1)c1cn2ccccc2n1 +Cc1cc(C)n(-c2ccccc2NC(=O)CCc2ccsc2)n1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)Cc1nccn1C +CC(C)OCc1ccc(C(=O)NCCc2nc3ccccc3[nH]2)cc1 +O=C(Nc1cccc(N2CCCC2=O)c1)c1ccccn1 +CCOC(=O)CCC(C)NC(=O)N1CCC(C)CC1 +Cn1cnc2c(N3CCC(C(N)=O)CC3)ncnc21 +Cc1nc(CCC(=O)N2CCC3(CCC(=O)N(C4CC4)C3)CC2)n[nH]1 +COC(=O)C(NS(=O)(=O)c1cccc(F)c1F)C(C)(C)C +O=C(COc1ccccc1)N1CC2CC(O)C(O)CC2C1 +Cc1ccc(CNC(=O)CSc2ccncc2)c(C)c1 +Cc1nn(C)c2[nH]nc(NC(=O)CCc3ccccc3)c12 +Cc1ccc(-c2nc(C(=O)Nc3ccccc3O)cs2)o1 +O=C(CCn1ccc2ccccc21)Nc1nc(-c2ccncc2)cs1 +Cc1nc2ccc(NC(=O)c3cnc(C4CCCO4)s3)cc2s1 +Cc1ccc(NC(=O)CCC2CCCO2)cc1Cl +CCNc1ccc(S(=O)(=O)N(C)C(CC)CC)cc1 +CC(C(=O)N(Cc1ccccn1)c1ccc(F)cc1F)n1cncn1 +CC(Cc1ccsc1)NC(=O)Nc1ccc2c(c1)COC2 +O=C(CCOCC(F)(F)F)NCc1nnc2ccccn12 +CCCOc1ccc(CNC(=O)c2cnn[nH]2)cc1 +CCc1ccc(N2CC(C(=O)NCC(F)(F)F)CC2=O)cc1 +Cc1cc(C(=O)OCC(=O)N2CCOCC2)c(C)n1C(C)C +O=C(NCc1nc(-c2cccs2)no1)NCc1cccs1 +O=C(Cc1nc2ccccc2c(=O)[nH]1)c1ccccc1F +NC(=O)NCCCCCC(=O)Nc1cccc(F)c1F +CC(NC(=O)c1cc(C(C)(C)C)n[nH]1)c1nc2ccccc2[nH]1 +CC1(C)CC(=O)c2cnn(-c3ccc(Cl)cc3)c2C1 +Cc1ccc(C(=O)CSc2nc(-c3ccncc3)n[nH]2)cc1C +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1CCC(O)CC1 +Cc1ccc(C(C)NC(=O)NC2CCN(S(C)(=O)=O)CC2)o1 +CC(C)(C)c1cc(NC(=O)COC(=O)C2(C)CC2(Cl)Cl)on1 +O=C(CNC(=O)NC1CCN(c2ccccc2)CC1)NC1CC1 +O=C(Cn1ncn2nccc2c1=O)N1CCCC(n2cncn2)C1 +N#Cc1cccc(NC(=O)NCc2ccnc(OC3CCC3)c2)c1 +CC=Cc1ccc(OCc2nnc(C)n2CC)c(OC)c1 +Cc1nc(N2CCCCC2C)nc2c1C(=O)CC(c1ccco1)C2 +COC(=O)c1ccc2c(c1)CC(CNC(=O)c1ccccc1F)O2 +CCOc1ccc(F)c(C(=O)NC2(c3noc(C)n3)CCC2)c1F +Cc1cccc(NCCSc2nnnn2C2CC2)c1 +CCc1nnc2n1CCN(C(=O)c1nc(C(C)C)ncc1Cl)C2 +CN1CCC(N(C)c2ncnc3c2CCCC3)C1=O +NC(=O)N1CCC(C(=O)N2CCCCC2c2nccs2)CC1 +Cc1cc(C(C)NC(=O)c2ccccn2)c(C)s1 +CCc1onc(C)c1NC(=O)N1CCN(C(C)c2ccsc2)CC1 +CC(=O)Nc1ccc(SC(C)C(=O)NCC2CCCO2)cc1 +Cc1nc(CN2CCN(c3nnnn3-c3ccccc3)CC2)cs1 +CCc1cnc(N2CCC3(CC2)CC(N2CCOCC2)C3)nc1 +CCN(C(=O)C1(C)CC1(Cl)Cl)C1CCCC1 +CCC1Oc2ccc(O)cc2N(CCN2CCOCC2)C1=O +COCCn1cnnc1C1CCCN1c1cnccn1 +Cc1ccc(C(=O)NCC(O)c2ccc(F)cc2)cc1 +Cc1ccc(C(=O)N2CCCC(c3noc(C(C)C)n3)C2)c(=O)[nH]1 +NS(=O)(=O)c1ccc(OCCN2CCN(CC(F)F)CC2)cc1 +CC(C)CCC(=O)NCc1cccc(S(N)(=O)=O)c1 +CCS(=O)(=O)Nc1ccc(C)c(N2CCCC2=O)c1 +Cc1ccccc1CC(=O)Nc1cc(C#N)cn1C(C)(C)C +Cc1nc(Cc2ccc(F)cc2)sc1C(=O)NCC(C)O +CC(C)c1noc(C2CCCCN2C(=O)c2cccnc2)n1 +CC1=C(C(=O)N2CCCCC2)C(c2cc(C)cs2)NC(=O)N1 +COc1ccccc1C(=O)c1cnc2ccccc2c1 +COc1ccccc1-c1nn(CC#N)c2c1CNCC2 +Cc1cnc(C(NC(=O)N2C(C)CCCC2C)C2CC2)s1 +O=C(Nc1ccccc1Cl)N1CC(c2nc3ccccc3[nH]2)C1 +Cc1ccc[nH]c1=NS(=O)(=O)c1cc(F)ccc1F +CCCCNC(=O)NCCCN1CCc2ccccc21 +Cc1cnc2c(c1Nc1ccc(F)c(F)c1)c(=O)n(C)c(=O)n2C +CC(=O)N(CCS(=O)(=O)N1CCCC1)Cc1ccncc1 +COc1ccc(-c2ncnc3c(C)csc23)c(OC)c1 +CN(C(=O)c1cncc(Br)c1)c1ccc(O)cc1 +CC(C)OC(=O)c1cc(-c2ccc(O)cc2)nn1C +COc1ccc(CCC(=O)Nc2cc(-c3ccccn3)no2)cc1 +CCOCC(=O)Nc1ccnn1Cc1ccc(C)cc1 +CC1OCCN(Cc2ncccc2C(F)(F)F)C1C +Cc1c(CCC(=O)NCc2ccccc2)cnn1C +CCC(=O)Oc1ccc(C(=O)Nc2ccccc2C#N)cc1 +CC(C)CN1CCOC(COC(=O)c2cc(C(N)=O)cn2C)C1 +Cc1ncsc1C(=O)Nc1nc2c(s1)CC(C)CC2 +O=C(c1cccc(C(F)(F)F)c1)N1CCOCC1c1ncon1 +Cc1cccc(CNS(=O)(=O)c2ccc(N3CCCC3=O)cc2)c1 +Cc1noc(CCC(=O)N2CC=C(c3ccccc3Cl)CC2)n1 +CC(=O)NCCNC(=O)c1cc2cnn(C(C)C)c2nc1C +Cc1ccccc1CCNC(=O)c1ccn(-c2ccccc2)n1 +Cc1ccc(C)c(S(=O)(=O)Nc2ccc(Cl)cn2)c1 +O=C(c1ccco1)N1CCOC2C(OCc3ccncc3)CCC21 +COc1cc(OC)c(C(=O)N(C2CC2)C(C)C2CC2)cc1OC +CC(Cc1ccc(O)cc1)N(C)C(=O)c1ccncc1F +O=C(C1CCCCC1)N1CCCC(c2nnc(-c3cccs3)o2)C1 +Cc1ccc(N2CCC3(CCC(=O)N3Cc3cccnc3)CC2)nn1 +CCOC(=O)c1cnn(-c2nc3c(c(=O)[nH]2)CCCC3)c1N +COc1c(Cl)cccc1NC(=O)N1CCCC(CO)C1 +CCCc1nnc(NC(=O)NC2CCN(c3ccccc3)C2=O)s1 +COc1ccc(C(=O)NC2CC(=O)N(CC(C)(C)C)C2)o1 +COC(=O)c1cc(NC(=O)N2CCCC2)ccc1OC +CCOC(=O)Cn1c(C(C)NC(=O)C(C)(C)C)nc2ccccc21 +CN(C)C(=O)C1CC2CN(c3ncc(F)cn3)CC1O2 +COc1ccc(S(=O)(=O)CCNC(=O)C(C)(C)C)cc1 +COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2sc(C)nc2C)c1 +CCc1cccc(CC)c1NC(=O)c1cnc(C2CCCO2)s1 +N#CC(C#N)C(c1ccsc1)c1c(O)n[nH]c1-c1ccccc1 +Cc1cccc(NC(=O)COC(=O)COc2ccc(F)cc2)c1 +CC(=O)N1CCCn2nc(CNS(=O)(=O)N(C)C(C)C)cc2C1 +CC(=O)Nc1nc2ccc(NC(=O)C(C)(C)C)cc2s1 +Cc1nnc2sc(-c3ccc(Cl)c(N)c3)nn12 +CC(C)OCc1ccccc1CNS(=O)(=O)c1cnn(C)c1 +COc1cccc(N2CCN(C(=O)c3ccc(C)s3)CC2)c1 +Cc1csc(C2CCCN(C(=O)CC3=CCCCC3)C2)n1 +Cc1nnc(NC(=O)Cn2nc(-c3ccccc3F)ccc2=O)s1 +O=C1Cc2cc(NC(=O)c3cc(Cl)c4c(c3)OCCO4)ccc2N1 +N#Cc1cc(C2NCCc3c(O)cccc32)ccc1F +Cc1cnn(-c2ccc(NCc3nsc(N(C)C)n3)cc2F)c1 +O=C1Cc2cc(NC(=O)c3ccccc3C(F)(F)F)ccc2N1 +CCC(NC(=O)CN(C)C(=O)c1cccs1)C(C)C +CCCn1cc(S(=O)(=O)NCc2cccc(F)c2)c2cccnc21 +O=C(Nc1ccc(CN2CCCC2=O)cc1)c1cccc(F)c1 +CCCC(=O)N1CCCC(C(=O)Nc2cc(C)cc(C)c2)C1 +CN(CC(N)=O)C(=O)Cc1ccc(OC(F)(F)F)cc1 +COCc1nc(C(=O)NCc2cc(C)oc2C)cs1 +COc1ccc(OC)c(CN(C)C(=O)c2ccc(O)c(Cl)c2)c1 +CS(=O)(=O)NCC1CCCN(C(=O)Nc2ccc(Cl)cc2)C1 +COC(=O)c1sc(-c2ccc(S(N)(=O)=O)cc2)nc1C +Cc1nnc2n1CCN(CC(=O)Nc1sc3c(c1C#N)CCC3)C2 +O=C(Nc1ccc(F)cc1F)c1ccnn1C(F)F +CC1CC(=O)c2cnc(N3CCN(c4ccccc4F)CC3)nc2C1 +CC(=O)Nc1ccc(C(=O)Nc2cccc(-c3noc(C)n3)c2)cc1 +O=C(c1ccc(-c2cccc3cnccc23)o1)N1CCOCC1 +O=C(Cn1c(C2CC2)nc2ccccc21)NCc1ccsc1 +CC1CCCC(N(C)C(=O)NC(C)C2CCCO2)C1 +CCn1nc(C)c(CNCC(O)(c2ccccc2)C(F)(F)F)c1C +CCC(Sc1ncc(C(C)C)n1C(C)C)C(N)=O +Nc1nc(CSc2ccc(C(F)(F)F)cn2)nc2ccccc12 +CCCNC(=O)Cc1c(C)nc2nc(C3CCCCC3)nn2c1C +Cc1cc(C(=O)NCCOc2ccccc2)c2c(C)nn(C)c2n1 +CC(=O)Nc1cc(C(=O)Nc2ccccc2C(=O)C(C)C)ccc1F +FC1(F)CCN(Cc2ccccn2)CC12CCN(c1cnccn1)C2 +COc1ccc(CCNc2nccn(C)c2=O)cc1 +Cc1ccc(-n2cnc(C(=O)NCCCN3CCOCC3)n2)cc1 +CC(=O)NC(C)(C)c1noc(Cc2coc3cc(C)c(C)cc23)n1 +CCOC(=O)C1CCCN1C(=O)CCC1CCCC1 +COCCCCn1nnnc1-c1ccccc1F +COc1ccccc1NC(=O)C(C#N)Cc1ccccc1 +COc1ccccc1-c1cc(C(=O)NCC(C)C)nn1C +COC(=O)C1Cc2c[nH]c3cccc(c23)C(CC(C)C)N1 +CC1CCc2n[nH]c(C(=O)NCCN3CCCC3=O)c2C1 +O=C1CCC2C(CCN2C(=O)c2cscn2)N1Cc1ccncc1 +O=C(N1CCOCC1)N1CCOCC(Oc2cnccn2)C1 +COc1ccc(S(=O)(=O)N2CCCC(C)C2)c(C)c1 +Cc1cccc(OCCSc2nnc(C(F)(F)F)n2N)c1 +COC(=O)c1ccc(NC(=O)C2CC3C=CC2C3)cc1 +CCn1cc(C2=Nc3ccccc3S(=O)(=O)N2)cn1 +COc1cc(NC(=O)N(CC(C)C)CC(C)C)ccc1NC(C)=O +COc1cccc(-c2c(-c3ccco3)noc2N)c1 +COc1ccc2c(O)cc(C(=O)NC(C)C)cc2c1OC +CCC(C)c1ccc(C(=O)Cn2c(=O)c(C#N)cn(CC)c2=O)cc1 +CC(C)OCC(=O)N1CCC(N2CCNC2=O)CC1 +CCCCc1ccc(C(=O)CN2CCN(C(C)=O)CC2)cc1 +O=C(CSc1ncnc2sc3c(c12)CCC3)N1CCCCC1 +CC(C)CSc1cc2c(cc1N)OCC(=O)N2 +CN(C(=O)COCC1CC1)c1cccc2ccccc12 +CN(C(=O)CCC(F)(F)F)c1ccccc1S(C)(=O)=O +O=C(NCC(=O)N1CCCC1)NCc1cccc(Cn2cccn2)c1 +CC(=O)c1ccc(C)n(Cc2cccc3ccccc23)c1=O +CCn1cnnc1CNS(=O)(=O)c1ccc(Br)cc1 +CC(C)c1ccc(S(=O)(=O)Nc2ccc3oc(=O)[nH]c3c2)cc1 +O=C(CC1CCCO1)Nc1nc(C(F)(F)F)cs1 +O=C(NCCCO)Nc1cccc(C(=O)Nc2cccc(F)c2)c1 +CC(CO)(NC(=O)NCc1cccc(OCC#N)c1)C1CCCCC1 +O=C(NCCC(=O)N1CCCC1)Nc1cnn(CC2CCCO2)c1 +CC(C)CNC(=O)c1c(F)ccc(Br)c1F +CC(NC(=O)CCn1c(=O)oc2ccccc21)c1ccccc1 +CCOC(=O)c1ccc(OCc2nnc(C)o2)cc1 +CCCc1nnc(NC(=O)c2cc(C)nn2CC)s1 +COc1ccc(C=Cc2ccnc3nc(N)nn23)cc1 +COc1ccc(CNC(C)C(N)=O)cc1OC(F)F +Cc1cc(Cl)ccc1OC(=O)COc1ccc(CC(N)=O)cc1 +O=C1COc2ccc(CO)cc2N1Cc1ccc(F)cc1 +Cc1cc(C)c(C#N)c(SCC(=O)NCc2ccc(F)cc2)n1 +O=C(NCCc1ccccn1)Nc1cc2c(cc1Cl)OCCCO2 +O=C(Nc1cccc(F)c1)c1cncc(Br)c1 +Cc1cccnc1CN1CC(F)C(OCc2nc3ccccc3o2)C1 +O=C(NC1CCSc2ccccc21)c1cc2ccccc2o1 +Cc1ccc(F)cc1C(=O)NCc1cccc(S(N)(=O)=O)c1 +CCNC(=O)c1ccc(NC(=O)N(C)Cc2cccn2C)c(C)c1 +CCCc1[nH]nc(C(=O)NC2CCCC2C)c1N +CCCC1CN(C(=O)Nc2cnn(-c3ccccc3Cl)c2)CCO1 +O=C(NCCc1ccc(O)cc1)c1cc(Cl)c[nH]1 +Cc1csc(N(C)C(=O)C2CCN(c3ccc(C#N)cn3)CC2)n1 +CCNC(=O)c1ccc(CNC(=O)c2ccccc2Cl)cc1 +C=CCC1(CC=C)CCCCN1C(=O)c1ccoc1 +Nc1ccc(C(=O)NCc2ccc(F)cc2)c(Cl)c1 +O=C(CCCNC(=O)C1CC1)Nc1cccc(-n2ccnc2)c1 +CCOC(CC)C(=O)N1CCN(c2nnnn2-c2ccccc2)CC1 +COc1ccc2[nH]c3c(=O)n(CCN4CCCC4=O)cnc3c2c1 +C=CCNC(=O)c1ccc(NC(=O)c2cnc3[nH]nc(C)c3c2)cc1 +Cc1ccn(C)c(=O)c1NC(=O)C1CC1c1ccc(Cl)cc1 +CCc1ccccc1OC1CN(C(=O)C(C)NS(C)(=O)=O)C1 +CCN(CC)C(=O)Cn1cc(C(C)=O)c2ccccc21 +CCN(CC)S(=O)(=O)c1ccc(NC(=O)CC(C)C)cc1 +CCNC(=O)CNC(=O)NCc1cccc(OC(F)F)c1 +CCOCC1CCCN(C(=O)NC(C)c2c(C)noc2C)C1 +O=C(Nc1cccc(-n2cnnn2)c1)c1cc2c(F)cccc2s1 +COc1cccc(CCNC(=O)c2ccc(=O)n(C)c2)c1 +N#CCC(O)(c1ccccc1)c1ccccc1Cl +CCC(C)NC(=O)NCCOc1ccc(OC)cc1 +CCCNC(=O)C1CC(=O)N(c2ccc(C)c(Cl)c2)C1 +O=C1CC(C(=O)NC2(c3ccc(F)cc3F)CCCC2)CN1 +CC(NC(=O)Nc1ccn(-c2ccccc2)n1)C(=O)NC(C)(C)C +Cc1ncc(C(=O)NCc2nc(-c3ccccc3)no2)c(C)n1 +COC(=O)CCCn1c(CCO)nc2ccccc21 +COc1ccc(OC)c(NC(=O)c2sc(-n3cccc3)nc2C)c1 +COc1ccnc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)c1 +CCCn1nc(C(=O)Nc2cc(F)c(OC)cc2OC)ccc1=O +CCOc1ccc(C(F)(F)F)cc1NCc1nc(C)cs1 +CN(C)C(=O)C1CCCN1C(=O)Cc1cccc(F)c1 +Cc1csc(C(C)(C)NC(=O)c2cccc(OCC(F)F)n2)n1 +Nc1cnoc1-c1c[nH]c2c(Br)cccc12 +COc1ccc(CNC(=O)Nc2ccc(C)c(F)c2)cc1OC +Cc1cccc(NC(=O)c2cc3sccn3c2)c1 +Cc1ccc(C(=O)N2CCc3cc(N)ccc32)cc1O +COC(=O)N1CCC(CNC(=O)NC2CCCC2)CC1 +O=C(NCCNC(=O)C1CC2CCC1O2)c1ccc(Cl)cc1 +N#Cc1cccc(C(=O)Nc2ccc(C(=O)N3CCCCCC3)cc2)c1 +Cc1ccc(NCC(=O)N(C)C)c(C)c1S(=O)(=O)NC1CC1 +Cc1cc(C)cc(-c2nnc(SCCCN3CCOC3=O)o2)c1 +Cc1ccccc1Cn1c(C)cn2c3c(=O)n(C)c(=O)n(C)c3nc12 +O=C(c1ccccn1)N1CC2CN(c3ccsc3)C(=O)C2C1 +CC(C)OC(=O)c1cc(=O)[nH]c2c(Cl)cccc12 +CCc1c(C)nc2n(c1=O)CC(C(=O)NC(C)(C)C)CS2 +COc1ccc(C)cc1S(=O)(=O)N(CCO)C(C)C +CCC1CN(C(=O)NC2CCN(C(C)=O)CC2)CCO1 +Cc1ccc(-c2nnc(SCC(=O)c3cnn(C)c3)o2)cc1C +CC(O)CC(C)CNC(=O)Nc1ccc(Oc2ccc(F)cc2)nc1 +CC(C)CCN(C)C(=O)c1ccccc1S(C)(=O)=O +CC1CCN(C(=O)c2sccc2OC(F)F)C(C)C1 +CC(c1ccc(F)cc1)=c1sc2n(c1=O)CCN=2 +CC(c1ccco1)N(C(=O)NCc1ccnn1C)C1CC1 +CN1CCc2c(c(C#N)nn2-c2ccc(F)c(F)c2)C1 +COC(=O)C1CCN(C(=O)C(C)C)c2ccccc21 +C#CCN1CCN(C(=O)CNc2ccc(Cl)c(F)c2)CC1 +COc1ccc(NC(=O)c2c(C)nn(C)c2C)cc1C +COCCN1CCN(Cc2c[nH]nc2-c2ccc(F)cc2)CC1=O +Cc1cccc(NC(=O)C2CCCN2S(C)(=O)=O)n1 +CNS(=O)(=O)c1cccc(NCC2CCCCC2)c1 +COc1ccc(C(NC(=O)c2ccncc2)c2ccc(OC)cc2)cc1 +O=c1ccc(CNCc2cccc(F)c2F)c[nH]1 +CCn1nc(C(=O)N2CCCCC2c2ccc(F)cc2)cc1C +CC(Cn1nnc2ccccc21)NC(=O)Cc1cccs1 +Cc1ccccc1CC(=O)N1CCN(C(=O)CC(C)(C)C)CC1 +CC(C)c1nnc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)s1 +CCCc1nc(NCc2ccncc2)c(N)c(OCC)n1 +Fc1ccc(OCCN2CCN(c3ncccn3)CC2)cc1 +COC(=O)c1nnn(-c2ccc(Br)cc2)c1N +O=C(Cc1n[nH]c2c(Cl)cccc12)NCC(=O)NC1CC1 +Cc1ccc(OCC(=O)N2c3ccccc3CC2C(N)=O)cc1 +CCNC(=O)c1ccc(CNC(=O)N2CCCC(NC(C)=O)C2)cc1 +Cc1cc(C(=O)NC(C)C)ccc1NC(=O)NC(C)C(C)CO +O=C(NCCCN1CCOC1=O)c1ccn(-c2cccc(Cl)c2)n1 +CN(C)C(=O)COc1cccc(NC(=O)c2ccc[nH]2)c1 +O=C(NCc1ccccn1)c1cccc(NC(=O)c2ccccc2)c1 +Cc1ccc(C)c(NC(=O)c2cc3cccnc3[nH]c2=O)c1 +COC(=O)c1ccn(CSc2nc(C)cc(C(F)(F)F)n2)n1 +O=C(CCNC(=O)c1cccn2cncc12)NCc1cccs1 +CC1CN(C(=O)Cn2cc(C(F)(F)F)ccc2=O)CC(C)O1 +CCc1ccc(N2CC(C(=O)N3CCCCCC3)CC2=O)cc1 +CCN1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 +COc1cccc2c1OCC(NC(=O)C1CC1C)C2 +COc1ccc(C(=O)NCCC(O)c2ccco2)cc1OC +COc1cccc(NC(=O)CN2C(=O)CCn3nc(C)cc32)c1 +CC(C)(C)C(=O)CNC(=O)CCn1ncc2c(Cl)cccc21 +CC(=O)c1ccc(C(=O)Nc2cc(Br)c[nH]c2=O)cc1 +COc1ccccc1N1CCN(CC(=O)NCc2cccs2)CC1 +Cc1cc(C)c(NC(=O)c2cc(-c3ccccc3)[nH]n2)c(C)c1 +COc1cc(NC(=O)NCC(C)C)cc(OC)c1 +CC(C)(C)NC(=O)COC(=O)C1(O)CCCCC1 +CCC(NC(=O)c1cn(C)nc1C(C)(C)C)c1ccc(OC)cc1 +O=C1CCN(C(=O)c2cc(Cl)ccc2Cl)CC1 +CS(=O)(=O)c1ccc(-c2ccc(F)c(O)c2)cc1 +Cc1nc(C)c(-c2nnc(SCCO)o2)s1 +CC(=O)c1ccc(NC(=O)N(C)Cc2ccc3c(c2)OCO3)cc1C +COc1ccc(F)cc1C(=O)C1CCCN(C(=O)C2(CO)CC2)C1 +Cc1cccc(CN(C(=O)CC2C=CCC2)C2CC2)c1 +CNC(=O)C1CCCN1C(=O)c1cc(N)cc(N)c1 +Cc1ccc(CNC(=O)Cn2[nH]c(=O)c3ccccc3c2=O)cc1 +COC(=O)c1[nH]c(C)cc1NC(=O)c1ccc2c(c1)NC(=O)CS2 +CCOc1cc(=O)n2c(c1C(=O)NCc1ccc(C)cc1)CCCC2 +O=C(Nc1cnn(-c2ccccc2F)c1)c1ccc(OC(F)F)cc1 +O=C(COC(=O)C12CC3CC(CC(C3)C1)C2)NCC1CCCO1 +CCCCn1nccc1NC(=O)Cc1c[nH]c2ccc(F)cc12 +NC(=O)c1csc(NC(=O)c2ccnc(OC3CCC3)c2)n1 +COCCCN(C)C(=O)NCc1ccccc1Cl +Cc1cc(CCNS(=O)(=O)c2cccc(Cl)c2C)on1 +CCn1cc(C(=O)OCC2Cc3ccccc3O2)cn1 +CC(NC(N)=O)C(=O)NCCNC(=O)OC(C)(C)C +Cc1cc(NC(=O)N2CCC(C)CC2)ccc1-n1cnnn1 +COC(=O)c1ccc(COCC(F)(F)C(F)F)cc1 +C#CCOC1OC2COC(c3ccccc3)OC2C(O)C1NC(C)=O +COC(=O)C1=C(OC)C(=O)N(c2ccc(F)cc2)C1 +CC(C)(C)CC(=O)Nc1cccc(-n2cnnn2)c1 +O=C(NCC1COCCO1)N1CCCC1C1CCCC1 +Cn1ccc2nc3ncnn3c(-c3ccccc3)c2c1=O +Cc1ccc(S(C)(=O)=O)cc1C(=O)OCC(=O)N1CCOCC1 +CCOc1ccc2[nH]c(C(=O)NC3CCCOC3)cc2c1 +NC(=O)c1ccc(C(=O)Nc2nc(C3CC3)cs2)cn1 +Cc1ccc(N2CCCC2=O)c(C(=O)N2CCCCC2)c1 +Cc1cccc(NC(=O)C(CC(C)C)N2Cc3ccccc3C2=O)n1 +CC(Cc1ccccc1F)NC(=O)c1ccc(S(N)(=O)=O)cc1 +Nc1ncccc1C1NCCc2cc(C(F)(F)F)ccc21 +COC(=O)c1cc(Br)c(O)c(Br)c1 +COc1cc2c(cc1OC)CN(C(=O)COc1ccccc1F)CC2 +CCOc1ccc(CN(C)C(=O)c2ccc(CNC(N)=O)cc2)cc1 +Cc1noc(-c2csc(S(=O)(=O)NC3CCCC3)c2)c1C +O=c1[nH]nc(SCc2ccccc2F)n1CC1CCCO1 +COc1cccc2c1CCNC2C1CCCN1C(C)=O +COc1ccnc(NC(=O)c2cc(C)cc(OC)c2O)c1 +Cc1cc(C(=O)Nc2cc(Br)c(=O)n(C)c2)sc1C +COC(=O)CC(NC(=O)c1ccc2c(c1)OCO2)c1cccs1 +COCc1ccc(C(=O)NC(C)C23CC4CC(CC(O)(C4)C2)C3)o1 +Cc1cc(CNC(=O)c2ccc(-n3c(C)c[nH]c3=O)cc2)ccc1F +CN(C)c1ccc(S(=O)(=O)N(C)Cc2ccccc2)cc1N +C#CCN1CCN(C(C)C(=O)NCc2ccccc2Cl)CC1 +CCN(CC)C(=O)c1ccccc1NC(=O)N1CCC(CO)CC1 +CSc1cccc(NC(=O)Nc2cnn(CC3CCCO3)c2)c1 +COc1cc(N)ccc1Nc1nc(-c2cccnc2)cs1 +COc1ccc(CNc2ncnc(-n3cnc4ccccc43)c2N)cc1 +CCN(CCC#N)Cc1nc(N)c2cnn(C)c2n1 +CCCn1c(CO)nc2cc(C(F)(F)F)ccc21 +COc1cccc2cc(C(=O)N3CC(C)CC(C)C3)c(=O)oc12 +O=C(c1scnc1C1CC1)N1CCOC2(CCCCCC2)C1 +Nc1c(Sc2ccccc2)ncnc1-n1ccnc1 +Cc1cccc(Nc2ncnc(NC(C)C)c2N)n1 +Cc1nc(C)c(CC(=O)NC(c2ccc(F)cc2)C2CCC2)c(=O)[nH]1 +N#Cc1ccccc1NCCC(O)c1ccc2c(c1)CCC2 +CCCC(O)c1ccc2c(c1)CN(C(=O)CC(C)C)CC2 +CCN(CC1CC1)C(=O)c1ccccc1OCc1c(C)noc1C +CC(COc1ccc(F)cc1)NC(=O)N(C)Cc1ccccn1 +CC(=O)N(CCc1ccccc1)CC(=O)N=c1[nH]cc(C)[nH]1 +Cc1ccc(NC(=O)CC2C=CCC2)cc1N1CCCS1(=O)=O +Cc1ccccc1CCC(=O)N1CCN(C(=O)c2ccsc2)CC1 +Cc1ccc(S(=O)(=O)CCC(=O)NC2CCCCCC2)cc1 +Cc1ccccc1C1CCCN1C(=O)COc1ccccc1C#N +Cc1ccccc1C(=O)OCC(=O)Nc1nccs1 +CN(CC(=O)N1c2ccccc2NC(=O)C1(C)C)c1ccccc1 +CNC(=O)C(CC(C)C)NC(=O)c1[nH]c(C)c(C(C)=O)c1C +CC(C)(C)C(NC(=O)CCc1nncn1-c1ccccc1)C(N)=O +Fc1cc(CSc2ncnc3sccc23)c2ncccc2c1 +Cn1ncc2c1CCCC2NC(=O)CCc1ccc(-c2ccccc2)o1 +Cc1occc1C(=O)NCC(=O)NCC1CC1C +CCC(CC)C(=O)Nc1ccc(NS(=O)(=O)CC)cc1 +COc1ccccc1C(=O)N(CCC#N)c1ccccc1 +CC(C)NC(=O)N(Cc1ccccc1OS(C)(=O)=O)C1CC1 +CCOc1ccc2c(c1)CN(C(=O)Nc1cccc(COC)c1)CC2 +CCn1c(=O)n(CC(=O)NCc2ccc(F)c(C)c2)c2ccccc21 +COCC1COCCC12CCN(C(=O)c1cccs1)CC2 +Cc1noc(C)c1CCCNS(=O)(=O)c1c(F)cccc1F +CCOC(=O)c1ccc(OC(=O)c2ccc(C)nc2)cc1 +CC(=O)Nc1ccc(CNC(=O)C2CCOC2)cc1 +CC(=O)N1CCc2cc(CNC(=O)C3CC3)ccc21 +Cc1ccncc1C(=O)c1cncc(Br)c1C +CNC(=O)c1ccc(OC2CNC(C(=O)OC)C2)cc1 +CCS(=O)(=O)c1ccccc1NCc1scnc1C +COc1cccc(C(=O)CSc2nc3cccnc3n2C)c1 +COC(C)C(=O)N(Cc1ccc(Cl)c(Cl)c1)C(C)C +O=C(COC(=O)c1ccsc1)Nc1ccccc1N1CCCC1=O +Cc1ncc(CNC(=O)Nc2ccccc2SCC(N)=O)s1 +NC(=O)c1cc(-c2cc(O)cc(Cl)c2)ccc1Cl +CCOC(=O)c1cc2c(nc1N)CC(C)(CC)OC2 +COc1ccc(CCNC(=O)Cc2ccccc2N)cc1 +CC(C)c1ccc(C2CC2C(=O)Nc2nc(S(C)(=O)=O)n[nH]2)cc1 +Nc1nccc(N2CCC3(CCC(=O)N(C4CCCC4)C3)CC2)n1 +CC1(C)CN(C(=O)C(C)(C)C)C(c2ccccc2)CN1 +COC(=O)NCC(=O)NC(c1cccc(C(F)(F)F)c1)C(C)C +CC1(C(N)=O)CN(C(=O)c2csc3c2CCCC3)CCO1 +CC(C)CCN1CC(C(=O)NC2=CC3N=CC=C3C=C2)CC1=O +CC(CNC(=O)c1cccc(OCC(F)F)n1)N1CCOCC1 +Cc1nc2ccc(NC(=O)CCCNC(=O)C3CC3)cc2s1 +COC(=O)c1sc(NC(=O)c2cnns2)nc1C1CC1 +O=C1CCC(COC(=O)CCNC(=O)c2cccs2)N1 +CCOC(=O)c1cccc(NC(=O)c2cc(C(F)(F)F)n(C)n2)c1 +COc1ccc(CC(=O)Cc2ccccc2F)cc1OC +CCCCNC(=O)c1ccc(OC)c(OC)c1OC +O=C(NCCCO)c1cccc(Oc2ccccc2)c1 +CN(C(=O)Nc1cccc2cccnc12)C(C1CC1)C1CC1 +CCCC(CC)NC(=O)c1ccc(S(N)(=O)=O)cc1 +COc1cc2c(cc1-c1c(C#N)c(N)nc3c1COC3C)CCC2 +CCc1cnc(CN(C)C(=O)c2cnn(-c3ccncc3)c2C)s1 +COCCN(CC(=O)N(C)C)C(=O)c1ccccc1C +CN(C)CC1NCCc2cccc(OC(F)F)c21 +CC(Sc1nncs1)C(=O)NCC1CCC1 +Cc1cc(C(=O)N2CCN(C(=O)N3CCCCC3)CC2)on1 +CC(C)CC(=O)N1CCN(c2ncc(Cl)cc2N)CC1 +Cc1cc(C(=O)NC2CCCC2)ccc1-n1nnc2cccnc21 +COc1nc(Oc2ccc(C(N)=O)cc2)ccc1N +Cc1ccc(OCC(=O)NCC2(c3cccs3)CCOCC2)cc1 +CCc1nc2nnc(C(=O)Nc3ccc(OC)cc3)c(C)n2n1 +CCCNS(=O)(=O)c1ccc(Cl)c(OCC)c1 +O=C(NCCC(=O)N1CCCC1)NCCc1ccccc1Cl +Cc1ccccc1C1CC1C(=O)N1CCc2[nH]ncc2C1 +Cc1cc(NC(=O)CCc2c(C)nn(C)c2C)n(C2CCCC2)n1 +Cc1cc(C(=O)N2CCCCC2c2nncn2CC2CC2)nn1C +CC(C)CN(C)C(=O)CNC(=O)NC1CCCCC1 +CC(=O)c1cc2cc(C(=O)NC3CCCC3)cnc2[nH]1 +C=CCN(C)c1c(N)n(CCCC)c(=O)[nH]c1=O +O=C1c2ccccc2NC(c2cccc(Cl)c2)N1C1CC1 +Cc1ccc2ncc(C(=O)N3CCC(Oc4cccnc4)C3)n2c1 +CC(=O)N1CCC(C(=O)NCC2(c3ccc(F)cc3F)CC2)CC1 +O=S(=O)(N1CCCC1)N1CC(CO)CC(CN2CCOCC2)C1 +CC1(CCC(=O)N2CC(CO)CC(CN3CCOCC3)C2)CC1 +O=C(Nc1cccc(C(F)(F)F)c1)N1CCOCC1C1CC1 +O=C(c1ccc(C(F)(F)F)nc1)N1CCCC1c1cccs1 +Cc1cncc(C2NCCc3c(OC(C)C)cccc32)c1 +CCn1cnnc1CCNc1nc(-c2ccccc2)nc2c1CCC2 +Cc1csc(-c2cc(C3CCOC3)c(C#N)c(N)n2)c1 +CNC(=O)COc1ccc(S(=O)(=O)N2CCOCC2)cc1 +CCCCNC(=O)c1cc2c(=O)n3ccccc3nc2s1 +Cc1ccc(CNC(=O)C(c2ccccc2F)N2CCOCC2)s1 +CC(C)n1ccc(C(=O)Nc2nc(C(C)(C)C)cs2)n1 +COc1cccc(C2CCCCN2C(=O)CCn2ccc(C)n2)c1 +CC(C#N)(NC(=O)CSc1ncnc2sccc12)C1CC1 +CCCN(C)C(=O)c1cccc(N2CCNC2=O)c1 +CCC(C)(C)NC(=O)CNc1ccccc1COC +Cn1nccc1C(=O)N1CC2CCCC2(COc2ccccn2)C1 +CC(C)NC(=O)Nc1ccc(C(=O)N2CCC2)cc1 +CC(NC(=O)Cc1cc(Cl)c2c(c1)OCCO2)c1ccco1 +Cc1cc(CN(C)C(C)CC#N)cc(C)c1OCC(F)(F)F +COc1ccc(-c2noc(CC(=O)N(C)Cc3ccccc3)n2)cc1 +COc1cc(CCNC(=O)c2cccc(-n3cnnn3)c2)ccc1C +Cc1ccc(C(C)C)cc1OCC(=O)N1CCOCC1C +CCC(=O)N(Cc1cc2cccc(C)c2[nH]c1=O)c1ccccc1 +CC(=O)NCC(=O)N1CCN(C(=O)c2ccco2)CC1 +C=CCn1cnnc1SCc1cccc(C(N)=O)c1 +Fc1cc(CNCCc2ccccn2)cc(F)c1F +CC(=O)N1CCc2cc(NC(=O)Cn3c(C)c(C)sc3=O)ccc21 +COc1ccc(Br)cc1CN(C)C(=O)Nc1cn[nH]c1 +CCOc1ncccc1C(=O)Nc1ccc(CN2CCOCC2)cc1 +O=C(CN1CCOCC1)Nc1ccnn1Cc1ccccc1Cl +CC(C(=O)NCC(F)(F)F)S(=O)(=O)c1ccccc1F +COc1cccc(CCNC(=O)c2ccc(SC)cc2)c1 +Cc1cc(C(=O)Nc2ccn(CCc3ccccn3)n2)c(C)s1 +c1cnn(-c2cc(-c3ccc4[nH]ccc4c3)ncn2)c1 +COc1ccc(C(C#N)CC(=O)N2CCCCC2)cc1F +CCN(Cc1ccc(OC)cc1)C(=O)c1cccc(C)c1O +O=C(Nc1c(F)cccc1F)N1CCC(Oc2cccnc2)CC1 +N#CC1C(=O)N=C(N2CCC(C(N)=O)CC2)NC12CCCC2 +CCOc1ccc(NC(=O)NCCc2c(C)nn(CC)c2C)cc1 +Cc1cc2cc(C(=O)N3CCCC3c3cccnc3)ccc2o1 +CNC(=O)NCC(=O)NCCc1nc(-c2cccc(Cl)c2)no1 +CCC(=O)Nc1ccc(C)c(NC(=O)c2ccc(OC)c(F)c2)c1 +CC(=O)Nc1ccccc1OCC(=O)Nc1ccc(F)cc1 +C=CCCCN(C)C(=O)CNC(=O)c1ccccc1C +Cn1nnnc1SCc1ccccc1Oc1cccnc1 +Cc1nnc(NC(=O)c2ccc(N3CCOCC3)cc2)s1 +O=C(Cc1ccon1)N1CCC(OCc2ccc(F)cc2)CC1 +Cc1cccc(C(=O)NCC(=O)Nc2cc(C)ccc2F)c1 +Cc1ccc(Cl)c(S(=O)(=O)N(C)C2(C#N)CCOC2)c1 +Cn1cc(CCC(=O)N2CCN(c3nccs3)CC2)cn1 +Cc1nc2ccc(C(=O)NC3CCCCC3)cc2s1 +Cc1cccc(NC(=O)c2cc3c(s2)CCC3)c1C(N)=O +COc1ncccc1NC(=O)C(C)Oc1ccccc1C#N +O=C(NCc1cc(-c2ccccc2)no1)c1cnns1 +CN1CCCN(C(=O)c2ccc(NC(N)=O)cc2)c2cc(F)ccc21 +COc1ccc(CN(C)C(=O)Cn2cnc(C#N)n2)cc1 +O=C1Nc2ccc(O)cc2Oc2ccc(Cl)cc21 +CCCN(CCO)C(=O)NC1CCN(c2cccc(Cl)c2)C1 +CC(C)Cn1c(CCCNC(=O)c2ccccn2)nc2ccccc21 +Nc1cc(C(F)(F)F)ccc1N1CCN(C(=O)c2ccccc2)CC1 +O=C(COc1ccc(C(F)(F)F)cc1)Nc1ccsc1 +COCc1cc(=O)[nH]c(NCc2ccc(F)cc2Cl)n1 +Cc1cccc2nc(C(=O)NC3C4CCOC4C3(C)C)cn12 +CCN(Cc1ccccc1NC(=O)NC(C)c1ccncc1)C(C)=O +O=C(NCCCNC(=O)c1cccc(Cl)c1)c1cccc(O)c1 +CCOC(C)c1noc(CNc2ccccc2F)n1 +COc1ccc(-n2c(SC(C)C#N)nnc2-c2ccncc2)cc1 +Cc1ccc(C(=O)N(C)c2ccccc2S(C)(=O)=O)cc1Cl +CCc1ccsc1C(=O)Nc1cccc(-c2nnco2)c1 +O=C1COc2cccc(OCc3csc(-c4cccs4)n3)c2N1 +Cc1csc(CCNC(=O)NC(C)Cn2cccn2)n1 +O=C(Nc1ccc2c(c1)COC2)N1CCN(c2cnccn2)CC1 +Cc1c(C(=O)OC(C)C)cnc2nc(SCC#N)nn12 +Cc1cc(C(=O)N2CCCC(c3cc(C(N)=O)[nH]n3)C2)c(C)s1 +Cc1n[nH]c(C(=O)NCc2cccc3c2OCO3)c1Br +COC(=O)Cc1nc2sc(C)c(C)c2c(=O)[nH]1 +Cn1cccc1CNC(=O)NCc1ccc(Cn2cccn2)cc1 +Cn1c(=O)[nH]cc(C(=O)N2CCc3ccccc3C2)c1=O +CC(C)C1(O)CN(C(=O)c2n[nH]c3c2CCC3)CC1C +CCOC(=O)c1cnn(-c2nc(C)cc(C)n2)c1NC(=O)C(C)C +CC(=O)NC(C)C1NCCc2ccc(C(F)(F)F)cc21 +CCCOC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +COC(CNC(=O)NC(C)C)c1ccc(C)s1 +CCc1onc(C)c1NC(=O)C(NC(=O)N1CCCC1)C(C)CC +COC(=O)C1(N(C)C(=O)Cc2n[nH]c3ccccc23)CCCCC1 +CCn1cc(C(=O)N(C)Cc2c(C)noc2C)cn1 +Cc1cc(NC(=O)CSc2nc(C(C)C)n[nH]2)no1 +COC(=O)Cn1ncc(N2CCCCC2)c(Cl)c1=O +N#Cc1ccc(C(=O)N2CCC3(CC2)C(=O)Nc2ccccc23)cn1 +Cc1c(CNc2ccc(N(C)C(C)C)c(F)c2)cc(C#N)n1C +COCCNC(=O)C1CC2C(CCN2Cc2ccc(C)s2)O1 +CCC(=O)Nc1cc(NC(=O)c2ccccc2F)ccc1C +NC(=O)Nc1ccc(NC(=O)c2ccn(-c3ccccc3)n2)cc1 +COc1cccc(NC(=O)C2Cc3ccccc3CN2C(C)=O)c1 +CCc1ccsc1C(=O)NCC(=O)NCC(F)(F)F +COC1CCCN(C(=O)c2cc(-c3ccccc3F)on2)C1 +Cn1nc2n(c1=O)CCN(C(=O)Nc1ccc(C#N)c(Cl)c1)C2 +CC(C(=O)NCc1ccccc1Cl)n1ncccc1=O +Cc1ccc(F)cc1NC(=O)c1cc(Cl)ccc1N +OCCNc1ncnc2ccc(-c3cc[nH]n3)cc12 +Cc1nc(CN(C)C(=O)c2nn(C)c(=O)c3ccccc23)cs1 +CC(C)NC(=O)N1CCSc2ccc(N)cc21 +Cc1ccccc1CN1CCn2ncc(C(=O)NCC3CC3)c2C1 +Cc1csc(C(C)(C)NCC(=O)NC(c2ccccc2)C2CC2)n1 +Cc1cccc(C(=O)N(C)Cc2nc(-c3cccs3)no2)c1 +Cc1nc(S(=O)(=O)NCCC(=O)NC2CCCC(C)C2)cn1C +O=C(c1cc(Cl)cc(Cl)c1)N1CCCC1C1=NC=CC1 +CC(C)n1nc(CN2CCCC2=O)c2c1CN(C(=O)c1ccc[nH]1)C2 +O=C(NC1CC1)c1ccc(NC(=O)c2csc3c2CCCO3)cc1 +O=C(N1CCCC(O)(CO)C1)C1(c2ccccc2)CCCC1 +O=C(CCc1cccc(F)c1F)N1CCN(C2CCCC2O)CC1 +CCC(CO)(CO)NC(=O)c1cc(C(F)(F)F)ccc1F +CS(=O)c1cccc(NCc2ccc(OC(F)F)c(F)c2)c1 +CCc1c(C(=O)CN2CCN(CC(F)F)CC2)[nH]c(C)c1C(C)=O +CC(C)c1ccccc1NC(=O)Cn1cnc(N)n1 +O=C(Oc1cccc(-n2cccn2)c1)c1cnc(C2CCCO2)s1 +COc1ccsc1C(=O)NCC(C)Oc1ccccc1 +CCc1ccc(CNCc2cccnc2-n2ccnc2)o1 +CCN(Cc1nccn1Cc1ccccc1C)C(=O)C1CCCC1 +CN(C)C(=O)COc1cccc(CNC(=O)Cc2ccc[nH]2)c1 +O=C1c2ccccc2NC2(C(=O)Nc3ccc(Cl)cc32)N1C1CC1 +COc1ccc(C(=O)N2CCN(Cc3ccccc3F)CC2)c(O)c1 +CCC(=O)N(C)CCc1noc(-c2cc3ccccc3[nH]2)n1 +CCc1nn2c(CNC(=O)c3cccnc3SC)c(C)nc2s1 +N#Cc1nnn(-c2ccc(Br)cc2)c1C1CC1 +NC(=O)c1n[nH]c2ccc(NC3CCOCC3)cc12 +C=CCOCC12CCCOC1CCN(C(=O)c1cc(C)[nH]c1C)C2 +O=C(COc1ccc(Cl)cc1)Nc1ccc(-n2ccnc2)cc1 +CN(CCCNC(=O)c1ccc2c(c1)CCC(=O)N2)S(C)(=O)=O +CC(C)CC1COCCN1C(=O)CCCc1cccs1 +COC1CCCC1OC(=O)c1cc(F)ccc1F +N#Cc1cccc(CN2C(=O)C(=O)c3ccc(Br)cc32)c1 +C#CCN1CCN(C(=O)NC2CC2c2c(F)cccc2Cl)CC1 +O=C(Nc1cccc(C(F)(F)F)c1)c1cc(Cl)c[nH]1 +CC(C)NC(=O)N1CCC2(CCC(=O)N2Cc2ccncc2)CC1 +Cc1ccc(-n2nnc3c(=O)n(CC(N)=O)cnc32)cc1Cl +CC(=O)Nc1ccc(NC2C(=O)Nc3ccc(F)cc32)cc1 +O=C(Nc1cc(F)c(F)c(F)c1)c1cnc(C2CCCO2)s1 +Cc1nnc(SCC#CCOC(=O)c2ccco2)s1 +CC(C)OC(=O)c1c(NC(=O)c2cnccn2)sc2c1CCCC2 +COc1ccc(C)cc1NC(=O)N1CCN(C(=O)CCC(C)C)CC1 +O=C(Cc1ccc(F)cc1)Nc1cnn(CC(F)(F)F)c1 +Cc1sc(NC(=O)C2CCOCC2)nc1-c1ccc(F)cc1 +CCOc1ncccc1CNC(=O)Nc1ccc(F)c(F)c1 +CN1Cc2cccc(N)c2C2(CCOCC2)S1(=O)=O +COc1ccc(-n2cccc2-c2c(C#N)c(N)nc3c2CNCC3)cc1 +Cc1ccn2c(=NC(=O)c3ccc4c(c3)NC(=O)CS4)[nH]nc2c1 +Cc1cc(Br)c2c(c1)N(C)C(=O)C(C(C)C)O2 +CCOC(=O)C1CCN(c2ncnc(N)c2N)CC1 +CCN1CCN(C(=O)c2[nH]ncc2Br)CC1 +CCc1ccccc1Cn1c(=O)oc2cccnc21 +CC(=O)Nc1cccc(C(=O)Nc2nc(-c3ccccc3)cs2)c1 +CCN(CCNc1ncc(F)cn1)C(=O)OC(C)(C)C +CC1CCc2c(F)cccc2C1NC(=O)c1n[nH]c(=O)[nH]1 +COc1ccc(NC(=O)COc2cccc3[nH]ccc23)c(OC)c1 +CC(C)OC(=O)CCNC(=O)NCc1ccco1 +Cc1nnc(CN2CCC(c3cccc(Oc4ccccc4)c3)C2)o1 +COc1cc(C(=O)N2CCN(C)CC2c2ccccc2)ccc1C +CCOC(=O)c1nnc(Cc2cccc(C(F)(F)F)c2)o1 +CC1CCCCC1NC(=O)CNc1ccccc1C(=O)NCCO +CC(=O)c1ccccc1C(=O)N1CC=C(c2ccccc2Cl)CC1 +CC(=O)c1cc(C(=O)Nc2ccc(Cl)cc2)n(C)c1 +CC(=O)NCC(=O)NC(C#N)c1cccc(Cl)c1Cl +O=C(c1cc(Cl)cc(Cl)c1)N1CCCCC1 +CC(C)(C)OC(=O)N1CCN(c2ccc(C(F)(F)F)cc2N)CC1 +CC(=O)NC(CC(=O)NC(C)c1cc(C)sc1C)c1ccccc1 +COc1ccc(S(N)(=O)=O)cc1C(=O)Nc1cc(C)ccn1 +CCCCn1nnc(NC(=O)COc2cc(C)c(Cl)c(C)c2)n1 +O=C(CCc1ccco1)NCCc1nc(-c2cccnc2)n[nH]1 +COCCNc1ncnc(NC23CC4CC(CC(C4)C2)C3)c1N +NC(=O)CNC(=O)c1cccc(NC(=O)Cc2cccc(F)c2F)c1 +O=C(Cc1cn2ccsc2n1)Nc1ccc(Cl)c(F)c1 +CC(C)C(=O)Nc1cccc(C(=O)NCc2ccccc2)c1 +OC(Cc1ccc(C(F)(F)F)cc1)Cn1cnnc1 +CSc1ccccc1C(=O)Nc1c(C(N)=O)oc2ccccc12 +O=C(NCCCc1ccco1)c1c(O)cccc1O +Cn1cc(S(=O)(=O)NCCC2CCCC2)cn1 +Cc1cc(CN2CCN(C(=O)Nc3cccnc3)CC2)on1 +CCOc1cc(C(=O)NCc2ccccc2C)ccc1OC +CC(c1ccccc1F)S(=O)(=O)c1nncn1C1CC1 +COc1cccc(C(=O)CNc2ccc(C#N)cc2)c1 +O=C(CNc1ccccc1N1CCCC1=O)NCCC1=CCCCC1 +COC(=O)c1ccc(NC(=O)c2cccc(OC)c2F)cc1Cl +Cc1nn(C)c2ncc(C(=O)N(C)C3CCCC3)cc12 +CC(Oc1ccccc1)C(=O)N(C)Cc1ccccc1 +CCOc1ccc(C(=O)C2CCCN2C(=O)CC)cc1 +CNC(=O)CN1C(=O)CNc2cc(Cl)c(Cl)cc21 +Cc1csc(C(NC(=O)CCNC(=O)C(C)(C)C)C2CC2)n1 +CCOc1ccccc1NC(=O)CCCn1cccc1 +Cn1cnc(CNC(=O)NCCc2cnn(-c3ccccc3)c2)n1 +COc1ccccc1C1CCCN1c1cc(C)nc(N)n1 +O=C(CNC(=O)C1CC1)NCc1ccc(Br)cc1Cl +COCCN(c1ncc(Br)cc1N)C(C)COC +COc1ccc(CS(=O)(=O)c2ccc(N)cc2)c(OC)c1 +CC(=O)N1CCc2cc(NCc3cnn(C)c3)ccc21 +CNc1snc(C)c1C(=O)Nc1cccc(SC)c1 +CCCc1nnnn1CC(=O)NCc1cccc(C)c1 +Cc1cc(NC(=O)C(C)C)nn1Cc1ccccc1 +CC(=O)Nc1ccc(S(=O)(=O)N(C)c2ccc(O)cc2)cc1 +Cc1noc(C)c1C(C#N)Cc1cccc(C#N)c1 +CNC(=O)c1cccc(C(=O)NCC2(CCOC)CCCC2)c1 +Cc1cc2occ(CC(=O)NC3CCc4nnc(C)n4C3)c2cc1C +N#Cc1ccc(F)c(C2NCCc3c(O)ccc(F)c32)c1 +COCC(=O)NC(Cc1ccccc1)c1sccc1C +NC(C(=O)Nc1cccc(Br)c1)c1ccccc1 +CSc1ccc(CN(C(=O)C(N)c2ccccc2)C2CC2)cc1 +C=CCn1c(C)nnc1SCC(=O)NCc1ccccc1F +CC(=O)N1CCCc2sc(C(=O)NCCc3ccccn3)nc21 +CN(CC(=O)NC(C)(C)C)C(=O)c1ccc(Oc2ccccc2)cc1 +Cc1ccc(-n2ccnc2SCCC(N)=O)c(C)c1 +COCCN(Cc1cnn(C)c1)C(=O)Nc1ccc(F)c(F)c1F +O=C1NCC(C(=O)N2CCC(c3nc4cc(Cl)ccc4o3)CC2)N1 +C=CCCC(=O)OC(c1ccncc1)c1ccc(F)cc1 +O=C(CNc1cccc(Cl)c1-n1cccn1)N1CCCCC1 +C=CCOc1ccc(CNc2cnn(-c3ncccn3)c2)cc1Cl +CC(NC(=O)Nc1ccc2c(c1)COC2)c1ccncc1 +CN(Cc1nc(-c2cccs2)no1)C(=O)c1ccccc1Cl +O=C(CN1CCCCCC1=O)NCCOc1ccccc1 +Cc1cc2c(cnc3ncnn32)c(=O)n1-c1ccccc1C(F)(F)F +CCNC(=O)CN(CC)C(=O)Cn1ncc2ccccc2c1=O +CCCn1c(O)nnc1SC(C)C(=O)Nc1cc(F)ccc1C +CCC(Oc1ccccc1F)C(=O)N1CC(=O)Nc2ccccc21 +O=C(CCCNC(=O)c1cccs1)Nc1ccc(Cl)cc1F +CCNS(=O)(=O)c1ccccc1NCC(=O)NC +CC(Sc1nnnn1C1CC1)C(=O)OC1CCCC1 +O=C(Cc1coc(-c2ccccc2)n1)Nn1cnc2ccccc2c1=O +Cc1cccc(Cn2ncnc2C2CN(C)c3ccccc3O2)c1 +Cc1n[nH]c2ncc(NC(=O)Cn3cc(C)c4ccccc43)cc12 +N#Cc1ccc(OCC(=O)Nc2ccc(N3CCOCC3)cn2)cc1 +Cc1nc(C(C)(C)Br)sc1CCO +CCc1nnc(N2C(=O)c3ccccc3C2(O)c2ccccc2)s1 +COc1ccc(-c2nnc3c(N)ccc(C)n23)cc1 +O=C(Cn1nc2n(c1=O)CCCCC2)OCC=Cc1ccccc1 +Cc1c(C(=O)Nc2cccc(Br)c2)cnn1C +CCN(CC)C(=O)CCC(=O)Nc1cccc(N2CCCNC2=O)c1 +Cc1nc(C)n(CC2CCCN2c2ncccc2C#N)n1 +CCN1C(=O)Nc2c(Cl)cccc2S1(=O)=O +COC(=O)CCNC(=O)Nc1cc(F)ccc1OC +CC(=O)c1ccc2c(ccn2C(=O)OC(C)(C)C)c1 +Cc1nnnn1-c1ccc(C(=O)NCCC(C)C)cc1 +COC(=O)c1ccc(NC(=O)c2ccc(N)cc2Cl)cc1 +COc1ccc(CCC(=O)Nc2cc(C)ccn2)cc1OC +Cc1ccoc1C(=O)N1CCNCC1C(=O)Nc1ccc(F)cc1 +N#Cc1ccc(OC(=O)c2cccc(OCC(F)F)n2)cc1 +Cc1cc(-c2nc3ccccc3o2)ccc1-n1cnnc1 +COc1ccc(OCCc2ncc(C(C)(C)O)s2)cc1 +O=C(Nc1ccccc1)c1nn(-c2ccccc2)c2c1CCC2 +COc1cccc(C(C#N)N(C)C(=O)c2ccccc2)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)Cc1ccccc1F +Cc1ccc(O)c(C(=O)Nc2ccc(N(C)C)nc2)c1 +Nc1ncnc(SCC(=O)NCc2cccs2)n1 +CC(Oc1ccc(F)c(F)c1)C(=O)NCc1ccsc1 +CN1CCC(N(C)C(=O)CN2CCCOC2=O)C1=O +CC(Oc1ccccc1)C(=O)Nc1ccccc1C(N)=O +COCC(C)N(C)S(=O)(=O)c1ccc(OC)c(N)c1 +COc1ccc(NC(=O)Nc2cc(F)ccc2F)cc1 +Cn1ccc2ccc(C(=O)NCCCn3ccnn3)cc21 +COc1ccc(N2CCn3c2nnc(C(=O)NCCCO)c3=O)cc1 +CCNc1ncc(C(=O)NCc2nc(C)sc2C)s1 +CCOc1cc(F)ccc1NS(=O)(=O)c1ccc(C)s1 +CC1CN(CCCn2c(=O)[nH]c3ccccc3c2=O)CC(C)O1 +COC(=O)c1ccc(S(=O)(=O)Nc2ccc(C)c(Cl)c2)o1 +NC(=O)C(c1ccc(F)cc1)N1CCN(c2ccccc2O)CC1 +COc1cc(C(=O)Nc2cc(Cl)ccc2C)on1 +O=C1COc2cc(C(=O)c3ccco3)c(Br)cc2N1 +COC(=O)c1cc(NC(=O)Cc2ccc[nH]2)ccc1C +C=CCOC(=O)C(C)NS(=O)(=O)c1cccs1 +CCc1nc2c(NC(=O)c3ccc(F)c(F)c3)cccn2n1 +CC(O)CN(CCO)S(=O)(=O)c1ccc(Cl)cc1 +Cc1csc(NC(=O)Cn2ncc3c2c(C)nn3C(C)C)n1 +CC(=O)N1CCN(c2ccccc2NC(=O)Cc2ccccc2)CC1 +N#Cc1ccc(-n2ccc(NC(=O)COc3ccccc3)n2)cc1 +O=C(NCc1cccnc1)c1n[nH]c2c1CCCC2 +N#Cc1cccc(OCC(=O)N(Cc2ccncc2)C2CC2)c1 +CC(=O)Nc1ccc(CN2CCOC3(CCc4ccccc43)C2)cc1 +CC(C)(C)C(=O)N(Cc1ccsc1)Cc1ccccn1 +COc1ccc(Nc2ncc(Br)cn2)cc1OC +Cc1c(Cl)cccc1CC1Oc2cc(N)ccc2NC1=O +CC(C)(C)C(O)CCNC(=O)Nc1ccccc1F +CS(=O)(=O)N1CC(C(=O)Nc2ccccc2)C2(CCCCC2)C1 +CCCN(CC1CC1)C(=O)c1cc(Cn2cnc3ccccc32)[nH]n1 +Oc1ccc2c(c1Cl)C(c1ccncc1F)NCC2 +CC(=O)Nc1ccc(C(=O)NC2CCCC2)cc1F +CCn1nc(C)cc1NC(=O)C(C)Oc1ccccc1Cl +CCC1CCCN(C(=O)CCC2Cc3ccccc3NC2=O)C1 +Cc1cc(=O)[nH]c(SC(C)C(=O)Nc2ccccc2Cl)n1 +Cc1cc(Cl)ccc1NCC(O)c1ccccn1 +CS(=O)(=O)c1ccc(NC(=O)c2ccccc2OC(F)F)cn1 +CNC(C)C1NCCc2cc(Br)c(OC)cc21 +COC(=O)c1cccc(NC(=O)CSc2nc(C)cc(=O)[nH]2)c1 +CCOC(=O)COC(=O)c1nn(-c2ccc(C)cc2)c2c1CCC2 +O=C(c1scnc1C1CC1)N1CCc2ccccc2CC1 +O=C(Cc1cn2ccsc2n1)Nc1cccc(-n2cnnc2)c1 +O=C(Nc1cccc(F)c1F)N(Cc1ccncc1)C1CC1 +CCn1ccc2ccc(NC(=O)c3ccc(-c4nnc(C)o4)cc3)cc21 +CC(=O)N1CCN(C(=O)c2cc(-c3ccccc3Cl)on2)CC1 +N#Cc1csc(C(=O)N2CCC3(CCCCC3)C2)c1 +Cc1occc1C(=O)Nc1ccccc1-n1cnnn1 +CN(C(=O)Cn1cnc2c(nnn2C)c1=O)c1ccccc1 +Cc1cccc(C)c1OCC(=O)NCCN1CCOCC1 +CC1CCN(C(=O)c2cc(NC(=O)C3CCCCC3)n(C)n2)CC1 +Fc1ccc(NCCCOCC(F)(F)F)c(F)c1 +COCCN1C(=O)Cc2ccccc2C1C(=O)N1CCCCC1 +O=C(NCc1nnc2ccccn12)c1ccc(Cl)c2cccnc12 +O=C(COc1ccccc1)NCC1Cc2cc(F)ccc2O1 +COc1cc(CNc2ccc(F)cc2C)cc2c1OCO2 +Cn1cc(-c2nc(C3CCCCCN3C(=O)C3CCCC3)no2)cn1 +Cc1ccc(NC(=O)Cn2cnc3sc4c(c3c2=O)CCC4)cc1 +CCCCS(=O)(=O)NC(C#N)c1ccc(OC)cc1 +COc1cc2nc(-c3cccc(N)c3)n(CC(C)C)c2cc1OC +CCOc1ncccc1C(=O)Nc1ccn(CCc2ccccn2)n1 +Cc1noc(NC(=O)CC(C)c2ccc(F)cc2)n1 +O=C(NCC(F)(F)F)c1ccc(CSc2ncn[nH]2)cc1 +Cc1ccc(-c2ccc(CO)c(=O)n2CC(C)C)cc1 +COC(=O)CCCS(=O)(=O)Nc1cccc(C)c1 +CC(CS(=O)(=O)c1ccc(F)cc1)C(=O)NCc1cc[nH]n1 +O=C(c1ccc(Br)cc1)N1CCN(Cc2cc[nH]n2)CC1 +CC(Cc1ccccc1F)NC(=O)CCn1cnc2ccccc21 +Cc1cccn2cc(CNC(=O)c3c(F)cccc3F)nc12 +Cn1cc(C(=O)Nc2ccc(-n3ccnc3)c(F)c2)ccc1=O +O=C(C1CC2C=CC1C2)N(CCO)Cc1cccs1 +O=C(c1ccncc1)N1CCN(CC(O)c2ccccc2F)CC1 +Cc1cccc(C(N)=O)c1NCC#Cc1ccc(C(F)(F)F)cc1 +O=C(NC1CCCCC1)c1c(O)nc2ccccn2c1=O +N#Cc1nc(C=Cc2ccccc2)oc1NCC1CCCO1 +NC(=O)c1ccc(C#CCNC(=O)Nc2cccs2)cc1 +Cc1cccc(CNC(=O)c2ccc(F)cc2N)c1 +Cc1ccsc1-c1nnc(CC(=O)NCCC2=CCCCC2)o1 +COC(=O)c1ccc(-n2nc(C)c(Br)c2C)cc1 +CC1CN(Cc2ccco2)CCN1C(=O)c1nccc2ccccc12 +CCOc1ccc(CNC(=O)C2CCCC2)cc1F +Cc1cccc2c1N(C(=O)c1ccoc1C)CCC2 +CN(C(=O)C1C2CC3OC(=O)C1C3C2)c1ccccc1Cl +Cn1ccn2ncc(C(=O)NCCc3ccc(S(N)(=O)=O)cc3)c12 +COc1ccccc1CCN(C)Cc1c(C)nn(C)c1OC +CC(=O)Nc1cc2nn(-c3ccc(Cl)cc3)nc2cc1C +O=C(CNS(=O)(=O)Cc1ccc(F)cc1)NC1CCCCC1 +Cc1nn(Cc2ccccc2Cl)c(=O)c2noc(C)c12 +CC(C)C(NC(=O)c1ccnc2ncccc12)C(=O)NC1CC1 +Cc1ccc2c(=O)n(CCN3CCNC3=O)cnc2c1 +COc1cc2ccccc2cc1-c1nn2c(C)nnc2s1 +Cc1cc(C)n(C(C)C(=O)N(CCC#N)c2ccccc2)n1 +NC(=O)c1ccc2c(c1)CCCN2C(=O)CCC(F)(F)F +Cc1c(C(C)NC(=O)c2ccc(-c3ccccc3)[nH]c2=O)cnn1C +CCc1nc2scc(-c3ccc(F)cc3)c2c(=O)n1CC#N +O=c1c(Cl)c(Cl)cnn1Cc1cc(=O)n2ccsc2n1 +C#CCOc1ccc(NC(=O)N(C)Cc2noc(C)n2)cc1 +Nc1nc(CS(=O)(=O)c2ccccc2)cc(=O)[nH]1 +CC(C)(O)CN1CCN(C(=O)C2CCCCC2C(F)(F)F)CC1 +COC(=O)C(C)Sc1nnc(-c2ccc(C)cc2)n1C +Cc1cc(=O)[nH]c(C2CCN(C(=O)CO)CC2)n1 +Cc1ccc(C(=O)Nc2cc(S(C)(=O)=O)ccc2Cl)cc1C +O=C(c1ccccn1)N1CCc2onc(Nc3cccc(F)c3)c2C1 +O=C(COC(=O)c1ccncc1)Nc1ccccc1-c1ccccc1 +Cn1cnnc1C1CCCN(C(=O)c2cn[nH]c2)C1 +COc1ccccc1NC(=O)CNC(=O)c1cc2cccnn2c1 +CCOc1ncccc1CNC(=O)CCc1ccsc1 +Cc1cnc(C(C)(C)NC(=O)c2ccnc(OC3CCC3)c2)s1 +CN(C)C(=O)c1cccc(NC(=O)CCc2ccccc2Cl)c1 +CNc1snc(C)c1C(=O)Nc1cccc(OCC(F)(F)F)c1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(C(F)(F)F)cc1 +O=C(NCc1ccc(F)c(Cl)c1)c1cccs1 +Cc1csc(NC(=O)c2cncn2-c2ccc(F)cc2)n1 +O=C(CCCc1ccccc1)OCC(=O)N1CCOCC1 +CC(C)N(C)C(=O)NCc1ccccc1OCCN1CCOCC1 +Cc1ccc(S(=O)(=O)NCC(=O)N2CCc3ccccc32)cc1 +Cc1nc(C2(NC(=O)c3cnn[nH]3)CCCCC2)no1 +CC(C)(C)c1nc2cc(NC(=O)Cn3ccc(=O)[nH]c3=O)ccc2o1 +Nc1cc(CCC(=O)N2CCOCC2)ccc1O +COc1cccc(-c2nnn(CC(=O)N(C3CC3)C(C)C3CC3)n2)c1 +O=C(Cc1ccc(F)cc1F)OCC(=O)N1CCc2ccccc21 +Cc1cc(C(=O)OCCOc2ccc(S(N)(=O)=O)cc2)c(C)o1 +O=C(Cc1noc2ccccc12)NCc1cccc(OC(F)F)c1 +COCC(C)N1CCN(C(=O)C(C)Oc2ccc(Cl)cc2)CC1 +COC(=O)c1ccc(C(F)(F)F)c2c1CC(=O)N2 +O=C(Cc1cccc(C(F)(F)F)c1)NCc1cccs1 +CCN(C)c1ccc(C(=O)Nc2ncc(C)s2)cc1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)OCc1cccnc1 +Cc1cc(C(=O)N2CCC(C(O)c3ccccc3)CC2)c(C)o1 +Cc1noc(C)c1C(C)NC(=O)c1cccc2c1OCCO2 +Cc1nc(CCNC(=O)Cc2cccc(OCC#N)c2)sc1C +CNC(=O)c1c(-c2ccc(F)cc2)nc2n1CCS2(=O)=O +Nc1ccccc1NC(=O)CCCSc1ccccc1 +CC(C)CN(CC(N)=O)c1nc2sccn2c1CO +CN(C)c1c(Cl)cccc1NCC1CCC=CO1 +Cc1cc(NC(=O)c2ccc(C)n2C)n(CCC#N)n1 +CCC1CCC(NC(=O)c2ccc(OC)c(OC)c2)CC1 +Cc1ccc(Cl)cc1N1CCN(C(C)C(=O)NC2CC2)CC1 +CC(=O)Nc1ccc(SCc2ccccn2)nn1 +O=C(c1ccc[nH]c1=O)N1CCCC1C1CCCC1 +O=C(NCC1CCC2C1OCCN2c1ncccn1)c1cnccn1 +O=C(Cc1ccc[nH]1)N1CCC(C(O)c2ccc(Cl)cc2)CC1 +COC1COC2C1OCC2n1nnnc1Sc1ncccn1 +CCOc1cc(CNC(=O)c2cccnc2OC)ccn1 +CC(=O)Nc1ccc(-c2nc3sc(C4CC4)nn3c2C#N)cc1 +Cc1ccc2c(CC(=O)NC(C)c3cnn(C)c3C)coc2c1 +COc1cc(CNc2ccc(C#N)cc2)c2c(c1)CC(C)O2 +Cc1ccc(-c2nc(-c3ccncc3)no2)c(Cl)c1 +CCOc1ccc(C(=O)Nc2n[nH]c(-c3ccco3)n2)cc1OC +O=C(NCCOC(=O)C1CC2CCC1C2)c1ccncc1 +Cc1c(C(=O)NC(C)C(C)(C)c2ccccc2)cnn1-c1ccncc1 +CC(=O)Nc1cc(C(=O)NCCOc2cccc(F)c2)ccc1C +O=C(NCC1(c2ccccc2)CCCC1)c1n[nH]c(=O)[nH]1 +Cc1nnc(SCC(=O)N(Cc2ccccc2)C(C)C)n(N)c1=O +N#Cc1ccc(NCC(=O)N2CCC(c3ccc(O)cc3)CC2)cc1 +CC(C)c1cc(NCC(O)CO)n2nccc2n1 +O=C(Nc1ccc2c(c1)OCO2)c1cc2n(n1)CCS2 +Cn1cccc1C(=O)N(Cc1cccnc1)CC1CCCO1 +C=CCN1C(=O)C(C(C)C)Oc2c(OC)cc(CO)cc21 +Nc1cccc(OCCNC(=O)Cc2c[nH]c3ccccc23)c1 +CNC(=O)C1(NC(=O)CNC(=O)C2CC2)CCCCC1 +Nc1ccccc1-c1nc2ccc(F)c(F)c2n1CCO +COc1cccc(C(=O)N2CCCC(c3cc(=O)cc(C)[nH]3)C2)c1 +Cc1nc(NCCc2ccncc2)c2ccsc2n1 +c1ccc(CCN2CC3OCCN(CC4CCCO4)C3C2)cc1 +CC(C)(C)c1ncc2c(n1)CN(c1ncc(C#N)c(N)n1)C2 +C=CCn1c(SCC(=O)OC)nnc1C(C)(C)C +O=C(Nc1ccc(SCc2ccccn2)nn1)c1ccco1 +COc1cccc(C(=O)NCCNC(C)=O)c1OC +COC(=O)CN1C(=O)CC(C)(C)S(=O)c2ccccc21 +O=C(OCc1nnc(-c2ccc(Cl)cc2)o1)c1ccncc1 +CCCNS(=O)(=O)c1ccc(NC(=O)N(C)C(C)CC#N)cc1 +CC(C)Cn1nccc1NC(=O)C(C)Oc1ccccc1C#N +O=S(=O)(NCCC(O)C1CC1)c1cccc(Cl)c1 +CCc1nnc(CN(C)c2ccc(F)c(F)c2)o1 +Cc1noc(C)c1CC(=O)N(CCO)C1CCCC1 +NC(=O)C1Cc2ccccc2N1C(=O)C1CC=CC1 +CCS(=O)(=O)NCC(=O)c1cc(C)c(OC)cc1C +Nc1cc(Cl)ccc1NC(=O)COCC1CCCO1 +O=C(Cc1ccc(F)cc1)Nc1cnc(-n2ccnc2)nc1 +CCN1C(=O)CCc2cc(NC(=O)Cc3ccc(Cl)cc3)ccc21 +Cc1ccc2oc(=O)c3cc(C(=O)N4CCN(C)CC4)sc3c2c1 +CCNC(=O)CSc1nc(=O)ccn1C(C)C +Nc1ccc(Cl)c(NC(=O)c2ccc(F)c(F)c2)c1 +CCOc1ccc(CCCNc2cccnc2)cc1N +CN(C)S(=O)(=O)N(C)Cc1sccc1Br +O=C(NC1CC1)c1ccn2c(-c3ccc(Cl)cc3)nnc2c1 +Cc1ccnc2nc(C(=O)NCCNC(=O)c3ccccc3)nn12 +COc1ccc(OC)c(CC(=O)NCCc2cccs2)c1 +O=C(NCCc1nc(-c2ccncc2)n[nH]1)c1c(F)cccc1F +CCc1nc(C(=O)Nc2ccc(C(C)=O)c(C)c2)c[nH]1 +COc1ccc(NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)cc1O +Cn1ccnc(NC(=O)C(C)(C)c2cccs2)c1=O +CS(=O)(=O)N1CCN(C(=O)c2ccn3ccsc23)CC1 +COc1ccccc1OCc1nc2ccc(CO)cc2o1 +Cn1c(=NC(=O)CCNC(=O)c2ccoc2)sc2ccccc21 +COC(=O)c1cc(-c2csc(NC(=O)CCn3cncn3)n2)c[nH]1 +NC(=O)N1CCCC(C(=O)Nc2cccc(C(F)(F)F)c2)C1 +CC(C)n1cc(C(=O)N2CCC2c2nc(-c3cccnc3)no2)cn1 +Cc1nc(C)c(C(=O)NCCOc2ccc(C(F)(F)F)cn2)o1 +Cc1ccc(C)c(C(N)c2cccn(CC(C)C)c2=O)c1 +CCOC(=O)N1CCC(NC(=O)Cc2c(F)cccc2F)CC1 +CCCN(CC1CC1)C(=O)NCc1ccnn1C +CC1(C)CN(C(=O)NCCc2cccs2)CCC1(C)O +Fc1cccc(F)c1CNc1ccc(Cl)cn1 +CCC1(C)CCCN(C(=O)c2cc(Cn3cc(C)cn3)on2)CC1 +Cc1nn(C)c2oc(N)c(C(=O)c3ccncc3)c12 +CCOC(=O)c1cnc(C)nc1N(C)Cc1ccccc1 +CCC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1 +CCOc1cccc(CCC(O)c2cccnc2)c1 +CCN(Cc1ccccc1)C(=O)c1cc(NC(N)=O)ccc1Cl +O=C(c1ccccc1)N1CCN(c2ccc(-n3ccnc3)nn2)CC1 +CC(=O)Nc1cccc(Nc2nc(=O)[nH]nc2C)c1 +COc1cc(NC(=O)Cn2nnc(-c3ccccc3)n2)cc(OC)c1 +COc1cccc(CC2(C(=O)N3CCC(O)C3)CC3CCC2C3)c1 +Cc1cc(C(=O)N(C)CC(=O)Nc2ccc(Cl)c(Cl)c2)no1 +CN(C)c1cccc(C(=O)Nc2cccnc2-n2cccn2)c1 +COCCOC(=O)c1cc(C(=O)Nc2ccccc2C)c(=O)[nH]c1C +CCN(CC)C(=O)CNC(c1ccccc1)c1ccccn1 +CCCC(=O)N(Cc1ccccc1)C(C)CN1CCOCC1 +CCOC(=O)CN1CCN(Cc2csc(C(C)(C)C)n2)CC1 +CCc1cc(NC(=O)N2CCc3cc(F)ccc3C2)n(C)n1 +CCCC1CN(C(=O)Cn2nccn2)CC1NS(C)(=O)=O +Cc1c(-c2nn3c(-c4cccs4)nnc3s2)cnn1C +COC(=O)C1(NC(=O)Cc2ccc(OC)cc2)CCCCC1 +COc1ccc(C(=O)NCC(=O)NCc2c(C)cc(C)cc2C)cc1 +Cc1ccccc1CNS(=O)(=O)N(C)CCC#N +CC(=O)N(C)C1CCN(C(=O)Nc2ccc(F)c(C#N)c2)CC1 +Cc1ccncc1NC(=O)N(C)C(C)c1ccccn1 +O=C(NCc1ccco1)NCc1cccn1Cc1ccc(F)cc1 +CCc1nc2n(n1)CCCC2NC(=O)c1ccc2c(c1)[nH]c(=O)n2C +Cc1cc(C)n(C(C)C(=O)c2ccc(F)c(F)c2)n1 +Cn1cc(CNc2ncc(Cc3cccc(F)c3)s2)cn1 +COCCC1NCCc2ccc(OC(F)F)c(OC)c21 +CN(Cc1c(F)cccc1Cl)C(=O)CSc1nncs1 +Cc1cc(C)c(C(=O)NCCCc2nc(C)cs2)c(C)c1 +CCOc1nnc(CN2CCN(c3nccs3)CC2)s1 +O=S(CCSc1nnnn1C1CCCC1)c1ccccc1 +CSc1ncnc(NCc2cccc(Cl)c2)c1C#N +N#Cc1ccc(Cn2nc(CO)cc2-c2ccccc2)cc1 +CCS(=O)(=O)N1CCN(C(=O)COc2cccc(C)c2)CC1 +CCCC1CCC(NC(=O)c2cc(C)on2)CC1 +Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CC(C)C +CCOc1ccccc1NC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +CCNC(=O)NC(C)Cc1ccc(Br)cc1 +N#CCc1ccc(NC(=O)NCc2ccc3c(c2)CCC3)cc1 +CCCS(=O)(=O)N1CCc2[nH]nc(-c3ccccc3F)c2C1 +Cc1ccc(CNS(=O)(=O)c2ccccc2F)c(N(C)C)c1 +COC(C)C(=O)Nc1cccc(NC(=O)c2cccc(N(C)C)c2)c1 +CC(C)(C)OC(=O)NCCC(=O)NC(C#N)c1cccc(Cl)c1 +O=C(CSc1nnnn1C1CC1)NC1CCCc2ccccc21 +CS(=O)(=O)N1CCCCC1C(=O)NCC(=O)NC1CC1 +CCCCNC(=O)C(C)N1CCN(C(C)C(=O)N2CCCC2)CC1 +Cc1nc[nH]c1-c1nccn1CCc1nc(C)c2c(n1)CCC2 +CS(=O)(=O)Nc1cccc(C(=O)NCC2CCCO2)c1 +CC(C)N(C(=O)CNc1ccn(CC(N)=O)n1)c1ccccc1 +COc1ccc(CCNC(=O)c2noc3c2CCCCC3)cc1OC +COc1cc(NC(=O)c2cccnc2OCC(F)F)cc(OC)c1 +Cc1ncc(CN2CCOC(c3ccco3)C2)n1-c1ccccc1 +CCCc1cc(C(=O)Nc2ccc(Cc3ccncc3)cc2)n(C)n1 +O=C(Cn1nnc(-c2ccco2)n1)NC1CCCC1 +CCc1onc(C)c1NC(=O)NCC1(CC(C)C)CCC1 +Cc1n[nH]c(C(=O)NCC(O)c2cccc(F)c2)c1Br +Cc1ccc(N(C(C)C(=O)N2CCCCC2)S(C)(=O)=O)cc1 +CCC(OC)C(=O)NC1CCCc2c1cnn2C +COc1ccc(NC(=O)c2sc(-c3ccccn3)nc2C)cc1 +CSc1nnc(SCc2cn3c(C)cccc3n2)s1 +N#Cc1cccnc1NCC1(N2CCOCC2)CCCCC1 +Cn1cc(C(N)=O)cc1C(=O)OCC(C#N)Cc1ccccc1 +O=c1c2c([nH]c3c(-c4ccncc4)cnn13)CCC2 +O=C(CCc1ccncc1)Nc1cccc(OCC2CCCO2)c1 +Cc1ccn2c(=NC(=O)Cn3nc4ccccn4c3=O)[nH]nc2c1 +CC(CC(=O)NCC1(CCO)CCOCC1)c1ccc(F)cc1 +CCCNC(=O)c1nnn(Cc2ccc(Cl)cc2)c1-n1cccc1 +O=C(c1cc2c(s1)CCC2)N1CCN(c2ccc(O)cc2)CC1 +Cc1ccc2c(c1)CC1(Cc3c(C)cccc3C1=O)C2=O +N#Cc1nc(-c2ccc(Cl)cc2)oc1NCCc1ccccn1 +CNc1nnc(-c2nnc3scc(C(F)(F)F)n23)s1 +CC1CCN(C(=O)C2CN(C(=O)c3ccc4c(c3)OCO4)C2)CC1 +Cc1cc(=O)n2nc(C(F)(F)F)nc2n1CC(O)c1ccccc1 +COc1cc(C)cc(C(=O)Nc2ccc3c(c2)COC3)c1O +NS(=O)(=O)c1ccc(CCNC(=O)C2CCC2)cc1 +Cc1cc(NC(=O)c2ccc3c(c2)nnn3C)ccc1C(=O)N(C)C +CN(CCc1noc(-c2ccc(F)cc2)n1)C(=O)Nc1ccccc1 +CC(C)(C)OC(=O)NCC(=O)N(Cc1ccc(Cl)cc1)C1CC1 +Cc1n[nH]c(C)c1NC(=O)CCCc1nc2ccccc2s1 +CCC(=O)Nc1nnc(SCc2cccc(F)c2)s1 +CC1Cc2ccccc2N1CC(O)c1cc(F)ccc1F +Cc1nn(C)c2ncc(NC(=O)NCc3ccoc3)cc12 +CS(=O)c1cccc(NC(=O)N2CCCC3CCCC32)c1 +CCCc1c(C(=O)N(C)Cc2cc(C)on2)[nH]c(C)c1C(C)=O +CCC(=O)NCCCn1nc(-c2cccs2)ccc1=O +CCc1nc2n(n1)CCCC2NC(=O)Cc1ccc(C)c(OC)c1 +COc1ccc(C(NC(=O)Cc2csc3nccn23)C2CC2)cc1 +CNC(=O)NCC(=O)NCCOc1c(C)cccc1C +CC(C)N(C(=O)c1cc(Cl)c2c(c1)OCO2)C1CC1 +Cn1cc(-c2nnc3sc(-c4ccc(Cl)cc4F)nn23)cn1 +CN(CC(O)C1CC1)C(=O)c1cc(Cl)ccc1O +O=C(NCCCN1CCCCCC1=O)c1cccc(Cl)c1 +Cc1cc(C)nc(SCC(=O)NCc2cc3ccccc3o2)n1 +CCNc1ccc(COc2cccc(F)c2F)cn1 +CC(C)CCNC(=O)CCCc1nc2ccccc2c(=O)[nH]1 +COc1cc(CNC(=O)N2CCOCC2)ccc1OCC(F)(F)F +Cc1ccc(F)c(S(=O)(=O)NCc2cn(-c3ccccc3)nn2)c1 +NC(=O)c1cccc(CNC(=O)NCCc2nc3ccccc3[nH]2)c1 +COc1ccc(NC(=O)NC2c3ccccc3CC2O)cc1C +CCc1cc(C(=O)Nc2cc(F)ccc2F)c2c(C)noc2n1 +Cc1ccnc(N(C)CC2CCCN(C(=O)OC(C)(C)C)C2)n1 +O=C(Nc1ccc(NC(=O)C2CC2)cc1)c1ccc(OC(F)F)cc1 +COc1ccc(S(=O)(=O)NC2CCCC2)cc1C(N)=O +CC1CN(C(=O)Cc2ccc(N3CCNC3=O)cc2)CCC1(C)O +O=C(c1cccc(S(=O)(=O)NC2CC2)c1)N1CC(n2ccnc2)C1 +Cc1cc(C(=O)OCC2CCCCO2)c2cnn(C(C)C)c2n1 +CCc1cc2c(=O)n(CC(=O)Nc3cccc(C#N)c3)cnc2s1 +CC(C)N(C)C(=O)NCCc1ccc(S(C)(=O)=O)cc1 +COc1ccc(OC)c(N2Cc3ccc(N)cc3C2)c1 +Cc1cc(Cl)ccc1S(=O)(=O)N1CCOCC1 +Cc1nc(CCCn2cncn2)n(-c2cccc(Cl)c2F)n1 +CC(NCC(=O)NCc1cccnc1)c1ccc2c(c1)CCC(=O)N2 +OC(Cn1nnnc1-c1ccccc1)Cn1nnnc1-c1ccccc1 +CCCCC(NC(N)=O)C(=O)N1CC(CC)C(N2CCOCC2)C1 +Cn1c(=O)oc2cc(NC(=O)NCCCOCC3CCOC3)ccc21 +CN(C)c1nnc(SCC(=O)c2cnn(C)c2)s1 +CCCCC(COC)NC(=O)Nc1ccc2c(c1)oc(=O)n2C +Cc1ccc(C(=O)C(C)Oc2ccccc2N)cc1 +Cc1ccccc1OCCCCS(=O)(=O)c1n[nH]c(N)n1 +OCCOCCNc1ncc(Br)c2ccc(F)cc12 +Cc1ccc(C(=O)NC(C#N)c2ccccn2)cc1 +COCCc1noc(CNc2ccc(C(=O)N(C)C)c(C)c2)n1 +Cc1ccc(C)c(OC(C)C(=O)N(C)C2CCCCC2O)c1 +Cn1nc2nc(N3CCCCC3)nc(-c3ccccc3F)c2c1N +CCC1(c2nc(-c3ccc(C#N)cn3)no2)CCCC1 +Cc1cc(C)c(NC(=O)c2ncccc2F)c(C)c1 +C=CCc1cc(C(=O)Nc2ccc(NC(C)=O)cc2)ccc1OC +O=C(CC1NC(=O)c2ccccc2N=C1O)Nc1ccc(Cl)cc1 +Cn1nnnc1SCCC(=O)NC(C1CC1)C1CC1 +Cc1cccc(OC(C)C(=O)NCc2ccccn2)c1 +CC(C)(C)CC(=O)Nc1nnc(-c2ccccn2)[nH]1 +COc1cccc(Cn2ncc3cc(N)ccc32)c1 +CC(C)CCOC(=O)CN1CCCOc2ccc(N)cc21 +CC1CN(S(=O)(=O)c2ccc(C(=O)N(C)C)cc2)CC(C)O1 +Cc1nn(C(C)C)c(C)c1CN(C)C(=O)C1COc2ccccc2C1 +Cc1cccc(NC(=O)CSc2nnc(-c3cccs3)n2N)c1 +CC(C)Oc1ccc(C(=O)N(CCC(N)=O)c2ccccc2)cn1 +Cc1nn(-c2ccc(Cl)cc2)c(C)c1S(=O)(=O)NC(C)C +N#CCCn1cc(-c2csc(N3CCCCC3)n2)c2ccccc21 +Cc1cccc(Cl)c1NC(=O)NC1(C)CCOCC1 +O=C(Cc1ccccc1)NCCC(=O)N1CCCC1 +Cc1nc2ccc(N)cn2c1CC(=O)NCc1cccnc1 +NC(=O)CN1C(=O)COC2CN(Cc3cnc4ccccc4c3)CC21 +Cc1cccc(OCc2cc(N)cc3c2OCOC3)c1 +Cn1ncc2c(=O)[nH]c(CN3CCCC3c3cccc(Cl)c3)nc21 +CCNC(=O)C(N)c1cccc(Br)c1 +CN(C)c1ccc(NC(=O)C(Cc2ccccc2)NC(N)=O)cn1 +COC(CNS(=O)(=O)c1ccc2ccccc2c1)c1ccsc1 +O=C(Cn1nc(-c2ccc(F)cc2)oc1=O)NCCc1cccs1 +CC(=O)Nc1ccc(NC(=O)NCc2ccoc2)cc1C +N#Cc1ncn(CCC(=O)Nc2cccc(Br)c2)c1C#N +O=C(Nc1ccc(-c2cnco2)cc1)c1ccc(O)c(Cl)c1 +Cn1cnc(-c2ccc(F)cc2)c1NC(=O)c1ccccc1F +Nc1cc(F)cc2c(C(=O)Nc3ccccn3)nccc12 +COc1ccc(CCC(=O)Nc2cccc(C#N)c2)cc1N +C#Cc1cccc(NC(=O)N2CCN(C(=O)OCC)CC2)c1 +NS(=O)(=O)c1ccc(CNC(=O)c2cccc3ncccc23)cc1 +O=C(CSc1nnc(-c2ccc3c(c2)OCO3)o1)N1CCCC1 +Cc1cc(C(=O)NCCNC(=O)C(C)C)c2c(C)noc2n1 +CCOc1cc(C(=O)Nc2ccc(F)cc2C)ccc1OC +CSc1cncc(N2CCC(C3CCOCC3)CC2)n1 +CCN(CC(O)c1ccc(C)cc1)C(=O)Nc1ccc2c(c1)COC2 +O=C(Nc1nccs1)C(Cc1ccccc1)n1cnnn1 +CC(=O)c1cc2cc(C(=O)NCCCc3ccccc3)cnc2[nH]1 +COCCn1c(Cn2nnc3ccccc32)cc(C)c1C +C#CCOCC1CCCN(C(=O)Cn2ccc3ccccc32)C1 +O=S(=O)(c1ccc(C(F)(F)F)cc1)N1Cc2cncnc2C1 +NC(=O)c1ccc(CNC(=O)Nc2nccs2)cc1 +Cc1csc(NC(=O)c2ccc3nc4c(nc3c2)C2CCC4C2)n1 +Cc1nn(Cc2ccc(F)cc2)c(C)c1NC(=O)c1ccnn1C +Cn1c(SCC(=O)Nc2nncs2)nnc1C1CC1 +COc1cc(F)c(-n2cnc(CCNC(C)=O)c2)cc1F +CC(Nc1cnn(CC2CCCO2)c1)c1nc2ccccc2o1 +Cc1cc(C)n2nc(SCC(=O)Nc3ccccc3F)nc2n1 +O=C(NCCOc1ccccc1Cl)NC1CCOC(C2CC2)C1 +CCOc1cc(NC(=O)c2scnc2C)ccc1OC +CC(c1ccc(Cl)cc1)N(C(=O)c1nccn2ccnc12)C1CC1 +COc1ccc(C(N)=O)c(OCC(=O)NC2(C#N)CCCCC2)c1 +CCOc1cc2c(cc1CNC(=O)Nc1ccn(C)n1)OC(C)C2 +CC(C)c1nc(NC(=O)NCc2ccc(OCC3CC3)nc2)n(C)n1 +O=C(CCC1CCCO1)N1CCC(O)(C(F)(F)F)CC1 +CCCn1nnnc1COc1ccc2c(c1)OCO2 +CCc1nnc2c(=O)n(-c3ccc(OC)cc3)ccn12 +COC(C)(C)c1noc(-c2cc3ccccc3c(=O)[nH]2)n1 +CCC(NC(=O)c1ccnc(OC2CCC2)c1)c1noc(C)n1 +CCOC(=O)C1CCN(C(=O)NCCOc2cccc(F)c2)CC1 +COc1ccc(OC)c(C(C)NC(=O)c2ccc(=O)n(C)n2)c1 +COc1ccc(C(O)CNCc2ccco2)cc1C(C)(C)C +Cn1c(C(=O)Nc2cccnc2)cc2ccc(F)cc21 +Cc1c(C#N)nnn1-c1ccc(Br)cc1 +Cc1cc(C)n(CC(=O)N2CCc3cc(F)ccc3C2)n1 +CC(OC(=O)c1ccc(-n2cncn2)cc1)c1ccc(F)cc1 +CS(=O)c1cccc(NC(=O)c2ccc(OC(F)(F)F)cc2)c1 +O=C1Nc2ccccc2NC1c1cccc(Cl)c1 +Cc1cc2nc(N(C)CC(N)=O)c3ccccc3n2n1 +CCOc1cccc(C(=O)NCCN2CCOCC2)c1 +COc1cccc(C2CCCN2C(=O)Nc2cccn(C)c2=O)c1 +COc1cc(OC)cc(C(=O)N2CCC(=O)CC2)c1 +COc1cccc(C(=O)NCC(c2cccn2C)N2CCOCC2)c1 +CC(=O)N1CCCC1C(=O)Nc1ccc(C)cc1F +N#Cc1cccc(CNS(=O)(=O)c2c(Cl)cccc2Cl)c1 +NC(=O)CCN(C(=O)C1CCOCC1)c1ccccc1 +COCCNC(=O)c1sc2ccc(F)cc2c1C +CC(O)c1ccccc1NC(=O)c1ccccc1Cl +COc1ccc(C(=O)NCCNc2cccc(F)c2C#N)cc1 +CC(=O)c1cnc(N2CCC3(CC2)COC(=O)O3)nc1C +CCNC(=O)c1ccc(NC(=O)NCc2cn(C)nc2CC)c(C)c1 +CCC(O)CN(Cc1ccccc1)S(=O)(=O)c1cnc(C)s1 +Cc1ccc(NC(=O)CCNS(=O)(=O)c2cccnc2)cc1C +Cc1cc2c(cc1C)OC(C(N)c1cccs1)CO2 +CC(C)COC(=O)C(C)NC1=NS(=O)(=O)c2ccccc21 +O=C(c1ccco1)N1CCCC(c2nnc(C(F)(F)F)o2)C1 +CCCC(=O)Nc1ccc2ncnc(N3CCCCC3)c2c1 +Cc1oc(C(=O)N(C(C)C)C(C)C)cc1S(=O)(=O)N(C)C +CC(NC(=O)c1ccc(-n2cccn2)cc1)c1nnc2ccccn12 +COc1cc(CNC(=O)NCC(=O)N2CCCC2)cc(OC)c1 +COc1cc(CNc2ccccn2)cc(Cl)c1O +Nc1cccc(C(=O)NCc2cccc3cc[nH]c23)c1 +Cc1ccc(S(=O)(=O)NCCC(=O)NCC2CCCO2)cc1C +CC(OC(=O)c1cccc(O)c1)C(=O)N1CCc2sccc2C1 +N#CCn1nc(-c2ccccc2Cl)c2c1CCNC2 +CCNC(=O)CN1CCN(C(=O)c2c[nH]c(=O)cn2)CC1 +CCn1nc(C)c(Cl)c1C(=O)Nc1ccc(C(=O)NC)cc1 +CSc1ccccc1NCc1cnn2ccccc12 +CC(C)NC(=O)c1ccc(NC(=O)c2cnn3ncccc23)cc1 +COc1ccc(C(=O)NCc2noc(-c3cccs3)n2)c(OC)c1 +NC(C(=O)NCC1CCCO1)c1ccc(Cl)cc1 +CCOCCCC(=O)Nc1c2c(nn1C)CCC2 +O=C(NC1CC1)c1ccc(Cl)cc1-n1cnnn1 +CCC(C)C(=O)N1CC(=O)N(c2ccc(OC)cc2)C(C)(C)C1 +CCOCc1cccc(CNC(=O)c2nccn3ccnc23)c1 +Cc1cnc(NC(=O)CC2CCCN(C(=O)NCC(C)C)C2)s1 +CCCN(CC1CCCCO1)C(=O)Cc1ccc(F)c(F)c1 +Cc1ccccc1C(CC(=O)Oc1ccc(F)cc1)NC(N)=O +CC(=O)NCC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +CC(=O)Nc1cc(NC(=O)N(C)Cc2cc(C)on2)ccc1F +O=C(NC(CO)Cc1ccccc1)c1c(F)cccc1F +COc1ccccc1NC(=O)CNC(=O)c1ccc(F)cc1 +COCCn1c(C(=O)NCC(C)C)nc2ccccc2c1=O +CC1CC1C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +COc1ccc(-c2nnc(SCCC(N)=O)n2C(C)C)cc1 +CC(C)Nc1cccc(CNC(=O)c2cnn(-c3ccccc3)n2)c1 +Cc1ccc(S(=O)(=O)C2OC(CO)C(O)C(O)C2O)cc1 +COc1ccc(-n2ccc3c(nnc4nc(C)nn43)c2=O)c(OC)c1 +CC(=O)N1CCCC1C1NCCc2c(F)cc(F)cc21 +Cc1ccc(C)c(C(=O)NCC(=O)Nc2nccs2)c1 +Cc1csc(C(C#N)C(=O)CCC(=O)c2cccs2)n1 +CCC(CC)NC(=O)C(C)NC(=O)c1ccc(Br)cc1 +Cc1noc2ncc(C(=O)N3CCN(C(=O)CO)CC3)cc12 +Cc1nc(N)nc(COc2ccc(-c3ccccc3)cc2)c1C(N)=O +CCN(CC(F)(F)F)S(=O)(=O)c1ccc(C)cc1C +CN(C(=O)c1ccc(C(N)=O)cc1)C1CCCCC1 +O=C(c1ccc(-n2cccc2)cc1)N1CCCN(c2cccnn2)CC1 +O=C(CSc1ncnc2nc[nH]c12)c1cccc(Cl)c1 +CC(=O)c1cc2c(cc1NC(=O)C1CC1)OCCO2 +Cc1noc2nc(C(C)C)cc(C(=O)NC3Cc4ccccc4C3)c12 +Cn1cc(NC(=O)COCCOc2ccccc2)cn1 +Cc1nc(N(C)C)ncc1C(=O)N(C)C(C)c1cc2ccccc2[nH]1 +CN(C)c1ccccc1NC(=O)NCc1ccoc1 +c1ccc(-c2nc[nH]c2-c2cccn2-c2cccnc2)cc1 +Cc1ncsc1CCOC(=O)c1cnc2ccccn2c1=O +NC(=O)C(OC(=O)Cc1cccc2ccccc12)c1ccccc1 +COC(=O)c1cccc(C(=O)N2CCN(CCO)CC2)c1 +COc1ncccc1CNC(=O)N(C1CC1)C(C)C(C)C +COc1ccc(CCNC(=O)Cn2cccn2)cc1 +Cc1ccc(-c2c(C#N)nnn2-c2nnc(C(C)C)s2)cc1 +O=c1[nH]cnc2c1sc1nc(-c3cccs3)ccc12 +CC(=O)c1csc(NC(=O)COc2ncnc3ccccc23)n1 +Cc1ccccc1N1CCN(CC(=O)NCc2ccccc2)CC1 +CCc1ccc(NC(=O)c2ccc(NS(C)(=O)=O)c(C)c2)cc1 +NC(c1ccccn1)c1nc2ccccc2n1Cc1ccccc1 +c1ccc(C(CNc2ncnc3[nH]ncc23)N2CCOCC2)cc1 +CC(C)(CNC(=O)NC1CCSc2ccccc21)c1ccncc1 +CCCC(C)(CO)NC(=O)NC1CCN(c2cc(CC)ncn2)CC1 +C=C(c1ccccc1)C1NCCc2cc(OCC)c(O)cc21 +Cc1ccc(Cl)cc1NC(=O)C1CCN(C(=O)N(C)C)CC1 +O=C(N1CCN(c2ccc(O)cc2)CC1)C1(c2ccccc2)CC1 +CCN(CCO)C(=O)c1sccc1Br +Cc1nn(-c2ccccc2)c(C)c1CC(=O)C(C#N)c1ccccn1 +CC(=O)Nc1cccc(NC(=O)CC(C#N)c2cccs2)c1 +Cc1cc(NC(=O)CCc2ccsc2)ccc1N1CCCC1=O +CC(C(=O)N1CCN(Cc2ccc3c(c2)CCO3)CC1)n1cncn1 +CC(Oc1ccccc1C#N)C(=O)Nc1cc[nH]n1 +CCCC(=O)N1CCC(C(=O)Nc2ccc(NC(=O)CC)cc2)CC1 +CCN(CC)C(=O)CCC(=O)N(C)c1cccc(C#N)c1 +COC(=O)C1(N(C)C(=O)CCN2CCCC2=O)CCCCC1 +CCNS(=O)(=O)c1ccc2c(c1)C(C)C(=O)N2 +CCOC(=O)C1=C(CNc2cccc(F)c2F)NC(=O)NC1C +CC(=O)c1ccc(NC(=O)NCCNC(=O)c2ccco2)cc1C +CCc1nnc2n1CCN(Cc1ncc(-c3ccc(Cl)cc3)o1)C2 +Cn1ccc(C(=O)Nc2nnc(-c3cc(Cl)ccc3Cl)o2)n1 +O=C(c1cccc(OCC(F)F)n1)N1CCN2C(=O)NCC2C1 +CC1CN(Cc2ccc(CNC(=O)Cc3ccon3)cc2)CC(C)O1 +Cn1cc(C#N)cc1C(=O)NC1CCN(c2c(F)cccc2F)C1=O +Cc1ccc(NC(=O)c2sc(N)nc2-c2ccccc2)c(O)c1 +COc1cccc(-c2nccn2Cc2cccc(C#N)c2)c1 +CC(C)NC(=O)NCc1cccc(CN2CCCC2=O)c1 +Cc1nc(NC(=O)c2cc[nH]n2)sc1-c1ccccn1 +COc1cc(S(=O)(=O)NCc2cccs2)ccc1F +Cc1cccc(CC(=O)NCCC(O)c2ccco2)c1 +CCCC1CN(C(=O)Cc2cc(C)[nH]n2)CCO1 +Cc1csc(-c2cn(C)c(=O)n(Cc3c(C)noc3C)c2=O)n1 +COc1cc(CNC(=O)N(C)CC(C)C)ccn1 +C=CCOCc1nnc2n1CCN(Cc1cnn(C)c1)CC2 +CC1CN(C(=O)NCc2ccccc2-n2ccnc2)CCO1 +COCCN(CC(F)F)C(=O)c1cn(C)nc1-c1cccs1 +CC(C)C(=O)N1CCN(C(=O)CSc2nc3ccccc3o2)CC1 +Cc1ccccc1SCC(=O)N1CCN(C(=O)C2CCCO2)CC1 +COCCCNC(=O)c1cncn1-c1ccccc1 +Cc1oc(C)c(C(=O)Nc2ccc(C(=O)OC(C)C)cc2)c1C +CC1CCN(S(=O)(=O)c2ccc(N)cn2)CC1 +C#Cc1cccc(NC(=O)c2ccccc2SC(C)C(=O)OC)c1 +N#Cc1cc2cc3c(cc2nc1N1CCOCC1)NCCC3 +COCCn1nc(C(=O)N2CCOC3CCCCC32)ccc1=O +O=C(c1cnccn1)N1CC2CCC(C1)N(C(=O)c1ccoc1)C2 +COc1ccc(OCCCC(=O)N2CCCC2)cc1 +CCC(CC)N(C)C(=O)Nc1cccc(S(=O)(=O)N(C)C)c1 +CCC(CCO)NC(=O)NC1CCCC(C(=O)NC(C)C)C1 +Cn1nc(C(=O)N2CCCCC2CCc2ccccc2)ccc1=O +COc1ccc(C(C)NC(=O)N(C)CCN2CCOCC2)cc1F +Cc1ccccc1C(=O)Nc1ccc(NC(=O)C2CC2)cc1O +CC1CN(CCOc2ccccc2Br)C(C)CO1 +CC(=O)c1ccccc1NC(=O)Cn1c(-c2cnccn2)noc1=O +COc1cc(C(=O)OC(C)c2nnc(C)o2)ccc1Cl +Cc1nc(C2COCCN2Cc2c(C)noc2C)cs1 +CC1CCC(N(C)C(=O)CN2CCCc3c(C(N)=O)cccc32)CC1 +CC(NC(N)=O)C(=O)N(C)C(C)c1ccccc1F +CCCCCn1c(=O)[nH]c2cc(C(=O)NC3CCCC3)ccc2c1=O +O=C(c1ccn2nnnc2c1)N1CCCC(c2nc3ccccc3[nH]2)C1 +Cc1ccc(C(=O)N2CCCC(C(=O)N(C)C3(C#N)CCC3)C2)cc1 +COC(=O)Nc1cc(NCc2noc(-c3cccs3)n2)ccc1F +Cc1csc(C(=O)N2CC(c3nc(-c4ncccn4)no3)C2)c1 +Cc1ccccc1NC(=O)N(Cc1ccco1)C1CCOCC1 +Cc1cc(C(=O)OC(C)C(=O)Nc2ccc(F)cc2Cl)c(C)o1 +CC(=O)N1CCC(NC(=O)C2CCCCN2S(C)(=O)=O)CC1 +O=C(c1ccncc1)N1CCSc2ccc(C(F)(F)F)cc21 +Cc1csc(C(C)N(C)C(=O)Cn2ncc(N(C)C)cc2=O)n1 +CC(O)c1nc2cccnc2n1Cc1cccc(C#N)c1 +Nc1nonc1NC1CC(=O)CC(c2ccccc2)C1 +CC1CCC(CNC(=O)Nc2ccnn2C(C)C)CC1 +CCCC(=O)NCC(=O)Nc1cccn(Cc2ccccc2)c1=O +O=C1OCCC1Sc1nc(-c2ccc(Cl)cc2)cs1 +CCOCC(=O)N(C)Cc1csc(C#CCCO)c1 +CCn1c(=O)c(=O)n(CC(=O)N2CCOCC2)c2ccccc21 +NC(=O)c1ccc(NC(=O)CC2OC(=O)c3ccccc32)cc1Cl +NC(=O)Cn1ccc(=O)c2cccc(C(F)(F)F)c21 +COc1ccc(S(=O)(=O)NCCC(=O)N(C)c2ccccc2)cc1 +c1cnc(N2CCOC3C(OCc4cccnc4)CCC32)nc1 +CCOC(=O)Cn1c(-c2ccccc2OC)ccc(C#N)c1=O +Cc1ccccc1-n1ccnc1S(=O)(=O)Cc1c(C)noc1C +Cc1ccc(NC(=O)c2cn3nc(C)c(=O)nc3s2)cc1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(S(=O)(=O)NC)cc1 +COc1ccsc1C(=O)NC(C)CC(=O)c1cccs1 +CS(=O)(=O)c1cccc(OCCSc2nc3ccccc3o2)c1 +CN1CCN(C(=O)Cc2cn(C)c3ccccc23)CC1 +O=C1OC(C(=O)NCc2ccncc2)Cc2ccccc21 +CC(=O)c1ccccc1NC(=O)c1c[nH]c2cc(F)cc(F)c2c1=O +CN(C)S(=O)(=O)c1ccc(C(=O)NCc2ccccn2)cc1 +Cc1nn(C)c(C)c1NC(=O)c1cccc2c1OC(C)C2C +NC(=O)CCN(Cc1ccccc1)C(=O)Cc1noc2ccccc12 +CC(C)(O)CN1CCN(C(=O)c2ccc3c(c2)COC3)CC1 +CNS(=O)(=O)c1csc(C(=O)N2CCc3ccc(F)cc32)c1 +CC(C)(C)C(O)CCNC(=O)Nc1ccccc1C(F)(F)F +Cc1ccccc1OCC(=O)Nc1ccc(N)cc1Cl +OCC#Cc1ccccc1OCCc1cccnc1 +CS(=O)(=O)N(C(=O)C1CCCC1)c1cccc(O)c1 +CCCCC(=O)NCc1nnc(C(=O)Nc2ccc(F)cc2)s1 +Cc1occc1C(=O)NC(Cc1ccccc1)C(=O)NC1CC1 +COc1cc(NC(=O)c2ccccc2)c(C(=O)NC2CC2)cc1OC +CN(CC(=O)Nc1ccccc1F)c1ccccc1 +CCCn1nccc1C(=O)N1CCC(Cc2cccc(C(N)=O)c2)C1 +COC(=O)COc1cc(C)cc2oc(=O)c(C)c(C)c12 +COc1ccc(OC)c(C(C#N)NC(=O)c2cccc(F)c2)c1 +Cc1ncc(C(C)NCc2cccc(C(N)=O)c2)s1 +FC(F)Cn1cc(NCc2cnc3ccsc3c2)cn1 +Cc1ccc(-c2nc3nc(N)n(C)c(=O)c3[nH]c2=O)cc1 +COC(=O)Cc1csc(COc2ccccc2Cl)n1 +O=S(=O)(CC1CCOCC1)NCC1(c2ccc(F)cc2F)CC1 +COc1ccc(CN2CCc3ncnc(-c4cccnc4)c3CC2)cc1 +Nc1cc(NC(=O)CCCN2CCCC2=O)ccc1Cl +Cc1cc(C)n(CC2CCCCN2C(=O)CCCc2ccccn2)n1 +COC(Cc1ccc2c(c1)N(C)C(=O)C(C)O2)(OC)OC +Cc1ccc(COc2ccc(CC(=O)NCCO)cc2)cc1 +COc1ccc(CCNC(=O)c2cnc(SC)nc2C)c(OC)c1 +CNC(=O)NC(C)(C)C(=O)NCCc1ccccc1F +Cc1ccc(CC(=O)NCc2ncc(-c3ccccc3)o2)s1 +COc1cccc(CN2CCN(c3ccccc3OC)CC2)c1 +CCNC(=O)C1CCN(c2nc(C)c3cc(C)ccc3n2)CC1 +Nc1cccc(CCC(=O)NCc2ccccc2)c1 +C=CCn1c(=O)oc2ccc(C(=O)NCC3CCCO3)cc21 +C=CCN(Cc1ccco1)C(=O)c1cccc(Oc2ncccn2)c1 +CCC(NC(=O)Nc1ccc2c(c1)COC2)c1nc(C)cs1 +CC1CCCC(NC(=O)NC2CCN(C(=O)c3ccoc3)CC2)C1C +Cc1cccc(C)c1OCCCNC(=O)N1CCOCC1C +Cc1ccc(C(=O)CCC(=O)NC2(C)Cc3ccccc3C2)s1 +COCCOc1cccc(NC(=O)c2cccc(C)c2)c1 +CC1CC(C)CN(C(=O)C(C)Sc2n[nH]c(N)n2)C1 +O=c1ccccn1CCCCNc1ncccc1F +O=C(C1CCC1)N(CCc1cccc(F)c1)C1CC1 +CC(=O)c1ccc(S(C)(=O)=O)c(N(C)Cc2sccc2C)c1 +Cc1ccsc1CNC(=O)CN1C(=O)CCOc2ccccc21 +CCCCS(=O)(=O)N1CCC(c2cc(-c3ccccc3)[nH]n2)CC1 +N#CCCN1CCN(c2ccc(Oc3ccccc3)cc2)CC1 +CN1CC(NC(=O)N2CCc3ccc(Cl)cc3C2)CCC1=O +CCC(C)C(NC(N)=O)C(=O)NCc1cccc2ccccc12 +Cc1nc(SCC(=O)N2CCC(O)CC2)c(C#N)c(C)c1C +O=C(c1csc2c1CCCO2)N1CCCN(C(=O)C2CCC2)CC1 +CCOC(=O)c1nnn(-c2nonc2NC(C)=O)c1C +O=C(NCc1ccccn1)c1ccc2nc(Cc3ccccc3)oc2c1 +COc1ccccc1CC(=O)NCCOc1ccccc1 +CC(C)CCC1=NC(=O)C2(CCN(C(=O)C3CC34CCCC4)CC2)N1 +O=C(CC1Sc2ccccc2NC1=O)OCC1CCCCO1 +CC(C)CNC(=O)C(C)N1c2cccc3cccc(c23)S1(=O)=O +COc1ccc(C(=O)CN2CCc3ccccc32)cc1 +CC(=O)Nc1cccc(C(=O)Nc2cccc3c2CCCC3)c1 +Cn1cc(CNC(=O)CCCSc2ccc(Cl)cc2)cn1 +Cc1cc(C(=O)NCCc2nc(C)c3c(n2)CCC3)no1 +CN(Cc1ccccc1Cl)C(=O)CCn1ccccc1=O +CCn1ncc(Cl)c1-c1nc(C2CCOC2)no1 +Cc1cc(N2CCC(N3CCc4ccc(Cl)cc4C3)C2=O)n(C)n1 +CCN1CC(C(=O)NC(C)(C)CC2Cc3ccccc3C2)CC1=O +CCOC(=O)N1CCN(C(=O)Cc2cnc(-n3cccc3)s2)CC1 +Cc1ccn2c(CN3CCOC(c4ccccc4F)C3)cnc2c1 +CNC(=O)Nc1cccc(NC(=O)CNC(=O)OCC(F)(F)F)c1 +CN(Cc1ccc(F)cc1Cl)C(=O)C1CC2CCC1O2 +COc1ccc(-c2c[nH]c(=O)nc2N)cc1Cl +Cc1cnn(CCC(=O)NC(c2ccccc2)c2n[nH]c(C)n2)c1 +O=C(Nc1ccc(F)c(F)c1F)C1CN(S(=O)(=O)C2CC2)C1 +Cc1occc1-c1nnc(CCC(=O)NCC(=O)N(C)C)o1 +N#CC(CCN1CCOCC1)c1cccc2ccccc12 +COc1ccc(OC)c(C(C)Nc2ccc3nnnn3n2)c1 +O=C1NC(c2ccc(O)c(Cl)c2)N2CCCCC12 +COc1ccc(CCC(=O)Nc2ccc(C)cc2)cc1N +O=S(=O)(c1ccccc1)N(Cc1ccsc1)C1CC1 +CC(NC(=O)Cc1cccc(F)c1)c1ccc(-n2cncn2)cc1 +Cc1nc(C)c(CCNC(=O)NC(C)c2ccncc2)s1 +CC(C)(C)OC(=O)Nc1ccc(Cl)cc1N1CCOCC1 +CC(Oc1ccc(-c2nnco2)cc1)C(=O)Nc1cccc(F)c1 +CCCc1cc(CNC(=O)Cn2ccnc2-c2ccccc2)on1 +CC(C)N(CCCO)C(=O)Cc1ccccc1F +O=C(Nc1nccs1)c1ccc(-c2ccco2)[nH]c1=O +Cc1cc(C)cc(NC(=O)COC(=O)c2ccc3c(c2)OCCO3)c1 +COCc1nc2c(NC(=O)COc3ccccc3C)cccn2n1 +Cc1cc(C)n(-c2ccc(NC(=O)N(C)Cc3ccccn3)cn2)n1 +O=C(Cc1noc(-c2ccc(F)cc2)n1)Nc1ccc(F)cc1 +CCC(NC(=O)c1ccccn1)c1cccc(Cl)c1 +Cc1ccc(N2CCCC(NC(=O)NCc3ncn(C)n3)C2=O)cc1 +COc1ccc(C(=O)c2nn3c(nc(=O)c4ccccc43)s2)cc1 +Cc1ccc(-c2nc3ccccc3[nH]2)cc1NC(=O)C1CCCO1 +C=CCn1ncnc1C(O)(c1ccccc1)c1ccccc1 +O=c1c2ccccc2ncn1CCCCn1cnc2ccccc2c1=O +CN(CCOc1cccc(Cl)c1)C(=O)c1cccnc1 +Cc1cccc(CN2CCCCC2C(=O)OCC(N)=O)c1 +CN(C)C(=O)c1cccc(-c2cccc(-c3cc[nH]n3)c2)c1 +Cn1c(C(=O)Nc2ccc(C(N)=O)cc2)cc2cc(F)ccc21 +CCCN(C)C(=O)Nc1ccc(F)cc1OCC +CCCc1nc(CNc2cccc(C)c2C(N)=O)cs1 +COC(=O)c1n[nH]c2ccc(NC(=O)c3cc(C)on3)cc12 +CC(NC(=O)c1cccc(Cn2cccn2)c1)c1n[nH]c(=O)[nH]1 +CCOCCC(=O)Nc1ncn(CC(=O)N2CCCCCC2)n1 +CCCC1CN(C(=O)C(Oc2ccccc2C#N)C(C)C)CCO1 +COc1ccc(CC(C)C(=O)Nc2ccc(C#N)cn2)cc1 +COc1ccc(F)c(-c2cc(N)n[nH]2)c1Br +Cc1ccc(C(O)CNCc2ccccc2Cl)cc1 +O=c1[nH]c2ccccc2n1CCCc1ccccc1 +C=CCOc1ccc(CN(C)c2cc(=O)n3ccccc3n2)cc1 +COc1cccc(NC(=O)C(C)c2ccsc2)c1 +Cc1ccncc1NC(=O)N(C)Cc1ccc(S(C)=O)cc1 +O=C(Nc1ccncc1)c1ccccc1Br +COCCCC(=O)NCc1cccc2ccccc12 +Cc1ccc(F)cc1NC(=O)NCc1ccccc1 +Cc1cnn(C)c1C(=O)Nc1nnc(-c2ccc(Cl)cc2)o1 +C=CCNC(=O)c1ccccc1NC(=O)c1cc(C)sc1C +CN(C)C(=O)COc1ccc(NC(=O)CC2C=CCC2)cc1 +CC(Sc1ccccn1)C(=O)NCCC(=O)Nc1ccccc1 +Cc1cc(C(=O)NCc2cccs2)nc(N(C)C)n1 +Cc1csc(N2CCN(CC3(O)CCCCC3)CC2)n1 +COCCN1CCN(C(=O)C2(C#N)CCCCC2)CC1=O +COC(=O)C(NC(=O)c1cccc(NC(=O)C2CCCC2)c1)C1CC1 +Cc1cc(C(=O)N2CCc3sccc3C2C)c2c(C)nn(C)c2n1 +Cc1cc(C(C)NC(=O)Nc2ccc3c(c2)oc(=O)n3C)c(C)s1 +CC(Oc1ccc(C#N)cc1)C(=O)NC1CCCC1 +CCCCNC(=O)C(N)c1cc(OC)cc(OC)c1 +OCc1ccc2nc(CCc3ccccc3)oc2c1 +CNC(=O)C1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 +CCCCN(CC)C(=O)c1cnn2c1OCCC2 +CN(C)C(=O)C1CC2C(CCN2Cc2nccs2)O1 +Cc1cc2c(cc1NC(=O)N1CCCCC1CO)OCO2 +Cc1cccc(C)c1OCC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +Cc1nc(-c2ccccc2)sc1C(=O)NCC(=O)N1CCCCC1 +COC(=O)c1cccc(NCC(=O)NCc2ccccc2)c1 +CC(C)c1nnsc1CNC(=O)c1ccc2[nH]c(CO)nc2c1 +COC(=O)c1ccc(F)c(NC(=O)NCc2ccoc2)c1 +CCOC(=O)c1sc2nc(C)nc(N(CC)CCO)c2c1C +Cc1ccc(S(=O)(=O)Cc2ccc(C(=O)N(C)C)cc2)cc1C +CCCC(=O)N1CCC(C(=O)Nc2ccn(C)n2)CC1 +CCOc1cc(F)ccc1NC(=O)N(C)Cc1cccc(C#N)c1 +Cc1nnc(SCc2ccc(C#CCO)s2)o1 +CC(CC(C)(C)c1ccccc1)NC(=O)c1c[nH]c2ccccc2c1=O +CCC(=O)N1CCC(NC(=O)Nc2ccc(C(C)=O)c(C)c2)C1 +Cc1ccc(C(=O)CCC(=O)NCC(C)(C)c2ccncc2)s1 +CCSc1ccc(C(C)NC(=O)c2ccc(OC)nn2)cc1 +Nc1ncnc(N2CCC(Cc3ccccc3)CC2)c1N +N#Cc1nnn(Cc2cccc(F)c2)c1COc1ccccc1 +COc1ccccc1-c1nn2c(-c3ccco3)nnc2s1 +O=C(c1cc[nH]n1)N1CCc2ncnc(NCc3ccccn3)c2CC1 +N#Cc1c(N)c(C(=O)c2ccc(Br)cc2)n2c1CCC2 +O=C(COc1ccccc1)Nc1cnn(-c2ccccc2F)c1 +CCC(=O)N1CCc2ccc(NC(=O)c3cc(C)oc3C)cc2C1 +O=C(CNC(=O)c1ccc2c(c1)OCO2)Nc1nnc(C2CC2)s1 +O=C(Nc1cc(-n2cccn2)ncn1)C1CC=CCC1 +CS(=O)c1ccc(C(=O)Nc2ccccn2)cc1 +COCCC(C)C(=O)Nc1cc(C(C)C)c(O)cc1C +COc1ccc(S(=O)(=O)c2oc(C(C)(C)C)nc2C#N)cc1 +CCc1ccccc1CNC(=O)NCC(C)(C)N1CCOCC1 +Cc1cccc(NC(=O)CCSc2ccccn2)n1 +CCn1c(C)cc(C(=O)Nc2cc(F)ccc2C)c1C +Cc1ccc(C(=O)NCCc2nnc3ccccn23)o1 +CC(C)c1ncc(OCC2CCOC2)c(CO)n1 +O=C(c1cc(F)cc(Cl)c1O)N1CCOCC1C1CC1 +Cc1cnc(-c2nc(Cc3cccc(Cl)c3)no2)cn1 +CCOc1ccc(-c2nc3cc4c(cc3[nH]2)OCO4)cc1N +CC1CCC(NC(=O)NCC2CC(=O)N(C3CC3)C2)c2ccccc21 +CCOC(=O)N1CCC(CCC(=O)Nc2cccc(OC)c2)CC1 +CN(C)C(=O)Cn1cc(NS(=O)(=O)c2ccccc2)cn1 +Cc1cccc(N2CCN(C(=O)NCc3ncn(C)n3)CC2)c1C +C#CCN1CCN(C(C)C(=O)Nc2cc(C)no2)CC1 +Cn1c(=O)n(C)c2cc(C(O)C(=O)NC3CC3)ccc21 +O=C(C(c1cccc(F)c1)N1CCOCC1)N1CCc2cnccc21 +Cc1nc(C)n(C2CCCN(C(=O)C3CC(=O)N(CC4CC4)C3)C2)n1 +O=C(Cc1noc(Cc2c(F)cccc2Cl)n1)NC1CCCC1 +Cc1c[nH]c(=O)n1-c1ccc(C(=O)OCc2nc3ccccc3o2)cc1 +Cc1cc(C(=O)N(C)CC(C)C)c2c(C)noc2n1 +Cc1cc(OC(=O)CCCNC(=O)c2ccsc2)ccc1Cl +CCC1CCCCN1C(=O)CCc1cc(OC)c(OC)c(OC)c1 +O=C1NCCCCC1n1nnc2ccccc2c1=O +CC(NC(=O)c1csc(-c2cnccn2)n1)c1ccccc1 +NC(=O)C1=C(Nc2cccc(F)c2)c2ccccc2S1(=O)=O +O=C(Cc1nnc(-c2ccccc2)o1)NCC1CC1 +Cc1nc(C(CO)c2ccccc2)sc1CCO +O=C(CCC1CCCC1)Nc1nc(-c2ccccc2)n[nH]1 +COC(=O)c1cnn(-c2cc(Oc3ccccc3)nc(C)n2)c1N +CC(C)S(=O)(=O)c1ccccc1C(=O)N(C)Cc1cnn(C)c1 +COc1cc2c(cc1C)CCNC2c1ccccn1 +CCOc1ccc(-c2cc3n(c2)CCn2cccc2-3)cc1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)N(C)C +COCCNC(=O)NCC(O)c1cn(C)c2ccccc12 +CC(C)Cc1n[nH]c(-c2cccc(C#CC(C)(C)O)c2)n1 +C=CCc1cccc2cc(C(=O)N3CCCCC3)c(=O)oc12 +Cc1nn(C)c(C)c1C(=O)Oc1ccc2c(c1)CCC(=O)N2 +Cc1sc(-n2cnnn2)c(C(=O)Nc2ccc(C(N)=O)cc2)c1C +CCC(C)NC(=O)c1cccc(C(=O)NC(C)CC)n1 +CCOc1cc(NC(C)=O)c(OCC)cc1NC(C)=O +C=CCSc1nnc(NC(=O)Nc2ccc(F)cc2)s1 +CCc1c(C#N)cnn1-c1cc(Cl)ccc1OC +CCN(CC)C(=O)CNc1cccc(OC(C)C)c1 +CC1CN(Cc2ccc(-n3cncn3)cc2)C(c2ccccc2)CO1 +COc1ccc(OCCN(C)C(=O)c2c[nH]c3cccc(F)c23)cc1 +CNc1ccc(C2CN(Cc3cnn(C)c3)CCO2)nc1 +O=C(NCc1ccccc1)c1n[nH]c2c1CCCC2 +CCc1ccc(C2COCCN2Cc2ccc(OC)c(O)c2)o1 +Cn1ccnc1SCC(=O)NCc1coc(-c2ccccc2)n1 +O=C1OC(C(=O)NCc2cccc(-n3cccn3)c2)Cc2ccccc21 +CCC(C)(C)NC(=O)CCNS(=O)(=O)c1ccccc1 +Cc1ccnc(NCc2cn3nc(C)sc3n2)n1 +CC(OCC1CC1)C(=O)Nc1cccc(C(=O)Nc2ccncc2)c1 +CCCNC(=O)Cc1c(C)nc2nc(-c3ccccc3)nn2c1C +CC1CC(N2CCOCC2)c2cc(Cl)ccc2N1 +CN1CCC(C(=O)Nc2ncccc2OCC2CCCCC2)CC1=O +COCCn1cc(NC(=O)NC(c2ccccc2)C(C)(C)C)cn1 +COC(=O)c1ccc(CSc2ncccn2)o1 +CCc1cc2c(=O)n(CC(=O)C(C)CC)cnc2s1 +CN(Cc1nccn1C(F)F)C(=O)C1CCC(=O)N1 +Cc1ccccc1-c1noc(=O)n1CC(=O)N1CCCC1 +CC(=O)c1ccc(C)cc1OCC(=O)NC(C)c1ccco1 +Cc1ccccc1Cc1nnc(NC(=O)CC2CCC(=O)N2)s1 +CCC(NC(=O)CSc1nncs1)c1ccc(C)cc1 +c1ccc(-c2ncc(CN3CC(c4cccnc4)C3)cn2)nc1 +COC(=O)Cn1c(C(C)O)nc2ccc(F)c(F)c21 +CC1CC1C(=O)NCCNC(=O)c1cccc(Br)c1 +Cc1ccc(NC(=O)Cc2csc(-c3ccoc3)n2)nc1 +CC(C)CNC(=O)C1CCCN(C(=O)c2ccn3ccsc23)C1 +CCc1nn2c(-c3ccncc3)ccnc2c1-c1ccccc1 +Cc1ccc(S(=O)(=O)N2CCCC2C(=O)OCC(C)C)s1 +Cc1ncsc1CNC(=O)c1cc(S(N)(=O)=O)oc1C +O=C(NCc1ccc(Br)cc1Cl)Nc1nncs1 +COC(=O)C1CCCN1Cc1ccc(-n2cccn2)cc1 +CCc1nc(-c2ccc(C(=O)Nc3ccc4c(c3)COC4)cc2)n[nH]1 +O=c1[nH]c2ncccc2cc1-c1ccccc1Br +O=C(Nc1cc(Br)ccc1-n1cncn1)C1CCC1 +Cc1ccc(-n2cnnn2)cc1NC(=O)CCc1ccsc1 +CC1CCN(C(=O)c2ccccc2S(C)(=O)=O)C(C)C1 +CC(C)CCC(=O)N1CCCC(CNS(C)(=O)=O)C1 +C=C(C)COc1cccc(NC(=O)CNC(=O)NC)c1 +O=C(NCc1ccccc1CN1CCCC1=O)C1CC2C=CC1C2 +COc1cc(CNC(=O)c2ccc3c(c2)OCO3)ccn1 +O=C(c1ccncc1F)N(CCN1CCOCC1)Cc1ccco1 +O=C(NC1CCCC(C(F)(F)F)C1)c1cn2cccnc2n1 +COCCOc1ccccc1NC(=O)c1csnn1 +CCN(CC)S(=O)(=O)N1CCN(C(=O)c2cc(Cl)c[nH]2)CC1 +CCC1(C(N)=O)CCN(C(=O)OC(C)(C)C)CC1 +Cc1nc(C)n(CC2CCCCN2c2ccc(C#N)cn2)n1 +Nc1cc(F)ccc1C(=O)OCC(=O)N1CCOCC1 +Cn1ncc2c(C(=O)Nc3ccccc3)cc(C3CC3)nc21 +COc1c(C)cnc(CNC(=O)NCCC(=O)N(C)C)c1C +CCCNC(=O)C1CCCN(Cc2nc3c(cnn3C)c(=O)[nH]2)C1 +C#CCNC(=O)COC(=O)c1csc(-c2ccc(CC)cc2)n1 +Cc1cccc(N2CCN(C(=O)c3cc(C(N)=O)cs3)CC2)c1C +CC(C)Oc1ccc(C(=O)OCC(=O)Nc2ccc(C#N)cc2)cc1 +CC1CCCC(NS(=O)(=O)c2ccccc2C#N)C1 +N#CC1(NC(=O)CSc2nncn2-c2ccccc2)CCCC1 +CC(C)(C)NC(=O)CNC(=O)c1cccc(NC(=O)c2ccco2)c1 +COc1ccc2c(ccn2CCC(=O)NCc2nc3ccccc3[nH]2)c1 +O=C(NCc1ccc(F)cc1F)c1n[nH]c2c1CCCC2 +COc1ccc(OC)c(CC(=O)Nc2cc(C)n[nH]2)c1 +O=C(NCC1CCCO1)c1ccc(F)c(S(=O)(=O)NC2CC2)c1 +O=C(NCc1cc(=O)[nH]c2ccccc12)c1cccnc1-n1cccn1 +Cc1ccnc(NC(=O)COc2ccc(C)c(C)c2)c1 +CCN1CCN(C(=O)c2cn(C)nc2-c2ccc(F)cc2F)CC1 +CC(C)N1CC(C(=O)OC2CCCc3ccccc32)CC1=O +NC(=O)CCN(C(=O)c1ccc2c(c1)OCCO2)c1ccccc1 +COCc1ccc(C2CCCN2C(=O)Nc2ccc3c(c2)COC3)o1 +Cc1ccc(C(=O)NC2CCS(=O)(=O)c3ccccc32)c(O)c1 +Cc1cc(NC(=O)Nc2cnn(CCN3CCOCC3)c2)ccc1F +CC(=O)NCc1ccc(C(=O)N(C)CCOc2ccc(F)cc2)cc1 +COC(=O)C(C)NC(=O)c1cc(Cl)cn1C1CC1 +Cc1ccccc1CN(C)C(=O)COc1nnc2ccccn12 +COC(=O)C(C)NC(=O)c1cnc2scc(C)n2c1=O +CC(C)CN(CC(C)C)C(=O)CSc1nnc(N)n1C +Cc1noc(C2CC2)c1NC(=O)NCc1ccco1 +O=C(NCC(O)c1ccsc1)c1ccc(F)cc1 +N#Cc1cccc(OC2CCN(Cc3cccs3)CC2)c1 +CN(C(=O)c1ccc(N2CCOCC2)cc1)c1ccccc1 +CN(C)S(=O)(=O)c1ccc(Cl)c(C(=O)NCCO)c1 +Cn1c(=O)n2n(c1=O)C1C=CC2C2C3C=CC(C=C3)C21 +CCOC(=O)c1cc(NS(=O)(=O)c2ccccc2)c[nH]1 +O=C(NCc1ccnc(OCc2ccccc2)c1)C1CC1 +COc1ccc(CNc2ccc(C#N)cn2)cc1OC +CCc1onc(C)c1NC(=O)c1ccc(CNC(=O)OC(C)(C)C)o1 +CNC(=O)c1cccc(OC(=O)c2cnn(C(C)(C)C)c2)c1 +CC(C)N(C)C(=O)NCCCOCC1CCCO1 +CN(Cc1ccnn1C)S(=O)(=O)c1cc(Cl)ccc1Cl +CCCCCNC(=O)c1snc(-c2cccnc2)c1N +NC(=O)Cn1cc(NC(=O)N2CCOC(c3ccc(F)cc3)C2)cn1 +CC(C)NS(=O)(=O)c1ccc(F)c(C(=O)NC2CC2)c1 +CCc1c(C)sc2ncn3nc(Cn4nccc4C)nc3c12 +O=C(Nc1c(O)c(Cl)cc(Cl)c1Cl)c1cnccn1 +CCCOc1cc2c(cc1OC)CCNC2CO +CCOc1ccc(NC(=O)c2ccc(CC)s2)cc1CO +COCCn1c(C)cc(C(=O)CN2CCc3ccccc32)c1C +COc1cccc(NC(=O)Nc2nnc(-c3ccncc3)s2)c1 +Fc1cc(Cl)cc2c1C(c1nccs1)NCC2 +Cc1nc(-c2cccc(CNC(=O)COC3CCCC(C)C3)c2)n[nH]1 +Cc1nc(C)c2c(C)c(C(=O)OC(C)C)sc2n1 +Cc1nc(NCCC2CCOC2)c2c(C)nn(C)c2n1 +O=C1COc2ccc(C(=O)NC3CCCCCC3)cc2N1 +Cc1nc(C#N)c(Cc2ccccc2)c(C(F)(F)F)n1 +CCCCNC(=O)CCN1C(=O)COc2ccc(C)cc21 +COCc1ccc(C(=O)N2CCC(c3c[nH]c4ncccc34)CC2)o1 +CCOc1ccc2ccn(CC(C)C#N)c(=O)c2c1 +Nc1nc(N2CCCCCC2)ncc1C(=O)NCc1ccccc1 +CN(C(=O)COc1ccccc1C#N)C1(C#N)CCCCC1 +COc1cccc(CNCCc2cccc(F)c2)c1 +Nc1cc(C(F)(F)F)ccc1NCc1ccc2c(c1)OCO2 +Cc1ccnc(NCCCN2CCc3ccccc32)n1 +CC(=O)c1cccc(OCC(=O)N(C)Cc2ccsc2)c1 +CC(O)CC(C)CNC(=O)Nc1ccc(S(C)(=O)=O)cc1 +O=C(C1CCOCC1)N1CCN(Cc2c(F)cccc2Cl)CC1 +COc1ccc(F)cc1NC(=O)c1csc(-c2ncccn2)n1 +COCCCC(=O)NC(c1ccccc1)c1cccc(F)c1 +CC(C)c1ccc(-n2nnc(CO)c2C2CCCO2)cc1 +Cc1ccc2nc(NC(=O)CN3CCC4(CC3)OCCO4)sc2c1 +CCOC(=O)c1cnn(C2CCCN(C(=O)c3cscn3)C2)c1 +CCN(C(=O)COc1ccc2ccc(OC)cc2c1)C1CC1 +CNc1cc(C(=O)N2CCCCC2CCc2ccc(O)cc2)ccn1 +Cc1ccc(OCCC(=O)NC2c3ccccc3CC2O)cc1C +COc1ccc(-c2nc(-c3ccc(C)nn3)no2)c(O)c1 +COCCNC(=O)CN(C)c1ncnc2sc(C)c(C)c12 +Nc1c(NCc2ccccc2)ncnc1N1CCOCC1 +COc1cc(C)c(NC(=O)CCn2nc(C)cc2C)cc1OC +O=C(Cn1nc(-c2ccc(F)cc2)oc1=O)c1cc(F)ccc1F +Cc1nc(Nc2ccc(F)cn2)sc1C(=O)NCc1ccccn1 +Cc1cccc(CN2CCN(C(=O)c3cccc(C)c3O)CC2)c1 +CC(C)N(CC(=O)Nc1nncs1)c1ccccc1 +CCOc1cc(C#N)ccc1OCC(=O)N1CC(C)OC(C)C1 +CC1CCC(NC(=O)c2ccc(=O)n(Cc3ccccc3)n2)CC1 +CN(CC(C)(C)CN1CCOCC1)C(=O)NCc1ncn(C)n1 +CC(C)C(NC(=O)C1CCCC1)c1ccc2[nH]c(=O)oc2c1 +Cc1cccc(=NS(=O)(=O)c2ccccc2F)[nH]1 +COc1ccc(C2CCCCCN2C(=O)C2CCN(C)C(=O)C2)cc1 +Cc1nn(-c2ccc(Br)cc2)c(C)c1N +CCOC(=O)CN1CCCC1c1nc2ccccc2s1 +CCC(C)(C)NC(=O)c1[nH]c(C)c(C(=O)OC(C)C)c1C +COc1cc2nc(-c3ccccn3)[nH]c(=O)c2cc1OC +C#CCOc1cccc(COC(=O)c2ccnc(C3CC3)n2)c1 +Cc1cc(CN2CCN(C(=O)CCc3ccncc3)CC2)no1 +CNC(=O)NCC(=O)NC(c1ccc(CC(C)C)cc1)C(C)C +Cn1cc(C2Sc3ccccc3NC2=O)c2ccccc21 +O=C(NCCCN1CCOCC1)c1sccc1Br +CCNC(=O)CN(C)C(=O)c1cc(Cl)cc(Cl)c1 +O=C(Nc1cn[nH]c1)c1cccc(C(F)(F)F)c1F +CCC(C)NC(=O)c1ccc2c(c1)CCCN2S(C)(=O)=O +CC(C)COc1ccc(C(=O)Nn2cnnc2)cc1 +O=C(Nc1cccnc1)C1CC(=O)N(Cc2ccco2)C1 +O=S(=O)(Nc1ccc2c(c1)OCCO2)c1ccc2c(c1)CCN2 +CS(=O)(=O)NCCNc1ccc(N)c(C(F)(F)F)c1 +O=C1CCC(C(=O)NC2CCN(c3ccccc3)CC2)O1 +Cc1ccc(-c2csc(NC(=O)c3ccc(=O)n(C)n3)n2)o1 +Nc1cc(C(O)CNc2ccc(Cl)cc2)ccc1F +COc1cccc(NCCNc2c(C)cccc2C)c1 +CCN1CCN(C(=O)CC(C#N)C2CCCCC2)CC1 +Cc1ccc(C)c(C(=O)N2CCN(c3nccs3)CC2)c1 +CCC(=O)Nc1ccc(C)c(NC(=O)NCc2ccccc2F)c1 +Cc1ncnc(-c2ccc3c(c2)NC(=O)CS3)c1N +CCc1cc(=O)n2nc(N3CCCC(c4ccn[nH]4)C3)sc2n1 +COc1ccccc1CC(=O)NC(C)CCC(C)C +COc1ccc(CNc2nc(C)nc3sc(C)c(C)c23)cc1 +CCN(Cc1c[nH]nc1-c1c(F)cccc1F)CC(C)C#N +CCn1c(COc2ccc(F)cc2Cl)nnc1SCC(N)=O +C=CCN(Cc1cccc(OCC)c1)C(=O)C1CCOCC1 +O=C(c1ccccn1)N1CCC(O)(Cn2ccc3ncccc32)CC1 +CN1CCC(NC(=O)Nc2cccc3cccnc23)C1=O +O=c1cc(-c2ccccc2)[nH]c2cc(C(F)(F)F)ccc12 +COC1CCCC1OC(=O)c1cccc(NC(C)=O)c1 +COCc1ccccc1CNC(=O)Nc1ccc2nc(C)oc2c1 +CCc1ccc(CC)c(NC(=O)c2cc(S(N)(=O)=O)c(C)o2)c1 +Cc1cccc(N(CCC(N)=O)C(=O)Cc2c(F)cccc2F)c1 +Cc1cc(N(C)Cc2cccs2)n2ncnc2n1 +COC(=O)C(CC(C)C)NC(=O)c1cnn(-c2ccccc2)n1 +COc1ccc(C(=O)NCC(O)c2ccc3c(c2)CCO3)cc1OC +CCn1nnnc1COc1ccc(C(=O)Nc2ccc(C)cn2)cc1 +CC1CCC(NC2C(=O)Nc3ccc(F)cc32)CC1 +COc1ccnc(NC(=O)CNC(=O)c2c(F)cccc2Cl)c1 +CNC(=O)c1ccc(NC(=O)COC(=O)c2cccc(C)c2O)cc1 +CC(c1ccc(Cl)cc1Cl)N(C)C(=O)c1cnccn1 +Cc1noc(C)c1CCC(=O)N(C)Cc1ccccc1F +COC(=O)N1CCC(NC(=O)c2cc3ccc(F)cc3nc2C)CC1 +CC1CCN(C(=O)c2ccc3c(c2)CC(=O)N3C)CC1 +O=C(Cc1c[nH]c2ccccc12)Nc1cnc(N2CCOCC2)nc1 +Cc1cc(S(=O)(=O)N2CCCC(C(N)=O)C2)ccc1F +CCOCCCNC(=O)Nc1ccc2nc(C)sc2c1 +N#Cc1cc(Br)ccc1NCCCN1CCCC1=O +CC1Oc2ccc(NS(=O)(=O)c3cccc(F)c3)cc2NC1=O +Cc1noc(C)c1CNc1ccccc1Oc1ncccc1C#N +Cc1cnc(CNC(=O)c2cnc(C(C)(C)C)[nH]c2=O)cn1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3ccc(C(N)=O)cc3)cc2)n1 +Cn1c(C2CC2)nc2cc(NC(=O)COCCc3ccccc3)ccc21 +CC(CNS(=O)(=O)N(C)C(C)C)N(C)c1ccccc1 +COCc1cc(-c2cccc(C(F)(F)F)c2F)ncn1 +CCC(C)C(NC(=O)c1cn(Cc2ccccc2)nn1)C(N)=O +Cc1cc2ncc(C(=O)NCCc3ccccc3)c(C)n2n1 +COc1cccc(NCc2ccc(OCC(N)=O)cc2)c1 +COc1ccc(C(C)=O)c(OC(=O)C2CC3CCC2O3)c1 +COc1ccc(NC(=O)N(C)Cc2cc(C(C)(C)C)n[nH]2)cc1C#N +CCCc1noc(Cn2nc3c4c(nc(CC)n3c2=O)CCC4)n1 +COc1ccc(NC(=O)Cn2nnnc2C(C)(C)C)cc1 +CCN(CCC#N)C(=O)COc1ccc(C(N)=O)cc1 +COCCNC(=O)Cn1nc(-c2cccs2)n(C2CC2)c1=O +CC(C)(C)c1nc(CNC(=O)Cc2c[nH]c3ccccc23)cs1 +COc1cccc(COC(=O)C2CCCN2C(=O)C2CCCC2)c1 +O=C1CN=C(c2ccc(F)cc2)c2cc(F)ccc2N1 +CCOc1ccc(C(=O)Nc2c(C)nc3ccc(C)cn3c2=O)cc1 +CCN(CC(C)C#N)C(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CCn1cc(C(=O)Oc2cccc(C(=O)NC3CC3)c2)cn1 +NC(=O)c1cccc(NC(=O)N2CCCC2C(=O)NC2CC2)c1 +O=C(NCc1nnc2ccccn12)N1CCc2ccc(Cl)cc2C1 +O=C(COc1cccc2[nH]ccc12)Nc1cccc2ncccc12 +Cc1cccc(OCC(=O)Nc2ccc(-c3cc[nH]n3)cc2)c1 +CN(C)C(=O)C12COCC1CN(S(C)(=O)=O)C2 +CCC(C)c1c(C)nn(C(=O)c2cc(OC)c(OC)c(OC)c2)c1C +Cn1nnc2c(=O)n(CC(=O)NCCc3ccccc3)cnc21 +NC(=O)C1CN(C(=O)c2cc3c(s2)CCCC3)c2ccccc2O1 +Cc1cc(=O)[nH]c(-c2ccc(NC(=O)CCC(C)(C)C)cc2)n1 +COc1cccc(NC(=O)CSc2nnc3[nH]c(=O)c(C)nn23)c1 +CCc1nc(CNc2ccccc2COC)cs1 +Cc1ccc(OCCC(=O)Nc2nncs2)c(C)c1 +COc1ccc(CNc2ccc(CC#N)cc2)cc1 +COc1cc(C(C)=O)ccc1OC(=O)C(C)Cc1ccccc1F +O=C(Nc1cccc(C#Cc2ccccc2)c1)C1CCCO1 +COc1ccc(-c2cn3c4ccccc4n(N)c3n2)cc1 +Cc1[nH]ncc1C(=O)N1CCC2(CCCCC2)CC1 +Nc1nc(N2CCCC2)ncc1C(=O)NCc1ccccc1 +N#Cc1c(-c2ccccn2)nc2sc(Cc3cccs3)nn12 +COc1ccc(Nc2nc(N(C)C)nc3c2cnn3C)cc1 +O=C(Nc1cccc(Cl)c1)N1CCC(Oc2ncccn2)CC1 +CC(CCc1ccccc1)CC(=O)N(C)Cc1ccccn1 +Nc1nc(N2CCCCC2)nc2ncc3c(c12)CCCC3=O +CCN(CC(F)(F)F)C(=O)c1cccc(C)c1O +COC(=O)c1ncn(CC(=O)C2CCCCC2)n1 +CN1CC(C(=O)Nc2ccc3c(c2)OC(C)(C)O3)CC1=O +O=C(CNC(=O)c1cc2sccn2c1)NCc1ccc(F)cc1 +CC1=C(C(=O)Nc2ccccc2C)C(c2ccncc2)n2nnnc2N1 +Cc1ccc(SCC(=O)NCc2ccccc2C)nc1 +O=C(CCC1OCCCO1)c1ccc2ccccc2c1 +CC(Nc1ccc(Br)cc1)c1nccs1 +CC(NC(=O)Nc1ccccc1)C(=O)Nc1cccc(OC(F)F)c1 +CC(=O)c1cnc(N(C)Cc2cnn(C)c2)s1 +Cc1c(Cl)cccc1NC(=O)c1c(C)c(N)c[nH]c1=O +CC(C)c1n[nH]c(-c2ccccc2NC(=O)c2ccc(F)nc2)n1 +COC(=O)c1cccc(S(=O)(=O)NCc2ncoc2C)c1C +COc1ccccc1-c1cc(NC(=O)C(C)OCC2CC2)[nH]n1 +COCc1ccccc1NC(=O)N(C)CCC(C)C +Cc1cc(C)c(NC(=O)NCc2ncoc2C)c(C)c1 +CCc1nnc(NC(=O)CSc2ncn[nH]2)s1 +Fc1cc(F)c2c(c1)C(CC1CCOCC1)NCC2 +CN(CCC#N)C(=O)CNC(=O)c1c[nH]c2ccccc2c1=O +CN(C)c1ncc(-c2nccn2CCc2ccccn2)cn1 +Cc1cccc(C(N)=O)c1NCc1ccc(SC(=O)N(C)C)cc1 +CC(=O)c1c(-c2ccc(OCC(C)C)cc2)cnn(C)c1=O +C#CCC(OC(=O)CCc1nc(C)no1)c1ccccn1 +Cn1nccc1NC(=O)c1cnc(C2CCCO2)s1 +CC(C)(C(=O)Nc1ccc(C(N)=O)cc1)c1cccc(Cl)c1 +CC(C)(CNC(=O)c1cnc(-c2cccs2)s1)c1ccncc1 +CCN1CCN(C(=O)c2nc3ncc(Br)cn3n2)CC1 +COC1CCN(S(=O)(=O)c2cccc(Cl)c2)CC1 +Cc1cccc(N2CCN(C(=O)CCCn3cccc3)CC2)c1 +CC(NS(C)(=O)=O)C(C)c1ccccc1C(F)(F)F +CNS(=O)(=O)CCC(=O)NC(C)Cc1ccc(C)s1 +CCC1CN(C(=O)c2ccc(=O)n(C)c2)CCN1C(C)C +Cc1nn(C)cc1CN1CCc2cccc(F)c2C1 +CCOCc1nnc(NC(=O)COc2ccc3c(c2)OCO3)s1 +CCN(Cc1cnc2ccccn12)S(=O)(=O)N(C)C +N#Cc1cccc(NC(=O)NCCCNC(=O)c2cccs2)c1 +CCCC1CN(C(=O)Nc2ccc3c(c2)CCCN3C(C)=O)CCO1 +Cc1nnc(NC(=O)c2nn(C)c3ccccc3c2=O)s1 +CC(=O)c1ccc(Cl)c(Cl)c1OCCn1cncn1 +COC(=O)C(NC1CCCCCC1C#N)C(C)C +COC(=O)c1ccc(-c2noc(CCc3ccncc3)n2)cc1 +CCc1ccccc1CNC(=O)Nc1ccc(-c2nnc(C)o2)cc1 +CCCn1c(=O)c2ccccc2n(CC(=O)NC(C)CC)c1=O +COc1ncccc1NCc1ccc2cc[nH]c2c1 +COc1ccccc1CN(Cc1cccnc1)C(=O)C1CCOC1 +Cn1nccc1C(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +COC(=O)CN(C(=O)c1cccc(NC(=O)C(C)(C)C)c1)C(C)C +CCCOCC(=O)Nc1c(-c2ccccc2)nc2ccccn12 +CCCC(C)CC(=O)N=c1[nH]nc2cc(C)ccn12 +COCC1(O)CCN(C(=O)c2cc3nc(C)ccc3o2)CC1 +Cc1ccc(F)c(NC(=O)c2cccc(S(C)(=O)=O)c2)c1 +Cc1cc(C)c(C)c(C(=O)CCC(=O)N(C)C)c1C +CCc1cc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)nc(C)n1 +Cc1nn(C)c(C)c1CCC(=O)NCCCc1nnc2ccccn12 +Cc1csc(C(C)NCc2nnc(-c3cccs3)o2)n1 +CC(=O)Nc1ccc(C#CCNC(=O)c2ccc(F)cc2)cc1 +CC1CN(C(=O)CSc2nccn2C2CC2)CCO1 +CCCn1c(-c2cccc(OC(C)C)c2)ccc(CO)c1=O +O=C(Cc1c(F)cccc1Cl)Nc1ccccn1 +COc1cccc(C(=O)N(C)C(C)c2cc(F)ccc2F)c1 +CCOC(=O)C(C)NC(=O)Cc1ccc(O)cc1 +CCOc1ccccc1OCC(=O)NCC(C)C +Cc1cccc(CN2CCN(C(=O)CCN3CCCC3=O)CC2)c1 +CCc1nc2n(n1)CCCC2NC(=O)N1CCOCC1C1CC1 +Cc1nnsc1C(=O)N1CCN(CC(=O)c2ccco2)CC1 +COc1ccc(CNC(=O)c2cccc(OC(C)=O)c2)cc1 +CCCCN(C)C(=O)c1cc2cc(OC)ccc2oc1=O +O=C(CSc1nncn1-c1ccccc1)NC1CCCC1 +O=S1(=O)N=C(Nc2ccc3c(c2)OCO3)c2ccccc21 +O=C(C1CCC1)N(CC1CCCO1)c1ccncc1 +Cc1nc2c(c(=O)[nH]1)CCN(Cc1cc(C)sc1C)CC2 +COc1ccccc1C(=O)N1CCCN(C(=O)c2cccs2)CC1 +Cc1cc(=O)oc2c3c(ccc12)OCN(Cc1ccncc1)C3 +CCCCNC(=O)C1CCCN(C(=O)c2c(F)cccc2Cl)C1 +CC(C)CN(C)C(=O)C(C)NC(=O)c1ccco1 +O=C(NCc1cccc(-n2cccn2)c1)c1cccc(-n2cnnc2)n1 +O=C1NC2(CCOCC2)Nc2ccc(Cl)cc21 +Cn1nc(C(=O)N2CCCC2)c2c1CN(c1ncc(F)cn1)C2 +CN(C)c1ccc(C(=O)NC2CCCCC2O)cc1 +COc1ccc2nc(SCC(=O)Nc3nc(C)cs3)[nH]c2c1 +COC(=O)c1cc(C)ccc1S(=O)(=O)C(C)C +CC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccc(C#N)cc2)cc1 +Cn1cc(NC(=O)c2ccc(Cl)c3cccnc23)cn1 +CC(C)(CO)NC(=O)COc1ccc(F)c(F)c1 +Cc1ccc(=O)n(CC(=O)N2CCC(C)CC2C)n1 +Cc1ccsc1CNc1ccc(S(N)(=O)=O)cc1 +Cc1nc(-c2cc(C(=O)NCc3ccncc3)n(C)c2)cs1 +Cc1ccc(O)c(C(=O)NCc2cnn(C)c2C)c1 +O=C(Cn1cc(CO)c2ccccc21)N1CCOCC1 +CN1CCOc2ccc(NC(=O)CCCc3ccccc3)cc2C1=O +CC(NC(=O)c1cccnc1SC(F)F)c1nc2ccccc2[nH]1 +CNS(=O)(=O)c1ccc(Cl)c(C(=O)Nc2ccccc2C)c1 +Cc1nc2nnc(C(=O)Nc3ccccc3Cl)c(C)n2n1 +COCC(NC(=O)Cc1coc(-c2ccc(Cl)cc2)n1)C(N)=O +Cc1occc1-c1nnc2ccc(Br)cn12 +O=c1nc2c3ccccc3ncn2nc1-c1cccs1 +CCC(C)NC(=O)c1ccc(CN2CCOCC2)cc1 +CCOC(=O)C1=C(C)C(C(=O)Nc2ccc(=O)n(CC)c2)=NC1C +N#Cc1cccc(NC(=O)c2cccc(NC(=O)NC3CCCC3)c2)c1 +O=C(CCc1ccccc1)NCC#Cc1ccc(N2CCOC2=O)cc1 +NC(=O)Nc1cccc(NC(=O)c2cccc3[nH]ccc23)c1 +Cc1cc(F)c(S(=O)(=O)N(C)Cc2ccccn2)cc1F +Cc1ccc(SC(C)C(=O)N2CCC(C(N)=O)CC2)cc1 +CCc1nc(C)cn1S(=O)(=O)c1cc(Cl)ccc1OC +CCc1onc(C)c1NC(=O)C1CC1C(=O)OC +Cc1cnc(N2CCC3C2CCN3c2ncccn2)nc1 +CCCCn1c(=O)c2c(nc(-n3nc(C)c(C)c3C)n2C)n(C)c1=O +CCc1nc(CNC(=O)c2scnc2C2CC2)cs1 +CC(=O)N1CCc2cc(NC(=O)CNc3cccc(C)c3C)ccc21 +N#CCc1ccc(OCC(O)Cn2nc(-c3ccco3)oc2=O)cc1 +N#Cc1csc(CN2CCN(CC(=O)NC3CCCCC3)CC2)c1 +Cn1cc(CNC(=O)NCC2(O)CCCC2)c(-c2ccccc2)n1 +COCc1ncn2c1CN(C(=O)c1ccccc1C)CC2 +COc1ccc(C(O)CNC(=O)c2cccc(F)c2)cc1 +O=C(c1csc(-c2ccsc2)n1)N1CCOC2CCCCC21 +Cc1cnn(CC2CCCCN2C(=O)c2c(C)noc2C)c1 +C=CCS(=O)(=O)c1ccc(F)c2ccccc12 +CC(NC(=O)C(C)(C)C)C(=O)NCCCc1nc2ccccc2s1 +CC(=O)N1CCc2sc(C(=O)N3CCCC3)cc2C1 +CC1CN(C(C)(C)CNC(=O)N2CCOCC2C2CC2)CC(C)O1 +COC(=O)c1cc(-c2ccc(C)cc2)nc2c1c(C)nn2C +CCC(C)NC(=O)CN1C=NS(=O)(=O)c2ccccc21 +CCOC(=O)CCC(C)NC(=O)c1ccc2nncn2c1 +CCCNC(=O)N1CCCC(NS(C)(=O)=O)C1 +Nc1nc(C(=O)N2CCN(CC(F)(F)F)CC2)n[nH]1 +CN(CC(=O)N1CCCC1)C(=O)c1cccnc1OCC(F)(F)F +CCc1cnc(CCNC(=O)NC2Cc3ccccc3C2)s1 +CN(CCNC(=O)C1(c2ccccc2F)CC1)S(C)(=O)=O +O=C(Cc1ccsc1)NC1CCc2cc(Cl)ccc21 +COc1ccc(OCC(=O)NCc2cc(-c3ccccc3)no2)cc1 +Cc1ccc2ncc(C(=O)N3CCC(C(F)(F)F)CC3)n2c1 +CS(=O)(=O)Nc1ccc(C(=O)N2CCOCC2)cc1 +N#CCCSc1nc2scc(-c3ccco3)c2c(=O)[nH]1 +COc1ccc(-c2nnc(NC(=O)c3cc(C)on3)s2)cc1 +Cc1csc(NC(=O)c2csc(Nc3ncccn3)n2)n1 +Cc1cc(C)c(CCSc2nnc(C)c(=O)n2N)c(C)c1 +CCc1ccc(C(=O)Nc2cccc(C(=O)NC)c2)cc1 +Cc1nc2ncc(-c3cccc(N(C)C)c3)cc2[nH]1 +CCOc1ccc(CNC(=O)c2cnc(CC)nc2C)cc1 +COC(=O)c1ccc(N2CCN(C(=O)CCC(F)(F)F)CC2)cc1 +O=C(NCc1cccnc1)c1ccc(-c2ccccc2F)o1 +Cc1ccc(F)c(OCC(=O)Nc2ccccc2N2CCCC2=O)c1 +CC1CCCN(C(=O)CN(C)c2ccc(F)c(F)c2)C1 +COc1ccc(OC)c(CCc2nc(C(C)(C)NC(C)=O)no2)c1 +Cc1ccc(C(=O)N2CCCCC2CCc2ccccc2)cn1 +Cc1nc(Cn2c(C)csc2=O)nc2ccccc12 +Nc1nc(NCCc2ccccc2)nc(-c2ccccc2O)n1 +CC(NC(=O)c1csnn1)c1cccc(C(F)(F)F)c1 +NC(=O)c1ccc(C(=O)NCc2ccccc2F)cn1 +Cc1ccccc1CNC(=O)CCn1c(=O)oc2ccccc21 +CC(C)C(NC(=O)c1n[nH]c(=O)[nH]1)c1ccccc1Cl +Cc1cccc(NC(=O)Cc2nc(-c3ccccc3)n[nH]2)c1C +Cc1ccccc1-n1c2c(cc(C#N)c1=O)C(=O)CC(C)(C)C2 +COC(=O)CSc1nncn1-c1ccc(C)cc1C +Cc1sc(NC(=O)C2CCCO2)c(C#N)c1C +CCN(Cc1cnc(C2CCC2)s1)C(C)c1cccc(O)c1 +Cc1cc(C)nc(Sc2ccc(C(=O)NC(C)(C)C)cc2)n1 +Nc1cccc(NC(=O)CCCCn2ccc(=O)cc2)c1 +CCCNC(=O)c1ccccc1NC(=O)c1ccc(=O)n(C)n1 +O=C(c1cccc(-n2cccc2)c1)N1CCOCC1C1CC1 +COc1ccc(C(=O)NCC(C)(C)c2cccc(F)c2)nn1 +CCCOC(=O)C1CCN(C(=O)N2CCCC2)CC1 +COc1cccc(CNC(=O)c2ccc(O)c(Cl)c2)c1OC +COc1ccc(C)cc1S(=O)(=O)N1CCCCC1CCO +Cc1noc(C2CCN(C(=O)c3scnc3C)CC2)n1 +CC(=O)N1CCc2cc(S(=O)(=O)N3CCN4CCCC4C3)ccc21 +Cc1ccc(C(=O)N2CCOc3c(N)cccc32)cc1 +COc1ccc(C(=O)OCC(=O)N2CCCCC2)c(OC)c1OC +COc1ccccc1C(=O)N1CCC(OCc2ccccc2F)CC1 +CC(C)=CCS(=O)(=O)c1nnc(C(C)C)n1C1CC1 +O=C(NCCCN1CCCC1=O)Nc1ccc(OC(F)F)c(F)c1 +COCC(=O)N(Cc1ccco1)Cc1cc2ccc(C)cc2[nH]c1=O +Cc1oc2ncn(C)c(=O)c2c1C(=O)N1CCc2cc(F)ccc2C1 +Cc1n[nH]c(-c2cccc(CNC(=O)COc3ccccc3F)c2)n1 +O=C(NC1CCCC1)c1cccc(Br)c1 +CC(C)CCn1cccc(C(=O)N(C)C(C)C2CC2)c1=O +COCCC(C)NC(=O)c1ccc(S(N)(=O)=O)c(C)c1 +CC(=O)N1CCN(C(=O)CCCc2nc3ccccc3c(=O)[nH]2)CC1 +COc1ccnc(NC(=O)CN(C)C(=O)c2ccccc2)c1 +CC1CCN(C(=O)Cn2c(C(F)(F)F)nc3ccccc32)CC1 +Cc1c(C(=O)Nc2ccn(Cc3ccccc3)n2)cnn1C +C=CCCOC(C)C(=O)N1CCN(C(=O)CO)CC1 +CCc1noc(CN(C)C(=O)c2snnc2CC)n1 +COCCn1cnnc1C1(C)CCCN(S(C)(=O)=O)C1 +CCN1CC(C(=O)NC2CCN(S(C)(=O)=O)CC2)CC1=O +N#Cc1ccsc1C(=O)N1CCc2ccc(Cl)cc2C1 +CCc1ccccc1CNC(=O)NCc1ccnc(-n2cccn2)c1 +N#Cc1nccnc1Oc1ccc(Cl)cc1Cl +O=C1CN(C(=O)CN2CCCCC2=O)CCN1CCc1ccccc1 +O=C(NCCC1CCN(CC(F)(F)F)CC1)c1ccc(O)cc1F +CCN(Cc1ccc(OC)cc1)C(=O)c1cc(OC)ccc1O +CN1CCc2c(sc3c2c(NCCO)nc2nnnn23)C1 +CCN1CC(C(=O)NC(C)(C)CC(C)(C)C)CC1=O +COc1ccccc1NC(=O)c1cc2ccncc2cn1 +CCOc1ccc(CC(=O)OCn2nnc3ccccc3c2=O)cc1 +CC1CCN(C(=O)Cc2nc(CO)cs2)CC1 +Cc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1S(C)(=O)=O +CCOc1c(Cl)cccc1NC(=O)NCc1ccsc1 +COc1ccccc1CN(CCO)C(=O)c1ccccc1C#N +CCCC(C#N)NS(=O)(=O)c1c(CC)nn(C)c1CC +CCc1noc(CN(C)Cc2cc(Br)c(OC)s2)n1 +Cc1c(C(=O)NCc2ccccc2)oc2c1C(=O)CC(C)(C)C2 +CCCc1cc(C(=O)NCCS(=O)(=O)N2CCCC2)n(C)n1 +CN(Cc1cscn1)S(=O)(=O)c1ccc(F)cc1N +Cn1nnnc1SC1CCCN(c2cccc(F)c2)C1=O +CC(NC(=O)NCCCN(C)S(C)(=O)=O)c1ccc(C#N)cc1 +CSc1ccccc1C(=O)NCC(O)c1ccc(C)o1 +CCOc1ccc(Cn2c(=O)oc3ccccc32)nc1 +CC(=O)c1c(C)nc(C)nc1SCCOc1ccc(C#N)cc1 +CCc1cc(-c2ccc(C(=O)NC)c(N)n2)ccc1OC +CC(Sc1nnc(CO)n1C1CC1)C(=O)N(C)Cc1ccccc1 +CC(C)CN1CCOC(CCNC(=O)c2ccc[nH]2)C1 +Cn1c(C2CC(=O)N(C(C)(C)C)C2)nc2ccccc21 +CC(O)C1NC(=O)C(Cc2ccc(O)cc2)NC1=O +CC(NC(=O)Cn1c(=O)c(C#N)cn(C)c1=O)c1ccco1 +Cc1cc(C)n(CCNC(=O)c2nnc3ccc(Cl)cc3n2)n1 +Cc1ccc(CNC(=O)C(C)S(=O)(=O)c2ccccc2C)cc1 +O=C(Cc1nnc(-c2ccccc2)o1)NCc1ccccc1Cl +CSc1cccc(NC(=O)COc2ccc3ccc(=O)oc3c2)c1 +COc1cc(C(=O)N2CCCC(C(N)=O)C2)ccc1OC1CCCC1 +COc1cccc(-n2nc(C)c(C3COCCN3C(N)=O)c2C)c1 +NC(=O)C1CCCN1c1ccc(-c2nc(Cc3ccccc3)no2)cn1 +Cn1cc(C2CCCN2C(=O)CCCOc2ccc(Cl)cc2)cn1 +CCN(CC(=O)NC(C)(C#N)C1CC1)c1ccccc1 +Cc1ccc(CC2Oc3cc(O)ccc3N(CC(N)=O)C2=O)cc1 +CC(C)(C)c1cnc(Cn2cc(C(N)=O)nc2C2CC2)o1 +CNc1nc(-c2cc(-c3cccnc3)nn(C)c2=O)cs1 +Cc1nc(-c2ccccc2)sc1C(C)NC(=O)c1cnn(C)c1C +CCOC(=O)C1=C(N)Oc2cc(N)ccc2C1c1ccc(OC)cc1 +COCCOc1cc(Br)ccc1OC +CC(=O)c1ccc(NC(=O)N(CCc2nccs2)C(C)C)cc1C +CN(C)c1ccc(C(=O)OCc2nc(N)c3ccccc3n2)cc1 +CCc1ccsc1C(=O)Nc1ccc(CN2CCCC2=O)cc1 +Cc1c(C(=O)NC2CCc3nnc(C)n3C2)oc2c(F)cccc12 +CCCC1CN(C(=O)CSc2ccccc2)CCO1 +Cc1c(CCC(=O)N2CCC(Oc3cccc(Cl)c3)C2)cnn1C +CC(C)c1ccccc1OC(=O)C1CCN(c2cnccn2)CC1 +Cc1cc(NC(=O)CSc2nnc(-c3ccoc3C)n2N)no1 +COc1ccc(F)cc1NC(=O)N(C)Cc1nccn1C(F)F +COC(=O)c1ccccc1NC(=O)CCC(C)O +CC(OC(=O)c1cc(F)c(F)cc1N)C(=O)N1CCOCC1 +CC(C#N)Sc1nnc(-c2ccncc2)n1-c1ccc(Cl)cc1 +CCC(=O)Nc1cccc(C(=O)Nc2cccnc2-n2ccnc2C)c1 +CC(C)C1CN(c2cnccn2)CCC(=O)N1CC1CC1 +COc1ccc(-c2ccc3c(c2)OCCO3)cc1N +COc1ccc(CNC(=O)c2n[nH]cc2Cl)cc1 +Cc1cc(CN(C)c2ncnc3sc4c(c23)CCC4)no1 +O=C(CC1Sc2ccccc2NC1=O)OCC#Cc1ccccc1 +Cc1noc(NC(=O)c2cccc(Br)c2)n1 +COCc1ccccc1C(=O)NCc1ccccc1N1CCOCC1 +CC(Sc1ncn[nH]1)C(=O)Nc1ccc(F)c(Cl)c1 +COC(=O)CC1CCN(C(=O)c2cc3ccccc3n2C)CC1 +CCNC(=O)CNC(=O)Nc1c(C)cccc1CC +COc1ccc(OC)c(NC(=O)c2ccc3c(c2)nnn3C(C)C)c1 +CNc1cc(S(=O)(=O)N2CCC(C)CC2)ccn1 +CC(C)Oc1nc(OC(C)C)nc(OC(C)C)n1 +O=C(NCc1ccccc1Cn1cncn1)NC1CCC(O)CC1 +CC1CC(Sc2nnnn2C2CCCC2)C(=O)O1 +Cc1cn2nc(N3CCC(NC(=O)c4cc(C)on4)CC3)sc2n1 +c1ccc2c(c1)CN(Cc1nc(C3CCOC3)no1)CCO2 +N#CCn1c(CN2CCCC2Cn2cncn2)nc2ccccc2c1=O +Cc1ccc2cnn(C(=O)Nc3ccc4c(c3)OCCO4)c2c1 +Cc1[nH]c2c(C)cc(Cl)cc2c(=O)c1CCC#N +Cn1c(=O)c2c(ncn2CC(=O)NCCCn2cccn2)n(C)c1=O +Cc1cccc(CNC(=O)NC2CCN(c3ccccc3)CC2)n1 +CC(=O)Nc1cccc(CNC(=O)Nc2nc(C)cs2)c1 +FC(F)(F)COc1cc(Cl)ccc1NCc1nnc(C2CC2)o1 +Cc1ccc(-n2ccnc2)c(C(=O)Nc2ccc(-n3ccnc3)cc2)c1 +NC(=O)c1ccccc1OCc1ccn(-c2ccccc2)n1 +CC(C(=O)NCc1ccccc1)N(c1ccccc1)S(C)(=O)=O +CC(C)C(C#N)C(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1noc(C)c1CCC(=O)OCc1cc(-c2ccco2)on1 +COc1cccc2cc(C(C)NCCc3nc(C)no3)oc12 +CC1CC1C(=O)Nc1cccc(C(=O)Nc2c[nH]ccc2=O)c1 +N#Cc1ccc(NC(=O)COc2cccc(Cl)c2)cc1 +CCC(C(=O)NC(C)(C)C)N(c1ccc(C)c(C)c1)S(C)(=O)=O +CC(CC1CCCC1)C(=O)NC(C)c1ccncc1 +O=C(Cc1c[nH]c2cc(Cl)ccc12)N1CCOCC1C1CC1 +CN(C)S(=O)(=O)NCC#Cc1ccccc1F +COc1ccc(Cl)cc1CNc1cc(C(N)=O)ccc1F +Cc1cc(C(=O)NC2CCCc3c2cnn3Cc2ccccc2)on1 +CCc1ccccc1NC(=O)Cn1cc(N)ccc1=O +CCC(C(=O)OCC(=O)Nc1ccccc1C#N)c1ccccc1 +Cc1ccccc1CN(C)C(=O)CN(C)CCC#N +CCOCC1CCCN(C(=O)c2cccc(C(=O)N(C)CC)c2)C1 +Cc1ccccc1CN(C)C(=O)Nc1ccccc1OCCC(N)=O +O=C(NCC1CN2CCCCC2CO1)Nc1ccc(F)cc1F +N#Cc1ccc(CN2CCOC(c3ccsc3)C2)cc1 +COc1ccc(-c2c(CO)nnn2CCO)cc1OC +O=C(Nc1ccc2c(c1)Cc1ccccc1-2)c1cnccn1 +Cc1ccc2c(c1)C(CC(N)=O)CC1(CCCCC1)O2 +COCCCC1CCCN(C(=O)c2ccc3sccc3c2)C1 +CNC(=O)c1cccc(C(F)(F)F)c1OC1CC1 +COc1ccc(NC(=O)NCC2(C)COC2)cc1NC(C)=O +COc1ccccc1NC1CCN(C(=O)NCc2noc(C)n2)CC1 +Cc1cccc(OCC(=O)Nc2ccccc2-n2cnnn2)c1 +Cc1noc(C)c1CN(C)C(=O)NCc1ccc(F)c(Cl)c1 +CCCCNC(=O)C1CCN(C(=O)c2cccc(Cl)c2)CC1 +CCc1nc(CNc2ccc(-c3nccs3)cc2)cs1 +CCCNC(=O)CCNC(=O)c1cc(-c2ccc(F)cc2)c(C)s1 +COc1cccc(C(=O)N(Cc2cccnc2)c2ccc(F)cc2)c1 +Cc1ccccc1C(C#N)CCC(=O)N1CCOCC1 +CC(C)c1cccc(N(C)C(=O)Cc2ccc(S(N)(=O)=O)cc2)c1 +CCOc1ccc(CC(=O)N2CCC(O)CC2)cc1C +Nc1ccc(-c2csc(NC(=O)C3CCCC3)n2)cc1 +CCOc1ccccc1-c1ccc(N)c(=O)n1CC(C)C +COc1cc(CNC(=O)c2csc(Cc3ccccc3)n2)ccn1 +Cc1cc(C)n(CC(C)CNC(=O)N(C)Cc2c(C)noc2C)n1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)Nc1cc(F)cc(F)c1 +COc1ccc(S(=O)(=O)N(C)Cc2ccc(C)o2)cc1F +O=C(CNc1cc(-n2cnnn2)ccc1F)NCc1ccccc1 +Cc1csc(SC(C)C(=O)N(C)c2ccccc2)n1 +Nc1ccc2c(c1)sc1nc(-c3ccncc3)cn12 +Cc1cc(Br)cc(N)c1NC(=O)c1cccs1 +CCc1ccc2nc(NC(=O)c3nccnc3N)sc2c1 +Cc1cc(N2CCN(C(=O)C3CC=CC3)CC2)nc(C(C)C)n1 +COc1ccc(-c2nc3sc(C4CC4)nn3c2C#N)cc1OC +CC(C)(C)c1nc(CNC(=O)N2CCCC2)cs1 +O=C1N(CC2CCC2)CCCC12CCN(c1ncnc3[nH]ccc13)C2 +CC(C)(C)n1cc(C(=O)NC(c2ccccc2)c2ccncc2)cn1 +O=C(Nc1ccc(OCCO)cc1)c1ccn(C2CCCC2)n1 +Cc1cc2nc(CN(C)c3nccc(-c4ccncc4)n3)[nH]c2cc1C +O=C(Cn1cnc2sccc2c1=O)OCc1nccs1 +CCOC(=O)c1cnn(-c2ccc(Br)cc2)c1C +COCCn1ccc2nc(C)c(C(=O)N3CCCCCC3)cc2c1=O +COCCNC(=O)Nc1ccc(C(=O)NC2CCCC2)cc1 +O=C(NCc1ccccc1F)c1ccccc1-n1cnnn1 +Nc1ccc(S(=O)(=O)NS(=O)(=O)c2ccccc2)cc1 +CC(C)C(C)(C#N)NC(=O)Cn1ncnc1-c1ccccc1Cl +O=C(CC1CC1)Nc1cccc(Oc2cccnn2)c1 +c1ccc(CCc2noc(COc3ccc4cnoc4c3)n2)cc1 +NC(=O)C1(NC(=O)Cn2cnnn2)CCCCC1 +CC(C)c1nc(CNC(=O)Cc2csc(-c3ccccc3)n2)no1 +COc1ccccc1CC(=O)NC1CCN(c2c(F)cccc2F)C1 +CCCC1CN(C(=O)CCNC(=O)c2ccsc2)CCO1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(C(C)C)cc1 +O=C(c1ccccc1)c1nccn1CC(O)CN1CCOCC1 +CCc1cc(NC(=O)NCCOc2ccc(Cl)cn2)n(C)n1 +COc1cc2c(cc1F)CCNC2c1cccc(C#N)c1 +CCOc1cc(-c2ccccc2)cn(CCCO)c1=O +Cc1noc(NC(=O)CCc2ccc(C#N)cc2)n1 +CN(Cc1ccco1)C(=O)c1cc2c(=O)c3ccccc3oc2o1 +O=C1CCSc2ccc(S(=O)(=O)N3CCCCC3)cc2N1 +COc1ccc(CNC(=O)N2CC(C)C(C)(O)C2)cc1 +CC(OCC1CCCCO1)C(=O)Nc1c2c(nn1C)CCC2 +Cc1cc(NC(=O)Cn2c(C)cc3ccccc32)n(-c2ccccc2)n1 +O=C(c1ccncc1)N1CC2CCC(C1)N(C(=O)C1CCCC1)C2 +CC(NC(=O)CCn1cncn1)c1csc2ccccc12 +Cc1c(NC(=O)NC(C)Cn2cncn2)cccc1OC1CCCC1 +Cn1cc(-c2noc(C=Cc3ccc4c(c3)OCO4)n2)ccc1=O +Cc1ccc(F)cc1NC(=O)NCc1cccnc1 +O=C(Cn1cnnn1)N(Cc1ccncc1)C1CC1 +Cc1ccncc1NC(=O)N1CCOC(c2cnn(C)c2)C1 +COCCOc1ncccc1C(=O)OC1CCCC(C)C1 +COc1ccc(S(=O)(=O)NCc2nnc3ccccn23)cc1 +CC(C)n1cnnc1SCc1nnc(-c2ccc(Cl)cc2)o1 +COc1cccc(C2(O)CCCCC2O)c1OC +Cc1cnc(CC2COCCN(S(C)(=O)=O)C2)cn1 +Cc1noc(C)c1N(C)C(=O)CCCn1ccc2cc(Cl)ccc21 +CC(C)c1ncc(CN(C)CCN2CCCC2=O)s1 +COc1cccc(-c2nnn(-c3ccc(C)cc3)c2N)c1 +O=C(CCCOc1cccc(F)c1)N1CCN(CCO)CC1 +COC(=O)NCC(=O)Nc1ccccc1OC(C)C +CNC(=O)Nc1ccc(NC(=O)c2ccnc(-n3cncn3)c2)cc1 +Cc1nc2c(C#N)cnn2c(C)c1CCC(=O)NCCC(=O)N(C)C +Cc1cc2nc(C(=O)Nc3ccc(Cl)cc3F)cc(C)n2n1 +NS(=O)(=O)c1cccc(NC(=O)c2cc3ccccc3oc2=O)c1 +CCN(C(=O)COc1ccc(C#N)cc1OC)c1ccccc1 +CCn1nc(C)c(CCC(=O)NCc2ccc(F)cc2)c1C +CC1(C)Cc2c(sc(NC(=O)N3CCOCC3)c2C#N)CO1 +CC(C)=CCC1(CO)CCCN(C(=O)c2cccc(CO)n2)C1 +CCCCSc1ccc(NC(=O)c2nc[nH]n2)cc1 +CCc1ccc(C(=O)C(C)Sc2nc(N)c(C#N)cc2C#N)cc1 +CNC(=O)c1ccccc1-c1nc(-c2ccccc2)no1 +O=C(c1ccccc1N1CCOCC1)N1CCCC(n2cccn2)C1 +O=C(NCc1ccncc1)C1CCN(c2cccc(Cl)c2)C1=O +CC(C)OCCOC(=O)c1csc(-c2ccsc2)n1 +CC(C)C(=O)Nc1ccc(OS(=O)(=O)c2cccs2)cc1 +CN(C)C(=O)c1ccc(C(=O)NCc2ccc(-n3cccn3)cc2)cc1 +O=c1[nH]ccn(-c2ccc(OCc3ccccc3)cc2)c1=O +CCOc1ccc(NC(C)=O)cc1S(=O)(=O)NCc1ccco1 +CCn1c(C(=O)Nc2ccn(C)n2)cc2sccc21 +NC(=O)c1ccccc1NC(=O)CNc1ccc(Br)cc1 +CCCC(=O)N1CCCC(C(=O)NC(C)C(C)CC)C1 +CCCN(C)C(=O)c1cc(C)ccc1NS(C)(=O)=O +N#Cc1c(-c2ccncc2)nc2sc(-c3ccccc3F)nn12 +O=S(=O)(NCc1csc(-c2cccs2)n1)c1ccccc1 +CNc1cncc(C2CCCN(c3cnccn3)C2)n1 +COc1cccc(CNC(=O)c2ccc(N(C)C)nc2)c1 +CNC(=O)C(NC)c1c(OC)cc(OC)cc1OC +N#Cc1ccc(NCc2ccc(N3CCCC3=O)cc2)nc1 +CC(C(=O)N1CCCc2ccccc21)N1CCn2c(nn(C)c2=O)C1 +Cn1c(C(=O)NC(C)(C)C)nnc1-c1cccnc1 +Cc1cccc(-n2nnnc2-c2ccc(C)c(N)c2)c1 +O=c1cc(-c2ccc(S(=O)(=O)N3CCCC3)cc2)cc[nH]1 +CCN(CC)C(=O)c1cccc(Oc2ccc(C)nn2)c1 +CCCOc1cccc(CN2CCOC(C(N)=O)C2)c1 +Cc1cc(C)n(CCCNC(=O)N2CCc3ccc(Cl)cc3C2)n1 +CC(C)CNC(=O)CC(C#N)c1ccccc1Br +CC(C)COCCCNC(=O)NC1CCC(O)CC1 +CCOc1ccc(C(=O)NC2C3CCOC3C2(C)C)cc1 +CCc1c(C(=O)Nc2ccc3nc(C)cn3c2)cnc2cc(O)nn12 +N#Cc1cccc(NC(=O)C2CCN(C(=O)C3CC3)CC2)c1 +CCC(=O)N1CCCC(OCc2ccc(Br)cc2)C1 +Cc1ccc(F)c(NC(=O)C2CCCN(S(C)(=O)=O)C2)c1 +Cc1ccc(NC(=O)CCNC(=O)NCc2ccccn2)nc1 +CC(C)c1noc(CCNCc2cnc(C(C)(C)C)s2)n1 +Cc1noc(C)c1CC(C)NC(=O)Nc1ccc(Cl)c(F)c1 +OCCn1ncc2c(N3CCCC3c3ccc(F)cc3)ncnc21 +Cc1csc(=O)n1CC(=O)N1CCOCC1C1CC1 +Cc1oc(C(C)C)cc1C(=O)N(C)Cc1ncc[nH]1 +CC(C)COCCCNC(=O)c1cn2cccnc2n1 +COC(C)(C)c1noc(CCN2C(=O)C(C)Oc3ccccc32)n1 +Cc1ccc(C(=O)c2c[nH]c3cc4c(cc3c2=O)OCO4)cc1 +CCn1c(C)cc(C(=O)NCc2ccc(OC)c(OC)c2OC)c1C +O=C1CCCCN1CSc1nnc(NCc2ccccc2)s1 +COc1cc(C(=O)NCc2ccc(C#N)cc2)cc(OC)c1C +Cn1cc2ccc(F)c(C(O)c3ccccc3)c2n1 +Cc1noc2nc(C3CC3)cc(C(=O)N(C3CCCC3)C3CC3)c12 +C#CCN(c1nccs1)S(=O)(=O)Cc1ccccc1 +O=C(Nc1cc(F)cc(F)c1)N1CCC(Oc2ccccc2)CC1 +CC(=O)c1ccc(NC(=O)C2CC(=O)OC23CCCCC3)cc1 +CCSc1ccccc1NC(=O)CSc1nnc(C)n1N +CCSc1cc(C(=O)Nc2ccc(C)cc2O)ccn1 +CCC(CC)NC(=O)C(C)n1cnc2c1c(=O)n(C)c(=O)n2C +Cc1noc(C)c1C(=O)NCc1ccc(Cn2ccccc2=O)cc1 +CC(C)n1cnnc1SCc1cccc(F)c1F +CCN1CC(C(=O)NC(C)(C)C(=O)OC)CC1=O +Cc1cc(Cl)ccc1NS(=O)(=O)c1ccc(=O)[nH]c1 +CCc1c(-c2ccncc2)n[nH]c1NC(=O)C(C)OC +CCOC(=O)C1CCN(C(=O)C(C)NC(=O)c2ccco2)CC1 +COc1cc(N)ccc1NC(=O)CN1CCc2ccccc21 +c1ccc2c(c1)OCC(CNCc1cncnc1)O2 +CCCc1nnc(NC(=O)N2CCOC(c3ccc(C)o3)C2)s1 +CC(CC(=O)OCc1ccc2c(c1)OCO2)c1cccnc1 +COc1cccc(C(=O)N2CC(C)CC(C)C2)c1OC +Nc1cccc(OCCCn2nncc2-c2cccs2)c1 +Cc1cccnc1NC(=O)c1occc1COc1ccccc1 +CS(=O)(=O)N1CCCC12CCCN(C(=O)CO)C2 +O=C(Nc1ccc2cn[nH]c2c1)c1c(F)cccc1Cl +Cc1ccc(NC(=O)c2ccc3ncccc3c2)c(C)c1O +COC(CNC(=O)N1CCC(C)(CO)CC1)c1ccccc1Cl +CNC(=O)c1cccc(S(=O)(=O)Cc2ccccc2)c1 +C#CCNC(=O)NCC1CCN(c2ccccc2)C1 +CCOc1ccc2nc(C(=O)NCc3cccc(C)c3)cn2n1 +CCOC(=O)c1ccc(S(=O)(=O)NC(C)C(C)C)cc1 +CS(=O)(=O)N(CC(N)=O)c1cc(C(F)(F)F)ccc1Cl +CCNC(=O)Nc1cccc(NC(=O)c2ccc(F)nc2)c1 +O=C(NCCC(O)c1cccs1)c1ccsc1 +CCCc1cc(CNC(=O)C2Cc3cc(Cl)ccc3O2)on1 +Cc1cc(NC(=O)N2CCOC3(CCOCC3)C2)c2ncccc2c1 +CCCCN(CCC(=O)N1CCNCC1)C(=O)c1ccc(C)cc1 +CCOCCC(=O)Nc1cc(OC)ccc1Cl +COc1ccc(F)c(NC(=O)c2c[nH]nc2-c2ccccc2)c1 +c1ccc2c(c1)ncn2-c1ccc(-c2noc(-c3cnccn3)n2)cn1 +CC(O)CNC(=O)CC12CC3CC(CC(Br)(C3)C1)C2 +CCN(C(=O)C1CSc2nccc(=O)n2C1)c1ccccc1C +Cc1ccc(C)c(S(=O)(=O)CC(=O)N(C)CC(F)(F)F)c1 +CCc1nnc(C(=O)Nc2cccc(C(=O)NC3CCCC3)c2)s1 +CC(Cc1ccc(O)cc1)NC(=O)c1scnc1C1CC1 +COc1ccc(OC(=O)c2ccc(OC)nn2)cc1 +O=C(Nc1cccc(CO)c1)c1cc(F)ccc1F +CCOC(=O)CC1NCCc2cc(OC)c(O)c(Cl)c21 +CCC(CC)(CC)NC(=O)c1cc(OC)c(S(N)(=O)=O)s1 +CCCCc1nc(C)sc1C(=O)N=c1[nH]cc[nH]1 +Cn1ccc2c(C(=O)OCCCc3cccnc3)cccc21 +CC(C)(C)c1ccccc1NCC(=O)N1CCCC(C(N)=O)C1 +O=C(CCc1ccco1)N1CCC(C(O)c2ccc(Cl)cc2)CC1 +CN(CC1CC1)C(=O)Nc1ccc(OCC(N)=O)cc1 +CCC(NC(=O)c1ccc(F)cc1F)c1ccc(OC)cc1 +CCn1cc(NC(=O)C2CCN(C(=O)c3ccccc3C)CC2)cn1 +CC(=O)Nc1ccc(F)c(C(=O)OCc2nc3ccccc3[nH]2)c1 +COCC(C)NC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +CC(=O)N1CCN(Cc2ccc(OCc3ccc(F)cc3)cc2)CC1 +CC(C)=CC1C(C(=O)N2CCN(C(=O)Cn3cnnn3)CC2)C1(C)C +CCCOCCC(=O)Nc1nc2ccc(N)cc2s1 +CCOc1ccc(NS(=O)(=O)c2ccc3c(c2)C(=O)NC3)cc1 +CN(C(=O)Cc1cc2ccccc2[nH]c1=O)C1CC1 +Cc1nnc(SCC(=O)NC(C)c2ccccc2)s1 +NS(=O)(=O)c1ccc(CNC(=O)c2ccccc2O)cc1 +CC(Oc1cccc(Cl)c1Cl)C(=O)NCCNC(=O)C1CC1 +Cc1cc(C(=O)Nc2ccc(Cl)c(C(=O)NC3CC3)c2)c(C)o1 +CN1C(=O)CCOc2ccc(C(=O)C3CCC3)cc21 +CC(C)OC(=O)Cn1nc(-c2ccccc2F)ccc1=O +O=C(Nc1cccc(N2CCOC2=O)c1)c1cnccn1 +CN(C1CCCCC1)S(=O)(=O)NC1CCC2(CC1)OCCO2 +OCCn1c(CC(F)(F)F)nc2ccc(F)c(F)c21 +Cc1cc(S(=O)(=O)Nc2cccc(-c3cn[nH]c3)c2)c(F)cc1F +CCCOc1ccc(C(C)=O)cc1NC(=O)COC +CNC(=O)c1cccc(NC(=O)c2ccc(C)s2)c1 +O=C(NCC1CC=CCC1)c1c[nH]c2cccc(F)c12 +CC(NC(=O)c1ccco1)c1nc(-c2ccncc2)n[nH]1 +CC(=O)N1CCCn2nc(CNc3ncnc4ccsc34)cc2C1 +CCn1cnnc1CNC(=O)c1cc(Cl)c2c(c1)OCCO2 +Cc1cc(NC(=O)C(C)OC(=O)c2nc3nccc(C)n3n2)no1 +Cc1c(CN(Cc2cccnc2)CC2CCCO2)cc(C#N)n1C +COCCCNC(=O)CNc1ccccc1Cl +CCN(CC)C(=O)Cn1c(CC(C)C)nc2c(N)cccc21 +COCC1CCCN1C(=O)c1cc(CC(C)C)nn1C +CCOCc1ccc(NC(=O)N2CCCC2CN2CCOCC2)cc1 +CC1CN(C(=O)c2ccc(OC(F)F)cc2)CC(C)O1 +O=C(CCn1ccccc1=O)NC(c1ccc(Cl)cc1)C1CC1 +CCCC(=O)c1ccc2c(c1)N(C(C)C(=O)OC)C(=O)CO2 +C#CCNC(=O)NCCS(=O)(=O)NCc1ccccc1 +O=C(Nc1ccc2c(c1)COC2)NC1CCCOc2ccccc21 +CC(=O)N1CCCC(C(=O)NCC(C)(C)c2ccc3c(c2)OCO3)C1 +CCCN(CCC)S(=O)(=O)c1ccc(OC)cc1 +Cc1ccccc1C1(CNC(=O)NCC(F)(F)F)CCOCC1 +COC(=O)N1CCC(NS(=O)(=O)c2ccc(F)cc2F)CC1 +CCC(=O)Nc1cccc(NCc2cccc(OC)c2)c1 +COc1ccc(F)cc1C(=O)Nc1ccnn1CC(C)C +COCCOc1cccc(NCc2cccc(O)c2)c1 +Cc1ccc2ncc(C(=O)Nc3ccnn3CC3CC3)n2c1 +Cn1ncc2c1CCCN(C(=O)Cc1cccc(F)c1)C2 +CC(=O)Nc1ccc(C(=O)Nc2cccc(-c3cc[nH]n3)c2)cc1 +CNC(=O)CCNC(=O)Nc1ccc(Oc2ccccc2OC)cc1 +Cn1c(CN2CCN(c3cnccn3)CC2)nc2cc(Cl)ccc21 +COC(=O)c1ccccc1S(=O)(=O)NCCc1nc(C)cs1 +COc1ccc2[nH]c(=O)c(CNCCc3ccccc3C)cc2c1 +Cc1nnc(SCC(=O)OCc2ccccc2)s1 +N#CCCNS(=O)(=O)c1ccc(OC2CCCC2)cc1 +COc1cc(C)ccc1OCCC(=O)NC(C)C1CC1 +CC(C(=O)Nc1ccccn1)n1nc(-n2cccn2)ccc1=O +CC(=O)c1ccccc1NC(=O)COC(=O)c1cc2ccccc2[nH]1 +O=C(c1ccncc1)N(Cc1ccsc1)Cc1ccco1 +O=C(CCCn1cccc1)N1CCc2cc(F)ccc2C1 +CCc1ccccc1OC(=O)c1cc2c([nH]c1=O)CCCC2=O +Cc1cc(C)n2nc(C(=O)NCCCC3CCCC3)nc2n1 +COc1cc(C(C)NC(=O)NC(C)C)ccc1OCc1ccncc1 +C=C(C)Cn1c(=O)oc(=O)c2cc(C(C)=O)ccc21 +Cc1cc(C(=O)N2CCN(c3ncccn3)CC2)[nH]n1 +Cc1[nH]nc2c1NC(c1cccc(C#N)c1)NC2=O +O=C(c1cccc(F)c1)N1CCc2c(cnn2-c2ccccc2)C1 +NS(=O)(=O)c1ccc(NC(=O)Nc2cccc(F)c2)cc1 +Cc1ccccc1-n1cc(CO)c(-c2ccccc2)n1 +COc1ccc(NC(=O)C2CCCN(C(N)=O)C2)c2cccnc12 +COC(=O)CN(C(=O)Cc1cccc(F)c1F)C1CCOCC1 +Cc1ccc(C(=O)N2CC(C)C3(CCNC3=O)C2)cc1C +CCC(NC(=O)CCNc1ccccc1)c1ccc(C)cc1 +CCCOc1cccc(NC(=O)N2CCCC(C(=O)NCC)C2)c1 +CCN(Cc1ccco1)C(=O)CC(NC(C)=O)c1cccs1 +NC(=O)CSc1n[nH]c(=O)n1CCc1ccccc1 +COc1cc(C)ccc1Oc1ccc(NC(=O)C2COCCO2)cn1 +COc1cccc(C(=O)N(Cc2ccsc2)C2CC2)c1OC +Cc1cnc(-c2cccc(NC(=O)c3[nH]nc(C4CC4)c3Cl)c2)o1 +CCCC(=O)NCC1CCCN(C(=O)c2cnc3ccccc3n2)C1 +CCn1c(C)cc(C(=O)NCCc2ccccc2)c1C +Nc1c(Nc2cccc(C(F)(F)F)c2)ncnc1N1CCOCC1 +CCNC(=O)NCC#CCOc1cccc2c1OC(C)(C)C2 +O=C(NCc1ccccc1Cn1cncn1)C1CC(=O)N(C2CC2)C1 +O=C(CNC(=O)c1csc2c1CCCO2)Nc1ccc(F)cc1 +Nc1nc(CSc2nncs2)nc2ccccc12 +O=C(CC1CCCC1)Nc1ccc(C(=O)N2CCOCC2)cc1 +Cc1cccc(-n2ccnc2SCC(=O)NC(C)C)c1 +Fc1cc(F)c2c(c1F)C(c1ccncc1)NCC2 +CC(C)c1cc(C(=O)NCc2cn3c(n2)SCC3)nc2ncnn12 +CCC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1 +Cc1c(CN2Cc3ncccc3C2=O)oc2ccccc12 +CCn1nc(C)c2nnn(CC(=O)NC)c(=O)c21 +COCC(C)(O)CNC(=O)Nc1ccccc1C(F)(F)F +O=C(NCC#CCOc1cccc2ccccc12)c1ccc[nH]c1=O +CN(CCOc1ccc(F)cc1)C(=O)CC1C=CCC1 +OC(COC1CCC1)c1cccc(C(F)(F)F)c1 +CC(C)c1nc(CNc2ncnc3[nH]cnc23)no1 +CC(=O)N1CCCC(c2cnc(-n3ccnc3)cn2)C1 +CCN(CCc1nccs1)C(=O)Nc1ccc(C(C)=O)c(C)c1 +CCS(=O)(=O)NC(C)c1ccc(OC)c(F)c1 +CC(=O)c1ccc(Cl)c(C(=O)NC2CCCC2)c1 +O=C(Nc1nc2cc3c(cc2s1)OCCO3)C1CC2CCC1O2 +N#Cc1ccc(-c2ccc(N3CCOCC3)s2)cc1 +CCOCC1CCCN(C(=O)c2cccnc2OCC(C)C)C1 +CCNC(=O)Cn1c(=O)c2c(ncn2CC(C)C)n(CC(C)C)c1=O +C#Cc1cccc(NC(=O)CCc2c(C)nc3nc(N)nn3c2C)c1 +Cn1nnc2c(SCc3ccccc3)ncnc21 +COc1ccnc(NC(=O)c2cc3cc(Cl)ccc3[nH]2)c1 +Cc1ccc(Cn2nccc2NC(=O)NCCc2ccccn2)s1 +COc1ccc(CNC(=O)c2ccc(F)cc2F)cc1 +CN(C)C(=O)N1CCN(C(=O)C2CCC(=O)N2)CC1 +CC(C)(C)OC(=O)CCN1CCN(c2ccccc2)CC1 +CCC(C#N)Oc1cccc(CNC(=O)c2ccc(F)nc2)c1 +CCN(C)C(=O)c1cccc(C(=O)OC2CCCC2OC)c1 +CC1Cc2ccccc2C1NC(=O)CNC(=O)NCc1ccco1 +CNC(=O)c1cnn(-c2ccccc2C)c1C1CC1 +Cc1ncc(-c2ccncc2)c(CCNC(=O)C2CC=CCC2)n1 +CC1CCN(c2ccc(=O)n(CC(=O)Nc3ccccn3)n2)CC1 +CCOCC1CN(C(=O)C2CCOCC2)Cc2cnn(C)c21 +COc1ccc(OC(C)C)c(NCc2noc(C(C)C)n2)c1 +O=C(NCC1(O)CCc2ccccc2C1)c1cc(C2CC2)on1 +O=C(N1CCOCC1)N1CCCC1c1nc(-c2ccccn2)no1 +O=C(CSc1nnc(-c2ccc(O)cc2)o1)Nc1ncccn1 +Cc1ccc(OCC(=O)N2CCN(C(=O)C3CCCO3)CC2)c(C)c1 +CC(=O)Nc1cc(C(=O)N(C)CCOc2ccc(F)cc2)ccc1C +Cn1nc(-c2cccc(Br)c2)nc1C1CC1 +COc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1N +CC(c1ccncc1)N(C)C(=O)Cc1c[nH]c2cc(F)ccc12 +N#Cc1cccc(-n2nnc(-c3ccco3)c2N)c1 +CCCc1cc(C(=O)NC(C)c2ccccn2)sc1C +COc1ccc(OCC(O)CN2c3ccccc3CC2C)cc1 +Cc1ccc2nc(COC(=O)CSc3ccncc3)cc(=O)n2c1 +O=C(NCc1ccc(O)c(F)c1)c1cnc(C2CCCO2)s1 +CC(C)(C#N)C(=O)NCCn1cnc2ccccc21 +Cc1nn(C)cc1C(=O)N(Cc1ccccc1)C(CO)C1CC1 +COc1cccc2c1OCCC2NCCc1ccc(F)cc1 +Cn1ccc(C(=O)NCc2cn(-c3ccccc3)nn2)cc1=O +CCOCc1ccc(NC(=O)NCC(C)(C)c2ccncc2)cc1 +O=C(CCCc1cccs1)NCC1CN2CCCCC2CO1 +NC(=O)c1ccc(NC(=O)CCCc2nc3ccccc3s2)cc1 +CC(C)CC(=O)N1CCCN(C(=O)c2ccccc2Cl)CC1 +Cc1cccc(C)c1NC(=O)COc1cccc(Br)c1 +COC(=O)c1cc2occc2n1Cc1ccc(C)cc1 +Cc1ccc(OCC(=O)n2nc(C)c(Cl)c2C)cc1 +Cc1nnc(SCC(=O)c2ccc3c(c2)NC(=O)CO3)n(N)c1=O +CCCn1nc(C(=O)N(C2CCCC2)C2CCCC2)ccc1=O +CCOc1ccc(F)c(C(=O)Nc2ccc3c(c2)OCCO3)c1F +CC(=O)NC(C)(C)c1noc(-c2cc(C3CC3)n(C(C)(C)C)n2)n1 +Cc1cnc(C(=O)Nc2onc3c2CCCC3)cn1 +CCOc1ccc(NC(=O)c2cc(S(N)(=O)=O)oc2C)cc1 +O=C(OCC(=O)N1CCCC1)c1cc2c(s1)-c1ccccc1CC2 +COc1ccc(C(C)C)cc1S(=O)(=O)NC1CCCNC1=O +Cc1c(NC(=O)N2CCC(CO)CC2)cccc1OCC(F)(F)F +Nc1ccc2c(c1)N(CC(=O)NCC1CC1)CCS2 +CC(=O)c1ccc(OCCOc2ccc3c(c2)OCO3)cc1 +Cc1nnc2c(=O)n(CC(=O)NCc3ccccn3)c3cccnc3n12 +CCOC(=O)C(CC)n1nnc(C(C)=O)c1-c1ccccc1 +CCOc1ccc(Cl)c(C(=O)N2CCNC(=O)C2)n1 +Oc1cccc(CC2NCCc3cc(Cl)c(O)cc32)c1 +CCOC(=O)c1cnn(-c2cc(OC)ncn2)c1C +CCNc1ncc(S(=O)(=O)N(C)CC(C)O)cn1 +CC(=O)NC(C)(C)c1noc(-c2c(Cl)c3ccccc3n2C)n1 +O=C(NCc1cccs1)C1CN(C(=O)c2cccs2)C1 +CCN(CCOC(C)C)Cc1nc2ccccc2c(=O)[nH]1 +NC(=O)COC(=O)c1cnn(-c2ccc(Br)cc2)c1 +Cc1cc(COC(=O)c2cc(S(=O)(=O)N(C)C)ccc2F)no1 +CCOc1ccc(C(=O)Nc2ncccc2C)cc1OCC +O=C(CCc1nccs1)c1ccc2c(c1)OCCCO2 +COc1cc(N(C)Cc2cc(C(C)(C)C)n[nH]2)ncn1 +CCCCn1ncnc1-c1cnc(NC(C)C)nc1 +CCCn1ccnc1SC(C)C(=O)Nc1ccc(C)cc1 +O=C(OCCn1c(=O)oc2ccccc21)c1cc(F)ccc1F +CC1CCN(c2ncnc(N3CCCCC3C)c2N)CC1 +Cc1cccc(CNc2ccc(C(=O)N3CCC(CO)CC3)cc2)c1 +CC(C)N(CC(F)(F)F)C(=O)c1ccc2c(c1)NC(=O)CS2 +COc1ccccc1-c1nc2ccc(CO)cc2o1 +O=C(COC(=O)C1COc2ccccc2O1)Nc1cccc(Cl)c1 +COc1ccccc1CN(C)C(=O)CSc1n[nH]c(N)n1 +Cn1nc(C(=O)NCC(=O)Nc2cccc(F)c2)ccc1=O +c1cnc(N2CCCC(Nc3nc4ccccc4s3)C2)nc1 +O=C(NCC1Cc2cc(F)cc(F)c2O1)c1ccccc1F +CCC(C)C(NC(=O)c1cccc(NC(C)=O)c1)C(N)=O +COc1cc(CC(=O)N(CCC(N)=O)c2ccccc2)ccc1C +CC(C)CCC(=O)N1CCC(OCc2ccc(F)cc2)CC1 +O=C(Cn1cncn1)NC(Cc1ccccc1Cl)c1ccccc1 +O=C(c1ccccc1Cl)N1CCN(c2ccc(F)cc2)CC1 +O=C(NC1CC(=O)N(C2CC2)C1)c1scnc1C1CC1 +CC(=O)c1ccc2c(c1)N(Cc1ccccc1Cl)C(=O)C(C)O2 +CNC(=O)c1ccnc(S(N)(=O)=O)c1OC1CC1 +CS(=O)(=NC(=O)c1ccc2nnsc2c1)c1ccccc1 +COCC(=O)N1CCCC(OCc2cccc(OC)c2)C1 +O=C(c1ccco1)N1CCOC2(CCN(Cc3nccs3)CC2)C1 +Cc1nccn1-c1cncc(N2CCC(c3ccnn3C)CC2)n1 +O=C(Nc1nnc(Cc2cccs2)o1)c1cccc(F)c1 +Cc1cccc2nc(COc3ccccc3Cl)cc(=O)n12 +O=C(NCCNC(=O)c1cccnc1)NCC1CCCO1 +COc1ccc2c(c1)OCC(C(=O)NCC(C)(C)c1ccncc1)C2 +COc1cccc(CCC2CCCN(C(=O)c3ocnc3C)C2)c1 +O=C(c1cnccn1)N1CCN(Cc2c(F)cccc2Cl)CC1 +COC(=O)C1CCCCN1C(=O)CCCSc1ccccc1 +CNC(=O)c1cccc(NC(=O)NCCCC2CCCC2)c1C +CC(=O)NCC1CCCN(C(=O)c2csc(-c3cccs3)n2)C1 +CCn1ccc(C(=O)N2CCCC(C)(C(=O)NC)C2)n1 +CCc1noc(CNc2ccccc2C(=O)NCC(C)C)n1 +Cc1cc(NC(=O)CCc2ccccc2Br)no1 +COc1cccc(NC(=O)C2CC(=O)N(C(C)c3ccccc3)C2)c1 +CCCCCNC(=O)C1CCN(C(=O)C2CC3CCC2O3)CC1 +CCC1CN(C(=O)NC(CC)c2cc(F)ccc2F)CC(C)O1 +Cc1cccnc1CNC(=O)c1cnn(-c2ccncc2)c1C +CC(Oc1ccccc1C#N)C(=O)N1CCCCC1Cn1cccn1 +Cc1cncc(Oc2ccc(Br)cc2)n1 +Cc1csc(C(C)NC(=O)Nc2cc(Cl)ccc2F)n1 +CC(C)C(=O)N1CCc2nc(-c3ccccc3)oc2C1 +COc1ccc(NC(=O)CCOC2CCCCC2)c(N)c1 +C#CCNC(=O)CNC(=O)Nc1cc(Cl)ccc1C +O=C(NCCNC(=O)c1cccnc1)Nc1ccc(Cl)c(F)c1 +CN(Cc1nc2ccccc2s1)C(=O)Cc1ccc(F)c(F)c1 +CCC(C)C(=O)Nc1cccc(CNC(=O)C2(C#N)CCCC2)c1 +CC(C)NC(=O)CN(C)C(=O)c1cc(Cl)c2c(c1)OCCO2 +COc1ccc(CNC(=O)c2cccc3ncccc23)cn1 +COc1cc2nc(C(C)O)n(C3CC3)c2cc1OC +CCOc1ccc(OC)c(-c2ccc(C(N)=O)c(N)n2)c1 +Cc1cc(NC(=O)C2CC3CCC2C3)ccc1S(C)(=O)=O +Cc1ccc(C)c(OC(C)C(=O)Nc2ccccc2C(N)=O)c1 +COc1cccc(C(=O)N(C)Cc2ccccc2Cl)c1OC +O=S(=O)(Nc1ccn(Cc2ccccc2)n1)c1cc(F)ccc1F +COc1ccc(NC(=O)c2ccc(C)nc2N)cc1Cl +Cc1ccc(N)cc1NC(=O)COc1cccc(Br)c1 +O=C(c1cn(Cc2ccccc2)nn1)N1CCOC2CCCC21 +CCCC(=O)c1ccc2c(c1)N(CC(=O)NCC(C)C)C(=O)C(C)O2 +CN(Cc1ccccn1)C(=O)NCc1cn2cc(Cl)ccc2n1 +Cc1ccccc1-c1nn(-c2ccccc2)cc1C(=O)N1CCCC1 +CCC1CN(C)c2ccccc2CN1C(=O)CCOCC1CCCO1 +CCn1ccc(-c2cc(=O)n3ncc(-c4ccc(F)cc4)c3[nH]2)n1 +N#Cc1ccccc1Cn1nnc(-c2ccsc2)n1 +CC(C)CC(=O)Nc1ccc(NC(=O)C2CCC2)cc1 +Cc1noc(C)c1CN(C)C(=O)c1cccc(CCC(C)(C)O)c1 +CC(C)(C)CC(=O)N1CCCC1C(=O)N1CCc2cc(F)ccc2C1 +COc1ccc2c(ccn2CC(=O)NCCc2ccccn2)c1 +Cn1nc(-c2ccccn2)nc1CCCn1cncn1 +CCn1cc(CN2CCOC(c3ccccc3Cl)C2)cn1 +CCn1cc(C(=O)Nc2ccc(Br)cc2F)cn1 +CC(C(=O)N1CCN(c2cc(C#N)ccn2)CC1)n1cncn1 +N#Cc1ccccc1NC(=O)Nc1ccccc1F +COc1ccc(C(=O)N(C)Cc2ccc(F)cc2F)cc1OC +O=C(Nc1cccc(OC2CCCC2)c1)c1cc2n(n1)CCCO2 +COCCOc1ccc(NC(=O)C2CCOCC2)cn1 +CCC(CC)NC(=O)C(C)NC(C)c1ccc2c(c1)OCCO2 +COC(=O)c1ccc(-c2ccccc2)n2nc(C)nc12 +CS(=O)(=O)c1ccc2nc(NCCc3cccs3)sc2c1 +COc1ccc(N(C)C(=O)CC2OCCc3ccsc32)cc1OC +Cc1cc(Br)ccc1NS(=O)(=O)c1c[nH]nc1N +CC1c2ccsc2CCN1C(=O)Cc1cccc(F)c1 +Cc1cc(C)c2oc(NC(=O)c3ccnc(-n4cncn4)c3)nc2c1 +CCCCSc1nnc(-c2cn(C)nc2OC)n1C +Cc1nc(N2CCCCC2)ncc1C(=O)Nc1ccc(F)cc1 +CC1CCCC(NC(=O)CSc2nc(N)cc(N)n2)C1C +O=C(Nc1ccc2c(c1)OC(F)(F)O2)C1CCC1 +CCCN(Cc1ccccc1)C(=O)Nc1nnc(C2CC2)s1 +CCOC1CCCN(C(=O)NCc2ccnc(OC3CCCC3)c2)C1 +O=C(Nc1ccc2c(c1)OCCO2)c1cc(F)ccc1-n1cnnn1 +Cc1cc(NC(=O)c2sc(-c3cccs3)nc2C)ccn1 +CCOc1ccc(F)c(C(=O)N2CCC(C(N)=O)C2)c1F +C=CCN(Cc1cccc(C#N)c1)C(=O)Nc1ccccn1 +Cc1nccc(N2CCCC(C)(c3[nH]ncc3S(C)(=O)=O)C2)n1 +Nc1ccc2oc(=O)n(CCOc3ccc(F)c(F)c3)c2c1 +Cc1[nH]ncc1-c1nn2c(-c3ccco3)nnc2s1 +COc1cc(-c2noc(-c3cccc(OCC(N)=O)c3)n2)ccn1 +O=C(CCCOc1ccccc1F)Nc1cccc(-c2ccn[nH]2)c1 +CCC(=O)N1CCCCC1C(=O)Nc1cc(C2CCCC2)[nH]n1 +Cc1nc2cc(N)ccc2n1CCc1ccccc1 +COc1ccc(-n2[nH]c(C(F)(F)F)cc2=O)cc1 +Cc1ccc(C)c(NC(=O)COc2ccc(C(N)=O)cc2)c1 +Cc1ccc(NC(=O)c2cc(C)oc2C)c(OCC(=O)N(C)C)c1 +CCc1nc2nc3c(cn2n1)C(=O)CC(c1cccc(C)c1)C3 +COc1ccc(C(=O)NCc2ccc(NC(N)=O)cc2)cc1 +Cc1cccc(-c2csc3c(=O)n(C)cnc23)c1 +Cn1c(=O)c(C=Cc2ccsc2)nc2ccccc21 +CN(CCO)C(=O)c1ccc(-c2nn(C)c(=O)c3ccccc23)cc1 +Cc1noc(CCCC(=O)N(C)Cc2ccc(C)o2)n1 +O=C(COc1ccc(F)c(F)c1)Nc1ccc2c(c1)OCO2 +CCc1n[nH]c(NC(=O)Cc2cccc(F)c2F)n1 +CN(Cc1ccccn1)C(=O)Nc1cccc(Cl)c1-n1cccn1 +COc1csc(C(=O)N(C2CC2)C(C)c2ccccn2)c1 +COC(=O)CCC(=O)c1ccc(-c2ccccc2)cc1 +COc1ccc(C2(CNC(=O)c3ccccc3)CCOCC2)cc1 +CCC1CCC(C(=O)NCc2nc(Cc3ccccc3)n[nH]2)CC1 +O=S(=O)(NCCc1cccnc1)c1ccc(C(F)(F)F)nc1 +O=C(NC12CC3CC(CC(C3)C1)C2)C1CC(=O)N(C2CCOCC2)C1 +COc1cccc(C(=O)N2CC(=O)Nc3ccccc32)c1F +COC(=O)c1sccc1CNC1(C(=O)OC)CCC(C)CC1 +Cc1ccc(NC(=O)COC(=O)c2ccccc2C)cc1 +Cc1sc2nc(SC3CC(C)OC3=O)n(C)c(=O)c2c1C +CC(C)Oc1ccc(CNC(=O)c2cccc(C#N)c2)cn1 +C=CCN(c1ccc(C(=O)OCC)cc1)S(C)(=O)=O +O=C(Nc1ccon1)c1ccccc1Br +CCCCC(=O)Nc1cc(NC(C)=O)c(OC)cc1OC +CCOCCCC(=O)Nc1cnn(-c2ccccc2F)c1 +N#CC1CCN(CCOc2cccc(Cl)c2)CC1 +Cc1c(C(=O)NCC2(Sc3ccccc3)CC2)cnn1C +CNC(=O)NC(C)(C)C(=O)Nc1ccc(F)c(Cl)c1 +CCCn1nc(C(=O)Oc2ccc(C)cc2OC)ccc1=O +Cc1ccccc1C(=O)NC(C)C(O)c1ccccc1 +Cc1cn2cc(CNC(=O)c3ccc(C#CC(C)(C)O)o3)nc2s1 +CC(=O)Nc1ccc2c(c1)N(Cc1c(C)noc1C)C(=O)CO2 +CC(=O)Nc1ccc(O)c(C(=O)Nc2ccnc(C)c2)c1 +CC(C)Cc1nc2cnccn2c1NCc1ccc2c(c1)OCO2 +CN(CC(=O)Nc1ccc(F)c(-n2cccc2)c1)S(C)(=O)=O +CCC(C)n1ncc(S(=O)(=O)NCc2ccco2)c1N +CCSc1nc2n(n1)C(c1ccc(O)cc1)C(C(=O)OC)=C(C)N2 +CC1=C(C(=O)OC(C)C)C(c2ccco2)NC(=O)N1C +CCn1c(SCC(O)CO)nnc1-c1ccccc1OC +CCc1nncn1CCNC(=O)Nc1cc(F)c(OC)c(F)c1 +CCc1nc(CC(=O)N=c2sccn2C)cs1 +COC(=O)Nc1cc(NC(=O)NCc2cnn(C)c2C)ccc1F +COCC(=O)Nc1cccc(C(=O)Nc2ccc(OC)cc2)c1 +CCn1cc2c(n1)C(COCC1CC1)CN(Cc1cccnc1)C2 +NC(=O)COC(=O)c1csc(NCc2ccccc2)n1 +Cc1nc2nc(SCC(F)(F)F)nn2c(C)c1C +NC(=O)c1cc(NC(=O)NC2(c3ccc(F)cc3)CCC2)ccc1F +CCc1noc(CC)c1CC(=O)Nc1ccc(OC)c(OC)c1 +Cc1cccc(C)c1NC(=O)C(C(F)(F)F)C(F)(F)F +CC(C)CCn1ccc(NC(=O)N2CCOCC2C2CC2)n1 +COCc1nc2ncc3c(=O)n(CCO)ccc3n2n1 +O=C(NCCc1cn2ccsc2n1)c1cn(-c2ccccc2)nn1 +CCN(CC)C(=O)CN1CCc2nc(NC(=O)C3CC3)sc2C1 +Cc1c(CNC(=O)c2cccnc2OCC(F)F)cnn1C +Cn1nc(-c2cccnc2)c2[nH]c(-c3cnn(-c4ccccc4)c3)nc21 +CC1COCCN1S(=O)(=O)c1ccc(Cl)c(N)c1 +COC(=O)c1c(C)cccc1NS(=O)(=O)c1cc(C)ccc1OC +FC(F)(F)COCc1ccc(CNc2ccc3nnnn3n2)cc1 +Cc1cc(C)n(CC(=O)NCc2ccc(Cl)cc2)c(=O)c1C#N +CCOCCSc1nc(-c2cc(Cl)ccc2OC)n[nH]1 +O=C(CCCS(=O)(=O)c1ccc(F)cc1)Nc1ccc(F)cc1 +CCCCNC(=O)C(C)S(=O)c1nnc(-c2ccc(C)cc2)n1C +CCc1ccc(C(=O)N(C)Cc2cc(OC)c(OC)cc2SC)o1 +COc1cccc(CC(=O)NCCCC(N)=O)c1 +Cc1ccc(C(C)NC(=O)N(C)CC2CCOCC2)s1 +O=C(CNCc1ccccn1)NCCc1ccccc1 +O=c1ccc(-c2noc(Cc3cccc(C(F)(F)F)c3)n2)c[nH]1 +Cc1ccn2c(-c3cccc(Cl)c3)nnc2c1N +Cc1ccc(C(CNC(=O)c2c(F)cccc2F)OCCO)cc1 +CCn1cc(CC(=O)Nc2nc3ccc(F)cn3n2)c2ccccc21 +CNc1nc(-c2ccc(CNC(C)=O)s2)c(C)s1 +Cc1cc(C)n(C2CN(c3nnc(C4CC4)o3)C2)n1 +Cc1cc(C(=O)N(C)Cc2nc(-c3cccnc3)no2)c(C)o1 +COC(=O)CC1C(=O)NCCN1Cc1csc(C(C)(C)C)n1 +CCn1nc(-c2ccc(F)c(F)c2)cc(C#N)c1=O +CCn1c(=O)c2nscc2n(CC(=O)NCc2ccccc2)c1=O +COc1cccc2c1OCC(CNC(=O)CN1CCOCC1)C2 +O=C(COCC(F)(F)F)NCc1cn(-c2ccccc2)nn1 +CN(C)C(=O)C(Sc1nnnn1C)c1ccccc1 +CCn1cnnc1CNC(=O)CCSc1ccccc1Cl +Cc1ccc(C(=O)NC2CCCc3[nH]c(=O)c(C(N)=O)cc32)c(C)c1 +CSc1ccc(C)c(C(=O)NCCNC(=O)c2ccccc2O)c1 +O=C(c1cccs1)N1CCCC1c1nnc2n1CCCCC2 +O=C(NCCCSc1ccccc1)c1cccnc1 +Nc1cc(Oc2ccc(Br)cc2)nc(N)n1 +COC(=O)c1cccc(NS(=O)(=O)c2ccccc2F)c1 +N#Cc1ccc(CNC(=O)c2ccc(-c3cscn3)cc2)cc1 +Nc1cc(=O)[nH]c(=O)n1CCc1c[nH]c2ccccc12 +CC1CC1C(=O)N1CCC(NC(=O)c2ccsc2)CC1 +O=C(Nc1ccccc1)C1CCN(C(=O)c2ccco2)CC1 +CC(C)CN(CC(F)(F)F)S(=O)(=O)c1ccc(C#N)cc1 +CCn1nnnc1COc1cccc(C(=O)Nc2cc(C)ccn2)c1 +CCOc1ccc(CC(=O)N2C(C)COCC2C)cc1 +CC(=O)Nc1ncc(S(=O)(=O)Nc2ccccc2F)s1 +O=c1sc2ccccc2n1S(=O)(=O)c1ccccc1 +COc1cc(N)ccc1C(=O)Nc1c(C)cc(C)cc1C +COC(=O)c1nc2ccccc2n1Cc1ccc(C)cc1 +Cc1nc(CCNc2ccc(C(F)(F)F)cc2)n[nH]1 +Cc1ccc(NC(=O)CCc2ccc3nc[nH]c3c2)cc1F +CC(=O)NCC(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +O=C(NCCN1CCc2ccccc21)c1c[nH]nc1-c1ccccc1 +Cc1cc(S(=O)(=O)NCCC(O)c2ccco2)ccc1F +Nc1cc(F)c(F)cc1NC(=O)Cc1ccc(Cl)cc1 +COCCNC(=O)CSc1nnc(-c2ccncc2)o1 +CC1CCN(C(=O)C2CC(C)Nc3ccccc32)CC1 +COc1ccc(C(=O)NCc2ccc(Cn3cncn3)cc2)cc1 +Cc1ccccc1C1(O)CCN(Cc2cccs2)C1 +Cc1nc(N(C)C)ncc1C(=O)NCCCn1nccc1C1CC1 +CCOC(=O)C1CCCN(C(=O)c2ccc(F)c(F)c2)C1 +CN(CCO)C(=O)Nc1ccc(Oc2ccc(C#N)cc2)cc1 +CCOc1cc(C2NCc3ccccc3-n3cccc32)ccc1O +Cc1nc(COc2cccc3c2CCC3=O)cs1 +COC(=O)C(C)CNC(=O)Nc1ccc(F)cc1C(F)(F)F +CNC(=O)c1ccc(S(=O)(=O)NC(C(=O)OC)C(C)(C)C)cc1 +COC(=O)c1ccc(OC(C(=O)NC2CC2)c2ccccc2)cc1 +Cc1nc(C2CN(S(C)(=O)=O)CCO2)cc(N2CCCCC2)n1 +N#CCCCOc1cccc(NC(=O)c2cccc3[nH]ccc23)c1 +CCn1ccnc1CN1CCCN(C(=O)Cc2csc(C)n2)CC1 +CCOc1cc(N2CCCC2c2nnc3n2CCCCC3)ncn1 +CCCOC1CCCN(C(=O)Cc2cccc(OCC#N)c2)CC1 +O=C(Nc1ccccc1Cl)c1ccccc1-n1cnnn1 +CC(=O)c1ccccc1NC(=O)CCC1CCCO1 +CCOc1ccc(-c2cn(C(C)C(=O)NC)nn2)cc1CO +CN(Cc1ccco1)C(=O)NCC1(c2ccccc2F)CC1 +Cc1ccc(C(=O)CCC(=O)Nc2cc[nH]n2)s1 +CCCC(=O)Nc1cccc(C(=O)NC(C)CCC)c1 +N#CC(c1ccco1)N1CCN(C(C#N)c2ccco2)CC1 +O=c1[nH]nc(CSc2ncnc3sc4c(c23)CCC4)[nH]1 +O=C(Nc1nnc(-c2cccs2)s1)c1ccc2c(c1)OCO2 +Cc1cccc(-c2noc(C(=O)NCc3ccc(F)cc3)n2)c1 +COc1ccc2c(c1)OCC(C(=O)N1CCOCC1CC(C)C)C2 +COc1cc(C(=O)Nc2nc3c(s2)C(=O)CCC3)ccc1Cl +Cc1noc2ncnc(NC(CCn3cncn3)c3ccccc3)c12 +CC(C(=O)N1CCN(Cc2ccccn2)CC1)n1cncn1 +Nc1cc(N2CCCC(CO)(CCOc3ccccc3)C2)ncn1 +O=C(COc1ccccc1)NCCn1cnc(-c2ccccc2)cc1=O +CCCn1nc(CO)cc1-c1ccc(NC(C)=O)cc1 +Cc1ccc(CC(=O)Nc2cccc(OCC#N)c2)s1 +COc1ccccc1OCCCC(=O)NC(C)C +CN(C(=O)CCN1C(=O)COc2ccccc21)C1CCCCC1 +Cc1nnc(-c2ccc(S(=O)(=O)NCc3cccs3)s2)o1 +CCCOCC(=O)Nc1ccc(NC(N)=O)cc1 +Cc1ccc(NC(=O)COc2nnc3ccccn23)cc1C +CCC1CCCN(C(=O)Nc2ccc(NC(=O)OC)cc2)C1 +CCOc1cc(CNc2ccc(F)cc2C)ccc1O +Cc1nc(CCNC(=O)Nc2ccc(F)nc2)nc2c1CCC2 +COCC1CCCN1Cc1nc(N)nc(N(C)C)n1 +CCNc1snnc1COc1ccc2c(c1)OCO2 +OCc1nnn(CCCc2ccccc2)c1-c1ccco1 +Cc1ccc(NC(=O)NCc2cccc(OCC(=O)N(C)C)c2)cc1 +CCN(CCC(=O)N1CCN(C(C)=O)CC1)C(=O)c1cnccn1 +N#Cc1ccc(N2CC(NC(=O)C3CCOCC3)C(C3CC3)C2)nc1 +O=C(C1CCCc2ccccc21)N1CCCC(N2CCNC2=O)C1 +CC(C)COC(=O)N1CCN(C(C)C(=O)Nc2nccs2)CC1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NC(C)Cn1cccn1 +Cc1ccc(C(=O)Nc2cc(-c3cccs3)n[nH]2)s1 +CCC(CC)N(CCO)C(=O)c1ccc(N)cc1Cl +CC(NC(=O)Nc1ccccc1)C(=O)N(C)C(C)C1CC1 +CCOC(CC)C(=O)Nc1ccc(C(=O)N(C)C)cc1 +CCOc1ccc(S(=O)(=O)NCc2ccccc2)cc1C(N)=O +O=C1CCCN1c1cccc(-c2csc(Nc3ccccn3)n2)c1 +CC(NC(=O)NCc1cnn(C)c1)c1ccc(F)cc1 +COc1ccc(OC)c(CC(=O)Nc2cnc3c(c2)c(C)nn3C)c1 +Cc1nn(C)c(C)c1OS(=O)(=O)c1cccc2cnccc12 +CN(CC(=O)N1CCOc2ccc(F)cc21)C(=O)c1cccs1 +CCOc1ccc(-n2ncc(C(=O)NC(C)(C)C)c2C)nn1 +O=c1cc(CNc2cccc(F)c2F)nc2sccn12 +Cc1ccc(S(=O)(=O)NCC(C)(O)c2cccs2)cc1 +COCC(C)NC(=O)c1cnc(Cc2ccccc2)s1 +CCOC(CC)C(=O)Nc1ccc(Br)cc1O +Cc1cn(CC(=O)NCc2cccc(-c3nc[nH]n3)c2)c2ccccc12 +COc1ccc(CNC(=O)NC2CCCCC2)cc1 +O=C(NCCc1cccs1)c1coc(NC(=O)c2cccs2)n1 +Cc1cc(NC(=O)N(C)CCc2ccccn2)c2ncccc2c1 +CCc1ccc(C(C)NC(=O)c2cc(C)oc2C)cc1 +O=C(Nc1ccc2c(c1)OCO2)c1cccc(O)c1 +CCC(=O)c1ccc2c(c1)N(C(C)C(=O)OC(C)CC)C(=O)C(C)O2 +O=C(NCc1cccnc1)N1CCCC1c1cccc(Cl)c1 +Cc1noc(NCc2cnc(C)n2-c2ccccc2)n1 +Nc1ccc(NC(=O)c2cccc(O)c2)cc1C(F)(F)F +CCc1onc(C)c1NC(=O)CSc1ccc(F)c(F)c1 +CCC(C)C(NC(=O)COc1cc(Cl)cc(Cl)c1)C(N)=O +C=C(C)COc1ccc(C(C)=O)cc1NC(=O)C(C)C +CCN1C(=O)Cc2cc(NC(=O)CSc3ccc(F)cc3)ccc21 +COC(=O)NCc1ccc(NCc2noc(C(C)C)n2)cc1 +CN(Cc1cccc(-n2cccn2)c1)C(=O)CCCn1cncn1 +CC(=O)c1ccc(NS(C)(=O)=O)c(Oc2ccc(F)cc2F)c1 +CCCC(=O)N1CCC(C(=O)Nc2cc(C(N)=O)ccc2C)CC1 +O=C(NCCO)c1nc(-c2cccc3[nH]ccc23)no1 +COc1cccc(SCC(=O)NC2CCCC(C)C2)c1 +CC(C)N1C(=O)C(O)(CC(=O)c2ccccc2)c2ccccc21 +Cc1cccc(C2(C(=O)OCc3cc(=O)n(C)c(=O)n3C)CC2)c1 +Cc1ccc(-c2cc(C(=O)NCc3ccccn3)c3ccccc3n2)o1 +CC(=O)c1ccccc1NC(=O)c1cc(=O)[nH]c2ccccc12 +Cc1cccnc1CN1CCN(C(=O)CSc2nnnn2C)CC1 +CN(C)S(=O)(=O)NCCC1CCCCN1C(=O)c1cc[nH]n1 +CCN(CCO)C(=O)CCc1ncc(-c2ccccc2)o1 +COc1cccc(CN2CCc3nc4ccccc4c(=O)n3CC2)c1 +CCC(NS(=O)(=O)c1ccc(C(N)=O)cc1)C(C)C +Cc1ccccc1C(=O)CCN1CCOC(C)(C)C1 +COCC(=O)N1CCC(CCOc2ccccc2)CC1 +COc1cc(CNC(=O)NC2CCCC(C)C2)ccn1 +NC(=O)Cn1cc(Nc2ccc(S(=O)(=O)C(F)(F)F)cc2)cn1 +Cc1nonc1NC(=O)c1cccnc1OCC(F)F +CCn1cc(C#N)c(=O)n(Cc2nc(-c3ccccc3)no2)c1=O +Cc1ccc(N2CCC(C(=O)NCCc3ccccc3F)C2=O)cc1 +Cc1c(CCC(=O)Nc2cccc(C(F)(F)F)n2)cnn1C +O=c1c(Cl)c(Cl)cnn1Cc1nccn1CC(F)(F)F +Cc1nc(-c2ccc(-n3nncc3-c3cccs3)cc2)cs1 +CC(C)NC(=O)Nc1ccc(C(=O)OCC(F)F)cc1 +O=C(Nc1cnc2n1CCCC2)c1cnn(Cc2ccccc2)c1 +CCCNS(=O)(=O)c1cccc(C(=O)NCc2ccccc2)c1 +COC(=O)CC1C(=O)NCCN1C(=O)c1cc2ccccc2[nH]1 +CCOC(=O)C(Cc1nnc2c(C)ccnn12)NC +COC(=O)c1cc(CN(C)C(=O)c2n[nH]c3ccc(C)cc23)oc1C +C=CCn1c2c(ccc1=O)CC(NCc1cccc(C#N)c1)CC2 +CC1CN(C(=O)NCc2ccccc2F)CC1(O)C1CC1 +O=C(COC(=O)c1ccccn1)Nc1ccc(Br)cc1 +CC(C)(O)CNC(=O)C1(c2ccc(F)cc2F)CCOCC1 +CCOc1ccc(C(=O)Nc2ccccc2C(=O)OC)cc1OC +CC(=O)Nc1ccc(C#CCNC(=O)c2snnc2C)cc1 +Cc1ccc(C(=O)NCCSc2ccccn2)cc1 +O=C(CCNC(=O)c1ccco1)Nc1ccc(-c2nccs2)cc1 +Clc1cc(CNc2ccc3c(c2)COC3)c2ncccc2c1 +O=C(c1cc2c(s1)CCCCC2)N1CCCC(N2CCNC2=O)C1 +O=C1CN(C(=O)c2cc(-c3ccccc3Cl)[nH]n2)CCN1 +CC(O)CN1CCN(C(=O)CC2C(=O)Nc3ccccc32)CC1 +Cc1ccc(CCNC(=O)NC2CCN(CC(F)(F)F)C2=O)cn1 +CC1CCCC(CNC(=O)Nc2ccc(C(N)=O)cc2)C1 +Cc1noc(C)c1COc1cc(Cl)ccc1C(N)=O +NC(=O)c1cc(-c2cccc(Cl)c2Cl)no1 +Cn1cc(C(=O)Nc2ccc(C3CCc4nncn4C3)cc2)ccc1=O +COc1ccc(SCC(=O)NC(C)c2cccs2)cc1 +CCCCNC(=O)CN1CCOc2ccc(N)cc21 +Cc1nc(SCCCO)c2c(C)c(C)sc2n1 +COCC(C)NC(=O)CC1CSc2nc(C(C)(C)C)cc(=O)n21 +COc1ccc(-c2nc3nccc(-c4cccnc4)n3n2)cc1 +Cc1cccc(C)c1NC(=O)c1cccc(C(=O)N(C)C)c1 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)OCC1CCCCC1 +Cc1nc(C2CCN2S(C)(=O)=O)cc(N2Cc3ccccc3C2)n1 +N#Cc1ccc(F)c(C2NCCc3cc(F)cc(F)c32)c1 +Cc1cccc(N(CC(=O)N2CCC(C)CC2)S(C)(=O)=O)c1C +Cc1cccc(OCCC(=O)NCC2CN3CCCCC3CO2)c1 +C#CCNC(=O)C1(S(=O)(=O)c2ccc(C)cc2)CCC1 +Cc1cccc(-c2ccc(C(=O)NCc3nnc(C)o3)c(=O)[nH]2)c1 +Cc1cc(C)cc(C(=O)NCC(=O)NCC2CC2C)c1 +NC(=O)C1CCCCN1C(=O)C1COc2ccc(F)cc2C1 +CC(=O)N1CCc2ccc(C(O)CC(C)C)cc2C1 +Cc1csc(NC(=O)NCCCOC(C)c2ccccc2)n1 +CC1CC(C)CN(C(=O)CN2CCOC(CNc3cccnn3)C2)C1 +CCC(=O)Nc1cccc(NC(=O)CNC(C)c2ccccc2)c1 +COCC(O)CN(C)C(=O)c1cc(N)c(F)cc1F +Cc1nc(-c2ccc3c(c2)CCN3C(=O)C2CC(=O)N(C)C2)cs1 +Cc1cc(C(=O)CSc2ccccn2)c(C)n1Cc1ccco1 +COCCc1nnc(NC(=O)Cc2ccccc2Cl)o1 +O=C(c1cc2c(F)cccc2[nH]1)N1CCc2cc(F)ccc2C1 +CCC(CC)C(=O)NCc1cn2cc(Br)ccc2n1 +CC1CCN(C(=O)c2csc(-c3ccco3)n2)C(C)C1 +CCCCC(=O)Nc1ccc(-c2nc(CC)no2)cc1 +Cn1cccc1C(=O)NCC(c1ccc(F)cc1)N1CCOCC1 +C=CCNC(=O)c1ccc(S(=O)(=O)Nc2ccc(OC)cc2)cc1 +CCc1nc(CC(=O)NCc2ccc(-n3ccnc3C)nc2)cs1 +Cc1ccn(CCCn2cnc(-c3ccccc3)c2-c2ccco2)n1 +O=c1c2nnc3ncnn3c2ccn1CCc1c[nH]c2ccc(F)cc12 +O=C(NCCc1cccc(O)c1)c1cncc(Br)c1 +COC(=O)CC(Cc1ccc(F)c(F)c1)C(=O)OC +CCOC(=O)CN(Cc1nc(C)cs1)C1CCCC1 +COc1nc2c(cc1C(=O)NC1CC(=O)Nc3ccccc31)CCC2 +CNc1nc(-c2ccccc2OC)c(C)cc1C#N +Cc1ccc(C2(C(=O)N(C)Cc3cccs3)CCOCC2)cc1 +Fc1ccc(C2(NCc3nccs3)CCCC2)c(F)c1 +O=C(NCCN1CCOCC1)C1CN(S(=O)(=O)C2CC2)C1 +CCCOC(=O)c1ccc(NC(=O)C2CCCN2C(=O)C2CC2)cc1 +CC(C(=O)Nc1cccc(Cl)c1)S(=O)(=O)c1nccs1 +CCCC(=O)N1CCN(Cc2nc(-c3cccs3)cs2)CC1 +Cc1ccc(CN(C)Cc2cccc3cccnc23)s1 +Cc1nc(C)c(CCC(=O)N2CCCC2c2cccc(F)c2)c(=O)[nH]1 +NC(=O)NCCCCC(=O)NCC1CC=CCC1 +CC(C)C(O)C1NCCc2ccc(Cl)c(F)c21 +Cc1ccc(Nc2ncccc2S(N)(=O)=O)cc1C +CCC(C)(C)NC(=O)Cn1cnc2ccccc2c1=O +O=C(NC1CCN(C(=O)c2ccoc2)CC1)c1ccc[nH]c1=O +Cc1cc(SC2CCOC2=O)nc2c(C)cccc12 +Cc1nc(-c2nc[nH]n2)sc1C(=O)Nc1cccc2c1ccn2C +CS(=O)(=O)N1CCC2OCCCC2(COCc2ccncc2)C1 +O=S(=O)(Cc1ccccc1)N1CCCC(CN2CCOCC2)C1 +CCNC(=O)C1(NC(=O)c2scnc2C)CCCCC1 +COCCn1nc(C(=O)NCc2cn[nH]c2)ccc1=O +CCNC(=O)CN(CC)S(=O)(=O)c1ccccc1-c1ccccc1 +Cc1nc(N2CCCCC2)ncc1C(=O)Nc1ccccc1 +COc1ccc(Nc2nccc(OC)c2C#N)cc1 +COc1cc(C(=O)N2CCCC(C)C2)cc(OC)c1OC +CCCn1nccc1NC(=O)CN1CCCC2(C1)OCCO2 +O=C(Nc1ccc(-c2cnco2)cc1)c1c[nH]c2cccc(F)c12 +Cc1cc(C)n(-c2ccc(CNC(=O)Nc3cnn(C)c3)cn2)n1 +N#CCCN(CCC#N)S(=O)(=O)c1cccs1 +O=c1[nH]ncc(NCc2ccccc2OCc2ccccc2)c1Cl +COC(=O)Nc1ccc(NC(=O)NCc2ccc(C)s2)cc1 +Cc1ccc(=O)n(CC(=O)NCc2ccccc2Cl)n1 +Cn1cccc1C1CCCN1C(=O)Nc1ccc(-n2cncn2)nc1 +COc1ccc(Cl)cc1NC(=O)c1ccc(C)c(NC(C)=O)c1 +COC(=O)c1ccc(OCc2cc(C)on2)c(Cl)c1 +COc1ccc(Nc2c(C)cnc3c2c(=O)n(C)c(=O)n3C)cc1 +N#Cc1csc(C2NC3(CCCC3)C(=O)N2CC2CC2)c1 +CC1=CCC2CN(C(=O)CCNC(=O)c3ccccc3F)CC2C1 +Cc1cc(C(=O)NCCc2cccs2)c2c(=O)[nH]n(C)c2n1 +COC(=O)Cc1csc(COc2ccc(F)c(F)c2)n1 +C=CCN(C(=O)c1ccc(F)c(NC(C)=O)c1)C1CCCC1 +CCc1ccc(-c2nc(C)c(C(=O)NCCC(=O)OC)s2)cc1 +CCOc1cccc(OCCN2CCc3c(cnc(C)c3C#N)C2)c1 +CCOC1CCN(C(=O)CCC2CCCO2)CC1 +CCn1ccc2ccc(NC(=O)C3CCN(C(=O)C(C)C)CC3)cc21 +COc1cc(Cl)ccc1OCCN1CCOCC1 +COc1ccc(OC)c(CC(=O)N2CCC(OC)CC2)c1 +CCN(CC)C(=O)N1CCCn2nc(CN3CCNC(=O)C3)cc2C1 +COc1ccc(C(CO)C2CCCC2)c(OC)c1 +Cc1ccc(C)c(OC2CCN(C(=O)c3csc(C)n3)CC2)c1 +Cc1nn(C(C)(C)C)c(C)c1C(=O)NCC(CO)Cc1ccccn1 +CN(Cc1nnc(-c2ccccc2)o1)C(=O)Nc1ccc(Cl)cc1 +CC(C)N(C)S(=O)(=O)N1CCC(Oc2ccccc2)CC1 +CC(NC(=O)c1ccon1)C(C)(C)c1ccccc1 +Cc1nc(NC(=O)c2cccc(N)c2C)sc1C +CSc1ccccc1NC(=O)NCCCc1c(C)noc1C +CC(CO)CN(Cc1ccccc1)C(=O)c1ccc(CO)cc1 +CCNC(=O)C(C)NC(=O)CCc1ccccc1F +COc1ccc(CNc2cn[nH]c(=O)c2Cl)c(OC)c1OC +CCCNS(=O)(=O)c1ccc(Cl)c(OCCC)c1 +COCC(C)NC(=O)Nc1cccc(-c2nc(C)c(C)o2)c1 +O=C(NCc1cccnc1)c1c(Cl)cccc1Cl +CC(=O)c1ccccc1NC(=O)c1ccc(OCC(F)F)nc1 +CN(Cc1ccccc1)C(=O)NCCNC(=O)C1CC1 +Cc1cccc(NC(=O)c2cc(C(N)=O)cs2)c1C +CC(=O)Nc1cccc(NC(=O)c2ccc(N)nn2)c1 +O=C(NCc1ccco1)C1CC12CCN(C(=O)N1CCCC1)C2 +Cc1ccc(C#CCCO)cc1NC(=O)C1CC1C +O=C(NCCc1nc2ccccc2[nH]1)C1(c2ccccc2)CCOCC1 +Cc1cc(C)n(CC(=O)NCCC(O)C(C)(C)C)n1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)NCc1ccco1 +COc1ccc(C#N)cc1-c1ccc2c(c1)OCCO2 +CCCSc1cc(=O)n(-c2ccc(F)cc2)nc1C(=O)OCC +CCCCCN(C(=O)Nc1cc(C)nn1C)C(C)C +CC(=O)c1ccc(C(=O)Nc2cccnc2-n2cccn2)s1 +Cc1noc(C)c1CC(=O)Nc1ccc(C(N)=O)cc1 +CC(OCC(F)(F)F)C(=O)NCc1cccnc1-n1cccn1 +CN(Cc1ccc(C#N)cc1)C(=O)Nc1ccccn1 +Cc1cc(C)c(-n2cc(C)c(C)c(C#N)c2=O)c(C)c1 +COc1cccc(OCc2c(C#N)nnn2CCCO)c1 +COCCn1nc(C)c(CNC(=O)c2cccn2C)c1C +Cc1cc(C)cc(NC(=O)CNC(=O)c2cc(F)cc(F)c2)c1 +COCc1cccc(C(=O)N2CCCC2c2ccc[nH]2)c1 +CCOc1c(Cl)cccc1NC(=O)CNC(=O)NC +CC(O)CN1CCN(CC(=O)N(C)Cc2cnn(C)c2)CC1 +O=C(NCCc1ccoc1)c1ccc(Cl)c(Cl)c1 +Cc1cccc(CNc2ncc(C(N)=O)cc2Cl)n1 +CC(Oc1ccccc1)C(=O)Nc1ccnn1C(C)C +CC(c1ccco1)N(C(=O)c1cc(-c2ccncc2)on1)C1CC1 +O=c1nc(CN(Cc2ccco2)C2CCCC2)[nH]c2ccccc12 +COc1ccccc1CNC(=O)NCCCn1ccc2ccccc21 +COc1ccccc1C1CCN(Cc2cnc3ccc(C#N)cn23)C1 +CC(C)CN1CC(C(=O)N2CCNC(=O)C2c2ccccc2)CC1=O +C=C1C2C3CC(C)C1(C)CCC2(C(=O)OC)C(=O)O3 +O=C1CCCN1c1cccc(NCc2ccco2)c1 +COC(=O)N(C)CC(=O)NCC(C)(C)c1ccccc1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)c(Cl)c2)c1C +COc1ccnc(NC(=O)CCc2ccc(C(F)(F)F)cc2)c1 +COCCCNC(=O)C1CCN(C(=O)Nc2cccc(F)c2)CC1 +Cc1csc(CCCNC(=O)N2CCOCC2CC(C)C)n1 +CCn1ccc(NC(=O)CCN2C(=O)C(C)(C)c3ccccc32)n1 +CCC(C)C(=O)NCCNC(=O)c1ccc(Cl)cc1 +Cc1c(NC(=O)c2n[nH]cc2Cl)c(=O)n(-c2ccccc2)n1C +CN(C(=O)c1cccc(N2CCNC2=O)c1)C(C1CC1)C1CC1 +Cn1c(=O)c2[nH]c(=O)c(-c3ccc(Cl)cc3)nc2n(C)c1=O +CN(C(=O)c1cnn(-c2ccccc2)n1)C1CCc2ccccc2C1 +CCC1CN(C(=O)Nc2cc(F)ccc2OC)CCN1CC(F)F +CCN(C(C)COC)S(=O)(=O)c1ccnc(NC)c1 +O=C(NCc1nc(-c2ccc3c(c2)OCO3)no1)c1ccccc1 +COc1ccc(C#CCNS(=O)(=O)c2c(F)cccc2F)cc1 +CCc1ncc(C(=O)N2CCCCC2CCc2cccs2)cn1 +COc1ccc(Nc2cc(-n3nc(C)cc3C)ncn2)cc1 +COc1ccc(Cl)cc1NC(=O)c1cc(F)ccc1-n1cnnn1 +Cc1cccc2c1N(C(=O)CCN1CCOC1=O)CCC2 +CC(=O)Nc1ccc(C(=O)NCc2ccc(Br)cc2)cc1 +Cc1ccccc1NC(=O)N1CCCC1c1nc(C2CC2)no1 +COc1ccc(CN2CCc3nnc(C(C)C)n3CC2)cc1C +COc1ccc2c(c1)CCCCN2C(=O)c1ccsc1 +NC(=O)C(NC(=O)c1c[nH]c2ccccc2c1=O)c1ccccc1 +Cc1cnc(-c2cccc(NC(=O)NC3CCCCC3CO)c2)o1 +Cc1cc(C(=O)N2CCCCC2C)ccc1NC(=O)CCNC(N)=O +O=C(Cn1cc(C(=O)N2CCCC2)cn1)Nc1ccc(Cl)cc1 +CC(C)C1C(=O)NCCN1Cc1cc(=O)n2cc(Cl)ccc2n1 +Cc1cc(C(N)=O)ccc1NCc1c(F)cccc1Cl +Cc1ccccc1CC(C)(C)NC(=O)NC(C)c1nncn1C +O=C(NCc1cccnc1OCC(F)(F)F)N1CCCC(O)C1 +CCCc1noc(-c2cc(-c3cccs3)n[nH]2)n1 +COc1ccc(OC)c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1 +O=C(CNc1ccccc1F)Nc1ccc(Cl)cn1 +Cc1ccc(C(C)Nc2cccc(NC(N)=O)c2)s1 +CCCC(C)C(=O)N(Cc1ccco1)CC(F)(F)F +Nn1c(SCc2csc(-c3ccccc3)n2)nnc1C1CC1 +Cc1c(C(C)NC(=O)CCO)cnn1-c1ccc(F)cc1F +Cc1ccc(Cn2cc(NC(=O)c3cc(C)oc3C)cn2)cc1 +O=C(C1CC1c1ccco1)N1CCCC1c1nnc2n1CCCCC2 +Cc1ccc(S(=O)(=O)CC(C)NC(=O)c2ccc(C)o2)cc1 +CC1CCCCN1C(=O)CN1CCCSc2ccccc21 +COC(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1 +CCCNC(=O)CNC(=O)N(C)Cc1c(C)noc1C +Cc1ccccc1-c1nc(-c2ccc3nnc(C)n3c2)no1 +CC(C)(C)c1cc(NC(=O)Cn2cnc3sccc3c2=O)on1 +Cc1nc(N2CCN(c3cccc(N)c3)CC2)sc1C +CN(C)C(=O)CCNC(=O)N(C)Cc1ccccc1OC(F)(F)F +CC1CC(=O)Nc2ccccc2N1C(=O)C1CCCO1 +C=CCNC(=O)c1ccc(NC(=O)C(C)CCC)cc1 +CCCn1ccc(C(=O)Nc2ccc(C)c(Cl)c2)n1 +COc1cccc2c(=O)n(CC(=O)NCc3ccccc3)ccc12 +Cc1cccc(C(C#N)N(C)S(=O)(=O)c2cccs2)c1 +CC(C)NC(=O)Cn1c(Cc2cccnc2)nc2ccccc21 +COc1ccc(CNC(=O)c2cccc(F)c2)cc1NC(C)=O +Cn1nc2n(c1=O)CCN(S(=O)(=O)c1cccc(F)c1F)C2 +COc1ncc(CNCc2cccs2)c(OC)n1 +CC1(c2[nH]ncc2S(C)(=O)=O)CCN(c2ncccn2)CC1 +CCOC(=O)N1CCN(CCC(=O)Nc2ccccc2Cl)CC1 +CC(C)CNC(=O)c1ccc(=O)n(Cc2cccc(F)c2)n1 +C=CCNC(=O)c1cn[nH]c1-c1cccc(Br)c1 +CCC(C)c1csc(NC(=O)N(C)CC(C)C(=O)NC)n1 +Cc1ccc(S(=O)(=O)NCc2cscn2)c(Cl)c1 +O=C(NCC(O)c1ccc2c(c1)CCCC2)c1ccc(F)cc1 +Cc1noc(C)c1CN(C)C(=O)NCC1CN2CCCCC2CO1 +Cc1cc(CCNC(=O)CN(C)S(C)(=O)=O)on1 +CCOC(=O)CN(C)C(=O)CCc1ccc(Br)cc1F +CCc1ccc(CC(=O)Nc2nnc(-c3sc(C)nc3C)o2)cc1 +COC(=O)c1n[nH]c2cc(S(C)(=O)=O)ccc12 +CC(=O)Nc1ccccc1CN(C)Cc1nc2ccccc2n1C +Cc1ccc(-c2cc(C(=O)NCC(C)(C)N3CCOCC3)n[nH]2)s1 +CCOc1ccccc1CCC(=O)NCc1cc(C)oc1C +COc1ccc(C#CCNC(=O)Nc2cccc(OC)c2OC)cc1 +COc1cc2c(cc1OC)CCN(C(=O)c1nccnc1N)CC2 +Cc1n[nH]c(C)c1NC(=O)COc1ccc(C(C)(C)C)cc1 +Cn1cc(CC(=O)NCc2ccoc2)c2ccccc21 +CCc1cc2c(=O)n(CC(=O)N3CCCC3)c(C)nc2s1 +O=C(CCCc1ccccc1)Nc1nc(C2CCCO2)n[nH]1 +COc1ccccc1NS(=O)(=O)c1ccc(F)cc1C +COc1ccc(COc2nc(C(C)C)nc(C)c2CCO)cc1F +O=C(OCc1ccccn1)C1(c2ccccc2)CCC1 +CCOC(=O)N1CCN(CCC(=O)Nc2sccc2C#N)CC1 +CS(=O)(=O)NCCNC(=O)CCc1ccc(Cl)c(Cl)c1 +Cc1ccc(NC(=O)CSc2nc(N)cc(=O)[nH]2)cc1C +O=C1NCCN1CCNCc1cc(=O)c2cc(F)ccc2[nH]1 +CNC(=O)Cc1ccc(NCc2csc(-c3ccsc3)n2)cc1 +CCOC(=O)c1cn2ccnc(N3CCOCC3)c2n1 +O=C(NCc1ccc(-n2cncn2)cc1)c1ccncc1F +N#CC1(C(=O)N2CC3CN(Cc4ccncc4)C(=O)C3C2)CC1 +Cc1ccncc1NC(=O)NCCC(=O)Nc1ccccc1 +Nc1ccc(NCCc2ccccn2)cc1C(F)(F)F +Cc1cc(S(=O)(=O)N(C)C)cc(NC(=O)C2CC2)c1C +O=C(C1CCC1)N1CCC2(CC1)Nc1cc(F)ccc1-n1cccc12 +COc1cccc2c1OCC(NC(=O)Nc1ccc3c(c1)COC3)C2 +CC(C)C(Sc1nnnn1C)C(=O)NC1CCCCC1C +CCc1nc(C2CCCN2C(=O)Cn2c(C)cc3ccccc32)no1 +COc1ccc2c(ccn2CCNC(=O)c2ccc3ccn(C)c3c2)c1 +Cc1ccc(NS(=O)(=O)c2ccc(C#N)cc2)c(F)c1 +CCc1cnc(CNC(=O)NCCNC(=O)C2CCCC2)s1 +C=CCCCN(C)C(=O)c1cnc(C2CCCO2)s1 +CC(C)(C)c1nc(CNC(=O)CCCc2cc(F)ccc2F)no1 +COc1ccc(CCNC(=O)NC2CCCC2C)cc1 +CCCNC(=O)c1nnsc1-c1ccc(C)cc1 +O=c1[nH]cnc2c1CCN(S(=O)(=O)c1ccccc1)C2 +O=C(NCc1nc2ccccc2n1CC(=O)N1CCCC1)C1CC1 +COCc1c(C(=O)Nc2ccc(OC)nc2)sc2cccc(F)c12 +CCN(Cc1ccc(OC)cc1)C(=O)c1cc2ccccc2c(=O)[nH]1 +COc1ccc(OC)c(C(=O)CNC(=O)c2ccco2)c1 +Cc1ccsc1CN1CCN(CC(F)F)CC1 +Cc1cc(C(=O)NC(c2ccccc2)c2cccc(F)c2)[nH]n1 +CCCCNC(=O)C1CCCN(C(=O)NCc2cccnc2OC)C1 +Cc1ccc2ncc(C(=O)N3CCCN(CC(F)(F)F)CC3)n2c1 +COc1cccc(C(=O)Nc2ncc(C)s2)c1F +CCOc1nc(N)c(C#N)c(-c2ccc3c(c2)OCO3)c1C#N +COc1ccc(NC(=O)CCc2nc3ccccc3[nH]c2=O)cc1 +COc1ccc(F)c(NC(=O)c2cc(C)nc3c2cnn3C)c1 +O=C(c1cc(CN2CCOCC2)on1)N1CC(Oc2ccccc2)C1 +CCOC(=O)C(N)Cc1ncc(-c2ccc(F)cc2)o1 +CN(CCN1CCOCC1)c1ccc(N)c(F)c1 +O=C(Cc1cccc(F)c1)N1CCC(c2ccnn2CCO)CC1 +Cc1cc(C(O)C2CCCCC2)cc2c1NC(=O)C2 +COc1cccc(-c2cc(CNC(=O)c3ccc4nccn4c3)on2)c1 +O=C(NCCC(O)c1cccs1)c1ccco1 +CC(=O)c1ccc(Cl)c(NC(=O)c2cncc(C)c2)c1 +CC1(C)Cc2cccc(OCC(=O)Nc3ccccc3C(N)=O)c2O1 +C#CCN1CCN(C(=O)NC(C)c2ccc(OC(F)F)cc2)CC1 +COC(=O)N1CCC(NC(=O)c2ccc(=O)[nH]c2)CC1 +CCc1cc(=O)oc2cc(OCC(=O)NCc3cccnc3)ccc12 +CCc1ccc(C(=O)Nc2cccn(C)c2=O)cc1 +Cc1nc(C2CNCCN2C(=O)OC(C)(C)C)cs1 +Cc1cccc(C(=O)Nc2ccccc2-c2nc(C)no2)c1 +Cc1ccc(Cn2c(CO)nc3cccnc32)cc1 +CCCOc1ccccc1NC(=O)c1ccncc1 +COc1ccccc1OC1CN(C(=O)c2ccc(C#N)cc2)C1 +CC(OC(=O)c1cccnc1)C(=O)c1ccc(Cl)cc1 +O=C(Cn1cnc2ccccc2c1=O)NCC#Cc1ccc(F)cc1 +CN(CC(N)=O)c1nc(-c2cccnc2)nc2ccccc12 +CCn1nccc1C(=O)Nc1nc(-c2ccccc2)cs1 +Cc1nnc(SCC(=O)N(C)C2CCCCC2)n1C +Cc1cccc(C(C#N)N(C)C(=O)c2ccc(F)c(F)c2)c1 +Cc1ccncc1NC(=O)NCc1cccc(Cn2ccnc2)c1 +Cc1ccc2c(CC(=O)N3CCC(C(N)=O)C3)coc2c1C +CCN(CC1CCOC1)C(=O)Cn1cnc2c(C)cccc2c1=O +CCC1Oc2cc(O)ccc2N(Cc2ccc(C)cc2)C1=O +CC(=O)N1CCC(=O)N(Cc2ccccc2)c2ccccc21 +CC(C)(C)OC(=O)N1CCN(c2cc(C3CC3)n[nH]2)CC1 +CCN1CC(C)N(C(=O)c2sccc2C)CC1C +C=C(C)Cn1c(CCCNC(=O)C(C)C)nc2ccccc21 +Cn1cc(NC(=O)c2cccc(NC(=O)c3cccs3)c2)cn1 +COC(=O)NC(C(C)=O)c1ccc(O)c(OC)c1 +CC(C)c1noc(CCNCc2ccc3c(c2)OCCO3)n1 +FC(F)(F)c1[nH]c2ncccc2c1CN1CCOCC1 +Cc1cc(Br)ccc1NC(=O)C(C)NS(C)(=O)=O +NC(=O)CCCNC(=O)c1ccc(Oc2ccc(F)cc2F)cc1 +CC(C)(C)CC(=O)N1CCn2c1nc1ccccc12 +CC(Oc1cccc(Cl)c1)C(=O)Nc1ccc2[nH]ncc2c1 +COC(=O)CSc1nnc(COc2ccc(Cl)cc2)n1C +Cc1oc2ncnc(NC(=O)c3ccc(-n4ccnn4)cc3)c2c1C +Cn1nc(C2CCCN(C(=O)Cc3ccsc3)C2)c2nccnc21 +CSc1ccc(NC(=O)NC(C)C(=O)NCc2ccccc2)cc1 +C=CCOc1ccccc1NC(=O)c1nc2nc(C)cc(C)n2n1 +CNC(=O)COc1cccn2cc(-c3cccc(N)c3)nc12 +Cc1ccc(CN2CC(c3nc(-c4cccs4)no3)CC2=O)cc1 +Cc1cc(C)c(C(O)CCC(=O)NCc2cccnc2)c(C)c1 +CCN(Cc1cccc2c1OCCO2)C(=O)c1cnc2ccccc2n1 +CC(=O)Nc1cccc(CNc2ncccc2C#N)c1 +N#Cc1ccc(CN2CCc3cc(F)ccc3C2)o1 +CCn1nc(C)cc1NC(=O)Nc1cccc(OC)c1 +CCn1cc(Cl)c(-c2nnc(-c3ccccn3)o2)n1 +CC(Nc1ncnc2sccc12)C(C)n1cccn1 +Cc1cc(C)c(CNC(=O)Cn2c(C)nc3ccccc32)c(=O)[nH]1 +O=C(c1cc(-c2ccco2)on1)N1CCN(c2ccc(F)cc2)CC1 +N#CC1(C(=O)Nc2c(F)cccc2F)CCCC1 +C=CCCCN(C)C(=O)c1ccc(-n2nc(C)c(Cl)c2C)cc1 +COc1ccc(C(=O)N(Cc2ccncc2)C2CC2)cc1 +Cc1cccc(OC(=O)CCn2cnc3sccc3c2=O)c1C +C#CCNC(=O)c1ccc(OC)c(S(=O)(=O)NC(C)C)c1 +O=C(NCc1ccccc1Cl)c1ccc2ccnn2c1 +Cc1oc(-c2ccccc2)nc1CC(=O)N1CCC(C)CC1 +CN(Cc1ccccc1F)C(=O)c1cc2ccccc2oc1=O +COc1cccc(C(=O)OCC(=O)NC(C)c2ccc(F)cc2)c1 +Cc1ccc(S(=O)(=O)Oc2ccc(-n3cnnn3)cc2)c(C)c1 +COC(=O)c1ccc(CSc2nnc(-c3ccncc3)o2)cc1 +CC(CC#N)N(C)C(=O)Nc1ccccc1OC(C)(C)C +Cc1cc(OCC(=O)Nc2c(C)cccc2C)nc(N2CCCC2)n1 +Cc1noc(C(C)NC(=O)C(C)NC(=O)OC(C)(C)C)n1 +Cc1nnc(NCc2ccccc2Cn2cccn2)c(C#N)c1C +CNC(=O)c1ccc(NC(=O)NCC(C)(O)c2ccsc2)cc1 +CCOC(=O)C1CCN(C(=O)c2ccc(OCC(F)F)nc2)CC1 +N#Cc1nc(COc2ccccc2Cl)oc1NC1CC1 +Cc1cccc(C(=O)NCC(=O)NCC2CCC2)c1 +O=C(NCCc1ccc(O)cc1)c1cc(Br)c[nH]1 +Cc1nnc2sc(-c3ccc(NC(=O)c4ccccc4)cc3)nn12 +COc1cccc2c1ccn2CC(=O)Nc1cnn(C)c1 +CCOC(=O)CCCNC(=O)N1CCOC(c2ccccc2)C1 +CCN(CC)C(=O)CCOc1ccccc1Br +CC(C)CC(=O)NC(C(=O)Oc1cccc(F)c1)C(C)C +CCN(CC)C(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C +Cc1ccc(C(=O)NCC(=O)N2CC(Oc3ccccc3)C2)s1 +Cc1noc(C(C)N2CCN(C(C(N)=O)c3ccc(F)cc3)CC2)n1 +CC(=O)c1c[nH]c(C(=O)Nc2cccc(CN(C)C(C)=O)c2)c1 +CNC(=O)C(CC(C)C)NC(=O)NCc1ccccc1F +O=C(C1CC(=O)N(C2CCCC2)C1)N1CCOCC1 +CC1CCCN(C(=O)Nc2ccc(OCC(N)=O)cc2)C1 +C=CCCN1CCOCC1CC(=O)c1ccccc1 +Cc1nnsc1C(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +Cc1ccc(C(N)=O)cc1NC(=O)NC(C)c1ccc(F)c(Cl)c1 +COc1ccc(C(NC(=O)C2CCC(=O)N2)c2nccn2C)cc1 +COC(=O)C(CC(C)C)NC(=O)c1cc(F)cc2[nH]cnc12 +C=C(C)Cn1nc(C#N)cc1-c1ccc2c(c1)ncn2C +COCC(=O)NCCc1nc2ccccc2n1Cc1ccc(C)cc1 +COCC(C)(NC(=O)c1cscn1)c1ccccc1 +COC(=O)c1ccc2nc(NC(=O)c3c(C)cnn3C)sc2c1 +CCCS(=O)(=O)c1ccccc1NCCC(N)=O +CCSc1ccccc1C(=O)Nc1c(C)cccc1C +C#CCNc1cccc(S(=O)(=O)NC(C)(C)C)c1C +COc1cc(CNC(=O)NCc2ccc(F)cc2)ccn1 +CCN(C(=O)CCc1c(C)nc(SC)[nH]c1=O)c1ccccc1C +Cc1cc(C)cc(-n2ccnc(NC(=O)c3ccco3)c2=O)c1 +O=C(CCC1CCCC1)N1CCN(Cc2cscn2)CC1 +COc1ccc(C(O)CCC(=O)NC(C)(C)C)cc1 +Cc1ccc(NC(=O)Cn2c(C)cc(=O)c3cccc(C)c32)cc1C +O=C(c1ccn2cncc2c1)N(CCO)Cc1ccsc1 +Cc1ccc(-n2nnc(CO)c2-c2ccncc2)cc1C +CCN1C(=O)C(C)(C(=O)Nc2ccccn2)Oc2ccccc21 +CC(C)C(=O)c1ccccc1NC(=O)COc1cccc(C(N)=O)c1 +CN(CC1CCCC1)C(=O)c1cn(C)nc1-c1ccc(F)cc1F +CCCn1nnnc1COc1cc(OC)ccc1C(C)=O +Cc1ccc(C(=O)NC(C(=O)NC2CCCC2)C(C)C)cc1 +CC(=O)c1cc(-c2cc(C)n(C)c2C)n(C(C)C)c1C +CC1Nc2ccccc2N(Cc2ccccc2C#N)C1=O +COCCNC(=O)C1CC(=O)N(c2cccc3ccccc23)C1 +CC(C)NC(=O)C1CCCC(NC(=O)C(C)Cc2ccccc2F)C1 +Cc1nnc2ccc(-c3noc(-c4cc(F)ccc4F)n3)cn12 +COC(=O)c1ccc(C(=O)N2CCNC(=O)C2C(C)C)s1 +CNC(=O)C1COCC2CN(Cc3nccs3)CC21 +Cc1ccc(OCCC(=O)Nc2ccnc(C)c2)c(C)c1 +CN(C)S(=O)(=O)CCNC(=O)c1cccc(-c2ccc(O)cc2)c1 +CCNc1nnc(S(=O)(=O)CC(=O)N(C)c2ccccc2)s1 +CC(C)c1noc(CCNC(=O)C(C)(C)c2ccc(F)cc2)n1 +CC(C)CC(=O)NCCCSc1ccccc1 +CSc1ccc(CC(=O)Nc2c(C(N)=O)oc3ccccc23)cc1 +CC(C)(C)OC(=O)Oc1cccc(-n2cnnn2)c1 +CC(=O)NC1CCCN(C(=O)Cn2c(-c3cccnc3)noc2=O)C1 +COc1cccc(C(=O)Nc2ccc3nc(C4CC4)oc3c2)c1F +Cc1ccc2occ(CC(=O)Nc3ccccn3)c2c1 +CC(C)c1nc(CCN(C)C(=O)CN2CCOC2=O)no1 +Cn1cc(CC(=O)NC2CCCc3ccccc32)c2ccccc21 +CC(C)Oc1cccc(C(C)NC(=O)Nc2cnn(CC(N)=O)c2)c1 +CN(C)C(=O)c1ccc(-c2ccc3c(c2)OCCO3)s1 +NC(=O)c1oc2ccccc2c1NC(=O)c1ccc2c(c1)OCO2 +O=S(=O)(N=c1cccc[nH]1)c1ccc(F)cc1Br +CCc1nnc(CNc2cc(C(=O)N3CCCC3)ccc2OC)o1 +Cc1cc(C)n2cc(CSc3ccccc3N)nc2n1 +Nc1c(-c2cccc(Cl)c2)noc1C(=O)NC1CC1 +CCC1COCCN1C(=O)CSc1cccc(OC)c1 +CC(C)Cc1nn2c(=O)cc(CN(C)c3ccccc3)nc2s1 +CC(C)(C)OC(=O)N1CCCC(NC(=O)c2ccncc2)C1 +COc1ccc(C)cc1NS(=O)(=O)c1ccccc1C#N +N#Cc1cc(N2CCC(n3cncn3)CC2)nc2ccc(Cl)cc12 +COCCOc1ccc(C(=O)N2CCCC(n3cncn3)C2)cc1 +Cc1ccc(CNC(=O)CSc2ncc3ccccn23)cc1 +NC(=O)C(NC(=O)COc1ccc(F)cc1Cl)c1ccccc1 +Cc1c(C(=O)NC(C)(C)C(N)=O)nnn1-c1ccc(F)cc1 +Cc1cc(C(=O)NCc2ccc(Cl)c(Cl)c2)no1 +COCCn1nc(C(=O)N2CCC(c3nc(C)no3)CC2)ccc1=O +CN(CC1(CO)CC1)C(=O)CC1C(=O)NCCN1Cc1ccccn1 +Cc1ccc(C(=O)CCC(=O)N2CC(C)c3ccccc32)s1 +O=C(NCCCN1CCCCCC1=O)Nc1ccc(Cl)cc1F +COc1ccc(-c2cccc(N)c2)n2nc(N)nc12 +CC(=O)Nc1cc(NC(=O)C2CCCC2)ccc1C +COC(=O)c1ccsc1NC(=O)COc1cccc(C)c1 +CC(=O)N1CCCN(C(=O)c2ccc(C(C)(C)C)cc2)CC1 +CCn1nc(C(F)(F)F)cc1C(=O)Nc1c(C)noc1C +CSc1nc(C2CC2)cc(C(=O)NCC(C)C)c1C#N +CCCc1cc(CN(C)C(=O)C2CC(=O)Nc3ccc(F)cc32)n[nH]1 +O=C(NCCc1c(F)cccc1F)c1ccc(-n2ccnn2)cc1 +COc1cc(N)ccc1NC(=O)c1ccc(F)cc1Cl +COc1ccc(CNc2ccc3c(c2)CCN3C(C)=O)cc1OC +COc1cc(C)ccc1NC(=O)CCCCNC(N)=O +CC(O)CC1COCCN1C(=O)NC1CCC(C)C(C)C1 +COc1ccc(NC(=O)N2CCN(C)c3ncccc32)cc1 +O=C(NCCCO)c1ccccc1-c1ncc(-c2ccccc2)o1 +CC(=O)NCCNC(=O)N1CCC(C(O)c2ccccc2)CC1 +Cc1nn(C)c(C)c1C1COCCN1C(=O)c1cc2ccccc2[nH]1 +O=C1CCCN1c1nc(Cc2nc(-c3ccsc3)no2)cs1 +CCCN(CCO)C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C(CCc1ccccc1)N1CCC2C1CCC(=O)N2c1cccnc1 +CC(C)Cn1ncc(C(=O)N2CCOC(C)C2C)c1C1CC1 +COc1ccc(Cl)cc1CN(C)C(=O)Cn1cccnc1=O +COc1cc(-c2nc3c(C)cccn3n2)ccc1O +COCCOCCNC(=O)c1cccc(F)c1Cl +CCS(=O)(=O)N(CC(=O)NC(C)C)c1ccc(OC)cc1 +Cc1cc(C)c(-c2noc(C)n2)c(NC(=O)c2cccs2)n1 +CCCOc1ccc(CNC(=O)Nc2ccc(F)c(C(N)=O)c2)cc1 +Cc1cnc(CNc2cc(-c3ccccc3)nc3ccnn23)cn1 +CN(CC(=O)NCc1ccc(F)cc1)c1ncnc2[nH]cnc12 +c1ncc(CN(CC2CCCO2)C2CCCC2)s1 +CC(C)c1ccc(-c2ccc(C#N)c(=O)n2CCCO)cc1 +CCCS(=O)(=O)N1CCC2(CCN(c3ncccn3)C2)CC1 +Cc1nnc(SCC(=O)N2CC(C)CC(C)C2)n1N +CCCCc1ccc(-n2nnc(C(=O)OC(C)C)c2N)cc1 +Nc1cccc(-c2nc(-c3ccccc3OC(F)F)no2)c1 +CC(C)(C)OC(=O)N1CCN(c2cnccc2C(F)(F)F)CC1 +CN(C)c1ccc(-c2noc(C(=O)NCc3cccc(F)c3)n2)cc1 +COc1ccc(CN(C)C(=O)c2ccc(C)c(C)c2)cc1F +COC1CCN(C(=O)CCn2nc(C)cc2C)CC1 +COc1ccc(C2CCCN2C(=O)NCc2ccoc2)cc1OC +CCN(CC)C(=O)c1ccc(NC(=O)c2ccccc2SC)cc1 +COCc1cccc(CNC(=O)c2ccc(-c3cscn3)cc2)c1 +CNC(=O)NCC(=O)N(C)CCc1ccccc1OC +O=C(c1cnn2c1CCCC2)N1CCc2c1cccc2C(F)(F)F +CC(=O)N1c2ccccc2CC1C(=O)NC1(C)Cc2ccccc2C1 +Cc1ccc(SC(C)C(O)(C(N)=O)c2ccccc2)cc1 +Cc1sc(NC(=O)CSc2n[nH]c(N)n2)c(C#N)c1C +CCc1noc(CN(CC)C(=O)C(C)n2cnc3ccccc32)n1 +C=CCNC(=O)CNC(=O)Nc1ccc(Cl)c(Br)c1 +O=C(NCC(O)c1cc(F)ccc1F)c1cccs1 +CC(C)(C)c1oc(C(N)=O)cc1CN1C(=O)CCc2ccccc21 +CC(C)CC1COCCN1C(=O)c1ccsc1 +CCC(NC(=O)c1ccc2[nH]nnc2c1)c1ccc2c(c1)OCCO2 +Cn1ncc(N2CCCC(C(=O)NCc3ccco3)C2)cc1=O +CC(C)CCNC(=O)c1cccc(-c2nnco2)c1 +COC(C(=O)Nc1cc(Cl)ccc1NC(C)=O)c1ccccc1 +CSc1nc(C(C)C)nc(C)c1C(=O)NCCNC(C)=O +CCOc1ccc(C2=CCN(C(=O)c3cn4cccnc4n3)CC2)cc1 +CN(C)c1ccc(-c2nnn(CC(=O)N3CCCC3)n2)cc1 +COC(=O)C=C(CC(=O)OC)C(F)(F)C(F)(F)F +COCc1ccccc1NC(=O)N(C)Cc1ccccc1F +Cc1cc(=O)n(CC(=O)N2CCc3ccccc3C2)cn1 +Cc1nn2cccnc2c1C(=O)Oc1cc(F)ccc1F +CNc1nc(N2CCCCC2)nc2c1C(=O)CCC2 +Cc1nc(SCc2nnc(C3CC3)n2C2CC2)[nH]c(=O)c1C +CC(O)C(Cc1ccccc1)(OC(N)=O)C(N)=O +Cc1ccc(S(=O)(=O)NCCO)cc1C(=O)NC1CCCCC1 +CC(C)NC(=O)CNC(=O)c1ccc2c(c1)CCO2 +CCC1Nc2cc(C)c(C)cc2N(CC(=O)NCCOC)C1=O +CN1CCC(C(=O)Nc2cccnc2N(C)C)CC1=O +CCCN1CCN(C(=O)CCc2c(C)nn3cnnc3c2C)CC1 +Cc1nc(C)c(C(=O)Nc2ccc(C(C)C)cc2)s1 +Cc1csc(C2(NC(=O)CCn3cncn3)CCCCCC2)n1 +O=S(=O)(Nc1cccc2cccnc12)N1CCOCC1 +Cc1nc(C(=O)Nc2ccccc2C(F)(F)F)n(C)c1C +COCc1ccc(C2CCCN2C(=O)NC2CCCC3OCCC23)o1 +O=C(NCCc1cc2ccccc2o1)Nc1cnn(-c2ncccn2)c1 +Cc1cc(CN2CCN(C(=O)CCc3ccccc3Cl)CC2)no1 +Nc1cccc(OCc2cn3cc(Cl)ccc3n2)c1 +O=C(Cc1ccc(F)c(F)c1)NCc1nc(-c2ccncc2)cs1 +Nc1nonc1-c1nnc(Cc2ccccc2F)o1 +Cc1ccccc1NC(=O)CCC(=O)Nc1ccccc1C +CCCc1n[nH]c(Sc2cc(C)nc(COC)n2)n1 +O=C(NCc1ccccn1)NC(c1ccc(F)cc1)C1CCCO1 +Cc1cc(NC(=O)c2cn(C)nc2C(C)(C)C)ccn1 +N#Cc1nnn(CCCCOc2ccccc2)c1C1CCCO1 +CC(=O)Nc1ccc(OC(=O)Cc2ccc(O)cc2)cc1 +Cc1cc(-c2cn3cc(CO)ccc3n2)ccc1Cl +CC(c1cccnc1)N(C)C(=O)Cc1ccc(F)cc1F +COCc1nc2cc3c(cc2n1CCCO)OCCO3 +C=CCNc1nc(-c2ccc3c(c2)CC(=O)N3C)cs1 +CCc1nnc(C(=O)Nc2cccc(C(=O)N3CCCCC3)c2)s1 +CC(=O)Nc1ccc(CN(CC(F)F)C2CC2)cc1 +CC(NCc1noc(C2CCOCC2)n1)c1cc2ccccc2o1 +Cn1cc2cc3c(Nc4ccccc4F)ncnc3cc2n1 +O=C(OCc1ccccc1F)C1CCCN1C(=O)c1ccco1 +CCOC(=O)c1c(C)c(C(=O)NCCC(C)C)c(C)n1C +N#Cc1ccccc1NC(=O)CCN1CCOC1=O +COC(=O)c1cnc(NC(=O)COc2ccccc2C)s1 +CCCNC(=O)CN1CCN(C(=O)c2ccc3c(c2)CCC3)CC1 +Cn1nc(C2CC2)cc1NC(=O)NCCN1CCNC1=O +Cc1cnc2c(c1)N(S(=O)(=O)Cc1ccon1)CCO2 +Cc1cc(C)n2ncc(C(=O)NC(C)Cc3cccc(Cl)c3)c2n1 +Cc1nn(C)c(C)c1CCC(=O)N1CCCc2ccc(F)cc21 +O=C(Nc1ccc(Br)cn1)C1CC2C=CC1C2 +Cc1cc(C(=O)Nc2ccc(Oc3ncccc3C#N)cc2C)n(C)n1 +C#CCN1CCN(C(=O)NC(C)c2ccc(F)c(Cl)c2)CC1 +COC1CCCN(C(=O)CCc2cccc(F)c2)C1 +CCC(C)n1ncc(C(=O)N(C)Cc2ccncc2)c1C1CC1 +Cn1cnc(CNC(=O)c2ccc(OCc3ccccn3)cc2)n1 +C#CCNC(=O)C(C)N1CCN(c2nc3ccccc3s2)CC1 +CC(=O)NC1CCN2C(=O)C(Cc3cccs3)NC(=O)C12 +CCCCN(C)C(=O)C1CCN(C(=O)NCc2cscn2)CC1 +CCCc1ccc2c(c1)C(c1ccnnc1)NCC2 +O=C(NCCN1CCNC1=O)C1CCN(c2ccccc2)C1=O +CC(=O)NC(C)C1NCCc2c1ccc1cc[nH]c21 +CS(=O)(=O)c1ccc(F)c(NCc2ccc(F)cc2)c1 +Cc1cc(C)nc(SCC(=O)Nc2ccc(F)c(C#N)c2)n1 +O=C(CCCNC(=O)c1ccco1)Nc1ccccc1C(F)(F)F +O=S(=O)(Nc1ccccn1)c1ccc2ccccc2c1 +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)NCCCO +O=C(c1csc2c1CCCC2)N1CCCC(O)C1 +CC(=O)NC1(C(=O)N2CCCC2Cn2cc(C)cn2)CCC(C)CC1 +COCCN1CC(C(=O)Nc2cccc(Cl)c2C)CC1=O +Cc1cc(C)cc(-n2c(C)cn3c4c(=O)n(C)c(=O)n(C)c4nc23)c1 +Nc1ccc(NC(=O)Cc2cccs2)cc1C(F)(F)F +Cc1cc(C(=O)NCC(=O)NC2CCC(O)CC2)c(C)o1 +CCOc1ncccc1CNC(=O)NC(C)c1cc(C)sc1C +NC(=O)Nc1ccc(CNC(=O)CC2C=CCC2)cc1 +CNC(=O)c1cc(NC(=O)c2ccc(OC)nn2)ccc1F +COc1cc(C)c(C(O)Cn2cc(N)cn2)cc1C(C)C +CC(=O)Nc1nc(C)c(S(=O)(=O)N2CCN(C)CC2)s1 +CC(C)(C)C(O)CCNC(=O)Cc1ccccc1Cl +COCCOc1ccc(NC(=O)NC(C)c2cccs2)cc1 +CN(Cc1nc2cc(Cl)ccc2c(=O)[nH]1)Cc1ccccc1F +CCOC(=O)c1cn(-c2cccc(C)c2)c(=O)c2ccccc12 +Cc1sc(-c2ccn[nH]2)cc1NC(=O)c1ccco1 +CN(C)C(=O)COc1cccc(NC(=O)CC2CCCCC2)c1 +CCCC(=O)N1CCN(c2nc3c(F)cc(F)cc3s2)CC1 +NC(=O)NCCC(=O)NCc1ccccc1CN1CCCC1=O +Cc1nnc2n1CC(NC(=O)COCC(F)(F)F)CC2 +COc1ccc(C2CCCCCN2C(=O)C(C)n2cncn2)cc1 +O=C(NCCNc1ncccn1)c1ccc(Br)cc1O +O=C(Cn1ccc(=O)c2ccccc21)Nc1nc2ccc(F)cn2n1 +CC(C)Nc1cccc(CNC(=O)c2ccc[nH]c2=O)c1 +CC(C)CCC(=O)N1CCN(C(=O)Nc2ccc3c(c2)CCC3)CC1 +CN(C)C(=O)N1CCN(c2cc(N3CCCC3CO)ncn2)CC1 +CCCn1nc(C(=O)Nc2cccnc2)ccc1=O +CCC(c1cccnc1)N(C)C(=O)c1ccccc1-c1ncc[nH]1 +CSc1ccc(OC(C)C(=O)NCC(C)N2CCOCC2)cc1 +CCn1ncc(S(=O)(=O)Nc2ccc(C(=O)OC)cc2)c1C +O=C(c1cccc(F)c1)N1CCN(Cc2ccccn2)CC1 +O=C(CCSc1ccccc1)NCc1ccsc1 +CCS(=O)(=O)c1ccccc1C(=O)NCC(=O)OC +CC(C)CNC(=O)C(C)Nc1c(-c2ccsc2)nc2ccccn12 +CC#CCSc1ncnc2c1cnn2-c1ccccc1 +COc1ccc2oc(C)c(C(=O)NCc3ncn(C)n3)c2c1 +CC1CC1C(=O)N1CCN(c2oc(C3CC3)nc2C#N)CC1 +Cc1cnc(NC(=O)C2CCCN(C(=O)c3ccc(F)cc3)C2)s1 +Cc1ccc(-c2c3c(=O)n(C)c(=O)n(C)c3cn2-c2ccccc2)cc1 +CC(Cc1ccc(Br)cc1F)NS(=O)(=O)N(C)C +CC1(C2CC2)Nc2ccccc2C(=O)N1CCc1ccccc1 +COC(CNC(=O)N1CCOCC1)c1ccc(Cl)cc1 +CCCC1CN(C(=O)c2ccc(COC)cc2)CCO1 +Cc1ccc(N(C)C(=O)C(C)NS(=O)(=O)c2cnn(C)c2)cc1 +O=C(NCCNC(=O)c1cccc(-c2ccoc2)c1)c1cccnc1 +CCc1nc(CS(=O)(=O)c2ccc3ccccc3c2)no1 +CC(=O)Nc1ccc(NC(=O)c2cccnc2)cc1 +O=C(Cn1cc(C2CC2)nn1)Nc1ccnc(Oc2ccccc2)c1 +CC1(C)C2CC=C(COC(=O)c3cccnc3)C1C2 +CCC1CCCCN1C(=O)C(C)n1nnc(-c2ccccc2)n1 +N#CCCN(Cc1cccnc1)C(=O)CC12CC3CC(CC(C3)C1)C2 +CC(CNC(=O)c1cc(F)cc2[nH]cnc12)Oc1ccccc1 +COC(=O)c1cccc(CCNC(=O)c2cc(C(N)=O)cs2)c1 +Cc1cc2cc(CNC(=O)c3ccccc3)ccc2n1C +Cc1ccccc1CC(C)(C)NS(=O)(=O)c1cc(C(N)=O)n(C)c1 +C=CCOC(=O)c1sc(NC(=O)c2ccc(Cl)cc2)nc1C +CC(C)N(C)S(=O)(=O)NCc1cc(Br)ccc1F +O=C1CCCN1Cc1nnn2c1CN(C(=O)C1CC=CC1)CCC2 +COc1cccc(C(=O)Nc2cccc(N3CCCNC3=O)c2)c1F +Cc1cnn(CCC(=O)Nc2cc(Br)c(=O)n(C)c2)c1 +CSc1ccc(CN(C)C(=O)c2cc(C)oc2C)cc1 +CC(C)(CNC(=O)C(c1ccccc1)N1CCCC1)c1ccncc1 +CCCn1cc(N)cc1C(=O)NCc1ccc(C)s1 +CN(CC(N)=O)C(=O)CCc1ccc(Br)cc1F +CCCCC(=O)NCc1cccc(C(=O)NC2CC2)c1 +O=C(c1nc2ccccc2s1)N1CCN(Cc2ccsc2)CC1 +Nc1nc(-c2cc(F)ccc2F)ccc1C(=O)NC1CC1 +O=C(c1nc(-c2cccs2)n(-c2ccccc2)n1)N1CC(O)C1 +CCN(CC(=O)NC(C)C)C(=O)Cc1ccc2ccccc2c1 +Cc1csc(C(C#N)C(=O)c2cccc(OCC(=O)N(C)C)c2)n1 +C=CCn1c(-c2ccc(C)cc2C)ccc(C#N)c1=O +Cc1nc(N2CCNC(=O)CC2C)c2c3c(sc2n1)CCC3 +CC(C)n1cnnc1S(=O)(=O)Cc1ccc(C(C)(C)C)cc1 +CCCCCNS(=O)(=O)c1ccc(C#N)c(Cl)c1 +COc1ccc(C(C#N)NC(=O)c2ccco2)cc1 +CCCc1noc(COc2ccc(-c3noc(C)n3)cc2)n1 +Cc1cc(C)c2c(c1)cc(C)c1nn(CC(=O)N(C)C)c(=O)n12 +COCCN(Cc1ccc(C)o1)C(=O)Nc1ccc(OC)c(F)c1 +Cc1noc(C(C)OC(=O)C(C)OCc2ccccc2)n1 +CC(NC(=O)c1cccc(F)c1)c1ccc(S(C)(=O)=O)cc1 +Cc1ccccc1SCC(=O)Nc1cccc(-n2cnnc2)c1 +O=C(CCC(=O)N1CCSc2ccccc21)NC1CCCC1 +Cc1nn(CC(=O)NCc2cccc(Cl)c2)c(N)c1C#N +Cc1ccccc1C(C)NC(=O)c1ccc(S(=O)C(C)C)cc1 +CC(C)Cc1cc(NC(=O)CNC(=O)c2ccsc2)n(C)n1 +CCc1noc(CN(Cc2ccccc2C(F)(F)F)C2CC2)n1 +N#Cc1ccc(N2CCN(c3ncccc3Cl)CC2)nc1 +COC(=O)c1[nH]nc(-c2cccc(OC)c2)c1Br +CNC(=O)c1ccc(F)c(S(=O)(=O)N2CCC2)c1 +O=C(COC(=O)c1ccco1)Nc1ccc2c(c1)OCO2 +NC(=O)C1CCN(c2nc3sccn3c2CO)CC1 +Cc1cc(C)n(-c2ccc(C(=O)NC3CC3)nn2)n1 +Cc1cc(NS(=O)(=O)c2ccccc2F)ccc1N1CCCC1=O +Cc1ccnc(Nc2nc(-c3c(C)nc4ncccn34)cs2)c1 +Cc1cc(C(=O)NCc2cccc(NC(=O)Cn3cccn3)c2)no1 +Cc1noc(C(C)OC(=O)c2cccnc2OCC(F)F)n1 +COc1ncnc2c1CN(Cc1cnn(-c3ccc(F)cc3)c1)CC2 +CCC(C(=O)NC(C)C)N(c1ccc(Cl)cc1)S(C)(=O)=O +O=C1CCc2cc(NC(=O)c3ccc4ccccc4n3)ccc2N1 +O=C(c1ccccc1)N1CCC(Oc2cnc3ccccc3n2)CC1 +O=C(CNC(=O)OCC(F)(F)F)Nc1cccc2c1CCCC2 +COc1ccc(C#CCNC(=O)Nc2ccc(OC)cc2OC)cc1 +O=C(Cc1ccccc1Cl)N1CCN(C(=O)NCC2CC2)CC1 +C=CCNC(=O)N(C)CCOc1ccccc1OC +Nc1c(O)n[nH]c1CCc1ccccc1Br +O=S(=O)(Cc1ccc(F)cc1)N1CCN(C2CC2)CC1 +CCOc1ncccc1C(=O)Nc1cc(C(C)(C)C)nn1C +Cn1c(=O)n(C2CCCN(Cc3ccc(C#N)cc3)C2)c2ncncc21 +c1csc(CNCC2OCCc3cn(CC4CCOCC4)nc32)c1 +Cn1ccc(NS(=O)(=O)c2cccc3cnccc23)n1 +Cc1nn(C)cc1CN(C)C(=O)C1COc2ccccc2C1 +Cc1cc(-c2nnc(CCC(=O)N3CCCCCC3)o2)n(C)n1 +CN(C)C(=O)c1cccc(NC(=O)COc2ccc3ncccc3c2)c1 +CCc1cc(CN(C)C(=O)C(O)c2ccc(Cl)cc2)on1 +CC(O)CN(C)C(=O)C(C)Oc1cccc(F)c1 +COCC(=O)N(C)Cc1cc(Br)cs1 +CCCC1CN(C(=O)c2ccc(-n3cccn3)cc2)CCO1 +CC(NC(=O)C1CC1c1ccco1)c1cccs1 +CCC(=O)Nc1ccc(C2(C(=O)NC3CC3)CCCCC2)cc1 +CCCc1nc(CSc2nnnn2CC2CCCO2)cs1 +COc1ccc2ccn(CC(=O)NCc3ccccc3F)c(=O)c2c1 +Cc1ccc(NC(=O)C2CCCN2c2ncccn2)c(O)c1 +CCOC(=O)c1ccc(N2CC(C(=O)OCC)CC2=O)c(Cl)c1 +C=CCN1C(=O)C(Cc2cccc(C)c2)Oc2cc(N)ccc21 +CCOC(C)c1nccn1Cc1ccc(Br)cc1F +COc1ncccc1C(=O)NC1CCOc2ccccc21 +CCc1ccc(-n2nc(C(C)=O)c(=O)cc2C)cc1 +CC(C)N(C(=O)Cn1nnc(-c2ccccc2)n1)C1CCC1 +NC(=O)C1Cc2ccccc2N1C(=O)COc1ccc(F)cc1 +COC(=O)N1CCC(NC(=O)C23CC4CC(CC(C4)C2)C3)CC1 +Cc1cc(NC(=O)C(C)N2CCn3c(C)nnc3C2)no1 +CC(=O)c1cccc(S(=O)(=O)N(C)CC(=O)NC(C)(C)C)c1 +Cc1cc(C)n(Cc2cccc(Br)c2)n1 +CN(Cc1cscn1)c1cc(Cl)ccc1C#N +O=C(COc1ccc(Br)cc1)N(CCO)CCO +COc1ccc2cc(CNC(=O)Cn3nc(C)cc3C)ccc2c1 +CCOC(=O)N(C)c1ccc(NC(=O)N(CC)CC)cc1 +CC(=O)Nc1ccc(C(=O)NCc2ccc(OC(C)C)cc2)cc1 +CC1=NC(c2ccc(Cl)cc2)=CC1C(=O)N1CCCC1 +CS(=O)(=O)Oc1ccccc1CS(N)(=O)=O +O=C(NCCCNc1ccccc1)c1cc2ccccc2c(=O)[nH]1 +Cc1nn(CCC(=O)NC2CCCCC2)c2ccccc12 +COc1ccc(C(=O)NCc2cc3n(n2)CCN(C(=O)N(C)C)C3)o1 +NC(=O)c1cc(NC(=O)C2CCC2)ccc1Cl +COCCN(Cc1ccccc1)C(=O)C(C)NC(N)=O +CC(=O)c1ccc2c(cnn2C(=O)OC(C)(C)C)c1 +CC(NC(=O)C1CCC1)c1ccc(-n2cccc2)cc1 +C=CCNC(=O)c1ccc(-c2cccs2)nc1N +O=C(c1cc(-c2ccncc2)[nH]n1)N1CCOCC1 +Cc1ccc(SCc2nc(CN)cc(=O)[nH]2)cc1 +O=C(CCCOc1ccc(F)cc1)Nc1nnc(-c2ccco2)s1 +CC(=O)Nc1c(C)cc(NC(=O)N2CCCC3CCCC32)cc1C +Cc1ccccc1Cn1c(=O)cc(O)c2ccc(N)cc21 +CC1CN(Cc2ccnn2C)CC(c2ccc(F)cc2)O1 +CCS(=O)(=O)NC1CCN(C(=O)c2scnc2C2CC2)CC1 +Cc1c(NC(=O)COc2ccc(C(C)(C)C)cc2)cnn1C +NS(=O)(=O)c1ccc(CCNc2ncnc3[nH]ncc23)cc1 +CN(Cc1ccccn1)C(=O)c1ccc(=O)n(C)c1 +CCOC(=O)N1CCC(OC(=O)Cc2ccc(C)cc2)CC1 +Cc1nnc(NC(=O)NC2CCCNC2=O)s1 +O=C(COC1CCCCC1)NCc1cc(Br)cs1 +CCCNC(=O)CNC(=O)CNC(=O)C1CCCC1 +C=CCCOC(C)C(=O)N1CC(c2ccccc2C)CC1C +Cn1ccc(NS(=O)(=O)c2cccc(C(N)=O)c2)n1 +CCSc1nc(C)cc(C(=O)Nc2c(C)nsc2C)n1 +COC(=O)CNc1ccc(CC(=O)N(C)c2ccccc2)cc1 +O=C(Nc1ccncc1)C1CCN(C(=O)c2ccoc2)CC1 +OCc1ccc(-c2nccn2-c2cccc(-c3ccn[nH]3)c2)o1 +COc1ccc(CN2CCOCC2c2ccc(C)o2)cc1SC +CCn1ncc2c1C(COC)CN(S(C)(=O)=O)C2 +CN(C)S(=O)(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +COc1cc(CNCCc2ccccn2)cc(Br)c1O +C=CCN(CC=C)C(=O)NCc1ccc(C(=O)N(C)C)cc1 +N#Cc1cccnc1N1CCN(C(CO)CO)CC1 +CC(=O)N1CC(C(=O)N2CCCC2)Oc2ccccc21 +CCOC(C)C(=O)N1CCC(NC(=O)c2cc(C)on2)CC1 +O=C1NC(c2ccc(F)cc2)c2c1oc1ccccc1c2=O +CC1Cc2ccccc2N1C(=O)c1cnc2n(c1=O)CCS2 +CCC(C)NC(=O)C(C)NC(=O)c1ccc(C(=O)N(C)C)cc1 +CC(=O)N1CCCC2(CC(OCc3ccncc3)CO2)C1 +O=C(NCCN1Cc2ccccc2C1=O)Nc1cccc(Cl)c1 +CC(C)Cn1c2c(ccc1=O)CC(NCc1ccoc1)CC2 +NC(=O)Cn1ccc(NCc2nc(-c3ccsc3)no2)n1 +Cc1nc(C2CN(CCOc3cccc(Cl)c3)CCO2)no1 +COc1cccc2c1C(C=Cc1ccco1)NCC2 +Cc1nn(-c2ccccc2)nc1C(=O)NCCCNS(C)(=O)=O +CCOC1CCCN(C(=O)CCc2cc(Cl)cs2)C1 +Cc1cccc(NC(=O)CSc2nncn2C)c1C +Cc1ccc(S(=O)(=O)N(CC(=O)N(C)C)c2ccccc2C)cc1 +Cn1c(C2CC2)cc2ccc(Br)cc2c1=O +COC(C)C(=O)NC(C)C(=O)NCc1ccco1 +CCC(CC)NC(=O)c1ccc2c(c1)CCCN2S(C)(=O)=O +COC(=O)c1cnn(-c2cccc(Cl)c2Cl)c1N +CCC(=O)Nc1nn(C)c2nc(C)c(Cl)c(C)c12 +Cc1[nH]ncc1CCCNC(=O)c1ccnc(-n2cncn2)c1 +O=C1OCCCN1CCn1cnc2sc3c(c2c1=O)CCNC3 +COCCCN(C)S(=O)(=O)c1cccc(F)c1C#N +N#CC1(C(=O)N2CCC3(CC2)OCCO3)CCCC1 +COc1ccc(Br)cc1CC(O)c1cnccn1 +O=C(c1ccccc1)N1CCCC1c1nc2ccccc2s1 +CCOC(=O)COc1ccc2c(=O)c(Cl)coc2c1 +CNc1ccc(S(=O)(=O)Nc2cc(C)nn2C)cc1 +O=C(NCCCn1ncc2ccccc21)c1ccco1 +COc1cccc(NC(=O)Cn2c(C)cc(C)c(C#N)c2=O)c1 +Cc1cccc(C(=O)NCC(=O)Nc2ncc(C)s2)c1 +O=C(CNC(=O)c1n[nH]c2cc(Cl)ccc12)NC1CC1 +CC(NS(=O)(=O)c1cccc(F)c1)c1ccc2c(c1)OCCO2 +O=C(CNc1cc(F)cc(F)c1)NCCOc1ccccc1 +Cc1cccnc1CC(C)Nc1nc2c(s1)c(C)nn2C +CC(C)Cn1ncc(C(=O)N2CCN(C)CC2C(C)C)c1C(F)F +COCCCNC(=O)c1csc(Nc2cccnc2)n1 +Nc1ccc(Cl)c(C(=O)OCCOc2ccccc2)c1 +Nn1c(SCc2ccccc2)nc2ccccc2c1=O +COC(=O)CC1CCCCN1C(=O)c1ccsc1 +CC(Oc1ccccc1Cl)C(=O)Oc1ccc(-n2cnnn2)cc1 +Cc1nc(CC(=O)N2CCC(Cc3cccc(C(N)=O)c3)C2)cs1 +O=C(NCCCSc1ccc(F)cc1)Nc1ncccn1 +Cn1cnnc1C1CCN(c2ccc(C#N)cn2)CC1 +COc1cc(C)ccc1OCC(=O)Nc1ccc(C)c(NC(C)=O)c1 +Cc1nnc(NCC(=O)c2ccc3c(c2)OCCO3)s1 +O=C(Nc1ccccc1F)C1(c2ccccc2)CC1 +O=C(NCCc1nc(-c2ccncc2)cs1)c1ccc(F)cc1 +Cc1cc(CN(C)C(=O)Nc2cccc(-n3nnnc3C)c2)no1 +Cc1c(NC(=O)CCN2CCCS2(=O)=O)sc2c1CCCC2 +Cc1ccc(NCc2cc(C#N)ccc2F)cc1O +Cc1cc2ncc(C(=O)Nc3cccc(OCC(N)=O)c3)c(C)n2n1 +CCCc1nc(C(C)(C)NC(=O)c2cnc(CC)s2)no1 +COc1cccc(N2CC(C(=O)Nc3cccc(C)n3)CC2=O)c1 +CC(CNC(=O)CCn1ccccc1=O)Oc1ccc(Cl)cc1 +Cc1nc2c(s1)C(N(C)Cc1ccc(S(C)=O)cc1)CCC2 +CNS(=O)(=O)CC(=O)NC(C)c1csc2ccccc12 +CN(CC1CC1)C(=O)c1ccc(-c2cccs2)[nH]c1=O +COc1ccccc1-c1nc(NC(=O)c2sc(C)nc2C)n[nH]1 +N#Cc1ccc(C(F)(F)F)c(NCC2CC(=O)N(C3CC3)C2)c1 +CCC1CN(Cc2ncccc2C)CCC(=O)N1Cc1ccccc1 +CC(CCc1ccccc1)NC(=O)Cn1ncc2ccccc21 +O=C1c2ccc3ccccc3c2CN2C(=O)CCC12 +CC=Cc1ccc(OCC(=O)Nc2nc3ccccc3[nH]2)c(OC)c1 +CN(c1ccccc1)C1CCN(C(=O)CNC(=O)CC(C)(C)C)CC1 +CNc1nc(CNC(=O)Nc2ccnc(C(=O)N(C)C)c2)cs1 +CN1CC(C(=O)N(Cc2ccccc2F)C2CC2)CC1=O +Cc1cccc(C(=O)NCC2COC3(CCCC3)O2)c1 +CC(CC#N)N(C)Cc1cnc(-c2ccsc2)s1 +CCCC(C)N1CC2(CCN(C(=O)c3cc(C)no3)CC2)OC1=O +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NCCNC(=O)C1CC1 +CC(NCc1cnn(C(C)(C)C)c1)c1ccc(S(C)(=O)=O)cc1 +CN(C)C(=O)c1ccnc(NC(=O)c2cccc(-c3ccoc3)c2)c1 +Cc1ccc(-c2nnc3ccc(-n4cc(C)cn4)nn23)cc1 +Cn1c(SCC(=O)NC(C)(C)C)nnc1-c1ccccc1 +CCCS(=O)(=O)c1ccccc1C(=O)NCCOC +O=C(COc1ccc2c(c1)OCO2)Nc1ccccc1Cl +Nc1cccc2c1CS(=O)(=O)N(C1CCCCC1)C2 +C#Cc1cccc(NC(=O)N2CCN(Cc3cccc(C)c3)CC2)c1 +CCCS(=O)(=O)NCC1CCN(C(=O)Oc2ccccc2)CC1 +Cc1ccc(NC(=O)N2CC(C)OC(C)C2)cc1C +Cn1ncc2c(N3CCOCC3)nc(NC3CCCCCC3)nc21 +Cc1cc(N2CCCCC2)nc(CNC(=O)C2CCCCC2)n1 +CN(c1ccccc1C(N)=O)S(=O)(=O)c1cccc(F)c1F +CCOc1ccc2c(c1)CCCN2S(=O)(=O)CC#N +COC(=O)C1(N(C)Cc2cnc(C3CCC3)s2)CCCCC1 +Cc1cc(S(=O)(=O)NC2(CO)CC2)sc1C +O=C(NCc1cccnc1)c1cnc(N2CCOCC2)c2ccccc12 +COc1ccccc1-c1nc2ccccc2n1CCC#N +CC(=O)c1cccc(NC(=O)c2cc(F)ccc2-n2cnnn2)c1 +Nc1ccc(Nc2cccc3ncccc23)c(F)c1 +O=C(Cn1c(=O)cnc2ccccc21)OCc1nncn1C1CC1 +Cc1cccc(OCCCN2CCCS2(=O)=O)c1 +CC(C)Cn1ncc2cc(C(=O)Nc3cnn(CC(F)F)c3)cnc21 +CCn1ccnc1CN1CCCN(C(=O)CCc2ccsc2)CC1 +COC(=O)N1CCC(NC(C(=O)NC2CC2)c2ccccc2)CC1 +N#Cc1ccc(NCc2ccc(OC(F)(F)F)cc2)nc1 +CC(NC(=O)c1ccco1)C(=O)NC1CCN(S(C)(=O)=O)CC1 +CC(=O)N1CCN(C(=O)CCc2ccco2)CC1 +Cc1nc(Nc2ccccc2C)cc(C2CCN2S(C)(=O)=O)n1 +Cn1cnnc1SCC(=O)c1cccc(N2CCCC2=O)c1 +CCCc1nnc(NC(=O)Cc2coc3ccc(C)cc23)s1 +CC(C)COc1cccc(C(=O)Nc2cccc(N)c2)c1 +CCCC(=O)NCc1csc(NC(=O)CCC)n1 +N#Cc1cccc(CNC(=O)Nc2ccc(NC(=O)C3CC3)cc2)c1 +C=CCNC(=O)C1CSc2nc(C(C)(C)C)cc(=O)n2C1 +CCCC(C)C(=O)Nc1cc(S(=O)(=O)N(C)C)cc(C)c1C +COc1ccc2c(c1)CCCN2C(=O)Cn1nc(C)nc1C +N#Cc1ccccc1NC(=O)CSc1nc2c(cc1C#N)CCC2 +O=S(=O)(Cc1noc(C2CC2)n1)c1nccn1-c1cccc(F)c1 +CC(C)S(=O)(=O)N1CCCC(c2nccn2Cc2ccccn2)C1 +Nc1c(Cl)cccc1C(=O)NCCN1CCOCC1 +CN(C)c1ccc(C(=O)Nc2nc3cc4c(cc3s2)OCO4)cc1 +O=C(CCC1CCCOC1)N1CCCc2cccc(O)c21 +CC(C)Cn1cc(C(=O)N(C)C2(C#N)CCC2)c2ccccc21 +CCOC(=O)CCC(C)NC(=O)c1cc(C)ccc1F +C=CCN(CC#Cc1ccccc1)C(=O)C1C=CC=N1 +Cc1cc(CS(=O)(=O)N2CCCC(O)C2)no1 +COc1ccc(O)c(C(=O)N(C)Cc2ccc(C)o2)c1 +CN(C)c1ccc2c(=O)c(CCC#N)c(C(F)(F)F)[nH]c2c1 +Cc1cc(C)cc(CSc2nnc(-c3ccoc3C)n2N)c1 +COc1ccc(N(C)S(=O)(=O)c2ccc3c(c2)CCO3)cn1 +COc1cccc(NCc2cccc(F)c2OC)n1 +CC(=O)OCC(=O)NC(c1ccccc1)c1ccc(Cl)cc1 +CC(Sc1ccccn1)C(=O)OCCC(F)(F)F +CC(C)NC(=O)c1cc2cnn(C3CCCCC3)c2nc1N +CCC1CCC(NC(=O)Cn2c(=O)[nH]c3ccccc3c2=O)CC1 +CC(C)NC(=O)Nc1ccccc1C(=O)N1CCC1 +CC(C)N(Cc1ccccc1)C(=O)c1cccc2c1NC(=O)C2 +COC(=O)C(C)CN(C)C(=O)c1cc(C)ccc1C +COCCN(Cc1ccco1)C(=O)c1cnns1 +O=C(NCCCc1nc(-c2cc3ccccc3o2)no1)C1CC1 +CCCOC(=O)c1ccc(NC(=O)NCc2ccccn2)cc1 +COCCc1ccc(OC(=O)C2CCOCC2)cc1 +COc1cccc(C(=O)Nc2ccc(N3CCOCC3)nc2)c1 +Cc1ccccc1N1CCCN(C(=O)c2ccc(O)cc2)CC1 +CCOC1CC(OC(=O)C2CCN(C)C(=O)C2)C1(CC)CC +O=C1CCN(C(=O)COc2ccc3c(c2)CCC(=O)N3)CCN1 +CC(C)S(=O)(=O)NCc1noc(-c2cccs2)n1 +CCOCC1CN(C(=O)CCc2ccccc2)Cc2cn(CC)nc21 +CC(NC(=O)CN(C)c1ncnc2[nH]cnc12)c1cccs1 +CCN(CC)C(=O)CSc1nnc(-c2ccc(N)cc2)n1C +CCCOC(=O)C(NC(=O)c1ccc(C)cc1)C(C)C +O=C(c1ccccc1)N1CC=C(c2c[nH]c3ccccc23)CC1 +Cc1noc(C)c1C(C)NS(=O)(=O)c1ccc(C#N)c(Cl)c1 +Cn1nnc(NC(=O)c2ccc(-c3cccc(Cl)c3)o2)n1 +Cc1cc2c(=O)n(Cc3csc(C)n3)cnc2s1 +CNS(=O)(=O)c1ccc(C(=O)NCCc2cc(C)cc(C)c2)cc1 +O=C(Nc1ccc(F)c(NC(=O)C2CCCCC2)c1)NC1CC1 +CC(O)CNc1ccc(NC(=O)c2ccc(Cl)cc2)cn1 +CCCS(=O)(=O)NC1CC(C)N(c2ccccc2)C1=O +N#Cc1cn(-c2ccccc2)nc1-c1cc2ccccc2oc1=O +O=C(Nc1ccc2c(c1)C(=O)NCC2)c1ccc(F)cc1 +COc1ccc(C(=O)c2c(C)n(C)c(=O)n(C)c2=O)cc1 +O=C1CC2OC(=O)CC2C(COCc2ccccc2)O1 +Cn1nc(C(=O)NC2CCCC2)cc1NC(=O)C1CCCC1 +CC(C)NC(=O)CCNC(=O)NC(C(N)=O)c1ccccc1 +c1csc(CN2C3COCC2CC(OCC2CC2)C3)n1 +Cc1nnnn1-c1cccc(NC(=O)NCC(=O)NC2CC2)c1 +Cc1nn(C)c(C)c1C(=O)N(C)Cc1ccccc1F +Cc1cccn2c(=O)cc(OCC(=O)NCc3ccc(F)cc3)nc12 +Cc1ccc(N2CCC(C(=O)Nc3ccn(C)n3)C2=O)cc1C +CSc1nnc(CSc2ccc(O)cc2)s1 +CCNC(=O)N1CC2OCC(=O)N(CCOC)C2C1 +COCc1cc(-c2nc3c([nH]2)c(C(C)C)nn3C)ccc1OC +Cc1ccc(CNC(=O)c2c(C)nn(C)c2C)cc1F +CCOC(=O)C1CCCN(c2cccc(F)c2C#N)C1 +COc1cc(C(=O)Nc2nc(SC)ns2)ccc1C +Cc1nc(C)c(C(=O)OCc2cnn(C)c2)s1 +O=C(NCC(=O)N1CCc2ncccc2C1)c1ccccc1 +CC(=O)N1CCOC2CN(C(=O)Cc3ccc(F)cc3)CCC2C1 +CCCn1nc(-n2cnnc2)c(NC(=O)c2ccc(C)cc2)c1C +O=C(NCc1ccnc(-n2cccn2)c1)C1CCCC1 +C=CCCCN(C)C(=O)C1(c2ccc(F)cc2F)CCOCC1 +Cc1nn2c(-c3ccccc3Cl)nnc2s1 +N#Cc1cccc(CS(=O)(=O)N2CCCc3sccc3C2)c1 +CCOCC(=O)N1CC(S(=O)(=O)c2ccc(Cl)cc2)C1 +O=C(COc1ccc(F)cc1)N1CCN(c2ccc(F)cc2)CC1 +Cc1ccn(-c2cccc(C(=O)N3CCCC3c3cnn(C)c3)c2)n1 +CCCn1cc(C(=O)Nc2cccc(C(=O)Nc3ccccn3)c2)cn1 +CS(=O)(=O)N1CC(C(=O)Nc2nccs2)C1 +O=C(Cc1ccccc1)NCC(=O)NC1CCCCC1 +CCOC(=O)Nc1ccc(NC(=O)C2CC2)cc1OC +C=CCNC(=O)c1ccc(NC(=O)NC(C)c2ccncc2)cc1 +CNC(=O)CN(C1CC1)S(=O)(=O)c1ccc(C#N)cc1 +CCn1nc(C(=O)NCc2ccccn2)c(=O)c2cc(F)ccc21 +Cc1noc(C)c1CCC(=O)Nc1cccc2nonc12 +O=C(Nc1nc2c(s1)CN(C(=O)c1ccco1)CC2)c1ccoc1 +O=C(NC(n1cccnc1=O)C(Cl)(Cl)Cl)c1ccco1 +O=C(Oc1ccccc1F)c1cccc(-n2cccn2)n1 +Cc1ccc(CNc2cccc(OCC(N)=O)c2)s1 +C=C(C)CN(CC)C(=O)CNc1cccc(NC(C)=O)c1 +COc1ccccc1C(=O)Nc1ccc2c(c1)nc1n2CCOC1 +COc1ccc(C2=CCN(C(=O)c3cc(C)on3)CC2)cc1 +Cc1cc(=O)[nH]c(CCNC(=O)c2ccc3c(c2)nnn3C)n1 +CC1CC1c1ccc(CN2CCn3c(nnc3C(F)(F)F)C2)o1 +COc1ccc(CC(O)c2ccc3c(c2)OCCO3)cc1 +N#Cc1ccc(F)c(-c2nnc(-c3nonc3N)o2)c1 +O=C(COc1ccc(Oc2ccccc2)cc1)NCC1CCCO1 +CCCCC(O)c1cc(Cl)c2c(c1)CC(=O)N2 +O=C(NC1CCCCC1)C1CCCN1C(=O)c1cnn2ncccc12 +CC(c1ccccc1)N1CC(C(=O)N=c2[nH]nc3ccccn23)CC1=O +Cc1noc(CCCc2nc(-c3cc4ccccc4o3)no2)n1 +CN(CC1CCCC1)C(=O)Nc1ccc(Cn2ccccc2=O)cc1 +CN(CC(=O)Nc1ccc2c(c1)C(=O)NCC2)C(=O)c1ccco1 +COc1cccc(NC(=O)c2ccc(NS(C)(=O)=O)cc2)c1 +CCN(Cc1ccccc1)C(=O)Cn1c(N)nc(C)cc1=O +CSc1ccc(Cl)c(C(=O)OC(C(N)=O)c2ccccc2)c1 +CCNc1ccc(C(=O)NC(C)C(=O)NC)cn1 +CCCC(C)N(C)C(=O)c1ccc2c(c1)NC(=O)CO2 +COc1ccc(Cl)cc1C=Cc1nc(C(C)(C)NC(C)=O)no1 +CC1CCN(C(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2)CC1 +O=S(=O)(c1cc(F)ccc1F)N1CCOCC1C1CC1 +Cn1ncc2c(=O)n(CCC(=O)Nc3ccccc3F)cnc21 +COc1cncc(CC2COc3c(cccc3OC)C2)c1 +CCOc1ncccc1C(=O)N(C)C(C)c1ccccc1F +N#CC(NC(=O)c1cccc(Oc2cnccn2)c1)c1ccccc1F +N#Cc1ccc(CN2CCCN(C(=O)CCc3ccco3)CC2)cc1 +Cc1cc(SCCC(=O)Nc2nc(C)cs2)ncn1 +CS(=O)(=O)Nc1ccccc1C(=O)N1CCC(C(N)=O)CC1 +COCCN1CCCC2(CCN(C(=O)c3ccc(=O)n(C)n3)C2)C1=O +CCCC1CN(C(=O)c2ccc(Cn3nc(C)cc3C)cc2)CCO1 +N#Cc1ccc(NC2CCCN(c3ccc(C(F)(F)F)cn3)C2)nc1 +CCC(=O)c1ccc(OC(C)C(=O)Nc2cc(C)on2)cc1 +CCOc1ccc(Br)cc1NC(=O)CNC(=O)NC +CC(=O)Oc1c(Br)cccc1Br +CCc1ccccc1OCC(=O)Nc1ccc2[nH]ncc2c1 +Cc1ccc(C(C)(O)CNC(=O)Cc2n[nH]c3ccccc23)o1 +Cc1ccc(CNc2cnn(C)c(=O)c2Cl)cc1 +COC(=O)C1=C(C)Nc2ncnn2C1c1ccsc1 +CSc1ccc(C(O)CNC(=O)c2cccnc2SC)cc1 +COCCN(C(=O)c1ccc(C)[nH]c1=O)C1CCCC1 +C=Cc1ccc(Cn2c(=O)n(C)c(=O)c3sccc32)cc1 +CCOc1ccccc1NS(=O)(=O)c1ccccc1 +CCOCCOc1cccc(NC(=O)Nc2ccccc2)c1 +O=C(CC1CC1)N1CCC2C1CCC(=O)N2Cc1ccncc1 +CN(Cc1nc(-c2cccc(Cl)c2)no1)CC(O)c1ccccc1 +Cc1noc(COC(=O)c2cnn(-c3ccccc3C)c2C)n1 +COC(=O)C1=C(c2ccccc2)NC(=O)NC1c1ccc(F)cc1 +CC(=O)c1ccc(Cl)c(NCCN2CCOCC2)c1 +CCc1ccc(NC(=O)NCC(C(C)C)N2CCOCC2)cc1 +COCC(=O)Nc1ccc(NC(=O)C(C)(C)c2ccc(F)cc2)cc1 +Cc1cc(NC(=O)c2ccc(Cl)cc2)c2cc(F)ccc2n1 +O=S(=O)(Oc1cccc(Cl)c1)c1cccs1 +N#CCC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCc1noc(CC)c1CC(=O)N(CC(C)C)C1CC1 +Cc1ccsc1CNC(=O)Nc1cc(F)cc(F)c1 +Cc1nc(C)c(C(=O)NC(c2ccc(F)cc2)c2nccn2C)s1 +Nc1nc(=O)n(C2OC(CO)C(O)C2O)cc1O +Cc1cc(C(=O)Nc2ccnn2C(C)C)c(C)n1C(C)C +CC1CCCCC1OCCN1CCN(C(=O)C(C)(C)C)CC1 +CC(C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1)c1cccnc1 +COC(=O)c1cccc(S(=O)(=O)N(C)Cc2cccc(C#N)c2)c1 +Cc1cc(C(=O)N2Cc3ccccc3CC2C(N)=O)[nH]n1 +O=C(CCc1cc(F)ccc1F)NCC1CN2CCCCC2CO1 +CC(=O)NCCNC(=O)NCCc1nc2ccccc2s1 +CC(C)Cn1cc(NCc2c[nH]nc2-c2ccc(F)cc2)cn1 +CC(C)c1noc(CCNC(=O)C2CC(=O)Nc3ccccc32)n1 +O=C(CCc1ccco1)NC1CCCc2nc(-c3ccncc3)ncc21 +O=C(Nc1cccc(F)c1)c1nc2ncccn2n1 +CCOC(=O)c1cnn(-c2ccc(C(F)(F)F)cc2)c1N +Cn1cc(C(=O)N2CCCN(C(=O)c3ccccc3Cl)CC2)cn1 +CCCN(C(=O)c1cnc(N)c(Cl)c1)C1CC1 +N#CCc1cnc(CCOc2ccccc2Cl)s1 +CC1(C)OCC2(CO1)CN(C(=O)c1ccc3ncsc3c1)C2 +Cc1ccc(C(O)C(=O)Nc2ccc(Cl)cc2)c(C)c1 +COc1ccc(NC(=O)c2ccco2)cc1NC(=O)c1ccccc1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)Nc2ccc(C)cc2O)c1 +O=C(NCCCc1ccccc1)C1CCN(C(=O)NC2CC2)CC1 +Cn1c(C(=O)NCCCC(N)=O)c(Br)c2ccccc21 +COc1ccc(CN(C)C(=O)c2cccc(-c3ccoc3)c2)cc1F +COCCN(Cc1ccco1)C(=O)Nc1ccccc1N1CCCC1 +CCN(CC)C(=O)CCCNC(=O)c1ccco1 +Cc1ccc(NC(=O)Cn2cnc3ccc(Cl)cc3c2=O)c(F)c1 +O=C(NCC1CCCO1)N1CCCC1c1ccc2c(c1)OCCO2 +N#Cc1ccc(CNCCc2coc(-c3ccccc3)n2)cc1 +Cc1cc(C(=O)NC(C)c2noc(Cc3ccccc3)n2)no1 +N#CC(c1ccccc1)N1CCN(C(=O)C2CCCC2)CC1 +O=C1CC(c2nc3ccccc3[nH]2)CN1c1ccc(Cl)cc1 +Cc1csc(N(C)C(=O)COc2ccccc2C)n1 +Cc1ccoc1C(=O)Nc1nc(-c2cccs2)cs1 +CNC(=O)C(NC(=O)CSc1nncn1C(C)C)c1ccccc1 +O=C(NCC(O)c1ccc2c(c1)OCO2)c1cccnc1 +CC1Nc2cc(F)c(F)cc2N(Cc2ccccc2C#N)C1=O +COc1ccc(C2C(C(N)=O)C(C)Nc3ncnn32)cc1 +CNC(=O)c1cccc(NC(=O)CCc2nc3ncccc3[nH]2)c1 +CC(O)c1ccc2[nH]c3ccc(C(C)O)cc3c2c1 +CC=CCC(=O)Nc1ccc(OC)cc1NC(=O)C(C)C +COc1ccc(OC)c(C2NCCN(C)C2=O)c1 +CNc1cccc(NS(=O)(=O)c2ccc(OC)cc2)c1 +CCCc1ccc(CN2CCNC(C(=O)NCc3ccncc3)C2)o1 +COc1ccc(CNC(=O)c2cc3n(n2)CCCO3)cc1 +Nc1c(NCCc2ccccc2)ncnc1Nc1ccccn1 +COc1ccc(OCc2ncc(C#N)c(N)n2)cc1 +CC12CCC(C(=O)N3CCc4ccccc43)(CC1O)C2(C)C +CS(=O)(=O)c1ccc(C(=O)NCc2cccc(C(N)=O)c2)cc1 +O=C(c1ccc(-n2cncn2)cc1)N1CCCCC1Cc1ccccc1 +Cc1cc(C)c2cc(C(=O)N(C)CC(O)C3CC3)[nH]c2c1 +O=C(NCCN1CCCS1(=O)=O)c1cc(C2CC2)[nH]n1 +CNC(=O)c1cccc(NC(=O)NC(C)c2c(C)nn(C)c2C)c1 +N#Cc1nnn(-c2cccc3ccccc23)c1-c1ccco1 +COc1ccccc1-c1cc(C(F)F)n2nccc2n1 +c1nc2c3c4c(sc3nc(N3CCCC3)n2n1)CCC4 +CN(Cc1ccccc1)C(=O)Nc1cccc(S(N)(=O)=O)c1 +COc1ccc(Br)cc1-c1[nH]nc(C)c1N +COc1ccc(CN2c3ccccc3NCC2C)cc1N +CCCc1cc2c(=O)n(NC(=O)c3ccnn3CC)c(C)nc2s1 +CCc1cc(NCCCCO)n2nc(C)c(C)c2n1 +CC(C#N)Sc1nnc2c(Cl)cc(C(F)(F)F)cn12 +O=C(CS(=O)c1cccs1)N1CCOCC1 +C=CCOC(C)C(=O)Nc1ncn(CC(=O)N2CCCCCC2)n1 +COc1ccccc1-n1c(C)nc2[nH]ncc2c1=O +O=C(Nc1cc(-c2ccccn2)no1)c1cccc(C(F)(F)F)c1 +Cc1ccc(C(=O)Nc2cccc(-c3ncn(C)n3)c2)cn1 +O=c1c2ccsc2ncn1Cc1ccccc1C(F)(F)F +CCc1ccc(C(=O)Nc2c(C)cc(N)cc2CC)cc1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)c1n[nH]c2ccccc12 +Cc1noc(CSc2ncnc3ccsc23)n1 +Cn1ccnc1C(Nc1ccc2nnnn2n1)c1ccccc1 +CC(C)(C)CNC(=O)c1nccn1-c1cccc(N)c1 +COc1ccc(S(=O)(=O)NC2CCCC2)cc1F +Cc1csc(C(=O)NCc2cc(-c3ccccn3)n(C)n2)c1 +Cc1noc(CNC(=O)COc2ccc(Cl)cc2)n1 +CC(=O)Nc1ccccc1OCC(=O)Nc1cc(F)ccc1C +Nn1c(SCc2ccc(F)cc2)nnc1-c1cccnc1 +CC(=O)NC1CN(c2cnccn2)CC1c1ccc(C)o1 +N#Cc1nccnc1NCC1COC2(CCCCCC2)O1 +N#Cc1cccc(OCCN2CCN(c3ncccn3)CC2)c1 +Cc1cccc(CN2CC(F)C(OCc3nc4ccccc4o3)C2)n1 +CS(=O)c1ccc(NC(=O)NCc2ncc[nH]2)cc1 +COc1cc2c(C(C)O)nccc2c(OC)c1OC +CCC(CNCc1cc(=O)c2cc(C)ccc2[nH]1)OC +Cn1c(=O)c2c(ncn2CC(=O)Nc2cccc(F)c2)n(C)c1=O +CCC(NC(=O)N1CCOCC1C1CC1)c1cccc(Cl)c1 +COc1ccc(C(C)NS(=O)(=O)c2ccc(C)cc2C)cc1OC +CCN(CC1CCCO1)c1ccc(C#N)c(Cl)c1 +Cc1ccc(-c2ccc(C#N)c(N3CCOCC3)n2)c(C)c1 +Cc1noc(C)c1C(=O)NCc1c(F)cccc1Cl +O=C(NCc1ccco1)c1cc(-c2cccc3ccccc23)[nH]n1 +CCC(CO)NS(=O)(=O)c1ccc(C(C)(C)C)cc1 +Cc1nc(CNc2cc(Br)ccc2C)no1 +Fc1ccc(Nc2nc(N3CCOCC3)nc3nccnc23)cc1 +O=S(=O)(Nc1c(F)cccc1F)c1cccc(F)c1 +Cc1occc1-c1[nH]ncc1-c1ccnc(N2CCOCC2)n1 +Cc1ccc(NCC2Cc3ccccc3O2)c(N)c1 +Cc1cc(CC(=O)N(CCc2ccccc2)C2CCOC2)n[nH]1 +CC(C)C(NC(=O)C1CC(=O)N(C)C1)c1nc2ccccc2[nH]1 +CC(C)c1cnnn1CCCOc1cccc(N)c1 +COc1ccc(CNC(=O)c2c(F)cccc2F)c(OC)c1OC +Cc1nnc(N2CCC3(CC2)COC(COCC2CC2)C3)s1 +Cc1nscc1C(=O)N1CCN(Cc2ccccc2F)CC1 +Cc1cc(C)c(C(=O)NCCCCOc2ccc(F)cc2)c(=O)[nH]1 +Cc1cc(C)c(S(=O)(=O)Oc2cccc(CC(N)=O)c2)c(C)c1 +NC(=O)c1cccc2c1CCCN2C(=O)CCSc1ccccc1 +Cc1cc(C)n(-c2ccc(NC(=O)CSc3ccccc3)cn2)n1 +CC1CN(C(=O)c2cccc(C(F)(F)F)c2)CCO1 +O=S(=O)(NCc1cccc(Cn2cccn2)c1)c1ccccc1 +CC(C)(C)OC(=O)NCCC(=O)NC1CCOc2ccccc21 +COc1ccc(OC)c(CN(C)C(=O)c2cc(C(C)(C)C)nn2C)c1 +C=CCC(NC(=O)OC(C)(C)C)c1cccc(C)c1 +CCc1ccccc1NC(=O)COc1ccccc1C#N +CN(CCC(F)(F)F)C(=O)C1CC1c1ccccc1 +CN(C)c1ncc(CNCc2ccnc(Oc3ccccc3)c2)s1 +CN(C)C(=O)c1ccc(CN(CC(O)c2ccc(F)cc2)C2CC2)[nH]1 +Cc1cc(NC(=O)C2CC3CCC2C3)ccc1S(N)(=O)=O +COc1ccc(NC(=O)c2cc(C)nc3c2cnn3C(C)C)cc1 +N#CCn1c(C(N)c2ccccc2)nc2ccc(F)cc21 +Cc1cc(S(C)(=O)=O)ccc1NCc1noc(C2CC2)n1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1nc(C)oc1-c1ccccc1 +Cc1cc(C(=O)NC(C)Cc2cccc(Cl)c2)n(C)n1 +CCN(CC)C(=O)CCC(=O)N1CCCC1c1ccccc1OC +Cc1csc(C(C#N)C(=O)Cc2c(C)nn(C)c2C)n1 +CN(C(=O)c1ccccc1S(N)(=O)=O)C1CCCC1 +Cc1cc(COC(=O)CCc2ccc(C#N)cc2)no1 +O=C(C1CCC1)N1CCN(S(=O)(=O)c2c[nH]c3ncccc23)CC1 +CN(C)c1nc(N)nc(CSc2nc3ccc(N)cc3s2)n1 +CCSc1nnc(C(F)F)n1NC(=O)c1ccn(C(F)F)n1 +CC(C)Oc1ccc(C(=O)NCC#Cc2ccc(C(N)=O)cc2)cc1 +CCOC(C)c1noc(CSc2nccc(C(F)(F)F)n2)n1 +Fc1ccccc1CNC1(Cc2cc(-c3ccccn3)on2)COC1 +COc1cccc(NC(=O)COC(=O)c2ccc(C)cc2O)c1 +Cc1ccccc1NC(=O)C(C)Sc1ccc(N)cn1 +CCOc1cc(N)c(C(=O)OC)cc1NC(C)=O +Cc1cc(CCNC(=O)C2CCN(S(C)(=O)=O)CC2)on1 +Nc1cc(NC(=O)c2cc(Cl)ccc2F)ccc1F +CS(=O)(=O)N1CCCc2cc(C(=O)Nc3cccnc3)ccc21 +Cn1nc(C(=O)Nc2ccccc2F)cc1C(F)(F)F +CC(C)N(C)C(=O)CCCc1nc(C(C)(C)C)no1 +Cc1csc(=O)n1CC(=O)c1sccc1Br +CCCNC(=O)CNC(=O)Nc1cc(NC(C)=O)ccc1C +COc1ccccc1COC(=O)CSc1ccncc1 +Cc1cc(NC(=O)c2c(F)cccc2F)c2ncccc2c1 +CCOC(=O)N1CCN(C(C)C(=O)c2c[nH]c3ccccc23)CC1 +O=S(=O)(NC1CCCCC1Sc1ncccn1)c1ccccc1 +O=C(Nc1ccccc1)c1ccc2c(c1)S(=O)(=O)N(C1CC1)C2=O +C=CCN(CC=C)C(=O)c1cnc2ccc(C)cn12 +COc1ccc(Cl)c(NCC(=O)Nc2cccc(C(C)=O)c2)c1 +O=C(NCc1cc(F)cc(F)c1)c1ccc(F)cc1 +Cc1cc(C)n(-c2ccc(C(=O)N3CC(c4ccccn4)C3)cc2)n1 +CCc1noc(C(C)N2CCN(C3CCOC3=O)CC2)n1 +CN(C)C(=O)c1cccc(C(=O)OCC2CC=CCC2)c1 +CN(C(C)(C)C#N)S(=O)(=O)c1cccc(F)c1 +Cc1cc(C)n(-c2ccc(NC(=O)N3CCCC(C)C3)cn2)n1 +CCc1c(C)sc(NC(=O)OC)c1C(=O)N1CCOCC1 +CN(C)C(=O)N1CC2CN(c3ncccn3)CC2C1 +Cc1cc(C)nc(NC(=O)c2cnc(C(C)(C)C)nc2N)n1 +Cc1ccc(CNC(=O)C(Cc2ccccc2)NC(N)=O)s1 +Cc1nc(SCC(=O)NCc2ccco2)oc1C +Cc1ccsc1C(=O)N1CCN(C(=O)Nc2ccc(F)cc2)CC1 +CC(=O)c1ccc(N2CCN(CC(=O)N(C)C(C)(C)C#N)CC2)cc1 +Cc1n[nH]c(-c2ccc(-n3ccnc3-c3cccc(F)c3F)cc2)n1 +O=C(Nc1ccc(S(=O)(=O)NC2CCCCC2)cc1)c1ccco1 +NC(=O)C1CCCN(C(=O)Nc2ccc(Cl)cc2)C1 +CC(NC(=O)N(Cc1cccc(O)c1)CC1CC1)c1nncn1C +O=C(NCc1ncc(-c2ccccc2)o1)c1c(O)cc(F)cc1F +CCc1nc2n(n1)CCCC2NC(=O)NCc1ccc(F)cc1 +COC(=O)C(NC(C)=O)C12CC3CC(CC(C3)C1)C2 +CC(C)Nc1ncnc2c1nnn2Cc1ccccc1Cl +CCCn1ccnc1-c1cccc(NC(=O)c2ccc3nncn3c2)c1 +COC(=O)c1cccc(NC(=O)c2ccc3[nH]cnc3c2)c1O +Nc1nc(SCC(=O)Nc2ncc(Cc3ccccc3)s2)n[nH]1 +CCCS(=O)(=O)N1CCCC1C(=O)NC1CCCCC1 +COc1ccnc2c1ccn2S(=O)(=O)c1ccc(C)cc1 +COCC(C)NC(=O)COc1ccc(F)cc1Br +COc1cc2c(cc1OC)CN(C(=O)NCC1CC1)CC2 +CC1CCCCC1NC(=O)c1nn(C)cc1Br +CCN1C(=O)CCC12CCCN(c1nccc(C(F)(F)F)n1)C2 +CCOc1ccccc1-n1c(Cc2c(C)noc2C)n[nH]c1=O +CS(=O)(=O)NC1CCN(c2nccc(C(F)(F)F)n2)CC1 +CC1Oc2ccccc2N(Cc2nc(-c3ccccc3)no2)C1=O +CC1CCCCN1C(=O)CCCNC(=O)c1cccs1 +Cn1ccc(C(=O)NCCCn2nc(C(F)(F)F)cc2C2CC2)n1 +COCCCCC(=O)N1CCCCCC1c1ccco1 +CNC(=O)c1c(NC(=O)c2ccco2)sc2c1CCCCC2 +O=C(CCN1CCOC(C2CCCO2)C1)N1CCOCC1 +Cc1ccccc1-c1cnnc(NCC2COCCO2)n1 +Cc1ccc(-c2noc(CN3CCN(C(=O)CC(C)C)CC3)n2)cc1 +CC(=O)Nc1ccc(SCC(=O)Nc2ccc(C)cc2C)cc1 +Cc1cc2nnc(SCC(=O)NCc3ccccc3)n2c(N)n1 +N#CC1(NC(=O)CNc2ccccc2C(F)(F)F)CCCC1 +O=C(NCc1ccc2c(c1)OCO2)c1nnc(-c2ccccc2)o1 +CCc1cccc(C)c1NC(=O)Cn1cnc2cc(C)c(C)cc21 +COc1ccc(-c2nnc(SCc3ccon3)n2N)cc1OC +CN(Cc1ccc(O)cc1)C(=O)CNC(=O)c1ccc(F)c(F)c1 +CCNC(=O)c1nnn(-c2ccc(OCC)cc2)c1-c1cccnc1 +O=C1C(=O)N(Cc2ccc(F)cc2Cl)c2ccccc21 +COc1ccc(CN(C)C(=O)COc2cccc3c2CCC3=O)cc1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(OC(F)F)c(OC)c1 +O=C1CCc2cc(C(=O)N3CCN(c4nccs4)CC3)ccc2N1 +CC(NC(=O)C1CC1(Cl)Cl)c1nc2ccccc2[nH]1 +COC(=O)CSc1sc(=O)sc1SC +CC(C)(C)c1cnc(CNC(=O)Cc2cccc(OCC#N)c2)o1 +O=C(c1nc(-c2ccccn2)no1)N1CCN(c2ccccc2)CC1 +CC(C(=O)NCc1ccccc1F)n1nnc(-c2ccccc2)n1 +CCc1nc(-c2cn(Cc3ccc(C)cc3)nn2)no1 +Cc1cc(=O)c(O)c(CN2CCOCC2)n1CCOCCO +O=C(c1ccccc1)N1CCN(c2n[nH]cc2-c2ccncc2)CC1 +Cc1nc2ccccn2c1C(=O)Nc1cccc(Cl)c1 +N#CCCCOc1cccc(NC(=O)CNC(N)=O)c1 +Cc1oc(-c2ccccc2)nc1CC(=O)NCCc1ccco1 +Cc1ccc2c(c1)[nH]c(=O)c1c(C(=O)NCc3cccnc3)nnn12 +CCC(=O)Nc1ccc(NC(=O)c2ccccc2)c(C)c1 +O=C(COC(=O)Cn1ccc(=O)[nH]c1=O)Nc1ccc(Cl)cn1 +Cc1ccc(C(=O)c2ccc(OCC(N)=O)cc2)cc1C +CCOC(=O)c1ccc(N2CCCC(N3CCNC3=O)C2)nc1 +Cc1ccccc1COC1CCN(C(=O)c2cccn2C(C)C)CC1 +Cc1cc(C(=O)Nc2c[nH]ccc2=O)ccc1-n1cncn1 +Cc1cc(C)n2nc(CC(=O)Nc3oc(C)c(C)c3C#N)nc2n1 +CCCCCNC(=O)c1c(N)n(N)c2nc3ccccc3nc12 +O=C(C1CC12CCOCC2)N1CCC(OCc2ccccc2F)CC1 +O=C(Nc1ccc(F)cc1)c1nn(-c2ccc(F)cc2)ccc1=O +O=C(NCCc1ccc(Cl)cc1Cl)Nc1cn[nH]c1 +O=C(NCCCc1ccccc1)c1nnn(-c2ccc(Cl)cc2)n1 +C=CCn1c(SCCCC)nc2c1c(=O)[nH]c(=O)n2C +O=C(NCc1cccc(COCc2ccccc2)c1)Nc1ccccn1 +CC1CCCCC1NC(=O)CN1CCN(c2ccccc2O)CC1 +Cc1ccccc1NC(=O)CSc1nncn1C1CC1 +COc1ncnc2c1CCN(C(=O)c1cnccn1)CC2 +NC(=O)CCCNC(=O)c1cc2ccccc2nc1N1CCCC1 +CS(=O)(=O)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1 +CC(C)Oc1ccc(S(=O)(=O)N(C)C(C#N)C(C)C)cc1 +O=C(NCCc1cccc(F)c1)c1n[nH]c(=O)c2ccccc12 +CC1(C)C(=O)NCCN1C(=O)c1ccc2ncsc2c1 +Cn1cc2ccc(F)c(C(=O)Nc3ccccc3)c2n1 +CC(=O)Nc1ccc(Nc2nc(=O)[nH]nc2C)cc1 +COc1ccc(F)cc1C(=O)NCc1ccccc1CO +CCn1nc(C)c(CNC(=O)c2nc(-c3ccncc3)no2)c1C +O=C(Nc1ccc(OCC2CC2)cc1)c1ccc2ncnn2c1 +COC(=O)N(C)CC(=O)Nc1ccc(C)cc1OC +CC(C1CC1)N(C(=O)CN1C(=O)CSc2ccccc21)C1CC1 +CCC(NC(=O)N1CCOCC1CC)c1ccncc1 +O=C(c1ccc(-n2cncn2)c(F)c1)N1CCOc2ccc(F)cc21 +O=C(Nc1ccncc1F)NC1CCc2[nH]ncc2C1 +Nc1c(C(=O)c2c[nH]c3ccccc23)cnn1-c1ccccc1 +CC(=O)N1CCN(c2ccc(Cl)cc2N)CC1 +NC(=O)c1cccc2c1CCCN2C(=O)C1CCCO1 +CCc1onc(C)c1NC(=O)c1ccc(-c2cscn2)cc1 +COc1ccc(OC)c(COC(=O)C2COc3ccccc32)c1 +Cc1nc(CN2C(=O)CCC3C2CCN3C(=O)NC2CC2)cs1 +O=C(c1ccncc1)N1CCN(c2ccnc(-c3ccccc3)n2)CC1 +COCCNc1ccc(CNC(=O)Nc2ccc(C)cc2)cc1 +CCCn1nc(C(=O)N(C)c2ccc3ccccc3c2)ccc1=O +Cn1cccc(NC(=O)CCSc2ccccc2Cl)c1=O +Cc1csc2nnc(-c3nnc(NCC(C)C)s3)n12 +CCC1CN(C(=O)c2cc(C)n(CC)c2C)CC1N1CCOCC1 +COCCN(C(C)=O)c1nc(CSc2ccc(C)cc2)cs1 +O=C(Nc1cc(F)cc(F)c1)c1ccc(-n2ccnn2)cc1 +OCc1cccc(Oc2ccnc(C(F)(F)F)n2)c1 +Cc1n[nH]c(-c2ccc(C(=O)N(C)C3CCC(C)(C)CC3)cc2)n1 +CC(=O)Nc1ccc(-c2ccc3nnc(C)n3n2)cc1 +COC(=O)CC1CN(Cc2ccc(-n3ccnc3)cc2)CCO1 +CC(Oc1ccc(C#N)cc1)C(=O)Oc1ccccc1 +CC1CCN(C(=O)Cn2nnnc2-c2ccc(Cl)cc2)CC1 +CCc1ccccc1NC(=O)Cn1nc(C)c2ccccc2c1=O +CCn1ncc(C(=O)N(Cc2cccnc2)Cc2cccnc2)c1C +Cn1c(=O)c2nc(-c3ccccc3O)[nH]c2n(C)c1=O +O=C(NCc1ccc(CNC(=O)c2ccco2)cc1)c1ccco1 +CS(=O)(=O)c1ccc(-c2cccc(OCC(N)=O)c2)cc1 +O=C(CCNC(=O)c1ccnc2c1OCO2)NCc1cccc(F)c1 +NC(Cc1c[nH]c2ccccc12)C(=O)OCc1ccccc1 +CN(CC1CCOC1)C(=O)c1ccc(-n2ccnn2)cc1 +CC(CNC(=O)c1ccon1)c1nc(-c2ccccc2)no1 +COc1cc(C(=O)NCc2cc3ccccn3n2)cc(OC)c1OC +Cc1cccc(C(=O)N(Cc2ccsc2)Cc2ccco2)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)Nc1cn(C)c(=O)cc1C +COC(=O)c1ccccc1S(=O)(=O)NCCO +Cc1nc(COc2ccccc2C(=O)NCCc2cnn(C)c2)no1 +CCN(CCO)C(=O)c1cc(Br)ccc1O +O=C(NCc1cccc(O)c1)c1cccc2[nH]ccc12 +CC(NC(=O)c1cc2ccccc2oc1=O)C(=O)N1CCOCC1 +CCC(=O)NCc1cc(Cl)cc2c1OCOC2 +CCC(C#N)Oc1cccc(CNC(=O)NC2CCCCC2O)c1 +CC(=O)c1ccc2c(c1)N(CC(=O)N(C)Cc1ccccc1)CCO2 +O=C1CN(C(=O)C2C3CCC4(CC(=O)c5ccccc5O4)C32)CCN1 +CCCc1nc(Cn2c(-c3ccccc3C)noc2=O)no1 +O=C(c1ccc2ncsc2c1)N1CC(c2nc3ccccc3[nH]2)C1 +COc1ccc(C)cc1NS(=O)(=O)c1cc(-c2ccno2)oc1C +CCCNC(=O)c1ccccc1NC(=O)c1c(OC)cccc1OC +Cc1cc(NC(=O)c2cc(C3CC3)nc3ccccc23)n(C)n1 +COc1ccc(OCCC(=O)Nc2ccc(-n3ccnc3)cc2)cc1 +COc1cccc(NC(=O)N2CCCC2c2nc(C3CC3)no2)c1 +CCCCNC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1 +NC(=O)N1CCCC(C(=O)Nc2cccc(NC(=O)C3CC3)c2)C1 +NC(=O)c1nnn(-c2cccc(F)c2)c1-c1ccc2c(c1)OCO2 +CCN(CC)C(=O)CNC(=O)c1ccc(Cl)c(Cl)c1 +CSc1cccc(NC(=O)N2CCNC(=O)C2)c1 +CC(C)(O)CN1CCOC(c2ccc(Cl)cc2)C1 +O=C1CN(CCOc2ccc(Cl)cc2)CCN1 +COc1ccc(C(=O)N2CCN(c3ccccn3)CC2)cc1OC +O=C(NCc1cscn1)NCc1coc(-c2cccs2)n1 +CCCCc1nnc(NC(=O)Cn2c(=O)oc3ccccc32)s1 +CCOCCNC(=O)C1CC1c1ccccc1C(F)(F)F +O=C(Cc1cccs1)NCC1(c2ccccc2)CCOCC1 +COc1cccc(NC(=O)COc2cccc3cccnc23)c1 +Cc1nccn1-c1ccc(NC(=O)Cn2ccc3ccccc32)cn1 +Cc1ccc(OC(C)C(=O)N2Cc3ccccc3CC2C(N)=O)cc1 +Cc1noc(C)c1CN(C)C(=O)Nc1ccccc1OCC1CC1 +Cc1ccc(C)c(C(=O)OCC(=O)NCc2cccs2)c1 +CNC(=O)NCC1(c2cccc(F)c2)CCOCC1 +COc1ccc(F)cc1C(=O)CCCC(=O)NC1CCCC1 +CCCCCNC(=O)c1[nH]c(C)c(C(C)=O)c1C +CCOc1ccc(-c2c[nH]c(-c3ncnn3CC)n2)cc1 +Cn1c(=O)[nH]c2cc(-c3noc(CNC(=O)c4ccccc4)n3)ccc21 +COc1cccc(C(=O)N(C)C(C)c2ccc(S(C)(=O)=O)cc2)c1 +Cc1nonc1NC(=O)c1cc2cc(C(F)(F)F)ccc2n1C +COc1cccc(C(=O)NC2CCC3(CC2)OCCO3)c1F +Cc1ccccc1OS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CC(C)N(Cc1ccccc1)C(=O)c1cnc2snnc2c1 +COc1ccc(C(O)CNc2ccccc2)c(OC)c1 +COCCCNC(=O)c1nc2ccccn2c1-c1ccc(C)cc1 +CC(=O)c1ccc(OCC(=O)c2cccs2)cc1 +NS(=O)(=O)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 +CC1CCN(C(=O)c2ccc(NC(=O)C3CC3C)cc2)C(C)C1 +Cc1nnc2n1CCN(C(=O)C1(c3ccc(F)cc3)CCCC1)C2 +O=C(NCCc1ccccn1)C1COC(=O)N1Cc1cccs1 +COc1ccc(NC(=O)C2CC(=O)N(C3CCOCC3)C2)cc1 +CC(=O)Nc1cc(NC(=O)c2ccc(C)[nH]c2=O)ccc1F +CC(C)Oc1ccc(F)cc1NC(=O)NCc1ccncc1 +Cc1cc(C2Nc3ccccc3C(=O)N2C)cc(C)c1O +COc1cccc(C(N)c2nc(-c3ccccn3)n[nH]2)c1 +CCOc1ccc(C(=O)CNc2cccc(C#N)c2)cc1 +CCCCOc1ccc2cc(C(=O)N3CCNC(=O)CC3)[nH]c2c1 +CC1CN(C(=O)NCc2ccc(OC3CCCC3)nc2)CC(C)O1 +CN(C(=O)C1COc2ccccc21)C1CCc2ccccc2C1 +Cc1ccc(C)c(NC(=O)c2cnc3ccccn3c2=O)c1 +O=C(NCC(=O)N1CCCC(O)C1)NC1CCCCC1 +CN(C(=O)c1cncc2ccccc12)c1cccc2ncccc12 +O=C(NCCn1ncc2ccccc2c1=O)c1ccc(Cl)cc1 +COc1ccc(Cc2nc3ccc(N)cn3c2CC#N)cc1 +COc1ccc(-c2cc(C(=O)N3CCCCC3)no2)cc1OC +CCc1onc(C)c1NC(=O)CCCNC(=O)OC +CCCSc1nnc(COc2cccc(C)c2)o1 +C=CCNC(=O)C(C)Oc1ccccc1C(O)CC +Clc1ccc(-c2nccn2CCc2c[nH]cn2)cc1 +O=C(NCCc1ccco1)c1nn2ccccc2c1Cl +COc1ccccc1C#CCNC(=O)c1ccsc1 +C=C(C)CN1C(=O)C(=O)c2cc(Br)ccc21 +COc1ccc(SCc2ccc(C(=O)N(C)C)cc2)cc1 +COCC(=O)Nc1nc2ccc(OCC(F)(F)F)cc2s1 +COCCNC(=O)c1cccc(N2C(=O)CCS2(=O)=O)c1 +Cc1ccc(C(=O)NCc2cccc(N3CCCC3=O)c2)c(=O)[nH]1 +NC(=O)c1cccc(COC(=O)CCc2nc3ccccc3s2)c1 +Cc1nc(SCCO)c2c(C)c(C)sc2n1 +O=C(Nc1cc(F)ccc1O)c1cccc(OCC(F)F)n1 +Nc1ccc(Cl)cc1NC(=O)CSc1ccccc1 +O=S(=O)(NCc1ccccn1)c1cc(F)cc(F)c1 +Fc1ccc(-c2nn3c(-c4ccncc4)nnc3s2)cc1F +Cc1ocnc1CNC(=O)Nc1ncc(-c2ccccc2)s1 +CC(C)COC(C)c1noc(Cn2ncc(Cl)c(Cl)c2=O)n1 +O=C(CC1CCCC1)NCCn1nc2ccccn2c1=O +Cc1nc2nc(C)c3c(=O)n(CCC4CCC(O)CC4)ccc3n2n1 +COc1cc(C)c(CNc2ccccc2-n2ccc(C)n2)cc1OC +CC(C(=O)NCc1ccccc1F)N1CCN(C(=O)C2CC2)CC1 +O=C(N1CCCC1)C1(c2cc(-c3ccccc3F)on2)CC1 +CC(OC(=O)CSc1nnnn1C1CC1)C1CCCCC1 +CCCCOc1ccccc1NC(=O)N(C)Cc1ccccn1 +O=C(Cc1cccc(F)c1F)N(CC1CCCO1)C1CCCC1 +N#Cc1ccc(Cl)c(NC(=O)c2ccc(F)cc2F)c1 +CCCC(C)C(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1 +O=C(Nc1ccc2c(c1)OCCO2)c1ccc2nonc2c1 +Cc1ccc(C(O)c2cc3[nH]c(=O)[nH]c3cc2C)cc1 +CC(C)(C)OC(=O)N1CCCC(c2ccc(N)cc2)C1 +CC(C)(C)NC(=O)CNC(=O)c1ccc(Cl)c(Cl)c1 +Cc1oc2ccc(O)cc2c1C(O)c1ccccc1 +COc1cc(NCC(C)C)nc(C2CCCO2)n1 +O=C(NCCCn1ccnc1)c1cnn2cccnc12 +Cc1ccc(-c2cc(C(=O)NCc3ccncc3)n[nH]2)c(O)c1C +Cc1ccc(NC(=O)N(CCO)C2CCCC2)cc1 +CC(C)(C)CC(=O)N1CCN(Cc2noc(-c3ccccc3)n2)CC1 +COC(=O)CCNC(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +COCCOc1ncccc1NC(=O)Cc1ccccc1O +O=C(NCC1COCCO1)Nc1ccc(Cl)cc1 +COc1ccc(NC(=O)C2CC(=O)OC23CCCC3)cc1 +O=C(NCCc1nc2c(s1)CCCC2)C1Cc2ccccc2O1 +CN(C)C(=O)CN(C)C(=O)c1c[nH]c2ccccc12 +Cc1n[nH]cc1CNC(=O)c1ccc(OCC(N)=O)cc1 +Cc1cc(C(C)NC(=O)C2CC(=O)N(CC(C)C)C2)c(C)s1 +N#CC(C1CCCCC1)N1CCN(C(=O)Cn2ccccc2=O)CC1 +CCN(CCC#N)C(=O)CSc1ccc(F)cc1 +N#CCCN(C(=O)c1cccc(Cl)c1)c1ccccc1 +COCCN(Cc1cccnc1)C(=O)c1ccncc1F +Cc1ccc(C(O)C(=O)N(C)CCc2ccncc2)cc1 +COc1cc(C)c(NC(=O)Cc2ccc(F)cc2F)cc1OC +O=C(Cc1nc2ncccn2n1)N(Cc1ccccc1)c1ccccc1 +O=C(Nc1cc(F)ccc1F)Nc1c[nH]c(=O)[nH]c1=O +N#Cc1ccc(CN2CCc3c(Br)cccc3C2)o1 +O=C(CNc1ccccc1-n1cccn1)Nc1ccccc1F +COc1ccc2c(C(=O)Nc3nc(C)cs3)cc(=O)oc2c1 +COCCN1C(=O)CCC2C1CCN2Cc1nccs1 +Cc1noc(C)c1CNc1cccc(C(=O)NCC(F)(F)F)c1 +CCOc1ccc(-c2nc(-c3cccc(N)c3)cc(=O)[nH]2)cc1 +Cc1ccccc1C1CCCN1C(=O)c1ccn(C)n1 +Cc1occc1C(=O)N1CC2CN(S(C)(=O)=O)CCOC2C1 +CN(Cc1cnccn1)C(=O)Nc1cccc(N2CCCCCC2)c1 +CC(C)CN(C(=O)NCc1ccnn1C)C1CC1 +COCCNC(=O)CN1CCN(C(=O)c2cc(C)sc2C)CC1 +COc1ccc(S(N)(=O)=O)cc1C(=O)Nc1cccc(C)c1C +COc1ccncc1NC(=O)c1cccc(COc2ccc(C)nc2)c1 +Cc1nnc(SCC(=O)c2sccc2Br)o1 +COCCNC(=O)Cc1ccc(NC(=O)c2ccc(C)cc2)cc1 +CC(C)c1ncc(Cl)c(C(=O)N2CCCCC2Cn2cccn2)n1 +Cc1nc(SCc2nc(C(C)C)no2)c2c3c(sc2n1)CCC3 +Cc1cccc(NC(=O)C(C)Sc2nccc(=O)[nH]2)c1C +O=S(=O)(N=c1cccc(CO)[nH]1)c1ccccc1Cl +Cc1cccc(OCCC(=O)NCC2(C(N)=O)CCOCC2)c1C +O=C(NC(CN1CCOCC1)c1ccccc1)C1CC1c1ccco1 +Cc1cnc(CCNC(=O)C(C)Oc2ccc(Cl)cc2C)s1 +CC(C)CNC(=O)c1onc(-c2ccccc2F)c1N +O=C(NCCOc1ccc2ccccc2c1)NCc1cccnc1 +COCCNC(=O)C1CN(C(=O)COc2ccccc2F)C1 +CCC(C)Oc1ccc(NC(=O)c2cc(NC(C)=O)ccc2F)cc1 +CCC1CN(C(=O)CCc2nc(-c3cccs3)no2)CCO1 +CN(Cc1ccccc1)C(=O)Nc1ccc2c(c1)OCC(=O)N2 +O=C(Cn1ccc2ccccc21)NCc1ccco1 +Cc1ccc(CC(=O)Nc2sccc2C#N)c(C)c1 +Cc1cc(C)c(OCCN2CCC(=O)CC2)cc1C +COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccccc1C(C)=O +Cc1c(NC(=O)CNC(=O)OC(C)(C)C)cccc1OC(F)F +N#CCCN1CCN(C(=O)c2cccc(OCc3ccccc3)c2)CC1 +CSc1n[nH]c2ncnc(NCCc3cccc(Cl)c3)c12 +O=C(NCCNc1cnccn1)C1CC(=O)N(Cc2ccco2)C1 +Cc1ccc(C(=O)NCCOc2ccc(C(F)(F)F)cn2)cn1 +O=C(CCC(=O)c1cccs1)OCc1ccc(F)cc1 +COC(=O)c1ccc(NCc2ccc(C#N)cc2)nc1 +CC(C)NC(=O)c1ccccc1NC(=O)c1c[nH]c2cccc(F)c12 +CC(=O)N(CCc1ccccc1)CC(=O)N1CCCC1C1CCC1 +CCC(CCO)NC(=O)Nc1ccc(Oc2ncccn2)cc1 +Cc1oc(-c2cccs2)nc1CC(=O)N1CCOC2CCCC21 +CC1CCN(S(=O)(=O)c2ccc3c(c2)NCC(C)O3)CC1 +Cc1ccncc1NCc1ccc(OC(F)F)cc1 +O=C(NCCn1ncc2c(=O)n(Cc3ccccc3)cnc21)C1CC1 +CSc1nc2scc(-c3ccccc3)c2c(=O)n1C +CC(C)(CC(=O)N1CCC(C(N)=O)c2ccccc21)c1ccccc1 +CCOC(=O)CN(CC)S(=O)(=O)c1ccc(C)s1 +O=C1NC(c2ccccc2)C(=O)NC1c1ccccc1 +CCc1nc(Cn2cnc3c(Cl)cc(Cl)cc3c2=O)no1 +CNC(=O)c1cnc(C)nc1CCNC(=O)COc1ccc(F)cc1 +Fc1ccc2[nH]nc(-c3cnn(Cc4ccccc4)c3)c2c1 +COc1cccc(NS(=O)(=O)c2ccc(C)cc2)c1 +CC1CN(CC(=O)NCCCN(C)c2ccccc2)C(C)CO1 +CSc1nsc(NC(=O)CCC(=O)c2ccccc2)n1 +CC(C)c1nnc(NC(=O)C2(c3ccccc3)CC2)s1 +Cc1ccc(-c2nnc(-c3nonc3N)o2)c(F)c1 +Cc1cccc(NC(=O)Cn2nnc3ccccc32)c1 +CCc1ccc(NC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1 +Cc1ccn2c(=NC(=O)c3cnc4c(cnn4CC(C)C)c3)[nH]nc2c1 +COC(=O)C1(NC(=O)C(C)OCc2ccccc2)CCCCC1 +O=C(c1ccc(-c2ccccc2)o1)N1CCc2ncccc2C1 +CC(C#N)CCC(=O)N1CCN(c2ccc(F)cc2)CC1 +Cc1cccc(C(CC(=O)NCc2ccoc2)NC(N)=O)c1 +CC(=O)c1ncnn1CC(=O)c1ccc(Cl)cc1Cl +Cc1nc2cc(-c3ccc(F)c(F)c3)ccc2c(=O)[nH]1 +CC(c1ccccn1)N(C)C(=O)Nc1ccc(Cn2cccn2)cc1 +Cc1ccccc1-c1nnn(Cc2cc(=O)n3ccccc3n2)n1 +CN(C)C(=O)C1CCCN1c1nc(N(C)C)cc(C(F)(F)F)n1 +Cc1ccccc1OCC(=O)NCCc1nc2ccccc2[nH]1 +Cn1cc(C(=O)Nc2ccc(OCc3ccccn3)cc2)cn1 +CC(=O)c1sc(C(C(C)C)N2CCOCC2)nc1C +Cc1ccc(NC(=O)N(CCC#N)Cc2cccnc2)cc1 +CN1CC(C(=O)N(C)CCCc2ccccc2)CC1=O +O=C(COC(=O)c1ccccc1F)NCCc1ccc(Cl)cc1 +Cn1c(CO)cnc1SCCCNC(=O)C1CCCC1 +Cc1cc(C(=O)Nc2nc3c(s2)COCC3)c(C)o1 +CC(CC#N)N(C)C(=O)c1ccc(C(C)(C)C)cc1 +O=C1NCCCCC1Sc1nnc(N2CCCCC2)n1C1CC1 +CCCC(=O)Nc1cccc(NC(=O)c2cccc(N(C)C)c2)c1 +Cc1occc1C(=O)NCCNc1ncccc1C(F)(F)F +Cc1cccn2c(NC(=O)c3cccnc3)c(-c3ccccc3)nc12 +COc1ccc(NC(=O)c2cc(NC(C)=O)cc(NC(C)=O)c2)cc1 +CCNC(=O)N1CCC(C(=O)NCCCOC(C)C)CC1 +Cn1cccc(NC(=O)C(O)c2cc(Cl)cc(Cl)c2)c1=O +O=C(NCc1cccs1)c1cn2cccnc2n1 +CCN(Cc1cnn(C)c1)C(=O)NCc1cccnc1 +N#Cc1cccc(C(=O)Oc2cccc(N3CCCC3=O)c2)c1 +CC(C)Cn1ncc(C(=O)OCC2CCC(=O)N2)c1C1CC1 +COc1cccc(CS(=O)(=O)c2cccc(C)c2)c1 +COCCNc1nnc(SCc2cn3cccc(C)c3n2)s1 +Cc1occc1C(=O)Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 +COc1cc(CO)ccc1OCCc1ccc2c(c1)OCO2 +COc1ccc(NC(=O)N(C)Cc2ccccc2)cc1 +CC(C)CCC(=O)N1CCN(CC(C#N)CCC#N)CC1 +Cc1cc(Cl)ccc1OCCCC(=O)NC1CC1 +C#CCN1CCC(C(=O)N(CCc2cccc(F)c2)C2CC2)CC1 +COc1ncccc1CNC(=O)NCCc1ccc2c(c1)OCCO2 +Cc1cccn2c(=O)c(C(=O)N3CCC(C)CC3)cnc12 +CCCNC(=O)c1cccc(NCc2cccc(OC)c2)c1 +CCCOc1ccc(-c2cnc(SCC(N)=O)nc2N)cc1 +Nc1cc(C(=O)NC2CCCCCC2)ccc1F +COC(=O)CCCN(C)C(=O)c1cc(F)ccc1N +Cc1ccc(CNC(=O)Nc2cccc(-n3nnnc3C)c2)c(C)c1 +Cn1nnnc1NCc1cccc(Cl)c1Cl +NC(=O)COc1cccc(COC(=O)c2cnns2)c1 +CCc1ncc(C(=O)NC(C)C(=O)N2CCCC2)s1 +Cn1nnc2c1C(COCc1ccccn1)CN(Cc1ccco1)C2 +Cc1cc(NC(=O)c2cccc(-c3ccoc3)c2)sn1 +CCC(C)(C)C(=O)N1CCC(OCc2ccc(F)cc2)CC1 +CC1=CCC2CN(C(=O)CCn3cnc4ccccc43)CC2C1 +CCCNC(=O)c1cccc(C(=O)NCC(C)C)c1 +O=C(CCSc1ccc(F)cc1)Nc1ccc2c(c1)OCC(=O)N2 +Cc1n[nH]c2ncc(NC(=O)c3ccccc3C#N)cc12 +NC(=O)c1ccccc1OCC(=O)N1CCOCC1 +CN1C(=O)CN(C(=O)c2ccccc2)C1C(C)(C)C +Cc1cccc(OC(=O)Cc2ccc3c(c2)OCCO3)c1 +O=C(c1cnccn1)N1CCNC(c2ccccc2)C1 +CC(C)CC(NC(=O)C1COc2ccccc2C1)C(=O)N(C)C +CCC(C(=O)OC)N1C(=O)COc2ccc(C(C)=O)cc21 +CN(CCC#N)C(=O)Nc1ccc(COC2CCCC2)cc1 +COC(=O)C(C)n1c(C)nc2cc(OC)c(OC)cc21 +CCNC(=O)c1ccc(C)c(NC(=O)c2ccc(OC)cc2OC)c1 +Cc1ccc(S(=O)(=O)Nc2ccc(F)c(N)c2)cc1C +O=C(CCn1cnnn1)N1CC2CCC1CN(c1cnccn1)C2 +CN(Cc1ncnn1C)c1nccc(OCc2ccccc2)n1 +CCS(=O)(=O)N1CCC2(CC1)CN(c1ncccn1)CCO2 +CNS(=O)(=O)C1CCN(C(=O)CCCc2cc(F)ccc2F)C1 +Cc1cnc(CNC(=O)CCc2n[nH]c3c2CCCC3)cn1 +O=C(CC1CCCCC1)NCCNC(=O)N1CCC(CO)CC1 +COc1ccc2c(=O)c(Oc3cnn(-c4ccccc4)c3)coc2c1 +CC(C(=O)NCCNC(=O)Cc1cccc(F)c1)c1cccs1 +CN(Cc1cnccn1)c1cc(-c2ccccc2F)nc2ccnn12 +O=C(NCc1ccc(F)cc1F)c1ccccc1-c1nc[nH]n1 +FC(F)(F)CN(Cc1nc(C(F)(F)F)cs1)CC1CC1 +CC(C)C(NC(=O)C1CC1C)c1nc2ccccc2[nH]1 +CN(Cc1ccccc1F)C(=O)CNc1ccc(-n2cncn2)cc1 +Cc1cccc2c1CNCC2NC(=O)c1ccccc1 +N#Cc1ccc(OC(F)F)c(NC(=O)c2cc(F)cc(F)c2)c1 +CC(=O)Nc1ccc(SCc2nc(-c3cccs3)no2)cc1 +COc1ccc(C)cc1-n1cc(C)c(C)c(C#N)c1=O +O=C(Nc1ccc(OC(F)F)c(Cl)c1)C1CC(=O)N(C2CC2)C1 +O=C(c1ccccc1F)c1cccc2cccnc12 +CCC(C)N1C(=O)c2ccccc2NC1c1ccco1 +CCc1nnc(CN2CCN(CC(O)c3ccccc3)CC2)o1 +Cc1ncsc1-c1nc(-c2ccc(N)cc2)no1 +O=C(Nc1ccc(C(=O)N2CCOCC2)cc1)C1CC2C=CC1C2 +O=C(CCc1cccnc1)NCc1ccc(F)cc1 +CCCCCCN1CC2(CCN(C(=O)c3cccnn3)CC2)OC1=O +COc1nc(C)ccc1-c1noc(-c2ccccc2C)n1 +Nc1cccc(-c2n[nH]c(-c3ccc(F)c(F)c3F)n2)c1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1ccc2ccccc2c1 +Cc1nc(CC(=O)NCC(=O)NC(C)(C)C)cs1 +CCC(C(=O)Nc1ccccc1Cl)n1cnc2ccccc2c1=O +O=C(CCC(=O)c1ccc(F)cc1)Nc1ccccc1F +Cc1ccc(NC(=O)NC(CO)CC(C)(C)C)cc1S(C)(=O)=O +CCn1cc(C(=O)NCc2c(F)cccc2OC(F)F)cn1 +O=C(c1cccc(-n2cnnn2)c1)N1CCc2ccccc21 +CC1CN(CC(=O)Nc2cc(Cl)ccc2-n2cncn2)C(C)CO1 +CS(=O)(=O)c1cccc(C(=O)Nc2cccc(Cl)c2)c1 +CCc1nc(CC(=O)N(C)C(C)c2ccccc2)cs1 +CC(C)(C)C(=O)NCCCC(=O)NCc1cscn1 +O=S(=O)(C1CC1)N1CCCn2c(nnc2Cn2cccc2)C1 +CC(C)CNC(=O)NCc1ccc(NC(=O)NC(C)C)cc1 +c1nc(Nc2ccc(-n3cnnn3)cc2)c2c3c(sc2n1)CCCC3 +Cc1cnc(C(=O)N(CCc2ccccc2)Cc2cccs2)cn1 +Cc1ccc(C(CNC(=O)Cc2c(C)noc2C)N2CCOCC2)o1 +CSc1nnc(Cn2cnc3sc4c(c3c2=O)CCC4)o1 +CCCN(CC(F)F)C(=O)NCc1cn(-c2ccccc2)nn1 +O=c1c2cnc3c(Cl)cccc3c2nc2sccn12 +C=CCNC(=O)c1ccc(NC(=O)c2cc(C)sc2C)cc1 +CC(CC#N)C(=O)c1ccc(Br)cc1 +Cc1ccccc1N1CCC(C(=O)NCC(C)C)C1=O +CCc1nn2cc(-c3cc(C)ccc3C)nc2s1 +CCCCN(C)S(=O)(=O)c1cc(Br)ccc1OC +COc1ccc(NC(=O)c2sc(NC(=O)C3CC3)nc2C)cc1 +Cc1ccc(CC(=O)N2CCN(Cc3cccnc3)CC2)cn1 +Cc1ccccc1CC(=O)Nc1ccc2c(c1)oc(=O)n2C(C)C +Nc1ccc2nc(SCC(=O)NCCc3ccccc3)sc2c1 +Cc1cc(COC(=O)c2ccc(Cl)c(N)c2)no1 +O=C(NCc1cscn1)N1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1ccccc1NCc1cc(C(N)=O)ccc1F +CCCCNC(=O)N1CCN(c2nc(C)nc3c(C)nn(C)c23)CC1 +CCC(C)NS(=O)(=O)c1cc(OC)c(Cl)cc1OC +Cc1c(Cl)cccc1NC(=O)C1CC(=O)N(C(C)C)C1 +C=CCNC(=O)c1ccccc1NC(=O)c1cc(SC)ccc1C +COc1cc(C)ccc1OCCC(=O)NC(C)c1cc(C)oc1C +COc1ccc(CNC(=O)c2cc(-c3ccncc3)n[nH]2)c(F)c1F +Cc1noc2nc(C(C)C)cc(C(=O)N(C)CC(=O)NC(C)(C)C)c12 +CC(=O)N1CCc2ccc(NC(=O)Cc3ccsc3)cc2C1 +Cc1cc(C(C)C(=O)N2CCCCC2Cn2cccn2)c(C)o1 +Cn1cnnc1SCCC(=O)NCC1CCCO1 +Cc1cc(NC(=O)c2cccc(OCc3ccccc3C#N)c2)n(C)n1 +CCC(C(=O)Nc1ccccc1F)n1nnc2ccccc2c1=O +CC(=O)NC(C(=O)OCc1noc(-c2ccc(C)cc2)n1)C(C)C +CC(=O)c1cccc(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)c1 +O=C(c1cccc(N2CCCC2=O)c1)N1CCCC(c2ccn[nH]2)C1 +c1cc2c(cc1-c1nc3ncc4c(n3n1)CCC4)OCCCO2 +CCOc1c(Cl)cccc1NC(=O)Nc1nccs1 +CC(C)CCCC(C)NC(=O)c1csc(S(N)(=O)=O)c1 +Cc1noc(-c2cccc(NC(=O)COc3ccc(Cl)cc3)c2)n1 +CCOCCNC(=O)c1cccc(Br)c1 +CC(C)N(C)C(=O)c1cccc(S(=O)(=O)N2CCCCCC2)c1 +CN(c1ccc2ccccc2c1)S(=O)(=O)c1cn[nH]c1 +CN(C)c1ccc(C2CCN(c3cnccn3)CC2)nc1 +CCc1ccccc1CNS(=O)(=O)CC(C)CC +N#Cc1ccc(NCCc2ccc3c(c2)OCO3)nc1 +COc1cccc(N(CC(=O)Nc2cccc(C)c2)S(C)(=O)=O)c1 +O=C(NCc1ccco1)c1nnc2ccc(Cl)cc2n1 +O=C(CNC(=O)c1cccc(Cl)c1)c1ccc2c(c1)CCC2 +Cc1oc(-c2ccccc2)nc1CC(=O)OCC(=O)NC(C)C +COC(=O)c1cn(-c2ccccc2NC(=O)c2cnc(C)cn2)nn1 +CN(C)c1ccc(NC(=O)Cn2cc(-c3ccccc3)nn2)nc1 +c1ccc(-c2nc(CSc3nnnn3C3CCOCC3)co2)cc1 +COc1ccc(CNC(=O)Nc2nnc(C)s2)cc1O +CC(NC(=O)CCSc1nc2ccccc2s1)C1CCCO1 +CC(C)c1ccc(C(=O)CSc2ncc(C#N)c(N)n2)cc1 +CCN(CC)C(=O)CN(c1ccc(C(C)C)cc1)S(C)(=O)=O +Cc1cc(NC(=O)NC2CCCCNC2=O)no1 +CC#CC1NCCc2cc(OCC)c(O)c(Cl)c21 +Cn1c2ncccc2c(=O)n1CCOc1ccccc1F +Cn1ncc2c(NCCCSc3ccc(F)cc3)ncnc21 +COCC(C)OC(=O)C(C)Oc1ccc(F)cc1Cl +CCCc1nc(C(=O)N2Cc3ccccc3CC2C(N)=O)cs1 +Cc1ccc(-c2csc(NC(=O)c3cnccn3)n2)c(C)c1 +CC(C)(C)CCNC(=O)CN1CCc2cc(S(N)(=O)=O)ccc21 +NC(=O)C1CCN(C(=O)c2ccc(F)cc2N)CC1 +CCCCNC(=O)CSc1nc(C)nc2sc(C)c(C)c12 +CCn1nc(CC(C)C)cc1C(=O)NC(C)Cc1ccsc1 +COc1ccc(C(C)=O)c(OC(=O)C2(C)CC2(Cl)Cl)c1 +Cc1noc(C)c1C(C)NC(=O)CC12CC3CC(CC(C3)C1)C2 +CCC(=O)N1CCN(C(=O)CC2CCC(C(F)(F)F)CC2)CC1 +O=C(c1ccncc1F)N(Cc1cccc(F)c1)C1CC1 +Cc1ccc(CN2CC(C(=O)NCC(=O)NC3CC3)CC2=O)cc1 +CC(C)(CNC(=O)c1ccc(F)cc1F)c1ccncc1 +COC(C)(C)c1noc(CCNC(=O)N(C)Cc2ccccc2)n1 +N#CC(NC(=O)c1ccc2c(c1)CCCC2)C1CCOC1 +O=C(Nc1cnccn1)c1csc(C2CCCO2)n1 +Cc1cc(C)n2nc(CC(=O)Nc3cccc4cn[nH]c34)nc2n1 +COc1cccc(OC2CN(C(=O)C3CCCN3C(N)=O)C2)c1 +COc1ccc(OCCN(C)C(=O)NCc2cccnc2)cc1 +O=C(CCn1ccc2ccccc21)Nc1ncn(Cc2cccnc2)n1 +COc1ccccc1CN1CCN(C(=O)c2ccc(C)cc2O)CC1 +Cc1ccc(NC(=O)C2CCCN2C(=O)c2cccc(F)c2)cc1C +Cc1cccc(NC(=O)CN(CCc2ccccc2)S(C)(=O)=O)c1 +CS(=O)(=O)c1cccc(OC(=O)C2CC2c2ccccc2)c1 +CN(c1ccccc1)c1ccccc1NC(=O)c1ccccn1 +CC(=O)Nc1ccc(SCCN2CCOC2=O)cc1 +Cc1cc(=O)c(C(c2cccs2)c2c(O)cc(C)oc2=O)c(O)o1 +CCN(Cc1cccs1)C(=O)CNC(=O)c1cccc(Cl)c1 +Cc1ccc(NC(=O)COC(=O)c2ccc(C)nc2)c(C)c1 +Cc1ncsc1CN1CCC(OC2CCOCC2)CC1 +CC(Sc1ccccc1Cl)C(=O)N1CCCC1 +CC(C(=O)NC1CCCCC1)N1Cc2ccccc2C1=O +COCCNC(=O)CNC(=O)Cc1ccccc1 +COc1ccccc1NCC(=O)Nc1cc(C)ccc1OC +CCCCOc1cccc(NCc2cccnc2)c1 +CCOCCCNC(=O)CC1CSc2nc(C)cc(=O)n21 +C=CCn1c(SCc2nnc(SC)o2)nnc1-c1ccccc1 +CC(CCO)NC(=O)Nc1ccc(Cl)c(Br)c1 +CCOC(=O)CN(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +CN1CCCC2(CCN(Cc3cnc(N4CCOCC4)nc3)C2)C1=O +O=c1c(=Cc2ccco2)sc2nc(-c3ccc(F)cc3)nn12 +CC(C)Cc1ncc(CNc2ccc3c(c2)OCC(=O)N3)s1 +CC(=O)Nc1ccc(NC(=O)Cc2ccc(-n3cnnn3)cc2)cc1 +OCC(O)CN1CCNc2cc(Br)ccc21 +CCC(C)n1ncc(C(=O)Nc2cc(F)cc(F)c2)c1C1CC1 +CC(C)N(C)c1nc(N)c(C#N)c(C(C#N)Cc2ccccc2)c1C#N +Cc1nc(NC(=O)COc2ccccc2Br)sc1C +CC(CNC(=O)Nc1ccccc1C(F)(F)F)CN1CCCC1=O +Cc1ccc(C(C#N)NS(=O)(=O)c2c(C)noc2C)cc1 +c1ccc(-c2nnnn2-c2ccn(-c3ccccc3)n2)cc1 +COC(=O)C(CC(C)C)NC(=O)C1CC1c1ccco1 +CC(=O)c1ccc(C(=O)Nc2cc(C)nn2-c2ccc(C)nn2)cc1 +Cc1ccc(Cn2ccccc2=NC(=O)c2ccc(=O)n(C)c2)cc1 +CN(C(=O)CCCNC(=O)c1ccc(F)cc1)c1ccc(Cl)cn1 +O=C(Cn1cnnn1)Nc1ccc(Br)cc1 +Cc1ccc(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)cc1Cl +CC(Cn1cncn1)NC(=O)N1CCN(C(C)c2ccccn2)CC1 +O=C(NC1CCCCC1)N(Cc1cccnc1)Cc1cccnc1 +CCC(=O)N1CCN(S(=O)(=O)c2cc(C)ccc2C)CC1 +Nc1ccc(-c2nc3cc4[nH]c(-c5ccc(N)cc5)nc4cc3[nH]2)cc1 +CC(Oc1cccc(C#N)c1)C(=O)N1CCCCC1Cn1cccn1 +COc1cc(NC(=O)c2ccc(C)s2)cc(OC)c1 +O=C1NC(c2cccc(Cl)c2)c2c1oc1ccccc1c2=O +CCN1CC(C(=O)N2CCC(Nc3cccc(OC)c3)CC2)CC1=O +C=CCNC(=O)CSc1ncnc2sc3c(c12)CCC3 +O=C(CSc1ccc(F)cc1)NCc1ccc(-n2cccn2)cc1 +O=C(Cc1noc2ccccc12)N1CCN(c2ccc(F)cc2)CC1 +CCCCN(C)C(=O)CC(NC(N)=O)c1cccs1 +CC1=C(C(=O)NCCCc2nnc3ccccn23)Cc2ccccc2O1 +NC(=O)c1cccc(S(=O)(=O)Oc2ccc(F)cc2F)c1 +CC(O)c1cc(F)ccc1N(C)C1CCOCC1 +Cc1cccc(C)c1C(=O)NCCc1nccs1 +CS(=O)(=O)N1CCCC1C(=O)Nc1ccc(F)c(F)c1 +COCCCNC(=O)Nc1cccc(Cl)c1Cl +CNc1cccc2c(OCC(F)(F)F)nccc12 +Cc1cc(C)n(Cc2cccc(C(=O)NC3CC(=O)N(C)C3)c2)n1 +CC1CN(C(=O)CNC(C)c2cccc(OC(F)F)c2)CC(C)O1 +CCC(=O)Nc1ccc(NCC(=O)N(C)c2ccccc2)cc1 +CC(NC(=O)Cc1ccc(F)c(F)c1)c1cccc(-n2cccn2)c1 +CCOC(=O)c1cnc2nc(SC)nn2c1-c1ccc(OC)cc1 +Cc1noc(C)c1C(C)NC(=O)CNC(=O)CCC1CCCC1 +COC(=O)C(NC(=O)c1oc(C)cc1C)c1ccc(Cl)c(F)c1 +C=CCOC(C)C(=O)Nc1cc(C(=O)OC)ccc1C +Cc1cc(C(=O)N(CC(F)F)c2cccc(Cl)c2)nn1C +O=C(NCc1ccncc1)N(CC1CC1)C1CCCCC1 +CCn1c(C(=O)Nc2ccon2)cc2sccc21 +C=CCN(CC=C)C(=O)c1cnc(C2CCCO2)nc1N +Clc1cc(Cl)c2c(c1)CCNC2c1cc[nH]c1 +O=C(NC1CCCC1)c1ccc(OC(F)(F)F)cc1 +Cc1[nH]c(-c2ccccc2)nc1-c1nc(C2CCOC2)nn1CCO +CN(Cc1ccccn1)C(=O)NCc1nncn1-c1ccccc1 +CC(C)n1ccc(-c2nnc(NC(=O)c3cccc4ccccc34)o2)n1 +O=C(CC1CCCC1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CN(Cc1cncs1)C(C(N)=O)c1cccc(Br)c1 +CC(NC(=O)CN1C(=O)COc2ccccc21)c1ccccc1 +OCCn1ncc2c(NCc3cnn(Cc4ccccc4)c3)ncnc21 +CN1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1 +COc1ccccc1CN(C(=O)NCc1ccco1)C1CC1 +CC1CCN(c2ncnc3c2cnn3CC(=O)NC2CCCC2)CC1 +Cc1c(C(=O)N2CCCS2(=O)=O)cnn1-c1ccccc1 +CC(C)NC(=O)C1CN(C(=O)Nc2ccccc2)CC12CCOCC2 +CCc1ccc(S(=O)(=O)N(CCCO)C(C)C)s1 +CC(C)NC(=O)NC1CC(=O)N(CCc2cccc(Cl)c2)C1 +CNC(=O)c1ccccc1NC(=O)Cc1ccc(Cl)cc1 +CCN(Cc1ccc(OC)c(OC)c1)S(N)(=O)=O +CC(=O)Nc1cccc(NC(=O)Cc2c[nH]c3ccccc23)c1 +N#CCc1nc(CCn2ccc3ccccc32)no1 +Cc1ccc(N2CC(C(=O)n3nnc4ccccc43)CC2=O)cc1C +Cc1ccc(F)c(C(=O)NC(c2nccs2)C2CC2)c1 +COc1ccc(CCC(=O)N2CCc3ccc(N)cc32)cc1 +CC1(CNC(=O)NC2CCC3(CC2)OCCO3)CCCC1 +COc1ccc(C(N)=O)cc1NS(=O)(=O)c1ccc(F)cc1C +CC1CN(C(=O)c2ccc(-c3ccc(Cl)cc3)o2)CCO1 +Cc1ccc(CCC(=O)N2CCNC(=O)C2C(C)C)c(C)c1 +O=C(c1cnc2sc3c(n2c1=O)CCC3)N1CCc2ccccc21 +Cc1cc(C(=O)OCC(=O)NC2CCC(C)CC2)c(C)n1C(C)C +CCOC(=O)Nc1nnc(Sc2nccnc2C#N)s1 +CC(CCc1ccccc1)NC(=O)c1csnn1 +Cc1nnc(NC(=O)CCOc2ccc(F)cc2F)s1 +CC(C)(C)c1noc(CCC(=O)NCCc2ccccn2)n1 +O=C(CC1C(=O)Nc2ccccc21)NCc1cccnc1 +CCc1cccc(C)c1NC(=O)c1ccn(-c2ccccc2F)n1 +CCC(=O)N1CCC2(CCN(Cc3cccc(F)c3)C2=O)C1 +Cc1n[nH]c2c1C(c1cccc(F)c1)C1=C(COC1=O)N2 +COCCNC(=O)CNC(=O)c1n[nH]c2ccccc12 +Cc1cc(OCC(=O)NC(C)(C)CO)cc(C)c1Cl +CC(C)CNC(=O)c1c(Br)cnn1C(C)C +COc1ncccc1CNC(=O)C1COc2ccc(Cl)cc2C1 +CNc1snc(C)c1C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +O=C(OCC1CCCCO1)c1cccc(NC(=O)C2CC2)c1 +Cc1cc(NC(=O)CCCn2cccn2)ccc1Br +Cc1cccc2c1C(CNC(=O)c1ccccc1)NCC2 +CS(=O)(=O)NCCNc1nc2ccc(N)cc2s1 +CCN(CC)c1ccc(CCC(=O)N2CCCC(C)C2)cc1N +O=C(Nc1ccccc1F)NC1CCCc2ccccc21 +CC(C)c1ccc(SCCC(=O)Nc2sccc2C(N)=O)cc1 +CC(=O)N1CCN(C(=O)c2ccc(Cl)cc2N)CC1 +N#Cc1cccc(CNC(=O)CCNC(=O)c2n[nH]c3ccccc23)c1 +CN(C)C(=O)CNC(=O)c1cccc(-c2nnnn2C)c1 +COc1ccc(NC(C)=O)cc1NC(=O)Cc1ccc2c(c1)OCC2 +CN1CCN(C(=O)c2cc(-c3ccncc3)nc3ccccc23)CC1 +COc1ccc(NC(=O)c2ccc(C)cc2C)cc1OC +CCOc1ccccc1-c1cc(C#N)nn1CCCC#N +Cc1ccccc1C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +Nc1ccc(F)cc1NS(=O)(=O)c1ccccc1F +CCc1nc2cc(N3CCCC(C(=O)N(C)C)C3)cnc2nc1CC +Cc1cc(C(=O)Nc2cccc(C#N)c2)c2c(C)noc2n1 +COc1cc(CNC(=O)N2CCC(Oc3ccccc3)CC2)ccn1 +O=C(Cc1cccs1)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +CCNC(=O)N1CCN(CC(=O)NC(C)COC)CC1 +COc1cc(CN(C)Cc2cncs2)ccc1SC +O=C(COc1ccc(F)cc1)NCC(c1ccco1)N1CCOCC1 +CC(Cc1ccncc1)Nc1cc(-c2ccc(F)cc2)nc2ccnn12 +CCC(C)NC(=O)CN1CCN(C(=O)Cc2cccc(O)c2)CC1 +Cc1sc2ncnc(OCc3ccc(C#N)cc3)c2c1C +CS(=O)(=O)N1CCCn2nc(CNC(=O)c3ccc[nH]3)cc2C1 +CC(C)c1nc2oc3c(=O)n(C)cnc3c2c2c1CCCC2 +O=C(Cc1c(F)cccc1F)NCCc1ccccn1 +CC(C)(C)OC(=O)N1CCC(C(=O)NCc2cccnc2)CC1 +O=C(Cc1ccc[nH]1)Nc1cccc(Br)c1 +C=CCNC(=O)c1snc(-c2ccc(C)cc2)c1N +O=C(Nc1cccc(F)c1)c1ccnc(-c2ccsc2)c1 +NC(=O)c1ccc(NC(=O)Nc2ccccc2F)cc1 +Cc1noc(C)c1CN1CCOC2CN(C(=O)N3CCCC3)CC21 +CCC(NS(=O)(=O)c1cnn(C(C)C)c1)c1ccccc1 +Cc1nn(C)c2nc(NCc3nc(Cc4ccccc4)no3)sc12 +CCOC(=O)c1cc(C(=O)OC)n2ccc3ccccc3c12 +O=C(Cc1cccc(F)c1)N1CCN(c2ncccn2)CC1 +COc1cc(C)c(C(=O)N2CCC(n3cncn3)CC2)cc1OC +CC1COCCN1C(=O)NC1CCCC(C(F)(F)F)C1 +CN(C(=O)Cn1c(=O)c2c(ncn2C)n(C)c1=O)C1(C#N)CCC1 +Nc1cc(=O)[nH]c(SCc2cccc(Br)c2)n1 +COc1cc(N)ccc1NC(=O)c1cc2c(s1)CCC2 +COc1ccc2c(c1)nc(CC#N)n2Cc1ccc(F)cc1 +COc1ccc(OC)c(-c2csc3nc(CO)cn23)c1 +Cc1cc(C(=O)N2CCN(CC(=O)Nc3ccccc3)CC2)no1 +CCOc1ccccc1CNC(=O)c1cccc(S(=O)(=O)NC)c1 +COc1ncccc1CNC(=O)c1cccc2c1OC(C)C(=O)N2 +Cc1cccc(CCNC(=O)c2ccc3[nH]cnc3c2)c1 +Cc1ccoc1CN1CCOC(c2cnn(C)c2)C1 +N#Cc1ccc(NC(=O)c2nn3ccccc3c2Cl)cc1 +COCCc1noc(N)c1-c1ccc(OC)c(F)c1 +CC(C)N(C(=O)CSc1nc2sccc2c(=O)[nH]1)C(C)C +Cc1ccc(S(=O)(=O)N2CCCC(Cn3cncn3)C2)cc1C +Cc1nc(N(C)Cc2ccccc2)c(C#N)c(C)c1N +CCOC1CC(NC(=O)Nc2cnccc2C)C12CCC2 +CCC(C)C(NC(=O)C(C)NC(=O)c1ccoc1)C(N)=O +CCc1ncc(C(=O)NCCN2CCCS2(=O)=O)s1 +COc1cccc(CNC2=NC=NC3=NC=NC32)c1 +O=C(C1CC=CCC1C(=O)N1CCOCC1)N1CCCCC1 +Cc1cc(C)n(-c2ccc(NC(=O)CNS(C)(=O)=O)cn2)n1 +CCc1noc(CN(C)CCc2nc(-c3cccc(Cl)c3)no2)n1 +COc1cc2nc(-c3ccccc3)n(CCCC#N)c2cc1OC +CCOCCNC(=O)NC(C)c1csc(C2CC2)n1 +Cc1cccnc1-n1c(SCC#N)nc2ccccc2c1=O +CCC(=O)Nc1cccc(C(=O)Nc2cccnc2)c1 +CCCN1C(=O)CC(C)S(=O)(=O)c2ccccc21 +O=C(Nc1ccc(Cl)cc1)c1ccc(-n2cccn2)cc1 +CCOC(=O)Cc1nnc(Sc2ncnc3sccc23)n1C +C=CCNC(=O)NCCCSc1ccc(F)cc1 +Cc1nc(N)nc(-c2ccc3c(c2)NC(=O)CCO3)n1 +CCc1cccc(NC(=O)Cn2cc(Br)ccc2=O)c1 +CC(C(=O)NCc1ccc(Oc2ccccc2)cc1)n1cncn1 +O=C(Nc1ccc2c(c1)CCC2)NC1C2CCC(C2)C1CO +O=C(NCC1CCCO1)c1ccccc1SCC(=O)N1CCCC1 +O=C1C2CCCN2C(c2ccccc2)N1c1nccs1 +CC(=O)N1CCCN(C(=O)c2nc(C(C)C)ncc2Cl)CC1 +Cc1ccccc1C(=O)NCC(O)c1ccccc1C(F)(F)F +COc1ccccc1CN1C(=O)C(C)(C)CS1(=O)=O +Cc1nccn1CCN1CCN(CC(=O)N(C)c2ccccc2)CC1 +CC(=O)c1ccc(NC(=O)c2ccc3ccccc3n2)cc1C +CCc1cccc(OC(C)C(=O)Nc2ccc(C(N)=O)cc2)c1 +COc1ccccc1CNC(=O)Nc1ccc2c(c1)OCCO2 +Cc1nnc(CNC(=O)c2cc(Cl)ccn2)o1 +CC1CN(c2ccc(C(=O)NCCCn3cccn3)cn2)CC(C)O1 +N#CC1(C(=O)N2CC=C(c3ccccc3Cl)CC2)CCC1 +Cn1cc(CC(=O)N2CCCC2c2ccccn2)c2ccccc21 +CCC(CC)NC(=O)Nc1ccc(C)c(N2CCCS2(=O)=O)c1 +CCN(Cc1ccccc1)C(=O)CSc1nnc(C)n1CC +O=C(Nc1cccc2cn[nH]c12)c1cccc(NC(=O)c2ccco2)c1 +N#Cc1cccc(NC(=O)COc2ccc(Br)cc2)c1 +CCOCCSc1nc2ccsc2c(=O)n1CC +COc1cc(C#N)ccc1OCc1nc(Cc2ccccc2)no1 +COc1cc(O)cc2c1C(=O)C(Cc1ccc(O)cc1)CO2 +CSc1nc(-c2ccco2)nn1C(=O)c1ccc(F)cc1 +CCN1C(=O)CCc2cc(NC(=O)CC(C)C)ccc21 +Nc1ccc(SCC(=O)Nc2ccccc2)cc1 +COC(=O)c1ccc(Cl)c(CN(C)Cc2cc(C)on2)c1 +CC(C)(NC(=O)c1cccc(OCC(N)=O)c1)c1cccc(Cl)c1 +COC(=O)c1ccc(NC(=O)Oc2ccccc2)cc1 +O=C(COC(=O)c1ccco1)c1ccc(Br)cc1 +NC(=O)C1CN(Cc2cnc(-c3ccsc3)s2)CCO1 +CCCOCC(=O)NCC(O)c1c(Cl)cccc1Cl +COc1ccc(Cl)cc1NCCC(=O)N1C(C)COCC1C +Cc1ncsc1C(=O)N1CCN(CC(O)c2ccccc2)CC1 +CC(C)(C)OC(=O)N1CCCC(Oc2nccs2)C1 +N#Cc1ccc(-c2noc(-c3ccc(F)c(F)c3)n2)nc1 +COc1cc(N2CCC3(CC2)CC(Nc2cnn(C)c2)CO3)ncn1 +c1csc(C2CCCN(c3ncnc4[nH]cnc34)C2)n1 +Cc1sc(=O)n(CC(=O)N2CCCCCC2c2cccn2C)c1C +CN(C)c1ccc(NC(=O)c2cccc(Cl)c2Cl)nc1 +Cn1nc(C(=O)NCC(=O)N2CCCCC2)c(=O)c2ccccc21 +O=C(c1cc(Cl)c[nH]1)N1CCCN(c2cccnn2)CC1 +CCNC(=O)CNC(=O)Nc1ccc(C(F)(F)F)cc1 +COc1c(NC(=O)NCC(C)c2ncc(C)s2)c(C)nn1C +CC(C)Oc1cccc(C(=O)Nc2cccc(C(N)=O)c2)c1 +COCCNC(=O)C(N)c1cccc(F)c1OC +CCCOc1ccccc1NC(=O)NC1CCCc2occc21 +C=CCN(CC(F)(F)F)C(=O)Nc1ncc(C)s1 +CC(=O)Nc1ccc2c(c1)nc(CCNC(=O)C1CCCO1)n2C +COc1cccc2c1CCN(C(=O)c1ccco1)C2 +Cc1cccc(CN2CC3CN(C(=O)NC4CC4)CC3C2=O)c1 +O=C(Nc1cccc(OCC(F)F)n1)C1CCOCC1 +O=C(NCCC1CC1)Nc1ccc(Oc2cccnc2)nc1 +CSc1ccc(C2C(C(C)=O)C(=O)CC(C)(O)C2C(C)=O)cc1 +Cc1c(C(=O)N(C)C2CC2)nnn1-c1ccc(F)cc1 +CCOC(=O)CN(CC)C(=O)Nc1cccc(N)c1 +CC1(C)CC2CC(C)(CN2C(=O)C(C)(C)NC(=O)c2cccs2)C1 +CCCn1c(C)nnc1SCc1ccc(F)c(C#N)c1 +COc1ccccc1-c1nnc(NC(=O)c2c(F)cccc2F)o1 +c1ccc(CCNCc2ncc(-c3cccnc3)s2)cc1 +Cc1ccc(C(=O)NCCCNC(=O)c2cc3ccccc3o2)cn1 +CC1Cc2ccccc2CN1C(=O)c1cccc2c1oc(=O)n2C +Cc1nc2ccccn2c1C(=O)Nc1ccc(CC(N)=O)cc1 +O=C(CNC(=O)Cn1cncn1)NCc1ccccc1 +Cn1cccc(NC(=O)Cc2ccccc2Cl)c1=O +CCC(NC(=O)N1CCN(C(=O)c2ccoc2)CC1)c1cccs1 +CN(C)c1ccc(C(=O)NCCC(=O)N2CCCC2)cn1 +COCc1nc(N2CC3(C)CC2CC(C)(C)C3)c2cnn(C)c2n1 +Cc1cc(C)nc(C2CCCN2C(=O)c2cnccn2)n1 +NC(=O)C1(Oc2cc(Cl)cc(Cl)c2)CCCC1 +O=C(Nc1ccc2c(c1)COC2)c1cc(-c2ccccc2)[nH]n1 +Cn1nc2c(c1NC(=O)Cc1ccc(OC(F)F)cc1)CCC2 +CNS(=O)(=O)c1cccc(C(=O)OCC(=O)Nc2ccccc2)c1 +Cc1c(C(=O)N2CCCC2(C)C)cnn1-c1ccc(F)cc1 +Cc1nn(C)c(C)c1CCC(=O)NCc1ccccn1 +O=C(NCCc1nnc(-c2ccccc2)o1)c1cccc2cccnc12 +O=C(NCCCn1cncn1)N1CCC1c1ccccc1 +CC1(C)CC(N(Cc2cccs2)C(=O)c2ccco2)CCO1 +CCCNC(=O)c1ccc(NC(=O)C2CCCCN2C(=O)CC)cc1 +CC(=O)N1CCC(C#N)(NCc2ccc(C)cc2)CC1 +N#Cc1ccc(NC(=O)c2ccccc2OCC(N)=O)cc1Cl +CCOCC1CC2(COCCN2C(=O)c2ccc(CC)cc2)CO1 +CCOC(=O)C(CC(C)C)Nc1ncnc2onc(C)c12 +CCc1cc2c(CN(C)CCOC)cc(=O)oc2cc1O +CCc1noc(CNc2ccccc2-n2cccn2)n1 +CCOC(=O)c1cnc(-c2ccc(F)cc2)nc1N +CNc1ccc(Oc2c(F)c(F)nc(F)c2F)cc1 +CC(C)c1ccc(S(=O)(=O)Nc2ccc(-n3cnnn3)cc2)cc1 +COc1cccc(-n2nnc(-c3cccnc3)c2N)c1 +COc1ccc(NC(=O)c2scnc2C)c(N)c1 +CCC(C)n1ncc(C(=O)Nc2nc(C)ns2)c1C1CC1 +COCCOCC(=O)N1CCCC(C)(C)c2ccccc21 +O=c1ccc(-c2ccc(S(=O)(=O)Nc3ccccc3)o2)n[nH]1 +Cc1ccc(N(Cc2ccccc2)C(=O)c2cnccn2)cc1 +O=C(CCc1ccccc1)Nc1nnc(C2CCC2)s1 +COc1ccc(C(=O)OCC(=O)Nc2ccccc2OC)cn1 +CC1CC(C)CN(C(=O)C(C)S(=O)(=O)c2ccccc2)C1 +CCNC(=O)c1cccc(NC(=O)c2cn3ccccc3n2)c1 +Cc1cc(C(=O)NCC(=O)Nc2ccn(C)n2)nn1C +Cc1csc(SCc2noc(C(C)(C)C)n2)n1 +Cn1cccc(C(=O)OCc2cc(-c3ccco3)on2)c1=O +CCNC(=O)c1cccc(-n2cc(Br)cn2)c1 +COc1ncccc1C(=O)OCc1nc(C)c(C)o1 +COC(=O)C1=C(C(C)C)NC(=O)NC1c1cccc(F)c1 +C#CCOc1ccc(CCNS(=O)(=O)c2ccc(F)cc2)cc1 +COc1ccc(C(=O)Nc2nc3c(s2)CCCC3C(N)=O)cc1 +COC(=O)CCSc1nnc(-c2ccncc2)n1C1CC1 +COC(=O)c1ccc(C)c(NC(=O)COc2ccc(OC)cc2)c1 +CCC(CC)c1nc(C#N)c(C#N)nc1-c1ccc(OC)c(OC)c1 +Cc1nc2cc(NC(=O)C(C)NC(N)=O)ccc2[nH]1 +O=C(c1cccc(F)c1Cl)N1CCC(C2OCCO2)CC1 +Cc1cn(C)c(=O)c(C#N)c1-c1ccc2c(c1)OCCO2 +CCc1cc(=O)n(CC(=O)NCc2ccccc2OC)c(N)n1 +CN(C)S(=O)(=O)NCc1cnn2ccccc12 +CC1(C)Cc2cccc(OCC#CCNS(=O)(=O)C3CC3)c2O1 +CCOC(C)C(=O)NCc1cccc(CN2CCCC2=O)c1 +COc1ccc(C(=O)OCC(=O)c2[nH]c(C)c(C(C)=O)c2C)cn1 +CCCCCC(=O)NC(C)c1nnc2n1CCCCC2 +Cc1cccc(C(CNC(=O)Nc2ccncc2)N2CCOCC2)c1 +Cc1cc(NC(=O)c2cccc(Oc3ccccc3)c2)no1 +Cc1ccc2c(c1O)CCNC2c1ccc(F)c(C#N)c1 +CC(CC(=O)N1CCCC(c2cc(C(N)=O)[nH]n2)C1)n1cccc1 +N#Cc1c(N)nc2c(c1-c1ccc(-c3cc[nH]n3)s1)CNCC2 +NC(=O)c1ccccc1OCC(=O)NCC(F)(F)F +CC(=O)c1ccc(NC(=O)c2cccn2Cc2noc(C)n2)cc1 +Cc1csc(CNCc2nc3ccsc3c(=O)[nH]2)n1 +CC(C)(C)OC1CCN(C(=O)c2cccnc2OCC(F)F)CC1 +C=CCCCN(C)C(=O)CCN1C(=O)C(C)Oc2ccccc21 +CC(=O)Nc1ccc(C#CCNC(=O)COc2ccccc2)cc1 +CC1CN(C(=O)CNC(=O)c2cccs2)CC(c2ccccc2)O1 +Cc1nc(-c2c(O)cccc2F)sc1CCO +Cc1cc(N2CCC(=O)CC2)nc(-c2cccnc2)n1 +CC1=CCC(CC2CCCO2)(S(=O)(=O)c2ccccc2)CC1 +Cc1cn(-c2ccccc2)nc1NC(=O)CCSc1ccccn1 +Oc1cc2c(cc1F)CCNC2Cc1c[nH]c2ccccc12 +O=C(c1cccnc1-c1nc2ccccc2s1)N1CCCC1 +Cc1cccc(NC(=O)N(C)Cc2ccoc2C)c1C +Cc1cc(C)n(C(=O)c2c(Br)cnn2C)n1 +O=C(c1ccccn1)N1CCCC2(CCCCC2)C1 +Cc1cc(C)c(NC(=O)Cc2csc(-c3ccccn3)n2)c(C)c1 +CS(=O)(=O)NCc1ccc(NC(=O)c2ccc(F)c(F)c2)cc1 +CCn1c(=O)c2c(nc3n(-c4ccccc4)c(C)cn23)n(C)c1=O +CC(C)CN(CC(N)=O)S(=O)(=O)c1ccc(O)cc1 +COc1cc(C)c(S(=O)(=O)Cc2nc(C)cs2)cc1OC +C=CCN(Cc1cccs1)C(=O)Cn1cccc(C)c1=O +CC(C)c1csc(C(=O)N2CCC3(CC2)NCCNC3=O)n1 +CCOC(=O)CC(C)CNC(=O)N1CCCC1C1CCC1 +CCC(=O)Nc1ccc(Cl)c(NCc2nnc(C(C)(C)C)o2)c1 +CCOC(=O)C(C)NS(=O)(=O)c1ccc2c(c1)CCC2 +O=C(Nc1ccn(-c2ncccc2Cl)n1)c1ccccn1 +Cc1occc1-c1nnc(SCC(=O)c2ccc(F)c(F)c2)n1C +CCc1nnc(NC(=O)CCc2ccc(-c3ccccc3)o2)s1 +CC(C)CNC(=O)c1ccc(C(=O)NC(C)(C)C)cc1 +CC(C)CC(C)N(C)C(=O)c1cccc2cn[nH]c12 +CCc1ccc(CNC(=O)c2cc(OC)c(OC)cc2OC)s1 +CCOC(=O)Cn1c(=O)c2ccccc2n(Cc2ccccc2)c1=O +O=C(NCc1ccco1)N1CCN(S(=O)(=O)c2ccccc2)CC1 +Cc1cc(Br)ccc1NC(=O)CNC(=O)c1cnn[nH]1 +COc1ccc(CCNC(=O)COc2ccc(F)cc2)cc1 +COc1cc(CN(C)C(C)CC#N)ccc1OC(C)C +Cc1nc(C)n(CC2CCCN2c2nnc(C)c(C)c2C#N)n1 +Cc1nc(C)n(CCOc2ccc(C(C)C)c(C)c2)n1 +CNS(=O)(=O)c1ccc(C(C)NC(=O)c2ccoc2C)cc1 +O=C(c1ccc[nH]1)N1CCc2ncnc(Oc3cccnc3)c2CC1 +O=C(CNCc1cccnc1)NCCc1ccccc1 +CC(=O)NCc1ccc(S(=O)(=O)N2CCOCC2)cc1 +CN(C(=O)c1cc(-c2ccco2)[nH]n1)C1CCCCC1 +CC1C(=O)NCCN1C(=O)c1cccc(S(C)(=O)=O)c1 +CCCNC(=O)Cn1ncn2nc(-c3ccco3)cc2c1=O +CC(c1cccs1)N(C)CCC(=O)OC(C)(C)C +COc1cc(C(=O)Nc2cccc(-c3nc(C)cc(=O)[nH]3)c2)ccc1C +Cc1cc(CN(C)C(=O)NC2CCc3c(F)cccc32)no1 +CCOc1ccc(-c2nc(C(=O)NCc3ccco3)cs2)c(F)c1 +CC(C)(C)OC(=O)CNC(=O)Nc1ccccn1 +Cc1c(C(=O)NCCC(=O)N2CCCC2)nc2cc(Cl)ccn12 +CCCOc1cccc(C(C#N)NCc2ccco2)c1 +O=C(Cc1ccc(F)cc1F)NCCCn1cccn1 +Cc1ccc(-n2nnc(C(=O)N3CC(=O)Nc4cccnc43)c2C)cc1 +CCCSc1nc(C(C)C)nc2c1c(=O)n(C)c(=O)n2C +Cc1nn(C)c(C)c1S(=O)(=O)N1CCC(CC(N)=O)CC1 +N#CCOc1cccc(CC(=O)N2CCCC(c3nccs3)C2)c1 +CCc1noc(CC)c1CNC(=O)NCC(O)c1ccccc1C +CNC(=O)C1CCCCN1S(=O)(=O)c1ccc(C(=O)OC)cc1 +COCCN1CC(C(=O)N2CCCC2c2cc(C)no2)CC1=O +CCOC(=O)c1ccc(NC(=O)c2nc(C(C)C)oc2C)cc1 +N#Cc1ccc(C(=O)N2CCOc3ccc(F)cc32)cc1 +CCOC(=O)COC(=O)Cc1coc2cc(C)c(C)cc12 +CCn1ccc2sc(C)c(C(=O)N3CCCC3)c2c1=O +CN(C)C(=O)CN1CCOC(c2ccc(Cl)c(Cl)c2)C1 +N#CC(NC(=O)CCn1c(=O)oc2ccccc21)c1ccccc1F +O=C(Cn1nc2ncccn2c1=O)Nc1ccc2c(c1)OCO2 +O=C(CSc1nnc2ccccn12)N1CCOCC1 +CCCNC(=O)N(Cc1cccnc1)Cc1ccccn1 +Cc1cc(Oc2ccccc2)nc(-n2nc(C)cc2C)n1 +COc1ccc2nc(NC(=O)C3CC(=O)N(C(C)(C)C)C3)sc2c1 +COc1ccc(CNC(=O)NCc2sccc2C)cn1 +CCOC(=O)c1sc(NC(=O)c2cccc(C)n2)cc1C +COc1ccccc1CC(C)(C)NC(=O)C1CC2CCC1O2 +CCS(=O)(=O)NC1CCC(Oc2ccccc2C#N)CC1 +CNC(=O)c1c(C)nc(N)nc1COc1ccccc1C(C)(C)C +COCCN(CCOC)C(=O)c1sc(C)nc1C +C=CCNc1nnc(SCc2ccc(-n3cccn3)cc2)s1 +CCOCCNC(=O)N1CCN(c2nc3ccccc3s2)CC1 +COCC1CCC2C(CCN2C(=O)c2ccc(C#N)cc2)O1 +COc1ccccc1NCC(=O)N1CCN(c2ncccn2)CC1 +CCn1c(C)cc(C(=O)CN2CCCC(NC(C)=O)C2)c1C +N#CC(CC(=O)Nc1ccccc1Cl)c1cccs1 +O=C(c1cn2cccnc2n1)N1CCC(Nc2ccccc2)C1 +COCCC(=O)NCCS(=O)(=O)N1CCNCC1 +O=C(Nc1nccs1)C1CCCN1C(=O)CCc1cccc(F)c1 +CCn1c(C)cc(C(=O)N2CCC3(CCCN(C(C)C)C3=O)C2)c1C +CC(=O)Nc1ccc(CC(=O)OCc2ccccc2Cl)cc1 +CCOC(=O)c1cc(NC(=O)c2cc(C)on2)cn1C +Cc1ccccc1CNc1ncc(C(N)=O)cc1Cl +COc1ccc(-c2nnc(NC(=O)c3cccc(F)c3)o2)cc1OC +CNC(=O)NCC(=O)NC1C2CC3CC(C2)CC1C3 +O=S(=O)(c1ccc(Cl)c(Cl)c1)n1ccnc1 +Cc1ccc(CNS(=O)(=O)N2CCOCC2)s1 +CCCn1c(SCC(=O)NCC(C)C)n[nH]c1=O +O=C(NCc1ccccc1)c1cccc2nscc12 +Brc1ccccc1NCc1nccs1 +CCS(=O)(=O)NCCNC(=O)c1ccc(C(C)(C)C)cc1 +CCc1ccccc1CNC(=O)NCCc1ccc(NC(C)=O)cc1 +CC(=O)Nc1ccc(F)c(NC(=O)Cc2ccccc2Cl)c1 +CC1COCCN1CC(=O)Nc1ccnn1Cc1cccs1 +N#Cc1ccccc1S(=O)(=O)NCc1ccccc1Cl +COc1ccc(-c2nnc3c4ccccc4ncn3c2=O)cc1 +Cc1nc2ccccn2c1C(=O)NCC(O)C1CCCCC1 +COc1ccc(C)cc1NCCC(=O)NCC1CCC1 +CC(C)(C)CC(=O)Nc1cccc(S(N)(=O)=O)c1 +COc1ccc(C(=O)NCc2cccc(C)n2)cc1 +COCCN(Cc1ccoc1)C(=O)c1ccccn1 +Cc1csc(=O)n1CCN1c2ccccc2CC1C +CCOCCNC(=O)C1CC(=O)N(C)C1c1cccc(Cl)c1 +CCc1nn2c(=O)cc(CNc3cccc(Cl)c3C)nc2s1 +CCc1cccc(C)c1NC(=O)C(CC(C)C)N1CCC1=O +CN(CC(=O)N1CCN(CCO)CC1)c1ccccc1 +COc1ccc(S(=O)(=O)CC(C)C#N)cc1Cl +CCOc1ccc(NC(=O)N2CCCC2C(C)(C)O)cc1C +CCc1noc(CC)c1CC(=O)NCC(=O)N1CCCC1 +O=C(NCCCOC1CCCC1)c1cc(Cl)c[nH]1 +C=C(C)CSc1nc2cc(S(N)(=O)=O)ccc2n1CCC +NC(=O)c1cccc(NC(=O)Cc2cc(F)cc3c2OCOC3)c1 +Cc1nnsc1C(=O)Nc1ccccc1Cc1nc(C2CC2)no1 +CCN(CC)S(=O)(=O)N1CCN(c2nc3ccccc3o2)CC1 +Cc1ccc(Cl)cc1NC(=O)c1ccc(N)cc1 +CC(C)(C)c1ccc(C(=O)N(CCC#N)Cc2cccnc2)cc1 +CCOc1c(Cl)cccc1NC(=O)C1CCC(=O)N1 +C#CCNC(=O)CNC(=O)Nc1ccccc1SCC(F)(F)F +Fc1cccc(-c2nnn(CCc3ccncc3)n2)c1 +CCSc1ccccc1C(=O)N1CCCC1c1nc(C2CC2)no1 +Cc1ccc(-n2[nH]c(C)c(-c3c(Cl)c(=O)c3=O)c2=O)cc1 +Cc1cc(C)n(-c2ccc(CNCc3c(F)cccc3F)cn2)n1 +CN(Cc1nc2ccccc2[nH]1)c1ccc(C#N)cn1 +COC(=O)C(C)N(c1cc(Cl)ccc1OC)S(C)(=O)=O +O=C(N1CCN(c2ccc(C(F)(F)F)cn2)CC1)n1ccnc1 +CC(NC(=O)c1ccccn1)C(=O)Nc1cccc(N2CCCC2)c1 +Cc1ccc(NC(=O)NCc2cccnc2)cc1C(N)=O +O=C(Cn1nc2c(cc1=O)CCCCC2)N1CCc2ccccc2C1 +Cc1cc(C)c2oc(=O)cc(CNC(=O)c3ccccc3F)c2c1 +COCc1nc2ccccc2n1CC(O)COc1cc(C)cc(C)c1 +COCc1cccc(C(=O)NCCCn2cccn2)c1 +COc1cccc(C(=O)Nc2cc(F)ccc2C)c1 +COCCn1c(-c2cnc(N3CCCC3)nc2)nc2ccccc21 +COc1ccc(C)cc1-c1nc2sc(C)nn2c1CO +O=C(Oc1ccc2c(c1)OCCO2)c1ccccc1-n1cccn1 +Cc1ccccc1C(C)CC(=O)N1CCN(C(=O)CO)CC1 +CC(=O)N1CCC(C(=O)NCCNC(=O)c2cccnc2)CC1 +Cc1cc(NC(=O)CN2CCCC(NS(C)(=O)=O)C2)on1 +CCc1nc(NCC2CCCO2)c(C#N)c2c1CCCC2 +Cn1ncc2c1ncn1nc(C3CCCN(S(C)(=O)=O)C3)nc21 +Cc1cc(C)c(C(=O)Nc2cccc(OCC(=O)N(C)C)c2)c(C)c1 +CC(C)Cn1c(N)c(-c2csc(NC3CC3)n2)c(=O)n(C)c1=O +CC(=O)c1c(C)[nH]c(-c2csc(NCC(C)C)n2)c1C +OC(CN1CCOCC1)(c1ccccc1)c1ccc(F)cc1 +Cc1noc(C)c1C(C)NC(=O)C(C)Sc1ccccc1 +Nc1ncccc1C1NCCc2c(F)cc(F)c(F)c21 +Nc1nonc1-c1nc(-c2c(O)cccc2O)cs1 +CCNC(=O)COC(=O)c1cc(-c2ccccc2)nn1-c1ccccc1 +Cc1oncc1C(=O)N1CCC2OCCCC2(COCC2CC2)C1 +Cc1cc(C)n(CC(C)CNS(=O)(=O)c2cc(C)oc2C)n1 +O=C(CSc1nnc(-c2cccnc2)o1)c1ccccc1F +COc1ccc(F)cc1NC(=O)c1ccc(Cl)cn1 +Cc1csc(SCC(=O)NCc2ccc(C)c(F)c2)n1 +CC(Oc1ccc(F)c(F)c1)C(=O)C(C#N)c1nc2ccccc2o1 +COC(=O)c1ccc(Cl)c(NC(=O)C2CC2C)c1 +COc1cccc(NC(=O)C2CC=CCC2C(=O)N2CCOCC2)c1 +CC(=O)Nc1ccc2c(c1)C(c1ccc(C#N)cc1)NCC2 +O=C(CNC1=NS(=O)(=O)c2ccccc21)NC1CCCNC1=O +CCOC(=O)C1CCN(C(=O)c2ccc(OC)cc2OC)CC1 +Cc1ccc(S(=O)(=O)NC(=O)Nc2ccc(F)cc2F)cc1 +CCCN(C)C(=O)c1cn2ccnc(-c3ccc(C)cc3)c2n1 +NC(=O)c1ccsc1NC(=O)CSc1nc2ccccc2[nH]1 +CC(C)n1nnc(S(=O)(=O)c2ccc(Cl)cc2)c1N +O=C1CCN(c2c(F)c(F)c(F)c(F)c2F)CC1 +COC(OC)(OC)C(C)(C)c1ccc(F)c(F)c1 +CCC(NC(=O)NCc1ncn(C)n1)c1ccc(F)cc1F +CC(Sc1ccccc1)C(=O)Nc1nnc(C2CC2)s1 +Fc1cc(Cl)c2c(c1)C(c1cncs1)NCC2 +CC(C)c1cc(C(=O)N2CCN(c3cnccn3)CC2)no1 +Cc1nc(-c2ccco2)ccc1C(=O)N(C)CC(=O)N1CCCC1 +CNC(CCSc1ccc2c(c1)CCC2)C(=O)OC +CNC(=O)CNC(=O)CSc1nc2ccccc2[nH]1 +Cc1n[nH]cc1CNC(=O)COc1ccc2c(c1)CCC2 +COCCN1CCN(C(=O)c2sc(C)cc2OC)CC1=O +COc1ccc(CNC(=O)N2c3ccccc3CC2C)c(OC)c1 +Cc1cc(F)ccc1CCNC(=O)CNC(=O)c1ccoc1C +CC(=O)NC(CC(=O)Nc1cc(F)ccc1F)c1ccccc1 +CCc1onc(C)c1NC(=O)NCC1(c2ccc(F)cc2)CC1 +O=C(NC(CO)CO)c1ncoc1-c1ccc(F)cc1 +O=C(c1ccco1)N1CCCC(c2nnc(-c3cccs3)o2)C1 +Cc1ccc(NC(=O)CN(c2ccccc2C)S(C)(=O)=O)nc1 +N#CC(NC(=O)Cc1coc(-c2cccs2)n1)c1ccsc1 +CCCNC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(OC)nn1 +CC(C)NC(=O)c1ccc(C(=O)NC2(C)Cc3ccccc3C2)cc1 +Cc1nc(CN(C)CC(=O)c2c(C)[nH]c3ccccc23)cs1 +O=C(NCc1c(F)c(F)cc(F)c1F)NC1(CO)CCCC1 +CC(C)n1c(C(=O)Nc2ccccn2)cc2sccc21 +COC(=O)C1=C(C)N(C)C(=O)N(C)C1c1ccccc1 +CCn1ccnc1S(=O)(=O)Cc1cccc(C#N)c1 +C#CCN(Cc1cccc(C)n1)Cc1ncn(-c2ccccc2)n1 +CCOCCNCc1cc(=O)c2cc(C)ccc2[nH]1 +NC(=O)Cc1cccc(OCc2ccc(Br)cc2F)c1 +Cc1cc(C(=O)N2CCN(Cc3cccc(F)c3)CC2)cs1 +COc1ccccc1N1CCN(Cc2cccc(C(N)=O)c2)CC1 +CC(C)CNC(=O)NC1CCN(c2ccccc2)CC1 +COc1ccc(NC(=O)C2CN(C(=O)c3cnccn3)C2)cc1 +COc1ccccc1C(=O)NCC(=O)NC1CCCC(C)C1 +O=C1CCN(C(=O)c2ccnc(OC3CCC3)c2)c2ccccc2N1 +CC(C)(C)OC(=O)N1CCCCC2CC(=O)CC21 +CS(=O)(=O)N1CCCCC1C(=O)N1CCc2ccccc2C1 +CCc1onc(C)c1NC(=O)N1CCC(C(=O)OC)CC1 +CCCn1cc(-c2cc(C(=O)N3CCCC3C)c3ccccc3n2)cn1 +COc1cccc(C(=O)Nc2ccn(CCC(N)=O)n2)c1F +Cc1c(C(C)NC(=O)C2CC(=O)N(C(C)C)C2)oc2ccccc12 +Cc1ccc(C(=O)N2CCN(C(=O)c3cnccn3)CC2)c(C)c1 +Cc1nc(N(C)C)sc1CNC1(C)Cc2ccccc2C1 +N#Cc1cccc(OCCCN2CCCCC2=O)c1 +CC(C)Oc1ccc(NC(=O)C2CCCNC2=O)cc1 +COc1ccc(C(=O)CSc2nc(=O)n3ccccc3n2)cc1 +CCC(C)N(Cc1ccncc1)C(=O)Cn1cc(C)c(=O)[nH]c1=O +CCCC(=O)N(C)Cc1nc(N2CCCC2)ncc1-c1ccncc1 +COC(=O)NCC(=O)Nc1nc(-c2ccccc2)ns1 +CC(=O)NCc1ccc(S(=O)(=O)N(C)CC(=O)NC2CC2)s1 +C=CCN(CC=C)C(=O)Cc1cn2ccsc2n1 +O=C(c1ccccc1F)N1CCC(Oc2cccnc2)CC1 +CNC(=O)c1cc(S(N)(=O)=O)ncc1OC1CC1 +Oc1ccc2cccc(NCc3ccncc3)c2c1 +CCc1nnc(-c2ccccc2OCC(=O)NCc2ccco2)o1 +O=C(C(c1ccccc1)n1cccn1)N1CCCC(n2cccn2)C1 +c1ccc(CCc2noc(-c3ccc(-c4ccc[nH]4)nc3)n2)cc1 +CCOc1ccc(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)cc1 +O=C(NCCc1n[nH]c(-c2ccc(Cl)cc2)n1)c1ccccc1 +Cc1cc(C)cc(OCC(=O)Nc2ccc3c(c2)NC(=O)CO3)c1 +COc1ccc(-n2nc(C(=O)NC(C)C)c(=O)cc2OC)cc1 +CCCN1CC(NC(=O)c2cc(C)nc3c(C)cc(C)cc23)CC1=O +CN(Cc1nc2ccccc2n1C)C(=O)c1scnc1C1CC1 +O=C(NCc1ccnc2ccccc12)N1CCOCC1C1CC1 +CCOc1ccccc1NC(=O)N1CCCC1c1cc(C)no1 +O=C(NCCSc1ccccc1F)NC1CC1 +CC(C)c1nc(-c2nc(CC(N)=O)nn2-c2ccccc2F)cs1 +O=C(CCc1nc(-c2ccncc2)no1)NCC1CC2C=CC1C2 +Cc1nc(NC(=O)NCc2cccc(Cl)c2)nn1C +O=C(NCC(=O)N1CCN(c2ccc(Cl)cc2)CC1)c1cc[nH]n1 +c1ccc(C2CN(Cc3cnc(N4CCOCC4)s3)CCO2)cc1 +O=C(CCc1ccccc1)N1CCCN(C(=O)C2CC=CC2)CC1 +CCC(=O)Oc1ccc(C(=O)Nc2ccccc2OC)cc1OC +CN(C)C(=O)CNc1cccc2c1CCN(S(C)(=O)=O)C2 +CC(C)(C)C(=O)N1CCC(C(=O)Nc2ccc(OCC#N)cc2)CC1 +Cc1ccc(C)c(C(=O)NCCNC(=O)c2ccco2)c1 +CC(C)N(CC(=O)NCc1ccccn1)c1ccc(N)cn1 +COc1cc(CN(C)C(=O)Nc2cnccc2C)ccc1SC +O=C(Nc1ccccn1)C1CN(C(=O)c2cccs2)C1 +CNC(=O)NC1CC2(CCN(C(C)=O)CC2)c2ccc(C)cc21 +CC(CC(=O)N1C(C)COCC1C)c1ccccc1F +CCOc1ccc(C(=O)N(C)Cc2ncnn2C)cc1 +O=C(c1cc2c(F)cccc2s1)N1CCOCC1 +Cn1nnnc1SCC(=O)N(CCC#N)c1ccc(F)cc1 +CC(=O)c1ccc(OS(=O)(=O)c2ccccc2Cl)cc1 +Cc1ccc(OCCNS(=O)(=O)Cc2ccon2)cc1 +CCOc1c(Cl)cc(CNC(=O)Nc2nncs2)cc1OC +CNC(=O)c1ccc(OC2CC2)cc1C(F)(F)F +C1=CCC(CNc2ccc(-n3cccn3)nc2)CC1 +CC(=O)Nc1ccc(NC(=O)Cn2nnc3ccccc3c2=O)cc1 +COc1cc2ccccc2cc1C(=O)N1CCN(C(=O)C2CC2)CC1 +Cc1ccc(-c2cnn3cc4c(nc23)CCCC4=O)cc1 +COC(=O)c1ccccc1NCC(=O)Nc1ccccc1C(C)=O +CCc1cc(C(=O)NCc2ccc(OC)c(OC)c2OC)sc1C +Cc1cccc(NC(=O)CSc2ncnc3nc(C)ncc23)c1 +Cc1ccccc1C1(CNC(=O)c2ccn(C)c(=O)c2)CCOCC1 +CNc1snc(C)c1C(=O)N1CCc2ccc(F)cc21 +O=C(CC1CCCC1)NCC1Cn2nnc(-c3ccsc3)c2CO1 +Cc1ccc(NC(=O)C2CCCN(Cc3sc(C)nc3C)C2)nc1 +Cc1cc2c(N3CCN(CCO)CC3)ncnc2s1 +CC(CO)N(C)c1cc(N(C)C(C)CO)ncn1 +Cc1cc(-c2nn3c(-c4cc(F)ccc4Cl)nnc3s2)n[nH]1 +O=C(OC1CCOC1)c1cccc(OCC(F)F)n1 +COc1ccc(-c2nnc(SCc3ccccn3)o2)cc1 +O=C1CCCN1c1cccc(NCc2ccccc2Br)c1 +Cc1n[nH]c2ncc(NC(=O)CC3(N4CCOCC4)CCCC3)cc12 +CC(O)(CNC(=O)c1cccc(-c2ccoc2)c1)c1ccco1 +CCc1cccc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)c1 +Cc1noc(C)c1CCC(=O)Nc1cccnc1N1CCCC1 +CC(C)c1noc(CCNC(=O)Nc2ccc3c(c2)CCC3)n1 +COc1ccc2c(c1)CN(S(=O)(=O)c1ccc(C(N)=O)cc1)CC2 +O=C(Nc1ccnc2ccnn12)c1ccc(F)nc1 +O=C(NCCc1ccccc1F)Nc1cccc(Cn2cccn2)c1 +CCNC(=O)CSc1nnc(COc2cc(C)ccc2C)o1 +CCOc1ccccc1CNC(=O)c1cnc2sccn2c1=O +O=S(=O)(Oc1c(F)c(F)c(F)c(F)c1F)c1nccs1 +Cn1cc(C#N)c(=O)n(CC(O)COCc2ccc(Cl)cc2)c1=O +CC(C)(C)c1cc(C(=O)NCCn2nc3ccccn3c2=O)[nH]n1 +CC(C)(C)c1noc(C(=O)c2cnn(-c3ccccc3)c2)n1 +Cn1c(N)c(NC(=O)c2ccco2)c(=O)n(C)c1=O +O=C(Nc1ccc2c(c1)COC2)c1[nH]ncc1Br +COCCOc1ncccc1NC(=O)c1csc(-c2ccco2)n1 +COc1ccc(NC(=O)NCCCC(N)=O)c(OC)c1 +CN(Cc1nccn1C)c1ncnc2c1cnn2-c1ccc(F)cc1 +C=CCCNC(C)(C(N)=O)c1cccc(Cl)c1 +Cc1cc(N2CCc3[nH]nc(C(C)C)c3C2)n2nc(C)c(C)c2n1 +O=C(C1COc2ccc(F)cc2C1)N1CCOC(C2CCCO2)C1 +CCOc1ccc(NC(=O)CCNC(=O)c2ccccc2)cc1 +CC(c1ccccc1Cl)N(C)C(=O)CN(C)S(C)(=O)=O +Cc1noc(-c2ccc(C(=O)NC3C4CCOC4C3(C)C)cc2)n1 +CCn1c(C(=O)Nc2c(C)noc2C)cc2sccc21 +Oc1ccc(Cl)cc1-c1cc(-c2ccco2)[nH]n1 +N#CC1(C(=O)N2CC3CC4CC(C3)CC2C4)CCCC1 +COC1CCCC(OC(=O)Cn2cc(Br)ccc2=O)C1 +CC(C)c1cc(NC(=O)N2CCC(Oc3cccnc3)C2)no1 +Cc1noc(C2CCCN2C(=O)Cn2cnc3ccccc32)n1 +CS(=O)(=O)NCC(=O)Nc1ccccc1COc1ccccc1 +O=C1CCN(Cc2cnn(-c3ccccc3)c2)CC1 +N#Cc1ccc(-c2noc(C3(c4ccccc4)CC3)n2)nc1 +CCNC(=O)c1cccc(NC(=O)CSc2nncn2C)c1 +Cc1cc(NC(=O)C(C)Oc2ccccc2C)no1 +Nc1nc(N2CCN(c3ccccc3)CC2)c2nc[nH]c2n1 +C=CCN(Cc1ccc(OC)cc1)C(=O)C1(C#N)CCCC1 +COC(=O)Nc1ccc(CNC(=O)c2sc(C)nc2C)cc1 +c1ccc(COc2ccccc2NCCN2CCOCC2)cc1 +CC(=O)Nc1ccc(-c2ccc(NC(C)=O)c(C)c2)cc1C +CC1(C)CC(=O)c2c(O)cc(OCC(=O)NC3CCCC3)cc2O1 +COCCN(CC(F)(F)F)C(=O)C1CC1c1ccccc1 +Cn1c(C(=O)NCC(=O)Nc2cccnc2)cc2occc21 +O=c1cccnn1CCNS(=O)(=O)c1cccnc1 +Cc1cc(C)c(C(N)=O)c(-c2cccc3ccsc23)n1 +CCCc1cc(C(=O)N=c2sccn2C)[nH]n1 +COc1ccc(-c2cc(CO)c(=O)n(C)n2)cc1C +COC(=O)C(Nc1nc(C2CCCC2)nc2c1cnn2C)C(C)O +CCOC(=O)c1cnn(-c2nc(OC)cc(OC)n2)c1C(F)(F)F +COCCn1c(CNC(=O)c2cccs2)nc2ccccc21 +CC1CN(CC(O)Cn2nc(-c3ccccc3)oc2=O)CC(C)O1 +CCC1CCCN(C(=O)c2cn(-c3ccccc3)nn2)C1 +Nc1nnc(SCC(=O)c2ccc3[nH]c(=O)[nH]c3c2)[nH]1 +COc1ccc(C(C#N)Cc2ccccn2)cc1C +Cc1ccc(NC(=O)N(CCC#N)CC(C)C)cc1 +Cc1nc(N)cn1-c1cccc(Br)c1 +Cn1nc2n(c1=O)CCN(S(=O)(=O)c1ccc(F)c(F)c1F)C2 +CN(C)c1ccc2c(c1)S(=O)(=O)N=C(NC(C)(C)CO)N2 +CCCCn1c(N)c(NCC2CCCOC2)c(=O)[nH]c1=O +COc1ccc(C(=O)N2CCCC(CNS(C)(=O)=O)C2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)NC1CC1C1CCCCC1 +COCC1CCCN1C(=O)Cc1cnc2c(C)cccn12 +CN(Cc1ccc(C#N)cc1)C(=O)NCc1ccnn1C +Cc1ccsc1C(=O)N(CCO)C1CCCCC1 +Cc1cccc(NC(=O)c2cc(C(F)(F)F)n[nH]2)c1C +Cc1nc(C)c(C(C)N(C)Cc2cccc(-c3ccncc3)c2)s1 +COc1ccc2ncnc(N3CCCCC3C)c2c1 +Cc1cc(C)c(CNC(=O)c2n[nH]c(=O)c3ccccc23)c(=O)[nH]1 +COC(=O)c1c(C)[nH]c(C(=O)OCC(=O)NC2CCCCC2)c1C +O=S(=O)(c1ccccc1F)N(Cc1cccnc1)Cc1ccco1 +CC(C)S(=O)(=O)c1ccc(-c2cnc(N)o2)cc1 +COCCCCNc1ccc(C(=O)N2CCCCC2)c(Cl)c1 +COCCCNc1ncc(-c2ccccn2)c(-c2cccs2)n1 +CCOC(=O)N1CCN(CC(=O)NC2CCCCNC2=O)CC1 +CCCCCNC(=O)C(C)Sc1nc(N)c(C#N)cc1C#N +COCCOC1CCN(C(=O)c2oc3c(F)cccc3c2C)CC1 +Cc1cc(=O)oc2cc(OC(=O)CNC(=O)OC(C)(C)C)ccc12 +CCc1onc(C)c1NC(=O)CC1(N2CCOCC2)CCCC1 +COCCOCC1NCCc2ccc(OC)c(F)c21 +CCOc1ccccc1OCC(=O)Nc1c(C)cccc1CC +O=C1CCC2C(CCN2C(=O)N2CCCC2)N1Cc1ccncc1 +CCOc1cccc(C(C)NC(C)C(=O)Nc2cc(C)no2)c1 +O=S(=O)(NCc1cccc(CO)c1)c1cccs1 +c1nc2c3c4c(sc3nc(N3CCCCC3)n2n1)CCC4 +O=C(c1csc(S(=O)(=O)N2CCOCC2)c1)N1CCCCC1 +CCN(CCc1ccccc1)C(=O)c1cccc(N2CCCC2=O)c1 +O=C(Oc1ccc(N2CCOC2=O)cc1)C1CC2CCC1C2 +O=C1NCC(=O)N2CCN(C(=O)c3cccc(-c4cn[nH]c4)c3)CC12 +CNC(=O)Oc1ccc(C(=O)c2ccc(O)cc2)cc1 +COc1ccc(OCc2cccc(C(=O)N3CCCCC3)c2)cc1 +CN1CCc2nc(C(=O)c3ccncc3)sc2C1 +O=C(NCCc1cccs1)NCc1cccc(O)c1 +CCc1cc(C(=O)N(CC)Cc2ccccc2C)[nH]n1 +NS(=O)(=O)c1cnn(CCCOc2ccccc2)c1 +COc1ccc(CC(=O)NCc2ccc(N3CCCC3=O)cc2)cc1 +O=C(Nc1n[nH]c(CCc2ccccc2)n1)c1cccc2[nH]ccc12 +O=S(=O)(Cc1ccccc1F)c1ccc(Br)cc1 +c1ccc2nc(N3CCCC3)c(N3CCCC3)nc2c1 +O=S(=O)(NCC1Cn2ccnc2CO1)c1ccccc1 +Cc1cccn2c(=O)c3cc(C#N)c(=O)n(Cc4ccco4)c3nc12 +Cc1ccc(CN(C)C(=O)c2cc(-c3cnn(C)c3C)[nH]n2)o1 +COCc1ncc(C(=O)N2CC(C)CC(C)C2)c(N)n1 +CC(C)(C)NC(=O)Nc1cccc(OCC(=O)N2CCCC2)c1 +COc1ccc(CNC(=O)C(C)n2c(=O)oc3ccccc32)cc1 +CCNC(=O)N1CCN(C(=O)C2CCCC2)CC1 +COCc1ccc(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)cc1 +Cc1cc(Cl)ccc1OCCCNC(=O)NCc1cccnc1 +CCc1noc(CC)c1CC(=O)Nc1cc(C)ccc1F +CCN1CCc2nc(NC(=O)c3ccc4c(c3)OCCO4)sc2C1 +CC(=O)Nc1ccccc1NC(=O)C(C)Oc1ccccc1 +CC(C)c1nc2ccc(F)c(F)c2n1-c1ccncc1 +CC(C)c1cc(NCC2(Cn3cccn3)CC2)n2nccc2n1 +CCC(=O)NCC(=O)Nc1ccnn1Cc1ccc(Cl)c(F)c1 +CC(C)NC(=O)C(C)NC(=O)c1n[nH]c2ccccc12 +COc1ccc(-c2nccn2Cc2cccc(C#N)c2)cc1 +O=c1[nH]c(NCc2ccccc2Cl)nc2c1CCC2 +Cc1ccccc1COC1CCN(C(=O)CCCn2cncn2)CC1 +Cc1ccnc(NC(=O)c2cc(CC(C)C)n[nH]2)c1 +CCCC(=O)Nc1cccc(NC(=O)C2CCCN2C(=O)C2CC2)c1 +CCOC(=O)Nc1nc2c(s1)CN(C(=O)C1CCC1)CC2 +Cc1csc(NC(=O)c2ccc3c(c2)OCO3)n1 +Cn1cccc1CNC(=O)c1ccc2nnnn2c1 +CCC1C(=O)NCCN1C(=O)CCSc1ccc(OC)cc1 +O=C(Nc1cccc(F)c1)N1CCN(Cc2cccc(O)c2)CC1 +Cc1cc2ccccc2n1CC(=O)NCc1nnc2ccccn12 +CNC(=O)c1sc(-c2cccc(NC(=O)C3CC3)c2)nc1C +CCn1ncc(-c2cc(C(F)(F)F)c3cnn(CC)c3n2)c1C +Cc1ccc(NC(=O)Nc2nnc(N3CCCC3)s2)c(C)c1 +CCCNC(=O)c1cccc(C(=O)N(C)CCOC)c1 +Cc1ccccc1C(=O)Nc1ccccc1C(=O)NCC(F)(F)F +CCc1ccsc1C(=O)NC1CCN(S(C)(=O)=O)CC1 +COCC(NC(=O)c1ccc(F)c(F)c1F)C(N)=O +CCCn1nc(C(=O)N2CCN(Cc3cccs3)CC2)ccc1=O +CC(Oc1cccnc1)C(=O)Nc1cc(Cl)c(O)c(Cl)c1 +Cc1nc(NCC2CC(=O)N(C(C)C)C2)c2cnn(C)c2n1 +CCCn1cnnc1Cn1ccnc1-c1cc(C)ccc1-n1cccn1 +Cn1cc(C2CC2C(=O)OCCN2CCCCCC2=O)cn1 +N#CCn1cnc2c(nnn2-c2ccc(Cl)cc2)c1=O +CC1CCN(C(=O)CCCNC(=O)OC(C)(C)C)C(C)C1 +C=CCNC(=O)c1ccccc1NCc1noc(C)n1 +CCn1cc(NC(=O)c2csc(-c3ccco3)n2)ccc1=O +Cc1ccccc1C(=O)NCCC1=CCN(Cc2cnc[nH]2)CC1 +Cc1ccc(SCCC(=O)Nc2ccccc2S(C)(=O)=O)cc1 +CC(=O)Nc1ccc(NC(=O)CCCNC(=O)c2cccs2)cc1 +COC(CNC(=O)c1ccc(-n2ccnn2)cc1)C(C)(C)C +CC1=C(c2ccccc2)S(=O)(=O)N=C1N1CCc2ccccc2C1 +Cc1nccc(NC(=O)c2ccc(F)cc2F)c1Cl +COc1ccc(CNC(=O)c2cccc(-n3cccn3)c2)c(F)c1F +CCC(CC)N(CCO)C(=O)c1ccc(F)c(F)c1 +CC(C)NC(=O)COC(=O)c1csc(-c2cccs2)n1 +CN(CC1CC1)C(=O)c1cc(Cl)cc2cccnc12 +Cn1nnnc1SCc1ccc(CSc2nnnn2C)cc1 +CC(C)Cn1ccn(-c2ccc(Cl)cc2)c(=O)c1=O +CC(C)Cc1ccc(C(=O)CN2CCOCC2)cc1 +COCc1cccc(NC(=O)Cn2ccc(N)n2)c1 +Cc1ccc2[nH]nc(C(=O)NCc3nnc4n3CCCCC4)c2c1 +CC(=O)Nc1cccc(NC(=O)c2cccc(Cl)c2)c1 +COc1ccccc1CNC(=O)CCn1ncc2ccc(C)cc21 +OCCc1csc(CCc2cccc(Cl)c2)n1 +CC(C)(C)NC(=O)c1nccc2c(N)c(Cl)ccc12 +Cc1noc(C)c1CC(=O)NC(C)Cc1cccc(Cl)c1 +O=C(OCC1CC1)c1ccc(OCC(F)(F)F)nc1 +COC(=O)CC(NC(=O)Nc1ccc(F)cc1F)c1cccs1 +CC(C)(CO)NC(=O)c1ccc2nc(-n3cccc3)sc2c1 +CSc1nc(=O)[nH]c(C)c1C(=O)NCC(C)O +CCN1CCN(C(=O)C(C)Oc2ccc(-c3nnco3)cc2)CC1 +Cc1noc(CCCC(=O)N2CCCC(c3cc(C)[nH]n3)C2)n1 +CC1CN(C(=O)Cn2nnnc2C(C)C)CC(C)O1 +CCc1ncc2c(n1)CN(C(=O)c1snnc1CC)C2 +CC(NC(=O)c1cccc(OCC(F)F)n1)C1CCOCC1 +COc1ccc(-c2cc(COC(=O)c3cnccn3)no2)cc1 +CNC(=O)COC(=O)c1ccn(-c2ccc(F)cc2)n1 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccn(-c2ccccc2)n1 +CSc1cccc(NC(=O)CSc2nccc(=O)[nH]2)c1 +CCOc1ccc(C2CC(=O)c3cc(C)cc(N)c3O2)cc1 +CC(=O)c1c(C)nc(C)nc1SCC(=O)NCc1ccccc1F +O=C(CCCc1ccc(Cl)cc1)N1CCC(c2nc[nH]n2)CC1 +C#CCN1CCC(C(=O)Nc2c(CC)cccc2CC)CC1 +Cc1cccc(C)c1OCCNCc1cncnc1 +CCn1cc(C(=O)N2CCC(c3ccc4ccccc4c3)C(O)C2)cn1 +c1cnc2nc(SCc3csc(-c4ccoc4)n3)nn2c1 +COc1cccc(CNC(=O)COc2nnc3ccccn23)c1 +C=CCN(CC=C)C(=O)C1CC(=O)N(c2ccc(C)cc2C)C1 +Cc1ccc(N2CCCN(Cc3cn(C)nc3C)CC2)nn1 +C#CCNCc1cc(Br)ccc1OCCC +CCCN(C(=O)c1cc(Cl)ccc1N)C(C)C +COCCNC(=O)N(Cc1ccc(OC)cc1)C1CC1 +O=C(NCc1cn(-c2ccccc2)nn1)c1cnc2ccccn2c1=O +Cc1onc(-c2ccccc2)c1C(=O)NCc1cnn(C)c1 +O=C(NCc1ccccc1Cl)N1CCCCC1CCO +CCc1nnc(C2CCN(C(=O)Nc3cccc(OC)c3)CC2)s1 +COc1ccc(COC(=O)C(N)c2ccccc2)c(OC)c1 +Cc1nccn1-c1ncccc1NC(=O)C1CC1c1ccccc1F +Cc1c(F)cccc1NC(=O)N1CCNC(=O)C1C(C)C +CC(O)CNC(=O)CNC(=O)Cc1cccc2ccccc12 +CC(=O)NCCOc1ccccc1-c1ccccc1 +Cc1ccc(-c2cc(C(=O)N3CCNC(=O)C3)on2)cc1 +COC1CC(C)(O)C(OC(=O)CC(C)C)C(C)O1 +CC(C)Oc1ncccc1NC(=O)c1cccc(-c2ncn[nH]2)c1 +Cc1nc(CN(C)CCOc2cccc(Cl)c2)cs1 +CCc1ccccc1OC1CN(C(=O)c2cccc(F)c2)C1 +COC(=O)C(C)(NCC1CCCO1)c1cccnc1 +CCC(=O)N1CCCC(C(=O)OCc2ccccc2F)C1 +Cc1cccc(OCC(O)CNC(=O)Cc2ccccc2C)c1 +CCOC(=O)c1csc(NC(=O)c2ccc(SC)cc2)n1 +Cc1ccc(-n2nnnc2N(C)Cc2cccs2)cc1 +CS(=O)(=O)N1CCCCC1C(=O)Nc1cccc2cccnc12 +Cn1ncc2c(=O)n(CC(=O)c3ccccc3)cnc21 +Cc1csc(NC(=O)NCc2cnn(-c3ccccc3)c2)n1 +COc1nc(C(=O)N(C)CC(=O)NC(C)(C)C)cc2ccccc12 +COc1ccccc1CNC(=O)c1cc(CC(C)C)[nH]c(=O)c1 +CC(=O)c1ccc(C#CCNC(=O)C(C)Oc2ccccc2)cc1 +CCOC(=O)N1CCc2n[nH]c(C(F)(F)F)c2C1 +CN(C)C(=O)c1ccccc1NCC(=O)NCc1ccccc1 +CCN(C(=O)Cc1ccc(C)nc1)C(C)c1cc2ccccc2o1 +COc1c(C)cnc(CNC(=O)CCC(C)C)c1C +CC(O)(CNCc1ccc(F)cc1)c1ccccc1 +Cc1cc(C)cc(OCc2ccc(C(=O)Nc3nc[nH]n3)cc2)c1 +CCNC1=NS(=O)(=O)c2cc(OC)ccc2N1 +O=C(CCC(=O)N1CCCC1c1ccccn1)c1ccc(F)cc1 +Cc1nc(NC(=O)C2CC(=O)N(C3CC3)C2)sc1-c1ccccn1 +COc1ccc(NC(=O)C(C)Sc2nnc3n2CCCCC3)cc1 +COCC(O)CN(C)C(=O)c1c(C)cc(C)cc1C +Cn1c(=O)nc2n(-c3ccc(F)cc3)c3ccccc3cc-2c1=O +Cc1ccc(-c2nc(CN3CCc4cncnc4C3)cs2)cc1 +CC(OC(=O)C1CCCN1C(=O)c1ccco1)c1cccnc1 +Cc1ccc2nc(COc3ccc(S(C)(=O)=O)cc3)cc(=O)n2c1 +COc1ccc(-n2cc(CNC(=O)C#Cc3ccccc3)nn2)cc1 +CC(=O)N(C)c1ccc(NC(=O)OC(C)(C)C)cc1 +CCn1ccc2ccc(NC(=O)N(C)CCOCC3CC3)cc21 +COc1ccc(C(C)NC(=O)c2cc(C)on2)cc1F +Cc1noc(C)c1CCCNC(=O)c1ccc(N(C)C(C)C)nc1 +CCCc1ccc(C(=O)CCCC(=O)N(C)C)cc1 +CCOC(C(O)CO)n1cnc2c(N)ncnc21 +O=C(Cc1ccccc1)NCC(O)c1ccc2c(c1)OCCO2 +CCOc1ccc(CN(C)C(=O)Cc2nc3ncccn3n2)cc1 +Cc1onc(N)c1S(=O)(=O)N1CCN(c2ccccn2)CC1 +O=C1OCCN1CCSc1nnc(NC2CC2)s1 +C=CCNS(=O)(=O)c1ccc(Cl)c(OC)c1 +Cc1cncnc1C1CCCN(C(=O)c2cccnc2)C1 +COC(=O)CC(NC(=O)c1cccc(F)c1)c1ccc(F)cc1 +CCOc1cc(C(=O)N(C)C(C)C)ccc1OC +Cc1cnc(C(=O)Nc2ccc(Cl)c(C#N)c2)cn1 +CC(C(=O)NCc1ccc2c(c1)OCO2)n1cncn1 +COc1ccccc1C(=O)NCC#Cc1ccc(C(=O)N(C)C)cc1 +CC(NC(=O)NCc1ccncc1)c1ccc(N2CCCC2=O)cc1 +NC(=O)c1cccc(CNC(=O)N2CCOCC2C2CC2)c1 +CCNC(=O)c1ccc(NC(=O)COCC)c(C)c1 +NC(=O)c1ccccc1N1CCc2c(N)cccc2C1 +Cn1ncc2c(Oc3ccc(F)c(F)c3)ncnc21 +CC(=O)c1cn(-c2ncc(C(F)(F)F)cc2Cl)c(C)n1 +CC(C)S(=O)(=O)N1CC(c2ccnc(N)n2)C1 +CCc1ncc(C(=O)NCc2nc(C3CCCCC3)no2)cn1 +Nc1cccc(C(O)CCC(=O)NCC2CCCO2)c1 +CC(=O)Nc1cc(NC(=O)C(C)CC2CCCC2)ccc1F +Cc1ncc(CNC(=O)NCCc2ccccc2F)s1 +O=C(NCCC1CN(C2CCOCC2)CCO1)c1ccc[nH]1 +O=C1CCSc2c1cccc2C(=O)NC1CCCC1 +COCCN(C)S(=O)(=O)c1cccc(C(=O)N(C)C)c1 +CN1C(=O)Cc2cc(S(=O)(=O)NC(C)(C)CO)ccc21 +COc1cc(C)c(C)cc1S(=O)(=O)NC(C)CO +CCc1n[nH]c(C2CN(C(=O)C3CCOC3)CCO2)n1 +Cc1c(Cl)cccc1-n1c(C)c(C)c(C#N)c1N +COc1ccc(C2CC(O)=Nc3c2cnn3C(C)C)c(OC)c1 +COc1ccc(-c2noc(C(C)NC(=O)C(C)(C)C)n2)cn1 +Cc1cc(Cl)ccc1OC(=O)CNC(=O)c1cccs1 +Clc1cccc(-c2nnc(CN3CCOCC3C3CC3)o2)c1 +CCN1C(=O)C(C)Oc2c(OC)cc(CO)cc21 +CC1CN(C(=O)Cc2csc(-c3cccnc3)n2)CC(C)O1 +Cc1ccsc1CNC(=O)CN(C)c1cnccn1 +COCCn1cc(NS(=O)(=O)c2ccccc2)cn1 +O=C(CCOc1ccccc1F)N1CCCC(n2cncn2)C1 +O=C(Nc1cc(-c2ccccc2)n[nH]1)c1ccccc1 +CC1CN(c2ccc(S(C)(=O)=O)cc2S(C)(=O)=O)CC(C)O1 +CN1CCN(C(=O)C2CCN(c3ccccc3)CC2)CC1 +O=C1OCC2=C1C(c1ccc(Cl)cc1)c1cc3c(cc1O2)OCO3 +CC1CC1C(=O)Nc1ccc(S(N)(=O)=O)cc1F +CCCc1noc(-c2cccc(CNc3cc(C)nc4ncnn34)c2)n1 +CC(C)S(=O)(=O)c1ccc(C(=O)Nc2ccc(F)cc2)cc1 +Cn1ccc(CC(=O)NCC2CCN(c3cnn(C)c(=O)c3)CC2)c1 +CSc1ccccc1C(=O)NCCc1ccccn1 +Cc1nn(C)c2nc(C(C)C)cc(C(=O)NCC3CCC3)c12 +CCCC(C)NC(=O)CNC(=O)c1ccsc1 +O=C(CNC(=O)c1cccc(F)c1)NCC(=O)c1cccs1 +Nc1ccc(-c2nc(-c3c(F)cccc3Cl)n[nH]2)cc1 +CCOc1ccc(C(=O)C(C)NCC2CCCO2)cc1N +COC(=O)c1ccc(CNc2ccccc2C#N)cc1 +Oc1cccc(CNc2ccc(Br)cc2)c1 +O=C(c1ccco1)N1CCN(C(=O)C2C3CC4CC(C3)CC2C4)CC1 +NC(=O)c1ccc(NC(=O)CSc2nnnn2C2CCCC2)cc1 +CCOc1ccc(C(C)NC(=O)C2CCC2)cc1OC +Cc1nsc(N2CCN(C(=O)Cc3ccc[nH]3)CC2)n1 +CCOc1ncnc(N2CCc3ccccc3C2)c1N +Cc1ccc(-c2nc3ncc(C(=O)Nc4ccccc4)c(C)n3n2)cc1 +Cc1ccc(C)c(S(=O)(=O)CCCOCC(F)(F)F)c1 +Cc1cc(C)nc(-n2ncc(C#N)c2NS(C)(=O)=O)n1 +N#Cc1ccccc1NC(=O)c1ccc2c(c1)OCCO2 +CCC1(CC)Oc2cccc(N)c2N(CC(O)CO)C1=O +CCC1CCC(NC(=O)COc2cccc(NC(=O)C3CC3)c2)CC1 +CC(=O)c1cccc(OCC(O)Cn2nnc(-c3ccccc3)n2)c1 +COc1cc(OC)c2[nH]c(C(=O)OCC(=O)NC3CC3)cc2c1 +CCOc1ccc(C(NC(=O)c2nccnc2N)c2ccccc2)cc1 +COc1ccc(OCCN(C)C(=O)c2cccc(OC)c2F)cc1 +Cc1ccc(NC(=O)COc2ccccc2C#N)cc1 +COc1ccc(CNc2cnn(-c3ncccn3)c2)c2ccccc12 +CC(C)CC(=O)NCC(=O)c1ccc2c(c1)CCCC2 +CN(Cc1cc(-c2cccnc2)no1)CC(C)(C)N1CCOCC1 +CC(O)CN(C)S(=O)(=O)Cc1ccc(Cl)cc1Cl +O=C(COc1ccc2c(c1)CCC2)N1CCCCCC1 +CCNC(=O)CN1CCN(c2ncccc2C(N)=O)CC1 +CC(O)CN(C(=O)COc1ccccc1)C(C)(C)CO +CCc1ncc(C(=O)Nc2c3c(nn2C)CCC3)s1 +C#CCNC(=O)C(C)Nc1ccc2[nH]c(=O)[nH]c2c1 +Cc1csc(NC(=O)C2CC(=O)N(Cc3ccccc3)C2)n1 +COc1ccc(-c2cc(C(=O)Nc3ccccc3C#N)n[nH]2)c(OC)c1 +CCOC(=O)Cc1cc(=O)c2c(C)nn(-c3ccc(OC)cc3)c2[nH]1 +O=C(Nc1ccc(N2CCOCC2)cn1)c1cn2cccnc2n1 +CCN(CC)C(=O)COc1ccccc1C(=O)Nc1ccccc1 +CC1CN(C(=O)c2ccc(Cn3cccn3)cc2)c2ccccc21 +CCCCNC(=O)NCCc1ccc(S(N)(=O)=O)s1 +CCc1nnc(NC(=O)CNS(=O)(=O)c2ccccc2)s1 +CC(=O)N1CCCC(C(=O)NCc2nc(-c3ncccn3)no2)C1 +Cc1nn(C)c(C)c1C(=O)N1CCC(OCc2ccc(F)cc2)CC1 +Cc1ccc(C)c(Nc2nc(NCCO)nc3nccnc23)c1 +CNC(=O)COc1ccccc1CNc1ccc2c(c1)CCC(=O)N2 +COC(=O)c1ccc(COC(=O)c2cc(=O)[nH]c3ccccc23)o1 +CCn1c(=O)n(CC(O)c2ccc(F)cc2)c2ccccc21 +Cc1nnc(SCC(=O)N2C(C)CCCC2C)n1-c1ccccc1 +O=C(Nc1ccccc1)C1CCCN1C(=O)CCc1cccs1 +CCC(=O)N1CCN(c2ccc(C(F)(F)F)cc2N)CC1 +Cc1nc(CC(=O)N(C)Cc2ccccc2Br)cs1 +CC(C)CC(=O)Nc1ccc(N2CCN(C(C)(C)CO)CC2)nc1 +Cc1nc(-c2cccc(Br)c2)ccc1C(=O)N(C)C +Oc1cc2c(cc1F)CCNC2c1ccc(O)c(Cl)c1 +CC(C)(C)C(=O)Nc1ccc(N2CCCCC2=O)cc1 +Cc1ccc(C(O)CNC(=O)c2ccc(C#N)cc2)o1 +COCCNc1ncnc(Nc2ccc(Cl)cc2Cl)c1N +CCN(CC)C(=O)n1sc2ncccc2c1=O +Cc1ncc(Cl)c(C(=O)Nc2ccc(-n3cncn3)c(F)c2)n1 +CC(C)c1cc(=O)n(CC(=O)Nc2cc(Cl)ccc2C#N)cn1 +c1ccc2sc(N=C3NCN(CCN4CCOCC4)CN3)nc2c1 +CC1CC1C(=O)Nc1ccc(C(=O)N(C)C2CC2)cc1 +COCc1cccc(C(=O)N2CCC(C(=O)N3CCOCC3)CC2)c1 +CCNc1nc(Cc2nc(C)cs2)nc(C)c1CC +Cc1ccc(S(=O)(=O)N2CC(C)OC(C)C2)s1 +COc1ccc(F)cc1NC(=O)c1cnn(C(C)C)c1C1CC1 +O=C(NCCOc1cccc(F)c1)c1ccc2cc[nH]c2c1 +O=C(NCCNc1nc2ccccc2s1)c1ccc2[nH]cnc2c1 +COc1ccc(CNC(=O)CSc2nccc3ccccc23)cc1 +CCN(CC)C(=O)CCCC(=O)Nc1ccc(Cl)cc1F +Nc1ccccc1Cn1ccnc1Cc1ccc(F)c(F)c1 +Cc1ccc(OC(C)c2nc(-c3cccnc3)no2)cc1 +Cc1cc(C)c(NC(=O)Cc2cccc(F)c2)c(C)c1 +CCn1c(-c2ccccc2)nnc1S(=O)(=O)Cc1ccon1 +CC(O)C1CCN(C(=O)NC2CCC(C)(C)CC2)C1 +c1ccc(CN2CCN(Cc3nnc4n3CCCCC4)CC2)nc1 +O=C(Nc1ccccc1Cn1cccn1)c1ccc(F)cc1F +CC(NC(=O)Cn1c(=O)n(C)c2ccccc21)c1ccc(F)c(F)c1 +COc1ccc(C(C)C)cc1C(=O)NCCCO +CC(C)n1ccc(C(=O)N2CCN(S(C)(=O)=O)CC2)n1 +Cc1ccc(NC(=O)c2cn3nc(C)sc3n2)cc1 +CC1Oc2ccc(CCn3cc(N)cn3)cc2N(C)C1=O +OC(CN1CCN(c2ncccn2)CC1)c1ccccc1Cl +COc1ccnc2c1ccn2S(=O)(=O)c1ccccc1 +CC1CN(Cc2ccccc2)CCN1C(=O)c1cccc(N(C)C)c1 +Cc1nn(CCCC#N)c(=O)c2cc3sccc3n12 +COc1cc(CNC(=O)NCCOc2cccc(F)c2)ccn1 +COc1cc(C)ccc1NC(=O)NCc1ncc(C)c(OC)c1C +O=C(OCCOc1ccc(Cl)cc1Cl)c1cnccn1 +CCCn1ncc(C(=O)N2CCC(O)(c3ccccc3C)C2)c1C +Cc1nn(C(=O)Oc2ccccc2)c(C)c1Br +O=C(c1ccccc1O)N1CCCC(C2OCCO2)C1 +Cn1nc(C(=O)NCCc2ccncc2)c2ccccc2c1=O +O=C(COC1CCCCC1)c1ccc2c(c1)OCO2 +COc1ccc(CN(C)C(=O)c2ccn(C)c(=O)c2)cc1 +CC1CCCN(c2ncnc(Nc3cccc4ncccc34)c2N)C1 +CC(C)(C)C(O)CCNC(=O)c1c(F)cccc1Cl +Cc1c(C(N)=O)sc2ncn(CC(=O)N3CCCC3)c(=O)c12 +CCCc1cc(C2CCCN2C(=O)NCC(=O)OC)no1 +O=C(Nc1cnn(CC2CCCO2)c1)C1CC(=O)N(CC2CC2)C1 +CNC(=O)c1cc(NC(=O)NCC(C)(O)CCC(C)C)ccc1F +CSc1ccc(OC(=O)C2CCCN2C(=O)c2cccs2)cc1 +COCC1CN(Cc2ccncc2)Cc2nnn(C)c21 +COc1ccc(-c2nc(C)nc(C)c2N)cc1C(C)C +CCN(C)C(=O)c1cccc(OC(=O)CCn2cc(C)cn2)c1 +CCCn1nc(C)c(CN2CCOC(c3cccc(O)c3)C2)c1C +CC(Sc1nnnn1Cc1ccco1)C(=O)Nc1ncccn1 +Cc1ccccc1C(C)NC(=O)C(C)N1CCn2c(nn(C)c2=O)C1 +CN(C)c1cc(C(=O)NCCN2CCOCC2)nc2ccnn12 +COc1cc(C)ccc1OCC(=O)NCCCO +O=C(NCC1(c2cccs2)CC1)c1cnccn1 +COCCN(C)C(=O)CNS(=O)(=O)c1cccs1 +CC1CN(C2CCN(Cc3ccc(Cl)c(F)c3)CC2)CCO1 +Cc1cc(C(=O)N2CCN(C3CCCC3O)CC2)no1 +O=C1CCCN1c1ccc(OCc2ccc3c(c2)OCO3)cc1 +C#CCOC(=O)c1cc(Br)c(OCC)c(OC)c1 +Cc1cccc(NCC(=O)N2CC(C)CC(C)C2)c1 +COCC(=O)Nc1ccc(C(O)C2COCC(=O)N2C)cc1 +CCc1nc2c(s1)C(N(C)C(=O)NCc1ncn(C)n1)CCC2 +COCCCC(=O)N(Cc1ccc(C#N)cc1)C(C)C +CNC(=O)Cn1cc(CO)c2cc(Cl)ccc21 +Cc1nc(N2CCOC(Cn3cncn3)C2)c2c(C)c(C)sc2n1 +CN(C)C(=O)c1cccc(NC(=O)C2CC=CCC2)c1 +N#CCCCOc1cccnc1NC(=O)c1ccc2c(c1)OCO2 +CC1CC1CNC(=O)NCc1ccc(OC(F)F)cc1 +O=C(C1CCCC1)N1CCN(Cc2noc3ccccc23)CC1 +CCCCn1nc(C(=O)N(C)Cc2ccc(F)cc2)ccc1=O +CCOC(=O)c1ccc2[nH]c(NCC(F)(F)F)nc2c1 +CCN(Cc1ccoc1)C(=O)NCc1ccnc(OC(C)(C)C)c1 +CCCn1nc(C(=O)N2CC(c3ccc(F)cc3)CC2C)ccc1=O +COc1ccc(NCc2ccc(OC)c(O)c2)cn1 +Nn1c(SCCn2cccn2)nnc1-c1ccccc1Cl +COC(=O)C(C)OC(=O)CCc1nc2ccccc2c(=O)[nH]1 +COc1nc(CC(C)C)nc(NCc2ccccc2)c1N +O=C1CN(c2ncnc3sc4c(c23)CCCCC4)CCN1 +O=C(c1c[nH]nc1-c1ccccc1F)N(CC1CC1)CC1CC1 +O=C1CC(c2ccco2)Cc2nc(Nc3ccc(F)cc3)ncc21 +CCN(CCC#N)C(=O)c1cc(Cl)ccc1OC +Cc1ccnc(NC(=O)c2ccc3c(=O)n(C)c(=O)n(C)c3n2)c1 +Cc1ccc2c(c1)CCCN2C(=O)Cn1cnnn1 +CCN(CC(=O)N(C)C(C)C)Cc1nc2ccccc2c(=O)[nH]1 +COC1CCN(C(=O)c2cc3ccccc3s2)CC1 +COCCOc1ccc(NC(=O)NCc2ccccn2)cc1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)N2CCCC2)c1 +CC1Cc2ccccc2C1NC(=O)CNC(=O)c1ccc(F)cc1F +COCCNC(=O)NCCc1ccc(C)cc1C +CCN(C(=O)CS(=O)(=O)c1ccccc1F)C1CC1 +CC(C)(C)NC(=O)CNC(=O)NC1CCN(CC(F)(F)F)C1 +O=C(C1COc2ccc(Cl)cc2C1)N1CCCC1c1ccncc1 +COc1ccc2c(c1)nc(C(C)=O)n2Cc1ccc(F)cc1 +Cc1cn2c(CN3CCCC(c4nccs4)C3)c(C)nc2s1 +CCNC(=O)c1ccc(NC(=O)CCc2nc(C)no2)c(C)c1 +CCOC(=O)c1c(C)[nH]c(C(=O)OCC(=O)N2CCOCC2)c1C +Cc1ccc(N2CC(C)N(C(=O)Cc3ccc(O)cc3)CC2=O)cc1 +CCC(C)NC(=O)CNc1cccc(C(=O)NC)c1 +COC(=O)C1CC(OC(C)=O)C2OC(C)(C)OC2C1OC(C)=O +Cc1ccc(-c2c(CO)nnn2Cc2ccccc2F)cc1 +COc1ccc2c(c1)C(c1ccc(O)cc1)NCC2 +O=C(Nc1cccc(-n2cnnc2)c1)c1cc(F)ccc1F +C=C(C)Cn1c(=O)n(CCO)c(=O)c2cc(OC)c(OC)cc21 +COC(=O)CC1C(=O)NCCN1C(=O)c1ccccc1 +COc1ccc(OC)c(-c2cc(C(C)=O)c(C)[nH]2)c1 +CCc1ccc(OCC(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1 +CCc1c(C)nc(Nc2ccccc2)n2c(=O)[nH]nc12 +CC(=O)NC1CCc2nc(N)nc(C(F)(F)F)c2C1 +COc1ccc(CN(C)C(=O)c2ccn(C)c(=O)c2)c(OC)c1 +Cc1cc(NC(=O)c2cccc(OCC(F)F)n2)nn1C +Cc1ccc2ncc(C(=O)Nc3ccc(-n4cccn4)cc3)n2c1 +Cc1noc(CNC(=O)N2CCN(c3nc(C)c(C)s3)CC2)n1 +Cc1cccc(OCC(=O)N(CCC#N)Cc2ccccc2)c1C +N#CCc1c[nH]c2ccc(CCS(N)(=O)=O)cc12 +COc1ccc(OC)c(C(=O)N(C)Cc2nnc3ccccn23)c1 +OC(COc1ccc(F)cc1)CN1CCN(c2ccccc2)CC1 +CCN(CC)C(=O)CCC(=O)NC(C)(C)c1ccc2c(c1)OCO2 +Cc1cccc(C(=O)N(CCC#N)CCN2CCOCC2)c1O +COCc1nc(CSc2ccc(C)cc2)sc1C#N +CCSc1nc2nc3c(cn2n1)C(=O)CC(c1ccccc1)C3 +CCC(=O)N1CCc2nc3ccccn3c(=O)c2C1 +Cc1cccc(-c2nc(CC(=O)N3CCCC3C(N)=O)cs2)c1 +CC(C)NC(=O)CNC(=O)Nc1ccc(Br)cc1Cl +CCCCCNC(=O)Nc1ccn(-c2ncccc2Cl)n1 +O=C(CC1CCc2ccccc21)NCc1cnn2cccnc12 +CCCOc1ccc(C(NC(C)=O)NC(C)=O)cc1OC +Cc1cccc2cnn(CCC(=O)N(C)Cc3cccs3)c12 +CCc1ccc(OCC(=O)Nc2nonc2CC)cc1 +O=C(Cc1ccc(F)c(F)c1)NCC(=O)N1CCc2ccccc21 +CCC(C)C(=O)CSc1nncn1-c1ccc(C)cc1C +CCOCC1CCCN(C(=O)c2ccc(F)cc2F)C1 +CC(C)C(=O)Nc1cccc(NC(=O)N(C)Cc2ccncc2)c1 +CCOc1cc(C#N)ccc1OCc1ccc(C#N)cc1 +CC(C)Cc1nc(CN2CCOC(Cn3cncn3)C2)no1 +CC(=O)Nc1ccc(C(=O)COC(=O)c2ccc(C)s2)c(F)c1 +CCCCN(C)S(=O)(=O)c1ccccc1S(N)(=O)=O +COC(C)(C)CNS(=O)(=O)c1cnn(-c2ccc(F)cc2)c1C +COc1ccc(C)cc1C(=O)CNC(=O)CC(C)C +Cc1ccc(N)c(OCc2ccc(C(N)=O)cc2)c1 +CCOc1ccc(OCC(=O)N2c3ccccc3CC2C(N)=O)cc1 +CCc1cccc(C)c1NC(=O)c1ccc(CN2CCOCC2)cc1 +CCN(Cc1cnn(C)c1)C(=O)Nc1nnc(-c2ccccc2)s1 +CCNC(=O)c1cnc(COc2ccccc2OC)nc1N +O=C(CSc1cccc2cccnc12)Nc1cccc(O)c1 +Cc1ccc(N2CCn3c(SCc4ccccn4)nnc32)cc1 +Cn1ccnc1C(NC(=O)c1cc2ccccc2[nH]1)c1ccc(F)cc1 +COC(=O)C1CCN(C(=O)CCc2ccccc2F)CC1 +Cc1cc(C(CO)Nc2ccccc2Cl)c(C)s1 +COC(=O)CCN(C)C(=O)c1c(C)noc1C(C)C +Cc1noc(C)c1C(C)C(=O)Oc1cccc2c1CCCC2=O +COc1cc(Cl)c(C)cc1NC(=O)C(C)n1cccn1 +C=CCNC(=O)c1nccc2c(OC)ccc(N)c12 +O=C(CCC(=O)c1cccs1)Nc1ccc2c(c1)OCC(=O)N2 +CC1(C)COC(=O)C1OC(=O)CCc1cccc(F)c1F +CC(=O)c1ccc(NC(=O)CSc2ccc(N)cc2)cc1 +CCCC(=O)NCC(=O)Nc1ccc(-n2cnnn2)c(C)c1 +CC(=O)c1ccc(NC(=O)N2CCC(Cn3ccnn3)CC2)cc1C +O=c1[nH]nc(SCCS(=O)(=O)c2ccc(F)cc2)n1C1CC1 +Cc1ccc(NC(=O)CSc2n[nH]c(=O)n2C)cc1 +Cc1nc(C(C)(C)NC(=O)c2ccc(OC(F)F)cc2)sc1C +Cc1ccc(C(O)CNCc2ccc3c(c2)OCO3)c(C)c1 +CCOc1cccc(CCc2nc(CCO)cs2)c1 +Nc1nccnc1C(=O)NCC1(c2ccccc2)CCC1 +Cc1cccc(-n2nc(C)cc2NC(=O)CC2C=CCC2)c1 +COCCCN(C)C(=O)c1cc(C2CC2)nc(SC)c1C#N +CC(CC(=O)NC(C)(C)C(N)=O)c1ccc(C(F)(F)F)cc1 +O=C(NCc1ccc2c(c1)OCCCO2)c1c[nH]c2cccc(F)c12 +C#CCNC(=O)N1CCC(C(=O)N2CCCC(C)C2)CC1 +COc1ccccc1CNc1ccc(Br)cn1 +Cc1nn(Cc2nc(-c3ccncc3)no2)c(C)c1Br +O=C1CCCN1c1ccc(CNS(=O)(=O)N2CCCCC2)cc1 +Cc1nc(C)c(CNc2cccc(NC(=O)c3ccoc3)c2)s1 +CC(=O)NC(C(=O)NC(C)c1cc(C)sc1C)C(C)C +Cc1cc(N)cc2c(CC(=O)Nc3ccccc3)noc12 +CCn1cc(C(=O)Nc2ccc(F)cc2F)c(=O)c2cc(F)ccc21 +C=CCNC(=O)Nc1ccn(Cc2ccccc2)n1 +CC(C)CCNc1cnn(-c2ccccc2)c(=O)c1Cl +CC(C)(C(=O)NCc1nnc2n1CCCCC2)c1ccccc1 +NC(=O)c1ccc2nc(-c3ccncc3)sc2c1 +COc1ccc(-c2nc(CNC(=O)c3ccc4nccn4c3)no2)cc1 +Cc1c(-c2c(C#N)c(N)nc3c2CCCC3)cnn1C +O=C(CCn1ncc2ccc(Cl)cc21)NCC1CCCO1 +C=CCn1c(C)nnc1SCC(=O)Nc1cccc(C)c1 +CCn1c(CC(=O)Nc2ccccc2F)nnc1SCC(N)=O +NC(=O)C1Cc2ccccc2CN1CCCc1nc2ccccc2o1 +Cc1ccc(S(=O)(=O)N2CCCCC2)cc1C(=O)NC(C)(C)C#N +CC(C)(C)C(=O)NCC1Cn2c(-c3ccccc3)cnc2CO1 +O=C(c1ccoc1)N1CCCCC1CCN1CCOCC1 +CCOc1ccccc1N1CCN(CC(=O)NCc2ccco2)CC1 +CC1c2cccn2CCN1Cc1cccc2cccnc12 +CCn1nnc2cc(C(=O)Nc3ccc4[nH]nc(C(N)=O)c4c3)ccc21 +COc1cn(-c2ccccc2)nc1C(=O)NC(C)C1CCCO1 +Cc1nc2nc(C)c3c(=O)n(-n4cnnc4)ccc3n2n1 +COCC(C)NC(=O)CNc1cccc(S(C)(=O)=O)c1 +CN(CCOc1ccc(F)cc1)C(=O)c1cn(C)nc1C(F)(F)F +COc1ccc(-c2cn(-c3ccc(N)cc3Cl)nn2)cc1F +Cc1noc(CNc2ccc(C(=O)N3CCc4ccccc43)cc2)n1 +Cc1ccccc1NC(=O)CSc1nc(C2CCCO2)n[nH]1 +CCOc1cccc(C(=O)NC(C)C(O)c2ccc(OC)cc2)c1 +COc1ccc(S(=O)(=O)N2CCCC(C(=O)NC(C)C)C2)cc1 +COC(C)c1cccc(NC(=O)N(C)Cc2noc(C)n2)c1 +CC(=O)Nc1ccc(F)c(C(=O)OCC2CC2(Cl)Cl)c1 +CC(=O)c1csc(NC(=O)COc2cccc(C#N)c2)n1 +CCc1c(C)cc(C(=O)N2CCn3c(C(N)=O)cnc3C2)c(=O)n1C +CCCc1noc(CNc2ccc(Br)cc2F)n1 +COc1ccc(C(=O)N2CCN3C(=O)C(C(C)C)NC(=O)C3C2)cc1 +CNS(=O)(=O)c1cc(C(=O)OCC(C)C)ccc1Cl +COc1ccc(CCN2CCN(C(=O)c3cc(C)nn3C)CC2)cc1 +CN(C)S(=O)(=O)c1cccc(C(=O)OCC#N)c1 +COc1ccc(-c2noc(-c3cccc(Oc4cnccn4)c3)n2)cn1 +O=C(CSc1ccc2nnc(-c3ccccc3)n2n1)N1CCCC1 +Cc1ccc(-c2nc(N)n(S(=O)(=O)c3ccc(C)cc3)n2)cc1 +CC(C)NC(=O)c1cnc(CCCc2ccccc2)nc1N +COc1ncnc2c1CCN(C(=O)c1cnc(C)cn1)C2 +CC(c1ccccn1)N(C)C(=O)Nc1ccc2c(c1)oc(=O)n2C +CN(C)C(=O)C1C(N(C)C)=CC=CC1OC1CC1 +Clc1ccc(-c2nnn(Cc3nc(C4CC4)no3)n2)cc1 +Cc1ccc(-c2csc(NC(=O)c3cccc(C#N)c3)n2)s1 +Cc1ccc(C)c(OCC(=O)NCCCC(N)=O)c1 +CC(=O)c1ccccc1OCC(=O)N(C)C1CCCCC1 +COc1cccc(NCc2ccc(-n3ccnc3)cc2)c1 +O=C(NC(c1ccccc1)c1cccs1)c1ccoc1 +O=C(NCCNc1cccnc1)c1cccc2nccnc12 +Cc1cc(C(=O)Nc2nc3ccc(OC(F)(F)F)cc3s2)on1 +CCC(C)CN(C)C(=O)c1cncc(Br)c1 +Cc1ccc(NC(=O)CCCCCNC(N)=O)c(Cl)c1 +O=S(=O)(NCCc1ccccc1)c1cccc(Cl)c1 +CC(=O)Nc1cc(C(=O)COC(=O)c2sccc2C)ccc1O +CC(C)(C)c1noc(Cn2cnc3cnccc3c2=O)n1 +Cc1ccc(OCCCn2nnc(CO)c2C(F)(F)F)cc1 +CCC(O)Cn1nc(C2CC2)nc1-c1ccc2oc(C)cc2c1 +Cc1ccc(Cn2nccc2NC(=O)Cn2ccc3ccccc32)o1 +COCc1nc(CSc2ccc(C)cc2)sc1C(C)=O +Cc1ccc(-c2ccc(C#N)c(=O)n2CCCO)cc1C +CC(C)c1cccc(-c2ccc(C(=O)NCC3(O)CCOC3)o2)c1 +CC1Oc2ccccc2CN(c2ccc(S(N)(=O)=O)cc2)C1=O +O=C(CO)NCCNc1cccc(Br)c1 +COC(=O)C1(N(C)C(=O)c2cccc(OC)c2F)CCCC1 +Cc1ccc(F)c(S(=O)(=O)N(C)CCC(C)C)c1 +CCc1nnc(NC(=O)c2nn(CC)c3ccc(F)cc3c2=O)s1 +COC(=O)c1cc(S(C)(=O)=O)cc(S(C)(=O)=O)c1 +Cc1cnn(CC2CCCN2c2nccc(C(F)(F)F)n2)c1 +CC(=O)c1cc(CC(=O)Nc2ccnn2C(C)C(C)C)cs1 +Cc1cc(Cl)ccc1NC(=O)N1CCOCC1 +CN(CC1=Cc2ccccc2OC1)Cc1nccs1 +COc1ccsc1C(=O)NCc1nnc(C2CC2)n1C1CC1 +O=c1cc(CN(CCO)c2ccccc2)nc2ccccn12 +CCc1ccccc1NC(=O)COC(=O)c1ccccn1 +CC(=O)N1CCC(C(=O)OCCOc2ccccc2)CC1 +Cc1cccnc1NC(=O)Cn1c(-c2cscn2)nc2ccccc21 +CCC(NC(=O)c1ccc2c(c1)OCC(=O)N2)c1ccc(C)cc1 +Cc1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1S(C)(=O)=O +C#CCN1C(=O)C(C)(C(C)C)Nc2cc(OC)ccc21 +CCc1nc(CCNC(=O)c2scnc2C2CC2)cs1 +Cc1occc1C(=O)Nc1cccc(-c2nnc(-c3ccco3)o2)c1 +CC1(C)Cc2cccc(Oc3ccc(N)nc3)c2O1 +CC(C)(C)CC(=O)N1CCC2(CC1)OCCCO2 +COc1ccccc1-c1nnn(-c2ccccc2Cl)c1N +Cc1cc(=O)n(C)cc1NC(=O)c1cccc(-n2cccn2)n1 +CC(c1cccs1)n1ccnc1-c1cnc(-c2ccco2)nc1 +O=C(NCCCNC(=O)C1CCCO1)c1cccc(F)c1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)N1CCC(F)C1 +CN(Cc1ccsc1)C(=O)Nc1ccc(F)cc1Cl +COCC(C)NC(=O)Cc1cccc(C(F)(F)F)c1 +OC(CN1CCOCC1)c1ccc(-c2ccc3c(c2)OCO3)cc1 +CC(=O)Nc1ccc(C(=O)OCC(=O)NC2CC2)cc1 +O=C(NCCc1ccoc1)C(c1ccccc1)c1ccccc1 +O=C(Cn1cccnc1=O)NCCc1ccc2c(c1)OCO2 +Cc1noc(CNCC(O)c2ccccc2Cl)n1 +COc1ccc(SC(C)C(=O)NCc2ccco2)cc1 +CCOC(=O)Cn1c2ccccc2n2c(=O)cc(-c3ccccn3)nc12 +CC(CNC(=O)Nc1ccc2nn(C(C)C)cc2c1)c1nccs1 +Cc1cc(=O)c(C(=O)NCC2CCCCC2)nn1-c1ccccc1 +CC(=O)c1c(C)[nH]c(-c2csc(NC3CC3)n2)c1C +CCC(Oc1cccc(Cl)c1)C(=O)N1CCOCC1 +Cc1cnn(CC(=O)N2CCCN(c3nc(C)cs3)CC2)c1 +Cc1cc(C)cc(C(=O)NCC(=O)N(C)Cc2ccc(F)cc2)c1 +CC(C)CC(NC(N)=O)C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +CC(=O)Oc1ccc2nc(COc3ccccc3Cl)oc(=O)c2c1 +O=C(Nc1cccc(O)c1)c1ccccc1Br +CN(Cc1ccc(C(C)(C)C)cc1)C(=O)c1ccc(S(C)(=O)=O)o1 +CCC(=O)NC(C)c1cc(OC)c(OC)cc1C +Cc1noc2nc(C3CC3)cc(C(=O)Nc3ccccc3F)c12 +CC(=O)c1ccc(N2CCCC(CO)C2)c(Br)c1 +CCN(C(=O)CCCCNC(N)=O)c1ccc(F)cc1 +CCNC(=O)c1cccc(CNC(=O)CSc2ccncc2)c1 +Cc1noc(C)c1COC(=O)C1CC(=O)Nc2cc(F)ccc21 +COCCOc1ncccc1C(=O)Oc1ccc(C)cc1C +CCc1nnc(NC(=O)N(CC)CCc2ccccc2)s1 +Cn1c2ccccc2n2c(-c3cc(N)ccc3Cl)nnc12 +CCCc1ncc(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)s1 +COc1ccc(C)cc1NC(=O)CS(=O)(=O)c1nccn1C +Cc1csc(C(Cc2cccs2)NC(=O)C2CC2)n1 +CNc1snc(C)c1C(=O)N1CCN(c2cccc(C)c2C)CC1 +CCCC(C)c1nnc(NC(=O)Cc2ccc(F)cc2)s1 +CC(NCCOc1ccc2c(c1)OCO2)c1nccs1 +CCC(Oc1ccccc1)C(=O)Nc1ccc(N2CCOCC2)cn1 +COc1cccc(COC(=O)c2sc3ncn(C)c(=O)c3c2C)c1 +Cc1cccc(OCCn2c(C3CC3)nc3c(N)cccc32)c1 +COc1cccc(NC(=O)C2COc3ccccc3C2)c1 +C=CCOC(=O)OCn1c(=O)sc2ccccc21 +O=C(CCC(=O)N1CCSc2ccccc21)NCC1CCOC1 +CCOc1cc(C=Cc2nc(-c3ccc(C#N)cn3)no2)ccc1OC +CCC(OC)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CCC(C)NC(=O)Nc1ccc(Cl)cc1C(=O)N1CCCC1 +NC(=O)c1ccc(OC(=O)COc2ccccc2)cc1 +O=C(c1coc(COc2ccccc2F)n1)N1CCOCC1 +O=C(c1cc(-n2ccnc2)ccn1)N1CCN(Cc2ccccc2)CC1 +Cc1cc(S(=O)(=O)Nc2ccnn2C)c(Cl)cc1Cl +CN(Cc1nccn1C(F)F)C(=O)NCc1cccc(F)c1 +Cc1n[nH]c(C(=O)N2CCCC2c2ccsc2)c1Br +COc1cc2c(c(OC)c1OC)CC(CCC#N)C(=O)N2 +O=C(OCCc1c[nH]c2ccccc12)c1cn(Cc2ccccn2)nn1 +CC(=O)c1ccc(NC(=O)NCc2cc(C(C)C)no2)cc1C +O=C(CN1CCOCC1C1CC1)NCC1CCCO1 +Cc1cccc(NC(=O)CN(C)C(=O)CCc2cc(F)ccc2F)n1 +CN(Cc1ccccc1)c1ncnc2c1cnn2-c1ccc(F)cc1 +COC(=O)NCc1cccc(CNC(=O)OC)c1 +Cc1nccn1-c1ccc(CNC(=O)C(C)C)cc1 +COc1c(C)cc(C)cc1-c1cc(NC2CC2)ncn1 +Cn1ncc2c(N3CCN(C(=O)Cc4ccsc4)CC3)ncnc21 +N#Cc1nc(C2CCCCC2)[nH]c1-c1cccs1 +O=C(CC1C=CCC1)Nc1ccc(N2CCOCC2)nc1 +CC(NC(=O)CSc1ccccc1F)c1cccs1 +CCc1nc2ccccc2c(C)c1C(=O)OCC(=O)NC1CC1 +O=C(NCc1ccccn1)N(Cc1ccc(F)cc1F)C1CC1 +Cc1ccsc1-c1cnc(CNCCc2ccccn2)s1 +O=C(Nc1nc(S(=O)(=O)Cc2ccccc2)ns1)c1ccco1 +Cn1cc(C(=O)Nc2ccccc2)c2ccccc21 +CCCn1c(N)c(N2CCC(Cc3ccccc3)CC2)c(=O)[nH]c1=O +CCc1cc(C(=O)N2CCC(C)CC2)sc1C +O=C(CCNC(=O)N1CCC(c2ccccc2)C1)N1CCCCC1 +COc1ccc(C(=O)NC(C)c2ccc(-n3cncn3)cc2)c(O)c1 +C=CCNc1oc(-c2cccc(Cl)c2)nc1C#N +N#Cc1ccnc(N2CCN(C(=O)CCc3cccs3)CC2)c1 +O=C(OCCn1c(=O)oc2ccccc21)C1CC2CCC1C2 +C#CCNCCN1CCN(c2cccc(Cl)c2)CC1 +COc1ccc2c(c1)N(C(=O)c1nc(C(C)C)cs1)CCO2 +Cc1noc(C)c1CCCNC(=O)NCCc1cc(F)ccc1F +Cc1ccc(-c2cc(C(=O)N3CCCC(c4ccn[nH]4)C3)[nH]n2)s1 +CSc1ccc(CN(CCO)C(=O)C2CC2c2ccccc2)cc1 +COCC(=O)N1CCCN(C(=O)c2ccc(F)c(OC)c2F)CC1 +C#Cc1cccc(N(C)CC(O)Cn2c(-c3ccccc3)noc2=O)c1 +O=S(=O)(Cc1ccccc1)Nc1ccc2c(c1)OCCO2 +Cc1ccc2c(c1)C1(CCN(S(C)(=O)=O)CC1)CN2 +COc1ccc(C=c2sc3nc(-c4cccnc4)nn3c2=O)cc1 +Cc1nc(-c2ccc(CNC(=O)c3cccc(F)c3)cc2)cs1 +O=C(COc1ccc(F)cc1F)NCCCn1nnc2ccccc21 +CNS(=O)(=O)c1cc(NC(=O)c2ccncc2)ccc1C +O=C(Nc1ccc2nc3n(c(=O)c2c1)CCCC3)c1cccc(F)c1 +Cn1ncc2c(N3CCOCC3)nc(C(C)(C)C)nc21 +Cc1csc(CNC(=O)C2CC(=O)N(C3CCCC3)C2)n1 +CCc1cccc(CC(=O)NCc2nc(C)sc2C)c1 +CC(C)Oc1ccccc1C1CC(O)=Nc2c1ncn2-c1cccnc1 +COc1ccc(COC(=O)c2ccn(-c3ccccc3)n2)cn1 +Cc1nnc(Oc2cccc(-c3nnco3)c2)c(C#N)c1C +CC(C)=CC1C(C(=O)N2CCN(C)CC2)C1(C)C +Cc1cc(=O)n(CC(=O)Nc2c(C)cccc2C)nc1C +FC(F)(F)c1nnc(NCc2cnn(-c3ccccc3)n2)s1 +C#CCN1CCN(C(=O)NC(C)CC(C)(C)OC)CC1 +CN1C(=O)Cc2cc(NS(=O)(=O)C3CC3)ccc21 +C=C(C)CN(CC)C(=O)c1cc(COc2ccc(C)nc2)on1 +CCCCn1nccc1NC(=O)CCC1CCCC1 +CCOC(=O)CN(C)C(=O)c1cccc(Cl)c1Cl +CN(CCCNC(=O)C1CC=CCC1)S(C)(=O)=O +COc1ccc(OC)c(CN(C)C(=O)Nc2ccc(C#N)cc2)c1 +CC(C)(C)C(=O)N1CCN(C(=O)C2COc3ccccc3O2)CC1 +COc1ccccc1CN(c1ccc2nnnn2n1)C1CC1 +COCCNC(=O)CN(C)Cc1nc2c(cnn2C)c(=O)[nH]1 +CC(C)N(CCC#N)S(=O)(=O)c1ccccc1N +CCOC(=O)C(CC)C(O)c1ccc(OC)c(Br)c1 +Cc1cc(CN2CCN(C(=O)C3Cc4ccccc4S3)CC2)no1 +CC(C)C(NC(=O)COc1ccccc1)C(=O)N1CCOC(C)(C)C1 +CC(C)(C)OC(=O)Nc1ccc2c(c1)NC(=O)CN2 +Cn1c(CCNCc2cccc3c2OCO3)nc2cc(F)ccc21 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1cccc(F)c1 +CCN(CC)C(=O)c1ccc(NCc2nc(C)no2)cc1Cl +CCCCC(=O)Nc1ccc2c(c1)N(C(C)=O)CC2 +Cc1nn2c(C#N)c(-c3ccc(NC(=O)C4CC4)cc3)nc2s1 +CCc1cccc(C)c1NC(=O)CN1CCCCC1=O +Nc1oc2c(c1-c1nc3c(s1)CCCC3)C(=O)CCC2 +Cc1cc(N2CCCC2)nc(CNC(=O)c2ccccc2)n1 +COc1ccc2ncnc(Sc3nccn3C)c2c1 +CC(NC(=O)NCC(=O)N1CCCC1)c1cccc(OC(F)F)c1 +COCc1ccc(C(=O)Nc2cc(C(=O)OC)ccc2C)cc1 +Cc1ccccc1-n1cc(C(=O)Nc2ccnn2C(C)C)cn1 +O=C(c1ccsc1)N1CCc2onc(CN3CCOCC3)c2C1 +Cc1cc(NC(=O)C(C)N2CCOC(c3nc(C)cs3)C2)on1 +O=C(CC1CCOCC1)N1CCC(OCc2ccc(F)cc2)CC1 +Cc1ccc(Cn2nccc2NC(=O)C2CC2c2ccccc2C)o1 +Cc1cnc2c(S(=O)(=O)NCCc3cccc(F)c3)cccc2c1 +O=C(CCc1ccccc1F)Nc1ccc2c(c1)OCCO2 +COC(=O)Nc1cccc(NCC(=O)Nc2ccccc2Cl)c1 +Cc1cccc(C(CC(=O)Nc2nc(C(C)C)cs2)NC(N)=O)c1 +O=C(Nc1cccnc1)C1CCN(C(=O)C2CC2)CC1 +Cc1ncc(CN(C)C(=O)NCC2(c3ccccc3)CC2)s1 +CC1CCC(CO)(NC(=O)C(C)NC(N)=O)CC1 +COc1ccc(CC(=O)OCC(=O)Nc2cccc(F)c2)cc1 +O=C(Nc1ccc2c(c1)COC2)NC1CCCC2OCCC12 +O=C(NCc1ccccc1-n1ccnc1)C1CC2CCC1C2 +COC(=O)c1sccc1CSc1nnc(C2CC2)s1 +CCOc1ccccc1C(=O)N1CCCN(C(=O)OC(C)(C)C)CC1 +CC(=O)N1CCN(c2csc3ccc(C)cc3c2=O)CC1 +CCN(C(=O)CNc1ccccc1N(C)C(C)=O)C1CC1 +O=C(NC1CCCCC1)c1cccn1-c1nnc(N2CCCC2)s1 +Cn1cnc(S(=O)(=O)NCCc2ccccc2)c1 +COCCCNc1nc(Nc2ccccc2)c2cnn(C)c2n1 +COc1ccc(C)cc1C(C)NC(=O)CCc1c(C)noc1C +CCC(=O)Nc1cc(-c2cccs2)nn1-c1nc(CC)cc(=O)[nH]1 +O=C(NC1CCN(C(=O)NC2CCCCC2)CC1)c1ccco1 +CCOC(=O)Cc1c(C)nc2c(C#N)cnn2c1C +CCCNC(=O)CN(C1CCCCC1)S(C)(=O)=O +CC1CCN(C(=O)c2ccc3c(c2)N(S(C)(=O)=O)CC3)CC1 +CCOc1ccc(F)cc1NC(=O)c1cc(C)n(C(C)(C)C)n1 +CSc1ccc(OC(=O)C2CCOc3ccccc32)cc1 +O=C(Cn1nnnc1C1CCCC1)N(Cc1ccccc1)C1CC1 +COc1ccnc(Nc2ccc(N3CCOCC3)nc2)n1 +Cc1nnsc1C(=O)N1CCN(S(=O)(=O)C2CC2)CC1 +CCc1ccc(NCc2noc(-c3ccoc3)n2)cc1 +CC(C)(CNC(=O)c1sccc1OC(F)F)c1ccncc1 +CC(=O)Nc1ccc(-c2cc(C(F)(F)F)cnc2N(C)C)cc1 +COc1ccc(OC(C)C(=O)N2CCN(Cc3ccco3)CC2)cc1 +C=CCN(CC1CCCCC1)C(=O)c1cc(C(N)=O)cs1 +CCNS(=O)(=O)c1ccc(F)c(C(=O)N2CCCC(OC)C2)c1 +CC(C)c1nnc2n1CCN(C(=O)c1csc(C3CC3)n1)C2 +CN(CC(=O)N1CCCC(C(N)=O)C1)S(C)(=O)=O +Cn1cnnc1C1CCCN(C(=O)NCc2ccc3c(c2)OCO3)C1 +N#Cc1ccc(OC2CCC(NS(=O)(=O)c3c[nH]cn3)CC2)nc1 +Cn1nnnc1NCc1ccccc1OCc1ccccc1Cl +CC(CNC(=O)NCC(C)(C)c1ccncc1)Oc1ccc(F)cc1 +O=C1CCc2cc(NC(=O)c3ccc(-n4cccn4)cc3)ccc2N1 +O=C1CCCCN1c1ccc(Br)cc1F +CCc1onc(C)c1NC(=O)CC(C)Cc1cccc(F)c1 +CCOC(=O)C1CCN(C(=O)c2csc(-n3cccc3)n2)CC1 +COC(=O)c1ccc(Cl)c(-c2cc(=O)cc[nH]2)c1 +CC(C)(C)OC(=O)N1CCN(C(=O)COc2ccccc2C#N)CC1 +Cc1ccc(S(=O)(=O)Nc2ccc(-n3cnnn3)cc2)c(C)c1 +Cc1cc(Cn2cnc3sc(C)cc3c2=O)no1 +N#CC(NC(=O)CCOc1ccccc1)c1ccccc1Cl +Cc1ccc(SCCC(=O)Nc2onc3c2CCC3)cc1 +O=C(Nc1ccncc1)c1cccc(Oc2cnccn2)c1 +CC(=O)Nc1cccc(NC(=O)CCc2ccccc2F)c1 +Cc1cc(NC(=O)COc2ccc(F)cc2F)no1 +CC(NC(=O)C1CCOCC1)c1ccc(Cl)c(Cl)c1 +CCOc1ccc2nc(C(=O)NC3CCCCC3)cn2n1 +CC(C)(C)OC(=O)Nc1cccc(CN2CCN3C(=O)NCC3C2)c1 +CC(c1cccnc1)N(C)C(=O)Cn1cc(C(F)(F)F)ccc1=O +COc1c(C)cnc(CNC(=O)NC(C)c2ccc(F)c(F)c2)c1C +CCOc1nccnc1N1CCC(NC(=O)c2cnccn2)C1 +CCOCc1ccccc1CNC(=O)N1CCOC(C)(C)C1 +c1ccc(CSc2cc(N3CCCC3)ncn2)cc1 +N#Cc1ccc(OC(=O)CC(c2ccccc2)C(F)(F)F)cc1 +CCNC(=O)CN(CC)C(=O)c1nc2nccc(C)n2n1 +COc1ccccc1-c1c(CO)nnn1Cc1cccc(F)c1 +CCOc1ccc(C(C#N)CCC(=O)N2CCCC2)cc1 +COc1ccc(Br)cc1CNC(=O)c1cccnc1 +COc1ccc(-c2cn3cc(N)cc(OC)c3n2)c(C)c1 +O=C(NCc1ccc(Cl)cc1Cl)c1ccc2ccnn2c1 +COc1cc(F)ccc1-c1ccc(=O)n(CC(=O)C(C)(C)C)n1 +COC(=O)c1nn(C(=O)OC(C)(C)C)c2cccc(N)c12 +Cc1ccccc1OCCNC(=O)c1c(C)nn(C)c1C +CN(C(=O)CSc1nc2ccccc2o1)c1ccccc1 +CCC(=O)Nc1nc2ccc(C(=O)OC)cc2s1 +COc1cc(C(=O)Nc2ccccc2C(C)=O)cc(OC)c1OC +CCc1ccc(OCC(CC#N)N2CCOCC2)cc1 +COC(=O)c1cn2cc(Br)cnc2n1 +CNC(=O)C(C)S(=O)(=O)c1ccc2ccccc2c1 +O=C(Cc1nnc(-c2cnccn2)o1)Nc1ccc(F)c(F)c1 +Cc1cc(NC(=O)C2CC2c2ccc(F)cc2)n(C(C)(C)C)n1 +O=C(CCn1nc(-c2cccs2)oc1=O)Nc1ccc(F)cc1 +O=C(NCCOCC(F)(F)F)Nc1ccc(-c2nccs2)cc1 +CC(=O)N1c2ccccc2CC1C(=O)NCc1ccc2c(c1)OCO2 +COc1ccc2[nH]cc(CCNC(=O)c3csnn3)c2c1 +COc1ccc(CNC(=O)C(C)Oc2ccc(F)cc2)cc1OC +O=C(c1ccsc1)N1CCN(c2ccccc2F)CC1 +O=C(CSc1nc(-c2cccnc2)n[nH]1)Nc1ccccc1Cl +Cc1cc(OCC(=O)N(C)CCC#N)ccc1Cl +O=C(NC1CC1)c1cnc(Cc2ccccc2)s1 +Cc1ccc2c(c1)NC(C)C(=O)N2CC(=O)OCC(C)C +CCCS(=O)(=O)c1ccc2c(c1)NC(=O)C(C(C)C)O2 +c1cnc(-c2cnc(NCC3CCCO3)nc2C2CC2)cn1 +Cc1n[nH]c(C)c1NC(=O)CNC(=O)c1cccc(F)c1 +Cc1ccc(NC(=O)c2ccco2)c2cccnc12 +COc1ccc(Cl)c(NC(=O)Cn2ncc(=O)c3ccccc32)c1 +Cc1ccc(-c2nc(C(=O)NCc3ccccc3Cl)no2)cc1 +Cc1cc(NC(=O)c2cc3c(C)nn(C)c3s2)n(C)n1 +Cc1ccncc1NC(=O)NC(C)Cc1ccccc1F +CC(C)c1nc(CC(=O)Oc2ccc3c(c2)OCO3)cs1 +COCCNC1=NS(=O)(=O)c2cc(F)ccc2N1 +COCc1ncc(C(=O)Nc2cccnc2)c(N)n1 +CC1CCN(C23Oc4ccc(O)cc4C2CCCNC3=O)CC1 +CC1CCC(N(C)C(=O)C2CCN(C(=O)c3ccoc3)CC2)CC1 +O=C(Cn1ccnc1)NC1CC2(CCOCC2)Oc2ccccc21 +CC1CCc2nc(NC(=O)CCn3cc(Cl)cn3)sc2C1 +Cn1nccc1-c1nn2c(-c3ccccn3)nnc2s1 +CCC(=O)N1CCCN(C(=O)c2ccc(=O)n(C)c2)CC1 +O=C(Nc1nccs1)N1CCC(c2nc3ccccc3[nH]2)CC1 +CC(C)n1cnnc1CCNC(=O)C1(c2ccc(Cl)cc2)CC1 +O=C(CCNC(=O)NCc1ccccc1)Nc1ccccc1 +CCCN(C)C(=O)CCCS(=O)c1ccc(Br)cc1 +CCn1ccc(=O)nc1SCCN(C)c1ccccc1 +CC(C)C(NC(=O)N(C)Cc1cnn(C)c1)c1ccccc1 +CSc1cc(C(=O)NC2CCCc3occc32)ccn1 +CN(Cc1cccc(C#N)c1)C(=O)c1cncc(Br)c1 +COC(=O)C1CCN(C(=O)C2(c3ccc(F)cc3)CC2)CC1 +COC(=O)c1cc(Cl)c(C(=O)OC)cc1Cl +CNc1snnc1CN(CCC#N)CC(C)C +Cc1ccc(NC(=O)c2cnc(-c3cccs3)nc2N)cc1 +CCOc1cccc(C(=O)N(C)C2(C#N)CCC2)c1 +O=C(CCn1ccccc1=O)Nc1nncs1 +CC(C)(C)OC(=O)N1CCC(CNc2ncc(Cl)cn2)C1 +COCCNC(=O)C(O)C(C)c1ccc(C)cc1 +O=C(Cn1ccccc1=O)Nc1ccc(F)cc1OCC(F)(F)F +CN(CCOc1ccc(F)cc1)S(=O)(=O)C1CCOC1 +c1nc(N2CCC(c3cn[nH]c3)CC2)c2ccsc2n1 +Cc1cc(OCCN2CCCS2(=O)=O)ccc1Cl +CC1CCCC(OCC(=O)N2CC(C)C(N3CCOCC3)C2)C1 +c1cc(COCC2CC3OCCN(Cc4ccsc4)C3C2)ccn1 +Cc1cccc(N2CCN(C(=O)c3cn4ccccc4n3)CC2)c1C +COCCNC(=O)CNC(=O)c1ccc2c(c1)NC(=O)CS2 +CCc1nnc(SCC(C)C)n1-c1ccccc1 +COc1ccc(Br)c(S(N)(=O)=O)c1 +CC(=O)c1c(C)cc(C)c(Cn2nc(C)c(C)c(C#N)c2=O)c1C +CC(=O)Nc1ccc(CCNC(=O)c2cccc3ccc(C)nc23)cc1 +CC(OC(=O)C1COc2ccccc2O1)C(=O)c1ccccc1 +CNC(=O)c1cc2c(n1C)CN(c1nc(C)nc3oc(C)nc13)CC2 +Cc1cc(C2CCCN2Cc2noc(C(C)(C)C)n2)no1 +CCCn1nc(C(=O)N2CCCCCC2C(C)(C)C)ccc1=O +CC(C)c1csc(N2C3CCCC2CC(=O)C3)n1 +CC(C)N(C)C(=O)NCCN(C)C(=O)OC(C)(C)C +COc1cc(F)ccc1-c1nc2c([nH]1)c(-c1cccnc1)nn2C +CCc1noc(C(C)Sc2nnc(-c3cccnc3)n2C)n1 +CC(=O)c1ccccc1NCC(=O)NCCc1ccc(F)cc1 +C#Cc1cccc(NC(=O)c2cc3ccccc3[nH]c2=O)c1 +C#CCOc1ccccc1C1Nc2ccccc2C(=O)N1CC=C +CCCC(=O)N1CCCCC1C(=O)Nc1ccc(-n2cncn2)cc1 +Cc1ccc(NC(=O)N(C)C(C)c2ccco2)cc1F +CC(C)n1nccc1NC(=O)Cc1ccc(Br)cc1 +CCCCOc1ccc(CNC(=O)N2CCOCC2C)cc1OC +COC(=O)C1CN(c2ccccc2F)CCC1=O +CCn1cnnc1CNC(=O)NC(C)Cc1ccsc1 +CC(Cc1ccccc1F)NC(=O)N1CCOC(C)(C)C1 +Cc1ccc(C(=O)NC(C)C(=O)NC2CCCC2)n1C +CC(=O)N1CCc2[nH]cnc2C12CCN(C(=O)c1ccncc1)CC2 +COc1cccc2sc(NC(=O)CC3C=CCC3)nc12 +Cc1cc(C)c(NC(=O)c2cc(C)sc2C)c(C)n1 +COc1ccccc1C(CNS(=O)(=O)c1cccs1)OC +Cc1nc(-c2cccc(NC(=O)c3ccnn3C)c2)no1 +O=C(N1CCCCCC1)C1(S(=O)(=O)c2ccc(Cl)cc2)CC1 +CC(C)(C)C1CCc2c(sc(NC(=O)C3CC3)c2C(N)=O)C1 +Cc1cccc(OCc2nc3ccc(N)cc3o2)c1C +CC(=O)c1csc(COc2ccc(C)cc2C)n1 +COc1ccc(NC(=O)Nc2ccccc2)c(N)c1 +COCCN1C=NC2(CCC(C(=O)Nc3ccc(C)cc3)CC2)C1=O +CCN(CCC(=O)OC)C(=O)c1ccc(OC)c(F)c1 +O=C(Cn1ccc(=O)[nH]c1=O)NCCc1ccc2c(c1)OCO2 +Cc1ccc2ncc(C(=O)N3CCC(N4CCCCC4=O)CC3)n2c1 +Nc1cc(F)ccc1NC(=O)C1COc2ccccc2O1 +Cn1cnnc1-c1cccc(NC(=O)Cc2cccc(F)c2F)c1 +Cc1cc(C(C)NC(=O)c2cn3cccnc3n2)c(C)s1 +NC(=O)C(Sc1nc2cc(Cl)ccc2[nH]1)c1ccc(F)cc1 +c1ccc2c(c1)CCN2c1c2c(nc3ncnn13)CCC2 +O=C(NCc1ccccc1)N1CCN(Cc2cccs2)CC1 +CCOC(=O)c1cc2cc(NC(N)=O)ccc2s1 +CCN(CC(=O)OC)S(=O)(=O)c1ccc(O)cc1 +Cc1ccc(NC(=O)Cn2nnc(-c3ccc(Cl)cc3)n2)c(F)c1 +C=CCn1ccc2c(OCC(N)=O)cccc2c1=O +Cc1sc(=O)n(CC(=O)OCCCC(C)C)c1C +O=C(CC1CCCCC1)N1CCCN(C(=O)c2ccccc2F)CC1 +O=C(NCCO)c1ccccc1Nc1ccccc1 +O=C(Cn1c(=O)oc2ccc(Cl)cc21)NCCc1ccc(F)cc1 +O=C(NCCNC(=O)c1ccccc1O)NC1CCCc2occc21 +COCC(NC(=O)c1cccc(F)c1F)C(N)=O +Cc1noc(C)c1C(=O)N1CCCN(Cc2nccn2C(C)C)CC1 +O=C(NCc1cccs1)Nc1nc2c(F)cccc2s1 +N#CCCN(CCC(F)(F)F)C(=O)c1cccc2c1OCC(=O)N2 +CCOc1ccc(OCC)c(NCC(=O)N2CC(C)OC(C)C2)c1 +CSc1ccc(OC(C)C(=O)NCC(O)c2ccccc2C)cc1 +COc1ccc(C(=O)CN2CCN(CCO)CC2)c(OC)c1 +COC(=O)c1ccc(C)c(C(O)c2ccccc2)c1 +CN(CC(=O)N1CCCC1)C(=O)c1cc(-c2cccc(Cl)c2)on1 +Cc1cc(=O)[nH]c(CNC(=O)c2csc(C)n2)n1 +CCn1nc(-c2ccc(F)cc2F)cc(C(C)=O)c1=O +O=C(NC1CC1)c1cccc(NC(=O)c2coc(-c3ccccc3)n2)c1 +CCN(C(=O)Cn1cc(C(F)(F)F)ccc1=O)c1ccccc1 +COc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)c(OC)c1 +COc1ccc(OC)c(C(O)CNC(=O)NC2CCCCCC2)c1 +CC1CCCN(C(=O)Cc2nc3ccc(N)cc3o2)C1 +Nc1ccccc1S(=O)(=O)Nc1cccc(Br)c1 +COCc1ccc(CNC(=O)NC(C)(CO)C2CCCCC2)cc1 +CC(=O)N1CCN(c2ccccc2NC(=O)c2cccc(F)c2)CC1 +CSc1ccc(NC(=O)Cn2cnc(N)n2)cc1 +O=C(COc1ccccc1)N1CC=C(c2c[nH]c3ncccc23)CC1 +Nc1ccc2c(NCCCO)ncc(Br)c2c1 +CCCc1nnc(N2CCC(NC(=O)Nc3ccccc3)CC2)s1 +Nc1cc(N2CCCC(COc3ccc(F)cc3)C2)nc(N)n1 +CC(C)(C)C(=O)Nc1nc2cc3c(cc2s1)OCCO3 +CCc1cc2c(SCCCCC#N)ncnc2s1 +O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)N1CCCC1 +O=C(Nc1cccnc1-n1cccn1)c1ccccn1 +COc1ccccc1C(NC(=O)Nc1ccccc1)c1noc(C)n1 +O=C(Nc1cc[nH]n1)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +CCN(C(=O)CCc1c(C)nc(C)[nH]c1=O)c1ccc(F)c(F)c1 +Cc1nc(-c2ccsc2)sc1C(=O)N(CC(N)=O)C(C)C +COC(=O)C1CCN(C(=O)c2ccc[nH]c2=O)CC1 +CCN(CCC(=O)OC)C(=O)c1c(C)c(C)nn(C)c1=O +Cc1ccc(N2CCC3OC(C(=O)NCC4CC4)CC32)nn1 +CCCn1nc(C(=O)NC(C)C2CCCO2)c2ccccc2c1=O +COc1ccc(CNCC(C)c2nc(-c3ccccc3)no2)cc1C#N +Oc1cc(O)c2c(c1)C(c1ccc(Cl)cc1F)NCC2 +O=C(CCCn1cncn1)NC1CCCCC1Oc1ccccc1 +O=C(NCCc1c[nH]c2cc(F)ccc12)C1CCOC1 +CC1(C)CN(Cc2nc(N)c3ccccc3n2)CCO1 +CC(C)OC(=O)CSc1nc2c(cc1C#N)CCC2 +CC(C)CNC(=O)Cn1c(C(C)C)ccc(C#N)c1=O +O=C(Cn1nnc(CO)c1C1CC1)Nc1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)c2cnc(C3CC3)nc2N)cc1 +O=C(CNC(=O)c1ccc2cc[nH]c2n1)Nc1cccnc1 +COc1ccc(-c2cc(C#N)nc(N(C)C)n2)cc1C +CCCCN(C(=O)c1ccc(NC)cc1)C(C)CC +CCc1ccc(OC)c(-c2c(CCOC)noc2N)c1 +CCC(=O)N1CCCN(Cc2nc3ccccc3c(=O)[nH]2)CC1 +Cc1cccc(OCC(=O)Nc2c(C)cccc2C)c1 +CCN1CC(C(=O)Nc2ccc(Br)c(C)c2)CC1=O +Cc1cn(-c2ccccc2)nc1NC(=O)C(C)c1ccsc1 +Cc1cnc2c(c1)nc(-c1ccccc1C)n2CC#N +CCN(CC)C(NC(=O)c1ccccc1)C(=O)c1ccccc1 +NC(c1ccc(O)c(Br)c1)C(F)(F)F +O=C(NCC1CCCOC1)c1cc(-c2cccs2)on1 +COCC(C)NC(=O)c1ccccc1SCc1ccc(C#N)cc1 +CC(C)C(=O)NCC1CCCN(C(=O)Nc2cccc(F)c2)C1 +COC(=O)C(C)n1c(=O)c(C)c(O)c2ccc(N)cc21 +COc1ccccc1CNC(=O)c1cccc(-c2ccoc2)c1 +O=C(Nc1nccs1)NC1CC1c1cccc(Cl)c1 +Cc1ccc(NC(=O)Cc2cccs2)c2[nH]ncc12 +CCc1cc(O)n2nc(C3CCCCN3C(=O)C3CC3)cc2n1 +O=C1CC(CNc2ncnc3[nH]cnc23)CN1CCc1ccccc1 +CCCc1nnc(SCC(=O)Nc2ccc(OC)cc2)n1N +CN1CCN(S(=O)(=O)c2ccc(-c3csnn3)s2)CC1 +Cc1cccc(NC(=O)Cn2c(=O)n(C)c(=O)c3nscc32)c1 +COc1nccnc1N1CCC(NC(=O)COc2ccccc2C)C1 +Cc1ccc(NC(=O)COc2ccc(-c3nnco3)cc2)cc1 +Cc1cc(CNS(=O)(=O)c2ccc(F)cc2)c(C)o1 +Cc1c(-c2ccnc(N3CCOCC3)n2)cnc2nc3ccccc3n12 +O=C(CN1CCCS1(=O)=O)Nc1ccc(Oc2ccccc2)cc1 +COc1ccc(NC(=O)CCCc2nc(C)no2)cn1 +Nc1c(Cl)ccnc1N1CCN(c2ccccc2)CC1 +COCCN1CCN(C(=O)CN2CCCC2=O)CC1 +CCCCOC(=O)CN1CCN(c2cccc(F)c2C#N)CC1 +CC(C)(C)Oc1cc(CNC(=O)c2ccc(C(N)=O)cc2)ccn1 +COC(=O)c1ccc(Cl)c(NCCCN2CCOCC2)c1 +O=C(c1cccc(-c2ccoc2)c1)N1CCN(c2cccc(O)c2)CC1 +Cc1cccc(S(=O)(=O)NCCC(O)c2ccccc2)c1 +O=C(Nc1cccnc1N1CCCC1)c1ccc2ccccc2n1 +CCOC(=O)c1nn(-c2ccc(F)cc2F)c(N)c1C#N +COc1ccc(OC)c(Nc2c3c(nc4ncnn24)CCC3)c1 +COc1cccc(C=Cc2ccn(CCO)c(=O)c2)c1 +Nc1cccc2c1OCCN2C(=O)Nc1ccccc1 +N#CCc1ccc(NC(=O)NCCCCn2ccccc2=O)cc1 +CC(=O)NCC(=O)Nc1cccc(OCCn2cccn2)c1 +CCn1ccc(C(=O)N2CCCN(C(=O)OC(C)(C)C)CC2)n1 +COC(=O)Nc1ccc(CNS(=O)(=O)c2ccc(C)s2)cc1 +CCC(C)N(CC)S(=O)(=O)c1ccc(N)cc1Cl +CCCNC(=O)c1ccc(NCC(=O)NCC)cc1 +CNC(=O)N(C)CCc1noc(C(=O)NCc2ccccc2)n1 +CCc1ccccc1NC(=O)c1cc2ccc(O)cc2oc1=O +Cc1c(C(=O)NC(C)C)oc2c1C(O)CC(C)(C)C2 +COc1ccc(CNc2ncnc3c2cnn3C)cn1 +COc1ccc(F)cc1-c1cn2cc(N)ccc2n1 +O=C(CSc1nc(CC2CCCC2)n[nH]1)NC1CC1 +CC(=O)N(Cc1ccc(NC(=O)c2ccncc2F)cc1)C1CC1 +COC(=O)C(NC(=O)Cc1ccncc1)c1cccc(C)c1 +O=C(NCCc1c[nH]c2cc(F)ccc12)Nc1ccncc1 +CC(C)NC(=O)NC(C)COc1ccccc1F +Cc1ccc(NC(=O)NC2CCN(C(=O)N3CCOCC3)CC2)cc1 +Cc1nc(C2CCCN(Cc3ccsc3)C2)cc(=O)[nH]1 +COc1ccnc(NC(=O)c2cc(OC)ccc2O)c1 +COC(=O)c1ccccc1Cn1ccnc1CC(F)(F)F +COCCn1c2c(ccc1=O)CCN(C(=O)c1cc(C)oc1C)CC2 +Cc1ccc(C(=O)N2CC3CCC(C2)N(CC2CCC2)C3=O)c(=O)[nH]1 +N#Cc1cc(F)ccc1NC(=O)N1CCN(c2ccccc2)CC1 +COc1ccc(N(C)C(=O)c2c(F)cccc2Cl)cn1 +CC(C)Cc1nnc(NC(=O)c2ccncc2)s1 +Cc1[nH]c2cc(C3CCCC3)nn2c(=O)c1CCO +O=C(NCCOc1ccc(F)c(F)c1)C1CC=CC1 +CCOc1cccc2sc(NC(=O)c3cc(C)nn3C(C)C)nc12 +Cc1ccc(CNC(=O)CCn2c(=O)n(C)c3ccccc32)cc1 +O=C(Nc1ccccc1C(=O)N1CCCC1)C1CCC1 +C=CCN(CCc1ccccc1)C(=O)C1CCCN1C(=O)C(C)C +CC(NS(=O)(=O)c1cccc(C(=O)N(C)C)c1)c1ccncc1 +Cc1cc(C(=O)OCc2nnc(-c3ccccc3Cl)o2)c(C)s1 +CC(=O)N1CCc2ccc(NC(=O)c3ccc(F)cc3Cl)cc2C1 +CC(c1nccs1)N(C)C(=O)c1cnc(-c2cccnc2)nc1 +COc1ccccc1CC(=O)N1CCCC(n2nc(C)nc2C)C1 +COC1CCCCC1OC(=O)c1ccc2nnn(C)c2c1 +COC(CNC(=O)Nc1cc(C)on1)c1ccccc1 +CCN(CC)S(=O)(=O)c1sccc1Br +Cc1ccc(N)c2ccnc(C(=O)N3CCOCC3)c12 +N#Cc1cc(Cl)ccc1NCc1ccc(O)cc1 +Cc1nccnc1S(=O)CC1CCCN(C(=O)OC(C)(C)C)C1 +CC(C)(C)c1cc(C(=O)C(C#N)c2ccc(C(F)(F)F)cn2)[nH]n1 +CC(=O)NCC(=O)N1CCN(c2cccc(C)c2)CC1 +CCCCCC(=O)Nc1cccc(C(=O)N2CCCCC2)c1 +Cc1ccccc1-c1noc(C2CCN(C(=O)c3ccccn3)CC2)n1 +COCCn1cc(NC(=O)NC2CCc3ccccc32)cn1 +COc1ccc2[nH]cc(C(=O)NCc3cccnc3)c(=O)c2c1 +O=C(Nc1ccccc1)C1CCCN1C(=O)c1cc(C2CC2)on1 +CCc1onc(C)c1NC(=O)N(C)CCOc1ccc(F)cc1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2cccc(NC(C)=O)c2)c1C +Cc1csc2nc(Cc3ccc(C(F)(F)F)cn3)[nH]c(=O)c12 +CC(CC(=O)c1cccs1)NC(=O)c1cccc2cc[nH]c12 +COc1cccc(S(=O)(=O)C(C)C(=O)NCC(C)C)c1 +CCc1sc(C(=O)Nc2ccc3c(c2)OCCO3)cc1C +Cc1sc2nc(COC(=O)c3ccc(O)cc3)[nH]c(=O)c2c1C +Nc1ccc2nc(CCC(=O)N3CCCCC3)cn2c1 +CCc1noc2nc(C)nc(Nc3ccc(OC)cc3OC)c12 +N#CCc1ccc(OS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)cc1 +Cc1ncc(C(=O)N(C)C(CO)C(C)(C)C)c(C)n1 +O=C(Nc1ccc(C(=O)N2CCOCC2)cc1)C1CCC1 +Cc1ccc(-c2nc(C)sc2CC(=O)OCC2(C)COC2)cc1 +COC(=O)Nc1cccc(C(=O)N2CCCC2c2ccc[nH]2)c1 +CCCCNC(=O)Nc1ccc(-n2cncn2)c(F)c1 +CN(Cc1ccc(F)cc1)C(=O)COc1ccc(F)cc1 +CCn1cc(S(=O)(=O)NC2C3CC4CC(C3)CC2C4)cn1 +CSc1ccccc1C(=O)N1CCC(C#N)CC1 +O=C(CO)N1CCN(C(=O)Cc2ccccc2F)CC1 +Cc1nnc2n1CCN(C(=O)CCc1nc3ccccc3s1)C2 +CC(=O)Nc1cccc(C2NCCc3ccc(F)c(C)c32)c1 +CCn1nc(C)c(C(=O)NCc2ccccc2-n2cncn2)c1C +COc1ccc(NC(=O)CCC(=O)c2ccc(F)cc2)cn1 +Cc1csc(CNCC(O)c2c(F)cccc2F)n1 +C#CCCN1CCN(S(=O)(=O)c2ccccc2)CC1 +COc1ccc(-c2cc(=O)oc3cc(OCC(N)=O)ccc23)cc1 +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)NCc1cc(C(C)C)no1 +CC(=O)NCCNC(=O)Nc1ccc(C)cc1OCC(F)(F)F +CC(Cc1ccccc1F)C(=O)Nc1ccn(C)n1 +NC(=O)N1CCCC(C(=O)NC2(c3ccccc3)CCCC2)C1 +O=C(NCC(F)(F)F)c1ccc(C(F)(F)F)cc1 +Cn1cc(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)cn1 +CN(Cc1ccccn1)C(=O)c1n[nH]c2c1CN(S(C)(=O)=O)CC2 +CC(C(=O)Nc1ccc2c(c1)OCO2)N1CCN(CC(F)F)CC1 +O=C(c1ccc(F)cc1F)N(Cc1ccco1)Cc1cccs1 +Cc1ccc(NS(=O)(=O)c2cc(-c3ccno3)oc2C)c(C)c1 +Cc1ccc2nc(NC(=O)CSc3nc(N)cc(=O)[nH]3)sc2c1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)N(C)CC1CC1 +Cc1nn(C)c(C)c1-c1cc(C(=O)N(C)Cc2ccc(F)cc2)[nH]n1 +CC(C)(C)C(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +CCn1cnnc1CNC(=O)N(C)CC(C)C(=O)OC +CN(CCOc1ccccc1Cl)Cc1nc(N)nc(N(C)C)n1 +CCC(Sc1ccc(Cl)cc1)C(=O)NCc1cccnc1 +CCOC(=O)N(C)CC(=O)NC(C)C(=O)NC(C)(C)C +O=C(C1CC1)N1CCN(Cc2noc3ccccc23)CC1 +NC(=O)C1Cc2ccccc2CN1CCSc1ccccc1F +NS(=O)(=O)c1ccc(NC(=O)c2ccco2)cc1 +COc1cc(CNC(=O)c2cccnc2)ccc1OCc1cccnc1 +O=C(Nc1ccc(F)c(S(=O)(=O)NC2CC2)c1)c1cccs1 +Cc1c(C(=O)NCc2ccco2)cnn1-c1ccncc1 +CC(=O)c1ccc(C(=O)N(C)c2cccc3ncccc23)cc1 +COc1ccc(S(=O)(=O)NCC2CCCC2)c(C)c1 +COC(=O)CC1CCC(n2ncc3c2CCC(O)C3)CC1 +Cc1nc(Cc2ccccc2)sc1C(=O)N1CCNC(=O)C1 +Cc1nc(CN(C)CCn2ccc(N)n2)cs1 +Cc1cccc(CC(=O)NCCS(N)(=O)=O)c1 +Cc1cccc(-c2ccnc3c(C(=O)NCc4ccccc4)cnn23)c1 +CCn1cnnc1CNC(=O)c1ccc(C(C)C)cc1 +COc1ccccc1-c1cnc(CSc2n[nH]c(=O)n2C)o1 +Cc1cc(C)c(C(=O)NCc2cc(=O)[nH]c3ccccc23)c(C)c1 +O=c1oc2ccc(Cl)cc2n1Cc1nnc(-c2ccccc2)o1 +CC(=O)Nc1ccc(NC(=O)Cn2ccccc2=O)cc1 +COCCOC(=O)c1c(C)nn(Cc2ccccc2Cl)c1C +O=C(CCc1c(Cl)cccc1Cl)N1Cc2cncnc2C1 +CNC(=O)c1cccc(NCC(=O)NC2(C#N)CCCCC2)c1C +COc1cccc(OC)c1OCC(=O)N(C)CCO +COC(=O)CCNS(=O)(=O)c1ccc(C(C)(C)C)cc1 +CC(C)c1noc(CCNC(=O)NC2c3ccccc3CC2O)n1 +COc1cccc(NC(=O)COc2cccc(C(C)O)c2)c1 +CC(=O)Nc1cccc(OCCNC(=O)NCc2sccc2C)c1 +COC(=O)c1ccc2ncc3c(c2c1)NCCNC3=O +CCc1onc(C)c1NC(=O)CCNC(=O)c1n[nH]c2ccccc12 +CC(C)CNC(=O)CSc1ccc(C(=O)C2CC2)cc1 +CCOC(=O)c1[nH]c(C)c(CCC(=O)Nc2ncccc2C)c1C +O=C(c1cccc2c1OCO2)N1CCCC(n2cccn2)C1 +CC(=O)c1ccc2c(c1)N(CCCc1ccccc1)C(=O)CO2 +CC(=O)Nc1ccc(F)c(C(=O)Nc2ccc(C(N)=O)cc2)c1 +C=CCOc1cccc(NC(=O)c2cc(C)nc3c2c(=O)[nH]n3C)c1 +CC(C)Oc1ccc(CNC(=O)c2ccc3c(c2)CCC(=O)N3)cn1 +Cc1cc(Br)cnc1NC(=O)OC(C)(C)C +CCN(CC1CC1)C(=O)c1cc(=O)[nH]c2ccc(Br)cc12 +CCOC1CCCN(c2cc(C)nc3nc(C(F)(F)F)nn23)C1 +Cc1noc(CCC(=O)NC(C)c2cccc3ccccc23)n1 +C=CCNC(=O)c1cc2nccc(-c3cccs3)n2n1 +Cc1nn(C)c(C)c1CN(C)S(=O)(=O)c1ccc(Cl)cc1 +Cc1ccsc1C(=O)N1CCC(n2cc(C(C)(C)O)nn2)CC1 +O=C(OC1CCCC1n1cccn1)c1cncc2ccccc12 +COc1ccc(C)cc1NCC(O)c1ccccc1F +COc1ccc(-c2ccc(CO)c(=O)n2CCC(C)C)cc1 +O=c1[nH]ncc(NCCc2c(F)cccc2F)c1Cl +Cc1ccc(C#N)c(NC(CO)c2ccccc2)c1 +Cc1nn(C2CCCCC2)c2c1C(c1nc3ccccc3[nH]1)CC(=O)N2 +CC(C)COCCC(=O)N1CCc2cc(F)ccc2C1 +CC(NC(=O)c1ccc(NC(=O)c2ccco2)cc1)c1ccccn1 +CC(C)S(=O)(=O)c1ccccc1C(=O)N1CCOC(C)(C)C1 +NC(=O)c1nn(-c2ccc(F)cc2F)c2c1C(=O)CCC2 +CCCOc1ccc(C(C)NC(=O)C2CCC2)cc1OC +CC(=O)OC1CCC(C)C2(C)C(OC(C)=O)c3c(C)coc3C(=O)C12 +CCc1ncc(C(=O)NC2CCCN(Cc3ccccc3)C2=O)s1 +Cc1cc(C(=O)CSc2nncn2C)c(C)n1C(C)C +O=C(Nc1ccc(F)c(Cl)c1)C(Cc1ccccc1)n1cnnn1 +COC(=O)C1C2CCC(C2)C1NC(=O)c1cccc(OC)c1F +C#CCN1CCN(C(=O)NCc2ccc(OC)nc2)CC1 +O=C(CCc1ncc(-c2ccc(F)cc2F)o1)Nc1cc[nH]n1 +Cc1ccc(-n2cc(C(=O)NC(C)CO)nn2)cc1 +Cc1cc(Cl)ccc1NC(=O)c1cn(CC(=O)N(C)C)nn1 +CC(=O)N(C)Cc1cccc(NC(=O)N(C)Cc2ccccc2F)c1 +COC(=O)CCC(=O)Nc1ncc(Cc2ccc(F)cc2F)s1 +Cc1cc(-c2cc(CO)nn2CCCO)ccc1Cl +Cc1cccc(OCCNC(=O)CS(=O)(=O)c2nccs2)c1 +COCC(C)N1CCN(C(=O)C(C)NC(=O)c2cccs2)CC1 +COc1ccc(C)cc1C(=O)Cn1cnc2sc(C)cc2c1=O +O=S(=O)(c1cccs1)N1CCOc2ccc(F)cc21 +O=C1CN(C(=O)CCSc2ccccc2)CCN1 +O=c1cc(CSc2n[nH]c(=O)n2C2CC2)c2ccc(O)cc2o1 +O=c1c2ccccc2[nH]c2ccc(Br)cc12 +CCCNC(=O)c1cccc(NC(=O)N2CCCC(OCC)C2)c1 +Cc1ccc2c(cnn2CCC(=O)NCCCO)c1 +Cc1cnc(C)c(-c2coc3ccccc3c2=O)n1 +CCc1ccc2c(c1N)C1(CCOCC1)S(=O)(=O)N2C +CC(=O)Nc1nc(CC(=O)Nc2cccc(F)c2)cs1 +Cc1ccc(CN2CCC(c3nnc(-c4ccncc4)o3)C2)cc1 +COc1ccccc1C(=O)NCC(=O)c1ccc2c(c1)OCO2 +COC(=O)C1CCN(C(=O)NCc2cccc(Cl)c2)CC1 +CCNC(=O)CNC(=O)c1ccccc1OCC +CC(NC(=O)CSc1ncn[nH]1)C(=O)NC(C)(C)C +COC(=O)C(C)NC(=O)C1CNCCN1S(C)(=O)=O +CCOc1ccc(OC(=O)CCn2ccccc2=O)cc1 +O=C1CC2(CCN(C(=O)Nc3cccc4ccccc34)CC2)CN1 +COC(=O)Cn1cc(Nc2ccnc(-c3ccccc3)n2)cn1 +Cc1ccc(OCC(=O)Nc2ccc(OC(F)(F)F)cc2)nc1 +Brc1ccccc1Cn1nnc(-c2cccnc2)n1 +Cc1cccc(OC(C)C(=O)NCCc2c(O)n[nH]c2C)c1 +COC(=O)c1cccc(COC(=O)c2cccc(C)n2)c1 +CC(OC(=O)c1n[nH]c2ccccc12)C(=O)NCc1ccco1 +CNC(=O)NCC(=O)NCC(C)(C)c1cccc(C)c1 +COCCn1c2c(ccc1=O)CC(NS(C)(=O)=O)CC2 +Nc1cc(F)ccc1CNc1ccc(Cl)cc1 +N#Cc1ccccc1OCc1cccc2cccnc12 +CC(C)(O)CS(=O)(=O)c1cc2c(cc1Cl)OCCO2 +Cc1nn(C)c(C)c1NC(=O)c1cc(F)c(F)cc1Cl +O=C(Nc1ccc(O)c(C(F)(F)F)c1)c1cccc(-n2ccnc2)n1 +CCCNC(=O)CNC(=O)NCCc1cccs1 +CC1Oc2cc(Cl)c(N)c(Cl)c2N(C)C1=O +COc1ncnc2c1CN(CC(=O)N1CCNC(=O)C1)CC2 +Cc1cc(=O)c2ccccc2n1CC(=O)NCc1ccccc1 +CC(=O)c1c[nH]c(C(=O)NCC2(c3ccc(F)cc3F)CC2)c1 +CC(C)(C)CC(=O)Nc1ccc2c(c1)N(S(N)(=O)=O)CC2 +Cc1cccc(CCC(=O)Nc2cccc3cn[nH]c23)c1 +CN(CC(=O)OC1CCCCC1)S(=O)(=O)c1ccccc1C#N +O=C(NCCO)c1ccc(-c2nc3ccccc3s2)s1 +N#Cc1ncn(CC(=O)c2sccc2Br)n1 +COCc1ccc(C(=O)Nc2cc(NC(=O)C(C)C)ccc2C)o1 +COc1ccc(Cc2nnc(SC(C)C#N)o2)cc1 +CCc1ccc(NC(=O)N2CCC(OCC(C)C)CC2)cc1 +Cc1nc(C(=O)Nc2ccc(CC(=O)N(C)c3ccccc3)cc2)c[nH]1 +Cc1ccc(-c2n[nH]c(=NC(=O)Cc3cn4ccsc4n3)[nH]2)s1 +O=C(NCc1ccc(Br)cc1Cl)NCC1CCCO1 +CC1CC(C)CN(C(=O)c2cc(F)cc(F)c2)C1 +Cc1ccc(NC(=O)CCn2cc(Cl)cn2)nc1 +COc1ccc(-n2nnc(C#N)c2-c2ccccc2F)cc1 +C=Cc1nc2c(C(=O)OC)ccc(-c3cccs3)n2n1 +COC(=O)c1cccc(S(=O)(=O)Oc2ccc(F)cc2F)c1C +CC(C)CCNc1ncnc(NCc2ccc(Cl)cc2)c1N +CN(CCN1CCOCC1)Cc1cnc(-c2cccnc2)s1 +Cc1ccc(C(=O)N2CCCC2c2ccncc2)cc1S(N)(=O)=O +O=C(NC1CCC(C(F)(F)F)CC1)c1ccsc1 +CC(C)N(CCO)c1ccc2scnc2c1N +C=CCOc1ccc(C(=O)Nc2ccc3c(c2)COC3)cc1OC +O=C(COc1ccccc1)NCC(=O)N1CCCCC1 +Cn1ccc(NC(=O)c2ccc(S(=O)(=O)N3CCCCC3)cc2)n1 +COc1cc(Br)c(N)c(Br)c1 +CC(C)CCNc1ncnc(Oc2cccnc2)c1N +CC(C)Oc1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cn1 +CSc1nc(C)c(CCC(=O)Nc2ccncc2)c(=O)[nH]1 +COCCOCC(=O)N1CCOC(Cc2cccc(F)c2)C1 +Cc1cc(C(=O)OC(C)C)ccc1N1CCNC1=O +CN(CC(=O)NC1CC1)C(=O)c1ccnc(OCc2ccccc2)c1 +Cc1nccc(-c2cc(-c3ccc(Cl)cc3Cl)no2)n1 +Cc1cccc(NS(=O)(=O)c2cc(F)ccc2F)c1 +CCc1nnc(SCc2nc(-c3cccs3)oc2C)n(N)c1=O +COCC(C)(O)CNS(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1nc(-c2c(C)c(-c3ccc(F)cc3)nc(N)c2C#N)c[nH]1 +COC(=O)c1cc(C(C)C)sc1NC(=O)c1cc(C)on1 +CCCCN(C)C(=O)Cn1nnc2ccccc2c1=O +Cc1cc(NC(=O)C(C)(C)Oc2ccc(Cl)cc2)no1 +COCCNC(=O)CN(c1cccc(C)c1C)S(C)(=O)=O +CC(=O)C(NC(=O)CSc1cccc(Br)c1)C(C)C +N#CCc1cn2cc(Cl)cc(Br)c2n1 +COc1cccc2c1OCC(Cc1cnc(-n3cnnc3)c(C)c1)C2 +CC(C)(C)OC(=O)NC(C)(C)C(=O)N1CCc2cc(F)ccc2C1 +COC(=O)CC1CCN(C(=O)c2ccc(C)cc2)CC1 +COc1ccc(F)cc1NC(=O)c1sc2ncn(C)c(=O)c2c1C +Cn1cc(C(=O)N2CCC(c3ccc(C(F)(F)F)cc3)CC2)cn1 +O=C(CCc1nccs1)N1CCC(C(O)c2ccccc2)CC1 +O=C(Nc1ccc(F)c(F)c1)c1cccc(OCC(F)F)n1 +COc1ccc(C(C)NC(=O)c2ccc(NC(C)=O)cc2)cc1F +CC(Cn1cncn1)NC(=O)c1cnoc1-c1ccccc1 +CC1CCN(CC(=O)Nc2nccs2)c2ccccc21 +O=C(COc1cccc(N2CCCC2=O)c1)Nc1cccc(F)c1 +O=C(Nc1nccs1)c1nccnc1-c1nc2ccccc2s1 +Cc1csc(SCC(=O)Nc2nc3ccccc3s2)n1 +CCCN(Cc1ccc(C#N)cc1)C(=O)Nc1nccs1 +O=C(NCCc1nc(-c2ccc(Cl)cc2)no1)C1CC=CC1 +CC1Cc2cc(C(=O)CO)ccc2N1S(C)(=O)=O +CCc1ccc(-c2nn(-c3ccccc3)cc2C(=O)N(C)C)cc1 +Cc1ccc(C(C)N(C)C(=O)CN(C)S(C)(=O)=O)cc1 +Cc1ccc(C(=O)N(C)C(C)c2ccc(S(C)(=O)=O)cc2)c(=O)[nH]1 +COc1cccc(CNC(=O)c2nnn(-c3ccc(F)cc3)n2)c1 +CCCCn1nc(CO)cc1-c1cccc(OC)c1 +CC(C)c1nc2ccc(Br)cn2c1CO +COc1ccc(CNC(=O)CCc2cccc3[nH]ccc23)c(OC)c1 +NC(=O)c1cccc(OC(=O)c2csc(-c3ccsc3)n2)c1 +NC(=O)c1ccc(OCC(=O)Nc2ccc(F)c(F)c2)cc1 +COc1cc(NC(=O)N2CCCC3CCCC32)ncn1 +CCOC(=O)N1CCN(C(=O)c2ccc(-n3nnnc3C)cc2)CC1 +C=CCn1c(SCc2cnn(C)c2)nnc1-c1ccccn1 +CC(Oc1ccccc1Cl)C(=O)Nc1cc(-n2cccn2)ncn1 +Cc1cnc(CNC(=O)c2nn(C)cc2Cl)cn1 +Cc1nnsc1C(=O)NC(Cn1cccn1)C(C)(C)C +CCOC(=O)C(C)(C)NC(=O)c1ccc(F)c(COC)c1 +CCCCc1nnc(SCC(=O)N(C)c2ccccc2)n1N +CC(C)c1ccccc1NC(=O)c1ccc(F)cc1-n1cnnn1 +Nc1ccc(-c2csc(CC(=O)c3cccnc3)n2)cc1 +COCC(NC(=O)c1coc(-c2ccccc2)n1)C(N)=O +CSc1cc2c(cc1N)C(=O)c1cc(F)ccc1-2 +N#Cc1ccccc1N1CCN(C2CCN(c3ccccc3)C2=O)CC1 +COc1ccc(C)cc1CN(C)C(=O)c1cnc(-c2ccccc2)nc1 +Cc1ccc(N2CC(C(=O)NCCn3ncccc3=O)CC2=O)cc1 +O=C(COc1ccc2ccc(=O)oc2c1)NC1CC1 +CNC(=O)c1nc(CN2CCN(c3ccccc3OC)C(=O)C2)no1 +CC1CN(C(=O)c2ccc(C(C)C)cc2)CC(C)O1 +O=C(NCCC(=O)N1CCc2sccc2C1)Nc1ccccc1 +Cc1n[nH]cc1CN(CCC#N)CCC(F)(F)F +O=C(Nc1nnc(Cc2cccs2)o1)c1ccccc1 +CC1CN(C(=O)CCc2cnn(-c3ccccc3)c2)c2ccccc21 +CC(=O)Nc1ccc(S(=O)(=O)NC2CCc3ccccc32)cc1 +COC(=O)C(C)Sc1nc2ccccc2c(=O)n1C +Cc1nc(N(C)C)ncc1C(=O)NCC(CO)Cc1cccs1 +CC(C)c1nn(-c2ccccc2)cc1CN(C)C(C)CC#N +Cc1nccn1-c1ncccc1NC(=O)c1c[nH]c2cccc(F)c12 +COc1ccc(C)cc1Nc1ccnc2c1c(=O)n(C)c(=O)n2C +Cc1cc(Br)ccc1OCC(=O)NCC1CCCO1 +CCCc1noc(CN2CCN(c3cnccn3)CC2)n1 +O=C(c1ccco1)N(CC1CCCO1)c1nc2ccccc2s1 +O=C(c1ccc(Cn2cncn2)cc1)N1CCCCc2ccccc21 +Cc1cc(C)c(S(=O)(=O)N2CCCC(O)C2)cc1C +CCOc1ccc(C(=O)N2C(C)COCC2C)cc1OC +CNC(=O)CN1CCN(C(=O)C2CC(=O)N(C(C)C)C2)CC1 +CC(=O)NCC(=O)N1CCc2[nH]nc(-c3cccc4ccccc34)c2C1 +Cc1cc(C)cc(OC(C)C(=O)Nc2cccnc2)c1 +O=C(CCOCC(F)(F)F)Nc1cc(Cl)ccc1F +CCOc1ccccc1C(CC(=O)NC1CCCCC1)NC(C)=O +Cc1nc(C)c(C(=O)NCC(C)c2nc(-c3ccccc3)no2)s1 +COc1ccnc(NC(=O)c2cccnc2NC(C)C)c1 +CCc1noc(Cn2c(-c3ccccn3)noc2=O)n1 +Cc1nn(C)c2[nH]nc(NC(=O)Cc3cn4ccsc4n3)c12 +Nc1cnccc1NC(=O)c1cc(Cl)ccc1F +Cc1cccc(S(=O)(=O)NCCc2nc3c(F)cccc3n2C)c1 +CC(NC(=O)C1CCCCN1C(=O)c1cccs1)c1ccncc1 +O=C(NCc1cccc(O)c1)c1cc(Br)cn1C1CC1 +CCOC(=O)Nc1ccc(NCc2cccn2C)cc1 +COCc1nc(N2CCOCC2)nc2c1CCCC2 +COCC(=O)Nc1ccc(OC(F)F)c(Cl)c1 +Nc1ccnc(CNC(=O)c2cc(C3CCCCC3)n[nH]2)n1 +COc1ccccc1NC(=O)c1cnc2[nH]c(C(C)=O)cc2c1 +COc1ccc(C(=O)N(CC(F)(F)F)C2CCOCC2)cc1OC +CCCc1noc(COc2ccc(C(N)=O)cc2)n1 +Fc1ccccc1Oc1ncccc1CNc1cnccn1 +Cc1nnc(NC(=O)C(c2ccccc2)c2ccccc2)s1 +CCCn1nccc1NC(=O)N1CCCC1C(=O)NCc1ccco1 +CCCCc1nc(-c2ccc(OS(C)(=O)=O)cc2)no1 +Cc1ccc(OCc2cc(N)cc3c2OCOC3)cc1 +COC(=O)c1[nH]c(C)c(C(=O)COc2cccc(C)c2)c1C +Cc1ccc(CNC(=O)CCC(O)c2ccc(C)cc2)cc1 +Cc1nc(C)c(C(=O)OCc2cc(-c3ccccc3F)on2)s1 +CC1=Nc2ncnn2C(=O)C1CCC(=O)Nc1cc(Cl)ccc1C +CCS(=O)(=O)N1CCC(C(=O)N2CCCCCC2)CC1 +Cc1cccc(N2CCN(c3nn4c(=O)cc(C)nc4s3)CC2)c1 +Nc1ccccc1C(=O)Oc1cccc2cccnc12 +CCOc1c(OC)cccc1-c1nc2cc(N)ccc2[nH]1 +Cc1cc(NC(=O)NCCc2ccc3c(c2)OCO3)no1 +Cc1cccc(N2CCN(C(=O)c3ccnc(-n4ccnc4)c3)CC2)c1 +COc1ccc(Cc2nc3ccccc3n2CCO)cc1OC +Cn1ccnc1SCC(=O)N(CCC#N)CCC#N +Cc1noc(C)c1CCCNC(=O)Nc1cccc(OC(F)F)c1 +N#Cc1ncn(CCCc2nc(-c3cccc(C(F)(F)F)c3)no2)n1 +CC(C)COCCC(=O)Nc1cc(C#N)ccc1Cl +CCOC1CC1C(=O)N1CC(C)C(N2CCOCC2)C1 +Cc1cccc(C)c1Oc1ncccc1CNCc1ccccn1 +O=S(=O)(c1cccnc1)N1CC(OCC2CC2)C2OCCCC21 +CN(C)C(=O)Sc1cccc(NC(=O)CC2CCCC2)c1 +O=C(Nc1cnc(N2CCOCC2)nc1)c1cccc2ccccc12 +CN(CCc1ccccn1)C(=O)c1cn(C)nc1C(F)(F)F +O=C(NCCOc1ccccc1)NCCc1cn2ccccc2n1 +COC(=O)C(C)CN(C)C(=O)c1ccc(Cn2nc(C)cc2C)cc1 +CC(C)NC(=O)CNC(=O)c1cc(NC(=O)c2ccccc2)n(C)n1 +O=C(OC1CCCC1)c1ccc(Cn2ccccc2=O)o1 +CSc1nsc(SCC(=O)NC(C)c2ccccc2)n1 +COc1cccc(-c2n[nH]c(-c3ccncc3)n2)c1 +Cc1ccc(NC(=O)NCC(O)C2CC2)cc1Cl +Cc1cc(C(C)NC(=O)N2CCN(C(=O)C3CCCO3)CC2)c(C)o1 +N#CCc1cnc2c(Cl)cc(C(F)(F)F)cn12 +COc1ccc(C(=O)NCc2ccccc2Cl)cc1OC +CC(C)COC(C)C(=O)Nc1ccc(N)cc1Cl +CC1CCN(C(=O)C2CN(C(=O)c3cnccn3)C2)CC1 +CCC(NC(=O)c1ccccn1)c1ccc(Cl)cc1 +Cc1ccc(CCNC(=O)NCC2CN3CCCCC3CO2)c(C)c1 +COc1ccccc1C(=O)Nc1ccc2nc[nH]c2c1 +CCNC(=O)c1csc(COc2ccccc2Cl)n1 +CC1C(=O)N(c2ccccc2F)CCN1C(=O)c1ccco1 +CC(=O)c1ccc(OC(C)C(=O)Nc2ccccc2)cc1 +Cc1cc(-c2cnc(N3CCCCC3)nc2-c2ccoc2C)on1 +CC(C)c1ccc2[nH]c3nc(SCC(=O)NC4CC4)nnc3c2c1 +CCOc1cccc(NC(=O)c2cnc(C)cn2)n1 +Cc1cc(C)c(-c2cc(CO)nn2CC#N)c(C)c1 +O=C(Nc1ccc(C(=O)N2CCCCC2)cc1)c1cccc(Cl)c1 +CC(C)n1cnnc1CNC(=O)CCc1cnn(-c2ccccc2)c1 +Cc1ncccc1C(=O)Nc1ccccc1S(=O)(=O)N1CCCC1 +N#Cc1ccsc1NCc1ccc(O)c(Cl)c1 +Nc1ncnc(Nc2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1 +CC(C)NC(=O)C1CCN(C(=O)C2CC(=O)N(C(C)(C)C)C2)CC1 +COc1ccc(CNc2ccc(S(N)(=O)=O)cn2)cc1 +Cn1nc(CNS(=O)(=O)c2ccccc2F)cc1-c1ccccn1 +Cn1cc(C(=O)N2CC3CCC(C2)N(CC2CCC2)C3=O)cn1 +CC(=O)Nc1ccc(OCC(O)CSc2ccc(C)cc2C)cc1 +COc1cccc(OC)c1-c1nc(C)ccc1C#N +Nc1ccc2ccnc(Nc3cccc(F)c3)c2c1 +O=C(Nc1ccc2c(c1)OCCO2)C1CC=CCC1 +CN(C)C(C(=O)NCCn1cccc1)c1ccc(F)cc1 +COC(=O)c1ccccc1NC(=O)CSc1nc(C2CC2)n[nH]1 +COCC(=O)Nc1ccccc1C(=O)Nc1cccc(Cl)c1 +CC(CC#N)N1CCN(C(=O)CC(F)(F)F)CC1 +CN(C(=O)c1cccs1)c1ccccc1C(=O)NC1CC1 +Cc1ccc(CNC(=O)c2cnc(C)nc2N)cc1 +O=C(N=c1[nH]c2ccccc2[nH]1)c1ccccc1-n1cnnn1 +CCOc1ncccc1CNc1cc(CC)nc2ccnn12 +Fc1cccc2c1C(c1cnccc1Cl)NCC2 +CC(C)N(CC(N)=O)S(=O)(=O)c1ccc(F)c(Cl)c1 +COc1cccc(Cc2cnc(NC(=O)C3CCC3)s2)c1 +Nc1ccccc1OCC1COc2ccccc2O1 +COc1cccc(-c2csc(NC(=O)c3cnccn3)n2)c1 +N#Cc1cc(F)ccc1NC(=O)NCc1cn(-c2ccccc2)nn1 +CNC(=O)CN1CCN(C(=O)c2[nH]nc(C)c2Br)CC1 +CCN1C(=O)NC(c2cccnc2)C(C(=O)OCC(C)C)=C1C +CCCS(=O)(=O)NCc1nnc(C(=O)Nc2ccccc2)s1 +CC(C)COc1nc(-n2cc(Cl)cn2)ccc1N +COC(=O)c1ccc(Cn2c(C)nc3cccnc32)cc1 +CCOc1cccc2c1CCNC2C(O)c1ccc(C)cc1 +N#Cc1ccc(OC(=O)CCCNC(=O)c2ccc(F)cc2)cc1 +COC(=O)Cn1c(CNC(=O)c2ccc(C)cc2)nc2ccccc21 +Cc1cccc(OCCCCn2c(=O)oc(=O)c3ccccc32)c1 +Cc1ccc(-c2nc(CNC(=O)CC(F)(F)F)no2)cc1 +CC(C)(C)n1ncc2c1CCCC2NC(=O)c1ccc(=O)[nH]c1 +Cc1n[nH]c(C)c1N1CCN(C(=O)c2cc(-c3ccco3)n[nH]2)CC1 +O=c1c2c3c(sc2nc2n1CCCCC2)CCCC3 +COCc1ccc(Cn2c(=O)[nH]c3ccccc3c2=O)cc1 +Cc1nccc(-c2cccc(NCc3nc(CC(C)C)no3)c2)n1 +CCN(CCO)C(=O)C(C)Sc1ccc(OC)cc1 +N#CCCn1ncc2c(N3CCCC3c3cccc(F)c3)ncnc21 +Cc1nn(C)c(C)c1OC(=O)CSc1ccccc1 +CCCc1cc(=O)nc(N=c2nc(C)c3ccccc3[nH]2)[nH]1 +Nc1ccc(NCc2ccccc2Cl)c(F)c1 +CN(C)C(=O)Cc1ccc(NC(=O)c2ccco2)cc1 +COC(=O)c1ccc(Cn2ccnc2Cc2ccccc2N)cc1 +CCN(CC)C(=O)N1CCN(C(=O)c2ccccc2O)CC1 +CC(=O)N1CCN(C(=O)CC(C)c2ccccc2)CC1 +Nc1ccc(F)c(NC(=O)CCn2cnc3ccccc32)c1 +CCOC(=O)C1=C(COC(=O)c2ccco2)NC(=O)NC1C +CCC(OC)C(=O)NCc1nc(-c2ccsc2)no1 +COC(=O)C(CC(C)C)NC(=O)c1c(-c2ccccc2)noc1C +COc1cc2[nH]c(=O)n(CC3CCCO3)c(=O)c2cc1OC +CCC1CCCCN1C(=O)Cc1ccccc1OC +Cc1nn(C)c(C)c1-c1cc(C(=O)OC2CCCCC2)[nH]n1 +Nc1ccc(C(=O)N2CCC(c3ccc4ccccc4c3)C(O)C2)cn1 +O=C(NCc1ccc2[nH]c(=O)[nH]c2c1)c1cccc(Cl)c1 +Cn1c(C(=O)Nc2cccc(C(N)=O)c2)cc2ccc(F)cc21 +Cc1cc(C(=O)NCc2cc(-c3ccco3)n(C)n2)no1 +Cc1ccc(-n2nc(C(=O)N3CCOCC3)cc2N)c(C)c1 +Cc1cc(-c2nnc(NC(C)C)s2)c(C)s1 +CC1CCN(S(=O)(=O)NC(C)Cc2ccco2)CC1 +Cc1nc2ccc(C(=O)NCc3snnc3C(C)C)cc2nc1C +COC(=O)c1c(C)[nH]c(C(=O)C(C)Nc2ccccc2OC)c1C +COc1ccccc1C1(CNc2ncc(S(N)(=O)=O)s2)CC1 +COC(=O)Cc1csc(NC(=O)c2csc(C)n2)n1 +CNC(=O)c1cccc(NC(=O)c2cccc(OCC(F)F)n2)n1 +COc1cc(CNc2cn[nH]c(=O)c2Cl)ccc1OC(F)F +Cc1ccc(N2CC(C(=O)N(C)CC(C)(C)O)CCC2=O)cc1C +CS(=O)(=O)NCCNC(=O)COC1CCCCC1 +CC(C)(O)CCc1cccc(C(=O)NC2CCCc3nccnc32)c1 +O=C(Cn1cnnn1)N1CCN(CC=Cc2ccccc2)CC1 +CC(c1ccccc1)N1CC(C(=O)NCC(C)(C)C(N)=O)CC1=O +CCC(C)n1nccc1NC(=O)C(C)Oc1cccc(F)c1 +CCCCN(Cc1cccs1)C(=O)Cn1c(=O)oc2ccccc21 +CCOc1ccc(NC(=O)N2CCCC2c2nc(C)no2)cc1 +CNc1cccc(NS(=O)(=O)c2ccc(C)cc2)c1 +NC(=O)COC(=O)c1c2c(nc3ccccc13)CCC2 +CC1CCc2c(sc(NC(=O)Cc3cccc(F)c3)c2C(N)=O)C1 +COc1cc(C)c(S(=O)(=O)N2CC(C)OCC2C)cc1OC +c1cn2nc(N3CCCC4(C3)OCCO4)ccc2n1 +CC(Cc1ccc(Br)cc1)NC(=O)c1nonc1N +CN(C)S(=O)(=O)c1ccc(CNC(=O)C(C)(C)C)s1 +Cn1cc(-c2cn3cc(N)ccc3n2)c2ccccc21 +N#CCCN(CCC(F)(F)F)S(=O)(=O)c1ccc(F)c(F)c1 +CN(CC(=O)NC(C)(C)C)C(=O)c1ccsc1 +C=CCn1c(SC(C)C(N)=O)nnc1-c1ccoc1C +CN(Cc1nnc2ccccn12)c1nccc2c1C(=O)OC2(C)C +CNC(=O)NC(C)(C)C(=O)Nc1cc(C)ccn1 +Cc1occc1C(=O)NCCc1cnn(-c2ccccc2)c1 +COc1ccc(NC(=O)NCC2Cc3ccccc3O2)cn1 +CCCNC(=O)CNS(=O)(=O)c1cccs1 +COc1ccccc1CNC(=O)CCSc1nnc(C)n1N +COc1cc(C)c(C(C)NC(=O)C(C)n2cncn2)cc1OC +Cc1ccc(Oc2ncnc(N3CCCC3)c2N)cc1 +CNC(=O)c1ccc(NC(=O)COc2cccc(OC)c2)cc1Cl +COCC1CCN(c2cncc(Br)c2)C1 +CCCc1nnc(NC(=O)CC(NC(N)=O)c2cccs2)s1 +CC(C)(NS(=O)(=O)c1cc(N)cc(F)c1)C(N)=O +CC(CNC(=O)c1cccc(C#N)c1)c1nc(-c2ccccc2)no1 +CC(=O)N(C)c1ccc(NC(=O)c2ccc3c(c2)OCCO3)cc1 +CNC(=O)c1ccccc1NC(=O)c1ccc(OC(F)F)cc1 +N#Cc1ccc(S(=O)(=O)NCc2ccccn2)cc1 +CC(C)Nc1ncnc2c1CCN(C(=O)CC1CCCC1)CC2 +CCc1nnc(CN2CCN(CCOC)C(=O)C2)n1C +Cn1c(-c2nc(C(=O)NC3CC3)cs2)cc2ccccc21 +CCOC(=O)CN(CC)C(=O)C1COc2ccccc2O1 +COC(=O)CSc1nnc(Cn2nnc3ccccc32)n1C +Cc1ccc(S(=O)(=O)N2CC3(COC3)C2)cc1 +O=S(=O)(NCCCn1cnc2ccccc21)c1ccccc1Cl +COc1ccnc(NC(=O)c2sc(C3CCCC3)nc2C)c1 +C=CCNC(=O)C(C)NCc1nnc2n1CCCC2C(F)(F)F +CCCCN(C)C(=O)Cn1c(=O)oc2cccc(N)c21 +Cc1nc(-c2ccc(NC(=O)N3CCOCC3C3CC3)cc2)cs1 +OCCn1ncc2c(N3CC=C(c4ccccc4)CC3)ncnc21 +CCN(CCC#N)C(=O)Nc1ccccc1Cl +Nc1nccnc1C(=O)NCCC(=O)N1CCOc2ccccc2C1 +Cc1cccc2nc(CSc3nc4ccccc4[nH]3)cn12 +Cc1csc(NC(=O)C2CCCN2c2ncnc3sccc23)n1 +CCc1ccccc1NC(=O)CN(C)C(=O)Cc1csc(C)n1 +C=CCN1CCN(C(=O)NCC)C(C(=O)NCc2ccccc2)C1 +COC(C)C(=O)Nc1cc(NC(C)=O)ccc1F +O=C(NCCc1cn2ccccc2n1)c1c[nH]c2cccc(F)c12 +CC(C)Cc1nnc2sc(Cc3cccnc3)nn12 +CC(NC(=O)Cc1csc(-c2cccnc2)n1)c1ccccc1 +c1nc(NCc2nccs2)cc(NCc2nccs2)n1 +COc1ccc(OC)c(Nc2ncnc(NCC3CCCO3)c2N)c1 +CCN1CCOC(CCNC(=O)c2cccc3[nH]c(C)nc23)C1 +CCOc1ccc(C(=O)Nc2nc3c(C)cccc3s2)nn1 +Cc1ccc(NCc2nsc(N(C)C)n2)cc1Br +COc1cc(C)c(C(=O)N2CCCC(CC(N)=O)C2)cc1OC +CN1C(=O)CCc2cc(C(=O)N(c3ccccn3)C3CCCC3)ccc21 +CCCOc1ncccc1CNC(=O)N1CCCC(C)CC1 +CCN(CC)C(=O)C1CCCCN1C(=O)c1cccs1 +Cc1ccc(C)c(-c2cncc(CN3CCOCC3)c2)c1 +Cc1ccc(-n2ccnc2S(C)(=O)=O)c(C)c1 +CC(N)C(=O)OCCc1ccc2c(c1)N(C)C(=O)C(C)O2 +COc1cc2ncnc(NCCN3CCOCC3)c2cc1OC +Cc1nnsc1CN(C)C(=O)CN1CCN(c2ncccn2)CC1 +COc1ccc2c(c1)CCNC2C(O)c1ccccc1F +CC1CC1C(=O)Nc1ccccc1NC(=O)N1CCCC1 +CN(Cc1nccn1C(F)F)C(=O)Cc1cccc(F)c1 +COc1ccc(S(=O)(=O)NCC(C)(C)N2CCOCC2)cc1C +CCn1ncc(Cl)c1C(=O)NC(C)c1ccccc1 +CN(C)S(=O)(=O)c1c(Cl)cc(Br)cc1Cl +CC(C)NC(=O)Nc1ccc(NC(=O)C2CCc3ccccc32)cc1 +Cc1ccc(C(=O)N2CCC3C2CC(=O)N3c2cccnc2)cc1F +CCOC(=O)c1cccc(NC(=O)Cn2nc3ccccn3c2=O)c1 +CC(O)CNC(=O)c1nn(-c2ccc(Cl)cc2)nc1CO +CCOc1ncccc1C(=O)N(C)Cc1ncc(C)c(OC)c1C +Cc1noc(C)c1CC(=O)OCC(=O)Nc1sccc1C#N +O=S(=O)(NCC#CCN1CCOCC1)c1ccccc1F +Cc1ccc2cc(CNc3cc(Cl)ccc3O)c(=O)[nH]c2c1 +COc1ccc(C(C)=O)c(OCC(=O)NC(C)c2ccccc2C)c1 +O=C(Nc1ccc2c(c1)COC2)N1CCN(c2ccc(F)cc2)CC1 +CCOC(=O)Nc1sc2c(c1C(N)=O)CCCCC2 +NC(=O)c1cccc(OC(=O)c2ncoc2-c2ccccc2Cl)c1 +CCOc1cc(C)c(C(O)CCC(=O)OC)cc1C +COCCn1c(=O)[nH]c(=O)c2c(-c3ccccc3OC)ccnc21 +CCCCn1nc(C(=O)Nc2ccc(C)cc2)ccc1=O +O=c1ccccn1Cc1noc(-c2ccccc2Cl)n1 +CC(C)N(C)C(=O)C1CC(=O)c2sc(NC(=O)C3CCC3)nc2C1 +Cc1cnc(NC(=O)c2ccccc2SCC(=O)NC(C)C)s1 +Cc1ccccc1NC(=O)C1CC(=O)N(Cc2ccccc2)C1 +Nc1cccc(Cn2cnc3cc4c(cc32)OCCO4)c1 +CCN(CC(=O)NC(C)(C)C)S(=O)(=O)c1cccc(C(C)=O)c1 +COc1ccc(OC)c(C2CCCN2C(=O)Cn2nc(C)nc2C)c1 +Cc1cc(NC(=O)CNC(=O)NC2CCCCC2)n(C(C)(C)C)n1 +O=C(Nc1cc(F)ccc1F)N1CCC(OCc2ccccc2)CC1 +COc1ccccc1C(C#N)N1CCC2(CC1)OCCO2 +Cc1csc(C2CN(Cc3cc4cc(F)ccc4o3)CCO2)n1 +CN(CCc1ccccc1)C(=O)CCn1cnc2ccccc2c1=O +COC(=O)C(C)C(NC(=O)C1CCC(C(N)=O)CC1)c1ccccc1 +COc1cc(Cl)ccc1S(=O)(=O)NCC(C)O +NC(=O)c1ccccc1OC(=O)Nc1ccccc1F +O=C(Cc1csc(-c2ccccn2)n1)N1CCc2sccc2C1 +CNC(=O)c1cccc(NC(=O)CNc2ccccc2C(N)=O)c1 +Cc1c(OCC(C)(C)CS(N)(=O)=O)nn2ncnc2c1C +NS(=O)(=O)c1ccc(Cl)c(C(=O)N2CCCC2)c1 +O=C1CC(C2NCCc3cc4ccc(O)cc4cc32)C1 +CCCn1c(SCc2ccc(-n3cccn3)cc2)n[nH]c1=O +O=C(C1CC1)N1CCCC(Cn2nc(-c3cccs3)ccc2=O)C1 +Cc1cc(Br)ccc1C(=O)NCC1CN(C)CCO1 +CCS(=O)(=O)c1ccccc1NCCS(N)(=O)=O +Cc1cc(NC(=O)CCc2ccc(C)o2)c2ncccc2c1 +Cc1ccc(Br)cc1S(=O)(=O)NCc1ccoc1 +Cc1ccc(N2CC(C(=O)Nc3cc(C)c(Cl)cn3)CC2=O)cc1 +N#Cc1ccc(C(=O)N(CC(F)(F)F)c2ccccn2)cc1 +CCNC(=O)NC1CCC(OC(=O)C=C(C)c2ccccc2F)CC1 +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1ccc(-n2ccnn2)cc1 +CCN(CC(=O)OCC1CCCN1C(N)=O)c1ccccc1 +COC(=O)c1cc(CN(C)C(=O)NC(C)C)oc1C +O=C(c1cc(C2CC2)on1)N1CCCC1c1nnc2ccccn12 +Cc1nc2cc(NC(=O)c3cccc4cn[nH]c34)ccc2o1 +Cc1ncsc1CN(C)CC(O)c1ccccc1 +O=C1CSc2ccc(NC(=O)NCC3CC=CCC3)cc2N1 +O=C(NCCNC(=O)C1CC1)c1cccc(-n2cccn2)n1 +CCCOCC(=O)Nc1ccc(NC(=O)CC)c(C)c1 +Cc1cc(N)nc(SCC(=O)Nc2ccc(F)c(F)c2)n1 +CCN(C)C(=O)c1cccc(OC(=O)Cc2c(F)cccc2F)c1 +COc1ccc(C(=O)N(CC(F)(F)F)C2CCCC2)cc1OC +CNC(=O)NCC(=O)NC1CCN(c2c(F)cccc2F)C1=O +CC1CCC(NC(=O)Nc2ccccc2C(=O)N2CCOCC2)CC1 +CCCN(Cc1ccsc1)C(=O)CC(C)(C)C +CCOc1ccc(CC(=O)N2CCCS2(=O)=O)cc1 +CCc1nnsc1C(=O)N1CC(CC)Oc2ccccc21 +N#CC1(NC(=O)Cc2ccc(O)cc2)CCCCC1 +COc1ccccc1CC(=O)NCc1cn2ccsc2n1 +COC(C)C(=O)Nc1ccccc1CN1CC(C)OC(C)C1 +CCCNC(=O)N1CCN(CC(=O)NCC)CC1 +COc1cccc(CNc2ccc(C)c(NC(C)=O)c2)c1OC +O=C(NCCCNC(=O)C1CCCCC1)c1cnc2ccoc2c1 +C#CCN1C(=O)C(Cc2ccccc2Cl)Oc2ccc(N)cc21 +COC(=O)c1[nH]c(C)cc1NC(=O)c1ccc2c(c1)CCN2C(C)=O +CC(Cn1cccn1)NS(=O)(=O)C1CN(C(=O)c2ccccc2)C1 +CCn1cc(NC(=O)c2cc(C)n(Cc3ccco3)c2C)cn1 +Cc1nn(C)cc1-c1cc(C(F)F)c2c(-c3ccccc3)noc2n1 +Cc1ccccc1CC(C)NC(=O)c1[nH]nc(C)c1Br +CC(O)CNC(=O)CSc1ccc(F)cc1F +O=C(c1ccc2cc[nH]c2c1)N1CCN(c2ncccc2Cl)CC1 +Cc1nnc(NC(=O)Cc2nc(-c3ccccc3)oc2C)s1 +CSc1nc(C2CCCC2)nc2c1c(=O)n(C)c(=O)n2C +O=C(Cn1ncccc1=O)NCc1ccc(F)cc1 +O=C(c1ccsc1)N1CCCC(c2cc(C(F)(F)F)[nH]n2)C1 +c1ccc(CCN2CCCC2c2nnc(-c3cnccn3)o2)cc1 +Cc1nccn1-c1ccccc1-c1nc2c([nH]1)CC(C)(C)CNC2=O +COC1CCCN(C(=O)C2CCCN(C(=O)Nc3ccccc3)C2)C1 +Cc1cc(C(=O)CNc2ccc(C#N)cc2)ccc1F +COC(=O)c1cccc(C(=O)NCc2ccc(C)cc2)c1 +CC(C)n1c(COc2ccccc2N)nc2cccnc21 +C=CCn1c(SCCC(N)=O)nnc1-c1ccc(Cl)cc1 +Cc1ccc(C(=O)C(C)C)cc1S(=O)(=O)N(C)C +c1ccc(CNCc2ncc(-c3cccnc3)s2)cc1 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)c1ccncc1F +CC(CC(=O)N1CCCS1(=O)=O)NC(=O)c1ccccc1 +Cc1nccc(N2CCC(c3[nH]ncc3-c3cccc(F)c3)CC2)n1 +COc1cc(C(=O)N(C)C2CC2)ccc1OCC(N)=O +CCOc1ccccc1-c1cn2ccc(Cl)c(N)c2n1 +Cn1c(=O)c2c(c3ccccc31)OC(=O)CC2c1ccc(F)cc1 +CCN(Cc1cccc(C)c1)C(=O)NCCC(=O)N1CCCCC1 +O=C(Nc1cccc(CN2CCCC2=O)c1)C1CCCO1 +N#CCCCSc1nnc(N2CCCCC2)n1-c1ccccc1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)N1CCOCC1C1CC1 +Cc1cc(C(=O)N2CCC(S(=O)(=O)c3ccccc3)C2)c(C)o1 +COc1ccnc(NCc2ccc(C(=O)N3CCCCC3)cc2)n1 +NC(=O)NCc1ccc(NC(=O)COc2ccccc2Cl)cc1 +CCN(C(=O)C(C)S(=O)(=O)c1ccc(C)c(C)c1)c1ccccc1 +CCC(C)NC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 +Cc1nc2cc(C(=O)NCC3CN(CC(C)C)CCO3)ccc2n1C +CCOC(CC)C(=O)NCc1cccc(N2CCCCC2=O)c1 +Cn1cc(C#N)cc1-c1nc(CC(N)=O)nn1-c1cccc2c1CCC2 +CCCC1CN(C(=O)C2CC(=O)Nc3cc(F)ccc32)CCO1 +CC(=O)c1ccc(NC(=O)c2nnn(-c3cc(C)cc(C)c3)c2N)cc1 +O=C(CCC(=O)c1ccc2c(c1)OCCO2)Nc1cn[nH]c1 +CCCc1cc(C(=O)NCCN2CCOCC2)[nH]n1 +O=C(Nc1ccc(Br)cc1)NC1CCCc2occc21 +CC1CCC(C)N1C(=O)c1cc(COc2ccccc2)[nH]n1 +Cn1cc(C(=O)NCc2ccccc2Cl)c(=O)c2cc(F)ccc21 +Cn1c(=O)c2c(ncn2CC(=O)c2ccc(F)cc2F)n(C)c1=O +CNC(=O)C(C)CN(C)C(=O)c1c[nH]nc1-c1ccccc1Cl +CCn1nc(C)c(Br)c1-c1nc(-c2ccccn2)no1 +CC(C)OC(=O)CSc1nnc(C2CCCCC2)o1 +COc1ccc(-c2ccc(=O)n(C)n2)c2ccc(C)nc12 +COc1cccc(C(=O)NCC(O)C2CCCCC2)c1OC +Cc1ccc(-n2cc(C)cn2)c(NCc2ccncc2)c1 +Cc1cc(NC(=O)c2ccc(OCc3nnnn3C(C)C)cc2)no1 +CCNc1ccc(S(=O)(=O)N2CCN(C)CC2)cn1 +O=C1CC(c2nc(C3CC3)no2)CN1c1cc(F)cc(F)c1 +Cn1cc(NC(=O)c2ccccc2F)c(C(N)=O)n1 +CC(C)C(=O)Nc1cccc(C(=O)n2cnc3ccccc32)c1 +O=C1CCC(COC(=O)c2ccc(-c3ccccc3)cc2)N1 +COc1ccc(CNC(=O)c2cc3cccn3cn2)cc1OC +CC(C)COc1cccc(CNC(=O)C2CCOCC2)c1 +O=C(COC(=O)c1ccc2ccccc2n1)c1ccc2c(c1)OCCO2 +CN(CCO)C(=O)CNS(=O)(=O)c1ccccc1 +CCCn1ccc(C(=O)Nc2cnn(CC(F)(F)F)c2)n1 +Cc1ccc(C(=O)N2CCN(C(=O)C3(c4ccccc4)CC3)CC2)cc1 +O=C(NCc1ccc2c(c1)OCO2)c1cc2cn[nH]c2cn1 +CCc1ccc(OCC(=O)Nc2nonc2C)cc1 +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)Nc1c(C)nn(C)c1C)O2 +Brc1ccc(-c2nc3[nH]ncn3n2)cc1 +COCCCN(Cc1ccccn1)S(C)(=O)=O +CC(=O)c1c(C)nc(C)nc1SCc1ccc(F)c(F)c1 +O=C(Cc1cccs1)N1CCC2C1CC(=O)N2c1cccnc1 +CN(C)C(=O)c1n[nH]c2c1CN(C(=O)Nc1cccc(F)c1)CC2 +CCc1nc(CNc2cc(Cl)ccc2C(=O)NC)no1 +C#CCS(=O)(=O)c1ccc(C(=O)OCCC)cc1 +Cc1ncccc1Oc1ncnc(-c2cc(N)nc3[nH]ccc23)c1C +O=C(c1cnc2ccccc2n1)N(Cc1ccsc1)Cc1ccco1 +CCCN(CC1CC1)C(=O)C1CCN(C(=O)c2cccs2)CC1 +CC1Cc2ccccc2N1C(=O)COC(=O)c1cc(F)ccc1F +CC1CCc2c(sc3ncnc(NCc4nnc5n4CCC5)c23)C1 +O=C(Nc1nc(C2CC2)cs1)c1cccnc1OCC(F)F +CCOC(=O)C(O)Cc1nnc2c(OC)cc(C)nn12 +CCCNC(=O)c1ccc(-c2cccc(OCC)c2)nc1N +O=C(NC1CC1)C1CNCc2cccc(Cl)c21 +Cc1cnn(CC2CN(CC(=O)Nc3sccc3C#N)CCO2)c1 +COc1cc2c(cc1F)C(c1ccncc1)NCC2 +Cc1nccn1-c1cc(CNC(=O)c2ccccn2)ccn1 +COc1ccc(F)cc1NC(=O)c1cccc2c1OC(C)C(=O)N2 +COC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)n1C +O=C(CN1CCCc2cc(F)ccc21)Nc1nccs1 +Cc1ccc(NC(=O)Nc2c(C)cccc2N)cc1 +O=C(NCCc1nc(-c2ccccn2)no1)C1CCOC1 +CNS(=O)(=O)c1cc(S(C)(=O)=O)ccc1Br +Cc1sc(NC(=O)NC(C)c2cccs2)c(C#N)c1C +NC(=O)c1cccc(NC(=O)NC(CO)c2ccccc2)c1 +O=C(NCc1ccc(Cn2cncn2)cc1)c1cnc2ccccc2n1 +COc1ccccc1NC(=O)Cc1nc(Cc2ccc(F)cc2)n[nH]1 +COc1ccc(CNC(=O)c2noc3c2CCc2ccccc2-3)cc1 +Cc1nn(-c2ccccc2)c(C)c1NS(=O)(=O)C(C)C +CCC(=O)N(C1CC1)C(C)C(=O)c1c(C)c(C(=O)OC)n(C)c1C +CCCn1c(SCCNS(C)(=O)=O)nc2cc(Cl)ccc21 +COc1cc(Br)c(C(C#N)N(C)C)cc1OC +Cc1ccc(Cl)c(OCn2nc(C)c(N)c2C)c1 +CN(C)C(=O)COc1cccc(CNc2ncccc2C#N)c1 +Cc1cccc(OCC(O)CNC(=O)c2cc(C(C)(C)C)nn2C)c1 +CCCN(CCC)C(=O)CSc1nc(C)nc2ccccc12 +O=C(Cc1ccc[nH]1)NCCNC(=O)c1cccs1 +CCS(=O)(=O)c1ccc(N2CCC(NC(=O)C3CC3)CC2)cc1 +CC(NC(=O)c1ccc(F)cc1)c1nc2ccccc2n1C +CC(NC(=O)c1cc(C(N)=O)cs1)c1ccccc1Cl +CC(C)(C)CC(=O)NCC1CN(Cc2ccccc2)CCO1 +c1coc(-c2nc(-c3ccc4c(c3)OCO4)no2)c1 +O=C(CNC(=O)c1ccncc1)NC1CCCc2ccccc21 +O=C(Cc1noc2ccccc12)N1Cc2cncnc2C1 +CCc1sc(C(=O)NC(C(N)=O)c2ccccc2)cc1C +C=CCN(Cc1ccc(OC)cc1)C(=O)Nc1ccc(OC)nc1 +COCCOCC1NCCc2ccc3ccccc3c21 +CCc1n[nH]c(NC(=O)c2ncncc2Cl)c1Br +COc1ccccc1N(CC(=O)NCc1ccncc1)S(C)(=O)=O +O=C(CC1CCCO1)Nc1cccn(Cc2ccccc2)c1=O +CC(C)CC1COCCN1CC(O)c1ccc(S(C)(=O)=O)cc1 +CC(=O)NCc1ccc(C(=O)NC2CCCC2)cc1 +CC(Sc1nc(N)cc(N)n1)C(=O)c1ccc(Cl)cc1 +Cc1ncsc1-c1nc(C2CCCN2C(=O)OC(C)(C)C)no1 +O=C1CCC2(CCCO2)CCN1Cc1cc(F)cc(C(F)(F)F)c1 +COc1cc2c(C(=O)N3CCOCC3)nccc2c(N)c1OC +C#Cc1cccc(NC(=O)c2cnn(Cc3ccccc3)c2CC)c1 +CCCOc1ncccc1CNC(=O)Cc1cccc(C)c1 +O=C(c1ccnnc1)N(Cc1cc(F)ccc1F)c1ccccc1 +Cc1ccc(F)cc1NC(=O)CSc1nnc2ccccn12 +O=C(NCCCOC1CCCCC1)c1ccc2c(c1)OCO2 +Cc1nn2c(N)c(-c3ccccc3)nnc2c1-c1ccccc1 +O=C(CSc1nc(=O)[nH]c2c1CCC2)Nc1ccccc1 +O=C(Nc1ccc(Cl)c(C(=O)NC2CC2)c1)c1cccs1 +O=C(c1cc(-c2ccc(F)cc2)n[nH]1)N1CC2CCCC2(CO)C1 +NC(=O)C1(CNC(=O)COc2cccc(Cl)c2)CCOCC1 +Cc1nc(-c2nc3c([nH]2)CC(C)(C)CNC3=O)nc2c1CCCC2 +Cc1nc(C)n(CC(=O)NC2C3CCCCC3C2c2ccccc2)n1 +CC(=O)N(C)Cc1cccc(NC(=O)C(C)(C)c2ccccc2F)c1 +O=C(c1cnn2cccnc12)N1CCCC1c1ccccc1Cl +CCC1COCCN1CCOc1ccccc1C#N +COC(=O)Cc1csc(NC(=O)c2c(F)cccc2Cl)n1 +CN(CC12CC3CC(CC(C3)C1)C2)C(=O)c1cnccn1 +c1ccc(COC2CCC3C2OCCN3Cc2ccncc2)nc1 +CCNC(=O)N1CCN(C(=O)c2cn(CC)nc2C(C)C)CC1 +C(=Cc1nn2c(Cc3ccccc3)nnc2s1)c1ccco1 +Cc1noc(CCC(=O)N2CCOc3ccccc32)n1 +CSc1ncccc1C(=O)N(C)CC(=O)Nc1ccc(Cl)cc1 +CCOc1ccc(C(C)NC(=O)c2cccc(C)n2)cc1OC +CCCNC(=O)CN1CCN(C(=O)Cc2ccccc2C)CC1 +CCC1Nc2cc(Br)ccc2NC1=O +Cc1cccc(NC(=O)N2CCOC(C)(c3cnn(C)c3)C2)c1Cl +CCc1noc(CC)c1CC(=O)N1CCCC2CCCC21 +O=C(c1ccc(COc2ccc(F)cc2)cc1)N1CCCC1 +CCNC(=O)c1ccc(NCC(=O)Nc2ccc(F)cc2)c(C)c1 +Cc1n[nH]cc1NC(=O)c1cccc(C(F)(F)F)c1 +COc1ncccc1CNC(=O)NC1CCN(CC(F)(F)F)C1 +CCOC(=O)c1ccccc1NC(=O)Cc1ccc(NC(C)=O)cc1 +CC(C)C(C)NC(=O)Cn1cnc2sccc2c1=O +c1ccc(CNc2cc(-c3ncnc4[nH]ccc34)c3cc[nH]c3n2)nc1 +COCC(=O)Nc1ccnn1Cc1ccccc1Cl +CC(=O)NCCNC(=O)CCCc1nc2ccccc2s1 +COC(=O)c1cccc(OC(=O)C2CCCO2)c1 +COCCCN(C)C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1noc(NC(=O)CCCNC(=O)c2ccc(F)cc2)n1 +Cc1ccc(C2CC(=O)Nc3c2cnn3C(C)C)cc1 +COc1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)cc1F +COCCOc1ccccc1NC(=O)Nc1ccc(C#N)cc1 +Cn1c(=O)ccn(CC(=O)NC2c3ccccc3CC2O)c1=O +O=C(CCc1ccccn1)NCCC(=O)N1CCCC1 +Cn1nc(NC(=O)Cn2cc(-c3ncccn3)cn2)c2ccccc21 +CC(C)(C)C(=O)Nc1cnc(-c2ccccc2)nc1 +Nc1cc(Cl)cc(Cl)c1S(=O)(=O)N1CCCCCC1 +Nc1ccc(NC(=O)Cn2ccccc2=O)c(Br)c1 +CCOc1cc(F)ccc1NCC(=O)Nc1cccc(C#N)c1 +CC(C)CCNC(=O)C1CCC(=O)N1CCc1ccccc1 +CCC(C#N)(CCN1CCOCC1)c1cccs1 +CC(C)c1nnc2sc(COc3ccccc3)nn12 +O=C(NCCc1ccccc1Cl)c1cccn1-c1cccnc1 +CCC(C)NC(=O)CNc1ccc(F)c(F)c1F +CCCNc1nnc(-c2sc(CC)nc2C2CC2)s1 +CN(CC1Cc2ccccc2CN1C)C(=O)CCc1cccnc1 +CC(=O)c1ccc(OC(=O)CSc2ccc(C#N)cc2)cc1 +COc1ccccc1CNC(=O)NCc1ccccn1 +COc1ccc(OCCN2C(=O)C(=O)c3cccc(Cl)c32)cc1 +COC(=O)C(NC(=O)c1cc(-c2ccc(OC)cc2)no1)C(C)C +O=C(Cn1cnnn1)N1CCCN(C(=O)c2cccc(Cl)c2)CC1 +O=C(Nc1ccccc1F)c1ccc(Cl)cc1-n1cnnn1 +O=C(Cn1cnc2ccccc2c1=O)Nc1cccc(Cl)c1 +CC(NC(=O)c1ccc(C#N)cc1)c1ccccc1 +Cc1cnc(C(=O)Nc2cccc(CN3CC(C)OC(C)C3)c2)cn1 +CCOc1c(Cl)cccc1NC(=O)c1scnc1C +CC(=O)Nc1ccc(F)c(NCc2ccc(F)cc2)c1 +CCc1ccc(NC(=O)CS(=O)c2n[nH]c(CC)n2)cc1 +COC(=O)CCCCNC(=O)Nc1cc(Cl)ccc1F +CCCCS(=O)(=O)N1CCCC(CNS(C)(=O)=O)C1 +Cc1csc(CNc2cc(C(=O)N(C)C)ccc2Cl)n1 +COc1ccc(CNC(=O)N2CCN(c3ncccn3)CC2)cc1O +CCN(CCO)C(=O)Nc1ccccc1C(=O)N(CC)CC +Cn1cc(S(=O)(=O)Oc2cc(Cl)cc(Cl)c2)cc1C(N)=O +COc1cc2ccccc2cc1C(=O)N1CCN(C(C)=O)CC1 +C#CCn1c(C(C)NC(=O)c2ccncc2)nc2ccccc21 +COC(=O)C(C)NS(=O)(=O)c1ccc(C)c(F)c1 +Cc1cc(C)nc(SCC(=O)Nc2nc3c(s2)CCCC3)n1 +O=C(NC1CCN(c2ccccc2Cl)C1=O)C1CCC1 +CCC(=O)N1CCCN(S(=O)(=O)CC2CCOCC2)CC1 +CS(=O)(=O)N1CCCC1C(=O)Nc1ccc(Cl)c(Cl)c1 +COCC(NC(=O)Nc1ccc2c(c1)CCC2=O)c1ccnn1C +CC(=O)c1c(C)oc(N)c1C(=O)c1ccc(F)c(F)c1 +Nc1cc(F)ccc1C1NCCc2ccc(Cl)cc21 +CCc1noc(CS(=O)(=O)c2ccc(C(F)(F)F)cn2)n1 +CC(=O)Nc1ccc(SCCCCCO)cc1 +Cc1cccc(CNC(=O)c2noc(-c3ccc4c(c3)OCO4)n2)c1 +Cc1ccc(CN(CC(O)c2ccccc2F)C(C)C)o1 +Cn1c(C(=O)Nc2ccc(C#N)cc2)cc2sccc21 +COC(=O)N1CCC(Nc2nc3ccccc3s2)CC1 +N#Cc1cccc(NC(=O)N2CCOC(c3ccccc3)C2)c1 +CCN(Cc1ccccc1NC(=O)c1ccncc1F)C(C)=O +Cc1noc(C(C)C)c1C(=O)NCc1ccccn1 +COCC(=O)N1CCC(Cn2c(C)nc3ccccc32)CC1 +Cc1nc(CC(=O)N2CCn3cccc3C2c2ccccc2)cs1 +CN(CC(=O)OCc1ncc(-c2ccc(F)cc2)o1)S(C)(=O)=O +CCCOc1ccc(F)cc1-c1cc(C(=O)OC)n(C)n1 +COc1cc(C#N)ccc1OCC(=O)Nc1ccc2c(c1)COC2 +O=C1CCC(C(=O)N2CCCCC2CCc2ccccc2)CN1 +CN1CCN(C(=O)c2nn(C)c3c2CN(Cc2cccs2)C3)CC1 +CC(=O)Nc1nc(CC(=O)NCCc2ccc(Cl)cc2)cs1 +CN(c1ccc(Cl)c(C(=O)N2CCCCCC2)c1)S(C)(=O)=O +Cc1ccc(Oc2ccc(NC(=O)N3CCCC(O)C3)cn2)cc1 +Cc1nc2ccc(C(=O)CN3CCCc4ccccc43)cc2[nH]1 +CC(=O)Nc1ccc(OCC(=O)N(C)Cc2cn(C)nc2C)nc1 +COCC(=O)Nc1ccc(Nc2nccc(C(F)(F)F)n2)cc1 +COC(C)c1cccc(NC(=O)c2cccnc2OCC(F)F)c1 +Cc1cc(=O)c2cccc(-c3ccc(S(C)(=O)=O)cc3)c2[nH]1 +CC(=O)N1CCN(CC(=O)NC(C)c2ccc(C)c(C)c2)CC1 +CC(=O)N1CCC(C(=O)Nc2ccccc2C(C)C)CC1 +O=C1COc2cc(C(=O)NCc3ccc(F)cc3)ccc2N1 +Cc1cc(C(=O)N(Cc2ccccc2)C(C)C)n[nH]1 +O=C(NCC1(N2CCOCC2)CCCCC1)c1csnn1 +COc1ncccc1CNC(=O)c1sccc1C +CC(C)CCNC(=O)c1ccccc1NS(C)(=O)=O +CN(Cc1cnn(C)c1)C(=O)COc1ccc(F)cc1Cl +CC(C)(C)NC(=O)CNC(=O)CNC(=O)c1ccsc1 +Cc1c(C(=O)NC2CCC(=O)NC2c2ccccc2)oc2ccccc12 +Cc1ccc2ncc(C(=O)Nc3nc(C)no3)n2c1 +CCCNC(=O)c1cnc(-c2ccccc2OC)nc1N +Cn1cc(C(=O)Nc2ccc3cc[nH]c3c2)c2ccccc21 +O=C(NCCc1c[nH]c2ccccc12)C(c1ccccc1)n1cnnn1 +O=C(Nc1ccnn1Cc1cccs1)c1ccc(=O)[nH]c1 +CN(CCOCC1CC1)S(=O)(=O)c1ccccc1C#N +CCCN(CCO)C(=O)Nc1cc(C(=O)OC)c(F)cc1F +Cc1cc(C(F)(F)F)nn1-c1ccc(NC(=O)c2ccn(C)n2)cc1 +Cc1cc(C)cc(NC(=O)c2cc3ccccn3n2)c1 +Cc1ccc(S(=O)(=O)CC(=O)NC2CCCCC2)cc1C +COC(C(=O)N(C)C1CCCCC1)c1ccccc1 +Nc1cccc(CCC(=O)Nc2cccc(Br)c2)c1 +CN1CCc2nc(C(=O)NCC(C)(C)C)sc2C1 +CN(C)C(=O)c1ccc(C(=O)Nc2cccc(C(F)(F)F)n2)cc1 +CCCc1cc(C(=O)NCCc2nc(C)cc(C(F)(F)F)n2)[nH]n1 +CCc1ccc(OC(C)(C)C(=O)N2CCNCC2)cc1 +CCOCC1CCN(C(=O)Nc2ccccc2SCC)C1 +O=C(CSc1nccc(=O)[nH]1)Nc1ccc(Cl)cc1Cl +CC(C)(C)c1nccc(N2CCN(C(=O)c3ccc(O)cc3)CC2)n1 +CC(C)(C)C(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +C=CCCCN(C)C(=O)c1cccc(NC(=O)CC)c1 +N#Cc1ncnc(C(F)(F)F)c1Cc1ccccc1 +CS(=O)(=O)N(CC(=O)NC1CCCC1)c1cccc(Cl)c1 +O=C(Nc1nnc(C2CCCC2)s1)C1CCC1 +CCC(C)c1ccccc1NC(=O)C(C)Sc1nncn1C +CC1CC1C(=O)Nc1ccc(C(=O)NCCCO)cc1 +CCCCN(C)S(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +Cc1ccccc1C1CCCN(C(=O)c2ccccc2-n2cncn2)C1 +c1cncc(-c2n[nH]c(SCC3CCCO3)n2)c1 +CCOc1cc(CO)cc2c1OC(CC)C(=O)N2C +COc1c(F)c(F)c(C(=O)Nc2ccc(F)cc2)c(F)c1F +O=C1CC(C(=O)Nc2ccc(Cl)c(Cl)c2)C2(CCCCC2)O1 +Cc1noc(-c2ccc(C(=O)NCCCNS(C)(=O)=O)cc2)n1 +O=C(Nc1ccccc1F)Nn1nnc2ccccc21 +COc1cc(C)c(C(=O)Cc2ccccc2)cc1OC +O=C(c1cccc(-c2ccccc2)c1)N1CCc2[nH]c(=O)sc2C1 +CCC(C)(C)NC(=O)C(C)Sc1ccc(N)cn1 +CN(C)S(=O)(=O)N(C)C(C#N)c1ccccc1 +CC(=O)N1CCN(C(=O)CCCOc2ccc(C(C)(C)C)cc2)CC1 +O=C(c1ccc2cccc(F)c2n1)N1CCOC2CCCCC21 +CCCn1nc(C(=O)N2CCC(c3nc(C)no3)CC2)ccc1=O +COCCOc1ccccc1NC(=O)N1CCCC1c1ccncc1 +Cc1ccc(NC(=O)N2CCC(S(N)(=O)=O)CC2)cc1 +C=C(C)CN(CC)S(=O)(=O)c1ccc(C)cc1 +Cc1cc(C(=O)NC(C)C)ccc1NCC(=O)N1CCNC(=O)C1 +Cc1ccc(C(C)NC(=O)Cn2cc(N)cn2)s1 +CNc1ncc(Br)c2c(N)cc(F)cc12 +COCCNC(=O)Cn1nc(-c2ccccc2)ccc1=O +Cc1ccc(NC(=O)N2CCC(NC(=O)c3ccc(C)o3)CC2)cc1 +Cc1ccc(C(C#N)CC(=O)NCc2ccncc2)c(C)c1 +Cc1csc(NC(=O)NCCCc2c(C)noc2C)n1 +CN(CC(N)=O)S(=O)(=O)c1ccc(OC(F)(F)F)cc1 +CNc1ncnc(Nc2ccc(Br)cc2F)c1N +CCOC(=O)c1csc(CNC(=O)c2sccc2CC)n1 +COC(C)(C)c1noc(C2CCCN(C(=O)c3ccncc3)C2)n1 +COC(=O)c1cc2n(n1)CCN(C(=O)Nc1c(C)noc1C)C2 +CCCC1CN(C(=O)c2ccc3c(c2)CCCC3)CCO1 +CC(c1ccccc1)N1CC(c2nc3ccccc3[nH]2)CC1=O +C=CCNC(=O)CNc1cccc(NC(=O)c2ccco2)c1 +O=C(Nc1ccc(-c2nccs2)cc1)c1n[nH]c(=O)c2ccccc12 +Cc1cnnn1-c1ccc(C(=O)NC(C)c2ccc(Cl)cc2)cc1 +CC(=O)c1cccc(NC(=O)COc2ccccc2C(N)=O)c1 +CC1CCc2c(sc3ncn(C(C)Cn4cncn4)c(=O)c23)C1 +O=C(Nc1cccc(F)c1)N1CCOCC1CC(O)c1ccccc1 +O=C(Nc1cccc(Cl)c1)c1ccc(N2CCC(O)CC2)nc1 +O=C(NCc1ccccc1)c1csc(-c2ccncc2)n1 +Brc1ccc(Nc2cccnc2)nc1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)C1CCCCC1 +CC1CN(C(=O)NCC(c2ccccc2)N2CCOCC2)CC(C)O1 +O=C(CCCn1cncn1)Nc1ccc2c(c1)OC1(CCCCC1)O2 +CC(=O)c1c(C)oc(N)c1C(=O)c1cscn1 +Cc1nn(Cc2ccccc2Cl)c(C)c1C(=O)N1CCN(C)CC1 +Cc1c(CN(CCCO)CC(F)(F)F)cc(C#N)n1C +COC(=O)c1ccc(S(=O)(=O)N=c2[nH]cccc2C)cc1 +Cc1ccccc1Cc1noc(CN2CCCC3(C2)OCCO3)n1 +O=C(NS(=O)(=O)Nc1cccnc1)c1c[nH]c2ccccc12 +Cc1nnc(COC(=O)c2c3c(nc4ccccc24)CCCCC3)o1 +O=C(Nc1ccc2c(c1)OCCCO2)c1ccc(-n2cccc2)cc1 +CC(OC(=O)CC1CCCC1)C(=O)Nc1ccc(Cl)cn1 +CC1(C)Nc2ccccc2N(CC(=O)NCc2ccco2)C1=O +Cn1nc(C2CCN(C(=O)Cn3cccc3)CC2)n(C2CC2)c1=O +CC(C)CN(CC(C)C)S(=O)(=O)c1c[nH]nc1N +Nc1cc(N)nc(SCc2nc(-c3ccccc3)no2)n1 +C#CCC(N)c1nc(C)c(C(=O)OCCC)s1 +CN(Cc1ccc2c(c1)OCCO2)c1ncnc2c1cnn2CCO +Cc1nn(C)c(C)c1CC(=O)Nc1cccc2ccccc12 +CC(C)(C)c1ccc(NC(=O)c2ccco2)c(N)c1 +Cc1cc(-n2c(C)cc(C(=O)OCc3cnn(C)c3)c2C)no1 +COC(=O)C1CC1C(=O)NC(c1nc(-c2cccnc2)no1)C(C)C +CNC(=O)Cc1ccc(NC(C)C(=O)Nc2ccccc2)cc1 +O=C(NCC1CCCO1)Nc1ccc(OCc2ccccn2)cc1 +COc1ccc(S(=O)(=O)NCc2cn(C)nc2C)cc1 +COCC(NC(=O)Cc1c(C)nn(-c2ccc(F)cc2)c1C)C(N)=O +O=c1n(CCO)c(=O)n(CCO)c(=O)n1CCO +OC(c1cc(F)cc(Br)c1)c1ccc2c(c1)COC2 +CSc1ccc(C(O)CNC(=O)NC(C)(C)C)cc1 +COC(=O)c1cc(-c2ccc(OC)c(OC)c2)n[nH]1 +O=C(NCc1cc(-c2ccccc2F)on1)c1ccco1 +CN(C)c1nc(-c2ccc3[nH]ccc3c2)ncc1F +Cc1cc(C)n(CC(O)COc2cccc(N)c2)n1 +CN(CCC#N)C(=O)c1cn(C)nc1-c1ccc(F)cc1F +CNC(=O)c1c(C)nc(N)nc1-c1ccc(C)cc1 +CCCC(NC(=O)Cc1nc2nc(C)cc(C)n2n1)c1ccccc1 +O=C(Cn1c(-c2cccnc2)noc1=O)NC1CCCCC1 +OCc1ccc(-c2nccn2CC2COc3ccccc3O2)o1 +CC(=O)c1cccc(NC(=O)CCn2ncc3cc(Cl)ccc32)c1 +COC(=O)NCC(=O)N1CCCCCC1c1ccncc1 +COc1ccc(NC(=O)Cn2ccccc2=O)c(OC)c1 +CN(C(=O)CCCCNC(N)=O)C1CCCCC1 +O=C(OCCc1cccs1)c1sccc1-n1cnnn1 +Cc1ccc(C(=O)Cn2nnc3ccccc32)cc1C +COCCCn1nnnc1SCC(=O)N1c2ccccc2CC1C +Cc1c(NC(=O)c2cc3ccccc3[nH]2)c(=O)n(-c2ccccc2)n1C +Cc1ccncc1NC(=O)NCC(C)(C)N1CCOCC1 +Cc1nc2cc(F)ccc2n1Cc1cccc(N)c1 +CCN(C)C(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +Cn1cc(C2CCCN2C(=O)c2ccc(N3CCOCC3)nc2)cn1 +O=C(CCOc1ccccc1)NCc1cccnc1 +CCC(=O)Nc1cc(-c2nc3ncccc3o2)ccc1C +Cn1cc(NC(=O)Cn2ccc(C(F)(F)F)n2)cn1 +COC(=O)c1ccc(OCC(O)Cn2ccnc2)cc1 +COC(=O)c1c(C(=O)OC)n(C)c2ccc(O)cc12 +O=C(NCCN1CCOCC1)c1ccc(Br)cc1 +O=C(OCCN1CCCC1=O)c1csc(Cc2ccccc2)n1 +Cc1nc2cccnc2n1C1CCN(C(=O)NC2CCCC2)CC1 +CC(=O)NCCNC(=O)CNC(C)c1ccc(Cl)cc1Cl +CN(CC(C)(C)O)S(=O)(=O)c1ccc(C#N)c(C(F)(F)F)c1 +CCOC1CCN(C(=O)NCc2cnn(C)c2)CC1 +Cc1cccc2c(=O)c3c(O)cc(OCC(N)=O)cc3oc12 +Cc1ccc(Cn2cnc3c(cnn3-c3ccc(C)cc3)c2=O)cc1 +COc1cccc(C(N)=O)c1OCC(=O)Nc1ccc(C)c(Cl)c1 +O=C(NCC1OCCc2cn(CC3CC3)nc21)C1CCOCC1 +CCc1onc(C)c1NC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +Cc1ccc(-c2nnc(CSc3n[nH]c(N)n3)o2)cc1 +CCS(=O)(=O)N1CCC(C(=O)NC(C)CO)CC1 +Cc1nn(C)c(C)c1C(=O)NCCOc1ccccc1-c1ccccc1 +c1ccc(-n2nnnc2CN2CCN(Cc3cccs3)CC2)cc1 +Fc1ccc2c(c1)-n1nc(C(F)(F)F)nc1CN2 +CC=CC1NCCc2cc(OCC)c(OC)c(Cl)c21 +CCCCS(=O)(=O)N1CCC(C(=O)NCc2ccccc2)CC1 +NC(C(=O)NC1CC1)c1ccc(Cl)c(Cl)c1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)c1ccc(N(C)C)cc1 +O=C(COc1ccc(F)cc1F)NCCCn1ncccc1=O +CCCN(CC1CC1)C(=O)Nc1cc(NC(C)=O)ccc1F +Cc1[nH]c2nc(CCc3ccccc3)nn2c(=O)c1C +CCN1CC(C(=O)NC2(CO)CCCC2)CC1=O +CC(C)(C)CC(=O)Nc1ccccc1CN1CCNC1=O +Cc1noc2ncn(CC(=O)N3CCc4ccccc4C3)c(=O)c12 +Cc1ccccc1C(C)NC(=O)CS(=O)(=O)c1nncn1C +Cc1nn(C(C)C)c(C)c1NC(=O)c1nn(C)c2ccccc2c1=O +C1CCC(Nc2nc3nonc3nc2NCC2CCOCC2)C1 +CC(C)(C)c1nc(CC(=O)Nc2ccc(-n3ccnc3)nc2)cs1 +Cc1ccc(C)c(OC(=O)CCc2nc(C(C)C)no2)c1 +N#Cc1ccc(CN2CCn3c(nnc3C(F)(F)F)C2)c(F)c1 +Cc1nc(C)c(C(=O)Nc2ccccc2-c2ccc(=O)n(C)n2)s1 +CC(C)NC(=O)c1cccc(CNC(=O)NCC2CCC2)c1 +CNC(=O)c1ccc(NC(=O)CCc2nc3ccccc3s2)cc1 +COc1cc(N)cc(CCC(=O)N2CCC(C)CC2)c1OC +C=CCn1c(C2CC2)nnc1S(=O)(=O)Cc1c(C)cc(C)cc1C +CCn1cc(Cl)c(CN(C)S(=O)(=O)c2cnn(C)c2)n1 +Cc1ccc2ncc(C(=O)NCCc3nc(C)c(C)s3)n2c1 +CN(CC(=O)NC(C)(C)C)C(=O)Cn1cc(Cl)cn1 +Cc1ccc(C(=O)NCCCOc2cccc3ccccc23)c(=O)[nH]1 +Fc1cccc(CNc2nnc3n2CCCCC3)c1 +NC(=O)NCCC(=O)N1CCC(c2nnc3ccccn23)CC1 +CCN(CC)C(=O)CCC(=O)Nc1cc(Br)ccc1C +COc1ccccc1NC(=O)NCCCn1ccc2cccnc21 +Cc1cccn2c(=O)cc(CS(=O)(=O)c3ccc(Cl)cc3)nc12 +O=C(c1cccnc1)N1CCc2onc(Cn3cccn3)c2C1 +CC(O)CC(C)CNC(=O)NCCc1cc(F)cc2c1OCOC2 +CC(C)C1COC2(CCCN(C(=O)c3cnn4cccnc34)C2)C1 +O=C(Cn1ccc2ccccc2c1=O)Nc1ccc(F)c(Cl)c1 +CC(=O)c1ccc(CNC(=O)C2CCOC2)nc1C +CCc1ncc(C(=O)NCC2(N3CCOCC3)CCCCCC2)cn1 +Cc1ccccc1C(=O)NC(C(=O)NCc1ccccc1F)C(C)C +O=C1Cc2cc(NC(=O)c3ccccc3O)ccc2N1 +Cn1cc(N2CCN(Cc3cc(C(N)=O)cs3)CC2=O)cn1 +CCCCNC(=O)c1cc(C)ccc1N1CCCC1=O +CC(NS(=O)(=O)c1cn(C)cn1)c1ccc(Br)cc1 +CC(=O)c1c(C)[nH]c(C(=O)Cn2nc(-c3cccs3)oc2=O)c1C +O=C(Nc1ccccn1)NC1CCN(c2ccccc2)CC1 +O=C(Nc1ccc2c(c1)OCO2)c1cnc2sccn2c1=O +COc1ccc(F)cc1CN(c1cccc(C#N)c1)S(C)(=O)=O +CCc1nc(CN2CCCCC2c2nc(-c3ncccn3)no2)no1 +COc1ccc(OCc2ccc(-c3nc(C#N)c(N(C)C)o3)o2)cc1 +O=C(NCc1cccs1)c1ccc(Cl)cc1 +O=c1ccc(C(F)(F)F)cn1Cc1ncnn1CCc1ccccc1 +Cn1ccnc1C(=O)Nc1ccccc1C(F)(F)F +C=CCOCC1c2nnn(C)c2CCN1Cc1ccc(OC)cc1 +CS(=O)(=O)c1cccc(OC(=O)C2CC3CCC2C3)c1 +CCSc1cc(C(=O)Nc2ccnn2Cc2ccc(C)o2)ccn1 +O=C(CCc1ccccc1O)NCc1ccccc1Cn1ccnc1 +Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc2c(c1)CC(=O)N2 +COc1ncccc1Cn1ccc(=O)c2sccc21 +O=c1[nH]c2c(s1)C1(CCCC1)c1sc(=O)[nH]c1S2 +COC(=O)CCc1csc(Cc2cc(C)ccc2OC)n1 +CC(O)(CNC(=O)c1coc(-c2ccccc2)n1)c1ccsc1 +O=C(CNc1cc(F)ccc1F)NCc1ccc2c(c1)OCO2 +CCNC(=O)c1ccc2c(c1)nc1n2CCN(CC2CCCO2)C1 +CCOCC(O)CN1CCN(C(=O)c2ccnc(C)n2)CC1 +COc1cccc(-c2cc(NC(=O)c3csnn3)n(C)n2)c1 +Cc1cc(CN(C)C(=O)Nc2ccc(OC(C)C)cc2)no1 +COc1cc(C(=O)Nc2ccc(SC)cc2)ccc1OC(F)F +CCC1CCC(NC(=O)c2c(C)noc2C)CC1 +O=C(NCC(=O)N1CCc2ccccc2C1)c1ccc2cc[nH]c2n1 +O=C(Nc1cccc2cccnc12)c1cccs1 +Cc1ccccc1-n1ncc(C(=O)N(CC(N)=O)C(C)C)c1C +Cc1ccc(-c2nc(CCNC(=O)CCn3cncn3)cs2)cc1 +CC#Cc1nnc(C(N)c2ccc(C#N)cc2OC)o1 +Cc1n[nH]c(-c2ccc(NC(=O)c3scnc3C3CC3)cc2)n1 +NC(=O)Nc1cc(Br)cc(Cl)c1F +CC(OCC1CC1)C(=O)Nc1nc2ccc(F)cn2n1 +Cn1cnc(CNC(=O)c2ccc(OCc3ccccc3)cc2)n1 +COc1cc(C(=O)N2CCOc3ccccc32)ccc1OCC(N)=O +Cc1ccc2c(c1)NC1(CCCC1)C(=O)N2CCCO +Cc1noc(C)c1CNC(=O)c1c[nH]nc1-c1ccccc1 +O=C(COc1ccc(F)c(Cl)c1)Nc1ccon1 +Cc1ccc(C(C#N)NCc2ccc(F)cc2)cc1 +Cn1cc(-c2cccc(-c3ccn(CC(O)c4ccccc4)n3)c2)cn1 +COc1ccc(C(=O)Nc2c(C)nc3sccn3c2=O)cc1OC +COC(C)(C)c1noc(C2CCCN(Cc3cccc(F)c3)C2)n1 +O=C(c1ccc(F)nc1)N1CCCc2cc(F)ccc21 +Cn1c(CNC(=O)c2sccc2C#N)nc2ccccc21 +NS(=O)(=O)N1CCc2ccccc2C1Cc1ccccc1 +COC(=O)Nc1ccc(NC(=O)N(C)Cc2ccccn2)cc1 +Cc1ccc(C(=O)NCc2c(C)noc2C)c(=O)[nH]1 +CC(C)Cc1nc2cc(N)cc(Br)c2n1C +CC(=O)c1ccc(S(=O)(=O)Nc2ccccc2C#N)cc1 +CN(CC(=O)NCCc1nc2c(s1)CCCC2)S(C)(=O)=O +CCN(Cc1ccc2c(c1)OCO2)C(=O)CC(C)C +COc1ccc(NC(=O)NCCN(C)c2ccccc2)cc1F +O=C(NCCc1cc(F)ccc1F)c1cnc(C2CCCO2)s1 +Cc1nc(-c2cccc(CNC(=O)c3ccnc4ccccc34)c2)n[nH]1 +CC(C)Nc1nc(-c2ccc3c(c2)OCCCO3)ccc1C#N +N#Cc1cccc(NC(=O)c2cccc(F)c2F)c1 +Cn1cnc2cc(OC(=O)c3cc(-c4ccco4)n[nH]3)ccc21 +CCC(C)NC(=O)Cc1cc(OC)ccc1OC +Nc1cc2c(cc1F)N1CCCC1=NS2(=O)=O +O=C(c1c(O)cc(F)cc1F)N1CCC(O)(C(F)(F)F)CC1 +CC(C)C(=O)N1CCC(n2nc(-c3cccs3)ccc2=O)CC1 +Cc1noc(C)c1CCC(=O)N1CCCSc2ccccc21 +NC(=O)Cc1ccc(NS(=O)(=O)c2ccc(F)c(Cl)c2)cc1 +Cc1ccc(NC(=O)CSc2nnc(C)n2C)cc1Cl +Cc1ccncc1NC(=O)NCc1cnn(Cc2ccccc2)c1 +Cc1ccc(OCC(=O)Nc2ccc(CC(=O)N(C)C)cc2)c(C)c1 +Cn1c(CNC(=O)c2c(F)cccc2F)cc(=O)n(C)c1=O +O=C(Nc1nccs1)C1CCN(C(=O)c2ccccc2F)CC1 +CC(c1ccccc1F)N1CCN(c2ccccn2)CC1 +O=C(CCc1nc(-c2ccsc2)no1)N1CCN(CCO)CC1 +CCn1nc(C)c(NC(=O)c2cccc(-c3nnnn3C)c2)c1C +O=C(c1ccc(O)cc1)C1CCN(C(=O)C2CC2c2ccccc2)CC1 +COC(=O)c1ccc(OC(C)C)c(NC(=O)c2ccc(C)nc2C)c1 +Cc1ccc(S(=O)(=O)N2CCN(C)C(C)C2C)c(F)c1 +COc1ccc(S(=O)(=O)n2cc(-c3ccc(C)cc3)c(N)n2)cc1 +O=C(COc1ccc(F)cc1Cl)N1CCN(C(=O)C2CC2)CC1 +CCN(C(=O)c1ccco1)C(C)c1ccc(F)cc1 +O=C(c1cccnc1)N1CCCC(c2cc(=O)nc3n2CCC3)C1 +O=C(COc1ccc(-c2nnco2)cc1)Nc1ccc(F)c(Cl)c1 +CCC(C)C(C)Nc1cccc(S(C)(=O)=O)c1 +CCSc1nc2n(n1)CC(C(=O)Nc1ccccc1OC)=C(C)N2 +CC1CCCN(C(=O)CNc2ccccc2C(N)=O)C1 +Cc1cc(NC(=O)c2ccc(Cl)c3cccnc23)n(C)n1 +COCCCNc1nc2sc3c(c2c(=O)n1C)CCCC3 +Cc1occc1COC(=O)Cn1c(=O)[nH]c2ccccc21 +Cc1ccccc1C(=O)Nc1nn(C)c2ncccc12 +CC(NC(=O)c1ccc(=O)[nH]c1)c1ccc(F)c(Cl)c1 +COC(=O)c1cnc2nc(C)ccc2c1Nc1ccc(F)cc1 +O=C(NCCc1cccs1)NCc1ccccc1OC(F)F +Cc1nn(C)c2nc(N(CCO)CCO)sc12 +C=C(C)C1CC=C(CN2CCN(C(=O)OCC)CC2)CC1 +Cc1ccc(C(C)NC(=O)CNC(=O)c2cc(F)cc(F)c2)o1 +N#Cc1ncn(-c2ncnc3scc(-c4ccc(Cl)cc4)c23)n1 +CN(C)C(=O)c1cccc(-c2ccc(O)c(C#N)c2)c1 +COc1ccc(CN(C)C(=O)CNc2ccc(Cl)cc2F)cc1 +O=C(Cn1c(=O)[nH]c2ccccc21)Nc1ccc(F)cc1F +CC(=O)c1ccc(NCc2cccc(C#N)c2)cc1 +Cc1c(Cl)cccc1-c1ccc(CNn2cnnc2)o1 +O=C(Cn1c2ccccc2c(=O)c2ccccc21)OCCn1cncn1 +Cc1nc(CN2C(=O)CSc3ccccc32)n(C)n1 +O=C(NCC(F)(F)F)c1cn(-c2ccccc2)nn1 +O=C(Nc1ncccn1)c1cc(Br)ccc1Cl +CC(O)c1ccccc1NC(=O)CCc1ccsc1 +C=CCN(CC=C)C(=O)c1c[nH]c2ccc(N)cc12 +COc1cc(OC)c(NC(=O)N(Cc2ccncc2)C2CC2)cc1F +CC(C)Cc1nc(C(=O)Nc2ccccn2)cs1 +O=C(CNC(=O)c1ccsc1)Nc1nc(C2CC2)cs1 +Cc1ccc2ncc(C(=O)Nc3ccnc4ccnn34)n2c1 +CCCN(CCC)c1cnn(-c2ccccc2)c(=O)c1N +CC(C)(O)c1nnn(Cc2ccccc2)c1C(C)(C)O +COc1cc(OC)cc(C(=O)N(C)Cc2ccc(C)o2)c1 +COCCN1CC(C(O)c2ccc(F)cc2)CC1=O +Cc1n[nH]c(C(=O)NCC2CC2)c1Br +CC(=O)c1[nH]c(C)c(C(=O)N2CCC3(CN(C)C(=O)O3)C2)c1C +O=S(=O)(c1cn[nH]c1)N1CCC(Cc2cccc3ncccc23)C1 +CC(CNC(=O)Cc1c(F)cccc1F)c1ccsc1 +CCN(CC(F)(F)F)C(=O)c1cc(Br)cn1CC +O=C1CCN(C(=O)Cc2c[nH]c3ccccc23)CCN1 +CC(=O)Nc1ccc(C)cc1NCC(=O)Nc1ccc(C)cc1 +Cc1cc(CNC(=O)c2ccccc2Oc2cccnc2)c(C)o1 +COc1cc(C(=O)Nc2ccccc2-n2cnnn2)ccc1C +CCNC(=O)NC1CCC(OC(=O)CC(C)(C)C)CC1 +Cc1nnc(SCC(=O)NC(CC(C)C)c2ncnn2C)s1 +CCOc1ccccc1CCC(O)c1ccccn1 +CCOC(=O)C(Nc1cccc(C(=O)NC)c1)c1ccccc1 +CCCC(=O)N1CCCC(C(=O)NCc2cscn2)C1 +COc1cccn(Cc2ccc(C(N)=O)cc2)c1=O +Cc1n[nH]c(N2CCN(c3ccccc3F)CC2)nc1=O +COc1ccc(-c2nn(-c3ccccc3)cc2C2=NCC(=O)O2)cc1 +Cn1ccnc1SCC(=O)c1ccc(NS(C)(=O)=O)cc1 +N#Cc1cccnc1Sc1nnc(NC2CC2)s1 +CC1CN(S(=O)(=O)CCCc2ccccc2)CCO1 +Cn1cc(CNC(=O)c2cccc(NC(N)=O)c2)cn1 +COc1ccc(C)cc1NC(=O)c1cc(Cl)ccc1N +CC(NC(=O)C1CCCCC1)C(=O)N(C)c1ccc(F)c(F)c1 +Cc1nn(C)c(C)c1OCCOc1ccccc1C#N +CC1Oc2ccccc2N(CC(=O)N(C)CCC(F)(F)F)C1=O +Cc1ccc(CN(C(=O)CSc2nc(C)c(C)o2)C2CC2)cc1 +CCCN(Cc1cc(C#N)ccc1F)CC(F)(F)F +O=C(c1cccs1)c1c2[nH]c(=O)[nH]c(=O)c2c2ccccn12 +C#CCOc1ccc(CNCC(O)c2ccccc2)cc1 +O=C(CN1CCN(c2ccc(Cl)cc2)C1=O)NCC(F)(F)F +CCn1nc(C)c(CNC(=O)Nc2ccccc2Cl)c1C +Cc1cc(C)cc(OCCNC(=O)c2nccnc2N)c1 +Cc1nc(COc2cccc3cccnc23)cs1 +CC(C)(C)c1csc(CCNCc2ccncc2)n1 +Cn1c(CNC(=O)Nc2ccccc2Cl)nnc1C1CCC1 +Cc1cc(Br)c2oc(C(=O)NCc3ncoc3C)cc2c1 +Cc1csc(N(C)C(=O)c2cccnc2N2CCCCC2)n1 +Cc1n[nH]c2c(Nc3cccc(Cn4ccnc4)c3)ncnc12 +COCCN(C)C(=O)NCc1noc(-c2ccsc2)n1 +Cc1ccc(NC(=O)c2n[nH]c3c2CCC3)c(OCC(=O)N(C)C)c1 +COc1ccnc(N2CCC(C(=O)NCCNC(C)=O)CC2)n1 +CCCCC1C=CCN1C(=O)Nc1cnn(CC)c1 +Cc1cccc(OCCN2C(=O)C3(OCCCO3)c3ccccc32)c1 +Cn1nnnc1SCCC(=O)Oc1ccc(Br)cc1 +COC(=O)c1cc(-c2cc(OC(C)C)ccc2O)n[nH]1 +CC(=O)Nc1nnc(SCc2ccccc2C#N)s1 +Cc1c(N)cccc1NC(=O)COc1ccccc1F +CC(C)n1nccc1C(=O)OCC1CN(Cc2ccccc2)CCO1 +CCc1nc(CN2CCN(C(=O)c3cccc(OC)c3)CC2)cs1 +O=C(Nc1cnn(Cc2ccccc2F)c1)c1nc2ncccn2n1 +CCOCCOCC(=O)Nc1cccc(Cl)c1C +CC(C)(C)OC(=O)N1CCCC1C(=O)NCc1cccc(F)c1 +CCC1CCCCN1C(=O)CS(=O)(=O)c1nnc(N(C)C)s1 +COC1CCN(C(=O)c2ccc(C#N)cc2)C1Cc1cnn(C)c1 +COCc1cccc(CNC(=O)Nc2cccc(Cl)c2OC)c1 +CCCOc1ccccc1NC(=O)c1ccc2c(c1)CCN2C(C)=O +O=C1CC(c2ccco2)Cc2nc3c(-c4ccccc4)cnn3cc21 +Nc1c(N2CCCCCC2)ncnc1-n1nnc2ccccc21 +CCCC(=O)NCC(=O)Nc1ccnn1CC(C)C +Cc1ccc2nc(C)c(C(=O)NC(C)c3ccncc3)cc2c1 +CC(C)(C)c1ccc(OCCN2CCCC2=O)cc1 +Cc1nn(-c2ccc(F)cc2)c2c1c(=O)c(C(=O)NC1CC1)cn2C +CCOC(C)c1noc(CNc2cc(C)ccc2C)n1 +CN(CCC#N)S(=O)(=O)c1ccc(Br)cc1Cl +Nc1cccc(-c2csc(NC(=O)c3ccc(F)c(F)c3)n2)c1 +CCCC(=O)NCC(=O)N1CCC(Oc2cccc(Cl)c2)C1 +CS(=O)(=O)N(CC(=O)N1CCc2ccccc21)c1ccccc1F +Cc1nnc(SC(C)c2nc(C3CC3)no2)n1N +CC1CCc2c(cnc3c(C(=O)NC(C)c4ccccc4)cnn23)C1 +CC(C)COc1cccc(C(=O)N(C)C(C)C(O)c2ccccc2)c1 +Cc1n[nH]cc1CNC(=O)c1cccc(N(C)C)c1 +Cc1cc(C)c2c(c1N)C1(CCOCC1)S(=O)(=O)N2C +CC(C)n1c(C(=O)NCc2ccncc2)cc2sccc21 +Cc1ccc(S(=O)(=O)CCC(=O)Nc2nccs2)cc1 +NS(=O)(=O)c1ccsc1C(=O)OCc1cccc2ccccc12 +CC(C)OC(=O)CCc1nc(-c2ccco2)no1 +N#CCSc1nnc(-c2ccc3nc[nH]c3c2)o1 +COC(=O)CCCc1csc(NC(=O)c2cc[nH]c2C)n1 +O=C(COCC1CCCO1)N1Cc2cnc(-c3ccccc3)nc2C1 +COCCN1CCN(C(=O)c2ccc(COC)o2)CC1=O +Cc1csc(NC(=O)C2(c3cc(-c4ccccc4)on3)CC2)n1 +Nc1ccc(C2NCCc3cccc(OC(F)F)c32)cc1 +Cc1onc(N)c1S(=O)(=O)N1CCN(CCO)CC1 +COc1ccc(-n2ccc(CNC(=O)OCC(F)(F)F)n2)cc1 +COC(=O)CCN(C)C(=O)c1cc(SC)ccc1Cl +O=c1c2ccc(Br)cc2ccn1CCCO +O=C(CCCc1cc(F)ccc1F)NCC(F)(F)F +COc1ccc(C(NC(=O)C2CNC(=O)N2)c2ccc(F)cc2)cc1 +COc1cccc(C(=O)N2CC3CCC2C3Oc2ccccn2)c1 +O=C(Nc1ccc(OC(F)F)cc1)c1nc2ncccn2n1 +CCOC(=O)c1ncn2c(=O)n(C3CCCCC3)nnc12 +CCCn1nnc(NC(=O)c2ccc(OCC)c(Cl)c2)n1 +CCN1CC(C(=O)N2CCN(c3ccccc3)CC2)CC1=O +O=C(Cc1ccc(Cl)c(Cl)c1)Nc1nccs1 +Cc1cccc(NC(=O)Cn2c(=O)cnc3ccccc32)c1 +COC(=O)C(C)(C)NC(=O)c1ccc(SC)cc1 +Cc1nnc(N2CCCC3(CN(C(=O)c4c[nH]cn4)CCO3)C2)o1 +Cc1ccc(N(CCC#N)C(=O)COc2cccc(C#N)c2)cc1C +Cc1ncc(C(C)NCc2cccnc2OC2CCCC2)s1 +CCc1sc(-c2cnccn2)nc1-c1ccccc1 +O=C(Nc1ccccc1O)C1CCCN1c1ncnc2sccc12 +CC(NC(=O)c1ccc(C(=O)N(C)C)cc1)c1ccccc1 +CC(C)NC(=O)Cc1ccc(NC(=O)c2cnc3[nH]ccc3c2)cc1 +COC(=O)C1CCCn2nc(-c3ccccn3)nc21 +CSc1ccc(NC(=O)CCc2nc(C)no2)cc1 +CCOc1cc(F)ccc1NC(=O)C(OC)c1ccccc1 +Cc1c(C(N)=O)sc2nc(-c3ccccc3)cn12 +Nc1n[nH]c2nc3cc(Br)ccc3cc12 +O=C(CCc1ccc2c(c1)OCO2)NCCn1cnc2ccccc21 +Cc1cc(C)c(C(=O)NCCCn2cccn2)c(C)c1 +Cn1c(=O)c2c(SCC#N)ccnc2n(C)c1=O +CC(=O)Nc1cccc(OC(=O)c2snnc2C)c1 +CC(=O)N1CCCC1C1NCCc2cc(F)c(Cl)cc21 +Cc1ccccc1C1CCCN1C(=O)C1CC=CC1 +CC1=NC(=O)C(CCC(=O)NC(C)c2ccccc2C)C(C)=N1 +CCc1nc2ccccc2c(=O)n1CC(=O)Nc1ccc(C(C)=O)cc1 +COCCn1cnnc1SCC(=O)c1ccc(F)cc1F +CNC(=O)Nc1ccc(C2(C(=O)NCC3CCCO3)CCC2)cc1 +Cc1ccccc1CCNC(=O)NCc1nnc2n1CCCCC2 +CC(C)c1noc(CCNC(=O)Nc2ccc3[nH]ccc3c2)n1 +O=C(Nc1cc(C(F)(F)F)ccc1O)c1cccs1 +CCn1cc(NS(=O)(=O)c2cnc3c(c2)c(C)nn3C)cn1 +CCN(CC)S(=O)(=O)N(Cc1ccc(C)c(C)c1)C1CC1 +COCc1ccc(S(=O)(=O)Nc2ccc(C)cc2F)cc1 +COC(=O)C(C)NC(=O)c1ccc(F)cc1NC(=O)C1CC=CCC1 +COc1ccc(N(C)C(=O)c2cccnc2OCC(F)F)cn1 +Fc1cc(CCNc2ncnc3[nH]cnc23)c2c(c1)COCO2 +COCc1nn2c3c(nnc2c1-c1ccccc1)C(=O)CC(C)C3 +NC(=O)CC1CCN(C(=O)C2CCCN(C(N)=O)C2)CC1 +CCn1c(N2CCC(C(=O)N3CCCCC3)CC2)cc(=O)n(C)c1=O +O=C(NCCCOc1ccc(F)cc1)NC1CC1 +Cn1ncc(Br)c1C(=O)Nc1ccc(C(F)(F)F)cc1 +C#Cc1cccc(NC(C)c2ccc(OC)c(OC)c2)c1 +CCCC(=O)N(C)C(C#N)c1ccc(Br)cc1 +CCc1onc(C)c1NC(=O)C(CC)c1ccccc1 +Cc1cc(C)n(Cc2cc(C(=O)NCCc3cscn3)n[nH]2)n1 +CC(=O)N(C)CC(=O)Nc1cccc(C(=O)Nc2cccc(F)c2)c1 +COc1cc(N)ccc1S(=O)(=O)Nc1ccccn1 +Cn1cccc1C1CCCCCN1C(=O)Cc1cn2ccsc2n1 +CCn1nc(C)c(CN(C)S(=O)(=O)c2ccc(C)c(C)c2)c1C +O=C(Nc1cccc2[nH]cnc12)c1cccc(-n2cccn2)n1 +CCn1c(=O)c2ccccc2n2c(SCC(N)=O)nnc12 +NS(=O)(=O)NCC1CCN(c2ccccc2)C1 +CCN(CC)C(=O)c1ccccc1N(C)S(C)(=O)=O +CC(NC(=O)c1cc(C(N)=O)cs1)C1CCCO1 +Cc1nc(-c2ccccn2)sc1C(=O)NC(C)c1ccncc1 +CC(Cc1ccco1)NC(=O)NC1CCCCNC1=O +Nc1ccc2c(c1)N(CCCO)C(=O)CS2(=O)=O +CCc1n[nH]c(SC(C(=O)N2CCCCC2C)C(C)C)n1 +O=C(Cc1ccc(F)cc1F)NCC(=O)Nc1ccccn1 +CCCCN(Cc1cc2cccc(C)c2[nH]c1=O)C(=O)c1ccccc1 +CCc1noc(C)c1C(=O)N1CCN(Cc2ccc(F)cc2)CC1 +COc1ccc(F)c(-c2cccc(CNC(C)=O)c2)c1 +CCc1ccc(CN(C(=O)CNC(=O)c2cccs2)C2CC2)cc1 +Cn1c(CS(=O)(=O)c2ccc(Cl)c(Cl)c2)nnc1C1CC1 +Cc1cc(C)n2nc(CC(=O)OCCNc3ncccn3)nc2n1 +Cc1noc(C(=O)Nc2cc(Br)ccc2O)c1Cl +O=C(COCC(F)(F)F)N(Cc1cccnc1)c1ccc(F)cc1 +CCN(CC)C(=O)C(C)N1CCN(CC(F)F)CC1 +COCC(C)N1CCN(C(=O)CCc2ccc(Cl)cc2)CC1 +Cc1cc2c(NCCC(=O)NCc3ccco3)ncnc2s1 +O=C(CC1CSc2nccc(=O)n21)NCCC1=CCCCC1 +O=C(Cc1cccnc1)NC1c2ccccc2Oc2ccccc21 +CCCN(C)C(=O)c1nc(C(C)C)ncc1Cl +NCC(=O)c1c[nH]c2c(Br)cccc12 +CC(=O)N(C)C1CCN(C(=O)c2cncnc2C)C1 +CCC(CC)NC(=O)NC1CCOc2c(Cl)cccc21 +COc1cccc(NC(=O)c2ccc(-n3ccnn3)cc2)c1 +c1cnc(N2CCCC(c3cccc(-n4ccnc4)n3)C2)nc1 +N#CC1CN(Cc2cc(O)ccc2Br)CCO1 +COc1cccc(C(=O)N(CC(N)=O)Cc2ccccc2)c1OC +Cc1nn(C)c(C)c1CNC(=O)c1csc(NC2CC2)n1 +CCOC(=O)NCCc1nc(-c2ccncc2)no1 +COc1ccc(OC)c(-c2nc3ccccn3c2N)c1 +O=C(c1noc2c1CCCC2)N1CCN(Cc2ccsc2)CC1 +Nc1nncn1C(=O)c1cc(Cl)ccc1OCc1ccccc1 +COc1cc(N)c(NC(=O)c2ccc(-n3cccc3)cc2)cc1OC +COc1ccc(C(=O)NCC2CCCCC2=O)cc1 +Cc1cccc(NC(=O)Cn2cc(C(F)(F)F)cc(Cl)c2=O)c1 +O=C(CCCc1nc(-c2ccccc2)no1)NC1CCCOC1 +COC(=O)C(NC(=O)Nc1ccc(F)cc1)C(C)C +O=C(NCCN1CCCCCC1=O)NCc1nnc2ccccn12 +Cc1nccc(CNC(=O)c2cccc(NC(=O)OC(C)(C)C)c2)n1 +COCc1noc(C(C)Sc2nc3ncc(Cl)cc3[nH]2)n1 +CC(C)C(C)NC(=O)CS(=O)(=O)c1ccccc1Cl +Cn1nc(-c2ccc3ccccc3c2)cc(CC#N)c1=O +O=C(Cn1nc2n(c1=O)CCCCC2)Oc1ccc(Cl)cc1 +O=C(Cc1cccc(F)c1)NCc1cccnc1OCC(F)(F)F +CCC1(CNC(=O)Cc2cccc(OCC#N)c2)CC1 +O=C(Nc1ccccc1F)c1ccc2[nH]ccc2c1 +COc1ccc(NC(=O)Nc2ccc(F)cc2)cc1 +CC(C)c1nnc2n1CCN(C(=O)c1cc(-c3ccco3)on1)C2 +COc1cc(C)ccc1OCCC(=O)NCc1cccc(C)c1 +CNC(=O)CC(c1cc(OC)ccc1OC)C(C)C +O=C(c1cscn1)N1CCC(c2noc(-c3ccccn3)n2)CC1 +CC1(C)Oc2[nH]c(=O)[nH]c(=O)c2C2c3ccccc3OCC21 +Nc1nonc1-c1nc2ccccc2n1Cc1ccc2c(c1)OCO2 +Cc1cc(C(=O)N2CCC3(CCCO3)CC2)c2cnn(C(C)C)c2n1 +CC(C)Cc1nn2c(CO)c(-c3ccc(F)c(F)c3)nc2s1 +O=C(Nc1ccc(OC2CCC2)c(F)c1)N1CCC(O)C1 +Nc1ccccc1CCC(=O)NCc1ccc(Cl)cc1 +N#Cc1ccc(NC(=O)c2cnc(Cc3ccccc3)s2)cc1 +C=CCOc1cc(Br)c(CO)cc1OC +COCC(=O)N1CCN(C(=O)c2cnns2)CC1 +CNS(=O)(=O)c1csc(C(=O)Nc2cc(F)ccc2OC)c1 +CC(C)C(=O)Nc1ccc(-c2nn3cnnc3s2)cc1 +CSc1cc(-c2ccc(Br)cc2)oc(=O)c1C#N +Cc1nn(C)c(C)c1C(C)NC(=O)Nc1ccccc1 +COCCn1c(SC(C)C(=O)N(C)C)nc2cc(Cl)ccc21 +COC(=O)c1ccc(COc2ccc(-c3csc(C)n3)cc2)o1 +O=C(CNC(=O)c1ccncc1)NCC1CCCC1 +COC(=O)C1CCCN(C(=O)c2ccc(C)c(C)c2)C1 +CCc1nnc(SCCC(=O)NCc2ccc3c(c2)OCO3)n1N +Cc1ccc(CCNC(=O)C2(C)Oc3ccccc3NC2=O)o1 +CC(C)C1CN(C(=O)C2(C)CC2)CCC(=O)N1Cc1ccc(F)cc1 +CC(NC(=O)NC1CCCCC1)C(=O)N1CCCCC1C +COC(=O)c1cnc2c(C)c(-c3ccc(Cl)cc3)nn2c1N +Cc1ccc(-n2c(C)nnc2SCC(=O)NC(C)(C)C)cc1 +COc1ccccc1N1CCN(CC(=O)NCC(F)(F)F)CC1 +Cc1nc(S(=O)(=O)NCC2(c3ccc(F)cc3F)CC2)cn1C +COc1cccc(C2CCCN2C(=O)Nc2cnn(C)c2)c1 +CCc1ncc(CN(CCO)Cc2cccs2)cn1 +NC1=NC(=O)C(Cc2ccccc2)(c2ccc(Cl)c(Cl)c2)N1 +O=C(CSc1nccc(=O)[nH]1)c1cccs1 +COCCOCC(=O)Nc1nnc(C(F)(F)F)s1 +COC(=O)COc1cccc(NC(=O)Cc2cccc(F)c2)c1 +CCNc1cccc(C(=O)Nc2ccc(OC)nc2)c1 +CCOc1ccc2ccccc2c1CNn1nnnc1N +CC1CN(C(=O)c2csc(-c3cc4ccccc4[nH]3)n2)CC(C)O1 +CCOc1ccc(C(=O)NCCO)cc1OCC +Cc1cc(C)c(CNC(=O)NC2CCCCNC2=O)c(=O)[nH]1 +Cc1noc(C)c1CCCNS(=O)(=O)c1cccc2ccccc12 +C=CCn1ccc2ccn(CC(=O)N3CCOCC3)c(=O)c21 +O=C(Nc1cccc(OC(F)F)c1)c1cnn(-c2ccccc2)n1 +Cc1ccc(CC(=O)NC2(c3ccc(Br)cc3)CC2)cn1 +O=C(c1cc[nH]n1)N1CCc2c(nc(N3CCCC3)[nH]c2=O)C1 +CCNc1nc2c(c(=O)n(C)c(=O)n2C(C)C)n1CC +CC(NC(=O)c1cn(Cc2c(F)cccc2F)nn1)c1ccncc1 +Cc1cc(C(=O)OCCNc2cccnn2)c(C)s1 +CC1(C)CNC(=O)c2nc(C3CCCN(S(C)(=O)=O)C3)[nH]c2C1 +CCC(C)C(NC(=O)CCn1cnc2sccc2c1=O)C(N)=O +COC(=O)c1[nH]c(C)c(C(=O)COc2ccccc2F)c1C +c1ccc2oc(CN3CCCC3c3noc(C4CC4)n3)nc2c1 +O=C(Nc1n[nH]c(-c2ccco2)n1)c1c[nH]c2ccccc2c1=O +Cc1cccc(NCc2cc(=O)n3c(C)csc3n2)c1 +Cc1cc(NCC(=O)NC(C)(C)C)n2ncnc2n1 +COc1ccc(C(=O)N2CC(C)OC(C)C2)cc1F +COc1ccc(NC(=O)Nc2cc(F)ccc2F)cc1OC +Cc1nc(-c2ccc(NC(=O)NCc3ccco3)cc2)no1 +COCCN(Cc1ccc(F)cc1Cl)C(=O)C1CC2CCC1O2 +O=C(NCc1cc[nH]n1)C1(c2ccc(Cl)cc2)CCCC1 +CCN(CC1COc2ccccc2O1)S(=O)(=O)c1ccc(C)cc1 +Cc1cc(C)c(C(=O)NC2CCc3ccccc3C2)c(=O)[nH]1 +CC(C)c1ccc(S(=O)(=O)NCC(C)(O)C2CC2)cc1 +CC(C)Cc1nnc(NS(=O)(=O)c2cccc(N)c2)s1 +CN(CCCNC(=O)C1Cc2cc(F)ccc2O1)c1ccccc1 +CC(COc1ccc(F)cc1F)NC(=O)c1ccoc1 +CNC(=O)c1ccc(NC(=O)N2CCCC3CCCC32)cc1 +CSc1ncccc1C(=O)OCC(=O)C1=NC=CC1 +Cn1cnc(-c2ccc(F)cc2)c1NC(=O)Cc1ccc[nH]1 +CCOc1ncccc1CNC(=O)c1c(C)noc1C +Cc1cc(C)n(CCC(=O)Nc2cccc(Br)c2)n1 +CCc1n[nH]c(SC(C)C(=O)Nc2cc(Cl)cc(Cl)c2)n1 +Cc1cc(Oc2ccc(-c3noc(C)n3)cc2)nc(C)n1 +COc1ccccc1-c1cc(C#N)nn1CC(C)C +Cc1nnc(-c2ccc(NC(=O)c3ccc(-n4ccnn4)cc3)cc2)o1 +O=C(COC(=O)c1cc(Cl)c2c(c1)OCO2)NCC(F)(F)F +O=C(Cc1ccon1)Nc1ccccc1N1CCc2ccccc21 +COc1ccccc1CCNS(=O)(=O)c1cccc(O)c1 +CNS(=O)(=O)c1cc(NC(=O)c2ccc(OC)cc2)ccc1C +Cn1cnnc1SCc1nc2ccccc2n1C(F)F +CC1CCCCC1OCCNC(=O)Nc1cc(C(N)=O)ccc1F +COC(=O)CC(C)(C)CC(=O)Nc1cccc(-c2ncn(C)n2)c1 +CCc1cc(=O)[nH]c2nnc(SCC(=O)N3CCC(C)CC3)n12 +CCC1CN(Cc2cnc(-c3ccc(C)o3)s2)CC(C)O1 +O=C1OC2CC3CC2C1C3C(=O)N1CCc2ccccc21 +CC(C)(C)CC(=O)N1CCC(c2cnn(-c3ccc(F)cc3)c2)CC1 +CCC(C)NC(=O)CCC(O)c1cc(C)c(OC)cc1C +Cc1ccc(C(=O)N(C)C)cc1NC(=O)c1cc2ccccc2n1C +O=C(CO)N1CCN(C(=O)c2csc(-c3ccoc3)n2)CC1 +CCn1cc(C(=O)N2CCC(C(=O)OC)c3ccccc32)cn1 +O=C(COc1ccccc1)Nc1cnc(-c2ccccc2)nc1 +CC(OCC1CCCO1)C(=O)NCC(O)c1ccc2ccccc2c1 +CC(=O)N1CCN(CCNc2nc(-c3ccc(Cl)cc3)no2)CC1 +COC(=O)C1(C)CCN(C(=O)NCc2ccc(C)c(F)c2)C1 +COc1ccccc1-c1cc(C(=O)N2CCCC2)[nH]n1 +CC(O)c1ccccc1NC(=O)c1ccccc1O +Nc1nc(Sc2ccnc3cc(C(F)(F)F)ccc23)n[nH]1 +CC(NC(=O)Cc1cccs1)c1ccc2[nH]c(=O)[nH]c2c1 +CCC(CC)N(CCO)C(=O)c1cc(N)ccc1Cl +COc1ccc(C)cc1-c1cc(C#N)c(=O)n(C)n1 +COC(=O)CNc1ccc(C(=O)N2CCCC2)cc1C +Cc1ccc(C)c(N(C)C(=O)Cc2csc(C)n2)c1 +Cn1cc(S(=O)(=O)N2CCCC2)cc1C(=O)Oc1ccccc1 +C=CCN(C(=O)c1cc(C)c(C)c(S(N)(=O)=O)c1)C(C)C +CC(NS(=O)(=O)C(C)C)c1ccccc1Br +CCCCNC(=O)c1ccc(-c2ccc(S(C)(=O)=O)cc2)o1 +O=C(Cc1cccnc1)Cc1ccc(F)cc1Cl +CNc1c(NC(=O)Cc2ccccc2)c(=O)oc2ccccc12 +Cc1cc(C)n(Cc2cccc(C(=O)NCCc3cnccn3)c2)n1 +NC(=O)c1ccn(-c2ccccc2NC(=O)C2Cc3ccccc3O2)n1 +Cc1nccc(CNCc2c[nH]nc2-c2ccc(C)o2)n1 +CCCC1CN(C(=O)COC2CCCCC2C)CCO1 +CCC(C)NC(=O)CN(c1ccc(C)c(Cl)c1)S(C)(=O)=O +Cc1nc2cc(C(F)(F)F)ccc2n1CCCN1CCOCC1 +CCn1c(SCC(=O)NC2CCCCC2)nnc1C(C)C +COc1ccc(C(=O)Nc2ccccc2-c2nc(C)no2)cc1 +COCC(=O)Nc1ccc(NC(=O)c2cccc(F)c2)cc1 +COc1cccc(C(=O)Nc2oc3cccnc3c2C#N)c1 +Cc1ccc(S(=O)(=O)C(C)C(=O)NCc2ccccc2C)c(C)c1 +CC(C)c1nsc(Oc2ccc(C(N)=O)cc2)n1 +Cc1ccc(NC(=O)NC2c3ccccc3CC2O)c(C)c1 +CCC(NS(=O)(=O)c1cc(OC)ccc1OC)C(C)C +O=C(c1ccco1)n1nc(-c2ccccc2)nc1NCc1ccco1 +Cc1nc(-c2cccs2)c(CCC(=O)N2CCCC2)s1 +CC(c1ccccn1)N1CCN(C(=O)c2cc[nH]n2)CC1 +CS(=O)(=O)N1CCC(Nc2cnc3ccccc3n2)CC1 +COc1ccnc(N2CCN(C(=O)c3noc4c3CCCC4)CC2)n1 +CCn1ccc(NC(=O)Nc2cc(Cl)ccc2OC)n1 +COc1cc(CN2CCOC3CCCCC32)c(SC)cc1OC +O=C(NCCc1cccs1)C1CC(=O)N(c2ccc(F)cc2)C1 +CC1CCCCN1C(=O)CCNC(=O)COCc1ccccc1 +CNC(=O)NCC(=O)NCc1ccc(C)cc1OC(C)C +O=C(c1cccc(OCC(F)F)n1)N1CCc2cc(F)ccc2C1 +Cc1ncnc2c1CCC(=O)N2Cc1cccs1 +COc1cc(OC)c(NC(=O)CSc2ccccn2)cc1Cl +CC(C)(C)c1nnc(SCc2cnn(-c3ccccc3)c2)o1 +CC(C)c1noc(CCC(=O)N(C)c2ccc(F)c(F)c2)n1 +c1cc(NCc2nc(C3CC3)no2)cc(OCC2CCCO2)c1 +O=C(NCCc1nc(-c2ccccc2)n[nH]1)C1CCCOC1 +COCc1nc(C)c(C(=O)N(c2ccccc2C)C(C)C)s1 +O=C(CSc1ccncc1)NCc1ccc2c(c1)OCCO2 +COc1ccccc1N(CCC#N)C(=O)C(C)Sc1nncs1 +COC(=O)c1ccc(NCC(=O)c2ccc(F)c(F)c2)cc1 +CS(=O)(=O)NCCC(=O)NCc1ccc(F)cc1 +Cc1cc(-c2ccccc2C)nc(C2CCCN(S(C)(=O)=O)C2)n1 +CCN(CC)C(=O)C1CC=CCC1C(=O)Nc1ccc(C)cc1 +Cn1nnc2cc(C(=O)N3CCC(Nc4cccnn4)CC3)ccc21 +CN(C)c1ccc(-c2cc(C#N)nn2-c2ccccc2)cc1 +O=C(Nc1ccc(OC(F)F)c2ncccc12)C1CC=CC1 +Cc1nc2c(c(C(F)(F)F)n1)CC(C(=O)N1C(C)CCC1C)CC2 +COc1ccc2c(c1OC)C(C1CC(=O)C1)NCC2 +Nc1cc(-c2ccc3[nH]c(-c4ccccc4)nc3c2)n[nH]1 +CCCOCc1nc2c([nH]1)CC(c1ccccc1OC)CNC2=O +CCOC(=O)CCC1NCCc2c1ccc(OC)c2OC +O=C(CCc1nccs1)c1ccc2c(c1)OCCO2 +O=S(=O)(Oc1ccc(F)c(Cl)c1)c1cccnc1 +O=C(Nc1cn[nH]c1)NC1CCc2c(F)cccc21 +COc1ccc(S(=O)(=O)NCCn2cnc3ccccc32)cc1 +CCN1CCc2ccc(NC(=O)c3ccc(Cn4cncn4)cc3)cc21 +CC(c1nnnn1-c1ccccc1)N1CCC(Oc2ccccc2)CC1 +Cc1cc(C)c(NC(=O)CSc2nc3c(c(=O)[nH]2)CCC3)c(C)c1 +O=C(NCC1(O)CCOc2ccccc21)c1ccccn1 +O=C(Cn1nnc2ccccc2c1=O)N1CCCc2ccccc21 +N#Cc1ccc(COC(=O)c2scnc2C2CC2)cc1 +Nc1cc(-c2nc(-c3ccc(O)cc3)n[nH]2)ccc1Cl +CC(=O)N1CCSc2nnc(-c3ccco3)n21 +COCCCNC(=O)Cn1c(C(C)C)nc2ccccc21 +c1ccc2c(-c3nn4c(CN5CCOCC5)nnc4s3)c[nH]c2c1 +COc1ccc(C)cc1NC(=O)COC(=O)c1ccccc1 +Oc1ccc2c(c1Br)C(c1ccoc1)NCC2 +CC(NC(=O)c1ccco1)C(=O)Nc1cccc(-n2cnnn2)c1 +Cc1cc(C(=O)Nc2cc3c(cc2Br)OCCO3)on1 +Cc1ccc(C)c(S(=O)(=O)NCCNc2ncccc2C#N)c1 +Cc1cc(C(=O)OCc2c(C)noc2C)c2ccccc2n1 +CC(NC(N)=O)C(=O)NCCc1ccccc1Br +CNC(=O)COC(=O)c1cccnc1Nc1ccccc1F +CC(=O)N(C)CC(=O)NCCOc1ccccc1-c1ccccc1 +CC(=O)N1CCN(CC(=O)NC2(C#N)CCCC2)CC1 +CCCNC(=O)CN(C)S(=O)(=O)c1c(C)noc1C +CC(=O)NCCNC(=O)c1cn(C2CC2)c2cccc(N)c2c1=O +Cc1ccc2cccc(OC(=O)C34CCC(C3)C(C)(C)C4=O)c2n1 +Nc1nc(-c2cccc(F)c2)cc(-c2ccco2)n1 +CC(=O)N1CCC(C(=O)N(C)CCCc2ccccc2)CC1 +CCS(=O)(=O)NCC1CCN(C(=O)c2ccccc2F)CC1 +CCNC(=O)c1ccc(NC(=O)Cc2ccc(F)cc2)c(C)c1 +COc1cc(F)ccc1NS(=O)(=O)N1CCOCC1 +Cc1ccc(NC(=O)c2cccc(N(C)C)c2)cc1F +CCN(CC)C(=O)CCC(=O)N1CCCCC1c1ccc(C)cc1 +CCS(=O)(=O)NCCCN1CCOCC1C1CC1 +O=C(NCc1ccccc1)c1ccc(Cn2cccn2)cc1 +CCCOc1ncccc1CNC(=O)Nc1cccc(C#N)c1 +COc1ccc(Cc2nnc(-c3cccc(F)c3)o2)cc1OC +CC(C)S(=O)(=O)c1ccc(CC(=O)N2CCOCC2CO)cc1 +CC(C)COC(=O)Cc1csc(NC(=O)c2ccccc2)n1 +CCCCOc1ccc(C(=O)c2nccn2C)cc1 +Cc1cc(OCC(=O)NCc2csc(=O)[nH]2)cc(C)c1Cl +CCN(CCn1cccn1)C(=O)CN1C(=O)COc2cccnc21 +CCc1noc(C(C)N2CCOC(c3ccc(F)cc3)C2)n1 +C=CCn1c(CC)nnc1SCC(=O)Nc1ccc(F)cc1C +Cc1cnn(C2CCCN(C(=O)CCc3c(C)noc3C)C2)c1 +Cc1ccc(C(=O)Cn2nc(C)c(C)c(C#N)c2=O)s1 +CC(C)C(C)(C#N)NC(=O)CSc1ccc2c(c1)OCCO2 +Cc1cc(C(=O)NCC(=O)NC2CC2)c(C)n1Cc1cccs1 +O=C(CNc1cccc(OCC(F)(F)F)c1)N1CCOCC1 +NC(=O)c1ccc(NC(=O)c2cn(-c3ccccc3)nn2)cc1 +CC(C)NC(=O)c1ccc(NCc2ccsc2)cc1 +CC(C)(C)c1cc(NC=Cc2nnnn2-c2ccc(F)cc2)no1 +Cc1noc(C)c1C(C)NC(=O)NCc1ccc(-n2cccn2)cc1 +COc1ccc(CCC(=O)Nc2ccc(C(N)=O)cc2)cc1 +O=c1[nH]c(-c2ncccn2)nc2scc(-c3ccc(Cl)cc3)c12 +NC(=O)c1csc(C(=O)Nc2cccc3cn[nH]c23)c1 +O=c1ccc(-c2cccs2)nn1Cc1cccnc1 +N#Cc1ccccc1NC(=O)c1cccc(N2CCCS2(=O)=O)c1 +CC1CCCCN1C(=O)CSc1nc(-c2ccccc2)cc(=O)[nH]1 +CC(C)Sc1nc(=O)n(CCO)c2c1CCCC2 +N#CC1CCN(S(=O)(=O)c2ccccc2Cl)CC1 +CSc1ncc(C(=O)N2CCN(c3ccc(F)cc3)CC2)c(C)n1 +Cn1nc(C(C)(C)C)cc1C(=O)NCC(=O)NC(C)(C)C +CC(NC(=O)c1ccc(S(C)(=O)=O)cc1)c1ccc(Cl)cc1 +OCCSc1nccn1-c1ccc(F)c(F)c1F +Fc1cc(CN2CCOCC23CCC3)ccc1Cl +Cc1cc(N2CCC3(CCCN(C4CCOCC4)C3=O)C2)nc(N)n1 +Cc1nc(C(F)(F)F)ccc1C(=O)NCc1nnc2n1CCC2 +Cc1cccc(-c2nn(-c3ccccc3)cc2C(N)=O)c1 +CCOCCOC(=O)CN1CCNc2cc(C)ccc21 +CCN(Cc1nc2cc(OC)c(OC)cc2c(=O)[nH]1)C(C)C(C)C +COc1ccc(C2CCCN2c2nc(C3CC3)no2)c(OC)c1 +COc1ccc(F)cc1NC(=O)N(C)Cc1nnc(C)n1C +O=C(CNC(=O)c1cc2ccccn2n1)Nc1cccc(Cl)c1 +Cc1c(CNC(=O)Cn2nc(C(F)F)cc2C(F)F)cnn1C +O=C(Nc1ccc(-n2cnnn2)cc1)c1nc(-c2cnccn2)no1 +CC(C)c1nc(CN(C)Cc2cnc(N3CCOCC3)nc2)no1 +CCOc1ccc(NC(=O)CNC(=O)NC)cc1C +CC1CCC(N(C)C(=O)C2CCCN2C(=O)C2CC2)CC1 +CCOc1ccc(C(=O)C2CCN(C(=O)C3CC3)CC2)cc1 +O=C(Nc1ccccc1CN1CCOCC1)NC1CCCC1 +COC(=O)c1ccc(S(=O)(=O)N=c2[nH]cccc2C)c(C)c1 +COC(=O)CCSc1nnc2cc(C)c3ccccc3n12 +CN(C)C(=O)Cn1cc(C(=O)N(C)Cc2ccc(C#N)cc2)nn1 +Nc1nccnc1C(=O)Nc1cccc(C=Cc2ccccn2)c1 +O=C1CCCc2c1c(C1CCCCC1)nn2CCO +Cc1nc(C)c(-c2nnc(NC(=O)CC3CCCC3)o2)s1 +COc1ccnc(NC(=O)CNC(=O)c2cccc(Cl)c2)c1 +CCOc1nn(CC)cc1C(=O)Nc1ccc(F)cc1 +CCc1onc(C)c1NC(=O)N1CCCC1C(=O)N(C)C +CC(C)c1cnc(CN2CCCC(c3noc(C4CC4)n3)C2)o1 +O=S(=O)(NCC1(O)CCc2ccccc2C1)c1ccccc1 +CN1CC(C(=O)NCCNC(=O)c2ccc(F)cc2)CC1=O +O=C(CCCCO)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cn1cc(S(=O)(=O)N(Cc2ccc(Cl)cc2)C2CC2)cn1 +COc1ccc(C2CCCN2S(=O)(=O)N2CCOCC2)cc1 +CC1Oc2ccc(-c3cnnc(N)n3)cc2N(C)C1=O +COc1cccc2c(=O)c(C(=O)NCc3nnc4ccccn34)c[nH]c12 +N#CCC(=O)Nc1ccc(C(=O)N2CCc3ccccc3C2)cc1 +CCCCC(=O)NCC#Cc1ccc(N2CCCCC2=O)cc1 +COc1ccc(S(=O)(=O)NC(C)C(=O)N2CCCCC2C)cc1 +COc1cccc(C(N)=O)c1OCC(=O)c1cc(C)n(C)c1C +CC(=O)NCCNC(=O)c1cccc(Br)c1N +CNc1nnc(-c2cnn(-c3ccc(C)cc3)c2C)s1 +CC(Cn1ccnc1)NS(=O)(=O)Cc1ccccc1 +Cc1cc(Cl)ccc1OS(=O)(=O)c1ccc(C(N)=O)cc1 +COC(=O)CN(Cc1ccccc1C)C(=O)c1ccn(C(C)C)n1 +CCCNC(=O)CNc1cc(C)c(Cl)cc1OC +COC(=O)C(C)CNC(=O)Nc1cccc(Cn2nc(C)nc2C)c1 +CCOc1ccc(NC(=O)N2C3CCC2COC3)cc1 +Cc1ccccc1S(=O)(=O)NCc1nc2cccnc2n1C +O=C(CN1CCOCC1C1CC1)NCc1cc(F)cc(F)c1 +CCOc1cc(CCC(=O)N2CCCCC2)cc(N)c1O +Cc1ccc(CNC(=O)C2CCCN(C(=O)N3CCCC3)C2)cn1 +O=C(Oc1cccc(F)c1)C1CCN(C(=O)c2ccoc2)CC1 +Cc1ccc(C(CN2CCOCC2)NC(=O)Nc2cc(C)on2)cc1 +COCc1csc(NC(=O)c2cccc(-c3n[nH]c(C)n3)c2)n1 +CCc1nnsc1C(=O)NCC1CCN(c2ccccc2)C1 +CC1CCCN(C(=O)NC2CCSc3ccc(F)cc32)C1 +C#CCOCCC(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +CNC(=O)C1CN(C(=O)c2ccc(OC)c(OC)c2)CC12CCCC2 +COc1ccc(N2CC(C(=O)N3CCCC(O)C3)CC2=O)cc1 +c1ccc(-c2cc(Nc3ncccn3)nc(-c3ccncc3)n2)cc1 +CNC(=O)c1ccccc1C#CCNC(=O)COc1ccccc1F +COc1ncc(Cl)c(N2CCCC(c3nc(C)no3)C2)n1 +CCOc1ccccc1NC(=O)c1cccn1-c1cccnc1C +CC(C)Oc1cc(C(=O)NC2CC2)cc2occc12 +CCSc1cc(C(=O)NCc2nc3ccccc3n2C)ccn1 +Cc1c(Br)c(-c2nc3c4ccccc4ncn3n2)nn1C +Fc1cncc(C2NCCc3c2cc(F)c(Cl)c3F)c1 +CN(CC1CCN(C(=O)OC(C)(C)C)C1)c1nccs1 +O=C(NCC(=O)N1CCCCC1)c1ccn2cncc2c1 +COCc1ccc(C(=O)NCc2ccccc2F)cc1 +Cc1cc(C)c(NC(=O)C(C)c2nc(CO)cs2)c(C)c1 +CC(C)CN(CCC#N)C(=O)Nc1ccc(Cl)cc1 +COC(C)c1cccc(NC(=O)c2ccn(-c3ccccc3F)n2)c1 +CC1=C(c2ccc(F)cc2)S(=O)(=O)N=C1Nc1c(C)cccc1C +CCOc1ccc(OCC(=O)NCC#Cc2ccccc2F)cc1 +Cn1nnnc1SCCNC(=O)c1c[nH]nc1C1CCCCC1 +CCc1nc(COC(=O)C2CCCN2C(=O)OC)cs1 +O=C(CCNC(=O)c1ccc(F)cc1F)Nc1ccc2c(c1)COC2 +Cc1cnc(NC(=O)CCCNc2ncccn2)s1 +CC(=O)NC(C)C(=O)Nc1nc(-c2ccc3ccccc3c2)cs1 +COC(=O)N1CCCC(C(=O)N(C)CC(O)C2CC2)C1 +COc1cc(NC(=O)C2CCC(=O)N2)cc2ccccc12 +COc1ccc(Cc2nnc(C(=O)N3CCOCC3)o2)cc1OC +O=C(NCc1nncn1C1CC1)Nc1ccc(-c2csnn2)cc1 +Cc1ccc(CNC(=O)COc2cccc3ccc(C)nc23)cc1 +NC(=O)Nc1cccc(CNC(=O)c2cnc(-c3ccco3)s2)c1 +CC(=O)c1ccc(C#CCNC(=O)c2ccccc2F)cc1 +COc1ccc(-c2cn3ccn(-c4ccccc4)c(=O)c3n2)cc1OC +CCn1nc(-c2nn3c(-c4cccs4)nnc3s2)cc1C +COC(=O)CCCN1C(=O)CNc2cc(F)c(F)cc21 +O=C(CC1OC(=O)c2ccccc21)Nc1ccccc1Cn1cccn1 +CN1C(=O)C2(N=C(N)NC(N3CCOCC3)=N2)c2ccccc21 +CCC(=O)NCCc1cc2ccc(C)c(C)c2[nH]c1=O +Cn1c(=O)c(C(=O)Nc2cccc(Cl)c2)nc2ccccc21 +CCC(C)c1ccc(OCC(=O)NCc2cccnc2)cc1 +c1coc(CNc2nnc(SCc3nc(C4CC4)no3)s2)c1 +FC(F)c1cc(-c2cccs2)nc2ccnn12 +CCn1ccnc1CS(=O)(=O)c1ccc(F)c(F)c1 +CCOC(=O)N1CCC(NC(=O)Nc2ccc(F)c(Cl)c2)CC1 +O=C(CC1CCCC1)Nc1nnc(-c2ccccn2)[nH]1 +Cc1ccc(C)c(SCC(O)c2ccc(S(C)(=O)=O)cc2)c1 +O=C(CC1C=CCC1)Nc1ccccc1NC(=O)c1ccoc1 +Cc1cc(C)cc(C(=O)Nc2cc(C(N)=O)ccc2N2CCCC2)c1 +COc1ccc(C)cc1CCNS(=O)(=O)c1ccc2c(c1)CCO2 +O=C(NCc1ccncc1)N(Cc1ccc(O)cc1)CC1CC1 +CCC(CO)NC(=O)c1nn(-c2ccc(C)cc2)nc1CO +Cc1c(C(=O)N2CC3CC(C)OC3C2)oc2ccccc12 +CCc1nnc(NC(=O)CNC(=O)c2ccco2)s1 +NC(=O)c1ccc(CNc2ccc3c(c2)CCC3)cc1 +Cc1n[nH]c(C)c1N1CCN(Cc2ccccc2Cl)CC1 +COc1ccc(COC(=O)c2ccc(N3CCCC3=O)cc2)cc1F +COC(=O)c1ccc(Nc2ncc(Br)cn2)cc1 +CC(C)NC(=O)c1cccc(NC(=O)c2cc3ccoc3cn2)c1 +Cc1ccc(C(=O)N2CCn3nnc(COc4cccnc4)c3C2)cc1 +O=C(COC(=O)C1CCC1)c1c[nH]c2ccccc12 +CCn1cc(C(=O)Nc2ccc(OC(C)C)cc2F)cn1 +Cc1ccc(C(C)NC(=O)c2ccc(N3CCOC3=O)cc2)cc1F +O=C(c1ccc(Br)cc1O)N1CCC2(CC1)OCCO2 +O=C(Nc1ccc(-c2cn3cccnc3n2)cc1)c1cnccn1 +CC(=O)NC1CCCN(S(=O)(=O)c2cc(C)sc2C)C1 +CCn1nc(-c2nc(-c3ccc(S(C)(=O)=O)cc3)no2)ccc1=O +Cc1cccc(Cl)c1NC(=O)C1CC(=O)N(Cc2ccccc2)C1 +CC(=O)N1CCCc2cc(NC(=O)NCCc3cnn(C)c3)ccc21 +Cc1n[nH]c(-c2cccc(CNC(=O)CNC(=O)c3ccccc3)c2)n1 +Cc1cc(C)n2c(CNC(=O)Cc3ccccc3Cl)nnc2n1 +CC(Oc1ccccc1)C(=O)N1CCN(Cc2cccs2)CC1 +CC(=O)Nc1ccc(F)c(C(=O)NCCOc2cccnc2)c1 +CC(=O)Nc1cccc(NC(=O)Nc2ccc3c(c2)OCO3)c1 +COc1cc(NC(=O)c2cccc(N)c2)cc(OC)c1 +CCc1[nH]nc(NC(=O)Nc2nnc(-c3ccccn3)s2)c1C +Nc1oc2ccc(F)cc2c1-c1nc2ccccc2[nH]1 +CCC(C)n1nccc1NC(=O)c1cc(OC)c(OC)c(OC)c1 +N#Cc1ccc(C(=O)OCC(=O)NC2CCCC2)cc1 +CC1(C(=O)N2CC(CN3CCOCC3)c3ccccc32)CCCO1 +NS(=O)(=O)NCC1(c2ccc3c(c2)OCCO3)CCCC1 +CCCNC(=O)CNc1cccc(C(=O)N2CCOCC2)c1C +COCCCN1C(=O)c2[nH]nc(-c3ccccc3)c2C1c1ccccc1 +N#Cc1ccc(NC(=O)NCc2ncc[nH]2)cc1C(F)(F)F +Cc1ccc(S(=O)(=O)Oc2cccc3cccnc23)cc1 +O=c1cc(CO)occ1OCc1cccc(Cl)c1 +Cc1cc(C(=O)OCC(=O)Nc2ccccc2C(F)(F)F)on1 +CN(Cc1cccc(C(N)=O)c1)c1ccc2ccccc2c1 +CCC(CO)NC(=O)NCCNC(=O)c1ccc(C)c(F)c1 +Cc1c(CN2CCOCC2CC(=O)c2ccccc2)cnn1C +CC1(C)C(=O)NCCN1Cc1cc(Cl)cc(Cl)c1 +CCc1nn(-c2c(F)cccc2F)c2c1CNCC2 +Cc1cccc(-c2noc(-c3cccc(N)c3)n2)c1 +CC(=O)c1ccc(OCC(=O)Nc2nccn(C)c2=O)cc1 +O=C(CCc1cc2n(n1)CCN(c1ncccn1)C2)NC1CCCC1 +CS(=O)(=O)NCCNC(=O)c1ccc2cc[nH]c2c1 +O=C(NCc1ccnc(OC2CCC2)c1)c1cc(-c2ccccc2)on1 +NC(=O)c1ccccc1NC(=O)Nc1ccccc1 +CCN(CC(=O)OC)S(=O)(=O)c1cccc(N)c1C +CC(C)COCC1CN(S(=O)(=O)N(C)C)Cc2cncn2C1 +COc1cc(Cl)c(C)cc1-n1nnc(CO)c1C(C)C +O=C(NC1CCc2c(F)cccc21)N1CC2CCC1C2 +Cc1cc(C)n2nc(C(=O)Nc3cccc(Cl)c3)nc2n1 +Cc1nc(-c2ccc(S(=O)(=O)NCc3ccoc3C)cc2)co1 +CCCC(C)N1CC(c2nc(Cc3noc(C)n3)no2)CC1=O +CN1CCN(C(=O)c2scnc2C2CC2)c2ccc(F)cc21 +CC(C(=O)Nc1c[nH]c(=O)[nH]c1=O)(C(F)(F)F)C(F)(F)F +O=C(CCn1cnnn1)N1CCCC1c1nc(-c2ccccc2)no1 +CCOC1CCCN(C(=O)CCn2c(=O)[nH]c(=O)c3ccccc32)C1 +CC(C)NC(=O)Nc1ccccc1N1CCOC1=O +Cc1ccc(-n2nc(C)c(C(=O)N(C)Cc3ccco3)n2)c(C)c1 +Fc1cccc(-n2cc(-c3noc(-c4cccnc4)n3)nn2)c1 +Cc1ccccc1-n1cnnc1SCC(=O)Nc1ccccc1 +OC(Cc1cccnc1)c1cnc2ccccc2c1 +CCC(C)(c1nnnn1-c1c(C)cccc1C)N1CCOCC1 +Cc1nc(COc2ccc(C(=O)c3ccccc3)cc2)no1 +O=C(NCCO)Nc1ccc2nc(-c3ccccn3)oc2c1 +CN1C(=O)C(C)(C)c2c(Br)cccc21 +Cc1ccc(CNC(=O)c2nc[nH]c2C(=O)NCCC(C)C)cc1C +CC(C)(C)NC(=O)CCC(C#N)c1ccc(F)cc1 +C=CCn1c(=O)c2c(nc3n2CCN3c2cccc(C)c2)n(C)c1=O +CC(C)CC(C)OCCC(=O)N1CCc2[nH]ncc2C1 +CN1CCN(C(=O)CCCc2nc(-c3ccc(Cl)cc3)no2)CC1 +COc1ccc(-c2nc3sc(C(C)(C)C)nn3c2CO)cc1 +Cc1ccc(S(=O)(=O)N2CCCn3nccc32)cc1C +CCOC(=O)N1CCCC(C(=O)N2CCCSc3ccccc32)C1 +CCCn1c(SCC(=O)Nc2nccs2)nnc1C(C)C +O=C(c1cccs1)N(Cc1cccnc1)c1ccc(F)cc1 +CC1(C)C(=O)NCCN1C(=O)Cc1csc(-c2cccs2)n1 +CCc1ccccc1NC(=O)Cn1c(C)nc2ccccc2c1=O +CCCCNC(=O)C1CCC(C)N(C(=O)Nc2ccccc2OC)C1 +Nn1c(SCc2n[nH]c(=O)[nH]2)nnc1C(F)(F)F +Cc1cn(-c2ccccc2Cl)nc1NC(=O)Cc1ccon1 +O=c1c2c3c(sc2ncn1CC(O)c1ccc(F)c(F)c1)CCC3 +O=C(NC1CCN(C(=O)C2CCC2)C1)C1CCCC1 +CC(=O)Oc1ccc2c3c(c(=O)oc2c1C)CCC3 +O=C1CCC(C(=O)NCC#CCOc2ccccc2Cl)N1 +CC(NC(=O)C1CC=CCC1)c1nc(-c2ccc(F)cc2)no1 +CCC(CO)NC(=O)Nc1ccccc1N1CCCC1=O +CCOC(=O)c1cc2c(ccn2C)n1CC(=O)N1C(C)CCCC1C +O=C(C1CCC1)N1CC2CCC(C1)N(C(=O)CCc1ccncc1)C2 +CCC(C)CN1C(=O)C(=O)c2cc(F)cc(Br)c21 +CC(=O)c1cccc(NC(=O)Cn2cnc3c(C)cccc3c2=O)c1 +CCn1ncc2cc(C(=O)n3cnc4ccccc43)c(N)nc21 +C#CCOCC1CCCN(C(=O)c2ccc(C(F)(F)F)cc2)C1 +O=C(NCc1ccccn1)N1CCCC1c1ccsc1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)Cn1ccc(=O)[nH]c1=O +CCc1nc(NC(=O)c2c(C)n[nH]c2C)sc1C +CCc1nnc(SCC(=O)Nc2c(F)cccc2F)n1N +CCn1nc(-c2ccc(F)cc2F)cc(C#N)c1=O +CC(=O)N1CCC2(C1)c1ccccc1S(=O)(=O)N2CCC(C)C +COC1CCCOC12CCN(c1nc(N(C)C)ns1)CC2 +C=C(C)COC(=O)CCNC(=O)Nc1ccccc1 +COC(=O)c1ccc(CS(=O)(=O)N(C)CCO)cc1 +COCCNC(=O)NCC1(c2cccs2)CCOCC1 +COc1ccccc1OCCNC(=O)c1cccc(F)c1 +CCNC(=O)CN1CCN(C(=O)C2CCN(C(C)=O)CC2)CC1 +CCCC(O)c1cc(Cl)cc2c1NC(=O)C2C +COCCNC(=O)Cn1c(=O)c2cccn2c2ccccc21 +CC(C)(C)C(C#N)NC(=O)CNC(=O)c1cc2ccccc2[nH]1 +Cc1nc(C)n(Cc2coc(-c3cccc(F)c3)n2)n1 +COc1ccc(Br)c(NCC(=O)N2CCOCC2)c1 +CCCCc1nnc(NC(=O)c2nc3nc(C)cc(C)n3n2)s1 +CCCNC(=O)NCC1(OC)C2CC3CC(C2)CC1C3 +CCCn1ccnc(N(CCO)C2CCCC2)c1=O +CCOc1ccccc1NC(=O)C1CC(=O)N(C2CCC(C)CC2)C1 +Cc1n[nH]c(C)c1NC(=O)C(C)Oc1ccc(Cl)cc1 +CC(=O)c1c(F)cccc1NC(c1ccccc1)c1nccn1C +N#CCCn1c(-c2ccc(Cl)cc2)ccc(C#N)c1=O +CCn1cc(CCC(=O)NCC(=O)C(C)(C)C)c(C)n1 +CCCN(CCC)S(=O)(=O)c1ccc(C(N)=O)cc1 +COCCCNC(=O)c1cc(Cl)ccc1OC +Cc1ccsc1C(=O)Nc1cnn(-c2ccccc2F)c1 +CCc1ccc(S(=O)(=O)Nc2ccccc2C(=O)NC2CC2)cc1 +Nc1cccc(C(=O)CCN2CCc3ccccc3C2)c1 +Cc1cc(C(C)(O)CNC(=O)c2cccnc2-n2cccn2)c(C)o1 +CC(C)(C)S(=O)(=O)c1cnc(-c2ccc(Cl)cc2)nc1N +Cc1nc2c(NCC3(c4cccc(F)c4)CCOCC3)ncnc2o1 +Cc1ccc(N2CCCC2=O)c(C(=O)NC(C)c2ccncc2)c1 +CCn1cc(C(=O)Nc2nc(-c3cccc(OC)c3)ns2)cn1 +CCNC(=O)C(C)NC(=O)NC(C)c1ccccc1C(F)(F)F +COc1ccccc1S(=O)(=O)NCCc1ccoc1 +O=C(NCc1ccccc1Cl)NC1CCN(CC(F)(F)F)C1 +Cc1cc2c(c(=O)[nH]1)C(c1cccc3ccccc13)CC(=O)O2 +CC(C)NC(=O)c1cc(OCC(=O)N2CCOCC2)n(C)n1 +CC(=O)c1ccc(NC(=O)Cc2csc(-c3ccccn3)n2)cc1 +O=C(c1cc(C2CC2)nc2ccccc12)N1CCC1 +CN(C(=O)c1nn(C)c2ccc(F)cc2c1=O)c1ccccc1 +COC(=O)C(CNC(=O)c1ccon1)Oc1ccc(F)cc1 +CC(NC(=O)c1cn2ccccc2n1)c1ccc(F)cc1F +COc1cccc(C2CCCN2C(=O)c2cc(C)sc2C)c1 +Cc1ccncc1NC(=O)N(C)CCOc1cccc(Cl)c1 +O=C(Cc1ccccc1O)Nc1ccc(N2CCCC2)nc1 +Cc1ccc(C(=O)OC(C)c2ccc3c(c2)OCO3)o1 +Cc1cccc2[nH]c(CNC(=O)NCCCC3CCCCO3)nc12 +Cc1nn(C)c(C)c1C(=O)OCC(C#N)Cc1ccccc1 +COc1cc(NC(=O)Nc2cccnc2)cc(OC)c1 +c1cnc(N2CCN(c3cncc(-n4cccn4)n3)CC2)nc1 +Cc1noc(C)c1CCCNS(=O)(=O)c1cc(F)c(F)cc1F +Cc1ccccc1CN(C)C(=O)CSc1nccn1C +COCCCNC(=O)CN(C)C(=O)c1cc(Br)cn1C +COc1ccccc1CCN(C)S(=O)(=O)c1ccc(C#N)cc1 +CC1CCCCC1NC(=O)CNC(=O)Cc1ccccc1 +CCOC(=O)CN(C1CC1)S(=O)(=O)c1ccc(F)cc1Cl +O=C(Nc1ccccn1)c1occc1CSc1ccccc1 +O=C(c1cn2ccsc2n1)N1CCN(c2ncccn2)CC1 +Cc1ccc(CC(=O)Nc2ccc(C(=O)NC3CC3)cc2)cn1 +O=C(NCCc1ccccc1)c1n[nH]c2c(Cl)cccc12 +Cc1ccc(-c2ccc(S(=O)(=O)N(C)C)cc2)cc1O +Cc1ccc(OCC(=O)OCC(=O)NC(C)C)cc1C +Nn1c(SCC(=O)OC2CCCC2)nnc1-c1ccccc1O +COCCNC(=O)N1CCC(NC(=O)CC2CCCC2)CC1 +COc1ccc(OC)c(C(=O)Cn2nnc(-c3ccc(F)cc3)n2)c1 +Cc1c(NC(=O)CCC2CCCO2)cccc1C(=O)N1CCOCC1 +CCN(CC(=O)NC(C)C)C(=O)C(C)(C)c1ccc2c(c1)OCCO2 +COC(=O)Nc1ccc(NC(=O)COC2CCCCC2)cc1 +O=C(CCNC(=O)C1CCCCC1)Nc1ccccc1F +O=C(Nc1nnc(C2CC2)s1)N1CCC(O)(C(F)(F)F)CC1 +CCCCc1ccc(NC(=O)c2ccc(S(N)(=O)=O)cc2)cc1 +CCCCOC(C)C(=O)N1CCc2cc(F)ccc2C1 +Cn1cccc(NC(=O)NC(C)(C)CCO)c1=O +CCOC(=O)C1=C(C)C(C(=O)Nc2ccc(C)cc2O)=NC1C +COc1ccc(C=C2OC(=O)c3c2cc(C)[nH]c3=O)c(OC)c1OC +Cc1nn(Cc2ccc(Cl)c(Cl)c2)c(C)c1NS(C)(=O)=O +C#Cc1cccc(NCC(=O)c2c(N)n(CCC)c(=O)n(C)c2=O)c1 +O=C(Nc1ccccc1)c1nnc(C(=O)NC2CCCCCC2)s1 +Cc1ccc(NC(=O)Cn2ccn(Cc3ccccc3)c(=O)c2=O)cc1 +Cc1cc(C(F)(F)F)nc(SCc2ccccn2)c1C#N +CCOC1CCCN(C(=O)c2cc(Br)c[nH]2)C1 +C=CCc1ccc(OCC(=O)Nc2cc(F)ccc2F)c(OC)c1 +CC1CN(C(=O)c2nc(NCc3ccccc3)ncc2Cl)CCO1 +Cc1nc(SCc2n[nH]c(=O)[nH]2)c2c3c(sc2n1)CCC3 +Cc1nc2n(n1)CC(CC(=O)Nc1cc(Cl)ccc1C)C(=O)N2 +COc1cc(NC(=O)Nc2ccc3c(c2)C(=O)NCC3)cc(OC)c1 +O=C(Nc1sc2c(c1C(=O)N1CCOCC1)CCCC2)C1CCC1 +COCc1cccc(C(=O)NC(C(=O)OC)c2cc(F)ccc2F)c1 +Cc1ncccc1C(=O)N1Cc2cnc(CC(C)C)nc2C1 +O=C(Nc1cccc2cccnc12)c1cccc(-n2cccc2)c1 +Cc1csc(CNC(=O)CCn2cnc3sccc3c2=O)n1 +CCC(C)C(=O)Nc1ccc(S(=O)(=O)NC(C)(C)C)cc1 +CC(C)NC(=O)Nc1cccc(C(=O)OCC2(C)COC2)c1 +COc1ccccc1NC(=O)CCn1c(C)nc2ccccc21 +O=C(COC(=O)c1ccc(O)cc1)Nc1ccc(OC(F)F)cc1 +COc1cc(C(=O)N2CCc3ccc(N)cc32)ccc1C +CC(=O)c1cc2c(cc1NC(=O)c1cccnc1)OCO2 +Cc1ccc(C)c(-c2ccc(C(=O)NC(C)(C)CO)o2)c1 +C=CCN(CCc1ccccc1)C(=O)NC(C)c1nncn1C +COc1c(C)cc(C)cc1C(=O)CCN1CCOCC1 +CC1CCCCC1NC(=O)CNc1cccc(C#N)c1 +Cc1nc(CC(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)cs1 +COC(=O)c1ccc(N2CCN(Cc3cccnc3C)C(C)C2)cc1 +CCN(CCC#N)C(=O)COc1ccc(Cl)cc1 +COc1ccc(-c2nc(CS(=O)c3cccc(C)c3)no2)cc1 +Cc1cc(NC(=O)C(C)Sc2nc(C)cs2)on1 +COc1ccc(Nc2nc3cc(OC)c(OC)cc3[nH]2)cc1 +O=C(CC1CCc2ccccc21)NCc1ccc(N2CCCC2=O)cc1 +O=c1[nH]c(-c2ccco2)nc2sc3c(c12)CCCC3 +CC1CC1c1ccc(CNc2ccc(=O)n(C)c2)o1 +CCn1c(SCC(=O)Nc2cccc(SC)c2)nnc1C1CC1 +O=S(=O)(NCc1cscn1)c1ccc2c(c1)OCCCO2 +Nc1cc(NS(=O)(=O)c2ccccc2)ccc1Cl +CCn1c(N)c(N(C)CC2CCC(C)(C)CC2)c(=O)[nH]c1=O +CCCC1CN(C(=O)C2CC(=O)N(c3ccc(OC)cc3)C2)CCO1 +CCCCC(=O)Nc1ccc2c(c1)CCN2C(C)=O +CCC(=O)Nc1ccc(C(=O)CCC(=O)OC)cc1 +CCCCOc1ccc(NC(=O)c2onc(C#N)c2N)cc1 +CCOC(=O)C(C)NC(=O)C(C)Oc1ccc(C)cc1 +COC(=O)c1cc(C)sc1NC(=O)c1cc(C)oc1C +CC(C)Oc1ncc(C(=O)N(C)Cc2ccc(O)cc2)cc1Cl +CCN(c1ccc(OCC(=O)NC)cc1)S(=O)(=O)c1ccccc1 +COCCN(CC(F)(F)F)C(=O)c1oc2ccc(OC)cc2c1C +O=C(c1cccc(Cl)c1)N1CCCC1c1nc2ccccc2[nH]1 +Cc1ccc(C)c(NC(=O)Cn2cnc(C)cc2=O)c1 +CCNC(=O)c1ccc(CNC(=O)NCCOC)cc1 +CCn1nccc1C1CCCN1C(=O)c1c(Cl)cnn1C +CC(=O)c1cccc(NC(=O)c2cccc(S(=O)(=O)C(C)C)c2)c1 +Cc1ccccc1N1CCN(C(=O)c2cc(C)c(C)[nH]c2=O)C(C)C1 +CC(C)CC(OC(=O)c1ccco1)C(=O)NC1CCCC1 +Cc1cc(C)c2c(c1Br)OCC(C)C(=O)N2 +COc1ccc(-c2nc(C)c3ccccn23)cc1N +Cc1cc2c(cc1F)C(c1ccc(=O)[nH]c1)NCC2 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)c1scnc1C1CC1 +O=C(NCCCn1ccnc1)c1ccc(NC(=O)C2CC2)cc1 +Cc1ccc(OCC(=O)Nc2cccnc2)cc1C +COC(=O)C1=C(C)C(C(=O)C(C)OC(=O)c2ccc(O)cc2)=NC1C +CCCn1cnnc1C1CCCCN1C(=O)c1ccco1 +CC(C)(C)C(=O)N1CCC(Oc2ccccn2)CC1 +Fc1ccc(Cn2nccc2-c2ccncc2)c(Br)c1 +NC(=O)c1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 +CCOC(=O)c1sc2ncn(CC(=O)N3CCCC3)c(=O)c2c1C +CCOc1ccc(-c2nnc(NC(=O)c3ccnn3C)o2)cc1 +COc1ccc(Br)cc1NC(=O)c1ccc(=O)n(C)c1 +OCCNc1ccc2nnc(-c3ccc(Br)cc3)n2n1 +Cc1cc(NC(=O)COc2cc(Cl)cc(Cl)c2)no1 +CNS(=O)(=O)c1ccc(C(=O)NCCOc2cccc(C)c2)o1 +Cc1cc(S(=O)(=O)NCc2csc(=O)[nH]2)c(C)s1 +O=C(c1ccccc1)C1CCCCN1C(=O)c1ccccc1 +CS(=O)c1ccc(C(=O)NCC(=O)NC2CC2)cc1 +COc1ccc(CCOc2cc(C)c(N)cn2)cc1F +CC(C)c1nc(CN2Cc3ccccc3CC2C(N)=O)co1 +COc1ccc(OC)c(NC(=O)C2CCCN(c3ncccn3)C2)c1 +CCCC(=O)N1CCCC1C(=O)N(C)c1nc(C)cs1 +Cc1sc2c(=O)n(C(C)C)cnc2c1C(=O)Nc1ccccc1F +Cc1cc(-c2nnc(NCC(C)C)s2)c(C2CC2)o1 +CC1=C(C(=O)OCC(C)C)C(c2ccc(C)o2)NC(=O)N1 +Cc1[nH]c2ccnn2c(=O)c1CC(=O)N(C)c1cccc2ncccc12 +O=C(NCCC(=O)N1CCCc2cc(Cl)ccc21)c1ccoc1 +O=S(=O)(NC1CC1)c1ccc(SCCO)cc1 +CCCCN1C(=O)CCc2cc(NC(=O)COC)ccc21 +CCN(C)S(=O)(=O)c1ccc(OCC(F)(F)F)nc1 +CCCn1c(C)nnc1SC(C)c1nc(N)nc(N(C)C)n1 +O=C(c1ccc2[nH]ccc2c1)N1CCn2cc(Cn3cccn3)nc2C1 +CCOc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)cc1 +CCN(CC)C(=O)C(C#N)CCOc1ccc(C)cc1C +CC(COc1ccc(Cl)cc1)NC(=O)c1ccco1 +C#CCn1c(=O)c(C)nc2cc(OC)c(OC)cc21 +COc1ccc(S(=O)(=O)Nc2ccc(F)cc2)cc1F +Cc1cccc(CC(=O)Nc2ccc(CC(=O)N3CCCC3)cc2)c1 +CN(CC(=O)NC1CCCNC1=O)c1ccccc1 +CCn1nccc1C(=O)NC1CCN(c2nnc3ccccn23)CC1 +CCC1CCC(NC(=O)CCn2cc(C)cn2)CC1 +Cc1ccnc(NC(=O)CCCSc2ccccc2)c1 +Cc1ccccc1C(C)NC(=O)CCn1cc(S(N)(=O)=O)cn1 +CCC(Sc1nccn1C)C(=O)Nc1nnc(C)s1 +CCOc1c(OC)cc2c(c1Cl)C(C1CC1)NCC2 +Cc1ccc(S(=O)(=O)N2CCCC2c2nc(C)no2)c(C)c1 +CCNC(=O)C1CCN(C(=O)NCCCOC)CC1 +O=C(NCc1nc(-c2cccc(Cl)c2)no1)C1CCOCC1 +Cc1ccc(C(=O)N(C)CC(=O)Nc2cc(C)on2)cc1 +Cc1ncsc1C(=O)NC1CCN(C(=O)Nc2ccccn2)CC1 +COCCOc1ncnc(NCC2CCCO2)c1N +N#Cc1c(N)nc2nc(N3CCOCC3)[nH]c(=O)c2c1-c1ccccc1 +CC(C)N1CC(C(=O)NCCCn2cccn2)CC1=O +CCCOc1cccc2c1C(c1ccc(C)nc1)NCC2 +CC(C)(C)CCNS(=O)(=O)c1cc(F)cc(F)c1 +Cn1cnc(CNC(=O)N(Cc2ccccc2)C2CCCCC2)n1 +CC(NC(=O)NCc1ccccn1)c1ccc(F)cc1Cl +CC(=O)c1c[nH]c(C(=O)NCC2CN3CCCCC3CO2)c1 +Nn1c(C(=O)N2CCCC2)nc2ccccc2c1=O +C=CCN1C(=O)NC(c2ccc3c(c2)CCO3)C(C(=O)OC)=C1C +Cc1occc1C(=O)Nc1nc(-c2ccc3c(c2)CCC3)cs1 +COc1ccc(NC(=O)NCCNC(C)=O)c(Cl)c1 +O=C(CCc1ccsc1)N1CCN(CCn2cncn2)CC1 +COc1ccc(F)c(NC(=O)c2cc(C3CC3)nc3onc(C)c23)c1 +COc1ccnc(NCc2ccccc2CN2CCOCC2)n1 +Cc1ccc(S(=O)(=O)C(C)C(=O)Nc2ccccc2C)cc1C +NC(=O)CC1CCN(C(=O)NCc2nc3ccccc3s2)CC1 +CC=CC=CC1NCCc2cc(O)c(OC(F)F)cc21 +Cc1cc(C(=O)Nc2nc(C)c(SCC(N)=O)s2)no1 +CNC(=O)c1sc(-c2cc(OC)ccc2Br)nc1C +CCOc1ccccc1-c1cn2nc(COC)sc2n1 +O=C(Cn1cc(Br)cn1)c1ccc2c(c1)OCO2 +Cc1cc(C(=O)NC(C)CN2CCOCC2)on1 +O=C(CCc1ccc(F)c(F)c1)N1CCN(Cc2ccccn2)CC1 +C#CCN(Cc1cccnc1)C(=O)NC(CC)c1ncc(C)s1 +O=C(CNC(=O)c1ccccc1)Nc1ccc(F)c(C(F)(F)F)c1 +CN(CC(O)C1CC1)C(=O)COc1ccc2ccc(=O)oc2c1 +CCC1CN(Cc2ccc3c(c2)CCCN3)CCO1 +Cc1csc(C(C#N)C(=O)C2CC2c2ccccc2Cl)n1 +CCOC(=O)CN(CC)C(=O)c1cc(N)c(C)s1 +Cc1ccccc1-n1c(N)cc(=O)n(Cc2cccs2)c1=O +CC(C)COC1CCN(C(=O)c2nccc3ccccc23)CC1 +Cc1noc(C2CCN(C(=O)Cc3csc(C)n3)CC2)n1 +Cc1cc(C)n(-c2ccc(C(=O)N(C(C)C)C3CCC3)cc2)n1 +Cc1nc(-c2cccc(C(=O)Nc3cccc(C(N)=O)n3)c2)cs1 +Cn1ncc2c1CCCC2NS(=O)(=O)c1cccs1 +Cc1nsc2nc(-c3ccc(F)cc3Cl)oc(=O)c12 +O=C1CC2(CCN(C(=O)c3cc(C4CC4)on3)C2)Oc2ccccc21 +Cc1cc(S(=O)(=O)N2CCC(C#N)CC2)ccc1Cl +N#Cc1cc(-c2ccccc2)sc1NC(=O)c1ccccn1 +Cc1ccc(NC(=O)N2CCN(C(=O)C(C)(C)C)CC2)cc1C +CCOC(=O)C=C(NCc1c(C)nn(C)c1C)C(F)(F)F +CC(=O)N1CCN(C(=O)CNc2c(F)cccc2NC(C)C)CC1 +Cc1nnnn1-c1cccc(NC(=O)CCc2ccco2)c1 +CCC1CCCN(C(=O)NCc2cccc(OCC(=O)N(C)C)c2)C1 +COC(=O)c1cccc(C(=O)Nc2ccc(C)cc2)c1 +CCOc1ccccc1CNC(=O)c1ccc(OC)nc1 +CC(C)Oc1ccc(C(=O)Cn2cc(N)cn2)cc1Cl +CC(C)c1cc(C(=O)NCc2csc3c2CCCC3)n(C)n1 +CCOc1cc(Br)c2nc(NC)sc2c1 +O=C(NCc1ccc2sccc2c1)C1CCCCn2nnnc21 +CCCCS(=O)(=O)N(C)c1ccc(NC)cc1F +CCc1nc(C2CCCN(C(=O)C3CCc4ccccc43)C2)no1 +Cc1noc(C(C)C)c1C(=O)NCc1cccc(N(C)C)c1 +CC(Oc1ccc2oc3ccccc3c2c1)C(N)=O +O=C1CC2(CCN(C(=O)c3ccccc3N3CCOCC3)CC2)CN1 +COc1ccc(C(=O)OC(C)C)c(OC)c1OC +CNS(=O)(=O)c1cccc(C(=O)OCc2cccc(F)c2)c1 +CCc1noc(C)c1C(=O)NCC(C)(C)c1ccccc1OC +CC(C)CCc1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)cc1 +CC(=O)OCc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +CC(=O)c1ccc(NC(=O)Cn2nc3ccccn3c2=O)cc1 +Cc1ccc(C(=O)c2ccc(N(C)C)c(N)c2)cc1 +O=C(c1ccc2c(c1)OCO2)c1cc2ccc(O)cc2oc1=O +COC(=O)C1(N(C)C(=O)Cc2c[nH]c3ncccc23)CCCCC1 +CC(OC(=O)c1ccccc1C(=O)c1cccs1)C(=O)N(C)C +CNc1ncc(C(=O)N(C)Cc2cc(Br)cs2)s1 +COC(=O)C(CC(C)C)NS(=O)(=O)c1ccc2c(c1)OCCO2 +CCn1nc(C)c(S(=O)(=O)NCC2CCCO2)c1C +Cc1oc(C(C)C)cc1C(=O)N1CCC(Cn2cc(CO)nn2)CC1 +COc1ccc(C(O)C(C)NC(=O)c2ccc(N(C)C)nc2)cc1 +COCCOc1cccc(CNC(=O)C2CC3CCC2O3)c1 +Cc1cc(C(O)CN(C)c2ccccc2)ccc1F +CC(=O)Nc1cc(C(=O)Nc2cc(Cl)cc(Cl)c2)ccc1F +CC1(c2nc(CCc3ccccc3)nn2CC(F)(F)F)CCCO1 +Cc1cc(C(=O)N2CCC(O)(C(F)(F)F)CC2)c(C)n1C(C)C +O=C(Cc1ccc(F)cc1)N1CCc2ncccc2C1 +COC(=O)C(NC(=O)CSc1ccccc1C)C(C)C +CC=Cc1cc(C(=O)NC(C)c2ccncc2)cc(OC)c1OC +COc1ccc(Cl)cc1NC(=O)CNc1ccn(CC(N)=O)n1 +COc1ccccc1CC1CCCN(C(=O)c2cn[nH]c2C)C1 +CC(C)CCN(C)C(=O)c1cc2ccccc2oc1=O +CC(C)c1ccc(OCC(=O)N2CCOCC2)cc1 +CC(C)CC(=O)Nn1cnc2c(cnn2-c2cccc(Cl)c2)c1=O +COc1cccc(C(=O)NCC(=O)Nc2ccc(OC)c(Cl)c2)c1 +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1nc(-c2cccnc2)cs1 +Cc1cc(C)c(S(=O)(=O)N(C)CC(=O)NC2CC2)c(C)c1 +CN(Cc1cnc2ncccn12)CC1CCCCO1 +CCC(C1C(=O)CC(C)(C)CC1=O)C1C(=O)CC(C)(C)CC1=O +Cc1ccc(OC2CCN(C(=O)C3CC3)CC2)cc1 +CC(=Cc1ccco1)C1CC(=O)Nc2nn3c(C)cc(C)nc3c21 +COc1c(N)cc(-c2nc3cnccc3o2)cc1N +CCc1onc(C)c1NC(=O)c1cc(-c2ccccc2)no1 +CCC(C(=O)Nc1cccc(N)c1)n1cc(Cl)ccc1=O +c1cc(-n2cnnn2)ccc1OCc1nc(C2CC2)n[nH]1 +Cc1ccc(OCC#CCNC(=O)c2c(F)cccc2Cl)cn1 +Cn1ccc(NS(=O)(=O)c2ccc3c(c2)S(=O)(=O)N=CN3)n1 +Cn1nnnc1SCCC(=O)Nc1cccc(F)c1F +COCc1cc(C(=O)Nc2ccc(Br)cn2)ccc1F +COCC(C)NC(=O)Nc1ccc(OC(C)C)c(Cl)c1 +Cc1c[nH]nc1C1CCCN(C(=O)c2cccc(Cl)c2)C1 +CCCn1c(N)c(C(=O)CSc2ncn[nH]2)c(=O)n(C)c1=O +CCCC(=O)N1CCC(C(=O)Nc2cc(C)cc3cccnc23)CC1 +Cc1cc(C(=O)NCC(=O)Nc2ccc3c(c2)CCC(=O)N3)c(C)o1 +CC(OCc1ccco1)C(=O)Nc1ccc(N)cc1Cl +NC(=O)C1COCCN1c1cnc2cc(F)c(F)cc2n1 +CN(C)C(=O)c1ccc(NC(=O)Cc2ccc3c(c2)CCCC3)cc1 +Cc1cc(C)c(S(=O)(=O)NCc2cn3ccccc3n2)cc1C +Cn1cc(S(=O)(=O)NC2CCCCNC2=O)cn1 +Cc1cc(O)nc(-n2[nH]c(=O)c3nccnc3c2=O)n1 +CCCNS(=O)(=O)c1ccc(C)c(C(=O)NC2CCCCC2)c1 +CC(C)(C)NC(=O)N1CCN(Cc2cc3ccccn3n2)CC1 +CCCN(C)C(=O)Nc1nnc(C(F)(F)F)s1 +C#CCNC(=O)c1cc(S(=O)(=O)NCc2ccco2)ccc1C +Cc1nn(C)c(C)c1-c1ccnc(NCc2cccc3[nH]ccc23)n1 +Oc1ccc2c(c1)ncn2Cc1ccc(C(F)(F)F)cc1 +CCCNC(=O)Nc1ccc(S(=O)(=O)NCC(F)(F)F)cc1 +O=c1onc(-c2cccc(C(F)(F)F)c2)n1-c1ccccc1 +O=c1nc(NCCCN2CCOCC2)[nH]nc1-c1ccc(F)cc1 +Cc1c(C(=O)C(C#N)c2nnc3n2CCCCC3)oc2c(C)cccc12 +C#CCCN1CCN(C(=O)Nc2ccccc2)CC1 +NC(=O)c1ccc(OCC(=O)Nc2c[nH]ccc2=O)cc1 +CCCn1c(NS(=O)(=O)c2cccs2)nc2ccccc21 +COCC(C)NC(=O)N1CCN(C(=O)c2cccc(O)c2)CC1 +COc1ccc(CCc2nnc(C(C)C)o2)cc1N +CC(C)C(NC(=O)N1CCCCC1C)c1nnc2n1CCC2 +COc1ccc(C(=O)N2CCC(C#N)CC2)cc1OC +CCc1cccc(OCc2nc(C(=O)N3CCOCC3)cs2)c1 +Cc1csc(C2CN(CC(=O)NCc3cccs3)CCO2)n1 +CCCCNC(=O)N1CCC2(CC1)COCCN(c1ncccn1)C2 +CN(C(=O)Cn1nc(-c2cccnc2)oc1=O)C1CCCCC1 +COC(=O)c1cc2c(nc1NC(=O)c1occc1C)CCCC2 +CCc1ccc(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)cc1 +CC(C)c1nc(NC(=O)c2cn(C)nc2-c2cccs2)n(C)n1 +O=C(Nc1ccc(N2CCCC2)nc1)c1ccccc1-n1cccn1 +Cc1ccc(-c2ncc(CN3CCN(S(N)(=O)=O)CC3)s2)o1 +COc1cccc(C(=O)NCCO)c1OC(F)F +Cc1ccc(NC(=O)c2cccnc2OCC(F)F)cn1 +CC(=O)NCCc1cn(C(=O)OC(C)(C)C)c2ccc(O)cc12 +CCc1cnccc1C(=O)Nc1cc2c(cc1F)NC(=O)CC2 +CCOc1ccccc1NC(=O)CCNC(=O)c1cccc(C)c1 +N#CC(NS(=O)(=O)CCCc1ccccc1)c1ccco1 +Cn1cc(C2CC(=O)NC23CCN(C(=O)C2CC=CC2)CC3)cn1 +CCOCC(=O)Nc1ccccc1COc1ccccc1 +COCCN(C)C(=O)Nc1ccc(F)c(NC(=O)c2ccoc2C)c1 +CS(=O)(=O)N(CCCO)c1cc(Cl)ccc1Cl +COCCn1c(C)cc(-c2ccccc2)c(C#N)c1=O +COc1cc(F)c2c(c1)C(c1ncccc1Cl)NCC2 +COCCCNC(=O)CN1CCN(c2ccc3c(c2)OCCO3)C1=O +CCn1nc(C)cc1C(=O)Nc1c2c(nn1-c1ccccc1)CCC2 +NC(=O)CCNC(=O)C1COC(=O)N1Cc1cnc[nH]1 +O=C(CSc1nnc(Cn2cncn2)o1)N1CCc2ccccc21 +COCc1ccccc1NCc1ccc(OC)c(OC)c1 +Cc1ccc(-n2ccnc2SCCC(N)=O)cc1C +COC(=O)CCC(=O)Nc1cccc(-n2nc(C)cc2C)c1 +O=C(CCc1cccc(Br)c1)OCc1ccccn1 +Cc1ccc(C)c(CSc2nnc(-c3cnccn3)n2C)c1 +CCC1CCC(CNC(=O)CCc2c(C)nc3ncnn3c2C)CC1 +Cc1ccc2ncc(C(=O)N3CCN(c4ccccc4O)CC3)n2c1 +COC(=O)C(C)(C)NC(=O)CSc1nccn1C +COCC(NC(=O)C(C)Oc1ccccc1Br)C(N)=O +CC(Oc1cccc(Cl)c1)C(=O)N1CCCC1 +COc1cc(C)c(C(=O)NCCCO)cc1OC +Cc1ccc(C(=O)NCCC2CNc3ccccc32)cc1 +Cc1cc2c(=O)n(Cc3cnn(C)c3C(F)(F)F)cnc2s1 +COC(=O)C1CC(Oc2ccccc2C(C)=O)CN1 +NC(=O)C(NC(=O)NCc1ccc2c(c1)CCC2)c1ccccc1 +CCC1CCCN(C(=O)c2cc3ccccc3oc2=O)C1 +COc1ccc(CN(CC(C)C)C(C)=O)cc1OS(C)(=O)=O +COCC(=O)N1CCN(c2ccc(-n3cccc3)nn2)CC1 +CNC(=O)NCC(=O)Nc1ccc(Br)c(OC)c1 +O=C(Nc1cccnc1)N1CCCC1c1ccsc1 +O=C1COc2ccc(NC(=O)c3ccc(-n4ccnc4)nc3)cc2N1 +CCOc1ccccc1NCc1ccc(OC)c(O)c1 +COc1cccc2c1cc(C(=O)N1CCCCCC1)n2C +CC(C)c1nccc(NCC(O)COc2ccc3c(c2)OCO3)n1 +NC(=O)N1CCc2cc(NC(=O)c3cccc(-c4ccoc4)c3)ccc21 +CN(C)S(=O)(=O)N1CCCC(C(=O)NCc2ccncc2)C1 +O=C(NCCO)NCCS(=O)(=O)c1ccc(Cl)cc1 +CCCCN(C)C(=O)CSc1cc(C)nc(C)c1C#N +COc1ccc(OC)c(C(C#N)NCc2ccc(C)cc2)c1 +Cc1nccn1-c1ccc(NC(=O)c2ccccc2-n2cnnn2)cn1 +CN(Cc1ccccc1)C(=O)Nc1ccc(-n2cnnn2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)NCC(C)Cn1cccn1 +Cc1ccc(CNC(=O)c2cc(=O)[nH]c3ccccc23)cc1 +COc1ccc(-c2cn3c(nc4cc(N)ccc43)[nH]2)c(C)c1C +CC(NC(=O)c1cccc(-n2cccn2)n1)c1ccc(Cl)cc1 +COc1ccc(OCC2CN(Cc3cccs3)CCO2)cc1 +CCCN(CCC)S(=O)(=O)c1cccc(C(C)=O)c1 +Cc1cnc(C(=O)OCC(=O)NCCC2=CCCCC2)cn1 +COC(=O)CCCN1CCOc2cccc(N)c21 +CC(C)C(NC(=O)Cc1cccc(OCC#N)c1)C(N)=O +Cc1cnc(C)c(N2CCN(c3ccc(C(N)=O)cn3)CC2)n1 +CCn1c(=O)n(CCC(=O)N(C)Cc2ccco2)c2ccccc21 +COCc1cc(=O)[nH]c2cc(NC(=O)c3cn(C)nn3)ccc12 +OCc1nnn(-c2ccccc2)c1-c1ccc2c(c1)OCO2 +CCc1nnc(NC(=O)c2csc(C)n2)s1 +CN(Cc1ccncc1)C(=O)NC(c1ccccc1)C1CCC1 +COc1ccc(NC(=O)NCC(C)(O)C2CC2)cc1 +O=C(NCc1ccccn1)Nc1ccc(Oc2ncccn2)cc1 +COc1cccc(NC(=O)c2ccc3snnc3c2)c1 +Cc1nc(C(=O)Oc2ccc3c(c2)OCO3)nn1-c1ccc(F)cc1 +COC(=O)CN1C(=O)CNc2cc(Br)ccc21 +COc1ccccc1C(NC(=O)C1CC(=O)N(C)C1)C(C)(C)C +CS(=O)(=O)NCCNc1ccc(-n2cccn2)nn1 +COc1ccc(C)cc1NCC(O)c1ccc(F)c(N)c1 +O=C(COc1ccc2c(c1)CCC2)N1CCC(O)(C(F)(F)F)CC1 +O=C(NCC1(C2CC2)CCC1)c1ccc(OCC(F)F)nc1 +Cc1cc(C)cc(-n2nnc(C(=O)Nc3ccccc3)c2N)c1 +O=C(NCc1ccc(O)cc1)N1CCC2(CC1)OCCO2 +COc1cccc(C(=O)NC2CCCCC2n2cccn2)c1F +CCc1cccc(C)c1NC(=O)C(C)NC(=O)c1ccco1 +CC1CCCC(C)N1C(=O)N1CCC(c2nnc3ccccn23)CC1 +Cc1nn(-c2ccc(Cl)cc2)c2sc(C(N)=O)cc12 +Cc1cccc(NC(=O)CCNC(=O)CNC(=O)c2ccoc2C)n1 +Oc1ccc2c3c(ccc2c1)CCNC3c1cc[nH]n1 +O=S(=O)(c1ccc(SCc2cccnc2)nc1)N1CCCCC1 +CCn1ncnc1-c1nccn1Cc1cnn(-c2ccccc2OC)c1 +CNC(=O)c1cccc(NC(=O)c2ccc3ccccc3n2)c1 +COc1ccc(C=C2OC(=O)c3c(OC)cccc32)cc1O +Cc1cc(Cl)ccc1S(=O)(=O)NC1CCC(O)CC1 +CCOc1ccc(NC(=O)NCCNC(C)=O)cc1F +O=C(CN1CC2(CCOCC2)Oc2ccccc2C1=O)NC1CC1 +CC(C)(C)c1cnc(CNC(=O)Cc2ccc[nH]2)o1 +COCCC(=O)N1CCC(O)(c2cccc(C(F)(F)F)c2)CC1 +CCOC(=O)CN(C(=O)c1cc(C)oc1C)C1CC1 +COc1cc(-n2nnc(C(=O)NC(C)C)c2N)ccc1Cl +CC(=O)NCCCOC(=O)c1cn(C)nc1-c1cccs1 +CC(=O)c1ccc(S(=O)(=O)NCCC(=O)N2CCCC2)cc1 +Cc1ccoc1C(=O)N1c2ccccc2CC1C(N)=O +Cn1nnnc1SCC(=O)N1CCCCCC1 +Nc1cc(F)cc2c(C(=O)N3CCc4ccccc43)nccc12 +Cc1nc(C(C)C)ncc1C(=O)NCc1nc2c(C)cccc2[nH]1 +Cc1noc(C)c1CN(C)C(=O)c1c(C)nn(C)c1C +Cc1ccccc1S(=O)(=O)NCCNC(=O)N1CCCCC1 +O=C(CCOCC(F)(F)F)NCc1cscn1 +O=C(NCC(=O)N1CCCC1)c1c[nH]nc1-c1ccccc1F +CC1CN(c2cnn(-c3ccccc3)c(=O)c2Cl)CC(C)(C)O1 +O=C(NCCNC(=O)c1n[nH]c(=O)[nH]1)c1ccc(Cl)cc1 +O=C(CNC(=O)c1ccc(F)c(F)c1)Nc1ccnc2ccnn12 +CC(NC(=O)NCC(=O)NC1CC1)c1ccccc1Br +CC(=O)C(C)CSc1nnc(-c2ccco2)n1CC(C)C +COc1cc(Nc2ncccc2C(N)=O)c(OC)cc1Cl +CC(C)Cn1cc(NC(=O)NCC(C)(O)c2ccsc2)cn1 +Cc1ccccc1C1(CNC(=O)CSc2nnnn2C2CC2)CC1 +CCc1onc(C)c1NC(=O)c1cc(C(C)(C)C)on1 +O=C(NC1Nc2ccccc2S1)c1ccc2[nH]nnc2c1 +CC(C)(C)n1ccnc(NCCC(F)(F)F)c1=O +COc1ccc(C)cc1NC(C)c1nc(-c2ccco2)no1 +COC(=O)CCNC(=O)c1csc(-c2cccc(Cl)c2)n1 +COC(=O)C1=C(N)Oc2[nH]nc(C)c2C1c1ccccc1 +Cc1cccc(OCC(=O)Nc2ccccn2)c1C +CC(NC(=O)CCc1ccc2c(c1)OCO2)c1cccnc1 +Cc1cc(C)c(CC(=O)N2CCC(=O)CC2)c(C)c1 +Cc1ccc(F)cc1C(=O)N1CC(=O)Nc2ccccc21 +CC(NC(=O)c1cn[nH]c1)c1c(F)cccc1F +Cc1cccc(-c2nc(N)nc3c2CN(C(=O)c2cc(C)n[nH]2)C3C)c1 +Nc1cccc(C(=O)CCC(=O)NCc2cccnc2)c1 +CCN1C(=O)C(C)(C(=O)NCC(=O)N(C)C)Sc2ccccc21 +CCN(Cc1nc(C)cs1)Cc1ccccc1Cl +CCn1cnnc1C1CCN(C(=O)c2ccc3ccccc3n2)CC1 +COCC(NC(=O)CC=Cc1ccc(C)cc1)C(N)=O +O=C(Nc1nnc2ccccn12)c1cnc2ccccn2c1=O +CC1CCC(N2CC(C(=O)NC3C4CCOC4C3(C)C)CC2=O)CC1 +CCn1nnc2c(SCc3ccccc3F)ncnc21 +CC1CCCCN1C(=O)CNc1ccc(F)c(Cl)c1 +Cc1ccc(C)c(-c2cn(-c3cccc(N)c3)nn2)c1 +O=C(c1cccs1)N1CCC2C1CCN2c1ncccn1 +CCOc1cc(C(=O)Nc2cnn(-c3ccccc3F)c2)ccn1 +NC(=O)CN(C(=O)C1CCCc2ccccc21)C1CCCC1 +CCOc1cc(CNc2ccc3nnnn3n2)ccc1OC(F)F +COc1ccc(CNC(=O)CCc2ccccn2)cn1 +CC(=O)N1CCC(NC(=O)COc2ccc(-n3cnnn3)cc2)CC1 +COCC(C)(O)CNC(=O)NCc1ccc(OC)cc1 +CCc1cc(C(=O)C(C#N)c2nnc3n2CCCCC3)sc1C +CCCC(C)C(=O)N1CCN(C(=O)Cc2cccc(OC)c2)CC1 +Fc1c(Cl)ccc2c1CCNC2c1cncs1 +COc1cc(NC(=O)NCCC2CC3CCC2C3)cc(OC)c1OC +Cn1cccc1C(=O)N1Cc2nccn2CC(CN2CCOCC2)C1 +Cc1cccc2cnn(CCC(=O)NCC(C)C)c12 +CCn1ccc2c(OCC(=O)NCC3CCCO3)cccc2c1=O +Cc1ccc2c(=O)n(CCC3CCCCO3)cnc2c1 +COc1ccc(S(=O)(=O)Nc2ccccc2C)cc1NC(C)=O +CC(Sc1nnnn1C)C(=O)Nc1ccc(Cl)c(Cl)c1 +COc1ccc(C2(CNS(=O)(=O)c3cccnc3)CCCC2)cc1 +CCOC(=O)c1cccc(NS(C)(=O)=O)c1C +Cc1nnc(CSc2nnc(N3CCOCC3)n2CC(C)C)o1 +N#Cc1ccc(Oc2ccc(NC(=O)NCCCO)cc2Cl)cc1 +c1cnn(CC2CCCCN2c2ncnc3sccc23)c1 +N#Cc1cccc(C(=O)NCCc2ccccc2Cl)c1 +Cc1cc(NC(=O)C2CC=CC2)ccc1OC1CCOCC1 +COc1ccccc1-c1nc2sc(C)cn2c1N +COc1ccc(OCC(=O)N(CCC#N)c2ccccc2F)cc1 +CC1CCCCN1C(=O)CN1CCN(c2ccc3nncn3n2)CC1 +CCOC(=O)Cc1nc2ccc(Br)cc2s1 +CNc1cc(Br)c(Br)cc1OC +CCn1nnc2cc(C(=O)Nc3ccc(C#N)c(Cl)c3)ccc21 +CCC(NC(=O)NCCC(=O)NC(C)C)c1cccs1 +CC(C)NC(C#N)CCN1CCN(S(C)(=O)=O)CC1 +CCN1C(=O)C(C)(C(=O)Nc2cnn(C(C)C)c2)Oc2ccccc21 +Nc1ccc2c(NC3CCN(c4cccc(F)c4)CC3)ncnc2n1 +Cc1cc(OCCCc2nc(CO)cs2)ccc1Cl +CCCCc1nnc(NC(=O)c2ccc(=O)n(CCC)n2)s1 +CN(CCO)C(=O)c1sccc1-n1cnnn1 +CC(C)CCOC(=O)C(C)n1c(=O)oc2cccc(N)c21 +Cc1csc(CNC(=O)Nc2ncccc2C)n1 +C=CCNC(=O)Nc1cccc(OCC(=O)N(C)C)c1 +COc1ccccc1NCc1cccc2cccnc12 +O=C(COc1cccc2cccnc12)NCCc1ccccc1 +CN(Cc1ccc(O)cc1)C(=O)c1ccc[nH]c1=O +CCCN(CCC)C(=O)C1CN(c2ncnc3c2nnn3C)C1 +O=C(CCC(=O)N1CCOCC1)Nc1cnn(Cc2ccccc2)c1 +CC(C)c1cc(C(=O)Nc2c[nH]cc(Br)c2=O)n(C)n1 +C=CCCCN(C)C(=O)Cc1csc(C(C)(C)C)n1 +CC(C)n1cnnc1SCc1nc(CCc2ccccc2)no1 +Cc1ccc(N2CC(C(=O)NC(C)Cn3cccn3)CC2=O)cc1F +O=C(NCCn1ccnc1-c1ncccn1)C1CC=CCC1 +CC(NC(=O)NC1CCSc2ccccc21)c1nncn1C +CCC(NC(=O)NCC(O)Cc1ccccc1)c1cc(F)ccc1F +CCCc1ccc(S(=O)(=O)NC2CCC(c3ncno3)CC2)cc1 +COCCCNC(=O)NC1CCc2cc(Cl)ccc21 +N#Cc1ccc(-c2noc(-c3ccc(Cn4ccnc4)cc3)n2)nc1 +O=C(CCn1ccccc1=O)Nc1cc(F)cc(F)c1 +CCCOc1cc(C)ccc1NC(=O)NCc1cccc(C(N)=O)c1 +CCNC(=O)CN(CC)C(=O)C(C)Sc1nncs1 +CC(C)CCNC(=O)c1cc(=O)c2cc(Cl)cc(N)c2o1 +CCc1cc(=O)[nH]c(CN2CCc3nn(C)c(=O)cc3C2)n1 +CCC(=O)N1CCC(c2ncc(C(=O)Nc3ccccc3)c(C)n2)C1 +COc1ccc(CNc2ccn3nc(N)nc3c2)cc1 +O=C(c1c[nH]c2ccccc2c1=O)N1CCC(c2ccc(O)cc2)CC1 +CC(C)S(=O)(=O)N1CCC2(CC1)CNC(=O)c1ccccc1O2 +CN(C(=O)c1ccnc(OC2CCC2)c1)c1nccs1 +COC(=O)CCNC(=O)COc1ccc2c(C)cc(=O)oc2c1 +CC(NC(=O)CNC(=O)C1CCCC1)C(=O)N1CCCCC1 +CCN(CC(F)(F)F)C(=O)c1cc(F)cc(Br)c1 +CCCC(=O)Nc1ccc(CNC(=O)NCc2ccccn2)cc1 +Cc1cc(NC(=O)c2cc3ccccc3o2)n(C)n1 +CC(=O)N1CCN(C(=O)c2ccc(-n3cnnn3)cc2)CC1 +CCc1ccc(C(=O)Nc2nc3ccc(NC(C)=O)cc3s2)cc1 +CCOc1ccc(-c2noc(CSc3nncn3C)n2)cc1 +Cc1csc(NC(=O)c2c(C)nn(-c3ccccc3)c2C)n1 +Cc1cc(C)c(CNS(=O)(=O)N(C)CCC#N)c(C)c1 +N#Cc1ccc(CNC(=O)c2ccnc(F)c2)cc1 +CCCCC(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +Cn1c(=O)c(C(=O)N2CCCCCC2)nn(-c2ccccc2)c1=O +CS(=O)(=O)N1CC2CC(C(=O)Nc3ccccc3)C(C1)O2 +Nc1c(-c2ccccn2)nc2cc(Br)ccn12 +C=CCN(CC=C)C(=O)NC1CCN(C(=O)OC)CC1 +N#CCSc1nnc2c(S(=O)(=O)N3CCCCC3)cccn12 +Cc1nc(-c2ccc(C)c(S(=O)(=O)NC3CCCC3)c2)cs1 +CCOC(=O)C(C)(C)N1C(=O)CNc2cc(C)c(C)cc21 +COCC1CN(C(=O)NC(Cc2ccc(F)cc2)C(C)C)CCO1 +Cc1oc(C2CCN(C(=O)C3CCCO3)CC2)nc1C(=O)N(C)C +CC(C)Nc1cccc(CNC(=O)NCC(C)N2CCOCC2)c1 +O=C(Nc1nc2c(c(=O)[nH]1)CCCC2)c1ccc(Cl)cc1 +O=S(=O)(c1ccc(F)c(F)c1)N1CCN(Cc2ccco2)CC1 +CCCc1noc(CCC(=O)N(C)Cc2ccccc2)n1 +CCN(CC)S(=O)(=O)c1ccc(C(=O)NC(C)(C)CC)cc1 +CN(C(=O)CCSc1ccccc1)c1cccc2ncccc12 +COCc1ccccc1NCC(=O)Nc1cc(C)on1 +Cc1ccccc1-c1cnc(NC(=O)NCc2cnn(C)c2C)s1 +Cc1ccc(-c2ccnc(NC(C)Cc3cccnc3)n2)c(C)n1 +Cc1ccc(OCC(=O)NCc2ccccc2)cc1C +Cc1ccc(-c2noc(CN(C)C(=O)c3ccccc3)n2)cc1 +Cc1ccc(C)c(OCc2n[nH]c(CC(=O)NC3CCCC3)n2)c1 +Cc1[nH]ncc1S(=O)(=O)NC(C)c1ccccn1 +CNC(=O)c1cccc(NC(=O)CCCc2cccs2)c1 +Cc1ccccc1C(=O)Nc1cccc(C(=O)NCc2ccco2)c1 +Cc1c(C(=O)NC2CCCCC2C(C)(C)C)cnn1C +Cc1c(C(=O)N2CC(CO)OCC2C)c(=O)[nH]c2ccccc12 +O=C(NCC1CN2CCCC2CO1)Nc1cccnc1 +N#Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)c(F)c1 +CCOCC(=O)N1CCc2cc(S(=O)(=O)N(CC)CC)ccc21 +Cn1nc(C2CCC2)cc1NC(=O)NC1CC2CCC1O2 +CC(C)C(CCNC(=O)C1CCOC(C)(C)C1)c1ccco1 +CCC(=O)N1CCc2ccc(NC(=O)c3cc(C)on3)cc2C1 +COc1ccc(C(=O)Nc2cccc(NC(C)=O)c2)nn1 +O=c1ccc(-c2ccccc2)nn1Cc1noc(C2CC2)n1 +Cc1cccc(CCc2nn3cc(N)nc3s2)c1 +Cc1cc(Cl)ccc1OCCCC(=O)NCc1ccccn1 +CC(C)c1noc(C(C)Sc2n[nH]c(N)n2)n1 +CCNC(=O)c1cc(-c2ccccc2)nc2c(C(N)=O)ncn12 +CCOc1ncccc1CNC(=O)c1ccc(CNC(N)=O)cc1 +Cc1nc2c(s1)C(NC1CCN(c3ncccc3F)C1)CCC2 +O=C(CSc1ccncc1)Nc1ccnn1C1CCCCC1 +CCOc1ccccc1CCC(=O)N(C)c1ccc(Cl)cn1 +C=CCOC(C)C(=O)Nc1ccc2nccnc2c1 +COCCCN1CC2(CCCN(c3nccnc3OC)C2)CCC1=O +Cc1ccc2c(c1)C=Cc1ccccc1N2C(N)=O +O=C(CNc1cnc2sccn2c1=O)NCCN1CCOCC1 +COCc1ccc(C(=O)N(C(C)C)C2CCC2)cc1 +C=CCNC(=O)CNC(=O)c1ccc(C(C)(C)C)cc1 +Cc1ccccc1NC(=O)C(C)Sc1nnc(N)[nH]1 +C#CCN(CC(=O)NCC1CCC1)C1CCc2ccccc21 +CS(=O)(=O)N1CCCC1c1n[nH]cc1-c1ccccc1F +Cc1cc(NC(=O)Nc2cccc(COC(C)C)c2)no1 +CC(Cc1ccccc1F)Nc1ncnc2[nH]cnc12 +CCOC(=O)c1sc(NC(=O)Cc2cccs2)cc1C +CN1CC(c2nc(-c3ccc(OCc4ccccc4)cc3)no2)CC1=O +Nc1ccc(-n2cc(-c3cccnc3)nn2)c(Cl)c1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cccc(Cl)c1Cl +CNC(=O)CCN1CCOC(c2ccc3cc(OC)ccc3c2)C1 +O=C(CNC(=O)c1cc(F)cc(F)c1)NCc1cccs1 +C=CCNC(=O)CSc1nc(-c2ccc(CC)cc2)n[nH]1 +O=C(NCc1csc(N2CCCC2)n1)c1ccn2nnnc2c1 +Cc1nc(C(C)(C)NS(=O)(=O)c2cccc(F)c2)sc1C +O=C(Cn1c(=O)c(=O)n(Cc2ccccc2)c2ccccc21)NC1CC1 +COc1ccc(S(=O)(=O)N(C)C)cc1C(N)=O +O=C(Nc1ccccc1Br)C1CCN(CC(F)F)CC1 +NC(=O)C1CCN(c2ncc(Br)cn2)C1 +O=C(Cn1c(C2CCCCC2)nc2ccccc21)NCC1CCCO1 +O=c1[nH]c(CNc2ccccc2)nn1Cc1cccc(C(F)(F)F)c1 +CCC(=O)Oc1cccc(C(=O)NCC2CCCO2)c1 +CCS(=O)(=O)c1ccc(C(=O)NCCOC)cc1 +Cc1cccc(OC(C)C(=O)Nc2sc(C)c(C)c2C(N)=O)c1 +O=S(=O)(Nc1ccc(Br)cc1F)c1cccnc1 +O=C(NCc1cccnc1)NCc1ccccc1OCC(F)(F)F +CN(C)C(=O)N1CCN(Cc2coc(-c3ccc(Cl)cc3)n2)CC1 +COC(=O)C1CC(O)CN1Cc1cccc(-c2ccccc2C)c1 +Cc1nn(CC(=O)NC2CCCC(C)C2C)c2ccccc12 +CC(C)c1nnc2sc(Cc3ccccc3N)nn12 +O=C(Cc1cccc(Br)c1)N1CCCC1 +CCn1nc(C(=O)Nc2cccnc2)cc1-c1cccc(OC)c1 +O=C(NCc1cccc(C(F)(F)F)c1)c1ccccc1 +CN(CC1CCCO1)C(=O)CNC(=O)c1cc2c(s1)CCCC2 +CCS(=O)(=O)c1ccc(C(=O)N=c2[nH]c3ccccc3[nH]2)cc1 +c1ccc2oc(-c3noc(-c4ccon4)n3)cc2c1 +Cc1n[nH]c(C2CN(C(=O)CCC3CCCCO3)CCO2)n1 +CCOc1c(Cl)cc(CNC(=O)NCc2ccccn2)cc1OC +Cc1cc(C)n(-c2ccc(C(=O)N(C)C(C)c3cncs3)cc2)n1 +CC(C(=O)Nc1ccc(OCC(N)=O)cc1)c1cccs1 +Cc1ccc(C(=O)OCC(=O)NCc2ccccc2)s1 +O=C1CNc2ccccc2N1Cc1ccccc1Cl +CN(C)S(=O)(=O)N1CCCC(C(=O)NCC2CCCCC2)C1 +Cc1c(C(=O)NC2CCOc3ccccc32)oc2c1C(=O)CCC2 +O=C(CS(=O)(=O)c1ccccc1F)Nc1cccc(F)c1 +CC(C)Oc1ccc(NC(=O)c2cc3cccnn3c2)cc1 +Cc1cc(C(=O)N2CCN(C(=O)c3ccoc3)CC2)c(C)s1 +CC(Sc1nc2ncccn2n1)C(=O)N1c2ccccc2CC1C +CCOCc1ccccc1NC(=O)NCCN1CCOCC1 +COc1ccc(C(=O)N2CCCC2)cc1NC(C)=O +O=C(NC1(c2cccc(Cl)c2)CC1)C1CC=CC1 +CCc1nnc2n1CCN(C(=O)COCCOc1ccccc1)C2 +COc1cc(C)c(S(=O)(=O)N(C)CC(N)=O)cc1C +CC1Cc2ccccc2N1c1nc(N)c2c(n1)CC(C)(C)CC2=O +CC(C)(C)CCC(=O)Nc1ccc(N2CCNC(=O)C2)nc1 +CCCCCSc1nc2ccccc2n1CC(N)=O +CC(Sc1ccccn1)C(=O)Nc1ncnc2nc[nH]c12 +O=C(NCc1cccs1)C12CC3CC(CC(O)(C3)C1)C2 +O=C(COc1ccccc1CO)NCCc1ccc(F)cc1 +CC(NC(=O)CSc1ccccn1)c1ccccc1 +Cc1ccc(CN2CCc3c(nnn3C)C2COCC2CC2)o1 +O=C(CO)N1CCN(CC(=O)N2CCc3ccccc3C2)CC1 +COc1cc(CNC(=O)c2cc3ccccc3[nH]2)ccn1 +COc1ccc(N)cc1NC(=O)Nc1ccc(C#N)cc1 +Cc1ccc(F)cc1S(=O)(=O)Oc1ccccc1 +O=C(NCC1(O)CCCc2ccccc21)c1cccc2c1OCCO2 +CC(C)c1cc(C(=O)NCc2noc(Cc3ccccc3)n2)n(C)n1 +CCc1c(C(=O)Nc2cc(OC)ccc2F)[nH]c(C)c1C(C)=O +C=CCNC(=O)NC(C)c1ccc(OC2CCCC2)c(OC)c1 +COC(=O)CC1Nc2cc(Br)ccc2NC1=O +Cc1csc(C2CCCN(C(=O)c3ccc(N(C)C)nn3)C2)n1 +COc1ccccc1C(=O)c1ccc(OCC#N)cc1 +CCCC(C)N1CC(c2nc(-c3ccc(C#N)cn3)no2)CC1=O +CC(C)(C)OC(=O)N1CCCC(Oc2ccc3[nH]ncc3c2)C1 +Cc1cc2ncc3c(n2n1)CC1CCC3N1Cc1ccco1 +N#Cc1cc2cc3c(cc2nc1N1CCCCC1)CCCN3 +CC(=O)c1ccc(C(=O)NCC(C)(C)N2CC(C)OC(C)C2)s1 +C#CCNC(=O)C(C)Nc1ccc(C#N)c(Cl)c1 +N#CCCN(CCC#N)C(=O)CNc1cccc(Br)c1 +CCc1nc(CN2CCc3cc(F)ccc3C2)cs1 +Cc1nn(Cc2ccccc2)c(C)c1C(=O)NCc1ccc(F)cc1 +CC(C)CNC(=O)C1(NCc2cc(F)ccc2F)CCCC1 +CC(C)NC(=O)N(CCCN1CCOCC1)Cc1ccncc1 +O=C(c1cc(Cl)c2c(c1)OCCO2)N1CCc2ccccc2C1 +Cc1c(C(=O)OCC(=O)N2CCCC(C)C2)oc2ccccc12 +Cc1occc1CN(C)C(=O)c1cc2ccccc2c(=O)[nH]1 +CC(C)(C)C(=O)N1CCCC1Cn1nnc(-c2cccs2)n1 +O=c1c2ccsc2ncn1Cc1coc(-c2cccs2)n1 +Cc1cc(Br)c(Br)cc1N +O=C(NC(c1cccc(Cl)c1)c1ccccn1)c1cc[nH]n1 +CC(C)C(=O)NCC1CCN(C(=O)c2cccnc2)CC1 +Cn1cc(CNC(=O)N2CCCN(C(=O)c3ccccc3)CC2)cn1 +CCOc1ccc(NC(=O)c2cc3ccc(OC)cc3oc2=O)cc1 +Cc1sc2ccccc2c1S(=O)(=O)N(C)Cc1ccccn1 +CCc1n[nH]c(SCC(=O)NC(C(C)=O)C(C)C)n1 +CC(C)(C)C(=O)N1CCC(NC(=O)Nc2ccc(F)cc2)C1 +CCOc1ccc(F)c(C(=O)NCc2cccc(C#N)c2)c1F +Cc1cc(C(=O)N2CCC(Oc3nc4ccccc4s3)CC2)no1 +CCN(Cc1ccccc1NC(=O)NCc1ccco1)C(C)=O +Cc1ccc(NC(=O)N2CCN(Cc3ccncc3)CC2)c(Cl)c1 +NS(=O)(=O)c1ccc(CNC(=O)Nc2c(F)cccc2F)cc1 +Cc1noc(C)c1CN1CCN(Cc2cnc(C(C)C)s2)CC1 +O=c1[nH]n(C2CCCCC2)c2c1C(c1cccc(O)c1)CC(O)=N2 +O=C(Nc1ccccc1O)c1cccc(-n2cnnn2)c1 +CC1c2ccsc2CCN1C(=O)Nc1cccc(-c2nnco2)c1 +Cc1ccccc1N1CCN(C(=O)CNC(=O)c2ccsc2)CC1 +Cc1ccc(OC2CCN(C(=O)c3c(F)cccc3F)CC2)cn1 +CCCCNC(=O)c1ccc(NCC(=O)N2CCC(C)CC2)cc1 +COc1ncc(C(=O)NCc2ccc(C(C)C)cc2)cn1 +Cc1csc(NC(=O)c2nnn(-c3ccc(F)cc3)c2C2CC2)n1 +NC(=O)NCC(=O)NCc1ccc(Br)cc1Cl +CN(C(=O)CNc1ccc(Cl)cc1C(N)=O)c1ccccc1 +CCc1ccc(C(O)CNC(=O)C2CCCCC2)cc1 +Cc1ccccc1C(C)NC(=O)N1CCN(C(=O)N(C)C)CC1 +Cc1nc(CC(=O)N(Cc2ccncc2)Cc2cccnc2)cs1 +CCOc1ccc(C(=O)NC(C)C(=O)Nc2ccccc2)cc1 +CC1(C)Cc2cccc(OCCNS(=O)(=O)c3ccccc3)c2O1 +CC(=O)Nc1cc(NCc2ccc(F)cc2)ccc1F +CC(=O)Nc1ccc(CC(=O)Nc2ccc3nc(C)oc3c2)cc1 +CCOc1ccccc1C(C#N)N(C)C(=O)OC(C)(C)C +CN(Cc1cscn1)C(=O)C1(c2ccc(F)cc2)CCC1 +CN(CCC#N)C(=O)Nc1ccc(Oc2ccc(F)cc2F)nc1 +Cn1c(SCc2ccc3ccccc3n2)nnc1-c1ccco1 +CCc1nc2n(n1)CCCC2NC(=O)NC(C)c1cc(C)cc(C)c1 +O=C(Cn1nc(C(=O)N2CCCC2)ccc1=O)N1CCCC1 +Cc1ccn2cc(-c3ccc(NC(=O)c4ccoc4C)cc3)nc2c1 +CCN(C)c1cccc(NC(=O)C2CCOCC2)c1 +COc1cc2c(cc1F)CCNC2C=Cc1ccco1 +CCCc1ccc2oc(=O)cc(CNC(=O)CC)c2c1 +CC1(C)CN(C(=O)CCOc2ccc(Cl)cc2)CCO1 +Cc1ccccc1N1CCCN(C(=O)c2cccc(N(C)C)c2)CC1 +CC(=O)c1cnc(N2CCc3nnc(C(C)C)n3CC2)nc1C +COCc1nc(CN(C)C(C)c2ccccc2F)cs1 +O=C(Nc1ccc2c(c1)OCCCO2)c1cc(Cl)c2c(c1)OCO2 +c1ccc(Cn2cc(-c3nc(C4CCOCC4)n[nH]3)cn2)cc1 +Nc1nc2c(cc1C(=O)NCc1ccc(Cl)cc1)CCC2 +Cc1cc(-c2noc(CCC(=O)N(C)CCC#N)n2)ccc1F +COCCN1C(=O)CCC2(CNC(=O)c3ccc(C)nc3)CCCC12 +Cc1ccc2ncc(C(=O)N3CCN(C)CC3c3ccccc3)n2c1 +CCOC(=O)CC(NC)C(=O)c1ccc2c(c1)OCCO2 +O=C(CSc1ncnc2sccc12)NCc1ccco1 +O=C(c1ccncc1)N1CCC(OCCCc2ccccc2)C1 +C#CCN1C(=O)COc2cc(NCc3ccc(C)cc3)ccc21 +O=C(Cc1ccccc1Cl)N1CCC(=O)N(CC2CC2)CC1 +COc1ccc(NC(C)=O)cc1NCc1nc(C)no1 +COc1cccc(NC(=O)Nc2nnc(-c3ccsc3)o2)c1 +CCOC(=O)CN(c1ccc(Cl)cc1C#N)C1CC1 +CC(=O)Nc1ccc(CNc2cnn(-c3ncccn3)c2)cc1 +Cc1n[nH]c(C)c1-c1nc(N2CCCCC2)n(C)n1 +CNC(=O)NCC(=O)NCC1(Cc2ccccc2)CCCC1 +COc1cccc(C2CCCN2C(=O)C(C)Sc2ccccn2)c1 +CCOC(=O)c1cn[nH]c1-c1ccccc1OCC +CC(=O)Nc1cccc(-c2nc3ccc(C)cc3c(=O)o2)c1 +O=C(CCc1ccccc1F)NCc1nc2ccccc2[nH]1 +COC(=O)c1ccc2c(c1)nc(C1CC1)n2C(C)C +COc1ccc(Nc2nc(-c3cccc(N)c3)cs2)cc1OC +CCOC(=O)CCNC(=O)c1cc(-c2ccco2)on1 +COc1ccc(CCNC(=O)c2cc(NC(C)=O)ccc2O)cc1 +Cc1nc2ccc(NC(=O)c3ccccc3N(C)C(=O)C3CC3)cc2o1 +CC(NC(=O)CNC(=O)c1ccccc1F)c1cc2ccccc2o1 +CCCOc1ccccc1-c1nc(N)nc(C)c1C(N)=O +Cc1n[nH]c(C2CN(Cc3cccc(OC(C)C)c3)CCO2)n1 +OCC(CNc1nc2ccccc2o1)Cc1ccc(F)cc1 +CC(C)=CCN1CC2(CCN(c3nc(C(N)=O)cs3)CC2)CC1=O +COC(=O)NCCOC(=O)c1ccc(-c2ccc(F)cc2)o1 +Cc1cc(-c2nnc(CCC(=O)NCC(C)C)o2)n(C)n1 +COc1ccc(C2CC(=O)c3cc(Cl)cc(N)c3O2)cc1 +Nc1ccc(NCCS(N)(=O)=O)cc1C(F)(F)F +CCC(C)Nc1ncnc(Oc2cccc3ccc(C)nc23)c1N +Cc1cc(N)nc(SCCC(=O)Nc2ccccc2C#N)n1 +Cc1c(C(=O)Nc2nccs2)nnn1-c1ccccc1Cl +CC(C)n1cnc(S(=O)(=O)Nc2ccnn2Cc2cccnc2)c1 +CCn1c(C(=O)N2CCCC(c3noc(C)n3)C2)cc2ccccc21 +O=C(NCc1cc[nH]n1)NCC1CN(Cc2ccccc2)CCO1 +CCCNC(=O)C(C)N1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +CCOC1CCN(C(=O)c2c[nH]c3c(C)cccc3c2=O)CC1 +O=C1C(=O)N(Cc2ccccc2F)c2ccc(Cl)cc21 +O=C(NC1CC(=O)N(CCc2cccc(Cl)c2)C1)C1CCC1 +Cc1ccc(-c2c(C(=O)N3CCOCC3)csc2C)cc1 +Cn1cnc2c(F)cc(Br)cc2c1=O +Cc1nc(N2CCCC(C(=O)N3CCOCC3)C2)c2cnn(C)c2n1 +COCCCC(=O)N1CCCN(c2nc(C)cs2)CC1 +CCN(CC)C(=O)Nc1nncn1C(=O)N(CC)CC +CC1NCCc2c1sc1nc(-c3cccs3)nn21 +CC(CCc1ccccc1)NC(=O)c1ccc(-n2cnnn2)cc1 +Cc1ccc(NC(=O)N(C)C(C)c2ccco2)cc1-n1cnnn1 +CC(NC(=O)CN(C)S(=O)(=O)c1ccc(F)cc1)c1ccco1 +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1cc2c(s1)CCC2 +Cc1nnc(SCc2csc(-c3cnn(C)c3)n2)s1 +CC(=O)N1CCN(C2c3cccc(C)c3OCC2O)CC1 +Cn1c(C(NC(=O)COCC2CC2)c2ccccc2)nc2ccccc21 +COc1cc2c(cc1OC)CN(C(=O)C1CCCO1)CC2 +CS(=O)(=O)NC1CCN(Cc2cc(C(N)=O)cs2)C1 +CC(=O)c1c(F)cccc1NC(=O)OC(C)(C)C +Cc1ncsc1CCN(C)C(=O)Cn1c(=O)ccc2ccccc21 +C=CCNC(=O)Nc1ccc(NC(C)C(=O)NC2CC2)cc1 +CCC(=O)Nc1ncc(-c2ccc(Cl)c(Cl)c2)n1C +CCN(CC)C(=O)N1CCCC1CC(=O)c1cnn(C)c1 +Cc1nc(C)n(CC(=O)Nc2ccc(C(C)C)cc2)n1 +COc1ccc(C2CC(O)=Nc3c2cnn3C(C)C)c(F)c1 +CC(C)c1nc(CNC(=O)c2ccc(F)cc2)no1 +CC(C)COC(=O)c1ccc(S(C)(=O)=O)cc1 +COCc1ccccc1C(=O)Nc1ccc2[nH]c(C(F)F)nc2c1 +CC(C)Nc1cccc(CNC(=O)C2CCN(C(=O)N(C)C)CC2)c1 +CC(C)n1cc(NC(=O)Cc2c(F)cccc2F)cn1 +COc1ccnc(NC(=O)c2ccc3[nH]cnc3c2)c1 +COC(C)C(=O)N1CCN(Cc2cccs2)CC1 +CCc1cc(NC(C)c2n[nH]c(=O)[nH]2)n2nc(C)c(C)c2n1 +COc1c(Cl)cc(Cl)cc1C(=O)N1CCOCC1 +COc1cccc(C(N)=O)c1OCC(=O)Nc1cccc(C)c1C +CC(Sc1nncn1C)C(=O)NC1CCCCC1C +CCOCc1ccc(NC(=O)c2cccn2C)cc1 +Cc1ccc(OCC(=O)N2CCOC(c3noc(C)n3)C2)cc1 +Cc1cc(C)nc(NC(=O)NC(C)C(O)c2ccc(F)cc2)c1 +COc1ccc(OC)c(C2CCCN2c2ccc3n[nH]c(=O)n3n2)c1 +O=C(Cc1ccc(-n2cccc2)cc1)Nc1cc[nH]n1 +CCOc1ccc2[nH]c(SCC(N)=O)nc2c1 +O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc1ccccc1 +O=C(COCc1nc2ccccc2s1)Nc1ccc2c(c1)CCC2 +O=C(Cc1ccc(F)cc1)NC1CCN(c2ccccc2)C1=O +CN1CCC(NS(=O)(=O)N(C)C)C1c1ccc(Cl)c(F)c1 +CC(C1CC1)N(C)C(=O)CNS(=O)(=O)c1cn(C)cn1 +CNC(=O)c1ccc(CNC(=O)N(Cc2ccccc2)C2CC2)cc1 +O=C(CCN1C(=O)c2cccnc2Sc2ccccc21)NC1CC1 +Cc1ccc(NCc2noc(C(C)C)n2)c(OCC(=O)N(C)C)c1 +Cc1cnc(NC(=O)c2ccc(C)c(S(N)(=O)=O)c2)s1 +CSc1ccsc1C(=O)NCCNC(=O)c1cccnc1 +COc1cc(Cl)ccc1C(=O)NC1CCN(S(C)(=O)=O)CC1 +Cc1ccccc1CSc1nnc(-c2ccccc2)c(=O)n1N +O=C(c1ccc2c(c1)CCC2)N1CCCC(C(=O)N2CCOCC2)C1 +Cc1cnc(CCNC(=O)C2CCCN(C(=O)C3CC3)C2)s1 +O=C(CCCNC(=O)c1cccs1)Nc1cccc2cnccc12 +CCCN(CC(=O)OC)S(=O)(=O)c1cccc2cnccc12 +O=C(NCCNC(=O)c1cnn2c1OCCC2)c1ccccc1Cl +O=C1CCc2cc(C(=O)Nc3ccc(F)cc3)ccc2N1 +CC(C(=O)Nc1sc2c(c1C(N)=O)CCCC2)c1cccs1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)NC(C)(C)C)c1C +COc1nc(C)cc(C(=O)Nc2ccn(Cc3ccccc3F)n2)n1 +O=C(Cc1ccsc1)Nc1ncc(C#CCCO)s1 +O=C(c1cccnc1)N1CC(F)C(OCc2nc3ccccc3[nH]2)C1 +Cc1cccnc1CNC(=O)c1ccc(F)cc1N +CC(O)CNC(=O)c1nc(CC(=O)Nc2ccccc2)no1 +Cc1ccc(NC(=O)c2cccc(-c3nnnn3C)c2)c(C)c1 +CNC(=O)CC(NC(=O)c1ccccc1)c1ccccc1 +CCOC(=O)CNc1nc(C#N)nc(N2CCOCC2)n1 +CC1CC(C)CN(C(=O)c2ccc(O)c(Cl)c2)C1 +Cc1ccc(C)c(NC(=O)CN(C)C(=O)CCC2CCC(C)O2)c1 +CCCn1c(C2CC(=O)N(c3cccc(F)c3)C2)nc2ccccc21 +O=C(Cn1cc(-c2nnco2)c2ccccc21)NC1CC1 +Cc1noc(C(C)OC(=O)c2ccccc2OCc2noc(C)n2)n1 +C=CCSc1nnc(-c2cccs2)n1CC +Cc1ccc(CC(=O)NC(C)(C)c2cccc(F)c2)cn1 +Cc1cccc(C(=O)NCC(O)c2cccc(OC(F)F)c2)c1O +Cc1cnn(-c2ccncc2NC(=O)c2cc(C(C)C)n(C)n2)c1 +Cc1cc(CN(C)C(=O)c2cccc(OCC3CCCO3)c2)no1 +COc1ccc2c(c1)CCc1c(C(=O)NCC(C)C)noc1-2 +COc1ccccc1C1(CNC(=O)c2cccnc2)CCOCC1 +CC1COCCN1Cc1ncc(-c2ccc(F)cc2)o1 +Cc1n[nH]c(C)c1S(=O)(=O)N(C)C1CCCC1 +CCNC(=O)c1cccc(NC(=O)c2cccc3c2OCO3)c1 +Cc1nc(-c2cc(C(=O)N(C)C3CCCCC3)n(C)c2)cs1 +CCOCCCNc1nc2ccc(N)cc2s1 +O=C(Cn1cccc(C(F)(F)F)c1=O)Nc1cccc2cn[nH]c12 +CCN(CC)S(=O)(=O)N1CCN(c2nccs2)CC1 +CC(C)c1ncc(C(=O)N(C)CCc2ccccn2)cn1 +COCCn1cc2c(n1)C(NS(=O)(=O)c1cccnc1)CCC2 +COCCNc1ncnc2c1cnn2-c1ccc(F)cc1 +OCCN1CCN(c2nc(-c3cccnc3)nc3ccccc23)CC1 +CNS(=O)(=O)c1ccc(NC(C)C2CCCO2)cc1 +O=C1CC(c2cccc(Cn3cccn3)c2)c2cc3cn[nH]c3cc2N1 +COCCCNC(=O)c1snc(-c2ccncc2)c1N +NC(=O)Nc1cc(N2CCCS2(=O)=O)ccc1F +Cc1cc2c(C)cc(=O)[nH]c2cc1S(=O)(=O)NCC(C)(C)C +c1ccc(-c2ncn(CC3CCCCO3)c2-c2ccco2)cc1 +CC(O)CNC(=O)NCc1cccnc1OC1CCCC1 +Cc1ccc(NC(=O)CSc2nc(=O)[nH]cc2C)cc1F +Nc1ncc(Cc2ccc(Cl)cc2Cl)c(N)n1 +O=C(Cn1cc(C2CC2)nn1)N1CCC(Oc2cccc(Cl)c2)C1 +CCc1nnc(NC(=O)c2sc3ncn(C)c(=O)c3c2C)s1 +CCN1CC(C(=O)OCC2CC=CCC2C)CC1=O +Cc1cc2nc(N3CCC(O)CC3)c3ccccc3n2n1 +COc1cccc(OC)c1COC(=O)C1CCCO1 +Cc1cc(C(NC(=O)N(C)Cc2ncnn2C)C(C)C)c(C)s1 +CN(C(=O)C1CC1)C1CCN(c2ccc(F)cc2)CC1 +CCC(C)C(=O)N1Cc2ccccc2CC1C(=O)Nc1nccs1 +CC1CCN(C(=O)c2cccc3cnccc23)CC1 +Cc1nn(CC(=O)Nc2cccc(Cl)c2)c(=O)c2noc(C)c12 +Cc1ccccc1N(C)C(=O)Cn1ncc2c([nH]c3ccccc32)c1=O +C=CCNC(=O)c1ccc(NC(=O)c2ccc(F)c(C)c2)cc1 +Nc1cccc(Cl)c1SCC(=O)NC1CCCCC1 +COc1ccc(CCNc2nc(C)nc3sc(C)cc23)cc1OC +CCC1(NC(=O)NC2CCC(Oc3ccc(C#N)cn3)CC2)CCC1 +COC(=O)c1cc(CNC(=O)Nc2ccncc2)oc1C +Cc1ccoc1C(=O)OCC(=O)Nc1sccc1C(N)=O +CC(C)(C)C(=O)NC(C#N)c1ccc(Cl)cc1 +CC(C(=O)NCc1cccnc1OCc1ccccc1)n1cncn1 +COc1ccc(C(C)NC(=O)c2cn3c(n2)COCC3)cc1OC +CCc1nnnn1Cc1nc(-c2ccccc2C)no1 +CCCN(CC(F)(F)F)CC1(CO)CCCC1 +Cc1c(O)ccc(C(=O)CN2CC(C)OC(C)C2)c1O +COC(=O)c1ccc(Br)c2c1NCCC2 +COCCCN(C)C(=O)c1ccccc1Br +CCCc1onc(C)c1C(=O)OCC1CCCN1c1ccc(C)nn1 +COc1cc(OC)c(C(=O)Nc2cccc(C(C)=O)c2)cc1OC +CC(C)CCOC(=O)CC1C(=O)NCCN1C(=O)C(C)(C)C +O=C(Nc1ccn(-c2ccncc2)n1)c1cccc(OC2CCCC2)c1 +Cc1ccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)cc1N +Cc1cc(Br)ccc1NC(=O)CN(C)C(=O)C1CC1C +O=C(NCC1(c2ccccc2)CC1)N1CCCC(O)C1 +CCCNC(=O)CNC(=O)c1ccc(N2CCNC2=O)cc1 +CC(C)(C)NC(=O)c1cccc(NC(=O)c2cccc(F)c2)c1 +CCn1ccc(C(=O)Nc2ccsc2C(=O)OC)n1 +O=C(c1cc2c(s1)CCC2)N1CCCCC1C1OCCO1 +Cc1ccc(CN(C)C(=O)Cc2c[nH]c3ccccc23)o1 +Cc1nc2cc(-c3noc(-c4ccco4)n3)ccc2o1 +NC(=O)c1cccc(CNC(=O)NCC2CN3CCCCC3CO2)c1 +CCNc1nnc(-c2cnc(N(CC)CC)s2)s1 +CCC(=O)Nc1ccc(O)c(C(=O)NCc2cccnc2)c1 +Cn1cc(CCC(=O)NC2CCCNC2=O)cn1 +CC1CCN(S(=O)(=O)NCCCn2cncn2)CC1 +CC(C)n1c(CCNC(=O)c2cccc(F)c2)nc2ccccc21 +CCN(CC(C)C#N)C(=O)c1ccc(Br)cc1O +O=C(CSc1ccccc1)Nc1ccccc1C(=O)N1CCCC1 +CN(C)S(=O)(=O)NCC(C)(C)c1ccccc1Cl +Cc1ccn2c(=NC(=O)C3CC=CCC3)[nH]nc2c1 +COc1cccc(C(=O)C2CCN(C(=O)CC(C)C)CC2)c1 +CC(Sc1nnc2ccccn12)C(=O)NCc1cccs1 +O=C(c1ccccc1)N1c2ccccc2C(=O)C12CC2 +N#Cc1ccncc1NCc1cc(Cl)ccc1F +CC(=O)Nc1nnc(SCC(=O)N2CCCCC2)s1 +CN(c1cccc2ncccc12)S(=O)(=O)c1ccc(C#N)cc1 +CC(Oc1ccccc1NC(=O)CN1CCOCC1)c1ccccc1 +CCOc1ccc(NC(=O)NCCc2c(C)nn(C)c2C)cc1 +Cc1ccccc1CN1CCN(CC(=O)c2cccs2)CC1 +Cc1nn(C)c(C)c1CC(=O)N(C1CC1)C(C)c1ccccc1Cl +CCN(CCC#N)C(=O)CSc1nc2ccccc2c(=O)n1C +CN(Cc1ccco1)C(=O)NCCc1ccc2c(c1)OCO2 +NS(=O)(=O)c1ccc(CCNC(=O)Nc2cccnc2)cc1 +CCCCNC(=O)C1CCCN(C(=O)Nc2c(C)noc2CC)C1 +Cn1c(N)nnc1SCCOc1cc(Cl)ccc1Cl +Cn1c(N2CCC(O)C2)nc2cc(C(=O)NCC3CC3)ccc21 +Cc1ccc(NC(=O)NCCNC(=O)C(C)C)cc1Br +CN(CCN1CCOCC1)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +Cc1nc(C)c(-c2coc(N)c2C(=O)c2ccco2)s1 +CC(c1cccnc1)N(C)C(=O)Nc1nnc(-c2ccsc2)s1 +CCn1nnc(-c2cccc(-n3ccnc3-c3ccc(C)o3)c2)n1 +Cc1cc(C)c(NC(=O)c2csc(Nc3ncccn3)n2)c(C)c1 +O=C(c1cnccn1)N1CCCC(c2nc(-c3ccccc3)n[nH]2)C1 +Cc1cc(C)c2c(NCc3cnc(N(C)C)nc3)n[nH]c2n1 +CC(C)n1nccc1NC(=O)c1c[nH]c2ccc(F)cc2c1=O +CCN(CC)C(=O)c1ccc(=O)n(Cc2ccccc2)n1 +CC(Oc1cccc(C(C)(C)C)c1)C(=O)N1CCNC(=O)C1 +Cc1nn(Cc2cn3ccccc3c2C#N)c(N)c1C#N +CS(=O)(=O)c1cccnc1C1CCCN(Cc2ccccn2)C1 +COc1ccccc1NCc1c(C)cc(O)cc1C +O=C(NCc1cnn(-c2ccccc2)c1)c1cc(-c2cccnc2)on1 +N#Cc1nc2c(nc1C#N)-c1cccc3cccc-2c13 +Cn1nc(C(C)(C)C)cc1NC(=O)CN1CCOCC1 +Cc1cc(-c2ccc(F)c(F)c2)c(C#N)c(=O)n1C +COc1cccc(C(=O)Nc2cccc(-n3cnnn3)c2)c1OC +O=C(Cc1cnc2ccccc2c1)NCCC(=O)Nc1cccnc1 +CCOC(=O)CCC1NCCc2ccc(C)c(F)c21 +O=C(CCC1Nc2ccccc2S1)OCC(=O)C1=NC=CC1 +Cc1ccc(-n2nnnc2CNC(=O)NC2CCCCC2)cc1C +CC(C)(C)CC(=O)NCc1ccc(CN2CCCC2=O)cc1 +CCOc1ccc(NC(=O)C(C)Oc2cccc(N)c2)cc1 +CC(NC(=O)c1ccc(Cn2cc(Cl)cn2)o1)c1ccccc1 +Cc1noc2nc(C3CC3)cc(C(=O)NCc3ccccc3)c12 +CCOC(=O)C1CCCN(C(=O)c2cccc(Br)c2)C1 +COc1ccccc1CNc1ncnc2cc(OC)c(OC)cc12 +Cc1cccc(OCCSc2nnc(N)n2C2CC2)c1 +Fc1ccc(-n2ncc3c(NC4CCc5ccccc54)ncnc32)cc1 +CCc1cccc(OCCSc2nnc(C)c(=O)n2N)c1 +COCCCNC(=O)c1cc(Cl)c(OC)c(OC)c1 +CCOC(=O)CN(C)C(=O)c1cc(C(C)(C)C)n[nH]1 +Cc1ccnc(NC(=O)c2ccc(S(C)(=O)=O)cc2)c1 +CCn1cc(S(=O)(=O)N(CCCO)C2CCc3ccccc32)cn1 +CC(Nc1ccccc1)C(=O)NCc1ccc2c(c1)OCO2 +COc1nc2ccccc2nc1NC1CCC(O)CC1 +Clc1cccc(NCc2cccnc2)c1Cl +CCOC(=O)CNC(=O)N1CCCC(Nc2cccc(F)c2)C1 +Cc1nn(C)c(NS(=O)(=O)c2ccc(C#N)c(Cl)c2)c1C +COc1cccc(C(=O)NCC(=O)Nc2ccc(CC#N)cc2)c1 +CCOc1ccc(-c2ccc(C(=O)OC)o2)cc1N +O=c1c2c([nH]c3cc(C4CC4)nn13)CCN(Cc1cccnc1)C2 +CCC(NC(=O)Cc1ccc(C)nc1)c1nc(-c2ccccc2)c[nH]1 +O=C1CC(C(=O)NCc2ccccc2)NC(N2CCOCC2)=N1 +CN(C)S(=O)(=O)NCc1cc(F)ccc1Br +CCc1nc2n(n1)CCCC2NC(=O)NCCc1cccnc1 +CNC(=O)CN(c1ccc(Cl)cc1C)S(C)(=O)=O +CCc1ccc(NC(=O)c2ccc(=O)n(C)n2)cc1 +CCc1ccccc1OC(C)CC(=O)N1CCNCC1 +CCOC(=O)C1CCN(c2nc(C)nc3c2CN(C(C)=O)CC3)CC1 +CCC(C)C(C)NC(=O)c1cnc2ccc(C)cn12 +CCCCN(C)C(=O)COc1c(C)occc1=O +COc1cccc(C(=O)N(C)Cc2ccc(Br)cc2)c1 +N#Cc1ccc(NCc2nc3ccccc3s2)cc1 +CSc1nc2nc(C)c(CC(=O)NC(C)C)c(C)n2n1 +CCCn1cc(NC(=O)NC(C)c2ccc(C)c(F)c2)cn1 +Cc1cc(F)ccc1S(=O)(=O)Nc1ccc(C(=O)NC2CC2)cc1 +NC(=O)c1ccc(C(=O)N2CCOCC2C2CC2)nc1 +CC(=O)C1(c2ccc(Br)cc2)CCCCC1 +CCNC(=O)CNC(=O)c1cc(C)n(Cc2cccs2)c1C +CCCC(C)(C)NC(=O)c1ccc(Cn2cncn2)cc1 +CNC(=O)C(C)CN(C)C(=O)c1cnc(Cc2ccccc2)s1 +FC(F)CN1CCN(Cc2cc(-c3cccs3)on2)CC1 +CC(=O)N1CCc2cc(S(=O)(=O)Nc3cccc(F)c3)ccc21 +NS(=O)(=O)CCNc1ccc2nnc(-c3ccccc3)n2n1 +COCC(C)NC(=O)NCc1ccc(OC2CCCC2)nc1 +COCCNC(=O)CCc1ccc(N2CCCC2)c(N)c1 +Fc1ccccc1OCCn1nnc(-c2ccccc2)n1 +CCCc1nc(CN(C)S(=O)(=O)c2cccs2)no1 +COC(=O)c1c(O)ccc(-c2ccc(OC)cc2)c1C(=O)OC +Cc1cc(C)c(NC(=O)c2cc(F)cc(F)c2)c(C)c1 +CN1C(C(=O)c2ccccc2)C(=O)c2ccccc2S1(=O)=O +Cc1occc1C(=O)N1CC(N2CCCC2=O)C2OCCCC21 +O=C1CCCCCN1Cc1nc(C(O)c2ccccc2)nn1CCO +CN(C(=O)CCNC(=O)Nc1ccc(Br)cc1)C1CC1 +O=C(NCCc1ccncc1)c1ccc(-c2cc[nH]n2)cc1 +Nc1cc(NC(=O)COCc2ccccc2)ccc1Cl +CC1(C)C(NC(=O)CCc2nc(-c3ccoc3)no2)C2CCOC21 +O=C(NCCc1ccc(F)cc1)c1sccc1C1CC1 +CCOc1c(Cl)cc(C(=O)N(C)Cc2ccc(C)o2)cc1OC +Cc1ccc(S(=O)(=O)CNC(=O)Nc2ccccc2C)cc1 +O=C(NCCOCCO)Nc1ccc(Cl)cc1 +CC(C(=O)Nc1cccc2c1OCCO2)c1cccs1 +CCc1noc(CC)c1CC(=O)NC(C)Cc1c(C)nn(C)c1C +c1cnc2nc(SCc3cn4ccccc4n3)oc2c1 +O=C(NCc1nncn1C1CC1)Nc1ccc2c3c(cccc13)CC2 +COCc1ccccc1NC(=O)Cc1csc(-c2ccc(C)o2)n1 +CC(C)c1ccccc1OCCc1nc(CO)cs1 +COc1ccc(-c2noc(-c3ccccc3F)n2)cc1OC +CC=CCCNC(=O)c1ccc(-n2ccnn2)cc1 +CC(=O)c1cccc(-n2nnc(-c3ccccn3)c2N)c1 +CC(=O)c1cccc(S(=O)(=O)Nc2ccc(C)cc2)c1 +O=C(Nc1ccc(NC(=O)c2ccco2)cn1)c1ccccc1 +CCN1CC(Nc2cc(C)nc(-c3cccnc3)n2)CC1=O +CCc1ncc(Br)c(-c2ccccc2F)n1 +Cc1ccnc(NC(=O)CSc2nnnn2-c2ccccc2)c1 +CCc1onc(C)c1NC(=O)C1CCN(c2ccc(Cl)cn2)CC1 +CC(C)CCNC(=O)c1cc(-n2cnnn2)ccc1Cl +CC(C)CNC(=O)c1ccc(NC(=O)NC(C)c2ccccn2)cc1 +O=C(Cn1cncn1)NCCCN1CCOCC1 +CC(C)N(CCC#N)S(=O)(=O)N1CCCCCC1 +Cc1ccc(-n2c(SCCC#N)nnc2-c2ccncc2)cc1 +Cc1ccnc(NC(=O)C(C)OCC2CCCCO2)c1 +C=CCNC(=O)CN1C(=O)c2ccccc2S1(=O)=O +Cc1cc(NC(=O)COc2ccccc2)c2cc(F)cc(F)c2n1 +COCCN(C)C(=O)NCC(C)(C)c1ccc(F)cc1 +CCn1ncc(C(=O)N2c3ccc(F)cc3CCC2C)c1C +CCCNC(=O)CNC(=O)NC1CCc2ccccc21 +CC1(C)CCN(S(=O)(=O)c2c[nH]nc2N)CC1 +Cn1ncc2c(Nc3ccc(Cl)cc3)nc(NCCO)nc21 +Cc1nc2nc(-c3ccccc3)cc(-c3cccnc3)n2n1 +CC1CN(C(=O)C2CCCOC2)c2ccccc2S1 +Cc1c(C(=O)N2CCOCC2)oc2ccc3c(c12)C(O)CC(C)(C)O3 +O=C(Cn1ncc(=O)c2ccccc21)N1CCCC(n2cccn2)C1 +COc1ccc(S(=O)(=O)NCc2ccccn2)cc1C +Cc1nc(N2CCN(C(=O)C(C)(C)C)CC2)cc(-n2cccn2)n1 +CC1(C(=O)N2CCC(n3cc(CO)nn3)CC2)CCCCO1 +CC(CO)C(C)NC(=O)Nc1cccc(N(C)C(C)C)c1 +NS(=O)(=O)c1ccc(C(=O)NCCc2ccccc2F)cc1 +CCCn1nccc1NC(=O)c1ccc2c(c1)CCN2C(=O)CC +Cc1cc(Br)ccc1NS(=O)(=O)c1ccc(O)cc1 +Cc1csc(NC(=O)C2CC(=O)N(CC(F)(F)F)C2)n1 +O=c1ccccn1Cc1ccc(-n2cccn2)cc1 +O=c1[nH]c(=O)c2ncn(C3OC(CO)C(O)C3O)c2[nH]1 +CCn1cc(N)cc1C(=O)N(C)Cc1cscn1 +Cc1c(C(=O)N2CCOC3(CCOCC3)C2)sc2nccn12 +N#Cc1ccc(S(=O)(=O)Oc2ccc(-n3ccnc3)cc2)cc1 +Cc1ccc(CN(C)S(=O)(=O)c2cccc(F)c2)s1 +CC(C)C(Cn1nc(-c2cccs2)ccc1=O)NC(=O)C1CCC1 +CCc1nnc(Cn2cnc3sc4c(c3c2=O)CCC(C)C4)o1 +O=C(COC(=O)Cn1ncc(=O)c2ccccc21)NCC1CC1 +COC(=O)c1c(C)[nH]c(C(=O)CSc2nc3ccccc3o2)c1C +CCC(CC)C(=O)Nc1cc(C(C)=O)ccc1OC +Cc1oc(C(=O)NCCCO)cc1S(=O)(=O)N1CCCC1 +CCCNC(=O)CN(C)C(=O)c1cc2c(nc3sccn32)s1 +CN(Cc1cnn(C)c1)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +Cc1cc(NC(=O)c2ccc(C(=O)Nc3cc(C)on3)nc2)no1 +Cn1cc(NC(=O)c2ccc(CN3CCCCC3=O)cc2)cn1 +CCOCC1CCCN1C(=O)c1ccc(-n2nc(C)cc2C)cc1 +Cc1ccc(OCC(=O)Nc2sc(C)c(C)c2C(N)=O)c(C)c1 +COC(=O)C1=Nc2nnnn2C(c2ccc(C)cc2)C1C(C)=O +CC1CCCCN1C(=O)CCNC(=O)c1cnn2cccnc12 +CC(NC(=O)Nc1ccncc1)c1ccc2c(c1)NC(=O)CO2 +O=C(NCc1cnn(Cc2ccccc2)c1)Nc1c(F)cccc1F +COc1ccc(-c2noc(CCn3nc(C)cc3C)n2)cc1 +Cn1cccc1C(=O)OCc1cc(-c2ccco2)on1 +CN(CCCNC(=O)Nc1ccccc1)c1ccccc1 +CC(C)(C)NC(=O)c1cccc(NC(=O)c2c(F)cccc2F)c1 +CC(C)Cc1nnc(NC(=O)NCc2ccc3c(c2)OCO3)s1 +COc1cccc(Cn2nccc2NC(=O)c2ccccc2)c1OC +CCCn1nccc1C(=O)Nc1ccccc1C(F)(F)F +O=C1CN(C(=O)C2CCC2)CCN1CC1CCCC1 +CC(CO)NC(=O)c1ccccc1CSc1nc2ccccc2o1 +Cc1c(CNC(=O)C2(C#N)CCCC2)oc2ccccc12 +NC(c1nc2cccnc2s1)c1ccccc1F +O=C1CN(C(=O)c2ccnc(-n3cncn3)c2)CCN1 +O=C(CCCNC(=O)c1cccs1)NCc1cscn1 +CCc1ccc(CCNC(=O)N2CCOCC2C)cc1 +CC1=C(C(=O)NC(C)c2cnn(-c3ccccn3)c2C)OCCO1 +C=CC1NCCc2cc(OC)c(O)c(Br)c21 +Cc1cc(NCc2cccc3cn[nH]c23)ccc1-n1cnnn1 +CC1(C)Oc2ccc(NC(=O)c3ccc[nH]3)cc2O1 +Cc1ccc(NC(=O)NCC2(C)COC2)cc1S(C)(=O)=O +Cc1nc(-c2cnn(C)c2)nc2c1CN(C(=O)c1ccc[nH]1)CC2 +CCC(=O)Nc1ccc(NC(=O)c2c(C)nc3ccccn23)cc1 +Cn1c(CCNCc2ccc(F)cc2)nc2cc(F)ccc21 +Cc1ccnn1-c1cccc(NCc2cc(C(N)=O)cs2)c1 +CCOC(=O)CN(CC)C(=O)Cc1cccc(Cl)c1 +N#Cc1cccc(NC(=O)NCCc2nc3ccc(F)cc3[nH]2)c1 +O=C(NCCc1csc(-c2ccccc2)n1)NC1C=CC(CO)C1 +CC(C)(C)Oc1cc(CNC(=O)NCC2CCCC(O)C2)ccn1 +Cc1ccc(CNC(=O)c2ccc[nH]2)c(OCC2CCCO2)c1 +c1coc(-c2cnc(NCCN3CCOCC3)nc2-c2ccco2)c1 +CC1CN(C(=O)CSc2ccccc2F)CCO1 +CCC1CCCCN1C(=O)C1CCN(C(=O)Nc2cccs2)CC1 +Cc1ccc(-c2nnc(NC(=O)c3cc(C)nn3C(C)C)o2)c(C)c1 +O=C(CNC(=O)c1ccccc1)NCCOc1cccc2cccnc12 +COC(=O)C(C#N)CC(=O)c1ccc(OC)c(C(C)C)c1 +c1cc2c(cc1CNc1nnc(C3CC3)o1)CCCC2 +CC(C)OCc1ccc(CNC(=O)C2CCC2)cc1 +CCS(=O)(=O)N(CCCO)c1cccc(F)c1 +COc1cccc2c(C)c(C(=O)N3CCC(CNC(C)=O)CC3)oc12 +Cc1cc(NC(=O)Cn2nc(C)c(Cl)c2C)no1 +CCCCNC(=O)c1cnn2c(-c3ccc(OCC)cc3)ccnc12 +Cc1ccc(C)c(OCC(=O)N(C)c2ccc(S(C)(=O)=O)cc2)c1 +COc1ccc(C2(Cc3ccccc3F)NC(N)=NC2=O)cc1 +CNC(=O)C1CCN(S(=O)(=O)N2CCC(C(C)(C)C)CC2)CC1 +C#CCNC(=O)c1ccccc1NC(=O)c1cc(F)ccc1C +COc1ccc(C(=O)N(C)c2ccc(F)c(F)c2)c(F)c1 +N#Cc1cc(F)cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +CC(=O)c1ccc(Nc2ncnc(N3CCOCC3)c2N)cc1 +CCC1CCCC(NC(=O)c2ccc(=O)n(CCOC)n2)C1 +COc1ccc(F)c(NC(=O)N(C)C(C)c2ccco2)c1 +CCCCn1c(N)c(NCc2cn[nH]c2)c(=O)n(C)c1=O +CCC1CCCC(NC(=O)NCCOc2cccnc2)C1 +Cc1nnc(-c2ccccc2NC(=O)c2csc(C(C)(C)C)n2)o1 +CN(C)c1ccccc1C1CCc2nc(N)nn2C1 +Cn1cc(C(=O)Nc2cccc(Cl)c2)ccc1=O +COc1cc(C)ccc1CNC(=O)c1cccnc1OCC(F)F +CSc1ncccc1C(=O)NC1CCC(C)CC1 +CCCC(=O)N1CCN(c2c(C)n[nH]c2C)CC1 +Cc1noc(C(C)C)c1C(=O)NCc1cccc(S(N)(=O)=O)c1 +CC(C)CCCCNC(=O)Cn1ncc(=O)c2ccccc21 +Nc1cc(Cl)cc2c1CCN(CCN1CCOCC1)C2 +COc1ccc(CNC(=O)Cn2cc(N)cn2)cn1 +Cc1cc(NC(=O)c2ccn(C3CCCC3)n2)no1 +COc1ccc2ccn(CC(=O)Nc3cccc(Cl)c3)c(=O)c2c1 +CNC(=O)c1cc(C2CCN(S(C)(=O)=O)CC2)ncn1 +CC(Cc1ccccc1F)NC(=O)c1cc2c([nH]c1=O)CCCC2=O +Cc1ccc(C(=O)N(C)Cc2ccc(O)cc2)cc1C +CC(CNC(=O)c1cccc(-n2cccn2)n1)c1cccs1 +O=C(NCc1ccnc(OCC(F)(F)F)c1)NC1CCC(O)CC1 +COc1cccc(C(C#N)NC(=O)c2ccsc2)c1OC +CC1CCN(c2cc(NC(=O)Cc3c[nH]c4ccccc34)ncn2)CC1 +CC1=Nc2nc(CCCO)nn2C(c2ccccc2F)C1C(N)=O +CCC(=O)Nc1ccc(S(=O)(=O)NCCc2ccoc2)c(C)c1 +CCn1nc(C)c(NC(=O)NCc2cccc(COC)c2)c1C +O=C(Nc1ccccc1)c1ccc(CN2CCOCC2C2CC2)cc1 +O=C(c1cccc(-n2cnnn2)c1)N1CCN(c2nccs2)CC1 +COCCC(=O)N1CCC(c2cc(=O)[nH]c(-c3ccccn3)n2)C1 +Cc1cccc(OCC(CC#N)N2CCOCC2)c1 +Cc1ccncc1NC(=O)N(C)C(C)c1cccnc1 +Cc1ccc(CCNc2ncnc3[nH]cnc23)c(C)c1 +CCc1cc(=O)n2c(n1)SCC2CC(=O)NC(C)C +CC(C)OC(=O)c1cccc(OCC2CCCO2)c1 +CC(=O)NCC(=O)N1CCCC1c1ccc(C(C)C)cc1 +Cc1cc(NC(=O)NCC2(N3CCOCC3)CCCCC2)no1 +COC1CCN(C(=O)c2cc(C)no2)CC1Cc1ccccc1 +CC=CCCNC(=O)c1cnc(Cc2ccccc2)s1 +CCOC(=O)CN(C)C(=O)c1ccc(N(C)C)nc1 +Cc1nn(C)cc1C(=O)N1CCCC(C(=O)Cc2ccccc2)C1 +O=C(c1cc(Cl)ccc1F)N(CC(F)(F)F)C1CC1 +COc1ccc(C(=O)NCC(C)(O)c2ccc(F)cc2)nn1 +CCNC(=O)c1cccc(NC(=O)N2CC(C)OC(C)C2)c1 +CS(=O)(=O)c1ccc(C(=O)Nc2ccnn2C2CCCC2)cc1 +CN(C)C(=O)c1ccc(NC(=O)NCCO)cc1 +Cc1ccc(C(C)NC(=O)c2scnc2C)cc1F +COc1ncccc1CNC(C(N)=O)c1ccccc1 +CCNC(=O)Cc1csc(NC(=O)Nc2ccc(Cl)cc2)n1 +Cc1nn2cccnc2c1C(=O)Nc1ccc(N2CCCC2)nc1 +CC1CN(c2oc(COc3ccccc3)nc2C#N)CC(C)O1 +CS(=O)(=O)c1ccc2c(c1)CCCN2C(=O)C1CCC1 +CCCC(C)NC(=O)c1cc(N(C)S(C)(=O)=O)ccc1Cl +C=CCNC(=O)Cn1nc(-c2cccs2)oc1=O +Cc1ccc(C2NCCc3c2ccc(Cl)c3F)cn1 +NC(=O)C1(CNC(=O)c2cc(-c3ccccc3)no2)CCOCC1 +Cc1cnc(NC(=O)c2cccc(-n3cnnn3)c2)s1 +O=C(CNc1ccc(Br)cc1)NCc1ncc[nH]1 +Cc1nc2cc(NCc3c[nH]nc3-c3cccnc3)ccc2o1 +CN(C1CC1)S(=O)(=O)c1ccc(C#CCO)cc1Cl +CCCNC(=O)c1cccc(C(=O)Nc2cnn(C)c2)c1 +C#CCOc1ccc(NC(=O)c2cc(F)ccc2F)cc1 +Cc1ccc(-c2nc(N3CCC(C)CC3)ncc2-c2ccncc2)cn1 +CSc1ccc(S(=O)(=O)N(C)C)cc1C(=O)N1CCCC1 +CCc1ccsc1C(=O)NCC(=O)NCCN1CCOCC1 +Cc1ccc(NC(=O)COc2nccc(C)n2)cc1 +COc1ccc(C(=O)N2CCOCC2(C)C)cn1 +C=CCSc1nnc(NC(=O)C2CCC2)s1 +COc1ccc2c(c1)CCCC2NC(=O)CCc1scnc1C +CCc1nnc(-c2ccc(NC(=O)NC(C)Cn3cncn3)cc2)o1 +CN(Cc1ccco1)Cc1nnc(-c2ccc(Cl)cc2)o1 +O=C(CN1CCOCC1)Nc1cc(-c2cccc(F)c2F)n[nH]1 +CCNc1ccc(Cl)c(C(=O)N(C)CC(C)(C)C)n1 +COC(=O)c1cccc(OCCSc2nc(C)n[nH]2)c1 +CC1(C)CN(C(=O)c2ncn(-c3ccccc3)n2)c2ccccc2O1 +COc1cccc(C(=O)Nc2cnn(C(C)C)c2)c1 +COCCNC(=O)N1CCN(CC(=O)NCc2ccccc2)CC1 +Cc1cccc(S(=O)(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +CCc1cnccc1C(=O)Nc1cccc(NC(=O)NC)c1 +COCCOCC(=O)Nc1ccc(F)cc1Cl +Cn1cc(NC(=O)Nc2ccccc2SC2CCCC2)cn1 +COc1ccc(Cn2cc(C(=O)N(C)Cc3ccon3)nn2)cc1 +Cn1cnnc1SCc1ncnn1-c1ccc2c(c1)OCCO2 +CC(C)CCOc1ccc(C(=O)NCC2CN3CCCC3CO2)cc1 +CC(=O)Nc1ccc2nc(NC(=O)c3ccc(F)cc3)oc2c1 +O=C(CCNc1cccc(F)n1)NC1CCCCC1 +Cc1ccc(C(=O)N2CCN(C(=O)CCCO)CC2)cc1 +Cc1noc(C2CC3CCN(C(=O)c4ccco4)CC3O2)n1 +O=C(c1ccccc1)c1cc2ccccc2oc1=O +CCCc1noc(CCC(=O)Nc2ccc3c(c2)OC(F)(F)O3)n1 +CN(C)S(=O)(=O)Oc1cccc(NS(C)(=O)=O)c1 +Cc1occc1C(=O)N1CCC(NS(C)(=O)=O)CC1 +Cn1cc(CCCn2c(-c3cccnc3)noc2=O)cn1 +CC(C)Cc1nc(C(=O)NC(C)Cn2ccnc2)cs1 +COc1cc(COCC2CCN(C(=O)C3CC3)CC2)cc(OC)c1 +Cc1nccn1-c1cncc(C2CCCN2Cc2ccc(F)cc2)n1 +CCCc1cc(C(=O)NCCNc2ncccn2)[nH]n1 +Cc1csc(C(C#N)C(=O)c2cnn(C(C)(C)C)c2)n1 +COC(=O)C(Cc1ccccc1)NC(=O)c1ccc2ccccc2n1 +O=C(Nc1ccc(-n2ccnn2)cc1)NC1C2CCC(C2)C1CO +COc1cc(O)cc2c1CCNC2c1cncnc1 +CCNc1ccc(C(=O)N2CCc3ccccc32)cc1 +COC(=O)C(C)CNC(=O)Nc1ccc(C)c(OC(F)F)c1 +Cc1csc(N2CCN(C(=O)C(C)NS(C)(=O)=O)CC2)n1 +Cc1ccc(C(C)NC(=O)COc2ccccc2Cl)o1 +Cn1cc(C(=O)Nc2cccc(C#Cc3ccccn3)c2)ccc1=O +COc1ccccc1SCC(=O)N(C)CCC#N +CCc1ccccc1NC(=O)CN(C)C(=O)c1ccc[nH]1 +CCN1CCN(C(=O)CN(CC)S(=O)(=O)c2ccccc2)CC1 +Cc1nn(C)c(=O)c(C(=O)NCCc2cc(F)cc(F)c2)c1C +CCc1onc(C)c1NC(=O)NCC1CCCOC1C(C)C +O=C1CCCN1CCCSc1nnc(NC2CC2)s1 +CNc1cc(C2CCN2S(=O)(=O)c2ccccc2)nc(C)n1 +COC(=O)c1ccc2c(c1)CN(CC(F)(F)F)CC2 +CCc1ccccc1NC(=O)CSc1nncn1N +CCn1c(SCc2ccc(F)cc2)nnc1-c1cnccn1 +CC(Cc1nc(-c2ccc(C#N)cn2)no1)NC(=O)C1CCCC1 +Cc1[nH]c2ccccc2c1C(=O)C(C)Sc1ncccn1 +O=S(=O)(NCC1CCCC1O)c1cccc2ccccc12 +Cc1cccc(C(=O)N2CCC(C(=O)N3CCCC3)CC2)c1O +CN(CC(=O)Nc1cccc(Nc2ccccc2)c1)S(C)(=O)=O +Cc1cc(C)cc(N2CC(c3nc(-c4ccccn4)no3)CC2=O)c1 +Cc1nc2ccc(NC(=O)Cn3ccc4ccccc43)cc2o1 +CCCCS(=O)(=O)N(C)CC(=O)Nc1cccc(Cl)c1 +CCCC(=O)Nc1ccc(CC(=O)NC(C)c2csc(C)n2)cc1 +NC(=O)C(Sc1nnnn1C1CCCC1)c1ccccc1 +O=C(Cc1csc(N2CCCC2=O)n1)NCc1ccco1 +CCOC(=O)c1c(C)c(C(=O)NC2CCCCC2)c(C)n1CC +CCOC(=O)c1cnc(SC(C)C(=O)NC2CCCC2)nc1N +O=C(c1ccc(SCC(=O)N2CCCCC2)cc1)C1CC1 +O=C(COC1CCCC1)Nc1ccc(-n2nccn2)cc1 +COc1ccc(N(C(=O)c2cc(C(N)=O)cn2C)C(C)C2CC2)cc1 +CC1COCC(C)N1CC(=O)NCc1ccc(OC(F)(F)F)cc1 +CCc1ccsc1C(=O)Nc1ccc2c(c1)CC(=O)N2 +COc1cc(C#N)ccc1OCc1cc(Cl)cc2c1OCOC2 +CSc1cccc(NC(=O)COc2ccc(F)c(F)c2)c1 +COCCn1cnnc1SCC(=O)Nc1ccccc1F +Cc1ccn(S(=O)(=O)c2ccc(Cl)c(Cl)c2)n1 +Cc1cccc(C(=O)NCc2ccc3c(c2)OCCO3)c1C +COC(=O)c1nsc(C(=O)Nc2ncccn2)c1N +NC(=O)N1CCCN(C(=O)c2ccccc2Oc2ccccc2)CC1 +Fc1cccc(-c2cnc(CN3CCOCC3C3CC3)o2)c1 +OC(CNC1CCOc2ccccc21)c1ccc2c(c1)OCO2 +CC(C)c1noc(CCC(=O)NC(C)c2ccncc2)n1 +COC(=O)C(C)NC(=O)Nc1ccccc1Cl +COCc1cccc(C(=O)N2CCCCC2c2nccs2)c1 +O=C(Cc1nc(COc2ccc(Cl)cc2)n[nH]1)NC1CCCC1 +Cc1coc2c1c(C)cc1oc(=O)c(CC(=O)NCCCO)c(C)c12 +CC(=O)Nc1ccc(OC(=O)CCC(=O)c2ccc(C)s2)cc1 +Cc1cc(NC(=O)c2ccccc2SCc2cc(C)no2)ccn1 +O=C(c1ccnc(-n2ccnc2)c1)N1CCCC1C1CCCC1 +COc1ccc(C(=O)N2CCN(c3ncnc4ccccc34)CC2)cc1 +O=C(COCC1CCCO1)N1CCOCC1C1CC1 +CC(C)Oc1ccccc1NC(=O)NCCC(=O)N1CCCCC1 +Cc1ccc(NC(=O)C23CCC(CC2=O)C3(C)C)cc1Cl +Cc1cc(CNC(=O)Nc2ccc3c(c2)COC3)ccc1F +CCOC(=O)CNC(=O)c1cc(C)n(Cc2ccccc2)c1C +CCN1CCN(C(=O)CCc2nc3ccccc3[nH]2)CC1 +O=C(NCc1cc(Cl)cc2c1OCC2)C1CCC1 +CN(C)c1ncc2c(=O)n(CC3CCCO3)ccc2n1 +Cc1ccccc1NC(=O)CNc1ccc(C#N)cc1 +COC(=O)c1ccccc1NC(=O)c1cccc(-n2cnnn2)c1 +CC1CN(c2c(C#N)c(=O)n(C)c(=O)n2C)CCO1 +O=C1Cc2cc(S(=O)(=O)N3CCc4ccccc4C3)ccc2N1 +CC(C)(CNC(=O)c1coc2ccccc12)c1ccncc1 +CCOC(=O)c1nn(-c2ccc(Cl)c(Cl)c2)cc1O +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)Nc1ccc(N(C)C)nc1 +CC(Oc1ccc2c(c1)OCO2)C(=O)Nc1ccccc1F +O=C(CCCn1cncn1)Nc1cc(F)ccc1Oc1ccccc1 +CCOC(=O)c1cccc(NCc2ccncc2)c1 +CC(=O)C(C)CSc1nnc(-c2cccs2)n1C +Cc1nc(C(=O)Nc2ccc(-n3ccnc3C)nc2)cs1 +CCOC(=O)C1=C(CNc2c(F)cccc2F)NC(=O)NC1C +C#Cc1cccc(NC(=O)c2ccc(NC(=O)NC(C)C)cc2)c1 +Cc1ccccc1-c1nc(C(=O)NCCCc2cn[nH]c2C)cs1 +CC(C)NC(=O)CNC(=O)Nc1ccc(F)cc1Br +O=C(NCCc1cccc(O)c1)c1ccc(F)cc1Br +Cc1ccccc1OCC(=O)Nc1nc(-c2ccncc2)cs1 +COc1cc(C(=O)NC(CO)c2ccc(C(F)(F)F)cc2)on1 +Cn1ccc(C(=O)Nc2nc3ccc(F)cc3s2)n1 +CC(C)c1n[nH]c(NC(=O)c2c[nH]nc2-c2ccccc2)n1 +COCCc1noc(COc2ccc(Cl)c3cccnc23)n1 +CCC(C)NC(=O)CN(Cc1ccc(Cl)cc1)S(C)(=O)=O +Cc1oc(NC(=O)CN2CCOC(Cn3cncn3)C2)c(C#N)c1C +COc1ccc(C(C)Nc2ncnc3c2cnn3CCC#N)cc1F +CCc1c(C(=O)Nc2ccn(C)n2)cnn1-c1cccc(Cl)c1 +Cc1ccsc1CN(C)S(=O)(=O)c1cn(C)c(=O)n(C)c1=O +O=C(N=c1[nH]nc2ccccn12)C1CC2CCC1O2 +Cc1cccc(NC(=O)Nc2cccc(CNC(=O)c3ccoc3)c2)c1 +Cc1ccc(NC(=O)Cc2ccc[nH]2)cc1Br +CCCN(Cc1cnc(C(C)C)s1)CC(F)F +Nc1ccc(F)c(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)c1 +COc1cc(CNc2cnns2)cc(OC)c1 +OCc1nnn(CCCOc2ccccc2)c1C1CCCO1 +COC(=O)c1ccccc1Cn1ccc2occc2c1=O +CN(C(=O)CNC(c1ccccc1)c1ccccn1)C1CC1 +COC(=O)C1=C(C(C)C)N(C)C(=O)NC1c1ccc(C)o1 +O=C(C1CC1)N1CCN(C(C(=O)N2CCOCC2)C2CCCC2)CC1 +CC(CCCO)NC(=O)N1CCCC1c1ccc[nH]1 +CC(Cc1ccsc1)NS(=O)(=O)N(C)C1CCCCC1 +CC(C)N1CC(C(=O)Oc2ccc(NC(=O)C3CC3)cc2)CC1=O +CCCCOc1ccccc1NC(=O)N1CCCC(O)C1 +COC(=O)Cc1ccc(NC(=O)c2ccco2)cc1 +Cc1occc1C(=O)OCCN1C(=O)c2ccccc2S1(=O)=O +CNC(=O)C1(NC(=O)c2cncc(Br)c2)CCCCC1 +CCC1CCN(C(=O)c2cccc(OCC(F)F)n2)C1 +O=S(=O)(Cc1ccc(Cl)cc1)N1Cc2cncnc2C1 +O=C1OC(CC(=O)N(Cc2ccccc2F)C2CC2)c2ccccc21 +CCc1onc(C)c1NC(=O)Cc1[nH]c(C(C)=O)c(C)c1C(=O)OC +Cc1nsc(N2CCN(CCC(=O)NC(C)(C)C)CC2)n1 +N#Cc1cccc(C(=O)N(Cc2ccc(C(N)=O)cc2)C2CC2)c1 +CC(=O)Nc1cc(NC(=O)c2c[nH]c3cccc(F)c23)ccc1F +COC(=O)c1cc(Br)cc(C)c1NCC(C)C +CNc1nnc(SCc2ccccc2Cl)s1 +O=C(NCCc1cccc(F)c1)NCC(=O)N1CCCCC1 +Oc1ccc(CCNc2nc3ccccc3o2)cc1 +COc1ccc(N(CC(=O)N2CCCC2)S(C)(=O)=O)c(OC)c1 +O=C(Cc1csc(-c2ccc(O)cc2)n1)N1CCNCC1 +CCOc1cccc(NC(=O)C2CC(=O)N(C)C2)c1 +Cn1ccc(NC(=O)COc2ccc(C(C)(C)C)cc2)n1 +CCC(NC(=O)c1cnc2ccc(C)cn12)c1c(C)noc1C +CCN(C(=O)CC1CCCN(C(=O)NCC(C)C)C1)c1cccnc1 +O=C(Nc1c(F)cccc1F)N1CCC2(CC1)OCCCO2 +O=C(COc1cccc(N2CCCC2=O)c1)Nc1nncs1 +O=C(COc1ccccc1F)Nc1cccc(N2CCCC2=O)c1 +COC(=O)c1ccc2nc(-c3ccc(NC(C)=O)cc3)cn2c1 +Cc1ccccc1C(=O)NCC(=O)N1CCN(c2ncccn2)CC1 +CN(CCOCC1CC1)C(=O)Cc1ccccc1O +Cc1cc(C(=O)COC(=O)c2nccnc2N)c(C)n1C1CC1 +Cc1nn(C)c(NC(=O)c2cccc(OCc3cccnc3)c2)c1C +Cc1nc(CN2CCN(C(=O)c3ccc(C)c(C)c3O)CC2)cs1 +CCCc1[nH]nc(C(=O)N(C)C(C)CC(C)C)c1N +O=C(Nc1ccnn1Cc1cccs1)c1ccc2ncsc2c1 +Cc1ccc(NC(=O)c2cc(Cl)ccn2)c2cccnc12 +CN(Cc1nc2ccccc2s1)C(=O)CCC(=O)c1ccccc1 +CCCCS(=O)(=O)NCC(=O)Nc1ccc2oc(=O)[nH]c2c1 +CC(=CC(=O)OCCNC(=O)c1ccncc1)c1ccncc1 +CC1CCCCC1OCCNC(=O)NCc1nnc2n1CCCCC2 +CCc1onc(C)c1NC(=O)C1(CCOC)CCCC1 +COc1cccc(-c2cc(C(=O)Nc3ccc(F)cc3)n(C)n2)c1 +COCCNC(=O)CN1CCN(c2ccc(Cl)cc2)CC1 +O=C(Nc1ccc(-n2cnc3ccccc32)nc1)c1ccc(F)nc1 +CCc1nc(C)sc1CNC(=O)c1cc(-c2cccn2C)n[nH]1 +CCCn1nnnc1COc1cc(C)ccc1Cl +O=C(Cn1ncc2ccccc2c1=O)Nc1ccccc1C(F)(F)F +Cc1cc(C)n2nc(SC(C)C(=O)N3CC(C)CC(C)C3)nc2n1 +CC(C)n1cnnc1SCC(=O)Nc1cccc2c1CCCC2 +O=S(=O)(N=c1cccc[nH]1)c1ccc(C(F)(F)F)cc1 +Cc1cc2c(cc1Br)OCC(C)C(=O)N2C +COc1ccccc1CNC(=O)Cn1ccc2c(Cl)cccc21 +Cc1noc(C2CCN(C(=O)c3cc(F)cc4[nH]cnc34)CC2)n1 +COC(=O)CSc1ccc2nnc(-c3ccccn3)n2n1 +CCN(CC)C(=O)CSc1nnc(-c2cn(C)nc2OC)n1C +CNC(=O)c1ccc(Nc2c(C#N)nnc3ccc(C)cc23)cc1 +CCOc1ccc(NS(=O)(=O)c2ccccc2)cc1OC +NC(=O)CCCNC(=O)c1ccc(-c2cnco2)cc1 +COc1ccccc1C(C)N(C)S(=O)(=O)c1ccc(C(C)=O)cc1 +CSc1cccc(NC(=O)c2cnc(C)cn2)c1 +CCOC(=O)C(C)NC(=O)c1c(C)cccc1N +CC(C)C(=O)N1CCCC1C(=O)N(C)CCc1ccccc1 +CCC(OC(=O)c1ncn(-c2ccccc2)n1)c1ccc(F)cc1F +Cc1ccc(OS(=O)(=O)c2ccc(C#N)cc2)cc1 +CCOC(C(=O)N1CCn2c(C)nnc2C1)c1ccccc1 +O=C(c1ccco1)N(Cc1ccco1)Cc1c(F)cccc1Cl +Cc1ccc(Br)cc1NC(=O)CNC(=O)c1ccccc1 +Cn1ccc(C(=O)N2CCC3(CC(Oc4ncccc4F)CO3)C2)n1 +Cc1cc(F)ccc1CCNC(=O)c1cccc(-n2cnnn2)c1 +CCOc1ccc(S(=O)(=O)Nc2ccc3[nH]ncc3c2)cc1 +O=C(NCc1nc2ccccc2[nH]1)c1cccc(Cl)c1Cl +CCC(NC(=O)OC(C)(C)C)c1cnn(CC)c1 +Cc1cc(C(=O)NCCNC(=O)c2cccnc2)c(C)n1C1CC1 +O=C(CCc1ccc(F)cc1)N1CCN(Cc2ccncc2)CC1 +CC1CCCCC1CNC(=O)c1cccc(C#N)c1 +Cc1cccc(NC(=O)c2nc(-n3nc(C)cc3C)ccc2Cl)n1 +O=C(c1cc2c(=O)oc3ccccc3c2s1)N1CCOCC1 +CCc1c(CO)nnn1CC(=O)Nc1nnc(COC)s1 +Cc1nc2nc(C)c(C(=O)Nc3ccccc3C)cn2n1 +CCOCC(=O)NCc1ccc(C(=O)OC)cc1 +CCc1ccc(CC)c(C(=O)CSc2nncn2C)c1 +CC(C)N(C(=O)Cn1cccc2cc(C(F)F)nc1-2)C(C)C +COc1ncccc1C(=O)NCCNc1ncccn1 +Cc1cc(NC(=O)NCc2cccs2)ccc1C(=O)N(C)C +CCN(Cc1cccc(F)c1)C(=O)COC(=O)c1nccnc1N +O=c1c2ccccc2c(CO)nn1-c1ccccc1 +CCOc1ccccc1OCC(=O)Nc1c(C)cc(C)nc1C +C=CC(CC(=O)Nc1cc(C2CC2)nc(C)n1)c1ccccc1 +CCC(CC)C(=O)Nc1ccc(OC)c(NC(=O)c2ccco2)c1 +O=c1ccc(C2NCCc3cc(F)c(O)cc32)n[nH]1 +Cc1cc2nc(N3CCCC3C(N)=O)c3ccccc3n2n1 +O=C(NCc1nnc2n1CCCCC2)c1cc(Cl)c2c(c1)OCO2 +COCCN(Cc1ccc(C#N)cc1)Cc1ccc(C#N)o1 +O=C(CC1CSc2nccc(=O)n21)NCC1CCCO1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)N1CCCc2ccccc21 +COc1cc(CO)cc2c1OC(C)C(=O)N2Cc1ccccc1C +COc1ncccc1CNC(=O)N1CCCc2cc(F)ccc21 +CCCCN(CCO)S(=O)(=O)N1CC(C)OC(C)C1 +O=c1ccc(C2NCCc3c(Cl)cccc32)n[nH]1 +CCSc1nc2ncc3c(n2n1)CC(C)CC3=O +O=C(CSc1nnc(-c2cccs2)o1)Nc1ccccc1F +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1ccc(-n2cnnn2)cc1 +Cc1cc(C)n(NC(=O)CCn2nnc(-c3ccccc3)n2)c(=O)c1 +Cn1ccnc1SCC(=O)N1CCc2ccccc2CC1 +CCNC(=O)N1CCc2cc(S(=O)(=O)NC3CCCC3)ccc21 +COc1ccc(Cl)c2c1CCNC2c1cc[nH]n1 +CN(C(=O)NCc1cnn(-c2ccccc2)c1)C1CCCCC1 +Fc1ccc(OCCSc2nncn2-c2ccccc2)cc1 +CCN(C(=O)Cc1csc(NC(=O)C(C)C)n1)C(C)C(C)C +CCC(C)(C)NC(=O)CS(=O)(=O)c1cc(C)ccc1C +Cc1c(CCC(=O)Nc2cnn(CC3CC3)c2)cnn1C +CCN(CC)C(=O)CCC(=O)NCc1cn2cc(Cl)ccc2n1 +CCCc1ccccc1NC(=O)c1ccc(F)c(NC(C)=O)c1 +CC(C)c1ccccc1OCCNC(=O)c1cccnc1 +Cc1ccc(NC(=O)c2ccc(Cn3ccccc3=O)o2)c(O)c1 +O=C(NC1CC2CC1N(C(=O)c1ccccc1)C2)c1cccs1 +CCc1cc(N(C)Cc2nc3cc(Cl)ccc3[nH]2)n2nccc2n1 +Cc1ccc2oc(C(=O)Nc3nnc(-c4ccccn4)s3)cc2n1 +CCn1ncc(CNC(=O)C2(C)Sc3ccccc3NC2=O)c1C +Cc1cc(Cl)c(C(=O)NCCC(N)=O)cc1C +Cc1ccc(OCCCC(=O)N2CCCC(N3CCNC3=O)C2)cc1 +O=C(Nc1ccc(N2CCNC2=O)cc1)NC1CC1 +CCC(=O)Nc1cccc(NC(=O)CCc2ccc(C#N)cc2)c1 +CCc1nc(CC(=O)N2CCN(c3ccccc3F)CC2)cs1 +CCCC1CN(C(=O)CCc2cccc(OC(C)(C)C)n2)CCO1 +Cc1c(NC(=O)CCCNC(=O)c2ccco2)cccc1C(N)=O +CCCOC1CCCN(c2ccc(Cl)c(CO)n2)C1 +CS(=O)c1ccc(C(=O)OCC(C#N)Cc2ccc(F)cc2)cc1 +N#Cc1cc(NC(=O)Cc2ccc(-n3cccn3)cc2)ccc1F +Cc1ccc(C(=O)OCC2COC(C)(C)O2)n1C +COc1cc(C)sc1C(=O)NC(C)c1ccc2c(c1)OCO2 +Cc1nnsc1C(=O)N1CCN(CC(O)c2ccco2)CC1 +Cc1csc(C2CCCN(Cc3cccc(-c4ccncc4)c3)C2)n1 +CN(C(=O)c1ccc(-n2ccnn2)cc1)C1CCc2ccccc2C1 +O=C(Cc1cn2ccsc2n1)NCCc1ccccc1Cl +Cc1c(C(=O)Nc2cnn(C(C)C)c2)nnn1Cc1ccccc1 +Cc1cc(CC(=O)NC(C)c2cccc(C#N)c2)no1 +CCc1ccc(NC(=O)c2cc(C(C)=O)c[nH]2)cc1 +Fc1cc(F)cc(NCc2cnn3ccccc23)c1 +COc1cc(OC)nc(NC(=O)NC2CCCCC2)n1 +CCCCc1noc(C2CCCN(C(=O)c3ccc(OC)cc3)C2)n1 +O=C(NCc1nc2ccccc2s1)c1ccc(-n2cccn2)cc1 +Cc1cccc(NC2=Nc3cc(N)ccc3OC2C)c1C +COc1ccc(OC(C)C(=O)N(C)Cc2ccc(F)c(F)c2)cc1 +CC(O)CNc1nc2c(c(=O)n(Cc3ccccc3)c(=O)n2C)n1C +Cc1cc(Br)ccc1OCc1ncccn1 +Cc1n[nH]c(SCCCOc2ccccc2C)n1 +CCC(C)OC(=O)c1ccc2c(c1)NC(=O)CS2 +O=S(=O)(NCC(O)C1CC1)c1cc(F)ccc1F +Cc1ccc(NC(=O)N2CCCC2c2cc(C)on2)c(C)c1 +COc1ccccc1C(=O)Nc1cccn2nc(C3CCC3)nc12 +Cc1noc(C)c1Cn1c(=O)sc2ccccc21 +CCCc1noc(CCCC(=O)N2CCCC2c2cnn(C)c2)n1 +COc1c(C)cnc(CNC(=O)NCC(OC)c2ccccc2)c1C +CCN(C(=O)CSc1nc2cccnc2[nH]1)c1cccc(C)c1 +O=C(NCc1ccc(O)cc1)c1cc(N2CCCC2=O)ccc1Cl +CC(=O)Nc1ccc(F)c(NCC(=O)N(C)C2CCC(C)CC2)c1 +CCC(CO)NS(=O)(=O)c1ccc(Cl)c(Cl)c1Cl +CC(=O)NCCCNC(=O)N1CCC2(CCCCC2)C1 +Cc1noc(C)c1C(=O)N1CC(C(=O)NCC2CC2)C1 +O=C(C1CCCO1)N1CCCn2nnc(CNc3ncccn3)c2C1 +COc1ccc(CCCN(C)c2ncnc3c2cnn3C)cc1OC +CC1CCN(C(=O)c2ccccn2)c2ccccc2S1 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)NCC(F)(F)F +CCCOc1ccc(CNS(=O)(=O)c2cn[nH]c2)cc1 +CN(Cc1cccs1)C(=O)c1c[nH]c2ccccc12 +COc1c[nH]c(CN2CCCc3ccccc32)cc1=O +O=C1NS(=O)(=O)c2cc(Br)ccc21 +COc1cc(=O)c(C(=O)N2CCOCC2)nn1-c1ccc(C)cc1 +O=C(Cc1c(F)cccc1F)N1CCCC(CN2CCOCC2)C1 +CCc1noc(CN(C)Cc2c(C)nn(-c3ccccc3C)c2C)n1 +N#CC(C(=O)CCCc1ccccc1)c1nc2ccccc2[nH]1 +COc1ccccc1N(CCC(N)=O)C(=O)c1ccc(Cl)cc1 +Cc1cc(NC(=O)c2ccco2)ccc1C(=O)OC(C)(C)C +CCCN(Cc1ccccc1)C(=O)Cc1c(C)nc(C)[nH]c1=O +COCCC(=O)Nc1ccc(Oc2ccccc2)cc1 +N#Cc1ccc(-c2noc(-c3cn(-c4ccccc4Cl)nn3)n2)nc1 +O=C(NCC(O)c1ccsc1)c1ccc2ccccc2c1 +CCCOc1ccc2c(c1)C(c1cnc(C)cn1)NCC2 +Cc1cc(C)c(NC(=O)c2cccc(OCC3CCCO3)c2)c(C)c1 +Fc1ccc(Cn2ncnc2CN2Cc3ccccc3C2)cc1 +COc1ccc2nc(C(=O)NCC(C)(C)c3ccncc3)ccc2c1 +CNC(=O)CN(C)c1cc(N2CCCC2CO)ncn1 +CCOc1cc2c(cc1OC)C(c1cccc(O)c1)NCC2 +Nc1cc(Cl)ccc1C(=O)OCC(=O)NCC1CCCO1 +CCCn1c(NC(=O)c2ccnn2CC)nc2ccccc21 +CCOCC1CCN(C(=O)c2[nH]nc3c2CCCC3)C1 +CCCn1c(SCc2nnc(C)o2)nnc1-c1cccc(C)c1 +COC(C)(C)c1noc(C2CCN(c3ccc4nncn4n3)CC2)n1 +CN(C)C(=O)CSc1nnnn1-c1ccccc1 +CC(C)(CO)NC(=O)NC1CCCc2c1cnn2Cc1ccccc1 +CN(CC1CCCO1)C(=O)Cc1cccc(OCC#N)c1 +Cc1cc(C)nc(NCC(=O)Nc2ccc(Cl)cc2)n1 +CC(=O)c1cccc(S(=O)(=O)N2CCc3sccc3C2)c1 +Cc1cc(C2CCCN2S(=O)(=O)Cc2ccc(F)cc2)no1 +COCc1nc2cc3c(cc2c(C)c1C(=O)OC)OCO3 +COC(=O)CCNC(=O)CSc1cc(Cl)ccc1Cl +COc1ccc(-c2nc3cccc(C#N)n3n2)cc1OC +NC(=O)c1cccc(CNC(=O)Nc2ccc(Br)cc2)c1 +CC(=O)c1ccc(OCc2nnc(Cc3ccccc3)o2)c(C)c1 +O=C(CS(=O)(=O)c1ccc(O)cc1)NC1CC1 +Cc1csc(NC(=O)C(C)Cc2cccc(F)c2)n1 +CS(=O)(=O)NCCCNC(=O)C1C2CC3CC(C2)CC1C3 +C=CCN(CC=C)C(=O)c1cnn(-c2cccc(C(F)(F)F)c2)c1C +COc1ccc(NC(=O)c2ccsc2)cc1OC +CCc1ccc(OC)c(C(=O)CCC(=O)OC)c1 +Cc1ncc(-c2ccccn2)c(CCNC(=O)c2cccnc2)n1 +Cc1noc(C)c1CCC(=O)NC1CC(O)C(CO)C1 +CCC(Nc1ccc(NC(C)=O)cc1)c1ccc2c(c1)OCCO2 +Cc1cnn(CC2CCCN2C(=O)c2ccc(C(N)=O)cn2)c1 +CS(=O)(=O)N1CCC2(CCCN(CC3CCC3)C2=O)C1 +COC(C)c1nc(CSc2cccc(F)c2)cs1 +CCOCCN(C)C(=O)Nc1sc(-c2ccccc2)nc1C +COc1ccc(CNc2ccc(CO)cc2)cc1F +COc1ccc(NC(=O)N2CCCC(OC)C2)cc1OC1CCCC1 +Nc1ccc2c(c1)N(C(=O)Cc1ccccc1Cl)CC2 +O=C(NCCc1cccc(Cl)c1)NCc1ccccn1 +CC(=O)Nc1ccc(O)c(C(=O)C2CCCCC2)c1 +CNC(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O +CCc1nc(CC(=O)Nc2ccc(S(N)(=O)=O)cc2)cs1 +Cc1cccc(C(=O)Nc2ccc(C(=O)N3CCCCC3C)cc2)c1 +CSc1ccccc1NC(=O)c1ccc(S(=O)(=O)N(C)C)o1 +Fc1ccc2c(c1Cl)CCNC2CC1CCOCC1 +CC(C)n1nnc(-c2ccc(C(=O)N=c3[nH]cc[nH]3)cc2)n1 +Cn1c(C(F)(F)F)nn(Cc2ccc(Cl)c(Cl)c2)c1=O +CC(Sc1ccc2c(c1)OCCCO2)c1nc(N)nc(N(C)C)n1 +CCCN(C)C(=O)Nc1ccc(Cl)c(C(N)=O)c1 +CCCOC(=O)c1cc(-c2ccc(C)c(C)c2)nn1CCO +c1cnc(N2CCC(N3CCOCC3)C2Cc2ccncc2)nc1 +CCn1c(SCC(=O)N(C)C)nnc1-c1ccc(Cl)cc1 +CCc1nccn1-c1cncc(C2CCCN(c3cc(C)ncn3)C2)n1 +Cc1ccncc1NC(=O)NCc1ccc(-c2cccnc2)cc1 +CCN(CC)C(=O)c1cnn(-c2ccc(C(F)(F)F)cn2)c1C +N#Cc1ccccc1CNc1ccc(N2CCCC2=O)cc1 +Cc1nn(C)c2[nH]nc(NC(=O)c3ccc(-c4cscn4)cc3)c12 +CC(Oc1cccc(Cl)c1Cl)C(=O)n1ccnc1 +CC(Sc1nnnn1Cc1ccccc1)C(=O)OC(C)(C)C +Cc1cc(C(=O)Nc2cn[nH]c2)c(C)n1Cc1cccs1 +O=C(NCCc1ccc2ccccc2n1)c1cc(Br)c[nH]1 +CC(C)n1ccc(=O)nc1SC1CCN(c2ccccc2F)C1=O +CNc1nc2ccc(S(=O)(=O)CC(C)C)cc2s1 +Cc1ccnn1CC(=O)N1CCN(Cc2ccc(Cl)cc2)CC1 +COc1ccc(CCn2c(C)c(C(C)=O)c(C(C)=O)c2C)cc1OC +Cc1c(CNC(=O)c2cccc(-n3cccn3)n2)oc2ccccc12 +COc1cc(OC)c(C=CCCC(C)(C)O)c(OC)c1 +Cc1nc[nH]c1-c1c(-c2ccccc2)ncn1CCNS(C)(=O)=O +CCOCc1ccccc1CNC(=O)c1cc(C)n(C2CC2)c1C +CN(C)C(=O)c1cccn(Cc2ccc(Cl)cc2)c1=O +CNC(=O)c1ccc(CNCCc2ccccn2)cc1 +O=C(NCc1nnc2n1CCC2)c1ccc(-c2ccc(F)cc2)s1 +Cc1noc(C)c1CN(C)S(=O)(=O)c1cccc(Cl)c1 +Cc1ccc(C(=O)N2CCN(C3=CC=CC4N=CC=C34)CC2)cc1 +Cn1nc(C2CCCCC2)cc1NC(=O)N1CCOCC1C1CC1 +O=C(Cn1ccccc1=O)Nn1cnc2ccccc21 +N#Cc1noc(C(=O)NCCc2ccc(F)cc2)c1N +CCSc1ccc(C(=O)Nc2ccc(C(N)=O)c(Cl)c2)cn1 +Cc1ccc(C(=O)Oc2ccc3cc(C(N)=O)c(=O)oc3c2)cc1C +CCOC(=O)c1nc(-c2ccc3c(c2)OCO3)[nH]c1C +Cc1cccn2cc(CSc3nncc(=O)n3N)nc12 +N#CC(NC(=O)CCOc1ccccc1)c1ccc(Cl)cc1 +Cc1ccc2nc(N3CCOCC3)c3nncn3c2c1 +CS(=O)(=O)c1cccc(NC2CCOCC2)c1 +Cc1cccc(NC(=O)c2cnc3n[nH]nc3c2)c1 +CCOc1cc(F)ccc1NC(=O)c1csc(-c2ncccn2)n1 +Cn1c(=O)n(C)c2cc(CNc3nc[nH]n3)ccc21 +COc1ccc(NC(=O)c2csnn2)cc1NC(C)=O +COCCCC1CCCN(C(=O)c2cc3cc(OC)ccc3n2C)C1 +O=C(c1n[nH]c2c1CCC2)N1CCC(Oc2ccccc2)CC1 +Cn1cnc(CNC(=O)Nc2ccccc2-c2ccccc2)n1 +CC(=O)NCC1CCCN(C(=O)Nc2ccc3nc(C)sc3c2)C1 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccc(C)cc2C)cc1 +CN(C)C(=O)c1cc(NC(=O)c2cccs2)c(=O)n(C)c1 +O=C(COC(=O)c1ccc(F)cc1)NCc1ccccc1F +Cc1cccc(NC(=O)CSc2nnnn2-c2ccc(F)cc2)c1 +C=CCOc1cccc(NC(=O)c2csnn2)c1 +CCOCC1c2c(cnn2CC)CCN1C(=O)CCc1ccccc1 +CC(=O)Nc1ccc(NCc2cnn(-c3ccc(Cl)cc3)c2)cc1 +COC(=O)CCCn1c(C(C)=O)nc2cc(OC)ccc21 +Cc1cnc(C(=O)N2CCN(CC=Cc3ccccc3)CC2)cn1 +Cc1ccc(F)c(OCC(=O)N2CCc3cc(F)ccc3C2)c1 +Cc1sc(-c2ccno2)cc1S(=O)(=O)N(C)Cc1ccccc1 +CC(O)CCNc1ncnc2sc3c(c12)CCC(C)C3 +Cc1nc(OCCNS(=O)(=O)C2CC2)cc(N2CCCCC2)n1 +CC(C)S(=O)(=O)c1noc(C(=O)NC2CCCC2)c1N +O=C(NCCNc1ncccn1)NCC1CCCO1 +CCCC(=O)Nc1ccc(CNC(=O)NC2CCC(C)CC2)cc1 +COc1ccc(C(=O)CSc2nnc(CC(C)O)n2C)cc1 +O=C(Nc1cccc(-c2ccc3nncn3n2)c1)C1CCCO1 +CCS(=O)(=O)N1CCCc2cc(NC(=O)C(C)C)ccc21 +COc1cccc(OC)c1C(=O)NCCC(O)C(C)(C)C +CCOc1ccc(CN(C)C(=O)c2cccc(N(C)C)c2)cc1 +CCOc1ncccc1NC(=O)c1cnc2c(cnn2CC(C)C)c1 +COc1ccc(NC(=O)Nc2ccccc2C(N)=O)c(OC)c1 +CNC(=O)Cn1cc(NCc2cccc(F)c2)cn1 +Cn1nc(C(=O)NC(c2ccc(F)cc2)C2CCCO2)ccc1=O +CC(NC(=O)c1ccco1)C(=O)Nc1ccccc1OC(F)(F)F +Cc1cc(N)cc(C)c1NC(=O)COc1ccc(C(C)(C)C)cc1 +CCCC(C)NC(=O)c1ccc2c(c1)CCC(=O)N2 +Nc1ccc2c(c1)N(CC(=O)N1CCCC1)CCS2 +CN(Cc1coc2ccccc12)C(C(N)=O)c1cccc(F)c1 +Cc1ccc(C#CCCO)cc1N1CCCCC1=O +Cc1cc(C(=O)Nc2cc3c(cc2Br)OCCO3)no1 +CCOCc1ccccc1CNC(=O)Cn1c(C)c(C)sc1=O +CCN1C(=O)C(C)(C)c2cc(S(=O)(=O)N(C)C)cc(C)c21 +O=C(CCNC(=O)c1cccs1)Oc1ccc(C(F)(F)F)cc1 +COC(=O)c1cccc(CSc2nncc(=O)n2N)c1 +Cc1ccc(N)cc1NC(=O)CCOC1CCCCC1 +Cc1occc1C(=O)N1CCN(c2ncnc3c2cnn3C)CC1 +O=C(c1oc2ccccc2c1COc1ccccc1)N1CCOCC1 +C=CCN(CC=C)C(=O)COc1ccc(F)cc1Cl +CN(Cc1cccc(C#N)c1)C(=O)Nc1nncs1 +CCC(CO)N1CCN(S(=O)(=O)Cc2ccccc2C)CC1 +CCOCCNS(=O)(=O)C1=Cc2ccccc2CC1 +CCCn1nnnc1CS(=O)(=O)c1ccc(C)cc1 +Cc1ccsc1C(=O)Nc1ccc2c(c1)sc(=O)n2C +Nc1cc(N)c(OC(F)(F)F)cc1Br +CC(C)(NC(=O)c1cnc(C2CC2)s1)c1cccc(F)c1 +Cc1noc(C)c1C(=O)OC(C(=O)N1CCOCC1)c1ccccc1 +O=C(NCc1ncc(-c2ccccc2)o1)C(O)c1ccccc1Cl +CCn1nccc1CNC(=O)Nc1cccc(C(C)=O)c1 +CC1CCCN(C(=O)Nc2ccn(Cc3ccccc3)n2)C1CO +CC(=O)c1sc(N(CC(C)C)C(C)C)nc1C +CCOC(=O)c1ccc(C(O)CCN2CC(C)OC(C)C2)s1 +O=C1Cc2cc(NC(=O)c3occc3-c3ccccc3)ccc2N1 +CNC(=O)c1ccc(OC)c(NC(=O)CCC=Cc2ccccc2)c1 +CC(C)n1nnnc1-c1cccc(C(=O)N2CCCCCC2)c1 +Cc1noc(C)c1S(=O)(=O)NCCCN1CCc2ccccc21 +CCCNC(=O)Nc1ccc(C(=O)NCCc2ccccc2)cc1 +CC(CCc1ccccc1)NS(=O)(=O)N(C)C(C)C +CC(C)N(C(=O)c1ccc(S(=O)(=O)NCCC#N)cc1)C1CCC1 +CCN1CCN(C(=O)c2nc(-c3oc4ccccc4c3C)no2)CC1 +COc1ccc(F)c(NC(=O)CCc2ccc3c(c2)OCCCO3)c1 +CCNC(=O)c1cccc(CNC(=O)Nc2ccc3c(c2)COC3)c1 +O=C(NC1CC1)c1cc(Cl)ccc1NCc1nnc(C2CC2)o1 +COC(=O)c1ccc(=O)n(CCN2CCOCC2)c1 +COc1ccc(C(O)CN(C)c2ccccc2)cc1N +CCc1nc(C(C)NC(=O)Nc2ccnn2C)cs1 +Cc1ccnc(NC(=O)c2c(C)nn(-c3ccccc3)c2C)c1 +Cc1nnc(SCC(=O)Nc2ccccc2)n1-c1ccccc1 +CCN(Cc1noc(C2CCC2)n1)C(=O)c1cnc2ccccc2c1 +c1cncc(CCNCc2csc(-c3ccsc3)n2)c1 +O=C(Cn1cnc2sccc2c1=O)N1CCC2CCCCC2C1 +Cc1cc(-c2cncnc2)nc(C2CN(S(C)(=O)=O)C2)n1 +Cc1ncc(CN(C)C(=O)C(N)c2ccccc2)s1 +CC(NC(=O)COC(=O)c1ccc2c(c1)OCO2)c1ccccc1 +O=C(Cc1cccc(O)c1)N1CCN(c2nccs2)CC1 +N#Cc1cc(F)ccc1NC(=O)N1CCN(c2nccs2)CC1 +COc1ccc(-c2ccc3c(c2)CCN3)c(OC)c1OC +O=C(Cc1cccnc1)N1CCC(n2ccc(C(F)(F)F)n2)CC1 +CC(CC(=O)NCCc1ccc(Cl)cc1)n1cccn1 +CC(=O)Nc1cc(NC(=O)COc2ccc(Cl)cc2C)ccc1C +O=C(NCCNC(=O)N1CCCN(CC(F)(F)F)CC1)C1CC1 +Cc1ccc(S(=O)(=O)NCCNc2ccc(C#N)cn2)cc1 +COc1ccc(NC(=O)COC(=O)c2cc(F)ccc2F)cc1 +CSc1cccc(NC(=O)Cn2nccc2-c2ccncc2)c1 +COCCN(CC(C)C)S(=O)(=O)c1ccc(F)cc1F +CCOC(=O)CN(C(=O)C1CC(=O)N(C)C1)C(C)C +CCCn1nc(C)c(CN2CCN(C(C)c3cccnc3)CC2)c1C +CCn1ncc(CN2CC3CC(O)CN3CC2C)c1C +Cc1ccc(C(=O)NCc2cccc(C(N)=O)c2)cc1 +CCC(NS(=O)(=O)c1cc(Cl)cnc1N)c1nccs1 +CC(C)c1nc(C2CCCN2C(=O)Cc2c[nH]c3ccccc23)no1 +COc1ccc(CC2NCCc3c(F)cc(O)cc32)cc1 +CCCCS(=O)(=O)NCC(=O)c1c(C)cc(C)cc1C +CCOC(=O)C(NC)c1nc2cc(C)ccc2s1 +Cc1csc(C(C#N)C(=O)c2sc(-c3ccccc3)nc2C)n1 +Cc1cc(C(=O)NC(C)(CNC(=O)OC(C)(C)C)C(C)C)on1 +CC(=O)c1cccc(NC(=O)N2CCC(OCC(C)C)CC2)c1 +O=C(NCCCO)c1cc(-c2cccc(Cl)c2)on1 +O=C1CC2CCC(CN1)N2C(=O)CCc1ccsc1 +CNC(=O)c1ccc(=O)n(Cc2csc(-c3ccccn3)n2)c1 +Cn1nc(CC(=O)NC2CCCCNC2=O)c2ccccc2c1=O +CC(=O)Nc1ccc(SCC(=O)Nc2ccc(Cl)cc2)cc1 +O=C(CCCn1c(=O)oc2ccccc21)NC1CCCCCC1 +CS(=O)(=O)N1CCN(c2cc(Br)ccc2CO)CC1 +CCc1nnc(C(C)N2CCN(C(=O)c3cccc(Cl)c3)CC2)o1 +NC(=O)c1cc(N)cnc1N1CCCC1CCCO +Cc1ccccc1CC1Oc2cc(N)ccc2N(C(C)C)C1=O +CCN(CCn1cccn1)C(=O)C1COc2ccccc2O1 +O=C(CCCOc1ccc2c(c1)CCC(=O)N2)NCc1cccnc1 +COC(=O)c1cccc(NCC(=O)NC2CCCc3ccccc32)c1 +CC(CO)NC(=O)c1ccc(OCC2CCCCC2)cc1 +Cc1nc(CCNC(=O)c2[nH]c3c(c2C)C(=O)CC(C)(C)C3)cs1 +CC(C)CCCC(C)NS(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +Cc1cc(C)c2nc(C)cc(C(=O)NCCn3cnnc3)c2c1 +O=C(N=c1[nH]c2ccccc2[nH]1)c1cnn(-c2cccc(Cl)c2)c1 +COc1ccccc1NCC(=O)c1ccc(F)c(N)c1 +COCc1noc(C(C)Oc2cc(C)ccc2F)n1 +Cc1c(C(=O)N(C)Cc2ccc(Cl)cc2)cnn1-c1ccncc1 +OCC(O)CSc1nnc(NC2CCCCC2)s1 +CC(C)Oc1ccccc1CC(=O)Nc1cnn(CC(F)F)c1 +Cn1c(SCC(=O)Nc2ccccc2F)nnc1C1CC1 +Cc1csc(Cc2nc(-c3c(C)[nH]c4ccccc34)cs2)n1 +NC(=O)c1ccc(CNC(=O)c2cccc(-n3cccn3)n2)o1 +CCCn1nccc1NC(=O)CN1CCN(CC(C)O)C(C)C1 +CCNS(=O)(=O)c1cccc(C(=O)N(C)CC(O)C2CC2)c1 +CC1CCCC(C)N1C(=O)N1CCC(n2cncn2)CC1 +CCN(CC(=O)NC(C)C)C(=O)CSc1ccc(F)cc1 +COc1cncc(C(=O)Nc2ccc(Cl)cc2C)c1 +CC(C)C(CO)NC(=O)NCc1cccc(Cl)c1F +COc1ccc(-n2nnc(C(=O)N(C)c3ccccc3)c2C)cc1 +O=C(CCc1cccnc1)Nc1nc2c(s1)CCC2 +Cc1cc(CNc2ccc3[nH]ccc3c2)c(C)n1C +CCOC(=O)c1cc(-c2cc(Br)ccc2OC)n[nH]1 +Cc1ccc2nc(NC(=O)c3c[nH]c4ccccc4c3=O)sc2c1 +CC(C)c1nnc(NCc2cnc(C3CC3)s2)s1 +NC(=O)C1CCN(C(=O)C2(c3cccc(F)c3)CCCC2)C1 +CCCN(CCC)C(=O)Nc1ccccc1CC(N)=O +CC(C)c1ccccc1OCCNC(=O)NCC1CCOC1 +Cc1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CC(=O)c1cnc(NC(=O)c2c[nH]nc2-c2ccccc2F)s1 +CCOc1ccc(S(=O)(=O)NCc2ccncc2)cc1NC(C)=O +CC(C)c1nc(-c2ccccc2Br)n[nH]1 +CCOCC(C)NC(=O)C1(c2ccc(Br)cc2)CC1 +Cc1cc(Oc2ncccc2C#N)ccc1NC(=O)c1cccnc1C +CN(Cc1ccccn1)C(=O)CNC(=O)N1CCc2ccccc2C1 +O=C(Cc1cnn(-c2ccccc2)c1)NCc1ccccc1F +CCOCCSc1nnc(-c2ccoc2C)o1 +NC(=O)C1CCN(c2ncc(C(=O)N3CCCCC3)cc2Cl)C1 +COc1cc(-c2csc3nc(N)nn23)c(OC)cc1C +CCN1CC(C(=O)NC(c2nccc(C)n2)C2CC2)CC1=O +Cc1c(CCC(=O)Nc2cc(C#N)cn2C(C)(C)C)cnn1C +CCOC(=O)c1ccc2c(c1)N(CC(=O)N1CCCC1)C(=O)CO2 +Cn1ncc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c1-n1cccc1 +Cc1ccncc1NC(=O)NC(C)c1cccc(-n2ccnc2)c1 +CC(=O)Nc1cc(C(=O)N(C)CCc2ccc(F)cc2)ccc1F +CC1CC(NC(=O)c2nc(-c3cnccn3)no2)CC(C)(C)C1 +CC(OC(=O)C1CC1c1cccc(Cl)c1)C(N)=O +FC(F)(F)C1(NCc2ccccc2)CCC2(CC1)OCCO2 +CC(C)c1cc(NC(=O)COC(=O)c2cccs2)on1 +O=C(Nc1cccc(-c2nnco2)c1)C1(c2ccc(F)cc2)CC1 +CCN(CC)C(=O)c1ccccc1NC(=O)N(C)CCC(C)O +O=C(NCc1ccc(N2CCCCC2=O)cc1)c1cccs1 +COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2N)cc1 +Cn1c(=O)c2c(ncn2CCCCCO)n(C)c1=O +CC(OC(=O)c1ccco1)c1nc2ccccc2c(=O)[nH]1 +CC(Nc1ccc(S(C)(=O)=O)cc1N)C(N)=O +COc1ncccc1CNC(=O)CNC(=O)c1ccccc1C +CCNC(=O)CSc1nc2sccc2c(=O)n1C +COc1ccnc(N2CCN(c3ncccc3Cl)CC2)n1 +Cc1cc(OCc2cc(=O)n(C)c(=O)n2C)ccc1Cl +CCC(OC)C(=O)NC(C)c1ccc(NC(N)=O)cc1 +C#Cc1cccc(N(C)Cc2ccc(OCC(=O)NCC)cc2)c1 +CC1CCCN(S(=O)(=O)c2ccnc(N)c2)C1C +COC(=O)CN(C)S(=O)(=O)c1cccc(C#N)c1 +Cc1ccncc1NC(=O)NCC1CCCC(C)C1 +CC(Oc1ccccc1F)C(=O)NC1CCCCC1 +CC(C)COCCC(=O)N(C)C1CCc2ccccc2C1 +Cc1ccc(O)c(NS(=O)(=O)c2cn[nH]c2C)c1 +CC(C)C(NC(=O)Nc1cnn(CC2CCCO2)c1)c1ccccc1 +COC(=O)Nc1ccc(S(=O)(=O)NC(C)=O)cc1 +CCC(=O)N1CCN(c2cccc(Br)c2)C(=O)C1C +COc1ccc(OC(=O)c2cc(C(N)=O)cn2C)cc1 +CC1CC(c2ccc(F)cc2)CN1C(=O)CNC(=O)c1ccsc1 +O=C(CN1CCN(Cc2cscn2)CC1)NC1CCCCCC1 +CCNC(=O)CNC(=O)C1CCCN(C(=O)Nc2cccc(C)c2)C1 +Cc1nc(Nc2ncnc(NC(C)C)c2N)sc1C +Cc1noc(C)c1S(=O)(=O)N(CCCO)C(C)(C)C +CCCOc1cccc(NC(=O)c2[nH]nc(C)c2Br)c1 +CCCCc1nnc(NC(=O)C2CC=CCC2)s1 +Cc1cc(C(=O)Nc2c(C)cccc2-c2nc(C(C)C)no2)no1 +CC(C)NC(=O)CSc1ccccc1C(=O)Nc1nccs1 +O=C(CCc1ccco1)Nc1ccc2nc(N3CCCC3)sc2c1 +O=C(Nc1cccnc1)N1CCC(C(O)C(F)(F)F)CC1 +Cc1ccc(-c2cc(C(=O)Nc3nc[nH]n3)c3ccccc3n2)s1 +CC(C)c1cc(NC(=O)COC(=O)c2cc(Cl)ccc2F)on1 +CC(Sc1nncn1C)C(=O)N(C)C(C)c1ccccc1Cl +O=C(CSc1ncnc2ccccc12)Nc1ccc(F)c(F)c1 +O=C(NC(C1CC1)C1CC1)c1cc(-c2cccs2)n[nH]1 +Cc1sc(=O)n(CC(=O)Nc2cccc3cccnc23)c1C +Cc1nc(C)c(CC(=O)NC(C)c2nc(C(C)(C)C)cs2)c(=O)[nH]1 +Cc1cc(C)c(NC(=O)N(C)Cc2cnn(-c3ccccc3)c2)c(C)c1 +CC1(C)Cc2cccc(OCCNC(=O)CCN3CCOC3=O)c2O1 +CC(=O)Nc1cc(S(=O)(=O)Oc2ccc(F)cc2F)ccc1F +CCOc1ccc(NC(=O)N(C)CC2CC2)cc1C +O=C(N=c1[nH]c2ccccc2[nH]1)c1ccnc2ccccc12 +Cc1cc2c(=O)n(Cc3ccccc3F)cnc2s1 +COC(=O)c1ccc(OC)cc1OC(=O)CC(C)(C)C +CS(=O)(=O)N1CCCc2cc(C(=O)NCC3CCCO3)ccc21 +CC(C)(C)c1cnc(CSc2nnc(C(F)(F)F)n2N)o1 +CN(C(=O)C1CC2CCC1O2)c1ccc(S(C)(=O)=O)cc1 +NC(=O)c1cncc(Oc2ncc(Br)cn2)c1 +Cc1cc(F)ccc1C(=O)N1CCC(Cc2cccc(CO)c2)C1 +NC(=O)c1ccc(NCc2cccc3cccnc23)cc1 +CC(=O)c1ccc(NC(=O)CNc2ccc(F)c(F)c2F)cc1 +CN(C)c1ncncc1NC(=O)N1CC2CCCC2C1 +CC(=Cc1nc(-c2ccc(C#N)cn2)no1)c1cccc(F)c1 +Nc1cc(NC(=O)CSc2ccccn2)ccc1F +COc1ccc2[nH]c(=O)c(CNc3ccc(C)cc3)cc2c1 +O=C(Nc1cc(-c2ccncc2)n[nH]1)c1cc(-c2ccc(F)cc2)on1 +O=C(NCCc1cn2ccccc2n1)c1cc2c(s1)CCC2 +COc1ccc(Cc2nc3ccccc3n2CC(=O)NC2CC2)cc1 +CCCCn1ccc2c(nnc3nc(CC)nn32)c1=O +CN(C)c1nc(NCc2ccccc2)c2cn[nH]c2n1 +CCNC(=O)CN(C)S(=O)(=O)c1ccc(Br)c(C)c1 +NC(=O)C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccccc1 +COCCNS(=O)(=O)c1cc2c(cc1C)NC(=O)CO2 +CC(=O)NC1CCCN(C(=O)Nc2cc(F)cc(F)c2)C1 +CN(Cc1c(F)cccc1Cl)C(=O)CCC#N +COc1ccc2c(c1)OC(n1nnc3ccccc31)C2CO +O=C(CCc1ccc2c(c1)OCO2)N1CCC(n2cncn2)CC1 +COc1cc(C2NCCc3cc(F)ccc32)ccn1 +O=C(Nc1cccc(-n2cnnc2)c1)c1cc(Cl)c[nH]1 +O=C(Nc1nccc2sccc12)c1csnn1 +CCOc1ccccc1C(=O)Nc1sc(NC)nc1C(N)=O +COc1ccccc1Oc1coc2cc(OC(C)=O)ccc2c1=O +O=C(COc1ccc(-c2nnco2)cc1)NCc1ccc(F)cc1 +Cc1ccc(CCC(=O)NCCCn2ccnc2)cc1 +Cc1ccc(CN(C)C(=O)CN2CCOCC2C2CC2)o1 +COc1ccc(C(N)=O)cc1NCCCC(C)(C)C#N +CC(=O)c1cc(C(=O)OC(C)C(=O)N2CCc3ccccc32)n(C)c1 +Cc1noc(C)c1CC(=O)Nc1ccc(NC(=O)c2ccco2)cc1 +Cc1cnc(C(=O)Nc2ccc(C)c(Cl)c2)cn1 +Cc1ccc(N2CCC(CNC(=O)OC(C)(C)C)CC2)nn1 +O=C1NC2=C(C(=O)N(CCO)C2)C(c2cccs2)N1 +CNC(=O)C1CCCN(C(=O)Cc2cccc(OCC#N)c2)C1 +O=C(CC1(O)CCCCC1)N1CCC(OCc2ccc(F)cc2)CC1 +CCC(C)C(=O)NCc1cc(Cl)ccc1OC +CCNc1nnc(-c2cc(C(C)(C)C)nn(CC)c2=O)s1 +Cc1cccc(NC(=O)C(C)Sc2nncn2N)c1C +CCCCCNC(=O)CN1C(=O)CSc2ccccc21 +CCc1cc(NC(=O)c2cnn(CC(C)C)c2C(F)F)[nH]n1 +COc1ccc(Cl)cc1S(=O)(=O)N(C)C(C)C#N +O=C(NCC(F)(F)F)C1(c2cc(-c3ccco3)on2)CC1 +COc1ccc(Cn2nc(C)c(N)c2C)c(OC)c1 +CCOC(=O)c1c(C)[nH]c(C(=O)N(C)Cc2ccsc2)c1C +COc1ccc(C(C)=O)cc1CC(=O)Nc1cc(C)ccc1OC +O=C(C1CCCCN1Cc1cnc2ncccn12)N1CCOCC1 +CC(C)COC1CCN(C(=O)C(C)Cc2ccccc2F)CC1 +Cc1[nH]c2ccccc2c1C1=CCN(C(=O)c2ccc(=O)[nH]c2)CC1 +Cc1csc(C(C)NC(=O)N(C)Cc2nc3ccccc3s2)n1 +O=C(CSc1ncccn1)NCc1ccccc1-c1ccsc1 +NC(=O)C1(Oc2ccc(F)c(F)c2)CCCCC1 +Cc1cc(-n2cccn2)ccc1-c1cn(C(C)c2ccco2)nn1 +CC(C)CCC(=O)N1CCN(C(=O)Nc2ccnn2C(C)C)CC1 +Cc1cc(C)cc(NC(=O)NCCC(=O)N(C)C)c1 +CCc1nn(-c2ccc(CC#N)cc2)c2c1C(=O)CCC2 +Cc1cc(C)cc(C2NC(=O)c3cccc(C)c3N2)c1 +CC(C(=O)Nc1ccc(F)cc1F)n1cc(Br)cn1 +O=C(NCc1ccccc1F)c1cn(-c2ccc(Cl)cc2)nn1 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1cccc(C(C)=O)c1 +Cc1n[nH]cc1NC(=O)c1cnn(-c2ccccc2)n1 +C=Cn1ncc(CN(Cc2ccc(F)cc2)CC2CCCO2)c1C +COc1ccc(CC(O)C(=O)N2CCNCC2)cc1OC +C=CCn1nnc(CO)c1-c1ccc(C(C)(C)C)cc1 +Cc1cc(OCC(=O)Nc2cc3c(cc2Cl)OCCCO3)no1 +COc1ccc(N)cc1CNc1ncnc2[nH]cnc12 +CC(NC(=O)c1ccnc2ccccc12)c1ccc2c(c1)OCCO2 +CC(=O)NC1CC2CCCC(C1)N2S(=O)(=O)c1cccc(F)c1 +NC(=O)c1c(NC(=O)COc2ccc(F)cc2)sc2c1CCC2 +COc1cccc(C(=O)N2CCc3nc(NC(C)=O)sc3C2)c1 +COc1ccc(-c2noc(CCC(=O)Nc3ccc(O)cc3)n2)cc1 +CCC(NC(=O)c1ccon1)c1ccc(Cl)cc1 +Cc1nc2ccc(C(=O)NC(C)c3cnn(C)c3C)cc2nc1C +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc2c(c1)OCCO2 +Cn1ccnc1SCC(=O)Nc1ccc(F)cc1 +Oc1cccc2c1NCc1ccc(C(F)(F)F)nc1N2 +Cc1nc(C)n(CC2CN(CC(=O)Nc3nncs3)CCO2)n1 +CN(CCOCC1CC1)C(=O)C1CC(=O)Nc2ccccc21 +O=C(OCc1csc(-c2ccccn2)n1)c1ccccc1F +Cc1noc(C)c1CC(=O)Nc1cccc2c1ccn2C +CCOC(=O)c1cnn(C2CCCN(C(=O)C3CCCOC3)C2)c1 +CC1=NC2(CCC(C(=O)Nc3cc(C)nn3C)CC2)C(=O)N1C +CCOCCOc1ccc(-c2cc(C(=O)N(C)C)nc(N)n2)cc1 +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1ccccc1 +CC(NC(=O)CNC(=O)OC(C)(C)C)c1cccc(N2CCCC2)c1 +Cn1cccc1C(=O)N1CCC2C1CC(=O)N2CCN1CCOCC1 +CCCCN(C(C)CC)S(=O)(=O)c1cccnc1 +C=CCN(Cc1cccc(C#N)c1)C(=O)c1cc(F)ccc1OC +O=C1N(CC(=O)N2CCc3ccccc32)CCN1c1ccc(F)cc1 +CCOCc1nnc(NC(=O)C2CC3C=CC2O3)s1 +COC(=O)c1c(NC(=O)c2ccccc2C)c(C)nn1C +CC(C)CCC(=O)N1CCCN(CC(F)(F)F)CC1 +Cc1ccc(-c2cc(CO)nn2CCCC(N)=O)cc1 +CC(Cn1cccn1)NC(=O)N(Cc1ccc(O)cc1)C1CC1 +COC(=O)CCC(N)C(=O)c1ccc(OC)c(F)c1 +c1cncc(CSc2nnc3ccc(-c4cccs4)nn23)c1 +CCOC(=O)C(C)NC(=O)C1CC1c1ccc(C(F)(F)F)cc1 +COC(=O)c1cc(OC)ccc1NC(=O)c1ccc(NC(N)=O)cc1 +Cc1cc(C)cc(NC(=O)NCc2nncn2C2CC2)c1 +CC(CC1CCCC1)C(=O)N(C)C(C)c1ccncc1 +O=C(NCc1ccon1)c1coc(COc2ccccc2)n1 +Fc1ccccc1C1c2cccn2CCCN1Cc1ccccn1 +O=C(CCc1ccccc1O)N1CCCC1c1ccsc1 +CCc1cc(-c2ccc(CO)cc2)nc(N(C)C)n1 +Nc1c(S(=O)(=O)c2ccccc2)nnn1CC(O)CO +COc1ccc(-c2c(N)c(C)nn2C)cc1C(C)(C)C +CCc1nc(CN2CCCN(c3ncccc3C#N)CC2)cs1 +COC(=O)C(N)Cc1c[nH]c2cccc(Br)c12 +C=CCN1C(=O)c2ccccc2NC1c1ccccc1OCC +COCc1ccc(CN(C)Cc2nc(C)cs2)cc1 +CC(Nc1cccc(OCc2cscn2)c1)c1ccncc1 +Cc1csc(C2CCCN(Cc3cccc(-c4cccnc4)c3)C2)n1 +COc1ccc(S(=O)(=O)NCCc2nc3ccccc3s2)cc1 +CC(Oc1ccc(F)cc1)c1nnc(SCC(N)=O)n1C +CCc1nc(C)c(C(=O)Nc2cc(C#N)cn2C(C)(C)C)s1 +COc1ccc(-c2nc(CNC(=O)C(C)C)cs2)cc1 +COCCN1CCN(Cc2nc(C)c3ccccc3n2)CC1=O +CCOC(=O)CC1C(=O)NCCN1Cc1ccccc1Cl +N#Cc1ccc(OC(=O)C2CCCN(C(=O)c3cccs3)C2)cc1 +COc1cc(C(C)NC(=O)NC(C)C2CCCO2)ccc1F +CN(Cc1ccncc1)C(=O)Nc1cccc(N2CCCC2=O)c1 +CCc1ccc(C(=O)c2cn(CC(N)=O)c3nc(C)ccc3c2=O)cc1 +CCc1cnc(CNc2cc(C(N)=O)c(F)cc2F)o1 +O=C(Cc1csc(-c2ccoc2)n1)Nc1cccc(F)c1 +O=C1C2CCN(CC2)C1Cc1ccccc1C(F)(F)F +COCCn1cc(NC(=O)NC(C)C(O)c2ccc(F)cc2)cn1 +COCCCCOc1ccc(N(C)C(C)=O)cc1 +C#Cc1cccc(NCC(=O)NCCc2ccccc2OC)c1 +Cc1nnc(N(Cc2ccco2)C(=O)c2ccc(C#N)cc2)s1 +Cc1ccc(NCC2CCN(c3ccc(S(N)(=O)=O)cc3)C2)cc1 +CNC(=O)NCC(=O)Nc1ccc2nc(-c3ccc(F)cc3)oc2c1 +Cc1ncsc1C(=O)NCCNc1cccc(F)c1C#N +CN(Cc1ncnn1C)S(=O)(=O)c1c(F)cccc1Cl +CCn1c(=O)c2c(nc3n2CCN3c2ccccc2)n(C)c1=O +COCCN1CC2(CCCN(C(=O)Cc3cnccn3)C2)CCC1=O +Cn1cccc1C(=O)N1CCCC(c2nnc3ccccn23)C1 +Cc1ccc(NC(=O)c2cnc3onc(C)c3c2)cc1S(C)(=O)=O +Cc1ccc(NC(=O)c2ccoc2C)c(OCC(=O)N(C)C)c1 +CN(c1cccnn1)C1CCN(C(=O)c2ccc3cc[nH]c3c2)CC1 +CN(CCc1cnn(C)c1)C(=O)Cn1c(=O)[nH]c2ccccc21 +CC(OC(=O)c1cccnc1)C(=O)Nc1ccc2c(c1)OCO2 +COc1ccc2ccn(Cc3nc(CCC(C)C)no3)c(=O)c2c1 +COc1cc(-c2noc(-c3ccc(-c4cscn4)cc3)n2)ccn1 +COc1cc(C#N)ccc1OS(=O)(=O)c1cc(F)ccc1F +CC(C)(C)C(C#N)NC(=O)c1cc(F)c(F)cc1Cl +CC(C)n1nccc1NC(=O)c1ccc2[nH]cnc2c1 +CCCn1nc(C(=O)NC(C)c2nc3ccccc3[nH]2)ccc1=O +Cc1ccc(OCC(=O)NCc2cn(-c3ccccc3)nn2)cc1 +COc1ccc(CNC(=O)c2ccc(OC)c(F)c2)cc1F +O=C(NC1CCCc2ccccc21)c1cccnc1-n1cncn1 +O=C(OCC(F)(F)F)c1cnn(-c2ccccc2)c1 +CCCCC(=O)N1CCc2sccc2C1C(=O)OC +O=C(Nc1nnc2n1CCCC2)c1cc(-c2cccnc2)on1 +O=C(NC1CCCN(c2ncccn2)C1)c1scc2c1OCCO2 +Cc1ccccc1Cn1cc(NC(=O)C2CCC2)cn1 +COc1ccc(CN2CCN(C(=O)C3CC3C)CC2)c(OC)c1OC +CC(O)c1cnn(Cc2c(F)cccc2Cl)c1 +COC(=O)c1c(CC(=O)Nc2ccnn2C(C)C)[nH]c(C(C)=O)c1C +COc1cccc(C(=O)OCCc2ccccn2)c1 +Cc1c(CNC(=O)Nc2ccncc2F)cnn1C +CN(Cc1cccs1)C(=O)CNc1ccc(F)c(Cl)c1 +CCC1C(=O)NCCN1Cc1csc(-c2ccc(F)cc2)n1 +CCc1ccc(C(=O)CCC(=O)NCc2csc(=O)[nH]2)cc1 +CC(=O)Nc1ccc(-c2csc(N3CCOCC3)n2)cc1 +C=CCn1c(SCC(=O)NC2CC2)nnc1C1CCCCC1 +O=C(CC1C=CCC1)Nc1ccc2c(c1)OCCO2 +COc1cccc(CNc2ccc(S(C)(=O)=O)nc2)c1OC +CC(=O)OC1=CN(C)S(=O)(=O)c2ccccc21 +COc1ccc(OC)c(NCc2ccccc2C#N)c1 +COc1ccc(-c2cc(C(=O)NCc3ccccn3)sc2C)cc1 +CC=CCOC(=O)CCn1cnc2sc(C)c(C)c2c1=O +Cc1cccc(NC(=O)CSc2nnc(C(C)(C)C)n2N)c1 +CCCn1nccc1C(=O)N1CCC(c2n[nH]c(=O)n2CC)CC1 +Cc1nc(C(=O)N2CCCC(C)C2)nn1-c1ccc(F)cc1 +Cc1cc(C)cc(NC(=O)COC(=O)Cn2cnc3ccccc32)c1 +O=c1[nH]c(CSc2nnc(-c3ccco3)o2)nc2ccccc12 +Cc1cccc(-c2cnc(CNCc3ccccc3F)s2)n1 +COC(=O)C(C)Cn1nc(C(F)(F)F)cc1C1CC1 +Cc1nc(C)c(CNC2(c3cccc(Cl)c3)CC2)s1 +COCc1ccccc1C(=O)N(C)CCC(=O)OC +COc1ccc(CCNC(=O)c2ccco2)c(OC)c1 +O=C(CCCc1ccccn1)N(Cc1ccccn1)C1CCCC1 +NC(=O)NCCCCC(=O)NC1CCC(c2ccccc2)CC1 +CCOc1ccccc1-c1nn2c(=O)c(C)nnc2s1 +Cc1cccc2c1cnn2CCC(=O)NCCCn1cccn1 +CC(C)c1cc(=O)[nH]c2cc(NC(=O)c3ccccc3F)ccc12 +Cc1cc(NC(=O)C(NC(=O)CC(C)C)C(C)C)n(C)n1 +N#Cc1ccc(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)cc1 +Cc1cc(C)n(C(C)CC(=O)NCc2ccco2)n1 +COc1ccccc1C(=O)Nc1cc(F)c(F)cc1N +Fc1ccccc1CSc1ncnc2c1ncn2C1CCCO1 +O=C1C2CCC(C2)N1Cc1cccc(Cl)c1F +CSc1ccc(C(=O)NC(c2ccccc2)c2cccnc2)o1 +Cn1nc(C(=O)NCc2nnc3n2CCCCC3)ccc1=O +CC1Oc2ccc(CO)cc2N(CC(O)CO)C1=O +COc1ccccc1-c1nnc(NC(=O)c2cccc(Cl)c2)o1 +CC(C)C(=O)N1CCC(C(=O)Nc2ccc(F)cc2)CC1 +CCN(CCO)c1ncnc2sc(-c3ccccc3)cc12 +COc1ncccc1NC(=O)Nc1ccc(=O)n(C)c1 +c1cc(-c2nccn2Cc2ccco2)cc(-n2cccn2)c1 +COC(=O)Nc1ccc(CNC(=O)NCCC(C)C)cc1 +C#CCNC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +COc1ncccc1C(=O)NCCOc1ccc(F)cc1 +Cc1ccccc1NC(=O)c1cn2c(n1)CCCC2 +Cc1noc(C2CCCN(C(=O)C3CC(=O)N(C4CC4)C3)C2)n1 +C#Cc1cccc(N(CC)C(=O)c2ccnc(OC3CCC3)c2)c1 +O=C(c1ccc(Cn2ccccc2=O)o1)N(CC1CCOC1)C1CC1 +Cn1nc(C(F)(F)F)cc1C(=O)NCC1CCCO1 +NC(Cc1ccccc1)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +Cc1ccc2c(c1)cc(C(=O)N(C)CC1(C)COC1)n2C +NC(c1ccc(OC2CCCC2)cc1)C(F)(F)F +Cc1occc1-c1nnc(CCC(=O)N2CCC(C(N)=O)CC2)o1 +Cc1c(NC(=O)Cc2cccc(F)c2)c(=O)n(-c2ccccc2)n1C +COC(=O)c1ccc(N2CC(C(=O)OC)CC2=O)cc1Cl +CCC(Oc1ccccc1)C(=O)Nc1cccc(C(=O)NC2CC2)c1 +Cn1ncc(Br)c1C(=O)NC1C2CC3CC(C2)CC1C3 +O=C(N=c1[nH]c2ccccc2s1)C1CC(=O)N(Cc2ccco2)C1 +Cc1nnc(NCCNc2cccc(F)c2C#N)c(C#N)c1C +Cc1nc2nc(SCCS(=O)c3ccccc3)nn2c(C)c1C +Cc1nn(C)c(C)c1C(C)C(=O)N1CCN(Cc2ccco2)CC1 +CCc1ccc2nc3sc(C(N)=O)c(N)c3cc2c1 +C=CCCC1NCCc2cc(Br)c(C)cc21 +CN(CCc1ccncc1)C(=O)CC(C#N)c1ccncc1 +CC(NC(=O)CCCn1cncn1)c1ccc(-c2ccccc2)cc1 +Cc1cc(NC(=O)Cc2ccccc2C(F)(F)F)nc(=O)[nH]1 +CCCC(=O)N1CCC(S(=O)(=O)c2ccccc2)C1 +Cc1cc(C)nc(CN(C)C(=O)c2ccccc2-c2ncc[nH]2)c1 +CNC(=O)c1cc(NC(=O)NC(C)c2cn(C)nc2C)ccc1F +O=C(NC1CCSc2c(F)cccc21)c1cn2cccnc2n1 +CC(NC(=O)C(C)(C)C)c1nc(Cc2ccccc2)no1 +COc1cc(C)c(C(=O)OCC2CCCO2)cc1OC +N#Cc1cc(F)cc(C2NCCc3cc(F)c(O)cc32)c1 +O=C(CCc1ccc(-c2ccccc2F)o1)NC1CCCCNC1=O +CC1CCCCC1NC(=O)c1nnc(Cc2ccc(F)cc2)o1 +Cc1ccc(NC(=O)CNc2ccccc2-n2cccn2)cc1 +Cc1ccc(NC(=O)CNC(=O)c2ccc(N)cc2)c(C)c1 +CC(NC(=O)CSc1ccc(-c2ccccc2)cc1)C(=O)N(C)C +CC(=O)c1ccc(C(=O)Nc2nnc(Cc3ccc(C)c(C)c3)o2)cc1 +NC(=O)c1csc(C(=O)NC2(c3ccccc3)CCCC2)c1 +COc1ccc(-n2ccnc2-c2ccc(CO)o2)cc1OC +Cc1nc2sccn2c(=O)c1NC(=O)NC1CCCCC1 +CCOC(=O)CCC(C)NC(=O)c1ccccc1C +Fc1cccc(-c2cccc(C3CCCN(Cc4ccncc4)C3)n2)c1 +CC(=O)N1CC(C(=O)N2c3ccccc3CC2C)C1 +CCOC(=O)c1ccc(S(=O)(=O)NCc2nc(C)cs2)cc1 +COC(=O)c1ccc(OC(=O)Cc2ccc(F)cc2)cc1 +O=C(Cn1cnnn1)NCCNC(=O)c1ccccc1 +Cc1cccc(NC(=O)COC(=O)c2ccoc2)c1 +CC(NC(=O)CNC(=O)C1CCCCC1)c1cccnc1 +NC(=O)Cc1csc(NC(=O)C2CN(S(=O)(=O)C3CC3)C2)n1 +O=C(NC1CC(=O)N(c2ccccc2)C1)c1cnc2ccccc2n1 +COc1ccc(OCCNC(=O)Cn2ccccc2=O)cc1 +Cc1ccc(S(=O)(=O)N2CCN(c3c(C)n[nH]c3C)CC2)cc1 +CCOC(=O)c1ccccc1NC(=O)Cn1ccnc1 +COc1ccc(CNC(=O)C2CCN(c3ncccn3)CC2)cc1 +COCCCNC(=O)c1ccc2c(c1)CC(C)N2S(C)(=O)=O +CC(=O)Nc1cc(C(=O)COC(=O)c2cccc(F)c2)ccc1O +Cc1[nH]ncc1CCCNC(=O)NC(C(N)=O)c1ccccc1 +C=CCn1nnc(CO)c1COc1c(C)cccc1C +NC(=O)CCN(C(=O)C1CC1c1ccccc1)c1ccc(F)cc1 +COc1cccc(C(NC(=O)CC#N)c2cc(F)ccc2OC)c1 +O=C(CN1CCNc2ccccc21)NCc1ccco1 +O=C(NCC(=O)N1CCc2sccc2C1)Nc1ccccn1 +O=C1CN(C(=O)NCc2cccc(Oc3ccccc3)c2)CCN1 +CN(CC(=O)NCc1cnn(C)c1)c1ccc(Cl)cn1 +N#CCOc1cccc(CC(=O)N2c3ccccc3CC2C(N)=O)c1 +Cc1cc(NC(=O)C(C)S(=O)(=O)c2ccccc2Cl)no1 +Cc1nc(-c2cccc(OCc3nc(C4CC4)no3)c2)no1 +O=C(COc1ccc(F)cc1)c1c[nH]c2ccccc12 +CCN(CC)C(=O)Nc1ccc(S(=O)(=O)N2CCOCC2)cc1 +Cc1c(C(=O)Cn2cc(N)cn2)c2ccccc2n1C +Cc1nn(Cc2ccccc2)c(C)c1CNc1ncccc1C(N)=O +CC1CCC(NC(=O)NCCc2ccnn2C)C(C)C1 +CCCn1nc(C(=O)Oc2ccc3c(C)cc(=O)oc3c2)ccc1=O +Cc1cc(=O)c(C(=O)N2CCN(c3ccccc3)CC2)c[nH]1 +CCC(Nc1nc(C)nc2c1cnn2C)c1nccs1 +CCN(CC(C)C#N)C(=O)c1ccc2[nH]cnc2c1 +Cc1ccc(COC(=O)CNC(=O)Cc2ccccc2)cc1 +CCOC(=O)c1cccc2cnn(-c3cccc(C#N)c3)c12 +CC1Nc2cc(F)ccc2N(CCN2CCOCC2)C1=O +Cc1nnc(SCC(=O)N2CCC(C(N)=O)CC2)s1 +CC(=O)Nc1cc2c(cc1SC(C)C)n(C)c(=O)n2C +CC(C)Nc1ccc(F)cc1NC(=O)Cc1ccc[nH]1 +CCOc1ncccc1CNC(=O)c1cc(OC)c2c(c1)OCCO2 +O=C(NCc1ccc(Cl)cc1)c1cc2ccccc2oc1=O +CC(C)N(C(=O)Cc1coc(-c2cccs2)n1)C1CCC1 +COC(=O)c1ccc(C(=O)N(C)Cc2ccc(SC)cc2)cc1 +COC(=O)Nc1c(C)n(C)n(-c2ccccc2)c1=O +Cn1c(CCNC(=O)Nc2cccc(F)c2)nc2c(F)cccc21 +C=CCN(C(=O)c1cc(NC(C)=O)ccc1F)C1CCCC1 +COc1ccc2c(c1)CCN(C(=O)N=c1[nH]nc(-c3ccco3)[nH]1)C2 +N#CC1CCCN(C(=O)C2(c3ccc(F)cc3)CC2)C1 +COc1cc(NC(=O)c2nn(-c3ccccc3)nc2C)cc(OC)c1 +Cc1ccc(C)c(NC(=O)c2onc(-c3ccccn3)c2N)c1 +Cc1c(C(=O)N2CCc3cnccc32)c(=O)oc2ccccc12 +O=C(NCc1cccs1)C1CC12CCN(C(=O)CC1CCCC1)C2 +Cc1cnc(C(=O)N2CCC3(CC(Oc4cccnc4)CO3)C2)cn1 +CC(=O)c1ccc(NC(=O)NC2CCc3nc(C)nn3C2)cc1C +CC(C(=O)Nc1ccc(-n2cc(CO)nn2)cc1)c1ccsc1 +N#Cc1cccc(C(=O)N2CCCC(C(F)(F)F)C2)c1 +CC(C1CC1)N(Cc1ccccc1)C(=O)c1ccc2c(c1)OCO2 +Cc1nc(C2COCCN2C(=O)c2ccnn2C)cs1 +CCN(CCO)C(=O)c1cnn(Cc2ccccc2Cl)c1 +CC(=CC(=O)OCc1nncn1C1CC1)c1ccc(F)cc1 +C#CCNC(=O)CSc1nccn1Cc1ccccn1 +O=C(Nc1ccccc1NC(=O)c1ccncc1F)c1ccccc1 +O=C(Nc1cccc(OCC(=O)N2CCCC2)c1)c1ccccc1F +CC(=O)N1CCCC1C(=O)Nc1ccccc1SC(C)C +CCCC(C)N(C)S(=O)(=O)c1cccc(-n2cnnn2)c1 +CC(C)N1CCC(NC(=O)c2cccnc2OCC(F)F)C1=O +CC1(C)Oc2cc(NC(=O)C3CCCCC3)ccc2NC1=O +Cc1noc(C)c1CCCNC(=O)NC1CCc2c(O)cccc21 +O=C(Cc1ccon1)N1CC2(CCCC2)c2ccccc21 +Cc1ccc(C2(Cc3ccc4c(c3)OCO4)NC(N)=NC2=O)o1 +O=C(COC(=O)c1ccccc1F)NCCc1ccccc1 +O=C(NCc1ccccn1)c1nnc(Cc2cccc(Cl)c2)o1 +O=C(NCc1ccon1)Nc1c(F)cccc1OCc1ccccc1 +Cc1sc2nc(C(C)C)n3c(SCC(N)=O)nnc3c2c1C +O=C(c1cc(-c2cccnc2)on1)N1CCCCCC1 +CCC(C)NC(=O)c1ccc(-c2ccccc2)nc1N +CCOCc1ccc(CNC(=O)Nc2ccc(F)cc2C#N)cc1 +O=C(c1cccnc1)N1CCCC1c1nc(-c2cccnc2)cc(=O)[nH]1 +CN(C)c1cccc(CNC(=O)Cc2ccc(-n3cnnn3)cc2)c1 +O=S(=O)(NC1CC1)c1ccccc1NCC1CCC1 +Cc1cccc(CCC(=O)Nc2cccc(OCC(=O)N(C)C)c2)c1 +COCCOc1cc(C(=O)N2CCCc3cc(F)cc(F)c32)ccn1 +CC(=O)N1CCCC1C(=O)Nc1ccccc1Oc1cccc(C)c1 +CC(C)Nc1cccc(CNC(=O)CN(C)C(=O)c2cccs2)c1 +CC1CC2CN(C(=O)c3nn(C)c4ccccc34)CCC2O1 +Brc1cnc2c(cnn2Cc2ccsc2)c1 +CCN(C(=O)C1CCN(c2cnccn2)CC1)c1ccc(F)cc1 +N#Cc1nnn(-c2ccc(Br)cc2)c1C1CCC1 +COc1ccc(NC(=O)N2CCCC2c2ccncc2)c2cccnc12 +CNC(=O)c1sc(-c2ccc(Cl)cc2)nc1C +O=C(Nc1ccccc1Oc1ccccc1)c1ccccn1 +CC(C1CC1)N(C1CC1)S(=O)(=O)c1ccc(N2CCCC2=O)cc1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)C(C)(C)C +CC(C)CCNC(=O)Cn1nc2c(cc1=O)CCCCC2 +CCN(Cc1ccncc1)C(=O)c1cc(Cl)ccn1 +O=C(CC1CSc2nc3c(c(=O)n21)CCC3)Nc1ccncc1 +COc1cccc(-c2cnc(N)nc2C2CCCN2C(C)=O)c1 +CC(C)CC(O)C1CCN(C(=O)c2cc(F)cc(C#N)c2)CC1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NCCc1ccccn1 +CCOC(=O)CNC(=O)CN1CCN(c2ccc3c(c2)OCO3)C1=O +COc1cc(F)ccc1NC(=O)NCCC(=O)NCc1ccncc1 +N#Cc1ccc(OC(F)F)c(NC(=O)NCCN2CCOCC2)c1 +Cc1cnc(NC(C2CC2)C2CC2)nc1-c1cnn(C)c1 +O=C(NCCOc1ccccc1F)C1CCC(=O)N(C2CC2)C1 +O=C(CCn1ncc2ccccc21)Nc1cccnc1 +COc1ccc(O)c(C(=O)OCC(=O)NC(C)C)c1 +Cc1n[nH]cc1CNS(=O)(=O)c1cccc(Br)c1 +CCN(CC1CCOC1)C(=O)CCn1c(=O)oc2ccccc21 +CCCc1noc(CCCC(=O)N=c2[nH]nc3cc(C)ccn23)n1 +CCCCC(Nn1cncn1)c1ccc(F)cc1F +COc1cc(C)ccc1OS(=O)(=O)c1cccs1 +O=C1c2ccccc2C2N1CCCN2S(=O)(=O)c1ccccc1 +CC1CN(S(=O)(=O)N(C)Cc2nc3ccccc3[nH]2)CC(C)O1 +CCCOC(=O)c1nnn(-c2ccc(Br)cc2)c1C +Cc1cc2c(cc1Br)C(C)(O)OC2(C)C +CCc1onc(C)c1NC(=O)NC1CC(C)(C)OC1(C)C +Cc1cc(C(=O)N2CCCC2)ccc1NC(=O)N1CCOCC1 +O=C(c1ccncc1)c1cccc(C2OCCO2)c1 +CC1CN(C(=O)c2cccnc2OCC(F)F)C(C)CO1 +CC#CCN(CC1CCCO1)S(=O)(=O)c1ccc(C#N)cc1 +COCCNC(=O)c1ccc(NCc2cnn(C)c2)nc1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)OCC(=O)N1CCCC1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1cccc2cn[nH]c12 +CC(c1ccc(C#N)cc1)N1CCOC(CN(C)c2cccnn2)C1 +CC(=O)N1CCC(C(=O)N2CCN(CCn3cccn3)CC2)CC1 +COc1ccccc1C(C)Nc1cccc(N(C)C(C)=O)c1 +Cc1cc(C(=O)Nc2ncccc2C)c2cnn(C(C)C)c2n1 +CCn1cc(Cl)c(-c2nc(C3CC3)nn2-c2ccccn2)n1 +Cc1cccc(CC(=O)Nc2nnc(Cc3ccccc3)o2)c1 +Cc1n[nH]c(C)c1CCC(=O)NCCc1ccc(-n2cccn2)cc1 +Cc1cccc(NC(=O)C2CN(C(=O)c3ccc(F)c(F)c3)C2)n1 +CCCCc1nc(CS(=O)(=O)c2ccc(O)cc2)no1 +CS(=O)(=O)N1CCN(C(=O)CCn2cccn2)CC1 +O=C(COc1ccc(Br)cc1)Nc1ccccc1O +COc1ccc(CN2C(=O)c3cccnc3C2O)cc1 +Cc1ccccc1C(=O)c1cnn(-c2ccccc2)c1N +CC(C)c1ncc(CN2CCOC(c3ccc(Cl)cc3)C2)cn1 +N#CCCSc1nnc(-c2ccccc2F)n1-c1ccccc1 +CC(C)NC(=O)Nc1cccc(C(=O)Nc2ccccc2)c1 +O=S(=O)(Oc1cccc2cccnc12)c1cccc(F)c1 +COC(=O)CCN(C(=O)Cc1ccc(F)c(F)c1)C1CCOCC1 +CCc1nc2ccccc2n1CC(O)COCc1ccco1 +CC1=C(C(=O)OC(C)C)C(c2cn(C)nc2C)n2ncnc2N1 +CCCCOc1ccc(-c2cc(CO)c(=O)n(CC)n2)cc1 +Cc1ccc(=O)n(CCc2cc(Cl)c3c(c2)OCCCO3)n1 +CCC(C(=O)Nc1ccc(N2CCOCC2)nc1)c1ccccc1 +CC(c1ccc(S(N)(=O)=O)cc1)N(C)CCc1ccncc1 +CC(C)(C)OC(=O)Nc1ccc(Br)cn1 +CC(C)n1nccc1NC(=O)CSc1nnc(C2CC2)n1C1CC1 +CCn1cc(-c2c(C)c(-c3ccc(C)o3)nc(N)c2C#N)cn1 +CN(C(=O)CC1CCCCC1)c1ccccc1S(C)(=O)=O +Cc1ccccc1NC(=O)CSc1nncn1C(C)C +CC(C)C1COC(=O)N1Cc1noc(-c2ccccc2)n1 +Cc1cc(NC(CC(C)C)c2ncnn2C)n2nccc2n1 +O=C(NC1CNCc2cc(Cl)ccc21)C1CC1 +Cc1cc2nc(Cn3nnc4ccccc43)[nH]c2cc1C +O=C(NCCCOc1ccccc1F)C1Cc2ccccc2O1 +O=c1c2ccccc2c(=O)n2n1Cc1ccccc1C2 +CCC(C)c1ccc(NC(=O)NCc2ccncc2)cc1 +Cc1cc(C(C)NC(=O)CCc2c(C)nn(C)c2C)c(C)s1 +COCC(C)NC(=O)N(C)C(C)c1ccc(S(C)(=O)=O)cc1 +CN(C(=O)Cc1ccccc1)C(C#N)c1ccncc1 +CC1(C(=O)NCCc2ccccn2)Oc2ccc(Cl)cc2NC1=O +N#CCCN1CCN(Cc2cccc3ccccc23)CC1 +Cc1cc(C)n(CCC(=O)NC2CCc3nnc(C(C)C)n3C2)n1 +Cc1noc(C)c1CNC(=O)N(Cc1cccc(F)c1)C1CC1 +COCCn1nc(C(=O)NCCc2cccs2)ccc1=O +CCOCc1ccc(CNC(=O)c2cccc(C)c2)cc1 +O=C(CSc1nnc(-c2ccccc2)o1)Nn1cn[nH]c1=O +COc1ccc2c(=O)cc(C(=O)NCCCO)oc2c1 +CCc1nc(CNc2ccccc2Oc2ncccc2C#N)cs1 +O=C(Cc1ccc[nH]1)N1CCN(c2cnccn2)CC1 +Cc1cc(CNC(=O)c2nc(S(C)(=O)=O)n3ccccc23)c(C)o1 +O=C(Nc1ncn(Cc2ccccn2)n1)c1ccccc1OCC1CC1 +CC(C)c1nnc2sc(C(N)c3ccccc3)nn12 +Cn1cc(Br)cc1C(=O)N(CC(F)(F)F)C1CC1 +CN(C)Cc1c(O)c(=O)cc(CO)n1C1CCCCC1 +Cc1cc(C)c(C(=O)NC(C)c2cccc(N3CCCC3)c2)c(=O)[nH]1 +O=C1CN(C(=O)CNc2ccccc2-n2cccn2)CCN1 +Cc1nn2c(CNC(=O)c3ccc4cc[nH]c4c3)c(C)nc2s1 +CC1CCc2nc(CN3CCCC3CN3CCOCC3)sc2C1 +CCOC(=O)CN(C)Cc1cc(F)ccc1Br +Cc1nn(Cc2cccc(F)c2)c(C)c1NC(=O)C1CCCC1 +COc1ccc(NC(C)=O)c(NCc2cn3c(C)cc(C)nc3n2)c1 +CCCCNS(=O)(=O)c1ccc(C)cc1C#CCO +COc1ccc(-c2cncc(C(=O)NCC3CC3)c2)cc1OC +Cc1nc(CNC(=O)c2cc(-c3ccncc3)c3cnccc3n2)no1 +O=C(Nc1ccc[nH]c1=O)c1ccc(S(=O)(=O)C(F)F)cc1 +CC(=O)c1ccc(C(=O)N(C(C)C)C2CCC2)cc1 +Cc1noc(C)c1CN1C(=O)C(C)Oc2ccc(N)cc21 +C=C(C)C1NCCc2cc(OCC)c(O)c(Cl)c21 +O=C(CC(F)(F)F)N1CCN(CC2=Cc3ccccc3OC2)CC1 +CN(C)C(=O)c1ccc(Cl)cc1NCC1CCOC1 +COC(=O)CCC1CCN(C(=O)Nc2nc(C)ns2)CC1 +Cc1cnc(-n2nnc(C(=O)NCC(N)=O)c2C)s1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cccc(S(C)(=O)=O)c1 +COCCNC(=O)C(C)N1CCSc2ccc(N)cc21 +O=c1cc(CNc2ccc(Cl)c(Cl)c2)[nH]c(=O)[nH]1 +O=C(NCc1ccccc1OC1CCC1)N1CCOCC1C1CC1 +COc1ccc(C)cc1C(=O)N(CCCO)C(C)C +O=C(Nc1ccc(Oc2cnccn2)cc1)c1cc(Cl)ccn1 +O=C(NCc1ccc(C2OCCO2)cc1)Nc1ccncc1 +CNC(=O)c1ccc(CNC(=O)c2cc3ccccc3c(OC)n2)cc1 +O=C(NC1CCCNC1=O)c1cccn1Cc1cccs1 +CCCC(NC(N)=O)C(=O)Nc1ccc(OC(C)C)cc1 +Nn1c(SCc2cc(=O)n3ccsc3n2)nnc1-c1ccco1 +O=C1C2CCCN2C(=O)CN1Cc1cc(F)ccc1C(F)(F)F +CC(C)NC(=O)N1CC2CN(Cc3cccc(F)c3)C(=O)C2C1 +O=C(COc1ccc(Cl)cc1)Nc1ccc2[nH]c(=O)c(=O)[nH]c2c1 +O=C(NCCCn1ncc2c(Cl)cccc21)C1CCC1 +Cc1cc(S(C)(=O)=O)ccc1NC(=O)COC1CCCCC1 +N#Cc1nncn1CC(=O)Nc1sc2c(c1C(N)=O)CCCC2 +CCN(Cc1ccco1)C(=O)NCc1ccc2c(c1)OCO2 +O=C(CCCOc1ccc(Cl)cc1Cl)NC1CC1 +CC(NC(=O)Nc1ccnn1C(C)C)c1ccc(-c2cccnc2)cc1 +Nc1cccc(N2CCN(C(=O)c3ccccc3F)CC2)c1 +CCOC(=O)Cc1csc(NC(=O)c2ccc(N)nn2)n1 +Cc1cc(=O)n(C)cc1NC(=O)c1cn(C)nc1C(C)(C)C +COC(=O)C1=C(C)Nc2nnnn2C1c1cccc(C)c1 +CCn1ncc(C(=O)N2CCN(CCOC)C(=O)C2)c1C(F)(F)F +CCn1c(=O)[nH]c(=O)c2cc(C(=O)Nc3ccc(C)cc3)c(C)nc21 +CC(=O)Nc1ccc(C(C)=O)cc1OCC(=O)NC(C)(C)C +O=C(Nc1ccc2c(c1)COC2=O)NC1CC2C(=O)NCC(=O)N2C1 +COc1cc(F)ccc1NC(=O)c1ccc(N2CCCC2)nc1 +CCC(C)NC(=O)c1cccc(CNC(=O)CNC(N)=O)c1 +NC(=O)C1CN(C(=O)NCc2cn3cc(Cl)ccc3n2)CCO1 +O=C(CNC(=O)c1ccnc2ncccc12)NCc1ccc(F)cc1 +COCCCC(=O)NCC(C)(C)c1ccncc1 +Cn1c(=O)n(CC(=O)NCC2CCOC2)c2ccccc21 +O=C(Cn1ccnc1)NCC1COc2ccccc2O1 +Cc1cccc2c1CCN2C(=O)c1cccnc1OCC(F)F +OCc1cn(CC2CCCN(c3nc4ccccc4o3)C2)nn1 +Cc1c(Br)cccc1COC(=O)C1CNC(=O)C1 +Cc1ccccc1CNc1nc(CCCN2CCOCC2)cc(=O)[nH]1 +Cc1nnc(SCC(=O)NC(C)C)n1C1CCCCC1 +Cc1nn(C)c(C)c1OS(=O)(=O)c1ccc(CC#N)cc1 +CC(=O)c1cccc(NC(=O)N2CCCC2CC(O)c2ccco2)c1 +CCOc1ccc(C(=O)NCCc2ccc(O)cc2)cc1 +COc1ccc(-c2noc(C(C)NC(=O)c3cccnc3)n2)cc1 +CS(=O)(=O)NCc1ccc(-c2nc(-c3ccc(C#N)cn3)no2)o1 +NC(=O)COc1cccc(COC(=O)c2cscn2)c1 +CC(C)CCNC(=O)COc1cccc2c1OC(C)(C)C2 +O=C(Nc1cccnc1)c1ccc2c(c1)nnn2Cc1ccc(F)cc1 +CCOc1ccc(-n2nnnc2SCC(=O)c2ccccc2)cc1 +CC(C(=O)Nc1cccc(C#N)c1)N1CCc2cc(F)ccc2C1 +Cc1ccc(NS(=O)(=O)c2ccccc2)cc1S(N)(=O)=O +CC(C)OC(=O)CS(=O)c1ccc(S(C)(=O)=O)cc1 +CN(C(=O)c1ncn(-c2ccccc2)n1)c1cc(F)ccc1F +CCOc1ccccc1CNC(=O)c1cc2ccccc2[nH]1 +CC(C)CC(NC(=O)Nc1nccs1)C(=O)N(C)C +COC(=O)c1cccc(NC(=O)C2(C)Cc3ccccc3C(=O)O2)c1 +CCc1nc(C)sc1Cn1ccnc1-c1ccc(C#CCO)s1 +CC(C)NC(=O)c1nc2nc(-c3ccccc3)cc(C(F)(F)F)n2n1 +COC(=O)CCCS(=O)(=O)N1CCOCC1C +CN(Cc1nccn1C(F)F)C(=O)CNC(=O)CC(C)(C)C +Cc1cnc(-c2ccc(F)c(Br)c2)o1 +Cc1ccccc1CNC(=O)C1c2ccccc2CC(=O)N1C(C)C +COCC(=O)N1Cc2cc(Cl)ccc2CC1c1ccccc1 +Cc1c(-c2ccnc(C(C)C)n2)nnc2nc(-c3cccnc3)nn12 +COc1ccc(-c2nc(-c3ccncc3)no2)cc1 +O=C1CCCN1CCC1CCCCN1C(=O)c1cccnn1 +COc1ccc(C(=O)N2CCOCC2)cc1NC(=O)c1ccccc1 +Cc1ccc2ncc(C(=O)N(C)CCOCc3ccccc3)n2c1 +CN(c1c(F)cccc1F)S(=O)(=O)c1ccccc1F +Cc1ncc(CN(C)CCn2c(C)csc2=O)s1 +CN1C(=O)C(O)(CC(=O)c2ccccc2Cl)c2ccccc21 +O=C(NCCNC(=O)c1n[nH]c2c(Cl)cccc12)c1ccsc1 +CC(C)Cn1nnc(C(=O)OC2CCCCC2)c1N +COCC1c2c(cnn2C)CCN1S(=O)(=O)c1cccc(C)c1 +Cc1ccc(C(=O)NCc2csc(=O)[nH]2)c(Br)c1 +N#Cc1cc(Cl)ccc1NCc1ccc(-n2ccnc2)nc1 +CC(CC1CCCC1)C(=O)N=c1[nH]nc2ccccn12 +Cc1ccc(-c2nc(C(=O)NC(C)c3ccc(F)cc3)no2)cc1 +CC(=O)Nc1ccc(OS(=O)(=O)c2c(C)cc(C)cc2C)cc1 +CCc1ccc(C(=O)N2CCN(S(=O)(=O)c3cccnc3)CC2)o1 +Cc1c(C(=O)N2CC(C)C(N3CCOCC3)C2)oc2ccc(F)cc12 +CCCn1cc(-c2ccnc(NCCN3CCCCC3=O)n2)c(C)n1 +CS(=O)(=O)c1cccc(OC(=O)c2ccc(-n3cncn3)cc2)c1 +C=CCOCC1CN(C(=O)c2cccnc2OC)Cc2nnn(C)c21 +CCOC(=O)Cn1ccc(=O)c2c(Cl)ccc(OC)c21 +O=C(Nc1ccc(Oc2cccnc2)nc1)c1cc[nH]c(=O)c1 +C#CCN(C(=O)NCCc1ccccn1)C1CCc2ccccc21 +CC(C)(C)Oc1cc(CNC(=O)NCc2ccc(O)cc2)ccn1 +COc1cccc(NC(=O)N2CCN(c3cccc(O)c3)CC2)c1 +CCNC(=O)c1cccc(CNC(=O)c2cccc(COC)c2)c1 +CN(C(=O)c1ccc(S(C)(=O)=O)cc1)C1C2CC3CC(C2)CC1C3 +CCOC(=O)c1cnc(OC)nc1-c1ccccc1F +CCOC(=O)CNC(=O)N1CC2CC3CC(C2)CC1C3 +CCOc1cc(NC(=O)c2cccs2)c(OCC)cc1NC(C)=O +O=C(c1cscn1)N1CCC(Cc2ccc3ncccc3c2)C1 +COc1ccc(OCCN(C)C(=O)NC(C)c2ccncc2)cc1 +CCN(CC)C(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +CNC(=O)CCNS(=O)(=O)c1ccccc1Br +O=C(Nc1nc2ccc(F)cn2n1)c1ccc(-n2cccc2)c(F)c1 +CCN(CCO)C(=O)NCCc1cc(F)cc2c1OCOC2 +CS(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2F)cn1 +CC(=O)c1cccc(NC(=O)Nc2cccc(C(C)=O)c2)c1 +CCc1nnc2n1CCN(C(=O)c1cc(C)sc1C)C2 +CC(=O)c1csc(NC(=O)Cc2ccc(C(F)(F)F)cc2)n1 +Cc1cnc(C(=O)NCc2ccc(Oc3ccc(F)cc3)cc2)cn1 +O=S(=O)(NCc1nnc2n1CCCCC2)c1c(F)cccc1F +CCOc1ccc(-c2cc(=O)[nH]c(CC)n2)cc1N +COc1ccc(-c2csc3ncnc(SCCC#N)c23)cc1 +COc1ccc(Cl)cc1CNC(=O)c1nc2ccccc2c(=O)[nH]1 +N#Cc1cccc(N2CC3CCC(C2)N(Cc2cscn2)C3=O)n1 +Cc1cc(C)n2nc(C(=O)Nc3ccc(Cl)cc3C)nc2n1 +O=C1C(Cc2ccccc2F)Oc2cc(O)ccc2N1CCO +N#Cc1cccc(S(=O)(=O)Nc2ccc(F)cc2Cl)c1 +Cc1ccc(C(CN2CCOCC2)NC(=O)Nc2ccccc2)cc1 +Cc1ccc(NC(=O)CCNS(=O)(=O)c2cccnc2)cc1 +O=C(CSc1ncnc2c1oc1ccccc12)N1CCCCC1 +Cc1ccccc1C1CN(Cc2cn(C)nc2-c2cccnc2)CCO1 +O=S(=O)(c1ccc2c(c1)OCCO2)N(Cc1ccccn1)C1CC1 +NC(=O)c1ccccc1NC(=O)C1CC(=O)N(C2CCCC2)C1 +O=C(Nc1cccc(OC(F)(F)F)c1)c1cscn1 +O=C(NCc1cc(F)cc(C(F)(F)F)c1)c1cnn2c1SCC2 +COC(=O)c1ccc(CCC(=O)N(C(C)C)C2CCC2)cc1 +CCOC(C)c1nccn1Cc1ccn(-c2ccccc2)n1 +CCc1nc(CN2CCCC(c3cc(C(N)=O)[nH]n3)C2)no1 +Cc1nc2ccccc2nc1SC(C)C(=O)N(C)CCC#N +CNC(=O)c1ccc(CNCC(=O)Nc2cc(C)ccc2F)cc1 +Cc1cc(O)cc(-c2cccc(S(=O)(=O)N3CCCC3)c2)c1 +CCCS(=O)(=O)N1CCCN(C(=O)c2ccsc2)CC1 +CCC(=O)N1CCCC(C(=O)NC2CCC(CC)CC2)C1 +Cc1ccc(O)c(S(=O)(=O)Nc2ccccc2Cn2cccn2)c1 +c1ccc2oc(NC3=NCN(C4CC4)CN3)nc2c1 +CC(=O)NC(CC(=O)NC1CCCC1)c1ccc(Cl)cc1 +COc1ccccc1CC(=O)NCC1CCCN1c1cccnn1 +CN(C)c1ncc(C(=O)NCCc2nc3ccccc3n2C)cn1 +Cc1cc(C)n(CCCNC(=O)c2ccccc2C)n1 +CCCc1nc(N(C)Cc2nc(CC(C)C)no2)c2cnn(C)c2n1 +O=C(CCc1cccnc1)N1CCC(CO)C(O)C1 +COc1ccc2nnc(CCC(=O)N3CCCCCC3)n2n1 +Cc1nn(C)c(C)c1CC(C)C(=O)Nc1cnccn1 +O=C(NC(CCO)c1cccs1)c1coc2ccccc12 +Cc1nccc(C(=O)N(C)C2CCN(c3ccc(Cl)cc3)CC2)n1 +COc1cccc(OC)c1C(=O)Nc1c(F)c(F)c(F)c(F)c1F +COC(=O)C(c1ccccc1Cl)N1CCC(C(N)=O)CC1 +Cc1occc1C(=O)N1CCC2(CC(=O)N(c3cccc(C#N)c3)C2)C1 +C=CCNc1ncnc(Nc2cc(F)ccc2F)c1N +Cc1cc2c(cc1Br)CCNC2CO +Cc1c(NC(=O)c2cccs2)cccc1C(=O)NCC(C)C +COc1ccc(C)cc1S(=O)(=O)NCC(OC)c1ccsc1 +CCCC(=O)N(CC1CCCO1)c1nc2c(OC)cccc2s1 +COC(=O)C1(NS(=O)(=O)c2cn[nH]c2)CCCC1 +CC(NC(=O)c1cccc(Cl)c1)c1ccc(N)cc1 +CC(=O)N1CCCN(c2c(N)c(C)nn2C)CC1 +CC(=O)N1CCC(CCc2nc(-c3cc4ccccc4o3)no2)CC1 +Cc1nc2ccc(NC(=O)c3nccnc3N)cc2o1 +COc1cc(CC(=O)Nc2ccc(F)cc2)cc(OC)c1OC +CC(C)CN(C)C(=O)c1csc(-c2ncccn2)n1 +CCNC(=O)C(C)NC(=O)CCSc1ccccc1F +O=C(NCCOc1ccccc1)c1cc2n(n1)CCS2 +CC1CCN(S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)CC1 +COc1ccc(-c2nnc(Cc3nc(C)no3)o2)cc1 +CCC(C(N)=O)N1CCC(N(Cc2nnc(C3CC3)n2C)C(C)=O)C1 +CCCCNC(=O)C1CC(=O)N(C(C)c2ccccc2)C1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(C(=O)NC(C)C)cc1 +CC(=O)c1ccc(S(=O)(=O)N(Cc2ccsc2)C2CC2)cc1 +CCN(CCCNC(=O)NC1CC1)c1ccccc1 +COc1ccc(CC2CCCN2C(=O)NC(C)c2nncn2C)cc1 +Cc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1C(N)=O +CCC(=O)Nc1ccc(NCc2cccn2C)cc1 +CC(=O)Nc1ccc(CC(=O)NCc2ccncc2)cc1 +C=CCNC(=O)c1ccccc1NC(=O)c1ccc(F)cc1 +CCN1CC(C(=O)N2CCC(C(=O)N3CCCCCC3)CC2)CC1=O +COc1ccc2c(ccn2CCC(=O)Nc2ccc(O)cc2)c1 +Cc1occc1-c1nnc(SCc2ccc(F)c(F)c2)n1N +CC(C(=O)Nc1cc(F)ccc1F)n1cc(Br)cn1 +O=C(NCCn1cnc(C2CCCC2)cc1=O)c1cccc(Cl)c1 +CCn1c(SCC(=O)N2CCc3ccccc32)nnc1C(C)C +CCc1nc(NC(=O)NC(c2ccccc2)c2ccccc2)nn1C +CCCNC(=O)C(C)Nc1nc2ccccc2s1 +Cc1nn2ncc(C(=O)NCC3CCCCC3)c2[nH]1 +COC(=O)NCC(=O)NC(C)c1c(C)noc1C +Cc1cccc(C(=O)N(Cc2c(F)cccc2Cl)C2CC2)n1 +CC(C#N)N1CCN(CCOc2ccccc2)CC1 +CCOC(=O)c1cc(-c2c(C)cc(OC)cc2C)n[nH]1 +O=C1CSc2ccc(C(=O)Nc3cc(F)ccc3Cl)cc2N1 +CC(NC(=O)c1ccco1)c1ccc(OC(F)F)cc1 +COc1cc(N)cc(CCC(=O)N(C)C)c1OC +O=C(c1cccnc1)N1CCCC1c1nnc2n1CCCCC2 +CCc1ccc(CN(C)C(=O)c2cccc(C#N)c2)cc1 +CCc1nc2nc(C)cc(N3CCN(c4ccccc4)CC3)n2n1 +Cc1noc(C)c1S(=O)(=O)NC1CCN(c2nccs2)CC1 +CCNC(=O)c1cccc(NCC(=O)Nc2ccccc2C(N)=O)c1 +Cc1cc(C)n(CC(C)Nc2nccnc2C#N)n1 +Cc1ccc(NC(=O)COC(=O)CCn2ccc3ccccc32)cc1 +CCc1onc(C)c1NC(=O)CCCC(=O)c1ccc(Cl)cc1 +CCCCCOc1cccc2c1C(c1cncn1C)NCC2 +CC(C)(C)CCNC(=O)CSc1nc(-c2cccnc2)n[nH]1 +Cc1ccn(S(=O)(=O)c2ccc(Cl)c(C)c2Cl)n1 +CCCS(=O)(=O)Nc1ccc2c(c1)CN(C(=O)C1CC1)CC2 +COc1cccc(C2CCCN2C(=O)c2sc(C)nc2C)c1 +O=C(CCC(O)c1ccc(F)c(F)c1)NC1CCCCC1 +N#Cc1cccc(OCc2cccc(C(=O)NCc3cccnc3)c2)c1 +CC(C)CNC(=O)NCCc1ccc(S(N)(=O)=O)s1 +CCc1ccccc1NC(=O)Cn1cnc2cc(Cl)ccc2c1=O +O=C(Nc1ccc2c(c1)OCCCO2)c1cccc(-n2cccc2)c1 +CCC(=O)N(CCc1ccccc1)c1ccccc1 +NC(=O)CCN(C(=O)Cc1cc2ccccc2[nH]c1=O)c1ccccc1 +CC(C)C(NC(=O)c1cccc(COc2cccc(F)c2)c1)C(N)=O +Cc1nnc2c(N3CCCC3)nc3ccccc3n12 +Cc1ccc(N2CC(C(=O)Nc3cn[nH]c3)CCC2=O)cc1C +CCc1ccccc1NC(=O)c1cc2c(nc1N)CCC2 +Cc1nn(C)c2ncc(C(=O)N3CCCCC3)cc12 +Cc1ccc(-c2csc3[nH]c(=O)[nH]c(=O)c23)cc1C +O=C(Cn1cnc2ccccc2c1=O)Nc1cccnc1-n1cccn1 +O=C(C1COCCO1)N1CCN(c2ccc(Cl)cn2)CC1 +CC(=O)N1CCCN(C(=O)C(NC(=O)c2ccco2)C(C)C)CC1 +COCC(NC(=O)Cc1cc(Br)ccc1F)C(N)=O +CNc1snc(C)c1C(=O)N1CCn2c(C)nnc2C1 +O=C(COc1ccccc1)NCc1cccc(Cl)c1 +CCCOC1CCCN(c2nccc(-c3cccnc3)n2)C1 +O=C(NCCC(O)c1ccc2c(c1)OCO2)c1ccc(F)cc1F +O=C(CC1COC2CN(c3ncccn3)CC12)NCc1ccco1 +CCN1CCc2nc(NC(=O)c3ccc(C)cc3O)sc2C1 +CCC1CCCCC1NC(=O)CCc1cccnc1 +COc1ccccc1OCC(O)Cn1cnc2cc(C)c(C)cc21 +Cc1ccccc1CC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +COc1cc(=O)n(CC(=O)NCC(C)C)nc1-c1ccccc1 +CCc1ccc(NC(=O)C(CC)n2c(N)nnc2SC)cc1 +CN(C)c1cc(C(=O)Nc2cccnc2-n2cncn2)ccn1 +CN1C(=O)Cc2cc(C(=O)N3CCN(c4ccccc4)CC3)ccc21 +CCc1ccccc1OCCN1CCC2(CCCO2)CCC1=O +CC(C(=O)Nc1ccc(Cl)cc1)c1nc(CO)cs1 +COc1ccc(-c2nc(Cn3ccnc3-c3cnccn3)no2)cc1 +COc1cccc(NC(=O)C2CC(=O)N(Cc3ccccn3)C2)c1 +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NC1CCCCC1C +COc1cc(OC2CCCCC2=O)c2c(C)cc(=O)oc2c1 +N#Cc1ccc(S(=O)(=O)N(CC2CC2)c2cccnc2)c(Cl)c1 +COc1cc(C)c(C)cc1-c1cc(C(C)=O)c(C)n1C +CC(C1CC1)n1nccc1NC(=O)CSc1nnc(C(C)(C)C)o1 +CCC1CN(C(=O)NCc2ccc(OC)nc2)CCO1 +CCCc1sc(C(=O)NC2CCN(C(=O)OC)CC2)cc1CC +CCOC(=O)CN(CC)c1ccccc1C(F)(F)F +CS(=O)(=O)c1ccc(C(N)Cn2cccn2)cc1 +CC(C)(CNC(=O)c1ccc(N2CCNC2=O)cc1)c1cccs1 +CCOC(=O)C(C)NC(=O)c1ccc(Br)cc1 +CCOC(=O)C1CCN(c2nnnn2-c2ccccc2)CC1 +CC(C)Cn1cc(N2CC(C(=O)N3CCN(C)CC3)CC2=O)cn1 +CN(Cc1ccncc1)Cc1c[nH]nc1-c1cccnc1 +Cc1cc(NC(=O)c2ccccc2)c(Cl)cc1N +CC(C)COC(=O)c1ccc(NC(=O)c2ccco2)s1 +Cc1nc(C)n(CC2CN(CC(=O)NC(C)(C#N)C3CC3)CCO2)n1 +CC(=O)Nc1cccc(-c2nc(-c3ccc(C)cc3)no2)c1 +COC(=O)N1CCC(NC(=O)c2ccc3c(c2)CCO3)CC1 +C#CCN(CC=C)C(=O)c1ccc(Cl)cc1NC(=O)CC +CCNc1cc(S(=O)(=O)NC(C)C(=O)NC)ccn1 +O=C(Cc1ccccc1)Nc1cc(NC(=O)C2CCCO2)ccc1F +CCCN1C(=O)C(C)Oc2c(OC)cc(CO)cc21 +COc1ccccc1C(C)NC(=O)Cn1c(=O)oc2ccccc21 +Cc1cc(C(=O)N(C)CCCc2cnn(C)c2)[nH]n1 +O=C(c1ccccc1)N1CCN(c2cc(N3CCCC3)ncn2)CC1 +O=C(COc1ccccc1Cl)NC1(CO)CCCC1 +Cc1cc2ncc(C(C)NCCNC(=O)c3cccs3)c(C)n2n1 +CC(C)CC(=O)Nc1ccc(N)c(Br)c1 +CCn1cnnc1-c1ccccc1NC(=O)NCc1ccc(C)s1 +CCc1nc(C2CCCN(C(=O)c3cc(COC)oc3C)C2)no1 +Cc1c(C(C)NC(=O)Nc2cn[nH]c2)cnn1-c1ccc(F)cc1 +CC(C#N)(c1ccc(Br)cc1)N1CCCC1 +Cc1ccc(C(=O)N2CCN(C(C)C(N)=O)CC2)s1 +CS(=O)(=O)c1ccc(C(=O)N2CCc3ccc(Cl)cc3C2)cc1 +Cn1cc(NC(=O)c2ccccc2N2CCOCC2)cn1 +CCCNC(=O)c1cc(S(=O)(=O)N(CC)CC)ccc1C +CCc1oc2ccccc2c1CN(C)C(=O)Nc1cnccc1C +c1csc(C2CCCN2c2ccc3nnnn3n2)c1 +c1coc(-c2nnc(SCCn3cncn3)n2C2CCCCC2)c1 +COc1ccccc1CC1CCCN1S(C)(=O)=O +CCC(NC(=O)c1c(C)cc(C)[nH]c1=O)c1nc(C)c(C)s1 +COc1ccccc1OCC(=O)N(C)c1cccc2ncccc12 +COC(=O)C1CCCCN1C(=O)CC=Cc1ccc(F)cc1 +N#Cc1cccnc1-n1c(-c2ccncc2)nc2cccnc21 +CC(NC(=O)c1ccccc1)C(=O)Nc1cc(F)cc(F)c1 +Cc1cccc(OCC(C)NC(=O)NCCc2c(C)nn(C)c2C)c1 +CCC1CN(C(=O)C(C)(OC)c2ccccc2)CC1N1CCOCC1 +Cc1ccc(Cc2nc(C(=O)OCCN3CCCC3=O)cs2)cc1 +C=CCSc1nnc(-c2cccs2)n1CC1CCCO1 +O=C(Nn1cnc2ccccc21)c1ccc(F)cc1Br +Cc1cccc(C)c1NC(=O)c1cc2c(=O)n3ccccc3nc2s1 +O=C(COc1ccc(F)cc1)Nc1ccc(-n2cncn2)c(F)c1 +O=C(CCC1CCCC1)Nc1noc2ccccc12 +O=C(NCC12CC3CC(CC(Cl)(C3)C1)C2)c1ccoc1 +CC(C)CN1C(=O)CCC2CN(C(=O)c3cc[nH]n3)CCC21 +CC(NC(=O)CCNC(=O)C(C)(C)C)c1nc(C(C)(C)C)cs1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1ccc(CC#N)cc1 +COCCNC(=O)c1sc(-c2ccccc2F)nc1C +O=C(NCCSc1ccccc1)c1sccc1C1CC1 +COC(=O)c1ccc(CSc2nnc(-c3ccco3)n2C)cc1 +COc1nc(C)ccc1CNC(=O)N1CCN(c2nccs2)CC1 +CN(C)C(=O)Cn1cc(C(=O)Nc2cccc(F)c2)nn1 +CC(C(=O)N1CCCCCC1)n1ccc2ncccc2c1=O +Cc1cc(Cl)ccc1OCC(=O)NC1CCCNC1=O +CCOc1ccc(C2=CCN(C(=O)c3cnccn3)CC2)cc1 +COc1cc(C)c(Cl)cc1-c1cc(C(C)=O)c(=O)n(C)n1 +CC(C(=O)N(C)CCC1(O)CCCC1)n1cccc1 +Cc1oc(-c2ccccc2)nc1Cn1c(=O)oc2cccnc21 +CC(C)NC(=O)C1CC2OCCN(C(=O)c3ccccc3)C2C1 +COc1ccc(NC(=O)c2ccccc2CC#N)cc1OC +CCN(Cc1ccccc1)C(=O)Nc1ccc(N(C)C(=O)OC)cc1 +Cc1ccccc1C(=O)Nc1nc(-c2cccc(N)c2)cs1 +CN(C(=O)c1cc2c(s1)S(=O)(=O)CC2)c1ccccc1 +COc1ncccc1CNC(=O)NCc1cccc(NC(C)C)c1 +COc1ccc(Cl)cc1CNc1nnc(C)s1 +COc1ccccc1NC(=O)C1Nc2cc(C)ccc2S(=O)(=O)N1 +COc1cc(Cl)ccc1C(=O)N1CCCC(n2cncn2)C1 +COCCCNc1cc(C(=O)N2CCOCC2)nc(C)n1 +CC(C)OCCN1CCN(C(=O)c2cccc(-n3cccn3)n2)CC1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)N(C)C)c(C)c1 +N#Cc1ccc(NCc2ccc(-n3ccnc3)nc2)c(F)c1 +CC(C)c1nc(CNS(=O)(=O)c2c[nH]c3ncccc23)cs1 +CCOc1ccccc1C(=O)NC1CCN(c2ccc(F)cc2)C1=O +Cc1nn(CC(C)C)c(C)c1CC(=O)NC1CCc2nnc(C)n2C1 +COc1ccc(NC(=O)NCC(OC)c2ccsc2)c(OC)c1 +CCC1CN(C(=O)c2cnn(C(C)CC)c2C2CC2)CC(C)O1 +Cn1nc(-c2ccc3c(c2)OCCO3)c2ccccc2c1=O +CCc1nc(C(C)NC(=O)NCc2cnn(C)c2)cs1 +O=C(NCC(O)C(=O)OCc1ccccc1)c1ccc(Cl)cc1 +O=C(NCc1ccc2c(c1)OCO2)c1cccn1-c1cccnc1 +CCOCC1CC2OCCN(C(=O)c3ccnnc3)C2C1 +O=C(Nc1cnn(C2CCOC2)c1)c1cc(-c2ccccc2)on1 +O=S(=O)(NCCc1cccs1)c1cccc(Cl)c1 +COC(=O)CCNC(=O)Nc1ccccc1OC +COc1ccc2c(c1)CCCN2C(=O)CCc1c(C)noc1C +COc1cccc(CCNC(=O)c2ccnc3ccccc23)c1 +O=C(CCc1ncc(-c2ccccc2F)o1)NCC1CCCO1 +CCC1CN(CC(=O)c2ccc(F)cc2F)CCO1 +CN(C(=O)CCNC(=O)C1CC=CCC1)c1ccccc1 +O=C(CN1CCN(CC(F)(F)C(F)F)CC1)NCC1CCCO1 +Cc1cc(NC(=O)c2cccs2)ncc1NC(=O)c1cccs1 +CC(C)C(=O)Nc1nnc(Cc2ccc(C(C)C)cc2)o1 +CCOC(=O)C(Cc1nccn1-c1ccccn1)NC +CN(CC#CCNC(=O)c1cn(C)nn1)Cc1ccccc1 +Nc1cnccc1C(=O)Nc1ccc(OC(F)(F)F)cc1 +CNS(=O)(=O)c1cccc(C(=O)OCC(=O)C2=NC=CC2)c1 +CC(C)(CC(=O)N1CCCC(CN2CCOCC2)C1)c1ccccc1 +CC(C)N(C)S(=O)(=O)c1cn(C)c(=O)n(C)c1=O +CSc1ccc(C(=O)N(C)Cc2ccc(OC(F)F)cc2)cc1 +O=C(c1csc2nc(-c3ccccc3)cn12)N1CCC(CO)CC1 +CCCNC(=O)c1cc(-c2ccccc2F)nc2onc(C)c12 +C#CCNS(=O)(=O)c1ccc(C(=O)NC(C)c2ccco2)cc1 +CCC(C)n1nccc1NC(=O)Cc1n[nH]c2ccccc12 +OCCCNc1ccc(-c2nc(Cc3ccc(F)cc3)no2)cn1 +O=C(CCC(O)c1ccc(Cl)cc1)N1CCOCC1 +CC(=O)c1ccc(N(Cc2ccco2)C2CC2)cc1 +COc1ccc(-c2cc3cc(F)ccc3[nH]2)cc1N +CCS(=O)(=O)N1CCC2(CC1)NC(=O)CC2c1cccnc1 +O=C(Nc1c(F)cccc1NC1CC1)c1cc(-c2ccncc2)on1 +COc1ccc(-c2nonc2NC(=O)c2ccccc2)cc1OC +COc1ccc(C)cc1-n1ccc(C(=O)N2CCOCC2C)n1 +CCCCOc1ncccc1CNC(=O)c1ccncc1F +CCOc1cccc2c1C(c1ccc(OC)c(O)c1)NCC2 +O=C(c1ccc2c(c1)COCO2)N(CC1CC1)CC1CC1 +c1ccc(-c2nn3c(-c4ccncc4)nnc3s2)cc1 +CC(Oc1ccc2c(c1)CCC2)C(=O)N1CCCn2ncnc21 +Cc1c(-c2nc(-c3ccc4c(c3)OCO4)no2)cnn1-c1ccncc1 +CC(CC(N)=O)C(=O)Nc1ccc(Cl)c(Cl)c1 +CCc1ccsc1C(=O)C(C#N)c1nc2ccccc2n1C +CC(NC(=O)Cn1ccccc1=O)c1ccc(Br)cc1 +Cc1cccc(CC(=O)NC2CCCc3ccccc32)c1 +Cc1ccc(NC(=O)CCNC(=O)C(C)(C)C)cc1F +CN(C(=O)c1cccc(NC(=O)NC(C)(C)CO)c1)c1ccccc1 +COC(=O)CCN(c1ccccc1)S(=O)(=O)c1ccc(C)cc1 +COc1ccc(C(NC(=O)c2cnccn2)c2nccn2C)cc1 +CCNC(=O)CNC(=O)c1c[nH]nc1-c1ccc(OC)cc1 +CCc1c(C(=O)NCC2CCOC2)cnn1-c1ccccn1 +COc1cc(OC)c(C(=O)NC(C)c2c(C)noc2C)cc1OC +CCN(CCC#N)C(=O)c1ccc(C#CCO)cc1 +CCC(=O)c1ccc(OCC(=O)NC(C)c2ccncc2)cc1 +Cc1noc(C)c1S(=O)(=O)Nc1ccc2c(c1)OCCO2 +Cc1cc(O)cc(C)c1NCC=Cc1ccccc1 +Nc1ccc(S(=O)(=O)Nc2cc(F)ccc2Br)cc1 +O=C(c1ccc2[nH]cnc2c1)N1CCN(c2ccccc2F)CC1 +CC(C)c1n[nH]c(SCC(=O)NCc2ccc(Cl)cc2)n1 +COc1n[nH]c(-c2ccncc2)c1Br +Cc1nc(C)n(CCC(=O)NC2CCCOC2)n1 +CN(C)C(=O)CN1CCN(Cc2nnc(Cc3ccccc3)o2)CC1 +CC(C)(C)C(=O)Nc1ccccc1C(=O)NCc1ccccc1 +O=C(Nc1cc(C2CCOCC2)[nH]n1)c1ccc2[nH]cnc2c1 +COCCNC(=O)C(N)c1cc(OC)ccc1OC +CC(C)N(C(=O)Cn1cc(C(F)(F)F)ccc1=O)c1ccccc1 +Cc1cccc(-c2nc(CNC(=O)c3cccnc3)cs2)c1 +CC1CCN(C(=O)c2nc(S(C)(=O)=O)n3ccccc23)C(C)C1 +Cc1ccc(N2CCC(C(=O)NCCC(=O)OC(C)C)C2=O)cc1 +CC1CCCCC1NC(=O)Cn1nnc(-c2ccsc2)n1 +O=C(NCc1cccnc1)c1cccc(CN2CCOCC2)c1 +CCc1c(C(=O)N2CCCC(C)CC2)cnn1-c1ccc(OC)nn1 +O=C(CN1CCCS1(=O)=O)Nc1ccc2c(c1)oc1ccccc12 +O=C(CNS(=O)(=O)c1ccccc1F)NCc1ccco1 +CCn1c(C)cc(C(=O)Nc2cc(C)ccn2)c1C +CCN(CC)C(=O)c1ccc(OCC(=O)N2CCN(C)CC2)cc1 +CC(C)CCNC(=O)C1Cc2ccccc2C(=O)O1 +COc1ccc(C(C)=O)cc1CC(=O)Oc1ccc(C(C)=O)cc1 +Cc1ocnc1C(=O)Nc1ccc(Oc2cccnc2)nc1 +Cc1occc1COC(=O)CSc1ccccc1F +CCN(Cc1cccc(F)c1)C(=O)C1CC(=O)N(Cc2ccco2)C1 +CCN(CC(F)(F)F)C(=O)CCc1ccccc1N +O=C(OCc1cccnc1)C1(c2ccc(F)cc2)CCOCC1 +CCN(CCC#N)S(=O)(=O)c1ccc2c(c1)OCO2 +CC(=O)NCCOc1cccc(Oc2ccccc2)c1 +O=C1CCCCC1Sc1nc(C2CCCC2)n[nH]1 +CCc1n[nH]c(C2CN(C(=O)CCc3cscn3)CCO2)n1 +O=C(Cc1cccs1)N1CCC(n2c(=O)[nH]c3cncnc32)CC1 +CC(C)CNC(=O)CNC(=O)c1ccc2c(n1)NC(=O)CS2 +COc1cc(C2NCCc3c2ccc(C)c3O)ccn1 +Nc1cnn(CC(=O)N2CCC(Cc3ccccc3)CC2)c1 +CCc1cccc(C)c1NC(=O)COc1ccc(C(C)=O)cc1OC +Cn1c(CCNC(=O)c2cn3ccccc3n2)nc2ccccc21 +Cc1ccc(-c2nn3c(CO)c(-c4ccco4)nc3s2)cc1 +CCc1onc(C)c1C1CCCN1C(=O)c1ccc(C)cc1 +O=C(c1ccc2nc3ccccc3c(=O)n2c1)N1CCCCC1 +CNS(=O)(=O)c1ccc(NC(=O)c2cnn(C)c2)cc1 +CC(C)CN(C)C(=O)Nc1ccccc1N1CCCC1 +COC(CNC(=O)Cc1cccs1)c1ccccc1C +Nc1cc(NC(=O)CCOC2CCCC2)ccc1Cl +CC(NC(=O)Cc1ccsc1)c1ccccc1N +COc1cccc(NC(=O)CNC(=O)C2Cc3ccccc3CN2)c1 +CCn1c(=O)c2c(nc(SCc3ccc(C)cc3)n2C)n(C)c1=O +CCn1c(SCC(=O)Nc2ccccn2)nnc1-c1ccccc1 +O=C(Nc1ccc(F)cc1F)c1cnc2n(c1=O)CCS2 +O=C(Cc1cn2ccsc2n1)Nc1cc(F)cc(F)c1 +Cc1ccc(NC(=O)NCc2ccc(-n3ccnc3)c(F)c2)c(C)c1 +COc1ccnc(NC2CCCc3c2cnn3Cc2ccccc2)n1 +Cc1cc(CN(C)C(=O)NC2CCN(c3ncccn3)CC2)no1 +NC(=O)CSc1nc(CN2CCOCC2)nc2ccccc12 +Cn1cc(NC(=O)N2CCC2c2ccccc2)nn1 +Cc1nn(CCC#N)c(C)c1CCC(=O)Nc1ccccn1 +Cc1c(NC(=O)c2cc[nH]n2)cccc1C(=O)N1CCCC1 +CCn1nnnc1NCc1c(Cl)cccc1Cl +CC1(NS(=O)(=O)N2CCCCC2)Cc2ccccc2C1 +CCCN1C(=O)C(CC)(CC)Oc2c(OC)cc(CO)cc21 +CN(CC1COc2ccccc2O1)C(=O)c1ccoc1 +CCc1c(C(=O)NC(CC)C(C)C)[nH]c(C)c1C(C)=O +Cn1nc(C(=O)NCc2cccnc2)cc1NC(=O)c1cccs1 +COc1ccccc1OCCNC(=O)c1ccc(C)o1 +O=C(CCCc1cc(F)ccc1F)Nc1ccn(CC(F)F)n1 +CC(=O)OC(C#CCN1CCOCC1)(C(C)C)C(C)C +Cc1oc(C(=O)NC(c2ccccc2)C2CCC2)cc1S(N)(=O)=O +CCOc1cc(C)c(CCCn2cc(N)cn2)cc1C +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1 +CCCC1CC(C(=O)NCCc2nc3ccccc3n2C)CCO1 +CCOC(=O)c1nc(-c2ccccc2)oc1N1CCOCC1 +Cc1ccc(F)c(C(=O)N2CCC(CC(=O)N3CCCC3)CC2)c1 +CCN(Cc1ccc2c(c1)OCCO2)S(=O)(=O)N1CCOCC1 +COCCc1ccc(OCC(=O)NC2CCOc3ccccc32)cc1 +FC(F)(F)Oc1cccc(NCc2cncs2)c1 +COc1ccc(C(=O)N2CCc3cc4cc(C)ccc4nc32)cc1OC +O=C(NC1CC2CCC1C2)c1cc(COc2ccccc2F)[nH]n1 +N#Cc1nn(Cc2cccc(Cl)c2)c2c1C(=O)CCC2 +Cc1cc(C(=O)N2CCCC(Nc3ccc(F)cc3)C2)c(C)o1 +Cc1nc(C(C)N(C)C(=O)Nc2ccc3c(c2)OCO3)c(C)s1 +COc1ccccc1-c1noc(COc2ccccc2C#N)n1 +Cc1ccc(C(C)C)c(OCCNS(C)(=O)=O)c1 +COC(=O)Cc1csc(NC(=O)c2cc(C)c(C)s2)n1 +CCOc1ccccc1NC(=O)Nc1ccc2c(c1)CC(=O)N2CC +CC1CCC(NC(=O)CN2CCN(C(=O)C3CCCC3)CC2)CC1 +N#CC1(C(=O)N2CCC(OCc3ccccc3F)CC2)CCCCC1 +Cc1ccc2c(c1)NCCN2CC(=O)c1cccs1 +NC(=O)C1CCCC(NC(=O)Nc2ccc3c(c2)COC3)C1 +COc1ccccc1CCNC(=O)c1nnn(-c2ccc(F)cc2)n1 +CCOc1c(Cl)cccc1NC(=O)NCCCC(N)=O +CCOC(=O)NC1CCCN(C(C)C(=O)Nc2nccs2)C1 +COCC(C)NC(=O)c1cccc(-n2cnnn2)c1 +CN(C)C(=O)C12CCC(C)(c3nc(C#N)c(C#N)nc31)C2(C)C +Cc1ccc(-c2ccnc(NC(C)c3n[nH]c(C)n3)n2)c(C)n1 +Cc1cccc2c1OCCCC2Nc1cnn(C)c1C +Cc1csc(NC(=O)c2coc(NC(=O)c3cccs3)n2)n1 +CCN(C(=O)c1csc(-c2ccco2)n1)C1CC1 +CC(OCC(F)(F)F)C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +O=C(NCc1ccco1)c1cccn1Cc1nc(-c2ccccc2)no1 +O=C(c1cc(Cl)ccn1)N1CCC(O)(C(F)(F)F)CC1 +CCOC(C(=O)c1ccccc1)n1nnc2ccccc21 +CN(C)c1nc2sc(C(=O)Nc3nc[nH]n3)cc2s1 +CCC(=O)Nc1ccc(C(C)NC(=O)N(CC)Cc2ccoc2)cc1 +OCCOCCNc1nc2sc3c(c2c2ncnn12)CCC3 +Cc1cccc(C(N)=O)c1NCc1cccc(C#N)c1 +COc1cc2c(c(CN3CCCC(c4nncn4C)C3)c1)OC(C)C2 +CC(C(=O)NC1CC1)N1CCN(Cc2ccn(C)c(=O)c2)CC1 +Cc1nccn1-c1ccc(NC(=O)C2CC=CC2)cn1 +Cc1ccc(CNC(=O)NCC2COc3ccccc3O2)n1C +CC(=O)c1cc(C(F)(F)F)nn1Cc1ccccc1 +CCC(C)n1ncc(C(=O)NC(C)c2cc(C)oc2C)c1C1CC1 +CCCCCCNC(=O)Cc1noc2c(C)cc(N)cc12 +Cc1ccccc1CN(C)C(=O)Nc1ccc(N2CCOC2=O)cc1 +CCCCNC(=O)c1sc2ncnc(NCc3ccco3)c2c1C +Cc1nc(-c2ccc3c(c2)CCN3C(=O)C2CCCC2)cs1 +COC(=O)c1ccc(NCc2ccc(C#N)cc2)c(C)c1 +N#Cc1ccccc1CSc1nnc(COc2ccccc2)o1 +CC(C)(C)OC(=O)N1CCC(Oc2ncccc2O)C1 +CCCCN(CC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2n1C +COc1cccc(NC(=O)NCCc2nc3c(F)cccc3n2C)c1 +O=C(COc1ccc(C(=O)N2CCCC2)cc1)NC1CCCCC1 +COc1ccc(S(=O)(=O)N2CCCC(O)C2)cc1 +Cc1cccc(-c2csc(C(N)=O)c2-n2cccc2)c1 +Cc1[nH]c(C(=O)N2CCc3sccc3C2)c(C)c1C(=O)OC(C)C +Cc1cc(N)n(CC(=O)NC(C)Cc2ccsc2)n1 +CCOC(=O)c1cnc(C(F)(F)F)nc1-c1ccccc1OC +Cn1cc(C(N)=O)cc1C(=O)OCc1ncc(C(C)(C)C)o1 +O=C(CCC(=O)c1ccccc1)NC1CCSc2ccc(F)cc21 +CC(C)(C)NC(=O)c1ccccc1NC(=O)COc1ccccc1 +Cc1c(NC(=O)Nc2ccc(F)cc2)c(=O)n(-c2ccccc2)n1C +CC(C)CCN(C)C(=O)C1CC(=O)N(Cc2ccccn2)C1 +Cc1ccc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1 +O=C(c1ccc(C(F)(F)F)cc1)N1CC(c2nc3ccccc3[nH]2)C1 +Cc1cc(OCCc2c[nH]c3ccccc23)ncc1N +O=c1c(Sc2ncc(-c3ccc(F)cc3)o2)nccn1C1CC1 +CCN(CCCNC(=O)Nc1ccncc1)S(C)(=O)=O +COC(=O)c1cnn(-c2nc3c(C)cccc3s2)c1C +CCOC(=O)c1cnc(C(=O)NCc2ccnn2C)c(Cl)c1 +Cc1c(C(=O)OCC(N)=O)cnn1-c1ccccc1F +O=C(NCCSc1ccccn1)C1CC(=O)N(C2CC2)C1 +CNC(=O)C(C)NC(=O)c1nc(C(C)C)ncc1Cl +Cn1cnc(CNC(=O)N2CCN(c3ccc(C#N)cc3F)CC2)n1 +CC(C)Nc1nnc(-c2cnc(-c3ccncc3)s2)s1 +Cc1n[nH]c(C)c1CCn1cc(-c2cncnc2)nn1 +Cc1ccc(NC(=O)c2cc(N)cnc2C)c(F)c1 +O=C(NCc1cccnc1-n1cccn1)c1cc(-c2cccnc2)on1 +CCC1CCCCN1S(=O)(=O)c1cnn(C)c1 +Cc1cnn(CC2CN(Cc3ccc(F)c4cccnc34)CCO2)c1 +CCc1ccc(-c2n[nH]c(SCC(=O)N(CC)CC)n2)cc1 +Cc1nc(Nc2nc(C)c3ccccc3n2)nc2c1C(=O)CCC2 +Cc1nc2ccc(F)cc2c(=O)n1CCNC(=O)CC(C)C +COc1cc(Nc2ccccc2N)cc(OC)c1OC +CCC(C)NC(=O)c1ccc2c(c1)N(C)C(=O)CS2 +CCS(=O)(=O)N1CCN(C(=O)c2ccc(F)c(F)c2)CC1 +c1cnc2c(OCCn3cnc4ccccc43)cccc2c1 +CC(=O)Nc1ccc(NC(=O)c2cc(C)cc(C)c2)cc1 +CC(Cc1cn(Cc2ccccn2)nn1)c1ccccc1 +CCCOc1ccccc1NC(=O)c1ccc[nH]c1=O +COc1ccc(C2=NC(=C3C=CC=CN3C)C(=O)O2)cc1 +CC(=O)N(C)c1ccc(NC(=O)CNc2ccc(Cl)cc2)cc1 +Cc1cc(C)nc(NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)n1 +COc1ccc(C(=O)N(C)C(C)c2ccc(Cl)cc2Cl)nn1 +COc1ccc(OCC(C)NC(=O)c2ccccc2F)cc1 +Cc1noc(C)c1CNC(=O)NCc1ccccc1-n1cccn1 +Cc1cccc(-n2nnnc2SCC(=O)NCC(F)(F)F)c1C +CCCn1cc(NCc2ccc(C)s2)ccc1=O +O=C(NC1CCCC1)N1CCC(Oc2ccccc2)CC1 +Cn1nccc1CNC(=O)c1cccc(OCc2cccs2)c1 +Cc1cc(C(=O)N2CCCC2Cn2cccn2)c(C)n1CC1CC1 +CC(C)N(C(=O)C1CCN(C(=O)OC(C)(C)C)C1)C1CCOCC1 +Nc1nncn1C(=O)COc1ccc(Br)cc1Cl +Cc1ccc(Oc2ncnc(N3CCCC(C)C3)c2N)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)NC1CCN(C(C)=O)C1 +O=C(OCCn1nc2ccccn2c1=O)C12CC3CC(CC(C3)C1)C2 +Nc1c(NCc2ccco2)ncnc1Sc1ccccc1 +CS(=O)c1ccc(CN2CCOCC2C2CC2)cc1 +Cc1ccc(OC(C)C(=O)N(C)C2(C#N)CCC2)cc1 +CCCNC(=O)Nc1ccccc1C(=O)N(CC)CC +CCSc1cc(C(=O)Nc2ccc(SC)cc2)ccn1 +COc1ccccc1C(=O)OCC(=O)N1CCCCCC1 +COc1ccc(CNC(=O)CCc2ccsc2)cc1 +COC(=O)c1cc(-c2ccc(OC)cc2OC)[nH]c(=O)n1 +COc1ccc(Cl)cc1C(=O)Nn1cnc2ccccc2c1=O +CCc1nnc(NC(=O)C(Cc2ccccc2)n2cnnn2)s1 +COc1ccc(CC(=O)Nc2cccc3ncccc23)cc1F +CCSc1nc(=O)n(CCCO)c2c1CCCC2 +COc1ccc(C)cc1NC(=O)CC1COc2ccccc2NC1=O +CCN(C(=O)NCCN1CCOCC1)C1CCCC1 +O=C1CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +CC(=O)c1c[nH]c(C(=O)Nc2ccc(CCN3CCOCC3)cc2)c1 +N#Cc1c(F)cccc1NC(=O)Cc1ccccc1Cl +CNC(=O)C(C)Oc1ccc2ccccc2c1Br +CNC(=O)C(CC(C)C)NS(=O)(=O)c1cccnc1 +O=C(NCc1ccc(F)cc1)C1CCCN(C(=O)NC2CC2)C1 +CNC(=O)NCC(=O)Nc1cnc(-c2ccccc2)nc1 +CC1=C(C(=O)Nc2ccc(C)cc2)C(c2ccncc2)n2ncnc2N1 +COc1cc(F)c2c(c1)C(CC(C)(C)C)NCC2 +Cc1cc(C2CCCN(C(=O)CC(C)n3cccc3)C2)n[nH]1 +Cc1cccc2[nH]cc(CCNC(=O)N(C)Cc3ccncc3)c12 +Cc1cc(N(C)C)nc(CNC(=O)Nc2ccc(C)c(F)c2)n1 +O=C1CCN(C(=O)c2ccc(-c3ccccc3)cc2)CCN1 +CCOCCCn1c(C2CC2)nc2cc(Cl)ccc21 +Cc1noc(C)c1CN(C)C(=O)c1cscn1 +Cc1ccc2ncc(C(=O)N3CCN(c4nc(C)ns4)CC3)n2c1 +NC(=O)c1cccnc1N1CCN(C(=O)CC2CCCC2)CC1 +CC(c1cccs1)N(C)C(=O)CCN1CCCCCC1=O +CC(NC(=O)COc1ccc(Br)cc1)C1CCCO1 +CN1Cc2ccccc2CC1C(=O)N1CCCCC1 +Cc1ccccc1OCC(=O)Oc1ccc(-n2cnnn2)cc1 +C#CCOc1ccc(C(=O)NCc2cn(-c3ccccc3)nn2)cc1 +CCNC(=O)NC1CCC(OC(=O)C2CC3CCC2C3)CC1 +Cc1ccc(CN(C)C(=O)C(C)Oc2ccc(Cl)cc2)o1 +O=S(=O)(NCc1ccccc1)Nc1ccccc1CCO +CC(=O)Nc1ccc(NC(=O)CCCNC(=O)c2ccccc2)cc1 +Cc1nn(C)c(C)c1CCC(=O)Oc1cccc(Br)c1 +Cc1ccc2c(c1)C(=O)CC2CC(=O)N1CCOCC1 +Cc1ccc(C)c(C(=O)N2CCC(N3CCNC3=O)CC2)c1 +CCc1nc(CNc2cccc(NC(=O)OC)c2)no1 +Cc1noc(NC(=O)c2ccc(OCC(F)F)nc2)n1 +CNC(=O)c1nnsc1S(=O)c1ccc(Cl)cc1 +CC(C)C(O)c1c(Br)ccc(F)c1F +CCOc1ccc(C(=O)Nc2cccc3nc(C)ccc23)nn1 +COc1ccccc1C1(C(=O)NCC(O)Cc2ccccc2)CC1 +Cc1cccc(NCC(=O)NCc2cccc(Cl)c2)c1C(N)=O +Cc1ccc(OCCN(C)C(=O)c2ccnc(-n3ccnc3)c2)cc1 +CC1CCN(c2ccccc2NC(=O)c2cccnc2)CC1 +CCOC(=O)C1(NC(=O)C2CCOCC2)CCCCC1 +CCn1c(SCC(=O)N2CCCC2)nnc1C1CC1 +O=C(c1cc(F)cc(F)c1)N1CCc2ccccc21 +Cc1cc(C(=O)N2CCNC(=O)C2)c2ccccc2n1 +O=C(Nc1ccccc1C1OCCO1)OCc1ccccc1 +Cc1cc(N)ccc1SCC(=O)NCc1cccs1 +CSc1ccc(NC(=O)NCc2cc(Cl)ccn2)cc1 +COc1ccc(CNc2ncnc(SC)c2C#N)cc1OC +CC(=O)N1CCC2(CC1)CC(c1ccccc1)C(=O)N(C1CC1)C2 +CC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)n1 +CCCCc1ccc(CC(=O)N(C)CC(=O)N(C)C)cc1 +COc1cc(N)ccc1NC(=O)COc1cc(C)ccc1C +O=C(Nc1ccccc1F)N(Cc1ccccn1)C1CC1 +CC1CN(C(=O)CCNS(C)(=O)=O)CC(C)O1 +Cc1nc(CC(=O)N(C)Cc2csc(-c3cccs3)n2)cs1 +Cc1ccccc1-c1nnn(CCn2c(=O)oc3ccccc32)n1 +CC(=O)Nc1cccc(C(=O)Nc2cc(Cl)cc(Cl)c2)c1 +CCCn1cnnc1C1CCN(C(=O)c2ccc(OC)nc2)CC1 +COc1ccc2cc(C(=O)NCc3ccc4c(c3)OCCO4)ccc2c1 +C#CCNC(=O)CSc1nc(C2CC2)nc(C)c1C#N +COCCNC(=O)c1cc(-c2c[nH]c3ccccc23)nc2ccccc12 +COc1ccc(NC(=O)CC2Oc3ccccc3NC2=O)c(OC)c1 +O=C(CNC(=O)NC1CCCC1)Nc1ccc(F)cc1 +COc1ccccc1CCNC(=O)c1cc(-c2cccnc2)on1 +Cc1nc(C)c(CNC(=O)N2CCCCC2c2cn[nH]c2)s1 +Nc1c(-c2ccccn2)noc1C(=O)N1CCOCC1 +Brc1cc(-c2ccco2)cc2[nH]ncc12 +CS(=O)(=O)c1ccc(N2CCC(C(N)=O)CC2)c(Cl)c1 +CCOc1ccc(CN(C)c2cccc(N)c2)cc1 +O=S(=O)(Cc1ccccc1Cl)N1CCN(C2CC2)CC1 +C=CCN(CC=C)C(=O)COn1nnc2ccccc21 +COc1cc(S(=O)(=O)n2cccn2)c(OC)cc1Cl +COc1ccc(CCC(=O)N2CCOC(C)(C)C2)cc1F +Cc1noc(C)c1C1CCCN1C(=O)c1cccc(-n2cnnc2)c1 +O=C(NCC(=O)N1CCCC1)NCc1ccccc1 +CCn1nc(C)c(CCNC(=O)c2ccc3c(c2)OCCO3)c1C +O=C(NCCCc1ccccc1)C1COc2ccccc2O1 +CC(C)CC(CNS(=O)(=O)c1cnn(C)c1)N1CCOCC1 +CCOC(=O)Nc1cccc(NC(=O)c2ccccc2F)c1 +O=C(CCCC(O)c1cccs1)N1CCOCC1 +CN(C)c1ccc(NC(=O)c2ccc(F)c(F)c2)cn1 +CCOC(=O)CCCC(=O)c1ccc(F)cc1F +COc1ccccc1CN(C)C(=O)c1cc(CN2CCOCC2)on1 +Cc1n[nH]c(C)c1C(C)CC(=O)NCC1(c2ccncc2)CC1 +O=c1c2ccccc2n2cnnc2n1-c1ccccc1 +COc1ccc2nc(SCC(=O)NC(C)(C#N)C(C)C)[nH]c2c1 +O=C(Nc1ccccc1N1CCOC1=O)N1CC2CC=CCC2C1 +Cc1cc(Cl)cc(C)c1CN1CCN(c2cnn(C)c2)C(=O)C1 +CS(=O)(=O)c1cccc(C(=O)OC2CCCc3ccccc32)c1 +Cc1ccc(-c2cc(C(=O)NCC(C)N3CCOCC3)no2)cc1 +CC(C)OC(=O)c1ccc(NC(=O)CSc2nccn2C)cc1 +COC(=O)c1ccccc1N(C)C(=O)CSc1nncs1 +CCCCCNC(=O)C(N)c1ccc2[nH]ccc2c1 +CN(C)c1cccc(C(=O)Nc2ccccc2N2CCNC(=O)C2)c1 +c1cnc(N2CCC3(CC2)COCCN(Cc2cccnc2)C3)nc1 +CC(C)N1CCOC(CCNC(=O)c2n[nH]c3ccccc23)C1 +O=C(Oc1ccc2ccc(=O)oc2c1)c1cccnc1OCC(F)F +CCOc1c(N)cc(C)cc1C(=O)c1cccc(N)c1 +CCc1ccc(C(=O)N2CCC3(CCCN(CCO)C3=O)C2)[nH]1 +CCC(CC)CN(CC)S(=O)(=O)c1cnn(C)c1 +CC(C)Cn1ncc(C(=O)N(C)C2CCC2)c1C1CC1 +O=C(OCC(=O)N1CCc2ccccc21)c1ccccn1 +Cc1cccc(C)c1NC(=O)c1cc(OCc2ccccc2)no1 +CC1Cc2ccccc2N1C(=O)C1CC(=O)N(C2CCCCC2)C1 +COc1ccc(C(=O)Nc2cccc(O)c2)cc1OC +O=C(COc1ccc(CO)cc1Br)NCC1CC1 +O=C(NCc1cccs1)Nc1ccc2[nH]c(C(F)F)nc2c1 +COC(=O)c1sccc1S(=O)(=O)NC(=O)c1cccs1 +N#Cc1ccc(S(=O)(=O)NCc2ccc3c(c2)OCCO3)cc1 +CCOc1ccccc1NCC(=O)N1CCCCC1C +CC1CC1c1ccc(CN(C)C(=O)CN(C)S(C)(=O)=O)o1 +CC(O)CNC(=O)c1ccc(-c2cccc(F)c2)o1 +CCN(Cc1cc(-c2cccc(OC)c2)on1)C(=O)C(C)C +CS(=O)(=O)c1coc(C(=O)c2cscn2)c1 +Cc1cc2n(c1)-c1ccc(Br)cc1NC2 +O=C(NCC1(O)CCOCC1)Nc1ccccc1C(F)(F)F +Nc1ccccc1CCc1nnc(N2CCCC2)s1 +CC(C)(C)NC(=O)CNC(=O)NCCc1ccccc1F +O=C(Nc1ccc(F)cc1Cl)c1cccc(N2CCCC2=O)c1 +CCCn1c(=O)n(CCO)c(=O)c2cc(OC)c(OC)cc21 +CNC(=O)NCC(=O)NCC(c1ccc(C)cc1)N1CCOCC1 +Nc1nc2cccc(-c3ccc4c(c3)OCO4)n2n1 +COCCn1cnc2c(sc3nc(C)c(C)cc32)c1=O +COCCN1C(=O)CCC2C1CCN2C(=O)Cc1ccccc1 +CCOCC1CCN(C(=O)Nc2cc(F)c(OC)cc2OC)C1 +Cn1nccc1CNC(=O)NCc1cccc(CN2CCCC2=O)c1 +O=C(c1cccc(C(F)(F)F)c1)N1CCc2ncncc2C1 +CCN(C)C(=O)Cn1c(=O)n(CC)c2ccccc21 +CC(=O)c1ccc(OCC(=O)NCCN2CCc3ccccc32)cc1 +CC(=O)N1c2ccccc2CC1C(=O)Nc1cc(CC(C)(C)C)n[nH]1 +CC(=O)N1CCCC1C(=O)Nc1ccc(Sc2nccn2C)cc1 +CCn1cnc2cc(-c3noc(CNC(=O)c4ccco4)n3)ccc21 +CNS(=O)(=O)c1ccc(NC(=O)c2ccc[nH]c2=O)cc1OC +COc1ccc(C2(Cc3cccs3)NC(N)=NC2=O)cc1OC +CCN(CC(C)C#N)C(=O)c1n[nH]c2ccc(C)cc12 +COc1ccc2nc(NC(=O)NC(CO)c3ccccc3)sc2c1 +O=C1COc2ccc(C(=O)N3CCCCC3)cc2N1 +CCN(Cc1nc(C(C)C)no1)C(=O)C1COc2ccccc2C1 +CC(=O)Nc1ccc(NS(=O)(=O)c2cc(C)ccc2C)cc1 +COc1ccc(C(O)CN2CCN(C(=O)OC(C)(C)C)CC2)cc1 +COC(=O)c1ccc2c(c1)nc(CCO)n2C(C)(C)CO +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCCOC1CCCCC1C +CCN(CC)C(=O)c1csc(-c2cccc(OC)c2OC)n1 +CCc1nnc(SCC(=O)Nc2ccc(OC)cc2)n1C +CCc1ccccc1N1CC(C(=O)N2CCN(CCO)CC2)CC1=O +N#Cc1c(-c2ccncc2)c2c([nH]c1=O)-c1ccccc1CC2 +NC(=O)c1nn(-c2ccccc2F)sc1=NC(=O)c1ccccc1 +CC(C)c1c(C(=O)N2CCCCC2)cnn1-c1ccccc1 +COc1ccc(CC(=O)NCC(O)c2ccsc2)cc1OC +CCOc1ccc2c(c1)C(NC(C)=O)C(=O)N2CCN1CCOCC1 +CC(NC(=O)c1ccc(=O)[nH]c1)c1ccc(S(C)(=O)=O)cc1 +c1ccc(COCc2cn(CC3CCCO3)nn2)cc1 +O=C(NCCN1CCOCC1)C1(c2cc(-c3ccco3)on2)CC1 +CCn1c(-c2ccc(OC)cc2OC)ccc(N)c1=O +COc1ccccc1CNS(=O)(=O)c1c(C)noc1C +NC(=O)c1c(F)cccc1-c1cccc2c1OCC2 +CC(C#N)NS(=O)(=O)c1cc(Cl)cc2c1OCC2 +COC(=O)c1ccc(C(F)(F)F)cc1NCc1nccn1C(F)F +Cc1noc(C2CCCN(C(=O)NCc3cccc(C#N)c3)C2)n1 +Cc1cc(C)c(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)c(C)c1 +CCC1N(C(=O)c2ccncc2)CCCC12CCC(=O)N2 +CN(C)c1cnn(CC(=O)N2CCN(CC3CCCO3)CC2)c(=O)c1 +Cc1nccnc1N1CCC(O)(C2CCOCC2)C(C)C1 +COc1ccc(CN2CCn3c(nnc3C3CC3)C2)cc1F +COc1ccc(OC)c(NC(=O)c2ccc3c(c2)CCC3)c1 +N#Cc1ccccc1Cn1cc(C(F)(F)F)ccc1=O +CC(C)(C)n1ncc(NCc2ccco2)c(Cl)c1=O +O=C(c1cccnc1)N1CCOC2(CCCN(c3nncs3)C2)C1 +O=C(c1ccc(-n2ccnc2)nc1)N1CCCC(n2cccn2)C1 +Cc1ccc(-n2nc(C)cc2NC(=O)Cc2cccc(F)c2F)nn1 +CCN(c1ccccc1)c1nc2nonc2n2c(C)nnc12 +CC(=O)c1c(C)nn(CC(=O)N2Cc3ccccc3C(O)C2)c1C +CC1CCCC(N(C)C(=O)CC(NC(N)=O)c2cccs2)C1 +COc1ccc(Cl)cc1C(O)CNc1ccccc1F +O=C(NC1CCN(C(=O)Nc2ccccc2)CC1)c1ccc[nH]1 +CC(C)CC(=O)N1CC2CCN(c3ncccn3)CC2C1 +COCc1nc(COc2cccc(OC)c2)sc1CC#N +Cc1cc(=O)[nH]c(C2CCN(S(=O)(=O)N3CCOCC3)CC2)n1 +CC1(C)OCC2(CO1)CN(C(=O)c1cccc(-n3cnnn3)c1)C2 +CCN(CC)C(=O)c1cc2c(s1)S(=O)(=O)CC2 +COC(=O)c1ccnc(NCc2c(OC)cccc2OC)c1 +CCOC(=O)Cn1nc(C)c2c1N=C(O)CC2c1cccc(O)c1 +Cc1cc(=O)oc(C)c1C(=O)OCCCCC(=O)N(C)C +Cc1nc2nc(C(C)C)nn2c(C)c1CC(=O)Nc1ccc(F)cc1 +Nc1ccc(C(=O)NCc2ccc(Cl)cc2)nn1 +CC(C)(C)OC(=O)NCCNC(=O)NC1CCC(O)CC1 +COc1cc(C2c3c(-c4ccc(C)cc4)n[nH]c3C(=O)N2C)ccc1O +CC(C)NC(=O)Cn1nc2n(c(=O)c1=O)CCN2c1ccccc1 +Cc1occc1-c1nnc(SCc2ccccc2C#N)o1 +COc1ccc(OC)c(NC(=O)CC2Oc3ccccc3NC2=O)c1 +COc1ccc(-c2ccc(CC#N)c(=O)[nH]2)cc1OC +O=C(NCCC(=O)N1CCCC1)C1CN(Cc2ccccc2)CCO1 +Cc1ccccc1NC(=O)C1CCN(C(=O)C2CC2)CC1 +Brc1ccccc1-c1nc(-c2ccc3nncn3c2)no1 +Cc1nc(C)n(CC2CCCCN2c2ccc3nnnn3n2)n1 +COC1(OC)C(C#N)C(c2ccc(N)cc2)C1(OC)OC +Cn1cnc2cc(OC(=O)NCc3ccccc3)ccc21 +O=C1CCCN1CC(=O)N1CCCC(COc2ccc(F)cc2)C1 +CCOC(=O)C1CCCN(C(=O)C2CN(C(C)=O)C2)C1 +C=CCN(C(C)=O)c1nc(-c2c[nH]c3ccccc23)cs1 +CCOC(C)C(=O)Oc1cc2oc(=O)cc(C)c2cc1CC +COCCCNC(=O)C1CCN(c2nc(C)cc(OC)n2)CC1 +C#CCN1CCN(C(C)C(=O)NCc2ccc(OC)c(OC)c2)CC1 +N#Cc1ccccc1NS(=O)(=O)c1ccc(F)cc1 +CC(C)n1cc(O)c(=O)cc1CN(CCO)Cc1ccccc1 +CCCn1nnnc1Cn1cnc2sc(C)cc2c1=O +CC(C)c1noc(-c2ccc(NCC3CCCCO3)nc2)n1 +Cc1nonc1NC(=O)C(C)Oc1ccccc1Br +COc1ccc(C2CCCN2c2ccc(C#N)cn2)c(OC)c1 +CCC1CC(=O)OC1(C)C(=O)CSc1nc2ccccc2s1 +CC1CN(c2ncnc3cc(F)c(F)cc23)CC(c2ccccc2)O1 +COCC(=O)N(C)CC(=O)Nc1c(C)cc(Br)cc1C +Cc1ccc(C(=O)Nc2cccc(C(=O)NCC(F)(F)F)c2)cn1 +CCc1cc(NC(=O)C(Oc2ccccc2C#N)C(C)C)[nH]n1 +COc1ccccc1CNC(C#N)c1ccccc1Cl +N#Cc1ccc(-c2ccc(Cl)c(Cl)c2)nc1N +CC(C)CC(O)CNC(=O)Nc1ccc2[nH]ccc2c1 +Cc1cccc(CN2CCN(C(=O)Cc3ccc(C)nc3)CC2)c1 +CC1CCCC(C)N1C(=O)CCc1ccc(N2CCCC2)c(N)c1 +COCCOC(=O)c1ccc(S(C)(=O)=O)cc1 +COc1ccc(OC)c(-n2nnc(CO)c2-c2ccccc2)c1 +COc1ccc(C(=O)Nc2cc(C)ccc2OC)cc1F +CCCNC(=O)N(Cc1ccccc1)Cc1ccco1 +O=C(Nc1cccc(N2CCNC2=O)c1)Nc1cccc2[nH]ccc12 +CC(C)(C)NC(=O)c1cccc(NC(=O)c2ccc(F)cc2)c1 +O=C(COc1cccc(C(=O)NC2CC2)c1)NCc1ccco1 +CC(C(=O)NCCc1nc2c(s1)CCCC2)n1cccc1 +Nc1ccccc1-c1nn2c(C3CCCO3)nnc2s1 +COc1ccc(-c2nnn(-c3ccccc3C#N)c2N)cc1 +Cc1cc(NC(=O)N2CCOC(C(N)=O)C2)n(Cc2ccccc2)n1 +CC1(C)Cc2cccc(OCC(=O)NCCOc3ccccc3)c2O1 +N#Cc1ccc2nc(COC3CN(C4CCCCC4)CC3F)[nH]c2c1 +COc1ccc(C(=O)NCC(=O)N2CCCc3ccccc32)cc1 +NS(=O)(=O)c1ccc(NS(=O)(=O)c2cc(F)cc(F)c2)cc1 +COc1ccc(C2CCN(c3ccc(C#N)cn3)C2)cc1 +CCCN(CC(=O)NC)C(=O)c1ccc(-c2nc(C)cs2)cc1 +CCNS(=O)(=O)c1cccc(C(=O)Nc2cccc(C(C)=O)c2)c1 +CSc1nsc(NC(=O)c2cc(F)ccc2F)n1 +C=CCCCN(C)C(=O)CCn1nc2ccccn2c1=O +O=C(Nc1onc2c1CCC2)c1cccc(Br)c1 +O=C(c1ccc(-n2cccn2)cc1)N1CCOC(Cc2ccccc2)C1 +COCCn1nc(C(=O)Nc2ccc(C(C)C)cc2)ccc1=O +CCc1ccc(OCC(=O)NCc2ccc(C#N)cc2)cc1 +CC(C(=O)NCC(C)(C)c1ccncc1)c1ccsc1 +CCn1ccc(CN(C)S(=O)(=O)c2ccc(CC(C)C)cc2)n1 +Cc1nn2c(CNC(=O)c3ccccn3)c(C)nc2s1 +CCn1cc(-c2nnc(-c3cccs3)o2)c(C)n1 +CC(C)Cc1ncc(Br)c(C2CC2)n1 +CC(C(=O)N(C)CC(=O)Nc1cccc2cn[nH]c12)n1cccn1 +CCCOCC(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1 +CN(C(=O)CN1CCOc2ccc(N)cc21)C1CCCCC1 +COCCN(CC(C)C)C(=O)c1cc(-c2ccncc2)on1 +C#CCOCC1CCN(C(=O)Nc2cccc(C)c2)CC1 +Cc1c(-c2ccccc2)nn(C)c1NC(=O)N1CCOCC(O)C1 +Clc1ccc(Cn2nnc(-c3cccnc3)n2)cc1Cl +CN1C(=O)Cc2cc(NC(=O)c3ccc(C#N)cc3)ccc21 +CS(=O)(=O)N1CCCc2cc(C(=O)NCCO)ccc21 +CCCNC(=O)CSc1nnnn1-c1ccc(C)cc1 +COCCC(=O)N1Cc2cnc(Cc3ccc(OC)cc3)nc2C1 +Nc1nccnc1C(=O)NCCCn1ccc2ccccc21 +CCn1c(SCC(N)=O)nnc1C1Oc2ccccc2OC1C +Cn1nc(C(=O)N2CCCC2)cc1NC(=O)CCc1ccccc1 +CC1CC(Sc2nnc(-c3ccc(Cl)cc3)n2C)C(=O)O1 +COc1ccc(-c2csc(C(N)c3ccncc3)n2)cc1 +COc1ccc(Cl)cc1-n1nnc(C#N)c1-c1cccnc1 +CCNC(=O)c1ccc(NC(=O)NCCc2ncc(C)s2)c(C)c1 +COc1ccc(N(C)C(=O)C2CC(=O)N(CC(F)(F)F)C2)cn1 +CCc1nc(CNc2ccccc2CN2CC(C)OC(C)C2)cs1 +O=C(NCCCN1CCOCC1)c1cc(-c2ccco2)on1 +CNC(=O)c1cccc(NC(=O)CNCc2ccccc2Cl)c1 +CC1Cc2cc(N)ccc2N1C(=O)C1CCCCO1 +Cc1noc(C)c1S(=O)(=O)NCc1cccc(C(N)=O)c1 +Cc1cc(C)cc(NC(=O)CSc2nnc3ccccn23)c1 +Cn1cc(CN2CCN(C(=O)c3ccco3)CC2)ccc1=O +O=S(=O)(NC1(CO)CCCCC1)c1cncc(F)c1 +Cn1c(-c2ccccc2)cnc1S(=O)(=O)Cc1ccc(C#N)cc1 +C=CCNC(=O)c1ccc(NC(=O)c2cc3c(s2)CCC3)cc1 +CCN(CC)S(=O)(=O)c1cc(Cl)cc(Cl)c1 +Fc1ccc2c(c1F)C(c1cnn3ccccc13)NCC2 +CCN(C(=O)C(C)OC)C(c1ccc(Cl)cc1)c1ccccn1 +CC=CCn1c(=O)c2c(nc3n(C)c(C)cn23)n(C)c1=O +CCS(=O)(=O)NCCCNC(=O)c1ccccc1O +COCc1ccccc1CNS(=O)(=O)c1cc(C)ccc1F +O=C(NCCCn1cncn1)c1ccc2c(c1)OCCO2 +CCN(CC)C(=O)c1c(-c2ccccc2)c[nH]c1C +CCN(CC)C(=O)Nc1ccccc1C(=O)NC1CCCCC1 +CC(=O)NCCOc1cccc2ccc(=O)n(C)c12 +Cc1csc(NC(=O)c2nccc3c(N)c(Cl)ccc23)n1 +Cc1ccc(C)c(C(N)c2cccn(C3CCCC3)c2=O)c1 +CCOC(=O)c1csc(C(C#N)C(=O)Nc2cccnc2)n1 +CC1CCCN(C(=O)C2CC(=O)N(C)C2c2cccc(Cl)c2)CC1 +CCCCNC(=O)Cn1cnc2c(cnn2-c2ccccc2C)c1=O +NC(=O)c1ccc(NC(=O)c2csc(-c3ncccn3)n2)cc1 +Cn1cc(CNc2ccc(CCO)cc2)c(-c2ccncc2)n1 +CC1(NC(=O)C2CC=CCC2)Cc2ccccc2C1 +COc1ccccc1NC(=O)N1CCCC1c1nc(C)no1 +CCc1ccc(NC(=O)Cn2ccccc2=O)cc1 +Nn1c(COc2ccccc2)nnc1SCC(=O)NC1CCCC1 +Cc1ccc(C)c(OCCCC(=O)Nc2nccs2)c1 +CCN(Cc1ccccc1Cl)C(=O)c1ccc(C(=O)OC)cc1 +Cc1cc(C)c2c(c1)C(Nc1ccc3nnc(C4CC4)n3n1)CCO2 +COc1cccc(OCC(=O)Nc2ccc(Cl)cc2N)c1 +Cc1ccc2nc(Nc3cccc(S(C)(=O)=O)c3)[nH]c2c1 +CCC1CN(CCn2cccn2)CCN1CC(O)c1ccccc1 +NC(=O)c1ccc(C#CCNC(=O)c2ccc3ccccc3c2)cc1 +Cc1cc(F)c(S(=O)(=O)N2CCN(CCO)CC2)cc1F +CCN(CC)C(=O)NCCc1ccc(-c2csc(C)n2)s1 +O=C(NCCN1CCc2ccccc21)c1cnn2cccnc12 +Cc1nc(C)c(CC(=O)N2CCCN(S(C)(=O)=O)CC2)s1 +Nc1cc(-c2csc(-c3ncc[nH]3)n2)ccc1O +O=C(CCC(=O)NCCC1=CCCCC1)N=c1[nH]nc2ccccn12 +CCCS(=O)(=O)N1CCC(Oc2cccnn2)CC1 +CC(C)c1nnc(CCOc2ccccc2N)s1 +CNc1nnc(-c2nn(-c3ccccc3)c(C)cc2=O)s1 +CCCNS(=O)(=O)c1ccc(N2C(=O)CCS2(=O)=O)cc1C +CCC1(C(=O)NCC(=O)NCc2ccc(OC)cc2)COC1 +CCn1ccc(CN(C)C(=O)c2ccc3c(c2)OCO3)n1 +Cc1ccccc1CN(C)C(=O)CSc1nnc(CO)n1C1CC1 +Cc1ccccc1C(=O)Nc1ccc(NC(=O)C2CCCO2)cc1O +COC(=O)c1occc1CN1CCN(C(=O)c2cc(C)no2)CC1 +CCC1c2ccsc2CCN1C(=O)NCCNC(C)=O +CN(C)C(=O)c1cc(NC(=O)N(C)CC2CCC2)ccn1 +CCC(C)OCC(=O)Nc1cc(Cl)ccc1N +CC(C)(CNC(=O)C#Cc1ccccc1)c1ccncc1 +COc1ccccc1NCc1nnnn1-c1ccc(C(F)(F)F)cc1 +CCOc1ccccc1NC(=O)c1nccnc1N +O=C(COc1ccc(Cl)cc1Cl)NC1CCCOC1 +Cc1ccc(CN2CCN(CC(=O)NCc3ccccc3)C2=O)cc1 +O=C(CC1C(=O)Nc2ncnn21)Nc1ccc(F)c(F)c1 +COc1cc(OC)cc(C(=O)NCc2cc(C)nc3ccccc23)c1 +CC(C)COC1CCN(C(=O)c2cnccn2)CC1 +Cc1cc(NC(=O)CNC(c2ccccc2)c2ccc(F)cc2)no1 +Cc1noc(C)c1S(=O)(=O)Nc1ccc(OC(F)F)cc1 +COc1ccc(CNC(=O)CCc2ccsc2)c(OC)c1 +COc1ccc(-c2noc(N)c2-c2cc(OC)c3c(c2)OCO3)cc1 +Cc1ccc(C)c(N2CC(c3nc(C)no3)CC2=O)c1 +Cn1cnnc1CCNC(=O)c1sccc1-c1ccccc1 +CCN1CCN(C(=O)c2nccc3c(N)cccc23)CC1 +COC(=O)CCS(=O)(=O)NCc1ccccc1Br +CC1CC1C(=O)NCc1cccc(NC(=O)NCc2ccncc2)c1 +Nc1ccc(-c2nc3cc(Cl)ccc3n2CCO)cc1 +COc1ccc(Oc2ncccc2NC(=O)NC(C)CO)cc1 +CCC(C)NC(=O)C(C)NCc1cc(F)ccc1F +C=CCNC(=O)c1ccc(NC(=O)C2CCCO2)cc1 +CCOC(=O)C(C)Nc1ccc(N(C)C(C)=O)cc1 +CCn1cnnc1CNC(=O)c1ccccc1C(=O)c1ccccc1 +COc1ccc(C(C)NC(=O)c2ccc(NC(C)=O)cc2)cc1OC +Cc1ccc(S(=O)(=O)CCC(=O)N2CCNC(=O)C2(C)C)cc1 +CCC(OC)C(=O)Nc1nc2c(OC)cccc2s1 +CC(=O)NCC(=O)Nc1ncc(Cc2ccc(Cl)cc2C)s1 +CCCOC(=O)N1CCCC2(C1)C(=O)N(C)c1ccccc12 +CC(=O)c1ccc(NC(=O)C(C)Oc2ccccc2C#N)cc1 +CC(Sc1ncc2ccccn12)C(=O)NC1CCCCC1 +NC(=O)c1ccc(C(=O)Nc2ccc(Cl)cc2F)cn1 +Cn1ccnc1C(NC(=O)Nc1cccc(Cl)c1F)C1CC1 +Nn1c(SCc2ccon2)nnc1-c1ccc(Cl)cc1 +COc1ccc(C(O)CNc2ccc(F)cc2)cc1 +COC(=O)Cn1cc(C#N)c2cc(Br)ccc21 +O=C(Nc1ccc(F)cc1F)N1CCc2c(nc[nH]c2=O)C1 +CCC(=O)c1ccc2c(c1)N(CC(=O)OC(C)C)C(=O)C(C(C)C)O2 +CC(=O)c1sc2ncn(C3CCCCC3)c(=O)c2c1C +CCOCC(=O)Nc1cc(C)nn1Cc1ccccc1 +CCc1n[nH]c(SCC(=O)NCc2sc(C)nc2CC)n1 +CC(=O)NCC1CCN(C(=O)c2cc3c(s2)CCC3)CC1 +CN(Cc1ccccn1)C(=O)NCc1cccc(F)c1 +O=C(C1CCCCCC1)N1CCC(n2cc(CCO)nn2)CC1 +CC(=O)NCC(=O)NCC(C)(O)c1ccccc1Cl +CC(C)(CNC(=O)c1ccc2[nH]c(=O)[nH]c2c1)c1cccs1 +Cc1ccc(Cl)c(OCC(=O)NCc2ccncc2)c1 +COc1cc(C2CC(=O)Oc3[nH]nc(-c4ccccc4)c32)ccc1O +CC(C(=O)Nc1nccs1)N1CCC(CN2CCOCC2)CC1 +COC(=O)c1ccc(C(=O)N(CCC(N)=O)c2ccccc2)s1 +Fc1cc(F)c2c(c1)CCNC2CC1CCOCC1 +COCCc1nsc(NC2CCN(c3ccc(C#N)cn3)CC2)n1 +CCn1ncnc1C1CC(=O)Nc2c1c(-c1ccccn1)nn2C +CC1CN(CC2CCCN2C(=O)C(C)CC2CCCC2)CC(C)O1 +CC(C)CNS(=O)(=O)c1ccc(C(=O)Nc2ccccc2)cc1 +O=C(Cc1cccc(Br)c1)NCCc1ccc(O)cc1 +CC(C)c1nn(-c2ccc(F)c(F)c2F)c2c1CNCC2 +COc1ccc(NC(=O)C2CCCN(C(=O)N(C)C)C2)c(OC)c1 +CCC(C)C(C(=O)NCc1ccccn1)N1Cc2ccccc2C1=O +CCCCNC(=O)C(C)Sc1ccc2c(c1)OCCCO2 +COc1ccc(NC(C)=O)c(NC(=O)CCn2cc(C)cn2)c1 +CC1CN(C(=O)c2ccn(COc3ccccc3Cl)n2)CC(C)O1 +CCCCC(NC(N)=O)C(=O)NCC1CCCCO1 +CCC(CC)NC(=O)c1ccc(Cl)cc1N1CCCC1=O +CC1CN(C(=O)c2ccc(F)cc2Br)CC(C)O1 +COc1cccc2c1C(c1cnccc1Cl)NCC2 +CCn1cc(Br)cc1C(=O)NCCC1CCCO1 +COc1ccc(C(NC(=O)Cc2cn3ccsc3n2)C(C)C)cc1 +Cc1ccc(-c2ccc(SCC(=O)N3CCCC3)nn2)cc1 +COC1CCN(C(=O)c2nc3ccccc3s2)CC1 +COc1cc(OC)cc(C(=O)Nc2cccc(-n3cnnc3)c2)c1 +Fc1ccccc1OCCNc1nccc(-c2cccnc2)n1 +NC(=O)C1CC(=O)N(CCc2ccc(F)cc2)C1 +Cc1[nH]nc(-c2cc(Br)ccc2F)c1N +CC(NC(=O)NCc1cnn(C)c1)c1ccccc1Cl +Cc1ccc(N)cc1S(=O)(=O)NCCC(F)(F)F +CCCOc1ccc(NC(=O)CNC(C)=O)cc1Cl +CC(C)S(=O)(=O)N1CCN(c2ccccc2Cl)CC1 +CN(C)S(=O)(=O)c1ccc(=O)n(CC(=O)c2ccn(C)c2)c1 +COCC(O)CN(C)C(=O)c1cc2ccccc2cc1OC(F)F +Oc1ccc(-n2nnnc2SCc2nccn2C(F)F)cc1 +c1ccc(CN2CCN(Cc3nnc4n3CCCCC4)CC2)cc1 +CC(c1ccco1)N(C)C(=O)c1cccc2ccccc12 +CCCC(=O)Nc1cccc(NC(=O)C(C)(C)C)c1 +CC1COCC(C)N1C(=O)c1ccc2ccccc2n1 +CCN1CCN(C(=O)C2CCCN2C(=O)Nc2ccccc2)CC1 +CCC1CCCCN1C(=O)C(C)S(=O)(=O)c1ccc(OC)cc1 +N#Cc1c(NC(=O)c2ccncc2)sc2c1-c1ccccc1CC2 +Cc1ccc(S(=O)(=O)Nc2nnc(C(F)(F)F)s2)cc1 +COCC(O)CN(C)C(=O)c1cc(N2CCCC2=O)ccc1Cl +COCCn1c(CO)nc2cc(C(F)(F)F)ccc21 +CC1CC1NC(=O)NCC(O)c1ccc2ccccc2c1 +CC(=O)Nc1cc(NC(C)c2cnn(C(C)C)c2)ccc1Cl +COc1ccccc1OC(C)C(=O)Nc1ccc(C(N)=O)cc1 +Cn1ccc(NC(=O)c2ccc(Cl)cc2O)n1 +Cc1c(-c2noc(-c3ccccn3)n2)nnn1-c1ccccc1 +COc1cccc(OCC(=O)Nc2ccc(OC)c(N)c2)c1 +O=C(NCc1ccccc1COCC1CC1)c1cc2n(n1)CCCO2 +Cc1cc2oc(=O)cc(CSc3ncn[nH]3)c2cc1C(C)C +CCN(CC(=O)Nc1c(Cl)cccc1Cl)c1ccnc(C)n1 +Cc1ccc(C(C)NC(=O)c2ccc(C#N)cn2)cc1F +CCc1c(C(=O)Nc2cc(F)ccc2OC)cnn1CC(C)C +CC(C)NC(=O)C1CN(c2nc3ccccc3s2)C1 +CCc1cc(N2CCC(=O)CC2)nc(-c2ccc(C)cc2)n1 +Cc1cc(C2CCCN2S(=O)(=O)c2cccc(C#N)c2)no1 +COc1ccc(OC)c(-c2ccc(C(N)=O)c(N)n2)c1 +Cc1cc(C)n(S(=O)(=O)c2cc(Br)c(C)cc2C)n1 +COc1cccc(S(=O)(=O)CC(=O)Nc2ccc(Cl)cc2)c1 +COC(=O)c1ccc(C(=O)Nc2ccc(NC(C)=O)cc2)cc1 +COc1ccc(-c2n[nH]c(C)c2NC(=O)c2ccccc2F)cc1 +CC(=O)NCCCCCC(=O)N1CCc2cc(F)ccc2C1 +COc1ccc(CCC(C)NC(=O)C(C)(C)n2cncn2)cc1 +CC(C)CSc1nc2c(cc1C#N)C(=O)CCC2 +COCCN1CCN(C(=O)c2cccnc2C)CC1=O +Cc1cccc(OC(=O)Cn2c(C)c(C)sc2=O)c1C +NC(=O)CCCNC(=O)Cc1ccc2c(c1)OCCO2 +CC1CC1C(=O)Nc1ccc(N2CCOCC2)c2nonc12 +CN(C)c1ccc(NC(=O)CC2CCCCC2)nc1 +Cc1nc(C(C)(C)NC(=O)c2coc3ccccc23)sc1C +Fc1cccc(-c2nc(-c3cn(-c4cccc(F)c4)nn3)no2)c1 +Cc1cc(N)c(C)c2c1OC(c1ccccc1)C(=O)N2 +C=CCN(Cc1nc(-c2cccc(C)c2)no1)C(=O)c1ccccc1 +CCOC(=O)c1cc(=O)c2cc(Cl)ccc2n1C +CNS(=O)(=O)c1cccc(C(C)NC(=O)NCc2cccnc2)c1 +Cn1ncc(Cl)c1-c1nc(C2CCOC2)no1 +CC(=O)Nc1nc(C(=O)N2CCN(c3ccc(F)cc3)CC2)cs1 +CCOC(=O)c1cn2nc(-c3ccc(OC)c(OC)c3)cc2nc1C +CC(C)CCN(C)C(=O)c1cc(S(C)(=O)=O)ccc1Cl +CCOC(=O)c1coc(N(C)Cc2nncn2C(C)C)n1 +COc1ccc(-c2ccc(N)nc2)cc1C(F)(F)F +Cc1nc(C(=O)Nc2sccc2C(=O)NC2CC2)c2ccccn12 +COC(=O)C1CCN(C(=O)Cc2cccc(Br)c2)CC1 +COc1ccc(-c2[nH]c(=O)c(C#N)c3c2CCC3)cc1O +COCc1nc(-c2ccc(OC)cc2)sc1C(C)(C)O +FC(F)Oc1ccc(Br)cc1Cn1ccnc1 +CCN(CC(=O)OC)C(=O)c1c(C)oc(C)c1C +CC(C)Nc1ncccc1C(=O)Nc1nncs1 +CC(CS(=O)(=O)N1CCNCC1)C(=O)NC(C)c1ccccc1 +CCOC(=O)c1sc2nc(-c3ccco3)ccc2c1N +COc1ccc(C(=O)Nc2onc3c2CCC3)cc1OC +Cc1ccc(C(NC(=O)Cc2nc3ncccn3n2)C2CC2)cc1 +O=C(Nc1cccc(NC(=O)c2cccc(F)c2)c1)c1ccncc1 +Cn1ccnc1Sc1ccc(NC(=O)c2ccc(=O)[nH]c2)cc1 +O=C(Nc1ccc2oc(=O)[nH]c2c1)c1ccc2cc[nH]c2c1 +CC(C)c1ccc(CN2C(=O)C(C)(C)CS2(=O)=O)cc1 +Cc1ccn2c(=NC(=O)C(C)Oc3ccc(C#N)cc3)[nH]nc2c1 +Cc1ccc(C(C)NC(=O)NCC2CCOC2)cc1 +CC1CCC(C#N)(N(C)C(=O)C(C)N2CC(C)OC(C)C2)CC1 +CS(=O)(=O)N1CCCC(C(=O)N2CCCCC2)C1 +Cc1nc(-c2cccs2)c(CC(=O)NCC(C)C)s1 +O=C(CC1(O)C(=O)Nc2ccc(Cl)cc21)c1cccc(Cl)c1 +Cc1csc(N2CCN(C(=O)Nc3ccc(F)c(C#N)c3)CC2)n1 +CCC(=O)NC1CCCN(C(=O)c2ccc(F)nc2)C1 +Cc1cc(N2CCCC2)nc(-c2ccccc2O)n1 +COCCSc1nc2ncc3c(n2n1)CCCC3=O +CCNC(=O)N1CCC(NC(=O)CCCc2cc(F)ccc2F)C1 +Cc1nc(SCC(=O)NCc2ccccc2)c(C#N)c(C)c1C +CN(Cc1nccn1C(F)F)C(=O)Nc1ccc(F)cc1Cl +COc1ccc(N2C(=O)C(OC)C2c2ccc3c(c2)OCO3)cc1 +O=C(CCCn1cncn1)N1CCCCCC1C=Cc1ccccc1 +CCOC(=O)C(Cc1ccccc1)N(C)C(=O)c1cccc(C)n1 +O=C(c1ccc2oc(=O)n(Cc3ccccc3)c2c1)N1CCCCC1 +O=C(NCc1cn2cc(Br)ccc2n1)NCC1CCC1 +O=C(c1cn(Cc2ccccc2)nn1)N1CCN(C(=O)C2CC2)CC1 +N#CC1(C(=O)Nc2ccc(-c3nnc4n3CCCC4)cc2)CCCC1 +Cc1cc(NC(=O)CNc2cc(C#N)ccc2C)no1 +O=C(COC(=O)c1ccc[nH]c1=O)Nc1ccc(OC(F)F)cc1 +CC(NC(=O)Nc1cccc(C(=O)NC2CC2)c1)c1ccc(F)cc1 +Cc1ccc(CNC(=O)c2ccc3oc(=O)n(C)c3c2)cc1 +CC(C)(CNC(=O)c1cc2cc(F)ccc2[nH]1)c1ccncc1 +Cc1nc(C2CCCN(C(=O)CCc3cccs3)C2)no1 +O=C(Nc1cccc(F)c1)C1(c2ccccc2)CC1 +CC(NC(=O)N1CCN(Cc2ccccc2F)CC1)c1nncn1C +Cc1noc(C)c1S(=O)(=O)NCc1ccc(Br)cc1 +O=C(NCCNc1ncccc1C(F)(F)F)c1cnccn1 +O=C(Nc1ccccc1C(F)(F)F)C1CC(O)=Nc2nncn21 +Cn1cccc(NC(=O)C2(c3ccc(F)cc3)CCCC2)c1=O +CC(NS(C)(=O)=O)C(=O)N(C)Cc1ccsc1 +COc1cccc(-c2cncc(C(=O)NCc3ccc(F)cc3)c2)c1 +O=C(CC1C=CCC1)NCC1(c2ccccc2)CC1 +CC(C)CCn1nc(CNc2ccc(Cl)cc2)[nH]c1=O +CSc1nnc(N)n1C(C)C(=O)Nc1ccc(F)cc1 +O=C(NCC1CCCO1)c1coc2nc3ccccc3nc12 +O=C(COCc1ccccc1Cl)Nc1ccc(-c2nnco2)cc1 +CCCCNC(=O)NCCc1cccc(OC)c1O +N#Cc1cccc(C(=O)N2CCN(C(=O)c3ccc(O)cc3)CC2)c1 +O=C(CSc1ccc(Cl)cc1)OCC(=O)c1ccc[nH]1 +O=C(NCC(O)c1ccccc1)c1cc(C2CC2)nc2ccccc12 +CC(C)n1cc(N)cc1C(=O)OCC1CCCO1 +Cc1nc(N)nc(C)c1CC(=O)N1CCC(c2cc(=O)[nH]cn2)CC1 +O=c1oc2ccc(F)cc2cc1-c1nc(-c2ccccc2)no1 +CC(=O)Nc1ccc(NC2=NS(=O)(=O)c3ccccc32)cc1 +Cc1cc(C(=O)NC2CC2)c2cc(Br)ccc2n1 +CCCNC(=O)C(C)Sc1nc(C2CC2)nc2ccccc12 +Cn1nccc1C(=O)Nc1nc(Cc2ccccc2)cs1 +NC(=O)Cn1c(-c2nc(-c3ccccc3F)no2)cccc1=O +COc1cccc(C(=O)NCCCC(=O)NC2CC2)c1F +CCc1ccccc1OCCN(C)C(=O)c1ccc2c(c1)OCO2 +Cn1nnc2c(SCC(=O)c3ccc(Cl)cc3)ncnc21 +CC(C)Nc1nc(-c2ccccc2)nc2c1CCN(C(=O)CC#N)CC2 +O=C(NCC#CCOc1cccnc1)c1ccc(=O)oc1 +CCCCNC(=O)C1CCCN(C(=O)COCC)C1 +Cc1cccc(CN2CCN(C(=O)c3c(F)cccc3F)CC2)c1 +Cc1ccc(NC(=O)COC(=O)c2ccco2)cc1 +Cc1cccc(C)c1OCCNC(=O)c1cnc(C2CCCO2)s1 +CC(=O)C(C)n1nc(CO)cc1-c1ccc(F)c(F)c1 +CCOc1cc(S(=O)(=O)NCc2ccccc2)ccc1Cl +Cc1ccc(C(=O)N(C)C)cc1NCc1noc(-c2ccoc2)n1 +CNC(=O)c1ccsc1NC(=O)c1ccc(Br)cc1 +CC1COCC(C)N1c1nn2cc(-c3ccccc3)nc2s1 +CCCCS(=O)(=O)NCC1CCN(C(=O)c2ccoc2)CC1 +COc1ccc(CNC(=O)COC(=O)c2cc3ccccc3o2)cc1 +O=C(Nc1cccc(C#Cc2ccccn2)c1)C1CC2CCC1O2 +N#Cc1cc(F)ccc1NC(=O)NCc1ccco1 +Cc1cc(=O)n(CC(=O)NCc2ccc3c(c2)OCO3)cn1 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc2[nH]nnc2c1 +CCc1cc(OC(=O)CCNC(=O)c2ccco2)ccc1Cl +CSc1cccc(NC(=O)C2CCCN(C(N)=O)C2)c1 +CCCOCC(=O)NC1CCCC1Cc1ccccc1 +Cc1cc(NC(=O)c2ccc(F)cc2Br)on1 +CCNC(=O)c1cnc(-c2cccc(Cl)c2)nc1N +CCc1ccc(OCC(=O)Nc2cc(NC(C)=O)ccc2OC)cc1 +CC(=O)N(CCc1ccccc1)Cc1nc(-c2ccsc2)no1 +CN(Cc1ccc(F)cc1)C(=O)NCc1cnn(-c2ccccc2)c1 +CS(=O)(=O)N1CCCCC1C(=O)Nc1ccc(C#N)c(Cl)c1 +N#Cc1ccc(N2CCC(C(=O)N3CCOCC3)CC2)nc1 +CC(C)c1nc(S(=O)(=O)N2CCc3sccc3C2)c[nH]1 +CC1=C(C(=O)N2CCN(C)CC2)C(c2ccco2)n2ncnc2N1 +Cc1c(C(=O)N2CCN(S(N)(=O)=O)CC2)cnn1C +CC(C)C(=O)N1CCC(C(=O)Oc2ccc(Cl)cc2)CC1 +CN(CCC#N)C(=O)C1CCN(C(=O)c2ccoc2)CC1 +OCc1ccc(COc2ccc(Br)cc2)o1 +Cc1nc(Nc2ncnc(N3CCCCC3)c2N)sc1C +COc1ccc(CN(C)C(=O)CCn2ncc3c(C)cccc32)cc1 +CCc1cc(C(=O)N2CC(=O)Nc3ccccc32)sc1C +CCCC(=O)NCC(O)c1ccc(OCC)cc1 +NC(=O)c1ccc(C2CN(C3CCOCC3)CCO2)nc1 +COCCNC(=O)Cn1nc(C)c2ccccc2c1=O +CN(C)C(=O)c1ccc(C(=O)OCC(=O)NC2CCCCC2)cc1 +CC1CN(C(=O)Nc2ccc3c(c2)COC3)CC(c2ccccc2)O1 +COCC(C)OC(=O)c1nc(C2CC2)n(-c2ccccc2)n1 +Cn1cc(N2CCN(CC3=Cc4ccccc4OC3)CC2=O)cn1 +CCCC(=O)N(Cc1cc2ccc(C)cc2[nH]c1=O)C(C)(C)C +CCOc1ccc(-c2cc(C(=O)OC)nc(N(C)C)n2)cc1 +CN(CC(O)COCc1ccccc1)C(=O)c1cc(Cl)ccc1O +O=C(Cc1csc(-c2ccncc2)n1)NCc1ccco1 +CC1(CCC(=O)Nc2ccnn2C2CCCCC2)CC1 +CCc1noc(CC)c1CC(=O)Nc1ccc(N(C)C)nc1 +CCOc1ccc(CN(C)C(=O)C(C)n2cncn2)cc1OC +Cc1nc(NCCNC(=O)c2ccco2)cc(-n2cccn2)n1 +CC(C)OC(=O)C(C)n1nc(C#N)cc1-c1cccs1 +Cc1ncsc1CCOC(=O)c1cccc(N2CCNC2=O)c1 +Cn1cc(CN2CCN(Cc3cccc(F)c3)CC2)ccc1=O +CCCCCOc1ccc(-c2cc(C(N)=O)nc(N)n2)cc1 +Cn1ccc(C(=O)Nc2nc3c(s2)CCCC3)n1 +Cc1ccccc1CS(=O)(=O)Nc1ccc(F)c(F)c1 +COc1ccc(CCc2nnc(NC(=O)c3ccco3)s2)cc1 +COCC(=O)N1CCCN(Cc2ccc(C(F)(F)F)cc2)CC1 +CCN(CC)C(=O)CCC(=O)Oc1cc(C)ccc1Cl +CCn1nc(C(C)C)cc1C(=O)N(C)Cc1snnc1C +CC(C)c1ccc(NC(=O)c2cnn(C)c2N)cc1 +Cc1nscc1C(=O)N(C)Cc1ccc(F)cc1 +CC(C)Oc1ccccc1CC(=O)NC(C(N)=O)C(C)(C)C +CC(C)(C)c1nc(CSc2nc(N)cc(=O)[nH]2)cs1 +COc1c(Cl)cc(Cl)cc1CN1CCOC(C(N)=O)C1 +CCn1cc(C(=O)Nc2c(C(=O)N(C)C)nn(C)c2C)c(C)n1 +COc1cc(C(=O)NCc2c(C)noc2C)nc(OC)n1 +CC(=O)c1cccc(NC(C)C(=O)NCC(C)C)c1 +O=C(CCn1cncn1)N1CCN(CC2CC2)c2ccccc21 +O=C(NCCOc1ccccc1Cl)c1cc2c(cn1)OCC2 +CCNc1oc(COc2c(C)cccc2C)nc1C#N +c1ccc(CN(Cc2ccccc2)Cc2ccncc2)cc1 +CS(=O)(=O)N1CCCN(Cc2ccc(C#N)cc2)CC1 +c1cc(-c2nc(C3CCOCC3)nn2CC2COCCO2)n[nH]1 +CC(=O)N1CCc2cc(C(=O)N3CCCS3(=O)=O)ccc21 +CC(C)(C)OC(=O)N1CCC(OC(=O)CC2C=CCC2)CC1 +COc1ccc(SCC(=O)Nc2cc(F)c(OC)c(F)c2)cc1 +O=C(CCC1CCCC1)N1CCC(c2nnc3n2CCC3)CC1 +CC(=O)N1CCC(NC(=O)Nc2cc(-c3ncco3)ccc2C)C1 +CC1(C)C2CC=C(COC(=O)c3cc4c([nH]c3=O)CCCC4=O)C1C2 +Cc1cccc(N2CC(C(=O)NCc3ccccc3Cl)CC2=O)c1 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccccc1-n1cnnn1 +Cc1ccc(F)cc1NC(=O)N1CCCC(C(=O)N2CCOCC2)C1 +COCCCNC(=O)c1cn(-c2ccc(Br)cc2)nn1 +N#Cc1c(-c2ccccc2F)c2c([nH]c1=O)CCC2 +CC(C)CC(C)(NC(=O)Cc1csc(-c2ccoc2)n1)C(N)=O +COc1cc[nH]c(=NS(=O)(=O)c2sccc2Br)c1 +CC(NC(=O)c1ccc(C(=O)N(C)C)cc1)c1ccc(F)c(Cl)c1 +CC(C)(C)c1ccc(Cn2ccc(N)cc2=O)cc1 +CCCOCC(=O)N=c1[nH]c2ccccc2n1C1CCCC1 +Cc1c(C(=O)N(C)C(C)C(C)(C)C)sc2ncn(C)c(=O)c12 +CC1CCC(C(N)=O)CN1C(=O)c1ccc(OCC2CCCO2)cc1 +Cc1ccc(C(=O)N(C)C(C)c2ccc(S(C)(=O)=O)cc2)c(C)c1 +Cc1ccc(NC(=O)c2cc(S(=O)(=O)N(C)C)c(C)s2)cc1 +CCOc1ccccc1OCC(=O)NCc1cccc(Cl)c1 +Cn1ccc(CN2CCOC(c3nccs3)C2)cc1=O +CCNC(=O)c1c(C)nc(N)nc1Cc1ccc(Cl)cc1 +O=C(NCc1ccc(C(=O)N2CCCC(O)C2)cc1)c1cccs1 +CC(=O)Nc1cc(NCc2ccccc2N2CCOCC2)ccc1F +Cc1nc(C2COCCN2Cc2ccccn2)cs1 +O=C(c1cccc(OC(F)F)c1)N1CCN(c2ncccn2)CC1 +COC(=O)c1ccsc1NC(=O)CC1CCCCC1 +Cn1nc(C(=O)Nc2ccc(-n3cnnn3)cc2)ccc1=O +CC(=O)Nc1ccccc1C=Cc1ccc2cccc(O)c2n1 +Cc1cnc(CSc2nnc(-c3cccs3)n2C)cn1 +O=C(Nc1cccc(F)c1)N1CCC(c2nc3ccccc3[nH]2)CC1 +CC1CCN(C(=O)NCc2ncn(C)n2)C(c2ccco2)C1 +Cc1ccc(NC(=O)CC2CCCCC2)cc1-n1cnnn1 +COc1ccc(F)cc1NC(=O)c1c(F)cc(F)cc1F +CC(C)CCNC(=O)CSc1nc2ccccc2[nH]1 +CC(NC(=O)NCc1ccc(Cl)cc1Cl)c1ccncc1 +CN(CC1CC1)C(=O)c1cnc(-c2ccccc2)nc1 +CCS(=O)(=O)c1ccc(-c2cc(C(=O)OC)[nH]n2)cc1 +COCCN1CC(C(=O)Nc2ccncc2)CC1=O +COc1ccc2c(c1)nc(-c1ccccc1)c(=O)n2CC#N +Cc1cccc(OC(C)C(=O)Nc2ccccc2N)c1C +Cc1ccc(-c2nc(C)c(C(=O)NCc3ccoc3)s2)o1 +COCCc1ccc(OS(=O)(=O)c2ccccc2F)cc1 +N#Cc1ccc(C(=O)NCC(O)c2ccc(C(F)(F)F)cc2)cc1 +Cc1cc(CS(=O)(=O)N2CCSc3ccc(N)cc32)no1 +COc1cc(C)c(S(=O)(=O)NCc2cccc(C)n2)cc1C +Cn1cc(C(=O)OCC2CC2(Cl)Cl)c(-c2cccs2)n1 +Cc1cccc(OCC(=O)N2CCC(c3nc(C(C)C)no3)CC2)c1 +Cc1ncc(CNc2ccn(-c3ncccc3Cl)n2)s1 +Cc1ccc(NC(=O)C(C)Sc2nc3c(c(=O)[nH]2)CCC3)cc1 +Cc1ccnc(NC(=O)c2cc(=O)c3cc(C)cc(N)c3o2)c1 +CCOc1cc(S(=O)(=O)Nc2cccnc2)c(OCC)cc1C +COCCCNC(=O)Cc1ccc(-c2ccccc2)cc1 +COCCCNC(=O)c1c(-n2cnnn2)sc2c1CCC2 +CNc1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1 +CN(CCOCC1CC1)C(=O)NC1CCc2c(O)cccc21 +O=S(=O)(NCC1(O)CCOCC1)c1ccc(F)cc1 +Cc1ccsc1CN1CCC2(CC(OCC3CC3)CO2)C1 +CCOc1ccc(-c2nc(CC(=O)N(C)CCC#N)cs2)cc1 +Cc1ccc(-c2nc(CN3CCN(C(=O)C4CC4)CC3)cs2)o1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)NCc1cccs1 +CCOc1ccc(CNC(=O)CSc2ccccc2)cc1 +O=C1CCN(S(=O)(=O)c2ccccc2F)CC1 +O=C(Cc1ccccc1)OCc1cc(=O)n2nc(C3CC3)sc2n1 +O=C(NCCNC(=O)c1ccco1)Nc1ccc(OC(F)F)cc1 +COc1ccccc1CN(C)C(=O)c1c(-c2ccccc2)noc1C +O=C(Nc1ccc2nc(C3CC3)sc2c1)c1csnn1 +CCCCNC(=O)Nc1ccc2nc(N3CCOCC3)sc2c1 +CCC(C)NC(=O)COC(=O)c1cccc(N(C)C)c1 +CC(C)Cn1nc(CC(=O)Nc2nncs2)c2ccccc2c1=O +O=C(NCCC(=O)N1CCc2ccccc2C1)NC1CCCCC1 +CC(C)N(C)S(=O)(=O)N1CCc2sccc2C1C +CC(=O)Nc1ccc(-c2nc(-c3ccncc3)no2)cc1 +CCc1ccc(C(=O)N(Cc2cccn2C)C2CC2)cc1 +Cn1c(CCCNC(=O)c2ccn3nnnc3c2)nc2ccccc21 +COc1cccc(OC(C)(C)C(=O)n2ccnc2)c1OC +CC(=O)Nc1ccc(SCC(=O)Nc2nccs2)cc1 +CCC(CC)(CC)NC(=O)Nc1cccc(S(N)(=O)=O)c1 +Cc1ccc(OCCC(=O)OCc2cnn(C)c2)cc1C +CCOC(=O)Cc1nnc(NC(=O)c2scnc2C2CC2)s1 +COC(=O)c1ccccc1CN(C)C(=O)CCc1cccs1 +O=S(=O)(c1cccnc1)N1CC(c2nc(-c3cccs3)no2)C1 +Cc1cccc(C(=O)NCCCn2nc3n(c2=O)CCCC3)c1O +CC(=O)NC(C(=O)Oc1ccc(F)cc1)C1CCCC1 +CCN(CC)C(=O)CCCC(O)c1c(C)cc(C)cc1C +CC(NC(=O)c1cnn(-c2ccccc2)n1)c1cccs1 +O=C(c1ccco1)N1CCN(CC(O)COc2ccccc2)CC1 +Cc1ccccc1S(=O)Cc1ccc(C(=O)NC(C)C)o1 +COc1ccc(CCNC(=O)NC(C(N)=O)c2ccccc2)cc1 +CCOC(=O)NC1CCCN(CC(=O)Nc2cc(C)no2)C1 +O=C(Nc1ccc2c(c1)OCCO2)N1CCCC1c1ccccc1F +O=C(NCC(O)CO)Nc1sc2ccccc2c1Cl +COCCn1cnnc1SC(C)c1nc(C2CC2)no1 +CCC(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1 +N#CC(NC(=O)C1CC(=O)Nc2ccccc21)c1cccc(Cl)c1 +O=C(c1ccncc1)N1CC(OCc2cccnc2)C2OCCCC21 +COc1cc(C)ccc1OC(=O)c1ccc(F)nc1 +CCOC(=O)C(C)Nc1ncc(C(F)(F)F)cc1Cl +CCCCNC(=O)c1c(-n2cnnn2)sc(C)c1C +O=C(CCCNC(=O)c1ccccc1)Nc1cccc(-n2cnnc2)c1 +Cc1cc(C)n(C(C)C(=O)Nc2nc(C)c(C)s2)n1 +CCc1ccc(-c2csc(NC(=O)c3cc(C)no3)n2)s1 +COc1ccc(NC(=O)c2nccc3ccccc23)cc1 +O=C(NCCCO)c1nc(-c2ccc3cc[nH]c3c2)no1 +CCn1c(C)nnc1SCC(=O)c1cnn(C)c1 +CCC1CCC(CNC(=O)c2cc(C3CC3)[nH]n2)CC1 +Cc1ccc(-c2nc(C(=O)NCc3ccncc3)cs2)o1 +COc1ccc(NC(C)=O)cc1NC(C)C(=O)Nc1cc(C)no1 +Cc1ccc2c(CC(=O)N3CCC(C(=O)N(C)C)CC3)coc2c1 +CCOc1cc(NC(=O)c2ccnc(OC3CCC3)c2)ccc1OC +OCCN(Cc1ccccc1)Cc1nc2ccccc2n1C(F)F +CC(c1nc(C2CC2)no1)S(=O)(=O)c1ccccc1Cl +C=CCNC(=O)CSc1nnc(-c2ccccc2F)n1C1CC1 +CCn1cc(C#N)c(=O)n(CC(=O)N(C2CC2)C(C)C2CC2)c1=O +Cn1nnnc1-c1ccc(S(=O)(=O)N2CCCC2)cc1 +NC(=O)c1ccc(OCC(=O)Nc2ccc(-c3ncc[nH]3)cc2)cc1 +Cn1cc(C(=O)N2CCC(c3n[nH]c4ncccc34)CC2)cn1 +O=C(C1CC1)N1CCC(OCc2ccc(F)cc2)CC1 +Cc1sc2ncn(CC(=O)NCc3cccs3)c(=O)c2c1C +COCCN(CC(F)(F)F)C(=O)c1c(C)nn2c(C)cc(C)nc12 +Cc1ccc(OCC(CC#N)N2CCCCC2)cc1C +Cc1nnc(-n2nnc(C#N)c2-c2ccc3c(c2)OCO3)s1 +CCCC1CCC(NC(=O)CCC(=O)Nc2nccs2)CC1 +CCOC1CC(NC(=O)CCc2nc(C3CC3)no2)C12CCCCC2 +Cc1nc2nnc(C(=O)Nc3ccc(Cl)cc3)c(C)n2n1 +COc1cccc(OCC(=O)NCCc2ccccc2)c1 +CCc1nnc(NCc2cc(-c3cccnc3)no2)o1 +CNS(=O)(=O)c1sc(S(N)(=O)=O)cc1C(=O)OC +Cc1c(Cl)cccc1C1CCCn2nc(N)nc21 +CN(CCc1ccccc1)S(=O)(=O)c1ccc(C(N)=O)cc1 +CNC(=O)C1COC(=O)N1Cc1ccc(OC)cc1 +CCOC(=O)C1CCN(C(=O)Cc2ccc(F)cc2)CC1 +Cc1cc(=O)[nH]c(CCNc2ncnc3sc(C)c(C)c23)n1 +CC(=O)Oc1ccc(C(=O)N(C)c2ccccc2)cc1 +CC(C)C(C)NC(=O)CNC(=O)c1cccc(Br)c1 +Cc1noc(COC(=O)c2ccn(-c3ccccc3)n2)n1 +CC(=O)NC(C(=O)N1CC(c2ccc(F)cc2)CC1C)C1CCCC1 +O=C(Nc1nc2c(s1)CCC2)c1ccc2c(c1)OCCCO2 +COCCCNS(=O)(=O)c1cc(Cl)c(OC)cc1Cl +Cc1cc(C(C)NC(=O)CCC(=O)c2cccs2)c(C)s1 +CCCn1ncc(-c2cn(Cc3ccc4nonc4c3)nn2)c1C +COc1cccc2cc(C(=O)N(C)Cc3nccn3C(F)F)oc12 +COc1ccc(Cl)cc1NC(=O)c1cn(C)nc1C(F)(F)F +CC(CCc1ccccc1)NC(=O)c1ccc(=O)[nH]c1 +COc1ccc(CNC(=O)NCC(O)c2cccs2)cc1OC +COc1ccc(-c2noc(C(=O)NC(C)(C)C)c2N)cc1 +O=C(Nc1ccccc1N1CCOCC1)c1c(F)cccc1Cl +CN(CC(N)=O)C(=O)Cc1csc(-c2ccsc2)n1 +O=C(c1ccc2occc2c1)N1CCCC(CO)(CC2CC2)C1 +CC(=O)N1CCCC1C(=O)NCc1ccc(Cl)cc1Cl +CC(=O)OCCOc1cc2c(cc1Cl)OCO2 +O=C(Cc1coc2cc3c(cc12)CCC3)NCc1ccccc1F +Cc1nn(C)c(C)c1CNc1nc2ccccc2o1 +CCOC(=O)c1cnc2nc(C)ccc2c1NCc1ccco1 +CCOc1ccccc1CN(C)C(=O)Nc1cccc(NC(C)=O)c1 +O=C(CCNC(=O)c1ccc(Br)cc1)NCC1CCC1 +CCOc1c(OC)cc2c(c1Cl)C(C)NCC2 +Cc1cc(F)ccc1NC(=O)c1n[nH]cc1Br +Cc1cc(NC(=O)Cn2cnc3c(C)cccc3c2=O)ccn1 +CC(C)(C)c1nn2c(C(Cl)(Cl)Cl)nnc2n(N)c1=O +Cc1cncc(C(=O)N2CCC3(CC(=O)N(c4ccccc4)C3)C2)c1 +CCOC(=O)c1c(NC(=O)c2cc(C)n(CC)n2)sc(C)c1C +CS(=O)(=O)c1cccc(OS(=O)(=O)c2ccc(F)cc2F)c1 +O=C(CCSc1ccccn1)Nc1ccc(-c2csnn2)cc1 +O=C(CSc1ncccn1)N1CCN(Cc2ccccc2)CC1 +Nc1ccc(Br)cc1C(=O)N1CCCCCC1 +CCCc1[nH]ncc1C(=O)OCc1cn2ccccc2c1C#N +CCSc1ccc(C(=O)N(C(C)C)C2CCOCC2)cn1 +O=C(c1cscn1)N1CCCC(c2ccncn2)C1 +CCCn1c(N)c(N(CCOC)C(=O)C(C)(C)C)c(=O)[nH]c1=O +Cc1ccncc1NC(=O)NCCCOc1ccc(F)cc1 +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)NC(C)c1c(C)noc1C +C#CCN(Cc1ccc(C)cc1)C(=O)c1cc(S(N)(=O)=O)c(C)o1 +Cc1cc(Cl)c2nc(-c3ccncc3)c(N)n2c1 +COC(=O)Cn1c(CCO)nc2ccc(F)cc21 +Cc1nc(CSc2nnc(-c3ccccc3Cl)n2N)oc1C +O=C1CC(c2nc3cc(Cl)ccc3o2)CN1c1ccccc1 +COCC1CN(Cc2cccnc2)Cc2nn(C)cc21 +Cc1ccccc1N1CCN(C(=O)c2cc(C)n3nccc3n2)CC1 +Cc1ccc(OCc2cccc(C(=O)Nc3cc[nH]n3)c2)cn1 +CC(C)(CNC(=O)c1ccc[nH]1)CNC(=O)c1ccc[nH]1 +O=S(=O)(NCC1CCCC1O)c1ccc(Cl)c2ncccc12 +CN(CCO)C(=O)NC(CC1CCC1)c1ccccc1 +Cc1n[nH]c(C)c1N1CCN(Cc2ccccc2)CC1 +COc1ccc2c(c1)cc(CO)c(=O)n2CC(C)C +Cc1nccn1-c1ncccc1NC(=O)CCc1ccsc1 +CC(=O)NC1CCN(C(=O)NCCCCC(C)C)CC1 +O=C(CCC(=O)N1CCCS1(=O)=O)c1ccc(F)c(F)c1 +O=C(NCC1CN2CCCCC2CO1)C1CSc2ccccc21 +CCOc1ccc(CCNC(=O)c2cnc(N(C)C)nc2C)cc1 +CC(C)(C)OC(=O)N1CCC(c2nc3ccc(F)cc3cc2N)CC1 +CCC(=O)N1CCC2(CC1)CN(CC(CC)CC)C(=O)O2 +O=C(CNC(=O)c1ccc(F)cc1)NCc1ccc(Cl)cc1 +Cc1ccc(C(=O)CCC(=O)NC(C)CO)cc1C +CC(C)C(=O)Nc1nnc(S(=O)(=O)N2CCCC2)s1 +CC(C)N(C)C(=O)c1ccc(Br)c(Cl)c1 +CCCN1C(=O)C2CCC(=O)N2c2ccc(C(=O)NC(C)C)cc21 +COCCCN(C)c1nc2c(c(=O)[nH]c(=O)n2C)n1C +Cc1nc(Cn2sc3ccccc3c2=O)cs1 +COc1cc(OC)c(NC(=O)c2c(Cl)cnn2C)cc1Cl +CC1CN(C(=O)c2ccc(OCC3CCCO3)cc2)C(C)CO1 +CNC(=O)Cc1ccc(NC(C)c2nnc(-c3ccccc3)o2)cc1 +CCc1ccc2occ(CC(=O)Nc3cc(C)on3)c2c1 +CCCn1cnc(NC(=O)c2cn3cccc(C)c3n2)n1 +CC(O)CNC(=O)C(N)c1cc(F)cc(Cl)c1 +O=S(=O)(NCCC(O)c1ccco1)c1cccc(C(F)(F)F)c1 +CC(C)(C)OC(=O)N1CCC(C#N)(c2ccc(F)cc2F)CC1 +CC1(C)CC1C(=O)Nc1ccc(Oc2cccnc2)nc1 +CC(C)c1cc(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)n[nH]1 +COCCOCC(=O)Nc1cccc(C(C)C)c1 +O=C(NC1CCN(C(=O)C2CCC2)CC1)c1cccs1 +CCCc1nnc(NC(=O)N(C)Cc2ccccc2C)s1 +Cc1cc(C)n(CC(=O)Nc2cc(F)cc(F)c2)c(=O)c1C(N)=O +CNS(=O)(=O)c1ccc(NC(=O)c2ccsc2)cc1OC +COc1ccc(NC(=O)c2snnc2C)cn1 +CCOC(=O)c1ccc(CNC(=O)c2ccoc2)cc1 +CCCCCn1c(SC(C)C(C)=O)nc2c1c(=O)[nH]c(=O)n2C +Cc1cc(Cl)ccc1NCCC(=O)c1cccc(N)c1 +Cc1nc(Cn2cc(Cl)cn2)n(-c2ccc(F)cc2)n1 +O=C(Cc1ccc2cccnc2c1)c1ccc(O)cc1O +O=C(Nc1nccs1)N(CCO)Cc1ccsc1 +Cc1csc(N2CCCN(S(C)(=O)=O)CC2)n1 +Nc1cc2c(cc1Oc1ccccc1Br)NC(=O)C2 +Cc1nc(C(C)(C)NC(=O)Nc2ccccc2)no1 +CC1(C)CN(C(=O)c2ccc(-n3ccnn3)cc2)CC1c1ccccc1 +Cc1cc(C)c(NC(=O)c2ccc(=O)n(-c3ccccc3)n2)c(C)c1 +CN(CCOCC1CC1)C(=O)Cc1cccc(Cl)c1 +CC(C)c1nc(NCC(O)c2ccccc2)c2cnn(C)c2n1 +Cc1ccc(C(=O)C2CCN(C(=O)NCc3ccncc3)CC2)cc1 +Cc1nc(C(=O)N2CCN(C)CC2)nn1-c1ccccc1Cl +CCC(C)n1ncc(C(=O)OCc2nnc(C)n2C)c1C1CC1 +O=C(Cn1cnc2sccc2c1=O)NC(c1ccccc1)C1CC1 +CC(C)(C)OC(=O)N1CCC(Cn2c(CO)nc3ccccc32)CC1 +O=C(Cn1c(C2CCCCC2)nc2ccccc21)NC1CC=CC1 +Cc1cccc(NC(=O)CSc2ccc(-c3cccnc3)nn2)c1 +CCc1noc(CC)c1CC(=O)Nc1ccc(S(C)=O)cc1 +O=C(CNC(=O)c1ccc2cc[nH]c2n1)NCc1ccc(F)cc1 +CC(C)CNc1nc(-c2cc3c([nH]c2=O)CCCC3)cs1 +O=S(=O)(NCC1(c2ccccc2)CC1)c1ccc(F)c(F)c1F +Cc1cc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)n(C)n1 +Cc1n[nH]c(C)c1CCCNC(=O)Nc1ccc(F)nc1 +Cc1nc(=O)[nH]c(C)c1CCC(=O)Nc1n[nH]c2c(Cl)cccc12 +Cc1n[nH]c(C)c1CCC(=O)NCCCc1ccccc1 +COCCOC1CN(C(=O)C2CC23CCCc2ccccc23)C1 +N#Cc1ccc(CSc2nc(-c3cccnc3)n[nH]2)cc1 +O=C(Cc1ccc(O)cc1)Nc1ccc(Br)cc1F +Cc1ccc(C2CCCN2S(=O)(=O)N2CCc3ccccc3C2)o1 +O=C(NC(C(=O)Nc1ccccc1)c1ccccc1)C1CC1 +Cc1ccccc1CC(=O)Nc1cccc(C(=O)NC2CC2)c1 +CCC(=O)N1CCCN(C(=O)c2cn(C)nc2C(F)(F)F)CC1 +CC(=O)Nc1cc(C(=O)Nc2nc3ccccc3s2)ccc1F +COc1cccc(CC(=O)N2CCN(Cc3cc(C)oc3C)CC2)c1 +Cc1c(C(=O)N(C)Cc2ccsc2)oc2c1C(=O)CC(C)(C)C2 +COc1ccc(NC(=O)C2COc3ccccc3O2)cc1Cl +CC(C)(CO)n1c(-c2ccc(N)cc2)nc2ccc(F)cc21 +COC(=O)Cc1nc2c(Cl)cc(Cl)cn2c1N +Cc1cc(C(=O)NCCCn2nnc3ccccc32)cnc1C +O=C(OCc1ccccn1)c1ccccc1OCc1cscn1 +O=C(OCc1cc(-c2ccco2)on1)c1cccs1 +Cc1ccc(Cl)c2c1NCC(c1cccs1)C2 +Cc1cc(N)nc(SCC(O)COc2ccc(Cl)cc2)n1 +CN(CCCOc1ccccc1)C(=O)Nc1ccc(F)cc1C#N +Cc1nc(-c2cccc(F)c2)c(N)c(N2CCOCC2)n1 +COc1ccc(CC(=O)n2nc(N)c3ccccc32)cc1OC +Cc1oncc1C(=O)N1CCc2cnc(N(C)C)nc2C1 +COc1ccc(Nc2nc(-c3ccccn3)cs2)cc1N +CN(Cc1ccccc1N1CCOCC1)C(=O)c1c(F)cccc1F +Cc1c(C(=O)Nn2cnc3ccccc32)cnn1-c1ccncc1 +C#CCOc1ccc(F)cc1NC(=O)CCSc1ccccn1 +CNC(=O)c1cc(C)ccc1NC(=O)COCCOC +O=C(Nc1ccc(OC2CCCCC2O)cc1)C1(O)CCCC1 +Fc1cccc(Cn2ncc3[nH]c(-c4ccc(-c5ccn[nH]5)o4)nc32)c1 +Cc1nnc2n1CCN(c1ncnc3sccc13)C2 +FC(F)(F)c1ccnc(N2CCC(n3cnnc3)CC2)n1 +O=C(NCCN1CCOCC1)C1(c2ccc(F)cc2)CCCC1 +CN(C(=O)c1ccc2c(c1)OCO2)c1ccccn1 +CC(C)CC(CO)NC(=O)Nc1ncc(-c2ccccc2)s1 +COCc1ccc(C(=O)Nc2cccc(-n3nc(C)cc3C)c2)cc1 +O=C(NCCc1nnc2n1CCC2)C1CC1c1ccc2ccccc2c1 +CCN(CC)C(=O)CCC(=O)Nc1ccc2c(c1)oc(=O)n2C +CC(Oc1ccccc1)C(=O)NCCn1ccnc1-c1ncccn1 +CN(C)c1cc(CSc2ccc(C(=O)N3CCCC3)cn2)ccn1 +O=C(CCc1ccccc1)Nc1ccccc1C(=O)NC1CC1 +CCN(C(=O)CNc1cc(Br)ccc1Cl)C1CC1 +Nc1cccc(C(=O)CCC(=O)N2CCc3ccccc32)c1 +COc1cccc(OC)c1C(=O)NCCOc1ccc(F)cc1 +COc1ccc2c(c1OC)C(=O)N(c1nc[nH]n1)C2 +Cn1cc(NC(=O)c2cc3ccc(Cl)cc3n2C)cn1 +COc1cccc(C(=O)OCC(=O)Nc2ccc(C)cc2F)c1 +CCCS(=O)(=O)c1ccc(C)cc1C(O)CC +O=C(CN1C(=O)COc2ccccc21)N1CCCCC1 +CC(NC(=O)c1ccc(-n2ccnn2)cc1)c1ccc2c(c1)OCO2 +CC(C)OC(=O)c1ccc(NC(=O)c2cccnc2)cc1 +O=C(Nc1cccc(O)c1)c1cccc(NC(=O)C2CCCO2)c1 +COc1ccc2c(c1)CN(Cc1c[nH]nc1-c1cccs1)CC2 +COCc1cc(NC(=O)c2cnn(-c3ccncc3)c2C)ncn1 +CCC(C(=O)NCc1ccc2c(c1)OCCO2)c1ccccc1 +O=C(c1ccc(O)c(Cl)c1)N1CCN(Cc2ccccc2)CC1 +CC(=O)c1ccnn1-c1ccc(C(F)(F)F)cc1 +O=C(NCCc1c[nH]c2ccc(F)cc12)NC1CCCCC1 +COc1ccc(NC(=O)c2ccc(NC(C)=O)cc2)cc1Cl +Cc1ccc(C2COCCN2Cc2cnc(C3CCCC3)s2)o1 +COc1cccc(CNC(=O)CCc2nc(-c3cccnc3)no2)c1 +CCc1nnsc1C(=O)N1CCc2ccccc21 +CCc1nnc2n1CCN(C(=O)C1CCCC(C(F)(F)F)C1)C2 +CCCC(=O)Nc1cc(C)nn1-c1nc(-c2ccco2)cs1 +O=C(CCCNC(=O)C1CC1)NC1CCCNC1=O +CC(=O)c1ccc(OCC(=O)Nc2cc(Cl)ccc2N(C)C)cc1 +O=c1ccc(-c2ccc(F)cc2)nn1Cc1noc(C2CC2)n1 +Cn1cccc1CNC(=O)c1cc(-c2ccc3c(c2)CCO3)n[nH]1 +Cc1nc(CN2CCN(C(=O)N3CCOCC3)CC2)cs1 +CNC(=O)c1ccc(OCc2nc3ccccc3s2)cc1 +CCNC(=O)c1ccc(OC(CC)C(=O)Nc2cc(C)on2)cc1 +CCN(Cc1cc(=O)n(C)c(=O)n1C)c1ccc(F)c(F)c1 +Cc1sc2ccccc2c1S(=O)(=O)N(C)CC1CC1 +COCCNC(=O)C1CCC(C)N(C(=O)Nc2ccc(C)c(C)c2)C1 +Cc1cc2ccccc2n2c(=O)n(CCNC(=O)C(C)C)nc12 +Cc1nc(NC(=O)C2CCN(c3ncccn3)CC2)sc1C +FC(F)(Br)CC(F)(F)Br +CCC(=O)Nc1ccc(N2CCN(C(=O)OC(C)(C)C)CC2)cn1 +Cc1ncc(CN2CCN(CC(=O)N3CCOCC3)CC2)s1 +NC(=O)c1ccc(NC(=O)NCCC2CCCCC2)cc1 +COc1ccc(NC(=O)C2CCN(c3cnn(C)c(=O)c3)CC2)cc1 +O=C1CCCN1CCCNS(=O)(=O)c1cccc(Cl)c1F +O=C(NCCC(=O)N1CCCc2ccccc21)c1cccn2cncc12 +OCc1nc2cc(Cl)ccc2n1Cc1ccccc1 +COc1cccc(CNc2ccc(-n3ccnn3)cc2)c1 +CCn1cc(Br)cc1C(=O)NCC1Cc2ccccc2O1 +CCN(C(=O)CNC(=O)OC)c1cc(C)cc(C)c1 +O=C(Nc1cccc2c1OCCO2)c1cc(C2CC2)on1 +C#CCN1CCN(CCOc2ccc(C#N)cc2)CC1 +CC1(NC(=O)NCC2CN3CCCCC3CO2)CCOC1 +Cc1ncc(-c2cc(=O)[nH]c(N3CCCC(C)C3)n2)c(C)n1 +COC(=O)N1CCN(C(=O)c2oc3c(c2C)C(=O)CC(C)(C)C3)CC1 +COc1ccccc1OS(=O)(=O)c1ccc(F)c(C#N)c1 +CN(C)S(=O)(=O)c1cc(N)c2c(c1)CCCC2 +CNC(=O)c1cccc(NC(=O)NCc2ccoc2)c1 +Cn1cc(C(=O)CSc2nnc(Nc3cccc(F)c3)s2)cn1 +CCCn1nc(C(=O)N(C)C(C)c2ccc(F)c(F)c2)ccc1=O +COc1ccc(CCC2CCCN(C(=O)c3ccc(C)nc3)C2)cc1 +Cc1nn(CC(O)COCc2ccccc2)cc1Br +N#Cc1ccc(CNc2cnn(CC(F)F)c2)o1 +Cc1cc(C)n(-c2ccc(CNC(=O)NCc3cccnc3)cn2)n1 +CCOc1cccc(-c2nc(C3CC3)c(CO)s2)c1 +COc1cc(N)c(-c2nc3ccccc3o2)cc1OC +O=C(OCCn1cncn1)c1ccc(S(=O)(=O)C(F)F)cc1 +COC(C(=O)N(C)CC(=O)Nc1cccc(C)n1)c1ccccc1 +CSc1ccsc1C(=O)Nc1cc(C)cc2cccnc12 +COc1cc(OC)cc(C(=O)Nc2ccc(Cn3cccn3)cc2)c1 +CCC(CO)NC(=O)CN1CCN(c2ccc(F)c(F)c2)C1=O +CCNC(=O)COc1c(F)cc(Br)cc1C(C)=O +Cc1cc2nnc(-c3nccn3C)n2c2ccccc12 +COc1ccc(CNc2cc(F)ccc2F)cc1OC +CC(C)(C)Oc1cc(CNC(=O)NCC2(C)CCCO2)ccn1 +CCC1(CC)Oc2ccc(S(C)(=O)=O)cc2NC1=O +O=C(NCC1CCCO1)c1cncc(-c2csc3ccccc23)c1 +CCc1ccc(CNCCc2cccc(C(=O)NC)c2)cc1 +CC(C)(C)OC(=O)N1CCC(C(=O)Nc2cnn(C(C)(C)C)c2)C1 +COCc1cc(C(=O)NCc2cccc(OCC#N)c2)ccc1F +COc1cccc2c1OCC(NC(=O)NC(C)COCC(C)C)C2 +COCCC1(O)CCN(c2cc(C(F)(F)F)cc(C)n2)CC1C +Cc1nc(CCNC(=O)C(C)NC(=O)C2CCCC2)cs1 +CCc1noc2ncnc(Nc3cc(F)ccc3F)c12 +CCc1nnc(-c2ccc(S(=O)(=O)Nc3cc(C)cc(C)c3)o2)o1 +CCN(C(=O)Cn1c(=O)oc2ccccc21)c1cccc(F)c1 +Cn1nccc1CNc1nnc(-c2ccncc2)o1 +O=C1CC(c2cc(Cl)ccc2F)c2cnn(C3CCCC3)c2N1 +Cc1cnc(C(=O)NC(CCC(C)C)C(C)(C)C)cn1 +Cc1cc(C)c(C#N)c(SC(C)C(=O)N(C)CCC#N)n1 +CCOc1ccc(NC(=O)C2Nc3ccccc3S(=O)(=O)N2)cc1 +O=C(Nc1ccc(Cn2cncn2)cc1)C1CC1c1ccccc1F +O=C(NCc1ccc(F)cc1)Nc1ccc2c(c1)OCO2 +O=C(c1ccccc1Cl)N1CCc2c(nc[nH]c2=O)C1 +CCOC(=O)N1CCCC(C(=O)Nc2nc3c(s2)CCC3)C1 +CC(C)N(Cc1nccn1Cc1cccc(Cl)c1)C(=O)C1CC1 +Cc1ncccc1C(=O)N1CCC(OCC2CCOC2)CC1 +CC(CNC(=O)c1scnc1C1CC1)Oc1ccccc1 +CCCCN(C)C(=O)NC(C)c1nnc2ccccn12 +CN(C)C(=O)c1ccc(CN2CCc3ccccc32)cc1 +C=CCNc1nnc(SCc2ccno2)s1 +CNC(=O)Cc1noc(C2COc3ccc(F)cc3C2)n1 +COCCC1(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)CC1 +Cc1nc[nH]c1-c1nccn1Cc1nnnn1-c1ccccc1 +C#CCNC(=O)C(NC(=O)Nc1ccccc1)C(C)C +CNC(=O)C1CCCCN1c1ccc(N)cc1C#N +C#CCNC(=O)c1ccccc1NC(=O)CCn1c(C)csc1=O +O=C(Nc1nc(-c2ccccc2)cs1)c1ccc(-n2ccnn2)cc1 +CCCNc1nc(-c2ccc(C)n(CCOC)c2=O)cs1 +N#Cc1ccc(-c2noc(-c3cc(F)ccc3Br)n2)nc1 +CN(CCC(F)(F)F)C(=O)c1cn(-c2ccccc2Cl)nn1 +Cc1cc(C(=O)Nc2ccc(CNC(N)=O)cc2)nn1-c1ccccc1 +CCNC(=O)CN(C)C(=O)C(C)Oc1ccccc1 +CNc1nc(-c2ccnc3c2ccn3C)nc2c1CCC2 +O=C(CCc1ccccc1)Nc1ccc(-n2cncn2)cc1 +CN(C)C(=O)CCC(O)c1ccc(Cl)c(N)c1 +CCCCC(=O)N1CCN(CCNC(=O)c2ccsc2)CC1 +CSc1ccc(Cl)c(C(=O)N(C)Cc2nccn2C(F)F)c1 +CCOC(=O)C1CCCN(c2ncnc(NC)c2N)C1 +Cc1ccc(CNC(=O)c2ccc3c(c2)nc2n3CCCC2)cc1 +COc1cc(NC2CCC(O)CC2)nc(SC)n1 +O=C(OCC1CCCO1)c1cc(-c2ccco2)nc2ccccc12 +N#Cc1cccnc1NCC(c1ccccc1)N1CCOCC1 +CCCC1CN(c2nnc(C)s2)CC1NC(=O)C1CCOCC1 +CCOc1ccccc1OCCC(=O)N1CCC(O)CC1 +CCC1CCCN(C(=O)CN(C)c2ncnc3[nH]cnc23)C1 +NC(=O)c1n[nH]c2c1CN(C(=O)c1cc(=O)[nH]c3ccccc13)CC2 +CCC(C)(C)NC(=O)C(C)Oc1ccc(-c2nnco2)cc1 +CC(C)CNC(=O)C(C)S(=O)c1cccs1 +Cc1c(C(=O)Nc2nc3c(s2)CCCC3)cnn1-c1ccccc1 +CS(=O)(=O)c1ccc(OCCNC(=O)c2ccc(F)cc2)cc1 +Cc1noc(C)c1CN(C)C(=O)NCC(C)Oc1cccc(F)c1 +CCOc1ccccc1OC(=O)C1CCN(C(C)=O)CC1 +CCC1CN(C(=O)c2cccnc2)CCC1CC(=O)NC1CC1 +CC(C)OC(=O)CCNC(=O)Nc1ccc(S(N)(=O)=O)cc1 +COc1cc(-c2noc(Cc3cccc(F)c3F)n2)ccn1 +CCOC(=O)c1nc2sc(-c3cccc(C)c3)nn2c1C#N +Cc1ccsc1CN1CC(OCC(=O)N(C)C)C2OCCCC21 +O=C(CN1CCN(c2ccccc2)CC1)NCc1cccc(F)c1 +CS(=O)(=O)c1ccc(C(=O)NCc2ccc(Cl)cc2)cc1 +O=C(Cc1cccc(C(F)(F)F)c1)Nc1ccncc1 +Cc1nn(C)c2c(=O)n(C)c(NC(C)c3ccccc3)nc12 +c1ccc(CCn2nnnc2CN2CCOCC2)cc1 +CC(C)C(NC(=O)c1ccccc1F)C(=O)N=c1sccn1C +COCCN(C)S(=O)(=O)c1c(C)cc(C)cc1C +CCCN(CC1CC1)C(=O)c1cc(=O)c2ccccc2o1 +COc1cc(C)sc1C(=O)NCCCc1cn[nH]c1C +CC(C#N)CN(C)C(=O)c1[nH]c2ccccc2c1Br +Cc1cnc(NC(=O)CNC(=O)OC(C)(C)C)s1 +COC(C)(C)c1noc(CCc2nc(C)no2)n1 +CC(C)NC(=O)c1ccccc1NC(=O)C1CC(=O)N(C)C1 +Cc1cnn(CCC(=O)N=c2[nH]c3ccccc3n2C2CCCC2)c1 +O=S(=O)(C1CC1)N1CCCC2(CC(Nc3ncccn3)CO2)C1 +CC1COCCN1C(=O)Cn1cnc2sccc2c1=O +Cc1ncc(CNC(=O)c2cccc(S(C)(=O)=O)c2)s1 +Cc1nc2c(Nc3ccc(-n4cccn4)cc3)nc(N)nc2n1C +CC(=O)NCC1CCN(C(=O)c2cnc(-c3ccccc3)nc2)CC1 +COCCOc1ccc(C(=O)c2ccccc2F)cc1 +COc1ccc(NC(=O)c2cccc(-c3ccoc3)c2)c(C)n1 +CCn1nc(C(C)C)cc1C(=O)N1CCN(CCO)CC1 +COCCOc1ccc(NC(=O)N(C)C2CCCCCC2)cn1 +CCN1CC(C(=O)N(C)Cc2cccc(C(F)(F)F)c2)CC1=O +CC(=O)N1CCC(CCC(=O)NCc2cccc(NC(C)C)c2)CC1 +NC(=O)c1csc(CNc2cnn(-c3ncccn3)c2)c1 +CC(C)C(C)NC(=O)CNc1cc2c(cc1Cl)NC(=O)CO2 +Nc1nc(-c2ccccn2)nn1C(=O)c1ccc(N2CCNC2=O)cc1 +COc1ccc(-n2c(C)nnc2SCC(=O)OC(C)C)cc1 +Cc1cnn(CC2CCCN2C(=O)Cc2cnn(-c3ccccc3)c2)c1 +CC(C)Oc1ccc(NC(=O)NCc2cccnc2)c(F)c1 +COC(=O)C(NC(=O)Cc1ccc(F)cc1)C(C)O +CC1CCN(C(=O)CNc2cc(S(C)(=O)=O)ccc2F)CC1 +CN1CC(C(=O)Nc2ccccc2Cc2ccccc2)CC1=O +O=C(Cn1cnnn1)Nc1ccc(C(F)(F)F)cc1 +CCCC(=O)Nc1nnc(C=Cc2ccc(OC)cc2)s1 +CNC(=O)c1ccc(NC(=O)Cc2cn3ccsc3n2)cc1 +COCCn1cc(NC(=O)N(CC2CCOC2)C2CC2)cn1 +Cc1nc(-c2ccccc2)nc2c1CCC(=O)N2Cc1ccco1 +COc1c2c(nn3c(C4COCCN4)nnc13)CCC2 +Cc1ccc(Cl)cc1NC(=O)C1CN(C(=O)c2cccs2)C1 +CC(C)Oc1ccccc1CCC(=O)c1ccccn1 +C=CCN1CC2(CCC1=O)CCN(C(=O)C(C)n1cnnn1)CC2 +CC(=O)Nc1cc(NCc2nnc(C(C)(C)C)o2)ccc1F +COC(=O)CCC(=O)Nc1ccc(C(=O)N(C)C2CCCCC2)cc1 +CCOC(=O)CCn1nc(CC)c2c1CCCC2CC#N +Cc1sc2nc(SCC(=O)NCC(C)C)n(C)c(=O)c2c1C +O=C1N(c2cncnc2)CCC12CCCN(c1ncc(F)cn1)C2 +O=C1CCCc2[nH]c(=O)c(C(=O)NCc3cccs3)cc21 +O=C(CN1CCOCC1)c1ccc2ccccc2c1 +COCCNC(=O)CN1C(=O)c2ccccc2Oc2ncccc21 +CC1CC1C(=O)NCc1cccnc1-n1cccn1 +N#Cc1cccnc1OCCCOc1ccccc1 +O=C(CNC(=O)Nc1cnn(-c2ccccc2)c1)Nc1cccnc1 +CC(Sc1ccccc1)C(=O)OCc1cccc(C(N)=O)c1 +Cc1ccc(-c2nc(-c3ccncc3)nn2C)s1 +Cc1noc(CCCC(=O)Nc2cc3c(cc2Cl)OCCO3)n1 +COc1ccc(SCCC(=O)Nc2c(C)n[nH]c2C)cc1OC +Cc1cnc(CCNC(=O)c2ccn(-c3ccccc3)n2)s1 +Cc1nccn1Cc1cccc(CNC(=O)NCCc2ccccn2)c1 +Cc1csc(NC(=O)C2CC(=O)N(C3CCOCC3)C2)n1 +CNc1cncc(C2CCN(S(=O)(=O)c3cn(C)cn3)CC2)n1 +Cc1csc(N2CCN(c3cncc4nnnn34)CC2)n1 +O=C(NCCC(=O)N1CCCC1)c1cc2ccccc2oc1=O +CCOCCC1CCN(C(=O)Cc2ccc(F)cc2F)CC1 +Cc1ccc(O)c(NC(=O)CNC(=O)c2cc(F)cc(F)c2)c1 +Cc1cc(C(=O)Nc2nn(-c3ccccc3Cl)cc2C)ncn1 +Cc1noc(-c2ccccc2OCC(=O)N(C)C)n1 +CC(C)N(C(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1)C(C)C +CCn1nc(C)cc1C(=O)N1CCc2cc(OC)c(OC)cc2C1 +Cc1ncsc1CNS(=O)(=O)c1ccc(Cl)c(N)c1 +CCCNC(=O)CNC(=O)NC(C)c1ccc(C)c(F)c1 +CN(Cc1ccccn1)C(=O)NCc1cnn(Cc2ccccc2)c1 +CC(C)N(C(=O)c1ccnc(OCC(F)F)c1)C(C)C +CC(C)c1cc(C(=O)NCCN2CCNC2=O)nc2ncnn12 +CC(C)NC(=O)CCn1cnc2ccc(Br)cc2c1=O +O=C(c1ccc(-c2ccccc2F)o1)N1CCOCC1C1CC1 +CC(C)Cc1ccc(CCCn2cc(N)cn2)cc1 +Cc1cc(C)c2nc(NC(=O)c3cnc(C)cn3)sc2c1 +Cc1nc(CCC(=O)c2cccc(Cl)c2)sc1C +Cc1ccc(Cl)cc1NC(=O)NCCCCn1ccccc1=O +C=CCNC(=O)c1cc(-c2ccccn2)nc2ccc(C)cc12 +Cc1cc(C)c(C(=O)N(C)Cc2c(C)noc2C)c(C)c1 +CCC(c1cccnc1)N(C)C(=O)c1cn2ccsc2n1 +O=C1CC(c2ccccc2)N(Cc2cccc(-n3cccn3)c2)CCN1 +COC(=O)CNC(=O)c1cc(-c2ccncc2)nc2ccccc12 +Cc1cc(Cl)ccc1OC(=O)C1CCN(c2cnccn2)CC1 +CCc1ccc(CNc2ccc3[nH]ncc3c2)nc1 +Cc1csc(C(C#N)C(=O)CC(C)CCc2ccccc2)n1 +O=C1CSc2ccc(NC(=O)NCc3ccncc3)cc2N1 +Cc1ccc(-n2cnc(C(=O)Nc3ccc(F)c(F)c3)n2)cc1 +O=C(CCc1nc2ccccc2o1)N1CCCCC1 +CSc1ccccc1NC(=O)C(C)OCC1CCCO1 +Cn1cc(CNCc2ccc(-n3ccnc3)nc2)c(-c2cccnc2)n1 +Cc1cccc(C2(NC(=O)NCc3ncn(C)n3)CCCC2)c1 +O=C(COc1ccc(-c2nnco2)cc1)NCC1(c2ccccc2)CC1 +CN(C)C(=O)COc1ccc(C(=O)c2ccccc2)cc1 +Cc1nn(C)c2ncc(NC(=O)Cc3ccc(F)c(F)c3)cc12 +CC(Oc1cccc(N)c1)C(=O)Nc1ccccc1C(C)C +N#Cc1ccccc1Cn1nc(-c2nccc3ccccc23)oc1=O +COC(=O)CCNC(=O)c1cn(C)nc1-c1ccc(F)cc1F +CCc1nnc(NC(=O)CSc2ccccc2C)s1 +O=C(Nc1ccc(OCc2nc(-c3ccncc3)no2)cc1)C1CC1 +CC(C)CN(CC(C)C)C(=O)C1CCN(C(=O)N2CCCC2)CC1 +CCOC(=O)C1=C(CNc2c(C)cc(C)cc2Cl)NC(=O)NC1 +CCCCCn1nc(C(=O)NC(C)(C)C#N)c2ccccc2c1=O +Cn1nc(C(C)(C)C)cc1C(=O)NC1C2CCOC2C1(C)C +COCCN1C(=O)c2cc(Br)ccc2S1(=O)=O +CCOCC1CCCN(C(=O)c2ccc(C(=O)N(C)C)nc2C)C1 +CN(Cc1ncnn1C)C(=O)c1c(F)cc(Br)cc1F +Cc1ccc(Cl)cc1OCC(=O)NC1CCOCC1 +C=CCN(C)S(=O)(=O)c1ccc(NC(=O)c2cnccn2)cc1 +CCc1ccsc1C(=O)Oc1cccc(C(=O)N(C)C)c1 +Cc1oc(N)c(C#N)c1-c1ccc2c(c1)C(C)(C)C(=O)N2 +Nc1cc(N)nc(SCC(=O)OCn2nnc3ccccc32)n1 +Cc1ccccc1NS(=O)(=O)c1ccc2c(c1)oc(=O)n2C +COc1cc(NC(=O)c2ccc(C#N)cc2)ccc1N1CCCC1=O +Cc1ccc(Oc2ccccc2)c(NCc2nnc(C3CCC3)o2)c1 +N#Cc1ccc(COC(=O)c2ccc3c(c2)OCCO3)cc1 +CC(C)(C)NC(=O)Nc1cccc(Cn2nc3ccccn3c2=O)c1 +Cc1cc(NC(=O)CNc2ccccc2C(=O)NC(C)C)n(C)n1 +COc1ccc(-c2ccc(C(=O)N3CCOCC3)c(F)c2)cc1 +Cc1cc(C)c2c(CC(=O)Nc3ccncc3)coc2c1 +COc1ccc(C(=O)N(C)C(C)(C(N)=O)C(C)C)cc1 +CCn1ncc(-c2ccnc3c(C#N)cnn23)c1C +CCC(CC)CN1CC2(CCN(C(=O)C(CC)OC)CC2)OC1=O +COCCNS(=O)(=O)c1cc(Br)cnc1N +Cc1cc(C)c(S(=O)(=O)NC2CCC(O)CC2)c(C)c1 +CC(O)CC(C)CNC(=O)Cc1csc(C(C)(C)C)n1 +Cc1ccc(CCCCC(=O)NCc2nnc3n2CCCCC3)cc1 +CC1CN(Cc2cccc(NCc3ccc(CO)o3)c2)CC(C)O1 +CCCc1nc(N2CCC(O)(c3ccccc3)C2)c2cnn(C)c2n1 +CCOc1ccc(OCC#N)c(Br)c1 +CCc1cc(C(=O)NCCOc2cccc(Cl)c2)[nH]n1 +CN(CCOc1cccc(F)c1)C(=O)c1cnc2c(c1)ncn2C +O=C(c1cccc(-c2ccoc2)c1)N1CCC2OCCCC2C1 +Cc1ccc(C(=O)N(C)CC(C)C)cc1NC(=O)c1ccccc1 +CNC(=O)Oc1ccc(C(=O)c2ccccc2)cc1 +COC(=O)c1ccc(CN(C)S(=O)(=O)N(C)C)cc1 +CN(C(=O)c1cccc(-n2cccc2)c1)c1nccs1 +CCOc1cc(F)ccc1NC(=O)COc1ccccc1OC +COc1cc2nc(CC#N)n(CC#N)c2cc1OC +CCn1nc(C(=O)Nc2nc3c(SC)cccc3s2)cc1C +CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1cc(N)ccc1O2 +COc1ccc(OC)c(NC(=O)CCS(=O)(=O)c2ccccc2)c1 +O=C(CCNS(=O)(=O)c1ccc(F)cc1)NC1CC1 +Cc1ccoc1C(=O)NCC(c1cccs1)N1CCOCC1 +CCC(C)(C)c1ccc(OCC(=O)N2CCNCC2)cc1 +CC1(C)C(=O)Nc2ccc(-c3cc(Cl)c(C#N)cn3)cc21 +CCc1ccc(C2COCCN2Cc2c[nH]c(C(=O)OC)c2)o1 +CCC(C)C(=O)C(C#N)c1ccc(F)cc1Cl +CCNc1ccc(S(=O)(=O)N(C)C(C)COC)cn1 +O=S(=O)(NC1CC2CCC1C2)c1ccc2c(c1)OCCO2 +O=C(CCc1nc(Cc2ccccc2)no1)NCC1CCCO1 +CN(CCO)C(=O)Nc1ccc(-c2nccn2C(F)F)cc1 +COC(=O)c1c(NC(=O)CCc2ccco2)sc2c1CCCC2 +CCc1onc(C)c1NC(=O)C1CC1c1ccccc1F +CC(=O)N1CCC(C(=O)NC2CCC3(CC2)OCCO3)CC1 +COc1ccc(-c2nc(CNC(=O)c3cccc(C#N)c3)n[nH]2)cc1 +CN(C(=O)c1ccco1)C(C#N)c1ccc(F)cc1 +COc1cc(NC(=O)c2cccc(C)c2)ccc1NS(C)(=O)=O +Cc1nc(C)n(CCNc2nc(C3CCCC3)nc3c2cnn3C)n1 +CC(C)c1ccc(OCC(=O)Nc2ccccc2-n2cnnn2)cc1 +CC1CC1C(=O)N1CCCC(c2n[nH]c3nccnc23)C1 +Cc1ccc(C(=O)NCC(=O)N(C)C(C)c2cccs2)s1 +CCNC(=O)C(C)NC(=O)c1sc2nc3n(c(=O)c2c1C)CCC3 +O=C(Cc1ccc(F)cc1)N1CC2CC(C1)c1cccc(=O)n1C2 +NC(=O)c1csc(N2CCN(CC=Cc3ccccc3)CC2)n1 +Cc1cc(C)n(-c2ccc(C(C)NC(=O)c3nccnc3N)cc2)n1 +Cc1cccc(OCc2nc(-c3cccc(N)c3)cs2)c1 +CCCNC(=O)CNC(=O)N(C)Cc1ccc(C(F)(F)F)cc1 +C=CCCCN(C)C(=O)c1c[nH]c2cc(OC)ccc2c1=O +CCOC(=O)c1cccc(NC(=O)c2cccc(OC(C)=O)c2)c1 +COC(=O)c1ccc(Nc2nc(C)cc(C)n2)cc1 +CNC(=O)NCC(=O)N(CCc1ccccc1)C1CCOC1 +O=C(Cc1ccccc1F)N1CCN(Cc2ccccn2)CC1 +COC(=O)c1sc2nc(-c3cccc(F)c3)[nH]c(=O)c2c1C +COc1ccc(OCc2noc(CNC(=O)c3cc(C)on3)n2)cc1 +CC(C)(C)C(=O)N1CCC(C(=O)NCc2ccccn2)CC1 +Cc1csc(NC(=O)c2csc(NCc3ccco3)n2)n1 +CN(Cc1c(F)cccc1Cl)C(=O)c1cccs1 +Cc1nc(CNc2ccc(-c3cnco3)cc2)cs1 +COc1cccc(S(=O)CC2CCN(C(=O)OC(C)(C)C)C2)c1 +COc1ccc(NC(=O)c2cnns2)cc1N1CCCC1=O +O=C(Cc1ccccc1)NCCC(=O)N1CCOc2cc(F)ccc21 +CC(C)C(NC(=O)c1cnn2c1OCCC2)C(=O)N1CCCCC1 +CCC(CO)NC(=O)Nc1cccc(C(=O)NC)c1C +CCOC(=O)N1CCc2nc3cc4c(cc3c(C)c2C1)OCO4 +C=CCn1c(SCC(=O)NCCC#N)nc2ccccc21 +CCCNC(=O)N(CC)S(=O)(=O)c1ccc(Cl)cc1 +Cc1n[nH]c(C(=O)NC(C)(C)c2ccccc2)c1Br +Cc1cc(F)ccc1NC(=O)CCNC(=O)C1CC1C +Cc1nc(NCc2ccco2)cc(-c2cccc(C(F)(F)F)c2)n1 +C=CCC(=O)N1CCCC(C(=O)c2cc(C)c(OC)c(C)c2)C1 +Cc1ccc(NC(=O)C(C)Oc2ccccc2C#N)c(O)c1 +CCN(CC(=O)NC(C)C)C(=O)CC1OC(=O)c2ccccc21 +CCCc1nc2c3cnn(-c4ccc(C)c(Cl)c4)c3ncn2n1 +Nc1cc(Cl)ccc1C(=O)NCCN1CCOCC1 +CC(Sc1nncn1C)C(=O)NCc1ccoc1 +CCc1nc2n(n1)CCCC2NC(=O)C1CC1c1ccccc1Cl +O=C(c1ccc(-n2cnnn2)cc1)N1CCc2ccccc21 +CC1CCN(C(=O)c2ccc(Br)c(F)c2)C1 +CC(C)(C)OC(=O)CN1CCN(C(=O)OC(C)(C)C)CC1 +O=C(NC1CC1)C1CCCN1c1ncnc2sccc12 +CN(C)S(=O)(=O)c1ccc(CCc2ccccc2)cc1 +CC(C)OCCC(=O)Nc1ncn(CC(=O)N2CCCCCC2)n1 +CN(C(=O)c1cc(-c2ccccc2Cl)[nH]n1)C1CC1 +COc1cccc(CNc2cc(C(=O)N3CCOCC3)ccc2C)c1 +O=C(CSc1ccccn1)NCc1cccs1 +CC(C)OCCCNC(=O)C1CCN(C(=O)c2cnccn2)CC1 +CN(C)S(=O)(=O)Nc1ccc(-n2ncc3ccccc32)cc1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2nc3c(C)cccc3s2)c1C +c1ccc(CCSc2nnnn2Cc2ccco2)nc1 +Cc1cc(COC(=O)c2occc2-c2ccccc2)on1 +Cc1[nH]nc(NC(=O)C2CCOCC2)c1-c1cccc(Cl)c1 +Cc1cccc(C)c1C(=O)NCC1CCC(C(=O)N(C)C)O1 +CCc1cc(NCC(C)S(N)(=O)=O)n2ncnc2n1 +O=C(CS(=O)(=O)c1ccccc1F)Nc1cc(Cl)ccc1F +CC(=O)C(NC(=O)CSc1ccc(F)c(F)c1)C(C)C +CCOc1ccc(CCC(O)c2cccs2)cc1OC +COCCCOc1ccccc1NC(=O)NC(C)C +COc1ccc(-n2cc(C(=O)N3CCCC3)c3ccccc3c2=O)cc1 +CCSc1ccc(S(=O)(=O)NCCO)cc1 +CSc1ccccc1C(=O)c1ccccc1CN1CCOCC1 +O=C(c1ccccc1)N1CCN(c2cc(-n3cccn3)ncn2)CC1 +CC(C)COc1cccc(CNC(=O)c2cc[nH]n2)c1 +CCOc1ccc(NC(=O)c2cc3c(cc2Cl)OCCO3)cc1 +COc1cccc(SCC(=O)NCC(F)(F)F)c1 +CC(C)c1ccc(C(C)(O)CNCc2cccnc2)cc1 +O=C(Nc1ccc2c(c1)COC2)c1cccc(OC(F)F)c1 +Cc1nc2ccc(NCc3cnn(C)c3)cc2s1 +CCc1ccc2c(c1)C(O)(CC(=O)c1ccco1)C(=O)N2 +CCc1ccc(NC(=O)C(O)c2ccc(OC)cc2)cc1 +CCC(C)C(=O)Nc1cccc(CNC(=O)NCc2cccnc2)c1 +CCC(=O)N1CCCc2ccc(NC(=O)c3cccc(C)c3)cc21 +O=C1CCN(Cc2cc(C(F)(F)F)ccc2Cl)CCN1 +COc1cccc(CC(=O)N2CCCC2CN2CC(C)OC(C)C2)c1 +Cc1c(Cl)c(C)c2c(c1Br)OCC(=O)N2C +CC(=O)C(C)N1CCNc2cc(Cl)c(Cl)cc21 +Cn1nccc1C(=O)N1CCC(Oc2cccc(Cl)c2)C1 +O=C(Cc1ccccc1Br)NCc1ccncc1 +Cc1nnc(SCc2noc(C3CC3)n2)c(C#N)c1C +COC(=O)C=C(C)c1cncc(-c2cccs2)c1 +CCOCCNC(=O)N1CCc2ccc(Cl)cc2C1 +Cc1n[nH]c(C)c1NC(=O)CN1CCCc2ccccc21 +Nc1[nH]nc(-c2cccc(Cl)c2)c1Br +CCCOc1cccc(-c2ccc(CO)c(=O)[nH]2)c1 +O=C(c1cccc(-n2cccc2)c1)N1CCN(C(=O)C2CC2)CC1 +Cc1nc(CNc2cc(F)ccc2OC(C)C)no1 +O=C(NCCc1ccccn1)c1ccc(N2CCCOC2=O)cc1 +O=C(COC(c1ccccc1)c1ccccc1)Nc1ccccn1 +OCc1nc2ccc(-c3ccc(F)cc3Cl)cc2[nH]1 +Cc1cnc(C(=O)NCCc2ccccc2)c2cccc(N)c12 +Cc1cccc(C(=O)NCCC(=O)N2CC=C(c3ccccc3)CC2)c1 +CC(C)CNC(=O)N1CCCC(CC(=O)N(C)c2ccccc2)C1 +CC(C)c1cc(C(=O)N2CCOCC2C2CC2)nn1-c1ccccc1 +CCc1c(CO)nnn1CCCOc1cccc(C)c1 +COc1cccc(-c2nc(C)c(CC#N)s2)c1OC +CCOc1cc(N)ccc1NC(=O)c1cccc(C)c1 +CCn1nc(NC(=O)c2cnc3ccccn3c2=O)cc1C +CN(C(=O)c1ccncc1)C1CCc2ccccc21 +Cc1ccc(C)c(N(c2ccccc2N)S(C)(=O)=O)c1 +Cc1ccc(CNc2ccccc2Cn2cncn2)o1 +O=C(c1ccccc1)C1CCN(C(=O)c2cccc3ncccc23)CC1 +CCOc1ccc(NC(=O)c2cccnc2N2CCCCC2)cc1F +O=C(NCC(=O)N(Cc1cccc(F)c1)C1CC1)C1CCCC1 +Fc1ccc(CNc2cnn(-c3ccccc3F)c2)cc1 +O=C(c1ccncc1)N1CCCn2nnc(COCCO)c2C1 +Cc1ccccc1CNC(=O)C(C)Oc1ccccc1C(N)=O +CCCC(C)CNc1ccc(Cl)cc1C(N)=O +CCOc1ccc(N)cc1C(=O)NC1CCCC(C)C1 +NC(=O)c1ccccc1NCC(=O)N1CCOCC1 +CNC(=O)c1cccc(NC(=O)NC2Cc3ccccc3C2)n1 +CCCn1nc(C)c(CNc2cccc(C(=O)NC)n2)c1C +CCn1cc(NC(=O)NCCNC(=O)C2CC2)cn1 +COC1CCN(C(=O)c2ccn(C)n2)CC1Cc1cccc(C)c1 +Cc1nc2ccccc2nc1CN1CCOC2CCCCC21 +Cc1nc(CNC(=O)c2c[nH]nc2-c2cccc(Cl)c2)no1 +COC(=O)c1cc(CSc2nc(C)c(C)c(C)c2C#N)oc1C +CCCc1nnc(NC(=O)CCc2ccc(C)cc2)s1 +Cc1nn(C)c(C)c1C(C)C(=O)NC(C)c1ccc2c(c1)OCCO2 +CCc1nc(-c2cccnc2)cc(N2CCC(=O)CC2)n1 +Cc1ccnn1-c1ccc(C(=O)NCC2CN(C3CC3)CCO2)cc1 +CCc1nnc(NC(=O)CN(C)C(=O)c2ccsc2)s1 +CCc1c(C(=O)N(C)CCN2CCCC2=O)cnn1-c1ccccn1 +CCOc1cccc(COC(=O)c2oc(C)nc2C)n1 +Cc1cnc(NC(=O)Cn2nnc3ccccc32)s1 +CC1CCCC(NC(=O)Cn2ccc(N)n2)C1C +Cc1cccc(C)c1NC(=O)c1cc(C)n(C2CC2)c1C +O=C(Nc1ccncc1)c1cccnc1Oc1ccccc1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3c(F)cc(F)cc3F)c2)n1 +CCC(=O)Nc1cccc(C(=O)NCc2ncc[nH]2)c1 +CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2Cl)c1 +CCCCSc1nnc2[nH]c(=O)c3c(n12)CCCC3 +CC(C)CC(NC(N)=O)C(=O)Nc1cccc(-c2nncn2C)c1 +C#CCOc1ccccc1CNCCc1nc2cc(F)ccc2n1C +O=C(CNC(=O)c1cccs1)Nc1ccccn1 +CC(C)c1c(C(=O)NCC2CCCO2)nnn1-c1ccccc1 +CC(C)(CNC(=O)Nc1ccc(Br)cc1Cl)C(N)=O +CC(NC(=O)c1cc(F)cc2[nH]cnc12)c1cccc(OC(F)F)c1 +O=C1C(NC(=O)N2CCCC2CO)CCN1c1c(F)cccc1F +O=C1CC(C(=O)Nc2nc(-c3ccco3)cs2)c2ccccc21 +NS(=O)(=O)c1ccc(C(=O)NC2CCC(O)CC2)cc1 +Cc1n[nH]cc1NC(=O)C1CCCCN1C(=O)C(C)C +COc1cc(NC(=O)Cc2ccsc2)c(C(=O)N(C)C)cc1OC +O=C(NCC(=O)N1CCc2ncccc2C1)c1ccc(Cl)cc1 +CCN(C)c1ccccc1NC(=O)N1CCC(O)(C(F)(F)F)CC1 +CCOC(=O)CN(C)C(=O)c1ccc(OC)nc1 +COc1ccc(CNC(=O)c2ccc(N)cc2)c(Cl)c1O +CN(C(=O)c1ccnc(SC(C)(C)C)c1)C1CCOC1 +COC(=O)c1cc(NC(=O)COC(=O)c2cccnc2)ccc1Cl +Cc1ccc(NC(=O)NCc2nn(C)c(=O)c3ccccc23)cc1C +CC(=O)Nc1cccc(NC(=O)c2cccc(-n3cnnn3)c2)c1 +CCCCOC(C)C(=O)NC1CCN(c2ccccc2)C1=O +CN(c1ncnc2c1cnn2-c1ccccc1)C1CCCCC1 +Cc1ccsc1CN(C)C(=O)c1cnc2onc(C)c2c1 +CCCn1c(C)nnc1SC(C)c1nc(-c2ccccc2)no1 +Cc1ccc(C(=O)Nc2cccc(NC(=O)NC(C)C)c2)n1C +CCOc1cc(Cl)c(S(=O)(=O)n2ccnc2)cc1Cl +Cc1cccc2c1C(NC(=O)c1cccs1)CNC2 +Cc1cc(C)n(C2CCN(C(=O)c3ccn(C)n3)CC2)n1 +CCNC(=O)c1cccc(-c2ccnc3c2ccn3C)c1 +NC(=O)c1ccsc1NC(=O)c1cccc(F)c1 +CC(=O)Nc1ccc(NC(=O)c2ccc(-n3ccc(C)n3)cc2)cc1 +Cc1occc1C(=O)NCC(=O)Nc1ccc(F)c(C(F)(F)F)c1 +Cc1cc(C(=O)N(C)CC2CCCO2)nn1-c1ccccc1 +O=c1cc(N2CCC(n3c(=O)[nH]c4ccccc43)CC2)[nH]c(=O)[nH]1 +CCc1nc(C(C)NC(=O)c2ccc3ccccc3n2)cs1 +CC(C)(C)C(=O)NCCC(=O)Nc1nc2ccccc2s1 +CCCCNC(=O)Nc1ccc2c(c1)NC(=O)C(C)(C)O2 +CC1Cc2cc(C(O)CN3CCN(c4ccccc4)CC3)ccc2O1 +NC(=O)C1(Oc2ccc(Br)cc2)CCCC1 +c1ccc(-c2noc(CN3CCN(c4nccs4)CC3)n2)nc1 +CCc1ccc(NC(=O)C2CCCN2C(=O)Cc2cccs2)cc1 +CC(C)CCC(=O)Nc1ccc(CN2CCCC2=O)cc1 +O=C(c1ccc(Cn2cccn2)o1)N1CCOCC1 +CC(CN1CCOCC1)OC(=O)c1cn(C)nc1C(C)(C)C +Cc1cc(CNC(=O)c2sc(Cc3ccc(F)cc3)nc2C)on1 +CCC(=O)N1CCCCC1C(=O)Nc1nc2ccc(OC)cc2s1 +Cc1ccsc1CNS(=O)(=O)c1cccc(Cl)c1 +O=C(Cc1cccc(Cl)c1)N1CCn2nncc2C1 +COc1c(Cl)cccc1NC(=O)N(C)CC1CCCCO1 +COc1ccc(C(O)CNc2cccc(F)c2)cc1F +COC(=O)c1ccc(C(=O)Nc2ccccc2Br)cn1 +Cc1nccc(CNS(=O)(=O)c2c(C)n[nH]c2C)n1 +Cn1cnc2cc(-c3noc(COc4ccccc4)n3)ccc21 +CCCCCNC(=O)Cc1noc2c(N)cc(CC)cc12 +CCc1cccc(N2CCC(NC(=O)c3cccnc3)CC2)c1 +CCNC(=O)CN(CC)C(=O)c1cc(C)n(C(C)C)c1C +Cn1c(=O)n(Cc2ccc3c(c2)OCO3)c(=O)c2ncccc21 +COC(=O)c1ccc(NC(=O)NC(C)(C)CO)cc1 +O=C(NC1CC(O)C(CO)C1)c1ccc(OC(F)(F)F)cc1 +COc1cc(CNC(=O)c2cc(C)sc2C)ccc1C +O=C(CC1CCCC1)NCc1cn2ccsc2n1 +Brc1ccccc1C1CN(Cc2cc[nH]n2)CCO1 +COc1ccc2c(C)cc3nnc(SCC(=O)N(C)C)n3c2c1 +CCN1CCN(C(=O)Cc2cc(C)ccc2C)CC1 +Cc1noc(C)c1CN(C)c1nccc(C(F)(F)F)n1 +Cc1cccc(C)c1NC(=O)CNC(=O)c1oc2ccccc2c1C +Cc1ccc(NCc2ccsc2)cc1S(C)(=O)=O +COC(=O)CCC(=O)Nc1cccc(C(=O)N2CCC(C)CC2)c1 +O=C(COc1ccc2c(c1)CCC2)N1CCCC1c1ccccn1 +COc1cc(-c2noc(CSc3ccc(F)cc3)n2)ccn1 +COC(=O)C1=C(C)C(C(=O)N2CCC(C(N)=O)CC2)=NC1C +COc1cccc(OC)c1C(=O)Nc1ccc2c(c1)CCC(=O)N2C +Cc1ccoc1C(=O)N1CCc2[nH]nc(-c3ccc(Cl)cc3)c2C1 +CCN(CCn1cccn1)C(=O)Nc1c(F)cccc1C(F)(F)F +CNC(=O)c1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cc1 +COC(=O)C(C)Sc1nnc(-c2c[nH]c3ccccc23)o1 +COc1cc(C(=O)N2CCCCC2)cc(N)c1OC +CC(C)c1nnc(SC2CCOC2=O)n1C1CC1 +Cc1ccccc1NCc1nc2ccccc2c(=O)[nH]1 +CCOc1ccc(-n2c(=O)c3ccccc3n3c(CC)nnc23)cc1 +N#CCn1ccnc1-c1ccccc1Br +Brc1ccccc1CN1CCOCC1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1cc(F)ccc1F +O=C1CN(C(=O)CCc2c[nH]c3ccccc23)CCN1 +O=C(NCC1CCCO1)c1noc2c1CSc1ccccc1-2 +O=C(CSc1nnc(C2CC2)n1C1CC1)c1ccccc1Cl +O=C1c2ccccc2NC(c2ccc(F)cc2F)N1c1ccncc1 +CCS(=O)(=O)N1CCCC(C(=O)NC2CCCCC2C)C1 +CC1CC1C(=O)NCCC(=O)N1CCC(C)C2CCCCC21 +O=c1[nH]cc(-c2cccc(S(=O)(=O)N3CCCC3)c2)c(=O)[nH]1 +CN(C)C(=O)N1CC2COCC2(CN2CCOCC2)C1 +Cc1cc2oc(C(=O)NCc3cnn(C)c3)c(C)c2cc1Cl +Cc1ccc2c(c1)C(=O)CC(c1ccc3c(c1)OCCO3)O2 +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)OCC1CCCO1 +COC(=O)Nc1ccc(CNS(=O)(=O)c2ccc(C)cc2C)cc1 +Cc1ccc(-c2noc(-c3ccccc3C(N)=O)n2)nn1 +CCCCS(=O)(=O)NCCc1c[nH]c2ccccc12 +COCC1CCCN(C(=O)NCc2ccc(-c3cccnc3)cc2)C1 +Cc1ccccc1CN1C(=O)CCC1(C)C(=O)NCc1ccccc1 +COc1ccc(OC)c2sc(NC(=O)c3ccnn3C)nc12 +CCn1c(C)nnc1SCc1ccc2ccccc2n1 +COC(=O)C(C)(C)NC(=O)c1cnn(CC(C)C)c1C(F)F +CCc1ccccc1NC(=O)CCS(=O)(=O)N1CCNCC1 +O=S(=O)(c1cccc2cnccc12)N1CCC(O)C1 +COc1cccc(C(=O)N(C)CC(C)C#N)c1OC +CNC(=O)c1cc(Cl)ccc1NC(=O)c1cc(SC)ccc1C +CC(C)(C)c1nnc(SCCC(=O)Nc2ccc(F)cc2)n1N +COC(=O)CSc1nnc(-c2ccc(O)cc2)n1Cc1ccco1 +O=C(NCc1cccnc1)c1ccc(C(=O)NCc2cccnc2)cc1 +Cn1ccc(C(=O)N(Cc2ccco2)CC2CCCO2)cc1=O +COC(=O)c1ccc(Oc2ccc3nnc(C)n3n2)cc1 +CNC(=O)c1cccc(CNC(=O)CCc2c(C)[nH]c(=O)[nH]c2=O)c1 +CCn1cc(NC(=O)N(C)CCCOC)ccc1=O +Cn1c(=O)c2c(NC(=O)c3ccccc3Cl)ccnc2n(C)c1=O +O=C1NC2(CCN(Cc3cccnc3)CC2)Oc2ccccc21 +COC(=O)c1ccc(NC(=O)NCC(=O)Nc2cccnc2)c(C)c1 +Cc1c(Cl)c(-c2nnc(-c3ccc(OC(F)F)cc3)o2)nn1C +NC(=O)C1CCN(C(=O)c2cccc(Br)c2)C1 +COc1cccc(OC)c1COc1c(C#N)cccc1OC +COC(=O)c1cc2c(=O)n(-c3cccc(Cl)c3)ccc2nc1C +Cc1ccn2c(=O)c(C(=O)Nc3cc(Cl)ccc3C)cnc2c1 +CN(C)S(=O)(=O)c1ccc(C(=O)Nc2ccc(F)cc2F)cc1 +Cc1nc(CNC(=O)NCC(O)COc2ccc(F)cc2)oc1C +CC1CN(C(=O)CNC(=O)CC23CC4CC(CC(C4)C2)C3)CC(C)O1 +COc1cccc(CC(C)NC(=O)NCc2sc(C)nc2C)c1 +CCC(C)(CO)NC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CC(Cc1nc(-c2ccncc2)no1)S(=O)(=O)c1ccc(F)cc1 +Cc1nc(CCC(=O)N(c2cccnc2)C(C)C)oc1-c1ccccc1 +Cc1cc(=O)c(O)c(CN2CCOCC2)n1CCC(C)C +COC(=O)CN1C(=O)C(C)(C)c2cc(NC(=O)C(C)C)ccc21 +CCCN(CC(=O)Nc1ccon1)C(=O)C(C)C +COc1csc(C(=O)N2CCOCC2c2c(C)n[nH]c2C)c1 +O=C(c1ccco1)N1CCC(Nc2cccnc2)C1 +Cc1noc(CNC(=O)Cc2ccc(F)c(F)c2)n1 +CC1CN(C(=O)Nc2ccc(F)cc2F)CC(C)O1 +Cc1cc(NC(=O)c2ccc3[nH]c(=O)[nH]c3c2)n(C)n1 +O=C(Cc1csc(NC(=O)C2CCCC2)n1)Nc1cccnc1 +CCCC1CN(C(=O)c2coc(-c3ccccc3)n2)CCO1 +CC(c1cc2ccccc2o1)N(C)S(=O)(=O)C(C)C +COC(C)(C)c1noc(C2Oc3ccccc3C2C)n1 +CCC(=O)N1CCCN(C(=O)Nc2ccc(F)cc2C)CC1 +Cc1ccc(S(=O)(=O)NCCCNS(C)(=O)=O)cc1F +CNC(=O)c1ccc(NC(=O)c2cccc(NC(C)=O)c2)cc1 +Cc1ncc(CNC(=O)NCc2nc(-c3ccccc3)cs2)s1 +O=S(=O)(Nc1ccc(F)cc1F)c1ccc(F)cc1F +Cc1cccn2cc(C(=O)N3CC(C(N)=O)C3)nc12 +COc1ccc2c(c1)CCCC2CC(=O)Nc1nccn(C)c1=O +O=C(Nc1ccc2nccnc2c1)c1ncn(-c2ccccc2)n1 +Cn1cccc1-c1cc(C(=O)NCc2nnc3n2CCCCC3)[nH]n1 +CC(C)(CNc1nncc(-c2ccccc2)n1)N1CCOCC1 +COCc1nc(CNC(=O)c2nc3ccccc3[nH]2)no1 +O=C1CC(c2cc(F)ccc2F)c2cc3c(cc2N1)OCCO3 +COCCn1c(N2CCCC2)nc2c1c(=O)[nH]c(=O)n2C +O=C(NCCc1cccc(O)c1)c1ccc(-n2cccn2)cc1 +Cc1ccoc1-c1nnc(CSc2nnnn2CC(C)C)o1 +O=S(=O)(NCCN1CCOCC1)c1ccc(Cl)c(Cl)c1 +Cc1ocnc1CNC(=O)Nc1ccc(F)cc1OCC1CC1 +CSc1ccc(CCNC(=O)c2noc3c2CCCC3)cc1 +CC(=O)c1ccccc1NC(=O)C1CC(=O)N(Cc2ccccn2)C1 +COC(=O)CSc1ncnc2cc(OC)c(OC)cc12 +O=C(OCCCc1ccccc1)c1ccc(=O)n(-c2ccccc2)n1 +CCc1c(C(=O)N2CC(C)OC(C)C2)nnn1-c1cccc(Cl)c1 +CCNC(=O)NCCNC(=O)c1ccc(F)cc1 +Cc1ccc(-n2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)nn2)cc1 +COC(=O)c1ccc(OCC(=O)c2ccc3c(c2)CCO3)c(OC)c1 +COc1ncc(NCc2cnc(C(C)C)s2)cc1C(N)=O +c1ccc(C(c2ccccc2)c2nc(-c3cccnn3)no2)cc1 +CCC(C)N(Cc1cccnc1)C(=O)CCc1c(C)nc(=O)[nH]c1C +Cc1cccnc1-n1nc(C2CC2)nc1-c1ccc2oc(=O)n(C)c2c1 +COc1cccc(-c2nnn(Cc3ccccc3)n2)c1 +Cc1nnc(CN(C)C(=O)c2cc(F)ccc2O)n1C +NC(=O)Cc1ccc(-c2nc3ccccc3s2)cc1 +COc1ccc(-c2cc(-c3ccccc3)nc(N)n2)cc1OC +Cn1ncc(C(=O)N=c2[nH]c3ccccc3s2)c1-n1cccc1 +CN(CC1CCCO1)C(=O)CCCc1cc(F)ccc1F +COc1ccc(CNC(=O)OC(C)(C)C)nc1OC +Cc1ccc(S(C)(=O)=O)cc1C(=O)N1CCCC(C)C1 +Fc1ccc(-c2ccnc3nc(-c4ccc5c(c4)OCCO5)nn23)cc1 +OCc1cccc(Oc2ncccc2C(F)(F)F)c1 +CCc1ccc(CNC(=O)C(C)Sc2ccccn2)s1 +Cc1cc(C(=O)N(C)CC(C)C#N)c2c(C)noc2n1 +CCc1ccc(C2COCCN2S(=O)(=O)CC(C)CC)o1 +Cc1cn2c(CN(C)C(=O)C(C)c3c(C)noc3C)c(C)nc2s1 +COc1ccc(C(C#N)C(=O)C(C)C)cc1C(C)C +Cc1cc2c(cc1C)N(Cc1ccc(F)cc1)C(=O)CN2 +CCC(=O)Nc1cccc(NC(=O)NCCc2nc(C(C)C)no2)c1 +Cc1nc(CNC(=O)c2oc3c(C)ccc(C)c3c2C)oc1C +N#Cc1ccc(Cl)c(NC(=O)Cn2cnnn2)c1 +Cc1cc(CNC(=O)c2ccccc2-c2ncn[nH]2)[nH]n1 +CCOC(=O)N1CCC(C(=O)NCc2cccs2)CC1 +CCOC(=O)CNC(=O)C(C)Sc1ccccc1 +O=C(NCCS(=O)(=O)c1ccccc1)c1cn2cccnc2n1 +O=C(Nc1cnn(CC(F)F)c1)c1cc(-c2cccs2)n[nH]1 +COc1ccc(NC(=O)c2nnn(Cc3cccc(F)c3)c2N)cc1 +Cc1ccn2c(=O)nc(SCC(=O)Nc3cc(C)on3)nc2c1 +Cc1nnnn1-c1cccc(NC(=O)C(C)c2ccsc2)c1 +O=C(COc1ccc2c(c1)OCO2)Nc1ccccc1 +CC(C)(C)c1n[nH]cc1CNc1ccc(CCN2CCOCC2)cc1 +CC(C)Oc1ccc(CC(=O)NCCCO)cc1Cl +COC(=O)c1sccc1NC(=O)CCc1ccccc1 +CCCCc1nc(C)c(C(=O)NCc2cnn(C)c2)s1 +C#CCNC(=O)NC(c1ccccc1)c1ccccc1 +CCOC(=O)CNC(=O)c1ccc(C(C)(C)C)cc1 +COCc1ccccc1CNC(=O)CCc1cccc(F)c1 +CCOC1CCCN(C(=O)Nc2cc(OC)ccc2OC(C)C)C1 +CCOC(=O)C(NC)c1ccc(OC)c(Cl)c1 +CC(NC(=O)C1Cc2ccccc2CN1)C1CCCO1 +CN(C(=O)C12CC3CC(CC(C3)C1)C2)c1ccc(S(C)(=O)=O)cc1 +CCOc1cccc(C(C)NC(=O)NCc2ccco2)c1 +Cc1cc(C)cc(OCC(=O)Nc2ccc(C(N)=O)cc2)c1 +Cc1cc(C)c(CNC(=O)NC(c2ccccc2)C2CC2)c(=O)[nH]1 +O=C(Nc1ccc2c(c1)COC2)c1ccc2nccnc2c1 +Cc1ccc(-n2nnnc2NC(C)c2ccccn2)cc1 +CCOc1ccccc1NCc1nnc2n1CCCCC2 +COc1ccc(C)cc1NC(=O)N1CCN(C)c2ncccc21 +COc1ccc(NC(=O)Nc2nc(C3CC3)cs2)cc1NC(C)=O +COc1c(C)cnc(CNC(=O)N2CCc3ccccc32)c1C +COc1cc(C(=O)N(C)Cc2cc(-c3ccncc3)no2)ccn1 +CN(CC(N)=O)C(=O)Cc1ccc2c(c1)CCCC2 +CC1CN(Cc2ccccc2)CCN1C(=O)c1ccc[nH]1 +CCn1cc(NCc2ccc(Cl)cc2Cl)cn1 +CC1CCCc2sc(NC(=O)CN3CCOCC3)c(C#N)c21 +CC(C)Oc1cccnc1C(=O)NCC(C)(C)c1ccncc1 +O=C1CCCc2[nH]c(=O)c(C(=O)NC(C3CC3)C3CC3)cc21 +CSc1ccc(S(=O)(=O)NCc2ccccc2)cc1 +C=CCN(CC=C)C(=O)CNC(=O)c1ccc(Cl)cc1Cl +CCN(CCO)C(=O)OCC1c2ccccc2-c2ccccc21 +COc1ccc(CNC(=O)CSc2nnc(C)n2N)cc1 +CCCNC(=O)c1cnn(-c2ccc(F)cc2)c1-n1cccc1 +COc1ccc(CNC(=O)CNC(=O)c2ccc(Cl)cc2)cc1 +COc1cc(CNC(=O)NC(C)C)cc(OC)c1O +CN(Cc1cc(Cl)cn1C)C(=O)Cc1cccc(OCC#N)c1 +CC(=O)Nc1ccc(NC(=O)c2ccc(NS(C)(=O)=O)cc2)cc1 +COc1cc(CNC(=O)c2cc(S(C)(=O)=O)ccc2C)ccn1 +O=c1cc(C2CCCN(Cc3cccnc3)C2)nc(-c2ccncc2)[nH]1 +O=C(NCCc1ccc(-n2cccn2)cc1)c1n[nH]c2ccccc12 +COc1ccc(F)cc1NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +COc1cccc(NC(=O)N(CCC#N)C(C)C)c1 +Cc1ccc(NC(=O)NCc2nnnn2-c2ccc(C)cc2)cc1 +CC(=O)c1ccc(S(=O)(=O)N(C)CCc2ccccc2)cc1 +O=C1COC2(COCCN(Cc3ccncc3)C2)CN1c1ccoc1 +CCCC1CN(C(=O)c2cccc(OCC(F)(F)F)n2)CCO1 +CCOC(=O)Cc1csc(NC(=O)c2ccc3ccn(C)c3c2)n1 +COc1ccc(OCCn2c(=O)oc3cc(N)ccc32)cc1 +Cc1nn(C)c2c(NCc3cccnc3)ncnc12 +CC(=O)c1c(C)[nH]c(C(=O)Nc2cccc(-c3nc(C)co3)c2)c1C +COc1cc(CN(C)C(=O)Cc2ccc[nH]2)ccc1SC +COc1ccccc1NC(=O)NC1CCCCC12OCCO2 +O=C(NCC1(c2ccc(F)cc2)CC1)NC1CCCC1 +COCc1ccc(CNC(=O)c2cc(F)ccc2F)cc1 +CC(O)CNc1ncc(Br)c2cccc(Cl)c12 +COc1cccc(CCNC(=O)C(C)n2cncn2)c1 +Cc1cccc(NC(=O)CN2CCOCC2C2CC2)c1C +CCNC(=O)NCC1(c2ccccc2C)CCOCC1 +Cc1nc(-c2ccccn2)cc(N2CCOCC2)n1 +COCCN1CCN(C(=O)NCCCn2nc(C)cc2C)CC1=O +O=C(COc1ccc2ccccc2c1)Nc1cnn(CC2CC2)c1 +Cc1c(Br)cnn1CC(=O)NC(C)C1CCCO1 +O=C(CCCNC(=O)c1c[nH]nc1-c1ccccc1F)NC1CC1 +CN(Cc1ccccc1)C(=O)COC(=O)c1ccccc1Cl +CC1CN(C(=O)Cc2ccc[nH]2)CC(c2ccc(F)cc2)O1 +CCC(=O)c1ccc(OCc2nc3c(c(=O)[nH]c(=O)n3C)n2C)cc1 +O=C(CC1CCCO1)N1CCCC(c2nnc3ccccn23)C1 +CCCSc1cc(C)cc2c1S(=O)(=O)NC2 +CNC1OCC(NC(=O)OCc2ccccc2)CO1 +Cc1nnc(COc2ccc(Br)cc2C)o1 +Cc1ccc2nc(C(C)N3CC(C)OC(C)C3)[nH]c2c1 +Cc1ncccc1OCCOc1ccc2c(c1)CCC(=O)N2 +CC(C)CNS(=O)(=O)c1ccc(C(=O)NC(C)CO)cc1 +O=C(NCc1cn2cc(Br)ccc2n1)C1CC1 +Cc1c(-c2ccc(NC(=O)C(C)C)cc2)nc2ccccn12 +Cc1cc(C)nc(NCC(=O)Nc2ccc(Br)cc2)n1 +Cc1nc2ccccc2nc1N1CCCC(C(=O)NC2CC2)C1 +COc1cc(CCNC(=O)Cc2c(C)nn(C)c2C)ccc1C +Cc1ccccc1NC(=O)Cn1cnc(-c2ccc(F)cc2)cc1=O +CCc1ccccc1NC(=O)CN(c1ccccc1)S(C)(=O)=O +COc1cc(NC(=O)CS(=O)(=O)c2ccccc2)cc(OC)c1 +Cc1c(C(N)=O)nnn1-c1ccc(C(C)(C)C)cc1 +Cc1cccc(C)c1NC(=O)c1ccc(Cl)cc1 +CC1(NC(=O)CCC(=O)NC2CCCC2)Cc2ccccc2C1 +Cc1ccc(C)c(CC(=O)Cc2csc(C)n2)c1 +CCSc1cc(C(=O)Nc2cccc3ncccc23)ccn1 +CN(C)C(=O)c1cc(NC(=O)NCc2cccc3cccnc23)ccn1 +CC(=O)Nc1ccc(C(=O)NC(C)c2ccncc2)cc1 +CC1(C)C(=O)OCCN1C(=O)c1ccc(F)c(F)c1 +O=C(CCc1ccc(OC(F)(F)F)cc1)N1CCC1 +CCOc1cccc(C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)c1 +O=C(NCc1ccnc(OC2CCC2)c1)c1coc2ccccc12 +O=C(c1ccccc1-n1cnnn1)N1CC2CC=CCC2C1 +COC(=O)c1occc1CNc1ccc(OC)nc1 +CNC(=O)COc1ccc(N(C)S(=O)(=O)c2cccs2)cc1 +CC(=O)c1ccc(Oc2ccc(C(=O)Nc3cn[nH]c3)cc2)cc1 +CC(C)C(=O)N(C)Cc1nc(N(C)C)ncc1-c1ccncc1 +O=C(c1c(F)cccc1Cl)N1CCN(CCc2ccccn2)CC1 +N#Cc1nccnc1NCCc1nc2ccccc2s1 +CC(C(=O)Nc1ccccc1)n1nc(-c2ccccc2)ccc1=O +C=CCN(Cc1cccc(C#N)c1)C(=O)c1n[nH]c2ccccc12 +CC(C)n1nccc1NS(=O)(=O)c1ccccc1Cl +O=C(Nc1cccc(CO)c1)c1cnc2ccccc2n1 +O=C(CCn1cnc2sccc2c1=O)N1CCC(O)C1 +O=C(NCc1ccccc1)c1ccc(C(=O)NCc2ccccc2)cc1 +O=C(Nc1ccc(S(=O)(=O)N2CCCCC2)cc1)c1cnccn1 +Cc1ccc(OCC(=O)NCCCn2nc(C)cc2C)cc1 +Cc1ccc(-c2nc(Cn3nc(-c4ccco4)oc3=O)co2)c(C)c1 +O=C(Cc1ccccc1Cl)NCC1CN2CCCCC2CO1 +Cc1nnc(C2COC3CN(C(=O)c4ccsc4)CC32)o1 +Cc1ccc2ncc(C(=O)N3CCN(c4cccs4)CC3)n2c1 +COC(=O)Cn1c(C(C)=O)nc2cc(F)ccc21 +COc1cc(OC)c(NC(=O)NC(C)c2cnn(C)c2)cc1F +Cc1ccc(C(=O)Nc2ccc3nc[nH]c(=O)c3c2)s1 +O=C(Nc1ccc(N2CCCC2)nc1)c1cccc2[nH]ccc12 +CC(C)OCCCNc1ncnc2onc(-c3ccc(F)cc3)c12 +C#CCNC(=O)c1cc(-c2ccco2)nc2onc(C)c12 +O=C(NCc1ccc(Cl)cc1Cl)c1ccncc1F +O=C(NCCCCN1CCOCC1)c1cc2c(s1)CCC2 +CCN1CC(C(=O)NCc2noc(Cc3ccccc3)n2)CCC1=O +COCCNC(=O)c1ccc(NC(=O)c2ccccc2)cc1 +Cc1cccc(OCC(C)NC(=O)c2cccc(-n3cnnn3)c2)c1 +COCCN(C)C(=O)c1cc(C)nc2c1c(C)nn2C +CC(=O)Nn1c(COc2ccccc2)nc2ccccc2c1=O +Cc1cc(F)ccc1NC(=O)Cn1ncc2ccccc21 +CC(C)(C)CCNC(=O)CSc1nnnn1C1CCCCC1 +COc1ccc(S(=O)(=O)NCC2(O)CCc3ccccc32)c(C)c1 +O=C(COC1CCCC1)Nc1ccc(-c2cn3cccnc3n2)cc1 +Cc1cc(N)ccc1NC(=O)C(C)Oc1ccccc1Br +Cc1sc(NC(=O)Cn2c(=O)cnc3ccccc32)c(C#N)c1C +COC(=O)CCCn1c(N)nc2cc(Cl)ccc21 +Nc1cccc2c(C(=O)Nc3ccccc3F)nccc12 +Cn1cc(CCCSc2ccc(F)c(F)c2)cn1 +CCOc1ccc(-c2cc(N)on2)cc1NC(C)=O +COc1ccc(-c2nnc(SCC(=O)NC(C)C(C)C)n2C)cc1 +CNC(=O)c1ccc(NC(=O)NCc2ccc(C)cc2C)c(C)c1 +O=C(c1cccnc1)N1CCOC2CC(COc3ccccn3)CC21 +CCOc1ccc(NS(=O)(=O)c2cccc(C(=O)NC)c2)cc1 +COc1ccc(N)cc1S(=O)(=O)Nc1ccc(Cl)cc1 +COc1cccc(CSc2nc3ccccc3n2CCC#N)c1 +Nc1cc(Br)ccc1NCC1CCCO1 +CN1CCOC(CNCc2ccc3c(c2)CC(C)(C)O3)C1 +CCCCCCn1nnc(S(=O)(=O)CC)c1N +CCCN(CC(F)F)C(=O)c1cccc(OC)c1F +COC(CCc1ccc2nc(C)[nH]c2c1)(OC)OC +Cn1c(C(=O)NCCS(N)(=O)=O)ccc1-c1ccc(F)cc1 +Cn1cc(CN2CCc3cccc(F)c3C2)c(-c2cccnc2)n1 +COc1cc2c(cc1OC)CN(C(=O)Nc1c(C)noc1C)CC2 +COCC(C)NC(=O)Nc1ccc(C(=O)NC(C)C)cc1C +O=S(=O)(NC1CCC(C(F)(F)F)CC1)c1ccc(F)cc1 +COCc1cccc(CNC(=O)N2CCCC(CNC(C)=O)C2)c1 +CCCC(CCC)C(=O)NCc1cc(C)oc1C +CN(C1CCCCC1)S(=O)(=O)N(Cc1ccncc1)C1CC1 +COc1cccc(C2CCN2C(=O)c2ccc3cccc(F)c3n2)c1 +CCCCc1cc(NC(=O)Cn2cnc3c(C)cccc3c2=O)[nH]n1 +CNC(=O)CCNS(=O)(=O)c1ccc(C)cc1 +Cc1ccc2c(CC(=O)OCC(=O)Nc3cc(C)on3)coc2c1 +FC(F)Oc1ccc(C2CC(c3ccccc3)Nc3nnnn32)cc1 +CC(C)C(C)NS(=O)(=O)c1ccc(Cl)c(N)c1 +COc1ccccc1CNC(=O)c1cccnc1N +CCCN(CC(=O)OC)C(=O)Cc1ccncc1 +CN(CC(=O)NCC1CC=CCC1)c1ccc(Cl)cn1 +Cc1noc(C)c1CN1CCOC(Cn2cncn2)C1 +CCOC(=O)COc1cc(OC)ccc1C(C)=O +Cc1cccnc1CNC(=O)NCc1ccnc(OC(C)(C)C)c1 +Cc1cc(C(=O)Nc2ccc3oc(C)nc3c2)[nH]n1 +COC(=O)C1CCN(C(=O)c2cscc2C)c2ccccc21 +COC(=O)C(C)(C)c1ccc(NCC2=CCCOC2)cc1 +CCN(CC)C(=O)c1cccc(-c2cnn(CCC(N)=O)c2)c1 +Cc1ccccc1-c1cnc(NC(=O)NCCCn2ccnn2)s1 +c1ccc(C2(c3nnc(C4CC4)o3)CCOCC2)cc1 +COC(=O)c1ccc(C2OCCc3cc(OC)c(OC)cc32)cc1 +Cc1cc(CN(C)C(=O)c2ccc(-c3ccc(F)cc3)o2)no1 +CCc1nc(CNc2ccccc2C(=O)N2CC(C)CC(C)C2)no1 +O=C(c1ccccc1F)N1CC(S(=O)(=O)c2ccc(F)cc2)C1 +Cc1csc(NC(=O)CC2Oc3ccccc3NC2=O)n1 +COc1ccc(C)cc1CN(C)C(=O)c1ccn(C)c(=O)c1 +O=C(NCc1ccccn1)c1nc[nH]c1C(=O)NC1CCCCC1 +CCN(Cc1cccc(C)c1)C(=O)Nc1ccc(CC(=O)NC)cc1 +Cc1ccc(F)cc1NC(=O)COc1ccccc1F +CCC(CC)C(=O)NCC(=O)Nc1cccc(F)c1 +CCCc1nc(CSc2nnc3n2CCCCC3)no1 +Cc1cc(C)c(NC(=O)NCC(C)(O)CCC(C)C)c(C)c1 +Cc1ccc(C(=O)Nc2ccc3nc(C)sc3c2)cc1 +O=C(NCC(O)c1ccco1)Nc1cccc(C(=O)NC2CC2)c1 +COc1ccc(CNC(=O)c2sc3ccc(F)cc3c2C)cc1O +Cc1cnn(CC2CCCCN2C(=O)c2ccc(NC3CC3)nc2)c1 +CCn1cc(C(=O)N2CCCC(n3cncn3)C2)c(C(C)C)n1 +COc1cc(CCc2cc(C)[nH]n2)cc(OC)c1OC +CC(=O)c1cccc(NC(=O)CSc2ccccc2C)c1 +Cc1nc(NCCS(N)(=O)=O)c2c(CC(C)C)csc2n1 +CCCCCNC(=O)CN1C(=O)C(C)Oc2ccccc21 +CCC1COCCN1C(=O)c1nc2ccc(Cl)cn2c1F +O=S(=O)(NCC#CCOc1cccnc1)c1cccs1 +CCOc1ccccc1CNC(=O)Nc1cc(F)c(OC)c(F)c1 +CC(c1cccnc1)N(C)C(=O)NC(c1nccs1)C1CC1 +CCc1nc(CN2CCN(C(=O)c3ccc(C)c(F)c3)CC2)no1 +CC(NC(c1ccccc1)C(C)C)C(=O)NC1CC1 +Cc1cc2cc(NC(=O)C(C)Sc3nncs3)ccc2[nH]1 +CC1(C)C(C(=O)N2CCN(C(=O)c3ccccc3)CC2)C1(C)C +COc1cc(C(=O)NCc2cc(C)nn2C)c2ccccc2n1 +CC(OC(=O)c1ccc2nccnc2c1)c1ccc(-n2cncn2)cc1 +Cc1nn(C)c(Oc2cccc(F)c2)c1NC(=O)c1ccnn1C +CCOc1cc(C2NC(=O)NC(C)=C2C(=O)OC(C)C)ccc1O +CC(=O)N1CCCc2cc(NC(=O)C(C)c3ccsc3)ccc21 +Cc1ccc(-c2nc3cccnc3n2C(C)C)cc1N +Cc1noc(CCNC(=O)c2c[nH]c3cccc(F)c23)n1 +CCCC(=O)N1CCN(CCc2cn(CC)c3ncccc23)CC1 +Cc1nc2c(C)cccn2c(=O)c1NC(=O)c1cccs1 +CCOc1ccc(F)c(C(=O)N2CC(=O)N(C)c3ccccc32)c1F +CCOc1cc(CNc2nc(C)cs2)ccc1O +O=C(COc1ccccc1)NCCc1nnc2n1CCCCC2 +O=C(n1nnc2ccccc21)n1nnc2ccccc21 +CCOCC1CN(Cc2ccco2)Cc2cn(CC3CC3)nc21 +Cc1ccc2[nH]c(CSc3nc(C)n[nH]3)cc(=O)c2c1 +CC(NC(=O)CN(C)S(C)(=O)=O)c1ccccn1 +CCC1C(=O)NCCN1Cc1cnc(-c2cccnc2)s1 +O=C(NCCc1ccccc1F)Nc1cnn(Cc2ccccc2)c1 +COc1ccc(C(=O)C2CCCN2C(=O)C2CC2)cc1C +CC1CC1CNC(=O)CNC(=O)c1ccc(F)cc1F +COc1ccccc1Nc1nc(N)nc(CSc2nncn2C)n1 +Cc1ncc(CN(C)S(=O)(=O)c2ccc(=O)[nH]c2)s1 +Cc1nc(CNS(=O)(=O)c2cccc(C(=O)NC3CCC3)c2)n[nH]1 +CNC(=O)C(CC(C)C)NC(=O)c1cc2ccccc2c(=O)[nH]1 +CC(=O)c1ccc(OCCCOc2cccc(N)c2)cc1 +COC(=O)C(NC(=O)c1csc2c1CCCC2)C(C)C +CC(=O)N1CCc2cc(C(=O)CNc3ccccc3)ccc21 +CCCC(=O)c1ccc2c(c1)N(CC(=O)N1CCCC1)C(=O)CO2 +CN(Cc1ccccc1)c1cnn(CC2COCCO2)c(=O)c1 +O=C(NCc1cccc(CO)c1)c1cccc(F)c1 +CNC(=O)c1cc(Cl)ccc1NC(=O)COc1ccc(C)cc1C +COc1ccc(-c2cc(N)nc(C)n2)cc1C(C)C +CCNS(=O)(=O)c1ccccc1NCCC(N)=O +COCC(=O)N1CCn2cccc2C1c1ccccc1C +CCCOc1ccccc1-c1nc(N)nc(C)c1C(=O)OCC +Cc1cccnc1NC(=O)CCC(=O)N1CCNC(=O)C1 +O=C(OCC(=O)N1CCOCC1)C(c1ccccc1)c1ccccc1 +CN(CC(=O)N1CCC(C(N)=O)CC1)c1nc2ccccc2s1 +Cc1ccc(CNc2cc3c(cc2Cl)NC(=O)C3)s1 +CCOc1ccc(NC(=O)c2ccc(O)cc2)cc1 +Cc1ccc(C(=O)COC(=O)Cc2ccc3c(c2)OCCO3)s1 +CCOc1ccccc1C(CC(=O)NC(C)(C)C)NC(C)=O +COc1ccc(C(C#N)N(C)C(C)=O)cc1Cl +CCC(C)C(=O)Nc1cccc(N2CCNC2=O)c1 +O=C(CNC(=O)c1cc(-c2ccncc2)nc2ccccc12)NC1CC1 +Cc1cc2ccccc2n2c(=O)n(CCNC(=O)C3CCCO3)nc12 +N#Cc1cccnc1-n1c(C#N)nc2cc(F)ccc21 +Cc1noc(C)c1C(=O)OCc1nc(N)nc(N(C)C)n1 +Fc1ccccc1CNc1ncnc2c1nnn2Cc1ccccc1 +Cc1nc(CC(=O)N(CCC(N)=O)c2ccccc2)cs1 +COc1c(C)cc(C(O)C(=O)NC2CC2)c(C)c1C +O=C(NCCNC(=O)c1ccccc1O)NCc1ccco1 +Cc1nc(Cc2nnc(SCc3ccc(F)c(F)c3)o2)cs1 +Cc1cc(=O)n(C(=O)CSc2nnc(N)n2C)o1 +NC(=O)CCCNC(=O)CCc1ccc(F)c(F)c1 +Cc1cc(C(=O)N(C)CC2CC2)cc(S(=O)(=O)N(C)C)c1C +CCOc1ccc(C#N)cc1NC(=O)C1CCCC1 +CCN(C)C(=O)c1ccc(-c2cc(NCCO)nc3[nH]ccc23)nc1 +COc1ccccc1C(NC(=O)c1cnn(C)c1C)c1ccccn1 +COc1ccc(Cl)cc1C(=O)CNc1cccc(C#N)c1 +Cc1oncc1-c1nc(CCc2ccccc2)n[nH]1 +CCN(C(=O)C(C)N(C)CCC#N)c1ccccc1 +O=C1CCC(C(=O)Nc2ccc(-n3ccnc3)c(F)c2)N1 +COCCCNC(=O)c1nc(C)cc2c(N)cccc12 +CC1=CC=C2C3=C(CCN4C(=O)OC(C)(C)C24C)C(C)=NC13 +COc1ccc(C(=O)COC(=O)c2cccnc2SC)cc1F +COc1cc2sc(NC(=O)Cn3ccnc3)nc2cc1Cl +CNC(=O)c1ccccc1C(=O)C(O)c1ccccc1 +Cc1c(C(=O)NC(C)CCc2ccco2)sc2nc[nH]c(=O)c12 +CC(C)CNC(=O)CSc1nnc(-c2ccc(Cl)cc2)n1N +COc1ccc2c(c1)CCN(C(=O)c1ccc(N)nc1)CC2 +CC1CC1C(NC(=O)c1coc(S(N)(=O)=O)c1)c1ccccc1 +CCc1noc(CN(C)C(=O)NCc2c(C)cc(C)cc2C)n1 +CN(Cc1ccncc1)C(=O)c1ccc(Br)cc1 +COC(=O)N1CCC(CNC(=O)Nc2ccccc2C)CC1 +CS(=O)(=O)N1CCN(c2nnnn2-c2ccccc2)CC1 +C=Cn1cc(CN2CCN(c3cc(CCC)nc(C)n3)CC2)cn1 +COC(C(=O)Oc1ccc(C#N)cc1Cl)c1ccccc1 +Cn1cc(COc2ccc(CO)cc2Br)cn1 +CN(C)C(=O)Sc1ccccc1NC(=O)c1ccc(=O)n(C)c1 +CCC(C)NC(=O)c1cc(C2CC2)nc2c1cnn2C(C)C +CC1CCc2nc(NC(=O)CN(C)S(C)(=O)=O)sc2C1 +CCC(C)NC(=O)COC(=O)c1cc(Cl)c2c(c1)OCO2 +Cc1cc(C)n(CCCN(C)Cc2ccccc2C#N)n1 +CSc1nc(C(=O)N2CCN3C(=O)CN(C)C(=O)C3C2)cs1 +Cn1cnc(CNC(=O)CC2CN(Cc3ccccc3)CCO2)n1 +CCOC(=O)c1cc2ccc(Br)cc2cn1 +CNC(=O)c1cnc(C=Cc2cc(C)c(O)c(C)c2)s1 +Cn1ccnc1Cn1c(CC(F)(F)F)nc2cccnc21 +c1ccc2sc(NCc3nc(C4CC4)no3)nc2c1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)NCCC(C)C +CC(C)c1cc(C(=O)N2CCCC(c3noc(C4CC4)n3)C2)on1 +CC1CCC(=O)N1CC(=O)N1CCN(c2ccc(C#N)cc2)CC1 +FC(F)(F)c1ccc(NCc2cc(N3CCOCC3)ncn2)nc1 +C=CCOC1CCN(c2cc(OC)ncn2)C1Cc1cnn(C)c1 +Cc1cc(C(C#N)Nc2cccc(F)c2)c(C)s1 +COc1cccc(-c2n[nH]c(-c3cccs3)n2)c1 +COc1cccc(C2C(C(N)=O)C(C)=Nc3nnnn32)c1 +CC(=O)NCCNC(=O)Nc1cccc(N2CCCCCC2)c1 +CCOC(=O)CCC(C)NC(=O)c1cc(C#N)cn1C +Cc1cnn(CC2CN(Cc3nnc(-c4occc4C)o3)CCO2)c1 +CCOc1ccc(C2(Cc3ccc(F)cc3)NC(N)=NC2=O)cc1 +NC(=O)c1oc2ccccc2c1NC(=O)c1ccc2ccccc2c1 +O=C(c1ccco1)N1CCc2n[nH]c(-c3ccc(Cl)cc3)c2C1 +O=C(NCc1ccncc1)c1ccc2c(=O)n3c(nc2c1)CCC3 +Cc1cccc(OCC(O)Cn2c(C)nc3ccccc32)c1 +Nc1ccc(Cl)c2c1CS(=O)(=O)N(C1CCCCC1)C2 +CCn1c(SCC(=O)N2C(C)CCCC2C)nnc1C1CC1 +Cc1cc(C(=O)NCC2CN3CCCCC3CO2)c(F)cc1F +CC(C)CC(C)(NS(=O)(=O)c1ccc2c(c1)CCCC2)C(N)=O +Cn1cc(C(=O)NCc2cc(-c3ccccc3)on2)c(C(C)(C)C)n1 +CCNC(=O)c1cc(NCC2CCCOC2)ccn1 +Cn1cc(-c2cc(-c3cccnc3)nc(N)c2C#N)c2ccc(F)cc21 +CCOC(C)c1nc(CN(CC)c2ccccc2)cs1 +CC(=O)Nc1cccc(NCc2ccc(F)cc2Cl)c1 +C1=C(c2ccc3ccccc3n2)Cc2ccccc2N1 +CC1CCC(C)(NC(=O)NC(CCCO)c2ccccc2)CC1 +Cc1oc(C(=O)NC2(c3ccccc3F)CC2)cc1S(N)(=O)=O +Cc1cccc(N2CCN(CC(=O)Nc3c(C)n[nH]c3C)CC2)c1C +COc1cc(CC(=O)Nc2cccc(C(=O)N(C)C)n2)ccc1C +CSc1nc(-c2ccco2)nc(C)c1C(=O)N1CCOCC1C +O=C(NCC(O)c1ccc(F)cc1F)NC1CCCCNC1=O +Cc1cccc(C(N)c2nc(C)c(C(C)C)s2)c1 +Cn1cccc1C(=O)Nc1ccc(CN2CCOCC2)cc1 +CCNC(=O)c1ccc(NC(=O)Cc2c[nH]c3c(C)cccc23)cc1 +Cc1ccc(OCCNC(=O)c2ccc(CNC(N)=O)cc2)cc1 +CCn1nnnc1SCC(=O)c1cccc(OC)c1 +CCOc1ccc(Oc2ccc(NC(=O)Cn3cncn3)cc2)cc1 +CCc1nc(NC(C)Cc2ccsc2)c2cnn(C)c2n1 +Cn1cc(CC2CCN(Cc3n[nH]c(=O)[nH]3)C2)cn1 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1nnnn1C1CC1 +CCC(CC)C(=O)NCc1nnnn1-c1ccc(Cl)cc1 +Cn1cccc(NC(=O)COc2ccc(C(N)=O)cc2)c1=O +CC1CCc2nc3sc(C(=O)Nc4nncs4)c(N)c3cc2C1 +CC(CC(=O)OC1CCCC1)NC(=O)c1ccccc1 +O=C(Nc1ccc(-n2ccnc2)nc1)c1cnccn1 +COC(CNC(=O)c1cc(C)cs1)c1cccc(F)c1 +COc1cccc(C(=O)NC2CC3C(=O)NCC(=O)N3C2)c1C +Cc1cnc(C(=O)Nc2cccc(-n3cccc3)c2)cn1 +CC(=O)c1ccccc1NC(=O)CCc1nc(-c2ccncc2)no1 +CCC(=O)N1CCC2(CC1)CNC(=O)c1cc(C)ccc1O2 +Cc1ccccc1NC(=O)c1cc2n(n1)Cc1ccccc1NC2=O +CC(C)(C)OC(=O)N1CCCC2(CC1)CC2C(F)F +Nc1ccc(Cl)c2c(C(=O)N3CCOCC3)nccc12 +CC(=O)NCCNC(=O)N1CCCCCC1c1ccccc1 +Cc1cc(N)cc2c(CC(=O)NC(C)(C)C)noc12 +O=S(=O)(NC1CCOc2ccccc21)N1CCCCC1 +CCOc1ccc(S(=O)(=O)N2CCCC2)c2ccccc12 +Cc1noc(C)c1C1CCCN1C(=O)CN1CCNC1=O +CC(O)CN1CC2=C(C1=O)C(c1ccc(Cl)cc1)NC(=O)N2 +CC(C)CCOCCN1CCN(C(=O)N2CCOCC2)CC1 +CC(C)c1nnc2sc(-c3ccc(Cl)c(N)c3)nn12 +CC(=O)N(C)CC(=O)NC1CCSc2c(F)cccc21 +Cc1cccc(CCNC(=O)NC(C)Cc2c(C)nn(C)c2C)c1 +CNC(=O)NCCOc1ccc(Br)cc1 +O=S(=O)(Nc1cn[nH]c1)c1ccc(F)c(Br)c1 +NC(=O)C1CCN(C(=O)c2ccc(F)c(F)c2)CC1 +Cc1ccc(N2CC(C(=O)Nc3cc(C)nn3C)CC2=O)cc1 +CCn1cnnc1-c1cccc(NC(=O)c2sc(C)cc2OC)c1 +CC(Nc1ccc2c(c1)oc(=O)n2C)C(=O)NCc1ccccc1 +CC(C#N)CNC(=O)C(C)Oc1ccc(F)c(F)c1 +CC(=O)Nc1ccc(C(=O)CSc2nc(C)c(C)c(C)n2)cc1 +C=CCNC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccccc2)o1 +CC(C)N1CCN(C(=O)c2snc(-c3ccccn3)c2N)CC1 +O=C1Nc2ccccc2OC1CC(=O)N1CCOCC1 +N#Cc1c(F)cccc1NCC(Cc1ccc(F)cc1)C(N)=O +COC(=O)c1ccccc1-n1ncc(C(=O)OC)c1C(F)(F)F +COc1cc(OC)cc(C(=O)NC(C)c2ccccc2OC)c1 +Cc1cccc(CC(=O)Nc2ccc(C)c(N3CCCCC3=O)c2)c1 +COc1ccc(C2CC2C(=O)c2ccccc2)cc1OC +OCCCc1nc(-c2cn(-c3ccc(F)cc3)nn2)cs1 +CCC1C(=O)NCCN1C(=O)NCCOc1ccc2c(c1)OCO2 +COc1cc(C)c(C)cc1S(=O)(=O)NCCc1ccoc1 +CC1CCCC(OC(=O)CN(C)C(=O)c2cccs2)C1 +CCCCCNC(=O)c1c(C)c(N)c(C)[nH]c1=O +Fc1ccc(Oc2ncnc3sccc23)cc1F +COc1ccc(C=Cc2ccc(C#N)cn2)cc1OC(F)F +CC(C)(C)OC(=O)N(CCNc1cn[nH]c(=O)c1Cl)C1CC1 +CCC(C)Oc1ccc(-c2cnn(C)c(=O)c2N)cc1 +CC(=O)c1ccc(C2NCCc3c(O)ccc(F)c32)s1 +Cn1ncc2c(NCCN3CCNC3=O)nc(-c3ccncc3)nc21 +CC(=O)Nc1ccc(OC(=O)c2c(C)nn(-c3ccccc3)c2C)cc1 +COc1ccc(C2CCCN2C(=O)NCc2ccco2)cc1OC +COc1ccncc1NC(=O)CCCn1ccc2cc(Cl)ccc21 +Cc1cc(OCCN2CC(CO)CC2=O)cc(C)c1Cl +CN(Cc1ccc(F)cc1)C(=O)CCNC(N)=O +N#Cc1cccc(NC(=O)N2CCN(C(=O)c3c[nH]c(=O)[nH]3)CC2)c1 +CC(=O)c1ccc(NC(=O)NC2CCN(c3ccccc3)CC2)cc1 +O=C(Nc1onc2c1CCCC2)C1(c2cc(-c3ccco3)on2)CC1 +O=C(c1cc(-c2cccnc2)[nH]n1)N1CCN(c2ccccc2)CC1 +O=C(NCc1ccccn1)N1CCN(c2cnccn2)CC1 +CC(C)OC(=O)C(C)n1c(C2CC2)nc2c(N)cccc21 +CCCCC(=O)Nc1ccn2ncc(C(=O)OCC)c2c1 +O=C(COc1nc(-c2ccccc2Cl)no1)NCC(F)(F)F +Cc1c(C)c2c(c(C)c1Br)OCC(=O)N2 +CC(C)(C)C(C#N)NC(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +COc1cc(C(=O)Nc2nc(C)cs2)cc2c1OCCO2 +Cc1cc2c(=O)nc(-c3cc(OCC(F)F)ccn3)[nH]c2s1 +CC(C)C(C(=O)Nc1ccc2c(c1)COC2)N1CCCC1=O +Cn1nc2n(c1=O)CCN(CC1CCCCC1)C2 +C#Cc1cccc(NCC(=O)NCc2ccc(F)cc2)c1 +Cc1c(C(=O)N2c3ccccc3CC2C(N)=O)cnn1-c1ccncc1 +Cc1cc(C)c(NC(=O)c2ccc(OCC(F)F)nc2)c(C)c1 +O=C(COc1cccc(F)c1)N1CCOCC(CO)C1 +CCOC(=O)Cc1csc2nc(-c3ccccc3OC)cn12 +CC(C#N)CN(C)S(=O)(=O)c1ccccc1C#N +CCn1c(=O)n(CC(=O)Nc2cccc3ncccc23)c2ccccc21 +CS(=O)c1nncn1CC1CCC(C(C)(C)C)CC1 +Cn1c(N)c(N2CCN(C(=O)c3ccccc3)CC2)c(=O)n(C)c1=O +COc1cc(N)cnc1N1CCCc2ccccc21 +CC1=Nn2c(nnc2-c2cnn(-c3ccccc3)c2N)SC1 +CC(CCO)C1(CNC(=O)NCC2CCCO2)CCC1 +Cc1ccc(OCC(=O)N(CC(C)O)CC(C)O)cc1 +CCc1cc(-c2nc(-c3cc(Br)cs3)no2)n[nH]1 +CCNc1ncnc(NCCC2=CCCCC2)c1N +O=S(=O)(NCCc1cccc(Cl)c1)c1cn[nH]c1 +CC(=O)NC1CCCN(S(=O)(=O)C2=Cc3ccccc3CC2)C1 +CCOc1ncccc1C(=O)NCC1CCOC1 +Cc1noc(C)c1CC(=O)Nc1cnc2ccccc2c1 +CCOc1ccc(-c2cc(C(=O)OC)nc(=O)[nH]2)c(C)c1 +O=C(OCC(=O)N1CCCC1)c1csc(CCc2ccccc2)n1 +CCn1c(C)cc(C(=O)NC(C)Cc2ccccc2F)c1C +CCC(CC)C(=O)NC1CCCc2nc(N3CCOCC3)ncc21 +CCc1ccc(C2CCc3nc(C(=O)NC(C)C)cn3C2)cc1 +Cc1ccc(NC(=O)Cn2nc3c(cc2=O)CCCCC3)cc1 +CC(C)(CC1CCOCC1)C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +COCCCNC(=O)C(C)N1C(=O)CCCc2ccccc21 +Cc1ccccc1-c1nnc(SC(C)c2nc(C3CC3)no2)o1 +CC(C)Cc1cc(C(=O)N(C)CC2(CO)CCOCC2)n(C)n1 +Fc1cnc(Nc2ccccn2)nc1Nc1ccccn1 +CN(Cc1cccs1)C(=O)NCc1cnn(C)c1 +Cc1cc(C)c(C(=O)NCc2ccc(C)s2)c(=O)[nH]1 +CC(CC1CCCC1)C(=O)N1CCOC(C(N)=O)C1 +COc1ccccc1-c1cc2nc(C)cc(NC(C)C)n2n1 +Fc1ccc(-n2cc(-c3ccnc(NC4CCCC4)n3)cn2)cc1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NCCN1CCOCC1 +C=CCc1c(OCC(=O)OCC)ccc2nc3n(c(=O)c12)CCC3 +COCCNC(=O)c1nc(Nc2ccc(C)cc2)c2ccccc2n1 +Cn1c(=O)n(CC(N)=O)c(=O)c2ccc(C(F)(F)F)nc21 +COC(=O)c1ccoc1CN1c2ccccc2C(C(N)=O)CC1C +O=C(CCn1ccccc1=O)NC1CC1c1cccc(Cl)c1 +CC#CCSc1nnc(Cc2ccccc2OC)o1 +COc1ccc(CNC(=O)c2ccc(NC(C)=O)s2)cn1 +CCOc1ccc(C(=O)C(C)Sc2nc3ncccn3n2)cc1 +Cc1ccc(C2CCCN2C(=O)c2ccc(-n3ccnc3)nc2)cc1 +CC(=O)Nc1ccc(-n2cnc(C(=O)NCC3CC3)c2)nc1 +Cc1ccc(C(=O)NCC(C)Cn2nc(C)cc2C)cc1 +CCOC1CCN(C(=O)c2cc(-c3ccc(Cl)cc3)n[nH]2)CC1 +CCOc1cccc(C(O)CNc2ccccc2F)c1 +CCC(C)NS(=O)(=O)c1cc(C(=O)C(C)C)ccc1F +Cc1cccc(CN(C(=O)Cc2n[nH]c(=O)[nH]2)C(C)C)c1 +Cc1nc(C2CCCN(C(=O)Cc3cn4ccsc4n3)C2)no1 +CCc1cc2c(SCC(=O)NC(C)C)ncnc2s1 +CC(NS(=O)(=O)c1ccc(C(N)=O)cc1)c1nnc2ccccn12 +COc1cccc(CCC(=O)NC(C)C(=O)N2CCCCC2)c1OC +Cc1n[nH]c(C)c1CCC(=O)Nc1ccc(F)c(Cl)c1 +CC(C)NC(=O)CSc1nc2cc(Cl)ccc2n1C +Nc1nc(-c2ccncc2)ncc1C(=O)NCc1cccnc1 +COc1ccc2c(c1)CN(C(=O)c1cn(C)nc1C(F)(F)F)CC2 +CC(C)n1c(C(=O)NCCCN2CCOCC2)cc2sccc21 +Cc1c(N)c(-c2ccc3c(c2)CCC(=O)N3C)nn1C +CN(Cc1nnc2n1CCCCC2)C(=O)Nc1ccc(Cl)cc1 +COC(=O)N1CCN(Cc2cc(=O)c3cc(C)cc(C)c3[nH]2)CC1 +CCOc1ccc(C(C)=O)cc1CSc1nc(N)cc(N)n1 +CCCC(O)c1ccc2c(c1)C(NC(C)=O)CCC2 +Cc1oc2nc(Cn3cnc(C#N)c3C#N)nc(N)c2c1C +O=C(OC1CCCCCC1)c1cnc(C2CCCO2)s1 +O=C(c1csc(NCc2ccccc2Cl)n1)N1CCCC1 +Cc1cccc2[nH]c(C3CCCN(Cc4ncccc4F)C3)nc12 +Cc1cc(F)ccc1CCNS(=O)(=O)c1c[nH]c(C(C)C)n1 +CCCc1cc(C(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)no1 +CCN1C(=O)CCc2cc(NC(=O)c3ccccc3)ccc21 +Cc1cc(C)c(NC(=O)Cc2ccccc2)c(C)c1 +COc1ccc2c(ccn2CCC(=O)Nc2ccncc2)c1 +CCOC(=O)CC1NCCc2ccc(-c3ccccn3)cc21 +O=c1cc(CS(=O)(=O)c2ccc(O)cc2)nc2ccccn12 +c1csc(-c2nnc3n2NC2CCCCC2S3)c1 +CNS(=O)(=O)c1ccc(F)c(C(=O)OC)c1F +O=C(NCCCCN1CCOCC1)c1ccccc1-n1cccn1 +CC(Cc1ccccc1F)C(=O)Oc1ccc(-n2cnnn2)cc1 +Cc1nc(-c2ccc(=O)n(C)c2)n(-c2cccc(Cl)c2F)n1 +CCc1noc(CC)c1CNC(=O)COc1ccc(C)cc1C +Cc1ccc2onc(CC(=O)Nc3cccc(C)n3)c2c1 +CSc1ccc(NC(=O)Cc2ccccc2F)cc1 +CNC(=O)c1cnc(C)nc1CCNC(=O)CC1CCCC1 +C=CCNC(=O)Nc1ccccc1CN(C)C(=O)OC(C)(C)C +Cc1ccc(S(=O)(=O)N2CCC(C)CC2)cc1N(C)C +CCCCn1c(=O)c2c(OC)ccnc2n(C)c1=O +CN(C)C(=O)N1CCN(C(=O)C2(c3cccc(Cl)c3)CCC2)CC1 +CC(C)CCC(=O)NCCNC(=O)c1ccoc1 +CCNC(=O)c1cccc(NC(=O)Cc2ccc[nH]2)c1 +CC(O)CN(C)S(=O)(=O)c1ccc(F)cc1N +C=CCNc1ncnc(NCc2ccccc2Cl)c1N +CCC(Oc1ccc2c(c1)CCC2)C(=O)N1CCN(CC)CC1 +Cc1ccc(NC(=O)c2cccc(N(C)S(C)(=O)=O)c2C)c(C)c1 +O=C(COc1ccc(F)cc1)N1CCC(Oc2cccnn2)CC1 +CC(=O)NC1CCN(C(=O)C2(C)CN(C)CCO2)CC1 +CCc1nn2c(CNC(=O)c3ccc(C)s3)c(C)nc2s1 +CNS(=O)(=O)c1ccc(NCc2ccsc2)c(N)c1 +COc1ccc(OCCSc2nncn2-c2ccccc2)cc1 +Cc1nc(CNC(=O)CCc2c(C)nn(CCC#N)c2C)c(C)s1 +CCc1ccc2c(c1)nc(CC#N)n2CC(=O)N1CCCC1 +Cc1cc(Br)ccc1NCC(=O)N(CCC#N)CCC#N +Cc1nn(-c2ccccc2)nc1C(=O)N(C)C(C)C1CC1 +COc1cccc(C(=O)N(CC2CC2)CC2CC2)c1F +CC(C)Cc1nc(CN(C)c2nc(C(C)C)nc3c2cnn3C)no1 +O=C(NC1CCCCCC1)c1cncc(Br)c1 +CNC(=O)CCCOc1cccc(Br)c1 +O=C(NCc1ccccc1OC(F)(F)F)c1cnc2ccccc2n1 +CNC(=O)c1cccc(NCC(=O)NCCc2ccc(F)cc2)c1C +CCn1c(C)cc(C(=O)NCC(C)(C)c2ccncc2)c1C +CC1(C(=O)NCc2cnn(Cc3ccccc3)c2)CC1(Cl)Cl +CCOC(=O)C(CO)=c1sc(=Cc2ccc(OC)cc2)c(=O)n1C +O=C(Cn1cccc1)Nc1cnn(C2CCOCC2)c1 +Cc1cc(-c2cc(=O)n(Cc3ccc(F)cc3)nc2C2CC2)on1 +CCCn1nc(C(=O)N(C)Cc2cc(C)on2)ccc1=O +CCNS(=O)(=O)c1cc(S(C)(=O)=O)ccc1Cl +O=C(CNC(=O)c1ccccc1F)Nc1cccnc1 +CC1CN(C(=O)COc2ncnc3sccc23)CC(C)O1 +CCC(C)NC(=O)CCc1ccc(OC)c(N)c1 +Cc1cc(C)c(-c2noc(C)n2)c(NC(=O)c2cc(F)ccc2F)n1 +COc1ccc(COC(=O)CCC#N)cc1Cl +O=C(C(c1ccccc1)c1ccccc1)N(Cc1ccccn1)C1CC1 +CC(Sc1ccc(C(=O)N2CCCC2)cn1)c1ccc(F)cc1 +O=C(CCNC(=O)NCCc1ccccn1)NC1CCCCC1 +CC(NC(=O)Nc1cc(Cl)ccc1F)c1ccc2c(c1)CC(=O)N2 +c1ncc(CN2CCCC3(COCCN(Cc4cn[nH]n4)C3)C2)[nH]1 +CNC(=O)c1ccnc(C(F)(F)F)c1OC1CC1 +COCC(NC(=O)c1ccccc1OC1CCC1)C(N)=O +CC1CCC(CN(C)C(=O)NCc2ncn(C)n2)CC1 +COC(=O)Nc1ccc(NC(=O)C(C)c2ccsc2)cc1 +CCN(C(=O)CS(=O)(=O)c1nccs1)C1CCCCC1 +CN1CCOC(c2noc(Cc3cccc(F)c3)n2)C1 +NC(=O)c1cc(CNC(=O)Nc2ccc(F)cc2)on1 +O=C(NC1CCc2ccccc21)c1ccc(-n2cncn2)nc1 +Cc1ccn(CCNC(=O)CSc2nccc3ccccc23)n1 +CCn1cnnc1CNC(=O)Nc1cc(Cl)ccc1Cl +Cc1cc(C(=O)N(C)Cc2ccc(OC(F)F)cc2)c(C)s1 +CCC1CCCCN1c1ccc(N)cc1S(=O)(=O)N(C)C +O=C(NCc1ncc[nH]1)c1cc(C2CC2)nc2ccc(F)cc12 +COc1ccc(CCC(=O)NCc2c(C)cc(C)[nH]c2=O)cc1OC +N#Cc1ccccc1CNC(C(=O)N1CCOCC1)c1ccccc1 +Cc1cnc(NC(=O)CCC2NC(=O)c3ccccc3N=C2O)s1 +O=C1COc2cc3c(cc2N1)SCCC(=O)N3 +CCN(CC)C(=O)c1ccc(NC(=O)c2ccc(OC)cc2)cc1 +O=C(Nc1ccc(CCN2CCOCC2)cc1)N1CCCC(CO)C1 +CCC(C)(C)NC(=O)C(C)Nc1cccc(NC(C)=O)c1C +Cc1ccc(CNC(=O)c2ccc(-n3nc(C)c(C)c3C)nc2)o1 +NC(=O)c1ccncc1NC(=O)c1cc(F)c(F)c(F)c1 +NC(=O)c1cc(-c2csc(COc3ccccc3)n2)ccc1O +COc1ccc(S(=O)(=O)N(C)Cc2cscn2)cc1Cl +CCC(=O)Oc1ccc2c(C)c(CC)c(=O)oc2c1 +c1ccc(SCc2nc(-c3ccncc3)no2)cc1 +COc1cc(C(=O)Nc2ncccc2C)cc2c1OC(C)C2 +COc1cccc(CNC(=O)c2cccc(N(C)C)c2)c1 +Nc1nccnc1C(=O)OCc1cc(=O)oc2ccc3ccccc3c12 +COc1ccccc1NC(=O)Cc1csc(-c2ccccn2)n1 +N#Cc1nc(N2CCCCC2)nc(N2CCCCC2)n1 +Cc1noc(C)c1C(=O)NCCCS(N)(=O)=O +O=C(CN1CC(Cc2ccccc2)CC1=O)N1CCC(F)(F)CC1 +CC(CCNC(=O)Cc1cn2ccsc2n1)c1ccccc1 +CCn1ccc(NC(=O)c2cccc(-c3nnnn3CC)c2)n1 +CCCC1CN(C(=O)c2ccc(F)c(Cl)c2)CCO1 +O=C(NCc1cccc(NC(=O)C2CC2)c1)c1ccc(F)cc1F +CC1c2ccc(F)cc2CCN1C(=O)c1c[nH]c2ccccc2c1=O +Cc1cc(C(=O)NCCOC(N)=O)cc(C)c1F +CN(CC1COc2ccccc2O1)C(=O)Nc1cccs1 +CCC(C)(C)NC(=O)C1CC(=O)N(CCc2ccccc2)C1 +O=c1[nH]c(C2NCCc3c(O)ccc(F)c32)c(F)c(=O)[nH]1 +CCC(CC)c1nc2c(N)cccc2n1CC(=O)OC +CC(C)OCc1c(C(=O)N2CCCC2)oc2ccccc12 +CCc1ccccc1CNC(=O)c1nccnc1N +O=c1cc(N2CCC3(CC2)OCCO3)c(-c2ccccc2)n[nH]1 +O=C(Nc1ccn(Cc2ccccc2)n1)C1CCCO1 +CN1c2ccc(F)cc2OCC1CC(=O)N1CCCC1 +O=C(OCCc1cccnc1)c1ccc(Oc2cccnc2)cc1 +Cn1cnnc1CNC(=O)c1cccnc1Nc1ccccc1F +COC(=O)CNC(=O)C(C)Oc1ccc(F)cc1 +CC(C)Cc1nc(CN(C)C2Cc3ccccc3C2)no1 +Cc1cccc(NC(=O)c2cccnc2SC(F)F)n1 +Cn1nc2c(c1NC(=O)COc1ccc3ccccc3c1)CCC2 +NC(=O)Cc1ccc(NC(=O)CSc2ccc(F)cc2)cc1 +CCCCN(C)C(=O)CSc1ccc2nnc(C)n2n1 +O=C(c1ccc(-n2cccn2)cc1)N1CCCC1c1ccc[nH]1 +CN(C)C(=O)c1ccc(OC(=O)C=C2CCC2)cc1 +COC(=O)c1sc2nc(Cc3nc(C)cs3)[nH]c(=O)c2c1C +Cc1cc(NC(=O)NCC(=O)Nc2c(C)cccc2C)ccc1F +COc1ccc(C2=Nn3c(nnc(C)c3=O)SC2)cc1OC +CC(=O)c1cccc(NC(=O)c2csc(Nc3ncccn3)n2)c1 +c1ccc(CNc2nc3nonc3nc2N2CCCCCC2)nc1 +CC(C)CCN(C(=O)c1cc(-c2cccs2)n[nH]1)C1CC1 +COc1ccc2nc(N3CC(C(=O)Nc4nccs4)C3)sc2c1 +O=C(CC1OC(=O)c2ccccc21)NCc1ccccn1 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)c1ccc(C)s1 +Cc1[nH]c(C(=O)NCC(C)(C)C(N)=O)c(C)c1C(=O)OC(C)C +Cc1ccc(NCCC(O)c2cccc(N)c2)cc1 +CCCN(CC(=O)OCC)C(=O)c1cc(C)cc(C)c1 +Cc1nc(CNc2ccc(C(F)(F)F)cc2)cs1 +CC(=O)c1ccc(S(=O)(=O)NCc2ccc3ccccc3c2)cc1 +CNC(=O)CN1CCOC2CN(c3nccc(C(F)(F)F)n3)CC21 +CCc1nnc(NC(=O)CC2CC3CCC2C3)s1 +O=C(NCC1(c2cccs2)CCCC1)c1cccnc1 +COc1ccc(CCC(=O)Nc2cc(N3CCCCC3)ncn2)cc1 +Cc1nc(C(C)(C)NS(=O)(=O)c2ccc(F)c(F)c2)sc1C +CNC(=O)CC(C#N)c1cc(Cl)ccc1OC +COc1ccc(Cl)cc1-c1nc2ccccn2c1N +O=C1CCCCN1CC(=O)N1CCC1c1ccccc1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)OCc1ccc(C#N)cc1 +Cc1noc(C)c1CN1CCc2ncnc(C3CCOC3)c2CC1 +Cc1cc(Sc2ncccn2)ccc1NC(=O)CC(F)(F)F +CC1CCCCN1C(=O)Cn1c(=O)n(C)c2ccccc21 +O=C(COC(=O)c1c(Cl)cccc1Cl)NC1CC1 +CCCn1nc(-c2ccccc2Cl)cc(N)c1=O +COc1ccc(C(O)CNC(=O)c2cccnc2)cc1F +Cc1cccn(CCC(=O)Nc2ccccc2N)c1=O +CCOc1ccc(S(=O)(=O)Cc2ncc(C(C)C)o2)cc1 +COC(=O)c1cc(C)ccc1OC(=O)C1CCOCC1 +CCOC(=O)C1N=C(c2cc(OC)cc(OC)c2)OC1=O +CCOC(=O)c1cc(CC)sc1NC(=O)c1ccco1 +CC(=O)NCC(=O)NCC(=O)Nc1ccc(F)c(-n2cccc2)c1 +CCc1nc(CN2CCN(C(=O)c3cccc(Cl)c3)CC2)cs1 +CC1CN(C(=O)c2cc3ccccc3n2C)CCO1 +CCOc1ccc(S(=O)(=O)Nc2cccc(C)n2)c2ccccc12 +COC(=O)Cc1ccc(OS(=O)(=O)c2cccc(C(C)=O)c2)cc1 +Cc1cncc(C(=O)N2CC3CN(S(C)(=O)=O)CCOC3C2)c1 +CCCC1CN(C(=O)C2CCCN2C(=O)c2ccccc2O)CCO1 +CCN1C(=O)c2cccc3c(NC(=O)c4cc(C)on4)ccc1c23 +COc1cc(C#N)ccc1OC(=O)CSc1ccc(F)cc1 +CCNC(=O)CNC(=O)C(C)Cc1cccc(C(F)(F)F)c1 +O=C(Cc1nnc(-c2cccc(F)c2)o1)NC1CC1 +CNS(=O)(=O)c1ccc(NC(=O)CN(C)c2ccccc2)cc1 +Cc1noc(CN2CCN(CCN3CCCC3=O)CC2)n1 +Cc1ccc2oc(SC(C)c3nnc(C)o3)nc2c1 +Cc1c(CCC(=O)Nc2cc(-n3cnnn3)ccc2Cl)cnn1C +Cc1cc2nc(-c3cn(C)nc3C)cc(C(F)(F)F)n2n1 +COc1ncccc1CNC(=O)NCc1ccc2c(c1)OCCO2 +C=CCNc1ccc(CCC(=O)N2CCCC2)cc1 +CC(C)(C)OC(=O)N1CCC(NS(=O)(=O)c2ccccc2)CC1 +CN(c1ccc(F)c(F)c1)S(=O)(=O)Cc1ccccc1 +Cc1c(-c2noc(-c3ccco3)n2)nnn1Cc1ccccc1 +CC(C)(C)c1nc(CNc2cnn(CC(F)(F)F)c2)cs1 +Cc1ccc(C#N)c(N2CCC3C(CCC(=O)N3CCCCO)C2)n1 +Cc1nc(-c2ccncc2)sc1C(=O)N1CCN(C)CC1 +Cc1sc(=O)n(CC(=O)N2CCC(C(N)=O)CC2)c1C +NC(c1nnc(C(O)CO)o1)c1cc(F)ccc1F +Cc1ccc(N2CCNCC2=O)c(Br)c1 +Cc1n[nH]c2cc(-c3ccco3)cc(Br)c12 +CC(=O)Nc1ccc(C)c(S(=O)(=O)N(C)CC2CCCC2)c1 +Cc1ccc(C(=O)Nc2cc3c(cc2C)n(C)c(=O)c(=O)n3C)cc1 +CCCNC(=O)NCc1cccn1Cc1cccc(F)c1 +Cc1cc(CN2CCN(C(=O)Nc3ccc(F)cc3F)CC2)on1 +CCOC(=O)c1ccsc1NC(=O)c1cc(OC)cc(OC)c1 +CCn1nc(C)c2ccn(CC(=O)NC3CCCCCC3)c(=O)c21 +Cc1ccc(NC(=O)N(C)Cc2ccccn2)cc1F +O=C(CC1CCC1)N1CCC(Oc2cccc(Cl)c2)C1 +Cc1cc(NC(=O)NCc2sccc2C)n(C)n1 +COc1cccc(Cl)c1-c1csc(C(N)=O)c1 +CN(C)S(=O)(=O)c1ccc(Cl)c(C(N)=O)c1 +COc1ccc(CCNC(=O)c2cnn(C)c2N)cc1 +O=c1[nH]nc(CN2CCOC(c3nccs3)C2)[nH]1 +CCN(CC1CCCO1)S(=O)(=O)c1ccc(F)c(Cl)c1 +CSc1ncccc1C(=O)NCc1nn(C(C)C)c2ccccc12 +COCCn1cc(NC(=O)NC(C)(C)CO)c2ccccc21 +CCC(C)NC(=O)c1ccccc1NC(=O)C1CCCC1 +CCOc1ccc(C(=O)Nc2cnc3cc(OC)ccc3c2)cc1 +O=C(COc1ccccc1F)NCCNC(=O)c1ccco1 +Cc1nc(SC(C(=O)NC(C)(C)C)C(C)C)oc1C +CN(Cc1ccccc1)C(=O)Cn1ncc2c([nH]c3ccccc32)c1=O +O=c1[nH]c(-c2cccnc2)nc2cc3ccccc3cc12 +O=C(Nc1nc2c(s1)CCCC2)c1cc(-c2ccccc2)[nH]n1 +Cn1ccnc1S(=O)(=O)Cc1cccc2ccccc12 +Cc1cc(C(=O)NCCNC(=O)c2ccccc2)[nH]n1 +Cc1nc2ccccc2c(=O)n1CCCC(=O)NCC1CCCO1 +COCCN1C(=O)c2ccccc2NC1(C)c1ccccc1 +COc1ccc(CCNCc2nnc(-c3ccccc3)o2)cc1 +Cc1cc(CN(C)C(=O)c2cc3ccccc3[nH]2)no1 +CC1Cc2ccccc2N1CCNC(=O)Nc1cccc(C#N)c1 +COc1cc(OC)cc(C(=O)OCC(=O)NC2CC2)c1 +CC(C)c1noc(CCC(=O)OCC2CC=CCC2)n1 +C=CCNc1nc(-c2cc3c4c(c2)CC(=O)N4CCC3)cs1 +COc1ccc(OC(=O)C2CC(=O)N(CC(F)(F)F)C2)cc1 +CC(=O)N1CCC(C(=O)N2CCCCC2C)CC1 +Cc1cc(C)cc(CCNC(=O)NCC(C)CN2CCOCC2)c1 +COc1ccc(F)cc1-c1cc(CO)c(=O)n(C)n1 +O=c1cc(-c2ccc(Cl)cc2)[nH]n1-c1ccccc1 +C=CCOc1ccccc1CN1CCOC(C)(C)C1 +CC(=O)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1 +Cc1cc(-c2ccc(Cl)cc2)n2nc(C)c(C#N)c2n1 +O=C(Nc1cc(F)cc(F)c1)c1ccc(CO)cc1 +CCCn1ncc(C(=O)N2CCN(CCCOC)CC2)c1C +CCC(NS(=O)(=O)c1cnn(CC)c1)c1ccc(C)cc1 +O=C(NCC(c1ccccc1)N1CCOCC1)c1cccc(F)c1 +COC(=O)c1ccc(NCc2ccc(=O)[nH]c2)cc1 +CCN(CC)C(=O)c1cc(C)c(C)c(S(=O)(=O)N(C)C)c1 +CCCOc1ccccc1C(=O)Nc1ccnc2[nH]ncc12 +COC(=O)C1CN(Cc2c[nH]nc2-c2ccc(C)cc2)CCO1 +COCC1CCCN1C(=O)Nc1ccccc1OCc1ccccn1 +Cc1ccnc(-n2nc(-c3ccccc3F)c(C#N)c2N)c1 +NC(=O)NCCCCC(=O)Nc1ccc(Cl)cc1Cl +O=C(NCc1cn2cc(Cl)ccc2n1)C1CC=CCC1 +O=C(Nc1ccc2oc(C3CC3)nc2c1)C1CCOC1 +O=C1NCCCCC1n1cc(-c2ccccc2Cn2cccn2)nn1 +Cc1cnn(CC(=O)N2CCC(C)c3ccccc32)c1 +COc1ccc(C(=O)NCCCO)cc1C(C)C +COc1cccc(CCC(=O)c2cccs2)c1O +COc1cccc(CC(=O)Nc2nnc(C3CCCCC3)s2)c1 +CCn1c(C)nnc1SCC(=O)Nc1ccc(C(=O)OC)cc1 +CCc1ccsc1C(=O)NCc1cscn1 +COc1ccc(OC)c(S(=O)(=O)NC(C)c2ccc(C)cc2)c1 +CCC(C#N)NC(=O)c1cnc(OC(C)C)c(Cl)c1 +Nc1ccccc1SCC(=O)Nc1cccc(Br)c1 +Cn1cccc1C(=O)N1CCOC2C(OCc3ccncc3)CCC21 +CC(=O)Nc1cccc(NC(=O)CCC(=O)c2ccccc2)c1 +COC(=O)C1(NC(=O)Cc2cccc(F)c2)CCCCC1 +COc1cc(C(=O)NC(C)c2ccc(O)cc2)nc2ccccc12 +CC(C)c1cc(C2CCCN2C(=O)c2ccn(C)n2)on1 +CS(=O)(=O)N(CC(=O)NC1CC1)c1ccccc1Br +O=C(NCC(O)c1ccsc1)Nc1ccc(-c2ccccc2)nn1 +CC(C)NC(=O)CCNS(=O)(=O)c1cccs1 +OCCc1ccnn1-c1ccc(C(F)(F)F)cc1 +N#Cc1ccc(NC(=O)N2CCN(C(=O)c3ccoc3)CC2)cc1 +CC(C)(C)NC(=O)c1ccccc1NC(=O)CC1CCCC1 +CCC(CC)c1nnc(NC(=O)N2CCCCC2c2cn[nH]c2)s1 +Cc1nc(C(NC(=O)Cc2ccc[nH]2)c2ccccc2F)no1 +Cc1ccc(C)c(C(=O)COC(=O)c2cc(=O)[nH]c3ccccc23)c1 +Cc1cc(OCCC(=O)N2CCC(O)CC2)ccc1Cl +O=C(Nc1ccnn1C1CCCCC1)c1cccnc1 +CCn1nc(-c2ccccc2S(N)(=O)=O)oc1=O +CC(=O)c1cccc(NC(=O)Cn2c(=O)sc3ccccc32)c1 +Cc1nc(Cn2cnc3cc(Cl)ccc3c2=O)no1 +CNC(=O)c1cccc(CCNCc2ccc(-n3cncn3)cc2)c1 +CC(=O)N1CC(C(=O)NCCOc2ccccc2)C1 +CC(C)COC(=O)c1csc(-c2cnn(C)c2)n1 +Cn1ccnc(NC(=O)c2cn(-c3cccc(Cl)c3F)nn2)c1=O +O=C1CNc2ncnc(Nc3cccc4cccnc34)c2N1 +COc1cc(NCC(=O)N2CC(C)CC(C)C2)c(OC)cc1Cl +Cc1noc2ncnc(N(C)Cc3n[nH]c4c3CCCCC4)c12 +O=C(c1ccc2ccc(Cl)cc2n1)N1CCCCC1CCO +COc1ccccc1CNC(=O)c1scnc1C1CC1 +COc1cccc(C(=O)Nc2ccccc2SC)c1F +CC(CC#N)N(C)S(=O)(=O)c1cc(Br)cnc1N +CC(C)(C)OC(=O)N1CCCC(Oc2cc(C#N)ccn2)C1 +Cc1ccc(C(=O)NCCc2nc3ccccc3[nH]2)s1 +CC(C)Cc1nnc(NC(=O)C2CC=CCC2)s1 +CC(C#N)CSc1ccccc1NC(=O)C1CC=CC1 +CCc1nnc(SCC(=O)Nc2cc(C)ccc2C)o1 +CCC(CC)NC(=O)Nc1nnc(Cc2ccc(F)cc2)o1 +CC1CN(C(=O)CCc2cnn(C)c2)CCC1(C)O +C#CCCNS(=O)(=O)c1ccc(Br)cc1 +O=C(NCCCn1cccn1)c1c[nH]nc1-c1cccc(Cl)c1 +COCC(C)Nc1cc(S(N)(=O)=O)ccc1OC +CCCn1nnnc1CSc1nnc(-c2ccccc2C)n1CC +COC(=O)c1ccc2c(c1)C(c1ccc(O)cc1C)NCC2 +Cc1ccnc(CC(C)N(C)Cc2ccnc(C(C)C)n2)c1 +CCCCNC(=O)c1cc2c(=O)n3cccc(C)c3nc2n1C +OCc1ccc(CN2CC(O)CC2c2nc(-c3ccncc3)no2)o1 +CC(C)(C)n1c(=NC(=O)C2CCC(=O)N2)[nH]c2ccccc21 +Cc1cnc(-c2cccc(NC(=O)c3cccn3C)c2)o1 +CCCCC(COC)NC(=O)Nc1ccc2c(c1)CCC(=O)N2 +C=CCCCOc1cccc(Oc2ncccn2)c1 +CC(=O)N1CCCC1C(=O)NCc1ccc2c(c1)OCCO2 +C=CCNC(=O)CN1CCN(c2ccc(F)cc2)CC1 +Cn1cc(CCCNC(=O)NCCc2nnc3n2CCCCC3)cn1 +N#CCc1ccc(OS(=O)(=O)c2cccc(F)c2)cc1 +CCOC(=O)CCCNC(=O)N1CC(C)OC(C)C1 +COC(=O)C1CCCN(Cc2c[nH]nc2-c2cccs2)C1 +Cc1nc(N(C)C)ncc1C(=O)N1CCCC1c1cc(C(C)C)on1 +CCCCS(=O)(=O)Nc1ccccc1N1CCNC(=O)C1 +Cc1ccc(NC(=O)N(C)CCN(C)C(=O)OC(C)(C)C)cc1F +Cc1cccc2c1C(=O)NC(c1ccc(-n3ccnc3)cc1)N2 +CC(C)n1cccc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +Cc1ccc(C(=O)NCC(=O)Nc2ccccc2)cc1C +COc1ccc(C(=O)NCC(c2ccccc2)C(C)C)nn1 +COc1ccc(S(=O)(=O)Nc2cc(C(N)=O)ccc2C)cc1 +COc1cccc(CNc2cccc(-c3nnnn3C3CC3)c2)c1 +COCCOC1CCN(Cc2cnc(C(C)C)s2)CC1 +Cc1cc(CSc2ccccc2C(=O)OCc2ccccn2)on1 +Cc1nnc(SCC(=O)Nc2ccc(SC(F)F)cc2)s1 +O=C(NC(Cc1ccccc1)C1CC1)c1cn2cccnc2n1 +O=C1c2ccccc2NC(C2CC2)N1c1ccc2c(c1)OCCO2 +CC(=O)N1CCC(NC(=O)NCC2CCCC(C)C2)CC1 +Cc1cccc(C(=O)N2CCN(Cc3ccc(F)cc3)CC2)c1 +C=CC1NCCc2cc(Br)c(F)cc21 +CCSc1nc2n(n1)CC(C(=O)Nc1cccc(Cl)c1)=C(C)N2 +COc1ccc(Cl)cc1C(=O)Nc1ccc2c(c1)NC(=O)CO2 +CCOc1cccc2cc(C(C)NC(=O)C(C)NC(N)=O)oc12 +Cn1cc(CCC(=O)NCCCN2CCOCC2)c2ccccc21 +Cc1cc(CN2CCN(C(=O)Nc3ncc(C)s3)CC2)on1 +COC(=O)c1cc(-c2ccc(O)c(OC)c2)nn1CCO +CCn1ncnc1C1CC(=O)Nc2cc3c(cc21)N(C)C(=O)CO3 +Cc1ccc(C(C#N)N(C)C(=O)C2CCCO2)cc1 +Cc1nc2cc(-c3ccc(O)cc3)ccc2c(=O)[nH]1 +CCOc1ccccc1N1CCN(C(=O)C2CC(=O)N(CC)C2)CC1 +Cc1cc(C)c(N2CCCCS2(=O)=O)c(C)c1 +O=C(NCc1ccco1)N1CCN(c2nccs2)CC1 +O=C(NCC(O)c1ccc2c(c1)CCO2)C1CCC1 +CC(c1cccnc1)N(C)C(=O)CNc1ccc(C#N)cc1 +CC1CN(C(=O)COc2ccccc2)c2ccccc2O1 +Cc1nc(C(=O)C(C#N)c2nc3cc(Cl)ccc3s2)cs1 +Cc1cccc(OCC(=O)NC(C)c2ccc3c(c2)OCCO3)c1C +Cc1cc(C)c(CNC(=O)c2ccc(C)c(-n3cccc3)c2)c(=O)[nH]1 +O=C(Nc1nc(-c2cccc3ccccc23)cs1)c1cc[nH]n1 +O=c1ccnc(-c2ccccc2Br)[nH]1 +CC(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 +CC(Sc1nnc2n1CCCCC2)c1nc2ccccc2c(=O)[nH]1 +O=C(COCC1CC1)Nc1cc(C2CCCC2)nn1-c1ccccc1 +COc1ccccc1OCCCn1c(=O)oc2ccc(C)cc21 +Cc1nc2ccc(NC(=O)C3CCN(CC(F)(F)F)CC3)cc2o1 +CN(C)C(=O)c1cccc(NC(=O)COc2nnc3ccccn23)c1 +CC(C)(CNC(=O)NC1CCOc2ccccc21)N1CCOCC1 +Cc1ccc(N)cc1NS(=O)(=O)c1c(C)noc1C +O=C(CCNC(=O)c1ccccc1)Nc1nccs1 +Cc1ccc(C(=O)c2ccccc2C(=O)N2CCC2)cc1C +OCCCNc1ncc(Br)c2ccc(F)cc12 +CC(C)CC1CCN(C(=O)CCc2ccccn2)C1 +CN(Cc1ccccc1OC(F)(F)F)S(=O)(=O)c1c[nH]cn1 +O=C(NCC(=O)N1CCC(Cc2ccccc2)CC1)c1cnn[nH]1 +COCc1nnc(SCCC(=O)Nc2ccc(Cl)cc2)n1N +COc1c(F)cc(NC(=O)c2cccc(C#N)c2)cc1F +Cc1ccc(OC(=O)CCOCC(C)C)c(C)c1 +COc1ccccc1C(=O)NCCc1ccsc1 +Cc1csc2nc(=O)c3c4c(sc3n12)CCCC4 +CN(C(=O)c1cc2c(=O)n(C)c(=O)n(C)c2s1)C1CCCCC1 +O=C(COc1ccc2c(c1)CCC2)Nc1nncs1 +Cc1ccc2cnn(CCC(=O)NCCn3nc(C)cc3C)c2c1 +Nc1cc(N)nc(SCc2nc3ccccc3s2)n1 +CCOC(=O)c1cccc(NC(=O)c2cccn2C)c1 +NC(=O)C1(Oc2cccc3cccnc23)CCCC1 +CCc1ccccc1NC(=O)Cn1ncc2c([nH]c3ccccc32)c1=O +CCN(C(=O)CN1CCc2ccccc21)c1ccccc1 +Cc1ccccc1-n1ncc(C(C)NC(=O)CCc2ccncc2)c1C +CCc1cc(Br)ccc1NC(=O)c1cc(C)on1 +CN(C)c1ccc(C(=O)N2CC(c3nc(-c4ccncc4)no3)C2)cc1 +NC(=O)c1ccsc1NC(=O)c1ccc(OC(F)F)cc1 +CC(C)(C(=O)N1CCOC(C(F)(F)F)C1)c1ccccc1 +O=C(CCC1CCCOC1)N1CCc2cc(F)ccc2C1 +CCC(=O)N1CCCC(C(=O)N2CCCc3c(C)ccc(OC)c32)C1 +O=C(Cc1ccc(Cl)cc1F)Nc1ccc(N2CCCC2=O)cc1 +CC(C)(Oc1ccc(Br)cc1)C(N)=O +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)OCC1CC=CCC1 +C=CCN1CCC2(CCN(C(=O)N(C)C)CC2)C1=O +CSc1nnc(Cn2nc(C)nc2-c2ccccc2)s1 +Cc1cccc(NC(=O)COc2ccc3c(c2)OCO3)c1C +Cc1ccsc1CN(C)C(=O)Nc1ccccc1N1CCCC1=O +CC1CN(C(=O)c2ccn(C)c2)c2ccccc2O1 +COc1ccc(SCC(=O)Nc2cc(C(C)C)n[nH]2)cc1 +CNC(=O)c1csc(NC(=O)Nc2ccccc2)n1 +Cn1cc(OCc2ccccc2)c(=O)cc1C(=O)NC1CCCCC1 +O=C(COC(=O)Cc1ccccc1)Nc1ccc(Cl)cn1 +CC1CCCN(C(=O)C(Sc2ccc(O)cc2)C(C)C)C1 +Cc1ccc(Br)c(NC(=O)CC#N)c1 +Cc1nc(C)c(C(=O)N2CCN(C(=O)Cc3ccccn3)CC2)s1 +CN(Cc1ccc(C#N)cc1)C(=O)COc1cccc(Cl)c1 +Cc1n[nH]c(C(=O)NCc2ccc(C#N)cc2)c1Br +O=C(NCC1CN2CCCCC2CO1)NC1CCCCC1CO +CC(=O)Nc1cccc(CNC(=O)NCC2CCCC(C)C2)c1 +Cc1cc(CS(=O)(=O)N(C)Cc2ccccc2C#N)no1 +CCn1nc(C)c(CNC(=O)N(C)Cc2cccc(OC)c2)c1C +CCc1nc(CC(=O)Nc2cc(Cl)ccc2O)cs1 +Cc1nc(C(=O)N2CCOCC2C)nn1-c1ccc(F)cc1 +O=C(Cc1ccc(Cl)cc1)Nc1ccccc1O +CN(CCOc1cccc(C#N)c1)C(=O)c1cccc2[nH]ccc12 +O=C(c1ccoc1)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +Cn1cnnc1CNC(=O)CNC(=O)CC(C)(C)C +CCCCS(=O)(=O)c1noc(C(=O)NCC)c1N +CC(C)COc1ccc(C(=O)OC(C)C)cc1N +O=C(Cc1ccc(F)cc1)N(CC1=CC=CC2N=CC=C12)C1CC1 +O=C(COc1cccc(Cl)c1)Nc1nc(-c2ccccn2)cs1 +CC1CCN(C(=O)c2nn(C(C)C)c(=O)c3ccccc23)C(C)C1 +CCCc1csc(NC(=O)NCc2nncn2C2CC2)n1 +COc1cc(NC(=O)c2ccccc2Cl)ccc1N1CCCC1=O +Cc1ccccc1-n1cc(-c2ccnc(N3CCN(C)C(=O)C3)n2)cn1 +CCOc1cccc(CNC(=O)N2CCN(c3nccs3)CC2)c1 +Cc1cccc(C)c1OCC(=O)Nc1ccc(C#N)cc1 +Cc1cc(CN(C)C(=O)NC(C)c2cccs2)no1 +Cc1csc(C(C)NC(=O)C2CCOc3ccccc32)n1 +CCCC(C)C(=O)N1CCn2nc(C(=O)OC)cc2C1 +CCc1ccc(CNC(=O)Cn2nc3ccccn3c2=O)s1 +COC(=O)c1cncc2c(O)n(-c3ccc(OC)cc3)nc12 +COC(=O)Cn1ccc(NS(=O)(=O)c2ccccc2Cl)n1 +CC1Oc2c(N)cccc2N(CC(O)CO)C1=O +O=C(OCC1CCCO1)C1CCCN(C(=O)c2ccc(F)cc2)C1 +CCc1nc(N)n(-c2ncc(C(F)(F)F)cc2Cl)n1 +Cc1cc(C(=O)N2CCOC(c3ccc(C(F)(F)F)cc3)C2)on1 +CCc1ccc(NC(=O)CNC(N)=O)cc1S(N)(=O)=O +COc1ccc(C)cc1C(C#N)CC(=O)NC(C)(C)C +COc1ccc(OC)c(C(C)NC(=O)COc2ccc(C)nc2)c1 +CC(CCc1ccccc1)NC(=O)N1CCC(CC(N)=O)CC1 +CC(=O)c1ccc(NCC(=O)N(C)C2CCCc3ccccc32)cc1 +O=C(NCC(=O)N1CCCCCC1)c1ccc(Br)cc1 +CCn1c(=O)oc2cc(NC(=O)Nc3ccccc3Cl)ccc21 +O=C(OCc1nc2ccccc2s1)c1cc(Cl)ccn1 +CNC(=O)NCC(=O)Nc1cccc(COC2CCCC(C)C2)c1 +Cc1ccccc1-n1cc(C(=O)N(Cc2cccnc2)C2CC2)cn1 +Cc1ccccc1CCNC(=O)c1cccc2cccnc12 +CCOc1ccc2c(=O)ccn(CC(=O)OC(C)C)c2c1 +N#Cc1ccccc1NC(=O)c1cccc(-c2ccoc2)c1 +Cc1cc(C(=O)Nc2ccc(F)cc2)c2c(C)noc2n1 +COc1ccc(NC(=O)NCc2cnc(C)s2)cc1NC(C)=O +CCOc1ncnc2c1CN(CC(=O)NCCC#N)CC2 +O=C(NC1CCN(C(=O)c2ccn3ccsc23)C1)c1cccs1 +CC(C)C(C)NC(=O)CN1CCN(Cc2cccs2)CC1 +Cc1noc(C)c1CCC(=O)Nc1nc2ccc(Cl)cc2s1 +CC(=O)N1CCN(Cc2coc(-c3ccc(F)cc3)n2)CC1 +CC(C)c1ncc(CN2CCOC(C(=O)Nc3ccccc3)C2)cn1 +N#CCC(O)CCOc1c(Cl)cccc1Cl +CCCCn1c(=O)[nH]c(=O)c2c1nc(CO)n2CCC +COc1ccccc1OCC(=O)N1CC2(C)CC1CC(C)(C)C2 +CNc1oc(-c2cc(S(=O)(=O)N3CCCC3)c(C)o2)nc1C#N +Cc1nc(CNC(=O)CSc2ccc(O)cc2)c(C)s1 +N#CCCN(CCC(F)(F)F)Cc1cc(F)c(F)cc1F +CCSc1cc(Cl)ccc1C(=O)N1CCC(n2cccn2)CC1 +COc1ccc(C(=O)N2CCC(Oc3cc(N(C)C)ncn3)C2)cc1 +CC1CN(CC(=O)c2ccc3c(c2)CCCC3)CC(C)O1 +CC(C)Cn1ncc(C(=O)Nc2ccc(C#N)cn2)c1C(F)F +O=C1CCc2cc(OC(=O)Cn3nc4ccccn4c3=O)ccc2N1 +O=C(NCC1CCCO1)C1COC(=O)N1Cc1cccnc1 +COc1ccc(-n2ccc(CNC(=O)NCC(=O)N(C)C)n2)cc1 +Cc1cccc(=O)n1Cc1sccc1Br +CC(=O)c1sc(NC(=O)C23CC4CC(CC(C4)C2)C3)nc1C +Cc1ccc2[nH]nc(C(=O)Oc3ccc4cn[nH]c4c3)c2c1 +N#Cc1nc(N)n(CCCSc2ccccc2Cl)c1C#N +COc1ccc2c(c1)N(C(=O)c1nccc3ccccc13)CCO2 +O=C(CSc1ncccc1-c1nc2ccccc2[nH]1)N1CCCC1 +Cc1nc(NC(=O)C(c2ccccc2)n2cccn2)sc1C +CNS(=O)(=O)c1ccc(NCCC(C)(C)C)cc1OC +CCOCCC(=O)Nc1ccc(F)c(-c2nnc3n2CCCCC3)c1 +CCn1ncc(C(=O)NCc2c[nH]nc2-c2ccc(Cl)cc2)c1C +CN(C)c1cccc(C2NCCc3cc(F)ccc32)c1 +CC1CCN(C(=O)c2ncoc2-c2cccs2)C(C)C1 +CCN1C(=O)N(CO)C2C1N(CO)C(=O)N2CC +CCOC(=O)c1csc(NC(=O)c2cc(F)cc(F)c2)n1 +CCc1cccc(NC(=O)CSc2nc3ccncc3[nH]2)c1 +O=C(CN1CCN(c2ccc(F)c(F)c2)C1=O)Nc1cccnc1 +O=C(Cc1ccccc1F)NCCc1ccc(F)cc1 +O=C(CNC(=O)N(CCO)C1CC1)N1CCCc2ccccc21 +CCCNC(=O)c1ccccc1NC(=O)C(C)(C)CC +O=c1[nH]c(=O)n(CC(O)c2ccc(F)cc2F)cc1Cl +O=C1c2ccccc2NC(c2c[nH]nc2-c2cccnc2)N1C1CC1 +O=C(NCc1ccco1)c1ccn(C2CCCC2)n1 +COC(=O)c1ccccc1NS(=O)(=O)c1ccccc1C#N +O=C(NCc1c(F)c(F)cc(F)c1F)C1Cc2ccccc2CN1 +O=C(CCN1CCOCC1)c1cc2c(cc1Cl)OCO2 +Oc1ccccc1N1CCN(Cc2ccccn2)CC1 +O=C(c1ccncc1)N1CCN(c2cc(-n3cccc3)ncn2)CC1 +CCS(=O)(=O)c1nnn(CC(=O)Nc2ccccn2)c1N +CC(Sc1nncn1C)C(=O)NCc1ccccc1 +CN(CC(=O)NC(C)(C)C)c1ncnc2c1cnn2-c1ccccc1 +O=C(Cc1cccc(F)c1)Nc1cccc(OCC2CCCO2)c1 +COC(=O)CNS(=O)(=O)c1ccc(C#N)cc1 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1ccccn1 +COc1cccc(C(=O)N2CCCN(Cc3cncs3)CC2)c1 +Cc1cccc2nc(CSc3nnc(C(F)(F)F)n3N)cn12 +COC(C)(C)c1noc(CCC(=O)c2ccc3c(c2)CCC3)n1 +CCN(CC)S(=O)(=O)c1ccc(Sc2nncs2)nc1 +O=C(NCc1ccc2c(c1)OCCCO2)NCc1ccccn1 +O=S(=O)(NCc1ccc2c(c1)OCCO2)c1cn[nH]c1 +N#Cc1c(N2CCOCC2)ccnc1Oc1ccc(Cl)cc1 +Cc1cc(Nc2ncnc(-n3nnc4ccccc43)c2N)no1 +CCCc1ccc(C(=O)COc2cccc(N)c2)cc1 +CC(C)C(NC(=O)Nc1ccc(F)cc1)c1nccn1C +CN(Cc1nnnn1Cc1ccccc1)CC1CCCO1 +O=C(COc1ccccc1)N1CCN(Cc2ccco2)CC1 +CCOC(=O)CN1CCC2(CCCCN2C(=O)OC(C)(C)C)C1=O +Nn1c(SCC(=O)NC2CCCCC2)nncc1=O +CC(C)n1ncc2c(C(=O)NCc3ccccc3)c3c(nc21)CCC3 +CCCCN(C)S(=O)(=O)c1ccc(N2CCCC2=O)cc1 +COCCN1CCCC2(CCN(C(=O)Nc3cccc(F)c3)C2)C1=O +O=C(C1COc2ccccc2C1)N1CCC(O)(c2cccnc2)CC1 +OCCNc1nc2sc3c(c2c2nc(-c4ccco4)nn12)CCC3 +O=C1CCC(COC(=O)C2(c3ccc(Cl)cc3)CC2)N1 +CCCN(CCC)C(=O)CSc1n[nH]c(N)n1 +CN(C)c1ccc(C(=O)NCc2ccncc2)cc1 +COc1ccc(Cl)cc1CCNC(=O)NC1CCC(O)CC1 +Cc1cccc(-n2nnnc2SCC(=O)N2CCCCC2C)c1 +O=C(Nc1cccc(CNC(=O)c2ccncc2F)c1)c1ccco1 +O=S(=O)(CC1CCCCC1)N1CCC(CO)CC1 +Cc1noc(CNc2ccccc2S(=O)(=O)N(C)C)n1 +Cc1ccc(NCc2cc3ccccc3[nH]c2=O)c(C)c1 +O=C(NC(CO)Cc1ccccc1)c1nc(-c2ccccn2)no1 +CC(=O)c1c(C)[nH]c(C(=O)Cn2c(C)nc3ccccc3c2=O)c1C +O=C1COc2cccc(OCc3nccn3C(F)F)c2N1 +COC(=O)c1ccc(F)c(Cn2cc(Br)ccc2=O)c1 +Cc1nccn1-c1ccc(=O)n(CCNC(=O)c2ccncc2)n1 +CCC(C)(C)NC(=O)c1cccc(N(C)S(C)(=O)=O)c1 +N#Cc1cc2c(nc1SCC(=O)c1ccccc1)CCCC2=O +COCc1nc(N2CCC(C)CC2)sc1C(C)(C)O +Cc1ccccc1C(C)NC(=O)C(C)S(=O)(=O)c1nncn1C +Nc1oc(-c2ccco2)cc1C(=O)c1cscn1 +CCCc1cc(C(=O)OCC(=O)Nc2cccc(C)c2)[nH]n1 +CS(=O)(=O)N1CCC2C1CCN2C(=O)c1ccc2c(c1)OCO2 +COc1ccc2c(C(=O)NCc3ccccc3)cc(=O)oc2c1 +CCCOc1cc(S(=O)(=O)NCc2ccco2)ccc1Cl +COc1ccc(C(C#N)NC(=O)CC(C)C)c(OC)c1 +Cn1c(-c2nc(C(=O)N3CCNC(=O)C3)cs2)cc2ccccc21 +CCOC(=O)c1ncc(Br)cc1Cl +CN(CC(=O)NC1CC1)C(=O)c1cc(F)c(Cl)cc1Cl +COc1ccc(CNC(=O)CNC(=O)c2nccc3ccccc23)cc1 +NC(=O)c1ccc(C(=O)NCC2COCCO2)cn1 +COC(=O)Nc1cccc(Oc2cc(=O)n(C)c(=O)n2C)c1 +COC(=O)c1cc(OC)ccc1NC(=O)CC1CCCC1 +COC(=O)c1ccc(CSc2nc(-c3ccccc3F)n[nH]2)o1 +CC(=O)c1cc2c(cc1Cl)CCCN2C(C)=O +COc1cccc(C2CCCN2C(=O)COc2ccccc2)c1 +O=C(COC(=O)c1ccc(Cl)cc1)NCc1ccc2c(c1)OCO2 +COc1ccc(C(=O)N2CCC3(CC2)OCCO3)cc1F +CSc1ccc(CNC(=O)c2ccc(F)cc2)cc1 +CC(C)(C)C(NC(=O)c1cccc(S(C)(=O)=O)c1)C(F)(F)F +N#Cc1ccc(C(=O)NCCOc2ccccc2Cl)cn1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1cnn(-c2ccccn2)c1 +Cc1nccc(C(=O)Nc2c(-c3cccs3)nc3ccccn23)n1 +CC(C)C1C(=O)NCCN1C(=O)Nc1cccc(COCC2CC2)c1 +CN1CCC(NC(=O)Cc2cccc(C(F)(F)F)c2)C1=O +Cc1ccc(S(=O)(=O)NCC2CCN(c3ncccn3)CC2)cc1 +COC(=O)C1=C(c2ccccc2)N(C)C(=O)NC1c1cccc(O)c1 +COC(=O)C1(NCc2cc(OC)ccc2OC)CC1 +O=C(Cc1cc(-c2ccccc2F)on1)NCc1cccs1 +Cc1cc(OCC(=O)Nc2ccc(-n3cnnn3)cc2)no1 +CNc1nnc(SCC(=O)c2cc(C)n(C3CC3)c2C)s1 +Cc1noc(C2CCN(C(=O)c3snnc3C)CC2)n1 +O=C1CN(C(=O)Cn2ccnc2)c2ccccc2N1 +CC(C)Oc1ccc2c(C(=O)N(C(C)C)C(C)C)cc(=O)oc2c1 +O=C(Cc1ccn[nH]1)N1CCOC(c2ccc(C(F)(F)F)cc2)C1 +CN(CCN(C)c1ccccc1)C(=O)Nc1ccc2c(c1)COC2 +CCNC(=O)CNC(=O)CCCc1cc(F)ccc1F +CSc1ccc(NC(=O)N(Cc2ccco2)CC2CCCO2)cc1 +O=C1CCN(C(=O)COc2cccc(F)c2F)CC1 +COc1cc(F)ccc1NC(=O)N(Cc1ccco1)CC1CCCO1 +COc1ccc2c(c1)c(C(=O)NCCc1ccco1)cn2C(C)C +Cc1cccc(CN2CCN(c3ncccn3)CC2)c1 +C#CCNC(=O)CCn1c(=O)n(CC)c2ccccc21 +CCN(CCO)C(=O)NCc1ccnc(OC2CCCC2)c1 +Cc1nc(C2CCN(C(=O)CN3C(=O)OCC3C(C)C)CC2)no1 +COCCCNC(=O)N(C)Cc1cccc(C(N)=O)c1 +Cc1cccc(C(=O)N2CCC(c3c[nH]c4ncccc34)CC2)c1O +O=C1CC(C(=O)NCc2ccc(Cl)cc2)C2(CCCCC2)O1 +Cc1cc(Br)ccc1C(=O)NCc1ccc(C(N)=O)cc1 +COC(=O)C1(NC(=O)c2cnc3ccc(C)cn23)CCCCC1 +O=C(CNC(=O)c1ccoc1)NC1CCCCCC1 +CC(c1ccc(O)cc1)N(C)S(=O)(=O)N1CCCC1 +CC(C)CC(=O)c1ccc2c(c1)N(C)C(=O)C(C)CO2 +COc1cc(F)c2c(c1)C(c1ccc(F)cn1)NCC2 +COc1ccccc1CNC(=O)c1ccc(N2CCOCC2)nc1 +CCCC1CN(C(=O)CN(C)c2ncnc3[nH]cnc23)CCO1 +COc1ccccc1CN(C(=O)c1ccccc1OC)C1CC1 +COc1ccc(Cl)cc1NCCC(=O)NCc1ccncc1 +O=C(C1CC=CCC1)N1CCCC1CC(O)c1ccccc1 +CC(OC(=O)c1cccc(Cl)c1Cl)C(N)=O +COc1ccc(S(=O)(=O)NC(C#N)CC(C)C)cc1OC +CCCC(O)c1cc(Cl)cc2c1NC(=O)C2CC +CC(NC(=O)C1CCC(=O)N1)C(=O)N1CCCC1C(N)=O +O=C(CCN1CCOCC1)Nc1cccc2ccccc12 +Cc1ccc(-c2nc(-c3ccc(NS(C)(=O)=O)cc3)no2)cc1F +c1cnc(-c2nc(-c3nc(C4CC4)no3)cs2)nc1 +CCOc1c(Cl)cc(C(=O)NCCOC)cc1OC +CCc1c(C(=O)OCc2nc(C)no2)cnn1-c1cccc(Cl)c1 +CCN(CC(=O)NC(C)C)C(=O)c1c[nH]nc1-c1ccccc1Cl +Cc1noc(CCC(=O)N2CCN(C(=O)c3cc(C)oc3C)CC2)n1 +CC(=O)Nc1cc(NC(=O)c2ccc(C)cc2)ccc1F +O=C(Nc1cccc2ccccc12)N1CCC(O)CC1 +Cc1ccccc1NC(=O)CNC(=O)c1cccs1 +Cc1cc(NCc2ccc(C(=O)N(C)C)cc2)nc(C)n1 +CC1CC1c1ccc(CN2CCOC(c3cnn(C)c3)C2)o1 +Cc1cccc(NC(=O)C2CCCN(c3ncnc4[nH]cnc34)C2)n1 +O=C(c1ccco1)N(Cc1ccccc1)c1ccccn1 +CCCNC(=O)C1(NC(=O)c2cccnc2)CCCCC1 +COc1cc(CNC(=O)c2c(C)noc2-c2ccco2)cc(OC)c1 +CCC(CC)NC(=O)Nc1nnc(Cc2ccc(OC)cc2)o1 +COC(=O)C(C)Sc1nc(C)cc(C(F)(F)F)c1C#N +CC(C)c1nnc(NC(=O)CN2CCc3cc(F)ccc3C2)s1 +Cc1c(C(=O)N2CCCCC2CCc2ccccc2)cnn1C +Cc1cc(NC(=O)C(C)(C)C)sc1C(=O)NC(C)CO +COc1cc(C)nc(N2CCN(C(=O)CCc3nccs3)CC2)n1 +CC(C)NC(=O)CNC(=O)CSc1cccs1 +COc1ccc(CNC(=O)c2cccc(S(C)(=O)=O)c2)cc1 +COC(=O)CCc1ccc(C(=O)OC)cc1Br +O=C(CCn1ccc(=O)[nH]c1=O)Nc1nc2c(s1)COCC2 +Cc1c(NC(=O)c2cnc[nH]2)cccc1C(=O)NC(C)(C)C +CC(Oc1ccc2c(c1)OCCO2)C(=O)NCc1ccccc1Cl +CC(C)COc1ccc(C2Nc3ccccc3C(=O)N2C)cc1 +N#CC(C(=O)C1(c2ccc(Br)cc2)CC1)c1ccccn1 +Cc1cc(=O)c(C(=O)N2CCC2)nn1-c1ccccc1F +C=CCn1c(N)nnc1SCCOc1ccc2c(c1)CCC(=O)N2 +CC(C)c1nnc(CSc2nccn2Cc2ccccn2)o1 +CN(C)S(=O)(=O)N1Cc2cncn2CC(C(=O)NCC2CC2)C1 +c1ccc2c(NCC3CCCO3)nc(-c3ccncc3)nc2c1 +O=C(CCCc1ccc(Cl)cc1)N1CC(c2ccccn2)C1 +CC1(CNC(=O)c2ccc3ncccc3c2)CCOCC1 +CC1CCCC(C)N1C(=O)c1ccc(N)cc1Cl +COCc1nc(C(=O)N2CCCCC2Cn2cc(C)cn2)cs1 +Cc1cccc(C(=O)N2CCC(Oc3nncc4ccccc34)CC2)c1 +O=C(Cc1ccccc1F)NCc1cccc(CN2CCCC2=O)c1 +CSc1ccc(C)cc1C(=O)c1ccc(N)cc1 +CCOc1ncnc2c1CN(Cc1noc(C(C)(C)C)n1)CC2 +CC(C)n1nnnc1SCc1ccc(F)c(Br)c1 +COCCCN=c1c(O)c(O)c1=NCc1ccccc1Cl +Cc1oc(-c2cccs2)nc1CC(=O)NCC(=O)OC(C)(C)C +CS(=O)(=O)NC1CCN(C(=O)Cc2c(F)cccc2F)CC1 +Cn1c(=O)[nH]c(=O)c2c1ncn2CCCc1ccccc1 +CC(=O)c1cccc(S(=O)(=O)N2CC=C(c3ccccc3)CC2)c1 +CCn1c(=NC(=O)c2ccc3c(c2)CCN3C(C)=O)[nH]c2ccccc21 +CCCc1cc(-c2nc(C3CCOC3)no2)cs1 +Cn1cc(CNC(=O)Nc2ccc(NC(=O)C3CCCO3)cc2)cn1 +COc1cccc2c1cc(C(=O)Nc1cccc(C(C)=O)c1)n2C +CCNC(=O)c1ccc(-c2ccc(OCCOC)cc2)nc1 +Cc1c(C(=O)NCc2cccnc2)oc2c1C(O)CC(C)(C)C2 +COc1cccc(NC(=O)CN(C)C(=O)Cc2ccccc2F)c1 +Cc1noc(CN2CCN(C(=O)Nc3ccc(F)cc3C#N)CC2)n1 +N#CCOc1cccc(CC(=O)NC(C#N)C2CCCCC2)c1 +CCc1cc(C(=O)NC2CCCc3ccccc32)cc(=O)[nH]1 +CCCCNC(=O)NCCS(=O)(=O)c1ccc(Cl)cc1 +CN(C)C(=O)CN(Cc1ccon1)c1ccccc1 +O=C(CNC(=O)c1ccccc1F)Nc1ccc(F)c(F)c1F +O=C(Nc1cccc(CNS(=O)(=O)c2cccs2)c1)C1CC1 +CCNC(=O)COc1cccc(NC(=O)N2CCOCC2)c1 +CC1(C)CN(C(=O)c2ccc(-c3ccco3)[nH]c2=O)CCO1 +CCCn1ccc2ccc(NC(=O)NC(C)COC)cc21 +Cc1nc2ccc(NC(=O)c3cc(CC(C)C)n[nH]3)cc2o1 +COc1ccc(-n2cc(-c3ccc(F)c(F)c3)nn2)cc1N +Cc1cc(C)nc(NC(=O)C2CSc3ncc(C)c(=O)n3C2)n1 +CS(=O)(=O)NCCCOCC1CCOCC1 +COc1cc(CNC(=O)COc2ccccc2C(C)(C)C)ccn1 +CC(=O)N(C)CC(=O)NC(c1ccccc1)c1ccncc1 +CCN(CC)C(=O)CSc1nnc(C(F)(F)F)n1N +NC(=O)c1ccc(=O)n(Cc2ccc(Cl)cc2Cl)c1 +FC(F)(F)c1cc(-c2ccccc2)nc(-n2cncn2)n1 +COC(=O)CCSc1nnnn1-c1ccc(OC)cc1 +O=C(NCCc1ccccc1)NCC(O)(c1cccs1)C1CC1 +CC(c1ccccn1)N(C)C(=O)c1cccc(OCC(F)F)n1 +CC(C)CN1C(=O)C(C)(C)Oc2ccc(CO)cc21 +CC1CCCC(CNC(=O)c2cn(Cc3ccccc3)nn2)C1 +COc1ccc(F)cc1COC(=O)Cc1ccc(NC(C)=O)cc1 +CNS(=O)(=O)c1ccc(C(=O)Nc2cc(Cl)ccc2F)cc1 +O=C(Cc1nc2cc3ccccc3cc2c(=O)[nH]1)c1cccs1 +CC(=O)NC(C(=O)Oc1cccc2[nH]ncc12)C(C)C +CCOc1ncccc1NC(=O)Cc1ccccc1Cl +COCCOc1ccccc1CNc1ccc(F)cc1 +COc1cc(C)c(C)cc1S(=O)(=O)N1CCC(C(N)=O)CC1 +COc1cccc(-c2nc(C(=O)OCc3cccnc3)c(C)[nH]2)c1 +Cc1cccc(C)c1NC(=O)c1cccn(Cc2ccccc2)c1=O +O=C(NCc1ncc(-c2ccccc2)o1)Nc1ccc2c(c1)OCO2 +Cc1cc(CS(=O)(=O)N(C)CCn2cccn2)no1 +CCc1[nH]nc(NC(=O)Cc2cccc(Cl)c2)c1C +Cc1ncccc1C(=O)Nc1cc(NC(N)=O)ccc1Cl +CCC(=O)NCC(=O)NC(C)(C)c1nc(C)c(C)s1 +CC(O)c1cc(Cl)c2c(c1)C(NS(C)(=O)=O)CCO2 +COc1cccc(C(=O)Nc2ccc(OCc3nc(C)no3)cc2)c1 +CCC(=O)OCC(=O)Nc1nc(C)c(Cl)cc1Cl +CC(=O)NC(C)C1NCCc2c(F)cc(O)cc21 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)NCCc1ccc(F)cc1 +CC(=O)NC(C(=O)NC1CCCCCC1)C(C)C +Cc1cccc(C2(Cc3ccc(Cl)cc3)NC(N)=NC2=O)c1 +Cn1nncc1CN1CCc2cccc(Br)c2C1 +O=C1CCCN1c1cccn(Cc2c(Cl)cccc2Cl)c1=O +NC(=O)CCCNC(=O)CCc1cc(Br)cs1 +Cc1cccc(C(=O)NCc2nnc3ccccn23)c1O +CN(CC(=O)NCc1nnc2n1CCCCC2)C(=O)c1ccccc1 +Cc1ccc(-c2noc(-c3cc4cc(F)ccc4oc3=O)n2)cc1 +CC(=O)Nc1cccc(C(C)NCCc2cccc3cccnc23)c1 +COCCNC(=O)CN1CC(C)Nc2cc(C)ccc21 +COCCOc1cc(C(=O)N2CCC3(CCC3)C2)nc2ccccc12 +O=C(OC1CCCC1)c1ccc(NCc2nnc(C3CC3)o2)cc1 +COC(=O)N=c1[nH]c2ccc(NC(=O)OC)cc2[nH]1 +Cc1nc(COc2ccc(Cl)cc2)sc1C(=O)NCCCO +CC1C(=O)N(c2ccc3c(c2)CCC3)CCN1C(=O)c1ccccc1 +CCc1nnc(NC(=O)Cc2cnn(-c3ccccc3)c2)s1 +Cc1nnsc1C(=O)Nc1ccc(-c2cnco2)cc1 +COCCN(CCOC)C(=O)Nc1ccc(Cl)cc1 +Cc1ccc(NC(=O)Nc2ccc3c(c2)CCC(=O)N3)cc1 +CC1CN(C(=O)c2cc(C(C)C)nc3ccccc23)CC(C)O1 +CCN(Cc1ccc(OC)cc1)C(=O)CC(C)(C)C +CCOC(=O)c1ccc(NC(=O)CSc2ccc(N)nc2)cc1 +CC(CNC(=O)c1cc2occc2[nH]1)Sc1ccccc1 +CCn1cc(C(=O)Nc2cnn(Cc3c(F)cccc3Cl)c2)cn1 +CCOC1COC2(CCCN(S(=O)(=O)c3cn(C)cn3)C2)C1 +Cc1cc(=O)c(C(=O)NCCCO)nn1-c1ccccc1F +O=C(CSc1ncnc2nc[nH]c12)NC1C2CC3CC(C2)CC1C3 +O=C1CN(c2ccc(CNC(=O)C3CC3)cn2)CCN1 +CN(C(=O)CN1CCn2c(nn(C)c2=O)C1)c1ccccc1 +CC(C)c1ccc(CN2CCN(C(=O)Nc3ccn(C)n3)CC2)cc1 +O=C(Cc1ccc2ccccc2c1)Nc1ccc(N2CCCC2=O)cc1 +Cc1nc(C)c(C(=O)NC2CCc3ccccc32)s1 +CN(C)c1cccc(C(=O)NCc2coc(-c3cccs3)n2)c1 +N#Cc1cnn2c(-c3ccc(-n4cncn4)cc3)ccnc12 +CCOCCNC(=O)N1CCN(c2cccc(C)c2)CC1 +O=C(NCc1ccccn1)c1ccc(Br)c(F)c1 +CCOc1ccc(C(=O)N2CCCCCC2)cc1C +COc1ccc2[nH]cc(CC(=O)OC3CCCC3OC)c2c1 +CC(NS(=O)(=O)N(C)C)c1cccc(NC(=O)c2ccccc2)c1 +CCC(CC)CN(CC)c1ccc(N)c(OC)n1 +COC(=O)c1ccc(C)c(NC(=O)C2CCCO2)c1 +N#CCCOc1ccc2ccccc2c1Br +Cc1ccc2nc(Cc3nc(C)cs3)[nH]c(=O)c2c1 +CC(=O)N(C)CC(=O)N(C)c1cccc2ccccc12 +Cc1nc(-c2nnc(NC(=O)C(C)C)o2)cs1 +CNC(=O)NCC(=O)NCC1(c2ccc(C(C)(C)C)cc2)CCC1 +CCn1cc(NC(=O)c2cccc3ncccc23)cn1 +CC1(C)CC(C(=O)NCCNc2cccnc2)CCO1 +CC(C)NC(=O)CCCn1cnc2ccccc2c1=O +COc1ccc(C2(c3nnc(C4CC4C)o3)CCOCC2)cc1 +CCn1cnnc1CCNC(=O)Nc1ccnn1C1CCCCC1 +Cc1cccc(NC(=O)c2cncc(Br)c2)n1 +CCOCC(=O)Oc1cccc(C(=O)N(C)CC)c1 +Cc1noc(C(OC(=O)c2cscn2)c2ccccc2)n1 +COCCN(c1ncccc1Br)C(C)COC +COc1ccc(-c2ccc(C#N)c(=O)n2C2CC2)cc1Cl +O=C(NCc1ccco1)Nc1ccc(NC(=O)Nc2cn[nH]c2)cc1 +Cc1cc(C(=O)Nc2ccc(F)c(NC(=O)OC(C)(C)C)c2)no1 +C=CCNC(=O)NCc1ccc(Br)cc1 +COc1cccc(CC(NC(=O)Nc2cnccc2C)C2CC2)c1 +COc1ccnc(N2CCN(C(=O)CCCc3nc(C)no3)CC2)n1 +CC(=O)c1ccc(OC(=O)c2cccnc2OCC(F)F)cc1 +Cc1cc(S(N)(=O)=O)cc(C)c1NS(C)(=O)=O +Cc1csc(NC(=O)NCCOc2cccc(Cl)c2)n1 +COc1cccc(-c2nc(-c3cc(N)ccc3OC)n[nH]2)c1 +CN(C)c1nc(NC2CC(=O)N(Cc3ccccc3)C2)ncc1F +O=C(Nc1cccc(OCc2cn3ccccc3n2)c1)C1CCCO1 +Cc1ccc(NC(=O)Cn2cnc3c(cnn3CCO)c2=O)cc1 +Cc1cc(C(=O)N2CCN(CC(=O)N3CCCC3)CC2)no1 +O=C(CSc1n[nH]c(=O)[nH]c1=O)Nc1c(Cl)cccc1Cl +Cn1nc(C(=O)Nc2ccccc2Br)cc1C(F)(F)F +CCCc1c(C(=O)NCc2ccccc2)nnn1-c1ccccc1 +O=c1c(=O)n(-c2ccc(F)cc2)ccn1Cc1ccccc1F +Cc1ccc(C(C)NS(=O)(=O)c2ccccc2)o1 +CC(C)COc1cccc(CNC(=O)Nc2nncs2)c1 +NC(=O)COC(=O)c1c(F)cc(OC(F)F)cc1F +CC(C)n1nc(C(=O)N2CCCCC2C(N)=O)c2ccccc2c1=O +O=C(Cc1ccccc1)NCCC(=O)Nc1ccccc1Cl +CSc1nnc2c(n1)OC(c1ccncc1)Nc1ccccc1-2 +COc1ccc(-c2nc3cc(N)ccc3o2)cc1Br +CN(CCOC(c1ccccc1)c1ccccc1)S(C)(=O)=O +CCCc1cc(SCC(=O)Nc2nccs2)ncn1 +COc1ccc(CN(CCO)C(=O)c2ccc(C#N)cc2)c(OC)c1 +CCN(CC1CC1)C(=O)c1ccc(-n2ncc(C#N)c2N)cc1 +CS(=O)(=O)NC1CCOC2(CCN(C(=O)c3cccs3)C2)C1 +COC(=O)c1ccc(NCC(=O)NCc2ccc(F)cc2)cc1 +C=C(C)COc1cccc(C(=O)NCCNC(C)=O)c1 +CCCc1c(C(=O)NCC2CC2)[nH]c(C)c1C(C)=O +CCOCC(=O)Nc1ccc2c(c1)N(C(=O)C(C)(C)C)CCO2 +NS(=O)(=O)c1ccc(NC(=O)Nc2ccccc2)cc1 +CCCC(=O)NCC(=O)NCC1(c2ccc(F)cc2)CCC1 +O=C(CCc1ccco1)N1CCN(C(=O)Nc2ccc(F)cc2)CC1 +CCN(CC(O)c1cccc(O)c1)C(=O)c1cnc(C2CC2)nc1C +CC(=O)Nc1cccc(C(C)NC(=O)Nc2ccccc2)c1 +CC(=O)Nc1cccc(NC(=O)NCC(C)(O)CCC(C)C)c1 +Cc1ccc(NC(C)c2ccc(OC3CCOCC3)cc2)cn1 +O=C(NC1CCN(C(=O)C2CC2)CC1)C1CCCCC1 +Cc1cc(NCC2CN(C3CC3)CCO2)n2ncnc2n1 +Cc1ncc(CNC(=O)C(C)NC(=O)c2ccccc2)s1 +Cc1oc(-c2ccccc2)nc1Cc1nc(-c2ccc(C#N)cn2)no1 +CCN(CC(=O)N(Cc1ccc(C)o1)C1CC1)c1ccc(F)cc1 +COc1cc(F)c(S(=O)(=O)N(C)c2ccccc2)cc1OC +COCCCNC(=O)COc1cc(Cl)c(Cl)cc1Cl +Cc1ccc(C(=O)NCc2cccc(C(N)=O)c2)c(O)c1C +CCc1noc(CC)c1CC(=O)N=c1[nH]nc2ccccn12 +CCC(=O)N1c2ccccc2CC1C(=O)NCCc1ccc(C)cc1 +O=C(c1cc(C2CC2)on1)N1CCC(c2ccccn2)C1 +Cn1nc(-c2ccc3c(c2)CCCN3)nc1C1CC1 +Cc1ccc(CNc2ccccc2CC(N)=O)c(Br)c1 +Cc1cccc(-n2c(C)c(C)c3c(NCc4ccco4)ncnc32)n1 +CCS(=O)(=O)NCCCNC(=O)NC1CCc2c(F)cccc21 +Oc1ccc(-c2nn(-c3c(F)cccc3F)c3c2CNCC3)cc1 +CC(NC(=O)c1ccoc1)c1ccc(Cl)c(Cl)c1 +CCC(=O)N1CCc2cn(CC(C)C)c3cccc(c23)C1 +COc1cccc(Nc2nc(=O)c(C(C)(C)C)n[nH]2)c1 +CN(C(=O)CNC(=O)OC(C)(C)C)C1CCc2ccccc21 +CNC(=O)CCc1ncc(-c2ccccc2Br)o1 +O=C(Nc1cc(-n2nnnc2C2CC2)ccc1F)c1cnccn1 +CN(C)C(=O)CCNC(=O)NCc1ccc(-n2cccn2)cc1 +CNC(=O)c1cc(C)ccc1NC(=O)c1cc(OC)ccn1 +C=CCOc1c(CN2CCCC(c3nc(C)no3)C2)c(C)nn1C +Clc1ccc(OCc2cccnc2)c(CSc2ncn[nH]2)c1 +O=C(Cn1ncc2ccccc2c1=O)N1CCCC1c1ccccn1 +COc1cn(-c2ccccc2)nc1C(=O)Nc1cc(C2CC2)n[nH]1 +COC(=O)NCC(=O)Nc1ccc(-n2cncn2)nc1 +CCc1cccc(NC(=O)CN(C)S(=O)(=O)c2c[nH]cn2)c1 +CCCCC(=O)N(CCC(N)=O)c1cccc(C)c1 +Cc1cc(C(=O)NC2CCN(C(N)=O)CC2)nn1-c1cccc(F)c1 +Cc1cccc(OCC(=O)Nc2ccc3c4c(c(=O)[nH]c3c2)CCC4)c1 +CC(C)OC(=O)CSc1nnc(-c2ccco2)n1C +O=C(NCCc1ccsc1)c1ccc(Br)cc1 +O=C(NCc1ccccc1CN1CCOCC1)c1cc(C2CC2)on1 +O=C(c1cccc(C(=O)N2CCCCC2)n1)N1CCCCC1 +CC(=O)N1CCc2ccccc2C1CC(=O)OCC#Cc1ccccc1 +NC(=O)CC1CCN(C(=O)CCOCc2ccccc2)CC1 +CCN(CC)C(=O)c1ccc(NC(=O)COc2ccccc2)cc1 +CC(=O)NC(C(=O)N1CCCc2cc(C)ccc21)C(C)C +CC(=O)N1CCC(NS(=O)(=O)c2ccc(F)cc2)CC1 +Cn1cc(CCCSc2nnc(N3CCOCC3)n2C)cn1 +CNC(=O)Cn1ncc2c(C)n(Cc3ccccc3F)c(C)c2c1=O +NC(=O)c1ccc(COCC2CCOCC2)c(N)c1 +O=C(Cc1cc2c(cc1Br)OCCO2)Nc1ccccc1 +FC(F)(F)Oc1ccccc1NCCN1CCOCC1 +Cc1nsc(NC(=O)N2CCN(Cc3ccc(F)cc3)C(=O)C2)n1 +NS(=O)(=O)c1ccc(-c2nc(Cc3ccccc3)no2)cc1 +CCN1C(=O)C(Cc2ccc(F)cc2)c2ccccc21 +CC(C)OC(=O)c1ccc(CN2CCCC2=O)cc1 +CC(=O)Nc1ncc(Cc2ccc(Cl)cc2)s1 +Cc1cc(CNC(=O)c2cn(-c3ccccc3Cl)nn2)c(C)o1 +CS(=O)c1ccc(CNc2ccc3c(c2)COC3)cc1 +Cc1c(Cl)cccc1S(=O)(=O)NC1c2ccccc2CC1O +Cn1cnc(CNC(=O)NCC(C)(C)c2ccccc2)n1 +Cc1ccc2sc(NCCCN3CCOCC3)nc2c1C +Cn1ccnc(NC(=O)COc2ccccc2C(F)(F)F)c1=O +COc1ccc(NC(=O)CN2C(=O)COc3ccccc32)cc1Cl +CC(=O)Nc1ccc(CNC(=O)c2cc(C)ccc2C)cc1 +O=C(NCc1cccnc1OC1CCCC1)c1cc(F)cc(F)c1 +CC(NC(=O)NCCc1cccc(O)c1)c1cccnc1 +CC1(O)CCN(c2ccnc(N)n2)CC1Cc1ccccc1 +COCCCN(C)C(=O)NCc1cnn(-c2ccccc2)c1 +CCOC(=O)CCCNC(=O)N1CCCC1C1CCCC1 +CN(CCNC(=O)NCC(C)(O)c1ccsc1)c1ccccc1 +CN(CCOc1ccc(F)cc1)C(=O)c1nccnc1N +OC1CCN(c2ccnc(NCCc3ccccc3Cl)n2)C1 +CCCNC(=O)c1ccc2c(c1)N(S(C)(=O)=O)CC2 +CC(C)COc1ncc(CNCc2cncs2)cc1Cl +O=C(OCc1nnnn1-c1ccccc1)c1cnns1 +CCCC(O)c1cc(Cl)c2c(c1)C(NC(C)=O)CCO2 +CN(CC(=O)Nc1ccc(Cl)cc1)c1ncccn1 +CN(C)c1cccc(C(=O)Nc2ccc3c(c2)OC(F)(F)O3)c1 +Cc1ccc2c(c1)nc(C(=O)NC1CCCC1)n2C +C=CCNC(=O)CSc1nnc(-c2cn(C)nc2OC)n1C +COCc1ccc(C(=O)NCC(c2ccc(C)o2)N2CCOCC2)o1 +CC(C)CN(C(=O)CN1CCN(c2ccccc2)CC1)C1CC1 +CC(C)CCNS(=O)(=O)c1cc2c3c(c1)CCC(=O)N3CCC2 +Cc1nc(C)c(CC(=O)Nc2cccc(C#N)c2)c(=O)[nH]1 +CC(COc1ccccc1)OC(=O)c1ccc(C(N)=O)cc1 +C=CCNC(=O)NCc1ccc(OC)c(C(=O)OC)c1 +Cc1cc(CNC(=O)C2CC(=O)N(c3ccc(F)cc3)C2)no1 +O=C(N1CC2CCC1C2)C1(c2ccc(F)cc2F)CCOCC1 +CC(C)N(C(=O)COC(=O)c1cnc(-c2ccncc2)s1)C(C)C +COc1ccc(C(CC(=O)NC2CCCCCC2)NC(C)=O)cc1 +COc1cccc(CSc2nnc(-c3ccoc3C)o2)c1 +N#CCn1nnc(CO)c1-c1ccc(F)c(F)c1 +Cc1noc(C)c1-c1ccc(S(=O)(=O)N2CCCCC2)cc1 +O=C(c1ccco1)N1CCC2C1CC(=O)N2c1cccnc1 +COc1ccc(C(=O)NCc2ccccc2S(=O)(=O)N(C)C)cc1 +CC1CN(C(=O)C(C)Sc2nncn2C)C(C)CO1 +CN(CC(=O)Nc1ccccc1)S(=O)(=O)Cc1ccc(C#N)cc1 +COc1ccc(CC(=O)N2CCN(C(C)c3cccnc3)CC2)cc1 +CN(C)C(=O)C1CC1c1ccc(OC(F)(F)F)cc1 +COc1ccc(NC(=O)CC(F)(F)F)cc1OC(C)C +COc1ccc(CN2c3cc(C)ccc3NCC2C)cc1N +CCn1cnnc1-c1cccc(NC(=O)Cc2ccccc2C)c1 +O=C(Nc1ccnc(Sc2ccccn2)c1)c1cn2cccnc2n1 +N#CC1(NC(=O)CSc2ncccn2)CCCC1 +Nc1ccc2c(c1)N(C(=O)c1c(F)cccc1Cl)CCS2 +N#Cc1cc(N2CCOCC2)c2ccc(F)cc2n1 +Cc1nnc(CNc2cc(Cl)c(Cl)cc2Cl)n1C +CCCCN(C)C(=O)Nc1cccc(NC(C)=O)c1C +CCC1CCCC(NS(=O)(=O)Cc2cccc(C#N)c2)C1 +Cn1cc(S(=O)(=O)NCCSc2ccc(F)c(F)c2)cn1 +Cn1cccc1C(=O)OCc1cccc(OCC(N)=O)c1 +CC1CCCCC1N(C)C(=O)CN1CCN(c2ncccn2)CC1 +Nn1c(SCCCO)nnc1-c1ccccc1Br +C=CCCOC(C)C(=O)Nc1cccc(Cl)c1N(C)C +COc1c[nH]c(C(=O)NCCS(=O)(=O)N2CCCC2)cc1=O +CCC(C)N(Cc1ccccc1)C(=O)Nc1ccc(F)c(C(N)=O)c1 +CN(CCC#N)C(=O)CN1CCN(Cc2cscn2)CC1 +Cc1ccc(O)c(C(=O)NCCN2CCOCC2)c1 +O=C(Cn1cnnn1)Nc1ccccc1CN1CCc2ccccc21 +O=C(Cc1ccon1)NCC1(Cc2ccccc2)CCC1 +CC(=O)N1CCN(C(=O)c2ccc(Cl)cc2O)CC1 +CCOC(=O)CNC(=O)c1cccc(Cl)c1N +N#CC(C(=O)c1ccco1)c1nc(N)nc(Nc2ccccc2)n1 +CCCCOc1cccc(NC(=O)c2cc(C(C)=O)c[nH]2)c1 +COc1ccc(Br)c(OC)c1Cl +CCCNC(=O)COC(=O)c1ccc(C(F)(F)F)cc1 +CCOC(=O)CCCNC(=O)N1CCc2ccccc21 +Cc1ccc(C)c(OCC(=O)N2CCN(C(=O)CO)CC2)c1 +CC(NC(=O)Nc1ccc2c(c1)OCC(=O)N2)c1ccccc1 +COC(=O)CN(Cc1ccsc1)Cc1ccc(F)c(F)c1 +O=c1onc(-c2cnccn2)n1CCSc1ccc(F)cc1 +O=S(=O)(Cc1cccc(F)c1)N1CCc2ccc(Cl)cc2C1 +O=C(NC1CC1)N1CCCC2(COCCN(c3nncs3)C2)C1 +Cc1ccc(CCC(=O)Nn2c(C)nc3sccc3c2=O)cc1 +O=S(=O)(c1ccccc1)N(CCCO)c1ccccc1 +O=C(CNC(=O)Nc1ccc(C2CC2)nn1)NC1CCCCC1 +Cc1cc(Cl)ccc1OC(C)c1ccnc2nc(N)nn12 +CCC1CCCC(NC(=O)NCCc2nc(C)no2)C1 +CCN(CC)C(=O)CN(c1ccc(N)cn1)C(C)C +CCOc1ccccc1OC(=O)COc1cccc(C)c1 +Cc1cnn(CC(=O)N2CCN(c3ccc(F)cc3)CC2)c1 +Cn1cc(CN2CCC3(C2)C(=O)N(CC(N)=O)c2ccccc23)cn1 +CN(Cc1ccccc1)C(=O)c1cc(-n2cnnn2)ccc1Cl +Cc1csc(-c2ccc(NC(=O)NCc3cnn(C)c3C)cc2)n1 +NC(=O)c1ccc(COC(=O)c2cccc3ncccc23)cc1 +NC(=O)C1=C(Nc2ccc(Cl)cc2)Oc2ccccc2C1 +N#Cc1c(F)cccc1NCc1ccc(OCc2cccnc2)cc1 +CSc1cncc(N2CCCC(CNC(=O)c3ccccc3)C2)n1 +CCC(CC1CCCC1)C(=O)NCc1ccc(S(N)(=O)=O)cc1 +O=C(NCC1CCCO1)c1ccc(-n2ccnn2)cc1 +Cc1nc(C(=O)Nc2cccc3cnccc23)nn1-c1ccc(F)cc1 +COCc1cccc(C(=O)N(C)Cc2ccc(OC)cc2)c1 +NC(=O)CN(Cc1ccc(Br)cc1)C(=O)C1CCCC1 +O=C(Nc1ccccc1)Nc1ccc(O)cc1Cl +CN(CCc1ccccn1)C(=O)COc1ccccc1 +COc1c2ccc(C(=O)Nc3nnc(C)s3)cc2nn1C +COC(=O)COc1cccc(NC(=O)c2cc[nH]n2)c1 +NC(=O)CC1CCN(c2ccc(F)cc2CO)CC1 +CN(Cc1ncon1)C(=O)c1ccc(Br)cc1 +COc1ccc(OC)c(NC(=O)c2c(Br)cnn2C)c1 +COC(=O)CCNC(=O)C1CCCCN1C(=O)OC(C)(C)C +Cn1nccc1CNC(=O)Nc1ccc(Cl)cc1F +COc1cc(CNC(=O)C(Oc2ccccc2C#N)C(C)C)ccn1 +N#Cc1ccccc1OCC(=O)Nc1sccc1C(=O)NC1CC1 +Cc1c(NC(=O)C(C)n2nc(C(F)F)c(Cl)c2C)cnn1C +COc1cccn(CC(=O)N(C)Cc2cccs2)c1=O +COC(=O)Nc1cccc(C(=O)N2CC(C)Sc3ccccc32)c1 +CC(C)n1ncc2c(C(=O)N3CCC3)cc(-c3ccccc3)nc21 +CC(=O)c1cccc2nc(-c3ccc(N)cc3)oc12 +CCCCc1nc(CS(=O)(=O)c2nccs2)no1 +O=C1CC(c2ccc(F)c(F)c2)c2ncn(-c3cccc(F)c3)c2N1 +COCC(C)NC(=O)C1CCCN(S(=O)(=O)c2ccccc2)C1 +C#CCN1CCC(C(=O)Nc2ccnn2Cc2ccc(C)o2)CC1 +O=C(Cc1ccc(Cl)cc1)NCC1COc2ccccc2O1 +O=C(NCC1(c2ccccc2)CCOCC1)c1ccc(F)c(F)c1 +CCOC(=O)CCC(=O)Nc1cccc(C(=O)N(C)C)c1 +CCN1CC(C(=O)N2CCNC(=O)CC2c2ccccc2)CC1=O +CCc1nc(C)sc1CN1CC(c2cccnc2)C1 +COc1nn(C)cc1C(=O)Nc1ccc2c(c1)CCC(=O)N2 +CC(=O)Nc1cccc(C(=O)OC(C)C(=O)Nc2cccc(C)c2)c1 +O=C(CC(c1cccs1)n1cccc1)N1CCc2ccccc21 +Cc1cc(NC(=O)c2ccoc2)c(C)cc1NC(=O)c1ccoc1 +O=C(c1ccncc1)N1CC(S(=O)(=O)c2ccc(F)cc2)C1 +COc1ccc(NC(=O)NC2CCCC2)cc1N1CCCC1=O +O=C(c1cccc2ncccc12)N1CCN(Cc2cccnc2)CC1 +CC(Oc1cccc(Cl)c1)C(=O)Nc1cccc(C(C)O)c1 +N#Cc1ncn(CC(=O)N2CCCC3CCCCC32)n1 +O=C1CC(c2ccco2)CC2=Nc3ncnn3C(c3ccccc3)C12 +CN(C)C(=O)c1nnc2sc(-c3cccc(F)c3)nn12 +O=C(NCCc1ccoc1)c1ccccc1C(F)(F)F +COCCNc1ncnc(N(C)Cc2ccccc2)c1N +CCCC(NC(=O)Cn1ccnc1)c1ccccc1 +Cc1ccc(C)c(C(=O)N(Cc2ccsc2)Cc2ccco2)c1 +Cc1nn(-c2ccccc2)c(C)c1NC(C)C(=O)NCC(C)C +O=C(c1ccco1)N1CCC2C(CCN2S(=O)(=O)C2CC2)C1 +O=c1[nH]c(=O)n(CCc2ccccc2)c2nc[nH]c12 +COC(=O)CCCN(C)C(=O)Cc1cccc(O)c1 +CC(C)NC(=O)Nc1ccccc1C(=O)NC(C)c1ccncc1 +Cc1ccc2c(c1)CCCN2C(=O)C1(C)Oc2ccccc2NC1=O +CCOc1ccc(C(=O)Nc2sc(C)c(C)c2C(=O)OC)cc1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)Oc1cccc(C(N)=O)c1 +CC(C)(C)NS(=O)(=O)c1csc(C(=O)Nc2ccccc2)c1 +O=C(NCc1cccnc1OC1CCCC1)c1cccc2ncccc12 +Cc1cc(C(=O)NC2CCCCC2)ccc1NC(=O)c1cnns1 +Cc1cc(C)n(-c2nnc(SCC(=O)NCc3ccco3)n2N)n1 +Cc1c(C(=O)Nc2nc(-c3ccccc3)c(C(C)C)s2)cnn1C +Cc1cc(C2CCCN2C(=O)c2cc(-c3ccccc3F)no2)no1 +CN(CCc1ccncc1)Cc1cc(Br)cs1 +C=CCN1CCC2(CCCN(C(=O)CCOC)C2)C1=O +Cc1ccccc1COC1CCN(C(=O)C(C)c2cccnc2)CC1 +O=C(NCC(=O)N1CCCCC1)NC1CCC(O)CC1 +COC1CCC(CC(=O)N2CCc3ccc(Cl)cc3C2)CC1 +CCNc1nnc(-c2cnc(N(C)C)s2)s1 +CCc1nsc(Oc2cncc(C(N)=O)c2)n1 +CCc1noc(CN(C)Cc2nc(C)c(-c3ccc(Cl)cc3)o2)n1 +CC(=O)c1sc(-c2ccccc2)nc1S(C)(=O)=O +Cc1cncc(C2CCCN(Cc3ccn(C)n3)C2)n1 +CCCCn1nnnc1CSc1ccc(F)cc1N +Cc1c(CN(C)CC(F)F)c(=O)n(-c2ccccc2)n1C +Cc1noc(-c2ccncc2)c1C(=O)NC1CCCc2ccccc21 +Cc1ccc(C(N)=O)c(OCC(=O)N(C)Cc2ccccc2F)c1 +CC(C)C1CCCN1C(=O)C1CCN(C(=O)C2CC2)CC1 +CNS(=O)(=O)c1ccccc1N1CCN(C(=O)C2CC=CC2)CC1 +Cc1cccc(S(=O)(=O)Nc2cc(C#N)ccc2C)c1 +NS(=O)(=O)c1cc(Cl)c(OCC2CCCO2)cc1Cl +Cn1nnnc1SCc1cccc(OCC(N)=O)c1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)C1(c2cccc(Cl)c2)CCC1 +Cc1nc[nH]c1-c1nccn1-c1ccc2c(c1)CCC2 +CC(=O)c1cc(C#N)c(Oc2ccc(F)cc2)nc1C +CC(=O)N1CCCC(Cc2ccc(C(=O)NC3CCCCC3)nn2)C1 +Cc1ccc2nc(C(=O)NCCc3nnc(C)s3)cn2c1 +Cn1cnc(CNS(=O)(=O)c2cc(F)cc(F)c2)n1 +COc1ccc(C)cc1NC(=O)CCC(=O)c1ccc(F)cc1F +COc1cnn(-c2ccc(C)cc2)c(=O)c1Br +CCc1nnc(N2CCC3(CC(=O)c4ccccc4O3)C2)o1 +C=C(C)COc1cccc(C(=O)Nc2nc[nH]n2)c1 +CCN(CC1CC1)C(=O)Nc1ccc(C(=O)NC2CC2)cc1 +COCCCNC(=O)c1csc(-c2ccc(OC)cc2)n1 +CCOC1CCCN(C(=O)Cc2nc3nc(C)cc(C)n3n2)C1 +O=C(NC1CCCC1)C1CCN(C(=O)Cc2ccccc2)CC1 +CCN(Cc1cccc(F)c1)C(=O)c1ccc(OC)cc1 +CCCNC(=O)c1cccc(NC(=O)C2CCC2)c1 +CC(C)NS(=O)(=O)c1ccc(NCC(=O)N2CCOCC2)cc1 +CN(CC(O)c1ccc(F)cc1)C(=O)C(C)(C)C +Cc1nn(C)c(C)c1CCC(=O)N1CCCC2(CC1)CN(C)C(=O)O2 +O=C(c1ccc(Cn2cncn2)cc1)N(C1CCCC1)C1CCCC1 +O=C(Cn1ccc2c(nnc3ccnn32)c1=O)Nc1cccnc1 +O=C(NCc1cc(Cl)cc2c1OCOC2)c1ccncc1 +CCc1ccc(C(=O)NCCNC(=O)C2CC2)cc1 +O=C(NC(Cc1ccccc1)C(=O)NC1CC1)C1CC=CCC1 +CC(C)Oc1ccc(C(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1 +COCCNC(=O)Cn1c(-c2ccc(F)cc2)c(C)sc1=O +CCN(Cc1cnn(C(C)C)c1)Cc1c(F)cccc1Cl +Cc1ccc(NCC(=O)Nc2nnc(C(C)C)s2)cc1 +Cc1cccc(CN(c2cccc(F)c2)S(C)(=O)=O)c1 +CC(CNC(=O)Cn1c(C2CC2)nc2ccccc21)N1CCOCC1 +COc1cc(Cl)c(-c2cc(C(=O)OC(C)C)n(C)n2)cc1OC +CCOc1ccc(C(C)(C)C)cc1S(=O)(=O)n1ccnc1 +CCc1ncc(C(=O)NCc2ccc(F)cc2)c(N)n1 +CC(C)Oc1ccc(C#N)cc1NCc1ccccn1 +O=C1CCc2cc(NC(=O)NCc3ccccn3)ccc2N1 +C=CCn1c(SCc2ccccn2)nc2sc(C)c(C)c2c1=O +CCc1nnc(NC(=O)CCn2c(C)csc2=O)s1 +COc1ccccc1OC1CCN(C(=O)c2ncc[nH]2)CC1 +CC(C)c1nc2cc(Br)ccn2c1CO +O=C(c1cccnc1NCC1(CO)CC1)N1CCc2ccccc21 +CCOC(=O)c1[nH]c(C)c(C(=O)Nc2ccc(Cl)cc2F)c1C +Cc1cc2c(cc1C)N(CCC#N)CC1(CCCC1)N2 +CC(C)(C)OC(=O)NCCNC(=O)C(C)(C)c1ccccc1F +CC(C)NC(=O)Nc1ccc2c(c1)N(C(=O)C(C)(C)C)CCO2 +CCN(C(=O)CS(=O)(=O)c1nncn1C(C)C)c1ccccc1 +c1ccc2oc(NCc3ccc(-n4ccnc4)nc3)nc2c1 +CN(c1cccnn1)C1CCN(C(=O)c2scnc2C2CC2)CC1 +O=C(C1CCC1)N1CC=C(c2c[nH]c3ncccc23)CC1 +Cc1nc(-c2ccccc2)nc(O)c1CC(=O)OC(C)C +CC(Sc1nnc(N)n1C)C(=O)N1CCCCCC1 +COc1ccc(Cl)cc1N(C)C(=O)c1ccc(F)nc1 +COc1c(O)cc2c(c1OC)C(c1ncccn1)NCC2 +COc1ccccc1CN(C)C(=O)CCNC(=O)Nc1ccccc1 +CCCCOCCCN1Cc2ccc(N)cc2C1=O +COc1cccc(OCCNC(=O)C2CCCN2C(=O)C2CC2)c1 +O=C1NCCN1C1CCN(c2nc(-c3ccccc3Cl)no2)CC1 +CC(=O)Nc1cccc(NC(=O)c2c(Cl)cccc2Cl)c1 +Cc1nc(C2(NC(=O)Cc3c[nH]c4c(C)cccc34)CCCC2)no1 +COc1ccc(S(=O)(=O)NCC2CCOC2)cc1Cl +COc1ccc(-c2nnco2)cc1Br +O=C(NCC1CC1)c1cc(Cl)ccc1NCc1nc(C2CC2)no1 +Cc1ccc(CC(=O)NC(c2ccccc2)c2nccn2C)cc1 +CCN(C(=O)CCc1ccccc1N)C(C)COC +Cc1oc(C2CCC2)nc1C(=O)NCC1CCCCC1 +C=CCn1c(SCCOCC)nc2ccccc21 +CN(Cc1cccc(Cl)c1Cl)C(C(N)=O)c1ccccc1 +COCCN1CCn2c(nc3cc(C(=O)NC(C)C)ccc32)C1 +COc1ccc(-c2cc(CO)nn2C(C)C(C)=O)cc1C +CC(C)C(C#N)OC(=O)CCSc1ccccn1 +CCc1cc(N2CCN(c3cccc(C)c3C)CC2)n2ncnc2n1 +Cc1cc(C(=O)NCc2cccc(NC(=O)C3CCC3)c2)n(C)n1 +Cn1cc(C(=O)NCCS(=O)(=O)c2ccc(Cl)cc2)cn1 +Cc1ccc(C(C)n2ccnc2-c2cnc(-c3cccs3)nc2)nc1 +NC(=O)C1CN(C(=O)NCc2ccc(Cl)cc2)CCO1 +Cn1nc(-c2ccccc2)cc1C(=O)N1CCC(Cn2cccn2)CC1 +COc1ccnc(NC(=O)C2CC23CCOCC3)c1 +CC(C)(C)NS(=O)(=O)c1ccc(C(=O)Nc2ccccc2F)o1 +COC(=O)c1cn(CC(=O)Oc2cccc(C)c2)c2ccccc12 +CC(Sc1ccccc1Cl)C(=O)NC1CCCNC1=O +Cc1ccc(NC(=O)COC(=O)c2cc(-c3ccco3)[nH]n2)cc1 +COCCCNC1=NS(=O)(=O)c2cc(Cl)ccc2N1 +Cc1ccc(C(C)NC(=O)c2c(C)noc2C(C)C)s1 +O=C(CCn1ccccc1=O)N1CCOC(C(F)(F)F)C1 +N#Cc1ccc(N2CCN(C(=O)c3ccc(F)cc3)CC2)c(F)c1 +CCCS(=O)(=O)NCC(C)(C)N1CC(C)OC(C)C1 +Cc1nc(CN2CC3(CCN(C(=O)C4CC4)CC3)OCC2=O)cs1 +Cc1nc(-c2ccc(Br)cc2)nn1CC(N)=O +Cc1[nH]ncc1-c1nn2c(Cc3ccccc3)nnc2s1 +COCCNC(=O)c1cn2ccnc(-c3ccccc3)c2n1 +O=C(Cn1c(=O)[nH]c2ccccc21)NCc1cccc2ccccc12 +CC(=O)N1CCN(C(=O)C2CCCN2C(=O)Cc2cccs2)CC1 +COc1cc(CN(C)C(=O)c2oc(C)nc2C)ccc1OC(F)F +Cc1cc(NC(=O)CNC(c2ncccc2C)C(C)C)n(C)n1 +CCOC(=O)N1CCN(CCSc2ccccc2)CC1 +O=C1CCC(C(=O)NCCC2CC3CCC2C3)N1 +N#CCCC(C#N)CN1CCC(n2c(=O)[nH]c3ccccc32)CC1 +O=C(NCCCO)Nc1ccc(Cl)c(Cl)c1 +CN(CC1CCC1)C(=O)NCc1nccn1CC(F)(F)F +O=S(=O)(c1ccc(-c2ccn[nH]2)o1)N1CCCC2(CCOC2)C1 +O=C(CCc1ccccn1)Nc1cccc(F)c1F +O=C1CN(C(=O)C2CN(c3ccccc3)CCO2)CCN1 +CC(=O)N1CCN(C(=O)CCNc2cccc(F)c2C#N)CC1 +CCCC1CN(C(=O)c2cnc3[nH]nc(C)c3c2)CCO1 +Cc1ccccc1NC(=O)NCCN(C)C(=O)OC(C)(C)C +COc1cccc(C(C#N)NC(=O)COc2ccccc2)c1 +O=C1CN(C(=O)C2CCCN(C(=O)Nc3cccs3)C2)CCN1 +CC(C)COC(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1 +O=C(Cn1c(=O)[nH]c2ccccc21)NC(c1ccccc1)c1ccco1 +Cc1ccc(OC(C)C(=O)NCc2nc3ccccc3[nH]2)cc1 +COc1ccc(CN(C)Cc2cnc(C3CC3)s2)cc1O +O=C(NC1CCCCC1)c1n[nH]c2c1CCc1ccccc1-2 +CN(Cc1cccc(C#N)c1)C(=O)c1csc(-c2cccs2)n1 +CCCc1nc(CS(=O)(=O)c2nnc(NCC)s2)cs1 +CC(C)CC(=O)N1CCN(c2cc(N3CCCC3)ncn2)CC1 +Cc1cc(C)nc(CNC(=O)c2ccc(S(N)(=O)=O)cc2)n1 +COCCCNS(=O)(=O)c1cc(OC)c(C)cc1C +CC(=O)N(Cc1ccco1)C1(C(=O)NC2CCCC2)CCCCC1 +O=C(NCc1cccc2c1OCO2)c1ccc[nH]c1=O +CCOc1ccc(-c2cn3c4ccc(N)cc4nc3n2C)cc1OC +CCCNc1nc(-c2sc(CC)nc2C)cs1 +CC(=O)Nc1ccc(C)c(NCC(=O)NCc2ccc(F)cc2)c1 +COc1ccc(Cl)cc1N(C)C(=O)c1cnc2ccccn2c1=O +Cn1nnc(C#N)c1-c1ccc(C(F)(F)F)cc1 +CS(=O)(=O)c1ccc(NCC(=O)N2CCCC2)cc1 +Cc1cc(C2CCCN(C(=O)c3ccc(C)n3C)C2)n[nH]1 +Clc1ccccc1CN(Cc1cccnc1)CC1CCCO1 +COc1cccc(CCC(=O)Nc2cc(C)nn2C)c1 +Cc1cc(C)c(C#N)c(SCC(=O)N(C)Cc2ccc(F)cc2)n1 +NC(=O)N1CCCC1COC(=O)c1csc(Nc2ccccn2)n1 +FC(F)(F)Cn1cc(NCc2ccn(Cc3ccccc3)c2)cn1 +CC(C)(C)C(=O)NCc1nc(-c2cc(Br)cs2)no1 +O=C(Nc1ccc2c(c1)CCC2)c1ccc(=O)[nH]c1 +Clc1ccc(Cc2nnc(-c3cccnc3)o2)cc1 +O=C(c1ccc(F)cc1)N1CCNCC1c1nc2ccccc2[nH]1 +CCc1ccc(CNCC2(c3cccc(F)c3)CCOC2)nc1 +COc1ccc(C(=O)CCN2CCN(C(C)=O)CC2)cc1 +Cc1cc(C)cc(C2(C(=O)NCc3ccoc3)CC2)c1 +O=C(CCc1ccc2c(c1)OCO2)Nc1cccnc1 +Cc1ccc(C(=O)NC(c2cccc(F)c2)c2nccn2C)cc1 +CN(CCO)C(=O)Nc1ccc(C(=O)NC2CCCCC2)cc1 +N#Cc1cccc(NC(=O)COC(=O)CNC(=O)c2ccco2)c1 +CCCCNC(=O)c1nn(-c2ccc(Cl)cc2)c(=O)n(C)c1=O +COc1ccc(CNC(=O)c2ccc(C)cc2C)cn1 +CC(=O)Nc1cc(F)c(S(=O)(=O)NC2CCCC2)cc1Cl +Cc1cc(C)cc(OS(=O)(=O)c2cccc(C(=O)N(C)C)c2)c1 +Cc1ccc(C(C#N)N(C)C(=O)OC(C)(C)C)cc1 +CCN(CC(=O)NC)C(=O)c1csc(-c2ccc(Cl)cc2)n1 +N#Cc1ccc(N2CCC(Sc3cc(C#N)ccn3)C2=O)cc1 +COc1cc(C(=O)OCc2ccc(C#N)cc2)cc(OC)c1OC +O=C(Nc1cn[nH]c1)N1CCCC1c1cccc(Cl)c1 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)NCC(F)(F)F +CCCCOc1ccc(S(N)(=O)=O)c2ccccc12 +CCC1CCCCC1NC(=O)C1CCN(c2cnccn2)CC1 +CCCN(C)C(=O)Nc1cccc(OC(F)F)c1 +COCCCn1ccc(NC(=O)N(C)C(C)c2ccccc2F)n1 +COc1ccc(C(=O)Nc2ccccc2N2CCNC(=O)C2)cc1 +Cc1ccc(C(=O)Nc2cccc(S(N)(=O)=O)c2)c(C)c1 +O=C(Nc1nnc(C(F)F)s1)N1CCOCC1C1CC1 +O=C1CN(C(=O)c2csc(Nc3cccc(Cl)c3)n2)CCN1 +Cn1ccnc(NC(=O)C2CC2c2ccc(Cl)c(Cl)c2)c1=O +CCc1[nH]c(C(=O)Nc2ccccc2)c(C)c1C(=O)OC +COCCn1cnnc1SCc1noc(-c2cccs2)n1 +O=C(NCC1CC(=O)N(c2ccc(F)cc2)C1)Nc1ccc(F)cc1 +CCOC(C)C(=O)N1CCC(OCc2ccc(F)cc2)CC1 +Cn1c(=O)c2cn(Cc3ccc(Cl)cc3)cc2n(C)c1=O +Cc1nc(C)c(CC(=O)Nc2nc3ccccc3[nH]2)c(=O)[nH]1 +CCn1cc(CN(C)C(=O)Nc2ccccc2Cl)cn1 +CCC(CC)NC(=O)c1ccc(-n2cncn2)cc1 +O=C(CCc1cccnc1)NC(c1ccc(F)cc1)C1CC1 +CCCn1c(SCCC(N)=O)nc2sc3c(c2c1=O)CCC3 +Cn1cc(Cl)cc1C(=O)N1CCN(CCc2cccs2)CC1 +CC(C)c1ccccc1OCC(=O)Nc1ccc(O)cc1 +Cc1cc(C(=O)Oc2ccc(F)cc2)nc2c1c(=O)n(C)c(=O)n2C +Cc1ccccc1C(O)CN1CCN(c2ccc(F)cc2)CC1 +CSc1ncccc1C(=O)N1CC(=O)Nc2ccccc21 +Cc1sc(-c2ccn[nH]2)cc1NC(=O)c1ccc(C#N)cc1 +CC(C)c1ccc(NC(=O)NCCNC(=O)c2cccnc2)cc1 +CCN(CCO)c1nc(C)nc2sc(C)c(C)c12 +CCC(C)NC(=O)CCC(O)c1ccc(F)cc1 +CC(C)N1CCOC2CN(Cc3ccco3)CC21 +CNS(=O)(=O)c1cc(C(=O)C(C)C)ccc1C +CC(=O)N1CCN(CC(O)c2ccc3c(c2)OCO3)CC1 +O=C(c1ccsc1)N1CC2CCN(C(=O)c3ccco3)C2C1 +CC(Nc1nc(-c2ccncc2)nc2ccccc12)c1nncn1C +Cc1noc(C)c1CCC(=O)N1CCN(c2ccc(F)cc2)CC1 +CCCNC(=O)c1cccc(NCC(=O)N2CCCCCC2)c1 +Cn1cc(CCNC(=O)COc2ccc(Cl)cc2)c2cccnc21 +Cc1ccsc1C1CCN(C(=O)c2cccc3c2OCC3)CC1O +Cc1ccc(Br)cc1S(=O)(=O)N1CCOCC1 +COc1c(C)cnc(CSc2nc3ccsc3c(=O)n2C)c1C +Cc1ccc2c(c1)c(N1CCCC1=O)c(C(=O)NC1CC1)n2C +COC(=O)CC(C)NC(=O)Cc1cc(Cl)ccc1OC +CC(C(=O)N(C)C(C)C)N1CCN(Cc2nccn2C(F)F)CC1 +Cn1c(=O)c(=O)n(CC(=O)N2CCCCC2)c2ccccc21 +CC12CCC(C(=O)N3CCc4ccccc43)(CC1=O)C2(C)C +CCc1cc(N(C)Cc2nc(-c3cccnc3)no2)n2nccc2n1 +CN1C(=O)CCc2cc(NC(=O)Cc3ccsc3)ccc21 +Cn1c(=O)ccn(CC(=O)Nc2cc(C(F)(F)F)ccc2F)c1=O +Cc1cc(-n2c(C)cc(C(=O)N(C)CCc3ccccn3)c2C)no1 +CCc1cccc(NC(=O)Cn2ccc(=O)[nH]c2=O)c1 +Cc1ccccc1NC(=O)NCC1CCN(c2cnccn2)CC1 +COc1cc(C(=O)N2CCN(c3ccccc3OC)CC2)on1 +CCC(NC(=O)c1ccc(C)cc1)c1ccccc1 +O=C(NCCNC(=O)c1ccc(F)cc1F)c1ccc(F)cc1 +CCCN(C)C(=O)C(C)NC(=O)c1ccccc1Cl +CCc1noc(C2CCN(C(=O)c3cc(C)on3)CC2)n1 +CC(C)NC(=O)N1CCN(c2ncnc3sccc23)CC1 +O=C(Nc1cccc(C(=O)NC2CC2)c1)c1ccc(-n2ccnn2)cc1 +CCN(Cc1ccccc1)C(=O)CNC(=O)Nc1c(F)cccc1F +CNc1nc(C(=O)N2CCCCC2CCc2cccs2)cs1 +Nc1c(-c2ccncc2)nsc1C(=O)Nc1nccs1 +CCOc1ccc(S(=O)(=O)N2Cc3cncnc3C2)cc1F +CNC(=O)NCC(=O)Nc1cc(C(C)(C)C)nn1C(C)(C)C +COc1ccc(C2CCCN2C(=O)c2cccn2C)cc1OC +COc1cc(OC)cc(C(=O)N2CC(C)OC(C)C2)c1 +CNC(=O)CCCc1nc2cccnc2n1CCOC +CCCNC(=O)CN1CC(C)Nc2cc(F)c(F)cc21 +O=C(CSc1nncc2ccccc12)N1CCc2ccccc21 +Cc1cc(COC(=O)c2cccc(OCc3csc(C)n3)c2)on1 +COC(=O)C1CCCCN1C(=O)c1c(F)cccc1F +CC(C)CC(=O)Nc1cc(Br)ccc1-n1cncn1 +O=C(NCCNC(=O)c1ccco1)c1ccc(N2CCNC2=O)cc1 +Cc1ccc(CCNC(=O)C2CCN(c3ccc(F)cc3)C2=O)cc1 +CC(C)c1csc(NC(=O)NC2CCCN(c3cnn(C)c3)C2)n1 +COc1ccc(C#CCNC(=O)Cn2c(=O)oc3ccccc32)cc1 +CCC1(CC)C(OC)CC1OC(=O)c1ncn(-c2ccccc2)n1 +N#CCc1ccc(NC(=O)N2CCN(C(=O)c3ccoc3)CC2)cc1 +NC(=O)c1ccc(F)c(CNCCc2ccccn2)c1 +O=C(NCc1ncn[nH]1)C12CC3CC(CC(C3)C1)C2 +CS(=O)(=O)NCCCNC(=O)NC1CCOc2ccccc21 +COc1ccc(C)cc1CN(C)C(=O)CSc1ccncc1 +COc1ccnc(N(C)Cc2nccn2CC(F)(F)F)n1 +Cc1ccc(F)cc1NC(=O)c1ccc(C(F)(F)F)nc1 +Cc1csc(C2CN(c3ncnc4sccc34)CCO2)n1 +CC(C)c1ccc(C2CCCN2C(=O)CN2CCCCC2=O)cc1 +CCC1C(=O)Nc2c(C)cc(C(O)C3CCCO3)cc21 +Cc1ccc2c(CC(=O)OCCOC(C)C)coc2c1 +Cc1noc(C)c1CCC(=O)NC1CCCc2ccccc21 +COc1ccc(OC)c(NC(=O)C2CCCN(C(=O)NC3CC3)C2)c1 +CC(C)C(=O)Nc1cccc(CNC(=O)c2ccc(F)cc2)c1 +CCOC(=O)CSc1nnc(-c2ccncc2)n1C1CC1 +C=CCc1ccc(OC(=O)C2CC(=O)Nc3ccccc32)c(OC)c1 +CC(c1ccccc1)C(CO)NS(=O)(=O)c1ccc(C#N)cc1 +COC(=O)Cn1nc2cc(-c3ccc(OC)cc3)nc(C)n2c1=O +CC(Nc1ccn(-c2ccccc2)n1)C1CCOC1 +CCCCS(=O)(=O)N1CC=C(c2c[nH]c3ncccc23)CC1 +CCCC1CN(C(=O)CCc2ccc(OC)c(F)c2)CCO1 +Cc1ccccc1-c1ccc(=O)n(CC(=O)NCc2ccco2)n1 +Cc1cccc(C2(C(=O)NC(C)C(=O)NC3CCCC3)CC2)c1 +COCCN(C(=O)NC(C)C)C1CCN(c2nc(C)cc(C)n2)CC1 +CSc1nc2ncc3c(=O)n(-c4ccc(C)cc4)ccc3n2n1 +Cc1cc(C)c(S(=O)(=O)NCCN2CCOCC2)c(C)c1 +COC(=O)c1ccccc1S(=O)(=O)N1CCOCC1 +CCc1nc2nnc3c(=O)n(-c4cccc(C)c4)ccc3n2n1 +O=C(NC1CCN(S(=O)(=O)C2CC2)CC1)c1ccc2[nH]ccc2c1 +CCn1nc(NC(=O)C(C)C)c2cc3cc(C)ccc3nc21 +OCCn1c(-c2cccc(-c3cc[nH]n3)c2)nc2ccccc21 +COc1cccc(-c2nc(Cn3ccnc3)cs2)c1OC +O=c1c(C(F)(F)F)cccn1CC1CCCCC1 +COC(=O)CCn1c(CCO)nc2ccc(F)c(F)c21 +O=C(c1cccc2c1OCO2)N1CCN(c2ccc(O)cc2)CC1 +Cc1cc(NCc2ccc(OCc3ccccc3)cc2)n2ncnc2n1 +C=CCN1C(=O)c2ccccc2NC1c1ccc(F)cc1 +COC(=O)c1ccc(COc2ccc(F)cc2F)o1 +CC(C)(C)C(O)CNc1nc2ccccc2c(=O)[nH]1 +O=C(NCc1nnc2ccccn12)c1cc2ccccc2oc1=O +COc1cccc(C2NCCc3cc(C)c(O)cc32)n1 +CCOC(=O)CN1C(=O)C(C)N=C(c2ccccc2)c2ccccc21 +O=C(NCc1ccccn1)c1nc(CC(=O)N2CCOCC2)no1 +FC(F)CN(Cc1cccc(-c2ccncc2)c1)C1CC1 +C#CCCCOC(=O)c1cccc(-n2cccn2)n1 +Cc1nnc(SCC(=O)Nc2ccc(C(C)(C)C)cc2)n1N +Cc1noc(C)c1CC(=O)Nc1cccc(Br)c1 +O=C(Nc1ncc(Cc2ccccc2)s1)c1cc[nH]n1 +Cc1cccc(OC2CCN(c3ncnc4c3cnn4C)CC2)c1C +COC(=O)CCNC(=O)C1CC(=O)N(Cc2ccccc2)C1 +Cc1cc(C(=O)N(C)C2CCc3ccccc32)c(C)o1 +CN(Cc1ccc2nonc2c1)C(=O)CCCc1cn[nH]c1 +CC(=O)Nc1ccc(N2CC(C(=O)N3CCCCC3C)CC2=O)cc1 +O=c1[nH]nc(Cc2ccncc2)n1-c1ccccc1Oc1ccccc1 +CC(=O)c1c[nH]c(C(=O)Nc2ccc(Oc3ccccc3C#N)cc2)c1 +Cn1ccc(CNC(=O)C2(c3ccc(F)cc3F)CCCC2)c1 +Cc1csc(CSc2nnc(-c3ccccc3)n2C)n1 +COc1ccc(OC)c(CC(=O)NCc2cccnc2)c1 +O=C(NC1CCCCC1O)c1cccc2ncccc12 +CN1C(=O)CCC(C(=O)NCc2ccco2)C1c1cccc(F)c1 +CC(C)CC(C)NC(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +CCNC(=O)CN(CC)S(=O)(=O)c1cccc2cnccc12 +O=C(CNC(=O)C1(c2ccc(Cl)cc2)CCC1)N1CCCC1 +Cc1c(Cl)cc(C(=O)NCCc2cnccn2)cc1Cl +CC(C)OCCCNC(=O)C1CCCN(c2cn[nH]c(=O)c2)C1 +NC(=O)N1CCCN(C(=O)CCc2ccc(Cl)c(Cl)c2)CC1 +c1cncc(CCCNc2ccc3cn[nH]c3c2)c1 +CCOc1ccc(CC(=O)Nc2ccc(N)c(C)n2)cc1 +COc1ccc(CCNC(=O)CNC(=O)c2cc(C)nn2C)cc1 +COc1cc(NC(=O)NCc2ccc3c(c2)OCO3)cc(OC)c1 +CC(C)(C)c1ccc(C2CCn3nc(N)nc3C2)cc1 +OCC(O)C1NCCc2c(F)ccc(C(F)(F)F)c21 +CC(NC(=O)c1cc(F)ccc1F)C(C)N1CCOCC1 +CCOC(=O)Cn1nnc(N2CCc3cc(OC)c(OC)cc3C2)n1 +O=C(Cc1c[nH]c2cc(F)ccc12)NCC1CN2CCCCC2CO1 +N#Cc1ccc(C=CCNc2cccc(C(=O)NCC(N)=O)c2)cc1 +CC(c1ccco1)N(C(=O)NCc1cnn(C)c1)C1CC1 +CC(Cc1cccs1)NC(=O)c1ccc2c(c1)OCCCO2 +CCOc1ccccc1OCC(=O)Nc1c(C)cccc1C +CCN(C)c1ccc(C(=O)Nc2nccs2)cc1 +CC1CC(C)CN(S(=O)(=O)NC(C)Cc2ccccc2F)C1 +CCc1nnc(NC(=O)c2ccc(-n3cc(C)cn3)cc2)s1 +Cc1cccc(C)c1NC(=O)C(C)Oc1ccc(C#N)cc1 +COCCN1CCN(C(=O)c2ccccc2SC(C)C)CC1=O +C=CCNC(=O)c1cnc2scc(-c3ccc(C)cc3)n2c1=O +Cc1nc2c(s1)CCCC2NC(=O)c1cnc(C(C)(C)C)[nH]c1=O +CN(C(=O)CSc1nc2ccc(Cl)cc2[nH]1)C1CC1 +COC(=O)C(C)(NCC1CC1)c1ccc(S(C)(=O)=O)cc1 +Cc1occc1-c1nnc(SCCC(=O)Nc2ccc(F)cc2)o1 +COc1ccc(-c2nc(COc3ccccc3C(N)=O)no2)cc1 +Cc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)N(C)C)CC2)cc1 +CNC(=O)c1cccc(S(=O)(=O)N(C)c2ccc(C)cc2)c1 +Cc1cccc(C)c1NC(=O)CCn1cnc2sccc2c1=O +O=C(NCCCc1ccccc1)C1CSc2nccc(=O)n2C1 +CNC(=O)c1cc(OC)c(OC)cc1NC(=O)c1ccc(Cl)cc1 +N#CCCn1c(C2CCCCC2)nc2cc3c(cc21)OCCO3 +CCC(C(=O)Nc1ccc(NC(C)=O)cc1)n1c(C)cc(C)nc1=O +CCC(=O)Nc1cccc(NCc2c(C)nn(C)c2C)c1 +CC(C)OC(=O)c1cc(-c2cc(F)ccc2F)on1 +CCCOc1ccccc1-c1cc(CO)c(=O)n(CCC)n1 +O=C1CCC2(CCOC2)CN1CCCN1CCCc2ccccc21 +COCCN1CC2(CCCN(c3ccc(C(C)=O)cn3)C2)CCC1=O +Cc1n[nH]cc1CNC(=O)Cn1c(C)csc1=O +CN(CCc1ccccn1)C(=O)c1ccc2c(c1)NC(=O)CS2 +C=CCN(Cc1ccc(C#N)cc1)C(=O)c1ncoc1-c1ccco1 +CC(Sc1ccccc1Cl)C(=O)Nc1ccnn1C(C)C +COCc1cc(C(=O)N2CCCC2c2noc(C(C)C)n2)c(C)o1 +Cc1ccc(C(=O)C2CCN(C(=O)c3ccoc3)CC2)c(C)c1 +CCn1c(SCC(=O)Nc2cccc(C)c2)nc2c(=O)[nH]cnc21 +O=C(Cc1ccc[nH]1)Nc1ccc2ncccc2c1 +CC(C)CNC(=O)Nc1cccc(Cl)c1-n1cccn1 +CC1CCC2C(C)C(=O)OC3OC4(C)CCC1C32O4 +Cc1cccc(C(=O)N=c2scc(C)n2CC(=O)N2CCCC2)c1 +Cc1cccc(OCCNC(=O)Nc2ccccc2-n2cccn2)c1 +CC(C1CC1)N(C)C(=O)c1cc(F)cc2[nH]cnc12 +CNS(=O)(=O)c1ccc(CCC(=O)N(C)C(C)C)cc1 +CCc1nnc(C(N)c2ccc(F)c(F)c2F)o1 +CNC(=O)C1CCN(c2ccc(Cl)cc2N)CC1 +NC(=O)c1ccc(N2CCC(c3ccc(O)cc3)CC2)nn1 +CCNC(=O)CN1CCN(c2ncnc3c2nnn3CC)CC1 +COCC(O)CN(C)S(=O)(=O)c1cc(Cl)ccc1N +O=C(c1ccc(Cn2cncn2)cc1)N1CCC2(CCCCC2)CC1 +CC(C)(CNC(=O)CCNc1ncccn1)c1ccc2c(c1)OCO2 +N#Cc1cccc(CS(=O)(=O)NCC2CC2)c1 +COc1ccccc1C(O)CNCc1cc(OC)c2c(c1)OCO2 +O=C(Nc1cccc2c1CCCC2)N1CCOCC(CO)C1 +O=C(COc1ccccc1O)N1CCN(c2ccc(O)cc2)CC1 +COc1cc(CN(C)C(=O)c2ccccn2)ccc1SC +NC(=O)c1cccc(OCc2ncc(-c3cccc(F)c3)o2)c1 +COC(=O)C(NCc1cccs1)C1CCOC1 +CC1CN(C(=O)c2ccc(S(=O)C(C)C)cc2)CC(C)O1 +Cn1ncc2c(N3CCC(c4cc5ccccc5[nH]4)CC3)ncnc21 +CC(NC(=O)Nc1nc2ccccc2s1)c1cn[nH]c1 +Cc1ccn2cc(CNC(=O)c3ccc(C(F)(F)F)cc3)nc2c1 +COc1ccc(CCCNC(=O)Nc2ccccn2)cc1 +CC(CNC(=O)NCc1cccnc1)Oc1ccc(Cl)cc1 +N#CCCCn1cccc(OCc2cccc(Cl)c2)c1=O +COc1ccccc1-n1nc(CC(C)C)nc1-c1ccc(C)[nH]c1=O +Cc1cc2nc(C(C)O)n(CC(=O)N3CCCCC3C)c2cc1C +CCc1ccc(OC)c(CS(=O)(=O)c2ccc(N)cc2)c1 +Cc1nn(C)c(C)c1CCC(=O)Nc1cnc2c(cnn2C(C)C)c1 +Cc1cccc(C(=O)NCCC(=O)Nc2nncs2)c1 +CCN(Cc1ccco1)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +O=C(Nc1ccccc1)C1CCN(C(=O)C2CCCC2)CC1 +Cc1ccc(S(=O)(=O)NCC(O)CN2CCOCC2)cc1C +CCC1=C(C(=O)OC(C)C)C(c2ccncc2)NC(=O)N1CC +Cc1cnn(CCc2nc3sc(C)c(C)c3c(=O)[nH]2)c1 +CC(C)(CNC(=O)CCC1CCCO1)c1ccc2c(c1)OCCO2 +CC(C)C(NS(=O)(=O)c1cccc(F)c1)c1nnc2ccccn12 +CCOc1ccccc1OC(=O)Nc1ccc(OC)cc1 +O=C(NCCNC(=O)c1cc2scnc2[nH]1)c1ccsc1 +COCc1ccc(C(=O)N2CCCC(C(N)=O)C2)cc1 +N#Cc1c(C2CCOC2)cc(-c2cc3ccccn3c2)nc1N +Cc1ccc(CN2CC(C(=O)Nc3cccc(Cl)c3)CC2=O)cc1 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1ccc2ccccc2n1 +CC(C)(C)CCOC(=O)c1cc(N)ccc1Cl +Cc1cc(Br)ccc1NC(=O)c1cnc(N)c(Cl)c1 +CCCC(C)C(=O)Nc1ccc(S(N)(=O)=O)c(C)c1 +Oc1cccc(Oc2nnnn2-c2ccccc2)c1 +CC(=O)c1ccc(OS(=O)(=O)c2cccnc2)cc1 +COC(C(=O)NCc1cccc(-c2nc(C)n[nH]2)c1)c1ccccc1 +Cc1nc2ccc(NS(=O)(=O)c3cccs3)cc2s1 +CC(C)Cn1c(SCCC#N)nc2sc3c(c2c1=O)CCC3 +COc1ccc(C(=O)N(C)C2CCc3ccccc32)cc1OC(F)F +Cc1csc(N2CCN(c3cnc4ccccc4n3)CC2)n1 +Cc1ncsc1C(=O)Nc1nnc2ccccn12 +N#Cc1c(-c2ccc(Cl)cc2)cc(C2CC2)nc1SCC(N)=O +CCN(CC(=O)NC(C)(C)C)C(=O)CNC(=O)c1ccc(C)s1 +O=C(N1CC(c2ccccn2)C1)C12CC3CC(CC(C3)C1)C2 +CC(C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C)c1cccs1 +Cc1nc(COc2cccc(C(=O)NCc3cscn3)c2)cs1 +Cc1nc2sc(C3CC3)c(Br)c2c(=O)[nH]1 +COc1cc(OC)cc(C(=O)N(Cc2ccccc2F)C2CC2)c1 +O=C(NCCNc1ncccn1)c1cc(Cl)ccc1F +CCOc1ccccc1C(=O)NC(C(N)=O)C(C)CC +CCOc1cc(N)cnc1N(CC)c1ccccc1 +CCc1nnc(NC(=O)C2Cc3ccccc3CN2C(C)=O)s1 +O=C(Nc1nnc(C2CC2)s1)N1CCC(c2ccccc2)CC1 +CCCc1cc(NC(=O)C2CCN(c3cnccn3)CC2)n[nH]1 +Cc1ccc(O)c(C(=O)NCc2ccc(CN3CCOCC3)cc2)c1 +COc1ccc(-c2nonc2NC(=O)c2cccs2)c(C)c1 +Cc1ccnc(SCC(=O)NC2CCCC2)n1 +Cc1ccc(C2CN(C(=O)Nc3ccc4c(c3)COC4)CCO2)o1 +CN1CCc2c(sc3ncn4nc(C5=CCCC=C5O)nc4c23)C1 +CC1CCc2nc(N)c(C(=O)NC3CCCC3)cc2C1 +O=C(CCOc1ccccc1Cl)NC1CCCCC1O +CCOc1ccccc1CN(C)C(=O)c1cnc(C2CCCO2)s1 +Nc1ccc(OCCN2CCOCC2)c(Cl)c1 +COc1cc(C(=O)N2CCOCC2C)ccc1OCc1cscn1 +Cc1noc(CCC(=O)N(Cc2ccco2)Cc2cccs2)n1 +Cc1nc(-c2ccsc2)sc1C(=O)NC(C)C1CC1 +CCN(CCC#N)S(=O)(=O)c1cc(Cl)ccc1C +CC(C)C(=O)Nc1nnc(S(=O)(=O)NCc2cccnc2)s1 +CCC(C)NC(=O)Cc1ccc(N2CCCC2=O)cc1 +COc1ccc2c(=O)c(C(=O)NCCc3ncc(C)s3)c[nH]c2c1 +CC(C)OC(=O)CCC(=O)Nc1ccc(Cl)cc1Cl +O=S(=O)(c1cc(F)ccc1F)N1CCC2(CC1)OCCO2 +O=C(NC12CC3CC(CC(C3)C1)C2)c1ccncc1F +CN(C(=O)c1ccc(S(=O)(=O)N(C)C)cc1)C1CC1 +CC(=O)c1ccc(NC(=O)COC(=O)Cc2ccc(C)cc2)cc1 +Cn1cccc1CN(C(=O)c1ccccc1Cl)C1CC1 +N#Cc1ccccc1N1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1ncsc1C(=O)Nc1cc(C(C)C)n[nH]1 +CC(C)(O)CN1CCN(C(=O)c2ccc(-c3ccc(F)cc3)o2)CC1 +COc1ccccc1-c1nc(-c2ccc(C)nc2OC)no1 +O=C(c1cncn1-c1ccccc1)N1CCN(c2ccc(O)cc2)CC1 +NC(=O)c1nn(Cc2ccncc2)c2c1C(=O)CCC2 +Cn1ccc(CNC(=O)c2cc3ncc(Br)cn3n2)n1 +CCCCn1c(N)c(C(=O)OC)c2nc3ccccc3nc21 +CC(NC(=O)c1cccs1)(C(N)=O)c1cccc(Cl)c1 +CN(C)c1ncncc1N1CCC(C(=O)NC2CCCCCC2)CC1 +COC(=O)CC(c1cc(Cl)ccc1OC)C1CC1 +Cc1cccc(CCNC(=O)c2cccnc2N)c1 +CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)Nc1ccncc1 +O=C(CCSc1ccccc1F)NCc1nc2ccccc2[nH]1 +Oc1cc(-n2ccc(-c3cnccn3)n2)cc(F)c1F +CC(=O)Nc1cccc(NCc2ccccc2C)c1 +CC(C)(C)C(=O)Nc1ccc(NC(=O)C2CCC2)cc1 +COc1ccc(C(=O)OC2CCOCC2)c(F)c1 +CC(C)Oc1ccc(C(=O)N2CCC(=O)CC2)cc1Cl +O=C(c1ccc(-n2ccnn2)cc1)N1CCCc2cc(F)cc(F)c21 +Cn1cc(-c2nc(CNc3cc(Cl)ccc3C(N)=O)cs2)cn1 +Nc1cc(=O)[nH]c(SCCCOc2ccc(F)cc2)n1 +O=C(CCN1CCCc2ccccc21)N1CCNCC1 +COc1ccc(CNC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)cc1 +COc1cccc(C2CCCN2C(=O)c2cccc(C)n2)c1 +O=C(Cn1c(CNC(=O)C2CC2)nc2ccccc21)c1ccccc1 +COCc1c(C(=O)NC2CCCCC2)nnn1-c1cccc(C)c1 +Cc1nc(-c2nnc(NC(=O)CCc3ccccc3)o2)cs1 +CC(C)c1ccc(C(=O)N2CCCC(CN3CCOCC3)C2)cc1 +O=C(CCn1c(=O)oc2cc(Cl)ccc21)N1CCCCCC1 +COC(=O)c1ccc2c(c1)CCN2C(=O)C1CCOCC1 +Cc1c(NC(=O)c2ccsc2)cccc1S(N)(=O)=O +O=C1CCCN1c1ccc(-c2csc(N3CCCC3)n2)cc1 +Cc1nnc2n1CCN(CC(=O)N1CCc3ccccc3C1)C2 +COC(=O)C(C)CNC(=O)Nc1cccc2[nH]ccc12 +Cc1cn2c(CC(=O)Nc3ccccc3F)csc2n1 +Cc1cccc(CNC(=O)NCCCOc2ccc(Cl)cc2C)n1 +CNS(=O)(=O)NCC(C)NS(=O)(=O)NC +COC(=O)c1cc(-c2cccc(Br)c2)on1 +Cc1ccc(CNC(=O)N(C)CC2CC2)c(N(C)C)c1 +Cc1ccc(CNC(=O)NCCNC(=O)c2cccnc2)cc1F +Cc1noc(C)c1CCCNC(=O)NCC(=O)NC1CCCCC1 +Cc1cnc(NC(=O)c2ccc(COc3ccc(F)cc3)o2)s1 +CCOc1ccccc1NC(=O)Nc1nnc(-c2ccco2)o1 +Cc1nc(C(N)c2ccc3[nH]ccc3c2)sc1C +Oc1cc(-c2cccnc2)cc2c1OCCN(Cc1cccs1)C2 +Cc1cc(C(=O)Nc2cnn(C)c2)nc(N2CCOCC2)n1 +O=C(c1ccsc1)N1CCCn2nnc(COCC3CC3)c2C1 +CCNc1ccc(Cl)cc1C(=O)NCC(F)(F)F +O=C(Cn1cnc2ccccc2c1=O)NCC1Cc2ccccc2O1 +CCN1CC2(CCCCN2C(=O)c2ccn(C)n2)CC1=O +COc1ccc(CNC(=O)C2CC=CCC2)c(OC)c1OC +Cc1ccc(NC(=O)c2cn(C)nc2C(C)(C)C)cc1C(=O)N(C)C +Cc1nc(-c2ccccc2)sc1C(=O)NC(C)(C)C(N)=O +CC(C)Oc1ccc(C(=O)Nc2ccc3c(c2)COC3)cn1 +Cc1cc(C)n2nc(CCCOC(=O)c3ccc(C)s3)nc2n1 +Cc1ccc(Nc2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1C +Cc1cc(C(=O)NCCNC(=O)c2ccc(F)cc2)nn1C +NC(=O)N1CCc2cc(NC(=O)c3scnc3C3CC3)ccc21 +COc1ccc(Cl)cc1-n1nc(C2CC2)nc1C(C)n1cncn1 +Cc1ccc(-c2ncco2)cc1NC(=O)NCCC(=O)N(C)C +COc1ccccc1-c1c(C#N)nnn1CC(O)CO +COc1ccc(Nc2ccc(C#N)cn2)cc1OC +COc1ccc(OC)c(NC(=O)Nc2cc(C)ccn2)c1 +Cn1ncc2c(N3CCOCC3)nc(NCCc3ccccc3)nc21 +O=C(CCNC(=O)c1ccccc1)Nc1ccc(F)c(Cl)c1 +Cc1nnc(SCc2c(Cl)cccc2Cl)n(N)c1=O +c1cc(-c2nc(-c3ccncc3)no2)c2[nH]ncc2c1 +CCOC(=O)CCCNC(=O)Nc1ccc(Br)cc1 +CC(C)C1Oc2ccc(N)nc2N(CCCC(N)=O)C1=O +CCC(NC(=O)CCc1c(C)noc1C)c1cccs1 +COc1ccc(COC(=O)c2ccc(-n3cncn3)nc2)cc1 +O=C1CC(c2ccccc2)C2(CCN(C(=O)C3CC=CC3)CC2)N1 +CCCCc1nnc(NC(=O)C(C)NC(=O)c2ccco2)s1 +COc1ccc(C2CCCN2c2cc(C)nc3ncnn23)cc1 +O=C(Nc1ccccc1-n1cncn1)c1cc(Cl)c2c(c1)OCO2 +COc1ccccc1C(=O)Nc1cnn(CC(F)F)c1 +Cc1sc2ncn(CC(=O)N3CCOCC3C)c(=O)c2c1C +N#Cc1cccc(NC(=O)CS(=O)(=O)c2nc3ccccc3[nH]2)c1 +CC(=O)N1CCCC1C(=O)c1ccc2c(c1)OCO2 +CN(Cc1nc(-c2cccnc2)no1)Cc1c(F)cccc1Cl +O=C(NCc1nncn1C1CC1)Nc1ccc(F)cc1C(F)(F)F +Cc1ccccc1C(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +O=C(Cn1nc(-c2ccco2)oc1=O)c1ccc2c(c1)CCCC2 +c1ccc(CCC2CN(CCCn3cccn3)CCO2)cc1 +CC(C)CN(CC(C)C)c1cnn(-c2ccccc2)c(=O)c1N +Nc1cccc2c1nc(-c1cccc(Cl)c1)n2CCCO +Cc1cc(C)c(C(=O)NCCCCc2ccccn2)c(=O)[nH]1 +Cc1nc(-c2cccc(NC(=O)NCCC3CCCCO3)c2)no1 +CCOC(=O)c1cc(NC(=O)N(C(C)C)C(C)C)c(C)nc1C +CCc1nc2n(n1)CC(Nc1ccnc(-c3ccccc3)n1)CC2 +O=C(CCc1ccc2c(c1)OCO2)Nc1ccc(-n2cncn2)nc1 +O=S(=O)(c1ccccc1F)N(Cc1cccnc1)C1CC1 +O=C(OCc1ccccc1)c1cccc(N2CCCS2(=O)=O)c1 +COC(=O)c1sccc1S(=O)(=O)N(CCO)C1CC1 +CCNC(=O)C1CCN(C(=O)N2CC(CC)Oc3ccccc32)CC1 +O=C(Cc1csc(N2CCCC2=O)n1)NC1CCCCC1 +CCCc1nnc(N2CCC(N3CCCC3=O)CC2)o1 +Cc1cc(CN(C)C(=O)c2ccc(C)c(F)c2)no1 +COC(=O)N1CCC(NC(=O)Nc2nc(C3CC3)cs2)CC1 +O=C(Nc1nccs1)C(Cc1ccccc1)NC(=O)N1CCCC1 +Cc1nc(C2CN(C(=O)Cc3ccc4ccccc4c3)CCO2)no1 +Cc1ccc(NC(=O)c2cc(F)ccc2C)c(N)c1 +Cn1c(C(C)(C)C)c(N)c(=O)n1-c1ccc(Br)cc1 +Cc1nc2sccn2c(=O)c1NC(=O)CCC1CCCC1 +O=C(C1CCC(=O)N(C2CC2)C1)N1CCN(C2CCCC2)C(=O)C1 +Nc1c(NC2CCCC2)ncnc1N1CCN(c2ccccc2)CC1 +CCCCNC(=O)C1CCCN(c2nnc3cccc(C)n23)C1 +COc1ccc(NC(=O)c2ccn3cncc3c2)cn1 +CC(=O)N1CCC(NC(=O)Cn2nnc3ccccc3c2=O)CC1 +C=C(C)CN(CC)C(=O)Cc1cn2ccccc2n1 +Cn1c(SCc2ccc(Br)cc2F)nnc1C1CC1 +Cc1ccc(C)c(S(=O)(=O)c2c(C)cc(C)[nH]c2=O)c1 +N#Cc1cccc(S(=O)(=O)NCc2ccc(F)cc2)c1 +O=C(c1cnn(-c2ccccc2)n1)N(Cc1ccccc1F)C1CC1 +CC(NCC(C)(O)c1cccs1)c1cccc(N2CCCC2=O)c1 +CC(=O)c1ccc(C)n(Cc2cccc(Cl)c2)c1=O +Nc1cc(Cl)cc2c1OC(c1ccc(F)cc1)CC2=O +COc1ccc(-c2nccn2CC(N)=O)c2ccccc12 +CCCCCN(C)S(=O)(=O)c1cn(C)nc1N +CCOC(=O)C1CCN(c2nc(OC)nc(OC)n2)CC1 +Cc1ccc(CNC(=O)Nc2cccc(C(=O)NC3CC3)c2)c(C)c1 +CC(C)CC(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +O=C(NCCO)c1cc2occc2n1Cc1cccc(F)c1 +CCN(CCO)C(=O)C1CCCN(S(=O)(=O)c2cccs2)C1 +COc1ccc(-c2cnnc(NCCN3CCCCC3=O)n2)cc1F +Cc1ccc(C(=O)Nc2nc3c(s2)C(=O)CC(C)(C)C3)c(C)n1 +CC(C)Cc1nnc(NC(=O)NCc2ncc[nH]2)s1 +Nc1nccnc1C(=O)OCC(=O)NCc1ccc(F)cc1 +Cn1cc(C(=O)N2CCCC3(CCN(c4ccccc4)C3=O)C2)cn1 +COc1ccc(Cl)c(NC(=O)NCc2cnn(C)c2)c1 +Cc1cc(CN(C)C(=O)Nc2ccc3c(c2)OCC(=O)N3)no1 +Cc1cccc(CNC(=O)CNC(=O)c2cc(C)nn2C)c1 +Cc1nc(-c2cccc(OCc3nccn3C(F)F)c2)no1 +Cc1cc(C)n2nc(C(=O)Nc3ccc(C(C)C)cc3)nc2n1 +Clc1cccc2ncn3nc(-c4ccco4)nc3c12 +O=S(=O)(Cc1cccc(Cl)c1)N(Cc1ccsc1)C1CC1 +COc1ccc(C(=O)N(C)CC(O)C2CC2)c(O)c1 +Cc1ccc(C)c(CNC(=O)c2cnc3sccn3c2=O)c1 +CCCC(=O)NCC(=O)NCc1c(C)cc(C)cc1C +CCCCN(C)S(=O)(=O)N1CCCC1Cc1cccc(F)c1 +O=C(COc1ncnc2sc3c(c12)CCCC3)NC1CCCC1 +CC1CCCCN1C(=O)C(C)n1nc(-c2ccccc2)ccc1=O +COCCn1cc(NC(=O)NCC2(C(=O)N(C)C)CCCC2)cn1 +COc1coc(C(=O)Nc2cnc3n2CCCC3)cc1=O +N#Cc1ccc(C(=O)NCCn2nc(-n3cccn3)ccc2=O)cc1 +Cc1cc(OCc2cc(F)ccc2F)nc(-c2cnccn2)n1 +CCn1c(NC(=O)c2ccc(C)s2)nc2ccccc21 +Cc1ccc(F)c(NC(=O)N2CCN(c3nccs3)CC2)c1 +Cc1cc(C)n(-c2nc3c(c(=O)n(CCC(C)C)c(=O)n3C)n2C)n1 +CC(c1ccccc1)n1c(=O)[nH]c2ccsc2c1=O +CCOc1ccccc1NC(=O)c1c(Br)cnn1C +OC(COc1ccccc1)Cn1ccnc1-c1cnccn1 +CCOC(C)C(=O)Nc1ccc(OCC(F)(F)F)c(C)c1 +CCn1cc(NC(=O)C(C)(C)NC(=O)NC)ccc1=O +COc1cc(C)ccc1OCC(=O)NC(C)C(C)C +Nc1ccc(O)c(-c2n[nH]c(-c3ccccc3)n2)c1 +CC(C)(C)OC(=O)N1CCc2cc(Cl)c(N)cc21 +CC(=O)OC(c1ccccc1)C1NCCc2ccc(F)cc21 +CCOC(=O)c1sc(NCC2CCCO2)nc1C +CC(O)CNC(=O)CNC(=O)NCc1ccc(F)cc1 +CN(C)C(=O)c1ccc(C(=O)N2CCCCCC2)cc1 +O=C(NCC1(c2ccc(F)cc2)CC1)c1cnc(C2CCCO2)s1 +Cc1nc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2[nH]1 +CC(=O)N1CCc2cc(NC(=O)N3CCCC3C3CCCC3)ccc21 +Cc1noc(C)c1CN1CCN(C(=O)NCc2ccccc2)CC1 +O=C(NCC1(c2ccccc2)CC1)c1c[nH]c(C(=O)N2CCCC2)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)CN(C)C(=O)OC(C)(C)C +Cc1cc(C(=O)Nc2ccc(CC(N)=O)cc2)c(C)s1 +Nc1cc(-c2nncn2-c2ccccc2)ccc1F +Cc1cccc(-c2nc3nc(C)cc(N4CCOCC4)n3n2)c1 +CC(C)(Oc1ccc(C#N)cc1)C(=O)Nc1ccccc1 +Cc1ncsc1CCC(=O)N1Cc2cnc(CC(C)C)nc2C1 +COCCN(Cc1cccnc1)C(=O)c1c[nH]nc1C1CCCCC1 +COc1cccc(C(=O)Nc2ccc(C(C)=O)cc2)c1 +O=C(Cc1cccc(F)c1)Nc1ccc(N2CCCC2)cn1 +COc1ccc(Br)c(CNC(=O)C(C)OCC(C)C)c1 +CCCCN(C)S(=O)(=O)c1cnc(NC)c(Cl)c1 +CNS(=O)(=O)c1ccc(NC(=O)c2cc(Cl)ccn2)cc1 +O=C(c1cncc(N2CC3CC=CCC3C2)n1)N1CCOCC1 +COC(C(=O)Nc1ccc2c(c1)NC(=O)C(C)O2)c1ccccc1 +COc1ccc(C=c2sc3nc4ccccc4n3c2=O)cc1OC +CC(C)C(=O)Nc1ccc(C(=O)NCc2ccncc2)cc1 +Cc1ncc(-c2nc3c(s2)CC(CO)CC3)o1 +CC(C)(C)CCC(=O)N1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +C=CCNC(=O)C(C)Nc1cccc(N2CCOC2=O)c1 +CCNS(=O)(=O)c1ccc(OC)c(-c2noc(C)n2)c1 +O=C(c1cccc2[nH]ccc12)N1CCN(c2cccc(Cl)c2)CC1 +NC(=O)CSc1nnc(COc2ccc(Cl)cc2)o1 +COC(=O)CCNC(=O)CNC(=O)c1ccc(C)c(C)c1 +N#Cc1ccc(OCC(=O)Nc2ccccc2N)cc1 +Cc1cc(NC(=O)N(Cc2ccc(F)cc2)C2CC2)no1 +Cc1cc(C(=O)N2CCN(c3nc4c(C)cccc4s3)CC2)no1 +Cc1ccnc2nc(C(=O)Nc3cnn(CC4CC4)c3)nn12 +NS(=O)(=O)CCNc1ncnc2c1cnn2-c1ccc(F)cc1 +CCc1nnc2n1CC(NC(=O)c1cc(=O)[nH]c3ccccc13)CC2 +Cc1ccc(-c2ncco2)cc1NC(=O)N(C)C(C)CC#N +O=C(NCc1nnc2n1CCCCC2)c1cc(=O)[nH]c2ccccc12 +CCN1CC(C(=O)N(CC)Cc2cccc(Cl)c2)CC1=O +COc1ccc(NC(C)c2ccccc2OC)cn1 +Nc1c[nH]c(C(=O)Nc2ccccc2OC(F)F)c1 +COc1ccc(NC(=O)CCC(=O)c2ccc(F)cc2F)c(OC)c1 +Cc1nc(-c2ccsc2)ccc1C(=O)N1CCOCC1(C)C +CN(C)Cc1cc(=O)c(O)cn1CCc1ccccc1 +CCc1nnc(CNc2cc(C3CC3)ncn2)s1 +C=CCNC(=O)N1CCN(CC(=O)N2CCCCC2C)CC1 +O=C(NCCN1CCOCC1)c1cc2c(=O)c3ccccc3oc2o1 +COCCn1c(=O)n(CC(=O)NC2CC2)c2cccnc21 +COc1ccccc1S(=O)(=O)NC1CC2C(=O)NCC(=O)N2C1 +Cc1cc(C(=O)NC2CCN(C(=O)c3cccnc3)CC2)no1 +O=C(NCCCc1nc(-c2ccncc2)cs1)Nc1ccccn1 +Cc1cc(=O)[nH]c(-c2ccc(NC(=O)c3cc(F)ccc3C)cc2)n1 +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccncc1F +CCN(Cc1ccccc1NC(=O)NCCOC)C(C)=O +CC(C)CCc1cc(=O)[nH]c(N2CCN(C(=O)c3ccco3)CC2)n1 +CCOc1cc(S(=O)(=O)N2CCN(C(C)=O)CC2)c(C)cc1C +c1ccc2sc(-c3csc(N4CCOCC4)n3)nc2c1 +Cc1cn2cc(NC(=O)c3nc(C)n(-c4ccccc4)n3)ccc2n1 +Cc1ccc(C(=O)NCc2nnc3n2CCCCC3)cc1F +O=C1N2CN(CCCO)CN3C(=O)N4CN(CCCO)CN1C4C23 +O=C(NCc1cccc(F)c1)NC1CCSc2c(F)cccc21 +COc1cc2c(=O)ccn(CCC#N)c2cc1OC +CCc1nn(-c2ccccc2C(=O)OC)c2c1CN(C)CC2 +CC(NC(=O)Nc1ccc(F)cc1F)c1nc[nH]n1 +COCCNC(=O)NCCc1ccccc1Cl +COC(=O)c1c(-c2ccc(Cl)cc2)noc1N +COc1c(CN2CCC(N3CCOC(C)C3)CC2)c(C)nn1C +O=C(NCC(O)CO)c1ccc2nc(-c3ccccc3)cn2c1 +Cc1cccc(NC(=O)CCc2ccc(S(N)(=O)=O)cc2)n1 +CCn1cc(NC(=O)N2CCC(C(=O)Nc3nccs3)CC2)cn1 +COc1ccc(CNC(=O)C2CC3CCC2O3)cc1 +COC(=O)CC1CN(Cc2cccc(OC(F)(F)F)c2)CCO1 +CCOC(=O)c1cc(-c2cc(C)ccc2OCC)nn1C +CCC(=O)c1ccc2c(c1)N(CC(=O)NCCOC)C(=O)CO2 +CC1(NC(=O)NCc2ccnc(OC(C)(C)C)c2)CCOC1 +Cc1c(NC(C)C(C)C)cccc1C(=O)N1CCCN(C(N)=O)CC1 +CC(C)C(=O)N1CCCC1C(=O)NCc1ccnc(OC(C)(C)C)c1 +CCCC(=O)NCC(=O)Nc1ccc(C(=O)N(C)C)c(C)c1 +Cn1nccc1CNC(C(N)=O)c1ccc(F)cc1 +CCCNC(=O)CCNC(=O)c1cnc(-c2cnn(C)c2)s1 +Cc1ccc(C(=O)N2CCCC2c2ccncc2)cc1S(C)(=O)=O +COc1ccccc1OCC(=O)NCC#CCOc1ccc(C)nc1 +Cc1ccc(CC(=O)N2CCCCC2C2OCCO2)cc1 +O=C(COC1CCCC1)NCCc1nc2ccccc2n1C(F)F +CCC(C)c1ccc(S(=O)(=O)N(CC)CCO)cc1 +O=C(Oc1cccc(Cl)c1)c1sccc1-n1cnnn1 +Cc1nn(C)c2nc(-c3ccco3)cc(C(F)(F)F)c12 +Cc1cc(S(=O)(=O)N(C)c2ccccc2C(N)=O)c(C)o1 +CCC1C(=O)Nc2c(Cl)cc(C(O)C(C)C)cc21 +CC(=O)NC(CC(=O)Nc1nc(C)no1)c1ccc(Cl)cc1 +CC(=O)N1Cc2ccccc2CC1C(=O)NC(C)CN1CCOCC1 +CCNC(=O)C1(NC(=O)CCc2c(C)noc2C)CCCCC1 +CC(Sc1nnnn1C(C)(C)C)C(=O)N(C)CCC#N +Clc1ccc(-c2nc(-c3cccnc3)n[nH]2)cc1 +COc1cccc(N(C(C)C(=O)N2CCCC2)S(C)(=O)=O)c1 +CCOc1ccc(CCC(=O)N2CCN(CC(C)(C)O)CC2)cc1 +CCC1Oc2ccc(N)cc2N=C1Nc1cccc(C#N)c1 +CC(C)COC(=O)CN1CCNc2cc(Cl)ccc21 +COC(=O)c1csc(NCc2cccs2)n1 +Cc1ccc(S(=O)(=O)N(C)C2(C#N)CCCC2)cc1 +Cc1nnc2n1C1CN(C(=O)C3CCCC3)CC1CC2 +O=C(Nc1cccc(-c2nc3ccccc3o2)c1)c1cccnc1 +Cc1cc(C(=O)CCC(=O)Nc2ccn(C)n2)c(C)s1 +Cc1ccccc1CNC(=O)Cc1c(C)nc2nc(N)nn2c1C +CC1CN(C2CCN(C(=O)c3ccsc3)CC2)CC(C)O1 +Cc1cc(C(=O)NC(c2nnc3ccccn23)C(C)C)ccc1F +Cc1ccc(NC(=O)c2ccc(C)nc2)c(OCC(=O)N(C)C)c1 +CC(C)C(=O)N1CCC(NC2CCN(CC(F)(F)F)C2=O)C(C)C1 +CC(c1ccc(S(N)(=O)=O)cc1)N(C)C(=O)NCC1CCCO1 +Cc1cc(CN(C)C(=O)Nc2ccc(F)c(C(F)(F)F)c2)no1 +CCC(C)C(=O)Nc1nnc(-c2ccccn2)s1 +O=C(Cn1nnc2ccccc21)N1CCN(C2CCCC2O)CC1 +CCCS(=O)(=O)NCCN1c2ccccc2CC1C +COCCNC(=O)NCCNC(=O)c1ccccc1 +O=C(CCC(=O)c1ccc2c(c1)CCCC2)Nc1nccs1 +Cc1sc2ncc(C(=O)NCCc3ccccn3)c(=O)n2c1C +Cc1ccc(C(=O)Nc2ncn(Cc3ccccn3)n2)cc1 +CNC(=O)C1CN(C(=O)c2coc(C)n2)CCN1C +Cc1cnc(C(=O)N(Cc2ccccc2)C(C)C2CC2)cn1 +CC(C(N)=O)N(c1ccc(Cl)cc1)S(C)(=O)=O +Cc1[nH]nc(-c2ccc(SC3CCCC3)cc2)c1N +CCC(=O)N1CCCC1c1nnc(-c2ccsc2)o1 +Cc1ccc(OCC(=O)Nc2cc(N)ccc2F)cc1 +CCC(C)OCCC(=O)Nc1cc(Cl)ccc1N +CCOC(=O)C(C)(C)NC(=O)c1ccc2c(c1)OCO2 +Cc1ccc2c(CC(=O)N(CC(N)=O)C(C)C)coc2c1 +Cc1cnc(C(=O)NCCOCc2ccccc2)cn1 +CCOC(=O)c1nnc(Cc2ccc(F)cc2Cl)o1 +CN(Cc1ccsc1)C(=O)c1ccccc1-c1ncc[nH]1 +COC(C)(C)CC(C)NC(=O)NCCc1ccc(F)cc1C +CC(C)COc1ncc(CNC(=O)N2CCOCC2C)cc1Cl +Cc1nc2c(cc(Oc3ccc4nnnn4n3)c3ccsc32)s1 +O=C(CCc1ccc(F)c(F)c1)Nc1cccc2cn[nH]c12 +CC(C)N(CCCNC(=O)c1n[nH]c2ccccc12)S(C)(=O)=O +Nc1cc(C(F)(F)F)ccc1N1CCN(C(=O)C2CC2)CC1 +Cc1cc2c(cc1O)C(c1cncc(F)c1)NCC2 +CCC(=O)N(C)CC1CCC(c2cc(CN(C)C(C)=O)n(C)n2)CC1 +Cn1nccc1CNC(=O)NCC(O)COc1ccc(F)cc1 +Cc1ccc(-c2nc(C(=O)Nc3ccc(F)c(C#N)c3)cs2)o1 +CC(Oc1ccc(Cl)cc1Cl)C(=O)N(C)Cc1cnn(C)c1 +CCN(CCC#N)C(=O)c1cccc(OC(F)F)c1 +COc1ccc(-n2nnc(C(=O)N3CC(O)C3)n2)cc1 +COc1ccccc1CC1CCCN1c1cc(-n2ccnc2)ncn1 +CCc1noc(-c2ccc(SCC(=O)Nc3ccccc3)nc2)n1 +Cc1cc(NC(=O)C(C)OCc2ccccc2)c2ncccc2c1 +CCN(CC)S(=O)(=O)c1cccc(C(=O)NC2CCCC2)c1 +COc1cnc(NC(=O)c2ccc(Cl)cc2)s1 +O=C(NC1CCOC2(CCN(Cc3cccs3)C2)C1)c1ccco1 +COc1cc2c(c(OC)c1O)C(c1ncccn1)NCC2 +CC(=O)NCC(=O)NC1(c2nc(C(C)(C)C)no2)CCCCC1 +CN(C)c1c(Cl)cccc1NC(=O)c1ccnc(F)c1 +CCS(=O)(=O)N1CCC(C(=O)N(C)c2ccc(C)cc2C)CC1 +COc1ccc(NC(=O)CSc2nc3ccncc3[nH]2)cc1 +CCOc1ccc(NC(=O)N(C)Cc2ccccn2)cc1 +CC(C)Cn1ncc(C(=O)NC(C)CO)c1C1CC1 +Cc1noc(C)c1NC(=O)Nc1nc(C(F)(F)F)cs1 +CCN(C(=O)Cn1c(C(C)(C)O)nc2ccccc21)c1ccccc1 +CCCNC(=O)CN1C(=O)C(CC)(CC)Oc2ccc(O)cc21 +CC(=O)Nc1cccc(-n2cnnc2SCc2cccnc2)c1 +O=C(Nc1nccs1)C1CCCN1C(=O)c1ccn2ccsc12 +CC(=O)N1CCc2ccc(NS(C)(=O)=O)cc21 +COc1ccc(C(=O)NCC(=O)N(C)C)cc1Br +CCc1cccc(C)c1NC(=O)Cn1c(=O)oc2cc(Cl)ccc21 +NS(=O)(=O)c1ccc(-c2nc(-c3ccncc3)no2)o1 +O=C(c1c[nH]nc1C1CCCCC1)N1CCCC1c1ccccn1 +Cc1cccc(-n2nc(C)nc2C(Cc2cnc[nH]2)n2cccc2)c1 +Nc1ccccc1S(=O)(=O)Nc1ccc(Cl)cn1 +CCn1c(SCC(=O)c2ccccc2)nnc1N1CCOCC1 +COc1ccccc1-c1nc2cc(C(C)=O)ccc2n1C +CC(=O)N1CCN(C(=O)c2cccc3nscc23)CC1 +CC(=O)N1CC(C(=O)N2CCN(c3cccc(Cl)c3)CC2)C1 +CC(=O)N1CCC(C(=O)NCc2cnn(C)c2)CC1 +CC(C)(C)NC(=O)N1CCC(NC(=O)c2cc3ccccn3c2)CC1 +COc1ccccc1CNC(=O)COc1nc(C(C)(C)C)no1 +COC(=O)c1cc2n(n1)CCN(C(=O)c1sccc1NC(C)=O)C2 +O=C(Cn1[nH]c(=O)ccc1=O)Nc1cccc(C(F)(F)F)c1 +CC(NC(=O)CCn1c(=O)oc2ccccc21)C1CCCCC1 +COc1cc(OC)c(NC(=O)CSc2ccncc2)cc1F +CC1Oc2ccc(C(=O)N3CCC(=O)CC3)cc2NC1=O +Cc1ccc(N(CCC#N)C(=O)CSc2ncn[nH]2)cc1C +COc1ccc(C2CCN(C(=O)c3ccccn3)CC2)cc1 +CC(C)N(Cc1ccccc1)C(=O)CCc1ccco1 +Fc1ccc(-c2noc3ncnc(NCCN4CCOCC4)c23)cc1 +C=CCn1c(=O)oc2ccc(C(=O)Nc3nccs3)cc21 +CCOC(=O)c1csc(NC(=O)c2cccs2)n1 +FC(F)C(F)(F)CN1CCN(CC2=CCCOC2)CC1 +CCCC1CN(C(=O)c2cccc(Cl)c2Cl)CCO1 +CCCNC(=O)c1nn(-c2ccccc2)c2ccccc2c1=O +COc1cc(C2NCCc3c(N)cc(F)cc32)ccc1C +CCCOC(=O)NCc1cc2n(n1)CCCN(S(C)(=O)=O)C2 +COc1ccccc1CCNC(=O)COc1cccc(F)c1 +CC(=O)Nc1ccc(NC(=O)C2(c3ccccc3)CCCC2)cc1 +O=C1CC(c2ccccc2)c2c(c3ccccc3[nH]c2=O)O1 +COc1ccnc(NC(=O)c2cccc(NC(=O)C3CC3)c2)c1 +CC(C)NC(=O)N1CCCN(CC(F)(F)F)CC1 +Cc1ccc(CNS(=O)(=O)c2ccc(F)cc2F)cc1 +CC(NC(=O)CCn1cccn1)c1nnc2n1CCCCC2 +CCCCn1nnnc1NC(=O)NCc1nc(C)c2c(n1)CCCC2 +CCN(C(C)=O)c1cc(OC)c(OC)cc1Br +c1ccc(CSc2nc(CCC3CCCC3)n[nH]2)nc1 +O=C(NCc1cccs1)c1cc(-c2cccc(O)c2)on1 +COc1ccc(C(=O)Nc2cc(CC(C)C)nn2C)cc1 +CCc1noc(CC)c1CC(=O)Nc1ccc2oc(=O)[nH]c2c1 +CC(O)CN(C)C(=O)c1ccc2c(c1)NC(=O)CO2 +CCC(c1nc(CC(N)=O)nn1Cc1ccc(C)cc1)n1cccn1 +CC(O)CN(Cc1ccc(C(=O)N2CCCC2)cc1)c1ccccc1 +CC(=O)c1cnn(-c2ccc(Cl)cc2Cl)c1C +CN(C(=O)CCCC(=O)c1ccc(F)cc1)c1nccs1 +Cc1[nH]c2ccccc2c1C(=O)NCCc1ccc2c(c1)OCCO2 +NC(=O)CN1C(=O)N2CCN=C2c2cnn(-c3ccc(Cl)cc3)c21 +O=C(c1c(F)cccc1F)N1CCC(OCc2ccccc2F)CC1 +CC(NC(=O)c1cscn1)C(=O)Nc1cccc(N2CCCC2)c1 +COc1ccc(-c2csc(NC(=O)c3ccsc3)n2)cc1F +COc1ccc(OC)c(CC(=O)N(C)Cc2ccc(C)o2)c1 +O=C(CSc1ccc(-c2cccnc2)nn1)NCC1CCCO1 +CCN(Cc1ccccc1)C(=O)c1ccc2c(n1)NC(=O)CC2 +CC(NC(=O)CN1CCOc2ccccc21)c1ccccc1 +CCc1ccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3CC)cc1 +CC(C)c1ccc(O)c(NC(=O)c2cccnc2)c1 +O=C(c1ccnc(OC2CCC2)c1)N1CCCC1C1CCCC1 +N#Cc1ccc(NC(=O)CCCNC(=O)c2cccs2)cc1 +CC(C)C(NC(=O)c1cccs1)C(=O)Nc1nccs1 +c1ccc(CCNCc2ncc(-c3ccco3)s2)cc1 +CCCn1nc(C(=O)Nc2cccc(C(N)=O)c2)ccc1=O +C=CCNC(=O)c1ccc(NC(=O)C2CC(=O)N(C)C2)cc1 +Cc1nn(CC(=O)N2CCc3ccccc3C2)c(C)c1Cl +CCCN(CC1CC1)S(=O)(=O)c1cc(Br)cnc1N +CCCn1ncc(-c2ccc(OC)c(F)c2)c(C#N)c1=O +COC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)CC(=O)N(C)C)c1 +CCCNS(=O)(=O)c1c(C)[nH]c(-c2nnc(C3CCC3)o2)c1C +Cc1nn(-c2ccc(C(=O)NC3CC3)cc2)c2c1C(=O)CC(C)(C)C2 +CC(C)C(=O)N(c1cccc(O)c1)S(C)(=O)=O +Cc1nc(SCC(=O)NC2CCCCC2)n(C2CC2)c1C +COc1ccc(C(O)C(C)NC(=O)CC2(O)CCCC2)cc1 +CC(C)(C)C(=O)NCC(=O)Nc1ccc2c(c1)OCCCO2 +Cn1cnnc1SCC#CCOC(=O)c1cc2ccccc2o1 +Cc1sc2ncnc(SCc3ccco3)c2c1C +COC(=O)N1CCCC(C(=O)Nc2ccc(-c3ncc[nH]3)cc2)C1 +O=C(CC1C=CCC1)Nc1nc2cc3c(cc2s1)OCCO3 +COc1ccc(CC(=O)Oc2ccc(C#N)cc2)cc1OC +O=C(Nc1ccccc1)C1COc2ccccc2C1 +CC(=O)Oc1ccc(C(=O)c2cncc(Br)c2)cc1 +CN(C)S(=O)(=O)N1CCC(Cc2cccc(C(N)=O)c2)C1 +CCOc1ccccc1CNC(=O)Cc1nc(-c2ccccn2)n[nH]1 +CCC(C)(C)C(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 +C=CCCCN(C)C(=O)Nc1cccc(C(=O)N2CCCCC2)c1 +Cc1occc1-c1nnc2sc(Cc3ccccc3)nn12 +COc1ncccc1N(C)C(=O)c1ccc(F)c(SC)c1 +CC(C)(C)OC(=O)N1CCCC1C(=O)N1CCCCC1 +OC(CCNc1cccc(C(F)(F)F)c1)C(F)(F)F +COc1cccc(COC(C)C(=O)N(C)c2nccs2)c1 +O=C(CCC1CCCC1)Nc1cc(-c2ccsc2)no1 +COc1ccc(-c2nc(-c3ccc(O)c(N)c3)n[nH]2)cc1 +CCOc1cc(C(=O)N(C)Cc2cccc(Cl)c2)ccc1OC +COc1cccc(C(=O)N2CCC(C)(O)C2)c1F +O=C(NC1CC(CO)OC1=O)OCc1ccccc1 +c1cn(CCc2noc(C3CC3)n2)c(-c2ccc(-c3cc[nH]n3)o2)n1 +CC1(C)C(NC(=O)c2ccccc2-n2cnnn2)C2CCOC21 +O=C(Nc1ccccc1C(=O)NC1CC1)c1ncn(-c2ccccc2)n1 +CC(=O)NC(C(=O)Nc1cccc(Cl)c1)C1CCCC1 +Cn1ncc2c(NCc3ccccc3Cl)nc(NCCO)nc21 +CCOC(=O)c1nnsc1-c1cn(-c2ccc(Cl)cc2)nn1 +Cc1ccc2nc(COCC(=O)N3CCNC(=O)C3CCO)[nH]c2c1 +CC(Oc1ccc(F)cc1F)C(=O)Nc1ccccc1C#N +Nc1cc(N)nc(SCC(=O)NCc2ccc(Cl)cc2)n1 +N#Cc1nnn(Cc2ccccc2Cl)c1C1CCCO1 +CC(C)N1CC(C(=O)N(C2CCCC2)C2CC2)CC1=O +CC1(C)CN(Cc2c(Cl)ccc3cccnc23)CCO1 +CN(C)c1cc(C(=O)NCCc2ccc3c(c2)OCO3)ccn1 +CN(C)C(=O)CCNC(=O)C1CCCCN1C(=O)c1cccs1 +CC(C)Sc1ccc(C(O)C(=O)NC2CC2)cc1 +Clc1ccc(C=Cc2nn3c(-c4cnccn4)nnc3s2)cc1 +Cc1noc(Cc2ccccc2NC(=O)c2ccco2)n1 +CCCNC(=O)CN(CC)S(=O)(=O)c1ccc(F)cc1 +NC(=O)Cn1cc(NC(=O)C(OC2CCCC2)c2ccccc2)cn1 +CCc1nn(C)c(CC)c1S(=O)(=O)N=c1cc(C)cc(C)[nH]1 +CC(C)(C)OC(=O)Nc1ccc(C(F)(F)F)cc1N +NC(=O)c1c(NC(=O)Cc2ccc3c(c2)OCO3)sc2c1CCC2 +C#CCNC(=O)c1cc2cnccc2nc1C(F)(F)F +Cc1ccc(C(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)cc1F +CNS(=O)(=O)c1ccc(C(=O)N2CC(C)c3ccccc32)cc1 +COc1ccc(NC(=O)c2cnn(C)c2-n2cccc2)c(OC)c1 +CC1CCN(C(=O)c2ccc(NC(=O)N3CCCC(C)C3)cc2)CC1 +COCc1nc(-c2cccnc2)nn1-c1ccc(OC)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1ccnc(N(C)C)n1 +Cc1cc(OCCNS(=O)(=O)c2ccccc2)ccc1N +O=S(=O)(NCc1cscn1)c1ccc(F)cc1 +CCOC(=O)CCCC(=O)Nc1ccc(Cl)cc1 +COCC(=O)NC(C(=O)N(C)Cc1ccccc1F)C(C)C +Cc1ccc(C)c(NC(=O)C(C)n2ncc3ccccc3c2=O)c1 +COc1ccc(C2CC(=O)c3cnn(-c4ccccc4)c3C2)cc1OC +CC(C)CC(=O)N1CC(=O)N2CCc3ccccc3C2C1 +Cc1cccc(-c2nc(C3CC(=O)N(Cc4ccccc4)C3)no2)c1 +CC(c1ccco1)N(C)S(=O)(=O)c1cccc(C#N)c1 +COC(=O)c1ccc(CNC(=O)CCc2ccccc2F)cc1 +Cc1nc2nnc3ccc(C(=O)N(C)C)cc3c2n1C1CCCC1 +O=C(Cn1cnc2ccc(Cl)cc2c1=O)Nc1ccc(F)cc1F +CC(=O)NCc1ccc(C(=O)N2CCCCCC2c2ccco2)cc1 +CCN(C(=O)CNc1cccc(Cl)c1Cl)C1CC1 +Cc1nnc(-c2cccc(-c3cccc4cccnc34)c2)o1 +COc1cc(C(=O)N2CCC(C)CC2)cc(OC)c1C +O=C(Nc1ccc(-n2cncn2)nc1)c1ccc(Br)cc1 +Cc1ncsc1CN1CC(NC(=O)c2cccnc2)CC1CO +Cc1noc(CCC(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)n1 +CCc1cc(C2CCCN2C(=O)Cc2ccc(OC)cc2)on1 +Cc1c(Cl)cccc1NC(=O)c1cccc(-c2nnnn2C)c1 +CS(=O)(=O)c1ccccc1NC(=O)Cc1cccc(F)c1 +NC1(c2nc3c(c(=O)[nH]2)CCCCC3)CCCCC1 +COCCOc1cccc(NC(=O)c2ccc[nH]2)c1 +CCNc1ccc(S(=O)(=O)N(C)C)cc1NCc1nc(C)no1 +O=C(Nc1nc(C2CC2)cs1)C1CC(=O)N(Cc2ccccn2)C1 +Cc1nccn1-c1cc(CNC(=O)NC2COc3ccccc32)ccn1 +O=C(NCc1cccnc1)c1snnc1-c1ccccc1 +Cn1ccnc1CN1CCC2C1CC(=O)N2Cc1ccncc1 +Cc1ccc(C(=O)CCC(=O)NC(C)C(N)=O)s1 +O=C(Nc1cccnc1)NC(c1ccncc1)c1cc(F)ccc1F +Cc1cc(NC(=O)C(Sc2nccn2C)c2ccccc2)no1 +Cc1[nH]ccc1C(=O)Nc1cnn(-c2ccccc2F)c1 +COc1ccnc(NC(=O)c2cc(C)c(F)cc2Cl)c1 +CC(=O)N(CCc1ccccc1)Cc1ccccc1 +CC(=O)c1ccc(-c2ccc(NC(=O)c3ccccn3)cc2)s1 +O=C(c1cccc(OCc2ccccc2)c1)N1CCC(O)CC1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCCC1Cc1ccccc1 +O=C(CNC(=O)c1ccc(Cl)cc1)NCCc1ccccc1 +CCC(C)C(C)NC(=O)c1cn(C)nc1-c1cccs1 +Cc1cc(C)n(-c2ccc(NC(=O)C(NC(N)=O)C(C)C)cc2F)n1 +Cc1cc(C(=O)N2CCCC2)ccc1NC(=O)NCC(C)CC(C)O +COC(=O)C(NCc1c(C)noc1C)c1cccc(C#N)c1 +CC1OCCC1NC(=O)N1CCCCC1CCO +COc1ccc(-c2nc3c(N)nc(N)nc3nc2N)cc1 +CCOc1ccc(C)cc1S(=O)(=O)NCc1ccc2c(c1)OCO2 +CCCSc1ncc(CN2CCN(c3ncc(F)cn3)CC2)cn1 +O=C(CCn1c(=O)sc2ccccc21)Nc1nncs1 +Cc1ccc(C(=O)Nc2ccc(N(C)C)cc2C(F)(F)F)cn1 +CC1(O)c2ccccc2C(=O)c2c1ccc1ccccc21 +CCCC(C)NC(=O)CSc1nnnn1-c1ccc(O)cc1 +CNC(=O)NCC(=O)NCCc1cc(C)ccc1OC +Cc1ccc(CNC(=O)c2noc(C)c2Cn2nc(C)cc2C)cc1 +Cc1csc2ncc(C(=O)Nc3ccc4[nH]ccc4c3)c(=O)n12 +Cc1ccc2c(Br)cnc(N3CCOCC3)c2c1 +NC(=O)c1ccsc1NC(=O)COC(=O)C1CCCCC1 +O=C(c1csc(-c2cccs2)n1)N1CCOCC1C1CC1 +Cc1cnc(C)c(-c2ccc3c(c2)CC(CNC(=O)C2(C)CC2)O3)n1 +CCn1c(=O)c(=O)[nH]c2cc(Br)c(F)cc21 +CC(C)n1nccc1NS(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +CN(C)C(=O)C1(CNC(=O)c2ccc(-n3ccnn3)cc2)CCCC1 +CCSc1nnc(-c2ccc(Br)cc2)n1N +C=CCCCN(C)C(=O)Cc1csc(-c2ccccn2)n1 +CC(C)N(C)C(=O)NC1CCN(c2ccccc2)C1=O +CC(C)(N)c1c(Br)ccc(C#N)c1F +Cc1nnc2n1CCN(C(=O)c1csc(-c3ccccn3)n1)C2 +CCc1n[nH]c(SCC(=O)NC(C)c2ccco2)n1 +c1csc(N2CCN(Cc3ccc4c(c3)OCCO4)CC2)n1 +COCc1noc(-c2ccc(N3CCCC3c3ccccn3)nc2)n1 +CCOc1ccc(-c2cc(Cl)c(C#N)cn2)cc1 +COc1ccc2c(c1)C(c1cccc(C)n1)NCC2 +CCOCc1ccccc1CNC(=O)N1CCCC(NC(C)=O)C1 +CC(CC1CCCC1)C(=O)NCC1(C(=O)N(C)C)CCCC1 +COc1ccc(OC)c(NC(=O)CC2CC3CCC2C3)c1 +Cc1ccnc(NC(=O)c2nn3cccnc3c2Cl)c1 +CCc1ccc(CN2CCC(N3CCOCC3)CC2)cc1 +Cc1cc(C)cc(C(=O)NCC(=O)N(C)Cc2ccccc2F)c1 +O=C(NCC(F)(F)F)N(Cc1ccc(F)cc1F)C1CC1 +Cc1nc(SCC(=O)NC(C)C(C)C)c2ccccc2n1 +COc1ccc(C(=O)N2CCCC2)cc1NC(=O)NC(C)C +CC1CCN(C(=O)CSc2nnc3c(n2)[nH]c2ccccc23)CC1 +COc1ccc2c(C)c(CC(=O)Nc3nc(C)cs3)c(=O)oc2c1 +Cc1ccc(NC(=O)NCC(O)c2sccc2C)cc1C +CCCCOc1nc(C2CCCO2)nc(NC)c1N +CC(C)(C)OC(=O)N1CCCC(NC(=O)NCCn2cccc2)C1 +Cc1cccc(NC(=O)NCC(=O)NC(C)C)c1C +CCn1cc(S(=O)(=O)N2CCCC3(CC=CNC3=O)C2)cn1 +O=C(c1ccsc1)N(CCc1cccs1)Cc1ccoc1 +CC(=O)Nc1cc(NC(=O)COc2cc(C)cc(C)c2)ccc1C +COc1ccc(N2CCN(C(=O)CCCc3cn[nH]c3)CC2=O)cc1 +Nc1ccc(F)c(NC(=O)CCSc2ncn[nH]2)c1 +COc1ccccc1N1CCCC(Nc2ccc3nnnn3n2)C1 +CCN(CC)C(=O)C(C)Oc1ccc2c(C)cc(=O)oc2c1 +O=C(NCCc1ccco1)c1cc(C2CC2)nn1-c1ccccc1 +N#Cc1cnc(SCc2noc(-c3ccc(Cl)cc3)n2)nc1N +CCCC(=O)NCC(=O)Nc1ccc2c(c1)CCC(=O)N2 +CC(C(=O)N1CCCCCC1)N1CCN(c2cnccn2)CC1 +CC(C)NC(=O)Cn1cc(-c2ccccc2)c(N(C)C)n1 +O=C(Cc1c(F)cccc1F)Nc1ccc(N2CCCC2)nc1 +CCN(CC)C(=O)CCC(=O)NCc1ccc(C)c(F)c1 +Cc1cc(CN(C)CCc2ccncc2)ccc1N +COc1ccccc1CNC(=O)CNc1ccc(F)c(C#N)c1 +Cc1ccc(CNC(=O)NC(c2nnc3ccccn23)C(C)C)cc1 +COCCCN(C)C(=O)Nc1ccc(Cl)c(Cl)c1 +O=C(COC(=O)COc1ccc(Cl)cc1)Nc1ccccc1 +COCCn1c(-c2csc(-c3ccccn3)n2)nc2ccccc21 +N#Cc1ccc(-c2noc(C=Cc3ccc(F)cc3)n2)nc1 +O=C(CCc1nc(-c2ccoc2)no1)NCC1CC1c1ccccc1 +CS(=O)(=O)NCC(=O)NCc1ccc(S(C)(=O)=O)cc1 +CC(=O)Nc1cccc(NC(=O)c2ccccc2OC(C)C)c1 +CN(C)c1cc(C(=O)NC2CCN(c3ccccc3)C2=O)ccn1 +Cc1cccc(C(=O)Nc2cccc(C(N)=O)c2)c1C +O=C(Nc1cc2c3c(c1)CCC(=O)N3CCC2)c1cccc(F)c1 +O=C(CCn1cccn1)N1CCN(Cc2cccs2)CC1 +COc1ccc(-c2nc3ccc(N)cc3s2)cc1OC +CCOC(=O)c1ccc(Oc2cnc(-c3ccccc3)nc2)nc1 +CS(=O)(=O)c1ccccc1C(=O)NCCOCC(F)(F)F +O=C(NC12CC3CC(CC(Cl)(C3)C1)C2)N1CCOCC1 +Cc1noc(C)c1C(C)NC(=O)N1CC(C)c2ccccc21 +CC(C)OC(=O)C1CCCN1C(=O)C1COc2ccc(F)cc2C1 +Cc1ccc(S(=O)(=O)Nc2ccc(F)cc2N)cc1 +CCC(C)(O)CNC(=O)Nc1ccc(F)cc1F +CCCC(=O)NCC(=O)N1CCN(c2ccc(O)cc2)CC1 +CN(Cc1cccc(F)c1)C(=O)Nc1ccc(C#N)cc1 +CCc1nnc(SCC(=O)Nc2ccc(C)cc2F)n1N +Cc1nc(C)n(C2CCCN(C(=O)CCCNc3ncccn3)C2)n1 +O=C(NCCc1ccccn1)N(Cc1cccs1)CC1CCCO1 +Cc1cnn(CC(=O)NCc2ccc(-c3ccccc3F)o2)c1 +COc1ccc(S(=O)(=O)N2Cc3cncnc3C2)cc1 +CCC(C)C(=O)CSc1nnc(N2CCCC2)s1 +Cn1cc(CCC(=O)Nc2nc3ccc(Cl)cc3s2)cn1 +CC1CCc2sc(C(=O)NC(C)c3ccncc3)cc2C1 +CNC(=O)c1ccc(NC(=O)NC(C2CC2)C2CC2)cc1Cl +Cn1cc(C(=O)NCc2cccnc2)c2ccccc21 +CCCC1c2cccn2CCN1S(=O)(=O)c1cccnc1 +CC(C)Oc1ccc(CCNC(=O)CN2CCOC(C)(C)C2)cc1 +NC(=O)c1cc(Cl)ccc1NC(=O)Cc1c(F)cccc1Cl +CCCCCNc1ccc(S(=O)(=O)N2CCCC2)cn1 +CN(Cc1ccsc1)C(=O)Cc1csc(Cc2ccccn2)n1 +CC(NC(=O)c1cccs1)C(=O)N1CCc2cc(F)ccc2C1 +Cc1cc(NC(=O)CCn2ccccc2=O)ccc1Oc1cccnc1 +CCOC(=O)NC(C(=O)N(C)CC(C)C#N)C(C)C +O=C(COc1cccc(F)c1)Nc1ccc2c(c1)OCO2 +C#CCOc1ccc(CN2CCNC(=O)C2c2ccccc2)cc1 +O=C1Cc2cc(NC(=O)Nc3ccc4c(c3)OCO4)ccc2N1 +CC(Oc1ccc2ccccc2c1)C(=O)NC1CC1 +O=C(C1COc2ccccc2O1)N1CCCN(c2cccnn2)CC1 +CC(C)CCNC(=O)CCC(=O)NC1CCCC(C)C1C +O=C(COc1ccccc1F)NCC1(c2ccccc2)CCOCC1 +CC(C)OCc1c(C(=O)NCC(F)(F)F)oc2ccccc12 +Nc1nc(C2CCCO2)ncc1C(=O)Nc1ccncc1 +CCC(CC)c1c(C#N)nnn1-c1ccc(F)cc1 +CC(C)C(=O)NCCNC(=O)C1CCN(c2ccc(C#N)cn2)CC1 +CCOc1cc(N)cn2cc(-c3cc(C)ccc3OC)nc12 +O=c1[nH]c(Nc2ccc(F)c(F)c2)nc2c1CCCC2 +Cn1cnnc1CNC(=O)COc1ccc(N2CCCC2=O)cc1 +CCC(C)c1cc(C(=O)N2CC(=O)Nc3ccccc32)on1 +O=C(CC1CCCC1)NCCn1c(=O)oc2ccccc21 +Cc1c(Br)cc(Cl)c2c1NC(=O)CC(C)O2 +O=S(=O)(NCC1(O)CCOCC1)c1cc(F)cc(F)c1 +COc1cc(OC)cc(C(=O)NCc2ccc(C)cc2C)c1 +CC(C)N1CC(NC(=O)c2ccc(CSc3ncn[nH]3)o2)CC1=O +Cc1ccc(C(C)NC(=O)c2ccc(S(C)=O)cc2)o1 +CCc1ccc2c(c1)S(=O)(=O)N=C(NCc1cccnc1)N2 +CC(=O)c1ccccc1C(=O)N1CCC(Nc2cccnc2)CC1 +CCN(CC)c1ccc(C(=O)Oc2ccc(NC(C)=O)cc2)cn1 +Cc1cc(C)c2nc(-c3cnn(C)c3)cc(C(=O)N3CCCC3C)c2c1 +O=C(Cc1csc(-n2cccc2)n1)N1CCc2ccccc2C1 +Cc1ccc(C(=O)NC(c2ccc(F)cc2)C2CCCO2)c(=O)[nH]1 +COC(CNC(=O)Cc1ccc(C)nc1)c1ccccc1 +CC(=O)NCCNc1nc(-c2cccs2)nc2sc(C)c(C)c12 +COCCn1cnnc1CCn1ccnc1-c1ccccc1Cl +COC(=O)c1cc(Cn2cnc3cc(F)c(F)cc32)c(C)s1 +O=c1c2ccsc2ccn1Cc1nc2cc(F)ccc2o1 +CC(=O)Nc1ccccc1-c1ccccc1N(C)C +N#Cc1ccc(OC2CCN(C(=O)CCCc3ccccc3)CC2)nc1 +CCCOC(=O)c1cc(-c2cc(F)ccc2F)nn1CCO +CCC(C)Nc1ncnc(NCCC(C)C)c1N +CC(=O)c1ccc(-c2cn[nH]c2-c2cccnc2)cc1 +CCOC(=O)c1cnc(-n2nc(C)cc2C)nc1N(C)C +Cn1c(SCC(=O)Nc2cc(F)ccc2F)nc2ccccc21 +Cc1cc(C(=O)N2CCCCC2CCn2cccn2)ccc1Cl +OCCN1CCN(Cc2nc3ccccc3n2C(F)F)CC1 +COCCN1CC(C(=O)N2CCC(c3nc(C)no3)CC2)CC1=O +O=C1Cc2cc(C(=O)CSc3nnc(NC4CC4)s3)ccc2N1 +COC(=O)c1ccc(C(=O)Nc2ncc(C)s2)s1 +CCOC(=O)c1nn(-c2ccc(F)cc2)c(=O)cc1N1CCCCC1 +CS(=O)(=O)NCc1nc(-c2ccsc2)no1 +CCCCn1nnnc1CN1CC(C)c2ccccc21 +Cc1csc(NC(=O)CSc2ncnn2-c2ccccc2)n1 +O=S1(=O)CCN(Cc2ccco2)c2c(F)nc(F)c(Cl)c21 +O=C(c1ccccc1F)N1CCCN(C(=O)C2CCC2)CC1 +COc1cccc(NC(=O)C(C)NC(=O)Nc2ccccc2)c1 +Cc1occc1-c1nnc(SC(C)c2nc(C3CC3)no2)o1 +CCC(C)NC(C#N)c1cnn(-c2ccccc2)c1 +Cc1ccc(-c2nc(C)cc(OCC(=O)N3CCCCC3)n2)cc1 +CCc1ccc(CNC(=O)CNC(=O)c2cccs2)cc1 +Cc1cnn(CCC(=O)NC(C)c2ccc3c(c2)CCCC3)c1 +CNC(=O)c1ccc(OC)c(NC(=O)c2cc(C)n(C3CC3)c2C)c1 +COC(=O)c1cc(C#N)c(=O)n(Cc2ccc(SC)c(OC)c2)c1 +CCCNC(=O)CN(C)C(=O)CN1CCOc2ccc(F)cc21 +COC(=O)NCC(=O)N(C)Cc1cc(-c2ccncc2)no1 +COC(=O)C(C)N1CCc2c(cccc2C(F)(F)F)C1 +COc1ccnc(NC(=O)C2CCN(C(=O)C(C)C)CC2)c1 +COc1cc(C(=O)N2CCCC(n3cncn3)C2)ccc1C +COCCN1CCN(C(=O)NCc2ccnn2C)CC1=O +CC(NC(=O)NC1CC1)c1ccccc1C(F)(F)F +Cc1cc(-c2ccc(Br)cc2)n2nc(N)nc2n1 +Cc1cc(F)cc(C(=O)N2CCCC(CO)C2)c1 +Cc1oc(-c2c(F)cccc2Cl)nc1CCO +O=C(NCc1ccco1)c1ccc2c(c1)Nc1nccnc1S2 +O=C(NCC1(CCO)CCOC1)c1cccc(-c2ccoc2)c1 +CCNC(=O)CNC(=O)c1cc2sccc2n1CC +CCS(=O)(=O)NCCCNC(=O)c1ccco1 +CC(=O)N1CCc2cc(NC(=O)COc3cccc(F)c3)ccc21 +CNC(=O)C(CC(C)C)NC(=O)c1c[nH]c(=O)c(Br)c1 +C=CCOc1ccccc1C1NC(=O)c2cccc(C)c2N1 +Cc1cccc(Nc2ccccc2C(=O)NCCS(N)(=O)=O)c1C +CCCCn1nc(-c2ccc(OC)c(OC)c2)cc(N)c1=O +NC(=O)Cc1csc(NC(=O)c2ccccc2OC(F)F)n1 +O=C1C(N2CCc3ccc(F)cc32)CCN1C1CC1 +CCOC1CCCN(C(=O)Nc2cccc(N)c2)C1 +CC1CC(C)CN(C(=O)NC(C)c2nncn2C)C1 +CC(NC(=O)c1nccnc1N)c1ccc(NC(=O)C2CC2)cc1 +O=C1CCC(C(=O)NCCOc2ccc(Cl)cc2)N1 +N#Cc1ccc(Cl)c(NC(=O)c2cn(-c3ccc(F)cc3)nn2)c1 +COc1ncccc1CNC(=O)Nc1ccc(C)cc1F +Cn1c(=O)ccn(CC(=O)NCC2CCCc3ccccc32)c1=O +Cc1nc(CNC(=O)c2cnc(-c3ccccc3)nc2C)c(C)s1 +O=C1NCCCCC1Sc1nccn1-c1cccc(F)c1 +Cc1ccc(C(CNC(=O)C2CCCCC2)OCCO)cc1 +Cc1nnsc1C(=O)N1CCC(CNS(=O)(=O)C(C)C)CC1 +CCS(=O)(=O)c1ccc(N2CCCCC2)cc1N +COc1ccc(CN(C)C(=O)CCn2ncc3cccc(C)c32)cc1 +CNc1cc(C(=O)N2CCNC(=O)C2c2cccc(F)c2)ccn1 +CCC(OC1CCCC1)C(=O)N1CCc2c(cccc2NC(C)=O)C1 +COc1cc(NC(=O)c2cc3c([nH]c2=O)CCCC3=O)cc(OC)c1 +Nc1cc[nH]c1Cc1ccccc1Br +O=C(c1ccc(Cl)cc1)N1CC(=O)N2CCc3ccccc3C2C1 +CC(=O)NC1CCCN(C(=O)CCOc2c(C)cccc2C)C1 +O=S(=O)(NCCN1CCc2ccccc21)c1cccnc1 +CCCNc1ncccc1S(=O)(=O)NC(C)(C)CC +O=C(OCc1ccccc1)c1n[nH]c(=O)c2ccccc12 +Cc1ccc(-c2ncco2)cc1NC(=O)NCCc1nc[nH]n1 +CC(CNS(C)(=O)=O)N1CCc2ccccc21 +CCN(CCC(=O)OC)C(=O)c1sc2ccccc2c1Cl +COc1ccc(NC(=O)C(C)c2nc(CO)cs2)cc1 +COc1ccc(Cl)cc1C(=O)Nc1ccncc1 +COc1ccc(F)cc1-c1c(-c2cccs2)noc1N +CC(=O)Nc1cc(NC(=O)Nc2ccc(F)c(C(N)=O)c2)ccc1C +CCN(CC)S(=O)(=O)c1cc(C(=O)N(C)C)ccc1C +Cc1cc(NC(=O)CNC(=O)c2ccccc2)ccc1Br +Cc1ccc(N2C(=O)CCn3c2nc2c3c(=O)[nH]c(=O)n2C)cc1 +CC(C)(CO)Nc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cn1 +CC1Oc2c(cccc2C(=O)Nc2ccc3c(c2)COC3)NC1=O +COCCn1cccc(-c2csc(NC(C)C)n2)c1=O +NC(=O)c1ccccc1NC(=O)c1ccc(Cl)cc1Cl +CCCCCNC1C(=O)Nc2ccc(Cl)cc21 +O=C(CC1CCc2ccccc21)NCCCn1nnc2ccccc21 +Cc1oncc1C(=O)NCC1(c2cccs2)CCOCC1 +CC(C)(C)OC(=O)Nc1ccc(NC(=O)c2ccco2)cn1 +Cc1nn(CC(C)C)c(C)c1S(=O)(=O)N(C)CC(O)C1CC1 +O=C(Cc1csc(NC(=O)c2ccco2)n1)NCc1cccnc1 +CCC(=O)N1CCC(Oc2cnc3ccccc3n2)CC1 +CCCC(=O)c1ccc2c(c1)N(C(=O)CC)CCC2 +COc1ccccc1OCC(=O)N1CCOC(c2ccccc2)C1 +Cc1ccc(C(=O)Nc2ccc(-c3cn4ccccc4n3)cc2)o1 +COCc1ccccc1CNC(=O)NC(C)C(C)C +Cc1ccc(C(=O)NC(C)CCc2ccccc2)c(=O)[nH]1 +COC(=O)c1cc(C)ccc1NC(=O)c1cccc(-n2cnnn2)c1 +CCc1ccsc1C(=O)NCCC(=O)NCc1ccncc1 +Cc1ccc(C)c(Sc2ncccc2C(=O)N2CCCC2)c1 +COC(=O)c1c(C)[nH]c(C(=O)NCC(=O)N2CCCC2)c1C +COc1ncccc1CNC(=O)N1CCC(N2CCOC(C)C2)CC1 +CN(C(=O)c1ccc2c(c1)OCC(=O)N2)c1ccccc1 +CCCCn1c(SCC(=O)c2ccc(C)c(C)c2)n[nH]c1=O +N#Cc1ccc(N2CCC(Sc3ccc(O)cc3)C2=O)cc1 +CCc1nc(NC(=O)NCc2nc(C)c(C)s2)nn1C +COc1ccc(F)cc1NC(=O)COc1ccccc1OC +O=C(NCc1ccccc1)N1CC(c2nc(-c3cnccn3)no2)C1 +CCC(NC(=O)c1cc(=O)n(C)c(=O)n1C)c1cn2cccnc2n1 +COc1cc(Br)c2c(c1OC)CC(C)C2 +NC(=O)Nc1ccc(NC(=O)CCCSc2ccccc2)cc1 +COCCn1c(SCC(=O)Nc2cccc(F)c2)nc(C)c1C +CCCS(=O)(=O)c1ccccc1C(=O)N1CCCCC1 +CCOC(=O)c1cn[nH]c1-c1cccc2ccccc12 +Cc1cc2nc(-c3ccccc3)cc(NC(C)c3nnc(C)o3)n2n1 +COCCOc1ccc(NS(=O)(=O)c2ccccc2Cl)cc1 +CNC(=O)C(NC(=O)Nc1ccc(C)cc1)c1ccc(F)c(F)c1 +COc1ccc(-c2nnc3n2NC2CCCC2S3)cc1 +O=C(Oc1ccccc1)C1CCN(C(=O)c2ccc(F)cc2F)CC1 +CN(CCc1ccc(F)cc1)C(=O)NCC(=O)N1CCCC1 +O=C(Nc1ccc2c(c1)OCCO2)c1cccc(N2CCCC2=O)c1 +CCC(C)NC(=O)CCNC(=O)NC(C)(C)c1cccc(F)c1 +Cc1nnc(NS(=O)(=O)c2cc(Cl)ccc2Cl)s1 +Cc1cc(CN2CCN(C(=O)c3cc(C(C)C)ccc3O)CC2)on1 +O=S1(=O)N=C(NCc2ccc(F)cc2)c2ccccc21 +Cc1noc(C(C)N2CCN(CC(=O)N(C)C3CCCCC3)CC2)n1 +CCOC(=O)c1nnn(C(C)C(=O)Nc2ccccc2)c1N +COC(=O)N1CCC(CNS(=O)(=O)c2cc(F)ccc2F)CC1 +CS(=O)(=O)c1cccc(NCC(=O)NC2(C#N)CCCCC2)c1 +FC(F)CN1CCN(CC2=Cc3cc(Cl)ccc3OC2)CC1 +CCOc1ccc(F)c(C(=O)NCCC(=O)Nc2ccccc2)c1F +COc1ccc(C(C)=O)cc1CC(=O)Nc1ccc(S(C)=O)cc1 +Cn1nnc2cc(C(=O)N3CCCC3CCc3ccccc3)cnc21 +CC(Oc1ccc(C#N)cc1)C(=O)N1CCc2ccccc2C1 +COc1ccc(OC)c(CNCC(=O)Nc2c(C)cccc2C)c1 +CC(CC1CCCC1)C(=O)Nc1ccc2c(c1)NC(=O)CS2 +O=C(c1ccc(S(=O)(=O)Nc2ccccc2)cc1)C1CC1 +CCOCc1ccccc1NC(=O)c1ccnc(SC)c1 +Cc1cnc(-c2cccc(NC(=O)NCC(C)(C)C(N)=O)c2)o1 +O=S(=O)(Cc1ccc(F)cc1)NCc1ccc2c(c1)OCO2 +CC(C)C(C)NC(=O)N1CCN(C(=O)N(C)C)CC1 +C=CC1CCN(C(=O)NCc2cccnc2-n2ccnc2C)CC1 +CCN1CC(C(=O)N(CC)Cc2ccc(C(=O)N(C)C)cc2)CC1=O +Cc1cc(C)c(C(=O)NCCC(O)c2ccco2)c(C)c1 +CCOC(=O)C(C)c1cc(OC)c(OC)c(OC)c1 +Cc1n[nH]c(-c2cccc(OCCC(C)C)c2)c1CO +CCN1C(=O)c2ccccc2NC1c1ccc2c(c1)OCCO2 +CCOC(=O)CCNC(=O)Nc1cccc(OC)c1 +COCc1cc(C)n(CC(=O)N2CCC(C)CC2)c(=O)c1C#N +CCCn1c(SC(C)C(=O)N2CCCCC2)n[nH]c1=O +CC(O)(CNC(=O)c1ccc(F)cc1Cl)C1CC1 +OCCNc1nc2ccccc2n1Cc1c(F)cccc1Cl +O=C(CC1OC(=O)c2ccccc21)Nc1ccc(-c2cc[nH]n2)cc1 +CC1(C)C2CCC1(C)C(NC(=O)NCCOCC(F)(F)F)C2 +CCCSc1nc(=O)c2c(n1C)NC(=O)CC2c1ccc(F)cc1 +O=C(Nc1ccc2c(c1)C(=O)Nc1ccccc1O2)c1cnccn1 +CC1CCCN(C(=O)c2c[nH]c3ccccc3c2=O)C1 +Cc1ccc(C2CC(=O)Nc3c2cnn3C(C)C)cc1C +Cc1noc(C(C)OC(=O)c2cccc(C(F)(F)F)c2)n1 +CN1CCN(C(=O)CCc2ccco2)C(c2ccccc2)C1 +Cc1cc(C(=O)N2CCOC(C)C2)c(C)n1Cc1ccccn1 +COc1ccnc(NCC(=O)Nc2ccc(Cl)cc2)n1 +O=C(Nc1cc(Cl)ccc1F)c1ccsc1 +CC(C)Oc1ccccc1NC(=O)C(C)NS(C)(=O)=O +Cc1ccsc1C(=O)Nc1cnn(CC(F)(F)F)c1 +Cc1c(C(C)NC(=O)c2cncc(Br)c2)cnn1C +COc1ccc(-c2nnc(SCCO)n2-c2ccccc2)cc1 +CNC(=O)Cc1ccc(NC(=O)N(C)CCc2ccccn2)cc1 +CC(C)(CCCNc1nn2c(=O)ccnc2s1)C1OCCO1 +Cc1nn(C)cc1S(=O)(=O)Nc1ccc2ccccc2c1 +CC(Nc1nc2cccc(Cl)c2s1)C(=O)N(C)C +CCNc1cc(C(=O)N2C(C)CCCC2C)ccn1 +CC1CN(C(C)CNC(=O)c2nccnc2N)CC(C)O1 +Cc1ccc(N2CC(C(=O)N3CCC(C(N)=O)CC3)CC2=O)cc1 +CCC(C)NC(=O)N1CCN(c2ncccc2C#N)CC1 +Cc1sc2nc[nH]c(=O)c2c1-c1ccc(F)cc1 +COC(=O)c1ccc(C)c(C(=O)Nc2ccccc2)c1 +Nc1ccccc1OCc1nc(-c2cccs2)no1 +CCC(C)NC(=O)c1cc(Br)ccc1N +O=C(CCc1cnn(-c2ccccc2)c1)OCc1ccccn1 +CC(NC(=O)c1cccc(N2CCCC2=O)c1)c1nnc2ccccn12 +CCn1c(C)c(C(=O)COc2ccc(F)cc2)c(C)c1C(=O)OC +CCc1cccc(NC(=O)Cn2cnc3sc(CC)cc3c2=O)c1 +CCOc1cc(C)c(C)cc1S(=O)(=O)NC(C)C +CCC1Oc2ccccc2N(CC(=O)NCc2cccs2)C1=O +CCCNC(=O)C1(c2cc(-c3cccc(OC)c3)on2)CC1 +CC(C)c1[nH]c(-c2cccc3c2OCO3)nc1C#N +OC(COc1cccc2c1CCCC2)CN1CCOCC1 +COc1cccc(NC(=O)C(C)Sc2ccc3c(c2)OCCO3)c1 +COC(=O)c1ccc(S(=O)(=O)Nc2ccc3c(c2)OCO3)cc1 +NS(=O)(=O)CCNC(=O)C1CC1c1ccc(F)cc1 +Cc1csc(Cn2c(N)nc3cc(F)ccc32)n1 +Cc1cnc(C(Nc2ncnc3c2oc2ccccc23)C2CC2)s1 +Nc1cccc(-c2nc3cc(Br)cnc3o2)c1 +Cc1cc(C)cc(CN2CCN(C(=O)c3ccc(N)nc3)CC2=O)c1 +CCN(CC)C(=O)CCCNc1nc(C)nc2sc3c(c12)CCC3 +CC(CCOc1ccccc1)C(=O)N1CCCC(O)C1 +O=C(c1ccc(-n2cccc2)cc1)N(Cc1ccc(F)cc1)C1CC1 +CNC(=O)Cc1ccc(NC(=O)c2sc(C)nc2C)cc1 +Cc1nn(-c2ccccc2)cc1CNc1nnc(C(C)(C)C)o1 +O=C(c1cccc(F)c1)N1CC(c2nc(-c3ccncc3)no2)C1 +COc1cc(NCc2ccc(Cl)cc2)nc(C2CC2)n1 +COc1ccc2c(CC(=O)N(C)Cc3ccc(O)cc3)coc2c1 +Cc1ncsc1CNC(=O)N(C1CC1)C(C)c1ccco1 +O=C(C1CC1)N1CCN(Cc2nc(C3CC3)no2)CC1 +COc1cc(COC(=O)c2ccoc2C)ccc1OC(F)F +COC(=O)c1ccc(N(CC2CC2)C(C)C)c(N)c1 +COc1ccc(Cl)cc1NC(=O)Cc1cc(-c2ccco2)on1 +Cc1ccccc1CNC(=O)Nc1cnn(CC(F)F)c1 +Cc1nn(CC(=O)OC(C)C)c(C)c1CN1CCOC(C#N)C1 +Cn1ccnc1SCc1cccc(C(=O)Nc2nc[nH]n2)c1 +Cc1ccc(S(=O)CC(=O)Nc2ccc(C)cc2C)nc1 +Cc1occc1C(=O)Oc1cccc(C(=O)N(C)C)c1 +Cc1noc(C)c1COC(=O)CCc1ccc2ccccc2n1 +CN(Cc1ccco1)C(=O)c1cn(Cc2ccccc2)c2ccccc12 +Cc1cccc(C(=O)NCC(=O)N(C)CC(O)C2CC2)c1 +Cc1ccc(NC(=O)CN(C)C(=O)C2(c3ccccc3)CC2)cc1 +O=C(Cc1ccc(O)cc1)N(Cc1ccco1)Cc1cccs1 +COCCCNC(=O)C(N)c1ccc2c(c1)CCO2 +CNc1ncc(Br)cc1S(=O)(=O)NC(C)C(N)=O +Nc1cccc(OCCNC(=O)c2ccc(F)c(F)c2F)c1 +CCn1cnnc1CNC(=O)C1CCCN(C(=O)c2cccs2)C1 +Cc1nc(CSc2nc3ccccc3n2C)oc1C +CCOC1CC1C(=O)NC1CCCOc2ccccc21 +Cc1ccc2c(c1)C(O)CC1(CCN(c3ncccn3)CC1)O2 +CCOc1ccccc1NC(=O)COc1cccc(C#N)c1 +CC(C)c1cc(NC(=O)CN(C)C(=O)c2cccs2)[nH]n1 +CCCNS(=O)(=O)c1ccc(NC2CC2)nc1 +Cc1cccc(C)c1OC(=O)Cn1c(=O)n(C)c2ccccc21 +O=C(Nc1cccc2cn[nH]c12)c1ccc2ncsc2c1 +Cc1nnc(SCCCOc2ccccc2)n(N)c1=O +CC(=O)NC1CCCN(c2noc(C(C)(C)C)n2)C1 +CC(Sc1nnc(-c2ccco2)n1N)C(=O)N(C)CCC#N +CN(CCc1ccccn1)C(=O)c1ccc(OCc2ccccc2)nc1 +CCC1COC(C)CN1Cc1ccc(O)c(N)c1 +C=CCN(Cc1cccs1)C(=O)NC1CCC(O)CC1 +CCCCc1nnc(NC(=O)N2CCCN(C(=O)CC)CC2)s1 +CC(C)(C)c1n[nH]cc1CNCc1cccnc1-n1cccn1 +CC(C)c1ccc(S(=O)(=O)CC(=O)NCCc2ccccc2)cc1 +CN(CCNC(=O)C1CC(=O)N(Cc2ccco2)C1)c1ccccc1 +CCCn1c(C)nnc1SC(C)C(=O)Nc1ccccc1C#N +CC(=O)NCCNC(=O)NC(C)(C)Cc1ccccc1C +COc1ccsc1C(=O)N1CCCN(Cc2nccn2C)CC1 +CCOC(=O)CN(Cc1cc(=O)oc2cc(C)c(C)cc12)C1CC1 +CCOC(=O)C1CCN(C(=O)c2ccc3nc(C)c(C)nc3c2)CC1 +Brc1cc2c(cc1CSc1ncccn1)OCCO2 +Nc1cc(S(=O)(=O)c2ccccc2)ccc1Cl +CCCc1nnc2sc(-c3ccc(OCC)c(OC)c3)nn12 +COC(=O)C1CCCN(Cc2cn(C)nc2-c2ccncc2)C1 +CC(C)c1ccc(C(=O)N(C)C(C)c2ccc(-n3cncn3)cc2)cc1 +CCCc1ccc(C(=O)NC(COC)C(N)=O)cc1 +CC(C)(C)CC(NC(=O)N1CCC(C(N)=O)CC1)c1ccc(F)cc1 +CCCN(CC(=O)NC)C(=O)c1cc(Cl)ccc1O +CCOC(=O)N1CCC(NC(=O)NCc2ccc(C)cc2C)CC1 +CCc1onc(C)c1C1CCCN1C(=O)CCc1ccc(OC)cc1 +Cc1cccc(Cl)c1NC(=O)CCc1nncn1-c1ccccc1 +CNC(=O)c1ccc(NC(=O)CNC(=O)C(C)(C)C)cc1 +CC(NC(=O)CCC1CCCCC1)c1ccccn1 +Cc1nc(CNC(=O)C(C)n2cccc2)c(C)s1 +O=C(CNC(=O)C1CC1)NC1CCCCC1Cc1ccccc1 +CCC(C)Oc1ccc(-c2ncc(C(=O)NC)c(N)n2)cc1 +O=C(COc1ccc(F)cc1Cl)n1ccnc1 +Cn1cc(NC(=O)NCCSc2ncn[nH]2)cn1 +CN(CCc1cccs1)Cc1cnc2ncccn12 +C#CCN1CCN(C(=O)CNc2ccc3oc(=O)n(C)c3c2)CC1 +CC1CN(S(=O)(=O)c2cccc(Cl)c2Cl)CC(C)O1 +Cc1ccc(CC(=O)NC(C)c2cccc(OC(C)C)c2)cn1 +CCn1cnnc1CNC(=O)COc1ccccc1F +CC(NC(=O)c1ccnc(OC2CCC2)c1)C(=O)Nc1ccccc1 +CC(c1cccs1)N(C)S(=O)(=O)c1ccccc1F +COC(=O)CNC(=O)c1cnn(-c2ccccc2C)c1C(F)(F)F +CC1CN(CC(=O)NCc2ccccc2)c2ccccc21 +Cc1ccc(C2CN(C(=O)NCC(C)c3ccsc3)CCO2)o1 +COc1ccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)cc1 +COc1cc(OC)c2cc(C(=O)N(C(C)C)C3CCC3)[nH]c2c1OC +Nc1ccc2c(c1)C(=O)N(c1cccc(Cl)c1Cl)C2 +CCS(=O)(=O)c1cccc(NC(=O)NCc2ncc[nH]2)c1 +CC1CC(C)CN(C(=O)C(C)Sc2nnnn2C)C1 +CCN(CC)C(=O)N1CCN(C(=O)Cc2ccc(Cl)cc2)CC1 +Cc1cnn(C(C)C(C)Nc2ncnc3ccccc23)c1 +CC(C)(C)NC(=O)c1ccc(Cn2ccccc2=O)o1 +Cc1ccc(NC(=O)CCCN(C)C(=O)OC(C)(C)C)cc1F +CC(C)n1nnnc1SCC(O)COc1cccc2ccccc12 +COc1ccc(CN2CCN(c3nnc(C4CC4)s3)CC2)cc1 +Cc1cccc(NC(=O)CCc2csc(-c3ccncc3)n2)c1 +CCn1nnc(NC(=O)c2ccc(Cl)cc2)n1 +CN(CCN(C)C(=O)c1ccn2cncc2c1)C(=O)OC(C)(C)C +Cc1nn(CC(O)COc2ccccc2C(C)C)c(=O)c(C#N)c1C +CC(C)CN1CCOC(CNC(=O)c2cccs2)C1 +CCOc1cccc2cc(C(=O)NCc3ccc(C)cc3)c(=O)oc12 +Cc1ncc(C(C)NCCc2cccc(Cl)c2)s1 +CCC(C(=O)OCc1nc(-c2cccnc2)no1)c1ccccc1 +CCOCc1cccc(NC(=O)c2cc(F)c(F)c(F)c2)c1 +O=C(Cn1cnc(-c2ccccc2)cc1=O)NC1CCCCC1 +CCOC(=O)C1=C(C)N=C(C)C1S(=O)(=O)N=c1ccc(C)c[nH]1 +Cc1nc(CN2CCOC3(CCCN(c4cnccn4)C3)C2)cs1 +Cc1csc(SCc2ccc(C(=O)N3CCOCC3)cc2)n1 +COC(=O)c1ccc(-c2ccco2)n1CC(=O)N1CCCCC1 +Cc1cnc(CCNC(=O)NC(C)CC(O)c2ccco2)s1 +Cc1ccc(C)n1-c1c(C(=O)OCCc2cccnc2)cnn1C +CCOc1ccc(C(=O)Nc2ccc3nc(C)oc3c2)cc1 +O=C(c1cccnc1)N1CCN(Cc2ccccn2)CC1 +Cc1ccc(CN(C)C(=O)c2ccc(CSc3ncn[nH]3)cc2)o1 +CCN(CCC#N)C(=O)COc1ccc(F)cc1F +CCN1CC(C(=O)NC(c2ccc3c(c2)OCCO3)C(C)C)CC1=O +NC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(-n2cccn2)cc1 +O=C(c1cn2cccnc2n1)N(Cc1ccco1)CC(F)(F)F +CCC1CN(c2ncc(Br)cn2)CCO1 +CCSc1nc(CC(=O)NCc2ccc3c(c2)CC(C)O3)cs1 +CN(Cc1ccno1)C(=O)CCCc1ccc(Cl)cc1 +COc1cc(CCNC(=O)Cn2ncc3ccccc32)ccc1C +Cc1cc(CN(CCC2=CCCCC2)Cc2cc(C)on2)no1 +NS(=O)(=O)CC1CCCN(Cc2nc3ccccc3s2)C1 +Cc1cc(OCC(=O)N(C)c2ccccc2)nc(N2CCCC2)n1 +Nc1cc(N2CCc3onc(-c4ccc(F)c(F)c4)c3C2)ncn1 +CC(c1cccc(O)c1)N(C)S(=O)(=O)c1c[nH]cn1 +CC1CCCCN1C(=O)Cn1cc(C(F)(F)F)cc(Cl)c1=O +COCCNC(=O)c1cc(C(C)C)nc(N(C)C)n1 +O=C(COc1ccccc1F)NCc1nc(-c2ccccc2)no1 +COc1ccc(NC(=O)c2cc(C)nc3ccccc23)cn1 +Cc1cccc(C)c1NC(=O)CNc1ccccc1N1CCCC1=O +Cc1noc(C)c1CN1CCOC2CN(C(=O)c3cccnc3)CC21 +Cc1cc(C)c(S(N)(=O)=O)cc1C(=O)NC1CC1 +CCC1CCCN(C(=O)NCCNC(=O)c2ccc(F)cc2)C1 +NS(=O)(=O)CCNC(=O)C1CC1c1ccccc1F +CCn1nc(C(C)C)cc1C(=O)NCC(O)c1ccccc1Cl +CC(=O)NCCCN(C)C(=O)c1c[nH]c2cccc(F)c12 +COc1ccc(C(=O)C(C)N2CC(C)OC(C)C2)cc1N +CC(C)(C)c1cc(CN2CCN(c3ncc(C#N)c(N)n3)CC2)n[nH]1 +Cn1cc(C(=O)N2CCCC2CCc2ccccc2)ccc1=O +CCC(=O)NCc1nc2ccccc2n1CC(=O)N1CCCCC1 +Cn1cc(CCC(=O)N2CCC(C(=O)N3CCCCC3)CC2)cn1 +CC(NC(=O)c1ccc(Cl)c(N)c1)c1cccnc1 +COc1ccccc1NC(=O)Cc1ccccc1C +Cc1cccc(C(=O)NCc2ccccc2S(=O)(=O)N(C)C)c1 +CC(C)Cc1nnc(NC(=O)c2nn3ccccc3c2Cl)s1 +COc1cccc(CNC(=O)c2ccc(-n3ccnn3)cc2)n1 +CSc1ccccc1NC(=O)COc1ccccc1C#N +COCCN(CCC#N)Cc1ccc(F)cc1F +COc1ccc2nc(NC(=O)CCn3ccc(C)n3)sc2c1 +COC(=O)c1cc(NC(=O)NCC2CCC2)ccc1Cl +CCCN1Cc2cc(N)c(OC)cc2CS1(=O)=O +Cc1ccc(CN(C)C(=O)c2cc(=O)c3ccccc3o2)o1 +COCC1CN(C(=O)c2ccc(C)nc2)Cc2nnn(CC3CC3)c21 +O=C(NCc1cn(-c2ccccc2)nn1)Nc1cccc(Cl)c1F +O=C(Nc1ccc(F)cc1)NC1CCN(C(=O)c2cccc(F)c2)C1 +CC(Nc1cn[nH]c(=O)c1Cl)c1c(F)cccc1Cl +Cc1nc2cc(CC(=O)NCC(=O)NC3CC3)ccc2[nH]1 +CC(C)CNC(=O)c1cnn(-c2ccccc2)c1N +Cn1ncc2c(=O)[nH]c(NC(c3ccccc3)c3ccccn3)nc21 +Cc1cccc(C(=O)N2CCn3c(nnc3C(C)C)C2)c1-n1cccc1 +O=C(c1ccc[nH]1)N1CCC2(CC(Nc3ncccn3)CO2)C1 +CC(C)OCCOc1ccc2scnc2c1N +CC(C)c1noc(-c2ccc(N(C)Cc3cccnc3)nc2)n1 +O=C(NCCOc1ccc(F)cc1)c1ccc(F)c(F)c1 +CCC(=O)N1CCc2cc(CNC(=O)C3CCC3)ccc21 +Nc1cc(C(=O)N(CC(F)(F)F)C2CC2)ccc1Cl +CCCN(CCC)C(=O)CSc1ccc(O)cc1 +Cn1c(CCNC(=O)c2c[nH]c(=O)c3ccccc23)nc2ccccc21 +OC(CN1CCOC(Cn2cncn2)C1)c1cccc(F)c1 +Cn1cnnc1CCc1cccc(Br)c1 +Cc1cc(C)c(C(=O)N2CCc3cc(F)ccc3C2)o1 +CCOC(=O)N1CCN(C(=O)CSc2ccccc2F)CC1 +CC(=O)c1cccc(NC(=O)N2CCCC2c2c(C)n[nH]c2C)c1 +Cc1ccc(OCC(=O)Nc2nc(-c3ccccn3)cs2)cc1 +Cc1csc(C(C#N)C(=O)C2(c3cccc(F)c3)CCCC2)n1 +N#Cc1nnn(CCCCOc2ccccc2)c1C1CC1 +O=C1CC2(CCN(C(=O)Cc3ccncc3)CC2)CN1 +CC=CC(C)=CC(C)C(=O)CC1CC(CC(N)=O)CC(=O)O1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cccc2ccoc12 +O=c1[nH]ncc(NCC2COc3ccccc3C2)c1Cl +CNC(=O)C1CCN(C(=O)Nc2ccc(F)cc2OCC2CC2)CC1 +COCCNc1c(C(=O)OC)c(=O)[nH]c2c(Cl)cccc12 +COCCOc1cc(NC(=O)c2cc(C)oc2C)ccc1OC +CC(C)(C)OC(=O)NC1CCNC1c1ccncn1 +Cc1csc(NC(=O)CCC2NC(=O)c3ccccc3N=C2O)n1 +Cc1cc(C(=O)NCc2ccccc2Cl)c(C)o1 +Cc1cc(N2CC(n3cc(-c4ccccc4)nn3)C2)n2ncnc2n1 +Cn1c(C(=O)NC2CCN(S(C)(=O)=O)CC2)cc(=O)n(C)c1=O +CC(C)C(C)N(C)S(=O)(=O)c1ccc(O)c(N)c1 +CCCCCSc1nnc2nc(C)cc(C)n12 +Cc1nc(C(C)N(C)C(=O)c2c[nH]nc2C2CCCCC2)c(C)s1 +CCn1c(=O)n(CC(=O)Nc2ccc3c(c2)OCO3)c2cccnc21 +CCOC(=O)c1csc(NC(=O)C(C)n2nc(C)ccc2=O)n1 +CC(C)Nc1cccc(CNC(=O)C2CC(=O)N(C(C)C)C2)c1 +Cc1cc(C)n(CC2CCCN2Cc2nc3c(F)cccc3[nH]2)n1 +CC(C)(C)NC(=O)CCn1ncc2c(Cl)cccc21 +CCOc1ccc(NC(=O)c2cc(Cl)ccc2N)cc1 +CC(C#N)Cn1c(C(C)C)nc2cc(Cl)cnc21 +COc1ccccc1OCCSc1nnc(C)n1N +CCn1cc(C(=O)N2Cc3ccccc3CC2C(N)=O)c2ccccc21 +CC(CO)NC(=O)NCc1ccc(-n2cncn2)cc1 +COc1cc2c(cc1C(=O)N1CC3CCC1CN(C(C)=O)C3)CCC2 +CCNC(=O)N1CCN(S(=O)(=O)c2cc(C)ccc2C)CC1 +CCn1c(N)c(C(=O)CN2CCN(CC(F)F)CC2)c(=O)[nH]c1=O +CNS(=O)(=O)c1cc(C(=O)NCc2ccc(OC)nc2)n(C)c1 +Cc1n[nH]c(=O)c(C(=O)N2CCC(O)CC2)c1C +Cn1nc(CNC(=O)c2ccc3ccccc3c2)cc1-c1ccncc1 +Cc1cc(CNC(=O)CCOc2ccc(F)cc2)c(C)o1 +O=C(CNC(=O)c1cc2sccn2c1)Nc1cccc(Cl)c1 +O=C(NCCNC(=O)c1cccnc1)Nc1ccc(F)c(F)c1 +CCCCc1ccc(NC(=O)c2ccc(=O)n(CC)n2)cc1 +CC(Nc1cnn(C)c(=O)c1Cl)c1ccc(F)c(Cl)c1 +COc1cc(F)ccc1S(=O)(=O)NCc1ccccc1 +CC(C)CNC(=O)N1CCCC(C(=O)NCc2cccnc2)C1 +CS(=O)(=O)N1CCC(CNS(=O)(=O)C2CC2)CC1 +CCN(Cc1ccccn1)CC1(CN2CCOCC2)CCCCC1 +CCN(Cc1cccc2c1OCO2)C(=O)Nc1ccccn1 +O=C(CC1CCCCC1)NCCn1ccc(-c2ccncc2)n1 +CCCC(=O)N1CCCC1C(=O)Nc1cc(C)ccc1OC +O=C(Nc1ccc(S(=O)(=O)Nc2ccccn2)cc1)c1ccco1 +CC1CN2CCCC2CN1S(=O)(=O)CC1CCCCO1 +O=C(Nc1ccc(Cl)cc1)N1CCN(c2ccc(O)cc2)CC1 +COC(=O)Cn1cc(NS(=O)(=O)c2ccc(Cl)cc2)cn1 +Cc1ccc(SCCNC(C(N)=O)c2ccccc2)cc1 +CCn1cc(S(=O)(=O)NCCc2cn(C)c3ncccc23)cn1 +CC(=O)c1ccc(C)n(CC(=O)OCCC(C)C)c1=O +Brc1cccc(CN2CCN(c3ncccn3)CC2)c1 +CCCN(CC1CC1)C(=O)c1ccc2c(c1)NC(=O)C(C)S2 +CCc1cc(S(N)(=O)=O)n(Cc2cccc(F)c2)n1 +COC(C(=O)NCc1cscn1)c1ccccc1 +Cc1nc2ncccn2c1C(=O)N(C)C(C)c1nccs1 +O=C(C1CCCC1)N(CC(F)(F)F)c1ccccn1 +Cc1cc(C)c(NCC(=O)N2CCCCCC2)c(C)c1 +O=C(NCCNS(=O)(=O)c1cccc2nonc12)C1CC1 +Cc1ccc(S(=O)(=O)C2=CCC(C#N)CC2)cc1 +CC(C)=CCn1c(C(=O)N2CCN(C)CC2)cc2sc(C)cc21 +CCN(CC(=O)c1ccc(C)cc1)CC(F)(F)F +Cc1ccc(-n2nc(C(=O)NC(C)C)nc2Cc2ccccc2)cc1 +CC(=O)c1cn(CC(=O)NCc2nc3ccccc3[nH]2)c2ccccc12 +COc1ccc(Br)c(C(=O)N(C)CCC#N)c1 +COc1ccc(C(=O)NCc2ncccc2C)c(OC)c1OC +O=C(CNC(=O)Nc1cnn(CC(F)F)c1)Nc1cccnc1 +CCCS(=O)(=O)NCc1cccc(OC)c1OC +Cc1ccccc1CN(C)C(=O)c1cn2cccnc2n1 +CCC(C(=O)Nc1c(C)n(C)n(-c2ccccc2)c1=O)c1ccccc1 +CC1CN(C(=O)CNC(c2ccc(F)cc2)c2cccs2)CCO1 +COC(=O)N(C)CC(=O)Nc1ccc(F)cc1F +Cc1nn(C)c(=O)c(C(=O)Nc2ncc(-c3ccccc3)s2)c1C +Cc1noc2ncnc(N3CCN(CC(=O)N4CCOCC4)CC3)c12 +O=C(c1ccc(=O)[nH]c1)N1CCCC1c1noc(C2CC2)n1 +Cc1ccc2nc(COC(=O)c3scnc3C3CC3)cc(=O)n2c1 +CNC(=O)c1ccccc1NC(=O)Cc1ccc(F)cc1 +O=C(c1ccc(F)cc1)N1CCC(c2nnc(C3CC3)o2)CC1 +NC(=O)Cn1c(Cc2ccccc2)nn(-c2ccc(Cl)cc2)c1=O +COn1c(-n2nc(C)cc2CC(C)C)nc2ccccc2c1=O +Cc1cc(C)c(OCCCN2CCCCS2(=O)=O)cc1C +CCc1ccc(C(C)NC(=O)Nc2ccn(C)n2)cc1 +Nc1nccnc1C(=O)NCC1(c2cccc(F)c2)CCOCC1 +CCOC(=O)c1c(C)csc1NC(=O)c1ccc(C)nc1 +CC(NC(=O)c1ccsc1)c1ccccc1Cl +Cc1ccc(NC(=O)N2CCC3(CC2)OCCCO3)cc1C +Cc1nc(C(=O)NCc2ccccc2Cl)cs1 +CCN(CC)C(C#N)c1c[nH]c2ccc(OC)cc12 +C=CCNc1cc(-c2ccncc2)nc(-c2cccnc2)n1 +CC(=O)N1CCC(C(=O)Nc2ccc(C)cc2Br)CC1 +Cc1ccc2c(c1)OCC(=O)N2CC(=O)NCC1CCCO1 +CCOCc1ccccc1CNC(=O)c1ccc(OC)cc1 +CCOC(=O)CN1CCS(=O)(=O)c2c(F)c(F)nc(F)c21 +CN(CC1CCCO1)C(=O)CCSc1nnnn1C +c1cnc2ncc(CN3CCC(CN4CCOCC4)C3)n2c1 +Cc1cccc2cc(-c3noc(CCC(=O)NC(C)C)n3)c(=O)[nH]c12 +Cc1ccccc1-n1ccnc1SCC(=O)Nc1cccnc1 +CCCNC(=O)C(N)c1ccc(OC)cc1OC +CC(=O)NCCCN(C)C(=O)Cc1ccc(F)cc1F +Cc1ccc(CNC(=O)N2CCN(C(=O)c3cccs3)CC2)s1 +COCCC(=O)Nc1cnn(Cc2cccc(F)c2)c1 +COc1ccccc1-c1noc(Cn2ncc3ccccc3c2=O)n1 +CN1C(=O)C(C)(C)COc2c(Br)cccc21 +Cc1ccc(NC(=O)CCNC(=O)c2cnc(N(C)C)cn2)nc1 +CC(C)c1ccc(NS(=O)(=O)c2cccc(N)c2)cc1 +Cc1nc(C(=O)NCc2cc(-c3ccco3)on2)cs1 +COc1ccc(OCCC(=O)NCc2cccc(F)c2)cc1 +CNC(=O)CCc1ccc(NC(=O)c2cccs2)cc1 +CCCCc1noc(CSc2ccncc2N)n1 +Cc1ccccc1C(=O)Nc1ccc(C(=O)NCc2ccco2)cc1 +O=C(CCc1cccs1)Nc1ccccc1CN1CCNC1=O +COc1cccc(NC(=O)COc2cccc(OC)c2)c1 +CCCOc1ccc(-c2cc(C#N)c(=O)n(CCC)n2)cc1 +CS(=O)(=O)c1coc(C(=O)Cc2ccccc2)c1 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(NC(N)=O)cc1 +O=C(NCc1ccc(-c2ccn[nH]2)cc1)NC(C1CC1)C1CC1 +Cc1noc(CCC(=O)NCc2ccc(C)c(F)c2)n1 +COc1ccc(S(=O)(=O)CCC(=O)Nc2cc(C)no2)cc1 +COc1ccc(C(C)NC(=O)c2ccc(=O)[nH]c2)c(OC)c1 +COc1nccnc1N1CCC(N(C)C(=O)c2ccc(C#N)cc2)C1 +Cc1cc(NC(=O)c2ccc(Cl)c(N3CCCC3=O)c2)n(C)n1 +CC(=O)Nc1ccc(C)c(NC(=O)C2CCOC2)c1 +COc1cccc(C(CC(=O)Nc2nc(C)cs2)n2cccc2)c1 +Cc1cc(C(C)NC(=O)NCc2ccnc(OC(C)(C)C)c2)c(C)o1 +CCN(C(=O)c1ncn(-c2ccccc2)n1)c1ccncc1 +CCC1CCC(NC(=O)NCC(C)(C)C(N)=O)CC1 +COc1cc(OC)cc(C(=O)NC(C#N)c2cccs2)c1 +CC(C)N(Cc1ccc(C#N)cc1)C(=O)NCCCN1CCOCC1 +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1cnns1 +CCC(C)c1ccccc1N1CC(C(=O)NCC(C)O)CC1=O +Cc1ncccc1C1NCCc2c1ccc(F)c2O +CCOC1CCCN(S(=O)(=O)c2ccc(C#N)cc2)C1 +O=C1CN(C(=O)CNc2ccccc2OCC2CC2)CCN1 +CC(=O)c1ccc(-c2ccc(C)cc2)n(C(C)C)c1=O +COC(=O)c1cccc(S(=O)(=O)NCc2ncoc2C)c1 +O=C(NCc1ccc(OC2CCCC2)nc1)NCc1ccco1 +O=C(NCCCc1cccc(F)c1)c1ccc(F)nc1 +CN(CC1CCOCC1)S(=O)(=O)c1ccc(C#N)cc1Cl +CC(C)(C#N)S(=O)(=O)c1ccc(Br)cc1 +COc1ccc(CNc2nc3ccccc3o2)cc1OC +COC(=O)CCNC(=O)CN1CCN(c2ccc(F)cc2)CC1 +O=C(Nc1ncccc1O)c1cccc(OCc2ccccc2)c1 +CCOc1cc(CO)cc2c1OC(C)C(=O)N2CC +COC(=O)N(C)c1ccc(NC(=O)c2cnn(C)c2)cc1 +Cc1nnnn1CCC(=O)N(C)Cc1nc2ccc(F)cc2[nH]1 +COCCc1noc(-c2cn(Cc3ccc(F)cc3)nn2)n1 +COCCNC(=O)c1nc2c(o1)CN(S(C)(=O)=O)C2 +Cc1ccc(C(=O)Nc2cccnc2)cc1NS(C)(=O)=O +COC(=O)CNC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +COCCOc1cccc(NCc2ccc(F)cc2)c1 +CNC(=O)c1ccc(CNC(=O)c2cc(OC)cc(OC)c2)cc1 +Cc1ccc(C#N)c(=O)n1CC(=O)N1CCCCCC1 +CC(=O)c1c(C)oc(N)c1C(=O)c1ccccc1F +CNC(=O)C1CCCCN1C(=O)c1ccnc(SC)c1 +CC1CCN(C(=O)CCOc2cccc(N)c2)CC1 +O=C(Nc1ccccc1)Nc1nccn(-c2cccc(F)c2)c1=O +CCOC(=O)C(C)c1cc(C2(C)OCCO2)c(C)o1 +Cc1nc2ccc(C(=O)OCc3nccn3C(F)F)cc2nc1C +CCc1c(C)nc(Cc2ccc(OC)c(OC)c2)[nH]c1=O +O=C(CN1CCN(c2ncccn2)CC1)Nc1cccc(F)c1 +CC(C)N1CCC(NC(=O)c2c[nH]nc2-c2cccc(Cl)c2)C1=O +O=C(COC(=O)Cc1ccsc1)NCc1ccc(Cl)cc1 +Cc1ccc(F)cc1S(=O)(=O)Nc1ccc2c(c1)OCO2 +NC(=O)c1csc(C(=O)Oc2cc(Cl)ccc2Cl)c1 +Cc1cc(C)c(CNC(=O)COCc2ccco2)c(=O)[nH]1 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccc(-n2ccnc2)nc1 +CCc1nc2ccccc2n1CC(=O)N1CCCc2c(N)cccc21 +Cc1nc(NCC2(O)C3CC4CC(C3)CC2C4)c2cnn(C)c2n1 +Cn1cc(-c2noc(-c3n[nH]c(=O)c4ccccc34)n2)cn1 +CCn1nnc2c(N3CC(C(=O)NCc4ccccc4)C3)ncnc21 +CCC(NC(=O)Nc1ccc(OCC(N)=O)cc1)c1cccs1 +Cc1cc(C(=O)Nc2ccc(C(=O)N3CCC(C)CC3)cc2)c(C)o1 +Cc1c(C(=O)Nc2cnn(CC(F)(F)F)c2)oc2ccccc12 +C=CCNC(=O)C1CCN(S(=O)(=O)c2ccccc2F)CC1 +Cc1cccc(NC(=O)N2CCC(S(=O)(=O)c3ccccc3)C2)c1 +Cn1cnc(CNC(=O)NCC(O)c2c(F)cccc2F)n1 +CCOc1ccc(F)c(C(=O)Nc2ccc(OC)c(OC)c2)c1F +Cc1cccc(NC(=O)COc2ccccn2)c1C +CC(C)(C)Oc1cc(CNC(=O)C2(C#N)CCC2)ccn1 +CC(Sc1ncccn1)C(=O)Nc1ccc2c(c1)OCO2 +COc1cccc(C(=O)NCCS(N)(=O)=O)c1 +CSc1ccc(C(=O)NC2CCCN(c3ccccc3)C2=O)cn1 +Cc1c(-c2nc(C3CC3)no2)cnn1-c1ccccn1 +Cc1ccc(-c2ccnc(NC(C)C(N)=O)n2)c(C)n1 +CC(C)CCN1CC(C(=O)N=c2[nH]c3ccccc3[nH]2)CC1=O +Cc1ccc(NC(=O)C2CN(Cc3ccccc3)CCO2)c(Cl)c1 +O=C(NCC1CCN(c2ncccn2)CC1)c1ccccc1 +COc1ccc2c(ccn2CC(=O)Oc2cccc(F)c2)c1 +CCOC(=O)C1(C)CCN(C(=O)Nc2cc(C)cc3cccnc23)C1 +Cc1c(Cl)c(C(F)(F)F)nn1C(C)C(=O)NCc1ccccc1 +CC(=O)Nc1ccc(NC(=O)c2cnc3ccc(C)cn23)cc1 +CCC(=O)Nc1nc2c(OC)cc(NC(=O)CC(C)C)cc2s1 +c1cnc(N2CCC(Cn3cc(-c4ccsc4)nn3)CC2)nc1 +Nc1cc(Cl)c(S(=O)(=O)N2CCOCC2)c(Cl)c1 +O=C(CCNc1ncccn1)N1CCN(c2cccc(Cl)c2)CC1 +CCCN(C(C)C)S(=O)(=O)c1ccc(NCC)nc1 +Cc1nc(CCNC(=O)c2cccc(C#N)c2)sc1C +Cc1nccc(CNC(=O)C(C)OCC2CCCO2)n1 +CNC(=O)C1CC(=O)N(c2ccc3c(c2)Cc2ccccc2-3)C1 +COc1c(C)cnc(CNC(=O)Nc2ccc3c(c2)CCO3)c1C +CCCCCCn1c(CO)cnc1S(C)(=O)=O +CCOc1cc2c(cc1Cn1c(=O)oc3cccnc31)OC(C)C2 +Cc1nc(NCc2ccco2)cc(-c2ccccc2F)n1 +CC(C)c1cc(C2CCN(C(=O)c3cc(F)cc(C#N)c3)CC2)[nH]n1 +CCCCn1nc(C(=O)N(C)C(C)c2ccccc2Cl)ccc1=O +Cc1ccc(CNC(=O)C(NC(N)=O)C(C)C)c(OC(C)(C)C)c1 +COc1ccc(CC(=O)N2CCCN(C(=O)OC(C)(C)C)CC2)cc1 +CC(C)Oc1ncc(C(=O)N2C(C)CCCC2C)cc1Cl +O=C(CC(F)(F)F)c1ccc(Br)cc1 +COc1ccc(CCC2CCCN(C(=O)CNC(N)=O)C2)cc1 +CC(=O)Nc1ccc(NC(=O)c2nn3ccccc3c2Cl)cc1 +Cc1cccc(NC(=O)CN(C)C(=O)C2CC2C)c1C +Cc1cc(C)c(NC(=O)NC2CCN(S(C)(=O)=O)CC2)c(C)c1 +CN(C(=O)CN1CCC2(CC1)OCCO2)c1nc2ccccc2s1 +CSc1nc(C)nc(C)c1C(=O)NCC(C)Cn1nc(C)cc1C +CCCNC(=O)C1(c2cc(-c3ccccc3)on2)CC1 +CC(C)OC(=O)c1cccnc1N1CCC(c2nc[nH]n2)CC1 +CC1COCCN1S(=O)(=O)c1ccc(F)c2ncccc12 +Cc1nc(NC(=O)NCc2cccc(OC(F)F)c2)nn1C +COc1ccc(CN(CC(C)C)C(=O)CNC(C)=O)cc1 +CC(C)Cc1nc(C(=O)NCCc2ccccn2)cs1 +COc1c(C)cc(CN(C)C(=O)CCSc2ccccn2)cc1C +CCC(C)NC(=O)c1ccc(CNC(=O)c2occc2C)cc1 +O=C(Nc1ccc(F)cc1F)c1c[nH]c2ccccc12 +Nc1ccc(C(=O)OCC(=O)c2ccccc2Cl)cc1 +Cn1nc(-c2ccccn2)c(-c2cccc(F)c2)c1N +Fc1ccc2c(c1)CCN(Cc1cn3cccnc3n1)C2 +Cc1occc1C(=O)C(C#N)c1nc(-c2ccc(Cl)cc2)cs1 +CN(CC1COc2ccccc2O1)C(=O)c1ccc(N(C)C)nc1 +CNS(=O)(=O)c1cccc(CNC(=O)N2CCCCC2C)c1 +COc1cc(CNC(=O)c2cc(-c3ccccc3)no2)ccn1 +Cc1noc(C)c1CN1CCc2ccc(Cl)cc2C1 +CCCc1cc(C(=O)N(C)CC2CCCCO2)n(C)n1 +CC(=O)c1ccc(C)n(CC(=O)N2CCCC2)c1=O +COc1ccc(OC)c(CN(C)C(=O)C(C)NC(=O)c2ccoc2)c1 +C#CCOc1ccc(F)cc1NC(=O)Cc1cccc(OCC#N)c1 +CC(C)Sc1ccc(CC(=O)NCc2ccsc2)cc1 +Cc1ccc(C(=O)OCCc2cccnc2)cc1N +N#Cc1c2c(cn(-c3ccc4c(c3)OCCO4)c1=O)CCCC2 +COCc1c(C(=O)NCCc2ccccn2)oc2ccccc12 +CN(C(=O)c1n[nH]c2ccccc12)c1ccccc1 +COCCCNC(=O)CN1CCc2cc(F)ccc2C1 +O=C(NCCc1ccccn1)c1ccc(Br)cc1 +COc1ccccc1CNC(=O)c1ccc2c(c1)C(=O)CCCO2 +CCc1ccc(C2COCCN2S(=O)(=O)c2ccccc2F)o1 +CN(C)c1ccccc1C(=O)Nc1cccc(F)c1 +COc1ccc(C(=O)N2CCN(C(=O)Cc3ccccn3)CC2)cc1 +Nc1cc(C(=O)CN2CCCc3ccccc32)ccc1F +O=C(Cc1cccs1)Nc1cccc(-c2ccn[nH]2)c1 +O=C(CCc1nc2ncccc2[nH]1)NCCc1c[nH]c2ccccc12 +CS(=O)(=O)N1CCN(C(=O)NC2CCCCNC2=O)CC1 +O=C(OCc1ccccn1)C1CCN(C(=O)Nc2ccccc2)CC1 +C=CCN1CCC2(CCCN(C(=O)c3conc3C)C2)C1=O +Cc1cc(C)n(-c2ccc(C(=O)N3CC(C)CC(C)C3)cc2)n1 +Cc1[nH]ccc1C(=O)N1CCOC(c2cccc(OC(F)F)c2)C1 +CCC(C)(CCO)NC(=O)NC1CCN(c2ccc(C#N)cc2)CC1 +COC(=O)C(C)CN(C)C(=O)c1ccccc1SC +COc1cccc(CN(C)C(=O)CSc2ccccc2)c1 +O=C(Nc1ncccn1)C1CC(=O)N(C2CCCCC2)C1 +Cc1noc(C)c1COc1cccc(C(=O)Nc2ccc(C#N)cc2)c1 +CCc1n[nH]c(SCC(=O)Nc2cccc(C(C)C)c2)n1 +COc1ccccc1CCNC(=O)c1cc(S(C)(=O)=O)ccc1C +COC(=O)c1ccc(Cn2cnc(-c3ccc(C)cc3)cc2=O)o1 +Nc1ncccc1C(=O)NC1(c2ccc(Cl)cc2)CC1 +CCC(C)C(NC(=O)c1cc(-c2csc(C)n2)c[nH]1)C(N)=O +CN(Cc1ccncc1)C(=O)NC1CC2(CCC2)Oc2ccccc21 +O=C(NCOC(=O)c1ccc(O)cc1)c1ccccc1 +COc1ccc(CNCc2cc(=O)c3cc(F)ccc3[nH]2)c(OC)c1 +O=S(=O)(c1ccccc1Cl)N1CCOC(c2ccccc2)C1 +OC(Cc1c(F)cccc1Cl)c1ncccn1 +COC(=O)CCCNC(=O)NCc1ccc(C)cc1 +COc1cc(C(C)=O)ccc1OC(=O)Cc1cccc(F)c1F +O=c1[nH]c(N2CCCC2)nc2nccc(-c3ccsc3)c12 +Cc1ccc(C)c(NC(=O)Cc2ccc(O)cc2)c1 +Cc1cc(-c2cncnc2C2CCCN(C(=O)C3CC3)C2)on1 +CCCCn1nc(C(=O)NCC(F)(F)F)c2ccccc2c1=O +O=C(NCC(=O)N1CCc2sccc2C1)c1ccc2[nH]cnc2c1 +N#Cc1ncc(Br)c2cc(F)cc(F)c12 +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)NCCc1cccs1 +O=C1N(c2ccccc2)CC2CN(Cc3ccccn3)CCN12 +CN(C)c1cccc(C(=O)OCC(=O)N(C)c2ccccc2)c1 +CS(=O)(=O)N(CCCC(=O)N1CCOCC1)c1ccc(F)cc1 +CCNC(=O)N1CCC(Oc2nc3c(Cl)cccc3s2)CC1 +Cc1ccc(OCCN2CCCS2(=O)=O)cc1C +CCCCN(CCO)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +C=CCNc1nc(-c2c(N)n(CCC)c(=O)n(C)c2=O)cs1 +CC(C)CN(CC(C)C)C(=O)CSc1n[nH]c(N)n1 +Cc1cc(C)n(-c2nnc(SCC(=O)Nc3ccncc3)n2N)n1 +CCC(=O)Nc1ccc(NC(=O)c2cn[nH]n2)cc1 +CC(C)(C)CC(=O)Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3 +CC(=O)NC1CCCN(C(=O)Nc2cccc(Cl)c2Cl)C1 +CCCn1nc(C(=O)Nc2ccccc2SC(F)F)ccc1=O +Cc1nc(C)c(CC(=O)NC(Cc2ccccc2)C2CC2)c(=O)[nH]1 +CCCc1nnsc1C(=O)Nc1nnc(-c2cc(C)oc2C)o1 +CNS(=O)(=O)c1ccc(C(C)NC(=O)c2n[nH]c3c2CCC3)cc1 +CC1c2ccsc2CCN1C(=O)c1ccc(-c2ccco2)[nH]c1=O +CC(C)Cc1ncc(C(=O)N2CCCCC2C)c(N)n1 +CS(=O)(=O)c1ccc(Oc2cccc(CO)n2)cc1 +CC(NS(=O)(=O)c1ccc2ccccc2c1)C(N)=O +COC(=O)C1(N(C)C(=O)c2c(F)c(F)cc(F)c2F)CCCCC1 +Cc1cc(C)n(CCc2nc(-c3ccc(CO)cc3)no2)n1 +Cc1ccc(-c2nnn(CC(=O)NCCc3ccccc3)n2)cc1 +NC(=O)C(NC(=O)c1ccnc(OC2CCC2)c1)c1ccccc1 +Cc1cc(C)c(CNC(=O)COc2ccc(F)cc2Cl)c(=O)[nH]1 +NC(=O)c1ccc(C2CN(C(=O)c3cscn3)CCO2)nc1 +CCc1nnc(NC(=O)c2sc3nc4c(cc3c2N)CCC4)s1 +CCOc1ccccc1C(=O)NCc1nncn1CC +CC(C)C(C)NC(=O)COc1ncnc2ccccc12 +Nc1cc(F)ccc1NC(=O)c1ccc(F)cc1Br +Cc1[nH]c(=O)[nH]c(=O)c1Cc1nnc(SCC#N)o1 +O=C(c1ccc2nc(-c3ccc(F)cc3)cn2c1)N1CCCC1CO +Cc1cc(C)c(NS(=O)(=O)c2ccc3c(c2)oc(=O)n3C)c(C)c1 +CC1CCN(C(=O)CC2CSc3nc4c(c(=O)n32)CCC4)CC1 +CN(CC1CC1)C(=O)Nc1cc(F)ccc1Cl +CCNC(=O)c1ccc(Cl)cc1NCC(=O)Nc1cc(C)on1 +Cn1ncc2c(Nc3cccc(Cl)c3)ncnc21 +CCN(CC1CC1)C(=O)Nc1ccccc1C(=O)N1CCOCC1 +O=C(CCCn1ccc2cc(Cl)ccc21)NCC1CCCC(O)C1 +Cc1noc(CN2CCN(C(=O)Nc3ccccc3)CC2)n1 +Cc1[nH]ncc1C(=O)N1CCN(CC(O)c2ccccc2)CC1 +COC(=O)c1cccc(C(=O)N2CCOC(c3ccccc3F)C2)c1 +CCSc1nnc(N)n1CC(=O)Nc1ccccc1C(F)(F)F +CC(C)(C)NC(=O)c1ccc(NC(=O)c2cnc3ccccc3n2)cc1 +Clc1ccc(-c2nnc(N3CCOCC3)o2)cc1Cl +Cc1ccccc1CNC(=O)c1ccc(C#N)cc1 +Cn1c2c(c(=O)[nH]c1=O)C(c1ccc(Cl)cc1)NC(=O)N2 +Cc1ccc(OCc2cccc(C(=O)N(CC(F)F)C3CC3)c2)cn1 +CCSc1nc(N2CCCCC2)c2cnn(CCNC(C)=O)c2n1 +COC1CCN(C(=O)c2ccno2)C1Cc1cnn(C)c1 +CC(=O)NC(C)(C)c1noc(-c2csc(-c3ccoc3)n2)n1 +Cc1oc(-c2ccccc2)nc1CS(=O)(=O)c1nccn1C +COc1ccc(CNC(=O)Nc2cccn(C)c2=O)cn1 +C=CCN1C(=O)c2ccccc2NC1c1cccc2cccnc12 +O=c1n(Cc2ccc(F)cc2)nc(-c2cccs2)n1C1CC1 +CC(CC(=O)OCCc1ccccc1)c1ccc(F)cc1 +CC(CNC(=O)CCc1cc(Cl)cs1)Cn1cccn1 +O=C(c1c[nH]cn1)N1CCC2(CC(Oc3cccnc3)CO2)C1 +CC(=O)c1nc2cc(F)ccc2n1Cc1ccccc1F +COc1ccc(C)cc1NC(=O)CC(C#N)c1ccccn1 +CC(C)Cn1cc(NCc2cnc3c(cnn3C(C)C)c2)cn1 +c1ccc(Cc2noc(-c3cnn(-c4ccccc4)c3)n2)cc1 +CC(O)CN(C)C(=O)COc1ccc(C(C)C)cc1 +O=C(NCc1ccc(C(=O)N2CCCC2)cc1)NC1CC=CC1 +CCCOCc1ccccc1CNC(=O)N1CCOCCC1C +COC(=O)N1CCC(NC(=O)c2cc(C)n(C3CC3)c2C)CC1 +Cc1cc(C(=O)Nc2cccc(F)c2F)cc(S(N)(=O)=O)c1C +Cc1ccc(C(=O)CCC(=O)N(C)CC(=O)NC(C)(C)C)s1 +Cc1csc2ncc(C(=O)NCc3ccccc3)c(=O)n12 +N#CCc1nc2cc(N)ccc2n1-c1ncccc1C#N +O=C(Nc1ccc2c(c1)C(=O)NCC2)Nc1cccs1 +Cc1ccccc1CN1CC2CC(C(=O)NCC3CC3)C(C1)O2 +O=C(NCc1ccnc(-n2cccn2)c1)C1CC(=O)N(C2CC2)C1 +CCOC(=O)Cc1csc(NC(=O)C(C)(C)CC)n1 +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)c1cccc2c1OCO2 +Cc1cccc(NCc2nc(C3CC3)no2)c1C(N)=O +CC1CCCC1NC(=O)N1CCC(C(=O)N2CCOCC2)CC1 +COCCNC(=O)CN1C(=O)COc2ccc(Cl)cc21 +COc1ccc(O)c2c1C(c1ccc(F)cn1)NCC2 +COC(=O)CC(CC(C)C)c1ccc2c(c1)OCCCO2 +CCNC(=O)CN(C)S(=O)(=O)c1ccc(F)cc1F +CN(CC(O)C(F)(F)F)C(=O)NC(c1ccccc1)c1ccco1 +Cc1cc(NC(=O)c2ccc3c(c2)NC(=O)CO3)no1 +Cc1ccc(F)cc1NC(=O)CSc1nncn1C(C)C +CC1COc2c(Br)cc(F)cc2NC1=O +Cc1[nH]ncc1CCCNC(=O)c1cccc2c1ccn2C +NC(=O)c1ccc(Cl)cc1OCc1nc(N)nc(N)n1 +COc1ccc(CNC(=O)NCCNC(C)=O)cc1O +Cc1cccc(Cn2nc(C)c(NC(=O)c3ccc(C#N)cc3)c2C)c1 +Cc1cc(NC(=O)C(C)Sc2nc3c(cc2C#N)CCCC3)on1 +COCc1cncc2c1CCN(C(=O)c1cccn1C)C2 +CCOc1ccc(OCC(=O)NC2CCC(C)CC2)cc1 +O=C(NCCN1CCOCC1)c1cc(Br)ccc1F +NC(c1ccccc1)c1nc2cc(O)ccc2n1C1CC1 +Cc1ccc2cccc(NC(=O)C3CC(=O)Nc4ccccc43)c2n1 +COC(=O)CN(C(=O)c1cnc(C2CCCO2)s1)C1CCCC1 +Cc1cccc(N)c1NCc1cc(F)c(F)cc1F +Cc1ccccc1CC(=O)Nc1cccc(NC(=O)c2ccco2)c1 +CCc1ccc(C(=O)CC2(O)C(=O)Nc3ccccc32)cc1 +Cc1cccc(NC(=O)Cc2cn3ccccc3n2)n1 +CCCCn1nc(C(=O)N2CCOC(CCC)C2)ccc1=O +O=C(NCc1cccnc1)Nc1ccccc1OC1CCCC1 +COc1ccc(C(=O)COc2ccc(Cl)cc2C(N)=O)cc1F +COc1cc(S(C)(=O)=O)ccc1Br +CCS(=O)(=O)NCCNC(=O)C1(c2ccc(F)cc2)CCC1 +CCCN(CC(F)F)C(=O)NC1COc2c(cccc2OC)C1 +Cc1ccc2ncc(C(=O)NCc3cc(F)ccc3F)n2c1 +O=C(NCCc1ccccc1)Nc1cccnc1-n1cncn1 +CCOCC(=O)Nc1scc(C)c1C(=O)OCC +CN(C)C(=O)c1c[nH]nc1C1CCN(Cc2cccnc2)C1 +CCc1ccc(CN(Cc2cccnc2)C(=O)c2cnccn2)cc1 +COc1ccc(CNC(=O)c2ccc(S(=O)C(C)C)cc2)cc1 +COCC1CCCN1C(=O)Nc1cc(F)cc(C(F)(F)F)c1 +COCCOc1ccccc1NC(=O)NCc1ncn(C)n1 +C=CCNC(=O)c1ncc(Cl)c(Cl)c1Cl +COc1cc(CNc2cncnc2C)ccc1Cl +CCCNC(=O)c1cccc(NC(=O)N(C)Cc2ccccn2)c1 +O=C(NCCc1c[nH]c2ccc(Cl)cc12)N(CCO)C1CC1 +CN(CCc1ccccn1)C(=O)C1CNc2ccccc2O1 +O=C(Cn1ccnc1)N1CCCCCC1CC(O)c1ccccc1 +CC(C)c1noc(CCNC(=O)CC(C)(C)c2ccccc2)n1 +CC(=O)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +CCn1c(=O)n(CC(=O)Nc2cccn(C)c2=O)c2ccccc21 +COC(=O)c1ccc(OC)c(NC(=O)N(C)C(C)c2ccon2)c1 +COc1ccccc1-c1nc2ccc(F)cn2c1CC#N +CC(=O)N1CCCC1C(=O)NC1CCOc2c(Cl)cccc21 +CC(=O)Nc1nnc(-c2ccc(S(C)(=O)=O)cc2)o1 +Cc1cc(NC(=O)C(C)C)ccc1NC(=O)c1ccco1 +COC(=O)c1sc(NC(=O)c2ccc(N(C)C)cc2)c(C#N)c1C +Cc1noc(C)c1CN1CCCc2cc(F)c(F)cc21 +CCS(=O)(=O)N1CCC(C(=O)NCc2cccs2)CC1 +CC(C)c1cc(CNC(=O)C2CCCN2C(=O)C2CCCC2)on1 +Nc1cn2nc(COc3ccc(Cl)cc3)sc2n1 +CN1C(=O)COc2ccc(NC(=O)COc3ccccc3)cc21 +CCOCC1CCN(C(=O)C(c2cccc(F)c2)N(C)C)CC1 +COC(=O)c1cc(N2CC(C(=O)OC)CC2=O)ccc1Cl +O=C(c1c[nH]c(=O)[nH]1)N1CCN(c2ccccc2Cl)CC1 +Cc1cc(NC(C)c2nc(CC(C)C)no2)nc(-c2cccnc2)n1 +Cc1ccc(CC2(c3cccc(Cl)c3)NC(N)=NC2=O)s1 +O=C1NCC(C(=O)Nc2nc(C3CC3)cs2)N1 +O=C(CC1CCCC1)NCc1ccc(C2OCCO2)cc1 +COCCNC(=O)c1cc2sccc2n1Cc1ccccc1C +CC(C)NC(=O)Cc1ccc(NC(=O)Cn2cnnn2)cc1 +N#CC(C(=O)Cn1cncn1)c1nc2ccccc2o1 +Cc1cnc(N2CCn3c(CN4CCOCC4)nnc3C2)nc1 +Cc1csc(C(C)NC(=O)N(C)CCOCC2CC2)n1 +Cc1cc(CNc2c(C)cc(O)cc2C)ccc1F +Cc1cccc(C)c1NC(=O)C(C)(C)NC(=O)c1ccccc1O +CC(C)(C)CC(=O)NCC(=O)Oc1ccc(F)c(Cl)c1 +CCCNC(=O)Nc1ccc(CC(=O)N2CCN(CCO)CC2)cc1 +Cc1ccc(OCC(=O)N(CCCO)C(C)C)cc1 +CSc1cccc(NC(=O)c2cc(C)nc3c2c(=O)[nH]n3C)c1 +Cc1ccc(CCNC(=O)c2ccccn2)c(C)c1 +Cc1ccc(CNC(=O)CCC(=O)c2ccc(F)c(F)c2)cc1F +Cc1nc(NCc2ccccc2)c2c(C)noc2n1 +COC(=O)c1cc(-c2cncc(OC)c2)ccc1F +CCN(CC1CCCO1)C(=O)c1csc(Cc2ccccc2F)n1 +CC1(NC(=O)Nc2ccc3c(c2)CCC(=O)N3)Cc2ccccc2C1 +Nc1ccccc1NC(=O)CCCc1cccs1 +Cc1cc(C)c(CNc2cnn(-c3ncccn3)c2)cc1C +Cc1nc(SC(C)C(=O)Nc2ccc(C(N)=O)cc2)nc(C)c1C +C=CCOCC1CCC2C1OCCN2C(=O)c1ccnnc1 +Cc1cccc(S(=O)(=O)NCCC(=O)NC2CCCC2)c1 +COC(=O)Nc1ccc(CNC(=O)NCc2ccccn2)cc1 +CC1CN(C(=O)NCCc2ccccc2F)CC1(O)C1CC1 +Cc1cc(C(=O)CCNc2cccc(C#N)c2)ccc1F +CC(C)n1nnnc1COc1cccc(C(=O)NCC2CCCO2)c1 +Cc1n[nH]cc1CNC(=O)c1ccc(Cl)cc1Cl +CCCn1c(C)nnc1SCc1c(CC)noc1C +CCCn1c(C)nnc1SC(C)C(=O)NCc1ccccc1 +COc1cccc(NC(=O)COc2cccc3ccc(=O)[nH]c23)c1 +Cc1ccccc1NC(=O)Cn1c(C)nc2c(c1=O)CCCC2 +CCNS(=O)(=O)C1CCN(Cc2cnc3c(C)cccn23)C1 +NC(=O)N1CCCC(C(=O)NC2CCCCC2Cc2ccccc2)C1 +Cc1cc(S(C)(=O)=O)ccc1NCc1noc(-c2cccs2)n1 +CC1CN(C(=O)CSc2nnc(-c3cccs3)o2)CC(C)O1 +CCn1cc(C(=O)N(C)C(C)c2ccccn2)cn1 +Cc1nnc(SCc2ccc(C(C)(C)C)cc2)n1CC(N)=O +Cc1cc(C)c2c(c1)CCNC2c1ccc(C)nc1 +Cc1nc(C(C)Nc2ncnc3sccc23)cs1 +COc1cc(OC)c(-c2cnn(C)c(=O)c2C#N)c(OC)c1 +Cc1ccc(-n2ncc(C(=O)NC3CCCCNC3=O)c2C)cc1 +c1c2c(cc3sc(N4CCCC4)nc13)OCCO2 +CC(C)Oc1ccc(CNC(=O)c2ccncc2)cc1 +OC(CCN1CCN(c2ncccn2)CC1)c1ccncc1 +CC(C)Oc1ccc(C(=O)NCc2cccnc2)cc1 +CC(=O)NCc1nnn2c1CN(c1ncc(C)cn1)CCC2 +COC(=O)CCC1CCN(C(=O)OCc2ccccc2)CC1 +COc1ccc(Cl)cc1CNn1nnnc1N +O=C(NCc1ccccc1OC(F)F)c1ccncc1 +Cc1cc(NC(=O)Cn2c(-c3ccccc3)noc2=O)no1 +CN(C)c1ccc(NC(=O)CCn2c(=O)n(C)c3ccccc32)cn1 +COC1CCC(OC(=O)c2scnc2C2CC2)CC1 +CCC1CCc2nc(NC(=O)c3cc(C)no3)sc2C1 +COCCN(Cc1ccsc1)C(=O)c1cc(Cl)ccc1Cl +CCOC(=O)CNC(=O)CN1CCN(c2cccc(Cl)c2)C1=O +Nc1cc(NC(=O)CCn2ccccc2=O)ccc1F +Nc1c(C(=O)c2cccs2)cnn1-c1ccc(Br)cc1 +C=CC(C#N)OC(=O)c1ccc(Cl)cc1Cl +COc1cc(NC(=O)c2ccoc2C)ccc1NS(C)(=O)=O +CS(=O)(=O)N1CCCC(C(=O)Nc2nc3ccccc3[nH]2)C1 +COc1ccnc(NC(=O)c2cc(F)cc3[nH]cnc23)c1 +CCCN(CCC)S(=O)(=O)c1cccc2nonc12 +Cc1ncc(CNC(=O)c2ccc(=O)n(Cc3ccccc3)n2)s1 +Cc1cc(C)n(C2CCCN(C(=O)c3ccc4c(c3)COC4)C2)n1 +CC(C)Cc1nnc2sc(CCc3cnccn3)nn12 +Cc1cccc(NC(=O)C(C#N)Cc2cccs2)c1 +Cc1cc(C)cc(NC(=O)CCN2CC(C)OC(C)C2)c1 +CN(CC1CCCCO1)S(=O)(=O)c1ccc(Cl)cc1 +Cn1cc(C(=O)N2CCCC3CCCC32)c(-c2cccs2)n1 +CCN(CC)c1nc(C#N)cc(-c2ccc(OC)c(OC)c2)n1 +O=C(Nc1cccc(Cl)c1)N1CCOCC1C1CC1 +Cc1ccc(Br)c(NCC(=O)N2CCOCC2)c1 +CC(Sc1nnc(-c2ccccc2)n1N)C(=O)NC1CCCC1 +COCCCCS(=O)(=O)c1ccc2ccccc2c1 +O=C(NCCOc1ccccc1Cl)c1cnc2cccnn2c1=O +Cc1ccc(C(=O)Nc2nc3n(n2)C(c2ccccc2)CC(=O)N3)cc1 +CC(=O)N1c2cc3nccnc3cc2N(C(C)=O)c2nonc21 +Cc1ccc(Oc2ncccc2C(=O)Nc2cc(C)on2)c(C)c1 +CCC(C)NC(=O)c1cc(S(N)(=O)=O)ccc1OC +O=C(NCCS(=O)(=O)c1ccccc1)C1(c2ccc(F)cc2)CC1 +O=C(Nc1nc(-c2cccnc2)cs1)c1cc(=O)[nH]c2ccccc12 +Cn1nnc(NC(=O)c2ccc3c(c2)OCCO3)n1 +Cc1ccc(NC(=O)c2ccn(C)c(=O)c2)cc1S(C)(=O)=O +CCOc1ccccc1CCC(=O)Nc1ccc2[nH]ncc2c1 +CCc1nnc2sc(-c3ccc(N)cc3O)nn12 +COc1ncccc1CN(C)C(=O)c1ccncc1 +Cc1ccc(OC2CCN(C(=O)Nc3cnccc3C)CC2)cc1C +COc1c(F)ccc2c1C(C(=O)c1cccs1)NCC2 +Cn1cnnc1C1CCN(C(=O)c2ccccc2OCC2CC2)CC1 +COC(=O)c1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +O=C(Cc1csc(-n2cccc2)n1)Nc1ccc(F)cc1 +Cc1c(C(=O)NCCCC(N)=O)sc2ccc(F)cc12 +O=C(Nc1nnc(-c2ccco2)o1)C(c1ccccc1)c1ccccc1 +O=S(=O)(NCC1CCC1)c1cc(F)ccc1F +CC(NC(=O)N1CCOC(c2ccccc2F)C1)c1cccnc1 +Cc1ccc(S(=O)(=O)NCCC(=O)NC(C)CO)c(C)c1 +NC(=O)C(c1ccccc1)N1CCn2c(nnc2C2CC2)C1 +Nc1ccc(NC(=O)CCCOc2ccccc2)cn1 +O=C(c1ccccc1F)N1CCN(CC=Cc2ccccc2)CC1 +Cn1c(C(=O)NCc2coc(-c3ccccc3)n2)cc(=O)n(C)c1=O +COCCNC(=O)c1ccc(-c2nc3ccccc3n(C)c2=O)cc1 +COc1ccccc1CC(=O)NCC(O)c1ccccc1Cl +O=C(NCc1nc(-c2ccc(F)cc2)n[nH]1)c1cc(F)ccc1F +COc1ccc(OC)c(CC(C#N)C(=O)Nc2ccc(F)cc2)c1 +CC(C)CCn1nc(-c2cc(F)ccc2F)cc(CO)c1=O +O=C(COC1CCCC1)Nc1cccc(-c2nccs2)c1 +COc1cccc(CCNC(=O)C2COc3ccccc3C2)c1 +CCOc1ccc2nc(NC(=O)c3ccc4nncn4c3)sc2c1 +Cn1cc(CN(Cc2ccccc2C(F)(F)F)C2CC2)cn1 +CCN(Cc1ccccc1)C(=O)CNC(=O)NCc1nc(C)cs1 +CCOC(=O)C(O)(c1ccc(O)c(N)c1)C(F)(F)F +O=C(NC1CCCC1)c1cc(=O)n2c(nc3ccccc32)s1 +Cn1nnc2c(SCc3ccccn3)ncnc21 +O=C(CCC(=O)N1CCCC1)NCc1csc(C2CC2)n1 +O=c1cc(N2CCN(c3ccccc3)CC2)nc2n1CCS2 +CC(=O)Nc1cc(C(=O)CSc2ccccn2)ccc1O +O=S1(=O)c2ccccc2N=CN1Cc1ccccc1 +O=C(NCCn1ncc2ccccc2c1=O)c1cccc2c1NCCC2 +COc1ccc(C(=O)NC(C)C(=O)NCc2cscn2)cc1OC +CC(C)CNC(=O)CNC(=O)c1cc2ccccn2n1 +Cc1nn(C)c(C)c1NC(=O)CNc1ccc(Cl)c(F)c1 +CNc1ccc(Cl)c(Cn2cccc(C)c2=O)n1 +Cn1ccc(CNC(=O)Nc2cccc(N3CCNC3=O)c2)c1 +CCOCC1CCCN(C(=O)c2ccc(C)cc2C)C1 +Cc1nnc(-c2ccc(C(=O)NCC(C)(C)c3ccncc3)cc2)o1 +Cc1ccc2[nH]c(=O)cc(C(=O)N3CC4C5CCC(CC5)C4C3)c2c1 +Cc1cc(C)c(C#N)c(Sc2ccc3c(c2)OCCCO3)n1 +Cc1cccc(C)c1NC(=O)c1c(Br)c(C)nn1C +CCC(C)(C)NC(=O)CCC(=O)c1ccc2c(c1)OCCO2 +COC(=O)N1CCN(C(=O)Nc2cccc(C)c2)CC1 +CN(C(=O)c1cccnc1)c1cccc2ncccc12 +CCc1cc(NC(C)c2nncn2CCOC)n2nc(C)c(C)c2n1 +CCOCc1ccccc1CNC(=O)N(C)C(C)C1CC1 +COC(=O)NCc1ccc(NCc2ccc(S(C)=O)cc2)cc1 +COC(=O)c1c(C)c(C(=O)CN(C(C)=O)C2CCCCC2)c(C)n1C +CN(CC(=O)OCc1cccc(F)c1)S(C)(=O)=O +CC(C)=CCC1(CO)CCCN(S(C)(=O)=O)C1 +CNC(c1ccccn1)c1ccccc1C(F)(F)F +CC(CNC(=O)CC(C)(C)C)N1CCc2ccccc21 +CC(=O)Nc1ccc(C(=O)N(C)Cc2ccc3c(c2)OCCO3)cc1 +CC(C)(C)C(=O)NCCC(=O)NCC1CCN(c2ccc(F)cc2)C1 +COCc1nn2c(C#N)c(-c3ccc(OC(C)C)cc3)nc2s1 +CC1CN(C(=O)Nc2cccc(OCCn3cccn3)c2)CC(C)O1 +O=C(c1cnc2ccoc2c1)N1CCCC(C(=O)N2CCCC2)C1 +Cc1ccc(CNc2cnn(CC(F)(F)F)c2)c(C)c1 +Cc1ccn2c(=NC(=O)Cc3c(C)nn(CC(C)C)c3C)[nH]nc2c1 +COc1ccc(F)cc1C(O)CNC(=O)c1ccccc1C +COc1ccc(Br)c(C(=O)NCc2cn[nH]c2)c1 +CCc1cc(=O)oc2c(C)c(O)c(-c3ccnc(N)n3)cc12 +CCn1nc(C)c(CNc2ncc(C)s2)c1C +Cc1csc(CNC(=O)Nc2cc(C)on2)n1 +CCN1CCN(C(=O)C2CCN(c3cccc(Cl)c3)CC2)CC1 +O=C1CSc2cc(C(=O)NCC(=O)NC3CCCCC3)ccc2N1 +Cc1c[nH]c(=O)n1-c1ccc(C(=O)N2CCCCCC2)cc1 +CC(C)c1ccsc1C(=O)NCCCS(N)(=O)=O +CCC1(C)Cc2ccccc2-c2nc3n(c(=O)c21)CC(C#N)S3 +CC(=O)Nc1cc(NC(=O)NCc2nnc3ccccn23)ccc1C +CC1CN(C(=O)c2cc(Cn3ccc4ccccc43)[nH]n2)CC(C)O1 +O=C(COc1ccccc1)N1CCC(c2nnc3ccccn23)CC1 +CC(C)(C)N1CC(C(=O)Nc2ccc3c(c2)OCO3)CC1=O +CN(CCc1ccc(F)cc1)C(=O)c1cccc(N(C)C)c1 +N#Cc1ncn(Cc2csc(C3CCCCC3)n2)n1 +Cc1cc2c(cc1N)CN(C(C)C)S(=O)(=O)C2 +O=C(CSc1ncc2ccccn12)N1CCN(C(=O)C2CC2)CC1 +COCC(C)OC(=O)c1ccc(Cl)cc1Cl +Cc1ncn(-c2ccc(C(=O)OCc3ccccc3)cn2)n1 +Cc1nc(C)c(C2NCCc3c(F)cccc32)s1 +C=CCNc1oc(C=Cc2cccc(OC)c2)nc1C#N +CC(C)OCCC(=O)Oc1ccc(C#N)cc1Cl +COC(=O)Nc1cccc(OCc2ccc(OC)c(F)c2)c1 +Cc1nc(C)c(C(=O)Nc2ccccc2Cl)o1 +Cc1noc(C)c1S(=O)(=O)NCCc1cnn(C)c1 +CCOc1ccccc1C(=O)OCn1nnc2ccccc2c1=O +O=C1COc2cc(NC(=O)C3CCCCC3C(F)(F)F)ccc2N1 +CCCc1nc(CS(=O)(=O)c2ccccc2C)cs1 +N#CC(c1ccc(F)cc1)N1CCN(C(=O)C2CCCCC2)CC1 +NC(=O)C(NC(=O)NC1CCCC(C(F)(F)F)C1)c1ccccc1 +COC(=O)c1sc2nc(C)nc(N(CCO)CCO)c2c1C +C=CCOc1ccc(C(=O)NCc2ccc(C)cc2)cc1OC +Cc1cc(NC(=O)COc2cccc(C(C)C)c2)no1 +N#Cc1ccc(CNC(=O)NCc2cc3ccccc3o2)cc1 +O=C(Nc1ccc(Sc2nncs2)cc1)c1cnns1 +Cn1cc(CNC(=O)NCCOc2cccc(Cl)c2)cn1 +CC(C)n1nccc1NC(=O)N1CCN(c2ccccc2F)CC1 +CCN(Cc1nonc1C)S(=O)(=O)c1ccc(C(C)C)cc1 +CCNC(=O)N1CCc2nc(C)nc(N3CCOCC3)c2C1 +CCN(C(=O)c1cnc(C2CCCO2)s1)c1cccnc1 +COC(=O)C(C)(C)NC(=O)c1ccnc(Oc2ccccc2)c1 +COC(=O)N(C)c1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +Cc1cccc(OCCNC(=O)CN2CCOCC2)c1 +CNC(=O)NCC(=O)NCc1ccnc(OC2CCCCC2)c1 +CCCCNC(=O)Nc1cccc(-n2nnnc2SC)c1 +C=CCSc1nnc2n(CCCOC)c(=O)c3ccccc3n12 +CC(=O)c1cc(-c2cc3c(cc2C)OCCO3)n(C)c1C +C#CCN1CCN(C(=O)NCC(C)CN2CCOCC2)CC1 +O=C(Oc1ccc(-c2nnco2)cc1)N1CCOCC1 +O=C(Nc1cccnc1)c1cc(-n2cccc2)ccn1 +Cc1cccc(N)c1S(=O)(=O)NCc1ccco1 +CC(=O)Nc1ccccc1C(=O)N1CCN(c2ccccc2F)CC1 +CCCNC(=O)COc1nc(C)nc2onc(-c3ccc(F)cc3)c12 +CCc1ccccc1N1CC(C(=O)NC2CC2)CC1=O +Cc1ccc(NC(=O)CCN2CCOC2=O)c(C)c1 +Cc1occc1C(=O)Nc1sc(C)c(C)c1C(N)=O +CCNc1cc2c(nn1)CCN(C(=O)COc1ccc(C#N)cc1)C2 +COc1ccc(C2CCCN2C(=O)Cn2ccccc2=O)cc1OC +CC(C)(C)NC(=O)Cc1csc(-c2ccccc2)n1 +CC(Sc1nc(Cc2cccs2)n[nH]1)C(=O)NC1CCCC1 +CC(=O)c1sc(NC(=O)COc2ccccc2)nc1C +O=C(Cc1n[nH]c(=O)c2ccccc12)Nc1nc2c(s1)CCC2 +CCNC(=O)c1cc2ccccc2n1-c1ccccc1 +COc1ccccc1CNc1ncnc2sc(C)c(C)c12 +CCc1nc(C)ncc1C(=O)NCCCOc1ccccc1F +COc1cccc2cc(C(=O)Nc3cccc(-c4nncn4C)c3)oc12 +Cc1csc(NC(=O)c2cnc3scc(C)n3c2=O)n1 +COC(=O)c1ccc(CNc2ccccc2O)cc1 +CC(Oc1ccc(C#N)cc1)C(=O)NC1(C)CCCC1 +CCn1cc(CC(O)CCOc2ccccc2)cn1 +CC(C)Oc1ccc(CNC(=O)C2CCCCC2)cn1 +CCCOC(=O)c1cc(N)ccc1Sc1nc(CC)n[nH]1 +C#CCNC(=O)c1ccccc1NC(=O)C(C)NC(=O)OC(C)(C)C +CC(C)N(CC(F)(F)F)C(=O)Cc1cccc(OCC#N)c1 +CCCn1nc(C(=O)N(C)C2CCC(C)CC2)c2ccccc2c1=O +Cc1cc(Cl)ccc1NC(=O)CCc1c(C)nn(C)c1C +O=C(c1csc(Nc2ccccn2)n1)N1CCOCC1 +O=C(Nc1ccc(F)c(-n2cccc2)c1)c1cnccn1 +CCOCC(=O)OCc1cc(=O)oc2cc(C)c(Cl)cc12 +O=C(CCCNC(=O)c1ccc(F)cc1)Oc1cccc(Cl)c1 +CC(Cn1cncn1)c1nc(Cc2ccsc2)no1 +Cc1cc(C)nc(C2CCN(C(=O)CCCn3nc(C)cc3C)C2)n1 +COc1cccc(F)c1C(C)NC(=O)NC1CCCCC1O +COCCNC(=O)C(C)Oc1cccc(Cl)c1 +CCOc1ncccc1C(=O)NC(C)c1ccc2c(c1)CC(=O)N2 +CN(C)C(=O)CNC(=O)C1(c2ccc(F)cc2)CCC1 +O=C(c1ccccc1)N1CCn2c1nc1ccccc1c2=O +O=C(c1ccccn1)N1CCCC(c2noc(-c3ccccn3)n2)C1 +Cc1ccc(-c2nnn(CC(=O)Nc3nncs3)n2)cc1 +CS(=O)(=O)NCCNC(=O)CSc1ccc(F)c(F)c1 +NC(=O)CCn1ccc(NC(=O)CC2OCCc3ccsc32)n1 +Nc1cc(Br)c(N2CCCC2=O)c(Br)c1 +CC(C)N1CCN(S(=O)(=O)c2ccc3c(c2)NC(=O)CO3)CC1 +O=C(COC1CCCC1)Nc1ccc(-n2cncn2)nc1 +CCc1ccsc1C(=O)OCCN1CCCC1=O +O=C(NCCCN1CCOCC1)C1CCN(c2ccccc2)C1=O +CC(=O)Nc1ccc(NC(=O)Cc2ccc(C)s2)cc1 +Cc1ccc(NC(=O)CSc2nnc3[nH]c4ccccc4n23)cc1 +COc1cc(C)sc1C(=O)N1CCN(c2nccs2)CC1 +c1csc(CNCc2ccc(-n3cncn3)cc2)c1 +C=CCN1CC(c2nc3ccccc3n2C2CCCCC2O)CC1=O +CN1CCN(C(=O)Cc2ccccc2)CC(Cc2ccccn2)C1=O +Cc1cc(NC(=O)NCC(C)CC2(C)OCCO2)ccc1F +Cc1ccc(F)cc1C(=O)Nc1sccc1C(=O)NC1CC1 +Cc1noc(NC(=O)c2[nH]nc(C)c2Br)n1 +CCOc1cccc(C(=O)NCc2cnn(Cc3ccccc3)c2)c1 +O=C(C1CC1c1ccco1)N1CCCCC1Cn1cccn1 +COc1ccnc(NC(=O)c2cccc3c2OCO3)c1 +C=C(C)CNC(=O)c1coc(CN2CCN(c3ncccn3)CC2)n1 +COC(=O)CNC(=O)C1CC(=O)N(c2cc(Cl)ccc2C)C1 +O=C(Nc1cccc(N2CCNC2=O)c1)c1ccccc1-n1cccn1 +CC(O)CC(C)CNC(=O)NCC1(C(=O)N(C)C)CCCC1 +CCc1nc2n(n1)CCCC2NC(=O)c1cccc(NC(C)C)c1 +COc1ccc(C(=O)Nc2cc(F)ccc2Cl)cc1OC +CCS(=O)(=O)c1ccccc1N(C)CC(O)COC +CCCC(CC)n1nnnc1-c1cc(N)ccc1F +Cc1cccc(OCC(=O)Nc2cc(Cl)ccc2N)c1 +Cc1cnc(NC(=O)c2cnc3sccn3c2=O)s1 +CCOC(=O)c1cc(-c2ccc(OCC(C)C)cc2)nc(N)n1 +Cc1ncsc1CCN(C)C(=O)c1cnc2cccnn12 +Cc1noc(C)c1C(=O)Nc1cccc(Cl)c1N1CCOCC1 +COc1cc(-c2noc(CCC(N)=O)n2)cc(OC)c1OC +Cc1ccc(NC(=O)COc2ccc(Cl)cc2)cc1N +CCc1ccc(S(=O)(=O)NC2CCN(S(C)(=O)=O)CC2)cc1 +CCCN(CC(=O)NC)C(=O)c1cccc(OC)c1F +O=C(Cc1ccccc1O)N1CCCC(N2CCCC2=O)C1 +COc1ccc(C)cc1NC(=O)C12CCC(C)(C(=O)O1)C2(C)C +Cc1ccc(F)c(N2CCC(NC(=O)c3oc(C)nc3C)CC2)c1 +Cc1cc(C(=O)NCCC2CCCN(C(=O)OC(C)(C)C)C2)on1 +CN(CCNC(=O)Nc1ccccc1CC(N)=O)c1ccccc1 +Cc1ccc(C(=O)NCCOc2ccc(-c3ccco3)nn2)cc1 +COc1cc(OC)cc(C(=O)Nc2ncccc2CO)c1 +CCCC(=O)N1CCN(c2ccc3nc(NCC)sc3c2)CC1 +NC(=O)Nc1cccc(C(=O)NC2CCc3c(Cl)cccc32)c1 +CC(=O)Nc1cccc(C(=O)NC(C)c2ccco2)c1 +CC1CCC(C)(NC(=O)NCC2CN3CCCCC3CO2)CC1 +Cn1ncc2c(N3CCN(Cc4nnnn4C4CC4)CC3)ncnc21 +CN(C)c1nc(-c2cccnc2)nc2c1CCN(C(=O)C1CC1)C2 +CCOC(=O)c1ccc(OCc2cscn2)c(OC)c1 +Cc1nc(-c2ccc(NC(=O)c3cccc(F)c3)c(C)c2)no1 +COC(=O)C(CC(C)C)NC(=O)c1nc2nc(C)cc(C)n2n1 +COc1ccc(F)cc1C(C)C(C#N)N1CCCCC1 +COc1ccc2[nH]c(=O)c(CNc3cccc(C)c3C)cc2c1 +CC(NC(=O)NCCc1cnn(C)c1)C1CCCO1 +CC(=O)N1CCc2cc(NCc3cnn(-c4ccccc4)c3)ccc21 +COC(=O)CCCN1CC(C(C)C)Oc2cccc(N)c21 +Cc1nc(C(=O)NCC2CN(Cc3ccccc3)CCO2)cs1 +Cc1csc(C(=O)NCCn2ccc(C(F)(F)F)n2)c1 +CCC(Nc1ccc(NC(C)=O)c(OC)c1)c1ccccc1 +Fc1ccc(CNc2ccc3cn[nH]c3c2)c(F)c1 +CN(C)C(=O)c1cccc(NC(=O)Cc2ccc3c(c2)OCCO3)c1 +Cc1ccc2[nH]nc(C(=O)NCCCCN3CCOCC3)c2c1 +COCCC(=O)Nc1nn(-c2ccccc2Cl)cc1C +CCc1ccccc1OCC(=O)Nc1ccc(S(=O)(=O)NC)cc1 +O=C(NCc1ccccc1Br)c1cn2c(n1)COCC2 +O=C(COc1cccc(Cl)c1)NCCn1c(=O)[nH]c2cncnc21 +O=C(Cn1ncc(=O)c2ccccc21)OCCc1ccccc1 +O=C(Nn1cnc2ccccc21)c1ccccc1F +CCC(C)C(=O)Cn1nnnc1Cc1ccc(Br)cc1 +CC1(C)Cc2cc3c(cc2C(CC(N)=O)=N1)OCCO3 +CCOC1CCCN(C(=O)Nc2ccccc2CN(CC)C(C)=O)C1 +CS(=O)(=O)c1ccc(N2CCN(CCO)CC2)c(F)c1 +CCOCC1CCCN1C(=O)c1c(C)n(C)c2ccc(O)cc12 +CC1(C)C(=O)Nc2ccc(C(=O)C3CCCCN3)cc21 +CCn1cc(C(=O)Nc2cnn(CCc3ccccc3)c2)c(C)n1 +CCN(CC(=O)OC)S(=O)(=O)c1cc(C)ccc1F +CCCC1CN(C(=O)c2ccc3c(c2)CCC(=O)N3)CCO1 +COc1cc(CNC(=O)NCc2cscn2)c2ccccc2n1 +CCN(C(=O)C1CC=CC1)c1ccc(F)c(F)c1 +CCCNC(=O)CCC(=O)Nc1nc2ccc(C)cc2s1 +CCCC(=O)N1CCCC(C(=O)OCc2ccc(F)cc2)C1 +Cc1nn(C)c(C)c1CCC(=O)Nc1cnn(CC(F)(F)F)c1 +O=c1nc(SCc2ccc(Cl)cc2)c2c(n1CCO)CCC2 +CCC1Oc2ccc(N)cc2N(CC(O)CO)C1=O +O=C(CNC(=O)C1CCC1)Nc1cccc(F)c1 +CC(=O)Oc1cccc(C(=O)c2cncc(Br)c2)c1 +COc1ccc2c(c1)NC1(CCC(C)CC1)C(=O)N2CCO +Cc1nc(NC(=O)c2ccnc(N(C)C)c2)ccc1Br +CC(C)CCC(=O)Nc1ccc(CN2CCOC2=O)cc1 +COc1cc(C#N)ccc1Oc1ccnc(C#N)c1 +CCC(=O)N1CCCC(C(=O)Oc2ccc(F)cc2)C1 +CC1CCC(=O)C(C2(O)C(=O)N(C)c3ccccc32)C1 +CC1(C)C(C(=O)N2CCc3nc[nH]c3C2c2ccccn2)C1(C)C +FC(F)(F)Cn1nc(-c2ccccn2)nc1CCc1cccnc1 +COCC(=O)N(Cc1cccnc1)Cc1ccccc1OC +CC1=C(C(=O)Nc2ccccn2)C(c2cccc(O)c2)n2ncnc2N1 +O=C(NCc1ccnc(OC2CCC2)c1)N1CCOC2(CCCC2)C1 +CC(=O)c1c[nH]c(C(=O)N2CC=C(c3ccccc3)CC2)c1 +CNC(=O)c1cc(Br)c(C)c(C)c1C +Cc1cccc(NC(=O)CN(C)c2ncc(C(N)=O)cc2Cl)c1C +CC(C)c1nnc2ccc(N(C)Cc3ccccc3)nn12 +CCc1noc(C)c1NC(=O)NCc1ncc(-c2ccccc2)[nH]1 +COCCN(C)C(C#N)c1ccc(OC)c(OC)c1 +CCCn1nnc2sc3c(c2c1=O)CCC(C)C3 +N#CCCn1cc(C(=O)n2nnc3ccccc32)c(-c2ccccc2)n1 +Cc1cc(C(=O)Oc2ccc(NC(=O)C3CC3)cc2)on1 +CC1(C)CCc2cc(CC(=O)N=c3[nH]cc[nH]3)ccc2O1 +Cc1ccc(C2CC2C(=O)Nc2ccc(-c3nnco3)cc2)s1 +COC(=O)C1CC2CCC1N2C(=O)OC(C)(C)C +Cc1ccsc1C(=O)NCCNC(=O)c1ccco1 +CCOc1cc(C)ccc1CNC(=O)CNC(=O)NC +CC(=O)c1ccc(NC(=O)CCC(=O)Nc2ccccc2C)cc1 +CCOc1cc(CNc2cccc(-n3nnnc3C)c2)ccc1OC +Cc1nc(CC(=O)N(CCc2cccc(F)c2)C2CC2)cs1 +CCCNS(=O)(=O)c1cc(C(=O)NC)ccc1OC +Cc1ccc(NC(=O)N(C)CCCNC(=O)OC(C)(C)C)c(F)c1 +Cc1ccc(C(C)N(C)C(=O)NCc2ccnn2C)s1 +CC(=O)c1ccc(NC(=O)NCCCn2ccnc2)cc1 +COCc1cccc(NC(=O)Cc2c(F)cccc2F)c1 +CN(C)c1cccc(OCCN2C(=O)Cc3cc(N)ccc32)c1 +Cc1cc(C)cc(OCC(=O)Nc2cc(C)n[nH]2)c1 +CC(=O)Nc1ccc(NC(=O)c2ccc(C(F)(F)F)nc2C)cc1 +CCC(NC(=O)c1cncc(Br)c1)c1cccs1 +CCOc1cc(CO)cc2c1OC(c1ccccc1)C(=O)N2CC +CCOC(=O)c1cc(-c2cc3ccccc3o2)nn1CCO +CCCC(=O)N1CC(C(C)C)NCC1c1ccccc1 +CCC1CCC(NC(=O)CCc2c(C)nc(SC)[nH]c2=O)CC1 +COc1ccc(C(=O)NC(C(=O)Nc2ccccc2O)C(C)C)cc1 +CN(Cc1nccn1C(F)F)C(=O)C1COc2ccc(F)cc2C1 +Cc1ccc(C)c(NC(=O)C2CCCN(c3cn[nH]c(=O)c3)C2)c1 +Cc1nn2c(CO)c(-c3ccc4ccccc4c3)nc2s1 +COCCCNC(=O)c1ccc(-n2cnnn2)cc1 +O=C(c1cnccn1)N1CCN(C(=O)c2ccco2)CC1 +CCOC(=O)N1CCCC(C(=O)Nc2nc[nH]n2)C1 +CC1CCCC(N(C)C(=O)c2ccc(Cl)cc2)C1 +COc1ccc(C(=O)COC(=O)c2sccc2C)cc1OC +CNc1nnc(-c2c3c(nn(C)c2=O)CCC(C)C3)s1 +COC(=O)c1c(Br)cccc1Br +Cc1ccc(S(=O)(=O)NCCNC(=O)Nc2ccncc2)cc1 +O=C(Cn1nc2ccccn2c1=O)NCc1ccccc1-n1ccnc1 +Cn1ccnc1C(NC(=O)c1cc(F)ccc1F)c1cccc(F)c1 +Cc1cc(C)cc(C(C)NC(=O)Nc2cccc(S(N)(=O)=O)c2)c1 +Cc1ccnc2nc(C(=O)NCc3ccccc3)nn12 +CC(=O)c1cc(C(=O)Nc2cccc(C)c2C)n(C)c1 +O=C(NCc1ccco1)NCc1cccn1Cc1cccc(F)c1 +CCc1nnc(CNc2cc(Br)ccc2Cl)o1 +O=C(c1ccc(F)cc1)c1c[nH]c(C(=O)NCCCn2ccnc2)c1 +Cc1csc(N2CCCN(C(=O)CN(C)c3cnccn3)CC2)n1 +COC(=O)CN(C(C)C)S(=O)(=O)N1CCCCC1 +O=C(NCc1ccco1)c1cccc(NC(=O)c2ccncc2)c1 +CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(C#N)cc2)CC1 +OCc1nnn(-c2ccc3c(c2)OCO3)c1C1CC1 +CCOC(=O)CCC(C)NC(=O)c1cnn(C)c1C +Cc1cc(NC(=O)CS(=O)c2cccs2)no1 +OC(CN1CCN(c2nccs2)CC1)c1ccc(Cl)cc1 +CN1C(=O)COC2CN(C(=O)c3ccc(F)cc3)CC21 +CC(C)(CO)N1CCN(Cc2csc(-c3cccs3)n2)CC1 +COc1ccccc1NC(=O)CCNC(=O)c1ccn2ccsc12 +CC(C)(C)c1ccc(-n2nnc(CO)c2C2CC2)cc1 +C#CCNC(=O)Cn1cnc2sc(C)c(C)c2c1=O +Cc1cc(C)n(-c2ccc(Cl)c(C(=O)N3CCN(C)CC3)n2)n1 +CCOC(=O)C(N)c1ccccc1CN1CCOCC1 +CC(O)CN(C)C(=O)Nc1ccc(C(C)O)cc1 +COCCn1c(=O)c2c(nc(-n3nc(C)cc3C)n2C)n(C)c1=O +CCOc1cc(CNC(=O)NCCc2cccc(F)c2)ccn1 +O=C(c1ccon1)N1CCC(OCc2ccccc2F)CC1 +Cc1cccc(C)c1CNc1nc2[nH]cnc2c(=O)[nH]1 +COc1ccc(N(Cc2ccccc2)C(=O)c2ccc(=O)n(C)n2)cc1 +Cc1ccc(CC(=O)Nc2nnc(-c3cc(C)nn3C)o2)cc1 +CC1CCN(C(=O)c2cnc(C3CCCO3)s2)C(c2ccco2)C1 +NS(=O)(=O)CCNC(=O)C1CC1c1c(F)cccc1Cl +O=C(COCC12CCOC1CCN(c1ncccn1)C2)N1CCCC1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCCc1cccc(F)c1 +Cc1cnn(CC(=O)NC2CCS(=O)(=O)c3ccccc32)c1 +Cc1cc(N2CCC(CC(=O)N3CCCC3)CC2)nc(N)n1 +COCC(C)NC(=O)c1sc(-c2ccc(Cl)cc2)nc1C +CN(C(N)=O)c1ccc(OC(=O)Cc2ccc(F)c(F)c2)cc1 +CC(C(=O)Nc1cnccn1)n1nnc(-c2ccccc2)n1 +O=C(NCC1(Cc2ccccc2)CC1)c1ccc(-n2ccnn2)cc1 +COC(=O)NCC(=O)N(C)c1ccc(OC)c(OC)c1 +CN(C)C(=O)c1ccc(Cl)c(NC(=O)Nc2ccccc2)c1 +CCOc1ccc(C2NC(=O)c3ccc(Cl)cc3N2)cc1OC +CCOCC(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +Cc1noc(C)c1S(=O)(=O)N1CCc2[nH]ncc2C1 +COc1ncccc1NC(=O)CCc1nc2c([nH]1)c(=O)[nH]c(=O)n2C +Cc1ccc(C(=O)Nc2ccc(Cl)cn2)cc1F +C#CCN1CCN(C(=O)NCCOC2CCCCCC2)CC1 +Cc1ccccc1Cn1cc(NS(=O)(=O)c2c(C)noc2C)cn1 +COc1ccc2nc(SC(C)c3nc(C)no3)[nH]c2c1 +Cc1ccc(C(C)NC(=O)C2CCCN2C(=O)C(C)(C)C)o1 +Clc1ccc(-c2nnn(Cc3nc(-c4ccco4)no3)n2)cc1 +COC(=O)Nc1ccc(NC(C)c2ccccc2)cc1 +O=C(Cc1csc(-c2cccnc2)n1)NCc1ccc(F)cc1 +Cc1ccccc1CC(=O)N1CCC(c2cc(N)on2)CC1 +Cc1ccc(NC(=O)CCS(=O)(=O)c2ccc(F)cc2)cc1 +COc1cccc2c1N(CC(=O)N1CCC1)CCC2 +O=C(NC1CCCCCC1)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CCC(C)NC(=O)C(C)NCc1ccc(OC)c(F)c1 +O=C(Nc1cccnc1)C1CC12CCN(C(=O)NC1CCCCC1)C2 +CC1CCC(NC(=O)CNC(=O)COc2ccccc2)CC1 +CS(=O)(=O)N1CCCC(C(=O)N2Cc3ccccc3C2)C1 +CC(NC(=O)C(C)Sc1ccccc1)C(=O)NCc1ccccc1 +O=C(CC(F)(F)F)Nc1ccc(C(=O)N2CCCCC2)c(Cl)c1 +CCNC(=O)c1ccc(Sc2nc3ccccc3s2)nn1 +N#Cc1ccccc1NC(=O)COc1cccc(C(F)(F)F)c1 +CC(C)(C)c1nc(CNC(=O)N2CCC(C(N)=O)CC2)cs1 +Cc1ccccc1C(NC(=O)Cc1cn2ccsc2n1)C1CC1 +O=c1n(Cc2ccc(S(=O)(=O)N3CCCC3)o2)nc2ccccn12 +CCn1cc(-c2cc(NCCCc3ccc(F)cc3)nc(N)n2)cn1 +Cn1ccnc1Sc1ccccc1NC(=O)C1CC=CC1 +Cc1ccc(-c2cc(=O)[nH]c(-c3ccncc3)n2)cc1N +O=C(Nc1cnn(-c2ncccn2)c1)c1cc2ccccc2o1 +Cc1ccc2ncc(C(=O)NC3CN(C(=O)OC(C)(C)C)C3)n2c1 +CCOc1cc(CO)cc2c1OC(C)(C)C(=O)N2CC(=O)NC +Cc1c(-c2noc(C3CCCC3)n2)nnn1Cc1ccc(F)cc1 +CCCc1nc(-c2ccc3c(c2)CCCN3S(C)(=O)=O)cs1 +CCC(C)C(NC(=O)c1ccc(S(C)(=O)=O)cc1)C(N)=O +CC(C)CCN(C(=O)NC1CCN(C(=O)c2ccoc2)CC1)C1CC1 +CC(Sc1nnc(C2CC2)n1C)C(=O)N(C)Cc1ccccc1 +O=C(CC1(O)CCCC1)NCc1ccnc(OC2CCC2)c1 +CCN1CC(C(=O)NCc2ccnc(-n3cccn3)c2)CC1=O +CN(CC(=O)Oc1ccc(F)cc1)C1=NS(=O)(=O)c2ccccc21 +CCCn1ncc(C(=O)N2CCC(Oc3ccc(F)cc3)CC2)c1C +O=S(=O)(Nc1ccc2c(c1)OCCCO2)c1ccc2c(c1)CCC2 +CCc1nc(C)c(C(=O)N2CCN(C)CC2C)s1 +CCNC(=O)Cc1csc(-c2ccccc2Cl)n1 +Cn1cc(CN2CCN(c3ccccc3O)CC2)c(-c2ccncc2)n1 +Nc1cc(C(O)CNCc2ccco2)ccc1F +O=C(Nc1ccc(-n2ccnc2)nc1)Nc1cccc(C(F)(F)F)c1 +Cc1ccc(F)c(NC(=O)c2c(C)nn(-c3ccccc3)c2C)c1 +CC(Oc1ccc(Cl)c(Cl)c1)C(=O)N1CCCC1 +Cc1nc2c3ccccc3nc(SCC(=O)N3CCCC3)n2n1 +Cn1c2c(c(=O)n(C)c1=O)C(c1ccc(F)cc1)C1=C(COC1=O)N2 +O=C(Nc1ccc(N2CCOCC2)nc1)c1c(F)cccc1F +O=C(NC1CCCC1)C1CCCN(C(=O)NCc2cccs2)C1 +CCCCN(C)C(=O)CCC(O)c1ccc(C)c(C)c1 +Cc1c(N)cccc1C(=O)N1CCc2ccccc21 +O=C(Cc1cccs1)NCc1nnc2n1CCCC2 +CN(C(=O)CS(=O)c1ccc(N)cc1)C1CC1 +CN(CCc1cnn(C)c1)C(=O)COc1ccc(Cl)cc1Cl +CCC1CCCN(C(=O)Nc2c(N(C)C)ccnc2OC)C1 +NC(=O)c1ccc(C#CCNC(=O)COc2ccccc2)cc1 +O=S(=O)(c1ccc2c(c1)CCC2)N1CCN(C2CC2)CC1 +O=C(c1cnc2c(c1)CCCC2)N1CCCC2(CCCO2)CC1 +CCc1ccc(C(=O)NC(C)(C)CNC(=O)OC(C)(C)C)o1 +Cc1cc(Br)ccc1N1CCNC(C)C1=O +CC(=O)Nc1ccc(F)c(C(=O)NCc2cccc(C)n2)c1 +CC1Cc2cccc3c(=O)c(C(=O)Nc4ccc(F)cc4F)cn1c23 +COCCNC(=O)c1ccc2nnc3ncn(CCOC)c3c2c1 +CNC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(F)nc1 +COc1ccccc1CC(=O)Nc1nnc(C(C)C)s1 +COc1ccc(-c2noc(-c3ccc(O)cc3)n2)cc1OC +CCOc1ccccc1CNc1ccc(C)c(NC(C)=O)c1 +Cc1cc(C)c(OCC(=O)N(CCO)CCO)c(C)c1 +COc1ccc(-c2cc(CO)c(=O)[nH]n2)cc1C(C)C +CC1CCC(C(N)=O)CN1C(=O)Cc1ccsc1 +CC(=O)c1ccc2c(c1)N(CC(C)C)C(=O)C(C)(C)N2C +CCCCNS(=O)(=O)c1cc(S(C)(=O)=O)ccc1Cl +CC(NC(=O)c1ccco1)C(=O)Nc1ccccc1F +O=C1CC(NC(=O)N2CCOCC2)CN1Cc1ccccc1 +Cc1ccc(S(=O)(=O)Cc2ncc(CO)s2)cc1 +CN1C(Cc2cccc(O)c2)C(O)c2ccccc2S1(=O)=O +Cc1ccc(CC(=O)N2CCOCC2c2cccn2C)cn1 +CCN(C(=O)Cn1nc2n(c1=O)CCCCC2)c1ccc(C)cc1C +O=C(CCc1ccccc1O)NCC(=O)Nc1cccc(F)c1 +CC1CN(C2CC(C(C)(C)C)CCC2N)C(C)CO1 +Cn1cc(NC(=O)c2cccc3c2OCCO3)cn1 +CC1CCCCC1N(C)C(=O)CSc1nnnn1-c1ccccc1 +CN(Cc1ncnn1C)C(=O)CCCn1ccc2cc(Cl)ccc21 +CCCn1ncc(-c2ccc(OC)c(OC)c2)c(N)c1=O +CCc1[nH]c(-c2ccc3c(c2)OCCO3)nc1C#N +COc1ccc(CNS(=O)(=O)c2cccnc2)cc1OC(F)F +c1ccc(-c2nnc(CSc3cn[nH]n3)s2)cc1 +CCN(CC)C(=O)C1CCCN1C(=O)c1ccc2c(c1)OCCO2 +Cc1oc(-c2ccsc2)nc1Cn1ccnc1-c1cnccn1 +CCC(C(=O)NCc1ccc(F)c(F)c1)n1cccn1 +COCCOc1ccc(NS(=O)(=O)c2ccc(F)cc2F)cc1 +CCC(C)N(C)S(=O)(=O)c1cc(Br)cnc1NC +Nc1ccc(S(=O)(=O)NC2CCC(O)CC2)cc1 +O=C(COc1ccc(Cl)cc1Cl)NCCCCO +CCN(CC)C(=O)C1CCCN(C(=O)Nc2nc(C)ns2)C1 +Cn1cc(CCCSc2ccc(F)cc2)cn1 +COc1cc(CCNC(=O)C(NC(C)=O)C2CCCC2)ccc1C +NC(=O)c1cc(-c2ccccc2)sc1NC(=O)c1ccc(F)nc1 +COC(CNCc1ccc(NC(C)=O)cc1)c1ccccc1 +C=CCNC(=O)C1=NC(C)C(C(=O)OCC)=C1C +COc1ccccc1NCC(=O)c1ccc(F)cc1 +O=C(NCC(=O)N1CCCCCC1)c1ccsc1 +COc1cccc(C(=O)NC(C)C(=O)N2CCNCC2)c1 +COc1ccc(F)cc1C(=O)CNc1cccc(C(C)=O)c1 +O=C(NCC(=O)N1CCCC1CCc1ccccc1)C1CCCC1 +CC(C)(CNC(=O)NCc1cccnc1)c1ccc(F)cc1 +COCc1nc2cc(Cl)cnc2n1Cc1ccc(C#N)cc1 +CCOC(=O)C(C#N)c1nnc(-c2ccccc2)c(-c2ccccc2)n1 +CC(=O)Nc1cccc(NC(=O)c2n[nH]c3ccc(C)cc23)c1 +COc1ccc(C(=O)NC2CC2)cc1S(=O)(=O)NC(C)C +O=C(c1n[nH]c2ccccc12)N1CCC(O)(C(F)(F)F)C1 +CCOC(=O)C1CCCN(C(=O)c2ccc(OC(C)=O)cc2)C1 +Nc1ccc2c(c1)CCCN2C(=O)NC1CCCCC1 +COC(=O)N1CCC(NC(=O)Nc2cc(C)ccc2C)CC1 +CC(OC(=O)c1ccc(N)cc1)C(=O)Nc1ccccc1 +Cc1cc(NC(=O)c2nc(C)n(-c3ccccc3Cl)n2)[nH]n1 +O=C(NC1CC1)C1CCN(C(=O)C2Cc3ccccc3O2)CC1 +Cn1nncc1CN1CCN(Cc2ccc(Cl)cc2)C(=O)C1 +Cc1ccc(CCC(=O)OC(C)C(N)=O)cc1Cl +CC(C)NC(=O)c1ccccc1NCC(=O)Nc1ccc(F)cc1 +CCc1cc(=O)n2c(n1)SCC2CC(=O)NCc1ccccc1 +CC(C)NS(=O)(=O)c1cccc(C(=O)NCCc2ccccn2)c1 +CC(NC(=O)CCc1ccsc1)c1cccc(S(N)(=O)=O)c1 +CCn1cnnc1CNC(=O)Nc1cccc(-c2cccs2)c1 +Cn1cc(CC2C(N3CCOCC3)CCN2C(=O)c2ccco2)cn1 +C=CCOC(C)C(=O)NC1CCCc2c1cnn2C +Cc1cc(C)nc(N2CCN(Cc3cccnc3)CC2)n1 +O=C(Nc1ccccc1)c1cn(-c2cccc(Br)c2)nn1 +CC(O)(CNC(=O)COc1ccc(Cl)cc1Cl)c1ccco1 +CC(=O)c1ccc(NC(=O)C2COc3ccccc3C2)cc1 +CCc1ccc(C(=O)N(C)Cc2cnn(Cc3ccccc3)c2)cc1 +COc1ccccc1OC1CN(C(=O)c2ccccc2C(C)=O)C1 +CCc1nc2n(n1)CCCC2NC(=O)CCc1ccc(C)cc1 +COC(=O)Cc1c(C)c2cc3c(cc2oc1=O)OCO3 +CCOC(=O)c1cnn(C)c1NC(=O)COc1ccccc1F +CC(C)c1ccccc1NC(=O)CSc1ncccn1 +COC(=O)c1ccc(NC(=O)C(C)OCC(F)(F)F)cc1 +Cc1ccc(NCC(=O)N(C)C)cc1-n1cnnn1 +O=C(CCNC(=O)c1cnc2cccnn2c1=O)Nc1nccs1 +O=C(Nc1nccs1)c1nn(-c2ccccc2)c2c1CCC2 +Cc1ccc(S(=O)(=O)CCCCC#N)c(C)c1 +N#Cc1ccc(N2CCC(OCCc3ccccc3)CC2)nc1 +O=C(CC1C=CCC1)NCc1cc(Cl)c2c(c1)OCCCO2 +CCN1C(=O)c2cccc3c(NC(=O)c4ccco4)ccc1c23 +N#Cc1cc(F)ccc1CN1CCOCC1C1CC1 +Cn1cc(CNC(=O)c2ccc3c(c2)CCC(=O)N3)cn1 +CC(C)(C)OC(=O)N1CC(C#N)C(NCc2cccnc2)C1 +Cc1cc(C)cc(NC(=O)c2cc(F)ccc2N)c1 +CCN(C(=O)c1ccc2c(c1)OCCO2)c1cccc(F)c1 +Cc1ccc(CC(C)NC(=O)N(C)C(C)C)s1 +COc1cc(OC)c(OC)cc1CNC(=O)CC1CCCCC1 +CC(C)CCC(=O)N1CCN(C(=O)NCCCn2cccn2)CC1 +Cn1cc(C2CC2C(=O)Nc2ccc(=O)n(C)c2)cn1 +O=C(NCCc1ccc(F)cc1)c1ccc2c(c1)CNCC2 +Nc1ccc2c(c1)N(C(=O)C1CCCC1)CCS2 +O=C(Nc1cnn(CCc2ccccc2)c1)C1CCC1 +Cc1cc(C)c2c(c1)N(CC(=O)NC1CCOCC1)CCC2 +Cc1cc(C)n(CCC(=O)NCCc2ccc(-n3cccn3)cc2)n1 +COc1ccccc1CNC(=O)c1ccccc1N +CCCn1ncc(C(=O)N2CCC(C(F)(F)F)CC2)c1C +CSc1ccc(C(C)NC(=O)c2cccc3cn[nH]c23)cc1 +CCOc1cc(C)nc(N2CCN(C(=O)c3ccnc(C)n3)CC2)n1 +CC(C)c1nn(-c2cccc(F)c2)c2c1CNCC2 +Cc1sc2nc(SCC(=O)N3CCCC3)n(C)c(=O)c2c1C +CCOC(=O)c1cc(C#N)c(SC)nc1-c1ccccc1 +O=C(NC1CCN(c2ccccc2)CC1)c1cnns1 +CCC(C)c1ccc(C(CC)NC(=O)C2CCCO2)cc1 +FC(F)(F)c1ccccc1NCc1nnc(-c2ccccc2)o1 +NC(=O)c1ccccc1NC(=O)CC1CCCCC1 +FC(F)(F)COc1ccccc1Oc1ccc2nnnn2n1 +COc1ccccc1CSc1nnc(-c2ccco2)n1C +CC(C)CCCNC(=O)Nc1cccn(Cc2ccccc2)c1=O +CC(C)CNC(=O)NCc1cccc(OCC(F)(F)F)c1 +Nc1n[nH]c2nc(C3CCCCC3)c3c(c12)CCC3 +CC(=O)Nc1cccc(NCc2ccccc2OCC(=O)N(C)C)c1 +CC(C)n1cc(S(=O)(=O)Nc2cnn(C)c2)cn1 +CCCOc1cccc(CNC(=O)c2csnn2)c1 +O=C(Nc1ccccc1-n1cccn1)c1cc(-c2ccco2)on1 +CC(C)CNC(=O)c1n[nH]c2cccc(Cl)c12 +O=C(CCCc1cc(F)ccc1F)NCC(=O)N1CCCC1 +CNC(=O)c1cccc(OS(=O)(=O)c2ccc(C)cc2C)c1 +Fc1ccc(Cc2nn3c(-c4ccco4)nnc3s2)cc1 +COC(=O)Cn1c(C)cc(=O)n2nc(-c3ccccc3)nc12 +COc1ccc2[nH]cc(CCNc3nc(C)nc4ncccc34)c2c1 +COc1ccc(OC)c(NC(=O)CCC(C)O)c1 +COc1ccccc1CC(=O)Nc1cccc(NC(C)=O)c1C +Cc1nc2ccccc2n(CC(=O)Nc2ccc3cc[nH]c3c2)c1=O +COC(=O)C(NC(=O)N1CCC(C(N)=O)CC1)C(C)C +N#CCCN(CCC#N)CC(=O)Nc1ccccc1 +CCOC(=O)CCn1c(=O)oc2ccc(CO)cc21 +NC(=O)c1ccc(SC2CCCCC2)c(N)c1 +COc1ccc(NC(=O)CCC(=O)c2ccc(F)c(F)c2)cc1OC +COCc1cc(=O)[nH]c(Nc2ccc(C)c(F)c2)n1 +Cn1cc(C(=O)OCC(=O)NCc2cccs2)c2ccccc21 +O=C(c1ccncc1)N1CCOC2C(OCc3ccccn3)CCC21 +CN(C)C(=O)CN1CCN(CCOc2ccc(Cl)cc2)CC1 +Cc1ccc2c(c1)N(Cc1ccccc1Cl)C=NS2(=O)=O +CN(C)c1nc(COc2cc(F)cc(F)c2)ns1 +CC(C)OC(=O)c1cc(-c2ccc3c(c2)OCCO3)nn1CCO +COC(=O)c1cccc(NS(=O)(=O)c2cccc(C(C)=O)c2)c1 +CCCC(C)N1CC2(CCN(C(=O)c3cnc(C)cn3)CC2)OC1=O +CC(C)n1cnc2cc(CCCn3cc(N)cn3)ccc21 +COc1ccc(C(=O)NCCNC(=O)c2ccco2)c(O)c1 +CCOC(=O)c1nn(Cc2ccccc2F)c(N)c1C +CN(C)S(=O)(=O)c1cccc(C(=O)Nc2ccc3c(c2)CCC3)c1 +Cc1ccccc1SC(C(=O)NCc1cccnc1)C(C)C +Cn1nc(CNC(=O)c2ccncc2)cc1-c1ccccn1 +CCCC(=O)Nc1cccc(NCC(=O)Nc2cc(C)nn2C)c1 +Cc1ncc(-c2ccncc2)c(CN(C)C(=O)C2CC2)n1 +COc1ccc(CNC(=O)Cc2cc(Cl)c3c(c2)OCCO3)cn1 +CC(C)NC(=O)C(NC(=O)c1c(C(C)C)nn2ccccc12)C(C)C +CCCNC(=O)Cc1cc(-c2ccc3c(c2)OCCO3)on1 +COC(=O)c1ccc(OCC(=O)NCc2cccc(Cl)c2)cc1 +CCOc1ccccc1CNc1ccccc1CO +COc1ccc(NC(=O)C(OC)c2ccccc2)c(OC)c1 +N#CCC1CCCc2[nH]nc(-c3cccc(N)c3)c21 +COC(=O)CCc1cc(Cl)c(Cl)c2ccncc12 +CCCNC(=O)CNS(=O)(=O)c1cc(C)c(OC)cc1C +CC(C)(CNC(=O)NC1CCCc2ccccc21)N1CCOCC1 +CC(C)(C)c1nnc(NC(=O)Nn2cnnc2)s1 +CCOC1CCN(C(=O)NC(C)Cc2cccc(OC)c2)CC1 +Cc1cccc(CC(=O)OCC(=O)N(C)c2ccccc2)c1 +CN(C(=O)c1cc(C(F)(F)F)ccc1F)c1cnn(C)c1 +Cn1ncc2c(=O)[nH]c(CN3CCN(c4cnccn4)CC3)nc21 +COc1ccccc1NC(=O)C1CCCN(S(=O)(=O)N(C)C)C1 +COc1ccccc1CNC(=O)COc1cccc(C(=O)N(C)C)c1 +CC(C)CNC(=O)Cc1n[nH]c2c(Cl)cccc12 +COc1ccccc1C(C)N(C)C(=O)CCn1c(C)csc1=O +CCC1(O)CCN(C(=O)c2cnn(C)c2-n2c(C)ccc2C)CC1 +Fc1cccc(Cn2nc(C(F)(F)F)c3cnccc32)c1 +CC1(C)C2CCC1(CS(=O)(=O)NCCC1=CCCCC1)C(=O)C2 +Cc1ccccc1-c1nnn(CC(=O)c2ccc(F)cc2F)n1 +COc1cccc(-c2noc(CNc3ccccc3C(C)=O)n2)c1 +COc1ccccc1Cn1c(CNC(=O)C(C)C)nc2ccccc21 +Cc1cc(C(C)C(=O)N2CCN(CCO)CC2)c(C)o1 +O=C(Nc1ccncc1)c1cccnc1OCC(F)F +CC(=O)Nc1cc(C(=O)OCC2CC=CCC2)ccc1C +Cc1c(C(=O)Nc2cc(F)ccc2F)oc2c1-c1[nH]ncc1CC2 +CC(=O)c1cccc(NCc2ccc(O)c(F)c2)c1 +COc1ccc(C2(CNS(N)(=O)=O)CCCCC2)cc1 +COc1ccc(NC(=O)COc2ccc3c(c2)OCO3)cc1Cl +O=C(Nc1cccnc1)OCCNC(=O)c1cccnc1 +COC1CCN(C(=O)Cc2ccccn2)C1Cc1ccncc1 +CC1(C)CCN(C(=O)NCC(C)(C)c2ccncc2)C1 +Cn1c(=O)ccn(CC(=O)C(C#N)c2nc3ccccc3[nH]2)c1=O +Cc1ccc(Cn2nccc2NC(=O)CCOC(C)C)o1 +CN(C)C(=O)c1ccc(CN2CCCC3(C2)OCCO3)cc1 +Cc1nc(N)cc(-c2ccc(-c3ccccc3)cc2)n1 +O=C(COc1ccccc1F)Nc1ccc(O)cc1 +COc1ccc(C(C#N)CN2CCOCC2)c(OC)c1 +O=C(Nc1ccccc1N1CCOCC1)c1ccc(Cl)cc1F +Cc1cccc(C)c1NC(=O)CNC(=O)CN(C)c1ccccc1 +COc1ccc(C2CC23N=C(c2ccccc2)OC3=O)cc1OC +O=c1[nH]c2ccc(Nc3nccc(C(F)(F)F)n3)cc2[nH]1 +Cc1cccc(NC(=O)Cn2nc(C)ccc2=O)c1 +CCC1CCC(NC(=O)CCc2nc(-c3ccco3)no2)CC1 +CCOC(=O)c1cccc(C(=O)Nc2nc3ccc(C)cc3s2)n1 +O=C(c1cccc(-n2ccnc2)c1)N1CCCCCC1c1ccco1 +Cc1nc(C(C)N(C)Cc2cnc(N3CCCC3)nc2)c(C)s1 +C#CCN1CCN(C(=O)NCC2(C)CCCC2)CC1 +CCOC(=O)c1sc(-c2cccs2)cc1N +COCCn1ccc2cc(C(=O)Nc3ccn(C)n3)ccc21 +Cn1cccc1C1COCCN1C(=O)CCc1ccccc1 +Cc1ccc(CNC(=O)c2nn(C)c3ccc(F)cc3c2=O)o1 +COCc1nc2ccccc2n1CC(O)COc1c(C)cccc1C +Cc1cc(O)c2c(=O)c(-c3csc(C)n3)c(C)oc2c1 +O=C(CC1CCCCCC1)N1CCC(n2cc(CCO)nn2)CC1 +CCC(=O)Nc1ccc(OC(=O)c2ccco2)cc1 +O=C(NCCCOc1cccc2cccnc12)c1ccc[nH]1 +O=C(NC1CCCN(c2cccnc2)C1=O)c1cccc(F)c1F +CCC(C)NC(=O)CSc1nnc(-c2ccco2)n1N +CCc1ccc(C(=O)Nc2ccc(F)c(C#N)c2)o1 +CCC(C)n1ncc(C(=O)N2CCC3(CCCC3)C2)c1C1CC1 +COc1ccc(CNC(=O)N2CCOCC2C2CC2)cc1C +Cc1csc(C(C)(C)NC(=O)Nc2cnn(CC(F)F)c2)n1 +Cc1ccc(C(=O)CCCC(=O)NC2CCCC2)cc1 +O=C(CCc1ccccc1O)NCc1ccc(-n2ccnc2)cc1 +Cc1ccc(-n2cnc(C(=O)NCc3cccc(F)c3)n2)cc1 +Cc1ccc(CNC(=O)N2CCOC(C)(C)C2)c(C)c1 +CC(=O)NC(CC(=O)Nc1ccc2ccccc2c1)c1ccccc1 +COc1ccc(C(=O)N=c2[nH]nc3ccccn23)c(C)c1 +O=C(CCCn1c(=O)c2cccn2c2ccccc21)NCc1ccco1 +C#CCN1CCN(Cc2nn(-c3ccccc3)c3c2CCC3)CC1 +CC(CCc1ccccc1)NC(=O)c1ccncc1F +O=C(CCNC(=O)c1ccco1)NCC1CN2CCCCC2CO1 +Cc1ccc(C)c(N2CCN(c3nnnn3-c3ccccc3)CC2)c1 +CCc1c(C)nc2n(c1=O)C(CC(=O)NCc1ccco1)CS2 +COc1cc(C)c(Cl)cc1S(=O)(=O)NCc1ccncc1 +O=C(Nc1ccccc1Cl)C1CCCN(C(=O)NC2CC2)C1 +CCC(C)C(=O)NCC(=O)NCc1nncn1CC +CN(Cc1cnn(C)c1)C(=O)c1cc(F)c(Cl)cc1Cl +CC(C)(C)c1noc(CCC(=O)NCc2ccc3c(c2)OCCO3)n1 +O=C(NCCCOCC(F)(F)F)c1cc(Cl)c[nH]1 +Cc1csc(NC(=O)CSc2nc3ccccc3c(=O)[nH]2)n1 +CC1COCCN1Cc1coc(-c2ccccc2)n1 +Cc1c(C(=O)N2CCCC(n3cncn3)C2)cnn1C +COc1ccc(NC(C)=O)cc1NC(=O)NC(C)(C)CC(C)(C)C +CCn1ccc(C2C(C(N)=O)=C(C)Nc3ncnn32)n1 +O=C(COc1ccccc1)NCC(=O)c1ccc2c(c1)OCO2 +O=C(CCc1cccnc1)N1CCCC1c1nc2ccccc2s1 +CNC(=O)c1cccc(NCC(=O)NC(C)C(C)C)c1C +CC(C)OC(=O)c1cccnc1-c1ncccc1C(=O)OC(C)C +O=C(NCCNc1cnccn1)c1ccc(Br)cc1O +CCN(CC)c1ncnc(Nc2cc(OC)ccc2OC)c1N +COCCOc1nc(C(C)C)nc(NC2CC2)c1N +CC(=O)N1CCN(c2cccc3cccnc23)CC1 +Cc1nnc(C(C)N(C)CCc2ccc(Br)cc2)o1 +Cc1ccc(C(C)N(C)C(=O)c2ccc(=O)n(C)n2)cc1 +CC(Cn1cccn1)n1cnc2sc3c(c2c1=O)CCCCC3 +COc1ccc(OC)c(C2CCCN2C(=O)C2CCCC2)c1 +COc1cccc(C(=O)CSc2nc3ccc(N)cc3s2)c1 +COc1ccc(-c2cnc(Cn3nc(C(N)=O)ccc3=O)o2)cc1 +CC(=O)NCC1NCCc2ccc(C(C)(C)C)cc21 +Cc1ccc(S(=O)(=O)N(C)c2ccc(F)c(N)c2)cc1C +Cc1cnn(C2CCCN(C(=O)c3cc(-c4ccccc4C)n[nH]3)C2)c1 +CN(Cc1ccccc1)C(=O)Cn1ccc2ncccc2c1=O +CCOC(=O)c1cc2cc(NCc3noc(C)n3)ccc2s1 +Cc1ccn(CC(=O)Nc2cccc(C(=O)N(C)C)c2)c(=O)c1 +Cc1ccc(Cl)cc1-c1cccn2nc(N)nc12 +O=C(Nc1nc(-c2ccc3c(c2)OCO3)cs1)C1CCOCC1 +COc1ccccc1CNC(=O)c1cc(C)nc2c1c(=O)[nH]n2C +Cc1cc(C)c(C(=O)N2CCC(OCC3CCCO3)CC2)c(C)c1 +CS(=O)(=O)c1cc(C(=O)Nc2ccc(F)cc2F)ccc1Cl +C#CCN1CCN(C(=O)NC(C)c2ccc(C)c(F)c2)CC1 +CCCCNC(=O)COC(=O)c1sccc1C +O=C(c1ccc2c(c1)CCO2)N1CCC(COc2ccccc2)CC1 +CCN(Cc1cccc(F)c1)C(=O)C1CCC(=O)N1 +CC(C)(C)C(=O)N1CCN(Cc2noc(-c3ccc(F)cc3)n2)CC1 +CCC(C)Nc1ncnc(Nc2ccc(C)cn2)c1N +CC(C)c1cc(C(=O)N2CCCCCC2)nc(N2CCOCC2)n1 +c1cn(Cc2cn3ccsc3n2)c(-c2nc3c(s2)CCCC3)n1 +CCCN(CC(F)(F)F)c1nc(C)c(CO)s1 +Cc1n[nH]c(SC(C)C(=O)N2CCCc3ccccc32)n1 +Cc1ccc(Cl)cc1NC(=O)C(c1ccccc1)n1cnnn1 +CCOc1ccc(NC(=O)CC(C#N)c2cccs2)cc1 +COC(=O)c1cccc(NC(=O)Cc2ccc(C)s2)c1 +N#CCc1ccc(NC(=O)c2cc(Cl)c[nH]2)cc1 +CNc1cc(-c2cc(OC)cc(OC)c2)c2cc[nH]c2n1 +CC(Oc1ccc2c(c1)OCO2)C(=O)Nc1ccc2c(c1)OCCO2 +Cn1c(=O)oc2cc(NC(=O)NCCC(=O)NC3CCCC3)ccc21 +c1ccc2oc(N3CCOC(Cn4cncn4)C3)nc2c1 +CCCOc1ccc2c(c1OC)C(C1CCCO1)NCC2 +c1csc(-c2csc3ncn4cnnc4c23)c1 +COCCn1cnnc1SCc1ccc(C)cc1 +CC(C)C(=O)N1CCc2cc(C(=O)C(C)N)ccc21 +Cc1cc(OC(=O)c2ccc(C)c(C)c2)n2ncnc2n1 +CN(C)c1ccc(Cl)cc1NC(=O)NCc1cccc(C#N)c1 +CCc1noc(-c2cccc(OCC(=O)Nc3ccc(F)cc3)c2)n1 +CCNC(=O)Nc1ccc2c(c1)C(=O)N(C)CCO2 +CCOc1ccccc1CNC(=O)CCc1cccnc1 +CCc1noc(CN2CCN(C(=O)c3ccccn3)CC2)n1 +Cc1cc(C(=O)NCCOc2cccc(F)c2)on1 +COc1cc(CNC(=O)c2ccc3c(c2)CCC(=O)N3)ccn1 +O=c1[nH]c(-c2cnccn2)nc2c1CN(Cc1ccccn1)CC2 +O=C(Cc1cccc(F)c1F)NCc1ccccc1Cn1cccn1 +O=C(CN1C(=O)COc2ccccc21)N1CCc2ccccc2C1 +CCS(=O)(=O)c1ccc(NC(=O)N(C)C(C)CC#N)cc1 +CC=Cc1ccc(OCC(=O)Nc2ncc(C)s2)c(OC)c1 +CCOc1cc(NC(=O)COc2ccc(C)cc2)ccc1OC +CNC(=O)CCC(C#N)c1ccc(Cl)c(Cl)c1 +Cc1ccsc1C(=O)NC(C)C(=O)NC(C)(C)C +Nc1ccc(NC(=O)CCCc2cccs2)nc1 +Cc1noc(C)c1NC(=O)NCCOc1ncccc1Cl +CC1COC2(N=C(N)C3(C#N)C(c4ccccc4F)C23C#N)O1 +O=C(Cc1cccnc1)NC1CCN(c2ccc(F)c(Cl)c2)C1=O +COc1ccc(NC(=O)c2ccc(C)cc2)cc1-n1nnnc1C +COC(=O)c1c(NC(=O)c2cccs2)sc(C(N)=O)c1C +COC(=O)c1ccc(COc2ccc(NC(=O)c3ccco3)cc2)o1 +COc1ccc(OC2CCN(C(=O)c3ccncc3)CC2)cc1 +O=C(C1CCOc2ccccc2C1)N1CCN(C2CCCC2)C(=O)C1 +CCn1cc(CN2CCCCC2C2OCCO2)cn1 +CCn1cc(NC(=O)c2cnc(Cc3ccc(F)cc3)s2)cn1 +Cn1nc2n(c1=O)CCN(Cc1cc(F)cc3cccnc13)C2 +O=C1C(Nc2ncc(Cl)cc2F)CCN1C1CCOCC1 +O=C(OCC1CCOc2ccccc21)c1cocn1 +Cc1nc(COC(=O)c2ccc(CCNC(N)=O)cc2)sc1C +CC(C)(C)OC(=O)c1ccnc(N2CCOCC2)c1 +Cc1nc[nH]c1-c1nccn1CCc1csc(-c2ncccn2)n1 +Cc1n[nH]c(SCc2ccc(F)cc2Cl)n1 +O=C(Nc1ccccc1C(=O)N1CCCCC1)N1CCCCCC1 +O=C(CCCc1cccs1)N1CCn2c1nc1ccccc12 +C=CCSc1nc(N)c(C(=O)Nc2cccc(F)c2)cc1C#N +COc1ccccc1C(C)N(C)C(=O)NCCNc1cnccn1 +O=C(CSc1nc2ccccc2o1)NCc1cccnc1 +CC(C)c1ccc(OCC(=O)Nc2ccc(-n3cnnn3)cc2)cc1 +CCc1sc(C(=O)Nc2cccc(-n3cnnn3)c2)cc1C +CC1(C)OCC2(CO1)CN(C(=O)c1ccccc1Br)C2 +CCOc1ccc(-c2cc(C)n3nc(C(N)=O)cc3n2)cc1 +O=C(NCCc1cccs1)c1ccnc(-n2cncn2)c1 +Cc1ccc(C)c(NC(=O)CCn2c(=O)oc3ccccc32)c1 +Cc1cc2ncc(C(=O)NC3CCCCC3)c(C)n2n1 +CCCN(CC(=O)NC)C(=O)c1nc(-c2ccccc2)oc1C1CC1 +N#Cc1nnn(CCO)c1CCOc1ccccc1 +CC(Nc1cccc2cccnc12)c1cccc(O)c1 +CCCC(=O)NCC(=O)N1CCCCCC1c1ccncc1 +Cn1ccnc1C(=O)NC1CCN(c2ccccc2Br)C1 +O=C(C1CC1)N1CCCC1CS(=O)(=O)c1ccccc1 +COc1ccc(C(=O)N(C)C(C#N)CC(C)C)cc1OC +CN(Cc1ccccc1F)S(=O)(=O)c1ccc(N)cc1 +O=C(Cn1nnc(-c2ccccc2)n1)Nn1cnc2ccccc2c1=O +Cc1cc(CNC(=O)NCC(O)c2cccc(F)c2)no1 +CCCOc1ccc(-c2ncc(C(=O)OCC)c(N)n2)cc1 +CC(=O)Nc1cccc(Nc2nc(C)nc3c2CCC3)c1 +COc1ccc(C2=CCN(CC(C#N)CCC#N)CC2)cc1 +Nc1ccc(S(=O)(=O)Nc2ncc(Cl)cn2)cc1 +Cc1cc(C(=O)N(C)Cc2nccn2C(F)F)on1 +CC(C)(C)CCCNC(=O)N1CCOCC1C1CC1 +CCCc1ccc(OC(=O)c2cc(C(N)=O)cn2C)cc1 +OC(COCc1cccs1)Cn1nnc(-c2ccccc2)n1 +CN(CC1CCCO1)C(=O)c1ccc2c(=O)n(C)c(=O)n(C)c2n1 +O=C(c1ccccc1)C1CCN(C(=O)c2ccc3[nH]nnc3c2)CC1 +Nc1ccc(S(=O)(=O)NCCOCCO)nc1 +Fc1ccc(C#CCN2CCN(Cc3ccncc3)CC2)cc1 +CC(=O)c1cccc(S(=O)(=O)NC(C(N)=O)C(C)C)c1 +Cc1ccnc(NC(=O)CCN2C(=O)CCc3ccccc32)c1 +Nc1cnn(CCc2ccc(Br)cc2)c1 +CC(C)N(Cc1ccccc1)C(=O)CS(=O)(=O)c1ccccc1F +Cc1ccc(NC(=O)c2cncn2-c2ccccc2)cc1F +O=C(Cn1nc2ccccn2c1=O)Nc1ccc(F)cc1Cl +Cc1ccccc1-n1c(N)cc(=O)n(CCc2ccccc2)c1=O +CCCN(CC(=O)OC)C(=O)c1cc(Br)cn1C +c1cncc(-c2nc(N3CCOCC3)ncc2-c2ccsc2)c1 +CN(Cc1ncc(-c2ccccc2)o1)S(=O)(=O)c1ccccc1F +Cc1ccc(=O)n(CCc2ccc3c(c2)CCO3)n1 +Cc1cc2ccccc2n1CC(=O)NC(C)c1ccncc1 +COC(=O)C(C)Cc1ccc(NC(=O)c2ccc[nH]2)cc1 +CCSc1cc(C(=O)NC(C(N)=O)C(C)CC)ccn1 +O=C(COC(=O)c1ccnn1C(F)F)NC1CCCCC1 +CC(C)(Oc1cccc(Cl)c1)C(=O)N1CCC(n2cncn2)CC1 +CN(CC1CC1)C(=O)Nc1cc(-c2ccccc2)on1 +O=S(=O)(Cc1ccccc1Cl)NCC1CCCO1 +CC1OCCN(C(=O)NC2CCN(c3ccc(C#N)cc3)CC2)C1C +O=C(c1cccnc1)c1conc1C(=O)c1ccc(Cl)cc1 +O=C(Nc1ncnc2sc3c(c12)CCC3)c1ccco1 +Cc1nc(CN2CCN(Cc3cncs3)CC2)oc1C +CC(NC(=O)Nc1ccc(Br)cc1)c1ccccn1 +CC(=O)NC(C(=O)N1CCCC(n2nc(C)cc2C)C1)C1CCCC1 +CCCC(C)N1CC(C(=O)Nc2ccc3oc(=O)[nH]c3c2)CC1=O +Cc1cc(C(=O)Nc2nc3c(F)cccc3s2)n(C)n1 +CN(CC1CC1)C(=O)CCNC(=O)NC1CCCCC1 +O=C(NCc1cccnc1OC1CCCC1)c1ccc[nH]c1=O +COCc1ccccc1NC(=O)c1cc(C)n(C2CC2)c1C +COc1cc(CNC(=O)c2cccnc2OC)cc(OC)c1OC +CN1CC2(CCN(C(=O)c3cccn(C)c3=O)CC2)CC1=O +CSc1ccc(NC2C(=O)Nc3ccc(F)cc32)cc1 +COC(=O)C(CNC(=O)c1ccc(F)cc1)Oc1ccc(F)cc1 +COC(=O)c1sc(NC(=O)c2cccc(C(F)(F)F)c2)nc1C +O=S(=O)(c1cccc(F)c1)N1CCN(CC(F)(F)F)CC1 +CCc1[nH]c(C(=O)Nc2ncc(C)s2)c(C)c1C(=O)OC +CCC(C)n1nccc1NC(=O)C(C)N(C)Cc1ccc(C#N)cc1 +Cc1ccccc1C(CC(=O)Nc1nnc(C(C)C)s1)NC(N)=O +CC(NC(=O)Cc1csc(-c2ccccc2)n1)c1ccncc1 +Cc1cc2c(cc1C)N(CC(N)=O)C(=O)C=C(c1cccs1)N2 +O=C(NCCc1c[nH]c2cc(F)ccc12)NCc1ccccc1 +CN(C)C(=O)N1CCCC(C(=O)NCCc2ccccc2)C1 +Cc1cccc(NC(=O)C2CCN(c3nc(C)cc(C)n3)CC2)n1 +CN(C)C(=O)Cc1ccc(NC(=O)c2ccncc2F)cc1 +Cc1noc(C)c1CNC(=O)C1CCC(NS(=O)(=O)C2CC2)C1 +Cn1ccc(NS(=O)(=O)c2cnc(N)nc2)n1 +CCCn1c(SCC(=O)c2ccc3c(c2)CCC3)n[nH]c1=O +COCCOc1ccccc1NC(=O)c1cc(-c2ccccc2)no1 +COc1ccc(C(=O)Oc2c(C)ccc(C)c2C)nn1 +CC(C)C(C)(C#N)NC(=O)COC(=O)c1ccc(O)cc1 +CNC(=O)Cc1ccc(NC(=O)CSc2ccncc2)cc1 +C#CCN1CCN(C(=O)NCCCNC(=O)c2ccc(F)cc2)CC1 +CCS(=O)(=O)c1ccc(NC(=O)N(C)CCOC)cc1 +CC(NC(=O)c1ccccc1NC(=O)c1ccccc1)c1ccncc1 +Cc1ccc2cc(C(=O)N3CCCC(O)C3)[nH]c2c1 +O=C(NCCc1c[nH]c2ccccc12)c1cccc2c1OCCO2 +Cc1ccsc1C(=O)Nc1nc2ccccc2n1C +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)N1CCC(C)(O)C(C)C1 +CCOc1ccccc1NCC(=O)N1CCCCC1 +COc1ccc(C(=O)OCc2cnc(-c3ccccc3)s2)nn1 +COc1cc(C)c(C(=O)N2CCc3ccccc3CC2)cc1OC +Cc1noc(C)c1CCC(=O)N1CCN(CCc2ccccn2)CC1 +Brc1cccc2c1-c1n[nH]cc1CN2 +CN(C)C(=O)C1CCCN(C(=O)c2cnc(C3CCCO3)s2)C1 +CCCC(=O)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1 +CCc1nc(Cn2cnc3c(cnn3-c3ccccc3C)c2=O)no1 +CCc1cc(C(=O)Nc2cc(F)ccc2F)cs1 +Cc1ccc(C(O)CCCC(=O)N2CCC(C)CC2)cc1 +CCN(CC(C)C)c1c(C#N)c(=O)n(C)c(=O)n1C +O=S(=O)(c1cccc(S(=O)(=O)N2CCCC2)c1)N1CCCC1 +Cc1ccc(C(O)(CC(=O)NCC2(C)CCCO2)C(F)(F)F)o1 +CC(=O)Nc1cccc(C(=O)N(Cc2cccc(Cl)c2)C(C)C)c1 +CC(O)(CNC(=O)C1(c2ccc(F)cc2)CC1)c1cccs1 +CC1CCC(CCC(=O)Nc2ccn(-c3ncccc3Cl)n2)O1 +N#Cc1cccnc1NCCNC(=O)NCc1ccc2c(c1)OCO2 +COc1cc(CC(=O)NCc2cccs2)cc(OC)c1OC +CC(C)C(=O)NCCNC(=O)c1ccccc1Cc1ccccc1 +CS(=O)(=O)c1ccc(C(=O)Nc2ccc3c(c2)OCO3)cc1 +Cc1noc(C2CCCN2C(=O)c2cccnc2)n1 +CC1CCc2c(sc(NC(=O)CSc3n[nH]c(N)n3)c2C#N)C1 +COCCCn1ccc2c(C(=O)OC)c(C)nc(C)c2c1=O +Cc1cc(CCNC(=O)CCc2c(C)noc2C)on1 +CN(CCOCC1CC1)C(=O)Nc1ccc2[nH]ccc2c1 +CCN(CC1CCCO1)c1ncc(C(C)=O)s1 +CCC(C)(C)C(=O)Nc1ccccc1C#CCCO +O=C(Cc1csc(-c2ccoc2)n1)Nc1nc2ccc(F)cn2n1 +NC(C(=O)NCc1ccco1)c1ccc(O)c(F)c1 +O=C(NCCCN1CCOCC1)c1cc(Cl)c2c(c1)OCCO2 +Cc1nc2ccccn2c(=O)c1NC(=O)c1cccc(F)c1 +Cc1nc2n(c(=O)c1C)C(CC(=O)N1CCCC(C)C1)CS2 +CCn1nc(C)c(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)c1C +Cc1ccc(S(=O)(=O)N(CCO)CC(C)O)cc1 +CC(NC(=O)c1ccnc(-n2cnnc2)c1)c1ccc2c(c1)CCCC2 +CCn1ccc(NC(=O)CCc2c(C)nn(C)c2C)n1 +CC(C)c1ccc(-n2ccnc2SCC(=O)NCC(N)=O)cc1 +CCOC(=O)N1CCN(C(=O)Nc2cccc(Cl)c2C)CC1 +O=C(Cn1c(=O)oc2ccccc21)Oc1ccc(Br)cc1 +CCc1cc(C#N)c(NC(=O)c2ccc(CNC(C)=O)cc2)s1 +CCOC(=O)C(C)Sc1nnc2n1CCN2c1ccccc1 +COCCNC(=O)C(C)Oc1cc(C)ccc1C +CCCCN(Cc1ccccc1)c1ncnc2c1cnn2C +CC(OCC1CCCO1)C(=O)Oc1ccc(N2CCOC2=O)cc1 +Cc1ccccc1S(=O)(=O)CC(=O)Nc1ccc(Cl)cc1 +CC(NC(=O)N(C)Cc1ccccc1N1CCOCC1)c1ccco1 +Cc1ccccc1C(=O)NCC(=O)Nc1c(C)cccc1C +CS(=O)(=O)c1ccc(NC2CCCC2)c(N)c1 +N#Cc1cccc(NC(=O)NC2CCN(S(=O)(=O)C3CC3)CC2)c1 +Cc1cc(C(=O)NC(c2ccccc2)C(F)(F)F)no1 +Oc1ccccc1SCc1nc2ccccc2[nH]1 +O=c1[nH]ncc(NCc2ccc(OCC(F)(F)F)nc2)c1Cl +NC(=O)C1CCN(C(=O)c2cc3c(Cl)c(Cl)ccc3[nH]2)CC1 +CCCc1noc(COc2ccc(Cl)cc2)n1 +CCC(NC(=O)N1CCCC1CO)c1ccccc1Br +CC(Oc1cccc(Cl)c1)C(=O)NCc1nnc2ccccn12 +CC(C)(C)OC(=O)NCCNC(=O)C1CCOC1 +Cc1cc(NC(=O)c2ccc3c(c2)OCCO3)n(C(C)C)n1 +COc1ccccc1NC(=O)Nc1cccc(N2CCCCC2=O)c1 +CC(C)n1ncc2cc(CNc3cccnc3-n3cccn3)cnc21 +COC(=O)C(C)NC(=O)CC1CCC(C(F)(F)F)CC1 +Cc1ccc(-n2c(SC(C)C#N)nnc2N2CCOCC2)cc1 +Cc1cc(=O)n(CC(=O)NCCn2ncccc2=O)cn1 +FC(F)(Oc1cccnc1)C1=NC(Cc2ccccc2)CO1 +COc1ccc(C(=O)NC(C(=O)NC(C)C)C(C)C)cc1 +COc1ccc(Cc2nc3ccccc3[nH]2)cc1OC +CCC1CCCCC1NC(=O)N1CCN(S(C)(=O)=O)CC1 +COCC(=O)N1CCN(Cc2coc(-c3ccc(F)cc3)n2)CC1 +CCOC(=O)Nc1ccc(OC(=O)c2cc(C(N)=O)cs2)cc1 +C=CCOC(C)C(=O)NC(C)c1nc2ccccc2n1CC +Cc1noc(C)c1CN1C(=O)C2CCC1CN(c1ncccn1)C2 +CCOC1CCCN(S(=O)(=O)c2cccc(-n3cnnn3)c2)C1 +COc1ccc(NC(=O)OCC(F)(F)C(F)F)cc1 +N#CCCN(C(=O)c1csc(-c2ccoc2)n1)c1ccccc1 +COc1ccnc(-c2cccc(-c3ccn(Cc4cccnc4)n3)c2)n1 +COC(=O)CCNC(=O)c1ccc(-n2cnnn2)cc1 +O=C(CCCOc1ccc(Cl)cc1Cl)N1CCCCC1CO +Cn1cc(NC(=O)NCCN2CCN(c3ncccn3)CC2)cn1 +Cc1nc(C2CCCN(c3nnc(C(C)(C)C)o3)C2)no1 +N#CCCN1CCN(C(=O)c2sc3ccccc3c2Cl)CC1 +Cc1nc(C(C)(C)NC(=O)NCCNS(C)(=O)=O)sc1C +Cc1nnnn1-c1cccc(C(=O)NCc2ccc(Cl)cc2)c1 +CCOc1ccc(C(C)NC(=O)c2ccco2)cc1OCC +C#Cc1cccc(NC(=O)N2CCN(CC(=O)NC3CC3)CC2)c1 +COc1ccccc1-c1nn2c(=O)c(C)nnc2s1 +CC(Sc1ccc(N)cc1Cl)C(=O)N1CCCC1 +CCN1C(=O)C(Cc2cccs2)c2ccccc21 +CCCc1nc(C(=O)NC(C)(C)CO)nn1-c1ccccc1F +CCc1noc(CC)c1CNC(=O)c1ccc(CNC(N)=O)cc1 +O=C(Nc1ccc(Cn2cccn2)cc1)c1cn[nH]n1 +COCCn1cc(NC(=O)N2CCCC(C)C2CO)ccc1=O +O=C(Nc1nnc(C2CCCO2)s1)c1cc2ccccc2oc1=O +CCCNC(=O)CCNC(=O)c1ccc2[nH]cnc2c1 +Fc1cccc(Cl)c1CN1CC(c2nc(C3CC3)no2)C1 +NS(=O)(=O)c1ccc(N2CCN(Cc3n[nH]c(=O)[nH]3)CC2)cc1 +Cc1ccc(NC(=O)c2ccn(-c3ccc(F)cc3)n2)nc1 +COc1ccc(CNC(=O)Nc2nnc(-c3ccn(C)n3)o2)cc1 +Cc1csc(CNC(=O)N(Cc2ccc(C3CC3C)o2)C2CC2)n1 +COc1ccccc1C(C)NC(C)Cc1ccco1 +Cc1cccc(C(=O)Nc2ccnn2Cc2ccccc2)c1 +O=C(Nc1nnc(Cc2ccc(Cl)cc2)s1)c1cccnc1 +Cn1cc(-c2c(C#N)c(N)nc3c2COc2ccccc2-3)cn1 +CNC(=O)C1CN(C(=O)C(C)n2cccn2)c2ccccc2O1 +COc1ccccc1N1CCN(C(=O)c2c(C)nn(C)c2C)CC1 +CCOc1ccccc1NC1c2ncccc2C(=O)N1Cc1ccco1 +CNS(=O)(=O)c1cc(C(=O)Nc2ccc(F)cc2)cc(C)c1C +O=S(=O)(Nc1cccc(-n2cccc2)c1)c1ccc2c(c1)CCO2 +COCc1cccc(C(=O)N(Cc2ccc(Cl)cc2)C2CC2)c1 +CCOc1cccc(N2CCN(Cc3cc(C(N)=O)cs3)CC2)n1 +Cn1cc(CCNC(=O)CNC(=O)CC(C)(C)C)cn1 +Cc1cccc(NC(=O)COc2ncnc3sc4c(c23)CCC4)c1 +CC(C)n1c(C(F)(F)F)nc2cc(C(=O)N3CCOCC3)ccc21 +CCCCN(CC)C(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +O=C(CNC(=O)Nc1cccc(F)c1F)NC1CC1 +Nc1nccnc1C(=O)N1CCC(C(=O)N2CCCCCC2)CC1 +CCc1nc(C)cn1S(=O)(=O)c1ccc(F)c(Cl)c1 +COc1ccccc1-c1noc(-c2cccc(O)c2)n1 +CCOC(=O)C=C(Nc1ccc(O)cc1C)C(F)(F)F +Cc1ncsc1CNS(=O)(=O)CC(C)c1ccccc1 +NS(=O)(=O)c1cc(C(=O)Nc2cccc3cccnc23)cs1 +CN(C)C(=O)c1ccc2c(c1)N(C)C(CC(=O)NCC(C)(C)O)CO2 +CC(C)(C)c1ncc(NC(=O)c2ccc3ccccc3n2)cn1 +NC(=O)C1CCCN1C(=O)Nc1cccc(N2CCCC2)c1 +COc1ccc(OC)c(C2CC(=O)NC3=NC(C)=NC(=O)C32)c1 +CCCNC(=O)C(C)Sc1cccc(OC)c1 +CCCCn1c(N)c(N(CC)Cc2cc(C)no2)c(=O)[nH]c1=O +Cc1occc1C(=O)N1CCC2(CC1)NC(CC(C)C)=NC2=O +Cc1ccccc1N1CCCN(C(=O)C2CN(C)C(=O)N2)CC1 +CCS(=O)(=O)N1CCC(C(=O)Nc2cc(F)ccc2Cl)CC1 +CNC(=O)Nc1ccc(NC(=O)c2ccnc(OC3CCC3)c2)cc1 +CCN(CC)C(=O)Cc1nc2sc(C(=O)OC)c(C)c2c(=O)[nH]1 +COc1ccc(S(=O)(=O)N(CCC#N)C(C)C)c(C)c1 +COc1ccc(C(=O)OCC(=O)N(C)c2ccccc2)cc1OC +Cc1ccc(Cl)cc1-n1nnnc1-c1ccc(N)cc1 +O=C(NCCC(=O)N1CCCc2ccccc21)c1ccccc1O +CC(c1ccccc1)S(=O)(=O)c1ccc(Cl)cc1 +CN(CC1CC1)C(=O)CS(=O)(=O)c1ccc(C(F)(F)F)cn1 +Cc1ccc(C(=O)NCC(F)(F)F)cc1NC(=O)N(C)CC(C)C +OC(c1ccccc1)c1nc2ccc(F)cc2s1 +Cn1cc(S(=O)(=O)NCCc2ccccc2)c(=O)n(C)c1=O +CNc1nn2c(=O)c(-c3cccs3)nnc2s1 +O=C(c1ccco1)N1CCN(C(=O)c2cc3ccccc3o2)CC1 +Cc1cc(OC(C)C)ccc1NC(=O)NC(C)c1cn(C)nc1C +CC(c1ccc(F)cc1)N(C)C(=O)c1ccncc1 +COc1ccc(C(O)C(=O)N2CCNCC2)cc1Cl +CCc1c(C(=O)NCc2cccnc2)cnn1-c1ccc(F)cc1 +Cc1nc(C2CCCN(C(=O)CCc3cccnc3)C2)cc(=O)[nH]1 +CCn1c(SC(C)C(N)=O)nnc1-c1ccc(OC)cc1 +CCc1c(C)sc(NC(=O)CCC2CCCC2)c1C(N)=O +CC(Cc1ccsc1)Nc1nccc(C(F)(F)F)n1 +CCc1ccc(NC(=O)Cn2nnc(-c3ccccc3N)n2)cc1 +CC(NC(=O)c1cocn1)c1ccc(CNC(=O)c2cocn2)cc1 +COc1ccc(OC)c(-c2csc(NC(=O)C3CC3C)n2)c1 +Cc1cc(C)nc(N2CCC(NC(=O)C3CCCCC3)CC2)n1 +NC(=O)c1ccc(Cl)cc1NC(=O)c1ccnc(OC2CCC2)c1 +CCn1c(=O)c(SCC(=O)OC)nc2cccnc21 +CNC(=O)Cn1cc(NS(=O)(=O)c2c[nH]c3ncccc23)cn1 +CC(OCC(=O)Nc1ccc(F)c(N)c1)c1ccccc1 +O=C(OCc1nc(-c2ccsc2)no1)c1cnccn1 +CC(=O)c1ccc(-n2c(C)cn(CC(O)c3ccccc3)c2=O)cc1 +O=C(c1cccc(OC2CCCC2)c1)N1Cc2nn3nccnc3c2C1 +CCOC(=O)C1CCCN(c2ccn3nc(N)nc3c2)C1 +Cc1cc(C)cc(OCCN(C)S(N)(=O)=O)c1 +O=S(=O)(NCCc1ccccn1)c1ccc(Br)cc1 +CC(CCNC(=O)Cn1cnc2c(cnn2C)c1=O)c1ccccc1 +O=C(N1CCCCC1)N1CCN(c2nc3ccccc3o2)CC1 +CC(C)(C)OC(=O)N1CCC(CNc2cc(C#N)ccn2)CC1 +CCC(=O)Nc1sc(C(=O)OC)c(C)c1C(N)=O +COCCNC(=O)C1CCCN(S(=O)(=O)c2cccs2)C1 +Cc1ccccc1CNC(=O)Nc1ccnn1C(C)C +CCOc1ccc(-n2c(SCC#N)nnc2-c2cccnc2)cc1 +Nc1cccc(C(=O)Nc2cc(Cl)c(N)cc2Cl)c1 +CCCCn1nnnc1CN1CCCC1Cn1nc(C)cc1C +Cc1ccc(Cl)cc1NC(=O)CNC(=O)c1ccoc1 +O=C(Oc1cccc(N2CCCC2=O)c1)c1cc(-c2ccccc2)on1 +CCc1ccc(S(=O)(=O)N2CC(C(N)=O)CCC2C)cc1 +CS(=O)(=O)c1ccc(OCc2cc(-c3ccccc3)on2)cc1 +CCc1c(C)sc2nc(Cc3ccn(C(C)C)n3)[nH]c(=O)c12 +NC(=O)CCCNC(=O)COc1ccc(F)cc1 +CCOc1ccc(-c2ccc(CO)c(=O)n2C)cc1 +COc1cccc(-c2nnn(Cc3nnnn3C3CC3)n2)c1 +CCOC(=O)N1CCN(CCC(O)c2cccs2)CC1 +CCCCNC(=O)N1CCN(c2ccc(O)cc2)CC1 +CC(C)C1C(=O)NCCN1C(=O)Nc1nnc(-c2ccccn2)s1 +Cc1ccc(CCNC(=O)N2CCN(C(=O)N(C)C)CC2)c(C)c1 +CCCOc1ccc(-c2cc(CO)c(=O)[nH]n2)cc1 +Fc1cccc(N2CCN(c3cnccn3)CC2)n1 +CC(C)N(Cc1ccccc1)S(=O)(=O)c1cccc(C#N)c1 +CCC(C)NC(=O)c1ccc(NC(=O)c2cc(Cl)c[nH]2)cc1 +CCNS(=O)(=O)c1ccc(C)c(C(=O)OC2CCCC2)c1 +CC(=O)N1CCC(C(=O)NC2(c3noc(C)n3)CCCCCC2)CC1 +CCOc1cc(CNC(=O)N(CC)Cc2cccs2)ccn1 +CCOC(C)C(=O)NCc1c(C)cc(C)[nH]c1=O +CC(C)(O)C#Cc1ccc(C(=O)Nc2ccc3c(c2)OCO3)cc1 +CCN(C(=O)c1ccc(C)n1C)c1ccccc1C +CC(N(C)S(=O)(=O)c1cc(N)cc(F)c1)C(C)(C)C +C#CCNC(=O)CNC(=O)Nc1ccc2c(c1)Cc1ccccc1-2 +O=c1n(Cc2cccc(F)c2)nc(C2CC2)n1-c1ccccc1 +Cc1sc(=O)n(CC(=O)Oc2ccc(F)cc2)c1C +Cn1cc(C(=O)Nc2ccc(F)cc2Cl)ccc1=O +CNC(=O)NCC(=O)Nc1ncc(Cc2ccccc2F)s1 +NC(=O)C1CCCN1C(=O)CCc1ccc(-c2ccccc2F)o1 +COc1ccc(Cl)cc1-c1cc(C(C)(C)O)c(=O)n(C)n1 +C#CCN1CCN(S(=O)(=O)c2ccc(C)c(Cl)c2)CC1 +Cc1ccc(C)c(NC(=O)CCNC(=O)c2ccoc2)c1 +COc1ccc(C(=O)N2CCC(c3nc4ncccc4[nH]3)C2)cc1 +O=C(CCc1c[nH]c2ccccc12)NCCc1nc2ccccc2[nH]1 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1cc(F)ccc1F +O=C(CCc1ccccc1)N1CCN(Cc2cccc(F)c2)CC1 +Cc1ccc(C(=O)Oc2ccccc2Br)cn1 +COCCNC(=O)c1c(-c2ccccc2)nn2ccccc12 +Cc1cccc(NC(=O)N2CCN(Cc3cn(C)nc3C)CC2)c1 +Cc1ccc2ncc(C(=O)NC3(C)Cc4ccccc4C3)c(=O)n2c1 +CC1CCCCN1c1ncnc(Nc2ccccn2)c1N +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)N1CCc2ccccc21 +Cn1c(C(C)(C)C)nc2cc(NC(=O)c3ccco3)ccc21 +CCc1noc(CC)c1CNC(=O)Cc1cccc(F)c1 +COc1ccc(C(=O)NCC#CCOc2cccnc2)cc1 +CCCOc1ccccc1C1Nc2ccccc2C(=O)N1C +CC(=O)c1ccc(OCC(=O)NCCc2ccccc2F)cc1 +Cc1cc(C(O)CCNC(=O)c2cc(-c3ccccc3)on2)c(C)o1 +CC(O)CN1CCN(C(=O)Cc2cccc(Cl)c2)CC1 +Cc1cc(C)c(CNC(=O)OC(C)(C)C)c(=O)[nH]1 +CCOC(=O)Nc1ccc2c(COC)cc(=O)[nH]c2c1 +CCc1cnccc1C(=O)OCC(=O)Nc1ccc(F)cc1F +O=C(CCOc1ccc(F)cc1Cl)n1ccnc1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1cccc(-n2ccnc2)c1 +COc1cccc(NC(=O)CSc2nc(C)cc(=O)[nH]2)c1 +N#CC1(NC(=O)Cn2ncc(Cl)c(Cl)c2=O)CCCCC1 +CCOc1ccc(OCC(=O)NCc2ccsc2)cc1 +N#Cc1ccc(N2CCN(C(=O)C3CCC3)CC2=O)cc1 +CCC(=O)Nc1cccc(C(=O)Nc2ccc(C)cn2)c1 +COc1ccc(CNC(=O)NCCCO)cc1OC +COc1ccc(-n2cnnc2SCc2cc(C)on2)cn1 +COC(=O)C1(N(C)C(=O)c2ccccc2F)CCCCC1 +CNC(=O)c1ccc(Cl)c(NC(=O)Cc2c[nH]c3ccccc23)c1 +CCn1nnc2c(Nc3cccc(C)c3)ncnc21 +O=C(CC1CCCCC1)Nc1ccc(S(=O)(=O)NC2CC2)cc1 +c1ccc(-n2cnc(COCc3ncc[nH]3)n2)cc1 +COc1ccccc1-c1nnc(SC(C)c2nnc(C)o2)n1C +Cn1cnc(CNC(=O)NCCNC(=O)CC2CCCC2)n1 +CCc1nnc(NC(=O)CN(C)S(=O)(=O)c2ccccc2)s1 +CCc1ccc(C(NC(=O)NCC(C)(C)C(N)=O)C(C)(C)C)o1 +CC(=O)NCC(=O)N1CCN(CC(=O)N2CCCCC2C)CC1 +COc1ccc(Cl)cc1Nc1nc(N)nc(C2CCCC2=O)n1 +Nc1nc(-c2ccccc2)ncc1C(=O)N1CCCC1 +Cc1ccc2ncc(C(=O)NCc3cccc(F)c3)n2c1 +COC(=O)c1ccccc1OC(=O)C12CCC(C)(C(=O)O1)C2(C)C +COCC(C)NC(=O)NCC(c1ccc(F)cc1)N1CCOCC1 +CCOC(=O)c1ccc(CN2CCCC(c3nc(C)cs3)C2)o1 +CC(C)C(C)NC(=O)CN(C)c1ncnc2nc[nH]c12 +COC(=O)c1ccc(C(=O)NCC2CC2C)s1 +COc1cc(CNc2ncc(C)s2)ccc1O +O=c1n(Cc2cccc(Cl)c2)nc(C2CC2)n1-c1ccccc1 +CCCCNS(=O)(=O)c1cc(C(=O)C(C)C)ccc1F +CC1CN(C(=O)NCc2ccc(C#N)cc2)CCO1 +CCCOC(=O)CSc1nnc(C)c(=O)n1N +CC1(CNC(=O)CCNS(=O)(=O)c2ccc(F)cc2)CCCC1 +CCn1c(=O)oc2cc(NC(=O)Nc3ccccc3F)ccc21 +Nc1cnc(CS(=O)(=O)c2ccc(Cl)cc2)nc1 +CC(=O)Nc1ccccc1OCc1csc(C)n1 +CCc1cc(N2CCC3(CC2)CNC(=O)C3)nc(N2CCCC2)n1 +c1ccc(-c2csc(CN3CCOC(c4nccs4)C3)n2)cc1 +CC(C)CN1CCOC(CNC(=O)Cc2c[nH]c3ccccc23)C1 +CCSc1ncnc2cc(OC)c(OC)cc12 +Cc1cccc(C)c1NC(=O)CCC(C#N)c1ccccn1 +COc1ccc(CN2CCc3ncnc(OC)c3CC2)cc1 +CCCn1cnnc1C(C)Nc1ncnc2nc(C)cc(C)c12 +CCCOc1ccc(-c2ccc(CO)c(=O)n2C2CC2)cc1 +Nc1[nH]nc(-c2cccs2)c1-c1cccc(F)c1 +COc1ccc(C)cc1S(=O)(=O)N(CC(N)=O)Cc1ccco1 +NC(=O)N1CCCN(Cc2ncccc2C(F)(F)F)CC1 +O=C(COc1ccc(Cl)cc1)N1CCOCC1c1ncon1 +CC(C)Oc1nnc(SC(C)C(=O)NC2CC2)s1 +CN(C)c1ccc(C#CCNC(=O)Cc2cccs2)cc1 +CCOc1ccc2ncc(C#N)c(N3CCOCC3)c2c1 +CCOc1ccc(C(C)NC(C)C(=O)N2CCOCC2)cc1 +Cc1ccccc1C(=O)Nc1cc(N)ccc1Cl +O=C(c1cc(F)cc(F)c1)N1CCN(c2ccccc2O)CC1 +CCc1cccc(NC(=O)CN(C)C(=O)OC)c1 +CC(=O)c1cccc(NC(=O)c2cc(Cl)c3c(c2)OCCO3)c1 +CCOc1ccc(CNC(=O)NCC(C)(C)c2ccncc2)cc1F +Cc1cnc(-c2nnc(CNC(=O)CCc3ccccc3)o2)cn1 +CC(Oc1ccccc1)C(=O)Nc1ccccc1N1CCNC(=O)C1 +Cc1noc(C)c1CNC(=O)NCc1ccccc1Cl +CCCC(C)NC(=O)C(C)Sc1nnc(C)s1 +O=C(c1ccnc(-n2ccnc2)c1)N1CC=C(c2ccccc2)CC1 +COc1cccc(CC(=O)N2CCC(CN3CCOCC3)CC2)c1 +CC(C)N(C)c1ccc(NC(=O)NCCC(=O)N(C)C)cc1F +CC(C(=O)NCc1ccccc1)n1nnc(-c2ccccc2)n1 +O=C(NC1CC1)C(Sc1nc2ccccc2[nH]1)c1ccccc1 +CSc1nnc(CN2CCOC3CCCCC32)s1 +CC(C)CCC(=O)N1CCN(C(=O)c2cccc3ncccc23)CC1 +CC1CCC(C(N)=O)CN1C(=O)c1ccc2cc[nH]c2c1 +Cc1noc(CCCC(=O)N(C)CCC(F)(F)F)n1 +CCOc1ccccc1OCC(=O)N(C)c1cccc2ncccc12 +CCn1c(=O)c(C)nc2cc(C(=O)Nc3ccc4c(c3)CCC4)ccc21 +COc1cc(C)c(-c2csc3nc(N)nn23)cc1Cl +CNc1ccc(C(=O)NCc2ccc(Cl)cc2)nn1 +Cc1nc(C)c(C(=O)NCCNC(=O)c2ccc(F)cc2F)s1 +Cc1cc(OCCn2ccnc2)cc(C)c1Cl +Cc1cc2c(=O)n(CC(=O)Nc3ccccc3C#N)cnc2s1 +CC(NC(=O)c1cccc(-n2cc(Br)cn2)c1)C1CC1 +CN(Cc1ccco1)C(=O)c1cccc(S(C)(=O)=O)c1 +O=C(Nc1cccnc1)c1ccc(OC(=O)c2ccccn2)cc1 +COc1cc(CN2CC(C)OCC2C)cc2c1OCO2 +NC(=O)c1ccc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)cc1 +N#Cc1ccccc1NC(=O)c1cc2ccccc2c(=O)o1 +N#Cc1cnn(-c2nc(-c3ccc(Cl)c(Cl)c3)cs2)c1N +Cc1ccc2oc(C(=O)N3Cc4ccccc4CC3C(N)=O)cc2c1 +Cc1[nH]nc2c1NC(c1ccccc1OCc1ccccc1)NC2=O +CCn1c(C)cc(C(=O)Nc2ccccc2C(=O)NC(C)(C)C)c1C +COC(=O)C(CC(C)C)NC(=O)c1ccc(C)cc1 +CCCn1ccc2ccc(NC(=O)N3CCCC(C)C3CO)cc21 +CC1CC1C(=O)Nc1ccccc1NCC(F)(F)F +Cc1nnc(-c2c(C)[nH]c(C)c2S(=O)(=O)N2CCCCC2)o1 +CN(CCc1ccccn1)C(=O)CNC(=O)NCc1ccsc1 +CCS(=O)(=O)NCC(C)(C)c1cccc(Cl)c1 +Cc1cc(S(N)(=O)=O)sc1C(=O)NC(C)(C)C +Cc1ccccc1NC(=O)COC(=O)c1cccn1C +Cn1nnc2c(N3CCN(C(=O)CCC4CCCC4)CC3)ncnc21 +CCOc1nc(C)ccc1-c1noc(-c2ccccc2)n1 +COc1ccc(CCNc2nccn3cnnc23)cc1 +CN(C)C(=O)CN(Cc1cccc2c1OCO2)CC(F)(F)F +CCn1cc(C(=O)Nc2cccc(COC3CCCC(C)C3)c2)cn1 +CN1CCC=C(c2nc(CCNC(=O)c3cccs3)cs2)C1 +CCn1ncc(S(=O)(=O)NCc2ccco2)c1C +CCN(Cc1ccccc1)C(=O)CNc1cc(F)ccc1F +Cc1cnc(C(=O)NCc2sc(-c3ccccc3C)nc2C)cn1 +COc1ccccc1C(=O)OCc1nc(N)c2ccccc2n1 +CCc1nc(COc2ccc(Cl)cc2C(N)=O)cs1 +CCOC(=O)CN(C(=O)CC)c1ccc(F)cc1 +Cc1c(C(=O)Nc2cccnc2)nnn1-c1ccc(OC(C)C)cc1 +CCOc1ccccc1C(=O)NCc1ccc(S(N)(=O)=O)s1 +Cc1nc2n(n1)CCN(C(=O)c1cc(C3CC3)on1)C2 +CCOc1ncccc1CN(C)C(=O)NCc1ccccc1 +CC(C)Cc1nc(CNC(=O)C2CCCCC2)no1 +Nc1c(NC2CCCC2)ncnc1N1CCc2ccccc2C1 +CNC(=O)C1(NC(=O)COC(C)C)CCCCC1 +COc1ccc(Cl)cc1NCc1cccc(O)c1 +O=C(OCc1ncc(-c2ccc(Cl)cc2)o1)c1ccccn1 +Nc1nc(N2CCCC2)ncc1C(=O)N1CCc2ccccc21 +CSc1ccc(CN(C)S(=O)(=O)c2ccc(F)cc2)cc1 +COc1ccc(CC(=O)n2cnc3ccccc32)cc1 +Cc1ccsc1CNC(=O)C1COc2ccccc2C1 +CCOC(=O)CCC(=O)c1ccc(C)c(Cl)c1 +CN(C)C(c1ccc2c(c1)OCO2)c1ncnn1C1CCCCC1 +CCNC(=O)n1cc(-c2cnccn2)c(-c2ccncc2)n1 +CCC(NC(=O)Nc1c(F)cccc1F)c1ccc(OC)cc1 +CCNC(=O)c1ccc(NC(=O)c2cc(C)c(C)s2)c(C)c1 +O=C(c1ccc(C#CCO)cc1)N1CCCOCC1 +O=c1[nH]c2ccsc2c(=O)n1Cc1ccc(C(F)(F)F)cc1 +Cc1cc(C)n(-c2ccc(NC(=O)CCCCNC(N)=O)cc2F)n1 +O=C(Nc1cc(CO)ccn1)c1cccc(Cl)c1 +CC1C(=O)Nc2c(F)cc(C(O)C3CCCO3)cc21 +CCn1nc(C)cc1NC(=O)CCn1nc(C)c2ccccc21 +CCOc1cccc(NCC(=O)Nc2cccc(C(N)=O)c2)c1 +COC(=O)N1CCC(NC(=O)C2(c3cccc(F)c3)CCC2)CC1 +CCN(Cc1ccccc1F)C(=O)c1ccc(C#N)nc1 +CCc1noc(CC)c1CNC(=O)CCc1nc(C)no1 +Cc1csc(NC(=O)Nc2cnn(CCO)c2)n1 +CCCN(CCC)C(=O)c1csc(Nc2ncccn2)n1 +Nc1ncnc(Nc2cccc(C(F)(F)F)c2)c1N +COc1cc(CN2CCc3[nH]ncc3C2)cc2c1OCO2 +O=C(c1cncs1)N1CCOC(c2ccccn2)C1 +Cn1cc(S(=O)(=O)N2CCCC(O)C2)c2ccccc21 +CN(Cc1cnn(C)c1)C(=O)NC1CCOc2c(Cl)cccc21 +Cc1cc(C)n(-c2ccc(C(=O)NCCn3cnnc3C)cc2F)n1 +O=C(Nc1ccc(F)cc1OCC1CC1)c1ccsc1 +COC(=O)Cn1c(C(C)NC(C)=O)nc2ccccc21 +COc1ccc(Cn2cc(Br)cn2)cc1F +Cc1ccc(Nc2ncnc(N3CCCC(C)C3)c2N)nc1 +CC(=O)c1ccc(C(=O)N2CCC3(CC2)OCCCC3O)s1 +FC(F)(F)Cn1nnnc1SCc1cn2ccccc2n1 +Cc1ccc(Oc2ccc(S(C)(=O)=O)cc2)c(N)c1 +Cc1noc(C(C)OC(=O)CCc2nc(-c3cccs3)no2)n1 +COC(=O)CNC(=O)c1cc(=O)c2ccccc2o1 +Cn1ccc2c(NC(=O)c3[nH]nc4c3CCC4)cccc21 +O=C(Cc1ccc2c(c1)CCCC2)NCc1ccco1 +CCn1ccc(C(=O)NCC2CCN(c3cnn(C)c(=O)c3)C2)n1 +COc1ccc(NC(=O)N(C)C(C)CC#N)c(OC)c1 +CCCC(=O)OCC(=O)c1[nH]c(C)c(C(C)=O)c1C +CC(Oc1cccc(N)c1)C(=O)Nc1ccc(F)c(Cl)c1 +NC(C(=O)NCCCO)c1cc(F)c(F)c(F)c1 +CCn1nc(C(=O)Nc2cc(Cl)ccc2OC)ccc1=O +CC1CC(C)CN(C(=O)Nc2cccc(Cn3cccnc3=O)c2)C1 +Cc1ccc(C(O)(CCNC(=O)NCc2cc[nH]n2)C(F)(F)F)o1 +CCCC1CN(C(=O)C2CC2c2ccco2)CCO1 +CCOCC(=O)NC1CCc2c(ccc(=O)n2CCn2cccn2)C1 +CCCS(=O)(=O)NCc1ccc(NC(=O)c2ccco2)cc1 +Cc1nc(-c2ccncc2)cc(N2CCN(CCO)CC2)n1 +CNc1nc(-c2cc(-c3cccnc3)sc2C)cs1 +CN(CC(=O)NC1CCc2ccccc21)c1ncnc2[nH]cnc12 +Nc1nncc(-c2ccccn2)c1C(=O)NC1CC1 +NC(=O)c1cc2c([nH]c1=O)CCCC2NC(=O)C1CCCCC1 +O=C(OC1CCCCCC1)c1cnc2ccccn2c1=O +COC(=O)Nc1cc(NC(=O)c2ccc(OC(C)C)nc2)ccc1F +O=C(NCC1CCCO1)c1nnc(-c2cccnc2)o1 +CC(=O)N1CCOC2CCN(C(=O)c3cc[nH]n3)CCC21 +O=C(Nc1ccsc1C(=O)NCc1ccco1)c1cnccn1 +CN(C(=O)OC(C)(C)C)C1CCCN(C(=O)OCc2ccccc2)C1 +COc1cccc(-c2c(C#N)nnn2CCCO)c1 +COCCOc1ccccc1NC(=O)c1ccncc1 +CC(C)C(C)NC(=O)Nc1ccc(S(C)(=O)=O)cc1 +O=C(C1COc2ccccc2O1)N1CCN(Cc2cscn2)CC1 +O=C(Cc1cccc2ccccc12)N1CCOCC1CO +NS(=O)(=O)c1ccc(NCc2c(F)cccc2Cl)cc1 +COc1ccc(C(=O)CNc2cccc(C(C)=O)c2)cc1F +O=C(NCc1cscn1)c1cccc(COc2cccc(F)c2)c1 +Cc1cc(C)nc(C(C#N)C(=O)CCNC(=O)C(C)(C)C)n1 +CCCN(C)C(=O)c1cn2ccnc(-c3ccc(OC)cc3)c2n1 +O=C(CNCc1ccccc1Cl)c1ccccc1 +N#Cc1ccc(CNc2cc(Cl)ccc2C(N)=O)cc1 +Cc1cc(C)c(C(=O)NCc2nc3ccccc3s2)c(=O)[nH]1 +CCCCNC(=O)NCc1ccc(OC(C)C)nc1 +O=c1c2cnc3ncnn3c2ccn1Cc1cccnc1 +CC1=CC2(Nc3cc(-c4ccccc4)ccc3O2)C(C(N)=O)=C(N)O1 +CCn1cc(NC(=O)C2CCN(CC(=O)OC)CC2)cn1 +COc1ccc(-c2nc(C3CN(C)CCO3)no2)cc1 +CN(Cc1ccc(Cl)cc1)C(=O)COc1ccccc1C#N +O=C(Cn1nnc(-c2ccc(Cl)cc2)n1)NCc1ccccc1 +Cc1nnc2cc(N3CCN(Cc4cccn4C)CC3)cnn12 +CCc1ccc(CN(C)Cc2nc(-c3cccnc3)no2)o1 +N#Cc1c(F)cccc1NC(=O)c1ccccc1Cl +O=C(c1ccco1)N1CCOC(Cn2ccnc2)C1 +CN(CC(=O)NCCCN1CCCC1=O)c1ccc2ccccc2c1 +O=C(CCNC(=O)c1cc(Br)c[nH]1)NC1CCCC1 +COc1ccc(C=c2sc3ncnn3c2=O)cc1OC +CC(C)N(C)S(=O)(=O)NCCS(=O)(=O)c1ccccc1 +O=C(NCc1ccccc1)c1ccc(N2CCOCC2)nc1 +Cc1csc(=O)n1CC(=O)Oc1ccc(Br)cc1F +CC(C)(C)OC(=O)NCc1ccc(Cl)cc1CO +Cc1cc(NC(=O)CSc2nnc(C(C)C)n2C2CC2)n(C)n1 +Cc1nc2ncnn2c(C)c1CCC(=O)N1CCOC2CCCCC21 +O=C(NCCCN1CCCCCC1=O)c1ccc2c(c1)OCO2 +CCCCOc1cccc(-c2nc(N)nc(C)c2C(=O)NC)c1 +CNC(=O)CCc1cc(C)nc(C2CCN(c3ncccn3)CC2)c1 +Cc1ccccc1NC(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +O=C1OC(C(=O)NCc2ccco2)Cc2ccc(Cl)cc21 +O=C(NCc1nccs1)c1ccc(-c2ccccc2)[nH]c1=O +CC(=O)Nc1ccc(NS(=O)(=O)c2c(C)c(C)cc(C)c2C)cc1 +Cc1ccc(OC2CCN(C(=O)c3ccc[nH]3)CC2)nc1 +Cc1cc(C(=O)NCC(O)c2cc(Cl)cc(Cl)c2)c(C)o1 +CCOC(=O)CN(C(=O)c1cccc(C)c1)C(C)C +Cc1ccc(OCCNC(=O)c2cccc(N(C)C)c2)cc1 +Cc1ncc(Br)c(C2CCCCC2)n1 +COC(=O)C1C(=O)CCCN1C(=O)OC(C)(C)C +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1c[nH]nc1-c1cccnc1 +CC(C)(C)OC(=O)N1CCCC2(C1)NC(=O)c1ccccc1N2 +CC(=O)N1CCc2c(sc(NC(=O)C(C)(C)C)c2C(N)=O)C1 +Cc1n[nH]c(C)c1Cc1n[nH]c(=O)n1-c1ccc2c(c1)OCO2 +COc1ccc(C(=O)c2csc(C)n2)cc1OC +CC(C(=O)c1ccc(N)cc1)N1CCc2ccccc2C1 +CC(C)(C)OC(=O)N1CCC(NC(=O)N2CCOCC2)CC1 +C=C(C)CN(CC)C(=O)c1cc(-c2cccs2)nn1C +COc1ccc(SC(C)c2nc(C)no2)cc1 +C=C1C(OC(C)=O)CCC2(C)C=C3OC(=O)C(C)=C3CC12 +N#CCCN(Cc1ccc(Cl)cc1Cl)C1CC1 +Cc1c(C(=O)N2CCOC(C3CCCO3)C2)cnn1-c1ccncc1 +COC(=O)CCCC(=O)Oc1cccc(Br)c1 +Cc1nc2sc3c(c2c2nc(OCC(N)=O)nn12)CC(C)(C)OC3 +COc1cccc(CN(Cc2cncs2)CC2CCCO2)c1 +CC(C)(C)c1ccc(-n2nc(C#N)c3c2CCNC3)cc1 +CC(Sc1nnnn1C1CC1)C(=O)Nc1ccc(Cl)cn1 +N#Cc1ccc(CS(=O)(=O)c2ccc(O)cc2)cc1 +CCCc1nc(C)c(C(=O)N2CCNC(=O)C2)s1 +COc1ccccc1CNC(=O)C1Cc2cc(Cl)ccc2O1 +Fc1cncc(C2NCCc3cc(Cl)cc(F)c32)c1 +CC1(C)CN(C(=O)c2cc(Cl)c3c(c2)OCCO3)C1(C)C +O=C(CSc1ccncc1)OCC1CC(=O)N(C2CC2)C1 +CCCC(=O)NCc1nc2ccccc2n1CC(=O)N1CCOCC1 +CCn1cc(COc2ccc(F)cc2Br)cn1 +O=C(OCc1noc(-c2ccco2)n1)c1ccc(-n2cncn2)cc1 +Cc1nc2ccccc2nc1SC1CCOC1=O +Cc1cc(C)cc(C(=O)Nc2cccc(C#N)c2)c1 +Cc1cc(C)n2nc(CC(=O)OCc3ccccc3Cl)nc2n1 +O=C(NCCc1ccc(O)cc1)c1cc(C2CC2)[nH]n1 +CC(NC(=O)c1onc2ccccc12)c1cnn(C)c1 +CCOC(=O)CCCNC(=O)N1CCN(c2ccccc2)CC1 +CC(C)CNC(=O)c1cccc(Br)c1 +CCNC(=O)CN1CCc2nc(NC(=O)c3ccco3)sc2C1 +COc1cccc(CN(Cc2cccs2)CC2CCCO2)c1 +CCC(=O)N1CCc2c(C(=O)NCCCOC)cccc21 +CNC(=O)C1CCN(C(=O)c2ccc(OC(F)F)cc2)CC1 +Cc1ccc(-c2csc3ncn(CC(=O)N(C)C)c(=O)c23)cc1 +Cc1ccc(C(=O)OC(C)c2c(F)cccc2-n2cncn2)c(=O)[nH]1 +C#CCNC(=O)N(C)C(C)c1ccc(Cl)cc1 +CN(Cc1ccccc1N1CCCC1)CC(C#N)CCC#N +O=C(CCCc1nc2ccccc2o1)N1CCOC2CCCC21 +O=C(Nc1ccc2c(c1)-c1ccccc1C2)c1cnccn1 +CCOc1ccc(NC(=O)c2cn(C)c3ccccc3c2=O)cc1 +CN(C)c1ccc(C(=O)NCC2CCCO2)cc1F +Cc1ccccc1NC(=O)c1ccc(NC(N)=O)cc1 +Cc1cnc(CS(=O)c2nnc(C)n2CCc2cccs2)o1 +CC(C)c1nc(CN2CCc3cc(Br)ccc32)no1 +CN(C(=O)Cc1cccnc1)C1CCN(CC(F)(F)F)C1=O +Cc1nn(C2CCCC2)c2[nH]c(-c3ccoc3)nc12 +COc1ccc2c(c1)CN(C(=O)NCCCc1c(C)noc1C)CC2 +CCc1n[nH]c(Sc2ccc(N)cc2C(=O)OC(C)C)n1 +CC(C)c1cc(C(=O)Nc2ccc(C#N)cc2)nc(N(C)C)n1 +Cc1nc(C)n(C2CCCN(C(=O)c3cc(C4CC4)on3)C2)n1 +Cc1ccc(CN(C)C(=O)Cn2c(-c3cccnc3)noc2=O)o1 +CCCOCC1CCN(C(=O)c2cc(CCC)n[nH]2)C1 +CN(Cc1ccc(F)cc1Cl)c1nccnc1C#N +Cc1nc(COc2cccc(Cl)c2Cl)nc(C)c1N +Cc1ccc2ncc(C(=O)NCCOc3cccnc3)n2c1 +CC(=O)c1cc(Cl)ccc1OCC(=O)Nc1sccc1C#N +COc1ccccc1NC(=O)Cc1noc(C(=O)NCC2CC2)n1 +C=CCn1c(=O)c(C(=O)Nc2cccc(F)c2)c(O)c2ccccc21 +Cc1cc(C)cc(C(=O)NCC(O)c2cn(C)c3ccccc23)c1 +COCC(C)C(=O)N1CCOC(c2ccccc2C(F)(F)F)C1 +C=CCn1nc2ccc(S(=O)(=O)N3CCOCC3)cn2c1=O +O=C(c1ccc(O)c(Cl)c1)N1CCC(C(=O)N2CCCC2)CC1 +Cc1cc(CNC(=O)Nc2ccc3c(c2)OC2(CCCC2)O3)no1 +COc1ccc(S(=O)(=O)c2c(C)cc(C)[nH]c2=O)cc1OC +COc1ccc(OCC(=O)N(C)Cc2ccc(C)cc2)cc1 +O=S(=O)(Nc1cccc(Cl)c1)c1ccc2c(c1)CCN2 +CCc1ccccc1NC(=O)CN(C)C(=O)Nc1cnn(C)c1 +O=C(NC1CCCN(c2ncccn2)C1)c1ccccn1 +COc1ccc(NC(=O)CSc2nc3ncccc3o2)cc1 +COc1ccc(CC(=O)Nc2nnc(-c3ccc(F)cc3F)o2)cc1 +COCCN1CCN(C(=O)c2cc3occc3[nH]2)CC1=O +CCCCn1c(-c2cccc(OC)c2)ccc(CO)c1=O +CCCCCCn1cc(C(=O)NC2CC2)c(=O)c2c(N)cccc21 +O=C(NCc1cn(-c2ccccc2)nn1)NC1C=CCCC1 +NC(=O)c1ccc(NC(=O)OCC(F)(F)F)cc1 +CCOc1cc(C)c(C(=O)NCCCO)cc1C +CNC(=O)c1ccc(Cl)c(NC(=O)CCc2c(C)nn(C)c2C)c1 +Cn1cnnc1C1CCN(c2cc(Cl)c3cc[nH]c3n2)CC1 +COC(=O)Nc1nc(CC(=O)NCc2ccccc2Cl)cs1 +Cc1nnsc1C(=O)NC1(c2ccc(F)cc2)CCCC1 +COCCCCNS(=O)(=O)c1ccc(N)nc1 +CCC(=O)Nc1ccc(NC(=O)NCc2ccccc2CO)cc1 +COc1ccc(S(=O)(=O)C2CN(C(=O)c3cnccn3)C2)cc1 +O=C(c1ccccn1)N1CCCCC1c1nncn1Cc1ccccc1 +COc1cc(S(=O)(=O)NCc2ccccc2)ccc1NC(C)=O +CCCCc1cc(NC(=O)Cc2c(C)noc2C)[nH]n1 +COc1cc(-c2cc(OC)c3c(C)oc(C)c3c(=O)c2)ccc1O +CC(=O)c1ccc(NC(=O)c2cc(C(C)C)n(C)n2)cc1C +CC(=O)N1CCN(c2ccc(O)cc2Cl)CC1 +CC1COCCN1C(=O)C1CCCN(c2cnccn2)C1 +CC1CN(Cc2cccc(NC(=O)c3ccccc3)c2)CC(C)O1 +CCC(=O)N1CCCCC1C(=O)Oc1ccc(Cl)c(C)c1 +Cn1c(CCNC(=O)COC2CCCCC2)nc2ccccc21 +O=C(c1ccc(F)cc1)N1CCC(c2nc(-c3ccccn3)no2)C1 +Cc1cc(=O)[nH]c2nnc(SCC(=O)N(C)c3ccccc3)n12 +CC(C)Cn1nnnc1SCc1noc(C2CC2)n1 +C#CCN1CCC(C(=O)Nc2cc(C)ccn2)CC1 +CN(CC(=O)OCC1CCCCC1)S(C)(=O)=O +Cc1noc(COC(=O)C2CC(=O)Nc3ccccc32)n1 +Cc1ccc(CC(=O)N2CCn3cccc3C2C)s1 +CCCCNC(=O)c1ccccc1NC(=O)C(C)CC +COc1cccc(C(=O)NCCCOc2ccccc2)c1F +Cc1noc(C)c1CC(C)NCc1cc(F)ccc1Br +Cc1cc(CNC(=O)Cn2nc(-c3ccccc3)ccc2=O)c(C)o1 +COc1ccc(-n2nc3ccc(N)cc3n2)cc1Cl +CCOc1cccc(CNC(=O)c2cc(F)cc3[nH]cnc23)c1 +COCc1nc(OC)c2c(C)c(C(=O)Nc3cc(C)on3)sc2n1 +N#Cc1cc(F)ccc1Cn1cnc2ccccc2c1=O +CC(C)CN1CC23CN(C(=O)NC(C)C)CC(CC2S1(=O)=O)O3 +CC(C)(NC(=O)c1ccn(-c2ccccc2)n1)C(=O)Nc1ccccc1 +C=CCNC(=O)CSc1cc(N2CCCCC2)ncn1 +CCCN(CC)C(=O)c1cc(OC)ccc1Br +O=c1[nH]nc(-c2ccc(F)cc2)cc1Cc1cccnc1 +CC(Oc1ccc(C#N)cc1)C(=O)NCC#Cc1ccccc1 +CC(C(=O)N(C)C)N1CCN(C(=O)CCC2CCCC2)CC1 +Cc1cc(CNC(=O)Nc2cnn(CC3CCCO3)c2)ccc1F +Cc1noc(C)c1S(=O)(=O)N(C)C(=O)c1cccc2c1ccn2C +CS(=O)(=O)N1CCn2c(Cn3cncn3)cnc2C1 +Cc1nc2ccc(O)cc2c(=O)n1CC(=O)NCCC(C)C +CC(Oc1cccc(Cl)c1Cl)C(=O)C(C#N)c1ccccn1 +CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2nccs2)C1 +Cc1[nH]nc(C(N)=O)c1NC(=O)c1cc(-c2cccs2)n[nH]1 +Cc1cc2nc(C(=O)Nc3ccc4c(c3)OCCO4)cc(C)n2n1 +CN(CC(=O)NCc1ccc2c(c1)OCO2)c1ccc(F)c(F)c1 +Cc1noc(C)c1CCC(=O)NC1CCCN(c2ncccn2)C1 +O=C(C1CCC1)N1CCC(c2cc3nccnc3[nH]2)CC1 +Cc1ccc(Cl)c2sc(N3CCOCC3)nc12 +CCCc1nccn1-c1ccc(C(F)(F)F)nc1 +COc1ccc(Cl)cc1NC(=O)c1ccc(CNC(C)=O)cc1 +CC(=O)Nc1cccc(NC(=O)c2ccccc2OC(F)F)c1 +Nc1nccnc1-c1nc(-c2ccccc2F)no1 +COc1ccccc1NC(C)C(=O)Nc1ccc2c(c1)OCCO2 +O=C(Cc1ccc(F)cc1)N1C2CCC1CC(O)(c1ccco1)C2 +COc1c(Cl)ccc2c1C(c1cnn(C)c1)NCC2 +Cn1cccc1C(=O)Nc1nc(-c2ccc(F)cc2)ns1 +Cc1nc(CNc2cc(F)ccc2Br)oc1C +Cc1ccc(C)c(N(C(=O)CCOCC(F)(F)F)C(C)C)c1 +CNC(=O)c1ccccc1C#CCNC(=O)c1ccc2ncsc2c1 +COC(=O)N(C)CC(=O)NC(C)Cn1cccn1 +O=C(NCC1Cn2ccnc2CO1)c1ccc(Cl)cc1 +CC(=O)c1ccc(NC(=O)c2cnn(Cc3ccccc3)c2)cc1C +Cn1nc(-c2ccccc2)cc1C(=O)Oc1ccc2c(c1)ncn2C +CCN(CC(=O)NC(C)C)c1ccccc1CO +COC(=O)CCSc1nnc(-c2ccoc2C)n1C +Cc1nn(-c2ccccc2)nc1C(=O)NCC(=O)N(C)C +CCOC(=O)CCC(C)NC(=O)c1cccc(Cl)c1 +COc1ccc(-c2nnc(SCc3cccnc3)n2N)c(OC)c1 +O=C1CCN(C(=O)Nc2ccc(C(F)(F)F)cc2)CCN1 +CCCCn1nc(NCc2cccc(O)c2)cc1C +COc1ccc(C(=O)c2c(N)oc3ccc(F)cc23)cc1 +Cc1nnsc1C(=O)NCCNC(=O)c1snnc1C +CC(=O)c1cccc(NCc2cccc(C#N)c2)c1 +O=c1c(Cl)c(Cl)cnn1Cc1ncc(-c2cccs2)o1 +COC(=O)N1CCC(CNC(=O)Nc2ccccc2Cl)CC1 +O=C(Cn1nc(-c2cccs2)oc1=O)Nc1ccccc1 +COc1ccc(C(=O)NCc2ccco2)cc1Cl +CC(=O)c1ccc(NC(=O)N2CCC3(CCOCC3)CC2)cc1 +COc1cccc(CN2CCNC(=O)C2CC(=O)NC(C)(C)C)c1 +O=C(NC1CCOc2ccccc21)N1CCN(c2cnccn2)CC1 +O=C(Cc1cccs1)N(Cc1ccsc1)C1CC1 +CCN(C)C(=O)c1cccc(C(=O)N2CCOc3ccc(F)cc32)c1 +Cc1n[nH]cc1CNc1ccc(F)cc1OC1CCCC1 +CCCNc1cc(C(=O)Nc2cnn(C)c2)ccn1 +COC(=O)Nc1cccc(C(=O)NC2(C)Cc3ccccc3C2)c1 +COc1cccc(-c2nnc(NC(=O)c3ccccc3F)o2)c1 +COC(=O)c1ccc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)o1 +CC(C)c1nnc(SCC(O)C(F)(F)F)n1C1CC1 +CN(C)C(=O)c1cc(NC(=O)NCc2ccc3ccccc3c2)ccn1 +Cn1cc(C(=O)N2CCN(c3ccc(F)cc3)CC2)cn1 +Cc1nn(C(C)C)c(C)c1S(=O)(=O)NC(C)C(=O)N(C)C +Cc1ncc(Cn2c(=O)oc3cc(Br)ccc32)s1 +Cc1nnc(SC(C)C(=O)Nc2cc(Cl)ccc2C)s1 +Cc1noc(C)c1CC(=O)NC(C)c1cccc(S(N)(=O)=O)c1 +CN(C)C(=O)Cn1cc(C(=O)NCC2(c3ccc(F)cc3)CC2)nn1 +CC(=O)Nc1ccc(NC(=O)C2CC(=O)N(C3CCCC3)C2)cc1 +Cc1ncc(C(N)=O)c(CCNS(=O)(=O)c2ccccc2)n1 +Cc1ccnn1CCCNC(=O)c1ccc(F)cc1 +Cc1ccc(SCCNC(=O)NCC(=O)Nc2cccnc2)cc1 +Cc1ccc(C(=O)N(Cc2ccccc2)c2ccccn2)cn1 +c1coc(-c2nc(NCC3CCCO3)ncc2-c2ccncc2)c1 +Cc1ccc(S(=O)(=O)Nc2cc(N)ccc2F)cc1 +CC(OCC1CC1)C(=O)Nc1cc(C(F)(F)F)ccc1F +CN(CCOc1ccccc1)C(=O)c1ccnc(OC2CCC2)c1 +CCC(C)NC(=O)c1ccc(-c2ccc(OC)cc2)nc1N +O=C(Cc1noc2ccccc12)NCc1ccncc1 +Cc1cc(C(F)(F)F)nn1CC(=O)NCc1ccccc1Cl +CC(C)(CCC#N)CNc1cnn(-c2ccc(C(F)(F)F)cc2)c1 +CCNC(=O)CNC(=O)c1csc(-c2ccsc2)n1 +CC(C)n1nnc2cc(C(=O)Nc3cccc(F)c3)ccc21 +Cc1cccc(S(=O)(=O)CCCn2nc(C)nc2C)c1 +CC1=CCN(C(=O)NCc2ccc3c(c2)OCO3)CC1 +CCOC(=O)N1CCC(NC(=O)c2cnn(C)c2N)CC1 +Cc1nc2cc(Br)cc(Br)c(=O)c2o1 +CC(=O)Nc1ccc(O)c(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)c1 +COc1cc(C(=O)N2CCC(C(C)C)C2)cc2c1OCCO2 +CC1CCN(C(=O)c2cccc3[nH]ccc23)C(C)C1 +COC(=O)CCS(=O)(=O)c1c(Cl)cccc1Cl +CCSc1nc2n(n1)C(c1ccc(F)cc1)C1C(=O)CCCC1=N2 +CCn1nc(NC(C)=O)c2cc3ccccc3nc21 +Cc1cc(N)nc(SCC(=O)Nc2ccc3c(c2)OCCO3)n1 +CCn1cnnc1-c1cccc(NC(=O)c2ccc(C)c(F)c2)c1 +COc1cccc(C2=Nc3ncnn3C(c3cccc(OC)c3)C2)c1 +CCOCc1ncn2c1CN(C(=O)c1sccc1C)CC2 +COCCN(Cc1ccco1)C(=O)Cn1cnc2c(cnn2C)c1=O +CCCc1noc(C(C)Sc2ccc(C(=O)N3CCCC3)cn2)n1 +Cn1cnc(CNC(=O)NCCOc2ncccc2Cl)n1 +CCOC(=O)c1nnn(Cc2cccc(C#N)c2)c1N +CCC(C)NC(=O)NCCN(CC)c1ccccc1C +CC(C)(C)OC(=O)N1CCCC1CNc1cnc2ccccc2n1 +COC(=O)c1ccc(CNC(=O)CCc2c(C)nc(C)[nH]c2=O)cc1 +O=C(NCCCNc1ccccc1)Nc1cccnc1-n1cncn1 +CCCC1CN(C(=O)CCCNC(=O)NC2CCCCC2)CCO1 +Cc1cccc(CN2CCN(C(=O)Cc3cccnc3)C(C)C2=O)c1 +COC(=O)NCC(=O)NCCCc1ccc(Cl)c(Cl)c1 +Cc1cc(C(C)NC(=O)c2c[nH]c3ccccc3c2=O)c(C)s1 +N#Cc1ccc(C(=O)Nc2ccc(F)c(C#N)c2)nc1 +COc1ccc(N)cc1N(C)S(=O)(=O)N(C)C +Nc1cccc(C(=O)NCc2ccc3c(c2)OCO3)c1 +CC1CN(C(=O)C2CC(=O)N(Cc3ccco3)C2)CC(C)O1 +CN1CC(C(=O)Nc2cccn(Cc3ccc(F)cc3)c2=O)CC1=O +COc1ccc(C(C)NC(=O)c2cccc(F)c2N)cc1 +O=C(Nc1cccc2cccnc12)c1cc(F)cc(F)c1 +Nc1cccc(NC(=O)CSc2nncs2)c1 +Cc1nnc(NC(=O)NCc2cnn(C)c2)s1 +CCCOc1ccc(C(=O)CN2CCc3ccccc3C2)cc1N +O=C(NCc1ccccc1)c1cn[nH]c1C(F)(F)F +Cc1cc(S(C)(=O)=O)ccc1NC(=O)c1sccc1C(C)C +NC(=O)CNC(=O)c1cccc(OC(=O)C2CC=CC2)c1 +Cc1nc2ccc(NC(=O)COc3cccc4cccnc34)cc2s1 +CCNC(=O)C1CCCN(c2c(F)cc(C#N)cc2F)C1 +C=CCn1nnnc1SCC(=O)Nc1ccc(OC)c(Cl)c1 +CCCCN1C(=O)CCC2CN(C(=O)Cc3cc(C)no3)CCC21 +O=C(NC1CC(=O)N(C2CC2)C1)c1c(F)cccc1Cl +O=S(=O)(NCC#Cc1ccccc1F)c1c(F)cccc1F +COC(=O)C(NS(=O)(=O)c1cccnc1)c1ccccc1 +CC(=O)Nc1nc(C2CCN(C(=O)c3ccn(C)n3)CC2)cs1 +CCCCn1nccc1NS(=O)(=O)c1cccc(Cl)c1C#N +Cn1cnc(CNC(=O)NC(Cc2ccccc2)c2ccccc2)n1 +COc1ccccc1NC(=O)CNc1cccc(NC(C)=O)c1C +Nc1ccc2nc(NC(=O)CN3CCOCC3)sc2c1 +Cc1nn(CCS(=O)(=O)c2ccccc2)c(=O)c(C#N)c1C +COc1cc(-c2noc(-c3cn(CC(=O)N(C)C)nn3)n2)ccn1 +CC1Oc2ccccc2OC1C(=O)Nc1cc(-n2cncn2)ncn1 +CCn1nccc1CNC(=O)Nc1cc(OC)ccc1OC +CS(=O)(=O)c1ccc(CN2CCCC(c3cnccn3)C2)cc1 +O=S(=O)(Cc1cccc2ccccc12)c1ncn(-c2ccccc2)n1 +COc1cc(Cl)ccc1C(=O)NCCc1n[nH]c(-c2ccco2)n1 +COc1ccc(S(=O)(=O)Nc2cccn(C)c2=O)cc1Cl +Cc1nn(C)c(C)c1OCC(=O)Nc1ccc(Cl)cc1O +CNC(=O)CSc1nnc(-c2ccc(F)cc2)n1-c1ccccc1 +Cc1ccc(C=Cc2onc3c(=O)n(C)nc(C)c23)cc1 +C=CCNC(=O)Nc1cccc(-c2ccc(=O)[nH]n2)c1 +Cn1ncc2c(=O)[nH]c(CN3CCCC(N4CCNC4=O)C3)nc21 +O=C(NCc1nc(-c2ccncc2)no1)c1cc2c([nH]c1=O)CCC2 +CCCNC(=O)C1CN(C(C)=O)c2ccccc2O1 +COc1ccc(NC(=O)COc2ccc(C)cn2)cc1Cl +Cc1nc(SCc2ccccc2F)[nH]c(=O)c1CC(=O)NC1CC1 +CCN(CCNc1nccc(-c2cnn(C)c2)n1)c1cccc(C)c1 +COc1ccc(OC)c(C(O)CN(C)Cc2cc(C)on2)c1 +COc1ccnc(NC(=O)Cc2ccc(OCC#N)cc2)c1 +Cc1nn(C)c(NC(=O)CCCn2ccc3cc(Cl)ccc32)c1C +O=S(=O)(C1CC1)N1CCOC2C(Oc3cccnc3)CCC21 +O=C1CCN(C(=O)NCC2CC23CCCc2ccccc23)CCN1 +CCCc1nc(CS(=O)(=O)c2ccc(C(F)(F)F)cn2)no1 +Cc1cccc(NC(=O)CSc2ccc(N)nc2)c1 +CC(C)NC(=O)NCc1ccc(C(=O)NCc2cccnc2)cc1 +CCc1cc(=O)[nH]c2cc(NC(=O)c3ccc4ccccc4n3)ccc12 +O=C(NCCN1CCOCC1)C1(c2cc(-c3ccccc3)on2)CC1 +COc1ccccc1C1(CNC(=O)Cc2ccc[nH]2)CCCC1 +COc1cccc(OCC(=O)N2Cc3cncnc3C2)c1 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccc(OCC2CC2)nc1 +CC(C)N(CC(F)F)C(=O)C1CN(Cc2ccccc2)CCO1 +COc1ccc(F)cc1NC(=O)C(C)NS(C)(=O)=O +CC1(C)OCC2(CO1)CN(S(=O)(=O)c1ccccc1)C2 +N#Cc1cccc(OCCSc2nncn2C2CC2)c1 +CCc1c(C(=O)NCCO)cnn1-c1ccccn1 +CC(=O)c1ccc(NC(=O)c2cnc(-c3ccccc3)nc2C)cc1 +CCCCNC(=O)CC1CSc2nc3c(c(=O)n21)CCCC3 +CC(NC(=O)Nc1cccc(C(=O)N(C)C)c1)c1cccc(Cl)c1 +O=C1CN(C(=O)CCCc2cccs2)CCN1 +COc1ccccc1C(C)NC(=O)C(C)n1c(=O)oc2ccccc21 +O=c1cc(CSc2ncccn2)[nH]c2nc(-c3cccnc3)nn12 +Cc1nc(CC(=O)NCc2ccccc2Cn2ccnc2)cs1 +C=CCNC(=O)Nc1ccc(NCc2ccc(S(C)=O)cc2)cc1 +CCc1n[nH]c(C2CCN(C(=O)c3cc(Cl)ccc3F)CC2)n1 +COc1ccc(C(=O)Nc2ccc(Cc3nnc(C)o3)cc2)cc1 +CCn1cc(CN(C)C(=O)c2c(Cl)c(C)nn2C)cn1 +O=C(Cc1c(F)ccc(F)c1F)NCc1cccc(-n2cccn2)c1 +COc1ccc(C(=O)C2CCN(C(=O)NC3CC3)CC2)cc1 +CCSc1ccccc1C(=O)N1CCCCC1CC +CCOc1ccc(NC(=O)N2CCN(C(=O)N(C)C)CC2)cc1C +COc1cccc(CNC(=O)NCC2Cc3ccccc3O2)c1 +CC(C1CC1)N(C(=O)CSc1nnc(-c2ccco2)n1N)C1CC1 +CN1CC(C(=O)NCCCn2cccn2)CC1=O +Cc1nc(CC(=O)Nc2cccc(C(N)=O)c2)cs1 +Cc1cccc(S(=O)(=O)N(C)C(C#N)c2ccccc2C)c1 +COCCN(Cc1ccco1)C(=O)c1ccc(-n2ccnc2)cc1 +O=C(NCCOc1ccccc1)Nc1cc(N2CCCC2)ncn1 +CNC(=O)c1ccc(OC)c(NS(=O)(=O)c2ccc(C)c(C)c2)c1 +CCCS(=O)(=O)NCC(C)(C)NS(C)(=O)=O +COC(=O)c1cc(CNC(=O)Cc2csc(C)n2)ccc1OC +CC(C)c1nc2cc(C(=O)Cn3cccn3)ccc2[nH]1 +Cc1cccc(NC(=O)c2sc3ncn(C)c(=O)c3c2C)c1 +O=C(Nc1ccc(F)cc1F)c1ccc(N2CCOC2=O)cc1 +COc1ccc(F)c(-c2nc(OC)cc(OC)n2)c1 +COC(=O)c1ccc(COc2ccc(-n3cncn3)cc2)cc1F +CC(=O)Nc1ccc(C)c(NC(=O)N(C)Cc2ccc(F)c(F)c2)c1 +CC(Cc1cccs1)NC(=O)NCCCN1CCCCCC1=O +CCOCCC(=O)NCc1ccc(F)cc1C(F)(F)F +COCCCN1C(=O)c2ccccc2NC12CCCc1ccccc12 +CCN1CC2(CCC1=O)CCN(C(=O)c1ccc(F)cc1C)CC2 +COc1ccc(CNS(=O)(=O)Cc2ccon2)cn1 +c1cc(CN2CCOC(c3nccs3)C2)c2[nH]ncc2c1 +CC(NC(=O)Nc1ccc(Oc2cccnc2)nc1)C1CCCO1 +Cc1noc(C)c1C(=O)Nc1cnn(Cc2cn3ccccc3n2)c1 +CCS(=O)(=O)c1noc(C(=O)Nc2ccccc2C)c1N +COc1cccc(OCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1 +O=C(c1ccc(Cl)cc1-n1cnnn1)N1CCOCC1 +CCc1ccc(Cn2nc(C)c(C(C)O)c2C)cc1 +Cc1ccc2c(c1)CCCN2C(=O)Cn1ccc(=O)[nH]c1=O +NC(=O)C1CN(C(=O)CCc2ccc(F)c(F)c2)CCO1 +Cc1cccc(C(O)c2cc3[nH]c(=O)[nH]c3cc2C)c1 +COCC(C)N(C)S(=O)(=O)c1ccccc1Br +N#Cc1ccc(CN2C(=O)C(=O)c3c(Br)cccc32)cc1 +COc1cccc2c(=O)n(Cc3cccnc3)cnc12 +CC(C)C(=O)Nc1cccnc1-c1ccc(-c2ccn[nH]2)cc1 +Cc1ccc(-c2noc(C(=O)N3CCOCC3)n2)cc1 +CCCCOC(=O)c1ccc(NC(=O)c2cn(C)nc2C)cc1 +O=C(Nc1cccc(Cl)c1)c1cc2cc(F)ccc2[nH]1 +Cc1nnc(C(=O)Nc2cccc(C(F)(F)F)c2)n1C +CCCC(=O)Nc1cccc(NC(=O)NCc2cccnc2)c1C +CCCCC(=O)N1CCN(CC(O)c2cccs2)CC1 +CCOC(=O)c1cc(-c2ccc(OC)cc2C)[nH]c(=O)n1 +CCN(CC1CCOC1)C(=O)c1csc(-c2ccccc2OC)n1 +O=S(=O)(Cc1ccccc1Br)c1ccccc1 +COc1cccc(C(=O)NCCOc2cccc(C)c2)c1 +CC(C(=O)Nc1ccccc1C(N)=O)c1ccsc1 +O=c1[nH]c2sc3c(c2c(=O)n1CCc1ccccc1)CCCC3 +CCN(CC)c1ncc(CNC2CCc3ncnn3C2)s1 +CC(O)(CNC(=O)c1cnccn1)c1cccs1 +CCc1nc(CSc2nnnn2-c2ccccc2OC)cs1 +CC(CNC(=O)c1cccc(NC(=O)C2CC2)c1)Oc1ccccc1 +O=C1CN(C(=O)c2cncc(Br)c2)c2ccccc2N1 +O=C(NCC1CCN(c2ccc(F)cc2)C1)c1cc(Cl)ccn1 +N#Cc1ccc(-c2noc(CCSc3ccccc3)n2)nc1 +Cc1csc(NC(=O)N(C)Cc2ccoc2C)n1 +CNC(=O)C1Cc2ccccc2CN1C(=O)Cn1cc(C)cn1 +COc1ccc2c(c1)[nH]c(=O)n2Cc1cccc(N)c1 +Nc1cc(S(=O)(=O)N2CCOCC2)ccc1N1CCCCCC1 +O=C(CCCNC(=O)c1ccco1)Nc1nc2c(s1)CCCC2 +CS(=O)(=O)N(Cc1ccccc1F)c1ccc(C#N)cc1 +O=C(c1cccn1CCc1ccccc1)N1CCCC1Cn1cccn1 +COC(=O)C1C2C=CC3(CN(CCc4ccccc4)C(=O)C13)O2 +Cc1cc(C(=O)OCC(=O)N2CC(=O)Nc3ccccc32)no1 +Cc1cnn(C2CCCN(C(=O)CCc3ccco3)C2)c1 +CC(NC(=O)c1cccs1)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +CCn1cc(-c2ccc(C)cc2)cc1C(=O)NCCN1CCOCC1 +Cc1ccncc1NC(=O)N(C)Cc1cccc(F)c1 +CCc1nsc(SC(C)C(=O)NC2(C#N)CCCCC2)n1 +CCOc1c(Cl)cccc1NC(=O)c1ccccn1 +CC(=O)Nc1ccc(C(=O)OCC(=O)Nc2cc(F)cc(F)c2)cc1 +Cc1cc(-c2c(C#N)c(N)nc3c2C2CCC(C3)N2)oc1C +CNc1ccc(S(=O)(=O)NCc2cc(C)on2)cn1 +COCc1cc(Br)c(COC)cc1Br +Nc1ncc(-c2nnnn2-c2ccc(Cl)cc2)c(C(F)(F)F)n1 +CCc1nsc(N2CCN(Cc3ccnn3C)CC2)n1 +CCN(CCC#N)C(=O)CN1CCOCC1C1CC1 +CCN(C1CCCCC1)S(=O)(=O)N(C)C(C)C +CN(CCC#N)C(=O)COc1ccc(Br)cc1F +CC(C)Oc1ccc(C#N)cc1NC(=O)c1cc(C(C)C)[nH]n1 +CCc1noc(-c2ccccc2NC(=O)COc2ccccc2C)n1 +CCc1nnc(NC(=O)CCOc2ccccc2)s1 +CCCCS(=O)(=O)NCC#Cc1ccc(N2CCOC2=O)cc1 +CC(NS(=O)(=O)c1ccc(Cl)cc1F)c1ccccn1 +COc1ccccc1-n1ncnc1-c1cnn2c(C)cc(C)nc12 +COCCOc1cccc(NC(=O)c2ccc3[nH]cnc3c2)c1 +COc1ccc2nc(NC(=O)CCNC(=O)C(C)(C)C)sc2c1 +CCN(C)C(=O)CSc1ccc(C(F)(F)F)cn1 +O=C(c1cccs1)N1CCC(c2nnc(C3CC3)s2)CC1 +CN(C)C(=O)C1CC2CN(S(=O)(=O)c3cccc(F)c3)CC1O2 +CC(=O)Nc1ccc(SCc2ccc3c(c2)OCO3)cc1 +Cc1nc2ccccc2n1CCCNC(=O)Nc1ccc(F)cc1 +CCc1cccc(NC(=O)N(C)Cc2ccccn2)c1 +Cc1nc2ccccc2n(CCOc2cccc(N)c2)c1=O +COC(=O)N1CCN(c2ncnc3c2cnn3-c2ccccc2)CC1 +CC=CCOC(=O)Cc1cc2ccccc2[nH]c1=O +CC(C)(C)OC(=O)N1CCCCC1CCOc1cnccn1 +CC1CCC(NC(=O)c2cccc(Cl)c2)CC1 +Cc1ccc(F)c(S(=O)(=O)NC(C)(CC(C)C)C(N)=O)c1 +O=C(Nc1cccc(C(=O)N2CCCCC2)c1)c1nc2ccccn2n1 +CCOC(=O)C1(C#N)C(C#N)(C#N)C12CCCCC2 +Nc1cnc(COc2ccc(Br)cc2)[nH]c1=O +CC(Cc1ccc(Br)cc1)NC(=O)Cn1cnnn1 +NC(=O)c1ccccc1OCC(=O)Nc1cccc(Cl)c1Cl +CCNc1nnc(SCC(=O)NC2CCOCC2)s1 +CCN(Cc1ccccc1C)S(=O)(=O)c1ccc2c(c1)OCCO2 +CC(C)=CCOc1cccc(C(=O)N2CCCC(c3ncc[nH]3)C2)c1 +CC1=CN(C2=NS(=O)(=O)c3ccccc32)C(C)(O)C1 +CCS(=O)(=O)N1CCCC(CCc2ccc(F)c(F)c2)C1 +Cc1ccc(C(=O)OCC(=O)Nc2cccc(C#N)c2)cn1 +CCCN(C)S(=O)(=O)c1ccc2oc(=O)ccc2c1 +O=C(NC1CCOC1=O)c1cc2ccc(F)cc2[nH]1 +Cc1cc(C)n(Cc2cc(-c3ccccc3)on2)n1 +Nc1ccc(Cl)cc1NC(=O)CCSc1ncn[nH]1 +COc1cc(NC(=O)CCNC(=O)c2ccco2)cc(OC)c1 +Cc1cc(OCCCOc2ccc(S(C)(=O)=O)cc2)nnc1C +CC(C)C(C)N(C)C(=O)c1ccc(=O)n(CCOc2ccccc2)n1 +Cc1ccc2nc(C)cc(C(=O)N(C)Cc3noc4c3CCCC4)c2c1 +CN(c1ccccc1NC(=O)NCCNC(=O)C1CC1)C1CCCC1 +CS(=O)c1ccc(C(=O)NC2CCCCNC2=O)cc1 +Cc1nnc(NC(=O)Cn2cc(-c3ccccc3)ncc2=O)s1 +O=C1CCC2(CCCN(S(=O)(=O)C3CC3)CC2)N1 +COc1cccc(C(=O)NCc2nnnn2-c2ccc(F)cc2)c1 +N#Cc1ccccc1NC(=O)c1ccc(F)c(N)c1 +Cc1cc(NC(=O)CNC(=O)c2ccc(Cl)cc2Cl)no1 +CC(OC(=O)c1cc(C(N)=O)cn1C)c1nccs1 +COc1ccccc1C1CCCN1C(=O)Nc1ccnn1C +Cc1sc(=O)n(CC(=O)NC(C)c2ccc(CC(C)C)cc2)c1C +CCOCc1ccccc1NC(=O)CN(C)C(C)=O +N#CCn1c(-c2ccc(Br)cc2)ccc(C#N)c1=O +N#Cc1ccc(C2NCCc3ccc(F)c(F)c32)cc1F +COC(=O)C1=C(C)C(C(=O)Cn2cnc3c(cnn3C)c2=O)=NC1C +COc1cc(C)c(NC(=O)Nc2cnccc2C)cc1OC +Cc1cc(Br)cnc1NCCC(=O)NCc1ccncc1 +Cc1ccc(CNc2nccc(C)n2)c(OC2CCOC2)c1 +CC(C(=O)N1CCCCC1)N1c2cccc3cccc(c23)S1(=O)=O +O=C(Cc1ccccc1)Nc1cccc(C(=O)NCC2CCCO2)c1 +O=C(Cn1cccn1)NCC#CCOc1ccc2cccnc2c1 +O=C(NC1CCCc2ccccc21)c1ccc(-n2cncn2)cc1 +CN(C)C(=O)Cc1ccc(-c2nn3cnnc3s2)cc1Cl +CC(Oc1ccccc1N)C(=O)Nc1cccc(F)c1 +COc1cccc(CC(=O)Nc2cccc(C#N)c2)c1 +NC(=O)C1CN(C(=O)c2ccc(O)c(Cl)c2)CCO1 +C#CCN(C(=O)c1cncc(Br)c1)C1CCCCC1 +O=C1Cc2cc(NC(=O)c3cccc(OCC(F)F)n3)ccc2N1 +COc1ccc(-c2csc(CNC(=O)c3ccccc3)n2)cc1C +C=CCCCN(C)C(=O)NCCC(=O)N1CCN(C(C)=O)CC1 +CC(=O)Nc1ccc2cc(-c3nc4ccccc4o3)cnc2c1 +Cc1nnnn1-c1cccc(NC(=O)NCCc2ccccc2F)c1 +CNC(=O)c1cccc(CNc2cc(Cl)ccc2C)c1 +Cc1ccc(NC(=O)CSc2nnc(NC3CC3)s2)cc1 +Cc1ccccc1NC(=O)CCC(=O)c1ccc(N)cc1 +COc1cc(CN2CCOC(c3cccnc3)C2)cc(OC)c1OC +O=C(NCC(O)c1ccccn1)C1CCN(C(=O)C2CCC2)CC1 +Cc1cc(C)c(CNC(=O)CCCOc2ccccc2)c(=O)[nH]1 +CC(NC(=O)Cn1nnnc1C(C)(C)C)c1cccc2ccccc12 +CC1CCN(c2cc(NC(=O)c3cc(C4CC4)on3)ncn2)CC1 +COCC(C)(O)CNC(=O)Nc1cccc(OC)c1 +CN(C)c1ccc(C(=O)N2CCC(NC(=O)OC(C)(C)C)C2)nn1 +Cc1nc(CCc2c[nH]c3ccccc23)nc(C)c1N +COC(=O)c1cccc(NC(=O)c2cc3cc(F)ccc3[nH]2)c1 +COC(=O)c1sc(Sc2ccccc2)nc1C +COC(=O)C(C)CNC(=O)Nc1nnc(Cc2ccc(C)cc2)s1 +O=C(NCc1nc2ccccc2[nH]1)c1cc(Cl)ccc1Cl +CC1CN(C(=O)NCc2cccnc2)CC(c2ccsc2)O1 +CC(=O)Nc1ccc(C)c(NC(=O)NCCOCC(F)(F)F)c1 +Cc1occc1C(=O)NC1CC(=O)N(CCc2ccccc2)C1 +CCC(C)C(C)NC(=O)NCc1cnc(C)s1 +O=C(NCc1cccc(S(=O)(=O)N2CCCCC2)c1)C1CC1 +CN(C)C(C(=O)NCCc1ccc2c(c1)OCO2)c1ccc(F)cc1 +Cc1cnc(C(=O)NCC2COc3ccccc3O2)cn1 +COc1ccccc1OCC(=O)NCCc1ccc(F)cc1C +COc1cc(C(=O)NC2(Cc3ccc(C)cc3)CC2)ccc1O +COc1ncccc1C(=O)Nc1ccc(-c2nc(C(C)C)no2)cc1 +CCc1ccc(C(=O)NC2(c3ccc(F)cc3F)CCOCC2)o1 +COCc1cncc2c1CCN(S(=O)(=O)C1CC1)C2 +CC(=O)Nc1nc(C(=O)N2CCC(C)Sc3ccccc32)cs1 +CCNS(=O)(=O)c1ccc2c(c1)N(C(C)=O)CC(C(C)C)O2 +Fc1ccc(C(F)(F)F)c2c1CCNC2c1ccncc1 +COc1cc(OC)c(C2CC(=O)Nc3[nH]nc(C)c32)cc1OC +CCc1cc(C#N)c(NC(=O)COCCOC)s1 +COCC(=O)NC(C(=O)NC1CCCC1)C(C)C +Cc1cc(C)n(CCNc2nccc(-c3ccncc3)n2)c(=O)n1 +Cc1nonc1NC(=O)c1ccc(F)c(COCC2CC2)c1 +O=C(c1cc(COc2ccc(F)cc2Cl)on1)N1CCOCC1 +Nc1ncnc2c1ncn2C1CC(O)C(O)CO1 +O=C(NC1CCC1)c1cc(C#CCCO)ccc1F +Cc1noc(C2CN(C(=O)Cc3ccc(SC(C)C)cc3)C2)n1 +CCS(=O)(=O)N1CCC(C(=O)N2CCC2)(c2ccccc2)CC1 +N#Cc1ccc(-c2nc(-c3cc4ccccc4o3)no2)nc1 +CC(CC#N)N(C)C(=O)Nc1cccc(NC(=O)C2CC2)c1 +CC(NC(=O)C1CC(=O)N(CC(F)(F)F)C1)C1CC1 +COc1ccc(C(=O)C(C)Sc2nnnn2C(C)C)cc1OC +CC(C)C(C(=O)OCC(F)(F)F)n1nnc(-c2ccccc2)n1 +O=S(=O)(Nc1ccc(F)c(F)c1)c1ccc(F)cc1F +Nc1cc(NC(=O)CCCSc2ncn[nH]2)ccc1F +O=C(c1ccoc1)N1CC2COCC2(COc2ncccc2F)C1 +Cc1ncsc1CN1CC2CC(CC(=O)N3CCC3)OC2C1 +CS(=O)(=O)c1ccccc1SCc1cccc(F)c1F +CCCNC(=O)CN(C)S(=O)(=O)c1ccccc1C#N +COCCOCCNC(=O)Nc1ccccc1Br +CCn1nc(C)cc1C(=O)NC1CCCCCC1C(=O)OC +O=C(NCCCN1CCOCC1)c1cc(-c2cccc(F)c2)no1 +COc1cc(O)cc2c1CCNC2c1ccccc1F +COc1ccc2c(c1)CCCN2C(=O)CSc1ncn[nH]1 +CCC(C)N(Cc1ccccc1Cl)C(=O)c1cc(C)nc(N)n1 +CC(=O)Nc1ccc(F)c(NCCCc2ccccc2)c1 +Cc1ccc(S(=O)(=O)N(C)c2cccc(O)c2)cc1 +Cn1ncnc1SCC(=O)NCc1ccco1 +CCOCCC1(C(=O)Nc2cccc(C#N)c2)CCC1 +COc1ccnc(NC(=O)c2cc(Cl)ccc2Cl)c1 +CSc1ccccc1C(=O)N1CCN(C(=O)C2CCCO2)CC1 +NC(=O)NCCCCC(=O)N1CCOC2CCCCC21 +N#CC(c1ccccc1)c1ccc(NC(=O)c2ccnnc2)cc1Cl +COCCc1n[nH]c(N)c1-c1ccc(F)cc1Cl +Cc1cc(NC(=O)Cn2nnnc2-c2ccccc2)no1 +CCCc1nc(COc2cc(C(=O)N(C)C)ccc2C)cs1 +NC(=O)C1CN(S(=O)(=O)c2cc(F)ccc2F)CCO1 +Cn1c(COc2ccc(Cl)c(Cl)c2)cc(=O)n(C)c1=O +C=CCn1nnnc1SCCOc1cccc(Br)c1 +CC(C)NS(=O)(=O)c1c(N)nc2ccccn12 +Cc1ccc(NC(=O)C2CC2)cc1NC(=O)c1cc(Cl)c[nH]1 +CNC(=O)Cn1cc(NS(=O)(=O)c2cc(F)ccc2Cl)cn1 +CC(Oc1ccc(C#N)cc1)C(=O)N1CCCC1c1ccc[nH]1 +COc1cccc(C2C(C(N)=O)=C(C)OC(N)=C2C(N)=O)c1 +Cc1ccnc2nc(C(=O)NCCNC(=O)C3CC3)nn12 +O=C(NCCOc1ccccc1)C1CC(=O)N(C2CCCCC2)C1 +CNC(=O)C(CC(C)C)NC(=O)c1cnn(-c2ccccc2F)c1C +O=C(NC1CCCCC1)c1ccc(Cn2cc(Cl)cn2)o1 +CC(=O)Nc1cccc(C(=O)Nc2ccccc2Oc2ccccc2)n1 +CC(=O)NCc1ccc(C(=O)Nc2cccc3ncccc23)cc1 +Cc1cccc(C(=O)OCC(=O)NCc2ccccc2)c1O +CC(c1ccccc1)N(C)C(=O)c1ccc2c(c1)OCO2 +O=C(CC1CCCO1)N(Cc1ccccn1)c1ccc(F)cc1 +N#Cc1nccnc1Oc1cccc(C(F)(F)F)c1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)NCC(C)C)c1C +Cc1ccc2[nH]c3c(N4CCC(C(N)=O)CC4)ncnc3c2c1 +CN(C(=O)c1cccc(N2CCCS2(=O)=O)c1)C1(C#N)CCC1 +COc1cc(COC(=O)c2ccncc2)ccc1OC(F)F +COc1ccc(S(=O)(=O)NCCc2cscn2)c(C)c1F +O=C(CNc1cccc(OCC(=O)N2CCCC2)c1)N1CCCCC1 +CNC(=O)C1CN(S(=O)(=O)c2cccnc2)CC12CCCCC2 +CCC(=O)N1CCCN(C(=O)c2cc(C(C)(C)C)nn2C)CC1 +Cc1cnn(CC2CN(Cc3csc(C(C)C)n3)CCO2)c1 +COCc1ccc(CNS(=O)(=O)c2ccc(F)c(F)c2F)cc1 +CCOc1ccc2nc(NC(=O)c3cc(C(N)=O)cn3C)sc2c1 +Nc1cc(N2CCC3(CC2)Nc2ccccc2NC3=O)nc(N)n1 +C=CCOc1ccc(C(=O)Nc2ccc(S(C)(=O)=O)cc2C)cc1 +CN(CCc1nccs1)C(=O)c1ccc(-n2ccnn2)cc1 +CCCn1nc(C(=O)Nc2cccc(C(F)(F)F)c2)ccc1=O +COc1ccc(C(=O)N(C)Cc2cc(Cl)ccc2OC)cc1 +CCc1cccc(NC(=O)CS(=O)(=O)c2cccc(OC)c2)c1 +CC(c1ccccc1)N(C)S(=O)(=O)CCc1ccccc1 +CCOc1ccc2nc(C(=O)NCc3ccc(OC)cc3)cn2n1 +COC(=O)C(NC(=O)c1ccnc(SC)c1)C(C)C +Cn1cc(CCNc2nncc(-c3ccc4c(c3)OCO4)n2)cn1 +COc1cc(C)c(C)cc1S(=O)(=O)c1ccc(C#N)cc1 +CCCOCC(=O)NCC(C)(C)c1cccs1 +O=C(NCCNS(=O)(=O)c1ccccc1)c1ccc(F)cc1 +CCS(=O)(=O)N1CCCN(C(=O)c2ccccc2)CC1 +CN(CCc1ccncc1)c1cn[nH]c(=O)c1Cl +O=C(NCCCc1ccc(Cl)cc1)c1ccncc1F +CCC(NC(C)C(=O)N1CCOCC1)c1ccccc1 +COC(=O)c1c(C)cccc1NC(=O)c1nc2nccc(C)n2n1 +CCn1cc(-c2nnc(Cc3ccc(Cl)cc3)o2)c(C)n1 +CN(C)C(=O)c1cccc(COn2nnc3ccc(Cl)cc32)c1 +COC(=O)c1[nH]c(C)c(C(=O)C(C)N(C)C(=O)C2CC2)c1C +Cc1ccc2ncc(C(=O)N(CC(C)C)C3CC3)n2c1 +CCCCN(C)C(=O)Cn1c(=O)n(CC)c(=O)c2sccc21 +CC1(C)Cc2c(c(-c3ccc(Cl)cc3)[nH]c(=O)c2C#N)CO1 +CCOC(=O)c1ccc(NC(=O)N2CCCC(C)C2)cc1 +C#CCN1CCN(CC(=O)NCCOc2cccc(C)c2)CC1 +Cc1ccc(C(C)NC(=O)CSc2nncn2C(C)C)cc1F +COc1ccc(C)cc1NCC(=O)N(C)Cc1ccccc1C +CC(NC(=O)Cn1ccnc1)c1cccc(Cl)c1 +CCn1cc(NC(=O)Cc2ccc(OC)c(OC)c2)ccc1=O +O=C(NCc1ccccc1Cn1cncn1)c1ccc2c(c1)COC2 +CN(C)C(=O)c1ccc(-c2cccc3c2CCNC3)s1 +O=C(NCC(=O)N1CCCCC1)C1CCCCC1 +CNC(=O)c1ccccc1NC(=O)Cc1cccc2ccccc12 +CCOc1ccccc1NC(=O)c1ccc(OCC)c(OC)c1 +CCOCCCNS(=O)(=O)c1ccccc1C#N +Cc1cc(C(F)(F)F)nn1CCc1nc2c3cn[nH]c3ncn2n1 +Cn1ccc(C(=O)Nc2cccc(CO)c2)cc1=O +c1cc(COC2CN(c3ccncn3)C3CCCOC23)ccn1 +CCc1nn2c(=O)cc(CNc3ccccc3C(=O)NC)nc2s1 +COC(C)(C)c1noc(-c2n[nH]c(=O)c3ccccc23)n1 +Cc1ccc(C(C)Nc2ccc(C(N)=O)c(Cl)c2)s1 +CCn1c(=O)n(-c2ccccc2C)c(=O)c2ccccc21 +COCCN1CCN(C(=O)C2(C)CCCO2)CC1=O +COC(=O)N(C)c1ccc(NC(=O)c2sc(C)cc2OC)cc1 +COc1ccc(C(=O)Cn2nc(-c3ccccc3)oc2=O)cc1 +CC(C)(C)OC(=O)N1CCC(Oc2nsc3ccccc23)CC1 +Cc1ncc(CC(=O)N2CCC(CCc3ccccc3)CC2)c(=O)[nH]1 +CCCNC(=O)CSc1nnc(-c2ccc(F)cc2)o1 +COc1cccc(C(=O)N2CCN(c3cccc(C)c3C)CC2)c1O +Cc1ccc(CN(C)Cc2cccc3c2OCO3)s1 +Nc1c(Nc2ccc(F)c(Cl)c2)ncnc1N1CCOCC1 +C=CCN(Cc1ccc(OC)cc1)C(=O)c1cccnc1 +COc1cccc(NCc2ccccc2C(N)=O)c1 +Cc1noc(CCNC(=O)C(C)Oc2ccc(F)cc2Cl)n1 +OCc1ccc(-c2nccn2Cc2cc(-c3cccnc3)no2)o1 +CNC(=O)Nc1cccc(OCC(=O)N(C)C)c1 +CCc1n[nH]c(SCC(=O)Nc2cc(-c3ccc(C)cc3)no2)n1 +CSc1ncccc1C(=O)NC(C)c1ccc(F)cc1F +CCC(NC(=O)c1ccccc1O)c1ccccc1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3ccccc3F)cc12 +Cc1nnc(O)nc1SCC(=O)Nc1cc(Cl)cc(Cl)c1 +CC1(C)CC(=O)c2cc(C(=O)NC3CCCC3)c(=O)[nH]c2C1 +CC1CC(C)CN(C(=O)CN2CCOCC2C2CC2)C1 +CCc1cccc(OCCN2CCCS2(=O)=O)c1 +Fc1ccc(Oc2ncccn2)c(Br)c1 +CC(=O)N1CCN(CC(O)c2ccccc2Cl)CC1 +COc1ccc(CCC(=O)NC(C)C(=O)N(C)C)cc1 +CN(C(=O)C1CC1c1ccccc1F)S(=O)(=O)Cc1ccccc1 +Cc1nnc(SCC(=O)c2ccccc2F)n1Cc1ccccc1 +Cc1ccc(NC(=O)Cn2ccc3sccc3c2=O)c(Cl)c1 +c1ccc(-n2nnnc2N2CCC3(CC2)OCCO3)cc1 +O=C(NC1CCCC1)c1cc(-c2cccnc2)ccc1F +Cc1oncc1-c1nc(-c2ccccc2N)cs1 +O=S(=O)(c1ccc2ccccc2c1)N(CCO)CCO +CCc1cn[nH]c1C1CCN(C(=O)CC2CN(C(C)C)CCO2)CC1 +O=S1(=O)CCCN1CCOc1c(Cl)cccc1Cl +CC(=O)NCCCC(=O)N(C)C(C)c1ccc(-n2cncn2)cc1 +Cc1cc(CN(C)CCc2cccs2)ccc1-n1cncn1 +CCOC(=O)C1CCN(c2ncnc(NC(C)CC)c2N)CC1 +Cc1noc2nc(-c3ccc(F)cc3)cc(C(=O)Nc3ccncc3)c12 +N#Cc1ccc(-c2ccc(OCC(N)=O)cc2)cc1 +Cc1csc(C2(NC(=O)Cn3cncn3)CCCCCC2)n1 +CC(=O)N1CCCN(C(=O)c2ccc(F)cc2)CC1 +Cc1nc2ccccc2c(C)c1CC(=O)n1ncc(C#N)c1N +CS(=O)(=O)c1ccccc1C(=O)Nc1ccccc1 +COc1ccc(C(=O)NCCC2CCCO2)cc1Br +N#Cc1nc(C2CC2)oc1N1CCN(C(=O)c2ccccn2)CC1 +Cc1ccc2[nH]c(CN3CCC(C(=O)NC(C)(C)C)CC3)nc2c1 +CCCNC(=O)Cc1cc(-c2ccc3c(c2)CC(C)O3)on1 +CC(=O)Nc1ccc(C(=O)CSc2nncn2C)cc1 +COc1cc2c(cc1NC(=O)CNC(C)=O)oc1ccccc12 +Cc1cc(C)cc(OCc2nc3c(s2)CCN3)c1 +Nc1ccccc1OCC(=O)Nc1ccccc1Br +COc1ccc2c(c1)CCCN2C(=O)NCc1nnc2n1CCC2 +COC(=O)Cc1cc(C2CCN(C(=O)CC3C=CCC3)CC2)[nH]n1 +COc1cc(N)c(C(=O)N(C)CCC#N)cc1OC +COc1ccc(F)cc1C(=O)N1CCc2cc(F)ccc2C1 +CCN(CC)c1ccc(C(=O)NCc2ccncc2)cc1 +CSc1ncccc1C(=O)Nc1ccc(C(C)=O)cc1 +COc1ccc2c(c1)OCC(CNC(=O)CCNS(C)(=O)=O)C2 +CN(C)C(=O)CN(C)C(=O)C1CC(=O)N(Cc2ccccn2)C1 +CCCc1nnc(SC(C)C(=O)Nc2c(C)cc(C)cc2C)n1N +O=C(NCc1ccccc1)c1ccnn1Cc1ccccc1 +Cc1ccc(Br)cc1NC(=O)c1cn2cccnc2n1 +CCn1cnnc1CCNC(=O)c1cccc2ccnn12 +CS(=O)(=O)NC1CCCN(C(C(N)=O)c2ccc(F)cc2)C1 +Cc1csc(CNC(=O)N(C)Cc2cnn(C)c2)n1 +N#Cc1ccccc1OCC(=O)NCCc1nc2ccc(F)cc2[nH]1 +Nc1ccccc1OCC(=O)NCc1ccncc1 +CCn1cc(C(=O)NCCNc2cccc(Br)c2)cn1 +Cc1csc(NC(=O)CN2CCOCC2C2CC2)n1 +OCC1(Cc2ccc(F)cc2)CCCN(c2ncnc3[nH]cnc23)C1 +COc1ccc(-c2nn3cccnc3c2C#N)cc1 +CN(Cc1nc(-c2ccccn2)no1)C(=O)COCc1ccccc1 +CC(C)OC(=O)CCN1CCN(C(=O)c2ccc(O)cc2)CC1 +CN(Cc1nc(-c2ccccn2)no1)c1ncccn1 +COC(=O)c1cccc(C(=O)NCC(C)(C)N2CC(C)OC(C)C2)c1 +COc1ccc(C(C)(C)C)cc1NC(=O)Cn1cnc(C#N)n1 +Cc1nc(C)c(C(=O)NC2CCc3nnc(C(C)C)n3C2)s1 +CCCS(=O)(=O)N1CCCC1c1ccccc1C +CCOC(=O)C(C)Sc1ccc(S(=O)(=O)N2CCCC2)cn1 +Cc1nc2ccc(NC(=O)c3ccc4cc[nH]c4c3)cc2o1 +O=C(NCc1ccccc1)C1CCCN(c2nc3ccccc3[nH]2)C1 +Nc1cnc2c(c1)c(=O)[nH]c(=O)n2CCc1ccccc1 +COC(=O)c1ccc(S(=O)(=O)NC(C2CC2)C2CC2)cc1 +CC(C)c1cc(C(=O)NCCO)nc(N2CCCC2)n1 +Cc1cc(N)ccc1NC(=O)CCN1CCCC1=O +Cn1c(SCC(=O)NCCC2CCCCC2)nnc1-c1ccco1 +COc1cc(C#N)ccc1CNc1cc(O)ccc1C +CSc1cccc(NC(=O)c2c[nH]c(=O)cn2)c1 +COCc1nc(C(=O)NCC(C)(C)c2ccncc2)cs1 +CCn1nc(C)c(NC(=O)c2nnc3ccccc3n2)c1C +CC(C)N(C)C(=O)C1CCN(C(=O)C(C)(C)c2ccccc2F)CC1 +O=C1Cc2cc(NC(=O)c3cccc4ncccc34)ccc2N1 +CN(Cc1cccnc1)c1ncc(Br)cc1N +CC(O)CC(C)CNC(=O)Nc1cccc(-n2cccc2)c1 +COc1cc(OC)cc(-c2nnc3sc(C4CCC4)nn23)c1 +COc1cccc(C(C)NC(=O)c2ccoc2C)c1 +COC(=O)c1c(C(=O)OC)c(-c2cccc(Cl)c2)n2c1CCC2 +CC(C)Cc1nnc(SCC(=O)Nc2ccccc2Cl)n1C +CC1CNc2cc(CCN3CCOCC3)ccc2O1 +CC(C)(C)CC(=O)NCC(=O)NCCc1ccsc1 +CCc1ccc(NC(=O)Cn2c(=O)c(C)nc3ccccc32)cc1 +O=c1cc(-c2ccccn2)nc(-c2ccccc2F)[nH]1 +COCC(O)CN(C)C(=O)CCC1CCCCC1 +CC1CCN(C(=O)c2ccnc(-n3ccnc3)c2)CC1 +CCC(=O)c1ccc2c(c1)N(C)C(=O)C(C)(C)CO2 +CCc1ccc(C(=O)N2CCOCC2c2c(C)n[nH]c2C)o1 +Cn1nnnc1SCCC(=O)Oc1ccc(C#N)cc1 +CCCOc1ccc(NC(=O)C(C)NC(C)=O)c(C)c1 +CCC(=O)N1CCCC(C(=O)Oc2ccc(Cl)cc2)C1 +CC(=O)N1CCc2cc(S(=O)(=O)Oc3ccccc3C#N)ccc21 +CC(C)(C)OC(=O)N1CCc2ccc(N)cc2CC1 +Cc1cc(C(=O)N2CCN(C(=O)c3ccccc3)CC2)no1 +O=C(CC1CC1)NCCC12CCOC1CCN(c1ncccn1)C2 +Cc1cn(C2CC(O)C(CO)O2)c(=O)nc1NC1CC1 +Cc1onc(-c2ccccc2)c1C(=O)N(C)CC(=O)NC(C)(C)C +COC(=O)C1(c2ccccc2)CCN(C(=O)c2ccc(C)s2)CC1 +Cn1ccnc1SCc1nc(-c2ccsc2)no1 +O=C(Cn1cc(-c2ccc(F)cc2)oc1=O)NCc1ccccc1 +Cc1cc(C(=O)Nc2ccc(C)c3cn[nH]c23)no1 +CNC(=O)c1sc2nc(-c3ccccc3)c(NCCOC)n2c1C +Cc1nc(C(=O)N2CCN(Cc3ccc4c(c3)CCO4)CC2)cs1 +O=C(COc1cccc(Cl)c1)Nc1nnc(C2CCCO2)s1 +C#CC(OC(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C)C1CC1 +CCn1cnnc1CNC(=O)NCCN(C)c1ccccc1 +Cc1cnc(NC(=O)c2c[nH]nc2-c2ccccc2F)s1 +CC(=O)c1ccccc1NC(=O)c1cn(C)nc1-c1cccs1 +CCCc1cc(=O)[nH]c(Nc2ccc(OC)cc2)n1 +CCCC1CCC(NS(=O)(=O)N(C)CCC#N)CC1 +CCN(CCC#N)C(=O)NCc1ccc(NC(=O)C(C)C)cc1 +CCOCC(=O)Nc1cc(-c2cn3cccnc3n2)ccc1OC +CC(=O)Nc1ccc(C(=O)NCc2nc3ccccc3s2)s1 +CCCc1nn2c(CO)c(-c3ccc(N(C)C)cc3)nc2s1 +COc1nn(C)cc1C(=O)N1CC(c2nc(-c3ccco3)no2)C1 +Cc1cc2c(SCCC(=O)Nc3ccc(F)cc3)ncnc2s1 +COC(=O)c1[nH]c2c(c1N)C(=O)CC(c1ccc(C)s1)C2 +Cc1cc(C(=O)N2CCCC2c2ccccn2)c(C)s1 +OCC1NCCc2cc(Br)c(Cl)cc21 +Cc1ccc(C)c(NC(=O)C2(C)Oc3cccnc3NC2=O)c1 +CCCCc1nc(CS(=O)(=O)c2ccc3ccccc3c2)no1 +Cc1n[nH]c(SCC(=O)N2CCc3ccccc32)n1 +COc1ccccc1C(=O)OCCN1CCOCC1 +CC(C)Cn1cc(NC(=O)c2cccc(-c3ccoc3)c2)cn1 +O=C(Nc1ncccc1O)c1ccc(OC(F)(F)F)cc1 +CS(=O)(=O)c1ccc(C(=O)NC2CCCCC2C(F)(F)F)cc1 +Cc1c(NCc2ccsc2)cccc1S(N)(=O)=O +CCOC(=O)N1CCN(c2ncc(Cn3cccn3)s2)CC1 +CC(=O)N1CCCC(Cc2ccnc(-c3ccccc3)c2)C1 +Cc1noc(COCC(=O)N(Cc2cccnc2)C(C)C)n1 +CCOc1ccc(NC(=O)c2ccc(C)[nH]c2=O)cc1OC +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1cnc(C(C)(C)C)nc1 +Cc1cccnc1NC(=O)COc1ccc2ccccc2c1 +c1cncc(CCNc2cnc3ccccc3n2)c1 +O=C(c1ccccc1)C(N1CCCCC1)n1nnc2ccccc21 +O=S(=O)(NCc1cccc(Cl)c1)c1cn[nH]c1 +N#Cc1cccc(CN2CCNC(=O)C2c2cccs2)c1 +CCSc1ccc(C(=O)N2Cc3ccccc3C(O)C2)s1 +Nc1ccc(-c2ccc3c(c2)CCCC3)n(C2CC2)c1=O +Cc1c(-c2ccncc2)n[nH]c1NC(=O)c1ccc2c(c1)nnn2C +O=C(COC(=O)c1cc(=O)c2ccccc2o1)NCC1CCCO1 +CCc1ccc(S(=O)(=O)N(CC)CC)cc1N +CCOc1cc(S(=O)(=O)N2CCCCC2)c(OCC)cc1C +Cc1cncc(NC(=O)C(c2ccccc2)N2CCC(O)CC2)c1 +Cc1nc(C(F)(F)F)ccc1C(=O)NCCCO +COC(=O)Cn1c(CNC(=O)c2ccccc2C)nc2ccccc21 +CCOCCN(CC)C(=O)c1ccc(-n2ccnn2)cc1 +O=C(Cn1cnc2ncccc2c1=O)NCc1ccccc1Cl +COCCCNS(=O)(=O)c1cc(Br)cnc1N +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)N2CCCC(C)C2)c1 +Cc1cc(NCCN2CCOCC2)n2nc(C(F)(F)F)nc2n1 +CC(Sc1nc(-c2cccs2)n[nH]1)C(=O)NCC1CCCO1 +Cc1cccc(CNC(=O)c2cnc3sccn3c2=O)c1 +O=C(NCCNc1cccnc1)C1CC(=O)N(C2CC2)C1 +O=C(NCCc1cnn(-c2ccccc2)c1)c1ccc2c(c1)OCO2 +NS(=O)(=O)c1ccccc1C(=O)c1cccs1 +O=C(NCCn1ccc2ccccc21)c1nc2ccccn2c1F +Cn1cc(C(O)CNC(=O)CCC2CCCC2)c2ccccc21 +CC(NC(=O)C1CC(=O)Nc2cc(F)ccc21)C1CCCO1 +COCc1nc(C)c(C(=O)NCc2nc(C)sc2C)s1 +Cn1cc(S(=O)(=O)Nc2ccc(F)cc2)cn1 +COc1cccc(-c2nnc(NC(=O)c3cc(C)n(C(C)C)n3)o2)c1 +COc1cccc2sc(NC(=O)c3ccc(C)[nH]c3=O)nc12 +CCNC(=O)c1cccc(NS(=O)(=O)c2cc(C)ccc2C)c1 +CC(NS(N)(=O)=O)c1ccc(Cl)cc1Cl +CN(C)c1ncccc1-c1nc(C2CCCC2)nn1CCO +CC(=O)Nc1ccc(C(=O)CSc2ccc(C)cc2)c(F)c1 +N#Cc1cn(Cc2ccccc2)c2ccccc2c1=O +O=C(Nc1cnn(-c2ccccc2)c1)C1COc2ccccc2C1 +Cc1ccc(C)c(N2CC(C(=O)Nc3nc(C)cs3)CC2=O)c1 +Cc1c(C(=O)NCC2CCOC2)[nH]c2c1C(=O)CC(C)(C)C2 +c1ccc(-c2noc(N3CCN(c4nccs4)CC3)n2)cc1 +Cc1ncoc1C(=O)NCc1ccccc1Cn1cccn1 +Cc1nn(C)c(C)c1-c1cc(C(=O)N(C)Cc2cccc(F)c2)[nH]n1 +O=C(CCc1ccc(F)cc1)N1CC(C(=O)N2CCCCC2)C1 +c1nc2ccc(C3NCCc4ccc5[nH]ccc5c43)cc2[nH]1 +COc1ccccc1-c1c(C#N)nnn1-c1ccccc1F +Cc1nn(CCOc2ccccc2)c(=O)n1-c1c(F)cccc1F +Cc1ccc(CN2CCOC3C(OCC(=O)N(C)C)CCC32)o1 +CCNC(=O)c1nn(-c2cccc(C(F)(F)F)c2)cc1OC +COC(=O)NCC(=O)N(C)c1ccc2ccccc2c1 +O=C(CCCc1cc(F)ccc1F)NC(c1nccs1)C1CC1 +O=C(NCc1ccncc1)Nc1ccc(C(=O)NC2CC2)cc1 +CCOCC(O)CN1CCN(c2cccc(C)c2C)CC1 +CC(C)N(C)C(=O)C1CCN(C(=O)CCCNC(=O)C2CC2)CC1 +CC(O)(CNC(=O)Cc1cccs1)c1cccs1 +CN(Cc1cccs1)C(=O)Cn1cnc2sccc2c1=O +CCCNC(=O)CSc1ccc(-c2nc(CC)no2)cn1 +CCC(CC)C(=O)NCC(=O)Nc1ccc(F)c(F)c1F +N#CC(c1c[nH]c2ccccc12)N1CCCCCC1 +COCCc1noc(CNc2ccn(-c3ncccc3Cl)n2)n1 +CN(CCC#N)C(=O)c1ccc(NC(=O)c2ccccc2)cc1 +C=C(C)COc1cc(C(=O)NCc2ccccc2)ccc1N +Cc1nn(C)c(C)c1CC(=O)N1CCC(Cc2cccc(F)c2)CC1 +CCc1ccc(C(O)CCc2nc(C)c(C)s2)cc1 +O=C(CCSc1ccccn1)NCC(=O)Nc1cccnc1 +N#CC1(NC(=O)CSc2ccc(Cl)cc2)CCCC1 +C#CCOC(=O)C1CCCN(C(=O)Nc2ccccc2)C1 +CC(C)CC(NS(C)(=O)=O)C(=O)NC1CCOc2ccccc21 +Cc1ccc(NC(=O)CCn2c(=O)[nH]c3ccsc3c2=O)cc1F +CCOc1ccccc1NC(=O)NCCCN1CCCCCC1=O +CC(C)(O)CCc1cccc(C(=O)NCC(C)(C)CO)c1 +Cc1cc(C(=O)NC(C)c2cccc(N3CCCC3)c2)[nH]n1 +Cc1cc(C)cc(NC(=O)c2ccc(Cn3cncn3)cc2)c1 +CC(=O)c1ccccc1OCC(=O)NCc1ccccc1Cl +CN(CCOc1ccccc1)C(=O)c1cnn(-c2ccc(F)cc2)n1 +COc1ccc(Cn2nnnc2SCC(=O)NC(C)(C)C)cc1 +O=C1NCCN1C1CCN(c2nccc(C(F)(F)F)n2)CC1 +CC(Cc1c(F)cccc1F)NCc1ccco1 +CCCN(CC(=O)OC)C(=O)c1cc(C)c(C)s1 +CC(NCC(F)(F)F)(C(N)=O)c1ccc(S(C)(=O)=O)cc1 +CC(C)N1CC(C(=O)NCCCn2ncc3ccccc32)CC1=O +Cc1cccc(CN(C(=O)Cn2cnc3ccccc3c2=O)C2CC2)c1 +CC(=O)N1CCN(C(=O)N(C)C)CC2(CNC(=O)C2)C1 +CC(C)CCNC(=O)Nc1ccc(OCC(F)(F)F)nc1 +O=c1c2ccccc2ncn1-c1cccc(Cl)c1 +CCOc1ccc(S(=O)(=O)N(C)C(C)CC)cn1 +CCCCn1nc(C(=O)Nc2ccc(OC(F)F)cc2)ccc1=O +CC(CO)NC(=O)c1cc2cc(Cl)ccc2o1 +CN(CC(=O)NC1CC1)C(=O)c1ccc(Cl)cc1 +CNc1cccc(C(=O)N(C)Cc2ccsc2)n1 +CC(=O)Nc1nnc(Cc2ccc(C(C)C)cc2)o1 +CC1CCC(C)N1C(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +Cc1ccc(C(O)CNCc2cccnc2)c(C)c1 +CC1Cc2cccc(N)c2N(C(=O)OC(C)(C)C)C1 +Cc1ccc(C(=O)CCC(=O)Oc2ccc3cn[nH]c3c2)s1 +CCn1cc(CN(C)S(=O)(=O)c2ccc(C)c(C)c2)cn1 +O=C(CCc1ccccc1)Nc1ccc2c(c1)OCO2 +CCCN1CCc2nc(NC(=O)c3ccc(C#N)cc3)sc2C1 +CSc1cc(C(=O)NCc2ncc(-c3ccccc3)o2)ccn1 +CCc1ccc(NC(=O)c2cnc3ncnn3c2C)cc1 +CC(Cc1cc(=O)[nH]c(NCc2ccc(F)cc2)n1)n1cccn1 +CCOC(=O)c1cncc(C(O)c2ccccc2)c1 +COc1ccc(C#CCNC(=O)NCc2ccc(F)cc2)cc1 +Cc1nc(C)n(CC2CCCCN2c2ncnc3ccsc23)n1 +COCC(=O)N1CCN(c2nccn2-c2ccccc2F)CC1 +CCOc1ccc(NC(=O)CCC2CCCO2)cc1Cl +CCOc1ccc(-c2nc(-c3ccco3)cs2)cc1N +Cc1cc(C(=O)NC2CCN(C(C(N)=O)c3ccccc3)CC2)no1 +CNC(=O)CNC(=O)CNC(=O)c1cccs1 +CSc1ccc(CN(C)C(=O)NCCc2ccccn2)cc1 +O=C(Cc1cc2ccccc2[nH]c1=O)NCC1(c2ccccc2)CC1 +OC1CCC(Nc2ncnc3sc4c(c23)CCCCC4)CC1 +CCSc1cccc(C(=O)Nc2c(C(N)=O)oc3ccccc23)c1 +COc1ccccc1N1CCN(CC(=O)NCc2cccs2)C1=O +CC(C)c1cc(C2CCCN2C(=O)c2cc(C3CC3)on2)on1 +CCOC(=O)CSc1ncnc2c1cnn2-c1ccccc1 +Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CC(C)CC3)cc1 +O=C(NCC1COC2(CCCCC2)O1)c1nc2ccccc2s1 +CC(Sc1ncc2ccccn12)C(=O)NCc1ccccc1F +CC1(C)C(Cc2cc(CO)on2)CC1NC(=O)c1cccnc1 +O=C(CCNC(=O)N1CCCC(O)C1)NC1CCCCC1 +CCOC(=O)Cn1nc(C)c2c1N=C(O)CC2c1cnn(C)c1 +CC(=O)NC1C(Oc2ccc3ccccc3c2)OC(CO)C(O)C1O +CC(C(=O)Nc1ccc(C#N)cc1)N1CCN(c2nccs2)CC1 +O=C(NCC(c1cccnc1)N1CCOCC1)Oc1ccccc1 +Cn1ncc2c1ncn1nc(-c3ccc(OC(F)F)cc3)nc21 +O=C(c1ccncn1)N1CC(OCc2ccccn2)C2OCCCC21 +CC(C)CNC(=O)COc1ccc(C(=O)NC2CCCC2)cc1 +C#Cc1cccc(NC(=O)c2cccnc2OC)c1 +CC(C)(C)C(=O)NCCc1nc2ccccc2s1 +CCNC(=O)C(C)NC(=O)CN1CCc2ccccc21 +CC(=O)N1CCC(c2nccnc2N2CCOCC2)CC1 +Cc1n[nH]c(C)c1N1CCN(C(=O)Cc2ccccc2)CC1 +O=C(CCSc1nnc(COc2ccccc2)o1)N1CCCCC1 +COc1ccc(C(=O)Nc2ccc(C)c(-n3cnnn3)c2)cc1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cccc(-c4ccoc4)c3)cc12 +CNC(=O)c1ccc(NC(=O)C2CCN(C(=O)C(C)(C)C)CC2)cc1 +Cc1nnc2n1CC(NC(=O)c1ccc3c(c1)OCO3)CC2 +CC(C)C(NC(=O)c1ccnc2c1OCO2)C(=O)N1CCCC1 +CCCSc1nnc(NCC(=O)c2ccccc2)s1 +N#CCSc1n[nH]c(C=Cc2ccc(F)cc2)n1 +O=S(=O)(NC1CCCCCC1)c1cnn(-c2ccccc2)c1 +O=c1oc2ccc(CO)cc2n1Cc1cccc(F)c1 +CCOc1ccccc1OCc1ccc(C#N)cc1F +CCc1noc(CN(C)C(=O)Nc2cnccc2C)n1 +CC(NC(=O)Nc1ccc(F)c(C#N)c1)C(=O)N1CCCCC1 +Cc1occc(=O)c1OCc1ccccc1Cl +O=c1cc(CSc2ccc(Cl)cc2)[nH]c(=O)[nH]1 +CCNC(=O)C(C)Sc1nc(-c2ccco2)nc2ccccc12 +COc1ccc(C(=O)N2c3ccccc3CC2C)nn1 +Cc1ccc(OCCC(=O)OCC2CCC(=O)N2)cc1C +CC(C)CN(Cc1cccc(Cl)c1)C(=O)c1cc(N)ccn1 +COC(=O)c1ccc2nc(NC(=O)c3ccn(C(C)C)n3)sc2c1 +COc1ccc(CNC(=O)Cc2coc3cc(C)ccc23)cc1F +CC(CC1CCCC1)C(=O)N1CCN(C(=O)N(C)C)CC1 +CC(=O)Nc1cccc(OCCNC(=O)c2sccc2C)c1 +COc1ccccc1-c1cc(C(=O)Nc2ccc3c(c2)OCO3)no1 +CN(CCC(F)(F)F)C(=O)c1ccc(Oc2ccccc2)nc1 +CCN(Cc1noc(C(C)C)n1)c1ccccc1C +COC(=O)c1c(NC(=O)c2cccnc2)sc2c1CCCC2 +CCN(CC)C(=O)CN(c1ccc(Cl)cc1C)S(C)(=O)=O +COC(=O)c1cccnc1N1CCCC2(CCC(=O)N(C(C)C)C2)C1 +CC(C)N(CCc1nccs1)C(=O)c1cccc(-c2ccoc2)c1 +CCOC(=O)C(C)NC(=O)C1CC(=O)N(c2ccc(CC)cc2)C1 +Cn1cc(NC(=O)c2csc(-c3ccc(Cl)cc3)n2)cn1 +CCc1noc(C2CCCCN2C(=O)Cc2ccccc2)n1 +Cc1cccc(NS(=O)(=O)c2ccc(CCCO)cc2)c1 +O=C(CCc1ccc2c(c1)OCO2)N1CCC2(CC1)OCCCC2O +Cc1n[nH]c(C)c1C(=O)Nc1cccc(C(=O)Nc2ccccn2)c1 +Cc1sc(-n2cnnn2)c(C(=O)NCCC2=CCCCC2)c1C +COC(=O)C1CCN(C(=O)CSc2ccc(F)cc2)CC1 +CC(C)(C)c1ccc(N2CCC(NC(=O)Cn3cccn3)CC2)cc1 +COc1ccc(CNc2cnccc2C#N)c(F)c1 +Cc1cccc(OCC(=O)NCc2c[nH]nc2C)c1C +COC(=O)NCC1(c2cccs2)CCOCC1 +CC(Oc1ccc(CO)cc1Br)C(=O)NC(C)(C)C +CCOc1ncccc1NC(=O)NC(C)c1ccncc1 +Cc1cc(C)c(NC(=O)CNC(=O)CCC2CCCC2)c(C)c1 +CCn1ccc2c(ccn2CC(=O)Nc2ccc(C)cc2)c1=O +O=C(CCn1ccc(=O)[nH]c1=O)Nc1cccc(-c2cc[nH]n2)c1 +Nc1cnn(-c2cc(Cl)cc(Cl)c2)c(=O)c1 +CC(C)CCNC(=O)C1CCCN(c2ccc3nnnn3n2)C1 +O=C(Nc1cccc(F)c1)c1cc(-c2ccc(F)cc2)[nH]n1 +Cc1cc(C)n(Cc2c(C(=O)NCc3cccs3)noc2C)n1 +CCN(CC1COc2ccccc2O1)C(=O)c1ccc(=O)n(C)n1 +Cc1nc(CNC(=O)Nc2cc(C(N)=O)ccc2C)c(C)s1 +O=C(NCc1ccccc1CO)NCC1CCCC1 +CN(C)C(=O)c1ccc(C(=O)OCCNc2cccnn2)cc1 +CN(c1ccc2ccccc2n1)S(=O)(=O)CC1CCOC1 +Oc1c(Cl)cc(Cl)c2c1CCNC2c1cc[nH]n1 +Cc1nc(-c2ccccc2C)n(CC(=O)NC(C)C)n1 +CC(CO)CNC(=O)NCc1cccc(Cl)c1 +CC(C)CN1C(=O)CCC2CN(C(=O)c3ccc(F)cn3)CCC21 +NC(=O)NCCCCC(=O)Oc1cc(Cl)ccc1Cl +Cc1c(CNC(=O)Nc2cc(F)c(F)cc2F)cnn1C +CC(C)c1nnc(C(N)c2cccc(Cl)c2F)o1 +Cc1c(NC(=O)c2cccnc2)cccc1S(=O)(=O)NC(C)(C)C +CCn1nc(-c2ccc(C)o2)nc1-c1ccc2c(=O)n(C)cnc2c1 +COc1ccc(C(C#N)CC(=O)Nc2ccc(C#N)cc2)cc1 +CC(C)N(CCC#N)C(=O)c1ccc(Cl)cc1O +CCOc1ccc(NC(=O)Cn2nc3ccccn3c2=O)cc1F +O=C(CCC1CCCOC1)N1CCC(Oc2cccc(Cl)c2)C1 +CC(C)Nc1nc(N2CCCC2)nc2c1cnn2C +CCC(C)c1ccc(S(=O)(=O)NCCOC)cc1 +COc1ccc(OC)c(C(=O)CC2(O)C(=O)Nc3c(C)cccc32)c1 +Cn1c(C(=O)NCC(=O)N2CCC(C(N)=O)CC2)cc2occc21 +O=C(Nc1nnc(-c2ccccc2)o1)c1cc2ccccc2o1 +Cc1nc(C(=O)NCCCN2CC(C)OC(C)C2)cs1 +CCNC1=NS(=O)(=O)c2cc(CC)ccc2N1 +C=CCNC(=O)NCCc1coc(-c2ccc(C)cc2)n1 +CC(C)Cn1cncc1CNC(=O)c1cccc(-n2cnnc2)c1 +Cc1cc(C)n(C)c(=O)c1C(=O)NCC1COc2ccccc2C1 +NC(=O)C1(CNC(=O)C2CC2c2ccccc2F)CCOCC1 +COCCOC(=O)C(C)NC(=O)c1cccc(Cl)c1Cl +CC(NC(=O)c1cc2c(=O)n(C)ccc2n1C)c1ccccc1 +COC(=O)C(CNC(=O)c1csc(C)n1)Cc1ccc(O)cc1 +OCC1CCCN1c1cc(N2CCN(c3ccccc3)CC2)ncn1 +COC(=O)CC1C(=O)NCCN1C(=O)CCOc1ccc(C)cc1 +CCC(CC)C(=O)N1CC2CCc3cn(CCNC(C)=O)nc3C2C1 +O=C1NCCN(C(=O)c2ccoc2)C1c1ccccc1C(F)(F)F +CCc1nc(CC(=O)N2CCCC(n3cccn3)C2)cs1 +COc1ccc(CCC(=O)Nc2ccc(O)cc2)cc1 +COc1ccccc1OCC(=O)N1CCN(CCCO)CC1 +CCC(=O)N1CCN(c2nc(C3CC3)nc3sc(C)c(C)c23)CC1 +Cn1ncnc1-c1ccnc(NC2(c3ccccc3)CC2)n1 +Cc1ccc(F)c(S(=O)(=O)NCC(C)(C)NS(C)(=O)=O)c1 +Cc1nc(C2CCN(C(=O)c3ccc(F)c(Cl)c3F)CC2)n[nH]1 +COc1ccc(Br)c(C(=O)NCCc2ccco2)c1 +Cc1ccc(CNC(=O)NCC(=O)Nc2ccc(C)cc2O)cc1 +CCOC(=O)C(C)N1CCN(CC(=O)N2CCCCC2)CC1 +Cc1nn(C)c(C)c1CNc1ccc(-c2nnc3n2CCCC3)cc1 +CCN(CC(O)COc1ccccc1Cl)S(=O)(=O)O +COc1ccc(CCOC(=O)Nc2ccccc2)cc1OC +CCCOc1ccc(CNC(=O)c2cn3cccnc3n2)cc1OC +COc1cccc(C(=O)N2CCN(C3(C(N)=O)CCCCC3)CC2)c1 +COC(=O)c1sc2ncn(CC(=O)N3CCCC3)c(=O)c2c1C +Cc1cccc(NC(=O)CCCS(=O)(=O)c2ccccc2)c1 +CN(C)S(=O)(=O)c1ccc(C(=O)Nc2ccc(F)cc2N)cc1 +C=CCNC(=O)CN1CCN(C(=O)C(C)(C)c2ccccc2C)CC1 +Cc1ccc(NC(=O)CCn2[nH]c(=O)ccc2=O)cc1Cl +NC(=O)C(c1ccccc1)N1CCC(NC(=O)CC2CCCC2)CC1 +COc1ccc2c(c1)cc(-c1nc(C3CCOC3)no1)n2C +CC(NC(=O)NC1CCSc2ccc(Cl)cc21)C1CCCO1 +NC(CO)c1nc(-c2ccc3ccccc3c2)cs1 +CCc1nc(CNc2cc(C(F)(F)F)ccc2NC(C)=O)no1 +COc1ccccc1CNC(=O)Cn1c(-c2ncccn2)noc1=O +Cc1ccc(-c2nc(CNC(=O)Cn3cnnn3)co2)cc1 +O=C(NCCc1ccccc1)c1nc(Cc2c[nH]c3ccccc23)no1 +Cc1cc(C)nc(Nc2nc(CC(=O)Nc3ccccc3)cs2)n1 +CC(C)(CCC#N)CNc1cnn(Cc2ccc(Cl)cc2)c1 +COc1ccccc1OC(C)C(=O)Nc1ccccc1C +CCCCN(C)S(=O)(=O)N1CCc2c(N)cccc2C1 +CC(=O)NCCNC(=O)NC(C)c1ccc(Cl)cc1 +Cc1cccc(C(=O)NC(C(=O)N2CCCCCC2)C(C)C)c1 +O=C(Cc1ccc[nH]1)NCc1cccc2cccnc12 +CCOC(=O)C1CCC(=O)N1c1cccc(C)c1C +Cc1nc(C(NC(=O)c2ccnc(N(C)C)c2)c2ccccc2)n[nH]1 +COC1CCCCC1OC(=O)Cc1cccc2cccnc12 +COc1ccc(C(=O)Cn2nc(-c3cccs3)oc2=O)c(OC)c1 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+CCC1CN(CC(=O)Nc2nccs2)c2cc(N)ccc2O1 +CS(=O)(=O)NCC1CCCN(C(=O)c2ccc3cc[nH]c3c2)C1 +COC(=O)C1C2C=CC3(CN(CC(O)CO)C(=O)C13)O2 +CC(C)(C)OC(=O)N1CCC(Oc2ccccc2Cl)CC1 +COCc1cc(N(C)CCc2c(C)n[nH]c2C)ncn1 +CCC(=O)N1CCCN(C(=O)NCC2CCCC(C)C2)CC1 +COC(=O)C1CCN(C(=O)c2cc3c(s2)CCC3)c2ccccc21 +CCOC(=O)CCCC(=O)c1c(F)cccc1Cl +Cc1cc(S(C)(=O)=O)ccc1NC(=O)c1ccoc1 +Cc1n[nH]c(=O)c(C(=O)N2CCN(Cc3c(C)noc3C)CC2)c1C +OCCNc1nc(NCc2cccnc2)nc2nccnc12 +Cc1ccc(NS(=O)(=O)c2cn(C)nc2N)c(Cl)c1 +O=C(NCc1cccc(O)c1)c1c[nH]c2ccccc12 +COc1cccc(C(=O)N2Cc3ccccc3N(C)CC2C)c1F +O=C(NC12CC3CC(CC(C3)C1)C2)c1ccc(-n2cncn2)nn1 +CCCC(C)NC(=O)C(C)Nc1ccc(N2CCOC2=O)cc1 +CCC(c1ccncc1)N(C)S(=O)(=O)c1cccc2nonc12 +CC1CN(Cc2cc(=O)c(O)cn2Cc2cccnc2)CC(C)O1 +Cc1ccc2sc(C=Cc3cnn(C)c3)nc2c1 +O=C(NCC#Cc1ccccc1C(F)(F)F)c1ccc(=O)[nH]c1 +C#CCN1CCN(C(=O)NC(c2ccc(F)cc2)C2CCC2)CC1 +Cc1cc(C)c(C(=O)NCc2ccc(F)cc2C(F)(F)F)c(=O)[nH]1 +Cc1ccc(Sc2ncnc(N(C)C)c2N)cc1 +CCc1nc(CC(=O)N(C)CCOc2cccc(C)c2)cs1 +Cc1cc(C(C)NC(=O)CN(C)c2ncnc3[nH]cnc23)c(C)o1 +NS(=O)(=O)c1cccc(S(=O)(=O)NCc2ccoc2)c1 +CN(C)C(=O)CNc1cccc(OCc2cccc(C#N)c2)c1 +COc1cc(C(C)=O)ccc1OC(C)C(=O)N(C)c1ccccc1 +CC1CCN(C(=O)c2cc(NC(=O)C3CC3)n(C)n2)CC1 +CCNC(=O)c1ccc(CNC(=O)NCc2cnc(C)s2)cc1 +COC(=O)c1ccc(Oc2cccc(N)c2)cc1C(=O)OC +Cc1cc(NC(=O)CC(C)C)ccc1N1CCCCC1=O +O=c1[nH]c(=O)n(CCCc2ccc(C(F)(F)F)cc2)cc1Cl +CCc1nc(C(=O)N2CCOC3CCCCC32)c[nH]1 +CC1(C)CC(C2N3CC4(C)CN2CC(C)(C3)C4=O)CCO1 +CNC(=O)c1ccc(NC(=O)NCc2cccc(F)c2)cc1Cl +O=C(COc1cccc(Cl)c1)N(Cc1ccco1)Cc1ccco1 +CSc1cc(C(=O)NCCOc2cccnc2)ccn1 +O=C(c1cccc(OCC(F)F)n1)N1CCCC2CCCC21 +N#CC(C(=O)C1CCCC1)c1nc2ccccc2o1 +O=C(Nc1ccncc1)N1CCC(c2nc(-c3ccccc3)n[nH]2)CC1 +CCOc1cc(NC(=O)C2CCOCC2)ccc1OC +C#CCN1CCC(C(=O)OC(c2ccccc2)c2ccccn2)CC1 +CCc1nnc(CN(CC)C(=O)c2cc3c(nc2OC)CCC3)o1 +Cc1c(N)c[nH]c(=O)c1C(=O)NCc1ccccc1 +Nc1n[nH]c2cc(-c3ccc(Cl)cc3Cl)[nH]c(=O)c12 +COc1ccc(OC)c(-c2nnc(NC(=O)c3ccco3)o2)c1 +FC(F)c1nnc(NCc2cccc(-c3cccnc3)c2)s1 +Cc1oc(-c2ccco2)nc1CC(=O)NCC(C)(O)c1ccsc1 +COc1ccc(CC(=O)Nc2ccc(N)c(F)c2)cc1 +Cc1nc(CSc2nnc3sc4ccccc4n23)oc1C +COc1cc(C)c(C(C)NC(=O)c2ccccc2)cc1OC +Cc1cc2cc(NC(=O)c3ccc(C#N)cc3)ccc2[nH]1 +Cc1cccc(OCCC(=O)NCc2ccc(-n3cccn3)nc2)c1 +COC(=O)c1c(C2CC2)csc1NC(=O)C1CCC(F)(F)CC1 +Cc1n[nH]c(CNC(=O)C2CC(NC(=O)C(C)(C)C)CN2C)n1 +CC(C)CC(Nc1ncccn1)Nc1ncccn1 +C#CC(OC(=O)C1CCCN(C(=O)C(C)(C)C)C1)C1CC1 +Cc1[nH]c2ccccc2c1C(=O)N1CC(C)OC(C)C1 +COc1ccccc1SCC(=O)c1ccc2c(c1)OCO2 +CC(=O)N1CCc2c(oc(N)c2C(=O)c2cccnc2)C1 +N#CCc1ccc(NC(C(=O)N2CCCC2)c2ccccc2)cc1 +CC(C)n1c(=O)n(CC(O)c2ccccc2)c2ccccc21 +CCOc1ccccc1NC(=O)NCC1(O)CCOc2ccccc21 +Cc1ccc(NC(=O)C2CCCO2)c(-c2nc3ccccc3[nH]2)c1 +Cc1cc2c(c(C)c1N)NC(=O)C(c1ccc(F)cc1)O2 +COCCNC(=O)c1c(C)noc1-c1ccc(C(C)(C)C)cc1 +O=C(Nc1ccc(F)cc1)c1noc2ncnc(N3CCOCC3)c12 +N#Cc1ccccc1C(=O)NCCC1CN(Cc2ccco2)CCO1 +CCc1nn2c(CNC(=O)c3cccc(N(C)C)c3)c(C)nc2s1 +COC(C)(C)c1noc(CCNS(=O)(=O)c2ccccc2)n1 +O=C(CCC(=O)Nc1nccs1)NCC1(c2ccccc2)CC1 +COC(=O)c1sc2ncccc2c1NC(=O)c1ccc(C)cc1 +Cc1cc(C(=O)NC2CCN(S(C)(=O)=O)CC2)c(C)n1C(C)C +CCCCn1c(=O)[nH]c(=O)c2c1nc(N)n2CC +CCOc1cc(C(=O)N(C)Cc2ccccc2Cl)ccc1OC +Cc1nn(C)c(C)c1CN(C)c1nc(C2CC2)nc2c(C)nn(C)c12 +Cn1nc2n(c1=O)CCN(C1CCCc3ccccc31)C2 +Cc1nn(C)c(C)c1CCC(=O)NCCNC(=O)c1ccc(O)cc1 +Cn1c(C2COC2)cc2ccc(Br)cc21 +COc1ccc(CNC(=O)N2CCCC(O)C2)cc1 +Cc1onc(-c2ccccc2)c1C(=O)OCC(=O)N1CCC(C)CC1 +CN(C)c1nc(CNc2ccccc2C(F)(F)F)ns1 +Cc1cc(C)nc(NC(=O)NC2(c3noc(C)n3)CCCC2)c1 +Cc1cc(C)n(-c2ccccc2NC(=O)NC2(CCO)CCC2)n1 +CC(C)(C)c1n[nH]c(C2CN(Cc3noc(C4CC4)n3)CCO2)n1 +O=C(NCc1nnc2ccccn12)N1CCc2c(F)ccc(F)c2C1 +Cc1noc(C)c1S(=O)(=O)NCc1csc(C2CC2)n1 +O=C(CCCN1CCOC1=O)Nc1ccc(F)c(Cl)c1 +COC(=O)c1c(NC(=O)NCCc2ccccc2)sc2c1CCC2 +CC(=O)NC(C)(C)c1noc(CN2C(=O)CSc3ccccc32)n1 +O=C(NCc1ccc(CN2CCOCC2)cc1)c1ccc(=O)[nH]c1 +Cc1onc(-c2c(F)cccc2Cl)c1C1=NCCO1 +Cn1cc(NS(=O)(=O)c2ccc3c(c2)NC(=O)CO3)cn1 +CCOC(=O)c1ccoc1Cn1cnc2c1c(=O)n(C)c(=O)n2C +O=C(NCc1ccncc1)Nc1ccc(NC(=O)C2CCCO2)cc1 +Cc1ccc(CC(=O)N(C)Cc2ccc(C)s2)cn1 +COCCCNc1nc2nonc2nc1NC1CCC1 +O=C1COc2cc(NC(=O)NC3CCCc4occc43)ccc2N1 +CC(C)NC(=O)C(NC(=O)c1c(F)cccc1F)C(C)C +CCCOc1ccc(Cl)cc1NC(=O)c1ccc(C(N)=O)cc1 +NC(=O)c1cc(C2CCCN(C(=O)C3CC3c3ccccc3)C2)n[nH]1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1ccco1 +CC1CCC(NC(=O)N2CCC(C(=O)N3CCCC3)CC2)CC1 +COCCC(=O)Nc1cnc(N2CCCC2)nc1 +COc1ccn(C2OC(=O)C(C)(C)C2=O)c(=O)n1 +Cc1csc(=O)n1CC(=O)OCC(=O)NC1CCC(C)CC1 +CCOc1ccccc1C(CC(=O)N1CCCC(O)C1)NC(C)=O +CC(=O)N(CCc1ccccc1)CC(=O)N1CCC(C)CC1C +O=C(NCc1ccccn1)c1ccc2c(c1)OCO2 +COCc1nc2n(n1)CC(CC(=O)OC)C(=O)N2 +Cc1cc(C)n(CC(C)CNC(=O)NCc2ccc3c(c2)CCC3)n1 +COCC(=O)c1ccc(OC(C)C)c(OC(C)C)c1 +CCOC(=O)NCCC(=O)Oc1ccc(C)cc1 +CC(C)n1ccc(C(=O)N(C)CCc2ccccn2)n1 +COc1cc(O)ccc1-c1c(C#N)c(N)nc2c1CCc1[nH]ccc1-2 +CN(C)C(=O)C1CCCN1C(=O)C1COc2ccc(F)cc2C1 +CCc1ccc(C(C)Nc2cc(C)nc3ncnn23)cc1 +CCNC(=O)Cn1cccc1-c1nc(-c2ccc(Cl)cc2)no1 +CC(=O)Nc1cc(NC(=O)C(C)Sc2ccccn2)ccc1Cl +Cn1nccc1NC(=O)c1cc(Cl)ccc1F +CCC(C)NC(=O)Cn1nc(C)c2sc(C(C)C)nc2c1=O +O=C(NC1CCC(O)CC1)c1ccc2[nH]cnc2c1 +CCCN(CC(=O)OC)C(=O)c1ccc(C)nc1 +COc1ccc(CN(C(=O)COc2ccc(F)cc2)C2CC2)cc1 +O=C(Nc1cc(Cl)ccc1C(=O)N1CCCC1)c1ccc(F)cc1 +CC(NC(=O)CNCC(F)(F)F)c1cccc(N2CCCC2)c1 +CC(C)(C)CCC(=O)Nc1ccc(C(=O)N2CCOCC2)cc1 +COc1ccc2c(c1)cc(C(=O)NCCc1nc3ccccc3[nH]1)n2C +CCc1c(C)sc(NC(=O)COc2cc(C)ccc2C)c1C(N)=O +CC(C)NC(=O)C1CCN(C(=O)NC2CCCCC2)CC1 +COc1ccccc1CN(C(=O)Cc1c(C)nc(C)[nH]c1=O)C1CC1 +CNS(=O)(=O)C1CCN(C(=O)NCC(C)(C)c2ccncc2)C1 +COc1cc(C(=O)N2CCC(c3n[nH]c(C4CC4)n3)CC2)ccc1C +CSc1ccc(NC(=O)C2CC3CCC2O3)cc1 +N#Cc1nnn(CCCOc2ccccc2)c1-c1ccco1 +COc1ccc2c(c1)CCCN2C(=O)Cn1ncc2ccccc2c1=O +COCCNC(=O)C(C#N)Cc1ccc2c(c1)n(C)c(=O)n2C +NC(=O)C1CCN(C(=O)C2CCC(F)(F)CC2)c2ccccc21 +Cc1nc(C)n(-c2ccccc2NC(=O)N2CCC3(C2)OCCO3)n1 +CCOC(=O)c1cc(C(=O)NC(C)c2ccccc2)c(C)[nH]c1=O +COc1cc(C(=O)Nc2ccccc2F)ccc1OCC(N)=O +Cc1cc(C(=O)Nc2c(C)cc(Br)cc2C)ccc1N +CCCc1nc(C(=O)N2CCCC(O)(CO)C2)cs1 +COc1ccc(CCc2nc(C)c(CO)s2)c(OC)c1 +Cc1ccc(C(O)CNC(=O)Cc2cnc3ccccc3c2)cc1 +COCCn1cc(C(=O)N=c2sccn2C)c2ccccc21 +CC1Cc2ccccc2N1C(=O)NCCCN(C)S(C)(=O)=O +COc1cc(C)ccc1OC(=O)c1ccc(CN2CCCC2=O)cc1 +Cc1ccc2[nH]c3c(=O)n(CC(=O)Nc4ccccn4)ncc3c2c1 +Cc1nn(C)c(C)c1C1CCCN1Cc1nc(-c2ccoc2)no1 +COc1cc(C#N)ccc1C(N)C(=O)NCC(C)O +Cc1cc(=O)oc(C)c1C(=O)OCc1nc(C(C)C)no1 +COc1cccc(NC(=O)COC(=O)c2ccc3ncsc3c2)c1 +CC(CCc1ccccc1)NC(=O)Nc1cccnc1 +O=C(NCCc1ccccc1Cl)NCC1CC1 +COC(=O)c1cc(Cl)ccc1NC(=O)C1CCN(C(C)=O)CC1 +Cc1nc(CN2CC(C)OC(C)C2)nc2ccccc12 +COC(=O)c1cc(NC(=O)N(C)C(C)c2ccncc2)ccc1Cl +CC(C)NC(=O)CSc1nnnn1-c1cccc2ccccc12 +C=CCCCN(C)C(=O)Cc1csc(-c2nc[nH]n2)n1 +COc1cccc(NCC(O)COc2ccc(C)cc2)c1 +CCOCC(=O)N(C)Cc1cccnc1Oc1ccccc1 +COC(=O)c1ccccc1NCC(O)c1cccc(OC)c1 +CCOc1ccc(S(=O)(=O)NCc2nnc3ccccn23)cc1 +CCc1ccc(S(=O)(=O)NCc2cscn2)cc1 +NC(=O)c1cc(Cl)ccc1NCc1nnc(Cc2ccccc2)o1 +Cc1cc(=O)c(C(=O)Nc2cc(C(C)C)n[nH]2)nn1-c1ccccc1 +N#CCSc1nnc2c(=O)n(-c3ccc(F)c(F)c3)ccn12 +CC(C)N(C(=O)CCNC(=O)c1n[nH]c2ccccc12)C1CCC1 +Cc1cccc(C)c1NC(=O)CCCc1nc2ccccc2c(=O)[nH]1 +COCCN(Cc1scnc1C)CC(F)(F)F +Cc1cc(Cl)ccc1OCCN1CCC(=O)CC1 +Cc1cc(F)ccc1S(=O)(=O)NCc1nnc2ccccn12 +Cc1cc(C)c(NC(=O)CN2CCCn3nc(C)cc32)c(C)c1 +CCN(C)c1ccccc1NC(=O)Nc1ccccc1COC +Cc1cc(C)c2cc(C(=O)OCc3nnc(C)o3)[nH]c2c1 +O=c1[nH]nc2cc(-c3ccccc3)nc(-c3cccnc3)n12 +C#CCOc1ccc(C(=O)Nc2ccccc2)cc1 +COCC(=O)Nc1ccc(OC)c(-n2cnnn2)c1 +Cc1ccc(C)c(CC(=O)N2CCN(c3ccccc3C#N)C(=O)C2)c1 +Cc1[nH]c(C(=O)Nc2ccc3c(c2)OCO3)c(C)c1C(=O)OC(C)C +CC(C)Oc1ccc(NC(=O)NCC(=O)NC2CC2)cc1 +COc1ccc(OC)c(NC(=O)NC(C)CO)c1 +CCCN(CCc1ccccn1)C(=O)c1cnc(-c2ccco2)s1 +O=C(OCc1cccc(F)c1)c1cnc(C2CCCO2)s1 +O=C(Nc1cccnc1N1CCOCC1)c1cccc2c1OCCO2 +O=S1(=O)CCCN1CCN1CCCc2c(F)cccc21 +CN(C)C(=O)c1ccc(NC(=O)c2ccccc2)cc1 +Cc1cccc(NCc2nc(-c3ccccc3)no2)c1C(N)=O +CCC(O)c1c(C)nn(Cc2ccccc2Cl)c1C +O=C(COc1ccc2ccccc2c1Br)C1=NC=CC1 +CC(=O)c1ccc(NC(=O)C2CCN(S(C)(=O)=O)CC2)cc1 +O=C(Nc1ccnn1CC1CC1)c1nccn2ccnc12 +CNC(=O)N1CCC(n2c(=O)n(C)c3cncnc32)CC1 +Cc1nn(C(C)C)c2nc(C3CC3)cc(C(=O)Nc3cnn(C)c3)c12 +CC(C)Cc1nnc2n1NC(c1ccc(F)cc1)CS2 +O=C(Nc1ccccn1)c1ccc2nc(-n3cccc3)sc2c1 +CN(CCOc1ccccc1)C(=O)c1cc(C(N)=O)cs1 +N#CC(NC(=O)COCC1CC1)c1cccc(Cl)c1 +CC(C)N(C)C(=O)CSc1nnc2n1CCCCC2 +CCOC(=O)N1CCN(C(=O)CCCOc2ccccc2)CC1 +O=C(Nc1ccc(F)cc1)Nc1ccc(Cl)cn1 +Cc1ccc(S(N)(=O)=O)cc1C(=O)NCC1CCCCC1 +COc1ccc(C2CSc3nnc(C(C)(C)C)n3N2)cc1 +COc1c(C)cnc(CNC(=O)COc2ccc3c(c2)CCC3)c1C +CCC(C)CN(C)S(=O)(=O)c1cccc(C(C)O)c1 +O=C(OCc1ccccc1)C1CCCN1C(=O)c1cc(F)ccc1F +CCC(C)(C)NC(=O)COC(=O)c1cccc(NC(C)=O)c1 +Cn1ccc2cc(C(=O)NCCc3ccncc3)ccc21 +COc1ccc(-c2cc(C(=O)Nc3cccc(OC)c3)n[nH]2)cc1 +CN(C)c1ccc(C#CCNC(=O)c2cccc(F)c2)cc1 +CC(C)Oc1ccccc1NC(=O)C(C)Oc1ccccc1N +CCC(=O)N1CCc2cc(C(=O)NC3(C#N)CCCCC3)ccc21 +C=CCOc1ccc(-c2nc(-c3ccc(C#N)cn3)no2)cc1 +CCOc1ccc(Br)cc1S(=O)(=O)n1cnc(C)c1 +FC1(F)CCN(C2CCOCC2)CC12CCN(c1cccnc1)C2 +COC(=O)c1cnn(-c2nc3c(C)cccc3s2)c1N +Cc1occc1C(=O)NCc1ccnc(-n2ccnc2C)c1 +Cn1ccc(C(=O)N2CCC(c3nc(C4CCCC4)no3)C2)n1 +COc1ccc(C)nc1NC(=O)Cc1c(C)nn(C)c1C +Cc1ncc(CN(C)C(=O)c2n[nH]c(N)n2)s1 +NC(=O)CCCNC(=O)CNC(=O)c1ccc(Cl)cc1Cl +O=C(CCn1cnc2c([nH]c3ccccc32)c1=O)NC1CCCC1 +CCC(C)NC(=O)C(C)NC(=O)Cc1c(C)noc1C +Cc1ccc(NC(=O)C2CCN(S(C)(=O)=O)CC2)c(Cl)c1 +COc1cn(-c2ccccc2)nc1C(=O)NC1CCCCC1C +O=C(CNS(=O)(=O)c1ccccc1)N1CCc2ccccc2C1 +CC(=O)N1CCCC(c2nc(N(C)C)ncc2-c2cccc(F)c2)C1 +COc1ccc(C(=O)Nc2ccc(Cl)cn2)cc1Cl +CC(=O)Nc1ccc(C2Nc3ccccc3C(=O)N2C2CCCC2)cc1 +CC(CC(=O)NCC(=O)N1CCN(c2ccccc2)CC1)C1CC1 +COCCN(C)C(=O)Nc1cccc(Cl)c1N(C)C +COc1ccc(C(=O)N(Cc2ccccc2F)C2CC2)c(OC)c1 +CCC(CO)NC(=O)CCCc1ccc(Cl)cc1 +COc1ccc(NC(=O)c2cc(-n3cnnn3)ccc2Cl)cc1 +COc1ccccc1S(=O)(=O)N(CC(N)=O)C1CCCC1 +CC(=O)Nc1cc(C(=O)NCCc2ccc(F)cc2C)ccc1C +COc1ncccc1CNS(=O)(=O)N(C)C(C)C +CS(=O)(=O)Nc1ccc(NC(=O)CC2CCCC2)cc1 +Cc1n[nH]c(-c2ccc(C(=O)Nc3cccc(-c4ncon4)c3)cc2)n1 +C=CCc1cc(C(=O)Nc2nc(C)cs2)cc(OC)c1OC +CCc1nc2cc(C)cnc2n1Cc1ccccc1C#N +O=C(NCCN1CCN(C(=O)C2CCCCCC2)CC1)C1CCC1 +Cc1cnc(NC(=O)N2CCC(C(=O)Nc3ccccc3)CC2)s1 +Nc1cc(Cl)c(NC(=O)c2cccnc2)cc1Cl +COCCN1CCCCC1c1nc2ccccc2[nH]1 +CCCN(CC(=O)OCC)C(=O)c1cccc(N)c1 +c1ccc(CNc2nc3cc4c(cc3s2)OCCO4)cc1 +CC(C)c1nc2cc(N)ccc2n1CC(F)(F)F +CC1(C)CC(NC(=O)c2cccnc2C(F)(F)F)CCO1 +O=C(NCC1CCCCC1)C1CCCN(c2ncccn2)C1 +Cc1ccc(-c2nc(-c3ccccc3N)cs2)cn1 +N#CCOc1ccc(CC(=O)NCc2ccc(-n3cccn3)cc2)cc1 +CC(C)NC(=O)COC(=O)CCc1ccc(F)cc1 +COc1cc(C#N)ccc1Oc1ccc(F)cc1C(C)=O +CC(c1ccccc1Cl)N(C)C(=O)C1COc2ccccc2O1 +CCN1CC(C(=O)N2CC(Oc3ccc(F)cc3)C2)CC1=O +CCn1cc(C#N)c(=O)n(Cc2nc3ccccc3n2C(F)F)c1=O +O=C(CSc1nncs1)N1CCC(c2ccc(O)cc2)CC1 +COc1ccccc1NC(=O)c1cccc(S(=O)(=O)NC(C)C)c1 +CC(C)CNC(=O)c1snc(S(=O)(=O)C(C)C)c1N +CCNc1ncc(C(=O)Nc2ccc(O)c(C)c2)s1 +CCN(CC)C(=O)Nc1cc(NC(=O)C2CC2)ccc1C +Cc1noc(C2CCCN(C(C)c3nc(C4CC4)no3)C2)n1 +Cc1cccc(NC(=O)Cn2cnc3sccc3c2=O)c1 +CC(=O)c1cccc(NC(=O)NCc2ccc(CO)c(F)c2)c1 +COCCCNC(=O)c1nnc(Cc2ccccc2Cl)o1 +CCCN(CCC)C(=O)CC(C#N)c1ccccc1F +COc1cc(NC(=O)C(C)OCC(F)(F)F)ccc1NC(C)=O +Cc1cnc(-c2cccc(-c3ccn(CCCO)n3)c2)nc1N(C)C +CN(C)C(=O)c1c(NCc2ccncc2)ccn1C +Cc1cc(C)cc(NC(=O)C(C)Oc2ccc(S(C)(=O)=O)cc2)c1 +N#Cc1ccc(C(=O)NCC2CN3CCCCC3CO2)cc1 +Cc1ccc(C(=O)NCCNc2ncccn2)c(O)c1 +COc1ccc(NC(=O)Cc2ccc(F)cc2F)cn1 +Cn1ccnc1C1(O)CC2CCC(C1)N2C(=O)NCc1ccccc1 +COc1cccc(CCNC(=O)C2CC2(Cl)Cl)c1 +CC1(Cc2ccc3c(c2)OCO3)CCC(=O)N(Cc2ccncc2)C1 +CC(C)c1nnsc1CNC(=O)CC1NC(=O)c2ccccc21 +COC(=O)c1ccc(OC)c(Cn2cc(Br)cn2)c1 +O=C(NCCOc1cccc(F)c1)NC1CCCCC1 +COC(=O)Cc1ccc(OC(=O)Cc2c(C)noc2C)cc1 +Cn1nc(C(=O)N2CCCCC2c2cccnc2)ccc1=O +Cc1cccc(-c2nnc(SCC(=O)Nc3cc(C)on3)n2C)c1 +O=C(Cc1ccccc1Cl)NCc1cscn1 +O=C(NCCNc1cnccn1)c1cnn(-c2ccc(Cl)cc2)c1 +Cc1nc(COC(=O)Cc2ccc(F)cc2F)sc1C +CCOc1ccc(C(C)NS(=O)(=O)c2cnn(CC)c2C)cc1 +CCN(CCO)c1ncnc(Nc2ccc(Cl)cc2)c1N +CCCCNS(=O)(=O)c1ccc(OC)c(NC(C)=O)c1 +CC(C)(C)C(O)CN1CCN(C(=O)c2cccc(C(N)=O)c2)CC1 +CCC(=O)N1CCCC(C(=O)Nc2ccc(C)cc2C(=O)NC)C1 +CCC(C(=O)Nc1ccccc1)n1c(N)nnc1SC +CC(=O)N1CCN(C(=O)c2nccc3c(N)c(C)ccc23)CC1 +Cc1sc(=O)n(CC(=O)Oc2cccc(NC(=O)C3CC3)c2)c1C +COc1cccc(NC(=O)NCC(O)c2cccs2)c1OC +CCCOc1nc2c(c(=O)n(Cc3ccccc3)c(=O)n2C)n1C +Cc1ccc(NC(=O)CSc2nc(N)cc(N)n2)c(Cl)c1 +CCOc1ccc(C(=O)NCc2ccccc2-n2ccnc2C)cc1 +COc1cc(C)c(SCC(C)C(C)=O)cc1OC +C=CCN(Cc1cccs1)C(=O)C1CCC(=O)N1 +CC(Oc1ccccc1C(N)=O)C(=O)N1CCc2ccccc21 +O=C(Cn1ccccc1=O)Nc1cccc(OCCc2ccccc2)c1 +CN(C)c1nc(C(=O)c2ccc(Cl)cc2)cs1 +O=C(COc1ccc(F)cc1)Nc1cccc(F)c1 +Cc1oc(-c2ccsc2)nc1CSc1nnc(N)n1C1CC1 +O=C(Cn1cnnn1)N1CCN(C(=O)c2ccc3c(c2)CCC3)CC1 +O=C(Cn1ccc(C(F)(F)F)n1)Nc1ccc(N2CCCC2)cn1 +Cc1cc(C)c(C(=O)OC(C)C(=O)NCC(F)(F)F)c(C)c1 +O=C(Nc1nc2cc(F)c(F)cc2s1)c1cn2cccnc2n1 +COc1ccnc(N2CCN(C(=O)c3ccc(O)c(Cl)c3)CC2)n1 +O=C(Cc1cccc(F)c1)N1CCC2(CC1)Cc1ccccc1C2=O +O=C(CC(F)(F)F)N(Cc1ccccc1)CC1CCC1 +COc1ccc(C)cc1C(C)NC(C)C(=O)NC1CC1 +COCC(=O)N1CCC(c2ccc(C(=O)OC)cc2)CC1 +Cc1nnc(SCC(O)c2ccccc2Cl)n1C1CC1 +O=C(NCc1nc(C2CC2)no1)NCC1(c2ccc(Cl)cc2)CC1 +O=C(Nc1nncs1)N1CCC(CCc2ccc(O)cc2)CC1 +Cc1cc(Br)ccc1OC(=O)c1cc(C(N)=O)c[nH]1 +CC1(C)C(NC(=O)N2CCCCCC2)C2CCOC21 +CC(=O)NCCCCCC(=O)Nc1ccccc1Cl +CCCc1nc(C(=O)N(C)C(C)c2cncs2)cs1 +C#CCOC(=O)C1CCCN1S(=O)(=O)c1ccc(C)s1 +Cn1cc(CNC(=O)c2[nH]c3ccccc3c2Br)cn1 +Cc1cc(C)nc(C(C#N)C(=O)Cc2ccccc2C)n1 +O=C(NCc1ccncc1)Nc1cccc(OCC(F)F)n1 +O=C(NCc1ccc(F)cc1)NCc1ccccc1Cn1cccn1 +OCCCN(Cc1ccc(F)c(F)c1)c1ccccc1 +Cc1n[nH]cc1CNC(=O)c1ccnc(N(C)C)c1 +CCn1c(C)cc(C(=O)CN(CCO)c2ccccc2)c1C +C=CCn1c(N2CCN(CC(N)=O)CC2)nc2c1c(=O)[nH]c(=O)n2C +C#CCCNS(=O)(=O)c1ccc(OCC)cc1 +COc1ccc(C)cc1-c1csc(CN2CCN(C(C)=O)CC2)n1 +O=C1CCC(NC(=O)CCc2ccccc2O)CN1 +CC(=O)Nc1cccc(C(=O)OCc2ccccc2F)c1 +O=C1COc2ccc(NC(=O)c3cc(Br)c[nH]3)cc2N1 +c1ccc(-n2cccn2)c(CN2CCOC3(CCC3)C2)c1 +CCc1nc(CC(=O)Oc2cccc(C(C)=O)c2)cs1 +CS(=O)(=O)NC1CCCN(C(=O)C2COc3ccccc3O2)C1 +NC(=O)NCCCCC(=O)Nc1ccc(F)c(F)c1 +Cc1cccc(NC(=O)Cn2c(C)nc3ccccc3c2=O)c1 +O=C(COCC1CCCO1)Nc1nc(C2CC2)cs1 +COc1ccc(-n2nnc(C(=O)Nc3ccon3)n2)cc1 +Cc1cc(C(=O)N2CCOCC2c2csc(C)n2)c(C)o1 +COc1cc(OC)cc(-c2nc3ccccc3n2CCCC#N)c1 +Cc1occc1C(=O)NCCCNc1cccnc1 +O=C(NCc1ccc(-n2cccn2)cc1)c1cccc(-c2ccoc2)c1 +COC(=O)Cn1c(-c2ccccc2)nc2cccnc21 +COc1cc(SC)ccc1C(=O)NC1CCC(O)CC1 +Cc1cc(C)c(NC(=O)C(C)Sc2nc(N)cc(N)n2)c(C)c1 +CCS(=O)(=O)c1noc(C(=O)NCC(C)C)c1N +O=C(c1ccccc1F)N1CCN(C(=O)N2CCOCC2)CC1 +Cc1nn(CCC(=O)Nc2ccccc2)c(=O)c2noc(C)c12 +CCOc1ccc(-c2csc(NC(=O)c3ccnn3CC)n2)cc1 +O=C(NCCNc1ncccn1)N1CCCC(C(F)(F)F)C1 +c1cc(OCc2cscn2)cc(-c2nc(-c3ccncc3)no2)c1 +Cc1ccc(-c2nn(CC(N)=O)c(=O)c3nc(C)sc23)cc1 +CC(C)OC(=O)C1CCCN1Cc1cc(C(N)=O)cs1 +O=C(NCCNC(=O)C1CCCN1C(=O)C1CC1)c1ccccc1 +CCCCCC1CC(CC#CCN2CCOCC2)C(=O)O1 +CCOC(=O)c1cc(C(C)(C)C)n(C2CCN(C(=O)CC)CC2)n1 +CCOc1cccc(CNC(c2ccccc2)c2n[nH]c(C)n2)c1 +COc1ccc(-c2nc(C#N)c(NCCCn3ccnc3)o2)cc1 +CCCN(CC)S(=O)(=O)c1ccc(C)cc1N +CC1CN(Cc2ccccc2NC(=O)N2CCCC2)CC(C)O1 +CC(=O)N1CCc2cc(NC(=O)NCC3CCCC(C)C3)ccc21 +CCC1CCCCN1C(=O)c1onc(-c2cccnc2)c1N +Cc1cc(C)c2cc(C(=O)N3CCNC(=O)C3)[nH]c2c1C +CCCn1c(SCC(N)=O)nnc1-c1csc(C)c1 +Cc1noc(C)c1CNC(=O)NCC(CO)Cc1ccccc1 +CCC(C)(C)NS(=O)(=O)c1cccc(Cl)c1 +CC(C)c1nc(N2CCC3(CCO3)CC2)c2cnn(C)c2n1 +CC1(C)C2CC=C(CCOC(=O)C3CCCN(C(N)=O)C3)C1C2 +O=S(=O)(NC1CCc2cc(F)ccc21)N1CCCCC1 +CCCn1cc(-c2ccnc(NC3CCC(O)CC3)n2)c(C)n1 +O=C(c1cncnc1)c1ccc(Br)cc1F +CCSc1cc(C(=O)NCCn2nc3ccccn3c2=O)ccn1 +CC(OCC1CC1)C(=O)Nc1ccccc1C(N)=O +c1cncc(CC2C(N3CCOCC3)CCN2Cc2nccs2)c1 +C=CCn1ccc2c(OCC(=O)NCc3ccccc3)cccc2c1=O +O=C1CCC2(CCCO2)CCN1Cc1ccccc1C(F)(F)F +O=C(NCc1ccccc1F)c1cc(-c2ccco2)no1 +COc1ccnc(NCCNC(=O)c2ccc(C(F)(F)F)cc2)n1 +COc1ccc(C(=O)OCc2nc(-c3cccc(Cl)c3)no2)cn1 +Cc1cccc(CNC(=O)Cn2c(C)c(C)sc2=O)n1 +Cc1cc(C)cc(-n2ccnc2SCC(=O)NCCCO)c1 +COc1cccc(-c2nnc(NC(=O)C(C)(C)C)s2)c1 +COC(=O)c1cccc(NC(=O)CC2CCCC2)c1 +COc1cccc2cc(C(=O)N3CCCC3c3ccc[nH]3)oc12 +Nc1c(NCc2ccc(F)cc2)ncnc1N1CCN(CCO)CC1 +CN(C)c1nc(CNc2ccc(CC(F)(F)F)cc2)ns1 +Cc1cnc(C(=O)Nc2nnc(SCc3ccccc3)s2)cn1 +CCNC(=O)CNc1nc2sc3c(c2c(=O)n1C)CCCC3 +COc1ccc(OC(C)C(=O)Oc2ccc(C(C)=O)cc2)cc1 +Cn1nc(CNS(=O)(=O)Cc2ccccc2)cc1-c1ccncc1 +CC(C)(C)OC(=O)N1CCC(COc2ncccc2O)C1 +COc1cc(C#N)ccc1OCC(=O)N1CCOC2CCCCC21 +CCC1CCCN(C(=O)c2cccnc2-n2cccn2)C1 +Cc1ccc(C)c(OC(=O)CCc2c(C)nc3ncnn3c2C)c1 +CN(CCOc1ccccc1)C(=O)c1nccnc1N +CNc1ccccc1C(=O)N(C)CCC(=O)OC +COc1cccc(OC(=O)Cn2c(C)c(C)sc2=O)c1 +CCOc1ccc(-c2cn3cc(C)cc(N)c3n2)cc1 +Cc1cnc(C(=O)Nc2ccc3c(c2)nc2n3CCCCC2)cn1 +O=C(CSc1ncc2ccccn12)NCC1CCCO1 +Cc1cc(NC(=O)CCn2nc(C)c(Br)c2C)no1 +CC(C)(O)Cn1cnc2c(N3CCOCC3)ncnc21 +Cn1ccnc1SCCNCc1cc(=O)c2ccccc2[nH]1 +COCCNC(=O)N1CC(c2nc3ccccc3[nH]2)C1 +COc1ccc(S(=O)(=O)N(C)CCOc2ccc(F)cc2)cc1 +Cc1ccc(CNC(=O)CSc2ncccc2C#N)cc1C +CCCCC(=O)N1CC(OCc2cccc(F)c2)C1 +CCCS(=O)(=O)NC(C)c1ccc2c(c1)OCCO2 +CC(C)c1nnc2n1CCN(C(=O)CN1Cc3ccccc3C1=O)C2 +CC(C)N(C)C(=O)C1CCCC(C(F)(F)F)C1 +Cc1cc(C)n(CCC(=O)NCc2ccc(F)cc2)n1 +Cc1nc(CN2CCC(OCC3CC3)C2Cc2cccnc2)cs1 +CCc1nnc(NC(=O)NCc2cnc(C)s2)s1 +COCCNc1ncnc(Nc2ccc(OC)cc2)c1N +CC(NC(=O)CCCc1ccccn1)c1ccccc1-n1cccn1 +C#CCNC(=O)CCc1nc(-c2cc(Cl)c(OC)c(OC)c2)no1 +CC(C)(C)CC(=O)Nc1cccc(NS(C)(=O)=O)c1 +COCC(=O)N1CCC2(CC1)NC(=O)c1ccccc1O2 +OC1CCN(c2ncnc3cc(F)c(F)cc23)C1 +Cn1ncc2cc(C(=O)Nc3ccc(F)cc3F)c(N)nc21 +COC(=O)CN(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1 +CN(C)C(=O)C1CCN(C(=O)C2CC(=O)N(c3ccccc3)C2)CC1 +COc1ccc(OC)c(C(=O)Nc2cc(C)nn2-c2ccccc2)c1 +Cn1ncc(Cl)c1C(=O)N1CCCC1c1ccc(F)cc1 +CCNS(=O)(=O)c1cccc(C(=O)NC2CCCC(C)C2C)c1 +CNC(=O)CC1CC2CN(S(=O)(=O)c3ccc(C)cc3)CC2O1 +CCC(C)NC(=O)NCc1ccc(S(N)(=O)=O)s1 +Cc1ccnc(C(Nc2nc3c(s2)c(C)nn3C)C2CC2)c1 +CN(Cc1cccs1)C(=O)C1Cc2cc(Cl)ccc2O1 +N#Cc1ccc(NC2CCN(C(=O)c3ccoc3)CC2)c(F)c1 +CCC(C)(C)NC(=O)Cn1c(-c2cccc(F)c2)csc1=O +CCOc1cc(CNC(=O)Cc2cn3ccsc3n2)ccc1OC +CN(Cc1ccncc1)C(=O)NCc1cc2ccccc2o1 +COC(=O)c1ccc(Cc2nc3scc(C(C)C)c3c(=O)[nH]2)o1 +CC(C)(C)C(=O)NCC(=O)NCc1ccccc1Cn1cccn1 +O=C(Nc1cccc(-c2nnco2)c1)c1ccc(Cl)cc1F +Cc1cccc(CCCOC(=O)Cc2c(F)cccc2F)n1 +C=CCn1c(SCc2n[nH]c(=O)[nH]2)nnc1-c1ccccc1OC +CCN1CCN(C(=O)C2CCN(c3nccc(C)n3)CC2)CC1 +CC(C)C(=O)N1CCCC1C(=O)OCc1cccc(C(N)=O)c1 +Cc1cc(C(=O)NC(C)C(=O)NCc2ccccc2)c(C)n1C1CC1 +Cc1ccc(NC(=O)Cn2c(C)nc3onc(C)c3c2=O)cc1F +COc1ccc(-c2c(C#N)nnn2-c2ccccc2F)cc1 +COc1ccc(OCCc2nnc(-c3ccccc3)o2)cc1 +CCCn1c(N)c(C(=O)CN2CCC(O)CC2)c(=O)[nH]c1=O +Cc1c(C)n2c3c(=O)n(C)c(=O)n(C)c3nc2n1C +COc1ccc(C(=O)C(C)C)cc1S(=O)(=O)N(C)C +CC(C)(C(N)=O)N1CCN(C(=O)NCc2ccc3c(c2)OCO3)CC1 +N#Cc1c(F)cccc1SCCCNc1ncccn1 +CCN(Cc1ccoc1)C(=O)NC(c1ccccc1)c1nccn1C +O=C(NC1CC(=O)N(c2cccc(F)c2)C1)c1ccc2ccccc2c1 +CCS(=O)(=O)NC1CCN(C(=O)CC(C)(C)C)CC1 +N#CCCCn1c(-c2cccnc2)nc2cc3c(cc21)OCCO3 +CC1(C)CN(Cc2nc(-c3cccs3)no2)CCO1 +O=C(Cc1nc2ccccc2c(=O)[nH]1)Nc1ccccc1Cl +O=C(Nc1nnc(-c2ccncc2)o1)c1cc(=O)c2ccccc2o1 +COc1cc(CSc2nnc(N)n2C(C)C)ccc1SC +CC(C)CNC(=O)c1ccc(NC(=O)c2ccoc2)cc1Cl +Cc1ccc(C(O)CNC(=O)CSc2ccc(F)cc2)o1 +COc1ccccc1-c1noc(COc2cccc(C(N)=O)c2)n1 +Cc1cccc(N2CCN(CCNC(=O)C3CCCO3)CC2)c1 +CC(C)CC(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O +CCNC(=O)c1ccc(NC(=O)CCNC(=O)c2ccco2)c(C)c1 +Cc1noc(-c2ccc(C(=O)Nc3ccccc3C(F)(F)F)cc2)n1 +Cc1nn(CC(=O)NCc2cscn2)c(=O)c2ccccc12 +CCCc1nnc(NC(=O)C2COc3ccccc3O2)s1 +CC(C)NC(=O)Nc1ccccc1C(=O)N1CCOC2CCCCC21 +O=C(CCc1ccsc1)NCc1nc2ccccc2[nH]1 +Cc1nn(CCC#N)c(C)c1CCC(=O)N1CC(C)OC(C)C1 +COc1ccc(-c2cc(C(=O)N3CCCCCC3)n[nH]2)cc1 +Cc1noc(-c2cccc(NC(=O)c3ccccc3C)c2)n1 +CCC(=O)Nc1cc2nn(-c3ccccc3)nc2cc1Cl +CCc1ncc(C(=O)NC(CC(C)C)C(=O)N(C)C)s1 +Cc1cc(C)cc(NCc2c[nH]nc2-c2ccc(C)o2)c1 +CNC(=O)c1ccc(COc2cccc(F)c2C#N)cc1 +COc1cccc(C(=O)COc2ncnc3ccccc23)c1 +O=C(NCC(F)(F)F)N(CCCO)C1CCc2ccccc21 +Cc1cc(C(=O)Nc2nc3ccccc3[nH]2)c2ccc(F)cc2n1 +COc1cccc(Nc2nnc(SCCCC#N)s2)c1 +COc1ccc(C(=O)NCCN2CCOCC2)c(N)c1 +CCc1ccccc1NC(=O)c1ccc(CN2CCOCC2)cc1 +CCC(NC(=O)NC1(C)Cc2ccccc2C1)c1ccncc1 +Cc1nnc(SCc2c(C(=O)N(C)C)oc3ccccc23)s1 +CSc1ncc(C(=O)Nc2ccccc2)n1-c1ccc(F)cc1 +CC(C)CCNC(=O)NCc1ccc(Cn2ccnc2)cc1 +C#CCNC(=O)c1ccccc1NC(=O)Cn1nc2ccccn2c1=O +CCC(C)Nc1nc(-c2cccn(CC)c2=O)cs1 +N#CC(C(=O)c1cc(C(N)=O)cs1)c1ccccn1 +CCc1nc(NC(=O)Cc2c(C)noc2C)sc1C +CCNC(=O)CNC(=O)c1cc(Cl)ccc1OC(C)C +C=CCNc1ncnc(Oc2ccc(OC)cc2)c1N +Cc1ccccc1C(C)NS(=O)(=O)c1cccc(F)c1 +CC(=O)c1ccc(NC(=O)NC(C)C2CCC2)cc1C +COC(=O)c1ccc2nc(-c3c(F)cccc3Cl)nn2c1 +C#CCN1C(=O)C(C)(C)Oc2c(OC)cc(CO)cc21 +Cc1cc(NC(=O)c2ccc(Br)cn2)c2ncccc2c1 +O=S(=O)(Cc1ccccc1)N(CCc1cccs1)C1CC1 +Cc1nsc(N2CCN(C(=O)c3c[nH]c4cccc(F)c34)CC2)n1 +O=C1CN(C(=O)Nc2ccc3c(c2)COC3)C2CCCCC2N1 +CC1(C)CN(CCNC(=O)Nc2cccnc2)CCO1 +Cc1cccnc1CNC(=O)c1ccccc1Br +CC(CCC1CCCO1)NC(=O)c1ccccc1Br +CSc1nc(NC(C)C)c2cnn(CCNC(=O)C(C)C)c2n1 +Cc1nc(-c2cccnc2)sc1C(=O)NCC(C)C +CC(C)(C)OC(=O)N1CCC(CNc2cnccn2)CC1 +NC(=O)Cn1cnc2ccc(Br)cc2c1=O +CCC(=O)N1CCc2cc(C(=O)NCCCC(N)=O)ccc21 +CCCN(CCC)S(=O)(=O)c1ccnc(N)c1 +CC1CN(CCC(O)c2ccccc2Cl)CC(C)O1 +CC(=O)N(C)Cc1ccccc1NCc1cnc2nc(C)cc(C)n12 +O=S(=O)(c1cccnc1)N1CCC2(CCc3ccccc3O2)CC1 +Cc1ccc(CN(C(=O)C2CCC(=O)N2)C2CC2)cc1C +NC(=O)c1cccc(CN2CCc3cncnc3C2)c1 +Cc1c(C(=O)N2C(C)CC3CCCCC32)cnn1-c1ccncc1 +CC(=O)c1c(C)[nH]c(C(=O)NC(c2nc(C3CC3)no2)C(C)C)c1C +O=c1[nH]c(CNc2cccc(F)c2)nn1Cc1ccccc1F +Cc1cc(C)n(-c2nc(C)nc3c2cnn3-c2ccccc2)n1 +COC(=O)C(Cc1ccc(F)cc1)NC(=O)c1ccncc1Cl +O=S(=O)(Cc1ccccc1)N1CCN(c2cccc(F)n2)CC1 +Cc1cc(C)c(C(=O)Nc2cccc(COCC3CC3)c2)c(=O)[nH]1 +COc1ccccc1C(=O)OCC(=O)Nc1cccc(F)c1 +O=C(Nc1ccccn1)C1CCN(C(=O)NCC2CCCO2)CC1 +CS(=O)(=O)NCc1ccc(-c2nc(-c3ccsc3)no2)o1 +Cc1ccc(S(=O)(=O)N2CC(CO)OCC2C)c2cccnc12 +COc1cc(OC)c(C(=O)NCCCO)c(OC)c1 +N#Cc1c(-c2cccnc2)cc2c(c1N)c(=O)oc1ccccc12 +CCCCc1nnc(SCC(=O)Nc2ccccc2)n1N +Cc1c(C(=O)NCC2CCC(C)(C)CC2)cccc1N1CCNC1=O +COC(=O)NCC(=O)NC(C)C(=O)NC(C)(C)C +CNc1ncc(S(=O)(=O)NCC(=O)NC(C)C)cn1 +CCOC(=O)C1C(=O)C(C(=O)OCC)C(C)N(C)C1C +COc1ccc(C(=O)NC2COC3C(O)COC23)cc1 +O=C(NCCN1CCOCC1)C1CCC(=O)N1C1CCCCC1 +CC(C)COc1cncc(N2CCN(C3CC3)C(=O)C2)n1 +Cc1nn(C)c2cnn(CCCNC(=O)c3cccnc3)c12 +CCCN(C)C(=O)Nc1ccccc1N1CCCC1 +CC1(NC(=O)COCC(F)(F)F)Cc2ccccc2C1 +O=C1CC(C(=O)NCC2CCCCC2)c2ccccc2N1 +Cc1nn(C)c(C)c1NC(=O)c1nn(C)c(C)c1Br +COc1nc2ccccc2cc1CNc1cccc(N2CCNC2=O)c1 +O=C(CCCn1nc(-c2ccco2)ccc1=O)Nc1nccs1 +Cc1onc(-c2ccccc2)c1C(=O)NCc1ncn(C)n1 +CCC(C)n1ncc(C(=O)N2CCc3sccc3C2)c1C1CC1 +Cn1cnn(CC(=O)N2CCc3ccccc3C2)c1=O +CCS(=O)(=O)N1CC2CCC1CN(C(=O)c1ccncc1)C2 +CCn1cc(C(=O)N(C)CCOc2cc(C)cc(C)c2)cn1 +Cc1cc(F)ccc1S(=O)(=O)NCC1(O)CCc2ccccc2C1 +NC(=O)C1CCN(C(=O)NCc2cnn(-c3ccccc3)c2)CC1 +CCNS(=O)(=O)c1ccc(NC(=O)C(C)Oc2ccccc2)cc1 +Cc1ocnc1CNC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C1Nc2cc(F)ccc2C1NCCc1ccccn1 +Cc1ccc2nc(COCC(=O)NCCCO)[nH]c2c1 +C=CCN1C(=O)CCCC12CCCN(C(=O)Nc1ccc(C)cc1)C2 +Cc1ccn(CCNC(=O)c2ccc(-c3ccccc3Cl)o2)n1 +Cc1ccc(NC(=O)CN2CCOCC2C2CC2)cc1 +Cn1nnc2cc(NC(=O)Nc3cccc(F)c3)ccc21 +O=C(Cn1nnc(-c2ccccc2)n1)NCc1ccc(Cl)cc1 +CC(C)N(C)C(=O)NC1CCN(S(=O)(=O)c2cnn(C)c2)CC1 +CC(NC(=O)CNc1ccc(-n2nccn2)cc1)c1ccc(F)cc1 +Cc1ccc(N2CCCC2)c(C(=O)NCCNC(=O)OC(C)(C)C)c1 +O=C(CC1CCOCC1)Nc1ccc(Cl)cc1 +O=C(CSc1ccc(-n2ccnc2)nn1)NC1CCCCC1 +CC(C)c1noc(C(C)N2CCN(Cc3cscn3)CC2)n1 +CC(=O)NC1CCN(C(=O)c2ccnc(OC3CCC3)c2)CC1 +Cc1cccc(CCC(=O)NCCNC(=O)c2ccc(F)cc2)c1 +CN(CCC(F)(F)F)C(=O)CCc1ccccc1O +COc1cc(Br)c(C(=O)C2COCCO2)cc1OC +O=C1Cc2ccccc2N1CCOc1cccc2cccnc12 +O=C(NCc1ccc(Oc2ccc(F)cc2)cc1)C1CCOCC1 +Cc1cc(C(=O)NCC(=O)NCc2cccnc2)nn1C +O=C(CCn1ccccc1=O)NC1CCOc2c(Cl)cccc21 +CC(=O)N1CCc2cc(NC(=O)c3cnccn3)ccc21 +Cc1cc(F)ccc1NCC(=O)N1CCOCC1 +NC(=O)C(Cc1ccccc1)NC(=O)c1ccc(Cl)cc1Cl +Cn1nnc2cc(C(=O)N3CCCC(Nc4ccccc4)C3)cnc21 +COc1ccc(-c2nc3cnccc3o2)cc1NC(=O)CC(C)C +COC(=O)c1ccc(CN(C)C(=O)C(C)(C)C)cc1 +CCCOc1ccc(-c2nc(C3CCOC3)no2)cc1Cl +O=C(COc1ccccc1)NCC(=O)N1CCOCC1 +Cc1c(C(=O)N(C)C(C)c2ccncc2)cnn1C +CNS(=O)(=O)Cc1ccc(CNc2ncccc2C#N)cc1 +CN(Cc1ccccc1)c1ncnc(Nc2ccccc2)c1N +COc1ccccc1S(=O)(=O)N=c1[nH]cccc1C +Cc1ccc(C(N)=O)cc1NC(=O)NCCCO +Clc1ccc2c(c1)CN(Cc1nnc(C3CCC3)o1)CC2 +NC(=O)C1(CNC(=O)Cc2ccc(Cl)cc2Cl)CCCC1 +O=S(=O)(NCc1ccc(F)cc1)c1ccc(Cl)cc1F +CC(C)c1ncc(Cl)c(C(=O)N(C)c2cccc(F)c2)n1 +Cc1ccc(OC(=O)Cc2cc3ccccc3[nH]c2=O)cc1C +CCn1cc(CNc2nncc(-c3ccc(F)cc3)n2)cn1 +COc1cc(NC2CCCN(C(=O)C(C)(C)C#N)C2)cc(OC)c1 +C#CCN1CCN(C(=O)NCc2ccc(O)c(F)c2)CC1 +Cc1ccsc1C(O)CNC(=O)Nc1cccs1 +Cc1cnc(C(C)(C)NC(=O)NCc2nc(-c3ccco3)n[nH]2)s1 +COc1cc(C(=O)NCC2CC2C)cc(OC)c1OC +CC(C)(C)OC(=O)CN1CCN(c2ncnc3sccc23)CC1 +Cc1cccc(CNC(=O)CCc2cccc(N)c2)c1 +CCn1cc(C(=O)Nc2cc(F)c(OC)cc2OC)cn1 +Nc1cc(-c2nc(-c3ccccn3)cs2)ccc1Cl +CCN1CCN(C(=O)C2CN(S(=O)(=O)C3CC3)C2)CC1 +Nc1cc2c(cc1Oc1ccc(F)cc1F)OCCO2 +Cc1n[nH]c(C)c1NC(=O)CSc1ccccc1Br +CNS(=O)(=O)NC(Cc1ccccc1)C(=O)OC +O=C1Nc2cc(F)ccc2C1Nc1ccc(F)cc1F +COCCn1cc(NC2CC3CC=CC32)ccc1=O +CCC(C)N(Cc1ccccc1)C(=O)C1CCN(C(=O)C2CC2)CC1 +CC1=C(C(=O)OC(C)C)C(C)N=C1C(=O)NCc1nc(C)cs1 +CC(C)C(=O)Nc1cccc(NC(=O)NCCc2ccncc2)c1 +O=C(CC1COCCN1Cc1noc(C2CC2)n1)c1ccccc1 +N#CCCN(CCC#N)C(=O)COc1ccc(Cl)cc1Cl +Cc1cc(NC(=O)COc2cccc(-n3cncn3)c2)n(C)n1 +COc1ccc(C(=O)c2ccc(OC(F)F)c(N)c2)cc1OC +COc1ccnc(NC(=O)C2(c3cccc(Cl)c3)CC2)c1 +COc1ccc(CCC(=O)NCc2ccc(Cl)cc2)cc1N +CCOC(=O)c1c(C)n[nH]c1NCc1ccccc1 +COC(=O)c1ccccc1NC(=O)C(C)c1cccs1 +Cc1ccc(NC(=O)CCNS(C)(=O)=O)c(O)c1 +Nc1[nH]nc(-c2ccco2)c1-c1ccccc1Cl +OCc1cc(F)cc(CO)c1OCc1cnn(-c2ccccc2)n1 +Cc1cc(C)n2nc(C(=O)N(C3CC3)C(C)C3CC3)nc2n1 +CC1CN(C(=O)OC(C)(C)C)CCN1C(C)c1nccs1 +CC(NC(=O)COc1ccc(F)cc1)c1ccncc1 +COc1ccc(CNc2cnn(CC(N)=O)c2)cc1 +Nc1cccc(CNc2ccccc2S(N)(=O)=O)c1 +CC(=O)c1cccc(NC(=O)c2cc(C3CC3)nc3c2c(C)nn3C)c1 +CN(C)c1ncccc1C(=O)N1CCC(C(=O)c2ccccc2)CC1 +CCN(C)C(=O)c1csc(NC(=O)c2ccc(F)c(F)c2)n1 +CC(C)(C)c1nc(Cn2nc(-c3ccco3)oc2=O)cs1 +CC(Cc1ccccc1F)Nc1ccc(C#N)cn1 +O=C(NCCc1nnc2ccccn12)c1cc2ccccc2oc1=O +CCC(CC)C(=O)Nc1nc2cc3c(cc2s1)OCCO3 +Cc1nn(CCC(=O)NCc2ccco2)c(C)c1Cl +CCOCCNC(=O)N(C)CCc1ccccc1 +O=C(NC1CCCN(c2ncccn2)C1)NC1CCCCNC1=O +CC(Oc1ccccc1F)c1nnc(SCC#N)o1 +Cc1cccc(CNC(=O)NC2CCOc3c(Cl)cccc32)n1 +CN1C(=O)CC(C(=O)NCc2ccco2)C1c1ccc(F)cc1 +O=C(NC1C2CC3CC(C2)CC1C3)c1ccsc1 +Oc1ccc2c(c1)C1CCCC1(N1CCOCC1)O2 +COc1cc(CNC(=O)NC(C)c2ccc(F)c(F)c2)ccn1 +CC1(C)COCCN1c1cc(Cl)ccc1C#N +CC1CC1CNC(=O)c1ccnc(-n2ccnc2)c1 +COc1cc(C)c(C(=O)NC2CCCC(C)C2)cc1OC +N#CCCN(Cc1cccc(C#N)c1)c1ccccc1 +N#Cc1cc(F)ccc1NCC1CN2CCCCC2CO1 +COc1ccccc1C(C)NC(=O)N1CCCC(C(=O)NC2CC2)C1 +O=C(NC1CC1)c1ccc(NCc2nc(-c3ccccc3)no2)cc1 +CC(=O)Oc1cc(C)cc2oc(=O)c3c(c12)CCCC3 +CCOCCCNC(=O)c1cnc2cc(C(=O)N(C)C)n(C)c2c1 +O=C(CCc1cc(Cl)cs1)NCc1ccccn1 +Nc1ccc(S(=O)(=O)N2CCCc3ccccc32)cn1 +Cn1nc2n(c1=O)CCN(CC(=O)NC1CCCCC1)C2 +C=C(C)CSc1ncc(C(=O)OCC)c(N)n1 +CN(CC(=O)NCc1cnn(-c2ccccc2)c1)C(=O)c1ccccc1 +COCCN1CC(C(=O)NCc2ccc(-n3cncn3)cc2)CC1=O +COC(=O)c1cc2cc(OC)cc(Br)c2o1 +N#Cc1ccc(Oc2cccc(NC(=O)NCCn3cccc3)c2)nc1 +CC(C)(C)OC(=O)N1CCC2(CCCC2CO)CC1 +Cn1ncc(Cl)c1C1CCCCCN1C(=O)c1cc(C2CC2)on1 +Nc1nc(SCc2nnc(-c3cccs3)o2)n[nH]1 +CCOC(=O)c1nn(-c2ccccc2C(F)(F)F)c(N)c1C#N +CC(=O)c1ccc(NC(=O)C(C)OC(=O)c2ccc(F)cc2N)cc1 +CCC(=O)Nc1ccc(N2CC(C(=O)OC)CC2=O)cc1 +CCOCC(=O)Nc1cc(-c2n[nH]c(=O)[nH]2)cc(C(F)(F)F)c1 +N#Cc1ccc(OCC(=O)N2CCCC2c2noc(C3CC3)n2)cc1 +O=C(Nc1ccc(Br)cc1)NC1C2CCC(C2)C1CO +Cn1nc2n(c1=O)CCN(C(C(N)=O)c1ccccc1)C2 +Cc1sc(=O)n(CC(=O)Nc2cccc3ccccc23)c1C +CCOc1ccc(CNS(=O)(=O)c2ccc(OC)c(F)c2)cc1 +CN(C)C(=O)CN(C)C(=O)c1ccc(COc2ccc(C#N)cc2)o1 +O=C(c1ccoc1)N(c1ccc(O)cc1)S(=O)(=O)c1ccccc1 +Cc1cc(CN2CCCC(c3cc(C(F)(F)F)[nH]n3)C2)no1 +CCN(Cc1ccccc1C)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +Cc1ccccc1NC(=O)c1ccc(-c2ccccn2)nc1N +CCn1cc(CNC(=O)c2cc3ncc(Br)cn3n2)cn1 +COc1ccccc1NCC(=O)NC(C)(C#N)C(C)C +CC1CC=CCC1COC(=O)CCNC(=O)c1ccco1 +Cc1ccc(NC(=O)C2CCCN(C(=O)C3CC3)C2)nc1 +O=C(c1nnc2ccc(N3CCOCC3)cc2n1)N1CCCC1 +CCC(CC)NS(=O)(=O)c1ccc2c(c1)OCCO2 +CN(C(=O)c1cc(F)c(F)c(F)c1F)c1ncccc1C#N +Cc1cnc(NC(=O)C(C)Oc2ccc3c(c2)CCC3)s1 +CC(C)(C)C(=O)N1Cc2ccc(C(O)C3CCCO3)cc2C1 +COc1cccc(NC(=O)C(O)c2ccc(C)cc2)c1 +CCOc1ccccc1-c1nnc(SCC(=O)NC2CCCC2)o1 +COc1ccc(NC(=O)Nc2ccon2)cc1OC +Nc1ccccc1N1CCN(C(=O)c2ccccc2F)CC1 +Cc1cccc(OC2CCN(C(=O)NCc3ccccc3)CC2)n1 +C=CCNC(=O)C(C)N(CC)Cc1nc2ccccc2c(=O)[nH]1 +O=C(NCCCN1CCCC1=O)c1ccc2c(c1)OCO2 +CC(=O)N1CCN(S(=O)(=O)N2CC(C)OC(C)C2)CC1 +COc1ccc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)cc1 +O=S(=O)(Nc1ccc(F)c(Cl)c1)c1ccc2c(c1)OCCO2 +CC(C)c1noc(CCC(=O)N2CCN(c3ccccc3O)CC2)n1 +CCN(CC)S(=O)(=O)N(CC(N)=O)C1CCCC1 +CCOC1CCC2C1OCCN2CCc1ccc(OC)c(OC)c1 +CCc1cc(NC(=O)c2cccc(C#N)c2)nn1-c1ccc(C#N)cc1 +Cc1n[nH]c(C2CN(CC(=O)N3CCCc4ccccc43)CCO2)n1 +CCCNC(=O)C1CCN(C(=O)c2ccc(C(C)(C)C)cc2)CC1 +COc1ccccc1NC(=O)c1nn2ccccc2c1Cl +CC(C(=O)Nc1ccc(Cl)cn1)N1Cc2ccccc2C1=O +CN(C)C(=O)COc1ccc2c3c(c(=O)oc2c1)CCC3 +Cc1c(NC(=O)COCC2CC2)c(=O)n(-c2ccccc2)n1C +COCCS(=O)(=O)NC1CCCN(c2ccccc2F)C1=O +CCn1nc(C)cc1C(=O)Nc1cc(Br)c(=O)n(C)c1 +O=C1CCCN1CCc1nc(Cc2cccs2)no1 +CNC(=O)c1sc2ccc(NC(=O)c3cnccn3)cc2c1OC +CCC(C)NC(=O)c1cc2sccc2n1CC +O=C(NCC1CCCO1)c1cccc(CNC(=O)C2CC=CC2)c1 +CCNc1cc(C(=O)N(C)c2ccccc2)ccn1 +Cc1ccc(NC(=O)c2cccc(OC(C)C)c2)c(N)c1 +CC(C)N(C(=O)c1ccc(C(F)(F)F)nc1)C1CCOCC1 +CC(=O)Nc1cccc(NC(=O)COc2cccc3[nH]ccc23)c1 +Cc1cc(Br)cn2c(C(C)O)cnc12 +O=C(c1nc2sccn2c1-c1ncc[nH]1)N1CCCCC1 +O=C1CC(c2nc(-c3cccnc3)no2)CN1c1ccc(F)cc1 +Nc1c(NCCC2=CCCCC2)ncnc1N1CCOCC1 +COc1cccc(CNC(=O)N(C)CCc2ccccn2)c1OC +CC(C)C(NC(N)=O)C(=O)NCc1cccc(Cl)c1 +O=C(C1CCC1)N1CCC(C(=O)N(Cc2ccccc2)C2CC2)CC1 +CCn1nc(C(=O)OCc2cccc(OC)c2)c2ccccc2c1=O +CCC(=O)Nc1nnc(C2CC(=O)N(c3ccccc3)C2)o1 +CCc1cc2c(=O)[nH]c(Cc3cc(C)on3)nc2s1 +Cc1noc(C2CCN(C(=O)NC3CCCc4ccccc43)CC2)n1 +CC(NC(=O)COc1ccccc1)c1ccc(S(N)(=O)=O)cc1 +O=C(Cc1ccc(-n2cccn2)cc1)Oc1ccc(-n2cnnn2)cc1 +CCc1noc(C(C)Oc2ccc(C#N)cc2OC)n1 +CC(=O)N1CCN(C(C)c2nc3ccccc3c(=O)[nH]2)CC1 +CS(=O)(=O)N1CCN(S(C)(=O)=O)C(O)C1O +CCCc1nn(CC(=O)NCCOC)c(=O)c2cc3ccsc3n12 +CCOc1ncccc1CNC(=O)c1n[nH]c2c1CCCC2 +CC(Cc1ccccn1)N(C)Cc1cc2ccccc2o1 +COCCNC(=O)c1nnc(C(=O)Nc2ccc(F)cc2)s1 +O=S(=O)(NCc1cccnc1)c1ccccc1F +CCCC(=O)Nc1nnc(-c2ccc(F)cc2F)o1 +COC(=O)c1sccc1OCc1cccc(C(N)=O)c1 +Nc1c(-n2cnc3ccccc32)ncnc1-n1cnc2ccccc21 +COc1cccc(OC)c1OCc1ccc(C#N)cc1 +N#Cc1cccc(C(=O)NCCSc2ccccc2)c1 +O=C(CSc1nnc2sc3ccccc3n12)NCC1CCCO1 +N#Cc1c(C2CCOC2)cc(-c2c(F)cccc2F)nc1N +Cc1ccc(-c2csc(NC(=O)Cn3ccnc3)n2)cc1C +CC(=O)c1cccc(NC(=O)CCn2cnc3sccc3c2=O)c1 +COc1ccc(Cl)cc1C(C#N)c1ccc(N)cn1 +COc1ccc(CCC(=O)N2CCNC(=O)C2c2ccccc2)cc1 +CC(C)CC(NS(=O)(=O)c1cccnc1)c1cccs1 +COCC(C)C(=O)Nc1cc(-c2ncco2)ccc1C +COCCCNC(=O)Nc1cccc(Cl)c1OC +Cc1cc(NC(=O)c2csc3c2CCCC3)n(C)n1 +O=C(CCc1ccccc1)NCCc1cccc(O)c1 +N#Cc1cccnc1NCCSc1ccccc1 +CC1CCCN(S(=O)(=O)N2CCCCC2c2ccco2)C1 +CC(C)CCCCCCC1OCC2=C1C(=O)OC2 +Cc1ccc(S(=O)(=O)N(C)CC(O)COc2ccccc2C)cc1 +Cc1cc(-c2cnnc(N)c2C(=O)NC2CC2)ccc1F +Cc1nc(Nc2ncnc(N(CCC#N)CCC#N)c2N)sc1C +CNC(=O)c1nn(-c2ccccc2)c(=O)cc1OC +CC(=O)NCc1ccc(S(=O)(=O)N(C)C(C)C)s1 +CNC(=O)NCC(=O)NC(Cc1ccccc1)C(C)(C)C +Cc1nc(NC(=O)c2csc(NCC(C)C)n2)sc1C +Cc1ccc(F)cc1C(N)C(=O)NCC(O)CO +Cc1ccc(NC(=O)c2ccc(-c3cccnc3)nc2N)cc1 +Cc1nc(-c2ccc(NC(=O)Cn3cccnc3=O)cc2)oc1C +N#CC(c1ccccc1)N1CCN(C(=O)c2ccc(F)cc2)CC1 +COc1ccc(S(=O)(=O)C2CN(C(=O)c3ccccc3F)C2)cc1 +N#Cc1cccc(S(=O)(=O)N2CCCc3ccccc32)c1 +CC1CN(CCNC(=O)c2cc(-c3ccco3)[nH]n2)CC(C)O1 +CC1CC(=O)Nc2c1c(NC(=O)Cc1ccccc1)nn2C +CC(C)(C)OC(=O)NCC1(N2CCOCC2)CCCC1 +CCn1cccc(-c2csc(NCCOC)n2)c1=O +CCC(CC)C(C(=O)Nc1ccc2c(c1)COC2)N1CCOCC1 +COc1ccccc1CN1CC(C(=O)Nc2cnn(C)c2)CC1=O +Cc1cccc(NC(=O)N2CCN(C(=O)c3nonc3N)CC2)c1C +Cc1noc(C)c1CN(C)c1ncnc2c1Cc1ccccc1OC2 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(-n3cccn3)cc2)cc1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NC(C)CCC1CCCC1 +CC(=O)c1cc(Br)cc(F)c1OCc1nncn1C +COC(=O)c1cccc(NCC(=O)N(C)C2CCCCC2)c1 +CC1CCCC(NC(=O)COC(=O)c2ccc3ccccc3n2)C1C +CC(C#N)CSc1ccccc1NCc1nsc(N(C)C)n1 +COCCn1cnnc1SCc1cccc(F)c1 +C=CCOC(=O)Cn1c(=O)sc2cccc(Cl)c21 +CSc1ccccc1NC(=O)NCc1cc(C)no1 +Cc1nc(C2(NC(=O)NC3C=CCCC3)CCC2)no1 +CCc1ccc(NC(=O)NCCc2c(C)nn(C)c2C)cc1 +O=C(CNC(=O)OCC(F)(F)F)NCc1ccc(Cl)cc1 +Cc1csc(CNC(=O)Nc2cnc3c(cnn3C(C)C)c2)n1 +N#Cc1ccc(NC(=O)c2nnc3ccccc3n2)cc1 +CCCOCC(=O)Nc1ccccc1-n1cccn1 +CC(NC1=NS(=O)(=O)c2ccccc21)c1ccc(F)cc1 +FC(F)(F)Cn1cc(NCc2cnc(-c3ccccn3)s2)cn1 +O=C(CCNC(=O)NCc1ccccc1)NC1CCCCC1 +O=C1OCCN1CCSc1nc(C2CCCC2)n[nH]1 +CC1CCCC(NS(=O)(=O)c2cccc3cnccc23)C1 +Cc1cc(C)c(C(=O)N2CCN(S(C)(=O)=O)CC2)c(C)c1 +Cc1cc(C)c(NC(=O)c2ccc(N)nc2)c(C)c1 +CN(C)C(=O)C1CCN(S(=O)(=O)N(C)C2CCCCC2)CC1 +CCCOc1nc(CC)nc(NC(C)(C)C)c1N +O=C(CCNS(=O)(=O)c1cccc(Cl)c1)N1CCC1 +CCOc1ncccc1C(=O)N1CCN(C(=O)c2ccoc2C)CC1 +CCC(C)NC(=O)C(C)NCc1nc2ccccc2n1C +C#CCOc1cc(F)ccc1NC(=O)NCC(C)(C)c1ccncc1 +CC(Oc1cccc(Cl)c1)C(=O)N1CCNC(=O)C1 +CC(C)N(CC(C)(C)O)C(=O)Nc1cnn(CC(F)(F)F)c1 +O=C(OCCCc1ccncc1)C1CC1(Cl)Cl +Cc1nc2nnc3c(=O)n(-c4ccc(F)c(F)c4)ccc3n2n1 +Cc1nc2nc(SCCOCCO)nn2c(C)c1C +O=C(NCCCn1cccn1)c1c[nH]nc1-c1ccccc1Cl +CC(C)c1ncc(CN2CCN(C(C)c3cccnc3)CC2)s1 +CCCC(C)C(=O)NC1CCCN(Cc2ccccc2)C1=O +CC(=O)N1CCc2ccc(S(=O)(=O)NCC(C)(C)O)cc2C1 +O=C(Nc1nc2c(s1)COCC2)c1ccc(OC(F)(F)F)cc1 +CCC1CNc2cc(S(=O)(=O)N3CCOCC3)ccc2O1 +CCOC(=O)c1c(NC(C)=O)nc(SC)n1Cc1cccs1 +COCCOc1ccc(Br)cc1NC(=O)c1ccoc1 +O=C(Nc1ccc(C(=O)N(CC(F)(F)F)C2CC2)cc1)NC1CC1 +COCc1ccc(C(=O)Nc2ccc(OC(F)F)c(F)c2)cc1 +CNS(=O)(=O)c1cccc(CNC(=O)N2CC(C)OC(C)C2)c1 +Cc1cc2c(cc1F)C(CSc1nnnn1C)NCC2 +CC(NC(=O)c1nn2ccccc2c1Cl)c1ccccc1 +O=C(CCn1cncn1)NCc1ccc(NC(=O)c2ccco2)cc1 +COCCn1cnnc1SCc1ccc(C#N)cc1 +COc1ccc(C2CC(=O)Nc3nc(N)ccc32)c(OC)c1OC +COc1ccc(F)cc1NC(=O)c1ccc(-n2cnnn2)cc1Cl +Cc1cc(C(=O)NCc2nnc3ccc(C(F)(F)F)cn23)on1 +Cc1cc(C(NCC(F)(F)F)C(N)=O)cc(C)c1O +CC(C)(C)c1ccc(SCC(=O)OCC(N)=O)cc1 +CCn1ncnc1C(C)NC(=O)Cc1csc(C)n1 +CCOc1ccccc1NC(=O)c1cc(CC)n2nccc2n1 +CCOC(=O)c1cccc(CSc2n[nH]c(N)n2)c1 +CS(=O)(=O)c1ccccc1C(=O)NCc1nc2ccccc2s1 +Cc1n[nH]cc1CNC(=O)CCc1cccc(N)c1 +Clc1ccccc1Cn1nnc(-c2cccs2)n1 +COc1ccc(OC)c(NC(=O)CSc2ncn[nH]2)c1 +CCC(CC)NC(=O)C1CCCN1C(=O)OC(C)(C)C +Cc1ccc(-c2noc(CCC(=O)Nc3ncccn3)n2)cc1 +O=C(c1ccc(F)cc1)N1CCOC12CCCCC2 +CCc1nonc1NC(=O)COc1ccc(F)cc1 +Cc1nnc(NC(=O)C2CNCc3c(C)cccc32)s1 +CCN(CC)C(=O)Cn1nc(-c2cccs2)c2ccccc2c1=O +COc1ccc(C)cc1NC(=O)CNC(=O)C1(C)CCCO1 +CC(C)OCCCNC(=O)c1cccc(N2CCCS2(=O)=O)c1 +Cc1ccc2c(c1)c(=O)nc1n2CC(=O)C1c1nc2ccccc2s1 +N#Cc1cccc(C(=O)N2CCOC(c3ccccc3)C2)c1 +CCOc1ccccc1NC(=O)c1snc(C#N)c1N +CC(=O)N1Cc2ccccc2CC1C(=O)NCC(C)C +COc1cccc(C(C)NC(=O)c2n[nH]cc2N)c1 +C#CCN1C(=O)C(c2ccccc2)Nc2cc(F)ccc21 +Cc1ccc(-c2nnn(CC(=O)N(C)CC(=O)N(C)C)n2)cc1 +COC(=O)CC(C)NC(=O)c1cccc(CC#N)c1 +CCCCN(CCCC)C(=O)c1ccc2c(c1)OCCO2 +CCC1COCCN1C(=O)c1cc(C(C)C)nc(N)n1 +O=C(OCc1nnc(-c2ccco2)o1)c1ccc(O)cc1O +FC(F)CN(Cc1cnc2ccc(Br)cn12)C1CC1 +Cc1ccc(SCC(=O)Nc2nnc(-c3cc(C)nn3C)o2)cc1 +Cc1nc(CNc2ccccc2SCCC#N)no1 +O=C1CCC(C(=O)Nc2ccc(Cl)c(F)c2)N1 +Cn1ccnc1C(CCc1ccccc1)OC(=O)c1cccnc1 +COc1ccccc1CCNS(=O)(=O)Cc1ccc(F)cc1 +CCOC(=O)C1CCN(C(=O)COc2ccc3c(c2)CCC3)CC1 +CNC(=O)NCC(=O)Nc1ccc(N2CCCCC2)cn1 +CCCOc1nc2c(c(=O)n(C)c(=O)n2C)n1CC +COc1ccc(C2(C(=O)NC(C)C)CCOCC2)cc1 +O=C(COc1ccccc1F)N1CCC(C(=O)N2CCCCC2)CC1 +Cc1nc(CSc2ncccn2)n(-c2ccc(F)cc2)n1 +CN(C)S(=O)(=O)N1CCc2nc(NC(=O)C3CCC3)sc2C1 +O=C1CN(Cc2nc(-c3ccc(F)cc3)no2)CCN1 +COc1ccc(CCNCc2cccc(F)c2)cc1 +Cc1cc(OCC(=O)Nc2c(C)cccc2C)c2cccc(F)c2n1 +COc1cccc(NC(=O)C2(C)Oc3cccnc3N(C)C2=O)c1 +Cc1nc(CN2c3cccc4cccc(c34)S2(=O)=O)cs1 +COc1ccccc1N(C)C(=O)Cn1ccc(=O)c2ccccc21 +CCc1ncc2c(n1)CN(c1cc(C(=O)N3CCCCC3)ccn1)C2 +CN(C)c1ccc(NC(=O)c2cc(F)c(F)cc2Cl)cn1 +COc1ccc(F)c(NCc2cccc(S(=O)(=O)N(C)C)c2)c1 +CC(=Cc1ccc(F)cc1)c1nc(-c2ccc(C#N)cn2)no1 +CN(CCCc1ccccc1)C(=O)Cn1c(=O)cnc2ccccc21 +O=C(N1CCN(c2ncccn2)CC1)C1(c2ccc(Cl)cc2)CC1 +Cc1ccsc1C(=O)NC(CC(C)C)C(=O)N(C)C +CC(=O)Nc1ccc(NC(=O)c2c(F)cccc2Cl)c(Cl)c1 +COc1ccc(NC(=O)N2CCOCC2C)cc1 +C=CCc1ccccc1OCC#CCNS(=O)(=O)CC +COCc1ccc(CNS(=O)(=O)c2cc(C)ccc2C)cc1 +COc1cccc(C(=O)N(Cc2cccnc2)CC2CCCO2)c1F +CN1CC(C(=O)Nc2cccc(C(=O)c3ccccc3)c2)CC1=O +C=CCNC(=O)c1noc2c1CCc1cc(OC)ccc1-2 +Cn1nnnc1-c1cccc(C(=O)Nc2ccon2)c1 +O=C(NC1CC1)c1nnc(N2CCCCC2)c2ccccc12 +CCS(=O)(=O)N1CC(n2nc(-c3ccccc3)ccc2=O)C1 +CCC(C(=O)NCc1n[nH]c(=O)c2ccccc12)c1ccccc1 +COC(=O)C(C)NC(=O)C(C)Oc1ccc(C)cc1Br +CCc1cc(C(=O)NCCc2ncc(C)s2)sc1C +O=C(Nc1ccc(F)nc1)N1CCCC1CN1CCOCC1 +C=CCN(Cc1cccs1)C(=O)Cn1ncc(=O)c2ccccc21 +CCn1nc(C(=O)NC(C)(C)C)c(=O)c2ccccc21 +Cc1nc(C(C)NC(=O)N2CCC(OCCC(C)C)C2)cs1 +COc1ccc(C(=O)OCC(=O)Nc2c(C)cccc2C)cc1F +Cc1ccc(C)c(S(=O)(=O)NC(C#N)c2cccnc2)c1 +COc1ncccc1NC(=O)Cc1csc(C(C)(C)C)n1 +CCCC(=O)N=c1sc2cc(S(C)(=O)=O)ccc2n1C +Nn1c(SCc2ccccc2)nc2ccccc21 +N#Cc1ccc(N2CC3CN(c4cccnc4)C(=O)C3C2)nc1 +CCNC(=O)c1cnc(-c2ccc(Cl)cc2)nc1N +CC1CCC(NC(=O)Nc2ccc3c(c2)NC(=O)CS3)CC1 +CCOC(=O)C1=C(CNc2ccc(C)c(Cl)c2)NC(=O)NC1 +COCCNC(=O)Nc1ccc(Oc2cccnc2)c(C)c1 +COC(C)(C)c1noc(-c2cccc(NC(=O)NC3CC3)c2)n1 +COc1ccccc1S(=O)(=O)NCCNc1cccc(F)c1C#N +CCOc1ccccc1NC(=O)COC(=O)c1c[nH]c2ccccc12 +O=C(c1cnc(-c2cccnc2)nc1)N1CCOC(c2ccccc2)C1 +CCOC(=O)c1c(C)cccc1NC(=O)c1cccs1 +CC(C)N1CC(C(=O)Nc2cc(F)c(F)c(F)c2)CC1=O +CCOC(CC)C(=O)Nc1ccc(C(=O)NC(C)C)cc1 +COC(=O)N1CCC(NC(=O)c2ccc(-n3cnnn3)cc2)C1 +O=C(Oc1ccc(C(F)(F)F)cc1)C1CCOCC1 +COCCOc1ccccc1NC(=O)c1ccc(-n2ccnn2)cc1 +O=C(c1cccs1)N1CCN(Cc2nc3ccccc3s2)CC1 +O=C(NCc1ccccc1)N(Cc1ccco1)CC1CCCO1 +COCCNC(=O)c1cc(Cl)c(OC)c(OC)c1 +CCC(=O)Nc1cccc(NC(=O)CCc2nc(C(C)C)no2)c1 +Cn1c(SCC(=O)NC2CCCCC2)nnc1-c1ccccc1O +Cc1noc(C)c1CC(C)NC(=O)NC1(C)Cc2ccccc2C1 +Cc1cc(C)c2nc(C)cc(C(=O)N(C)CCc3cnn(C)c3)c2c1 +Cc1ccc(C(C)NC(=O)NCC(C)(C)N2CCOCC2)cc1F +CC(C)NC(=O)CN(C)S(=O)(=O)c1cccs1 +CNS(=O)(=O)c1ccc(CNC(=O)c2ccc(F)c(F)c2)cc1 +CCc1nc2ccccc2n1CC(=O)NCC(C)C +COCc1cc(C(=O)OC)nc(N2CCC(C)CC2)n1 +Cc1cc(C(=O)N2CCN(c3cc(Cl)ccc3C)CC2)c(C)o1 +COc1ccc(C(=O)Nc2cccc(C)n2)c(OC)c1 +COc1ccc(S(=O)(=O)NCCC(O)c2ccccc2)c(C)c1 +COC1CCN(c2ccc(F)cc2CN(C)c2nccc(C)n2)CC1 +Cc1cc(S(=O)(=O)Nc2cccnc2)ccc1Br +CC(C)CNC(=O)Nc1ccc(C(=O)NCC(C)C)c(Cl)c1 +COCC(C)NC(=O)CN1CCN(c2ccc(C(C)C)cc2)C1=O +c1cncc(-c2nc(-c3ccc4c(c3)OCCO4)cs2)c1 +COC(=O)c1ccc(NC(=O)CC(NC(C)=O)c2ccccc2)cc1 +COc1cc(C#N)ccc1OS(=O)(=O)c1ccc(F)c(F)c1F +O=C(CCn1cncn1)Nc1nnc(C(F)(F)F)s1 +N#Cc1ccc(OCc2nnnn2-c2ccccc2)c(Cl)c1 +Cc1nn(C)c2ncnc(NCCc3nccc(-c4ccccc4)n3)c12 +COC(=O)Cc1c(C)nc(N2CCCCC2)nc1C +Cc1nc(CC(=O)OCCOc2ccccc2F)cs1 +COc1ccc(C2CC(O)=Nc3c2c(=O)[nH]n3C(C)C)cc1 +CC(C)(C)C(NC(=O)CCn1ccccc1=O)c1ccccc1 +CS(=O)(=O)N1CCCCCC1c1cccs1 +CC(C)(C)OC(=O)N1CCC(Nc2ncccc2C#N)CC1 +Cc1ccc(C(=O)NCC(=O)c2ccc(F)c(F)c2)cc1C +Cc1ccc2ncc(C(=O)N(C)c3ccc(F)c(F)c3)n2c1 +O=C(CSc1nnnn1C1CCCCC1)Nc1ccccc1F +CCOC(=O)C1CCN(C(=O)c2n[nH]c3c2CCC3)CC1 +COc1ccc(-n2nnnc2SCC(=O)N2CCC(C)CC2)cc1 +CN(Cc1ccccc1C(F)(F)F)C(=O)c1cccc2cn[nH]c12 +Cc1cc(C(=O)NCC(C)c2nc(-c3ccccc3)no2)c(C)s1 +COC(=O)c1ccccc1NC(=O)c1ccc(OC)c(OC)c1 +CCc1[nH]c(C(=O)NCCc2ccccc2F)c(C)c1C(=O)OC +O=C(CC1C=CCC1)NC(Cc1nccn1C(F)F)c1ccccc1 +COCCN(Cc1ccoc1)C(=O)c1cc(C)oc1C +CC(C)C(=O)NCCNC(=O)Cc1cccc2ccccc12 +CN(C)C(=O)N1CCc2c(nnn2C)C1COCC1CC1 +CC(=O)c1cccc(S(=O)(=O)NCC(O)c2cccs2)c1 +OCCNc1cc(N2CC3C4CCC(C4)C3C2)ncn1 +CSc1ccccc1C(=O)Nc1ccc(C)cn1 +Cc1noc2nc(C(C)C)cc(C(=O)Nc3ccncc3)c12 +CCCCc1nnc(NC(=O)Cc2cccc(F)c2F)s1 +CC(C)(C)c1nnc(SCc2ccccc2C#N)o1 +CN1C(Cc2cccc3[nH]ccc23)C(O)c2ccccc2S1(=O)=O +C=CCNC(=O)c1ccc(NC(=O)C2(O)CCCC2)cc1 +Cn1nc(C(=O)NCC2CCCO2)cc1NC(=O)C1CCCC1 +Cc1cc(NCc2cccc(OC(F)F)c2)no1 +COc1ccc(C(=O)Nc2ccc(F)c(N)c2)c(OC)c1 +CC(CC1CCCCC1)C(=O)N1CCCC(C(N)=O)C1 +COCCNC(=O)Nc1ccccc1C(=O)N1CCCCC1 +COc1cc(C(=O)N(C)Cc2ccc(C#N)cc2)cc2c1OCCO2 +O=c1[nH]c(CC2CC2)nc2cc3ccccc3cc12 +O=C(Nc1cccc(F)c1)C1CC1c1ccccc1 +Cc1cccc(C(C)C)c1NC(=O)CCN1CCOCC1 +CC(O)CCN(C)C(=O)NCC1(c2ccccc2Cl)CC1 +COc1cc(Cl)c(CNC(=O)c2ccc(F)cc2)cc1OC +O=c1[nH]nc(CSc2nnc(-c3cc4ccccc4o3)o2)[nH]1 +Cc1cnc2n(c1=O)CC(C(=O)NCC(C)O)CS2 +Cc1nn(C)c(C)c1-c1cc(C(=O)NCCc2ccccn2)n[nH]1 +CCS(=O)(=O)c1ccc(NC(=O)c2ccccc2F)cc1 +COC(=O)c1ccc(C(=O)N2CCCC2c2cc(C)on2)cc1 +CC(C)(C#N)NC(=O)C1CCN(C(=O)c2cccc3ccccc23)CC1 +O=C(Cc1ccc(O)cc1)Nc1c[nH]cc(Br)c1=O +Cc1nnnn1CC(=O)N(C)Cc1cccc(C(F)(F)F)c1 +O=S(=O)(c1cnn(C2CCOC2)c1)N1CCCCC1CO +CC(=O)Nc1c(-c2ccccn2)nsc1C(=O)NC1CC1 +Cc1cccc(C(=O)Nc2ccc3c(c2)CC(=O)N3C)c1 +Cn1c(C(=O)N2CCC(C3OCCO3)CC2)c(Cl)c2ccccc21 +Cc1ccc(CN2CCc3ccc(Cl)cc3C2)nc1 +Cc1ccc(C)c(S(=O)(=O)NCCNC(=O)Cn2cnnn2)c1 +COc1cc2c(cc1O)CCNC2c1ccc(F)cc1 +Cc1c(C#N)c(SCC(=O)N2CCCCC2C)nc2c1CCC2 +COc1ccc(-n2ccc(NC(=O)c3ccc(F)cc3F)n2)cc1 +COc1ccc2c(ccn2CC(=O)N(C)C(C)C)c1 +CN1C(=O)CCC(C(=O)NCC2CCC2)C1c1cccc(F)c1 +CCNC(=O)c1ccc(Cl)cc1NC(=O)c1cccnc1 +COCCN(CC(C)C)C(=O)NCC(F)(F)F +COC(=O)C(NCCO)c1ccc(Br)cc1 +CCc1ccccc1NC(=O)c1nnn(-c2ccccc2)c1N +CC(=O)c1ccccc1NC(=O)c1cncc(Br)c1 +COc1ccc(NC(=O)c2c(NC(C)=O)sc3c2CCC3)cc1 +O=C(Cc1csc(-c2cnccn2)n1)N1CCN(CCO)CC1 +COC(=O)c1c(-c2ccc(Cl)cc2)noc1N1CCOCC1 +O=C(CCOCC(F)(F)F)NCc1ccc2c(c1)OCCCO2 +CCc1ccc(C2c3c(O)n[nH]c3CC(C)(O)C2C(=O)OC)cc1 +CC(C)c1cc(NC(=O)CSc2ccc3c(c2)OCCCO3)on1 +CCC(CC)C(NC(=O)NCc1cnn(C)c1)c1ccccc1 +Cc1ncc(CN(C)C(=O)c2n[nH]cc2N)s1 +Cc1cc(C)cc(NC(=O)C(C)S(=O)(=O)c2ccc(O)cc2)c1 +C=CCOc1ccc(C(=O)Nc2ccc(C#N)cc2)cc1 +COC(=O)c1ccc(CCNC(=O)Cc2cccc(F)c2)cc1 +Cc1csc(NC(=O)c2ccccc2OC(F)F)n1 +COCCC(=O)N1CCC(c2nc3ccccc3cc2N)CC1 +COc1ccccc1CC(=O)N1CCC(C(N)=O)c2ccccc21 +COC(=O)C=C(C)c1sc(C)nc1-c1cccs1 +COc1ccc(CN(C(=O)NC(C)C2CCCO2)C2CC2)cc1 +Brc1cc(-c2ccncc2)cc2occc12 +Cc1ccccc1-c1nnc(SC2CC(C)OC2=O)n1C +Cc1ncccc1Oc1ncnc(N2CCCC(O)(CO)CC2)c1C +O=C(NCC1CCCO1)Nc1cccc2c1OC(F)(F)O2 +N#Cc1c(-c2ccc(Cl)cc2)nc2sc(C3CC3)nn12 +CCCCc1cc(NC(=O)Cc2ccsc2)[nH]n1 +CC1CCN(c2nc(N3CCOCC3)nc(N3CCOCC3)n2)CC1 +Cc1nc(C)c2c(n1)CCN(Cc1ccoc1)CC2 +CC(=O)N(C)C1CCN(C(=O)OC(C)(C)C)CC1 +CCOC(=O)C1CCCN(S(=O)(=O)c2ccccc2)C1 +CCc1cccc(CC)c1NC(=O)c1ccn(C)c(=O)c1 +CCOCCC(=O)N1CCCC1c1nnc2n1CCCCC2 +CC1CCCCC1NC(=O)COc1ccc(C#N)c(F)c1 +CCCc1nc(CN2CCOC(Cn3cccn3)C2)no1 +Cc1csc(SCc2noc(-c3ccccc3)n2)n1 +COc1ccc2c(C(=O)NCc3cccc(F)c3)cc(=O)oc2c1 +COc1cc(CNC(=O)NC2CCCCC2)ccn1 +CCc1cc(C(=O)NC(C)c2nc3ccccc3o2)n(C)n1 +CNC(=O)CCC(O)c1ccc(OC)c(OC)c1 +Cc1ccc(Cc2nc(C(=O)Nc3nn(C)cc3C#N)cs2)cc1 +CN1C(=O)COc2ccc(NC(=O)c3ccc(F)cc3)cc21 +CCS(=O)(=O)c1nc2ccccc2n1CC(=O)N1CCCCC1 +O=c1c2ccccc2ncn1CCc1ccccn1 +Nc1cc(Cl)ccc1NC(=O)c1ccccc1N +COC(=O)C(C)(C)Oc1ccccc1Br +CCCCc1nnc(NC(=O)c2ccc[nH]c2=O)s1 +FC(F)Oc1cccc2c1CCNC2C1CCCO1 +CCCC(=O)Nc1cccc(NCc2nnc(C(C)(C)C)o2)c1 +CCc1cc(NC(C)CN2CCOCC2)ncn1 +COc1ccc(C(=O)OCc2ccccc2)cc1OC +Cc1ccnc(NCc2nc(-c3ccncc3)n[nH]2)n1 +COc1cc(C)c(C(=O)NC2CCCCC2)cc1OC +COCCNC(=O)N1CCC(c2cc(-c3ccc(F)cc3)n[nH]2)CC1 +CC(C)C(Sc1nnc2ccccn12)C(=O)NCc1cccnc1 +Cc1ccc(-c2nnc(NC(=O)c3c(C)cnn3C)o2)c(C)c1 +CCC(=O)NCC(Cc1cccc(F)c1)N1CCCC1=O +CCOc1cc(C#N)ccc1OCc1nnc(-c2cccs2)o1 +CCCNC(=O)C1CCN(C(=O)c2ccc(O)cc2F)CC1 +CCOC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +N#CCOC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 +COCC(NC(=O)CNc1ccccc1)C(C)C +Cc1nc(SCc2ccc(C(N)=O)cc2)n(CC(C)C)c1C +COc1cc(Cl)c(S(=O)(=O)NCCO)cc1Cl +CC(Cc1ccccc1F)C(=O)NCc1cn(-c2ccccc2)nn1 +CCC(CC)C(=O)NC1CCN(S(=O)(=O)c2cnn(C)c2)CC1 +COc1ccc(OC)c(CN(C)C(=O)Cc2ccc[nH]2)c1 +COc1cc(C#N)ccc1Oc1ccc(NC2CC(C)OC2=O)cc1 +Cc1cc(C(C)NC(=O)C(C)Oc2ccc(C#N)cc2)c(C)s1 +Cc1ccccc1OC(=O)Cc1c(C)nn(CC(C)C)c1C +CC(=O)Nc1ccc(Br)cc1NC(=O)c1ccccc1C +Cc1cccc(OCCCC(=O)Nc2cccc(N)c2)c1 +Nc1cc(S(=O)(=O)NCCCO)ccc1Cl +Cc1nn(CCc2c[nH]c3ccccc23)c(C)c1N +c1csc(C(CNc2ncnc3[nH]cnc23)N2CCOCC2)c1 +Cc1cc(C(=O)COC(=O)c2ccccc2O)c(C)n1C1CC1 +COc1cc(CN(C(=O)c2ccccc2C)C2CC2)ccc1O +O=C(Cn1cccn1)OCC(=O)c1ccc2ccccc2c1 +NS(=O)(=O)NC1CCN(C(=O)c2ccoc2)CC1 +COc1cc(NC(=O)C2CC2)ccc1N1CCCCC1=O +Cc1cc(C(=O)OC(C)C)c(NC(=O)c2ccncc2)s1 +Cc1cc(C(=O)NCCc2csc(-n3cccn3)n2)c(C)o1 +O=C(NCCCNC1=NS(=O)(=O)c2ccccc21)c1ccncc1 +CC(C(=O)N1CCC2(CC1)Nc1ccccc1NC2=O)n1ccnc1 +CN(CC(=O)N1CCNCC1)C(=O)C1CC=CCC1 +O=C(NCC(=O)N1CCN(C2CC2)CC1)NC1CC1 +COCc1cccc(CNC(=O)Cn2cnnn2)c1 +Cc1cc(CNC(=O)NC23CC4CC(CC(C4)C2)C3)c(C)o1 +CCOc1ccc2[nH]cc(C(=O)NCc3cccs3)c(=O)c2c1 +Cc1c(C(=O)NC2CC2)cccc1N(C)S(C)(=O)=O +CCCCNS(=O)(=O)c1ccccc1C#CCCO +CN(CCNC(=O)C1CCN(c2ncccn2)CC1)c1ccccc1 +O=C(NC(CO)c1ccccc1)c1ccc(F)c(F)c1 +CC1CCCC(NC(=O)NC(C)c2ccc(C#N)cc2)C1 +Cc1ccc(CC2Oc3ccc(N)cc3N(C(C)C)C2=O)cc1 +CCN(Cc1cnn(C)c1)C(=O)Nc1ccc(F)c(Cl)c1 +COC(=O)NCC(=O)NCC(C)Oc1ccccc1 +CCn1nc(C(=O)N2CC3CCC2CN(C(=O)C2CCC2)C3)cc1C +Cc1cc(C(=O)N2CCOCC2C2CC2)ccc1Cl +COc1ccc(NC(=O)c2cccc(F)c2N)c(OC)c1 +Cc1ccc(C(=O)c2ccc(N3CCOCC3)o2)cc1 +CC(C)c1cc(NC(=O)CSc2ccc3c(c2)OCCO3)on1 +CSc1nnc(CCCNC(=O)c2cnccn2)n1C1CCCC1 +Cc1ccc(NC(=O)CNc2ccccc2C(N)=O)cc1Cl +CC(OC(=O)c1cc2ccccc2o1)C(=O)NCc1ccco1 +COc1ccc(N)cc1OCC(=O)Nc1ccc(F)cc1 +CCc1cc(=O)n(CC(=O)Nc2cccc(OC)c2)c(N)n1 +CC(NC(=O)c1cccc2ccccc12)C(=O)N1CCOCC1 +Cc1ccccc1CC(=O)Nc1ccc2c(c1)OCCO2 +CCOc1cc(C)ccc1NCC(=O)N1CC(=O)Nc2ccccc21 +NC(c1cc(Cl)ccc1Cl)C(F)(F)C(F)(F)F +COc1ccc(C(=O)Nc2cccn3nc(C)nc23)cc1 +OCc1ccc2nc(-c3ccc(F)c(F)c3)oc2c1 +CN(CC1CCCC1)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +C=CCNC(=O)C1C2CCC(C2)C1c1nc(Cc2ccccc2)n[nH]1 +Cc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c(O)c1C +Cc1cnn(C2CN(c3cc(C)nc4nc(C(F)(F)F)nn34)C2)c1 +C=CCSc1n[nH]c(=O)n1-c1cccc(Cl)c1 +Cc1ccc(C)c(-n2nnnc2SCC(=O)Nc2cc(C)on2)c1 +N#Cc1ncn(CC(=O)Nc2ccc(Br)cc2Cl)n1 +CCc1cc(C(=O)NCC2CCCO2)cc(=O)[nH]1 +C=CCN(CCO)S(=O)(=O)c1ccc(F)c(C#N)c1 +Cc1ccc(-c2nc3sc(C4CC4)nn3c2C#N)c(C)c1 +Cc1cc(C)cc(C(C)Nc2ncc(S(N)(=O)=O)s2)c1 +Cc1nc2cc(C(=O)N3CCN(C(=O)CO)CC3)ccc2n1C +COCc1ccccc1NC(=O)C1COc2ccc(F)cc2C1 +C=CCOC(=O)c1cccc(CS(=O)(=O)c2ccccc2)c1 +COc1ccc(C(=O)Nc2ccccc2OC)nn1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1ccc2c(c1)OCO2 +CCNC(=O)c1ccc(NC(=O)c2ccc(C)cc2)c(C)c1 +COCCCN(C)C(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +CCc1noc(CC)c1CNC(=O)c1cccc(S(C)(=O)=O)c1 +Cc1c(CN(C)C(=O)c2ccccc2F)cnn1C +COc1ccc(C(=O)Cn2c(=O)n3nc(C)nc3c3ccccc32)cc1 +COc1ccc(NC(=O)NCc2ncc[nH]2)cc1OCC(F)(F)F +CCNC(=O)CNC(=O)Nc1ccc(C(=O)N2CCCCCC2)cc1 +Cc1cc(=O)c(C(=O)N(C)C)nn1-c1ccccc1C(F)(F)F +O=C(Cc1ccc(F)c(F)c1)Nc1ccc(N2CCNC2=O)cc1 +CC(=O)OCCc1c(C)nc2c(C#N)cnn2c1N1CCCC1 +CC(C)Nc1nnc(SCC(=O)NC2(C#N)CCCCC2)s1 +CCSc1cc(C(=O)NCC(=O)N(C)C)ccn1 +Cc1cccc(C(=O)Nc2nc(C(F)(F)F)cs2)n1 +Cc1ccc(C(=O)NCC(=O)NC2CCCOC2)s1 +Nc1cccc(-c2cc(=O)[nH]c(CCc3ccccc3)n2)c1 +Cc1ncc(-c2ccncc2)c(C2CCCN(C(=O)C(C)(C)C)C2)n1 +COc1ccc(F)cc1Cc1nc(C)c(C(C)=O)s1 +CC1CC(C)CN(C(=O)CNC(=O)c2ccc(N)cc2)C1 +CCCn1ccc2ccc(NC(=O)NCC(=O)NC3CC3)cc21 +Cc1ccc(NC(=O)NCCCN2CCOCC2)cc1-n1cnnn1 +O=C(NCC1CCOCC1)c1ccc(Br)cc1 +COC(=O)COc1cccc(NC(=O)Nc2ccc(F)cc2)c1 +CC(=O)Nc1ccc(SCC(=O)Nc2cc(C)ccc2C)nn1 +O=C(c1cc2c(F)cccc2[nH]1)N1CCC(CN2CCOCC2)CC1 +COCC(O)CN(C)S(=O)(=O)c1ccc(OC)cc1 +COc1ccc(N)cc1NS(=O)(=O)c1ccccc1F +Cc1ccc(CC(=O)NCc2cscn2)s1 +Nc1ccccc1CN1CCN(c2ncccn2)CC1 +O=c1c2ccccc2nnn1CC(O)c1cccc(C(F)(F)F)c1 +CCCNC(=O)CNc1cc(C(=O)N2CCOCC2)ccc1C +Cc1cccc(NC(=O)COC(=O)c2cc(=O)[nH]c3ccccc23)c1 +COc1ccc(C)cc1C(C)NC(=O)c1cccc(S(C)(=O)=O)c1 +Cc1nc(NCCNC(=O)C2CCCC2)cc(N2CCOCC2)n1 +CCn1c(CNC(=O)c2cc(-c3ccco3)on2)nc2ccccc21 +CC1(C)CC(=O)c2c(csc2S(C)(=O)=O)C1 +Nc1nc2c(c(=O)[nH]1)C(c1ccc3ccccc3c1)CC(=O)N2 +CCCn1cnc2scc(-c3ccc(OC)c(OC)c3)c2c1=O +CCCCC(NC(=O)c1csc(C)n1)c1ccc(OC)cc1 +COC(=O)CCCNC(=O)c1ccc(Br)cc1O +Cc1ccc(C)c(NC(=O)c2cc(-c3cccnc3)on2)c1 +CC(=O)c1cccc(S(=O)(=O)N(C)CC(N)=O)c1 +CCOc1c(OC)ccc2c1CCNC2c1ccncc1C +CCOC(=O)C1CCN(C(=O)CSc2ccccc2)CC1 +Cc1c(-c2cccc3cccnc23)ccc2nc(N)nn12 +CC(C)CCNC(=O)N1CCN(C(=O)N2CCOCC2)CC1 +CC(C)=CC1C(C(=O)N(C)Cc2cnn(C)c2)C1(C)C +CC(=O)Nc1cc(NC(=O)COc2cc(C)ccc2C)ccc1C +CCOC(=O)C1CCCN(S(=O)(=O)c2cncc(N)c2)C1 +Cc1nccn1-c1ccc(NC(=O)c2cnoc2-c2ccco2)cn1 +O=C(c1cccc(-c2ccoc2)c1)N1CCC2(CCC2)C1 +CN(Cc1c(F)cccc1Cl)C(=O)CNc1ccc(C(N)=O)cc1 +CCOCCCNC(=O)Nc1ccc(-n2nc(C)cc2C)c(F)c1 +O=S(=O)(Nc1cn[nH]c1)c1ccc(OC2CCCC2)cc1 +Cc1nc(SCC(O)c2ccc(F)c(F)c2)c2ccccc2n1 +Cn1cc(C(=O)Nc2cc(F)cc(F)c2)c(=O)c2cccc(Cl)c21 +Cc1ccccc1N1CCC(C(=O)NCc2cccnc2)C1=O +O=C(NCc1ccccn1)c1c[nH]c2ccc(F)cc2c1=O +CCN(CCO)C(=O)C1CC(=O)N(Cc2ccc(C)cc2)C1 +CCOc1ccccc1NC(=O)C(C)N1CCc2cc(F)ccc2C1 +CC(C)c1ccc2[nH]c(=O)c(CNc3cc(O)ccc3O)cc2c1 +CC(C)CCCCNC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +COCC(NC(=O)Cc1c[nH]c2cccc(C)c12)C(N)=O +COCC(C)NC(=O)C1CCN(c2ccc(Cl)c(Cl)c2)C1=O +Cc1ccc(CNS(=O)(=O)c2cccc(C#N)c2)cc1 +Cc1cc(NC(=O)NCCc2nc(-c3ccccc3)oc2C)n(C)n1 +CNc1nnc(-c2c(C)oc3c2CC(C)CC3)s1 +Cc1ccc2[nH]c3c(=O)n(CC(=O)N4CCCC4)ncc3c2c1 +CSc1nnc2c(n1)[nH]c1ccc(Cl)cc12 +O=C(NC1CCCCC1)C1CC(O)CN1C(=O)Nc1ccccc1 +Cc1nc(-c2cc(C)n(CC(=O)N3CCCCC3C)c2C)cs1 +CCC(C)NC(=O)c1ccc(NC(=O)Cn2ccccc2=O)cc1 +O=C(NCCOc1ccc(F)cc1)c1ccc(N2CCOCC2)nc1 +Cc1nn(C)c(C)c1OCC(=O)Nc1cccc(-c2cnco2)c1 +CCC(C)OCC(=O)N1CCCCC1CC(N)=O +CCN(CCO)C(=O)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 +CC(=O)Nc1cccc(NC(=O)N2CCCC(C)C2)c1C +O=C(NC1CC1)C(Sc1ccccn1)c1ccccc1 +CCCCNC(=O)c1cn2cc(-c3cc(C)oc3C)n(C)c(=O)c2n1 +Cc1cc(S(=O)(=O)c2ccc(N)cc2)ccc1F +O=C(NCc1ccc(F)cc1)c1ccc2c(c1)C(=O)CCCO2 +NC(c1ccc(F)cc1)c1nc(Cn2cncn2)n[nH]1 +O=C(NCc1ccco1)N1CCC(Oc2ccccc2)CC1 +CCOC(=O)c1cnc(NCc2cccnc2)s1 +COc1cc(OC)cc(C(=O)OCC(=O)Nc2ccc(C)cc2)c1 +CC(C)COC(C)C(=O)NC(C)c1nnc2n1CCCCC2 +Cc1noc(C)c1CCC(=O)Nc1cc(CCc2ccccc2)n[nH]1 +CCCN(CC(=O)NC)c1cccc(F)c1C(C)O +CC(=O)c1cc(C(=O)N(C)Cc2ccccn2)n(C)c1 +CCNC(=O)C1CCCN(C(=O)c2c(C)cc(C)cc2C)C1 +O=C(NCCCC(=O)N(C1CCCC1)C1CC1)c1ccccc1 +O=C(Nc1ccncc1)c1cc(-c2ccccc2F)on1 +O=c1c2ccc(F)cc2ncn1Cc1ccc(F)cc1 +Cc1csc(CNC(=O)CNC(=O)c2ccc(C)s2)n1 +Cc1cncc(NC(=O)N2CCCC2CN2CCOCC2)c1 +Cn1cc(N)nc1-c1ccccc1Br +CC(Cc1c(Cl)cccc1Cl)NC(=O)c1ccnn1C +O=C(NCc1nnc2ccccn12)NC1CCCC1 +Cc1ccc(NC(=O)c2cccc(N(C)C)c2)nc1 +CN(Cc1cccc(C#N)c1)C(=O)CCOc1ccccc1F +Cc1cc2oc(=O)cc(CNc3c(C)cccc3C(N)=O)c2cc1C +O=C(Nc1ccc(F)cc1F)c1cn2ccccc2n1 +CCc1ccc2c(CSc3ncn[nH]3)cc(=O)oc2c1 +Cc1ccc(C(=O)Nc2nc3cc(N)ccc3s2)cc1 +NC(=O)C1CCN(C(=O)CCc2cccc(F)c2)C1 +CCOc1cc(C#N)ccc1OCC(=O)N1CCCc2ccccc21 +CCOC(=O)c1c(NC(C)(C)C)sc(C(C)=O)c1N +COc1cccc(C(NC(=O)c2ccncc2)c2nccn2C)c1 +COc1c(CNCc2ccc(-n3ccnc3C)nc2)c(C)nn1C +CCOC(=O)CCCC(=O)c1cccc(F)c1F +CCCN(C(=O)c1cnn(CC)c1)C(C)c1cc2ccccc2o1 +COCCn1c(C(C)C)nc2cc(Cl)ccc21 +COc1ccc(CNC(=O)N(C)CC(C)(C)O)cc1OC +CC(NC(=O)c1ccc(OC(F)(F)F)cc1)c1ccncc1 +Cc1ccccc1S(=O)(=O)N(CCC#N)C(C)C +CC(C)n1cc(NC(=O)c2cccc(-c3nnnn3C)c2)cn1 +CCn1c(-c2ccccc2)nnc1S(=O)(=O)Cc1ccccc1F +CC(=O)c1ccc(N(CCCO)C(C)C)c(F)c1 +O=c1[nH]c2ccccc2cc1CNCCc1nnc2ccccn12 +CC(=O)OC(C(=O)N1CCC(C)CC1)c1ccccc1 +CCCc1cc(=O)n(CC(=O)Nc2ccc(C)cc2)cn1 +Cc1cc(C)c2ncn(C(C)Cc3cccnc3)c(=O)c2c1 +Cc1ccc(N2CC(C)N(C(=O)Cc3ccccc3F)CC2=O)cc1 +CC(NC(=O)c1ccco1)c1ccc(-n2cccc2)cc1 +Cc1nc(C(=O)NCCCN(C)c2ccccc2)cs1 +O=C1CCC(NCc2cccnc2)C(c2cc(F)cc(F)c2)N1 +CC(C)N(CCCNC(=O)c1cccc(Cl)c1)S(C)(=O)=O +CC(C)NC(=O)Nc1ccc(NC(=O)Cc2ccc(F)cc2F)cc1 +C#CCN1CCN(C(C)c2cn(-c3ccccc3)nn2)CC1 +CCCC(O)(CCC)CNC(=O)c1cnc2ccc(C)cn12 +COc1ccc(F)c(NC(=O)C(C)OCc2ccccc2)c1 +CCOC(=O)C(Cc1nc2ccc(OC)cc2n1C)NC +O=C(Cc1nc(Cc2ccc(F)cc2)n[nH]1)Nc1ccccc1 +Cc1cccc(N2CCN(C(=O)Cc3n[nH]c4ccccc34)CC2)c1 +NC(=O)c1cccc(NC(=O)Cc2ccc3ccccc3c2)c1 +CC(=O)c1ccc(NC(=O)NCCC(=O)N(C)C)cc1 +COC(=O)CNS(=O)(=O)c1cccc(C#N)c1 +CC1(Cc2ccc3c(c2)OCO3)CCC(=O)N(CC2(CO)CC2)C1 +Cc1ccc(CNC(=O)NCC(=O)NCc2cccc(F)c2)cc1 +CCn1cnnc1CNC(=O)Cn1ccc2cc(OC)ccc21 +COc1ncc(NC(=O)Cc2ccc(F)cc2)c(OC)n1 +Cc1sc2ncnc(N3CCCC3c3cccnc3)c2c1C +O=C(Nc1ccon1)Nc1cccc(Cl)c1Cl +CCc1nc2sc(C(=O)OCc3ccccc3)c(C)c2c(=O)[nH]1 +COC(=O)C1CN(CCc2ccc(Cl)cc2)CCC1=O +COC(=O)Cn1nc2c3cc(OC)c(OC)cc3ncn2c1=O +Nc1ccc(C(O)COc2cc(F)cc(F)c2)cc1 +CNC(=O)c1ccc(NC(=O)CCc2ccc(F)c(F)c2)cc1 +COC(=O)c1ccc(NC(=O)c2cc(C)n3nc(C)cc3n2)cc1 +CC(=O)c1sc(NC(=O)COc2ccccc2C)nc1C +Cc1c(NC(=O)c2cc[nH]n2)cccc1S(N)(=O)=O +CCN(CC)C(=O)COc1coc(CO)cc1=O +CC(C)C1(CNC(=O)c2ccc(-n3ccnn3)cc2)CC1 +CC(CO)NC(=O)c1cc2cc(Br)ccc2[nH]1 +Cn1cc(C(N)=O)cc1C(=O)OC(Cc1ccccc1)C(C)(C)C +O=C(CCc1ncc(-c2ccccc2)o1)Nc1n[nH]c(-c2ccco2)n1 +CCC(C)NC(=O)c1c[nH]nc1-c1ccc2c(c1)OCCO2 +CS(=O)(=O)c1ccc(F)c(NC(=O)c2c(F)cccc2Cl)c1 +CC(=O)Nc1ccccc1OCC(=O)N(C)c1ccccc1 +Cc1c(C(C)NC(=O)CCn2cncn2)cnn1-c1ccc(F)cc1 +CC(C)(C)c1n[nH]c(SCC(=O)NCCc2ccccc2)n1 +COc1cccc(-c2cc(CC(=O)NCc3cccs3)no2)c1 +CCC(C)CN(C)S(=O)(=O)c1cc(N)ccc1F +CCOC(=O)CCN1C(=O)C(C)Nc2cc(F)ccc21 +Cc1ccc(C(=O)N2CCN(CC(=O)N3CCCCC3)CC2)c(O)c1 +COc1ccc(-c2cnn(C)c(=O)c2C#N)c(OC)c1 +COc1cccc(C2CCN2C(=O)Cn2cccnc2=O)c1 +Cc1ccc(C)c(OC(C)C(=O)Nc2cc(N)ccc2F)c1 +CCCN(CCC)C(=O)Cn1cnc2sc(CC)cc2c1=O +Nc1cc(-c2ccc3c(c2)OCCO3)nc(N2CCOCC2)n1 +CS(=O)(=O)c1ccc2c(c1)CCCN2C(=O)COc1ccccc1 +CC(=O)N(C)c1ccc(NC(=O)NCC(C)(C)c2ccncc2)cc1 +O=C(c1cc(F)ccc1F)C1CCCN1C(=O)C1CC1 +Nc1nc2ccccc2nc1N1CCC(CO)CC1 +C#CCN(CC(=O)N(C)Cc1ccco1)Cc1ccc(F)cc1 +Cc1cc(C)c(CNC(=O)c2cc(-c3ccc(C)o3)n[nH]2)c(=O)[nH]1 +CC(C)c1ccsc1C(=O)N1CCN(C(=O)N(C)C)CC1 +COc1cc(OC)cc(C(=O)NCc2cccc(C)c2)c1 +CCNC(=O)COc1cccc(NC(=O)c2ccncc2CC)c1 +NC(=O)CNC(=O)c1ccccc1CSc1nc2ccccc2[nH]1 +CC(C)CC(C)N(C)C(=O)CN1CCN(c2nccs2)CC1 +CCN(C)C(=O)Cc1csc(-c2ccc(C)cc2)n1 +COc1ccccc1CNC(=O)c1cc(S(N)(=O)=O)oc1C +Cc1ccnc(OCC23COCC2CN(S(=O)(=O)C2CC2)C3)n1 +O=C(Nc1cccc(-c2cnco2)c1)c1ccccc1-n1cccn1 +Cc1ncc(CNc2ccc(C(=O)NCc3ccco3)cc2C)s1 +Cc1ccc(S(=O)(=O)Oc2cccc3cccnc23)c(F)c1 +CCC1C(=O)NCCN1C(=O)CCC(=O)Nc1c(C)cc(C)cc1C +COC(=O)c1cnn(-c2ccc(F)c(Cl)c2)c1N +CCc1nnc(NC(=O)c2cc(C)n(C3CC3)c2C)s1 +Cc1cc(C2CCCCN2C(=O)c2cnc(-c3cccnc3)nc2)no1 +COc1cc(C(=O)Nc2cc(C)on2)cc(OC)c1C +CC1CN(C2CCN(C(=O)CCc3cnn(C)c3)CC2)CC(C)O1 +Nc1c(F)cccc1C(=O)Nc1ccc(F)cc1F +CC(C(=O)Nc1ccc(Cl)cc1)N1CCn2c(nn(C)c2=O)C1 +COc1ccc(C(O)CNc2c(C)cccc2C)cc1OC +COCc1noc(-c2cccc(Oc3cnccn3)c2)n1 +CCC(NC(=O)NCCNC(C)=O)c1ccc(Br)cc1 +CCCOc1ncnc(NCc2ccccn2)c1N +COc1ccc(NC(=O)Cc2ccc(O)cc2)cc1Cl +O=C(CC1=Nc2ccccc2S(=O)(=O)N1)Nc1ccc(F)cc1 +CCSc1ccc(C(=O)OCCn2nc(C)cc2C)cn1 +c1csc(CNc2ncnc3c2oc2ccccc23)c1 +CCc1ncc(NC(=O)NC(C)C(O)c2ccc(OC)cc2)cn1 +COCCN(Cc1ccoc1)C(=O)Nc1c(F)cccc1F +Cc1nc(CNC(=O)c2c[nH]c3ccccc23)nc2c1CCCC2 +COC(=O)c1ccc(NC(=O)Cn2nnc(C(C)=O)c2C)cc1 +CC(C)(CNC(=O)CCNC(=O)c1cccs1)c1cccs1 +CC(=O)N1CCN(S(=O)(=O)c2cccc(F)c2C#N)CC1 +Nc1ncccc1-c1nc(-c2ccc(OC(F)F)cc2)no1 +COC(=O)c1ccc(C)c(NC(=O)COC(=O)c2ccoc2C)c1 +CC1Oc2c(N)cccc2N(CC(=O)N(C)C)C1=O +Cn1nccc1CNC(=O)C1CCCN(S(C)(=O)=O)C1 +O=C(Cc1cccs1)Nc1nnc(Cc2ccc3c(c2)OCO3)o1 +C=CCN(CC=C)C(=O)Cn1nnc2ccccc2c1=O +CCCc1nc(CN2CCN(C(=O)NCC)CC2)cs1 +CC(CC#N)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +Cc1ccc(-n2nc(N3CCOCC3)cc2N)cc1 +Cc1ccc(NC(=O)N(C)Cc2cnn(C)c2)cc1F +Nn1c(SCCOC2CCCCCC2)nnc1-c1ccccn1 +NC(=O)Cc1ccc(NS(=O)(=O)c2cc(F)ccc2F)cc1 +Cc1c(C(=O)OCC2CCCO2)[nH]c2c1C(=O)CC(c1ccco1)C2 +Cc1ccc(CNC(=O)c2ccnc(-c3ccsc3)c2)cc1 +COCc1ccc(C(=O)Nc2ccc(CC#N)cc2)cc1 +CC(C)C(=O)N1CCN(Cc2noc(-c3cccc(Cl)c3)n2)CC1 +CC(NC(=O)Cn1c(=O)oc2ccccc21)c1ccc(F)c(F)c1 +O=C(Nc1cccc(Cl)c1Cl)N1CCCC(CO)C1 +O=C(Nc1ccc2c(c1)OCO2)C1(c2ccccc2)CC1 +COCCN1C(=O)CCC12CCCN(c1ncc(F)cn1)CC2 +Cc1nn(C)cc1-c1ccnc(NCc2cc(F)c(F)cc2F)n1 +Cc1c(C(=O)NCCCC(N)=O)nnn1-c1cccc(Cl)c1 +Cc1noc(NC(=O)CCc2cc(F)ccc2F)n1 +Nc1ccc(Cl)c(C(O)c2ccc(Cl)cc2)c1 +c1ccc2[nH]c(C3CN(Cc4ccc(C5CCCO5)s4)C3)nc2c1 +CC1CN(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)CCO1 +COCCCNC(C#N)c1ccccc1C(F)(F)F +CC(=O)c1ccccc1NC(=O)CCCSc1cc(C#N)ccn1 +C=CCNC(=O)N(C)Cc1ccc(OC)c(OC(F)F)c1 +O=C(Cc1cccs1)NCc1ccc(Oc2ccccc2)nc1 +CC(C)c1nc2ccc(F)cc2n1Cc1cccnc1N +CCC(=O)NCC(=O)NC(C)c1ccc(Cl)c(Cl)c1 +CC(O)CNC(=O)c1cccc(OCc2nc(C3CC3)no2)c1 +Cn1c(SCC(=O)NCc2ccccc2)nnc1C1CCCCC1 +O=S(=O)(c1ccccc1)N1CCn2c(Cn3cccn3)cnc2C1 +CN(CCc1ccccc1F)C(=O)c1ccccc1N +CN(C)C(=O)CN1C(=O)C2CCC1CN(c1ncccc1F)C2 +O=C(NC1CC1)c1ccccc1NC(=O)C1CC=CC1 +O=C(Nc1ccc(NCc2nc(-c3ccccc3)no2)cc1)C1CC1 +NC(=O)C1CN(C(=O)Cc2cccc3ccccc23)c2ccccc2O1 +COc1cccc(C)c1NC(=O)NCCCC(C)(C)CO +CC(C)(C)NC(=O)COC(=O)COc1cccc2c1OC(C)(C)C2 +C=CCNC(=O)Nc1ccccc1NC(=O)c1ccsc1 +CC(c1ccccc1)S(=O)(=O)c1nc2ccccc2[nH]1 +O=C(NC1CCCc2occc21)C1(c2ccccc2)CC1 +O=C(CCn1c(=O)oc2ccccc21)NCCc1ccccc1F +COCc1cn(C2CCN(C(=O)c3cc(C)ccc3C)CC2)nn1 +C#CCOC(=O)CN1CCCc2sccc2C1=O +NC(=O)c1cc(S(=O)(=O)NC2CCCCCC2)cs1 +O=C1CC(c2ccccc2)N(C(=O)c2ccccc2O)CCN1 +CCNC(=O)C1CC(c2ccc(F)cc2)NS(=O)(=O)N1C +Cc1nc2ccccc2c(=O)n1-c1ccc(C(=O)Nc2nc[nH]n2)cc1 +Cn1nnnc1SCc1nnc(-c2ccccc2)o1 +Cc1cc(C(=O)Nc2ccc(-n3nncc3C(F)(F)F)cc2)ncn1 +O=C(Cc1noc(CCN2CCCC2=O)n1)NCc1ccccc1 +CCCS(=O)(=O)Nc1cccc(S(=O)(=O)N(C)C)c1 +CC(Sc1ccccn1)C(=O)Nc1ccc(Cl)cc1 +COCc1cc(Cn2cnc(-c3ccccc3)c2-c2cccnc2)n[nH]1 +Cc1cc(C)n2nc(SCc3ccc(F)c4cccnc34)nc2n1 +C#CCC(C)OC(=O)C1CCN(c2ccc(Cl)cn2)CC1 +O=C1CC(c2nc(-c3ccccc3)no2)CN1Cc1ccccc1 +CC1(C)CCCN1C(=O)c1csc(-c2ccsc2)n1 +CCC(C)n1ncc(C(=O)Nc2ncc(C(N)=O)s2)c1C1CC1 +O=C(CCCC(O)c1ccc(F)c(F)c1)N1CCOCC1 +CCNC(=O)c1ccc(CNC(=O)COc2ccccc2Cl)cc1 +CC(C1CC1)N(C(=O)Cn1ncc2ccccc2c1=O)C1CC1 +Fc1ccccc1-n1cc(NCc2cc[nH]n2)cn1 +COCCn1c(C(C)O)nc2cc(C(F)(F)F)ccc21 +CS(=O)(=O)NCCC(=O)N1CCCC1c1ccsc1 +CCOC1CC1C(=O)N1CC(CCN2CCCC2=O)c2ccccc21 +CC1CC(=O)Nc2cc(Br)cc(Cl)c2O1 +COc1ccc(C(=O)Nc2ccc(Cl)cc2C)cc1N +Cc1ccncc1NC(=O)N1CCN(CC(F)(F)C(F)F)CC1 +CCOC(=O)c1cc(C(=O)Nc2ccccc2CC)c(=O)[nH]c1C +CCC(O)CN1CCN(C(=O)c2nn(C)c(=O)c3ccccc23)CC1 +CC(C)OCc1cccc(NC(=O)C2CC(=O)N(C3CCCC3)C2)c1 +O=C(c1ccc(Br)cc1F)N1CCCCC1CCO +CCCCC(=O)Nc1ccc2c(c1)nc1n2CCN(C)C1 +O=C1CN(C(=O)Nc2cccc(Br)c2)CCN1 +COc1cc(C(=O)N(C)CCO)cc(N)c1OC +C=CCN(Cc1ccc(-n2cncn2)c(C)c1)CC(F)(F)F +Cc1ccc(SCCC(=O)NC(C)c2ccncc2)cc1C +COc1ccccc1-n1c(C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 +Cc1nnc(SC(C(=O)Nc2ccc3c(c2)CCC3)C(C)C)s1 +CCCC(=O)Nc1sc2c(c1C(=O)NC)CCC(C)C2 +OCCc1nnc(-c2ccc3nc(C4CC4)[nH]c3c2)o1 +CCOC(=O)N1CCN(CC(=O)NC2(c3ccccc3)CCC2)CC1 +COc1cc2ncnc(NCc3ccccc3F)c2cc1OC +COc1cn(-c2ccccc2)nc1C(=O)OC(C)C#N +OCc1nnn(-c2cccc(F)c2)c1Cc1ccc(F)cc1 +COC(=O)Cn1c(-c2cccc(N)c2)nc2cc(N)ccc21 +O=C(NCc1ccncc1)NCc1cccc(OCc2ccccc2)c1 +COc1cc(C)sc1C(=O)NC1CCN(c2ccccc2)C1=O +CCn1cc(C(=O)Nc2ccccc2)c(=O)c2ccc(C)nc21 +CCc1nnc(CN2CCCC2c2nc3ccccc3s2)o1 +CCc1cc(C(=O)N2CCC(Cc3ccc(CO)cc3)C2)cs1 +CCc1cccc(OCCCN(C)c2ncnc3oc(C)nc23)c1 +COCC(C)(O)CNC(=O)C1(c2cccs2)CCCC1 +Cc1cc(C)n2c(SCc3ncc(-c4ccccc4)o3)nnc2n1 +COC(=O)CSc1nnc(-c2cccnc2)n1-c1ccccc1C +CC(NC(=O)C(C)(C)C)C(=O)OCC1CCCO1 +Cc1cc(C(=O)Nc2ccc3scnc3c2)nn1C +CC(C)(C)CN(CCC#N)CC(=O)N1CCOCC1 +CCOc1ccccc1-n1nnc(C(=O)Nc2ccccc2F)c1C +CSc1c(C(O)CO)sc2nc3nc(N)[nH]c(=O)c3nc12 +COCC(=O)N1CC2COCC(CC(=O)N3CCCC3)C2C1 +CC(=O)NC1CCN(C(=O)c2cc(C)nc3c(C)cccc23)CC1 +O=C(NC1(c2ccc(Cl)c(Cl)c2)CC1)c1cccnc1 +Cc1cc(CNC(=O)c2cc3ccccc3oc2=O)nn1C +COc1ccc(OC2COCCN(C(=O)c3cc(C)nn3C)C2)cc1 +N#Cc1nccc2c(Br)cc(F)cc12 +COc1cc2nc(C)sc2cc1NC(=O)NCCO +CCc1noc(C)c1C(=O)OCC(=O)Nc1cccc(Cl)c1 +O=C(NCc1ccnc(OC2CCC2)c1)C1CC1c1ccccc1F +Cc1ccc(OCC(=O)NCc2ccsc2)cc1 +O=C1CSc2ccc(C(=O)C3CCCC3)cc2N1 +CCC(C)c1noc(C2CCCCN2C(=O)Cn2nc(C)cc2C)n1 +CC1(C)CCC(CNC(=O)c2cccc(C(=O)N3CCCC3)n2)CC1 +CN(C)C(=O)Sc1ccccc1NC(=O)c1ccoc1 +OCc1ccc(CN2CCCC(c3ccccc3)C2)o1 +CC(CO)C(C)NC(=O)Nc1ccccc1N(C)Cc1ccccc1 +Nc1oc2c(c1C(=O)c1ccc(C(F)(F)F)cc1)CCC2 +COc1ccc(Cl)cc1CC(=O)Nc1ccc(C#N)cc1 +O=C(NCCc1ccsc1)c1cnc2ccccc2n1 +CS(=O)(=O)c1cccc(NC(=O)c2cc(=O)[nH]c3ccccc23)c1 +CSc1ncc(CNC(=O)C2CC(=O)N(C(C)(C)C)C2)n1C +CC(C)(C)c1ccc(S(=O)(=O)NCCn2ncccc2=O)cc1 +COc1ccnc(N2CCCC2C(=O)NCC(F)(F)F)n1 +Cc1cnnn1-c1ccc(C(=O)Nc2ccccc2)cc1 +COc1ccc(F)cc1C(O)CCNc1cccc(F)c1 +Cc1cc(F)cc(C(=O)N(CCO)CCN2CCOCC2)c1 +C#CCCNS(=O)(=O)c1cccc(Cl)c1C +Cn1nnnc1SCC(=O)Nc1ccc(S(N)(=O)=O)cc1 +COc1ccc(C(=O)N2CCC(O)(c3cccnc3)CC2)cc1OC +Cc1csc(CNc2ccc(C(=O)NC3CCCC3)cc2C)n1 +CC(C(=O)N(C)Cc1n[nH]c2c1CCCC2)n1ccnc1 +CC(C)N1CC(C(=O)NCc2cccnc2-n2cccn2)CC1=O +CCOc1cc(C#N)ccc1OCC(=O)c1ccc(NC(C)=O)cc1 +CCc1nc2n(n1)CC(Nc1ncnc3sccc13)CC2 +C=CCOC1CCN(C2CCOC2)C1Cc1cccnc1 +Cc1ccc(C(NC(=O)c2cnccn2)c2ccccc2)cc1 +NC(=O)c1cccnc1N1CCC2(CC1)Nc1ccccc1NC2=O +Cn1cc(NC(=O)C2CCN(C(=O)CCC3CCCC3)C2)cn1 +Cc1ccc(NC(=O)NCCN2CCOCC2)cc1OCC(F)F +CC(=O)c1cccc(OC(C)C(=O)N(C)CC(O)C2CC2)c1 +Cc1noc(CNC(=O)N(Cc2ccccc2)CC(C)(C)O)n1 +CNc1nc(C(N)=O)c(NC(=O)c2ccc(OC)c(OC)c2)s1 +COc1ccc(C2NC(=O)c3ccccc3O2)c(OC)c1OC +CC(C)c1n[nH]c(C2CN(C(=O)OCc3ccccc3)CCO2)n1 +Cn1nc2c(Br)cccc2c1CCO +O=C(c1cccc(F)c1)N1CCC(c2nnc3n2CCCCC3)CC1 +CCn1cc(CN(C)C(=O)c2ccnn2CC)cn1 +CN(C)c1ccc(C(=O)N2CCN(Cc3ccsc3)CC2)cc1 +COc1ccc(C(=O)OCc2nc(-c3cccc(F)c3)no2)cn1 +CCCCC(=O)NCc1nnc(C(=O)Nc2cccc(F)c2)s1 +CCCCn1nc(C(=O)Nc2nncs2)ccc1=O +COC(=O)c1ccc(CN2C(=O)c3ccccc3S2(=O)=O)cc1 +Cc1ccc(NC(=O)c2ccc(-c3cscn3)cc2)cc1C(N)=O +O=C(NCc1cc[nH]n1)N1CCN(Cc2ccc3c(c2)CCO3)CC1 +CCC(C)Oc1cc(C(=O)Nc2cc(C)nn2C)ccn1 +NS(=O)(=O)c1cnc(NC2CCc3ccccc32)s1 +CCN(Cc1ccccn1)C(=O)CNC(=O)c1c(F)cccc1Cl +C#CCN1CCN(C(C)C(=O)N2CCN(c3ccccc3)CC2)CC1 +CCSc1ccccc1C(=O)Nc1nnc(-c2cc(C)oc2C)o1 +CCC(CC)N(C)C(=O)c1cnc2sccn2c1=O +COC(=O)c1cccc(S(=O)(=O)NC2CCCCC2)c1 +CC(C)(C)OC(=O)N1CCCC(C(=O)NCCc2ccccn2)C1 +N#Cc1ccccc1NC(=O)Cc1ccc(F)cc1F +CCNS(=O)(=O)c1cc(C(=O)NCc2cccnc2)ccc1OC +CC1Cn2c(nc3c(Cl)cc(Cl)cc3c2=O)S1 +Cc1ccc(CNC(=O)c2ccc(C)nc2)c(OCC2CC2)c1 +O=C1NCCNc2c1cnc1ccc(Br)cc21 +COc1ccc(C(=O)n2nc(C)c(C)c2C)c(OC)c1OC +CCOC1CC(Nc2ncccc2-c2nc(C)no2)C12CCC2 +CCC(C(N)=O)N(c1cc(Cl)ccc1C)S(C)(=O)=O +Cc1cc(NC(=O)c2ccc(Br)cc2-n2cncn2)[nH]n1 +O=C(Nc1nc2c(s1)COCC2)c1ccc2[nH]cnc2c1 +Cc1noc(NC(=O)C2CCCN(C(=O)c3cccs3)C2)n1 +O=C(CC1Oc2ccccc2NC1=O)NCCCN1CCOCC1 +c1nc(N2CCC(c3nnc4n3CCC4)CC2)c2ccsc2n1 +Cc1ccc(N2CCN(C(=O)C(C)C)C(C)C2=O)cc1Cl +O=C(CC1OCCc2ccccc21)NCC(O)C1CCCCC1 +COc1ccc(OCC(=O)Nc2ccc(-n3ccnc3C)nc2)cc1 +COc1ccc(C(O)CCCC(=O)N2CCCC2)c(OC)c1 +CCOC(=O)C(C)NC(=O)c1ccc(=O)n(C)c1 +NC(=O)c1ccc(C(=O)N(Cc2nccn2C(F)F)C2CC2)cc1 +O=C(CNC(=O)c1cc2ccccc2oc1=O)c1ccccc1 +Cc1ccccc1CNc1ccccc1C(=O)N1CCOCC1 +CCOC(=O)c1ccsc1NC(=O)N(C)CCC(C)O +CCS(=O)(=O)N1CC2CN(C(=O)c3cnccn3)CC2C1 +Cc1nc(CN(C)C(=O)C(NC(N)=O)C(C)C)cs1 +CCc1cccc(C)c1NC(=O)C(NC(C)=O)C(C)C +CCOc1ccc(F)c(C(=O)NC2CCN(C(C)C)C2=O)c1F +COCCNC(=O)NCCCn1nc2n(c1=O)CCCC2 +COc1ccc(OC)c(NC(=O)c2ccc(F)c(F)c2F)c1 +O=C(NCc1cccs1)c1ccc(=O)n(Cc2ccccc2)n1 +Cc1cc(NC(=O)c2cccc(F)c2F)n(Cc2ccccc2)n1 +O=C(Nc1nc(-c2ccco2)n[nH]1)c1ccc2c(c1)CCCC2 +O=C(Nc1ccc2c(c1)OCCCO2)c1ccc(O)cc1 +CCN(CC)C(=O)C(C)n1c(N)nnc1SC +CCN1CCN(C(=O)c2cc3cc(C)ccc3[nH]2)CC1 +CCCn1cc(CN2CCN3C(=O)CNC(=O)C3C2)c(C)n1 +CN(C)C(=O)Cc1ccccc1NCc1cc(C#N)cs1 +Cc1ccc(-c2cc(=O)n(CC(=O)NC(C)C)cn2)cc1 +Cc1ccn2c(=NC(=O)c3cnn(C)c3)[nH]nc2c1 +CCC(=O)Oc1cccc(C(=O)Nc2cc(OC)ccc2OC)c1 +CCn1c(SC(C)c2nc3ccccc3s2)nnc1C1CC1 +CCOc1ccc(NC(=O)CN2C(=O)COc3ccc(C)cc32)cc1 +CSc1ccc(C(=O)Nc2ccc(C(=O)NCC(N)=O)cc2)o1 +CNC(=O)c1cccc(CSc2ccccc2O)c1 +Cc1ccc(NC(=O)c2nc(N3CCCC3)ncc2Cl)nc1 +CCc1cnc(CNc2cccc(C(=O)N3CCC(CO)CC3)c2)o1 +CC(Cc1ccncc1)Nc1cc(N2CCCCC2)ncn1 +CCc1cc2c(N3CCCC3c3noc(C)n3)ncnc2s1 +CC1(COC(=O)c2ccc(N3CCOCC3)cc2)COC1 +c1ccc2c(c1)CCC21CN(Cc2cccc3c2OCO3)CCO1 +Cc1nn2cccnc2c1C(=O)OCc1nc2ccccc2s1 +Cc1nn(C)c(C)c1CNC(=O)c1ccc2c(ccn2C)c1 +Cc1ccc(F)c(OCC(=O)Nc2nccs2)c1 +O=C1NC2(Nc3ccc(Cl)cc31)C(=O)Nc1ccccc12 +Cc1sc(C(N)=O)cc1S(=O)(=O)Nc1ccccc1 +CC(C)(CO)C1NCCc2c1cc(F)cc2C(F)(F)F +CCc1c(C(=O)N2CC(C)OC(C)C2)cnn1-c1ccc(OC)nn1 +Cc1ccc(CNC2OC(=O)c3ccccc32)cc1 +O=C(Cn1c(-c2cccs2)noc1=O)NC1CCCCCC1 +c1ccc(COc2ccc(CN3CCOCC3)c3cccnc23)nc1 +CNC(=O)c1cccc(CNC(=O)CN(C)C(C)=O)c1 +CC1CN(C)CCN1C(=O)c1ccnc(Oc2ccccc2)c1 +N#Cc1ccc(CNC(=O)NCCc2cccc(C(N)=O)c2)cc1 +CCS(=O)(=O)NC1CCN(c2nccc(OC)n2)CC1 +Cc1cc(C(=O)NCC(C(C)C)N2CCOCC2)on1 +c1ccc(-c2nnnn2C2(n3cccn3)CCCCC2)cc1 +CCc1nc(CSc2ncnc3sc(C)cc23)cs1 +C#CCN1C(=O)CSc2nnc(COc3ccc(Cl)cc3)n21 +COc1cc(CNc2cccc(C)c2C)cc(OC)c1O +O=C(CCCn1cncn1)Nc1ccc(OC2CCCC2)c(Cl)c1 +Cc1c(C(=O)NC2(C#N)CC2)cnn1-c1ccncc1 +Cc1cc(CN(C)C(=O)CCC(=O)N2CCOCC2)no1 +OC1CCN(c2nc(-c3ccncc3)nc3c2CCC3)CC1 +Cc1ccc(-n2cc(C(=O)N3CCNC(=O)C3)nn2)cc1 +Cc1cc(C)cc(NC(=O)CNc2cc(Cl)ccc2C(N)=O)c1 +O=C(c1cc2cc(Cl)cc(Cl)c2oc1=O)N1CCCC1 +CC(Sc1nnc2ccccn12)C(=O)c1c[nH]c2ccccc12 +Cc1cc(C(C)Nc2ccc(N)cc2F)c(C)s1 +CC(=O)c1cccc(NC(=O)NC(C)C(=O)Nc2ccccc2)c1 +CC(=O)N(CCc1ccccc1)CC(=O)N1CCNC(=O)C1C(C)C +CCOCCCNC(=O)c1nnn(-c2ccc3ncccc3c2)c1C +CN(C)c1cc(C(=O)N2CCC3OCCCC3C2)ccn1 +CCC(C)OC(=O)c1cccnc1OCC(F)F +O=C(c1ccco1)N1CCc2c(cnn2-c2ccccc2)C1 +CC1Sc2ccc(C(=O)NC(C)c3ccccc3)cc2NC1=O +COCCNC(=O)NCCc1nc2cccnc2n1C1CCCCC1 +CC(=O)NC(C)(C)c1noc(CCCOc2ccc(F)cc2F)n1 +CCCCOC(=O)Cn1cc(C(=O)NC)ccc1=O +CCN(CCC(=O)OC)C(=O)c1n[nH]c(=O)c2ccccc12 +CCCn1cc(NC(=O)c2cccnc2OCC(F)F)cn1 +CNc1ncc(Br)cc1C(=O)N(C)CCC(C)C +CCc1noc(COc2cccc(NC(=O)CN3CCCC3=O)c2)n1 +COCc1nc(-n2ccnc2)c2c(-c3ccccc3)csc2n1 +CC(=O)c1ccccc1NC(=O)c1cnn(-c2ccccn2)c1C +COc1ccc(-n2nnc(C(=O)Nc3nccs3)n2)cc1 +CCc1noc(CN(C)C(=O)C2CC3CCC2O3)n1 +Cc1ccccc1-n1nc(CO)c(C(=O)NCc2ccccc2)n1 +CCOC(=O)c1ccc(NC(=O)C(OC)c2ccccc2)cc1 +O=C(NCCc1ccccn1)C1COC(=O)N1Cc1cccc(O)c1 +COC(=O)C1CC2CCCCC2N1C(=O)c1cnns1 +Cc1ccc(C(=O)CCC(=O)NC(C2CC2)C2CC2)cc1 +CCn1ccnc1CN1CCCN(C(=O)c2ccsc2)CC1 +CCNc1nc2c([nH]1)c(=O)n(CC)c(=O)n2CC(C)C +N#Cc1ccsc1NCc1cc(F)ccc1F +Cc1ccc2c(CC(=O)NC(C)c3ccccn3)coc2c1 +CCS(=O)(=O)c1ccccc1NC(=O)C1CC=CCC1 +Cc1nc(Cc2noc(C3(c4ccccc4)CCC3)n2)no1 +O=C(CNC(=O)Cc1cccc2ccccc12)NCc1ccncc1 +COC1CCCN(C(=O)Nc2ccc(C(C)=O)c(C)c2)C1 +Cc1nc(C2CCN(C(=O)Cn3cc(Cl)c(C)n3)CC2)cc(=O)[nH]1 +Cc1cc(NC(=O)c2ccco2)sc1C(=O)NC(C)C(N)=O +CN(CC(=O)c1cccs1)C1CCN(C(=O)OC(C)(C)C)CC1 +Cc1nc(-c2c(-c3ccccc3)ncn2CCOc2ccccc2)c[nH]1 +C=CCOC(C)C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1cc(-c2nn3c(-c4ccccn4)nnc3s2)[nH]n1 +CC(C)(C)OC(=O)N(CCNC(=O)c1ccc(F)nc1)C1CC1 +CCn1nc(NCc2cc(F)cc(F)c2)cc1C +CCC(=O)Nc1cnc(NC(=O)c2ccco2)cc1C +CSc1ccccc1-n1c(Cn2nc(C)c(C)c2C)n[nH]c1=O +Cc1ccccc1N1C(O)=Nc2ccccc2S1(=O)=O +CCn1cc(C(=O)NC(C)c2nc3ccccc3o2)c(C)n1 +Cc1ccc(C(=O)C(C)OC(=O)Cn2c(C)csc2=O)cc1 +Cc1ccc(OCc2cccc(C#N)c2)c(CO)c1 +CCn1nc(C)cc1C(=O)N(CCC(N)=O)Cc1ccccc1 +C=Cc1ccc(Cn2cnc3c(cnn3-c3ccc(F)cc3)c2=O)cc1 +COC(=O)c1cc2n(n1)CCN(Cc1ccc(OC)cc1)C2=O +Cc1ccc(C)c(C(=O)C2CCN(S(C)(=O)=O)CC2)c1 +CC(O)Cn1c(CO)cc(=O)c(O)c1CN1CCOCC1 +CC(C)Oc1ccc(-c2nc3ccc(N)cn3c2CC#N)cc1 +O=C(OCc1nncn1C1CC1)c1ccc(Oc2cccnc2)cc1 +O=C(NCCN1CCOCC1)c1nnc(Cc2cccc(F)c2)o1 +CC(=O)Nc1ccc(NC(=O)Nc2ccc(C)cc2)cc1 +CC(=O)c1c(C)[nH]c(C(=O)Cn2nnnc2C(C)(C)C)c1C +Cc1nnc(NC(=O)CC2NC(=O)c3ccccc3N=C2O)s1 +Cc1n[nH]c(-c2ccc(NC(=O)c3ncoc3C(C)C)cc2)n1 +COC(=O)c1cc(CNC(=O)c2cccn2C)oc1C +CCN1CCN(C(=O)C23CCC(C2)C(C)(C)C3=O)CC1 +CCn1ccc2c(CCC(=O)NCC3CCCO3)cccc21 +COc1ccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3)cc1OC +Cc1nc(-c2ncccn2)sc1C(=O)Nc1cccnc1 +NC(=O)C1(NC(=O)CSc2ccncc2)CCCCC1 +O=C(Nc1ccccc1C(=O)N1CCCC1)c1ccccc1Cl +O=C(NCCCOc1ccccc1)c1c(O)cccc1O +COC(=O)C1CC(O)CCN1Cc1cc(C)ccc1-n1cccn1 +C#CCN1CCN(C(=O)c2ccc(-n3ccnn3)cc2)CC1 +CC(C)C(=O)NC(C)c1cccc(N2CCCC2=O)c1 +N#Cc1cccc(C(=O)NCCOc2cccc3cccnc23)c1 +NC(=O)C1CCN(C(=O)CCCN2Cc3ccccc3C2=O)CC1 +COc1ccccc1CNC(=O)Cn1nnc(-c2ccccc2C)n1 +COc1ccc(C(C)N(C)C(=O)NCc2ccc(OC)nc2)cc1 +Cc1cc(C(=O)NCC(=O)NC2CCCCCC2)n(C)n1 +CS(=O)(=O)N1CCCN(C(=O)c2ccc(O)c(Cl)c2)CC1 +COC(CNC(=O)c1ccccn1)c1cccc(F)c1 +NC(=O)c1n[nH]c2ccc(NC(=O)CCc3ccc(Cl)cc3)cc12 +CC(C)N(CC(N)=O)C(=O)Cc1coc2cc3c(cc12)CCC3 +CCN(CCC(=O)OC)C(=O)c1ccc(C(C)C)cc1 +CCOC(=O)C(CC)N1C(=O)CNc2cc(C)c(C)cc21 +CCCS(=O)(=O)N1CCC2(CCCC(=O)N2C)CC1 +CCCNC(=O)CCC(O)c1ccc(Br)cc1 +O=C(Cc1ccc(F)c(F)c1)NCC(=O)Nc1ccccc1 +O=C(Nc1cccn(Cc2ccc(F)cc2)c1=O)N1CCCC1 +Cc1cc(C)n(CCC(=O)Nc2ccc(F)cc2C)n1 +Cc1csc(NC(=O)COC(=O)c2cccc(Cl)c2Cl)n1 +CNC(=O)c1ccc(C2CCCN(S(C)(=O)=O)C2)nc1 +N#Cc1ncn(Cc2ncc(-c3ccccc3)o2)n1 +CCC1CCCN(C(=O)c2ccc(-n3cncn3)cc2)C1 +CS(=O)(=O)NCCn1c(=O)[nH]c2ccccc2c1=O +Cc1ccc(C2(O)CCN(C(=O)c3cc4sccc4[nH]3)CC2)nc1 +CC(C)NC(=O)CC(C)Nc1cc(C(F)(F)F)ccn1 +CCn1nc(C)c(C(=O)Nc2cc(C)c(C)c(C(=O)OC)c2)c1C +NC(=O)C1(CNC(=O)c2ccc3cc[nH]c3c2)CCOCC1 +CCCn1nc(C(=O)Nc2cccc(C(=O)OC)c2)ccc1=O +COCc1nn(CC2CC2)c2c1CN(c1ccc(C)nn1)CC2 +COc1cccc(C2NCCc3c(O)cc(O)cc32)n1 +CN(C)S(=O)(=O)CCNC(=O)C1CC1c1ccccc1 +CC(C(=O)N1CCN(c2ccccc2F)CC1)n1cccn1 +Cc1nc(-c2nnn(Cc3cccc(F)c3)c2C)no1 +O=C(Nc1ccc(F)cc1Cl)c1cnn(-c2ccc(F)cc2)n1 +CCCCN(CC)C(=O)NCc1ccc(N2CCCCC2=O)cc1 +COC(=O)CC1C(=O)NCCN1C(=O)CCc1c[nH]c2ccccc12 +Cc1cc(CNC(=O)C(C)(C)NC(=O)Nc2ccccc2)no1 +Nc1cccc(OCC(=O)OCC2CCCO2)c1 +Cc1cc(C)c(NC(=O)c2ccc(Cl)cc2)c(C)n1 +Cn1c(C(=O)c2ccccc2)nc2cc(O)ccc21 +Cc1cc(Br)cc(C)c1OCC(=O)NCc1cccnc1 +O=C(CNC(=O)NCc1ccc2c(c1)OCCO2)NC1CCCCC1 +CCOc1cccc2c(=O)ccn(CCC(N)=O)c12 +Nc1c(Br)cccc1-c1nnc2ccccn12 +Cc1ccc(CNc2ccccc2CCO)cc1F +CCCCN(CC)C(=O)C1CSc2nc(C)c(CC)c(=O)n2C1 +CCCn1cc(C(=O)NC(C)C(O)c2ccccc2)c(C)n1 +COc1ccc(CCNC(=O)Cc2ccc(-n3cccc3)cc2)cc1 +Cc1ccc(-n2ccnc2)c(C(=O)N(C)Cc2ccc(C)s2)c1 +CC1(NC(=O)Cc2ccc3c(c2)OCCO3)Cc2ccccc2C1 +COc1cccn(CC2Cc3c(C)nc(C)nc3O2)c1=O +C=CCNc1cccc2c1CCN(S(C)(=O)=O)C2 +Cc1ncc(CNc2cnn(-c3ncccn3)c2)n1-c1ccccc1 +COC(=O)Nc1nc2c(s1)CN(CC(N)=O)CC2 +COC(=O)N(C)c1ccc(NC(=O)NCc2cccc(Cl)c2)cc1 +CC(C)CC(=O)NCCc1nc(-c2ccccc2)n[nH]1 +Nc1cccc(NC(=O)NCCc2ccsc2)c1 +Cc1csc(Sc2c(N)cccc2Cl)n1 +CN(C)C(=O)c1c[nH]nc1C1CCCN1CCc1ccccc1 +CCOc1cc(C(=O)Nc2c(C)nn(CC)c2C)cc2occc12 +O=C(CSc1nnc(N2CCCC2)n1C1CC1)c1ccc(F)cc1 +CCSc1ccc(C(O)Cn2cc(N)cn2)cc1 +CCOc1ccc(CN(C)C(=O)c2cc3ccccc3oc2=O)cc1 +NC(=O)C1CCN(C(=O)c2nccc3c(N)cc(F)cc23)CC1 +COc1ccc(NC(=O)C(C)OCCC(C)C)c(N)c1 +O=C1CCC(C(=O)Nc2cccc(OCc3ccc(F)cc3)c2)N1 +Cc1nn(CC(=O)NC(C)CN2CCOCC2)cc1Cl +O=C(CCn1cccn1)NCc1ccnc(OC2CCC2)c1 +COC(=O)C1=C(C)N(C)C(=O)NC1c1ccccc1C +CC(NC(=O)Nc1cnn(C)c1)c1ccc(C#N)cc1 +O=C(Cc1ccc(F)cc1F)N(Cc1ccco1)Cc1ccco1 +N#Cc1cccc(C(=O)Nc2cccc(N3CCCS3(=O)=O)c2)c1 +O=C(Nc1ccnn1CC1CC1)C1COc2ccc(F)cc2C1 +Cc1ccnc2nc(C(=O)NC(C)c3cccc(Cl)c3)nn12 +COc1cc2c(cc1OC)CN(C(C)c1ccncc1)CC2 +O=C(NCCc1nc[nH]n1)Nc1ccccc1SC1CCCC1 +Cc1cccc(C(C#N)NCc2ccccc2F)c1 +O=C(c1ccc2c(c1)CCO2)N(Cc1ccncc1)Cc1cccnc1 +CC(NC(=O)NCc1cccnc1)C(=O)N1CCc2ccccc21 +Cc1ccc(C(=O)N2CCN(c3ncnc4[nH]cnc34)CC2)cc1 +Cc1cnn(CC2CCCCN2C(=O)CCCn2cncn2)c1 +CCN(C(=O)COc1ccc2ccc(=O)oc2c1)c1ccccc1 +Cc1sc(C(N)=O)cc1S(=O)(=O)NC1CCCCCC1 +Cc1nn(C)c2ncc(C(=O)N3CCCC3)c(NCc3ccccc3)c12 +Cc1ccc(NC(=O)C2CCCC2)cc1NC(=O)c1ccncc1 +CSc1nc2nnc(C(=O)Nc3ccc(C)c(Cl)c3)c(C)n2n1 +O=C(c1ccco1)N1CC=C(c2ccccc2)CC1 +CCOC(=O)CCN(C(=O)c1ccc(=O)n(C)n1)C1CC1 +CC(C)(CNC(=O)c1cn2cccnc2n1)N1CCOCC1 +COC(=O)c1ccc(CN(C)S(=O)(=O)c2cnn(C)c2)cc1 +NC(=O)CNC(=O)c1cccc(NC(=O)CCC2CCCC2)c1 +Cc1ccc(-c2nnc(COc3ccc(-c4nnco4)cc3)o2)cc1 +CCc1ccccc1OCc1nc(CC)c(CO)s1 +CCC(C)NC(=O)CCC(O)c1cc(C)ccc1C +COc1cccc(CN2CCC(c3nnc(-c4ccco4)o3)C2)c1 +COCc1nc2cc(C(F)(F)F)ccc2n1C(C)C +COc1ccc2c(c1)nc(C(C)C)n2Cc1cccnc1N +COc1cc(C)ccc1NC(=O)N(C)Cc1cscn1 +CN(CC(=O)N(Cc1cnc2ccccn12)C1CC1)S(C)(=O)=O +Cn1c(=O)c(=O)n(C)c2cc(NC(=O)c3ccc(Cl)cc3)ccc21 +O=C(Cc1noc(C2(c3ccccc3)CC2)n1)NCc1ccccc1 +CC(C)c1cc(C(=O)NC(C)c2cnn(-c3ccccc3F)c2)no1 +Cc1cc(NC(=O)CCc2ccc(S(=O)(=O)NC3CC3)cc2)no1 +COc1cc2ncnc(NCc3cccnc3)c2cc1OC +NC(=O)C1CCN(C(=O)CCn2cnc3sccc3c2=O)CC1 +CCCCNc1nnc(-c2cc3c([nH]c2=O)CCC3)s1 +CC(O)c1c(F)cccc1Oc1ccc(F)cc1 +Cc1ccn(C)c(=O)c1NC(=O)Cc1cccc(OCC#N)c1 +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)OCc1ccccc1 +CSc1ccc(C(=O)N2CCOCC2C)cc1 +NC(=O)c1ccc(COc2ccc(N3CCCC3=O)cc2)cc1 +Cc1cccc(C(=O)N2CCN(Cc3ccc(C(C)C)cc3)CC2)n1 +N#CC1(C#N)C(C(=O)C23CC4CC(CC(C4)C2)C3)C12CCOCC2 +CCN(CCNC(=O)Nc1cccnc1)c1ccccc1C +O=C(NCCCn1nnc2ccccc21)c1cccc(-c2ncc[nH]2)c1 +CCOC(=O)C(C)Sc1nnc(-c2ccco2)c(-c2ccco2)n1 +COc1cccc(CC(=O)OCC(=O)NC2(C#N)CCCC2)c1 +N#Cc1cccc(NS(=O)(=O)c2ccc(Cl)cc2N)c1 +Cc1c(C)n(Cc2cccnc2)c2ncnc(NCc3cccnc3)c12 +Cc1cc(F)ccc1CCNC(=O)Nc1ncn(CC(=O)N(C)C)n1 +CCn1cnnc1CNC(=O)C1CC(=O)N(Cc2ccccc2)C1 +Cc1cc(C)n(CC2CCCN2C(=O)c2ccn(C)c(=O)c2)n1 +O=C(NCc1nc2ccccc2s1)c1cc(=O)[nH]c2ccccc12 +COC(=O)CN(CCn1cncn1)C1CCCC1 +CCOc1ccc(C2=CCN(C(=O)COCC3CCCO3)CC2)cc1 +COC(=O)NCCC(=O)N1CCc2ccc(Cl)cc2C1 +Cc1ccc(NC(=O)C2CCN(C(=O)C3CC3)CC2)cc1C +Cc1c(N)cc(C(=O)N2CCCC(O)C2)cc1F +CCOc1cc(CNC(=O)c2cc3ccccc3s2)ccn1 +Cc1cccc(NC(=O)C2COCC(=O)N2Cc2ccccc2)n1 +O=C(Cc1cnccn1)N1CCC2(CCCN(CC3CC3)C2=O)C1 +COC(=O)Nc1cccc(NC(=O)c2c(C)cc(C)[nH]c2=O)c1 +CC1CC(C)CN(C(=O)Nc2ccc(F)c(C(N)=O)c2)C1 +CN(C(=O)CN1CCN(c2ccccc2F)CC1)C1CCCCC1 +CC(CNC(=O)c1cccc(Br)c1)CN1CCCC1=O +Cc1nc(C)c(COC(=O)CC(C)NC(=O)C2CCCC2)s1 +CC(CNC(=O)C(C)(C)c1ccccc1)Cn1cccn1 +c1ccc2ncc(C3NCCc4ccc5[nH]ccc5c43)cc2c1 +CCOCCNC(=O)N(C)C(C)c1ccccc1 +CCCn1cnnc1C(C)Nc1nc(N)ncc1C +CN(Cc1nc2ccccc2[nH]1)C(=O)C1CCCCC1 +CC(=O)Nc1nc(C(=O)NC(c2ccccc2)C2CC2)cs1 +COc1cccc(OCC(=O)N(C)Cc2ccc(F)c(F)c2)c1 +CCn1cc(C(=O)Nc2ccc(Br)cc2)c2cccnc21 +CCOC(=O)Cn1nc(C#N)cc1-c1cccc(Cl)c1 +Cc1ccc(NS(=O)(=O)c2cn(C)nc2N)cc1 +Cc1nc(-c2ccncc2)[nH]c(=O)c1CC(=O)N(C)C1(C#N)CCC1 +Cc1nc(-c2ccc(NC(=O)c3ccc(F)cc3)cc2)no1 +CCc1noc(CC)c1CNC(=O)Nc1ccncc1 +CCOC(=O)CCC(C)NC(=O)c1cc2ccccc2n1C +O=C1NCCCCC1Sc1nc(Cc2cccs2)n[nH]1 +CCc1ccccc1OCC(=O)Oc1ccc(C#N)cc1OC +Cc1c(C(=O)Oc2ccc3c(c2)OCO3)cnn1-c1ccccc1 +COC(=O)CC1C(=O)NCCN1C(=O)Nc1ccc(Cl)cc1 +CCOC1CCCN(C(=O)c2cccnc2Oc2cccnc2)C1 +COc1ccc(C(=O)NCC(=O)NC(C)C)cc1OC +COc1ccc(OC)c(NC(=O)NCc2ccc(OC)c(F)c2)c1 +CC(C)CC(=O)Nc1ccc(NC(=O)c2ccc[nH]c2=O)cc1 +COCCOc1ncccc1C(=O)Nc1cc(C#N)cn1C(C)(C)C +Cc1ncsc1-c1nc(Cn2cnc3cc(F)ccc3c2=O)no1 +CSc1cccc(NC(=O)CCn2cccn2)c1 +CC(=O)NC(C(=O)Nc1nc(C)c(C)s1)C1CCCC1 +COCCn1cc(Nc2nc3ccccc3s2)cn1 +Cc1ccc(C)c(N2CCN(c3nc(N)nc4nc[nH]c34)CC2)c1 +CC(C)OCCCNC(=O)Nc1ccnn1C1CCCCC1 +CCc1nc(CNC(=O)Nc2nc(C)ccc2OC)cs1 +Cc1ccc(NC(=O)NC(c2ccccc2)C(C)C)cc1C(N)=O +CS(=O)c1ccc(CNCc2nc(C(F)(F)F)cs2)cc1 +CCc1ccc(C(=O)Nc2ccc(F)cc2N)cc1 +CN1CC(NC(=O)c2cc(Cl)ccc2O)CCC1=O +O=C(NCC1CC1)N1CCC(c2ccc(O)cc2)CC1 +CCCOc1cccc(C(=O)N2CCN(CCC#N)CC2)c1 +Cc1ccc2oc(C(=O)OCC(=O)Nc3cc(C)on3)c(C)c2c1 +COCCNC(=O)Cn1cnc2cc(F)ccc2c1=O +CCOc1ccccc1NC(=O)Cc1ccc(OC)cc1 +Fc1cc(F)c2c(c1F)C(CC1=CCCCC1)NCC2 +O=C(C1CC=CCC1)N1CCN(c2cnccn2)CC1 +COc1ccc(OC)c(-n2cnnc2CN2CCOCC2)c1 +OCC1C=CC(Nc2nc(-c3cccnc3)nc3ccccc23)C1 +COc1cccc(-c2nnn(CC(=O)NCc3ccco3)n2)c1 +CN(CCOc1ccc(Cl)cc1)C(=O)C1COc2ccccc2O1 +CCSc1nc2cc(Cl)ccc2c(=O)n1N +CC(O)(CNC(=O)CCSc1ccccc1)C1CC1 +N#Cc1ccc(-c2noc(Cc3csc(-c4cnccn4)n3)n2)nc1 +CCCNC(=O)c1ccc(NCc2nnc(C3CC3)o2)cc1Cl +COCCN1CCN(S(=O)(=O)c2ccc(Cl)cc2C)CC1=O +CNC(=O)c1ccc(-n2c(-c3ccccc3)nc3cccnc32)cc1 +COc1ccc(Br)cc1S(=O)(=O)NC(C)(C)CO +CCn1c(C(N)c2cccc(NC(C)=O)c2)nc2ccccc21 +CCCC(=O)Nc1cc(C)nn1Cc1ccccc1 +Cc1noc(C)c1CN1CCOC2CCC1C2OCc1cccnc1 +CC(C)C(NC(=O)c1ccc(N2CCOCC2)cc1)C(C)C +C#CCNc1nc(C(C)(C)C)nc2c1nnn2Cc1ccccc1 +CS(=O)(=O)c1ccc(F)c(NC(=O)C2CC=CCC2)c1 +CCC(=O)NCC1CCCN(C(=O)Nc2ccc(C)cc2C)C1 +Cc1nc(NCc2ccco2)sc1C(=O)Nc1ccc(F)cc1F +CN(Cc1ccc(O)cc1)C(=O)NCCCC(C)(C)CO +Cc1nnc(-c2ccc3ccn(CC(=O)Nc4ccccn4)c3c2)o1 +COc1ccc(O)c2c1C(c1cc(F)cc(C#N)c1)NCC2 +Cc1nnc(SC(C)C(=O)Nc2cccc(Cl)c2)n1N +CCNC(=O)c1ccc(NC(=O)c2occc2C)cc1 +CSc1nnc(CCCNC(=O)c2cccnc2)n1C1CCCC1 +O=S(=O)(NCc1ccsc1)c1cccc2ccccc12 +Cc1cc(N2CCN(Cc3ccncc3)CC2)nc(C(C)C)n1 +O=C(Nc1cccc(-c2nnnn2C2CC2)c1)c1cc2ccccc2[nH]1 +CCN(c1ccccc1)C(C)C(=O)Nc1cccc(N)c1 +Cc1ccc(NC(=O)NCc2cccc(C(N)=O)c2)cc1Cl +Cc1cc(C(=O)NCC2Cc3ccccc3O2)c(C)n1C1CC1 +CSc1ncccc1C(=O)NCC1(c2ccccc2)CCOCC1 +CC(CNC(=O)c1scnc1C1CC1)c1cccs1 +O=C(NCc1cccc2cccnc12)N1CCc2cc(F)ccc2C1 +Cc1ccc(S(=O)(=O)Nc2cn[nH]c2)cc1F +O=C(c1cccc(CO)n1)N1CCCCC1CCc1ccccc1 +CC(C)N(CCCO)C(=O)Nc1ccc(F)cc1 +N#Cc1ccc(OC(F)F)c(NC(=O)NCC(O)c2ccco2)c1 +COc1ccc2cc(NC(=O)COc3coc(C)cc3=O)cnc2c1 +CNC(=O)c1cccnc1NCc1ccccc1COC(C)C +O=C1CN(C(=O)c2ccc(Cl)cc2F)c2ccccc2N1 +CCOC(=O)C1CC(=O)N(c2nc3ccccc3s2)C1 +Cc1nc(-c2cccnc2)nc(NCC(O)c2ccco2)c1C +CC(CCCO)NC(=O)c1cc(F)cc(Cl)c1O +COc1ccnc(NC(=O)c2ccc(-c3nc(C)no3)cc2)c1 +Cc1nc2ccccn2c(=O)c1NC(=O)Cc1ccc(F)cc1 +CCC1CN(C(=O)CCN2C(=O)COc3ccccc32)CCO1 +O=C(NCc1cccc(F)c1)c1cc2cccnn2n1 +Cc1ccccc1C(=O)Nc1ncc(C(N)=O)s1 +Cc1ccccc1CN(Cc1cccnc1)C(=O)Cn1cnnn1 +Cc1n[nH]c(C(=O)N(C)CC(=O)NC2CC2)c1Br +CS(=O)(=O)NCC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CNc1nn(-c2ccc(OC)cc2)c2c1C(=O)CC(c1ccco1)C2 +O=C(CCc1cccnc1)Nc1ccccc1OCC1CC1 +c1cc(-c2cn(CCCn3cncn3)nn2)cc(-n2cccn2)c1 +CN(Cc1cc(Br)cs1)c1ncnc2nc[nH]c12 +CCC(CO)Nc1ncnc2c1cnn2-c1ccc(Cl)cc1 +CC1CC(CC(=O)NC(C)C(=O)N2CCCCC2)CC(C)(C)C1 +Cc1cccc(CN2CCc3ncnc(-c4ccncc4)c3CC2)n1 +O=C1N=C(NC(=O)Nc2ccc(Cl)cc2)C(c2ccccc2)=N1 +COc1ccnc(NC(=O)c2ccc(C#N)cc2C)c1 +CSc1cccc(NC(=O)Nc2cc(NC(C)=O)ccc2F)c1 +CCCc1c(C(=O)N(C)C)cnn1-c1cccc(Cl)c1 +CNS(=O)(=O)c1cccc(C(=O)N(C)CC(C)C)c1 +CN(Cc1ccc(Br)cc1)C(=O)NCC1CCCO1 +CC(Nc1ncnc2c1cnn2-c1ccccc1)c1ccccc1 +Cc1ccnc2nc(C(=O)Nc3cnc4c(cnn4C(C)C)c3)nn12 +Cc1cccc(NC(=O)CNC(=O)OCC(F)(F)F)c1 +O=C(OCC(=O)N1CCc2ccccc21)c1ccco1 +COc1ccc(F)cc1NC(=O)c1ccc(Br)c(O)c1 +CCC(C)NC(=O)c1cc(C2CC2)nc2ccccc12 +CCc1nc(-c2ccc(NC(=O)NCCN3CCOCC3)cc2)no1 +COCC(NC(=O)c1scnc1C1CC1)C1CC1 +COc1cc(OC)c(NC(=O)c2ccncc2F)cc1F +CC(C)COc1ccc(C(=O)NCc2ccncc2)cc1N +N#CCCCCS(=O)(=O)c1ccc(F)c(F)c1 +Nc1ncccc1C(=O)OCC(=O)NC1CCCCCC1 +COc1cc(Br)c(CNC(=O)N2CCCC2)cc1OC +CC(=O)c1ccc(N2CCN(CC(=O)NC3CCCCC3)CC2)cc1 +CCOc1ccc(C(=O)NCc2csc(=O)[nH]2)cn1 +CCOc1ccc(C(=O)N2Cc3nnc(C)n3C(C)C2)o1 +CCOC(=O)c1cnn(-c2ccccc2)c1NC(=O)c1ccccc1C +CNC(=O)c1cc(Cl)ccc1NC(=O)c1ccc2ccccc2n1 +COc1ccc(N2CCN(CC(=O)N(CCO)C(C)C)C2=O)cc1 +C#CCCNC(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)n[nH]1 +CN(CC(=O)NCCC1=CCCCC1)Cc1ccc(C#N)cc1 +Oc1ccc(Br)c2c1CCNC2c1ccc[nH]1 +Cc1cccc(O)c1NS(=O)(=O)c1cn[nH]c1 +CCCCOC(=O)CCN1C(=O)COc2ccccc21 +OCc1ccc2nc(-c3cc(F)ccc3F)cn2c1 +CN(C)S(=O)(=O)NC1CC(C)(C)Cc2nc(C(C)(C)C)ncc21 +CCC(Cc1ccccc1Br)C(=O)NCc1ncc[nH]1 +CCCCn1nc(-c2nnc(NCCC)s2)ccc1=O +CCOCCCC(=O)N1CC(C)Sc2ccccc21 +CC(CCO)NC(=O)Nc1ccccc1C(F)(F)F +CCn1cnnc1CNC(=O)Nc1cc(F)ccc1Br +Cc1ccc(C(N)=O)c(OCC(=O)NC(C)Cc2ccccc2C)c1 +COC(=O)C1CCc2nc(Cc3cccs3)nn2C1 +O=S(n1cnc2ccccc21)n1cnc2ccccc21 +Cc1nc(-c2ccccc2)sc1CNC(=O)c1ccc[nH]c1=O +O=C(CCCNC(=O)c1cccn2cncc12)Nc1ccc(F)cc1 +Cc1ccc(C(=O)N(C)CCOc2ccccc2F)s1 +Cc1cc(CS(=O)(=O)c2ccc(F)c(F)c2)no1 +COc1cccc(C(=O)NCCc2ccc(NC(C)=O)cc2)c1F +Cc1cccc(OCC(=O)Nc2ccc3c(c2)COC3)c1 +Cc1ccc(C#N)cc1NC(=O)CSc1nncs1 +COC(=O)c1cn(Nc2ccc(F)cc2)cc(C(=O)OC)c1=O +C=CCN(CC=C)C(=O)c1ccc(NC(=O)C2CC3C=CC2C3)cc1 +CN(C)C(=O)c1ccc(N2Cc3cnc(C(C)(C)C)nc3C2)nc1 +Cc1nc(C(=O)NCCCCOc2ccccc2)cs1 +O=C(Nc1cc(F)ccc1F)c1ccc2[nH]cnc2c1 +Cc1nn(C)c(C)c1C(=O)N1CCN(C(=O)CCC(C)C)CC1 +Cc1csc(NC(=O)NC2CCN(c3c(F)cccc3F)C2)n1 +O=C(c1cccc(N2CCNC2=O)c1)N1CCc2ccccc2C1 +CCS(=O)(=O)N(C)C(C(N)=O)c1cccc(F)c1 +NC(=O)C1(NC(=O)COc2ccc(F)c(Cl)c2)CCCCC1 +O=C(c1ccco1)N1CCN(c2nc3ccccc3n3nnnc23)CC1 +CCc1nc(CC(=O)N2CCn3c(CC)nnc3C2)cs1 +O=C1CN(C(=O)C2CCC(=O)N(CCc3cccc(F)c3)C2)CCN1 +COc1c(C(=O)OCCc2ccc(F)c(F)c2)cnc2c1cnn2C +CCCC(C)(C)NC(=O)NCc1cc(=O)[nH]c2ccccc12 +CCOC(=O)C1CCN(C(=O)c2cc(C)ccc2C)CC1 +CC(=O)NCC(=O)N1CCC(Oc2ccccc2)CC1 +Cc1ccc(CNC(=O)NCC2Cc3ccccc3O2)c(N(C)C)c1 +Cc1cc(CN(CCC(N)=O)c2ccc(F)cc2)no1 +CSc1ncccc1C(=O)OCc1nc2ccccc2o1 +CC(=O)OCc1ccc(C(=O)NC(C)C(N)=O)cc1 +CNC(=O)CN1CCCCC1c1nc2ccccc2s1 +CC(C)c1ccc2c(c1)CNCC2C(=O)NC1CCCC1 +CCOC(=O)C1CCN(C(=O)CNc2cc(F)ccc2Cl)CC1 +CC(O)(CNc1ncnc2ccc(F)cc12)c1ccsc1 +O=C1CC(NS(=O)(=O)c2cccs2)CN1Cc1ccccc1 +Cc1ccc(C(=O)Nc2ccc(Cl)cc2N)cc1 +Cc1noc(CCC(=O)N2CCCCC2C(N)=O)n1 +C=CCC1CC=CC(C)N1C(=O)CSc1nc(CC)n[nH]1 +CCN(CC(C)C(=O)OC)C(=O)C(C)c1ccsc1 +COc1ccc2cc(C(=O)Nc3nc(C)c(C)s3)c(=O)oc2c1 +C=CCOc1c(Br)cc(C#N)cc1OCC +Cc1cnc(CNC(=O)c2cccc3ccnn23)cn1 +COCCCNC(=O)c1ccn2c(-c3cc(F)cc(F)c3)nnc2c1 +COc1ccc(CC(=O)Nc2c(C)nc3c(C)cccn3c2=O)cc1 +CC(C)(C)NS(=O)(=O)Cc1cccc(NC(=O)C2CCC2)c1 +Cc1ccsc1C(=O)Nc1cccc(Cn2ccnc2)c1 +Cc1cccc(SCC(=O)Nc2ccc(S(C)(=O)=O)cc2)c1 +CCOC(=O)C1CCN(C(=O)c2cnc(C)[nH]c2=O)CC1 +O=C(NC1(c2ccc(Cl)cc2)CC1)c1ccc(F)nc1 +CS(=O)(=O)N1CCN(c2cnnc(N3CCCC3)c2)CC1 +Cc1ccc(CN(C)C(=O)Nc2ccn(C)n2)cc1 +O=C(c1ncccn1)N1CCC(Oc2ccccn2)C2OCCC21 +CCOc1ccc(C(=O)N2CCN(Cc3ccccc3)CC2)nn1 +O=C(C1Cc2ccccc2O1)N1CCN(Cc2cscn2)CC1 +CC(NC(=O)COc1ccccc1)c1ccc(F)c(F)c1 +COc1ccccc1-n1nnc(C#N)c1-c1cccc(C)c1 +CNC(=O)NCCOc1ccccc1-c1ccccc1 +Cc1noc(CCCC(=O)Nc2cccc(-c3nc(C)c(C)o3)c2)n1 +Cc1cc(NC(=O)C(C)Nc2ccc3oc(C4CC4)nc3c2)no1 +Cc1ccc(C)c(NC(=O)COC(=O)c2ccc(N)cc2)c1 +CCc1n[nH]c(C2CCN(C(=O)c3ccccc3)CC2)n1 +CC(OC(=O)C1CC(=O)N(Cc2ccco2)C1)c1cc(F)ccc1F +COC(=O)C(C#N)c1nc2ccccc2nc1NCc1ccccn1 +CCC1CN(C(=O)Nc2ccccc2-n2nc(C)nc2C)CC(C)O1 +Cc1ccsc1CNC(=O)C(C)n1cncn1 +O=C(CCC(O)c1ccc2c(c1)OCO2)NCc1cccnc1 +CN(C)c1nc(-n2ccnc2)nc(-n2ccnc2)n1 +CC(C#N)NS(=O)(=O)c1cncc(Br)c1 +O=C(c1cc(F)ccc1Br)N1CCCCC1 +CS(=O)(=O)c1ccc(CNC(=O)CCC=Cc2ccccc2)cc1 +Cc1cccc(C(N)C(=O)NCCC(C)(C)C)c1C +COC(=O)c1cncc(C(=O)NCCC2CC3CCC2C3)c1 +Cc1ccc(OCCNC(=O)Cc2csc(C)n2)cc1 +CCc1nn(-c2ccc(C(F)(F)F)cc2)c2c1CNCC2 +c1nc2n(n1)-c1nncn1-c1sc3c(c1-2)CCC3 +Cc1c(C(=O)Nc2nc3c(s2)CCCC3)oc2ccc(F)cc12 +O=C(CCCOc1cccc(F)c1)OC1CCOC1 +Cc1ccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)c(O)c1 +Cc1cccc2c(=O)n(CC(=O)N3CCc4sccc4C3)cnc12 +CNC(=O)c1cccc(C(=O)NCC(O)C2CCCCC2)c1 +CC(C)COc1cccc(C(=O)NC(C(N)=O)C(C)(C)C)c1 +O=C(NCc1nc(-c2ccc(Cl)cc2)no1)c1ccc(F)cc1 +CN(C)c1ccc(-c2nc3ccc(N)cc3[nH]2)c(F)c1 +CC(C)CC1COCCN1CC(=O)NCC1COc2ccccc2O1 +CCC(=O)NCc1cccc(S(=O)(=O)N2CCCCC2)c1 +O=S(=O)(c1ccc2c(c1)CCN2)N1CCCCC1 +CC(C)S(=O)(=O)N1CCC(NC(=O)c2cccs2)CC1 +COc1cccc2c(C(C)=O)c3c(nc12)CCN(C)C3 +CCOC(=O)c1coc(-c2cccc(Br)c2)n1 +O=C(NC1CCc2ccccc21)N1CCC(C(O)C(F)(F)F)CC1 +Cc1cc(NC(=O)CN2CCc3cc(Br)ccc32)on1 +CCc1c(C)nc(N2CCN(c3ccccn3)CC2)[nH]c1=O +O=S1(=O)CCCN1Cc1ccc(F)cc1Br +COCC(O)CN1CCOC(c2nc(C)n[nH]2)C1 +Cc1cc(C(=O)Nc2ccc(C)c(C)c2)c2c(C)noc2n1 +O=C(Nc1cccc2cnccc12)C1COc2ccccc21 +O=C(c1cccs1)N1CCN(C(=O)C2CCCCC2)CC1 +CC(=O)NC(CC(=O)Nc1ccc(F)c(F)c1F)c1ccccc1 +Cn1c(C(=O)Nc2ccc(C(N)=O)cc2)cc2occc21 +CCOc1c(Cl)cc(C(=O)NC(C)CO)cc1OC +Cc1ccc(Cl)cc1-n1ncc2c(NCC3CCCO3)ncnc21 +COCC1CN(C(=O)Cc2ccccn2)Cc2c1cnn2CC1CC1 +CCNC(=O)N1CCC(COCc2cc(OC)cc(OC)c2)CC1 +COc1cccc(OC)c1C(=O)N(C)CC(O)C1CC1 +CC(NC(=O)C1CC1c1ccc(F)c(F)c1)C(N)=O +CS(=O)(=O)c1cc(C#N)cc(S(C)(=O)=O)c1 +C=CCCCN(C)C(=O)c1ccc(-n2ccnc2)nc1 +Cn1cc(C(=O)CSc2ccc(F)cc2)cn1 +CCCOc1ccccc1-n1nnc(C#N)c1-c1cccnc1 +Cc1nnc(-c2ccc(NC(C)c3cccnc3)cc2)o1 +N#CCn1cnc2c(nnn2-c2cccc(F)c2)c1=O +Cn1cnc(CNC(=O)c2[nH]c3ccccc3c2Br)n1 +COc1ccccc1NC(=O)Cc1c(C)nc2nc(N)nn2c1C +O=C(c1ccncc1Cl)N1CCCCC1c1nc[nH]n1 +Nc1ccc(Cl)c2c(NCc3ccccn3)nccc12 +Cc1cnc(NC2CS(=O)(=O)c3ccccc32)s1 +COc1ccc(CCNC(=O)c2ccc3ncccc3n2)cc1OC +O=C1CCCCN1Cc1cccc(NC(=O)N2CCCCCC2)c1 +COC(=O)CC1(CNC(=O)CC#N)CCCCC1 +CC(=O)Nc1cccc(NC(=O)N(C)C(C)c2ccccc2F)c1C +Cc1cc(NC(=O)C2CCCOC2)ccc1Br +COC(=O)c1ccc(C(=O)NC2CCCCC2C)cn1 +COc1cccc2c1OCC(C(=O)NCC(=O)Nc1nccs1)C2 +CCCn1nccc1C(=O)NCCCN1CCOCC1 +NC(=O)c1c(NC(=O)c2ccccc2F)sc2c1CCCC2 +Cc1ccc(CNCC(=O)Nc2c(C)cccc2C)cc1F +COc1ccccc1-n1cc(CN(C)C(C)Cc2cnccn2)cn1 +CN(C(=O)CCc1ccccc1N)c1ccccc1 +Nc1occ2ncn(-c3ccc(Br)cc3)c12 +CCOC(=O)N1CCN(C(=O)NCCNC(C)=O)CC1 +N#Cc1ccnc(N2CCN(Cc3ccn(-c4ccccc4)n3)CC2)c1 +CC(C)c1nn(C)cc1CN(C)C(=O)Nc1ccc2c(c1)COC2 +O=C(NCCNC(=O)C1CC1)c1ccccc1F +COc1cc(C(=O)NCc2ccc(NC(=O)C3CC3)cc2)ccc1C +CN(c1ncccn1)C1COC2(CCN(C(=O)c3ccsc3)C2)C1 +COc1ccc(CCNc2nc(C)c(C(C)=O)s2)cc1OC +Cc1ccc(F)c(N2CCN(C(=O)CC(C)C)C(C)C2=O)c1 +CCC(C(=O)Nc1cccc(C#N)c1)n1cc(C)ccc1=O +O=C(Cc1csc(-c2cccs2)n1)OCC1CCCO1 +O=c1nc(SCc2ccc(F)cc2)c2c(n1CCCO)CCCC2 +Cn1cnc(-c2ccc(F)cc2)c1NC(=O)COC1CCCCC1 +CCOc1c(Cn2ccnc2-c2ccoc2)cccc1OC +Cc1nn(C)c(C)c1C(=O)NCC(C)(O)c1ccc(F)cc1 +COc1cccc(-c2c(C#N)c(N)nc3c2CN(C(=O)C2CC2)CC3)c1 +COCCC(C)C(=O)NC(C)c1ccc(-n2ccnc2C)cc1 +Cc1nc(CN(C)c2nc3ccccc3s2)cs1 +CCC1c2ccsc2CCN1C(=O)CSc1nc(C)c(C)o1 +O=C(NCC(O)c1ccc(F)c(F)c1)c1nccc2ccccc12 +Cc1csc(CN(C)C(=O)c2ncccc2OCC(F)(F)F)n1 +CNC(=O)c1cccc(OC(=O)CSc2ccc3c(c2)CCC3)c1 +Cc1ccc(NC(=O)CCNC(=O)N2CCOCC2C2CC2)nc1 +CCc1ncc2c(n1)CN(C(=O)c1ccc(N3CCCC3=O)cc1)C2 +CC(Sc1nnc(Cc2ccccc2)o1)C(=O)NCC1CCCO1 +CC(=O)Nc1ccc(NC(C)c2cccnc2)cc1 +Cc1cc(C(=O)N(CC(N)=O)C2CCCC2)c2c(C)nn(C)c2n1 +O=C(CC1CCCC1)NCCNC(=O)NC1CCCCCC1 +COCCNC(=O)c1nn(C)c2ccc(C)cc2c1=O +Cc1c(Cl)cccc1NC(=O)Cc1coc2ccc(F)cc12 +O=C(COC(=O)c1ccc(F)cc1)Nc1c(F)cccc1F +Cc1cccc2c1ccn2CCNC(=O)c1ccncc1 +CCn1cc(-c2ccc(Cl)cc2)cc1C(=O)N(C)C +Cc1ccc(NC(=O)CCc2c(C)[nH]c3ncnn3c2=O)c(C)c1 +CCCN(C)C(=O)C1CCCN(c2cnc3nccnc3c2)C1 +CCCN(C)C(=O)c1cc(COc2ccc(F)c(F)c2)on1 +CCOC(=O)Cn1ncn(-c2ccc(Br)cc2)c1=O +COc1cccc(CC(=O)Nc2ccc(O)cc2C)c1 +COc1ccc(Cc2nc(C)c(C(C)=O)o2)cc1F +COc1cccc2c1OCC(NC(=O)N1CCCC(O)C1)C2 +CN(Cc1ccccn1)C(=O)NCC(=O)N1CCCC1 +CC(CCc1ccc(O)cc1)NC(=O)N(C)CC1CCCO1 +Cc1ccc(CN(C(=O)C(C)NC(N)=O)C(C)C)o1 +CCS(=O)(=O)N1CCC(C(=O)NCc2cccc(C)c2)CC1 +CC(=O)Nc1cccc(NC(=O)c2ccc(Cl)c(N)c2)c1 +CC(CCn1cccn1)Nc1nc(C2CCCC2)nc2c1cnn2C +CNC(=O)c1ccc(S(=O)(=O)C2CCCC2)cc1 +Cc1cccc(C2NCCc3cc4ccccc4cc32)n1 +O=C(Cc1ccccc1Cl)N1CCC2(CC1)OCCCO2 +COc1cccc(OC)c1C(=O)Nc1cccc(NC(=O)C(C)C)c1 +N#Cc1cccnc1N1CCCC(CO)(Cc2ccc(F)cc2)C1 +CN(CC1CCOC1)S(=O)(=O)c1csc2ccc(Cl)cc12 +Cc1cc(C)n2c(-c3ccccc3)c(C)c(C(N)=O)c2n1 +CC(C)CNC(=O)c1cccc(OCC(F)F)n1 +CC1(C)C(=O)N(CC(=O)NCc2cccnc2)c2ccccc21 +COc1c(F)c(F)c(C(=O)Nc2ccccc2C(N)=O)c(F)c1F +Cc1nc(CNC(=O)c2cc(S(C)(=O)=O)ccc2F)sc1C +CS(=O)(=O)c1ccc(Oc2ccc(NC3CCOC3=O)cc2)cc1 +CCOC(=O)C1CCN(c2nc(C)nc3sc4c(c23)CCC4)CC1 +COc1ccccc1C(=O)Nc1ccc(NCC(C)O)nc1 +Cc1n[nH]c(C)c1NC(=O)COc1cc(Cl)ccc1Cl +CCN(Cc1cccc(F)c1)C(=O)NCC1CN2CCCCC2CO1 +COc1cc(OC2CC2)ccc1NS(C)(=O)=O +CCC(=O)Nc1ccc(NCC(=O)N2CCC(C)CC2)cc1 +COc1ccccc1CNC(=O)CCn1ccnc1 +COc1cc2c(cc1OC)CCN(C(=O)c1cc(C)no1)CC2 +Cc1cccc(CNC(=O)c2ccc(Cc3c(C)noc3C)o2)c1 +O=C1CCCCN1CSc1ncnc2c1cnn2-c1ccccc1 +O=C(C1CCCO1)N1CCc2nc(N3CCOCC3)[nH]c(=O)c2C1 +Cc1ccc(S(=O)(=O)N(C)c2ccccn2)c(N)c1 +CC(CC(=O)N1CCN(C(=O)c2cc3ccccc3[nH]2)CC1)C1CC1 +CCN(Cc1cccc(C)c1)C(=O)Nc1cccnc1-n1cncn1 +CSc1nnc2n(C)c(=O)c3c4c(sc3n12)COC(C)(C)C4 +CCCOc1ccc(CNc2ncnc3ccc(F)cc23)cc1 +O=C(c1cn[nH]c1)N1CCN(c2cnccn2)CC1 +Cc1nonc1C(=O)NCc1ccccc1-n1ccnc1C +N#CC(C(=O)c1ccc(F)c(F)c1)c1nc2ccccc2[nH]1 +Cc1nnc(N2CCN(c3ccc(F)cc3)CC2)c(C#N)c1C +Cc1nc(CSc2nc(-c3ccccn3)n[nH]2)sc1C +Cc1c(CNS(=O)(=O)c2cccc(COC(C)C)c2)cnn1C +COC(=O)C1=C(C)N=C(C)C(C(=O)OC)C1c1cscn1 +CCc1cc(=O)[nH]c2nnc(SCC(=O)NCCOC)n12 +Cc1cccc2[nH]c(SCC(=O)N3CCOCC3)nc12 +CCN(CC(=O)NCc1ccc(Cl)cc1)C(=O)c1ccoc1 +O=C(NC1CNCc2ccccc21)c1ccc(C(F)(F)F)cc1 +Cc1nc2cc(C(=O)N(C)Cc3ccno3)ccc2s1 +O=C(NCC#Cc1ccc(N2CCCCC2=O)cc1)c1cccnc1 +N#Cc1ccc(-c2noc(-c3ccc(Cl)cc3F)n2)nc1 +CC1COCCN1S(=O)(=O)c1cc(N)cc(F)c1 +O=C(Nc1ccccc1-n1cnnn1)c1ccc(-n2ccnn2)cc1 +Nc1nccnc1C(=O)OCC(=O)NCCc1ccc(Cl)cc1 +O=C(NC1CCN(c2ccccc2)C1=O)c1ccncc1F +COc1ccc(CNS(=O)(=O)c2cccc(C(C)=O)c2)cc1 +CCc1ccc(NC(=O)CS(=O)(=O)c2cccc(C)c2)cc1 +COc1ccc(Br)c(CC2C(=O)Nc3ccccc32)c1 +Cc1cc2c(c(=O)o1)C=C1C(CC3CC1C3(C)C)O2 +CCN(C(=O)COc1cccc(C(=O)NC2CC2)c1)C1CCCCC1 +O=C(Nc1cc(C(F)(F)F)ccc1N1CCCCC1)c1ccncc1 +COc1cccc(C(C#N)NC(=O)OC(C)(C)C)c1 +Cc1ccc(CC(=O)Nc2ccccc2OCC2CCCCO2)cn1 +CC(C)(C)OC(=O)N1CCCC1COCc1cncs1 +Cc1cnn(CC2CN(c3nn4cc(C)nc4s3)CCO2)c1 +Cn1ncc(C(=O)NCc2cn[nH]c2)c1-n1cccc1 +COc1ccc2c(C(=O)NCCc3cccc(F)c3)cc(=O)oc2c1 +CNC(=O)COC(=O)C1CC(=O)N(c2cc(Cl)cc(Cl)c2)C1 +CC(C)S(=O)(=O)N1CCN(c2ccc(Br)cn2)CC1 +O=C(OCc1ncc(-c2ccccc2)o1)C1CC2CCC1O2 +Cc1oc(CO)cc1C(=O)OCC(=O)NC1CCCC1 +CCOCC1CCCN(S(=O)(=O)c2cc(Cl)ccc2C#N)C1 +N#Cc1cccc(C(=O)NCC2(c3cccs3)CCOCC2)c1 +CC(C)(C)OC(=O)Nc1cccc(-c2cnc(=O)[nH]c2)c1 +COc1ccc(C(=O)COc2ccc(F)cc2F)cc1OC +Cc1nc2ccccn2c1C(=O)Nc1cc(N2CCCCC2)ncn1 +CCOCC(=O)N1CCN(C(=O)C2CCCC2)CC1 +CCN(C(=O)C1COc2ccc(F)cc2C1)C(C)c1cccnc1 +CC(C)(CNC(=O)c1ccccc1Br)NS(C)(=O)=O +Cc1ccc(O)c(C(=O)Nc2ccc(N)cc2Cl)c1 +COc1cc2c(cc1OC)CCN(C(=O)c1ccc(C)o1)CC2 +CC(C)n1nccc1NC(=O)COC(=O)c1ccc(NC(N)=O)cc1 +CC=CCOC(=O)CCc1nc(-c2ccc(C)c(F)c2)no1 +COc1ccc(C(=O)Nc2cc(OC)ccc2F)cc1 +Cc1nn(C)c(C)c1CC(=O)Nc1ccccc1C(=O)C(C)C +CC(C)Nc1nnc(SCC(=O)c2ccc3c(c2)OCO3)s1 +Cc1cccc(-n2ncc3c(NC(C)(C)CO)ncnc32)c1 +COCc1csc(NC(=O)N2CCCC2CN2CCOCC2)n1 +O=C(CS(=O)(=O)c1ccc(C(F)(F)F)cn1)N1CCCC1 +COC(=O)c1ccc(OC(C)C)c(NC(=O)N2CCCC2)c1 +Cc1ccc(-c2nnn(CC(=O)NCc3ccco3)n2)cc1 +O=C(c1cscn1)N1CCC(O)C1Cc1ccccc1 +COc1ccccc1-c1onc(C)c1C(=O)NCCc1cccs1 +CC(C)(C)C(=O)N1CCN(c2ccc(N3CCOCC3)nn2)CC1 +CC(NS(=O)(=O)c1ccccc1F)C(=O)Nc1cccnc1 +CC(COc1ccccc1)OC(=O)C1COc2ccccc21 +Cc1ccc(SCC(F)(F)F)c(NC(=O)c2cccnc2)c1 +Nc1cc(F)cc(S(=O)(=O)NCC2CCCCO2)c1 +COc1ccccc1OCCC(=O)Nc1nc(-c2ccco2)cs1 +CCCNC(=O)CNc1ccc2nc(C(C)C)sc2c1 +CC(CNC(=O)N1CCCC1C(=O)NC1CC1)c1ccsc1 +O=C(NC1=CC=CC2N=CC=C12)c1cccc(C(F)(F)F)c1 +OC(CNc1nn2cc(-c3ccccc3)nc2s1)c1ccccc1 +CC1CN(C(=O)C(NC(=O)c2ccco2)C(C)C)CC(C)O1 +C=CCN(Cc1cccs1)C(=O)Cc1ccc(NC(C)=O)cc1 +Cn1c(N)c2c(=O)n(C)c3c(c2c(C#N)c1=O)CCC3 +COC(=O)C(C)Nc1nc2cc(OC)c(OC)cc2[nH]1 +Cc1noc(CNC(=O)NCCc2ccccc2)n1 +O=C(CC(c1ccccc1)c1ccccc1)NCCc1nccs1 +COc1cccc(C2(NC(=O)c3cnn(-c4ccncc4)c3C)CC2)c1 +COC(=O)c1ccc2[nH]cc(Br)c2n1 +O=C(NC1C(c2ccccc2)CC(O)C1O)c1ccno1 +NS(=O)(=O)c1cccc(NS(=O)(=O)c2ccc(F)cc2)c1 +Cc1cc(SCc2cc(C#CCO)cs2)n(C)n1 +CCCCNC(=O)C1(NCc2nc(C)no2)CCCCC1 +COC(=O)c1ccc(NC(=O)Cc2cn3ccccc3n2)cc1 +Cc1ccc(C(=O)NC(C)Cc2cccc(Cl)c2)c(=O)[nH]1 +COc1ccc(-c2nnn(CC(=O)Nc3ccc(F)cc3)n2)cc1 +Cc1ccccc1NC(=O)CC1(CC(=O)N2CCOCC2)CCCC1 +COCC(C)NC(=O)c1ccccc1S(C)(=O)=O +O=C(Nc1c(F)cccc1Oc1ccccc1)N1CCC(O)C1 +CC(=O)Nc1cccc(NC(=O)c2cc(C(N)=O)cn2C)c1 +COC(=O)COc1ccc(C(=O)OC)cc1Br +CCCNC(=O)C(C)NC(=O)Nc1ccc(SC)cc1 +CCOc1ccc(NC(=O)Cn2ccccc2=O)c(C)c1 +Cc1ccc2[nH]c(=O)c(CCC(=O)N(C)CCc3ccccn3)cc2c1 +Cc1ccc(C(=O)Nc2c(F)cccc2Oc2ccccc2)c(=O)[nH]1 +COc1cccc(Nc2nc(NCCO)c3ccccc3n2)c1 +CCCn1c(SCC(=O)N(C)C)nnc1-c1cccc(C)c1 +Cc1cc(=O)oc(C)c1C(=O)N1CC2CC(C1)c1cccc(=O)n1C2 +COC(=O)C1CCN(CC(=O)c2ccccc2)CC1 +Cc1cc(NC(=O)C(Cc2ccccc2)NC(=O)C(C)C)no1 +CCC(C)NC(=O)C(C)NC(=O)c1csc(C)n1 +Cc1noc(C)c1CCC(=O)Nc1cccc(Cl)c1-n1cccn1 +Cc1cccc(NC(=O)N2CCC3(CC(=O)N(c4ccccc4)C3)C2)c1 +CCc1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1N +COc1cccc(C(O)CN(C)c2ccccc2)c1 +COc1c(C)cc(C(=O)CN2CC(C)OC(C)C2)c(C)c1C +O=C(CN1C(=O)CSc2ccccc21)Nc1cccc2[nH]ccc12 +CCNc1nc(C)c(CN(C(C)=O)c2ccccc2)nc1C#N +COc1ccc(Cl)cc1N(C)C(=O)CC(C)(C)C +COC(=O)c1ccccc1OC(=O)CCc1c(C)nn(C)c1C +COc1cccc(OCC(=O)NCC2Cc3ccccc3O2)c1 +Cn1cc(CN2CCC23CCN(c2cnccn2)C3)cn1 +CNS(=O)(=O)c1cccc(C(=O)OCC(=O)NC2CC2)c1 +Cc1nn(C)c(=O)c(C(=O)NCCOc2ccc(C(C)C)cc2)c1C +Cc1cccc(CC(=O)Nc2nc3n(c2C#N)CCS3)c1 +CC(=O)Nc1cc(NC(=O)Nc2cc(C)cc(C)n2)ccc1C +CCS(=O)(=O)N1CCC(NC(=O)Cc2ccccc2F)CC1 +COc1cc2c(cc1Cl)C(CN(C)C)NCC2 +CCCC1CN(C(=O)C2(c3cccc(F)c3)CCC2)CCO1 +CCOc1ccc(C(C)NC(=O)Cc2c(C)noc2C)cc1 +COc1ccc(Cc2cc(=O)[nH]c(NCCc3cnccn3)n2)cc1 +CCc1ccc(CNC(=O)Nc2cc(C)nn2C)s1 +Cc1nn(C)c(C)c1C(=O)Nc1cccc(OCC(N)=O)c1 +CCCc1cc(C(=O)NC(C)Cn2ccnc2)sc1C +Cc1cccc(C(=O)NCC(=O)NCc2ccc(C)cc2N(C)C)c1 +COc1ccc(OCCC(=O)NC2(C#N)CCCCC2)cc1 +CCCn1c(C)cc(N2CCC(C)CC2)c(N)c1=O +CC(=O)Nc1cccc(CNC(=O)N(Cc2ccccc2)C2CC2)c1 +COc1ccc(CCC(=O)N2CCN(Cc3ccnn3C)CC2)cc1 +Cc1ccc2c(c1)C(NC(=O)C1CC1)CC1(CCOCC1)O2 +N#Cc1ccc(OCc2cnn(-c3ccccc3)n2)c(Cl)c1 +CC(C)COCCC(=O)N1CCN(C(=O)CO)CC1 +Cc1ncc(C(C)NCC2(c3ccc(F)cc3)CCOCC2)s1 +Nc1ccc(F)cc1C(=O)NCc1ccccc1Cl +CCc1c(C)nc(SCC(=O)NC(C)C)[nH]c1=O +Cc1ccc2c(c1)CNCC2C(=O)Nc1cccnc1 +c1ccc(CN2CC(c3nc(-c4cnccn4)no3)C2)nc1 +O=C(Cn1c(=O)cnc2ccccc21)Nc1ccc(C(F)(F)F)cc1 +Cn1cc(CCNC(=O)NC2CCSc3ccccc32)cn1 +COc1ccc2c(=O)cc(C(=O)NCCc3ccc(C)o3)oc2c1 +COCc1cc(C(=O)Nc2cccc(N3CCOC3=O)c2)ccc1F +CCC1CN(CCn2cccn2)CCN1CC(O)c1ccccc1F +N#CC(Cc1ccc(F)cc1)C(=O)N1CCOCC1 +CCOc1ccc(NS(=O)(=O)c2cc(C(N)=O)sc2C)cc1 +CN(C)C=C(NC(=O)Nc1ccccc1F)C(F)(F)F +O=c1[nH]nc(CCCN2CCOCC2)n1-c1cccc(Cl)c1 +CC(C)NC(=O)CSc1nc2ccccc2c(=O)n1C +Cc1noc2ncnc(NC3CCCN(C(=O)c4cccs4)C3)c12 +CSc1nc(=O)c2cnn(-c3ccc(C)c(C)c3)c2[nH]1 +Cc1cc(Br)ccc1NC(=O)c1ccc(N(C)C)nc1 +Cc1ccc(S(=O)(=O)NCC(O)c2cccs2)cc1 +Cn1cc(NC(=O)NCC2(c3cccc(F)c3)CCOCC2)cn1 +COc1ccc(NC(=O)c2n[nH]c3ccc(C)cc23)c2cccnc12 +Cc1ccc(-c2nnc(NC(=O)c3ccnn3C)o2)cc1C +COc1ccc(NC(=O)c2ccoc2)cc1Cl +CCn1ncc(C(=O)N(Cc2ccccn2)Cc2ccco2)c1C +O=C(Nc1cccc(F)c1)c1cccc2c1NCCC2 +Cn1ncc2c(N3CCN(C(=O)N4CCOCC4)CC3)ncnc21 +CC(=O)c1nc(C)n(-c2c(Cl)cc(Cl)cc2Cl)n1 +CCCc1noc(CSc2nc(-c3cccnc3)n[nH]2)n1 +Cc1ccc(CNC(=O)c2ccc(CNC(=O)OC(C)(C)C)o2)n1C +COCCCN1CCN(C(=O)c2cnc(C(C)(C)C)[nH]c2=O)CC1 +COCCN1CCOC2CCN(C(=O)c3ccnnc3)CCC21 +CC(=O)c1ccc(NC(=O)CC(C#N)c2cccnc2)cc1 +COc1ccc(Cl)c2c3c(cnc12)C(=O)NCCN3 +C#CCN(Cc1ccc(F)cc1)C(=O)NCC1CN2CCCC2CO1 +COC(C)c1nc(C)c(C(=O)Nc2cc(C)cc3cccnc23)s1 +CCCOc1ccc(-c2nc3ccccn3c2CO)cc1 +NC(=O)CC1CCN(C(=O)Cn2cnc3ccc(F)cc3c2=O)CC1 +Cc1ncsc1C(=O)N(Cc1ccccc1)C(C)C1CC1 +CCc1nc(C)cc(NCc2ccccc2OC)n1 +Nc1cc(F)ccc1C(=O)Nc1ccc(Br)cc1F +NC(=O)Nc1ccc(C(=O)Cn2nnc(-c3ccccc3)n2)cc1 +O=S(=O)(c1ccccc1)n1cccc1-c1n[nH]c2ncccc12 +CCOC(=O)c1sc(NC(=O)Cc2ccc(OC)cc2)nc1C +Nc1cc(F)cc(S(=O)(=O)N2CCC(O)CC2)c1 +O=c1n(Cc2nnc(Cc3ccccc3)o2)nc2ccccn12 +O=C(NC1CC1)c1cccc(-c2cc[nH]c(=O)c2)c1 +CCCn1nnnc1CSc1nc(C2CC2)n(-c2ccccc2)n1 +C#CCN1CCC(C(=O)N2CCCC2c2ccc3c(c2)OCO3)CC1 +O=C(c1cc(F)cc(Br)c1)N1CCN(CCO)CC1 +CCN(CC)C(=O)c1cccc2c(Cl)cccc12 +O=C(NCCNC(=O)c1nccn2ccnc12)c1ccc(Cl)cc1 +CCOC(=O)C1CCN(c2ccnc3c2c(=O)n(C)c(=O)n3C)CC1 +Cc1ccccc1C(C#N)CCC(=O)NCc1ccco1 +O=C1NC2(OC(=O)c3ccccc32)c2ccccc21 +CCCN(CCC)S(=O)(=O)c1cc(-c2ccc(=O)[nH]n2)ccc1C +COc1cccc(-c2cn3c4ccc(N)cc4nc3n2C)c1 +CC(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)NC(C)c1ccccc1 +CCn1c(CCNC(=O)C2COCCO2)nc2ccccc21 +COc1cccc(NC(=O)Cc2nc(Cc3ccccc3)n[nH]2)c1 +Cc1nc(CNC(=O)CCc2ccc(Br)c(C)c2)no1 +CNC(=O)c1cccc(NC(=O)Cc2cccc(OCC#N)c2)n1 +Nc1cccc(-n2c(-c3ccccc3)nc3cccnc32)c1 +COc1ccccc1CCOc1ccccc1CO +OC(CNCc1cccc(Oc2ccccc2)c1)c1ccco1 +CCn1nc(C)c2c(C(=O)NCc3ccc(C)o3)cc(C)nc21 +CCN(C1=Nc2cc(N)ccc2OC1)c1ccccc1 +CC(C)n1ncc2cc(NC(=O)COc3ccccc3F)cnc21 +CC(NC(=O)c1ccc(S(C)=O)cc1)C12CC3CC(CC(C3)C1)C2 +O=C(NCCNC(=O)c1ccccn1)c1ccoc1 +O=C(NCc1ccc(Cl)cc1)C1(c2cc(-c3ccco3)on2)CC1 +CC(C)N(CC1CC2C=CC1C2)C(=O)c1ccc(-n2ccnc2)nc1 +Cc1ccccc1CCNC(=O)c1nn(-c2ccccc2)c(C)cc1=O +CCn1cc(C(=O)Nc2ccc(C(N)=O)c(C)c2)cn1 +Cc1nc(CCC(=O)N2CCC(Sc3ccccc3C)CC2)n[nH]1 +COC(=O)c1ccc(OCC(=O)NC2CC2)c(OC)c1 +COc1ccc(S(=O)(=O)c2cc3cc(C)ccc3oc2=O)cc1 +CN(C)C(=O)Cn1cc(C(=O)N2CCc3ccccc3C2)nn1 +COCCNC(=O)COc1cc(C)c(Br)cc1C(C)C +CCC(=O)Nc1cccc(C(=O)N(C)C2CCC(C)CC2)c1 +CC(Cc1ccc(F)cc1)NCc1ccc(S(C)=O)cc1 +CC1CCC(NC(=O)COc2cccc(C(N)=O)c2)CC1 +CC(C)n1ncc2c(C(=O)NC(C)(C)C#N)cc(-c3ccccc3)nc21 +Cc1cccc(C(=O)NCC(=O)NCCCn2cccn2)c1 +CN(Cc1ccco1)C(=O)Cn1cc(C(F)(F)F)ccc1=O +COc1ccccc1C(O)CCCC(=O)NC(C)(C)C +CC(C(=O)Nc1cccc(N2CCCNC2=O)c1)c1cccs1 +COCCOCC(=O)NC1(c2cccc(Br)c2)CCC1 +CCn1c(SCC(=O)NC2CC2)nnc1-c1ccc(OC)cc1 +CSc1ccc(C(=O)N2CCCC(NC(C)=O)C2)cc1 +Cc1cccc(-n2ncc3c2CCCC3NC(=O)c2ccncc2)c1C +CCOC(=O)C1CCN(C(=O)c2cccnc2OCC)CC1 +O=C(Cc1ccc2c(c1)CCO2)Nc1ccnn1CC1CCOC1 +CC1CN(CC(=O)Nc2cc(C(C)C)no2)CC(C)O1 +CN(CC(=O)OCC(=O)Nc1sccc1C#N)c1ncccn1 +Cc1ccc(S(=O)(=O)CC(=O)NCC(F)(F)F)c(C)c1 +CC(OCC1CCCO1)C(=O)NCC1CCC(C)(C)CC1 +Cc1cccc(C(=O)NC2CCN(C(=O)CC(C)C)CC2)c1C +Cc1ccc(CN2CCC3OC(C(=O)N(C)C)CCC32)s1 +COc1ccc(C2=CCN(C(=O)Cn3nnc4ccccc43)CC2)cc1 +CC(C)N(CC1CC1)C(=O)c1cc(Br)cnc1N +N#CC(C(=O)c1csc(Cc2ccccc2)n1)c1ccccn1 +N#Cc1ccc(N2CCNC(=O)C2)cc1C(F)(F)F +CCCNC(=O)c1cnc(-c2ccncc2)nc1N +NC(=O)c1ccccc1NC(=O)C1CC(=O)N(C2CCOCC2)C1 +COC(=O)c1n[nH]c2ccc(NC(=O)c3n[nH]c4ccccc34)cc12 +NC(=O)c1ccccc1NC(=O)c1ccc2ncsc2c1 +CS(=O)(=O)N(Cc1ccc(C(=O)NC2CC2)cc1)C1CC1 +CC(CO)NC(=O)NC(C)C(=O)N1CCCCC1 +CC(=O)c1cccc(C)c1OCCN1CCOCC1 +COCC(=O)NC(c1ccccc1)c1ccc(C)cc1 +CC(C)NC(=O)CNc1ncnc2sccc12 +O=C(NC1CCc2c(ccc(=O)n2Cc2ccncc2)C1)c1ccoc1 +CC(C)c1csc(NC(=O)C2CCC(=O)NC2)n1 +NS(=O)(=O)CCNC(=O)c1cc2ccccc2o1 +COc1ccccc1NC(=O)COC(=O)c1ccc(F)cc1 +CN1CCN(C(=O)c2cc3c(=O)n(C)c(=O)n(C)c3s2)CC1 +O=C1COc2cccc(OCc3ccccc3)c2N1 +CC(C)CNC(=O)NCC(C)N1CCN(c2ccccc2)CC1 +CN(C)S(=O)(=O)c1ccc2c(c1)CCN2Cc1nc(C2CC2)no1 +CCCn1cc(NC(=O)NCC(C)(C)c2ccncc2)cn1 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccnc3ccccc23)cc1 +COCCN1CCC1c1cc(Nc2ncc(C)s2)nc(C)n1 +O=C(NCC1Cc2ccccc2O1)Nc1nncs1 +CN(Cc1cccc(C#N)c1)C(=O)CNC(=O)CC(C)(C)C +Cc1nc(C)n(CC(=O)NCCOc2cccc(F)c2)n1 +CC(=O)N1CCC(c2nccnc2Nc2ncccn2)CC1 +N#Cc1cccnc1-n1c(CO)nc2cc(N)ccc21 +CN(C(=O)c1c[nH]nc1-c1ccccc1F)c1cnn(C)c1 +CC(C)Nc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 +CCCN1C(=O)CCc2cc(NC(=O)CC)ccc21 +COC(=O)C1=C(C)Nc2nc(SC)[nH]c(=O)c2C1c1ccsc1 +CCN(C)C(=O)c1cccc(OC(=O)C(C)(C)c2ccccc2)c1 +CCOc1c(C)cc(-c2ccc(C(N)=O)c(N)n2)cc1C +COc1ccc(C(=O)Nc2c(C)ccc(N)c2C)cc1OC +CC(=O)N1CCc2cc(-c3nc(-c4cnn(C)c4)no3)ccc21 +CCc1ccc(CNC(=O)c2cnc3c(C)cccn3c2=O)cc1 +NC(=O)C1CCN(C(=O)CCCOc2ccccc2F)C1 +CCc1ccccc1NC(=O)CNC(=O)OCC(F)(F)F +O=C(OCCO)c1nc(-c2ccccc2)n(-c2ccccc2)n1 +Cc1nc(C)c(CC(=O)Nc2nc(C3CC3)cs2)c(=O)[nH]1 +O=C(c1cnn(-c2ccccc2)n1)N1CCOC2CCCCC21 +Cc1nnsc1C(=O)NCC1(c2ccccc2)CCOCC1 +CC(C)(CNC(=O)c1cccc2ccccc12)N1CCOCC1 +Cn1ccc(NC(=O)c2cc(C3CC3)nn2-c2ccccc2)n1 +CC(C)(NC(=O)Cc1cccs1)c1nc2c(c(C(N)=O)n1)OCO2 +CCNC(=O)CNC(=O)c1ccccc1SCC=C(C)C +Cc1nc2ccc(C(=O)OCC(=O)NCc3ccco3)cc2nc1C +N#Cc1nn(-c2ccc(F)c(F)c2F)c2c1CNCC2 +Cc1noc2nc(C(C)C)cc(C(=O)NCC(C)C)c12 +CCc1ccccc1-n1nnc(CO)c1C1CCC1 +NC(=O)c1cnc(COc2ccccc2Cl)nc1N +Cn1cccc1C(=O)OC1CCCC1n1cccn1 +COc1ccccc1CCC(=O)Nc1cccc(O)c1 +COc1ccc(NS(=O)(=O)c2ccccc2OC)cn1 +CCC(Sc1ccc(N)cc1)C(=O)NC1CCCC1 +Cc1cccc(NC(=O)COc2ccc(Br)cc2F)n1 +N#CCCN(CCC(F)(F)F)C(=O)Nc1cccnc1 +COCc1noc(CC2CN(c3nnc(C(C)(C)C)o3)CCO2)n1 +CCOc1ccc(Cn2c(=O)oc3ccc(N)cc32)cc1 +Cc1nc(N)nc(CCc2ccccc2)c1C(N)=O +Cc1nc(OCC(=O)Nc2cc(F)ccc2C)c2ccccc2n1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1cc(F)cc(F)c1 +CC(=O)c1ccccc1OCCN1CCNC(=O)C1 +Cc1ccc(-c2nnc(S(=O)Cc3ccc(F)cc3)n2C)cc1 +O=C(NCc1ccc(F)cc1)c1cccc2c1NCCC2 +CCC(C)C(=O)Cn1c(-c2cnccn2)noc1=O +COC(=O)CCNC(=O)COc1ccc(Br)cc1 +Cc1nc(SC(C)C(N)=O)c(C#N)cc1C(=O)Nc1ccccc1 +Cc1cc(C(=O)N2CC3CCC(C2)N(CC2CCC2)C3=O)no1 +CCC(c1ccccc1)N1CCN(C(=O)c2cnc(C)nc2C)CC1 +COc1ccc(OC)c(CNCc2nc3ccccc3s2)c1 +O=C(NCC(=O)N1CCCC1)NC1CCc2c(Cl)cccc21 +O=C(Cn1cncn1)Nc1ncc(C#CCO)s1 +COc1ccc(F)cc1NC(=O)N1CCN(Cc2cc(C)no2)CC1 +CCN(CC1CCCO1)C(=O)C1COc2ccc(F)cc2C1 +c1cc2[nH]nnc2cc1C1NCCc2cc3c(cc21)OCO3 +Cc1nc(C)c(C(=O)NCCCSc2ccc(F)cc2)s1 +Nc1cc(Cl)ccc1NS(=O)(=O)c1cccc(Cl)c1 +O=C(c1cc(C2CC2)n[nH]1)N1CCN(C(=O)c2ccccc2F)CC1 +COC(=O)C(NC(=O)c1cccc(F)c1)c1ccc(Cl)c(F)c1 +O=C(NCc1n[nH]c2c1CCC2)c1cn(Cc2ccccc2F)nn1 +COc1ccc(C(=O)Nc2ccc(C)c(C)c2)cc1NC(C)=O +O=C(Nc1ccccn1)Nc1ccn(Cc2ccccc2)n1 +Cn1nccc1C(=O)NC(Cc1ccsc1)c1cccnc1 +Cc1cccc(N2CCN(C(=O)C3CC(=O)N(C)C3)CC2)c1 +Cn1c(SCc2ccccc2)nnc1N1CCOCC1 +CCCNC(=O)CCCn1c2ccccc2c2cn[nH]c(=O)c21 +COc1ccc(N(Cc2ccco2)C(=O)Cc2ccc[nH]2)cc1F +Cn1ccnc1Cn1ccnc1-c1ccc(Br)cc1 +CC(c1ccccc1F)N(C)C(=O)c1ccnc(OC2CCC2)c1 +CCCNC(=O)C(N)c1cc(O)c(OC)c(OC)c1 +O=C(NCC1CCCc2ccccc21)c1ccco1 +CC1CC(OC(=O)c2ccc(-n3cccc3)cc2)C(=O)O1 +O=C(Nc1ccc(-n2cnnn2)cc1)c1ccc(Cl)cc1Cl +O=C(C(O)c1ccccc1)N1CCN(c2ncccn2)CC1 +CCN(Cc1c(F)cccc1F)C(=O)c1cc2ccccc2c(=O)[nH]1 +CCCCNC(=O)COC(=O)c1cn(C)c2ccccc12 +CCCN(Cc1cccnc1)C(=O)CCc1ccc(F)cc1F +Cc1ccc(OC(=O)C(C)NC(=O)c2ccco2)c(Cl)c1 +O=C(NCc1cc(Cl)c2c(c1)OCCCO2)c1cccnc1 +CCOC(=O)c1c(Cl)c2ccccc2oc1=O +CN(Cc1nnc2n1CCC2)C(=O)CCC(=O)c1ccc(F)cc1 +Cc1cc(C(=O)N2CCN(C(=O)c3cc(C)oc3C)CC2)n(C)n1 +COc1ccc(Br)cc1CNc1cccc(O)c1 +O=C1CN(C(=O)NCc2ccccc2-n2ccnc2)CCN1 +N#Cc1ccccc1OCC(=O)OCC(=O)NC1CC1 +CC(C)(C)n1nc(-c2ccc(F)cc2F)c(C#N)c1N +Cc1nc(C2CCCN(C(=O)COc3cccc(C(N)=O)c3)C2)no1 +Cc1nnc(SCc2nc3c([nH]2)CCCNC3=O)s1 +CC(=O)Nc1cccc(NC(=O)CNc2ccc3ccccc3c2)c1 +Cc1c[nH]c(CN2CCc3ccccc3C2)c(C)c1=O +O=C(Cc1ccccc1F)NCCNC(=O)c1ccnc2c1OCO2 +CC(C)(C)c1ccc(C(=O)Nc2ccccc2C(N)=O)cc1 +CCC(C(=O)OC(C)C)n1c(=O)oc2cc(CO)ccc21 +CC(=O)N(C)c1ccc(NCC(=O)Nc2cccc(C(N)=O)c2)cc1 +Cc1ccc2c(CNc3cccc(-n4nnnc4C)c3)cc(=O)oc2c1 +CN(C)C(=O)C1CC2CCN(Cc3nccs3)CC2O1 +O=C(CCNC(=O)c1ccccc1)Nc1nnc(C(F)F)s1 +COc1ccc(CCC(=O)Nc2ccccc2OC)cc1N +CN(Cc1ccc(OC(F)(F)F)cc1)C(=O)CNC(N)=O +NC(=O)Nc1ccc(NC(=O)CNC(=O)c2ccsc2)cc1 +CNC(=O)c1cc(NC(=O)N2CCOCC2C2CC2)ccc1F +CCc1onc(C)c1NC(=O)N(CC1CCCO1)C1CCC(C)CC1 +CCOc1c(OC)cccc1-c1nc(C)c(C#N)s1 +COc1cccc(C(=O)CNc2c(C)cc(C)cc2C)c1 +O=C(C1COc2ccccc2O1)N1CCCCC1c1nccs1 +CC(C(=O)NC(c1cccc(F)c1F)C(F)(F)F)n1cncn1 +CCc1n[nH]c(SC(C)C(=O)c2ccc3c(c2)CCC(=O)N3)n1 +Cc1nc(SCC(=O)N(C)CC(F)(F)F)c2ccccc2n1 +O=C(Cc1ccsc1)NC1CCc2cc(F)ccc21 +COc1ccc(C(O)C2CCCCO2)c(Br)c1 +CCc1ccc2oc(-c3ccc(N)cc3O)nc2c1 +COc1ccc(-c2nc(CN)cc(=O)[nH]2)c(OC)c1 +O=C1CN(C(=O)c2cc3ccccc3[nH]2)CCN1CCc1ccccc1 +Cc1ccc(Cl)cc1NC(=O)c1nc2ncccn2n1 +COCCN(C(=O)c1ccc(-n2cnnn2)cc1)C1CCCC1 +O=c1c(N2CCc3ccccc32)csc2ccc(F)cc12 +CCCCS(=O)(=O)NC1CCCc2occc21 +O=C(Nc1ccc(Br)cc1)N1CCCCC1 +CN(C)c1nccnc1-c1ccc2c(c1)OC(F)(F)O2 +CN1C(=O)C2CN(CCCc3ccccc3)CCN2C(=O)C1CO +Cc1noc(C)c1S(=O)(=O)N(C)CCOc1cccc(Cl)c1 +COCCNC(=O)c1cc(S(=O)(=O)NC(C)C)ccc1Cl +C=CCn1c(N)nnc1SCc1ccc(C(=O)N2CCCC2)cc1 +O=C1CC(C(=O)NCCCn2ccnc2)C2(CCCC2)O1 +COC(C)(C)c1noc(Cc2cn(C)c3ccccc23)n1 +CCOCC1CC2(COCCN2C(=O)c2cccc(OC)c2)CO1 +CC(=O)NCCCNC(=O)c1cccn(Cc2ccccc2)c1=O +Cc1cccc(-c2nc(CN3CCN(C(=O)N(C)C)CC3)no2)c1 +CC1CCCCC1OCCNC(=O)c1ccc2c(c1)OCC(=O)N2 +Cc1cccc(S(=O)(=O)C(C)C(=O)NCC(C)C)c1 +Cn1cnc(-c2ccc(F)cc2)c1NC(=O)c1ccc2c(c1)OCO2 +COc1ccc(N)cc1NC(=O)c1cc(C)ccc1O +CCCCCC(=O)N(C)Cc1csc(C#CCO)c1 +O=C(NCCCN1CCOCC1)c1ccc2c(c1)Cc1ccccc1-2 +N#Cc1ccc(NC(=O)N2CCCC2c2nnc3ccccn23)cc1 +Cc1cc(Br)ccc1-n1nc(C)c(C#N)c1C +CN(CCc1ccccc1)C(=O)Nc1cnn(-c2ccccc2F)c1 +COCC(C)OC(=O)c1cc(N2CCCC2=O)cc(C(F)(F)F)c1 +Cc1nn(C)c2ncc(CSc3nccc(C(F)(F)F)n3)cc12 +COC(=O)C1=c2c(=O)n(C)c(=O)n(C)c2=NC(=O)C1 +CC(Sc1nc(N)c(C#N)cc1C#N)c1cn(-c2ccccc2)nn1 +Cc1ccccc1C1CN(C(=O)c2cccc(-c3ccoc3)c2)CCO1 +COc1cccc(CC(=O)NCc2cnn(-c3ccccc3)c2)c1 +Cc1nc2ccc(N)cn2c1C(=O)N1CCOCC1 +CCCc1[nH]nc(C(=O)NC(C)CCC(C)C)c1N +Cc1cc(CNC(=O)c2ccc3c(c2)OCO3)c(C)o1 +CCCn1cc(NCc2c(C)nn(Cc3ccccc3)c2C)cn1 +O=S(=O)(c1ccc(F)cc1)N1CCN(CCc2ccccn2)CC1 +Cc1ccc(C)c(C(=O)Nc2cnn(-c3ncc(N(C)C)cn3)c2)c1 +COc1cccc(C(=O)NC(C)c2ccccc2)c1O +Cc1nc(-c2ccc(NC(=O)NCCN3CCOCC3)cc2)no1 +Cc1ccc(C(c2ccccc2)C(CC#N)CC#N)cc1 +COC(=O)c1c(NC(=O)C2CC3CCC2C3)sc2c1CCC2 +C=CCNC(=O)Nc1ccc(CN2CCOC2=O)cc1 +COc1cc(C2(C(=O)NCCc3ncc(C)s3)CC2)ccc1C +Cc1occc1C(=O)N(C)c1cccc2ccccc12 +CNC(=O)C1CCN(C(=O)c2ccccc2Cl)CC1 +N#Cc1nc2ccc(F)c(F)c2n1-c1ccncc1 +CC1CC1C(=O)Nc1ccccc1SCCC#N +COCCOCC(=O)Nc1cc2c(cc1Cl)OCCCO2 +Cn1cnc(CNC(=O)c2ccc(Br)cc2O)n1 +N#Cc1ccc(NC(=O)c2cc(Cl)ccc2F)nc1 +CN(Cc1nc2c(s1)CCCC2)C(=O)NCc1ncn(C)n1 +CCC(CC#N)N1CCN(c2ccc(Cl)cc2)CC1 +CC(C)C(=O)N1Cc2ccc(C(O)Cc3ccccc3)cc2C1 +NC(=O)C1CCCN1C(=O)C1CC1c1ccc(F)cc1 +CC(NC(=O)Nc1ccc2c(c1)COC2)c1cccc(-n2cccn2)c1 +CC(NC(=O)N(CCO)C1CC1)c1cc2cc(Cl)ccc2o1 +Cc1ccc(CNC(=O)NCCc2ccccn2)cc1 +Cn1cc(CNC(=O)Nc2ncc(Cc3cccc(F)c3)s2)cn1 +N#CC(C(=O)COc1ccccc1)c1nnc2n1CCCCC2 +COc1cccc(C(=O)NC(C#N)c2cccc(Cl)c2)c1 +Cc1noc(-c2csc(Cc3ccccc3)n2)n1 +CC1(O)CCN(C(=O)CCc2ccncc2)CC1O +N#Cc1cccc(C(=O)N2CCCCC2CCO)c1 +CCn1cnnc1CNC(=O)N1CC(C)OC(c2ccsc2)C1 +Cc1nc2ccccc2n1CCCNC(=O)N1CCOC(C)(C)C1 +O=C(CSc1nnnn1-c1ccccc1)N(C1CCCC1)C1CC1 +COCCNC(=O)c1cn(Cc2ccccc2)nc1-c1cccnc1 +CC(C)c1cc(C(=O)Nc2nc(-c3c[nH]c(C(N)=O)c3)cs2)n[nH]1 +Fc1cncc(C2NCCc3cccc(OC(F)F)c32)c1 +O=S(=O)(c1ccccc1)N(Cc1ccsc1)Cc1ccco1 +Cn1cc(CNC(=O)c2ccc(NC3CC3)nc2)cn1 +CCc1ccc(CCNC(=O)NCc2nnc3ccccn23)cc1 +O=C(CN1CCN(c2ccc(O)cc2)CC1)NC(C1CC1)C1CC1 +COc1ccc(C(=O)N2CCN=C2Nc2nc(C)cc(C)n2)cc1 +Cn1nccc1C(=O)Nc1ccc(OCC#N)cc1 +CCOC1CCCN(c2ccc(N)c(OC)n2)C1 +COCCn1cc(NC(=O)N(C)CCC(C)O)cn1 +O=C1COc2ccc(O)cc2N1Cc1cccc2ccccc12 +CCOc1ccccc1NC(=O)c1cnc2ncnn2c1C +CNC(=O)c1cccc(NC(=O)c2cccnc2OCC(F)F)n1 +CC(C)n1cnc(-c2nc(C(=O)N3CCOCC3)c3ccccn23)c1 +CC(=O)Nc1ccc(NC(=O)CNc2ccc(C)c(C)c2)cc1 +Cn1cnc(CNC(=O)Nc2ccc(CCCc3ccccc3)cc2)n1 +Cc1ccc(OCC(=O)NCC(F)(F)F)c(Br)c1 +Cc1cc(OCC(=O)NC(C)(C#N)C(C)C)nnc1C +CCOC(=O)c1cc(C)n(N(C)c2cc(C(F)(F)F)ccn2)c1C +O=C(Nc1ccc(-n2ccnn2)cc1)c1scnc1C1CC1 +CC(=O)OCCNC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +CN(C)C(=O)c1ccccc1NC(=O)c1ccc(OCC(F)F)nc1 +COc1ccc2c(cnn2CCN2CCOCC2)c1 +CNC(=O)Nc1c[nH]c2c(Cl)cccc2c1=O +CNC(=O)c1onc(-c2cccc(Br)c2)c1N +O=C(Nc1cccc(Br)c1)c1cc(-c2cccnc2)[nH]n1 +COc1ccc(Cn2nc(C)c(Br)c2C)cc1F +Cc1cc(C)c(C(O)CNS(C)(=O)=O)c(C)c1 +COc1ccc(CCNc2c(C)nn(C)c2C)cc1 +COC(=O)c1c(C)[nH]c(C(=O)OCC(=O)N2CCC(C)CC2)c1C +O=S(=O)(c1ccc2c(c1)CCC2)N1CCC(O)CC1 +COc1ccc(S(=O)(=O)NCC(C)O)cc1C +Cc1cc(C(N)=O)c(NC(=O)CCCc2cc(F)ccc2F)s1 +CCC1(CNC(=O)Cc2ccc(F)cc2F)CC1 +CCSc1cc(C(=O)NC(C)(CC)C(=O)OC)ccn1 +Cc1cc(C)c(S(=O)(=O)NCC(C)C)cc1C +COc1cc(=O)n(CCOc2ccccc2F)cc1Br +Cc1nn(C)c2nc(N3CCCCC3c3cccnc3)sc12 +Cc1ccc(NCc2nc(C(F)(F)F)cc(=O)[nH]2)c(Cl)c1 +CC(OC(=O)C(C)(C)C)c1ccc2c(c1)OCCO2 +Nc1nnc(SCc2cc(Br)ccc2F)n1C1CC1 +O=C(NCc1cccc(OC(F)F)c1)c1c(F)cccc1F +C=CCNc1ccccc1Oc1ncccc1C#N +Nc1c(-c2cccc(Cl)c2)noc1C(=O)NC1CCCC1 +O=C(c1ccncc1)N(CCc1ccccc1)Cc1ccncc1 +COc1cc(S(=O)(=O)NCc2cccs2)c(OC)cc1C +COc1ccc(CCNC(=O)CN2CCCC3(C2)OCCO3)cc1 +CCc1ccc(CNC(=O)COC(=O)c2sccc2C)cc1 +CCCc1ccc(-c2nccn2CCc2nc(C)cc(=O)[nH]2)o1 +CCN(CC)C(=O)N(Cc1cc(OC)ccc1OC)c1cnn(C)c1 +O=C(NC(c1ccccc1)c1ccccn1)C1Cc2ccccc2O1 +O=C(Nc1c[nH]c(=O)[nH]c1=O)c1ccc(N2CCCCC2)nn1 +Cc1nn2cc(C(=O)NCCCC(=O)Nc3ccccc3)nc2s1 +CCNC(=O)c1cc(-c2ccc(C)cc2)nc(N)n1 +Cc1ncc(CNC(=O)CCC(=O)c2ccc(Cl)cc2)s1 +N#CC(CCC(=O)NCC1CCCO1)c1cccs1 +Nc1nc(N)nc(COC(=O)c2cc(F)ccc2F)n1 +CN1C(=O)C2(CC2C(=O)NCc2cccnc2)c2ccccc21 +COC(=O)N(C)c1ccc(NC(=O)C2CCCO2)cc1 +COC(=O)c1ccsc1NC(=O)CSc1nc2ccccc2[nH]1 +C#CC(C)(CC)NS(=O)(=O)c1cc(F)ccc1OC +CCOc1ccc(OCC)c(NC(=O)c2ccc3[nH]nnc3c2)c1 +Cc1cccnc1C(C)NC(=O)c1cccc2c1NCCC2 +CCC(C)(C)NC(=O)C(C)Sc1nnnn1C1CCCCC1 +Cc1cccc(OCCCNC(=O)c2cccnc2-n2cncn2)c1 +CC(C)(C)c1noc(CCC(=O)NC2CCCCNC2=O)n1 +CC(C)CCCCNC(=O)Cc1cn2ccsc2n1 +Cn1c(C(=O)N2CCCC2)cc2c(=O)n3ccccc3nc21 +N#Cc1cccc(S(=O)(=O)NCCCN2CCOCC2)c1 +CCC(CCO)NC(=O)Nc1cc(OC)c(Cl)cc1OC +CCSc1nnc(SCC(F)(F)F)s1 +CC(C)(C)C(C#N)NC(=O)COc1cccc(C(N)=O)c1 +CCOC(=O)CSc1nc(=O)n2cc(C)ccc2n1 +Cn1c(SCC(=O)N2CCOCC2)nnc1-c1ccc(F)cc1 +O=C(Cc1ccccc1Cl)NCc1ccc(Cn2ccnc2)cc1 +CCOc1ccc(CN(C)C(=O)c2ccccc2OC)cc1 +CC(C)Cc1cc(-c2nnc3sc(C4CC4)nn23)n(C)n1 +CC(Oc1ccccc1C#N)C(=O)N(C)C1(C#N)CCCCC1 +CC(O)CN1CCN(C(=O)c2cnc(-c3ncccn3)s2)CC1 +CC1CCN(C(=O)c2cn(-c3ccc(Br)cc3)nn2)CC1 +CCc1onc(C)c1NC(=O)CCCOc1ccccc1C +COc1c(Cl)cccc1NC(=O)c1ccc(NC(C)=O)cc1 +O=C(OCCO)c1nc(-c2cccs2)n(-c2ccccc2)n1 +CCN(Cc1ccccc1)C(=O)C1CC(=O)N(C2CCCCC2)C1 +Cc1ccc(N2C(=O)c3[nH]nc(C)c3C2c2ccccn2)cc1 +c1nc(C2CC2)c(-c2nc(C3CCOC3)no2)s1 +O=C(NCCNc1ncccn1)N1CCCC1c1ccc(F)cc1 +Cc1ccc2c(c1)C(=O)C(=O)N2Cc1ccccc1C +Cc1cc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)on1 +CCN1C(=O)COc2ccc(C(=O)NCC(C)C)cc21 +Cc1cc(C(=O)Nc2nnc(Cc3ccc(C(C)C)cc3)o2)on1 +O=C(CNC(=O)NCc1ccccc1)Nc1ccc(Cl)cc1 +Cc1nn(CCOc2ccc(Br)cc2)c(=O)c(C#N)c1C +Cc1ccsc1C(=O)Nc1cc(-c2nnc(C3CC3)o2)sc1C +Cc1ccccc1-c1cc(C(=O)N(C)C)c2cnn(C(C)C)c2n1 +O=C(NCC(F)(F)F)N1CCC(OCc2ccccc2)CC1 +OCc1c(Cl)cc(Br)cc1Cl +CC(=O)c1cccc(NC(=O)c2ccc(F)c(F)c2F)c1 +CCc1nc(NCc2ccc3c(c2)OCO3)c(N)c(OC)n1 +CCOc1ccc(F)c(C(=O)N2CCCC(CCC(N)=O)C2)c1F +CCCNC(=O)c1ccc(C2Nc3ccccc3S(=O)(=O)N2)cc1 +CC(C)n1nccc1NC(=O)CCC(=O)c1ccc2c(c1)OCCO2 +Cc1ccc(Cc2nnc(SCC(=O)Nc3ccccc3)o2)cc1 +O=C1CCc2cc(C(=O)NCC3CN4CCCCC4CO3)ccc2N1 +Cc1cccc(Cn2cccc2CNC(=O)NC(C)C)c1 +CC1c2cccn2CCN1C(=O)CCc1nc2ccccc2[nH]c1=O +CC(CC(O)c1ccccc1)NC(=O)c1cccc(-c2ccoc2)c1 +O=C(c1ccnc2ccccc12)N1CCc2cc(F)ccc2C1 +O=C(Nc1ccc(CN2CCCC2=O)cc1)c1cccnc1 +Cc1cc(C)cc(N(C)S(=O)(=O)c2ccc3c(c2)NC(=O)CO3)c1 +Cc1nnc(SCC(=O)NC(C)Cc2ccccc2C)s1 +CCOc1ccccc1CNC(=O)C1Cc2ccccc2CN1C +Cc1ccc(Cl)cc1OCc1nnc2n1CCCCC2 +CC(=O)c1sc2ncn(Cc3ccco3)c(=O)c2c1C +O=C(NC1CCCC1)c1ccc2cccc(O)c2n1 +Cc1ccc(NC(=O)CNC(=O)OC(C)(C)C)c(Cl)c1 +COc1ccc2[nH]cc(C(=O)NCCCC(=O)NC(C)C)c2n1 +N#Cc1ccc(-c2ccco2)nc1SCC(=O)NC1CCCCC1 +O=S1(=O)CCCN1CCc1ccc2c(c1)OCO2 +Cn1ccnc1CSc1nccc(C(F)(F)F)n1 +CN(C)C(=O)CCc1ccc(N2CCCC2)c(N)c1 +CCC(C)C(=O)Nc1ccc2[nH]c(C3CCC3)nc2c1 +CN(C(=O)c1ccccc1F)C(C#N)c1ccccc1 +COC(=O)CCN1CCN(c2nccc(C)n2)C(C)C1 +CCOc1ccc(-c2[nH]ncc2C(=O)N2CCOCC2)cc1Cl +CCN1CCOC(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)C1 +COCCN(C(=O)Cc1c(Cl)cccc1Cl)C(C)C(N)=O +Cc1cc(NC(=O)CCOC(C)CC(C)C)ccn1 +O=C(NCC(=O)N(C1CC1)C1CCCc2ccccc21)C1CC1 +O=S(=O)(c1cc(F)ccc1F)N1CCCCC1C1OCCO1 +Cn1nnc2cc(COC(=O)CCCc3ccccc3)ccc21 +CS(=O)(=O)N1CCC(NC(=O)N2CCc3cc(F)ccc32)CC1 +O=C(Cn1cccn1)N1CCN(C(=O)c2cnn3ccccc23)CC1 +Cc1occc1CN(C)C(=O)NCc1ccc(S(N)(=O)=O)cc1 +C=CCOCC1c2nnn(CC)c2CCN1C(=O)Cc1ccccn1 +Cc1ccc(S(=O)(=O)NC(C#N)C(C)C)cc1C +O=C(NCC(F)(F)F)C1CN(S(=O)(=O)C2CC2)C1 +O=C(COc1ccc2c(c1)OCCO2)c1c(O)cc(O)cc1O +Cc1cc(C)c(NC(=O)CNC(=O)NC(C)c2nncn2C)c(C)c1 +COC(=O)C(C)Oc1ccccc1-c1csnn1 +COCc1nc(CCOc2ccc(C)cc2)sc1CO +Cc1ccc(-n2ncc3c(N4CCCC4)ncnc32)c(C)c1 +Cc1nc(N2CCCC2C(N)=O)c2cc(-c3ccccc3)sc2n1 +CN(Cc1cccc2c1OCO2)Cc1nc2ccccc2n1C +CNc1nnc(-c2cc(-c3cccnc3)oc2C(C)C)s1 +CN(Cc1cccc(C(N)=O)c1)C(c1ccccc1)C(F)(F)F +Cc1ccccc1-n1nc(C(=O)Nc2ccccc2F)nc1C +CCc1ccc2nc(C)cc(C(=O)N3CCCC3)c2c1 +CNc1ncc(C(=O)NC2CC(C)OC(C)C2)s1 +CCC(=O)Nc1ccc(NCC(=O)NC(C)c2ccccc2)cc1 +CCCCNC(=O)Nc1nnc(Cc2ccccc2)s1 +Cc1ccc(-n2nnnc2SCN2CCCCC2=O)c(C)c1 +CC(C)OCCC(=O)N(C)C1CCc2ccccc2C1 +Cc1ccsc1CN(C)C(=O)c1ccc2c(c1)OCO2 +CN(CC1CCCCC1O)C(=O)NCC1Cc2ccccc2O1 +O=C(Nc1ccc(F)cc1)c1cnc(N2CCOCC2)nc1 +O=C(CN(CCO)c1ccccc1)N1CCCCC1 +CC(C)CC(=O)N1CCN(c2nccn2-c2cccc(Cl)c2)CC1 +O=C(Nc1ccccc1-n1cccc1)C1CCCC1 +COCc1nnc(SCc2cccc(OC)c2)n1-c1ccccc1 +O=C1CN(C(=O)CCC(=O)c2ccc3c(c2)OCCO3)CCN1 +N#CCOC(=O)c1cc(Cl)c2c(c1)OCCO2 +CC(Cc1ccco1)NC(=O)NCC(C)(O)c1ccsc1 +Cc1cc(S(=O)(=O)NCc2ccccc2-n2ccnc2)ccc1F +O=C(Cn1cnnn1)Nc1nnc(-c2ccsc2)s1 +O=C(Nc1cccc(-c2nnnn2C2CC2)c1)N1CCCC1CO +COc1cccc(CCC(=O)NCc2cccnc2OC)c1 +COc1ccccc1C(C)NC(=O)COc1ccc(C)cn1 +c1ccc(CSc2ccc(-n3ccnc3)nn2)nc1 +Cc1ccc(-c2noc(CSc3ncccn3)n2)cc1 +Cc1ccccc1CS(=O)(=O)c1ccc(O)cc1 +COCCNC(=O)c1ccc(-c2ccnc3c2ccn3C)o1 +CNC(=O)Cc1csc(-c2cccc(OC)c2OC)n1 +Cc1ccccc1CS(=O)(=O)N1CCCC1C(=O)N(C)C +CN(C)S(=O)(=O)c1ccc2c(c1)N(C(=O)CC1CCCO1)CC2 +Oc1ccc(-c2nc3cnccn3c2NC2CCCC2)cc1 +Cc1ccc(-c2nnc(SCC(=O)N3CCCCC3)n2C)cc1 +O=C(C1COCCO1)N(CCc1cccc(F)c1)C1CC1 +Cc1sc2[nH]c(C(C)N3CCc4ccccc43)nc(=O)c2c1C +COc1ccc(CCNC(=O)c2cc3c([nH]c2=O)CCC3)cc1 +CCc1cccc(CC)c1NC(=O)c1cnc(C2CC2)nc1N +CCCCOc1cccc(NC(=O)c2csc(C)n2)c1 +CCn1c(SCC(=O)NCC(C)C)nnc1-c1ccccc1C +O=C(c1cc(-c2ccc(F)cc2)c[nH]1)N1CCC2(CC1)OCCO2 +Cc1ncsc1COC(=O)c1cccc2c1ccn2C +N#CCCNS(=O)(=O)c1ccc(C(=O)NC2CC2)cc1 +COc1ccc(-c2nnn(CCOc3ccc(F)cc3)n2)cc1OC +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)c2ccccc2)c1C +CC(NC(=O)c1cncn1-c1ccccc1)c1ccc2c(c1)OCCO2 +O=C(NCc1ccc2c(c1)OCO2)c1cccc2c1OCCCO2 +CN(CC(=O)NC(C)(C)C)C(=O)c1cccc(Oc2ccccc2)c1 +CC(C)(CCC#N)CNc1ccc(Cn2cccn2)cc1 +Cn1cc(S(=O)(=O)NC2CCc3cc(F)ccc32)cc1C(N)=O +Cc1noc(C)c1CC(=O)N(Cc1ccccc1)CC1CCCO1 +COc1cc(OC)cc(C(=O)N2CCOc3cc(N)ccc32)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)NC(C)C(=O)OC(C)(C)C +CC1CCCCN1S(=O)(=O)N1CCC(C(N)=O)CC1 +Cn1cnc(CNC(=O)N2CCc3ccc(Cl)cc32)n1 +Cc1ccc(C(=O)Cn2c(C)c(C)sc2=O)cc1 +O=C(c1ccc(-n2cccc2)cc1)N1CCC(Oc2ccccn2)CC1 +COc1ccc(-n2c(Cc3ccccc3F)n[nH]c2=O)cc1 +CC(C)c1cc(C(=O)N2CC(c3ccccn3)C2)no1 +CCc1noc(CC)c1CC(=O)NCc1cc2ccccc2[nH]1 +Cc1ccc(NC(=O)Cc2nc3cc(N)ccc3o2)cc1C +Cc1cc(C(=O)NCC(=O)N2CCCC2c2cccc(F)c2)c(C)o1 +O=C(Nc1ccccc1C(=O)NCc1ccc[nH]1)c1ccccc1 +CC(C)(CNC(=O)COc1ccc(F)cc1)N1CCOCC1 +Cc1nc2cc3c(cc2n1CC(F)(F)F)OCCO3 +COc1ccc(C(O)CCNc2cccc(F)c2)cc1N +CC(C)(C)n1nnnc1SCC(=O)c1ccc(O)cc1 +Cc1ccc(C(=O)Nc2cccc(OCCc3ccccc3)c2)c(=O)[nH]1 +O=C(c1csc2ccccc12)N1CCCC(CO)C1 +N#Cc1ccc(OCCOC(=O)c2cnn(-c3ccccc3)c2)cc1 +COc1ccccc1C(NS(=O)(=O)N(C)C(C)C)c1ccccn1 +CCc1nc(NC(=O)NCCc2cscn2)nn1C +O=C(CSc1ccc(-c2ccccn2)nn1)N1CCOCC1 +CCS(=O)(=O)c1ccc(NC(=O)c2cc(F)ccc2C)cc1 +Nc1ccccc1S(=O)(=O)Nc1ncccn1 +CCCn1ccc(C(=O)NC(C)c2ccc(-n3cccc3)cc2)n1 +CS(=O)(=O)c1ccsc1NC(=O)CCSc1ccccn1 +CCCn1cc(NC(=O)N2CCOCC2C2CC2)cn1 +CCC(=O)Nc1ccc(NC(=O)c2cccc3ccc(C)nc23)cc1 +Cn1ccnc1SCC(=O)Nc1cccc(Cl)c1Cl +Cc1ccc(-c2ncc(C(=O)N3Cc4ccccc4C3)c(=O)[nH]2)cc1 +O=S(=O)(Cc1c(F)cccc1Cl)NCc1ccccn1 +CCc1cc(=O)oc2cc(OC(C)C(C)=O)ccc12 +O=C(CN1CCOCC1)Nc1ccc(OCCc2ccccc2)cc1 +CCc1c(CO)nnn1Cc1ccc(Br)cc1 +O=C(Nc1ccccn1)c1cc2c(=O)n3ccccc3nc2s1 +CCOCCC(=O)N(CC)c1cccc2ccccc12 +COc1cc(C2CC(NC(C)=O)CC(CC(C)C)O2)ccc1F +CCOc1ccc(CNS(N)(=O)=O)cc1OC +COc1ccc(-n2nnc(-c3ccc(F)cc3)c2N)cc1 +CCOc1cc(-c2nc(C)c(C#N)s2)ccc1OC +CCCCN(CCO)S(=O)(=O)C1CCOCC1 +Oc1cccc(CN2CCN(c3ncccc3C(F)(F)F)CC2)c1 +CS(=O)(=O)N1CCC(S(=O)(=O)c2ccc(F)cc2)CC1 +Cc1ccc(CC(=O)N(C)Cc2ccc(F)c(F)c2)cn1 +CC(C)(C)NC(=O)CNC(=O)NCc1ccc(Cn2ccnc2)cc1 +Cn1ccc(NC(=O)CC2OC(=O)c3ccccc32)n1 +O=C(Cc1ccccc1Cl)NCc1nnc(-c2cccs2)o1 +CCOc1ccc(C(=O)Nc2ccccc2N2CCOCC2)cc1 +O=C(Cn1cc(NC(=O)Nc2cccnc2)cn1)NC1CCCC1 +CCOC(=O)c1cc2nc(NCCOC)sc2cc1Cl +O=C1CCc2cc(C(=O)OCc3ccccn3)ccc2N1 +COc1ccccc1C=Cc1nc(C#N)c(N2CCOCC2)o1 +COc1ccc(CNC(=O)Nc2ccc3c(c2)C(=O)NCC3)cc1 +CC(C)COC(=O)N1CCCN(CC(C#N)CCC#N)CC1 +CN(C)C(=O)CN(C)c1ncc(S(N)(=O)=O)s1 +Cc1nnc(-c2ccc(NC(=O)c3ccc(OCC4CC4)cc3)cc2)o1 +CSc1cccc(NC(=O)c2cn3c4c(cccc4c2=O)CC3)c1 +CC(Nc1cccc2cnccc12)c1ccsc1 +O=C(NCc1ccccc1COCC1CC1)c1ccn2ccsc12 +CCc1ccc(OCc2nc(C)c(CCO)c(=O)[nH]2)cc1 +COc1ccc2[nH]cc(CCNC(=O)Cc3n[nH]c4ccccc34)c2c1 +COC(=O)C(C)NC(=O)c1ccc2c(c1)CCCC2 +Cc1ccc(=O)n(CC(=O)Nc2cc(N3CCCC3)ncn2)n1 +Cc1cc(C(F)(F)F)cc(=O)n1CCCc1cccnc1 +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(OC)cc2)c1C +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1cccc2cn[nH]c12 +COc1cc(C)c(C(=O)CCC(=O)NC(C)C)cc1C +Cc1cc(C)c(NCC(O)c2ccc(F)c(N)c2)c(C)c1 +COc1ccc2nc(CNC(=O)c3c(C)cc(C)[nH]c3=O)[nH]c2c1 +Cc1ccc(C(=O)NCCn2nc(C(F)(F)F)n(C)c2=O)cc1 +NC(=O)Nc1cccc(C(=O)N2CCCC2c2nc3ccccc3[nH]2)c1 +CCCN(Cc1ccccc1)S(=O)(=O)c1cccc(C#N)c1 +COc1cc(O)c(CCO)c2c1C(=O)CC(C)O2 +Cc1ccc(C)c(OC2CCN(S(N)(=O)=O)CC2)c1 +CC(C)OC(=O)CSc1nnc(C(C)(C)C)n1N +O=C(NCCC1CCCO1)C1CCCN1C(=O)OCC(F)(F)F +O=C(OC1CCC2(CC1)OCCO2)c1cccc(F)c1 +CC1CN(C(=O)Cn2c(=O)oc3cc(Cl)ccc32)CC(C)O1 +Cc1nn2c(=O)cc(CN(C)Cc3ccccc3)nc2s1 +Cc1cccc2c(NCCCC(=O)NC3CC3)ncnc12 +CCOc1cc(NCC2COc3ccccc3O2)ncn1 +O=C(NCC1(c2ccccc2)CCC1)c1cc(-c2ccco2)[nH]n1 +CC(C)(C)CC(=O)Nc1ccc(C(=O)N2CCCC2)cc1 +Fc1ccc(-c2cc(N3CCOCC3)nc(-c3cccnc3)n2)cc1 +CCC1C(=O)NCCN1C(=O)c1cccc(-n2cnnn2)c1 +Cc1ccc(NC(=O)c2ccn(C)c(=O)c2)c(OCC(=O)N(C)C)c1 +CCOc1ccccc1-c1ccc(C#N)c(=O)n1CC +CC1CCCCN1C(=O)c1ccc2c(c1)OCCO2 +Cc1cc(C(=O)CSc2nc(N)cc(=O)[nH]2)c(C)n1C +CC(C)(C)c1ccc(C(=O)N2CCOCC2C2CC2)cc1 +Cc1ccc(C(=O)N2CCN(Cc3ccc4c(c3)CCO4)CC2)o1 +N#Cc1ccc(SCC(=O)Nc2cc(F)c(F)c(F)c2)cc1 +COc1ccc(CNC(=O)Nc2ccc(OC)c(C)c2)cn1 +CC1Cc2ccccc2N1C(=O)COC(=O)c1n[nH]c2ccccc12 +COc1cc(CCNC(=O)c2cc(OC)c(OC)cc2C)ccc1C +OCc1nc(-c2sccc2Br)cs1 +Cc1cc(C(=O)Nc2cccc(-c3nnnn3C)c2)c(C)n1C1CC1 +CC1COCC(C)N1Cc1ccc(S(=O)(=O)N2CCCC2)o1 +COC1CCCC(OC(=O)C2CCCN(C(N)=O)C2)C1 +COc1ccc(C(=O)Nc2cnccc2C(N)=O)cc1-c1ccccc1 +CC(=O)N1CCOC2CN(C(=O)NCc3ccccc3)CCC2C1 +COCCCNC(=O)c1ccccc1-c1ccccc1 +COC(=O)c1sc(S(C)=O)c2c1CC(C)(C)CC2=O +OCCc1cnn(Cc2ccc(Cl)c3cccnc23)c1 +CC1(CNC(=O)Nc2cc(N3CCCC3=O)ccc2F)CCCC1 +O=C(CO)N1CCc2ncnc(NCCn3cccn3)c2CC1 +CC(Oc1ccccc1N)C(=O)Nc1cccc(Cl)c1 +CCCC1CCC(NC(=O)NCCc2nnc3n2CCCCC3)CC1 +O=C(OCc1ccccn1)c1csc(Cc2ccccc2)n1 +COc1ccc(CC2COc3cc(O)ccc3C2=O)cc1 +COc1cc(NC(=O)CN(C)c2ccc(F)cc2)cc(OC)c1OC +Cc1[nH]c(SCCCC#N)nc1Cc1ccccc1 +CC(=O)Nc1cccc(COC(=O)c2cn(C)nc2C(C)(C)C)c1 +CC(=O)NCCNC(=O)N1CCC(C)C2CCCCC21 +CCN(Cc1cccc(NCC(=O)Nc2cc(C)on2)c1)C(C)=O +CCOC(=O)c1c(NC(=O)COc2ccccc2)sc2c1CCC2 +O=C(Nc1ccc(N2CCCC2=O)c(F)c1)c1ccncc1 +Cc1ncc(N)cc1C(=O)NCc1cccc(F)c1 +CC(C)CC(=O)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +CCCNC(=O)c1nn(-c2ccc(F)cc2)c2c(=O)n(C)cnc12 +COc1cccc(C2CCCN2C(=O)Cc2ccc[nH]2)c1 +COC(=O)CCN1CCN(CC(=O)OC)C(C)C1 +CNC(=O)c1ccccc1NC(=O)c1cccc(OCC(C)C)c1 +Cc1nn(CC(=O)Nc2nccs2)c(C)c1N +CC(C)C(C)NC(=O)C1CCN(S(=O)(=O)C2CCCCC2)CC1 +CSc1cnn(-c2ccccc2)c1NC(=O)c1cc(C#N)cs1 +Cc1cc(C)cc(CNC(C)C(=O)NC(C)(C)C)c1 +CC(C)(C)C(=O)Nc1ncc(F)cc1CCCO +COCc1cc(N(C)Cc2cnccn2)nc(C(C)(C)C)n1 +CCS(=O)(=O)NC(C)c1cc(OC)ccc1OC +O=C(CCn1nnc2ccccc2c1=O)Nc1n[nH]c2ccccc12 +Cc1ccncc1NC(=O)N(Cc1cccs1)CC1CCCO1 +Cn1ccnc1C(=O)c1ccc2c(c1)OCCCO2 +CCn1cnnc1CN(C)c1ncc2c(n1)CCN2c1ccccc1 +CC(C)CCn1c(=O)c2ccccc2n2c(SCCO)nnc12 +Cc1ccc(C(C)NC(C)C(=O)NCC(C)C)cc1 +CCCCN(CC)C(=O)CSc1nc(N)cc(N)n1 +O=C(Nc1ccc(C(=O)N2CCCC(O)C2)cc1)c1ccco1 +NC(=O)c1ccccc1NC(=O)CCC1CCCC1 +CCCC(=O)NCC(O)c1ccc(OC)c(C(C)(C)C)c1 +Cc1ncccc1C1NCCc2cc(Cl)cc(F)c21 +O=C1CCC2(CC1)CCN(C(=O)OCc1ccccc1)CC2 +O=C(COCCc1cccs1)c1cccs1 +Cc1ccccc1OCC(=O)NCc1ccccc1 +Cn1cc(CCC(=O)N2CCCCC2c2nccs2)cn1 +COc1cc(OC)cc(C(=O)c2cc(N)ccc2OC(F)F)c1 +O=c1cc(-c2cccs2)[nH]c2c(C3CC3)cnn12 +C#CCN1CCN(CC(=O)NCCc2nc3ccccc3s2)CC1 +Cc1ccc(N(C)C(=O)Cc2ccc(-n3cnnn3)cc2)c(C)c1 +Cn1c(C(=O)NCCCO)cc2c(F)cccc21 +C=CCn1c(SC2CCCCC2=O)nnc1-c1ccco1 +CC(=O)Nc1ccc(F)c(NC(=O)CNC(=O)NCc2ccco2)c1 +CC(C)c1cc(N)cc2c(CC(=O)N3CCCC3)noc12 +CC(NC(=O)c1ccc(COc2ccccc2)cc1)c1ccncc1 +COC(=O)c1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)cc1 +CCNC(=O)NCCCOC(=O)C1CCOCC1 +CCOc1ccc(OCCc2ncc(C#N)s2)cc1 +C#CC(OC(=O)c1ccc(CNC(C)=O)cc1)C1CC1 +O=C(CCCc1nc2ccccc2c(=O)[nH]1)Nc1ccc2c(c1)CCC2 +COC(=O)N1CCCc2cc(S(N)(=O)=O)ccc21 +CC(=O)c1ccc(NC(=O)c2cc(C3CC3)nc3onc(C)c23)cc1C +CCc1ccccc1NC1Nc2cc(C)nn2S1 +COc1ccc(SC2OC(CO)C(O)C(O)C2O)cc1 +COC(C)C(=O)Nc1cnn(-c2ccccc2F)c1 +O=C(NCc1noc(-c2ccccc2)n1)c1c[nH]c2ccccc12 +COc1ccc(-c2nc(-c3ccc4nncn4c3)no2)c(C)c1 +O=C(NCC1CCCN(C(F)(F)F)C1)OCc1ccccc1 +NC(=O)c1ccncc1NC(=O)c1cc2ccccn2c1 +CC(NC(=O)CNC(N)=O)c1ccc(OCc2cccnc2)cc1 +CCCNC(=O)Nc1ccc(N(C)C(C)C)c(F)c1 +CC(C)NC(=O)N1CCN(C(=O)Nc2ccccc2)CC1 +COc1ccccc1C1CC1C(=O)NCCn1c(C)nc2ccccc21 +COc1cccc(-c2c(CO)nnn2CC(C)C)c1 +Cc1ccc2nc(CN3CCOC3=O)cc(=O)n2c1 +Cc1ccc(Nc2ncnc(Nc3cc(C)on3)c2N)cc1 +Cc1cc(CN(C)C(=O)c2cccc(NC(=O)C3CC3)c2)no1 +c1cncc(-c2cc(Nc3ccncc3)nc(-c3cccnc3)n2)c1 +Cc1cc(C)nc(N(CCO)Cc2cccnc2)n1 +Cc1cc(=O)c(C(=O)NCC(C)C)nn1-c1ccccc1F +Cc1occc1C(=O)Nc1ccccc1Br +COc1ccccc1OCC(=O)Nc1ccc(-n2cnnn2)cc1 +CCN(CC(C)(C)O)C(=O)NCc1ccnc(OC(C)(C)C)c1 +Cc1ncsc1COC(=O)C1CCN(C(=O)OC(C)(C)C)C1 +COc1ccc(OC(C)C(=O)Nc2ccon2)cc1 +CCc1nnc2n1CCN(CCCn1c(=O)oc3ccccc31)C2 +CN(Cc1ccccc1)C(=O)Nc1ccccc1CC(N)=O +Cc1ccc(CNC(=O)C2Cc3ccccc3N2)s1 +Cc1cn2c(CC(=O)Nc3ccc(C(=O)N(C)C)cc3)csc2n1 +CCc1nc(CN(C)Cc2nnc(-c3cccs3)o2)cs1 +COc1ccc(C#N)cc1OCc1ccccc1F +CCn1ncc(NC(=O)c2cn(C)nc2C)c1C(N)=O +CCOc1ccc2nc(NC(=O)c3cc(C)n(C)n3)sc2c1 +O=C(CCSc1ccccc1)N1CCNCC1 +O=C(CN1CCc2ccccc2C1)N1CCOC2CCCCC21 +CC(NC(=O)c1ccccc1Cl)C(=O)NCc1ccnn1C +COc1cc(C(=O)Nc2nn3c(C)nnc3s2)cc(OC)c1OC +CCCc1n[nH]c(SC(CC)C(=O)Nc2ccc(O)cc2)n1 +CC(C)C(C(=O)N1CCC(Nc2cccnn2)CC1)n1cncn1 +Cc1ccc2nc(CNc3ccccc3)oc(=O)c2c1 +COc1cccc(OC)c1C(=O)NC1c2ccccc2CC1O +Cc1ccc(C(CNC(=O)CCC(C)(C)C)N2CCOCC2)o1 +Cc1cccc(NS(=O)(=O)c2ccc(F)c(F)c2F)c1 +NC(=O)C1CCN(C(=O)CCOCc2ccccc2)c2ccccc21 +CC(Oc1ccc(F)cc1)C(=O)Nc1ccc(F)cc1N +Cc1ccoc1C(=O)NCC(C)c1nc(-c2ccccc2)no1 +O=C(NCCc1nncn1C1CC1)c1ccn(-c2ccccc2F)n1 +O=C(NCc1nnc2ccccn12)c1cccc(N2CCCC2=O)c1 +CN(C(=O)CN1C(=O)CNc2ccccc21)C1CCCCC1 +CCOc1ncccc1C(=O)OCC(=O)Nc1ccc(C)c(F)c1 +CCOc1ccc(C(O)CCc2nc(C)cs2)cc1 +CC(NC(=O)CCCn1c(=O)oc2ccccc21)c1ccncc1 +CC(=O)Nc1cc(S(=O)(=O)NC2CC2c2ccccc2)ccc1F +NC(=O)c1oc2ccccc2c1NC(=O)c1cnccn1 +CCn1c(C(C)C)nc2cc(NC(=O)Cc3c(C)noc3C)ccc21 +O=C(CC1CCc2ccccc21)N1CCC(C(=O)N2CCCC2)CC1 +Cc1cc(-n2cnnc2CCc2ccccc2O)n(C)n1 +CCOC(=O)Nc1nc(CC(=O)NC2CCCCC2)cs1 +Cc1nsc(N2CCN(C(=O)Nc3ccc4c(c3)COC4)CC2)n1 +Cc1nc2ccc(F)cc2n1Cc1ccccc1C#N +O=C(Cn1ccc(-c2ccccc2)n1)Nc1ccc2c(c1)OCO2 +Cc1cc(C(=O)Nc2ccc(Cl)cn2)c2cc(F)ccc2n1 +CCC(=O)Nc1cccc(NC(=O)C(C)c2cccs2)c1 +Oc1cc2c(cc1Br)CCNC2C1CC=CC1 +CCN(CC1CCCO1)C(=O)Nc1nnc(C2CC2)s1 +Cc1cccc(OCCC(=O)Nc2ccc3c(c2)OCC(=O)N3)c1C +COc1ccc(NC(=O)c2cn3c(n2)COCC3)cc1Cl +O=C(Oc1cccc(Cl)c1)c1cccc(-n2cnnn2)c1 +C=CCNC(=O)Nc1cccc(OCCOC)c1 +O=C(NCc1ccccc1)c1ccc(NC(=O)C2CCCC2)cc1 +O=C(Nc1ccccc1N1CCCC1=O)c1n[nH]c2ccccc12 +C=C(C)CN(CC)C(=O)c1nc(C)n(-c2ccc(Cl)cc2)n1 +CCN(CC(=O)NCCC#N)c1ccc(C)cc1C +CC(=O)c1cc(Br)cc(F)c1OCC(C)(C)O +COC(=O)NCC(=O)Oc1cccc(C(C)(C)C)c1 +CC1CCC(C)N(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)C1 +CC(C(=O)N1CCCC(n2cncn2)C1)c1ccsc1 +Fc1cccc(F)c1CN1CCCC(c2cnccn2)C1 +COc1ccc(OC(=O)Nc2ccccc2F)cc1 +CC(NC(=O)c1cc[nH]n1)C(=O)NCc1ccco1 +CCc1ccc(O)c(NC(=O)Cc2cccc(OCC#N)c2)c1 +O=C(CSc1n[nH]c(=O)n1C1CC1)NCc1ccc2c(c1)OCO2 +COCCNC(=O)c1cnc2c(cnn2C(C)C)c1 +Cc1ccnc(SCC(=O)NCc2ccc(F)cc2)n1 +C#CCN1CCN(C(=O)NCc2ncn(C)n2)CC1 +CN(C(=O)c1c(F)cccc1F)c1ccc(S(C)(=O)=O)cc1 +CNC(=O)CCCNC(=O)c1ccc(F)cc1F +O=C(Nc1cc(O)cc(F)c1)c1ccc(Br)cn1 +CCC(=O)c1ccc(OS(=O)(=O)c2ccc(OC)cc2)cc1 +CC(=O)c1nnn(-c2cccc3c(O)cccc23)c1C +N#Cc1ccsc1NC(=O)COc1ccc(F)cc1 +CCCCN(Cc1cc2ccccc2[nH]c1=O)C(C)=O +CCCNC(=O)CSc1nccn1-c1ccccc1C +Cn1cc(C(=O)N2CCCCC2CCN2CCOCC2)cn1 +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1cccc2ncccc12 +COC(=O)C1CCCc2c1nc(C(F)(F)F)n2C +O=C(Cn1ccc2ccccc21)Nc1ccc2c(c1)COC2 +COc1ccc(C(=O)OCC(=O)Nc2ccccc2C)c(C)c1 +CCCNS(=O)(=O)c1cc(C(=O)C2CC2)ccc1OC +O=C(Cn1ccc2ccc(Cl)cc21)Nc1cnccn1 +Cc1nc(CNC(=O)c2cc(COc3ccccc3)[nH]n2)n[nH]1 +CC(=O)c1ccc(OC(=O)Cc2ccc(C)s2)cc1 +Nc1ccccc1OCC(=O)Nc1cccc(C(F)(F)F)c1 +CC(C)(C)c1ccc(CO)c(=O)n1C1CCCCC1 +Cc1cnn(CCC(=O)N2CCCc3cc(Br)ccc32)c1 +O=C(CSc1ccncc1)NCCc1ccc(F)cc1 +CCc1cc2oc(=O)cc(CN3CCNC(=O)C3CC)c2cc1Cl +CCCc1ccc(C(=O)CCN2CCOCC2)cc1 +O=C(Nc1cccc(N2CCCCC2=O)c1)c1ccncc1 +COC(=O)c1cc(C(=O)Nc2ccc(C(C)=O)cc2)c(=O)[nH]c1C +O=C(CCNC(=O)Nc1ccccc1)NCc1nnc2ccccn12 +CC(C)CCNC(=O)Cn1cnc2c(cnn2C)c1=O +CCCCOc1ccc2c(c1)C(Cn1cnnn1)NCC2 +CC(=O)N(Cc1nc(-c2ccccc2)no1)C(C)C +CCNS(=O)(=O)c1cccc(C(=O)NC2CCCC2)c1 +CC1CN(C(=O)C2CC(=O)N(Cc3ccccc3)C2)CC(C)O1 +O=C1CN(C(=O)C2CCN(c3nc4ccccc4o3)CC2)CCN1 +O=C1CCC(C(=O)NCCCn2cccn2)CN1 +CC(=O)NC(CC(=O)Nc1nncs1)c1ccccc1 +CCCS(=O)(=O)N1CCCC1C(=O)NCCc1ncc(C)s1 +COCC(O)CN(C)C(=O)CNC(=O)c1c(F)cccc1Cl +Cc1cccc(C(=O)CCc2nc(C)c(C)s2)c1 +CC(C)(Oc1ccc(F)cc1)C(=O)NCc1nnc2n1CCCCC2 +CCOC(=O)c1sc(NC(=O)CCc2cccnc2)nc1C +CCN(Cc1cccc(Cl)c1)C(=O)c1ccccc1F +COc1ccc(Cn2nccc2NC(C)=O)c(OC)c1OC +CCc1nc(COC(=O)Cc2c[nH]c3ccccc23)cs1 +Cc1cccc(=NS(=O)(=O)c2cccc(OC(F)(F)F)c2)[nH]1 +CCCCCCNC(=O)c1cnc(-c2ccco2)nc1N +CC1CCCCC1NS(=O)(=O)c1ccc2c(c1)NC(=O)CS2 +CNC(=O)Cc1noc(-c2cc(Br)cc3ccccc23)n1 +CCOC(=O)c1ccc(NC(=O)C2CC(=O)N(C(C)(C)C)C2)cc1 +COc1ccccc1OC(=O)c1ccc(OCC(F)F)nc1 +Cc1noc(C)c1C(=O)Nc1ccc2c(c1)OCCO2 +Cc1cc(NC(=O)COCc2cc(-c3cccs3)on2)no1 +O=C(c1ccc(Br)cc1Cl)N1CCCCC1CCO +N#Cc1ccccc1NCc1ccc2c(c1)OCO2 +CCc1noc(CC)c1CNC(=O)C1CCN(S(C)(=O)=O)CC1 +O=C(CCc1ccc(-c2ccccc2)[nH]1)N1CCC2(CC1)OCCO2 +CCOc1ncnc(Nc2ccc(C(=O)OC)cc2)c1N +COc1ccc2c3c(c(=O)oc2c1)CN(C(=O)c1cccs1)CC3 +O=C(NC(c1ccccc1)c1ccc2nc[nH]c2c1)c1cccnc1 +CC(Sc1nnc(C2CC2)n1C)C(=O)NC(C)c1ccc(F)cc1 +Cc1ccc(Cl)cc1S(=O)(=O)NC(C)c1ccncc1 +CSc1nnc(C)c(=O)n1COC(=O)COc1ccc(F)cc1 +O=C(Nc1cccc(Cn2ccccc2=O)c1)NC1C=CC(CO)C1 +Cc1nc2nc(C)c3c(=O)n(C(C)(C)CO)ccc3n2n1 +CS(=O)(=O)N1CCCC1C(=O)Nc1ccc2c3c(cccc13)CC2 +O=C(C1CCN(c2nc3cccnc3s2)CC1)N1CCCC1 +CC1CCC(NC(=O)c2ccc3ccccc3n2)CC1 +Cc1oc(-c2ccco2)nc1CN(C)C(C(N)=O)c1cccc(F)c1 +CCOCCNC(=O)Nc1ccc(Oc2cccc(C#N)c2)cc1 +NC(=O)Cc1ccc(NC(=O)c2cnc(C3CCCO3)s2)cc1 +CCC(NC(=O)c1cccnc1)c1ccc(Cl)cc1 +CN(C)C(=O)CN(C)C(=O)c1cc(N)ccc1Cl +Cn1cc(C2CN(Cc3cncs3)CCO2)cn1 +COCc1ccc(CN2CCOC(c3nc(C)cs3)C2)cc1 +O=C(NCCn1cccn1)Nc1ccc(Cl)cc1 +Cc1cc(=O)n(CC(=O)Nc2ccc(Cl)cc2)cn1 +CC(C)(C)Nc1cc(F)c(Br)cc1N +O=C(NC(c1nccs1)C1CC1)c1cnc(C2CCCO2)s1 +Cc1ccc(-c2noc(COC(=O)c3ccco3)n2)cc1 +NC(=O)CSc1nc(C(F)(F)F)nc2ccccc12 +Cn1cccc1C1COCCN1C(=O)c1ccc(F)cc1 +O=C(Nc1cccc(CCc2ccncc2)c1)C1CC1 +N#Cc1ccc(OCn2nnc3ccccc3c2=O)cc1 +COCC1CCCN(C(=O)C2CC(=O)N(c3ccc(F)cc3)C2)C1 +O=C(NC1CCN(c2ncccc2Cl)CC1O)c1ccccn1 +Nc1ccc(C(=O)Nc2cc(Cl)ccc2Cl)nn1 +COc1ccc(NC(=O)CC(C#N)c2cccc(OC)c2)cc1 +Cc1cc(NC(=O)c2cccnc2)n(-c2nc3ccccc3s2)n1 +Cc1ccc2cccc(NC(=O)C34CCC(C)(C(=O)O3)C4(C)C)c2n1 +O=C(Nc1ccc(NCc2nc(-c3ccsc3)no2)cc1)C1CC1 +Cc1noc(C(C)n2nnc(-c3ccc(Cl)cc3)n2)n1 +COc1ccc(NC(=O)c2cc(F)ccc2Br)cn1 +CC(C)c1noc(CCC(=O)Nc2ccc(-n3cncn3)c(F)c2)n1 +Cc1cc(C)n(C(=O)c2c(Cl)c(C)nn2C)n1 +COc1ccc(S(=O)(=O)NCCC(O)c2ccccc2)cc1 +COc1ccc(NC(=O)CSc2nnc(-c3ccoc3C)o2)cc1 +CCOC(=O)Cn1cccc(NC(=O)N(C)Cc2cnn(C)c2)c1=O +COC(=O)c1ccc(NC(=O)Cc2cccnc2)cc1 +CN(CC(=O)NC1CC1c1ccccc1Cl)c1cnccn1 +COCCN(Cc1ccco1)C(=O)c1cccc(OC)c1O +Cc1cc(C)n(CCCNC(=O)c2ncc(F)cc2F)n1 +CCCN1C(=O)CCC2CN(C(=O)CCc3ccncc3)CCC21 +O=c1ccc2ccc(Oc3nnnn3-c3ccccc3)cc2o1 +COCCNC(=O)C1CNCc2cc(C(C)C)ccc21 +NC(=O)CC1CCN(C(=O)CCn2ccccc2=O)CC1 +COc1ccc(N2CCN(Cc3ccccc3F)CC2=O)cc1 +Cc1cc(C)cc(NC(=O)COc2cccc(C(=O)N(C)C)c2)c1 +CC(NC(=O)CSc1nnnn1C)c1cccs1 +CCOC(=O)c1noc2ncnc(N(Cc3ccccc3)C(C)C)c12 +COc1ccc(C(=O)Nc2ccc3c(c2)OCC(=O)N3)c(F)c1 +COCCN(C(C)=O)c1nc(CN(C)c2ccc(C)cc2C)cs1 +CC(C)(C#N)N(C1CC1)S(=O)(=O)c1sccc1Br +Cc1cc(S(=O)(=O)NC(C)C)cc2c1NC(=O)C2(C)C +Cc1ccc(NS(=O)(=O)c2ccc(C(=O)NC(C)CO)cc2)cc1 +CCN1C(=O)Cc2cc(NC(=O)c3cc(OC)cc(OC)c3)ccc21 +Cc1nc(CNC(=O)N(C2CC2)C(C)c2ccco2)no1 +COC(=O)C12CCC(NC(=O)OCc3ccccc3)(CC1)CC2 +COCC(=O)Nc1ccc(OC)c(OCC(F)(F)F)c1 +CC(C)N(C(=O)CCn1nc2ccccn2c1=O)C1CCC1 +CCc1cc(N2CCCC2C(N)=O)nc(-c2ccncc2)n1 +CNC(=O)Cn1nc(-c2ccc(Br)cc2Cl)nc1C +Cc1cn(C)nc1C(=O)Nc1nc(-c2ccncc2)cs1 +Cc1cccc(NS(=O)(=O)c2cccc(C#N)c2)c1 +CC(=O)c1c[nH]c(C(=O)Nc2ccnc(Sc3ccccn3)c2)c1 +CCc1ccc(NC(=O)c2cn(CC)c3nc(C)ccc3c2=O)cc1 +Cc1cc(F)cc(S(=O)(=O)N(CCO)c2ccc(F)cc2F)c1 +O=C(Cc1noc(CCC(=O)c2ccccc2)n1)NC1CCCCC1 +C=CCOCc1ncn2c1CN(Cc1ccc(F)cc1)CCC2 +CCOC(=O)C(O)(c1ccc2c(c1)CCN2C(C)=O)C(F)(F)F +CCOc1ccccc1C(=O)Nc1ccnc2ccnn12 +Cn1nc(C(=O)Nc2ccc(Cn3cncn3)cc2)ccc1=O +CCN1CC2(CCC1=O)CCN(C(=O)Nc1cccc(C)c1C)CC2 +Oc1ccc(-n2nnnc2SCCn2cccn2)cc1 +CCCNC(=O)CNC(=O)c1ccccc1C(=O)c1ccc(C)cc1 +COc1cccc(C(=O)Nc2nc(-c3ccc(C)o3)cs2)c1 +c1ccc(-n2ncc(COc3cccc(-c4nnco4)c3)n2)cc1 +O=C(CSc1cccc2ccccc12)N1CCCC1 +Cc1cc(O)n2nc(C3CCN(C(=O)CC4CCCC4)C3)cc2n1 +Nc1nncc(-c2ccccc2)c1C(=O)Nc1ccccc1F +CCOc1ccccc1C(=O)Nc1nnc(-c2sc(C)nc2C)o1 +Cc1ccc(S(=O)(=O)Nc2cc(N)ccc2F)cc1C +O=C(c1ccccc1F)N1CCN(CCOc2ccc(F)cc2)CC1 +Cc1nn2c(nnc3c(=O)n(C4CC4)cnc32)c1-c1ccc(F)cc1 +C#CCNS(=O)(=O)c1cccc(C(=O)OCc2c(C)noc2C)c1 +CCc1onc(C)c1NC(=O)c1cncc(-c2ccccc2)c1 +COc1ccc(OC)c(C(=O)NC2(c3noc(C)n3)CCCC2)c1 +O=C(Nc1ccccc1)N(CCO)Cc1cccs1 +CN(C)c1ccc(NC(=O)CCOCC(F)(F)F)cn1 +N#Cc1ccccc1OCC(=O)Nc1cnc2ccccc2c1 +OC(CNc1ccc(F)cc1)COc1ccc(F)c(F)c1 +CC(NC(=O)Nc1ccccc1)C(=O)N1CCCCC1C +CCOCc1nnc(NS(=O)(=O)c2ccc(Cl)cc2)s1 +O=C(CCc1ccc(Br)cc1)NCc1nc[nH]n1 +Cn1cccc(NC(=O)c2ccc(-n3ccnn3)cc2)c1=O +O=C1CCCCCN1CCCNS(=O)(=O)c1ccc(F)cc1 +CCn1nc(C(=O)OCC(=O)N2CCCCC2)c2ccccc2c1=O +O=C(Nc1ccc(-c2nccs2)cc1)C1CCCO1 +Cc1cccc(OCCCC(=O)N2CC(=O)Nc3ccccc32)c1 +CC(C)(C)n1nc(C(=O)N2CCCC(n3cccn3)C2)cc1C1CC1 +CCc1cc(-c2ccc(S(C)(=O)=O)cc2)nc(N2CCOCC2)n1 +COc1cccc(C(C)NC(=O)COC(=O)c2sccc2C)c1 +Cc1cccc(NC(=O)CSc2ncn[nH]2)c1C +O=C(CSc1ncc(CO)n1Cc1ccccc1)N1CCCC1 +COC(=O)CCN1CCN(c2ccccc2Cl)CC1 +CN1CCCn2c1c(Br)c1ccccc12 +N#CCC(COc1ccc2ncccc2c1)N1CCOCC1 +CC1CN(C(=O)CCCNC(=O)c2cccs2)CC(C)O1 +CCn1c(SCc2nc(C)no2)nnc1N1CCOCC1 +O=C(Cn1ccc2ccccc21)Nc1nc2c(s1)COCC2 +O=C(NCCc1cccs1)C1CCN(C(=O)c2ccccc2)CC1 +CC(C)COC(=O)C(C)NS(=O)(=O)c1cnn(C)c1 +COc1ccc(CNC(=O)c2cccc(OC(C)C)c2)cc1 +CC(=O)Nc1ccc2c(COc3cccc(C#N)c3)cc(=O)oc2c1 +CSc1nsc(SCC(=O)Nc2nnc(C)s2)n1 +Cc1cc(C)c2nc(NC(=O)c3nccnc3N)sc2c1 +CCCCCC(=O)N1CCc2ccc(S(=O)(=O)N(C)C)cc21 +O=C(Nc1c(F)cccc1F)c1ccc2ccccc2n1 +COc1ccccc1CNC(=O)c1cc(C)c(C)s1 +N#Cc1cccc(C(=O)N2CCN(c3ccc(C(N)=O)cc3)CC2)c1 +N#Cc1nn(-c2nccn2-c2ccccc2)c2c1CNCC2 +Cc1cccc(CC(=O)Nc2ccc3c(c2)CC(=O)N3C)c1 +Cc1cccc(NCc2cnn3ccccc23)c1N +O=C(NCc1ccncc1)C(O)c1ccc2c(c1)OCCO2 +CCOc1ccc(-c2c(C)sc3nc[nH]c(=O)c23)cc1 +Nc1ccc(C2=Nn3c(CCc4ccccc4)nnc3SC2)cc1 +Cc1noc(CCCC(=O)Nc2ccnn2C2CCCCC2)n1 +Cc1nnc(N2CCN(C(=O)c3ccoc3C)CC2)c(C#N)c1C +Cc1cc(Nc2cc(C)n3c(=O)n(C)nc3n2)ccc1F +Cc1nc(N(C)CCn2ccc3ccccc32)c2cccnc2n1 +O=C(CNC(=O)Nc1ccccc1)NCCc1ccccc1 +Cc1cccc(C(=O)N2CCN(Cc3cccc(Cl)c3)CC2)c1 +CCN(C(=O)NCc1ccnc(OC)c1)C(C)c1cccc(OC)c1 +O=C(NCc1ccccn1)C1CCC(=O)N1Cc1cccs1 +Nc1cccc2c(C(=O)NC3CCCC3)nccc12 +C=CCNC(=O)Nc1ccc(OCC)c(Cl)c1 +CC(C)(C)CC(=O)N1CCN(CCNC(=O)c2ccccc2F)CC1 +CNC(=O)Cc1noc(CSc2ncc(-c3ccc(F)cc3)o2)n1 +CCN(C(=O)CCN1C(=O)CCc2ccccc21)c1ccccc1 +O=C1NC2(CCCc3ccccc32)Nc2ccccc21 +COCCOc1ccccc1NC(=O)Cc1cccc(F)c1F +CCN(CC(=O)Nc1c(F)cccc1F)C(=O)c1ccc(=O)[nH]c1 +Cc1ccccc1-c1nnn(CC(=O)Nc2ccccc2F)n1 +COc1ccc(NC(=O)CNc2ccc(C)cc2C)cc1OC +CCOc1cc(C#N)ccc1OCC(=O)Nc1ccccc1CC +CC(C)OCc1cccc(NC(=O)c2ccc(C(N)=O)cc2)c1 +COc1ccc(Cl)cc1CN(C)C(=O)c1cnn(C)c1 +O=C(C1CCCO1)N1CCC2(CC(Oc3ncccn3)CO2)C1 +Cc1cc(C(=O)N2CCCC2c2ccccc2Cl)no1 +Cc1cccc(Cn2cnc(NS(=O)(=O)c3c(C)n[nH]c3C)n2)c1 +CCS(=O)(=O)N1CC(C(=O)Nc2cccnc2)Oc2ccccc21 +Cc1cc(C)c2c(c1)C(O)(CC(=O)c1ccccn1)C(=O)N2 +C#Cc1cccc(NC(=O)N(C)Cc2ccc(OC)cc2)c1 +Cc1cc(CNC(=O)c2cc(C)n(Cc3cccs3)c2C)on1 +O=C(OCC1CCCO1)C1CCOc2ccccc21 +CC(CO)(NC(=O)Nc1ccc(Cn2cccn2)cc1)C1CC1 +COc1ccc(C)cc1C(O)CNC(=O)C(C)C +COCCNC(=O)c1cn(C(C)c2cccc(F)c2)nn1 +Cc1cc(Cl)ccc1OCC(=O)Nc1ccc(O)cc1 +O=C(CN1CCN(c2ccccc2)C1=O)NCc1ccco1 +COc1ccc(S(N)(=O)=O)cc1C(=O)N1CCCCCC1 +O=C(Nc1ccccc1)c1ccccc1S(=O)(=O)N1CCCCC1 +Cc1noc(-c2cccc(NC(=O)COc3ccccc3C)c2)n1 +CCCC1CN(C(=O)Nc2ccc(C(C)(C)C)nn2)CCO1 +CC1COCC(C)N1CCn1cnc2ccccc2c1=O +CCCC(C(=O)NC1CCCC1)N1Cc2ccccc2C1=O +Cc1cc2nnc(SCC(=O)NC3CCCC3)n2c(C)n1 +CN(C1CC1)S(=O)(=O)c1ccc(NC(=O)N2CCCC2)cc1 +COc1ccc(F)c(NC(=O)Cc2csc(-c3cccnc3)n2)c1 +Cc1nn(C)c(C)c1C(=O)OCc1ccc(C#N)cc1F +COc1ccc(C(=O)CNc2ccc(F)cc2)cc1 +CCOC(=O)c1ccc(NC(=O)CN2CCOCC2C2CC2)cc1 +Nc1ccc(Cn2cc(Cl)cn2)c2ncccc12 +CCc1ccc(-c2c(N)c(C(C)=O)c(C)n2C)cc1 +CCOCC1CCCN1C(=O)c1cc(C)nc2ccc(C)cc12 +Cc1ccc(-n2nnnc2SCCn2c(C)csc2=O)c(C)c1 +CC(OC(=O)CSc1ncn[nH]1)C1CCCCC1 +CCN1C(=O)Cc2cc(NC(=O)c3snnc3C)ccc21 +CCOC(=O)c1c(C)[nH]c2ccc(Br)cc12 +CC(C)C1C(=O)NCCN1C(=O)NC1CCCCC1 +Cc1cc(OCc2noc(C3CC3)n2)cc(C)c1Cl +Cc1nn(C)cc1-c1cc(C(F)(F)F)n2nccc2n1 +COc1cc2sc(=NC(=O)c3cc(C)nn3C)n(C)c2cc1OC +Cc1nnc(COC(=O)c2cn(C)nc2C(C)(C)C)n1C +CN(Cc1ccccc1N1CCCC1)C(=O)CCn1cncn1 +CC(C)CN(C(=O)c1ccc(-n2ccnn2)cc1)C1CC1 +CCc1cnc(NC(=O)N(C)C(C)CC#N)s1 +CC(=O)c1cccc(OCC(=O)c2ccn(C)c2)c1 +CN(C)C(CNC(=O)c1n[nH]c2ccccc12)c1cccs1 +CCNC(=O)c1ccc(C)c(NS(=O)(=O)c2ccc(F)cc2)c1 +CC(C)C(=O)N1CC(S(=O)(=O)c2ccc(Cl)cc2)C1 +OC(CNCc1ccc2c(c1)OCO2)c1ccccn1 +CCN1C(=O)CN2c3ccc(Br)cc3C(C)(C)C12C +CC(=O)Oc1cccc(C2NCCc3cc(F)ccc32)c1C +O=C(Nc1cccc(Br)c1)N1CCOCC1 +O=C(c1ccc(F)cc1)N1CCC2(CCCN2c2ncccn2)CC1 +Cc1cc(NC(=O)NCc2cc(F)ccc2Br)no1 +CC(C)n1cnc2ccc(-c3noc(-c4ccccn4)n3)cc21 +CCCOc1ccccc1C(C)NC(=O)c1csc(C)n1 +O=C(CC1CCCC1)NCC#Cc1ccc(N2CCOC2=O)cc1 +COCCn1nc(C(=O)N(C)CCc2ccccn2)ccc1=O +CC(C)N(C)C(=O)c1cnc2c(c1)c(=O)n(C)c(=O)n2C +CC(C)COC1CCN(C(=O)c2cc(C(C)C)n(C(C)(C)C)n2)CC1 +CC(O)CN1CCN(C(=O)Cc2ccc(C(F)(F)F)cc2)CC1 +COc1cc(COC(=O)Cc2c(C)[nH]c3ccnn3c2=O)ccc1C +COc1ccc(C2(C(C)=O)CCCCC2)cc1Cl +COc1ccc(C(=O)OCC(=O)c2ccc(C)cc2)cc1OC +CC(C)NC(=O)CN1CCN(C(=O)NC2CCCCC2C)CC1 +Cc1ccn(C)c(=O)c1NC(=O)NCc1ccnc(OC2CCC2)c1 +Cc1nc(C)n(C2CCCN(C(=O)CCc3ccc(C#N)cc3)C2)n1 +CCc1cc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)[nH]n1 +COc1cccc(NC(=O)c2cc3c(nc4sccn43)s2)c1 +Cc1cccc(NC(=O)Nc2ccc3c(c2)CCC(=O)N3)c1 +COc1ccc(-c2ccc(C(=O)NCC(C)C)c(N)n2)cc1 +CN(CC1CC1)C(=O)c1c[nH]c(C(=O)N2CCCC2)c1 +O=C(Nc1ccccc1-c1cccs1)c1ccccn1 +CC(C)c1ccccc1NCC(=O)N1CCCC(C(N)=O)C1 +Cc1c(-c2ccccc2)nc(SCCCC#N)[nH]c1=O +O=C(OCC(=O)c1ccc[nH]1)c1cncc(Br)c1 +CCCC(C)NC(=O)C(C)N1CCN(S(N)(=O)=O)CC1 +O=C1COc2c(F)cc(NC(=O)NCCN3CCNC3=O)cc2N1 +C=C(C)CS(=O)(=O)c1ccc(C(=O)CCC)cc1 +COCCN1CCN(Cc2csc(Nc3ccccc3)n2)CC1=O +CC(=O)Nc1nc(C(=O)N2CCN(c3ccccc3)CC2)cs1 +Cc1nnc(SCC(=O)NCC(F)(F)F)n1C1CC1 +O=c1[nH]c(Cc2ccccc2)nc2sc3c(c12)CCC3 +O=C(Cc1ccccc1F)N1CCN(C(=O)Nc2ccncc2)CC1 +O=c1[nH]c(Cn2c(-c3ccccc3)noc2=O)cc2ccccc12 +CC1CC1C(=O)N1CCc2c(O)nc(-c3cnccn3)nc2C1 +CCN(CC1CCOC1)C(=O)c1nc(C)n(-c2ccccc2Cl)n1 +Cn1nc(C(=O)N2CCC(Oc3cccnn3)CC2)ccc1=O +CCn1c(C(=O)NCC(=O)N2CCCCC2)cc2sccc21 +Cc1ccc(NC(=O)NCc2ncn(C)n2)c(C)c1 +O=C(NCc1cccs1)Nc1ccnn1C1CCCCC1 +Cc1nc(SCC(=O)NCc2ccccc2)c(C#N)cc1C#N +Cc1ncsc1-c1nc(CC(=O)NCc2ccccc2)no1 +Cc1cc2cc(NC(=O)N3CCC4(CC3)CC(O)CO4)ccc2o1 +Cc1nc2ncnn2c(O)c1NC(=O)Nc1ccc(Cl)cc1 +C#CCN1CCN(C(=O)c2ccc(OC)cc2)CC1 +CS(=O)c1ccc(C(=O)Nc2cccc3c2CCCC3)cc1 +CN(CC(=O)NCCOc1ccc(Cl)cc1)S(C)(=O)=O +CC(C)(C)OC(=O)NCCCNC(=O)C1(C#N)CCCCC1 +CN1CCC(C(=O)NCc2ccnc(Oc3ccccc3)c2)CC1=O +COc1cccc(-c2noc(NCc3ccccc3OC)n2)c1 +COc1ccc(OC)c(-c2cn3c4ccc(N)cc4nc3n2C)c1 +CCN(Cc1ccc(C)o1)C(=O)c1cnc2cccc(C)n2c1=O +COc1cc(C)c(S(=O)(=O)NC(C)Cn2cncn2)cc1C +Cn1cnc2cc(C(=O)Nc3cnc4ccccc4n3)ccc21 +COC(=O)c1nccnc1S(=O)(=O)NC(C)(C)C +Nc1cccc(CCc2nnc(N3CCCC3)o2)c1 +CC(C)c1nn(C)c(N2CCOCC2)c1CN(CC(F)F)C1CC1 +CC(=O)NCCC(=O)N1CCc2cc(Br)ccc21 +Cc1nc(CNC(=O)c2csc(-c3ccsc3)n2)c(C)s1 +COc1cccnc1CC1COc2c(cccc2OC)C1 +COC(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1C +Nc1c(C(=O)NCC2CC2)nsc1C(=O)NCc1ccco1 +CCN(c1ccc(C(=O)NC2CCCC2)cc1)S(C)(=O)=O +CN(C)S(=O)(=O)NCc1ccccc1OCC(F)(F)F +OCc1c(-c2ccncc2)nc2c(Cl)cc(C(F)(F)F)cn12 +CNC(=O)CN(c1ccccc1F)S(=O)(=O)C(C)C +COc1ccc(CNC(=O)c2cnc(C)cn2)c(OC)c1 +CCCNC(=O)C(C)NC(=O)CCN1CCOC1=O +COc1ccc(-c2cc(-c3ccccc3)n3ncnc3n2)cc1 +Cc1cccc2c1C(C(=O)Nc1nccs1)CNC2 +Cn1cc(S(=O)(=O)NC2CCCC2Oc2ccccc2)cn1 +OCCCNc1c2c(nc3cc(-c4ccc(Cl)cc4)nn13)CCC2 +Cc1ccc(C(O)CNC(=O)c2ccc(F)cc2)cc1C +CC(NC(=O)N(C)Cc1ccccn1)c1cccc(OC(F)F)c1 +COc1cccc(C(=O)NCCCn2cnc3ccccc32)c1O +COc1ccc(Cl)cc1Cn1cc(Br)cn1 +CC(c1ccccn1)N(C(=O)CSc1ccc(C#N)cc1)C1CC1 +Cc1cc(CNC(=O)Nc2ccc(Br)cc2Cl)on1 +Cc1cn2c(CN3CCC(OCCC(C)C)C3)c(C)nc2s1 +Cc1nn(C)c(C)c1CC(=O)Nc1cc(Cl)ccc1C(N)=O +Cc1ccc(CC(=O)N2CCCN(Cc3nccn3C)CC2)s1 +Cc1ccc2oc(=O)c3cnn(CC(=O)Nc4cccc(C)n4)c3c2c1 +CC(=O)Nc1nc(CN2CCN(c3nc(C)cs3)CC2)cs1 +COCCN1C(=O)c2ccccc2NC1c1cccc(Cl)c1 +COC(=O)CN(C)C(=O)CNC(=O)Cc1cccc2ccccc12 +CC(=Cc1ccc(-n2cccn2)cc1)c1cnccn1 +Cc1cccc(OC(=O)c2cc(S(=O)(=O)N3CCCC3)c(C)o2)c1 +CCOc1ccc(Cc2nc(-c3ccc4nnc(C)n4c3)no2)cc1 +COCCc1noc(CN2CCOC(c3nc(C(C)C)n[nH]3)C2)n1 +Cn1ccnc1CN1CCCN(C(=O)c2ccc(C#N)cc2)CC1 +CCCCN(CCO)S(=O)(=O)c1cccc(Cl)c1C +CC(=O)NC1CCCN(C(=O)Nc2cc(-c3ccccc3)on2)C1 +CC(C)Cc1nnc(NC(=O)C2(c3cccc(F)c3)CCC2)s1 +C=CCc1cccc2cc(C(=O)NCc3ccco3)c(=O)oc12 +CCC(C)NC(=O)c1cc2cnn(C(C)CC)c2nc1N +Cn1cccc1C(O)CNS(=O)(=O)c1cccc2cccnc12 +Cc1c(-c2noc(-c3ccccc3F)n2)nnn1-c1ccccc1 +CCC=CCOC(=O)COc1ccc2c(c1)CCC(=O)N2 +Nc1ccc(SCC(=O)Nc2cc(Cl)cc(Cl)c2)cn1 +Cc1cc(N2CCCCC2Cn2cccn2)nc(N)n1 +Brc1cc(Cn2ccc(C3CC3)n2)c2ncccc2c1 +O=C(NCCn1cccn1)C1COC(=O)N1Cc1ccncc1 +CC(C)=C1C(=O)Nc2ccc(S(=O)(=O)N(C)Cc3ccco3)cc21 +CCc1ccc(C2COCCN2S(=O)(=O)N(C)C)o1 +CCn1nnnc1-c1cccc(C(=O)Nc2ccncc2)c1 +CCc1cc(NCCn2cccn2)n2nc(C)c(C)c2n1 +COc1ccc(CC(=O)Nc2ccc3occc(=O)c3c2)cc1 +Cc1ccc(C(=O)N2CCC3(C2)C(=O)Nc2ccccc23)cc1F +N#Cc1ccc(-c2noc(CCC(=O)Nc3nccs3)n2)nc1 +CCCOCc1ccccc1CNC(=O)c1cccs1 +CCn1c(SCC(C)C(C)=O)nnc1C1CC1 +CCCCNC(=O)C1CCN(S(=O)(=O)N2CCC(C)CC2)CC1 +Cc1cc(=O)[nH]c2ccc(S(=O)(=O)Cc3ccccc3)cc12 +COc1cccc(C(=O)CNC(=O)c2ccccc2Cl)c1 +NC(=O)c1cccc(NC(=O)c2cc(Cl)cc(Cl)c2)c1 +Nc1nonc1-c1nnc(Cc2c(F)cccc2F)o1 +CN(c1ccccc1C(N)=O)S(=O)(=O)c1ccc(F)cc1 +Cc1nnsc1C(=O)NC1CC(=O)N(CC2CCCCC2)C1 +CCN(C(=O)COC(=O)c1ccccc1F)c1ccccc1 +COC(=O)C1C2CCC(C2)C1NC(=O)c1cccn1C +N#CCC(NC(=O)Nc1cc(Cl)ccc1Cl)c1ccccc1 +Cc1cc(NC(=O)CN(C)C(=O)CC2C=CCC2)no1 +CNC(=O)c1ccc(NC(=O)c2cnc3ccccc3n2)cc1 +Cc1ccc(C(C)C)cc1OCC(=O)N1CCCS1(=O)=O +CCCC1CN(Cc2c(C)nc3sc(C)cn23)CCO1 +COc1cc(C)c(C=Cc2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1C +COC(=O)C(C)n1cnc2c(nnn2-c2ccc(OC)cc2)c1=O +O=C(COc1ccccc1)Nc1ccc(-n2cnnn2)cc1 +CCCCn1c(CCNC(=O)C2CC2)nc2ccccc21 +NC(=O)C1CCN(C(=O)Cc2csc(-c3ccccc3)n2)C1 +Cc1nn(C)c(C)c1OCC(=O)Nc1c(F)cc(Cl)cc1Cl +N#Cc1ccc(NCC(O)c2ccc(F)c(F)c2)cc1 +Cc1cc(C2CCCN2C(=O)NC2CCCCC2)on1 +Cc1cc(C)cc(NC(=O)c2cccc(NS(C)(=O)=O)c2)c1 +CCc1nnc2sc(COc3ccc(Cl)cc3)nn12 +COCCCCCNC(=O)c1cc(F)ccc1Br +COC(=O)Cn1c(CNC(=O)C(C)(C)C)nc2ccccc21 +COc1ccc(C(C)C)cc1C(=O)CCC(=O)NC1CC1 +O=C(c1ccc(F)c(F)c1)N1CC(c2nc(-c3cccnc3)no2)C1 +Cc1nn(C(F)F)c(C)c1CC(=O)N(C)S(=O)(=O)C(C)C +CCC1CCCCCN1C(=O)c1ccc(OCC(F)F)nc1 +CCc1noc(CC)c1CC(=O)Nc1ccccc1N(C)C +Cc1nc(NCc2ccncc2)c2ccccc2c1Br +Cc1ccc2c(c1)-c1onc(C(=O)NC(C)C)c1CO2 +CC(C)C(=O)NC1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +COc1c(F)cc(NC(=O)CSc2nncs2)cc1F +COc1ccc(-c2nn3c(-c4snnc4C)nnc3s2)cc1 +CC1CC(OC(=O)CCCn2c(=O)oc3ccccc32)C(=O)O1 +Cc1ccc2ncc(C(=O)NC(C)c3ccc(-n4ccnn4)cc3)n2c1 +CC(C)N(CC(N)=O)C(=O)c1ccccc1Cc1ccccc1 +CC(C)N(Cc1cnn(C)c1)C(=O)c1csc(-c2ccco2)n1 +O=C(NCc1nc2ccccc2[nH]1)c1nc(-c2cccs2)no1 +Cc1nnc(NC(=O)N2CCN(CC(O)c3ccccc3)CC2)s1 +O=C(NCc1nnc2n1CCC2)C1COc2ccc(Cl)cc2C1 +CS(=O)(=O)NC1CCN(C(=O)CCc2ccc(C#N)cc2)CC1 +CCN(Cc1ccccc1C)C(=O)CNS(C)(=O)=O +Cc1c(C(=O)Nc2ccc(F)cc2F)nnn1-c1ccccc1F +O=C(NCCn1ncc(-c2ccccn2)c1C1CC1)c1ccccn1 +Cc1csc(C(C#N)C(=O)COC(=O)c2ccc3c(c2)OCO3)n1 +C#CCNC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1 +O=C(NCc1ccco1)c1ccc(-c2ccc3c(c2)OCCO3)s1 +Cc1ccc(C)c(OCn2ccc(C(=O)Nc3ccn(C)n3)n2)c1 +Cc1ccc2cccc(C(=O)NCCc3cccs3)c2n1 +O=C1CCCN1CC(NCC(F)(F)F)c1ccccc1 +COc1cccc(OCC(=O)Nc2nc(C(C)=O)cs2)c1 +CCOc1ccccc1COC(=O)c1ccnc(C)n1 +CN(Cc1cccc(Cl)c1)C(=O)c1n[nH]c(=O)c2ccccc12 +Cc1ccccc1C1CC(C)N(Cc2ccon2)C1 +O=C(NCCc1ccco1)C1(n2cnnn2)CCCCC1 +N#CC(NC(=O)c1ccc2[nH]nnc2c1)C1CCCCC1 +Cc1cc(CNC(=O)CCOCc2ccccc2)c(C)o1 +C#CCOC(=O)c1ccc(-n2ncc(C(=O)OCC)c2C)cc1 +COCCN(Cc1ccc(F)cc1Cl)S(=O)(=O)N(C)C +Nc1cc2c(cc1-n1cc(Br)cn1)NC(=O)CC2 +O=C(CNc1ccccc1)Nc1ccc(C(=O)NCc2ccco2)cc1 +COc1ccc(Cc2nn3c(C(C)C)nnc3s2)c(OC)c1 +CN(C)C(=O)CN(C)C(=O)CC12CC3CC(CC(C3)C1)C2 +COc1ccc(C(=O)OCC(=O)Nc2ccc3c(c2)CCC3)c(F)c1 +Cc1cc(C)nc(SCC(=O)NC2CCCCC2)n1 +COc1cc(O)cc2c1CCNC2c1cc(F)cc(C#N)c1 +CS(=O)(=O)N(Cc1ccc(Cl)cc1)C1CC1 +CC1CC(C(N)=O)c2ccccc2N1Cc1nnnn1-c1ccccc1 +CCC(OC1CCCC1)C(=O)Nc1cc(C)nn1-c1ccncc1 +CNC(=O)NCC(=O)NCCOc1ccccc1C(F)(F)F +COCc1nnc2sc(C=Cc3ccccc3OC)nn12 +Cn1c(CCCNC(=O)c2ccccn2)nc2ccccc21 +Cc1cc(C)n(CC(=O)Nc2cccc(C(F)(F)F)n2)n1 +CCOCc1ncn2c1CN(C(=O)Cc1cccc(OC)c1)CC2 +Cc1cc(NC(=O)Cn2nnc3ccccc3c2=O)n(C(C)(C)C)n1 +COc1ccc(OC)c(CN(C(=O)c2csnc2C)C2CC2)c1 +CN(C(=O)c1cc2ccccc2nc1N1CCCC1)c1nccs1 +CC(C)CNC(=O)c1cn(C)nc1-c1cccnc1 +CC(C)(C)CN1CC(NC(=O)Cc2cn3ccsc3n2)CC1=O +N#Cc1ccccc1C(N)C(=O)NCc1ccco1 +Cc1sc2ncn3nc(-c4cc(=O)[nH]c5ccccc45)nc3c2c1C +CN1CCN(C(=O)COCC2CCCO2)c2ccc(F)cc21 +CC(C)CN1CC2(CCN(C(=O)Cn3cccnc3=O)CC2)CC1=O +O=C(CCCc1ccc(Cl)c(Cl)c1)NCCCO +Cn1nnc2cc(C(=O)Oc3cccc(-n4cccn4)c3)ccc21 +Cc1nn(C)c(C)c1-c1ccc(=O)n(Cc2ccc(F)cc2)n1 +CC(C)(C)c1ccc(O)c(C(O)c2ccncc2)c1 +Cc1onc(-c2ccncn2)c1C(=O)NCCN1CCOCC1 +COCCNC(=O)C(C)Nc1ccc(C#N)c(Cl)c1 +O=C(Nc1nc2ccccc2[nH]1)c1csc(NC2CCCC2)n1 +COCc1nnc(-n2nnc(CO)c2C(C)C)s1 +COCC(C)OC(=O)c1cc(S(C)(=O)=O)c(Cl)cc1Cl +CCn1cc(C(=O)NC2CCN(CC(F)(F)F)C2)cn1 +COc1ccc(C=C(C)CN2CCN(c3nc(C)ns3)CC2)cc1 +Fc1cnccc1CNCC1COCc2nc3ccccc3n21 +CN1CC(C(=O)Nc2ccc(SC3CCCC3)cc2)CC1=O +Cc1nc(N2CC3OCCN(Cc4ccccc4)C3C2)c2cc[nH]c2n1 +CCn1c(SCc2nc(N)nc(N)n2)nnc1-c1cccc(C)c1 +Cc1ccc(C(C)NC(=O)COc2ccccc2C#N)o1 +O=C1C2CN(c3nccs3)CC2CN1c1cccnc1 +CN(CC(N)=O)C(=O)c1cc(-c2ccccc2)no1 +CCCCOC(=O)C(C)Sc1ncnc2c1cnn2C +CCC1CCCCN1C(=O)CN(C)c1ncnc2[nH]cnc12 +Cc1cc(CNC(=O)CSc2ccncc2)ccc1F +Cn1ncc2c1ncn1nc(Cn3cc(Cl)cn3)nc21 +Cc1cc(NC(=O)c2ccc(COCC(F)(F)F)cc2)no1 +Cc1occc1COC(=O)CCc1ccsc1 +Cc1ccc(C)c(S(=O)(=O)N(CCC#N)Cc2ccccn2)c1 +CS(=O)(=O)c1noc(C(=O)N2CCCCCC2)c1N +Cc1occc1C(=O)N1C2CCC1C(NC(=O)C(C)C)C2 +Cc1cnn(C2CCCC2)c1NC(=O)Cn1c(C)nc2ccccc21 +CN(Cc1nccn1C(F)F)C(=O)NCCc1ccccc1F +COc1cc2c(cc1OC)C(c1ccccc1)CC(=O)N2 +Cc1ccc(C(=O)NCC2CN3CCCCC3CO2)nc1 +CCOC(=O)CNc1ccccc1-c1nc2ccccc2[nH]c1=O +CCOCC1CCCN(C(=O)NCCC(=O)N(C)C)C1 +O=C1CC(c2cccnc2)c2ncn(-c3ccc(F)cc3)c2N1 +Cc1sc2[nH]c(=O)n(-c3ccc(F)cc3)c(=O)c2c1C +Cc1cccc(C)c1NS(=O)(=O)c1c(C)[nH]c(=O)[nH]c1=O +CCS(=O)(=O)c1ccc(N(C)Cc2ccccc2)cc1N +Cn1ccnc1SCC(=O)NCc1cccc(Cl)c1 +CCc1nn(-c2cccc(Cl)c2)c2c1CNCC2 +COCCNS(=O)(=O)c1ccc(F)c(C(F)(F)F)c1 +COCCCC1(CO)CCCN(C(=O)c2cnc(C3CC3)[nH]c2=O)C1 +CS(=O)(=O)c1ccc2c(S(C)(=O)=O)cccc2c1 +CCn1nc(C(C)C)cc1C(=O)N(C)Cc1ccsc1 +c1cc(COC2CCC3C2OCCN3CC2CCOCC2)ccn1 +Cc1nc(CC(=O)N(C)Cc2nc3ccccc3c(=O)[nH]2)cs1 +CC(=O)N1c2ccc(S(=O)(=O)Nc3ccc(C)cc3)cc2CC1C +CC(C)c1cc(C(=O)N2CCC(CCN3CCCC3=O)CC2)n(C)n1 +O=C(COc1nnc2ccccn12)Nc1ccc2c(c1)OCCCO2 +CC(=O)NCCCSc1nc2c(n1-c1ccccc1)CCCC2 +CCN(C(=O)C(C)Sc1nnc(-c2ccco2)o1)c1ccccc1 +COc1ccccc1-n1nnnc1SCC(=O)N(C(C)C)C(C)C +CCOC(=O)C1=C(Cn2cnc(C#N)n2)NC(=O)NC1 +COc1ccc(C(O)CNc2ccc(C)cc2C)cc1OC +CNS(=O)(=O)c1cc(C(=O)N2CCCCCC2)cc(C)c1C +Cc1nccn1-c1ccc(F)cc1CNC(C)c1cccc(CO)c1 +CCOC(=O)N1CCC(Nc2nc(CC)c(C)s2)CC1 +O=C1CSc2ccc(NC(=O)NC3CCCC3)cc2N1 +CCS(=O)(=O)N1CCC(C(=O)Nc2ccccc2C(C)=O)CC1 +COc1cc(NC(=O)COc2cccc3cccnc23)cc(OC)c1 +Cc1cc(C)n(CC(C)CNC(=O)c2ccccc2Cl)n1 +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)OCC1CCCCC1 +O=C(Nc1cccc(Cn2cccn2)c1)c1cn[nH]n1 +CCN(CC)C(=O)CCC(=O)N=c1[nH]c2cc(Cl)ccc2n1C +CCN(CC)C(=O)c1ccc(NC(=O)c2sc(C)cc2OC)cc1 +CCCNc1ncc(S(=O)(=O)NC(C)C(N)=O)cn1 +O=C(NC1CCC(O)CC1)N1CCCC(c2nc3ccccc3o2)C1 +Cc1nn(C)c(C)c1C(=O)N1CCN(C(=O)C2CCCO2)CC1 +CC1CN(C(=O)c2cncc(Br)c2)CC(C)O1 +COCCCNC(=O)CS(=O)(=O)c1ccc(F)cc1 +CCCNC(=O)CCCC(O)c1ccc2c(c1)OCCO2 +COc1ccc2c(c1OC)Cc1c-2nc(N)c(C#N)c1C1CCOC1 +CCCn1c(SCC=Cc2ccccc2)n[nH]c1=O +Cc1cccc(C(=O)Nc2nnc3ccccn23)c1C +Cc1nc[nH]c1-c1nccn1CCN1CCNC1=O +COc1ccc(Cn2c(=O)n(C(C)C)c(=O)c3ccccc32)cc1F +CCOCCC(=O)NCc1cc2n(n1)CCCN(C(=O)N(C)C)C2 +CCC(=O)Nc1ccc(C(=O)N2CCc3ncccc3C2)cc1 +Cc1ccoc1C(=O)NCc1nc(-c2ccccc2)n[nH]1 +CN(Cc1cc2ccccc2[nH]c1=O)S(=O)(=O)c1ccccc1 +CCC1CCCCN1C(=O)C1CN(C(=O)c2c[nH]c3ccccc23)C1 +COc1ccc(OCCN(C)C(=O)Nc2ccnn2C(C)C)cc1 +Cc1cc(NC(=O)C(C)Nc2ccn(CC(F)(F)F)n2)on1 +CC(=O)N(Cc1ccc(NC(=O)NC(C)CO)cc1)C1CC1 +CC(=O)c1ccc(S(=O)(=O)NC(C)C(=O)NC(C)C)cc1 +Cc1nn(COc2c(Cl)cccc2Cl)c(C)c1N +CCC(=O)N1CCCC1C(=O)Nc1cccc(-n2cccn2)c1 +CCOC(=O)c1cn2nc(SCC)nc2nc1C +O=C(Cn1nnc(-c2ccccc2)n1)Nc1ccc2c(c1)OCCO2 +COc1ccc(C)cc1NCCN1CCOCC1 +CN(CCC#N)C(=O)CCOCc1cccs1 +Nc1ccc(C(=O)Nc2ccccc2SC(F)F)cc1 +C=CCN(Cc1cccs1)C(=O)c1c[nH]c2c(cnn2C)c1=O +CC(C)N1CC(C(=O)N(C)c2ccc(F)cc2)CC1=O +CCc1c(C(=O)N2CCCCC2C)cnn1Cc1ccccc1 +CCC(C#N)NC(=O)c1ccc(OC)c(OC(F)F)c1 +CC(CN1CCCC1=O)NC(=O)Nc1cccc(-c2nnco2)c1 +CCOc1ccnc(N2CCN(C(=O)c3cc(Cl)c[nH]3)CC2)n1 +CCOCCC(=O)N1CCCC2(CCC(=O)N(CCC(C)C)C2)C1 +CC(=Cc1coc(-c2ccccc2)n1)c1cnccn1 +CC(NC(=O)NCc1ccccc1)c1ccc2c(c1)NC(=O)CO2 +O=C(c1ccccc1O)N1CCc2ccccc2C1 +COCCC1COC2(CCCN(C(=O)c3ccc(O)cc3)C2)C1 +CCCC(C)C(=O)NCCOc1cccc(N)c1 +CCc1nn(C)c(NC(=O)NCCc2nnc(C)s2)c1CC +COc1ccccc1CNC(=O)CSc1ncnc2nc[nH]c12 +O=C(CCN1CCOCC1)c1ccc(Br)cc1 +Cn1cc(C(=O)NCc2ccncc2)c(=O)c2cc(F)ccc21 +N#Cc1ccc(F)c(CNC(=O)NC2CCCCC2O)c1 +Cc1cccc(NC(=O)c2cnc(Cc3ccccc3)s2)n1 +Cc1cc(NC(=O)C2CCCN2C(=O)c2cccs2)no1 +O=C(Cc1cccc(O)c1)N1CCOC(c2ccc(Cl)cc2)C1 +CC(Oc1cccc(Cl)c1)C(=O)NC(C(N)=O)c1ccccc1 +O=C(c1ccc2cccnc2c1O)N1CCCC(O)(CO)CC1 +Cc1ccc(-c2ncncc2Br)cc1C +CCc1n[nH]c(SCC(=O)N2CCC(C)(O)C(O)C2)n1 +COc1ccc(NC(=O)CNc2ccc(N(C)C(C)=O)cc2)cc1 +COC(=O)c1c(C)cc(C(F)(F)F)nc1SCC#N +CCc1nc(CC(=O)OCc2ccoc2C)cs1 +N#Cc1cc(F)ccc1NCC1(CCO)CCOCC1 +CCCc1noc(CCCC(=O)N2CCOCC2C2CC2)n1 +Cc1nc(CNc2ccccc2Br)oc1C +CCOCC(=O)Nc1cc(-c2ccccc2)nn1C(C)C +COC(=O)N(C)c1ccc(NC(C)C(=O)NCc2ccccc2)cc1 +CCCc1ncc(C(=O)N2CCC(C(=O)OC)c3ccccc32)s1 +Cc1ccn2cc(C(=O)N=c3sccn3C)nc2c1 +CC(C)c1nc(CS(=O)(=O)c2nccn2C)cs1 +COc1cc(C)c(C)cc1C(=O)CNC(=O)c1cccnc1 +COCCN(Cc1cccnc1)c1ccc(Cl)c(C#N)n1 +Cc1cc(NC(=O)c2ccc(NC(=O)c3cccs3)cc2)no1 +CC(=O)NC(CC(=O)NC1CCc2c(O)cccc21)c1ccccc1 +CN(C)S(=O)(=O)c1c(O)cc(Cl)cc1Cl +CC(OC1CCN(C(=O)OC(C)(C)C)CC1)c1cccs1 +Cn1ccc(NC(=O)NC2(c3cccc(Br)c3)CC2)n1 +O=S(=O)(NCC1CCCO1)c1ccccc1C(F)(F)F +CCS(=O)(=O)NCC(=O)c1ccc2c(c1)OCO2 +CCc1ccccc1OCC(=O)NCc1cn(-c2ccccc2)nn1 +COC(=O)c1cc(NC(=O)c2occc2C)cc(C(=O)OC)c1 +COc1cccc(CN(C)C(=O)CNc2cc(C)cc(C)c2)c1OC +COc1ccccc1NC(=O)CNC(=O)c1ccc2[nH]ccc2n1 +CCCn1ncc(N2CCC(C(=O)N(C)C)CC2)cc1=O +COc1cc(CNC(=O)c2ccc(-n3ccnc3)cc2)ccn1 +COc1ccc(OC)c(C(=O)Nc2ccc(N3CCCC3)nc2)c1 +CC(C(=O)NCC(F)(F)F)N1CCN(C(=O)c2ccccc2)CC1 +Cc1cc(C)c(NC(=O)CCc2c(C)nn(CCC#N)c2C)c(C)c1 +CN(C(=O)c1ccncc1)C1CCN(c2ncnc3ccccc23)CC1 +CC(=O)Nc1ccccc1OCc1cn2ccccc2c1C#N +CCC(CO)Nc1nc(C(F)(F)F)ccc1C#N +O=C(Cn1cnc(C2CCC2)cc1=O)NCc1ccc(Cl)cc1 +COc1cn(-c2ccccc2)nc1C(=O)N(CCC#N)C(C)C +CC(NC(=O)Cn1nnn(-c2cccs2)c1=O)c1ccccc1F +CC(C)CCSc1nnc(-c2ccccc2)c(=O)n1N +CCCNC(=O)c1cn(C(C)CC)c2cccc(N)c2c1=O +O=C(C1CN(c2ncnc3[nH]ccc23)CCN1)N1CCCC1 +COc1ccc(OCC(=O)Nc2cccn3ncnc23)cc1 +N#Cc1cccc(C(=O)c2ccc3c(c2)OCCO3)c1 +COC(=O)CNC(=O)C1CCN(C(=O)c2ccc(F)cc2F)CC1 +COc1ccc(-c2nc(-c3cccc(C(=O)N4CCCC4)c3)no2)cc1 +COC(C)c1nc(CN(C)C(=O)N2C(C)CCCC2C)cs1 +Cc1ccc(CNC(=O)c2ccccc2)c(OCC2CCOC2)c1 +Cc1nn(CC(=O)OCCN2CCCC2=O)c(C)c1Cl +CN(C(=O)COc1ccccc1-c1ccccc1)C1CC1 +COc1ccc(COc2cc(N)ccc2OC)cc1OC +CCNC(=O)c1cc(S(=O)(=O)NC2CC2)ccc1C +Cc1nc2ccc(NC(=O)c3ccc4c(c3)OCO4)cc2[nH]1 +CCCc1c(C(=O)OC(C)c2ccccn2)[nH]c(C)c1C(C)=O +CCCN(C1CC1)S(=O)(=O)c1cc(N)cc(C)c1C +CCOc1cc(C)ccc1NC(=O)c1sc(C)nc1C +CCOC(=O)CNC(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1c(N)cccc1NC(=O)c1ccc(C#N)cc1 +CCOc1ccc(S(=O)(=O)N(Cc2ccccn2)C2CC2)cc1C +O=C(NCCCOC1CCCCC1)c1cncc(Br)c1 +O=C(Cc1nc2ccccc2s1)c1cccs1 +Cc1noc(CC2COC3CN(S(C)(=O)=O)CC23)n1 +Cc1ccc(CNC(=O)NCc2ccc3c(c2)OCO3)c(C)c1 +COc1ccc(N)cc1CNC(=O)CCC1CCCC1 +NS(=O)(=O)c1ccc(N2CCN(C(=O)c3ccco3)CC2)nc1 +COc1cccc(NC(=O)CSc2nnc(N(C)C)n2C(C)C)c1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)OC(C)C(N)=O +Cc1cc2nc(NCC(=O)NCc3ccccc3)c3ccccc3n2n1 +CCOc1ccccc1NC(=O)CNS(=O)(=O)c1cccs1 +CCOC(=O)c1cc(-c2ccc(O)c(OC)c2)no1 +CS(=O)(=O)c1ccc(OCCCN2CCc3ccccc32)cc1 +COCCN1C(=O)C2CCC1CN(S(=O)(=O)c1cnoc1C)C2 +N#CCn1c(CN2CCCC2Cn2cccn2)nc2ccccc2c1=O +CS(=O)(=O)NCCCNC(=O)c1cc(-c2ccccc2)on1 +Cc1ccc(C(C)n2cc(C(=O)NCC3CCCO3)nn2)cc1 +CC(=O)c1ccc2c(c1)N(CC(C)C)C(=O)C(C)N2C +COc1ccc(OC)c(C(C#N)Cc2ccc3c(c2)OCCO3)c1 +Cc1c(C(=O)NCCc2cccs2)nnn1-c1ccc(Cl)cc1 +CNc1cc(C2CCCN(C(=O)COC)C2)nc(-c2cccnc2)n1 +CCOC1COC2(CCN(S(=O)(=O)CC)CC2)C1 +O=C(NCc1ncc[nH]1)Nc1cccc(Cl)c1Cl +COc1ccc2c(c1)CCCC2(C#N)NCC(F)(F)F +CCC(C)(C)NC(=O)c1ccc2c(c1)N(C(=O)NC)CC2 +CCCC(=O)Nc1ccc(C(=O)n2nnc3ccccc32)cc1 +CC=CC=CC1NCCc2ccc(OCC)c(OC)c21 +CC(=O)c1cccc(NC(=O)Cn2cc(C)cn2)c1 +CCCC(C)CC(=O)N(C)Cc1c(C)nc2sc(C)cn12 +c1ccc(-c2cc(CNCCc3cnccn3)c3nnnn3c2)cc1 +O=C(NC1CCN(c2cccs2)CC1)N1CCOCC1C1CC1 +CC(C)CCN1CC(C(=O)N2CCN(C)CC2)CC1=O +CC(=O)c1csc(CCOc2cc(C)cc(C)c2)n1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)Cc1ccccc1F +COCC(=O)Nc1ccc(Nc2ccc3nnnn3n2)cc1 +NC(=O)Nc1cccc(CNS(=O)(=O)c2cccs2)c1 +Cn1c(C2CC2)nc2cc(NC(=O)Cc3ccccc3O)ccc21 +C#CCCN1CCN(C(=O)c2cnn(C(C)CC)c2C2CC2)CC1 +CCc1cc2c(=O)n(CC(=O)N(C)CC(F)(F)F)cnc2s1 +COc1cc(CNC(=O)Nc2cc(C)cc3cccnc23)ccn1 +Cc1ccc(Cl)cc1NCC(=O)Nc1cccc(C(N)=O)c1 +CCOC(=O)c1ccc(NC(=O)NCc2nnc3n2CCC3)cc1 +Cc1noc(C)c1CCNC(=O)c1ccc(=O)n(CC(=O)N(C)C)c1 +N#CCOc1cccc(CC(=O)NCc2ccn(C3CCCC3)n2)c1 +O=C(c1ccc(-n2cncn2)cc1)N(C1CCCCC1)C1CC1 +CN(c1ccccc1)S(=O)(=O)c1ccc(CO)cc1 +FC(F)(F)c1c[nH]c(C2CCN(c3ncnc4[nH]cnc34)CC2)n1 +CCc1noc(Cn2nnc(-c3ccccc3C)n2)n1 +CC(Nc1nccc(C(F)(F)F)n1)C(=O)NCc1ccccc1 +CCS(=O)(=O)c1ccc(NC(=O)COc2ccccc2)cc1 +CC(C(=O)Nc1ccc(NC(=O)c2ccco2)cc1)n1cncn1 +CC(C)c1ocnc1C(=O)NCC1CCCC1NS(C)(=O)=O +CCc1ccc2nc(CC3CCCCO3)[nH]c(=O)c2c1 +CN(Cc1ccccc1)C(=O)c1nc(-c2cccs2)no1 +CCN(C)c1ccccc1NC(=O)N(C)CCC(C)O +O=C(CCCOc1ccc(F)cc1)N1CCN(CCO)CC1 +COCCNS(=O)(=O)c1ccccc1OC(F)(F)F +CCOc1ccc2cc(C(=O)N3CCCC3)[nH]c2c1 +NC(=O)c1ccc(NC(=O)Nc2ccccc2Cl)cc1 +Cn1nc(C(=O)Nc2cc(Cl)c(Cl)cc2Cl)ccc1=O +Cn1cc(-c2noc(C3(c4cccc(F)c4)CCC3)n2)cn1 +O=C(Cc1cccs1)c1cnc2ccccc2c1 +CS(=O)c1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +CCC1C(=O)Nc2c(F)cc(C(O)c3cccc(C)c3)cc21 +CCOC(=O)c1cccc(S(=O)(=O)Nc2cnn(CC)c2)c1 +CNc1ccc(C(=O)N2CCN(CCO)CC2)nn1 +Cc1ccc(C(=O)Nc2ccc(C)c3ncccc23)cn1 +CCC(OC(=O)c1cn(C)nc1C)c1ccc(C)cc1 +CCC1CCc2c(sc(NC(=O)OC)c2C(N)=O)C1 +COc1ccc(CCC(=O)Nc2cccc(O)c2)cc1 +Cc1ccc(CN2C(=O)CCC2C(=O)Nc2ccc(Cl)cn2)cc1 +CCn1nc(C)c(CN(CCOC)C(=O)c2cc(C)nn2C)c1C +CNC(=O)NCC(=O)NCC(C)(C)c1cccc(Cl)c1 +CC(Oc1ccccc1)C(=O)N1CCN(c2ccccc2O)CC1 +COc1ccccc1NC(=O)c1ccc(F)cc1-n1cnnn1 +COc1cc(SC)ccc1C(=O)NCc1ccccn1 +CCOc1ncnc2c1CCN(C(=O)C1CCOCC1)CC2 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+Cc1ncc(C(=O)OCCCOC2CCCC2)s1 +Cc1ccc(C(F)(F)F)cc1NC(=O)NCc1nncn1C1CC1 +c1ccc(C2OCCC2NCc2ccccn2)cc1 +COc1ccc2c(CC(=O)Oc3ccccc3)coc2c1 +Cc1nsc(NC(=O)N2CCCC(c3ccccc3)CC2)n1 +COc1ccc(S(=O)(=O)N(C)CC(=O)Oc2ccccc2)cc1 +CCC(C(=O)NC1CCCCC1)N(c1ccccc1)S(C)(=O)=O +Cc1cc(F)ccc1CCNC(=O)c1[nH]ncc1Br +CCC(NC(=O)c1ccc(OC)nn1)c1nc(C(F)(F)F)cs1 +O=C(NCCNC(=O)N1CCCC1C1CCC1)c1ccccc1Cl +CCOC(=O)C1CCCc2c1[nH]c1c(C(N)=O)cccc21 +CC1(C)CN(C(=O)CCOCC(F)(F)F)c2ccccc2S1 +N#Cc1ccc(NC(=O)N2CCN(c3ccc(O)cc3)CC2)cc1 +O=C1Nc2ccccc2OC1C(=O)N1CCN(c2ncccn2)CC1 +N#Cc1ccc(OCc2nc(-c3ccsc3)no2)cc1 +CCOC(=O)CN(C)C(=O)c1cn(C)nc1C(C)(C)C +CCCS(=O)(=O)NCC(O)c1cc(C(C)(C)C)ccc1C +CCC(NC(=O)Nc1ccc(CC(=O)NC)cc1)c1ccc(C)cn1 +COC(=O)CCNC(=O)c1ccc(C(F)(F)F)cc1 +COc1ccccc1CNS(=O)(=O)N1CCCCCC1 +CCOC(=O)c1cc(-c2ccc(O)cc2O)nn1Cc1ccccc1 +CN(CC(=O)NCc1ccco1)c1nnc(N2CCCC2=O)s1 +CC(NC(=O)C1CCN(c2cc(Cl)ccc2Cl)C1=O)C(N)=O +O=C1OC(c2ccc(O)cc2)Cc2cc(O)cc(O)c21 +Cc1[nH]nc(C(=O)N(C)Cc2cccs2)c1N +CC(C)(C)NC(=O)CNc1cccc(C(=O)N2CCCCC2)c1 +CCCN(CCc1ccccn1)C(=O)c1nccnc1N +Cc1nn(C)c(C)c1S(=O)(=O)N1CC2CCC1C2 +CCOCCSc1nc2ccccc2c(=O)n1C +CC(Nc1ncc(Cl)cn1)c1nnc2n1CCC2 +Cc1nsc(C)c1NC(=O)CNC(=O)c1cc2sccc2n1C +CCOCCC(=O)Nc1ccc(Oc2cccnc2)nc1 +CCn1nc(C(=O)Nc2ccccc2-c2ccccc2)ccc1=O +Cc1ccccc1C(=O)NCCNc1nc2c(C)cccc2cc1C#N +CN(Cc1ccccc1)c1cnn(Cc2ccccc2F)c(=O)c1 +COC(=O)C(NS(=O)(=O)c1ccc2ccccc2c1)C(C)C +CC(NC(=O)N(C)CCc1ccc(F)cc1)C1CCCO1 +COc1ccc(NC(=O)C2CCC2)cc1NC(=O)c1ccccc1 +CNC(=O)c1cc(Cl)c(OCC(C)C)c(OC)c1 +Cc1nc(Cc2noc(C3(Cc4ccccc4)CCC3)n2)no1 +CCOc1ccc(S(=O)(=O)Nc2ccc(C#N)cc2)cc1OCC +Cc1ccsc1CN(C)C(=O)Nc1nc(C)n(C(C)C)n1 +COc1ccc(S(=O)(=O)Nc2cnccc2C)cc1 +CCC1CCCCN1C(=O)c1n[nH]c(=O)c2ccccc12 +Cc1nn(C)c2nc(N3CCCC4(CC3)CN(C)C(=O)O4)sc12 +CCCc1cc(C(=O)N2CCCC(NS(C)(=O)=O)C2)sc1C +CC1CCCC(NC(=O)Nc2cccc(C(=O)N3CCOCC3)c2)C1 +O=C(Cn1ccccc1=O)NCc1ccc2c(c1)OCCO2 +CCC(c1ncnn1Cc1cccc(C)c1)N1Cc2ccccc2C1=O +Cn1ccc2c(C(=O)NCCCc3nnc4ccccn34)cccc21 +Cc1nn(C)cc1S(=O)(=O)N(C)Cc1cnn(C)c1C +COC(=O)C1CCCC1NC(=O)c1cccc(OCC(F)F)n1 +COc1ccc2c(c1)CC(C(=O)NCc1c[nH]nc1C)CO2 +C=CCNC(=O)N1CCC(c2c[nH]c3ccc(OC)cc23)CC1 +C#CCN(C)Cc1ccc2c(c1Br)OCO2 +Cc1[nH]nc(O)c1C1(C(C#N)C#N)C2CC3CC(C2)CC1C3 +Nc1nc(-c2cccc(Cl)c2)ncc1C(=O)NC1CC1 +N#Cc1cccc(NC(=O)c2cc(Cl)c3c(c2)OCCCO3)c1 +CNC(=O)c1ccc(N2CCc3cc(Cl)cc(Cl)c3C2)nn1 +CN(Cc1cc(Br)cs1)C(=O)CN1CCOCC1 +Cc1cc(NC(=O)C(C)n2nc(-n3nc(C)cc3C)ccc2=O)on1 +Cc1cccc(-c2nnc(SCC(=O)NCC(F)(F)F)n2C)c1 +O=C(Nc1cc(C(F)(F)F)ccc1-n1ccnc1)c1ccc(F)cc1 +CC(C)NC(=O)c1cc2n(n1)CCN(Cc1ccc(F)cc1)C2=O +Cc1ccc(N2CC(OCC(=O)N(C)C)C3OCCCC32)nn1 +Cc1cc(CNc2nnc(C3COc4ccccc4O3)o2)c(C)o1 +CNC(C(=O)OC)c1cc(Cl)c2c(c1)OCCO2 +O=C(COC(=O)c1ccco1)NCc1ccc(Cl)cc1Cl +Cc1ccc(OCC(=O)Nc2cc(-n3cnnn3)ccc2Cl)cc1 +Cc1cnn(-c2ccc(C(C)NC(=O)c3cc(C)no3)cc2F)c1 +CCN(C(=O)c1cc(C(C)C)n(C)n1)C(C)COC +CC(CNC(=O)CNc1ccc(C#N)cc1)Oc1ccccc1 +CC(C)COc1cccc(C(=O)N2CCCC(C)C2)c1 +COc1ccc(Nc2ncc3c(n2)CCCC3=O)cc1 +CCC(NC(=O)NCc1cnn(C)c1)c1cccs1 +CN(C(=O)c1nnn(-c2cccc(Cl)c2)c1N)c1ccccc1 +COc1ccccc1N1CC(C(=O)NC(C)CO)CC1=O +COCCN1CCN(c2nc(C3CCCC3)nc3c2cnn3C)CC1 +COc1cccc(NC(=O)CCCc2nc3ccccc3c(=O)[nH]2)c1 +COc1ccc(CSc2cnccc2C#N)cc1 +Cn1cc(C(=O)NCc2nc3ccccc3n2C)c2ccccc2c1=O +CS(=O)(=O)c1ccc(OCCCC(=O)NC2CC2)cc1 +CC(C)c1noc(CCC(=O)N(C)CC2COc3ccccc3O2)n1 +COCc1cc(=O)[nH]c(-c2ccc(OC)c(C)c2)n1 +Cc1cnc(CCNC(=O)CCn2cnc3ccccc3c2=O)s1 +COc1cccc2c1OCC(CNC(=O)Cc1cnccn1)C2 +N#CCCNS(=O)(=O)c1cccc(C(=O)NCc2ccccc2)c1 +Cc1csc(N(C)C(=O)c2ccnc(OC3CCC3)c2)n1 +CCn1c(SCC(=O)N(C(C)C)C2CCC2)nnc1-c1ccco1 +COc1cc(C)ccc1OCC(=O)Nc1ccc(OC(F)F)cc1 +C=CCN(C(=O)c1cc(OC)c(OC)c(OC)c1)C1CCCCC1 +CCc1cc(-c2nccn2Cc2c(C)cc(C)nc2OC)on1 +COCCN(CC(=O)N(C)C)C(=O)c1ccccc1Cl +Cc1cnn(CC2CCN(c3nc(C)nc4ccsc34)CC2)c1 +COCCCN(C)C(=O)c1cc(Br)cnc1N +COc1cccc(CNC(=O)Nc2ccn(C)n2)c1 +CCOC(=O)c1cn(-c2ccc(OC)cc2)nc1N +CC(C)c1cc(C2CCCN2S(=O)(=O)Cc2ccccc2)no1 +Cc1ccc(-c2nnc(NC(=O)c3cnccn3)s2)c(C)c1 +CCCCOc1ccc(-c2[nH]ncc2C(=O)NC(C)C)cc1 +CN(CCCNC(=O)N1CCCC1c1ccncc1)S(C)(=O)=O +O=C(NCCc1ccccn1)C1CC(=O)N(c2cc(F)cc(F)c2)C1 +Nc1ccc2nc(SCC(=O)NCc3ccco3)sc2c1 +CCNC(=O)C(C)NC(=O)c1cccc2cn[nH]c12 +Cc1ccc(C(=O)CCC(=O)Oc2cccc(C(N)=O)c2)cc1 +CCc1cc(=O)[nH]c2nnc(SCC(=O)N3CCCCCC3)n12 +Cc1nc(CNC(=O)c2ccc[nH]c2=O)c(C)s1 +Cn1cnnc1CNC(=O)C1(c2cccc(F)c2)CCC1 +CCCN1C(=O)C2(OCCCCO2)c2ccccc21 +COc1ccc(F)cc1Cn1nnc(-c2cccc(F)c2)n1 +COC(=O)Cn1nc(-c2ccc(OC)c(OC)c2)ccc1=O +CCCCNC(=O)NC1CCN(c2c(F)cccc2F)C1 +Cc1cccnc1NC(=O)c1ccc(-n2ccnn2)cc1 +Cc1ccc2c(c1)SCC(=O)N2Cc1noc(C2CC2)n1 +CCn1cc(C(=O)Nc2ccc(Cl)cc2C(=O)OC)cn1 +O=C(CO)N1CCN(Cc2coc(-c3ccccc3)n2)CC1 +CCc1cc(N2CC3CCC(C2)N(CC2CC2)C3=O)nc(N(C)C)n1 +CC(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)Nc1ccccc1C#N +C=CCNC(=O)C(C#N)c1nc2ccccc2nc1N1CCOCC1 +C(=Cc1nc2sc3c(n2n1)CCNC3)c1ccccc1 +CC(C)(C)CC(=O)Nc1cccc(NS(N)(=O)=O)c1 +CCn1cnnc1CNS(=O)(=O)c1cc(F)cc(F)c1 +Cc1noc(C)c1Cc1ccc(C(=O)Nc2ccccn2)o1 +Cc1c(NC(=O)NC2CCCC(C)C2)c(=O)n(-c2ccccc2)n1C +CCOC(=O)c1cccc(NS(=O)(=O)c2ccccc2F)c1 +CC(Sc1nnc(C(F)(F)F)n1N)c1ccccc1 +Cc1cnc(N2CCC3OC(COCC4CCOCC4)CCC32)nc1 +Cc1ccc(C(=O)N2CCN(C)c3ccc(F)cc32)c(C)n1 +CC(NC(=O)c1ccccc1)C(=O)NCc1cccs1 +CCOC(=O)C(NC)c1cc(C)c(Cl)cc1OC +CCS(=O)(=O)N1CCC(C(=O)Nc2cccc(C)c2C)CC1 +Cc1cccc(C)c1OC1CCN(C(=O)NCc2cnn(C)c2)CC1 +Cc1cc(F)c(S(=O)(=O)NC(CO)C(C)C)cc1F +O=S(=O)(NCc1cn[nH]c1)c1ccccc1C(F)(F)F +CC(C)c1cc(CNC(=O)c2cnc(C3CCCO3)s2)on1 +O=C(CSc1ncnc2nc[nH]c12)c1ccc2ccccc2c1 +O=C(Cn1ccc(=O)c2ccccc21)Nc1nc2c(s1)CCC2 +Cc1nn(C)c(C)c1C(C)NC(=O)Nc1cccc(C(F)F)c1 +N#Cc1cc(COC(=O)CCc2nc(-c3ccccn3)no2)ccn1 +CC(c1cccc(F)c1)N1CCN(c2ncnc3c2cnn3C)CC1 +CCC(C)n1ncc(C(=O)Nc2n[nH]c(C)n2)c1C1CC1 +N#CC1CCCN1S(=O)(=O)c1ccc2c(c1)CC(=O)N2 +CCCn1c(=O)c2sccc2n2c(CCC(=O)NC)nnc12 +CCOC(=O)N1CCN(C(=O)c2cc(C)nn2CC)CC1 +O=C(CCc1nc2ccccc2c(=O)[nH]1)Nc1nc2c(s1)CCC2 +Cn1cc(C(=O)N2CCCC2c2ccc3c(c2)OCCCO3)cn1 +Cc1noc(C)c1C(=O)Nc1ccn(Cc2cccc3cccnc23)n1 +CCC(NCc1cc(C#N)ccc1F)C(=O)OC +CC(=O)Nc1nc(C(=O)OC2CCCC2)cs1 +CCOc1ccc(C)cc1S(=O)(=O)NCc1ccc(OC)cc1 +CCc1cc(N)cc(C)c1NC(=O)c1cc(OC)c(OC)c(OC)c1 +O=C(Nc1ccc(OCC2CC2)cc1)c1cc2ccncc2cn1 +O=C(NCCCN1CCCC1=O)Nc1cccc(Cl)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)CCc1c[nH]c2ccccc12 +COc1ccccc1NC(=O)NC1CCN(C(=O)OC(C)(C)C)CC1 +COc1ccc(C(=O)Nc2nnc(-c3ccnn3C)o2)cc1 +CCOC(=O)NCCC(=O)N(C)c1ccc(F)cc1 +CCCOc1ccc(-c2ncc(C(N)=O)c(N)n2)cc1 +CCOC(=O)CCNC(=O)Nc1nnc(C(C)C)s1 +COc1ccc(-c2nc(CCNC(=O)C3CCC3)n[nH]2)cc1 +COc1cccc(C(C#N)NCc2ccccc2OC)c1 +CC(Cc1cccc(Cl)c1)NS(=O)(=O)N(C)CCC#N +Cc1csc(N2CCN(CC(=O)N(C)C3CC3)CC2)n1 +O=C(NCCc1nnc2ccccn12)C1COc2ccc(F)cc2C1 +CCC1C(=O)Nc2c(C)cc(C(O)c3ccc(C)cc3)cc21 +N#CCS(=O)(=O)NC(Cc1ccccc1Cl)c1ccccc1 +CC(Sc1nc2ccccc2o1)C(=O)NCc1ccccc1F +Cc1cc2c(o1)CC(C)(C)CC2Nc1ncnc2c1cnn2CCO +NC(=O)C1CCN(C(=O)CCSc2nc3ccccc3s2)CC1 +CC1CCCN(C(=O)NC(C)C(=O)N2CCCCC2)C1 +COCc1cc(CC2(NCc3ccccc3)COC2)no1 +Cc1ccc2nc(NC(=O)Cc3c(C)[nH]c(=O)[nH]c3=O)sc2c1 +COc1ccc(C(=O)N(C)Cc2ccccc2)c(OC)c1 +COc1ccccc1CN(CCO)c1ncnc2c1CCC2 +CSc1n[nH]c2ncnc(NCCN3CCOCC3)c12 +Cc1ccc(C(=O)Nc2ccc(N(C)C)nc2)cc1NS(C)(=O)=O +CC(C#N)CN(C)C(=O)COc1ccc(C(N)=O)cc1 +Cc1cc(C(=O)Nc2nc(CN3CCOCC3)cs2)c(C)s1 +CN1CCc2nc(NC(=O)CCc3cccnc3)sc2C1 +CCOc1ccc(C(=O)N(CC)CC)c(OCC)c1 +Cc1ccc(CNC(=O)C2CCN(Cc3cnnn3C)CC2)cc1 +Cc1noc(C)c1NC(=O)C1Cc2cc(Cl)ccc2O1 +CC(C)CNC(=O)CSc1nc(C(F)(F)F)nc2ccccc12 +Cc1ccc2cccc(NC(=O)NCc3ncccc3C)c2n1 +O=C(c1ccco1)N1CCCCC1c1nncn1CC1CC1 +Cn1cc(-c2noc(C3(c4ccc(F)cc4)CC3)n2)cn1 +COc1ccc(O)c(C(=O)Nc2cc(C)ccn2)c1 +COc1cc(C)c(C(=O)Nc2cccc3ccc(C)nc23)cc1OC +CNC(=O)c1ccc(CN(C)C(=O)C2CC3C=CC2C3)cc1 +O=C(c1ccsc1)N1CCOC(Cc2ccccc2)C1 +O=C(CCSc1ncccn1)c1cccs1 +CCCNC(=O)c1nc(-c2ccc(N3CCC(C)CC3)cc2)no1 +Cc1ccc2c(C(=O)N(C)Cc3csc(C)n3)cc(C)nc2c1 +CCS(=O)(=O)NCCn1ncc2c1c(C)nn2C(C)C +Cc1cccc(N2CC(c3nc4ccccc4[nH]3)CC2=O)c1 +COc1ccc(C(=O)N2CCCCC2C)cc1OC +O=C(CCNC(=O)c1ccnc(-n2cnnc2)c1)Nc1ccccc1 +CC(C)C(NC(=O)Cc1ccccc1)C(=O)OCC#N +N#Cc1ccc(Sc2nnc(-c3cccnc3)n2C2CC2)nc1 +NC(=O)c1cccnc1N1CCC(n2cc(-c3ccccc3)nn2)CC1 +CCOC(=O)c1ccc(NC(=O)C(C)NC(=O)c2ccco2)cc1 +COC(=O)c1cc(Oc2ncccc2C(F)(F)F)ccc1N +CCOC(=O)c1c[nH]c(C(=O)OCC)c1C(C)C +CC(=O)c1ccc(S(=O)(=O)Nc2ccc(C(F)(F)F)cc2)cc1 +Cc1nc(-c2cccc(NC(=O)c3ccc(F)cc3)c2)cs1 +NC(=O)c1ccc(C(=O)Nc2ccccc2Oc2ccccc2)cc1 +CC(C)c1cc(C(=O)NCCCn2ccc3ccccc32)on1 +COc1cc(C(C#N)N2CCOCC2)cc(Cl)c1O +Cc1ccc(NC(=O)CCCCNC(N)=O)nc1 +Cc1nnn2c1COCC(CNS(=O)(=O)c1cccs1)C2 +Cc1csc(CNc2nc3cc(F)ccc3s2)n1 +Cn1ccnc1-c1nccn1CC(O)c1cccnc1 +COC(=O)CCSc1nnc(-c2ccc(C)cc2)n1C +O=c1c(=Cc2ccc(-c3ccccc3Cl)o2)sc2ncnn12 +CCOC(=O)NCCC(=O)NC1CCCCC1C +NC(=O)c1ccc(C(=O)Oc2ccc3c(c2)CCC(=O)N3)cc1 +CC(C)c1nn(C)cc1CNCCc1ccncc1 +CC1(C)COCCN1C(=O)c1cc2ccccc2c(=O)[nH]1 +O=C(C1CCCc2ccccc21)N1CCC(CO)CC1 +CN(c1ccccc1)C1CCN(S(C)(=O)=O)CC1 +CCN(Cc1cccc(C)c1)C(=O)C(C)NC(=O)c1ccoc1 +Cc1ccc(-c2nc(NC(=O)c3ccccn3)sc2C)cc1 +O=C(NCCCc1nc(-c2ccncc2)no1)C1CC1 +COC(=O)c1cc(N)ccc1Sc1cccc(Cl)c1 +Cc1noc(C)c1CCC(=O)N(Cc1ccco1)c1ccccn1 +CNC(=O)c1ccc(NC(=O)c2cccc(OC)c2F)cc1Cl +O=C(NC(CCO)C1CC1)C1(c2ccccc2)CCC1 +Cc1cc(=O)[nH]c(N2CCN(c3ccccc3F)CC2)n1 +Cn1ccc(COc2ccc(S(C)(=O)=O)cc2)cc1=O +Cc1nc2nc(S(=O)(=O)N3CCC(C)CC3)nn2c(C)c1C +CCCC1CC1NC(=O)Nc1ccc(Oc2cccnc2)nc1 +Cc1noc(C)c1C(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O +CN1CCC(NC(=O)C2(C)CC2(Cl)Cl)C1=O +CCn1cc(NC(=O)c2c[nH]nc2-c2cccc(Cl)c2)ccc1=O +O=C(NCCOc1ccccc1)NC1CCCCC1 +CCc1cc(CNc2cc(-c3ccn(CC)n3)nc(C)n2)on1 +COc1cccc(OCC(=O)N2CCN(C(=O)c3ccco3)CC2)c1 +O=C(c1ccoc1)N1CCN(c2ncnc3[nH]ccc23)CC(O)C1 +Cc1cc(C(=O)Nc2ccc(N3CCCC3=O)cc2)c(C)o1 +NC(=O)Cn1ccnc1-c1cc(Cl)cc(Cl)c1 +CCOc1ccc(S(=O)(=O)NCC(C)O)c2ccccc12 +Cn1nc(CNC(=O)c2cc(C3CC3)on2)cc1C1CC1 +COCC(O)c1ccc2c(c1)CN(C(=O)C(C)(C)C)CC2 +Cc1ccc(OCC(=O)N2CCCc3cc(N)ccc32)cc1C +CCOC(=O)c1nc(Cc2ccc(Cl)cc2)no1 +CN(Cc1ccccc1F)S(=O)(=O)Cc1ccccc1 +COc1cccc(Nc2ccccc2C(=O)NCc2ncn(C)n2)c1 +CN(C)c1ccccc1C#CCNC(=O)c1cc(C2CC2)on1 +C=CCN1C(=O)COc2ccc(NC(=O)C(CC)CC)cc21 +CCOCCCOC(=O)c1cnc2ccsc2c1 +O=C(NCC(O)c1ccc2ccccc2c1)c1ccoc1 +CC(C)c1nc(CNc2ccccc2C(F)(F)F)no1 +CC(NC(=O)c1ccccc1)C(=O)OCC1CC(=O)N(C2CC2)C1 +Cc1cc(C)cc(NC(=O)Cn2ccc(=O)c3cc(Cl)ccc32)c1 +COc1ccc(-c2cc(=O)n(CCNC(=O)CC(C)C)cn2)cc1 +O=C(NCC1(c2ccc(F)cc2)CCOCC1)C1CC=CCC1 +Cc1cc(C(=O)NCC2CCN(C(=O)NC(C)(C)C)CC2)no1 +CN(C)C1(C#N)CCCOc2cc(Cl)c(Cl)cc21 +COC(=O)CCC(=O)N1CCC(NC(=O)c2ccsc2)CC1 +COc1cc(N)c(C(=O)Nc2cccnc2)cc1OC +CCCNc1cc(C(=O)Nc2ccccn2)ccn1 +Cc1occc1COC(=O)c1cn(CC(=O)N(C)C)nn1 +CN(CC(=O)NCc1ccnn1C)C(=O)c1ccccc1 +O=C(c1ccc(OCC(F)F)nc1)N1CCCC(c2cn[nH]c2)C1 +O=C(NCc1ccc(Br)cc1)C1CC2CCC1O2 +O=C(NCCCOc1cccc2cccnc12)c1ccc2[nH]cnc2c1 +Cn1cncc1C(=O)c1cccc(Br)c1 +CCc1ccccc1NC(=O)C1CCCN1C(=O)c1ccc(F)cc1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)Cc1cnc(C2CC2)s1 +NC(=O)c1cccnc1N1CCOC(CCCc2ccccc2)C1 +Cc1cccc(C(C)CNC(=O)Cc2c(C)nn(C)c2C)c1 +Cc1ccccc1C(=O)N1CCN(c2ccc(C(F)(F)F)cn2)CC1 +Cc1cc(C)n(Cc2cccc(CNC(=O)C(C)NC(N)=O)c2)n1 +O=C(Nc1nc[nH]n1)c1cccc(OCc2ccccc2)c1 +CCc1cccc(C)c1NC(=O)OCC(F)(F)F +COc1ccccc1CCC(=O)N1CCn2cnnc2C1 +O=C(NCCN1CCNC1=O)c1cc(-c2ccccc2O)n[nH]1 +Cc1ccccc1C(=O)c1cnn(-c2ccccc2F)c1N +Cc1nnc2n1CCN(C(=O)c1ccccc1Oc1ccccc1)C2 +COc1ccnc(NC(=O)c2cccnc2OCC(F)(F)F)c1 +CCc1ccc(C(CO)NC(=O)OC(C)(C)C)cc1 +C#CCN1CCN(CC(=O)Nc2cccc3ccccc23)CC1 +O=C(c1ccc(O)c(Cl)c1)N1CCN(c2ccccc2O)CC1 +CCn1nnc2cc(C(=O)Nc3ccccc3C(=O)C(C)C)ccc21 +Cc1cccc(=O)n1CCCNS(=O)(=O)c1cccs1 +COc1ccc(C(O)(CCN2CCOCC2)c2ccc(C)cc2)cc1 +O=c1cc(N2CCN(c3ncnc4[nH]ccc34)CC(O)C2)nc[nH]1 +CS(=O)(=O)Nc1ccccc1C(=O)OCc1cccc(C#N)c1 +Cc1oc(-c2ccccc2)nc1CCNC(=O)C1CCC1 +CN(C(=O)C1CC(=O)N(Cc2ccco2)C1)C1(C#N)CCC1 +O=C(Cc1c[nH]c2ccccc12)Nc1ccn(CCc2ccccn2)n1 +Cn1nc(C(=O)N2CCCCC2)c2c1-c1ccccc1SC2 +CCOc1ccnc(NCC(O)c2cccnc2)n1 +Cc1noc(C)c1CC(=O)N1CCCC(c2nc3ccccc3o2)C1 +CC1CC(c2cccc(F)c2)N(C(=O)NC(C)c2nncn2C)C1 +Cc1nnc(-n2nnc(C#N)c2-c2ccco2)s1 +Cc1ccc(C(=O)NC2CCN(C(=O)Nc3ccccc3)CC2)s1 +CC1CCN(C(=O)CN2C(=O)COc3cc(O)ccc32)CC1 +CCOC(=O)C(C)Sc1ncnc2sc(C)c(C)c12 +Cc1ccc(CNS(=O)(=O)c2c(C)noc2C)cc1 +CCCCS(=O)(=O)NCC(=O)N1CCOCC1c1ccc(C)o1 +CC(=O)Nc1ccc(NC(=O)N(CCC#N)CC2CC2)c(Cl)c1 +Oc1ccc(-c2nc(Cc3ccccc3)n[nH]2)cc1 +Cn1ccc(NC(=O)N2CCC(Oc3cccc(Cl)c3)C2)n1 +COCCOC1CCN(c2ccc(C#N)nc2)CC1 +COCc1nc(C)cc(NC(C)C(O)c2c(F)cccc2F)n1 +COc1cc(CCC(=O)NCc2ccccc2)cc(OC)c1 +CC(C)Cn1nc(-c2ccc(OC(C)C)cc2)cc(N)c1=O +COCCCCNC(=O)N1CCCC2(CC=CCC2)C1 +NC(=O)N1CCCC(C(=O)NCCn2cccc2)C1 +CCc1ccc(C2COCCN2C(=O)Nc2ccccc2COC)o1 +CCOc1cccc(-c2nc3cc(N)ccc3[nH]2)c1 +CN(C)c1ncc(-c2cc(C(=O)NCCC#N)n(CC3CC3)c2)cn1 +CCOC(=O)C(C)NS(=O)(=O)c1cnn(C)c1 +Cc1cccnc1NC(=O)NCCNc1ccc2ccccc2n1 +CC(C)C(NC(=O)c1nccnc1N)c1nc(C2CC2)no1 +Cc1cnc(C(=O)NCCOCC(F)(F)F)cn1 +CCN(C)S(=O)(=O)NC(C)Cc1c(F)cccc1F +COC(=O)c1c(SCC(=O)Nc2ccc(C)cc2)nc(=O)[nH]c1C +CCOC(C)c1noc(CNc2ncnc3[nH]cnc23)n1 +O=C(Nc1ccn(Cc2ccncc2)n1)C1(c2ccccc2)CC1 +Cc1ccc2ncc(C(=O)Nc3ccc(-n4ccnc4C)nc3)n2c1 +CNc1snc(C)c1C(=O)NCCNC(=O)OC(C)(C)C +O=C(Nc1cccc(OCc2cscn2)c1)NC1CCC(O)CC1 +CCc1c(C(=O)Nc2cc(C)ccn2)[nH]c(C)c1C(C)=O +CNC(=O)c1cn(-c2ccccc2Br)nn1 +O=S(=O)(c1ccc(F)cc1)N1CCC2C1CCN2c1ncccn1 +CC(=O)c1noc(-c2ccccc2Br)n1 +Cc1ccc(Br)cc1NC(=O)N(C)C +COc1cccc(NC(=O)CSc2ccccn2)c1OC +CC(C)c1cncnc1-c1ccnc2c1ccn2C +CCCN(CCc1ccccn1)C(=O)c1ccccc1C +C=CCn1c(SCC(F)(F)F)nc2sccc2c1=O +Cc1ccc(C(=O)Nc2ccc(NC(=O)Cn3cncn3)cc2)o1 +Cc1occc1C(=O)Nc1ccccc1SCC(F)(F)F +CCc1csc(CNC(=O)Cc2ccc3c(c2)NC(=O)CO3)n1 +O=C(Cc1cccc(O)c1)N(Cc1ccco1)CC1CCCO1 +Cn1c(C(=O)NCc2ccc(F)cc2)cc2sccc21 +COc1ccc(C(=O)OCC(=O)Nc2ccccc2C(N)=O)cc1N +Cc1cnc(C(=O)N2CC3CCCC3(COc3ccccn3)C2)cn1 +CC1(C)C(=O)NCCN1C(=O)Cn1cnc2ccccc21 +CNC(=O)c1ccccc1CC1(O)c2ccccc2-c2ccccc21 +Nc1onc(-c2ccsc2)c1Cc1ccccc1 +O=C(c1ccc(-c2cc[nH]n2)nc1)N1CCCN(c2ncccn2)CC1 +Cn1cc(Br)cc1C(=O)Nc1ccc(F)cc1 +CN(Cc1nc2ccccc2s1)c1ncnc2sccc12 +CCn1c(SC2CCOC2=O)nc2ccccc21 +CC(=O)N1C=Cc2ccccc2C1CC(=O)NCCC1CCCO1 +O=C(c1ccnnc1)N1CC(Oc2cccnc2)C2OCCCC21 +Cc1ccc(CNC(=O)N(C)Cc2c(C)noc2C)cn1 +CNC(=O)C1CCCN1C(=O)CNC(=O)Cc1ccc(F)cc1F +COCC1=C(C(=O)OC)C(c2cccs2)n2ncnc2N1 +O=C(NCCc1ccc(Cl)cc1)c1nnn(-c2ccc(F)cc2)n1 +COC(=O)C1=C(C)C(C(=O)CSc2nc3ccccc3o2)=NC1C +COC1CCCN(c2cc(-c3ccc(F)cc3)nc3ccnn23)C1 +CCc1nc(C)c(C(=O)NC(C)(C)C(=O)OC)s1 +C#CCSc1nc(C2CCCC2)nc2c1c(=O)n(C)c(=O)n2C +O=C(NCCCn1nc2ccccn2c1=O)C1CCC1 +CCn1cnnc1CNC(=O)N1CCOC(CCc2ccccc2)C1 +CC(=O)N1CCCc2cc(NC(=O)C3CCCCC3)ccc21 +Nc1ccc(C(O)(C(F)(F)F)C(F)(F)F)cc1 +Cc1nc(N2CCOCC2)c2c(C)c(C)sc2n1 +Cc1cc(C)c2c(C(=O)N(C)C)cc(-c3cnn(C)c3)nc2c1 +COC(=O)c1sc(NC(=O)c2ccc(F)c(F)c2)nc1C +CCNC(=O)OCc1cc2cccc3c2n(c1=O)CCC3 +O=c1c2ccncc2ncn1Cc1ccc2c(c1)OCO2 +NC(=O)c1cncc(Oc2nc(C3CC3)ns2)c1 +CCCCN(C)S(=O)(=O)c1ccnc(NC)c1 +CNC(=O)NCC(=O)NC(C)Cc1ccc(Cl)cc1Cl +Cn1cc(CNc2cnn(CC(F)(F)F)c2)cn1 +CS(=O)(=O)NCCOC(=O)c1c(F)cccc1Cl +NC(=O)C1COCCN1c1nccc(Oc2ccc(F)cc2)n1 +NC(=O)c1cccc(Oc2ccc(NC(=O)Cc3ccc[nH]3)cc2)c1 +CCCC(=O)c1ccc(S(=O)(=O)C(C)C(=O)OC)cc1 +CC(C)(CNC(=O)NCC1(c2ccc(F)cc2)CC1)N1CCOCC1 +CC(=O)N1CCc2ccc(S(=O)(=O)Nc3ccsc3)cc21 +Cn1cnc(CNC(=O)NCC(=O)NCCc2ccccc2)n1 +CC(=O)c1ccc(NC(=O)c2ccc(-n3cccn3)cc2)cc1C +CNc1snc(C)c1C(=O)Nc1ccc(CC(=O)N(C)C)cc1 +Cc1nc(C)c(COC(=O)C2CCCN2C(=O)OC(C)(C)C)s1 +C#CCOCC1CCCN(C(=O)CCC2CCCC2)C1 +CCC(C)NC(=O)c1cccc(CNC(=O)C2(O)CCCCC2)c1 +Cn1c(-c2ccc(C#CCCO)cc2)nc2ccccc21 +COc1ccc(NC(=O)c2ccccc2S(C)(=O)=O)c(OC)c1 +COc1ccccc1OC(=O)C(C)Oc1ccccc1 +Cc1ccc(SC(C)C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1C +CCc1cccc(NC(=O)c2n[nH]c(CC)c2N)c1 +Cc1ccc(S(=O)(=O)N2CCN(Cc3ccccc3)CC2)cc1C +CC(NC(=O)NCc1ccncc1)C(=O)N1CCCCC1C +CC(C)NC(=O)Nc1ccc(C(=O)N2CCC2c2ccccc2)cc1 +NC(=O)c1ccc(=O)n(CC(=O)N2CCc3sccc3C2)n1 +CC(C)NC(=O)N1CCCC(C(=O)N(C)C2(C#N)CCC2)C1 +NS(=O)(=O)c1cccc(Oc2ccccc2Cl)c1 +CC(OC(=O)Cc1ccc(F)cc1)C(=O)Nc1ccc(F)cc1 +COC(=O)N1CCC(CNC(=O)c2cc(Cl)ccc2OC)CC1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)CCOC(C)C +CC(O)(CNc1nccnc1C#N)c1ccc(F)cc1F +O=C(Nc1cccc(CNS(=O)(=O)c2cccc(F)c2)c1)C1CC1 +Cc1ccccc1OCC(=O)NC(C)C(=O)N1CCOCC1 +COc1ccccc1Oc1ncnc(-c2cc(F)cc(F)c2)c1N +Cn1c(=O)c2c(nc(NCCCO)n2Cc2ccccc2)n(C)c1=O +COC(=O)c1c(NC(=O)Cc2csc(C)n2)sc(C)c1C +CCSc1nc(CC(=O)NCCc2cccs2)cs1 +COc1ccccc1CNc1nc2ccccc2n1C +O=C(NCCCO)c1cc(-c2ccccc2Cl)[nH]n1 +CCC(C)C(NC(=O)c1cc(C)sc1C)C(N)=O +CC(OC(=O)c1cnc(C2CCCO2)s1)c1ccc(F)c(F)c1 +CC(C)CCC(=O)N1CCC(OCc2ccccc2F)CC1 +CCn1cc(NC(=O)Cn2nc(C(F)F)cc2C)c(C(N)=O)n1 +CC(NC(=O)c1cc(C2CC2)nc2c1c(=O)[nH]n2C)C1CCCO1 +C=C(C)CN1C(=O)CNc2cc(Cl)c(Cl)cc21 +Cc1ccc(S(=O)(=O)NCCc2c(F)cccc2F)s1 +O=C(CCCCC(=O)Nc1ccncc1)Nc1ccncc1 +NC(=O)CCCNC(=O)Cn1cccc(C(F)(F)F)c1=O +COCCC(=O)Nc1cnc(N2CCCCCC2)nc1 +Cc1cnc(C(=O)NC(C)Cc2cccs2)cn1 +COC(=O)C1=C(N)Oc2cc(C)n(C)c(=O)c2C1c1ccc(F)cc1 +COCC(NC(=O)c1cn(CC(C)C)c2ccccc12)C(N)=O +CC(NC(=O)N(C)CCc1ccccc1)C(=O)N1CCCCC1 +CC(=O)NC1CCCN(C(=O)CSc2nnc(C)s2)C1 +Cc1cc2nc(C)c(CCC(=O)N(C)CC3CCCC3)c(C)n2n1 +COc1cc(NC(=O)c2ccc(NC3CC3)nc2)cc(OC)c1 +COc1nn(C)c2c1CCCN(C(=O)c1ccc(F)c(F)c1)C2 +Cc1ccc(CCC(=O)NCC(=O)C(C#N)c2nc(C)cs2)cc1 +Cc1cc(C)nc(NC(=O)COc2ccc(F)c(Cl)c2)n1 +CCC(CC)c1nnc(NC(=O)C(C)c2cccs2)s1 +O=C(Nc1cccc(NC(=O)C2CCCO2)n1)C1CCCO1 +Cn1c(=O)c2ccccc2n2c(CNc3ccc(F)cc3F)nnc12 +COC(=O)CC(NC(=O)c1cccc(C#N)c1)c1ccc(OC)cc1 +Cc1csc(CCCCNC(=O)Nc2cc(F)ccc2Cl)n1 +COc1cccc(C2C3(C#N)C(N)=NC(OC)(OC)C23C#N)c1OC +Cc1csc(SCC(=O)Nc2ccc(CC#N)cc2)n1 +CN(CCc1ccc(F)cc1)C(=O)c1cccnc1 +COC(=O)c1c(N)cnn1CCOCc1ccccc1 +NC(=O)NCCCCC(=O)NCc1ccc2ccccc2c1 +CC(C)NC(=O)c1ccccc1NC(=O)Cc1ccc(Cl)cc1 +N#CCn1nnc(C#N)c1-c1ccc(F)c(F)c1F +Cc1ccccc1N1CC(C(=O)NCC(C)C)CC1=O +COCCCNC(=O)Nc1ccc(Cl)cc1C(F)(F)F +COc1ccccc1Cc1nc2ccccn2c1C#N +O=C(COc1ccc(F)cc1)Oc1cccc(F)c1 +COc1ccccc1CCN1C(=O)c2ccccc2S1(=O)=O +COc1ccc(C(C)NCc2nnc(C)s2)cc1Br +O=C(c1nccc2ccccc12)N1CCC(c2n[nH]c(C3CC3)n2)CC1 +COCCCNC(=O)Nc1ccc(SC)cc1 +CCN(CC1CC1)C(=O)Nc1ccc(NC(=O)OC)cc1 +Cc1cc(C)n(CC2CCCN2C(=O)COc2cccnc2)n1 +CCCC(=O)NCC(=O)OCc1ccc(F)cc1Br +COc1cccc(C(=O)OCC2CCCCO2)c1OC +CC(C)CN(C(=O)c1cnn(C)c1N)C1CCCCC1 +COc1ccc(Cl)cc1CNC(=O)N1CCCC1 +COc1cccc(NC(=O)Cc2ccc(S(=O)(=O)C(C)C)cc2)c1 +N#Cc1cccnc1N1CCC(C(=O)NCC(F)(F)F)CC1 +CCOc1ccc(Cl)cc1S(=O)(=O)N1CCOCC1 +COC(=O)C(C)(C)NC(=O)C1CC1c1ccc(F)cc1 +CC(=O)NCc1ccc(C(=O)Nc2ccccc2OCC(C)C)cc1 +CCc1noc(C(C)Sc2nnc(COc3ccccc3)n2N)n1 +CCCNC(=O)C(Cc1c[nH]c2ccccc12)NC(N)=O +Cc1ccc(NC(=O)CNC(=O)c2ccc(N)cc2)cc1 +CCCn1c2c(cc(-c3csc(NC)n3)c1=O)CCC2 +COCC1CCCN(C(=O)c2cnn(-c3ccncc3)c2C)C1 +CC(C)(C)NC(=O)CNC(=O)NC1CCC(O)CC1 +CN(Cc1cccc(N(C)C)c1)CC(O)c1ccc(Cl)cc1 +C=CCn1c(NCC2CCCO2)nc2sc3c(c2c1=O)CCCC3 +CC1CCCCN1C(=O)CSc1n[nH]c(=O)n1CC1CCCO1 +CC(C)n1nc(C(=O)Nc2ccccn2)c2ccccc2c1=O +Nc1nc2cc(-c3cccc(C(F)(F)F)c3)ccn2n1 +CCC(C)NC(=O)C(C)NC(=O)c1ccccc1Cl +COc1cc(F)c(C(C)NC(=O)c2cc(C)ccc2F)cc1OC +COC(=O)c1cccc(C(=O)Oc2cccc(C)c2)n1 +CCCOc1cccc(-c2ccc(CO)c(=O)n2C(C)C)c1 +CN(CC1CCOCC1)C(=O)c1ccc(Br)cc1 +CCNC(=O)c1cccc(NC(=O)CS(=O)c2ccc(C)cn2)c1 +CC(NC(=O)Cn1ccnc1)c1cccc2ccccc12 +Cc1cc(OCC(=O)NC(C(N)=O)C(C)(C)C)ccc1C(C)C +COC(=O)C1Cc2ccccc2CN1C(=O)CN(C)CCC#N +COc1cccc2c1OCC(NS(=O)(=O)N(C)C(C)C)C2 +O=C(NCc1ccc(N2CCCCC2=O)cc1)NC1CCC(O)CC1 +CC(=O)c1cc(C(=O)N(C)C2CCCCC2)n(C)c1 +CCCCNC(=O)N1CCN(c2ncccn2)CC1 +CN1CC(C(=O)Nc2cc(C(F)(F)F)ccc2F)CC1=O +CC#CC(=O)N1CCC(CCC(=O)NCCOC)CC1 +Cc1ccc(-c2ccc(=O)n(CC(=O)NC3CCCC3)n2)cc1 +Cc1ccc(-c2cn(CC(=O)NCc3ccc(C)o3)c(=O)o2)cc1 +O=C(c1cc2ccccc2oc1=O)N(Cc1ccco1)Cc1ccco1 +CCC(Cc1ccccc1)NC(=O)c1c(C)c(C)nn(C)c1=O +CC(=O)c1ccccc1NC(=O)c1cc(F)c(F)c(F)c1 +Cc1ccc2c(Br)cnc(NCCO)c2c1 +Cc1ccc(NC(=O)N(C)Cc2csc(C)n2)cc1 +CCn1cc(NC(=O)NCc2cn(-c3ccc(F)cc3)nc2C)cn1 +COc1cccc(C(=O)Nc2cccc(S(N)(=O)=O)c2)c1 +CCOc1cc(C2Nc3ccc(Cl)cc3C(=O)N2C)ccc1OC +CCOC(=O)c1cccc2nc(C(C)C)n(C3CC3)c12 +CC(=O)Nc1ccc2c(c1)nc(CCN1CCOCC1)n2C +CC(OC(=O)c1c(F)cccc1F)c1nc(N)nc(N(C)C)n1 +CCSc1ccc(NC(=O)Cc2ccccc2F)cn1 +N#CCCSc1ccccc1NC(=O)C1CC=CC1 +O=C1CCCN1c1ccc(NCc2cccc3cccnc23)cc1 +CCOC(=O)c1ccc(NC(=O)C(C)(C)CC)c(O)c1 +CC(NC(=O)Cc1ccc(C(F)(F)F)cc1)c1nnc2n1CCC2 +Cc1ccc(S(=O)(=O)NCc2ccc(C(F)(F)F)cc2)s1 +CCCNc1nc(-c2csc(COC)n2)cs1 +Cc1ccc(C(C)C)c(OCC(=O)Nc2cccn(C)c2=O)c1 +Cc1cccc(C(=O)Nc2cccc(-c3ccc4nncn4n3)c2)c1 +CC(C)NC(=O)CCc1ccc(NC(=O)c2cccs2)cc1 +COS(=O)(=O)NC1CC1(c1ccccc1)c1ccccc1 +O=C(Cc1cccc(O)c1)NC1CCN(C2CC2)C1=O +CC(=O)c1ccc(Oc2ccc(C(=O)NCc3ccnn3C)cc2)cc1 +O=C(NC1CCCc2c1cnn2CCO)c1nc2ccccc2[nH]1 +O=S(=O)(c1cccs1)N(CCC(F)(F)F)C1CCC1 +CSc1ccccc1C(=O)Nc1cc(C)nn1-c1ccccc1 +CCC(C)NC(=O)NCCCc1cn(-c2ccccc2)nc1C +CNc1ncnc2c1cnn2C1CCCCCC1O +CN(C)c1nc(N)nc(Cn2c(=O)c(C#N)cn(C3CC3)c2=O)n1 +CCN1CC(C(=O)Nc2ccccc2C(N)=O)CC1=O +CC(C)C(C(=O)N1CCOCC1)n1nnc2ccccc2c1=O +Cc1cc(C)c2c(N3CCOC(CC(C)C)C3)ncnc2n1 +O=C(COc1ccccc1F)NCCCn1ccc2ccccc21 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)NC1CC=CC1 +CC(C)(C)c1nnc(Nc2cccc(N)c2)[nH]c1=O +COc1ccc2c(N3CCc4ccccc4C3)ncnc2c1 +CCn1cnnc1CNC(=O)c1cc(Cl)cc2cccnc12 +CC(C)(C)n1cc(NCc2cnc(-c3ccccn3)s2)cn1 +Cc1ccccc1C(=O)OCC(=O)NC1CCCC1 +COC(=O)CNC(=O)C12CC3(C)CC(C)(CC(C)(C3)C1)C2 +CC1(C)C2CCC1(C)C(NC(=O)Nc1cn[nH]c1)C2 +CCOC(=O)C=C(Nc1ccc(Cl)cc1N)c1ccco1 +CC(NC(=O)c1ccc2c(c1)NC(=O)CO2)c1ccccc1F +CCCC(=O)Nc1cc(N2CCOCC2)c(N)cc1Cl +COC(=O)c1ccc(F)c(CNC(=O)c2cccnc2)c1 +Cc1nc2sccc2c(=O)n1NC(=O)CCc1cc(F)ccc1F +CC(=O)c1ccc2c(c1)nc(Cc1ccccc1)n2C +C#CCCOC(=O)c1cnn(Cc2ccccc2Cl)c1 +CC(Nc1ccc(NC(=O)C2CC2)cc1)C(=O)Nc1cccc(C#N)c1 +CC(C)Cc1nnc(NC(=O)C2CC(=O)N(C(C)(C)C)C2)s1 +O=C(Nc1ccc(CNS(=O)(=O)c2cccc(F)c2)cc1)C1CC1 +O=C(CCOc1ccc2ccccc2c1)Nc1nnc(C2CC2)s1 +COC(=O)c1ccc(Cn2ccnc2-c2ccccn2)cc1 +O=C(NCc1nnc(-c2cccs2)o1)C1(c2ccc(F)cc2)CC1 +Cc1nc(CCNC(=O)C2CC(=O)OC23CCCC3)cc(=O)[nH]1 +COCc1ccccc1NC(=O)Nc1ccc(F)cc1F +CCNC(=O)Nc1ccc(OC)c(NC(=O)COC)c1 +Cc1cccc(-n2ccc3c(cnc4nc(C)nn43)c2=O)c1 +COCCCNC(=O)Nc1cc(C(N)=O)ccc1C +COC(=O)C(C)(C)NC(=O)c1cc(Br)cn1C(C)C +O=C(Cn1cncn1)c1ccc(Cl)cc1Cl +O=C(Nc1ccc2c(c1)CCC2)C1CC1(Cl)Cl +Cc1ccc(C)c(SCC(=O)N2CCN(C(=O)CO)CC2)c1 +CCNc1nc(-c2cnc(-c3cnccn3)s2)cs1 +CCOC(=O)C(NC(C)=O)(OC(C)C)C(F)(F)F +Cc1cc(C)c(NC(=O)CNc2cnc3ccccc3n2)c(C)c1 +CCOC(=O)CC(NC)C(=O)c1ccc2c(c1)OCO2 +Cc1cc(-c2nnc(NC(=O)c3ccccc3Cl)o2)nn1C +CCOC(=O)C(O)(c1cc(C(C)=O)ccc1Cl)C(F)(F)F +O=C(Nc1ccc(F)c(Cl)c1)C1COc2ccccc2O1 +CC(=O)NC(C)C(=O)Nc1ccc(F)c(Cl)c1 +CCNC(=O)CNC(=O)c1ccccc1N(C)c1ccccc1 +Cc1nn2c(-c3cccnc3)ccnc2c1-c1ccccc1 +CCn1cnnc1CCn1cc(-c2ccc(OC)nc2)nn1 +O=C(NCc1cscn1)NC(c1ccccc1)C1CCC1 +CN(CCCNC(=O)c1ccccc1Cl)S(C)(=O)=O +COCCn1cc(NC(=O)c2c(C)n[nH]c2N)cn1 +CCCNc1cccc(C(=O)Nc2nccs2)n1 +Cc1cccc(NC(=O)Cc2nc(-c3ccccn3)n[nH]2)c1 +CC(=O)c1sc(N(C)C2CCCCC2)nc1C +CCOc1ncccc1C(=O)NC(C)c1ccc(Br)cc1 +Cc1n[nH]c(-c2ccccc2NC(=O)CCn2ccc3ccccc32)n1 +Cc1cc(O)c2c(=O)c(-c3csc(C)n3)c(C(F)(F)F)oc2c1 +Cc1cc(C(=O)Cn2cnn(C)c2=O)c(C)n1Cc1ccccc1 +Cc1onc(-c2ccccc2)c1C(=O)OCC(=O)c1ccc[nH]1 +N#Cc1ccc(OCCOC(=O)C2CCOc3ccccc32)cc1 +COCCNC(=O)N1CCC(NC(=O)c2ccoc2C)CC1 +Cc1ncc(C(=O)NCc2cnn(C(C)C)c2)c(C)n1 +O=C(NCCc1nnc2n1CCCCC2)NCC1CC2CCC1C2 +O=C1NC(c2ccc(F)c(F)c2)Nc2cc(Cl)ccc21 +CCCCOC(=O)CNC(=O)c1cnc2ccc(C)cn12 +Cc1cc(C(=O)N2CC(C)OC(c3ccccc3)C2)nn1C(C)(C)C +Cc1ccc(C)n1-c1c(C(=O)NC2CC2)sc2ncccc12 +Cc1ccc(C(=O)NCCCc2c[nH]c3ccccc23)cn1 +COc1cc(Cl)ccc1C(=O)OCC1CCCO1 +C#CCN1CCN(C(=O)Nc2ccc(F)c(C(N)=O)c2)CC1 +Cc1cc(=O)n(C)cc1NC(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +Nc1nonc1-c1nc(-c2ccc(F)cc2)cs1 +COc1cccc(C(=O)Nc2nc(C)cs2)c1OC +Nc1ncccc1C(=O)N1CCN(c2ccccc2)CC1 +CCOC(=O)CCC(C)NC(=O)NC1CC=CC1 +COCCN(c1ccc(C#N)cc1F)C(C)C1CC1 +O=C(Cc1ccc(NC(=O)NC2CC2)cc1)NCc1cccs1 +Cc1ccc(C(=O)Oc2ccc(Cl)c(C)c2)c(=O)[nH]1 +O=C(c1ccc2c(c1)CCCC2)N1CCN(Cc2ccccn2)CC1 +COc1ccc(CN(C)S(=O)(=O)c2ccc(F)c(F)c2)cc1F +CSc1nccn1-c1cccc(C(=O)NCc2cnc(C)s2)c1 +Cc1cc(C)c(CNC(=O)N(C)Cc2cnc(C)s2)c(=O)[nH]1 +Cc1occc1-c1nnc2sc(-c3ccccc3F)nn12 +CCCOc1ccccc1C1NC(=O)NC(C)=C1C(=O)OCC +CCN(CCc1ccccc1)C(=O)c1cc(OC)c(C)c(OC)c1 +COCCN1CCN(C(=O)NC2CCc3ccc(F)cc32)CC1=O +CCCC(=O)N1CCC(n2nnc3cc(F)ccc3c2=O)CC1 +Cc1ccc(F)c(NC(=O)NCc2ccccc2)c1 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+CC(=O)c1cnc(NC(=O)C(CC(C)C)N2CCCCC2=O)s1 +Cc1nc(SCC(=O)Nc2ccccc2)oc1C +O=C(NCc1ccc2c(c1)OCO2)C1COC(=O)N1CC1CCOC1 +Nc1cccc(OCCCn2nnc3cc(F)c(F)cc32)c1 +CCC(C)C(NC(=O)c1cnn(-c2ccncc2)c1C)C(N)=O +CCC1CCCN(C(=O)c2cccc(F)c2F)C1 +CC(C)C(=O)N(Cc1ccccc1OS(C)(=O)=O)C1CC1 +COC(=O)CNC(=O)c1cccnc1SC(C)C +COc1cc(CO)cc2c1OCC(=O)N2Cc1ccc(C)cc1 +COc1cccc2c1NC(C)CC2N1CCOCC1 +CC(Cc1cccc(C(F)(F)F)c1)C(=O)Nc1ccnc2ccnn12 +CCc1nc(N2CCOCC2)c2c(n1)c(C)nn2CC +COc1ccc(CNC(=O)C2CCCCC2)cc1NC(C)=O +COc1cc2nc3n(N)c(=O)c(C)nn3c(=O)c2cc1OC +CC(C)(O)CN1CCN(C(=O)C2Cc3ccccc3S2)CC1 +Cc1nn(C)cc1CN(C)C(c1ccccc1)C(F)(F)F +N#Cc1ccc(N2CCN(CCO)CC2)cc1Cl +CC(=O)Nc1nc(C(=O)N2CCc3ccccc3C2)cs1 +Cc1cc(C)n2nc(Sc3ncnc4cc(F)c(F)cc34)nc2n1 +COCC(=O)N1CCCC(c2cc(C(F)(F)F)nc3nccn23)C1 +CC(CC(N)=O)C(=O)NCCc1c[nH]c2ccccc12 +CC(CO)NC(=O)CS(=O)(=O)c1ccc(Cl)cc1 +Cc1nnc(SCCCNC(=O)c2ccn3nnnc3c2)s1 +CN(C)S(=O)(=O)c1ccc(CNc2ccc(Cl)cn2)cc1 +C=CCNC(=O)c1ccccc1NC(=O)c1ccc(OC(C)C)nc1 +Cc1cc(N2CCC(=O)CC2)nc(-c2cccc(F)c2)n1 +Cn1nc(C2CC2)cc1NC(=O)N1CCC(O)(c2ccccc2)CC1 +Cc1cccc(CNC(=O)c2cc(F)ccc2F)c1 +O=S(=O)(NCCCn1ccc2cccnc21)c1cccc(F)c1 +C#CCOc1ccccc1OCC(=O)Nc1cc(C)nn1C(C)(C)C +CC(C)CCNC(=O)C(N)c1cccc2cc[nH]c12 +CC(C)(C)OC(=O)NC(c1noc(C2CCC2)n1)C1CC1 +COC(=O)N1CCC(CNC(=O)c2cc(C)on2)CC1 +COc1ccccc1OCc1ccc(C(=O)Nc2cccnc2)o1 +CCC(C)NC(=O)c1cnn(Cc2ccccc2)c1 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)N1CCCC1 +CCc1nnc(NC(=O)N(C)CCOc2ccc(OC)cc2)s1 +NC(=O)CCN(CCC(N)=O)c1nc2ccccc2s1 +COc1cccc(CNC(=O)c2cn(-c3ccc(C)cc3)nn2)c1 +CCN(Cc1cc2ccccc2[nH]c1=O)C(=O)c1ccc(Cl)cc1 +NC(=O)NCC(=O)N1CCN(c2ccccc2Cl)C(=O)C1 +COc1ccc(-c2cc(=O)n3ncc(C(C)C)c3[nH]2)cc1OC +Cc1cnn(CC2CN(CCC(=O)Nc3cc(C)on3)CCO2)c1 +COCCS(=O)(=O)NC1(c2ccc(Cl)cc2)CCOCC1 +C#CCN1CCCC1C(=O)Nn1cnc2ccccc21 +COc1cccc(C(=O)Nc2c(C)cccc2C)c1F +O=C(NCc1ccc(Cl)cc1)c1cn(-c2ccccc2)nn1 +O=C1COc2ccc(C(=O)C3COCCO3)cc2N1 +Cc1nc2cc(C(=O)OCCCc3ccncc3)cnc2[nH]1 +N#Cc1cc(F)c(C(=O)Nc2cccc(CO)c2)c(F)c1 +O=c1c2[nH]c3ccc(F)cc3c2ncn1Cc1ccco1 +CN(C(=O)Cc1cccs1)c1cccc2ncccc12 +Cc1csc(CNC(=O)c2ccc(OCc3nccn3C)cc2)n1 +CNC(=O)NCC(=O)N1CCCC1Cc1cccc(F)c1 +COC(=O)CCCN(C)C(=O)c1ccc(-n2ccnn2)cc1 +CCC(C)(C#N)NC(=O)CCc1cc(Cl)cs1 +COc1ccc(NC(=O)c2cc(S(N)(=O)=O)oc2C)cc1Cl +Cc1cnn(CCc2nnc(NCC(C)C)s2)c1 +CCN(C(=O)c1cccs1)C(C)c1ccc(C#N)cc1 +CC(C)S(=O)(=O)c1ccc(C(O)C(=O)NC2CC2)cc1 +O=C(Nc1ccc(C(F)(F)F)cc1)N(CCCO)CC(F)(F)F +COc1cc(C(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)ccc1C +Cc1nc(COc2cccc(C(=O)NCC3CCOC3)c2)cs1 +CC(Sc1ncnc2c1cnn2C)c1nc(-c2ccco2)no1 +Cc1cc(C(=O)N2CCn3c(C)nnc3C2)ccc1N1CCNC1=O +O=C(CCCC(O)c1ccc(F)cc1)N1CCCCC1 +CC1c2ccsc2CCN1c1ncnc2c1cnn2CCO +Cn1cnc(CNC(=O)NCC(C)(C)c2ccc3c(c2)OCCO3)n1 +Cc1ocnc1CNC(=O)Nc1ccc2c(c1)Cc1ccccc1-2 +COC(=O)C(C)n1ccc(=O)c2cc(Br)ccc21 +CCCS(=O)(=O)N1CCOC2C(Oc3ncccc3F)CCC21 +CC(C)=CC1C(C(=O)N2CCn3c(C)nnc3C2)C1(C)C +COCCS(=O)(=O)NCC(O)c1ccccc1Cl +CCOC(=O)CC(C)Cn1c(=O)[nH]c2ccccc2c1=O +CC(OC(=O)c1cc(=O)c2ccccc2o1)C(=O)NC1CCCC1 +COc1ccc(C(=O)N(C)C)cc1NCC1CCCC(C)C1 +NS(=O)(=O)c1cnc(NCc2ccc(-c3ccccc3)o2)s1 +CC(C)(CNC(=O)c1cccc(F)c1N)c1ccccc1 +COc1c(C)cnc(CNC(=O)NCc2cccc(C(N)=O)c2)c1C +CN(C)c1ccc(C(=O)Nc2ccc(O)cc2)cn1 +CC(=O)c1ccc(C(=O)Nc2nnc(Cc3ccccc3)o2)cc1 +Cc1nc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)cs1 +Cc1cccc(C(C)C)c1NCC(=O)Nc1ccc(CC#N)cc1 +CN(CC(=O)Nc1c(F)cccc1N1CCCC1)S(C)(=O)=O +O=C(N1CCOCC1)N1CCCC1c1nc(-c2ccccc2)no1 +CC(Cn1cccn1)NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +Cn1cc(CNC(=O)c2nc3ncccn3n2)cn1 +O=C(CC1CCCC1)NCc1noc(Cc2ccccc2)n1 +CCOc1ccc(NC(=O)c2ccc(OCC(F)F)nc2)cn1 +Cc1ccc(C(=O)OCc2cccc(C(N)=O)c2)cc1F +CCC(C)NC(=O)NCCc1ccccc1OC +CC(C)CCOC1CCCCC1NC(=O)c1n[nH]c2c1CCC2 +COc1ccc(C(=O)Nc2c(C(=O)N(C)C)nn(C)c2C)cc1 +Cc1cccc(C(=O)NCCC(=O)Nc2cccc(C#N)c2)c1 +Nc1ccc(-c2nc3cc4c(cc3n2CC(O)CO)OCCO4)cc1 +CCC(CC)C(=O)c1ccc(SCC(N)=O)cc1 +CC(=O)c1c(C)[nH]c(C(=O)N(C2CC2)C2Cc3ccccc3C2)c1C +Cc1cc(C)n2nc(NCc3c(Cl)cccc3Cl)nc2n1 +CC(=O)NCc1nc(-c2ccc(-c3csc(C)n3)cc2)no1 +Cc1ccc2c(c1)OCC(=O)N2CC(=O)Nc1ccccc1Cl +CSc1ccc(OC(C)C(=O)NCC(C)(O)c2ccccc2)cc1 +O=C(NCCNc1ccc(-n2cccc2)nn1)c1ccccn1 +COC(=O)C1(N(C)C(=O)CCc2cnn(C)c2)CCCCC1 +Cc1cc(NC(=O)C(C)Sc2nc(CCC3CCCC3)n[nH]2)on1 +O=C1CC2(CCN(C(=O)C3CCOCC3)CC2)CN1 +COc1ccc(CC(=O)Nc2ccc(F)c(Cl)c2)cc1OC +C=CCNC(=O)c1ccccc1NC(=O)Cc1ccc(Cl)cc1 +CCC(C)C(=O)Nc1cccn(Cc2ccccc2)c1=O +Cn1cn[nH]c1=NC(=O)c1ccc(Br)cc1 +CC(C)(C)CC(=O)Oc1ccc2ccc(=O)oc2c1 +NC(=O)CC1CCN(C(=O)NCCCc2ccccc2)CC1 +CCn1cc(CNC(=O)C2CCCN(S(C)(=O)=O)C2)c(C)n1 +C=CCNC(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +O=C(NC1CC1)C1CCCN1C(=O)CCc1ccc(F)cc1 +Cc1cccc(-n2c3c(cc(C#N)c2=O)C(=O)CCC3)c1C +CCN(Cc1ccccc1Cl)C(=O)CNC(=O)CNC(C)=O +COCc1ccc(C(=O)Nc2cccc(-n3cnnc3)c2)cc1 +COc1ccc2cc(C(C)N3CCOC(C(N)=O)C3)ccc2c1 +CCOC(=O)CC1C(=O)n2ncc(-c3ccccc3)c2N=C1C +COCCN(C)C(=O)NC1CCC2(CC1)OCCO2 +COc1cc(NC(=O)C2CCCN(c3ncccn3)C2)cc(OC)c1 +CNS(=O)(=O)c1ccc(SC)c(C(=O)N2CCC(C)CC2)c1 +COC(=O)c1cccc(CCNC(=O)OC(C)(C)C)c1F +CCCNC(=O)CN(C)C(=O)NCc1nncn1CC +CS(=O)(=O)N(CCOc1cccc(F)c1)c1cccc(C#N)c1 +O=C(CNC(=O)C1CC1)Nc1ccc(Oc2ccc(F)cc2)cn1 +Cn1ncc2c(N3CCN(C(=O)c4cccnc4)CC3)ncnc21 +Cc1ccc(S(=O)(=O)NCc2cn[nH]c2)cc1C(N)=O +CCN(Cc1ccccc1Cl)C(=O)NCCC(=O)N(C)C +COc1ccnc(NC(=O)c2cc(-c3ccccc3Cl)[nH]n2)c1 +CCOc1ccc(C2Nc3ccccc3C(=O)N2C(C)C)cc1 +CN(C)C(=O)CN(C)C(=O)CCc1cccc(N)c1 +CC(=O)c1c(F)cccc1NCc1ccccc1Cn1cncn1 +Cc1nc(N)nc(N(C)c2ccccc2)c1Br +COc1ccc(CNC(=O)NCC2(c3ccccc3F)CC2)cc1F +COc1cccc(C(=O)Nc2cc(-c3nnco3)ccc2C)c1F +CCOc1ccccc1NC(=O)c1ccc(C(=O)N(C)C)cc1 +N#Cc1cc2cc3c(cc2c(-c2ccncc2)n1)OCCO3 +CCC(CO)Nc1ccc(NC(=O)c2cccnc2)cn1 +O=C(OCC(F)F)c1cnn(-c2ccccc2Cl)c1 +Cc1nn(C)c2[nH]c(C(=O)Nc3ccc(F)c(Cl)c3)cc(=O)c12 +Cc1cccc(OCCNC(=O)CCc2ccco2)c1 +Cc1cc(N2CCC(C(=O)NC(C)(C)C)C2=O)ccc1F +COc1cc(OC)c(NS(=O)(=O)c2cccc(F)c2)cc1Cl +COc1ccc(OC)c2c1CCNC2CNC(C)=O +O=C(NCCC(=O)N1CCCC1)Nc1cccc(Cl)c1Cl +CCNC(=O)c1cccc(CNC(=O)Nc2ccc(Cl)c(F)c2)c1 +Cc1sc(=O)n(CC(=O)NC2CCC(c3ccccc3)CC2)c1C +CCc1n[nH]c(C2CN(C(=O)c3c(CC)noc3C)CCO2)n1 +O=C(Cn1ccnc1)Nc1ccccc1Sc1ccccc1 +CC(=O)c1sc(Nc2ccc3c(c2)OCCO3)nc1C +NC(=O)C1CCN(C(=O)c2occc2-c2ccccc2)C1 +O=C(Nc1ccc(F)cc1)c1nccn1-c1ccccc1 +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)Nc1cccnc1 +Cn1cnc(CNC(=O)NC2CCCN(c3ccccc3Cl)C2)n1 +COc1ccccc1NC(=O)N1CCCC(CNC(=O)C(C)C)C1 +CC(Cn1cccn1)NC(=O)N1CCCC(c2nncn2C)C1 +O=C(NCc1ccccc1)c1ccc(Nc2ncccn2)cc1 +CCc1nnc(CNC(=O)Nc2ccc(OC)nc2OC)o1 +CC(C)C(=O)Nc1ccc(Cl)c(C(=O)NC2CCCC2)c1 +CC1CC(=O)N(CC(=O)N2CCCCC2)c2ccccc2S1 +NC(=O)c1ccccc1OCC(=O)Nc1cccc(N)c1 +CN1C(=O)CCc2cc(NC(=O)OCc3ccccc3)ccc21 +CN(C)S(=O)(=O)CCCN1CCOC(Cn2cncn2)C1 +CCc1nn(-c2ccc(Cl)cc2)c2c1CNCC2 +N#Cc1cc(C2NCCc3cc(F)c(F)cc32)ccc1F +CC(C)n1ncc2c1N=C(O)CC2c1ccc(S(C)(=O)=O)cc1 +C=CCOc1ccc(C2Nc3ccccc3C(=O)N2CCOC)cc1 +Cc1cc(=O)c(C(C)(C)O)nn1-c1ccc(F)cc1 +C=CCN(CCc1ccccc1)C(=O)NCc1ncn(C)n1 +O=S(=O)(NCCCn1cccn1)c1ccc2c(c1)CCCC2 +C=CCn1c(C2CC2)nnc1S(=O)(=O)C(CC)c1ccccc1 +Cc1cccc2c1CNCC2C(=O)NC(C)(C)CO +O=C(Nc1cccc(O)c1)c1c[nH]c2c(C(F)(F)F)cccc2c1=O +CCN1CC(C(=O)NCCc2nnc(C)s2)CCC1=O +CCOC(=O)c1[nH]c2ccccc2c1NC(=O)Cc1cccs1 +Cc1c(C(=O)N(C)CCC#N)oc2c1ccc1ccccc12 +CN(Cc1cnc(-c2cccnc2)s1)CC1CCCCO1 +CC(C)CNC(=O)c1ccc(Br)cc1 +CC(C)n1c2ccccc2n2c(-c3ccc(N)cc3)nnc12 +CCNc1nn(-c2ccc(OC)cc2)c2c1C(=O)CC(C)(C)C2 +COc1cccc(-c2noc(COc3ccc(C)cn3)n2)c1 +O=C(NC1CCCCCC1)NC1CCC(O)CC1 +COc1cccc(C(=O)N(C)C2CCCc3c2cnn3C)c1F +CC(C)Nc1nc(NC(C)C)nc(Oc2ccc(=O)n(C)n2)n1 +CCn1nc(C)c(S(=O)(=O)Nc2ccc(C(C)=O)cc2)c1C +O=C(NCCc1ccc(O)cc1)c1ccc2c(c1)OCO2 +COc1cc(C)c(C(=O)N(C)CCOc2ccccc2)cc1OC +COc1ccccc1N1CCN(C(=O)c2cccc(OC)c2O)CC1 +CN(CC(F)(F)F)C(=O)c1cc2cc(Cl)ccc2[nH]1 +Cc1cc(C(=O)Nc2cccnc2)c(C)n1C1CC1 +N#CC(C(=O)Cn1c(=O)cnc2ccccc21)c1nc2ccccc2[nH]1 +Cc1cccc(C(=O)N2CCN3C(=O)C(CO)NC(=O)C3C2)c1 +COc1ccccc1CNC(=O)c1cc(C)nc2c1cnn2C(C)C +N#Cc1nc(COc2ccccc2Cl)oc1NCC1CCCO1 +Cc1cc(-n2c(C)cc(C(=O)NC3(C)Cc4ccccc4C3)c2C)no1 +CC(C)c1n[nH]c(SC(C)c2nc(-c3cccs3)no2)n1 +COCCN(C)C(=O)c1ccc(Cn2cccn2)cc1 +CC(C)CNC(=O)N1CCCC(C(=O)NCC2CC2)C1 +OCCc1cn(-c2ccc(OC(F)F)cc2)nn1 +NCC#Cc1ccc(CN2CCCOCC2)s1 +COc1ccc(NC(=O)c2cnc(N3CCC(C)CC3)nc2N)cc1 +CSc1cccc(NC(=O)CSc2ccc3nnc(C)n3n2)c1 +Cc1noc(C)c1Cn1nnc(CO)c1CC(C)C +CCOc1ccc(C(=O)NCc2ccc(-n3cccc3)cc2)cc1 +O=C(CCCc1cn[nH]c1)N1CC2CCC(C1)N(CC1CCC1)C2=O +O=S(=O)(c1cc(F)ccc1Cl)N1CCC(n2ccnc2)CC1 +CCC(=O)N1CCCCC1c1nc(N(C)C)ncc1-c1cc(C)no1 +C=CCN(Cc1ccccc1)C(=O)c1cccc(C)c1 +CCc1ccc(CCNC(=O)c2ccncc2F)cc1 +O=C(Nc1ccc(C(=O)OCC2CCCCO2)s1)c1ccco1 +O=C(c1scnc1C1CC1)N1CCCC(N2CCCC2=O)C1 +COc1cccc(C(=O)OCC2COc3ccccc3O2)c1F +Clc1cccc(CNc2ncnc3c2cnn3-c2ccccn2)c1 +CNC(=O)c1cnc(COc2cccc(C(C)C)c2)nc1N +CN(C(=O)c1ccc(-n2cccn2)cc1)c1cccc2ncccc12 +Cc1csc(CNC(=O)NC(C)Cc2c(F)cccc2F)n1 +Cc1ccc(NC(=O)Cn2nnc(COc3ccccc3)n2)cc1F +COc1ccc(CC(=O)Nc2nc(-c3ccc(C#N)cc3)cs2)cc1 +CC(=O)NCC1CN(C(=O)c2cccc(C(F)(F)F)c2F)CCO1 +COc1ccccc1-c1cc(C(C)(C)O)c(=O)n(C)n1 +CCc1onc(C)c1NC(=O)c1ccc2c(c1)CCCC2 +CC1CC1NC(=O)Nc1ccc(Oc2cccnc2)nc1 +Cc1nn(C)cc1CNC(=O)Nc1ccc(Cl)cc1 +COc1ccc(C2NCCc3c(C)cc(F)cc32)cc1O +COc1ccc(-c2cccc(N(C)C)c2)n2nc(N)nc12 +Cn1c(C2CC2)nc2cc(NC(=O)Cc3cccc(F)c3)ccc21 +CN1C(=O)CCC2(CNC(=O)c3ccnn3C)CCCC12 +c1ccc2c(c1)SCCN2Cc1noc(C2CC2)n1 +CC(C)(C)c1ccc(OCc2nnc(SCC(N)=O)n2N)cc1 +CC(c1ccccn1)N(C)C(=O)c1cccc(S(C)(=O)=O)c1 +Cc1cccc(C(C)C)c1NC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1ccc(-c2cc(C(=O)NCc3nnc4n3CCC4)[nH]n2)o1 +CCCCCNC(=O)c1onc(-c2ccccc2C)c1N +O=C(NCC1CCCCC1)C1CCCN(c2cnccn2)C1 +CC(=O)c1ccc(NC(=O)NCc2nnc3ccccn23)cc1 +Cc1ccc2c(c1)c(=O)c(C(=O)NCc1ccccc1F)nn2C +CSc1nsc(NC(=O)C(C)NC(=O)c2ccco2)n1 +CC(C1CC1)N(C1CC1)S(=O)(=O)c1cn[nH]c1 +c1ccc(-c2cc(CNc3nccc(-c4ccccn4)n3)on2)nc1 +Cc1ccc(F)cc1NC(=O)COc1ccccc1N +CC(c1ccco1)N(C(=O)c1c[nH]c2cccc(F)c12)C1CC1 +CCCCCNC(=O)C(N)c1cc(F)ccc1C +CCNC(=O)C(C)NC(=O)c1ccc2ccccc2c1 +CCN(CC)C(=O)CSc1nnc(-c2cccc(C)c2)n1CC +CCc1cc(=O)[nH]c(N2CCc3ccccc3C2)n1 +COc1cccc(NCC(=O)N2CCC(C)CC2)c1 +O=C(CCc1cccnc1)NCc1cccc(Cn2ccnc2)c1 +O=C(NCCc1nccs1)C1CCN(c2ccccc2)C1=O +CCN(CC(C)C#N)C(=O)c1ccc(COc2ccc(C#N)cc2)o1 +Cc1nnnn1-c1cccc(NCc2c[nH]nc2-c2ccccc2F)c1 +N#CC(Cc1ccncc1)c1cccc(Br)c1 +N#Cc1ccc(C(=O)Nc2cnn(-c3ncccn3)c2)cc1 +CN(CC(=O)Nc1cccc(Cl)c1N(C)C)C(=O)OC(C)(C)C +COCc1cc(N2CCC(Cc3nc(C)no3)CC2)ncn1 +COc1cc(NC(=O)c2cc(C)cc(C)c2)cc(OC)c1OC +CCc1nc(Cn2cnc(C3CCC3)cc2=O)cs1 +O=C1OCC2Cc3ccccc3C(c3ccccc3)N12 +Cc1nn(C)c(C)c1C(=O)Nc1cccc(C#N)c1 +COCCOc1ccccc1NC(=O)CC1CC2CCC1C2 +Cn1nc2n(c1=O)CCN(C(=O)c1ccc(-n3ccnc3)cc1)C2 +COc1ccc(CNC(=O)N2CCC(n3cccc3)CC2)c(OC)c1 +Fc1ccc2c(c1)nc(N1CCCC1)c1nccn12 +CCOc1ccccc1N1CC(C(=O)Nc2cc(C)n[nH]2)CC1=O +CC1(C)CN(CC(=O)Nc2nccs2)c2cc(N)ccc2O1 +Cc1ccoc1C(=O)NCC(C)(CC(C)C)NC(=O)c1occc1C +O=C(CSc1nnc(COc2ccccc2)o1)Nc1ccccc1 +C=C(C)COc1ccc(C(=O)NCc2ccncc2)cc1 +CCOCCCNC(=O)c1cc(C)nc(SC)n1 +CCc1ccc(NC(=O)Cn2cnc(C(C)C)cc2=O)cc1 +CC(C)(C)c1[nH]c(=NS(C)(=O)=O)ccc1OC1CC1 +CCN1CCN(C(=O)c2nc(-n3nc(C)cc3C)ccc2Cl)CC1 +Nc1ncnc(Nc2ccc(OC(F)(F)F)cc2)n1 +CCc1ccc(C(=O)NC2CCCc3[nH]c(=O)c(C(N)=O)cc32)cc1 +CC(C)N(C)C(=O)CCCc1nc(-c2cccs2)no1 +O=C(Nc1ccc(Cl)cn1)C1CC1c1ccc(F)cc1 +CCOC(=O)CN(C)C(=O)C(C)(C)c1ccccc1 +COc1ccc2c(c1)nc(CC#N)n2Cc1ccccc1F +O=C(c1cccs1)N1CCN(CC2CCCCC2)CC1 +CC(=O)Nc1ccc(S(=O)(=O)CC(=O)N(C)C2CC2)cc1 +N#Cc1ccc(-c2csc(C(C#N)C(=O)c3cccs3)n2)cc1 +Cc1nnc(-c2cc(NC(=O)C3CC3)c(C)s2)o1 +CCC(C)NC(=O)c1ccc(NC(=O)c2[nH]nc3c2CCCC3)cc1 +CS(=O)(=O)c1ccc(OCCCN2CCOCC2C2CC2)cc1 +COCCN1C(=O)C2CCC1CN(C(=O)c1ccc3[nH]cnc3c1)C2 +Cc1nc(N)nc(N2CCN(c3ccccc3)CC2)n1 +Cc1ccc(N2CCCN(Cc3cnn(C(C)(C)C)c3)CC2)nn1 +N#CC(NC(=O)c1[nH]ncc1Br)c1ccc(Cl)cc1 +Nc1ccccc1-c1nnnn1CCC(F)(F)F +Cn1cnc(CNC(=O)N(Cc2c(F)cccc2Cl)C2CC2)n1 +NC(=O)Cc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 +CCN(C(C)=O)C1CCN(C(=O)c2ccnc(NC)c2)C1 +O=C(NCc1ccncc1)c1ccc(NC(=O)c2ccccc2)cc1 +Cc1cc(SCC(=O)Nc2ccc(Br)cc2)ncn1 +O=C(CCc1ccc(OC(F)F)cc1)NC1CC1 +CC(C)c1noc(CCNC(=O)c2ccn(C)c(=O)c2)n1 +CS(=O)(=O)c1ccc(C(=O)Nc2ccc(OC(F)F)cc2)cc1 +O=C(CSc1nnnn1C1CCCC1)NCC(=O)NC1CC1 +COc1cc(Br)c(NC(=O)CC(C)C)cc1OC +COC(=O)CN(Cc1nc(N)nc(N)n1)C(C)C +COc1nn(C)cc1-c1nnc(SCCC(C)C)n1C +N#CCn1c(C2CCCCC2)nc2cc3c(cc21)OCCO3 +CCCn1nnc(NCc2cc(Cl)cc(Cl)c2OC)n1 +O=C(CSc1ccc(-c2ccco2)nn1)NCc1ccccc1 +CCOc1cccc(CNC(=O)c2cccnc2OC)c1 +N#Cc1c[nH]c(C(=O)N2CCc3c(Br)ccc(F)c3C2)c1 +Cc1cccc(CCNC(=O)NC(C)c2c(C)nn(C)c2C)c1 +O=C(CC1CCCCO1)Nc1cccc(Cn2ccnc2)c1 +CC(NC(=O)c1ccncc1)c1ccc(-n2cccc2)cc1 +O=C(Cc1ccc[nH]1)Nc1ccc(F)cc1OCC1CC1 +Cc1ccc(CC(=O)N2CCN(C(=O)c3ccncc3F)CC2)cc1 +COc1cc2c(cc1O)C(c1c(F)cccc1F)NCC2 +CC(=O)N1CCCC1C(=O)NC(C)CCc1ccc(F)c(F)c1 +CCCN(CCO)C(=O)c1csc2ccccc12 +C#CCOC(=O)c1cc(S(=O)(=O)N(C)C)ccc1Cl +Fc1ccc(C=CCN2CCOC3(CCOCC3)C2)cc1 +CCS(=O)(=O)NCCS(=O)(=O)NC1(C)Cc2ccccc2C1 +CC(C)COC(=O)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +CC1CS(=O)(=O)N(c2ccc(C(C)(C)C)cc2)C1=O +CC(Oc1ccccc1)C(=O)N1CCN(CCO)CC1 +CCCc1noc(CNc2cccc(NC(C)=O)c2C)n1 +CCCCNC(=O)CSc1ccc(F)cc1N +CC(=O)NC1CCN(S(=O)(=O)c2ccccc2C#N)CC1 +O=C(NCC(O)C1CCCCC1)Nc1ccc2c(c1)OCO2 +CC(C)COC(C)C(=O)Nc1cccc2cn[nH]c12 +CC(NC(N)=O)C(=O)Nc1ccccc1CN1CCc2ccccc21 +COc1cccc(-c2noc(CNc3ccc(F)c(C(N)=O)c3)n2)c1 +Cc1ncsc1C(=O)NCC1CCCC(C)C1 +COc1cc(F)c(C(C)NC(=O)c2cccnc2C)cc1OC +Cn1c(=O)ccn(CC(=O)N2CCOc3ccc(F)cc32)c1=O +CC1CCN(C(=O)c2ccccc2C(=O)c2ccccc2)CC1 +Cc1ccccc1COC1CCN(C(=O)C2(c3ccccc3)CC2)CC1 +CCc1n[nH]c(C2CN(C(=O)c3ccon3)CCO2)n1 +NC(=O)CNC(=O)Cn1cccc(C(F)(F)F)c1=O +O=C(Nc1cccc2cnccc12)C1CCN(c2cnccn2)CC1 +Cn1nc2n(c1=O)CCN(CCC(=O)Nc1cccc(F)c1)C2 +Cc1oc(N)c(C#N)c1-c1ccc2c(c1)CCC(=O)N2 +COC1CCCCC1OC(=O)c1cc(NC(C)=O)ccc1F +COC(=O)c1cnc(NC(=O)c2ccnc(C)n2)s1 +O=C(CC1CCCC1)N1CCc2ccc(O)cc2C1 +CCn1nc(NC(=O)c2ccncc2)c2cc3cc(C)ccc3nc21 +CC(NC(=O)Cc1c[nH]c2ccc(F)cc12)C(=O)NCc1ccco1 +CN(C)C(=O)c1ccc(OCc2ccc(F)cc2F)cc1 +CCOC(CC)C(=O)Nc1ncc(C(N)=O)s1 +CCc1onc(C)c1NC(=O)C1CCCCN1C(=O)c1ccco1 +CC(C)(C)OC(=O)NCCNC(=O)c1ccc(-c2ccco2)[nH]c1=O +N#Cc1cc(NCc2nnc3n2CCCC3)nc2ccc(Cl)cc12 +CCN(CC)S(=O)(=O)NC(C)c1ccc2c(c1)OCO2 +CCOC(=O)N1CCN(Cc2cn3c(C)cc(C)nc3n2)CC1 +CC(C)C(Sc1ncn(-c2ccccc2)n1)C(=O)NC(C)(C)C +COc1ccc(O)c2c1C(c1ccnnc1)NCC2 +CCCNC(=O)Cn1c2c(c(=O)n3ncnc13)CCC2 +N#Cc1ccc(N2CCN(C(=O)C3CCCc4ccccc43)CC2)nc1 +CC(C)c1cc(CNC(=O)CCc2nnc(-c3ccsc3)o2)on1 +CCC(C)NC(=O)NC(C)(C(F)(F)F)C(F)(F)F +CCN(CC)S(=O)(=O)N1CCCC(C(N)=O)C1 +CCCc1cc(C(=O)N2CC(Oc3ccc(F)cc3)C2)n(C)n1 +CN(Cc1ccccc1)C(=O)c1cc2n(n1)CCCO2 +COCCOc1ccccc1NC(=O)NCc1ccc(F)cc1 +COc1ccnc(NC(=O)c2ccccc2SCC2CCCO2)c1 +CC(CNC(=O)Cn1cccnc1=O)N1CCc2ccccc21 +O=C(c1c[nH]c2cccnc12)N1CCc2ccccc21 +CC1CC(=O)Nc2ccccc2N1C(=O)c1cnccn1 +CCc1n[nH]c(SCC(=O)N2CCN(c3ccccc3F)CC2)n1 +COc1nc(-c2ccco2)nnc1-c1ccccc1 +C#CCN(Cc1ccc(C)cc1)Cc1nc2c(cnn2C)c(=O)[nH]1 +CC(=O)c1ccc(NCC(=O)N2CCCCCC2)cc1 +CCN(CC)C(=O)C1CC(NC(=O)c2cccc(N(C)C)c2)CN1C +Cc1ccc(CNC(=O)C2CC3CCC2O3)c(OCC2CC2)c1 +Cc1ccc(NC(=O)COC(=O)CCn2c(C)csc2=O)cc1 +Cc1ccc(C)c(CC(=O)N2CCOc3ccncc32)c1 +CN=S(=O)(CC1(O)CCCC12C=CCO2)c1ccccc1 +Cc1cc(C)c2c(N)c(C(=O)c3ccc[nH]3)sc2n1 +CC(=O)c1cccc(S(=O)(=O)N(C)Cc2csc(C)n2)c1 +Cn1ccnc(NC(=O)c2nc(-c3ccccc3)oc2C2CC2)c1=O +COc1ccc(C(=O)OCC(=O)Nc2ccc(C)cc2C)cc1N +N#CCSc1nnc(N)n1CC(=O)Nc1nc2c(s1)CCCC2 +CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2F)c1 +O=C(c1cc(Cl)c[nH]1)N1CCN(CC(O)c2ccccc2)CC1 +Cc1ccccc1C(O)CNC(=O)NCc1ccc2c(c1)OCCO2 +CC(C)(C)CCOC(=O)c1cc(S(C)(=O)=O)ccc1Cl +O=C(Nc1ccc(F)cc1)N1CCN(c2ccc(O)cc2)CC1 +O=C(Nc1ccc(-n2nccc2C(F)(F)F)cc1)Nc1cn[nH]c1 +N#Cc1cccc(CNC(=O)Cn2ccccc2=O)c1 +CNC(=O)C1CN(S(=O)(=O)c2ccc(C)cc2)c2ccccc2O1 +CCN(CC(=O)NC(C)C)S(=O)(=O)N1CCCCCC1 +CCC1CCc2sc(C(=O)NCc3ccccn3)cc2C1 +CCC(=O)Nc1ccccc1C(=O)Nc1cccc(Cl)c1 +CSc1ccc(Cl)cc1NC(=O)NCc1nncn1C +COCCN1C(=O)CCc2c(C)nc(-c3cccnc3)nc21 +Cc1nc(N(C)C)ncc1C(=O)NCCNC(=O)c1cccnc1 +CCn1cc(NCc2ccc(OC)c(COC)c2)cn1 +COC(=O)C(C)CN(C)S(=O)(=O)c1ccc(C(C)C)cc1 +CCNC(=O)NC(C)c1cccc(NS(C)(=O)=O)c1 +O=C(Nc1ccccc1C(=O)NCC(F)(F)F)c1ccccc1 +Cc1nc(NCC(O)COc2c(C)cccc2C)c2cnn(C)c2n1 +CC(c1ccccc1F)N1CCN(C(=O)C2CCC(=O)N2)CC1 +Cc1noc(-c2cccnc2N2CCCC(NC(=O)C(C)C)C2)n1 +Cc1ccccc1OCCC(=O)NCCc1cccs1 +CCCCC(NC(N)=O)C(=O)Nc1ccc(C)cn1 +COc1cc2c(cc1OC)C(c1c(F)cccc1Cl)CC(=O)N2 +COc1ccc(C(=O)Nc2nnc(C)c(C)n2)cc1 +COc1ccc(NC(=O)Nc2cccc(C(C)=O)c2)c(OC)c1 +CCNC(=O)C1CC=CCC1C(=O)Nc1ccc(Cl)cc1 +CC(C)n1[nH]c(=O)c2c1N=C(O)CC2c1ccc(Cl)cc1Cl +COCCOC(=O)c1csc(-c2ccccc2)n1 +Cc1cc2nc(NCc3ccccn3)sc2cc1C +CC(C)CCn1nnc(CO)c1-c1ccc2c(c1)OCO2 +Nn1c(CCCc2ccccc2)nc2sc3c(c2c1=O)CCC3 +Cc1cccc(NC(=O)COc2ccc(CO)cc2)c1 +Nc1cccc(-c2csc(=O)n2CC(=O)N2CCOCC2)c1 +O=C(Nc1cccnn1)N1CCc2cc(F)ccc2C1 +Cc1ccoc1C(=O)OCCN1CCN(C(=O)C2CCC2)CC1 +Cc1noc(C)c1CC(=O)NCc1cc(-c2ccc(Cl)cc2)on1 +O=C(Nc1ccc(C2CC2)nn1)C1CN(Cc2ccccc2)CCO1 +CCC1C(=O)NCCN1C(=O)c1cc(F)cc(Br)c1 +CCCN(C)C(=O)c1c(C)n(CCC)c2ccc(OC)cc12 +CCC(=O)NC1CCCN(C(=O)Nc2ccc(F)cc2)C1 +COCC1(C(=O)NCc2n[nH]c(-c3ccccc3)n2)CCC1 +CCCCOCCN1CCN(c2ncccc2C#N)CC1 +N#Cc1cccc(NC(=O)NC(CCO)C2CC2)c1 +COc1ccc(Cl)cc1C(=O)CCCC(=O)NC(C)C +COc1ccccc1Sc1ccccc1C(N)=O +CC(C)c1c(C(=O)OCC(N)=O)cnn1-c1ccc(F)cc1 +NC(=O)c1ccc(NC(=O)c2ccc(=O)n(-c3ccccc3)n2)cc1 +CCCOc1ccc(OCc2cccc(C(N)=O)c2)cc1 +Cn1cc(Cl)cc1C(=O)N(CCO)C1CCCCC1 +CCNC(=O)CCc1ccccc1Br +Cc1nn(C)c(C)c1C(=O)Nc1ccccc1C(F)(F)F +O=C(CSc1nnnn1C1CC1)OCC1CCCCC1 +CCCOC(=O)CN1C(=O)C(C)Oc2c(OC)cc(CO)cc21 +Cc1cnn(Cc2cccc(Br)c2)c1N +O=C(NCCCCn1ccccc1=O)c1n[nH]c2ccccc12 +CC(C)(C)c1cc2nc(-c3ccncc3)cc(O)n2n1 +CSc1ccc(OC(=O)c2ccc(Cn3ccccc3=O)o2)cc1 +CCCCc1nnc(NC(=O)c2cnn(C)c2-n2cccc2)s1 +COCCn1cnnc1SC(C)C(=O)N1CCCCCC1 +CCCn1cc(Br)cc1C(=O)N(C)CC(O)COC +N#Cc1ccc(F)c(COC(=O)c2c[nH]c3ccccc23)c1 +Cc1cc(CNC(=O)c2ccccc2OCc2c(C)noc2C)on1 +COc1ccc(CC(C)CNC(=O)c2cn(C)nc2C)cc1 +CC1CN(Cc2cc3ccccc3[nH]c2=O)c2ccccc21 +CCc1nc(C(=O)NCc2c(CC)noc2CC)c[nH]1 +CCn1cnnc1CNC(=O)C1CC(=O)N(c2cccc(OC)c2)C1 +CCC1c2ccsc2CCN1C(=O)c1cnco1 +CN(C)C(CNC(=O)c1ccc2c(c1)CCC(=O)N2)c1cccs1 +O=c1cc(C2NCCc3cccc(F)c32)c2ccccc2[nH]1 +Cc1oc2ncn(Cc3c(F)cccc3Cl)c(=O)c2c1C +OC(C=Cc1ccc(Cl)cc1)(Cn1cncn1)c1ccncc1 +CCc1nc(C)c(C(=O)NCCN2CC(C)OC(C)C2)s1 +COc1ccccc1CCNS(=O)(=O)Cc1ccccc1 +CC(C)C(C)NC(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +O=c1ccc(-c2ccccc2)nn1CCS(=O)(=O)c1ccccc1 +CN(CCC#N)C(CO)c1cccc(Br)c1 +CC1CCCCC1N(C)C(=O)CSc1nnnn1Cc1ccco1 +O=C(CC(F)(F)F)N1CCc2ncnc(C3CC3)c2CC1 +Cc1nc(N2CCN(Cc3ccnn3C)CC2)sc1C +Fc1ccc(-c2nnc(NCc3ccco3)s2)cc1 +COc1cccc(CC2(CO)CCN(S(=O)(=O)N(C)C)CC2)c1 +COC(=O)c1nn(C)c(N)c1-c1ccc(OC)c(C(C)C)c1 +CCN(C1CCCC1)S(=O)(=O)c1ccc(C)s1 +CN(C)c1ccc(NC(=O)c2ccc(N3CCOC3=O)cc2)cn1 +CC(C)N(C)C(=O)NC1CCN(c2ccccc2Cl)C1=O +Cn1cc(CCCSc2nnc(C(F)(F)F)n2N)cn1 +Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)C1(C#N)CCCC1 +CC(CO)C(C)NC(=O)NC1CCN(CC(F)(F)F)C1=O +COc1cccc(C(O)CCC(=O)N2CCC(C)CC2)c1 +COC(=O)CNC(=O)c1c[nH]c2c(F)cccc2c1=O +CC(=O)c1ccccc1OCC(=O)N1CCN(C)CC1 +Cc1ccc(C(=O)c2ccccc2C(=O)NCc2ncn(C)n2)cc1 +COc1ccc(C(=O)Nc2ccc(-n3ccnc3)nc2)cc1OC +Cc1ccccc1OCCCN1C(=O)C(=O)c2ccccc21 +Nc1cc(-c2ccc(Br)cc2)nn1CCO +COc1cccc(CC(=O)NCC2COc3ccccc3C2)c1 +CC(C)Nc1nnc(-c2cc(C(C)(C)C)nn(C)c2=O)s1 +CC1CCCC(NC(=O)NCC(C)(C)c2ccncc2)C1 +O=S(=O)(NCCCO)c1ccc2c(c1)CCC2 +CC(=O)Nc1cccc(OCC(=O)NC(C)(C)C)c1 +CN(C)C(=O)c1cccc(S(=O)(=O)N(C)C2CCCCC2)c1 +CN(C)c1cccc(COc2ccccc2C#N)c1 +COc1cccc(C2NCCc3ccc4[nH]ccc4c32)c1 +CCS(=O)(=O)NCC1CCN(c2cnccn2)CC1 +CC1(O)CC2C(CC1OC(=O)c1ccco1)C2(C)C +Cc1cc(C)cc(NC(=O)CCn2c(=O)[nH]c(=O)c3ccccc32)c1 +CCc1ccc(-n2cc(C(=O)NCc3cccc(OC)c3)nn2)cc1 +Cc1ccc(Cl)cc1-n1cc(C(=O)NCc2ccccn2)nn1 +CNC(=O)C(C)CN(C)C(=O)Nc1cc(Cl)ccc1N(C)C +COc1ccc(C)cc1-c1c(C2CC2C)noc1N +O=C(c1cccc(-n2cccn2)n1)N(Cc1ccc(F)cc1)C1CC1 +O=C(COCC1CCCCO1)N1CC2CC3CC(C2)CC1C3 +CCOc1ccccc1CNC(=O)C1COCCO1 +COc1ccc(CCc2nc(C(C)(C)NC(C)=O)no2)cc1 +O=C(CCc1ccccn1)Nc1ccc(Cl)cc1F +COC(=O)CSc1nnc(-c2ccc(Br)cc2)n1N +COCC(=O)Nc1ccccc1N1CCOCC1 +CCn1nc(C)c(NCc2cnc(C3CCCC3)s2)c1C +CCc1csc(Sc2nc3ccc(N)cc3[nH]2)n1 +CCc1cccc(C)c1NC(=O)CCN1CCOC1=O +Cc1ccc(NC(=O)c2ccc(-n3c(C)nnc3C)cc2)cc1F +Cc1ccc(OC2CCN(S(=O)(=O)c3cccs3)CC2)nn1 +Cc1c(C(=O)N2CCC(C)CC2C)nnn1-c1cccc2ncccc12 +Cc1cccc2cc(C(=O)N3CCCC(n4cccn4)C3)oc12 +CN(C)C(C(=O)N1CCC(CCO)CC1)c1ccccc1F +CN(C)C(=O)c1ccc(C(=O)OCCn2cccn2)cc1 +O=C(NCc1cccc(CN2CCCC2=O)c1)c1ccc(F)cc1 +CS(=O)(=O)c1ccc(OCCNCC(F)(F)F)cc1 +Cc1ccn(C(=O)c2ccnn2C)c(=NC(=O)c2ccnn2C)c1 +Cc1cc(NC(=O)C2CC(=O)N(C)C2c2ccc(F)cc2)no1 +COc1ccc(-c2nccn3cc(C(=O)NC(C)C)nc23)cc1 +CC(=O)NCCCNC(=O)Nc1cc(F)ccc1C +Cn1cc(-c2c(C#N)c(N)nc3c2CCc2[nH]ccc2-3)cc1C#N +O=C(NCc1ccncc1)c1cc2cccn2cn1 +COCCCNC(=O)Nc1cccn(Cc2ccccc2)c1=O +COCCn1cc(NC(=O)c2ccnc(OC3CCC3)c2)cn1 +N#Cc1nc2cc(F)ccc2n1Cc1cccnc1 +CNc1ccc(S(=O)(=O)NCc2nc(C)cs2)cc1 +COc1cccc2oc(-c3cc(N)ccc3Cl)cc(=O)c12 +CCOC(=O)COc1cc(Br)c(C#N)cc1OC +Nc1ccc(Cl)c(NC(=O)COc2ccccc2)c1 +Cc1nn(C)c2nc(N(C)CC3CCCCO3)sc12 +N#Cc1cccc(-c2nnc(Cn3cc(-n4cccc4)cn3)o2)c1 +CC(COc1ccccc1C(F)(F)F)NC(=O)CC(F)(F)F +COCCNC(=O)Cc1coc2cc(C)c(Cl)c(C)c12 +Nc1nc(-c2ccccc2)ccc1C(=O)NCc1cccnc1 +CCCCCNS(=O)(=O)c1cccc2cnccc12 +COc1ccc(CN2C(=O)OCC2C(=O)NCCn2cccn2)cc1 +CCCNC(=O)Cn1c(-c2ccco2)nc2ccccc21 +O=C(Nc1cc(F)cc(Br)c1)NC1C=CC(CO)C1 +CN(C)c1cc(C(=O)NCCc2ccccc2)nc(N(C)C)n1 +N#CC(NC(=O)CNC(=O)c1cccc(F)c1)c1ccc(F)cc1F +CC(=O)Nc1ccc2c(c1)nc1n2C(CNC(=O)NC(C)C)COC1 +CC(C)Sc1ccccc1C(=O)Nc1ccc2c(c1)OCCO2 +CCOc1cc(N2CCN(S(=O)(=O)CC)CC2)nc(C)n1 +CCc1nnc2n1CCN(CC(=O)Nc1ccnn1C(C)C1CC1)C2 +CC(C)OCc1ccc(CNC(=O)CN2CCOCC2)cc1 +CC(=O)c1cccc(NC(=O)Nc2ccc(CCO)cc2)c1 +COC(=O)c1[nH]c(=NC(=O)c2c(C)noc2C)sc1C(C)C +Cc1ccc(C(=O)NCC(C)(C)N2CC(C)OC(C)C2)cc1 +COc1ccc(NC(C)=O)cc1NC(=O)c1ccc2ncsc2c1 +CC(NC(=O)CN(C)c1ncnc2[nH]cnc12)c1ccccn1 +CN(CCCc1cnn(C)c1)C(=O)c1cc(-c2ccccc2)on1 +Cc1ccncc1NC(=O)NCc1ccc(OCc2ccccn2)cc1 +NC(=O)Cc1cccc(OCc2ncc(-c3ccccc3)o2)c1 +O=C(CSc1nc2ccccc2o1)N1CCCC1 +CCCCNS(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +O=C(CCNC(=O)c1ccc(F)cc1F)Nc1ccc2c(c1)CCC2 +CC(NC(=O)c1sccc1C1CC1)c1ccco1 +O=C(CNc1ncnc2sccc12)N1CCCCC1 +Cc1nc(C(=O)NC(C)(C)Cc2ccccc2C)cs1 +CSc1ccc(C(=O)NC2(C)Cc3ccccc3C2)cn1 +CCOC(=O)c1csc(NC(=O)CCc2cccc(F)c2)n1 +CC(C)OCCCNC(=O)c1nn(-c2ccc(F)cc2)c2c1CCC2 +CC(CN1CCOCC1)NC(=O)NCc1ccc(-c2ccn[nH]2)cc1 +CC(C)Nc1nc(-c2scnc2C2CC2)cs1 +COc1ccccc1OCc1cc(C#N)ccc1F +CN(CCc1ccccn1)c1ncnc2c1cnn2-c1ccccc1 +CC(C)n1nc(-c2cc3cc(O)ccc3[nH]2)c2c(N)ncnc21 +Cc1cc(NC(=O)c2noc3c2CSc2ccccc2-3)no1 +CC(CNC(=O)N1CC2CC=CCC2C1)N1CCOCC1C +COc1ccc(Cn2cnc3ccccc3c2=O)cc1F +Cc1ncccc1C(=O)N1CCN(C(=O)CCc2ccccc2)CC1 +CCOC(=O)c1cn(-c2nc(C)cc(-c3ccccc3)n2)nn1 +CCCCn1cc(C(=O)NC2CC2)c(=O)c2c(N)cccc21 +COCC(=O)Nc1cc(Cl)c(Cl)cc1Cl +Cc1ccc2c(c1)OCC(=O)N2CC(=O)Nc1ccc(F)cc1C +O=C(Cn1ncc(N2CCCC2)cc1=O)Nc1cc(F)ccc1F +N#Cc1cccnc1NCCNC(=O)C12CC3CC(CC(C3)C1)C2 +CC(C)c1ccccc1NC(=O)CNC(=O)c1ccccc1 +Cc1cc(-n2cc(C(=O)N3CCOCC3)nn2)ccc1F +CCC1CN(C(=O)c2cnc3sccn3c2=O)c2ccccc2O1 +C1=Nc2c(NCc3ccccc3)ncnc2Oc2ccccc21 +CCOc1ccc2oc(-c3ccccc3)c(C(N)=O)c2c1 +CC(=O)N1CCc2nc(NC(=O)C3CC3)sc2C1 +COC(=O)CCC(=O)NC(C)c1oc2ccc(OC)cc2c1C +CCC(C)(NS(=O)(=O)c1cccc(C(C)=O)c1)C(=O)OC +CC(=O)N(C)Cc1cccc(NC(=O)Nc2ccc(C)c(Cl)c2)c1 +COc1cccc(CCNC(=O)c2cc3c([nH]c2=O)CCC3)c1 +Cn1ncc(C(=O)Nc2ccc3c(c2)OCO3)c1-n1cccc1 +Cc1nccn1-c1ccc(NC(=O)c2ccc3c(c2)CCC3)cn1 +COc1ccc(Cl)cc1NC(=O)CSc1nncn1C +CC(=O)NCc1ccc(-c2ccc3ncnc(NCCO)c3c2)cc1 +CCCNC(=O)CCNC(=O)Nc1nnc(CC)s1 +O=C(NCC#CCOc1cccc(C(F)(F)F)c1)c1ccoc1 +O=C1CN(C(=O)Nc2ccccc2Cl)C2CCCCC2N1 +CN(C(=O)CSc1nnc(C(F)(F)F)n1N)c1ccccc1 +Cc1cc(COC(=O)c2ccc(-n3cncn3)cc2)no1 +Cn1nc(CNC(=O)C2CC=CCC2)cc1-c1ccccn1 +Cc1cc(C(=O)N(C(C)C)C2CCC2)c2c(C)nn(C)c2n1 +Cc1ccc(F)c(C(=O)Nc2ccccc2S(C)(=O)=O)c1 +Cc1ccc2c(c1)OCCN2C(=O)CCSc1ccccn1 +C1CCCN(c2nc3nonc3nc2NC2CCOCC2)CC1 +O=S(=O)(NCc1ccoc1)c1cccc2cnccc12 +O=C(NC1CCCCC1)c1ccc(OCC2CCCO2)cc1 +O=C1NCCCC1C(=O)Nc1ccccc1C(F)(F)F +C#CCNS(=O)(=O)c1ccc(C(=O)N(C)C(CC)CC)cc1 +C=CCc1ccccc1OC(C)C(=O)N1CCNCC1 +Nc1cc(=O)[nH]c(SCC(=O)NCC2CCCO2)n1 +O=C(NCc1ccccc1Cl)Nc1ccc(-n2cnnn2)cc1 +Nc1ccc2ccnc(C(=O)Nc3ccncc3)c2c1 +CS(=O)(=O)c1nc2ccccc2n1Cc1ccccc1 +Cc1nn(C)cc1-c1nnc(-c2ccc3c(c2)OCO3)o1 +Nc1ccc(Sc2nnnn2C2CC2)c(Cl)c1 +COc1ccc(NC(=O)NCCN2CCOCC2)c(Cl)c1 +O=C(NCC1CCCO1)c1c[nH]c2ccc(F)cc2c1=O +CCn1cc(C(=O)NCC2CCCO2)c(=O)c2cc(Cl)ccc21 +CC(C)(C)C(=O)N1CCC(N2CCNC2=O)CC1 +Cc1ccc(C(CNC(=O)c2cc(Cl)c[nH]2)N2CCOCC2)cc1 +Cc1ccc(CN(C)C(=O)Nc2cccnc2)cc1 +COc1cc(F)ccc1NC(=O)N1CCC(n2cccc2)CC1 +CCS(=O)(=O)c1ccccc1N1CCC(NC(=O)C2CC2)CC1 +CCNS(=O)(=O)c1ccc2c(c1)N(C(=O)CC)CC(C)(C)O2 +CC(C)(O)CCc1cccc(C(=O)N2CC3CC(O)C(O)CC3C2)c1 +Cc1ccc(-n2cnnn2)cc1NC(=O)c1ccc(C(F)(F)F)cc1 +CCC(CC)n1ncc(C(=O)NCc2ncn(C)n2)c1C +CC1CCCC1NC(=O)Nc1ccc(C(=O)NC2CC2)c(Cl)c1 +O=S(=O)(NCCC(O)c1ccccc1)c1ccc2c(c1)OCCO2 +Cc1nc(N(C)C)ncc1C(=O)N1CCCC(CCC(=O)N(C)C)C1 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1cccc(Cl)c1C +CN(C)c1ncc(NC(=O)c2c(F)cccc2F)cn1 +CCC(C)C(C)NC(=O)NC1CCN(S(C)(=O)=O)CC1 +CC(COc1ccccc1)C(=O)N=c1[nH]ncn1Cc1ccccc1 +CC(C)N(CCO)C(=O)c1cc(N)ccc1Cl +Cc1csc(-c2ccc(OCC(=O)NCc3cccs3)cc2)n1 +Cc1cccc(-c2nnc(SCc3nccn3C(F)F)n2C)c1 +CCn1c(SCCCC#N)nc2scc(-c3ccco3)c2c1=O +Cc1ccc(C)c(C(=O)NCc2ccccc2S(=O)(=O)N(C)C)c1 +COc1ccccc1C(C)(C)NC(=O)NC1CCC(O)CC1 +CN(C(=O)C1(C)CC1(Cl)Cl)c1ccc(Cl)cn1 +CNc1ccc(C2CN(C(=O)COC)CCO2)nc1 +CCc1cc2oc(=O)cc(CSc3nncn3C)c2cc1Cl +CC(c1ccco1)N(C)C(=O)Cc1cccc(F)c1F +COCCN1C(=O)c2ccccc2NC1c1cccc2ccccc12 +CCOC1CCN(c2ccc(C#N)cc2C(F)(F)F)CC1 +Cc1ccc(C)c(OC(=O)C2CCCN(C(=O)C3CC3)C2)c1C +CC(C)C1Oc2ccc(N)cc2N(CC(N)=O)C1=O +CCOC(=O)CN(C)C(=O)c1ccc(Br)c(N)c1 +Cc1cc2nc(C)c(S(C)(=O)=O)nc2cc1C +COC(=O)C(NC(=O)c1cnn(-c2ccccc2F)c1)C(C)C +COC(=O)CC(C)NC(=O)c1cnn(-c2ccc(F)cc2)c1C +C=CCOCC12CCCOC1CCN(C(=O)CCc1ccccc1)C2 +CC(NC(=O)c1cnc(C2CC2)[nH]c1=O)c1ccc2c(c1)CCCC2 +CCc1nc2c3cnn(-c4ccc(C)cc4C)c3ncn2n1 +CCCCNC(=O)C1CCCN(c2nc3ccccc3o2)C1 +CN(C)C(=O)CCc1cccc(NCC(=O)NC(C)(C)C)c1 +COc1ccc(CCNC(=O)Nc2ccc3c(c2)CC(=O)N3)cc1 +CCc1nc2sc(C)c(C)c2c(=O)n1CCO +Cc1ccc2c(CCNC(=O)c3occc3C)c[nH]c2c1 +CCc1nc2c(NC(=O)COc3ccccc3)cccn2n1 +COCc1cc(OC(=O)N(C)C)nc(-c2ccc(Cl)cc2)n1 +Cc1ccc(NC(=O)c2nc(NS(C)(=O)=O)sc2C)cc1 +Cc1cc(C)c(NC(=O)CSc2nnc(C)n2N)c(Cl)c1 +O=C(CNC(=O)Nc1ccc(F)c(F)c1)Nc1ccccc1 +CCOC(=O)c1cc(-c2ccc(O)c(OC)c2)nn1C +CC(NC(=O)NCc1cc(=O)[nH]c2ccccc12)c1ccc(C#N)cc1 +CC(C)c1nnc(NC(=O)CN(C)C(=O)c2ccccc2)s1 +N#CCSc1ccc(S(=O)(=O)N2CCOCC2)cn1 +Cc1ccc(-n2nnnc2CNC(=O)C2CC2)cc1C +O=C(NCc1ccccc1OCCO)c1ccc(-n2ccnn2)cc1 +CCC1CCCC(NC(=O)NC(C)C2CCCO2)C1 +COc1cc(N)ccc1NC(=O)CCCN1CCCC1=O +CC(=O)C(C)Oc1ccc2c(C(F)(F)F)cc(=O)oc2c1 +O=C(CCCOc1ccccc1F)Nc1ccnc2ccnn12 +CNC(=O)N(C)CCc1noc(COc2ccc(F)cc2)n1 +CCCOc1ccc(C(C)O)cc1Br +COc1ccnc(C(=O)Nc2ccccc2C(=O)C(C)C)c1 +O=C(CCc1ccc(O)c(Cl)c1)Nc1cc(-c2ccncc2)n[nH]1 +COc1cc(C#N)ccc1C1NCCc2ccc(O)cc21 +CN(Cc1cccc(C#N)c1)C(=O)c1cc(F)c(Cl)cc1Cl +CC(C)Cc1cc(CC2(NCc3ccccc3)COC2)no1 +Nc1cc(CCOc2ccc3c(c2)CCCC3)[nH]n1 +COCCN(CC(F)F)C(=O)NC1CC1c1ccc(F)cc1 +CCCc1nnsc1C(=O)N1CC(c2nc(C)no2)C1 +COc1ccnc(N2CCN(C(=O)Cc3ccc(F)cc3)CC2)n1 +COc1ccc2[nH]cc(C3=CCN(C(=O)c4cccn4C)CC3)c2c1 +COC(=O)N1CCC(NC(=O)c2cc3cc(C)ccc3nc2C)CC1 +CC(=O)c1cccc(NCC(=O)c2cccs2)c1 +CCc1noc(-c2ccc(CCNC(=O)N3CCOCC3)cc2)n1 +COc1ccccc1-c1nnc(SCC#CCO)o1 +CCCn1cc(NC(=O)C(Cc2ccccc2)n2cnnn2)c(C)n1 +CCOCC1CCCN(C(=O)c2cccc(NC(=O)C3CC3)c2)C1 +O=C(CNCCO)n1c(-c2ccccc2)cc2ccccc21 +Cc1ccc(-c2ncco2)cc1NC(=O)NCC(=O)OC(C)C +COc1cccc(C(=O)Nc2cccc(N3CCOC3=O)c2)c1 +CS(=O)(=O)NCC1OCC2CCN(c3ncccn3)CC21 +CCN(C(=O)CCCn1cncn1)C1CCCC1 +CCc1ccc(OCC(=O)Nc2ncccc2CO)cc1 +O=C(Nc1ccc(Br)cc1)c1ncc[nH]1 +CCc1nc(C2CCCN(C(=O)c3cnc(C)nc3CC)C2)no1 +Cc1ccc(C(C)NC(=O)Nc2cnn(C(C)C)c2)cc1F +COc1ccc(C(=O)CCN2CCOCC2)cc1-c1ccccc1 +CS(=O)(=O)N1CCC(CNC(=O)c2cccs2)CC1 +COC(=O)c1ccc(OS(=O)(=O)c2ccc(OC)cc2)cc1 +CNC(=O)Cn1cc(OC)c(=O)cc1CSc1ncccn1 +Cc1ccc(O)c(C(=O)N2CCc3ccccc3C2)c1 +CC(C)C(=O)Nc1ccc(CNC(=O)NCCc2ccco2)cc1 +Cc1nc(C2(NS(=O)(=O)c3c(C)noc3C)CCC2)no1 +CC(C)CC(=O)NCc1cnn(-c2ccc(F)cc2F)c1 +O=C(CN1CCN(Cc2n[nH]c(=O)[nH]2)CC1)N1CCOCC1 +Cc1ccccc1CNC(=O)CCn1ncc2c(C)cccc21 +CCC(CC)N(C)C(=O)CSc1ccc(C(C)=O)c(F)c1 +COCCOCC1NCCc2cc(Cl)cc(F)c21 +CCCCNC(=O)c1cc(F)ccc1Br +COc1ccc(CC(=O)OCC2CCCO2)cc1 +COc1ccc(CC(=O)NCc2cccc(N3CCCC3)c2)cc1 +Cc1ccc2c(NC(=O)c3cc(-c4ccccc4)nn3C)cccc2n1 +CCn1nnnc1NCc1ccc2c(c1)c1ccccc1n2CC +COc1cc(C(=O)OCC2CCCO2)ccc1OC(F)F +CNC(=O)C1(NC(=O)CCC(=O)OC)CCCCC1 +CC(C)(C)c1nnc(CNc2ccn(-c3ncccc3Cl)n2)o1 +COc1cccc2c1CCNC2Cc1ccc(O)cc1 +Cc1csc(NC(=O)c2ccc(C(N)=O)nc2)n1 +CN(Cc1cccs1)C(=O)Cn1ccnc1S(C)(=O)=O +COc1ccc2c(C(=O)N3CCCCC3)cc(=O)oc2c1 +CSc1ccccc1NC(=O)C1CC(=O)N(Cc2ccco2)C1 +COc1ccc(NC(=O)Cc2nnc(-c3ccsc3)o2)cc1OC +C#CCN1CCN(C2CCN(c3ccccc3F)C2=O)CC1 +CC(C)CN1C(=O)C2(CCCC2)N(C)c2ccc(N)cc21 +CCC(=O)Nc1ccc(OCC(=O)N2CCOC3CCCCC32)cc1 +Cc1ccc(C)c(C(O)CCCC(=O)NC(C)(C)C)c1 +COc1ccccc1OC(=O)c1[nH]nc(C)c1Br +CCc1ncc2c(n1)CN(c1ncnc3sccc13)CC2 +COc1ccc2c(c1)nc(C)n2Cc1ccccc1 +Cn1nc(CNC(=O)C2CCCCC2)c2ccccc2c1=O +CN(Cc1cnn(C)c1)S(=O)(=O)N1CCCCC1 +CCOc1cc(F)ccc1NC(=O)c1cnc2ccc(C)cn12 +O=C(Nc1nc2ccccc2s1)c1cc2ccccc2c(=O)[nH]1 +Cc1c(C(=O)NCc2cnn(Cc3ccccc3)c2)cnc2ccnn12 +CC(C)n1cc(C(=O)NCC(O)c2cccnc2)cn1 +CN(CC(=O)Nc1ccc(OCC#N)cc1)c1ccc(Cl)cn1 +CCC(C)(C)NC(=O)c1cc(C#CCO)ccc1F +Cc1noc(CN2CCCN(Cc3nc(C)no3)c3ccccc32)n1 +CCc1noc(CC)c1CC(=O)NCC1CCOC1C(C)C +Cc1cccn2cc(C(=O)N3CCN(c4ccc(F)cc4)CC3)nc12 +Cn1cc2c3c(cccc31)CN(C(=O)Cc1cccs1)CC2 +COc1cccc(OCC(=O)Nc2ccccc2Cl)c1 +Cc1n[nH]cc1CNc1cccc(N2CCCC2)c1 +COc1cccc(-c2nc(CN3CCc4cncnc4C3)cs2)c1 +CC(NCc1ccc(OC(F)F)c(Br)c1)C(N)=O +CC1CCN(C(=O)C2CCN(c3ncc(C#N)cc3Cl)CC2)CC1 +COC(=O)C(C)(C)NCc1cc(C#N)ccc1F +CCOC(=O)C(C)NC(=O)c1c(C)c(C)nn(C)c1=O +Cn1cnc(CNC(=O)NCC(C)(C)c2cccs2)n1 +CN(Cc1nnc2ccccn12)C(=O)Cc1ccc2ccccc2c1 +O=C(NC1CC1)c1ccsc1NC(=O)c1coc2ccccc12 +Cc1ccc(N2CC(C(=O)NCCO)CCC2=O)cc1C +CC(C(=O)N1CCCCC1c1nc(C(C)(C)C)cs1)n1cccn1 +Cn1ccnc1C(=O)c1ccc(Br)cc1 +C=CCNC(=O)Cn1nc(-c2ccccc2)c(OC)cc1=O +O=S(=O)(c1cccnc1)N(Cc1cccnc1)c1ccc(F)cc1 +COC(=O)CC(NC(=O)c1cnn(C)c1C)c1ccccc1Cl +Cc1ccc2ncc(C(=O)NCCC(F)(F)F)n2c1 +CC(=O)c1ccc(F)cc1NC(=O)c1cc2c([nH]c1=O)CCCC2 +COCCCCNC(=O)NCc1ccc(Br)cc1Cl +COCC(=O)N(C)CC(=O)Nc1cc(-c2ccccc2)ns1 +CS(=O)(=O)N1CCc2cc(NC(=O)Nc3ccc(F)cc3)ccc21 +Cc1ccc(NC(=O)N(C)c2c(C)noc2C)cc1S(C)(=O)=O +CC(=O)Oc1ccc2nc(COc3ccccc3)oc(=O)c2c1 +Nc1cc(NC(=O)c2ccc(F)c(F)c2)ccc1F +CCc1ccsc1C(=O)NCc1cccc(C#N)c1 +CC1(C)CCCN1C(=O)NC1CCCN(c2cccnc2)C1=O +CCn1cc(CNc2cccc(N3CCNC3=O)c2)cn1 +Cc1ccc(C(C)NC(=O)Cc2csc(C)n2)o1 +COc1ccc(C(=O)NC(C)C(=O)NCc2ccco2)nn1 +CCC1CN(Cc2c(OC)cc(OC)cc2OC)CC(C)O1 +O=C(CSc1nccn1Cc1ccccn1)c1c[nH]c2ccccc12 +Cc1ccc(N(CCC#N)C(=O)COC(=O)c2ccccn2)cc1 +COCC(NC(=O)c1cnn2c(-c3ccccc3)ccnc12)C(N)=O +COCCSc1nnc(Nc2ccc(OC)cc2)s1 +Cc1nnc(Sc2c(F)cc(N)cc2F)s1 +CCC(C)C(NC(=O)c1cc(-c2ccc(Cl)cc2)n[nH]1)C(N)=O +Fc1ccc(OCc2nnc3sc(-c4cccnc4)nn23)cc1 +CC(=O)Nc1ccc(OC(=O)c2csc(C)n2)cc1 +O=C(Nc1ccncc1)c1csc(-c2ncccn2)n1 +CC(=O)c1cccc(S(=O)(=O)Nc2c(C)nn(C)c2C)c1 +Cc1ccc(NC(=O)CCn2cnc3oc(C)c(C)c3c2=O)cc1 +C#CCOCC1CCCN(C(=O)NCc2ccccc2)C1 +COCC1CN(S(=O)(=O)Cc2ccccc2)Cc2c1cnn2C +Fc1cc2c(cc1C(F)(F)F)CCNC2c1ccccn1 +CCCc1ccc(C(=O)Nc2ccc3c(c2)CCC(=O)N3C)cc1 +CC(C)COc1ncc(CNC(=O)CN(C)C(N)=O)cc1Cl +Cc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)c(O)c1 +COCCNc1nc2cc3c(cc2s1)OCCO3 +CCc1cc(C(=O)Nc2cccc(C(=O)OC)c2)nc2ccnn12 +COc1ccccc1CCC(=O)Nc1cnc2c(c1)c(C)nn2C +COc1ccc(CN2CCN(C(=O)Cc3c(C)noc3C)CC2)cn1 +COc1ccc2c(CC(=O)NCC(C)O)coc2c1 +Cc1cccc(CNS(=O)(=O)N2CCOCC2)n1 +CC(=O)NC(C)C1NCCc2c(N)cc(F)cc21 +Cc1cc(=O)oc2c(C)c(OCC(=O)Nc3nccs3)ccc12 +COC1CCC(CC(=O)Nc2ccc(C(N)=O)nc2)CC1 +O=C(Cc1ccc2c(c1)OCCO2)OCc1nccs1 +CCn1c(SCc2c(C)noc2C)nnc1-c1ccco1 +COC(=O)C(Sc1nnc(Cn2cncn2)o1)C(C)C +Cc1nc(-c2cccnc2)sc1C(O)c1cccs1 +CCn1cnnc1CNC(=O)NCc1ccc(Cl)cc1Cl +COCC(=O)NC(Cn1cnc2ccccc21)c1ccc(F)cc1 +Cc1nn(C)c(C)c1C(C)NC(=O)Nc1cccc(-n2cccn2)c1 +CCC1(C)Nc2cc(OC)ccc2N(CCCC#N)C1=O +CN(Cc1ccco1)C(=O)CSc1ccccc1F +O=C(Nc1ccc(F)cc1F)N1CCc2c([nH]c3ccnn3c2=O)C1 +Cc1ccc2nc(C)c(C(=O)Nc3ccc4c(c3)COC4)cc2c1 +O=C(CCc1ccc(F)c(F)c1)Nc1cccnc1 +Cn1c(CCCNc2nc3ccccc3c(=O)[nH]2)nc2ccccc21 +O=C(C1CCCO1)N1CCN(c2nccc(C(F)(F)F)n2)CC1 +CCOC(=O)N1CCN(C(=O)CCc2ccccc2N)CC1 +CCC1Oc2c(Cl)cc(Br)cc2N(C)C1=O +O=C(Cc1cccs1)N1CCCC(c2cc(C(F)(F)F)[nH]n2)C1 +O=C(c1cc(C2CC2)[nH]n1)N1CCCC1c1noc(C2CC2)n1 +CS(=O)(=O)N1CCCC12CCCN(C(=O)c1ccnnc1)C2 +CC1(C)C2CCC1(C)C(NC(=O)Cc1n[nH]c(=O)c3ccccc13)C2 +CCC(CCO)NC(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1 +CN(c1cccnn1)C1CCN(C(=O)Cn2ccc3ccccc32)CC1 +COc1ccnc(N2CCN(C(=O)c3cnn(C)c3C)CC2)n1 +O=C(NCC1CCC1)Nc1ccc(F)c(Cl)c1 +COCCNC(=O)Cn1nc(-c2ccc(C)s2)cc(N)c1=O +CCC(=O)Nc1ccc(NC(=O)OC(C)(C)C)cc1 +CC(C)(CNC(=O)Cc1ccc[nH]1)NS(C)(=O)=O +Cc1ccc(OCC(=O)Nc2nc(C)c(C)s2)cc1C +CN(CCCC1CCCO1)c1ccnc(C(F)(F)F)n1 +CC(C)c1noc(CCCNC(=O)c2ccc(C(=O)N(C)C)cc2)n1 +COCCN(Cc1ccco1)C(=O)Nc1ccc(C(C)=O)cc1 +CN(C(=O)c1ccccc1)C(C#N)c1cccc(Cl)c1 +CCn1nc(C)c(C(=O)Nc2c(C(=O)OC)nn(C)c2C)c1C +N#Cc1ccc(NC2CCN(C(=O)C3CC3)CC2)nc1 +O=C(c1cc2ccccc2[nH]1)N1CCCCC1Cn1cccn1 +CC1CCCC(C)N1C(=O)CSc1nncn1C +O=C(CC1CC2CN(Cc3nccs3)CC2O1)N1CCOCC1 +COc1ccc2c(c1)C(O)(c1c(C)[nH]c3ccccc13)C(=O)N2 +O=C(CNCCC(F)(F)F)N1CCc2sccc2C1 +COc1ccc2c(CC(=O)N(C3CC3)C(C)C(C)C)cc(=O)oc2c1 +Nc1cccc(-c2noc(-c3ccccc3Cl)n2)c1 +Cc1nc(-c2ccncc2)sc1C(=O)N1CCC(C(N)=O)CC1 +O=C(Cc1ccc[nH]1)Nc1ccc(OC(F)F)cc1 +CC(C)Cc1nnc(NC(=O)Cn2ccc3ccccc32)s1 +Cc1cccc(C)c1OCc1nc2cc(N)cnc2o1 +NC(=O)CCn1c(SCc2ccccc2Cl)nnc1C1CC1 +Cc1nc(NCc2ccc(F)cc2)cc(C(=O)N2CCCC2)n1 +CCN(CC)S(=O)(=O)c1cccc(C(=O)NC2CC2)c1 +CNC(=O)c1ccc(Cl)c(NC(=O)COc2ccccc2C)c1 +O=C(Nc1ccc(F)cc1)c1ccc2c(c1)OCCCO2 +CC(C)C(C)NC(=O)NCC1(c2ccccc2F)CC1 +CC(C(=O)N1CCCC1)N1CCN(C(=O)CCC2CC2)CC1 +CCCS(=O)(=O)NC(C)c1ccc(OC(C)C)cc1 +O=C(NCCN1CCN(C(=O)c2ccccc2)CC1)c1ccsc1 +N#Cc1cc(NCc2c[nH]c3ccccc23)ccc1F +Cn1c(=O)c2c3c(sc2n2cnnc12)COC(C)(C)C3 +CN(Cc1ccccc1)C(=O)c1ccc2nc3ccccc3c(=O)n2c1 +C#CCN1CCN(C(=O)NC2CCN(C(=O)CC)C2)CC1 +CC(C)CS(=O)(=O)NCCC(O)c1ccco1 +COc1cccc(CNc2c(C#N)c(C(F)(F)F)nn2C)c1 +COC1CN(S(=O)(=O)C2CC2)C2CCCOC12 +CNC(=O)c1cccc(C2CN(c3nc(C)cc(C)n3)CCN2C)c1 +Cc1n[nH]c(-c2ccc(NC(=O)Cn3nnnc3C(C)C)cc2)n1 +CC(C)CNC(=O)NC(C)c1ccc(F)cc1F +Cc1csc(N(C(=O)c2cn3c(C)cccc3n2)c2ccccc2)n1 +COc1ccccc1CCC(=O)Nc1ccccc1OC +CN(Cc1ccc2c(c1)OCO2)C(=O)NCCN1CCCCCC1=O +COc1c[nH]c(C(=O)NCCC2=CCCCC2)cc1=O +CCCc1nnc(SC(C)C(=O)Nc2ccc(C)cc2)n1N +CC(C)(C)C(O)CCNC(=O)NCc1cccc2ccccc12 +Cc1ccc2cc(C(=O)Nc3nc(C(C)C)nn3C)c(C)nc2c1 +CCn1cc(C(=O)NCCC(=O)Nc2ccc(C)cn2)cn1 +COC1CCC(CC(=O)Nc2cc(C)n[nH]2)CC1 +COc1ccc(OC)c(Nc2ncnc3c2nnn3C)c1 +c1csc(-c2nnc(CSc3nnc(C4CCCCC4)o3)o2)c1 +O=S(=O)(c1ccccc1OC(F)(F)F)N1CCNCC1 +O=C(Nc1ccccc1)C1(S(=O)(=O)c2ccccc2)CC1 +Cc1ccc(-c2nnn(CC(=O)N3CCOC(C)(C)C3)n2)cc1 +O=C(CSc1nnc(-c2ccco2)o1)NCC1CCCCC1 +Cc1nc(CCNC(=O)C2CC2c2ccccc2Cl)cs1 +CCOC(=O)Nc1ccc(NC(=O)N2CCOC(C)C2)cc1 +Cc1nccn1-c1ccc(NC(=O)NCCCN2CCOCC2)cc1 +CC(C)Nc1ncccc1C(=O)N1CCN(CC(=O)C2CC2)CC1 +CN(C)c1ncccc1N(C)C(=O)Cc1c[nH]c2ccccc12 +CC(C)N(CCCO)C(=O)Cc1cccc(O)c1 +O=c1[nH]c(CNc2ccc(Cl)cc2)nn1Cc1ccc(F)cc1 +CCOc1ccc2ccccc2c1C(=O)NCc1cc(C2CC2)n(C)n1 +O=C(NCCC(O)c1ccco1)C1c2ccccc2Oc2ccccc21 +O=C1CSc2sc3c(=O)n(Cc4ccccc4)cnc3c2N1 +CCOC(=O)C(C)Sc1nc(CC)cc(=O)[nH]1 +CC1(C(=O)NCC2CCCC2)CC1(Cl)Cl +COC(=O)c1ccc(S(=O)(=O)N2CCOCC2)c(Cl)c1 +COC(=O)c1cc(NC(=O)COc2ccc(OC)cc2)ccc1Cl +CC(CN1CCOCC1)NCc1cc(F)ccc1F +O=C(NCc1ccc2[nH]c(=O)[nH]c2c1)c1ccc2ncccc2c1 +Cc1csc(=O)n1CCSc1nnnn1C +CS(=O)(=O)c1ccsc1NC(=O)c1ncoc1-c1ccco1 +CCCc1nnsc1C(=O)N1CC(c2nc3ccccc3[nH]2)C1 +CC(C)c1ccc(C#N)c(=O)n1CCCOc1ccccc1 +COCc1ccccc1NC(=O)NCc1cc[nH]n1 +CCN(Cc1cccc(F)c1)C(=O)Nc1cc(C(N)=O)ccc1C +Cc1cc(C)c(C(C)C(C#N)N2CCOCC2)c(C)c1 +Cc1ccc(C)c(-c2cc(C(C)(C)O)c(=O)[nH]n2)c1 +O=C(CC1CC1)NC1CN(Cc2nccs2)C2COCC12 +CC(C)C(=O)N1CCCC(COc2cccc(C(=O)NC3CC3)c2)C1 +O=C1COc2ccc(C(=O)C3CCCCN3)cc2N1 +NC(=O)C1CCN(S(=O)(=O)c2ccccc2Cl)CC1 +O=C1OCCN1CCC(=O)N1CCCCC1Cc1ccccc1 +O=S(=O)(c1ccc2c(c1)NCCO2)N1CCCCC1 +Cc1ccc2nc(C(=O)NCc3nc(C)c4c(n3)CCCC4)cn2c1 +Cc1nn(-c2ccc(Cl)cc2)c(C)c1CC(=O)NCCCC(N)=O +Cc1ccc(Cn2nccc2NC(=O)c2ccnc(-n3cncn3)c2)o1 +COc1ccc2c(c1)OCC(CNC(=O)c1n[nH]c3c1CCC3)C2 +N#CC1CN(Cc2cnc(-c3ccsc3)s2)CCO1 +Cc1cc(C)c(N=C(O)CN2CCN(C(=O)C3CC3)CC2)c(C)c1 +O=c1[nH]c(CN2CCCC2c2cccs2)nc2ccccc12 +O=C(OCC1CCCO1)c1ccc(SC(F)F)cc1 +O=C(Oc1ccc2cn[nH]c2c1)c1ccc2c(c1)OCO2 +O=C(NCCN1CCOCC1)C1CCN(c2ccc(F)cc2)C1=O +COc1ccc(O)c(C(=O)N2CCC(OCC(C)C)CC2)c1 +CCC(C)NC(=O)C1CCN(c2ccc(F)cc2)C1=O +CCCOc1ccc(CNc2ncnc3[nH]cnc23)cc1OC +NC(C(=O)Nc1ccc2c(c1)N(C(=O)C1CC1)CCC2)c1ccccc1 +CCN(Cc1nc(-c2cccs2)no1)C(=O)c1ccc(OC)cc1 +CCCCCNC(=O)CN1CCN(c2ccccc2)C1=O +C=CCNC(=O)c1ccc(NC(=O)C(C)Sc2nncn2C)cc1 +COC(=O)c1cc(CNC(=O)c2ccco2)oc1C +O=C(NCc1ccccc1)c1cnn(-c2ccccc2)c1-n1cccc1 +Nc1ccc2oc(CC(=O)NC3CCCCC3)nc2c1 +COC(=O)c1c(NC(=O)c2ccc(-c3ccccc3)cc2)c(C)nn1C +Cc1ccc(Cc2nnc(NC(=O)NC(C)C)o2)c(C)c1 +Cc1cccc(NC(=O)NC(c2noc(C)n2)c2ccccc2F)c1 +C#Cc1cccc(NC(=O)c2cccnc2N(C)C)c1 +CC(=O)NCCn1c(SCC#N)nc2ccccc2c1=O +CCOC(=O)C1CCCN(C(=O)NCC(C)(C)c2ccncc2)C1 +Cc1[nH]ncc1S(=O)(=O)Nc1cccc(Cl)c1C +Cc1c(Cl)c(C(=O)Nc2nc3ccccc3n2C)nn1C +Cc1ccccc1S(=O)(=O)Nc1ccc(N)c(Cl)c1 +CC(OC(=O)C1COc2ccccc2O1)C(=O)Nc1ccccc1 +Cc1nc(-c2ccsc2)ccc1C(=O)NCCS(N)(=O)=O +Cc1ncc(CNc2cccc(-c3nnnn3C)c2)s1 +Cc1noc(C2CCCN2C(=O)NC(C)(C)C)n1 +COCCNC(=O)c1csc(-c2ccncc2)n1 +CNC(=O)c1ccc(Cn2nnc(-c3ccccc3C)n2)cc1 +O=C(NCCC1CNc2ccccc21)c1ccccc1F +COc1ccc(S(=O)(=O)N(C)c2cccc(O)c2)cc1 +O=C1C(n2cnc3ncccc3c2=O)CCN1CC(F)(F)F +C=CCNc1ncnc(Nc2ccc(C)cn2)c1N +CCC1CN(Cc2cc(=O)n3c(C)csc3n2)CCO1 +O=C(CN1C(=O)CCc2ccccc21)Nc1ccc(-c2cc[nH]n2)cc1 +O=C(c1cccs1)N(Cc1cccnc1)Cc1ccco1 +NC(=O)NCc1ccc(C(=O)Nc2ccc(Cl)cc2)cc1 +Cc1ccc(C(=O)COc2ccc(N)cc2F)cc1C +Cc1nc2nc(N)nn2c(C)c1CCc1nc(Cc2ccccc2)no1 +CC(C)(C)OC(=O)N1CCC(C(=O)N2CCCC2c2ccc[nH]2)CC1 +Cc1cc(C(=O)N2CC3CC4CC(C3)CC2C4)on1 +CC(=O)Nc1cccc(-n2nnnc2SCc2nc(C)no2)c1 +N#Cc1ccc(NCC2CCCO2)c(C(F)(F)F)c1 +Cc1nnsc1C(=O)N(Cc1ccccc1)C(C)C +COC(=O)c1c(C)ccc(F)c1NC(=O)C1CC(=O)N(C2CC2)C1 +O=C(C1CCCCC1)N1CCN(CCn2cccn2)CC1 +O=C(c1ccc2[nH]cnc2c1)N(CCc1ccccc1)C1CCOC1 +CCOc1ccc(OC)cc1NC(=O)c1ccc(=O)n(C)c1 +Cc1ccncc1NC(=O)NCCc1ccccc1F +O=c1c2cnc3nc(C(F)(F)F)nn3c2ccn1-c1ccccc1F +Cc1cc(C)n(CC(=O)OCC(=O)c2ccc[nH]2)n1 +CCC(NC(=O)C1C2CCCCC21)c1cnn(CC)c1 +Cc1ccc(N2CCOCC3(CCCN(C(=O)NC4CC4)C3)C2)nn1 +CC(c1ccncc1)N(C)c1cnc2ccccc2n1 +O=C(CCc1nc2ccccc2s1)NCCCO +CCCNC(=O)c1cccc(CNC(=O)N2CCC(C(N)=O)CC2)c1 +CCS(=O)(=O)N1CCC(NC(=O)C2CCCCC2)CC1 +CC(=O)Nc1nc(CNC(C2CCCC2)C(F)(F)F)cs1 +CSc1c(C#N)c(N)c(C#N)c(N)c1NC(C)=O +O=C(C1CCC1)N1CCCC(OCc2cc(F)ccc2F)C1 +COc1ccc(NC(=O)N2CCCC(C)C2CO)cc1OC(F)F +CC(NC(=O)CSc1nccn1C)c1ccc(F)cc1 +NC(=O)C1CCN(C(=O)COc2ccc3ccccc3c2)CC1 +CCCS(=O)(=O)NCC1CCN(C(=O)c2ccccc2)CC1 +O=C(NCc1ccccc1Cl)C1CCN(c2ccccc2)C1=O +CCCS(=O)(=O)N1Cc2ccccc2N(C)CC1CC +CCN(Cc1nc(C)c(C(C)=O)s1)C(=O)OC(C)(C)C +Cc1ccc(F)cc1NC1COc2cc(O)ccc21 +O=C(Nc1n[nH]c(C2CCC2)n1)c1cc2ccccn2c1 +O=C(OC(C(=O)N1CCCCC1)c1ccccc1)c1cccnc1 +CC(Sc1nnnn1C1CCCC1)C(=O)N1CCCCCC1 +CC1(C)CN(C(=O)Nc2ccccc2-n2cccn2)CCO1 +O=C(CNC(=O)c1cccc(F)c1)c1ccc(F)c(F)c1 +CC(C)CN(CC(N)=O)C(=O)CC1CC2CCC1C2 +CCCc1cnc(C)nc1NCc1ccc(S(N)(=O)=O)cc1 +Cc1noc(C)c1C(=O)OC(C)C(=O)NCc1cccs1 +O=C(Cc1ccccc1F)NCCNS(=O)(=O)c1ccccc1 +NC(=O)C(NCC1(c2ccccc2F)CC1)c1ccc(F)cc1 +CCS(=O)(=O)NCCc1ccc2c(c1)OCCO2 +COCCn1nc(C(=O)N(C)Cc2ccc(C)o2)ccc1=O +Cc1ccc(C(=O)NCCN(C(=O)c2ccc(C)n2C)C2CC2)n1C +CCC(=O)N1CCCC(C(=O)N2CCN(C(=O)c3ccc[nH]3)CC2)C1 +CS(=O)(=O)Oc1nncc(-c2ccccc2)n1 +COC(=O)C(C)n1c(CCO)nc2cc(N)ccc21 +O=C(CCCc1nnc2ccccn12)N1CCOCC1 +C=CCNC(=O)CCC(=O)c1cc(Br)ccc1OC +COc1cc(C)ccc1OCC(=O)NCC(C)(C)N1CCOCC1 +CCC(C)NC(=O)C(NC(=O)c1cccc(C)c1)C(C)C +CCOC1CCCN(C(=O)Nc2cc(NC(C)=O)ccc2Cl)C1 +Cc1ccc(-c2nc(C(=O)Nc3ccc(N(C)C)nc3)cs2)o1 +COc1ccc(CNc2ccc3ncccc3c2)cc1O +O=C(NCC1CC1)c1ccc2c(c1)CC(=O)N2Cc1ccccc1 +CCOc1ccc(C(=O)N2CCc3ccccc3C2)cc1 +N#Cc1ccc(C(=O)Nc2ccc(NCC3CCCO3)c(F)c2)cc1 +Cn1c(SCC(=O)N2CCC(C(N)=O)CC2)nc2ccccc21 +N#Cc1ccccc1CSc1nnc(-c2ccc(F)cc2)n1N +CN(Cc1ccc(O)cc1)C(=O)c1cc(-c2ccccc2)no1 +COc1ccc(CNC(=O)c2cnc(-c3ccccc3)nc2)c(OC)c1 +FC(F)(F)c1cc(Br)cc2cn[nH]c12 +CCN(CC(C)C#N)C(=O)Nc1ccc2c(c1)OCO2 +Cc1nc(C)c(C(C)NC(=O)Cc2coc3c(C)c(C)ccc23)s1 +CC(CN1CCOCC1)N(Cc1ccccc1)Cc1nccn1C +O=C(NCCNc1nnnn1-c1ccccc1)c1ccccn1 +Cc1ccc2c(c1F)C(c1ccc(N)cc1)NCC2 +Cc1cc(CN(C)C(=O)NC2CCCC(C)C2C)no1 +Cc1cc(CNc2nc(C3CCCC3)nc3c2cnn3C)cnc1C +CCOC(=O)c1nnc(C=Cc2cccc(Br)c2)s1 +Cc1ccccc1OCCCN1CCCCS1(=O)=O +CCc1ccc(N(C(C)C(N)=O)S(C)(=O)=O)cc1 +NC(=O)NC(Cc1ccccc1)C(=O)N1CCc2ccccc2C1 +CCOC(=O)C(C)CNC(=O)Nc1ccccc1C(F)(F)F +COc1cccc(C(N)=O)c1OCC(=O)NCc1ccccc1C +O=C(CN1c2cccc3cccc(c23)S1(=O)=O)N1CCC1 +COc1cccc(CC2CN(C(=O)Cc3ccn(C)c3)CCO2)c1 +CCN1C(Cc2cccn2C)C(O)c2ccccc2S1(=O)=O +Cc1ccc(S(=O)(=O)Oc2c(C)nn(C)c2C)cc1N(C)C +CC(NC(=O)Cn1[nH]c(=O)c2ccccc2c1=O)c1ccccn1 +O=C(Cc1cccc2cccnc12)NC1CCN(c2ccccc2)C1=O +COCCCNC(=O)Nc1cccn2nc(C3CC3)nc12 +CCn1c(=O)cc(OCC(=O)Nc2cc(C)ccn2)c2ccccc21 +COCCn1c(C(C)NC(=O)c2cccc(C)c2)nc2ccccc21 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1ccc(Cl)cc1F +O=C(Nc1ccc2c(c1)OCO2)c1ccc(-n2cccn2)cc1 +CCCC(=O)N1CCc2nc(NC(C)=O)sc2C1 +O=C(Cn1cnnn1)NCc1ccc(CN2CCCC2=O)cc1 +CC(C)Nc1ncnc(Sc2cccc3cccnc23)c1N +N#Cc1ccc(Cl)cc1NC(=O)CN1CCOCC1C1CC1 +CC(C)CC(NS(=O)(=O)N(C)C1CCOCC1)c1cccs1 +CC1CC1c1ccc(CN(C)C(=O)CCNC(=O)C2CCCC2)o1 +Cc1cc(C(=O)NC(C)c2cccc(F)c2)c(C)s1 +O=S(=O)(CCOc1ccccc1)N1CCc2ccccc21 +CN(C(=O)c1ccncc1Cl)c1ccc(-c2ccccc2)nn1 +COc1cc(C(=O)Nc2nc[nH]n2)cc(OC)c1OC +COc1ccccc1OCC#CCNC(=O)c1c(F)cccc1F +COc1ccccc1C(=O)NCC(=O)Nc1ccccc1 +Cn1cc(NC(=O)NCCc2ccc(Cl)cc2)cn1 +CS(=O)(=O)c1ccc(C(=O)Nc2nnc(C3CC3)s2)cc1 +Cc1nc(C(N)c2ccccc2C(F)(F)F)no1 +CC1CN(CC(O)c2ccccc2Cl)CC(C)O1 +Cc1cnc(NC(=O)NCc2ccccc2C)s1 +CCC(NC(=O)c1ccc(-n2ccnn2)cc1)c1c(C)nn(C)c1C +O=C1CCC2(CCOC2)CN1Cc1c(F)cccc1Cl +CCn1nc2c(cc1=O)CN(C1CC(C)OC1=O)CC2 +COc1cccc(CNC(=O)C2CC(=O)N(C3CCCCC3)C2)c1 +COC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2ccc(F)cc2N)c1C +Cc1ccc(NC(=O)c2ccc(N3CCCCCC3)nc2)nc1 +O=S(=O)(c1ccc2ccccc2c1)N1CCN=C1c1ccccc1 +CCOC(=O)C1CCC(NC(=O)Nc2c(C)noc2CC)C1 +CCCC(=O)N1CCCC(C(=O)N2CC(C)c3ccccc32)C1 +O=C(Cc1ccccc1O)NCC1CN(Cc2ccccc2)CCO1 +CNC(=O)COc1cccn2c(-c3ccc(N)cc3)nnc12 +OCc1ccc(Cl)c(NCc2nc(Cc3ccccc3)no2)c1 +CC(=O)NCC(c1c(F)cccc1Cl)N1CCOC(C)C1 +CC(=O)Nc1ccc(Sc2ccccc2N)cc1 +Cc1csc(Nc2ccc3c(c2)OCCCO3)n1 +COC(=O)CCC(=O)Nc1c(C(C)C)cccc1C(C)C +COC(=O)c1ccc(Oc2ccc(-c3csc(C)n3)cc2F)nn1 +Cc1sc(NC(=O)C2Oc3ccccc3OC2C)c(C#N)c1C +Cc1nnsc1C(=O)N1CCN(C2CC2)CC1Cc1ccccc1 +CC(C)c1cccc(OCCN2C(=O)CCS2(=O)=O)c1 +CCCC(=O)Nc1cccc(NC(=O)c2ccco2)c1 +COc1cc(NC(=O)CSc2nc(N)cc(N)n2)cc(OC)c1 +COc1ccc(C(O)C(=O)Nc2cccc(C(C)=O)c2)cc1 +N#Cc1ccc(OC2CCC(NC(=O)N3CCCC3CO)CC2)nc1 +COc1ccc(CSc2nnc(C)s2)cc1 +CCNC(=O)c1ccc(NC(=O)c2ccsc2)c(C)c1 +O=S(=O)(c1ccc2ccccc2c1)N(Cc1ccco1)C1CC1 +CC(C)C(=O)Nc1cnc(N2CCOCC2)nc1N(C)C +CCC1CCCC(NC(=O)C(CC(C)C)NC(N)=O)C1 +N#CCCCn1nc(C#N)cc1-c1ccc(Cl)cc1 +COCCN(Cc1ccco1)C(=O)c1ccnc(-n2cncn2)c1 +Cc1ccc2ncc(C(=O)NC3(C)CCOC3)n2c1 +Cc1ccc(C(C)NC(=O)c2cn(CC(=O)N(C)C)nn2)cc1 +Cc1cccc(C(C)C)c1NC(=O)c1cccc(NC(N)=O)c1 +COc1ccc(OC)c(C(=O)CC2OC(=O)c3ccccc32)c1 +COc1ccc(NC(=O)CNc2c(C)cc(C)cc2C)c(OC)c1 +CCC(CC)C(=O)Nc1cccc(S(=O)(=O)NC)c1 +O=C(NCC1CCCO1)c1cccc2ncccc12 +CCc1noc(CC)c1CNC(=O)c1ccnc(SC)c1 +O=C(C1CC=CCC1)N1CC(S(=O)(=O)c2ccc(F)cc2)C1 +Cc1ccc(-n2cnnc2S(=O)(=O)Cc2cc(C)on2)c(C)c1 +COCC(=O)Nc1ncc(Cc2ccccc2)s1 +CC1CCCN(S(=O)(=O)c2sccc2Br)C1 +Cc1nc(-c2ccccn2)sc1C(=O)N(CC1CCOC1)C1CC1 +O=C(Nc1ccc(OC(F)F)cc1)NC1(CO)CCCC1 +CCN(Cc1cnn(C)c1)C(=O)NCc1ccccc1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCC(=O)N1CCCCC1)O2 +Cc1c(F)cc(C(=O)NCC(F)(F)F)cc1NC(=O)C(C)(C)C +Cn1cc(C2CN(S(=O)(=O)CC3(C#N)CC3)CCO2)cn1 +Cc1cccc(NC(=O)c2cc(C)nc3c2c(=O)[nH]n3C)c1 +c1ccc(-n2cc(CN3CC(Oc4cccnc4)C3)nn2)cc1 +Cc1cccc(NCCC(=O)c2ccc3c(c2)OCCCO3)c1 +Cc1cc(F)ccc1NC(=O)NCc1cnn(C)c1 +CC(C1CCN(C(=O)Cn2ccnc2)CC1)N1CCOCC1 +Cc1ccn(-c2ccc(N(CCO)Cc3cccnc3)nn2)n1 +COc1ccccc1-c1nccn1Cc1ccc(C#N)cc1 +CCCc1nc2ccccc2n1C(C)C(=O)NCCc1ncnn1C +CCn1cc(CC(=O)Nc2ccnn2C(C)C2CC2)c2ccccc21 +O=C(CN1C(=O)CSc2ccccc21)N1CCCC1 +CCS(=O)(=O)Nc1ccc(C#CCCO)cc1 +COc1cc(S(=O)(=O)Oc2ccccc2F)ccc1NC(C)=O +CC(C)Nc1cccc(CNC(=O)CCc2cnn(C)c2)c1 +CCOc1ccc(C(C)NC(=O)c2ccoc2C)cc1OCC +CN(c1ccc(F)c(Cl)c1)S(=O)(=O)CCCC#N +C=CC(C)NC(=O)Nc1ccc(Oc2cccnc2)nc1 +COC(=O)C1=C(C)NC(=O)NC1c1cc(OC)cc(OC)c1 +CC1CCC(NC(=O)c2ccc3nc4ccccc4c(=O)n3c2)CC1 +COc1ccc(CC(C)C(=O)Nc2nc(SC)ns2)cc1 +O=C(NC(CCO)c1ccccc1)c1ncn(-c2ccccc2)n1 +CCCOc1ccc(-c2ncc(C#N)c(N)n2)cc1 +Cn1cnc(CNC(=O)Nc2ccc3[nH]ccc3c2)n1 +CS(=O)(=O)NC1CCN(C(=O)C2COc3ccc(F)cc3C2)C1 +Cc1ccc(-n2c(C)nc3c(cnn3-c3ccc(C)cc3)c2=O)cc1 +C=CCNC(=O)CCc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CCc1cc(=O)n2c(n1)SCC2CC(=O)Nc1nc(C)cs1 +CC(=O)c1cc(CN2CCN(c3ncc[nH]c3=O)CC2)cs1 +CC(=O)NCCNC(=O)Nc1cccc(N2CCCCC2)c1 +O=C(Cn1nnc(CO)c1C1CCCO1)Nc1ccccn1 +COc1ncccc1-c1cc(=O)[nH]c(NCc2ccc(Cl)cc2)n1 +CCc1nc(N2CCOCC2)ncc1C(=O)N1CCC(CO)C1 +CC(Cn1cccn1)OC(=O)c1ccc2ccccc2n1 +CN(C)C(=O)C(Cc1ccccc1)Nc1ncccc1C#N +CCC(NC(=O)c1cccc(-c2ccoc2)c1)C(=O)N1CCOCC1 +Cc1cccc(NC(=O)COC(=O)CCc2c(C)nn(C)c2C)c1 +O=C(NCC1(O)CCOCC1)c1ccc(C(F)(F)F)cc1 +NC(=O)COc1ccccc1C(=O)NCc1ccccn1 +CC(=O)c1csc(C(=O)N(c2cccc(F)c2)C2CCOCC2)c1 +O=C(Cn1cnc2sccc2c1=O)N1CCCCC1 +COc1ccc(OC(F)F)c(CN2CCOC(C)(C)C2)c1 +COc1cc2c(cc1OC)C1C(CC(C)C)C(=O)CCN1CC2 +Cc1cc(NC(=O)CCc2ccc(C#N)cc2)ccn1 +O=C(Cc1c(F)cccc1Cl)NCCc1cccc(O)c1 +CC(=O)c1cccc(NC(=O)Cn2nc(C)ccc2=O)c1 +CC1CCN(S(=O)(=O)NCc2cc(-c3ccccc3)on2)CC1 +CCOc1ncccc1CNC(=O)c1cc(S(N)(=O)=O)ccc1C +COc1cc2oc(-c3ccc(O)cc3)cc(=O)c2c(OC)c1OC +Cc1nn(CC(=O)Nc2ccc3c(c2)COC3)c(=O)c2ccccc12 +CCn1cc(CNc2nncc(-c3ccccc3F)n2)cn1 +COc1ccc(-n2c(C)nc3cc(C(=O)NC4CCCC4)ccc32)cc1 +CC(C)CCCC(C)NC(=O)c1c[nH]c2ccccc2c1=O +CCCC(=O)NCC(=O)NCc1cccc2ccccc12 +Cc1ccc(-n2c(SCc3ccccn3)nc3c(=O)[nH]cnc32)cc1 +CCOCc1ccc(C(=O)Nc2ccc(C(C)=O)cc2)o1 +CCc1nnc(Sc2nn3cc(C)nc3s2)n1C +Cc1cc(NCC2Cc3ccccc3O2)nc(-c2ccncc2)n1 +CC(=O)N(c1nc(CSc2nncn2C(C)C)cs1)C1CC1 +c1ccc(-n2cnc(CSc3nncn3Cc3ccco3)n2)cc1 +COC(=O)c1csc(CN(C(=O)c2cccc(F)c2)C2CC2)n1 +Cc1nc(CNC(=O)Nc2c[nH]c(=O)c(C)c2)c(C)s1 +COCC(=O)N1CCC(NC(=O)c2cccnc2)CC1 +COc1ccc(OC)c(-c2cc(C#N)c(=O)n(C)n2)c1 +COc1ccccc1NC(=O)CSc1nc2cccnc2n1C +O=C1OCC(c2ccccc2)=C1Cc1ccccc1 +CC(=O)Nc1cc(NC(=O)N(C)Cc2ccccc2Cl)ccc1F +Fc1ccc(OCc2noc(CN3CCc4cncnc4C3)n2)cc1 +CC(C)CCn1cc(C(N)=O)c(=O)c2c(N)cccc21 +CC(=O)Nc1ccc(F)c(C(=O)Nc2ncccc2C)c1 +CN(CC(N)=O)C(=O)C1CC1c1ccccc1Cl +CCCN(CCC)C(=O)c1cc(-c2cccc(OC)c2)n[nH]1 +Cn1cccc1CN1CCN(CCNC(=O)c2ccccc2F)CC1 +CN(Cc1cnn(-c2ccc(F)cc2)c1)C(=O)COCC1CCCO1 +O=C(NCCNC(=O)C1CC1)c1cc(C2CC2)nn1-c1ccccc1 +Oc1cc(O)cc(C2NCCc3ccc(Cl)cc32)c1 +Cc1ccc(C(C)NC(=O)CN2CCN(C(=O)CO)CC2)cc1C +Cc1nn(C)cc1S(=O)(=O)Nc1ccccc1-c1ccccc1 +NC(=O)c1ccc(NCc2ccc(O)c(Cl)c2)cc1 +CS(=O)(=O)NC1CCOC2(CCN(C(=O)C3CCOCC3)C2)C1 +CCc1nc(CN2CCCC(c3nnc4ccccn34)C2)no1 +Cc1ccc(-c2nc(CNC(=O)c3ccnn3C(C)C)no2)cc1 +CC(NC(=O)N1CCN(C(=O)CC(F)(F)F)CC1)c1ccccn1 +Cc1ccc(C(=O)NCCc2c[nH]c3ccc(F)cc23)cc1 +Cc1ccc2ncc(C(=O)Nc3ccccc3N(C)C)n2c1 +CCOCCn1c(=O)[nH]c2cc(C(=O)NCc3n[nH]c(C)n3)ccc21 +Cc1n[nH]c2ncc(C(=O)NCCC3=CCCCC3)cc12 +O=C(Nc1ccccc1)NC1CCN(C(=O)c2cnc3cc[nH]c3c2)C1 +O=C(c1ccc(-n2cccc2)cc1)N1CC(c2nc3ccccc3[nH]2)C1 +CC(NC(=O)COc1ccccc1O)c1cccc(Cl)c1 +CCCC1CN(Cc2cccc(OC)c2OC)CCO1 +Cc1nn(CCO)c(C)c1CN(C)C1c2ccccc2-c2ccccc21 +CC(C)NC(=O)c1ccc(Cl)cc1NC(=O)c1ccc[nH]1 +FC(F)(F)Oc1ccc(CNCc2ccnc(-n3cccn3)c2)cc1 +CC(=O)NCC(=O)Nc1ccc(C)cc1OCC(F)(F)F +CCC(C)NC(=O)Cn1nc(-c2ccc(Cl)cc2)ccc1=O +Cc1cc(NC(=O)NCc2cccc(C#N)c2)n(C)n1 +CCn1c(C)cc(C(=O)Nc2ccc(-n3cncn3)c(F)c2)c1C +COc1ncc(Cl)c(NCc2ccc(-n3cncn3)cc2)n1 +CCCCCSc1nnc(C)n1-c1cccc(NC(C)=O)c1 +Cc1ccn2c(C(=O)NCCNc3ccccc3)cnc2c1 +CCC(=O)N1CCN(CC(=O)N2CCCC2)CC1 +Cc1c(NC(=O)Nc2ccncc2)cccc1NC(=O)c1ccccc1 +CCc1cc(CC(C#N)C(=O)N(CC)CC)ccc1OC +O=C(NCCNC(=O)N1CCc2ccccc2C1)c1cccnc1 +CSc1nc2ncc(C#N)c(C(F)(F)F)n2n1 +Cc1cc(NCc2cnn(-c3ccc(F)cc3)c2)n2nccc2n1 +O=c1ccc(C(F)(F)F)cn1CCCOc1ccccc1 +CCOC(=O)c1cccc2nc(CC#N)n(CCO)c12 +CC(NC(=O)c1ccoc1)C(=O)NC1CCCC1(C)CO +Cc1cc(C)c(C(=O)N(Cc2ccncc2)CC2CCC(=O)N2)o1 +COCCN1CC(c2nc(C(C)C)no2)CCC1=O +CC(=O)NC(C(=O)N(C)C(C)c1ccc(-n2cncn2)cc1)C(C)C +CCCOc1ccccc1-n1nnnc1-c1ccc(N)cc1 +COC(=O)c1nccc2cc3c(cc12)OCCCO3 +CC(=O)c1nnn(CC(=O)Nc2ccc(C)c(Cl)c2)c1C +CNC(=O)C1CCCCN1C(=O)c1cccc(S(=O)(=O)NC)c1 +CCOCC1CCCN(C(=O)CSc2ccc(F)c(F)c2)C1 +CC(C)CNC(=O)C(C#N)c1nccn1CC(F)(F)F +CCCc1ccc(C(O)CNC(=O)c2cccnc2)cc1 +CC(=O)c1ccc(S(=O)(=O)Cc2ccc(C#N)cc2)cc1 +CCOc1cc(NC(=O)c2ccco2)ccc1OC +O=C(Nc1ccccc1)Nc1ccc(C(=O)N2CCC(O)CC2)s1 +CCN(C(=O)NCc1nncn1CC)C1CCCCC1 +Cn1ccc(C(=O)Nc2ccc3c(c2)OCCO3)n1 +CCOc1ccc2nc(N3CCC(C(=O)NC4CC4)CC3)sc2c1 +CCCc1nc2cc(Br)cnc2n1CC#N +CNC(=O)c1cccc(OCc2nc(CC(C)C)no2)c1 +COC(=O)c1cnc(N2CCCCC2C)c2ccccc12 +CCS(=O)(=O)NCc1ccc(-n2cncn2)cc1 +CCOCc1ccccc1CNC(=O)N1CCN(C(=O)N(C)C)CC1 +CN(C)S(=O)(=O)N1CCC(NC(=O)c2cccs2)CC1 +CC(C)Cc1cc(C(=O)Oc2ccc(N3CCOC3=O)cc2)[nH]n1 +Cc1ccoc1C(=O)Nc1cccnc1-n1cccn1 +CCNC(=O)N1CCN(CCOc2cccc(C)c2)CC1 +Cc1ncc(CNC(=O)c2[nH]nc3c2CCCC3)s1 +CCOc1ncccc1C(=O)OC(C)C(=O)NC1(C#N)CCCCC1 +COC(=O)CC(C)Nc1ccccc1C(F)(F)F +O=C(Cn1ccc(=O)[nH]c1=O)Nc1ccc2c(c1)Cc1ccccc1-2 +CCCNC(=O)NCc1cccnc1-n1cccn1 +O=C(Cc1cccc(NC(=O)c2cnn3c2OCCC3)c1)NC1CC1 +O=C(CN1CCOCC1C1CC1)Nc1ccccc1C(=O)NC1CC1 +Nc1cnc(-c2ccc3c(c2)NC(=O)CS3)nn1 +Cn1c(C(=O)Nc2nc3c(s2)CCC3)cc2cc(F)ccc21 +Cc1ncc(CNC(=O)N2CCN(c3ccccc3O)CC2)s1 +Cn1cc(CNc2oc(-c3ccccc3)nc2C#N)cn1 +Cc1cccc(NC(=O)CCS(=O)(=O)c2ccc(F)cc2)c1C +COc1cc2nc(COCC(F)(F)F)[nH]c(=O)c2cc1OC +CCn1nc(C(=O)NC(C)C)c(=O)c2ccccc21 +CCOC(=O)C(C)NC(=O)CN(C)C(=O)c1ccccc1 +Cc1cc(=O)oc2cc(OCC(=O)N3CCc4ccccc4C3)ccc12 +CC(=O)N1CCN(c2oc(C=Cc3ccccc3)nc2C#N)CC1 +CCn1cc(CNC(=O)C23CC4CC(CC(C4)C2)C3)c(C)n1 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1ccsc1 +CNC(=O)C(CC(C)C)NC(=O)NCc1ccc(C)cc1N(C)C +CNC(=O)CNc1cccc(C(=O)N2CCCC2)c1 +CC(NC(=O)c1ccoc1)C(=O)NC1CCc2ccc(F)cc21 +Cc1c(C(=O)Nc2ccc3ccccc3c2)cnn1-c1ccccn1 +Cc1ccccc1N1CCN(C(=O)C2CCC2)CC1=O +O=C1N(Cc2ccccc2F)c2ccccc2C1(O)c1ccccc1 +CCc1cc(C(=O)N(Cc2ccco2)CC2CCCO2)sc1C +CCCCC(=O)NCc1nc(-c2ccccc2C)no1 +Cc1ccccc1CC(=O)N1CCN(Cc2cn(C)nc2C)CC1 +Cc1ccc2nc(COC(=O)c3ccc4c(c3)OCCCO4)cn2c1 +Cc1cc(Cl)ccc1S(=O)(=O)NCc1ccoc1 +CCC(C)N(C(=O)Cc1ccccn1)C1CCCC1 +COc1ccc(CNC(=O)c2ccnn2C(F)F)cc1OC +CCCNC(=O)c1cccc(C(=O)Nc2ccc(C)c(C(N)=O)c2)c1 +Cc1ccc(C(=O)Nc2cccn3nc(C(C)C)nc23)cc1 +CCCOC(=O)CN1C(=O)C(CC)Nc2ccccc21 +COCCNS(=O)(=O)c1ccc(NC(C)C)nc1 +NC(=O)CN(C(=O)Cc1cnn(-c2ccccc2)c1)C1CCCC1 +CCN(CC)S(=O)(=O)c1ccc2c(c1)CN(CCN)CC2 +COCCn1cc(NC(=O)N2CC(C)OC(C)C2)cn1 +O=C(CCCc1nc2ccccc2c(=O)[nH]1)NCc1cccnc1 +COc1ccc(CN(C)C(=O)CNc2ccccc2F)cc1OC +OCC1CN(c2ccc(F)cc2)C(c2ccccn2)O1 +COc1ccccc1OCC(O)CNc1ccccc1C +Cc1nc2ccccn2c1C(=O)NCC(O)c1cccs1 +O=C(Nc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1)C1CCC1 +O=C(OCCn1cncn1)c1cnn(Cc2ccccc2Cl)c1 +CC(Nc1c(C#N)c(=O)n(C)c(=O)n1C)C(C)n1cccn1 +Cc1ccccc1CN(C)C(=O)c1cnn(-c2ccncc2)c1C +Cn1ccnc1Cn1c(CC#N)nc2cc(F)ccc21 +COCc1ccccc1C(=O)N(C)CC(F)(F)F +Cc1nnnn1C(Cc1ccc(F)cc1)C(=O)N1CCCC(C)C1 +CC1CCCC(C)N1C(=O)CSc1n[nH]c(N)n1 +O=C(CNC(=O)c1ccsc1)Nc1ccc(Br)cc1 +COc1ccc(OC)c(CC(=O)N(Cc2ccc(F)cc2)C2CC2)c1 +COc1cc(OC)cc(C(=O)NCCOc2ccccc2)c1 +COC(=O)C1CC(Oc2cccc(N(C)C)c2)CN1 +Cn1nnnc1SCc1cc(=O)n2cc(Cl)ccc2n1 +CS(=O)(=O)N1CCCC(C(=O)Nc2cccc(CO)c2)C1 +O=C(NCC1CC1)N(Cc1ccccc1)CC(F)F +Cn1c(=O)c2ccc(C(=O)OC3CCCCCC3)nc2n(C)c1=O +Cc1cccc(NC(=O)CCn2nc(C)cc2C)c1 +CN(C)C(=O)CN(C)S(=O)(=O)c1cccc(C#N)c1 +O=C(CNCc1cccs1)N1CCc2ccccc21 +CCCNC(=O)c1ccc(NC(=O)c2ccc(S(C)=O)cc2)cc1 +Cc1cc(C)c(C(=O)CNC(=O)c2ccco2)c(C)c1 +Cc1cccc(C(=O)NCc2cccnc2N2CCCC(O)C2)n1 +CCc1ccccc1OC1CN(S(=O)(=O)NCc2ccccc2)C1 +CCOc1ccc(NC(=O)CNC(=O)NCC(=O)N2CCCC2)cc1 +CC(NCc1cncs1)c1cccc(OC(F)F)c1 +CCc1noc(CN2CCN(C(=O)c3ccc(F)cc3F)CC2)n1 +CC(Oc1ccccc1)C(=O)Nc1cc(F)cc(F)c1 +COc1cc(C)c(CCCn2cc(N)cn2)cc1Cl +CC(NC(=O)c1ccccc1)C(=O)OCc1ccccc1 +COC(=O)c1cnc(NC(=O)CCc2c[nH]c3ccccc23)s1 +COc1ccc(Br)c(C(=O)Nc2ccccc2C(C)=O)c1 +Cn1cnc(S(=O)(=O)NCC(=O)NCCc2cccc(F)c2)c1 +COc1cc(CC2(c3ccco3)NC(N)=NC2=O)cc(OC)c1OC +CNC(=O)COC(=O)CCC(=O)c1cccs1 +Cc1ccn(-c2cc(NCCNC(=O)c3cnccn3)ncn2)n1 +COCCOC(=O)C1CC(=O)N(c2ccccc2Br)C1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)Cc1csc(C)n1 +COCc1cc(-c2ccc(F)c(Cl)c2)ncn1 +CCCS(=O)(=O)NCCC1CNc2ccccc21 +CC(C)N(C(=O)CCc1ccccc1F)C1CCOCC1 +Cc1ccc(CCC(=O)N2CCCc3ccccc32)cc1N +O=C(Nc1cccnc1-n1cncn1)N1CCCC2CCCC21 +Cn1ncc2c(=O)[nH]c(CN3CCCN(c4nccs4)CC3)nc21 +CNC(=O)c1cccc(C(=O)N2CCCC(n3nc(C)nc3C)C2)c1 +COCCCNC(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +Cc1nn(C(F)F)c(C)c1CC(=O)NC1c2ccccc2CC1O +c1ccc(Cc2noc(CN3CCOC4CCCCC43)n2)cc1 +CCC(Nc1ncc(S(N)(=O)=O)s1)c1cc(F)ccc1F +CCCCN(CCO)C(=O)c1ccc(OC)c(Br)c1 +Cc1cc(C(N)=O)ccc1NC(=O)N1CCNC(=O)C1 +CC(C)CN1CCN(C(=O)CCn2cncn2)C(C)C1=O +CN(C(=O)C1CCCO1)c1c(N)n(Cc2ccccc2)c(=O)[nH]c1=O +Cn1nnnc1-c1cccc(NC(=O)c2ccc(-n3ccnc3)cc2)c1 +Cc1cnn(CCCNC(=O)c2nnc3nc(C)cc(C)n23)c1 +CCn1c(Cc2ccccc2)nnc1S(=O)(=O)Cc1noc(C)n1 +O=C(c1ccc(Cl)cc1)N(Cc1ccco1)Cc1ccco1 +N#CC(CCC(=O)NC1CC1)c1ccc(Cl)cc1 +CC(=O)Nc1ccc(C(=O)OCc2cc(=O)n(C)c(=O)n2C)cc1 +CCNC(=O)c1csc(-c2cc(Br)cs2)n1 +Cc1cc(C2CCCN2Cc2noc(C3CC3)n2)on1 +COCC(C)NC(=O)c1sc(-c2ccc(F)cc2)nc1C +CCc1noc(CC)c1CC(=O)NCc1ccnc(-n2cccn2)c1 +CC(C)C(CNC(=O)COc1ccccc1C#N)N1CCOCC1 +O=C(CCc1cnn(-c2ccccc2)c1)NCCCO +O=C(CNC(=O)c1ccc(F)cc1)Nc1ccc2c(c1)OCCCO2 +O=C1CCC(NCc2ccncc2)C(c2cc(F)cc(F)c2)N1 +O=C(COc1cccc(Cl)c1)NCCc1ccc2c(c1)OCCO2 +COc1ccc(OC)c(C2(C)CN(C)C(=O)O2)c1 +COC(=O)CCCc1nc(CN2C(C)COCC2C)no1 +Cc1nn(C)c2ncc(NC(=O)N3CC(C)CC(C)C3)cc12 +CCOCC1CCCN(C(=O)Cn2nc(C)c3ccccc3c2=O)C1 +CC(Sc1cc(C#N)ccn1)C(=O)Nc1ccc(C#N)c(Cl)c1 +COCc1cccc(NC(C)c2cccc(O)c2)c1 +N#Cc1cccc(CN2CCN(c3nccs3)CC2)c1 +Cn1cc(C(=O)CSc2ccc(F)c(F)c2)cn1 +COc1cccc(C(=O)Nc2ccc(CN3CCOC3=O)cc2)c1F +Cc1cc(N2CCCC2=O)ccc1S(=O)(=O)NCC1CC1 +Cc1cccc(N)c1NC(=O)c1ccc(F)c(F)c1 +Nc1ccnc(CN2CCc3ccc(Cl)cc3C2)n1 +COC(=O)C1(N(C)C(=O)C2CCC(F)(F)CC2)CCCCC1 +O=C(Nc1ccc(F)cc1)C1C2CC3OC(=O)C1C3C2 +COc1ccc(CNC(=O)c2ccc(S(N)(=O)=O)cc2)cc1 +CCOC(=O)c1cc(-c2cc(C)ccc2SC)nn1CCO +COC(=O)C1(N(C)C(=O)c2cc(C)no2)CCCCC1 +CN1CC(C(=O)NCCOc2cccc3ccccc23)CC1=O +N#Cc1ccc(-c2cnc(N3CCOCC3)s2)cc1 +CC(C)COc1ccc(C(=O)N2CC(C)OC(C)C2)cc1 +CCC(C)NC(=O)C(C)S(=O)(=O)c1ccc(C)c(C)c1 +O=S(=O)(Cc1n[nH]c(C2CC2)n1)c1ccc(Cl)cn1 +Cc1csc(NC(=O)c2nc3ncc(Br)cn3n2)n1 +CCCOC(=O)Cn1cnc2sc3c(c2c1=O)CCC(C)C3 +Cc1cccc2nc(-c3ccccc3Br)nn12 +COc1ccc(S(=O)(=O)CCCO)cc1Cl +Cc1cc(C)c(NC(=O)CNC(=O)CC2C=CCC2)c(C)c1 +O=C(Nc1nc(C(=O)N2CCc3ccccc32)co1)c1ccccc1 +Cc1cc(C(F)F)nn1CC(=O)Nc1cccc(Br)c1 +CC(=O)c1ccc(O)c(CSc2ncccn2)c1 +COC(=O)CN(Cc1sccc1Br)C(C)C +CCSc1nnc(NCC(=O)c2ccc(C)cc2)s1 +NC(=O)c1csc(C(=O)NCc2cccs2)c1 +CCCCNC(=O)c1ccc(=O)n(Cc2ccccc2Cl)c1 +CCCn1nc(C(=O)NC(C)c2cccc3ccccc23)ccc1=O +CC(C)(C)c1nnc(NCc2cccc3cn[nH]c23)o1 +COc1cccc(-c2n[nH]c3c2CN(Cc2ccccn2)CC3)c1 +CCC(CC)NC(=O)N(C)Cc1ccc(C(N)=O)cc1 +Cc1ccc(-c2c(CO)nnn2Cc2c(C)noc2C)cc1C +Cc1cccc(CN2CCSc3ccc(N)cc32)c1 +COc1ccc2c(=O)c(C(=O)Nc3ccccc3)c(N)oc2c1 +CC(C)(C)c1ccc(CN2C(=O)CCC2C#N)cc1 +Cn1ncc(C(=O)Nc2ccc3cc[nH]c3c2)c1-n1cccc1 +COC(=O)C=c1sc2n(c1=O)CN(C(C)C)CN=2 +O=C(NCCn1ccc(C(F)(F)F)n1)NC1CCCCCC1 +O=C(c1cccc(F)c1)N1CC(OCc2cccnc2)C2COCC21 +CCOC(CCNC(=O)Nc1ccc2c(c1)COC2)C1CCCC1 +COC(=O)C(C)NC(=O)c1cc(Br)c2c(c1)OCCO2 +COC(=O)c1ncn(Cc2cn3c(C)cccc3n2)n1 +CC(C)c1ccsc1C(=O)N(C)CC(=O)N1CCOCC1 +COC(=O)Nc1ccc(NC(=O)c2cnc3ccc(C)cn23)cc1 +Cc1ncccc1-n1cccc1C(=O)Nc1ccc(Cl)cc1 +Nc1csc2nc(-c3ccccc3Cl)nn12 +CC(C)N1CC(C(=O)Nc2ccc(CNC(N)=O)cc2)CC1=O +Cc1ccccc1SC1CCN(C(=O)c2cccc(C#N)c2)CC1 +O=C(NC1CC1)c1cccnc1Oc1ccccc1 +CCCOc1ccc(NC(=O)c2cnccn2)cc1Cl +N#Cc1ccc(Oc2cc(-n3cccn3)ncn2)cc1 +CC(C)CC1Nc2ccccc2C(=O)N1CC(=O)Nc1nccs1 +COc1ccc2c(C)c(C(=O)NCCCc3ccco3)oc2c1 +CC1Oc2cccc(N)c2N(CC(=O)NC2CCCC2)C1=O +CC=Cc1ccc(OCC(=O)N(C)C(C)C)c(OC)c1 +CCC(C)OC(=O)C(C)n1c(=O)oc2cccc(N)c21 +CCC(=O)Nc1cccc(NCC(=O)N(C)c2ccccc2)c1C +COC(=O)c1ccoc1COC(=O)c1sc(C)nc1C +COC(=O)c1cccc(NC(=O)c2nccc3ccc(N)cc23)c1 +CSc1ccc(NC(=O)C(C)OCC2CCCO2)cc1 +CCOC(=O)C1CCCN(C(=O)NCc2noc3ccc(C)cc23)C1 +O=C(c1cncc(F)c1)N1CCCC1c1nc(-c2ccccc2)n[nH]1 +O=c1cc[nH]c(C2NCCc3c(OC(F)F)cccc32)c1 +CCc1nc2n(n1)CCCC2NC(=O)CCCc1cc(F)ccc1F +Cc1cccc(CCC(=O)C(C#N)c2nc(C)cc(C)n2)c1 +CCN1CCOC(CC(=O)Nc2cccc(C(F)(F)F)c2)C1=O +CC1CN(C(=O)CCCNC(=O)c2ccccc2)c2ccccc21 +CC(C)Cc1nc(CS(=O)(=O)c2ccc(C(F)(F)F)cn2)no1 +O=C1CC(Cc2ccccc2)CN1Cc1cncnc1 +CN(C)C(=O)c1ccc(CN2CCN(c3cc(F)ccc3F)CC2)[nH]1 +CC1(C)C(=O)Nc2ccccc2N1C(=O)COc1ccc(C#N)cc1 +COC(=O)CNC(=O)CCc1ccc(Br)c(C)c1 +CS(=O)(=O)c1ccc(NC(=O)CCNC(=O)c2ccco2)cc1 +COc1cc(F)ccc1NCc1nc(-c2ccccc2)no1 +CCN(C)C(=O)c1cccc(OC(=O)C(C)c2c(C)noc2C)c1 +CCn1c(C)cc(C(=O)Cn2c(C)cc(C)c(C#N)c2=O)c1C +Cn1cc(-c2nc(-c3nc(-c4ccncc4)no3)cs2)cn1 +CCC(C)C(=O)N1CCCC(C(=O)NCC(C)(C)c2ccncc2)C1 +Cc1cc(=O)c2cccc(F)c2n1CC(=O)Nc1ccc(C#N)cc1 +CCN1CC(C(=O)NCC(c2ccccc2)c2ccccc2)CC1=O +NS(=O)(=O)NCc1ccc(Cn2ccccc2=O)cc1 +O=C(c1ncncc1Cl)N(CCO)CCc1ccccc1 +Cc1ccc(C(O)CNC(=O)c2cccc(Br)c2)o1 +Cc1ccc(Cl)cc1N1CC(C(=O)NC(C)C)CC1=O +Cc1cc(NCC(=O)NCc2ccccc2)nc(C)n1 +O=C(CCOCC1CCCO1)Nc1ccc2c(c1)CCC(=O)N2 +CNC(=O)c1cccc(CN(C2CC2)S(=O)(=O)c2cccnc2)c1 +Cn1cc(-c2nn(-c3ccccc3)c3c2CNCC3)nn1 +NC(=O)c1cccc(NC(=O)c2cnn(Cc3ccccc3)c2)c1 +Cc1cc(NC(=O)CN2C(=O)c3ccccc3CS2(=O)=O)no1 +Cc1ccc(OCCCC(=O)Nc2ccc(C(N)=O)cc2)c(C)c1 +CCC(CC#N)NC1CCSc2ccc(Cl)cc21 +CC(C)COC1CCN(C(=O)c2cn(Cc3ccccc3)nn2)CC1 +CCN(CC)C(=O)C1CCCN1C(=O)c1ccc(C)[nH]c1=O +Cn1cccc1CN(C(=O)NCc1ccc(F)cc1)C1CC1 +O=S(=O)(Cc1ncc(-c2ccccc2)o1)c1ccccc1 +CCC(C)NC(=O)CCNc1cc2ccccc2c(=O)[nH]1 +O=C(Nc1nnc(C2CC2)s1)c1cccnc1OCC(F)F +CC(C#N)C(=O)Nc1ccc(Oc2ccccc2)cc1 +O=C(Nc1nccs1)c1ccc(Br)cc1Cl +CCC(O)CN1CCN(C(=O)CCC2CCCO2)CC1 +O=C(NCCc1ccncc1)c1ccccc1NCc1cccs1 +CN(CC(=O)Oc1ccccc1F)S(=O)(=O)c1ccc(F)cc1 +O=C(CCn1cnnc1)N1CCN(c2nc3ccccc3s2)CC1 +COC(=O)N1CCC(NC(=O)c2nc(-c3ccco3)sc2C)CC1 +COc1ccc(Cl)cc1C(O)c1cccs1 +Fc1ccc(-c2cnc(SCc3nc(C4CC4)no3)[nH]2)cc1 +CC1CCN(C(=O)c2c(F)cccc2Cl)C(C)C1 +Cc1ccc(-c2nccn2CCCO)c(Cl)c1Cl +O=C(c1ccoc1)N1CCN(C(=O)c2cc3c([nH]c2=O)CCC3)CC1 +CC(C)n1nccc1NC(=O)NCCS(=O)(=O)c1ccccc1 +Cc1cc(C)nc(N2CCC(Oc3cnccn3)CC2)n1 +CNC(C)(C(N)=O)c1ccc(S(C)(=O)=O)cc1 +Cc1cc(NC(=O)CC2CCCN(C(=O)NCC(C)C)C2)n(C)n1 +CC(Sc1ccccc1)C(=O)N1CCN(c2ccc(O)cc2)CC1 +Oc1c(F)ccc2c1CCNC2c1c(F)ccc(F)c1F +CC(C)(C)NC(=O)NCc1cc2n(n1)CCCN(C(=O)C1CCC1)C2 +COc1nn(C)cc1C(=O)N1CCc2nc(NC(C)=O)sc2C1 +COc1cccc(N2CC(NC(=O)N3CC(C)OC(C)C3)CC2=O)c1 +Cc1ccc2c(c1)C(O)(CC(=O)c1ccccc1C)C(=O)N2 +COCCNC(=O)NC1(C(F)(F)F)Oc2ccc(Cl)cc2O1 +Cc1cccc(OCCCC(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +COc1ccccc1-n1cc(S(=O)(=O)N(C)C(C)C(N)=O)cn1 +O=C(NCc1ccc(-n2cncn2)nc1)c1ccc(Cl)c(Cl)c1 +CCNC(=O)c1snc(-c2c(F)cccc2Cl)c1N +Cc1noc(COCC(=O)NCC(C)(O)c2ccsc2)n1 +CC(NC(=O)n1ccnc1)c1ccc(Cl)cc1Cl +CS(=O)(=O)c1ccc(Cl)c(NC(=O)c2ccncc2)c1 +CCc1cc(N)nc(-c2cccc(OC)c2OC)n1 +Cc1cc2c(c(=O)[nH]1)C(=O)OC2=Cc1c[nH]nc1-c1cccs1 +CCn1cc(NC(=O)c2cccc3[nH]ccc23)cn1 +CCOCC1CCCN(C(=O)CCc2ccncc2)C1 +Cc1nn(C)cc1C(=O)Nc1ccc2c(c1)nc(C(C)(C)C)n2C +Cc1ccc2nc(SCC(=O)N3CCC3)[nH]c2c1 +COc1ccccc1C(C)N1CCN(Cc2cncs2)CC1 +CCc1n[nH]c(SCCn2c(=O)oc3cccnc32)n1 +CC1CN(C(=O)c2ccc(NC(=O)c3cccnc3)cc2)CC(C)O1 +CCOc1ccc(NC(=O)NCC(=O)OC(C)C)cc1C +CS(=O)(=O)NC1CCN(C(=O)C2CCCc3ccccc32)CC1 +CN1CCOc2ccc(NC(=O)NC3CC3)cc2C1=O +CCc1noc(CC)c1CNC(=O)CSc1ccccc1 +CCC1CN(C)c2ccccc2CN1C(=O)c1cc(C#N)c[nH]1 +Cc1noc(C)c1CN1CC2CC(C1)N(Cc1nccs1)C2 +COCc1nn2cc(-c3cc(C)ccc3C)nc2s1 +CN(CC(=O)Nc1ccccc1Cl)C(=O)c1c[nH]c2ccccc12 +Cn1c(=O)[nH]c(=O)c2cc(C(=O)N3CCCc4ncccc43)cnc21 +CC(C)(CNC(=O)Nc1cccc(Cl)c1F)NS(C)(=O)=O +CCOC(=O)CNC(=O)NCc1c(C)nn(C)c1C +Nc1c[nH]c(C(=O)Nc2nc3c(s2)CCCC3)c1 +O=C(Nc1cccnc1-n1cccn1)c1coc(-c2ccccc2)n1 +CCOc1ccc(C(=O)Nc2c(C)nc3sccn3c2=O)cc1 +COc1ccc(C(=O)CNc2ccccc2OC)c(OC)c1 +CC(NC(=O)c1ncoc1-c1ccc(F)cc1)c1ccncc1 +CN(CCO)c1ncc(Br)c2cc(F)cc(F)c12 +Cc1ccccc1C1CC1C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +N#CC(NCc1ccc2c(c1)OCO2)c1ccco1 +CCC(=O)N(CCOC)c1nnc(-c2ccc(F)cc2)s1 +COc1ccc(NC(=O)CN(C)C(=O)Cc2c(C)nn(C)c2C)cc1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)Nc1ccc2c(c1)OCO2 +Cc1cccc(CS(=O)(=O)c2nnc(NCC(C)C)s2)c1 +CCn1c(C)cc(C(=O)N2CCCN(c3nc(C)cs3)CC2)c1C +O=C1CC2(CCCCN2C(=O)c2ccccc2)CN1CC1CC1 +CNC(=O)c1ccccc1C#CCNC(=O)c1cccc(N(C)C)c1 +CC(=O)NCCNC(=O)CC(c1ccccc1)c1cccc(Cl)c1 +C#CCNC(=O)CCNC(=O)c1cc(F)cc(F)c1 +O=C(c1c[nH]c2ccccc12)N1CCC(Oc2cccnn2)CC1 +CC(Oc1ccc(C(N)=O)cc1)C(=O)N1CCCCCC1 +COC(=O)c1ccc(NC(=O)c2ccccc2C)cc1OC +COc1ccc(N)cc1NC(=O)COc1ccccc1F +Cc1ccc(CNC(=O)CNS(=O)(=O)c2cn(C)cn2)cc1F +CCNC(=O)CN1CCN(CCOc2ccccc2)CC1 +CC(=O)c1cccc(NC(=O)CN2CCCCCC2=O)c1 +Cc1ccccc1Oc1ncccc1CNC(=O)c1cnn(C)c1 +Cn1ccc(C(=O)N2CCN(Cc3ccccn3)CC2)cc1=O +CCCC(C)NC(=O)C(C)Nc1cccc(N2CCOC2=O)c1 +N#Cc1ccc(CN2C(=O)c3ccccc3CS2(=O)=O)c(F)c1 +CC(=O)N(C)CC(=O)Nc1nc(-c2ccc3c(c2)CCCC3)cs1 +Cn1nnnc1-c1cccc(NC(=O)Cc2cccc(F)c2)c1 +CN(C(=O)CCNS(=O)(=O)c1ccccc1)C1CCCCC1 +COc1cccc(C2CN(Cc3cnc4ccc(C)cn34)CCO2)c1 +CCS(=O)(=O)c1ccc(Cl)cc1CNc1ccc2[nH]ncc2c1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)C1CCCC1 +Cc1c(C(=O)Nc2ccc3c(c2)CCC3)[nH]c2c1C(=O)CCC2 +Cc1cccc(OS(=O)(=O)c2cccc(S(C)(=O)=O)c2)c1C +C#CCOc1cccc(NC(=O)C2CCCCN2S(C)(=O)=O)c1 +COc1ccc(CNC(=O)c2ccc(N3CCOC3=O)cc2)cc1 +Cc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c(=O)n1C +COC(=O)c1ccc(C(=O)NCC(F)(F)F)s1 +c1ccc2[nH]c(CCn3ccnc3-c3ccncc3)nc2c1 +COC(CNC(=O)N1CCC(n2cncn2)CC1)c1ccccc1 +CC(Cc1ccccc1F)NC(=O)c1nc2ccccc2c(=O)[nH]1 +CCc1nc(N)c2c(-c3ccccc3)csc2n1 +COC(=O)c1cc2ccccc2cc1OCC(=O)N1CCOCC1 +[H]N=c1n(CC=C)c2ccccc2n1CCOc1ccccc1OC +C#CCNC(=O)CSc1nnc(N)n1C(C)C +COc1ccc(C)cc1NC(=O)CCCNC(=O)NC1CCCCC1 +CC(C(=O)Nc1ccccn1)N1C(=O)c2ccccc2S1(=O)=O +COc1ccc(Cl)cc1NC(=O)c1cc(C(N)=O)cn1C +CN1CCC(NC(=O)COc2ccc(Cl)cc2)C1=O +CNS(=O)(=O)c1ccc(C(C)NC(=O)CCC(C)C)cc1 +O=C(c1ccco1)N1CCC2C1CCN2S(=O)(=O)C1CC1 +Cc1nnc(N2CCOCC3(CCCN(C(=O)c4ccoc4)C3)C2)o1 +CCC(=O)N1CCC(S(=O)(=O)c2ccc(F)cc2)CC1 +COc1ccccc1NCC(=O)N1CCc2ccccc21 +CCC(CC)C(CNC(=O)c1ccc2c(c1)OCO2)N1CCOCC1 +Cc1cc(C)nc(N2CCN(c3cc(C#N)ccn3)CC2)n1 +CN(C)c1ccccc1NC(=O)CNC(=O)C1CCCC1 +O=C(NC1CC1)C1CCCN1C(=O)c1ccncc1 +O=C1NCCNC1CC(=O)N1CCC(Cc2ccccc2)CC1 +O=C(NCC(O)c1cccc2ccccc12)Nc1cccs1 +N#CCCn1c(-c2ccccn2)nc2cc3c(cc21)OCCO3 +CC(C)(CNC(=O)CCC(=O)c1cccs1)c1ccncc1 +Cc1c(C(C)NC(=O)Nc2cnn(CC(F)(F)F)c2)cnn1C +COc1ccc(C(C)=O)c(OC(=O)c2cnc3ccc(C)cn23)c1 +CCC(C)(C)NC(=O)CN(c1ccc(C#N)cc1)S(C)(=O)=O +CCCn1ccc2ccc(NC(=O)N(C)Cc3ccncc3)cc21 +CN(CCc1ccccn1)S(=O)(=O)c1cc(F)c(F)cc1F +CC(=O)Oc1c(Br)c(=O)oc2ccccc12 +N#Cc1cnn(-c2ncnc3sc4c(c23)CCC4)c1N +Cc1cnc(NC(=O)c2sccc2-n2cccc2)s1 +CC(C)CNC(=O)CSc1nnc(-c2ccc(Cl)cc2)n1C +CN(CCc1cccc2ccccc12)Cc1cnc2ncccn12 +CC(C)C(C(=O)N1CC(O)C1)c1ccc(Cl)cc1 +Cc1ccc(CC(C)NC(=O)C2CCN(c3cnccn3)CC2)s1 +COc1ccc(C(=O)C(C)Oc2ccc(C)cc2N)c(OC)c1OC +CC(O)CNC(=O)CC1Oc2ccccc2NC1=O +CCn1ccc2ccc(CCC(=O)NCC3CC3)cc21 +Cc1nn(CC(=O)Nc2cccc3c2C(=O)NC3)c(C)c1Cl +O=C(Nc1ccccc1CN1CCc2ccccc21)C1COCCO1 +O=C(CCn1ccnn1)N1CCCC1c1noc(C2CC2)n1 +Cn1cc(Nc2c(F)c(F)c(F)c(F)c2F)cn1 +Cc1cc(NC(=O)CN2CCCc3cc(F)c(F)cc32)no1 +O=C(c1ccc(N2Cc3ccccc3C(O)C2)nc1)N1CCCCC1 +N#Cc1ncn(Cc2nnc(-c3ccccc3Br)o2)n1 +Cc1n[nH]c(C)c1N1CCN(Cc2cccs2)CC1 +O=C(CCc1cncc(F)c1)Nc1ccc(-c2ccccc2)nn1 +CCN(CC)C(=O)c1ccc(NC)c(C(F)(F)F)c1 +C#CCNC(=O)N1CCN(C(=O)c2c(F)cccc2Cl)CC1 +O=C(COc1ccc2c(c1)oc(=O)c1ccccc12)Nc1cccnc1 +COc1ccc(OCCN(C)C(=O)NCC(C)C)cc1 +Cc1cc(N)ccc1NC(=O)CCCn1ccccc1=O +Cc1ccc(-n2cc(C)cn2)c(NC(=O)c2scnc2C2CC2)c1 +O=C1CCC(C(=O)N(CCc2ccccc2)Cc2ccncc2)CN1 +CCCCN(C)C(=O)c1ccc(S(=O)(=O)N2CCOCC2)cc1 +CC1(C)CNC(=O)c2nc(-c3cccc(-n4cccn4)c3)[nH]c2C1 +C#CCNC(C(=O)c1c[nH]c2ccccc12)c1ccccc1 +Cc1cc2oc(=O)cc(C)c2cc1OS(=O)(=O)N(C)C +Cc1ncc(C(=O)NCC(O)c2cccc(Oc3ccccc3)c2)cn1 +Cc1cc(C(N)=O)ccc1NC(=O)c1ccccc1F +Cc1ccc(C)c(S(=O)(=O)NCCNC(=O)c2ccsc2)c1 +COC(=O)CN(C(=O)c1csc(-c2ccc(C)cc2)n1)C(C)C +COc1ccc(Cc2nnc(NC(=O)CC(C)C)s2)cc1OC +CC1CCN(C(=O)c2ccc(-c3ccccc3)nc2N)CC1 +COC(=O)c1c(C)cccc1S(=O)(=O)N(C)c1ccccc1 +COc1ccc(F)cc1NC(=O)C1CCC(=O)NC1 +N#CCCN(Cc1cccnc1)C(=O)Cn1cnc2ccccc2c1=O +Brc1ccccc1CCc1ncn[nH]1 +CC1CCCN(C(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2)C1 +CC(C)(C)c1cc(NC(=O)COc2ccccc2F)no1 +COc1cc(C(=O)NCc2n[nH]c3c2CCC3)nc(OC)n1 +COc1ccc(F)cc1NC(=O)c1ccc(-c2ccco2)[nH]c1=O +CNS(=O)(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 +CCC(C(=O)NCc1cccc(OC)c1)c1c(C)noc1C +COCCn1cnnc1SCc1cc(C)cc(C)c1 +CNC(=O)C1(NC(=O)c2cccs2)CCCCC1 +CCN(c1ccc(OC)c(N)c1)S(=O)(=O)N(C)C +O=C(CO)N1CCCC(CCc2cccc(C(F)(F)F)c2)C1 +Cn1cnc(CNC(=O)Nc2ccccc2-c2cccs2)n1 +COC(=O)C(C)n1ccnc1Cc1ccc(OC)c(OC)c1 +COCCNc1nc(-c2ccc(C)cc2)c(C)cc1C#N +CCOC1CCCN(C(=O)c2cc(N)ccc2Cl)C1 +O=C(Nc1cccc2cccnc12)N1CCOC(CO)C1 +CCOc1ccc(C2=CCN(C(=O)c3cnc(CC)s3)CC2)cc1 +CCS(=O)(=O)N1CCC(O)(CNc2ccccc2)CC1 +CC(C)OC(=O)CCn1ncc(=O)c2ccccc21 +COc1ccc(Cl)cc1CN(C)C(=O)NCc1cnc(C)s1 +COc1ccc(CNC(=O)c2coc(-c3ccccc3)n2)cc1 +Cn1c(=NC(=O)CCNC(=O)c2ccco2)sc2ccccc21 +O=C(CCc1ccccc1)N1CCC2C1CC(=O)N2c1ccsc1 +CCCNC(=O)CNC(=O)C12CC3CC(CC(C3)C1)C2 +COc1ccc(C)cc1NCC(=O)N(C)c1ccccc1 +O=C(Cc1ccc(O)cc1)NCC1CN(Cc2ccccc2)CCO1 +CCC(OC)C(=O)NCCN1CCc2ccccc21 +CCC(=O)Nc1nnc(-c2ccc(SC(C)C)cc2)o1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccc(-n2cnnn2)cc1 +CCOc1ccc(F)c(C(=O)Nc2cnn(CC(C)C)c2)c1F +CCCC(=O)Nc1ccc2c(c1)CC(C(=O)NC1CC1)CO2 +O=C(c1cnn2c1OCCC2)N1CC2CCC(C1)O2 +CCc1c(C)nc2n(c1=O)C(CC(=O)Nc1cc(C)ccn1)CS2 +Cc1ncsc1CN1CCCC(Nc2ncnc3c2CCC3)C1 +O=C(C1CC1)N(Cc1nnc(-c2ccc(Cl)cc2)o1)C1CC1 +Cn1cc(C(=O)N2CCC(c3nc[nH]n3)CC2)c(C(C)(C)C)n1 +O=C(Nc1ncn(CC(=O)N2CCCCCC2)n1)c1ccccn1 +Cc1ccc(Oc2cccc3c(=O)cc[nH]c23)cc1 +CCN(CC)C(=O)c1ccc(CN2CCOCC2)o1 +O=C(CCN1C(=O)c2ccccc2S1(=O)=O)N1CCOCC1 +CC(C)Nc1ccc(C(=O)N(Cc2ccco2)CC2CCCO2)cn1 +Cc1ccc(-c2nc(CC(=O)NC3CC3)cs2)o1 +N#Cc1ncn(Cc2nnc(C(=O)NCc3ccccc3)s2)n1 +CCc1onc(C)c1NC(=O)N1CCC(C(O)C(F)(F)F)CC1 +CCOCC1Oc2cc(N)c(Cl)cc2NC1=O +CCCc1cc(C(=O)Nc2c[nH]cc(Br)c2=O)[nH]n1 +Cc1ccc(C(=O)CNC(=O)Cc2cccs2)cc1C +N#Cc1ccccc1OCC(=O)Nc1nccs1 +Cc1ccc(-c2nccn2CCS(=O)(=O)N(C)C)c2cccnc12 +Cc1nn(-c2ccccc2)c(C)c1CN(C)S(C)(=O)=O +COc1cccc(OC)c1-c1nc2cc(N)cnc2o1 +COc1cccc(COCC(=O)N2CC(C)OCC2C)c1 +COc1ccc(-c2[nH]c(=O)c(C#N)c(C)c2C)c(OC)c1 +NC(=O)NCCc1ccc(C(=O)OCCC#Cc2ccccc2)cc1 +CCc1nccn1S(=O)(=O)c1cc(C(C)C)c(C)cc1OC +CCn1c(=O)n(CC(=O)N2CCn3c(C)nnc3C2)c2ccccc21 +Cn1c(=O)c2c(ncn2CC(=O)NCC2(CO)CC2)n(C)c1=O +COC(=O)N1CCC(NC(=O)c2ccc(F)c(C(F)(F)F)c2)CC1 +Cc1ccccc1C1CCCN1C(=O)c1ccc2c(c1)OCO2 +COC(=O)c1ccc(CNC(=O)NCC2CC2C)cc1 +Cc1ccc(S(=O)(=O)N2CCC(c3cn[nH]c3)CC2)cc1C(N)=O +CC(NC(=O)c1cc(C2CC2)nc2ccccc12)c1ccco1 +FC(F)(F)c1cccc(CC2CN(c3cnccn3)CCO2)c1 +Nc1cc(-c2nnc(NC(=O)c3ccco3)s2)ccc1F +Cc1noc2ncnc(N3CCC(Oc4ccc(Cl)cc4)CC3)c12 +COC(=O)c1ccc(C(=O)NCC(F)(F)F)cc1 +COc1ccc(C(=O)NCCN2CCN(C(=O)C(C)(C)C)CC2)cc1 +CC(C)Cc1nnc(NC(=O)NCc2cccc3cccnc23)s1 +Cc1sc(C(=O)NCCc2ccsc2)cc1N +Cc1ccccc1-n1ncc2c1N=C(O)CC21C(=O)Nc2ccccc21 +CC1CCC(NC(=O)CSc2ccc(C(F)(F)F)cn2)CC1 +CC(C)Cn1cc(C(=O)N2CCOC(C(N)=O)C2)c2ccccc21 +Cc1ccc(CNc2cc(-c3ccc(Cl)cc3)nn2CCO)nc1 +Cc1ccc(CCNC(=O)c2nnn(Cc3ccccc3)c2C)o1 +CCOC(=O)Cc1cc(OC)c(OC)cc1Br +NC(=O)c1cccc(CNC(=O)c2cccc(OCC(F)F)n2)c1 +N#Cc1cccnc1N1CCCN(C(=O)CCNC(N)=O)CC1 +CN(C(=O)c1ccc(OCC2CC2)nc1)c1ccc(Cl)cn1 +O=C(c1ccc(=O)[nH]c1)N1CCCC(CCc2c(F)cccc2F)C1 +CCC(NS(=O)(=O)c1ccccc1)C(=O)OC +Cc1nc(C(=O)Nc2nc[nH]n2)nn1-c1ccc(F)cc1 +CCC(C(=O)OC)c1ccc2c(c1)OCCCO2 +CCOc1ccc(C(=O)NC(C#N)c2ccccc2F)cc1OC +Oc1ccc2c(c1F)C(CSc1ncccn1)NCC2 +CCc1ccc(OC(C)(C)C(=O)Nc2ccon2)cc1 +CNC(=O)c1ccc(OC)c(NCc2csc(C)n2)c1 +N#Cc1cccnc1N1CCCN(C(=O)Nc2ccccc2F)CC1 +COC(=O)c1cc(COc2ccc3ccc(=O)oc3c2)oc1C +CC(C(=O)Oc1cccc(Oc2ncccn2)c1)c1ccsc1 +CCOC(=O)Cc1csc(NC(=O)c2cc3c(F)cccc3[nH]2)n1 +Cc1ccc(C)c(C(=O)CSc2nnnn2C)c1 +COCCN(Cc1ccco1)C(=O)Nc1ccncc1 +CC1CC(C)CN(C(=O)NCc2ccc(C(=O)N(C)C)cc2)C1 +CC(C)(C)OC(=O)N1CCC(C(=O)NCC(=O)N2CCCCC2)C1 +Cc1nc2ccccc2n1C(=O)c1ccc2c(c1)OCO2 +Cc1cc(NC(=O)C2CC3CCC2O3)ccc1C(=O)OC(C)(C)C +NC(=O)c1ccc(Cl)cc1OCC(=O)NC1CC1 +O=C(CN1CCN(c2ccc3c(c2)OCO3)C1=O)Nc1ccon1 +Cc1ccc(CNC(=O)c2cnc3sccn3c2=O)o1 +O=C(c1cccs1)N1CCN(C(=O)C2CC2c2cccs2)CC1 +Cc1c(Cl)cccc1NC(=O)N1CCN(CC(C)O)C(C)C1 +COc1ccc(NC(=O)Nc2ccc(F)cc2F)c(OC)c1 +CN(CCC#N)C(=O)Nc1ccc(-n2ccnn2)cc1 +CC(Oc1ccccc1C(N)=O)c1nc(-c2ccccc2)no1 +Cc1cc(C(=O)OCC(=O)C(C)(C)C)cc(S(N)(=O)=O)c1C +CC(=O)c1c[nH]c(C(=O)OCC(=O)Nc2cccc3ncccc23)c1 +O=C(NCCO)N(Cc1cccs1)c1ccc(F)cc1 +CCCCCn1c(CNC(=O)C2CC2)nc2ccccc21 +CC1CCCN(C(=O)COC(=O)Cc2ccc(Cl)cc2)C1 +C=CCN1C(=O)C(CC)(CC)N(C)c2ccc(N)cc21 +Cc1cc(C)c(C(=O)Nc2ccc(OC(F)F)c(F)c2)c(=O)[nH]1 +O=C(CCC(=O)N1CCOCC1)NCC1(c2ccccc2)CCCC1 +Cc1c(Br)cccc1C(=O)NCCc1n[nH]c(=O)[nH]1 +COc1ccc(OC)c(-c2cn3c(C)c(C#N)ccc3n2)c1 +CCn1c(C2CC(=O)N(c3cccc(Cl)c3)C2)nc2ccccc21 +CCCN(CCC)C(=O)c1cccc(OC)c1OC +Cc1cc(NC(=O)CNc2ccccc2SCC(C)C#N)n(C)n1 +O=C(NCCCNc1ccccc1)Nc1ccc2c(c1)COC2 +Cn1c(=O)c2ccc(C(=O)OCCc3ccccc3)nc2n(C)c1=O +CCS(=O)(=O)Nc1ccc(C(=O)NC2CC2)cc1 +Cn1c2ccc(N)cc2n2c(-c3ccccc3F)nnc12 +CS(=O)(=O)c1ccc(Cl)c(NC(=O)Cn2cnnn2)c1 +COCC1CCCN(C(=O)NCc2ccc(C)cc2N(C)C)C1 +CC(C)(C)NC(=O)CCc1nc(-c2cccs2)no1 +CC(C)c1n[nH]c(C2CN(C(=O)c3cc4c(s3)CCC4)CCO2)n1 +Cc1cc(CNC(=O)CCNC(=O)c2ccc(F)cc2F)c(C)o1 +C=CCn1c(SCc2nnc(CC)o2)nnc1-c1ccccc1 +CC(C)n1nnc(C#N)c1C(Cl)(Cl)Cl +COc1cc(CNC(=O)c2cc3sccc3[nH]2)ccc1O +COc1ccc(S(=O)(=O)N(C)Cc2ccc(C)o2)cc1 +Cc1ccc(NC(=O)C(C)OC(=O)c2[nH]nc3ccccc23)cc1 +CCCCN(C)C(=O)C1CSc2nccc(=O)n2C1 +COC(=O)c1cccc(OC(=O)c2cccc3cn[nH]c23)c1 +Cc1cc2c(=O)n(CCOc3ccccc3N)cnc2s1 +CCC(C)NC(=O)Cc1csc(Nc2ccccn2)n1 +CCc1noc(CC)c1CC(=O)Nc1ccccc1C(C)=O 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+O=C(Cc1cccc2cccnc12)N1CCc2sccc2C1 +O=C(C=C1NC(=O)c2ccccc2N1)c1ccncc1 +N#Cc1cc(CNc2ccc(CO)cc2)ccc1F +COc1ccc(-c2nn3c(-c4ccccn4)nnc3s2)cc1 +Cc1cc(CN(Cc2cc(C)no2)c2ccccc2)on1 +CCCNC(=O)C(N)c1ccc(C(F)(F)F)cc1 +O=C(NCc1ccccc1F)C1CC(=O)N(C2CCOCC2)C1 +O=C(Cn1nnc2ccccc2c1=O)Nc1ccc(F)c(Cl)c1 +COC(=O)c1cc(CNC(=O)C2CC3C=CC2C3)ccc1OC +O=C(Nc1ccc(C(=O)NC2CCCCC2)cc1)c1ccoc1 +Cc1ccc(C)c(N(C(C)C(=O)N2CCCCC2)S(C)(=O)=O)c1 +CC1CN(C(=O)CSc2c(N)cccc2Cl)CCO1 +Cn1cc(C2COC3(CCCN(C(=O)c4ccccc4)C3)C2)cn1 +O=C(CSc1ccccc1)N1CCOCC1C1CC1 +CCCN(CC(=O)N(C)C)C(=O)c1ccn(-c2ccccc2Cl)n1 +O=C(NCc1ccccc1C(F)(F)F)c1cnc2ccsc2c1 +CC1(CNS(=O)(=O)c2ccc(F)c(F)c2)CCOCC1 +CC(C)CCNC(=O)N1CCCC(C(=O)NCC2CC2)C1 +COC(=O)c1ccccc1C(=O)Nc1cnn(C2CCOCC2)c1 +O=c1c2ccc(F)cc2ncn1CC(O)c1ccccc1Cl +COC(=O)CCCOc1cc(F)cc(F)c1C(C)=O +O=C(Cc1ccc(F)cc1)Nc1ccc(CN2CCOCC2)cc1 +COC(=O)c1cc(Cl)ccc1-n1cnnc1C +CCc1onc(C)c1NC(=O)N1CCOC2(CCc3ccccc32)C1 +OCCSc1nnnn1-c1ccc(Br)cc1 +CC(C)S(=O)(=O)N1CC2CCCC(O)(c3cccc(F)c3)C2C1 +CCNc1nc(OC)nc(SCC(=O)Nc2ccccc2)n1 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+Cc1ccc(OC(C)C(=O)Nc2ccnn2Cc2ccco2)cc1C +N#Cc1cnc(NCCCN2C(=O)COc3ccccc32)c(Cl)c1 +COc1cc(OC)cc(-c2nc3n(n2)CCCC3C)c1 +OCC1NCCc2cc(O)c(OC(F)(F)F)cc21 +Cc1ccc2nc(CN3CCC(Oc4ncccn4)CC3)[nH]c2c1C +CCNC(=O)CN(CC)S(=O)(=O)c1ccc2c(c1)CCC2 +CC(C)c1nnc(NCc2cc(F)cc(F)c2)o1 +NC(=O)c1ccccc1NCc1cc(Br)ccc1F +CC(C)C(=O)NCCNC(=O)CCc1ccc(F)cc1 +CC1CCc2c(sc(NC(=O)c3ccccn3)c2C#N)C1 +CCOc1ncccc1C(=O)NC(C)c1cc(OC)c(OC)cc1F +Cc1cccc(-c2nccnc2C2CCCN(Cc3ccncc3)C2)c1 +CCC(C)NS(=O)(=O)c1ccc(C(=O)N(CC)CC)cc1 +COCCn1cc(NC(=O)c2cccc(OC)c2O)cn1 +CNC(=O)c1ccc(SC(C)c2ccccc2F)nn1 +Cc1nc(-c2ccccc2)oc1CC(=O)N1CCCCC1 +COCC(O)CN(C)C(=O)c1cc(F)ccc1Br +CC(=O)c1ccc(NC(=O)C2CCCN2C(=O)C2CC2)cc1C +Cc1nc(C)c(C(C)NC(=O)CSc2nccn2C)s1 +CCC(CNS(N)(=O)=O)Oc1ccccc1F +CCCCN(C)C(=O)NCc1ccc(N2CCCCC2=O)cc1 +C=CCN(CC=C)C(=O)CCc1c(C)c2c(C)nn(C)c2[nH]c1=O +Cn1ncc2c(=O)n(CC(=O)Nc3ccc4[nH]ncc4c3)cnc21 +COc1cccc(N(C)S(=O)(=O)c2cccc(N)c2)c1 +Cc1cc(C(=O)Nc2ccc(C(C)(C)C)cc2)no1 +O=C(Cn1nc(-c2ccccc2Cl)ccc1=O)Nc1ccccn1 +CC(C)(C)c1nc2cc(NC(=O)NCC(=O)NC3CC3)ccc2o1 +COC(=O)CCCn1c(C(C)=O)nc2ccc(F)c(F)c21 +CCN(CC(C)(C)O)C(=O)CCC(=O)c1cc(C)sc1C +CCCCc1ccc(N2CC(C(=O)Nc3cc[nH]n3)CC2=O)cc1 +CCn1nc(CNC(=O)c2ccc3c(c2)OCO3)c2ccccc21 +CCOc1ccccc1CNS(=O)(=O)c1csc(C(N)=O)c1 +CCOC(=O)CN(C)C(=O)CCC1Cc2ccccc2NC1=O +CCN1C(=O)Cc2cc(NC(=O)COc3ccc(OC)cc3)ccc21 +Fc1ccc(OCC(F)(F)F)c(NCc2noc(C3CC3)n2)c1 +Cc1csc2ncn(C(CO)C(C)C)c(=O)c12 +O=C(NCCCO)NC1CC(=O)N(c2ccc(Cl)cc2)C1 +CC(COc1ccc(F)cc1F)NC(=O)NCC1CC1 +C#CCOCCC(=O)N(C)Cc1c(C)nc2sc(C)cn12 +O=C(NCCc1nc(-c2ccncc2)n[nH]1)Nc1ccccc1F +Cc1ccc(C(O)CNS(=O)(=O)c2ccc3c(c2)OCCO3)o1 +Brc1cnn(Cc2cc(-c3ccccc3)on2)c1 +Cc1ccc(CC(=O)N2CCN(C(=O)c3ccc(F)cc3)CC2)s1 +CCCNC(=O)C1CN(Cc2ccccc2)CCO1 +Cc1noc(Cn2nnc(-c3ccc(F)c(C)c3)n2)n1 +COc1ccccc1-c1c(CO)nnn1Cc1ccccc1F +c1ccc(-c2noc(CSc3nnnn3-c3ccccc3)n2)cc1 +COC(=O)c1noc(C(=O)N2CCCCCC2)c1N +O=C(NCCC1=CCCCC1)Nc1ccc(-n2ccnc2)nc1 +COc1ccc(NS(=O)(=O)c2ccc(SC)cc2)c(OC)c1 +O=C(C1CC(=O)N(C2CC2)C1)N1CCC(c2nnc3n2CCC3)CC1 +CS(=O)(=O)N1CCCC1c1nc(N)ncc1-c1cccc(F)c1 +CC(C)c1nc(C2CCCN(C(=O)c3ccc4[nH]ccc4c3)C2)no1 +FC(F)(F)c1nnc2ccc(NCCc3cccs3)nn12 +CCC(=O)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +CCOC(=O)C(C)NS(=O)(=O)N1CCC(C(C)(C)C)CC1 +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)N1CCN(c2ncccn2)CC1 +O=C(NCC1CC1)c1cc(-c2ccn(CC3CC3)n2)n2ccccc12 +CCCN(CCc1ccccn1)C(=O)c1cccc2c1OCCO2 +CCN(C(=O)CCn1ccccc1=O)c1cccc(F)c1 +O=C(NCc1ccc(-n2cnc3ccccc32)nc1)c1ccc(=O)[nH]c1 +CNC(=O)C1CCCCC1C(=O)N1CC(Oc2c(C)cccc2C)C1 +Nc1cc(C(=O)NC2CC2)ccc1Nc1ccccc1 +CC(=O)Nc1ccc(Nc2nc(C)cc(N3CCOCC3)n2)cc1 +Cc1ccc(CNC(=O)c2cnc(C)cn2)c(OCC2CC2)c1 +Cc1sc(-c2ccc3c(c2)OCCCO3)cc1CO +O=C1COc2ccc(NC(=O)C3CC4C=CC3C4)cc2N1 +N#CCOc1ccc(NC(=O)c2ccc(Cl)cc2F)cc1 +Cc1c(N)cc2c(=O)cc(C(=O)NC3CC3)oc2c1C +CCOC(=O)c1[nH]cnc1C(=O)N(CC)CC(F)(F)F +CC(C)Cc1cc(C(=O)Nc2cc(-c3nccn3C)[nH]n2)cc(=O)[nH]1 +Cc1nc2sccn2c1C(=O)NCC1(Cn2cccn2)CC1 +CC(NC(=O)N(C)Cc1cccc(Cl)c1)C(=O)N1CCCCC1 +Cc1c(C(=O)NCCCO)cnn1-c1ccc(Br)cc1 +O=C(c1nc2ccccc2s1)N1CCN(CCn2cccn2)CC1 +COc1ccccc1CCC(C)(C#N)N1CCOCC1 +CN(Cc1ccc(OC(F)F)cc1)C(=O)Nc1cccn(C)c1=O +Cc1cc(Cn2c(C)nn(C(C)(C)C)c2=O)no1 +Cc1ncc(CN2CCN(CC(=O)N3CCCCC3)CC2)s1 +COC(C)C(=O)Nc1ccc(-n2nc(C)cc2C)nc1 +CCN1CCOC(C(=O)NC(C#N)c2cccc(Cl)c2)C1 +CC(C)c1noc(-c2ccc(CNC(=O)c3ccsc3)s2)n1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCCc1cccc2cccnc12 +CC(C)S(=O)(=O)NCCNC(=O)c1ccco1 +O=C(NCC1CCCOC1)c1ccc2[nH]cnc2c1 +CCS(=O)(=O)NCCCNC(=O)Nc1cccnc1 +O=C(c1cccc(O)c1)N1CCN(c2nccs2)CC1 +COc1cc(C)ccc1NC(=O)Cn1c(=O)cnc2ccccc21 +CNC(=O)CN1CCN(C(=O)c2cn(C)nc2C(F)(F)F)CC1 +CN(Cc1cc[nH]n1)C(=O)c1ccc(-c2ccccc2Cl)o1 +Cc1ccc(NC(=O)NCc2cnn(C)c2C)cc1C(=O)NC(C)C +Brc1cccc(OCc2noc(C3CC3)n2)c1 +NC(=O)c1ccc(NC(=O)c2cc(Br)c[nH]2)cc1Cl +Cc1cc(OCCCn2ccc(N)n2)cc(C)c1Cl +Cc1cc(C)c(C(=O)NC(C)c2ccc(-n3ccnn3)cc2)c(C)c1 +Nc1ccc2[nH]c(-c3cc4c(s3)CCC4)nc2c1 +Cc1cc(NC(=O)c2cccc3ncccc23)n(-c2ccccc2F)n1 +CSc1nsc(SCC(=O)NC2CCCCC2)n1 +COC(=O)CCNC(=O)C1CNCc2cc(C)ccc21 +N#Cc1cccc(COc2cccc(CNc3cc[nH]n3)c2)c1 +CC1(C)OC(=O)c2c1ccnc2NCc1cccc(Cn2cncn2)c1 +CN(C)S(=O)(=O)c1cccc(COC(=O)c2ccc(C#N)cc2)c1 +O=S(=O)(Cc1ccccc1F)N1CCc2ccccc21 +OC1CCCN(c2ccnc(-c3cnc4ccccc4c3)n2)C1 +COC(=O)C(Sc1nncn1C)c1ccccc1C(F)(F)F +O=C(c1ccccc1Oc1ccccc1)N1CC(c2cccnc2)C1 +COc1c(C)cnc(CNC(=O)Nc2c(C)nn(C(C)C)c2C)c1C +COC(=O)N(C)c1ccc(NC(=O)N2CCc3ccccc3C2)cc1 +O=C(Cc1cccs1)NCCc1nc2c(s1)CCCC2 +O=c1c(C(F)(F)F)cccn1CCCn1cnnn1 +CC(C)OCCC(=O)Nc1nc(-c2ccc3c(c2)OCO3)cs1 +CC(C)N(CC1CC1)C(=O)c1cncc(Br)c1 +COc1ccc(C(C)n2nnc3ccccc32)cc1 +C=CCNS(=O)(=O)c1ccc(C(=O)NC(C)c2ccccc2)cc1 +Cc1ccc(COC(=O)c2sc3nc(C)[nH]c(=O)c3c2C)cc1 +Cc1ccc(C(=O)Cn2cnc3ccccc3c2=O)cc1 +C=C(C)CN(CC)C(=O)c1ccc2c(c1)NC(=O)CO2 +COc1ccc(C(C)NC(=O)c2scnc2C)cc1F +CCCOC(=O)CC1C(=O)NCCN1Cc1ccc(C)cc1 +COC(=O)N1CCC(NC(=O)Nc2cc(C)ccc2F)CC1 +Cc1oc2nc(SCC(=O)NCCCO)nc(N)c2c1C +CCn1cnnc1CNC(=O)CCNC(=O)c1ccsc1 +Cc1ccccc1CNC(=O)c1cc(NC(=O)c2ccco2)n(C)n1 +Cc1ccc(-c2noc(CCc3n[nH]c(C)c3C)n2)nn1 +CCOc1ccccc1NC1C(=O)Nc2ccc(F)cc21 +CN(C)c1ccc(C(=O)N(C)C2CCc3ccccc32)cc1 +CC(=O)C(NC(=O)COC1CCC(C)CC1)C(C)C +COc1ccc2c(C)cc3nnc(SCC(N)=O)n3c2c1 +COc1ccc(Cc2c[nH]c3cc(OC)c(OC)cc23)cc1OC +Cc1cccc(C(=O)NC(C)C(=O)N2CCc3cc(F)ccc3C2)c1 +Cc1cccc(NC(=O)N2CCN(CC(F)(F)F)CC2)c1 +COCCN(CCC#N)c1nc2ccc(N)cc2s1 +CC(=O)Nc1cc(NCc2cccc(C#N)c2)ccc1F +Cc1cnc(C(C)NCc2ccc(S(C)=O)cc2)s1 +O=S(=O)(NCc1ccc2c(c1)OCO2)c1ccc(Cl)cc1 +COC(CCc1ccc2c(c1)CCC2)(OC)OC +COc1ccccc1Oc1ccc(CCNC(=O)CC#N)cc1 +Cc1ocnc1-c1nnc2ccc(Br)cn12 +COCc1ccccc1C(=O)OCCn1c(=O)oc2ccccc21 +CC1CCCCC1NC(=O)CCc1nc(-c2ccsc2)no1 +CCc1nn(C)cc1CNC(=O)NC(CO)c1ccccc1 +CC(=O)Nc1ccc(C(=O)Nc2ccccn2)cc1 +Cc1nc(CC(=O)N2CCCC(Cc3ccccn3)C2)cs1 +COc1c(Cl)cccc1NC(=O)c1ccc(=O)n(C)n1 +Cc1nc(COc2ccc(N(C)S(C)(=O)=O)cc2)cs1 +O=C(OCCO)c1nc(-c2ccccc2)n2c1CCCCC2 +CCOC(=O)C1CCN(CC(=O)c2c(C)n(C)c3ccccc23)CC1 +O=C(NCC1CCN(C(=O)c2cccnc2)CC1)C1CCC1 +O=C(CCn1cccc1)Nc1ccc2c(c1)OCCO2 +CC1CC(OC(=O)c2cncc(Br)c2)C(=O)O1 +CC(=O)NS(=O)(=O)c1ccc(C(F)(F)F)cc1 +COc1ccc(CC(=O)N2CCOCC2)cc1F +CC(C)(C)OC(=O)N1CCC(COCc2cccnc2)C1 +COCCNCc1ccnc(-c2ccc(F)cc2)n1 +CN(C)S(=O)(=O)c1ccc(OCC(=O)NC2CCCC2)cc1 +COCc1cccc(C(=O)NCc2cccc(OC)c2)c1 +CC(C)(C)CN(CCC#N)Cc1ccccc1-n1cccn1 +CCOCc1ccccc1NC(=O)NCc1ccc(C(=O)NC)cc1 +FC(F)(F)CNc1nnc(SCC2CCCCO2)s1 +CCCCN(C)c1ncnc(Oc2ccccc2OC)c1N +CCOC(=O)N1CCC(C(=O)NCc2ccoc2)CC1 +Cc1nc(COc2ccccc2C(=O)NCC(=O)NC2CC2)no1 +CCc1nnc(CN(C)C(=O)CN2CC(c3ccccc3)CC2=O)o1 +O=C(Nc1ccc2oc(=O)ccc2c1)c1ccc(-n2ccnn2)cc1 +O=C(NCC1CC(=O)N(c2ccc(Cl)cc2)C1)c1ccco1 +Cn1cc(NS(=O)(=O)c2ccc(N)cc2Br)cn1 +C=C(C)Cn1c(NCCOC)nc2c1c(=O)n(C)c(=O)n2C +Cc1cncc(C(=O)N2CCOc3nc(C)ccc32)c1 +COCCCNC(=O)c1cc2ccc(OC(C)=O)cc2oc1=O +Cc1cc2cn(C3CC(O)C(CO)O3)c(=O)nc2o1 +CC(=O)Nc1ccc(NC(=O)c2cccc(NC(C)=O)c2)cc1 +Cc1ccc(NS(=O)(=O)c2cc(F)ccc2F)c(F)c1 +CCCC(C)NC1C(=O)Nc2ccc(Cl)cc21 +CC(C)N(C(=O)c1ccc(=O)n(C)n1)c1ccccc1 +CCC(C)NC(=O)C1CCN(c2ccc(C)cc2C)C1=O +O=S(=O)(NCC1(c2cccs2)CCCC1)C1CC1 +Cc1ccc(S(=O)(=O)N2CCN(c3cnccn3)CC2)cc1 +Cc1cc(C)cc(NC(=O)c2nc3c(n2C)CCCC3)c1 +CC1CN(C(=O)c2cc(O)nc3ccccc23)CCO1 +Cc1cc(NC(=O)Cc2csc(C)n2)c2ncccc2c1 +COc1ccc(C(C)CCNC(=O)c2cc[nH]n2)cc1 +O=C(NCCCn1ccnn1)c1csc(Cc2ccccc2)n1 +CC(C)(C)OC(=O)NC(C)(C)C(=O)Nc1cc(-c2ccncc2)n[nH]1 +COCc1ccc(CN2CCCCC2C(=O)OC)cc1 +Cc1nc(N(C)C)nc2c1COCC21CCN(C(=O)CCC(C)C)C1 +O=C(NCCc1cccs1)C1CCCN(C(=O)C2CC2)C1 +O=C(NCc1ccncc1)N1CCc2ccc(Br)cc21 +CN(Cc1noc(-c2ccccc2)n1)Cc1nc2ccccc2s1 +NC(Cc1ccccc1)C(=O)NCCC(F)(F)F +CCCNC(=O)CCCOc1ccc(Br)cc1 +O=C(COC(=O)c1nccc2ccccc12)NC1CCCC1 +CCN(CCO)C(=O)c1ccc(CSc2ncn[nH]2)cc1 +NS(=O)(=O)c1ccc(CNC(=O)NC2CCc3ccccc32)cc1 +CCn1nnnc1SCC(=O)Nc1ccc(NC(C)=O)cc1 +CN(C(=O)c1ccc(N2CCCOC2=O)cc1)c1ccccc1 +Cc1cccc(C(=O)Nc2ccc(C(=O)Nc3cccnc3)cc2)n1 +COC(=O)c1cc(OC)c(OC)cc1NC(=O)c1csc(C)c1C +Cc1ccc2oc(C(=O)N3CCC(O)CC3)cc2c1 +CC(=O)Nc1ccc(S(=O)(=O)NCCc2ccccc2)cc1 +O=C(NCCO)c1cccnc1SCc1ccc(F)cc1 +CCc1ccc(S(=O)(=O)Oc2cccc(C#N)c2)s1 +COC(=O)c1ncn(C)c(=O)c1OCc1ccccc1 +CC(C)CC(C)OC(=O)c1ccc(NC(N)=O)cc1 +CCOC(=O)N1CCN(C(=O)c2cccc(C#N)c2)CC1 +Cc1cc(C)cc(CNCC2CN(CC(C)C)CCO2)c1 +C#Cc1cccc(NCc2ccc(C(=O)N(C)C)[nH]2)c1 +COCC1CCCN(C(=O)c2ccc(Cn3ccnc3)cc2)C1 +c1ccc2c(c1)ncn2-c1ccc(CNc2ccc3nccn3n2)cn1 +Cc1nc(CC(=O)Nc2ccnn2Cc2ccccc2)cs1 +Cc1ccnc(NC(=O)Cc2cn3ccccc3n2)c1 +O=C1C(Br)=CN=CC1Br +COC(=O)c1cc(C)sc1NC(=O)Nc1ccncc1 +CC(C)(C)OC(=O)N1CCC(C#N)(c2ccccn2)CC1 +CCc1cccc(CC)c1NC(=O)Cn1ccc(C(F)(F)F)n1 +N#Cc1cccc(CSc2nnnn2C2CC2)c1 +Cc1ccc(OCc2cc(C(=O)NCCC3=CCCCC3)no2)cn1 +Cc1ccc(CC(=O)N2CCN(C(=O)c3ccc(O)cc3)CC2)cn1 +Cc1cccc(S(=O)(=O)CC(=O)Nc2cc(Cl)ccc2F)c1 +COCc1cc(CN(C)C(=O)c2cccc(-c3cn[nH]c3)c2)n[nH]1 +CCc1noc(CC)c1CC(=O)Nn1cnc2ccccc2c1=O +Cc1c(C(=O)Nc2ccnc3ccnn23)oc2ccccc12 +Cc1csc(NC(=O)CCc2cccc(Cl)c2)n1 +Cc1ccc(C)c(OCC(=O)Nc2c(C(N)=O)oc3ccccc23)c1 +CCCOCC(=O)Nc1ccc(-n2ccnc2C)nc1 +CN(Cc1ccco1)C(=O)NC1CCCCNC1=O +O=C(Nc1ccc2[nH]nnc2c1)c1cc(F)ccc1Br +COCCC(=O)C(C#N)c1ccc(OC(F)F)cc1 +Cc1cc(NCc2cnc(N3CCOCC3)nc2)ccc1F +CN(Cc1cc(Br)ccc1F)C(=O)c1ccncc1F +O=C(NCC1CC1)C1CC2CN(C(=O)NCC3CCCCC3)CC1O2 +CCCc1nnc(C(=O)N(C)Cc2cccnc2)o1 +N#Cc1ccc(CS(=O)(=O)c2ccc3ccccc3c2)cc1 +Cc1cc(N(C)C)nc(CNC(=O)Nc2ccc3c(c2)OCO3)n1 +O=C(NCc1ccsc1)c1ccc(Cn2cnnn2)cc1 +CCn1ncc(Br)c1C(=O)Nc1ccccn1 +NC(=O)c1nnsc1CC(=O)NCc1ccccc1F +CCNC(C(=O)OCC)c1cc(F)c(F)c(F)c1 +COc1ncc(NCc2csc(C)n2)cc1C(N)=O +COc1ccc(CC(=O)c2ccc(OCCO)cc2)cc1 +CCN(CC)S(=O)(=O)NC1CCN(C(=O)C(C)C)CC1 +c1cncc(-c2ncc(CN3CCCC(n4cccn4)C3)s2)c1 +COc1ccc(-c2nc(C)cc(=O)n2CC(=O)Nc2ccccc2)cc1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)N(C)CCOc1ccc(F)cc1 +Cn1nccc1CNC(=O)CNS(=O)(=O)c1cccs1 +Cc1cc(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)on1 +Cc1ccc(Oc2cc(CNC(=O)c3cnns3)ccn2)cc1C +CC1COCCN1C(C)C(=O)c1ccc(Cl)cc1 +Cc1ccccc1NC(=O)N1CCC2(CC1)OCCCO2 +CC(OC(=O)CCC(=O)N1CCOCC1)c1cc(F)ccc1F +CC1=Nc2nnnn2C(c2ccc(F)cc2)C1C(N)=O +NC(=O)c1ccc(C(=O)N2CCC(CCc3ccccc3)CC2)nc1 +Cc1nc(N2CCOCC2)[nH]c(=O)c1CCC(=O)Nc1ccccc1 +CC1(C(=O)NCc2nnc3ccccn23)CC1(Cl)Cl +CC(CNC(=O)NCC1CN2CCCCC2CO1)Nc1ccccc1 +CCc1nn(C)c(CC)c1CN1CCCN(c2ccc(C)nn2)CC1 +CC(=O)NC(C(=O)NCCCn1ccc2ccccc21)C(C)C +Cn1c(=O)[nH]c(=O)c2c1nc1n2CC(c2ccccc2)=N1 +COc1ccc(OC)c(NC(=O)CSc2nnc(C)o2)c1 +Cc1nc2ccccc2c(=O)n1-c1ccc(N)c(Cl)c1 +O=C(Cn1cnc2ccccc2c1=O)NCCCc1ccccc1 +COCC(=O)Nc1nnc(-c2ccncc2)s1 +NC(=O)Cc1ccccc1NC(=O)c1cccc(F)c1 +Cc1nc(C2CC3CCN(Cc4scnc4C)CC3O2)no1 +CCc1nnsc1C(=O)N(C)CCOc1ccccc1F +CS(=O)(=O)Nc1ccc2c(c1)ncn2CCc1ccccc1 +c1ccc(-c2nsc(NCc3ccnc(-n4cccn4)c3)n2)cc1 +COc1ccc2c(c1)C(NCCc1ccccc1)CCO2 +COC(=O)c1occc1CN1CCc2ccccc21 +CN1CCOCC12CCN(C(=O)N1CCCC1)CC2 +Cc1ccsc1CNc1c(C#N)c(=O)n(C)c(=O)n1C +CC(=O)c1ccc(C(=O)OC(C)Cn2cccn2)cc1 +O=C1CCc2cc(NC(=O)c3cccc(F)c3)ccc2N1 +Cc1ccc(Cn2c(C(=O)N3CCCC3)cc3occc32)cc1 +N#Cc1ccnc(N2CCN(c3ncccc3C(N)=O)CC2)c1 +Cc1ccc(-c2nnc(Cn3cc(Br)ccc3=O)o2)cc1 +CC(C(=O)Oc1cccc(C(N)=O)c1)c1cccs1 +COCCN1C(C)CN(C(=O)Cc2cccc(OCC#N)c2)CC1C +Cc1cc(N)ccc1NC(=O)C(C)n1cc(Cl)cn1 +NC(=O)C1CCC(NC(=O)c2ccc(-c3ccccc3)cc2)CC1 +CC1CCCCC1OCCN1CCOC(Cn2cccn2)C1 +O=C(CCn1cnc2ccccc21)N1CCCC(c2ccn[nH]2)C1 +Cc1cc(C)n(CCOC(=O)C2CC(=O)N(CC3CC3)C2)n1 +O=C(Cc1n[nH]c(=O)c2ccccc12)N1CC=C(c2ccccc2)CC1 +N#Cc1ccc(N2CCc3c(N)cccc3C2)nc1 +Cc1cc2c(cc1NC(=O)C1OCOc3ccccc31)OCCO2 +C#CCN(Cc1ccc(F)cc1)C(=O)CCNC(=O)C(C)(C)C +O=C(C1CC(=O)N(c2ccc(Cl)cc2)C1)N1CCCCC1 +Nc1ccc(OCC(=O)Nc2ccccc2F)c(F)c1 +Cc1ncc(N)cc1C(=O)N1CCCCC1C(N)=O +CCCC(C)NC(=O)C1CC(=O)N(c2ccc(F)c(Cl)c2)C1 +Cc1ccc(Nc2ncccc2S(N)(=O)=O)cc1Cl +CCCC(O)c1cc2c(c(C)c1C)NC(=O)C2(C)C +Cn1cc(CCNC(=O)N2CCC(CO)CC2)cn1 +CC(C)(C)CC(O)(Cn1ccnc1)c1cccnc1 +CNC(=O)NCC(=O)Nc1ccc(F)c(Br)c1 +CC(CCCO)NC(=O)NCc1cccc(NC(=O)N(C)C)c1 +Cc1cccc(C)c1NC(=O)NCCNC(=O)c1ccc(F)cc1 +NC(=O)Cn1cc(NC(=O)C2CC2c2cccc3ccccc23)cn1 +CCc1cc(=O)[nH]c(SCC(=O)Nc2cccc(O)c2)n1 +CCCN(Cc1ccc(C#N)cc1)C(=O)CNC(=O)NC +CCC(C)C(=O)N1CCCC(C(=O)NCC(OC)c2ccccc2)C1 +Cn1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1=O +CC(C)CN1CCOC(CNC(=O)c2cccnc2N2CCCC2)C1 +COC(C(=O)N1CCNC(=O)CC1)c1ccccc1 +Cc1cc(C(=O)NCC2CCN(C(=O)c3cccnc3)CC2)no1 +CCOc1ccc(Br)cc1C(O)C(C)C +O=C(Nc1cnn(-c2ccccc2F)c1)c1ccc(O)c(Cl)c1 +CCCc1c(C(=O)NCC(F)(F)F)[nH]c(C)c1C(=O)OC +COCCOC(=O)c1ccc(Cn2ccccc2=O)o1 +CNC(=O)c1ccc(S(=O)(=O)NCC2CCOC2)cc1 +CC(=O)NCC1CCN(C(=O)c2ccnc(-n3ccnc3)c2)CC1 +Cc1nn(CCC(C)C)c(C)c1S(=O)(=O)N1CCCCC1 +CCc1noc(C2CCCCN2C(=O)c2cc(C)oc2C)n1 +CC(c1nc2ccccc2s1)N(C)C(=O)NC1CCCCNC1=O +Cc1nc(C(=O)N(C)Cc2ccc(OC(F)F)cc2)cs1 +CNC(=O)COc1ccc(S(=O)(=O)N2CCOCC2)cc1C +CCC(C)NS(=O)(=O)c1cccc2c1CCNC2 +CCCc1[nH]nc(C(=O)N(C)CC(C)(C)C)c1N +CCOC(=O)Nc1nc(CC(=O)Nc2ccc(Cl)cc2)cs1 +N#Cc1ccccc1NC1C(=O)Nc2cc(Br)ccc21 +N#CC(Cc1ccc(F)cc1)C(=O)Nc1ccc(F)cc1 +CCOC(=O)CNC(=O)N1CCCC1c1cc(C(C)C)on1 +CCNC(=O)c1cc(NC2CCCCC2O)ccn1 +COc1ccc(NC(=O)c2cnccn2)c2cccnc12 +CCCNC(=O)CSc1nc2ccsc2c(=O)n1CC +CNc1ccc(C)cc1C(=O)NCC1CCCOC1 +Cc1cc(N)c(NC(=O)c2ccc3c(c2)OCO3)cc1C +Cc1noc(C)c1C(C)NC(=O)Nc1cccn(C)c1=O +CN(C)S(=O)(=O)c1cccc(-c2cc(=O)cc[nH]2)c1 +COc1ccnc(NC(=O)c2coc3ccccc23)c1 +COc1ccc(Cl)cc1CNC(=O)Nc1ccc(C(C)=O)cc1 +CCCCS(=O)(=O)NC(C)c1ccc2c(c1)OCO2 +Cc1nc(C(C)N(C)S(=O)(=O)Cc2ccc(F)cc2)c(C)s1 +O=C(Nc1n[nH]c2cc(Br)ccc12)c1ccccc1 +Nc1cc(=O)n(Cc2ccccc2)c(=O)n1Cc1ccccc1 +Cc1ccccc1CNC(=O)C(C)c1ccsc1 +CC(OC(=O)c1nccnc1N)C(=O)Nc1ccccc1 +Cc1cc(NC(=O)CNc2cc(S(C)(=O)=O)ccc2C)on1 +Cc1nnc(N2CCCC(CS(N)(=O)=O)C2)c(C#N)c1C +C=CCNC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +CC(C#N)CN(C)C(=O)c1ccc(S(C)(=O)=O)cc1 +CCOc1ccc(-c2cc(CC#N)c(C)o2)cc1OCC +O=C(Nc1ccnc2[nH]ncc12)c1ccccc1O +O=C(c1cn[nH]n1)N(Cc1ccncc1)CC1CCCO1 +Cc1ccccc1SCC(=O)N1CCC2(CC1)CN(C)C(=O)O2 +Cc1noc(CCCNC(=O)C(O)c2cc(Cl)cc(Cl)c2)n1 +Cc1ccccc1C(CC(C)C)NC(=O)N(C)Cc1ncnn1C +Cc1cc(C)cc(NC(=O)NC(CCCO)c2ccccc2)c1 +CC(=O)Nc1ccc(Br)cc1C(C)=O +CCCc1nnc(NC(=O)N(C)Cc2ccc(OC)cc2)s1 +Cc1ccc(C(=O)c2noc3cc(C#N)c(C#N)cc23)cc1 +CC(C)Oc1cncc(C(=O)C(C#N)c2ccc(F)cn2)c1 +CCC(=O)c1ccc(OCC(=O)NC(C)(C)C)cc1 +O=C1c2cc(Cl)ccc2C2OCc3ccccc3N12 +COc1ccc(Cn2nc(C)n(-c3cccc(Cl)c3)c2=O)cc1 +CC1CCCN(c2ncnc(Nc3ccccc3F)c2N)C1 +CC1CCCN(C(=O)NC2CCN(C(=O)c3cnccn3)CC2)CC1 +Cn1nc(C(=O)NC2CCCC2OCc2ccccc2)ccc1=O +O=C(CSc1ncn[nH]1)NCCOc1cccc(Cl)c1Cl +Cc1ccc(C(C)NC(=O)C2CC(=O)N(C(C)C)C2)cc1F +N#Cc1ccc(OCCNC(=O)Cc2ccc(F)cc2F)cc1 +CC(C)OCCCNC(=O)NCc1ccncc1 +CCN(CC)C(=O)COc1cccc(NC(=O)c2cnn(C)c2)c1 +CC(Nc1cnn(CC(=O)N2CCOCC2)c1)C1CCCC1 +Cc1ccccc1COC1CCN(C(=O)C(C)c2cccs2)CC1 +FC(F)(F)c1ccc(NCc2cccs2)cn1 +Cc1ccc(CCC(=O)NCc2ccoc2)c(C)c1 +Nc1cccc2c1N(C(=O)CCc1ccco1)CCC2 +Clc1ccc(-c2noc(C3CCCN(Cc4ccon4)C3)n2)cc1 +COc1cc(F)c(CN2CCN(c3ccccc3)C(=O)C2)c(F)c1 +CCc1nc2n(n1)CCCC2NC(=O)CCn1cnc2ccccc21 +CC(C)Cc1nnc2sc(NC(=O)C3CCCCC3)nn12 +CCn1nc(C)c(S(=O)(=O)Nc2ccc(NC(C)=O)cc2)c1C +CCNc1nnc(SCC(=O)Nc2c(C)cc(C)cc2C)s1 +CCCNC(=O)CCC(=O)c1ccc2c(c1)OCCO2 +Cc1cccc(Cl)c1NC(=O)NCCCN1CCOCC1 +O=C(c1c[nH]c2cccc(F)c12)N1CCCCCC1c1ccncc1 +COc1cccc(C(=O)NCCc2nc(C)cs2)c1 +CNC(=O)c1cc(NC(=O)NC(C)C)ccc1Cl +COC(=O)CN(C)C(=O)C1CCC(=O)N(CCc2ccccc2)C1 +CCOc1ccccc1Nc1nnc(SCc2ncnn2C)s1 +O=C(CNC(=O)C1Cc2ccc(Cl)cc2C(=O)O1)c1cccs1 +CCC(CO)NC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +COc1ccc(C(=O)Nc2cc3[nH]c(=O)[nH]c3cc2C)cc1OC +Cc1nnc(SC(C)c2nc3ccccc3n2C(F)F)s1 +COc1ccc2c(c1)CCC(CC1(O)C(=O)Nc3ccccc31)C2=O +CC(=O)Nc1cccc(C(=O)NCc2cccs2)c1 +CCCn1ncc(C(=O)N2CCN(C3CCCCC3O)CC2)c1C +Cc1cc(CN(C)Cc2ccccc2Br)no1 +CC(C)=CC1C(C(=O)N(CC(N)=O)C2CCCC2)C1(C)C +CCN(CC(C)C#N)C(=O)CNc1ccc(F)c(C(F)(F)F)c1 +CC(Nc1nccc(-c2cnn(C)c2)n1)c1ccccc1C(F)(F)F +Cc1ccc(CNC(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)s1 +COc1ccc(NC(=O)c2c(-c3ccc(F)cc3F)noc2C)cc1 +CNS(=O)(=O)c1ccc(C(=O)NCc2c(C)noc2C)o1 +O=C(CCN1CCOCC1)Nc1ccc(F)cc1 +CCOc1ccccc1C(=O)NCC(=O)Nc1cc(OC)ccc1F +Cn1c(=O)c2nc(-c3nnc4n3CCCCC4)c(N)nc2n(C)c1=O +Cc1sc2ncnc(NCC3CN(CC(C)C)CCO3)c2c1C +O=C(c1ccc(-n2ccnn2)cc1)N(CC(F)(F)F)C1CCCC1 +COCCc1nc2c(C#N)cc(-c3ccccc3)cn2n1 +COc1ccc(C)cc1C(=O)CCNc1cccc(C#N)c1 +Nc1c(Br)ccc2c1CC(c1cn[nH]c1)C2 +COc1cccc(OCC(=O)NCc2cnn3ccccc23)c1 +CC(C)C(=O)c1ccccc1NC(=O)Cc1ccc(OCC#N)cc1 +COc1cc(S(=O)(=O)NCCc2ccccc2)c(OC)cc1C +COc1ccc(CC(=O)Nc2nc3c(s2)CCCCC3)cc1OC +CCCC(=O)N1CCC(C(=O)Nc2cc(F)c(OC)c(F)c2)CC1 +CCCOc1cc(CO)cc2c1OC(c1ccccc1)C(=O)N2 +O=C(NCCNc1cnccn1)c1ccccc1Cl +COCC(=O)N1CCN(C(=O)c2cc(C)on2)CC1 +COC(C)C(=O)Nc1ccc2c(c1)CCN2C(=O)c1cccnc1 +CCc1ccc(C(C)NC(=O)CN2CCN(C(C)=O)CC2)cc1 +CCC1COCCN1S(=O)(=O)c1ccccc1NC +COCc1cc(N)nc(-c2cccc(Cl)c2Cl)n1 +N#Cc1ccc(Cn2c(CCO)nc3cccnc32)cc1 +CC(c1ccn(C(=O)Nc2ccccc2)n1)n1cncn1 +CCN(CCO)C(=O)Nc1cccc(C#Cc2ccccc2)c1 +CCOCC1CN(S(=O)(=O)c2ccccc2)Cc2nccn2C1 +C#CCN1CCC(C(=O)Nc2ccccc2OCC2CC2)CC1 +CC(c1ccccc1F)N(C)C(=O)c1cc2c([nH]c1=O)CCCC2 +CC(C)(C#N)C(=O)N1CCC(Cc2ccccc2)CC1 +CNC(=O)NCC(=O)Nc1cc(-c2ccccc2C)nn1C +COC1CC(NC(C)=O)C(OC(=O)c2ccccc2)C(CO)O1 +Cc1ccc(OS(=O)(=O)c2ccc(C#N)cc2)c(C)c1 +O=C(NCc1nnnn1-c1ccc(F)c(F)c1)c1cccs1 +CCc1cccc2c1N(C(=O)c1oc(C)nc1C)CC2 +CCC(=O)Nc1cccc(NC(=O)Cc2csc(C(C)C)n2)c1 +Cc1cnn(CCC(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)c1 +COC(CNC(=O)N(C)Cc1c(C)noc1C)c1ccccc1 +CC(Sc1nccn1C)C(=O)NC1CCCCC1C +CCc1cccc(N2CCC(NC(=O)c3ccco3)CC2)c1 +O=C1CCCN1c1ccc(Cl)c(C(=O)N2CCCC2C2CCC2)c1 +Oc1ccc(-c2nnc3c4cnn(-c5ccccc5)c4ncn23)cc1 +CCC(=O)N1CCCN(Cc2ccc(F)cc2C(F)(F)F)CC1 +N#Cc1nnn(Cc2ccccc2)c1COc1ccccc1 +N#CCCN(Cc1ccccn1)C(=O)c1cnc(-c2ccccc2)nc1 +COc1ccccc1NS(=O)(=O)c1ccc(C)c(NC(C)=O)c1 +Cc1cccc(C(=O)N2CCC(Cc3cccc(C(N)=O)c3)C2)n1 +CCCCn1cc(C(N)=O)c(=O)c2c(N)cccc21 +COc1ccccc1OCCC(=O)N1CCCCC1c1nccs1 +CC1CN(Cc2nnc(-c3cc4ccccn4n3)o2)CC(C)O1 +COc1ccc2c(=O)c(O)c(-c3ccccc3)oc2c1 +COc1c(F)cc(NC(=O)NCCC(=O)N2CCCC2)cc1F +COCCN1CCN(C(=O)c2ccc(-n3cnnc3)cc2)CC1=O +CCOc1cc(OCC)c(C(C)=O)c(OCC)c1 +COCCN(CC(=O)N(C)C)C(=O)c1ccc(C)nc1 +COC(=O)c1sccc1-n1cc(C(=O)C(C)n2cncn2)nn1 +O=C1CCN(C(=O)CCOc2ccc(Cl)c(Cl)c2)CCN1 +Cc1cccc(C(=O)NCC(=O)OCc2cccc(F)c2F)c1 +CCCn1c(=NC(C)=O)sc2cc3c(cc21)OCCO3 +O=C(NC1CCCOC1)c1cc(-c2cccs2)no1 +CCN(CC1COc2ccccc2O1)C(=O)CCc1ccco1 +CCCC1CN(Cc2c[nH]nc2-c2ccc3c(c2)OCCO3)CCO1 +Cc1ccnn1CCNC(=O)c1cccc(-n2cnnc2)c1 +COc1ccc(NC(=O)C2CCCO2)c(Cl)c1 +Cc1ccc(-c2cc(C(=O)NCc3ccc4c(c3)OCO4)on2)cc1 +CC(=O)N(Cc1nccn1Cc1ccccc1)C1CC1 +CCS(=O)(=O)Nc1ccc2c(c1)N(C)C(=O)C(C)(C)CO2 +COc1ccc(CC(=O)NCc2c(C)cc(C)nc2OC)c(OC)c1 +CCC(C)NC(=O)c1snc(-c2ccccc2F)c1N +CCS(=O)(=O)c1ccccc1C(=O)N1CCc2ccccc21 +Cc1nnc(C(C)N2CCC(c3ccccc3C)C2)o1 +COCCOC(=O)Cn1cc(CO)c2cc(C)ccc21 +Cc1ccc(NC(=O)c2oc3cccnc3c2N)cc1 +COc1cc(C)cc(C)c1-c1cc(C#N)c(=O)n(C)n1 +COc1ccc2nc(NC(=O)CCn3cc(C)cn3)sc2c1 +O=c1cc(-c2ccccc2C(F)(F)F)nc(C2CC2)[nH]1 +Brc1ccsc1CN1CCN(CC2OCCO2)CC1 +Nc1cccc(CC2Oc3ccccc3N(CC(O)CO)C2=O)c1 +O=C(c1cc(F)ccc1Br)N1CCOCC1C1CC1 +Cc1nnc(NC(=O)C(C)Oc2ccc3c(C)cc(=O)oc3c2)s1 +OCc1ccc(-c2nccn2Cc2nc(Cc3cccs3)no2)o1 +CCCCNC(=O)CCc1c(C)nc2nc(C)nn2c1C +COc1ccc(NC(=O)Cc2nc3ccccc3[nH]2)cc1 +CCC(O)c1c(C)nc2c(C)cc(Br)cn12 +COC(=O)C1CN(Cc2ccc(OC(C)C#N)cc2)CCO1 +O=C1COc2cc(NC(=O)NCCc3cccc(Cl)c3)ccc2N1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCN(CCO)CC1 +CCOc1ccc(NC(=O)c2ccc(=O)oc2)cc1CO +COc1cc(OC)c(CCC(=O)N(C)c2ccccc2)cc1N +COc1cc(C)c(S(=O)(=O)N(C)C(C)C)cc1OC +CCn1c(NCCn2cccn2)nc2sc3c(c2c1=O)CCCC3 +CNC(=O)C(C)N1CCC2(CCC1=O)CC(=O)c1cc(C)ccc1O2 +CN(C)c1ccc(-c2nccn2CCc2c[nH]cn2)cn1 +CN(C)C(=O)C1CCCN1c1ncnc2c1cnn2CCC#N +c1cnc(-n2cncn2)c(NCC2CCOCC2)c1 +CC1Oc2ccc(-c3cc(N)ncn3)cc2N(C)C1=O +CCOc1ccc(NC(=O)c2csc(-c3cnn(C)c3)n2)c(C)c1 +COc1ccc(NC(=O)C2CC(=O)N(C)C2)cc1OC +O=C(Cn1nnc2ccccc2c1=O)N=c1[nH]c2ccccc2s1 +O=C(Nc1ccccc1N1CCCC1=O)C1CC=CC1 +Cc1cc(CNS(=O)(=O)Cc2ccccc2Cl)c(C)o1 +O=C(c1ccsc1)N1CCc2nnc(-c3ccccn3)n2CC1 +Cc1ccc(NC(=O)c2nccc3ccc(N)cc23)cc1 +COc1ncccc1CNC(=O)c1cnc2n(c1=O)CCS2 +CC(=O)c1ccc(CNC(=O)c2cccc(N(C)C)c2)nc1C +CCOC(=O)Nc1ccc(NC(=O)c2ccc(F)c(COC)c2)cc1 +COc1ccc(CNC(=O)c2cc(C)c(C)s2)cc1OC +C#CCOc1ccccc1CNC(=O)NC(C)(CO)C1CC1 +CC(C)c1nc2ccccc2n1CC(=O)N1CCCC1 +Cn1cccc(NC(=O)Cn2ccc3ccc(Cl)cc32)c1=O +Cc1ccc(CNCCc2nccn2Cc2ccccc2)o1 +N#Cc1ccc(OCC(=O)Nc2ccncc2)cc1 +CC(C)NC(=O)COCc1cc(-c2ccc3c(c2)OCO3)on1 +CCN(C(=O)c1ccc2cc[nH]c2c1)C(C)C(C)C +CNC(=O)C(C)OC(=O)c1ccc(COc2ccc(F)cc2)o1 +Nc1ccc2oc(=O)n(Cc3cccc(Cl)c3)c2c1 +CCC(C)NC(=O)c1ccc(NC(=O)N(C)CC2CCCCO2)cc1 +Cc1ccc(C(=O)NC(C)C(=O)N2CCCCC2)cc1C +CC(OCc1ccccc1)C(=O)N(C)C(C)CC#N +Cc1ccc(C(=O)CSc2nnc(C3CC3)n2C2CC2)s1 +Cc1cc(OC(C)C)ccc1NC(=O)NCc1scnc1C +NS(=O)(=O)c1cccc(CNC(=O)Nc2nccs2)c1 +Cc1ccc(OS(=O)(=O)c2ccc(C(N)=O)cc2)c(C)c1 +Cc1cc(NCc2ccccc2OCC(=O)N2CCCC2)ccc1F +COc1ccccc1N1CCn2c(nc3cc(C(N)=O)ccc32)C1 +O=C(Cn1ncc2ccccc2c1=O)NCc1ccc2c(c1)OCO2 +CN(C)C(=O)c1ccc(Cl)c(NCC(=O)N2CCCCC2)c1 +NC(=O)c1ccc(NC(=O)c2ccc(Br)c(F)c2)cc1 +COc1ccccc1CNS(=O)(=O)c1ccc(CNC(C)=O)cc1 +Cc1ccc(F)c(-c2cc(N3CCOCC3)ncn2)c1 +Cc1ncsc1CCC(=O)NCc1ccc2nonc2c1 +O=c1ccc(CNc2ccc(Cl)cc2F)c[nH]1 +CCn1cc(NC(=O)NCC2(c3ccc(F)cc3)CCCC2)nn1 +O=c1[nH]c2ccccc2nc1Cn1cnc2ccc(Cl)cc2c1=O +Cc1cccc(C(N)=O)c1NCC(=O)N(C)CC(F)(F)F +Cn1cc(Nc2nc(-c3ccncc3)nc3ccccc23)cn1 +CCc1nnc2ccc(N(C)Cc3ccc(OC)cc3OC)nn12 +CCC(C)CN(C)C(=O)NC(C)C(=O)N1CCCCC1C +CC(=O)Nc1ccc(NC(=O)N2CCCCC2)cc1 +Cc1nn(C)c2[nH]c(=O)c(CCC(=O)Nc3ccncc3)c(C)c12 +CC1CN(C(=O)Cn2ccc(=O)c3sccc32)CC(C)O1 +CCOCCn1ccc2c(OCC(=O)NC)cccc2c1=O +O=C(CCN1CCCCC1=O)NCc1cc(F)ccc1C(F)(F)F +CCN(Cc1cccc(C)c1)C(=O)NCCCn1cccn1 +COCc1cccc(C(=O)N2CCCCC2CCO)c1 +CCOC(=O)C=C(c1cccs1)C(F)(F)F +COc1ccc(OCC2CCCN(c3nc(N)ncc3C)C2)cc1 +CCN(C(=O)CCC(C#N)c1ccncc1)c1ccccc1 +O=C(Nc1cccc(CO)c1)c1cc(Br)c[nH]1 +CCc1nc(C2CCCN2C(=O)C(C)OCCOC)no1 +COCCN1CCC2(CCN(c3ncccn3)CC2)C1=O +CCC(C)NC(=O)c1c(C)sc2ccn(CC(C)C)c(=O)c12 +CS(=O)(=O)N1CCC(CNC(=O)Cc2ccc(Cl)cc2)CC1 +Cc1cn2c(CN(C)C(=O)CCCn3cccc3)c(C)nc2s1 +CC(C)(C)C(=O)N1CCN(C(=O)c2ccco2)CC1 +CC(=O)N1CCN(C(=O)C2(c3ccc(Cl)cc3)CC2)CC1 +Cc1nc(CNC(=O)NC(C)c2ccc3c(c2)CCC(=O)N3)cs1 +CCOC(=O)c1cnc2sc3c(n2c1=O)CCCC3 +Cc1cc(C)n(-c2ccc(C(=O)NCc3cnn(C)c3)cc2F)n1 +N#Cc1cc(F)ccc1NC(=O)NCc1cn2cc(Cl)ccc2n1 +Cc1ncc(C(=O)NCCCC(C)(C)C2OCCO2)s1 +Cn1cc(C(=O)NCCC(O)c2ccccc2)c(C(C)(C)C)n1 +CCc1ccc(C(=O)Nc2cnc(N3CCCC3)nc2)cc1 +O=C1N(Cc2cccc(F)c2)CCC12CCN(Cc1nccs1)C2 +CCOc1cc(OC)ccc1C(N)C(=O)NCCO +CCCn1ncc(-c2cccc(OC)c2)c(CC#N)c1=O +CC(C)c1nc(-c2ccc(S(N)(=O)=O)cc2)n(-c2ccccc2)n1 +CCS(=O)(=O)c1ccc(C)cc1-c1cc(C(=O)OC(C)C)no1 +N#CCn1c(=O)nc(-c2ccccc2)c2ccccc21 +COC(=O)C1CCN(C(=O)CNC(=O)c2ccco2)CC1 +Cc1ccc(OCC(=O)Nc2ccc(Br)cc2)nc1 +CCCc1cc(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)n[nH]1 +CC(NC(=O)c1ccc(=O)n(C)c1)c1ccc(Cl)cc1 +Oc1ccc2c(c1)nc(C1CC1)n2-c1ccccc1F +O=C(NCCn1ncccc1=O)c1ccc(N2CCCC2)nn1 +CC(C)(C)C(=O)NCCCC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CCc1nnc(NC(=O)NCC(C)(C)c2ccccc2)s1 +Cn1ncc2c1CCc1sc(NC(=O)Cc3ccsc3)nc1-2 +COCCc1c(C)nn(-c2nc3ccccc3o2)c1O +CN(C)c1ncncc1NC(=O)c1cnc(C2CCCO2)s1 +O=c1cc(C2CCC2)ncn1Cc1ccc(-n2cccn2)cc1 +Cc1nc(CNC(=O)Cc2ccc(O)cc2Cl)c(C)s1 +N#Cc1cc(C(F)(F)F)ccc1Br +Cc1cnc(C(=O)NCC(c2ccccc2)c2ccccc2)cn1 +C=CCn1c(C(C)NC(=O)c2ccc(OC)cc2)nc2ccccc21 +CCOC(=O)C(C)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +Cc1ccc(CNC(=O)c2cccc(C(N)=O)c2)cc1F +Cc1ccc(C(=O)Nc2c3c(nn2C)CCC3)n1C +CS(=O)(=O)NC1CCN(S(=O)(=O)c2cn[nH]c2)CC1 +COc1cc(C)c(Cl)cc1CCCCn1cc(N)cn1 +Cc1ccc(N)c(S(=O)(=O)Nc2cn[nH]c2)c1C +CC(C)(Oc1ccc(Br)cc1)C(=O)n1ccnc1 +COc1ccc(CC(=O)NC(C#N)c2cccs2)cc1 +CC(C)(C)c1ccc(O)c(C(O)c2ccccn2)c1 +OCCN1CCN(c2ccc(-c3ccccc3)nn2)CC1 +COC(=O)Cc1c(C)nc(SCCO)[nH]c1=O +CC(=O)c1ccc(OC(=O)c2ccc(C)s2)cc1 +NC(=O)CSc1nnnn1-c1ccc2c(c1)OCO2 +COCCN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(C)c(F)c1 +CC(NCc1ccnc(OCC2CC2)c1)c1cccs1 +Cc1ccnc(CC(C)N(C)C(=O)c2cnn(Cc3ccccc3)c2)c1 +CCn1cc(NC(=O)C(C)n2cc3c(n2)c(C)nn3C)cn1 +Nc1ccccc1S(=O)(=O)Nc1cccc(F)c1 +CCN(CC)C(=O)c1c(Cl)cc(N(CC)CC)oc1=O +O=C(Cn1cnnn1)Nc1nc2ccccc2s1 +O=C(OCC(=O)c1ccc(Cl)cc1)C1=NC=CC1 +CCOC(=O)CCCc1ccc2c(c1)OCCO2 +Cc1cccc(NC(=O)c2cnc(N)c(Cl)c2)c1 +COCCNC(=O)Nc1ccc(CC(=O)N2CCCC2)cc1 +CC(C)CCOc1ccc(C(=O)N2CCN(C(=O)N(C)C)CC2)cc1 +COc1c(Br)cccc1CCNC(C)=O +Cc1ccc(C(=O)N2CCSc3ccc(N)cc32)o1 +CC(C)(C)Nc1nc(OCC#N)nc(N2CCOCC2)n1 +Cn1nccc1NC(=O)Cn1cc(-c2cccc3cccnc23)cn1 +Cc1ccc(NC(=O)C(C)Sc2ncnc3nc[nH]c23)c(C)c1 +CCc1ccc(C(NC(=O)COC)C(C)(C)C)o1 +O=C(C1Cc2ccccc2CN1C(=O)c1ccccc1)N1CCCC1 +CCOC(=O)N1CCC(NC(=O)c2ccc(F)cc2F)CC1 +COc1ccc(NCc2ccc(OC(C)C)c(OC)c2)cn1 +CCNC(=O)CN1CCN(C(=O)NC(C)CCC(C)C)CC1 +O=C(NCCNC(=O)C1CC=CCC1)c1ccc(F)cc1 +Cc1ccc(NC(=O)CNC(=O)c2ccc(F)cc2)cc1F +CCC(NC(=O)CNC(=O)c1cccc(F)c1)c1ccc(Cl)cc1 +CC1CC1CNC(=O)c1ccc(NC(=O)C2CC2)cc1 +Cc1ccc(Br)cc1NC(=O)N1CCCC1 +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)N1CCCC(C)CC1 +CCCN(CCc1ccccn1)C(=O)c1scnc1C1CC1 +Cc1cc(NC(=O)c2ccc3[nH]cnc3c2)sn1 +CC(C)c1c[nH]c(=O)c(C#N)c1-c1ccc2c(c1)OCCO2 +O=C(Oc1ccc2c(c1)CCC2)C1CCCN(c2ncccn2)C1 +O=C(c1cc2cccn2cn1)N1CCCc2ccccc21 +Cn1c(-c2c(C(C)(C)C)nn(CCO)c2N)nc2ccccc21 +O=C(NCCCn1ccnn1)Nc1cc(F)cc(C(F)(F)F)c1 +CCC(C)C(=O)NCC(=O)N1CCN(C(=O)OC)CC1 +Cc1sc(=O)n(CC(=O)Nc2ccc3ncccc3c2)c1C +COc1ccc(C(=O)N2CCc3sccc3C2)c(OC)c1 +N#Cc1cccc(C(=O)NCc2ccc(F)c(Cl)c2)c1 +COc1cc(C#N)ccc1OCCSc1nnc(C(C)(C)C)n1N +Cc1ccc(N)c2ccnc(C(=O)Nc3c(F)cccc3F)c12 +CC(C)CC1COCCN1C(=O)c1ccc(N2CCNC2=O)cc1 +OC1CCCN(c2nc3ccccc3nc2NC2CC2)C1 +CC(C)C(=O)N1CCC2(CCCN(c3nncs3)C2)C1 +O=C(NCc1cc(Cl)ccn1)Nc1ccc(NC(=O)C2CC2)cc1 +CNS(=O)(=O)c1cc(NC(=O)c2n[nH]c3ccccc23)ccc1C +O=C(Nc1cccc(O)c1)c1cccc2[nH]ccc12 +CC(C#N)CNC(=O)C1(c2cccc(F)c2)CCOCC1 +Cc1ccc(C(=O)N2CCN(CC(=O)N3CCCC(C)C3)CC2)s1 +CCOc1cc(S(=O)(=O)n2ccnc2CC)c(OCC)cc1C +CC(=O)N(Cc1noc(C)n1)C1CCN(CC(C#N)CCC#N)C1 +CC(C)N(C(=O)CCNC(=O)c1ccc(F)cc1F)C1CCC1 +Cc1ccccc1CC1Oc2ccc(N)cc2NC1=O +O=C(Nc1ccc2c(c1)C(O)=Nc1cccnc1O2)c1ccccc1 +Fc1cccc(NCc2nc3ccccc3s2)c1 +CC(C)c1ccc(Nc2ncccc2S(N)(=O)=O)cc1 +CCOCCCNC(=O)c1cnc(-c2ccco2)nc1N +NC(=O)C1CN(C(=O)Nc2ccc3c(c2)oc2ccccc23)CCO1 +O=C(CN1CCCCC1=O)Nc1ccc(-n2ccnc2)cc1 +CN(Cc1ccsc1)C(=O)c1ccccc1S(C)(=O)=O +CCN1C(=O)C(Cc2cccc(F)c2)Oc2ccc(N)cc21 +Cn1cc(C(=O)N(Cc2c(F)cccc2Cl)C2CC2)ccc1=O +CC(C)(C)n1c(=NC(=O)CCCNC(=O)C2CC2)[nH]c2ccccc21 +Cn1nnc2ccc(C(=O)N(CCC(N)=O)c3ccc(F)cc3)cc21 +O=C(OCc1cc(-c2ccc3c(c2)OCCO3)on1)c1ccno1 +Cc1ccccc1NCCC(=O)N1CCOC(c2ccc(F)cc2)C1 +CCc1ccc(CNC(=O)c2cnn(C(C)CC)c2C2CC2)s1 +CCCNC(=O)CNC(=O)N1CCC(CN2CCOCC2)CC1 +CCCCCNC(=O)C1CCN(C(=O)Nc2nccs2)CC1 +O=C1N=C(c2ccccn2)NC1Cc1ccccc1 +Cc1cc(F)ccc1NC(=O)N1CCC(NS(C)(=O)=O)CC1 +Cc1ccc(-n2c(SCC(N)=O)nnc2-c2ccoc2C)cc1 +Cc1ccc(OCC(=O)NCc2nc(C3CC3)no2)cc1C +Cc1nc(-c2cccs2)ccc1C(=O)N1CCN(CCO)CC1 +COc1ccc(C(C)=O)c(OC(=O)C2CC2c2ccccc2)c1 +CC=CCCNC(=O)c1cc(N2CCCC2=O)ccc1Cl +CCN(CC(C)C#N)C(=O)c1ccc(Cl)c(N)c1 +O=C1OCCN1CCN1CCN(Cc2nccn2C(F)F)CC1 +CC(=O)NCCNC(=O)NC(C)c1ccc(F)cc1 +Cc1cc(C)n(CCOC(=O)CCc2cc(Cl)cs2)n1 +CC1CC(C)CN(C(=O)CSc2nnc(Cc3ccccc3)o2)C1 +N#CC1(C(=O)OCc2nc(-c3ccc(F)cc3)no2)CCCC1 +CC(C)(C)c1noc(CCCC(=O)Oc2ccc3c(c2)OCO3)n1 +CCNC(=O)c1cccc(-c2cc(O)cc(C#N)c2)c1 +COCCN(Cc1ccc(F)cc1Cl)C(=O)c1cc[nH]n1 +CC(c1cc(F)ccc1F)N(C)C(=O)C1CCOCC1 +COc1ccc(NC(=O)c2ccc3[nH]c(C)nc3c2)cc1 +O=C(COc1cc(Cl)ccc1Cl)N1CCC(CO)C1 +O=C1Cc2cccc(C(=O)NCc3ccccc3F)c2N1 +Cc1nnc(NC(=O)CCc2nc(-c3ccccn3)no2)s1 +Cc1ccc(C)n1-c1sccc1C(=O)N1CCN(C(C)C)CC1 +CC(NC(=O)Nc1ccnn1C)C1CCOCC1 +Cc1cc(C(=O)C(C#N)c2ccccn2)cc(=O)[nH]1 +CCCc1nn2c(=O)cc(CN3CCc4ccccc43)nc2s1 +Cc1ccc2oc3c(c(=O)c2c1)C(c1ccccc1)N(CCCO)C3=O +Cc1cc(-c2nnc(NC(=O)C(C)Oc3ccccc3)o2)n(C)n1 +CC(=O)N1CCN(C(=O)c2ccc3c(c2)OCO3)CC1 +CCn1nc(C(C)C)cc1C(=O)OCC(=O)N1CCCCCC1 +Clc1cnc(NCC2(c3ccncc3)CC2)nc1 +C=CCSc1nnc(NC(=O)Cc2coc3ccc(F)cc23)s1 +Cc1cc(C(=O)NC2(CNC(=O)OC(C)(C)C)CCCC2)c(C)o1 +COc1ccc(C(=O)NCc2cn[nH]c2)cc1OC +COc1ccc(NC(=O)COC(=O)c2ccccn2)c(OC)c1 +OCC(O)CCc1ccc(OCc2ccc(F)cc2)cc1 +CC(=O)c1ccccc1NC(=O)c1ccn(-c2ccccc2Cl)n1 +COc1ccc(NC(=O)c2nnn(-c3nccs3)c2C)cc1Cl +COc1cccc(OCC(=O)Nc2ccccc2CC(N)=O)c1 +COc1ccccc1OCC(=O)NCC1CCCC(C)C1 +CC(C)OCC(O)CNc1cc(F)cc(F)c1F +CCCCOC(C)C(=O)N1Cc2ccccc2CC1C(N)=O +COc1ccc(C(=O)Nc2ccc(CCC(=O)NC(C)C)cc2)cc1 +Cc1cc(C(=O)N(CCC#N)Cc2ccco2)c2ccc(F)cc2n1 +CCCc1nc(C(=O)N(C)C(C)c2ccon2)cs1 +O=C(Cn1ncc(Cl)c(Cl)c1=O)Nc1cccc(F)c1 +Cc1cc(=O)n(CC(=O)NCC(C)C)c2c(C)cccc12 +COc1nc(C)nc(NCCc2ccc(F)cc2)c1N +CN1CC(C(=O)Nc2ccccc2-c2ccccc2)CC1=O +Cc1cc2c(=O)n(C)c(SCC(=O)c3cccs3)nc2s1 +Cc1cc(C)cc(OCCNC(=O)CN(C)C(N)=O)c1 +COc1ccc(CN(C)C(=O)COc2ccc(C)cc2)cc1F +CCCCNC(=O)Nc1cnn(Cc2ccccc2Cl)c1 +COCc1nc(COc2cccc(C)c2)sc1C#N +Cc1ccc(CNC(=O)NCC(=O)NC2CCCCC2C)cc1 +CN(CC1COc2ccccc2O1)c1nccn2cnnc12 +CCCCn1nnnc1COc1ccc(-c2nnco2)cc1 +Cc1cc(C)n(-c2ccc(NC(=O)C3CC=CC3)cc2F)n1 +CCc1ccc(NC(=O)C2=NC=C(C(C)O)C2)cc1 +N#Cc1ccc(NCc2cc(-c3ccccc3)no2)cc1 +CC(C)Oc1cncc(OC2CC2)c1C(=O)N(C)C +CCOCCCNC(=O)c1cc(=O)c2cc(F)cc(N)c2o1 +Cc1nn(C)c(C)c1CNC(=O)Cc1ccc(-n2cnnn2)cc1 +CCc1nnc2n1CC(NC(=O)c1ccc(N(C)C)nc1)CC2 +CCC1COC2(CCCN(C(=O)c3cnc4ccccc4c3)C2)C1 +CC(=O)Oc1cc(OC(C)=O)c2c3c(c(=O)oc2c1)CCC3 +CC(Cc1ccsc1)Nc1ccc(N)cc1C(N)=O +Cc1ccc(CCC(=O)Nc2nnc(C(C)C)s2)cc1 +COCCCn1c(=O)[nH]c2sc3c(c2c1=O)CCCC3 +Cc1ccc(NC(=O)CCNC(=O)C(C)(C)C)c(C)c1 +CCc1noc(CC)c1CNC(=O)NCc1ccc(F)cc1 +Cc1ccc(S(=O)(=O)NCCC(=O)NC2CC2)cc1C +Cc1ccc(N2CC(c3nc(-c4ccncc4)no3)CCC2=O)cc1C +CCN(CC)S(=O)(=O)NC(C)c1ccc(C)o1 +CC(C)C(NC(N)=O)C(=O)NCc1cccc(OC(F)F)c1 +O=C(Nc1ccn(Cc2ccccc2)n1)c1ccsc1 +CC(C)(C)NS(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +O=C(COc1ccccc1-c1noc(-c2ccccc2)n1)N1CCCC1 +CC(C)c1cccc(NC(=O)CCNS(=O)(=O)c2cccnc2)c1 +CC1Oc2ccc(Cc3c(O)n[nH]c3N)cc2NC1=O +Cc1ncsc1C1NCCc2ccc3c(c21)CCO3 +CCCCN(C)C(=O)Cn1c(=O)oc2cc(CO)ccc21 +Cn1c(=O)c2c(ncn2CC(=O)OCCc2cccnc2)n(C)c1=O +Cn1ncc2c(Oc3ccc(Cl)cc3Cl)ncnc21 +COCCNC(=O)N1CCC(c2ccccc2)CC1 +COc1cc(C)c(C(=O)NCC(C)N(C)c2ccccc2)cc1OC +Cc1sc(=O)n(CC(=O)Nc2ccc3oc(C4CC4)nc3c2)c1C +CCN1C(=O)C(CC(=O)N2CCC(C)CC2)Sc2ncccc21 +CCCNC(=O)Cc1c(C)nc(-c2ccccn2)[nH]c1=O +CC(=O)Nc1cc(F)c(F)cc1NCC(=O)Nc1ccc(C)cc1 +CNC(=O)C(C)NC(=O)c1cc(F)c(NC)c(F)c1 +Cc1ccc(C(=O)OCC(=O)NCc2ccccc2C)cc1O +CCC(C)NC(=O)c1nc(-c2ccc(N3CCCC3)cc2)no1 +COc1ccc2c(c1)OC1(CCN(C(C)=O)CC1)CNC2=O +CCN(CC)C(C)(C(=O)OC)c1ccc(F)cc1 +CNC(=O)c1ccc(N)c(OCCN2CCOCC2)c1 +O=C(NCC1COC2(CCCC2)O1)c1cccs1 +CCn1cc(C(=O)Nc2nnc(C(C)(C)C)s2)cn1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2ccc(Cl)cc2)cc1 +CNC(=O)C(C)NC(=O)Cc1ccc(F)c(F)c1 +Fc1ccc2c(c1F)C(c1ccc3ncccc3c1)NCC2 +O=C(NCc1cccs1)c1cccnc1OCC(F)F +CCOC(=O)CCC(=O)c1ccc2[nH]c(=O)oc2c1 +COc1cccc(OC)c1C(=O)c1cccc(C2OCCO2)c1 +Nc1c(-c2nc(-c3ccccc3)no2)nnn1-c1ccc(F)cc1 +Cn1cc(NC(=O)CCC2Cc3ccccc3NC2=O)cn1 +Cn1ncc(Cl)c1C(=O)Nc1nnc(C(F)(F)F)s1 +O=c1cc(CN2Cc3ccccc3C(O)C2)[nH]c(=O)[nH]1 +COc1ccc(N(C)C(=O)CCSc2ccccn2)cn1 +O=C(c1nn(-c2ccccc2)c(=O)c2ncccc12)N1CCCC1 +O=C(Nc1ccc(C(F)(F)F)cc1)N1CC2COCC(C2)C1 +Cc1ccc2[nH]cc(-c3nc(C4CCOC4)no3)c(=O)c2c1 +CCn1cnnc1CCNC(=O)c1cc(=O)n(C)c(=O)n1C +CCOC(=O)CCc1c(C)c2cc(Cl)c(O)cc2oc1=O +Cn1ncc2c(N3CCC(C(=O)N4CCCCC4)CC3)ncnc21 +N#CCCN(Cc1cccnc1)C(=O)c1ccc[nH]1 +Cc1ccc(-c2ncco2)cc1NC(=O)CCCNC(=O)C1CC1 +O=C(NCCCOc1ccccc1F)c1ccc(O)nc1 +COc1ccc(F)c(NC(=O)NC(C)c2cnn(C)c2)c1 +COc1cccc2c(=O)c3c(O)cc(OCC(N)=O)cc3oc12 +Nc1c(-c2ccccc2)noc1C(=O)N1CCCCCC1 +CNC(=O)c1cccc(COc2ccccc2CC(N)=O)c1 +COC(=O)CCNS(=O)(=O)c1c(Cl)cccc1Cl +COc1ccc(Cl)cc1S(=O)(=O)N(CCO)CCO +COc1ccc(CCNC(=O)N2CCC3(CC2)OCCCO3)cc1 +COCCOc1ccc(NC(=O)c2cc(Cl)ccn2)cc1F +Cc1ccccc1Cn1cccc(S(=O)(=O)N2CCCC2)c1=O +COc1ccc(C(=O)NC(C)c2cccc(Br)c2)nn1 +C=CCN(CC=C)C(=O)c1cnn(-c2ccc(F)cc2)n1 +CCc1ccc(NC(=O)c2nc(-c3ccncc3)no2)cc1 +CCOC(=O)C1CCN(CC(=O)c2c[nH]c3ccc(C)cc23)CC1 +Cc1ccc(OCCNC(=O)c2ccc(CNC(N)=O)cc2)c(C)c1 +O=C(NCC(Cc1cccc(F)c1)N1CCCC1=O)C1CCC1 +Cc1ccc(-n2c(=O)[nH]c3c(C(N)=O)nc(C(C)C)nc32)cc1 +CCCC(=O)N1CCCC(C(=O)N(C)C(C)c2cccnc2)C1 +CNC(=O)c1ccc(Cn2nnc(-c3ccccc3)n2)cc1 +CCCOc1ccccc1NC(=O)CCc1c(C)nc(C)[nH]c1=O +Cc1cc(CNC(=O)N=c2[nH]cc(C)s2)on1 +CCn1nnc2cc(C(=O)N3CCC(C(N)=O)c4ccccc43)ccc21 +CCNC(=O)NCC(=O)N1CCN(c2ccccc2)CC1 +CC(NC(=O)Cc1ccc2c(c1)CCC2)C(=O)NCc1ccco1 +CCCNC(=O)CN1CCN(c2cccc(OC)c2)CC1 +CCS(=O)(=O)c1nc(C)c(C)n1C1CCCCC1 +CCC(C)NC(=O)CCNC(=O)NCc1ccccc1 +CN(Cc1nc2ccccc2s1)C(=O)c1cscn1 +Cc1cc(C(=O)N2CCN(Cc3scnc3C)CC2)on1 +COc1ccc(Br)c(C(=O)N(C)CC(=O)N(C)C)c1 +Clc1ccc2c(c1)CN(Cc1nnnn1C1CC1)CC2 +Cn1c(C(C#N)C(=O)CCn2ccc3ccccc32)nc2ccccc21 +CCC(C)C(C)NS(=O)(=O)c1cc(N)ccc1C +O=C(Nc1c(F)cc(F)cc1F)N1CCCC1CN1CCOCC1 +CC(C)=CC1C(C(=O)Nc2cccc(C(=O)NCC(N)=O)c2)C1(C)C +CCCS(=O)(=O)NC(C#N)c1cccc(OCC)c1 +Cc1nn(C)c(C)c1NC(=O)CN1CCc2cc(F)ccc2C1 +CCC(=O)N(Cc1csc(COc2ccccc2)n1)C1CC1 +FC(F)C(F)(F)CCN1CCCC(c2nccn2CC2CC2)C1 +CSc1nnc(N2CCN(c3ccccc3)CC2)s1 +CN(C)C(=O)CSc1nnc2c3ccccc3nc(C(C)(C)C)n12 +CCC(=O)NC1CCCN(C(=O)Nc2ccc3c(c2)oc(=O)n3C)C1 +COCCN(Cc1ccccn1)C(=O)Nc1ccc(OC)nc1 +COc1ccsc1C(=O)N1Cc2ccccc2CC1C(N)=O +N#Cc1c(NC(=O)COc2ccc3c(c2)OCO3)sc2c1CCC2 +CC(O)c1nc2cc3c(cc2n1-c1ccccc1)OCCO3 +COC(=O)c1sccc1NC(=O)c1cc(C)n(-c2ccccc2)n1 +Cc1cnccc1C1NCCc2c1ccc(C)c2Cl +CC1CC(C(=O)N2CCCC(C(=O)NC3CCCCC3)C2)CCO1 +CCOCCCNC(=O)c1ccc2c(c1)N(S(C)(=O)=O)CC2 +O=C(NC1CC1)c1ccc(-c2nc3ccccc3[nH]2)cc1 +Cn1cc(S(=O)(=O)N2CCCC2)cc1C(=O)OC1CCCCC1 +COCC(=O)NCCNC(=O)c1ccc(NC(C)=O)cc1 +COC(=O)CSc1nc2nc(C)c(-c3cccs3)c(N)n2n1 +Cc1cc(C)nc(C2CCN(C(=O)c3ccn(C)n3)C2)n1 +COC(=O)C1CCN(C(=O)CCc2ccccc2)CC1 +Cc1cc(-c2cc(C#N)nn2CC(N)=O)ccc1F +COC(=O)C(C#N)CC(=O)c1ccc2c(c1)CCCC2 +Cc1cc(C(=O)Nc2nnc(-c3cccc(F)c3)o2)nn1C +CNC(=O)CN1c2ccccc2C(=O)N(C)C1c1cc2ccccc2o1 +CC(NS(=O)(=O)c1cccnc1)c1cc2ccccc2o1 +Cc1nc(-c2ccccc2Br)ncc1N +CC(C)Cc1noc(Cn2nc3ccccn3c2=O)n1 +Cc1ccc(N2CC3CN(C(=O)c4ccco4)CC3C2)nn1 +NC(=O)C1CCN(C(=O)Cc2cc(-c3ccccc3F)on2)CC1 +COc1ccc(NC(=O)c2cc(S(N)(=O)=O)c(C)o2)cc1C +Cc1cccc(C)c1NC(=O)C1CC1c1ccco1 +N#Cc1cc(Br)ccc1N1CCCC(CCC(N)=O)C1 +CCOc1ccc(-c2ccc(CO)c(=O)n2C(C)CC)cc1 +N#CCCSc1nccn1Cc1ccccc1Cl +CCOC(=O)COc1cccc(NC(=O)c2ccccc2)c1 +CCN(CC)C(=O)CCC(=O)Nc1cccc2cnccc12 +COc1ccccc1-c1c2c(nc3[nH]nc(N)c13)CCC2 +O=C1CC2C(CCN2Cc2ccncc2)N1c1cncnc1 +Cc1ccc(Cn2cc(NC(=O)Cc3ccc(F)cc3)cn2)cc1 +Cc1nn(C)cc1C(=O)Nc1ccn(-c2ncccc2Cl)n1 +CC(C)NC(=O)CNc1cncc(Br)c1 +O=C1OCCC1Oc1ccc(Cl)c2cccnc12 +CCc1cnc(C(C)NC(=O)Nc2cc(C)cc3cccnc23)s1 +N#Cc1cccc(N2CC(CO)C(CN3CCOCC3)C2)n1 +COc1ccc(S(=O)(=O)Nc2cccc3[nH]ncc23)c(C)c1 +CN(C)c1nccc(C2CCCCN2Cc2ccccn2)n1 +Cc1cnc2n(c1=O)CC(C(=O)N(CCO)c1ccccc1)CS2 +O=C1NC2(CCN(C(=O)c3ccco3)CC2)Nc2ccccc21 +CCn1c(C)cc(C(=O)CSc2nnc(C)o2)c1C +CC(C)c1ncc(Br)c(-c2ccn(C)c2)n1 +CC(Cn1nnc2ccccc21)NC(=O)c1cscn1 +COCCCNC(=O)NC12CC3CC(CC(C3)C1)C2 +CCC(C)N(Cc1ccccc1)C(=O)C1CC(=O)N(C)C1 +O=C(C1CC=CC1)N1CC=C(c2cccs2)CC1 +Cc1cc(C(=O)CN2CCCS2(=O)=O)c(C)n1-c1nccs1 +CCOc1ccc(S(=O)(=O)Nc2ccc3c(c2)oc(=O)n3C)cc1 +Cn1cc(C(=O)N2CCOCC2)cc(NC(=O)c2cccnc2)c1=O +O=C(NCc1ccc(OCc2ccccn2)cc1)c1ccccn1 +CN1C(=O)CN(C(=O)C2(C)CCCC2)c2ccccc21 +Cc1cc(CN(C)C(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)no1 +O=C(NCCNC(=O)c1cc2cccn2cn1)c1cccnc1 +COc1cccc(NC(=O)Nc2nnc(-c3ccco3)o2)c1OC +CCCSc1nnc(N2CCC(C)CC2)n1C1CC1 +CC(=O)Nc1cc(S(=O)(=O)Nc2ccnn2C(C)C)ccc1F +O=C(Cn1ncc2ccccc2c1=O)OCc1nc2ccccc2[nH]1 +CC(C)Cc1nnc(NC(=O)c2ccc3c(ccn3C)c2)s1 +CC1CC(C)CN(C(=O)c2cc(OCC(=O)N3CCCC3)n(C)n2)C1 +CCc1onc(C)c1NC(=O)NCC(C)Nc1ccccc1 +CCc1ccc(-c2cc(=O)[nH]c(C(C)C)n2)cc1N +CC(NC(=O)CCCc1c[nH]c2ccccc12)c1ccncc1 +CCOC(=O)CSc1nnc(C(F)(F)F)n1N +CC(=O)Nc1cccc(CNC(=O)C(C)c2ccsc2)c1 +COC(=O)c1ccc(OCC(=O)N2CCOCC2)c(Cl)c1 +COc1ccccc1N1CCN(CCNC(=O)C2CCCC2)CC1 +CCc1csc(C2CCCN(c3cnccn3)C2)n1 +CCOc1ccc(F)c(C(=O)NCC2CCOC2C(C)C)c1F +N#Cc1ccccc1C(=O)N1CCC(Oc2cccc(F)c2)CC1 +Cc1ccsc1-c1nc2c3c(ncn2n1)CCC3 +CCOC(=O)c1cc(Cl)c(NC(=O)c2ccco2)cc1OC +CCn1nccc1C(=O)N1CCN(C(C)C)CC1 +N#Cc1ccc(NC(=O)c2cc(OCc3ccccc3)no2)cc1 +Cc1cc(C(=O)Nc2nc3c(C)cccc3s2)on1 +CCCOC1CCCN(C(=O)Cc2ccc(-n3cnnn3)cc2)CC1 +CCOc1ncccc1C(=O)N(C)C1CCCCC1 +Cc1ccc(CN(C)Cc2nc3ccsc3c(=O)[nH]2)s1 +Cc1ccc(NC(=O)C(C)n2cncn2)c(OCc2ccccc2)c1 +C#CCOCC1CCCN(C(=O)c2cccc(OC)c2OC)C1 +COc1cccc(C(=O)NC(c2ccccn2)c2ccccc2OC)c1 +COC(=O)CCN(C)S(=O)(=O)c1ccc(C)cc1N +Cc1c(NC(=O)Nc2ccccc2)cccc1C(N)=O +COc1ccc(C(=O)NCCCC(N)=O)c(O)c1 +Cc1nc(NC(=O)c2cccnc2Oc2cccnc2)sc1C +Cc1cc(NCc2ncc3c(n2)CCC3)nc(-c2ccccc2O)n1 +C=CCn1c(C2CC(=O)N(c3cccc(C)c3)C2)nc2ccccc21 +COc1ccc(C(=O)N2CCC(O)CC2)c2ccccc12 +CC(C)c1nc2ccc(S(=O)(=O)N3CCOCC3)cc2[nH]c1=O +CCc1nnc(CN(CC)C(=O)COc2ccc(F)cc2F)o1 +Cc1cc(-c2c(CCCO)sc3nccn23)ccc1F +NS(=O)(=O)c1ccc(-n2ccnc2-c2ccc(CO)o2)cc1 +CCOC(=O)Cn1nc(-c2ccc(F)cc2)oc1=O +CCCN(CCC)C(=O)CCc1c(C)nc2nc(N)nn2c1C +CC(C1CC1)N(C)C(=O)Cn1cc(Br)c(=O)[nH]c1=O +COC(=O)c1cccc(NC(=O)c2cnc3n(c2=O)CCS3)c1 +O=C1CC(C(=O)N2CCc3ccc(F)cc32)CCN1 +CCCn1c(=O)[nH]c(=O)c2cc(C(=O)N3CCOC(CC)C3)cnc21 +COCC(=O)N(Cc1ccco1)Cc1cccs1 +CCOC(=O)c1nc(N2CCc3ccccc3C2)c2c(C)noc2n1 +CC1CCC(NC(=O)COc2cccc(Cl)c2)CC1 +Cc1cnc(NC(=O)NC2CCSc3c(F)cccc32)s1 +Cc1c(C(=O)N(C)CC2CCCCO2)sc2ccc(F)cc12 +Cc1ccc(OCCCNC(=O)Nc2cnccc2C)cc1 +O=C(NC1CC(O)C(CO)C1)c1ccc(-n2cccc2)cc1 +Cc1cc(C)n(-c2ccc(NC(=O)N3CCCC(O)C3)cc2F)n1 +Cc1ccccc1-n1cnnc1SC1CCOC1=O +CCOC(=O)Oc1ccc2c(c1)C(C)=CC(C)(C)N2 +CCn1cnnc1CNS(=O)(=O)c1ccc(F)cc1 +O=C(CNC(=O)c1csnn1)Nc1cccc(F)c1 +CCn1c(=O)n(CC(=O)NC(C)(C#N)C(C)C)c2ccccc21 +CN(C)c1nc(N)nc(CSc2nccn2C)n1 +COc1ccc(F)cc1NC(=O)NCC1CC(=O)Nc2ccccc21 +CCCCN(C)S(=O)(=O)NCc1cn2ccccc2n1 +COc1c(C)cc(Br)c(C)c1C(N)=O +CC(NC(=O)c1ccccc1)C(=O)Nc1cccc2cccnc12 +CC(C)C(=O)Nc1ccc(C(=O)Nc2nc[nH]n2)cc1 +O=C(COC(=O)c1cc[nH]n1)NC1(c2ccccc2)CCC1 +CC(=O)c1nc2cc(O)ccc2n1Cc1ccccc1 +O=C(CSc1ccc2c(c1)OCCO2)C1=NC=CC1 +COCc1ccc(CN2CCN(c3nc(C)ns3)CC2)o1 +O=C(Cn1cnc2ccccc2c1=O)OCC(=O)N1CCCC1 +O=C1NCCN(C(=O)c2cn3ccsc3n2)C1c1cccc(F)c1 +Nc1cccc2c1OCCN2C(=O)c1ccncc1 +Cc1nc(CNc2ccc3cc[nH]c3n2)nc2c1CCCC2 +CC(C)(O)CSc1nnnn1-c1ccc(Br)cc1 +CCCN(CCO)C(=O)Nc1cnn(-c2ccccc2F)c1 +CN(Cc1nccn1C(F)F)C(=O)C1Cc2cc(F)ccc2O1 +CC(c1ccccn1)N(C)C(=O)Nc1ccc2c(c1)NC(=O)CS2 +C#CCNc1cc(Cl)ccc1OCCOCC +O=C(NCc1cccs1)C1CCN(c2cnccn2)CC1 +Cc1ccnc(NC(=O)c2cnc(CC(C)C)nc2N)c1 +C=CCSc1ccccc1NC(=O)c1ccc2c(c1)OCCO2 +O=S(=O)(Cc1nc(-c2cccs2)no1)c1nc2ccccc2[nH]1 +O=C(CCc1ccccc1)Nn1cnc2ccccc21 +COc1cccc(C(=O)CSc2ncnc3ccccc23)c1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)NCc2ccccc2)c1 +CCC(C)(C)NC(=O)C1CC(=O)N(Cc2ccco2)C1 +COc1ccc(-c2nnc(SCc3c(C)noc3C)o2)cc1 +CNC(=O)c1ccc(CN(C)C(=O)c2cn[nH]n2)cc1 +COCc1ccc(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)o1 +O=C(NCCc1ccccn1)C1CC1c1ccc(Br)cc1 +NC(=O)COC(=O)Cn1cc(Br)ccc1=O +COc1c(O)ccc2c1C(c1n[nH]c3ccccc13)NCC2 +CCCN(CCC)C(=O)Cn1c(CO)nc2cc(C)c(C)cc21 +Cc1ccc(C(C)NC(=O)c2ccc(CCC(C)(C)O)cc2)cn1 +Nc1cc(F)c(N(Cc2ccco2)C2CC2)c(F)c1 +CC(=O)Oc1ccccc1C(=O)Nc1cccnc1 +COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C1CC1 +Cc1ccc(-n2nc(C(=O)N(C)C)nc2-c2ccccc2)cc1 +CCc1nc(C)sc1CNC(=O)C(O)c1ccc(Cl)cc1 +Cc1ccc(CCNCc2ccccc2C#N)cc1 +Cc1cc(C(=O)NCC(=O)Nc2cn[nH]c2)c(C)o1 +COCC(NC(=O)c1ccc(-n2ccnn2)cc1)c1ccco1 +Fc1cc(Cl)cnc1NCCc1nc(-c2ccco2)n[nH]1 +C=CCn1c(SCc2cc(=O)c(O)co2)nnc1C1CC1 +O=C1CC(c2cccnc2)c2c(nc3ccccn3c2=O)O1 +Cc1nonc1NC(=O)OCCN1CCOC1=O +O=S(=O)(NCc1ccncc1)c1ccc(OC(F)(F)F)cc1 +O=C(Nc1cc(F)c(F)c(F)c1)c1cccc(N2CCOC2=O)c1 +CC1=NC(=O)C(c2noc(CCC(=O)Nc3ccccc3C)n2)C=C1 +Cc1csc(N(C)C(=O)c2c(C)c(C)nn(C)c2=O)n1 +CCCC1CN(C(=O)c2ccc(OCc3cscn3)cc2)CCO1 +CC(c1cccs1)N(C)C(=O)CC1OCCc2ccccc21 +CCC1CCCCN1C(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +O=C1NCCN1c1ccc(NC(=O)C2(Cc3ccccc3)CCC2)cc1 +CCCNC(=O)COc1cccc(-c2nnco2)c1 +COc1ccc(C(=O)Nc2ccc(C(F)(F)F)oc2=O)cc1 +O=C(NCCNC(=O)c1ccn2ccsc12)c1ccccc1 +CC(=O)c1ccc(NC(=O)c2cc(C#N)cn2C)cc1C +CC(Cc1ccco1)NC(=O)Cn1c(=O)oc2ccccc21 +CSc1nc2n(n1)C(CC(=O)Nc1ccc3c(c1)OCO3)C(=O)N2 +Cc1n[nH]c(-c2ccc(C(=O)NC(C)Cc3ccsc3)cc2)n1 +Clc1ccc2c(c1)nc(C1CC1)n2Cc1ccco1 +CC1CCc2c(sc3ncn(CC(=O)N(C)C)c(=O)c23)C1 +COC(=O)c1sc(NC(=O)C2CC2(Cl)Cl)nc1C1CC1 +COCC1CCCN(C(=O)C2c3ccccc3Oc3ccccc32)C1 +COCc1cccc(NCc2c(C)nn(-c3ccccc3)c2C)c1 +N#CC1(C(=O)NCCOc2ccc(Cl)cc2)CCCC1 +O=C(c1ccncc1)N1CCCC1c1cccc(Cc2ccccc2)n1 +CCSc1nnc(NC(=O)Cc2c(F)cccc2Cl)s1 +Cc1cc(C)n(-c2ccc(C(=O)NC(C)C(N)=O)cn2)n1 +Cc1n[nH]c(C)c1CNC(=O)c1c[nH]c2cccc(F)c12 +O=c1c2ccccc2ncn1Nc1ncc(C(F)(F)F)cc1Cl +CC1CN(c2ccc(NC(=O)CCc3nccs3)cn2)CC(C)O1 +CC1CN(C(C)C(=O)Nc2ccccc2)c2cc(N)ccc2O1 +COc1cc(C(=O)Nc2ccc3c(c2)CCC3)ccc1OC(F)F +Cc1ccc2ncc(C(=O)OCc3ccccc3F)n2c1 +COc1ccc(C(=O)Nc2nnc(C)s2)nn1 +CCOc1ccc(NC(=O)CN2CC(C)Oc3ccc(N)cc32)cc1 +Cc1cccc(CCC(=O)NC(C)c2c(C)noc2C)c1 +Cc1cccc(NC(=O)c2ccc(S(=O)(=O)N(C)C)o2)c1 +CCCCN1CC(C(=O)Nc2ccc(C#N)cc2)CC1=O +O=C(Cc1csc(SCC(=O)c2cccs2)n1)NC1CC1 +COC1COC2(CCCN(S(=O)(=O)c3cn(C)cn3)C2)C1 +C=CCN(C1CCCC1)S(=O)(=O)c1ccc(=O)[nH]c1 +Cc1cc2c(Nc3ccncc3)nc(-c3cccnc3)nc2s1 +COC1COC2C1OCC2n1nnnc1C(C)C +CCCNC(=O)c1cc(C)n2nc(-c3ccccn3)cc2n1 +O=C(Nc1ccc(F)cc1F)N1CCC(N2CCOC2=O)CC1 +COc1ccccc1C(C)N(C)C(=O)c1ccnc(OC2CCC2)c1 +O=C(NCCCN1CCCCCC1=O)C1COc2ccccc2O1 +CCc1ccc(CCOC(=O)c2ncn(-c3ccccc3)n2)cc1 +COc1cc(N2CCC3(CC2)CC(N2CCOCC2)C3)ncn1 +CC(C)C(=O)NCCNC(=O)c1cc2cc(Cl)ccc2[nH]1 +Cc1nc(C)c(C2NCCc3c(F)cc(Cl)cc32)s1 +COc1cccc(CSc2nncn3c2cc2occc23)c1 +N#CCCNC(=O)CSc1nccc(C(F)(F)F)n1 +COC(=O)c1[nH]c2cccc(OC)c2c1NC(C)=O +Cc1noc(C2CCCN(C(=O)c3n[nH]c4c3CCC4)C2)n1 +Cc1cc(=O)c(OCC(=O)NCCc2c[nH]c3ccccc23)co1 +Cc1cn(C(C)C(=O)N(C)C)nc1-c1ccccc1 +COc1ccc(F)cc1NC(=O)c1ccc(OC)c(OC)c1 +Nc1nc(SCCCOCC(F)(F)F)n[nH]1 +COc1cc(S(=O)(=O)N2CCC(C)CC2)ccc1Cl +COCC(=O)N1CCCN(c2ccc(=O)n(-c3ccccc3)n2)CC1 +CC(CNC(=O)c1cnc(-c2ccccc2)nc1)c1cccs1 +CCC(C)NC(=O)NCCNC(=O)c1ccc(C(F)(F)F)cc1 +Cc1ccc(C#N)cc1S(=O)(=O)N(CCCO)CC(C)(C)C +Cc1ccc(CN2CCOCS2(=O)=O)c(C)c1 +CCC(=O)Nc1nnc(C=Cc2ccccc2)s1 +CC(NC(=O)c1ccccc1SCC(N)=O)C1CCCCC1 +Cc1ccc(C)c(OCC(=O)Nc2cccc(C(=O)NC(C)C)c2)c1 +COc1ccc(CC(=O)N2CCCn3ncnc32)c(OC)c1 +COc1cccc(C(=O)N(Cc2cccc(F)c2)C2CC2)c1 +Cc1nc(C2CCCN(C(=O)Cc3ccc4c(c3)OCCO4)C2)no1 +CCn1nnc(NC(=O)c2ccc3ccccc3c2)n1 +CC(=O)Nc1ccc(Nc2nc(C3CC3)nc3c(C)nn(C)c23)cc1 +CC(C)COc1nc(C(C)C)nc(NC2CCCC2)c1N +COc1ccc2ncc(C(=O)N3CCOCC3)c(Cl)c2c1 +CC(C(=O)N(C)Cc1ccccc1)n1nc(-n2cccn2)ccc1=O +CC(C)(C)NC(=O)CNC(=O)c1ccc2c(c1)CCC(=O)N2 +CCC1=C(C(=O)OC)C(c2ccc(OC)c(OC)c2)n2ncnc2N1 +CCNS(=O)(=O)c1ccc2c(c1)nc(C)n2CC +Fc1ccc(Cn2cc(-n3cccc3)cn2)c(F)c1 +CC(C)CC(C(=O)N(C)CC1CCC1)N1CCCCC1=O +CNC(=O)C1CCN(C(=O)Nc2cc(C#N)ccc2OC(C)C)CC1 +CCNC(=O)c1ccc(NC(=O)C2CC=CCC2)c(C)c1 +O=C(Nc1cccc(F)c1)Nc1ccn(Cc2ccncc2)n1 +COc1cccc(CNC(=O)c2ccn3ccsc23)c1 +COCC(=O)NC(C(=O)NCc1ccccc1C)C(C)C +O=C(CNC(=O)c1ccc(OCC(F)F)nc1)Nc1ccccc1 +Cc1ccc(C(C)NC(=O)c2ccc(S(N)(=O)=O)o2)cc1F +CCC(C)C(NC(=O)C(C)c1cccs1)C(N)=O +CCN(CC)S(=O)(=O)c1cccc(S(C)(=O)=O)c1 +Cn1cnnc1S(=O)(=O)Cc1csc(-c2ccsc2)n1 +CNC(=O)CN1CCN(c2ccc(OC)cc2)C1=O +CNc1nc(-c2sc(C)nc2C(C)(C)C)cs1 +Cn1cc(S(=O)(=O)N2CCCC2)cc1C(=O)N1CCCCCC1 +O=C(Nc1cccc(NC(=O)c2ccoc2)c1)c1ccncc1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1sc(C)nc1C +Cc1nnc(-c2cccc(-c3ccc(S(C)(=O)=O)cc3)c2)o1 +COc1ccc(C)cc1NC(=O)C12CCC(C1)C(C)(C)C2=O +CC(=O)Nc1nc(C(=O)N(C)Cc2ccoc2C)cs1 +Cc1nc(C)c(C(=O)NC(CO)c2ccc(Cl)c(F)c2)s1 +O=C1CCN(C(=O)Cc2ccc3c(c2)NC(=O)CO3)CC1 +Nc1cccc(C(=O)CNc2ccccc2C(F)(F)F)c1 +C#Cc1cccc(NC(=O)COc2cc(C)ccc2C)c1 +CC(=O)C(C)CSc1nc(-c2ccccn2)n[nH]1 +C#Cc1cccc(NC(=O)N2CCN(Cc3cccs3)CC2)c1 +CC(C)(C)OC(=O)NCC1CCCN(C(=O)c2cscn2)C1 +COc1cccc(CC(=O)Nc2nnc(-c3ccccc3)o2)c1 +Cc1nc2ccccc2n1CC(=O)NC(C(N)=O)c1ccccc1 +Cc1cc(C#N)nn1-c1ccc(Br)cc1 +O=C(Nc1ccc(CN2CCOCC2)cn1)C1CC1(Cl)Cl +CC(NC(=O)Nc1cc(F)cc(F)c1)c1ccncc1 +O=C(Nc1cc(N2CCCS2(=O)=O)ccc1O)C1CCC1 +CC(C)(C)c1ccc(C(=O)Nc2cccnc2)cc1 +CCCNC(=O)CNc1cc(C(=O)OC)c(F)cc1F +Cn1c(CN2CCN(c3ccc(F)cc3)CC2)cc(=O)n(C)c1=O +C=C(C)c1ccccc1NC(=O)Cn1cnc2ccccc2c1=O +Cc1cccnc1CNC(=O)Nc1nc2ccccn2n1 +CCc1ccccc1NC(=O)N1CCN(C)C2(CCNC(=O)CC2)C1 +O=C1NCCN(C(=O)Cc2ccccc2Cl)C1c1ccccc1 +COc1ccc(CN(C)CC(F)F)c(OC(F)F)c1 +CNC(=O)c1ccccc1OCc1nc(-c2ccccc2)no1 +N#Cc1c(N)nsc1Nc1ccccc1Cl +CCn1ncc(Br)c1C(=O)Nc1ccc(Cl)cc1 +CCCCN(C)C(=O)Nc1ccc(-n2cncn2)nc1 +CC(Cn1cncn1)NS(=O)(=O)c1ccc(Cl)cc1 +CSc1ccc(C(O)CNC(=O)NC2CCCCCC2)cc1 +CC(Sc1nnc(N2CCCC2)s1)C(=O)OC(C)(C)C +O=C(c1ccc2ccccc2n1)N1CCN(S(=O)(=O)C2CC2)CC1 +Cc1nc(C)c(C(=O)Nc2ccc(-n3ccnc3)cc2)s1 +O=C(NCc1ccc(Cn2cccn2)cc1)NCc1ccco1 +CC(=O)N1CCc2cc(NC(=O)Cc3cn(C)c4ccccc34)ccc21 +CCCC1CN(C(=O)COc2ccc(CC(N)=O)cc2)CCO1 +COc1ccc(CNC(=O)c2sc(C)cc2OC)cn1 +Cc1n[nH]c(SCC(=O)N2CCCc3ccccc32)n1 +CC(c1cccs1)N(C)C(=O)NCCCn1cncn1 +CCc1nc(CC(=O)Nc2ccc(CC(=O)NC)cc2)cs1 +Cc1ccc(NCC(O)c2cc(F)ccc2F)cc1 +CNS(=O)(=O)CC(=O)NC(C)C1CCCC(C)C1 +Cc1cccc(C)c1NC(=O)NC(C)c1ccc2c(c1)OCO2 +NC(=O)c1ccsc1NC(=O)CSc1nc(N)cc(N)n1 +O=C(Cc1cccs1)Nc1ccc2c(c1)OCCO2 +COC(=O)CSc1nc2c(c(=O)[nH]c(=O)n2C)n1CCC(C)C +COc1cc2c(cc1OC)CN(C(=O)c1cccc(C)c1)CC2 +Fc1ccc(-c2nc3c4c(ncn3n2)CCC4)cc1 +CC(C)C(NC(=O)OCc1ccccc1)S(=O)(=O)c1ccccc1 +CCc1ccccc1OC1CN(C(=O)c2c[nH]nc2-c2ccccc2)C1 +CNC(=O)CN1C(=O)COc2ccc(CO)cc21 +CC(NC(=O)c1cccn(CC(=O)N(C)C)c1=O)c1ccccn1 +COC(=O)c1ccc(Oc2ncnc3sccc23)cc1 +N#Cc1ccc(-c2ccc(F)c(F)c2)nc1NC1CC1 +CCc1ccc(C(=O)CCc2nc(C)cs2)cc1 +CC(C)NC(=O)Nc1cc(OCc2ccccc2)ncn1 +CCNC(=O)CCCC(O)c1ccc2c(c1)CCCC2 +CCOc1ccc(NC(=O)C2CCCN2C(C)=O)cc1 +Cc1nnc2ccc(C(=O)N(C)CC3CCCCC3)cn12 +CCC(NC(=O)CNC(=O)NC)c1nc2ccccc2[nH]1 +COc1ccc(F)cc1NC(=O)CCc1nc(-c2ccsc2)no1 +CN(C)C(=O)CN(C)C(=O)C(C)(C)c1ccccc1 +CCC(NC(=O)CN1C(=O)CCc2ccccc21)c1cccs1 +CCOc1ccc(N2C(=O)CCCC2C(=O)OC)cc1 +Cc1cc(CN(C)C(=O)c2ccc(C(=O)N(C)C)cc2)no1 +NC(=O)Nc1ccc2oc(=O)c3ccccc3c2c1 +CCN1CCOC(CCNC(=O)c2cc3cc(F)ccc3[nH]2)C1 +Cc1cc(C(=O)NC(C)C)ccc1NC(=O)c1sccc1C1CC1 +Nc1cc(COc2c(Cl)cccc2Cl)nn1CCO +Cc1nc2ccccc2c(=O)n1NC(=O)C1CC1C +CCc1noc(CSc2nnc(COc3ccc(C)cc3)o2)n1 +O=C(NCC(F)(F)F)c1cnn(Cc2ccccc2)c1 +O=C(NCc1cc2ccccc2[nH]1)c1ccc(-n2ccnn2)cc1 +CN(C)C(=O)c1ccc(CNC(=O)c2ccc(=O)n(C)c2)cc1 +O=C(Nc1ccc(F)c(F)c1)c1n[nH]c2ccccc12 +O=C(Nc1c(F)cccc1-n1cccn1)c1cc(-c2ccccn2)no1 +Cc1ccn(CCC(=O)NCC2COc3ccccc3O2)n1 +O=C(NCc1ccc2c(c1)CCCO2)c1cccc(Cn2cncn2)c1 +CNC(=O)Cn1nnc(CO)c1-c1ccc(OC)cc1 +CN(C)C(=O)CCNC(=O)Nc1ccccc1Br +Cn1cc(CCNC(=O)c2cccs2)c2cccnc21 +NC(=O)C1CCN(C(=O)Cc2ccc(OC(F)(F)F)cc2)C1 +CCOC(=O)c1ccc(NC(=O)NCc2ccco2)cc1 +N#Cc1ccc(S(=O)(=O)NCCOc2ccccc2)cc1 +CNC(=O)c1cccc(CCNS(=O)(=O)N2CCCCCC2)c1 +CC(Sc1nnc(C2CC2)n1C1CC1)c1cc(F)ccc1F +COCCCNC(=O)c1cc(-c2ccccc2)on1 +O=C1NC2(CCC2)NC1c1cc(Br)ccc1F +COc1nc2c(cc1C(=O)NCC(O)c1cccs1)CCC2 +O=C(NCC1CCCO1)Nc1ccc(Oc2cccc(F)c2)nc1 +Cc1c(C)n(Cc2ccco2)c2ncnc(N3CCCCC3)c12 +O=C(c1ccccc1)N1CCC2(CC(=O)N(c3ccc(F)cc3)C2)C1 +COc1ccc(C(=O)OCC(=O)N(C)c2ccccc2)c(OC)c1 +Cn1c(C(=O)OCC(=O)NCC2CCCO2)cc2sccc21 +CC(C)NC(=O)c1ccc(NC(=O)N(C)C(C)c2ccco2)cc1 +O=S(=O)(NCc1cccs1)Oc1ccccc1O +Fc1ccc(CCNc2ncnc3[nH]cnc23)cc1Br +Cc1nc(CC(=O)N(C)CC(=O)N2CCOCC2)cs1 +CCOc1ccccc1C(=O)NCC1(C(N)=O)CCOCC1 +O=c1oc2cccnc2n1Cc1cc(-c2ccccc2)on1 +CC(=O)NC(CC(=O)NCc1ccc2c(c1)OCO2)c1cccs1 +O=C(NCCCNC(=O)c1cccs1)c1cnc2[nH]ccc2c1 +c1c(CN2CCOCC2)nnn1CC1CCCO1 +Cn1cc(CNC(=O)Nc2cccc(C(F)F)c2)cn1 +Cc1ccc2ncc(C(=O)OC(C)C(F)(F)F)n2c1 +Cn1cnc2c1C(C(=O)NCCC#N)N(C(=O)c1ccccc1)CC2 +CC(C)OCc1ccc(CNC(=O)c2cccc(C(N)=O)c2)cc1 +N#Cc1ccc(N2CCCC2CO)cc1C(F)(F)F +CCN(Cc1ccccn1)C(=O)c1cccc(OC)c1F +CN(CCCNC(=O)Nc1nnc(C2CC2)s1)c1ccccc1F +COCCCNC(=O)c1cc2oc3ccccc3c2n1C +CCC(OC1CCCCC1)C(=O)NCc1cccc(-c2nc[nH]n2)c1 +CN(C)C(=O)c1nn(-c2ccc(F)cc2)c(=O)c2ccccc12 +Cn1cc(CCC(=O)NCCc2nccs2)c2ccccc21 +CC(=O)c1[nH]c(C)c(C(=O)N(C)Cc2sccc2C)c1C +Cc1ccc(C(=O)NC(C(=O)N(C)C(C)C)C(C)C)cc1 +COC(C)C(=O)Nc1ccccc1N1CCCC1=O +O=C(NCc1cn(-c2ccccc2)nn1)c1ccc(-n2cncn2)cc1 +CC(C)N(CC(N)=O)C(=O)Cc1coc(-c2ccccc2)n1 +C=C(C)CN(CC)C(=O)c1cn(C)c2ccc(C)cc2c1=O +CN(C)c1ncc2c(n1)sc1c(=O)n(N)cnc12 +CCOc1ccccc1CNC(=O)Nc1cccc(COC)c1 +Nc1cnn(CC(=O)Nc2cc(Br)ccc2F)c1 +O=C1OCCN1c1ccc(Cl)c(C(F)(F)F)c1 +CCN(C)C(=O)c1ccccc1SCC=C(C)C +O=S(=O)(NCc1ccccn1)c1ccc(F)cc1F +CC(C)c1ccc(C#N)c(=O)n1Cc1ccc(F)cc1 +Nc1nncn1C(=O)c1cccc(OCc2ccccc2)c1 +CC(C)NC(=O)C1CCN(c2nc3ccccc3n2C)CC1 +Cc1ccccc1NC(=O)CN1CCN(c2ccccc2)CC1 +Cc1cc(S(=O)(=O)NCC(O)c2ccsc2)ccc1F +CC(OCC(F)(F)F)C(=O)Nc1ccc(SC(F)F)cc1 +CN(C)C(=O)c1cccc(OCc2cccc(C(N)=O)c2)c1 +Cn1ccnc1CN1CCCN(C(=O)CC2C=CCC2)CC1 +CN(CC(=O)NC1(C(N)=O)CCCCC1)C(=O)c1ccccc1 +O=C(NC1CC1)c1ccc(NCc2ccc(F)c(F)c2)cc1 +Nc1cc(Cl)ccc1NC(=O)CCn1cc(Cl)cn1 +CC(C)C(=O)Nc1ccc(OCC(=O)N2CCCCCC2)cc1 +COC(=O)CN(C(=O)COc1ccc(C)cc1)C(C)C +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)Nc1nc(C2CC2)cs1 +O=C(CN1CCCCCC1=O)Nc1nc(C2CC2)cs1 +CN(Cc1nc2ccccc2s1)C(=O)c1ccc2c(c1)OCO2 +CCn1cc(S(=O)(=O)N2CC3CCC2C3)c(N)n1 +CC(C)c1nc2cc(O)ccc2n1Cc1cccc(N)c1 +COc1ccc(S(=O)(=O)n2cc(Br)cn2)cc1OC +CCOC(=O)N1CCN(C(=O)c2ccc(C#CC(C)(C)O)cc2)CC1 +C(Sc1nnnn1C1CC1)c1nc(C2CC2)no1 +Cc1cc(C)c(NC(=O)CNC(=O)c2ccc3ccccc3n2)c(C)c1 +Nc1ccc2ncn(-c3ccc4cn[nH]c4c3)c(=O)c2c1 +Cc1cccc(CC(=O)Nc2sccc2C(N)=O)c1 +Cc1nn(C)c(C)c1NCc1ccc(Br)cc1F +Cc1n[nH]c(SCC(=O)N2CCN(c3ccccc3F)CC2)n1 +COc1ccc2[nH]c(-c3cncn3C(C)CN3CCOCC3)cc2c1 +Cc1ncc2c(SCC(=O)Nc3cc(F)cc(F)c3)ncnc2n1 +CCn1cc(NS(=O)(=O)c2ccc(N3CCCC3=O)cc2C)cn1 +N#Cc1ccnc(-c2cc(NCc3cccnc3)nc3[nH]ccc23)c1 +COc1cc(CNc2cccc(N(C)C)c2)cc(Cl)c1O +Cc1cc(C)cc(Cn2nc(C)c(C)c(C#N)c2=O)c1 +COc1cccc2c1OCC(Cc1cccc(CNC(C)=O)c1)C2 +Cc1ccc(NC(=O)CCCc2nc(-c3ccco3)no2)cc1 +CCOc1ccccc1C(=O)NCCCC(=O)N1CCC(C)CC1 +CCOC(=O)C(NC(C)=O)C(O)c1ccc(Cl)cc1Cl +CC(C(=O)NCc1ccc(F)cc1)N1CCc2cc(F)ccc2C1 +Cc1ccc(-c2nnc(CNC(=O)Cc3ccccc3Cl)o2)s1 +O=S(=O)(NCc1cccc(Br)c1)c1cccnc1 +Cc1ccc(S(=O)(=O)N(CCO)C(C)C)s1 +CCN(CCC#N)C(=O)CNc1c(C)cccc1C(C)C +COCC(=O)Nc1cccc(NCC(=O)Nc2cccc(F)c2)c1 +CC1CN(C(=O)Nc2cnc(C3CC3)nc2)CC(c2ccsc2)O1 +OC1C(=Cc2cccnc2)CCC1=Cc1ccccn1 +CCc1ccc(OCCNCc2cncnc2)cc1 +COC(=O)CCC1CCCN(C(=O)OCc2ccccc2)C1 +CCOc1cc(C2NC(=O)C3CCCCN32)ccc1OCC(C)C +CCC1Oc2cc(Cl)c(N)c(Cl)c2N(C)C1=O +Fc1ccccc1-c1nnc(SCCc2ccncc2)n1C1CC1 +CC(=O)N(C)Cc1ccccc1NC(=O)C(C)OCc1ccccc1 +C=CCC1(CO)CCCN(c2ncc(F)c(N3CCOCC3)n2)C1 +COc1ccc(C)cc1C(O)CCCC(=O)NC(C)C +CCc1ccc(-c2csc(-c3nonc3N)n2)cc1 +Cc1cc(CN(C)C(=O)CCCOc2ccccc2C)no1 +CC(C)Oc1cccc(CNS(=O)(=O)c2ccc(F)cc2)c1 +Cc1ccc2nc(C)c(C(=O)C(C#N)c3ccccn3)cc2c1 +N#Cc1cccc(N2CCCC(CO)(Cc3ccc(F)cc3F)C2)n1 +CCOc1ccccc1C(=O)NCCNC(=O)c1ccccc1O +COC(=O)C1=C(C)C(C(=O)C(C)Oc2ccc(C#N)cc2)=NC1C +COc1ccc(-c2csc(CCNc3nc(=O)[nH]nc3C)n2)cc1 +CC(=O)Nc1cc(NC(=O)c2ccccn2)ccc1Cl +CCC1CCC(NC(=O)CNS(=O)(=O)c2cccs2)CC1 +O=C(NCCC(=O)N1CCCC1)Nc1cccc(Br)c1 +Cc1csc(C2CCN(C(=O)c3ccc4[nH]cnc4c3)CC2)n1 +CCC1CCCCN1C(=O)c1ccc(C)c(NC(C)=O)c1 +COc1ccccc1C(O)c1ccc2c(c1)CN(C(C)=O)C2 +COC(=O)C1CCN(C(=O)CSc2nc(C)cc(C)c2C#N)CC1 +CCCn1ncc2cc(C(=O)NC3CCCCC3)c(N)nc21 +Cc1cc(C)n2nc(NC(=O)NC(C)CC(=O)OC(C)(C)C)nc2n1 +CNC(=O)c1ccc(CNc2ccc(F)cc2OC(F)F)cc1 +O=C(c1c[nH]nc1-c1cccc(Cl)c1)N1CCOCC1 +NC(=O)Nc1cccc(C(=O)Nc2ccc(Cl)c(Cl)c2)c1 +O=C(NC1CCCCC1)c1csc(-c2cccnc2)n1 +CCN(Cc1c(F)cccc1Cl)CC(C)C#N +COc1cc(CN2CC(C)OCC2C)cc2c1OCCO2 +CCCn1nc(C(=O)Nc2cc(F)ccc2C)ccc1=O +CN1CC(C(=O)Nc2cccc(Br)c2)CC1=O +COc1ccc(CC(=O)Nc2ccccc2C)cc1 +COCCC1(C(=O)NCc2ncn(C)n2)CCC1 +O=C(NC1CCCc2nc(-c3ccccc3)ncc21)c1ccccc1O +COC(=O)CNC(=O)c1sc(-n2cccc2)nc1C +O=C(c1cscn1)N1CCn2cnc(COCC3CC3)c2C1 +Cc1ccc2oc(C(=O)N3CCCC3)cc(=O)c2c1 +Cc1ccccc1CNC(=O)c1nnc2ccc(-c3ccccc3)nn12 +COc1c(CNc2ccc(OCC(F)(F)F)nc2)c(C)nn1C +O=C(NCc1ccccn1)c1ccc(Cn2cccn2)o1 +CC1c2cc3c(cc2CCN1C(=O)c1cccc(F)c1)OCCCO3 +Cc1cccc(NC(=O)CC2Oc3ccccc3NC2=O)c1 +CCCNC(=O)C1CCN(C(=O)C2COc3ccc(F)cc3C2)CC1 +Cc1oc(-c2cccs2)nc1CNc1cc(C(N)=O)c(F)cc1F +COc1ccc(OCC(=O)Nc2cccc(OC(C)=O)c2)cc1 +Cc1cc(CN2CCN(C(=O)COc3ccc(F)cc3)CC2)on1 +COc1ccc(OC)c(Cc2nc(-c3ccc(N)cc3)cs2)c1 +CN(Cc1cc(Cl)cc(Cl)c1)C(=O)c1cc[nH]n1 +CN(C)C(=O)c1ccccc1NCc1cc(=O)n2ccccc2n1 +CC(=O)c1ccc(OCC(=O)Nc2nc(C)no2)cc1 +COc1ccccc1C(=O)N(CC1=CC2=CC=NC2C=C1)C1CC1 +COc1cccc(C(=O)Nc2ccc(-n3cnnn3)c(C)c2)c1F +CC(OCC1CC1)C(=O)Nc1c2c(nn1-c1ccccc1)CCC2 +CN(C(=O)c1cccnc1)C(C#N)c1ccncc1 +Cc1nn(C)c(=O)c(C(=O)Nc2ccc3cnn(C(C)C)c3c2)c1C +Cn1cnc(CNC(=O)C(C)(C)CC2CCOCC2)n1 +Nc1c(-c2nc3ccccc3[nH]2)c(-c2ccccc2)nn1CCO +CCC(CC)NC(=O)C(C)Oc1ccc2ccc(=O)oc2c1 +CN(C)C(=O)Cn1cc(Br)ccc1=O +Cc1ccc(S(=O)(=O)c2nnn(CCCO)c2N)cc1 +O=S(=O)(c1ccccc1Cl)N(CCO)CCO +Cc1ccc(-n2nnnc2CNC(=O)Nc2cccc(Cl)c2)cc1 +Cn1c(=O)c2c(Nc3cc(F)ccc3F)ccnc2n(C)c1=O +COc1ccc(OC)c(NC(=O)C(C)Oc2ccccc2OC)c1 +Cc1nc(-c2cccc(F)c2)nc(N2CCC(=O)CC2)c1C +CC(C)(C)c1nc(CN2CCN(C(=O)c3cccc(F)c3)CC2)no1 +COc1ccc(C)cc1NC(=O)C1CCN(C(=O)C2CC2)CC1 +COc1ccc(Nc2nc(C)c(C(C)=O)s2)cc1 +CC(C)c1ccccc1NC(=O)c1cnc2cc[nH]c2c1 +Cn1nccc1C(=O)N1CC(S(=O)(=O)N2CCc3ccccc32)C1 +Cn1ncc2c(=O)n(CC(=O)OCC3CCCCO3)cnc21 +CCOc1ccc(CC(=O)Nc2cccc(N)c2C)cc1 +COc1cc(C)c(C)cc1C(O)CNC(=O)c1cccc(C)c1 +COC(=O)Nc1cccc(NCc2nsc(N(C)C)n2)c1 +Cn1cnnc1CNC(=O)c1ccccc1Nc1ccccc1 +COc1cc(Nc2ncc(Br)cn2)cc(OC)c1OC +O=c1[nH]n(C2CCCC2)c2c1C(C1CCCCC1)CC(O)=N2 +COc1ccc(S(=O)(=O)Oc2cccc(-c3nnco3)c2)cc1 +O=c1c(Cl)c(Cl)cnn1Cc1cn2ccsc2n1 +O=C(Nc1ccc2c(c1)OCCCO2)c1ccccc1-n1cnnn1 +CCCc1nnc(NC(=O)N2CCCCC2c2nc[nH]n2)s1 +Cn1cc(C(=O)Nc2ccc(CC#N)cc2)c2ccccc21 +NC(=O)C1CCCCN1C(=O)c1ccc(F)cc1 +COC(=O)c1ccc(F)c(NCC(=O)N2CCCC(C)C2)c1 +CCN1CC(C(=O)Nc2ccc(C)cc2OCC2CCCO2)CC1=O +CCc1ccc(NS(=O)(=O)c2ccc(CO)cc2)cc1 +CC(=O)Nc1ccccc1OCc1c(F)cccc1Cl +COc1cc(NC(=O)c2cccs2)ccc1NC(=O)c1ccco1 +CCN(CC)c1ncnc(Nc2cccc(C(C)=O)c2)c1N +Cc1noc(C(C)NC(=O)Nc2cccc(NC(=O)C(C)(C)C)c2)n1 +CCc1nnnn1Cc1nnc(C2CC2)n1C1CC1 +NC(=O)c1n[nH]c2ccc(NCc3csc(-c4ccco4)n3)cc12 +Cc1cc(F)ccc1S(=O)(=O)Nc1ccc(-c2nc[nH]n2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)CCc1ccccc1 +Cc1cccc(C(=O)NCCC(=O)N2CCCCC2C)c1 +O=C(NC1CCc2ccccc21)c1ccc(F)cc1 +CC(C)CC(=O)Nc1cccc(S(=O)(=O)N2CCCCCC2)c1 +N#CCCN(Cc1ccccn1)C(=O)COc1ccccc1C#N +O=C(CCOc1ccccc1)N1CCCCC1CCO +CC(C)n1nccc1NC(=O)NCC1(C)CCCC1 +COCCCCNC(=O)CN1CCOc2ccc(Cl)cc21 +CCc1nnc(NC(=O)c2cc(C3CC3)nc3ccccc23)s1 +Cc1nnc(SCCC(N)=O)n1C1CCCCC1 +COc1ccc(OCC(=O)Nc2nnn(C)n2)cc1 +CCC(O)CN1CCN(C(=O)CCc2nc(C(C)C)no2)CC1 +COc1ccc2c(c1)nc(C(C)O)n2-c1ccc(C#N)cn1 +Cc1nn(C)c(C)c1CC(=O)Nc1cc(F)ccc1F +N#Cc1ccc(OC2CCN(C(=O)Cc3cccs3)CC2)nc1 +Cc1cc(-n2nc(C)nc2-c2ccc(C#CC(C)(C)O)o2)ccn1 +Cc1ccnc(NC(=O)c2ccccc2N2CCOCC2)c1 +COc1nn(C)cc1C(=O)NCC#CCOc1ccc(F)cc1F +Nc1ncnn1C(=O)c1cn(-c2ccccc2)nc1-c1ccccc1 +CCc1cc(-c2nc(CC3CCCO3)no2)n(C)n1 +Cc1cc2cc3c(cc2nc1SCC(N)=O)OCO3 +COC(=O)CSc1nc2ccsc2c(=O)n1Cc1ccccc1 +C=CCOC(=O)c1cc(Cl)c2c(c1)OCCO2 +Cc1cc(C)nc(C2CCN(C(=O)Cc3csc(C)n3)C2)n1 +Cc1ccc(C(C)(C)NC(=O)C2CCCN2C(N)=O)cc1 +Cc1cc(NC(=O)NCc2ccncc2)ccc1OCC(F)(F)F +O=C(Nc1ccc(CC(=O)N2CCOCC2)cc1)C1CCCCC1 +Cc1cc(-c2ccc3c(c2)OCCO3)c(C#N)c(=O)n1C(C)C +CCN(C(=O)Cc1cccc(OCC#N)c1)c1cccnc1 +Cn1ncc2c1C(COCC1CC1)CN(C(=O)c1ccccc1)C2 +COC(=O)CC1C(=O)NCCN1Cc1ccc(C(F)(F)F)cc1 +CC(C)CC1COCCN1C(=O)c1ccc2c(c1)OCCO2 +CCC(C)C(=O)CSc1nnc(-c2ccoc2C)o1 +CC(c1ccc(F)cc1F)N1CCN(C(=O)c2cn[nH]n2)CC1 +Cc1cc(C)n(C2CN(c3nc(-c4ccncc4)nc4c3CCC4)C2)n1 +Cc1nc2cc(NC(=O)c3c(C)nn4cccnc34)ccc2o1 +CC(C)(C(=O)N1CCOC(C(N)=O)C1)c1ccccc1Cl +Cc1ccc(C(C)NC(=O)NCC(=O)N(C)C)cc1F +CS(=O)(=O)N1CCC2C(COC2CNc2ncccn2)C1 +COc1nc2c(cc1C(=O)NCc1noc(-c3ccco3)n1)CCC2 +CCC1CCC(NC(=O)Cn2cc(C(F)(F)F)ccc2=O)CC1 +CC(C)CNc1nc(Oc2ccc(=O)n(C)n2)nc(N(C)C)n1 +OC(CCN1CCOCC1)c1ccc2c(c1)OCO2 +O=C(NCCC(=O)N1CCCC1c1ccccc1)c1ccco1 +CC(C)c1ncc(CNc2cnn(C(C)(C)C)c2)s1 +COc1ccccc1C(C#N)CC(=O)N1CCc2ccccc21 +Cc1ccc(CCC(=O)N2CCC(C(N)=O)C2)c(C)c1 +O=C(COCc1ccccc1Cl)NCC(=O)Nc1cn[nH]c1 +CC(=O)NCCC1=NC(COc2ccc(Cl)cc2)=NC(=O)C1 +O=C(NCc1nc(-c2cccc(Cl)c2)no1)C1CCCO1 +CN(Cc1ccccc1Cl)C(=O)C1CC=CCC1 +O=C(NC1CCN(c2ccccc2)C1)C1COc2ccc(F)cc2C1 +O=C(NCC1CCCO1)C1CN(C(=O)c2c[nH]c3ccccc23)C1 +COc1ccccc1NC(=O)c1sc2nc(C)cc(C)c2c1N +Cc1oc(C(=O)N(C(C)C)C2CCCC2)cc1S(N)(=O)=O +C#CCNC(=O)NCc1cccc(NC(=O)Cn2cccn2)c1 +Cc1cc(NC(=O)NCc2cc(C(C)C)no2)ccc1-n1cnnn1 +CC(NC(=O)c1cn(CC(=O)N(C)C)nn1)c1ccccc1 +CCn1nc(C(=O)NCC(C)O)c(=O)c2ccccc21 +Cc1nc2cc(NC(=O)CCc3nc4ccccc4[nH]3)ccc2o1 +CC(C)Cn1cc(C(=O)N(C)c2nccs2)c2ccccc21 +CCCC(=O)NC1CCN(S(=O)(=O)CC)CC1 +N#Cc1ccccc1C(N)c1nnc(-c2ccccc2)o1 +Cc1nc2cc(C(=O)NC(C)CCc3ccccc3)ccc2n(C)c1=O +Oc1cccc(Br)c1Br +C=CCOC(C)C(=O)Nc1ccc(NC(=O)CC)cc1 +CC(C)(C)OC(=O)N1CCC2CCC(=O)CC2CC1 +CC(C)(C)Oc1ccc(-c2cc(=O)n3nccc3[nH]2)cc1 +CCOc1cc(F)ccc1NCC(=O)N1CC(C)CC(C)C1 +CCCC(NC(N)=O)C(=O)N(C)Cc1sccc1Br +Cn1cc(C(=O)Nc2nc3c4c(ccc3s2)CCCC4)ccc1=O +Cc1cc(C)n(-c2ccc(NC(=O)c3nccnc3N)cn2)n1 +O=C(c1ccccc1)N1CCN(Cc2cccc3cccnc23)CC1 +O=C(c1cccnc1N1CCOCC1)N1CCC2(CCCCC2)C1 +COc1ccc2oc(=O)c(-c3n[nH]c(-c4ccncc4)n3)cc2c1 +c1cc(CN2CCCC(CN3CCOCC3)C2)c2c(c1)OCO2 +Cc1ccccc1CC(C)NC(=O)CSc1nnc(N)n1C1CC1 +CCOC(=O)c1csc(NC(=O)c2cccc3ccc(C)nc23)n1 +Cc1ccc(C(=O)N2CCCN(C(=O)c3ccc(F)cc3)CC2)cn1 +COc1cccc(NC(=O)COC(=O)c2ccc(NC(N)=O)cc2)c1 +Cc1cc(C)n2nc(SC(C)c3nc(C(C)C)no3)nc2n1 +O=c1n(Cc2ccccc2)c2ccncc2n1Cc1ccccn1 +CCN(CCOc1ccc(C#N)cc1)CC(F)(F)F +COc1ccc(-c2noc(C(=O)NC(C)C)n2)cc1OC +CCOC(=O)c1cccc2nc(N)n(-c3ccncc3)c12 +CN(Cc1cc(Br)cn1C)C(=O)c1ccc2[nH]cnc2c1 +O=C(c1ccncc1)N1CC(n2cc(-c3ccccc3)nn2)C1 +COc1ccccc1N(C)c1ncc(C(C)=O)s1 +O=C(NC1CCCC1)c1noc2c1COc1ccccc1-2 +CCC(=O)N1CCC2C(=O)N(Cc3ccc(OC)cc3)CCOC2C1 +O=C1COc2cc(C(=O)N3CCC(O)(C(F)(F)F)CC3)ccc2N1 +CNC(=O)NCC(=O)N(Cc1ccc(C(C)C)cc1)C1CC1 +COC(=O)CCC(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +CC(CNC(=O)Nc1cnn(-c2ccccc2)c1)Cn1cccn1 +Cc1cc(CNC(=O)CCc2nc(=O)c3c(C)c(C)sc3[nH]2)on1 +CC(C(=O)OC(c1ccccc1)c1ccccn1)c1ccsc1 +Cc1cc(C)cc(C(=O)NCc2ccc(NC(=O)c3ccco3)cc2)c1 +CC(C)CCN1CC(C(=O)NCc2ccc(F)cc2)CC1=O +O=C(CCC(=O)NC1CCCC1)NCC1CCCCC1O +CC(C)Cc1cc(C(=O)Nc2cc(-c3cccnc3)n[nH]2)[nH]n1 +O=C(NC1CC1)c1nc(-c2ccc(F)cc2)cs1 +Cc1ccc(C(=O)NCC2(CC(C)C)CCCC2)c(=O)[nH]1 +Cn1nccc1CNC(=O)Cn1nc(C(F)F)cc1C(F)F +CCn1nc(C)cc1C(=O)NCc1ccc(OC)cc1 +Cc1noc2ncnc(NCc3nc(Cc4cccs4)no3)c12 +CC(C)CN(CC(N)=O)S(=O)(=O)c1ccc(C#N)cc1 +CC(C)Oc1ccc(N2CC(C(N)=O)CC2=O)cc1 +COc1cccnc1NC(=O)C1Cc2ccccc2C(=O)O1 +Cc1n[nH]c(C(=O)NCCC(=O)OC(C)C)c1Br +COc1nn(C)cc1C(=O)Nc1ccc(S(C)(=O)=O)cc1 +CCc1cnccc1C(=O)Nc1nn(C)cc1C(N)=O +CC(CNC(=O)CCC(=O)c1ccc(F)c(F)c1)c1cccs1 +O=C(NCC1CCCO1)c1csc(COc2ccccc2)n1 +CCN(C)c1ccc(C(=O)NC(C)c2ccco2)cc1 +CCN(Cc1ccncc1)c1nc(C)c(C(C)O)s1 +Cc1ccccc1OCCN(C)C(=O)c1ccc2ncsc2c1 +CC(=O)c1ccccc1NCC(=O)Nc1cccc(C#N)c1 +COCCNC(=O)NCC#Cc1ccc(N(C)C)cc1 +COC(=O)C(CC(=O)c1ccc(C)cc1)n1nc(C)cc1C +CCOCCSc1nnc2n(C)c(=O)c3ccccc3n12 +COCCNC(=O)CCC(=O)c1c(C)c(C)cc(C)c1C +COc1ccccc1OCCN(C)Cc1cnc2ccc(C#N)cn12 +Cn1ncc2c(=O)n(CC(=O)NC(c3ccccc3)C3CC3)cnc21 +Cc1ccc(-n2nnnc2SCC(=O)N2CCCCC2)cc1 +Cn1cc(C2CCCN2C(=O)CCc2nc3ccccc3o2)cn1 +O=C(Nc1ccc2c(c1)COC2)c1cc(F)ccc1O +CCOC(=O)C1=C(CNc2cccc(Cl)c2F)NC(=O)NC1C +O=C(c1cccc(S(=O)(=O)NC2CC2)c1)N1CCCC(O)C1 +COc1ccccc1CN(Cc1cccs1)C(=O)C1CCCO1 +Cc1c(C(=O)NCC(C)(C)c2cccs2)cnn1C +COC(=O)Cc1ccc(NC(=O)Cc2ccccc2C)cc1 +COc1ccc(C(O)CN2CCOCC2)c(OC)c1 +COc1ccc(NC(=O)c2cc(C3CC3)[nH]n2)cn1 +O=C(c1cc(F)cc(F)c1)c1ccccc1CN1CCOCC1 +CCOC(=O)C1(NC(=O)c2ccc(-n3cncn3)cc2)CCCC1 +COC(=O)C1CC(c2ccccc2)CN1C(=O)c1ccccc1 +CS(=O)c1ccc(C(=O)N2CCN(Cc3ccncc3)CC2)cc1 +Cc1ccc(NC(=O)CCSc2nnc3ccccn23)cc1 +Cc1ccc(CN(C)C(=O)c2nc(N3CCCCC3)ncc2Cl)o1 +C#CCOc1cccc(NC(=O)Cc2ccc(F)cc2F)c1 +CC(C)c1ccccc1NC(=O)NCc1ccc(-n2cncn2)cc1 +CCOC(=O)c1ccc(Nc2ccc(N)c(C)n2)cc1 +CC(C)CC(=O)Nc1ccc(C(=O)Nc2ccc(O)cc2)cc1 +COCCNC(=O)c1ccc(-c2cnn(C(C)(C)C)c2)nc1 +Cc1c(C(=O)Oc2ccc3ccc(=O)oc3c2)cnn1-c1ccncc1 +COC(=O)CSc1nnc(CSc2ccccc2)n1C +CC(C)(C)c1nnc(SCC(=O)Nc2ccc(CC#N)cc2)n1N +Oc1cccc2c1CCNC2COc1ccccc1 +N#Cc1ccccc1OCc1ccc(C(=O)NCc2cscn2)o1 +COCc1cccc(-c2nc(C)nn2CC(F)(F)F)c1 +C=CCn1c(C)nnc1SCC(=O)Nc1cccc(NC(C)=O)c1 +Cc1cc(C)cc(-c2cc(NC(=O)CCc3cnn(C)c3C)[nH]n2)c1 +CC(CO)NC(=O)CNC(=O)c1cccc(F)c1 +Cc1cc(CS(=O)(=O)N(CCC#N)C2CC2)no1 +Cc1cc(NC(=O)N(C)C(C)c2cccnc2)ccc1-n1cnnn1 +Cn1nnn(-c2ccc(NC(=O)c3ccc4c(c3)OCO4)cc2)c1=O +Cc1ccc(F)cc1CC(=O)N(C)Cc1ccncc1C +O=C(NCc1cn2ccccc2n1)c1ccc(-c2ccco2)[nH]c1=O +COc1cccc2c(=O)c(C(=O)Nc3ccccc3C)cn(C)c12 +CCn1ncc(-c2c(OC)cccc2OC)c(C#N)c1=O +N#Cc1cccc(NC(=O)c2cc(-c3ccccc3)[nH]n2)c1 +CCn1nc(C)c2c(C(=O)N3CCCC(C)C3)cc(C)nc21 +C=C(C)COc1ccc(NC(=O)N2CCN(C)C(=O)C2C)cc1 +COC(=O)c1ccoc1Cn1ccc(-c2ccc(F)cc2)n1 +Cc1ccncc1NC(=O)Nc1ccc(NC2CCOCC2)cc1 +CC1CN(C(=O)Cc2csc(-c3ccccc3)n2)CC(C)O1 +CC(=O)NC(Cc1cc(N(C)C)nc(C2CC2)n1)c1ccccc1 +CC(C)c1nnc2n1CCN(Cc1nnc(C(C)(C)C)o1)C2 +CN1CCN(S(=O)(=O)c2ccc(N)c(C(N)=O)c2)CC1 +Cc1ccsc1CN(CC(=O)N(C)C)CC(F)(F)F +O=C1C(NS(=O)(=O)Cc2ccccc2F)CCN1c1ccccc1 +Cc1ccc(C)c(NC(=O)N2CCN(C(=O)c3nonc3N)CC2)c1 +COc1ccc(SCC(=O)Nc2c(C)cccc2C)cc1 +CCN(C(=O)c1cc(C)ccc1O)C(C)COC +Cc1nn2c(-c3ccco3)nnc2c2ccccc12 +O=C(Cc1cccc(F)c1)N1CCN(C(=O)Cn2cnnn2)CC1 +CCC(=O)NC1CCCN(C(=O)C2Cc3ccccc3N2C(C)=O)C1 +O=C(Nc1ccc2c(c1)CCC2)c1ncccc1O +COC(=O)CCCNC(=O)c1cc(=O)[nH]c2ccccc12 +COc1ccc(F)cc1CN1CCNc2ccccc21 +CC(C)Cc1ncc(CN2CCCN(C(N)=O)CC2)s1 +Cc1nc2ccccc2n1CC1CCN(C(=O)NC(C)C)CC1 +CC(C)(C)NC(=O)c1cccc(NC(=O)c2ccncc2)c1 +CCCOc1cccc(NC(=O)c2ccc(S(C)=O)cc2)c1 +COc1ccc(OCCN(C)C(=O)c2ccccc2N)cc1 +Cn1cnnc1-c1cccc(NC(=O)c2ccc(C#N)cc2)c1 +CC1CN(C(=O)c2nn(C)c3c2CCCC3)CC1(C)O +COC(=O)CC1CN(Cc2c[nH]nc2-c2ccccc2F)CCO1 +Cc1cc(C)n(-c2ccc(NC(=O)c3sc(C)nc3C)cn2)n1 +O=C(COc1ccccc1)N(Cc1ccco1)c1ccccn1 +NC(=O)Nc1ccc(C(=O)OCc2ccccn2)cc1 +Cc1ccc(NC(=O)c2nnn(-c3ccccc3)n2)cc1 +CCCn1nccc1NC(=O)N1CCCN(CC(=O)OC)CC1 +CC(=O)N1CCN(C(=O)CCn2nc(C)cc2C)CC1 +CCC(NC(=O)CNC(=O)c1ccc(Cl)cc1)c1ccc(C)cc1 +COc1ccc(OC(=O)c2cnn(-c3ccccc3)c2C)cc1 +CC(=O)Nc1ccc2ccccc2c1Br +C=CCN(CC=C)C(=O)c1cc(Br)c[nH]1 +COCc1nn(-c2ccc(C(=O)OC)cc2)c(N)c1-c1ccccc1 +Cc1cccc(N(C)C(=O)c2cnc3c(cnn3C(C)C3CC3)c2)n1 +O=C(COc1cccc2ccc(=O)[nH]c12)Nc1cccc2ccccc12 +Fc1ccc(C2NCCc3ccc4c(c32)CCO4)cc1 +CC(=O)c1c(C)[nH]c(C(=O)NC2CCCC(C)C2)c1C +O=C(OCc1ccccc1)n1nnc2ccccc21 +CC(=O)NCC1CN(Cc2sc3ccccc3c2Cl)CCO1 +Cc1ccc(CN2C(=O)C(=O)c3cc(C)ccc32)cc1 +CCc1cccc(CC)c1NC(=O)CNc1cccc(C#N)c1 +CC1CN(CC(=O)NCc2cnn(-c3ccccc3)c2)CC(C)O1 +CC(c1nnnn1-c1ccccc1)N1CCN(c2ncccn2)CC1 +OCCNc1nc(N2CCOCC2)c2ccccc2n1 +CCN(C)C(=O)C1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 +COc1cc(C=C2CCn3c2nc2ccccc2c3=O)ccc1O +C#CCN1CCN(C(=O)NC2CC(C)(C)c3ccccc32)CC1 +COc1ccc(NC(=O)c2cc(-c3cccc(Cl)c3)nn2C)cn1 +Cc1cc(C)n2c(CCCNC(=O)c3ccco3)nnc2n1 +CCOc1ccc(C(=O)CCc2nc(-c3ccc(C#N)cn3)no2)cc1 +COc1ccc(C(=O)Nc2cc3c4c(c2)CCN4C(=O)CC3)cc1 +Cc1cc(N)n(-c2ncnc3c2cnn3-c2ccccc2)n1 +COc1ccnc(NCc2cccnc2Oc2ccccc2C)n1 +N#CCC1NCCc2cc(C(F)(F)F)c(F)cc21 +CC(C)(C)c1nnc(NCc2cnn(-c3ccccc3)n2)o1 +CCn1ncc(Cl)c1C(=O)NCc1ccccc1F +CC12COC3(C(=O)N4CCCCC4)CC1CCC32C +O=C(Cc1ccc2c(c1)CCC(=O)N2)NCCCO +O=C(Nc1cc(Cl)ccc1F)C1CC1c1ccco1 +CCOc1cccc(N2CCn3c2nc2c3c(=O)n(C)c(=O)n2C)c1 +Cc1cc(C)nc(NC(=O)Cn2nc(C)c(Br)c2C)n1 +COc1ccc(NC(=O)c2c(C)oc3c2CCCC3)cc1 +CCc1cnc(NC2COC3(CCCCC3)C2)nc1 +CN(C(=O)OC(C)(C)C)C1CCCN(c2ncccn2)C1 +COC(=O)c1nn(-c2ccc(F)c(Cl)c2)cc1O +CCOc1ccc2c(c1)C(c1ccc(=O)[nH]n1)NCC2 +O=C(Nc1cnn(CCc2ccccc2)c1)c1ccccc1 +CC(C)C(=O)N1CCN(Cc2nc3cc(Cl)ccc3n2C)CC1 +O=C(NCc1cc2ccccc2o1)Nc1ccc(Cn2cccn2)cc1 +CC1CCc2onc(C(=O)Nc3nc4ccccc4n3C)c2C1 +Cc1cccc(C)c1NC(=O)COC(=O)Cc1c[nH]c2ccccc12 +COC(C)(C)c1noc(Cc2c[nH]c3cccc(C)c23)n1 +Cc1ccc(NC(=O)n2cncn2)cc1NC(=O)n1cncn1 +CCCc1[nH]c(=O)c(C(=O)Nc2cccc(C)c2)cc1C(=O)OCC +COc1cccc2cc(-c3cn4ccc(C)cc4n3)c(=O)oc12 +CC(C)CC(C(=O)NC1CCC(C)CC1)N1CCCCC1=O +CN(C)C(=O)N1CCC(C(=O)Nc2ccccn2)CC1 +CCCNC(=O)Nc1ccc(N(C)C(=O)OC)cc1 +CC(C)(C)n1cc(C(=O)N(Cc2ccc(Cl)cc2)C2CC2)cn1 +OCCc1ccccc1NCc1ccc(F)cc1F +CC(=O)c1cccc(NCCC(O)c2cccc(N)c2)c1 +CCC(C)NC(=O)NCc1ccc(-n2cccn2)nc1 +CCN(CCn1cccn1)C(=O)Nc1ccc(C(=O)OC)cc1C +CCc1nc(CNc2ccccc2C(N)=O)cs1 +O=C(CNc1c(F)cccc1F)NCc1ccc(F)cc1 +COc1ccccc1C(=O)Nc1ccc(CN2CCCC2=O)cc1 +O=C(Nc1cccc(OCc2cccnc2)c1)N1CCCC(CO)C1 +N#CCCN(CCC#N)CC(O)c1ccc(Cl)cc1Cl +O=C(CC1C=CCC1)NCCc1nc2ccccc2[nH]1 +Cc1ccc(F)c(NC(=O)c2cc(C)nc3c2c(=O)[nH]n3C)c1 +CNC(=O)Cn1ccnc1-c1ccc(C(F)(F)F)cc1 +Cc1ccc(NC(C)C)c(C(=O)NCCCn2nc(C)cc2C)c1 +Cc1cc(C)c2sc(NC(=O)COc3ccccc3)nc2n1 +Cc1ccc(C)c(NC(=O)CSc2nnc(Cn3cncn3)o2)c1 +Cc1cc(C(C)NC(=O)CCc2ccccc2O)c(C)o1 +CCOC(C)C(=O)Nc1ccnn1Cc1ccc(C(F)(F)F)cc1 +CSc1ncccc1C(=O)NC1CC2CC1C1CCCC21 +O=C1CCCCC1(CCc1ccncc1)CCc1ccncc1 +COCC(O)CN(C)C(=O)Nc1ccccc1SC(F)F +COc1ccccc1S(=O)(=O)NCc1cnn(C)c1 +Cc1nc(-c2ncccn2)sc1C(=O)N1CCN(CC(C)O)CC1 +Cc1cccn2c(=O)c3cc(C(=O)NCC4CCCO4)n(C)c3nc12 +N#CCCN(CCC(F)(F)F)C(=O)c1cc2c(F)cccc2[nH]1 +Cc1cccc(C2CCCCCN2C(=O)CN(C)S(C)(=O)=O)c1 +O=S(=O)(NCc1cc2c(s1)CCCCC2)C1CCOC1 +Cc1noc(NC(=O)c2cccc(OCc3ccccc3C#N)c2)n1 +COc1ccccc1C1(CNS(=O)(=O)N2CCCC2)CC1 +Cc1ccc(NCc2nnc(-c3ccccc3)o2)c(F)c1 +O=C1CN(C(=O)COC(=O)C2CC2c2ccccc2F)CCN1 +COCCC1(O)CCN(C(=O)NCc2ccccc2)CC1C +CC(C)CC(C)CC(=O)N1CCC(C(N)=O)c2ccccc21 +CC(Nc1ncccc1Br)C1CCCO1 +Cc1ccc(-n2ccnc2SCC(=O)N2CCC(O)C2)cc1C +CC(C)C(=O)N1CCc2cc(CNS(C)(=O)=O)ccc21 +CC(C)(C)C(=O)Cc1ccc(S(N)(=O)=O)cn1 +CCC(=O)NCC(=O)NCCOc1cccc2c1OC(C)(C)C2 +Nc1ccc2[nH]c3nnc(CCc4ccc5ccccc5n4)n3c2c1 +CC(=O)Nc1ccc(SCC(=O)NCc2ccco2)cc1 +CCn1c(=O)c(C)nc2cc(C(=O)NC3CCCCCC3)ccc21 +O=C1NCCCCC1NS(=O)(=O)c1ccc2c(c1)CCC2 +Cc1cnc(C(=O)N2CCC3C2CCC(=O)N3CC2CC2)cn1 +COCCC1(CO)CCCN(C(=O)c2ccn(C)n2)C1 +O=C(NCc1cccs1)c1ccccc1C(F)(F)F +CC1(C)CN(C(=O)c2cc3c([nH]c2=O)CCCC3=O)C1(C)C +CCC(C)c1noc(C2CCCCN2C(=O)CCc2cnn(C)c2)n1 +O=C(Nc1ccccc1N1CCCC1=O)C1CC1(Cl)Cl +CC(C)(C)C(=O)NCCCC(=O)Nc1c(F)cccc1N1CCCC1 +CC(C)(C)OC(=O)N1CCCC2(C)C(O)CCCC12 +Cn1c(=O)[nH]c(=O)c2c1nc1[nH]c(-c3ccc(F)cc3)cn12 +C#CCn1cc(CN(C)C(=O)NCC2CN3CCCCC3CO2)cn1 +COc1cc(CO)ccc1OCC(=O)NC1CCCCC1 +COc1ccc(Cl)cc1CC(=O)NCC(C)O +CC(C)(C)OC(=O)Nc1ccc(CC(=O)N2CCNCC2)cc1 +CCNC(=O)C1CCCN(S(=O)(=O)c2ccc(C)s2)C1 +CCC1Oc2cc(N)ccc2N(Cc2ccccc2F)C1=O +CCCC(NC(=O)c1ccccn1)c1nnc2ccccn12 +CN(C(=O)CNC(=O)c1ccccc1)c1ccccc1 +COc1c(Cl)cccc1NC(=O)c1cc(Br)cn1C +COCC(=O)Nc1sc2c(c1C#N)CCC(C)C2 +O=c1cc(CO)n(CCc2ccccc2)cc1OCc1ccccc1 +CC(=O)N1CCN(CCOc2ccc(F)cc2)CC1 +COCc1oc(-c2ccc(OC)c(F)c2)cc1CC#N +CCNC(=O)NC1(C(=O)NCCc2cccnc2)CCCC1 +Cc1noc(C(C)OC(=O)CCC2CCCC2)n1 +COCCN(C(=O)c1ccc2[nH]cnc2c1)C1CC1 +Cc1csc(CNC(=O)NC(C)c2ccc3c(c2)OCCCO3)n1 +O=C(CCCOc1ccc(Cl)cc1)NC1CCCc2occc21 +Cc1cccc(-c2nc(C(C)C)no2)c1NC(=O)C1CC2CCC1O2 +CCOc1ccc(-n2cc(-c3ccc(OC)c(OC)c3)[nH]c2=O)cc1 +CCOCC(=O)Nc1ccc(-c2nccs2)cc1 +Cc1ccc2nc(N(C)Cc3nc(-c4ccccn4)no3)sc2c1 +O=C(COn1nnc2ccc(Cl)cc21)N1CCOCC1 +CCn1c(SCC(=O)Nc2ccccc2)nc2c(c1=O)SCC2 +C=CCCCN(C)C(=O)NCc1cc(C(C)C)no1 +CCC(C)NC(=O)CN1CCN(C(=O)c2cc(F)ccc2C)CC1 +CCC(=O)NCC(=O)Nc1cc(Cl)c(O)c(Cl)c1 +COc1ccc(S(=O)(=O)NCC(O)Cc2ccccc2)cc1F +C#CCN(Cc1ccc(F)cc1)C(=O)c1cn2cccnc2n1 +CCOCC(=O)Nc1ccc(Cl)c(OC(F)F)c1 +NC(=O)C1CCCCN1C(=O)CSc1ccc(C(F)(F)F)cn1 +Cn1cc(S(=O)(=O)NCc2ccoc2)c(=O)n(C)c1=O +CC1(C)OC(=O)c2c(cc(NCC(N)=O)oc2=O)O1 +Cn1cnnc1-c1ccccc1NCc1cc[nH]n1 +O=C(Nc1ccc(C(=O)c2ccncc2)cc1)OCc1ccccc1 +O=C(NCCS(=O)(=O)c1ccc(F)cc1)c1ccccc1Cl +CC(C)(C)C(=O)Cn1nnn(-c2cccs2)c1=O +CCOC(=O)Cc1csc(NC(=O)N2CCOCC2)n1 +CCc1ccc(CN2CCN(Cc3cc(C(N)=O)cs3)CC2)s1 +Cc1noc(C)c1C(=O)N1CCC(c2nnc3ccccn23)CC1 +CCn1cc(Cl)c(C(=O)Nc2nc3ccccc3s2)n1 +CC(=O)NCC(=O)N=c1sccn1Cc1ccccc1Cl +N#Cc1nc(-c2ccccc2Cl)oc1NCC1CCCO1 +CC1CCCC(CO)(Nc2cc(N)cc(F)c2)C1 +Cc1ccc(C(=O)N(C)CCOCC2CC2)c(=O)[nH]1 +Cc1c(C(=O)N2CCC2)nnn1-c1ccc2ncccc2c1 +CC(C)Oc1ncnc(Nc2ccc(F)cc2)c1N +CCc1nc(C)cn1S(=O)(=O)c1ccc(C(C)C)cc1 +COc1cc(C(=O)Nc2ccn(CC#N)n2)nn1C +COc1ccc(-c2n[nH]cc2CN2CCOC3(CCCC3)C2)cc1 +CC1CC(Nc2ccc(NC(=O)c3ccc(Cl)cc3)cc2)C(=O)O1 +CC(=O)N1CCCC(c2cc(Nc3ccccn3)nc(C)n2)C1 +COc1ccc(NC(C)=O)cc1NCc1nc(C)cs1 +CCCS(=O)(=O)Nc1cc(S(=O)(=O)CC)ccc1O +c1cnc2ncc(CN3CCOC4(CCC4)C3)n2c1 +CN(CC(O)C1CC1)C(=O)c1ccc(OCC2CCCCC2)cc1 +Cc1noc(C)c1-n1c(Cc2ccccc2)n[nH]c1=O +O=C(c1nccn2ccnc12)N1CCC(c2ccccc2F)C1 +CCC(C)NC(=O)C(C)NC(=O)NC(C)c1ccc(F)cc1Cl +CC1(NC(=O)c2ccc(CNC(N)=O)cc2)CCCC1 +CC(C#N)NC(=O)c1ccccc1Br +COc1ccc(-c2nnc3c(N)cccn23)cc1OC +COc1ncccc1C(=O)N1CCC2OC(C)CC2C1 +Cc1ccc(C(=O)Nc2ccc(-n3cnnn3)cc2)o1 +NC(=O)c1ccc(CNC(=O)c2cccs2)cc1 +COc1ccc(C)cc1CN1C(=O)CNc2ccccc21 +O=C(NCCCn1ccc2ccccc21)C1CCOCC1 +COc1ccc(S(=O)(=O)NCc2ncoc2C)c2ccccc12 +Cc1cc(C(=O)NC2CCN(C(=O)NC3CCCCC3)CC2)n(C)n1 +O=C(NC12CC1CN(C(=O)c1ccco1)C2)c1ccoc1 +Cc1c(COc2nnc(-c3ccccc3)o2)cnn1C +CC(C)(C)OC(=O)NC(CO)C(=O)Nc1ccccc1 +COc1ccnc(NCc2ccc(Cn3cnc4ccccc43)cc2)n1 +COCc1nc2cc(Cl)cnc2n1CCCC#N +Cc1noc(-c2ccc(=O)n(Cc3ccccc3C)n2)n1 +CCc1oncc1C(=O)NCC1CCN(c2cnn(C)c(=O)c2)C1 +CS(=O)(=O)c1ccccc1C(=O)NCC1(c2ccccc2)CCC1 +O=C(CC1CCCC1)NCC(=O)Nc1ccc2c(c1)CC(=O)N2 +COc1c(C)cnc(CNC(=O)NCCOc2ccccc2)c1C +NS(=O)(=O)c1ccc(CNC(=O)c2n[nH]c3c2CCCCC3)cc1 +O=C(CCC(=O)N1CCOCC1)NC1C2CC3CC(C2)CC1C3 +CC(NC(=O)Cc1c[nH]c(=O)[nH]c1=O)c1cc2cc(Cl)ccc2o1 +O=C(NCc1ccncc1)C1CCCN(C(=O)Nc2cccs2)C1 +O=C(Nc1ccccc1)C1CCN(c2ccc3nncn3n2)CC1 +O=C(Nc1ccc2c(c1)COC2)C1Cc2cccc(F)c2O1 +CCOC(=O)c1nnn(Cc2cccc(F)c2)c1N +CC(O)CN1CCN(C(=O)c2ccc(Cn3cccn3)cc2)CC1 +Cc1cc(Oc2ccccc2F)nc(C2CCCN2CC(N)=O)n1 +COc1ccc(C)cc1S(=O)(=O)NCc1cc(C)oc1C +COc1cccc(OCC(=O)Nc2ccnn2C(C)C)c1 +CCCC1CC1NC(=O)C(CC(C)C)N1CCCCC1=O +CC(=O)c1nnn(CC(=O)Nc2cc(C)ccc2C)c1C +Cc1nc(NCCCC(=O)OC2CCCC2)c2cnn(C)c2n1 +Cc1ccc(NC(=O)c2c(N)oc3ccccc3c2=O)cc1 +OC(COc1ccc(F)cc1)CN1CCOC(Cn2cncn2)C1 +CN(C(=O)CCC1CCCO1)c1ccc(F)c(F)c1 +CN1CCOC(CNc2ccc3nnc(-c4ccccc4)n3n2)C1 +CC(C)c1nnc(NC(=O)c2csc3c2CCCC3)s1 +Cc1n[nH]c(C)c1NC(=O)N(C)CCOCC1CC1 +CCCN(CC(=O)NC)C(=O)c1c(C)noc1C(C)C +COC(=O)c1ccc(CSc2cc(C)ncn2)o1 +COC(=O)C(NCC(F)(F)F)c1ccc(OC)c(O)c1 +CC(C)CC(=O)N1CCN(C(=O)c2cnn3ncccc23)CC1 +CCCCNC(=O)C1CCN(S(=O)(=O)N(C)C)CC1 +CSc1nc(C)cc(C(=O)NCCCN2CCOCC2)n1 +COc1ccnc(NC(=O)Cc2ccc(Cl)cc2)c1 +Cc1[nH]c(-c2cccc(Cl)c2)nc1C(=O)Nc1ncnn1C +CCC(C)c1ccccc1OCC(=O)Nc1cccc(N)c1 +O=C(CCN1CCN(c2ncccn2)CC1)N1CCc2ccccc21 +O=C(Oc1ccc(-n2cnnn2)cc1)c1cccc(OCC(F)F)n1 +COc1ccc(S(=O)(=O)Nc2ncccc2C)cc1C +O=C(c1cccnc1)N1CCN(c2nnc3ccccn23)CC1 +CCC1(CC)C(NC(=O)Nc2c(C)n[nH]c2C)C(C)C1OC +CC(C)(C)n1ccnc1C(=O)Nc1cccc(F)c1 +CNS(=O)(=O)c1cccc(C(=O)N(C)Cc2ccc(C)o2)c1 +O=C(Cn1ncccc1=O)Nc1ccc(C(F)(F)F)cc1 +CNS(=O)(=O)c1ccc(C(=O)NC(C)C(C)C)o1 +CC(Oc1cccc(C(C)(C)C)c1)C(=O)NCCCO +O=C(NC1CC1)c1cccc(OC(=O)c2coc(-c3ccccc3)n2)c1 +Cc1cc(C)c(CNC(=O)c2cncc(Br)c2)c(=O)[nH]1 +Cc1ccccc1NC(=O)C1(C)Sc2ccccc2N(C)C1=O +CN(C)c1ccc(C2CN(C(=O)c3cncs3)CCO2)nc1 +Cc1cccc(NC(=O)c2ccc3nccnc3c2)n1 +CCC(=O)NCCn1nc(C2CC2)n(-c2ccccc2)c1=O +O=C(Cn1c(=O)[nH]c2ccccc21)NCCc1cccc(Cl)c1 +COc1ccccc1CC(=O)N1CCCCC1CNS(C)(=O)=O +Cc1noc(C)c1S(=O)(=O)Nc1cc(Cl)ccc1Cl +Cc1csc(=O)n1CC(=O)N(C)Cc1ccccn1 +CC(=O)N(C)CC(=O)NCCCNc1ncccn1 +CN(Cc1ccccc1)C(=O)c1cc(C2CC2)nn1-c1ccccc1 +CCc1nc(C)c(C(C)OC(=O)CN(C)C(=O)c2ccccc2)s1 +Cc1c(C(=O)Nc2cccc(-c3cn[nH]c3)c2)cnn1C +O=C(c1ccc2c(c1)COC2)N1CCCC(c2ccn[nH]2)C1 +Cc1ccc(S(=O)(=O)N(C)C)cc1C(=O)Nc1ccccc1 +CCOCCOc1c(C(C)=O)ccc2ccccc12 +CC1c2ccccc2CCN1C(=O)CCN1CCOCC1 +COc1ccc(C(C)=O)c(OC(C)C(=O)Nc2cccc(C#N)c2)c1 +CCCC(C)(CO)NC(=O)NCc1ccc(C(=O)NC)cc1 +COC(=O)c1cnn(-c2nc3ccc(OC)cc3s2)c1N +O=C(N1CCN(c2cccc(Cl)c2)CC1)C1(O)CCCC1 +NC(=O)NCCC(=O)N1CCN(S(=O)(=O)c2cccs2)CC1 +CCc1cnc(N)nc1N1CCCC(O)(CC)C1 +Cc1cccc2c(=O)n(CC(=O)NCCc3cccnc3)cnc12 +O=C(C1CC1)N1CCCN(S(=O)(=O)c2ccccc2)CC1 +NS(=O)(=O)c1cc(C(=O)N2CCCC2)cs1 +O=C(Cn1cccn1)N1CC(n2cc(-c3ccccc3)nn2)C1 +COc1ccc(S(=O)(=O)NCCc2csc(C)n2)c(C)c1 +COc1ccc(N(C)C(=O)c2cccc(-c3ccoc3)c2)cn1 +CN(CCc1ccccc1)S(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +COc1ccc(OC)c(C2CCCN2C(=O)NCc2cscn2)c1 +CN(Cc1ccccc1Br)C(=O)c1ccncc1F +O=C(Nc1ccc(-n2cccn2)cc1)c1nnc2ccccc2n1 +CCOC1CCN(Cc2ccc3c(c2)OCO3)C1Cc1cnn(C)c1 +CCc1ccc(C2Nc3ccccc3C(=O)N2CCOC)cc1 +COC(=O)CSc1nc(-c2ccco2)cc(-c2ccco2)c1C#N +O=C(Nc1nncs1)c1ccc(Cn2ccnc2)cc1 +CCCC1CCC(NC(=O)CSc2nncs2)CC1 +CC(C)c1noc(-c2ccn3c(CC(=O)NC4CC4)nnc3c2)n1 +O=C1CCc2cc(OCC(=O)N(CC(F)(F)F)C3CC3)ccc2N1 +COCc1ccccc1CNC(=O)Nc1cc(OC)ccc1Cl +COC(=O)c1ccc(CN(C)Cc2nnc(C3CC3)n2C)cc1F +O=C(Nc1cc2c(cc1C(O)C1CC1)OCCO2)C1CC1 +CNC(=O)c1ccc(Cl)c(NC(=O)Cc2cccc(OC)c2)c1 +C=CCOC(=O)C1=C(C)Nc2ncnn2C1c1cccc(OC)c1 +O=C(NCCC1=CCCCC1)c1nnc(Cc2ccc(Cl)cc2)o1 +CC(C)CCn1cc(C(=O)N(C)C)c(=O)c2c(N)cccc21 +COc1ccc(OC)c(NCCCc2ccc(C)o2)c1 +CCOc1ccc(-n2ccnc2S(C)(=O)=O)cc1 +CCOCCCNC(=O)c1cc2ccc3cccnc3c2[nH]1 +COc1ccc(-c2nnc(SCC(=O)Nc3ncccn3)o2)cc1 +O=C(Nc1cnn(Cc2ccncc2)c1)Nc1ccc(F)cc1F +COCc1ccc(C(=O)N2CCN(Cc3ccccc3C)CC2)s1 +NC(=O)c1ccc(NC(=O)CC2=CCCCC2)c(F)c1 +COC(=O)N1CCCC(C(=O)Nc2ccccc2C(=O)C(C)C)C1 +O=C(NCc1nccs1)c1cc2c(s1)CCCCC2 +COC1CCN(C(=O)c2cc(-c3ccccc3F)on2)CC1 +CCNC(=O)c1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)c(C)c1 +C=CCN1CCC2(CCN(C(=O)C3CCOCC3)CC2)C1=O +CCOc1ccc(NC(=O)Cc2cccc(F)c2F)c(C(N)=O)c1 +Cc1cc(=O)c(N)nn1-c1ccc(Cl)cc1Cl +CN(Cc1ccc(F)cc1)S(=O)(=O)c1cccc(N)c1 +COCCN(C)C(=O)Nc1cc(C)c(Cl)cc1OC +Cc1n[nH]cc1NC(=O)Nc1ccnn1CC(C)C +Cc1noc(COC(=O)CN(C)C(=O)c2ccccc2)n1 +CC(C)Sc1ccc(CC(=O)NCC(C)(O)C2CC2)cc1 +O=C(CC1C(=O)Nc2ccccc21)NC1CCCCCC1 +CCCc1n[nH]c(C(C)Oc2cccc(Cl)c2)n1 +CNc1ccc(Cl)c(C(=O)NCC2COCCO2)n1 +CC(=O)Nc1cc(F)c(F)cc1NCC(=O)NC1CCC(C)CC1 +CN1CC(C(=O)NCc2cccc(COC3CCOCC3)c2)CC1=O +COCCCC1CCCCN1C(=O)c1cc(=O)[nH]c2ccc(F)cc12 +Cc1cc2ncn(CC3CCN(C(=O)C4CCC4)CC3)c2cc1C +NC(=O)c1ccc(OCC(=O)Nc2ccccc2Br)cc1 +Clc1ccccc1CSc1cn2c(n1)CCC2 +O=C1CN(C(=O)c2cc3ccccc3oc2=O)c2ccccc2N1 +Cc1ccc(Cl)c(OCCc2cc(N)n(C)n2)c1 +O=C(NCc1ccc(CN2CCCC2=O)cc1)NCC(F)(F)F +Cc1[nH]ncc1S(=O)(=O)NCCCn1ccnc1 +O=C(Cc1ccc2c(c1)OCO2)N1CCCC1c1ccccn1 +CC(C)C(NC(=O)c1ccccc1)C(=O)Nc1nccn(C)c1=O +Cc1csc(SCC(=O)Nc2nnc(-c3ccccc3)o2)n1 +O=C(Nc1cnc(Oc2ccccc2)nc1)C1CC1 +COc1ccccc1-c1cnn2c(=O)c(C(C)C)c(C)[nH]c12 +Cc1cc(CNS(=O)(=O)C2CCCCC2)c(C)o1 +COC(=O)CN(CCN1CCOCC1)C(=O)c1ccc(Cl)cc1 +O=C1NC2=C(C(=O)OC2)C(c2ccc(Cl)cc2)N1 +CCn1c(CCNC(=O)C2CC(=O)N(C3CC3)C2)nc2ccccc21 +O=C(NCCn1cccc1)c1c[nH]nc1-c1ccccc1Cl +CC(C(=O)NCCC(=O)N1CCCc2ccccc21)n1cncn1 +COC(=O)CC(C)NC(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +CSc1ccc(NC(CO)Cc2c[nH]c3ccccc23)nn1 +CC(C)Oc1ncccc1CNC(=O)CC1C=CCC1 +CC(c1nc2ccccc2n1CCCO)N1CCOCC1 +CC(NC(=O)c1cccnc1)c1cccc(OCc2ccccn2)c1 +COc1ccc2cc(S(=O)(=O)NCc3cccnc3)ccc2c1 +Cc1ccc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)c(F)c1 +Nc1cc(Cl)cn2c(-c3ccc(F)c(F)c3)nnc12 +COc1cc(CNC(=O)NC(C)COc2cccc(C)c2)ccn1 +O=C(Nc1cccnc1)C1CN(Cc2cccs2)CC2OCCC21 +Cc1n[nH]c(C(=O)NC(C)c2cc(F)ccc2F)c1Br +CC(C)Cc1nnc(NC(=O)N(C)C2CCCCC2)s1 +COc1ccc(-c2c(C)cn(C)c(=O)c2C#N)c(OC)c1 +O=S(=O)(NCc1cc2ccccc2[nH]1)c1cc(F)cc(F)c1 +Cc1ccc(C#N)cc1S(=O)(=O)NCc1ncn(C)n1 +O=C(CCC(=O)c1ccccc1)NCc1ccccc1F +Cc1cc(C)c2c(-n3cccc3)c(C(=O)N(C)C)sc2n1 +CCCC(=O)Nc1cc(C(=O)N2CCCCCC2)cn(C)c1=O +CCCNc1ncnc(Nc2ccc(C)cc2)c1N +O=C(NCc1ccco1)c1ccccc1COc1ccccc1 +CN1CC(C(=O)N2CCc3nc4sccc4c(=O)n3CC2)CC1=O +O=C(Cn1nc2c(N3CCOCC3)nccn2c1=O)NC1CCCC1 +CCn1cc(C(=O)Nc2cc(F)c(F)cc2F)cn1 +CCC1CN(Cc2ccc(OC(C)C#N)cc2)CC(C)O1 +CC(C)(C)c1nc(CN2CCOC(C(N)=O)C2)no1 +NC(=O)C(CNc1ncnc2ccccc12)Cc1ccc(F)cc1 +CC1(O)CCN(C(=O)c2cnn3cc(CCO)cnc23)CC1O +O=C(NCc1ccc(-n2cccn2)cc1)c1c[nH]c2cccc(F)c12 +C#CCN1CCC(C(=O)NC2COc3c(cccc3OC)C2)CC1 +CN(C)C(=O)C1CCCN1C(=O)c1cc(Cl)ccn1 +Cc1nnc2n1CCN(Cc1ccc(Cl)c(Cl)c1)C2 +O=C(Nc1cc(-n2cnnn2)ccc1Cl)C1CC1 +O=S(=O)(NCCc1cc(Cl)cc(Cl)c1)c1cn[nH]c1 +CC(C)CC(NCc1nncn1C)c1ccccn1 +CN(Cc1cc(Br)ccc1F)c1cn[nH]c(=O)c1Cl +COc1cc(O)cc2c1CCNC2C(CO)c1ccccc1 +Nc1cc(N)nc(SCc2nc3ccccc3n2C(F)F)n1 +COC(=O)c1nnsc1NC(=O)c1ccc(Cl)c(Cl)c1 +Cc1ccccc1CCNC(=O)COc1cccc2cccnc12 +O=C(CS(=O)(=O)c1ccccc1Cl)Nc1cccc(F)c1 +CC(C)c1cc(CNC(=O)NCC(C)(O)c2ccc(F)cc2)on1 +CCC(CO)N(Cc1cnc2ccccc2n1)Cc1cccs1 +O=C(NCC1CC1)C1CCN(c2nc3ccccc3[nH]c2=O)CC1 +N#Cc1nc2cc3c(cc2n1C1CCCC1)OCCO3 +COCCNC(=O)CN1C(=O)C(C)Nc2cc(C)c(C)cc21 +CN(C)C(=O)c1ccc(N2CCOC(C(F)(F)F)C2)nc1 +Cc1ccc(C)c(SCC(=O)NCCCC(N)=O)c1 +CCCNC(=O)c1ccc(OCC(N)=O)c(OC)c1 +CC(C1CC1)N(Cc1ccccc1)C(=O)c1ccco1 +Cc1onc(-c2ccccc2)c1C(=O)NCCN1CCOCC1 +CC#CC1NCCc2cccc(Br)c21 +O=C(NCc1cccnc1)Nc1ccc(F)cc1F +CS(=O)(=O)c1cccnc1C1CCCN(Cc2cccnc2)C1 +CC(C)CCOC(=O)Cn1c(=O)n(C)c2ccccc21 +CCCCOCCNC(=O)c1c[nH]c2ccccc12 +Cn1cc(S(=O)(=O)N2CC=C(c3c[nH]c4ccccc34)CC2)cn1 +Cc1c(C)n(CCCN2CCOCC2)c2ncn3ncnc3c12 +CNC(=O)c1ccc(NS(=O)(=O)c2ccc(C)c(C)c2)cc1 +COC(=O)c1sccc1Nc1ccc(F)cc1N +Cc1occc1C(=O)NC(c1ccc2c(c1)OCCO2)C(C)C +Cc1ccc(NC(=O)CCc2cnn(C)c2C)cc1S(C)(=O)=O +CCC(=O)N1CCC(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)C1 +CNC(=O)Cc1noc(C2(c3ccc(F)cc3F)CCCC2)n1 +O=C(Cc1cccc(O)c1)NCCc1ccsc1 +N#CCc1ccccc1C(=O)Nc1ccc2c(c1)OCO2 +COc1nc2ccccc2nc1C(=O)Nc1ccc(C)cc1 +Cn1nccc1C(=O)N1CC(Oc2nc3c(Cl)cccc3s2)C1 +CS(=O)(=O)N1CCOC(CNC(=O)c2cc3sccc3[nH]2)C1 +CC(NC(=O)C1CCCN1S(C)(=O)=O)c1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)c2cccs2)cc1S(=O)(=O)N(C)C +O=S(=O)(CCc1ccccc1)N1CCCC(CO)C1 +CCCC1CN(C(=O)c2ccc(=O)n(C)n2)CCO1 +Cc1ccc(C(=O)NCC(=O)NC(C)c2cc(C)sc2C)s1 +COc1ccccc1C(=O)N1CCNC(c2nc3ccccc3[nH]2)C1 +COc1cc(NCc2cccc(O)c2)ccc1N1CCCC1=O +COc1ccc(C(=O)C(C)Sc2nnc(C3CC3)n2C)cc1 +O=C(c1scnc1C1CC1)N1CCOCC12CCC2 +CCS(=O)(=O)N1CCc2ncnc(C)c2CC1 +CC(C(=O)NCc1ccco1)n1nc(-c2ccc(F)cc2)ccc1=O +Oc1ccc2occ(-c3ccc4c(c3)OCCCO4)c2c1 +Cc1csc(CNC(=O)c2ccc(Cl)cc2F)n1 +CCCCNC(=O)CNc1cccc(C(=O)N2CCCC2)c1 +Cc1ccc(C(=O)OCC(=O)N2CCCC2)s1 +CCOC(=O)CCOc1cccc2c1OC(C)(C)C2 +Cc1cc(S(=O)(=O)N2CCC(CO)CC2)c(C)s1 +Cc1ccccc1NC(=O)c1cc2cccnc2n(C)c1=O +CCc1noc(CNc2cc(C(=O)N(C)C)ccc2OC)n1 +N#Cc1ccc(C(O)CSc2n[nH]c(=O)n2C2CC2)cc1 +CCc1cc(=O)[nH]c(CN2CCC(Nc3ccccc3OC)CC2)n1 +CN(Cc1ccsc1)C(=O)Cn1ccccc1=O +CCOc1ccc(CN(C)C(=O)Nn2cnc3ccccc32)cc1 +COCCCNS(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +COc1ccc(C(=O)N(C)Cc2ccnc3ccccc23)o1 +CC(=O)N1CCCc2cc(S(C)(=O)=O)ccc21 +CCC(C)NS(=O)(=O)c1ccc(C)c2c1CCCN2 +CCCc1nnc(SC2CCC3(CC2)OCCO3)o1 +Cc1occc1C(=O)OC(C)c1ccc2c(c1)OCCO2 +CCc1cccc2c(C(=O)COC(=O)C3CCCO3)c[nH]c12 +Fc1ccc(CC2NCCc3c2sc2ncnn32)cc1 +COc1ccc(OC)c(S(=O)(=O)Nc2nccc(C)n2)c1 +COC(=O)CCCc1ccc2c(c1)NC(=O)C(C)O2 +Cc1ccc(NC(=O)CCNC(=O)c2ccccc2C)nc1 +Nc1cc(F)c(SCc2ccccc2)c(F)c1 +CCCC(C)C(=O)Nc1ccc(OC)cc1OC +Cc1cc(C(=O)OCC(=O)NC(C)C(C)C)c(C)o1 +Cc1ccc(-c2nc(C(=O)NCCCC(N)=O)cs2)cc1 +COc1ccc(Cl)cc1NCC(=O)NCc1ccccc1CO +Cc1cccc(NC(=O)c2ccc(N(C)C)c(F)c2)c1 +CCOc1cccc2cc(C(C)NC(=O)NCc3cnn(C)c3)oc12 +COC(C)(C)CC(C)NC(=O)Cc1c(F)cccc1F +Cc1nn(C)c(C)c1S(=O)(=O)NCCc1ccc(Cl)cc1 +COc1cccc(SCC(=O)Nc2ccc(-c3nnco3)cc2)c1 +CCn1c(=O)n(CC)c2cc(NS(=O)(=O)c3ccccc3)ccc21 +COC(=O)C(C)NC(=O)Nc1cccc(Cl)c1 +CN(C(=O)c1cc(Cl)c2c(c1)OCO2)C1(C#N)CCC1 +O=C(Nc1cccc(Cl)c1Cl)c1ccc(N2CCCC2)nn1 +Nc1ccc(-c2nc(-c3cccc(F)c3)no2)cc1 +Cn1c(=O)oc2cc(NC(=O)N3CCc4ccccc4C3)ccc21 +O=C(NCCc1nc[nH]n1)Nc1ccc(F)cc1-c1ccc(F)cc1 +CCC(=O)N1CCCC(c2nc(CCNC(C)=O)cs2)C1 +COc1ccc(CCc2nc(C3CCOC3)no2)cc1 +CCCCS(=O)(=O)c1nsc(C(=O)NCCC)c1N +C=CCN(CC=C)C(=O)c1cn(CCC)c2cccc(N)c2c1=O +Cc1ccc(CNC(=O)NCC2CCCC2O)c(OC(C)(C)C)c1 +CC(=O)NC(C(=O)NCc1cccnc1Oc1ccccc1)C(C)C +Cc1ccc(CC(=O)NC(CO)CC(C)C)cc1C +CCOc1ccc(-c2nc(C(=O)N3CCOCC3)cs2)cc1 +COc1cc(C)c(C(=O)N2CCOc3ccc(F)cc32)cc1OC +CCCOC(=O)C1C(C)=NC2(O)c3ccccc3C(=O)C12O +COC(=O)c1cccc(S(=O)(=O)NCCc2cccs2)c1 +CN(C)c1cccc(C(=O)N2CCN(S(=O)(=O)C3CC3)CC2)c1 +COC(=O)Nc1cccc(NC(=O)Nc2cc(C)nn2C)c1 +COc1cccc(OCCCNC(=O)c2c[nH]c3cccc(F)c23)c1 +O=C(NCc1nnc2n1CCCCC2)c1ccc(-n2cccn2)cc1 +COc1ccccc1C(=O)CC1(O)C(=O)Nc2ccccc21 +O=C(NC(c1ccccc1)C1CC1)c1ccccn1 +CCN(C(=O)Nc1cnn(C)c1)C(C)c1cccc(OC)c1 +CC1CCN(S(=O)(=O)c2sccc2Br)CC1 +CCn1nc(C)c(NC(=O)COc2ccccc2)c1C(N)=O +N#CC1(C(=O)Nc2cccc(C(=O)N3CCCCC3)c2)CCCC1 +COC(=O)c1cc(-c2ccc(O)cc2)nc2ccccc12 +CS(=O)(=O)N1CCN(C(=O)c2cc(C3CC3)on2)CC1 +CCC(NC(=O)NCc1cc(=O)[nH]c2ccccc12)c1noc(C)n1 +CC(C)(C)c1csc(CCNC(=O)C2CC3CCC2O3)n1 +COc1ncccc1CNC(=O)NCCCn1ccc2ccccc21 +CC(C)CCCC1CN(C(=O)CCN2CCCC2=O)CCO1 +CN(C(=O)c1cccc(S(=O)(=O)N(C)c2ccccc2)c1)C1CC1 +CCCCNC(=O)CNc1cc2c(cc1Cl)NC(=O)CO2 +CN1CCN(Cc2cnc3ccsc3c2)C(C)(C)C1=O +Cc1csc(C2CN(Cc3cccc(-n4cccn4)c3)CCO2)n1 +COc1cc(C#N)ccc1OS(=O)(=O)c1ccccc1Cl +Cc1ccc(NC(=O)N2CCn3c(nn(C)c3=O)C2)c(Cl)c1 +CCC(C)c1cccc(NC(=O)N(C)C)c1OC +O=C(COc1cccc2cccnc12)N1CCCCCC1 +Cc1cccc(C(C)C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)c1 +Cc1noc(C2CCCN(C(=O)c3cccnc3N(C)C)C2)n1 +COc1ccc(F)cc1C(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +CC(=O)C(C)n1c(CNC(=O)C2CCCCC2)nc2ccccc21 +O=C(c1ccc2[nH]ccc2c1)N1CCc2[nH]c3ccnn3c(=O)c2C1 +CC(=O)c1nnn(CC(=O)Nc2cccc(Cl)c2C)c1C +Cn1nc(CNC(=O)CC2CCCCC2)c2c1CCCC2 +COC(=O)c1cccc(CCNS(=O)(=O)c2cccc(F)c2)c1 +CCOc1ccc(C(=O)NCCCS(N)(=O)=O)cc1 +CN(CC(=O)N1CCNCC1)C(=O)c1ccc(Br)cc1 +COc1cc(CNC(=O)c2ccc3c(c2)C(=O)c2ccccc2-3)ccn1 +O=C(NCc1nc2c(s1)CCCC2)c1cnc2sccn2c1=O +COC(=O)CSc1nc2cc3c(cc2cc1C)OCO3 +CC(=O)NCCCNS(=O)(=O)N(C)C(C)C +N#Cc1ccc(N2CC3OCCN(CC4CCCO4)C3C2)cc1 +Cc1ccc2c(NCC(C)O)ncc(Br)c2c1N +CCC(NS(=O)(=O)c1cc(C)cc(N)c1)C(C)C +Nc1cnn(CCOc2cccc(C(F)(F)F)c2)c1 +COCCn1cc(NS(=O)(=O)Cc2cccc(F)c2)cn1 +CC(C)(C)c1cc(NC(=O)NCC(=O)N2CCCC2)n(C(C)(C)C)n1 +Cc1ccc(CNC(=O)c2nc3c(s2)CCCN3C(=O)C2CC2)o1 +Cc1nc(CN(C)CCc2ccc(F)cc2)oc1C +COc1ccccc1OCC(=O)Nc1cnc2c(cnn2C(C)C)c1 +COc1ccc(CNC(=O)N2CCCC2c2ccsc2)cc1OC +Cc1cc(NC(=O)C2Cc3ccccc3C(=O)O2)c2ncccc2c1 +O=C(NCc1ccc(F)cc1)c1cc(F)cc(F)c1 +CCN(Cc1nc(N)c2c(C)c(C)sc2n1)CC(C)C#N +CC(C)OC(=O)C1CCCN1Cc1cncs1 +Cc1cc(C(F)(F)F)nn1CC(C)C(=O)Nc1nccs1 +O=C(NCC1Cc2ccccc2O1)c1cc(Br)c[nH]1 +N#Cc1ccccc1S(=O)(=O)NCC1CN2CCCCC2CO1 +Cc1csc(-c2cc(S(=O)(=O)N=c3cccc[nH]3)c(C)n2C)n1 +COc1cc(OC)cc(C(=O)NCC2(O)CCc3ccccc3C2)c1 +CC1CN(C(=O)OC(C)(C)C)CCN1c1ncc(Cl)cn1 +CS(=O)(=O)c1ccccc1NC(=O)c1cc(F)ccc1F +CCc1c(C)sc(NC(=O)c2cc(OC)cc(OC)c2)c1C(N)=O +Cc1nn(C)c(NS(=O)(=O)c2cccc(-n3cnnn3)c2)c1C +Cc1cc(C(=O)N(C)CCC(F)(F)F)sc1C +COC(C(=O)Nc1ccn(CCc2ccccn2)n1)c1ccccc1 +COc1ccc(NC(=O)NCc2ccncc2)cc1-n1nnnc1C +CCN(CC)S(=O)(=O)c1ccc2c3c(cccc13)C(=O)N2 +COc1cc(CNC(=O)COc2ccc(C#N)cc2)ccn1 +CN(C)c1ccc(C(=O)NC2(C#N)CCCC2)cc1F +Cc1cccc(CCNc2ccc(C#N)cc2N)c1 +Cc1cc(NC(=O)CCO)ccc1Br +O=C1CN(c2ccc3nnc(C(F)(F)F)n3n2)CCN1 +COc1cc(NC(=O)CCn2ccc3ccccc32)cc(OC)c1 +COCCN1C(=O)CCC2C1CCN2C(=O)NCc1cccc(F)c1 +CC(C)C(=O)Nc1ccccc1N1CCNC(=O)C1 +COC(=O)c1ccc2c(c1)CCN2C(=O)c1ccoc1 +CNC(=O)C1CCC(NC(=O)NC(C)c2cc(C)cc(C)c2)CC1 +CC(=O)c1cccc(S(=O)(=O)Nc2ccc3c(c2)CC(=O)N3C)c1 +CC(C)CNC(=O)C(C)Oc1cccc(Cl)c1 +Nc1ccccc1OCC(=O)NCCc1c[nH]c2ccccc12 +Cc1ccc(S(=O)(=O)N(CCC#N)CCC(F)(F)F)c(F)c1 +Cc1n[nH]c(C(=O)NCCCn2cccn2)c1Br +COc1cccc(CN2CCN3C(=O)NCC3C2)n1 +Cc1cccc(C(=O)N2CCC(c3nnc(C4CC4)o3)CC2)c1 +O=C(Nc1nc2ccccc2[nH]1)c1ccc(NC(=O)c2ccco2)cc1 +Cc1c(C(N)=O)sc2ncn(Cc3ccccc3C#N)c(=O)c12 +Cn1c(CCNC(=O)c2cc3ccccn3c2)nc2ccccc21 +CCc1ccc(CC)c(NC(=O)c2c(C)nn(C)c2OC)c1 +Cc1ccccc1NC(=O)Nc1cc(N2CCCC2)ncn1 +Cc1csc(N(CCc2ccccc2)C(=O)C2CCC(=O)N2)n1 +O=C(CCc1ccc(S(=O)(=O)NC2CC2)cc1)Nc1cn[nH]c1 +COC(=O)CCC(=O)N(Cc1ccccn1)c1ccc(Cl)cc1 +Cc1ccc(CS(=O)c2ccncc2N)cc1C +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2cc(OC)ccn2)c1C +Cc1cc(NC(=O)Cn2ccnc2)n(C2CCCCC2)n1 +Cc1cccc(Nc2nnc(SCC(N)=O)s2)c1C +CCCCc1cc(NC(=O)Cn2c(=O)[nH]c3ccccc3c2=O)[nH]n1 +O=S(=O)(NCc1cn[nH]c1)c1ccc(O)cc1 +N#Cc1ccc(F)c(CNCCc2ccccn2)c1 +CC(C)Cn1c(SCCCO)nc2ccc(Cl)cc2c1=O +Cc1sc2ncnc(SCC(=O)N(C)CCC#N)c2c1C +N#CC1CCCC1NC(=O)c1ccc(Br)cc1F +CC(Cn1cccn1)NC(=O)N1CCN(S(C)(=O)=O)CC1 +CNC(=O)c1ccc(C)c(NC(=O)c2ccc(=O)n(C)n2)c1 +Nc1ccccc1OCc1n[nH]c(-c2ccc(Cl)cc2)n1 +CCN(CC)C(=O)c1c(-c2ccccc2Cl)noc1C +CCOC(=O)CCNc1cc(Cl)ccc1OC +O=C(Nc1cnn(C2CCOCC2)c1)c1ccccc1C(F)(F)F +O=C(c1ccc(-n2cncn2)cc1)N1CCCc2ccccc21 +Cc1ccc(C)c(OCCCN2CCCS2(=O)=O)c1C +CCNc1ccc(S(=O)(=O)NC(CC)C(C)C)cc1 +Cn1ccnc1COc1ccc(CSc2n[nH]c(N)n2)cc1 +Cc1cccc(CS(=O)(=O)Nc2ccc3c(c2)C(=O)NCCO3)c1 +CC1CCCC(CNC(=O)C2CC(=O)N(C)C2)C1 +CC(Sc1ccccn1)C(=O)N1CCC(Oc2ccccc2)CC1 +N#Cc1nccnc1-c1ccc2c(c1)OCCCO2 +COc1nn(C)cc1C(=O)Oc1ccc2c(c1)ncn2C +Cc1nc(-c2cccs2)sc1C(=O)NCC(=O)NC(C)C +CC(C)Oc1ccc(-c2cnoc2N)cc1Cl +COC(=O)c1cc(C(=O)OC)cc(C(=O)OC)c1 +O=C(Nc1ccc(S(=O)(=O)C2CCCC2)cc1)Nc1cn[nH]c1 +CC(C)c1nn2c(=O)cc(CSc3n[nH]c(N)n3)nc2s1 +COc1ccc(C(=O)NCCc2ccccc2)cc1C +COc1cc(NCC(=O)N2CCCCC2)cc(OC)c1 +COC(=O)CNC(=O)c1cccc(S(=O)(=O)Cc2ccccc2)c1 +COCC1CCCN(C(=O)NCCCc2c(C)noc2C)C1 +Cc1cnn(CCCNc2nc3c(cnn3-c3ccccc3)c(=O)[nH]2)c1 +Cc1onc(-c2cccc(F)c2)c1C(=O)Nc1ccc2c(c1)OCO2 +CC1(C)C(C2NCCc3c(F)cc(O)cc32)C1(C)C +N#Cc1c(N2CCOCC2)nsc1-c1ccccc1 +Cc1cc(C)c(CNc2nn3cc(C(C)(C)C)nc3s2)c(=O)[nH]1 +COc1cc(CNC(=O)CCc2ccccc2Br)ccn1 +Cc1cccc(C)c1NC(=O)N1CCN(C(C)C(=O)NC(C)C)CC1 +COc1ccc(C(=O)CNc2ccccc2C#N)cc1Cl +CC(=O)c1c(C)nc(C)nc1SCC(=O)N1CCC1 +c1ccc(-c2ncc(CN3CCCC(c4nccs4)C3)s2)nc1 +COCC(O)CN(C)C(=O)COc1cccc(Cl)c1 +CCS(=O)(=O)N1CCC(C(=O)NCc2ccccn2)CC1 +CC1C(=O)NCCN1C(=O)Nc1ccc(-n2ncc3ccccc32)cc1 +COCCOc1ccc(NC(=O)CC2CCCC2)cc1 +CN(C)C(=O)Cn1cc(C(=O)N(C)c2ccc(C(C)(C)C)cc2)nn1 +Cn1c(COc2ccccc2Cl)nnc1SCc1cnoc1 +C=CCn1c(-c2ccc(F)cc2)cn2cc(C(=O)NC)nc2c1=O +Cc1ccc(C(N)=O)c(OC(C)C(=O)NC(C)C)c1 +COc1cc(Br)cc(C)c1NC(=O)NC(C)C +Cc1cccnc1NC(=O)c1onc(-c2ccccc2)c1N +Cn1cc(Br)cc1C(=O)NC(C(N)=O)C(C)(C)C +N#CCOc1cccc(CC(=O)NCCc2cscn2)c1 +Nc1cc(=O)[nH]c(Cc2ccc(Br)cc2)n1 +COc1ccc2c(c1)C(C(=O)NC1CCCCNC1=O)CC(=O)N2 +O=C(Cn1cnc2ccccc21)NCc1cc(-c2ccco2)on1 +CC(C)(C)C(=O)Nc1ccccc1C(=O)NCCc1ccco1 +CCCN1C(=O)C(C)Oc2ccc(C(=O)C(C)N)cc21 +O=C1CN(C(=O)c2ccc(OCC3CCCO3)cc2)CCN1 +CCCCc1nnc2n1NC(c1ccc(F)cc1)CS2 +O=C(NCC1CCCCC1)C1CN(C(=O)COc2ccccc2F)C1 +O=C1CCN(C(=O)c2ccc3c(c2)NC(=O)CO3)CC1 +CCc1ccc(S(=O)(=O)N2CCOCC2C2CC2)s1 +COc1ccc(NC(=O)C(C)Sc2nccn2C)cc1 +CC1CCCN(C(=O)c2cncc(Br)c2)C1 +Cc1nc(N2CC3c4ccccc4OCC3(CO)C2)sc1C +O=C(Cn1cnc2ccccc2c1=O)NCc1ncc2c(n1)CCC2 +CCCCC(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +CC1CCCC(NC(=O)c2cc(C(N)=O)cs2)C1 +COc1cccc2c1N(Cc1nnc(C)n1C)CCC2 +Cc1ccn(-c2ccc(C(=O)NC3CCCCNC3=O)cc2)n1 +O=C(NCCCn1ccnn1)Nc1cc(F)ccc1N1CCCCC1 +CC(C)n1cc(C(=O)Nc2ccc3c(c2)ncn3C)c2ccccc21 +OC1(CNc2ncnc3[nH]cnc23)C2CC3CC(C2)CC1C3 +Cc1nc(CSc2ccccc2C(=O)NCc2ccccc2)no1 +O=C(c1cc(-n2cccn2)ccc1Cl)N1CCC2(CCCO2)CC1 +CC1CN(CC(=O)NC(C)c2ccc3c(c2)CCC3)CC(C)O1 +Cc1nonc1NC(=O)COc1ccc(F)cc1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)NCCCn1cccn1 +CCOC(=O)N1CCC(NC(=O)NCc2cc3ccccc3[nH]2)CC1 +COc1ccc(C2CC(O)=Nc3c2c(=O)nc(SC)n3C)cc1 +COC(C)C(=O)NCCNC(=O)c1ccccc1 +COCC(C)n1c(C)cc(C(=O)CSc2ccccc2F)c1C +CC(C)(C)OC(=O)CCn1cnc2c(cnn2-c2ccccc2)c1=O +CC1CC(C)CN(C(=O)c2cc(NC(=O)c3ccccc3)n(C)n2)C1 +Cc1cccc2c(CC(=O)N(C)CC3CC3)c[nH]c12 +CC(NC(=O)c1ccc(=O)n(C)n1)c1ccc(Cl)cc1Cl +COc1ccc(CNc2ncc(-c3cccc(OC)c3)n2C)cc1 +O=C(COC(=O)c1ccc2ccccc2n1)c1ccc(F)c(F)c1 +CCOc1ccc(F)c(C(=O)Nc2ccncc2C)c1F +Cc1nc(-c2ccc(NC(=O)c3c(C)noc3C(C)C)cc2)co1 +O=C(NCCc1nccs1)c1c[nH]nc1-c1ccccc1F +O=c1[nH]c2cc(-c3noc(C4CCC4)n3)ccc2n1C1CCCC1 +Cc1nc(N2CCCCCC2)sc1C(C)(C)O +Cc1nnc(SCC(=O)c2ccc(F)c(F)c2)n1C +COc1ccccc1C(C)NC(=O)Nn1cnc2ccccc21 +CC1CCCN(C(=O)CC(C)NC(=O)c2ccccc2)C1 +O=C(CCN1CCCC1=O)NC1CC1c1cccc(Cl)c1 +Cc1ncsc1CN1CCN(C(=O)c2c(F)cccc2F)CC1 +CC(=O)NC1CCCN(C(=O)CSc2ccccc2C)C1 +Cc1c(NCc2noc(C(C)C)n2)cccc1C(=O)NCCO +CCCCc1ccc(NC(=O)N2CCN(C(=O)N(C)C)CC2)cc1 +Cc1ccc(C)c(C(C)NC(=O)C2CCN(S(C)(=O)=O)CC2)c1 +COc1cc(C)ccc1CNC(=O)c1ccc(-n2ccnn2)cc1 +CSc1ncccc1C(=O)Nc1nc2ccccc2[nH]1 +COc1cccc(C(=O)Nc2ccc(SC)c(F)c2)c1F +CCCn1nc(-c2c(C)cc(C)cc2OC)cc(C#N)c1=O +CCNC(=O)C1(NC(=O)c2cc(Br)c[nH]2)CCCCC1 +COc1ccc(C2CCN(C(=O)c3cnccn3)C2)cc1 +NC(=O)c1csc(C(=O)Nc2cccc(Cn3cccn3)c2)c1 +CC(=O)Nc1ccc(C(=O)NCC2CN(CC(C)C)CCO2)cc1 +Cc1ccc(C#N)c(=O)n1-c1ccc(OC(C)C)cc1 +CCCCNC(=O)c1cc(S(N)(=O)=O)ccc1Br +CC(NC(=O)c1cc(=O)[nH]c2ccc(Br)cc12)C(N)=O +COc1ccc(N2CC(C(=O)Nc3nc(C)cs3)CC2=O)cc1 +CN(C(=O)c1cccc(-n2cc(Br)cn2)c1)C1CC1 +Cc1c(C(=O)NCCC(=O)N2CCCC2)oc2ccccc12 +CCc1nc(CSc2nc3cc(F)c(F)cc3[nH]2)no1 +Cc1ccc(-c2c(C)sc3nc(CO)cn23)c(C)c1 +O=C(NCc1cccnc1-n1ccnc1)NC(c1ccccc1)C1CC1 +CCOC(CC(=O)C1(O)CCCCC1)c1ccccc1 +O=C(NCc1ccc(NC(=O)C2CC2)cc1)c1ccccc1F +Cc1noc(C)c1CCc1nc(-c2cccnc2)no1 +Cc1nccn1Cc1cccc(CNC(=O)C2CCC(=O)N2)c1 +Cc1nnc2n1CCN(C(=O)c1cc(-c3cccc(Cl)c3)[nH]n1)C2 +CC(=O)NCC1CCCN(C(=O)Nc2ccc(F)c(F)c2)C1 +O=C(Nc1nnc(Cc2ccc(F)cc2)o1)c1ccc(Cl)cc1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)C(C)c1cccs1 +Cc1occc1CNC(=O)NC1CCN(c2ccccc2)C1 +COc1cc(CNC(=O)NC(C)Cc2ccc(O)cc2)ccn1 +C#CCOC(=O)c1ccc(-c2ccc(N)cc2C)o1 +Cc1noc(NC(=O)Cn2ncc(=O)c3ccccc32)n1 +Cc1cc2[nH]nc(N)c2c(=O)n1CCc1ccccc1 +CC(C)n1cnc2cc(Cc3c(O)n[nH]c3N)ccc21 +CCOCC(=O)Oc1cc2c(cc1C(C)=O)CCCC2 +COc1ccc(CN(C)C(=O)c2cccc(N)c2)cc1OC +O=S(=O)(c1cccc(Cl)c1)N1CCC(CO)CC1 +CCOC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +COCCNC(=O)CN1C(=O)COc2c(N)cccc21 +CCc1ccc(S(=O)(=O)N(C(C)=O)c2ccc(OC)cc2)cc1 +CC(C)N1CC(C(=O)Nc2ccc(Cl)c(F)c2)CC1=O +Cc1ccc2cc(C(=O)N3CCC(c4nncn4C)CC3)[nH]c2c1 +COC(C)c1nc(CNc2ccn(-c3ncccc3Cl)n2)cs1 +CCC(=O)NCC(=O)NCCc1cccc(Br)c1OC +CC(Nc1ccc(F)c(C#N)c1)c1ccc(O)cc1 +Cc1ccc(C)c(S(=O)(=O)NCCNC(=O)N(C)CC(F)F)c1 +O=C(NCC1COCc2nc3ccccc3n21)c1cnccn1 +Cc1sc2ncnc(NCCO)c2c1-c1ccc(Cl)cc1 +CC(=O)Nc1cccc(NCc2cnn(-c3ccccc3)c2)c1C +CN(Cc1cc(-c2ccccc2)no1)Cc1ccc(-c2cc[nH]n2)o1 +CCN(CC)C(=O)c1cccc(NC(=O)COc2cccc(C)c2)c1 +Cc1noc(CS(=O)(=O)c2nnc3ccc(C(F)(F)F)cn23)n1 +CNC(=O)NCC(=O)N(CCC1CCCCC1)CC(N)=O +CN(Cc1ccc(C(N)=O)cc1)C(=O)Nc1cn[nH]c1 +COc1ccc(S(=O)(=O)N(C)c2cccc(C#N)c2)c(C)c1C +O=S(=O)(c1ccccc1F)N1CCCC(O)C1 +O=C(c1ccc2c(c1)CCC2)N1CCN(CC2CCCO2)CC1 +COc1cccc(CN2CCOC(Cn3nc(C)nc3C)C2)c1 +CCc1ccc(NC(=O)c2cc3c(nc2N)CCC3)cc1 +O=C(CCn1ccc2ccccc21)Oc1cccc(NC(=O)C2CC2)c1 +CC(C)NC(=O)NC1CC1c1cccc(Cl)c1 +O=c1[nH]c(=O)n(CCO)nc1Cc1ccc(Cl)cc1 +COC(=O)c1ccc(C)c(NC(=O)c2cnc3n(c2=O)CCS3)c1 +CCOCCN(CC)C(=O)NCC1CN2CCCCC2CO1 +Cc1csc(CCCNC(=O)c2cc(S(N)(=O)=O)oc2C)n1 +COc1ncccc1CNC(=O)N1CCOC(C)(C)C1 +CC(=O)c1cccc(NS(=O)(=O)c2ccc(Cl)cc2)c1 +COCC(C)NC(=O)NCc1ccc(Cn2ccccc2=O)cc1 +CCc1c(C)noc1-c1cnc(C)nc1-c1cnc(C)cn1 +Cc1cc(NC(=O)C2CC(=O)N(C3CCC(C)CC3)C2)[nH]n1 +CCC(C(=O)NC(C)Cc1ccccc1C)c1c(C)noc1C +CNC(=O)CN(C1CCCCC1)S(=O)(=O)c1ccccc1 +Cc1cc(F)ccc1C(=O)N1CCN(C(=O)CO)CC1 +CCn1c(Cn2cncn2)nnc1C1CCN(c2cccnn2)CC1 +C#CCOc1ccc(C(=O)Nc2c(C)cc(C)cc2C)cc1 +CC(=O)c1c(C)[nH]c(C(=O)N2c3ccccc3CC2C)c1C +CCCCOC(=O)c1ccc(NC(=O)c2ccccn2)cc1 +Cc1nc(CCNC(=O)c2ccc(N3CCCC3=O)cc2)cs1 +Cc1n[nH]c(C(NC(=O)CSc2ccccc2)C(C)C)n1 +CC(C)CCN(C)C(=O)C1CC(=O)N(Cc2ccco2)C1 +Cc1cc(C(=O)NCC(=O)Nc2nccs2)c(C)s1 +Cc1cc(C(O)CCC(=O)NCC2CCCO2)ccc1F +CCCn1nnnc1CNC(C)c1ccc(Cl)cc1 +CSc1ccccc1NC(=O)Cc1ccc(F)cc1 +COC(=O)c1cc(-c2c(C)c(Cl)c(C)c(N)c2OC)n[nH]1 +Cc1ccc(C(=O)CCC(=O)Nc2ccc(N)c(C)n2)cc1 +COc1ccc(N)cc1S(=O)(=O)N1CCN(C)CC1 +Nc1cc(C(F)(F)F)ccc1NC(=O)c1ccncc1 +CNC(=O)Nc1ccc2nc(NS(C)(=O)=O)sc2c1 +CCC(C)n1nccc1NC(=O)CCC(=O)c1ccc(Cl)cc1 +O=C(Cc1noc2ccccc12)NCc1ccc(-n2cccn2)cc1 +O=C(CCn1ccccc1=O)N(Cc1cccnc1)CC1CCCO1 +CCc1onc(C)c1NC(=O)c1ccc2c(c1)OCO2 +CC1(C)COCCN1CC(=O)Nc1nccs1 +Cc1ccc(NC(=O)NC2CCCC2(C)C)cc1S(C)(=O)=O +CCOc1ccc(C(=O)NC2CCc3ccccc32)cc1OCC +Cc1c(CNc2ncnc3c2cnn3-c2ncccn2)cnn1C +CN(Cc1ccccn1)C(=O)c1cccc2[nH]ncc12 +CNC(=O)C1(C)CCCN(S(=O)(=O)c2cn(C)cn2)C1 +Cc1cnc(CCNC(=O)NCCC(=O)N(C)C)s1 +O=C1NC(c2cc(Cl)cc(Cl)c2)N2CCCCC12 +Cc1sc2nc(CSc3ncn[nH]3)[nH]c(=O)c2c1C +CC(O)c1c(-c2cccs2)nc2ccc(Br)cn12 +CC(C)N(C(=O)C1CCOC1)c1ccc(F)cc1Cl +CCC(OC)C(=O)Nc1cc(F)c(OC)c(F)c1 +CC(C)(C)CCNC(=O)CNC(=O)c1cccc(Br)c1 +COCCN1CC2=C(C1=O)C(c1ccc(OC)cc1)NC(=O)N2C +CC(=O)c1c[nH]cc(CNC(=O)OC(C)(C)C)c1=O +CNC(=O)CN(C)S(=O)(=O)c1cc(N)ccc1C +COc1ccc(OC)c(C(=O)Nc2cc(N3CCCCC3)ncn2)c1 +Nc1cc(C(F)(F)F)ccc1NCc1cc[nH]n1 +COC(=O)C(C)NC(=O)CCc1nc(-c2ccc(F)c(C)c2)no1 +Cc1nc(C(C)C)ncc1C(=O)N(C)Cc1cccc2cnccc12 +CCCn1c(=O)oc2cc(NC(=O)Nc3ccc(OC)cc3)ccc21 +COc1ccc(OC)c(CN(C)C(=O)c2sc(C)cc2OC)c1 +COc1ccc2c(c1)CCN(C(=O)C1CCCCn3nnnc31)CC2 +O=C(COc1ccccc1)NCC(O)c1ccc(F)c(F)c1 +Cc1c(NCc2ccc(C#N)cc2)cccc1S(=O)(=O)NC1CC1 +CCc1nc(C2CCCN(c3nnc(C)c(C)c3C#N)C2)no1 +CC(C)CC(NC(=O)Nc1ccn(C)n1)C(=O)OC(C)C +C=CCSc1nnc(COc2c(C)cccc2C)n1N +CCc1nc(C)c(C(=O)N2CCCC(c3noc(C)n3)C2)s1 +CS(=O)(=O)c1nccn1CC(=O)N1CCc2ccccc21 +CCc1ccc(-c2cc(C(=O)OC)nc(N(C)C)n2)cc1N +Cc1ccc(CCNC(=O)N(C)CC(C)c2nccs2)cn1 +C=CCOC(=O)C1=C(C)Nc2ncnn2C1c1ccc(C)cc1 +CCCNC(=O)c1ccc(NC(=O)c2ccc(=O)n(C)c2)cc1Cl +Cc1nc2c(cc1C(=O)NCC(C)N1CCOCC1)c(C)nn2C +Cc1cc(N)cc2sc(NC(=O)c3ccccc3)nc12 +COc1cc(NC(=O)NC(C)CCC2CCCC2)ccc1NC(C)=O +CN(C1CC1)S(=O)(=O)c1ccc(NC(=O)NC2CCCC2)cc1 +C#CCN1C(=O)CSc2nnc(COc3cccc(F)c3)n21 +CCCNC(=O)COC(=O)c1cc(SC)ccc1Cl +O=C(c1c[nH]c(=O)[nH]1)N(CC1CCOC1)C1CC1 +Cc1nnnn1-c1nc(-c2ccc(Cl)cc2)cc(C(F)(F)F)n1 +CCCC(NC(=O)Cn1cnc(C2CCC2)cc1=O)c1ccccc1 +CC(C)(C)c1ccc(CCC(=O)Nc2ncc(C(N)=O)s2)cc1 +CCOc1ccc(F)c(C(=O)NC2CCN(C)C2=O)c1F +N#Cc1nc(-c2cccc3ccccc23)oc1N1CCN(CCO)CC1 +Cc1ccc(C#N)c(=O)n1CC(=O)NC(C)c1ccccc1 +NS(=O)(=O)c1ccc(NC(=O)CCC2CCCCC2)cc1 +COc1ccccc1OCCn1c(=O)oc2ccc(C)cc21 +COc1cc(C)c(C(O)C(=O)N2CCNCC2)cc1C +Cc1ccc2ncc(C(=O)N(C)Cc3nc(-c4ccccc4)c[nH]3)n2c1 +CC(C)(C)C1CC(O)=Nc2c1cnn2Cc1ccco1 +O=C(C1CC1c1cccnc1)N1CCCC1Cn1cccn1 +CCn1nc(C)c(CCNc2cc(OC)ncn2)c1C +CCC(Cc1ccc2c(c1)NCCO2)N1CCOCC1 +CCn1cc(S(=O)(=O)NCc2ccc(C)cc2)c2cccnc21 +O=C(OC1CCCCC1)c1sccc1-n1cnnn1 +Cc1nnc(C(=O)NCCOc2ccc(C(F)(F)F)cc2)s1 +C=CCn1c(SCc2cccnc2)nnc1-c1ccncc1 +COC(=O)C(C)n1c(CCO)nc2ccc(F)c(F)c21 +O=C(CN1C(=O)COc2ccccc21)Nc1nc2ccccc2[nH]1 +CCCC(C)NC(=O)C1CCCN(C(=O)NC2CCC(O)CC2)C1 +COc1ccc(CNC(=O)c2ccc(C)c(F)c2)c(OC)c1 +COc1cc2nc(C#N)n(C3CCCC3)c2cc1OC +CCOc1cc2c(cc1O)C(Cn1cnnn1)NCC2 +CC(C)NC(=O)CN(C)C(=O)CNc1ccccc1Cl +COC(=O)CCN(Cc1cnc2nc(C)cc(C)n12)C(C)C +O=C1CCC(C(=O)Nc2cccc(-c3nc4ccccc4[nH]3)c2)N1 +COc1ccc(C(=O)CSc2nncs2)c(OC)c1 +Cc1c(NC(=O)c2ccc(N3CCCC3)c(F)c2)cccc1C(N)=O +CCCc1nc(C(=O)N2CCCC(OC)C2)cs1 +O=C(NC1CCCC1)c1cc(Br)ccn1 +COC1CCCC(OC(=O)CCNC(=O)C(C)(C)C)C1 +CC(C)(C)OC(=O)N1CCCC(NC(=O)c2cccnc2)C1 +CNC(=O)c1nn(-c2ccc(OC)c(OC)c2)c(OC)cc1=O +Cc1ccc(-c2noc(-c3ccccc3NC(=O)C(C)C)n2)cn1 +CC(C)C(=O)N1CCC(C(=O)OCC2CC=CCC2C)CC1 +CCC(=O)Nc1cccc(NC(=O)c2cc(OC)c(OC)cc2C)c1 +CN(C)c1oc(COc2ccc(Br)cc2)nc1C#N +O=C1Cc2cc(-c3csc(-c4ccsc4)n3)ccc2N1 +Fc1ccccc1CNC1CCOc2ccc(Cl)cc21 +Cc1ccccc1-n1nccc1NC(=O)Cc1ccc[nH]1 +O=C(CC1CCN(C(=O)Nc2ccc(F)cc2)CC1)N1CCCCC1 +CC(=O)N(C)C1CCN(c2ncnc3c2cnn3CCO)CC1 +NC(=O)c1n[nH]c2ccc(NC(=O)CCc3cccc(Cl)c3)cc12 +O=C(CSc1ncc2ccccn12)NCC(F)(F)F +Cc1cnc(C(=O)Nc2cccc(C#Cc3ccccc3)c2)cn1 +O=C(Nc1cccnc1)c1ccc(Cl)c(Cl)c1 +CCC(C)NS(=O)(=O)c1ccc(C(=O)Nc2ccccc2O)cc1 +Cc1nccn1-c1ncccc1NC(=O)Cc1ccc2c(c1)CCCC2 +CCCCN(C)C(=O)c1ccc(N2CCOC2=O)cc1 +COC(=O)c1cc(-c2ccc(N)cc2)nc(N2CCCC(C)C2)n1 +CCC(C)C(NC(=O)CNC(=O)C(C)(C)C)C(N)=O +O=C(c1cccnc1N1CCOCC1)N1CC2CC3CC(C2)CC1C3 +CSc1nnc(C)c2c(C)n(-c3ccc(C)cc3)nc12 +CC(C)(NC(=O)C1CN(Cc2ccccc2)CCO1)c1nccs1 +O=C(c1ccc(-c2ccccc2)[nH]c1=O)N1CCN(CC2CC2)CC1 +CC(NC(=O)c1ccc2c(c1)NC(=O)CS2)c1ccc(F)c(F)c1 +CCOCC1CCN(C(=O)C2CCN(C(=O)C(C)(C)C)CC2)CC1 +CCN(CC)C(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +CCc1nnc(NC(=O)C2(c3ccccc3)CCCC2)s1 +OCCNc1nc(N2CCCCC2)nc(N2CCCCC2)n1 +Cc1nsc(NC(=O)c2ccccc2Cl)n1 +CCCCNc1nc2c(c(=O)[nH]c(=O)n2C)n1C +Cc1ncc(C(=O)NC23CC4CC(CC(C4)C2)C3)c(N)n1 +CN(C(=O)CS(=O)(=O)c1ccc(Cl)cc1)C1(C#N)CCC1 +CCn1c(C)cc(C(=O)Cn2cc(Br)cn2)c1C +CCS(=O)(=O)n1nc(-c2ccc(Cl)cc2)nc1SC +CC1CC(=O)Nc2cc(Br)cc(C(C)C)c2O1 +CCCn1ccnc(NCc2nccs2)c1=O +Cc1cc(C)nc(-n2nc(C)cc2Nc2ccccc2)n1 +COc1cccc(C2=Nn3c(nnc3-c3cccnc3)SC2)c1 +CCN1CC(C(=O)N2CCN(c3cccc(F)c3C#N)CC2)CC1=O +CC(C)(C)OC(=O)N1CCCC(c2cc(F)ccc2N)C1 +Cc1ccc(Cn2cccc(S(=O)(=O)N3CCCC3)c2=O)cc1 +COc1ccc(C(C)NS(=O)(=O)N(C)C)cc1F +CCCN(CC(=O)NC)C(=O)c1cc(Br)cn1C(C)C +O=C(Oc1ccccc1)N1CCCN(C(=O)c2ccccc2)CC1 +O=C(NC1CCc2cc(F)ccc21)c1ccccc1F +CC(=O)Nc1cccc(NC(=O)COc2cccc(NC(C)=O)c2)c1 +Cc1cc2c(c(=O)[nH]1)C(c1ccc3c(c1)OCO3)CC(=O)O2 +C=CCN(C(=O)CNc1ccccc1)C1CCCC1 +CCCCCn1c(N2CCCC2)nc2c1c(=O)n(C)c(=O)n2C +CN(Cc1cccc(C#N)c1)S(=O)(=O)c1ccccc1F +OCC(O)C1NCCc2ccc(O)c(Br)c21 +O=C(OCC(=O)N1CCCC1)c1cnc(C2CCCO2)s1 +CC(C)Cn1nnnc1SC(C(=O)N1CCCC(C)C1)C(C)C +CCC(C)NC(=O)c1sc2nc3n(c(=O)c2c1C)CCCCC3 +COc1ccc(Nc2nc(C)cc(C)n2)cc1OC +O=C(NCc1ncc(-c2ccccc2)[nH]1)C1CCOC1 +CCn1c(SCN2CCCCC2=O)nnc1-c1ccc(F)cc1 +Cc1ccnc(CC(C)N(C)C(=O)c2ccc3[nH]c(C)nc3c2)c1 +COc1ccc(C(=O)c2c(OC)cccc2OC)cc1N +CC(C)NC(=O)CSc1nc(-c2ccccc2)cc(=O)[nH]1 +c1csc(CN(Cc2ccc3c(c2)OCO3)CC2CCCO2)c1 +O=C(NCC(CO)c1ccccc1)c1ccc(Cl)cn1 +CNc1ncnc(Nc2ccccc2C(=O)OC)c1N +C=CCn1nnnc1SC(C)c1nc(Cc2ccc(F)cc2)no1 +COCCCNC(=O)c1cccc(NC(=O)c2ccccc2Cl)c1 +CCOC(=O)CNc1nc(C)c(Br)c2ccccc12 +CCC1CCCN(c2nn3c(=O)cc(C)nc3s2)C1 +CCOCCC(=O)N1CCN(C(=O)c2ccc(O)cc2)CC1 +CC(Oc1ccc(F)cc1)c1nnc(Sc2ccc(C#N)cn2)o1 +Fc1cc(Br)cc2c1C(c1cc[nH]n1)NCC2 +CCOc1ccc(C(=O)NCc2cccc(O)c2)cc1 +O=C(c1cc2c([nH]c1=O)CCCC2)N1CCCc2cccc(F)c21 +CCCCOC(=O)c1cccc(-n2cc(CO)nn2)c1 +Cc1cc(C(=O)NC2CCCNC2=O)sc1C +COc1ccc(OCCN(C)C(=O)c2ccccc2OC)cc1 +CCN1CCOCC12CCN(C(=O)c1ccsc1)CC2 +O=C(Nc1cc(N2CCCC2)ncn1)c1ccc2ccccc2n1 +Cc1nc(CNC(=O)C(C)(C)c2ccc(Cl)cc2)c(C)s1 +Cc1ccc(C(=O)NC2CCN(C(=O)Nc3ccccn3)CC2)s1 +CC(=O)c1nnc(-c2ccc(C)cc2)n1Nc1ccccc1 +CCS(=O)(=O)NC(C)C12CC3CC(CC(C3)C1)C2 +O=C(NCc1ccnc(-n2cccn2)c1)c1ccccc1C(F)(F)F +Cn1cc(NC(=O)N2CC3CCCCC32c2ccccc2)cn1 +Cc1cc2nnc(SCC(=O)N(C)CCC#N)n2c2ccccc12 +O=S(=O)(NCc1ccoc1)c1ccc2c(c1)OCCO2 +C=CCNC(=O)c1cnn2c(C(F)F)cc(-c3ccccc3)nc12 +Cc1ccccc1OCC#CCNS(=O)(=O)N(C)C +CN(Cc1cc(C#CCO)cs1)C(=O)c1cc[nH]n1 +O=C(CCC1CCCCC1)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(CC(O)c1ccco1)NC(=O)c1ccn(C2CCCC2)n1 +Cc1cc(=O)oc(C)c1C(=O)OC1CC(C)OC1=O +Cc1ccc(C(=O)N(CCC(N)=O)Cc2ccccc2)cn1 +CC(C)C(CNC(=O)c1ccc2c(c1)CCC(=O)N2)N1CCOCC1 +CN(Cc1ccccc1Cl)C(=O)NCC(C)(C)C(N)=O +CSc1ccc(CN(C)C(=O)CNC(=O)C(C)(C)C)cc1 +CC(NC(=O)c1cnccn1)c1ccc(Br)cc1 +COc1ccccc1CNS(=O)(=O)Cc1ccccc1C +CC(C)C(NC(N)=O)C(=O)Nc1ccc(OC(F)F)cc1 +COC(=O)C(O)c1ccc2c(c1)N(C)C(=O)CCO2 +COc1cc(C(C)=O)ccc1OS(=O)(=O)c1c(C)noc1C +CC(CNC(=O)N1CCCN(CC(F)F)CC1)c1ccsc1 +Cc1cn2nc(N3CCN(c4nccs4)C(C)C3)sc2n1 +Cc1nc(NC(=O)c2c(O)cc(F)cc2F)sc1C +CC1CCN(C(=O)C2CCN(c3ccc(Cl)cc3)C2=O)CC1 +CCCNC(=O)c1cccc(C(=O)Nc2ccccc2OC(F)F)c1 +O=C(CNC(=O)c1ccc(F)cc1)Nc1ccccn1 +CCc1ccc(CN(C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1 +Cc1nc2sccc2c(=O)n1NC(=O)c1cc(F)ccc1F +CC(NC(=O)CC(C)(C)C)c1ccccc1NS(C)(=O)=O +CN(Cc1ccc(F)c(F)c1)Cc1ccnc(N(C)C)n1 +O=C(NCc1cccnc1)N1CCOCC1C1CC1 +CCc1nc(C2CCCN(C(=O)c3ncoc3C(C)C)C2)no1 +O=C(Cc1ccccc1Cl)NCC(c1ccco1)N1CCOCC1 +Cn1nc(CC(=O)NCCc2ccc(O)cc2)c2ccccc2c1=O +CN(C)C(=O)c1ccc(S(N)(=O)=O)cc1OC1CC1 +CC(=O)Nc1cccc(NCc2nc3ccccc3o2)c1C +CCOc1ccc(NC(=O)c2ccc(C#N)cc2)cc1OC +CNC(=O)c1ccc(CSc2cc(C#N)ccn2)cc1 +c1ccc2nn(Sn3nc4ccccc4n3)nc2c1 +CCc1noc(C)c1C(=O)N1CC2CCC(C1)N(CC1CCC1)C2=O +CCN(CC(=O)Nc1ccc2c(c1)OCCO2)C(=O)C1CCCCC1 +CC(C)c1cc(C(=O)Nc2ccc3c(c2)CCC(=O)N3)n[nH]1 +CC(C(=O)Nc1ccc2c(c1)OCO2)c1cccs1 +Cc1cc(CNC(=O)Nc2cc(F)cc(N3CCCC3)c2)no1 +Cc1cc(NCc2csc(-c3ncccn3)n2)n2nccc2n1 +COc1ccccc1NC(=O)Nc1c(C)nc2ccc(C)cn2c1=O +CC(C)(C(=O)NC1CC1)c1ccc(Br)cc1 +COc1ccc2c(c1)OCC(C(=O)Nc1ccc(O)cc1)C2 +CC(C)(C)c1cn2nc(NCCC(=O)N3CCOCC3)sc2n1 +Cc1c(C(=O)Nc2ccc(-n3cnnn3)cc2)oc2c(F)cccc12 +Cn1cc(C2(C)CN(C(=O)Nc3ccc4c(c3)COC4)CCO2)cn1 +O=C(Cc1ccccc1)N1CCc2ncnc(-c3ccncc3)c2CC1 +CC(C)c1ccc(C(=O)N2CCC(N(C)S(C)(=O)=O)CC2)cc1 +O=C1CCCN1CCC1CN(Cc2cncs2)c2ccccc21 +COCCNS(=O)(=O)c1cc(OC)c(OC)cc1C +CN(C)C(=O)N1CCN(C(=O)NCCN(C)c2ccccc2)CC1 +CCOC(=O)C1C(=O)OC(C)(C)C1C(C)C(=O)c1ccc(C)cc1 +CCc1cccc(C)c1NC(=O)C1CCN(C(=O)C(C)(C)C)CC1 +CCN(CCO)C(=O)C1CC(=O)N(Cc2ccccc2)C1 +N#Cc1cn(C2OC(CO)C(O)C2O)c2ncnc(N)c12 +COc1ccccc1-n1ncnc1-c1cc(C2CC2)n[nH]1 +NC(C(=O)NCc1ccccn1)c1ccc(O)cc1 +CC(C)NC(=O)Nc1ccccc1NC(=O)c1ccc(C(N)=O)cc1 +COc1ccccc1CN(C(=O)c1cccc(C#N)c1)C1CC1 +O=C(c1ccccc1Cl)N1CCC(C(=O)N2CCOCC2)CC1 +O=C(CSc1nnnn1-c1ccccc1F)N1CCOCC1 +CCc1cc(Oc2cccnc2)nc(-c2ccccn2)n1 +CNC(=O)c1ccc(OC2CCN(C(=O)OC(C)(C)C)CC2)cc1 +COCCCNC(=O)C1(C)Oc2ccccc2NC1=O +CCCOc1ccc2sc(NC(=O)OC)nc2c1 +O=C(NCc1noc(-c2cccs2)n1)C1COCCO1 +Cc1cc(=O)n2nc(N3CCC(C(=O)N4CCCC4)CC3)sc2n1 +N#Cc1cc(-c2ccc(C(F)(F)F)cc2)c[nH]c1=O +COc1ccc(F)cc1NC(=O)C1COc2ccccc2O1 +O=C(CC1CCCN1S(=O)(=O)c1cccnc1)c1ccc(F)cc1 +O=C1CC2(CCN(Cc3cnc[nH]3)CC2)CN1Cc1ccccc1 +CC1Oc2ccccc2N(Cc2ccc(F)cc2)C1=O +Cc1ccc(NC(=O)CN(C)C(=O)c2cn3ccc(C)cc3n2)cc1 +Cc1occc1C(=O)Nc1cccc(S(C)(=O)=O)c1 +CC(=O)Nc1ccc(CNc2cc(F)ccc2F)cc1 +Cc1ccc(CNc2ncnc(Nc3ccc(C)cn3)c2N)cc1 +CCOc1ccccc1NC(=O)c1cccc2ccc(C)nc12 +Cn1ncc2c1CCCC2NC(=O)Nc1ccc2c(c1)OCO2 +CC(C)C(=O)Nc1ccc2c(c1)C1(CCOCC1)CN2C(=O)N(C)C +COCc1cccc(C(=O)Nc2ccccc2C(=O)N(C)C)c1 +Cc1nn(C)c2nc(NC3CCCNC3=O)sc12 +C#Cc1cccc(NC(=O)NCc2ccc(OCCO)c(OC)c2)c1 +CC(=O)Nc1ccccc1OS(=O)(=O)c1c(C)noc1C +CN(CCCOc1ccc(F)cc1)C(=O)NCc1ncn(C)n1 +Cn1cc(-c2ccc(C(=O)N3CCCC3)cc2)cn1 +CC(OC(=O)c1nc(C2CC2)n(-c2ccccc2)n1)C1CC1 +COc1ccccc1-n1cc(C(=O)N2CCOc3ccccc32)cn1 +CC(C)CC1(CNC(=O)c2cnn(C)c2)CCCC1 +Cc1nc(CN(C)C(=O)Cn2ccc(N)n2)cs1 +O=C(Nc1ccc2c(c1)COC2)c1c[nH]cc1-c1ccc(F)cc1 +O=C(Nc1ccc(NCCCO)nc1)c1cccnc1 +CN(Cc1nccs1)Cc1cccc2c1OC(C)(C)C2 +Cc1cc(NC(=O)CCn2nc(-c3ccccc3)oc2=O)no1 +CCOCCSc1nnc(-c2ccc(OC)cc2)n1C +CCOC(=O)CN(C(=O)C1CC(=O)N(CC)C1)c1ccc(F)cc1 +CCOC(=O)CN(C)C(=O)CSc1ccc(F)cc1 +Cc1cc(C(=O)COc2cccc(C#N)c2)c(C)n1CC(F)(F)F +CCOc1ccc(C(=O)Nc2ccccc2C(=O)N2CCCC2)cc1 +O=C(CC1C=CCC1)NCc1ccc2c(c1)OCO2 +Cc1ccc(C(=O)N2CCC(Cn3cc(C(C)O)nn3)CC2)cn1 +COc1ccc(OC)c(C(C)(NCC(F)(F)F)C(N)=O)c1 +Cc1ccc(C(=O)OCCNC(=O)c2ccncc2)cc1 +O=C(CNC(=O)c1ccccc1)NCc1ccccc1F +Cc1nc2cc(OCC3CCOCC3)c(N)cc2s1 +Cc1cc(C)n2nc(C)c(C(=O)NCc3nc4ccccc4[nH]3)c2n1 +CC(C)CCC(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1 +Cc1ocnc1C(=O)NCCc1c[nH]c2ccccc12 +Cc1cc(Cl)c(C(=O)NCc2ccnc(-n3ccnc3)c2)cc1C +COC(=O)C(O)c1cc(Cl)c2c(c1)OCCO2 +CN(CC(=O)N(Cc1ccoc1)Cc1cccs1)S(C)(=O)=O +N#Cc1ccc(NC(=O)NCc2cccc(C(N)=O)c2)cc1Cl +Cn1cc(N2C(=O)CC3C2CCN3C(=O)CO)cn1 +Cc1cccc(CCCOC(=O)C2CCc3cn[nH]c3C2)n1 +OCc1nnn(CC(O)CO)c1-c1ccc(F)c(F)c1 +CC(C)(C)c1ccc(C(=O)Nc2cnc3scnn3c2=O)cc1 +O=C(OC(C(=O)NC1CC1)c1ccccc1)c1ccc(O)cc1 +NC(=O)c1c(NC(=O)CSc2ccccc2N)sc2c1CCC2 +CCCCC(=O)NCCCn1ncc2ccc(C)cc21 +Cc1cc(NC(=O)C2CCN(C(=O)c3cccnc3)CC2)no1 +CCc1cccc(NC(=O)CNC(=O)c2ccc(F)nc2)c1 +O=C(NCc1cccnc1)NC1(c2cccc(Br)c2)CC1 +Cc1cccc(NC(=O)c2ccc(S(C)=O)cc2)c1C(N)=O +Cc1ccc(C2NCCc3ccc4c(c32)OCCO4)cn1 +Cc1ccc(CCNC(=O)C2CCC(=O)N2Cc2ccc(C)o2)cc1 +CC1CCN(C(=O)C2CCCCN2C(=O)c2ccoc2)CC1 +O=C(NCCC(=O)N1CCCc2ccc(F)cc21)c1ccccc1 +CCC(O)Cn1ccc(-c2cccc(-c3cnn(C)c3)c2)n1 +N#Cc1cccnc1NCc1ccc(C(F)(F)F)cc1 +NC(=O)c1ccc(NC(=O)NC(C2CC2)C2CC2)cc1 +Cc1cc(C)c2c(n1)nn1c(NCCN3CCOCC3)cc(C)nc21 +Cc1c2ncn(CC(=O)Nc3ccc(F)cc3)c(=O)c2nn1C +Cc1[nH]ncc1CCCNC(=O)N1CCN(Cc2cccs2)CC1 +CC(C)CNC(=O)C1(NC(=O)c2cnn3c2OCCC3)CCCC1 +Cc1ccnc(SCC(=O)NC2CCCCCC2)n1 +O=C(Cc1cc(Cl)c2c(c1)OCCO2)N1CCCC(O)C1 +O=C(NCC1CCCO1)c1ccc(COc2ccccc2Cl)o1 +Cc1sc2nc(N)nn2c1-c1ccc2c(c1)n(C)c(=O)n2C +COc1cc(C)c(Cl)c(C)c1-c1cc(N)nc(C)n1 +Cc1nccc(CNCc2ccc(O)c(Br)c2)n1 +O=C(c1csc(C2CC2)n1)N1CCC(c2nnc3n2CCC3)CC1 +CC(c1ccccc1F)N(C)CCc1nc2ccccc2c(=O)[nH]1 +CC(OC(=O)C1=NC=CC1)C(=O)Nc1ccc(F)cc1 +COc1ccc(CNC(=O)c2cnns2)cc1OC(F)F +Cc1cc2nc(C3CCCCN3C(=O)c3ccccn3)[nH]c2cc1C +CCOC(=O)CN(C(=O)c1cc(C)nn1C)c1ccc(F)cc1 +COc1ccc(OCCC(=O)Nc2ccc3c(c2)oc(=O)n3C)cc1 +O=C(CCCNC(=O)c1ccc(F)cc1)OC1CCCCC1 +COc1ccccc1CC(=O)NCC(=O)NC(C)(C)C +Cn1c(C(F)(F)F)nc2cc(OC(F)(F)F)ccc21 +O=C(Nc1ccc(-n2cncn2)nc1)C1CC(=O)N(C2CC2)C1 +COC(=O)C1CC1C(=O)NCC(O)c1c(F)cccc1F +COc1ccccc1OCCNC(=O)c1cccc(Cl)c1 +CCOc1cc(CN2CCNC(=O)C2c2ccccc2)ccc1OC +O=C(NCc1nnc2ccccn12)c1ccc(F)c(F)c1 +COc1ccc(NC(=O)c2cc3cccc(OC)c3o2)cn1 +Cc1ccccc1-c1cc(NC(=O)c2ccc3nncn3c2)n(C)n1 +COCCNc1ncnc(NC2CCCCCC2)c1N +CC(=O)c1c[nH]c(C(=O)N(C)C2CCCCCC2)c1 +COc1cccc(C(=O)N(C)c2cccc3ncccc23)c1 +CCC(C#N)CC(=O)Nc1ccc(C(F)(F)F)cc1 +CCOc1ccc(OC(=O)Cc2csc(C)n2)cc1 +CCCCc1nc(C)c(C(=O)NC(C)c2ccncc2)s1 +COc1ccc2c(=O)c(Br)c[nH]c2c1 +Cc1cc(CN(C)c2cc(Cl)ccc2C#N)no1 +CC(C)(C)n1ncn(Cc2noc(C3CCOCC3)n2)c1=O +CCC(Oc1ccc2c(c1)CCC2)C(=O)Nc1nc(C)cs1 +CC1c2ccsc2CCN1C(=O)C1CCCN(c2ncccn2)C1 +COC(=O)CCN(C)S(=O)(=O)c1ccc(F)cc1C +O=C(NC1CCCc2[nH]c(=O)ccc21)c1ccncc1 +CCOc1cc(-c2cc(C(=O)OC)[nH]n2)c(OCC)cc1Cl +CC(CO)NC(=O)c1cc2c(F)cc(Br)cc2[nH]1 +CCCCNC(=O)C1CCCN(C(=O)CNC(=O)NC)C1 +NS(=O)(=O)CCNC(=O)c1cc(-c2ccccc2)[nH]n1 +Cc1noc(N)c1C(=O)OCC(=O)OC(C)(C)C +CCCNS(=O)(=O)c1cc(C)c(OC)c(N)c1C +NC(=O)c1cc(Cl)ccc1NC(=O)C1CC1c1ccccc1Cl +COc1cc(C(=O)NCc2cccc(C)c2)cc(OC)c1OC +CC(=O)c1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1 +CCSc1ccc(Cl)cc1NC(=O)c1ccc(C(N)=O)cc1 +CNC(=O)N1CCc2ccc(C(=O)NC(C)(C)C)cc21 +CC(C)(C)OC(=O)N1CCNC(c2cccc(O)c2)C1 +O=C1CN(C(=O)Cc2csc(-c3cccc(F)c3)n2)CCN1 +CCNc1nc(-c2csc(N(C)C)n2)cs1 +O=C1CCc2cc(C(=O)NCCc3nc4ccccc4[nH]3)ccc2N1 +CCC(C)N(Cc1ccccc1)C(=O)c1cnccn1 +Cn1nnnc1SCC(=O)Nc1cc(Cl)ccc1F +NC(=O)c1ccsc1NC(=O)c1cccc(Br)c1 +O=C(CCOc1ccccc1)N1CCC(c2nnc3n2CCC3)CC1 +COC(=O)c1cccc(CNc2ccc(C(C)=O)cc2)c1 +Fc1ccc(-c2nnn(Cc3noc(-c4ccco4)n3)n2)cc1 +Cc1cn(-c2ccccc2Cl)nc1C(=O)OCCC(=O)N(C)C +CCN(CC)C(=O)CSc1nc(C)cc(-c2cccs2)c1C#N +CCn1cnnc1SCC(=O)c1[nH]c(C)c(C(=O)OC)c1C +COc1nc2ccccc2nc1CCc1nc(C2CCOC2)no1 +Cn1cc(S(=O)(=O)N2CCC(NC(=O)C(C)(C)C)CC2)cn1 +CC1CCCC(CNC(=O)NCCc2cnn(C)c2)C1 +CN(Cc1cnn(C)c1)C(=O)CN1CCOC(c2nccs2)C1 +CC(C)S(=O)(=O)N1CCCC1c1nncn1C +CC(=O)Nc1nc(C(=O)NCCC2=CCCCC2)cs1 +Cc1c(C)c(C)c(S(=O)(=O)N(C)CCO)c(C)c1C +CS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1 +Cc1ccc(C(=O)N2CCN(C(=O)c3ccc(C)cc3)C(C)C2)cc1 +Cc1ccc2c(C)c(C(=O)N3CCOCC(CO)C3)oc2c1 +Cc1ccc(C(=O)N2CCC(CC(=O)N3CCOCC3)CC2)c(O)c1 +O=C(c1ccsc1)N(Cc1cccnc1)c1ccc(F)cc1 +Cc1n[nH]cc1CNS(=O)(=O)c1ccccc1F +Cc1ccc(NC(=O)c2cc(-c3ccccn3)[nH]n2)cc1F +CNC(=O)Cn1ccc2ccc(NC(=O)NC(C)CCCO)cc21 +CC(=O)NCC(=O)N1CCCC(CCc2ccccc2F)C1 +O=C(NC1CCCCC1)N1CCN(Cc2cnc3ccccn23)CC1 +Cn1nnnc1SCC(=O)Nc1nc2c(s1)C(=O)CCC2 +COc1cc(N2CCC3C(CCC(=O)N3CCCO)C2)ncn1 +CC1Cc2ccc(F)cc2CN1C(=O)CCOC1CCOCC1 +O=C(NCc1ccc(F)cc1)NCC1(O)CCc2ccccc21 +COCCNC(=O)Cn1nnc(-c2ccccc2Br)n1 +CCOC(=O)c1sc(SC)c2c1CCCC2=O +COCc1cccc(CNC(=O)CN2c3ccccc3CC2C)c1 +O=C(NC1(c2ccc(F)cc2)CCCC1)c1ccc(=O)[nH]c1 +Cn1nncc1CN1CCC(Oc2ccc(Cl)c(Cl)c2)C1 +Cc1c(O)cc(O)c2c1OC(c1ccccc1)CC2=O +N#CCn1nc(-c2ccc3c(c2)OCO3)c2c1CCNC2 +CCOc1nn(CC)cc1-c1nnc(SCC)n1C +CN(C)C(=O)c1cccc(OC(=O)CCc2cccc(Cl)c2)c1 +COc1ccc(CCNc2ncnc3[nH]cnc23)cc1OC +CN(CC(=O)NCc1ccnc(OC(C)(C)C)c1)c1ccccc1 +O=C(Nc1ccc(N2CCCC2=O)c(Cl)c1)c1ccncc1 +CN(C)C(=O)COc1cc(C(=O)Nc2cccc(C(N)=O)c2)nn1C +O=C(CN1C(=O)CSc2ccccc21)Nc1ccc(Cl)cc1 +CN(C)C(=O)Cc1ccc(NCc2noc(-c3ccoc3)n2)cc1 +CCOc1ccccc1NCC(=O)c1ccc2c(c1)OCCO2 +N#Cc1ccc(CCC(=O)Nc2nc3c(s2)CCC3)cc1 +Cc1nc2ccccc2n1CCNC(=O)CCOc1ccccc1F +O=C(Cn1nnc(-c2ccccc2F)n1)NCc1ccc(F)cc1 +O=C(NC1CC1)c1cn(Cc2ccccc2Cl)nn1 +Fc1cccc(CN2CCc3nnc(-c4ccccc4)n3CC2)c1F +O=C(NCc1ccccc1)c1ccc(Oc2ncccn2)cc1 +O=c1ccn(Cc2ccn(C3CCCC3)n2)c2ccsc12 +Cc1nn(C)c(C(=O)N2CCCN(c3ccccc3)CC2)c1Cl +CC(=O)c1cccc(OC(C)C(=O)Nc2ccc(F)c(C#N)c2)c1 +O=S(=O)(C1CC1)N1CC(c2nc(-c3ncccn3)no2)C1 +CCC(C)C(=O)NCCC(=O)Nc1cccc(C)n1 +CCOC(=O)C(C)NS(=O)(=O)N(C)C(C)C +COc1cc(-c2ncccc2C(=O)N2CCCC2)cc(OC)c1OC +Cc1ccc(C(=O)N2CCOCC2)cc1NCc1ccccc1 +C=CCn1c(SCCn2nc(C)cc2C)nnc1-c1ccoc1C +COc1cc(Cc2cnoc2N)cc(OC)c1OC +CCC(CO)NC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +COc1ccc(C(=O)Nc2nc3c(s2)CN(C(C)C)CC3)cc1 +COC(=O)CN(C(=O)CSc1ccccc1C)C(C)C +COC(=O)C(C)n1c(C(C)C)nc2cc(N)ccc21 +COc1cccc2cc(C(=O)NCC(O)c3ccsc3)c(=O)oc12 +CCOCC(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +CC1CCCC(C)N1C(=O)c1cn(C)c2cccc(N)c2c1=O +Cc1cc(C)n(CC2CCN(C(=O)c3cnc4ccccn34)CC2)n1 +NS(=O)(=O)N1CCc2sccc2C1c1ccccc1 +Cc1ccc(CN(Cc2ccco2)C(=O)CNC(=O)NC2CC2)s1 +Cc1cccc(Cc2cnc(NC(=O)Cc3c(C)n[nH]c3C)s2)c1 +Cc1nc(OCC(=O)N2CCOCC2)c2ccccc2n1 +C=CCNC(=O)c1ccn(COc2ccc(Br)cc2)n1 +Cc1nc2cc(-c3nccn3C)nn2c(N2CCCC(O)C2)c1C +CN(CC(=O)Nc1ccc(Cl)c(Cl)c1)C(=O)Cn1cnnn1 +CCN(CC(O)c1ccc(C)cc1)C(=O)c1ccc(=O)n(CC)n1 +Cc1nc(NCc2ccccn2)c2c(n1)c(C)nn2C +CCCN(C)c1ccc(C(=O)NCC2CN3CCCC3CO2)cc1 +CC(C)COCCC(=O)N1Cc2ccccc2CC1C(N)=O +COCc1noc(C(C)Nc2cnn(-c3cccc(Cl)c3)c2C)n1 +CC(C)(C)N1CC(C(=O)NCc2cccnc2)CC1=O +CCC1CCC(N(C)C(=O)CNC(=O)C2CCCC2)CC1 +COCCN(CCC#N)C(=O)c1ccc(C)c(O)c1 +CCN1C(=O)C(C)Oc2ccc(S(=O)(=O)NC)cc21 +Cc1nc2ccccc2nc1NCCCN1CCOCC1 +CC(CC1CCCC1)C(=O)Nc1cccc(C(=O)N2CCCC2)c1 +CC(CO)(CO)NC(=O)CN1CCN(c2cccc(Cl)c2)C1=O +CC(=O)N1CCN(CC(=O)c2c(C)c(C)cc(C)c2C)CC1 +O=C(Nc1c[nH]ccc1=O)c1ccc(Cn2cncn2)cc1 +COC(=O)c1cc(NS(=O)(=O)N(C)C)cc(C(=O)OC)c1 +CCn1cc(C(=O)NCC2CCCO2)c2n[nH]c(=O)c-2c1 +Cc1csc(=O)n1CCC(=O)N1c2ccccc2N(C)CCC1C +NC(=O)N1CCCC(C(=O)Nc2ccc(OCC(F)(F)F)cc2)C1 +Cc1cccc(C)c1OCCNC(=O)CSc1nnc(C)n1N +O=S(Cc1nnnn1C1CC1)c1ccc(C(F)(F)F)cn1 +CCCCn1c(=O)n(CC)c(=O)c2c1nc(NCCO)n2C +CC(C)(NS(C)(=O)=O)c1nc(-c2ccncc2)no1 +Cc1cc(C(=O)NCCn2ncccc2=O)c(C)o1 +COc1ccc(NC(=O)C(C)n2cccn2)c(N)c1 +Cc1csc(C(C#N)C(=O)C2(c3ccc(F)cc3)CCCC2)n1 +Cc1cc(C)c(C)c(OC(=O)C2CC(=O)N(Cc3ccccn3)C2)c1 +CN(C)C(=O)N(C)C(C(N)=O)c1cccc(Br)c1 +N#Cc1cccc(CNC(=O)NCC(F)(F)F)c1 +O=S(=O)(NCc1ccc2c(c1)OCCO2)c1ccc(F)c(F)c1 +CC1(c2[nH]ncc2C(N)=O)CCCN(C(=O)c2ccccn2)C1 +Cc1cc(C)n(CC(=O)N2CCC(C)(O)C(C)C2)c(=O)n1 +CCOC(CC)C(=O)OCc1ccc2c(c1)OCO2 +Cc1cccc(C(=O)NC(C(N)=O)c2cccc(Br)c2)c1 +C#CC(OC(=O)COc1ccc2c(c1)CCC2)C1CC1 +NC(=O)CSc1nnc(SCC2CCCCO2)s1 +O=C(NCCC1CC1)NC1CCCN(Cc2ccccc2)C1=O +O=C(Nc1cccc(-c2nnco2)c1)c1cc(F)cc(F)c1 +CCN(CC(C)C#N)C(=O)c1ccc(-c2ccsc2)nc1C +O=C(Cc1c[nH]c2ncccc12)N(C1CC1)C1CCc2ccccc21 +O=C(Nc1cccc(-c2ccc(CO)cc2)c1)C1CC1 +OC(CN1CCN(c2cnccn2)CC1)c1cccc(F)c1 +CCCNC(=O)c1ccc(NCc2nc(C)cs2)cc1Cl +CCN(CC)C(=O)c1c(C)nc(N)nc1COc1cccc(C)c1 +Cc1nn(CC(=O)N2CCC(C)CC2)c2ccccc12 +COc1ccc(N2CC(NC(=O)N3CC(C)CC(C)C3)CC2=O)cc1 +Cc1nnc(NC(=O)c2ccc(OCc3nnnn3C)cc2)s1 +CC(=O)c1ccc(S(=O)(=O)NC(C)CN2CCOCC2)cc1 +O=C(CSc1ncc2ccccn12)NCCOc1cccc(F)c1 +Cc1ccc2cccc(S(=O)(=O)N3CCc4ccccc43)c2n1 +Cc1cc(CN(C)S(=O)(=O)Cc2cccc(F)c2)no1 +CC(C)NS(=O)(=O)Cc1ccccc1CNc1ncccc1F +CSc1ccc(CNC(=O)NCC2CCCC2O)cc1 +CCS(=O)(=O)N1CCC(NC(=O)NCCCOC)CC1 +CCOC(=O)C(C)NS(=O)(=O)c1cccc(Cl)c1C +CCn1c(C(=O)Nc2nc(C)cs2)cc2sccc21 +CCC(C)(O)CNC(=O)Nc1ccc(C(=O)NC(C)(C)C)cc1 +CC(C)c1csc(NC(=O)c2nc3ccccc3s2)n1 +COc1cccc(C(=O)N2CCOC(C3CCCO3)C2)c1F +CCc1ccc(S(=O)(=O)N2CCCC2CO)s1 +O=C(NCCCn1ccc2cccnc21)c1ccc(F)c(F)c1 +COCc1noc(CN2CCCCC2CCN2CCOCC2)n1 +O=C(CN1CCCOC1=O)OCCNC(=O)c1cccnc1 +COC1CCCN(C(=O)C(C)Oc2ccc3c(c2)OCO3)C1 +COc1ccccc1-c1ccc(=O)n(CC(N)=O)n1 +CCCc1cnc(C)nc1N1CCCN(C(=O)COC)CC1 +CC(CO)CNC(=O)NCc1cnn(-c2ccccc2)c1 +CC(OC(C)(C)C)C(=O)Nc1c(N)cc(Cl)cc1Cl +CN(C)C(=O)COc1cccc(CNc2ncnc3c2cnn3C)c1 +CCC(C)(C#N)NC(=O)c1ccn(-c2ccccc2)n1 +CCCOc1cccc(NC(=O)c2cc(S(N)(=O)=O)oc2C)c1 +Cc1ccc(-c2cc(C(=O)NCCCC(N)=O)n[nH]2)s1 +COc1cc(CNC(=O)C2CCOc3ccccc32)ccn1 +CCC(C(=O)N(CCO)Cc1ccccc1)n1cccn1 +CC(C)C(=O)N1CCCC1c1cc(CCO)[nH]n1 +CS(=O)(=O)N1CCOC(Cn2ccnc2-c2ccc(CO)o2)C1 +O=C(NCCN1CCOCC1)c1ccc(C(=O)c2ccccc2)cc1 +Fc1cccc(OC(F)F)c1CNCc1ccncc1 +CCC(C)NC(=O)CS(=O)(=O)c1ccccc1OC +CC1CN(CC(O)c2ccc3c(c2)OCCO3)CC(C)O1 +Cc1ocnc1CNC(=O)Nc1ccc(OC(F)F)c(F)c1 +COc1ccc(C2(CNC(=O)Nc3ccccn3)CCOCC2)cc1 +O=C(COC1CCCCC1)NC(CN1CCCC1=O)c1ccccc1 +Cc1sc2ncnc(N3CC(C(N)=O)CCC3C)c2c1C +CC(=O)Nc1ccc(C(=O)Nc2cc(F)ccc2C)cc1 +Cc1cc(Br)ccc1N(C)C(=O)COCC(F)(F)F +Cc1ccc(O)c(C(=O)Nc2ccc(CN3CCCC3=O)cc2)c1 +CCCOC1CCCN(C(=O)c2ccccc2O)C1 +COc1ccc(OC)c(NC(=O)CCC(=O)c2cccs2)c1 +Cc1cc(C)n(CC2(c3nc4c([nH]3)CC(C)(C)CNC4=O)CC2)n1 +O=C(NC1CC(=O)N(Cc2ccccc2)C1)c1ccc2[nH]cnc2c1 +CCOC(=O)c1ccc(-n2nnc(CO)c2C2CCC2)cc1 +OC1CN(c2cc(-c3ccccc3)nc3ncnn23)C1 +CN(Cc1ccc(C#N)cc1)C(=O)CCC(=O)c1ccc(F)cc1F +C=CCN(Cc1ccc(OC)cc1)S(=O)(=O)c1ccccc1F +C#CCN1CCN(CC(=O)NC2(C(=O)OC)CCCCC2)CC1 +NC(=O)c1ccc(NCc2ccccc2OC(F)F)cc1Cl +Cc1c2cn[nH]c(=O)c2c(C)n1Cc1ccccc1 +CC(=O)c1cccc(OCC(=O)Nc2sc(C)c(C)c2C#N)c1 +CCN(CC)S(=O)(=O)c1ccc2c(c1)CCN2S(=O)(=O)CC +Cn1nnnc1SCCC(=O)Nc1cc(Cl)ccc1O +CCOC(=O)CNC(=O)Cn1c(-c2nnc(C)o2)cc2ccccc21 +COCCNC(=O)CN1CCOc2ccc(C(C)=O)cc21 +Cc1ccc(NC(=O)Cn2nc(-c3ccco3)ccc2=O)cc1 +Cc1csc(C2CCCCN2C(=O)CCOc2ccccc2F)n1 +C=CCNC(=O)c1ccc(NC(=O)c2cccc3ccc(C)nc23)cc1 +CCc1ccc(C2COCCN2Cc2ccc(OC(C)C#N)cc2)o1 +Cc1c(C(=O)Nc2cccc(-n3cnnn3)c2)cnn1-c1ccncc1 +O=C(OCCc1ccccc1)c1cn(-c2ccccc2)nn1 +CCN1CC(=O)N=C1NCCc1cccc(Cl)c1 +C#CCN(C(=O)CN(CCc1ccccc1)C(C)=O)c1nccs1 +Cc1sc(NC(=O)c2cnccn2)c(C(N)=O)c1C +Cc1c(C(=O)OCCN2CCCC2=O)cnn1C +CCC1Oc2ccc(CO)cc2N(C(C)C(C)=O)C1=O +COC(=O)CN1C(=O)c2ccccc2OC1c1ccccc1 +Cc1nnc(SCC(=O)Nc2ccc(F)c(F)c2)s1 +CCOc1ccc(-c2nn3c(C)nnc3s2)cc1 +Cc1cc(C)c(C(=O)CCC(=O)NCc2ccco2)c(C)c1 +CCN(CC)C(=O)CSc1nc2ccccc2[nH]1 +O=C(c1ccccn1)N1CCc2onc(-c3ccncc3)c2C1 +CC(C)(C)C(=O)NCCC(=O)N1CCCC(CO)C1 +Cn1cccc1C(=O)Nc1ccccc1Sc1nccn1C +CCOC(=O)c1cccc(NC(=O)NCc2cnn(C)c2)c1 +COC(=O)C1CN(Cc2ccccc2C(C)(C)C#N)CCO1 +CC(CC#N)N(C)Cc1ccc(-c2ccccc2)cc1 +COc1cc(OC)c(OC)c2c1CCNC2c1cc[nH]n1 +Nc1ccccc1Sc1nnc2n1CCCCC2 +O=C(Nc1ccc(F)cc1F)c1ccc2nncn2c1 +CC(=O)c1nn(-c2cc(C)ccc2C)c(C)cc1=O +COc1ccc(-c2[nH]nc3c2CN(C(=O)c2ccccc2)CC3)cc1 +CCSc1cc(C(=O)Nc2cnn(CC3CCCO3)c2)ccn1 +N#Cc1cccc(NC(=O)C2CC(=O)Nc3ccccc32)c1 +O=C(C1CCN(c2ccc3nncn3n2)CC1)N1CCCCCC1 +O=C(NCCn1ccc2ccccc21)c1cccc(-n2cnnn2)c1 +CC(c1cccnc1)N1CCN(C(=O)C2CCOCC2)CC1 +COc1ccc(CCNC(=O)c2csc3c2CCCC3)cc1OC +Cc1cc(CN(C)C(=O)Nc2cccc(F)c2)on1 +CCc1nnc2n(CCCOC(C)C)c(=O)c3ccccc3n12 +Cn1cnc(CNC(=O)c2cc3ccc(Cl)cc3[nH]2)n1 +Cc1ccc(C)c(C(C)NC(=O)c2csc(C)n2)c1 +CCC(NC(=O)CNC(=O)C1CCCC1)c1ccc(OC)cc1 +C=CCn1c(C)nnc1SCc1coc(-c2cccs2)n1 +CC(C)(C)Oc1cc(CNC(=O)CSc2ccc(F)cc2)ccn1 +CC(C)(C)c1ccc(NC(=O)COC(=O)c2ccccn2)cc1 +CCC(CC)N(C)C(=O)c1cccc(NC(=O)c2cccs2)c1 +Cc1cccc(-c2c(N)nc(C)nc2C(F)(F)F)c1 +Cc1cnc(C(NC(=O)Cc2ccc(F)c(F)c2)C2CC2)s1 +COC(=O)c1cc(CN2CCc3cccc(Br)c3C2)c[nH]1 +Cc1cc(C)c2c(N3CCOCC3)cc(C#N)nc2c1 +COC(=O)c1cc(NC(=O)Cn2nnc3ccccc32)c(F)cc1F +COCCNC(=O)Nc1c(-c2cccnc2)[nH]c2ccccc12 +Cc1n[nH]cc1NC(=O)c1cc2cc(Cl)ccc2[nH]1 +CN(C)c1cccc(C(=O)Nc2ccc(C#N)cn2)c1 +Cc1ccccc1N(C(=O)c1ccc(-n2ccnn2)cc1)C(C)C +COc1ccc2c(c1)OCC(Cc1ncccc1C(N)=O)C2 +COC(=O)c1ccc(C(=O)Nc2cccc(CN(C)C(C)=O)c2)s1 +O=C(NCCc1cccnc1)C1(c2ccc(F)cc2F)CCCC1 +Cc1cnc(Cn2ccnc2-c2cccc(C(F)(F)F)c2)cn1 +CCOCC12CCCOC1CCN(C(=O)CC1=CCCCC1)C2 +CC1C(c2ccc(F)c(F)c2)CCc2nc(N)nn21 +O=C1CC(C(=O)N2CCOc3ccccc32)CN1CC(F)(F)F +COc1c(F)c(F)c(C(=O)NCc2cccnc2)c(F)c1F +Cc1ccc(C(=O)NCc2ccc(-n3ccnc3C)nc2)c(O)c1C +CC(=O)NCCCCCC(=O)Nc1ccc(C)c(Cl)c1 +COc1ccc(C(=O)NCc2ccc(F)cc2)cc1 +CCN1CC(COC(=O)c2ccc3nc(C)ccc3c2)CC1=O +CC(=O)c1ccc(NC(=O)NCc2cccc(N(C)C)c2)cc1C +COCC(=O)Nc1c(C(=O)Nc2cccc(F)c2)oc2ccccc12 +Cc1cc(C(=O)OCC(=O)NC2(C#N)CCCCC2)c(C)o1 +O=C(Cn1c(=O)oc2ccccc21)NCC(=O)Nc1ccc(F)cc1 +CCn1cc(S(=O)(=O)N(Cc2ccsc2)c2cccnc2)cn1 +COc1ccc(-c2cn3cccc(N)c3n2)c(C)c1C +CC(c1nc(C2CC2)no1)S(=O)(=O)c1ccc2ccccc2n1 +CSc1cccc(-c2ccccc2-c2nnc(C)o2)c1 +Cc1nc2ccc(-c3nc(C4CCOC4)no3)cc2o1 +CCCn1c(=O)c2ccccc2c2c(N)nn(CCO)c21 +NC(=O)C1CCN(C(=O)Nc2ccc(Cl)cc2)CC1 +CC1CCC(Oc2cc(CNC(=O)CCn3cncn3)ccn2)CC1 +Nc1cccc(CC(=O)Nc2ccc(F)c(F)c2F)c1 +O=C(CCc1ccc(Cl)cc1)N1CCOCC1C1CC1 +Clc1ccc(-c2nnc3sc(C4CC4)nn23)cc1 +Cc1nc2ncnn2c(NCc2ccc(F)cc2)c1C +CCOc1cc(NC(=O)CNC(=O)c2ccccc2)ccc1OC +Cc1nonc1CN(C)C(=O)CCC(=O)N1CCNC(=O)C1(C)C +COCCCNC(=O)COc1cc(C)c2c(C)nn(C)c2n1 +Cc1ccc(N)cc1NC(=O)c1ccc(OCC(C)C)cc1 +CC(=O)Nc1ccc(C(=O)Nc2cc(F)ccc2Cl)cc1 +COc1cccc(NC(=O)c2ccc3onc(-c4coc(C)n4)c3c2)c1 +CC(=O)c1cccc(NC(=O)NCCCc2nc(C(C)C)no2)c1 +CCOC(=O)c1cc(S(N)(=O)=O)cnc1C(F)(F)F +Cc1cccc(NC(=O)c2cn(Cc3ccccc3)nn2)n1 +CC1CCC(C(N)=O)CN1c1c(F)cc(N)cc1F +CC(C)(C)c1nc(CSc2nc3ccccc3n2CCC#N)no1 +COc1ccc(NC(=O)CNc2cccc(C(=O)N(C)C)c2)cc1 +CCn1nc(C)c(Cl)c1C(=O)Nc1cccc(C(C)=O)c1 +CNC(=O)Cn1nnc(CO)c1-c1ccccc1OC +Cc1ccc(S(=O)(=O)c2cc(O)ccc2O)cc1C +CCOC1CCCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)C1 +Cc1n[nH]cc1NC(=O)Cc1cccc(OCC#N)c1 +COc1ccc(NC(=O)C(NC(N)=O)C(C)C)cc1OC(F)F +Cc1n[nH]c(Nc2cccc(Cl)c2Cl)nc1=O +O=c1[nH]c2ccc(-c3nc(-c4cccc(Cl)c4)no3)cc2[nH]c1=O +COc1cc(C)ccc1OCn1nc(C)c(N)c1C +O=C(Cc1cccc(Cl)c1)N1CCN(C(=O)Cc2ccc[nH]2)CC1 +COc1ccc(C(C)(C)C)cc1C(=O)CC(C#N)C#N +COc1ccccc1C1CC(=O)c2cnc3cc(C)nn3c2C1 +C#CCCCOC(=O)c1ccc2c(c1)NC(=O)CS2 +COc1ccc(C)cc1NC(=O)Cn1ccc(=O)[nH]c1=O +CCNC(=O)C(C)NC(=O)NCc1ccccc1OC +CCOc1ccccc1CCC(=O)N1CCN(C(=O)N(C)C)CC1 +CCOC1C2CCC1N(Cc1ccsc1)CCO2 +CCOc1ccc(C(=O)NCC(=O)c2ccccc2)cc1 +NC(=O)CNC(=O)C1CCN(c2cc(Cl)ccc2Cl)C1=O +Cc1cc(CCNC(=O)c2cccn(C)c2=O)on1 +N#Cc1cc(F)c(N2CCN(CC(=O)N3CCCCC3)CC2)c(F)c1 +Cc1cc(SC(C(=O)NC2CC2)c2ccccc2)nc(C)n1 +CCCN1CCN(C(=O)Cn2c(C)cc3ccccc3c2=O)CC1 +C=CCn1c(SCC(N)=O)nnc1C1COc2ccccc2O1 +Nc1ccc(Cl)cc1NC(=O)c1ccc2ccccc2n1 +OCCCC(O)c1ccc(Oc2ccccc2)cc1 +CC(C)COc1ccc(NC(=O)c2cnc(C3CCCO3)s2)cn1 +O=C(NC1CCCC(C(F)(F)F)C1)Nn1cnc2ccccc21 +Cc1ccc(NC(=O)Cn2cnc3ccc(Cl)cc3c2=O)cc1 +Cc1ccc(N2CCC(C(=O)Nc3cccc(C(N)=O)c3)C2=O)cc1 +COc1cccc(Oc2ccc(CNC(=O)CC#N)cc2)c1 +O=C(CCNC(=O)c1ccco1)NCC12CC3CC(CC(C3)C1)C2 +Cc1cc(C(=O)NC(Cn2cccn2)c2ccccc2)c(=O)[nH]c1C +O=C(NCc1ccccc1Cl)c1cccc(F)c1F +Cc1cccc(Cn2cccc(C(=O)N(C)C(C)C(C)(C)C)c2=O)c1 +Cc1cc(Br)ccc1N(C)CC(=O)N(C)CCC#N +Cc1ccc(OCC(=O)Nc2nnc(-c3cc(C)nn3C)o2)cc1 +CCN(CC)c1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccc(C)cc1 +CC(O)CNC(=O)C(N)c1cccc(F)c1Cl +CCOC1CCN(C(=O)Nc2cccc(F)c2F)CC1 +NS(=O)(=O)N1CCN(c2ccccc2O)CC1 +COC(=O)Cc1cc(=O)[nH]c(SCc2ccc(OC)c(F)c2)n1 +Cc1ccncc1NC(=O)NC(C)CCc1ccc(O)cc1 +CCCc1c(C(=O)N2CCCC2)cnn1-c1ccc(F)cc1 +CCSc1nnc(N)n1CC(=O)NCc1ccccc1 +CC1CCCN(S(=O)(=O)N(C)C2CCC(C)(C)CC2)C1 +Cc1cc(C(=O)N(C)C(C)c2ccccc2Cl)no1 +Cc1nnc2n1CCN(C(=O)C1COc3ccccc3O1)C2 +COC(=O)CC(NC(=O)c1scnc1C1CC1)c1cccs1 +Cc1ccc(C(=O)OC2CCS(=O)(=O)c3sccc32)cc1 +COc1cc(NC(=O)c2ccncc2)cc(OC)c1 +Cc1cccc(C(N)C(=O)NCCC(C)(C)C)c1F +O=C(COc1ccccc1)NCc1ccc(Cn2ccnc2)cc1 +CC1(CNC(=O)c2cc(-c3cccs3)n[nH]2)CCOCC1 +CC(C)(CCC#N)CNc1cnn(-c2cccc(C(F)(F)F)c2)c1 +COc1cc(C)c(CCn2cc(N)cn2)cc1C(C)C +O=C(NC1CC1)N1CCCN(C(=O)c2ccsc2)CC1 +COc1ccc(C(=O)N2CCCC(C)(C(=O)NC3CCCC3)C2)cn1 +C=CCNC(=O)c1ccc(NC(=O)c2nc3nccc(C)n3n2)cc1 +Cc1cccc(OCCC(=O)N2CCC(c3nc(C)no3)CC2)c1 +CC(C)COc1ccc(C(=O)NCc2nnc3n2CCCCC3)cn1 +O=C1OCCC1Sc1nc(-c2cccs2)nc2ccccc12 +N#Cc1c(N)nc2c(c1-c1c[nH]nc1C1CCCCC1)CNCC2 +COc1ccc(-c2ccc(C(=O)NCC(C)O)o2)cc1Cl +COC(=O)CCCN(C)S(=O)(=O)c1c(C)sc2ccccc12 +CCOC(=O)C1CCCN(Cc2nc3ccccc3[nH]2)C1 +Cc1nc2ccccn2c1C(=O)NCCC(O)c1ccccc1 +Cc1cc(NC(=O)NCc2cccc(F)c2)n(Cc2ccccc2)n1 +C=CCCCN(C)C(=O)c1ccccc1S(C)(=O)=O +NC(=O)c1ccc(NC(=O)NC(c2nccs2)C2CC2)nn1 +Cc1cc(C(=O)Nc2nc3ccc4nc(C)sc4c3s2)c(C)o1 +CCCCCn1nc(C(=O)NCC2CCOC2)c2ccccc2c1=O +Cc1cc(C)cc(C(=O)Nc2nc(-c3c[nH]c(C(N)=O)c3)cs2)c1 +CC1CN(Cc2nc(N)c3c4c(sc3n2)CCCCC4)CC(C)O1 +CCc1onc(C)c1NC(=O)NC1CCN(c2ncccc2Cl)C1 +COc1ccc(CNC(=O)c2sc(CC(C)C)nc2C)cc1O +N#Cc1ccc(C(=O)Nc2ccc3c4c(c(=O)[nH]c3c2)CCC4)cc1 +O=C(Cc1nc(-c2ccccc2)n[nH]1)Nc1ccc(F)c(F)c1 +Cc1cc(COC(=O)c2ccc(F)cc2F)nc(C)n1 +CSc1ncccc1C(=O)Nc1cccc(C(C)=O)c1 +Cn1cc(C(=O)N2CCC3OCCCC3C2)c(C(C)(C)C)n1 +O=C(NCCCc1ccccc1)NCC1(O)CCOCC1 +O=C(Nc1cccc(F)c1)c1cc(=O)c2ccccc2o1 +Cc1ccc(NC(=O)N(Cc2ccccn2)Cc2ccco2)cc1 +Cc1cccc(NC(=O)c2cc(C)n(C3CC3)c2C)c1 +Cc1ccc(C(=O)OCC(=O)Nc2ccccc2)cc1F +C#CCNC(=O)COc1ccc(C(=O)OCC)cc1 +COc1ccc(OC)c(NC(=O)C2CN(C(=O)c3cnccn3)C2)c1 +CC(C)N1C(=O)C(=O)c2cc(Cl)cc(Cl)c21 +O=C(Cc1ccc(Cl)cc1Cl)NCCCN1CCCC1=O +O=C(NCC1(c2ccc3c(c2)OCO3)CCCCC1)c1csnn1 +CN(Cc1ccccc1)CC(O)c1cccc(F)c1 +CCOC(=O)C(NC(=O)c1ccc(Cl)cc1)C(C)C +COC(=O)c1ccccc1NC(=O)C(C)Oc1ccccc1OC +CC(=O)N1CCN(C(=O)C(C)(C)Oc2ccc(Cl)cc2)CC1 +Cc1ccnc(Nc2nc(CC(=O)Nc3ccc(C#N)cc3)cs2)c1 +CCOC(=O)CNC(=O)c1nccc2c(N)c(Cl)ccc12 +COc1cc(C(=O)NCC(N)=O)cc(Cl)c1OCC(C)C +CCN(Cc1noc(C)n1)C(=O)c1ccc2cccc(Cl)c2n1 +CC(=O)c1ccc(NC(=O)c2csc(-c3ccsc3)n2)cc1 +CC1Cc2cccc3c(=O)c(C(=O)NCC4CCCO4)cn1c23 +COc1cc(C#N)ccc1OC(C)C(=O)NC1CC1 +CC(C)(CCCNC(=O)c1ccc2c(c1)OCCCO2)C1OCCO1 +O=C(NCC(O)c1cccs1)c1ccc2ccccc2c1 +CCC(C)n1ncc(C(=O)NCC(F)F)c1C1CC1 +CCCC(C)NC(=O)C(C)N1CCN(c2ccccc2OC)CC1 +Cc1cc(NC(=O)CN(C)C(=O)Cc2ccccc2F)no1 +Cc1cc(OCc2nc(C(=O)NC(C)C)cs2)ccc1Cl +COC(C)(C)C(=O)N1CCC(c2ccc3c(c2)OCO3)C(O)C1 +O=C(NC(n1cncn1)C(Cl)(Cl)Cl)c1ccccc1 +CC1(C)Oc2ccc(NC(=O)Cn3c(=O)[nH]c4ccccc43)cc2O1 +c1ccc(CCc2noc(CN3CCOCC3)n2)cc1 +Cc1ccccc1NC(=O)Nc1ccc(C#N)cc1 +Nc1cc(=O)[nH]n1C1CCN(c2ccccc2)CC1 +COc1ccccc1N1CC(C(=O)NCCNC(=O)C2CC2)CC1=O +COc1cc(C(=O)Oc2ccccn2)cc(OC)c1OC +O=C(CN1CCN(c2ccc3c(c2)OCCO3)C1=O)NC1CC1 +COC(=O)c1cnn2c1ncc1c(=O)n(-c3cc(C)ccc3C)ccc12 +O=C(c1cccc(C(F)(F)F)c1)N1CCN(C(=O)C2CCC2)CC1 +CCOc1ncnc2c1[nH]c1cc(OC)c(OC)cc12 +COc1cc2c(cc1C(=O)Nc1cccc(C(C)=O)c1)OCCCO2 +N#Cc1ccc(CN(CCO)c2ccccc2)cc1 +Cc1cc(C)c(CNC(=O)c2cnc3ccccc3n2)c(=O)[nH]1 +CC(Cc1cccc(Cl)c1)NC(=O)NCC1CCOC1 +CNC(=O)Cc1c2c(n(Cc3ccccc3F)c1C)CCCC2=O +COc1ccc2nc(-c3nn4c(C(C)C)nnc4s3)ccc2c1 +CCC1c2cccn2CCN1C(=O)c1cnn(Cc2ccccc2)c1 +Cc1cc(COC(=O)c2cccc(-n3cnnn3)c2)no1 +CC(C)CS(=O)(=O)Nc1ccc2c(c1)CC(=O)N2C +NC(=O)c1csc(NC(=O)C2CC2c2ccccc2Cl)n1 +O=C(Nc1ccccc1O)c1nn(-c2ccccc2)c2c1CCC2 +Cc1cccc(C)c1OCC(=O)NCC1COc2ccccc2O1 +CC(C)N(C)C(=O)c1cc(Br)ccc1Cl +N#Cc1ccc(NC(=O)NCCCN2CCc3ccccc32)cc1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)Nc1cccc(C(F)(F)F)c1 +O=C(NCCCO)C1CCCN(C2=NC(Cl)=NC3=NC=NC32)C1 +COC(=O)C1CC(=O)N(c2ccc3c(c2)Cc2ccccc2-3)C1 +CC(C)n1cnnc1SCc1ccn(-c2ccc(F)cc2)n1 +COc1cc(C(=O)N(C)CC2CC2)cc2occc12 +COc1ccc(NC(=O)CSc2ncnc(N)n2)cc1 +CC1CCN(C(=O)C2CCC(=O)N(C)C2c2cccs2)CC1 +Cc1cc(CN(C)C(=O)Nc2ccc(C)c(-n3cnnn3)c2)no1 +Cc1cc(=O)c(CO)nn1-c1ccc(Cl)cc1 +CC(=O)Nc1ccc(NCc2coc(-c3ccc(C)cc3)n2)cc1 +Cc1ccccc1OCC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +CC(C)(CNC(=O)c1ccc(-c2cscn2)cc1)N1CCOCC1 +Cc1ccc(N2CCCN(C(=O)C(C)OCC3CC3)CC2)nn1 +COc1ccc(OC)c(CCC(=O)N2CCC(C(N)=O)C2)c1 +CC1CC1CNC(=O)c1cnn(-c2ccccc2)n1 +O=C(Nc1cc(F)cc(F)c1)NC1CCN(c2ccc(F)cc2)C1=O +COC(=O)c1c(SC)nn(-c2nc3ccccc3s2)c1N +Cc1ccc(S(C)(=O)=O)c(-c2cc(C(=O)OC(C)C)n(C)n2)c1 +CCCOC(=O)Cn1c(C(C)C)nc2c(N)cccc21 +CCCn1cnc2c(SCc3ccccc3)nc(N)nc21 +CC(C)CN(C)C(=O)NCc1cn2ccsc2n1 +Cc1cc(C(=O)N(CCO)Cc2nccs2)c2ccc(F)cc2n1 +CC(Sc1nnc(CCc2ccccc2)o1)C(F)(F)F +O=C(CNC(=O)c1ccccc1Cl)NCC1CCOC1 +CC1CN(C)CC(C)N1C(=O)c1ccc(Cl)cn1 +CCCCN(C)Cc1c(O)c(=O)cc(C)n1Cc1ccncc1 +Cc1ccc2c(c1C)OCC(O)C2N1CCOCC1 +Cc1ccccc1OCC(=O)NCC1CN2CCCCC2CO1 +O=C(Nc1cc2c3c(c1)CCC(=O)N3CCC2)c1ccc(F)cc1 +N#Cc1cnc(SCc2cn3ccccc3c2C#N)nc1N +O=C(Nc1ccccc1F)c1ccc(O)c(Cl)c1 +C=CCn1nc(C(=O)OCC)c2c1CCN(Cc1cn(C)nc1C)C2 +CS(=O)(=O)Nc1ccc(C(=O)N2CCCCC2)cc1 +COc1ccc2c(c1)C(c1ccc(CO)cc1)NCC2 +COCCNC(=O)c1cccnc1Nc1cccc(C(F)(F)F)c1 +COc1ccc(-c2cnnc(N)c2C(=O)NC2CC2)cc1F +CN(C)c1ccccc1NC(=O)NCc1nnc2n1CCCCC2 +CCCc1ncc(C(=O)N(C)C2CCCCC2)c(N)n1 +Cc1cc(C)c(NC(=O)CNC(=O)CC(C)(C)C)c(C)c1 +COc1ccc(Cc2nn(-c3nccs3)c3c2CNCC3)cc1 +Cc1cc(Oc2ccc(F)c(F)c2)nc(C)c1N +CCCc1ccc(OCC(=O)C(C#N)c2nc3ccccc3[nH]2)cc1 +COC(=O)N1CCC(NC(=O)NCCc2ccccn2)CC1 +Cc1ccc(S(=O)(=O)c2ccc(Cl)cc2)cc1S(N)(=O)=O +CC(=O)c1c(C)[nH]c(C(=O)Nc2nc3ccccc3[nH]2)c1C +Cn1cc(C(=O)Nc2ccc(Cl)c(C(=O)NC3CC3)c2)ccc1=O +O=C(CCCn1ccc2cc(Cl)ccc21)NC1CC=CC1 +Cc1nc(COc2ccc(C(=O)NC(C)C3CC3)cc2)no1 +O=C(NCC(=O)N1CCCC1c1cccnc1)OCC(F)(F)F +FC(F)CN(Cc1cccc2c1OCCCO2)C1CC1 +COC(=O)CCCS(=O)(=O)N1CCc2ccccc2C1 +Cc1ccc(CNS(=O)(=O)c2cccs2)c(C)c1 +COc1ccc(Cl)c2c1N(C(=O)c1ccnc(F)c1)CCC2 +Cn1cc(CNC(=O)NCCNc2ncc(Cl)cc2Cl)cn1 +Cc1ccc(C(=O)NCC(=O)c2ccc(F)cc2)cc1C +Cc1ccc(CNC(=O)CCCC(=O)N(C)C)c(C)c1 +CCC(NC(=O)C1CCOC1)c1cccc(Cl)c1 +O=C(COc1ccc(Cl)c2cccnc12)N1CCOCC1C1CC1 +CCOC(=O)C1CCCN(C(=O)Cc2cccnc2)C1 +Nc1cc(Cl)ccc1OCC(=O)NCC(F)(F)F +CC1CCCN(c2nc3c(cc2C#N)CCCC3)C1 +Cc1cc(C)c2c(n1)oc1c(NCc3ccccc3)ncnc12 +COCC(C)NC(=O)Nc1ccnn1CC(C)C +Cc1nc(NC(=O)NCc2cccc3c2OCO3)oc1C +CN(CC1CC1)S(=O)(=O)c1ccc(C(=O)N2CCOCC2)cc1 +Cc1ccc(S(C)(=O)=O)cc1NCc1coc(-c2cccs2)n1 +Cc1nc(C2CCCCCN2C(=O)Nc2cnccc2C)no1 +Cc1cc(C2CCCN2C(=O)Nc2nnc(C(C)C)s2)no1 +Cc1ccc2cc(CNC(=O)c3ccc(F)cc3)c(=O)[nH]c2c1C +O=C(NCc1cccc(CN2CCCC2=O)c1)c1cc[nH]n1 +Cc1nc(C)c(OCc2nc(CCc3ccccc3)no2)c(C)n1 +N#Cc1cnc2c(Cl)cc(F)cc2c1N1CCN(CCO)CC1 +COc1ccc(C)cc1NC(=O)c1cnc2ccc(C)cn2c1=O +O=C(c1cc(Cn2ccc3ccccc32)[nH]n1)N1CCOCC1 +CC(C)(C)c1ccc(S(=O)(=O)CCc2ccccn2)cc1 +CCCOCC(=O)NC(C)c1cccc(S(N)(=O)=O)c1 +O=C(Cc1ccccn1)c1cc2c(s1)CCCC2 +CCOCC1CN(S(=O)(=O)N(C)C)Cc2cnn(CC)c21 +CC(C)Nc1ncnc2c1CCN(C(=O)Cc1ccccn1)CC2 +CC(n1ncc2cc(C(N)=O)c(N)nc21)C(C)(C)C +COc1ccc(-c2cc(OC)nc(N)n2)c(OC)c1 +O=C1N(CC2CC2)CCC12CCN(c1ncccn1)CC2 +CCOc1ncccc1NC(=O)c1ccc(=O)[nH]c1 +CN(CC(O)C1CC1)C(=O)CC1OCCc2ccccc21 +NS(=O)(=O)CCCNC(=O)C1(c2cccc(Cl)c2)CC1 +N#Cc1ccnc(N2CCN(C(=O)Nc3cccnc3)CC2)c1 +CN(CC(=O)NC(C)(C)c1cccc(F)c1)c1ncnc2[nH]cnc12 +COC(=O)CCC(=O)Nc1nc(-c2cccs2)cs1 +Cc1noc(C)c1C(C)NC(=O)c1cccc(S(C)(=O)=O)c1 +COC(=O)C(CC(=O)c1cccc(OC)c1)c1ccc(F)cc1 +CCOc1ccc(C(=O)NCC(=O)NC(C)C)cc1 +CCOC(=O)c1[nH]c2c(c1N)C(=O)CC(C)(C)C2 +CCCN(CCC)S(=O)(=O)N1CCCC(O)C1 +COc1ccccc1C(C)NC(=O)CCc1nc(C)no1 +O=C(OCc1ccccc1)C1CCN(C(=O)c2cccs2)CC1 +CCN(C(=O)c1ccc(OC)c(N)c1)c1ccccc1 +CCOCCC(=O)N(C)Cc1csc(C#CCN)c1 +CN(C)c1nc(N)nc(CNc2nccc(C3CCCC3)n2)n1 +CN(CCc1ccccc1)C(=O)c1cccc(OCC2CCCO2)c1 +Cc1ccc(C)c(C(=O)Nc2sc(C)c(C)c2C(N)=O)c1 +Cc1nc(C)c(CNC(C)c2ccc(C(F)(F)F)cc2)s1 +Cc1cccc(C(=O)Nc2cnn(C)c(=O)c2N2CCCCC2)c1 +Cc1ccnc(SCc2cn3c(C)cc(C)nc3n2)n1 +Cc1ccc(-c2c(CO)nnn2Cc2cccc(F)c2)cc1 +O=C(Cn1cnc2ccc(Cl)cc2c1=O)NCC1CCCO1 +O=C(NCCCc1nnc2ccccn12)c1c[nH]nc1-c1ccccc1 +Cc1ccc(Cl)c(OCC(=O)c2c[nH]c(C(=O)N3CCCC3)c2)c1 +O=C(NCc1ccco1)c1nc(-c2cnccn2)no1 +CC(C)(C)NC(=O)CC(C#N)c1ccccc1Br +Cn1nnnc1N1CCC(NS(=O)(=O)c2cccc(F)c2)CC1 +CC(C)NC(=O)c1ccc(COCC(F)(F)F)cc1 +CC(Cc1ccccc1F)NC(=O)Nc1ccc2c(c1)OCC(=O)N2 +C#Cc1cccc(NC(=O)NCc2ncn(C)n2)c1 +CN(C(=O)c1ccc(-n2cnnn2)cc1)C1CCCCC1 +Cc1cc2nc(CCNC(=O)C3CCCN(C(N)=O)C3)[nH]c2cc1C +CCC(=O)c1ccc(OCC(=O)N2CCN(C(C)=O)CC2)cc1 +CCn1c(=NC(=O)c2ccoc2C)[nH]c2ccc(Br)cc21 +Cc1cccc2sc(NC(=O)C3CC(=O)N(C(C)(C)C)C3)nc12 +Cc1oc(-c2ccccc2)nc1COc1ccccn1 +CC1(C)COCCN1C(=O)c1csc(-c2ccc3c(c2)OCO3)n1 +CC(C)NC(=O)C(NC(=O)c1cc2ccoc2s1)c1ccccc1 +CN1C(=O)CN(C(=O)c2cccc(OCC(F)F)n2)c2ccccc21 +CN(C)S(=O)(=O)N(C)CCCOc1cccc(Cl)c1 +CCOC(=O)c1cc(NC(=O)NCCc2cccnc2)c[nH]1 +CNC(=O)Nc1ccc(Br)cc1C(C)C +CC(C)Cc1ccc(C(O)Cn2cnc3ncccc3c2=O)cc1 +NS(=O)(=O)c1c(F)cc(F)cc1Br +CCC1CCCN(C(=O)c2csc(-c3ncccn3)n2)C1 +CC(C)Cn1c(-c2cccs2)ccc(CC#N)c1=O +CC(C)OCCC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +O=C(Cc1nc2ccccc2n1C(=O)c1ccccc1)N1CCOCC1 +Cc1ccc(F)c(NC(=O)c2cccc(-n3cnnn3)c2)c1 +CC(NC(=O)CSc1nncn1C)c1ccc(F)cc1 +COCC(C)NC(=O)C1(c2cc(-c3ccc(Cl)cc3)on2)CC1 +CC(=O)Nc1ccc(CNC(=O)C2COc3ccccc3O2)cc1 +Cc1cc(NC(=O)C(C)N2CCN(c3ncccn3)CC2)on1 +CCN(CC)C(=O)c1cn(Cc2ccccc2)nc1-c1cccs1 +Cc1ncc(-c2nc(-c3c[nH]c4ccccc34)no2)c(=O)[nH]1 +Cn1cc(NC(=O)NCc2nc3ccccc3s2)cn1 +COc1ccccc1C(=O)CNC(=O)c1cccc(C)c1 +COC(=O)c1noc(C(=O)NCCN2CCOCC2)c1N +CC(NC(N)=O)C(=O)N(Cc1ccc(Cl)cc1)C1CC1 +COc1cc2nc(CNCCn3cc(C)cn3)[nH]c(=O)c2cc1OC +COc1cc(C(=O)N(C)C2CCCC(C)C2)cc(OC)c1OC +CCOC(=O)C1=C(C)C(S(=O)(=O)N=c2cccc[nH]2)C(C)=N1 +CC(O)CN1CN=C(NS(=O)(=O)C(C)C)NC1 +Cc1ncc(CN2CCOC(C(=O)NC3CCCC3)C2)s1 +CCCn1c(C)nnc1SC(C)C(=O)NCc1ccccc1F +CCOc1cccc(NC(=O)C(C)NS(C)(=O)=O)c1 +CC(C)CNC(=O)c1cccc(NC(=O)CSc2ccccc2)c1 +CC(C)C(=O)N1CCC(Nc2ncccc2C#N)CC1 +CCC(=O)N1CCN(C(=O)NC2CC2c2cccc(Cl)c2)CC1 +O=C(c1cccc(F)c1)N1CCN(C2CC2)CC1c1ccccc1 +COC(=O)c1c(-c2ccc(SC(C)C)cc2)noc1N +C=CCNC(=O)Nc1ccc(OC)c(OCC(F)(F)F)c1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1cc(C)oc1C +Fc1cccc(-c2n[nH]cc2-c2nc(CN3CCOCC3)no2)c1 +CN(CC(=O)NC1CCSc2ccccc21)S(C)(=O)=O +CCCNc1nc(-c2ccc(C(C)C)n(CC)c2=O)cs1 +COC(=O)C1CCN(C(=O)c2c(Cl)cccc2Cl)CC1 +O=C(CSc1nnnn1-c1ccccc1Cl)Nc1ccccc1 +COC(=O)c1[nH]c2cc(Br)ccc2c1N +Cc1cc(-c2c(-c3ccccc3)ncn2C2CC=CC2)[nH]n1 +CC(C)c1noc(CCC(=O)Oc2cccc(Br)c2)n1 +CC(=O)Oc1ccc(NCc2ccccc2F)cc1 +CN(C)C(=O)c1ccccc1NCc1nccn1Cc1ccccc1 +CCC(NC(=O)COc1cccc(C(N)=O)c1)c1cccc(Cl)c1 +CN(C)C(=O)COc1cccc(CNC(=O)C2CC=CC2)c1 +COc1cc(C)c(S(=O)(=O)NC(C)C2CCCO2)cc1OC +CCCCn1nc(C(=O)Nc2nc(C)cs2)c2ccccc2c1=O +Cc1c(Br)cccc1CN1CCNC(=O)CC1 +Cc1cc(NC(=O)C2CCN(C(=O)c3ccccc3Cl)CC2)no1 +CCn1cc(Br)cc1C(=O)NCCc1ccc(O)cc1 +O=C(CSc1nnnn1-c1ccccc1)NCCC1=CCCCC1 +CCOC(=O)c1cnc(-n2nc(C)cc2C)nc1N1CCC(C)CC1 +CCNC(=O)c1ccc(NC(=O)C(CC)OCC)c(C)c1 +CC1CCCN(C(=O)Nc2cccn(Cc3ccc(F)cc3)c2=O)C1 +CCCC(C)N1CC(c2nc(-c3cccs3)no2)CC1=O +CC(=O)N1CCC(c2cnc(-c3ccc(N)nc3)cn2)CC1 +CSc1ccc(CNc2c(C)cccc2N)cc1 +CC(CCO)CNC(=O)NC1CC1c1ccccc1Br +Cn1cc(NC(=O)CCOc2ccccc2Br)cn1 +O=C(NCCCN1CCOCC1)c1ccc2[nH]cnc2c1 +Cc1ccc(C(=O)N2CCN(C(C)c3ccccc3)CC2)cc1 +CN1C(=O)Cc2cc(C(=O)NC3CCCC3)ccc21 +Cc1ccc2nc(N(Cc3cccnc3)C(=O)c3ccco3)sc2c1 +CCc1ncc(C(=O)N2CCCc3ccccc32)c(N)n1 +NC(=O)CCCNC(=O)CCc1cc(F)ccc1F +Fc1ccc(CC2NCCc3ccc4c(c32)OCCO4)cc1 +Cc1ccccc1C(=O)Nc1ccc(N2CCCS2(=O)=O)cc1 +COCCN(CC(C)C)C(=O)c1ccc(OC)c(F)c1 +CCn1cnnc1CNC(=O)c1ccc(OC)c(Br)c1 +O=C(Cc1cccs1)NC1CCN(c2ccccc2Cl)C1=O +CCOC(=O)C(C)(C)N(C)Cc1cccnc1C +COc1ccc(CC(=O)NCC(C)(C)c2ccncc2)c(Cl)c1 +CC(C)(C)n1cc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cn1 +O=C(NCCNC(=O)c1ccco1)c1cc(F)cc(F)c1 +COc1ccccc1OCC(=O)Nc1ccc2c(C)cc(=O)[nH]c2c1 +Cc1n[nH]cc1CNC(=O)c1ccc(-n2cncn2)nc1 +Cc1cccc(OCCNC(=O)c2cccs2)c1 +CC1CCN(C(=O)CNc2ccc(F)cc2F)CC1 +CCOC(=O)c1[nH]c(C)c(C(=O)NCc2cccn2C)c1C +CC(C)NC(=O)C1(c2ccc(NS(C)(=O)=O)cc2)CC1 +Cc1ccc(C(=O)NCCNC(=O)c2nonc2N)cc1 +CN(C(=O)CSc1nnc(Cc2ccccc2)o1)C1CCCCC1 +CCc1cc(C#N)c(NC(=O)C2CC3C=CC2C3)s1 +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)NCC1CCOC1 +C#CCN1CCN(C(=O)NCc2cccc(OCCOC)c2)CC1 +CC1CN(C(=O)Cc2cccc(F)c2)CC(C)O1 +Cc1cc(C)n(CCC(=O)NC2CCc3nnc(C)n3C2)n1 +O=C(CCn1ccc2ccccc21)N1CCCN(c2cccnn2)CC1 +COC(=O)C(O)c1ccc2c(c1)NC(=O)C(C)S2 +CC(=O)c1c(C)[nH]c(C(=O)NC(C)c2ccncc2)c1C +COc1ccc(OC)c(COC(=O)c2sc(C)nc2C)c1 +CC(C)(C)C(=O)NCCCC(=O)Nc1ccc(N2CCCCC2)cn1 +O=c1c2ccncc2ncn1CC1CCc2ccccc2O1 +Cc1cc(C)n2nc(C(=O)Nc3cccn(C)c3=O)nc2n1 +O=C(NCCc1cn2ccsc2n1)c1cn(CC2CCCO2)nn1 +Cn1cnc(CNC(=O)c2ccccc2C(=O)c2cccs2)n1 +COc1ccc(OCC(=O)N(C(C)C)C2CCC2)cc1 +Cc1ccc(N2CC(C)N(C(=O)C3CCC3)CC2=O)cc1 +Cn1ccnc1SCC(=O)NCCC(C)(C)C +COCc1c(C(=O)NCC(F)(F)F)oc2ccccc12 +NC(=O)c1cc2n(n1)C(C(F)(F)F)CC(c1cccs1)N2 +CC(C)Sc1ccccc1NC(=O)Cc1cccnc1 +O=C(Cc1ccc(Cl)cc1Cl)Nc1ccccc1-n1cnnn1 +O=C(Nc1cccc2[nH]cnc12)c1cc2ccccc2c(=O)[nH]1 +Cc1cc(NC(=O)CNc2ccc3oc(=O)n(C)c3c2)n(C)n1 +Cc1nnsc1C(=O)NCC1(O)CCOCC1 +CCOc1ccc(C(=O)C(C#N)c2ccccn2)cc1OC +CCC(CC)NC(=O)CN1c2ccc(S(N)(=O)=O)cc2CC1C +CCCn1c(SCC(=O)Nc2ccc(Cl)cc2C)n[nH]c1=O +CCn1cnnc1CNC(=O)NCc1ccc(C)nc1 +Cc1cc(-c2cn(Cc3ccccc3)cc2N)sn1 +O=S1(=O)N=C(CSc2nc3ccccc3o2)Nc2ccccc21 +O=C(Cc1ccccc1)N1CCC2CNS(=O)(=O)C2CC1 +CSc1cccc(N2CC(C(=O)NC(C)(C)C)CC2=O)c1 +CCOc1ccc(C(=O)NCC(=O)Nc2c(C)cc(C)cc2C)cc1 +Cc1ccc(C)c(-n2nnnc2-c2cccc(N)c2)c1 +COc1cccc(-c2nnn(CC(=O)N(C)CC(F)(F)F)n2)c1 +CC(=O)Oc1ccc2oc(C)c(C(=O)OC(C)C)c2c1 +O=C(c1ccc(Cl)cc1)N1CCc2sccc2C1 +CNc1nc(CNC(=O)Nc2cc(C#N)ccc2C)cs1 +Cc1cc(C2CCCN(Cc3nc4c(F)cccc4[nH]3)C2)n[nH]1 +O=C(Nc1cc(F)c(Br)cc1F)c1ccco1 +Cc1c(C(=O)Nc2ccccc2)sc2[nH]c(=O)[nH]c(=O)c12 +COc1cc(C)c(S(=O)(=O)N2CCN(C)CC2)cc1C(C)C +O=C(NC1c2ccccc2CC1O)c1ccccc1-n1cnnn1 +Cc1c(Cl)cccc1N(CC(=O)N1CCCCC1)S(C)(=O)=O +O=C(NCc1ccc(NC(=O)C2CC2)cc1)c1cccc(Cl)c1 +Cc1nn(C)cc1CN(C)C(=O)Nc1ccccc1Cl +O=C(NCC(=O)N1CCc2ccccc21)c1cccs1 +CCNc1nc(NCC)nc(-n2nc(C)cc2C)n1 +CCN(CC)c1ncnc(NCC2CCCO2)c1N +CCC(=O)Nc1nnc(-c2ccccc2F)s1 +COc1ccc(CN(C)C(=O)c2cc(C3CC3)n(C(C)(C)C)n2)cc1 +CN(c1ccccc1)c1nc2c(s1)C(=O)CCC2 +Cc1nc(-c2cc(C(=O)N(C)Cc3ccncc3)n(C)c2)cs1 +O=C(NCc1ccc(CO)c(F)c1)Nc1ccccc1C(F)(F)F +CNC(=O)c1cccc(COc2cccc(F)c2)c1 +CCOc1ccccc1C(O)CCc1nc(C)cs1 +CCCN(CCC)C(=O)c1[nH]c(C)c(C(C)=O)c1C +CC(C)N(C)S(=O)(=O)N1CCc2ccc(N)cc21 +COc1ccc(OCCCNC(=O)N2CCC(C(N)=O)CC2)cc1 +O=C(NC1CC1)c1ccccc1NCCOc1ccccc1 +CS(=O)(=O)c1ccc(NCCCC2CCCCC2O)cc1 +O=C(c1ccccc1)N1CCN(c2ccc(F)cc2)CC1 +O=C(c1cscn1)N(CC(F)(F)F)C1CCCOC1 +Cc1ccc2nc(CNC(=O)c3cccc(Cl)c3)[nH]c2c1 +Cc1nsc(NC(=O)NC(c2ccccn2)C(F)(F)F)n1 +COc1cccc(C(=O)NCc2ccc(OCc3cccnc3)cc2)c1 +Cc1ccc(CNC(=O)c2cn(C)nc2C(C)(C)C)s1 +CCOc1ncccc1NC(=O)NC(C)C(=O)NC(C)CC +Cc1cn(C)nc1C(=O)Nc1nnc(-c2cccs2)o1 +Cn1cccc(NC(=O)CCCC2CCCCC2)c1=O +O=C(Cn1ccn(CCc2ccccc2)c(=O)c1=O)Nc1ccccc1 +Cc1c(C(C)NC(=O)c2c[nH]c(=O)[nH]c2=O)cnn1-c1ccccc1 +CN(Cc1ccccc1N1CCCC1)C(=O)Cc1c[nH]c2ccccc12 +CC(C)CN(Cc1ccsc1)C(=O)c1cccc(-n2cnnc2)c1 +Cc1cccc(C)c1NC(=O)Cc1ccc(F)c(F)c1 +Cc1noc(C)c1C(C)NC(=O)Nc1cc(F)cc(N2CCCC2)c1 +Cc1nc(C2CCCN2C(=O)c2ccc(OCC3CC3)nc2)no1 +COCCOc1cc(C)ccc1NC(=O)N1CCOCC1C1CC1 +O=C1COC2CN(Cc3ccccn3)CC2N1Cc1ccccc1 +CC(C)OCCCNC(=O)C1CC(=O)Nc2cc(F)ccc21 +COc1ccc(C(=O)C2CC2)cc1S(=O)(=O)N1CCCC1 +N#Cc1cnnc(-c2ccc(Br)cc2)c1 +Clc1cccc(N2CCN(Cc3nnnn3C3CCCC3)CC2)c1 +OCCn1nc(CO)cc1-c1ccc(-c2ccccc2)cc1 +CCOc1ccc(NC(=O)CNC(C)=O)cc1CO +Cc1c(CN2CC(c3ccccc3Cl)OCC2C)cc(C#N)n1C +Cc1cc(CNC(=O)Nc2ccccc2S(=O)(=O)C(F)F)on1 +COc1ccsc1C(=O)OCCc1cccnc1 +Cc1ccc2[nH]c3c(=O)n(CCC(=O)NC4CC4)cnc3c2c1 +CCCC(=O)Nc1cccc(NC(=O)c2cnccn2)c1C +CC(=O)Nc1cccc(NC(=O)CCC(=O)c2ccc(F)cc2)c1 +CCOc1ccc(Nc2ncnc(-n3nnc4ccccc43)c2N)cc1 +O=C(Cn1nnc(-c2cccs2)n1)N1CCCc2ccccc21 +O=C1CCN(c2cc(-c3ccncc3)ncn2)CC1 +CCNC(=O)c1ccc(NC(=O)NCc2nncn2CC)cc1 +COc1ccc(NS(=O)(=O)c2ccc(F)c(F)c2F)cc1OC +Cc1ccc(C(=O)NCC(=O)N2CCCC2c2ccccc2C)cc1 +Cc1c(N)ccc2c1N(C)S(=O)(=O)C21CCCC1 +CCCOc1cc(NCC2COc3ccccc3O2)ncn1 +COc1ccccc1CN(C)C(=O)COc1ccc(CO)cc1 +Cc1nnc(NC(=O)CCn2c(=O)oc3ccc(Cl)cc32)s1 +CCOc1ccccc1C(CC)NC(=O)NC(C)C +Cn1ncc(-c2nc3c([nH]2)c(C2CC2)nn3C)c1-c1ccccc1 +CCOC(=O)C1CCN(C(=O)Cn2c(=O)oc3ccccc32)CC1 +O=C(NC(CO)Cc1ccccc1)c1cc(F)c(F)cc1F +Cc1nc(N2CCCCC2)ncc1C(=O)NCc1ccccc1Cl +COc1ccc(OC)c(-c2cc(CO)nn2CC(C)C)c1 +CNS(=O)(=O)c1ccc(CNC(=O)c2cc(C)on2)s1 +CSc1cccc(NC(=O)Cc2ccccc2)c1 +Cc1noc(C)c1S(=O)(=O)Oc1cccc(Cl)c1 +CC(C)(C)NC(=O)c1ccccc1NC(=O)c1ccc(F)cc1 +COc1cccc(OCC(=O)Nc2ccc(N3CCCC3=O)cc2)c1 +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)Nc1nccs1 +CN(C)C(=O)CNc1nc2sc3c(c2c(=O)n1C)CCCC3 +CCC(C)OC(=O)c1c(N)n(CCOC)c2nc3ccccc3nc12 +CCN1CCN(C(=O)c2ccnc(-n3cncn3)c2)CC1 +CC(C)n1nccc1NC(=O)N(C)CCCOc1ccccc1 +Cn1cccc1C(=O)N1CCOC2C(OCC3CC3)CCC21 +COC(=O)c1ccccc1CN(C)c1cnn(C)c1 +Cc1ccc(OCc2cccc(C(=O)NCCC3CCCO3)c2)cn1 +Cc1cc(C)c(NC(=O)Cn2ncc(=O)c3ccccc32)c(C)n1 +CCCNC(=O)C1CCCN(C(=O)NC2CCC(O)CC2)C1 +Cc1nc(CC(=O)N2CCCC2CC(=O)c2ccccc2)cs1 +Cc1ccccc1NC(=O)c1ccc2snnc2c1 +CCCC(C)NC(=O)NC1CCOc2c(Cl)cccc21 +Cc1[nH]c2ncnn2c(=O)c1CCC(=O)Nc1cccc(Cl)c1 +CN(CCC(F)(F)F)C(=O)NC1CCCc2ccccc21 +COC1CCCC1OC(=O)CCC(=O)c1ccc(C)c(C)c1 +CCCNC(=O)C(C)NS(=O)(=O)c1ccc(N)nc1 +Cc1[nH]nc(-c2ccc(O)cc2O)c1Oc1ccccc1F +Cc1nc(NC(=O)CCN2C(=O)COc3ccccc32)sc1C +COC(=O)CNC(=O)C(N)c1cccc2cc[nH]c12 +CC(C)C(=O)NCCNC(=O)CC12CC3CC(CC(C3)C1)C2 +CNC(=O)C1(NC(=O)c2ccccc2Cl)CCCCC1 +C#CCN1CCN(CC(O)COCc2ccc3c(c2)OCO3)CC1 +Cn1nc(C(=O)NCc2ccco2)c2c1-c1ccccc1SC2 +CCOc1ccc(OCC(=O)NCC#Cc2ccccc2OC)cc1 +COC(=O)N1CCc2c(sc(NC(C)=O)c2C#N)C1 +CC(=O)NC(C)(C)Cc1ccc(O)c(Br)c1 +Cc1cc(CSc2ncccc2C(=O)NCC(C)C)no1 +CC(OCC1CCCO1)C(=O)N1CCc2cc(F)ccc2C1 +Cc1nc2ccccc2c(=O)n1NC(=O)COc1cccc(F)c1 +COc1ccccc1NC(=O)C(Sc1nnc(C)s1)C(C)C +CC(C)CNC(=O)C(C)Nc1ccc(CN2CCCC2=O)cc1 +Cc1ccc2nc(SCCN3CCOCC3)oc2c1 +Cc1cnn(-c2ccc(C(N)=O)cc2NCc2ccccn2)c1 +Cc1cc(C)n(CC(=O)NCC(=O)NC(C)(C)C)n1 +CC(=O)N1CCC(C(=O)NCc2c(C)cc(C)[nH]c2=O)CC1 +CCCN(CCc1ccccn1)C(=O)NCc1ccncc1 +O=C(Nc1nc(-c2ccccc2Cl)cs1)C1CCCO1 +COc1c(C)cc(S(=O)(=O)NC2CC2)cc1N +CCCOCc1ccccc1CNC(=O)N1CCCC(CO)C1 +COc1ccc(S(=O)(=O)NCc2ccco2)cc1 +Nc1cc(F)c(Oc2ccc3c(c2)CCC3)c(F)c1 +O=C(CC1C=CCC1)N1CCN(c2ccc(C(F)(F)F)cn2)CC1 +Cc1nc(NCc2ccco2)cc(-c2ccc(F)cc2)n1 +CN(Cc1ccccn1)C(=O)c1ccc2cc[nH]c2c1 +O=C(NCC1CN2CCCCC2CO1)c1cnccn1 +CCN(CC)C(=O)CSc1nncn1-c1cccc(NC(C)=O)c1 +Cc1nc(N)nc(C)c1CC(=O)N(C)Cc1cc(C(C)(C)C)n[nH]1 +COCCNc1ncnc(Nc2ccc(C(C)=O)cc2)c1N +C#CCNC(=O)N1CCN(C(=O)N2CCOCC2)CC1 +CCC(CO)NC(=O)NC1CC1c1cccc(Cl)c1 +CCOc1ccccc1NC(=O)NC1c2ccccc2CC1O +NC(=O)c1ccn(-c2cccc(Br)c2)n1 +O=C(c1ccc2[nH]ccc2c1)N1CCC(O)C1Cc1cccnc1 +CN1C(=O)NC(c2ccc3c(c2)OCO3)C2=C1COC2=O +CCN(Cc1ccccn1)C(=O)Nc1cc(-c2ncco2)ccc1C +COc1ccc2c(C(=O)N(C)Cc3cccc(F)c3)cc(=O)oc2c1 +Cc1noc(C2CCCN(C(=O)CCc3c(C)nn(C)c3C)C2)n1 +CCNc1nc(C)c(C(=O)N2CCn3nc(C(=O)OC)cc3C2)s1 +COc1ccc(NC(=O)Cc2ccon2)cc1N1CCCCC1=O +CC(C(=O)NCCc1cccs1)S(=O)(=O)c1ccccc1 +COc1ccc(S(=O)(=O)C2CCN(C(C)=O)CC2)cc1 +CCN(CCO)C(=O)c1[nH]c(C)c(C(=O)OC(C)C)c1C +CCN(CC1CCCO1)C(=O)c1nc(C)n(-c2ccc(Cl)cc2)n1 +Cc1ccc(S(=O)(=O)N2CCCC2C(=O)NCC(C)O)s1 +Cc1ccc(OS(=O)(=O)c2ccc3c(c2)n(C)c(=O)n3C)cc1 +CC(NC(=O)c1cnn(C(C)(C)C)c1)c1nc2ccccc2[nH]1 +Cc1c(Br)cnn1CC(=O)NCCCN1CCCC1=O +O=C1CC2(CCN(C(=O)C3CCCCC3)C2)Oc2ccccc21 +COc1cccc(C2CC2C(=O)NCCNC(=O)C2CCCCC2)c1 +O=C1NC(c2ccc(-n3cncn3)c(F)c2)Nc2ccccc21 +Cc1cc(C)n(-c2ccc(=O)n(CCNC(=O)C3CCC3)n2)n1 +Cn1cc(N2CC3(CCN(c4ncc(F)cn4)CC3)OCC2=O)cn1 +COc1ccccc1C(NC(=O)c1cn(CC(N)=O)nn1)C(C)(C)C +N#CCc1c(-c2cccs2)nc2scc(-c3cccnc3)n12 +COC(=O)c1nnn(Cc2cccc3ccccc23)c1N +Cc1cc(NC(=O)CNc2ccn(-c3ncccc3Cl)n2)on1 +O=C(N1CCC(O)CC1)C1(c2cccc(Cl)c2)CCCCC1 +CN1C(=O)C(C)(C)c2cc(Br)cnc21 +CC(=O)Nc1cccc(OCC(O)Cn2cnc3ccccc32)c1 +c1ccc(-n2nnnc2CN2CCc3ccccc32)cc1 +CCOCCC1(c2nc(-c3ccc(C#N)cn3)no2)CCC1 +CC(=O)c1cc(C(=O)NCCCn2ccc3ccccc32)n(C)c1 +CCc1noc(-c2csc(C(=O)NCCc3ccccn3)n2)n1 +Cc1noc(CNc2ccc(F)c(C(F)(F)F)c2)n1 +O=S(=O)(NCCc1c(F)cccc1F)c1ccc(F)cc1F +CC(C)c1ccc(CN2CCn3c(nn(C)c3=O)C2)cc1 +COc1c(O)ccc2c1C(C(NC(C)=O)C(C)C)NCC2 +COc1ccc(-c2cnnc(NC(C)Cc3cccnc3)n2)cc1 +CC(C)CCNC(=O)CCNC(=O)c1ccc(Br)cc1 +Cc1nnnn1C(Cc1cccc(F)c1)C(=O)N1CCCC(C)C1 +CCN(CC)C(=O)CN1CCCc2cc(Cl)ccc21 +CCc1ncc2c(n1)CN(C(=O)Cc1c(C)[nH]c3c(C)ccc(C)c13)C2 +CCOc1nc2ccccc2nc1N1CC(CO)C1 +CCOc1ccc(C(=O)Nc2ccc(Cl)cc2N)cc1 +Cc1nc2c(Nc3ccn(C)n3)nc(N)nc2n1C +Cc1nc(C)c(C(=O)NCCn2nc(-c3ccco3)ccc2=O)s1 +COc1cccc(OC)c1OCC(=O)NC1CCCCC1C +CCOc1ccc2nc(SCC(=O)N3CCCC3)sc2c1 +CC(C)NC(=O)CSc1ncc(-c2ccc(F)cc2)[nH]1 +CCOc1ccc(NC(=O)NCc2cnc(C)s2)c(C)c1 +Cc1ccc(C(C)C)c(OC(C)C(=O)NCc2ncn(C)n2)c1 +CC1CCCC(C(=O)Nc2cccc(-c3cn[nH]c3)c2)C1 +O=C(COC(=O)c1cc(Cl)ccc1Cl)Nc1ccc(O)cc1 +CC(C)CC(=O)NC1CC(=O)N(c2ccc(Cl)cc2)C1 +COc1ccc(C(C)=O)cc1CC(=O)Nc1ccccc1C +Cc1ccc(Cl)cc1NC(=O)NC1CCCc2c1cnn2CCO +CC(=O)c1nc2ccccc2n1Cc1ccc(N)nc1 +CC(C)c1csc(C(=O)N(CC2CCCO2)c2ccncc2)n1 +Cc1cnc(NCc2cnc3c(C)cccn23)s1 +CCc1c(C(=O)Nc2cnn(CC(=O)N(C)C)c2)[nH]c(C)c1C(C)=O +COc1ccc2cc(S(=O)(=O)n3ccnc3)ccc2c1 +N#Cc1ccc(Oc2cccc(N)c2)cc1Oc1cccc(N)c1 +CNC(=O)NCC(=O)N1CCC(c2nc(-c3ccccc3)no2)CC1 +CCCOc1ccc(CNC(=O)c2ccc(=O)n(C)c2)cc1 +CC(C)COCC1CN(C(=O)c2ncccn2)Cc2cncn2C1 +Cc1ccc(CNc2nccn(-c3cccc(F)c3)c2=O)cc1 +Cc1oc(C)c(C(=O)NCc2cccc(NC(=O)C3CC3)c2)c1C +O=c1c2ccsc2ncn1CC1CCCCO1 +Cn1cc(S(=O)(=O)NCc2nc(-c3ccccc3)cs2)cn1 +CC(C)CCNC(=O)c1cccc(N(C)S(C)(=O)=O)c1 +Cc1csc(NC(=O)CN2CCN(c3c(C)n[nH]c3C)CC2)n1 +N#CC1(NC(=O)COC(=O)c2n[nH]c(=O)c3ccccc23)CCCC1 +CCCC(C)NC(=O)CSc1nc2ccccc2c(=O)n1CC +CCN(CC)C(=O)CSc1ccc2c(c1)OCCCO2 +CCN1CCN(C(=O)c2cnc(SC)n2-c2ccccc2)CC1 +CCCC(=O)N1CCCN(C(=O)Nc2cc(C)nn2C)CC1 +CCc1nc2n(n1)CCCC2NCc1cc(OC)cc(OC)c1 +Cc1nc(C2CCCN(C(=O)Cn3c(=O)oc4ccccc43)C2)no1 +O=C(NCCc1ccccn1)N1CCN(C(=O)C2CCCO2)CC1 +O=C(NC1CCN(C(=O)c2ccncc2)CC1)Oc1ccccc1 +CCCNc1ccc(CSc2nc(C)cs2)cn1 +COC(=O)CC1CCCCN1C(=O)c1ccc(Br)cc1 +N#CC(NC(=O)Cc1cccc(F)c1)C1CCCCC1 +CCOC(=O)C(O)Cc1ccc(Br)cc1 +CC(C)Oc1cccc(C(C)NC(=O)Cn2ccccc2=O)c1 +Cn1nnc(-c2ccc(OCC(=O)N=c3[nH]cc[nH]3)cc2)n1 +O=C(NCc1nnnn1C1CCCCC1)Nc1ccccc1 +NC(=O)c1nn(-c2ccc(Br)cc2)c2c1CNCC2 +CCOCc1nc(N2CCCCC2)ncc1C(=O)OCC +COc1ccc(-c2nonc2NC(=O)c2ccco2)c(C)c1 +CCOc1ccc(OCC(=O)Nc2cccc(C)n2)cc1 +O=C(NCCNc1ncccn1)c1cc(F)cc(Br)c1 +Cc1noc(C(C)N2CCN(C(C)C(=O)Nc3cc(C)on3)CC2)n1 +Cc1nc(S(=O)(=O)NCCC(=O)N(C(C)C)C2CCC2)cn1C +Cc1ccccc1OS(=O)(=O)c1ccc(F)cc1 +Cc1cc(-c2cc3nc(C)c(C)c(NCc4cccnc4)n3n2)no1 +N#Cc1nnn(CC(O)CO)c1CCOc1ccccc1 +CC(=O)c1cccc(S(=O)(=O)NCCc2ccccc2F)c1 +N#Cc1cccc(NC(=O)CCSc2nncs2)c1 +O=C(CNC(=O)c1cc(Cl)c[nH]1)Nc1nccs1 +Cc1csc(NC(=O)CSc2ncnc(N)n2)n1 +O=C(CCCC(O)c1cc(F)ccc1F)N1CCCC1 +Cc1ccc(-c2cc(C(=O)N(C)Cc3ccncc3)on2)cc1 +CCN1CC(C(=O)N(C)Cc2ncc(C)c(OC)c2C)CCC1=O +COc1ccc(C(CC(=O)Nc2ccccc2C)NC(C)=O)cc1 +O=C(NC1CCOCC1)C1COC(=O)N1CC1CCOC1 +COc1cc(Cl)ccc1C(=O)N1CCNC(=O)CC1 +COc1ccc2c(c1OC)C(=O)OC2NC(C)(C)C +CCn1c(C)nnc1CS(=O)(=O)c1ncc(-c2ccccc2)n1C +O=C1c2ccccc2C(O)N1c1ccc(Br)cc1 +CC1CCCC(C)N1c1ncc(N)cc1Br +COc1cc(C(=O)OCC(=O)NCC(C)C)cc2c1OCCO2 +CN(CC(=O)NC1CCCC1)c1ccc(F)cc1 +COc1ccc(C(=O)N(C)Cc2nc3ccccc3s2)cc1 +O=C(COc1ccccc1CO)Nc1ccc(C(F)(F)F)cc1 +CC(C)c1nc(C2CCN(C(=O)Cc3cccs3)CC2)no1 +CCOc1ncnc2c1CN(Cc1nc(-c3cccs3)no1)CC2 +CCC(C)c1ccccc1OC(=O)C1CCOCC1 +Cc1ccc(C(=O)OCC2CCOc3ccccc32)c(=O)[nH]1 +O=C(NCCNC(=O)c1cc(Br)c[nH]1)c1ccccc1 +CN(Cc1cccnc1)C(=O)CCc1nc(Cc2ccccc2)no1 +Cc1nc(CN(C)c2nc3ccccc3nc2C)cs1 +Cc1cn(-c2ccc(CNC(=O)C3CCCCC3)cc2)cn1 +C#CCNC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +C=CCNC(=O)COc1ccc(C#N)cc1OCC +CNC(=O)COc1ccc2ccccc2c1Br +CC1CCCC(NC(=O)CCC(=O)NCc2ccccn2)C1C +CCOC(=O)c1c(C)c(C(=O)Nc2ccccc2F)c(C)n1C +O=C1CCCN1Cc1nnc(SCCOc2ccccc2)o1 +CCc1noc(CCCC(=O)NCc2cnn(C)c2)n1 +CNc1cc(-c2ccc(OC(C)C)cc2)nc(C)n1 +CCCn1c(C)cn2c3c(=O)n(CC(C)C)c(=O)n(C)c3nc12 +Cc1ccc(CCC(=O)NCc2ccnc(OC3CCC3)c2)cc1 +CCOCCC(=O)NC(C)c1cccc(N2CCCC2)c1 +CC(C)(C)C(=O)NCC(=O)OCc1csc(-c2ccccn2)n1 +COCCN(Cc1ccc(C#N)cc1)C(=O)C1CCCO1 +Cc1nc2ccc(NC(=O)N(C)CCc3ccccc3)cc2o1 +CN1C(=O)CCC(C(=O)NC2CCCC2)C1c1cccc(F)c1 +O=C(NCCO)NCCNC(=O)c1ccccc1 +COc1ccc(C(=O)CNC(=O)c2ccccc2C)cc1F +COc1ccc(C(C#N)NCc2ccccn2)cc1OC +CCOC(=O)c1c(NC(=O)Cn2cnnc2C#N)sc(C)c1CC +Cc1cccc(-c2nc(CNC(=O)C(C)(C)C)no2)c1 +CNc1nn2c(=O)c(Cc3ccc(OC)cc3OC)nnc2s1 +COC(=O)C1CN(Cc2cccc(N(C)C)c2)CC(C)O1 +CC(=O)Nc1ccc(NC(=O)CC(C)(C)C)cc1Cl +Cc1ccc(-n2nnnc2SCCn2cccn2)cc1 +N#CC(C(=O)C1(c2ccccc2F)CC1)c1ccc(C(F)(F)F)cn1 +Cc1cnn(C(C)C2CC2)c1NC(=O)c1ccccc1-n1cccn1 +O=C(NCc1ccc(F)cc1)c1cc(-c2ccccn2)[nH]n1 +CCOc1cccc(-c2ccc(C(C)(C)O)c(=O)n2C)c1 +COCC(C)NC(=O)NC(C)c1ccc(OC)c(Br)c1 +CN(Cc1cnn(C)c1)S(=O)(=O)c1cccc(OC(F)(F)F)c1 +O=C(c1ccc(-n2cnnn2)cc1)N1CCC2(CC1)OCCO2 +O=S(=O)(NCc1ccc(Cl)cc1Cl)c1ccc(O)cc1 +CCCCN(C)C(=O)Nc1c(C)cccc1C(=O)N1CCCC1 +COC(=O)C(C)NC(=O)c1csc2ccccc12 +Cc1cnc(N2CCN(C(=O)Nc3cccc(Cl)c3)CC2)s1 +COC(=O)c1sccc1S(=O)(=O)Nc1cccc(C#N)c1 +Cc1nc(CC(=O)N2CC3c4ccccc4OCC3(CO)C2)cs1 +O=C(NCCC1=CCCCC1)C1CN(C(=O)c2cnccn2)C1 +O=C(NCCn1cnc2ccccc21)c1cccnc1 +O=C(Cc1ccc(N2CCCC2=O)cc1)NC(c1ccccc1)C1CC1 +O=C(Nc1ccccc1-n1cncn1)c1cccc(Cl)c1Cl +COc1ccc(OC)c(NCCc2nccs2)c1 +N#Cc1cccc(CNC(=O)CCN2CCOC2=O)c1 +c1ccc(CSc2ncnc3c2oc2ccccc23)nc1 +CN(Cc1nc(-c2ccccc2)no1)C(=O)CC(C)(C)C +O=c1[nH]c(N2CCc3ccccc3C2)nnc1-c1ccccc1 +Cc1ccc(-c2nnc(C(C)N3CC(C)OC(C)C3)o2)cc1 +CC(C)(C)C(=O)NCc1ccc(C(=O)NCc2csc(=O)[nH]2)cc1 +NC(=O)COc1ccc(C(=O)NCCc2cccc3cccnc23)cc1 +Cc1ccc(C)c(NCc2cc(=O)n3c(C)csc3n2)c1 +CC(C)NC(=O)CN(C)S(=O)(=O)c1ccccc1F +O=C(c1cc2c(F)cccc2[nH]1)N1CCC(Oc2ccccc2)CC1 +Cc1ccnn1CCCNC(=O)c1c(N)cnn1C +COc1ccccc1CNc1c(F)cc(N)cc1F +O=C(Cn1ccnc1)Nc1ccnn1Cc1cnn(-c2ccccc2)c1 +NC(=O)C1CCN(C(=O)COC2CCCCC2)C1 +O=C(CNC(=O)c1ccc(F)cc1F)OCc1ccccc1Cl +COc1ccc2c(c1)OCC(CNC(=O)c1ccc3[nH]nnc3c1)C2 +CN(C)c1ccc(C(=O)NCCc2ccc(F)cc2)cn1 +N#CC1(NC(=O)C2Cc3ccccc3C(=O)O2)CCCCC1 +CN(Cc1cnn(C)c1)C(=O)c1cnn(-c2ccccc2)c1 +O=C(COc1ccccc1)NCCn1nc(-c2ccco2)ccc1=O +COc1cc(OC)cc(C(=O)NCCc2nc3ccccc3[nH]2)c1 +O=C(NCCCNC(=O)c1cnccn1)c1cccc(Cl)c1 +CCc1nnc(NC(=O)NCc2nnc3n2CCCCC3)s1 +O=C(C(c1ccccc1)c1ccccc1)N1CCN(CCO)CC1 +C=CCN(CC(F)(F)F)C(=O)c1cncc(Br)c1 +Cc1nc2nc3c(c(Nc4ccccc4)n2n1)CCCC3 +Cc1noc(C(C)NC(=O)Cc2nc(-c3ccccc3)oc2C)n1 +Cc1nnc(N2CCCC(S(=O)(=O)NC3CCCC3)C2)s1 +CNc1nc(-c2ccc(OC)c(OC)c2)c(C)cc1C#N +Cc1nc2ccc(C(=O)Nc3cccnc3)cc2nc1C +Nc1c(NCc2cccnc2)ncnc1NCC1CCCO1 +Cc1ccc2c(c1)[nH]c(=O)c1c(C(=O)NC3CCC(C)CC3)nnn12 +COc1cc(C)cc(C)c1C(=O)Cn1cc(N)cn1 +O=C(OCc1nnc(-c2ccccc2)o1)c1cnn(-c2ccccc2)n1 +N#CCc1ccccc1C(=O)OCc1ccc(F)cc1 +Cc1cccnc1CNC(=O)NCC(C)(C)c1ccncc1 +Cc1ccc(C)c2c1CCNC2C(O)c1ccccc1F +CNC(=O)NCC(=O)Nc1ccc(F)c(C#N)c1 +Cc1cc(C(C)NC(=O)N=c2[nH]cc(C)s2)c(C)o1 +CCOC(=O)C1(O)CCN(C(=O)NC2CC2)CC1 +Cc1ccc2cc(COC(=O)c3cccs3)c(=O)[nH]c2c1 +CC(C)CCNC(=O)C(c1ccccc1)n1cnnn1 +CCCc1sc(=NC(=O)c2sc(C)nc2C)[nH]c1C(=O)OC +Cc1nn(CC(C)C)c(C)c1CC(=O)Nc1ccn(C)n1 +Cn1nc2c(c1NC(=O)COc1ccccc1)CCC2 +Cc1ccc(N2CC(NC(=O)c3ccc4c(c3)OCO4)CC2=O)cc1 +COc1cccc(OCc2cc(N)ccc2Cl)c1 +O=C(NC1CC1)C1CC(c2ccccc2)CN(C(=O)C2CC2)C1 +COc1ccc(S(=O)(=O)N2CCOCC2)cc1OC +CCN(CC)C(=O)C1CCCN1C(=O)c1ccccc1OC(F)F +COc1ccccc1C(=O)NC(C(=O)Nc1cc(C)nn1C)C(C)C +COc1ccc(NC(=O)c2cc(S(C)(=O)=O)ccc2C)cc1 +Cc1ccc(NC(=O)NCCCn2cccn2)nc1 +CCCCn1nc(-c2ccc(CC)cc2)cc(CO)c1=O +CN(Cc1nc(-c2cccnc2)no1)C(=O)c1ccc(Cl)cc1O +CCCn1nc(C(=O)NCc2cccc(OC)c2)ccc1=O +CC(C)N(C(C)C)S(=O)(=O)c1ccc(NCc2ccccc2)nc1 +Cc1ccc(CNC(=O)NCC(=O)NCc2ccccc2C)cc1 +COc1cc(CNC(=O)CSc2ccccc2F)ccn1 +CC(=O)Nc1cc(NC(=O)N(C)CC(C)C)ccc1Cl +COc1ccc(OCCNC(=O)Nc2cnn(C)c2)cc1 +O=C(COCc1nc2ccccc2s1)Nc1nncs1 +CCCCc1nnc2sc(NC(=O)c3ccccc3)nn12 +CC(C)N(C(=O)CN1CCOC2CCCCC21)c1ccccc1 +CCn1cc(C(=O)Nc2cccc3[nH]cnc23)c(C(C)C)n1 +N#Cc1cc2c(n(Cc3ccccc3)c1=O)CCNC2 +Cc1cc(C)c(CN2CCOC(c3cccnc3)C2)c(-n2cccn2)c1 +C=CCn1c(C)nnc1SCC(=O)N(C)Cc1ccccc1C +Brc1cnc(C2CC2)nc1-c1cccnc1 +Cc1nc2ncnn2c(C)c1CCC(=O)N(CCC#N)CCC#N +CCCNC(=O)CNC(=O)NC(C)c1ccc(Br)cc1 +CC(OC(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1)C(N)=O +CC(NC(=O)N1CCOC(C#N)C1)c1cc2cc(Cl)ccc2o1 +COc1ccc(CC(=O)N(Cc2ccncc2)C2CC2)cc1 +CC(=O)c1ccc(OCC(=O)Nc2cc(-n3cccn3)ncn2)cc1 +CCOC(=O)C1=C(C(C)C)NC(=O)NC1c1sccc1C +COc1cc(CNC(=O)C(N)C(C)(C)C)ccc1O +O=C(NCCCO)c1ccn(-c2ccc(F)cc2)n1 +O=C(NCC1CCCO1)C1Cc2cc(Cl)ccc2O1 +NC(=O)NCCCCC(=O)N1CCCC1c1cccc(Cl)c1 +COc1ncccc1CNC(=O)Nc1cnn(-c2ccccc2F)c1 +Cc1ccc(S(=O)(=O)Nc2cc3[nH]c(=O)[nH]c3cc2C)cc1C +Cc1cc(NC(=O)c2cccn(Cc3cccc(F)c3)c2=O)no1 +CCc1cc(C(=O)N2CCCC2c2nc(CC)cc(=O)[nH]2)on1 +CSc1ccc(Cl)c(C(=O)Nc2ncc(C)s2)c1 +CS(=O)(=O)NC1CCCN(C(=O)Nc2ccc(CC#N)cc2)C1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)Nc1ccccc1Cl +O=c1oc(-c2cccnc2)nc2c(Cl)cccc12 +CC(C)c1nnc2n1CCN(C(=O)c1ccc(-n3cnnn3)cc1)C2 +Cc1n[nH]c(SCc2nc(N)c3c4c(sc3n2)CCCC4)n1 +Cc1cc(O)c(C(C)C)cc1NC(=O)Cc1ccon1 +CCOC(=O)CN(Cc1ccc(F)cc1)C(=O)C1CCC1 +Cc1noc(C)c1COc1ccc(C#N)cc1Cl +Cc1csc(NC(=O)c2oc3c(C)cccc3c2C)n1 +COC(=O)Cc1c(C)nc(-c2ccc(C)cc2)[nH]c1=O +NS(=O)(=O)CC1CCCN(C(=O)Cc2cccc(Cl)c2)C1 +Cc1cnc(C2NCCc3c(O)cc(O)cc32)cn1 +CC(O)c1ccccc1OCC(=O)N1CCOCC1 +CCNC(=O)c1snc(-c2ccc(F)cc2)c1N +COc1cccc(CNC(=O)c2cc(S(C)(=O)=O)ccc2C)c1 +CCC(=O)N1CCCC(C(=O)Oc2cccc(C(=O)NC3CC3)c2)C1 +CN(C(=O)c1cn(C)nc1C(C)(C)C)c1nccs1 +Cc1ccccc1N1CCN(C(=O)CCCn2cccn2)C(C)C1 +Cc1cccc(CNc2nc3nonc3nc2N2CCCC2)n1 +COc1ccccc1OCCNC(=O)c1ccc2c(c1)CCC2 +CNC(=O)c1ccnc(OC(C)(C)C)c1OC1CC1 +CC(Nc1cccc(F)c1)c1ccc2c(c1)OCCO2 +COc1ccnc(NC(=O)C2(c3ccc(Cl)cc3)CC2)c1 +CCN(CCn1cccn1)C(=O)Nc1cn(C)nn1 +O=C(NCC(=O)N1CCCC1)c1cc2ncccn2n1 +Cc1cccc(CC(=O)Nc2ccc(Cl)cn2)c1 +CC(NC(=O)NCC(O)C1CC1)c1ccc(-c2ccncc2)cc1 +O=C(NCC1Cc2ccccc2O1)NCC1COc2ccccc2O1 +Cn1cc(N)cc1C(=O)Nc1nc2c(s1)CCC2 +CC(CNC(=O)COc1ccc(Cl)cc1)CC1(C)OCCO1 +CCC(=O)NCC1CCCN(C(=O)Nc2ccccc2)C1 +Cc1ccc(NC(=O)c2nccnc2CO)cc1Cl +C=C(C)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1CC(=C)C +CC(=O)Nc1cnn(Cc2c(F)cccc2Cl)c1 +O=S(=O)(c1cccs1)N1CCN(C2CCCCC2)CC1 +COCc1cccc(CNC(=O)NCC(=O)N2CCCC2)c1 +O=C(Nc1ccccc1Cn1cccn1)C1CCC1 +O=C(Cc1ccc(F)cc1F)N1CCCC1CC(O)c1ccccc1 +Cc1nc(CCNc2ccc(F)c(Cl)c2)sc1C +CC(C)(C)NC(=O)CC1Oc2ccccc2NC1=O +CCOCC(=O)Nc1ccc(C(=O)Nc2ccccc2OC)cc1 +Cn1ncc(Br)c1C(=O)Nc1ccc(F)cc1F +COCCNC(=O)c1snc(C(=O)OC)c1N +COc1ccc(OC)c(COC(=O)CC(C)C)c1 +O=C(NCc1coc(-c2ccccc2)n1)c1cccc(-n2cncn2)c1 +COCCNC(=O)CCc1c(-c2ccccc2)nc2ccccn12 +CC(=O)Nc1ccc(CNC(=O)C2CCC(C(C)(C)C)CC2)cc1 +CC(C)(NC(=O)c1cccc(OCC(F)F)n1)c1nccs1 +CC(=O)Nc1cc(NC(=O)c2cccc(N(C)C)c2)ccc1Cl +Cc1cccc(NC(=O)C(NC(=O)c2ccc(Cl)cc2)C(C)C)n1 +COc1ccc(NC(=O)c2ccc(F)c(F)c2)cn1 +O=S(=O)(Nc1cnn(CCO)c1)c1ccc2c(c1)CCCC2 +O=C(NCc1cccc2ccccc12)c1cnc2sccn2c1=O +CN(Cc1ccc(O)cc1)C(=O)NCc1ccco1 +O=C(CCc1nc(-c2cccs2)no1)NCCO +CN1CCOC2CN(Cc3c[nH]nc3-c3cccs3)CC21 +CCn1c(C)cc(C(=O)N2CC(c3cccnc3)C2)c1C +O=C(c1ccoc1)N1CCCC(C(=O)N2CCCCC2)C1 +Cc1nc2c(N3CCC(CCn4cccn4)CC3)ncnc2o1 +CC1CN(C(=O)c2csc(COc3ccc(F)cc3)n2)CCO1 +O=C(c1ccno1)N1CCCn2c(nc(Cn3cncn3)cc2=O)C1 +COCc1nnc(SCc2nnc(C(F)(F)F)o2)n1N +Cc1nc(NCCNC(=O)C2CCCCC2)cc(N(C)C)n1 +C=CCOc1c(CN2CCCC(CN3CCOCC3)C2)c(C)nn1C +Cc1noc(C)c1CC(=O)NCc1ccc(NC(=O)C(C)C)cc1 +CN(CC(F)(F)F)C(=O)CSc1nnnn1C1CC1 +O=C(CSc1nncs1)Nc1ccc2c(c1)OCO2 +Cc1nn(C)c(C)c1C(=O)NCc1ccccc1OCC(F)(F)F +N#Cc1ccccc1OCC(=O)N1CCN(c2ccccc2F)CC1 +Cc1cc(F)ccc1S(=O)(=O)Nc1ccc(C#N)cc1 +COCCCNC(=O)c1nccc2c(F)ccc(N)c12 +COc1cc[nH]c(=NS(=O)(=O)c2ccc3ccccc3c2)c1 +Cc1ccc2sc(C(O)c3ccccc3)nc2c1 +CCN(C)C(=O)c1cc(S(=O)(=O)NCCOC)ccc1C +CCc1cccc(C)c1NC(=O)CCn1c(=O)oc2ccccc21 +Cc1ccc(S(=O)(=O)C(CNS(C)(=O)=O)c2ccco2)cc1 +CN(CCCOc1ccc(F)cc1)C(=O)NCc1ccnn1C +CCSc1ccc(Cl)cc1C(=O)NC(C)C(=O)NC(C)(C)C +Cc1ccc(C(=O)NCC(N)=O)cc1NC(=O)c1ccccc1 +CCS(=O)(=O)N1CCC(Nc2c(F)cc(C#N)cc2F)CC1 +N#CC(NC(=O)c1ccco1)c1cccc(Cl)c1 +OC1CCOCC1Cc1ccc(Cl)cc1Cl +CCn1cc(Br)cc1C(=O)NC(C)C(N)=O +O=C(Cc1cccc(F)c1)Nc1ccc(F)cc1F +CCCCC1C(=O)N(C)CCN1C(=O)CSc1ccccn1 +O=C(NCc1ccncc1)N1CCCCCC1c1ccncc1 +CCc1ccc(NC(=O)C(C)n2cc(Br)cn2)cc1 +CC(NC(=O)CCSc1ccc(Cl)cc1)c1ccncc1 +Cc1ccc(CN2C(=O)C(C)N(C)c3ccc(N)cc32)cc1 +FC(F)(F)c1cccc(OCc2nnnn2-c2ccccc2)c1 +O=C(c1cn[nH]n1)N1CCCCCC1c1ccncc1 +CCOC1CC(Nc2ncc(S(N)(=O)=O)s2)C12CCC2 +CC(CO)CNC(=O)Nc1cc(Cl)ccc1Cl +Fc1ccc(-c2n[nH]cc2CN2CCOC(c3nccs3)C2)cc1 +CCOC(=O)C1CCN(C(=O)CCn2cncn2)CC1 +CCc1onc(C)c1NC(=O)NCC(OC)c1ccccc1Cl +COc1cc(N2CCC(c3ccncc3)CC2)nc(N)n1 +Cc1cc(=O)oc2cc(OC(=O)C(C)Oc3ccccc3C#N)ccc12 +Cc1cccc(CC(=O)Nc2c(C)cccc2C)c1 +O=C(NCc1ccncc1)c1nc2c(o1)CN(Cc1ccccc1)C2 +CS(=O)(=O)c1ccc(N2CCCCC2)c(S(C)(=O)=O)c1 +Cc1cc(C)n(-c2nc(CCNC(=O)NC(C)C)cs2)n1 +COCCN(CCO)C(=O)Nc1ccccc1-n1nc(C)nc1C +Cc1ccc(NC(=O)N2CCCC2c2ccco2)cn1 +O=C(NCc1nc2ccccc2[nH]1)C1CC(=O)N(C2CCOCC2)C1 +Cc1ccc(F)c2c1N(C(=O)CCOCC(F)(F)F)CCC2 +CC(C)C(C)N(C(=O)c1c[nH]c2cccc(F)c12)C1CC1 +CCc1nnc(NC(=O)N(C)C(C)c2cc(F)ccc2F)s1 +CN(C)c1ccc(NC(=O)c2ccc(Cl)cc2F)nc1 +CNC(=O)CCNS(=O)(=O)c1ccc(Br)cc1F +CSc1ccc(OCc2nc(N)nc(N(C)C)n2)cc1 +CCC(C)N(CCOC)S(=O)(=O)c1ccccc1F +CC(=O)N1CCC(C(=O)Nc2ccc(F)cc2)(c2ccccc2)CC1 +COc1cc(C(=O)NC2CC2)c(-n2cccc2)cc1OC +CCn1c(=O)c2c(nc3n(C)c(C)cn23)n(C)c1=O +CCOC(=O)C(C)NS(=O)(=O)c1ccc(Cl)cc1F +COc1ccc(C(O)CNS(=O)(=O)N(C)C)cc1 +Cc1ccc(NC(=O)CS(=O)(=O)c2ccc(F)c(F)c2)cc1F +c1csc(CN2CCC(CN3CCOCC3)C2)c1 +COCCNc1nc(-c2ccc(F)c(C)c2)ccc1C#N +CNC(=O)COC(=O)c1cncc(Br)c1 +Cn1cc(Br)c(C(=O)Nc2ccc3c(c2)OCCO3)n1 +O=C(CCn1ncc2cc(Cl)ccc21)NC1CCCC1 +Cn1cc(CC(=O)NCCc2ccc(F)cc2)c2ccccc21 +Cc1cccc(NS(=O)(=O)c2ccc(F)cc2)c1 +CCCCN(CCO)C(=O)c1ccc2c(c1)OCC(=O)N2 +Cn1c(C(=O)Nc2ccc(CNC(N)=O)cc2)cc2ccccc21 +CC(=O)Nc1ccc(F)c(C(=O)NC(c2ccccc2)C2CC2)c1 +C=CCN(c1nccs1)S(=O)(=O)c1ccccc1 +CCCCNC(=O)CSc1nnc(C)n1-c1ccccc1 +COC(=O)c1ccc(CN(C)Cc2nc(C)c(C)o2)cc1 +CCCC(C)NC(=O)c1cccnc1N1CCCCC1 +N#CC1(NC(=O)CSc2nc3sccc3c(=O)[nH]2)CCCCC1 +COc1ccc(CNC(=O)NC(C)c2ccncc2)cc1O +Cc1ccc(C(=O)Nc2cc(S(=O)(=O)N(C)C)cc(C)c2C)cc1 +CCOC(=O)c1ccc(-c2ccc(N)cc2F)cc1 +Cc1ccc(C(=O)CCCC(=O)NC(C)C)cc1C +Cc1cc(C(C)NC(=O)C2COCCO2)c(C)o1 +Cc1cc(NC(=O)CN2CCN(C(C)CC#N)CC2)no1 +CC1OCCN(C(=O)c2scnc2C2CC2)C1C +N#CCc1cccc(C(=O)Nc2ccc(F)cc2)c1 +Nc1ccc(S(=O)(=O)NCC2(c3c(F)cccc3F)CC2)cc1 +O=C(NCCCC1CCCC1)NCc1cc(=O)[nH]c2ccccc12 +O=S1(=O)CC(Nc2nccs2)c2ccccc21 +COc1ccc2cc(CNC(=O)CNC(N)=O)ccc2c1 +Cc1ccc(Cc2nc(C(=O)NC(C)(C)C(=O)N(C)C)cs2)cc1 +CCn1ncc(-c2noc3nc(C4CC4)cc(C(=O)OC)c23)c1C +CNc1nc(CNC(=O)Nc2ccccc2C(F)(F)F)cs1 +CC(=O)Nc1cccc(C(C)NC(=O)c2ccccc2C(C)=O)c1 +COc1ccccc1C(=O)N1CCC(Oc2ccc(C#N)cn2)CC1 +Cc1nn(CC(C)C)c(C)c1CC(=O)N1CCCC1(C)C +OC1CCCOC12CCN(c1nnc3ccccn13)CC2 +O=C(CCc1ccc(-c2cccs2)o1)N1CCOCC(CO)C1 +O=S(=O)(Cc1ccon1)N(Cc1ccccc1)CC(F)F +CCN(Cc1cc2cccc(C)c2[nH]c1=O)C(=O)c1ccccc1F +COc1cc(C)ccc1NCC(=O)NC(C)C(C)C +COc1ccccc1C(=O)Nc1cnc2c(C)cccn2c1=O +Cn1ccnc1N1CCN(C(=O)c2ccc(Br)cc2)CC1 +Cc1noc(CCCC(=O)N(C)CCc2cccc3ccccc23)n1 +Cc1noc(C)c1S(=O)(=O)N1CCCC1c1nc(C2CC2)no1 +O=C(CO)N1CCc2[nH]nc(-c3cccc(F)c3)c2C1 +CCCCc1nnc(NC(=O)NCCc2cnn(C)c2)s1 +COc1c(C)cc(CNc2cccc(CN(C)C(C)=O)c2)cc1C +CC1CCN(C(=O)NCC2COc3ccccc3O2)CC1 +O=C(NCCOc1ncccc1Cl)c1cccs1 +COCCCNc1ncnc2c1[nH]c1ccccc12 +O=C(Cc1cccc(F)c1)Nc1ccc(NC(=O)C2CCCO2)cc1 +O=C(CCc1csc(NC(=O)NC2CCCCC2)n1)NC1CC1 +CC(C)c1ccccc1NCC(O)c1cccs1 +FC(F)(F)c1cc(Cl)ccc1NCc1ccncc1 +Fc1ccc(-c2nnc(COn3nnc4ccccc43)o2)cc1 +Cc1csc(C(=O)NCC#Cc2ccc(N(C)C)cc2)c1 +CCNS(=O)(=O)c1cccc(C(=O)Nc2cc(C)on2)c1 +COCC1c2nnn(CC3CC3)c2CCN1C(=O)c1cnoc1C +COCCOCC(=O)Nc1ccc(OC)c(C)c1 +Cc1nc2c(-c3ccccc3)nc(SCC#N)nc2s1 +NS(=O)(=O)CCNC(=O)c1ccc(Br)cc1O +CCCn1nc(-c2cc(F)ccc2OC)cc(CC#N)c1=O +COc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1C +CCOC(=O)c1cc(-c2c(O)cc(O)cc2O)nn1CCO +CCc1ccccc1NC(=O)COc1cccnc1N +CCc1noc(CC)c1CC(=O)N(CC)Cc1ccc2c(c1)OCO2 +Cc1nc(NC(=O)N2CCN(c3nc(C)c(C)s3)CC2)oc1C +COCCN(Cc1ccccn1)C(=O)c1c(O)cc(F)cc1F +Cc1csc(CN(C2CC2)S(=O)(=O)c2cccnc2)n1 +COC(=O)Cc1cc(=O)n(-c2ccc(C(=O)NC3CCCC3)cc2)[nH]1 +Nc1cc(C(=O)CCC(=O)NC2CC2)ccc1F +Cc1cc(C)n(C(=O)c2c(Cl)c(C(F)(F)F)nn2C)n1 +O=C(NC1CCCCC1)N1CCN(S(=O)(=O)C2CC2)CC1 +O=C(c1ccc(-c2nc(C3CCOC3)no2)cc1)N1CCOCC1 +CCNC(=O)c1ccc(-n2nc(C)cc2-c2ccccc2)cc1 +Cc1csc(=O)n1CC(=O)Nc1ccc(-c2ccccc2)cc1 +Cc1cccc(O)c1NC(=O)c1cccc(-n2ccnn2)c1 +O=C(Nc1ccc(OC(=O)c2cccc3cn[nH]c23)cc1)c1ccco1 +Cc1nc2nc(NC(=O)Cc3ccccc3)nn2c(C)c1Cl +COCCNC(=O)c1nc(-c2ccccc2)oc1C +CN1CCc2c(c(-c3cccnc3)nn2CC#N)C1 +N#Cc1cnc(NC(=O)c2cccc(Br)c2)s1 +CN(Cc1ccc(C(=O)NCC(F)(F)F)cc1)C(=O)C(C)(C)C +N#Cc1ccc(OCC(=O)N2CCOCC2)c(F)c1 +CCCNS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +COC(=O)c1ccc2c(c1)C(c1cncc(C)c1)NCC2 +C=C(C)Cn1c(C(C)NC(C)=O)nc2ccccc21 +C=CCNC(=O)Nc1ccc(NC(=O)CC2C=CCC2)cc1 +Cc1cc(N(C)C)nc(CNC(=O)c2ccccn2)n1 +COc1ccc(-n2nnnc2-c2cccc(N)c2)c(OC)c1 +CCC(NC(=O)c1ccc(F)c(COC)c1)c1nc2ccccc2[nH]1 +C#CCN1CCC(C(=O)N(C)CC(=O)NC2CC2)CC1 +CCCCN(C)C(=O)C1CCC(=O)N(CCc2ccccn2)C1 +COC(=O)C(c1cccc(C#N)c1)N(C)Cc1ccc(C#N)cc1 +CCCCC(=O)Nc1sc(C)c(C)c1C(=O)OC +CCc1ccc(-c2n[nH]c(SC(C)C(=O)NC)n2)cc1 +O=C(CS(=O)(=O)c1ccc(Cl)cc1)Nc1ccc(F)c(F)c1 +COC(=O)c1ccc(C(=O)N(CCC#N)CCC#N)s1 +COc1cccc(C(C)Nc2ncnc3[nH]ncc23)c1 +CC(=O)c1ccc(OC(=O)C(C)n2c(=O)oc3ccccc32)cc1 +CC(C)NC(=O)CN(C)C(=O)c1c(O)cc(F)cc1F +CN(CCCOc1ccccc1)C(=O)c1ccc(O)c(Cl)c1 +Cc1ccn2c(=NC(=O)CCc3nc4ccccc4s3)[nH]nc2c1 +CCOCCCNS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +Cc1cn2c(CN(C)C(=O)c3noc4c3CCCC4)c(C)nc2s1 +Cc1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccncc1 +Cc1cc(C(=O)OCC2CCC(=O)N2)c2c(C)nn(C)c2n1 +O=C(NCc1noc(CCc2ccccc2)n1)C1CCCC1 +O=C(NCCOCC1CCCO1)N1CCOCC1C1CC1 +Cc1ccc(OC(C)C(=O)Nc2ccc3[nH]c(=O)c(=O)[nH]c3c2)cc1 +COc1cc(-c2nc3c4cn[nH]c4ncn3n2)ccc1OC(F)F +CC1CC(C)CN(C(=O)CS(=O)(=O)c2ccc(F)cc2)C1 +CC(C)c1ncc(N(CCO)C(C)C)c(CO)n1 +CN(Cc1ccccc1N1CCCC1)C(=O)CNC(=O)C1CCCC1 +Cc1cc(C(=O)Nc2ncn(CC(=O)N3CCCCCC3)n2)no1 +COc1ccc(NC(=O)N2CCC(O)(c3nccn3C)CC2)cc1 +Cc1nc(NCCNC(=O)Nc2ccccc2)cc(N2CCCC2)n1 +Cc1cc(NC(=O)c2cnccn2)n(-c2nc3ccccc3s2)n1 +O=C(COC(=O)c1cccnc1N1CCCCC1)NC1CCCCC1 +O=C(c1cnccn1)N1CCC2CC(c3nnc(C4CC4)o3)OC2C1 +COc1ccc(C(=O)N2CCCC2)cc1NCc1ccccc1 +CCOc1ncccc1CNS(=O)(=O)c1ccc(C)c(C(N)=O)c1 +COc1ccc(S(=O)(=O)NC2CCCc3occc32)cc1OC +COCc1ccc(C(=O)Nc2cccc(NC(=O)NC(C)C)c2)cc1 +CCOC(=O)C1(NC(=O)Cn2nnc3ccccc3c2=O)CCCC1 +CN(C)C(=O)CC(Nc1nc2ccccc2s1)c1ccccc1 +Cc1ccc(Cl)cc1N1CCN(C(=O)CC#N)CC1 +Cc1nnc(SC(C)C(=O)NCc2ccccc2C)s1 +COCCNC(=O)Cn1cc(C(=O)OC)c2ccccc21 +COc1ccc(S(=O)(=O)NCCOc2ccccc2)cc1C +NC(=O)c1ccc(Oc2ccc(Br)cc2)nc1 +CC(COc1ccc(F)cc1)NC(=O)NC1CCOC1C +Cc1ccc(NCC(=O)N(C)CC(=O)NC(C)(C)C)cc1C +Cc1cc(C(=O)NC2CCc3nnc(C(C)C)n3C2)c(C)n1C(C)C +CCOc1cc(C)c(C(O)CNc2ccccc2C#N)cc1C +CCn1cncc1CN1CCc2nc(-c3ccncc3)[nH]c(=O)c2C1 +C=CCc1c(C)nc(Nc2nc(C)c3cc(OC)ccc3n2)[nH]c1=O +O=c1c2ccsc2ncn1Cc1csc(-c2cccs2)n1 +O=C(NCc1ccccc1Cl)c1cncc(Br)c1 +Nc1ncccc1COc1cccc2cccnc12 +Cc1nc2ccc(NC(=O)c3ccc4c(c3)CCC(=O)N4)cc2s1 +C=CCNC(=O)c1ccccc1NCc1noc(C(C)C)n1 +COC(=O)CS(=O)(=O)c1cc(C)c(Cl)cc1Cl +O=C(NCC(O)CN1CCOCC1)C1CCCOC1c1ccccc1 +Nc1ncnc(Nc2ccccc2Oc2ccccc2)n1 +Cc1ccc(-c2cc(C(=O)NCC3COc4ccccc4O3)[nH]n2)o1 +Cc1cccc(C(=O)Nc2cc(S(=O)(=O)NC3CC3)ccc2F)c1 +CCOCCS(=O)(=O)c1nncn1-c1ccccc1OC +NC(=O)COc1ccc(CNC(=O)Nc2ccccc2)cc1 +COc1c(F)cc(NC(=O)c2cccc(-n3cnnn3)c2)cc1F +Cc1nc(-c2cccc(CNC(=O)CCc3ccccc3C)c2)n[nH]1 +Cc1cc(Nc2ccccc2C(F)(F)F)ncn1 +Cc1cc(Br)c2ncc(C(C)O)n2c1 +CC(C)c1nc2cccc(F)c2n1Cc1cccc(N)c1 +O=C1CCC2(CCOC2)CN1Cc1cn2c(n1)SCC2 +Cc1cc(C(=O)Nc2ccccc2C(=O)N2CCCCC2)no1 +N#Cc1c(N2CCCC2)ncn(-c2ccccc2)c1=O +CC(c1ccco1)N(C(=O)NCC1(C(=O)N(C)C)CCCC1)C1CC1 +CC(C)OCc1cccc(NC(=O)N(C)Cc2cccc(C#N)c2)c1 +O=S(=O)(NCc1ccco1)c1ccccc1Cl +CCC(CC)C1CCN(C(=O)c2cc(S(N)(=O)=O)oc2C)C1 +N#Cc1cccc(N2CCC(CO)(Nc3ccccc3)CC2)n1 +COc1cc(CCC(=O)Nc2cc(OC)ccn2)cc(OC)c1 +Cc1ccc(-c2nccnc2CC2CCCN(S(C)(=O)=O)C2)cc1 +CN(CC(=O)Nc1ccc(-c2ncc[nH]2)cc1)S(C)(=O)=O +COc1cc(N)ccc1NC(=O)c1cc2ccccc2oc1=O +Cc1ccc(-c2c(-c3ccccn3)n[nH]c2N)cc1 +CCOCCC(=O)NC(C)c1cccc(N2CCCC2=O)c1 +CC(=O)NC(CC(=O)N(C)C)c1ccc(Cl)cc1 +Cc1ccc(C(C)(C)C)cc1S(=O)(=O)N(C)CCO +O=C(NCCS(=O)c1ccccc1)c1nc2ccccc2c(=O)[nH]1 +O=C(NCc1cn[nH]n1)c1cccc(-n2cccc2)c1 +CCN(Cc1ccccc1C)C(=O)c1ccccc1S(=O)(=O)CC +COC(=O)NC(C)C(=O)N1Cc2cnc(-c3ccccc3)nc2C1 +CC(C)OC(=O)Cn1c(C(C)NC(=O)C2CC2)nc2ccccc21 +CCCCNC(=O)NC(C)c1cnc(-c2ccncc2)nc1C +NC(=O)c1sc2nc(-c3ccsc3)ccc2c1N +COc1ccc2c(c1)OCC(O)(Cc1ccc(OC)c(OC)c1)C2O +CC(=O)N1CCc2ccc(NC(=O)c3ccco3)cc21 +CCNc1nnc(SCc2nnc(-c3cccs3)o2)s1 +OC1CN(c2nccc3occc23)CCC1c1ccc2c(c1)OCO2 +CC1CN(C(=O)Nc2cccc(Cl)c2)CCO1 +O=C(NCc1cccnc1-n1cccn1)C1CC(=O)N(C2CC2)C1 +Cn1nccc1C(=O)NCc1csc(C2CC2)n1 +CC(=O)Nc1ccc(-n2cc3c(=O)n(C)c(=O)n(C)c3c2)cc1 +Cc1occc1C(=O)N(c1cccc(O)c1)S(C)(=O)=O +CCn1nccc1C(=O)N=c1sc2c(OC)ccc(OC)c2n1C +CC1(C)CN(CC(=O)N2CCOC(c3ccc(F)cc3)C2)CCO1 +Cc1ccccc1NCCC(=O)c1ccc(F)c(N)c1 +CC(=O)NCCNC(=O)c1cccc(Oc2cnccn2)c1 +Fc1cnc(N2CCN3CC(OCC4CC4)CC3C2)nc1 +O=C(COc1nnc(-c2ccccc2)o1)NCCc1ccccc1 +C=CCn1c(SCC(O)c2c(F)cccc2F)nnc1C1CC1 +Cc1ccc(F)cc1-n1ccn(CC(=O)NC(C)C)c(=O)c1=O +CN(C(=O)c1ccc(NC(=O)c2ccccc2)cc1)c1ccnn1C +Cc1noc(C)c1CC(=O)N1CCc2[nH]nc(-c3ccccc3)c2C1 +Cc1cc(CCNC(=O)CNC(=O)OC(C)(C)C)on1 +Cc1ccccc1-n1nc(C(=O)N2CCC(C)C(O)C2)c2c1CCC2 +O=c1n(Cc2nn(-c3ccc(F)cc3)c3c2CCC3)nc2ccccn12 +COCc1cc(C(=O)Nc2ccc(OC)cc2OC)ccc1F +N#CCn1c(CCOc2ccccc2)nc2cc3c(cc21)OCO3 +CCCS(=O)(=O)NCc1ccc(OC)c(Br)c1 +COCC(C)(O)CNC(=O)c1ccccc1Cl +O=C(Cc1cc(-c2ccccc2)on1)Nc1ccon1 +O=C(NCCc1ccccc1)C1CC(=O)N(c2n[nH]c3ccccc23)C1 +O=C(NCCc1ccccc1)C1COC(=O)N1Cc1ccccn1 +CCc1nc(CNC(=O)c2c[nH]nc2-c2ccccc2Cl)cs1 +O=C(c1cc(NCCC2CC3C=CC2C3)ccn1)N1CCOCC1 +O=C(CC1(n2cccc2)CCCCC1)NCc1nc2ccccc2[nH]1 +CCN(Cc1ccco1)C(=O)CCNC(=O)c1ccc2cn[nH]c2c1 +CCCNC(=O)CN(C)C(=O)CSc1nc(C)c(C)o1 +NC(=O)C1Cc2ccccc2N(S(=O)(=O)c2cccs2)C1 +COCCC1NCCc2ccc(F)c(C(F)(F)F)c21 +CCC(C)n1ncc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1C1CC1 +CCCOc1ccc(C(=O)Nc2ccc(CC(=O)NC)cc2)cc1 +COCCC(=O)Nc1cc(C)c(Cl)cc1OC +COc1ccccc1C(=O)N(CC(C)O)C(C)(C)CO +COc1cccc(CCCNc2ccc(C(N)=O)cc2)c1O +Cn1c(C2CCCN2C(=O)c2n[nH]c3ccccc23)nc2ccccc21 +COc1ccc(C(=O)Nc2nnc(-c3ccncc3)o2)cc1OC +CCc1cccc(C)c1NC(=O)c1cnc(C)cn1 +CN(CCO)C(=O)COc1ccc(F)cc1Cl +COc1ccccc1CNC(=O)Cc1c(C)nc2nc(N)nn2c1C +O=C1CCC(C2NCCc3ccc4c(c32)OCCO4)N1 +CC1Cc2ccc(-c3cc(COC(=O)c4ccno4)no3)cc2O1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1ccc(F)cc1F +Cc1nc(C2CCCN(C(=O)c3ccccn3)C2)sc1C +CCOC(C)c1nc(C(=O)Nc2sc(C)c(CC)c2C#N)cs1 +CCOCCNC(=O)CNc1c(F)cccc1F +CNc1nc(-c2cc(C)n(Cc3ccco3)c2C)cs1 +COC(=O)Cn1cc(S(=O)(=O)N2CCCC2)cc1C(=O)OC +O=C(CCc1nnc2ccccn12)Nc1ccccc1N1CCCCC1 +COC(=O)C1(NC(=O)Cc2csc(-c3ccc(C)o3)n2)CCCC1 +Cc1noc(CCCNC(=O)Cc2nc(-c3cccs3)oc2C)n1 +COc1ccc2oc(C)c(C(=O)NCc3cc(C)oc3C)c2c1 +COC(=O)c1cc(N2CCNC(=O)CC2)ccc1N +Cc1cccc(Cl)c1NC(=O)Cn1c(=O)cnc2ccccc21 +CC(=O)c1cc2cc(C(=O)Nc3ccc(C)c(F)c3)cnc2[nH]1 +CCN(C)C(=O)Cc1csc(NC(=O)c2ccccc2F)n1 +Cc1cc(NC(=O)c2n[nH]c3c2CCc2ccccc2-3)no1 +Cc1ccc(F)cc1C(=O)NCC(=O)OC(C)(C)C +CNC(=O)c1cc(-c2ccccc2OCC2CCCO2)nc(N)n1 +Cc1nn(C)c2ncc(NC(=O)c3cnn(-c4ccncc4)c3C)cc12 +COC(=O)CNC(=O)C(C)Sc1nccn1C +COc1ccc(Cl)c(NC(=O)Cn2cnnn2)c1 +CCc1ccc(-c2ccc(CO)c(=O)n2CC)cc1 +O=C(OCCc1ccccc1)c1cccc(NC(=O)C2CCCO2)c1 +CCSc1nnc(CNC(=O)OC(C)(C)C)o1 +CCn1cc(C(=O)N2CCN(c3ccc(C#N)cc3F)CC2)cn1 +CC(=O)c1ccccc1NC(=O)c1ccn(-c2ccccc2)n1 +O=C(NCc1cccc(OCc2ccccn2)c1)c1ccncc1F +COc1ccc(C(O)C(C)NC(=O)C2CNC(=O)C2)cc1 +CCc1cnc(NCC2(N3CCOCC3)CCCCC2)nc1 +Cn1cc2ncn(CCNc3cccnc3)c(=O)c2n1 +Cc1c(Nc2cncnc2)c(=O)n(-c2ccccc2)n1C +COCCC(=O)NCc1cc2c(nc1OC)CN(C1CCCC1)C2=O +CN(C)C(=O)CC1(CC(=O)Nc2ccccc2Cl)CCCC1 +CNC(=O)c1ccc(CC2COc3ccccc3C2)cc1 +Cn1c2ccccc2c2cnn(CC(=O)NCc3ccco3)c(=O)c21 +CN(C)c1ccc(-c2nn(-c3ncccn3)c3c2CNCC3)cc1 +CCCC(=O)Nc1ccc(CNC(=O)c2ccc(C(C)=O)cc2)cc1 +Cc1ccc(C(N)=O)cc1NC(=O)Nc1ccc2c(c1)CC(=O)N2 +CCCc1cc(Sc2ccc(NC(C)=O)cc2)n2ncnc2n1 +O=C(CC1CCCC1)NCc1ccc2c(c1)OCO2 +CN(Cc1cccc(Cl)c1)C(=O)CC(NC(N)=O)c1ccccc1 +CCc1cc(NC(=O)N(C)C)ccc1OC(C)C +CC(C)(C)OC(=O)C1CC(O)CCN1C(=O)OC(C)(C)C +Cc1ccc(C)c(NC(=O)CN(C)C(=O)c2ccccn2)c1 +Cc1n[nH]c(C)c1NC(=O)CSc1ncc(-c2ccccc2)o1 +Cc1ncc(-c2nc(C3CCCCC3)cs2)c(N)n1 +Cc1nnc(NC(=O)NCc2cc(-c3ccccc3)on2)s1 +Cn1cnnc1C1CCCN(Cc2cccc(Cl)c2Cl)C1 +CN(Cc1cc(C(F)(F)F)ccc1F)Cc1cccn1C +Cc1ccc2[nH]c(C(=O)N3CCn4c(C)nnc4C3)cc2c1 +CCc1cnccc1C(=O)Nc1cccc(-c2nc(C)cc(=O)[nH]2)c1 +COc1ccc(NS(=O)(=O)c2c(C)cc(NC(C)=O)cc2C)cn1 +COCc1nnc(NC(=O)c2sc(-n3cccc3)nc2C)s1 +O=C(NC1(c2cccc(Br)c2)CCC1)c1ccncc1F +Cc1cc(C2CCC2)nc(NCc2cnn3ccccc23)n1 +CN(Cc1cc(Br)cs1)c1ccccc1CO +N#Cc1ccc(CNC(=O)N2CCCC(CO)C2)cc1 +O=C(Oc1ccccc1C(=O)N1CCOCC1)c1ccc(F)cc1 +Cc1nc(-c2cccc(CNC(=O)c3c(C)nn(C)c3C)c2)n[nH]1 +CC1Oc2ccc(C(O)CCCO)cc2N(C)C1=O +O=C(NCCCC(=O)N1CCc2ccccc21)c1nc2ccccn2n1 +Cc1cnc(NC(=O)CCNC(=O)c2ccco2)s1 +COc1ccccc1CN(Cc1cccnc1)C(=O)C1CCCO1 +CC(C)c1cc(C(=O)NCc2nnc3n2CCCCC3)n[nH]1 +C#CCN1CCC(C(=O)Nc2ccc(F)c(Cl)c2)CC1 +Cc1cccc(N2CCN(c3cc(C(F)(F)F)cnc3N)CC2)c1 +Cc1ccccc1CNc1ccc(C(F)(F)F)nc1 +Cc1cc(N)cc2c(CC(=O)N(CCO)CCO)noc12 +CCC(O)c1ccc2c(c1)C(NC(=O)CC(C)C)CCO2 +Cn1nccc1CNS(=O)(=O)CCc1ccccn1 +Cc1cccc(OCC(=O)N2CCC(c3nnc(C4CC4)o3)CC2)c1 +COC(C(=O)Oc1ccc(NC(=O)C2CC2)cc1)c1ccccc1 +CCNC(=O)NC1(C(=O)NC(Cc2ccccc2)C2CC2)CCCC1 +NC(=O)c1cccc(CNC(=O)N2CCCC(CO)C2)c1 +Cc1c(C(=O)N2CC3CC(O)C(O)CC3C2)sc2ccccc12 +Cc1ccc(N)cc1NC(=O)c1ccc(-n2cccc2)cc1 +CCOC(=O)c1nc(Cn2c(-c3ccccc3)noc2=O)cs1 +Cc1noc(C)c1CC(=O)Nc1nc(C(C)(C)C)cs1 +Cc1cc(C)c(CNC(=O)c2cc(-c3cccc(F)c3)no2)c(=O)[nH]1 +O=C(c1cccnc1)N1CCCC(c2n[nH]c(C3CC3)n2)C1 +O=C(Nc1ccc2c(c1)OCO2)Nc1nnc(-c2ccsc2)o1 +CCC(=O)NC1CCCN(C(=O)c2ccc(F)c(COC)c2)C1 +COc1ccc2c(c1)nc(CCO)n2Cc1ccc(N)nc1 +CC(=O)Nc1ccccc1OCc1noc(C(=O)N2CCOCC2)n1 +CCN(CC1CC1)C(=O)c1cc(C)c2c(=O)n(C)c(=O)n(C)c2n1 +CCOc1cc(NC(=O)c2cc(F)c(F)c(F)c2F)ccc1OC +COc1ccc(CN(C(=O)Cn2cnnn2)C(C)C2CC2)cc1 +CNC(=O)c1cccc(OC(=O)C(C)OCc2ccccc2)c1 +CCS(=O)(=O)N1CCC(C(=O)Nc2cc(F)ccc2OC)CC1 +O=C(NCC1CCN(c2ccc(F)cc2)C1)NCC1CCCO1 +CC1(C)COc2cnc(C(=O)Nc3ccc(F)cc3)cc21 +O=C(Cc1noc(Cc2ccc(Cl)cc2)n1)NC1CCCC1 +CCn1nc(-c2ccc(F)cc2)cc(CC#N)c1=O +CN(C)C(=O)CCNC(=O)c1c(Cl)ccc(Cl)c1Cl +O=S(=O)(c1cccs1)N1CCCC(CO)C1 +CCC(=O)c1cn(C)c2cccc(Br)c12 +COCc1nc(C2NC(=O)CN2CCC2CCCCC2)cs1 +CC(C)n1ccc(Cn2ccc(=O)c3sccc32)n1 +COc1cccc(C(=O)NCc2nccc(N(C)C)n2)c1 +Cc1cc(C(=O)N2CC3COCC3(c3nnc(C)o3)C2)on1 +Cc1ccccc1C1(C(=O)N2CCN(CCO)CC2)CCCCC1 +Cc1nc(SCC(=O)NCCC(C)(C)C)c2ccccc2n1 +CN(c1cccnn1)C1CCN(C(=O)Nc2ccc(F)cc2)CC1 +COc1c(C(=O)N2CC(C)CC(C)C2)nnn1Cc1ccccc1 +CSc1ccc(S(=O)(=O)NC(C)(C)C)cc1 +CCC(C)NC(=O)NCCCn1cnc2ccccc21 +Cc1noc(CC23COCC2CN(c2ncccn2)C3)n1 +CCOc1ccc(Cc2nc(CC(=O)NC3CCCC3)no2)cc1 +CNC(=O)C1CCCN(S(=O)(=O)c2ccc(C)cc2)C1 +COc1cc(OC)cc(C(=O)N(C)CC(O)C2CC2)c1 +CCCc1ccc(C(=O)C2CCN(S(C)(=O)=O)CC2)cc1 +O=C1c2cccc(Br)c2OCC12CC2 +O=C(NCC1CCCO1)c1cccc2c1-c1ccccc1C2=O +COc1ccc(C(=O)CN2C(=O)C(C)Oc3ccccc32)cc1 +CCN(C1CC1)S(=O)(=O)c1cncc(Br)c1 +O=C(c1cnc(C2CCCO2)s1)N1CCOC(c2ccco2)C1 +COc1cc(NC(=O)c2ccoc2C)cc(OC)c1OC +CN(Cc1nccn1C(F)F)C(=O)NCCc1nc2ccccc2[nH]1 +Cc1ncc(CNC(=O)CCn2c(C)csc2=O)s1 +COc1cc(C(C)=O)ccc1S(=O)(=O)C(F)F +Cc1cccc(C(=O)N2CCN(C(=O)C3CC3)CC2)n1 +CC(=O)Nc1c(C(=O)NC(C)C)cnn1-c1ccccc1 +O=c1[nH]ncc(NCCc2cccc3ccccc23)c1Cl +Cc1ccc(C(CNC(=O)NCc2cccnc2)N2CCOCC2)o1 +O=C(NCC1CN2CCCC2CO1)c1cc(Cl)ccc1Cl +CC(=O)N1CCc2ccc(NC(=O)c3ccno3)cc21 +CCOC(=O)CNC(=O)CSc1nc(C)c(C)c(=O)[nH]1 +O=C(Cc1ccc2c(c1)CCCC2)Nc1nncs1 +CCN(Cc1cc(-c2cc(OC)ccc2OC)on1)C(=O)C(C)C +Cc1n[nH]c(C)c1C1CCCCCN1C(=O)Nc1ccc(C#N)cc1 +CCCC1CN(c2ncccc2C#N)CC1NS(C)(=O)=O +CC(C)COC(=O)COc1ccc2ccc(=O)oc2c1 +Cn1nc(C(=O)Nc2ccc3c(c2)CCC3)c2ccccc2c1=O +CCC(=O)NCCS(=O)(=O)N1CCc2ccccc21 +CC(NC(=O)NCCCNS(C)(=O)=O)c1ccccc1Cl +COc1ccc(Cl)cc1NCc1ccsc1 +CCC1OCC2CN(C(=O)c3cc(C)nc(C)c3)CCC21 +Cn1cnc(CNC(=O)c2cc(Br)ccc2O)n1 +COC(=O)C(O)c1c(OC)cc(OC)cc1OC +Cc1cnc2c(S(=O)(=O)NCCc3ccccc3)cccc2c1 +CCc1cccc(C)c1NC(=O)CSc1nnc(C)n1N +CC1CCN(c2nc(C(N)c3cccs3)cs2)CC1 +COc1ccc(C2CC(=O)c3cnc(NC(C)=O)nc3C2)c(OC)c1 +Cc1cc(C(=O)NCc2csc(-c3ccccc3)n2)c(C)o1 +CC(C)c1ccc(S(=O)(=O)CC(=O)NC(C)c2ccccc2)cc1 +O=C(CSc1cc[nH]c(=O)n1)N1CCN(c2ccccc2)CC1 +CNS(=O)(=O)c1ccc(C(=O)NC(C)c2ccc(F)cc2)cc1 +COC(=O)C(C)CN(C)C(=O)c1cccc(OC)c1 +NC(=O)Nc1ccc(C(=O)OCc2cc(-c3ccccc3)on2)cc1 +COc1cccc(C(=O)NCc2ccc3c(c2)OCCO3)c1OC +CC(CC#N)Sc1ccccc1NC(=O)CN1CCCCCC1=O +Cc1cccc(NC(=O)c2ccc(-c3ccncc3)nc2N)c1 +CC(OC(=O)c1ccc2c(c1)OCCO2)C(=O)NCC1CCCCC1 +CCc1nc(C)c(C(=O)N2CCC(c3cc(=O)[nH]cn3)CC2)s1 +COCCNC(=O)C(C)Sc1nnc(-c2ccccc2F)n1C +Cc1cc(F)ccc1NC(=O)Cc1csc(-c2cccnc2)n1 +CS(=O)(=O)NCc1cn(Cc2ccccc2)nc1-c1ccccc1 +COCCN(Cc1ccccc1F)C(=O)c1cnn(C(C)C)c1 +Cn1cc(C2(C)CN(C(=O)Cc3ccc[nH]3)CCO2)cn1 +CC(=O)c1csc(NC(=O)c2ccc(C)c(Cl)c2)n1 +CC(=O)Oc1ccc(C2NCCc3ccc(O)c(C)c32)cc1 +O=C(c1cc(-c2ccco2)n[nH]1)N1CCC(Cn2cccn2)CC1 +O=C(c1cn(-c2ccccc2)nn1)N1CCCCC1 +COc1cccc(C(=O)OCc2nc(N)c3ccccc3n2)c1OC +COCCC(=O)c1ccc(OC)c(OC)c1OC +Cc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2-n2cncn2)cn1 +CN(Cc1ccc(F)cc1)S(=O)(=O)N1CCCCCC1 +Cc1cccc(OCC(C)NC(=O)Cc2c(C)nc(C)[nH]c2=O)c1 +CCCCn1c(=O)[nH]c(=O)c2c1nc(NCCCO)n2C +NC(=O)NCC(=O)NCCCSc1ccccc1 +CC(NC(=O)NC1CCC(O)CC1)c1cccc(N2CCCC2)c1 +CCc1ccsc1C(=O)Oc1cccc(S(C)(=O)=O)c1 +Cc1noc(C)c1S(=O)(=O)NCC1(CO)CC1 +COc1cccc(C(=O)Nc2cnn(C)c2C)c1OC +CC(Cn1cncn1)NC(=O)c1ccc(=O)n(C)c1 +COc1ccc(F)cc1NC(=O)C(C)NC(=O)c1ccco1 +Cc1c(C(=O)NC2CCCCC2)nnn1-c1ccc(Cl)cc1 +Cc1cc(N2CCOC(c3ccc(C(N)=O)cn3)C2)ncn1 +COc1cc(NC(=O)Cn2ccc3ccccc32)ncn1 +Cc1ccc(F)cc1NC(=O)COC(=O)COc1ccc(C#N)cc1 +CC(C)(C)c1csc(SCC(=O)Nc2ccncc2)n1 +O=C(Cn1cncn1)Nc1cc(N2CCCCC2)ncn1 +CCn1ccc2cc(S(=O)(=O)N3CCNCC3)ccc21 +CC1CC(N2CCOC(Cn3cncn3)C2)C(=O)O1 +O=C(CCc1cccnc1)N=c1[nH]nc2ccccn12 +CCN(Cc1ccco1)C(=O)c1cc(Cl)ccn1 +CCN(C)c1nc(-c2cccc(F)c2)c2c(N)n(C)nc2n1 +CC(=O)N1CCN(C(=O)CNc2cc(F)ccc2F)CC1 +CCC(=O)N1CCC2(CCCN(Cc3ccc(C(C)C)cc3)C2=O)C1 +O=C(NC1CC1)c1cc(=O)c(OCc2cccc(Cl)c2)c[nH]1 +Cc1ccc(NC(=O)NCc2ncoc2C)cc1C(N)=O +O=C(NCc1cccc(C(F)(F)F)c1)c1cccnc1 +COc1ccc(CC(=O)NCc2nnc(-c3scnc3C)o2)cc1 +O=C(Nc1c(O)cccc1F)c1cccc(Cl)c1 +CCc1nc(CN2CCN(C(=O)NC(C)C)CC2)cs1 +Cc1cn(S(=O)(=O)c2cc(Cl)c(Cl)cc2C)cn1 +N#CC(C(=O)CCc1ccc(Cl)cc1)c1ccccn1 +Cc1cccc(Cl)c1NC(=O)Nc1cccnc1 +CC(C)C(=O)N(C)CC(=O)Nc1ccc(Oc2ccccc2)nc1 +CCN(CC)C(=O)CNc1cccc(NC(=O)c2ccccc2)c1 +Fc1ccc(-c2cnnn2-c2nonc2-n2cccc2)cc1 +COc1ccc(-c2cc(CNC(=O)c3cccn(C)c3=O)no2)cc1 +c1ccc(-c2csc(CNc3cn[nH]c3)c2)cc1 +CCN1C(=O)C(C)(C)c2cc(S(=O)(=O)NC)cc(C)c21 +CC(CCC1CCCC1)NS(=O)(=O)c1cnn(C)c1 +CC1CN2CCCC2CN1S(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +CN(C)c1ccc(NC(=O)C2(c3ccccc3)CCOCC2)nc1 +Cc1nnc2c(NCc3ccc(OC(C)C)c(F)c3)nccn12 +CCOC(=O)c1c(C)nc(N)nc1-c1cccs1 +CC(C)(C)c1noc(CCC(=O)Nc2cn[nH]c2)n1 +Nc1cc(C(=O)CCNc2ccc(Cl)cc2)ccc1F +O=C(NCCCO)c1cn(Cc2ccccc2)nc1-c1cccs1 +CN(CCN1CCCC1=O)C(=O)NCc1ccco1 +CC(=C(C(O)C(C)(C)C)n1cncn1)c1ccc(Cl)cc1 +CN(C)S(=O)(=O)NCCN1CCCc2ccccc21 +Brc1ccc(OCC2CCCCO2)nc1 +COc1ccc(NC(=O)Cn2cnc3sc(C)c(C)c3c2=O)cc1 +COC(=O)C(CNC(=O)Nc1cnccc1C)Cc1ccccc1C +CC1CC(OC(=O)c2ccc(CN3CC(C)OC(C)C3)cc2)C(=O)O1 +CNC(=O)NCC(=O)Nc1ccc(Br)c(C)c1 +COC(=O)CCC(=O)Nc1cccc(-n2ccnc2)c1 +COc1ccccc1NC(=O)Nc1nn(C)c2cccc(N(C)C)c12 +CC(C)c1noc(COC2CCN(C(=O)Cc3cccs3)CC2)n1 +Cc1cc(NC(=O)CSc2nnc(-c3cccs3)n2N)no1 +FC(F)(F)CNCCSc1ccc(C(F)(F)F)cn1 +CCOCC1COCCC12CCN(C(=O)CCc1ccccc1)CC2 +COc1cc2cc(C#N)c(N3CCOC(C)C3)nc2cc1Cl +CCn1c(=O)[nH]c2cc(C(=O)N3CCOC(C)(C)C3)ccc2c1=O +CCCn1c(C)nnc1SC(C)C(=O)c1[nH]c(C)c(C(C)=O)c1C +COc1cccc(OC)c1C(=O)N(C)C(C#N)c1ccccn1 +CC(C)COCCC(=O)Nc1ccccc1NC(=O)N1CCCC1 +CC(NS(C)(=O)=O)C(=O)NC1CCC(c2ccccc2)CC1 +O=C(NCc1ccco1)C1CCc2ccccc2N1 +CCC(CC)c1nnc(NC(=O)CCC(=O)N2CCOCC2)s1 +CN(C)S(=O)(=O)c1ccc(NCC2CCCO2)nc1 +CC(C)CN1CCOC(COC(=O)c2ccc(-n3ccnn3)cc2)C1 +COc1ccc(C)cc1NC(=O)c1ccc2ccccc2n1 +O=C1CCCc2cc(-c3csc(NC4CC4)n3)ccc2N1 +O=c1[nH]c(=O)n(S(=O)(=O)c2ccc(F)cc2)cc1F +CCn1cc(CC(=O)NCC2CCCCC2)c2cccnc21 +Cc1noc(C)c1-c1nc(CSc2n[nH]c(=O)n2C2CC2)no1 +CCC(=O)Nc1ccc(NC(=O)NC(CO)c2ccccc2)cc1 +COc1ccc(C2NC(=O)c3cc(Cl)ccc3N2)cc1O +O=C(CCn1cncn1)NC1CCCc2ccccc21 +CCn1cnnc1CNC(=O)N(C)Cc1cnn(C)c1 +COC(=O)c1cc(C(C)C(C)C)nn1-c1ccccn1 +Cc1cccc(N)c1C(=O)Nc1cccc(Br)c1 +CN(Cc1ccco1)C(=O)c1cc(N)ccc1Cl +CCOc1nnc(CN2CCN(c3ccc4nncn4n3)CC2)s1 +Cc1cc(CC(=O)N2CCN(S(=O)(=O)c3ccccc3)CC2)on1 +CNC(=O)C(C)NC(=O)c1cc(N)c(F)cc1Br +Cc1occc1-c1nnc(SCc2ccc(C#N)cc2)n1C +O=C(CSc1cccs1)NCc1cccc(NC(=O)C2CC2)c1 +CCC(C)C(NC(=O)C1CC1c1ccccc1C(F)(F)F)C(N)=O +CC1(CO)CCCC1Nc1ccc2nnc(C3CC3)n2n1 +Cc1cccc(C(=O)Nc2ccnn2C(C)C)c1O +COc1cc2c(cc1O)CCNC2C(=O)c1cccs1 +Cc1ccoc1C(=O)N1CCOC2C(Oc3ncccc3F)CCC21 +NC1=NC(=O)C2(CCN(S(=O)(=O)NCc3ccccc3)CC2)N1 +CC(C)(C)OC(=O)CCN1CCN(c2ccccc2O)CC1 +Cc1cnc(NC(=O)c2cc(-c3ccco3)on2)s1 +CCC(CC)C(=O)N(C)Cc1ncc(C)c(OC)c1C +NC(=O)C(NC(=O)COc1ccccc1)c1ccccc1 +CN(C)c1nc(N)nc(CSc2ncnc3c2cnn3C)n1 +Cc1ccc(C(=O)CNC(=O)c2ccccc2C)cc1C +CC(=O)Nc1nc(CC(=O)Nc2cccc(Cl)c2C)cs1 +CCNC(=O)C1CN(C(=O)C(C)Sc2ccccc2Cl)C1 +O=C(Cn1ccnc1)N1CCN(c2ccccc2)CC1 +CCC(C)(C)NC(=O)c1ccc(NC(=O)Cn2cnnn2)cc1 +CC(C)C(NC(=O)Cn1c(=O)cnc2ccccc21)c1ccccc1 +Cc1ccccc1-c1nc(C(=O)N2CCC(O)C2)cs1 +c1cncc(CN2CCCC(c3noc(C4CC4)n3)C2)c1 +Cc1nc(NC(=O)CSc2ccc(F)cc2)sc1C +COc1ccc2nc(C)c(C(=O)N3CCC4(CC3)OCCO4)cc2c1 +CC(NC(=O)N(C)C(C)C)c1nnnn1-c1ccccc1 +CC1(C)C(=O)NCCN1Cc1cc(F)cc(F)c1 +CCN(CC)C(=O)CN(C)C(=O)Cn1c(=O)cnc2ccccc21 +CCCCN(CC)C(=O)c1ccccc1S(=O)(=O)CC +CC1CCC(NC(=O)NCCCOCc2ccco2)CC1 +CC1(C)COCCN1C(=O)CCc1nc(-c2ccncc2)no1 +CCn1c(C)nc2cc(C(=O)Nc3ccccc3)ccc21 +Cc1ccncc1NC(=O)N1CCCC(CC(C)C)C1 +N#CCCN(Cc1ccccn1)C(=O)c1cnc2ccccc2n1 +Cc1ccc(NC(=O)c2cc(C)[nH]c(=O)n2)c(O)c1 +CC(C)(C)C(=O)CNC(=O)Cc1ccc(F)cc1 +CCOCc1ccccc1NC(=O)N1CCC(O)(C(F)(F)F)C1 +CNS(=O)(=O)c1cccc(CNC(=O)c2cc(C)on2)c1 +O=C(CC12CC3CC(CC(C3)C1)C2)NCCN1CCOCC1 +CCOc1ccccc1NC(=O)CCSc1ccccn1 +NS(=O)(=O)c1cccc(NC(=O)c2cc3cc(F)ccc3o2)c1 +COC(C)C(=O)N1CCN(C(=O)c2c(F)cccc2Cl)CC1 +COCCn1cc2c(n1)C(NC(=O)c1ccccc1)CCC2 +CC(C)(C)C(=O)Nc1cnn(Cc2ncc(-c3ccccc3)o2)c1 +O=c1[nH]c2cc3c(cc2cc1CNc1ccc2c(c1)CCC2)OCCO3 +CCCCNC(=O)c1c(Cl)ccc(S(=O)(=O)CC)c1Cl +OC(CNc1ccc(F)c(Cl)c1)c1ccc2c(c1)OCO2 +O=C1CN(c2ncnc3[nH]cnc23)CCN1C1CCCCC1 +COc1ccc(CN2CCN(Cc3nc4ccccc4[nH]3)CC2)cn1 +O=C(COC1CCCC1)NCCNC(=O)c1ccoc1 +N#CC1(C(=O)N2CCN(Cc3cccnc3)CC2)CCCCC1 +CCN1C(=O)COc2cc(-c3noc(C(=O)NC4CC4)n3)ccc21 +Cc1nnc(CN(Cc2nnnn2C2CC2)C(C)(C)C)o1 +CSc1cc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)ccn1 +O=C(c1cnc2ccccc2n1)N1CCC(c2n[nH]c(C3CC3)n2)CC1 +Cc1ccc2c(c1)nc(CC#N)n2Cc1ccc(C#N)cc1 +COc1ccccc1CN(C(=O)NCc1cccc(C#N)c1)C1CC1 +CCc1ccnc(NS(=O)(=O)c2c(C)noc2C)c1 +CCOC(=O)c1nc(-c2ccccc2)oc1C(=O)OCC +CCCN(CC1CC1)S(=O)(=O)c1cn(C)c(=O)n(C)c1=O +COCC(=O)Nc1cccc(NC(=O)N(C)CC2CCCC2)c1 +Cc1cccc(C)c1OCCN1CCCS1(=O)=O +COc1ccc(-c2nnc(SCc3nc(C)c(C)s3)o2)cc1 +Cn1ncc(Cl)c1C(=O)Nc1ccc(Br)cc1 +Cn1c(C2CC2)nc2cc(NC(=O)Nc3cccc(C#N)c3)ccc21 +COCCNc1ncnc2c1c(C)c(C)n2-c1ccc(F)c(F)c1 +O=C1NCC(=O)N2CCN(C(=O)CCc3c[nH]c4ccccc34)CC12 +CCOc1ccccc1NC(=O)COC(=O)c1ccsc1 +CCC(C)NC(=O)c1ccc2c(c1)N(C)C(=O)C(C)O2 +C=CCNC(=O)c1ccc(NC2CCOC2c2ccccc2)nc1 +Cc1n[nH]c(C)c1NC(=O)C1Cc2ccccc2S1 +CCCS(=O)(=O)N1CCCC1C(=O)c1ccc(C)c(C)c1 +CCc1c(C#N)nnn1-c1cccc(NC(C)=O)c1 +Cc1[nH]c(=O)c(C(=O)NCCc2nncn2C)cc1Br +CN(c1ncnc2cc(F)c(F)cc12)C(CCO)c1ccccc1 +CCOC(=O)CCC(=O)Nc1ccc(C)c(N2CCCCC2=O)c1 +COC(=O)c1cc(C(=O)Nc2ccccc2OC)c(=O)[nH]c1C +Nc1ccc2c(c1)N=C(N1CCCc3ccccc31)CO2 +Cc1ccc(C)n1-c1nc2ccc(C(=O)N3CCCCC3)cc2s1 +Cc1ccc(C)c(C(C)NC(=O)c2ccc(-n3ccnc3)nn2)c1 +CCCC(=O)NCC(=O)OCC(=O)N1c2ccccc2CC1C +O=C(Nc1cc(Cl)ccc1-n1cncn1)c1cccs1 +O=C(CSc1ccc2ccccc2c1)NCc1cscn1 +Cc1cc(C(=O)Nc2cccc(-c3cnco3)c2)c2c(C)nn(C)c2n1 +CC(C)C1CN(C(=O)c2ccc3[nH]nnc3c2)CC1NC(=O)N(C)C +COC(=O)c1ncoc1-c1ccccc1C(=O)N1CCOCC1 +CC(=O)Nc1ccc(C2(C(=O)NCc3ccccc3C)CCC2)cc1 +Cc1ccc(OCc2csc(-c3cnn(C)c3)n2)cc1 +O=C(NCCc1ccccc1Cl)NCc1ccsc1 +Cc1ccc(-n2nnc(CO)c2-c2cccnc2)cc1 +Cc1cnc(NC(=O)C2(c3cc(-c4cccs4)on3)CC2)s1 +Cn1cc(CCC(=O)Nc2cccnc2N2CCCCC2)cn1 +CS(=O)(=O)NC1CCCN(C(=O)c2ccc3[nH]cnc3c2)C1 +CCS(=O)(=O)NCCNC(=O)NCc1ccccn1 +Fc1cccc(-c2nnc3sc(C4CC4)nn23)c1 +C=CCN(C(=O)c1c[nH]c2ncccc12)C1CCCC1 +Cc1cc(C(=O)OCc2ccccc2C#N)c(C)n1CC(F)(F)F +CC1CCCN(C(=O)C2CCN(c3ccc(C#N)cn3)CC2)C1 +CCCN(Cc1ccccc1)C(=O)c1ccc[nH]c1=O +O=C(Cc1ccc(F)cc1)Nc1ccn(-c2ncccc2Cl)n1 +Cc1ccc(-c2nnc(Cn3cc(Cl)cn3)o2)cc1 +Cc1nccn1-c1ccc(NC(=O)CC(C)(C)c2ccccc2)cn1 +O=C(Cn1ncc2ccccc2c1=O)NCCc1cccs1 +CC(C)n1nnc(CO)c1COc1ccc(Cl)cc1Cl +Cc1cnc(N2CCCn3c(nnc3Cn3cccn3)C2)nc1 +C=C(C)CN(CC)S(=O)(=O)c1ccc(S(=O)(=O)NC)cc1 +CSc1nc(NC(=O)CCc2ccc(F)cc2)n[nH]1 +CC(=O)c1csc(NC(=O)C2CC(=O)N(C)C2c2cccnc2)n1 +Cc1ccc2c(C)c(C(=O)NCCc3cscn3)oc2c1 +c1cnc(Nc2cc(C3CCCN(c4ncccn4)C3)ccn2)nc1 +CC(=O)c1ccc(S(=O)(=O)NCC2CCCc3ccccc32)cc1 +COc1cccc(NC(=O)Cc2ccccc2C)c1 +CNC(=O)CN1C(=O)COc2cc(CO)ccc21 +CC(Cc1nnc(SCC(=O)c2cnn(C)c2)o1)c1ccccc1 +COc1ccnc(Cn2c(=O)c(C)nc3ccccc32)c1OC +CCCC(=O)c1ccc2c(c1)N(C(C)C(=O)OC)C(=O)C(C)O2 +c1ccc(Nc2nc3nonc3nc2N2CCOCC2)cc1 +COc1cc(CO)cc2c1OC(C)C(=O)N2CCO +CCN(CC)C(=O)CCC(=O)N1CCCC(C)(c2ccccc2)C1 +COCCN(C)C(=O)NC(C)Cc1ccc(O)cc1 +Cc1ccc(C(N)=O)cc1OCC(=O)NCCc1c(F)cccc1F +CCC(NC(=O)N1Cc2ccccc2N(C)CC1C)c1nccs1 +CC(CC#N)N(C)C(=O)Nc1cc(Cl)ccc1N(C)C +CC1=C(c2ccc(C)c(C)c2)S(=O)(=O)N=C1N1CCN(C)CC1 +Cc1ccc(C)c(CC(=O)NCCNC(=O)c2cccnc2)c1 +CCCN(CCC)C(=O)c1cccc(C(=O)Nc2ncc(C)s2)c1 +Cc1n[nH]c(C)c1NC(=O)C1CC(=O)N(C2CCC(C)CC2)C1 +O=C(COc1ccc(Cl)cc1Cl)Nc1nnc(C2CC2)s1 +CC1CN(CC(O)CN(C)Cc2ccsc2)CC(C)O1 +Cn1ncc(Cl)c1C(=O)N1CCN(c2cccc(Cl)c2)CC1 +CN(Cc1cccc(-n2cccn2)c1)C(=O)c1ccnc(N)c1 +Cc1ccccc1CNC(=O)Nc1ccc(C)c(C(=O)NC(C)C)c1 +COC(=O)CCc1csc(COc2ccc(Cl)cc2)n1 +O=C(Cn1cnnn1)Nc1cccc(CN2CCOCC2)c1 +O=C(NCC1CCCO1)c1cnc(N2CCCCC2)c2ccccc12 +COc1ccccc1CNC(=O)CCc1nc2ccccc2[nH]c1=O +O=C(NC1CCc2c(O)cccc21)c1ccc(F)cc1F +O=C(NCCc1cn2ccccc2n1)c1c[nH]nc1-c1ccccc1F +N#CC1(NC(=O)Cc2csc3nc(-c4ccc(F)cc4)cn23)CC1 +CCn1ccc(CN(C)S(=O)(=O)c2cc(C)ccc2C)n1 +CCCC(=O)N(CCn1cccn1)c1nc2ccc(OC)cc2s1 +CCc1noc(CC)c1CNC(=O)NCCc1cccnc1 +N#Cc1nnn(-c2ccc(Cl)cc2)c1-c1ccccc1 +Cc1n[nH]c(C)c1NC(=O)CN1CCOC(CNc2cccnn2)C1 +O=C(CNc1ccccc1Br)N1CCCCCC1 +NC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 +Cc1cc(C(=O)Nc2cccc(Cl)c2C)no1 +CCN(CC1CC1)C(=O)NC(C)c1ccc(-n2ccnc2C)cc1 +COc1cc(NC(=O)N2CCc3sccc3C2)ccc1NC(C)=O +CCc1c(C(=O)CNc2cccc(F)c2F)[nH]c(C)c1C(C)=O +CCCC(=O)Nc1cccc(NC(=O)NCCO)c1C +CC(=O)NCCNC(=O)c1csc(Cc2ccccc2)n1 +Fc1cccc(Cn2nnc(-c3ccsc3)n2)c1F +O=C(Nc1ccccc1OC(F)(F)F)c1ccoc1 +CC(Oc1ccccc1)C(=O)Nc1ccc2c(c1)CC(=O)N2 +CC(C)CCN(CCC#N)Cc1cccc2[nH]ccc12 +Cc1ccc(CCNC(=O)NC(C)C(C)CO)c(C)c1 +Cc1n[nH]c2c(NCCc3ccc(F)cc3)ncnc12 +N#Cc1ccc(NC2c3ncccc3C(=O)N2c2ccccc2)cc1 +Cc1ccc(N2CCC(NC(=O)Cc3cccc(F)c3F)C2=O)cc1 +CCCNS(=O)(=O)c1ccc(NS(=O)(=O)N(C)C)cc1 +O=C(NCc1cccc(F)c1)c1ccc(-c2ccco2)[nH]c1=O +CCCc1nnc(NC(=O)CNc2cccc(C)c2)s1 +CC(C(=O)Nc1cccc(-c2nc(C3CC3)n[nH]2)c1)c1cccs1 +COCCN1C(=O)CC2C1CCN2C(=O)Nc1cccc(OC)c1 +CCn1nc(C(=O)Nc2ccc3c(c2)CCC3)c2ccccc2c1=O +CCNC(=O)Cn1cnc2c(c(C)c(C)n2-c2ccccc2)c1=O +O=C(NCc1ccc(C(=O)N2CCCCCC2)cc1)c1cnccn1 +CCS(=O)(=O)N1CCN(C(=O)c2ccc3c(c2)OCCO3)CC1 +Cn1c(=O)ccn(CC(=O)Oc2ccc(C(F)(F)F)cc2)c1=O +COc1ccc(OCc2nnc(C)n2C)c(CO)c1 +CC(C)C(C)NC(=O)c1cc(S(=O)(=O)N(C)C)ccc1Cl +O=C(NCCSc1ncc(-c2ccccc2)[nH]1)c1cccc(F)c1 +CCc1cnccc1C(=O)NC(C)c1cccc(-n2cncn2)c1 +Cc1ccc(-c2nnc(S(=O)CC(=O)N3CCCCC3)n2C)cc1 +CCC(=O)N1CCCC(C(=O)N2Cc3nc(C)n(C)c(=O)c3C2)C1 +Cn1c(SCCCO)nc2ccsc2c1=O +COCCNC(=O)N1CCN(CC(=O)c2cccs2)CC1 +O=C(c1cc(-c2ccccc2)no1)N1CCc2c(nc[nH]c2=O)C1 +Cc1cnn(Cc2cc(Cl)c3c(c2)OCCO3)c1N +CCN(Cc1cccc(C)c1)C(=O)CCC(=O)OC +CC(C)CCOC(C)C(=O)Nc1cnn(C(C)(C)C)c1 +COc1cc(C)ccc1OCC(=O)Nc1nc2n(c1C#N)CCS2 +Cc1ccc(NC(=O)C2CCCN2C(=O)c2ccccc2)cc1 +COc1ccc(C(C)COC(=O)C2CNC(=O)C2)cc1 +O=C(c1ccc(O)cc1)N1CCC(Cn2cc(C3CC3)nn2)CC1 +CCCn1nc(C(=O)N(C)Cc2nc3ccccc3[nH]2)ccc1=O +Cc1ncc(CNC(=O)N2CCC(OCC(C)C)CC2)s1 +O=C(O)C=C(c1ccc2c(c1)OCCCO2)C1CCCC1 +Cc1csc(NC(=O)c2csc(-c3cc4ccccc4[nH]3)n2)n1 +CC(O)CC1CCCN1C(=O)NCC(C)(C)c1ccncc1 +Cc1cn2nc(N3CCc4cnc(C(C)C)nc4C3)sc2n1 +Cc1ccc(OCC(=O)N(CC2CCCO2)c2ccncc2)c(C)c1 +CC1CN(C(=O)Cc2cccc(F)c2)C(C)CO1 +CC(C)(C)NC(=O)CNC(=O)N(Cc1ccco1)Cc1cccs1 +CCc1nn2c(=O)cc(CN3CCCC4(CNC(=O)O4)C3)nc2s1 +CC(NC(=O)CSc1nnc(NC2CC2)s1)c1ccccc1 +CC(NC(=O)c1cccs1)C(=O)OCCC(C)(C)C +Cc1[nH]c(=O)ccc1C(=O)N1CCCC1c1nc(-c2ccccc2)n[nH]1 +Cc1nnnn1-c1cccc(NC(=O)CCCC(=O)N(C)C)c1 +O=C1CN(C(=O)CSc2nc3cc(F)c(F)cc3[nH]2)CCN1 +COc1ccccc1-c1nnc(Sc2ccc(C#N)cn2)o1 +COC1CCC(CC(=O)Nc2ccc(-c3ccccc3)nn2)CC1 +Cc1ccccc1C(=O)N1CCCC(C(=O)Nc2ccccc2)C1 +O=C(Nc1nc(-c2ccsc2)ns1)c1csnn1 +Cn1cnn(CCOc2cc(Cl)ccc2Cl)c1=O +Cn1cccc1CN(C(=O)Cn1c(=O)oc2ccccc21)C1CC1 +CN(Cc1ccccc1F)C(=O)c1cccc(-c2nnnn2C)c1 +C=CCN1C(=O)NC2c3cccc(OCC)c3OC1(C)C2C(=O)OC +Cc1cc(Sc2ncccn2)ccc1NC(=O)c1ccncc1 +Cc1nnc2n1CCN(c1nc(-c3ccncc3)nc3ccccc13)C2 +CCCS(=O)(=O)NC1CCN(C(=O)Cc2ccc(C)nc2)CC1 +CCCCN1CNc2c(c(=O)[nH]c(=O)n2-c2cccc(Cl)c2)C1 +CC(Nc1cccc(NC(=O)CO)c1)C(=O)N(C(C)C)C(C)C +Cc1sc2ncn(CCC(=O)Nc3cnn(C)c3)c(=O)c2c1C +Cc1c(C(=O)NCC2(C)CCCO2)cnn1-c1ccncc1 +Cn1c(-c2ccncc2)nc2cc(S(=O)(=O)N3CCCC3)ccc21 +O=C(CNC(=O)c1c[nH]c2cccc(F)c12)NCCc1ccccc1 +Cc1ccsc1CNC(=O)Nc1ccccc1N(C)C +Cc1cccc(OCCn2c(C)ccc(C#N)c2=O)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)CC1CCCC1 +CN1CCOC(C(=O)Nc2ccc(-n3ncc4ccccc43)cc2)C1 +COc1ccc(C(C#N)NCc2cccc(C)c2)cc1 +CCc1nc(C(N)=O)c2[nH]c(=O)n(-c3ccc(OC)cc3)c2n1 +CCS(=O)(=O)Nc1ccc2c(c1)CCC(=O)N2CCC(C)C +Cc1cccc(N(CCC(N)=O)Cc2coc(-c3cccs3)n2)c1 +O=C(Cc1coc2cc3c(cc12)CCC3)NCc1cccs1 +COc1ccc(OCC(=O)Nc2cc(N)ccc2OC)cc1 +COc1cc(C)ccc1NC(C)C(=O)Nc1ccc(C(N)=O)cc1 +Cc1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1)CCC(=O)N2C +COC(=O)c1cc(CNc2cc(C(=O)NC3CC3)ccc2C)oc1C +COc1ccc(CCC(=O)N2CCc3ccccc32)cc1 +CCOc1cccc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1 +COc1cc(C(=O)NCc2ccccc2F)on1 +CC(C)NC(=O)COc1cccc2c1NC(C)CC2 +CCC(C)C(C)NC(=O)Nc1ccc(S(=O)(=O)CC)cc1 +Cn1c(C(=O)NCC(C)(C)C)nnc1-c1ccncc1 +N#Cc1cccc(C(=O)N2CCC(c3ccsc3)CC2)c1 +COc1cc(N=C(O)Cn2ccnc2)cc(OC)c1 +CCC(CC)C(=O)N1CCCC1C(=O)c1ccc(F)cc1 +COCC1CCCC12CN(C(=O)c1cnccn1)CCO2 +CCCNc1nc(-c2cc(C)nn(C)c2=O)cs1 +Nc1nc(N)nc(CSc2nnc(-c3ccncc3)n2C2CC2)n1 +Cc1ccc(N2CCCC2=O)c(C(=O)NCCc2nc(C)no2)c1 +COC(=O)c1ccc(C(=O)Nc2cccc(F)c2)cn1 +Cc1cc(C)n(-c2ccc(CNC(=O)NC3CCCCCC3)cn2)n1 +CC(C)(CNC(=O)CCN1CCOC1=O)c1ccc2c(c1)OCCO2 +CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2ccccc2C)cc1 +COc1ccc(-c2noc(Cc3nnc4nc(C)cc(C)n34)n2)cc1 +O=C(Nc1ccncc1)Nc1ccccc1COc1ccccc1 +CC(=O)c1c(C)[nH]c(C(=O)N2CCCSc3ccccc32)c1C +N#Cc1nc(N)n(Cc2cn3cc(Br)ccc3n2)c1C#N +O=C(c1cn2cccnc2n1)N1CC=C(c2c[nH]c3ccccc23)CC1 +O=C(OCCNc1cccnn1)c1cnc(C2CCCO2)s1 +COc1cccc(N2Cc3cc(Br)ccc3OCC2=O)c1 +O=C(NCC(F)(F)F)Nc1cnn(CC2CCCO2)c1 +COC(=O)c1cccc(OS(=O)(=O)c2cc(F)ccc2F)c1 +CCC(=O)Nc1ccc(OC)c(N2CCCC2=O)c1 +COc1ccc(-c2nnn(CC(=O)Nc3ccccc3Cl)n2)cc1 +Cc1nc(CSc2n[nH]c(C=Cc3ccc(F)cc3)n2)cs1 +CSc1nnc(NC(=O)CNC(=O)c2ccc(Cl)cc2)s1 +Cc1cccc(C)c1NC(=O)c1cc2c(nc1N)CCC2 +CSc1ccccc1NC(=O)c1cnc2ccc(C)cn12 +CC(C)c1nc(OCC#N)c(C#N)c2c1COC(C)(C)C2 +CC1CN(CCNC(=O)c2cc(-c3ccccc3)[nH]n2)CC(C)O1 +Cc1cnc(C(=O)Nc2ccc(Br)c(C)n2)cn1 +Cn1c(NC(=O)COc2ccc3ccccc3c2)cc(=O)n(C)c1=O +CCC(C)Nc1nc(-c2ccc(=O)n(CC)n2)cs1 +CC(c1ccc(F)cc1)N(C)C(=O)c1ccc(Cn2cccn2)cc1 +CCCn1nnc(NC(=O)c2cc(OC)cc(OC)c2)n1 +Cc1cccc(C(C)C)c1NC(=O)C(C)Oc1ccccc1C#N +Cc1ccccc1-c1nnn(CC(=O)N2CCCCC2C)n1 +Cc1cccc(-n2ccnc2SCC(=O)NC2CC2)c1C +Cc1nc(-c2cccc(OCC(=O)c3ccc(F)cc3)c2)no1 +O=C1CCN(C(=O)C2COc3ccccc3O2)CCN1 +CCc1noc(CC)c1CNC(=O)C(C)Oc1cccc(C#N)c1 +Cc1ccccc1C(=O)N(C)C(C#N)c1ccccc1Cl +Cc1cc(CNC(=O)C(C)Oc2ccccc2)c(C)o1 +Cc1ccc(-c2nnc(NC(=O)C3CCC(=O)N3)s2)c(C)c1 +CN(CCC(F)(F)F)C(=O)c1cccc(Cl)c1Cl +COC1CCCCC1NC(=O)Nc1cnccc1C +CC(C)c1nn(C)c(N2CCOCC2)c1CNc1ccc(F)cn1 +O=C(CC1OC(=O)c2ccccc21)NCc1cccc(OC(F)F)c1 +O=C1CCC(C(=O)Nc2cccc(C(=O)Nc3cccc(F)c3)c2)N1 +CCOC(=O)c1cc(C(=O)Nc2ccc3c(c2)OCCO3)nn1C +COCc1nnc(NC(=O)c2ccc3c(c2)OCO3)s1 +CCOc1ncccc1CNC(=O)Nc1ccccc1 +O=C(Nc1nc(-c2ccccn2)cs1)c1n[nH]c2ccccc12 +Cc1ccc(C)c(OCCC(=O)NCc2ccncc2)c1 +CC(=O)Nc1ccc(CNc2cc(Cl)ccc2C)cc1 +Cc1cnccc1CCNC(=O)Nc1ccc2c(c1)CCCO2 +COc1ccc(CC(=O)N2CCC3(CCNC3=O)CC2)cc1 +O=C(C1CC=CCC1)N(Cc1ccoc1)Cc1cccs1 +CC(C)c1cc(NC(=O)c2cccc(N3CCOC3=O)c2)[nH]n1 +CNS(=O)(=O)c1ccc(C(=O)NC2CC3CC2C2CCCC32)cc1 +O=C(Nc1scnc1-c1ccc(F)cc1)c1ccc2nncn2c1 +C=CCN(Cc1ccccn1)C(=O)c1cc(C)nc2c(C)cccc12 +Cn1cnc2cc(CCC(=O)Nc3nc[nH]n3)ccc21 +N#CCOC(=O)c1ccccc1SCC(=O)N1CCCC1 +NC(=O)c1nccc(S(N)(=O)=O)c1OC1CC1 +CC(=O)c1c(C)[nH]c(C(=O)N(C)c2ccccc2)c1C +Cc1noc(CCCC(=O)NC(C)(C)c2ccc3c(c2)OCO3)n1 +NS(=O)(=O)N1CCN(Cc2nnc(C3CC3)o2)CC1 +CN(Cc1ccccc1)c1ncccc1CNC(=O)c1cscn1 +Cc1nn(CCC(=O)NCc2cccnc2)c2ccccc12 +Cc1nccc(-c2cccc(NCc3nnc(C4CC4)o3)c2)n1 +Cn1cc(C(=O)N2CCC(Oc3cnccn3)CC2)cn1 +CCn1c(=NC(=O)COC)[nH]c2cc(Br)ccc21 +Oc1ccc(Cl)c2c1CCNC2C1CCOCC1 +O=C(c1ccccc1Br)N1CCOC(c2ccccc2)C1 +Cc1cc(C)n2ncc(-c3noc(CN(C)S(C)(=O)=O)n3)c2n1 +COC(=O)C(C)(C)NCc1c(OC)cccc1OC +O=C(CCc1ccncc1)Nc1cccc(Oc2cccnn2)c1 +CN(Cc1ccccc1F)S(=O)(=O)c1cccc(C(N)=O)c1 +Cc1ccc(C)n1-c1sccc1C(=O)NCC(=O)N1CCCC1 +CC(C)Oc1cccc(CNC(=O)c2csnn2)c1 +CC(NC(=O)C(C)(C)C)C(=O)Nc1cc(Cl)c(N)c(Cl)c1 +COCCCNc1ccc(CN2CCOCC2)cc1 +COCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)C(C)C +CCN1CCc2c(sc3c2c(NCCOC)nc2nnnn23)C1 +CCc1noc(CC)c1CNC(=O)C(C)Cc1cccs1 +CC(=O)N(C)c1ccccc1NC(=O)C(C)Cc1ccccc1F +CC(C)Cc1nc(COc2nnc(-c3ccccc3)o2)no1 +CCOC(=O)CNC(=O)CCn1cnc2ccccc2c1=O +Cc1ccccc1C(=O)Nc1sc2c(c1C(N)=O)CCCCC2 +CNC(=O)NC(C)(C)C(=O)N(C)Cc1csc(C)n1 +Cc1cc(C)n2c(CN3CCCC3COc3ccccc3)cnc2n1 +NC(=O)COC(=O)c1sccc1-c1ccc(F)cc1 +COc1ccccc1S(=O)(=O)NCC#CCOc1ccc(C)nc1 +Cc1nn(C)c(C)c1CCC(=O)Nc1ccccc1Cl +CCn1nnc2cc(C(=O)NCC(O)c3ccco3)ccc21 +COC(=O)c1noc(C(=O)n2cnc3ccccc32)c1N +COc1ccccc1C(=O)Nc1ccc(C)cc1N +COc1ccc(CC(=O)Nc2ccc3c(c2)CN(C(C)=O)CC3)cc1 +Cc1nn(C)c(=O)n1N(C)c1ncc(C(F)(F)F)cc1Cl +Cc1ccc(CC(=O)Nc2ccccc2C(F)(F)F)cn1 +C=CCOc1cccc(C(=O)NCc2cccnc2)c1 +COC(=O)C1CCCC1NC(=O)Nc1cccc(Br)c1 +COc1ccc(NC(=O)CCC(=O)c2cc(C)sc2C)cn1 +O=S(=O)(c1cccc(Cl)c1Cl)N1CCCCC1 +CCCc1nc(CNc2ncnc(C)c2C)cs1 +COc1ccccc1CC(C)NC(=O)c1cc(NC(C)=O)ccc1F +CCN(Cc1ccco1)C(=O)Nc1cccc(OC)c1 +CC(C)OC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 +COCC(O)CN(C)C(=O)Nc1cccc2ccccc12 +CCc1c(C(=O)N2CCCC2Cn2cccn2)cnn1-c1ccccc1 +CC(C(N)=O)N1CCOC(c2ccc(Cl)c(Cl)c2)C1 +Cn1c(=O)c2c(SC3CCCC3)nc(C(C)(C)C)nc2n(C)c1=O +COCCCC(=O)N(C)Cc1ccc(SC)cc1 +CCCn1nnnc1NC(=O)c1ccc(C)c(C)c1 +Cc1cc(=O)n2cnc(Nc3cccc(C(F)(F)F)c3)nc2n1 +Cc1cc(C)n2nc(C)c(C(=O)N(C)Cc3ccccc3C)c2n1 +COc1cccc2c1C(c1ccc(C)nc1)NCC2 +Cc1cccc(NC(=O)c2ccc(O)c(Cl)c2)n1 +Cc1ccc(C(=O)NCC(=O)N2CCCC(c3nccs3)C2)s1 +Cc1ccsc1C(=O)NCC(c1ccc(F)cc1)N1CCOCC1 +CCC(C)N(C)C(=O)c1cc(-c2ccccc2)nc2c1c(C)nn2C +O=C(Cn1cnc2ccc(Cl)cc2c1=O)N1CCOCC1 +O=C(NCc1cccc(O)c1)c1cc2cc(F)ccc2[nH]1 +Cc1ccc(OC2CCN(C(=O)C3CN(C)C(=O)N3)CC2)cc1 +COc1ccccc1CC1NCCc2c1ccc(F)c2O +Cc1cccc(C(N)C(=O)NCCCOC(C)C)c1 +Cc1ccc(C(C)OC(=O)CCc2cnn(C)c2)cc1 +Cc1cc(C(=O)NC2CCc3c(F)cccc32)n(C)n1 +OCc1ccc(C2NCCc3cc(Cl)ccc32)cc1 +Cc1ccc(C(=O)NC2CC(C)(C)Cc3oc(C)cc32)c(=O)[nH]1 +N#Cc1ccccc1Cn1c(-c2cccc(N)c2)csc1=O +CC(C)CNC(=O)C(C)N1C(=O)c2cccc3cccc1c23 +Cc1ccc(N2CC(C(=O)OCCCc3cccnc3)CC2=O)cc1 +CNC(=O)c1nc(C(=O)NC(C)c2ccc(OC)c(OC)c2)cs1 +Cc1cccc(Cl)c1S(=O)(=O)NC(C)(C)C +Cc1ccccc1CNC(=O)Nc1ccc(F)cc1F +CCN(CC)C(=O)c1cc(NC(=O)C(C)(C)C)c(=O)n(C)c1 +Cc1c(C(=O)N2CC3CCCC3C2)cnn1-c1ccncc1 +O=C(NCc1ccnc(N2CCOCC2)n1)Nc1ccc(F)cc1F +COC(=O)c1cc(Cl)cc(S(=O)(=O)N2CCOCC2)c1 +COCCn1c(=O)n(CC(=O)N2CC(C)CC(C)C2)c2cccnc21 +COC(C)C(=O)NCC12CC3CC(CC(Cl)(C3)C1)C2 +COc1c(O)ccc2c1C(c1ccncc1Cl)NCC2 +Cc1occc1C(=O)NC1CCc2[nH]c(=O)ccc2C1 +COc1ccccc1OCC(=O)Nc1nnc2n1CCS2 +NC(=O)CC1CCCN(C(=O)Nc2ccccc2-c2ccncc2)C1 +CS(=O)(=O)N1C2C=CC(C2)C1(C(F)(F)F)C(F)(F)Cl +Cn1ncc(C(=O)Nc2cccc(C(F)(F)F)c2)c1-n1cccc1 +Cc1c(C#N)nnn1C(C)C(=O)Nc1ccc(Cl)cc1 +CCOC(=O)C1CCCN(C(=O)Nc2ccc(F)c(F)c2F)C1 +COc1ccc(NS(=O)(=O)c2cc(N)ccc2Cl)cc1 +CC(C)(C#N)c1ccc(-c2cc(C3CC3)ncn2)cc1 +C#CCNC(=O)CCc1c(C)nn(CC(C)C)c1C +COCCCNC(=O)c1nc(C)n(-c2ccc(F)cc2)n1 +COc1ccc(CC(=O)Nc2nc(C)cs2)cc1F +CS(=O)(=O)Nc1cc(CC2CCCCC2)ccc1O +COc1ccc(C(O)CNc2ccccc2C)c(OC)c1 +O=C(Cn1cnccc1=O)Nc1cc(N2CCCCC2)ncn1 +O=C(NC1CCCC1)c1nc(-c2ccc(F)cc2)no1 +Cn1cc(C2CCN(C(=O)c3cccc(-c4ccoc4)c3)CC2)cn1 +Cc1cnc(C(=O)Nc2ccc3[nH]ccc3c2)cn1 +CCc1c(C(=O)NCCc2ccc(C)c(OC)c2)[nH]c(C)c1C(C)=O +Cc1cnc(C(C)(C)NC(=O)NCCc2ccc(F)cc2C)s1 +CC(=O)NCC(=O)NCC(=O)N1CCCC1c1ccc(C(C)C)cc1 +CCNC(=O)CNC(=O)Cc1csc(NC(=O)c2ccccc2)n1 +COC(=O)c1cccc2c1CCCN2CC(=O)Nc1nncs1 +Cc1ccc(OCC(=O)NCC(C2CCOC2)N2CCOCC2)cc1 +Cc1noc(CCCC(=O)N2CCN(C3CCCC3O)CC2)n1 +Cc1cc(NC(=O)NCC(C)(O)c2ccsc2)ccc1C(N)=O +CCC(=O)c1ccc(OCC(=O)N(C)CC(=O)N(C)C)cc1 +Cc1nc(NC(=O)c2cccc(Cl)c2)sc1C(=O)N(C)C +O=C(Nc1cccc2ncccc12)c1cncc(Br)c1 +CNC(=O)c1nc(C(=O)N2CCc3ccccc3C2)cs1 +CCCCn1nccc1NC(=O)C1CC(=O)N(CC)C1 +COC(=O)C1=C(CN2CCCC2)NC(=O)NC1c1ccc(C)cc1 +COc1ccc(C2CCCN2c2ncnc3c2cnn3C)cc1 +CN(CCc1ccncc1)C(=O)Nc1ccc(C(F)(F)F)cc1 +COc1ccc(S(=O)(=O)N(C)c2cccc3ncccc23)cc1 +COc1cccc(OCCN2C(=O)CCS2(=O)=O)c1 +CC(C)NC(=O)COC(=O)c1cnc(-c2ccccc2Cl)s1 +CN(C)C(=O)c1noc2c1CN(c1ncnc3cc(F)ccc13)CC2 +O=C(OCCc1cccnc1)C1CC(=O)N(c2ccc(Cl)cc2)C1 +CCOC(=O)C1CCN(C(=O)CN2CCN(CC(F)F)CC2)CC1 +CC(OC(=O)c1ccc(-n2ccnc2)cc1)C(C)(C)C#N +CC(C)CNS(=O)(=O)c1cnn(-c2ccccn2)c1 +CCCS(=O)(=O)Nc1ccc2c(c1)N(C(=O)C1CCCO1)CC2 +Cc1ccc(C)c(OCc2cc(C(=O)N(C)CC(O)CO)no2)c1 +COCCn1c(C2CCN(C(=O)C3CCCC3)C2)nc2cccnc21 +CCC1CCCN(c2cc3c(cc2N)CC(=O)N3)C1 +Cn1cc(S(=O)(=O)NC2c3ccccc3CC2O)cn1 +O=C(OCCNc1ncccn1)c1cccc(-n2cccc2)c1 +CC(CCN1CCOCC1)NC(=O)c1cc2ccccn2c1 +O=C1NC(c2cccnc2)Nc2sc3c(c21)CCCC3 +Cc1cc(C)c(NC(=O)CNC(=O)CSc2nccn2C)c(C)c1 +COc1coc(C(=O)Nc2nc3ccc(Cl)cc3s2)cc1=O +O=C(Nc1ccc(SC2CCCC2)cc1)c1ccc(=O)[nH]c1 +COc1ccc(C2CCN(C(=O)c3ccc(C)c(N)c3)C2)cc1 +Cc1ccc(C)c(N(C)Cc2cc(=O)n3nccc3[nH]2)c1 +CN1C(=O)CCc2cc(COC(=O)CNC3CC3)ccc21 +CNc1ccc(C(=O)Nc2ccc(Br)cc2)cn1 +Cn1nc(C(=O)NCC(C)(C)c2ccccc2Cl)ccc1=O +CC(C)n1nccc1NC(=O)c1cccc(NC(N)=O)c1 +Cc1noc(C2CN(C(=O)Cc3ccc(F)cc3)C2)n1 +CCC(=O)N1CCc2sc(C(=O)N3CCN(CC)CC3)cc2C1 +CCOC(=O)C1CCCN(C(=O)c2csc(-c3cnn(C)c3)n2)C1 +CC(NS(=O)(=O)N1CCOC1=O)c1ccccc1 +Cc1nc2nnc3ccc(C(=O)Nc4cccnc4)cc3c2n1C(C)C +CC(O)(CNC(=O)c1cccc(Oc2cnccn2)c1)c1ccccc1 +COCCN(C)c1ccc(C(=O)N2CCCC(COC)C2)cn1 +CCN(C1CCN(C(=O)Cc2cccc(C)c2)CC1)S(C)(=O)=O +CC(C)OCCCC(=O)Nc1cncc2ccccc12 +Cc1ccc2c(c1)C(=O)OC(C(=O)NC1CCCC1)C2 +c1sc(C2CC2)nc1CN1CCCC2(C1)OCCO2 +C#Cc1cccc(NC(=O)C(NC(=O)c2cccs2)C(C)C)c1 +CC1NCCc2cc(Cl)cc(Br)c21 +Nc1cc(Br)ccc1Br +Cc1ccc2nc(SCc3n[nH]c(=O)[nH]3)[nH]c2c1 +CCOC(=O)c1nc(C)c(-c2c[nH]c3ccccc23)nc1NC(C)=O +C#CCNS(=O)(=O)c1cccc(C(=O)NC(C)C(C)CC)c1 +Cc1cc(N)nc(SCCN2CCOC2=O)n1 +O=C(NCCOc1ccc(F)cc1)NCCc1cccs1 +c1ccc(CCc2nc3nccc(-c4ccco4)n3n2)cc1 +COc1ccc(CNC(=O)c2csc3ccccc23)cc1 +Cc1nnc(NC(=O)Cc2coc3ccc4ccccc4c23)s1 +O=C1CCCc2cc(OC(=O)c3cccnc3OCC(F)F)ccc21 +COc1ccc2c(CCNc3nc(=O)c(C)n[nH]3)c[nH]c2c1 +CC(NC(=O)c1cccs1)C(=O)Nc1ccc(C(N)=O)cc1 +O=C(Nc1nc2ccccc2s1)c1ccc(-n2ccnn2)cc1 +Cc1c(NS(C)(=O)=O)cccc1C(=O)N(C)c1ccccc1 +Cn1cnc(CNC(=O)N(Cc2ccco2)CC2CCCO2)n1 +CCn1c(SCC(=O)NCc2cccs2)nnc1C1CC1 +c1ccc2c(c1)CCN(c1nc3cc4c(cc3s1)OCCO4)C2 +Cc1noc(CNC(=O)C2CCN(C(=O)c3cccs3)CC2)n1 +CCNC(=O)c1ccc(C)c(NC(=O)c2ccc(F)c(COC)c2)c1 +COC(=O)CC(C)C(=O)c1ccc2c(c1)CCCC2 +COC(=O)c1ccccc1C(=O)NCC#CCOc1ccc(C)nc1 +Cc1cccc(N)c1S(=O)(=O)NC(C)C(N)=O +CCN(CC)C(=O)c1cnc(-c2ccco2)nc1N +CCOC(=O)C(N)c1cccc(NC(=O)OC(C)(C)C)n1 +COc1ccc(OC)c(S(=O)(=O)NCCC#N)c1 +CCn1c(=O)c(C(=O)NCc2ccccc2)nc2cccnc21 +CCC(C)NC(=O)Nc1cccc(-c2nnnn2CC)c1 +CC(NC(=O)c1cccc(NC(N)=O)c1)c1cccc2ccccc12 +CCOCCCNC(=O)N1CCN(c2nccs2)CC1 +CC(OC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C)c1ccccc1 +O=C(c1ccc(F)cc1Br)N(CCO)CC(F)(F)F +O=C1CSc2nc(-c3c(F)cccc3Cl)nn21 +CCc1nnc(CN(C)c2ncnc3[nH]ccc23)o1 +COc1cccc2sc(NC(=O)CC(C)C)nc12 +CC(=O)N(Cc1nccn1Cc1ccc(F)cc1)CC(C)C +Oc1cc(O)cc(C2NCCc3c(F)cc(F)c(F)c32)c1 +Cc1ccc(C(=O)NCCc2ccccc2)cc1N1CCCC1=O +O=C(CN1C(=O)COc2ccccc21)Nc1ccc2[nH]ccc2c1 +COCc1nc(C(=O)N2CCN(C)CC2c2ccccc2)cs1 +COc1ccccc1NC(=O)N1CCCC1c1cc(C)no1 +CC(=O)NCc1ccc(-c2nc3ccccc3s2)cc1 +COc1ccc(C2=CC(c3ccc4c(c3)OCO4)=NC(=O)C2C#N)cc1 +Nc1c[nH]c(=O)c(C(=O)Nc2ccc3c(c2)OCCO3)c1 +COc1cc(C#N)ccc1OCC(=O)NC1(C)Cc2ccccc2C1 +CC(=O)c1ccc(S(=O)(=O)Cc2cccc(N(C)C)c2)cc1 +CCc1nnc2c3c4c(sc3ncn12)CCCC4 +CNC(=O)c1cnc(COc2ccc(Cl)c(C)c2)nc1N +COC(=O)c1ccccc1NC(=O)COC(=O)c1ccc(F)cc1 +CCN(CCC#N)C(=O)Nc1cc(F)ccc1OC +CCn1cc(C(=O)NCCOc2ccc(Br)cc2)cn1 +COCC(=O)N1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1 +CC(=O)Nc1cc(S(=O)(=O)Nc2c(C)c(C)nn2C)ccc1C +CN(Cc1ccc(OC(F)(F)F)cc1)C(=O)c1ccc2[nH]cnc2c1 +CCc1nc2cc(-c3noc(-c4ccncc4)n3)ccc2o1 +CC1COc2ccc(Br)cc2N(C)C1=O +CC(C)(C)c1cnc(CN2CCC(=O)Nc3cc(F)ccc32)o1 +O=C1c2c(O)ccc(Br)c2CN1CCO +CC1Oc2ccc(NC(=O)c3ccc(-n4cccn4)cc3)cc2NC1=O +CCC(NC(=O)CNS(C)(=O)=O)c1ccc(Br)cc1 +Cc1ccc(NC(=O)CNc2ccc(C(=O)N(C)C)cc2)cc1C +Cn1ccc(-c2cc(C(=O)NCCn3ccnc3)c3ccccc3n2)n1 +N#Cc1ccc(C(O)C(O)c2ccc(C#N)cc2)cc1 +Cc1ccc(-c2noc(NCC3CCC(C(=O)N(C)C)O3)n2)cc1 +CC(c1nc2ccccc2s1)N(C)C(=O)Cn1ccc(=O)[nH]c1=O +CCC1CCCCN1C(=O)C(C)Sc1ccc(NC(C)=O)cc1 +Cn1nc(CNC(=O)NC2CCCC2)c2ccccc2c1=O +COc1ccnc(NC(=O)CCCc2nc(C3CC3)no2)c1 +O=C(NCC(O)c1ccccc1)c1cnn(-c2cccc(Cl)c2)c1 +Cc1ccnc(C(NC(=O)CCc2n[nH]c(C)c2C)C2CC2)c1 +CCc1onc(C)c1NC(=O)N(C)Cc1nc(C(F)(F)F)cs1 +Cc1nccn1-c1ccc(CNC(=O)CNC(N)=O)cc1F +O=C(NCC(O)C1CCCCC1)c1ccc2c(c1)OCO2 +COC(=O)c1cccc(OCC(=O)N(C)Cc2ccc(F)cc2)c1 +COc1ccc(S(=O)(=O)Oc2ccc(C#N)c(F)c2)cc1 +CCc1nnc(NC(=O)Cc2c(CC)noc2CC)s1 +CCC1=C(C(=O)OC)C(c2sccc2C)NC(=O)N1 +CS(=O)(=O)N1CCC(Oc2nc3c(F)cccc3s2)CC1 +COc1ccc2c(c1)CN(S(=O)(=O)c1ccc(C)cc1)CC2 +CN(C)C(=O)CNC(=O)c1sccc1-c1ccccc1 +Cc1ccc(OCCNc2cccc(C(=O)N3CCOCC3)c2)cc1 +Nc1c(-c2ccc(Cl)cc2)nnn1-c1ccccc1 +Cc1ccc(C(=O)NC2CCCC2C(N)=O)cc1N1CCNC1=O +Cc1cc(NC(=O)c2scnc2C2CC2)c[nH]c1=O +CC(=O)N1CCc2ccc(NC(=O)COc3ccccc3)cc2C1 +COc1ccccc1CNC(=O)c1cc(Cl)ccc1N +CCOc1cccc(NC(=O)N2CCOC(C)(C)C2)c1 +CNC(=O)c1cccc(NC(=O)C2(C)CC2(Cl)Cl)c1C +COc1cc(O)c(Br)c(OC)c1Cl +CC(Cc1ccccc1F)C(=O)NCCNC(=O)C(C)(C)C +CC(=O)N1CCc2cc(NC(C)C(=O)Nc3ccccc3)ccc21 +CCCN(C)C(=O)c1cc(C2CC2)nn1-c1ccccc1 +CC(C)c1nnc(SCC(=O)NCc2ccco2)n1C +CCC(C)NC(=O)C(C)S(=O)(=O)c1nc(C)cs1 +O=C1CSc2ccc(C(=O)OCCOc3ccccc3)cc2N1 +COc1cc(C)c(-c2cc(=O)[nH]c(N)n2)cc1C(C)(C)C +Cc1cccnc1NC(=O)CCS(=O)(=O)c1ccc(Cl)cc1 +CC(C)(C)NC(=O)C1CCCCN1C(=O)c1cc(C(N)=O)cs1 +COc1cccnc1C(=O)NCc1nc2cc(C)c(C)cc2[nH]1 +Cc1ccnc(-n2c(SCC(N)=O)nc3ccccc3c2=O)c1 +CC(Nc1ccc2nnnn2n1)c1ccccc1Br +NS(=O)(=O)c1ccc(NC(=O)CSc2ccc(F)cc2)cc1 +COc1ccc(OC)c(NC(=O)CCc2cccc(N)c2)c1 +Cc1nn(-c2ccccc2)c(C)c1N1CCN(Cc2ccccn2)CC1 +Cc1nc(C(C)(C)NC(=O)C(C)OCC2CCCO2)sc1C +CC1CCCC(NC(=O)CCc2nc(-c3cccnc3)no2)C1C +CCn1nc(NC(=O)NCc2cccc(N(C)C)c2)cc1C1CC1 +CCOc1ccc(F)c(C(=O)NCCCc2cnn(C)c2)c1F +O=C(NCCNc1ncccn1)NCC(O)c1ccc(F)cc1 +COC(=O)C(C)N(C(=O)c1ccc2ccccc2c1)C1CC1 +CCOC(=O)N1CCN(C(=O)CCn2ccc3ccccc32)CC1 +Cc1ccc(C)c(OCc2nc(C)c(CC#N)s2)c1 +CC(C)c1nc(CC(=O)NC2CCc3nnc(C(C)C)n3C2)cs1 +Cc1cc(OCC(=O)NCc2ccccc2)nnc1C +CC(C)CCCC1CN(C(=O)c2cn[nH]c2)CCO1 +Cc1ccnc(C(NC(=O)c2ccc(-c3cc[nH]n3)cc2)C2CC2)c1 +CC1CN(C(=O)CCC(=O)c2ccc3ccccc3c2)CC(C)O1 +COC(=O)c1cc(S(=O)(=O)N2CC(C)CC(C)C2)cn1C +Cc1nc(-c2cnccn2)sc1C(=O)NCc1ccncc1 +Cc1ccc(NC(=O)NC(C)c2ccncc2)c(Br)c1 +O=S1(=O)N=C(Nc2cccc(F)c2)c2ccccc21 +COc1ccc2occ(CC(=O)Nc3ccccc3F)c2c1 +COc1cc(NC(=O)c2cc3c([nH]c2=O)CCCC3)cc(OC)c1 +CCc1nc(CC(=O)Nc2nnc(C)s2)cs1 +COC(=O)c1cc(CNC(=O)c2cccnc2)ccc1OC +O=C(NCC1CC1)c1cc(C2CC2)nc2onc(-c3ccco3)c12 +O=C(NCCc1ccc(F)cc1)C1CN(Cc2ccccc2)CCO1 +CCC(CC)C(=O)Nc1cccc(S(=O)(=O)N(C)C)c1 +Cc1ccc(N2CC(C(=O)N(C)C3CCC3)CCC2=O)cc1C +C=CCN1CC2(CCC1=O)CCN(C(=O)C1CNC(=O)N1)CC2 +COc1ccc(F)cc1CCN(C)C(=O)CC#N +Cc1cc(=O)[nH]c(SCC(=O)OCc2ccccc2)n1 +Cn1cnnc1SCCNC(=O)C1COc2ccccc2C1 +Cc1nc(C)c(-c2ccn(CC(=O)Nc3ccnn3C)n2)s1 +CCNC(=O)N1CCC(Oc2ccc(C#N)cc2)CC1 +COc1ccc(NC(=O)N(C)Cc2cc(C)on2)cc1OC +N#CC1CN(Cc2ccc(-c3cccc(Br)c3)o2)CCO1 +O=C(COc1ccc(NC(=O)C2CC2)cc1)NCc1ccc(F)cc1 +CN(CCc1cccc(Cl)c1)C(=O)c1cccc(N)c1 +COc1cc(NC(=O)NCC2Cc3ccccc32)ncn1 +Cc1cccc(OCC(C)NC(=O)c2ccc3c(c2)NC(=O)CO3)c1 +Cc1cccc(C(=O)Nc2ccc(Br)c(C)c2)n1 +N#Cc1ccc(-n2cnc3cc4c(cc32)OCCO4)nc1 +COc1ccc2nc(C(=O)NCCC(C)C)cn2n1 +CN(Cc1ccccn1)C(=O)c1cccc2ncccc12 +COC(=O)c1ccc(CSc2nc(C)c(CCO)c(=O)[nH]2)cc1 +CCC(C)C(NC(=O)c1ccn(-c2cccc(Cl)c2)n1)C(N)=O +CN(C)C(=O)CCNC(=O)c1ccc(OCC2CCCCC2)cc1 +Cc1ccc(S(=O)(=O)N2CCc3sccc3C2)cc1C +O=C(C1CCC1)N1CCC(n2nnc3c(O)nc(C4CC4)nc32)CC1 +CCOC(=O)C1CCCN1S(=O)(=O)NCc1cn[nH]c1 +COc1cc(Cl)c(-c2cc(N)nn2C)cc1Cl +COc1cc(C(=O)Nc2cc(C3CC3)n[nH]2)cc(OC)c1C +CCc1cccc(C)c1NC(=O)NCc1ccnn1C +O=C(NC1CCCCC1)N1CC(c2nc(-c3ccco3)no2)C1 +CCOC(=O)Cn1nc(C)c2c1N=C(O)CC2c1cccc(Cl)c1 +Cc1cc(NC(=O)Cn2ncc3cccnc32)n(-c2ccccn2)n1 +Cc1ccc2nc(SCc3ccc(C(=O)N(C)C)cc3)[nH]c2c1 +COc1cccc(CNC(=O)CNC(=O)c2cc(C)cc(C)c2)c1 +Cc1ccc(-n2nnc(-c3ccc(F)c(F)c3)c2N)c(O)c1 +CSc1nc(N(C)C)c2ccc(C(=O)N(C)C)cc2n1 +FC(F)(F)c1cccnc1CNc1cnn(CC2CCCO2)c1 +Cc1cc(NC(=O)c2ccc(F)cc2F)sn1 +CN(C)C(=O)CN(CC(F)(F)F)C(=O)CCc1ccccc1 +O=C(NCC(=O)N1CCCC2COCCC21)c1cc2ccccc2[nH]1 +Cc1cccc(Nc2nc(C(=O)Nc3ccccc3)cs2)n1 +O=C(Nc1ccccc1F)c1cc(=O)c2ccccc2o1 +NC(=O)C(NCC(F)(F)F)c1ccc(Cl)cc1Cl +COCCNC(=O)CCC(O)c1ccc(F)c(C)c1 +CC(c1ccco1)N(C(=O)Nc1cnn(-c2ncccn2)c1)C1CC1 +COC(=O)c1sccc1Cn1ccc(C)c(C#N)c1=O +COc1ccc(C2CCCN2Cc2nc3ccccc3c(=O)[nH]2)cc1 +COc1ccccc1C=Cc1ccc(C(N)=O)cc1 +OCc1nc2cccnc2n1Cc1ccc(Cl)c(Cl)c1 +CCCNC(=O)c1cc(Br)ccc1N +CNC(=O)c1cc(OC)ccc1NC(=O)C1CC1c1ccccc1 +Cc1nc2ccccc2c(=O)n1CCC(=O)Nc1cnn(C)c1 +COc1ccc(Cn2ncc(C)c2NC(=O)C2CC=CC2)cc1OC +CC(C)Cn1ncc(C(=O)N(Cc2ccccc2)C2CC2)c1C1CC1 +CCc1ccc(S(=O)(=O)NCC(OC)c2ccsc2)s1 +O=C1NCCCCC1Sc1nnc2n1CCCCC2 +COC(C)(C)c1noc(C=Cc2ccc(C3CC3C)o2)n1 +CCOc1cc(-c2nc(C3CC3)c(CO)s2)ccc1OC +Cc1ccccc1C(CC(C)C)NC(=O)Cc1ccc[nH]1 +CCCOc1ccccc1NC(=O)c1cc(Cl)c[nH]1 +C=CCN(CC=C)C(=O)CNc1ccc(F)c(F)c1F +O=C(CSc1nn2cnnc2s1)N1CCc2ccccc21 +COc1ccc(C(=O)NCC(C)(C)Cc2ccccc2)nn1 +CC(Oc1ccc(F)c(F)c1)C(=O)N1CCNC(=O)C1 +Cc1ccc(-c2cc(C(=O)NCc3ccc(F)cc3)ccn2)s1 +COc1ccc(S(=O)(=O)N2CCCC2c2cccs2)cc1 +c1ccc(Cc2nc3ccc4nonc4c3[nH]2)cc1 +CC(Sc1ccccc1Br)C(=O)N(C)C +CCOC(=O)N1CCN(Cc2nnc(-c3cccs3)o2)CC1 +O=C(NCCOc1ccc(F)c(F)c1)Nc1ccc2c(c1)COC2 +C(=C1CCN(c2cc(-n3ccnc3)ncn2)CC1)c1ccccc1 +Fc1cnc(N2CCCCC2)nc1N1CCOCC1 +CC1(C(=O)NCCCn2cccn2)Sc2ccccc2NC1=O +CC(C)Cc1nc(CNC(=O)c2cccc(F)c2)no1 +COc1ccc(NC(=O)NCCc2cn3ccccc3n2)cc1C +COc1cc(OC)cc(C(=O)N(CCC(C)C)C2CC2)c1 +Cc1ccnc(C(NC(=O)c2cscc2C)C2CC2)n1 +N#Cc1cnn(-c2cccc(F)c2)c1C(F)(F)F +COC(=O)C(NCc1cccs1)c1ccccc1F +CCS(=O)(=O)N1CC2CC(C(=O)NCC(C)C)C(C1)O2 +CNC(=O)CSc1nnc(-c2ccc(OC(F)F)cc2)o1 +CCN(CC(=O)Nc1ccc(OC)cc1)c1ncnc2c1cnn2C +COc1ccccc1OCCNS(=O)(=O)C(C)C +CCCCS(=O)(=O)Nc1ccccc1C(C)O +Cn1nc(C2CCC2)cc1NC(=O)N1CCC2(CCOC2)C1 +Cc1cc(CNC(=O)CSc2ccccc2C)c(C)o1 +Cc1cccc(C2(Cc3ccc(C)s3)NC(N)=NC2=O)c1 +CNC(=O)Cc1ccc(NS(=O)(=O)c2cccs2)cc1 +CCn1nnc(CO)c1-c1ccc(Br)cc1 +Cc1cccc(C(=O)Nc2cccc(OCc3ccc(F)cc3)c2)n1 +Cc1noc(C)c1CC(=O)NC(C)c1ccc2c(c1)CCCC2 +NC(=O)c1ccc(C(=O)N2CC=C(c3ccccc3Cl)CC2)nc1 +Cc1cnc(N2CCCC3(CCCN3S(C)(=O)=O)C2)nc1 +Cc1ccc(CNC(=O)N2CCc3sccc3C2)s1 +O=C(NCC(=O)N1CCCCCC1)c1cccc(OC(F)F)c1 +COc1cc(Nc2ccc(N)cc2C)cc(OC)c1 +Cc1cc(CC2COCC2NC(=O)CSc2ccccc2)on1 +Cc1ccc(CNC(=O)c2cc(S(N)(=O)=O)ccc2F)cc1F +CC(C)NC(=O)c1ccc(NC(=O)NCCO)cc1 +CCNC(=O)c1ccc(NC(=O)COc2cc(C)ccc2C)cc1 +CCOc1cc(-c2nc(-c3cccs3)n[nH]2)ccc1OC +O=C(c1csc(-c2ncccn2)n1)N(CC1CCCCC1)C1CC1 +Cc1cc2c(SC(C)C(=O)NCc3cccs3)ncnc2s1 +CC(C#N)NC(=O)c1ccc(-c2ccccc2)cc1 +CCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1Cl +Cc1c(C(=O)Nc2cc(F)ccc2Cl)cnn1-c1ccccc1 +Cc1cc(NC(=O)c2cc(C(C)(C)C)nn2C)n(C)n1 +N#Cc1ccc(NC(=O)N2CCN(c3nccs3)CC2)cc1 +CCc1nc2n(n1)CCCC2NS(=O)(=O)c1ccc(C(C)=O)cc1 +COc1cc(C=c2sc3nc4c(C)cccc4n3c2=O)ccc1O +Cn1ccnc1SCC(=O)Nc1ncc(Cl)cc1Cl +N#Cc1c(F)cccc1NCC(O)COc1ccc(F)cc1 +C=CCN1CCC2(CCCN(c3ccc(C)nn3)C2)C1=O +NC(=O)c1ccc(NC(=O)CC2CCCCC2)cc1Cl +COCCN(CC(C)C)C(=O)Nc1cccc(C#N)c1 +O=C(NCC(F)(F)F)c1cc(-c2ccco2)nc2ccccc12 +Cc1cc(=O)n2nc(CN(C)CCOc3ccccc3F)sc2n1 +CC(C)(C)c1cc(CNc2nncc(-c3cccc(F)c3)n2)n[nH]1 +CCCN(CCC)C(=O)C1CC(=O)N(c2ccc(OC)cc2)C1 +C#CCNC(=O)NCC(C)(C)c1ccccc1Cl +CC(=O)Nc1cccc(C(C)OC(=O)CC2CCCC2)c1 +COc1cc(CNC(=O)NCCC2=CCCCC2)ccn1 +c1ccc(-c2nnc(CN3CCCc4ccccc43)o2)cc1 +CCCCNC(=O)NCc1ccnc(-n2ccnc2)c1 +Cc1c(N)cc(C(=O)N2CCC(C)(C)CC2)cc1F +CCc1cccc(C)c1NC(=O)COc1ncnc2ccccc12 +CCCN1C(=O)C(O)(CC(=O)c2ccc(C)cc2)c2ccccc21 +CSc1nccn1-c1ccc(C(=O)Nc2cnn(C)c2)cc1 +Cc1nn(C)c(=NS(=O)(=O)c2cccnc2)[nH]1 +CC(C)(NC(=O)Cc1c(F)cccc1F)c1ccc2c(c1)OCCO2 +CCCNC(=O)NCCOc1cc(C)cc(C)c1 +O=C(NCC1CCCO1)c1cc2ccccc2[nH]c1=O +Cc1cc(F)ccc1NC(=O)NCCc1nc(C(C)C)no1 +CN1CCOC(CCNC(=O)c2ccc(-c3nnn(C)n3)cc2)C1 +Cc1nc2c(c(=O)[nH]1)CCN(C(=O)c1cnn(Cc3ccccc3)c1)C2 +Cc1ccc(C(=O)CSc2nnc(-c3ccncc3)o2)cc1 +Cc1cc(=O)c2cccc(C(=O)NC(C)C(N)=O)c2[nH]1 +COCCC(=O)Nc1ccc(C)c(S(N)(=O)=O)c1 +CC1CN(C(=O)C(C)n2cccn2)c2ccccc2S1 +Cc1cc(NC(=O)c2cccc(NC(=O)C3CCCO3)c2)n(C)n1 +Cc1nnc(NC(=O)CN2CCN(c3ccccc3)CC2)s1 +N#Cc1cc(F)ccc1NC(=O)NCC(=O)N1CCCCC1 +CC1CCCCN1S(=O)(=O)NCc1cccc(O)c1 +O=C(NCc1ccon1)C12CC3CC(C1)CC(n1cncn1)(C3)C2 +N#Cc1cc(Br)ccc1NCC1(CCO)CCOC1 +Cc1cc(NCCCN2CCOCC2)cc(=O)[nH]1 +Cc1nc2ccccc2c(=O)n1CCC(=O)N1CCCC1 +CCOc1cc(F)ccc1NS(=O)(=O)c1ccccc1F +CCC(CC(=O)OC)c1cc(Cl)ccc1OC +Nc1c(NCc2ccnc(OCC3CC3)c2)ncnc1-n1cccn1 +Cc1nc2c(c(C(F)(F)F)n1)CC(C(=O)N1CCCCC1)CC2 +CCOc1ncccc1C(=O)Nc1nc2ccc(OC)cc2s1 +CN(CCc1noc(-c2ccc(F)cc2)n1)C(=O)c1ccco1 +CCC(C)NC(=O)C(NC(=O)c1ccc(Cl)cc1)C(C)C +CC(=O)Nc1nc(CSc2nc3ccccc3c(=O)n2C)cs1 +Cc1nn(-c2ccccc2)c2oc(N)c(-c3nccs3)c12 +COc1ccc(-c2n[nH]cc2CNc2ncnc3c2c(C)nn3C)cc1 +O=S(=O)(c1ccccc1Cl)N(Cc1ccsc1)C1CC1 +CNS(=O)(=O)Cc1ccc2[nH]cc(Sc3ccccc3)c2c1 +COC(=O)c1cnn2c1nnc1c(=O)n(-c3cccc(O)c3)ccc12 +CCC(NC(=O)c1ncn(-c2ccccc2)n1)C(=O)N1CCOCC1 +NC(=O)C1CCCN(C(=O)CSc2ccccn2)C1 +Cn1nc(CC(=O)Nc2cc(F)c(F)c(F)c2)c2ccccc2c1=O +CCOCCCNc1nnnc2c1cnn2-c1ccccc1 +O=C(NCc1ccco1)c1ccc2c(c1)nc1n2CCCC1 +CCNC(=O)C1CCCN1C(=O)Nc1ccc2oc(C)cc2c1 +COC(=O)Nc1ccccc1C(=O)N1Cc2ccccc2C1 +CC1=Nc2nc(CCCO)nn2C(c2ccc(C)o2)C1C(N)=O +CCC(C)NC(=O)CCNS(=O)(=O)c1ccc2c(c1)CCCC2 +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccc2c(c1)NC(=O)CO2 +CC(CNC(=O)CCc1ccccn1)Oc1ccc(F)cc1 +C=CCc1cc(C(=O)Nc2cccc(C(C)=O)c2)cc(OC)c1OC +C=CCN1C(=O)C(Cc2ccccc2C)Oc2cc(N)ccc21 +CCC(C)C(NC(=O)c1ccn(-c2ccc(Cl)cc2)n1)C(N)=O +Cc1ccc(C)c(S(=O)(=O)Nc2ccc(-n3cnnn3)cc2)c1 +CCN1CCOC(CNc2ccc3nnc(-c4ccccc4)n3n2)C1 +Nc1cc(C(F)(F)F)ccc1SCC1CCOC1 +Cc1cccc(OCCNc2c(N)c(C)nn2C)c1 +Cn1cnc2cc(OS(=O)(=O)c3cccc(F)c3)ccc21 +O=C(CSc1c[nH]c2ccccc12)Nc1ccccc1 +CNS(=O)(=O)c1ccc(NC(=O)c2ccc(C)c(C)c2)cc1 +N#CCCN(CCC#N)C(=O)c1ccc2cc[nH]c2c1 +Cc1ccc(NC(=O)CCSc2nnnn2C)cc1 +CCn1nc(C)c(CNC(=O)NC(C)(C)c2ccccc2OC)c1C +CC(CNC(=O)Cn1cnc2ccccc21)c1ccccc1 +Cc1cc(C2CN(C(=O)c3ccn4ccnc4c3)CCO2)ccc1F +COc1ccccc1CNC(=O)CCCn1cccc1 +Cc1ccc(C)c(SC(C)C(=O)Nc2ccc(C(N)=O)cc2)c1 +O=C(Nc1cnn(CC2CC2)c1)c1ccc(F)cc1 +Cn1cnc(S(=O)(=O)N2CCC3(CCCO3)CC2)c1 +Fc1cc2c(c(F)c1F)C(c1ccoc1)NCC2 +CCN(C(=O)c1cc(OC)ccn1)c1ccccc1C +COc1ccc2c(c1)CN(S(=O)(=O)N1CCCC(C)C1)CC2 +Cc1ccc(OCC(=O)Nc2ccc3nc(C)oc3c2)cc1 +Cc1cc(C(=O)Nc2nccn(C)c2=O)ccc1NC(=O)CC(C)C +CCCN(CCC)S(=O)(=O)c1cc(-c2nnc(C)o2)co1 +CCOc1ccc(C(=O)Nc2cc3c(cc2Cl)OCO3)cc1OC +Cc1noc(COC(=O)C2CCN(C(=O)Nc3ccccc3)CC2)n1 +N#Cc1ccc(CNCC(c2ccc(F)cc2)N2CCOCC2)cc1 +COc1ccc(CCCC(=O)N2CCC(O)CC2)cc1 +Cc1ncsc1CNC(=O)c1ccnc(OC2CCC2)c1 +N#Cc1cccc(S(=O)(=O)Nc2cnn(Cc3ccccc3)c2)c1 +CC(C)(C)NC(=O)Nc1ccc(-c2nccs2)cc1 +CC(NC(=O)CCc1ccc2c(c1)OCO2)c1ccncc1 +O=C(OCCNc1cccnn1)c1cc(N2CCCC2=O)ccc1F +CN(CC(=O)Nc1ccc2c(c1)COC2)c1ncnc2[nH]cnc12 +Cc1occc1CN(C)C(=O)NCC1CCN(c2ccc(F)cc2)C1 +CCOC(=O)C(C)NC(=O)c1cnc2c(c1)c(C)nn2C +CN1CC(c2nc3ccccc3n2CC2CC2(Cl)Cl)CC1=O +COCCOc1cccc(C(=O)Nc2ccnc(C)c2)c1 +COc1ccc(S(=O)(=O)N(CC2CCOC2)C2CC2)cc1F +CC(=O)Nc1ncc(S(=O)(=O)NCc2ccccc2)s1 +CN(C)c1ccc(C(F)(F)F)cc1NC(=O)NCCO +O=C(Nc1ccnc2cc(C(F)(F)F)ccc12)c1ccccn1 +CCC1C(=O)Nc2c(C(O)CC(C)C)cc(Cl)cc21 +O=C(c1ccccc1Cl)N1CC(c2nc(-c3ccccn3)no2)C1 +Cn1ncc(N2CC=C(c3ccccc3)CC2)c(Br)c1=O +Cc1cccc(S(=O)CC(=O)NCCc2c(F)cccc2F)c1 +CC(C)OC(=O)c1nnn(-c2ccc(F)c(Cl)c2)c1N +Cc1nn2c(C)c(C(=O)N3CCCCC3)cnc2c1-c1ccccc1 +O=C1CNCC(C(=O)NCc2scnc2-c2ccccc2)N1 +CNC(=O)c1cnc(COc2ccc(Cl)cc2)nc1N +CC(C)CCCC(C)NC(=O)NCc1ccco1 +CCOC(=O)CCN1C(=O)COc2ccc(C(C)=O)cc21 +CCCNC(=O)Nc1ccc(F)c(NC(=O)Cc2ccccc2)c1 +Cc1nc(-c2ccsc2)ccc1C(=O)N1CCN(CC(N)=O)CC1 +N#Cc1ccc(N2CCN(c3ccc(O)cc3)CC2)nc1 +CC(C)CNC(=O)CNc1cccc(OC(F)(F)F)c1 +O=C(COc1ccc2c(c1)C(=O)CC2)NCc1cccs1 +N#Cc1ncn(CC(=O)NCCc2c(F)cccc2F)n1 +CC(C)COC(=O)c1cccc(OCC(N)=O)c1 +CNC(=O)c1cc(S(=O)(=O)Nc2ccc(C(C)=O)cc2)cs1 +CC(C)Sc1ccc(C(O)Cn2cc(N)cn2)cc1 +NS(=O)(=O)c1ccc(F)c(C(=O)NCc2ccc(Cl)cc2)c1 +CNC(=O)c1ccc(NC(=O)Cn2cnnn2)cc1 +Cc1ccc2c(c1)nc(C(=O)Nc1ccc(F)cc1)n2C +N#Cc1cccc(OCCn2nc(-c3ccco3)oc2=O)c1 +COC(=O)c1ccc(N2CCN(c3nnc(C)s3)C(C)C2)cc1 +Cc1ccc(C(N)=O)cc1NC(=O)c1cncc(Br)c1 +COc1c(C)cnc(CNC(=O)c2sccc2C#N)c1C +CNC(=O)C1CCCN(C(=O)NC(C)c2ccc(F)cc2Cl)C1 +Cc1cc(C)nc(C(C#N)C(=O)CCc2ccc(Cl)cc2)n1 +Cc1c(C)n(Cc2ccncc2)c2ncnc(NCCO)c12 +O=C(OCC1CCCCO1)c1cc(-c2ccccc2)[nH]n1 +COCc1nnc2sc(-c3ccc(Cl)c(Cl)c3)nn12 +COc1ccc(OC)c(C(=O)Nn2cnc3ccccc3c2=O)c1 +Cn1c(=O)n(C)c2cc(C(O)c3cc4ccccc4o3)ccc21 +CC(=O)Nc1ccccc1CNc1cnn(CC(F)F)c1 +O=C(NCc1ccc2[nH]c(=O)[nH]c2c1)C1CCOCC1 +COc1ccc(-c2nnc(C3CCN(C(=O)c4ccccc4)C3)o2)cc1 +Cc1c(-c2nc(-c3ccc(C#N)cn3)no2)cccc1N1CCNC1=O +COc1cccc(C(=O)N2CCCC(NC(C)=O)C2)c1 +Cc1ccccc1Nc1nc(N)nc(COc2cccc(C#N)c2)n1 +COc1ccccc1COC(=O)c1ccccc1N +O=C(c1ccc(Cl)cc1)N1CCC(CCOc2cccnc2)CC1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1cc(C(C)C)[nH]n1 +Cn1cc(C(=O)Nc2ccc(Cn3cccn3)cc2)c(C(F)(F)F)n1 +Cc1cccc(C(=O)N2CCCC2)c1NC(=O)NC1CC1 +CC(=O)c1c[nH]c(C(=O)NCc2ccc(-c3ccn[nH]3)cc2)c1 +Cn1ccc2c(C(=O)Nc3ccc(C(N)=O)cc3)cccc21 +CC(C)C(=O)NC(NC(=O)C(C)C)c1ccc(Br)cc1 +CCc1n[nH]c(SCC(=O)N2CCn3cccc3C2CC)n1 +Cc1c(Cl)cccc1NC(=O)c1nc2ncccn2n1 +N#Cc1ccsc1NC(=O)CCc1ccccc1 +COCc1cc(C)nc(SCC(=O)Nc2cccc(C)c2)c1C#N +CC(NS(=O)(=O)c1c(N)cc(Cl)cc1Cl)C(N)=O +O=C(COc1ccccc1)NCCC(=O)Nc1ccccc1 +Cc1ccccc1NC(=O)CN1CCN(c2ccc(O)cc2)CC1 +O=C(COC(=O)c1cc(=O)[nH]c2ccccc12)c1ccc[nH]1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)c1sccc1C1CC1 +NS(=O)(=O)c1ccc(C(=O)NCC2CCCc3ccccc32)cc1 +CCC(=O)Nc1ccc(NC(=O)C2CC=CC2)cc1 +CCCCNC(=O)NSc1nc(C)cc(C)n1 +COc1ccc(Nc2nc(N3CCOCC3)nc3c2cnn3C)cc1 +COCCNC(=O)c1cc(-c2cccs2)nn1-c1ccccc1 +COC(=O)C(NCCn1cccn1)c1ccccc1 +CC(C)Oc1ccc(NC(=O)NC(C)(C)C)cc1 +Cc1ccc(C(=O)N(C)Cc2cnc(N(C)C)nc2)cc1O +Cc1ccsc1CN1CC2COCC2(COCC(=O)N(C)C)C1 +CCNC(=O)CN1CCN(c2nnc(C(F)(F)F)s2)CC1 +Cc1ccc(CCC(=O)NCC(=O)N2CCOCC2C2CC2)cc1 +COc1cccc(C(O)CSc2ccccn2)c1 +Cc1noc(C)c1COc1ccc(C(=O)Nc2ccc(F)cc2)cc1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)Nc1nc2c(s1)CC(C)CC2 +O=C(CCc1nnc(-c2ccccc2)o1)NCCc1cccs1 +COCCCNC(=O)CS(=O)(=O)c1ccc2ccccc2c1 +CCC(=O)Nc1ncc(Cc2ccc(F)cc2)s1 +COc1cc(OC)cc(C2=NC3(CCCC3)NC2=O)c1 +O=C(Cn1c2ccccc2c2cn[nH]c(=O)c21)NC1CCCCCC1 +COCc1cccc(NC(=O)Nc2ccccc2OC)c1 +CCCc1cnc(NC(=O)N2CCCC(c3nncn3CC)C2)s1 +Cc1cc(NCC(=O)N(C)C)ccc1C(=O)NC(C)C +Cc1ccc(NS(=O)(=O)c2ccc(S(N)(=O)=O)cc2)cc1 +CCOc1cc(C)c(C)cc1S(=O)(=O)NCc1cccnc1 +CC(c1ccc(F)cc1)N(C)C(=O)c1ccc(S(N)(=O)=O)o1 +COC(=O)c1ccc2c(=O)n(-c3ccccc3)c(N3CCCC3)nc2c1 +CN1c2ccc(N)cc2N(CCO)C(=O)C12CCCC2 +Cc1csc(N2CCN(C3CC(C)OC3=O)CC2)n1 +CCc1ccc(CNC(=O)Nc2ccccc2-n2cccn2)s1 +CCc1cccc(CC)c1NCC(O)c1ccc(OC)cc1 +Cc1sc2ncnc(NC(C)c3nccs3)c2c1C +O=C(c1cc(-c2cccs2)on1)N1CCCCCC1 +CCn1cc(-c2ccc(Cl)cc2)cc1C(=O)NCc1ccncc1 +CCCCN(CC)C(=O)C1(C)Oc2ccccc2NC1=O +CCCCNC(=O)CSc1nc2ccccc2n1CC +CC(C)CC1(CNC(=O)c2ccc3c(c2)NC(=O)CO3)CCCC1 +O=C(c1ccc[nH]1)N1CCOCC2(C1)CN(c1ccoc1)C(=O)CO2 +COc1cccc2c(=O)c(C(=O)N3CCC4(CC3)OCCO4)c[nH]c12 +CSc1ccc(OC(C)C(=O)NC2CC2)cc1 +COc1ccc(F)cc1C(O)CNCc1ccc(C)cc1 +O=C(NCc1ccccc1)c1cc(Cl)ccc1F +COc1ccc(NC(=O)c2ncoc2C)cc1OC(C)C +COC(=O)CCCN(C)C(=O)c1sccc1-n1cnnn1 +Cc1ccc(NC(=O)NCc2ccc(S(C)(=O)=O)cc2)c(F)c1 +CN(c1ccccc1)S(=O)(=O)c1ccc2c(c1)C(C)(C)C(=O)N2 +NS(=O)(=O)c1cccc(CNC(=O)c2cc(Cl)ccc2O)c1 +C=CCc1c(C)nc(N)nc1N1CCOC2(CCCC2)C1 +Cc1ccc(OCC(=O)NCCCc2ccccc2)nc1 +Cc1oc2cc(O)ccc2c(=O)c1-c1ccc2ccccc2n1 +Cc1n[nH]c2ncc(C(=O)N3CCN(Cc4ccccc4)CC3C)cc12 +Cc1ccc(Cl)c(OCC(=O)Nc2ccccc2C(N)=O)c1 +CCNC(=O)C(C)NC(=O)COc1cc(C)ccc1C +CN(C(=O)CSc1nnc(-c2cccnc2)o1)C1CCCCC1 +CC(=O)N1CCc2cc(NC(=O)Cn3c(C)csc3=O)ccc21 +O=C(NCC1CCN(c2ccccc2)C1)c1ccc(-n2cncn2)nc1 +Cc1cccc(C(=O)NCC(=O)NCC(=O)Nc2ccc(F)cc2)c1 +O=S(=O)(Cc1c(F)cccc1Cl)NCc1ccccc1 +COC(=O)NCC(=O)N(Cc1ccco1)Cc1cccs1 +NC(=O)c1ccccc1OCC(=O)c1c[nH]c2ccccc12 +O=C(Nc1nnc(-c2ccc3c(c2)OCCO3)o1)c1cccs1 +Cc1csc(C(C#N)C(=O)C2(c3cccc(F)c3)CCC2)n1 +N#Cc1cccnc1NCC(=O)N1CCN(c2ccccc2)CC1 +COc1ncccc1C(=O)N1CCC(Oc2cccc(Cl)c2)C1 +CC(C)n1nccc1NC(=O)Cn1ccc(-c2ccccc2)n1 +O=c1cnc2cc(Cl)c(Cl)cc2n1CCO +COc1ccc(Br)c(C(=O)OCC(=O)c2ccc[nH]2)c1 +CC1(NC(=O)NCCC(=O)Nc2ccccc2)Cc2ccccc2C1 +O=C(c1ccc2[nH]cnc2c1)N1CCN(CCn2cccn2)CC1 +COC(=O)c1ccc(Cl)c(N(C)C(=O)CC#N)c1 +COC(=O)CN(Cc1cc(=O)oc2c(C)c(O)ccc12)C(C)C +COCC(C)NS(=O)(=O)c1cc(C(F)(F)F)ccc1Cl +CCCn1nc(C(=O)OC2CCOC2=O)c2ccccc2c1=O +O=C(NCc1ccco1)c1ccc(-n2ccnn2)cc1 +COc1ccccc1CNC(=O)COc1ccccc1CO +COc1ccc(C)cc1NC(=O)C1CCN(C(N)=O)CC1 +CCCC(=O)NC(c1ccccn1)c1ccccc1OC +CN(Cc1ccc2c(c1)OCCO2)C(=O)NCC1CCCO1 +CC(CNC(=O)c1csc2c1CCCC2)Cn1cccn1 +O=C1CCC2C(CCN2S(=O)(=O)c2cccs2)N1CC1CC1 +Cn1cccc(C(=O)N(Cc2ccsc2)C2CC2)c1=O +CC(C)CCC(=O)N1CCN(c2ncc(C#N)cc2Cl)CC1 +Cc1cncc(C2CCN(C(=O)Cc3csc(C)n3)CC2)n1 +COc1ccsc1C(=O)NC(C#N)c1ccc(F)cc1F +CSc1ccc(C(=O)NC2CCSc3ccccc32)cc1 +CCC1CCCN(C(=O)c2ccc(F)c(N)c2)C1 +CCc1cccc2sc(NC(=O)NCCOC)nc12 +CC(C)CC1(CNC(=O)C2CCN(c3cnccn3)CC2)CCCC1 +CC(NC(=O)NCc1cnn(C)c1)c1ccc(-n2ccnc2)cc1 +CC(Cc1ccco1)NC(=O)c1cc2ccccc2oc1=O +CC(Sc1nnc(N2CCCCC2)n1-c1ccccc1)C(N)=O +COc1ccc(COC(=O)CCn2c(=O)oc3ccccc32)cc1 +CCn1cc(S(=O)(=O)NC(C)COC)c(N)n1 +O=C(NCC(=O)N1CCc2ccc(Cl)cc2C1)c1ccccc1 +COc1c(C)cnc(CNC(=O)N2CCC(n3cccc3)CC2)c1C +Cc1ncc(N)c(-c2ccccc2Br)n1 +CC(=O)N1CCC(NC(=O)c2n[nH]c(=O)c3ccccc23)CC1 +COc1ncccc1CNC(=O)c1ccnc(-n2ccnc2)c1 +Cc1ccc(N)c(OCC(=O)N2CCN(C)CC2)c1 +O=C(Cc1ccc(Cl)cc1Cl)NCC(CO)Cc1ccco1 +Cc1cnc(C(=O)N2CCOC(c3nc(C)n[nH]3)C2)cn1 +O=S(=O)(Cc1noc2ccccc12)N1CCc2c(F)cccc2C1 +CCNC(=O)N1CCN(Cc2cc(=O)oc3cc(CC)ccc23)CC1 +O=C(CO)N1CCN(C(=O)c2cc(Cl)ccc2OC(F)F)CC1 +COC(=O)C(C)CNC(=O)Nc1cnn(C(C)C)c1 +CCOC(=O)c1ccc(NC(=O)Cc2ccc(C)nc2)cc1 +O=C(NC(O)C(=O)c1ccc(F)cc1)c1ccccc1 +Cn1cc(NC(=O)Nc2ccc3c(c2)OC(C)(C)O3)cn1 +CC(c1cncs1)N(C)C(=O)c1c[nH]nc1-c1ccccc1 +Cc1ccc(C(=O)N2CCCC(c3nccn3CC(N)=O)C2)cc1 +CC1CN(S(=O)(=O)CCOC(C)C)C(C)(C)C1 +O=C(c1cc(-c2ccccc2)n[nH]1)N1CC(c2nc(C3CC3)no2)C1 +Cn1c(SCc2nc3ccccc3c(=O)n2C)nnc1C1CC1 +CCNc1nnc(SC(C(=O)N2CCCC(C)C2)C(C)C)s1 +OCC1CCCN1c1cc(NC2CCc3c(F)cccc32)ncn1 +c1cc(-c2nnc3sc(-c4ccsc4)nn23)ccn1 +Cc1cc(Cl)c2[nH]cc(Br)c(=O)c2c1 +CCN1C(=O)C(C)(C(=O)Nc2cccc(C)n2)Oc2ccccc21 +CC1CN(CC(=O)Nc2nncs2)CCN1c1nccs1 +NC(=O)c1cncc(-c2ccccc2OCc2ccccc2)c1 +COC(=O)N1CCN(C(C)C(=O)Nc2ncccn2)CC1 +COCCn1cc(NC(=O)N(C)CC(C)C)cn1 +C=CCSc1nnc(NC(=O)c2snnc2C)s1 +N#Cc1c(F)cccc1S(=O)(=O)N1CCc2cc(F)ccc2C1 +COCCOc1ccccc1NC(=O)NCc1cccc(C#N)c1 +Nc1cc(F)ccc1NS(=O)(=O)c1ccccc1Cl +Nc1c(-c2ccccn2)nc2scc(-c3ccncc3)n12 +CNC(=O)c1cccc(NC(=O)c2cc3ccccc3o2)c1 +CCn1nnnc1NCc1cccc(OCc2ccccc2F)c1 +Cc1cc(C(=O)N2CCN(Cc3ncc(C(C)(C)C)o3)CC2)on1 +CCOCCNC(=O)c1cc2ccccc2cc1O +O=C(CCCN1Cc2ccccc2C1=O)Nc1ccccn1 +CC(=O)c1nnn(CC(=O)Nc2ccc3c(c2)OCO3)c1C +COc1ccc2[nH]cc(CC(=O)Nc3nc(C(C)C)cs3)c2c1 +CC1(C)CC(=O)C2(Cc3ccccc3N3CCCCC32)C(=O)C1 +COc1ccccc1CNC(=O)c1cn2c3c(cccc3c1=O)CC2 +Cc1cc(N)nc(COc2ccc(F)c(F)c2)n1 +NC(=O)CCCNC(=O)Nc1ccccc1SC(F)F +CC(C)C1CN(C(=O)Nc2cccc(Br)c2)CCO1 +CCOc1coc(C(=O)Nc2nc3ccc(C)cc3s2)cc1=O +CC(C)C1NCCc2c(Cl)cc3c(c21)OCCO3 +Cc1ccc2[nH]cc(NC(=O)NCC3CC3)c(=O)c2c1 +Cc1ccc(N2CCCN(C(=O)c3cnc(C)s3)CC2)nn1 +CN(C)C(=O)N1CCN(C(=O)Nn2cnc3ccccc32)CC1 +CC(C)(C)OC(=O)N1CCC(Oc2ccccc2)(C(N)=O)CC1 +CN(C(=O)Nc1ccncc1)C1CCc2ccccc21 +CCOC(=O)C1CCN(C(=O)C(C)n2nc(C)ccc2=O)CC1 +Cc1csc(C(C#N)C(=O)c2cccc(S(C)(=O)=O)c2)n1 +CCOc1cccc(OCCCn2ccc(N)n2)c1 +O=C1CCCN1CCC1CN(Cc2n[nH]c(=O)[nH]2)c2ccccc21 +COCCNc1nc(C)c(C(=O)NCC(C)C)s1 +O=C(C1CCCC1)N1CCC(n2nc(-c3ccccc3)oc2=O)CC1 +N#Cc1nnn(-c2cccc(Br)c2)c1C1CC1 +COc1ccc(-c2cc(N3CCOCC3)ncn2)c(OC)c1 +Cc1cc(N)cc(C(=O)OCc2cccs2)c1C +CC(=O)NCc1ccc(S(=O)(=O)NC2CCCC2)cc1 +CC(C)c1cncc(Br)c1OC1CC1 +CC(C)(CCC(=O)OC(C)(C)C)NC(=O)C1CCC(=O)N1 +Cc1ncc2c(n1)CCCC2NC(=O)c1cc(C2CC2)nn1C +CCNC(=O)CSc1nnc(-c2ccccc2OC)n1N +Cc1cccc(C)c1NC(=O)c1cnc(C(C)(C)C)cn1 +Cn1nc2n(c1=O)CCN(C(=O)Nc1ccccc1F)C2 +CCc1noc(CC)c1CNC(=O)c1cc(F)ccc1O +CN(CCc1ccc(F)cc1)C(=O)c1ccccc1Cl +Cn1c(C(=O)OCCNc2cccnn2)c(Cl)c2ccccc21 +Cc1ccc(CNC(=O)c2ccc(N)cc2Cl)cc1 +COc1ccc(-c2nccc(=O)[nH]2)cc1Br +COc1cccc(OCC(=O)N2CCN(c3nccn3C)CC2)c1 +CCn1nc(C(=O)NCc2cccc(F)c2)c(=O)c2cc(F)ccc21 +CCCOc1cc(C(=O)NCc2ccc(C)cc2)ccc1N +CCSc1ncc(S(=O)(=O)c2cccs2)c(N)n1 +Cc1ccnc(NC(=O)C2COc3ccccc3O2)c1 +CCCN(CCC)C(=O)CSc1nc2ccccc2c(=O)n1N +COc1ccc(OC)c(NC(=O)c2cc(F)cc(F)c2)c1 +O=C(NCCCNc1ncccn1)c1cc(Cl)ccc1Cl +CCC(=O)Oc1cccc(NC(=O)c2ccc(C)cc2)c1 +CC(=O)Nc1ccc(NC(=O)Nc2cccc(Cl)c2C)cc1 +Cc1ccc(C(C)C)cc1OCC(=O)N1CCCC1C(N)=O +Cn1nnn(-c2ccc(NC(=O)Cc3ccccc3Cl)cc2)c1=O +CCCOC(=O)C(C)Sc1nnc(C)n1CC +Cc1ccc(C(=O)Oc2ccc(N(C)S(C)(=O)=O)cc2)s1 +Cc1ccc(NC(=O)N(C)C)c(C(=O)N(C)CCOCC2CC2)c1 +Cc1cc(Br)ccc1OCC(=O)NCCO +CNC(=O)NCC(=O)N(C)C(C)c1ccc(OC)cc1 +O=C(c1ccc2c(c1)OCO2)N1CCn2ncnc2C1 +CC(=O)N1CCc2cc(Nc3cccc(N(C)C)c3)ccc21 +CCc1nc(C(=O)NC(C)c2ccccc2)sc1C +CCn1ncc(C(=O)N2CCN(CC3CCCO3)CC2)c1C +CC1(C)CCC(Cc2ccc(Cl)cc2)C1(O)Cn1cncn1 +NC(=O)COC(=O)Cn1cnc2scc(-c3cccs3)c2c1=O +CCc1c(C(=O)OC)cnn1-c1nc2ccc(OC)cc2s1 +CN(C(=O)C1CC(=O)N(Cc2ccco2)C1)C1CCCCC1 +CC(C)(C)OC(=O)Nc1ccc(CC(=O)NCC2CCOC2)cc1 +O=C(NC1CCC(O)CC1)C1CCCN1C(=O)C1CCCCC1 +Cc1ccc2c(c1)C(NCc1ccccn1)C(=O)N2 +CCn1c(SCc2ccon2)nc2ccccc2c1=O +COc1ccc(F)cc1NC(=O)c1cc[nH]c(=O)c1 +O=C(NCC(c1cccnc1)S(=O)(=O)c1cccs1)C1CC1 +COc1ccc(OC)c(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1 +CCOCCCNC(=O)Cc1coc2c(C)c(C)ccc12 +Cc1noc(C)c1CSc1nc(-c2ccncc2)nc2c1CCC2 +CNC(=O)CCCC(=O)c1ccc(OC)c(C(C)C)c1 +CC(C)N(C)S(=O)(=O)NC1CC1c1ccccc1Br +O=C(Cn1cnc(C2CCC2)cc1=O)N1CCCCC1 +NC(=O)c1ccc2nc(-c3ccccc3)sc2c1 +CCOc1cc(C2Nc3ccccc3C(=O)N2C)ccc1O +CCC1COCCN1Cc1ccc(Oc2cnccn2)cc1 +O=C(Oc1cccnc1)c1ccccc1Br +CCn1cnnc1CNC(=O)CCc1ccc(-c2ccccc2)o1 +CCN1C(=O)CCCC12CCCN(C(=O)c1ccc(OC)cc1)C2 +Cc1ccc2c(c1)N(C(=O)c1ccc(OCC(F)F)nc1)CC(C)O2 +CC(C)CC(C)n1nccc1NC(=O)c1cccc2c1OCC(=O)N2 +COc1cc(NCc2c[nH]nc2-c2cccnc2)cc(OC)c1 +CNC(=O)c1cccc(NC(=O)NCC(C)Cn2cccn2)c1C +CCSc1nnc(NCc2cccs2)s1 +CCOC(=O)C1CCCN(c2cc(F)ccc2OC)C1 +Cc1csc(CNC(=O)c2cc(C)n(-c3cccnc3)c2C)n1 +Cc1cnn(C2CCCN(C(=O)Cc3cn4cccc(C)c4n3)C2)c1 +CN(C)c1ccc(Cl)cc1NC(=O)NCc1nncn1C1CC1 +O=C(C1C2CC1N(C(=O)c1ccco1)C2)N1CCOCC1 +Cc1ccc(S(=O)(=O)NC(=O)Nc2cc(F)ccc2F)cc1 +CNC(=O)c1ccc(S(=O)(=O)NCCC(C)(C)C)cc1 +CSc1ccc(C)c(C(=O)OCCOC(C)C)c1 +COc1ccc(CN(C(=O)c2ccn(C)c(=O)c2)C2CC2)cc1 +Cc1nc(N2CCCC2CO)c2cnn(-c3cccc(Cl)c3)c2n1 +CCn1c(C(=O)NCc2ccncc2)cc2cc(NC(C)=O)ccc21 +O=C(CCN1C(=O)CCc2ccccc21)Nc1nnc(C2CC2)s1 +Cc1ncn(CCNC(=O)Nc2ccccc2)c(=O)c1C +Cc1noc(N)c1C(=O)OC(C)c1nc2ccccc2c(=O)[nH]1 +O=C(NC1CC1)c1cn2c(n1)CN(C(=O)c1ccc(F)cc1)CC2 +COC(=O)Nc1ccc(NCc2scnc2C)cc1F +CC(=O)Nc1ccc(NC(=O)NCC(C)(O)c2ccsc2)cc1 +Cn1ccc2c(C(=O)NCc3ccc(S(N)(=O)=O)cc3)cccc21 +Cc1cc(NC(=O)N2CCC(C)CC2)c2ncccc2c1 +Cc1cc(CNc2cnn(-c3ncccn3)c2)c(C)o1 +CCC1CCC(O)C(CN2CCOC(CC)C2)C1 +Cc1cccc(-c2nnc3sc(NC(=O)c4ccco4)nn23)c1 +COc1ccc(C)cc1NC(=O)Cn1c(C)ccc(C#N)c1=O +CCOc1ccc(C)cc1S(=O)(=O)n1cc(C)nc1CC +Cc1ccc(C(=O)NCC(=O)NCc2ccoc2)s1 +COc1ccc(-n2nc(C)c3c(=O)c4c([nH]c32)CCCC4)cc1 +Cc1cc(=O)c(CC#N)nn1-c1ccc(F)c(F)c1 +CN(C(C#N)c1ccco1)S(=O)(=O)c1cccc(Cl)c1 +COC(=O)CCNC(=O)CNC(=O)c1ccc(C)cc1 +Cc1ccc(NC(=O)c2c(C)cc(C)[nH]c2=O)c(C)c1 +O=C(CCC(=O)N(Cc1ccccc1)C1CC1)c1cccs1 +Cc1nnc(SCc2ccc(F)c(F)c2)n1N +Cc1ccc(Cn2nc(C)c(C(=O)Nc3cccnc3)c2C)cc1 +COC(=O)c1nnc2c(-c3ccccn3)ccnn12 +Nc1cccc(-c2cc(=O)[nH]c(-c3ccccc3Cl)n2)c1 +COC(=O)CCC(=O)NC1CCCc2[nH]c(=O)ccc21 +Cc1cc(C)c(S(=O)(=O)N2CCNCC2)cc1C +CN(C(=O)c1ccccc1)C(C#N)c1cccs1 +CN(C)S(=O)(=O)c1ccc(CS(=O)(=O)c2ccccc2F)o1 +O=C(c1ccc(NC2CCC2)nc1)N1CCC(Cn2cccn2)CC1 +Cc1nc(-c2noc3ccc(C(=O)NCc4ccccn4)cc23)co1 +CC(=O)Nc1ccc(NC(=O)c2ccc(C(C)(C)C)cc2)c(O)c1 +CC(C)C(=O)Nc1cccc(C(=O)Nc2nccs2)c1 +CC(NC(=O)c1ccccc1)C(=O)NCC1(c2ccccc2)CC1 +COC(=O)C(O)(c1ccccc1)C1C(=O)N(C)c2ccccc21 +NC(=O)C1CCCCC1C(=O)N1CCc2ccccc21 +FC(F)(F)Cn1cnc2cc(C(F)(F)F)ccc21 +CCn1nccc1C(=O)NCC1(N2CCOCC2)CCCCC1 +COCCCC(=O)N(C)CC(=O)Nc1c(C)cc(C)cc1C +COc1ccccc1OC(=O)C1CC(=O)N(c2ccccc2Cl)C1 +COc1ccc2[nH]cc(C(=O)N3CCC(C)CC3)c(=O)c2c1 +O=C1CN(C(=O)c2sccc2Br)CCN1 +Cc1nnc(SCc2ccc(Br)cc2F)s1 +CSc1ncc(CN2CC3(CCOC3)CCC2=O)n1C +CNC(=O)CSc1nnc(-c2ccc(OC(F)F)cc2)n1N +OC1Cc2ccccc2C1Nc1ncnc2sc3c(c12)CCNC3 +CC(CNC(=O)C(C)NC(=O)C(C)(C)C)Oc1ccccc1 +CC1CC(C)CN(C(=O)COC(=O)c2ccc(O)cc2)C1 +CCN1C(=O)C(c2ccccc2)Oc2ccc(C(=O)C(C)N)cc21 +O=C(Cn1ccc(=O)[nH]c1=O)NCC1CCCCO1 +CCOc1cccc(NC(=O)c2cc(S(C)(=O)=O)ccc2C)c1 +Cc1ccc(C(=O)N2CCN(S(=O)(=O)C(C)C)CC2)s1 +Cc1nc(-c2ccc(CCNC(=O)c3ccc(O)nc3)cc2)cs1 +CNC(=O)COc1ccc(C(=O)Nc2ccccc2Cl)cc1OC +COc1cccc(C(=O)Nc2cccc3c2OCCO3)c1F +Cc1ccoc1C(=O)N(C)Cc1nc2ccccc2[nH]1 +C=CCN(CC1CCCCC1)C(=O)c1cnn(-c2ccncc2)c1C +CC(C)c1noc(C2CC(=O)N(Cc3ccccc3)C2)n1 +CC(c1ccc(F)cc1)N(C)C(=O)c1cc(C2CC2)[nH]n1 +CCc1onc(C)c1NC(=O)NC(C)c1cc(C)oc1C +CCc1cc(NC(=O)NCCOc2ncccc2Cl)n(C)n1 +COc1cccc(C(=O)OCc2nnc(-c3ccccc3)o2)c1F +CC(=O)N(C)CC(=O)Nc1ccccc1C(=O)C(C)C +CC1CCN(c2cncc(Br)c2)CC1 +CCCNC(=O)Cn1nc(C)n2c(cc3sccc32)c1=O +CCC(NC(=O)c1cc2ccccc2oc1=O)c1nc(C)cs1 +CNC(=O)C1CCCN(C(=O)c2cnc3ccc(C)cn23)C1 +COCCOc1ccccc1NC(=O)c1cc(C(C)(C)C)n[nH]1 +O=C(NCCCn1ncccc1=O)c1ccc(Cl)cc1 +CC(NC(=O)N1CCCC1)c1ccc(S(N)(=O)=O)cc1 +Cc1cc2nc(CN3Cc4ncccc4C3=O)[nH]c2cc1C +COc1ccc(CNC(=O)N2CCC(C)CC2)cc1F +CC(C)c1csc(NC(=O)C2CCOc3ccccc32)n1 +CN(C)c1ccc2c(c1)S(=O)(=O)N=C(NC(C)(C)C)N2 +C=C(C)Cn1c(=O)c2c(nc3n(CCCOC)c(C)cn23)n(C)c1=O +Cc1ccc2c(c1)CCNC2CN(C)C(=O)OC(C)(C)C +O=C1CCCN1CC1CCCC2(CCN(S(=O)(=O)C3CC3)C2)O1 +Cn1c(=O)oc2c(C(=O)N3CCc4cc(F)ccc4C3)cccc21 +Cc1nc(=O)[nH]c(C)c1CCC(=O)N1CCCc2ccccc2C1 +N#CCOC(=O)c1ccc(S(=O)(=O)N2CCCCCC2)cc1 +O=C(CC1(Cn2cnnn2)CCCCC1)Nc1ccncc1 +COC(=O)c1cc2oc(C)cc2n1Cc1cc(=O)n2ccccc2n1 +N#Cc1ccc(C(=O)Nc2ccc(Cl)cn2)c(F)c1 +CC(=O)c1ccc(C(=O)c2ccc(C(C)=O)s2)s1 +CC1CCCN(S(=O)(=O)CCNC(=O)c2ccccc2)C1 +COc1cc(OC)cc(C(=O)NC2CCN(C(=O)CC(C)C)CC2)c1 +COCCCNC(=O)c1cn(C)c(=O)c2c1c1ccccc1n2C +O=S(=O)(NCc1cccc(F)c1)c1ccc2c(c1)OCCCO2 +Cc1ccc(C(=O)N(Cc2ccccn2)C2CC2)c(=O)[nH]1 +NC(=O)COc1cccc(Cn2ccccc2=O)c1 +CCN1CCN(C(=O)c2cncc(-c3ccccc3C)c2)CC1 +Cc1ccc(-c2nc(Cn3cnc4onc(C)c4c3=O)c(C)o2)cc1 +O=C(CCC(=O)N1CCOc2ccccc21)c1ccc(F)c(F)c1 +CCOc1ccc(NC(=O)CCNC(=O)c2ccc(Cl)cc2)cc1 +COCC(C)NC(=O)N1CCN(S(C)(=O)=O)CC1 +Nc1nc(N)nc(COc2ccc(F)cc2Br)n1 +Cc1ccccc1NCCC(=O)NCc1ccc2c(c1)OCO2 +CN(C)C(=O)CN(CC(F)(F)F)C(=O)Cn1ncc2ccccc21 +O=C(NCCNc1ncccn1)C1CCN(C(=O)N2CCCC2)CC1 +C=CCOc1ccc(C(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)cc1 +CC(=O)Nc1cccc(C(=O)Nc2ccc(Cl)cc2F)c1 +COC(=O)C(CC(C)C)NC(=O)Cc1ccc(Cl)cc1 +COc1cccc(-c2nnn(CC(=O)Nc3ccc(F)c(F)c3)n2)c1 +CCc1noc(CC)c1CC(=O)Oc1ccc(OC)c(F)c1 +CCOC(=O)c1noc2nc(C)n(Cc3ccc(C)cc3)c(=O)c12 +CCn1cnc2cc(NS(=O)(=O)c3ccc(C)cc3)ccc21 +CCC(CO)N(Cc1ccco1)C(=O)c1c[nH]c2ccccc12 +COC1COC2(CCN(Cc3nccs3)CC2)C1 +Cc1ccc(NC(=O)C2CC2)cc1NC(=O)NC(C)CCCO +NS(=O)(=O)Nc1cccc(NC(=O)Cc2cccc(F)c2F)c1 +Cc1cc(C(=O)Nc2nc(C3CC3)cs2)c(C)n1-c1nccs1 +CC1CN(CC(O)Cn2nc(-c3ccco3)oc2=O)CC(C)O1 +CC(=O)N(CCc1ccccc1)CC(=O)N1CC2CCCC2C1 +COc1ccc(C(NC(=O)c2cc(=O)[nH]c(C)n2)c2ccccc2)cc1 +CCS(=O)(=O)N1CCCC1c1ccc(OC)cc1 +COC(=O)c1ccc(C)c(NC(=O)CNC(=O)C2CCCCC2)c1 +CCCCN(C)S(=O)(=O)N1CCOC(C)(C)C1 +O=C1OC(c2ccccc2)N=C1Cc1ccc(O)cc1O +Cc1ccc(C)c(-n2nnnc2SCC(=O)NCC2CCCO2)c1 +CC(C)(CNC(=O)C1(Cc2ccccc2)CCC1)NS(C)(=O)=O +Cc1cc(C(=O)OC(c2nccn2C)C(C)C)cc(=O)[nH]1 +COc1ccc(NC(=O)Nc2ccc3c(c2)C(=O)N(C)CCO3)cc1 +Cc1occc1CN(C)S(=O)(=O)c1ccc(N)cc1 +Cc1nc(-c2cccc(NC(=O)c3ccccc3F)c2)cs1 +NC(=O)COc1coc(CN2CCN(c3ccccc3)CC2)cc1=O +Cc1nc(Cn2c(N)nc3ccc(F)c(F)c32)cs1 +CC(C)C(NC(=O)c1ccc(Cl)cc1Cl)C(=O)OCC(N)=O +COC(=O)CN(Cc1ccc(C(=O)N(C)C)[nH]1)C1CCCC1 +Cc1ccncc1NC(=O)NC1CCN(S(C)(=O)=O)CC1 +Cc1cccc(N(C)S(=O)(=O)c2ccc(-n3cccn3)cc2)c1 +CC(C)(C)c1csc(CC(=O)c2ccc(N)cc2)n1 +Cc1cc(NC(=O)C2CCC(=O)N2Cc2ccc(C)o2)no1 +CC1CN(CCC(O)c2ccc3c(c2)CCCN3)CC(C)O1 +CC(C)CC(C)N(C)C(=O)c1cccc(F)c1F +Cc1ccc2ncc(C(=O)Nc3cccc(-c4nncn4C)c3)n2c1 +N#Cc1ccc(C(=O)N2CCN(Cc3ccccc3)CC2)c(F)c1 +COc1cc(CNC(=O)CCc2cnn(-c3ccccc3)c2)ccn1 +O=C(NCCC1=CCCCC1)NCc1ccc(-n2cccn2)cc1 +CC(c1ccco1)N1CCN(C(=O)OC(C)(C)C)CC1 +CN(Cc1nccn1C(F)F)C(=O)c1cccc(Cl)c1Cl +COC(=O)c1cccc(NC(=O)NCc2cccc(C)c2)c1 +COc1ccc(Cn2ncc3ccc(N)cc32)cc1 +CC(NC(=O)Cn1cc(C(F)(F)F)ccc1=O)C1CCCCC1 +O=C(CCNC(=O)c1ccccc1)Nc1ccn(Cc2ccncc2)n1 +Nc1cc(NC(=O)CCSc2nncs2)ccc1F +Cc1ccc(Nc2ccc(C(=O)N3CCCCC3)cn2)cc1 +COc1ccc(-n2ccc(CNC(=O)Nc3cccc(C#N)c3)n2)cc1 +O=C(Cc1c[nH]c2ccccc12)OCC1COc2ccccc2O1 +CCc1nc(NC(=O)Cn2nc3c(cc2=O)CCCC3)sc1C +CCc1ccccc1NCC(=O)c1ccc(OC)c(OC)c1 +CC(NC(=O)c1ccccc1-c1ccccc1C#N)c1ccncc1 +Cc1cnn(CC2CCCN2C(=O)c2ccsc2)c1 +CC(C)NC(=O)c1ccc(OCC2CCCO2)cc1 +COCC(=O)N(C)CCOc1ccc(Br)cc1 +CN(C)c1ccc(-c2noc(CCNC(=O)C3CCC3)n2)cc1 +CN(CC(=O)N1CCc2ccccc21)c1ccc(N)cn1 +CN(Cc1ccoc1)C(=O)c1cn2ccccc2n1 +COc1cccc(F)c1C(O)c1ccc(F)cc1 +O=C(CC1CCCC1)Nc1ccc2c(N3CCOCC3)ncnc2c1 +Cc1cc(C)n(C(C)CC(=O)Nc2ccc(Cl)cc2)n1 +O=C(Cc1ccc(O)cc1Cl)NC(CO)Cc1ccccc1 +Cc1cccc(N(CCC(N)=O)Cc2ncc(C(C)(C)C)o2)c1 +Nc1nccnc1C(=O)NCc1ccc(OCC(F)(F)F)cc1 +CCOC(=O)c1ccc(OC(=O)CC2C=CCC2)cc1 +CC(=O)Nc1ccccc1OCC(=O)N(C)Cc1ccsc1 +Cc1ccc(C(=O)NC(C)COC2CCOC2)c(O)c1 +Cc1ccccc1OC(=O)C1CCN(C(=O)C(C)C)CC1 +O=C(CCNC(=O)NC1CCCCC1)Nc1nncs1 +CC1CCN(C(=O)CNc2ccccc2OCC2CC2)CC1 +CN(Cc1cccs1)C(=O)CN1CCn2c(nn(C)c2=O)C1 +CN(Cc1cccc(O)c1)C(=O)c1ccc(Br)c(F)c1 +COc1ccc2c(C)c(C(=O)NCCc3cccnc3)oc2c1 +Fc1cc(NCc2noc(C3CC3)n2)ccc1Cl +CC1=C(C)CS(=O)N(S(=O)(=O)c2ccc(Cl)cc2)C1 +N#CC(CCC(=O)Nc1cccc(Cl)c1)c1cccnc1 +COc1ccccc1C(CC(C)C)NC(=O)Nc1cnccc1C +CCc1cccc(NC(=O)NC2CCN(c3ccccc3)C2=O)c1 +Cc1cc[nH]c(=O)c1C(=O)N1CCN(CC(F)(F)C(F)F)CC1 +CCCCCCNS(=O)(=O)c1ccc(N)cc1 +O=C(Nc1cc(-c2ccncc2)n[nH]1)c1cnc2ccccc2n1 +COc1ccc(-c2nc(-c3ccc4c(c3)oc(=O)n4C)no2)cc1 +COc1cc(C)ccc1OC(=O)Cc1ccccc1F +CCc1cc(C(=O)NCCc2ccc(O)cc2)sc1C +CC1Cc2cc(S(N)(=O)=O)ccc2N1Cc1ccc(F)cc1F +Cc1n[nH]c(SCC(=O)c2cccc3ccccc23)n1 +Cc1cccc(OCC(=O)Nc2ccc(F)c(F)c2)c1 +COCc1cc(C)nc2sc(-c3nnc(C)o3)c(-n3cccc3)c12 +CCC1CCCN(C(=O)Cc2csc(-c3cccnc3)n2)C1 +CC(C)N1CCCC2(CCN(C(=O)c3cc(C#N)cn3C)C2)C1=O +NC(c1ccc(O)c(Cl)c1)c1ccccc1F +Cc1nc(-c2cccc(CNC(=O)c3ccccn3)c2)n[nH]1 +CC(NC(=O)CCNC(=O)Cc1ccccc1)C1CC1 +CNC(=O)C(NC(=O)C1(C#N)CCCC1)c1ccc(F)c(F)c1 +CC(C)(C)c1ccc(NC(=O)c2cn3cccnc3n2)cc1 +CC(C)CC(=O)Nn1cnc2c(cnn2-c2ccccc2)c1=O +CCCCN(C)S(=O)(=O)c1cc(S(C)(=O)=O)ccc1Cl +COc1ccc(CNC(=O)N2CCC(C)CC2)cn1 +COc1ccc(CCn2c(C)nc3ccccc3c2=O)cc1OC +NC(=O)CCn1ccc(NC(=O)c2cccc(F)c2)n1 +CCCCN(C)C(=O)CCC(O)c1cccc(N)c1 +CN(CC1CCCCC1)C(=O)Cn1cc(Cl)c(=O)[nH]c1=O +Cc1nnc(SC(C)C(=O)Nc2cccc(Cl)c2C)s1 +O=C(c1ccnc(OC2CCC2)c1)N1CCCC1c1ccco1 +O=C(NCCCn1ncccc1=O)c1cc2ccccc2[nH]1 +CC1CCCCN1C(=O)c1ccc(CSc2nccn2C)o1 +CNS(=O)(=O)c1ccc(NC(=O)c2cccnc2)cc1 +CC1CN(C(=O)CN(C)c2ncnc3[nH]cnc23)CC(C)(C)O1 +Cc1c(NC2(C#N)CCCCC2)c(=O)n(-c2ccccc2)n1C +COc1ccc(CCC(=O)Nc2ccnn2CC(C)C)cc1F +COCCn1nc(C(=O)Nc2c[nH]nc2C)ccc1=O +NC1=NC(=O)C(Cc2ccco2)(c2ccc(-c3ccccc3)cc2)N1 +Cc1cccc(NC(=O)NCC#Cc2ccc(C(N)=O)cc2)c1 +COCCCn1cnnc1C(C)Nc1ncnc2c1c(C)nn2C +O=C(COc1ccc(F)cc1Cl)NCC1CC1 +Cc1cc(C(=O)Cn2cnc3ccccc3c2=O)c(C)s1 +CCCCCN(C(=O)c1cc(C(N)=O)cs1)C(C)C +Cc1ccc(N(CCC#N)C(=O)CNc2ccc(C#N)cc2)cc1C +COc1ccc(NC(=O)c2cccc(N(C)C)c2)cn1 +O=c1c2nnc3ncnn3c2ccn1-c1ccc2[nH]ccc2c1 +COc1ccc(C(=O)CCC(=O)NCc2cccnc2)cc1 +CS(=O)(=O)NCC(=O)NCCc1ccc(Cl)cc1 +Cn1c(SC(C(N)=O)c2ccc(F)cc2)nnc1-c1ccccc1 +COc1cc(CNC(=O)CSc2ncn[nH]2)ccc1C +CC(CNC(=O)c1c[nH]nn1)Sc1ccc(Br)cc1 +CCOCC1CCCN(C(=O)c2cccc(C#N)c2)C1 +O=C(C1CC(=O)N(C2CCCC2)C1)N1CCc2cc(F)ccc2C1 +Cc1ccccc1-c1nnn(CC(=O)NCCCc2ccccc2)n1 +COc1ccc(Cl)cc1NCC(=O)NCC1CC1 +COc1ccc2c(c1)OCC(CNC(=O)c1c(C)cc(C)[nH]c1=O)C2 +CC(NC(=O)NCCc1cccnc1)C(=O)NCc1ccccc1 +CCN1C(=O)NC(c2ccc(O)cc2)C(C(=O)OC)=C1C(C)C +COc1ccc2c(c1)nc(CCO)n2Cc1cccnc1N +O=C(NCc1ccccc1)c1nccn1-c1ccccn1 +CCN(CC)C(=O)C(Cc1ccc(F)cc1)c1cccc(N)c1 +O=C(OCc1cccnc1)C1CC1c1ccc(F)cc1 +CCc1ccc(NC(=O)NC(C)c2ccc(S(C)(=O)=O)cc2)cc1 +Cc1cc(C)c(CNC(=O)C(C)NC(=O)c2ccco2)c(=O)[nH]1 +NC(=O)C1CCN(C(=O)C2(c3ccc(Cl)cc3)CCC2)C1 +COC(=O)C(C)NCc1cc(=O)n(C)c(=O)n1C +N#Cc1cc(C(=O)Nc2ccccc2)c(N)nc1SCC(N)=O +CC1CCCC(C)N1C(=O)CSc1nnc(-c2cccs2)o1 +Cc1nc2nc(SCC(=O)NC(C)(C)C)nn2c(C)c1C +CNc1ncc(C(=O)NCCc2cccc3cccnc23)s1 +C#Cc1cccc(N(C)C(=O)Cc2c(C)nc3cc(=O)[nH]n3c2C)c1 +COCc1cc(NCc2ccc(Cl)cc2)nc(C)n1 +Cc1cccc(C)c1OCCNC(=O)CN(C)C(=O)c1ccco1 +CC(=O)NCCC(=O)NC1(CO)CCCC(C)C1 +COCCN1CCN(C(=O)NC2CCCCC2)CC1 +O=C(Nc1ccc(Oc2cnccn2)cc1)c1cnccn1 +CCOC(=O)C1CC2(C(=O)N(C)c3ccc(F)cc32)N2CCCC12 +COc1cc(C(=O)NCCN2CCOCC2)cc2occc12 +CCc1c(C)nc2n(c1=O)CC(C(=O)N(C(C)C)C(C)C)CS2 +N#CCSc1nc(-c2ccco2)nc2ccccc12 +Cc1nonc1CC(=O)N1CCC(CNC(=O)c2ccco2)C(O)C1 +Cn1nc(C(=O)NCCn2ccc3ccc(F)cc32)c2ccccc21 +COc1cccc(CC(=O)N2CCN(Cc3nc(C)c(C)o3)CC2)c1 +Cc1ccccc1-c1c(C#N)nnn1-c1ccccc1 +CN(C)C(=O)Cn1cnc(NC(=O)CC2OCCc3ccsc32)n1 +CC(=O)N1CCC(S(=O)(=O)c2ccccc2)C1 +Cc1ccnc(N2CCCC(C(=O)NCCC3=CCCCC3)C2)n1 +CN(Cc1ccc(Cl)cc1)C(=O)C1CCN(C(=O)C2CC2)CC1 +COc1cc(C)c(C(C)NC(=O)c2ccc(C#N)cc2)cc1OC +O=S(=O)(c1cc(F)cc(F)c1)N1CCCC1c1ccccc1 +O=c1[nH]c(=O)n(-c2ncnc3c2cnn3-c2ccccc2)cc1Cl +CCc1cccc(NC(=O)c2cc(S(C)(=O)=O)ccc2Cl)c1 +Cc1nn(C)c(C)c1C(=O)NCCc1cc(F)cc2c1OCOC2 +CN(Cc1cc(-c2ccncc2)no1)C(=O)C1COc2ccccc2C1 +CSc1nccn1-c1cccc(C(=O)NCc2csc(=O)[nH]2)c1 +O=C(CCc1cscn1)NC1(c2ccc(Cl)cc2)CC1 +COc1ccc(C(C)(C)C)cc1C(O)CCN1CCOCC1 +CCN(C(=O)NC1CCN(S(=O)(=O)C2CC2)CC1)C1CCCC1 +CCOc1ccc(NC(=O)c2cc(C)oc2C)cc1CO +COc1ccc(C(=O)C(C)Sc2ncc(C#N)c(N)n2)cc1OC +Cn1c(=NC(=O)C2CC2)sc2cc3c(cc21)OCCO3 +COCCOc1cc(NCc2ccc3c(c2)OCO3)ncn1 +COc1cccc(CN(C)C(=O)COc2cccc(C#N)c2)c1 +Cc1c(-c2ccc3c(c2)OCO3)oc2ccc(C(O)C(C)O)cc12 +CCN(C(=O)CSc1n[nH]c(N)n1)c1cccc2ccccc12 +COc1ccccc1-n1nnnc1SCC(=O)NC(C)(C)C +O=C1NCCCCC1NC(=O)N(Cc1ccccn1)C1CC1 +COc1ccc(-c2nc(C(=O)NCCc3ccccn3)cs2)cc1 +CCc1nnnn1-c1ccccc1NC(=O)c1cnc(C)cn1 +CCn1cc(C(=O)NCc2ccc3ccccc3c2)cn1 +CC(=O)c1cccc(OCc2cc(=O)n(C)c(=O)n2C)c1 +C=CCNC(=O)CSc1nc(-c2cc(Cl)ccc2OC)n[nH]1 +O=C(NCCc1csc(-n2cccn2)n1)NCc1ccccc1 +CC(C)N(Cc1ccccc1)C(=O)c1cn(CC(=O)N(C)C)nn1 +Cc1ccc(NC(=O)CN(C)C(=O)C(C)Sc2ccccn2)nc1 +Cc1ccc(-c2noc(CSc3ncn[nH]3)n2)cc1F +CCCC(=O)NCC(=O)N(C)C(C)c1ccncc1 +CC(C)c1nc(Cn2c(C(F)(F)F)nc3ccccc32)no1 +COc1cc(NC(=O)c2cc3ccccc3[nH]2)ccc1N1CCCC1=O +COc1cc(C(=O)Nc2ccc3[nH]c(C)cc(=O)c3c2)ccc1C +CCC(CC)NC(=O)NCc1ccc(COC)cc1 +CC(C)c1noc(CCNC(=O)Nc2ccc(F)cc2)n1 +Cc1occc1C(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +CNc1cccc(C(=O)NC(C)Cn2ccnc2)n1 +COc1cc2c(cc1O)OC(c1ccccc1)C(O)C2=O +O=C(NCCC1=CCCCC1)C1COc2ccccc2O1 +O=C(Nc1cccnc1)c1ccc(OCC2CCCO2)cc1 +N#Cc1c[nH]c(C(=O)NCC(CO)Cc2ccccc2F)c1 +Cc1cccc(OCCC(=O)N2CCN(C)CC2)c1 +FC1(F)CCN(C2CCOCC2)CC12CCN(c1cnccn1)C2 +COc1ccc(OC)c(-c2cn3cccnc3n2)c1 +COC(=O)c1n[nH]cc1-c1c(C#N)c(N)nc2c1Cc1ccccc1-2 +CCC(C)(C)NC(=O)c1ccc(C)c(N(C)S(C)(=O)=O)c1 +Cc1nnc(NC(=O)CCC2CCCCC2)s1 +Cc1ccc(C(=O)N2CCC(C(=O)c3ccc(O)cc3)CC2)s1 +Cc1ccc2c(c1)N(C(=O)c1ccc(-n3ccnc3)nc1)CC(C)O2 +Cc1ccc(-c2ncco2)cc1NC(=O)NC(C)(C)c1nccs1 +CCn1nc(C)c(C(=O)Nc2cc(Br)ccc2C)c1C +COCCNC(=O)C1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +Cc1cc(NC(=O)CN(C)C(=O)CN2CCCCC2=O)no1 +Oc1cc(O)c2c(c1)C(C(O)c1ccccc1)NCC2 +Cc1ccc(NC(=O)C2(C)CC2(Cl)Cl)nc1 +CCC(C)NC(=O)Cn1cc(Br)c(=O)[nH]c1=O +CC(C)(C)OC(=O)NCC(=O)N1CCc2sccc2C1 +COc1ccc(CNC(=O)CCn2ncc3cc(OC)ccc32)cc1 +COCCN(C)C(=O)c1cn(CC#N)c2ccccc12 +CC(NC(=O)C1CC=CCC1)C(=O)NCc1ccccc1 +CCCCC(NC(N)=O)C(=O)Nc1ccc(-n2ccnc2)cc1 +CC(C)Cn1nccc1NC(=O)c1cc(C(N)=O)cs1 +Cc1cc2c(cc1NC(=O)N(C)Cc1c(C)noc1C)OCO2 +COc1ccc(C)cc1N1CC(C(=O)NC(C)C)CC1=O +Cc1cccc(C)c1OCC(=O)N(CC(N)=O)C(C)C +CCC(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2 +CCSc1nc2n(n1)C(c1cccs1)C1C(=O)CCCC1=N2 +O=C(CSc1nnc(-c2ccc(O)cc2)o1)N1CCCCCC1 +CCN(C(=O)COc1cccc(C(N)=O)c1)C1CC1 +COc1ccc2c(c1)c(OC(C)=O)cn2-c1ccc(C)cc1 +Cc1nnc(CCCn2cnn(C(C)(C)C)c2=O)o1 +CCn1c(=O)n(CC)c2cc(Br)ccc21 +CCOC(=O)c1c(NC(=O)OC)sc(C(=O)N(C)C)c1C +CC(Nc1ccc(S(N)(=O)=O)cc1)c1cccc(F)c1 +Cc1ccc(NC(=O)CSc2nnc(C)n2N)c(C)c1 +CC(C)n1cnnc1S(=O)(=O)C(C)c1ccccc1F +CCN(CC(C)C)S(=O)(=O)Cc1cccc(N)c1 +O=S(C1=CCC(Cl)(Cl)C=C1)c1ccccc1 +CC(C(=O)Nc1ccccc1)n1ncc(-c2ccccc2)nc1=O +CCc1ccc(N2Cc3nc(N4CCOCC4)ncc3C2=O)cc1 +CC1CCCC(NC(=O)CN2CCN(C(=O)CO)CC2)C1C +Cc1ccc2c(c1)CCCN2S(=O)(=O)c1ccc2[nH]c(=O)oc2c1 +Cc1noc(C)c1-c1nc(C2CCOCC2)nn1-c1cccnc1 +O=C(CCn1cncn1)Nc1nc2ccc(F)cc2s1 +O=C(NCCOc1ccccc1)NCc1ccccn1 +CC(C)Cc1cc(C(=O)Nc2ccnc3ccnn23)cc(=O)[nH]1 +c1ccc(-n2nc(CN3CCOCC3C3CC3)c3c2CCC3)cc1 +CCOc1ccccc1NC(=O)C1CC(=O)N(Cc2ccco2)C1 +[H]N=c1n(C)c2ccccc2n1CC(O)COc1ccc(Cl)cc1 +CN(C)c1nc(-c2ccccc2)c(CN2CCC3(C2)OCCO3)s1 +O=C(Cn1ncc(=O)c2ccccc21)NC1(c2ccccc2)CCCC1 +COc1ccc2c(C)c(C(=O)NCCNc3cccnc3)oc2c1 +Cn1cnnc1-c1ccc(NC(=O)Cc2cccc(OCC#N)c2)cc1 +O=C(NC1CC1)c1ccc(N2CCc3ccccc32)s1 +CC(=O)Nc1cc(NCc2cc(C)on2)ccc1F +O=C(Nc1nc(-c2cc(F)ccc2F)cs1)c1ccc(=O)[nH]n1 +Cc1ccc(S(=O)(=O)Oc2ccc(C(N)=O)cc2)cc1F +COC(=O)c1ccc(C(=O)NCc2ccccc2)cn1 +O=C(Nc1nnc(Sc2ccc3ccccc3n2)s1)C1CC1 +COc1ccc(N)cc1NC(=O)COc1ccc(Cl)c(C)c1 +COc1c(C2CCCN2C(=O)Cc2ccc(C)s2)c(C)nn1C +COc1ccc2nc(C(=O)Nc3ncccc3C)ccc2c1 +Nc1c(Br)cc(-c2csnn2)cc1Br +CCCn1ccc(NCc2cc(C(F)(F)F)nn2C)n1 +Cn1c2c(cc(C(=O)N3CCOCC3CC(N)=O)c1=O)CCCC2 +CCNC(=O)C1CCCN(C(=O)NCCCN2CCCC2=O)C1 +C=CCN(Cc1ccc(-n2cncn2)cc1)CC(F)(F)F +CCC(C)Nc1nc(-c2csc(COC)n2)cs1 +Cc1cc(C)c(NC(=O)C(C)(C)C#N)c(Cl)c1 +O=C(CNC(=O)CC12CC3CC(CC(C3)C1)C2)NCC(F)(F)F +CCOCC1CCCN(C(=O)C(C)NC(=O)c2cccc(C)c2)C1 +O=C(Cc1ccc(NC(=O)C2CC2)cc1)Oc1ccc2cn[nH]c2c1 +CCc1nnc(NC(=O)c2ccc(Oc3ccccc3OC)o2)s1 +CCNC(=O)C(C)NC(=O)NC(C)c1ccc2c(c1)OCO2 +COC(=O)c1ccc(C)c(NC(=O)CSc2ccccn2)c1 +c1cn2c(CN3CCC4(C3)OCCO4)cnc2cn1 +N#Cc1cccc(NC(=O)CCNC(=O)C2CCCC2)c1 +CCn1c(SCc2cc(F)cc3cccnc23)nc2ccccc21 +Cc1nnc(NC(=O)C2CCN(c3ccccc3F)CC2)s1 +CC(C)N(CC1CC1)C(=O)c1ccc(Br)c(N)c1 +COc1cc2c(cc1NC(=O)c1ccon1)oc1ccccc12 +Cc1cc(NC(=O)CN2CCN(C(=O)c3ccccc3)CC2)no1 +Cc1c(CNC(=O)Nc2ccc(C(C)(C)C)nn2)cnn1C +COc1cccc(C(=O)NCCNC(=O)c2ccccc2Cl)c1O +COc1cc(C(=O)N(C)Cc2ccc(O)cc2)ccc1C +Cc1cc(CNC(=O)C2CCC(=O)N(C3CCCCCC3)C2)n[nH]1 +CCCC(=O)NCC(=O)NC(C)c1ccccc1C(F)(F)F +O=C(CCCc1nc2ccccc2s1)Nc1nncs1 +Cc1sc(=O)n(CC(=O)NCC(c2ccccc2)C(C)C)c1C +COc1ccccc1NS(=O)(=O)c1csc(C(N)=O)c1 +O=C(CNC(=O)c1ccc2[nH]cnc2c1)OCc1ccccc1 +Cc1nc2n(n1)CCN(C(=O)c1cc(-c3cccnc3)[nH]n1)C2 +COCCn1nc(C)c(CNc2cnc3ccccc3n2)c1C +CCC(NC(=O)CCC(=O)c1ccc(C)s1)c1ccc(C)cc1 +CCOC(=O)CN(C(C)C)S(=O)(=O)c1ccc(C)c(F)c1 +Cc1ccc(OCC(=O)NCC#Cc2ccccc2F)cc1 +Cc1cc(C(=O)N2CCN(C(=O)C(C)C)CC2)c2ccccc2n1 +CC(C)C(NC(=O)N(C)Cc1ccccn1)c1ccccc1 +Cc1nc2cc(NC(=O)Nc3cn[nH]c3)ccc2[nH]1 +CC12CCC(C(=O)N(CCC#N)Cc3ccccc3)(OC1=O)C2(C)C +Cc1nn(C)cc1C(=O)NC(C)Cc1c(Cl)cccc1Cl +COC(=O)Nc1ccc(CNC(=O)C2CCOC2)cc1 +Cc1nnc(NC(=O)CCCn2cnc3ccccc3c2=O)s1 +Cc1csc(COc2ccc(-n3cccn3)cc2)n1 +COc1cc(C)c(NC(=O)c2cccc(N(C)C)c2)cc1OC +Cn1cc(S(=O)(=O)Oc2ccc3c(c2)CCC(=O)N3)cn1 +CC(=O)Nc1ccc(C(=O)N2CCC(Oc3ccccn3)CC2)cc1 +N#CCCCOc1cccc(NC(=O)CN2CCCCCC2=O)c1 +COc1ccc(-n2ccnc2-c2ccc(-c3cc[nH]n3)o2)c(OC)n1 +CC(C)N(C)C(=O)CNc1cccc2c1CCCC2 +O=C(Cc1ccc(F)cc1F)NCc1nc2ccccc2s1 +Cn1c(-c2ccccn2)nn(CCNC(=O)C2CC2)c1=O +COC(=O)CCCN(C)C(=O)c1cc(-c2ccc(F)cc2)c(C)s1 +O=C(COc1ccc2c(c1)OCO2)N1CCCC1c1cccs1 +CNC(=O)COc1ccc(OC(=O)C2CC=CC2)cc1 +CC(C)(C)CC(=O)Nc1ccccc1C(=O)NC1CC1 +CC(=O)N1CCc2cc(CNC(=O)C(C)C)ccc21 +Cn1cnc(CNC(=O)c2ccccc2C(C)(C)C)n1 +Cc1ccc(NC(=O)COc2c(C)[nH]ccc2=O)nc1 +Cc1cc(C)c(CNC(=O)Cn2nc(C)c(Cl)c2C)c(=O)[nH]1 +CCOC(=O)c1ccoc1COC(=O)c1cn(C)c2ccccc12 +CC1CCCN(C(=O)Cn2nnn(-c3cccs3)c2=O)C1 +COC(=O)C1CC(O)CN1Cc1cnc2c(C)cccn12 +COCCS(=O)(=O)N1CCCC1CC(=O)c1cnn(C)c1 +Cn1cc(C(=O)Nc2cccc(F)c2)c(-c2ccc(F)cc2F)n1 +O=C(c1nc2ncccn2n1)N1CCN(c2cccc(Cl)c2)CC1 +CC(=O)NCc1ccc(S(=O)(=O)NCC2CC=CCC2)s1 +O=C(NCCc1nc(-c2ccc(F)cc2)no1)C1CCC1 +Cc1ccc(OCC(=O)NCc2ccccc2)cn1 +COCC(C)NC(=O)Nc1ccc(Oc2ccncc2)cc1 +CS(=O)(=O)NC1CCN(C(=O)c2ccsc2)CC1 +CC(=O)NCCCNC(=O)NC1CCCC(C)C1 +COC(=O)CCSc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +O=C(Nc1cccnc1)C1CCCc2c1[nH]c1ccccc21 +Cc1csc(N2CCN(Cc3ccccn3)CC2)n1 +COc1cccc2c1OCC(NC(=O)Nc1ccnn1C(C)C)C2 +CC(C)C(NC(=O)c1ccccc1)n1nnc2ccccc21 +COc1cccc(-c2cc(C(=O)NCc3nnc4n3CCC4)[nH]n2)c1 +COc1cccc(CNS(=O)(=O)N2CCCCCC2)c1 +COc1ccc(CCC(=O)NCc2cc(C)on2)cc1 +O=C(NCc1cc(Cl)ccn1)Nc1cccc(Cl)c1F +CCc1cc(C(C)NCc2c[nH]nc2-c2ccc(F)cc2)on1 +COCC(=O)N1CCc2ccc(C(O)COC)cc2C1 +CC(C)CC(C#N)NS(=O)(=O)Cc1ccc(F)cc1 +C=CCn1c(C)nnc1SCCC(=O)Nc1ccc(C)cc1 +Cc1cccc(CN2CCN(C(=O)c3cc(F)ccc3F)CC2)c1 +Cc1nnnn1-c1ccc(NS(=O)(=O)NCc2ccccc2)cc1 +CC1c2cccn2CCN1c1nc(N)nc2[nH]ncc12 +CCn1nc(C)c2nnn(CC(=O)c3ccc(F)cc3)c(=O)c21 +COCCOC(=O)Cc1nc2ccc(C(C)C)cc2c(=O)[nH]1 +C=CCNC(=O)c1ccc(NC(=O)C2CCCCN2C(=O)CC)cc1 +CC(C)(C)c1nc(CC(=O)NCc2ccc3c(c2)OCCO3)cs1 +O=C(NCCc1nc2ccccc2s1)c1cc(-n2cccn2)ccn1 +c1nc(N2CCCC2c2ccc3c(c2)OCO3)c2nc[nH]c2n1 +O=C(c1cc[nH]c(=O)c1)N(CCCO)Cc1cccc(Cl)c1 +COc1ccc(C(=O)NCCS(N)(=O)=O)cc1-c1ccccc1 +O=C(CCc1ccccc1)Nc1ccnn1C1CCCC1 +NC(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)CCC3)c1 +CCOc1ccc(C(=O)N(CCc2cccs2)C2CC2)cc1 +O=C(NCC1CCOC1)c1ccc(OC2CCCC2)nc1 +COc1ccc(C(NC(=O)CCC2CCC2)C2CCOCC2)cc1 +COc1cc(O)ccc1CNc1ncccc1CO +CC(=O)N1CCNC(C(=O)N2CCC(c3nc(C)cc(=O)[nH]3)CC2)C1 +COCc1cccc(C(=O)N(C)Cc2ccc(C(=O)OC)cc2)c1 +CC(=O)Nc1cccc(OC(=O)C23CC4CC(CC(C4)C2)C3)c1 +Cc1csc(N(C(=O)c2ccc(-n3cncn3)c(F)c2)C2CC2)n1 +Cc1cc(C)c(SC(C)C(=O)N2CCNCC2)c(C)c1 +Cc1cc(C)n(C2CN(Cc3nnnn3-c3ccccc3)C2)n1 +C#CCOCC1CCCN(C(=O)c2cnc3ccccc3n2)C1 +CCN(CC(=O)N1CCCC1c1ccncc1)c1ccccc1 +O=C1CSc2ccc(C(=O)NCC(=O)NC3CCCCC3)nc2N1 +CC(C)c1ccccc1NC(=O)Cn1nc(-c2ccco2)oc1=O +CC(C)CN(C1CC1)S(=O)(=O)Cc1ccon1 +O=C(CCCOc1cccc(F)c1)Nc1ccccc1O +CC1CC(c2ccc(F)cc2)CN1C(=O)Cc1cn2ccsc2n1 +CCOC(=O)CN(CC(F)(F)F)C(=O)c1cc(C)cc(C)c1 +COc1ccc(NC(=O)c2c(C)nn(C)c2C)cc1 +Nc1cccc(-c2nc(-c3c(F)cccc3F)no2)c1 +CCCCNC(=O)CNC(=O)c1ccc(C(F)(F)F)cc1 +COc1ccc(C)cc1NCC(=O)Nc1ccc(Cl)cn1 +COc1cccc(NC(=O)N(C)Cc2ccc(F)cc2)c1 +O=C(Cn1c2c(sc1=O)CCCC2)NCC1CCCCC1 +CCOC(=O)c1noc2ncnc(N(CC)c3ccccc3)c12 +O=C1CN(C(=O)c2ccc3c(c2)OCCCO3)CCN1 +C=CCNC(=O)c1csc(Nc2ccc(OC)cc2OC)n1 +NC(=O)Cc1c[nH]c2c(OCc3ccccc3)cccc12 +CCCN(CCC)C(=O)COc1ccc(C#N)cc1Cl +CC(=O)Nc1ccc2c(c1)Cc1cc(N(CCO)CCO)ccc1-2 +COc1ccc(F)cc1NC(=O)CCOCC(F)(F)F +Cc1nn(C)cc1CNC(=O)Nc1cccc(C(F)(F)F)c1 +Cc1ccc(S(=O)(=O)N2CCCC2CC(=O)c2cnn(C)c2)cc1 +COC(=O)CS(=O)(=O)NC(C)c1ccc(N)cc1 +CC(=O)c1ccc(S(=O)(=O)NCC#Cc2cccc(Cl)c2)cc1 +Cc1cc(C)n(C(=O)c2nc3ccccc3nc2-n2nc(C)cc2C)n1 +O=C(NCCCn1cncn1)c1sc2cccc(F)c2c1Cl +CCOCc1ccccc1NCc1csc(CC)n1 +COc1nccnc1N1CCC(NC(=O)C2CCN(C(C)=O)CC2)C1 +COc1cc(CNc2cnn(CC(F)(F)F)c2)c2c(c1)CC(C)O2 +COc1cc(Cl)ccc1S(=O)(=O)n1ccnc1C(C)C +Nc1ccccc1CC(=O)Nc1cccc(C(F)(F)F)c1 +CCOC(=O)CC1CCCCN1C(=O)c1cnc(SC)nc1 +CN(C)S(=O)(=O)Nc1cc2c(cc1N)OCO2 +COc1ccc(OC)c(C(O)CSc2nccn2C)c1 +COC(=O)C(NC(=O)c1ccnc(-n2cncn2)c1)C(C)C +Cc1nc(C2CCCC2)sc1-c1nc(-c2ccc(C#N)cn2)no1 +CN1C(=O)C(O)(CC(=O)c2cc(O)ccc2O)c2ccccc21 +COc1ccc(NC(=O)Cc2c(C)nc(C)[nH]c2=O)cc1F +Cc1cccc(S(=O)(=O)N(C)c2cccc(N)c2)c1 +CCS(=O)(=O)N1CCN(c2ccc(C)nn2)CC1 +COC(=O)c1ccc(C(=O)Nc2cc(F)ccc2OC)cn1 +CCOc1ccccc1NC(=O)CCNC(=O)c1ccc(Cl)cc1 +CC(=O)c1ccc(F)cc1NC(=O)C1CCOC1 +Cn1ncc2c(NCc3cc(C4CC4)[nH]n3)nc(C3CCCC3)nc21 +NC(=O)c1csc(C(=O)Nc2cc(Cl)c(N)c(Cl)c2)c1 +CC(C)N(C(=O)COc1ccc(-n2cnnn2)cc1)c1ccccc1 +Cc1ccc(C(=O)N(CCc2cccs2)C2CC2)cc1 +CC1CN(C(C)CNC(=O)c2cnccn2)CC(C)O1 +O=C(CCc1nc2ccccc2n1-c1ccccc1)N1CCC(O)CC1 +CC(C(=O)OCc1ccccc1C(N)=O)N1CCc2ccccc2C1 +CS(=O)(=O)c1ccc(NC(=O)c2ccccc2OC(F)F)cc1 +Cc1ncsc1CN1CCCCC1C(=O)N1CCOCC1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)c(C)c1O +Cc1cccc(C)c1NC(=O)CNC(=O)c1cccc(C#N)c1 +Cc1cc(C)c(S(=O)(=O)N(CCO)C(C)(C)C)c(C)c1 +Cc1ccc(-n2ccnc2)c(C(=O)N(C)Cc2csc(C)n2)c1 +O=C(Nc1ccc(F)cc1F)Nc1ccccc1C(=O)NCC1CC1 +CCC(C)NC(=O)CCNC(=O)Nc1cc(F)ccc1OC +CN(C)C(=O)c1cccc(NC(=O)c2cc(Cl)ccn2)c1 +O=C(CNC(=O)c1cnccn1)Nc1ccc(Br)cc1 +CCC(CC)C(=O)Oc1cccc(-n2cnnn2)c1 +O=C(Cn1c(=O)cnc2ccccc21)OCCNc1ncccn1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)N1CCC2(CCOC2)C1 +CC(C)(C)Oc1cc(CNC(=O)NC2C=CCCC2)ccn1 +CCc1noc(CC)c1CC(=O)Oc1ccccc1C +Cc1nnc(Oc2cncc(Br)c2)c(C#N)c1C +O=C(Cn1c(=O)cnc2ccccc21)NCc1ccco1 +O=C(Nc1nnc2ccccn12)c1csc(Cc2ccccc2)n1 +Cc1nc2c(c(N(C)Cc3cnn(C)c3C)n1)Cc1ccccc1OC2 +Cc1cccc(CN(C(=O)CN(C)C(=O)c2ccccc2)C2CC2)c1 +COc1ccc2c(c1)CN(C(C)c1nc(C(C)C)no1)CC2 +O=C(CCCNC(=O)C1CC1)NC1CCN(C(=O)c2ccoc2)CC1 +OC1(CN2CCOC(Cn3cncn3)C2)CCCCC1 +COc1ccc(S(=O)(=O)NC(C2CC2)C2CC2)cc1F +CCOC(C)c1noc(CNC(=O)NC2(C)Cc3ccccc3C2)n1 +CCc1nc(CN2c3cccc4cccc(c34)S2(=O)=O)cs1 +O=C(NCc1ncc[nH]1)Nc1ccc(F)cc1OCC(F)(F)F +C=CCN(CC=C)C(=O)CN1CCOC(C)(C)C1 +CCc1onc(C)c1NC(=O)NCC(CC)CCO +CC(C)S(=O)c1ccc(C(=O)NCc2cccc(N(C)C)c2)cc1 +CC1CC(C)CN(C(=O)NCCCOCC2CCCO2)C1 +COc1ccc(NC(=O)c2coc(C)n2)cc1Cl +Cc1[nH]c2ccnn2c(=O)c1Cc1ccccc1F +CCC(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +COC(=O)C(NC(=O)CNC(=O)c1cc2ccccn2n1)C(C)C +O=C(NCC1CCOCC1)C1CC2C(CCN2Cc2ccccn2)O1 +COCc1nc(C)c(C(=O)N2CCCc3cc(C)cc(C)c32)s1 +NS(=O)(=O)N1CCN(C(=O)c2ccc(C(F)(F)F)nc2)CC1 +O=C(CCC1CCCO1)Nc1cc(Cl)ccc1F +Cc1ccc(-c2nnn(CC(=O)NCC3CCCO3)n2)cc1 +NS(=O)(=O)c1ccc(CCNC(=O)CCc2cccs2)cc1 +O=C(NCc1cccc(F)c1)c1cnc2ccsc2c1 +N#Cc1ccc(N2CCN(C(=O)CCc3ccc(F)cc3)CC2)nc1 +O=C1CCC(NS(=O)(=O)Cc2cccc(C(F)(F)F)c2)CN1 +Cc1cc(=O)[nH]c(SCc2cn3cc(Cl)ccc3n2)n1 +CCOC(=O)c1cncc(N(C)CCc2ccncc2)c1 +N#Cc1ccc2ccn(CC(=O)NC3CCCC3)c2c1 +Cc1cccc(C)c1NC(=O)Cn1ccc(-c2ccc(F)cc2)n1 +CCOC(=O)N1CCN(CC(=O)c2c(C)[nH]c3ccccc23)CC1 +O=C(NCC(=O)N1CCCc2ccccc21)c1cccnc1 +CCCN(Cc1ccc(C#N)cc1)S(=O)(=O)c1ccc(C)s1 +Cc1cccc(C(=O)OCC(=O)Nc2ccccc2C#N)c1N +CCOCCN(CC)C(=O)Nc1cc(Cl)ccc1N(C)C +CC(C)Cc1ccc(S(=O)(=O)N2CC(C)OC(C)C2)cc1 +CCNC(=O)c1ccc(OCc2cscn2)cc1 +Cc1ccc(C2C(C(=O)N3CCCC3)CCC(=O)N2C)cc1 +O=C(Cc1ccc(NC(=O)c2ccccn2)cc1)NC1CC1 +CCNC(=O)CCCC(O)c1c(C)c(C)cc(C)c1C +CC1Oc2ccccc2N(CC(=O)N(C)C2CC2)C1=O +Cc1ccc(-n2nnc(C(N)=O)c2C)cc1Br +COC(=O)c1cc(N)c(OC)c(Br)c1 +CCCCC(=O)Nc1c(C)nc(N2CCCC2)nc1C +Cc1ccc(C)c(OCC(=O)N2CCN(Cc3cc(C)on3)CC2)c1 +Cc1ccc(N2CCC3(CC2)CC(Oc2ccccc2)CO3)nn1 +Cc1cc(C)n(C(C)CC(=O)Nc2cccc(C(F)(F)F)c2)n1 +O=C(OCc1nncn1C1CC1)c1ccc(-c2ccccc2Cl)o1 +COCCOc1ccccc1C(=O)Nc1ccc2cn[nH]c2c1 +CC(=O)Nc1nc(C(=O)OCc2nccs2)cs1 +CCN(CC)C(=O)c1ccc(NC(=O)c2cnn(CC)c2)cc1Cl +Cc1ccccc1NCC(=O)Nc1ccc(Cl)cn1 +CCC(C)Nc1nc(-c2cccn(C)c2=O)cs1 +CCN(Cc1cn(C)nc1-c1cccnc1)Cc1c(F)cccc1F +CN(Cc1ccc(F)c(C(F)(F)F)c1)Cc1cccn1C +NC(=O)CNC(=O)CC12CC3CC(CC(C3)C1)C2 +O=C(CNC(=O)c1cc2ccccn2n1)NCCc1ccc(F)cc1 +CC(=O)c1c(C)[nH]c(C(=O)Cn2cnc(C#N)n2)c1C +Cc1ccccc1NC(=O)COC(=O)c1cccc(N(C)C)c1 +N#Cc1cccc(CNC(=O)NCCCN2CCCCCC2=O)c1 +O=C(c1ccccn1)N1CCN(c2ccccc2)CC1 +O=C(Nc1cccc(F)c1)Nc1cnn(Cc2ccncc2)c1 +CC(=O)c1ccccc1NC(=O)c1ccn(C)c(=O)c1 +CN(CC(O)C1CC1)C(=O)c1cc(C2CC2)nc2ccc(F)cc12 +CC(=O)c1ccc(NC(=O)c2cc(C)no2)cc1C +Cc1cc(C(=O)NCc2ccc(NC(N)=O)cc2)c(C)s1 +CC(=O)N1CCCN(C(=O)c2ccc(-c3nc(C)no3)cc2)CC1 +CC(=O)Nc1cc(NC(=O)COc2ccccc2)ccc1C +CCCc1cc(N2CCc3nn(CC)c(=O)cc3C2)n2ncnc2n1 +CCc1nc2ccccc2n1CC(=O)NC1CCCC1 +COc1ccc(C(=O)CNC(=O)c2ccc3c(c2)OCO3)cc1 +CC(O)CNC(=O)c1cccc(OCc2ccccc2C#N)c1 +Cc1ccc(CNC(=O)c2cn3c4c(cccc4c2=O)CC3C)cc1 +CC(C)Oc1ccccc1C(=O)NCc1ncn(C)n1 +Cc1ccc(C)c(S(=O)(=O)N(Cc2ccco2)CC2CCCO2)c1 +CCc1ccc(C(=O)N2CCN(c3nccs3)CC2)o1 +CCCOc1ccccc1OCC(=O)NC1(C#N)CCCCC1 +COc1ccccc1C(=O)Nc1ccc(-n2ccc(C)n2)cc1 +CC(C)(C)C(=O)N1CCN(CCn2c(=O)oc3cccnc32)CC1 +CNC(=O)NC(C)(C)C(=O)NCc1ccnc(OC)c1 +Cc1nc2ccc(NC(=O)CCC(=O)Nc3nccs3)cc2o1 +CC(C)(Oc1ccc(F)cc1)C(=O)NCC(N)=O +CCC(C)NC(=O)c1ccc(CNC(=O)c2cc(F)ccc2F)cc1 +COc1ccc(C2(C(=O)NCCc3ccccn3)CCCC2)cc1 +Cc1ccc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)cc1 +CC(=O)c1cccc(S(=O)(=O)Nc2ccccc2O)c1 +COc1ccc(CNc2ncnc(Nc3ccccc3F)c2N)cc1 +CCCn1c(SCC(=O)NC2CC2)nnc1-c1ccccn1 +N#Cc1ccc(N2CCC3(CC2)COCCN3Cc2cccnc2)cc1 +COc1cccc(NC(=O)NCc2nn(C)c3c2COCC3)c1OC +COc1ccc(C(NC(=O)Nc2nc(C)c(C)o2)C2CC2)cc1 +COc1ccccc1C(=O)Nc1noc(-c2ccccc2)n1 +CC(C)(O)c1cnn(-c2ccccc2)c1C(F)(F)F +COc1cc(F)ccc1N1CCN(Cc2cnc3ncccn23)CC1 +CCCc1nnc2sc(-c3c(C)nc4ccccn34)nn12 +COC(=O)c1sccc1S(=O)(=O)N=c1[nH]c(C)cs1 +CC(C)Cn1cc[nH]c1=NC(=O)c1ccc(-c2cnco2)cc1 +C#CCN1CCN(CC(=O)NCCCN2CCCCCC2=O)CC1 +C=CCN1C(=O)C2(CC(O)=Nc3[nH]ncc32)c2cccc(C)c21 +CCOc1ccc(CN(C)C(=O)c2ccc(OC)cc2OC)cc1 +OCCNc1cc(-c2ccc3c(c2)OCO3)c2cc[nH]c2n1 +CCOc1ccc(C2CCCN2C(=O)Cc2ccc[nH]2)cc1 +O=C(Cc1ccc[nH]1)NC1CCN(c2ccccc2)C1=O +Cn1c(=O)ccn(CC(=O)N2CCN(c3ncccn3)CC2)c1=O +Cc1ccc(C(=O)NCCc2c[nH]c3ccccc23)c(=O)[nH]1 +COc1cccc(C(C)NCCc2ccsc2)c1 +CNC(=O)c1cccc(NC(=O)COc2ccccc2OC)c1 +O=C(Nc1cccc(S(=O)(=O)NCc2ccco2)c1)C1CC1 +CCNC(=O)c1ccc(Cl)c(S(=O)(=O)N2CCN(C)CC2)c1 +Cc1cccc(-n2ncc(C(=O)N3CCn4c(C)nnc4C3)c2C)c1 +Cc1nc2ccc(-c3nc4ccccc4nc3C#N)cc2o1 +COc1ccc(S(=O)(=O)NCc2cc(C)oc2C)cc1OC +O=C(c1nc(-c2cccs2)no1)N1CCOCC1 +Cc1nc(C)n(CC2CN(Cc3cn4ccsc4n3)CCO2)n1 +c1cc(CNc2ccc3nnnn3n2)cc(-n2cccn2)c1 +CC1Oc2cc(N)ccc2N(CC(O)CO)C1=O +CCOc1ccccc1CNC(=O)C1CCC(=O)N1 +COc1ccc(F)cc1NC(=O)c1ccc(OC(C)C)nc1 +COc1ccc(N2CCN(CC(=O)NCCO)C2=O)cc1OC +NC(=O)C1(c2nc(-c3ccncc3)nn2CC2CCCCC2)CC1 +CC1c2cccn2CCN1C(=O)NCCc1ccn(-c2ccccc2)n1 +CC(NC(=O)N1CCCC1c1ccsc1)c1nncn1C +COc1ccc(OCC(=O)Nc2nnc(-c3cc(C)nn3C)o2)cc1 +Cc1csc(CNC(=O)NCC(O)c2ccc(F)cc2F)n1 +CN(C)S(=O)(=O)NCC(O)c1cc(F)ccc1F +CC(NC(N)=O)C(=O)N1CCCC1C1CCCC1 +O=C(CSc1ncn[nH]1)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cc1ccc(O)c(-c2cc(NCc3cccnc3)nc3[nH]ccc23)c1 +COCCc1noc(COC2CCN(C(=O)c3ccoc3)CC2)n1 +CCn1c(C)nnc1COc1ccc2c(c1)OC(C)(C)CC2=O +CCOC(=O)CCC(C)NC(=O)c1cc2c(F)cccc2[nH]1 +CCCCCNS(=O)(=O)c1ccc(NC)nc1 +OCCCn1c(CCc2ccccc2)nc2ccccc21 +Cc1nnc2ccc(N3CCCC(C(=O)NC4CCCCC4)C3)nn12 +CN(C(=O)c1cccc(N2CCOC2=O)c1)c1cccc2ncccc12 +O=C1c2ccccc2CS(=O)(=O)N1Cc1cccc(Cl)c1 +O=C(NC1CCCC1)N1CCN(C(=O)C2CCCCC2)CC1 +CCCOc1ccccc1NC(=O)c1ccc2c(c1)nnn2CC +O=C(c1cnn(C2CCCCC2)c1)N1CCCC(n2cncn2)C1 +CN(Cc1ccccc1Cl)C(=O)c1cnccc1C(F)(F)F +Cc1cc(NC(=O)c2ccc(=O)n(C)c2)ccc1OCC(F)(F)F +O=C(NCc1nc(-c2ccncc2)cs1)C1CC=CC1 +CC(=O)Nc1ncccc1NC(=O)c1ccc(Cl)cc1 +N#CC1(CN2CCN(c3ccccc3)CC2)CCCC1 +CC1CCCCC1N(C)S(=O)(=O)c1ccc(C#N)cc1 +CC(=O)Nc1nonc1-n1nnc(C(C)=O)c1C +CCS(=O)(=O)N1CCC(C(=O)Oc2ccccc2Cl)CC1 +Cc1ccc(C(=O)N=c2[nH]ccn2Cc2ccccc2Cl)c(=O)[nH]1 +Cn1c(C(=O)NCCn2cc(Cl)cn2)cc2c(Cl)cccc21 +O=C(CCCc1nc2ccccc2s1)NCc1ccccc1 +CC(C#N)NC(=O)c1cc(F)cc(Br)c1 +Cc1noc(COCC(=O)NCC2CN3CCCCC3CO2)n1 +COc1ccc(C(C)NC(=O)N2CCC(CO)CC2)cc1F +COc1ccccc1N1CCN(C(=O)c2ccoc2C)CC1 +Cc1ccccc1CNC(=O)NCC(=O)N1CCCCC1 +O=C(c1cccs1)N1CCCC(OCc2cccc(F)c2F)C1 +CCn1c(SCC(=O)Nc2ccon2)nc2ccsc2c1=O +COC(=O)C1CCN(C(=O)c2cc(-c3cccc(Cl)c3)[nH]n2)CC1 +Cc1cccc(N2CCN(CC(=O)c3cccc(N)c3)CC2)c1 +Cc1n[nH]c(C)c1SCC(=O)NCc1ccc2c(c1)OCO2 +O=C(CO)Nc1ccccc1NCc1ccc(Cl)cc1 +Cc1ccc(C)c(NC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)c1 +CCC(C)C(NC(N)=O)C(=O)NCc1ccc(C)cc1C +Cc1ccc(S(=O)(=O)Nc2nncs2)c(C)c1 +CCCNC(=O)c1ccc(-c2ccc(C(N)=O)cc2)o1 +CCNC(=O)COc1cccc(NC(=O)NC(C)C)c1 +CN(CC(=O)Nc1ccc(Oc2ccccc2C#N)cc1)C(N)=O +CCNC(=O)Nc1ccc(N2CCCC2=O)c(OC)c1 +COc1ccc(Cl)cc1N(C)C(=O)c1ccccc1N +CC(O)CNS(=O)(=O)c1ccc2c(c1)CC(=O)N2 +c1ccc2[nH]c(-c3nccn3CCn3ccnc3)nc2c1 +Oc1cccc(C2CN(Cc3ccccc3-n3cccn3)CCO2)c1 +Cc1noc(C)c1CCC(=O)NCc1ccc(OC(F)F)cc1 +COc1ccc(CN(C)C(=O)c2ccc(C(C)=O)cc2)cc1 +N#Cc1ccccc1OCC(=O)Nn1cnc2ccccc21 +CN(Cc1cc(=O)n2cc(Cl)ccc2n1)c1ccccc1 +CC(C)Oc1ncc(C(=O)N2CCN(C)CC2C)cc1Cl +COCc1nc(C(=O)Nc2ccc(N(C)C)cn2)cs1 +COC(=O)CCc1cc(OC)c(OC)cc1Br +Cc1c(C(=O)Nc2ccc(Oc3cccnc3)nc2)cnn1C +COc1ccc(NC(=O)NC2CCCc3cn[nH]c32)cc1 +COCc1ccccc1NC(=O)NCCN1c2ccccc2CC1C +COc1ccc(Cl)cc1S(=O)(=O)n1c(C)nc2ccccc21 +CC1(C)CN(C(=O)CCN2CCOCC2)CC1c1ccccc1 +O=C(Nc1nc(-c2ccccc2)cs1)c1ccc2c(c1)OCO2 +CC(C)C(=O)NCCNC(=O)Nc1cccc(SC(F)F)c1 +CCOC(=O)C1=C(C)NC(=O)C(C#N)C1c1ccc(Cl)cc1 +NC(=O)CSc1nc2ccccc2c(=O)n1-c1cccnc1 +CCc1nc2ccc(NC(=O)c3ccnn3C(C)C)cc2[nH]1 +COCC(O)CN(C)C(=O)c1cc(Cl)ccc1N +Nc1cc(F)cc2c(NCc3ccncc3)nccc12 +Cc1nocc1C(=O)N1CCC2C1CC(=O)N2c1cccnc1 +COc1cc2c(cc1OC)CN(C(=O)NCc1ccoc1)CC2 +CCN(CCO)Cc1c(O)c(=O)cc(C)n1CC +CCN(CC)C(=O)CNc1cc(S(C)(=O)=O)ccc1F +CC(NC(=O)c1cccnc1)c1ccc(C(F)(F)F)cc1 +Cc1cc(-c2ccc(C)c(S(=O)(=O)N3CCOCC3)c2)on1 +CCC(C(=O)N1CCN(c2ccccc2)C(=O)C1)N1CCOCC1 +CCCC(=O)Nc1ccc(CC(=O)N2CCOCC2)cc1 +COC(=O)c1[nH]c2ccccc2c1NC(=O)CN1CCC(=O)CC1 +Cc1ccc(C(=O)NCCCc2cn[nH]c2C)c(=O)[nH]1 +COc1ccc(-c2nc(CCNC(=O)NCC3CCOC3)co2)cc1 +CCCCCc1nnc(NC(=O)c2ccc3ccccc3n2)s1 +O=C(C1CC1c1ccc2c(c1)OCCO2)N1CCOCC1C1CC1 +O=C(NCc1ccncc1)c1cccc(-c2ccoc2)c1 +CCCNC(=O)c1ccc(NC(=O)NC(C)(CO)C2CC2)cc1 +CCn1cc(NCc2cc(OC)c(OC)c(OC)c2)cn1 +Cc1ccc(C(=O)NCC(NC(=O)c2ccc(C)nc2)C(C)C)cn1 +COc1ccccc1CCNS(=O)(=O)c1cccs1 +CCOc1cc(C(O)C(N)=O)ccc1OC(F)F +COc1ccc(-c2nnnn2C2CCCCC2)cc1N +CCOCCC(=O)N1CCC(Oc2ccc(F)cc2)CC1 +O=S(=O)(c1ccccc1)N1CCN(CC2CC=CCC2)CC1 +CCN(Cc1cccc(Cl)c1)S(=O)(=O)N(C)CCC#N +CS(=O)(=O)c1cccc(C(=O)N2CCC(O)(CO)CC2)c1 +Cc1c(N)cc(S(=O)(=O)NCC2CCC2)cc1Cl +O=C(NCCS(=O)c1ccccc1)c1ccc[nH]c1=O +Cc1ccc2ncc(C(=O)OCC(=O)N3CCCCCC3)n2c1 +CNC(=O)c1cccc(NC(=O)C(C)Nc2cccc(CO)c2)c1 +COc1cc(CNC(=O)C2CCCN(c3ncccn3)C2)ccn1 +CCN(CC)c1nc(C)cc(C(=O)N2CCOCC2)n1 +CN(CC(N)=O)C(=O)c1ccc(Br)cc1Cl +O=C(c1cc(Cl)c[nH]c1=O)N1CCCC1c1nccs1 +Clc1ccc2nc(-c3nc(-c4ccccn4)no3)cn2c1 +COCC(C)c1nc(-c2cccc(N3CCCC3=O)c2)cs1 +CCC(O)CN1CCN(C(=O)Nc2cccc(OC)c2)CC1 +CCc1nc2sc(C)c(-c3cccc(OC)c3)c2c(=O)[nH]1 +CCn1nc(NS(C)(=O)=O)c2cc3cccc(C)c3nc21 +O=C(CCc1ccccc1)NCCc1ccc2c(c1)OCO2 +Cc1ccc2nnc(C(O)c3ccc(F)cc3)n2n1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCC(O)CC2)c1 +CCc1ccc(OC)c(S(=O)(=O)NC(C)(C)C)c1 +COc1ccc(SCC(=O)NCc2ccccn2)cc1 +Oc1cccc(CN2CCC(c3ccnc(-c4cccnc4)c3)C2)c1 +CCCCNC(=O)Cn1nc(-c2ccc(Cl)cc2)ccc1=O +COc1ccc(C)c(NC(=O)c2cccc(OC)c2F)c1 +NC(c1cc(Br)ccc1CO)C(F)(F)F +Cc1cc(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)ncn1 +CC(C)(C)CCC(=O)Nc1cccc(C(=O)N2CCCCC2)c1 +CC1CCCCC1NC(=O)C1CC(=O)N(c2ccccc2Cl)C1 +Cc1nc2ccc(NC(=O)C(C)Oc3ccc(F)cc3)cc2s1 +COc1ccc(S(=O)(=O)Nc2ccccc2O)cc1N +COc1ccc(CNC(=O)NCC(O)c2ccc(Cl)cc2)cc1 +CC(=O)N1CCCc2sc(C(=O)NCC3CCCO3)nc21 +CCCn1nc(-c2cccc(OC)c2)cc(CO)c1=O +CC(=O)n1cc(C2OC(=O)C(C)C(=O)C2(C)C)c2ccccc21 +O=C1COc2ccccc2N1CCC(=O)N1CCOC2CCCCC21 +O=C(NCC#CCN1CCc2ccccc2C1)NCc1cccs1 +O=C(Nn1cnc2ccccc2c1=O)c1n[nH]c(=O)c2ccccc12 +CN1CC(C(=O)N(Cc2ccccn2)c2ccc(Cl)cc2)CC1=O +O=C(COC(=O)c1ccc2ccccc2n1)Nc1ccc(Cl)cc1 +Cc1cccc(CC(=O)N2CCN(CC(O)c3cccs3)CC2)c1 +Cc1ncccc1C(=O)N1CCC(C(N)=O)c2ccccc21 +Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)NCc1ccncc1 +CCNC(=O)N1CCOC(COc2ccc3c(c2)OCO3)C1 +CC(Oc1ccccc1C#N)C(=O)Nc1cccnc1-n1cncn1 +CC(C)C(C)NC(=O)Nc1ccc2c(c1)NC(=O)CS2 +CC(NC(=O)NC1CC2(CCC2)Oc2ccccc21)c1ccncc1 +CC(C)(C)C(=O)N1CCC(C(=O)NCc2ccc(Cl)cc2)CC1 +Cc1cc(C)c(C(=O)NCCS(=O)(=O)c2ccccc2)c(C)c1 +CNC(=O)Nc1ccc(NS(=O)(=O)c2cn[nH]c2)cc1 +C#CCOc1cc(NC(N)=O)c(Cl)cc1Cl +CCc1ccc2c(Br)cnc(N(C)CCO)c2c1 +O=C(Cn1ncc2cccn2c1=O)NCc1cccs1 +CCOC(=O)CCCC(=O)c1ccc2c(c1)OCCO2 +Cc1ccc2c(c1)N(CC(=O)NCc1ccccc1)C=NS2(=O)=O +COc1ccccc1-c1c(CO)nnn1-c1nnc(C)s1 +CCn1nccc1CNc1ccc(C(F)(F)F)nc1 +Cn1cc(Cl)cc1C(=O)N1CCCC(CO)C1 +c1cc2c(cc1CN1CCc3nncn3CC1)OCO2 +COC(=O)C1CCCCN1S(=O)(=O)c1cc(F)ccc1C +CCOc1ccc2c(c1)sc(=NC(=O)c1ccn(C)n1)n2C +C#CCN1CCC(C(=O)Nc2cccc(C)c2C)CC1 +Clc1ccccc1-c1nnc(SCc2ccncc2)o1 +O=C(CC12CC3CC(CC(C3)C1)C2)Nc1noc2ncccc12 +Cc1ncsc1C(=O)NC1CCN(c2ccc(Cl)cn2)CC1 +COC1COC2(CCN(C(=O)c3cccc(O)c3)C2)C1 +NC(=O)CCCC(O)c1ccc(C2CCCCC2)cc1 +Cc1ccc(C(C)OC(=O)Cn2cnc3c(cnn3C)c2=O)cc1 +O=C(c1ccc(F)cc1)N1CCN(CCn2cccn2)CC1 +COC(=O)c1ccc(NC(=O)c2cn(C)nc2C(F)(F)F)cc1 +CC(OC(=O)COc1ccccc1C(F)(F)F)c1ccccn1 +CC(NC(=O)Cc1ccc(F)c(F)c1)c1nc(C2CCCCC2)no1 +O=C(Nc1cccc(-c2cc[nH]n2)c1)c1ccccn1 +CCc1ccc(OCC(=O)N2CC(C)OC(C)C2)cc1 +CCC1(C)NC(N)=Nc2nc3cc(C)c(C)cc3n21 +CC(=O)Nc1ccc(F)c(C(=O)N2CCOC(C)(C)C2)c1 +Cc1ccccc1CN(C)C(=O)c1ccc(O)c(Cl)c1 +CCc1noc(CC)c1CNC(=O)N(C)Cc1ccccn1 +CC(=O)Nc1ccc(F)c(NC(=O)NCC2(C)CCCC2)c1 +COC(=O)c1cc(Br)ccc1NC(=O)c1cc(C)no1 +O=C(NCc1ccc(Cn2cncn2)cc1)c1cccs1 +CCn1c(C(N)c2cccc(OC)c2)nc2ccccc21 +COc1ccc(C(=O)NC(C#N)CC(C)C)cc1OC +Cc1csc(NC(=O)CNc2ccccc2Cl)n1 +CC(C)Oc1ncccc1CNC(=O)c1ccccc1S(C)(=O)=O +C=C(C)CN(CC)C(=O)COc1cc(C)ccc1C(N)=O +Cn1cnnc1Sc1ccc(NC(=O)c2cc3ccccc3[nH]2)cc1 +COc1ccc(NC(=O)N(CCC#N)Cc2cccnc2)cc1F +CC(NC(=O)C1CCN(C(=O)C2CC2)CC1)c1cccc(C#N)c1 +COc1ccc(CN(C)C(=O)CSc2n[nH]c(=O)n2C)cc1F +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)Nc1cccc(Cl)c1 +CCN(CC(=O)OC)C(=O)COc1cccc(F)c1 +COC(=O)N1CCC(NC(=O)CCCSc2ccccc2)CC1 +COc1cc(NC(=O)c2cnccn2)cc(OC)c1OC +CC(=O)Nc1nnc(-c2ccc3c(c2)OCO3)s1 +CN(CCC(F)(F)F)C(=O)c1cnn(Cc2ccccc2Cl)c1 +CCn1cc(C(=O)Nc2cc(C(=O)N(C)C)ccc2C)cn1 +CC(=O)N1CCN(C(=O)Cn2nc(-n3cccn3)ccc2=O)CC1 +CSc1ccc(C(=O)N(C)Cc2ccc(C)o2)cc1 +Cc1ncsc1CCC(=O)N(C)CCc1scnc1C +COc1ccccc1C(NC(=O)c1ccc(C(N)=O)nc1)C(C)(C)C +CC(Sc1nnnn1Cc1ccco1)C(=O)NCc1ccccc1 +CC(C)c1nn(C)cc1-c1nc2ccc(S(C)(=O)=O)cc2[nH]1 +COc1ccccc1CC(=O)Nc1cccc(Oc2cnccn2)c1 +COc1ccc(C(C)(CO)Cc2ccccn2)cc1 +COCC1(C(=O)N2CCNCC2C(=O)NCc2ccncc2)CCC1 +C=CCn1nnnc1SCC(=O)Nc1cc(C)ccc1C +COCC(C)NC(=O)COc1ccc(Br)cc1 +O=C(Cc1c[nH]c2ccccc12)Nc1cccc(-c2ccc(=O)[nH]n2)c1 +O=C1CCC2(CCCN(C(=O)c3cnc[nH]c3=O)C2)CN1CC1CC1 +CC1CCN(C(=O)C(C)OC(=O)c2cccc(-n3cnnn3)c2)CC1 +Nc1c(Br)c(=O)[nH]c(=O)n1Cc1cccnc1 +C#CC(C)(C)OCC(O)CN1CCN(c2ccccc2OC)CC1 +O=C(NCc1ccccc1)NCC1CCN(c2ncccn2)CC1 +Cc1nnc(SCC(=O)N(Cc2ccccc2)C(C)(C)C)s1 +CC(C)(C)n1cc(C(=O)Nc2ccc3c(c2)OCO3)c2cccnc21 +Cc1ncsc1CN1CCN(CCNC(=O)NC(C)C)CC1 +O=C(Nc1ccc2c(c1)CCC2)c1sccc1-n1cnnn1 +O=C(NCCc1ccccn1)c1cc2c(Cl)cccc2[nH]1 +Cc1oc(-c2cccs2)nc1CSc1nncn1C(C)C +Cc1ccc(CCCc2nc(-c3cnn(C)c3)no2)s1 +COc1ccc(C)cc1NC(=O)C(C)OC(=O)c1ccsc1 +Cc1ccc(NC(=O)COc2ccc3c(c2)OCO3)cc1 +Cc1ccc2[nH]cc(S(=O)(=O)c3cccc(C#N)c3)c(=O)c2c1 +Cc1oc(-c2cccc(F)c2F)nc1Cn1cc(CCO)cn1 +Cc1nn(C)c2c1C(c1ccc(C#N)cc1)CC(=O)N2 +CC(C)N(CC(=O)Nc1ccc(F)cc1)C(=O)C1CC2CCC1O2 +COc1ccccc1CN(Cc1cccnc1)C(=O)c1csnn1 +COc1ccc(NC(=O)c2csc(NC3CC3)n2)c(OC)c1 +COc1ccc(S(=O)(=O)NCc2ccccc2C)cc1C +CN(C)C(=O)N1CCN(C(=O)NCc2cccc3cccnc23)CC1 +Cc1ccc(NC(=O)CC2C(=O)Nc3nc(C)nn32)cc1 +CCc1noc(C)c1C(=O)OCC(=O)Nc1c(C)cccc1C(C)C +Brc1cnn2cc(-c3cncs3)cnc12 +Cc1nc(-c2cccs2)c(NC(=O)c2ccccc2)s1 +Cc1nnnn1-c1cccc(NC(=O)c2cc(CC(C)C)n[nH]2)c1 +CN(CC1CCCO1)C(=O)c1cccc2c1OCO2 +CCOC(=O)CCC(C)NC(=O)c1nccc2ccccc12 +C=CCN(Cc1ccccc1)Cc1cnc(N2CCOCC2)nc1 +Nc1cccc(NC(=O)CCCn2ccc(=O)cc2)c1 +CCN(CC1CCOC1)C(=O)C1CC(=O)N(c2ccc(F)cc2)C1 +CCOc1ccccc1CCc1nc(C)c(CCO)s1 +Cc1ccc(NC(=O)c2ccccc2SCC(=O)N(C)C)nc1 +Cc1cc(C)c(CNC(=O)c2cc(-c3ccccc3)no2)c(=O)[nH]1 +N#CCCCCCCC(=O)c1cnccc1Cl +CCOC(=O)c1ccc(N2CCN(C(=O)NC3CCCC3)CC2)nc1 +CCC1CN(C)c2ccccc2CN1C(=O)CCC1CC1 +CCCC(CC)NC(=O)c1cccc(F)c1NC +COc1ccc(N)cc1-c1nnc2ccc3ccccc3n12 +CCCC(C(=O)OCc1nc(N)nc(N)n1)c1ccccc1 +CC(C)c1nc2ccc(NC(=O)CCn3cncn3)cc2s1 +Cc1cccc(S(=O)(=O)Cc2ncc(-c3ccccc3)o2)c1 +C=CCNC(=O)c1cc(-c2cccc(C(F)(F)F)c2)n(CC)n1 +CCCc1cc(=O)oc2cc(OCC(=O)Nc3nccs3)ccc12 +Cc1cc(CC(C)NC(=O)c2cc(C(C)C)no2)[nH]n1 +C=CCN(C(=O)c1[nH]c(C)c(C(C)=O)c1CC)C1CC1 +O=C(COc1cccnc1)NCc1ccccc1-c1ccsc1 +CC(OC(=O)c1ccc(F)cc1)C(=O)Nc1ccc(C(N)=O)cc1 +O=C(N=c1[nH]nc2ccccn12)c1cc(F)ccc1Cl +CCc1cccc(NC(=O)C(C)N2C(=O)CCn3nc(C)cc32)c1 +COc1cccc2c1cc(C(=O)N(C)Cc1cccc(F)c1)n2C +CCCCS(=O)(=O)N1CCC(OCc2ccccc2C)CC1 +CCCn1nc(C(=O)NC(C)c2cc(F)ccc2OC)ccc1=O +CCCS(=O)(=O)N(C)Cc1ncc(-c2ccccc2)o1 +O=C(C1CC1)N1CCOC(CN2CCN(c3ccc(F)cc3)CC2)C1 +Cc1ccc(CC2CCCN(C(=O)c3ccn(C)c(=O)c3)C2)cc1 +COCCn1cncc1CNC(=O)Nc1nncs1 +C=CCNC(=O)c1nnn(-c2ccc(Cl)cc2)c1C +CCn1c(SC(C)C(=O)N(C)CCC#N)nnc1-c1ccco1 +COc1cc(CCNC(=O)c2cc(C)on2)ccc1C +COc1cccc(-c2nnc(NC(=O)c3ccccc3SC)o2)c1 +CC(=O)Nc1cccc(NC(=O)OCC(F)(F)F)c1 +CCCNC(=O)CNC(=O)CC1Sc2ccccc2NC1=O +COc1ccccc1CN(C)C(=O)COC(=O)c1cccc(O)c1 +Cc1ccc(SCCN(C)C(=O)CC2CCOCC2)cc1 +COC(=O)c1c(NC(=O)Cc2ccc(F)cc2)c(C)nn1C +c1cc(CN2CCNc3cc4c(cc32)CCCC4)ccn1 +CCN(c1cccc(C)c1)S(=O)(=O)c1c[nH]c(C(=O)OC)c1 +Cc1cc(N)nc(SC(C)C(=O)N(C)C2(C#N)CCC(C)CC2)n1 +O=C1COc2ccccc2N1CC(=O)N1CCOC2CCCCC21 +O=C(CCC1CCCO1)N1CCN(CC=Cc2ccccc2)CC1 +CCS(=O)(=O)NCCSc1nnc(-c2ccccc2)o1 +COC(=O)c1ccc(NC(=O)COc2ccccc2OC)cc1 +O=C(CCC(=O)c1ccc(F)c(F)c1)NCc1ccc(F)cc1 +COCC(O)CN(C)C(=O)c1c(C)oc(C)c1C +O=C(NC1CC1)N1CCCN(C(=O)c2cccs2)CC1 +CS(=O)c1ccccc1NC(=O)COCC(F)(F)F +Cc1ccc(CN2CCOCC2)cc1NC(=O)C1CC=CC1 +Cc1cccc(CC(=O)NC2CC(=O)N(c3ccc(Cl)cc3)C2)c1 +Cc1nc(NC(=O)CCCC(=O)N2CCNC(=O)C2)sc1C +CSc1n[nH]c(N)c1S(=O)(=O)c1ccccc1 +CC1CC1C(=O)Nc1ccc(F)cc1C(=O)NCc1ccco1 +Cc1ccc(NC(=O)N2CCN(c3ccc(C)nn3)CC2)cc1 +O=C(c1cncnc1)c1ccc(Br)cc1Cl +Cc1cccc(CN(C)C(=O)CNC(=O)c2ccc3c(c2)OCO3)n1 +O=c1c(=Cc2cccs2)sc2n1CCCN=2 +COC1CCN(S(=O)(=O)c2cc(Cl)ccc2C)CC1 +CCCNc1nc2cc(-c3nccs3)ccc2[nH]1 +COCCCNC(=O)Nc1cccc(Br)c1 +CS(=O)(=O)N1CCCC(C(=O)Nc2cc(F)ccc2F)C1 +CC(NC(=O)c1cccs1)c1ccc2c(c1)NC(=O)CO2 +CCC1COCCN1Cc1cc(OC)ccc1OC(F)F +O=C(NCC1COC2(CCCCC2)O1)C1CCCCC1 +COc1cc(C)cc(C)c1-c1cn[nH]c(=O)c1CO +CCC(=O)Nc1ccc(NC(=O)CNCc2ccccc2)cc1 +NC(=O)Nc1cccc(CS(=O)(=O)c2ccc(F)cc2F)c1 +Cc1cccc(C)c1NC(=O)COC(=O)c1n[nH]c2ccccc12 +CC(C)CNC(=O)c1cnc(-c2ccccn2)nc1N +COC(=O)CN(Cc1ccc(F)c(F)c1)Cc1csc(C)n1 +Cn1nc(C(=O)NCc2nc(Cc3ccccc3)no2)ccc1=O +COCCN(C)C(=O)NCCc1ccccc1OC +COC(=O)CCN(CC1CCCO1)C(=O)c1ccc(C#N)cc1 +Cc1ccc(C=CCC(=O)NC2C=CC(CO)C2)cc1 +Cn1ccn(Cc2cc(C#N)ccc2F)c(=O)c1=O +Cc1nc2n(n1)CCCC2NC(=O)NC1(C)Cc2ccccc2C1 +CC(C)COC(=O)N1CCC(C(=O)Oc2ccc3cn[nH]c3c2)CC1 +COc1ccc(-n2nc(C(=O)NC3CC3)c(=O)cc2OC)cc1OC +CNC(=O)C1COC(=O)N1Cc1cccc(C#N)c1 +NC(=O)CCCNC(=O)CCc1ccc(F)cc1 +CC(CNC(=O)c1ccc(OCC(F)F)nc1)c1ccsc1 +CC(C)NC(=O)c1cc(-n2cnnn2)ccc1Cl +CCC(C)OCC(=O)Nc1nc2ccc(N)cc2s1 +Cn1cc(CC(=O)NCC2CCOC2)c2ccccc21 +Cc1ccsc1-c1nnc(SCCC2OCCO2)o1 +O=C(NC1CCc2c(O)cccc21)c1ccccc1F +Cc1csc(C(C#N)C(=O)Cc2ccn(C(C)C)n2)n1 +CC(C)Cn1cc(NCc2ccccc2N2CCOCC2)cn1 +CCC(C(=O)NCc1cn(-c2ccccc2)nn1)N1CCCC1=O +CC(=O)N1CCCC(C(=O)NCc2csc(C3CC3)n2)C1 +CCC1C(=O)NCCN1C(=O)C(C)Oc1ccccc1C(F)(F)F +CN(CCc1ccc(F)cc1)C(=O)c1ccc(-n2ccnc2)nc1 +CC(=O)NC1CCCN(C(=O)Nc2cnn(-c3ccccc3F)c2)C1 +N#CCC(=O)Nc1ccc(S(=O)(=O)N2CCOCC2)cc1 +CC(N)C(=O)c1ccc(S(=O)(=O)C2CCCC2)cc1 +C=CCN1CCC2(CCN(c3ncccn3)CC2)C1=O +CCN(CC)S(=O)(=O)c1ccc(NC(=O)C2CC=CCC2)cc1 +COc1ccccc1N1CC(C(=O)Nc2cc[nH]n2)CC1=O +COc1ccc(OC)c(-n2ccc3c(c(C)nc4ncnn43)c2=O)c1 +NC(=O)C1CCN(C(=O)CSc2ccc(Cl)cc2)CC1 +COCCN1CC(C(=O)NC2CCC(C)CC2)CC1=O +Clc1ccc(-n2cc(-c3cnccn3)cn2)cc1 +CC1CC(C)CN(C(=O)c2ccc(-c3ccccc3)nc2N)C1 +COc1ncccc1CNC(=O)c1ccc(-n2ccnn2)cc1 +CC(=O)N1CCC(NC(=O)NCC(=O)NC(C)C)CC1 +CC1(C)CN(C(=O)c2ccccn2)c2ccccc2S1 +COc1ccc(OC)c(CN(C(=O)C2CC=CC2)c2cnn(C)c2)c1 +O=C(NCc1ccc(F)cc1C(F)(F)F)N1CCCC1 +CN(C)C(=O)CNC(=O)NC(c1ccccc1)c1cccc(F)c1 +CCc1nc(C2CCCN2C(=O)CCc2nc(C3CC3)no2)no1 +CC(C)(C)C(=O)N1CCN(C(=O)CN2CCOCC2)CC1 +COC(=O)NCC(=O)Nc1ccccc1-c1ccccc1 +O=C(Oc1ccc(OCC2CC2)cc1)c1cnc2n(c1=O)CCS2 +Cc1cccc(Cn2cc(NC(=O)c3cccc(C#N)c3)cn2)c1 +CN(C(=O)CN1C(=O)CSc2ccccc21)c1ccc(F)c(F)c1 +COc1ccc(-c2cc(=O)c3c(O)cc(O)cc3o2)cc1O +CC1CCCC(CO)(NC(=O)Cc2cccs2)C1 +CC(=O)c1ccc(-c2ccc3[nH]c(=O)oc3c2)s1 +COc1ccc2c(c1)OCC(C(=O)Nc1ccc(F)c(C#N)c1)C2 +CC(=O)NCc1ccc(-c2noc(CSc3ccncc3)n2)s1 +CCC(c1cccs1)n1ncc(Br)c1N +CCNC(=O)c1ccc(NCc2ccccc2-n2ccnc2)nn1 +CCOc1ccccc1C1=CCN(c2ncnc3c2cnn3C)CC1 +CCC(C)n1ncc(C(=O)NC(C)c2ccccc2)c1C1CC1 +Cc1ccc(CC(=O)Nc2cccc(OCCCC#N)c2)cn1 +CCOc1cccc(-c2cnn(CC)c(=O)c2N)c1 +Cc1ccc(S(C)(=O)=O)cc1S(=O)(=O)N(C)C1CC1 +CCC(NC(=O)Nc1ccc(C(=O)NC2CC2)cc1)c1cccs1 +CC(=O)c1sc(CCNCc2ccc(C)cc2)nc1C +O=C1COc2cc(C(=O)N3CCOCC3)ccc2N1 +O=C(NCc1nc(-c2ccc(Cl)cc2)no1)c1cccnc1 +CCC(C(=O)N1CCC2(CC1)COC(=O)O2)n1cccn1 +CN(C(=O)CN1C(=O)COc2ccc(Cl)cc21)C1CC1 +O=C(c1cc[nH]n1)N1CCN(CC(O)c2ccccc2)CC1 +COc1ccccc1OCCC(=O)N1CCOc2ccc(F)cc21 +O=C1CN(C(=O)CNc2ccccc2C(=O)N2CCCCC2)CCN1 +CCC(=O)Oc1ccc(C(=O)Nc2ccccc2)cc1 +CC(=O)NCC1CCCN(C(=O)NCc2cccc(NC(C)=O)c2)C1 +CNC(=O)c1ccc(=O)n(CC(=O)NC(C)C)c1 +Cc1cc(C)c(NC(=O)CNC(=O)c2cccn2C)c(C)c1 +CNC(=O)c1cccc(CCNc2ncccc2C#N)c1 +C=CCc1ccc(OCC(=O)NC(C)(C)C)c(OC)c1 +Cc1ccc(CCNC(=O)N2CCOC(C(N)=O)C2)c(C)c1 +O=C(c1ccccc1)C(O)C1C(=O)Nc2ccccc21 +Cc1ccn(CCCOc2ccc(S(C)(=O)=O)cc2)c(=O)c1 +CCc1cccc(CC)c1NC(=O)N(C)CC1(CO)CCOCC1 +Cc1ccc(N(C)S(=O)(=O)c2ccc(C#N)cc2)cc1 +Cn1ccnc1SCC(=O)N(CCC#N)Cc1ccco1 +C#CCN1C(=O)C(Cc2ccccc2)Oc2cc(N)ccc21 +CC(=O)Nc1ccccc1OCc1coc(-c2cccs2)n1 +O=C(Nc1nc(-c2ccc[nH]2)cs1)c1cnc(-c2ccccc2)nc1 +Cc1nc(C(=O)Nc2ccc3c(c2)OC(c2ccccc2C)N3)c[nH]1 +COc1ccc(-c2nc3ccccc3n2CCCC#N)cc1OC +O=C(CCCNC(=O)c1nc2ccccn2n1)Nc1ccc(F)cc1 +CCc1nc2n(n1)CCCC2NC(=O)c1ccnc(N(C)C)c1 +CNC(=O)NCC(=O)N(C)C(C)c1ccccc1Cl +Cc1cc(=O)[nH]c(-n2nc(C3CC3)cc2NC(=O)CC2CCCC2)n1 +O=C(CCc1cccs1)NCc1csc(C2CC2)n1 +CN(C)C(=O)N1CCC2C1CCN2c1ncccn1 +COC(=O)C(C)NC(=O)Cc1c(C)nn(CC(C)C)c1C +COc1cccc(CSc2nc3c(cc2C#N)CN(C)CC3)c1 +CCOC(=O)CNC(=O)c1ccc(Cl)cc1N1CCCC1=O +OCC(CNc1ccc2nncn2n1)Cc1ccc(F)cc1 +O=C1CN(C(=O)c2ccc(OCC3CC3)cc2)CCN1 +O=C(NC1CC(=O)N(Cc2cccc(F)c2)C1)c1ccccn1 +O=C(Nc1ccc(-c2nccs2)cc1)c1ccc(-n2ccnn2)cc1 +C#CCN1CCC(C(=O)N2CCN(C(=O)CC(F)(F)F)CC2)CC1 +CCOCCCNC(=O)Nc1cccc(SC)c1 +CNC(=O)c1cc(=O)n(CC(=O)Nc2cccc(C)c2)c2ccccc12 +O=C(Cn1nc2n(c1=O)CCCCC2)NCCO +CN(Cc1cccc(O)c1)C(=O)C(c1ccccc1)n1cccn1 +CC1CCN(C(=O)CSc2nc3sccc3c(=O)n2C)CC1 +CCOC(=O)CCCn1cnc2c(C)cccc2c1=O +CCOC(=O)N1CCCC(C(=O)OCC2CC=CCC2)C1 +Cc1nnc(N(C)CCCNC(=O)OC(C)(C)C)s1 +O=C(NC1CCCC1)C1CCCCN1S(=O)(=O)c1ccccc1 +O=C1CCC(CC(=O)N2CCc3[nH]nc(-c4ccccc4F)c3C2)N1 +CCCNC(=O)N(CCOC)Cc1ccccc1 +CC(CN1CCCC1=O)NC(=O)C1(C)CC1(Cl)Cl +CC(NS(C)(=O)=O)C(=O)NC(C)c1cc2cc(Cl)ccc2o1 +CC(c1cccs1)n1cnc2sc3c(c2c1=O)CCNC3 +O=C(CN1c2cccc3cccc(c23)S1(=O)=O)c1ccccc1 +CC1=C(C)C2=CC=CC(c3c(-c4ccccc4)ncn3CCO)C2=N1 +CC(NS(C)(=O)=O)C(=O)Nc1ccccc1C(C)C +O=C(Nc1ccc(Cl)cn1)c1cn2ccccc2n1 +O=C(NCc1ccc(-n2cncn2)nc1)c1ccoc1 +CCn1nc(C)cc1C(=O)NCCC(C)c1ccc(OC)cc1 +NC(=O)c1oc2ccccc2c1NC(=O)c1ccccn1 +CCCn1c(SCc2noc(CC(C)C)n2)n[nH]c1=O +Cc1cc(F)ccc1S(=O)(=O)NCc1ccccc1 +O=C(NC1CCc2ccc(F)cc21)c1cccnc1OCC(F)F +Cc1ccc(-c2nnc3c4ccccc4[nH]c(=O)n3c2=O)cc1 +CN(C(=O)c1cnc(-c2ccccc2)nc1N)c1ccccc1 +CC(NC(=O)c1ccnc(-n2ccnc2)c1)c1cccnc1 +CCc1ccc(N2CC(C(=O)NCCCn3ccnc3)CC2=O)cc1 +CC(O)CN1CCN(C(=O)C2CCc3ccccc32)CC1 +O=C(c1ccc[nH]1)N1CCn2cccc2C1c1ccccc1 +COc1cccc(Cl)c1CC(=O)Nc1ccc(F)c(C(N)=O)c1 +O=C1NC(CO)C(=O)N2CCN(C(=O)c3ccc(F)cc3)CC12 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NC(C)C1CCCCC1 +Cn1c(NCC(O)COc2ccccc2)c(C#N)c(=O)n(C)c1=O +CCN(CCO)c1ncnc(Nc2nc3c(C)cccc3s2)c1N +CC(NC(=O)c1ccccc1)C(=O)N(CCC#N)Cc1cccnc1 +CC(=O)c1ccc(OCC(=O)NCC2CCCCC2)cc1 +Cc1ccc(NC(=O)CSc2nc(N)cc(N)n2)cc1C +CCOC(=O)CC(C)CNC(=O)N1CCC2OCCCC2C1 +CCOc1ccc(NC(=O)N2CCC(Oc3ccccc3)CC2)cc1 +Cc1c(C(=O)N2CCCCC2C)cnn1-c1ccncc1 +COC(=O)c1ccccc1Nc1ncnc(-n2nc(C)cc2C)c1N +Cc1nn(C)c2nc(N3CCCCC3CC(N)=O)sc12 +O=C(COc1cccc(CO)c1)N1CCOCC1 +CCN(CC(=O)NCc1ccc(F)cc1)C(=O)Cc1cccs1 +CCOc1ccc(S(=O)(=O)N2CCNCC2)cc1 +Cc1ccc(S(=O)(=O)N2CC(C)OC(c3ccccc3)C2)cc1 +COC(=O)c1cc(NCc2cccnc2)ccc1C +Cc1ccc(C(=O)N(Cc2ccccn2)c2ccc(F)cc2)c(C)n1 +O=C(NCc1ccncc1)N1CC(Oc2ccccc2Cl)C1 +CC(=O)Nc1ccc(S(=O)(=O)NCc2ccccn2)cc1 +Cc1ccc2nc(COc3ccc(C(=O)NCCO)cc3)cn2c1 +C#CCOC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1OC +Cc1cc(N2CCN(C(=O)c3cccc(F)c3)CC2)c(F)cc1C#N +CC(=O)N(C)CC(=O)NC1(c2ccc(F)cc2F)CCOCC1 +Cc1ccc(C(=O)NCC(c2ccc(C)o2)N2CCOCC2)cn1 +O=C(Cn1nnn(-c2ccccc2)c1=O)N1CCCC1 +Cc1sc(=O)n(CC(=O)N2CCCc3cc(Cl)ccc32)c1C +CCOc1ccc(CC2C(=O)Nc3ccc(C)cc32)cc1OC +CC(C)NC(=O)N1CCC2(CC(Nc3cnccn3)CO2)C1 +O=C(Nc1cccc(C(F)(F)F)n1)c1ccc(F)nc1 +N#Cc1cccc(Oc2ccc(NC(=O)NCc3ccncc3)cc2)c1 +COc1ccccc1-n1cnnc1SCC(=O)N1CCC(C)CC1 +CC(CO)(NC(=O)NCCC(=O)NC1CCCC1)C1CCCCC1 +Nc1c(-c2nc(-c3ccccc3)no2)nnn1-c1ccc(Cl)cc1 +CC(C)(C)c1cc(NC(=O)Cn2c(-c3ccccc3)noc2=O)on1 +CC(C)CC1CC(O)=Nc2c1cnn2Cc1ccco1 +CCNC(=O)C(C)Sc1ncnc2sccc12 +CCNC(=O)CN(c1ccc(Cl)cc1C)S(C)(=O)=O +CCCCc1nnc(NC(=O)CSc2nc(C)n[nH]2)s1 +Cc1cc(Br)cn2cc(CC#N)nc12 +O=C(c1ccnc(OC2CCC2)c1)N1CCC2(CCC2)C1 +Cc1n[nH]c(SCC(=O)NC2(C)Cc3ccccc3C2)n1 +C#Cc1cccc(NC(=O)N2CCN(C(C)C(=O)NC3CC3)CC2)c1 +CC(C)N(CC(N)=O)C(=O)CCCc1cccs1 +COC(=O)c1ccnc(NCc2ccccc2OC)c1 +Cc1n[nH]c2oc(N)c(-c3ccc4ccccc4n3)c12 +CCc1cccc(CC)c1NC(=O)COc1ccc(C#N)cc1OC +Cc1ccc(-c2cc(=O)n(CC(=O)N3CCCC3)cn2)cc1 +Cc1noc(C)c1NC(=O)C1CCN(C(=O)c2ccco2)CC1 +Cn1c(SCC(=O)c2ccccc2)nnc1-c1cccs1 +CCCn1cc(NC(C)c2nc3ccccc3o2)cn1 +CCCCCn1c(C)cc(C)c(C(C)(C)O)c1=O +CCc1ccccc1NC(=O)c1cc(C2CC2)on1 +O=C(Cc1ccc[nH]1)NC1CC1c1ccccc1F +CCc1ncc(C(=O)N(C)Cc2cnc3ccccc3n2)cn1 +CCC(NC(=O)c1ccc(F)nc1)c1cnn(CC)c1 +N#Cc1c(-c2ccc3c(c2)OCCO3)nc2ccc(Cl)cn12 +Cc1nc(C2CCCCCN2c2ccc(C#N)cn2)no1 +CCOC(=O)c1sc(NC(=O)c2cn3ccccc3n2)cc1C +CCCCNC(=O)c1cc(C2CC2)nc2c1cnn2C(C)C +Cc1cccnc1NC(=O)c1ccc(OC(F)(F)F)cc1 +O=c1c2ccsc2ncn1CC(O)COCc1ccco1 +CC(NC(=O)N1CCC(N(C)c2ccccc2)CC1)c1cccnc1 +Cc1ccc(NC(=O)C2CC2)cc1NC(=O)Cc1cccc(O)c1 +N#Cc1c(-c2cnc3cc(O)ccc3c2)cc(C2CC2)nc1N +Cn1c(CCC(=O)N2CCOCC2CC(N)=O)nc2cccnc21 +CCc1nn2c(CNC(=O)Cc3ccccc3OC)c(C)nc2s1 +CCCC1CN(C(=O)c2ccc(=O)n(-c3ccc(F)cc3)n2)CCO1 +Cc1ccc(Cl)cc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +O=C(Cc1cc(-c2ccc3c(c2)OCCO3)on1)NCC1CCCO1 +CCCN(CCOC)C(=O)c1c[nH]nc1-c1ccccc1F +Cc1ccc(OCC(=O)N(C(C)C)C(C)C)nc1 +COc1ccc(-c2[nH]c(=O)c(C#N)cc2C)c(OC)c1 +Cc1cccc2c(=O)n(CC(=O)N(CCC#N)C(C)C)cnc12 +O=C(CCn1ccccc1=O)N(C1CCCC1)C1CC1 +CN(C)c1ccccc1C(=O)N1CCC(C(=O)N2CCCC2)CC1 +COCC(C)Nc1ncnc(Nc2nc3ccc(C)cc3s2)c1N +O=C(CNS(=O)(=O)N1CCCC1)Nc1ccc(-n2cccn2)cc1 +Cc1ccc(NC(=O)c2cc3ncccn3n2)cc1C +CCOc1ncccc1NC(=O)NC1CCN(C(C)=O)CC1 +Cc1[nH]ncc1C(=O)N(C)CC12CC3CC(CC(C3)C1)C2 +CCC(C)n1nccc1NC(=O)Cc1coc2cc(OC)ccc12 +CCCn1nnnc1CSc1cccc(Cl)c1 +O=C(CNC(=O)c1ccoc1)NCCC1CCCCC1 +CNC(=O)c1ccc(NC(=O)CN2CCCc3ccccc32)cc1 +COc1ccc(F)cc1NC(=O)NC(C)Cc1c(C)nn(C)c1C +CCCn1nc(C(=O)OCc2nnc(C)o2)c2ccccc2c1=O +Cc1ccccc1-n1ncc(C(=O)Nc2nccn(C)c2=O)c1C +CCc1ccccc1C(=O)N(C)Cc1c(C)nc2sc(C)cn12 +Cc1ccc(C(=O)CCSc2nnnn2C)cc1 +Cc1cc(C(=O)N(Cc2ccccc2)c2ccccc2)on1 +CCC(C)n1ncc(C(=O)NCc2cc(C(C)C)no2)c1C1CC1 +Cc1nc(-c2cccnc2)nc(N2CCCC(CCC(N)=O)C2)c1C +CC1COCC(C)N1C(=O)Cc1cccc2cccnc12 +CC(C)CNC(=O)c1ccc(CN2CCOCC2)c(N)c1 +CCC(CO)NC(=O)Nc1nn(-c2ccccc2Cl)cc1C +COC(=O)C=C(C)c1ccc(-c2ccccn2)cc1 +COc1cccc(NC(=O)NCC(O)Cc2ccccc2)c1OC +O=C(NCc1ccco1)NCc1cccnc1Oc1cccc(F)c1 +CCNC(=O)C1(NC(=O)CNc2ccc(C#N)cc2)CCCCC1 +CC1CCCC(CNC(=O)CNC(=O)c2ccc(F)cc2F)C1 +CS(=O)(=O)c1ccc(CNC(=O)c2ccc3c(c2)OCCO3)cc1 +NC(=O)Cn1cc(NC(=O)NC2CCN(c3ncccn3)CC2)cn1 +CC1(C)OC(C(=O)N2CCCC2)C(C(=O)N2CCCC2)O1 +CC(C)Oc1ccc(-c2ccc(C(N)=O)c(N)n2)cc1 +O=c1c2ccccc2cnn1CC(O)c1ccccc1 +Cc1cc(C)n2nc(C)c(C(=O)NC(C)c3ccc(C#N)cc3)c2n1 +CCCCN(C)c1ncnc(Nc2nc(C)c(C)s2)c1N +O=C1NC2(CCN(S(=O)(=O)C3CC3)CC2)CC1c1cccnc1 +CCS(=O)(=O)c1ccc(NC(=O)NCc2cnn(C)c2)cc1 +CC(=O)Nc1cccc(C(=O)NC(C)COc2cccc(C)c2)c1 +Cc1nn2c(c1-c1ccccc1)NC(CO)CC2=O +OC(CN1CCN(c2ncccn2)CC1)c1ccco1 +CC(C)(O)CN1CCN(C(=O)C2CCCN2S(C)(=O)=O)CC1 +CC(=O)N1CCCC1CS(=O)(=O)c1ccccc1 +COc1cc(OC)cc(C(=O)NC(C)c2nnc3n2CCCCC3)c1 +Cn1cc(C(=O)NCc2ccc(F)c(Cl)c2)c2cccnc21 +CC1CN(Cc2nc3ccc(F)cc3[nH]2)CC(C)O1 +O=C(c1ccc(Cl)cc1)N1CCOC12CCCCC2 +CCOc1ncccc1NC(=O)N1CCN(c2cnccn2)CC1 +COc1ccc(-c2nn(C)c3c2C(=O)CCC3)cc1OC +COCC(=O)N1CCC(c2nc(C)cc(Oc3ccccc3C)n2)C1 +CCN(CC)C(=O)c1c(C)nc(N)nc1COc1ccc(OC)cc1 +Cc1ccc(S(=O)(=O)NCc2cccc(C#N)c2)cc1Cl +CCc1n[nH]c(NC(=O)c2scnc2C2CC2)c1Br +Cc1occc1CN(C)C(=O)Nc1ccc(=O)n(C)c1 +CN(C)C(=O)c1nccc(C(C)(C)C)c1OC1CC1 +O=C(c1scnc1C1CC1)N(C1CCCC1)C1CC1 +COCCNc1nc(-c2cc(C)ccc2OC)c(C)cc1C#N +Cc1cccc(S(=O)(=O)CC(=O)NCCC(C)C)c1 +O=C(Nc1ccccc1F)c1cc2cccn2cn1 +Cc1c(C(=O)Nc2nccn(C)c2=O)sc2cccc(F)c12 +Cc1nc(COc2cc3c(cc2CO)OCO3)cs1 +CC(NC(=O)c1cnn2c3c(cnc12)CCCCC3)c1ccccc1 +COC(=O)c1cc(CNc2ccn(-c3ncccc3Cl)n2)c[nH]1 +Cc1cccc(CC2Oc3ccc(N)cc3N(CCO)C2=O)c1C +C=CCc1cc(CNC(=O)N2CCC(CO)CC2)cc(OC)c1OC +Cc1c(F)ccc2c1C(C1COc3ccccc3O1)NCC2 +COc1ccc2ccccc2c1CNc1cnn(-c2ncccn2)c1 +CCn1nc(C)c(Cl)c1C(=O)NCCc1ccco1 +C#CCNC(=O)CN1CCCN(C)c2ccc(Cl)cc21 +CC(C)CC(=O)NCc1ccnc(-n2ccnc2)c1 +Cc1ccc(C(O)CCC(=O)N(C)Cc2ccccc2)c(C)c1 +CC(OC(=O)C1(c2ccccc2)CC1)c1ccccn1 +CCC(C)NS(=O)(=O)c1ccc(C(=O)N2CCCC(C)C2)cc1 +CCc1csc(CNC(=O)Nc2nc(CC)n(C)n2)n1 +CCOC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1ccc(SC)cc1 +C=CCNS(=O)(=O)c1ccc(NC(=O)C2CCC2)cc1 +CCc1nc2ccccc2n1CC(=O)NCc1nc(C)cs1 +Cc1ccc(OCCNc2ncnc3c2cnn3C)c(C)c1 +COCC(=O)Nc1ccc(OC)c(S(N)(=O)=O)c1 +CN(C)c1ccc(C(=O)Nc2ccccc2C(=O)NC2CC2)cc1F +CS(=O)(=O)N1CCN(C(=O)c2ccc(F)cc2)CC1 +O=C(NC1CC2(CCCCC2)Oc2ccccc21)c1ccco1 +CC(NC(=O)NC(C)c1cccs1)c1ccc2c(c1)CCC(=O)N2 +O=C(C(c1ccccc1)C(F)(F)F)N1CCCC1 +Cc1cc(C)n(-c2cccc(-c3ccc(N)nc3)c2)n1 +CC(=O)Nc1ccc(NC(=O)c2ccc3c(c2)CCC3)cc1Cl +Cc1ccccc1Cn1cc(NC(=O)c2nnc3ccccc3n2)cn1 +Cc1cc(N2CCCC2)nc2sc3c(=O)[nH]cnc3c12 +CCc1ccccc1C(=O)N1CCCCC1CCCOC +COc1ccc(NC(=O)CCc2ccc3c(c2)OCO3)cc1 +CC(=O)c1cccc(S(=O)(=O)NC(C)c2cc3ccccc3o2)c1 +CCN(Cc1noc(C2CC2)n1)C(=O)c1ccc2c(c1)OCCN2C +Nc1cc(Br)ccc1N1CCOCC1 +N#Cc1ccc(NCC(=O)c2ccc3c(c2)OCO3)cc1 +CC(C)NS(=O)(=O)c1ccc(NC(=O)c2cccs2)cc1 +CCc1cccc2c(C(C)=O)cn(CC(=O)N3CCCCC3)c12 +O=C(NCC1(O)CCc2ccccc21)NC1CCCCC1 +CCOC(=O)CN(C)C(=O)c1cc(C2CC2)on1 +COc1ccc(Cl)cc1NC(C)c1ccccn1 +Cc1ccc(Nc2nc(N)nc(CSc3ccccn3)n2)cc1 +CNc1ccc(S(=O)(=O)NC)cc1NC(=O)C1CC1c1ccco1 +CCc1noc2ncnc(Nc3ccccc3C)c12 +Cc1ccc(CNc2ccc3c(c2)OCC(=O)N3CC(N)=O)cc1 +N#Cc1ccccc1NCc1ccc2c(c1)OCCO2 +N#Cc1ccnc(SCc2nc(-c3ccc4c(c3)OCO4)no2)c1 +Cc1ccc(NC(=O)Cn2cnc3ccccc3c2=O)c(O)c1 +CCNC(=O)CNc1cc(NC(C)=O)ccc1OC +COc1ccc(SCCC(=O)NCc2n[nH]c(=O)[nH]2)cc1 +O=C(Nc1cc2c(cc1Cl)OCCO2)c1ccoc1 +Cn1c(=O)[nH]c2cc(C(=O)N3CCCC(n4cccn4)C3)ccc21 +COCCNC(=O)Cn1nc(-c2ccc3c(c2)OCCO3)ccc1=O +CC(C)NC(=O)Cc1ccc(NC(=O)NC(C)c2nccs2)cc1 +COc1ccsc1C(=O)N1CCC(NC(=O)c2cc(C)on2)CC1 +CCCCOc1ccc(NC(=O)c2cc(C(N)=O)cs2)c(C)c1 +CCN(CCc1ccccc1)C(=O)c1[nH]nc(C)c1Br +CCCSc1ccc(NC(=O)NCc2nnc(CC)s2)cc1 +CCOc1ccc2c(C(=O)NC(C)c3cnn(C)c3)cc(=O)oc2c1 +CC(=O)N1CCc2cc(-c3nc4sc(C)nn4c3CO)ccc21 +Cc1noc(C)c1CC(=O)NC1CCCNC1=O +CCCn1c(=O)n(CCC(=O)OC)c2ccccc21 +COc1cccc(-c2cnn3c(N)c(C#N)nnc23)c1 +Cn1cnc(CNC(=O)N(CCc2ccccc2)Cc2ccccc2)n1 +O=C(Cn1cncn1)Nc1ccccc1-c1ccc(=O)[nH]n1 +CC(=O)c1cccc(OC(=O)Cn2c(C)c(C)sc2=O)c1 +Cn1nccc1C(=O)N1CCCC(c2cc3ncccc3[nH]2)C1 +Cc1nc2c(N(C)Cc3ccccc3)nc(N)nc2n1C +CS(=O)(=O)NCC1(c2ccc(Br)cc2)CCC1 +COc1ccc(OC)c(NC(=O)CN2CCc3ccccc32)c1 +CC(=O)N1CCN(CC(=O)c2c(C)[nH]c3ccccc23)CC1 +N#Cc1ccccc1-c1ccccc1C(=O)OCC1CCC(=O)N1 +COc1ccccc1OCc1nc(-c2ccccc2OC)no1 +CCc1ccc(C2COCCN2C(=O)c2scnc2C2CC2)o1 +Cc1nn(CCC(=O)Nc2ccnn2C(C)C)c2ccccc12 +O=C(Cn1ccc2ccc(F)cc21)Nc1ccncc1 +Cc1ccc(F)cc1NC(=O)C(C)Sc1nncs1 +Cc1ccccc1C1CC1C(=O)NC(C)c1ccc(-n2ccnc2)cc1 +CC(C)Oc1ccc(NC(=O)c2cnccn2)cc1 +CC1(C)OCC2(CO1)CN(C(=O)c1ccccc1Cl)C2 +Cc1cccc(-c2ccc3c(ccn3CC(=O)Nc3cnn(C)n3)c2)c1 +COc1ncccc1CNC(=O)c1n[nH]c(=O)c2ccccc12 +CC(Nc1cccc(N2CCCC2)c1)c1ccc(S(C)=O)cc1 +CC1CC(C)CN(C(=O)CCC(=O)c2ccc3c(c2)OCCO3)C1 +CC(=O)c1ccc(Cl)c(Cl)c1OCC(=O)NC(C)C1CC1 +O=C(Nc1c[nH]cc(Br)c1=O)c1n[nH]c2c1CCC2 +CC1CCC(N(C)C(=O)CS(=O)(=O)c2ccccn2)CC1 +CCn1nnc2cc(C(=O)NCCCN3CCCC3=O)ccc21 +CCCCN(C)S(=O)(=O)N1CCN(Cc2ccccn2)CC1 +CCNc1cc(S(=O)(=O)N2CCOCC2)ccc1OC(C)C +COc1ccc(S(=O)(=O)C(C)C(=O)Nc2c(C)cccc2C)cc1 +N#CC1(C(=O)NCc2cccc(C(=O)N3CCCCC3)c2)CCCC1 +CCCc1cc(=O)[nH]c(SCC(=O)Nc2ccccc2F)n1 +CCN(CC(=O)NC(C)C)C(=O)c1cnn(C(C)C)c1C(F)(F)F +CC1CCCN(S(=O)(=O)N(C)CCc2ccccn2)C1 +CCOC(=O)CN1CC(NC(=O)OC(C)(C)C)CC1=O +O=C(Nc1cc(Cl)ccc1O)c1cc(=O)c2ccccc2o1 +Nc1cc(F)c(NCCc2ccccc2F)c(F)c1 +Cc1noc(NC(=O)c2cccc(NC(=O)C3CC3C)c2)n1 +COc1ccccc1C(NC(=O)NC1(CCO)CCC1)c1ccco1 +Cc1ccc(CC(=O)Nc2sc3c(c2C(N)=O)CCCC3)cc1C +Cc1occc1C(=O)NCC(=O)Nc1ccc2c(c1)CCC(=O)N2 +O=C(Oc1ccccc1F)C1CCCN1C(=O)Cc1cccs1 +COc1cccc(NCC(O)COc2ccc(F)cc2F)c1 +O=C(CCc1nc(-c2ccccc2)no1)NC1COC2(CCCC2)C1 +Cc1cccc(NC(=O)Cn2c(CO)nc3ccccc32)c1 +Cc1cc(C(C)NC(=O)N2CCOC(C)(C)C2)c(C)s1 +CNC(C(=O)OC)c1cc(Cl)c2c(c1)OCCCO2 +O=C(Nc1nc(C(=O)N2CCc3ccccc32)co1)c1ccco1 +Cc1ccc(C(CNC(=O)Nc2ccccc2)N2CCOCC2)cc1 +CS(=O)(=O)N1CCC(NC(=O)CCOc2ccccc2)CC1 +CCOC(=O)CN(C)S(=O)(=O)c1ccc(C)c(C(F)(F)F)c1 +O=C(CCc1nc(-c2ccc(F)cc2)no1)Nc1nccs1 +COc1ccc(NC(=O)c2cc3nc(C)cc(C)n3n2)cc1OC +CCCS(=O)(=O)NC1CCc2c(Cl)cccc21 +CC(C)CNC(=O)NCCn1cnc2ccccc21 +COc1ccncc1NC(=O)CCCc1cc(F)ccc1F +O=S(=O)(Nc1ccncc1)c1ccc2c(c1)CCCC2 +COC(=O)C1CC(O)CN1C(=O)Nc1ccc(Cl)c(Cl)c1 +Cc1ccc2cc(CNc3ccc4[nH]ncc4c3)c(=O)[nH]c2c1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)OCC(F)F +O=C(Cn1ncc2c(=O)oc3ccccc3c21)NCc1cccnc1 +CCOC(=O)C1CCN(S(=O)(=O)c2c(C)n[nH]c2C)CC1 +COc1ccc(CCCNC(=O)C2CC(=O)N(C3CC3)C2)cc1 +CCOC(=O)CC(C)CNC(=O)N1CCCC(CC)C1 +CC(C)CC(=O)Nc1ccc(NC(=O)N(C)Cc2ccccn2)cc1 +CCN(CC(C)(C)O)c1ccc(S(C)(=O)=O)cc1S(C)(=O)=O +O=C(c1nc(Cc2c[nH]c3ccccc23)no1)N1CCOCC1 +CC(C(=O)NCc1ccccc1)N(C)Cc1nc2ccccc2s1 +CCCC(=O)Nc1ccc(NCC(=O)N(C)c2ccccc2)cc1 +CC(C)C(NC(=O)OC(C)(C)C)n1nnc2ccccc21 +CCOC(=O)c1ccc(NC(=O)N2CCCC2c2cc(C)no2)cc1 +CCNC(=O)N1CCN(C(=O)C(c2ccccc2)N2CCCC2)CC1 +COc1ccc(OC)c(-n2nnc(CO)c2C2CCCCC2)c1 +O=C(NCc1ccc2c(c1)OCO2)c1ccc2[nH]ccc2c1 +Cc1nc(NC(C)C)nc2c1ncc(=O)n2C(C)C +O=C(NCC(=O)N1CCOCC1)c1ccc(Cl)cc1Cl +CCn1c(SCC(=O)NC(C)(C)C#N)nnc1-c1ccco1 +Cc1nn(-c2cccc(Cl)c2Cl)c(N)c1C#N +c1ccc(-n2nnnc2N2CCN(c3nccs3)CC2)cc1 +COc1ccc(C)cc1NC(=O)Cn1cnc(C)cc1=O +O=C(NCCNc1ncccn1)c1ccc(Cl)cc1F +COc1ccc(-c2cc(C)c3nc(N)nn3c2)cc1Cl +COC(=O)c1ccc(Cn2c(C)cc(=O)c3cc(Cl)ccc32)o1 +COc1ccccc1OCC(=O)Nc1ccc(Cl)cn1 +Cc1cc(C)n2nc(SC(C)c3nc(C(C)(C)C)no3)nc2n1 +CC(C)c1ccc(C(=O)N2CCC(CO)CC2)cc1 +COc1ccc(CC(=O)NCC2(c3ccccc3)CC2)cc1OC +COC(=O)CCn1nc(C)c(CN2CCNC(=O)C2C(C)C)c1C +Cc1noc(-c2cccnc2)c1C(=O)NCc1cc(F)cc(F)c1 +CCOc1ncccc1C(=O)OCC(=O)NC1(C#N)CCCCC1 +COc1cccc(-c2cc(C(=O)Nc3nc4c(s3)CCC4)[nH]n2)c1 +COc1cccc(OCc2nc(C)cc(N)n2)c1OC +CC(=O)NC(CC(=O)Nc1cc(C)on1)c1ccc(Cl)cc1 +Cn1cc(C(=O)N2Cc3ccccc3C(c3ccccc3)C2)ccc1=O +CC1CCCCC1NC(=O)c1ccccc1S(C)(=O)=O +CN(C(=O)C12CCC(C)(OC1=O)C2(C)C)C1Cc2ccccc2C1 +CC(=O)N(C)Cc1cccc(NC(=O)c2ccn(C)c(=O)c2)c1 +O=C(CNC(=O)c1cc(F)cc(F)c1)NCCC1=CCCCC1 +Cc1nc(CC(=O)N2CCCC2CO)c(C)s1 +CC(Nc1ncnc2c1cnn2CCC#N)c1ccccn1 +CC(=O)N1CCN(C(=O)c2csc(Nc3ncccn3)n2)CC1 +CC(=O)NC(Cc1ccccc1)c1sccc1C +CC(C)(C)c1ccc(C(=O)Nc2nnc(C3CCCO3)o2)cc1 +CC(C)Oc1ccc(-n2c(=O)[nH]c3ccccc32)cc1 +O=C(NC1CCCCCC1)c1cnn2c1SCC2 +CN(C(=O)c1cccc(CCC(C)(C)O)c1)C1CCCCC1O +Cc1nc(Nc2ncnc(N3CCCCC3C)c2N)sc1C +CCc1ccc(C2CCCN2C(=O)NCCCc2nc(C)no2)o1 +COc1ccc(OC)c(CN(C)C(=O)C2CC=CCC2)c1 +CCCCNC(=O)c1ccc(S(=O)(=O)NC2CC2)cc1 +CCc1ccc(C(C#N)N(C)C(=O)c2cccnc2)cc1 +Cc1c(N)cccc1-c1nnnn1CCC(F)(F)F +CCN(CC)C(=O)c1ccc(S(=O)(=O)Oc2cccc(C)c2)cc1 +CC(C)(C)C(NC(=O)Cn1cnnn1)c1cccs1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)Nc1nc3ccccc3[nH]1)O2 +Cc1ncc(CNC(=O)N(CCCO)C2CCc3ccccc32)s1 +CC(NC(=O)C1CC(=O)Nc2cc(F)ccc21)c1ccccc1F +O=C1N2CN(CCO)CN3C(=O)N4CN(CCO)CN1C4C23 +Cc1cc(C)n(CC(=O)Nc2ccccc2)c1-c1nc(C2CC2)no1 +Cc1ccnc2nc(C(=O)Nc3ccc(F)c(Cl)c3)nn12 +Cc1cc(C)n(-c2nc3nonc3nc2Nc2ccccc2F)n1 +N#CCCN(CCC#N)C(=O)CN1CCN(c2nccs2)CC1 +Cc1ccc(CNC(=O)c2cc3c(nc2N)CCCC3)cc1 +COCc1cccc(NC(=O)C(C)Sc2nnnn2C2CC2)c1 +CC(CO)NC(=O)CC(C)NC(=O)c1ccccc1 +CC(Oc1ccc(-c2ccccc2)cc1)C(=O)NCc1cccnc1 +CN(C(=O)c1cc2c(s1)CCC2)C1(C#N)CCC1 +Cc1ccc(-n2nnc(CO)c2C(F)(F)F)cc1 +COC(=O)C(NC(=O)c1ccc(F)cc1)C(F)(F)F +COc1cc2c(c(OC)c1)C(c1ccc[nH]c1=O)NCC2 +CCOC(=O)CSc1nnc(Cc2c(C)[nH]c(=O)[nH]c2=O)o1 +CC(C#N)Cc1ccc2cc(N3CCOCC3)ccc2n1 +COc1ccc(C(O)CNC(=O)CC(C)C)cc1Cl +CCN(CC(C)C#N)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +CCOC(CC)C(=O)Oc1ccc(C#N)cc1Cl +CC(C)(C)OC(=O)Nc1cc(NC(=O)C2CC=CC2)ccc1F +CCCC(=O)N1CCN(c2ncnc3c2cnn3C)CC1 +O=C(Nc1ccc2c(c1)OCO2)c1cccn(Cc2ccccc2)c1=O +O=C(CSc1nnc(C2CCCCC2)o1)c1ccc(F)cc1F +COCC1CN(C(=O)Cc2cccc(F)c2)Cc2ccnn2C1 +Cc1ccc2cccc(C(=O)NCCOc3ccccc3)c2n1 +CC(Cn1cncn1)NC(=O)c1cc(S(C)(=O)=O)ccc1Cl +Cc1n[nH]c(C)c1-c1nc(C2(c3ccccc3)CC2)no1 +COc1ccc(C(CC(=O)NC2CCCCC2C)NC(C)=O)cc1 +O=C(c1ccccn1)N1CCN(C2CC2)CC1c1ccccc1 +O=C(Nc1cccc(C(=O)N2CCCCCC2)c1)c1ccco1 +Cc1ccc(-c2nc(CNC(=O)Cc3ccccc3C)no2)cc1 +O=C(NCc1cccs1)c1cc(F)c(F)cc1Cl +CC(C)n1nc(-c2ccccc2)cc1NC(=O)NC1CCC(O)CC1 +O=C(NCCNS(=O)(=O)c1ccccc1Cl)c1cccnc1 +CN(C)C(=O)Cc1ccc(NC(=O)Cc2ccc[nH]2)cc1 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1c(C)cc(C)cc1C +O=C(c1n[nH]c2c1CCC2)N1CCN(c2ncnc3ccccc23)CC1 +CC(CC1CCCC1)C(=O)N1CC(C(N)=O)CCC1C +COc1cc(OC)c(NC(=O)NCc2nnc3ccccn23)cc1F +CC(C)N(CCCO)S(=O)(=O)c1cccnc1 +Cc1cc(NC(C)Cn2cccn2)nc(C(C)C)n1 +COc1cccc(OC)c1C(=O)Nc1cccc(NC(C)=O)c1C +COc1ccc(CN(C(=O)c2cccc(NC(C)=O)c2)C2CC2)cc1 +Cc1nnc(SC(C)C(=O)N2CCC(C)CC2)n(N)c1=O +c1cc(-c2ccn(CC3CCCO3)n2)cc(-c2nccs2)c1 +COc1ccccc1-c1noc(-c2ccc(=O)[nH]n2)n1 +CCOC(=O)CSc1nc(-c2ccccn2)ncc1OC +CCCCNC(=O)Cc1csc(NC(=O)C2CCC(=O)N2)n1 +NC1=NC2(CCCCC2)n2c(nc(=O)c3ccccc32)N1 +CCc1ccc(OCC(=O)Nc2cc(NC(C)=O)ccc2F)cc1 +CCN(C(=O)CN1CCOC(C(N)=O)C1)C(C)c1ccc(F)cc1 +CCOc1ccc(Br)cc1NC(=O)N1CCNC(=O)C1 +O=C(CSc1ccncc1)Nc1ccc(OC(F)(F)F)cc1 +COc1ccc(S(=O)(=O)N2CCNC(=O)CC2)cc1 +Cc1ccc(S(=O)(=O)Nc2ccc3[nH]ncc3c2)cc1C +Cc1cc(NC(=O)c2ccc3c(c2)CCC(=O)N3)c2ncccc2c1 +CC(C)n1c(CNC(=O)c2[nH]nc3c2CCC3)nc2ccccc21 +CNC(=O)NCC(=O)Nc1cc(C)nn1Cc1ccccc1 +CC(=O)N(C)CC(=O)NCc1ccc(OC(C)C)nc1 +CC(CNc1nc2ccccc2c(=O)[nH]1)N1CCOCC1 +O=C(CNC(=O)c1cc2scnc2[nH]1)NC1CCCC1 +Cc1ccc(C(=O)N2CCC(CC(N)=O)CC2)c(C)n1 +CN(C)C(=O)N1CCC(C(=O)NCCc2ccccn2)CC1 +O=C1CCC2C(CCN2C(=O)c2ccc3[nH]ccc3c2)N1CC1CC1 +Cn1c(N2CCC(C(=O)N3CCCC3)CC2)c(C#N)c(=O)n(C)c1=O +CCSc1ccc(-c2cn3c(nc4cc(N)ccc43)[nH]2)cc1 +CN1CCC(NC(=O)CCNC(=O)c2ccc(F)cc2F)C1=O +O=C(CC1=CCCCC1)NCc1ccccc1N1CCOCC1 +Cc1nn(C(C)C)c(C)c1Nc1nccc(C(F)(F)F)n1 +C=CCNC(=O)c1cccc(S(=O)(=O)N2CCOC(C)(C)C2)c1 +CNS(=O)(=O)c1ccc(C(=O)NC(C)c2ccc(C)c(F)c2)o1 +Cc1cc(C)c2c(c1)OCCCC2(C#N)N1CCOCC1 +CC1CCCN(S(=O)(=O)N(C)Cc2cccnc2)C1 +CCOc1ccc(NC(=O)c2cnc3c(c2)c(C)nn3C)c(C)c1 +COc1ccccc1CCNS(=O)(=O)N(C)C +CC(=O)Nc1cccc(OCC(=O)Nc2ccc(C)c(Cl)c2)c1 +COc1ccc(C(=O)NC2CCN(c3cc(C)cc(C)c3)C2=O)cc1 +CCOC(=O)C1(CC#N)CCN(C(=O)OC(C)(C)C)CC1 +CC1(C)C(C(=O)NCCc2cccs2)C1(C)C +Cc1cc(Cc2ccccc2)nc(C2CN(S(C)(=O)=O)C2)n1 +Cc1n[nH]c(C)c1NC(=O)CN(C)c1ccccc1N(C)C +Cc1noc(C)c1CN1C(=O)C(C)Nc2cc(F)c(F)cc21 +COc1ccccc1CN(Cc1cccs1)C(=O)c1ccc[nH]1 +CCn1cc(C2CCN(c3nccc(OC)n3)CC2)cn1 +CSc1cc(C(=O)Nc2ccccc2Br)ccn1 +CS(=O)(=O)c1cccc(OCCn2ccnc2-c2cnccn2)c1 +CS(=O)(=O)Nc1ccccc1NC(=O)c1ccc(F)cc1 +CC(C)NC(=O)CSc1nc(-c2cccnc2)n[nH]1 +CC(C)(C)n1cc(C#N)cc1NC(=O)C1CC2CCC1O2 +O=C(c1ncn(-c2ccccc2)n1)N1CCSc2ccncc21 +CCOCC(=O)NCCC1CCN(C(=O)c2ccc(F)cc2)CC1 +CCCc1nnsc1C(=O)NCC(O)c1ccc2c(c1)CCO2 +Cc1nc(CCNC(=O)c2c(O)cc(F)cc2F)cs1 +O=C(Nc1ccnn1Cc1ccccc1)c1ccccc1F +CN(C)C(=O)c1ccc(NC(=O)CCc2ccccc2N)cc1 +COc1cc(C(=O)N(C)C2(C#N)CCC2)cc(OC)c1C +O=C(NCCN1CCOCC1)c1ccc2ccccc2c1O +CCS(=O)(=O)NC(C)c1ccccc1C(F)(F)F +COc1ccc(C(O)Cn2cc(N)cn2)cc1C(C)(C)C +OC(Cn1cnc2ccccc21)c1ccc(F)cc1 +CN(CCO)C(=O)Nc1ccccc1SC(F)F +Nc1nc(COC(=O)c2ccccc2)nc(Nc2ccccc2)n1 +Cc1c(C(=O)N(C)C)sc(NC(=O)CC#N)c1C#N +Cc1nnnn1-c1cccc(NC(=O)C(C)Cc2ccccc2F)c1 +COCC(C)NC(=O)Cc1csc(-c2ccc(F)cc2)n1 +Cn1cnc(CNC(=O)Nc2ccc3c(c2)oc2ccccc23)n1 +COC(=O)c1[nH]c(C)cc1NS(=O)(=O)c1cccc(F)c1F +C=CCNC(=O)CSc1nncn1-c1cccc(Cl)c1 +COc1c(C(=O)Nc2nccs2)nnn1Cc1ccccc1Cl +COc1ccc(C(=O)N(C)C2CCOCC2)cc1N +Cc1cccc(NC(=O)CNC(=O)NCc2ccccc2)c1C +Cc1ccc(C23COCC(=O)N2CCCN3)cc1C +COc1ccc(N2CCCC(C(=O)N3CCOCC3)C2)nn1 +O=C(NCCCc1ccccc1)c1cc2c(cn1)OCC2 +O=c1c2ccccc2sn1Cc1nc2ncccn2n1 +CCc1nc(CN2CCN(C(=O)c3c(C)nn(C)c3C)CC2)cs1 +Cc1cc(C)n2nc(C)c(C(=O)NCc3ccc(C)s3)c2n1 +CC(C)CC(O)C1CCN(C(=O)c2cc3c([nH]c2=O)CCC3)CC1 +CC(=O)c1ccccc1NCc1cc(=O)n2c(C)csc2n1 +CC(=O)c1ccc(Nc2ncnc(Oc3cccnc3)c2N)cc1 +CCN(CC)C(=O)CCC(=O)NCc1ccc(O)c(F)c1 +O=C(NCc1cscn1)c1cc2cccc(Br)c2o1 +C#CCCCOC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +Cc1nc(C)c(C(=O)N(C)Cc2nc(-c3ccccc3)c[nH]2)o1 +COc1ccc(OC)c(C(=O)NCCNC(C)=O)c1 +Cc1ccc2c(Cc3nc(-c4ccncc4)no3)c[nH]c2c1 +C#CCNC(=O)CCC(=O)c1cc(Br)ccc1OC +CC(=O)Nc1cccc(NC(=O)CSc2ccccc2F)c1 +CCc1noc(CC)c1CNC(=O)NC(C)C(C)(C)C +CNC(=O)NC(C)(C)C(=O)N(C)Cc1ccoc1 +CCn1ncc(CN2CCc3n[nH]c(-c4cccc(F)c4)c3C2)c1C +O=C(NCc1cc(-c2ccccn2)n(C2CCCC2)n1)c1ccco1 +O=C(NCC1CCN(C(=O)Oc2ccccc2)CC1)c1ccncc1 +COc1cc(C)ccc1OCC(=O)Nc1ncccc1C +COc1cccc(CNC(=O)c2cnc3snnc3c2)c1 +CCC1c2ccccc2CCN1C(=O)c1ccc(F)nc1 +CNC(=O)C1CCCCN1C(=O)c1ccc(C(C)C)cc1 +COCCN(Cc1nccs1)C(=O)c1c(C)nc2ccc(C)cn12 +COCCNC(=O)c1cc(-c2ccco2)n(-c2cccc(Cl)c2)n1 +COc1ccc(C)cc1C(=O)CSc1nnnn1C +CNC(=O)COc1cccc(OCc2cn3ccccc3n2)c1 +CC(=O)N(CCc1ccccc1)CC(=O)NCc1ncc(C)s1 +Cc1nnc(-c2cc3ccccc3n2CC(=O)Nc2ccccc2)o1 +CCC(OC(=O)c1cccc(N)c1)C(=O)Nc1ccccn1 +CC1(C)OC2C(CO)OC(n3cc(F)c(N)nc3=O)C2O1 +CCOCc1ccccc1NCc1cc(OC)c2c(c1)OCCO2 +CC(CNC(=O)N1CCCC1C1CCC1)c1ccncc1 +Cc1noc(-c2ccc3nc(C4CC4)[nH]c3c2)c1N +Cc1ccc2c(c1)C1(CCN(C(=O)OC(C)(C)C)CC1)C(=O)N2 +O=C(OCCn1cccn1)c1cc(=O)[nH]c2ccccc12 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)C1CC1c1ccccc1F +COC(=O)c1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1 +CCc1ccc2oc(-c3cccc(NC(=O)c4nc[nH]n4)c3)nc2c1 +Cc1n[nH]c(C)c1CCC(=O)Nc1ccc(F)c(F)c1 +O=c1[nH]cc(Cl)cc1C1NCCc2c(F)cc(O)cc21 +O=C(c1cccs1)C1NCCc2c1ccc1cc[nH]c21 +CC(C)(C)c1nnc(SCC(=O)Nc2cccc(C#N)c2)n1N +CCOc1ccc(S(=O)(=O)NC2CCCC2)cc1OCC +CCC(CC)NC(=O)C(C)Sc1nncs1 +O=C(Nc1ccc2c(c1)OCCO2)c1cncc(-c2cccs2)c1 +Cc1c(NC(C)C(=O)N(C)CCC#N)c(=O)n(-c2ccccc2)n1C +CCCCNC(=O)CNc1ccc(Cl)c(C#N)c1 +Cc1ccc(-c2n[nH]c3c2C(c2cccc(O)c2)N(C)C3=O)cc1 +O=C(c1cnccn1)N1CCc2[nH]nc(Nc3ccccc3)c2C1 +CC(NC(=O)N1CCCC1c1ccc2c(c1)OCO2)c1ccncc1 +Cc1cc(C)n(Cc2cccc(C(=O)Nc3ccc4c(c3)COC4)c2)n1 +C#CCn1c(C2CC(=O)N(C3CCCC3)C2)nc2ccccc21 +CCCCNC(=O)COc1nc(N2CCCC2)nc(C)c1C +COc1ncccc1NC(=O)NCC(O)c1cccc(Cl)c1 +O=C(Cn1nnc(-c2ccccc2)n1)N1CCOC2CCCC21 +Cc1ccccc1-c1nnn(CC(=O)c2ccccc2)n1 +O=C1CCN(C(=O)c2ccc(F)cc2)c2ccccc2N1 +CC(NC(=O)c1cccc(-n2cnnn2)c1)c1nnc2ccccn12 +Cc1ccc2c(Cn3cnc4ccccc4c3=O)cc(=O)oc2c1 +O=C(Nc1nnc(Cc2ccc3c(c2)OCO3)o1)c1cccs1 +CCC(C)NS(=O)(=O)c1ccc(C(=O)Nc2cc(C)on2)cc1 +COc1cccc(-c2noc3ncnc(NCc4ccccn4)c23)c1 +CNC(=O)c1cn(CCCOC)c2cccc(N)c2c1=O +COc1ccc(C(=O)Nc2ccc(N3CCCC3=O)cc2)c(O)c1 +O=C(Nc1ccc(-n2ccnc2)nc1)C1CCCc2ccccc21 +COc1ccccc1N1CCN(CC(=O)NCc2ccccc2)CC1 +CC(=O)c1ccc(NCC(=O)N2CCCC(C)C2)cc1 +Cc1ccc(C(CNC(=O)NC2CCCCC2)N2CCOCC2)o1 +COCC(C)N1CC(C(=O)N2CCCC(C)C2)CC1=O +CCC(CC)NC(=O)c1ccc(Cn2ccnc2)cc1 +Cn1cc(C(N)=O)cc1C(=O)OCc1ncc(-c2ccc(F)cc2)o1 +CC(C)c1nc2cc(C(=O)NCC(C)(C)N3CCOCC3)ccc2o1 +CCn1cnnc1SC(C)C(=O)Nc1ccc(OC)c(Cl)c1 +COc1ccc(SCC(=O)N(C)CCC(F)(F)F)cc1 +CN(C)c1ncc(NC(=O)c2cc3ccccc3[nH]2)cn1 +COC(=O)N1CCCC1C(=O)N(C)c1ccc(Br)cn1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCc2ncn(C)n2)n1 +Cn1cc(O)c(=O)cc1CN(CCO)Cc1ccccc1 +Cc1ncsc1C(=O)Nc1cc(C#N)ccc1OC(F)F +CC(C)(C)c1ccc(SCC(=O)Nc2ncccn2)cc1 +Cc1ccc(S(C)(=O)=O)cc1NCc1ccc(-n2cccn2)cc1 +CC(=O)Nc1ccc(C)c(NCC(=O)Nc2cccc(C(C)=O)c2)c1 +COc1cccc(CCC(=O)NC2COc3c(cccc3OC)C2)c1 +CCc1onc(C)c1NC(=O)N(C)C(C)C1(C)CC1 +CC(C)c1nnc(SCC(N)=O)c2c1cnn2-c1ccccc1 +Cn1nccc1NC(=O)CCc1c[nH]c2ccccc12 +COC(=O)c1ccc(C(=O)N2CC(c3ccc(F)cc3)CC2C)nc1 +CC(C)C(CNC(=O)Nc1cc(F)cc(F)c1)N1CCOCC1 +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1cccc2c1OCO2 +COCC(C)N(C)c1ccc(N)cc1C(=O)OC +CN1CCC(Nc2ccc(C(=O)NC3CCOCC3)cc2)C1=O +C=CCOC(=O)N1CC(c2ccccc2)NCC1(C)C +CCC1CN(C(C)c2nc3sc(C)c(C)c3c(=O)[nH]2)CCO1 +CCC(=O)CSc1nnc(Nc2ccccc2)s1 +Cc1nc(C2CCCN2C(=O)c2cc(Br)c[nH]2)no1 +O=C(Nc1ccc(CN2CCCC2=O)cc1)c1ccc(F)cc1Cl +Nc1cc(Cc2ccccc2Br)n[nH]1 +N#Cc1ccccc1NC(=O)CN1C(=O)CCc2ccccc21 +N#Cc1cccc(OCCn2c(-c3ccccn3)noc2=O)c1 +Cc1ccccc1-n1ncc(C(=O)NC(C#N)CC(C)C)c1C +CC(C)CCNC(=O)NCc1cn2cc(Br)ccc2n1 +COc1ccc(S(=O)(=O)NCCCCO)c(C)c1 +O=C(Cn1cnc2ccccc2c1=O)NCCc1ccc(F)cc1 +CC(C)(C)N1CC(C(=O)N2CCCCC2)CC1=O +O=C(NCc1ccc2c(c1)OCO2)C1CCN(c2ccccc2)CC1 +CC(=O)Nc1ccc(-c2cn3ccc(C)nc3n2)cc1 +CC1CC=CCC1COC(=O)CCNC(=O)c1cccs1 +C=C(C)Cn1nnc(C#N)c1-c1ccc(OC)c(OC)c1 +CCCc1noc(CCC(=O)N2CCCC2c2ccncc2)n1 +CC(NC(=O)CN1CCN(C(=O)c2cccs2)CC1)c1ccco1 +Cn1cc(C(=O)NC(C(N)=O)c2ccccc2)c2ccccc21 +N#Cc1ccc(F)c(C2NCCc3cccc(F)c32)c1 +Cc1cc(NC(=O)NCC(O)c2ccc3ccccc3c2)n(C)n1 +COCC(=O)N1CCC(Nc2cc(Cl)ccc2C#N)CC1 +Cc1ccc2cccc(NC(=O)NC3CCC(O)CC3)c2n1 +CCc1nnc2n1CCN(c1ncc(C(F)(F)F)cc1Cl)C2 +Cc1nc(-c2ccc(Cl)cc2Cl)cc2c1CNC2=O +O=C1CCCN1CCc1nc(-c2ccc(Cl)cc2Cl)cs1 +CC(Cc1ccccc1)Nc1nc2ncnc-2c(N)n1C +O=C(Cc1cccs1)NC1CC(=O)N(c2ccc(F)cc2)C1 +COc1ccc(C(=O)Nc2ccccc2SCCC#N)c(OC)c1 +CCN(CC1CCOC1)C(=O)c1nc(C)n(-c2ccc(Cl)cc2)n1 +Cc1ccc(C(=O)Nc2ccc(Cl)cn2)c(N)n1 +O=C(Nc1ccccc1O)c1cc(-n2ccnc2)ccn1 +N#Cc1ccc(S(=O)(=O)c2ccc3c(c2)OCO3)cc1 +COc1cc2nc(NC(=O)c3ccccc3)sc2cc1OC +O=C(Cn1ccc(C(F)(F)F)n1)Nc1cccc(Cn2ccnc2)c1 +NS(=O)(=O)Cc1ccc(NC(=O)CCc2cccnc2)cc1 +COc1ccc(F)cc1NC(=O)c1cc(C)nc2c1cnn2C +Cc1ccc(-c2cc(C(=O)NCC(=O)N3CCCCC3)on2)cc1 +CC1CCN(C(=O)Cn2nnc(-c3ccccc3)n2)CC1 +Cc1nn(C)c2ncc(NC(=O)c3ccc(F)cc3)cc12 +COc1ccc(C(C)=O)cc1S(=O)(=O)N1CCCCCC1 +CCCn1c(=O)oc2cc(NC(=O)NCc3cccc(F)c3)ccc21 +Cc1cccc(NC(=O)c2ccc(NC(N)=O)cc2)c1 +Cc1cccc(-c2noc(CNC(=O)c3ccc(F)cc3)n2)c1 +Cc1ccccc1NC(=O)CN1CCN(c2ncccn2)CC1 +COC(=O)c1cccc(CC(=O)N(CC(F)(F)F)C(C)C)c1 +CSc1ccccc1C(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +Cc1cc(Br)c2nc(-c3ccco3)c(C#N)n2c1 +Cn1ncc(CN2CCCC3(C2)OCCO3)c1C(F)(F)F +Cc1ccccc1NS(=O)(=O)c1ccc(C(=O)NCCCO)cc1 +CCC(=O)NCC1CCCN(C(=O)Nc2cc(F)ccc2F)C1 +CC1CCc2c(C(=O)N(CCC#N)CCC(F)(F)F)csc2C1 +COc1ccc(Cl)cc1N(C)C(=O)COc1cccc(C(N)=O)c1 +Cn1cc(C(N)=O)cc1C(=O)Nc1nc(-c2ccccc2)cs1 +Cc1ccccc1C1CCN(C(=O)C2CCN(C(=O)N(C)C)CC2)C1 +CCOC(=O)c1ncn(-c2ccccc2Cl)c1N +CCOc1ccccc1NCC(=O)NC1CCN(C(C)=O)CC1 +CCOc1ccc(NC(=O)CSc2nnnn2C2CC2)c(C)c1 +NC(=O)c1nc(Nc2ccccc2)sc1NC(=O)CC1CCCC1 +CCN(CCC#N)C(=O)Cc1c(F)cccc1Cl +CCCCS(=O)(=O)NCC(=O)Nc1cccc(C#N)c1 +COC(=O)C1CN(Cc2cn(C)nc2C2CCCCC2)CC(C)O1 +Cc1cccc(C(C)CNC(=O)N(C)CCN2CCCC2=O)c1 +Nc1nc(-c2cccnc2)ncc1C(=O)Nc1ccccc1F +CC(C(=O)Nc1ccccc1N)n1ccc(=O)cc1 +COC(=O)c1ccc(NC(=O)NC(C)CCCO)cc1C +COc1ccc(CNC(=O)CCc2cccs2)cc1 +NC(=O)c1cccc(Oc2c(N)cccc2Cl)c1 +COc1ccc(OCc2nc(C#N)c(N3CC(C)OC(C)C3)o2)cc1 +CC(C)c1nc(CCN(C)C(=O)C(c2cccc(F)c2)N(C)C)no1 +O=C(Cc1ccc(F)cc1)Nc1nnc(Cc2ccc(F)cc2)o1 +CC(C)COc1ccc(-c2cn[nH]c(=O)c2CO)cc1 +CC(C)Cn1ccc2cc(NC(=O)C3CC3c3cccnc3)ccc21 +CN(CC1(CO)CCOCC1)C(=O)c1ccccc1-c1ccccc1 +Cn1cc(CNS(=O)(=O)c2ccccc2Br)cn1 +COc1cccc(CCC(=O)c2cccs2)c1OC +N#CC1CCC(OC(=O)c2ccn3cncc3c2)C1 +COc1cccc(-c2n[nH]c3c2C(c2ccc(O)c(C)c2)CC(=O)N3)c1 +CCOC(=O)N1CCc2c(sc3c2C(O)=NC(c2ccc[nH]2)N3)C1 +Cc1ccc(-n2nnc(C(=O)NCC(C)C)c2-c2ccncc2)cc1C +CCCN(CC(=O)NC)C(=O)c1cnc(Cc2ccc(F)cc2)s1 +Cc1noc(C)c1C(=O)OC(C)C(=O)N1CCc2ccccc21 +CCC1CCCCN1C(=O)CSc1nnc(C2CC2)n1CC +CCNC(=O)Nc1ccc(OCCOC)c(F)c1 +CCCNC(=O)N1CC(S(=O)(=O)c2ccc(OC)cc2)C1 +COc1ccc2c(CC(=O)Nc3ccc(OC)c(OC)c3)coc2c1 +COC(=O)CNC(=O)c1nc(C)cc2c(N)cccc12 +CC(Oc1cccc(Cl)c1)c1ccnc2nc(N)nn12 +Cc1cc(C)c2[nH]c(CN3CCC(O)C3)cc(=O)c2c1 +COCC(NC(=O)Cc1c[nH]c2c(C)cccc12)C(N)=O +Oc1ccc2c(c1F)C(c1cnc3ccccc3n1)NCC2 +CCCNC(=O)c1cccc(CNC(=O)N2CCC(C)CC2C)c1 +Cn1nc2n(c1=O)CCN(CC(=O)Nc1ccc(Cl)cc1)C2 +CC(C)(C)NS(=O)(=O)c1ccc(C(=O)NC2CC2)cc1 +CC(c1ccccc1F)S(=O)(=O)c1nnc(C2CC2)n1C +CCS(=O)(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2C)CC1 +CCN(CC)C(=O)C1CCC(=O)N(C)C1c1ccc(F)cc1 +NC(=O)c1cc(NCC2CCCO2)nc2ccccc12 +CCc1noc(C)c1C(=O)Nn1c(C)cc(C)cc1=O +COc1ccc(-c2nn(C)c3c2C(=O)CCC3)cc1 +CC(Oc1ccc(Br)cc1)C(=O)N1CCOC(C)(C)C1 +Cc1cc(C(=O)Nc2ncccc2C)c2ccc(F)cc2n1 +O=C(NCC(=O)N1CCCC1)c1cccc(OCC(F)F)n1 +O=C(NC1CC1)C1CN(Cc2ccnc3ccccc23)CCN1 +Cc1cccc(-c2noc(CCC(=O)Nc3nc(C)cs3)n2)c1 +Cc1cc(N)n(-c2ccc(-c3ccc(C)c(C)c3)nn2)n1 +CC(C)CC(=O)N1CCN(C(=O)c2cc3c(s2)SCC3)CC1 +Cc1cc(NC(=O)N2CCNC(=O)C2)n(Cc2ccccc2)n1 +O=C(Cc1ccccc1)NCC(=O)Nc1cccc(F)c1 +CCN(Cc1ccncc1)C(=O)Nc1ccc(Cl)cc1 +O=C(Nc1nnc(Cc2ccccc2F)s1)c1cc(C2CC2)[nH]n1 +CC(NC(=O)C1CC(=O)Nc2cc(F)ccc21)c1ccncc1 +CN(Cc1cc(Br)cs1)C(=O)C1CC=CCC1 +Cc1noc(C)c1CCC(=O)Nc1ccc2cc[nH]c2c1 +CCCn1ncc(-c2c(C)cc(C)cc2OC)c(CO)c1=O +CCS(=O)(=O)c1ccc(NC(=O)NCc2ccc(C)cc2)cc1 +CCc1c(C)cc(C(=O)N2CCN(c3ncccn3)CC2)c(=O)n1C +CC(C)(C)C(=O)CNC(=O)CN1C(=O)C(C)(C)c2ccccc21 +COC(=O)C(C)CNC(=O)Nc1nnc(C(C)(C)C)s1 +CCc1ccc(OC(=O)Cc2c(C)nc3c(c2C)c(=O)[nH]n3C)cc1 +COc1cccc(C(=O)OCC(=O)NC2CCCCC2)c1OC +CCOc1ccc(CNC(=O)Nc2c(C)cccc2C)cc1OC +COc1cccc2c1cc(C(=O)NCc1ccccc1)n2C +Cc1ccc(-c2nc(C)c(C(=O)NCc3nnc4n3CCC4)s2)o1 +O=C(CCc1ccsc1)Nc1ccnc2ccnn12 +CCOc1ccc(OCc2nc3n(n2)C(=O)CS3)cc1 +O=C(NCc1ccccn1)c1ccc(NC(=O)c2ccccc2)cc1 +COc1cccc(Cl)c1CC(=O)Nc1ccnn1-c1ccncc1 +O=C1CCN(C(=O)c2ccc(C(=O)c3ccccc3)cc2)CC1 +Cc1cc(CNc2ccc[nH]c2=O)ccc1Br +CC(c1ccco1)N(Cc1nc(-c2ccsc2)no1)C1CC1 +N#CCc1nc2cc3c(cc2n1-c1ccccc1)OCCO3 +COC(=O)c1ccc(COc2cccc(NC(=O)C3CC3)c2)o1 +CN1C(=O)C2(CCN(C(=O)c3ccccn3)CC2)c2ccccc21 +Cc1ccc(CNC(=O)c2ccc(C#N)cn2)c(N(C)C)c1 +CCOC(=O)C1(NC(=O)c2nc3nc(C)cc(C)n3n2)CCCC1 +O=S(=O)(c1cccc(Cl)c1)N1CCCCC1 +N#CC1(C(=O)NCc2ccc(-c3nc4ccccc4[nH]3)cc2)CCC1 +O=C(CCNC(=O)Nc1ccccc1)NC1CCCCC1 +CCC(NC(=O)c1ccc(-c2ccccc2)[nH]1)c1ccnn1C +CC(C)Oc1ccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)cc1 +CCN(CC)C(=O)c1ccc(NC(=O)c2cnc3ccccc3n2)cc1 +CCCn1c(C)c(C(=O)NCCNC(C)=O)c2cc(OC)ccc21 +CC(=O)N1CCN(C(=O)Cn2c(-c3cccs3)noc2=O)CC1 +COCCC1NCCc2c(O)ccc(Br)c21 +CCC(CO)(NCc1cc(C#N)ccc1F)c1ccccc1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)C(C)(C)C)CC2)cc1 +NC(=O)CC1CCN(C(=O)c2cc3ccccc3oc2=O)CC1 +CC(=O)NCCNS(=O)(=O)c1ccc2ccccc2c1 +CCN(CC(C)C)S(=O)(=O)c1c(C)cccc1N +Cc1ccc(C(C)Nc2cccc(S(C)(=O)=O)c2)s1 +CN(CCN1CCOCC1)C(=O)Cn1nnc(-c2ccccc2)n1 +Cc1cc(NC(=O)Cc2csc(-c3cccnc3)n2)no1 +CC1(C)Oc2ccc(N)cc2N(CC(=O)N2CCCCC2)C1=O +CCC1(CC)CN(CC(O)CO)c2c(N)cccc2O1 +CC1CN(Cc2nc(=O)c3sccc3[nH]2)C(C)CO1 +O=S1(=O)CCCN1CCOc1ccccc1Cl +Cc1nc2cc3c(cc2n1-c1ccncc1)OCCO3 +CC(C#N)CNC(=O)c1ccc(-c2ccccc2)cc1 +NS(=O)(=O)Cc1ccc(CNC(=O)CC2CCCC2)cc1 +Cn1ccnc1SCc1cccc2c1OCCO2 +Cc1cccn(CCCC(=O)Nc2cccc(N)c2)c1=O +Cc1noc(CCCC(=O)N(C2CC2)C2CCc3ccccc32)n1 +O=C(NCCCc1nc2ccccc2s1)c1scnc1C1CC1 +NC(=O)C(Sc1nccn1Cc1ccccn1)c1ccccc1 +CC(COc1ccc(C(C)(C)C)cc1)NC(=O)NCc1ncn(C)n1 +CC(NS(=O)(=O)c1cc(F)ccc1F)C(=O)NCc1ccco1 +COCCCC(=O)Nc1cc2c(cc1Cl)NC(=O)CO2 +COc1ccc(S(=O)(=O)NCCc2cn(C)c3ncccc23)cc1 +Cc1ccc2ncc(C(=O)Nc3cnn(CC(F)F)c3)n2c1 +CCCC(=O)N1CC2(C)CN(C(=O)CCC)CC(C)(C1)C2=O +Cc1ccc(S(N)(=O)=O)cc1C(=O)Nc1ccncc1 +O=S(=O)(c1c(F)cccc1F)N1CCC(c2cccs2)CC1 +N#Cc1ccccc1Nc1ccc2scnc2c1N +CCOc1cc(C)ccc1NCc1cccc(C(=O)NC)c1 +CCOc1ccc(OC)cc1NC(=O)c1cnc(C2CCCO2)s1 +Cc1nc2cccnc2n1Cc1ccccc1C(F)(F)F +CC(C)N(C)C(=O)c1ccc(C(=O)N(C)C(C)C)cc1 +N#Cc1cnn(-c2ccccc2Br)c1F +COc1ccc2cc(C(=O)Nc3ccc4oc(=O)[nH]c4c3)[nH]c2c1 +Cc1ccccc1-n1ccnc1SCc1cc(=O)c(O)co1 +Cc1nc(CNC(=O)c2sc(-c3ccsc3)nc2C)c(C)s1 +COc1cc(C)c(Cl)cc1S(=O)(=O)N=c1cccc(C)[nH]1 +N#Cc1ccc(NCc2nncn2-c2ccccc2)nc1 +CC(=O)Nc1ccc(NC(=O)CNc2ccc3ccccc3c2)cc1 +CC(=O)NCCCN(C)C(=O)c1cnc(Cc2ccccc2)s1 +Cc1ccc(-n2cnnc2SCC(=O)NC2CC2)cc1 +Cc1ccc(S(=O)(=O)N2CCCC(c3nncn3C)C2)cc1C +COc1cccc(C(O)CCNc2ccccc2C#N)c1 +COC(=O)c1sc(COc2cccc3cccnc23)nc1C +CC(Sc1nnc(-c2ccccc2F)n1N)C(=O)NC1CCCC1 +O=C(Cn1cnc2nc3c(cc2c1=O)CCCC3)NCc1ccco1 +CCc1nnc(NC(=O)CSc2nc(N)cc(N)n2)s1 +CC1(NC(=O)NC2CCC(Oc3ccc(C#N)cn3)CC2)CCC1 +Cc1ccn2c(-c3csc(NCc4ccco4)n3)c(C)nc2c1 +Cn1c(SCC(=O)NC(C)(C#N)C2CC2)nc2sccc2c1=O +O=C(Cn1nc(-c2ccccc2F)ccc1=O)N1CCc2ccccc21 +CCN1CC(C(=O)N2CCC(c3nc4ccccc4[nH]3)CC2)CC1=O +O=C(NCCCN1CCOCC1)Nc1ccc2[nH]ncc2c1 +COc1cc(CN2CCN(c3ccccc3F)CC2)cc(OC)c1 +O=C(Cn1ccc(=O)[nH]c1=O)NCc1cnn(Cc2ccccc2)c1 +O=c1ccnc2sc(NCCc3ccc4c(c3)OCCO4)nn12 +C=CCc1ccccc1OC(=O)c1cc(S(=O)(=O)N(C)C)c(C)o1 +NC(=O)C1CCN(C(=O)C2CCN(c3ccc(Cl)cc3)C2=O)CC1 +Cc1ccc2ncc(C(=O)N(C)c3nccs3)n2c1 +Cc1csc(CNC(=O)c2coc(COc3ccccc3)n2)n1 +Cc1ccc(C(C)NC(=O)c2cc(C(C)C)nc3onc(C)c23)o1 +Cc1ccn(-c2cc(COC(=O)c3cccnc3)ccn2)n1 +COCCCn1ccc(NC(=O)Nc2ccc3c(c2)CC(=O)N3)n1 +Nc1ccc(-c2nc3cccc(F)c3n2CCO)cc1 +O=C(Nc1ccc(F)c(F)c1)c1n[nH]cc1Br +Cc1cc(S(=O)(=O)NC(C)(C)C#N)sc1C +COc1ccc(C)cc1NC(=O)N(Cc1ccccn1)C1CC1 +CCOc1ccc(NC(=O)Nc2cccnc2)cc1 +CCN(CC(O)c1cccc(O)c1)C(=O)c1cnc(C2CC2)[nH]c1=O +CCn1c(CNC(=O)C2CCCO2)nnc1SC +CCCc1cc(NCC(C)n2cc(C)cn2)n2nccc2n1 +Cc1ccccc1OCCSc1ccc(N)nc1 +C=CCNC(=O)CN1CCN(c2ccnc(-c3ccccc3)n2)CC1 +O=C(c1cccs1)N1CCOC2CCCCC21 +COCc1nc(NC(C)C(N)=O)c2c(-c3ccccc3)csc2n1 +COC(=O)c1cc(CN(C)C(=O)CC2CC3CCC2C3)oc1C +CCc1cc(N)cc(C)c1NC(=O)c1ccccc1F +CC(C)CNC(=O)C(C)Nc1ccc(CC#N)cc1 +N#CCCN(C(=O)c1cncc(Br)c1)c1ccccc1F +Cc1nnsc1CNC(=O)c1[nH]c2c(C)ccc(C)c2c1C +CCOc1ccc(Br)cc1NC(=O)c1ccc(F)nc1 +Cc1ccccc1SCC(=O)Nc1ccccc1SCC(N)=O +CCC1CN(C(=O)C2CC(=O)N(CC3CC3)C2)CC1N1CCOCC1 +Cc1cc(NC(=O)CCc2cccc(Br)c2)[nH]n1 +NC(=O)c1ccccc1NC(=O)CNc1ccc(Cl)c(Cl)c1 +OC(CNc1cncc(Br)c1)C1CCOCC1 +COCCN(CC(=O)N(C)C)C(=O)c1cn[nH]c1 +Cc1ccc(F)c(C(=O)N2CCN(C(C)c3ccccc3)CC2)c1F +Nc1c[nH]c(=O)c(C(=O)Nc2cccc(Cl)c2Cl)c1 +Cc1ccc(NC(=O)c2ccc[nH]2)cc1Br +CNC(=O)c1ccccc1OCC(=O)Nc1c(C)cccc1C +CCCc1cc2c(=O)c(-c3csc(C)n3)coc2cc1O +CSc1ncccc1C(=O)Nc1nccs1 +COCCN1CC2(CCCN(C(=O)c3ccco3)C2)C1=O +CCC(C)c1ccccc1N1CC(C(=O)OCC(=O)NC)CC1=O +Cc1ccc(CN(C)C(=O)c2c(-c3ccccc3Cl)noc2C)o1 +CC(NC(=O)NC1CC1)c1ccc(NC(=O)NC2CC2)cc1 +Cc1ccncc1NC(=O)NCC1CCN(c2ccc(F)c(F)c2)C1 +COc1c(Cl)ccc2c1C(CC1CC1)NCC2 +O=C(CSc1ncn[nH]1)Nc1cc(Cl)ccc1O +O=C(NCCc1ccccc1)Nc1nccn(-c2ccccc2)c1=O +CCNc1nc(-c2sc(N(C)C)nc2C2CC2)cs1 +CC(C)(C)N(Cc1ccccc1)C(=O)COc1ccc(C(N)=O)cc1 +C=CCNS(=O)(=O)Cc1ccc(NC(=O)C2CCOCC2)cc1 +O=C1C2CC(CN2Cc2cccc3cccnc23)N1c1ccccc1F +CC(=O)C(Cc1ccccc1)NC(=O)Cn1nnc(-c2ccccc2)n1 +CCN1CC(C(=O)NCc2ccc(SC)cc2)CC1=O +Cc1ccsc1CNC(=O)NCc1ccc2c(c1)OCO2 +Cc1ncc(-c2ccc(NC(=O)C3COCCO3)cc2)o1 +CCc1ccccc1-n1nnc(-c2cccnc2)c1N +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1ccc2c(c1)OCCO2 +O=S(=O)(NCCCOC1CCCC1)c1cc(F)ccc1F +Cn1nc(C(=O)NCCc2ccccn2)c2ccccc2c1=O +Cn1cnc(S(=O)(=O)N2CC3CN(c4ncccn4)CC3C2)c1 +CCOCCn1nc(C)cc1C(=O)N1CC2CC=CCC2C1 +CC(C(=O)N(C)CC(=O)Nc1ccccn1)n1cccn1 +COC(=O)CCN(C)S(=O)(=O)c1ccc(=O)[nH]c1 +CC(O)CNC(=O)c1csc(-c2ccsc2)n1 +CC(=O)Nc1ccc(C(=O)NC(C)Cc2ccc(O)cc2)cc1 +CNS(=O)(=O)c1ccc(C(=O)NC(C)c2ccccc2)o1 +CC(C)C(NC(N)=O)C(=O)NCc1cc(Br)ccc1F +FC(F)(F)c1ccnc(Nc2ccn(-c3ccccc3)n2)n1 +CCCNC(=O)CCC(=O)N1CC(C)Oc2ccc(C)cc21 +COC(=O)C(NC(=O)c1ncn(-c2ccccc2)n1)c1ccccc1 +COc1cccc(C(=O)OCC(=O)N(C)c2ccccc2)c1 +C=CCn1c2c(ccc1=O)CC(NC(=O)N1CCCC1)CC2 +O=C(Nc1ccccc1OCCc1ccccn1)NC1CCOCC1 +CCn1cnnc1Cn1cccc(C(F)(F)F)c1=O +CN(CC1(CO)CCC1)C(=O)C1CC(=O)N(Cc2ccncc2)C1 +CCNc1ccc(Cl)cc1C(=O)NC1CCCC1 +CN(C1CCc2ccccc21)S(=O)(=O)c1ccc(F)cc1 +CC(C)n1ccc2c(NC(=O)c3cc(=O)[nH]c4ccccc34)cccc21 +COCc1nsc(NC(=O)c2c[nH]nc2-c2ccccc2F)n1 +CCC(=O)Nc1cc(-c2cc(Cl)ccc2OC)n[nH]1 +Nc1cccc2ccnc(C(=O)NCCc3ccccc3)c12 +CCCC(=O)NCCN1CCN(c2nc3c(C)cccc3s2)CC1 +O=C(CC1CCCC1)NC1CCCc2ccccc21 +COc1ccc(OC)c(CC(=O)Nc2cccc(SC)c2)c1 +OCCCn1c(C(F)(F)F)nc2cc3c(cc21)OCO3 +Cc1cc(NC(=O)c2ccc(Cl)cc2F)[nH]n1 +CC(C)CNc1ncnc2c1cnn2-c1ccc(F)cc1 +Cc1ccc(CNC(=O)c2csc3c2CCCO3)o1 +CN(CC(=O)OCc1ccc(F)cc1)S(=O)(=O)c1cccnc1 +Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NC(C)c1ccccc1 +CSc1nnc(SCCCc2cnn(C)c2)s1 +Cc1c(C(=O)N2CC(O)C2)c(=O)oc2ccccc12 +Cc1ccccc1N1CCN(C(=O)C(O)C2CCCCC2)CC1=O +O=C(NC1=CC2N=CC=C2C=C1)c1ccc(F)cc1-n1cnnn1 +CN(CCOCC1CC1)C(=O)Nc1cnn(-c2ccccc2)c1 +Cc1csc(C(OC(=O)c2ccc(F)cc2F)C(F)(F)F)n1 +CC(Oc1ccc(C#N)cc1)C(=O)NCC(C)N1CCOCC1 +Cc1csc(N(C(=O)CCn2ccccc2=O)c2ccccc2)n1 +c1ccc(OC2CCCC2Nc2nccn3cnnc23)cc1 +CCOC(=O)CN(CC)C(=O)c1ccc(NC(N)=O)cc1 +O=C(Cc1csc(-c2cccc(F)c2)n1)NCc1ccncc1 +Cc1cc(C)c(C(=O)Nc2cc(N)ccc2C)c(C)c1 +COc1ccccc1C1CC(c2ccc(F)cc2)=Nc2ncnn21 +CC(=O)c1ccc(C)n(CCOc2cccc(N)c2)c1=O +CCC1=NC2(CCC3CN(S(=O)(=O)CC)CC32)C(=O)N1CC +Cc1nc(N2CCOCC2)ncc1C(=O)Nc1ccc(F)cc1 +CC1CN(C(=O)CSc2nnc(-c3cccnc3)n2C)CC(C)O1 +CCC(C)(CC(=O)OC)NC(=O)c1cnn(-c2ccncc2)c1C +COCCCNc1ncc(-c2ccsc2)c(-c2nccs2)n1 +O=C(CCNC(=O)c1ccoc1)Nc1cccc(Cn2cccn2)c1 +COC(=O)CCC(=O)N=c1[nH]c2ccccc2n1C1CCCC1 +CCCOC(=O)C1=C(C)NC(=O)NC1c1ccc(O)c(OCC)c1 +CC(C)NC(=O)N1CCC2(CC(=O)N(c3ccccn3)C2)C1 +C#CCN1CCN(C(=O)NCc2ccccc2N2CCOCC2)CC1 +CC1(C)C2CCC1(C(=O)N1CCCCC1)c1nc(C#N)c(C#N)nc12 +Cc1nnc(SC(C(=O)Nc2ccccc2F)C(C)C)s1 +O=C(c1cc(Cl)c[nH]1)N1CCCC(C(=O)N2CCOCC2)C1 +Cc1ccc(CNC(=O)CCS(=O)(=O)c2ccccc2)cc1 +CCOc1ccccc1N1CC(C(=O)Nc2ncccc2C)CC1=O +COC(=O)CN1Cc2cccc(Br)c2CC1C +COc1cc(CN(C)C(=O)CC(C)(C)C)c(SC)cc1OC +CCN(CC)C(=O)CSc1nc2c(c(=O)[nH]1)CCC2 +CN(CCCNC(=O)NCC(=O)N1CCCC1)c1ccccc1F +CC(C)CC(NC(=O)c1cccc(C#N)c1)c1ccccc1 +CC(C)c1nnc2n1CCN(C(=O)c1ccc3cc[nH]c3c1)C2 +Nc1ccc2c(c1)C(O)n1nc(-c3ccccc3)nc1S2 +CCOCCNC(=O)N1CCc2cc(F)ccc2C1 +CC(C)Oc1ccccc1NC(=O)N1CCN(C(=O)N(C)C)CC1 +O=C(Cn1[nH]c(=O)ccc1=O)Nc1nnc(C2CC2)s1 +COc1cccc2[nH]c(C(=O)NCC(=O)Nc3nc(C)cs3)cc12 +Cn1c(C(=O)Nc2ccc3[nH]ccc3c2)cc2cc(F)ccc21 +O=S(=O)(NC1CCCC1)c1cnn(-c2ccccn2)c1 +CC(NC(=O)COc1ccccc1O)c1cccc(C(F)(F)F)c1 +Cc1ccccc1OCc1nc(C(=O)NC2CC2)cs1 +COc1ccc(-c2cc(C(C)=O)c(C)n2C)c(C)c1C +CC(=O)N1CCN(C(=O)C2COCC(=O)N2Cc2ccccc2)CC1 +O=C(CCc1ccccc1O)NC1CCCN(c2ncccn2)C1 +CCc1c(C)[nH]c2ccc(N(CC)CC)cc2c1=O +Cc1c(NC(=O)c2cccc(OC3CCCC3)c2)cccc1C(N)=O +O=C(CCOCC1CCCO1)Nc1nnc(C(F)(F)F)s1 +COC(=O)CCSc1nc2ccccc2nc1C +COCc1cc(CNC(=O)C2CCN(C(=O)C3CCCC3)CC2)n[nH]1 +Cn1nccc1C(=O)N1CCN(c2ccc(Cl)cc2)CC1 +CN(C)c1ncccc1C(=O)N1CCN(CCc2ccccc2)CC1 +Cc1nc(-c2cnn3ccccc23)sc1CCO +CCN(CC1CCOCC1)C(=O)CCc1nc2ccccc2[nH]c1=O +Cc1cc(NC(=O)NC(C)c2cccc(Br)c2)no1 +O=c1cc(-c2ccccc2F)[nH]c2cc3c(cc12)OCO3 +CCn1c(SCc2nnc(C)o2)nnc1-c1ccccc1C +COCCCNC(=O)c1ccc(N(C)C)c(F)c1 +Cc1cccc(C)c1NC(=O)c1c(-c2ccc(F)cc2F)noc1C +CN(Cc1ccc(Br)cc1)C(=O)NCc1cnn(C)c1 +Cc1nn(CC(C)C)c(C)c1CC(=O)N(C)CCc1ccccc1O +CC(C)c1ccn(-c2ccc(N)c(C(F)(F)F)c2)n1 +COc1ccc(NC(=O)COc2ccccc2O)cc1Cl +O=C(C1CCOC1)N1CCC(Oc2cccc(Cl)c2)C1 +CCCOC(=O)CN1C(=O)CNc2cc(Cl)ccc21 +FC(F)c1nnc(N2CCCC(COc3ccccc3)C2)s1 +CNC(=O)c1cccc(CNc2ccc(C(=O)NC)c(Cl)c2)c1 +CC(=O)Nc1cccc(C(O)CCN2CCOCC2)c1 +CCNC(=O)N(Cc1cscn1)c1ccccc1 +CCc1nc(CC(=O)NCCC(=O)N2CC(C)OC(C)C2)cs1 +COc1cc(C(=O)NCCc2ccccc2)sc1S(N)(=O)=O +COc1ccc(-n2nnc(C(=O)NC3CC3)n2)cc1 +CCOc1cc(F)ccc1NCc1cnnn1C +CCOC(=O)CN(CC)S(=O)(=O)c1cccc(Cl)c1C +COc1cc(F)c(S(=O)(=O)NCc2ccccn2)cc1OC +Cc1cc(CS(=O)(=O)N(CCO)C2CCCC2)no1 +CCOC(=O)c1cnn(-c2ccc(OC)cc2)c1C +CC(=O)NCc1ccc(C(=O)Nc2ccccc2-n2ccnc2)cc1 +O=C(Cc1ccc2c(c1)OCCO2)NC1CCCCC1 +Cc1nn(C)c(C)c1S(=O)(=O)NCc1ncoc1C +CCc1ccc(S(=O)(=O)NCc2sccc2C)s1 +Cc1cc(C)c(-c2nc(CC(N)=O)nn2-c2ccc(F)cc2)cn1 +Cn1cnc(S(=O)(=O)NC2CCc3c(ccc(=O)n3C)C2)c1 +Cc1ccc(-n2cc(C(=O)NCC3CCCO3)nn2)cc1C +CCCN(C)S(=O)(=O)Nc1cccc(C)c1C(=O)N1CCCC1 +Cc1cc(C)nc(-n2nc(C)c(CC(=O)N(C)C)c2C)n1 +Cc1ccc(CNC(=O)C(C)NC(N)=O)c(Oc2ccccc2)c1 +Cc1nn(C)c(Oc2cccnc2)c1CNc1cnc2ccccc2c1 +O=C(Nc1ccc2c(c1)OCO2)c1n[nH]c2c1CCCCC2 +NC(=O)CC1CCN(C(=O)c2csc(-c3ncccn3)n2)CC1 +CC(C)S(=O)(=O)c1ccc(COc2ccc(CO)cc2)cc1 +COc1cccc(N2CCN(C(=O)c3c(F)cccc3F)CC2)c1 +COc1ccc(Cn2cc(C(=O)NC(C)(C)CO)cn2)cc1 +COc1ccccc1-c1n[nH]c(C)c1Br +O=C(NC(CCCO)c1ccccc1)c1ccc(Br)cn1 +Cn1nnnc1-c1cccc(NC(=O)C(C)(C)c2ccccc2)c1 +CNC(=O)c1ccc(C2NC(=O)c3ccccc3N2)cc1 +Cc1cc(CSc2ncccc2C(=O)Nc2ccccc2)no1 +CC(=O)c1ccc(NCc2nc(-c3ccsc3)no2)cc1 +CCCOc1cc(C)ccc1NCc1cc(C)on1 +COc1ccc(C(=O)NCc2c(C)nn(Cc3ccccc3)c2C)cc1 +COCc1cc(Cn2cnc3c(C)cc(C)cc3c2=O)n[nH]1 +CCn1cnnc1CNC(=O)c1ccc(-c2ccccc2)[nH]c1=O +O=C(Nc1cccc(Oc2cccnn2)c1)C1CC2C=CC1C2 +CC(=O)NC(CC(=O)Nc1ccc(C)cn1)c1ccccc1 +COc1ccc(C(CC(=O)NCc2cccnc2)c2ccccc2)cc1 +CC(=O)N1CCN(C(=O)COc2ccc3ccc(=O)oc3c2)CC1 +Cc1nn(C)cc1CN(C)C(=O)Nc1cccc(F)c1 +CC(C)OCc1cccc(S(=O)(=O)Nc2cccc(C(N)=O)c2)c1 +O=C(Cn1cnnn1)NCCOc1ccc2c(c1)CCC2 +N#Cc1ccc(OCCCNc2ccc(C(N)=O)cc2)cc1 +C#CCOC(=O)C1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1 +Cc1ccn(-c2ccc(NCCn3c(C)nc4ccccc43)nn2)n1 +CC(C)c1nncn1CCNC(=O)c1cccc(-n2cccn2)c1 +CC(=O)NCCNC(=O)Nc1ccc(Sc2ccccc2)cc1C +CCc1onc(C)c1NC(=O)c1cc(-c2ccncc2)on1 +O=c1c2ccccc2c(-c2ccccc2)nn1CCO +COc1cccc(COC(C)C(=O)Oc2ccc3cn[nH]c3c2)c1 +Cn1c(C(=O)NCCCN2CCCC2=O)nc2ccccc2c1=O +Cc1cccc(C)c1NC(=O)NCc1nc2ccccc2s1 +COc1cccc(C(=O)OCCN2CCCC2=O)c1F +Cc1n[nH]c(SCC(=O)N(CCC#N)Cc2ccco2)n1 +Cc1cc(NC(=O)CNc2c(C)cccc2C(=O)N2CCCC2)no1 +Cc1cnn(CCCNc2ccc(-c3nc(C)cc(=O)[nH]3)cn2)c1 +O=C(NCCCO)NCC1CN2CCCCC2CO1 +COC(=O)Cn1c(-c2cccc(F)c2)nc2c(N)cccc21 +COC(=O)Nc1nc(CC(=O)NC2CCCC2)cs1 +Cc1cccc(C)c1NC(=O)c1cnccc1C(F)(F)F +OCCn1ncc2c1CCCC2Nc1nc2ccccc2o1 +CC(C)C(NC(=O)Cc1ccccc1)C(=O)Nc1nccs1 +Fc1cccc(CN2CCC(c3nc(-c4ccncc4)no3)C2)c1F +Cc1cc(CN(C)C(=O)Nc2ccc(Cl)cc2Cl)no1 +CC(OCC1CC1)C(=O)N1CCC(NC(=O)CC2CCCC2)CC1 +CC(C)c1cc(Br)ccc1NC(=O)C1CCC(=O)N1 +CC1CCc2c(C(=O)Nc3ccncc3)csc2C1 +O=C(Cc1ccc(C(F)(F)F)cc1)NCc1nnc2n1CCC2 +CCC(C)NC(=O)c1nn(-c2ccc(C)cc2)c(OC)cc1=O +CCN(Cc1c[nH]nc1-c1cccs1)CC(C)C#N +CC1CNc2cc(C(=O)CN3CCOCC3)ccc2O1 +Cc1cccc(N2CCN(Cc3nnc(C)o3)CC2)c1 +Cc1ccccc1COC1CCN(C(=O)COCC2CCOC2)CC1 +Cc1noc(C)c1COc1ccc(C(=O)NC(C)(C)C)cc1 +Cc1nc(NC(=O)N2CCCC(c3nc4ccccc4[nH]3)C2)nn1C +Cc1c(C(=O)NC2(c3ccc(Br)cc3)CCC2)cnn1C +Cc1ccc(F)c(NC(=O)Cc2ccc(C)nc2)c1 +CC(Sc1nnc(C2CC2)n1C1CC1)C(=O)NC1CCCCC1C +COc1ccc(NC(=O)c2ccc(C(=O)N(C)C)cc2)cc1 +Cc1cc2c(=O)n(CC(=O)NC(C)c3ccco3)cnc2s1 +CCOC(=O)Nc1ccc(C(=O)N(C)Cc2cnn(C)c2)cc1 +COC(=O)CNC(=O)CC1(n2cccc2)CCCCC1 +Cc1nc2c(-c3ccc(F)cc3)csc2c(=O)[nH]1 +Cc1[nH]c2ccnn2c(=O)c1CC(=O)NC(C)C1CCCCC1 +N#Cc1ccc(C(F)(F)F)nc1NCCCc1nnc2ccccn12 +Cc1nnc(SC(C(=O)NC(C)c2ccccc2)C(C)C)s1 +CN(C)C(=O)CN1CCN(c2c(N)cccc2Cl)CC1 +COC(=O)Nc1ccc(NC(=O)N2CC(C)CC(C)C2)cc1 +Cc1ccnn1CC(=O)N1CCCC(OCc2ccccn2)C1 +C=CCCCN(C)C(=O)c1cnc(OCC)c(Cl)c1 +CCN1C(=O)NC(c2ccccn2)C(C(=O)OC)=C1C(C)C +CC(C)c1ccc(N2CCN(CC(=O)N(C)C)C2=O)cc1 +COCCC(C)C(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +O=C(Cn1ccc2ccccc21)Nc1ccc(-c2csnn2)cc1 +CCC(O)CN1CCN(C(=O)c2csc(S(N)(=O)=O)c2)CC1 +Cc1cnc(C(=O)OCC(=O)Nc2ccc(C)c(F)c2)cn1 +C#CCN(Cc1ccc(F)cc1)C(=O)Nc1nccs1 +N#CCc1c(-c2cccnc2)nc2scc(-c3cccs3)n12 +Cc1ccccc1N1CCN(CC(=O)c2ccc3c(c2)OCO3)CC1 +CC(=O)c1cccc(NC(=O)CCc2nc3ccccc3s2)c1 +CC(NC(=O)C1CCN(c2cnccn2)CC1)C(C)c1ccccc1 +COc1ccccc1CN(C)C(=O)c1cnc(C)cn1 +Cc1cc2n(n1)CCCN2C(=O)CCC(=O)NCc1ccc(C)o1 +Cc1cc(C(=O)Nc2cc(C)nn2Cc2ccccc2)[nH]n1 +Cc1cc(C)c(NC(=O)C(C)n2nc(C)ccc2=O)c(C)c1 +CC(NC(=O)COC(=O)c1ccc(-c2ccccc2)[nH]c1=O)C1CC1 +CCn1cc(Cl)c(C(=O)Nc2cc(C)nn2C2CCCC2)n1 +Cc1ccc(C(C)NC(=O)N2CCCC(c3nncn3C)C2)o1 +CC(C)CCNC(=O)C(C)Sc1nnc(C2CC2)n1C +CC(C)C(C)NC(=O)CN(C)S(=O)(=O)c1cccs1 +CCc1noc(CC)c1CC(=O)N(C)CCc1ccc(F)cc1 +CC(NCCc1ccccc1F)c1cccc(O)c1 +CN(C)c1nc(N)nc(CN(Cc2ccsc2)C2CC2)n1 +COc1cc(CNC(=O)c2ccn(C)c(=O)c2)ccn1 +COc1ccc(CCn2c(CO)nc3ccc(Cl)cc32)cc1OC +Cc1oncc1NC(=O)c1cn(C)nc1C(C)(C)C +CCc1cc(=O)n(CC(=O)NC(C)C)c(-c2cccc(Cl)c2)n1 +O=C(NCCC(=O)N(Cc1ccc(F)cc1)C1CC1)c1ccsc1 +COC(=O)c1cc(C)sc1NCC(C)C(=O)OC +Cc1csc(S(=O)(=O)Cc2ccccc2Cl)n1 +c1cncc(NCCNc2nccc(C3CCCC3)n2)c1 +Cc1cccc(C(=O)Nc2ccccc2N(C)S(C)(=O)=O)c1F +CCCCOC(C)C(=O)N1CCN(C(=O)Nc2cccc(C)c2)CC1 +CC(=O)c1ccc(S(=O)(=O)Oc2cccc(Cl)c2)cc1 +O=C(NCc1ccc2c(c1)OCCO2)c1ccccc1Br +Cc1ccc(NC(=O)c2cc(F)cc(F)c2)cc1N +Cn1cc(NC(=O)NCc2ccc(OCC(F)(F)F)cc2)cn1 +CCOC(=O)C1(NC(=O)Cc2csc(CC)n2)CCCC1 +Nc1nc(CCC(=O)N2CCC(C(=O)N3CCCC3)CC2)n[nH]1 +CN(C(=O)Cn1cnc2c(Cl)cc(Cl)cc2c1=O)C1CC1 +Cc1nc(C)c(C(=O)N2CCC(Oc3ncccn3)CC2)s1 +Cc1c(OCC(=O)OC(C)C)ccc2c(=O)c(Cl)coc12 +CCS(=O)(=O)N1CC(c2nc(-c3cnccn3)no2)C1 +CC(NC(=O)COCC1CCCO1)c1ccc2c(c1)CCC(=O)N2 +CC(NC(=O)c1ccccc1)C(=O)NCC1(c2ccccc2)CCC1 +COc1ccccc1OCC(=O)N(C)Cc1ccc(F)cc1F +O=c1c2ccsc2ncn1Cc1ncc(-c2ccc(F)cc2)o1 +COc1cc(OC)c(CNCC(=O)N(C)C)c(OC)c1 +COc1ccc(C2CN(c3ccc(Cl)cn3)CC2NC(C)=O)cc1 +Cc1ccc(C(=O)NCc2ccccc2Cn2cccn2)c(C)c1 +COc1ccc(C)cc1NCC(=O)Nc1ccnn1C(C)C +Cc1cccn2cc(-c3nc(CCN4CCCC4=O)no3)nc12 +CCc1ccc(CNC(=O)Cn2ncc(N3CCCC3)cc2=O)nc1 +COc1ccc(Cl)cc1CNc1c(C)cccc1C(N)=O +C#CCN(C(=O)c1cc(C(C)C)[nH]n1)C1CCCCC1 +Nc1ccccc1OCCCn1c(C2CC2)nc2ccccc21 +CCOC(=O)c1ccc(NC(=O)c2ccc(-n3cnnn3)cc2)cc1 +Cc1cc(SCC(=O)Nc2cc(Cl)ccc2C)nc(C)n1 +C#CCNC(=O)NCc1cccc(NC(=O)C2CCC2)c1 +CC(C)C(=O)Nc1ccc(SCC(=O)Nc2ccccc2F)nn1 +COc1ccc(-n2cc(CNC(=O)Cn3cnnn3)nn2)cc1 +COc1cc(C)cc(CNC(=O)N2CCC(n3cccn3)CC2)c1 +Cc1cc(F)cc(NC(=O)c2cnn(-c3ccncc3)c2C)c1 +Cn1cccc1CN(Cc1cccs1)C(=O)c1ccncc1 +O=C(NCc1ccc(F)cc1)c1cccc(Cl)c1 +CCN(C(=O)CNc1cccc(C(=O)NC)c1)c1ccccc1 +CCc1nnc(NC(=O)c2cc3c(s2)CCCC3)s1 +COc1cc(NC(=O)CNc2nc(C)cc(C)n2)cc(OC)c1OC +CCCn1ccnc1SCC(=O)NCC1COc2ccccc2O1 +CCC(C)N(CCOC)c1ccc(N)c(OC)n1 +Cc1nc2ccc(NC(=O)Cn3c(C)c(C)sc3=O)cc2o1 +Cc1nc2oc(C(=O)N3CCCC3)c(N)c2c2c1CCCC2 +Cc1cc(C)n(Cc2cccc(NC(C)c3nnc(C)o3)c2)n1 +COCC(=O)N1CCc2c(c(COC)nn2CC2CC2)C1 +CCc1ccc(C(=O)NCc2ccccc2Cn2cccn2)cc1 +O=C(NCCn1cc(Cl)cn1)C1CCN(C(=O)C2CC2)CC1 +CC(=O)c1cccc(NC(=O)CN2CCOC3CCCCC32)c1 +COc1ccc(CNC(=O)CNc2c(C)cc(C)cc2C)cc1OC +COc1cc(C)sc1C(=O)NCc1ccc(-n2cncn2)cc1 +N#CCCC(C#N)COc1ccc(NC(=O)c2cccs2)cc1 +COc1ccc(OC)c(S(=O)(=O)Nc2ccccc2C)c1 +COc1ccc(NC(=O)c2c(OC)cccc2OC)cc1 +Cc1cccc(N2CC(C(=O)Nc3nc4ccccc4[nH]3)CC2=O)c1C +CCOc1ccc(C(O)C(CN2CCOCC2)c2ccccc2)cc1 +CCOC(=O)C1CCN(C(=O)c2cc3c(C)cc(F)cc3[nH]2)CC1 +CCOCC1CCCN(S(=O)(=O)N2CCCCC2)C1 +COCCCn1cnnc1C(C)Nc1ncnc2nc(C)cc(C)c12 +CCOC(=O)CNC(=O)N1CCCN(S(C)(=O)=O)CC1 +CCOC(=O)c1coc(N2CCC(O)(c3ccc(C)cn3)CC2)n1 +COc1ccc2ncnc(N3CCCC(C)C3)c2c1 +Cc1cc(NCc2cccnc2)cc(=O)n1Cc1ccco1 +Cc1ccc(S(=O)(=O)CCC(=O)Nc2ccccc2C(N)=O)cc1 +CCCC(=O)Nc1ccc(NC(=O)c2cccnc2)cc1 +CC(C)Cn1nccc1NC(=O)c1ccc(OC(C)C)nc1 +COc1ccc(CNS(=O)(=O)c2ccc(Cl)cc2C)cn1 +O=c1nc(SCc2cc(F)cc(F)c2)c2c([nH]1)CCC2 +CCN(Cc1nc2c(cnn2C)c(=O)[nH]1)Cc1ccco1 +O=C(CCNS(=O)(=O)c1ccc(F)c(F)c1)N1CCC(O)C1 +CCN(CCc1ccccc1)C(=O)CSc1nc(C)n[nH]1 +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)NCC1CCCC1 +CC(=Cc1ccccc1)CN1CCOC(c2nccs2)C1 +CCc1nn(CC(=O)OC)c(=O)c2cc3occc3n12 +COc1ccc2c(CC(=O)Nc3ccc(CC#N)cc3)cc(=O)oc2c1 +COCCN1CC(C(=O)NCc2cc3ccccc3o2)CC1=O +CC(OCCO)C(=O)Nc1ccc(Cl)c(N)c1 +Cc1ccc(NC(=O)C2CC2)cc1NC(=O)N1CCC(CO)CC1 +CCNC(=O)COc1cccc(NC(=O)NC2CCCC2)c1 +NC(=O)c1ccc(CNC(CC(F)(F)F)c2ccccc2)cc1 +Cc1cc(C(C)NC(=O)COc2ccccc2F)c(C)s1 +CCCNc1nc(NCc2cccnc2)nc(N2CCOCC2)n1 +CC(OCC1CC1)C(=O)N1CCN(C(=O)Cc2ccccn2)CC1 +O=C1CCc2ccccc2N1CCC(=O)N(CC(F)F)C1CC1 +O=C(COn1nnc2ccccc21)NCCc1ccc(Cl)cc1 +CCN(CC)C(=O)CCc1cc2cc(OC)ccc2[nH]c1=O +Cc1ccc(Cl)c(OCc2nc(C)c(CO)s2)c1 +Cc1cnc(C2NCCc3c2ccc(C)c3Cl)cn1 +NC(=O)COC(=O)C(O)(c1ccccc1)c1ccccc1 +O=C(NC1CCCc2[nH]c(=O)ccc21)c1cc2ccccc2o1 +Cc1oc2c(c1C(=O)NCc1ccccc1)CCCC2 +COCC(C)NC(=O)Cc1csc(-c2cccc(F)c2)n1 +CN(C)C(=O)CN(C)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +N#CC(CC(=O)N1CCCC1)c1c(Cl)cccc1Cl +COc1ccccc1CNC(=O)Nc1ccc(C(=O)NC(C)C)cc1 +Cn1c(CN(Cc2ccccc2)Cc2ccco2)nnc1C1CC1 +C=CCCCN(C)C(=O)Nc1ccc(F)c(F)c1F +COc1cccc(C(=O)N=c2[nH]c3ccccc3[nH]2)c1F +Nn1c(-c2ccccc2)nc2cc3c(cc21)OCCO3 +CC(NC(=O)Nc1cn[nH]c1)C(=O)NCc1ccco1 +CCCC(C)NC(=O)c1cc(OC)c(OC)c(OC)c1 +CCCOc1ccc(Cl)c2c1CCNC2C(O)CO +O=C(CCc1ccco1)Nc1ccc2nccnc2c1 +CCN(C(=O)NC1CCN(C(=O)OC)CC1)C1CCCCC1 +CC(=O)Nc1ccc(S(=O)(=O)NCc2sccc2Cl)cc1 +CC(=O)NC(C)(C)c1noc(Cc2ccc3ccccc3c2)n1 +O=C(NCc1cccs1)NC1CCN(c2nccs2)CC1 +CN(C)C(CNC(=O)C1CC=CCC1)c1cccs1 +CNC(=O)CNS(=O)(=O)c1cccc(Br)c1 +CCOc1cc(C2NC(=O)NC(CC)=C2C(=O)OC)ccc1OC +CCOC(=O)c1cnc2nc(C)ccc2c1Nc1ccc(Cl)cn1 +N#Cc1ccc(C(=O)N(CCCO)Cc2cccc(Cl)c2)nc1 +Cc1cccc(Cl)c1NC(=O)N1CCCC1C(=O)NC1CC1 +COc1ccc(CN2CCOC(C#N)C2)c(OC(C)C)c1 +O=C(COc1ccc2c(c1)CCC2)NCc1cscn1 +CC(C)(C)OC(=O)N1CCc2ccc(NC(=O)C3CCCO3)cc2C1 +COCc1ccc(C(=O)N2CCN(C(=O)c3cc(C)oc3C)CC2)o1 +CCC(C)n1nccc1NC(=O)c1cnn(Cc2ccccc2)c1 +Cc1nc(CN(C)C(=O)c2occc2-c2ccccc2)no1 +CCOC(=O)c1c(C)nn(-c2ccc(NC(=O)C(C)(C)C)cc2)c1C +CC(NC(=O)c1n[nH]c(=O)[nH]1)C(=O)NC1CCCC1 +Cn1cccc1-c1cc(C(=O)NCc2nnc3n2CCC3)[nH]n1 +CCc1ccc(NC(=O)Nc2ccc3[nH]c(=O)oc3c2)cc1 +NC(=O)c1cc(N)n(Cc2cnn(-c3ccccc3)c2)n1 +CC(C)CCC(C)(O)CNC(=O)NC1CCCC1C +O=C(Nc1nccs1)c1cc(=O)c(OCc2ccccc2F)co1 +Nc1c(F)cccc1Sc1nnnn1C1CC1 +O=C(CSc1c[nH]c2ccccc12)NCc1cnn2ccccc12 +CCOc1cc(F)ccc1NC(=O)c1cn(C)nc1-c1cccs1 +CC(O)CNC(=O)C1CCCN1C(=O)c1ccccc1OC(F)F +COc1cc2c(cc1Cl)C(c1cccc(O)c1)NCC2 +Cc1nnnn1-c1cccc(C(=O)NCc2ccccc2)c1 +COC(=O)c1cc(NC(=O)c2ccccn2)ccc1F +O=C(c1ccsc1)N1CCC(OCc2ccccc2F)CC1 +NC(=O)c1csc(C(=O)N2CCCCCC2c2ccncc2)c1 +O=C(OCCN1CCCC1=O)C1CCN(c2ncccn2)CC1 +CC(C)(C)C(C#N)NC(=O)c1cccc(SCC#N)c1 +Cc1ccccc1OCC(=O)NCC1CCN(S(C)(=O)=O)CC1 +O=C(Nc1nccs1)c1c(-n2cnnn2)sc2c1CCC2 +CCC(NC(=O)N1CC(C)OC(C)C1)c1ccc2c(c1)OCCO2 +COCC(C)NC(=O)Nc1cscc1C(=O)OC +COc1cc(CN(C)C(=O)c2cccc(-n3cccn3)c2)ccc1O +O=C(CC1CC1)N1CCCn2nnc(Cn3cccc3)c2C1 +Cc1cc(C)c2c(-n3cccc3)c(C(=O)N3CCOCC3)sc2n1 +Cc1nn(C)c(C)c1NC(=O)CN1CCc2sccc2C1 +CC1C(=O)N(c2cccc(F)c2)CCN1C(=O)C1CCCC1 +Cc1nc(Cn2nnc(CN(C)C(=O)c3ccccc3)n2)sc1C +CCN1CC2(CCC1=O)CCN(C(=O)C(NC)c1ccccc1)CC2 +Cc1cc(NC(=O)c2cccc(S(C)(=O)=O)c2)c2ncccc2c1 +COc1ccc(C(=O)c2cccc(N)c2)cc1C(C)C +Cc1cc(C(=O)NC2CCCc3nc(-c4cccnc4)ncc32)n[nH]1 +CCCn1c(SC(C)c2nnnn2-c2ccccc2)n[nH]c1=O +O=C(NCCc1n[nH]c(=O)[nH]1)C1CCC(=O)N(C2CCCCCC2)C1 +CCCC(=O)N1CCC(C(=O)NCC(C)c2cccs2)CC1 +CCOc1cccc2c1CCNC2c1sc(C)nc1C +COCCNC(=O)CN1c2cccc3cccc(c23)S1(=O)=O +O=C(c1cccc(OCC(F)F)n1)N1CCN(c2ccccc2)CC1 +CCNc1ccccc1S(=O)(=O)NCC1CCOC1 +Cc1nc(N2CCN(Cc3ccccc3F)CC2)c2cnn(C)c2n1 +Cc1cnn(CCC(=O)N(C)Cc2ccc(F)cc2)c1 +COc1ccc(C(NS(=O)(=O)c2ccccc2C#N)C(C)C)cc1 +CCn1cc2c(n1)C(COC)CN(Cc1ccc(OC)cc1)C2 +COCC(NC(=O)c1c(C)nc2ccc(C)cn12)c1ccnn1C +COc1cc(C(C)Nc2nnc(C)c(C)c2C#N)ccc1OCCO +O=C1CCN(S(=O)(=O)C2CCCCC2)CCN1 +CCOc1cc(C#N)ccc1OS(=O)(=O)c1ccccc1COC +CCC(C)NC(=O)C(C)NC(=O)c1sc(C)cc1OC +CCn1cc(NC(=O)C2(c3ccc(Cl)cc3)CCOCC2)cn1 +Cc1nn(-c2ccccc2)nc1C(=O)Oc1cncc(Cl)c1 +C=CCNC(=O)NCC(=O)N1CCC(Cc2ccccc2)CC1 +CCOCCOCC(=O)Nc1cccc(Br)c1 +CN(Cc1csc(-c2cccs2)n1)C(=O)c1cnn(C)c1 +O=C(NCCCn1cccn1)c1ccc(O)c(Cl)c1 +CC(C)C(NC(=O)C12CC3CC(CC(C3)C1)C2)C(=O)NC1CC1 +COc1cc2c(cc1OC)CN(C(=O)CN(C)CCC#N)CC2 +O=C(Cn1ccc(=O)[nH]c1=O)NC(c1cc2ccccc2o1)C1CC1 +CCOc1ncccc1CNC(=O)NC(C)c1nncn1C +O=C(NCc1cccc(F)c1)c1nc(-c2ccccn2)no1 +N#Cc1ccc(OS(=O)(=O)c2sccc2Br)cc1 +CCOc1cc(F)ccc1NC(=O)Cn1ncc(=O)c2ccccc21 +CNC(=O)c1ccc(NC(=O)CCNC(=O)c2ccccc2)cc1 +Cc1cccc(NCC(O)c2ccc3c(c2)OCO3)c1 +COc1cc(C(=O)CN2CCOCC2)ccc1Oc1ccccc1 +O=C(Nc1ccc2c(c1)OCO2)c1snnc1-c1ccccc1 +Cn1cnc(CNS(=O)(=O)c2ccc(F)cc2)n1 +CCc1ccc(OC)c(S(=O)(=O)NCc2ccccc2)c1 +Cc1c(NC(C)C(C)C)cccc1C(=O)OCC(N)=O +N#Cc1ccc(NC(=O)COC(=O)CNC(=O)C2CCCCC2)cc1 +Cn1cc(N2CCCC(Sc3cn[nH]n3)C2=O)cn1 +Cn1c(N)c(C(=O)CSc2n[nH]c(=O)[nH]c2=O)c(=O)n(C)c1=O +CC(=O)N(C)c1cccc(NC(=O)Nc2ccccc2)c1 +O=C(Cc1ccsc1)NCCCNc1ncccn1 +CC(c1ccccc1F)N(C)C(=O)C1Cc2ccccc2C(=O)O1 +COc1ccc(C(=O)NCCc2ccccn2)c(OC)c1OC +O=S(=O)(NC1CC1)c1ccc(-n2cc(Br)cn2)cc1 +CCOCCc1nc(-c2ccc(Cn3nc(C)cc3C)cc2)n(C)n1 +C=CCNC(=O)NCc1ccc(OCC(F)(F)F)cc1 +O=C(Cn1cnc2c(oc3ccccc32)c1=O)Nc1ccccn1 +COc1ccc(CN(C)C(=O)COc2cccc3cccnc23)cc1 +CC(=O)Oc1ccc(C2NCCc3c(C)cccc32)cc1 +CN(C(=O)Cc1ccccc1)C(C#N)c1ccc2c(c1)OCO2 +Cc1ccccc1NC(=O)CSc1nnc2[nH]c(=O)cc(C)n12 +CN(C)C(=O)CCNC(=O)Nc1ccc2c(c1)COC2 +CC(=O)Nc1cccc(NCC(O)c2ccc(C)cc2)c1 +Cc1nc2ccc(NC(=O)CCc3nc(-c4ccco4)no3)cc2o1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccc(F)c(C#N)c1 +Cc1cc(-c2nc3c([nH]2)CC(C)(C)CNC3=O)n[nH]1 +Cc1ccn2c(=O)c(C(=O)N(Cc3cnn(C)c3)C(C)C)cnc2c1 +CC(C)(C)OC(=O)N1CCC2(CC(O)c3ccc(O)cc3O2)C1 +COCCCNC(=O)CCn1ncc2cc(C)ccc21 +COc1ccc(-c2c(O)c(=O)c3ccccc3n2C)cc1 +COc1cccc(OC)c1OCCN1CC(CO)CC1=O +CC(C)Cc1ncc(C(=O)NC(C)(C)CC(C)(C)C)c(N)n1 +Cc1ccc(C(=O)Nc2ccc(C(=O)N3CCCC3)cc2)cn1 +CC(O)(CNS(=O)(=O)c1ccc(F)c(Cl)c1)c1cccs1 +Cc1noc(C2CCCN(Cc3cncs3)C2)n1 +COc1cccc(-c2nc(-c3ccc(S(C)(=O)=O)cc3)no2)c1 +O=C(NCc1ccccc1-n1ccnc1)c1cc(F)c(F)cc1Cl +O=C(Cn1nc2n(c1=O)CCCCC2)N(Cc1ccccc1)C1CC1 +CCn1nccc1C(=O)Nc1nc2c(Cl)cccc2s1 +CC(C)Cc1ccc(C(C)NC(=O)NCc2cnn(C)c2)cc1 +CC1CC(C)CN(C(=O)NC(C)C(=O)N2CCCCC2C)C1 +N#CC(NC(=O)c1ccc2c(c1)OCO2)c1ccccn1 +O=C(NCc1ccsc1)c1cccc2ccccc12 +C=C1C2(C(=O)Nc3ccncc3)CCC(C2)C1(C)C +CC(=O)c1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1 +O=C(Nc1ccc(-n2ccnc2)c(F)c1)C1CC2C=CC1C2 +CCn1nc(C)c(CNC(=O)c2cc3c(Cl)cccc3n2C)c1C +Cc1cc(C(=O)OCC2CCC(=O)N2)c(C)cc1Br +NC(=O)Nc1ccc(C(=O)Nc2ccc(Cl)cc2F)cc1 +CCOc1ccc(-c2ccc3c(c2)CC(=O)N3)cc1 +CCCNC(=O)CNC(=O)C1CCCN(C(=O)Nc2ccccc2)C1 +Cc1noc(C(C)OC(=O)c2ccc(N3CCNC3=O)cc2)n1 +Cc1noc(C)c1C1CCCN1C(=O)Cc1ccsc1 +COCc1ccccc1C(=O)Nc1cccc(OCC(=O)N(C)C)c1 +C=CCOc1ccc(CN2CCOC3(CCCC3)C2)cc1OC +O=C(CCn1nnc2ccccc2c1=O)N=c1[nH]c2ccccc2[nH]1 +COC(=O)CN1C(=O)C2(OCCO2)c2cc(Br)ccc21 +OCC1CN(Cc2nc(C(F)(F)F)cs2)c2ccccc2O1 +c1ccc2sc(C3CCCN3CCn3cccn3)nc2c1 +CC(c1ccccn1)N(C)C(=O)Nc1ccccc1SCC(N)=O +COc1ccc(NC(=O)c2cc3occ(-c4cccnc4)c3[nH]2)cn1 +Cc1c(C(=O)NCCc2ccncc2)nc2ccc(Cl)cn12 +N#Cc1cc(NC(=O)CC(F)(F)F)ccc1OCC(F)(F)F +CCC1CN(C(=O)c2cc[nH]n2)CCC(=O)N1Cc1ccccc1 +CCSc1n[nH]c(N)c1S(=O)(=O)c1ccc(OC)cc1 +NC(=O)Cc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1 +CC(=O)c1ccc2c(c1)N(Cc1ccc(C)cc1)C(=O)CS2 +CC1CCCN(C(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)CC1 +Cc1ccc(CNc2c(-c3cn(C)nc3C)nc3cnccn23)cc1 +O=C(CN1CCN(c2ccccc2O)CC1)N1CCOCC1 +CN(C)C(=O)Cn1c(=O)n(Cc2cccs2)c2ncccc21 +OCCCn1c(Cc2cccs2)nc2cc(F)c(F)cc21 +CCCn1nccc1NC(=O)CCc1cccc(OC)c1 +Nc1ccc(C(=O)Nc2ccc(Cl)cc2)cc1F +Cc1nn(C(C)C)c(C)c1S(=O)(=O)N1CCCC2(C1)OCCO2 +CN1CCc2c(c(-c3ccccc3F)nn2CC#N)C1 +CC(CC(=O)c1cccs1)NC(=O)C1(O)CCCC1 +C=CCN(Cc1ccccc1Cl)C(=O)c1cc(C2CC2)n[nH]1 +CC1CN(C(=O)c2ccccn2)c2cc(Cl)ccc2O1 +NC(=O)c1n[nH]c2ccc(NCc3c[nH]nc3-c3cccnc3)cc12 +CN(C)c1ccc(C(=O)NC2CCCN(c3ccccc3)C2=O)cc1 +O=C(NCc1noc(CCc2ccccc2)n1)c1ccccc1F +O=S(=O)(NCCC(O)c1ccccc1)c1ccc(F)cc1 +O=C(CC(F)(F)F)N1CCN(C2CCCc3ccccc32)CC1 +Cc1cc(Cl)ccc1OC(C)C(=O)NCCCn1cncn1 +CCN(Cc1ccccc1C)C(=O)NCCN1CCOCC1 +NC(c1ccncc1)c1nccn1-c1ccccn1 +Cc1ccc(-c2nnn(CC(=O)NC3CCC(C)CC3)n2)cc1 +Cc1ccc(C(=O)NC2(C#N)CCC3(CC2)OCCO3)cc1Cl +Cc1ccc(S(=O)(=O)N2CCOc3ccc(F)cc32)c(F)c1 +N#Cc1ccc(NCc2cccc(C(=O)N3CCCCC3)c2)cc1 +CCOc1ccc(CNC(=O)C2CC=CC2)cc1C +CC(C)CCc1noc(CN2CCc3ccccc32)n1 +CC1(O)CCN(C(=O)CCS(=O)(=O)c2ccccc2)CC1O +CC(NC(=O)c1onc(-c2ccncc2)c1N)c1ccccc1 +Cc1cccn2cc(COC(=O)c3ccc(NC(=O)CC#N)cc3)nc12 +Cc1nc(NCC(C)C)c(N)c(OCC(C)C)n1 +CCc1nc(COc2cccc(C)c2C)sc1CO +COC(=O)C1CCN(C(=O)CCc2ccccc2)c2ccccc21 +O=C(CC(c1ccccc1)c1ccco1)NCc1cc(=O)[nH]cn1 +COCCNC(=O)N1CCC(c2nn(C)c(=O)n2C2CC2)CC1 +Cc1cc(C)n(CCCNC(=O)c2ccc(C(F)(F)F)nc2)n1 +Cc1nc(C(C)(C)NC(=O)Nc2c(F)cccc2F)sc1C +O=C(NCC1CCCCO1)c1cccc2cn[nH]c12 +Cc1cc(C)c(C#N)c(SC(C(N)=O)c2ccc(F)cc2)n1 +CCOC(=O)c1oc2c(c1C)C(=O)CC(C)(C)C2 +O=C(Cc1ccccc1)NCCc1ncc2ccccn12 +Cc1ccccc1C(=O)Nc1ccnc(-c2ccncc2)n1 +CC(C)(C)CC1CCCN1C(=O)Nc1ccc(C(N)=O)cc1 +O=C(Nc1ccc(N2CCCCC2)cn1)C1CCCN1C(=O)C1CC1 +CC(C)CCN(C(=O)NCc1cc(=O)[nH]c2ccccc12)C1CC1 +Cc1cc(NC(=O)c2ccccc2S(=O)(=O)C(C)C)ccn1 +C=CC1CCN(C(=O)NCc2ccnc(OC3CCC3)c2)CC1 +N#CCOc1cccc(CC(=O)Nc2ccc(F)c(C(N)=O)c2)c1 +CCN(CC)S(=O)(=O)c1cc(NC(=O)C(C)(C)C)ccc1C +Cc1nc(COc2cccc(C(=O)Nc3cnn(C)c3)c2)cs1 +Cn1cc(-c2cccs2)nc1CCNC(=O)c1ccccc1Cl +COc1cccc(-c2ccc(C(C)(C)O)c(=O)n2C2CC2)c1 +COc1ccc(C(NC(=O)N2CCC(CO)C2)C2CCOCC2)cc1 +CC(C)C(=O)N1CCN(CCC(=O)Nc2ccc(C(N)=O)cc2)CC1 +CN(Cc1ccccc1N1CCOCC1)C(=O)C1CCOCC1 +CC(Sc1ncnc2nc[nH]c12)c1nc(-c2cccs2)no1 +COC(=O)c1sc2cccc(F)c2c1CNC(C)=O +Cc1cc(C)c(S(=O)(=O)N(C)C(=O)c2cn(C)nc2C)c(C)c1 +Cn1nccc1CSc1nnc(SCc2ccnn2C)s1 +COc1ccc(C)cc1C(O)CCC(=O)NC(C)C +O=C(Cc1cc(-c2ccc(Cl)cc2)on1)NCc1ccncc1 +CCc1ccc(C2CCCCCN2C(=O)c2ccc(C)nc2)o1 +Cc1cnc2c(c1)nc(-c1ccc(F)cc1)n2CC#N +COC(=O)CCC(=O)Oc1cccc(C(C)(C)C)c1 +CC(=O)Nc1cccc(NS(=O)(=O)c2cc(C)on2)c1 +CCCn1cc(C(=O)Nc2ccc(C)c(C)c2)c(=O)c2ccc(C)nc21 +Cc1cc(C)cc(C(=O)Nc2ccc(N)cc2C)c1 +Cc1cccc(N)c1NCc1c[nH]c2ccccc12 +Cc1noc(CCCC(=O)Nc2ccccc2F)n1 +O=C1NCCCc2[nH]c(Cc3cccc(F)c3)nc21 +CCC1c2ccsc2CCN1C(=O)CCn1c(C)csc1=O +COc1cccc(F)c1C1NCCc2c(F)cc(O)cc21 +O=C1CC(c2ccccc2)S(=O)(=O)c2ccccc2N1 +Cc1sc2ncn(CC(=O)c3ccc4c(c3)CCC4)c(=O)c2c1C +O=C(NCC1CCCO1)c1ccn2c(-c3ccccc3)nnc2c1 +O=C(NCCN1CCOCC1)c1ccc(-c2nc[nH]n2)cc1 +O=C(Cn1c(=O)oc2ccccc21)Nc1cc(Cl)ccc1Cl +Cc1cccc(-c2nnc(-c3cccc(S(=O)(=O)N(C)C)c3)o2)c1 +c1ccc(OCc2nc(-c3ccc(-n4ccnc4)nc3)no2)cc1 +Cc1c(C(=O)CN2CCN(c3ncccn3)CC2)c2ccccc2n1C +CSc1ccc(NC(=O)c2cc(F)c(F)c(F)c2)cn1 +Cc1cc(Cl)ccc1NC(=O)N1CCN(C(=O)N(C)C)CC1 +CN(C)c1oc(COc2cccc(Cl)c2)nc1C#N +COc1ccc(NC(C)=O)cc1NC(=O)N1CCCC1CC(C)(C)C +Cc1nc(C(=O)N2CCCC2c2ccc3c(c2)OCCO3)cs1 +CC(C)(C)CNC(=O)c1[nH]cnc1C(=O)NCc1ccco1 +CC(C)Oc1ccc(CNC(=O)CCn2cncn2)cn1 +O=C(CCc1c[nH]c2ccccc12)N1CCC(O)C1 +CCOC(=O)Cn1cnc(-c2cccs2)cc1=O +CCn1cc(C(=O)NCC(C)N2CCN(c3ccccc3)CC2)cn1 +Cc1cnn(CCC(=O)NCc2ccc(-n3cccn3)cc2)c1 +CCn1cnnc1CNC(=O)C(OC)c1ccccc1 +COCCNc1nc(Nc2ccccc2)nc2nccnc12 +CS(=O)(=O)N1CC2OCC(CC(=O)NCc3ccccn3)C2C1 +COCCNC(=O)CSc1nnc(C2CCCCC2)n1N +CC(C)Oc1cccc(-c2ccc(N)c(=O)n2C(C)C)c1 +COCCCC(=O)Nc1nc2cc(Cl)ccc2n1C +Cc1occc1C(=O)OCc1cc(Cl)c2c(c1)OCCCO2 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)NC(C)CCCC(C)C)ccc21 +Cc1ncc(N)cc1C(=O)Nc1nc(C)c(C)s1 +Cc1ccccc1-n1c(C)nnc1SCc1cccnc1 +CN(CC12CC3CC(CC(C3)C1)C2)C(=O)c1cn(CC(N)=O)nn1 +Cc1n[nH]c(SCC(=O)NCc2ccc(C(C)(C)C)cc2)n1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccc2c(c1)CCO2 +COC(=O)Cc1cccc(NCc2ccc(C)cn2)c1 +Cc1ccc(S(=O)(=O)N(C)C(C)C(O)c2ccccc2)cc1 +CC(NC(N)=O)C(=O)NC1CCC2(CC1)OCCO2 +O=C(Nc1cc[nH]n1)c1ccn(-c2cccc(C(F)(F)F)c2)n1 +COc1ccc(OC)c(C2CCCN2C(=O)Cc2ccc(C)nc2)c1 +Cc1ccc(CNS(=O)(=O)c2cccc(-n3cnnn3)c2)s1 +CCC(CC(=O)OC)c1ccc2c(c1)OCCCO2 +N#Cc1cnc(NC(=O)c2ccc(C(F)(F)F)cc2)s1 +Cc1cc2nc(N)nn2cc1-c1ccc2ncccc2c1 +O=C(Cn1c(SC(F)F)nc2ccccc21)NCc1ccncc1 +CC(NC(=O)c1cccc(-c2ccoc2)c1)C(=O)NCc1ccccc1 +Cc1cc(C)cc(C(=O)N2CCC(NC(=O)c3cnn(C)c3)CC2)c1 +C=C(C)COc1cccc(-c2cc(C(N)=O)nc(N)n2)c1 +Cc1cccc(N2CCN(c3ccc(SCC(N)=O)nn3)CC2)c1 +COC(=O)N(C)c1ccccc1C(=O)N1CCOCC1 +CN(C(=O)c1ccc2c(c1)NC(=O)CS2)c1cccc(C#N)c1 +CN(CC(=O)NC1CC1)C(=O)CCCn1ccc2cc(Cl)ccc21 +N#Cc1cccc(NC(=O)CCC(=O)c2ccc(Cl)cc2)c1 +COC(=O)C(C)(NCC(F)(F)F)c1ccccc1C +COc1cccc(CCNC(=O)NCc2cscn2)c1 +NC(=O)c1ccsc1NC(=O)COC(=O)CC1CCCC1 +CCCCN(C)C(=O)NCc1cccc(COC)c1 +CCC(C)n1ncc(C(=O)NCc2cnn(C)c2C)c1C1CC1 +C=CCOc1cccc(NC(=O)NCCc2cnn(C)c2)c1 +CCn1c(SCC2CCCO2)nnc1-c1ccoc1C +Cc1cc(Cl)ccc1NC(=O)Cn1ncc(Cl)c(Cl)c1=O +COc1ccc(N(CC(=O)N(C)C)S(=O)(=O)c2ccccc2)cc1 +Cc1nccc(CNC(=O)CCc2cccc(Cl)c2)n1 +CN(C(=O)c1ccc(F)c(F)c1F)C(C#N)c1cccs1 +COC(=O)CSc1nc(N)c2c3c(sc2n1)CCC3 +CC(=O)Nc1ccccc1NC(=O)c1ccccc1 +Cc1nnc(SCC(=O)c2ccccc2)n1Cc1ccccc1 +CCCS(=O)(=O)N1CCC2CC(c3ccncn3)OC2C1 +COC(=O)c1c(NC(=O)COc2ccc(C)cc2)sc2c1CCC2 +COc1ccc(-c2cnn(C)c(=O)c2CC#N)cc1F +CC(=O)N1CCN(C(=O)NCc2nc(C)cs2)CC1 +COC(C)C(=O)Nc1nc2c(ccc3ccccc32)s1 +N#Cc1ncn(Cc2noc(-c3ccc(Cl)cc3)n2)n1 +COCC(=O)NC(C(=O)NCc1ccc(F)c(Cl)c1)C(C)C +Cc1ncc(CNC(=O)Nc2cc(C#N)ccc2OC(F)F)s1 +CC1CCN(C(=O)c2ccncc2)C1c1cccc(F)c1 +Cc1ccc(NC(=O)CN(CCC(N)=O)c2ccc(F)cc2)cc1C +O=C(NCC1CCCO1)Nc1ccc2c(c1)oc1ccccc12 +CC(Oc1ccccc1C#N)C(=O)N1CCN(CCO)CC1 +COc1cc(-c2noc(C3Cc4ccccc4N3C(C)=O)n2)ccn1 +Cc1ccc(OCC(=O)NC2CCN(c3ccccc3C#N)CC2)cc1 +CCc1cc2c(Nc3cnn(CCOC)c3)ncnc2s1 +CC(CCCO)NC(=O)N1CCCC1COc1ccccc1 +O=C(CS(=O)(=O)c1ccc2ccccc2n1)N1CCCC1 +CCOC(=O)c1cnn2ccc(NC(=O)c3cccc(C#N)c3)cc12 +N#CCSc1nnc(Nc2ccc3c(c2)OCO3)s1 +CC(C)C(=O)NC1CCN(c2cncc(-n3cccn3)n2)CC1 +CN(Cc1cscn1)C(=O)c1ccc(-c2ccco2)[nH]c1=O +Cn1nncc1CN1CC=C(c2cccs2)CC1 +O=C(NCCCCOC1CCCCCC1)c1n[nH]c(=O)[nH]1 +CCC(C)C(=O)Nc1cc(C(=O)NC)ccc1Cl +CN(C1CCC(C)(C)CC1)S(=O)(=O)c1cccc(C#N)c1 +CC(C)(C)CCCC(=O)NC1CCN(C(=O)c2cnccn2)CC1 +CC(C)(C)OC(=O)N1CCCC(CCCOc2ncccn2)C1 +Clc1ccc2c(c1Cl)C(c1nc[nH]n1)NCC2 +Cc1cc(C)n(-c2cc(SCc3ccccc3)ncn2)n1 +CC(C)S(=O)(=O)c1ccccc1C(=O)Nc1cnn(C(C)(C)C)c1 +CNC(=O)c1nccc(C(F)(F)F)c1OC1CC1 +O=C(CN1CCN(c2cccc(Cl)c2)C1=O)NCc1ccncc1 +Cc1cc(C(=O)N2CCC3(CCC(C(=O)N(C)C)O3)CC2)c(C)o1 +COCC(O)CN(C)c1ccc(C#N)cc1C(F)(F)F +COc1c(F)cc(NC(=O)Cn2nc3ccccn3c2=O)cc1F +NC(=O)C1CCN(C(=O)C2CCCN(C(N)=O)C2)CC1 +CCN(CC1CC1)C(=O)CCC(=O)Nc1nccs1 +Cn1c(SCC(=O)c2cccc(C(F)(F)F)c2)nnc1C1CC1 +CN(C)C(=O)CCCn1ccc(Nc2ncnc3ccsc23)n1 +CCOc1ncnc(N(CC)c2cccc(C)c2)c1N +N#Cc1ccc(OCC(=O)Nc2ccc3c(c2)OCO3)c(Cl)c1 +COC(=O)CNc1ccc(C(=O)NC2CCOCC2)cc1 +Cn1nc(C(=O)NCc2cccc(F)c2)cc1-c1ccco1 +CC(=O)C(C)Oc1cc(C)cc2oc(=O)c3c(c12)CCCC3 +NC(=O)CSc1nnc(Cc2cccc3ccccc23)n1N +CCOCC(=O)N1CCC(C(=O)OC)c2ccccc21 +COc1cc(-c2nc3c([nH]2)c(-c2ccccc2)nn3C)cc2c1OCO2 +O=S(=O)(N1CCOCC1)N1CC(c2ccccn2)C1 +Cc1cc(NC(=O)c2cc(-c3cccnc3)nc3ccccc23)ccn1 +Cc1cc(C(C)NC(=O)NC(C)C(=O)N2CCCCC2)c(C)s1 +CC(=O)c1sc(C(N)c2cc(C)cc(C)c2)nc1C +CNC(=O)C(C)CN(C)C(=O)c1c[nH]nc1-c1cccc(Cl)c1 +CC(C)Cc1c(CO)nnn1-c1cccc(C(=O)OC(C)C)c1 +COc1ccc(-c2cc(=O)c3ccc(O)cc3o2)cc1O +COc1cccc(C(=O)CCCC(=O)N2CCN(C)CC2)c1 +O=C(CCn1cncn1)NCC12CC3CC(CC(C3)C1)C2 +COc1ccc(C(=O)OC2CCOC2=O)c(OC)c1 +O=C(NCCCc1ccccn1)C(c1cccnc1)N1CCCC1 +CC(O)(CNC(=O)c1ccc(CNC(N)=O)cc1)c1ccc(F)cc1 +C#Cc1cccc(NC(=O)NC2CCN(c3ccccc3)C2=O)c1 +Cc1cc(C)cc(C(=O)N2CC(=O)Nc3ccccc32)c1 +Cc1ncsc1COC(=O)c1cn(C)nc1C(C)(C)C +CCCOc1cc(C)c(C(=O)CCN2CCOCC2)cc1C +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)Cc1ccc(F)cc1 +Cc1nc(C)n(C2CCCN(C(=O)CCCOc3ccccc3)C2)n1 +Cc1cnc(C2NCCc3c(OC(F)F)cccc32)cn1 +COc1cccc(C(=O)Nc2ccc(NC(=O)c3ccccc3)nc2)c1 +Cc1cc(C)c(SCC(=O)N(CCC#N)CCC#N)c(C)c1 +CC1CN(Cc2cccc(OC3CCCC3)c2)CC(C(N)=O)O1 +CC(C)CC(NC(=O)CNC(=O)NC1CC1)c1cccs1 +Cc1cccc(-c2cccc(NC(=O)NCC3(CO)CC3)c2)c1 +CCN(C)C(=O)c1csc(-c2ccc(OC)cc2Cl)n1 +CCc1cc(NC(=O)c2cccc(C(=O)OC)c2)[nH]n1 +COc1ccc(S(=O)(=O)NCc2ccccc2Cl)c(OC)c1 +CCOc1cc(NC(=O)c2cc(NC(C)=O)ccc2F)ccc1OC +Cc1cc(C)n(-c2ccc(C(=O)NCc3ccccc3F)cc2)n1 +Cc1ccccc1NC(=O)Cn1c(C)nc2cc3c(cc21)OCCO3 +CC(=O)c1ccc(OCC(=O)c2ccc3c(c2)NC(=O)CO3)cc1 +N#Cc1cccc(NC(=O)N2CCCC2CC(O)c2ccccc2)c1 +CC1CN(C(=O)c2ccc(NC(=O)C3CCC3)cc2)CC(C)O1 +CSc1cccc(-c2nnc(NC(=O)c3cc(C)n(C)n3)o2)c1 +COCCCNC(=O)c1cccc(NC(=O)C2CCC2)c1 +CC(NC(=O)c1ccccc1S(C)(=O)=O)c1ccc(F)c(F)c1 +O=c1c(NCCc2ccccc2)nccn1-c1ccc2c(c1)OCCO2 +COC(=O)CC(NC(=O)c1cnccn1)c1ccccc1Cl +COCc1nc(COc2ccccc2F)sc1C(C)=O +CCCn1nc(-c2ccc(Cl)cc2)cc(CC#N)c1=O +CCCC1CN(C(=O)Nc2cc(F)c(F)c(F)c2)CCO1 +Nc1cccc(S(=O)(=O)N2CCC(CO)CC2)c1 +NC(=O)C1Cc2ccccc2N1C(=O)C1CCCO1 +COc1cc(N)cnc1Nc1ccccc1Br +Cc1n[nH]c2ncc(NC(=O)c3c[nH]c4cccc(F)c34)cc12 +Cc1cc(C)nc(SCc2cc(F)ccc2N)n1 +CC(=O)Nc1c(C)ccc(NC(=O)C2(c3ccccc3)CCC2)c1C +O=c1cc(C2CCCN(Cc3ccccn3)C2)nc(-c2ccncc2)[nH]1 +CSc1ccccc1C(=O)N1CCC(Oc2ncccn2)CC1 +O=C(C1CCCC1)N1CCC(c2ccc(-c3cncnc3)cn2)CC1 +O=C(Nc1cccnc1-n1cccn1)c1ccc(Cn2ccnc2)cc1 +O=C(NCC(c1ccsc1)N1CCOCC1)c1cccs1 +COC(=O)c1ccc(C)c(NC(=O)C2(C)CC2(Cl)Cl)c1 +COCC(C)(C#N)NC(=O)c1ccc(C)cc1F +CCn1cc(Cl)cc1C(=O)N(CCO)C1CCCC1 +Cc1cc(OC(C)C(=O)N2CCOCC2)ccc1C(C)C +O=C(CCC(=O)Nc1nccs1)NCC1CCCc2ccccc21 +Clc1ccc(OCc2n[nH]c3ncccc23)cc1 +Cc1cc(CNc2ccc(-c3cnco3)cc2)ccc1-n1cncn1 +Cc1ccc(OC(=O)CCn2cnc3ccccc3c2=O)cc1C +CSc1nc(-c2ccco2)nc(C)c1C(=O)NCC1CCCO1 +C=C(C)CN(CC)C(=O)CN1CCOCC1C1CC1 +Cc1cccnc1NC(=O)c1cccc(S(=O)(=O)NCCC#N)c1 +Cc1ccc(CC(=O)NCCc2ccccn2)cn1 +CC(=O)N1CCCC(C(=O)Nc2cc(-c3ccncc3)n[nH]2)C1 +COc1ccnc(N2CCCN(C(=O)C(C)OCC3CC3)CC2)n1 +Cc1nc2c(Cl)cc(C(F)(F)F)cn2c1C(N)c1cccnc1 +CC1CCCCN1C(=O)c1ccc(-c2ccncc2)nc1N +O=C1CN(C(=O)c2ccc(CNC(=O)NC3CC3)cc2)CCN1 +O=C(c1ccoc1)N1CCC(Nc2cnn(CC(F)(F)F)c2)CC1 +CC(C)CCN(C)C(=O)c1csc(S(N)(=O)=O)c1 +CC(c1nccn1C1CC1)S(=O)(=O)N1CCCC1 +Cc1ccnc(SCC(=O)Nc2cccc3nonc23)n1 +CCOC(=O)N1CCN(C(=O)C(c2cccnc2)N2CCCC2)CC1 +Oc1c(F)ccc2c1CCNC2CC1CCOCC1 +CC(C)CN1CC23C=CC(O2)C(C(=O)OCc2ccccc2)C3C1=O +O=C(NCCO)Nc1ccc(N2CCOC2=O)cc1 +COc1ccc(-c2cnc(C)o2)cc1S(=O)(=O)N1CCOCC1 +CCN(CC)c1ncc(CN2CCN(C(C)C(N)=O)CC2)s1 +Cc1cc(C)n(CC(=O)N2CCOC(C(=O)N3CCCCCC3)C2)n1 +CCCc1nc(CSc2nnc(C3CC3)n2CC)cs1 +Cc1ccc(CNC(=O)NC(C)CCc2cccn2C)c(N(C)C)c1 +COc1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +CC(C)(C)OC(=O)NCC(=O)N1CCCC1(C)C +CC(C)COC1CCN(C(=O)NC(C)c2ccc3c(c2)OCO3)CC1 +O=C(CCn1ccccc1=O)Oc1ccc2c(c1)OCO2 +CCOC(=O)C(C)(C)N(C)Cc1cn(-c2ccccc2)nc1C +CC1CCCC(NC(=O)NCc2ccncc2)C1C +Cc1cccc(NC(=O)Cn2nc3c(cc2=O)CCCCC3)c1C +COc1ccnc(NC(=O)C2CC(=O)N(C3CCCCCC3)C2)c1 +Cc1ccc(C(O)(CCNC(=O)Nc2cccnc2)C(F)(F)F)o1 +Cc1ccc(C(=O)N2CCc3ccccc3C2C)cc1F +Fc1ccc(NCc2cncs2)c(OCC(F)(F)F)c1 +COc1ccccc1CCCN1CCN(C(=O)c2ccoc2)CC1 +Cc1ccc2c(C(=O)NCC(C)O)nccc2c1N +O=C(Nn1cnc2c(cnn2-c2ccccc2)c1=O)c1cccs1 +Cc1cccc(OCCNC(=O)C2CCCN(S(C)(=O)=O)C2)c1 +CCn1cc(C(=O)NCc2csc(C(C)C)n2)c(C(C)C)n1 +Cc1noc(C)c1COc1ccc(C2NC(=O)c3ccccc3N2)cc1 +COc1ncccc1C(=O)NCCn1cnc(C)cc1=O +Cc1csc(C2CCCN(C(=O)c3ccoc3)C2)n1 +O=C(NCCc1ccccc1)c1ccc(CN2CCCC2=O)cc1 +Cc1noc(C)c1CC(C)NC(=O)c1ccc(OCC(F)F)nc1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCC(=O)C1CC1 +CN(CC1CCCOC1)c1cc(N(C)CC2CCCOC2)ncn1 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+Clc1ccc(-c2ccnc3ncnn23)cc1Cl +COCCN(Cc1ccco1)S(=O)(=O)N1CC(C)OC(C)C1 +N#CC(C(=O)c1ccccc1Cl)c1nc2ccccc2[nH]1 +CC(C)(C)OC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +O=C(CNC(=O)c1ccc(F)c(F)c1F)c1ccc(F)cc1 +CCCN1C(=O)C(Cc2ccccc2)Oc2cc(O)ccc21 +O=C(NCc1ccnc(-n2cccn2)c1)NCC1CCOC1 +CC(C)OC(=O)CCCNC(=O)c1cccs1 +O=C(Nc1cc(-c2ccncc2)n[nH]1)c1ccc(F)cc1F +N#Cc1ccccc1COc1ccc2ccc(=O)oc2c1 +COc1ccc(F)cc1NC(=O)CC(F)(F)F +CN(C)C(=O)c1ccc(C(=O)OCc2ccccc2Cl)cc1 +Cc1cc(=O)[nH]c2c1c(=O)[nH]n2C1CCCCCC1 +CC(=O)c1ccc(S(=O)(=O)Oc2ccccc2)cc1 +COc1ccc(F)c(NC(=O)CCc2ccccn2)c1 +Cc1cc(C)cc(NCc2nc3n(n2)CCCCC3)c1 +NC(=O)CCc1nnc(SCC2CCCO2)n1C1CC1 +O=S(CC=CCS(=O)c1ccccc1)c1ccccc1 +O=C(NCC(O)c1ccccc1Cl)NC1CCCc2ccccc21 +Cc1cccc(Cn2cc(NS(=O)(=O)c3cnn(C)c3)cn2)c1 +CC(=O)N1CCC(C(=O)N(CCC#N)CCC(F)(F)F)C1 +COc1ccc(C(=O)NCC(O)(c2ccccc2)C2CC2)cc1OC +CN(Cc1ccco1)C(=O)CSc1nnnn1-c1ccc(O)cc1 +CCC(CCO)NC(=O)Nc1cc(Cl)c(OC)cc1OC +CC#CC1NCCc2cc(OC)c(OCCC)cc21 +Fc1ccccc1-c1noc2c1CN(C1CCOCC1)CC2 +Cc1ocnc1C(=O)N1CCCCC1CCc1ccccc1 +COc1ccc(Cl)cc1C(O)Cc1ccsc1 +CC1CN(C(C)(C)CNC(=O)c2ccc[nH]c2=O)CC(C)O1 +O=C(NCCc1c[nH]c2ccccc12)c1ccccn1 +Cc1cccc(NC(=O)NCc2ncn(C)n2)c1C(=O)N1CCCC1 +Cc1cc(F)ccc1CCNC(=O)c1csc(-c2cnn(C)c2)n1 +CC(O)CN(C)C(=O)c1cccc(OC(F)F)c1 +CCC(=O)NCC(=O)Nc1cccc(C(=O)NC2CC2)c1 +O=C(Nc1cccnc1N1CCOCC1)c1cnns1 +CC1CCCN(C(=O)c2n[nH]c(=O)c3ccccc23)C1 +COc1ccc(OCc2nc3cc(OC)c(OC)cc3c(=O)o2)cc1 +Nc1ccc(S(=O)(=O)Nc2ccc(F)c(Cl)c2)c(Cl)c1 +CCC(O)c1cc(Cl)cc2c1NC(=O)C2(C)C +CC(Sc1ccccn1)C(=O)NCC(=O)N1CCCC1 +CNC(=O)c1ccc(S(=O)(=O)Nc2ccc3c(c2)CCC3)cc1 +CCOC(=O)c1ccc(NC(=O)Nc2cccnc2)cc1 +Cc1n[nH]c(C)c1C1COCCN1C(=O)c1cc2ccccc2[nH]1 +Cc1cnc(CCN(C)Cc2sc(N(C)C)nc2C)s1 +Brc1ccsc1COCC1CCCCO1 +COc1cc2nc(C(C)O)n(-c3ccncc3)c2cc1OC +CCC(=O)Nc1cccc(C(=O)Nc2ccc3c(c2)OCO3)c1 +CC(Cc1ccco1)NCc1ccc(Cl)c(N)c1 +O=C1COc2cc(C(=O)Nc3cc(F)cc(F)c3)ccc2N1 +Cc1cc2c(=O)n(CC(=O)Nc3cc(C(C)(C)C)no3)cnc2s1 +Cc1nc(-c2ccccc2)sc1C(=O)NCCNc1ncccn1 +CC(C)(CO)NC(=O)CCOc1ccc2c(c1)CCCC2 +COc1ccc2c(=O)cc(C(=O)NCC(=O)N3CCCCC3)oc2c1 +COc1ccc(-c2cnc3ncnn3c2N)cc1OC +Cc1cc(C)c(-n2nc(CO)c(=O)cc2C)c(C)c1 +CN(C(=O)C(OC1CCCC1)c1ccccc1)c1nccs1 +CC(=O)N1CCN(C(=O)Cn2cnc3ccc(F)cc3c2=O)CC1 +Cc1cc(C(=O)NCCNc2cccnc2)nc(C)n1 +CCc1ccccc1OCC(CC#N)N1CCOCC1 +COc1ccc(NC(=O)N(C)CCCC2CCCO2)cc1OC +CC(Nc1nc2ccccc2s1)C(=O)NC1CCCC1 +COc1ccc2c(C(=O)NCCn3cc(Cl)cn3)cc(=O)oc2c1 +Cc1cc(CC(=O)NC2COc3ccccc3C2=O)n[nH]1 +COCCNC(=O)CSc1ncnc2c1cnn2-c1ccccc1 +CC(=O)c1cccc(NC(=O)c2ccc3c(c2)nnn3C2CCCC2)c1 +O=C(c1cccc(-c2ccoc2)c1)N1CCOC2(CCCC2)C1 +CC(NCC(F)(F)F)c1cn(-c2ccccc2)nn1 +CCOC(=O)N1CCN(C(=O)c2ccc(OC)cc2O)CC1 +NC(=O)c1cccc(Oc2ccc(NC(=O)C3CC=CCC3)cc2)c1 +O=C(COC1CCCCC1)NCc1ccc(-n2cncn2)cc1 +O=C(C1CC1)N1CCC2(CCN(c3ncccc3F)CC2)C(CO)C1 +C=CCN(CC1CCCCC1)S(=O)(=O)C1CCCN(C(C)=O)C1 +NC(=O)c1ccccc1NC(=O)C1Cc2ccccc2CN1 +C=CCN(CC(F)(F)F)C(=O)Cc1csc(-c2cccnc2)n1 +CCCC(=O)NCc1nnc2c(C(F)(F)F)cc(Cl)cn12 +Cc1ccc(C(=O)NCC(=O)NC(C)c2ccc3c(c2)OCO3)s1 +O=C(NCc1ccccc1)NCC(O)(c1ccccc1)C1CC1 +Cc1cc(Cl)cc(C)c1NCc1ccc(O)cc1 +Cn1nnnc1-c1cccc(NCC(=O)Nc2ccccc2)c1 +CC(C)(C)C(NC(=O)NCCC(=O)N1CCCC1)c1ccc(F)cc1 +CCCCS(=O)(=O)N1CCC(c2nnc(-c3ccco3)o2)CC1 +CCOC(=O)N1CCN(C(=O)Nc2ccc(OC)c(OC)c2)CC1 +NC(=O)C1Cc2ccccc2CN1CC1CCCO1 +CCCC(NC(N)=O)C(=O)NCC1CCC(CC)CC1 +CCOCCC(=O)Nc1nc(-c2cccs2)ns1 +Clc1cccc(CN2CCc3nc(N4CCOCC4)ncc3C2)c1 +O=C(Nc1cncnc1N1CCCC1)c1cc(F)cc2[nH]cnc12 +O=C(NC1CC1)C1CCCN(C(=O)C2CCCCC2C(F)(F)F)C1 +CC1Cc2ccccc2N1S(=O)(=O)c1ccc2c(c1)CCN2 +CC(NC(=O)C1CC1c1cnn(C)c1)c1cccc(Cl)c1Cl +CN1CCN(C(=O)C2CN(C(=O)c3ccc(F)c(F)c3)C2)CC1 +Cn1cc(-c2ccc(C(=O)N3CCOCC3)cn2)cn1 +CCCCN(C)S(=O)(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +Cc1cc(C)c2c3c(cn2n1)c(=O)n(C)c(=O)n3C +COc1ccc(NC(=O)C2(c3ccccc3)CCOCC2)cc1 +COc1ccc2c(C)c(CCC(=O)Nc3cccnc3)c(=O)oc2c1 +COCc1ccccc1CNC(=O)c1ccc(C)s1 +CN1CC(NC(=O)NCCc2nc3ccccc3s2)CCC1=O +OCCc1cn(CC2CCN(C3N=CN=C4N=CN=C43)CC2)nn1 +Cc1cc(NC(=O)c2c[nH]c3ccccc3c2=O)c2cc(F)ccc2n1 +COCc1ccc(C(=O)NCCSc2ccccn2)o1 +C=CCNC(=O)C(CC)(C(F)(F)F)C(F)(F)F +O=C(CCCNC(=O)c1cc2sccn2c1)Nc1ccccc1 +O=C1CC(Nc2ccc3cccc(Br)c3n2)CN1C1CC1 +Cc1ccc(C(=O)NCC(C)N2CC(C)OC(C)C2)cn1 +Cc1nc(CN2CCN(C(=O)c3ccccn3)CC2)cs1 +c1ccc(-c2noc(-c3cc(-c4cccs4)n[nH]3)n2)nc1 +Cc1csc(C(NC2CCN(CC(F)(F)F)C2)C2CC2)n1 +Cn1cc(C(=O)NCCc2ccc(C(F)(F)F)cc2)ccc1=O +CCOC(=O)c1csc(CNC(=O)c2cc(C)c(CC)s2)n1 +O=C(c1ccccc1F)N1CCCCC1CCO +CCC(CC)NC(=O)COc1ccc(N)cc1Cl +CC1(C)OCC2(CO1)CN(S(=O)(=O)c1cccc(Cl)c1)C2 +O=C(NC1CCCCC1)c1ccc(-n2ccnc2)nc1 +CC(C)OC(=O)C(C)N1CCNc2cc(Cl)ccc21 +CC(=O)Nc1ccc(OC(=O)Cc2c(F)cccc2Cl)cc1 +Cc1cc(C)c(-c2csc(NC(=O)c3ccnn3C)n2)c(C)c1 +Cc1n[nH]cc1NC(=O)c1cnn(C(C)(C)C)c1C +Fc1ccc(-c2cn(CCCN3CCOCC3)nn2)cc1 +CCOc1ccc(NC(=O)c2cc(C)nc3onc(C)c23)c(C)c1 +CC(C)Nc1nnc(-c2ccc(=O)n(C)n2)s1 +CC1CC(C)CN(C(=O)C(C)Sc2nnc(-c3ccco3)n2C)C1 +CCOc1ccc(CNc2cc(F)ccc2OC)cc1OC +Cn1cc(C(=O)NCC2(NC(=O)OC(C)(C)C)CCCCC2)cn1 +CCOc1ccccc1NC(=O)Cc1nn(C)c(=O)c2ccccc12 +COc1nccnc1N1CCC(NC(=O)CC2CCCC2)C1 +Cc1ccc(CN(C)C(=O)c2cnc(C)cn2)cc1 +Cc1nc(C)c(CCNC(=O)NCC2COc3ccccc3O2)s1 +CC(O)CCC(=O)N1CCN(c2ccccc2)CC1 +O=C(Nc1ccncc1)c1cc(F)c(F)cc1F +CC(Nc1nc2ccccc2cc1CO)c1ccc(-n2cncn2)cc1 +O=C(NC1CCOc2ccccc21)c1nccc2ccccc12 +COC(=O)c1sc2snc(SC)c2c1N +CCCC(=O)Nc1cccc(NC(=O)c2cccnc2OCC)c1C +Nc1c(-c2ccccc2)nsc1C(=O)NC1CCCCC1 +COc1ncc(C2NCCc3c(O)cccc32)c(OC)n1 +COCc1nc(CNC(=O)CC23CC4CC(CC(C4)C2)C3)no1 +CC(=O)Nc1ccc(CC(=O)NCC2CCCO2)cc1 +CC1CN(C(=O)C2CC2c2cccnc2)CC1N1CCOCC1 +O=C(CC1CCCC1)N(Cc1cnc2ccccn12)C1CC1 +COc1ccc(-c2nc(CC(=O)NCCO)cs2)cc1OC +CN(Cc1cccnc1)S(=O)(=O)c1ccc(N)cc1 +Cc1ccc(C(=O)NCCc2nc(C(C)(C)C)cs2)cn1 +CCn1nnc2c(SCc3cc(OC)cc(OC)c3)ncnc21 +CCOc1ccc(Cl)cc1CCNC(=O)Cc1csc(C)n1 +COc1cccc(CSc2n[nH]c(=O)n2CC2CCCO2)c1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)N(C)c1ccc(F)cc1 +NC(=O)COc1ccc(C(=O)OCc2ccccc2)cc1N +COc1ccc(CNC(=O)c2cc3c(s2)CCCC3)cn1 +Cc1ccc(CNC(=O)CCc2ccccc2N)cc1 +O=C(NCCCn1ncccc1=O)Nc1ccc(F)cc1F +COC(CNS(=O)(=O)c1ccc(F)c(C)c1)c1cccc(F)c1 +CCC(C)C(=O)CSc1nc(-c2ccc(OC)cc2)n[nH]1 +Clc1ccccc1-n1nc(-c2ccncc2)c2c1CCNC2 +CCOc1ccccc1NC(=O)Nc1cc(C)ccn1 +O=C(CNC1=NS(=O)(=O)c2ccccc21)NCc1ccco1 +Cc1ccc(CSc2nc3ccncc3[nH]2)cc1 +COc1ncccc1CNC(=O)NCC1(c2ccc(F)cc2F)CC1 +CC(=O)Nc1cc(NCc2sccc2C)ccc1F +CC(=O)Nc1nc(CC(=O)Nc2ccccc2C(N)=O)cs1 +N#Cc1ccccc1OCC(=O)N1CCCC1c1noc(C2CC2)n1 +NC(=O)c1ccc(NC(=O)c2csc(-c3cccs3)n2)cc1 +CCOC(=O)c1cc(-c2cc(C)cc(N)c2OC)nn1C +Cc1nnc(C(C)N2CCN(C(C)C(=O)N3CCCC3)CC2)o1 +COc1cc(OC)cc(OCCc2nc3c(s2)CCN3)c1 +CCN(CC)S(=O)(=O)c1cc(C(=O)NC2CC2)ccc1Cl +CCCCNC(=O)Cc1noc(-c2n[nH]c(=O)c3ccccc23)n1 +CCC(C)C(=O)NCCC(=O)N1CCN(c2ncccn2)CC1 +COc1cccc2c1OCC(NC(=O)Cc1cccc(F)c1F)C2 +O=C(NC1CC1)c1cc2sccc2n1Cc1ccccc1F +COc1c(C)cnc(CNC(=O)C2Cc3ccccc3O2)c1C +Cn1cccc1C(=O)N1CCOC2(CCCN(c3cnccn3)C2)C1 +Cc1ccoc1C(=O)NCc1ccc(C(F)(F)F)cc1 +Cc1cc(C(C)(C)C)cc(C)c1CCNC(=O)CNC(N)=O +COc1ccccc1OC1CN(C(=O)Cc2cccc(SC)c2)C1 +O=C(OCCCn1c(=O)[nH]c2ccccc21)c1ccc2nccnc2c1 +CNC(=O)c1ccc(C)c(NC(=O)NCCN2CCNC2=O)c1 +O=C(CCc1nc2ncccc2[nH]1)N1CCOCC1C1CC1 +CCOc1ccccc1OCCCn1cnc2ccccc2c1=O +CN(CC1CCCN1C(=O)c1cncc(F)c1)c1ccccc1 +CCC(C(=O)N1CCC(O)(C(F)(F)F)C1)c1ccccc1 +COC(=O)c1ccc(S(=O)(=O)Nc2cnn(C)c2)c(C)c1 +COc1ccc(C(O)C(C)NC(=O)c2n[nH]c3ccc(C)cc23)cc1 +O=C(NCc1cccs1)Nc1cccc(C(=O)N2CCOCC2)c1 +O=C(Nc1ccc(Cl)c(Cl)c1)n1ccc(=O)[nH]c1=O +CCCC1CN(C(=O)c2ccc(OC)nn2)CCO1 +Cc1ccc(CNC(=O)C2CCN(c3ccc(N(C)C)nn3)CC2)o1 +COc1ccc2[nH]c(C(=O)N3CCCC(NC(=O)C(C)C)C3)cc2c1 +Cc1cc(C(=O)N2CCCN(Cc3nccn3C(C)C)CC2)no1 +O=C(c1ncoc1C1CC1)N1CCN(CCn2cncn2)CC1 +Cc1c(CNC(=O)c2ccc(OC(C)C)cc2)cnn1C +O=C(Nc1ccccc1C(=O)N1CCCCCC1)C1CCC1 +CCc1nc2cc(N)ccc2n1Cc1ccc(C)s1 +Cc1n[nH]c(=O)nc1N1CCC(Cc2ccccc2)CC1 +CN1CCN(C(=O)NCCc2nnc3n2CCC3)Cc2ccccc21 +Cc1ccc(-n2nc(-n3cnc4ccccc43)cc2N)cc1 +O=C(NC(c1ccccc1)c1ccncc1)c1cccnc1 +O=C(Oc1ccc(F)cc1)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +CSc1nc(C)cc(C(=O)N2CCN(c3ncccn3)CC2)n1 +COC(=O)c1ccc2c(c1)CCN2C(=O)C(C)Cc1c(C)noc1C +COc1ccccc1-c1c(C#N)nnn1-c1cccc(C)c1 +c1cnc(NCCCNc2ncnc3sccc23)nc1 +Cc1nc(-c2ccccc2)c(C(=O)N2CCC(CO)C(O)C2)s1 +C=CCOC(C)C(=O)Nc1cccc(Cl)c1N(C)C +COc1ccc(OCC(=O)N2CCC(Oc3cccnc3)CC2)cc1 +COC(=O)c1ccc(C(=O)N2CCN(Cc3cc(C)on3)CC2)s1 +CCCC1CN(C(=O)Nc2ccc3c(c2)C(=O)CCC3)CCO1 +CC(=O)NCC(=O)Nc1ncc(C#CCCO)s1 +Cc1noc(C2CCCN(Cc3ccn(C)c(=O)c3)C2)n1 +CC1Cc2ccccc2N1C(=O)CCc1nc2ccccc2s1 +Cc1cccc(Oc2ccccc2NC(=O)c2cnn(C)c2)c1 +O=C(c1ccccc1F)N1CC(OCc2ccc(F)cc2Cl)C1 +N#CC1(NC(=O)CCCNC(=O)c2ccc(F)cc2)CCCC1 +O=C(c1ccc(Cl)cc1)N1CCN(c2ccc(O)cc2)CC1 +N#Cc1c(NC(=O)COC(=O)C2CCC2)sc2c1CCCC2 +CC(c1ccc(F)c(F)c1)N(C)C(=O)COc1cccc(CO)c1 +CN(CCc1ccccn1)C(=O)c1cn2ccccc2n1 +CC(NC(=O)c1nn(-c2ccccc2)c2c1CCC2)c1ccncc1 +COc1ccc(CNC(=O)N(C)CCOc2ccccc2)cn1 +O=C(NCc1cccc(F)c1)c1ncccc1Cl +CCN(CC)C(=O)CN1CCN(C(=O)Nc2cccc(C)c2)CC1 +COc1ccc(COCC(=O)N2CCCC(c3ccn[nH]3)C2)cc1 +CC(=O)c1cc(C#N)c(SC(C(N)=O)c2ccccc2)nc1C +Cc1ccc(CN2CCOCS2(=O)=O)c2ccccc12 +COc1cccc(NC(=O)C2CCCN(C(=O)NC3CC3)C2)c1 +Cc1nn(-c2ccccc2)c(C)c1CCC(=O)N(C)c1ccccc1 +COc1cc(N)ccc1NC(=O)c1ccc(Br)cc1F +Cc1cc(CN2CCCC(c3nnc4n3CCC4)C2)c(C)o1 +CCn1c(=O)n(CC(=O)Nc2cccc(OC)c2)c2ccccc21 +COc1ccc(C(CNC(=O)Cn2ccnc2)N2CCOCC2)cc1 +COc1ccc(NC(=O)NCCN2CCOCC2)cn1 +COCCN(C)S(=O)(=O)c1ccc(N2CCCC2=O)cc1 +CC(C)(C)OC(=O)Nc1ccc(C(N)C(F)(F)F)cc1 +COc1cccc(-c2ccnc3c2c(=O)[nH]c(=O)n3Cc2ccco2)c1 +Cc1nc2ccc(NC(=O)c3ccccc3C)cc2o1 +Cc1ccccc1OC(C)C(=O)Nc1ccccc1C(N)=O +COC(=O)c1cncc(-c2cc(F)ccc2Cl)c1 +COCCOc1c(Cl)cccc1NC(=O)c1ccc(C(C)=O)cc1 +COc1ccc(-c2noc(CNC(=O)c3ccc(Cl)cc3)n2)cc1 +O=C(NC1CCN(C(=O)c2cnn3c2OCCC3)C1)c1ccsc1 +Cc1cc(C(=O)N2CCCCC2C(=O)NCC2CC2)no1 +CCOc1ccc(NC(=O)c2cccn2-c2cccnc2C)cc1 +O=C(NC1c2ccccc2CC1O)c1ccccc1Cl +Cc1ccc(C(=O)Nc2ccc(N)cc2Cl)cc1O +O=C1C(Sc2ccnc3ccccc23)CCN1C1CCOCC1 +COCCCC1CCCN(C(=O)c2cc(=O)c(OC)co2)C1 +O=C(NCc1ccc(F)cc1)c1c(F)cccc1F +CC(C)CCNC(=O)c1cc(S(N)(=O)=O)ccc1Br +O=C(NCCS(=O)(=O)N1CCc2ccccc2C1)c1ccco1 +COCCCOC1CN(C(=O)c2cn(C)nc2C(C)(C)C)C1 +CC(Cc1ccccc1F)C(=O)Nc1ccc(F)cn1 +COC(=O)c1cccc(NCC(=O)c2ccc(OC)cc2)c1 +COc1cccc(NC(=O)CNC(=O)c2ccccc2Cl)c1 +CC(C)NC(=O)CN1CCN(Cc2nc3ccccc3[nH]2)CC1 +CCOc1ccc(-c2nc(COC)c(C#N)s2)cc1 +CCN(CC)C(=O)CCC(=O)Nc1cc(Cl)c(N)c(Cl)c1 +O=C1CCC(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)CN1 +Cc1cc(C)n(CC(=O)Nc2cccc(N)c2C)n1 +CCN(CC(=O)Cc1ccccc1)CC(F)(F)F +COc1ncccc1C1NCCc2cc(C)cc(C)c21 +CCc1nnc(CSc2nc(-c3ccccc3)cn2N)o1 +COC(=O)c1cccc2c1CCCN2Cc1ccoc1C(=O)OC +C=CCN(Cc1cc(Br)ccc1F)Cc1cnnn1C +Cc1ccccc1NC(=O)CCNC(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CC1CCC(NC(=O)Cc2c[nH]c3ccccc23)CC1 +COc1ccccc1-n1cc(Cn2ccnc2-c2ccncc2)cn1 +Cn1ccnc1-c1nccn1CCCC1CCOC1 +CS(=O)(=O)c1cccc(-c2ccc(O)cc2F)c1 +COc1cccc(CN(C)C(=O)c2cc(C3CC3)nn2C(C)(C)C)c1 +Cc1ncccc1C(=O)N1CCN(Cc2ccccc2)C(C#N)C1 +O=C(NCc1ccsc1)NCc1cccs1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NCC2CCOCC2)n[nH]1 +CCC(C(=O)Nc1cccnc1)n1nnc(-c2ccc(Cl)cc2)n1 +CCc1n[nH]c(C2CCCN2S(=O)(=O)Cc2ccccc2)n1 +O=C(CCc1ccc(C(F)(F)F)cc1)N1CCCS1(=O)=O +COC(=O)C1CCCCN1Cc1coc(-c2cccc(F)c2)n1 +CCN(Cc1cccc(F)c1)C(=O)NCCN1CCOCC1 +CC(O)CN1CCN(CC(=O)NCc2ccc(Cl)cc2)CC1C +CC(=O)NC(C)c1ccc(C(=O)CSc2nnnn2C2CC2)cc1 +CCOc1ccc(C(=O)N2CCC(c3cccs3)CC2)cc1 +CC(O)c1ccc(S(=O)(=O)N2CCNC(=O)C2)cc1 +CS(=O)(=O)c1cc(F)c(N)cc1Br +COCc1nnc(SCc2ccccc2Cl)n1N +COC(=O)C1CCC(NC(=O)CCCc2cc(F)ccc2F)CC1 +CC1CC(=O)c2c(OCc3ccc(C(N)=O)cc3)ccc(Cl)c21 +CC(C)(O)CCc1cccc(C(=O)NC2CCC(O)CC2)c1 +Cc1cc(=O)n2nc(N(C)Cc3ccsc3)sc2n1 +C=CCCCN(C)C(=O)c1ccc(NC(=O)c2ccco2)cc1 +Cc1cccc(C(=O)OCC(=O)NCc2ccccc2)c1C +COc1ccc(O)c2c1C(c1cccs1)NCC2 +C#CCNC(=O)c1ccc(NC2CCCN(c3ncccn3)C2)nc1 +CC(=O)N(C)c1ccccc1C(=O)NCc1ccco1 +COc1ccccc1C(NC(=O)NCC(C)(C)O)C(C)(C)C +COc1ccc(-c2noc(-c3ccc(-n4cncn4)cc3)n2)cn1 +CCCC(C)NC(=O)c1sc(-c2cccnc2)nc1C +CC(C)CCNC(=O)N1CCN(C(=O)c2ccc(Cl)cc2)CC1 +O=C(CCN1CCN(C(=O)CC(F)(F)F)CC1)N1CCOCC1 +FC(F)(F)c1ccc(-n2nc(C3CC3)c3c2CCNC3)cc1 +CCCNC(=O)CS(=O)(=O)c1nncn1-c1cccc(Cl)c1 +COc1ccccc1C(=O)c1cncc2ccccc12 +COC(=O)C(NC(=O)c1cccc(Cl)c1N)C(C)C +CC(C)C(=O)NCc1ccc(-c2cccnc2)cc1 +Cc1ccc(CN(C)S(=O)(=O)c2ccc3c(c2)OCCO3)s1 +Cc1sc(=O)n(CC(=O)Nc2ccc3c(c2)COC3)c1C +CCOC(=O)C(N)Cc1nc2ccccc2n1CC +CC(C)C(=O)N1CCC(c2nc(CNC(=O)C3CCC3)cs2)CC1 +Cc1nn(C)c(=O)c(C(=O)Nc2ccc3c(c2)nc(C)n3C)c1C +O=C(c1cnc2ccccc2n1)N1CCC(c2nnc(C3CC3)o2)CC1 +CC(C)(C)c1nnc(NCc2cc(C(N)=O)cs2)o1 +CC(Oc1ccccc1)C(=O)NCc1ccc(Cn2cccn2)cc1 +Cc1csc(N2CCCC(c3nc4ccccc4o3)C2)n1 +COc1ccc(OC)c(-c2cc(C(=O)N3CCC(CO)C3)[nH]n2)c1 +Cc1ccc(CNC(=O)CSc2nc(=O)[nH]c3c2CCCC3)cc1 +CNC(=O)c1cc(C(=O)c2ccc(F)cc2Cl)c[nH]1 +NC(=O)C1CCCN1C(=O)C1C2CC3CC(C2)CC1C3 +O=S(=O)(Cc1ncc(CO)s1)c1ccc(Cl)cc1 +CCCNC(C#N)CCSc1nc2ccccc2[nH]1 +CC(C)NC(=O)c1sc2nc(-c3cccs3)ccc2c1N +CC(=O)NC(C(=O)Nc1nc2c(s1)CC(C)CC2)C(C)C +Cc1cc(-c2cc(C)nc(N3CCCCC3)n2)[nH]n1 +Nc1ccc(C(=O)NCc2ccccc2Cl)cc1 +CCCCS(=O)(=O)NCC(=O)c1cc(F)ccc1F +CC1CCCC1NC(=O)C1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +COC(C)C(=O)N1CCC(NC(=O)Nc2ccccc2)CC1 +Cc1cc(NCc2cccc(OCCCC#N)c2)ccc1F +CC(C)(C)c1ccccc1OCC(=O)OCc1nc(N)nc(N)n1 +O=C(Cn1c(-c2cccs2)cc2cccnc21)NC1CC1 +COC(=O)c1ccc(N)c(OCC(=O)N2CCCCCC2)c1 +Cc1cc(F)cc(-c2nc(C)c(CCO)s2)c1 +CCC(CO)N(Cc1ccc2nonc2c1)Cc1cccs1 +COCC(=O)N1CCN(C(C)C(=O)N2c3ccccc3CC2C)CC1 +CCOc1ccc(NC(=O)C2CC(=O)Nc3ncnn32)cc1 +CC(Sc1nnc(NC2CC2)s1)C(=O)c1ccc(F)cc1 +Cc1nnc(CNC(C)c2cnn(-c3ccc(F)cc3)c2C)s1 +O=c1c2ccccc2nc2n1-c1ccccc1OC2 +COc1cccc(-c2noc(Cn3c(=O)n(C)c4ccccc43)n2)c1 +CC(NC(=O)c1ccccc1)C(=O)NC(C1CC1)C1CC1 +O=C(NC1CCCc2occc21)c1ccccc1Br +Brc1coc2snc(-c3ccncc3)c12 +NC(=O)COC(=O)CSc1nnc(-c2ccc3ccccc3c2)o1 +O=C(NCc1cccnc1)c1ccc(-c2ccccc2)s1 +CCN1CC(C(=O)Nc2cccc3ccc(C)nc23)CC1=O +COc1c(C)cnc(Cn2cc(C(C)O)cn2)c1C +CS(=O)(=O)Nc1ccccc1CNC(=O)c1cccc(Cl)c1 +CC(C)NC(=O)N1CCCC(C(=O)N(C)c2ccccc2)C1 +COC(=O)CN(C(=O)Oc1ccccc1)C(C)C +CN(C)c1nc(N)nc(CN2CCCC2C(N)=O)n1 +Cc1ccc(-n2[nH]c(C(=O)NCCCn3cc(C)cn3)cc2=O)cc1 +CC(=O)NC(c1nnc(-c2nonc2N)o1)C(C)C +Cc1cc(C(F)(F)F)nn1C(C)C(=O)n1cccn1 +CCN(CC)C(=O)COc1ccc2oc(C)c(C(=O)OC)c2c1 +COc1cccc(-n2ccn(Cc3ccc(F)cc3)c(=O)c2=O)c1 +CCn1c(SCCC(=O)OC)nnc1-c1cccc(Cl)c1 +Fc1ccc(NCc2cccnc2)c(OC2CCCC2)c1 +COc1ccc(NC(=O)Nc2c(C)cccc2C)c(C)c1 +Brc1ccc(C2CN(Cc3ccco3)CCO2)cc1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)N(C)CC1CCCO1 +CC(=O)NC1(C(=O)Nc2ncc(C)s2)CCCCC1 +CC(Oc1ccccc1Cl)C(=O)Nc1cccnc1-n1cccn1 +Cc1cc(C)cc(OCCN(C)C(=O)CCc2[nH]nc(C)c2C)c1 +O=C(NCCOc1cccc(Cl)c1)c1n[nH]c(=O)[nH]1 +COC(=O)c1sc(NC(=O)c2csc(-c3ccco3)n2)nc1C +CC(C#N)Oc1ccc(CN(C)C(C)CC#N)cc1 +c1ccn2c(N3CCC4(CC3)OCCO4)nnc2c1 +Cc1ccc(NC(=O)CSc2nnc(CO)n2C2CC2)cc1C +COCCCNC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O +Cc1csc(=O)n1CC(=O)N(CCO)C1CCCC1 +CN(C)c1ccc(NC(=O)c2ccc(N3CCCC3=O)cc2)cn1 +O=C(Nc1cccc(C(=O)N2CCCC2)c1)N1CCOCC1 +O=c1cc(NCc2ccccc2)nc2n1CCCS2 +CC(C)(C)C(=O)CNC(=O)c1ccn(COc2ccccc2)n1 +CCOc1ccc(NC(=O)N2CCCC(C)C2CO)cc1 +CCOC(=O)c1cnn(-c2ccc(C(=O)NCC(C)O)cc2)c1C +FC(F)COc1ccc(-c2nc(C3CCCCC3)no2)cn1 +COc1cccc(C(=O)Nc2cccc(CN(C)C(C)=O)c2)c1O +CCN(CCC#N)C(=O)COc1cccc(C)c1F +O=c1oc(-c2ccco2)nn1Cc1ccn(-c2ccccc2)n1 +CNC(=O)NCC(=O)N(Cc1cccc(O)c1)CC1CC1 +O=C(Cn1cnc(NC(=O)c2ccccc2)n1)Nc1ccc(O)cc1 +OC1CCC(Nc2ncc(C(F)(F)F)cc2Cl)CC1 +CC(C)CC(O)c1cc(F)cc2c1NC(=O)C2(C)C +COc1ccc(NC(=O)C(C)S(=O)c2ccc(C)cn2)cc1 +CCC(CNC(=O)C1CC(=O)N(C)C1)Oc1ccccc1F +CN(CC(=O)OC(C)(C)C)Cc1ccc(Cl)cc1 +Cc1nc(-c2cnccn2)sc1C(=O)Nc1ccccc1 +O=C(CNC(=O)c1ccccc1OC(F)F)NC1CCCC1 +CCc1noc(CN(C)Cc2ccccc2-n2cccn2)n1 +C#CCNC(=O)c1ccccc1NCC(=O)NC(C)(C#N)C1CC1 +N#Cc1ccc(N2CCN(C(=O)N3CCCCC3)CC2)nc1 +CC(O)(CCc1ccccc1)CNC(=O)c1ccc(F)cc1 +Cc1ccc(C(=O)CCC(=O)Nc2ccc(-n3cnnn3)cc2)cc1 +c1ccc2c(c1)CCCN2c1ncnc2[nH]cnc12 +O=C(c1ccc(F)cc1)N1CCN(c2nnc3ccccn23)CC1 +CC(C)CCN(CCC#N)S(=O)(=O)c1ccc2c(c1)OCCO2 +N#CCCCCS(=O)(=O)c1nnc(NC2CCCCC2)s1 +CCn1nc(-c2cc(Cl)c(C)cc2OC)cc(N)c1=O +COC(=O)CC1CN(Cc2cc(Cl)c(OC)cc2Cl)CCO1 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)N1CCc2ccccc2C1 +CC(C)c1cc(C(=O)N2CCc3c(nc(N(C)C)[nH]c3=O)C2)no1 +COC(=O)NCCC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +Cc1nc2n(C)c3ccccc3n2c1C(O)CN1CCOCC1 +COCc1c(C(=O)Nc2cccc3cccnc23)oc2ccccc12 +O=C(Nc1cccc(-c2cn[nH]c2)c1)c1occc1Br +CCOC(=O)c1sc(NC(=O)C2CC2)nc1C +COc1ccc(F)c(-c2nc(CN3CCOCC3)c(C)o2)c1 +N#CC(C(=O)Cc1c[nH]c2cc(F)ccc12)c1nc2ccccc2s1 +CCC(CC)C(NC(=O)NCC(=O)N1CCCC1)c1ccccc1 +O=C(NCC1COc2ccccc2C1)c1ccc(-c2cnco2)cc1 +Cc1ccc(C(=O)NCC(=O)Nc2ccc(F)cc2F)cc1 +CC(C)NC(=O)c1nc(-c2cccc(C(F)(F)F)c2)no1 +CC1CN(C(=O)c2ccc(C(F)(F)F)nc2)CC(C)O1 +CC(C)CNc1ncnc2onc(-c3ccc(F)cc3)c12 +COc1ccccc1SCCn1cnc2c1c(=O)n(C)c(=O)n2C +CC(C)n1nnnc1CNC1CCCC1c1ccccc1 +CC(C)n1c(=O)[nH]c(=O)c2c(-c3ccc(F)cc3)ccnc21 +O=C(CCc1cccc(Cl)c1)NCc1ccoc1 +COc1cc(C(=O)CC(C)C)cc(OC)c1OC +CCC(=O)N1CCCC(C(=O)Nc2ccc3c(c2)COC3)C1 +CC(NC(=O)Nc1ccccc1OC(F)F)c1ccncc1 +CS(=O)(=O)N1CCN(CC(O)c2ccccc2Cl)CC1 +Cc1ccc(F)cc1C(=O)NCCCNc1ncccn1 +O=S(=O)(c1ccccc1)N1CC2CCC1C2Oc1cccnc1 +COC(=O)c1cccnc1NCc1cccnc1N +COC(=O)c1cc(Cn2ccc(=O)c3sccc32)c(C)s1 +CNC(=O)c1ccc(CNC(=O)Nc2ccccc2OC)cc1 +O=C(NCCCN1CCOCC1)Nc1ccccc1-c1ccccc1 +CCNC(=O)c1ccc(NC(=O)Cc2c[nH]c3ccccc23)c(C)c1 +COCCOc1ccccc1NC(=O)C1(C)CC1(Cl)Cl +CCn1cnnc1CNC(=O)C1CCN(c2ccc(C)cc2)C1=O +O=C(NCC1(O)CCOC1)c1ccc2ccccc2n1 +Cc1nn(C)c2sc(C(=O)NC3CCc4nnc(C)n4C3)cc12 +COc1ccc(CNC(=O)C2CCC2)cc1NC(C)=O +O=C(Nc1ccccc1C(F)(F)F)c1cn(Cc2ccccc2)nn1 +O=C(Nc1ccc(N2CCCCC2)c2ccncc12)c1ccc[nH]1 +CCn1ccc(NC(=O)c2ccc(OC(C)C)cc2)n1 +CNC(=O)N(CCc1ccccc1)Cc1cccnc1 +C=CCNC(=O)C1CCCN1c1nccc(C(F)(F)F)n1 +CCc1cc(=O)[nH]c2nnc(SCC(N)=O)n12 +CCCN1CCn2c(nc3cc(NC(=O)C(C)C)ccc32)C1 +CCCCS(=O)(=O)N1CCC(C(=O)Nc2ccnc(C)c2)CC1 +CCOC(=O)C1CCN(C(=O)Nc2cccnc2OCC)CC1 +Cn1cccc(NC(=O)C2CCCN2C(=O)c2cccs2)c1=O +O=c1oc2ccccc2n1Cc1cc2c(cc1Br)OCO2 +CC(=O)NC1C(O)OC(COC(C)=O)C(OC(C)=O)C1O +CCn1ccc(NC(=O)Cc2ccc(OCc3nnnn3C)cc2)n1 +Cc1ncsc1CNC(=O)NCCNC(=O)CC1CCCC1 +COc1ccsc1S(=O)(=O)Nc1c(C)n[nH]c1C +CSc1ccc(C(=O)N(Cc2ccncc2)C2CC2)cc1 +NC(=O)c1ccc(CNc2ccccc2C(F)(F)F)cc1 +CCOC(=O)c1c(NC(=O)c2ccnn2CC)sc2ccccc12 +COc1ccc(-c2cc(C(=O)Nc3cccnc3)no2)cc1 +O=C(Nc1c[nH]ccc1=O)c1ccccc1-n1cnnn1 +CN(CCC#N)C(=O)Nc1ccc(F)cc1OCC(F)(F)F +CC#CCSc1nnc(Cc2cccs2)o1 +CC(=O)c1cc(C)ccc1OC(C)C(=O)NC(C)C +CC1(NC(=O)CCNC(=O)Cc2ccccc2)Cc2ccccc2C1 +Cn1nc(C(=O)Oc2ccccc2Br)ccc1=O +CCN(CC)C(=O)c1ccc(-c2ccc3c(c2)OCCO3)s1 +Cc1nc(C2CCN(C(=O)c3nn(C)cc3Cl)CC2)cc(=O)[nH]1 +COc1ccc(CNc2ccc(C#N)cc2)c(Br)c1O +CC(=O)Nc1ccc2c(c1)C(c1c(C)ncnc1C)NCC2 +Cc1noc(C)c1CC(=O)Nc1ccc(Cl)c(F)c1 +CCC(Oc1ccc(N)cc1F)C(=O)OC(C)C +O=C(Nc1ccc2c(c1)CCN2C(=O)c1cccnc1)c1ccncc1 +COCCOc1ccccc1NC(=O)C1CC(=O)N(C2CCCC2)C1 +COC(=O)Nc1cccc(C(=O)N(C)C2CCc3ccccc3C2)c1 +Cc1noc(C)c1C(C)NS(=O)(=O)c1cccc(Cl)c1 +COc1ccc(-c2nnc(SCc3cccnc3)o2)cc1 +O=C(NCCc1ccc(-n2cccn2)cc1)c1csnn1 +Cn1c(CCC(=O)OCc2ccccc2)nc2ccccc2c1=O +COc1cc(C)c(-c2nc3sc(C4CC4)nn3c2C#N)c(C)c1 +COc1cc(OC)c(C(=O)OCC(=O)N2CCOCC2)cc1OC +COc1cc2c(cc1OC)CCN(C(=O)c1ccc(C)s1)CC2 +O=C(NCCOc1ccc2c(c1)OCO2)c1ccn2ccnc2c1 +CSc1cccc(NC(=O)Cn2ccc3sc(C)cc3c2=O)c1 +c1ccc(-c2nc3cnccn3c2NCc2ccc3c(c2)OCO3)cc1 +Cn1cc(C(=O)Oc2cccc(C(N)=O)c2)c(C(F)(F)F)n1 +Cc1nn(C)c(C)c1CNC(=O)C1CCC(=O)N1Cc1ccco1 +Cc1cnc(NCc2nc3c(s2)CCC3)s1 +Cc1cccc(Oc2ccc(NC(=O)NC(C)CO)cc2)c1 +CC(C)N(Cc1cccnc1)C(=O)Nc1ccccc1F +COc1cc(NC(=O)N2CCCC(C)C2)ccc1N1CCOC1=O +O=C(COC(=O)c1ccccn1)Nc1cc(Cl)cc(Cl)c1 +CC(C)Oc1nccnc1N1CCN(c2ccccc2O)CC1 +CCCN1C(=O)NC(c2ccncc2)C(C(=O)OCC)=C1CC +Cc1ccc(-c2nnn(C(C)c3nc(N)nc(N(C)C)n3)n2)cc1 +O=C(NC1CC1)c1cccc(-c2cc(N3CCCC3)ncn2)c1 +Cc1nc(-c2cccc(NC(=O)N(C)CC3CCCCO3)c2)oc1C +COc1ccc(-c2nnc(CNc3c(C)cccc3C(N)=O)o2)cc1 +O=C(Nc1ccc(Cl)cc1F)C1CC(=O)N(Cc2ccco2)C1 +COc1ccc(NC(C)=O)cc1NS(=O)(=O)c1cccc(F)c1 +Cc1cc(C)c(C)c(OCCc2ncc(CO)s2)c1 +CC(=O)c1cc2c(cc1NC(=O)C1CC(=O)N(C)C1)OCO2 +Cc1cc(CN(C)C(=O)C2(c3ccccc3)CCOCC2)no1 +CCc1cccc(C)c1NC(=O)N1CCC(N2CCOC(C)C2)CC1 +c1ccc(COc2ccc(-n3cncn3)cc2)nc1 +C=CCn1ncc(-c2nc3c(C)nn(-c4ccccc4)c3[nH]2)c1C +CCCCC(=O)Nc1cnc(NC(=O)c2cccs2)cc1C +CN(Cc1ccc(C#N)cc1)C(=O)c1ccsc1 +C=C(C)COc1ccccc1C(=O)N1CCCC1COC +CC(Sc1nnc(-c2cccnc2)n1C)C(=O)Nc1ccccc1 +COC(=O)c1ccc(C(=O)NCC#Cc2ccccc2OC)cc1 +Cn1cc(C(=O)Nc2cc(F)ccc2Cl)ccc1=O +COC(=O)c1ccc(COCCc2scnc2C)cc1 +COc1ccc(S(=O)(=O)Nc2cc(OC)ccc2OC)cc1 +Cc1nn(CCC(=O)N2C(C)CCCC2C)c(C)c1Br +NC(=O)CCCNC(=O)c1ccc(C(F)(F)F)nc1 +Cc1csc(C(=O)N2CC(S(=O)(=O)c3ccc(F)cc3)C2)c1 +COCc1ccccc1NC(=O)c1ccc(-c2ccsc2)nc1C +Fc1ccc2sc(NCC3CCCCO3)nc2c1 +COC(=O)C(C)NC(=O)C12CC3CC(CC(C3)C1)C2 +CC(Cn1ccnc1S(C)(=O)=O)C(=O)c1ccc(F)c(F)c1 +O=C(NC(c1ccccc1)c1ccccn1)c1cc(-c2ccco2)on1 +CC(C)(C)C(=O)NCC(=O)N1CCOCC1C1CC1 +Nc1nc(=O)[nH]c2c1cnn2-c1ccc(Cl)cc1 +Cc1nnsc1C(=O)NC(C)C12CC3CC(CC(C3)C1)C2 +COc1cc(NCc2ccc3c(c2)OCCCO3)ncn1 +CCC(=O)N1CCc2nc(N3CCCC3)nc(C)c2CC1 +CCOc1cc(F)ccc1NCC(=O)Nc1ccc2c(c1)OCCO2 +CC(C)(C)OC(=O)N1CCN(c2ccc(C#N)c(F)c2)CC1 +O=C(Nc1ccc(CC(=O)N2CCCC2)cc1)c1ccc2cncn2c1 +CCCCn1nc(C(=O)N(CC)Cc2cccc(F)c2)ccc1=O +Cc1cccc(NC(=O)CC2COc3ccccc3NC2=O)c1C +CC(C(=O)NCc1ccccn1)n1nc(-n2cccn2)ccc1=O +Cc1cc(=O)n(CC(=O)NCc2ccco2)c2c(C)cccc12 +NC(=O)c1ccc(C(=O)Nc2ccccc2Cl)cc1 +CC(C)c1ccc(-n2nnnc2SCC(=O)NC(C)C2CC2)cc1 +Cc1nn(C)c(C)c1NC(=O)CS(=O)(=O)c1ccc(Cl)cc1 +Fc1cc2c(cc1F)C(c1cnccc1Cl)NCC2 +Cc1csc(N2CCN(CCOc3ccccc3)CC2)n1 +O=C(CC1(O)C(=O)N(Cc2ccccc2)c2ccccc21)c1ccco1 +CN(C)C(=O)CCOc1cccc(Br)c1 +Cc1cc(OCC(=O)N2CC(C)OC(C)C2)ccc1Cl +CCCC(C)(C)NS(=O)(=O)c1ccc(S(C)(=O)=O)cc1 +O=C(NCCSc1ncccc1Cl)OCC(F)(F)F +CC(NC(=O)c1ccc(-n2ccnn2)cc1)c1cnn(C)c1 +CC(NC(=O)NCc1cc[nH]n1)c1ccc2c(c1)CC(=O)N2 +O=S(=O)(c1c[nH]cn1)N1CCN(C2CC2)CC1c1ccccc1 +Cc1ccc(S(=O)(=O)NC(C)(C)C)c(C#CCO)c1 +COc1cc(CC(=O)N2CCC(CC(N)=O)CC2)ccc1C +CCN(CC)C(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 +CCn1c(C)cc(C(=O)NCc2nc3ccccc3s2)c1C +COc1cc(CN(C)C(=O)c2ccc(F)cc2)ccc1O +CCOC(=O)c1cc(-c2ccc(Cl)cc2)n[nH]1 +CCCCOC(=O)C(C)Sc1nc(C)cc(N)n1 +Cc1ccccc1-c1nnn(CC(=O)N2CC(C)OC(C)C2)n1 +CCOCCn1c(=O)c2c(OCC)c(C)cnc2n(C)c1=O +CCCc1cc(=O)n(CC(=O)Nc2ccccc2OC)cn1 +Cc1sc(-c2nnc(C(C)C)o2)cc1NS(C)(=O)=O +COc1ccc(C(=O)N(C)Cc2cccs2)c(F)c1 +CCOc1ccc(Nc2ncnc3c2nnn3CC)cc1 +C=CCn1c(C)cc(C(=O)COc2ncnc3sccc23)c1C +O=C(C1CC1)N1CCN(Cc2ccccc2Cl)CC1 +CCc1noc(CC)c1CC(=O)N(C)Cc1nc2ccccc2n1C +CN(CC(=O)N1CCCC1)C(=O)Cc1csc(-c2ncccn2)n1 +Cc1ccc(NC(=O)CC2CCCC2)cc1NC(=O)c1ccncc1 +O=C(NCc1ccccn1)c1ccc(F)cc1-n1cnnn1 +COC(=O)CCn1c(S(C)(=O)=O)nc2ccccc21 +CNC(CC(=O)OC)C(=O)c1ccc(OC)cc1C +O=C(NCCc1csc(N2CCCC2)n1)Nc1ccccc1 +NC(=O)c1ccc(CNc2ccc(F)c(F)c2F)cc1 +COc1ccc(O)c(C(=O)NCCCC(N)=O)c1 +Cc1c(NC(=O)c2cc(=O)[nH]c3ccccc23)cccc1-n1cnnn1 +COc1cccc(C(=O)OC(c2cccc(F)c2)c2ccccn2)n1 +O=C(c1csnn1)N1CCC2(CC(Nc3ncccn3)CO2)C1 +N#CC(CCC(=O)N1CCCC1)c1ccc(F)cc1 +COc1cc(C#N)ccc1OC(C)C(=O)NCc1ccc(Cl)cc1 +CC(=O)NC(C(=O)Nc1ccc(C(=O)NC2CCCC2)cc1)C(C)C +COC(=O)CN(C(=O)Cn1ncc(=O)c2ccccc21)C(C)C +CCN(Cc1ccoc1)C(=O)NC(C)c1cc(OC)c(OC)cc1C +COC(=O)c1c(NC(=O)C2CCCC2)c(C)nn1C +Cc1nnc(SCC(=O)NC(C)c2ccccc2)n1N +Cc1noc(C(C)NC(=O)CCc2ccccc2Cl)n1 +Cc1cnn(C)c1C(=O)Nc1nc2c(C)cccc2s1 +Cc1csc(N2CCN(CC(=O)NC(C)c3ccco3)CC2)n1 +O=C(CCc1ccc(Cl)cc1)NCCNC(=O)c1ccc(O)cc1 +CCCn1c(C)nnc1SCC(=O)c1ccc(NC(N)=O)cc1 +Cc1n[nH]cc1CNc1cccc(-c2cnco2)c1 +O=S(=O)(c1cccc2cccnc12)N1CCC(n2cccc2)CC1 +CC(CCc1ccco1)NC(=O)NCCc1ccccc1 +CC(=O)Nc1ccc(OC(=O)Cn2nc3n(c2=O)CCCCC3)cc1 +COC(=O)c1ccc(Cn2c(=O)oc3ccccc32)cc1F +CCCC1CN(C(=O)Nc2cc(C3CCC3)nn2C)CCO1 +Cc1cccc(S(=O)(=O)Cc2nc(-c3ccco3)no2)c1 +CN(C)c1ccccc1NC(=O)Nc1cnn(CC2CCCO2)c1 +C=CCn1c(SCC(N)=O)nnc1-c1ccccc1C +O=C(COc1nncc2ccccc12)Nc1ccc(OC(F)F)cc1 +Cc1cccc(N2CCN(C(=O)c3ccc(=O)n(C)c3)CC2)c1C +Cc1sc2ncnc(Sc3nc4ncccn4n3)c2c1C +Cc1cc2c(=O)n(CC(=O)c3ccc4ccccc4c3)cnc2s1 +CCN(CC)S(=O)(=O)c1ccc(NC(=O)c2cccnc2)c(C)c1 +Cn1nc(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)ccc1=O +CC(C)c1ccc(-c2cc(C#N)nn2CCCO)cc1 +COC(=O)c1ccc(NC(=O)Cn2nnc3ccccc32)c(F)c1 +O=C(N1CCOCC1)N1CCc2ncnc(NC3CCC3)c2CC1 +O=C(NCc1ccncc1)c1ccc(C(=O)NCc2ccncc2)cc1 +Nc1nccnc1C(=O)Nc1cccc2cccnc12 +CCn1c(C)c(C(=O)NCc2ccncc2)c2cc(OC)ccc21 +COc1cc(CNc2cccc(OC(F)F)c2)cc2c1OCCO2 +O=C(NCCc1cc(F)c(F)c(F)c1)N1CCCC(CO)C1 +O=C1C(N2CCOC3(CCCC3)C2)CCN1C1CC1 +Cc1cccn2cc(CNC(=O)c3cnc(C4CCCO4)s3)nc12 +C#Cc1cccc(NC(=O)CCOCC2CCCO2)c1 +CN(Cc1ccsc1)S(=O)(=O)c1cccc(Cl)c1Cl +NC(=O)C(NCc1ccccc1Cn1cccn1)c1ccccc1 +O=C(NC(CN1CCCC1=O)c1ccccc1)c1csnn1 +CNC(=O)NCC(=O)Nc1ncc(C(C)C)s1 +CCN(C(=O)COc1ccc(C)cc1OC)c1ccccc1 +Cc1ccc(S(=O)(=O)NCc2cn3c(C)csc3n2)cc1 +Cc1ccc(OC(=O)COc2ccc(CC(N)=O)cc2)cc1 +CCOc1ccc(C)cc1-c1cn2cc(CO)ccc2n1 +Cc1cccc(C)c1NC(=O)NCc1ccccc1 +CN(C)c1ncccc1C(=O)Nc1nc(C(C)(C)C)cs1 +CCS(=O)(=O)N1CCCC1c1ccccc1C +COc1cccc(-c2nnn(CC(=O)NCC3CCCO3)n2)c1 +O=C1CC(CNS(=O)(=O)c2cccnc2)CN1c1ccc(F)cc1 +NC(=O)NCC(=O)NCCCOC1CCCCC1 +Cc1cccc(C)c1NC(=O)CSc1nnc(C2CC2)o1 +COC(=O)c1cccc(CCNC(=O)CC(F)(F)F)c1 +Cc1cc(NC(=O)NCC2(c3ccc(F)cc3)CCCC2)n(C)n1 +COc1cccc(NC(=O)NCC(O)c2sccc2C)c1 +O=C(NCc1ccccc1)c1cnc2sc3c(n2c1=O)CCCC3 +CCOc1cccc(OCC(CC#N)N2CCOCC2)c1 +COC(=O)CCCOc1ccc(F)cc1Br +Cc1n[nH]c(O)c1C(c1cccc(Cl)c1)c1c(O)n[nH]c1C +COc1ccc2[nH]c(-c3cc(-c4cc[nH]c4)nc(N)c3C#N)c(C)c2c1 +NC(=O)c1ccc(C(=O)NCCc2c[nH]c3cc(F)ccc23)cc1 +COCCNC(=O)Nc1ccc2c(c1)N(C(C)=O)CC2 +CCNC(=O)CN1CCN(C(=O)c2cccc(C)c2O)CC1 +Cc1csc(C(C)NCc2ccc(F)c(C#N)c2)n1 +O=C(NCCC1CCCO1)N1CCCC(c2nc3ccccc3o2)C1 +Cc1nnnn1-c1ccc(CC(=O)Nc2cnc3n2CCCC3)cc1 +Cc1cccc(OCC(C)NC(=O)c2cnn(C(C)(C)C)c2)c1 +CCCc1nc(C(=O)NCCCc2ccc(O)cc2)cs1 +CC(=O)c1cccc(NCCCCc2cccc(N)c2)c1 +CC(=O)Oc1ccc(C(=O)Nc2ccc(C)c(F)c2)cc1 +CN(Cc1cscn1)c1ccc(Cl)cc1C#N +Cc1noc(C(C)OC(=O)Cc2c(F)cccc2F)n1 +Cc1ccc(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)cc1 +CN(C)C(=O)N1CCc2ncnc(-c3ccoc3)c2CC1 +CC(=O)c1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1 +COc1cccc(C(C#N)NCc2ccccc2F)c1 +CC(C)c1ccc(C(=O)NC2CCCCC2)c(N)n1 +CC(C)C(C(=O)NC(C)(C)C)n1cnc2c1c(=O)n(C)c(=O)n2C +O=C(OCc1noc(-c2ccc(F)cc2)n1)c1ccsc1 +CCOC1CCCN(C(=O)c2c(F)cc(Br)cc2F)C1 +CCOc1ccc(-c2ncc(C#N)s2)cc1OCC +NC(=O)COC(=O)c1csc(-c2ccsc2)n1 +CNC(=O)Cn1nnc(S(=O)(=O)c2ccccc2)c1N +O=C(NCc1nc(-c2ccccn2)no1)c1ccc(C(F)(F)F)cc1 +CCN(CCO)S(=O)(=O)N(C)Cc1ccccc1 +Cc1noc(C)c1CC(=O)Oc1ccc2c(c1)CCC2 +O=C(Nc1ccncc1Br)c1ccccn1 +CC1CCCN(C(=O)c2cc(Cl)c3c(c2)OCCCO3)CC1 +COC(=O)CCS(=O)(=O)N(C)c1ccc(C#N)cc1 +CCC(C)NC(=O)C(C)NC(=O)NCC1CCC1 +O=C(NCCNC(=O)c1c(F)cccc1F)c1cc(Cl)ccn1 +Cc1cc(N2CCNC(C)C2=O)ccc1Br +Cc1ccccc1C1CC(c2cccnc2)=Nc2ncnn21 +CCCCN(C)C(=O)Nc1ccc(NC(C)=O)cc1C(F)(F)F +Cc1nn(C)c2ncc(NC(=O)c3cccc(F)c3)cc12 +Cc1ccc(NC(=O)N2CCOC3(CCOCC3)C2)cc1C +CCCOc1ccccc1NC(=O)N(CC)CC +CSc1cc(C(=O)N2CCOCC2C2CC2)ccn1 +CCN(CC)C(=O)C(C)N1CCN(C(=O)c2ccco2)CC1 +CCOC(=O)c1coc(N2CCC(C(O)CC(C)C)CC2)n1 +CCOC(=O)CN(c1cccc(F)c1)S(C)(=O)=O +COc1cc(C(C)=O)ccc1OC(=O)CCc1cc(F)ccc1F +Cc1occc1C(=O)NCC(=O)N1CC(C(C)C)Nc2ccccc21 +Cc1cnc(C(=O)OCC(=O)N(C)Cc2cccc(F)c2)cn1 +CCNC(=O)CCCC(=O)NC1(C)Cc2ccccc2C1 +COCCCNC(=O)CCn1c(=O)c2cccn2c2cccnc21 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccsc1 +Cc1cnn(CCC(=O)NC(c2ccccc2)c2ccccn2)c1 +O=C(NCc1ccc(=O)[nH]c1)c1cc(N2CCCC2=O)ccc1Cl +CCNC(=O)CN(CC)S(=O)(=O)c1ccc(C)c(C)c1 +Cc1cc(NC(=O)c2cnc(C3CCCO3)s2)ccc1OC(C)C +CCc1c(C(=O)N2CCC3(CC2)CN(C)C(=O)O3)csc1C +CN(CCO)C(=O)Nc1ccc(Cl)c(Br)c1 +COCCNC(=O)C1(CC(=O)Nc2ccc(C)cc2)CCCC1 +COc1cc2c(cc1OC)C1=NCN(CCCOC(C)C)C(=O)C1=N2 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)c1cccc(Cl)c1 +CC(NC(=O)CCc1nc2ccccc2[nH]c1=O)c1ccc(F)cc1 +CC1(C)C(NC(=O)NC2CC2c2c(F)cccc2F)C2CCOC21 +Cc1nc(SCC(=O)N2CCOCC2)c2c3c(sc2n1)CCC3 +Cc1ccc(NC(=O)NCC(=O)NCC2CC2)cc1Br +Cc1ccc(S(=O)(=O)Nc2cnccc2C)cc1 +CC(Oc1ccc(F)c(F)c1)C(=O)NCC(F)(F)F +CC(NC(=O)c1ccc2c(c1)COCO2)C(O)Cc1ccccc1 +OC(CN1CCOC(c2nccs2)C1)c1ccc2ccccc2c1 +CCCNC(=O)c1ccc2c(c1)SCC(=O)N2 +C=CCOc1ccc(C=c2sc3ncnn3c2=O)cc1 +CCCCc1nnc(NC(=O)c2sc(C)nc2C)s1 +CCCCc1nnc(NC(=O)c2cnc(C)cn2)s1 +Cc1ccc(C)c(CC2Oc3ccc(N)cc3N(C)C2=O)c1 +CC(C)c1ccccc1NC(=O)NCc1ccccn1 +N#Cc1ncn(CC(=O)Nc2ccc3c(c2)OCCCO3)n1 +CCS(=O)(=O)NCC1Cn2nnc(-c3ccccc3)c2CO1 +CNC(=O)C1Cc2ccccc2N1C(=O)Nc1ccccc1OC +CCOc1ncccc1C(=O)Nc1c(C)cc(Br)cc1C +Cn1cc(C(=O)N(Cc2ccccn2)c2ccc(F)cc2)ccc1=O +CCCOc1cc(C)ccc1NC(=O)N1CCCC1c1nncn1C +CCOCC1CCN(C(=O)Nc2c(C)noc2CC)CC1 +CN(Cc1ccccc1F)C(=O)CN1CCOC2CCCCC21 +COCC(O)CN(C)C(=O)C(C)Sc1ccccc1 +COc1cc(CC(=O)N2CC3C4CCC(C4)C3C2)cc(OC)c1OC +O=C(CCc1nc(-c2cccnc2)no1)NC1CCCCCC1 +Nc1cc(F)cc2c(C(=O)Nc3cccc(O)c3)nccc12 +CC(C)C(C)NC(=O)CCC(=O)c1ccc(Br)cc1 +CCC1CCCN(C(=O)c2ccc(Cl)c(N)c2)C1 +O=C(C1CC1)N1CCCC1Cn1nnc2ccccc21 +CN(C)c1ncccc1NC(=O)c1cc(Cl)ccc1Cl +COc1cc(OC)c(C(=O)CN2CCOCC2)cc1Cl +CC(=O)N1CCc2ccccc2C1CC(=O)NC(C)(C)CC(C)(C)C +Cc1cc(N2CCC(O)(c3cccnc3)CC2)n2nc(C)c(C)c2n1 +COc1c(Br)cccc1CCNC(=O)c1ccoc1 +Cc1ccc2cccc(Oc3ncnc(N4CCCCC4C)c3N)c2n1 +O=C1CCCc2cc(C(O)c3ccc(F)cc3)ccc2N1 +COc1ccc(CCNc2nc3c(c(=O)[nH]2)CCC3)cc1 +CC(=O)N1Cc2ccccc2CC1C(=O)N1CCNc2ccccc2C1 +COc1ccc2nc(C)c(C(=O)OCc3c(C)noc3C)cc2c1 +N#Cc1cnn(C(=O)Cc2ccc(Cl)c(Cl)c2)c1N +Cc1ccc(C2CC(=O)Nc3cc4c(cc32)OCO4)cc1 +CCOc1ccc(CN(C)C(=O)c2ccccn2)cc1 +COc1cccc(N2CCN(C(=O)NCCc3cnn(C)c3)CC2)c1 +O=C1CC(C(=O)N2CCCCC2Cn2cccn2)CN1C1CC1 +COC(C)(C)c1noc(-c2cccc(-c3n[nH]c(C)n3)c2)n1 +CCOc1ccc(C(=O)Nc2cccc(O)c2)cc1OCC +CC(C)(C)OC(=O)N1CCN(C(=O)CNc2cccc(C#N)c2)CC1 +Cn1nnc2c(NCCc3ccc(F)cc3)ncnc21 +Cc1cccc(NC(=O)c2ccc3ccccc3n2)n1 +N#Cc1cc2c(nc1N1CCC3(CC1)OCCCC3O)CCCC2 +CCn1c(C)cc(C(=O)Cn2nc(-c3ccc(F)cc3)oc2=O)c1C +CCc1ccc2c(c1)S(=O)(=O)N=C(NCCC(C)C)N2 +Cn1cccc1C(=O)OCCC1CCCCN1C(=O)c1cccn1C +CCOC(=O)CCNC(=O)c1cc(Cl)cc(Cl)c1 +CC(C)(Br)C1NCCc2cc(O)ccc21 +CC(=O)c1ccc(NC(=O)NCCC(F)(F)F)cc1C +Cc1csc(C(OC(=O)C2CCC2)C(F)(F)F)n1 +Nc1cc(F)cc(S(=O)(=O)NC2CCCCC2O)c1 +C=CCNc1ncnc2sc(C(=O)NCc3ccon3)c(C)c12 +COc1ccc(Br)cc1S(=O)Cc1ncc(C)o1 +CN(C)S(=O)(=O)NCCCNC(=O)c1ccc(F)cc1 +CN(C)C(=O)c1ccc(C(=O)N=c2[nH]c3ccccc3[nH]2)cc1 +COc1ccc(C(=O)Cn2cnc(C#N)n2)c(OC)c1 +CCC(CC)N(C)C(=O)Nc1ccc(C)c(S(=O)(=O)NC)c1 +Cc1ccc(S(=O)CC(=O)Nc2cc(Cl)ccc2Cl)nc1 +COc1cccc(C2CC(O)=Nc3c2ncn3-c2ccccc2)c1OC +O=C(c1ccc[nH]c1=O)N1CCN(c2ccc(Cl)cn2)CC1 +CC(C)CC(CO)NS(=O)(=O)c1ccc2c(c1)OCO2 +Cc1csc(N2CCN(Cc3cn4ccsc4n3)CC2C)n1 +COc1ccc(OCCn2c(C(C)O)nc3ccccc32)cc1 +CC(=O)NCCC(=O)Nc1cc(C(N)=O)ccc1C +CCC(NC(=O)NCc1nnc2n1CCC2)c1ccccc1OC +C1CCc2nnc(-c3nnc4n3CCCCC4)n2CC1 +C#CCNC(=O)CNC(=O)Nc1ccc(N2CCOC2=O)c(OC)c1 +Cc1cc(S(=O)(=O)N(C(C)C)C2CCC2)ccc1F +CC(C)N(CC(F)(F)F)C(=O)Cn1cnc2ccccc2c1=O +O=C(Nc1ccccn1)c1ccc(Cn2cnc3ccccc3c2=O)o1 +Cc1cc(C(=O)CSc2nncn2C)c(C)n1-c1nccs1 +CCn1c(C(=O)Nc2c[nH]ccc2=O)cc2ccccc21 +Cn1c(CCNC(=O)c2cnn3ncccc23)nc2ccccc21 +Cc1ccc(CNC(=O)c2n[nH]c(=O)c3ccccc23)cc1 +CC(O)c1ccc(CNC(=O)Nc2ccc(F)cc2F)cc1 +CC(=O)Nc1ccc(C(=O)NCc2nc(C(C)(C)C)cs2)cc1 +CCc1nn2c(=O)cc(COC(=O)C(C)C)nc2s1 +Cc1cccc(C)c1NC(=O)Cn1nc2c(cc1=O)CCCC2 +COc1ccc(OC)c(S(=O)(=O)Nc2ccc(C)cn2)c1 +CCOCC(=O)Nc1cccc(OC2CCCC2)c1 +CN(C(=O)CCNC(=O)C(C)(C)C)C1(C#N)CCC1 +COc1ccc(C(=O)Nc2ccc3c(c2)CCN3C(C)=O)c(O)c1 +CC(C)c1cc(NC(=O)CS(=O)(=O)c2ccccc2F)on1 +CC(=O)Nc1nc2c(s1)CN(C(=O)c1ccc(=O)n(C)n1)CC2 +Cc1cc(F)ccc1NC(=O)CCC(=O)c1cccs1 +COC(=O)N1CCCC(c2nnc(Cn3ccnc3)n2C)C1 +Cc1cccc(N2CCN(C(=O)c3cncnc3C(C)C)CC2)c1 +CCN(CCO)C(=O)c1cc(-c2ccccc2)nc2onc(C)c12 +CCCCc1nn2c(=O)cc(COC(C)=O)nc2s1 +Cc1n[nH]c(SCn2nnc3ccccc3c2=O)n1 +NC(=O)c1oc2ccccc2c1NC(=O)Cc1cccc2ccccc12 +CCNC(=O)c1ccc(N)c(OCc2ccc(F)cc2)c1 +CC1(C)COC(c2cccn2Cc2ccc(F)cc2)=N1 +COC(=O)N1CCC(CNC(=O)c2ccc(C#N)cc2)CC1 +COCCOc1ccc(NC(=O)C2CCCC2)cc1 +COC(=O)c1ccc(OCC(=O)OC(C)(C)C)cc1 +Cc1cccc(OCC(=O)Nc2onc3c2CCCC3)c1 +Cc1ccc(C(C)NC(=O)c2ccc(=O)n(Cc3ccccc3)n2)o1 +CCCNC(=O)CNC(=O)Nc1ccccc1N(C)C +Cc1cc(C(=O)N2CCC(F)(F)CC2)c2cc(Cl)ccc2n1 +CCC(NC(=O)COc1ccc(C)c(C)c1)c1ccccc1 +CCCCn1nc(C(=O)Nc2cc(C#N)ccc2Cl)ccc1=O +CCCc1ccc(NS(=O)(=O)c2cn[nH]c2)cc1 +CSc1ccc(OC(=O)c2csc(NC(C)=O)n2)cc1 +Cc1nnnn1-c1cc(NCc2noc(CC(C)C)n2)ccc1F +COc1cccc(C2CC2C(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +Cc1ccccc1NC(=O)COC(=O)c1cc(-c2cccnc2)on1 +CCC(=O)Nc1ccc2c(c1)cc(C(=O)NCc1ccco1)n2CC +N#Cc1ncn(Cc2cc(-c3ccccc3)no2)n1 +CCNc1ncc(S(=O)(=O)N(C)CC(F)(F)F)cn1 +CCN(CC)c1ncnc(Nc2ccccc2OC)c1N +CCC(CC)(CO)NC(=O)c1ccc2c(c1)CCO2 +O=C(C1CC1)N1CCOC(COc2ccccc2F)C1 +COCC(C)NC(=O)COc1cccc(C)c1N +Cc1cc(Br)ccc1C(=O)N1CCCC(NC(N)=O)C1 +CCCCC1(C)C(=O)N(CC)c2cc(N)ccc2N1C +CC1CCCCN1c1ncnc(N2CCc3ccccc3C2)c1N +Cc1cc(O)ccc1NC(=O)c1ccccc1Br +O=C(CCOCC1CCCO1)Oc1ccc2cn[nH]c2c1 +CCC(=O)c1ccccc1OS(=O)(=O)c1ccccc1F +NC(=O)c1ccc(NC(=O)c2ccc(O)cc2)cc1 +COc1cc(NC(=O)Cc2cccc(F)c2)cc(OC)c1 +CCOc1cc(NC(=O)CCc2c(C)nn(C)c2C)ccc1OC +Cc1csc(C(C#N)C(=O)c2ccc(OCc3ccccc3)cc2)n1 +CCCN(Cc1ccc(C#N)cc1)C(=O)CNC(=O)c1ccccc1C +CCCn1nc(C(=O)Nc2cc(Cl)ccc2O)ccc1=O +COc1ccc2[nH]cc(CCNC(=O)c3ccccc3C(C)=O)c2c1 +CCC(C)NC(=O)Cc1csc(NC(=O)OC)n1 +CCN(CC(F)(F)F)C(=O)c1nc(N)ccc1Cl +CCc1ccccc1CNC(=O)c1ccc(S(N)(=O)=O)cc1 +COCCOC(=O)c1cnc(-c2ccccc2)s1 +COC(=O)c1ccccc1NC(=O)c1cc(N)ccc1Cl +COc1ccc(C)cc1CNC(=O)c1ccn(C)c(=O)c1 +O=C(CCCNc1ncccn1)N1CCN(Cc2ccccc2)CC1 +Cc1nc2sc(CNC(=O)c3ccccc3)nn2c1CO +NC(=O)c1ccccc1Oc1c(N)cccc1Cl +CN(Cc1nnc2ccccn12)C(=O)c1cccc2ccccc12 +Cc1cccc(C)c1OCC(=O)N1CCC(CO)C1 +NC(=O)c1c(F)cccc1-n1cnc(-c2ccccc2)c1 +CCOC(=O)C1=C(CC)Nc2ccccc2N=C1NC(=O)CC +CCC(CO)NC(=O)CN1CCN(c2ccccc2OC)C1=O +Cc1cc(NC(=O)c2cc(-c3ccc(F)cc3)n[nH]2)sn1 +O=c1ccc(-c2noc(-c3nccc4ccccc34)n2)c[nH]1 +CCn1ccc2c(cc(C(=O)NCCC(C)C)n2C)c1=O +CC(=O)c1csc(NC(=O)CCn2ccccc2=O)n1 +CC(=O)c1ccccc1NC(=O)c1cc2c([nH]c1=O)CCCC2=O +CC(C)c1ncc(CN2CCCC(c3nncn3C)C2)s1 +CCNc1ccnc(C(=O)Nc2ncc(C)s2)c1 +CC(OC(=O)C1(c2cccc(F)c2)CCC1)c1ccccn1 +O=C(NCCn1nc2c(cc1=O)CCCCC2)c1ccccc1 +O=C(Cn1nc(N2CCOCC2)ccc1=O)NC1CCCCCC1 +COC(=O)c1sc2nc(C)cc(C)c2c1-n1cccc1 +CCCCN(C)C(=O)C(NC(=O)c1cccc(C)c1)C(C)C +CCN(CC)C(=O)CN(C)C(=O)N1C(C)CCCC1C +CCC(Nc1nc2c(c(=O)[nH]c(=O)n2C)n1C)C(C)C +Cc1ccc2c(c1)OCC(=O)N2CC(=O)NCc1ccccc1 +CC(Sc1cccc(F)c1)C(=O)Nc1ccc2c(c1)OCCCO2 +CCCCNC(=O)NC1CCCOc2ccc(F)cc21 +Nc1ccc(NCC2COCCO2)cc1C(F)(F)F +Cc1ccc(C(=O)N2CCN(Cc3ccc(C4CC4C)o3)CC2)s1 +CCn1cc(NC(=O)N2CCN(S(N)(=O)=O)CC2)cn1 +Cc1ccc(CNC(=O)NCC2CCOC2)c(C)c1 +CC(=O)N1CCc2cc(C(=O)Nc3c(C)cccc3C(C)C)ccc21 +O=C1CCCc2cc(NC3CCN(CC(F)(F)F)C3=O)ccc2N1 +C=CCn1c(SCc2cn3ccccc3n2)nnc1-c1ccco1 +O=C(c1n[nH]nc1Nc1ccccc1F)N1CCOCC1 +COC(=O)c1cccc(CCNC(=O)N2CCC3(CCOC3)C2)c1 +COC(=O)N1CCCC(C(=O)Nc2nc(C)c(SC)s2)C1 +Cn1nc(C(=O)Oc2ccc(-c3ccc(C#N)cc3)cc2)ccc1=O +N#CC(NC(=O)CCc1ccccc1)c1ccccc1F +Cc1ccc(Cl)cc1NC(=O)CCn1cccn1 +COc1ncccc1CNC(=O)Nc1ccc(F)cc1 +CCCOC(=O)c1ccc(NC(=O)Cc2ccc[nH]2)cc1 +O=C(CC1CC1)N1CCC2(CCOCC2COCC2CC2)CC1 +COc1cccc(C(=O)Nc2ccc(CN3CCCC3=O)cc2)c1F +CC(C)COC(=O)N1CCCC1C(=O)Nc1ccc2c(c1)OCO2 +NC(=O)CSc1cccc(NC(=O)C2CC2)c1 +CC(C)N(CCC#N)C(=O)c1c(F)cccc1Cl +Cc1cc(-c2nc3cc(N)ccc3o2)c2ccccc2n1 +CCC(OC)C(=O)Nc1cc(OC)ccc1NC(C)=O +O=C(Cn1ncc2cccn2c1=O)NC1CCCCC1 +O=C(c1ccsc1)N1CCCC1C=Cc1ccccc1 +CCOC(=O)N1CCN(CCc2ccc3c(c2)CCCN3)CC1 +Cc1nc2ccc(S(=O)(=O)N3CCc4[nH]cnc4C3)cc2s1 +COc1cccc2c1ccn2CCNC(=O)c1ccc2c(ccn2C)c1 +O=C(C1CCCOC1c1ccccc1)N1CCc2sccc2C1 +Cn1cccc(NC(=O)NCC2Cc3ccccc3O2)c1=O +CC(C)C(C)N(C)C(=O)c1cccc(N2CCCS2(=O)=O)c1 +Cc1oc2nc3c(c(=O)n(Cc4ccc(F)cc4)c(=O)n3C)n2c1C +Cn1cc(CNC(=O)c2cn(CC=Cc3ccccc3)nn2)cn1 +CC(NC(=O)c1ccoc1)C(=O)N1CCCC1c1cccs1 +CS(=O)(=O)c1ccc(S(=O)(=O)N2CCNC(=O)C2)cc1 +CC(Nc1ccc(=O)n(C)c1)c1cccc(Br)c1 +Cc1cc(CN(C)C(=O)c2ccc(S(C)(=O)=O)cc2)no1 +c1coc(C2CC2c2nc(-c3cc4ccccc4o3)no2)c1 +Cc1cc(C)cc(N(C)S(=O)(=O)c2ccc3c(c2)CC(=O)N3)c1 +COC(=O)NCCOC(=O)Cc1ccc(Cl)cc1Cl +Cc1csc(NC(=O)C(C)Oc2ccc(F)c(F)c2)n1 +CCc1c(C#N)nnn1-c1nc(-c2ccccc2)cs1 +CCCc1cc(C(=O)NCc2cc(C)oc2C(F)(F)F)n(C)n1 +Cc1ccc(-n2nnnc2SCC(=O)Nc2ccccc2)cc1C +O=C(NCC(O)C1CC1)c1csc(-c2ccsc2)n1 +Cc1cc(C(=O)Nc2nc(-c3ccccc3)cs2)c(C)o1 +CC(=O)NC(CC(C)C)C1NCCc2c(F)cc(O)cc21 +Cc1ccc(C(=O)Nc2cc(F)c(F)cc2N)cc1C +N#Cc1cc(NCCOc2ccccc2)ccc1F +CCOc1ccccc1-n1nnc(C(=O)NC)c1N +Cc1ccc(C(=O)N(C)CC2CCCCO2)c(=O)[nH]1 +CCc1ccccc1CNC(=O)c1cc(S(N)(=O)=O)c(C)o1 +CC(C)(C)C(=O)NCC(=O)N1CCCC1c1ccccc1 +CCOC(=O)c1coc(-c2ccc3c(c2)OCO3)n1 +CCN(Cc1ccccc1)C(=O)CSc1ccc(C#N)cc1 +CCCOC1CCCN(C(=O)c2ccc(OCC(F)F)nc2)CC1 +CCc1nc(CC(=O)NC(C)c2ccc3c(c2)OCCO3)cs1 +CC1c2ccsc2CCN1c1ccc(N)cc1F +COc1ccc(CC(C#N)C(=O)N2CCCC2)cc1OC +O=C(COc1ccccc1)Nc1ccc(CN2CCOCC2)cc1 +CCCS(=O)(=O)NC(C#N)c1ccc(OC)cc1 +COCc1nc(NCCc2cc(=O)[nH]c(C)n2)c2cnn(C)c2n1 +O=C(c1ccccc1)c1ccc(N2CCOCC2)s1 +COC(=O)CC1(C(=O)OC)Nc2ccc(Cl)cc2C(=O)O1 +Cc1ccc(-c2nc(C(=O)NCc3ccc(F)cc3)cs2)n1C +CC1CCN(C(=O)c2cc(Br)cn2C(C)C)CC1 +COc1cc2c(cc1CNC(=O)CCc1c(C)nn(C)c1C)CCC2 +COc1ccccc1CNC(=O)c1ccc(-n2cncn2)cc1 +CCc1nc(CCNC(=O)c2cc(=O)c3ccccc3o2)cs1 +COc1ccc2cc(C(=O)NCC#Cc3ccc(C(C)=O)cc3)[nH]c2c1 +O=C(Cn1nnc2ccccc2c1=O)c1ccc2ccccc2c1 +N#Cc1ccccc1NC(=O)CCCN1CCCCCC1=O +Cc1csc(NC(=O)COc2ccc(C)c(C)c2)n1 +O=C(Nc1ccc(OC(=O)c2ccncc2)cc1)c1ccccc1 +CC(C)c1cc(CO)nn1-c1ccc(Br)cc1 +Cc1n[nH]c(C)c1NC(=O)C1COc2ccc(F)cc2C1 +CCc1ncc(CN(C)C(C)c2ccc(OC)cc2)cn1 +Cc1nnc(C)n1-n1ccc2c(nnc3ccnn32)c1=O +CC(C)C1CNc2ccccc2N1Cc1cccc(N)c1 +CCC1CCCN(C(=O)c2ccc(-c3nc(C)no3)cc2)C1 +Cc1cc(CCc2ccc(Cl)c(N)c2)[nH]c(=O)n1 +Cn1nc(C2CN(c3ccccc3)C2)c2nccnc21 +O=C(CSc1nc2ccc(F)cc2[nH]1)Nc1ccccc1 +OCc1ccc(COc2ccc(F)cc2Cl)o1 +CC(C)C1C(=O)NCCN1C(=O)CNC(=O)c1ccc(C#N)cc1 +CC1CCCCN1C(=O)CNC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1noc(C)c1C(=O)N1CCCc2ccccc21 +Cc1cc(NC(=O)C(C)OC(=O)c2c[nH]c3ccccc23)no1 +C=CCNC(=O)COc1ccc(CO)cc1Br +CN(C(=O)c1ccc(O)cc1)c1cccc(C#N)c1 +Cc1n[nH]cc1CNCC(O)c1cccc(Cl)c1 +Cc1cc(C)c(NC(=O)c2ccc(C)nc2N)c(C)c1 +CN(Cc1[nH]nc2c1CCC2)C(=O)Cn1c(=O)oc2ccccc21 +CCCS(=O)(=O)c1ccccc1C(=O)NC1CC1 +CCN(CC(C)C)C(=O)c1cc(Br)ccc1F +Cc1sc(-c2ccco2)nc1C(=O)NCCN1CCOCC1 +O=C(NCc1nc(-c2ccccn2)no1)OCc1ccccc1 +COc1ccc(S(=O)(=O)Nc2ccc(CC(N)=O)cc2)cc1 +CC(O)(CNC(=O)COc1ccccc1)c1cccs1 +N#Cc1cccc(CNc2ncc(C(N)=O)cc2Cl)c1 +Cc1ccc(C(=O)NCC(=O)NCCc2ccccc2)cc1C +CC(c1nc2ccccc2s1)N(C)C(=O)C1CCCO1 +Cc1csc(-c2cccc(NC(=O)C3CC=CC3)c2)n1 +Cc1ccccc1CSc1nnnn1C1CCOCC1 +Cc1noc(CSc2nc3ccccc3c(=O)n2C2CC2)n1 +Cn1cccc1C(=O)Nc1ccc(Cl)cc1Cl +CCC(C)C(=O)CSc1nc(-c2cccs2)n[nH]1 +COc1ccc(CNc2ccc(Br)cn2)cc1O +Cc1ccc(C)c(S(=O)(=O)N2CCCC2c2cc(C)no2)c1 +Cc1ccc(CN(C)Cc2nc(C)cs2)c(Br)c1 +COc1cccc(CC(=O)Nc2nnc(-c3ccn(C)n3)o2)c1 +O=S(=O)(CCc1ccccc1)NCCc1ccsc1 +O=S(=O)(NCc1ccccc1Cl)c1ccccc1F +Cc1ccc(=O)n(C(C)C(=O)NCCn2ncccc2=O)n1 +CC1(C)CN(C(=O)Nc2ccc(Oc3cccnc3)nc2)CCO1 +COC(=O)c1cc(F)cc(OC)c1NC(=O)c1ccc(F)cc1 +O=C(Nc1cnc(-c2ccccc2)nc1)c1cc(F)cc(F)c1 +COc1ccc2c(c1)N(C(=O)c1cccc(-n3cccn3)c1)CCO2 +O=C(CCc1ccc(F)c(F)c1)NCc1ccc(-n2cncn2)cc1 +CNC(=O)Cc1ccc(NC(=O)c2ccc(=O)n(C)n2)cc1 +Cc1cc(C)n(Cc2ccc(C(=O)Nc3nncs3)o2)n1 +CCC(NC(=O)C1COc2ccccc21)C(O)c1ccccc1F +Cc1nonc1OCCNC(=O)Nc1ccccc1C(C)C +Cc1nc(C2CCCN2C(=O)c2cc(Cl)c3c(c2)OCCO3)no1 +COCC(=O)Nc1nnc(-c2cccc(N)c2)s1 +NC(=O)c1ccc(NC(=O)c2cc3n(n2)CCCO3)cc1 +C=CCN(Cc1ccc(OC)cc1)C(=O)NCc1cnc(C)s1 +Cc1ccc(N2CCN(CC(=O)N3CCC(C(N)=O)CC3)C2=O)cc1 +CC(=O)N(C)c1nc(COc2cccc(S(C)(=O)=O)c2)cs1 +CC(C#N)CC(=O)N1CCC(Cc2ccccc2)CC1 +CC1CCCC(C)N1C(=O)COn1nnc2ccccc21 +O=C(NCc1csc(=O)[nH]1)c1ccc(F)cc1O +O=C(COc1ccccc1)N1CCN(C(=O)c2ccccc2F)CC1 +CN(Cc1ccccc1C#N)C1CCCN(c2ccccc2)C1=O +CC(C)c1noc(CCNC(=O)N2CCc3cc(F)ccc3C2)n1 +COCCCNC(=O)Cc1ccc2c(c1)CCCC2 +CC(Nc1ncnc2c1Cc1ccccc1OC2)c1n[nH]c(=O)[nH]1 +COC(=O)Cn1nc(C#N)cc1-c1ccc(OC)cc1C +Cc1noc(C)c1CC(=O)Nc1c[nH]cc(Br)c1=O +CCC(=O)c1ccc(OCC(=O)Nc2cc(OC)ccn2)cc1 +O=C(Nc1ccncc1F)N(CCO)Cc1ccccc1 +CCOC(=O)c1[nH]c(-c2nc3ccccc3nc2C)c(C#N)c1N +Cc1nc(-c2cccnc2SCC(=O)NCC(C)C)no1 +COc1ccc(C(c2c(O)n[nH]c2C)C(C#N)C#N)cc1 +COCC1CN(C(=O)c2ccc(C)o2)Cc2cn(C)nc21 +COc1ncccc1C(=O)NC(C)c1ccc(-n2ccnn2)cc1 +O=C(NCCC(O)c1cccs1)c1ccc(C(F)(F)F)cc1 +CCCNC(=O)NCCNC(=O)c1ccccc1F +Cc1noc(CCC(=O)NCC(C)c2nc(-c3ccccc3)no2)n1 +Cc1cccc(C)c1NC(=O)C(C)Nc1cccc(Cn2cccn2)c1 +Cc1c(CCC(=O)NCc2csc(=O)[nH]2)cnn1C +Cc1cccc(N(C)C(=O)C(N)c2ccccc2)c1 +C=CCc1c(C)nc(SCC(=O)Nc2ccc(C)cc2)[nH]c1=O +O=C(CCc1nc(-c2ccccn2)no1)NCC1CCOC1 +Cn1cc(C2CCCN2Cc2nc3ccccc3c(=O)[nH]2)cn1 +CC(CNC(=O)CCc1ccsc1)N(C)c1ccccc1 +CC(C)n1nccc1NC(=O)c1cccc2c1OCCO2 +O=C(NC(CN1CCCCCC1=O)c1ccccc1)c1ccoc1 +CN(C(=O)c1coc(-c2ccccc2)n1)c1ccccn1 +CCN(CC)c1ccc(C(=O)Nc2ccccc2Cl)cn1 +Cc1ccccc1-n1nnnc1C(C)(C)N1CCOCC1 +COC1CCCC1OC(=O)c1ccc(Cn2nc(C)cc2C)cc1 +Cc1nccn1-c1ccc(F)cc1CNC(=O)C(C)C +O=C1CN(C(=O)Nc2cc(F)cc(F)c2)CCN1 +Cc1cccc(-c2cn(C3CCCc4ccccc43)nn2)n1 +O=C(Cn1cnnn1)Nc1cccc(C(=O)N2CCCCC2)c1 +CC1CCN(c2nccc(C(=O)N(C)Cc3ccccc3)n2)CC1 +O=C(Cc1c(F)cccc1F)N1CCN(Cc2cccnc2)CC1 +COc1cccc(CC2Oc3cc(N)ccc3N(C(C)C)C2=O)c1 +CCN(CC(=O)NC)S(=O)(=O)c1ccc(C(C)=O)cc1 +CC(NC(=O)OC(C)(C)C)C(=O)N1CCc2ccc(O)cc2C1 +O=C(CC1NC(=O)c2ccccc21)NCc1cccnc1 +COc1cccc(CNC(=O)Nc2cccn3cnnc23)c1 +O=C1CCCN1c1ccc(Cl)c(C(=O)N2CCC3CCCCC32)c1 +CC(C)CNC(=O)C(C)Nc1ccc(NC(=O)C2CC2)cc1 +Cn1cc(-c2nc(Cn3cnc4ccccc4c3=O)cs2)cn1 +NC(=O)c1csc(C(=O)Nc2ccc3c4c(cccc24)CC3)c1 +CC1(C)OCC2(CO1)CN(C(=O)c1cnn(-c3ccccc3)n1)C2 +CC(Oc1ccccc1)C(=O)NCc1ccc2c(c1)OCCO2 +CCCC(=O)NCC(=O)OC(C)c1cccc(C)c1 +O=C(NCc1ccccc1Cn1cccn1)NCC1CCOC1 +Cc1ccn2c(=NC(=O)c3cnn(C)c3C)[nH]nc2c1 +CC(C)N(C(=O)COc1ccc(F)c(Cl)c1)C(C)C +O=C1CCC(C(=O)NC2(c3ccc(Cl)cc3)CC2)N1 +O=C(NCCCc1cccc(F)c1)c1ccc(-n2ccnc2)nc1 +CCc1nc(CNC(=O)c2ccc(Oc3cccnc3)cc2)cs1 +COc1ccc(CC(C)OC(=O)Cc2c(C)nn(C)c2C)cc1 +CCn1c(=O)cc(OCC(=O)N2CCCC(C)C2)c2ccccc21 +FC(F)Oc1ccccc1CNc1cccnc1 +Cc1ccc(SCCC(=O)N(CCO)C(C)C)cc1 +Cc1cnc(NC(=O)c2cncc(Br)c2)s1 +CCC(CC)NC(=O)c1nn(C)c(=O)c2ccccc12 +CCCC(C)C(=O)N1CCN(CC(=O)Nc2nncs2)CC1 +CC(O)(c1[nH]ncc1-c1ccccc1)C(F)(F)F +COc1cccc(C(=O)NC2(c3noc(C)n3)CCCC2)c1F +CN(C)c1cccc(F)c1C(=O)NC1CCCC1 +Cn1ccc2cc(CNC(=O)OC(C)(C)C)ccc21 +Cc1nc(Cc2noc(C3CC3c3ccc(C(C)C)cc3)n2)no1 +COc1ccc(C(N)=O)c(OCc2cn3cc(Cl)ccc3n2)c1 +Cc1ccc(C)n1C1CCN(C(=O)c2ccc(C(N)=O)cc2)CC1 +COc1ccc(NC(=O)NCC(O)Cc2ccccc2)c(OC)c1 +Cc1csc(C2CCCCN2C(=O)CCCn2cncn2)n1 +CNc1ncccc1C(=O)N1CCCCC1CCO +CCN(CC)C(=O)CSc1nnc(-c2cc(C)cc(C)c2)o1 +COC(C)(C)CC(C)Nc1cccc(C(N)=O)c1C +Cc1cccc(N2CCN(C(=O)c3ccccc3F)CC2)c1 +O=C(CCC1CCCO1)NCc1ccc(Br)cc1Cl +CC(=O)Nc1ccc(C(N)C(=O)NCC(C)C)cc1 +COCCN(C(=O)C1CCCCCC1)c1ccncc1 +CC(=O)NCCC(=O)N1CCN(CC(O)C(C)(C)C)CC1 +O=C(Cc1ccc(Cl)cc1)c1c(O)cc(O)cc1O +CNC(=O)c1ccc(NC(=O)NCC(=O)NC2CCCCC2)cc1 +CC(=O)N1CCc2ccccc2C1CC(=O)Oc1ccc(C)c(C)c1 +CCN(CCO)C(=O)CCC(=O)c1ccc2c(c1)CCCC2 +CCOc1cc2c(=O)ccn(CCC(N)=O)c2cc1OCC +N#Cc1ccc(CCC(=O)Nc2nc(-c3ccc[nH]3)cs2)cc1 +COc1ccc(Cn2cccc2C2=NCCO2)cc1 +O=C(CCCNC(=O)c1cccs1)Nc1cccc2cccnc12 +COc1ccc(NC(=O)COc2ccc(F)cc2)c2cccnc12 +COc1cc(Cl)c(C(O)COc2ccc(C)cc2N)cc1OC +Cc1nnc(CNC(=O)CCc2c[nH]c3ccccc23)o1 +NC(=O)c1ccc(NS(=O)(=O)c2cccc(F)c2)cc1 +Cc1ccc(C(O)CNS(=O)(=O)Cc2cccc(Cl)c2)o1 +CCC1CCC(N(C)S(=O)(=O)c2cn[nH]c2)CC1 +CCOc1ccc(NC(=O)c2ccncc2F)c(C(F)(F)F)c1 +CCc1nn(C)c(NC(=O)Cn2cnc3cc(C)c(C)cc32)c1CC +Cc1cc(NCc2c[nH]c3cc(Cl)ccc23)no1 +CCOC(=O)c1c(NC(=O)NCc2ccccc2)sc2c1CCC2 +COc1cccc(OC)c1OCCCC(=O)n1ccnc1 +C1CCCC(OCCN2CCOCC2C2CC2)CC1 +O=C(c1cscn1)N1CCCC1c1cnccn1 +COc1ccc(F)cc1-c1cc(Cl)c(C#N)cn1 +CC1COCCN1CC(=O)N1CCN(c2ncccn2)CC1 +CCn1ncc2c1CCCC2NC(C)c1nc(C(C)(C)C)no1 +CCCc1ccc(-c2cc(CO)nn2CC(N)=O)cc1 +O=C(CCC=Cc1ccccc1)NCc1ccc(-n2ccnc2)cc1 +CC(c1ccc(Cl)cc1)c1nc(-c2cccnn2)no1 +Cc1ccc(C)c(S(=O)(=O)NCCCn2cccn2)c1 +CCOC1CC(N(C)C(=O)c2c(C)noc2C)C12CCCC2 +COc1ccnc(NC(=O)c2c[nH]nc2-c2ccc(Cl)cc2)c1 +O=C(NCCNc1ncccn1)N1CCCC1c1ccncc1 +CCCCCNC(=O)Nc1nnc(CCC)s1 +CC(NC(=O)COC(=O)Cc1c[nH]c2ccccc12)c1ccccc1 +COCCN(Cc1cccc2c1OCO2)CC(F)(F)F +N#Cc1ncn(Cc2ncc(-c3ccccc3)o2)c1C#N +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)N1CCc2ccc(F)cc21 +O=C(NCCCn1ccnc1)c1ccc(Cl)cc1Cl +COC(=O)c1ncc(Br)c2ccccc12 +O=C(NC1CC1)c1nc(-n2cnnc2)ccc1Br +Cc1nc2cc(NC(=O)c3ccc4c(c3)OCC(=O)N4)ccc2o1 +CS(=O)(=O)c1ccccc1N1CCC(Oc2ccc(F)cc2)CC1 +CC(C)(O)CNC(=O)c1ccccc1Br +COc1ccc2c(c1)CN(C(=O)c1ccc(C(N)=O)cc1)CC2 +Cc1nc(-c2nc[nH]n2)sc1C(=O)N1CCOCC1CC(C)C +COc1ncccc1CNc1ccc(-n2nc(C)cc2C)cn1 +O=C(Cc1nnc(-c2cccc(F)c2)o1)NC1CCCC1 +COc1ccccc1CC(=O)NC1CNCc2cc(C)ccc21 +CCN(CCC#N)C(=O)CNc1cccc(C)c1C(N)=O +CN(C)S(=O)(=O)NCCc1csc(-c2ccccc2)n1 +CC(C)=CC1C(C(=O)N2CCN(Cc3c(C)noc3C)CC2)C1(C)C +CCC(C)C(C)N(C(=O)c1ncn(-c2ccccc2)n1)C1CC1 +O=C(c1ccc2ccccc2n1)N1CCCC1c1cccs1 +O=C(Cc1cn2ccsc2n1)NCc1ccc2c(c1)OCCO2 +COc1ccc(F)cc1NC(=O)N(C)c1c(C)noc1C +CCC(NC(=O)Nc1ccc(F)c(NC(C)=O)c1)c1cccs1 +OCCn1ncc2c(NCc3cc[nH]n3)ncnc21 +Cc1nc(CC(=O)N2CCN(c3ccccc3Cl)CC2)cs1 +O=C(Nc1nnc(-c2cccnc2)o1)c1ccccc1Cl +CCn1nc(C)c(C(=O)N2CCCCC2CN2CCOCC2)c1C +CCOc1ccc(C(C)NC(=O)c2ccco2)cc1 +COc1cc2ccccc2cc1C(=O)Nc1nnn(C)n1 +O=C(NCCN1CCOCC1)N1CCCC1Cc1ccccc1 +CCCC(NC(=O)CSc1nnc(C)s1)c1ccccc1 +Cc1ccc(C(=O)Nc2ccc(O)cc2C)c(=O)[nH]1 +CCOc1cc2c(cc1OCC)C(c1ccccn1)NCC2 +Cc1nn(C)c2ncc(CSc3nc4ccccc4n3C)cc12 +Cc1ccc(S(=O)(=O)N(C)C(=O)c2csc(C)n2)cc1 +O=C(OCc1cccc2c1OCCO2)c1cnn2cccnc12 +COC(=O)c1coc(CN(C(=O)CC(C)C)C2CCCCC2)n1 +Cc1nc(-c2cccc(NC(=O)c3c(C)nn4cccnc34)c2)n[nH]1 +COc1ccccc1C(C)N(C)C(=O)c1ccc(NC(N)=O)cc1 +CC(=O)NC1CCCN(C(=O)CCC(=O)c2ccc(F)cc2F)C1 +Cn1ncc(C(=O)NCc2ccccc2Cl)c1-n1cccc1 +Cc1ccc(NC(=O)c2cc(C)oc2C)c(Cl)c1 +CC1CC(=O)c2c(OCC(=O)Nc3cccc(F)c3)ccc(F)c21 +CCNC(=O)Nc1ccc(OC)c(OCC(F)(F)F)c1 +CC(C)N(Cc1ccccc1)C(=O)NCc1ccncc1 +CNC(=O)c1ccc(CNC(=O)c2ccc3c(c2)nc(C)n3C)cc1 +COc1cccc(Oc2ncccc2CNC(=O)C2CC=CCC2)c1 +CC(C)CCCC(C)NC(=O)c1ccc2c(c1)OCC(=O)N2 +COc1ccc(C2(C(=O)NCc3ccco3)CCOCC2)cc1 +CC(=O)Nc1ccc(F)c(NC(=O)NCC2CCCC(C)C2)c1 +NC(=O)c1ccc(NC(=O)COC(=O)C2CC3C=CC2C3)cc1 +Cc1cccc(-n2nc(-n3cnc4ccccc43)cc2N)c1 +COc1ccc(OC)c(CSc2nnnn2C2CCCC2)c1 +CC(C)(C)C(C#N)NC(=O)COc1ccc2c(c1)CCC(=O)N2 +CCCn1c(O)nnc1SCc1cc(F)ccc1OC +CCOc1ccc(-c2nc(COc3ccccc3)n[nH]2)cc1OC +Nc1nc(-c2ccccc2)ncc1C(=O)Nc1ncccn1 +CC(NCc1scnc1-c1ccccc1)C(=O)Nc1nccs1 +Cn1c(CO)nnc1SCC1CCCCCC1 +Cc1ccc2c(CNC(=O)C3CC3)cc(=O)oc2c1C +Cc1cc(N(C)C)nc(CNC(=O)C2CCCCC2)n1 +Cc1ncc(CNC(=O)N2CCCC2c2ccccc2C)s1 +CCOC(=O)c1[nH]c2ccc(OC)cc2c1NC(=O)c1ccccc1 +c1ccc2c(-c3nc(-c4ccc5c(c4)OCO5)no3)n[nH]c2c1 +CCOc1cc(CO)cc2c1OC(C)(C)C(=O)N2CCO +Cc1cnn(CCC(=O)NCc2cnc(C)s2)c1 +O=C(NC1CCc2ccccc21)c1ccc2[nH]cnc2c1 +CC(=O)c1c(C)[nH]c(C(=O)CN2CCCC2c2cccs2)c1C +CNC(=O)Cc1ccc(NC(=O)C2(c3ccc(F)cc3)CC2)cc1 +O=C(c1ccc(=O)[nH]c1)N1CCCCC1c1cccc(F)c1 +Cc1ccc2c(CC(=O)Nc3nnc(CC(C)C)s3)coc2c1 +CCC1CN(C(=O)NCc2csc(C)n2)CCO1 +CC(Oc1cc(Cl)cc(Cl)c1)C(=O)Nc1nccn(C)c1=O +CS(=O)(=O)c1ccc(-c2ccc(Br)cc2)cc1 +Nc1ccc2c(c1)N(C(=O)CCc1ccccc1Cl)CCC2 +CC(C)C(CO)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +CC(Sc1nnnn1C(C)(C)C)C(=O)Nc1ccc(Cl)cn1 +CS(=O)(=O)N(CC(=O)NCC1CC1)c1cccc(Cl)c1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)c1cn(C)c2ccccc12 +CC(=O)N1Cc2ccccc2CC1C(=O)NCc1nncn1C +COc1ccc(CNC(C(N)=O)c2ccccc2)cc1 +O=C(c1cccc(Cn2cccn2)c1)N1CCCC1c1cccnc1 +Cc1ccc(S(=O)(=O)NC(CO)c2ccccc2)cc1N(C)C +O=C(Nc1nnc(Cc2ccc3c(c2)OCO3)o1)c1ccco1 +CCc1nnc(SCC(=O)Nc2ccc(Cl)cc2)n1CC +CC1CCCCN1S(=O)(=O)NCCc1ccccc1 +Cc1cccc2c(=O)n(CC(=O)N(c3ccccc3)C(C)C)cnc12 +CC(C)c1n[nH]c(C2CCCN2S(=O)(=O)c2cccs2)n1 +COc1ccc(-c2cnc(Cn3cnc4ccccc4c3=O)o2)cc1 +COc1ccccc1C(NC(=O)C1CCN(C(C)=O)C1)C(C)(C)C +COc1cc(OC)c(C(=O)NC(C)c2ccc(F)cc2)cc1OC +Cc1ccc(-c2cc(C(=O)N3CCC(C)CC3)ccn2)s1 +COc1ccc(S(N)(=O)=O)cc1C(=O)N1CCc2ccccc21 +CC(=O)Nc1nc(C(=O)N(C)Cc2ccc(C)o2)cs1 +CC(C)COc1ccc(CNC(=O)C2CCC(=O)NC2)cc1 +C=CCOC1CCC2C1OCCN2S(=O)(=O)c1ccccc1 +O=C(NCCc1nc(-c2ccc(F)cc2)no1)c1ccc(F)cc1 +N#CCOc1cccc(CC(=O)NCc2ccc3c(c2)OCO3)c1 +C=CCNS(=O)(=O)c1cc(C)c(OCCC)cc1C +Cc1cc(NC(=O)c2c(C)oc3ncn(CC(C)C)c(=O)c23)no1 +COc1ccc(F)c(NC(=O)CCCC(=O)NC(C)C)c1 +COc1cc(NC(=O)Nc2ccccc2C)cc(OC)c1OC +CC(Oc1ccccc1)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CCOc1ccc2[nH]c(=O)c(CN3CC(C)OC(C)C3)cc2c1 +CCCN(Cc1ccsc1)C(=O)c1ccccc1OC +O=C(CO)N1CCN(C(=O)c2ccc3ccccc3n2)CC1 +CCC(C)Oc1ccc(NC(=O)c2n[nH]c3c2CCC3)cc1 +Cc1cc(C)nc(SCC(=O)Nc2ccccn2)n1 +Cc1csc(NC(=O)NCCNC(=O)c2cccnc2)n1 +CC(C)(C)C(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +CCS(=O)(=O)c1ccc(C)cc1CCC(=O)OC +O=C(NC1CC1)C1CCCN1C(=O)NC1CCCCC1n1cccn1 +COC(=O)c1cccc(NC(=O)c2cccnc2N2CCCCC2)c1 +O=C(NCC1CCCC1)N1CCCN(c2nccs2)CC1 +CC(C)(C)c1noc(CCC(=O)NC2CCSc3ccccc32)n1 +Cc1cc(NC(=O)NCCCc2ccccc2)ccc1C(=O)N(C)C +COCc1cc(C(=O)NC(C)c2cccc(N3CCCC3)c2)no1 +Cc1ccccc1CC(=O)N1CC2COCC2(CN2CCOCC2)C1 +Cc1nc2nc(C)c3c(=O)n(C4CCCCC4C)ccc3n2n1 +O=C(Nc1ccccc1-n1cncn1)c1cc(Cl)ccn1 +COc1ccc2c(=O)cc(C(=O)NCCC(C)C)oc2c1 +CC(=O)NC(C(=O)N(C)CCC(F)(F)F)C(C)C +CCc1cccc(OCCN2CCN(S(N)(=O)=O)CC2)c1 +N#Cc1cc(C#N)c(SCc2ccccc2Br)nc1N +Cc1cc(C)c(NC(=O)CNC(=O)CNC(=O)C2CC2)c(C)c1 +CC(C)(C)CC(=O)N(Cc1ccccc1)c1ccccn1 +CCC(C)n1nccc1NC(=O)Cc1ccccc1Cl +Cc1cc(C)n(-c2cccc(NC(=O)c3ccc4cc[nH]c4c3)c2)n1 +CC(C)Oc1ncc(C(=O)N2CCNC(=O)C2)cc1Cl +CCOc1ccc(F)c(C(=O)Nn2cnc3ccccc3c2=O)c1F +CC(C)c1nc2ccc(NC(=O)N3CCCC3)cc2s1 +Cc1ccc(CS(=O)(=O)NC(C#N)C(C)C)cc1 +O=C(CNC(=O)c1ccoc1)NCCc1nc2c(s1)CCCC2 +CCCCN(C)C(=O)Cn1c(CO)nc2cc(C)c(C)cc21 +Fc1ccccc1NCc1nnc2n1CCCCC2 +CCOCCOCc1cccc(NC(=O)N2CCOCC2)c1 +NC(=O)C1CCCCC1NC(=O)CCSc1ccccn1 +O=C(c1ccccc1F)N1CCC2OCCC2(COCC2CC2)C1 +CC(=O)N1CCN(C(=O)CCn2cnc3cc(F)c(F)cc32)CC1 +N#Cc1ccc(NC(=O)COC(=O)c2ccc(OC(F)F)cc2)cc1 +CCOc1ccc(C(=O)NC2CCCCNC2=O)cc1 +COc1ccc(C(=O)N(C)Cc2ccco2)cc1Br +Cc1cc(C)n2nc(CC(=O)N3CCCC3c3ccsc3)nc2n1 +CC(C)CCN(C(=O)CNC(=O)NC1CC1)C1CC1 +COC(=O)C(C)NC(=O)c1ccc2c(c1)OCCCO2 +CC1(C(=O)NCCNc2ccc3ccccc3n2)CC1(Cl)Cl +CC(=O)Nc1ccc(S(=O)(=O)n2cncn2)cc1 +NC(=O)C1CC(=O)N(c2cccc(Br)c2)C1 +COC(=O)CCc1nc2cc(Br)ccc2[nH]1 +COC(=O)c1ccc(C)c(NCc2ccncc2)c1 +CC(C)(C)CC(=O)N1CCC(c2nnc(C3CC3)s2)CC1 +COc1ccc(N)c2c(C(=O)Nc3cccc(C)c3)nccc12 +Cn1cc(NC(=O)c2cn(Cc3ccccc3)nn2)cn1 +CCN(CC(=O)NC(C)C)C(=O)Nc1ccc(C#N)cc1 +Cc1nnc(NC(=O)c2[nH]c3c(c2C)C(=O)CCC3)s1 +Cc1cccc(C(=O)NCC(=O)NCc2ccc(-n3cncn3)cc2)c1 +Cc1cccc(N2CCN(C(=O)CCc3c(C)n[nH]c3C)CC2)c1 +Cc1cc(NC(=O)c2cnn(C)c2-n2cccc2)n(C)n1 +CNS(=O)(=O)c1ccc(C(=O)NC(C2CC2)C2CC2)o1 +Cc1cccnc1NC(=O)C1(c2cc(-c3ccco3)on2)CC1 +CN(C)c1cccc(C(=O)NCC#Cc2ccc(C(N)=O)cc2)c1 +CCCCn1c(=O)c2c(nc3n(CCOC)c(C)c(C)n23)n(C)c1=O +CCOC(=O)N1CCN(C(=O)c2ccc3ccccc3c2)CC1 +CC(c1ccco1)N(C)C(=O)c1ccc(CNS(C)(=O)=O)o1 +Cn1c(=O)n(C)c2cc(C(=O)Cn3c(C#N)nc4ccccc43)ccc21 +O=C(NCCC1=CCCCC1)c1ccc(=O)n(-c2ccccc2)n1 +CC(C)N(Cc1ccccc1)C(=O)Cn1nnc(-c2ccccc2)n1 +COCCOC1CCN(C(=O)NCc2c(C)cc(C)cc2C)CC1 +O=C(C1CCOCC1)N1CCc2ncnc(C3CC3)c2CC1 +Cn1cc(-c2nn3c(Cc4ccccc4Cl)nnc3s2)cn1 +CC(Oc1ccc(Cl)cc1)C(=O)N1C(C)COCC1C +CN(Cc1ccc(F)cc1F)C(CCO)c1ccccc1 +CN(Cc1ccco1)C(=O)CN1CCCc2cccc(F)c21 +Cn1cnnc1SCC(O)COc1ccccc1 +CCc1nc(CS(=O)(=O)c2ccccc2OC)no1 +CCNC(=O)c1ccc(CNC(=O)CCC(C)C)cc1 +CCCCCNC(=O)c1cc(C)ccc1N1CCCC1=O +CCC(C)N(Cc1ccccc1)C(=O)CSc1nc(C)n[nH]1 +CN(C)C(=O)Nc1cccc(-c2ccc(N(C)C)cc2)c1 +CC(C)n1ccc2cc(C(=O)Nc3nc(C4CC4)n[nH]3)ccc21 +CC(C)NC(=O)CN(C)c1ccccc1C(C)O +Cc1ccc(NC(=O)c2ccccc2)cc1NCc1nnc(C2CC2)o1 +Nc1ccc(Cl)c(C(=O)N2CC3CCC2C3)c1 +COc1ccc(NC(=O)NCc2ccccn2)cc1F +CCc1onc(C)c1NC(=O)C(C)(C)c1cccc(C#N)c1 +CC(NC(=O)NCCc1cccs1)c1ccncc1 +C=CCCCN(C)C(=O)CCc1c(C)nc2c(C#N)cnn2c1C +CCC(Sc1nnc(-c2c[nH]c3ccccc23)n1C)C(=O)OC +O=C(CN1CCCc2cccc(F)c21)N1CCC2(CC1)OCCO2 +CCCn1ccnc1SCc1ccc(C#N)cc1 +CC(=O)N1CCc2ccc(NC(=O)c3cc(=O)c4ccccc4o3)cc21 +O=C(Nc1ccc(Cl)cc1)c1cccn(Cc2ccccc2)c1=O +COC1=NS(=O)(=O)c2cc(OC)ccc2N1C +COC(=O)c1n[nH]c2cc(Br)cc(F)c12 +CC(=O)N(C)c1cccc(NC(=O)NC2C3CCC(C3)C2CO)c1 +CC(=O)NCCOc1ccc(-c2nc(C)nn2-c2ccccn2)cc1 +Cc1cc(C)nc(N2CCN(c3nc(N)nc4[nH]cnc34)CC2)n1 +COCc1oc(C)cc1-c1nnc(NC(C)C)s1 +Cn1ncc(N2CCC(C(=O)N3CCCC3)CC2)c(Cl)c1=O +CC(NC(=O)Cc1ccccc1O)c1ccc2c(c1)OCO2 +CNC(=O)CN(C)C(=O)CNC(=O)c1cccc(Br)c1 +N#CC1(C(=O)Nc2ncc(C(N)=O)s2)CCCCC1 +Cc1cc(-c2cnc(NCc3ccccn3)nc2C2CCCO2)on1 +Nc1oc(-c2ccco2)cc1C(=O)c1ccc(F)c(F)c1 +Cc1cc(=O)n(CC(=O)Nc2ccc(C)c(Cl)c2)cn1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NC1C2CCC(C2)C1CO +CCC(C)NC(=O)Cc1csc(COc2ccccc2)n1 +CCC(=O)c1ccccc1OCc1cnn(CC)c1 +O=C(c1ccc(F)cc1F)N(Cc1ccsc1)Cc1ccco1 +CCCN(C(C)C)S(=O)(=O)c1cc(N)ccc1C +CC(OC(=O)c1c(F)cccc1F)C(=O)Nc1ccccc1 +COc1ccc(CCNc2nc(-c3cccnc3)cs2)cc1OC +CSc1ccc(NC(=O)N2CCNC(=O)C2)cc1 +Cc1ccc(CN2C(=O)CCC2C(=O)OCc2cnn(C)c2)cc1 +CCc1ccc(C(O)CNC(=O)c2ccc(F)c(F)c2)cc1 +CCOC(=O)c1cc(C)sc1NC(=O)CSc1nccn1C +Cc1ccc(S(=O)(=O)NC2CCCCC2O)c(N)c1 +Cc1cc(NC(=O)CCN(C)Cc2nc3ccccc3c(=O)[nH]2)no1 +CCc1cc(C(=O)NC(C)c2ccncc2)sc1C +O=C(C1CC1)N1CCC2(CCCN(c3ncccn3)C2)CC1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)NC(C)c3nc[nH]n3)ccc21 +COc1ccc(C2CCCN2C(=O)Cn2cnc(C#N)n2)cc1 +O=C(CCCc1ccccn1)N1CCSc2ncccc21 +COC(=O)c1ccc(OC(C)C(=O)NCC(F)(F)F)cc1 +CCC(NC(=O)C(C)Sc1ccccn1)c1c(C)nn(C)c1C +C#CCNC(=O)C(C)Sc1nnc(N)n1C(C)C +O=C(CNCC(F)(F)F)N1CCCC1c1ccc2c(c1)OCCO2 +CCOC(=O)CCCNC(=O)N1CCC(c2ccc(O)cc2)CC1 +NC(=O)c1cccc(NCc2ccc3cc[nH]c3c2)c1 +O=C(c1cccc(F)c1)N(CCc1cccs1)Cc1ccoc1 +Cc1cc(C)c(NC(=O)CCc2cccnc2)c(C)c1 +CCC(C)C(C)NC(=O)CCc1c(C)nc2ncnn2c1C +CC(=O)N1CCc2cc(NS(C)(=O)=O)ccc21 +O=C(CCCNC(=O)c1ccco1)Oc1cccc(F)c1 +CC(=O)N1CCC(NC(=O)c2sccc2C)C1 +CCc1nc(CN(C)C(=O)C(C)OCc2ccccc2)cs1 +CC(CO)NC(=O)CCc1ncc(-c2ccccc2Cl)o1 +COc1ccc(CCN2Cc3ccccc3CC2C(N)=O)cc1 +Cc1ccsc1CN1CCN(C(=O)CCC(C)C)CC1 +COC(=O)c1occc1CN1CCOCC1C1CC1 +COc1ccc(C(C)(C)C)cc1-c1cnnc(N)n1 +C#CCNC(=O)CSc1nnc2nc(C)cc(C)n12 +CCN1CC(=O)Nc2cc(S(=O)(=O)N3CCOCC3)ccc21 +Cn1ncc2c(=O)n(CC(=O)N3CCOC4CCCCC43)cnc21 +N#CCc1ccc(OCc2cccc(NC(=O)Nc3cn[nH]c3)c2)cc1 +CS(=O)(=O)NCCC(=O)N1CCCC(c2ccccc2)CC1 +Cc1ccc(C(=O)CCC(=O)Nc2cccc(O)c2)cc1 +Cn1nnc2c(SCc3cccnc3)ncnc21 +CC(=O)c1ccccc1OCCN1C(=O)c2ccccc2S1(=O)=O +CCCN1C(=O)C2CCC1CN(C(=O)c1ccc(Cl)c(F)c1)C2 +COCCNS(=O)(=O)c1ccc(CNC(C)=O)cc1 +CCc1ccc(CNc2ccc3oc(=O)[nH]c3c2)s1 +CCC(C)C(=O)Cn1cnc2c(cnn2-c2ccccc2C)c1=O +Nc1cc(-c2cccs2)nn(CC(=O)N2CCCCC2)c1=O +Cn1cc(NC(=O)Nc2nnc(CC3CCCC3)s2)cn1 +CCNC(=O)NCCc1ccc(F)c(Br)c1 +CC(C)(C)OC(=O)NC1(CNC(=O)c2cscn2)CCCCC1 +CN(Cc1ccccn1)C(=O)c1n[nH]c2c1CN(C1CCOC1)CC2 +CCC(C)C(=O)Nc1cccc(CNC(=O)N2CCCC(CO)C2)c1 +CCCC1CN(Cc2c(CC)nn(C)c2OC)CCO1 +COc1cccc(C(=O)N(Cc2ccc(F)cc2)CC2CCCO2)c1 +CNC(=O)NCC(=O)Nc1cccc(N2CCCCCC2)c1 +Cc1ccnc2c1c1c(n2-c2ccccc2)C(C)NCC1 +CN(CCNC(=O)Nc1ccn(Cc2ccccc2)n1)c1ccccc1 +N#CCCNC(=O)CNc1ccc2c(c1)Cc1ccccc1-2 +CN(Cc1ccccc1N1CCCC1)C(=O)c1ccc2c(c1)OCO2 +CCn1cc(NS(=O)(=O)c2ccc(C(=O)OC)cc2)cn1 +Cc1cc(C)nc(N2CCC(c3nc(C)no3)CC2)n1 +CC1CC1C(=O)Nc1nc(-c2ccccc2)cs1 +CN(CCc1nccs1)Cc1cc(O)ccc1Br +CCOc1cc2c(cc1OCC)C(C1CC(=O)C1)NCC2 +Cc1ccccc1Nc1nc2[nH]ncc2c(=O)n1N +Cn1nnc2cc(C(=O)NCC3CN4CCCCC4CO3)ccc21 +O=C(NCc1ccc(Br)c(F)c1)Nc1cn[nH]c1 +CCN(C(=O)c1ccc(C(=O)N(C)C)cc1)c1ccccc1C +COc1ccnc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)c1 +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1cccs1 +Cc1cccc(NC(=O)c2sc3ncccc3c2N)c1C +COc1ccc(Cl)cc1C(=O)Nc1cn[nH]c1 +O=C(CCc1cc(Br)cs1)NCCC1CCCO1 +N#CC(CC(=O)Nc1cccc(Cl)c1)c1cccnc1 +Cn1c(N)nnc1SCC(=O)Nc1ccc(Cl)cc1 +CCN(CC1CCOC1)C(=O)CNC(=O)c1ccccc1Cl +NC(=O)c1csc(C(=O)NC(c2ccc(F)cc2)C2CCCO2)c1 +Cn1cnnc1SCc1nc(N)c2c3c(sc2n1)CCCC3 +CSc1ncc(C(=O)N2CCC(Cc3ccccc3F)CC2)cn1 +Cn1cc(CN2CCN(C(=O)c3ccoc3)CC2)ccc1=O +N#Cc1cccc(C(=O)N2CCC(c3nnc(C4CC4)o3)CC2)c1 +CC(C)CNC(=O)c1cc(N2C(=O)CCS2(=O)=O)ccc1Cl +Cc1c(-c2nc(-c3ccsc3)no2)sc2ncn(C)c(=O)c12 +COCC(=O)N1CCN(C(=O)COc2ccccc2)CC1 +CC(=O)Nc1ccc(Cl)c(C(=O)NCc2cn3ccccc3n2)c1 +CNC(=O)NCC(=O)N1CCCC1c1ccc(C)c(C)c1 +COc1ccc(OC)c(CN(C)C(=O)c2nccnc2N)c1 +COc1ccc(C)c(NC(=O)NCc2cnn(C)c2C)c1 +COCCN(CC(C)C)C(=O)c1cccc(OC)c1F +COc1nccnc1-c1cccc(C(=O)c2nccn2C)c1 +CC(C)NC(=O)c1scc(S(C)(=O)=O)c1Cl +CCC(C)NC(=O)c1oc2ccccc2c1COC +CCC(CCNC(=O)c1cn2ccc(C)cc2n1)N1CCCC1=O +O=C1NCCCn2cc(S(=O)(=O)N3CCCC3)cc21 +Cc1ccc2ncc(C(=O)NCCc3ccc(F)cc3)n2c1 +Cc1nc(-c2ccc(NC(=O)c3ccccc3)c(C)c2)no1 +CC(C)c1c(C2CCN(C(=O)c3ccoc3)CC2)noc1N +CC(C)CC(C#N)NS(=O)(=O)c1ccc(Cl)cc1 +Cc1noc(C)c1CNC(=O)NCCc1cccnc1 +CC(NC(=O)Cc1csc(-c2ccccn2)n1)c1ccncc1 +CCOC(=O)c1oc2ccccc2c1COc1ccccn1 +CC(O)CNC(=O)c1cccc(OCc2cn3ccccc3n2)c1 +CC(C)OCCC(=O)Nc1nnc(C(C)(C)C)s1 +COc1ccccc1OCc1ccc(C(=O)N2CCNC(=O)C2)o1 +COc1ccc(CC(=O)Nc2ccc(S(C)(=O)=O)cc2)cc1C +CN(C)C(=O)Cc1ccc(NCc2csnn2)cc1 +O=C(COc1ccc2c(c1)CCC2)Nc1ccncc1 +COc1ccc(-c2cc(CO)c(C3CC3)o2)cc1Cl +COC(=O)C1=Nc2nnnn2C(c2cccc(O)c2)C1C(C)=O +C#CCNC(=O)c1cc(S(=O)(=O)NC(C)C)ccc1Cl +Cc1cc(CCNC(=O)Cn2cnc3ccccc32)on1 +CCOC(=O)c1nnsc1NC(=O)c1cccc(N(C)C)c1 +CNC(=O)c1cn(CCOC)c2cccc(N)c2c1=O +CCOCCCNS(=O)(=O)c1ccccc1N +Cc1cc2c(c(C)c1Br)C(=O)C(=O)N2 +CC(C)(C)c1ccc(CSc2nnc(CN3CCCC3=O)o2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)NC(CC)c1nc(C)cs1 +CCOCCNC(=O)c1cc(S(C)(=O)=O)c(Cl)cc1Cl +Cc1nnsc1-c1nnc2sc(-c3cc(C(C)C)n(C)n3)nn12 +CCOc1cc2[nH]c(=O)[nH]c(=O)c2cc1OCC +NC(=O)c1ccccc1NC(=O)Cn1c(=O)cnc2ccccc21 +O=C(c1c(F)cccc1Cl)N1CCCC1Cn1cccn1 +CCC(C)(C)NC(=O)CS(=O)(=O)c1nncn1C(C)C +CCOc1c(Br)cc(C(=O)NC)cc1OC +COC(=O)C1CN(C(=O)OC(C)(C)C)CCC1(F)F +COc1ccc(C(=O)N2CCCN(c3ccc(F)cc3)CC2)cc1C +Cc1ccc(Cc2nc(C(=O)OCC3CNC(=O)C3)cs2)cc1 +CCOC(=O)c1nnsc1NC(=O)c1ccc(Cl)cc1Cl +Cc1ccsc1C(=O)N1CCSc2ccc(N)cc21 +Cc1cc(O)cc2occ(-c3ccccc3)c(=O)c12 +CCCS(=O)(=O)N1CCCC(CNS(C)(=O)=O)C1 +O=c1[nH]c(NC2CCN(c3ccccc3)C2)nc2ccccc12 +COc1ccc(OCCCC(=O)Nc2nccs2)cc1 +CC(C#N)CSc1ccccc1NC(=O)NCc1ncc[nH]1 +CCc1ccc(CN(C)C(=O)c2cccc(S(=O)(=O)NC)c2)cc1 +CC(C1CC1)N(C(=O)CN1CCN(c2ccc(O)cc2)CC1)C1CC1 +COCC(C)NC(=O)c1ccc(NC(C)=O)cc1 +CCOC(=O)C1CCN(C(=O)OCC)CCC1=O +CCn1cc(Nc2ncnc3c2NC(=O)CN3)cn1 +N#Cc1cnn(C(=O)CCn2ccc3cc(Cl)ccc32)c1N +Cc1occc1CN(C)C(=O)NCc1ccccn1 +N#Cc1cccc(NC(=O)N2CCC(c3cc(N)on3)CC2)c1 +COC(=O)c1cc(NCc2sccc2C)ccc1F +CC1CN(S(=O)(=O)N2CCc3sccc3C2)CC(C)O1 +N#Cc1cccc(CS(=O)(=O)Nc2ccc(OC(F)F)cc2)c1 +CCOC(=O)CCC(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +CSc1nc2cc(-c3ccc(C)cc3)sc2c(=O)n1N +Cc1ccc(-c2nc(C(=O)Nc3nc4ccccc4[nH]3)cs2)o1 +CCOC(=O)c1ncccc1NC(=O)C1C2CCCCC21 +Cc1ccc(N(CC(=O)N2CCCC(C)C2)S(C)(=O)=O)c(C)c1 +CCc1nnc(NC2CC3CCC2O3)c(C#N)c1CC +COc1ccc(Cl)cc1NC(=O)c1ccc2nccnc2c1 +COc1ccc(NC(C)=O)cc1NCCOc1ccccc1 +CCc1cc(N2CCN(C3CCCC3)C(=O)C2)n2nccc2n1 +CCn1cnnc1C1CCN(C(=O)c2ccc3c(c2)CCO3)CC1 +Cc1cccc(N2CC(C(=O)NCc3ccccc3)CC2=O)c1 +CCOC(CC)C(=O)Nc1ccc(NC(C)=O)c(Cl)c1 +O=C(Nc1nnc(-c2ccccc2Cl)s1)C1CC1 +Cc1ccc2nc(COC3CN(CC4CC4)CC3F)[nH]c2c1 +CN1c2ccccc2C2CN(C(=O)C3CC3)CCC21 +Cc1cc(C2CCCN2C(=O)c2cc(-c3ccc(C)s3)n[nH]2)on1 +N#CCCCS(=O)(=O)N1CCc2c1cccc2C(F)(F)F +CCOC(C)C(=O)N1CCOC(c2cccc(OC(F)F)c2)C1 +CN(CC(C)(C)O)C(=O)NCC1(c2ccccc2Cl)CC1 +c1coc(-c2cn3c4ccccc4n(CCN4CCOCC4)c3n2)c1 +CC(Oc1ccc(C#N)cc1)C(=O)N(C)Cc1ccc2c(c1)OCO2 +Cc1cc(C)n(-c2ccc(SCC(=O)N3CCCCCC3)nn2)n1 +CCn1nnc2cc(C(=O)Nc3nccs3)ccc21 +CC(C(=O)NCc1ccccc1OC(F)(F)F)n1cncn1 +NC(=O)C1CCc2sc(C(=O)N3CCOCC3)cc2C1 +CCc1nc2ccccc2n1CC(=O)Nc1nnc(C)s1 +COc1ccccc1C(=O)N1CCN(Cc2ccccc2C)CC1 +CN(Cc1ccc(F)cc1)C(=O)Cn1cc(-c2ccccc2)cn1 +O=C(CCCC(O)c1ccc(F)c(F)c1)NC1CCCC1 +COCCc1nc2ccc(C(=O)NCc3n[nH]c4c3CCC4)cc2o1 +O=S(=O)(NC1CC2CCC1O2)c1c(F)cccc1Cl +CN1C(=O)C(C)(C)c2cc(C(=O)Cn3cc(N)cn3)ccc21 +CN(CC1CC1)C(=O)Cn1ccnc1-c1cncc(Br)c1 +Cc1nc(C)c(C(=O)NCc2ccc3c(c2)OCO3)s1 +C=CCn1c(SCC(=O)NC2CCCC2)nnc1-c1cccs1 +CCCCN(CC)C(=O)c1cc(=O)[nH]c2ccccc12 +CCCCOC(=O)Cn1cnc2sc(CC)cc2c1=O +Cc1sc2ncnc(N3CCCC(n4cncn4)C3)c2c1C +O=C(CCNC(=O)c1cc2sccc2[nH]1)Nc1ccc(F)cc1 +CN1CC(C(=O)N(Cc2ccccn2)c2ccc(F)cc2)CC1=O +O=C(CSc1ncc2ccccn12)NCC1(c2ccccc2)CC1 +COC(=O)c1c(-c2cc(F)ccc2F)noc1N +Cc1nc2ccccc2nc1-c1nnc(CC(C)C)s1 +CCOc1cccc(-c2ncc(C(=O)NC(C)C)c(N)n2)c1 +CC(NS(=O)(=O)c1ccc(F)cc1Br)c1ccco1 +O=C(OCc1cccc(-n2cccn2)c1)c1scnc1C1CC1 +Cc1cc(C(=O)CSc2ccc(F)cc2)c(C)n1C1CC1 +COCCN1C(C)CN(Cc2cnc(C(C)C)s2)CC1C +Cc1nnnn1-c1cc(NC(=O)C2CC=CC2)ccc1F +Cc1ccc(NC(=O)c2cccc(Oc3cnccn3)c2)nc1 +O=c1c2ccsc2ncn1Cc1coc(-c2ccc(F)cc2)n1 +Cc1nc(Nc2ncccn2)cc(C2CN(c3ccncn3)C2)n1 +O=C(Nc1ccc(-n2cncn2)cc1)c1ccsc1 +O=C(CCS(=O)(=O)N1CCc2ccccc21)OCc1ccccc1 +Cn1nccc1CNC(=O)CNC(=O)c1ccsc1 +CCOc1ccc(C(=O)CCC(=O)NC2CCCC2)cc1 +OCCn1nc(-c2c(F)cccc2Cl)c2c1CCNC2 +Cc1c(C(=O)N2CCC3(CC2)OCCO3)cnn1-c1ccc(F)cc1 +O=C(CSc1ccc(F)cc1)NCCC(O)c1ccccc1 +Cc1nnc(SCc2cc3c(cc2Cl)OCO3)s1 +CC(c1ccc(F)cc1)N(C)C(=O)CCc1nc2ccccc2[nH]1 +Cc1noc(OCc2cc(=O)n3cccc(C)c3n2)n1 +O=C(Cn1cc(C(F)(F)F)cc(Cl)c1=O)c1ccc[nH]1 +O=C(c1cccc2c1OCO2)N1CCC(c2nnc3n2CCC3)CC1 +CCn1nnc2cc(C(=O)NCCc3ccccc3F)ccc21 +O=c1c2ccccc2nc(C=Cc2ccccc2O)n1CCCO +COC(=O)C(C)CNC(=O)Nc1ccc(-c2nc(C)cs2)cc1 +COCCCN1C(=O)C(=O)c2cc(Cl)ccc21 +CC(Nc1ccc2nnnn2n1)c1cccc2ccccc12 +O=C(NCc1ccccc1F)N1CCC(C2OCCO2)CC1 +COc1ccc(C(=O)Nc2nc(-c3ccccn3)cs2)c(OC)c1 +COc1ccccc1NC(=O)C1CCN(C(=O)Cc2ccon2)CC1 +CCc1onc(C)c1NC(=O)CCOc1cccc(C)c1C +Cc1cc(C(=O)NCc2ccccc2F)nc(N2CCCC2)n1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(Br)cn1 +CN(Cc1cccc(C(N)=O)c1)c1cn[nH]c(=O)c1Cl +Cc1csc(CN2CCC3(CCCN(C4CCOCC4)C3=O)C2)n1 +CC1CN(C(=O)C2CCC(F)(F)CC2)c2cccnc2O1 +CCOc1ccnc(NCc2nc(-c3ccccn3)no2)n1 +Cc1n[nH]c(SCCCOc2ccc3c(c2)OCO3)n1 +Cn1cnn(Cc2cc(Cl)c3c(c2)OCCO3)c1=O +N#CC(Cc1ccccc1F)C(=O)NC1CCCC1 +Cc1nc(C(C)C)sc1C(=O)N(C)Cc1noc2c1CCCC2 +COCCNS(=O)(=O)c1c(C)nn(-c2ccccc2)c1C +Cc1ccc(C)c(CCCC(=O)N2CCC(=O)CC2)c1 +O=C(NCc1cnn2ccccc12)Nc1ccc(F)cc1 +CNC(=O)c1cccc(NC(=O)NCc2ccc(OC)c(F)c2)c1C +Cc1[nH]ccc1C(=O)NC1CCCN(Cc2ccccc2)C1=O +CN1CCN(C2CCN(c3ccc(C#N)cn3)CC2)C1=O +O=C(Nc1cc(=O)[nH]c(=O)[nH]1)NS(=O)(=O)c1ccccc1Cl +O=C(NC1CCCC1)c1cccc(-n2cnnn2)c1 +CCN(C(=O)CSc1nncn1-c1cccc(Cl)c1)C1CC1 +O=C(CN1C(=O)CSc2ccccc21)Nc1cccc(O)c1 +CCS(=O)(=O)c1ccccc1C(=O)Nc1ccnc(C)c1 +Cn1c(SCc2ccc(C(=O)N3CCCC3)cc2)n[nH]c1=O +N#CC1(NC(=O)c2cc(C3CC3)nc3c2cnn3C2CCCCC2)CC1 +O=C(NCc1ncc(-c2ccccc2)[nH]1)c1cc(Cl)c[nH]1 +Cc1cc(C)nc(CN(C)C(=O)C(c2cccnc2)N2CCCC2)c1 +Cc1ccc(C)c(CSc2nnc(N)n2C2CC2)c1 +CC1COc2ccccc2N1C(=O)CCn1nc2ccccn2c1=O +Cn1cccc1C(=O)NCc1nc(-c2ccncc2)cs1 +CCCn1nc(C(=O)N2CCCCC2)c2ccccc2c1=O +CCC(C)C(=O)NCC(=O)Nc1ccc(Cl)cc1 +O=C(CNC(=O)c1ccc2c(c1)OCO2)NCC1CC1 +COC(=O)c1cccc(C(=O)Nc2ccccc2O)c1 +CC(=O)c1ccc(NC(=O)Cc2ccc(C)cc2)cc1 +CC(C)N(c1ccc(Cl)cc1)S(=O)(=O)c1cnn(C)c1 +Cc1cc(C(=O)CN2CCOCC2)c(C)n1-c1nccs1 +Cc1nn2cc(C(=O)NCc3cccs3)nc2s1 +COc1cc(OC)c(-c2cc(=O)c(C#N)c[nH]2)cc1OC +O=C(c1c[nH]nn1)N1CCN(c2ncc(Br)cn2)CC1 +N#Cc1ccccc1CN1CCNc2cc(F)ccc21 +C=CCn1c(C)nnc1Sc1ncnc2sc3c(c12)CCCC3 +COC(=O)c1ccc(CN(C)S(=O)(=O)c2ccccc2)o1 +COc1ccc(CNC(C)C(=O)NC2CCCCC2C)cc1 +Cc1nn(C(C)C)c(C)c1NC(=O)c1[nH]nc2c1CCCC2 +CCOc1cc2c(cc1OC)CC(C(C)C)c1c-2c(=O)c1=O +COc1ccc(C(=O)Nc2ccccc2C(=O)OCC#N)cc1 +O=C(Oc1ccc(Cl)cc1)c1cc(C2CC2)[nH]n1 +CCOc1nc(CN2CCN(c3ccccc3)CC2)n[nH]1 +CN(C)C(=O)CSc1nc(-c2ccccc2F)n[nH]1 +CCn1c(=O)n(CC(=O)N2CCOCC2CC(C)C)c2ccccc21 +N#Cc1c(-c2ccccc2)cc(-c2ccco2)c(C#N)c1N +O=C(Nc1cnn(CC2CC2)c1)c1c(F)c(F)c(F)c(F)c1F +CC(C)(C)C(=O)NCC(=O)Nc1ccc(NC(N)=O)cc1 +CCCCC1NCCc2ccc(Cl)c(OC)c21 +C#CCOc1ccccc1CN1CCOC2CCCCC21 +N#Cc1cc(NC(=O)c2cccnc2OCC(F)F)ccc1F +CCC(=O)Nc1ccc(O)c(C(=O)NCc2cccc(C#N)c2)c1 +Cc1ccc(NS(=O)(=O)c2ccc(-c3ccc(=O)[nH]n3)o2)cc1F +O=C(CCN1CCOC2CCCCC21)N1CCOCC1 +CCCn1ccc2sc(C)c(C(=O)NCc3ccc(C)o3)c2c1=O +COCCNC(=O)c1ccc2c(c1)n(C)c(=O)c1ccnn12 +COc1cccc(NC(=O)n2nc(C)c3ccccc32)c1 +Cc1ccc(C)n1-c1c(C(=O)NC2CCCc3ccccc32)cnn1C +Cc1ccc(Cc2cnc(NC(=O)CC#N)s2)cc1 +CCc1cn[nH]c1C1CCCN(C(=O)c2[nH]cnc2C)C1 +O=C(Nc1cccnc1)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +CC(C)CC1COCCN1CCC(=O)Nc1cccc(F)c1 +CCN(Cc1cnc2ccccn12)C(=O)c1cc(=O)c2ccccc2o1 +O=C(COc1ccc(S(=O)(=O)c2ccccc2)cc1)N1CCC1 +N#CC1(C(=O)NCC(=O)Nc2nccs2)CCCC1 +Cc1csc(C(C#N)C(=O)c2cccc(NC(=O)NC3CC3)c2)n1 +CCN(CC(C)C#N)C(=O)c1ccccc1S(=O)(=O)CC +CC1(C)Cc2occc2C(NC(=O)C2CCCCC2)C1 +O=C(NCCc1ccc(OC(F)F)cc1)c1nccn2ccnc12 +O=C(Nc1ccncc1)N1CCCC(c2nnc3n2CCCCC3)C1 +Cn1cc(C2CCCN2C(=O)c2cc3c(s2)CCOC3)cn1 +CC(C)CCn1c(CNC(=O)c2ccncc2)nc2ccccc21 +COc1ccc(C(=O)NCc2ccc(C)n2C)cc1 +Cc1c(C(=O)N2CCC3(CCCCC3)C2)cnn1-c1ccncc1 +CCn1nc(C)c(C(=O)Nc2nnc(C)s2)c1C +CC(=O)c1sc(CCNCc2ccncc2)nc1C +CN(CCCOc1ccccc1)C(=O)Nc1ccc2c(c1)COC2 +Cc1noc(C)c1CCC(=O)NC(C)c1cccc(N2CCCC2)c1 +CCC(NS(=O)(=O)c1cccc2ccccc12)C(=O)OC +CC1CCN(C(=O)c2ccccc2NC(=O)NC(C)C(C)C)CC1 +CCc1c(C)nn(Cc2nc(C3CCOC3)no2)c1C +COc1ccc(-c2n[nH]c(SCC3CCCO3)n2)cc1 +Cc1ccc(C(=O)Nc2ccc(N3CCCC3=O)cc2)c(C)c1 +CC1CN(S(=O)(=O)c2ccc(C(F)(F)F)nc2)CC1C +CCC1CN(C(=O)c2nc(C(C)C)ncc2Cl)CCO1 +O=C(C1CCN(c2ncnc3cccc(F)c23)CC1)N1CCCC1 +CCC(=O)N1CCN(c2cc(N)ccc2OC)CC1 +CC(C)C(NC(=O)c1cnn(-c2ccc(F)cc2)n1)C(N)=O +CCCC1CN(C(=O)c2cccc(Nc3ccc(C)nn3)c2)CCO1 +COc1ccccc1CC(=O)NCc1nc(-c2ccc(C)cc2)no1 +C=CCOc1cccc(NC(=O)Nc2cnn(CC3CCCO3)c2)c1 +O=C(c1cnn2ccccc12)N1CCCC(Cn2cc(CO)nn2)C1 +Cc1ccc(-c2ocnc2C(=O)NC2CCCc3ccccc32)s1 +CC(=Cc1nc(CC(=O)NC2CCCC2)no1)c1ccccc1 +c1ccc(C(NCCc2nccs2)C2CC2)cc1 +Cc1cccc(N(C)S(=O)(=O)c2c(C)noc2C)c1 +COCc1ccccc1C(=O)Nc1ccc(C(=O)NCC(C)C)cc1 +COC(=O)c1cncc(C(=O)NCc2cccc(N(C)C)c2)c1 +O=C(CCOCC1CCCO1)N1CCCC(O)C1 +O=C(CCNC(=O)c1cccs1)Nc1ccc2c(c1)OCCCO2 +CC(C)n1nccc1NC(=O)NCC(CO)Cc1cccs1 +N#Cc1ccc(F)cc1CNc1ccc(-n2cc(CO)nn2)cc1 +Cc1ccc(S(=O)(=O)Oc2ccc(CC#N)cc2)cc1F +CCn1cc(C(=O)N2CCCC2)c(=O)c2c(N)cccc21 +CCOc1cc(C2CC(=O)Nc3c2c(C)nn3C)ccc1OC +C#CCNC(=O)NCc1ccccc1OC(F)(F)F +CCOC(=O)c1cccc(NC(=O)NCCO)c1 +CNS(=O)(=O)Cc1ccc(CNC(=O)c2ccn(C)c(=O)c2)cc1 +CCOc1ccc(C(O)CNC(=O)c2ccco2)cc1 +O=C(CNC(=O)Nc1ccccc1SCC(F)(F)F)NC1CC1 +CCNC(=O)C(C)Sc1nnnn1C(C)(C)C +O=C(CCc1nc2ccccc2s1)NCc1nnc2n1CCC2 +CC(C)NC(=O)Cn1c(=O)nc(-c2ccccc2)c2ccccc21 +COc1ccc(CN2CCOC(c3cnn(C)c3)C2)c(OC)c1OC +COc1ccc2cc(CN(C)C(C)c3nccs3)c(=O)[nH]c2c1 +CCOC(CC)C(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +COc1cc(C(=O)OC(C)C(=O)c2ccccc2)cc(OC)c1O +O=C(Nc1ccc(Br)cc1F)c1ccc(O)cc1 +CCOc1ccc(C(=O)NCc2ccc(C)cc2)cc1 +CC(C)(C)NC(=O)CNCc1cccc(OC(F)(F)F)c1 +CC(C)C(C)(C#N)NC(=O)COc1nc(-c2ccccc2Cl)no1 +Cc1noc(CNC(=O)c2ccc(Cl)c(N)c2)n1 +CC(C)CC(=O)NCC(=O)c1ccc2c(c1)CCC2 +COC(=O)C1CN(CC(=O)NCc2ccccc2)c2ccccc21 +COC(C)C(=O)Nc1nnc(C2CCCCC2)s1 +COC(=O)c1cc(Cl)ccc1NC(=O)c1ccc(C)nc1C +CCCCN(C(=O)Cn1nc(C)c2ccccc2c1=O)C(C)CC +CCCNC(=O)Cn1c(=O)n(C(C)CC)c(=O)c2ccccc21 +CCN(Cc1ccncc1)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +C=CCN(CC#Cc1ccccc1)C(=O)C1COc2ccccc2O1 +COc1ccc(NC(=O)NCCc2cccs2)c(OC)c1 +Cc1cccc(C(=O)N(C)C(C#N)c2ccccc2Cl)c1 +Cc1nc2ccc(NC(=O)CN(C)C(=O)c3cccs3)cc2o1 +Cc1nnc(C2COC3CN(C(=O)Cc4ccccn4)CC32)o1 +COc1ccc(CN(CC(C)C)C(=O)c2ccoc2)cc1 +Cc1cc(CNc2ccc(F)cc2F)c(C)s1 +CCc1cc(N)cc2c(CC(=O)Nc3ccccc3)noc12 +CCOc1ccccc1OCCn1c(=O)oc2ccccc21 +O=C(COc1ccccc1Cl)NCc1ccccn1 +CCC(=O)c1ccc2c(c1)N(CC(N)=O)C(=O)C(CC)(CC)O2 +CCCCOc1ccc(-c2ncc(C#N)c(N)n2)cc1 +CNC(=O)Nc1ccccc1C(=O)N1CCCCC1 +CC(=O)Nc1cc(C(=O)N(C)Cc2ccc(C(C)C)cc2)ccc1F +COC(=O)c1ccc2cc(N3CCOCC3)ccc2n1 +CN(Cc1ccccc1F)C(=O)c1n[nH]c(=O)c2ccccc12 +COc1ccc(CNc2nccn(-c3cccc(C)c3)c2=O)cc1 +COc1cccc(CN2CCN(c3ccc4nnc(C)n4n3)CC2)c1 +CC(C)n1c(C2CCCN(Cc3ccco3)C2)nc2ccccc21 +N#Cc1cccc(CNC(=O)Nc2nnc(C(F)(F)F)s2)c1 +COc1ccc(OC)c(CSc2nc(N)cc(N)n2)c1 +N#Cc1ccc(-c2noc(-c3ccn(-c4ccc(F)cc4)n3)n2)nc1 +CC(CCCO)NC(=O)NCC(=O)N1CCc2ccccc21 +Cc1c(NCC(=O)NC(C)c2cccs2)cccc1C(N)=O +Cc1ccncc1C(=O)N1CCC(CO)C(O)C1 +CC(=O)N1CCCN(C(=O)CCc2nc(-c3ccccc3)no2)CC1 +O=C(NC(c1ccc(Cl)cc1)C(F)(F)F)c1cnns1 +Cc1ccc(-c2n[nH]c(SCc3nc(C)c(C)o3)n2)cc1 +CC(=O)c1cn(CCC(=O)Nc2nnc(C)s2)c2ccccc12 +O=C(c1ccccc1F)N1CCN(Cc2ccsc2)CC1 +CCOC(=O)C1CCN(c2ncc(C(N)=O)cc2Cl)CC1 +CCOc1cc2c(cc1NS(=O)(=O)c1cccs1)OC(C)C2 +COc1ccc(F)cc1C(C)NC(=O)CCc1nc(C(C)C)no1 +C=C(C)Cn1nnc(S(=O)(=O)CC(=O)OCC)c1N +CC(C)C(=O)c1ccc(S(=O)(=O)CC(O)CO)cc1 +NC(=O)CCn1ccc(NC(=O)c2cccc(-n3cccc3)c2)n1 +CCc1cc(Br)cc2c1OCCC(=O)N2C +CC(C)N(CC(=O)NCc1cccnc1)c1ccc(N)cn1 +O=C(Cc1cccc2ccccc12)Nc1ccnn1Cc1ccco1 +CCc1cccc(NC(=O)NCc2ccc(S(C)(=O)=O)cc2)c1 +CC(C)CC(C)NC(=O)c1ccc(OCC(F)F)nc1 +CN(CCc1c[nH]c2ccccc12)C(=O)c1ccc(N)cc1 +CCC(=O)Nc1cccc(NC(=O)NC(C)c2c(C)nn(C)c2C)c1 +Nc1nc(SCC(=O)NC(c2ccc(F)cc2)C2CCCC2)n[nH]1 +C=CCc1ccc(OC(=O)c2ccn(C)c(=O)c2)c(OC)c1 +COc1cc(CCC#N)ccc1OCc1ccccc1 +Cc1ncc(CNS(=O)(=O)c2cccc(S(C)(=O)=O)c2)s1 +CCNc1nnc(-c2nnc3sc4c(n23)CCC4)s1 +O=C(CSc1ccccn1)NCCc1ccccc1 +COCc1ccc(CN(C)Cc2nccs2)cc1 +CN1C(=O)CC(NC(=O)Cn2cccn2)C1c1ccc(Cl)cc1 +C=CCc1cc(CNc2ccon2)cc(OC)c1O +CCc1noc(C2CC(=O)N(c3ccccc3F)C2)n1 +CCc1ccccc1CNC(=O)Cn1ccccc1=O +Cc1cc(NC(=O)c2ccc[nH]2)n(Cc2ccccc2)n1 +Cc1cc(CN(C)C(=O)c2ccc(N(C)C)nc2)no1 +CC(C)C(=O)NC(C)c1ccc(S(=O)(=O)N(C)C)cc1 +COCCn1cnnc1SCC(=O)c1ccc(Cl)c(Cl)c1 +CCOc1ccc(CN(C)C(=O)c2cc(F)cc(F)c2)cc1 +CCCCCCNC(=O)Nc1ccc(C(=O)N2CCOCC2)cc1 +Cc1csc(=O)n1CCC(=O)Nc1ccc(-c2cnco2)cc1 +CC(C)(C)C(=O)NCCC(=O)Nc1ccccc1Cl +COCc1cc(CN(C)C(=O)c2c[nH]nc2-c2cccc(F)c2)n[nH]1 +COc1cccc(OC(C)CNC(=O)N2CCOCC2C2CC2)c1 +O=C(c1ccc(F)cc1)N1CCSc2nnc(-c3ccco3)n21 +Cc1cccc(C(C(=O)NCc2cc(=O)[nH]c(C)n2)N(C)C)c1 +Cc1noc(C)c1CNC(=O)Nc1ccc(N2CCOC2=O)cc1 +CC(C)CCn1ccc2nc3ccn(-c4ccn[nH]4)c(=O)c3cc2c1=O +CC1=NC(=O)C2(CCN(C(=O)OCC(C)C)CC2)N1 +CSc1sc(NC(=O)Cc2cccc(OCC#N)c2)nc1C +CC(=O)NCc1ccc(C(=O)CSc2cccc(Cl)c2)s1 +Cc1cccc(C(C)CNC(=O)Cc2c(C)[nH]c3ccnn3c2=O)c1 +Cc1ccc(C)c(NC(=O)NC2CCN(c3ccccc3)C2=O)c1 +CC(C)Oc1cccnc1C(=O)NCc1cn(-c2ccccc2)nn1 +Nc1ccc(F)c(NC(=O)c2c(F)cccc2F)c1 +CC(C)(C)C(NC(=O)Cc1ccn(-c2ccc(F)cc2)n1)C(N)=O +Cc1nn(CC(=O)N(c2ccccc2)C(C)C)c(C)c1Cl +COCC1CN(c2ccc(Cl)cc2C#N)CCO1 +Cn1ncc(N2CCOC(CCNc3cc(N)nc(N)n3)C2)cc1=O +Cc1nc(-c2ccc(CNC(=O)c3ccc(=O)[nH]c3)o2)cs1 +Cc1c(Br)cccc1COC(=O)c1ccc(=O)n(C)c1 +COC(=O)c1ccc(Cn2nnc(C#N)c2C(F)(F)F)cc1 +Cc1ccsc1CNC(=O)c1c(C)nc(C(C)(C)C)[nH]c1=O +Nc1cccc(C(=O)CCNc2ccc(F)c(Cl)c2)c1 +Cc1csc(C(C)NC(=O)c2c(C)cc(C)[nH]c2=O)n1 +NC(=O)CSc1nnc(-c2ccccc2F)n1Cc1ccco1 +CCN(CC)C(=O)CCC(=O)N1CCC(Nc2ccccc2F)CC1 +Cc1noc(C)c1C(=O)Nc1cccnc1N1CCCC1 +O=C(Cc1ccc2ncccc2c1)c1ccc(O)cc1O +O=C(Cc1ccccc1)NCC#Cc1ccc(F)cc1 +Cc1nc(C)c(C(=O)NC2CC(=O)N(C)C2)s1 +CCn1c(=O)n(Cc2csc(C)n2)c2ccccc21 +O=C(COC(=O)c1cnccn1)Nc1ccc(F)c(Cl)c1 +CC(C)Cc1nnc(NC(=O)NC(C)C(=O)N2CCCCC2)s1 +Cn1ccc2cc(C(=O)NCc3nc4ccccc4n3C)ccc21 +Cc1cnn(-c2ccc(C(=O)N3CCc4cc(F)ccc4C3)cc2)c1 +CC(=O)NCCNC(=O)c1ccnc(-n2ccnc2)c1 +Cc1ccc(NC(=O)CSc2cc(-n3cccn3)ncn2)c(F)c1 +NC(=O)NCC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +Cc1cccc(OC(C)C(=O)C(C#N)c2nc(C)cc(C)n2)c1 +CS(=O)(=O)Nc1cccc(C(=O)Nc2ccc(CC#N)cc2)c1 +CC(=O)c1csc(NC(=O)c2ccc(F)cc2F)n1 +Cc1cc(S(=O)(=O)N(C)C(=O)C2CC2)ccc1Br +CCn1cc(NC(=O)NCc2cccc(N3CCCC3=O)c2)cn1 +Cc1ncc(CNC(=O)c2c[nH]c3cccc(F)c23)s1 +Cc1cccc2[nH]cc(CC(=O)OCC3CC(=O)N(C4CC4)C3)c12 +CC1CCC(NC(=O)c2ccc3c(c2)nnn3C)CC1 +C=CCN(CC=C)C(=O)CCc1c(C)nn(C)c1C +CCCC(C)(CO)NC(=O)NCCN1CCOCC1 +COc1ccc(-c2cc(C(=O)N3CCCC3)n(C)n2)c(F)c1 +Cc1ccc(C)c(N2CCN(Cc3ccccn3)CC2)c1 +O=C(c1ccoc1)N1CCC(c2c[nH]c3ccccc23)CC1 +COCCn1c(C)cc(C(=O)Cn2nnc3ccccc3c2=O)c1C +Cc1ccc(-c2cc(C(=O)NC(C)CO)on2)cc1 +COCCN1CCN(Cc2csc(Cc3ccccc3)n2)CC1=O +CCc1nnc(SCCC(=O)Nc2ccccc2)o1 +CCOCC1CCCN(C(=O)CCc2nc3ccccc3s2)C1 +CCC1CCCCN1C(=O)C(C)Sc1nccn1C +Cc1cccc(C(=O)NCc2ccc(CN3CCCC3=O)cc2)c1O +CCC(C)(C)NC(=O)CSc1nnnn1-c1ccc(C)cc1 +COCc1cccc(C(=O)NCc2csc3c2CCCC3)n1 +Cc1ccc(NS(=O)(=O)c2ccc(N)cc2)nc1 +CC(=O)NCCNc1cc(N)nc(SCc2ccccc2C)n1 +CC(C)C(N1CCCCCC1=O)n1nnc2ccccc21 +COc1cccc(C(=O)NCC(F)(F)F)c1F +CC(NC(=O)COC(=O)c1ccc(O)cc1O)c1ccccc1 +N#Cc1ccc(CN2CCOC(C3CCCO3)C2)cc1 +COc1ccc(C(=O)Nc2ccc(OC(C)=O)cc2)cc1 +Cc1nn(C)cc1C(=O)OCCN(C)C(=O)OC(C)(C)C +Cn1c(=O)c2c(Nc3cccc(F)c3)ccnc2n(C)c1=O +Cc1cccc(CN2CCN(c3ccccc3)C(=O)C2)n1 +Cc1cc(-c2nnc3n2N=C(c2ccccc2)CS3)n[nH]1 +CCCCCC(=O)N1CCN(c2ncccn2)CC1 +CCn1c(C)nnc1SCCC(=O)c1ccc(F)cc1 +CCC(C)n1c(C)c(C)n2c3c(=O)[nH]c(=O)n(C)c3nc12 +CC(C)N1CC2(CCC1=O)CCN(C(=O)C(O)c1ccccc1)CC2 +CNc1ccc(N(C)S(=O)(=O)c2cccs2)cc1C +Cc1ccccc1Cn1cnc(NS(=O)(=O)c2cnn(C)c2)n1 +CC(=O)NCc1ccc(C(=O)NCCc2cn3ccccc3n2)cc1 +Cc1ccc(NC(=O)Cn2nc3c(cc2=O)CCCC3)c(C)c1 +Cc1nccn1C1c2ccccc2CSc2sccc21 +Cc1cccc(S(=O)(=O)C(C)C(=O)NC(C)(C)C)c1 +Cn1ccc(NC(=O)c2ccc(-c3cscn3)cc2)n1 +CC(Oc1cccc(F)c1)C(=O)Nc1ccc(Br)cn1 +CN1CCN(C(=O)CCC2CCCC2)c2cccnc21 +CCOc1ccc(C(=O)NCC(=O)Nc2ccc(F)cc2C)cc1 +O=C(CCn1cnc2sccc2c1=O)N1CCC2CCCCC2C1 +COc1cc2c(cc1OC)CN(C(=O)Cn1nc(C)cc1C)CC2 +NC(=O)NCc1ccc(C(=O)Nc2cccc3cccnc23)cc1 +COc1ccc(NC(C)=O)c(NC(=O)c2cc(C(C)=O)cn2C)c1 +Cc1nc(COC(=O)c2cnn(CC(C)C)c2C2CC2)c(C)s1 +CC(=O)NCC(=O)NC(Cn1nnc2ccccc21)C(C)C +CNS(=O)(=O)c1cc(S(=O)(=O)NC)c(Cl)cc1N +COc1ccc(NCc2ccc(F)c(Br)c2)cn1 +CC(=O)N1CCN(c2cc(Nc3ccccn3)ncn2)CC1 +CC(=O)c1ccccc1NC(=O)CSc1nnc(NC2CC2)s1 +CNC(=O)c1cccc(CNC(=O)c2oc3c(C)cccc3c2C)c1 +O=C1CN(Cc2ccccc2)C(c2cnc(-c3ccsc3)s2)N1 +COc1cc(N)ccc1NC(=O)C(C)OCC1CC1 +CS(=O)(=O)N(CCCN1CCOCC1)Cc1ccncc1 +CC(C)Nc1nnc(SC(C)C(=O)NC(C)(C#N)C(C)C)s1 +COC(=O)c1cccc(NC(=O)NCc2ccncc2)c1 +Cc1c(Cl)cccc1NC(=O)CCN1C(=O)COc2ccccc21 +O=C(CN1CCN(C(=O)CN2CCOCC2)CC1)N1CCCCC1 +COC(=O)c1ccsc1NC(=O)CSc1nnc(C)s1 +COc1ccccc1NC(=O)c1ccc2c(c1)CCC(=O)N2 +COCCCNC(=O)Nc1ccc(C)c(Br)c1 +COc1cc(OC)cc(C(=O)Nc2cc(C)nn2C(C)C)c1 +CCCCCNC(=O)NC(c1ccccc1F)c1nccn1C +CCOc1ccccc1NC(=O)c1sc(-c2ccccn2)nc1C +COC(CNS(=O)(=O)c1ccccc1Cl)c1ccc(C)s1 +CCn1cc(C(=O)NCC(C)(C)C(N)=O)c(C(C)C)n1 +Cc1cc(Br)c2nc(-c3cccc(N)c3)cn2c1 +O=C(Oc1cccc(Oc2ncccn2)c1)c1ccc(F)nc1 +CC(C)(C)OC(=O)N1CCc2c(cccc2NCc2ccon2)C1 +COCCCNC(=O)C1CC(=O)N(c2ccc(F)cc2)C1 +Cc1cc(C)cc(C(=O)Nc2ccc3c4c(c(=O)[nH]c3c2)CCC4)c1 +Clc1cccc(CN2CC(c3nc(-c4ncccn4)no3)C2)c1 +CC(O)CN(C)C(=O)c1coc(COc2cccc3cccnc23)n1 +COc1ccccc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +CCN(CC)S(=O)(=O)c1ccc(C)c(Br)c1 +CC(C)N(C)C(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +Cc1cn(CC(=O)N2CCc3ccccc3C2)c(=O)[nH]c1=O +Cc1cc(C(=O)Nc2cc(-c3ccncc3)n[nH]2)on1 +CCOc1ccccc1C(=O)N1Cc2cncnc2C1 +CC(=O)Nc1ccccc1OCC(=O)N(C(C)C)C(C)C +CCc1ccc(CN(C)C(=O)c2nc3nc(C)cc(C)n3n2)nc1 +Cc1cc(C)c2c(n1)oc1c(NCc3cccnc3)ncnc12 +CS(=O)(=O)Nc1ccccc1NC(=O)Cc1c[nH]c2ccccc12 +CC(OC(=O)C(c1ccccc1)N1CCCCC1=O)c1ccccn1 +COc1cccc(-c2cc(=O)c3ccc(O)cc3o2)c1 +CCCS(=O)(=O)NC(C)C(=O)NCc1cn[nH]c1 +COc1cc(N2CCC(Oc3cccc(F)c3)CC2)nc(N)n1 +Cc1cccnc1NC(=O)NC1CCSc2ccc(F)cc21 +COC(=O)c1nnn(CCCOc2ccc(C)cc2)c1N +Cc1cc(C(=O)N2CCOCC(Oc3ccccc3)C2)no1 +CC(NC(=O)Cn1ccc(=O)n(C)c1=O)c1cccnc1 +CCSc1ccccc1C(=O)Nc1cc(C(C)(C)C)nn1CCO +COCCN(C)C(=O)Cc1csc(-c2ccc(C)cc2)n1 +O=C(Cn1cnnn1)NCc1cccc(C(=O)NCc2ccco2)c1 +O=C(Cc1ccsc1)Nc1nc(-c2ccccn2)cs1 +CC(=O)Nc1ccc(C(=O)NCCOc2cccc(C)c2)cc1 +CCCCS(=O)(=O)Nc1ccc(NC2CC(C)OC2=O)cc1 +COc1ccc2c(c1)C(c1cccc(O)c1)NCC2 +COc1ccc(-n2cc(C(=O)c3ccccn3)nn2)cc1 +Cc1ccc(C)c(OCc2nnc(SCC(=O)N3CCCC3)o2)c1 +CCCn1c(C)nnc1COc1cccc2nc(C)ccc12 +Cc1nc(C(=O)N2CCC3C(CCC(=O)N3CCCCO)C2)c(C)o1 +O=C(Nc1cccc(N2CCCS2(=O)=O)c1)c1ccco1 +Cc1noc(CNC(=O)c2ccc(-n3cccc3)cc2)n1 +N#Cc1cc(NCC(=O)N2CCNC(=O)C2)ccc1F +COCCNC(=O)CN1CCN(c2ccc(F)cc2C#N)CC1 +CC(=O)c1c(C)n(C)c2cccc(Br)c12 +O=C(CC1CCCO1)Oc1ccc2nccnc2c1 +Cc1csc(NC(=O)c2nccc3c(N)ccc(Cl)c23)n1 +O=C(CNC(=O)c1cc2ccccc2[nH]1)NCc1cn2ccccc2n1 +Cc1ccc(F)cc1NC(=O)N1CCCCC1CCN1CCOCC1 +Cc1ccnn1-c1ccc(C(=O)N2CC=C(c3ccccc3)CC2)cc1 +Cc1ccc(CNC(=O)NCC2CCCO2)s1 +Cn1cc(Cl)cc1C(=O)NCC(=O)Nc1ccccc1 +Nn1c(SCC(=O)OC2CCCC2)nnc1-c1ccccc1 +CCOC(=O)c1cnc(C(C)C)nc1-c1ccccc1C +O=C(NCCc1ccccn1)c1ccc(COc2ccc(F)cc2)o1 +Cc1ccccc1CN(C)C(=O)c1ccc(-n2cccn2)cc1 +C=CCN(Cc1ccc(C#N)cc1)C(=O)c1[nH]c2c(c1C)C(=O)CCC2 +CCOC(=O)CC(C)CNC(=O)Nc1ccc(Br)cc1 +CN(Cc1ccco1)C(=O)NC1CCC(O)CC1 +Cc1nc(C2CN(Cc3nc(C(C)(C)C)cs3)CCO2)no1 +COC(=O)CCNc1cc(C)c(Cl)cc1OC +Cc1cccc(-c2ncc(C(=O)NC3CC3)c(N3CCCCC3)n2)c1 +COc1ccc(C(=O)NC(C)c2cnn(-c3ccccn3)c2C)o1 +Cc1ccc(-n2nnc(CO)c2C(C)(C)C)cc1F +Cc1cc(C)cc(OCc2ncc(CC#N)s2)c1 +CCCN(CC(F)F)C(=O)c1cnc(C2CCCO2)s1 +CC(C)Oc1ccc(-c2nc(C(=O)N(C)CCC#N)cs2)cc1 +O=C(NCC1CCCO1)c1ccc(-c2cccnc2)nc1 +Cc1ccc(NC(=O)N2CCCC(O)C2)cc1Cl +c1ccc(-c2ccc3nnc(C4COCCN4)n3n2)nc1 +CCc1cc(C(=O)NCCCN2CCCC2=O)[nH]n1 +CCOc1ccc(CC2(c3ccc(OC)cc3)NC(N)=NC2=O)cc1 +O=C(COc1ccccc1Cl)NCc1nncn1-c1ccccc1 +COC(=O)C1(NC(=O)c2ncn(-c3ccccc3)n2)CC1 +Cc1cccc2c1C(C(=O)N1CCCCC1)CNC2 +CCc1ccc(CN2CCc3onc(-c4cccc(OC)c4)c3C2)nc1 +Cc1ccc2nc(C)c(NC(=O)c3ccc(F)cc3)c(=O)n2c1 +O=C(Nc1ccc2c(c1)OCO2)N1CCN(Cc2ccncc2)CC1 +COc1cc(NC(=O)N(C)CCO)cc(OC)c1 +CCc1cccc(C)c1NC(=O)C1CC(=O)N(Cc2ccccn2)C1 +Nc1ccc(C(=O)CCC(=O)Nc2cccc(Cl)c2)cc1 +CC1CCCC(OC(=O)c2ccc(Cn3ccccc3=O)o2)C1 +CC1CN(Cc2cc(C(N)=O)cs2)CC(c2ccccc2)O1 +CN1C(=O)CC(C(=O)N2CCOC(C)(C)C2)C1c1cccnc1 +CC(C)CN1CC(C(=O)Nc2nccs2)CC1=O +CCCCCCNC(=O)C(N)c1ccccc1F +COc1cccc(C(C)NS(=O)(=O)c2cnn(C(C)C)c2)c1 +Cc1ccc(CNC(=O)NCC(C(C)C)N2CCOCC2)cc1 +Cc1ccc(CC(C)N(C)S(=O)(=O)c2cccnc2)cc1 +Cc1ccnc(NC(=O)C(C)n2nc(-c3ccccc3)ccc2=O)n1 +CC(C)c1nnc(NC(=O)c2ccc3c(c2)OCO3)s1 +CC(NC(=O)c1cnc2c(cnn2C(C)C)c1)c1ccncc1 +Cn1ncnc1-c1ccnc(N2CCCC(F)(F)C2)n1 +CCOC(=O)Cc1c(C)nn(-c2nncn2N)c1C +O=C(Cc1ccccc1)c1cccc(C2OCCO2)c1 +COc1ccc(CCNC(=O)c2cn3ccc(C)cc3n2)cc1 +CSc1ccc(NC(=O)c2ccc(C)[nH]c2=O)cc1 +Cc1ccc2c(Nc3ccc(S(N)(=O)=O)cc3)cc(C)nc2n1 +CC(=O)N1CCN(C(=O)c2cnn3ccccc23)CC1 +CC(C)CNC(=O)NCCn1nnc2cc(C(=O)NC(C)C)ccc21 +CC(C)OC(=O)C(C)CNC(=O)c1ccc(-n2ccnn2)cc1 +CC(=O)Nc1ccc(C(=O)Oc2ccc(C(C)=O)cc2)s1 +O=C(Nc1nccs1)Nc1cccc2ccccc12 +N#Cc1cnc(SCc2ccc(OC(F)(F)F)cc2)nc1N +O=C(NCCNC(=O)c1ccccc1O)c1cc(-c2ccco2)[nH]n1 +Cc1cc(OS(=O)(=O)N(C)C)cc(C)c1Cl +Cc1sc(NC(=O)c2ccncc2)nc1-c1cccc(Cl)c1 +CN(C)C(=O)c1ccnc(NCc2cccc(C#N)c2)c1 +CCOC(=O)C1=C(C)C(S(=O)(=O)NCc2ccccn2)C(C)=N1 +O=C(NCc1n[nH]c(=O)[nH]1)c1c[nH]nc1-c1ccccc1F +O=C(Nc1cc(Br)ccc1-n1cccn1)c1cccs1 +CC(C)CNC(=O)c1ccc(Cl)c(NC(=O)C2CC2)c1 +COC(=O)Nc1ccc(CNC(=O)CCn2cncn2)cc1 +Nc1cc2c(cc1-n1cc(Br)cn1)OCCO2 +COCCC(C)NC(=O)N1CCC(n2ccc(C(F)(F)F)n2)CC1 +Cc1nc(CN2CCc3ncnc(-c4ccoc4)c3CC2)cs1 +Cc1cc(C(=O)N(C)c2ccccc2)ccc1NS(C)(=O)=O +O=C(CCn1ccccc1=O)N(Cc1ccc(F)cc1)C1CC1 +COC(=O)c1cccc(CNc2ccccc2-n2cccn2)c1 +Cc1ccn(CC(=O)N2CCCC(C)C2)c(=O)c1C#N +Cc1ccc2[nH]nc(C(=O)Nc3ccc(NC(=O)NC4CC4)cc3)c2c1 +COCc1nc(COc2ccccc2C)sc1C#N +Cc1ccc(C)c(C(C)Nc2ncccc2S(N)(=O)=O)c1 +COc1ccc(C(=O)Nc2cnc3c(c2)c(C)nn3C)c(OC)c1 +Cc1ccc(NCc2cnn(C)c2)cc1Br +Fc1ccc2c(c1)nc(NCc1ccncc1)c1nccn12 +N#Cc1cccc(NC(=O)C(Cc2ccccc2)NC(N)=O)c1 +Cc1cc(Cl)ccc1OCC(=O)NCCNC(=O)C1CC1 +COCCN1CCN(Cc2csc(C(C)C)n2)CC1=O +O=C(OCCCn1c(=O)[nH]c2ccccc21)c1cc2ccccc2[nH]1 +COc1ccc2c(=O)n(Cc3nc(-c4ccco4)no3)cnc2c1 +Cc1cccc(N2CCN(C(=O)Nc3ccc4c(c3)COC4)CC2)c1 +COc1cccc(-c2nc(COC(=O)c3cc[nH]n3)cs2)c1 +Cc1nnc(CC2COCC3CN(C(=O)c4ccoc4)CC23)o1 +O=C(CCc1ccccc1)N1CCCN(C(=O)c2ccon2)CC1 +COc1ccc(C(=O)CCNc2cccc(F)c2)cc1 +O=C(C1CCCC1)N1CCC(c2nnc3n2CCCCC3)CC1 +CCn1c(C)nnc1SCCNc1cc(N2CCOCC2)ncn1 +CSc1ccccc1NC(=O)c1cn2ccc(C)cc2n1 +N#Cc1nc2cc(C(F)(F)F)ccc2n1CC(F)(F)F +COCCNC(=O)CN1CCN(c2ccc3nncn3n2)C(C)C1 +COC(=O)CSc1nccc(N2CC(C)CC(C)C2)n1 +CCNC(=O)c1cnc(-c2c(F)cccc2Cl)nc1N +Cc1ccc2ncc(C(=O)Nc3n[nH]c(C)n3)n2c1 +COCCn1c(=NC(=O)c2ccno2)sc2ccccc21 +CC1CN(C(=O)CNc2ccccc2C(F)(F)F)CC(C)O1 +CC(=O)NC(C)(C)c1noc(-c2cccc3c2OC(C)C(=O)N3)n1 +C=CCCCN(C)C(=O)Nc1ccc(F)c(C#N)c1 +CCCN(Cc1cccnc1)C(=O)c1sccc1C +Cc1cc(NCc2c[nH]c(=O)[nH]c2=O)nc(-c2ccccc2O)n1 +N#Cc1ccc(C(=O)Nc2ccc(Cl)cc2)c(F)c1 +N#CCCN(C(=O)CCc1ccccc1)c1ccccc1 +CCc1ccsc1C(=O)Nc1cccc(C(N)=O)c1 +NC(=O)C1CCN(C(=O)C2CC2c2ccc(C(F)(F)F)cc2)C1 +NC(=O)c1ccccc1OCC(=O)Nc1ccc2c(c1)OCCO2 +COC(=O)C1CC(Oc2ccc(F)c(Cl)c2)CN1 +Cc1cc(C#CCO)ccc1NC(=O)NC(C)(C)C +CN(CC(=O)NCc1ccnn1C)c1ccc(Cl)cn1 +COc1n[nH]c(-c2cc(C)on2)c1Br +N#Cc1cc(-c2cccc(Br)c2)c[nH]c1=O +O=S(=O)(NCc1csc(-c2ccccc2)n1)c1cccnc1 +Cc1ccc(C(C)NC(=O)c2cc(Br)cn2C(C)C)o1 +NC(=O)c1csc(C(=O)OCc2ccccc2)c1 +CC(C)Cc1noc(COc2cccc(S(C)(=O)=O)c2)n1 +CC(C)NC(=O)c1cccc(CNC(=O)N2CCOC(C)C2)c1 +Cc1ccccc1OCCCn1ncsc1=O +O=C(NCC(=O)N1CCCC1c1cccc(F)c1)C1CCCC1 +CC(C)(CO)n1c(-c2cccc(F)c2)nc2cccnc21 +CC(C)c1ccccc1N1C(=O)C(C)(C)CS1(=O)=O +Cc1cccc(-c2nc(-c3cc4ccccc4o3)no2)n1 +Cc1cccc(CCC(=O)Nc2nnc(C)s2)c1 +CCCc1ccc(NC(=O)C2CC(=O)Nc3cc(F)ccc32)cc1 +O=C(CNS(=O)(=O)c1ccc(Cl)cc1)OCc1ccccc1 +COc1cccc(OCC(=O)Nc2cnccc2C)c1 +CN(CCC#N)C(=O)c1ccccc1Nc1cccc(C(F)(F)F)c1 +CCc1sc(C(=O)NCC2CCCO2)cc1Br +CCc1ccc(Cl)c(CC)c1NC(=O)NCc1cnc(C)s1 +COc1ccc(CCC2CCN(C(=O)c3cnn(C)c3C)CC2)cc1 +O=C(CN1CCOC1=O)NCCc1cccc(F)c1 +CCOC(=O)N1CCc2nc(NC(=O)c3nn(C)cc3C)sc2C1 +Cc1cccc(C2(C(=O)NCCC(=O)N(C)C)CC2)c1 +Cc1cc(N2CCCC(c3noc(C)n3)C2)ncn1 +O=C(Nc1ccn(Cc2ccccn2)n1)C1(c2ccc(F)cc2)CC1 +Fc1c(Cl)ccc2c1CCNC2c1ccoc1 +COC(=O)COc1cccc(NC(=O)Cc2ccccc2F)c1 +CCOc1cc(C(=O)NC2CCCC2)ccc1OC +CCCn1cccc(-c2csc(NC(C)CC)n2)c1=O +Cc1ccc(C(=O)N(C)CC(=O)Nc2cc(C)ccc2C)cc1 +O=C(COn1nnc2ccc(Cl)cc21)N1CCCC1 +O=C(CCC(=O)c1ccc2c(c1)OCCCO2)Nc1cccnc1 +Cn1ccnc1CN1CCCN(C(=O)CCCc2ccccc2)CC1 +COc1ccc(OC)c(NC(=O)CCc2ccccc2N)c1 +O=C(c1cc2ccccc2oc1=O)N1CCC(Cc2ccccc2)CC1 +Cn1c(C(C)(C)O)nc2ccc(C(F)(F)F)cc21 +Cc1ccnc2c1NC(=O)CN2C(=O)c1ccc(Br)cc1 +COc1ccccc1CCNC(=O)c1csc(-n2cccc2)n1 +Cn1ccnc1C(NC(=O)CC(C)(C)C)c1ccccc1F +CCn1cc(Br)cc1C(=O)NCC1CCCCO1 +CC(=O)Nc1ccc(C(=O)NCCCn2ncccc2=O)cc1 +CCC(C)C(NC(=O)N1CCN(C(C)=O)CC1)C(=O)OC +CNC(=O)CNS(=O)(=O)c1ccc(N)cc1Cl +Cc1nn(C)c2ncc(NC(=O)c3ccc(Cl)cc3)cc12 +Cc1cn2c(=O)c(C(=O)N3CC4OCCN(C)C4C3)cnc2s1 +COc1cccc(C(=O)N2CCN(Cc3c[nH]c4ccccc34)CC2)c1 +Cc1cc(NC(=O)c2ccco2)sc1C(=O)N1CCCC1 +CCCN(C)S(=O)(=O)c1cccc2c1CCNC2 +O=C(Nc1ccc(-c2cnco2)cc1)c1cnn(-c2ccccc2)c1 +O=C1CCC2(CCOC2)CN1CCc1nc2c(s1)CCC2 +O=C(CCNC(=O)N1CCc2sccc2C1)N1CCCC1 +Cc1ccc(-c2ncco2)cc1NC(=O)N1CC(CO)OCC1C +Cc1ccc(-n2nc(C)cc2NC(=O)c2cccc3ncccc23)nn1 +CCc1nc2ncc3c(n2n1)CC(c1cccc(Cl)c1)CC3=O +CC(C)(C)c1csc(CCNC(=O)c2ccc3[nH]nnc3c2)n1 +CN1CC(=O)N2CCN(c3ccc(C#N)cn3)CC2C1=O +c1ccc(Cn2cnc3cc4c(cc32)OCCO4)cc1 +Cc1cc(C)c(S(=O)(=O)NC(C)Cn2nc(C)cc2C)c(C)c1 +CCOC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1c(C)cc(C)cc1C +COc1cc(C(=O)N2CCCC2C(=O)NC2CC2)cc(OC)c1C +CC(=O)NC(C)(C)C(=O)NC(C)C(c1ccccc1)c1ccccc1 +Cn1cc(CN2CCCn3c(nc(CN4CCCC4)cc3=O)C2)cn1 +Cc1noc(C)c1CC(=O)OCc1ccccc1F +COC(=O)C1CCN(c2nc[nH]c(=O)c2N)CC1 +CC(Nc1cc(C(N)=O)ccc1Cl)c1ccccn1 +COCc1nnc(SCC(=O)Nc2ccc(OC)cc2C)n1N +CC1Cc2ccccc2N1C(=O)NCCc1nnc2n1CCCCC2 +CC(NC(=O)c1cccc(Cl)c1)c1ccc(S(N)(=O)=O)cc1 +O=C(NCC#Cc1ccc(N2CCOC2=O)cc1)c1ccsc1 +CCOc1ccc(S(=O)(=O)Nc2cccc(C(=O)NC)c2)cc1 +Cc1ccc(F)c(S(=O)(=O)NCc2nnc3n2CCCCC3)c1 +Cc1nc(N(C)C)ncc1C(=O)N1CCc2ncccc2C1 +CCOc1ccc(CC(=O)N(CC)Cc2cnc3ccccn23)cc1 +O=C(c1ccc(OCC2CC2)cc1)N1CCCS1(=O)=O +COc1ccc(C)cc1NC(=O)c1cccnc1N +Brc1cnc(C=Cc2ccccc2)nc1 +CCNC(=O)NCCc1c(Cl)cccc1Cl +Cc1cc(C)n(-c2ccc(Cl)c(C(=O)N(C)CCC#N)n2)n1 +Cc1cc(CNC(=O)Cc2ccccc2)nc(N2CCOCC2)n1 +CC(=O)Nc1ccc(CN2CCOC(c3ccc(C)cc3C)C2)cc1 +Cc1ccc(Cn2nccc2NC(=O)c2cccc(C#N)c2)o1 +CC(NC(=O)c1cn(C)nc1C(C)(C)C)c1cnn(C)c1 +CC(C)(C)OC(=O)NCCc1nc(-c2ccccn2)no1 +CCC(=O)c1ccc(S(=O)(=O)NC2CCCC2)cc1 +COC(=O)c1cccc(NC(=O)Cc2ccc(C)nc2)c1O +O=C(CCS(=O)(=O)c1ccc(O)cc1)Nc1ccc2c(c1)CCC2 +COCCN(CC(C)C)C(=O)c1ccc(N2CCNC2=O)cc1 +CC1=C(C(=O)NCc2ccccc2)C(c2ccc(C)o2)n2ncnc2N1 +O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)N1CCCCCC1 +Cc1cc(C(=O)N2CCN(C3CC3)CC2Cc2ccccc2)c(C)o1 +O=C(Cn1ncc(=O)c2ccccc21)Oc1cccc(F)c1 +N#Cc1nnn(Cc2cccc3ccccc23)c1C1CC1 +CC(=O)c1cccc(NC(=O)Nc2ccc(Oc3cnccn3)cc2)c1 +CN1CC2(CCCN(C(=O)c3cnc4cccnn34)C2)OC1=O +CN(CCC#N)C(=O)Nc1ccc(OCc2ccccn2)c(F)c1 +Cc1noc(C2CN(C(=O)C3(c4ccc(Cl)cc4)CCCC3)C2)n1 +CC(=O)c1cc(C#N)c(SCC(=O)c2ccc(Cl)cc2)nc1C +C=CCNC(=O)NCC(O)COc1ccc(F)cc1 +O=C(NCc1nc[nH]n1)c1cc(Br)ccc1Cl +CC(C)=Cc1nnc(C(N)c2cc(C#N)ccc2F)o1 +CCn1ncc(C2CC(O)=Nc3c2c(=O)[nH]n3C2CCCC2)c1C +CCCn1cc(NC(=O)N2CCN(c3cnn(C)c(=O)c3)CC2)nn1 +C=CCNC(=O)c1ccc(NC(=O)C2(c3ccccc3)CC2)cc1 +O=C(NCc1cccs1)c1ccc(OCC(=O)C2CC2)cc1 +O=C(NC1CCN(c2ccccc2)C1)N1CCCC1 +C=CCNc1ccccc1C(=O)NC(C)Cc1ccncc1 +COC(=O)Nc1ccccc1C(=O)N1CCC(OCC(C)C)CC1 +COC1CCC2C1OCCN2S(=O)(=O)c1cccnc1 +Cc1cc(C)c2nc(-c3cnc(C(C)C)nc3)cc(C(=O)N(C)C)c2c1 +Cc1noc(COCC(=O)NC(C)(C)c2cccc(Cl)c2)n1 +Cn1nnnc1-c1cccc(NC(=O)Cn2ccccc2=O)c1 +Cc1noc(C)c1CCCNC(=O)Nc1cc(Cl)ccc1F +CCNc1ccc(S(=O)(=O)N(C)C(C)C2CC2)cn1 +CCOCc1c(C(=O)Nc2nccs2)oc2ccccc12 +COc1ccc(NC(=O)NCc2ccc(C(C)O)cc2)cn1 +CCCCOc1cccc(CNC(=O)c2cocn2)c1 +Cc1ccc2nc(C(=O)NCc3nncn3C3CCCCC3)cn2c1 +Cc1cc(C)c(C(=O)Nc2ccc(OCC(F)(F)F)cc2)c(=O)[nH]1 +Cc1nnnn1-c1ccc(F)c(NC(=O)c2ccc3ccccc3c2)c1 +C=CCn1c(-c2ccccc2)cc(SC)c(C#N)c1=O +Cc1cc(C(=O)NCc2ccc(F)c(C)c2)c2c(=O)[nH]n(C)c2n1 +COc1cccc(OC)c1COC(=O)c1cc2c(C)nn(C)c2s1 +O=C(CNC(=O)c1cccs1)NCc1ccnc(OC2CCC2)c1 +O=C(NCc1ccccc1OCC1CC1)c1ccnc(-n2cncn2)c1 +CSc1ccc(OC(C)C(=O)NCc2ccccc2F)cc1 +C=CCN(CC(=O)N(C)c1nccs1)Cc1cccs1 +Cc1cccc(CNC(=O)C2Oc3ccccc3OC2C)c1 +O=C(c1ccc(N2CCCCCC2)nc1)N1CCCC1 +CC(O)c1nc2cc(Cl)ccc2n1Cc1ccccc1 +C#CCNC(=O)c1ccc(=O)n(Cc2noc(-c3ccccc3C)n2)c1 +CCC1CCC(NC(=O)Cc2ccc(NC(C)=O)cc2)CC1 +CCc1ccc(CNc2cnn(CCOC)c2)s1 +CC(=O)N1CCN(CCNS(=O)(=O)c2c(F)cccc2F)CC1 +COc1ccc(-c2nc(C)c(CO)s2)c(OC)c1 +O=C(Nc1ccn(Cc2cccnc2)n1)Nc1ccc(F)cc1F +CC1CC1NC(=O)c1cccnc1OCC(F)F +O=C(NCCCN1CCOCC1)N1CCC(c2ccc(O)cc2)CC1 +COc1ccc(CC(=O)N2CCCC2c2cccnc2)c(OC)c1 +Cc1ccc(Cl)cc1NC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +COCCNC(=O)N(C)Cc1cc(Cl)cc(Cl)c1 +Cc1ccc(NC(=O)CSc2nnc(C3CC3)n2C)cc1C +O=C(Nc1cnn(CC2CCCO2)c1)c1cc(F)cc2[nH]cnc12 +CC(C)NC(=O)CCNC(=O)CCc1cc(Cl)cs1 +COc1ccc(OC)c(NC(=O)c2cnn(C)c2-n2cccc2)c1 +CCC1(Cc2ccco2)C(=O)OC(C)(C)OC1=O +CCC(=O)Nc1ccc(O)c(C(=O)NCC2CC2C)c1 +Cc1cc(C)n(-c2ccc(N3CCC4(CC3)OCCO4)nn2)n1 +CCNC(=O)c1ccc(NC(=O)COc2ccc(OC)cc2)cc1 +Cc1cc(CNc2nc3c(c(=O)[nH]2)Cc2ccccc2OC3)no1 +CN(C)C(C(=O)NC1CCOCC1)c1ccccc1F +CC(NC(=O)C(C)(C)C)C(=O)Nc1ccc(NS(C)(=O)=O)cc1 +CC(=O)Oc1ccc(N(C(C)=O)S(=O)(=O)c2cccs2)cc1 +COc1ccc(CNC(=O)Nc2ccccc2Cl)cn1 +Cc1cc(C)c2c(=O)n(Cc3ccccc3C#N)c(=O)n(C)c2n1 +O=C(Cn1c(=O)c2nncn2c2ccccc21)Nc1ccccc1F +Nc1ccccc1OCCCSc1nccc(=O)[nH]1 +CCN(CC)C(=O)Cc1ccc(NC(=O)c2ccc(C#N)cc2)cc1 +CCOCC1CCCN(C(=O)c2cc(C)c(OC(F)F)c(C)c2)C1 +COc1ccc2c(c1)OCC(C(=O)N1CCCC1(C)C)C2 +CC(c1ccccc1)N1CC(C(=O)N2CCc3ccccc3C2)CC1=O +CC(C)(CNC(=O)NCc1cccc(C#N)c1)c1ccncc1 +CS(=O)(=O)N(CC(N)=O)Cc1ccc(Cl)c(Cl)c1 +COC(=O)CCN(Cc1ccncc1)S(C)(=O)=O +CC1=C(c2cccc(Cl)c2)S(=O)(=O)N=C1N1CCN(C)CC1 +CCOC(=O)C1CCN(c2cn3nc(N)nc3cc2C)CC1 +Nc1ccc2c(c1)N(CC(=O)N1CCCCCC1)CCS2 +O=C(CSc1nncc2ccccc12)c1ccc(F)c(F)c1 +O=C(Cn1ncc(=O)c2ccccc21)NCc1ccc(Cl)cc1 +CCSc1ccc(NC(=O)c2cc(OC)c(OC)c(OC)c2)cc1 +Cc1ccc(Cl)cc1NC(=O)c1cc2ccc(O)cc2oc1=O +CCCC(=O)N1CCCC(C(=O)OCc2ccccc2F)C1 +Cc1nc(CC(=O)Nc2cccc3cnccc23)cs1 +CC(Sc1ccccn1)C(=O)N1CCN(C(=O)c2ccoc2)CC1 +Cc1cccc(C(=O)N2CCCC(C(=O)Nc3ccccc3C)C2)c1 +CC(=O)c1ccc(NC(=O)c2cncc3ccccc23)cc1C +O=C(NCC1OCCc2ccccc21)c1nc2ccccn2c1F +Cc1noc(-c2cn3nc[nH]c(=O)c3c2C(C)C)n1 +Cc1cc(CCCC(=O)Nc2nccn(C)c2=O)c(C)s1 +CC(NC(=O)c1ccc(S(C)=O)cc1)c1cc2ccccc2o1 +COCc1cccc(C(=O)Nc2cccc(C)n2)c1 +CCc1nnc(COC(=O)c2cnc(C3CCCO3)s2)n1C +COc1ccc(CCN2CCCS2(=O)=O)cc1Cl +O=C(CSc1nccc(=O)[nH]1)Nc1ccc(O)cc1 +COCCCNS(=O)(=O)c1cc(C)c(C)cc1Br +CN(C)C(=O)CCC1CNc2ccc(F)cc2N1 +CN(C(=O)Cc1cccc(OCc2cccnc2)c1)c1nccs1 +CC(=O)c1ccccc1OCCSc1ncnc2c1cnn2C +CCC(C)NS(=O)(=O)c1ccc(Cl)c(Cl)c1OC +C=CCOc1ccc(C(=O)Nc2cccc(C#N)c2)cc1 +Cc1ccc(CNC(=O)CCc2nc3ccccc3[nH]2)cc1 +O=C(CCOc1ccc(Cl)cc1Cl)NCc1ccco1 +C=CCSc1ccccc1NC(=O)N1CC(C)OC(C)C1 +Cc1cc(C#N)c(NCc2cccc(C)c2F)s1 +CC(CNC(=O)NCCc1nnc2n1CCCCC2)C1CC1 +CCC(O)CN1CCN(C(=O)CN(C)c2ccc(C#N)cn2)CC1 +O=C(Cn1nnc(-c2ccc(F)cc2)n1)NCc1ccc(F)cc1 +COc1cc(C#N)ccc1OCC(=O)NCc1cscn1 +CC1CC(C)CN(C(=O)c2ccc(Cl)cc2N)C1 +C#CCN1CCN(CC(O)COc2cc(Cl)ccc2Cl)CC1 +COC(=O)C1CCCCN1C(=O)c1ccccc1C +O=C(NCCc1nnc2ccccn12)c1cc(Cl)cc(Cl)c1 +COc1ccc(CNC(=O)c2ccccc2C)c(OC)c1OC +Cc1ccc(C)c(Nc2ncnc(NCc3cccnc3)c2N)c1 +CCNC(=O)N1CCCC(c2nnc(-c3ccccc3F)s2)C1 +O=C(Nc1ccc2oc(=O)ccc2c1)N1CCCCCC1 +O=C(NCc1nnc2n1CCC2)Nc1sc2ccccc2c1Cl +Cc1nc2ccccc2n(CC(=O)c2ccc3c(c2)OCO3)c1=O +Clc1ccccc1OCCc1nc2c(s1)CCN2 +CS(=O)(=O)N1CCCCCC1C1CCN(c2ncccn2)CC1 +COCC(C)N1CCN(C(=O)c2cc3ccccc3c(=O)[nH]2)CC1 +CC(C)(C)C(NC(=O)Nc1cnn(-c2ccccc2F)c1)C(N)=O +CCNS(=O)(=O)c1cc(Cl)cc(Br)c1OC +Nc1cc(F)cc(Br)c1OCC(=O)N1CCOCC1 +CCCn1nnnc1Cn1c(C(F)(F)F)ccc(C(N)=O)c1=O +CC(=O)NC(C)C(=O)Nc1ccccc1Sc1ccccc1 +COCC(=O)Nc1cccc(-c2nnc3n2CCCCC3)c1 +O=C(NCCn1cccn1)C1COC(=O)N1Cc1ccc(F)cc1 +CN(C(=O)c1cccnc1OCC(F)F)c1nccs1 +COCCNC(=O)C12CCC(c3nc(C#N)c(C#N)nc31)C2(C)C +CC(=O)Nc1ccc(S(=O)(=O)N2CCC(CO)CC2)cc1 +O=C(c1cccs1)N1CC(C(=O)N2CCc3ccccc32)C1 +CC(=O)N1CCCN(C(=O)Nc2ccc(-n3cnnn3)cc2)CC1 +O=C(COC(=O)c1ccc(O)cc1)Nc1ccccc1C(F)(F)F +CCn1c(N)nc2cc(C(=O)NCCc3nc(COC)no3)cnc21 +Cc1ccc(NC(=O)C(C)n2ncc(-c3ccccc3)nc2=O)cc1C +CCOC(=O)N1CCN(CC(O)c2c[nH]c3ccccc23)CC1 +CN(CC1CCC1)C(=O)NCCc1nccs1 +COc1ccc(S(=O)(=O)n2ccc(C)n2)cc1C(C)(C)C +O=C(Nc1ccccc1F)N1CCN(c2ccc(O)cc2)CC1 +C=CCNC(=O)c1csc(-c2ccccc2OC)n1 +CCOC(=O)C1=C(C)C(C(=O)NCc2ccco2)C(C)=N1 +Cc1cccc2sc(NC(=O)c3cccnc3)nc12 +CC(=O)Nc1ccc(CC(=O)OCC(=O)NC2CCCCC2)cc1 +CC(NC(=O)NCCOc1ccccc1)c1ccccn1 +Cn1ccnc1SCC1CCN(C(=O)c2ccccc2Cl)CC1 +CCC(=O)Nc1cccc(C(=O)Nc2nccs2)c1C +CC(C)S(=O)(=O)N(CC(=O)NC(C)(C)C)c1ccccc1F +O=C(NCc1ccc(C(F)(F)F)cc1)c1cc2scnc2[nH]1 +CCc1nnc(NC(=O)CCCc2nc3ccccc3[nH]2)s1 +Cc1c(NC(=O)NC2Cc3ccccc3C2)cccc1S(C)(=O)=O +CC(C)c1ccc(NC(=O)Cc2cccc(N)c2)cc1 +CC1CN(C(=O)CCCc2ccccc2)CCC1(O)C1CCOCC1 +COCCCNC(=O)NC1CCOc2ccc(Br)cc21 +CCS(=O)(=O)N1CC(C(=O)N2CCCC2)C2(CCOCC2)C1 +CC(N)C(=O)OCCc1ccc(Cl)c(Cl)c1 +OC1Cc2ccccc2C1Nc1nccc(-c2cccnc2)n1 +NC1=NC(=O)C(Cc2ccc(Cl)cc2)(c2cccc(Cl)c2)N1 +N#Cc1cccnc1Nc1ccccc1Br +CC(C1CC1)N(C1CC1)S(=O)(=O)c1ccc(C(N)=O)cc1 +COc1ccccc1C(=O)Nc1cc(=O)oc2ccccc12 +O=C(Nc1ccc(Cl)cc1F)c1cc(F)ccc1-n1ccnc1 +O=C(Cn1ccccc1=O)NCc1ccccc1OC(F)(F)F +O=C(c1ccc(O)c(Cl)c1)N1CCC(c2n[nH]c(C3CC3)n2)CC1 +COC(=O)c1ccc(-c2nc(C)no2)c(Br)c1 +COCCC1NCCc2c1ccc(Cl)c2Cl +O=C(NCc1ccc(-n2cccn2)nc1)Nc1cccnc1 +CC(C)Oc1cccc(C(O)CNC(=O)C2(C)CC2(Cl)Cl)c1 +Cc1cc(C)n2nc(C(=O)Nc3ccccc3C(C)C)nc2n1 +CN(Cc1cc2ccccc2o1)C(=O)Nc1cccc(C(N)=O)n1 +COc1ccc(C(=O)CCN2CCOCC2)c(OC)c1OC +O=C(Nc1ccc2[nH]c3ccccc3c2c1)C1CCCO1 +CC(=O)c1cnc(Nc2nc(C)c(C)s2)nc1C +COc1ccc(C(=O)c2ncccc2C)c(OC)c1 +Cc1c(C)n2c3c(=O)[nH]c(=O)n(C)c3nc2n1Cc1ccccc1 +CC(C)(C)C(=O)CNC(=O)c1ccccc1Cl +CCCc1cc(NC(C)Cn2cncn2)n2nccc2n1 +CCN(CC)C(=O)c1cc(C(=O)NC2CCCC(C)C2C)n(C)n1 +c1cncc(-c2noc(CNc3cc(N4CCOCC4)ncn3)n2)c1 +COC(=O)c1cc(C(=O)Nc2cccc(N3CCCC3=O)c2)ccn1 +N#CCc1ccc(NC(=O)CCC(=O)N2CCOCC2)cc1 +Cc1n[nH]cc1CNc1ccc(C(=O)N(C)C)cc1 +CC(CO)Nc1ncnc2c1cnn2-c1ccccc1 +COc1ccc(OCCN(C)C(=O)c2ccccc2F)cc1 +CC(C)c1ccc(OCC(CC#N)N2CCCC2)cc1 +COC(=O)C1CCN(c2ncnc(Nc3cccc(C)c3)c2N)CC1 +CCn1nc(C)c(NCc2cc3ccccc3o2)c1C +Cc1csc(CN2CCC3OCCC3(C(=O)NCC3CC3)C2)n1 +Nc1cc(C(=O)NC2CC2)ccc1OCCCc1ccccc1 +Cc1ccc(C(=O)Nc2cnn(-c3ccccc3F)c2)c(=O)[nH]1 +OCCc1cnn(Cc2csc(-c3cccs3)n2)c1 +Cc1occc1C(=O)Nc1ccc(NC(=O)Nc2ccccc2)cc1 +CCc1cc(C#N)c(NC(=O)c2cccc(N(C)C)c2)s1 +COc1ccc(CCNC(=O)COc2cccc3cccnc23)cc1 +Cc1csc(NC(=O)C2CC(=O)N(c3ccc(F)cc3)C2)n1 +CC(C)(C)CC(=O)NCc1noc(-c2ccc(F)cc2)n1 +CN(C)c1nc2ccc(NC(=O)c3cn(C)nc3C(C)(C)C)cc2o1 +CC(C)COc1ccc(CNC(=O)c2ccoc2)cc1 +CCN(CC)S(=O)(=O)c1cc(C(C)=O)ccc1C +CCc1nc(CNc2cc(C)ccc2NC(C)=O)no1 +COc1ccc(C(=O)COC(=O)c2ccc(OC)c(N)c2)cc1 +O=C(Nc1cccc(C(F)(F)F)c1)c1cn2cccnc2n1 +COC(=O)Cn1c(C2CCCCC2)nc2c(N)cccc21 +CN(C)S(=O)(=O)NC1CC(=O)N(c2ccc(Cl)cc2)C1 +Cc1ccccc1CCC(=O)Nc1cccc(O)c1 +Cc1csc(C2(NC(=O)CCc3c(C)nn(C)c3C)CCCC2)n1 +O=C(NCC1(c2cccs2)CCOCC1)Nc1ccccc1 +Cc1ccccc1NC(=O)c1ccc(Cl)c(N2CCCC2=O)c1 +CC(C)(C)C(=O)NCCc1nnc2n1CCCCC2 +Cc1nnc(C(=O)Nc2ccccc2)n1-c1ccccc1 +Cc1cc(-c2ccccc2)n(-c2ccc(C(=O)N3CCCCC3)cc2)n1 +CCC(C(=O)Nc1cc(N2CCCC2)ncn1)c1ccccc1 +Cc1cc2ncn(S(=O)(=O)c3ccc(F)cc3)c2cc1C +CNC(=O)Cn1ccc2ccc(NC(=O)NCc3ncn(C)n3)cc21 +O=C(NCc1ccc(-c2nc3ccccc3o2)cc1)c1cccnc1 +O=C(NCCCn1cccn1)Nc1cc(Cl)ccc1F +CCc1nc(NCC2CCCO2)c2c3c(sc2n1)CCC3 +Cc1nonc1CN(C)C(=O)c1ccccc1NCc1cccs1 +Cc1ccc(C(=O)CCC(=O)Nc2ncccc2C)cc1 +O=C(NCCOCC(F)(F)F)c1ccsc1 +O=C(CCNc1ncccn1)Nc1cnn(-c2ccccc2Cl)c1 +Cc1cccc(COCC2CC3(CCN(C(=O)N(C)C)CC3)CO2)n1 +NC(=O)CC1CCN(c2ccc(Br)cn2)CC1 +CN(C)C(C(=O)NCc1cnn2cccnc12)c1ccc(F)cc1 +Cc1cc(NC(=O)NC2CCc3[nH]ncc3C2)ccn1 +CC(=O)N1CC(C(=O)N2CCN(c3cccc(C)c3)CC2)C1 +CCC(Oc1ccccc1F)C(=O)NCc1cccnc1 +O=C(Nc1ccc(Cl)c(Cl)c1)Nc1ccon1 +COC(=O)NCC(=O)N(C)CCOc1cc(C)cc(C)c1 +CCCCNC(=O)c1snc(S(=O)(=O)CC)c1N +CNS(=O)(=O)c1ccc(-c2ccc(NC(C)=O)cc2)cc1 +O=C(Nc1cnn(CC(F)F)c1)N1CCCCCC1c1ccco1 +C=CCNS(=O)(=O)c1cnc(NC2CC2)c(C)c1 +N#CCCSc1nccn1CCc1c[nH]c2ccccc12 +CN(CCNC(=O)Nc1c(F)cccc1F)c1ccccc1 +NC(=O)c1ccsc1NC(=O)CSc1ccccc1 +CCN(CC(=O)N=c1[nH]nc(-c2ccccn2)[nH]1)c1ccccc1 +Cc1ccc(C(=O)CCC(=O)NC2CCSc3ccccc32)s1 +Cc1ccc(-n2cc(C(=O)N(CCO)Cc3ccccc3)nn2)cc1 +CCc1cc2c(Sc3nnnn3-c3ccccc3)ncnc2s1 +CN(c1cccnn1)C1CCN(C(=O)C2(C#N)CCCCC2)CC1 +COC(=O)c1cc(COc2cccc(CC(N)=O)c2)c(C)s1 +COc1ccc(C(=O)NCC(=O)N2CCCC2)cc1 +Nc1ccccc1S(=O)(=O)NCc1ccccc1 +Cc1cnc(CCNC(=O)CCc2nc(-c3cccnc3)no2)s1 +O=c1n(Cc2cc(F)ccc2F)nc2nc(N3CCCC3)ccn12 +O=C(Nc1nc(-c2ccco2)n[nH]1)c1ccc2c(c1)OCO2 +O=C1CC(C(=O)N2CCc3cc(F)ccc3C2)CN1Cc1ccco1 +Cc1nc(-c2nnn(-c3ccccc3)c2C)sc1C(=O)NC(C)C +O=C(NCCn1nc2ccccn2c1=O)c1ccc[nH]c1=O +O=C(CCc1ccsc1)N1CCCCC1CN1CCOCC1 +CSc1ccc(NC(=O)N2CCC3(CC2)OCCO3)cc1 +CCc1nc2c(N3CCC4(CCCN(C(C)C)C4=O)C3)ncnc2o1 +CC(CNC(=O)c1cccc2ncccc12)N1CCOCC1 +Cc1cc(C(=O)Nc2cc(C)on2)c2c(C)noc2n1 +Cc1cccc2nc(CSc3nc4ccsc4c(=O)n3C)cn12 +CC1COCC(C)N1C(=O)c1ccc2c(c1)NC(=O)CO2 +CCOc1ccc(C(=O)NCC(=O)N2CCOCC2CC(C)C)cc1 +O=S(=O)(c1ccccc1)N1CCC(c2ccsc2)CC1 +CC(C)c1ccc(C(=O)Nc2cccc(-n3cnnn3)c2)cc1 +CS(=O)(=O)N1CCC(NC(=O)c2cccnc2)CC1 +NC(=O)c1ccc(NC(=O)CCC(=O)c2ccc3ccccc3c2)cc1 +COc1ncnc2c1CN(Cc1nc(C)c(C)o1)CC2 +CCOCC1CCN(C(=O)NC2CCCCC2C(=O)NC)C1 +COC1CCN(C(C(=O)N2CCCCC2)c2ccccc2)CC1 +Cc1ccccc1NCCC(=O)Nc1c2c(nn1C)CCC2 +COc1ccc(Cl)cc1C1CCCc2nc(N)nn21 +Cc1nnc(SC(C)C(=O)NCCc2ccc(F)cc2)s1 +COCc1ccc(CNC(=O)CN2CC(C)OC(C)C2)cc1 +CC(C)C(O)C1(CNC(=O)c2cccnc2SC(F)F)CC1 +CC(O)c1cccc(OCC(=O)NC(C)(C)C)c1 +Cc1cccc(C(=O)NCc2nc(-c3cccc(C)c3)no2)c1 +Cc1ccc(C(=O)NC(C)C(=O)NC(C)(C)C)cc1F +O=C(c1cc[nH]n1)N1CCCC1Cc1cccc(F)c1 +Cn1c(=O)[nH]c(=O)c2c(-c3ccc4ccccc4c3)ccnc21 +FC(F)(F)CN(Cc1ccn(-c2ccccc2)n1)CC1CC1 +COc1ccc2c(c1)OCC(CNC(=O)CCN1CCCCC1=O)C2 +Cc1cccc(CN(C(=O)CN2CCCCC2=O)C2CC2)c1 +CC(=O)N1CCCC(C(=O)NCCc2cc(Cl)cc(Cl)c2)C1 +Cc1cc(C(=O)NCC(=O)NCCc2ccc(Cl)cc2)nn1C +CC(C)(O)CNC(=O)Nc1ccc(Oc2cccnc2)nc1 +Oc1cccc(-c2nc3c4cnn(-c5ccc(F)cc5)c4ncn3n2)c1 +Cc1nccn1-c1ccc(C(C)NC(=O)NCCC(=O)N(C)C)cc1 +Cc1ncc(CN(C)C(=O)NCCOc2ccc(Cl)cc2)s1 +CCOc1cc(CNC(=O)Cc2ccc(C)s2)ccc1OC +CCc1nc(C)c(C(=O)N(CC(=O)OC)c2cccc(F)c2)s1 +CC1CN(S(=O)(=O)NCCc2ccccc2F)CC(C)O1 +C=CCN1CCN(C)C(=O)C12CCN(C(=O)c1ccncc1)C2 +Cc1nnc(NC(=O)c2cc(-c3ccc(C)c(C)c3O)n[nH]2)s1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)OCC1CCCCO1 +Cc1c(Cl)cccc1N1CCC(C(=O)NC2CC2)C1=O +Cc1csc(N2CCCN(CC3=Cc4ccccc4OC3)CC2)n1 +Cc1nn(C)c(C)c1-c1cc(-c2nn3c(C(C)C)nnc3s2)[nH]n1 +NC(=O)C1CCN(C(=O)c2cccc3ncccc23)c2ccccc21 +CSc1ccc(C)c(C(=O)NC(C)(C)c2nc(C)c(C)s2)c1 +COc1ccccc1C(C#N)CC(=O)Nc1c(C)cccc1C +CC(=O)N1CCN(c2nnnn2-c2ccccc2)CC1 +CNC(=O)C(C)NC(=O)N1CCN(c2nccs2)CC1 +O=C(c1ccccc1-c1ccccc1)N1CCOCC(O)C1 +CNS(=O)(=O)c1cccc(CNc2cn[nH]c(=O)c2Cl)c1 +NC(=O)C(Cc1ccccc1)NC(=O)c1cc(=O)c2ccccc2o1 +CC(CNC(=O)C1(c2ccc(Cl)cc2)CC1)CC1(C)OCCO1 +Cn1nnnc1SCC1NCCc2c(F)cccc21 +O=C(NCc1ccc(OCC2CC2)cc1)c1cnn2ncccc12 +O=C(CSc1nnnn1C1CCCC1)c1ccc2c(c1)OCO2 +CSc1nnc(NC(=O)Nc2cccs2)s1 +Cc1cc(NC(=O)c2ccc3c(c2)NC(=O)C(C)S3)no1 +CC(C)CCN1C(=O)CCC2CN(C(=O)CCc3ccco3)CCC21 +CC(=O)c1cc(Cc2nc(C3CCOC3)no2)cs1 +O=C(NCC(F)(F)F)NC1C2CCC(C2)C1CO +Cc1cc(C)c(C#N)c(SCC(O)COCc2ccccc2)n1 +CCOCCCNC(=O)Nc1c(C)nc2ncnn2c1O +CCCCN1CCN(C(C)=O)c2ccccc2C1=O +Cc1cc(NC(=O)c2ccc(=O)n(Cc3cccc(F)c3)n2)on1 +Cc1csc(N(CC(F)(F)F)C(=O)c2ccc3c(c2)OCO3)n1 +O=C(c1ccccc1-n1cncn1)N1CCCC2(CCOC2)C1 +O=S1(=O)N=C2CCCCCN2C(c2ccncc2)N1 +COc1ccc(C2NC(=O)c3cccc(C)c3N2)cc1 +Cn1nccc1-c1nnc(NC(=O)c2ccccc2S(C)(=O)=O)o1 +Cc1ccc(F)cc1S(=O)(=O)NC1CCN(c2ccccc2)C1=O +CC(CNC(=O)c1cccc(-c2ccoc2)c1)Cn1cccn1 +Nc1ccc(-c2nnc(Cc3ccc(F)cc3)o2)cc1 +Cc1nnc2n1CCN(C(=O)c1[nH]c3ccccc3c1Cl)C2 +CCOc1ccc(F)c(C(=O)NC(C)c2nc3ccccc3[nH]2)c1F +O=S1(=O)CCCN1Cc1coc(-c2ccc(C(F)(F)F)cc2)n1 +Cc1ccsc1CNC(=O)CCNC(=O)c1ccoc1 +COc1cc(F)c(C(=O)N2CCCCC2CCO)cc1OC +NS(=O)(=O)c1cccc(NCc2ccccc2F)c1 +CN(C)S(=O)(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +O=C(Cc1csc(-c2nc[nH]n2)n1)NCCC1=CCCCC1 +Cc1ccc(-c2csc(CCN3CCOC3=O)n2)cc1 +O=C(Nc1cccnc1-n1cccn1)c1cc(-c2ccco2)[nH]n1 +O=C(Cn1c(-c2ccccn2)noc1=O)c1ccc2c(c1)CCO2 +CN(Cc1cnc2cnccn12)CC1CCCCO1 +COc1ccc(-n2ccnc2S(C)(=O)=O)cc1 +O=C1CCC2C(CCN2C(=O)c2ccco2)N1CC1CC1 +Cn1cc(NC(=O)c2cc3ccccc3c(=O)[nH]2)cn1 +CCCCN(C(=O)c1cccc(N2CCOC2=O)c1)C(C)CC +COCCNC(=O)CN1C(=O)C(C(C)C)Oc2ccccc21 +O=C(NCCc1ccc(F)cc1)C1CCN(C(=O)C2CC2)CC1 +Cc1ccc(-c2cn3cccnc3n2)cc1NC(=O)c1ccccc1F +Cc1ccc(S(=O)(=O)c2noc(C(N)=O)c2N)c(C)c1 +COc1ccc(C)cc1N1CC(C(=O)N2CCCC(O)C2)CC1=O +Cc1cc(C(N)c2nccs2)c2ccccc2n1 +COc1ccccc1C(=O)Nc1cccc(C(=O)N2CCCCC2)c1 +CS(=O)(=O)N1CCN2C(=O)N(C3CCCCC3)CC2C1 +O=C(c1cnccn1)N1CCOC2C(OCc3ccccn3)CCC21 +CC(C)OCc1ccc(CNC(=O)CC(F)(F)F)cc1 +Cc1cc(C)nc(SCc2ccc(C(=O)Nc3cnn(C)c3)o2)n1 +COCN1C(=O)C2(CCCCC2)N(C)c2ccc(N)cc21 +COC(=O)c1ccoc1CN1CCc2cc(Br)ccc21 +CC1(C)C(=O)NCCN1C(=O)c1ccc(Cc2ccccc2)cc1 +CNC(=O)c1ccc(CN(C)c2ncnc3cccc(F)c23)cc1 +Cc1ccnc(NC(=O)c2cnc(C3CCCO3)nc2N)c1 +CN(CC(=O)NC1CC1)C(=O)CSc1ccc(F)cc1 +CC(C(=O)N(C)C)S(=O)(=O)c1ccc(Cl)cc1 +CC(C)C(=O)Nc1ccc(-c2nc3ncccc3o2)cc1 +Cn1cc(C(=O)Nc2cccc(C(F)(F)F)c2)nn1 +CCc1nc(C)cn1C(=O)Nc1cccc2ccccc12 +Cn1cc(NCC(C)(C)NC(=O)OC(C)(C)C)cn1 +COCCN1CCN(c2oc(-c3ccco3)nc2C#N)CC1 +O=C(Cn1ccc(=O)[nH]c1=O)OCCc1cccs1 +COC1CCN(C(=O)NC2CCC(O)CC2)CC1 +CN(c1ccccc1)S(=O)(=O)c1ccc(F)c(F)c1F +Cc1ccc(S(=O)(=O)Nc2cc(N)ccc2C)cc1 +COc1ccc(C(=O)c2c[nH]c3ccc(OC)cc3c2=O)cc1 +Cc1cc(OCC(=O)Nc2cccc(C(=O)N(C)C)n2)ccc1Cl +CCOc1cc(CNC(=O)c2ccc(=O)n(CC)n2)ccc1OC +COCCNC(=O)NC1CCN(c2cc(C)cc(C)c2)C1=O +C=CCNS(=O)(=O)c1ccc2cc(OC)ccc2c1 +CCn1c(SCc2cccnc2)nnc1-c1ccccc1 +Cc1noc(C)c1CC(=O)Nc1onc2c1CCCC2 +Cc1cc(C)n2cc(CNc3ccc(C#N)cc3)nc2n1 +CCC1CNc2ccc(Br)cc2N1CCOC +CCCN(CCC)C(=O)Nc1cc(OC)ccc1OC +CCOc1ccc(Cl)c2sc(NCCOC)nc12 +Cc1nc2c3ccccc3nc(SCCCC#N)n2n1 +COc1ccnc(NC(=O)c2c(C)nn(C)c2C)c1 +O=C(NCCc1ccco1)c1cccc(OC(F)F)c1 +CSc1nc(N)n(C(=O)c2ccccc2Cl)n1 +CCC(NC(=O)COc1ccccc1)c1ccccc1 +CCCCCC(C)NC(=O)c1cc(C(N)=O)cs1 +CC(=O)NCC1CCCN(C(=O)C2CC(=O)N(CC(F)(F)F)C2)C1 +O=C(c1ccc2c(c1)OCCO2)N1CC(c2ccccn2)C1 +CC(C(=O)Nc1ccc(F)cc1)n1ncc2ccccc2c1=O +O=C(Nc1ccc2cn[nH]c2c1)c1cnc2ccccc2n1 +COc1ccc2c(c1)c(C(=O)N(C)C)c(C)n2C1CCCCC1 +COc1cccc(NC(=O)C2CN(C(C)=O)c3ccccc3O2)c1 +COc1cccc2c(=O)c(C(=O)NCc3cccnc3)c[nH]c12 +CCN(CCO)C(=O)NC1CCCc2c1cnn2Cc1ccccc1 +Cc1ncc(CNC(=O)Nc2cccc(Cl)c2Cl)s1 +Cc1ccc(C(=O)NC2CCN(c3ncccn3)CC2)cn1 +Cc1c(-c2nc(CC(C)C)no2)cnn1-c1ccncc1 +CC(C)n1cc(NCc2cnc(-c3ccccn3)s2)cn1 +CCc1c(C)nc2cc(C3CCOCC3)nn2c1NC(C)COC +O=C(Nc1cnc2ccccc2c1)c1cccc2nscc12 +O=C(c1csc(Cc2ccccc2)n1)N1Cc2ccccc2C1 +Cn1c(N)c(C(=O)CSc2ccccc2Cl)c(=O)n(C)c1=O +COCCNC(=O)NCc1ccc(OC2CCCCC2)nc1 +Cc1occc1C(=O)NCCNC(=O)c1ccccc1O +Cc1cc(C(=O)N2CC3CCCN(C(=O)c4cc(C)n[nH]4)C3C2)[nH]n1 +Cc1ccc(NC(=O)NCCn2cnc(C)c(C)c2=O)cc1F +O=C(Nc1ccnn1Cc1ccc(Cl)c(F)c1)c1cc[nH]n1 +CCOc1cccc(-c2nc(C)c(C(=O)OC)s2)c1 +COc1ccc(-c2cc3ncc(N)cn3n2)c(OC)c1 +CCOC(=O)NC(N1CCCCC1)(C(F)(F)F)C(F)(F)F +COCCOc1ccc(NC(=O)c2cccc(-c3ccoc3)c2)cn1 +COCC1(C(=O)N2CCC(C(O)c3cccs3)CC2)CCC1 +CCCn1ccc(NCc2c(OC)cccc2OC)n1 +COC(=O)C1CN(Cc2ccc(F)c(C)c2)CCO1 +COCc1nn2c(-c3ccc(OC)cc3)nnc2s1 +CS(=O)(=O)N(CC(=O)NC1CCCCC1)c1ccccc1 +COc1ccc2oc(=O)c(C(=O)N3CC(C)OC(C)C3)cc2c1 +CCOc1cc(C#N)ccc1OCC(=O)N(CC)c1ccccc1 +O=C(Cc1ccccc1F)N(Cc1ccccn1)C1CC1 +O=C(Cn1cncn1)NC1CCc2cc(F)ccc21 +CC1CCN(C(=O)CC2CSc3nc(C(C)C)cc(=O)n32)CC1 +COc1ccc(CC(=O)Nc2nnc(-c3ccnn3C(C)C)o2)cc1 +CC(C(=O)N1CCC(OCc2ccccc2F)CC1)c1cccnc1 +O=C(Cn1sc2ccccc2c1=O)N(Cc1ccsc1)C1CC1 +O=C(NC1CC1)c1ncc(-c2cccc(C(F)(F)F)c2)o1 +CC1CCN(C(=O)CSc2nnnn2C)CC1 +Cc1ncc(CNC(=O)c2ccn(-c3cccc(Cl)c3)n2)s1 +CCn1cc(CNc2nnc(Cc3cccc(F)c3)o2)cn1 +N#Cc1ccc(-c2noc(-c3cc(C#N)c[nH]3)n2)nc1 +Cc1nc(C)c(C(=O)NC(C)c2ccccc2C)s1 +Cc1c(-c2nnc(C(=O)NCc3cccnc3)o2)oc2c(C)cccc12 +CC(=O)N1CCC(C(=O)N2CCCC(C)(C)c3ccccc32)CC1 +CNC(=O)CSc1nnnn1-c1ccc(C)cc1C +O=C(NCCNc1cc(N2CCOCC2)ncn1)c1cccs1 +Cc1cc(-c2nnn(CC(=O)N(C)CCC#N)n2)ccc1F +CCc1noc(CC)c1CC(=O)Nc1ccc(-c2nnc(C)o2)cc1 +Cc1ccc(O)c(C(=O)NCCCN2CCCCCC2=O)c1 +C1CCC(CN2CCn3c(nnc3C3CC3)C2)CC1 +CC(CNC(=O)N(C)Cc1ccc(F)c(F)c1)Cn1cccn1 +NC(=O)C1(CNC(=O)CCOc2ccccc2F)CCOCC1 +Cc1nc(C)c(CC(=O)N(C)C(C)c2ccccn2)s1 +N#Cc1ccc(C(=O)C(C#N)c2ccc(C(F)(F)F)cn2)cc1 +Cc1cccc(Cl)c1NC(=O)Cn1nnnc1C(C)C +Cc1ccc(NC(=O)CSc2nc(N)cc(=O)[nH]2)cc1Cl +CCOc1ccc2ncc(C#N)c(N3CCC4(CC3)OCCO4)c2c1 +O=C(Cn1ccc2ccccc21)NC1CCOCC1 +CCCOc1ccccc1NC(=O)N1CC2CCC1C2 +COC(=O)C1CCCN1Cc1cn2ccsc2n1 +CC(CO)C(C)NC(=O)NCc1cccc(NC(=O)C2CCC2)c1 +CCOC(=O)c1nn(-c2nccs2)c2ncccc12 +COc1ncccc1NC(=O)N1CCC(C(N)=O)CC1 +CC(CC(=O)N1CCC(C(N)=O)CC1)c1ccccc1 +COCCOCC(=O)N(C)c1cccc2ccccc12 +COC(=O)c1cc(S(=O)(=O)Nc2ccc(C)c(Cl)c2)cn1C +O=C1CCCN1Cc1ccc(NCc2cccnc2)cc1 +COc1ccc(C(C)=O)cc1CC(=O)NC1CCCc2ccccc21 +CN(CC(=O)NC1CCCCC1)S(=O)(=O)c1ccc(Cl)cc1 +CCOc1ccc2[nH]c3c(N4CC(C)OC(C)C4)ncnc3c2c1 +Cc1ccc2cc(C(=O)N=c3[nH]ncn3C)[nH]c2c1 +CC(C)Cc1nc2c(N)cccc2n1CC(=O)OC(C)C +CCN(Cc1cccc(Cl)c1)C(=O)Cc1ccon1 +CSc1nc2ccccc2c(NCc2ccncc2)c1C#N +C#CC(O)(Cc1ccc(OC)cc1)c1ccc(OC)cc1 +O=C(Cn1nnnc1CN1CCc2ccccc2C1)N1CCOCC1 +Cc1nc(N(C)CC2CC(=O)N(C3CCCC3)C2)c2sccc2n1 +O=C(Nc1cccnc1)Nc1nnc(C2CCCCC2)s1 +CN(C)C(=O)c1cccc(NC(=O)Nc2ccccc2)c1 +Cc1nc(C)c(C(=O)NCC(C)(C)c2ccccc2)s1 +COc1ccc(NS(=O)(=O)N2CC(C)OC(C)C2)cc1 +Cc1cc(NC(=O)Cn2ccc(-c3ccc(C)s3)n2)n(C)n1 +CCOc1cccc(NCc2cn(C)nc2-c2cccnc2)n1 +COCCOc1ccc(NC(=O)c2cccc(OC)c2F)cn1 +CN(Cc1ccc(F)cc1)C(=O)COc1ccc(C#N)cc1Cl +CCCN1C(=O)C2CCC1CN(C(=O)Nc1ccc(C)cc1)C2 +COc1ccc(NC(=O)NCc2cccnc2)cc1OC(F)F +O=C(NCCCNc1ncccn1)Nc1ccccn1 +Cc1nnc(N2CCCC2CNC(=O)OC(C)(C)C)s1 +CCCCOC(=O)CN1CCCOc2ccc(N)cc21 +CCOC(=O)CN(Cc1ccccc1)C(=O)C(C)C +Cc1cc(Br)ccc1SCC(=O)NCC1CCCO1 +Cn1cnc(CNC(=O)c2ccccc2NC(=O)c2ccsc2)n1 +CC(=O)NC(CC(=O)N1CCCC(C(F)(F)F)C1)c1cccs1 +O=C(NCCn1nc2ccccn2c1=O)c1ccoc1 +O=C(NC1CC1)C1CCCN(C(=O)c2cc3ccccc3[nH]2)C1 +CC(NC(=O)NCc1cc[nH]n1)c1ccc(OC(F)(F)F)cc1 +COc1ccc(C(=O)OCc2cc(-c3cccs3)on2)cn1 +O=C(Nn1cnc2ccccc2c1=O)c1ccc(C(F)(F)F)cc1 +Cc1ccc(C(=O)N2CCn3c(nnc3C(F)(F)F)C2)c(O)c1 +CCCCc1nc(CN2CCN(CC(C)O)CC2)cs1 +Cc1nnc(SCc2cc(=O)oc3cc4c(cc23)CCC4)n1N +Cc1n[nH]c(C)c1CCc1ccc(S(C)(=O)=O)cc1 +CN(C)C(=O)C1CCCN(C(=O)c2cc(Cl)c[nH]2)C1 +Nc1ccnc(CN(CC2CC2)CC(F)(F)F)n1 +Cc1ccn2c(=NC(=O)c3cc4ccccc4oc3=O)[nH]nc2c1 +O=C(c1ccc(Cl)cc1)N(Cc1ccsc1)C1CC1 +COc1ccc2c(c1)N(C(=O)C1CC=CCC1)CCO2 +N#Cc1ccc(-c2nnc(SCC(N)=O)o2)cc1 +CC(Oc1ccccc1)C(=O)Nc1ccccc1-c1nnnn1C1CC1 +CCOCCNC(=O)c1ccc(-c2cccs2)[nH]c1=O +c1ccn2c(-c3ccc4c(c3)OCCO4)nnc2c1 +Cc1ncsc1CCOC(=O)c1ccc(N2CCCC2=O)cc1 +CC(CCC(=O)Nc1cccnc1)CC(=O)Nc1cccnc1 +Cc1ccc(CC(=O)N2CCC(NS(C)(=O)=O)CC2)s1 +Cc1ccc(S(C)(=O)=O)cc1NCc1nc(-c2ccsc2)no1 +CCC(C)NS(=O)(=O)c1ccc(OC)c(C)c1C +Cc1cc(C)c(S(=O)(=O)Nn2cnnc2)c(C)c1 +COc1ccc(C(O)CCNc2ccccc2OC)cc1 +COC(=O)C1=C(C)C(C(=O)COc2ccc(F)c(F)c2)=NC1C +Cc1cc(O)cc(C)c1NC(=O)c1ccc(Br)cc1 +COCCCN(C)C(=O)Nc1c(C)cc(Br)cc1OC +CC(C)Cn1nccc1NC(=O)Cn1ccccc1=O +Cc1cc(NC(=O)C2CC2)n(-c2nc(-c3cccs3)cs2)n1 +Cc1noc(C)c1CN(C)C(=O)c1ccnc(-n2cncn2)c1 +NC(=O)CSc1nccn1-c1c(F)cccc1F +Cc1noc(CCC(=O)OCC2CSc3ccccc3O2)n1 +N#Cc1ccc(S(=O)(=O)NCc2nnc3ccccn23)cc1 +Fc1cc(Br)c2c(c1)C(CC1CC1)NCC2 +Cc1ccc(C(=O)C(C)n2nnc3ccccc32)cc1 +Cc1ccc2c(c1)CC(=O)N2CC(=O)c1ccc(F)cc1 +C#CCNC(=O)N1CCN(c2ccccc2C)CC1 +Cc1cc(=O)c(O)c(CN2CCOCC2)n1CC(C)O +COc1cc(NC(=O)CCC(C)C)cc(OC)c1 +CCOCCNC(=O)N1CCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1ccc(-c2nc(C#N)c(S(=O)(=O)n3ncnc3N)o2)cc1 +CCc1nc(CNc2ccc(S(C)(=O)=O)cc2C)no1 +CCOC(=O)C(O)c1nc2c(C)cccc2s1 +O=C(CCCS(=O)(=O)c1ccccc1)Nc1ccc(F)cc1 +C#CCN1C(=O)C(Cc2ccccc2F)Oc2ccc(O)cc21 +COc1ccc(Cl)cc1NC(=O)Cc1cn2ccccc2n1 +O=C(NCc1ccc(COCC(F)(F)F)cc1)c1n[nH]c(=O)[nH]1 +Cc1csc(C2CCCN(C(=O)C(C)n3ccnc3)C2)n1 +O=C(Cc1ccc2c(c1)OCO2)Nc1nccs1 +CCOc1ccccc1C(=O)N1CCCC1C(=O)N(C)CCC#N +O=S(=O)(CCc1ccccn1)NCc1cn[nH]c1 +CN(C(=O)c1ccc(S(=O)(=O)C(F)F)cc1)c1ccccn1 +CNC(=O)c1ccc(OC2CCCN(C(=O)OC(C)(C)C)C2)cc1 +Cc1cc(C)n(CC(=O)NCCC(O)c2ccco2)n1 +CN(C)S(=O)(=O)c1ccc(=O)n(CC(=O)c2ccccc2F)c1 +CCCn1c(SCC(=O)OC)nc2ccccc2c1=O +Cc1cccc(C(=O)CN(CC(F)(F)F)C2CC2)c1 +CCOC(=O)C(C#N)c1nc2ccccc2nc1N(CC)CC +COCc1cc(=O)[nH]c2cc(NC(=O)CCc3ccccc3)ccc12 +Cc1nn(C)c(=O)c(C(=O)N2CCCc3cc(Cl)ccc32)c1C +COc1cc(C(=O)N(C)C(C)C)ccc1OCC(N)=O +O=C1NCCN1C1CCN(c2ncnc3ccsc23)CC1 +O=C(Nc1cc[nH]n1)c1ccc(SCc2cn3ccccc3n2)cc1 +NC(=O)C(c1ccccc1)N1CCN(c2cccc(Cl)c2)CC1 +CC(OC(=O)c1ccc(OCC(F)F)nc1)C(F)(F)F +Cc1cc2nc(N3CCN(CC(C)O)CC3)c3ccccc3n2n1 +Cc1nnc(CN2CCN(c3cccc(C)c3C)CC2)o1 +O=C1OCCC1Sc1nnc(N2CCCC2)n1CC1CCCO1 +CC(NC(=O)CCc1nc(-c2nc[nH]n2)no1)c1ccc(F)cc1F +O=C(NCc1ccc(OC(F)(F)F)cc1)c1ccc2[nH]ccc2n1 +Cc1cccc2nc(C(=O)N(Cc3ccccc3)c3ccccn3)cn12 +COCCCNC(=O)CN1CCn2nc(-c3ccccc3)cc2C1=O +CCOC(=O)c1sc(=NC(=O)CCc2cc(OC)no2)[nH]c1C +Cc1nn2cc(C(=O)NCCC(=O)N3CCCC3)nc2s1 +COCCCN1Cc2cc(Br)ccc2OCC1=O +COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CC(C)(C)C +CCOc1cc(CCNS(=O)(=O)c2ccc(N)cc2)ccc1O +Cc1cccc(NC(=O)c2cnc(N(C)C)nc2N)n1 +Cc1nnc(Sc2ncnc3scc(-c4ccccc4)c23)n1C +CC(C)C(=O)NCCNC(=O)c1ccc(-n2cccn2)cc1 +O=C(NCCNC(=O)C1(c2cccc(Cl)c2)CC1)C1CC1 +CC(C)N(C(=O)c1cccc(N(C)C)c1)C1CCOCC1 +Cc1c(CO)nnn1-c1cccc2c(O)cccc12 +O=C(NC1CCN(c2cccc(F)c2)CC1)C1CCCO1 +COC(=O)c1ccccc1NCC(=O)NCc1ccc2c(c1)OCO2 +O=C(CNC(=O)c1ccc(-n2ccnn2)cc1)Nc1ccc(F)cc1 +CCC=CCOC(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C +COc1cccc(CS(=O)(=O)c2ccc(C)c(C)c2)c1 +O=C(NCc1ccnc(OC2CCC2)c1)N1CCC2(CCCC2)C1 +COc1ccc(NC(=O)c2coc(=O)c3ccccc23)cc1OC +Cc1cnc(C)c(-c2cccc(-c3ccn(CCn4cccn4)n3)c2)n1 +CCC(CC)C(=O)N1CCCC2(COCCN(c3ncccn3)C2)C1 +CC1CCCCC1NC(=O)CSc1nnc(CO)n1C1CC1 +CSc1cccc(NC(=O)c2cc3c([nH]c2=O)CCCC3)c1 +C=CCN(Cc1cccc(C#N)c1)C(=O)NCc1sc(C)nc1C +CC(CNC(=O)Cc1cccc(OCC#N)c1)c1ccsc1 +CCCC(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1 +N#Cc1cccc(NC(=O)N2CCC(c3nnc4ccccn34)CC2)c1 +CCCn1nc(C(=O)N(C2CC2)C2CCc3ccccc32)ccc1=O +COC(=O)c1cc(Br)ccc1OCc1ncnn1C +Nc1cc(S(=O)(=O)N2CCc3ccccc3C2)ccc1Cl +Nc1ccc(F)c2c(NCCCO)ncc(Br)c12 +O=C(COc1ccc(Br)cc1)OCCN1CCCC1=O +CC(NC(=O)c1ccccc1CN1CCOCC1)c1ccccn1 +O=C(c1ccoc1)N1CCN(c2cccc(Cl)c2)CC1 +O=C(NCCc1ccccc1)c1nn2ccccc2c1Cl +Cc1nnc2n1C(C)CN(C(=O)c1cc(C(C)C)no1)C2 +COc1cc(NCc2cccc(Cl)c2)ccc1N1CCCC1=O +CN(Cc1nc(-c2cccnc2)no1)C(=O)c1cc(C2CC2)n[nH]1 +COCCC1CCCCN1C(=O)c1ccc(CCC(C)(C)O)cc1 +Cc1nc(-c2ncccn2)sc1C(=O)OC1CCOC1=O +CCS(=O)(=O)N(C)C(C)Cc1ccc(Cl)cc1 +CN(Cc1nnc2n1CCC2)C(=O)C1CC(=O)N(CC2CC2)C1 +CC(C)(C)OC(=O)NCCNC(=O)NCC1CCCC1 +COc1ccc(CNC(=O)c2ccc(C(C)=O)s2)cn1 +C#CCN1CCN(C(=O)Cc2ccc(OC)cc2)CC1 +COc1ccc(SC(C)C(=O)Nc2ccn(C)n2)cc1 +O=C(NCC1CN2CCCCC2CO1)C1CCC(F)(F)CC1 +COc1cc(OC)c(C(=O)NCc2ccccc2F)cc1OC +CCNC(=O)CN(C)C(=O)c1cc(Cl)c2c(c1)OCO2 +CCN(C(=O)CCSc1ccc2c(c1)OCCO2)c1cccnc1 +CC(=O)Nc1cccc(C(C)NC(=O)CCc2ccc3[nH]ccc3c2)c1 +O=C1c2cc(Cl)c(Cl)cc2OCCC1(CO)CO +COc1cc(C(=O)N(C)C(C)c2ccco2)cc(OC)c1C +O=c1[nH]cccc1C1NCCc2cc(F)cc(Cl)c21 +Cn1nc(-c2ccccc2)c(-c2nc3ccccc3[nH]2)c1N +Cc1ccccc1C(C)NC(=O)c1ccc(S(C)=O)cc1 +CCn1nnc2cc(C(=O)OCCCc3ccncc3)ccc21 +Cc1cc(Br)ccc1C(=O)Nc1ccc(N(C)C)cn1 +O=C(Nc1cccc(-n2cnnn2)c1)C1CC2C=CC1C2 +CN(CC1(O)CCCC1)C(=O)NCc1ccnc(OC(C)(C)C)c1 +O=C(Cc1c[nH]c2ccccc12)Nc1ccn(Cc2ccc(F)cc2)n1 +CC(O)c1nc2cc(N)ccc2n1Cc1cccc(C#N)c1 +O=S(=O)(c1ccc(NCc2ccccc2)nc1)N1CCCC1 +CC1CN(c2ccccc2NC(=O)c2csnn2)CC(C)O1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cnn(-c2ccccc2)n1 +CN(C)C(=O)Cc1ccc(NC(=O)c2ccc(C#N)cc2)cc1 +CCOc1ccc2nc(NC(=O)c3ccn(C)c3)sc2c1 +CN(C)c1ccc(C(=O)Nc2nccs2)cc1F +CCN(CC1CCOC1)C(=O)c1ccc(C)c(N)c1 +Cc1cccc(CNC(=O)CNc2ccc(C#N)cc2)c1 +CCNC(=O)NCCCOC(C)c1ccccc1 +CC(=O)c1sc(N(C)Cc2csc(C)n2)nc1C +CCC(=O)Nc1cccc(NC(=O)Nc2ccc(OC)cc2)c1 +CCc1ccc(S(=O)(=O)Oc2ccc3c(c2)CCC(=O)N3)cc1 +Cc1cc(-c2nc3c4c5c(sc4ncn3n2)CCC5)nn1C +Cc1nn(-c2ccccc2Br)cc1N +CCOCCNC(=O)Nc1ccc(C(=O)NC2CCCCC2)cc1 +O=C(NCc1ccccc1Cl)c1n[nH]c(=O)c2ccccc12 +COc1ccc(-c2cc(C(=O)OC(C)C)no2)c(OC)c1OC +Cc1cc(C)cc(NC(=O)CC(NC(N)=O)c2ccccc2Cl)c1 +Cc1cc(C)cc(NC(=O)CC2NC(=O)c3ccccc3NC2=O)c1 +Cc1noc(C(C)C)c1C(=O)NCCNC(=O)c1cccn1C +Cc1cc(C)n(-c2cc(Oc3cccc4cccnc34)nc(C)n2)n1 +CCOC(=O)Cc1nc2ccccc2n(CC2CC2)c1=O +OCC(Cc1ccc2c(c1)OCO2)c1ccccc1F +CNC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +N#Cc1ccc(N2CCC(N3CCNC3=O)CC2)c(F)c1 +CCOC(=O)c1sc(N(C(=O)c2cccc(F)c2)C2CC2)nc1C +CC(NC(=O)NCc1nc2ccccc2s1)C1CCCO1 +CCCS(=O)(=O)NCc1ccc(N2CCCC2=O)cc1 +CCOC(=O)Nc1cccc(C(=O)Nc2ccc(F)cc2)c1 +CC(C)CCOC1CCN(C(=O)c2scnc2C2CC2)C1 +Cc1nn(-c2ccccc2Br)nc1N +O=C(Nc1cnn(C2CCOCC2)c1)c1cc(-c2ccco2)on1 +O=C1Nc2cc(F)ccc2C1Nc1ccccc1Cl +O=C(c1ccsc1)N1CC2COCC2(COc2ncccc2F)C1 +Cn1ncc2c(N3CCCCC3)nc(C(=O)N3CCOCC3)nc21 +Cn1nccc1C(=O)N1CC2COCC2(Cc2nnc(C3CC3)o2)C1 +CCCNC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1 +Cc1c(C(=O)NCC(=O)Nc2cccc(F)c2)oc2ccccc12 +CNC(=O)Cn1ccc2ccc(NC(=O)N(C)CCC#N)cc21 +COCCc1ncc(OC)c(NS(=O)(=O)c2ccc(C)cc2)n1 +Cc1cc(C)n(-c2ccc(C(=O)NCC(F)(F)F)nn2)n1 +CC(C)CCn1c(SCCC#N)nc2ccccc2c1=O +CCCCN(C)S(=O)(=O)N1CCOc2ccc(F)cc21 +Cc1nc2c(cc(OCC(=O)N3CCC(O)C3)c3ccsc32)s1 +C#CC(C)OC(=O)c1ccc(-n2cnc3ccccc32)nc1 +Cc1cc2ccccc2n1CCCNC(=O)c1cccn(C)c1=O +CC(=O)c1ccc(NC(=O)C2CC(=O)N(C3CCOCC3)C2)cc1 +Cc1nc(CNc2ccc(C(=O)NC(C)CO)cc2)no1 +COc1cccc(CC(=O)Nc2ncccc2OCc2ccncc2)c1 +Nc1ncnc(SCC(=O)NCc2cccnc2)n1 +O=c1cnc2ccccc2n1Cc1nccn1C1CC1 +Cc1ccc(C(=O)N2CCCCC2CNC(N)=O)s1 +COc1ccccc1-n1nnc(CO)c1C1CCCCC1 +O=C(NCCc1ccc(Cl)cc1Cl)c1cncc2cnccc12 +COC(=O)C1CN(Cc2cnc(C3CCC3)s2)CCO1 +Cc1cccc(NC(=O)C(C)Oc2cccc3ccc(=O)[nH]c23)c1C +CCc1nnc(NC(=O)c2c[nH]c3ccc(OC)cc3c2=O)s1 +CCCn1c(=NC(=O)c2ccc3nnc(C)n3c2)[nH]c2ccccc21 +Cc1cc(C(=O)N2CCC3C(CCC(=O)N3CCCO)C2)ccc1F +O=C1Cc2cc(NC(=O)C34CC5CC(CC(C5)C3)C4)ccc2N1 +Cc1nsc(N2CCN(CC3=CCCOC3)CC2)n1 +CCc1noc(C)c1C(=O)NC1CCCCCC1 +Cc1nccn1-c1ncccc1NC(=O)C1CC(=O)N(C)C1 +CCOc1c(Cl)cccc1NC(=O)N(C)C(C)CC#N +COc1ccc(NC(=O)NCCN2CCOCC2)cc1F +CN1C(=O)COc2ccc(C(=O)Cn3cnc4ccccc4c3=O)cc21 +CC(Cc1cccs1)NC(=O)NCCN1CCOCC1 +O=C1Cc2cc(S(=O)(=O)NCc3cccs3)cc3c2N1CCC3 +O=C(Cc1ccccc1Cl)Oc1ccc(-n2cnnn2)cc1 +NC(=O)c1sc2nc3c(c(-c4cccs4)c2c1N)CCC3 +CC(C)(C)c1csc(C2CCCCN2C(=O)Cc2cccnc2)n1 +Cc1noc(CNc2ncnc3sc(C)c(C)c23)n1 +CSc1ncc(C(=O)Nc2cccc(O)c2)n1-c1ccccc1 +CC(Cn1nc(-c2cccs2)ccc1=O)C(=O)NCC(F)(F)F +COC(=O)C1CCC(=O)N1c1ccc(Br)cc1 +CCN(CC(C)C#N)C(=O)c1cccc2[nH]ncc12 +CC(C)(C)C(=O)NCc1ccc(Cn2ccccc2=O)cc1 +N#Cc1ccc(-c2noc(C=CC3CCOCC3)n2)nc1 +Cc1nn2c(-c3ccc(F)cc3)ccnc2c1Cl +COCCNC(=O)N1CCN(C(C)C(=O)NC2CCCC2)CC1 +CC(=O)NCCC(=O)NC1CCCOc2c1ccc(Cl)c2Cl +O=C(Nc1ccc(N2CCOCC2)nc1)c1cnc2ccccc2n1 +CCOC(=O)C1=C(C)N(CC)C(=O)NC1c1ccc(O)c(OCC)c1 +Nc1ccc2c(c1)C(=O)N(c1ccc(F)c(Cl)c1)C2 +CN(C)C(=O)CN(C)C(=O)c1csc(-c2cccc(Cl)c2)n1 +COCCC1NCCc2c(F)ccc(Br)c21 +CCOc1ccc(-c2cn(-c3cc(N)ccc3C)nn2)cc1 +COc1cccc2c1CCCCN2C(=O)c1cscn1 +Cc1ccc(C(=O)NCC(F)(F)F)cc1NC(=O)c1ccccc1 +Nc1ccc(Cl)c(NC(=O)C2CCOCC2)c1 +O=C(Cc1ccc(F)c(F)c1)N1CCC(CN2CCOCC2)C1 +CCN1CC(C(=O)N2CCc3cc(F)ccc3C2)CC1=O +Cc1ccccc1OCCSc1nnc(-c2ccncc2)o1 +CC(=O)NCCNC(=O)COc1ccccc1N +N#Cc1nccnc1Sc1nnc(-c2cc3ccccc3o2)o1 +COc1ccc(SCC(=O)N(Cc2cccs2)C2CC2)cc1 +CCNc1ccc(C(=O)N(CCO)C(C)C)cc1 +CNC(=O)c1cccc(OC(=O)c2cnc(C3CCCO3)s2)c1 +CC(C)n1cnc2c1C(C(=O)N1CCCC1)N(S(C)(=O)=O)CC2 +Cc1ccc(N2CCCC(NC(=O)Nc3cnccc3C)C2=O)cc1 +CNC(=O)c1ccc(NC(=O)c2cc(F)ccc2F)cc1 +Cc1cc2c(cc1C(=O)Nc1ccccc1F)OCCCO2 +CC(=O)Nc1cccc(S(=O)(=O)NCC2CCOC2)c1 +Cc1nc2cc(NC(=O)c3cnn(C)c3-n3cccc3)ccc2o1 +COc1cc2cc(CNc3ccc(C)cc3C)c(=O)[nH]c2cc1OC +CCOc1ccc2ccccc2c1C(=O)N1CC(c2nc(C)no2)C1 +CCC(=O)N1CC(=O)N(c2ccccc2C#N)CC1Cc1ccccc1 +Cc1nc(Cc2ccc3c(c2)OCO3)nc(C)c1N +Cc1cccc(NCc2cc(C(N)=O)ccc2F)c1 +COC(=O)c1ccc(OC)c(OC)c1C(=O)OC +CCC(Cc1ccc(C)cc1)NC(=O)N1CCCC1C(=O)NC +Cc1cccc(C)c1OCCCNC(=O)N1CCC(C(N)=O)CC1 +CCC(C)Oc1cccc(-c2cc(CO)c(=O)n(C)n2)c1 +CNC(=O)c1ccc(S(=O)(=O)N(C)Cc2cc(C)on2)cc1 +Cc1c(C#N)c(SCC(=O)NCc2ccco2)nc2c1CCC2 +CN(CC(=O)NCCc1ccc(O)cc1)c1cnccn1 +CC(NC(=O)Nc1cccc(Cl)c1)c1nc[nH]n1 +CNC(=O)C1CCCN1C(=O)c1ccc(F)cc1 +Cc1nc2ncnn2c(C)c1CCC(=O)NCCCO +COCCNc1nnc(SCc2nc(C)c3ccccc3n2)s1 +Cc1cc(NC(=O)c2sc(Cc3ccccc3)nc2C)ccn1 +COC(=O)c1ccccc1CNc1ccc(C)cc1 +CCSc1ncc2c(=O)n(CC(=O)N3CCCCC3)cnc2n1 +CC(C)c1cc(NC(=O)CCSc2ccccc2F)[nH]n1 +CC(C)(CO)NC(=O)c1ncc(Cl)c(Cl)c1Cl +C=CCNC(=O)Nc1nc(C)c(C(=O)OCC)s1 +CCS(=O)(=O)N1CCCCCC1c1cccc(F)c1 +CCN1CCc2nc(-n3nc(C)cc3N)nc(C)c2C1 +c1cncc(OCc2noc3c2CN(Cc2ccoc2)CC3)c1 +Cc1ccc(S(=O)(=O)Nn2nnc(-c3ccccc3)n2)cc1 +COCC(=O)N1CCCC(c2ccnc(Nc3cncnc3)n2)C1 +COc1cccc2c1OCC(C(=O)NCCCn1cncn1)C2 +CC(C)(C)c1nnnn1CC(=O)Nc1ccc(OC(F)(F)F)cc1 +Cc1ncc(C(C)NCCc2ccn(-c3ccc(F)cc3)n2)s1 +CC(=O)c1cnoc1-c1ccc(Br)cc1 +CN(CCNC(=O)c1ccccc1)c1ccccc1 +CCC(C)NC(=O)c1cccc(CNC(=O)NCc2ncn(C)n2)c1 +CC(C)c1cc(C(=O)N2CCN(C3CCCC3)C(=O)C2)no1 +CCC(C)n1ncc(C(=O)N2CCC(c3ccn[nH]3)CC2)c1C1CC1 +CC1CN(Cc2c(F)cccc2Cl)CC(C)O1 +O=C(CCCC(=O)c1ccc2c(c1)CCC2)NCc1ccco1 +CC(CC(=O)c1ccco1)NC(=O)c1ccc(-n2ccnn2)cc1 +COc1c(F)cc(NC(=O)N2CCc3cc(F)ccc3C2)cc1F +Nc1ccc(-c2nn3c(C4CC4)nnc3s2)c(Cl)c1 +Cc1ccc2nc(CCN3CCOC(C(F)(F)F)C3)[nH]c2c1C +COc1cc(NCc2ccccc2F)ccc1N1CCCC1=O +CCCc1nn2c(=O)cc(COC(=O)c3cccc(F)c3)nc2s1 +CC(C)S(=O)c1ccc(C(=O)NCCc2cccc(Cl)c2)cc1 +Cc1cc(Cl)ccc1NC(=O)c1cccnc1N1CCCC1 +COc1ccccc1C(=O)Nc1ccc(CNC(N)=O)cc1 +Cn1cc(C(=O)Nc2ccc(C(N)=O)c(Cl)c2)c(C(C)(C)C)n1 +Cc1ccc(-c2noc(CS(=O)(=O)c3nc(C)cs3)n2)cc1 +CCCC(=O)Nc1sc(C)c(CC)c1C(N)=O +COc1ccc(S(N)(=O)=O)cc1C(=O)N(C)CC1CC1 +Cc1ccc2nc(Cn3c(=O)oc4ccccc43)cn2c1 +COc1ccc(OC)c(C(=O)COC(=O)c2ccccc2)c1 +Cc1cc2ncn(CC(=O)N(C(C)C)C(C)C)c2cc1C +CCCNC(=O)c1cc(S(C)(=O)=O)c(Cl)cc1Cl +Cc1sc2ncnc(NCC3CCOCC3)c2c1C +CCC(=O)N1CCCN(C(=O)NC2CCCCC2C)CC1 +Fc1cccc(F)c1CN1CCOC(c2cccs2)C1 +CN(Cc1nc(-c2cc3ccccc3o2)no1)C(=O)OC(C)(C)C +CCC(CO)NC(=O)c1nc(S(C)(=O)=O)n2ccccc12 +COc1cccc(COCC(=O)N2CCCC(c3nncn3C)C2)c1 +O=C(CSc1ccccc1)Nc1cc(F)cc(F)c1 +CC(OC(=O)Cn1cnnn1)C(=O)c1c[nH]c2ccccc12 +Cc1occc1C(=O)NCC(=O)N(C)C(C)c1cccnc1 +Cn1ccc(NC(=O)Cn2cc(C(F)(F)F)cc(Cl)c2=O)n1 +CN1C(=O)Cc2cc(S(=O)(=O)N3CCCC(CO)C3)ccc21 +O=C(Cn1cnnn1)N1CCN(Cc2ccc(F)cc2Cl)CC1 +CCCC(=O)N1CCC2(CCCN(Cc3cccc(C)c3)C2=O)C1 +COc1cccc(C(=O)C2CCCN2C(=O)CC(C)C)c1 +CN(Cc1ccccc1)c1nnc(SCCO)s1 +O=C(CSc1ccc2c(c1)OCCCO2)Nc1ccccc1 +CCCN(C)c1ncc(S(=O)(=O)c2ccc(OC)cc2)c(N)n1 +CC(COc1ccc(F)cc1)NC(=O)NCc1cccnc1 +Cc1cc(C)n(CC(=O)Nc2cccc(C)c2C)n1 +Cc1ccc(-n2nnc(C(=O)Nc3ccc(C)c(C)c3)c2N)cc1 +CC(C)CN(C)C(=O)Cn1cnc2sccc2c1=O +CCOCc1ccc(CNC(=O)c2cc(C)n(CC)c2C)cc1 +CCCC(NCc1c(F)cccc1F)C(=O)OC +CCOC(=O)c1cnn(Cc2ccccc2)c1C(F)(F)F +O=C(NCc1cc(F)ccc1F)c1scnc1C1CC1 +Cc1sc(=O)n(CC(=O)Oc2ccccc2F)c1C +Cc1cc(Oc2ccc(C#N)cc2Cl)n2ncnc2n1 +CCC(=O)Nc1c(-c2ccc(F)c(F)c2)n[nH]c1CC +CNC(=O)c1cc2occc2n1Cc1ccccc1F +Cc1ccsc1C(=O)N1CCOC2C(OCC3CC3)CCC21 +Cc1ccc(CN2CCOC3(COCCN(S(C)(=O)=O)C3)C2)o1 +O=C(CCNC(=O)c1cc2ncsc2[nH]1)Nc1nccs1 +COc1cc(C#N)ccc1OC(=O)COc1ccc(Cl)c(C)c1 +CCCc1nc(-c2nc(-c3ccncc3)no2)cs1 +CCc1nn(C2C=CCCC2)c(=O)c(C#N)c1CC +CC(=O)c1ccc(OCC(=O)Nc2cc(C)n[nH]2)cc1 +CCNc1cc(NCCNC(=O)c2sc(C)nc2C)nc(C)n1 +CCN(CC)C(=O)c1cccc(NC(=O)C2CCCO2)c1 +Cc1noc(CCCC(=O)N2CCCC(C)C2)n1 +Cc1ccc2c(c1)C1(CC(O)=Nc3c1cnn3-c1ccccc1)C(=O)N2 +CCC(CC)n1ncc(C(=O)NC(C(N)=O)C(C)C)c1C +COCCCNC(=O)c1c[nH]c2cccc(F)c12 +CCc1nc(CC(=O)Oc2ccc(F)cc2)cs1 +Cc1ccccc1CCc1cc(NC(=O)c2cnn(C)c2)[nH]n1 +Cc1csc(CN(CC2CCCO2)C2CCCC2)n1 +CC(C)CCNC(=O)Nc1cccc(N2CCNC2=O)c1 +Cc1ccccc1C1CC(C)N(C(=O)c2ccccc2F)C1 +Cc1ccc(C(=O)NC2CCN(C(=O)C3CC3)CC2)o1 +COCCNC(=O)N(Cc1cccc(Br)c1)C1CC1 +CCc1cccc(OC(=O)CC(NC(N)=O)c2ccccc2C)c1 +Cc1nn(C)c(C)c1CN(C)C(=O)C1CCCCC1 +CC(NC(=O)Nc1ccc(SC(F)F)cc1)c1nccs1 +COc1ccccc1N(C)C(=O)c1cccc(C)n1 +CC1CC(C)CN(C(=O)COc2cc(=O)n(C)c3ccccc23)C1 +CC(=O)c1cccc(NC(=O)NCCOCC2CC2)c1 +Cc1cc2ncc(S(=O)(=O)C(C)(C)C)c(N)n2n1 +Cc1cc(C)n2nc(SC(C3CCCO3)C(F)(F)F)nc2n1 +CNC(=O)NCC(=O)Nc1ccc(CCC(F)(F)F)cc1 +COc1ccc(C(=O)Nc2cccc(OCc3cscn3)c2)nn1 +CSc1ccc(C(=O)N(C)Cc2nc3ccccc3[nH]2)o1 +Cc1ncc(CN(C)C(=O)c2cc(-c3cccc(Cl)c3)no2)s1 +Cc1cccc(C(C)CNC(=O)c2cscn2)c1 +Cc1noc(C)c1CC(=O)NCc1ccccc1Cl +CC(CO)CNC(=O)NCCNC(=O)c1ccccc1Cl +CC(C)(O)CN1CCN(C(=O)Nc2ccccc2)CC1 +CC1CCN(C(=O)CSc2nnc(-c3cccs3)o2)CC1 +NC(=O)CN(C(=O)C1CC2CCC1C2)C1CCCC1 +CCCN(CCC)c1nn2c(=O)c(C(=O)NCC)cnc2s1 +CC(C#N)CN(C)C(=O)c1cc2ccccc2oc1=O +Cc1csc(=NC(=O)c2cc(F)ccc2-n2cnnn2)[nH]1 +COC(=O)Nc1ccc(OCc2csc(-c3cnn(C)c3)n2)cc1 +Cc1csc(CN(C)c2ncnc3oc(C)nc23)n1 +CNC(=O)C(C)(C)CNC(=O)c1scnc1C1CC1 +O=C(NCC1CCCO1)NCC1(c2ccc(F)cc2)CCCC1 +CCC1CC(C(=O)Nc2cc3c(=O)[nH]cnc3cc2F)CCO1 +CC(C)COc1ccccc1NC(=O)Cn1cnnn1 +CC(=O)N1CC(C)(C)Cn2c(-c3cnccn3)nnc21 +Clc1cc2c(cc1CSc1ncccn1)OCO2 +Cc1cc(NC(=O)NCc2ccccc2Cl)n(C)n1 +Cc1cc(-c2nnc(CCC(=O)NCc3cccs3)o2)n(C)n1 +N#Cc1c[nH]c(C(=O)N2CC(=O)NC3CCCCC32)c1 +CC(C)(C)c1ccc(C(=O)N2CCC(Oc3cccnn3)CC2)cc1 +CC(NS(=O)(=O)c1cccc(C#N)c1)C(=O)N(C)C +COC(=O)C(C)CN(C)S(=O)(=O)N(C)C(C)C +Cc1cnn(CC2CC2)c1NC(=O)c1ccc(-n2ccnc2)nc1 +CCOc1ccc(-c2cc(C#N)c(=O)n(CC(C)C)n2)cc1 +O=C(NCCn1ccnc1-c1ncccn1)Nc1c(F)cccc1F +CCN(CCO)C(=O)NCc1cccnc1OC +Cc1cccc(NC(=O)Cc2ccc(F)cc2F)c1C(N)=O +CCOC(=O)N1CCN(C(=O)c2cccs2)CC1 +CCOc1ccc(NC(=O)Cn2nc(C)c3ccccc32)cc1 +CC(=O)N1CCN(c2ccccc2N2CC(C(N)=O)CC2=O)CC1 +COc1ccc2[nH]c3c(=O)n(Cc4nc(C)no4)cnc3c2c1 +O=C(NCc1nc(-c2cccs2)no1)c1cccc(F)c1 +C#CCNC(=O)c1ccc(S(=O)(=O)NCCC#N)cc1 +CCCC1CCC(NC(=O)Nc2cc(C)nn2C)CC1 +CC1CN(C(=O)C2CC(=O)N(Cc3ccco3)C2)CC(C)(C)O1 +O=C(Nc1cccnc1)C1COCC2CN(Cc3cccs3)CC21 +C#CCN1CCN(C(=O)NCC2(C)CCCO2)CC1 +O=C(Cn1ncc2ccccc2c1=O)N(CC1CC1)C1CCCCC1 +C=CCn1nnc(CO)c1-c1ccccc1Br +O=C(OCC(F)F)c1ccc(Oc2cccnc2)cc1 +O=C(CCN1CCOC1=O)Nc1ccc(F)cc1F +COc1cccc2sc(NC(=O)c3ccc[nH]3)nc12 +CC(C)CNC(=O)c1cc2ncc(Br)cn2n1 +CN(Cc1cccc(C#N)c1)C(=O)c1cn2cccnc2n1 +CCC(C)(O)CNC(=O)Nc1cccc(C)c1C(=O)N1CCCC1 +Cc1nc2sccn2c(=O)c1NC(=O)C1CCCC1 +COc1ccc(Cl)cc1NC(=O)CNC(=O)OCc1ccccc1 +COC(=O)CC(NC(=O)C1CCCC1)c1ccc(OC)cc1 +CCCCn1ncc(C(=O)Nc2cc(OC)ccn2)c1C +Cc1cc(C(=O)NC(CO)CC(C)C)c(NC(=O)C(C)(C)C)s1 +Cc1cc(=O)oc(C)c1C(=O)OC1CC2CCC1C2 +COc1ccc(CN(C(=O)C2CC2(Cl)Cl)C2CC2)cc1 +CC(NC(=O)c1cnn[nH]1)c1ccc(-n2cncn2)cc1 +CC(C)NC(=O)C(N)c1ccc(Cl)c(Cl)c1 +Cn1ccc(NC(CC(F)(F)F)c2ccccc2)n1 +C=CCn1cc(O)c(=O)cc1CN1CCN(CCO)CC1 +Cc1ccc(C(C)NC(=O)NC2(c3ccccc3F)CC2)o1 +Fc1ccc2c(c1Cl)CCNC2c1cncs1 +O=S(Cc1csc(C2CCCO2)n1)c1ccc(F)c(Cl)c1 +COCCNC(=O)CNC(=O)Nc1cc(C)cc(C)c1 +COc1cccc(CC(=O)c2cccc(OC)c2OC)c1OC +CCC(=O)NCC(=O)Nc1ccc(-c2nc3ccccc3n2C)cc1 +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)OCC(C)C +CCc1cccc(C)c1NC(=O)c1ccc(C(N)=O)cc1 +N#Cc1ccsc1NC(=O)CCN1CCCc2ccccc21 +CCC(=O)Nc1ccc2c(c1)CCC(=O)N2CC(C)C +CC(C)C(NC(=O)C1Cc2ccccc2S1)c1nc(C2CC2)no1 +COC(=O)Nc1cc(C(=O)OC)cc(C(=O)OC)c1 +Cc1ccc(-n2nc(C)c(S(=O)(=O)N3CCCCC3)c2C)cc1 +CCc1nc(C2CCCO2)sc1-c1nnc(NC)s1 +CC(c1ccccc1Cl)N(C)C(=O)c1cc2ccccc2oc1=O +COC(=O)C(c1cc(F)c(F)c(F)c1)N(C)C(=O)Cc1ccon1 +CCc1noc(-c2csc(C(=O)N3CCCC3)n2)n1 +CC(=O)Nc1ccc(F)c(NC(=O)N(C)Cc2cnn(C)c2)c1 +COc1ccc2c(c1)CN(C(=O)c1ccc(F)c(NC(C)=O)c1)CC2 +CCC1c2ccccc2CCN1C(=O)CNC(=O)NC +CCCCn1nnnc1SCC(=O)Nc1cccc(C)c1 +c1cnc(NCc2noc3c2CN(c2cnccn2)CC3)nc1 +CCCCN(CCO)C(=O)NCC1CN2CCCCC2CO1 +CCS(=O)(=O)NCc1cccn1Cc1cccc(C)c1 +CCOC(=O)c1nn(-c2cccc(C)c2)c(-c2ccco2)c1C#N +CC(CNC(=O)Cn1ncc(=O)c2ccccc21)Cn1cccn1 +O=C(c1cccc2cc[nH]c12)N1CCN(Cc2ccccc2)CC1 +COc1ccc2occ(CC(=O)Nc3ccc(F)cc3)c2c1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)CCc1nc(C(C)C)no1 +O=S(=O)(NCC(O)c1ccsc1)c1cc(F)ccc1F +C#Cc1cccc(N(CC(=O)NC)C(=O)COc2ccccc2F)c1 +C=CCNC(=O)c1cccc2c1-c1ccccc1C2=O +Cc1ccc(NC(=O)CCNC(=O)COc2cccc(C)c2)nc1 +CC(C)(C)c1nnc(CNc2ccc(Br)cc2F)o1 +COC(=O)c1c(C)[nH]c(C(=O)OCC(=O)NC2CCCC2)c1C +Cc1cccc(C(=O)N2CCCN(Cc3ccncc3Cl)CC2)c1 +CCCCOc1nc2ccccc2nc1N1CCOCC1 +O=C(COc1cccc(NC(=O)c2ccco2)c1)Oc1ccccc1 +CCOC(=O)c1c(N)c2cccnc2n(CCCOC)c1=O +CCOCC1CCN(C(=O)NCc2cc(C)cc(OC)c2)C1 +COCCc1nc2ccc(C(=O)NC3COc4ccccc43)cc2o1 +CCN(CC)C(=O)COC(=O)Cc1nn(C)c(=O)c2ccccc12 +COC(=O)CCCOc1cc(F)ccc1C(C)O +CCCn1c(CN2CCN(C(C)C(N)=O)CC2)nc2ccccc21 +CCOCCCNC(=O)Nc1ccc(Br)c(C)c1 +CCC1Oc2ccc(C(N)C(F)(F)F)cc2N(C(C)C)C1=O +CC(=O)N(C)Cc1cccc(NC(=O)NCCN2CCOCC2)c1 +Cc1ccc(C(=O)Nc2cccnc2N2CCCC2)cn1 +Cc1cc(CC(=O)NC(C)COc2ccccc2C(F)(F)F)no1 +Cc1nc(N(C)C)ncc1C(=O)N(C)CCc1noc(C2CC2)n1 +CC(OC(=O)c1cc(Cl)c[nH]1)C(=O)Nc1ccc(F)cc1 +COC(=O)C(CC(C)C)NS(=O)(=O)c1ccc(F)cc1F +Cc1ccc(SCCC(=O)Nc2c(C)n[nH]c2C)cc1C +Cc1cccc(-c2nc3ccccc3c(=O)n2CCN2CCOCC2)c1 +CNC(=O)c1cccc(NC(=O)c2c(C)cc(C)cc2C)n1 +Cc1ncc(C(=O)N2CCCC3(CCC(=O)N(C4CC4)C3)C2)c(=O)[nH]1 +Cc1cc(C(=O)NCCOc2ccc3c(c2)OCO3)c(C)n1C1CC1 +O=c1cc(CN2CCOCC2C2CC2)occ1O +CCc1[nH]nc(C(=O)Nc2ccc(Br)cc2)c1N +COc1ccccc1S(=O)(=O)NCC#Cc1ccccc1F +COc1ccccc1CC(C)NCc1c(C)noc1C +CCOC(=O)c1ncn2c1nnc1c(=O)n(C)cnc12 +CCOC(=O)c1c(C)oc2ncn(Cc3ccccc3C#N)c(=O)c12 +COCCNc1nnc(SCc2cccc(F)c2)s1 +CC(=O)c1cc(-c2ccc3c(c2)ncn3C)n(C)c1C +COc1ccc(OC)c(CNC(=O)c2ccc3c(c2)OCC(=O)N3)c1 +CC(CC#N)N1CCN(Cc2nc(-c3ccc(Cl)cc3)no2)CC1 +COc1ccc2ncnc(NCCN3CCOCC3)c2c1 +CCOC(=O)N1CCCC(C(=O)N2CCOC(C)(C)C2)C1 +COc1ccc(-c2nccnc2CC2CCN(C(C)=O)CC2)cc1 +CC(NC(=O)c1n[nH]c(=O)[nH]1)C(=O)N1CCc2ccccc21 +Cc1cccc(C2(C(=O)NCc3ccc(Cn4cncn4)cc3)CC2)c1 +COC(=O)N1CCC(NC(=O)C(C)n2cncn2)CC1 +CC(C)C(=O)Nc1cccc(NC(=O)c2c[nH]c3cccc(F)c23)c1 +COc1ccc2c(c1)C(N)C(CN1CCOCC1)CO2 +CN1CC(C(=O)NCCc2cc(F)cc3c2OCOC3)CC1=O +CNC(=O)COc1ccccc1CN1CCOC2CCCCC21 +CC1CCCC(NC(=O)Cn2nnc(-c3ccc(Cl)cc3)n2)C1 +CCCNC(=O)NCc1nc(-c2ccc(C)cc2)no1 +O=C(Nc1nccs1)c1ccccc1OCC1CCCO1 +O=C(Nc1cccc(C(=O)N2CCCCC2)c1)c1cnn2ncccc12 +Cc1cn(CC(=O)N2CCC(Nc3cccnn3)CC2)c2ccccc12 +c1cc(-n2cnnn2)ccc1OCc1nc(C2CC2)no1 +COC(=O)c1ccnc(NCc2ccc(=O)[nH]c2)c1 +O=C(CNC(=O)Cn1ccccc1=O)NCc1ccccc1 +CC1CCCCC1NC(=O)c1snc(C#N)c1N +Cn1nnc(NCc2ccccc2OCc2ccc(Cl)cc2)n1 +COc1ccc(Br)c(CNC(=O)C2CCC2)c1 +CC(C)(C)OC(=O)NC(Cc1c[nH]cn1)C(=O)CN +NC(=O)CCc1cccc(-c2nc3ccccc3o2)c1 +CCCOc1nc(N(CC(N)=O)C(C)C)ccc1N +CCn1c(C)cc(C(=O)CN2CCN(Cc3ccccn3)CC2)c1C +COc1ccc(-c2cc(-c3ccco3)nc(N)n2)cc1 +COc1ccc(OC)c(C(=O)Nc2c(C(N)=O)oc3ccccc23)c1 +COc1ccccc1C(=O)Nc1c(C)nc2sc(C)c(C)n2c1=O +Cc1cccc2c1CNCC2C(=O)NC1CCC(O)CC1 +CC(C)NC(=O)Cn1c2c(c(=O)n3ncnc13)CCC2 +CN(Cc1ccc(F)cc1)C(=O)CSc1nnc(N)[nH]1 +CC(C)(C)OC(=O)n1cnc2c(Cl)ccnc21 +Nc1nc2c(ncn2C2CC(CO)C2CO)c(=O)[nH]1 +Cc1ccc(CNC(=O)NCCCn2nc(C)cc2C)cc1 +CC(C)c1noc(CCCC(=O)Oc2cccc(Cl)c2)n1 +O=C(NCCCOCC(F)(F)F)c1ccccc1Cl +O=C(NCC(F)(F)F)c1ccccc1NC(=O)C1CC=CCC1 +COC(=O)C(CC(C)C)NC(=O)Nc1ccc(S(N)(=O)=O)cc1 +COCc1nnc(NC(=O)CC2C(=O)Nc3ccccc32)s1 +FC(F)(F)c1nnc2ccc(N3CCCC3)nn12 +COc1cc(OC)c(NC(=O)NCCc2ccc(C)nc2)cc1F +COc1ccccc1Oc1ccc(NC(=O)C(C)NC(C)=O)cc1F +CC(=O)Nc1ccc(NC(=O)C(C)Oc2ccc(Cl)cc2)cc1 +Cc1ccoc1C(=O)N1CCCC1c1c(C)nn(C)c1C +CC(C)(C)c1ccc(S(=O)(=O)Nc2nccs2)cc1 +C=CCN(C(=O)c1cc(OC)c(OC)c(OC)c1)c1ccccc1 +Cc1c(Cl)cccc1-c1ccc(C(=O)NCCCO)o1 +N#Cc1ccc(C(=O)OCC(=O)c2ccc(F)cc2)cc1 +Cc1ccc(NC(=O)CSc2nccn2C)cc1F +COc1ccc(CCOc2ccc(CO)cc2OC)cc1 +Cc1cnn(Cc2cccc(Cl)c2)c1NC(=O)c1cnc[nH]1 +O=C(COc1cc(Cl)cc(Cl)c1)Nc1nccs1 +COC(=O)Cn1c(CCCNC(C)=O)nc2ccccc21 +O=C(Nc1ccc(C(=O)N2CCCCC2)nc1)NC1CC1 +CNC(=O)CN1C(=O)CNc2cc(Br)ccc21 +Cc1cc(C)n(-c2nc3c(c(=O)n(C)c(=O)n3C)n2C(C)C)n1 +CCc1ccc(CCC(=O)NCc2ccc(OC)nc2)cc1 +O=C(Nc1ccccn1)c1cncc(C(F)(F)F)c1 +Cc1cc(OCC(=O)N2CCCCCC2)ccc1N +CSc1ncc(CO)c(N2CCC(C)CC2)n1 +CN(C)C(=O)CN1CCN(C(=O)CCCc2cccs2)CC1 +CCOC(=O)CN(CC)C(=O)c1cc(N)ccc1C +Cc1cc(C(=O)N2CCC3(CCC(=O)N(CCO)C3)CC2)nc(C)n1 +CC(C(=O)Nc1ccccc1CN1CCc2ccccc21)n1cncn1 +COc1ccc(NC(=O)NCCC(=O)N2CCCC2)cn1 +COc1ccc(C)cc1NC(=O)C1CCN(S(C)(=O)=O)CC1 +Cc1cc(C(=O)NCc2ccnc(OC3CCOCC3)c2)c(C)s1 +O=C1CCCCN1CCC(=O)N1CCCC(Nc2ccccc2)C1 +COCC(C)NC(=O)c1cc(Cl)cc(Cl)c1 +COC(=O)CC(NC(=O)Nc1ccc(C(C)=O)cc1)c1cccs1 +Cc1ccc(-n2ncc(C(=O)Nc3ccncc3)c2C(F)(F)F)cc1 +CC(C)C(C)NC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CN(CCN1CCCCC1=O)Cc1nccs1 +NC(=O)c1c(C(F)(F)F)ccc(Cl)c1Cl +Cc1ccc(-c2ncc(CN3CCCC(c4nncn4C)C3)s2)o1 +COC(=O)c1ncn(Cc2nc(CCc3ccccc3)no2)n1 +CC(=O)c1ccc(N2CCN(Cc3nnc(C4CC4)o3)CC2)c(F)c1 +O=S(=O)(c1ccc(F)cc1)N1CCCc2ccc(O)cc21 +O=C(NC(CCO)C1CC1)c1c(F)cccc1Br +CCc1nc2n(n1)CCCC2NC1CCSc2ccc(Cl)cc21 +CN1CCN(S(=O)(=O)Cc2ccc(Cl)cc2)CC1 +COCC1CN(Cc2ccoc2)Cc2cn(C)nc21 +Cc1cccc(N2CCN(CC(=O)NCC(F)(F)F)CC2C)c1 +COCc1cc(C(=O)N2CC(C(C)C)Nc3ccccc32)no1 +N#CC(C(=O)Cc1ccc2c(c1)CCCC2)c1nc2ccccc2[nH]1 +COc1ccc(C#CCNC(=O)c2cc(-c3ccco3)on2)cc1 +C=CCNc1nnc(SC2CCN(c3ccccc3)C2=O)s1 +O=C(NCCc1ccc(F)c(Br)c1)NCC(F)(F)F +O=C(NCC(F)F)NC(CO)Cc1ccccc1 +CCN(CCO)C(=O)c1cc2ccc(OC)cc2oc1=O +CNC(=O)c1cccc(CNC(=O)c2cnc3ccc(C)cn23)c1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)N(C)CC1CC1 +O=S(=O)(c1cc(F)cc(F)c1)N1CCC(O)CC1 +COc1ccc(CNC(=O)N(C)CCc2cccs2)cn1 +CC(NC(=O)N1CCN(CC(N)=O)CC1)c1ccccc1 +CC(=O)c1cc(C(=O)NC(C)Cc2ccccc2F)n(C)c1 +Cc1nn2c(NCc3cnn(C)c3C)cc(-c3ccccc3)nc2c1C +Cc1cc(=O)[nH]c(N2CCN(c3ccc(F)cc3)CC2)n1 +O=C(CCCn1cnc(-c2ccccc2)cc1=O)NCc1cccnc1 +COCc1cccc(CNC(=O)CNC(=O)Nc2cccc(C)c2)c1 +CC(C)(Cc1ccc(Br)cc1)C(=O)c1cncnc1 +CC1Sc2ccc(C(=O)C3CCCC3)cc2NC1=O +O=C(NCc1csc(=O)[nH]1)c1cccc(OCC(F)F)n1 +O=C(CC1C=CCC1)NCc1cccnc1Oc1cccc(F)c1 +CC(C)Cn1nccc1NC(=O)Cc1cccc(OCC#N)c1 +N#CC1(C(=O)N2CCN(C(=O)c3ccccc3O)CC2)CCC1 +N#CCCN(CC1CC1)S(=O)(=O)Cc1ccc(Cl)cc1C#N +CC(C)CC(C)OC(=O)CCn1nnc2ccccc2c1=O +CC=CCOC(=O)Cc1csc(NC(=O)C(C)C)n1 +CCc1noc(CN(C)C(=O)c2cccc(-c3ccoc3)c2)n1 +Cc1csc(CN2CC(c3ccccc3)OCC2(C)C)n1 +CC(C)CNC(=O)C(N)c1c(F)cc(F)cc1F +CCCCNC(=O)c1sc(-n2nc(C)c(C)c2O)nc1C +O=C1CN(C(=O)CCCOc2cccc3ccccc23)CCN1 +COC(=O)C(CNC(=O)C(C)C)Oc1ccc(F)cc1 +C#Cc1cccc(NCC(=O)NC2(C#N)CCCCC2)c1 +O=C(Nc1ccc(C(=O)NC2CCCCC2)cc1)c1cccnc1 +CN(C1CCCCC1)S(=O)(=O)Nc1cccc(CO)c1 +COC(=O)C1CC(Oc2ccccc2Cl)CN1 +CC(C)CC1COCCN1C(=O)C1CC1c1ccccc1 +CCCCOc1ccc(OC)cc1NC(=O)c1ccncc1F +CC(C)n1cnnc1S(=O)(=O)CC(=O)Nc1cccc(F)c1 +CCN(CC)C(=O)c1ccc2c(c1)N(C(=O)NC)CC2 +CC(NC(=O)NC1CC1c1cccc(Cl)c1)C1CCCO1 +Cc1ccc(C(=O)N(c2nc(C)cs2)C2CC2)cn1 +CCN1CCN(C2CCN(C(=O)Cc3cccc(OC)c3)CC2)C1=O +Cc1noc(CCC(=O)NCC(C)(C)c2ccccc2Cl)n1 +Cc1ccccc1C(CC(=O)OCC1CC=CCC1)NC(N)=O +COc1ccc(C(=O)N2CCC2)cc1S(=O)(=O)N(C)C +CCN(C(=O)c1c(C)[nH]c(C(C)=O)c1C)C1COCC1O +CC(Nc1nc2ccccc2o1)C(=O)NC1CCCC1 +COc1ccc(-c2nc3cc(C)c(C)cc3n2CCO)cc1OC +COC(=O)c1c(NCCc2ccccc2)c2ccc(F)cc2[nH]c1=O +Cn1nnnc1COc1cccc(C(=O)Nc2ccon2)c1 +CSc1ncc(CNC(=O)C2CC(=O)Nc3ccc(F)cc32)n1C +Cc1nnc(SCc2ccc(C(F)(F)F)cc2)n(N)c1=O +CC(C)c1nc(CN(C)C(=O)c2ccc(-c3nc[nH]n3)cc2)cs1 +c1ccc(Cn2ccnc2CCNCc2cccs2)cc1 +COC(=O)c1ccc(NCC(=O)Nc2cccc(C(C)=O)c2)cc1 +CCOc1ccc(CNc2c(C)cc(C)cc2C)cc1OC +COc1ccc(C(=O)NCCN2CCOCC2)c(OC)c1 +CCc1ccccc1OCC(=O)Nc1ccc2c(c1)OCC(=O)N2 +COc1ccc(S(=O)(=O)NCC(OC)c2ccccc2C)c(C)c1 +CN1C(=O)Cc2cc(NC(=O)c3ccc4ccccc4c3)ccc21 +CCc1cccc(OC(=O)C2CC(=O)N(C(C)C)C2)c1 +O=C(Nc1ccc(-n2cnnn2)cc1)c1ccccc1F +CNc1ncc(S(=O)(=O)NCCOC)cc1Cl +C=CCNC(=O)Nc1ccc(NC(=O)c2cc(C(N)=O)cs2)cc1 +Cc1csc(=O)n1CCSc1nnc(-c2ccccc2)n1C +O=S(=O)(N1CCCCCC1)N(Cc1cccc(F)c1)C1CC1 +CCOC(=O)c1cc(N)c(N2CCOCC2)c(Cl)c1 +CCCCc1nc2c(N)cccc2n1CC(=O)NCC(C)C +Fc1ccccc1CNc1ncnc2ccccc12 +Cn1ccc(NC(=O)c2ccc(Sc3ccccc3Cl)nn2)n1 +CCn1nc(C)c(CN(C)C(=O)c2cccs2)c1C +Cc1ccc(C(C)N(C)C(=O)Cn2c(=O)[nH]c3ccccc32)cc1 +CC(c1nccn1Cc1ccccc1)C(F)(F)F +COc1ccc(SCC(=O)Nc2nnc(-c3ccco3)o2)cc1 +CCN(CC)C(=O)c1cccc(NC(=O)CN(C)c2ccccc2)c1 +Nc1cc(CCOc2cccc3c2CCCC3)nn1CCO +COc1ccc(CC(=O)OCc2cc(C#N)ccc2F)cc1OC +NC(c1nc2c(s1)CCC2)c1cc(Cl)ccc1F +O=C(CSc1ccc(F)c(F)c1)Nc1cccc(-n2cnnn2)c1 +Cn1c(N)nnc1SCCOc1c(Cl)cccc1Cl +CCCCN(C)C(=O)NC1COc2c(cccc2OC)C1 +CC(NC(=O)C1CC(=O)N(Cc2ccccc2)C1)c1ccncc1 +C=CCN(CCO)C(=O)Nc1ccc(Cl)c(Br)c1 +Cc1ccc(CNCc2cc3cc(C)ccc3n3nnnc23)cc1 +Cc1ncc(C(=O)NCc2ccc(Cl)cc2)c(C)n1 +COc1ccc(NC(=O)c2cc(OC)no2)c(OC)c1 +Cc1ccn(-c2cccc(NC(=O)COc3c(C)nn(C)c3C)c2)n1 +COc1ccc(-n2c(CN3CCOC(C)C3)nc3ccccc32)cc1 +COCCC(=O)NC1CCN(c2c(F)cccc2F)C1=O +CCc1nnc(NC(=O)c2cn(C)nc2-c2ccc(F)cc2F)s1 +Cc1cc2cc(NC(=O)c3cc(-c4cccnc4)on3)ccc2[nH]1 +Cc1nc(C(C)C)sc1C(=O)NCCN1CCc2ccccc21 +COc1ccc2c(c1)OCC(C(=O)NC(C)C(=O)N1CCCC1)C2 +Cn1nnnc1NCc1ccc(-c2ccc(Br)cc2)o1 +COc1ccc(-c2nc(CNC(=O)C3CC3c3ccccc3)n[nH]2)cc1 +CC(C)CNC(=O)c1cc(=O)c(OCc2ccccc2F)co1 +COC(=O)c1ccc(NC(=O)COc2ccccn2)cc1 +O=C(NCc1ccc(OCC(F)(F)F)nc1)N1CCCC(CO)C1 +NC(=O)Nc1ccc(C(=O)Nc2nnc(C3CC3)s2)cc1 +Cc1ccccc1C(=O)N1CCCCC1CNC(N)=O +N#Cc1cc(N)ccc1Nc1ccc(Cn2cncn2)cc1 +CC(=O)NCCNC(=O)C(C)Oc1ccc(C#N)cc1 +Cc1cc(C(=O)NCc2ccc(F)cc2)c(C)n1C1CC1 +Cc1c(C(=O)NC(C)c2ccco2)sc2ncn(C)c(=O)c12 +COc1ccccc1S(=O)(=O)NCC#Cc1ccc(C(N)=O)cc1 +COc1ccccc1CNC(=O)COc1nnc2ccccn12 +Cc1ccc(NC(=O)N2CCN(C(C)(C)CO)CC2)cc1Cl +CC#CCNC(=O)NCC1(c2cc(C)ccc2OC)CCOCC1 +CCc1nc(NC(=O)CNC(=O)c2ccc(OC)cc2)sc1C +COc1ccccc1CNC(=O)c1ccc(C(F)(F)F)nc1 +CC(Nc1ccc(S(C)(=O)=O)cc1S(C)(=O)=O)C1CC1 +CCOc1cccc(CO)c1OCc1ccc(F)cc1 +CC(NC(=O)CCc1ccco1)c1nc(-c2ccc(F)cc2)no1 +CCC(C)n1ncc(C(=O)NCC2CCCC2O)c1C1CC1 +Cc1ccccc1-c1nnc(SC(C)C(=O)NCC(F)(F)F)o1 +CC(C)NC(=O)c1cnc(CCc2ccccc2)nc1N +COc1ccccc1C(C)NC(=O)c1ccc(NC(N)=O)cc1 +CC1CCCN(C(=O)c2c(-c3ccncc3)cnnc2N)C1 +COC(=O)CN1C(=O)c2cccnc2Oc2ccc(C)cc21 +CCCCNC(=O)CS(=O)(=O)c1ccccc1 +COc1ccccc1CC(=O)Nc1cccc(C#N)c1 +Nn1c(SC2CCCc3ccccc32)nnc1C(F)(F)F +Cc1noc(C)c1S(=O)(=O)Oc1ccc(CC#N)cc1 +Nc1ccc(=O)n(CC(=O)N2CCc3ccccc3C2)c1 +CCOC(=O)c1cnn(C)c1C(C)c1ccccc1 +O=C(CCNC(=O)C12CC3CC(CC(C3)C1)C2)NC1CCCC1 +C=CCn1c(C)nnc1SC(C)C(=O)Nc1c(C)cc(C)cc1C +CCOc1cc(C)ccc1NC(=O)NCc1nc(C)cs1 +O=C1C(Sc2ncc3ccccn23)CCN1c1c(F)cccc1F +COc1ccc(CNC(=O)c2ccc(-n3ccnn3)cc2)cc1C +CC(C)CC1CCCCCN1C(=O)NCCC(=O)N(C)C +COc1ccccc1NC(=O)c1cc2sccc2n1C +CCOC(=O)Cn1c2ccc(Cl)cc2c2nc(C)sc21 +N#Cc1cccnc1NCc1ccccc1-n1cccn1 +Cc1noc(COC2CCCN(S(=O)(=O)c3cccnc3)C2)n1 +Cc1nn(CCCCC(C)(N)C#N)c(C)c1Cl +Cc1ccsc1C(=O)NCCCn1cncn1 +Cc1ccc(CCC(=O)N2CCCCC2CNC(N)=O)c(C)c1 +c1coc(-c2cc(Cn3ccnc3-c3ccc(-c4cc[nH]n4)o3)no2)c1 +CCSc1cccc(C(=O)Nc2ncnc3c2CCC3)c1 +Cc1nc(CNC(=O)CCn2ncc3c(Cl)cccc32)cs1 +CC(C)NC(=O)CCNC(=O)c1cc(Cl)c[nH]1 +C#CCNS(=O)(=O)c1cccc(C(=O)N2CCOCC2C2CC2)c1 +COc1cccc(CC(=O)N(CC(=O)N(C)C)CC(F)(F)F)c1 +CCCc1[nH]nc(-c2cccc(OC)c2)c1NC(=O)CC +O=C(NCc1nc2ccccc2[nH]1)c1cccs1 +NC(=O)C1CCN(c2nc(C(F)(F)F)nc3ccccc23)CC1 +CC(=O)Nc1cccc(C(C)Nc2ccn(C)n2)c1 +OCc1nnn(Cc2ccc(F)cc2)c1-c1ccc(F)c(F)c1 +CC(C)CNC(=O)NCc1ccc(CN2CC(C)OC(C)C2)cc1 +CC1CN(CCCNC(=O)c2cnccn2)CC(C)O1 +CC(C)CC(=O)Nc1ccc(NC(=O)N2CC(CO)CCC2C)cc1 +COc1ccc(NC(=O)NCC(=O)N2CCCCC2)c2cccnc12 +COc1ccc(CN(C)S(=O)(=O)c2cn[nH]c2)cc1 +COC(=O)CNC(=O)c1oc2c(ccc3ccccc32)c1C +CCC(CC)C(=O)N1CCN(c2ccnc(N3CCCCC3)n2)CC1 +CCCC(=O)Nc1cc(C(=O)NCC2CCCO2)ccc1C +CCCC(C)NC(=O)Cn1c(=O)n(C)c2ccccc21 +COC(=O)c1cccc(CC(=O)n2ncc(C#N)c2N)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1cn2cccnc2n1 +COCc1nnc(NC(=O)CCn2ccc3cc(OC)ccc32)s1 +CCN(C(=O)c1ccccc1NC(=O)c1cccnc1)c1ccccc1 +CC(=O)NCC(=O)Nc1ccc(OC(F)F)c(Cl)c1 +O=C(COC(=O)COc1ccccc1Cl)NC1CCCCC1 +Cc1ccc2cc(-c3nc(-c4ccc(C#N)cn4)no3)ccc2n1 +Nc1c(NCCN2CCOCC2)ncnc1Nc1ccc(Cl)cc1 +CN(C)c1ncccc1C(=O)NC12CC3CC(CC(C3)C1)C2 +CC(C)CCC(C)NC(=O)N1CCCN(c2ncccc2C#N)CC1 +N#CCCN1CCN(c2cc(Cl)cc(Cl)c2)CC1 +CCOc1cccc(CNC(=O)CNC(=O)c2cccc(F)c2)c1 +N#Cc1cccc(NC(=O)c2csc(Nc3ccccn3)n2)c1 +CCC(=O)N1CCc2cc(-c3ccc(C(=O)N4CCCC4)cc3)ccc21 +COc1ccc(CNC(=O)Cn2nnc(-c3ccccc3)n2)cc1 +CC(NC(=O)CCc1cc(Br)cs1)C1CCCO1 +Cc1ccc(C(=O)n2c(N)c(C#N)c3ccccc32)cc1 +O=C(CN1CCN(CC(O)CN2CCOCC2)CC1)N1CCCC1 +COc1ccc(Cn2c(CO)nc3cccnc32)cc1 +COc1ccc(NC(=O)c2sc3nc[nH]c(=O)c3c2C)cc1Cl +N#Cc1cccc(CS(=O)(=O)NC2(c3ccccc3)CCC2)c1 +Cc1ccccc1C(=O)OCCn1c(=O)oc2ccccc21 +COc1ccc(C(=O)N2CCCC(n3cncn3)C2)c(C)c1 +O=C(CNC(=O)C1CCc2ccccc21)Nc1ccc(F)c(F)c1 +COc1ccc(CCNC(=O)c2ccccc2N)cc1OC +CCNC(=O)Nc1ccc(C(O)C2COCC(=O)N2CC)cc1 +CCn1cc(O)c(=O)cc1CN(C)Cc1ccccc1 +O=C(NCc1ccncc1)c1ccc(S(=O)(=O)c2ccccc2)o1 +CC1(C)Oc2cccc(N)c2N(CC(=O)N2CCCC2)C1=O +COc1ccc(CNc2nc(SC)n[nH]2)cc1 +Cc1ccc(O)c(C(=O)OCC(=O)N2C(C)CCCC2C)c1 +O=C1CN(Cc2nc3ccccc3c3ccccc23)CCN1 +NC(=O)c1csc(C(=O)NCCc2c(F)cccc2F)c1 +Cc1ccc(=O)n(CC(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)n1 +Cc1cnn(CCC(=O)Nc2sc(-c3ccccc3)cc2C#N)c1 +COC1CN(C(=O)C2CC2c2ccccc2Cl)C1 +COc1ccccc1-n1cnnc1S(=O)(=O)Cc1c(C)noc1C +CN(C)S(=O)(=O)NCc1ccccc1N1CCCC1 +Cc1cc(N)ccc1NC(=O)COc1cccc(Br)c1 +CC(NC(=O)c1ccc2[nH]cnc2c1)c1ccc(N2CCCC2=O)cc1 +CCOC(=O)c1cnn(C(C)(C)C)c1C(F)(F)F +CCOc1cc(NCC2CCN(C(=O)OC(C)(C)C)CC2)ncn1 +O=C(CCC1NC(=O)c2ccccc2NC1=O)NC1CCCCCC1 +CC(C)c1cccc(NC(=O)Cn2cnc3ccccc3c2=O)c1 +CC(NCc1ccncc1)C(=O)N1CCc2ccccc21 +Cc1ccccc1SCC(=O)N(C)CCC(F)(F)F +Cc1cc(NC(=O)CNc2ccccc2Br)no1 +CCOc1ccc(NC(=O)C2(C#N)CCCC2)cc1OCC +CCOC(=O)c1c(NCCOC)c2cc(F)ccc2[nH]c1=O +Cc1cc(N2CCCC(c3nccnc3-n3ccnc3)C2)ncn1 +Cc1c(C(=O)N2CC3CCC2C3)nnn1-c1cccc2cnccc12 +N#CCn1ccc(C=Cc2ccc(F)cc2)cc1=O +O=c1cc(-c2ccccc2)cc(-c2ccccc2)n1CCO +CC(c1cccnc1)N(C(=O)Nc1ccccc1OC(F)F)C1CC1 +CC(=O)c1csc(NC(=O)CCc2ccccn2)n1 +CCCCOC(=O)CSc1nc2ccsc2c(=O)n1C +Cc1ccc(CNc2cccnc2-n2ccnc2C)c(C)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1ccc(NC(C)=O)cc1 +COc1cc(CN(C)C(=O)Nc2cc(C)on2)ccc1SC +O=C(NC(c1ccccc1F)C1CCCC1)c1n[nH]c(=O)[nH]1 +COc1cc2c(cc1CNC(=O)c1cc(=O)c(OC)c[nH]1)CCC2 +CS(=O)(=O)c1ccc(F)c(NC(=O)CCOCC(F)(F)F)c1 +COc1cc(OC)c(NC(=O)c2cc(C(C)C)n(C)n2)cc1F +CCCCCNC1C(=O)Nc2cccc(Br)c21 +O=C(CCC(=O)N1CCOCC1)OCc1ccccc1F +COCCCNC(=O)NCc1ccc(OC)nc1 +N#Cc1cccc(C(=O)NCCc2ccncc2)c1 +c1ccc(CN2CCCn3c(nnc3Cn3cccc3)C2)nc1 +O=C(NCCCOc1cccc(Cl)c1)c1scc2c1OCO2 +Cc1ccccc1S(=O)(=O)N(C)C(C#N)c1ccccn1 +FC(F)(F)c1cccc(N2CCC(n3cncn3)CC2)n1 +COC(=O)CNC(=O)C(N)c1cccc(C)c1C +Cc1cc(F)ccc1CCNC(=O)c1ccccc1SCC(N)=O +COCCN(Cc1ccoc1)C(=O)NC1CCCC1 +CC(C)CCN(CC(=O)N1CCNCC1)C(=O)c1cccc(F)c1 +COc1ccccc1CCCn1cnc(C#N)c1C#N +CCOc1cc(F)ccc1NC(=O)c1ccc(NC(=O)C2CC2)cc1 +N#Cc1ccc(N2CCCC(CO)(Cc3ccccc3F)C2)nc1 +Cc1nccn1S(=O)(=O)c1ccc(C(C)C)cc1 +C#CCNC(C(=O)Nc1ccc(OC)c(Cl)c1)c1ccccc1 +O=C(NCC1CC=CCC1)NC1c2ccccc2CC1O +CCC1(C)Cc2c(c(=O)n(-c3ccccc3)c3ncnc(N)c23)CO1 +CCCCOc1cccc(-c2ncc(C(=O)NC)c(N)n2)c1 +OCc1ccc(C2NCCc3cc(Cl)cc(F)c32)cc1 +CC(C)n1ccc(C(=O)N2CCNC(=O)C2Cc2ccccc2)n1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)N(C)Cc1ccncc1 +COCCOc1ccccc1NC(=O)c1cccc(NC(C)=O)c1 +CC(C)OCCC(=O)NCc1ccc(C(=O)N2CCCCC2)cc1 +CC(CNC(=O)Cc1ccc(-n2cnnn2)cc1)c1ccc(F)cc1 +Cc1cc(F)ccc1NC(=O)CC(C)n1cccn1 +NC(=O)C1CCN(C(=O)CS(=O)(=O)c2cc(F)ccc2F)CC1 +CC(Nc1ccn(C)n1)C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cn1ncc2c(=O)n(CCC(=O)NCCc3ccccc3)cnc21 +CC(=O)Nc1ccc(C(=O)Nc2cccc3cccnc23)cc1 +NS(=O)(=O)c1ccc(N2CCC3CCCCC32)cc1C(F)(F)F +CCc1noc(CC)c1CC(=O)Nc1cc(C(=O)NC)ccc1OC +Cc1ccc(F)c(NC(=O)Cc2cn3ccsc3n2)c1 +O=C(CCc1cnn(-c2ccccc2)c1)Nc1cccc2cnccc12 +Cc1cccc2nc(CNC(=O)c3ccc(O)c(Cl)c3)n(C)c12 +Cc1c(C)n(C2CCCCC2)c2ncnc(NCc3ccccn3)c12 +COc1ccc(NC(=O)c2cc(-c3cccs3)[nH]n2)c(OC)c1 +COc1ccc(CC(=O)N2CCNCC2)cc1F +O=C(NCC(F)(F)F)C1CCCN1c1nc2ccccc2o1 +Cc1ccc(NC(=O)C(C)Sc2nc(N)cc(N)n2)c(C)c1 +O=C(c1ccc(-c2cc[nH]n2)nc1)N1CCC(N2CCOCC2)CC1 +O=c1cc(CN2CCCc3ccccc32)nc2sccn12 +COC(C(=O)Nc1cccc(O)c1)c1ccccc1 +CC1CN(C(=O)COC(=O)c2ccc(Cl)c(N)c2)CC(C)O1 +Cc1ccc2cnn(C(=O)Nc3ccccc3)c2c1 +CNc1nnc(-c2cccn(CCCOC)c2=O)s1 +O=C(Cc1ccc(F)cc1)Nc1cc(CO)ccn1 +C=CCN(Cc1nccn1Cc1ccccc1F)C(=O)CC +COc1ccc(-c2nnc(NC(=O)c3cccs3)s2)c(OC)c1 +CCOC(=O)c1cnc(SC)nc1NCc1ccc2c(c1)OCO2 +CCc1[nH]c(C(=O)N2CCOCC2C2CC2)c(C)c1C(=O)OC +COc1cccc(CNc2nc(C(F)(F)F)cs2)c1 +O=C(CCCc1c[nH]c2ccccc12)N1CCOc2ccc(F)cc21 +Cc1cc(Br)cc(C)c1NCCC(=O)N(C)C +COc1ccnc(NC(=O)C2(c3cccc(F)c3)CCC2)c1 +CN(CC1CCCCC1)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +CN1C(=O)Cc2cc(C(=O)c3cccc(N)c3)ccc21 +Nn1cnc2c(cnn2-c2cccc(Cl)c2)c1=O +Cc1ccccc1-n1ncc(C(=O)Nc2ccc3c(c2)COC3)c1C +COc1ccc(CNC(=O)C(C)(C)C)cc1OC +CC(C)c1csc2nc(-c3ccncc3)c(CC#N)n12 +Brc1ccc2nnc(-c3cocn3)n2c1 +COC(=O)NCCOC(=O)c1cc(F)cc(Br)c1 +CCCCCn1nnc(S(=O)(=O)C(C)C)c1N +N#Cc1cnc(NC(=O)C2COc3ccccc3O2)s1 +N#Cc1ccc(NC(=O)CCSc2nnnn2C2CCCC2)cc1 +Cc1noc(C)c1CCc1ncncc1Br +Cc1cccc(NC(=O)CSc2ccccc2)c1C(N)=O +CC(O)CN1CCN(C(=O)Cn2c(=O)[nH]c3ccccc3c2=O)CC1 +Cc1nc(C)c(C)c(Nc2ccc3c(c2)CC(=O)N3)n1 +Cc1ccc2c(C(=O)NCC(C)C)nccc2c1N +CC1CCc2n[nH]c(C(=O)N(C)CCc3ccncc3)c2C1 +Cn1c(SCc2cc(=O)c(O)co2)nnc1-c1ccccc1 +CCOC(=O)CC(C)CNC(=O)c1ccc2c(c1)CCO2 +CC(=O)NCCNC(=O)c1ccc(OCC2CCCO2)cc1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)NCCc2ccccn2)c1 +CC(C(=O)NCCNC(=O)c1ccoc1)n1ccnc1 +O=C(NCC(=O)N1CCc2cc(F)ccc2C1)OCc1ccccc1 +Cc1cc(NC(=O)c2n[nH]c3ccccc23)n(Cc2ccccn2)n1 +COCc1ccccc1C(=O)NCCc1nc2ccc(F)cc2[nH]1 +CSc1ccccc1NC(=O)c1cc2ccccc2c(=O)o1 +CC(C)C(=O)N(C)Cc1ccc(C(=O)N(C)CC(O)C2CC2)cc1 +O=C(c1cc2c(s1)CCCC2)N1CCC(CO)C1 +COc1cc(-c2noc(CCC(=O)c3cc(C)sc3C)n2)ccn1 +COc1cccc(CN(C(=O)c2cnc(C3CC3)nc2)C2CC2)c1 +CCOC(=O)N1CCN(C(=O)c2c(O)cc(F)cc2F)CC1 +COc1cc(C(=O)N2CCN=C2c2ccccc2)cc(OC)c1OC +CC(C)c1csc(NC(=O)Cn2nc(-c3ccccc3)oc2=O)n1 +CC(C)C(NC(=O)CCc1ccccc1)C(=O)N1CCCC1 +COC(=O)c1ccc(CN2CC(C)OCC2C)cc1F +COc1cc(C(=O)OC(C)c2nc(C)no2)cc(OC)c1C +CCC(CC)n1ncc(C)c1NC(=O)c1cc(-c2ccsc2)n[nH]1 +O=C(NCc1ccco1)C1(c2ccccc2)CCOCC1 +CCNC(=O)CNc1cc(NC(C)=O)ccc1F +Cc1n[nH]c(C)c1C1COCCN1C(=O)c1sccc1C#N +CN(C)S(=O)(=O)NCCC1CCN(CC(F)(F)F)CC1 +COC(=O)CNC(=O)C1(c2ccc(OC)cc2)CCCCC1 +CNC(=O)C1CCN(S(=O)(=O)c2ccc(C)c(Cl)c2)CC1 +CC(C)C(CO)NC(=O)c1ccc2c(c1)OCO2 +CCN1CCN(C(=O)C(C)Sc2nncs2)CC1 +CC(C)(C)C(=O)NCC(=O)N1CCN(c2ncccc2F)CC1 +Cc1cnc(C(=O)N2CCN(S(=O)(=O)N3CCCC3)CC2)cn1 +Cc1cccc(S(=O)(=O)NCc2ccncc2)c1 +Cc1nc(SCC(=O)Nc2ncccn2)c2ccccc2n1 +Cc1ccc2cc(C(=O)NC(C)c3ccccn3)[nH]c2c1 +Cn1cccc1C(=O)N1CCc2ncnc(-c3ccoc3)c2CC1 +O=C(NCc1ccoc1)Nc1ccccc1OC1CCCC1 +CCN(C(=O)Nc1cccc(NC(C)=O)c1)C(C)c1ccc(F)cc1 +COc1ccc(-n2c(C)c(C)c3c(N)ncnc32)cc1 +Cn1ccc(NC(=O)Cn2c3ccccc3c(=O)c3ccccc32)n1 +CCOc1cc(F)ccc1NC(=O)NC1(c2noc(C)n2)CCCC1 +Cc1cc(CN2CCc3c(nnn3C)C2COCC2CC2)no1 +COc1c(O)c(C(C)=O)c(OC)c(OC)c1OC +Cc1cc(OCc2cccc(F)c2)nc(-c2cnccn2)n1 +CC(Nc1ccc2c(c1)oc(=O)n2C)C(=O)N(C)Cc1ccccc1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1cc(C)cc(C)n1 +N#CC(C(=O)c1cc2ccccc2s1)c1ccccn1 +CC(=O)N(C)c1ccc(NC(=O)CC2CCCCC2)cc1 +CN(c1ccc(N)c(F)c1)S(=O)(=O)c1ccc(F)cc1 +CCOc1ccc(C(C)NC(=O)NC(C)C(=O)N2CCCCC2)cc1 +C#CCNC(=O)C(C)NC1CCN(S(=O)(=O)C(F)(F)F)CC1 +CCOCc1ccccc1CNC(=O)c1cc(C)nn1C +CCCN(CC1CC1)C(=O)CSc1ccccc1 +Cc1cc(Oc2cncc(C(N)=O)c2)c(C#N)c(C)n1 +COc1cc(C(=O)Nc2c(C)cc(C)nc2C)cc2c1OCCO2 +COc1cccc(C(=O)Nc2ccc(NC(C)(C)CO)nc2)c1 +Cn1cc(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)ccc1=O +CS(=O)(=O)c1ccc(F)c(NC(=O)NCCO)c1 +O=C(C1COc2ccccc2O1)N(Cc1ccccc1)c1ccccn1 +C=CCN(CC=C)C(=O)c1ccc(NC(=O)c2ccc(C)nc2)cc1 +O=C(CCc1ccco1)N1CCCC1c1nc2ccccc2s1 +COC(=O)C1(NCc2ccc(Br)c3cccnc23)CC1 +O=C(Nc1cccc2ccccc12)c1csnn1 +N#Cc1nc(C2CC2)oc1N1CCN(C(=O)c2cnns2)CC1 +COc1ccc(CNC(=O)c2ccnc3ccccc23)cc1O +CCCNC(=O)c1cccc(C(=O)Nc2ccc(C(C)=O)c(C)c2)c1 +Cc1ccc(F)cc1-n1ccn(CC#N)c(=O)c1=O +CCC(Cc1ccc(C)cc1)NC(=O)c1c(C)cc(C)[nH]c1=O +Cc1n[nH]c(-c2cccc(CNC(=O)c3ccc(F)c(Cl)c3)c2)n1 +CN(C)C(=O)c1cccnc1-c1cc(F)cc(F)c1 +CC1CCN(C(=O)CCc2nc(C3CC3)no2)C(C)C1 +CC(c1ccccc1)N(C)C(=O)c1cccc(N2CCCC2=O)c1 +Cc1ccc(C)c(NC(=O)NC(C)C(=O)N2CCCCC2)c1 +CCOc1ccc(CC(=O)Nc2sc(C)c(C)c2C(=O)OC)cc1 +CCC(CC)(CO)Nc1cc2ccccc2c(=O)[nH]1 +O=C(COc1cccnc1)NCc1ccc2sccc2c1 +COC(=O)Nc1cccc(NC(=O)CSc2ccccc2)c1 +Cn1c(C(=O)Nc2ccon2)cc2c(=O)n3ccccc3nc21 +CCC(CC)c1c(C#N)nnn1Cc1ccccc1 +CC(C)Oc1ncc(C(=O)NC(C#N)c2ccccc2F)cc1Cl +CN(CCOCC1CC1)Cc1ccc(C#N)cc1F +O=C(NCC1CCN(C(=O)Oc2ccccc2)CC1)c1ccccn1 +CC(=O)Nc1cccc(NC(=O)C(C)Sc2ccccn2)c1C +Cc1nc(C)c(CNCC2(c3ccc(F)cc3F)CC2)s1 +CCCN1C(=O)c2ccccc2NC1c1ccc(-n2ccnc2)cc1 +CCS(=O)(=O)N1CCCc2cc(NC(=O)c3cnoc3C)ccc21 +COC(=O)c1cccc2c1CCCN2CC(=O)N(C)C +Cc1cc(NS(=O)(=O)c2c(C)n[nH]c2C)ccc1N1CCCC1=O +O=C(Nc1cccnc1)c1cc(Cl)ccc1Cl +CCNC(=O)c1ccc(CNC(=O)c2ccnc3ccccc23)cc1 +COc1ccc(COCC(=O)N2CCCC2c2cnn(C)c2)cc1 +Cc1cc(C(=O)N(C)Cc2ccc(F)cc2)c2c(C)noc2n1 +Cc1noc(C(C)N2CCN(CC(=O)NC(C)c3ccco3)CC2)n1 +CC(=O)N1CCN(C(=O)C(C)Cc2ccccc2)CC1 +CCc1noc(CC)c1CC(=O)NC1CCCOc2ccccc21 +CC(=O)Nc1ccc2c(c1)C(Cc1cccc(O)c1)NCC2 +N#CCOc1cccc(CC(=O)NCC(=O)Nc2cccnc2)c1 +Cc1c(C(=O)NC(C)C(C)(C)C)nnn1-c1ccc2ncccc2c1 +Cc1nn(C)cc1C(C)NC(=O)c1cn2cccc(C)c2n1 +COc1ccc(C)cc1NC(=O)c1cc(C)n2nccc2n1 +Cc1nnc2ccc(C(=O)NCCc3cccc4cccnc34)cn12 +Cc1nc(SCC(=O)N2CCC(C)CC2)c2ccsc2n1 +COC(=O)C1CCCN1C(=O)c1ccc(C)c(F)c1 +CCc1ccc(NC(=O)CC(F)(F)F)cc1S(N)(=O)=O +CCC(CC)c1nnc(NC(=O)Cc2ccc(F)cc2F)s1 +CS(=O)(=O)c1ccc(OC2CCOC2=O)cc1 +CC(C)(CNS(=O)(=O)c1ccc(F)cc1)NS(C)(=O)=O +CC(C)(C)c1nc(C(C)(C)NC(=O)c2ccccc2)no1 +CCNc1sc2c(c1C(=O)NCCCOC)CCCC2 +CSc1nnc(SCc2cccc(C(=O)N(C)C)c2)s1 +Cc1cc(NC(=O)c2ccc(C)c(NC(=O)c3ccccc3)c2)ccn1 +CCCn1nccc1NC(=O)c1cc2ccc(C)cc2[nH]1 +Cc1nn(C(F)F)c(C)c1S(=O)(=O)N1CCC(C)CC1 +CC(C)NC(=O)c1ccccc1S(=O)(=O)N(C)c1ccccc1 +CC(=O)c1cccc(NC(=O)CCCC(O)c2ccccc2)c1 +CCCCC(NC(N)=O)C(=O)N1Cc2ccccc2N(C)CC1CC +CCNC(=O)NCC1CCN(C(=O)c2ccccc2F)CC1 +COc1cc(NCc2cc3n(n2)CCCN(C(C)=O)C3)ncn1 +Cc1ccc(OCCNC(=O)CNC(=O)c2ccccc2C)cc1 +O=C(N=c1[nH]ccn1Cc1ccc(Br)cc1)c1ccn[nH]1 +Cc1ccccc1C1CC1C(=O)OCCNS(C)(=O)=O +CS(=O)(=O)c1cccnc1C1CCN(C(=O)c2ccncc2)CC1 +Cc1nc(SCC(=O)N(C)C2CCCCC2C)oc1C +CCOC(=O)Nc1ccc2c(c1)C(=O)Nc1ccccc1O2 +Cc1ccccc1COc1cccc(NC(=O)C(C)NC(N)=O)c1 +CN(C(=O)c1cc(S(=O)(=O)N(C)C2CC2)c[nH]1)C1CC1 +CC(C)Oc1ccc(CNC(=O)c2cc(-c3cccnc3)[nH]n2)cc1 +CCCc1ncc(C(=O)NCc2ccc(OC)cc2)c(N)n1 +Cc1n[nH]c(C)c1NC(=O)c1ccc2c(c1)CCO2 +Cc1nc(N2CCCC2)nc2c1CCN(C(=O)N(C)C)CC2 +CCOc1ccc(S(=O)(=O)NC(CC)CO)c(C)c1C +Cc1ccc(N(C)C(=O)c2ccnc(F)c2)c(C)c1 +COc1ccc(F)cc1C(=O)c1csc(N(C)C)n1 +CCc1nnc(COC(=O)c2nc(-c3ccccc3)oc2C)o1 +Cc1ccc(C)c(SCC(=O)NC2CCCNC2=O)c1 +CN(CCCCc1ccccc1)C(=O)Nc1cn[nH]c1 +CCOc1ccc(C(C)NC(=O)NC(C)c2nncn2C)cc1OC +NC(=O)c1ccc(OS(=O)(=O)c2ccc3c(c2)CCCC3)cc1 +CCOC(=O)CC(NC(=O)c1cccc(C)c1)c1ccc(C)cc1 +Nc1ccc(S(N)(=O)=O)cc1Br +COc1cc(C(=O)N(C)Cc2ccc(C)o2)cc(OC)c1C +Cc1cc(C)c(C)c(OCC(=O)NC2CCOCC2)c1 +COCc1ccc(C(=O)N2CCC(Oc3ncccn3)CC2)s1 +CN(Cc1ccc(C(N)=O)cc1)Cc1cccs1 +Cc1cc(N(C)C)cc(C)c1NC(=O)N1CCc2cc(F)ccc2C1 +Cc1cnccc1Cn1ccc(-c2cccc(-c3nccn3C)c2)n1 +COc1cc(CN2CCOCC2)cc(Br)c1O +O=C(C1CCCCC1)N(Cc1cccnc1)C1CC1 +CCN1C(=O)C(C)Nc2cc(Br)ccc21 +O=C(NCCn1ncccc1=O)c1cncc(Br)c1 +COc1ccc(C(=O)NCCCc2cnn(C)c2)c(O)c1 +CCc1c(-c2ccncc2)n[nH]c1NC(=O)c1nccnc1N +Cn1cnnc1C1CCN(C(=O)c2ccc(-n3cccc3)cc2)CC1 +O=C(Cc1cnn(-c2ccccc2)n1)N(C1CCCC1)C1CC1 +COc1cc(C)c(C(O)CNC(=O)c2ccccc2C)cc1C +Cc1ccoc1C(=O)OCCn1cc(Br)ccc1=O +CC(C)(C)N1CC(C(=O)Nc2cccc(C(F)(F)F)c2)CC1=O +N#Cc1cn2cc(Br)cc(Cl)c2n1 +CCOc1ncccc1NC(=O)N1CCc2ccccc2C1 +COC(=O)CCNC(=O)Cn1c(=O)oc2ccccc21 +CCCNS(=O)(=O)c1ccc2c(c1)N(C(C)=O)CCS2 +CCC1c2ccccc2CCN1C(=O)C1COc2ccccc2O1 +CSc1nc(C)c(CCC(=O)N(C)CC(=O)N(C)C)c(C)n1 +C=C(C)CN(CC)C(=O)Nc1cnn(-c2ccccc2)c1 +COC(=O)C1CCCCC1OC(=O)c1cnn(C(C)(C)C)c1 +C#CCNC(=O)NC1CCCOc2cc(F)ccc21 +Cc1cc(C)cc(-n2ccc3nc(N4CCOCC4)ncc3c2=O)c1 +Cc1cccc2c1N(C(=O)c1ccnc(-n3ccnc3)c1)CC2 +OCc1ccc(-c2cccc(Br)c2)nc1 +C=CCN1CCN(C(=O)COc2ccccc2C(C)C)CC1 +O=C(Cc1cccs1)N1CCC2(CCCN(c3ncccn3)C2)C1 +COCCN(Cc1ccc(C#N)cc1)C(=O)c1cnn(C(C)(C)C)c1 +CC(C)Sc1nnc(-c2ccc(F)cc2)n1N +C#CCNCc1cc(Cl)cc(OC)c1OCC +COc1ncccc1CNC(=O)c1cc(-c2ccccc2)on1 +CCn1ccc(C(=O)Nc2cc(C(=O)OC)cc(C(=O)OC)c2)n1 +CNC(=O)COC(=O)C1(c2ccc(C(C)(C)C)cc2)CC1 +Cc1ccnc(SCc2cn3cccnc3n2)n1 +CC(=O)Nc1ccc(-n2cc(CCO)cn2)c2cccnc12 +CSc1nc2nc(C)c(CC(=O)N3CCCCC3C)c(C)n2n1 +CCn1cc(S(=O)(=O)Nc2ccccc2C)c(N)n1 +Cc1cc(C)n(-c2ccc(NC(=O)NCc3ccc(F)cc3)cn2)n1 +CCc1nc2n(n1)CCCC2NC(=O)c1sccc1CC +O=C(Nc1ccccc1)Nc1ccc(S(=O)(=O)N2CCCC2)cc1 +Cc1ccc(-n2cnnc2SCC(=O)OC(C)C)cc1C +CCCOC1CCCN(c2c(N)cccc2Cl)C1 +CC(Cc1ccccc1F)NC(=O)c1ccc(-n2cncn2)nc1 +COCC(NC(=O)N1CCc2ccc(Cl)cc2C1)C1CC1 +O=C(C1CCCN(c2nc3ccc(F)cc3s2)C1)N1CCOCC1 +O=C1CN(c2ccc(OC(F)(F)F)cc2)C(=O)CN1CC1CC1 +CCC(NC(=O)N1CCOCC1C1CC1)c1ccc(Cl)cc1 +CC(=O)NC(CC(=O)NCc1ccc(Cl)cc1)c1cccs1 +CCN(CC)S(=O)(=O)N1CCN(Cc2nc(N)nc(N)n2)CC1 +CCC(C)(C)NC(=O)NCCc1cccc(C(=O)OC)c1 +Cc1cc2ncc(C(=O)N3CCN(Cc4ccccc4)CC3)c(C)n2n1 +CCS(=O)(=O)N1CCC(C(=O)c2cc(C)ccc2C)CC1 +CSc1cccc(NC(=O)COCC2CCCO2)c1 +Cc1[nH]c2ccccc2c1-c1csc(N2CCOCC2)n1 +Cc1cc(=O)n(C)cc1NC(=O)c1ccc(C(F)(F)F)cc1 +COc1ccc(Nc2ncnc(-n3nnc4ccccc43)c2N)cc1 +CCC(C)N(CCOC)Cc1nc2c(cnn2C)c(=O)[nH]1 +Cc1ccccc1CN(C)S(=O)(=O)Cc1ccon1 +CC(C)NC(=O)c1nc2ccccn2c1-c1ccsc1 +COc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)cc(C)c3c2)cc1 +Cc1ccc2sc(-c3ccc(N)cc3O)nc2c1 +Cc1cc(F)ccc1S(=O)(=O)NCC1CC(=O)Nc2ccccc21 +Cc1nn(C)c2c(N3CCCC3)nc(C3CC3)nc12 +COc1ccc(Cc2nc(C)c(C#N)s2)cc1OC +C=CCOc1cccc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1 +CCCc1ccc(C(=O)N2CCC3C2CC(=O)N3CCOC)cc1 +CCOC(=O)c1[nH]c(C)c(C(=O)Nc2cccc(OC)c2)c1CC +Cc1ccc(CC(=O)NCc2ccc(C#N)cc2)cn1 +Cc1nc(CN2CCN(Cc3cnc(C4CCC4)s3)CC2)no1 +CCCN(CC(=O)Nc1ncc(C)s1)C(=O)C1CCCC1 +CCC1CN(S(C)(=O)=O)CCC1NC(C)C(=O)N(CC)CC +CN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1Cl +Cc1oc2nc[nH]c(=O)c2c1C(=O)Nc1ccc(F)cc1 +CCC1C(=O)NCCN1Cc1cnc(-c2ccc(C)o2)s1 +CC(CO)N(C)C(=O)NC(c1c(F)cccc1F)C(F)(F)F +CCC(C)(COc1nn2ncnc2cc1C)CS(N)(=O)=O +O=C(CCC(=O)c1ccc2c(c1)OCCO2)OCC(F)(F)F +CN1C(=O)C2(CCCN(C(=O)c3cc(O)n[nH]3)C2)c2ccccc21 +CC1NCCc2cc(Br)cc(Cl)c21 +COc1ccc(OC)c(NCc2ccc(C#N)cc2)c1 +CCOc1ccc(SCC(=O)NC(C)CC)cc1 +C=CCNC(=O)c1ccc(NC(=O)c2cn(-c3ccccc3)nn2)cc1 +CCNS(=O)(=O)C1CCN(C(=O)c2cc3ccccc3cc2O)C1 +COc1cc2c3c(c1OC)C(=O)CC3N(C(=O)C(C)C)CC2 +CC1Oc2ccc(C(N)C(F)(F)F)cc2N(CCO)C1=O +Cc1c(C(=O)N2CCCCC2)nnc2c(-c3ccccc3)cnn12 +CCC(CC)N(CCO)C(=O)c1ccc(NC)nn1 +CCOC(=O)c1ccc(OC)c(S(=O)(=O)NC(C)C)c1 +Fc1cc(Br)ccc1CN1CCOCC1C1CC1 +COc1ccc(CCC2CCCN(S(C)(=O)=O)C2)cc1 +CCSc1ccc(NC(=O)CCc2ccsc2)cn1 +CCC(=O)N1CCN(Cc2c[nH]nc2-c2cccc(Cl)c2)CC1 +COc1ccccc1C(C)NCCN1CCOCC1 +Cc1cccc(C)c1NC(=O)C1CC(=O)Nc2ccccc21 +CCOc1cccc(NC(=O)NC(C)C(C)C)c1 +CC(=O)c1ccc(N2CCC(OC(=O)CC3CCCO3)CC2)cc1 +CC1CCCCN1C(=O)c1cc2c(nc1N)CCCCC2 +C=CCOCC1CCCC12CN(Cc1nccs1)CCO2 +Cn1nnc2c(N3CC(C(=O)Nc4ccccc4Cl)C3)ncnc21 +COc1ccc(CC2=C(Nc3ccc4c(c3)OCO4)COC2=O)cc1 +CC(C)N(CCO)C(=O)c1cnn2c1OCCC2 +CN1CC(C(=O)NCc2ccccc2CN2CCCC2=O)CC1=O +C=CCNC(=O)c1ccc(N(C)S(C)(=O)=O)c(C)c1 +Cc1ccc(NC(=O)C2CCCN(C(=O)NC3CC3)C2)cc1C +O=C(CN1CCc2ccc(Cl)cc2C1)NC1CCCC1 +CCOc1ccccc1-c1nc2cccc(C)n2c1CO +COCC(C)NC(=O)NC1CC(=O)N(c2ccc(OC)cc2)C1 +CC(C)NC(=O)COC(=O)c1cc(Br)ccc1O +Cc1c(C2CC(C(F)(F)F)n3nccc3N2)cnn1C +CCn1nccc1C(=O)Nc1nc(-c2ccncc2)cs1 +COCC(C)NC(=O)N1CCN(CC(=O)NC(C)C)CC1 +O=C(CN1C(=O)c2ccccc2S1(=O)=O)Nc1cccc(O)c1 +COc1ccc(OCCCn2nnc(C#N)c2C2CC2)cc1 +CC(NC(=O)N(C)C(C)c1ccncc1)C(=O)N(C)C +Cn1c(=O)cc(C(=O)NCCc2ccccn2)c2ccccc21 +CCC1CCc2c(sc3nc(CCCOC)[nH]c(=O)c23)C1 +O=C(Cc1ccccc1)NCC(O)c1ccc2c(c1)OCO2 +CCOC(=O)c1snnc1-c1ccc(F)cc1 +CC(C)C(NC(=O)c1ccco1)C(=O)N(C)Cc1cccnc1 +O=C1Nc2ccccc2CCC1Sc1nnc(-c2ccncc2)o1 +CC(=O)NCC1(c2cccc(Br)c2)CCOCC1 +O=C(c1csc(-c2cnccn2)n1)N1CCCC1C1CCCCC1 +CC(C)n1cc(-c2cc3n(n2)CCC(=O)N3)c2ccccc21 +COc1ccccc1-c1nnn(-c2cccc(O)c2)c1N +CSc1ccc(C(=O)N2CCOCC2c2c(C)nn(C)c2C)o1 +Cc1ccc(O)c(C2C3=C(COC3=O)Nc3[nH]nc(C)c32)c1 +O=C1CCOCCN1Cc1ccc(OC(F)F)cc1 +Cc1noc(C)c1CCCNC(=O)NC1C2CCOC2C1(C)C +CCn1ccnc1SCC(=O)c1cnn(C)c1 +COc1ccc(CCC(=O)NCCC(C)C)cc1N +CC(C)(C)c1nc(C(=O)NCc2noc(-c3ccco3)n2)cs1 +COc1cc2[nH]c3c(=O)n(Cc4ccncc4)cnc3c2cc1OC +C=CCn1c(C)nnc1SC(C(=O)OC)c1ccccc1 +O=C(NCc1ccccc1)c1ccccc1NC(=O)C1CC1 +CN(C)S(=O)(=O)c1ccc(OC(=O)c2ccsc2)cc1 +Cc1noc(C(C)NC(=O)NC(c2ccccc2)c2nccn2C)n1 +CC1CC(OC(=O)CNC(=O)CC23CC4CC(CC(C4)C2)C3)C(=O)O1 +COC(=O)c1cc(=O)c2c(Br)ccc(C)c2[nH]1 +CN(C1CCN(C(=O)c2cc(Cl)ccc2O)CC1)S(C)(=O)=O +Cc1nc2sccc2c(=O)n1NC(=O)C(C)OCC1CCCO1 +CCC1CCCCC1NC(=O)c1cc(N)c(C)s1 +CC(=O)Nc1nc(C(=O)NCC(O)COc2ccccc2)cs1 +Cc1nc(COc2ccc(F)cc2)sc1C(=O)N1CCC(C)CC1 +CC(C)c1nc(C2CCCN2C(=O)c2cccc3c2ccn3C)no1 +CN(C)C(=O)CCNS(=O)(=O)c1cccc(Br)c1 +CCOCCSc1nc2ccccc2n1CC +CC(C)n1c(SCCn2c(=O)oc3cccnc32)nnc1N(C)C +Cc1nn(C)cc1-c1cc(C(=O)NCCn2nc(C)c(C)c2C)on1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)NCc2cnc(C)s2)c1 +CCC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCCCC2)c1 +O=C(NCc1ccc(F)cc1)C1(n2cnnn2)CCCCC1 +COc1ccccc1CNC(=O)c1cn(-c2ccc(C)cc2)nn1 +Cc1c(C(=O)NCc2cccc(NC(=O)c3ccccn3)c2)cnn1C +COCC1(C(=O)NCc2ccc(Cl)c(Cl)c2)CCC1 +Cc1cc(OCC(=O)N2CCCC(n3cncn3)C2)no1 +Cc1noc(C)c1CC(=O)OC(C)c1c(F)cccc1N(C)C +Cc1[nH]c2ccc(Br)cc2c(=O)c1C(C)C +CC(C(=O)N1CCc2sccc2C1)N1CCOC(C(N)=O)C1 +Cc1ccc(-c2nnco2)cc1NC(=O)NCC(=O)N1CCCCC1 +CCCNC(=O)NCCc1ccc(S(N)(=O)=O)s1 +COc1cccc2c1NC(=O)CC2C(=O)NCc1ccncc1 +CCOc1cc(C(=O)NC(C)(C)CC)ccc1OC +COc1cc(C)c(C)cc1C(=O)CCCC(=O)N1CCCC1 +Cc1nn(C)c2ncc(NC(=O)CCc3ccsc3)cc12 +O=C(CC1CC(=O)Oc2ccccc21)Nc1nc2ccccc2s1 +Cc1cc(CN2CCC3(C2)OCCO3)ccc1-n1cncn1 +C=CCNC(=O)NCC1CCN(C(=O)Nc2ccc(F)cc2)CC1 +O=C(CCc1cccnc1)NC1(c2ccc(F)cc2F)CCOCC1 +Nc1cccc(CCC(=O)NCCS(N)(=O)=O)c1 +O=C(Cc1ccc[nH]1)Nc1cc(Cl)ccc1C(=O)N1CCCCC1 +CCN(C(=O)c1cccc(NCC(=O)N(C)C)c1)c1ccccc1 +Nc1nc(SCc2csc(-c3ccc(F)cc3)n2)n[nH]1 +CC(CCN1CCOCC1)NC(=O)Cc1noc2ccccc12 +O=C(c1n[nH]c2ccccc12)N1CCN(Cc2ccon2)CC1 +CN(C)C(=O)CCc1ccc(NC(=O)c2cccnc2)cc1 +Cc1cccc(NS(=O)(=O)c2cccc(C(=O)NC3CC3)c2)c1 +CCCC1CN(C(C)=O)CC1NC(=O)C1CCCCCC1 +CC(=O)c1ccc(C(=O)NCCCc2cnn(C)c2)cc1 +COCc1ccc(C(=O)N(C)C(C)c2ccc(F)c(F)c2)o1 +CCOC(=O)CC(C)CNC(=O)NC1CCCC1(C)C +Cc1cc(NC(=O)C2CC2)sc1C(=O)N1CCCCC1C +O=C(COc1ccc(NC(=O)C2CC2)cn1)NC1CCCC1 +CC(C)C(C)NS(=O)(=O)c1ccc(Cl)cc1 +O=C(Cc1cc(-c2ccco2)on1)NCCc1c[nH]c2ccccc12 +CCCN(C(=O)c1cc(=O)c(OC)c[nH]1)C1Cc2ccccc2C1 +CCOc1ccc(CN2CCN(C(=O)c3ccsc3)CC2)cn1 +CC(C)c1ncc(Cl)c(C(=O)Nc2nc3ccc(F)cn3n2)n1 +Cn1cnc(CNS(=O)(=O)c2ccccc2C#N)n1 +CC(C)=CCC1(CO)CCCN(c2nccnc2C)C1 +O=C(Cc1noc2ccccc12)NC1CCCc2ccccc21 +Nc1c(Nc2cccnc2)ncnc1Nc1nc2ccccc2s1 +CCCNc1ccc(C(=O)NCC(=O)NCC)cc1 +O=C(NCc1cc2ccccc2o1)c1ccc(C(F)(F)F)nc1 +COC(=O)c1nsc(C(=O)Nc2cccc(C)n2)c1N +O=C(NCCc1cn2ccccc2n1)c1cnc(C2CCCO2)s1 +CC(OC(=O)c1cccc(S(C)(=O)=O)c1)C(=O)N1CCCC1 +COc1cc2c(cc1OC)CN(C(=O)c1ccc3[nH]cnc3c1)CC2 +Cc1ccc(C)c(NC(=O)C(C)N2CC(C)Oc3ccc(N)cc32)c1 +Cc1c(C#N)c2ccccc2n1CC(=O)NCc1ccco1 +COc1cc(C)sc1C(=O)NC1CCN(c2ccccc2)C1 +Cc1nc(NCc2c(C)n[nH]c2C)c2cnn(C)c2n1 +CS(=O)(=O)NCCNC(=O)c1ccc2c3c(cccc13)CC2 +Cc1ocnc1CNC(=O)Nc1ccc(F)c(F)c1F +O=S(=O)(NCCCn1cccn1)c1c(Cl)cccc1Cl +Nc1cccc(-c2nc3cc(C(F)(F)F)ccc3[nH]2)c1 +FC(F)(Br)C1=NCCN1Cc1ccccc1 +CCn1nc(C)c(CCNC(=O)NCc2ccccc2)c1C +CC1CCN(C(=O)C2CSc3nccc(=O)n3C2)CC1 +CC(CCCO)NC(=O)N1CCN(CC(=O)N2CCCCC2)CC1 +Cc1nc(SCC(=O)NC(C#N)C(C)(C)C)c(C#N)c(C)c1C +CCOc1ncnc2c1CN(Cc1c(C)noc1C)CC2 +OCc1ccc(Oc2cccc(C(F)(F)F)n2)cc1 +COCC(C)N(C)C(=O)c1cc(-c2ccc(C)s2)[nH]n1 +CCc1noc(CSc2ncc(Cl)cc2Cl)n1 +CCn1c(C(=O)NCCCOC)cc2sccc21 +COCCCNC(=O)Cn1nc(-c2ccccc2)ccc1=O +Cc1noc(C)c1CC(=O)OCCOc1cccc(Cl)c1 +CCn1c(CCNC(=O)c2ccc(C)s2)nc2cccnc21 +CCOc1ccccc1NC(=O)c1cccnc1OCC +COc1cc(C)cc(C)c1CCCn1cc(N)cn1 +Cc1c(C(=O)N(C)CC(=O)N(C)C)oc2c(Cl)cccc12 +C=CCNC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1 +Cn1c(=O)c2c(SCc3ccc(F)cc3)ccnc2n(C)c1=O +Cc1c(NS(C)(=O)=O)cccc1C(=O)NC(C)c1ccccc1 +CCS(=O)(=O)c1ccc2[nH]c(=O)cc(C)c2c1 +Cc1ccc(-c2cc(C(=O)Nc3c(C)n[nH]c3C)[nH]n2)cc1 +CC(C)N(CC1CCCCCC1=O)CC(F)(F)F +CCOc1ccccc1C(=O)NCCCS(N)(=O)=O +COc1c(O)ccc2c1C(c1cccc(C)n1)NCC2 +Cc1nccc(N2CCCC(N(C)C(=O)OC(C)(C)C)C2)n1 +O=S(=O)(c1cc2ccccc2s1)N1CCCC(O)(CO)CC1 +CCc1nnc(NC(=O)C2(C)Oc3ccccc3NC2=O)s1 +CCC(O)CN1CCN(C(=O)COCC(F)(F)F)CC1 +CCc1nnc(CN(C)c2nc(C(C)C)nc3c2cnn3C)o1 +CCC(C)NC(=O)Cc1noc2c(C)c(C)c(N)cc12 +COCC(NC(=O)CC(C)c1ccccc1)C(N)=O +CC(OC(=O)c1cc2ccccc2o1)C(=O)NC(C)(C#N)C(C)C +Cc1cccnc1NC(=O)c1ccc2c(c1)OCCCO2 +COC(=O)CCCNC(=O)C1CC(=O)N(c2ccc3c(c2)CCC3)C1 +Cc1ocnc1CNC(=O)Nc1ccccc1OC(F)F +Cc1sc(NC(=O)C2CC2)c(C(=O)N2CC3CCCC3C2)c1C +CC1CCN(S(=O)(=O)c2ccc(S(N)(=O)=O)cc2)CC1 +CC(C)OCCS(=O)(=O)NCc1cccc(Br)c1 +CCc1noc(CC)c1CC(=O)NCc1cc(F)cc2c1OCOC2 +CCC(=O)Nc1ccc2c(c1)N(S(=O)(=O)c1ccccc1)CCC2 +CCn1c(C2CCN(C(=O)CCNS(C)(=O)=O)CC2)n[nH]c1=O +CCCn1c(C)nnc1SCC(=O)c1cc(C)n(C2CC2)c1C +O=C(c1cccnc1)N1CCCC1Cc1ccccc1 +Cc1c(C(=O)NCC(C)C)sc2ncnc(NCC3CCCO3)c12 +CCOc1ccc(F)c(C(=O)NC(C)C2CCOC2)c1F +CCC(C)N(C)C(=O)Nc1cc(OC)c(OC)c(OC)c1 +C#Cc1cccc(NC(=O)c2cccc(-n3cnnn3)c2)c1 +CCCOc1ccc(-c2nc3scc(N)n3n2)cc1 +CCc1nnc(NC(=O)NCCc2cnn(-c3ccccc3)c2)s1 +CCN1C(=O)CCc2cc(NC(=O)C3CCC3)ccc21 +CCc1nc(CNc2ccc(Cl)cc2F)cs1 +O=C(CSc1nn2cnnc2s1)Nc1ccccc1 +CC(NC(=O)c1ccccn1)c1ccc(NC(N)=O)cc1 +CS(=O)(=O)c1ccc(C(=O)OCC2CC2(Cl)Cl)cc1 +Cc1csc(=O)n1CCC(=O)NC(C)c1cc2ccccc2o1 +Cc1nc(CCNC(=O)Cc2c(F)cccc2Cl)cs1 +COc1ccccc1CNC(=O)c1cn[nH]c1-c1ccc(Cl)cc1 +CCCC1CN(C(=O)C2(CCOC)CCCC2)CCO1 +CC(=O)N1CCN(C(=O)CN2CC(c3ccccc3)OCC2C)CC1 +CC(C)(C)C(NC(=O)COc1ccc(F)c(Cl)c1)C(N)=O +O=C(NCc1ccc(=O)[nH]c1)C1(c2ccccc2)CCOCC1 +CCC(=O)c1cccc(S(=O)(=O)NCC(C)(C)c2ccncc2)c1 +Cc1nnc(CNC(CC2CCC2)c2ccccc2)s1 +CN(C)C(=O)COCc1cncc2c1CCN(C1CCOC1)C2 +CC(C)CNC(=O)CSc1nnc(-c2ccccc2)o1 +Cc1ncsc1CCCNC(=O)Cn1cnc2ccccc2c1=O +Nc1cccc(C(=O)c2cc(C(F)(F)F)ccc2O)c1 +CC(C)(C)c1noc(CCc2nc(-c3ccc(C#N)cn3)no2)n1 +CC(=O)NC(C(=O)N(C)Cc1c(C)noc1C)C1CCCC1 +CNC(=O)c1cn(Cc2ccccc2)nc1-c1ccc(Cl)cc1 +COc1ccc2oc(-c3ccc(N)cc3O)nc2c1 +COC(=O)c1ccc(C)c(NCC(=O)Nc2ccccc2C#N)c1 +Cc1ccc(OCCNC(=O)c2cccc(C3OCCO3)c2)cc1 +Cc1sc2ncn(Cc3cnn(C)c3C)c(=O)c2c1C +COCCn1ccc2cc(NC(=O)c3cccnc3)ccc21 +CC1(C)Cc2cccc(OCC(=O)N3CCNC(=O)C3)c2O1 +CC(C)(CO)Nc1ncc(Br)c2ccccc12 +Cc1ccc(-c2cc(C(=O)NCc3nnc4n3CCCCC4)[nH]n2)o1 +COc1cccc(CN2CC(C(=O)Nc3ccccc3F)CC2=O)c1 +CCCc1nn(-c2ccccc2C(=O)OC)c2c1CN(C)CC2 +COCCNc1ncc(-c2onc(C)c2C)c(-c2ccco2)n1 +CC(=O)N1CCN(C(=O)c2cnn3c(C)cc(C)nc23)CC1 +COc1ccc(C(=O)NCC(=O)Nc2ccc(Cl)cc2C)cc1 +COc1ccccc1NCc1cc(OC)c(O)c(OC)c1 +Cc1cc(C(=O)N2CCN(C(=O)c3cc[nH]c3)CC2)on1 +Cc1csc(NC(=O)c2cc(Cl)ccc2F)n1 +COCC(=O)NCc1ccc(-c2nc3ccccc3s2)o1 +CCOC(=O)c1sc(NC(=O)c2ccc(=O)[nH]c2)nc1C +Cc1noc(C2CC2)c1C(=O)Nc1cc(-c2cccs2)n[nH]1 +Cc1ccc(C(=O)N(C)Cc2ccc3c(c2)OCCO3)c(O)c1 +Cn1ncc2c1CCCC2NC(=O)NCc1ccc2c(c1)CCC2 +COc1cc(-c2noc(CN(C)S(C)(=O)=O)n2)ccn1 +CCOc1ccc(S(=O)(=O)NCCO)cc1C +CC(NC(=O)CNC(=O)OC(C)(C)C)c1ccc2c(c1)OCCO2 +CCOC(=O)c1c(-c2cc(C)ccc2F)n[nH]c1N +CCCOc1ccc(CNC(=O)C(C)c2ccsc2)cc1 +CC(C)(C)c1ccc(COC(=O)c2nccnc2N)cc1 +CCOCc1ncn2c1CN(C(=O)Nc1cccc(F)c1)CC2 +NC(=O)c1ccc(N2CCc3c(N)cccc3C2)cc1 +O=S1(=O)COCCN1Cc1noc(-c2ccccc2)n1 +COCC12CCC(N3CCOCC3)CC1CCN(Cc1cnc[nH]1)C2 +COCc1cccc(C(=O)N2CCOCC2(C)C)c1 +OCc1c(-c2ccccn2)nc2c(Cl)cc(Cl)cn12 +COC(=O)c1cccc(NC(=O)c2nnn(-c3ccccc3)c2C)c1 +CN(Cc1ccco1)C(=O)CSc1nc2cc(Cl)ccc2o1 +CCc1cc(OC(=O)Cn2ccc(=O)n(C)c2=O)ccc1Cl +CCOc1ccc(N(CC(=O)N2CCCC2)S(C)(=O)=O)cc1 +O=C(NCCc1ccc(C(F)(F)F)cc1)c1ccco1 +CC(=O)Nc1cccc(NCC(=O)c2c(C)cc(C)cc2C)c1 +COc1ccccc1-c1noc(CCCC(=O)NC(C)(C)C)n1 +Cc1cc(=O)n(CC(=O)Nc2cc(Cl)ccc2C#N)cn1 +CCN1CCN(C(=O)C(C)Nc2cccc(C(C)=O)c2)CC1 +Cc1[nH]c(=O)c(C(=O)NC(C#N)C(C)(C)C)cc1-c1ccccc1 +O=C(CSc1nnc(-c2ccco2)o1)Nc1ccccc1Cl +CCOC(=O)c1ccc(C(=O)Nc2nccs2)cc1 +COc1ccc(C(=O)N2CCCC2c2ccco2)cc1-c1ccccn1 +CCn1nnc2c1CCN(Cc1ccsc1)C2COCC1CC1 +CCOC(=O)C1CCN(C(=O)c2ccc3ccccc3c2O)CC1 +C#CCN1CCC(C(=O)Nc2ccc(C)cc2)CC1 +Cc1sc2nc(-c3cccs3)nc(-n3cnc(C#N)n3)c2c1C +O=C(c1cc(=O)[nH]c2ccccc12)N1CC=CC1CO +CCc1ccccc1NC(=O)c1nn(C)c2ccc(F)cc2c1=O +Cc1cccc(NC(=O)CSc2nnc(N)n2C)c1C +Cc1ccc(C(=O)NC2CC2)cc1Br +CC(=O)Nc1ccc(CNC(=O)c2ccc(OCC(N)=O)cc2)cc1 +Cc1cc(C(O)CNCc2ccccn2)ccc1Cl +Cc1ccc(NC(=O)c2ccncc2)cc1NC(=O)C1CC1 +O=C(NCC(CO)Cc1ccccn1)c1ccc(Br)cc1 +COCCCN(C)C(=O)Nc1ccc(Cl)cc1C +COc1ccc(Cc2noc(-c3ccc(CNC(C)=O)cc3)n2)cc1 +CC(C)C(=O)Nc1ccc(NCc2csnn2)cc1 +C=CCN(CCc1ccccc1)Cc1cn(C)nc1C +CCn1nc(C)cc1C(=O)Nc1sc2c(c1C(=O)OC)CCC2 +Cc1noc(C2CCCCN2C(=O)c2ccc3c(c2)OCCO3)n1 +CCOc1cc(S(=O)(=O)NCc2cccnc2)ccc1Cl +O=C(OCCc1c[nH]nc1C(F)(F)F)C1CCCc2ccccc21 +COc1ncccc1CNC(=O)c1cnn2cccnc12 +CNC(=O)c1ccc(OC2CC2)c(OC(C)(C)C)c1 +CCN(Cc1nc2cc(OC)c(OC)cc2c(=O)[nH]1)C(C)=O +COc1cc(OC)c(C#N)c(S(=O)Cc2ccccc2)c1 +COc1ccc(C(=O)N2CCN(CCO)CC2)cn1 +CN1CCN(C(=O)c2c(N)oc3ccc(O)cc23)CC1 +COc1ccc(OC)c(-c2cc(C(=O)Nc3ncc(C)s3)no2)c1 +CCC(C)(C)NC(=O)c1ccc(N2CCNC2=O)cc1 +OCC1(CC2CC2)CCCN(c2nc(-c3ccccc3)no2)C1 +COCCN(C)C(=O)c1cc2ccccc2c2cccnc12 +CS(=O)(=O)N1CCc2cc(C(=O)NCc3ccccn3)ccc21 +CSc1nsc(NC(=O)c2ccc(C)c(C)c2)n1 +CCOc1cccc(CN2CCOCC2CC)c1OC(F)F +CCOc1ccc(OCC(=O)Nc2ccccc2N(C)C)cc1 +COCCNC(=O)C1CCC(C)N(C(=O)c2ccc(C)c(F)c2)C1 +CN(CC1CC1)C(=O)C1CCCN1C(=O)C1CC1 +Cc1nn(C)c(C)c1OS(=O)(=O)c1cc(Cl)cc(Cl)c1 +Cc1noc(CCCC(=O)NCc2cnn(-c3ccccc3)c2)n1 +Cc1oncc1C(=O)N1CCn2c(-c3ccccc3)cnc2C1 +COCc1nn(Cc2ccc(OC(F)F)cc2)c(=O)o1 +Cc1cc(C)cc(N2CCC(NC(=O)c3cccc(C#N)c3)C2=O)c1 +CCCn1ncc(-c2ccnc(NC(CC)c3ccncc3)n2)c1C +CCc1ccc(S(=O)(=O)Nc2ccc(NC(=O)OC)cc2)cc1 +CC1CCN(C(=O)NCCC(=O)NC2CCCC2)C(C)C1 +CC1CCC(NC(=O)NCc2ncn(C)n2)CC1 +COc1cc(CNc2ncnc3[nH]cnc23)ccc1C +CCc1ccc(CNc2ncnc3ccc(F)cc23)s1 +Cc1cc(CNS(=O)(=O)c2c(C)noc2C)no1 +CC(CC(=O)NCc1cccc(NC(N)=O)c1)C1CC1 +CSc1cccc(CN(C)C(=O)c2ccccc2-c2nc[nH]n2)c1 +CCOc1ccccc1-n1nnc(CO)c1-c1cccs1 +CC(C)(C)OC(=O)N1CCCC1C(=O)NCCOc1ccccc1 +CCOC(=O)C(NC)c1cc(-c2nccn2C)ccc1F +CCS(=O)(=O)N1CCOC2CC(COc3ccccn3)CC21 +CCOC(=O)c1cncc(-c2cc(OCc3ccccc3)ncn2)c1 +CCCCNC(=O)CN1C(=O)COc2cc(O)ccc21 +Cc1ccc(S(=O)(=O)N2CCOc3ncc(C)cc32)c(C)c1 +COCCCC1CCCCN1C(=O)Cc1ccccc1 +Cc1cc(C(=O)NCc2ccnc(OC3CCC3)c2)c(C)n1C(C)C +Cc1cc(N2CCCC(c3cccc(C)n3)C2)ncn1 +CN(C)c1c(Cl)cccc1NC(=O)c1ccc(F)nc1 +O=C(NCc1nc(-c2cccs2)n[nH]1)C1(O)Cc2ccccc2C1 +Cc1ccc(OCc2nc(CC(=O)N3CCOCC3)cs2)cc1 +COc1ccccc1CC(=O)OCC1CCCCO1 +O=C(OCCNc1cccnn1)c1ccc2nncn2c1 +COc1ccc(NC(C)=O)cc1NC(=O)CSc1nccn1C +CCCn1cnnc1CNc1nc2c(s1)c(C)nn2C +Cc1ccc(C(=O)NCc2cccc3cccnc23)o1 +c1ccc(Cc2n[nH]c(CCc3ccc4c(c3)OCO4)n2)cc1 +COc1ccc(CC=Nc2cc3c(cc2C(C)=O)OCO3)cc1 +NC(=O)CSc1ccccc1NC(=O)Cc1c[nH]c2ccccc12 +COCc1ccc(C(=O)Nc2cccn(Cc3ccccc3)c2=O)o1 +Cn1cc(Br)cc1C(=O)Nc1cccc(CO)c1 +Cc1nn(C)c2nc(N3CCC(C)CC3)c(CO)cc12 +CC(=O)Nc1ccc(OCC(=O)NCc2ccc3c(c2)OCO3)cc1 +COC(=O)c1cc(COC(=O)c2ccc(C#N)cc2)oc1C +COc1ccccc1C(=O)N(C)Cc1ccc2c(c1)OCO2 +CN(Cc1ccc(S(C)=O)cc1)Cc1cnc(C2CCCC2)s1 +CCCc1cnc(C)nc1N1CCC(F)(F)CC1 +CC(C)CN(C)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +CCOC(=O)c1c(C)nc(N)nc1C(C)Oc1ccccc1OC +N#Cc1ccc(F)cc1CN(CC1CC1)CC(F)(F)F +O=C(CCN1CCCCC1=O)NC(c1ccccc1)C(F)(F)F +COC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(CO)cc1 +CC(c1ccncc1)N(C)C(=O)c1cccc(N)c1 +CSc1ncccc1C(=O)NC1CCCCCC1 +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)Nc1nccs1)O2 +CCCOC(=O)c1nnn(-c2ccc(C)cc2)c1C +CCc1cc(NC(=O)C2CCCCN2S(C)(=O)=O)[nH]n1 +CCC(=O)NCC(=O)Nc1ccc(-c2nnc3n2CCCC3)cc1 +CC(C)c1nnc(NC(=O)C2CC(=O)Nc3cc(F)ccc32)s1 +COC(=O)C(C)CNC(=O)Nc1ccc(-n2nc(C)cc2C)c(F)c1 +Cn1nncc1CN1CCN(C2c3ccccc3-c3ccccc32)CC1 +COC(=O)CNC(=O)c1cccc(OCc2ccccc2C#N)c1 +Cc1nc(CNC(C)Cc2cccc(F)c2)cs1 +CC(C(=O)N(C)CCC#N)N(C)Cc1ccccc1C(F)(F)F +Cn1cc(S(=O)(=O)Nc2ccn(Cc3cccc(F)c3)n2)cn1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3scnc3C3CC3)c2)n1 +CNc1nnc(-c2cnc(-c3ccccc3OC)s2)s1 +COc1ccc(C(=O)NCC(C)C)c(OC)c1OC +CCCN(CC#Cc1ccccc1)C(=O)c1cccnc1 +Cc1cc(CO)nn1-c1cccc(C(F)(F)F)c1 +CC(C)c1cc(C2CCCN2C(=O)c2ccnn2C)on1 +O=c1[nH]cnc2c1nc1c(Cl)cc(C(F)(F)F)cn12 +CCCCc1nnc(NC(=O)N2CCCC3CCCC32)s1 +CC(Nc1cccc(S(=O)(=O)N(C)C)c1)C1(C)CC1 +Cn1cccc1C(=O)Cn1cc(C(F)(F)F)ccc1=O +Cc1ccn(CC(=O)N2CCC3(CC2)CN(CCC(C)C)C(=O)O3)n1 +O=C(CCC1CCCO1)N(CCO)C1CCCC1 +Cc1cc(C)cc(NC(=O)CNC(=O)c2ccccc2)c1 +N#Cc1c(N)nc2c(c1-c1cnn(-c3ccccc3)c1)C1CCC(C2)N1 +Cn1cc(C(=O)N2CCN(c3ccc(F)cc3)CC2)c(C(C)(C)C)n1 +NC(=O)C1CCCCN1C(=O)CCc1cc(F)ccc1F +CNC(=O)CN1CCN(C(C)c2nc(-c3ccc(C)cc3)no2)CC1 +CN(Cc1ccnn1C)C(=O)Cn1nnc2ccccc21 +Cn1cc(C(=O)NCC(O)c2c(Cl)cccc2Cl)ccc1=O +Cc1ccc(NCc2nnc(SCC(N)=O)n2C)cc1 +COc1cc(N(C)c2cc(=O)n(C)c(=O)[nH]2)ccc1C +Cc1sc2nc(CCn3ccnn3)[nH]c(=O)c2c1C +N#Cc1ccccc1NC(=O)CN1C(=O)COc2ccccc21 +COc1ccc(CNc2ccc3c(c2)OCC(=O)N3C(C)C)cc1 +O=C(CCc1ccccc1)Nc1ccc(NC(=O)C2CCCO2)cc1 +COC(CNC(=O)C(C)NC(N)=O)c1ccccc1 +COC(=O)NCC(=O)N1CCCC1c1cccc(F)c1 +Cc1nc(CCn2ccccc2=O)n(CC(F)(F)F)n1 +CCC1COCCN1C(=O)Nc1cc(C)cc(C)n1 +NC(=O)c1cccc(CNCCc2cccc(F)c2)c1 +Cc1ccc(-c2cnn(CC(=O)Nc3ccc(F)cc3)c(=O)n2)cc1 +CCC(C)(C)NS(=O)(=O)c1ccc(OC)cc1 +COC(=O)c1c(C)oc2ccc(OCC(=O)C(C)(C)C)cc12 +COCC(O)CN(C)C(=O)Nc1ccc(OC2CCCC2)cc1 +CN(C(=O)NCCc1nnc2n1CCCCC2)C1CCCCC1 +Cc1cc(C)cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +CCCCC(=O)Nc1ccc(C(=O)Nc2nc(C)cc(C)n2)cc1 +COc1ccc(C)cc1C(=O)CCNc1ccc(C#N)cc1 +CCNC(=O)C(C)NC(=O)C1CC1c1ccco1 +CC1(C)Oc2ccc(S(=O)(=O)N3CCCC3)cc2NC1=O +COC(=O)CCCC(=O)N1CC(=O)N(c2cccc(OC)c2)C(C)C1 +COc1ccc(C)cc1NCC(=O)c1ccccc1 +Cc1cc2c(cc1CCOC(=O)CN)OCCO2 +Cc1cccc(N(C)C(=O)c2cccc3c2SCCC3=O)c1 +CC1CN(C(=O)CSc2nnc(-c3ccccc3)n2C)CC(C)O1 +Cn1ncc(NC2CCN(C(=O)c3ccccn3)C2)c(Cl)c1=O +OC(CNCc1ccccc1F)c1cc(F)ccc1F +CCc1[nH]nc(C(=O)Nc2c(C)nn(C)c2C)c1N +CS(=O)(=O)c1cccc(C(=O)Nc2nnc(-c3ccccc3)o2)c1 +COc1ncccc1NC(=O)N1CCC(Nc2ccc(F)cc2)CC1 +O=c1ccc(CNc2ccc(F)c(F)c2F)c[nH]1 +Cc1cc(CNC(=O)Cn2nnc(-c3ccccc3)n2)c(C)o1 +Cn1ccsc1=NC(=O)CCC1Cc2ccccc2NC1=O +Cn1cc(N2CCC(N3CCc4ccc(Cl)cc4C3)C2=O)cn1 +Cc1cc(C)n(-c2ncnc3c2oc2ccccc23)n1 +O=C(c1ccccc1NCc1ccc(F)cc1F)N1CCCCC1 +O=C(NCCc1ccccc1)c1nn(-c2ccccc2)c2c1COC2 +COc1ccc(-n2ccnc2SCc2n[nH]c(=O)[nH]2)cc1 +CC(NC(=O)c1ccc(F)cc1Cl)c1ccc(-n2cncn2)cc1 +CN(Cc1ccc(F)cc1)C(=O)c1sccc1-n1cccc1 +Cc1ccc(C(=O)Nc2cc3[nH]c(=O)[nH]c3cc2C)cc1 +CC(=O)NCC(=O)N(Cc1ccc(C(C)C)cc1)C1CC1 +CC(=O)N1CCCC(Cc2cc(Nc3cccc(C)n3)ncn2)C1 +COc1cc(CNC(=O)c2ccnc(-n3cncn3)c2)ccn1 +O=C(NCc1ccncc1)c1sccc1Br +CNS(=O)(=O)c1ccc(NC(=O)COc2cccc(C)c2)cc1 +N#Cc1ccccc1OCCN1CCNC(=O)CC1c1ccccc1 +Cc1nn2c(C#N)c(-c3ccc(Br)cc3)nc2s1 +N#Cc1cnn2c(-c3ccc(-n4cnc5ccccc54)cc3)ccnc12 +O=C1NCC(C(=O)NCc2cccc(COCc3ccco3)c2)N1 +COC(=O)C(C)CNc1ccc(Cc2ccncc2)cc1 +COc1cccc(COC(C)C(=O)Nc2ccc3nn[nH]c3c2)c1 +Cc1csc(NC(=O)C2CCN(c3ncnc4[nH]cnc34)CC2)n1 +COCCn1cnc2c(sc3nc(C)cc(C)c32)c1=O +CNC(=O)c1cc(Cl)ccc1NC(=O)C1CC1c1ccccc1F +CC(C)Cc1ccc(C(=O)N2CCN(CCO)CC2)cc1 +CSc1nc2nnc(-c3ccnc(N4CCCCC4)n3)c(C)n2n1 +CNC(=O)Cn1ccnc1-c1ccccc1Br +Cc1cnc(C(=O)Nc2ccc(OCc3ccccc3)cc2)cn1 +CC(=O)NCCNC(=O)NCCOc1ccc(Br)cc1 +COCCN(CC(F)F)C(=O)c1c(C)c2ccccc2oc1=O +COc1cc(C(N)=O)ccc1OCc1ccc(Cl)c(Cl)c1 +O=C(c1[nH]nc2c1CCCC2)N(Cc1ccccc1)C(CO)C1CC1 +CCn1ccnc1-c1nccn1Cc1cc(-c2cccc(OC)c2)no1 +COc1ccccc1OCC(=O)Nc1ccc(-c2nccs2)cc1 +Cc1c(Cl)cccc1Nc1ncnc(NC(C)C)c1N +O=C1NCC(=O)N(CCCOc2ccccc2)c2ccccc21 +CS(=O)(=O)n1nc(-c2ccco2)nc1NCc1ccccc1 +Cc1nonc1NC(=O)c1ccc(OCC(C)C)cc1 +COC(=O)c1ccc(C(F)(F)F)cc1Br +COC(=O)c1ccc(C)c(NC(=O)c2ccc3c(c2)OCCCO3)c1 +COC(=O)c1cc(NC(=O)N(C)CC2CC2)ccc1Br +CC(=O)N1CCCC(Cc2nccnc2-c2ccc(N)nc2)C1 +CC(Cc1cccc(Cl)c1)NC(=O)c1ccc(S(N)(=O)=O)o1 +COc1cccc(C(=O)NCCNC(=O)NCC2CCCO2)c1 +CC(C)c1nnc2n1CCN(C(=O)c1cccc(C(F)(F)F)c1)C2 +CC(C)n1cc(S(=O)(=O)NCc2ccccc2)c2cccnc21 +CCC(=O)N(C)CCc1noc(-c2ccc(C)cc2)n1 +CC(C)(C)OC(=O)C(N)Cc1ccc(C(F)(F)F)cc1 +CNC(=O)c1cnc(COc2ccc(C)cc2)nc1N +COC(CNCc1c(C)n[nH]c1C)c1ccccc1 +CN1C(=O)C(c2nc3ccccc3[nH]2)C(O)c2ccccc21 +COC(=O)c1ccc(C(=O)NC(C)C(C)(C)c2ccccc2)cn1 +Cc1ccc(-c2c(C)sc3ncc(CO)n23)c(C)c1 +CC(=O)Nc1cc(NC(=O)c2ccc(OCC3CC3)cc2)ccc1F +Cc1noc(-c2ccc(C(=O)NC3CCOc4ccccc43)cc2)n1 +CCN(CC1CCOC1)C(=O)CCc1nc(-c2ccccc2)no1 +CCCOc1ccc2c(c1)C(C1CC(=O)C1)NCC2 +COC(C)(C)c1noc(-c2ccc(Cn3ccccc3=O)o2)n1 +Cc1ccc(-n2ncc(C(=O)NC3CCCCC3)c2N)cc1 +COC(=O)CSc1nnc(CC23CC4CC(CC(C4)C2)C3)n1C +COC(=O)CCC(=O)Nc1cccc(-n2cccn2)c1 +C#Cc1cccc(NC(=O)CN(C)C(=O)C(C)C)c1 +COC(=O)C(C)OC(=O)Cc1coc2cc3c(cc12)CCC3 +Cc1csc2ncc(C(=O)NCCC(C)C)c(=O)n12 +COC(=O)CCNC(=O)c1cc(-c2ccccc2)[nH]n1 +CCOC(=O)c1ccc(S(=O)(=O)NCc2cccnc2)cc1 +CCOC(=O)c1c(NC(=O)c2ccccn2)sc2c1CCCC2 +Nc1ccccc1SCc1cc(=O)n2nc(C3CC3)sc2n1 +Fc1ccccc1SCc1nc(-c2ccccn2)no1 +O=C(NCc1ccc(F)cc1)NC1CCN(c2ccc(F)cc2)C1=O +Nc1c(-c2ccco2)[nH]c2cccc(Br)c12 +Cc1ccc(Oc2ccc(NC(=O)c3ccncc3F)cn2)cc1 +Cc1nc(-c2ccccc2)sc1C(C)NS(C)(=O)=O +COCCCNC(=O)c1cccc(C#CCCO)c1 +CSc1ncc(C(=O)NCc2ccccc2)c(C)n1 +CCc1onc(C)c1NC(=O)Nc1cccc(NC(=O)C(C)OC)c1 +NC(=O)c1ccc(OCC(=O)NCc2csc(=O)[nH]2)cc1 +O=C(NCCNc1ncccn1)c1nc(C2CC2)n(-c2ccccc2)n1 +CC1(C)C(=O)OCCN1C(=O)c1cccc(Cl)c1 +Cc1nn(C)c(C)c1C(=O)NCC(O)COCC(C)C +O=C(NC1CCC(O)CC1)c1cn(CCCc2ccccc2)nn1 +CNS(=O)(=O)CCNc1cc(C2CC2)ncn1 +Cc1n[nH]c(Cc2cccc(Br)c2)n1 +COc1ccc(OCC(=O)Nc2cc(F)ccc2OC)cc1 +N#CCn1ccc(NC(=O)CCc2ccccc2F)n1 +Cc1ccc(CN(C(=O)c2sc(C)nc2C)C2CC2)cc1 +CC(C)N1CC(C2NCCc3cc(F)c(O)cc32)CC1=O +CN(CCc1ccc(F)cc1)Cc1ccc(CO)o1 +Nc1nc(-c2cccnc2)ncc1C(=O)Nc1ncccn1 +C=CCn1c(N)c(C(=O)NCCCC)c2nc3ccccc3nc21 +CN(CCc1ccccn1)C(=O)c1c[nH]nc1-c1ccc(Cl)cc1 +CC(C)C(C)NC(=O)CS(=O)(=O)c1ncc(-c2ccccc2)n1C +CCCN(C)C(=O)Cn1cnc2c(cnn2C)c1=O +Cc1ccccc1C(=O)N1CCC(Oc2cccnn2)CC1 +NC(=O)C1Cc2ccccc2N1C(=O)c1ccc2c(c1)OCO2 +C=CCNC(=O)Nc1ccc(NC(=O)Nc2cnccc2C)cc1 +Cc1ccccc1C(=O)N1CCN(c2ccc(O)cc2)CC1 +O=C(c1cccnc1Sc1ccccc1)N1CCCC1 +Cc1csc(=O)n1CC(=O)OCc1csc(-c2ccccn2)n1 +CC1CCN(C(=O)CCCc2ccc3[nH]c(=O)[nH]c3c2)C(C)C1 +Cc1c(-c2n[nH]c3c(N)cccc23)c2ccccc2n1C +CCOc1ncccc1NC(=O)c1cccc2c1OC(C)C(=O)N2 +COc1cc2c(cc1CN1CCc3sccc3C1C)OCCO2 +Cc1cccc(N(CCC(N)=O)Cc2cn3c(C)cc(C)nc3n2)c1 +CCOC(=O)c1c(C2CC2)csc1NC(=O)C(C)n1cccn1 +NC(=O)CC1CCN(C(=O)CCc2ccccc2F)CC1 +CC(=O)c1ccc(NC(=O)NCc2ccnc3ccccc23)cc1C +CC1CC=C(CN(CCC2=CCCCC2)Cc2cc(=O)[nH]c(=O)[nH]2)O1 +COCCN(C)c1ccc2c(ccn2C(=O)OC(C)(C)C)c1 +CC(C)COc1nc(NCc2ccco2)ccc1N +CC(=O)Nc1nc(C(=O)Nc2cc(Cl)c(N)c(Cl)c2)cs1 +CCC(=O)Nc1cc(-c2nc3ncccc3o2)ccc1Cl +Cc1ccccc1CC(=O)NC(C)C(=O)NC(C)(C)C +CC(=O)Nc1ccc(CCNCc2ccc(F)cc2F)cc1 +O=C(Cn1c(=O)oc2ccccc21)NCCc1ccccn1 +CC(Oc1ccc(Cl)cc1)C(=O)NCCCC(N)=O +O=C(NCc1ccco1)Nc1cnn(-c2ccccn2)c1 +CCN1C(=O)c2ccc(Cl)cc2NC1c1cccc(OC)c1OC +CCOCC1CCCN(C(=O)c2cc3cc(C)ccc3o2)C1 +CCn1nnnc1COc1ccc(C(=O)Nc2cccc(C)c2)cc1 +CCN1CCN(C(=O)c2sc3nc4n(c(=O)c3c2C)CCC4)CC1 +Cc1nc2ccsc2c(=O)n1-c1ccc(Cl)cc1 +Cc1noc(C)c1C(C)NC(=O)C(NC(N)=O)C(C)C +Cc1cn2nc(NCCC(=O)N3CC(C)OC(C)C3)sc2n1 +Cc1c(C(=O)NCC2(c3ccccc3)CCC2)oc2c1C(=O)CCC2 +Cc1cc(C)n(-c2ncnc(-n3nnc4ccccc43)c2N)n1 +COCCc1noc(CC2CCc3ccccc32)n1 +O=C(NCc1ccc2c(c1)OCO2)NC1CCN(C(=O)C2CC2)CC1 +COc1cc(C)ccc1CNC(=O)c1scnc1C1CC1 +CC(NC(=O)NCCC1CCCCC1)c1ccc2c(c1)NC(=O)CO2 +CC1CN(CC(=O)NC(C)c2ccccc2)c2cc(N)ccc2O1 +CC1CCCN(C(=O)Nc2ccc(F)c(C#N)c2)C1 +CCOCCCNC(=O)c1cc(=O)oc2cc(OC)ccc12 +CCc1ccsc1C(=O)N1CCN(CC(=O)NCCOC)CC1 +Cc1noc(C)c1CN(C)C(=O)c1ccc(=O)[nH]c1 +CC(=O)Nc1ccc(OCC(=O)NCC(F)(F)F)cc1 +O=C(c1cccc(F)c1)N1CCCC(c2nc3ccccc3s2)C1 +CC(=O)Nc1ccc(CNc2ccc(NC(=O)CC(C)C)cc2)cc1 +COc1cc2c(cc1OC)CN(C(=O)c1cc3ccccc3[nH]1)CC2 +CCC1CCCN(C(=O)CCCOc2ccc3c(c2)CCC(=O)N3)C1 +CCOC(=O)C(C)Sc1ncn(-c2ccccc2)n1 +Nc1ccc(-c2csc(NC(=O)c3ccccc3F)n2)cc1 +COc1ccc(NC(=O)N2CCC(C)CC2)c(Cl)c1 +CN(CC(=O)Nc1nncs1)C(=O)c1ccsc1 +CCCCNC(=O)c1cnc(N2CCC(C)CC2)nc1N +Cc1ccc(C(=O)N2CCN(C(C#N)c3ccc(F)cc3)CC2)cc1 +Cc1ncnc(N2CCCC(CO)(CCCc3ccccc3)C2)c1C +COCC(C)NC(=O)CN(C)S(=O)(=O)c1ccccc1 +COc1ccc(CNC(=O)c2coc(-c3ccccc3)n2)cc1F +Cn1c(=O)n(C)c2cc(-c3cc(Cl)c(C#N)cn3)ccc21 +N#Cc1c(NC(=O)c2ccccc2)sc2c1CCC2 +Cn1ncc2c(=O)n(CC(=O)N(CC3CCOC3)C3CC3)cnc21 +CCCc1nnc2sc(NC(=O)c3ccc(C)cc3)nn12 +COc1ccc(C(=O)Nc2ccccc2CO)cc1Br +CN1CCOC(C(=O)N=c2[nH]ncn2-c2ccccc2)C1 +COc1ccccc1C1c2c(C)n[nH]c2Nc2[nH]c(=O)[nH]c(=O)c21 +CC(C)c1csc2nc(Cc3ccn(C(C)C)n3)[nH]c(=O)c12 +CCCNC(=O)CCc1nc(-c2cccc(Cl)c2)no1 +Cn1cc(CC(=O)Nc2ccc(-c3cc[nH]n3)cc2)c2ccccc21 +Nc1cccc(S(=O)(=O)Nc2ccc(Cl)cc2)c1 +CC(NC(N)=O)C(=O)NCc1nc2ccccc2n1C +CC1CC(=O)Nc2c(Cl)cc(Cl)c(N)c2O1 +O=C(CN1CNc2ccccc2C1=O)NC1=CC2N=CC=C2C=C1 +Cc1nc(CN2CCN(C(=O)c3cc(CC(C)C)no3)CC2)cs1 +Cc1cccc(CN2CCN(C(=O)c3ccc(O)cc3)CC2)c1 +CCCN(CC(=O)OC)C(=O)c1sc(C)nc1C +Cc1nc(SCC(=O)Nc2sc3c(c2C#N)CCCC3)oc1C +COc1ccccc1CN(C)c1cccc(N)c1C +CC(C)n1cc(Br)cc1C(=O)NCC1CCCOC1 +O=C(COc1ccc2c(c1)CCCC2=O)c1ccccc1 +COc1ccccc1CN(C)C(=O)c1ccc(NC(=O)C2CC2)s1 +CCN(CC(=O)NCc1ccc(F)cc1)C(=O)c1ccc(C#N)cc1 +CCOc1ncc(C(=O)Nc2cccc(-n3cnnc3)c2)cc1Cl +Cn1cccc1CNC(=O)c1n[nH]c2c1COc1ccccc1-2 +CCN(Cc1cccc(NC(=O)NC(C)c2ccncc2)c1)C(C)=O +Nc1ccccc1-c1nc2ccccc2n1CCO +CCc1ncnc2c1CCN(C(=O)c1cccc(C)n1)CC2 +CN(Cc1cccc(Cl)c1)C(=O)Cn1c(=O)oc2ccccc21 +O=C(Nc1ccc2c(c1)COC2)c1cc(F)cc(Br)c1 +COc1nn(C)cc1C(=O)N1CCC(Oc2cccnn2)CC1 +O=C(CCC1CCCO1)NCC(=O)Nc1cc(Cl)ccc1Cl +Nc1onc(-c2ccccn2)c1-c1cccc(F)c1 +O=C(Nc1cccc(F)c1)c1cc2n(n1)CCCC2 +N#CCCn1cccc(OCc2ccccc2F)c1=O +Cc1cnn(C2CN(Cc3csc(-c4ccc(C)o4)n3)C2)c1 +CCSc1nnc(N)n1C(C)C(=O)NCc1ccco1 +N#CC1C(=O)Nc2c(cnn2C2CCCC2)C12CCCCC2 +Cc1ccc(OCCn2c(=O)oc3cc(N)ccc32)cc1 +COc1ccc(CCC(=O)N2CC(c3nc(C)no3)C2)cc1 +CCc1nnc2n1CCN(C(=O)c1ccc(-c3ccco3)[nH]c1=O)C2 +CC(C)C(NC(=O)c1ccc2c(c1)OCC(=O)N2)c1ccc(F)cc1 +CSc1cccc(NCC(=O)Nc2ccccc2)c1 +CCC(C)NC(=O)C(NC(=O)c1ccco1)C(C)C +CCOc1ccc(CNC(=O)Nc2ccncc2)cc1OC +Cn1c(=O)c2cc3cc(Cl)c(Cl)cc3nc2n(C)c1=O +Cc1cc(NC(=O)C2CCCCC2)n(-c2ccccc2)n1 +CCN1CC(C(=O)NCC2(c3ccccc3)CC2)CC1=O +CC(C)Nc1cncc(CC2CCCN(S(C)(=O)=O)C2)c1 +COc1cc2c(cc1OC)CN(C(=O)CCn1cc(C)cn1)CC2 +CCOc1cccc(CCC(=O)Nc2cccc(O)c2)c1 +CC(C)C(NC(=O)C1CC(=O)N(C)C1)c1ccccc1 +COCCCNC(=O)COc1ccc(Br)cc1 +CC1=CC2(Nc3cc(C)cc(C)c3O2)C(C(N)=O)=C(N)O1 +COc1cc(C)sc1C(=O)N1CCCC(O)C1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)c1cccc2[nH]ccc12 +COc1ccc(COc2ncnc3ccccc23)cc1F +CN(Cc1cc(F)cc(F)c1)C(CCO)c1ccccc1 +CCC1CCC(NC(=O)c2ccc(C(=O)OC)cn2)CC1 +COc1ccc(-c2nc3ccccc3n2CCCO)cc1 +CC(CO)NC(=O)C1(c2cccc(Cl)c2)CCCCC1 +Cc1cccc(CC(=O)Nc2nnc(-c3cc(C)nn3C)o2)c1 +COc1ccc(N2CCCN=C2NC(=O)c2ccccc2)cc1 +Cn1cc(C2NCCc3cc(C(F)(F)F)cc(F)c32)cn1 +Cn1cccc1CN(C(=O)Nc1ccccc1F)C1CC1 +CCC(CNS(=O)(=O)CC#N)c1ccc(Cl)cc1 +CC1(C)CN(c2ccc(S(N)(=O)=O)cc2S(C)(=O)=O)CCO1 +COC(=O)Nc1cccc(OCC(=O)NC2CCCC2)c1 +N#Cc1cccc(OC2CCN(Cc3cnc4ncccn34)CC2)c1 +COc1ccccc1C(C)(C)C(=O)Nc1ccc(-n2cncn2)nc1 +O=C(NCc1ccco1)c1ccnn1-c1ccc2ccccn12 +O=C(Cc1csc(-c2ccc3c(c2)OCO3)n1)NCc1cc[nH]n1 +Cc1ocnc1CNS(=O)(=O)c1cccc(Br)c1 +CC(C)(CNC(=O)C1(c2cccc(F)c2)CCC1)c1ccncc1 +Cc1nc(COc2cccc(C(=O)N(C)CC(N)=O)c2)cs1 +Cc1cnn(C2CN(c3ncnc4sc(C)c(C)c34)C2)c1 +CCC(NC(=O)C1Cc2ccccc2C(=O)O1)C(C)C +CC(NC(=O)Nc1ccc2c(c1)COC2)C(=O)OC1CCCC1 +COc1cc(NC(=O)C2CC=CCC2)cc(OC)c1OC +CC(C)(C)NC(=O)Cn1cnc2ncccc2c1=O +COc1ccc(-n2ccc(C(=O)N(C(C)C)C3CCC3)n2)cc1 +COC(=O)N(C)CC(=O)NCc1ccccc1N1CCCC1 +CN(C)C(=O)Sc1ccc(NS(=O)(=O)c2ccccc2)cc1 +COC1CCC(C(=O)N2CCC(O)(c3cccnc3)CC2)CC1 +c1cncc(-c2nn3c(-c4ccncc4)nnc3s2)c1 +COCC(C)NC(=O)c1csc(S(N)(=O)=O)c1 +CN(C)C(=O)N1CCN(CCCOCCc2ccccc2)CC1 +Cc1ccc2nc(C)cc(C(=O)NCc3cccnc3)c2c1 +COc1ccc(CC(C)CN(C)C(=O)NC2CCN(C(C)=O)C2)cc1 +CNC(=O)CSc1nnc(-c2ccc(OC)cc2)n1N +CCCCc1cc(NC(=O)c2ccc(NC(=O)C3CC3)cc2)[nH]n1 +COC(=O)c1sccc1S(=O)(=O)Nc1ccc(F)cc1 +CCCCNC(=O)c1ccc(N2CCCC2=O)cc1 +O=C(CCS(=O)(=O)c1ccccc1F)NCc1ccccc1 +Brc1ccc(Cn2ccnc2Cc2nccs2)cc1 +CCc1noc(CN(C)CC(=O)c2c(C)[nH]c3ccccc23)n1 +CCn1ccc(C(=O)Nc2sccc2C(=O)NC)n1 +N#Cc1ccc(SCC(=O)Nc2ccccc2C#N)cc1 +CCC(=O)Nc1cccc(NC(=O)C(NC(N)=O)C(C)CC)c1 +CN(CCC(F)(F)F)C(=O)c1ccc(-n2ccnc2)cc1 +O=C(Nc1ccc(SCCN2CCOCC2)nn1)C1CC1 +Cc1cc2nnn(Cc3cccc(C#N)c3)c2cc1C +O=C1OC(C(=O)NCC2CN3CCCC3CO2)Cc2ccccc21 +Cc1noc(C2CCCN(Cc3cccn3Cc3cccs3)C2)n1 +COc1cccc(C(O)c2nccn2Cc2ccccc2)c1 +COc1ccc(C(=O)NCC2COCc3nc4ccccc4n32)cc1 +Cc1nnc2n1CCN(C(=O)c1ccc(OCC3CC3)nc1)C2 +COc1ccc(-c2nnc(-c3nonc3N)o2)c(O)c1 +CC1CN(C(=O)NCc2ccccn2)CC(c2ccsc2)O1 +COC(=O)N(C)CC(=O)N(C)c1c(F)cccc1F +Cc1nnnn1CCC(=O)N1CCCCC1c1ccc(F)cc1 +Cc1cc2nnc(SCCC(=O)Nc3ccccc3)n2c(C)n1 +CN(CC1CC1)C(=O)NCC(C)(C)N1CCOCC1 +CN(Cc1nc2ccccc2s1)C(=O)CCc1ccco1 +O=C(NC1CCCCC1)NC1CCN(C(=O)CCn2cccn2)CC1 +Cc1ccoc1C(=O)NCCCNC(=O)Nc1cc(C(C)(C)C)on1 +CC(OC(=O)c1ccc(-n2ccnn2)cc1)c1ccc(C#N)cc1 +Cc1nc(-c2c[nH]c(C(=O)NC3(C(N)=O)CCCCC3)c2)cs1 +O=C(CN1CCOCC1)N1CCc2sccc2C1c1ccccc1 +O=C(NCC1CCCO1)C1CCCN(c2nc3ccccc3s2)C1 +CN(CCc1ccccc1)Cc1nc2ccccc2c(=O)[nH]1 +CCCN1c2c(cc(C)c(N)c2C)CS1(=O)=O +Cc1cnn(CC2CN(Cc3nc(C4CC4)no3)CCO2)c1 +O=C1C2CCCN2S(=O)(=O)c2ccccc2N1Cc1cccnc1 +Cc1nn2cccnc2c1C(=O)Nc1cccc(-c2ncc[nH]2)c1 +CCOc1ccccc1CNC(=O)NCc1ccn(C)c1 +CCCc1n[nH]c(SCc2nc3ccccc3s2)n1 +Cc1cc(-c2ccccc2Br)nc(N)n1 +c1cn2c(CN3CCOC4(CCCC4)C3)cnc2cn1 +Clc1ccc2nc(-c3nccn3CCCn3ccnc3)ccc2c1 +COc1ccc(Cl)cc1NC(=O)c1cccn1C +CC(C)CC(C(=O)Nc1ccc2sncc2c1)N1CCCCC1=O +Cc1cc(C)c(NC(=O)c2ccccc2N(C)S(C)(=O)=O)c(C)c1 +COc1ccccc1OCCN1CCN(Cc2nc(C)no2)CC1 +Cc1cc(C)c2nnc(SCC(=O)Nc3ccccc3Cl)n2n1 +N#Cc1ccccc1NC(=O)CCC(C#N)c1ccncc1 +O=C(CCn1ncc(=O)c2ccccc21)OCC1CCCCC1 +COc1cc(Br)cc(-c2ccno2)c1O +Cc1ccc(F)cc1CC(=O)N1CCC(O)(C2CCOCC2)C(C)C1 +Cc1nsc(N2CCN(CC=Cc3ccc(C#N)cc3)CC2)n1 +COc1cc(C(=O)NC2c3ccccc3CC2O)ccc1C +COCC(=O)N1Cc2cnn(CC3CCOCC3)c2C(COC)C1 +NC(=O)c1ccccc1OCc1cccc(F)c1F +CNC(=O)CCC(O)c1ccc(OC)c(C(C)(C)C)c1 +CCC(C)NC(=O)Cn1c2ccccc2c2cnn(C)c(=O)c21 +O=C(Cn1c(-c2ccccc2Cl)csc1=O)NC1CCCC1 +CC(C)Cn1ncc(C(=O)NC(C)C(C)(C)C)c1C(F)F +COCC(C)C(=O)N1CC=C(c2ccccc2Cl)CC1 +Cc1noc(CCc2nc(Cc3ccc(Cl)cc3)no2)n1 +Cn1nnnc1SCC(=O)Nc1cc(N)ccc1Cl +COc1cccc(C(C)CC(=O)NCc2n[nH]c(=O)[nH]2)c1 +COCC(C)CNC(=O)c1cc(S(N)(=O)=O)ccc1C +O=C(C1CC1)N1CCN(c2ncnc3[nH]cnc23)CC1 +Nc1ccc(-c2nncn2-c2ccccc2)c(O)c1 +Cc1cn2c(CNc3ccccc3F)c(C)nc2s1 +O=C(NCc1n[nH]c(=O)[nH]1)c1cn(-c2cccc(Cl)c2F)nn1 +COc1cc(C2(C(=O)Nc3cccn(C)c3=O)CC2)ccc1C +COc1ccccc1Cc1nnc(SC)n(N)c1=O +Cc1cccc(-c2nc(-c3ccc(O)cc3)no2)n1 +Cc1ccc(CN2CCOC3C(OCc4cccnc4)CCC32)o1 +COc1ccc(NC(=O)CN(C)C(=O)c2cnc(C)cn2)cc1 +Cc1nc(C)c(C(=O)Nc2ccnc(Oc3ccccc3Cl)c2)o1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)c1ccc2cc[nH]c2c1 +CN(CCOCC1CC1)C(=O)c1cccc(S(C)(=O)=O)c1 +CCN(CC)C(=O)c1cc(C2CC2)nc2c1nc1n2CCCCC1 +Cc1occc1C(=O)NCC(=O)Nc1ccc(OC(F)F)c(F)c1 +CCC(CC)C(=O)N1CC(c2nc(-c3ccccc3)no2)C1 +Cc1occc1C(=O)NCc1ccccc1NS(C)(=O)=O +O=C(CN1CCOCC1)N1CCCC1c1cccs1 +O=C(c1cc(COc2cccc(F)c2)[nH]n1)N1CC=CC1 +Cc1ccc(C(=O)CNC(=O)c2ccccc2F)cc1C +CN1C(=O)Cc2cc(C(=O)NCc3ccc(F)c(Cl)c3)ccc21 +O=C(Nc1onc2c1CCCC2)c1cc(OCc2ccccc2)no1 +CCCNS(=O)(=O)c1ccc2c(c1)N(C(=O)CC)CC(C)O2 +CC(=O)Nc1nc(C(=O)NC(C)c2nnc3ccccn23)cs1 +COC(=O)c1ccc(CSc2ccc(NC(=O)C(C)C)nn2)o1 +Cc1ccc(S(=O)(=O)Nc2ccc(C(=O)NC3CC3)cc2)cc1 +Cc1nnc(SC(C)C(=O)Nc2nc(C)c(C)s2)s1 +CCn1ncc(C(=O)NCc2cnn(-c3ccccc3OC)c2)c1C +CCC(=O)N1CCN(c2ccc3c(c2)CCC3)C(=O)C1C +Nc1c(C(=O)NCc2cccs2)nnn1-c1ccccc1Cl +COC(=O)CC(C)NC(=O)Nc1cccc(Cl)c1C +COc1cc(N)c(CCC(=O)N(C)c2ccccc2)cc1OC +CCCNC(=O)c1cnn(-c2cc(-c3nc(C)no3)ccn2)c1C +Cc1cc(C)cc(NS(=O)(=O)c2ccc3c(c2)sc(=O)n3C)c1 +Cc1ccc(Br)cc1NCC(=O)N1CCOCC1 +Cc1nnc(-c2coc(S(=O)(=O)N3CCCCCC3)c2)o1 +CCOc1cccc(C(=O)CCc2nc(C)c(C)s2)c1 +O=C(Nc1nnc(CCSc2ccccc2)o1)c1ccccc1 +CC(=O)NC(C)c1ccc(-n2cc(C(N)=O)nn2)cc1 +CC(Oc1ccc(Br)cc1)C(=O)Nc1ccncc1 +CC(C)(C)OC(=O)N1CCC(NC(=O)NC2CCCCC2)CC1 +O=c1oc(-c2ccc(F)cc2)nn1Cc1cccnc1 +Cc1nc(CCNc2nc3nonc3nc2N2CCCC2)sc1C +COc1ccc(C(=O)OCc2nc(N)nc(N)n2)c(OC)c1 +CN(CC(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1)c1ccccc1 +Cc1ncsc1C(=O)NCc1ccnc(SC(C)(C)C)c1 +CC1(C)OC(=O)C(C2NCCc3ccccc32)C(=O)O1 +COc1ccc(S(=O)(=O)NCCC(=O)Nc2cccnc2)cc1 +Cc1ccc(C(=O)NCCC(=O)NCc2ccccn2)n1C +CNC(=O)c1ccc(NC(=O)c2cc(Cl)ccc2Cl)cc1 +FC(F)c1nnc2ccc(N3CC4CCC3C4)nn12 +COCc1cc(-c2nc(-c3ccc(F)cc3Cl)no2)no1 +CC(C)CC(=O)N1CCC(NC(=O)C2Cc3ccccc3O2)CC1 +CCCC1CN(C(=O)c2cccc(N(C)C)c2)CCO1 +O=C(NC1CCCc2ccccc21)N1CCN(Cc2ccon2)CC1 +Cc1cc(CN2CCN(C(=O)Nc3cccc(F)c3F)CC2)no1 +O=C(NCc1ccc(CN2CCCC2=O)cc1)C1CCOCC1 +Cc1nnc(COC(=O)CNC(=O)Cc2ccccc2)o1 +CC(NC(=O)c1ccc(N2CCCC2=O)cc1)c1ccncc1 +CCN1CCN(S(=O)(=O)c2ccc3c(c2)CCCN3)CC1 +Cn1c(=O)c2ccn(CC(=O)Nc3ccccc3)c2n(C)c1=O +O=C(NCc1cc(-c2ccccc2)no1)c1ccnc(NC2CC2)c1 +CC(C)CCC(C)NC(=O)c1cc2ccccc2oc1=O +Cc1noc(COCC(=O)Nc2cccc(C(F)(F)F)n2)n1 +CC(C)c1n[nH]c(NC(=O)c2occc2Br)n1 +CC(NC(=O)NCc1ncn(C)n1)c1ccc(F)cc1Cl +CC(C)(O)C1CCCN1C(=O)Nc1ccc(F)cc1OCC1CC1 +COc1ccc(CCCNC(=O)c2ccc(C)[nH]c2=O)cc1 +CC(=O)Nc1cccc(NC(=O)NC(c2ccccc2)c2ccco2)c1 +COc1cc(C)sc1C(=O)Nc1nnc(-c2ccccn2)s1 +COC(=O)CCC(=O)Nc1ncc(-c2ccccc2)s1 +O=C(c1ccc(-c2cnn(-c3ccccc3)c2)nc1)N1CCCC1 +Cc1cc(NC(=O)c2cnccn2)ccc1S(N)(=O)=O +CC(C)(C)OC(=O)N1CCCC(O)(C(F)(F)F)C1 +CCC(Oc1ccccc1)C(=O)Nc1cc(N)ccc1F +O=C(CCNC(=O)c1cccs1)NC1CCCCC1 +CN(CC1OCCc2ccccc21)C(=O)c1cccc(-n2ccnn2)c1 +CN(c1ccc2ccccc2c1)S(=O)(=O)c1cccc(C(N)=O)c1 +Cc1nc(C2CCCN2C(=O)c2cscn2)no1 +Cc1ccc(-c2n[nH]c(=NC(=O)Cc3ccccc3C)[nH]2)s1 +COc1ncnc(N)c1CN(C)C(C)Cc1ccsc1 +CC(Cc1cccs1)NC(=O)CCC(=O)N1CCOCC1 +CCn1ccc(-c2cc(C(=O)OC)c3c(-c4ccccc4)noc3n2)n1 +O=C(NCCCO)Nc1cccc(CN2CCCCC2=O)c1 +CCCS(=O)(=O)NCc1c(CC)noc1CC +Cc1ccc(CNc2ncnc(NCCN3CCOCC3)c2N)cc1 +CCc1nc(CNC(=O)Nc2cc(-c3ncco3)ccc2C)cs1 +COc1cc(CNC(=O)c2cccc(C)c2O)ccn1 +O=C(Cc1cccc(C(F)(F)F)c1)Nc1cccc(O)c1 +O=C(Nc1ccccc1)C1CCCN1C(=O)NC(C1CC1)C1CC1 +NC(=O)CSc1nccn1-c1cccc(Br)c1 +O=C(NCc1cccnc1)Nc1ccc2c(c1)CCO2 +CN1C(=O)Cc2cc(-c3cc(=O)[nH]c(N)n3)ccc21 +O=C(c1cc(-c2ccco2)n[nH]1)N(CC(F)(F)F)C1CCOCC1 +CC(C)c1nnc2sc(-c3ccc(F)c(F)c3)nn12 +C#CCN(Cc1ccc(F)cc1)Cc1n[nH]c(=O)[nH]1 +CCC(C)(C)NC(=O)CSc1nnnn1-c1cc(C)ccc1OC +CC(Cn1nnc2ccccc21)NC(=O)Cc1c[nH]c2ccccc12 +CNC(=O)NCC(=O)NC(Cc1ccccc1)C1CCCC1 +COc1ccc(OC)c(NC(=O)C2CC=CCC2C(=O)OC(C)C)c1 +OC(CN(Cc1cccc(-n2cccn2)c1)C1CC1)c1ccccc1 +COC(=O)Cc1ccc(NC(=O)C2CCCO2)cc1 +Cc1nnc(COc2ccc3c(C)cc(=O)oc3c2)o1 +Cc1cnc(C(=O)N2CCn3nnc(COCC4CC4)c3C2)cn1 +Cc1cccc(=NS(=O)(=O)c2ccc3c(c2)C(C)(C)C(=O)N3C)[nH]1 +Cc1cc(CC(=O)NC2CCOC2c2ccc(Cl)c(F)c2)n[nH]1 +Cc1nc2ccccc2c(C)c1CC(=O)NC(C)Cn1cncn1 +CC(C)c1noc(CN2CCN(C(=O)c3cc[nH]n3)CC2)n1 +CC(=O)c1c(C)[nH]c(C(=O)Cn2ccc(-c3ccsc3)n2)c1C +CN(Cc1ncnn1C)C(=O)Nc1ccc(OC(F)F)cc1 +Cc1oncc1-c1ncc2c(Br)ccn2n1 +Cc1cccc(N2CCN(C(=O)c3ccc(-n4cncn4)nc3)CC2)c1 +COc1ccc(N2CC(C(=O)N3CC(C)CC(C)C3)CC2=O)cc1 +CCOC(=O)CN(CC)C(=O)C1Cc2cc(Cl)ccc2O1 +Cc1cccc(OCCNC(=O)Cn2cnc(C3CCC3)cc2=O)c1 +COC(=O)c1cc(-c2cccnc2)nc2c1c(C)nn2C +COc1cccc(C(=O)Nc2ccc(OCCO)cc2)c1F +NC(=O)Cc1csc(SCc2ccccc2F)n1 +O=C(Nc1nc(C(=O)NCc2cccnc2)co1)c1ccsc1 +COCCOC(=O)c1c(C)oc2cc(Br)c(OC)cc12 +CN(Cc1ccccc1)C(=O)C1=C2c3ccccc3C(=O)N2CC1 +O=C(NCc1ccc(Cl)cc1Cl)c1[nH]nc2c1COCC2 +CC(=O)Nc1ccc(C(F)(F)F)cc1NCc1nnc(C2CC2)o1 +COc1ccccc1NS(=O)(=O)c1ccc(NC(=O)C2CC2)cc1 +COC(=O)c1cccc(NCc2nc(C)c(C(C)=O)s2)c1 +COCCOc1ccc(NC(=O)C2OCCc3ccccc32)cn1 +O=C(OCc1cn2ccccc2n1)C1CCCN1c1nccs1 +CCCN1Cc2cccc(C(=O)Nc3ccccc3OC)c2C1=O +COCCCCNC(=O)c1ccnc(-n2cncn2)c1 +Cc1ccc(C)c(C(O)CCCC(=O)NCc2ccccn2)c1 +CCn1c(=O)oc2ccc(C(=O)NCc3cccc(C)c3)cc21 +Cc1cc(CCc2ccc(Cl)cc2)c(C#N)c(=O)[nH]1 +CCS(=O)(=O)c1ccc(COC(=O)C2CCCN2)cc1 +OCCNc1c2c(nc3nc4ccccc4n13)CCC2 +CC(=O)N1CCc2cc(NC(=O)N(C)Cc3c(C)noc3C)ccc21 +COc1cccc(NCC(O)c2ccc(OC)c(F)c2)c1 +O=C(CCc1ccccn1)Nc1ccc(F)cc1F +CC(C)C(=O)Nc1cccc(NCc2csc(C(C)C)n2)c1 +FC(F)(F)c1cccc(NCc2cncnc2)c1 +COCc1cccc(C(=O)NC(c2ccccc2)c2nccn2C)c1 +COCC(=O)N(Cc1ccccn1)c1ccc(F)cc1 +Cc1cc(NCCCOc2ccc(C#N)cc2)ccc1C(=O)N(C)C +CC(C)N(C)S(=O)(=O)N(C)Cc1cnn(C)c1 +CC(NC(=O)N1CCC(C(N)=O)C1)c1ccc2c(c1)CCC2 +COc1c2ccc(C(=O)NCCn3nc(C)cc3C)cc2nn1C +O=C1CCN(C(=O)CCCOc2ccccc2)CC1 +N#CCC(Nc1cccc(F)c1F)c1ccccc1 +O=C(c1cccc(OCc2cccnc2)c1)N(Cc1ccco1)C1CC1 +Cn1nc(CNC(=O)Cc2ccccc2Cl)cc1-c1ccncc1 +Cc1[nH]c2ccccc2c1C(=O)CSc1nccn1C +COc1ccc(C#CCNC(=O)c2cnn(-c3ccccc3)n2)cc1 +Cc1c(C(=O)NC(C)(C)C)nnn1-c1ccccc1 +CCNC(=O)c1cccc(-c2cccc(-c3cc[nH]n3)c2)c1 +O=C(Cc1ccsc1)N1CCN(c2ccc(Cl)cn2)CC1 +Cc1cc2[nH]c(=O)cc(C)c2c(C)c1S(=O)(=O)N1CCCCC1 +C=CCNc1nnc(SCC(=O)c2ccc(C)cc2)s1 +Cc1cccc(CNC(=O)Nc2ccc(F)cc2)c1 +O=C(NCCc1ccsc1)c1ccc(Cl)cc1 +COc1ccc(S(=O)(=O)NCC(C)(O)C2CC2)cc1 +O=C(Nc1nnc(Cc2ccccc2F)s1)C1CC=CC1 +Cc1ncsc1CNC(=O)c1ccc(OCC(F)F)nc1 +NC(=O)c1c[nH]c(C(=O)Nc2c[nH]cc(Br)c2=O)c1 +CC1CCCC(C)N1C(=O)CCc1nc(-c2ccsc2)no1 +Cc1ccc(NC(=O)Cn2ccnc2S(C)(=O)=O)c(Cl)c1 +CCC(=O)c1ccc(Cl)c(S(=O)(=O)NC2CC2)c1 +CCOc1cc(F)ccc1NC(=O)CNC(C)=O +O=c1c2[nH]cnc2n(-c2ccccc2)c(=O)n1Cc1ccccc1 +CC(c1ccccc1)N(C)C(=O)COc1ccccn1 +CCN1C(=O)C(OC(=O)c2cscn2)CC1c1ccc(OC)cc1 +CCOc1ccc(NC(=O)Cn2c(=O)n(C)c3ccccc32)c(C)c1 +O=C(Nc1cc(F)c(F)c(F)c1)c1ccsc1 +N#CCS(=O)(=O)N1CCC(c2ccccc2)C1 +C=CCc1ccccc1OCC(O)CN1CCn2c(C)nnc2C1 +COc1ccc(OCCC(=O)NC2CCC(C)CC2)cc1 +Cc1noc(C)c1C(C)NC(=O)C1C2CC3CC(C2)CC1C3 +COc1cccc(CN(C)C(=O)CNc2ccc(C(C)=O)cc2)c1 +O=C(NCCC(=O)N1CCN(c2ccccc2)CC1)c1ccccc1 +C#Cc1cccc(N(Cc2ccccc2)C(=O)Cn2cnnn2)c1 +CCc1nsc(N2CCN(C(=O)c3c(C)cc(C)cc3C)CC2)n1 +Cn1cc(CCNC(=O)NC2CCCc3ccccc32)cn1 +CCC(C)NC(=O)CN1CCc2cc(-c3csc(C)n3)ccc21 +CCC(C)NC1=NS(=O)(=O)c2c(Cl)cc(Cl)cc2N1 +CC1(C)CCC(CNC(=O)c2cc3c([nH]c2=O)CCCC3=O)CC1 +COc1cc2[nH]c(=O)n(CCC(C)C)c(=O)c2cc1OC +Nc1nc(-c2ccc(F)cc2)ncc1C(=O)N1CCCCC1 +CCOc1ccc(C(=O)NCc2ccc(F)cc2F)nn1 +O=C(NCc1cn2cc(Br)ccc2n1)c1cnn[nH]1 +CC1CN(C(=O)c2ccc(-n3ccnn3)cc2)CC(C(N)=O)O1 +O=C(NCc1cccs1)c1sc2ncccc2c1-n1cccc1 +CC(C)CN1CCOC(COC(=O)c2coc(-c3ccccc3)n2)C1 +COc1ccc(C(N)=O)cc1NCCn1nc2ccccn2c1=O +CC1(NC(=O)c2cccc(OCC(F)F)n2)CCOCC1 +CS(=O)(=O)N1CCN(C(=O)c2csnn2)CC1 +CC(C)NC(=O)C1CCCN(c2ccnc(-c3ccc(F)cc3)n2)C1 +CN1CC(NC(=O)N(CCCO)C2CCc3ccccc32)CCC1=O +COc1ccc(C(=O)NCC(OC)c2cccc(F)c2)cc1OC +Cc1ccc(C(=O)CCC(=O)NCC(=O)NC2CC2)s1 +CCc1noc(CC)c1CC(=O)Nc1ccc(-c2ncc[nH]2)cc1 +CCCn1c(=O)c2sccc2n2c(=O)n(Cc3ccccc3)nc12 +CC(=O)Nc1ccc(C(=O)Nc2ccc(NS(C)(=O)=O)cc2)cc1 +CCc1cc(C(=O)N2CCCC2c2ccco2)cc(=O)[nH]1 +CCC(C#N)S(=O)(=O)c1ccc(F)c(Cl)c1 +Cc1cc2[nH]c(=O)[nH]c2cc1S(=O)(=O)N1CCCCCC1 +O=C1NCCN1C1CCN(c2ccc(C(F)(F)F)cn2)CC1 +CCc1ccc(NC(=O)Cc2cccc(N)c2)cc1 +Cc1cc(O)ccc1NC(=O)Cc1c[nH]c2ncccc12 +O=C(C1CCOC1)N1CCCn2cnc(COCc3ccco3)c2C1 +Cn1c(-c2ccccc2)c(C(=O)CN2CCOCC2)c2ccccc21 +C#CCn1nc(CC)n2c(cc3oc(C)cc32)c1=O +C=C1CC(O)C2C(C)C(=O)OC2C2C(C)C(=O)CC12 +CNc1ccc(S(=O)(=O)NCCc2ccccc2)cn1 +Cc1cccc(NS(=O)(=O)c2ccccc2Br)n1 +C=CCN(Cc1cc(OC)c2c(c1)OCO2)CC(F)(F)F +N#Cc1cccnc1N1CCCN(C(=O)CC(C2CC2)C2CC2)CC1 +CCc1nonc1NC(=O)COc1ccc(C)cc1 +CCOC(=O)C(Cc1c(-c2ccccc2)cnn1C)NC +c1cncc(-c2ncc(CN3CCC(OC4CCCC4)CC3)s2)c1 +CCOC(=O)c1ccc(CNC(=O)NCc2ncn(C)n2)o1 +CC(Oc1ccccc1C(N)=O)C(=O)NCC(F)(F)F +O=C(c1ccc(-c2ccccc2F)o1)N1CCCC1Cn1cccn1 +CC(=O)Nc1ccc2nc(NC(=O)COc3ccc(C)cc3)oc2c1 +COc1ccc(C(=O)CNC(=O)C2(n3cnnn3)CCCCC2)cc1 +COCCNC(=O)c1nccc2c(N)cc(Br)cc12 +Cc1nc(SCC(O)CO)c2c(C)csc2n1 +OC1C=C(C2NCCc3ccc(F)c(F)c32)CC(O)C1O +N#Cc1ccc(Br)cc1OCc1ccoc1 +Cc1noc(C)c1CCc1nc(C2CCOCC2)n[nH]1 +O=C(C#Cc1ccccc1)Nc1ccc2c(c1)CCC2 +C=CCN(CCc1ccccc1)Cc1nc2c(cnn2C)c(=O)[nH]1 +O=S(=O)(c1cccc(Cl)c1)N1CCN(CC(O)C2CC2)CC1 +Cc1noc(C2CCOC3CCN(C(=O)c4sccc4C)CC32)n1 +COc1ccc(NC(=O)NC(c2cc(C)ccn2)C2CC2)c(OC)n1 +Cc1cccc(Nc2nnc(SCC(=O)N(C)C)s2)c1 +CCc1nnc(NC(=O)CCn2ncc3ccc(Cl)cc32)s1 +CCCCCNC(=O)N1CCCC(C(=O)Nc2nncs2)C1 +CCS(=O)(=O)N(C)c1ccc(C(=O)NCc2ccc(C)cc2)cc1 +COCCN(CCOC)C(=O)C1COc2ccc(F)cc2C1 +CN(CCOc1ccc(F)cc1)C(=O)c1ccc2c(c1)NC(=O)CO2 +COc1ccc(-c2nnnn2-c2ccc(C)c(C)c2)cc1N +Nc1ccccc1C12NCCCN1C(=O)c1ccccc12 +CC1CCCCC1N(C)C(=O)CSc1nc(-c2cccnc2)n[nH]1 +CN(CC(=O)N1CCNCC1)C(=O)Nc1ccc(Cl)cc1 +Cc1cc(C2CCCN2S(=O)(=O)c2cccs2)on1 +COC(=O)c1cnc(COC(C)=O)c(C)c1OC +COC(=O)c1c(-c2ccc3c(c2)CCCO3)noc1N +CC(=O)c1ccccc1Oc1ccc2c(c1)CCC(=O)N2 +Cc1ccccc1-n1cnnc1SCC(=O)NCc1ccco1 +N#Cc1ccccc1Cn1c(=O)nc2n1C(=O)N(c1ccc(F)cc1)C2 +COC(=O)CCN(C(=O)C1CCC1)c1ccccc1C +Cc1cccc(C)c1NC(=O)c1cc(CN2CCOCC2)on1 +N#Cc1ncccc1OCc1nc(COc2ccccc2)no1 +O=C(CCCN1CCCC1=O)NCc1cccc(C(F)(F)F)c1F +CCc1nn(CCc2ccccn2)c(=O)c2ccccc12 +O=C(NC1CC1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +COCCn1c(C(C)=O)nc2cccc(Cl)c21 +Cc1csc(CNc2ncnc3sccc23)n1 +O=S1(=O)N=CN(Cc2cccc(C(F)(F)F)c2)c2ccccc21 +CC(NC(=O)CN(C)CCC#N)c1ccc(Br)cc1 +CC(C(=O)c1ccccc1)n1nc(-c2cccs2)ccc1=O +O=C(Nc1ccc(CCc2nc3ccccc3[nH]2)cc1)c1ccncc1 +CN(CCn1c(=O)[nH]c2ccccc2c1=O)c1ccccc1 +O=C(c1c(F)c(F)cc(F)c1F)N1CCOCC1 +Cn1c(CN2CCOC(Cn3cccn3)C2)cc(=O)n(C)c1=O +C=CCCC(CN1CCN(C(C)=O)CC1)Oc1ccc(C#N)cn1 +Nc1ccc2nc(C(F)(F)F)n(Cc3ccc(O)cc3)c(=O)c2c1 +CC(C(=O)N1CCCC1)N1CCOC(c2ccc(F)c(Cl)c2)C1 +Cc1cc(C)nc(NC(=O)CSc2nc3ccccc3[nH]2)n1 +CCn1c(CN(C)c2ncc(C(N)=O)cc2Cl)nc2ccccc21 +CCN(CC)S(=O)(=O)c1ccc(=O)n(CC(N)=O)c1 +Cc1noc(C)c1N(C)C(=O)c1cccc2ncccc12 +COc1ncccc1CNC(=O)N1CCN(C(C)=O)CC1 +CC(C)C(=O)Nc1nc(CC(=O)N(CC2CC2C)C(C)C)cs1 +O=C(CSc1nnc2n1CCCCC2)NC(C1CC1)C1CC1 +CC(C)c1nc(NC(=O)CCCc2cn(C)c3ccccc23)n[nH]1 +COc1cc(C(=O)OC2CCCC2OC)ccc1C +CN(Cc1cccs1)C(=O)CNc1cccc(F)c1 +CCOC(=O)CNC(=O)COc1cc(C)cc(C)c1 +O=C(c1cc(COc2ccc(-n3cncn3)cc2)on1)N1CCCC1 +CCn1cc(S(=O)(=O)N2CCOCC2CC(C)C)cn1 +O=C(CNC(=O)c1ccccc1)Nc1ccc(OC(F)(F)F)cc1 +C=CCOc1ccc(CNc2c(C)nn(CC)c2C)cc1 +CC(=O)Nc1ccc(-c2csc(NC(=O)c3cc[nH]n3)n2)c(F)c1 +CCOCC(=O)N(C)Cc1nc2ccsc2c(=O)[nH]1 +Cc1cnc(-c2cccc(NC(=O)NC3CCCC3C)c2)o1 +COc1nn(C)cc1C(=O)NCC#CCOc1ccccc1C(N)=O +CCNC(=O)CNC(=O)NCC1CN2CCCCC2CO1 +CCc1nn2c(=O)cc(CNc3ccc(Cl)cc3C)nc2s1 +Cc1cc(C(=O)Nc2ccccc2NC(=O)OC(C)(C)C)n(C)n1 +COC(=O)c1cc(F)c(C)c(NCC(=O)NC(C)(C#N)C2CC2)c1 +CC(C)c1nnc2n1CCN(C(=O)c1cc(-c3ccccc3)n[nH]1)C2 +CCOc1ccc(OCC)c(NCc2cnn(C)c2)c1 +Cc1cccc(NC(=O)c2cccn2-c2cccnc2C)c1C +CCCN(Cc1ccsc1)S(=O)(=O)c1ccc(F)c(F)c1 +CC(=O)Nc1ccc(CNc2ccc(N3CCCC3=O)cc2)cc1 +Cc1ccc(C)c(OCC(=O)OCC(=O)c2cc(C)n(C)c2C)c1 +COCCN1CCN(C(=O)c2ccc(N3CCOCC3)nc2)CC1 +CC(=O)c1ccc2c(c1)N(C(C)C(=O)OCC(C)C)C(=O)C(C)O2 +Cc1noc(C)c1CCCNC(=O)Nc1ccc2[nH]ccc2c1 +CCC(C)NC(=O)NCc1ccc(N(C)C(=O)c2ccncc2)cc1 +Cc1cccc(CNC(=O)Cn2cc(C)c3ccccc32)n1 +COC(=O)C(C)(NC(=O)c1ccc(OC)c(OC)c1)c1ccccc1 +Cc1nc(CSc2cc(C#N)ccn2)nc2ccccc12 +COc1ccc(Cc2ncc3c(n2)CN(C(=O)C(C)(C)OC)C3)cc1 +CC(C(=O)Nc1ccc(C#N)cn1)c1cccs1 +O=c1[nH]c2ccccc2c(=O)n1-c1cccc(Cl)c1 +Cn1ccc(CN2CCN(C(=O)c3ccc(F)cc3F)CC2)c1 +Cc1nnc(SCC(=O)N2CC(C)CC(C)C2)s1 +Cc1nn(C)c(C)c1NC(=O)c1cccc(OCc2ccccc2)c1 +Oc1ccccc1CC1NCCc2ccc3c(c21)OCO3 +O=S(=O)(NCc1nc(-c2ccccc2)no1)c1ccc(Cl)cc1 +N#Cc1ccc(OC2CN(C(=O)CCc3ccncc3)C2)cc1 +COc1ccc(CNC(=O)c2oc3c(F)cccc3c2C)cc1OC +Cc1cccc(OC(=O)C2CCN(C(=O)C3CC3)CC2)c1 +COc1ccc(-c2cc(NC(=O)c3cnccn3)c(=O)oc2C)cc1 +CC1CN(C(C)(C)CNC(=O)NC(CO)c2ccccc2)CC(C)O1 +CC(=O)c1c[nH]c(C(=O)N2CCN(C(=O)c3ccccc3F)CC2)c1 +O=C(Cn1cnnn1)N(Cc1ccc(Cl)cc1)C1CC1 +Cn1c(=O)c2ncn(CC(=O)NC3CC3)c2n(C)c1=O +CN(C)C(=O)Cn1cc(C(=O)NCCc2cccc(Cl)c2)nn1 +CC(Oc1ccc(C#N)cc1)C(=O)Nc1ccccc1-n1ccnc1 +O=C(Nc1ccncc1)c1c(F)ccc(F)c1F +CC(=O)c1ccc(NC(=O)Cn2cnc3oc(C)c(C)c3c2=O)cc1 +O=C(COC(=O)c1ccc(O)cc1)Nc1ccccc1F +Nc1cccc(N2CCN(C(=O)c3cccc(Cl)c3)CC2)c1 +CCOc1cc2c(cc1NCc1nnc(C3CC3)o1)OC(C)C2 +Cc1ccc(CN(C)C(=O)Nc2ccc(N3CCCC3=O)cc2)s1 +Cn1ncc2c(N3CCN(C(=O)CN4CCOCC4)CC3)ncnc21 +O=C(COc1cccnc1)NCCCn1cccc1 +Fc1ccc(Cc2ncc(-c3nc(-c4ccncc4)no3)s2)cc1 +COc1cc(C(C)=O)ccc1OCc1cccc(C#N)c1 +O=C(NCCCc1nc2ccccc2[nH]1)Nc1ccc(F)cc1F +Cc1n[nH]c(C(=O)Nc2cccc(OC(F)F)c2)c1Br +Cc1ccc(NC(=O)CNc2ccccc2C(=O)N(C)C)c(C)c1 +CCOc1ccccc1CN(C)S(=O)(=O)N1CC(C)CC(C)C1 +CC(Sc1ccc(F)c(F)c1)C(=O)NC1CC1 +C#CCNS(=O)(=O)c1cccc(C(=O)Nc2ccnn2CCC)c1 +CCCCCC(=O)NCc1ccc(-n2cncn2)nc1 +Cc1cc2c(cc1C(=O)N1CC(C)C(O)(C3CCC3)C1)OCCO2 +Cc1c(C(=O)NC(C)C(=O)N2CCCCC2)cnn1-c1ccncc1 +O=C(CCn1cccn1)NCc1ccc(Br)cc1 +CC(=O)N1CCC(C(=O)N(C)c2cccc(C)c2C)CC1 +CCCC1CN(C(=O)C(C)(C)CC2CCOCC2)CCO1 +COc1cc(CC(C)(C)CO)cc(OC)c1OC +O=C(Nc1nnc(C2CCC2)s1)c1ccccn1 +COC(=O)C(C)NC(=O)c1occc1COc1ccccc1 +CCn1nc(C)cc1NC(=O)c1cccc(Cl)c1 +Cn1cc(C(=O)OC(C(N)=O)c2ccc(F)cc2)c2ccccc21 +Cc1csc(CNS(=O)(=O)c2cnn(Cc3ccccc3)c2)n1 +Nc1nc(=O)c2sc(=O)n(C3OC(CO)C(O)C3O)c2[nH]1 +Cn1cc(-c2cc(-c3cc(F)c(F)cc3F)nc(N)c2C#N)cn1 +Cc1ccc(C(=O)CCC(=O)Nc2cccc(C#N)c2)cc1N +Cc1ccc(F)cc1C(=O)N(CCN1CCOCC1)c1ccccc1 +Cc1[nH]c2ncnn2c(=O)c1CCC(=O)Nc1ccccn1 +CCCCN(C)C(=O)CC1Sc2ncccc2N(CCC)C1=O +COc1cccc(C(=O)N2CCC3(CC2)OCCO3)c1 +COCCNC(=O)CNc1ccc(Cl)c(Cl)c1 +COCC(C)N1CCN(C(=O)CCc2ccccc2C)CC1 +CC(=O)c1cccc(NC(=O)CN2C(=O)CNc3ccccc32)c1 +Nc1c(Nc2nc3ccccc3s2)nc[nH]c1=O +COC(=O)c1ccc(NC(=O)CN2CCc3ccccc32)cc1 +O=C(NCc1ccc(N2CCCC2=O)cc1)c1c(F)cccc1Cl +CCCC(=O)C1C(=N)CC(C)(C)C(C(=O)OC)C1=O +CC(C)(C)OC(=O)N1CCC(C(=O)NCC(F)(F)F)C1 +Brc1ccc2c(c1)OCC1(CC1)CO2 +CC(C)CCCNC(=O)Nc1ccc(C(N)=O)cc1 +CCOC(=O)C(CC)Sc1nnnn1C1CCCCC1 +CCCc1nc2oc3c(NCCO)ncnc3c2c2c1CCCC2 +CN(CC(N)=O)C(=O)COc1ccc(Cl)cc1Cl +CN(Cc1ccccn1)C(=O)c1nc(C2CC2)n(-c2ccccc2)n1 +O=C(NCc1cc(C2CC2)n(C2CCCC2)n1)c1ccco1 +COc1ncccc1N(C)C(=O)c1ccc(-c2cscn2)cc1 +CC1CN(C)c2ccccc2CN1C(=O)c1ccnc(-n2cncn2)c1 +O=C(Nc1ccc(NCCCO)nc1)c1ccccc1F +Cc1ccc(C(=O)CCC(=O)Nc2ccnn2C2CCCCC2)s1 +Cc1c(N)cccc1-c1nnc(N2CCOCC2)s1 +Cc1ccc2[nH]nc(C(=O)N3CCN(c4nccs4)CC3)c2c1 +c1ccc(COCC2CC3OCCN(c4ncccn4)C3C2)nc1 +N#Cc1ccc(-c2noc(Cc3ccc(F)cc3)n2)nc1 +CS(=O)(=O)N1CCCC(NC(=O)NCc2ccc(F)cc2)C1 +COc1cccc(NC(=O)c2ncn(-c3ccccc3)n2)c1 +Cc1cc(C(=O)NCC(=O)N2CCCC2)sc1C +COC(=O)C1CN(C(=O)NC(C)C)CCN1C(=O)c1cccs1 +CC(Cc1ccccc1F)C(=O)N(Cc1ccco1)CC1CCCO1 +Cc1c(C(O)c2ccco2)cc2c(c1C)NC(=O)C2(C)C +Cn1cc(C(C)(O)CNC(=O)NCc2cc(F)cc(F)c2)cn1 +Cc1ccc(C(CNC(=O)C(C)C)OCCO)cc1 +CCc1c(C(=O)Nc2cc(C(=O)OC)ccc2F)cnn1C +OCc1nc2ccccc2n1CCc1ncnn1C1CCCCC1 +CCCCN(C)S(=O)(=O)N1CCN(Cc2noc(C)n2)CC1 +CCN(CCO)C(=O)c1ccccc1SCc1cccs1 +CCCCC(NC(N)=O)C(=O)Nc1ccc(N2CCCCC2)cn1 +COc1cc(C)cc(CNC(=O)NCC2CN3CCCCC3CO2)c1 +O=C(Nc1nnc(C2CCCO2)o1)c1ccc2c(c1)CCCC2 +CC1C(=O)N(c2cccc3ccccc23)CCN1C(=O)C1CCC1 +COc1ccc(N(C)C(=O)CCOC(C)C)cn1 +CCOC1CCN(C(=O)CN(C)c2ncnc3[nH]cnc23)CC1 +CCc1nnsc1C(=O)Nc1cccc(N2CCNC2=O)c1 +Cc1ccc(C(=O)NCC2(c3ccccc3)CC2)c(=O)[nH]1 +CC(NC(=O)Nc1ccc(C#N)cc1)C(=O)NC1CCCC1 +Cc1cc(C(=O)CSc2ncc3ccccn23)c(C)s1 +CC(=O)NCC1CCN(C(=O)NC(C)(C)C)CC1 +CC(C)C(O)C(=O)N1CCC(Cc2ccccc2)CC1 +C=C(C)Cn1c(-c2ccncc2)nc2c(N)cccc21 +OCc1cc(Cl)cc(Cl)c1OCC1CCOC1 +CNC(=O)c1nc(C(=O)N2CCN(c3ccc(F)cc3)CC2)cs1 +CCC(=O)N1CCCN(Cc2cnc(-c3cccs3)s2)CC1 +O=C(Nc1cc(N2CCCC2)ncn1)c1cnn(-c2ccccc2)n1 +CC(=O)NCCn1cnc(-c2ccccc2)c1-c1ccc(C)c(F)c1 +COc1ccccc1CNC(=O)NCC(O)c1ccccc1F +O=C(NCCNc1ncccn1)c1ccc(F)c(C(F)(F)F)c1 +Fc1ccc(-c2ncnc3c2CCN(Cc2ccco2)CC3)cc1 +CC(=O)C(C)Sc1ncc(C(F)(F)F)cc1Cl +CC1c2cccn2CCN1C(=O)c1ccc(C#CC(C)(C)O)o1 +N#Cc1ccc(C(O)Cn2cnc(C3CCC3)cc2=O)cc1 +COc1cc(C)cc2c1OCCC2Nc1cc(-n2ccnc2)ncn1 +COC(=O)c1nnc(-c2ccc(C)cc2)nc1OC +CCOC1CCCN(C(=O)C(CC(C)C)N2CCCCC2=O)C1 +CCOc1nc(COC)nc(NC2CCCC2)c1N +COc1ccc2c(c1)C(O)(CNC(=O)c1csnc1C)CCC2 +CC(NC(=O)C1CC(=O)CC1C(=O)NC(C)C(C)(C)C)C(C)(C)C +CC1(O)CCN(C(=O)CCO)CC1Cc1ccccc1 +COc1ccc(C(=O)Nc2ccc(-c3nnnn3C3CC3)cc2)cc1 +CCn1nc(C(=O)N2CCN(C)CC2C)c2ccccc2c1=O +Cc1ccc(CC2Oc3ccc(N)cc3NC2=O)cc1C +COc1ccc(OCCCn2c(=O)oc(=O)c3ccccc32)cc1 +Cc1nc(C)n(CCNC(=O)c2ccc3cccc(F)c3n2)n1 +CC(Sc1ccccc1)C(=O)N(C)Cc1ccc2c(c1)OCCO2 +O=C(CCC1CC1)NCc1ccnc(OC2CCC2)c1 +O=C(CSc1nc(=O)[nH]c2c1CCCC2)c1ccc(F)cc1 +Cc1cc(OCC(=O)Nc2ccccc2C(C)(C)C)no1 +O=C(Nc1cccnc1N1CCCCC1)C1CC2CCC1C2 +Cc1nc(C)c(C(=O)N(CCC(N)=O)Cc2ccccc2)s1 +COc1ccc(N)cc1OCC(=O)Nc1cccc(F)c1 +COc1ccc(NC(=O)NC(C)C)cc1OC1CCCC1 +Cc1cc(CN(C)C(=O)CCc2nc(-c3ccsc3)no2)no1 +Cc1occc1CN(C)C(=O)Nc1nccn(C)c1=O +O=C(CCNC(=O)NCCO)NC1CCCCC1 +Cc1cnc(NC(=O)Cc2csc(N3CCCC3=O)n2)s1 +CN(CC(=O)NCCc1ccc2c(c1)OCCO2)S(C)(=O)=O +COCCN1CC(C(=O)NCCc2ccccc2)CC1=O +CC1COCCN1C(=O)c1ccccc1N(C)c1ccccc1 +Cc1cn(CCNc2nc(C3CCCC3)nc3c2cnn3C)nn1 +Cc1ccc(C(C)N(C)C(=O)c2cc(Br)c[nH]2)s1 +CCOc1ccccc1NC(=O)CSc1ccccn1 +COCC(NC(=O)c1csc(-c2ccoc2)n1)C(N)=O +CN(C)C(=O)C1CCN(C(=O)Nc2cc(Cl)ccc2F)CC1 +CCC1CN(C(=O)CCN2Cc3ccccc3C2=O)CCC1(C)O +CNc1nc2c(c(=O)n(C)c(=O)n2C)n1CC(O)c1ccccc1 +Cc1ccn2c(C(C)C#N)c(-c3cccnc3)nc2c1 +COC(=O)C(C)NC(=O)CCc1cc(F)ccc1Br +CC1CCN(C(=O)CC(C#N)C(=O)N2CCC(C)CC2)CC1 +Cn1cc(S(=O)(=O)N2CCc3ccccc3C2C(N)=O)cn1 +CCc1ccc(CNC(=O)C2c3ccccc3CC(=O)N2CC)cc1 +Cc1cc(F)ccc1NC(=O)c1cc2ncccn2n1 +O=C(NCC1CC1)C1CCCN(C(=O)c2cnns2)C1 +CN(Cc1ncnn1C)C(=O)NCCc1ccc(-n2cccn2)cc1 +CN(C)c1ncnc(NCCc2cccs2)c1N +CN(C)C(=O)c1ccc(-c2cc(O)cc(C(F)(F)F)c2)cc1 +Cc1nc(-c2ccc(NC(C(N)=O)c3ccccc3)cc2)cs1 +CCCCS(=O)(=O)N1CCCC1c1nc(C)no1 +CCCC(NC(N)=O)C(=O)Nc1ccc(F)c(Cl)c1 +CCCc1n[nH]c(C2CN(C(=O)CCc3cccnc3)CCO2)n1 +O=C(NCCc1ccccn1)c1cc(-c2ccc(Cl)cc2)[nH]n1 +O=C1NC(O)(C(F)(F)F)CC(O)(C(F)(F)F)N1 +CC(=O)c1cccc(S(=O)(=O)NCCC(=O)NC2CCCC2)c1 +COc1ccc(-c2noc(CN(C)S(C)(=O)=O)n2)cc1 +COc1ccc(OC)c(CC(C#N)C(=O)NC2CCCC2)c1 +Cc1ccc(F)c(CN(CCC#N)Cc2ccccn2)c1 +CC(NC(=O)CNC(=O)NC1CCCCC1)c1nnc2ccccn12 +CC(C)(C)Oc1ccc(C(=O)NC(C#N)C2CCOC2)cc1 +CN(C)c1ncc(C(=O)N(C)C2CCCCC2)c(N)n1 +Cc1cc(C)cc(OCC(=O)NCC2COc3ccccc3O2)c1 +COC(=O)CCc1cc(Br)ccc1OC +C#CCSc1nnc(-c2cn(C)nc2OC)n1C +COc1cc(C(=O)NCc2ccccc2)nc2ccccc12 +CCC1CCCC(NC(=O)Cc2c(C)nc(C)[nH]c2=O)C1 +Cc1cc(CN(C)C(=O)NCc2ccc3c(c2)OCO3)no1 +CCOc1cc(OC)ccc1CNc1cc(C)on1 +COCc1ccccc1NC(=O)CN(C)c1ncnc2[nH]cnc12 +CCN1C(=O)c2ccccc2NC1c1ccc(O)c(OC)c1 +CCCn1nc(C(=O)NCc2ccnc(OC3CCC3)c2)ccc1=O +Cc1nc(C2(NC(=O)C3CC3(Cl)Cl)CCCC2)no1 +Cc1nc(-c2c[nH]c(C(=O)N(C)CCC#N)c2)cs1 +C=CCOc1cccc(NCC(=O)N2CCCCC2)c1 +N#Cc1ccc(NC(=O)Cn2c(=O)cnc3ccccc32)cc1Cl +CCCc1cc(C(=O)NCc2cccnc2OC)sc1C +Cc1cc(CNC(=O)c2ccc(-n3cnnn3)cc2)ccc1F +Nc1nc(CNC(=O)Nc2cccc3cccnc23)n[nH]1 +Cc1cc(C)c2cc3c(nc2c1)OC(=O)N(CCN1CCOCC1)C3 +[H]N=c1n(CC)c2ccccc2n1CC(=O)c1ccc(C)cc1 +O=C(Nc1ccc(N2CCCS2(=O)=O)cc1)c1ccncc1 +CCCC(C)NS(=O)(=O)Cc1cccc(N)c1 +Cc1cccc(OCCN2c3ccc(S(N)(=O)=O)cc3CC2C)c1 +O=C1CC(C(=O)N2Cc3cc4ccccc4nc3C2)CO1 +CCc1cc(C(=O)Nc2cc(F)cc(F)c2)no1 +CCCNC(=O)CNC(=O)Cc1c(C)nn(-c2ccccc2)c1C +O=C(Nc1ccc(Cl)cn1)c1cnn(-c2ccccc2)n1 +O=C(NCCc1ccsc1)NCC1CCOC1 +CCOc1ccc(NC(=O)c2cnn(-c3ccncc3)c2C)cc1F +Cc1nc(NC(=O)c2cc3cnn(C)c3nc2N)sc1C +CC(C)OC(=O)CCNC(=O)Nc1ccc(F)cc1C#N +CCOC(=O)c1csc(C(=O)NCc2ccccc2)n1 +CCC(=O)N1CCCC(C(=O)NC2(c3cccc(Cl)c3)CC2)C1 +COc1cccc(OCCn2c(CCO)nc3ccccc32)c1 +CCC(=O)Nc1ccc(-n2cnc(C(=O)NCC(C)C)c2)nc1 +NC(=O)C1CCN(C(=O)c2ccc(Oc3ccccc3)nc2)CC1 +CC(c1cc2ccccc2o1)N(C)C(=O)CSc1nncn1C +N#Cc1ccc(-c2noc(-c3ccc(C(=O)c4cc[nH]c4)cc3)n2)nc1 +Cc1nn(-c2ncc(Cl)cc2Cl)c(N)c1C +COC(=O)c1ncn(CC(=O)c2[nH]c(C)c(C(C)=O)c2C)n1 +Cc1ccc(C(=O)Nc2nc3c(c(=O)[nH]2)CCCC3)cc1 +CC(C)CN1CCOc2ccc(C(=O)C(C)N)cc21 +CC1c2ccsc2CCN1C(=O)c1cc(Cl)c2c(c1)OCCO2 +COCCCC1(CO)CCCN(C(=O)C(C)(C)OC)C1 +Cc1ccccc1N1CC2(CCN(C(=O)c3ccccc3)C2)CC1=O +CCn1cnc2c(nnc3c(-c4ccc(F)cc4)cnn32)c1=O +Cc1ccc(C)c2[nH]c(=O)c(CCNC(=O)C(C)C)cc12 +O=C(N1CCCCC1)N1CCN(Cc2nc3ccccc3o2)CC1 +Cn1c(C(=O)Nc2cccc(-c3nc4ccccc4[nH]3)c2)cccc1=O +Cc1[nH]ncc1-c1nn2c(-c3cccs3)nnc2s1 +CCn1cnnc1C1CCN(c2ncccc2C(=O)OC(C)C)CC1 +CC(=O)Nc1ccccc1OCC(=O)N(CC(C)C)C1CC1 +CC(O)CCN(C)C(=O)Nc1cnn(-c2ccccc2F)c1 +Cc1nn(-c2ccc(Cl)cc2Cl)c(C)c1CC(N)=O +CN(C(=O)C1CCN(S(C)(=O)=O)CC1)C1(C#N)CCC1 +CC(C)(O)C#Cc1ccc(C(=O)NC2CCCCC2)cc1 +CCn1c(SC2CCCC2)nnc1N1CCOCC1 +O=C(NCC(=O)N1CCCC1)c1cnn2c1OCCC2 +CC(C)OC(=O)c1nnn(C(C)C(=O)OC(C)C)c1N +Cc1cc(NC(=O)CNc2c(C)cccc2C(N)=O)n(C)n1 +O=C(Cn1c(CO)nc2ccccc21)Nc1ccccn1 +CNC(=O)c1cc(=O)c(OCc2ccccc2)cn1C +COc1ccccc1-c1cn2nc(C(C)C)sc2n1 +CC(NC(=O)Nc1cccn(C)c1=O)c1cccc(-n2ccnc2)c1 +Cc1nnc2n1CC(NC(=O)c1cc(=O)[nH]c3ccccc13)CC2 +CCOC1CCCN(C(=O)Nc2ccc(C(C)=O)c(C)c2)C1 +Cc1cc(C(F)(F)F)c(C#N)c(SC(C)C)n1 +OC1(CNCc2ccccc2)CCc2ccccc21 +COc1ccc(C(C)(C)CNC(=O)NCC2CC2)cc1 +O=C(Cc1ccc2c(c1)OCCO2)NC1CCOc2ccccc21 +CCCN1Cc2cccc(C(=O)Nc3ccc(OC)cc3)c2C1=O +CC(C)NC(=O)CSc1c(Cl)cccc1Cl +Cc1cnc(C(=O)OCCOc2ccc(S(N)(=O)=O)cc2)cn1 +C=CC(CC(=O)Nc1cncnc1N(C)C)c1ccccc1 +NC(=O)c1ccc(CS(=O)(=O)c2ccccc2Cl)cc1 +CC1(C(N)=O)CN(C(=O)c2cccc(Cl)c2)CCO1 +Cc1nnc(NC(=O)Cc2c(C)nn(CC(C)C)c2C)s1 +CC(C)CCC(C)NC(=O)C1CCN(C(=O)c2ccsc2)CC1 +CC(C)OC(=O)CNC(=O)Nc1ccn(-c2ncccc2Cl)n1 +COc1ccc(-c2[nH]c3ccccc3c(=O)c2O)cc1 +O=C(NCc1cc2ccccc2o1)c1ccnc2ccccc12 +COc1ccccc1OCCNC(=O)c1c[nH]c(=O)c2ccn(C)c12 +Cc1ccc(NC(=O)c2cc(C3CC3)[nH]n2)c2cccnc12 +CC(C)c1noc(CCNC(=O)Nc2ccc(-n3cnnn3)cc2)n1 +Cc1oc(C)c(C(=O)N2CCC(C(N)=O)C2)c1C +O=C(C1CCCC1)N1CCN(Cc2nncn2-c2ccccc2)CC1 +CN(CC1CCCCC1)C(=O)CNC1=NS(=O)(=O)c2ccccc21 +CC(=O)c1ccc(NC(=O)c2csc(-c3ncccn3)n2)cc1C +CN(CC(=O)N1CCNCC1)C(=O)c1c(Cl)cccc1Cl +COc1cc(-c2nocc2C#N)cc(OC)c1OC +CCOc1ccc(OCCn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 +Cc1noc2nc(-c3ccccc3F)cc(C(=O)N3CCOCC3)c12 +Cc1nnc(C2CCN(Cc3cc4ccccc4o3)C2)o1 +COc1ccc(C(=O)Nc2nnc3n2CCS3)cc1 +COC(=O)CC(NC(=O)c1cccc(Cl)c1Cl)C1CC1 +CN1C(=O)C(Cc2ccc3c(c2)OCO3)Oc2cc(N)ccc21 +CCC(C)C(=O)Nc1cc(Cl)ccc1C(=O)NC +CCOC(=O)c1c(C)nc(N)nc1-c1ccc(OC(C)C)cc1 +CCC(C)NC(=O)c1cccc(-c2nnnn2C)c1 +COCc1cccc(NC(=O)c2cc3ccccn3n2)c1 +Cc1c(C(=O)N2CC(c3ccccc3Cl)OCC2(C)C)cnn1C +Cc1csc(CCNCc2c[nH]nc2C(C)(C)C)n1 +O=C(NCCc1ccc(OC(F)(F)F)cc1)c1ccc2[nH]cnc2c1 +O=C(NC1CCCC1O)c1cc(-c2ccccn2)ccc1Cl +CC(Sc1ccccc1Cl)C(=O)NCC1CCCO1 +CCc1nn(C)cc1C(=O)N1CCOCC1CC(=O)c1cccs1 +Cc1nc2n(n1)CCCC2NC(=O)CCc1cccc(Cl)c1 +Nc1nc(N)nc(COc2ccc(Cc3ccccc3)cc2)n1 +COCc1cc(=O)[nH]c2cc(NC(=O)C3CCC3)ccc12 +COc1cccc(CN(C)C(=O)c2nc(SC)ncc2Cl)c1 +CC(NC(=O)CN1CCN(c2ccccc2)CC1)C(=O)N(C)C +CCn1c(N)c(C(=O)CN(C)Cc2ccc(C)s2)c(=O)[nH]c1=O +CCc1ccccc1NC(=O)c1onc(-c2ccccc2)c1N +c1csc(Cc2n[nH]c(SCCn3cccn3)n2)c1 +Cn1ccnc1S(=O)(=O)Cc1cc(Cl)c2c(c1)OCCO2 +CC(C)(C)c1csc(C2CCN(C(=O)Cc3ccc[nH]3)CC2)n1 +O=C(OCC#Cc1ccccc1)c1ccc(=O)[nH]c1 +CCC1CN(C(=O)c2ccc(F)cc2)CCC1CC(=O)NCCO +O=C(c1ccc(Cn2ccccc2=O)o1)N1CCOC2CCCCC21 +CCN(CC)C(=O)CCC(=O)N1CCCc2c(Cl)ccc(F)c21 +O=C(COc1cccc(CO)c1)Nc1ccccn1 +COCCCCNC(=O)N1CCN(c2nccs2)CC1 +Cc1cc(S(N)(=O)=O)c(C)c(C)c1OCCC(C)C +O=C(Nc1ccc2nc(CO)[nH]c2c1)c1ccc(Cl)cc1 +Fc1cnc(N2CCOC3C(OCc4ccccn4)CCC32)nc1 +Cc1cccc2c1N(C(=O)c1cccc3[nH]c(=O)oc13)CC2 +CCCc1nnc(SCC(=O)Nc2cccc(OC)c2)o1 +O=C(NC1(C(=O)N2CCCC2)CCCC1)c1cc2cccn2cn1 +O=C(OCC(=O)N1CCOCC1)c1occc1-c1ccccc1 +O=C(NCc1cccs1)c1cc(F)ccc1-n1cnnn1 +CCCn1ncc(C(=O)NCC2COc3c(cccc3OC)C2)c1C +COC(=O)c1oc(CN2CCN(C(=O)C3CCCO3)CC2)cc1C +CC1(C)COC(c2cc3c(cc2Br)OCO3)OC1 +Cc1ccc(OCCCNS(=O)(=O)N2CCOCC2)cc1 +Fc1ccc(C#CCN2CCOCC2C2CC2)cc1 +CCCn1ccnc1SC(C)C(=O)c1ccc(NC(C)=O)cc1 +COc1cccc(CNc2nnc(-c3cccs3)o2)c1 +COc1ccc(OCCS(=O)(=O)N2c3ccccc3CC2C)cc1 +Cc1ccccc1S(=O)(=O)Nc1ccc(F)c(N)c1 +COCCOc1cccc(C(=O)Nc2cccc(C)c2C(N)=O)c1 +CCOc1c(Cl)cccc1NC(=O)c1cnn(C)c1 +CCc1onc(C)c1NC(=O)c1cn(Cc2ccccc2)nn1 +CC(Oc1cccc(C(C)C)c1)C(=O)n1ccnc1 +CCOC1CCCN(C(=O)c2cc(Cl)ccc2N)C1 +O=C(Nc1ccc2c(c1)COC2)c1ccc(=O)n(Cc2ccccc2)n1 +CC(NC(=O)NC(c1ccccc1)c1ccncc1)C1CCCO1 +O=C(c1ccc(F)c(Cl)c1)N1CCOCC1C1CC1 +CCN1CCOC(CC(=O)Nc2cc(OC)cc(OC)c2)C1=O +O=C(Nc1ccc(-c2nc3cccnc3s2)cc1)C1CCCO1 +COCc1nc2ccccc2c(C)c1C(=O)OCC(=O)NC1CC1 +COC(=O)c1cc(C(=O)CSc2nc(C)cc(C)n2)ccc1O +COc1cc(CCNC(=O)C2(C#N)CCC2)ccc1O +Cc1cc(C(=O)NCc2ccc(C)o2)c2ccccc2n1 +COC(=O)c1cnn(-c2ccc(OC)c(OC)c2)c1N +CC1CCCCN1S(=O)(=O)NCCOCCO +Cc1ccc(S(=O)(=O)C(C)C(=O)NC2CCCCC2C)cc1 +CCCOc1c(Cl)cc(C(=O)N2CCCC(C)C2)cc1OC +COCCN(Cc1ccco1)C(=O)c1cc2cc(F)ccc2[nH]1 +CCOc1ccc(C(=O)NCC2COC3(CCCCC3)O2)cc1 +COc1ccc(O)c(C(=O)CC2OC(=O)c3ccccc32)c1 +Cc1cc(S(=O)(=O)N(C)c2cccc3ncccc23)c(C)s1 +CCCNC(=O)C(C)OC(=O)c1ccc(OC)nc1 +CCC(C)(CCO)NC(=O)c1ccc2cc[nH]c2c1 +C#Cc1cccc(N(CC(=O)NC)C(=O)c2ccc(F)nc2)c1 +CNc1ccc(Cl)c(Cn2c(C)c(C)sc2=O)n1 +COCCOc1ccc(NC(=O)N2CCCC(C)C2)cc1 +CC(C)n1ccc(C(=O)Nc2nc3cc4c(cc3s2)OCCO4)n1 +Cc1cc(CS(=O)(=O)c2nnc(C)n2-c2ccccc2C)no1 +CC(=O)c1cccc(OC(=O)CCc2nc(C(C)C)no2)c1 +CN(C)C(=O)Cn1cc2c(n1)C(CNCc1ccco1)OCC2 +COc1ccc(C(=O)NCC(=O)NC2CCCCC2)cc1 +O=C(Nc1ccccc1OCc1cscn1)c1cccs1 +c1ccc(-c2csc(CN3CCCC(N4CCOCC4)C3)n2)cc1 +COC(=O)c1ccc(-c2nc3sccc3c(=O)[nH]2)cc1 +CCc1ccc(C(=O)N(CC)CC(C)C#N)s1 +COc1ccc(S(=O)(=O)N(C)CC2CCCC2)cc1C(N)=O +O=C(Cc1cccc2ccccc12)NCc1ccoc1 +CCOC(=O)C1CCN(C(=O)CNc2ccc(C)c(C)c2)CC1 +CCOCCCC(=O)Nc1cc(Cl)ccc1N +CC(NC(=O)Cc1ccccc1F)c1ccc(-n2ccnc2)cc1 +COC(=O)c1ccc(Cn2c(C)cc(=O)c3cc(C)cc(C)c32)o1 +Cc1cc(=O)c(C(=O)NCC2CCCO2)nn1-c1ccc(Cl)cc1 +Nc1cccc2c(S(=O)(=O)c3cccc4ccccc34)n[nH]c12 +COC(=O)c1cccn1C1CCN(C(=O)c2cccc(C)n2)CC1 +O=C(c1ccncc1)c1nncn1-c1ccccc1 +CCc1onc(C)c1NC(=O)NCc1cnn(C)c1C +CCOCCCNC(=O)c1cc(-c2ccc3c(c2)OCO3)on1 +CS(=O)(=O)NC1CCCN(C(=O)C2CC=CCC2)C1 +C=CCN(CC=C)C(=O)c1cnc(-c2ccccc2)nc1N +O=C(NC(Cc1ccccc1)C(=O)N1CCCC1)C1CC=CCC1 +CCOC(=O)COc1ccc2c(C)c(C)c(=O)oc2c1 +COc1ccc(N)cc1-c1nnc(N2CCCCC2)o1 +CC1CC(C)CN(S(=O)(=O)c2c(F)cccc2F)C1 +COCCNC(=O)Nc1ccccc1-n1nc(C)cc1C +Nc1nc(N)nc(-c2ccc(Oc3ccccc3N)cc2)n1 +COCC(C)(O)CNC(=O)Cn1c(=O)oc2ccccc21 +CCN(CC)C(=O)C1CCCN1C(=O)Cc1cccc(OC)c1 +Cc1c(Cl)c(CN(C)Cc2cn[nH]c2)nc2ccccc12 +Cn1c(=O)c(C(=O)N2CCc3ccccc3C2)nc2ccccc21 +Cc1noc(C2CCN(C(=O)C3COCCO3)CC2)n1 +NC(=O)N1CCCN(C(=O)c2ccc(F)cc2)CC1 +Cc1cccc(C2CCCN2c2ccc3nnnn3n2)c1 +COC(=O)C(C)CC(=O)NC1CCCCC1C(F)(F)F +Cc1nc(C(=O)N(Cc2cncs2)C2CC2)cs1 +CC(C)NC(=O)Nc1ccccc1C(=O)NCCO +CC(c1nccs1)N(C)c1nc2nonc2nc1N(C)C +CC(Cc1cccc(Cl)c1)C(=O)N1CCN2C(=O)NCC2C1 +CCCCNC(=O)c1cnc(-c2ccccc2OC)nc1N +ClC1(Cl)CC1CSc1nnc(-c2ccccn2)o1 +Cc1cc(C)c(C(=O)N2CCN(c3ncccn3)CC2)c(C)c1 +CC(NC(=O)Cc1c(F)cccc1F)c1ccc(-n2cncn2)cc1 +O=C(COC(=O)c1ccccc1)NCc1ccccc1 +Cc1nc(-c2cc(C(=O)NC(C)Cc3cccs3)n(C)c2)cs1 +CCNc1nnc(-c2c(C)oc3c2CCCC3)s1 +CCOC1CCN(C(=O)c2cc(C3CC3)nn2-c2ccccc2)CC1 +CCCC(C)NC(=O)Nc1ccccc1S(C)(=O)=O +COc1cc(C)c(Nc2nccc(C(F)(F)F)n2)cc1OC +Cc1n[nH]c(N)c1C(=O)Nc1c(Cl)cc(Cl)cc1Cl +Cn1cc(CNc2cccc(O)c2)c(-c2cccnc2)n1 +Cc1cccc(C)c1-n1nc(CC#N)c(=O)cc1C +CCCOc1cccc(NC(=O)N2CCCC2c2nncn2C)c1 +Cc1cc(C(=O)N2CCN(Cc3nnc4n3CCCCC4)CC2)on1 +CCCCNC(=O)C(C)Sc1nnc(-c2ccc(C)cc2)n1N +COCC(=O)N1CCN(Cc2cnc3ccccn23)CC1 +O=C(COC1CCCCC1)N1CCCN(C(=O)c2ccncc2)CC1 +N#CC1CC(=O)N(c2ccccc2C(F)(F)F)C1 +CCSc1nnc(NC(=O)CC(C)n2ccc(C)n2)s1 +CS(=O)(=O)N1CCc2cc(C(=O)NCCC3=CCCCC3)ccc21 +Cc1cc(C(=O)NCc2csc(=O)[nH]2)[nH]c(=O)n1 +Cc1ccc(C#N)c(Oc2ccc(N)cc2Cl)c1 +COc1ccc(F)cc1NC(=O)c1ccnc(SC)c1 +CC1CN(CCC(=O)Nc2ccccc2C#N)CC(C)O1 +N#Cc1ccsc1C(=O)NCC(O)c1cccc(OC(F)F)c1 +CC(C)(C)C(=O)CN1c2cccc3cccc(c23)S1(=O)=O +Cc1c(C(=O)OCCCNC(N)=O)sc2ccc(F)cc12 +CCC(CC)NC(=O)COc1ccc(C)nc1N +COC(=O)C(c1ccccc1C(F)(F)F)N(C)C +O=C(NCc1ccoc1)NC1CCSc2ccccc21 +Cc1cc(C(=O)NCCSc2ccccc2)ccc1-n1cnnn1 +COc1ccc(C(=O)NC(C(=O)NC(C)C(C)C)C(C)C)cc1 +CC(NC(=O)NCc1ccccn1)c1cccc(OC(F)F)c1 +Cc1cc(SCc2c(C)noc2C)c2ccccc2n1 +Nc1nonc1C(=O)NCc1ccc(F)cc1F +CC=CCOC(=O)CCNC(=O)c1cccs1 +O=C(NCCO)c1cnn(-c2ccccc2F)c1-n1cccc1 +c1ccc2c(c1)ncn2Cc1ccc2c(c1)OCO2 +O=c1cc(C2NCCc3cccc(Cl)c32)cc[nH]1 +Cc1ccc(C2COCCN2C(=O)Cc2ccc[nH]2)o1 +Fc1ccc(OCCc2nc3c(s2)CCN3)c(Cl)c1 +N#Cc1cccc(NC(=O)c2cccc(-c3ccoc3)c2)c1 +CCCOc1ccccc1-n1nnc(CO)c1C(F)(F)F +CC(=O)NC(CC(F)(F)F)c1ccc(Cl)cc1 +O=C(c1ccc(NCCCC2CCCC2)nc1)N1CCCC1 +N#Cc1c(N)cccc1SC(F)(F)C(F)(F)F +CCC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc1nnc(C)s1 +COc1ccc(C(=O)OCC(=O)Nc2cc(C)on2)c2ccccc12 +CCN(Cc1cccs1)C(=O)CSc1nnc(NC)s1 +CCC(CC)NC(=O)CSc1nnnn1C1CC1 +Cc1cccc(NC(=O)NCCNC(=O)c2cccnc2)c1Cl +CC1CN(Cc2ccccc2)CCC1N1CCOCC1 +Cc1ccc2c(c1)N(CC(=O)Nc1cccc(F)c1C)C(=O)CO2 +OCCN(Cc1ccccn1)Cc1ccccc1Br +O=C(NCc1ccccc1)c1ccc(-c2ccc(F)cc2)nc1 +Cc1nnc(SCc2ccc(C(=O)N3CCOCC3)cc2)s1 +COc1ccc(F)cc1-c1c(N)n[nH]c1-c1ccccc1 +Cc1ccc(C(=O)N2CCCC(CNC(N)=O)C2)c(=O)[nH]1 +CCCCN(CC(N)=O)C(=O)c1cc2ccccc2n1C +CCc1n[nH]c(SCC(=O)N(CC)CCC#N)n1 +N#CCc1ccc(NC(=O)NCc2cn(-c3ccccc3)nn2)cc1 +O=C(Nc1nccs1)c1cccnc1N1CCOCC1 +CC(=O)Nc1ccc(NCCOc2ccc(F)cc2)cc1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCCCCC1c1ccco1 +CN(C)C(=O)CNc1ccccc1C(=O)Nc1ccc(F)cc1Cl +CC(NC(=O)Nc1ccn(Cc2ccccc2)n1)c1ccncc1 +CC(=O)N1CCN(C(=O)COc2ccc(Cl)c3cccnc23)CC1 +CCOc1cccc(NC(=O)NCc2ccccc2)c1 +Cc1cc(CN(C)S(=O)(=O)N2CC(C)OC(C)C2)no1 +Cc1ccc(NC(=O)NC2CC(=O)N(c3cccc(F)c3)C2)c(C)c1 +CCCCNC(=O)C(N)c1ccc(C(=O)OC)cc1 +O=C1CC2(CCN(S(=O)(=O)c3c[nH]cn3)C2)Oc2ccccc21 +COc1cccc(NC(=O)Cc2csc(-n3nc(C)cc3C)n2)c1 +O=C(Cn1cnc2sc3c(c2c1=O)CCC3)N1CCCCC1 +COc1ccc(CNc2cnn(C)c(=O)c2Cl)cc1 +Cc1cc(C)n(CCC(=O)N2CCN(C3CCCC3O)CC2)n1 +COc1ccc(OCCNC(=O)c2cnc(C3CCCO3)s2)cc1 +Cc1ccc(NC(=O)c2cc(C)n(C3CC3)c2C)c(C)c1 +CCC(NC(=O)c1cc(C(C)C)[nH]n1)c1cccc(Cl)c1 +CCn1c(SCC(=O)N(C)C)nnc1-c1ccccc1 +Cc1nn(C)c(C)c1OCC(=O)Nc1cccc(-c2ncon2)c1 +c1ccc(-n2c(-c3ccncc3)nc3cccnc32)cc1 +CN(Cc1cccc(F)c1)C(=O)c1cn(Cc2ccccc2)nn1 +CC(=O)c1cccc(S(=O)(=O)NCc2ccccc2Cl)c1 +O=C1NCCN(C(=O)CCc2ccccc2F)C1c1ccccc1 +Cc1csc(N2CCN(Cc3cccc(OCC(N)=O)c3)CC2)n1 +Cc1ccc2[nH]c(=O)c(CN(CC(C)C)C(=O)c3ccco3)cc2c1 +CNC(=O)c1ccc(NC(=O)c2cc(OC)c(C)c(OC)c2)cc1 +O=C(CSc1nnc2[nH]c3ccccc3n12)NCc1ccco1 +COC(=O)N(C)c1ccc(NC(=O)NCc2ccccc2Cl)cc1 +NC(=O)c1ccccc1Oc1ccc(N)c(C(F)(F)F)c1 +Cc1ccc2cccc(OCC(=O)NCc3cccs3)c2n1 +Cc1ccc(-c2cc(C(=O)N3CCCC3Cn3cccn3)on2)cc1 +N#CC(C(=O)CCc1ccc(F)cc1)c1ccccn1 +Cc1oc2ncnc(NCc3cccc(Cn4cncn4)c3)c2c1C +NC(=O)N1CCCC(C(=O)N2CCN(c3nccs3)CC2)C1 +Cc1cc(C)cc(OCCN(C)C(C)c2nc(N)nc(N(C)C)n2)c1 +CCCS(=O)(=O)N(C)C(C#N)c1ccc(C(C)C)cc1 +NC(=O)c1cccc(-c2nc3ccc(N)cc3o2)c1 +O=C(NCCNc1ncnc2[nH]cnc12)c1ccoc1 +CCN(CCC#N)C(=O)CSc1nc2ccccc2n1C +COc1ccccc1C(NC(=O)CCC1CCCO1)c1ccccn1 +CSc1ncccc1C(=O)Nc1cc(C(=O)N(C)C)cn(C)c1=O +COC(=O)CCCN1CCOc2ccc(F)cc21 +Cc1nn(CC(=O)NC(C)(C)C)c(C)c1S(=O)(=O)NC(C)(C)C +CC(C)c1cc(C(=O)Nc2nnc(-c3ccsc3)s2)n[nH]1 +Cc1nn2ccccc2c1C(=O)NCCc1cccs1 +Cc1cc(CCNC(=O)Nc2cccs2)on1 +Fc1ccc(F)c(-c2nn3c(C4CC4)nnc3s2)c1 +Cn1ccc2ccn(CC(=O)Nc3ccc4c(c3)OCO4)c(=O)c21 +Cc1noc(C(C)N2CCN(Cc3nnc(C4CC4)n3C)CC2)n1 +Cc1noc2ncc(C(=O)N3CCCC3c3ccc(C(C)C)cc3)cc12 +Cc1ccc(C(NC(=O)c2ccn(C)c(=O)c2)C2CC2)cc1 +CC(O)c1nc2ccccc2n1CCCOc1ccccc1 +O=C(CC1CCCCC1)N1CCN(C(=O)c2ccncc2F)CC1 +O=C(NCc1ccc(F)cc1)C1CCN(c2ncccn2)C1 +N#Cc1cnn(-c2cccc(C(=O)Nc3ccccc3C(N)=O)c2)c1N +O=C(Nc1cccc(-n2cnnn2)c1)C1CCCC1 +O=C(NCCc1ccccc1)C1CCC(=O)N1Cc1ccc(F)cc1 +COc1ccccc1NC(=O)CCNC(=O)c1c[nH]c2cccnc12 +CCOC(=O)c1cn(CC)c2ccc(NC(=O)CC)cc2c1=O +Cn1cnc(S(=O)(=O)NCC(=O)Nc2cccc(Cl)c2)c1 +O=C(Cn1nc(-c2ccco2)ccc1=O)OCc1ccccc1 +O=C(Cc1cccc(F)c1)NC1CCN(c2c(F)cccc2F)C1 +CC(C)(C)C(=O)Nc1ccc(NC(=O)c2ccco2)cc1 +CCCn1c(=O)[nH]c(=O)c2c(C(=O)NCC3CC3)cc(C3CC3)nc21 +OCCN(c1ncnc2ccsc12)C1CCCCC1 +O=c1ccccn1CCCCNS(=O)(=O)c1ccc2c(c1)CCO2 +CS(=O)(=O)c1ccc(Cl)c(C(=O)NCC2CC2)c1 +CN(CC(=O)NC(C)(C)C)S(=O)(=O)c1ccc(Cl)cc1F +O=C(CSc1nc(=O)[nH]c2c1CCC2)NC1CCCCC1 +Cc1c(C(=O)NC(C)c2ccco2)cnn1-c1ccccc1 +CCOc1ccc(NC(=O)OCC(C)C)cc1CO +CCOC(=O)c1sc(-c2ccc(N)cn2)nc1C +CC1CN(C(=O)c2ccc3c(c2)C(=O)c2ccccc2-3)CC(C)O1 +CNc1ccc(C)cc1C(=O)NCCCS(N)(=O)=O +CC(C)C1=NC(=O)C2(CCN(c3nc(N)nc4[nH]ncc34)CC2)N1 +CCOc1cc2c(cc1OCC)-c1c(c(=O)c1=O)C(C)C2 +Cc1cc(NC(=O)NC2CCN(c3ncccn3)CC2)no1 +CC(=O)N1CCC(C(=O)OCC2CC=CCC2C)CC1 +CCn1nc(C)cc1C(=O)Nc1nnc(-c2ccc(F)cc2)o1 +O=C(Nc1ccc(-n2cncn2)nc1)C1CCCCC1 +COc1ccc(C(=O)N2CCc3cc(F)ccc3C2C)nn1 +COC(=O)C1(NC(=O)c2csc3ccccc23)CC1 +Cc1noc(C)c1CNc1nc(-c2ccccc2)ns1 +COC(=O)Cc1cc(=O)[nH]c(-c2ccc(OC)cc2)n1 +Cc1cccc(Sc2nccnc2SCC(=O)NC(C)C)c1 +Cc1ccc(C(=O)Nc2cccc(CNC(=O)NCCCO)c2)cc1 +Cc1cccc(-c2nnc3c(N)c(Cl)ccn23)c1 +O=C1CC(c2ccccc2)S(=O)c2ccccc2N1 +NC(=O)C1CN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CCO1 +Cc1cc2c(cc1C)N(CCCC#N)C(=O)C(C)N2 +N#Cc1nc(-c2ccco2)oc1N1CCN(C(=O)C2CC=CC2)CC1 +Cc1noc2nc(-c3ccccc3F)cc(C(N)=O)c12 +COc1ccc(C(=O)Nc2cc(C(F)(F)F)ccc2F)cc1OC +O=C(OCCN1CCCC1=O)c1cccc(Cl)c1 +CNC(=O)c1cccc(CNc2ccc(Br)cc2C#N)c1 +Cc1nc(C)c(C(=O)Nc2cc(N3CCC(C)CC3)ncn2)s1 +N#CCc1ccc(NC(=O)c2ccccc2CN2CCOCC2)cc1 +Cc1nnc(-c2ccccc2CCOCc2ccccc2)o1 +CCOCC1(CNCc2cc(=O)c3cc(C)ccc3[nH]2)CC1 +COc1ccc(C2CCCN2C(=O)CNC(=O)c2ccccc2)cc1 +Cc1cccc(C(=O)N2CCCC2)c1NC(=O)c1scnc1C +Cc1cc(C)c2c(C#N)cn(Cc3ccccc3)c2n1 +CCCNC(=O)CCc1nc(-c2ccccc2OC)no1 +CC(C#N)Cn1ccc2cc(C(C)C)ccc2c1=O +CN(CCOCC1CC1)C(=O)Cc1c[nH]c2ccccc12 +CC(NC(=O)Cc1ccc(Cl)cc1Cl)C(=O)N1CCOCC1 +CC1CC(C)CN(C(=O)c2noc3c2COc2ccccc2-3)C1 +COc1ccc(C(=O)NCCc2nccs2)cc1N +Cc1c(C(=O)NC2CCCOC2)sc2ncn(C)c(=O)c12 +COc1ccc(CC2CN(C(=O)c3ccsc3)CCC2OC)cc1 +Cc1cnn(CCC(=O)Nc2ccc(Br)cc2Cl)c1 +CCOc1cccc(-c2nc(C(=O)NCc3ccco3)cs2)c1 +CCN1C(=O)Cc2cc(NC(=O)c3cccnc3)ccc21 +CC(Cc1cccc(Cl)c1)C(=O)N1CCOC(c2cnn(C)c2)C1 +CCc1nnc2n1CCN(C(C)c1nc(-c3cccs3)no1)C2 +Cc1ccccc1-n1cnnc1SCCS(N)(=O)=O +Cc1ccc(C(=O)Nc2ncnc3sccc23)cc1 +Cc1cc(C)c(C(=O)NCc2cc(F)cc(C(F)(F)F)c2)c(=O)[nH]1 +Cc1occc1CN(C)C(=O)Nc1cccc(-n2nnnc2C)c1 +CCCNC(=O)Cn1nc(C)c2sc3ccccc3c2c1=O +Cc1ccc(N(CC(=O)Nc2ccccc2C)S(C)(=O)=O)cc1 +Cc1cc(C)c2[nH]c(CNC3CCNC3=O)cc(=O)c2c1 +CC(=O)N(Cc1cc2cccc(C)c2[nH]c1=O)c1ccc(C)c(C)c1 +Cc1cc(C(=O)CSc2nnc(-c3ccco3)o2)c(C)n1C(C)C +CN(Cc1nc(-c2ccncc2)no1)C(=O)Cc1ccsc1 +O=C(C1COCC2CN(c3ccccc3)CC21)N1CCC(F)CC1 +Cc1cccc(C(=O)Nc2ccc(N3CCCC(C(N)=O)C3)nc2)n1 +O=S(=O)(c1cccc(Cl)c1)N1CCC(c2ccncc2)CC1 +Cc1cccc(-c2ccc(C(=O)N3CCN(C4CC4)CC3)c(=O)[nH]2)c1 +CC(=O)NC1CCCN(C(=O)NCC2CN3CCCCC3CO2)C1 +CCOc1ccc(NC(=O)c2scnc2C)cc1CO +C#Cc1cccc(N(C(=O)CSc2nncs2)C(C)C)c1 +COc1cc(C)c(Cl)c(C)c1-c1cc(O)n[nH]1 +CCCN1C(=O)C(C)Oc2ccc(C(N)C(F)(F)F)cc21 +CCOc1ccc(OCC)c(NC(=O)c2ccccc2N)c1 +COc1ccc(F)cc1-c1c(CCCO)sc2nccn12 +CC(C)Oc1ccc(S(=O)(=O)NCCn2ccnc2)cc1 +CN(CC(=O)Nc1ccccc1)C(=O)Nc1cccnc1 +CCS(=O)(=O)c1cccc(NCC(=O)Nc2cc(C)nn2C)c1 +CCn1c(=O)[nH]c(=O)c2c(-c3ccc4ccccc4c3)ccnc21 +CCNc1nc2c([nH]1)c(=O)n(C)c(=O)n2C1CCCCC1 +Cc1nc(-c2ccc(-c3noc(-c4ccccn4)n3)cc2)cs1 +Fc1cncc(C2NCCc3cc(Cl)ccc32)c1 +C=CCn1c(=O)n(CC=C)c(=O)n(CC(=O)N2CCCCC2)c1=O +COc1ccc(-c2cncc(C(C)=O)c2)c(OC)c1OC +CC(C)c1noc(CCNC(=O)Nc2cc(F)cc(F)c2)n1 +Clc1ccccc1NCc1noc(C2COc3ccccc3O2)n1 +COc1ccc(CNC(=O)N2C3CCC2COC3)cc1 +COc1ccc(CN(C)CC(=O)c2cc(C)n(C3CC3)c2C)cc1F +CC(C)C(=O)N1CCc2cc(C(=O)N3CCCC3)ccc21 +CC(=O)N1CCC(C(=O)N2CCOC(c3ccc(F)cc3)C2)CC1 +COc1ccc(C(=O)COc2ccc(S(C)(=O)=O)cc2)cc1F +COc1cc(CNC(=O)c2n[nH]c3ccccc23)cc(OC)c1O +CC(C)(C)CC(=O)Nc1ccc(CC(=O)N2CCCC2)cc1 +COc1cc(C)sc1C(=O)Nc1ccc(CN2CCCC2=O)cc1 +COc1ccc(NC(=O)Cc2nc(Cc3ccc(C)cc3)n[nH]2)cc1 +Cc1ccc(N(C)C(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)cc1 +CCSc1cccc(NC(=O)NC2CCc3[nH]ncc3C2)c1 +CCSc1nnc(NC(=O)Cc2ccc(Cl)cc2)s1 +CCOC(=O)c1c(NC(=O)c2cc(C)oc2C)sc2c1CCCC2 +Cc1cc(F)ccc1NC(=O)c1ccc(C(N)=O)cc1 +CN(Cc1ccc(C(F)(F)F)cc1)c1cc(C#N)ccn1 +COc1cccc(NC(=O)Nc2c(-c3ccsc3)n[nH]c2C)c1 +Cc1ccc(OCC(=O)OCC(=O)NC2CC2)cc1C +Cc1noc(C2CN(C(=O)c3ccccc3F)C2)n1 +CC(NC(=O)c1cn(CC(=O)N(C)C)nn1)C1CCCCC1 +O=C1CC(c2cccc(O)c2)c2c(ccc3ccccc23)N1 +CCCCC(=O)N1CCC(Oc2cccnn2)CC1 +COc1ccc(C(=O)NCCNC(=O)NCc2ccncc2)cc1 +O=C(NCc1ccccc1Cn1cccn1)NC1CC1c1ccccc1 +CCCCN1CC(C(=O)NC(C)CCC)CC1=O +CCOc1ccc(C(C)NC(=O)c2csnn2)cc1 +CCc1cccc(C)c1NC(=O)c1csc(-c2ncccn2)n1 +CN(C)C(=O)C1(C)CN(S(C)(=O)=O)CCO1 +Cc1cc(C)n(C2CN(Cc3ccc(C4CCCCO4)s3)C2)n1 +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)N1C(C)COCC1C +CC(C)c1noc(CCCC(=O)Nc2cc(C#N)ccc2Cl)n1 +C#CC(CC)(CC)NC(=O)Nc1cnccc1C(F)(F)F +O=c1[nH]nc(SCc2ccc(F)c3cccnc23)n1C1CC1 +COCCN(C)C(=O)NCc1ccnc(OC)c1 +COc1ccc(C)cc1NC(=O)Cc1ccc(N2CCCC2=O)cc1 +CN(C)c1ncnc(Nc2ccc(C(F)(F)F)cc2)c1N +CCNC(=O)N1CCN(C(=O)c2cccc(OC3CCCC3)c2)CC1 +CC1Oc2ccccc2OC1C(=O)NCc1ccc(-n2ccnc2)cc1 +CCOc1cccc2c1C(C(O)c1ccccc1)NCC2 +COC(=O)C1CCN(C(=O)c2ccccc2Cl)CC1 +CCC(c1ccncc1)N(C)C(=O)c1cnn(Cc2ccccc2)c1 +Cc1cc2c(=O)n(CC(=O)NCC3CCCO3)ccc2s1 +COc1cc(Cl)c(C)cc1NC1CCN(C(=O)c2ccoc2)CC1 +Cc1c(C(C)NC(=O)NC2CCC(O)CC2)cnn1C +CC(C)CC(=O)N1CCc2c(nc(-c3ccncc3)nc2N(C)C)C1 +Cc1ccc(S(=O)(=O)N(CC(N)=O)C2CCCCC2)cc1 +COc1ccccc1-c1cn2nc(N)nc2cc1C +CC(C)CCn1ncc(-c2ccc(F)cc2)c(N)c1=O +Cc1cc(=O)oc2c(C)c(Oc3ncccn3)ccc12 +Cc1nc(CCNC(=O)C2CC2c2ccc(Cl)cc2)c(C)o1 +O=C(Nc1cnn(-c2cccc(C(F)(F)F)c2)c1)C1COCCO1 +CCN(C)C(=O)NCc1cccc(Br)c1 +COCC(=O)N1CCN(CCSc2ccc(C)c(C)c2)CC1 +NC(=O)c1ccc(NC(=O)c2cccc(OCC(F)F)n2)cc1 +C=CCN(CC=C)C(=O)c1cc2cc(F)ccc2[nH]1 +CSc1nnc2c(n1)OC(C)(C)Nc1ccccc1-2 +COC(=O)c1ccc(NS(=O)(=O)c2ccc(F)c(F)c2)cc1 +COc1cc(C(=O)Nc2c[nH]nc2C)cc(Cl)c1OC +NC(=O)NCc1ccc(C(=O)NC2(c3cccc(Cl)c3)CC2)cc1 +COC(=O)Nc1cccc(NC(=O)N(C)Cc2cnn(C)c2)c1 +CC1(c2nc(-c3ccccn3)no2)Oc2ccccc2NC1=O +CCCCS(=O)(=O)NCC(=O)N1CC(C)Oc2cc(F)ccc21 +CC1(Cc2ccc3c(c2)OCO3)CCCN(C(=O)N2CCOCC2)C1 +CC(C)Cc1cc(C(=O)N2CC(C)C(O)(C(C)C)C2)nc(N)n1 +C#CCOc1ccc(NC(=O)N2CCC(O)(C(F)(F)F)C2)cc1 +COC(=O)C1=C(CSc2n[nH]c(=O)n2C2CC2)CCO1 +O=C(c1ccco1)N1CCN(Cc2cn3cc(Cl)ccc3n2)CC1 +CN(C)S(=O)(=O)c1cccc(COC(=O)c2cnccn2)c1 +COc1ccc(COc2cc(C)c(N)c(C)n2)c(OC)c1 +O=C(CS(=O)(=O)c1ccc(F)cc1)NCC1CCCCC1 +O=C(c1cc(=O)n(-c2ccccc2)[nH]1)N1CCC(O)(CO)CC1 +Cc1nn(C)c(N2CCOCC2)c1CNC1CC1c1ccccc1 +COc1ccc(C)cc1-c1csc(NC(=O)CCn2cncn2)n1 +Cn1ccc2cc(-c3n[nH]c4c(N)cccc34)ccc21 +O=C(C1CCCCN1S(=O)(=O)c1ccccc1)N1CCC(O)C1 +CC(c1ccco1)N(C(=O)NCC1CCCO1)C1CC1 +COc1cc(C)c(C(=O)CNS(=O)(=O)N(C)C)cc1C +CC(C)Oc1ncccc1CNc1ccc(Br)cn1 +CCNC(=O)CN1CCN(c2ccc(F)cc2)C1=O +COCc1cc(C)nc2sc(C(=O)c3ccccc3)c(N)c12 +O=C(CNC(=O)C1CC1)Nc1ccc2ccccc2n1 +CCCCNC(=O)C1(NC(=O)c2ccc(C)nc2)CCCCC1 +CCc1ccsc1C(=O)N1CCC(C(=O)N(CC)CC)CC1 +CCOC(=O)CSc1nc(C)cc(C)c1C#N +COc1ccc(N)cc1NC(=O)CCC1CCCCC1 +CC(C)NC(=O)Nc1ccc(NC(=O)CCCn2cncn2)cc1 +CC(C)COC(=O)CN1C(=O)CSc2ccccc21 +CC(Oc1ccccc1Cl)C(=O)NCc1ccc2c(c1)OCO2 +CC(C)(CNC(=O)NCc1cccnc1OC1CCCC1)C(N)=O +COCc1noc(CCNC(=O)c2cc(C(C)C)n3ncnc3n2)n1 +COc1ccccc1-c1cc(C(=O)N2CCOCC2C)no1 +CCC(Sc1nnc2[nH]c(=O)c(C)c(C)n12)C(=O)OC +CCOC(=O)C1CN(Cc2ccccc2)CC(F)(F)C1O +COc1cccc(N(C)S(=O)(=O)C(C)C(F)(F)F)n1 +COc1ccc(S(=O)(=O)NCCc2ccoc2)cc1 +O=C(CSc1cc[nH]c(=O)n1)Nc1ccc(F)cc1 +COCc1nc(CCOc2cccc(C)c2)sc1C#N +CCCNC(=O)CNC(=O)Cc1ccc(F)c(F)c1 +CCC(C)n1ncc(C(=O)NC(C)C(=O)OC)c1C1CC1 +Cc1ncc(CNC(=O)N2CCN(C(=O)c3ccco3)CC2)s1 +COc1ccc(OC)c(CCNC(=O)N2CCOCC2C)c1 +O=C(NCc1c(F)cccc1F)C1CC(=O)N(C2CCOCC2)C1 +NC(=O)NCCC(=O)NC1CCOc2ccc(Br)cc21 +Cc1cccc(NC(=O)C2CN(C)CCO2)c1O +COc1ccc(OC)c(NCC(O)c2ccccc2C)c1 +CN(C)C(=O)CN(C)C(=O)C(C)(C)c1ccc(Br)cc1 +O=C(c1ccc2c(c1)nc1n2CCOC1)N1CCCCC1 +O=C(Cn1ccc2ccccc21)NCCNC(=O)c1ccc(O)cc1 +O=C(CC1CC1)N1CCC2OCCCC2(COc2ncccc2F)C1 +CC(C)CCNC(=O)N1CCN(CC(=O)NC2CC2)CC1 +CCCn1c(N)c(Sc2ccccc2)c(=O)n(CCC)c1=O +COCCNC(=O)c1csc(Nc2ncccn2)n1 +OC1(c2cccc(C(F)(F)F)c2)CCN(Cc2cnc[nH]2)CC1 +O=C(NCC(F)(F)F)C1CCN(C(=O)c2ccccn2)CC1 +CCC(NS(=O)(=O)c1ccc(Br)cc1)C(N)=O +CN1CCCC2(CCN(C(=O)CCCn3cnnn3)C2)C1=O +c1ccc(CCCNc2ccc(-c3nc(C4CC4)no3)cn2)nc1 +CC(=O)Nc1c(C(=O)Nc2ccc(F)c(F)c2)oc2ccccc12 +CCOc1ccc(NC(=O)c2cc(S(C)(=O)=O)ccc2C)cc1 +C=CCc1cccc(Cl)c1OCCN1CCOCC1 +CC(C)CN(CC(C)C)C(=O)c1ccc2c(c1)OCO2 +COc1ccc(-c2c(C)sc(NC(=O)c3ccncc3)c2C#N)cc1 +CC(CC#N)N(C)C(=O)Nc1ccccc1N(C)Cc1ccccc1 +CCOC(=O)N1CCN(C(=O)c2nn3ccccc3c2Cl)CC1 +CC(=O)C(C)n1nc(C#N)cc1-c1ccc(F)cc1 +CN1CCN(S(=O)(=O)c2cccc(F)c2)c2cnccc21 +Cc1ccc(C(=O)N2CCN(C(=O)NC(C)CCCO)CC2)s1 +Cc1ccnc(N2CCC(C(=O)NC(C)Cc3ccco3)CC2)n1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)N1CCOC(C)C1 +CCNC(=O)C(C)NC(=O)NCc1ccc(F)cc1 +Cc1ccc(C(=O)N2CC=C(c3ccccc3)CC2)o1 +CC(CC(O)=Nc1ccc(F)c(F)c1)n1ccnc1 +Cc1cc(C)nc(-n2nc(C)c3c2NC(=O)CC3c2ccsc2)n1 +CCN(CCO)C(=O)C(C)Oc1cccc(Cl)c1Cl +Cc1nc2c(s1)C(NC(=O)NC1c3ccccc3CC1O)CCC2 +COc1ccc(C(=O)CCCC(=O)Nc2ccncc2)cc1 +Cc1cc(Cl)cc2c(=O)n(CC(C)(C)CO)cnc12 +O=C(NCc1ccc(Cn2cnc3ccccc32)cc1)N1CCC1 +CCOCCOC(C)C(=O)Nc1ccc(C)c2cn[nH]c12 +Cc1ccc(-n2nc(-c3ccc(F)cc3)c(C#N)c2N)cc1 +O=C(Cn1ncc2ccccc21)c1cccc(F)c1 +NC(=O)c1ccccc1OCC(=O)Nc1ccc(Cl)cc1 +CCOc1ccccc1-c1nc(CC(=O)NCC2CCOC2)cs1 +Cc1cc(C)n(-c2ncnc(Nc3nc(C)c(C)s3)c2N)n1 +CC(C)n1ccc(Cc2nc3cc(F)ccc3c(=O)[nH]2)n1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccc3oc(C)nc3c2)c1C +CC(C(=O)N(C)CC(=O)N=c1[nH]nc2ccccn12)n1cccn1 +COc1cc(C(=O)NCC(=O)N(C)C)ccc1C +CC(CNC(=O)NCCC1CCCC1)Cn1cccn1 +Cn1nccc1CNC(=O)C1CCCN1C(=O)c1ccco1 +Cc1noc(C)c1CCC(=O)NCc1ccccn1 +CCN(CCCNc1nc2ccccn2c1C#N)S(C)(=O)=O +CCCc1nnc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)s1 +Cc1nnc(COC(=O)c2cc3c(s2)CCCCC3)o1 +CN(C(=O)OC(C)(C)C)C1CCN(CC(=O)c2nccs2)CC1 +O=C(Cc1ccon1)NCCC(=O)NC1CCCCC1 +O=C(Nc1ccc(F)c(F)c1F)c1cncn1-c1ccccc1 +N#CC1C(=O)Nc2nn(-c3ccccc3)c(O)c2C1c1cccnc1 +CCC1CCCCN1C(=O)NCCCOCC(F)(F)F +O=C(NC1C=CC(CO)C1)NC1CCCCc2ccccc21 +O=C(CSc1ncnc2nc[nH]c12)NCc1ccco1 +CC1CCC(C(C)C)N(C(=O)c2cnc(C3CCCO3)s2)CC1 +Cn1ccnc1C(NC(=O)Cn1cnc(C#N)n1)c1ccccc1 +CCOC(=O)c1sc(-c2cccc(N)c2)nc1C(F)(F)F +CCCN(Cc1cnc2ccsc2c1)CC(F)F +Cc1ccc(C)n1-n1cnc2scc(-c3cccs3)c2c1=O +CC(=O)Nc1nc(CN2CCCc3ccccc32)cs1 +Nc1nccnc1C(=O)NCC(=O)Nc1ccc(F)c(F)c1 +Cc1cc(F)cc2c1CCNC2c1ccc2c(c1)OCCO2 +NC(=O)NC(CC(=O)NCc1ccccc1Cl)c1cccs1 +COc1ccc(NC(=O)CN2CCCCCC2=O)c(C(F)(F)F)c1 +CCCN(CCC)S(=O)(=O)c1ccc2c(c1)CCCC(=O)N2 +O=C(CCn1c(=O)oc2ccccc21)Nc1ccc(F)c(F)c1 +O=C(NCC(O)c1ccc(F)cc1)C1CC1c1ccc(F)cc1 +CC1CCN(S(=O)(=O)N2CCOC(C(N)=O)C2)C1 +COCc1ccc(C(=O)N(C)C2CCN(c3ccccc3)C2=O)cc1 +O=C(NCCn1nc(C(F)(F)F)c2c1CCCC2)c1ccco1 +CC1CCN(C(=O)CCCC(=O)c2cc(F)ccc2F)CC1 +Cc1nccc(-c2nnc3nc(-c4ccco4)nn3c2C)n1 +Cc1cc(C)c(CNC(=O)c2cc(CC(C)C)n[nH]2)c(=O)[nH]1 +CCc1c(C)sc(NC(=O)c2cccs2)c1C(N)=O +CCNC(=O)NC1CCC(OC(=O)c2ccccc2COC)CC1 +COc1ccc(NC(=O)NCC(C)(C)c2ccncc2)c(C)n1 +CCOc1ccccc1NC(=O)c1ccc(OCC#N)c(OC)c1 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccc(OC(F)F)cc1 +Nc1cc2c(cc1Oc1cccc(Cl)c1)OCCO2 +CCN(CC(C)C#N)C(=O)CN1CCN(C(=O)OC)CC1 +N#Cc1ccc(C(=O)Nc2ccc(Cl)c(N)c2)cc1 +CC(C)N(C)C(=O)CCCNC(=O)c1cccs1 +O=C(NCCCN1CCOCC1)C1CCCCC1 +CCc1ncc2c(n1)CN(c1ncccc1C(F)(F)F)C2 +Cc1cnn(CC2CCCCN2C(=O)C2CC2c2cccnc2)c1 +CN(CCNC(=O)C1(c2cccs2)CC1(C)C)S(C)(=O)=O +CC1(NC(=O)Cc2ccc(S(N)(=O)=O)s2)CCCC1 +O=C(Nc1cccc(Cl)c1)c1cc2ccccn2n1 +Cc1ncc(CNS(=O)(=O)c2cccc(C(N)=O)c2)s1 +CCC(C)C(NC(N)=O)C(=O)Nc1cccc(C)c1 +CN(C(=O)Nc1c(F)cccc1F)C1CCN(c2ccccc2)C1=O +O=C(CCCc1nc2ccccc2c(=O)[nH]1)NC1CC1 +COc1cccc(CC(NC(=O)c2cc[nH]c2C)C2CC2)c1 +Cc1nscc1C(=O)NCCc1ccccc1Cl +Cc1cccc(NC(=O)COC(=O)C2CC=CCC2)c1 +CCn1nc(C(=O)NC2CCCCC2)c(=O)c2ccccc21 +CCc1cc(NC(=O)C2COc3ccc(F)cc3C2)n(C)n1 +CC(Sc1nnc(C2CC2)n1CC(N)=O)c1ccc(Cl)cc1 +CS(=O)(=O)c1cccc(NCc2noc(-c3cccs3)n2)c1 +O=C1c2cccc3cccc(c23)N1Cc1ccccn1 +COc1ccc(C(=O)N(C)Cc2cccc(F)c2)c(F)c1 +Cc1ccc(NC(=O)C2CC3C=CC2C3)cc1S(=O)(=O)NC1CC1 +Nc1ccccc1-c1nnn(CC(=O)NC2CCCCC2)n1 +CS(=O)(=O)N1CC(c2nc[nH]n2)c2cc(C(=O)NC3CC3)ccc21 +Cc1cccc(NC(=O)CSc2nnc(C)n2C2CC2)c1 +CCN(CC(C)C#N)C(=O)c1c[nH]nc1-c1ccccc1Cl +COC(=O)c1cc2ccc(Br)cc2[nH]1 +Cc1csc(SCc2nnc(C3CC3)o2)n1 +Cc1cc(C)c(NC(=O)c2cc(C)n(-c3ccccc3)n2)c(C)c1 +COc1ccc(NC(=O)CCCn2c(=O)oc3ccccc32)cc1 +COC(=O)C(C)(C)NC(=O)Cn1cnc2ccccc2c1=O +O=C(c1cc2n(n1)CCCO2)N(CCO)C1CCCCC1 +CCNC(=O)CNS(=O)(=O)c1c(Cl)cc(Cl)cc1Cl +CCC(C(=O)NC1CC1)N(c1cc(C)ccc1C)S(C)(=O)=O +COC(=O)c1cccc(OCCSc2nccn2C)c1 +Cc1cc2c(cc1S(=O)(=O)N1CCC(C)CC1)OCCN2C +COC(CNC(=O)CCC1CCCC1)c1ccsc1 +O=C(NCCNC(=O)c1nc(C2CCCCC2)no1)c1ccccc1 +O=S(=O)(Nc1cccc2c1OCCO2)c1cccc2cnccc12 +Cc1csc(N(CC(F)(F)F)C(=O)CC(F)(F)F)n1 +Cc1cccc(C2(C(=O)N3CCC(C(N)=O)C3)CCCC2)c1 +CC1CN(C(=O)Nc2nn(C(C)(C)C)cc2C#N)CCO1 +Cc1cc(-c2nnc(CCC(=O)NC3CCc4ccccc43)o2)no1 +Cn1c(=O)oc2cc(C(O)C3CCCOC3)ccc21 +COc1ccccc1C(NC(=O)Cn1ccnc1)C(C)(C)C +O=C(c1csc(-c2nc[nH]n2)n1)N1CCCC1CC1CCCCC1 +COc1cccc(C(=O)NCc2cc(=O)oc3c(C)c(C)ccc23)c1 +COC(=O)c1[nH]c(C)cc1NS(=O)(=O)c1ccc(F)cc1 +O=C(Cn1cc(Br)ccc1=O)Nc1cccc(F)c1 +N#Cc1c(-c2ccc3c(c2)OCCO3)c2c([nH]c1=O)CCCC2 +CCC(CC)C(=O)N1CCC(NC(=O)Nc2ccnn2C(C)C)CC1 +CCOC(=O)N1CCN(c2nc(CC)nc3sc(CC)cc23)CC1 +COc1ccccc1NCc1ccc(OC)c(OC)c1 +COc1ccc2nnc(C(=O)NCc3cccs3)nc2c1 +CSc1ccc(C(=O)OCC2(C)COC2)cn1 +Cn1cccc1C(=O)N1CCOC2CC(COc3ccccn3)CC21 +CC(COc1ccc(F)cc1F)NC(=O)Cn1ccc(=O)[nH]c1=O +Cc1ccccc1C(C)NC(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +COCc1ccccc1NCc1cnn(-c2ccccc2)c1 +CCCc1nc(CNc2ccccc2C(N)=O)cs1 +Cc1ccc(S(=O)(=O)Oc2ccc(-n3ccnc3)cc2)cc1C +CCNC(=O)C(NC(=O)c1ccc(C)cc1)C(C)C +Cc1noc(C)c1CC(=O)NC1CCN(C(=O)c2ccoc2)CC1 +O=C1Nc2ccc(Cl)cc2C1Nc1cc(F)cc(F)c1 +CCC(C#N)OC(=O)c1cccc(OCC(F)F)n1 +COC(=O)c1sccc1NC(=O)Cc1ccccc1OC +CC(C)N(C)S(=O)(=O)c1ccc(C(=O)OCc2ccccn2)cc1 +COCC1CCN(C(=O)Cc2c(F)cccc2F)CC1 +O=C(COCc1cc(-c2ccco2)on1)N1CCCC1 +COc1cccc(C(O)CCCC(=O)N2CCCCCC2)c1 +OC(CNc1ccccc1Br)c1cccs1 +CC(C)CNC(=O)c1cc(-c2ccccn2)nc2ccccc12 +O=C(NC1c2ccccc2CC1O)c1cccc2c1OCCO2 +CC(CCc1ccco1)NC(=O)Nc1cn(C)c(=O)c2ccccc12 +COc1ccc(CNS(=O)(=O)c2ccc(-n3cccn3)cc2)cc1 +CCn1ccc(C(=O)N=c2sc3cccc(OC)c3n2C)n1 +Cc1cc2cc(CNc3ccc(F)cc3)c(=O)[nH]c2cc1C +CCOC(=O)C1=C(CNc2cc(F)ccc2C)NC(=O)NC1 +CNC(=O)COc1cccc(OCc2ccccn2)c1 +CN(C)C(=O)N1CCN(CCOc2ccccc2)CC1 +O=C(Nc1ccccc1C(=O)N1CCCCC1)c1cccs1 +C=CCN1CC(C(=O)Nc2ccc(NC(=O)CC)c(Cl)c2)CC1=O +CCc1noc(CCn2cnc3scc(C)c3c2=O)n1 +Cc1cccc(-n2nnc(C(=O)NCc3ccccc3Cl)c2N)c1 +CC(C)Cc1cc(C(=O)N2CCCC2c2ccco2)n(C)n1 +N#Cc1ccccc1N1CCCN(c2cncc3nnnn23)CC1 +Cc1cc(C)c(S(=O)(=O)NCCn2cnc3ccccc32)c(C)c1 +O=C(COC1CCCC1)Nc1ccc(-n2cccn2)nc1 +O=C(NCc1ccccn1)c1cc(=O)c(OCc2ccccc2)c[nH]1 +COc1ccc(-c2cc(=O)n(CC(=O)NCC3CCCO3)cn2)cc1 +O=C(CNC(=O)c1ccccc1)Nc1ccc(F)cc1NC1CC1 +CCCOC(C)C(=O)N1CCc2c(nc[nH]c2=O)C1 +Cc1cc(S(=O)(=O)NCCn2ncccc2=O)c(C)cc1Cl +COc1ccc(NC(=O)N2CCN(CC(=O)NC3CC3)CC2)cc1C +CC(=O)Nc1ncc(S(=O)(=O)NC2CCCCC2)s1 +CCNS(=O)(=O)c1ccc(C(=O)N(C)C2CC2)cc1 +Cc1nc2ccccc2n1CCNC(=O)N1CCC(C)CC1 +CC(NS(=O)(=O)Cc1ccon1)c1cccc(-n2cccn2)c1 +CN(CCc1ccncc1)Cc1c(C2CCCC2)[nH]c2ncccc12 +COc1ccc(C(N)C(=O)NCCCO)cc1OC +COC(=O)NCCCC(=O)NC1CC1c1cccc(Cl)c1 +CCc1ccccc1NC(=O)c1cnc2ccccn2c1=O +Cc1cc(Cl)ccc1OC(C)C(=O)NC(C)CO +O=C(Oc1ccc2c(=O)c(-c3ccccc3)coc2c1)C1CCCO1 +CNc1nc(-c2ccc3c(c2)OCCCO3)c(C)s1 +Cc1nc(C(=O)Oc2ccc(S(C)(=O)=O)cc2)cs1 +COC(=O)c1c(SC)nn(-c2ccccc2)c1N +CCCNC(=O)c1cc(C)c(C)c(S(N)(=O)=O)c1 +COc1cc(C)ccc1NC(=O)CNC(=O)CC(C)(C)C +COCC(=O)N1CC(OCc2cccc(C)n2)C2OCCCC21 +COc1cc(OC)cc(-c2nc3c(C)ccnc3o2)c1 +Cc1nc(C#N)c(C#N)n1Cc1cccc(C(=O)N(C)C)c1 +c1cc(-c2nccn2Cc2ccc3c(c2)CCCO3)ccn1 +CCCC1CN(C(=O)CNC(=O)c2ccccc2OCC)CCO1 +CC(Sc1nncn1C)C(=O)NCC(F)(F)F +CC(C)c1ncncc1C(=O)N1CCOC(c2ccc(Cl)cc2)C1 +O=c1cc(NCC(O)c2cccc(F)c2)nc2ccccn12 +CCSc1nc2c(c(-c3cccs3)c1C#N)CN(C)CC2 +CN(Cc1ccc(F)cc1)C(=O)CNc1cc(F)ccc1F +COc1ccc(OC)c(NC(=O)Nc2ccc(NC(C)=O)cc2)c1 +CC(Oc1ccc(Br)cc1)C(=O)N1CCC(C(N)=O)C1 +CC(CNc1nncc(-c2ccccc2F)n1)Oc1cccnc1 +COC1C2=C(CCCC2)C(=O)N1Cc1ccccc1 +COC(=O)c1cc(Nc2ncnc(N(C)C)c2N)cc(C(=O)OC)c1 +CS(=O)(=O)c1ccc(C(=O)NC2CCC3CCCCC3C2)cc1 +C#CCOc1ccc(CN2CCOC3CCCCC32)cc1 +Cc1ccc(F)cc1S(=O)(=O)NCc1cnn(C)c1 +Cc1cc(C(=O)NCCn2nc(C)cc2C)c2c(C)noc2n1 +Nc1c(Cl)cccc1C(=O)Nc1ccccc1F +O=C(Cn1cnnn1)NCCc1csc(-c2ccccc2)n1 +COCc1cc(=O)[nH]c(Nc2ccc(C)cc2F)n1 +COCCNC(=O)c1cnn(-c2cccc(C)c2)c1C +CN(CCCOc1ccc(Cl)cc1)S(C)(=O)=O +COc1ccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)nn1 +CC1CC(C)CN(C(=O)c2cc3c([nH]c2=O)CCCC3)C1 +CC(C)N(Cc1cccnc1)C(=O)CNC(=O)c1cccc(F)c1 +COCCNC(=O)Cn1nc(-c2ccco2)cc(N)c1=O +CC(C)c1noc(Cn2cnc3ccsc3c2=O)n1 +CC(=O)Nc1ccc(Nc2nc(-c3ccc(O)cc3)cs2)cc1 +Cc1csc(CNS(=O)(=O)c2ccc(C)c(C)c2)n1 +COc1ccc(N(C)C(=O)c2cnn(C)c2)cc1OC +CCN(Cc1ccccc1Cl)C(=O)c1ccco1 +C#CCNC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1 +Cc1nnc2sc(COc3ccc(C(C)(C)C)cc3)nn2c1=O +COc1cnc(C(=O)Nc2ccccc2Cl)cc1O +O=C(CO)N1CCCC(c2nccnc2-c2ccc(F)cc2)C1 +CCC(C)C(NC(=O)c1cc(S(C)(=O)=O)ccc1C)C(N)=O +O=C(OCCNc1cccnn1)C1CCN(c2ncccn2)CC1 +COc1ccc(-c2noc(Cn3cnnn3)n2)cc1OC +COc1cccc(NC(=O)N2CCCC(C(=O)NC3CC3)C2)c1 +O=C(NCc1ccccn1)NCC1(c2ccccc2F)CC1 +Cn1cc(CN2CC3COCC3(C(=O)NCc3cccs3)C2)cn1 +O=C(Nc1cccc(F)c1)C1CCCN1C(=O)C1CC1 +Cc1csc(NC(=O)c2cc3ccccc3n2C)n1 +C=CCn1nnc(NC(=O)COc2ccccc2C)n1 +CC(=O)NC(C(=O)Nc1cc(C(F)(F)F)ccc1Cl)C(C)C +N#CCCSc1nnc(-c2cccnc2)n1Cc1ccccc1 +CCc1cc(C(=O)N2CCC(C(=O)N3CCCC3)CC2)no1 +CS(=O)(=O)N1CCCC1C(=O)N1CC(=O)Nc2ccccc21 +COc1cccc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)c1OC +CCCNC(=O)C(C)NC(=O)NC(C)C(=O)NCC +CC(=O)c1csc(C(=O)NC(C)CC(O)c2ccccc2)c1 +COc1cc(OC)c(CNC(=O)N(C)CC2CC2)c(OC)c1 +CCCC(=O)Nc1cccc(C(=O)NCc2ccccc2OC)c1 +Cc1ccc(C(=O)COC(=O)c2ccncc2)cc1C +O=C(CN1CCc2ccccc2C1)NC1CCCC1 +CC1Cc2ccccc2N1C(=O)NCCc1cccc(O)c1 +CCCCNC(=O)C(C)n1cnc2c1c(=O)n(C)c(=O)n2C +CCc1nonc1NC(=O)COc1ccc(Br)cc1 +COC(C)(C)c1noc(-c2ccc(-n3nc(C)cc3C)c(F)c2)n1 +COc1ccc(OCCCSc2cc(C#N)ccn2)cc1 +O=C(Nc1nc2c(s1)CCCC2)C1(n2cnnn2)CCCCC1 +Cc1ccnc(-c2ccc(NC(=O)NCc3ccccc3F)cc2)n1 +Cc1nnc(SCC(=O)N(C)CC2COc3ccccc3O2)o1 +Cc1cc(F)c(S(=O)(=O)N(C)Cc2scnc2C)cc1F +Cc1cccc(-n2nnc(C#N)c2-c2cccnc2)c1C +CC(=O)N(C)Cc1cccc(NC(=O)NCc2ccncc2)c1 +Cc1cccc(NC(=O)C2CCCN(Cc3cncs3)C2)n1 +CCNC(=O)CN(C)S(=O)(=O)c1ccc(N)cc1C +CNC(=O)CNC(=O)Cc1n[nH]c(=O)c2ccccc12 +CCN1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1 +Cc1nnc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)s1 +CCCC(=O)Nc1nnc(S(=O)(=O)N2CCC(C)CC2)s1 +Cc1noc(C)c1CC(=O)NCc1ccc(OC(C)C)cc1 +COC(=O)CCCC(=O)Nc1ccc(Br)cc1 +O=C(COC(=O)CSc1ccccc1)Nc1ccc(Cl)cn1 +Cc1nnsc1C(=O)NCc1cc(C2CC2)n(C2CCCC2)n1 +Nc1c(-c2ccccc2)nnn1-c1ccccc1Cl +Cc1ccc(C(=O)N2CCn3c(nnc3C(C)C)C2)s1 +C#CCNC(C)(Cc1ccccc1OC)C(=O)OC +Cc1occc1CN(C)C(=O)NC1CCCC(C)C1 +O=C(Cc1ccc2c(c1)OCC2)N1CCN(c2ccccc2)CC1 +O=C(NCc1ccnc(-n2cccn2)c1)C1CC2CCC1C2 +Cc1cc(C2CN(Cc3ccc(C#N)o3)CCO2)ccc1F +O=C(NCCCN1CCCC1=O)c1ccn2ccsc12 +CCCc1noc(COc2ccc3c(C)cc(=O)oc3c2)n1 +CCc1nc(C)c(C(C)N(C)Cc2ccccc2OC)s1 +c1cc(-c2nc(CSc3nnc(C4CCCCC4)o3)no2)co1 +O=C(CNC(=O)OCc1ccccc1)NC1CCCC1 +CC(O)Cc1cn(C2CCN(c3ncccc3C#N)CC2)nn1 +Cc1noc(C)c1CCC(=O)NCC(C)N1CCOCC1 +C#CCOC(=O)c1cc(C2CC2)nc2c1cnn2C(C)C +CC(C)NC(=O)CSc1nnc(-c2ccc(F)cc2)n1C +CC1CCC(=O)N1c1ccc(NC(=O)N2Cc3ccccc3C2)cc1 +C#CCC(OC(=O)c1ccccc1F)c1ccccn1 +O=C(NC1CCCNC1=O)c1ccc(S(=O)(=O)C(F)F)cc1 +Cc1ccnc(NC(=O)c2oc3c(c2C)C(=O)CC(C)(C)C3)c1 +CC(Sc1nc(-c2ccccc2)ns1)C(=O)NCC1CCCO1 +Cn1c(CNC(=O)c2cc(Cl)c[nH]2)nc2ccccc21 +O=C(c1cnccn1)N1CCN(CCOc2ccc(Cl)cc2)CC1 +CC1CCCCC1Nc1nnc(S(=O)(=O)CC(C)(C)O)s1 +Cc1ccc(NC(=O)c2ccc3c(c2)OCCCO3)cc1 +CN(C(=O)CSc1ccc(O)cc1)C1=CCCC1 +CC(C(=O)NC1CCSc2ccccc21)n1cncn1 +CCCC(C)NC(=O)C1CCCN(C(=O)c2ccc(C)s2)C1 +COc1ccc(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)cc1 +O=C(Nc1nnc(C2CC2)s1)c1cccc(CN2CCCC2=O)c1 +O=C(Nc1ccc2c(c1)OCCO2)Nc1ccccc1Br +COc1cc(-c2noc(-c3ccc(=O)n(-c4ccccc4)n3)n2)ccn1 +Cc1ccc(SCCC(=O)NCC(N)=O)cc1C +Cn1c(N)c(C(=O)c2ccccc2)c(=O)n(C)c1=O +COCc1ccccc1C(=O)Nc1ccc(-c2ccccc2)nn1 +Cc1ccc(S(=O)(=O)N(C)CCc2ccccn2)cc1 +O=C(CNc1ccc(F)c(F)c1F)N1CCCC1 +O=C(NC1CCCCCC1)c1csc(Nc2ncccn2)n1 +COCCn1cc(NC(=O)N2CCCC(NS(C)(=O)=O)C2)cn1 +Cc1ccc(CNC(=O)C2CCN(S(N)(=O)=O)CC2)cc1F +CCn1c(C)nc2cc(C(=O)CN3CCC(=O)CC3)ccc21 +Cc1ccc(S(=O)(=O)N(C)CCOc2ccccc2)cc1 +O=C(Nc1nc(-c2cccnc2)cs1)c1cccc(Cl)c1 +NC(=O)Cc1cccc(OS(=O)(=O)c2ccc(Cl)cc2F)c1 +NC(=O)c1ccnc(N2CCCC(c3nc4ccccc4[nH]3)C2)c1 +COc1ccc(C)cc1NC(=O)C(N)c1ccccc1 +CCOC(=O)c1c(NC(=O)OC)sc2c1CCCC2=O +COC(=O)C(CO)NC(=O)Nc1cccc(F)c1 +CC(C)NC(=O)Nc1ccn(Cc2ccccc2)n1 +CCc1ccccc1OCC(=O)Nc1c(C)noc1C +CC(C)c1ncc(Cl)c(C(=O)N2CCN(C(C)C)CC2)n1 +CCC(C)NC(=O)c1ccc(NC(=O)NCc2ccccc2)cc1 +CC(C)(C)c1nc2cc(NC(=O)c3cc(C4CC4)on3)ccc2[nH]1 +CNC(=O)c1ccc(CSc2ccccc2)cc1 +Cc1nccc(-c2cccc(NC(=O)c3cc(-c4ccco4)on3)c2)n1 +Cc1cc(F)ccc1NC(=O)CNC(=O)c1cccc(F)c1 +Cc1ccc(-n2nnnc2N2CC3CCC2C3)cc1 +CC(C)C(=O)N1CCCC2(COCCN(c3ncccn3)C2)C1 +O=C(c1ccsc1)N1CCOC(Cc2ccccc2Cl)C1 +CCn1c(-c2ccccc2)nnc1S(=O)(=O)Cc1ccc(F)cc1 +Cc1ccoc1C(=O)NC1CCN(C(=O)Nc2ccccn2)CC1 +CCOC(=O)N1CCC(OC(=O)C2CC2c2ccc(F)cc2)CC1 +CCC(=O)N1CCC(NC(=O)c2ccncc2)CC1 +Cc1cccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)c1C +Cc1sc2ccccc2c1S(=O)(=O)N=c1cccc[nH]1 +CCNc1nc(-c2sc(N(C)C)nc2CC)cs1 +Cc1cc(=O)oc2cc(OCC(=O)c3cnn(C)c3)ccc12 +CCC(C)(C#N)NC(=O)c1cc(OC)c(OC)cc1C +CCOc1ccc(F)c(C(=O)NC(C)(C)C(=O)N(C)C)c1F +CN(CCc1c(F)cccc1Cl)C(=O)CCCO +Cc1nc(NC(=O)N(Cc2ccncc2)C2CC2)oc1C +CC(NC(=O)C(C)N1CCN(CC(F)F)CC1)c1ccc(F)cc1 +O=C(Nc1ccc2c(c1)OCO2)C1CCN(C(=O)NC2CC2)CC1 +Cc1cccc(Nc2ncnc(Nc3cccc4ncccc34)c2N)n1 +CC(C)c1nc2c(N)cccc2n1CC(=O)N1CCCCC1 +COc1cc(NC(=O)N(C)CCc2ccc(F)cc2)ncn1 +NC(=O)Cc1csc(NC(=O)C2Cc3ccccc3S2)n1 +CC(=O)Nc1ccc(OC(=O)C2(c3ccc(Cl)cc3)CC2)cc1 +CCOC(=O)CSc1cc(C(F)(F)F)nc(-c2cccnc2)n1 +CN(Cc1n[nH]c2c1CCCC2)c1cc(N2CCOCC2)nc(N)n1 +N#Cc1cccnc1Nc1ccc2nc(N3CCOCC3)sc2c1 +CSc1nsc(NC(=O)Cc2c(C)nn(C(F)F)c2C)n1 +COCCNC(=O)c1cc(-n2cccc2)ccc1Br +CCCS(=O)(=O)N1CCOC2C(OCc3ccccn3)CCC21 +O=c1cc(CNc2cc(F)ccc2Cl)nc2ccccn12 +COC1CCCC1OC(=O)Cc1csc(N2CCCC2=O)n1 +CCNC(=O)CN(CC)S(=O)(=O)c1ccc(C)cc1C +CCCCOc1cccc(-c2cc(C(=O)NCC)nc(N)n2)c1 +O=C(c1ccc(-c2ccsc2)s1)N1CCc2c(nc[nH]c2=O)C1 +CC(C)C(=O)N1CCC(C(=O)OC(C)c2ccccc2)CC1 +CCc1nn(C)c(OC)c1CNc1cc(C)on1 +Cc1ccc(O)c(SCC(=O)c2ccccc2)n1 +CCn1cc(C(=O)N(Cc2ccc3c(c2)OCO3)c2ccccc2)cn1 +CN(C)C(=O)C1CC2CN(Cc3cnn(C)c3)CC1O2 +CCCNC(=O)c1cccc(NC(=O)CSc2nncn2C)c1 +CC(=O)N1CCN(CC(O)c2ccc(OC(C)C)cc2)CC1 +Cc1cc(CC(C)NC(=O)N2CCc3cc(F)ccc3C2)n[nH]1 +CC(C)(C)OC(=O)N1CCC(Nc2cn[nH]c(=O)c2Cl)C1 +CCOc1ccc(NC(=O)CNc2ccccc2OC)cc1 +CC(C)Oc1cccc(N(CC(N)=O)S(C)(=O)=O)c1 +Cn1c(-c2ccc(Cl)cc2)cn2c3ccc(N)cc3nc12 +CC(NC(=O)Nc1cnn(C)c1)C(=O)NCc1ccccc1 +COc1cccc(C2CCCN2C(=O)C2CC=CCC2)c1 +CC(C(=O)N1CCCc2cc(S(C)(=O)=O)ccc21)c1ccsc1 +COc1ccc(C)cc1CCNC(=O)c1cc(C)sc1C +CC(C)n1ncc2c(=O)[nH]c(C=Cc3ccn(-c4ccccc4)n3)nc21 +c1ccc(-n2ccnc2)c(Cn2ccnc2-c2ccc3c(c2)OCO3)c1 +Cc1cc(C)c(C(=O)Nc2ccccc2C(N)=O)c(C)c1 +Cn1cc(C(=O)NCCc2c[nH]c3ccccc23)c2ccccc2c1=O +COCCNC(=O)c1cnn(-c2cccc(F)c2)c1-n1cccc1 +N#Cc1ccc(NCCNC(=O)CC2CCCCC2)nc1 +Cc1ccc(-n2nc(C)c(CC(=O)NCC(C)O)c2C)cc1Cl +O=c1[nH]c2ccccc2c(=O)n1Cc1cccc(F)c1 +Cc1ccncc1NC(=O)N1CCC(S(=O)(=O)NC2CC2)C1 +Cc1nc(N(C)C)sc1CN1CCN(Cc2ccncc2)CC1 +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cnc2ccccn2c1=O +CC(=O)N1CCN(C(=O)CCOCC2CCCO2)CC1 +CC(C)CCC(=O)OCc1nc(-c2ccccc2)no1 +CCOC(=O)C1CCCN(C(=O)c2cc(Cl)ccc2Cl)C1 +C=CCN1C(=O)c2ccccc2NC12C(=O)Nc1ccc(F)cc12 +CC(=O)N1CCCC1C(=O)NC(C)c1cc(C)oc1C +O=C(NCC1Cc2cccc(-c3ncccn3)c2O1)c1ccco1 +O=C(Nc1cc2ccccc2oc1=O)c1ccc(-n2cncn2)nn1 +CN(C)C(=O)Sc1ccccc1NC(=O)c1ccc2[nH]ccc2c1 +COc1cc(C(=O)N2CCCC2)cc(OC)c1Br +COCCOc1ccc(-c2ncc(F)c(N(C)C)n2)cc1 +CCCC1CN(C(=O)CCc2c[nH]c3ccccc23)CCO1 +N#CC1C(=O)N=C(c2ccccc2)C=C1c1ccccc1 +Cc1cc(C)c(NCC(=O)Nc2c(C)cccc2C)c(C)c1 +COc1cc2c(cc1O)CCNC2c1cc2ccccc2[nH]1 +CN(CCCC(N)=O)S(=O)(=O)c1ccc(Cl)cc1 +O=C(Cc1ccc2c(c1)OCCO2)Nc1cccc2ncccc12 +COCCNC(=O)CNC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +Cc1ccc(CNC(=O)Nc2cnn(C)c2)c(OCC2CCOC2)c1 +COc1ccc(F)cc1NC(=O)NCC1(C(=O)N(C)C)CCCC1 +CCc1nnsc1C(=O)NCc1ccc(C(F)(F)F)cc1 +Cc1nc(CC(=O)c2c(C)cc(O)cc2O)cs1 +CCc1c(C)nc(-n2nc(C)cc2C)n(CC(=O)N2CCCC2)c1=O +CC1CN(CC(=O)N2CCc3ccccc32)CC(C)O1 +Cc1ccc(C(O)CNc2c(C)cccc2C)cc1C +Cc1cc(C)c(-n2nnnc2SCC(=O)N2CCCCC2)c(C)c1 +COc1ccccc1C=CCN1CCOC(C)C1C +NC(=O)c1cnn(CC(O)COc2ccccc2)c1 +CCNC(=O)c1cccc(-n2c(C)nc3cccnc32)c1C +Cc1ccn2c(=NC(=O)c3cc(C#N)cn3C)[nH]nc2c1 +Cc1cc(C(C)NC(=O)Nc2ccc(Cl)cc2)c(C)o1 +CCCNC(=O)Cn1c(-c2ccc(C)cc2)ccc(C#N)c1=O +CC(=O)Nc1ccc(C#CCNC(=O)c2cccs2)cc1 +Cc1noc(C2CCCN2C(=O)Nc2ccc(C(C)(C)C)cc2)n1 +CC(O)CN1CCN(C(=O)c2ccccc2-c2ccccc2)CC1 +Cc1cc(C)c(C(=O)Nc2cnn(-c3ncccn3)c2)c(C)c1 +COCC(C)NC(=O)Nc1cc(Br)ccc1C +C=CCOc1ccc(CN2CCOC(c3cnn(C)c3)C2)cc1OC +COc1ccc(OCCCn2nnc3ccccc32)cc1 +CC(C)(C)OC(=O)NCC(O)Cc1ccccc1 +CCn1nccc1NC(=O)COc1ccc(OC)cc1 +CC1CCCCC1N(C)S(=O)(=O)N1CCCCCC1 +COCCN(Cc1cccs1)C(=O)c1cccc(-n2cnnc2)c1 +CC(=O)c1ccccc1NC(=O)Cc1csc(-c2ccc(C)o2)n1 +COCC1CCCC12CN(Cc1cccs1)CCO2 +CCC1=C(C(=O)OC)C(c2cccc(Br)c2)NC(=O)N1 +COc1cc(CC(O)CC#N)cc(OC)c1OC +Cc1cccc(N2CCN(CCNC(=O)C(C)NC(N)=O)CC2)c1C +CCNC(=O)C1CCCN(C(C(=O)OC)c2ccc(F)cc2)C1 +Cc1ccc(-c2cc(NC(=O)c3cnc4c(c3)nnn4C)[nH]n2)s1 +CCc1nnc(NC(=O)NCc2cn[nH]n2)s1 +NC(=O)NCCc1ccc(C(=O)OCC(F)(F)F)cc1 +CN(C(=O)C1CC1c1ccccc1)c1nc2ccccc2o1 +Cc1ccc(C(=O)NCCNC(=O)N2CCOCC2C2CC2)cc1 +CCc1cccc(C)c1NC(=O)CCNC(=O)c1ccc(F)cc1F +O=C(NC1CCN(CC(F)(F)F)C1)c1c[nH]c2cccc(F)c12 +Cc1ccccc1OCCCSc1nncn1C +CCC(NC(=O)c1cn(C)nc1C)c1nc(C(F)(F)F)cs1 +Cc1ccc(CC(=O)NC2CCN(C(=O)CC(C)C)CC2)cc1 +CC(=O)c1cccc(NC(=O)c2c(C)cc(C)[nH]c2=O)c1 +Cc1nc(Cn2cc(CCCO)c(C(F)(F)F)n2)cs1 +Cc1ccc(C(C)NC(=O)c2ccc(NC(=O)C3CC3)cc2)o1 +C#Cc1cccc(NC(=O)c2cnc3ccccn3c2=O)c1 +Cc1ccc(F)c2c1CCCN2C(=O)c1ccncc1F +O=C(NCCc1cscn1)C1CCN(C(=O)c2ccccc2)CC1 +CCC(C)Nc1nnc(-c2cccn(CC(C)C)c2=O)s1 +CC(NC(=O)NCc1cccnc1)c1ccc(NC(N)=O)cc1 +COC(=O)CN1CCN(c2nccc3oc(C)cc23)CC1 +COc1ccc(-c2noc(-c3ccc(N4CCCCC4)nn3)n2)cc1 +CC(C)(C)NS(=O)(=O)c1ccc(C(=O)NC2CCCC2)cc1 +CN(CCOc1ccccc1F)Cc1nc2c(cnn2C)c(=O)[nH]1 +C#CCN(CC(C)C)c1c(N)n(CCCC)c(=O)[nH]c1=O +NC(=O)Cc1ccc(Oc2ncc(Br)cn2)cc1 +CC(NC(=O)NCCc1ccc(F)cc1F)C(=O)N1CCCCC1 +CC(C)C1Oc2cc(N)ccc2N(Cc2ccccc2F)C1=O +CC1CC1C(=O)Nc1ccc(-n2cccn2)c(F)c1 +O=C(NCCc1ccc(F)cc1)Nc1ccc(N2CCCC2=O)cc1 +OCc1c(-c2ccc3c(c2)CCC3)nc2sc(C3CCC3)nn12 +Cc1cc(S(=O)(=O)NCCO)c(Cl)cc1Cl +Cc1cc(C)c(C)c(C(=O)NC(C)c2cnn(C)c2)c1C +COC(=O)c1cc2c(ccn2C)n1CC(=O)OCc1ccccc1 +O=C(CCNC(=O)c1ccsc1)Nc1cccnc1-n1cccn1 +CCc1nnc(CNC(=O)Nc2cc3c(cc2OC)OCO3)s1 +CCOc1ccc(-n2ncc(C(=O)NC3CCCCCC3)c2C)nn1 +Cc1ccc(-c2snnc2C(=O)NCc2ccco2)cc1 +CC(C)c1nn(-c2c(F)cccc2F)c2c1CNCC2 +CCNC(=O)C1CCCN(S(=O)(=O)c2ccc(Cl)cc2C)C1 +CS(=O)(=O)NCc1ccc(-c2nc(Cc3ccccc3)no2)o1 +CCSc1nc2ncc3c(=O)n(N(C)C)c(C)cc3n2n1 +O=C1CCC2(CCCN(c3ncccn3)CC2)N1Cc1ccccc1 +CN(C(=O)c1ccc(-c2ccccc2Cl)o1)C1COCC1O +COc1ccccc1Nc1ncnc(N(C)C)c1N +Nc1noc(CCNC(=O)c2ccc(Oc3ccccc3)o2)n1 +Cc1ccc(N2CC(NC(=O)Cc3ccc(F)cc3)CC2=O)cc1C +COCCOCC(=O)Nc1nc(-c2cc(C)sc2C)cs1 +COCCOc1ccc(NC(=O)C2CCC2)cn1 +CCOc1ncccc1-c1ncnc2scc(C)c12 +CC(C)(C)OC(=O)N1CCC(CNc2ncc(F)cn2)C1 +COc1ccc(CCCCC(=O)N2CCNC(=O)C2)cc1 +O=c1[nH]cc(Cl)cc1C1NCCc2c(O)ccc(F)c21 +Cc1ccc(OCC(=O)Nc2nc(C)c(C)s2)cc1 +CCc1noc(CC)c1CC(=O)Oc1ccc(C#N)cc1OC +O=C(NCc1ccc(-c2cccnc2)cc1)NC1(CCO)CCC1 +COCc1c(C(=O)Nc2ccc(N(C)C)nc2)oc2ccccc12 +O=C(NCc1ccco1)C1CCN(c2ncnc3ccsc23)CC1 +CC(NC(=O)COC1CCCCC1)c1ccc2c(c1)CC(=O)N2 +CC(C)Cn1nc(C(=O)N2CCCC2(C)C)c2ccccc2c1=O +Cc1cnc(C(=O)N2CCN(C(=O)c3cccc(Cl)c3)CC2)cn1 +O=S(=O)(Nc1ccccn1)N1CCCCCC1 +O=C(c1cnccn1)N1CCN(c2ccc(-n3ccnc3)nn2)CC1 +NS(=O)(=O)c1cccc(NC(=O)CC2OC(=O)c3ccccc32)c1 +CCc1noc(C)c1C(=O)NCCn1c(C)nc2ccccc21 +O=C(NCCc1cccc(F)c1)c1cc(F)cc2[nH]cnc12 +COc1ccc(C(C)=O)cc1CSc1ncnc2ccsc12 +Cc1ccc(C(=O)Cn2nnc3sc4c(c3c2=O)CCCC4)cc1 +CCn1nc(C(=O)NC(C)c2ccccc2)c(=O)c2ccccc21 +COc1ccc(CO)cc1OCCc1cccc(Cl)c1 +CC(C)(C)C(=O)Nc1cccc(C(=O)NCC(N)=O)c1 +COC(=O)c1c(C)[nH]c(C(=O)N2CCC(c3ccccc3)C2)c1C +CCOC(=O)CSc1nnnn1-c1ccc(C)c(C)c1 +CN(Cc1ccco1)C(=O)CSc1nccn1C1CC1 +Cc1noc(COC(=O)c2ccc(-n3cncn3)c(F)c2)n1 +COc1ccc(S(=O)(=O)NCCc2ccccc2C)cc1 +COc1ccc(Br)c(C(=O)NCCCOC(C)C)c1 +Cc1ccc(N)cc1NC(=O)c1ccc(Br)cc1F +O=C(c1ccoc1)N1CCN(c2nnc3ccc(Cl)cn23)CC1 +O=C(c1noc2c1CCCC2)N1CCC(c2ccccc2F)C1 +CCCc1nc(SCC)c2c(=O)n(C)c(=O)n(C)c2n1 +CN(C(=O)c1cn(Cc2ccccc2)nn1)c1ccc2ccccc2n1 +CC(C)(O)CSc1nnc(Cc2cccs2)n1C1CC1 +N#Cc1cc(NC(=O)c2ccc(F)cc2)c(=O)n2ccccc12 +CNC(=O)COc1ccc(NC(=O)NCc2cnn(C)c2C)cc1 +COCCN(Cc1ccc(C)cc1)C(=O)c1ccccc1C(C)=O +CCOC1CCCN(C(=O)c2ccc(=O)[nH]c2)C1 +C=CCOc1ccccc1CNC(=O)c1ccc(-n2ccnn2)cc1 +CCCCN(C)C(=O)Cn1ncc2c([nH]c3ccccc32)c1=O +CCOC(=O)c1cc2ccc(Br)cn2n1 +C#Cc1cccc(-n2nnc(-c3ccccc3)c2C)c1 +O=C(NCc1cc2ccccc2o1)N1CCCC(CO)C1 +COc1cccc(C(=O)Cc2ccc(C#N)cc2)c1 +CC(C)COCCCNC(=O)Nc1ccc2c(c1)CCC(=O)N2 +CC(C)NC(=O)CN1CC(C)OCC1c1ccccc1 +CCc1cccc(NC(=O)CSc2nc3cccnc3[nH]2)c1 +COc1cccc(-c2noc(NCCc3ccsc3)n2)c1 +Cc1nsc(N2CCN(C(=O)CNCC(F)(F)F)CC2)n1 +CCOC(=O)Nc1ccc(C(=O)c2ccncc2)cc1 +Cc1csc2nc(CSc3nc4ccccc4o3)cc(=O)n12 +Cc1nc(N(C)C)nc(C)c1NC(=O)COc1ccc(Cl)cc1 +NC(=O)COC(=O)c1ccc(Br)cc1F +CSc1ccccc1C(=O)N(C)Cc1noc(C(C)C)n1 +CC(C)c1ccc(C(=O)NCC2CCN(S(C)(=O)=O)CC2)cc1 +C#CCNC(=O)c1ccccc1COc1ccccc1C(=O)NCC#C +CC(=O)c1ccc(N2CCN(C(=O)Cn3cnnn3)CC2)c(F)c1 +NC(=O)c1ccccc1NC(=O)C1CCN(C(=O)c2ccco2)CC1 +CC1CN(S(=O)(=O)c2ccc(N)nc2)CCO1 +CC(NC(=O)c1ccccn1)c1cc2ccccc2o1 +OCc1cccc(OCCCc2ccc3c(c2)OCCO3)c1 +COC(C(=O)Nc1cc(C#N)ccc1Cl)c1ccccc1 +CN(CC(F)(F)F)C(=O)CN1CCOC2CCCC21 +CS(=O)(=O)Nc1ccccc1NC(=O)c1ccc2c(c1)CCO2 +CC(Oc1ccccc1)C(=O)Nc1ccc(-n2ccnc2)nc1 +COC(=O)Nc1ccc(NC(=O)N(C)C(C)c2ccco2)cc1 +COc1cccc(CN(C)C(=O)C2CCN(C(=O)OC(C)(C)C)C2)c1 +CCC(=O)Nc1cccc(C(=O)OCCc2cccnc2)c1 +CCc1nnc2sc(COc3ccc(Br)cc3)nn12 +N#CCCn1c(-c2cccc(N)c2)nc2cc(F)ccc21 +Cc1cccc(Cn2cccc(C(=O)N3CCCC(C)C3)c2=O)c1 +CCOc1cc(C(=O)NCC2Cc3ccccc3O2)ccc1OC +NC(=O)NCC1CCCN(C(=O)NCC2COc3ccccc3O2)C1 +Cc1c(C(=O)OC(C)C)cnc2nc3ccccc3n12 +CC(Cn1cncn1)NC(=O)NCCN1CCOCC1 +CCOc1ccc2nc(NC(=O)Cn3c(C)csc3=O)sc2c1 +O=C(Cn1ccc2c(Br)cccc21)NCc1ccccn1 +O=C(NCCc1c[nH]c(=O)[nH]c1=O)c1cccc(Cn2cccn2)c1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)Oc2ccc(F)c(F)c2)c1 +COc1ccc(CN2CCNC(=O)CC2c2ccccc2)cc1O +COCC(=O)N1CCC2(CC1)NC(=O)CC2c1cnn(C)c1 +O=C(Cc1ccc[nH]1)NC1CCCc2cc(OC(F)F)ccc21 +O=C(c1cccc2nn[nH]c12)N1CCCC1COc1ccccc1 +Cc1cc(C(F)(F)F)nc(CNC(=O)c2ccc3nccnc3c2)n1 +CN(CCOc1cccc(Cl)c1)C(=O)CNS(C)(=O)=O +Cc1cc(C)cc(OC(=O)C(NC(=O)c2ccco2)C(C)C)c1 +CC(CC1CCCC1)C(=O)Nc1ccccc1SCC(N)=O +O=c1oc(CNc2ccccc2)nc2ccccc12 +CC(c1ccccc1F)N(C)C(=O)Nc1ccc2c(c1)OCC(=O)N2 +CCS(=O)(=O)c1cccc(CC(=O)N2CCC3(CCCC3)C2)c1 +CNc1nnc(-c2cc(C)nc3ccc(F)cc23)s1 +Cc1ccc(F)cc1NS(=O)(=O)c1ccccc1F +O=S(=O)(Cc1nc(-c2cccs2)no1)c1ccccc1F +Cc1cccc(OC(C)C(=O)N2CCN(c3ncccn3)CC2)c1 +Cc1nc(CN(C)c2cc(-c3ccccc3)[nH]n2)no1 +OCc1c(-c2ccc(Cl)cc2)nc2sc(C3CC3)nn12 +CNC(=O)c1ccc(Cn2c(-c3ccccc3)noc2=O)cc1 +Cc1cc(O)c2c(c1)C(C(O)c1ccc(O)cc1)NCC2 +Cc1cc(C)c(CNC(=O)c2c[nH]nc2-c2ccncc2)c(=O)[nH]1 +CC(=O)Nc1cccc(CNC(C(N)=O)c2ccccc2)c1 +CCOC(=O)CN(C)C(=O)Cc1ccc(OC)cc1 +Cc1ncsc1C(=O)N1CCC(NS(C)(=O)=O)CC1 +COc1cccc(C2CC(c3cccc(C)c3)n3ncnc3N2)c1 +COCCCNC(=O)c1cnc2sccn2c1=O +CCOC(=O)c1cccc(Br)c1C(=O)OCC +O=C(c1cnc(-c2cccnc2)nc1)N1CCC(CO)C(O)C1 +COC(=O)C1(N(C)C(=O)c2ccc3ccccc3n2)CCCCC1 +O=C(C1CCCC(C(F)(F)F)C1)N1CCCS1(=O)=O +CC1Oc2ccc(CO)cc2N(Cc2ccccc2)C1=O +N#CCCN(CCC#N)C(=O)COc1ccc(C#N)cc1 +CCOc1ccc(C(=O)Nc2cccc(-c3nc(C)no3)c2)cc1 +Cc1ccc(C(=O)N2CCCC(C(=O)NCC(C)CO)C2)cc1 +O=C1NC(O)(c2ccc(Cl)c(Cl)c2)c2ccccc21 +CC(c1nc(C2CC2)no1)N(C)Cc1ccccc1C(F)(F)F +COc1ccnc(NCc2cccc(Cn3nc(C)cc3C)c2)n1 +Cc1cccc(C(C)C)c1NC(=O)NCc1nnc2n1CCC2 +CCOc1ncccc1C(=O)N(C)c1ccc(F)c(F)c1 +CN1CCN(C(=O)c2csc(NC(=O)c3cccc(F)c3)n2)CC1 +CCOC(=O)CC1Nc2cc(C)c(C)cc2NC1=O +Cc1ccccc1CNC(=O)c1cc(S(C)(=O)=O)ccc1Cl +CNS(=O)(=O)c1cccc2c(S(=O)(=O)NC)cccc12 +CN(Cc1nc(N)cc(=O)[nH]1)S(=O)(=O)c1ccc(F)cc1 +Cc1ccc(NC(=O)COc2ccccc2)cc1S(=O)(=O)N(C)C +CN(CCc1cnn(C)c1)c1nc2nonc2nc1N1CCOCC1 +CCC(NC(=O)NC(C)c1c(C)noc1C)c1nc2ccccc2[nH]1 +O=C(CN1CCCS1(=O)=O)Nc1ccccc1Cc1ccccc1 +CCN(C(=O)c1ccc(C)c(NS(C)(=O)=O)c1)C1CCCCC1 +NC(=O)CSc1ccc(C(=O)N2CCCC2)cn1 +O=C(c1cc(Cl)cc(Cl)c1)N1CCC(O)CC1 +O=C(Cc1ccc2c(c1)CCO2)Nc1ccn(Cc2cccnc2)n1 +CC(=O)Nc1ccc(Cl)c(NCC(=O)NCc2ccc(F)cc2)c1 +CCN1CCC2(CCC1=O)CN(c1nc(C)cc(C)n1)CCN2C +Cc1cccc(C(=O)N2CCN(c3nccn3C)CC2)c1 +CC(=O)N1CCCC1C(=O)NCC(C)COCc1ccccc1 +O=C(CSc1ccccc1Cl)Nc1ccccc1-n1cnnn1 +Cn1cnnc1SCCOc1cccc(F)c1 +Cc1cccc(C)c1NC(=O)c1nnn(-c2ccc(F)cc2)c1N +CCOC(=O)c1nc2sc(-c3cccs3)nn2c1C#N +Cc1nnsc1C(=O)Nc1c(C)nc(N2CCCC2)nc1C +Cc1nc(CCNS(=O)(=O)c2ccc(Cl)cc2C)cs1 +Cc1ccc(CNC(=O)Cn2nc(C)c(C)c(C#N)c2=O)cc1F +Cc1cc2c(cc1Br)N(C(=O)c1cnccn1)CC(C)O2 +Cc1nn(Cc2ccc(F)cc2Cl)c(=O)c(C#N)c1C +CCOc1cc(C#N)ccc1OCC(O)c1ccccc1F +CC(NC(=O)CC1CCCCC1)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +CCn1ccnc1N1CCN(C(=O)COc2cccc(OC)c2)CC1 +Oc1cc2c(cc1F)CCNC2c1ccc(F)cc1 +COCCN1CC(C(=O)N2CCCC2c2cccc(OC)c2)CC1=O +O=C(NCCCO)c1ccc(NC(=O)C2CC2)cc1 +O=C(CCOc1ccccc1F)N1CCN(c2ccccc2F)CC1 +Cc1cccc(C(=O)Nc2ccc(N(C)CCO)cn2)n1 +N#Cc1ncn(Cc2cc(F)ccc2Br)n1 +Cc1cc(CN2CCOC(c3ccc(F)cc3)C2)on1 +CC(=O)c1c(C)[nH]c(C(=O)COc2cccc3c2OC(C)(C)C3)c1C +Cn1cnnc1-c1ccccc1NC(=O)CC1CCCCC1 +O=C(NC1CC1)c1ccc(NCc2ccc(F)cc2F)cc1 +CSc1ccc(Cl)cc1NCC(=O)Nc1cc(C)nn1C +Cc1cc(NCc2cc[nH]n2)ccc1NS(C)(=O)=O +COC(=O)C(c1ccc(F)cc1)N(C)Cc1ccco1 +O=C(NCCc1ccc(O)cc1)c1cc(=O)[nH]c(=O)[nH]1 +CC(C)COc1cccc(NS(=O)(=O)c2cn[nH]c2)c1 +Oc1ccc2c(c1)OC(Cc1cccc(F)c1)CN2 +Cc1ccccc1C(=O)N1CCC(=O)Nc2ccccc21 +c1ccc(CNc2nnc(-c3ccncc3)o2)cc1 +COc1ccc(-c2noc(CSc3nccc(=O)[nH]3)n2)cc1 +c1ccc(NC2CCN(Cc3cnc(C4CC4)s3)C2)cc1 +CCN(CC)C(=O)c1ccccc1NCC(=O)Nc1cc(C)nn1C +O=C(NCc1cccs1)c1c(F)cccc1Cl +Cc1n[nH]c(C)c1CCC(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +CCOC(=O)CC1C(=O)NCCN1Cc1cccc(F)c1F +O=C(c1cnc2sccn2c1=O)N1CCc2ccccc21 +O=C(NCc1cccc(OC2CCCCC2)c1)NCc1ccon1 +CCCC(=O)Nc1nnc(SCC(=O)N2CCCCC2)s1 +Cc1cc(NC(=O)c2nn(-c3ccccc3)c3c2CCCCC3)no1 +CC(=O)NC1CCCN(C(=O)Cc2ccc(F)cc2F)C1 +COC(=O)N1CCC(NC(=O)c2cnn(-c3ccccc3)c2C)CC1 +CN(C)c1ccc2c3c(ccc(N(C)C)c13)COC2 +CCN(CCC#N)C(=O)CN1CCOc2ccccc21 +COc1cc(OC)c(NC(=O)NC(C)CO)cc1F +COc1ncccc1NC(=O)CN(Cc1cccnc1)c1ccccc1 +COCc1cccc(CNC(=O)NCc2cnc(C)s2)c1 +CC(=O)Nc1ccc(C(=O)Nc2cccc(C)c2C)cc1 +O=C(CCNC(=O)c1ccco1)NCc1ccc(-n2cccn2)cc1 +CCNC(=O)C1(NS(=O)(=O)N2CCCCC2)CCCCC1 +Cc1ccc(CC(=O)Nc2cccc(C(N)=O)c2)s1 +CCOc1ccc(C(=O)Nc2ccc(Cn3cncn3)cc2)cn1 +C=CCN(CCc1ccccc1)C(=O)c1ccc(S(C)(=O)=O)cc1 +CCN(CC)C(=O)CSc1nnc(-c2ccccc2)n1N +CCc1cccc(C)c1NC(=O)NC(CO)c1ccccc1 +COCCn1nc(C)c(CNC(=O)c2ccc(N(C)C)c(F)c2)c1C +O=C(NCCc1ccccc1)c1csc(Nc2ncccn2)n1 +Cc1sc(-n2cccc2)c(C(=O)N2CC(C)OC(C)C2)c1C +Cc1noc(CNC(=O)C2CCN(C(=O)c3ccccc3F)CC2)n1 +O=C(NCCN1CCCCCC1=O)c1cc(=O)c2ccccc2o1 +COC(=O)c1ccc2c(c1)C(c1nc[nH]n1)NCC2 +CCOC(=O)C1C2CC(CC2O)N1C(=O)OC(C)(C)C +Cc1cccc(C(=O)NCCC(=O)Nc2ccccc2C)c1 +COc1ccc(C#CCNC(=O)c2ccc(=O)oc2)cc1 +Cc1cn2c3c(=O)[nH]c(=O)n(C)c3nc2n1CCOCCO +CCNC(=O)C(C)NC(=O)CCc1cnn(C)c1 +COc1cc(CNC(=O)C(C)C)cc(OC)c1O +Cc1cccc(NC(=O)CCSc2nnc(-c3ccoc3C)o2)c1 +COC(=O)c1ccc(F)c(C(=O)NC2CCCCC2)c1 +CCCNC(=O)c1cccc(C(=O)N2CCc3cc(F)ccc3C2)c1 +CCOC(=O)CN(C)C(=O)C(c1ccccc1)c1ccccc1 +CNC(=O)NCCNS(=O)(=O)c1ccc(OC)cc1 +COC(=O)c1cc(C)ccc1OC(=O)C1CC2CCC1O2 +Cc1cc(C(=O)N=c2sc3cc4c(cc3n2C)OCCO4)on1 +CC(C)n1nccc1NC(=O)NCc1cccc(C(N)=O)c1 +Cn1c(SCC(=O)Nc2nc3c(s2)CCC3)nnc1C1CC1 +COc1ccc(NC(=O)N2CCN(c3cccs3)CC2)cn1 +CC(C)CC1COCCN1C(=O)NCc1ccnc(OCC2CC2)c1 +Nc1[nH]nc(-c2cccs2)c1-c1ccc(F)cc1 +CC(C)c1nnc(NC(=O)c2ccc3c(ccn3C)c2)s1 +O=S(=O)(NC1CCC(O)CC1)c1cccc2cnccc12 +CC(=O)N1CC(C(=O)Nc2nc(C(C)C)cs2)C1 +CC(=O)c1ccc(NC(=O)N2CCOCC2CC(C)C)cc1C +N#Cc1cccc(-n2c(C3CC3)nc3cc(N)ccc32)c1 +CCc1cccc(C)c1NC(=O)Cn1nc(C)ccc1=O +CC(=O)NCCNC(=O)Cc1ccc2ccccc2c1 +COc1cc(O)ccc1-c1nnc(-c2nonc2N)o1 +CC(=O)Nc1cccc(NC(=O)Nc2ccc(F)cc2F)c1 +O=C(CCc1ccco1)NC1CCCc2nc(-c3ccccc3)ncc21 +Cc1ccncc1NC(=O)N(CCO)CCN1CCOCC1 +Cn1cc(CNc2cccc(Cn3cnnc3)c2)c(-c2ccccc2)n1 +O=C(c1ccccn1)N1CCC(C(O)c2ccc(Cl)cc2)CC1 +C#CCN1C(=O)C(O)(CC(=O)c2ccc(N(C)C)cc2)c2ccccc21 +CCSc1nnc(NC(=O)c2nc(-c3cnccn3)no2)s1 +Cc1c(C(=O)OC(C(N)=O)c2ccccc2)oc2ccccc12 +O=C(NCc1ccncc1)N1CCC2(C1)OCCO2 +Cc1nnc(CNC(=O)Nc2ccc(F)cc2F)n1C1CC1 +COc1ccc(CCCNC(=O)N(C)CC2CCCO2)cc1 +Cn1cc(N2CCN(CC=Cc3ccc(F)cc3)CC2=O)cn1 +CCC(C)Nc1nnc(-c2sc(COC)nc2C)s1 +O=C(NCc1ccc(F)c(F)c1)c1cn(-c2cccc(Cl)c2)nn1 +CN(CCOCC1CC1)C(=O)Cc1c[nH]c2cc(Cl)ccc12 +CN(C(=O)C1(c2ccc3c(c2)OCCO3)CCCC1)C1CC1 +O=C(NCCCn1cccn1)Nc1ccccc1Cl +COC(=O)c1ccn(COc2ccc(Cl)cc2)n1 +CC(O)(CNC(=O)Cc1ccc(F)cc1)c1ccco1 +CC(NC(=O)NCc1ccc(Br)cc1)c1ccncc1 +CN(C(=O)c1ccc(-n2ccnc2)nc1)c1ccc2ccccc2c1 +Cc1nonc1CC(=O)NC1CC(=O)N(C2Cc3ccccc3C2)C1 +O=C(COc1ccccc1)Nc1nnc(-c2ccc(F)cc2F)o1 +Cc1ccn2c(=NC(=O)CCc3cnn(-c4ccccc4)c3)[nH]nc2c1 +Cc1ccc(NC(=O)Cc2c(F)cccc2Cl)nc1 +COCc1cccc(C(=O)NCc2cccc(NC(C)=O)c2)c1 +Cc1cc(NC(=O)NC(c2cccs2)C2CCCC2)n(C)n1 +COc1ccc(C(=O)N(C)C2CCCN(c3ccccc3)C2=O)nn1 +COc1cc(=O)[nH]c(SC(C)C(=O)NC2CCCCC2)n1 +Cn1ccc(C(=O)N(CCC(N)=O)c2ccccc2)cc1=O +CCCc1ccc(-c2nnn(-c3cccc(O)c3)c2N)cc1 +Cc1csc(NC(=O)CCCNC(=O)C2Cc3ccccc3O2)n1 +COCCCNS(=O)(=O)c1cc(C)c(C)cc1OC +O=C(CNC(=O)c1ccc2c(c1)OCO2)c1ccccc1 +COc1ccc(C)cc1C(O)CCCC(=O)N(C)C +O=C(Cn1ccc2ccc(N3CCOCC3)nc21)NCC1CCCO1 +CC(C)(C)OC(=O)N1CCCC1CNS(=O)(=O)N1CCOCC1 +O=S(=O)(NCC1CCOCC1)c1ccccc1F +NS(=O)(=O)c1ccc(Cl)c(C(=O)N2CC(O)C2)c1 +Cc1nn(C)c(C)c1CCN(C)C(=O)Nc1ccc(F)cc1 +CC1Sc2ccc(C3CCC(=O)C3)cc2NC1=O +CCCn1nc(C)c(CNC(=O)Nc2ccc3c(c2)COC3)c1C +CC1CCc2c(sc(=O)n2Cc2nnc(C3CC3)n2C)C1 +COc1ccccc1-c1cc(C)n(C)c(=O)c1C#N +OCc1ccc(-c2nccn2-c2ccc3cn[nH]c3c2)o1 +Cn1cc(NC(=O)COc2ccc(C(F)(F)F)cc2)cn1 +CC(Oc1ccccc1Cl)C(=O)NC1CCC(=O)NC1 +COc1ccc(NC(=O)Nc2cccc(C)c2)cc1NC(C)=O +O=C1CCC(C(=O)N2CCc3c(Br)ccc(F)c3C2)N1 +O=C(c1cccc(O)c1)N1CCN(Cc2cnc(C3CC3)s2)CC1 +CC(=O)NC1CCCN(C(=O)Nc2ccc(F)c(C(F)(F)F)c2)C1 +CCc1nc(CC(=O)Oc2cccc(NC(C)=O)c2)cs1 +CC(NC(=O)c1nc2c(O)cccc2s1)c1ccccc1 +CC(C)CCNc1nc2c(c(=O)[nH]c(=O)n2C)n1C(C)C +CCCOc1ccccc1OC(=O)Cn1cnc2sccc2c1=O +CCc1nc2c(c(=O)c3ccccc3n2C)c(=O)n1C1CCCC1 +Cc1ncc(C(=O)OCCCn2c(C)nc3ccccc32)c(C)n1 +CC(C)OCCOC(=O)c1cn(C)nc1-c1cccs1 +Cn1nccc1CNC(=O)Cc1csc(N2CCNC2=O)n1 +Cc1ncc2c(n1)CCC(NC(=O)c1c(F)c(F)cc(F)c1F)C2 +Cc1ccc(CNC(=O)CNC(=O)OCC(F)(F)F)cc1F +CC1(NC(=O)c2cnn3cccnc23)CCCCCC1 +CCN(C(=O)CN(C)S(C)(=O)=O)c1ccccc1 +COC(=O)c1c(C)n(-c2ccc(C)cc2)c2ccc(O)cc12 +Cc1nc2nc(N)nn2c(C)c1CC(=O)N1CCCC(C)CC1 +CCC(CO)NC(=O)Nc1ccc(CCN2CCOCC2)cc1 +CCN(CCO)C(=O)Nc1c(C)cccc1C(=O)N1CCCC1 +CC(Oc1ccccc1)C(=O)N1CCC(CCC(=O)NC2CC2)CC1 +CCC(=O)N1CCC(C(=O)c2cc(F)ccc2OC)CC1 +Cc1nn(C)c2ncc(NC(=O)c3cc4ccccc4s3)cc12 +NC(=O)C1CCCN1C(=O)COc1ccc(F)cc1F +O=C(c1cccnc1)N1CCN(C(=O)c2scnc2C2CC2)CC1 +COCCN(Cc1ccco1)S(=O)(=O)c1ccc(F)c(F)c1 +O=C(NCc1cc2cc(F)ccc2s1)NCC1(CO)CC1 +O=C(Oc1cccc(NC(=O)C2CC2)c1)c1cnn(-c2ccccc2)n1 +CC(Oc1ccc(S(C)(=O)=O)cc1)c1nnnn1-c1ccccc1 +COCC(=O)N1CCCn2cc(-c3ccccc3F)nc21 +CC(Sc1nc2ncccn2n1)C(=O)N(C)Cc1cccc(F)c1 +CCOC(=O)c1nc(C)c(Br)c(C)c1C#N +COc1ccc(OCC(=O)N2CCNC(=O)CC2)cc1 +Cc1nn(C)c(C)c1CNc1cnn(Cc2ccc(Cl)cc2)c1 +CCOC(CC)C(=O)N1CC2CC3CC(C2)CC1C3 +Cn1cc(C(=O)Nc2ccccc2F)c(C(F)(F)F)n1 +COc1ccc2cc(C(=O)c3cnn(C)c3)oc2c1 +COc1cc(Nc2c3c(nc4ncnn24)CCCC3)cc(OC)c1 +C=C(C)CSc1ccc(S(=O)(=O)N2CCCC2)cn1 +CC(C)CC(=O)Nc1ccc(Nc2ccc3nnnn3n2)cc1 +CC#CCSc1nnnn1-c1cccc(NC(C)=O)c1 +CC(C(=O)NC1CCCCCC1)N1CCN(CCO)CC1 +COc1ccccc1OCC(=O)N1CC(C)OC(C)C1 +C=CCNC(=O)Nc1cc(OC)c(OC)cc1Br +Cc1cc(C(=O)N2CC(C(=O)N(CC(C)C)CC(C)C)C2)no1 +Cc1cnc(C(=O)N2CCOC(c3cccc(OC(F)F)c3)C2)cn1 +Cn1cc(CCC(=O)Nc2cc(S(C)(=O)=O)ccc2Cl)cn1 +CCCS(=O)(=O)N1CCC(Oc2ccccc2Cl)CC1 +COc1ccc(CNc2cnn(CC(F)(F)F)c2)cc1OC +Cc1nn2ccccc2c1C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +COc1cc(C)c(C(=O)Nc2ccccc2-n2ccnc2)cc1OC +COc1ccccc1N1CCN(CC(=O)Nc2cc(C)ccn2)C1=O +NC(=O)N1CCCC(C(=O)Oc2cccc3c2CCCC3)C1 +Cc1n[nH]c(C)c1CCN(C)C(=O)C(c1cccc(F)c1)N(C)C +CCCCN1C(=O)C2(CC(=O)Nc3[nH]ncc32)c2ccccc21 +CNC(=O)NC(C)CCc1ccc(Br)cc1 +CCn1c(SCc2nc(-c3nc[nH]n3)no2)nnc1-c1ccco1 +CN1C(=O)CC(C(=O)NCc2ccsc2)c2ccccc21 +CNC(=O)NCC(=O)NCc1ccc(F)cc1C(F)(F)F +O=c1oc(-c2ccccc2)nn1CC(O)COc1ccccc1F +CCC(C)NC(=O)c1cccc(S(C)(=O)=O)c1 +CCCCNC(=O)C1CCCN(C(=O)NCc2ccc(C)s2)C1 +CCn1c(C(=O)N(CCC#N)Cc2ccco2)cc2ccccc21 +Cc1[nH]c(=O)[nH]c(=O)c1NC(=O)c1cccc2ccccc12 +COC(=O)C1CCCC1NC(=O)Nc1cccc(COC(C)C)c1 +Cc1cc(NCc2ccccn2)n2ncc(-c3ccc(F)cc3)c2n1 +O=C(Nc1cccc(-c2cn3ccsc3n2)c1)c1ccco1 +CCCC(=O)Nc1cccc(NC(=O)NCc2ncc[nH]2)c1 +Cn1nc(-c2ccc(F)cc2)cc1C(=O)NCc1cnn2ccccc12 +O=C(OCc1nc(-c2cccc(F)c2)no1)c1cccnc1 +COc1cccc(-c2c(C#N)nnn2CCC(C)C)c1 +Cc1ccc(C2CC2C(=O)N2CCCC2c2cnn(C)c2)cc1C +CCc1nc(C(=O)NCc2ccnc(OC3CCC3)c2)c[nH]1 +O=C(NCC1Cc2ccccc2O1)c1cnc(C2CCCO2)s1 +O=C(NCC(O)c1ccco1)Nc1cccc(NC(=O)C2CC2)c1 +CCN(C(=O)CS(=O)(=O)c1nc(C)cs1)C1CC1 +Cn1cc(C(=O)Nc2c[nH]cc(Br)c2=O)ccc1=O +COC(=O)Nc1nc(CC(=O)Nc2ccccc2OC)cs1 +O=C(CNc1ccccc1-n1cccn1)Nc1cc(F)ccc1F +N#Cc1nsc(C(=O)Nc2ccc(F)cc2)c1N +O=C(Cn1ccnc1)OC(c1ccccc1)c1ccccc1 +CCCn1nnc2cc(C(=O)Nc3cc(OC)ccc3OC)ccc21 +CCCOC1CCCN(C(=O)c2cccc(OC)c2F)CC1 +O=C(Cc1ccc(F)c(F)c1)Nc1cccc(C(=O)NC2CC2)c1 +O=C(c1ccc2c(c1)OCCCO2)N1CCCC1Cn1cccn1 +NC(=O)C1CCN(C(=O)c2csc(-c3cccs3)n2)CC1 +COc1ccccc1-n1c(N)c(C#N)c2c(c1=O)CCCC2 +COc1cc(O)c2c(c1)C(c1ccc(C#N)cc1)NCC2 +Nc1ccccc1NC(=O)CSc1ccccc1Br +Cc1ccc(Cc2nnc(NC(=O)COc3ccccc3)o2)c(C)c1 +O=C(Nc1cccc(F)c1)NC1CC(=O)N(c2ccc(Cl)cc2)C1 +CC(=O)Nc1cc(NCc2noc(-c3ccoc3)n2)ccc1F +CCOc1cc(N2CCN(CC(F)(F)C(F)F)CC2)ncn1 +COc1ccc2ccn(CC(=O)NCc3ccc(C)cc3)c(=O)c2c1 +CCn1c(C2CCN(Cc3ccsc3)C2)nc2cccnc21 +Nc1nonc1C(=O)Nc1cccc(N2CCCC2=O)c1 +Cc1cscc1NC(=O)NCCC1(C)OCCO1 +COc1ccc(F)cc1NC(=O)c1ccc(Br)cn1 +Cc1ccc(-c2ccnc(NC3CCNC3=O)n2)c(C)n1 +O=C(c1ccccc1F)N1CCCN(C(=O)c2ccccc2F)CC1 +COC(=O)c1ccc(CN(C)C(=O)Nc2ccncc2)cc1 +CC1CN(C(=O)c2cccc(N3CCCC3=O)c2)CCO1 +CC(=O)c1ccc(S(=O)(=O)NC(c2cccs2)C2CC2)cc1 +CC(COc1ccc2cc(Br)ccc2c1)C(N)=O +CC(=O)Nc1cc(NCc2ccc3c(c2)OCCO3)ccc1C +CS(=O)(=O)NCCOc1ccc2nnc(-c3ccccc3)n2n1 +O=C(CCc1nc(-c2ccccc2)no1)N1CC2CCCC2(CO)C1 +Nc1cc(=O)[nH]c(Cc2c(Cl)cccc2Cl)n1 +Cc1n[nH]cc1NS(=O)(=O)c1c(Cl)cc(Cl)cc1Cl +O=C(CN1CCN(C(=O)N2CCCC2)CC1)NC1CCCC1 +CCC(C(=O)OC)N(C(=O)c1scnc1C)c1ccccc1 +CCn1nc(C(=O)NCCO)c(=O)c2cc(Cl)ccc21 +FC(F)Oc1ccccc1-c1nc(C2CCOC2)no1 +Cc1cc(C)nc(-n2nc(-c3ccccc3)cc2N)n1 +CC(C)(NC(=O)Cn1cnnn1)c1ccc(F)cc1Cl +Cc1cccc(CN2CCN(C(=O)c3ccc[nH]3)CC2)c1 +CN(C)c1nnc(-c2ccc(Br)cc2)o1 +COc1ccc(CNc2ncnc(N3CCOCC3)c2N)cc1 +Cc1ccccc1-c1cnnc(NCCc2cnccn2)n1 +O=C(NCc1cccc(O)c1)c1ccc(Br)cc1O +COc1ccc(CNC(=O)c2ccc(F)c(F)c2)cc1F +O=C(c1cc(O)ccc1O)c1coc2ccc(O)cc12 +O=S1(=O)COCCN1Cc1ccccc1OC(F)(F)F +C=CCn1c(C)nnc1SCc1cccc(F)c1 +COc1cc(Cl)ccc1C(=O)NCC1COCCO1 +Cc1ccc(NC(=O)c2cc3c(C)nn(C)c3s2)c(O)c1 +O=C(CCCc1nc2ccccc2s1)N1CCCC1 +CC(C)NC(=O)C1CN(c2ncnc3c2nnn3C)C1 +CCCCCC(=O)N1CCCN(C(=O)c2cccc(Cl)c2)CC1 +CN(C)C(=O)c1cn(-c2ccccc2)c(=O)c2ccccc12 +COc1ccc(F)cc1NC(=O)NCC(C)C(=O)OC(C)C +CCOC(=O)NC1(NCC(C)C)Oc2ccccc2O1 +COc1ccc(S(=O)(=O)C(C)C(=O)NC2CC2)cc1 +COCCC1NCCc2cc(OC)c(Cl)cc21 +CCC(=O)Nc1ccc(C(=O)N2CCc3ccccc32)cc1 +CC1CCN(C(=O)c2cccc(C(F)(F)F)c2)CC1 +COc1ccc(NC(C)=O)cc1NC(=O)c1ccc2c(c1)OCO2 +O=C(NCc1ccncc1)Nc1ccn(-c2ncccc2Cl)n1 +CCOC(=O)C(C)(C)n1cc(NC(=O)Nc2cnccc2C)cn1 +Cc1cc(C(=O)OC(C)c2ccccn2)c2c(C)nn(C)c2n1 +Cc1nccn1-c1ncccc1NC(=O)CCOc1ccccc1 +COC(=O)c1cccc(C(=O)Nc2ccc(F)cc2C)n1 +CC(C)c1cccc(OCC(=O)C(C#N)c2ccccn2)c1 +O=c1[nH]c2ccccc2nc1CCc1n[nH]c(CCc2ccccc2)n1 +Cc1ccccc1S(=O)(=O)N1CCn2c(nnc2C(F)(F)F)C1 +Cc1ccc2ncc(CN(C)C(C(N)=O)c3cccc(F)c3)n2c1 +Cc1ccc(C(N)=O)c(-c2ccccc2C(=O)NC(C)C)n1 +Cc1cc(C(=O)Nc2nnc(-c3cc(C)n(C)n3)o2)c(C)o1 +O=C(Nc1ccc(CN2CCOCC2)cc1)C1CC=CC1 +COc1ccc(C(O)c2cc(C)c3c(c2)C(C)C(=O)N3)cc1 +CCOC(=O)C(C)(O)CNC(=O)Nc1ccccc1C(F)(F)F +COc1cc(OC)cc(-c2nc(CC#N)c(C)o2)c1 +N#Cc1ccc(CN(Cc2cccnc2)CC2CCCO2)c(F)c1 +CCC1CN(C(=O)C2(C#N)CCCC2)CC1N1CCOCC1 +NS(=O)(=O)C(F)(F)C(F)(F)OC(Cl)(Cl)Cl +CC(=O)NC1(c2noc(C3(Cc4ccccc4)CCC3)n2)CCCC1 +CCCOc1cccc(CC(=O)Nc2c(C)noc2CC)c1 +CCNC(=O)N1CCC(c2nnc(C3CC3)s2)CC1 +O=C(c1cc(-c2ccc(Cl)cc2)[nH]n1)N1CCC2(CC1)OCCO2 +CCOc1ccc(C(=O)N(C)C2(C(=O)OC)CCCCC2)cn1 +COC(=O)Cn1nc(-c2ccccc2)cc(C(F)(F)F)c1=O +Fc1c(Cl)ccc2c1C(c1ccc[nH]1)NCC2 +Cc1cc(NC(=O)c2ccccc2C(=O)c2ccc(F)cc2)n(C)n1 +C#CCC(OC(=O)c1ccc2nncn2c1)c1ccccn1 +O=C(C1CCOc2ccccc21)N1CCOc2cccc(F)c21 +Cc1ccc(-n2ccnc2SCC#N)cc1Br +Cc1cccc(NC(=O)C2CC(=O)N(C(C)(C)C)C2)n1 +Cc1cccc(NC(=O)c2c(C)cc(C)nc2SCC(N)=O)c1 +NC(=O)c1ccc(Cl)c(NC(=O)c2cccc(F)c2)c1 +Cc1ccc(C(=O)C2CCN(C(=O)NCC3CCCO3)CC2)cc1 +N#Cc1ccc(C(=O)N2CCN(Cc3nc4ccccc4[nH]3)CC2)cc1 +CCOC(=O)c1c(C)c(S(=O)(=O)NC2CCCC2)c(C)n1C +CCNC(=O)C1CCN(C(=O)c2ccc(C#N)cc2)CC1 +COc1ccc(-n2cnnc2SCC(=O)N2CCCCCC2)cc1 +O=C(C1CC2CCC1C2)N(Cc1cccnc1)C1CC1 +Cc1cc(C)n2nc(C(=O)NC3CCc4nnc(C)n4C3)nc2n1 +NC(=O)Cn1nnc(-c2cccc(NC(=O)C3CCC3)c2)n1 +Nc1cc(S(=O)(=O)NCC2COCCO2)ccc1O +CN(C)C(=O)CSc1nnc(-c2ccco2)n1CC1CCCO1 +CNC(=O)NC(C)(C)C(=O)N1CCC2(CC1)OCCO2 +CCNC(=O)NC1(C(=O)N2CCOC(c3ccccc3)C2)CCCC1 +CCC(CC)(CO)NC(=O)c1ccc(C)cc1O +CCc1ccc(CNCCc2nc(C)cs2)cc1 +O=C(NCC(O)c1cccc(F)c1)c1ccc[nH]c1=O +Nc1nc(N)nc(COC(=O)c2ccc3c(c2)OCCO3)n1 +Cn1cc(C2NCCc3c(F)ccc(C(F)(F)F)c32)cn1 +Cc1ccc(-c2nnc(C(=O)NCC(C)C)n2C)cc1 +CCSc1ccc(-c2cn3cc(N)ccc3n2)cc1 +Cc1ccc(NC(=O)C(C)c2ccsc2)c(F)c1 +O=C(Nc1ccc(F)cc1)c1n[nH]c2c1CCCCC2 +NC(=O)c1cccc(OCC(=O)Nc2ccc3c(c2)COC3)c1 +COc1ccc2c(CC(=O)NCCCN3CCCC3=O)coc2c1 +COc1cc(Cl)ccc1CNC(=O)N1CC(C)OC(C)C1 +COCCn1c(SCC(=O)NC2CC2)nc2ncccc2c1=O +Cc1nn(C)cc1C(=O)Nc1ccc(Cl)c(Br)c1 +CCN(CCO)C(=O)CCC(=O)c1cc(C)ccc1C +CCOC(C)C(=O)N1CCCc2cccc(OC(F)F)c21 +FC(F)(F)c1nnc2ccc(N3CCc4ccccc43)nn12 +COc1cccc(SC(C)C(=O)NC(C)C)c1 +CCC(=O)N1CCN(c2ccc(NCc3ccccc3)nn2)CC1 +CC1CCCN(S(=O)(=O)c2ccccc2F)CC1 +Cc1cccc(C2NCCc3cc(Cl)cc(Cl)c32)n1 +O=C(NC1CCCc2cn(C3CCCC3)nc21)c1cnccn1 +CCOC(=O)c1ccc(CNC(=O)C2CCC2)cc1 +CC(NCC(F)(F)F)(C(N)=O)c1ccc(OC(F)F)cc1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1ccccc1 +O=C(NCc1nc(-c2cccs2)no1)c1ccc2c(c1)OCO2 +CCC(NC(=O)c1ccc(C)[nH]c1=O)c1ccccc1OC +CC1c2ccccc2OC1C(=O)Nc1cccc(-c2cn[nH]c2)c1 +C=CCOC1CN(S(=O)(=O)c2cccs2)C2COCC12 +CN(c1ccccc1C(=O)Nc1ccccc1)S(C)(=O)=O +COc1ncccc1CNC(=O)c1ccc(Cl)c2cccnc12 +COCC1CCCN1C(=O)CCc1scnc1C +CCCC(C)C(=O)Nc1cc(C(=O)N(C)C)ccc1C +CC1(C(N)=O)CN(C(=O)Cc2ccc3c(c2)CCC3)CCO1 +O=C(CN1CCCCCC1=O)N1CCCCCC1 +Cc1ccc2ncc(C(=O)NCCNS(C)(=O)=O)n2c1 +CC1(C)CC1C(=O)NC1CCCN(c2ccccc2F)C1=O +Cc1ccccc1CNc1ccc2c(c1)OCC(=O)N2CC(N)=O +CCCC1CN(C(=O)c2c(F)cc(C#N)cc2F)CCO1 +NC(C(=O)NCCO)c1ccccc1C(F)(F)F +O=S(=O)(c1ccccc1)N1CCCC(Cc2cccnc2)C1 +CN(C)c1ccc(-c2noc(CCNC(=O)c3ccco3)n2)cc1 +COCc1cccc(NC(=O)N(C)CC(O)COC)c1 +O=C1CCC2(CCCN(C(=O)c3ccc(CO)cc3)C2)CN1CCO +CN1CC(C(=O)NC(CN2CCOCC2)c2ccccc2)CC1=O +NC(=O)NCCC(=O)NCC(c1ccc(F)cc1)N1CCOCC1 +CN1CCN(C(=O)C2CCCN2C(=O)Cc2cccc(O)c2)CC1 +Cc1cc(C(=O)Nc2ccc(C(N)=O)cc2)ccc1N +COc1cccc(-c2ocnc2C(=O)N2CCN(C)CC2)c1 +CCCN(CCO)S(=O)(=O)c1ccc(CC)cc1 +N#Cc1cccc(CN2C(=O)CNc3ccccc32)c1 +Fc1ccc2[nH]c3c(N4CCOCC4)ncnc3c2c1 +CCC(CO)N(Cc1ccccn1)C(=O)C1Cc2ccccc2C1 +CC(=O)Nc1ccc(C(=O)Nc2cc(C)nn2C)cc1 +Cc1cc(NC(=O)c2nn(-c3ccccc3F)c(C)cc2=O)ccn1 +COCC(C)N1CCN(C(=O)CCC(=O)c2ccc(C)c(C)c2)CC1 +COC(=O)N(C)c1ccc(NC(=O)c2cc3c(s2)CCC3)cc1 +O=c1[nH]nc2cc(N3CCN(c4ccccc4)CC3)ncn12 +CC(NC(=O)c1cc(=O)c2ccccc2o1)c1ccccn1 +CC(NC(=O)N1CCCC(NS(C)(=O)=O)C1)C1CC1 +CCC(=O)c1cc(-c2nc3ccccc3n2C)n(C)c1 +Cc1[nH]ncc1CCCNc1ncnc2ccsc12 +CCOc1cccc(CCNC(=O)NCc2ncn(C)n2)c1 +CCCCc1noc(CNc2cc(C#N)ccc2C)n1 +CS(=O)(=O)NCC(=O)NCC1CCN(c2ccc(F)cc2)C1 +N#Cc1ncn(CCCOc2ccc3c(c2)OCO3)n1 +Cn1nc(C(=O)Nc2ccc3c(c2)NC(=O)CC3)c2ccccc2c1=O +COCCN1CCN(C(=O)c2ccc(F)cc2C)CC1=O +Cc1ccc(OCC(O)CN2CCN(C(=O)c3ccco3)CC2)cc1 +N#Cc1ccccc1N1CCCN(C(=O)Nc2ccncc2)CC1 +CS(=O)(=O)N1CC2OCCN(c3cnccn3)C2C1 +CCC(C)C(=O)Nc1cc(OC)c(OC)cc1C(N)=O +C#Cc1cccc(NC(=O)c2ccc(-n3nccc3C)cc2)c1 +CCOC(=O)NCCC(=O)N1CC(C)c2ccccc21 +Cc1ccc(NC(=O)Nc2cc(S(=O)(=O)N(C)C)ccc2C)cc1 +COc1ccc(-c2nc(CCO)c(C)o2)cc1OC +Cc1nn(-c2ccc(F)cc2)c2[nH]nc(NC(=O)Cn3cnnn3)c12 +COC(=O)CN(C(=O)COc1ccc(C)cc1C)C(C)C +CC(C)C(=O)N1CCCC1C(=O)NCc1ccncc1 +CCCCc1ccc2c(c1)S(=O)(=O)N=C(NCCOC)N2 +O=C(NC1CCN(C(=O)c2ccco2)CC1)c1ccnc2ccccc12 +CC(Cn1ccnc1-c1cnc(-c2ccco2)nc1)Oc1cccnc1 +CCC(C)C(NC(=O)OCc1ccccc1)C(=O)N1CCC(O)CC1 +Cc1cc(NC(=O)NC2(c3noc(C)n3)CCCCCC2)no1 +C=CCNC(=O)c1ccc(NC(=O)CSc2ccccc2C)cc1 +O=C(NCCN1CCN(C(=O)c2ccsc2)CC1)C1CC1 +CNC(=O)NCC(=O)N1CC2CCCCC21c1ccccc1 +Cc1cc(=O)oc2c1cc(OCC(=O)NC(C)C)c1occ(C)c12 +CCc1cc(=O)n2nc(C3CCCN(C(=O)c4ccco4)C3)cc2[nH]1 +CC(=O)N1CCC(NC(=O)Cc2ccc(-n3cccn3)cc2)CC1 +NS(=O)(=O)N1CCN(Cc2csc3ccccc23)CC1 +O=C(CSc1nncs1)Nc1ccc(F)cc1Br +O=C(CSc1ccc(F)cc1)N1CCn2c1nc1ccccc12 +CC(C)CCOCCS(=O)(=O)c1ccccc1N +CC1CN(Cc2ccc(C(=O)N3CCOC(C)(C)C3)cc2)CC(C)O1 +Cc1cc(C)n2cc(CN3CCN(S(N)(=O)=O)CC3)nc2n1 +Cc1ccc2c(NC(=O)C3CN(C(=O)c4cnccn4)C3)cccc2n1 +CCCc1noc(CNc2cc(S(C)(=O)=O)ccc2F)n1 +CCNC(=O)c1ccc(NC(=O)Cc2ccc(C)nc2)c(C)c1 +COc1ccc(C2NC(=O)c3c(cnn3C)N2)cc1 +O=C(Cn1nnc2ccccc2c1=O)NCCn1ccc2ccccc21 +CC(C)C1(c2ccccc2)Nc2ccccc2C(=O)N1C +COc1ccc(CC(=O)Nc2sc(C)c(C)c2C#N)cc1F +CCc1ccc(NC(=O)Nc2ccc3c(c2)CC(=O)N3)cc1 +Clc1cc(Cl)c2c(c1)C(c1ccncc1)NCC2 +CCc1cc(N2CCN(C(=O)c3nnc(COC)o3)CC2)ncn1 +O=C(COc1ccccc1)Nc1ccn(CCc2ccncc2)n1 +Cc1cc(C(=O)N(C)CCC(F)(F)F)c(C)n1C(C)C +COc1ccnc(NC(=O)c2ccc3c(c2)OCO3)c1 +CC(=O)c1cccc(NCc2ccncc2Cl)c1 +COC(=O)c1ccc(C)c(NC(=O)c2cn[nH]c2)c1 +CC(C)(CNc1cn[nH]c(=O)c1Cl)c1ccc2c(c1)OCO2 +CCOc1ccc(F)c(C(=O)Nc2ccn(-c3ccccc3)n2)c1F +CC(C)S(=O)(=O)NCC(O)c1ccc2c(c1)CCO2 +CC(C)c1csc(C(N)c2cc(F)c(F)c(F)c2)n1 +Cc1ccc(CN(C)C(=O)c2scnc2C)o1 +CCc1cc(NCc2nnc3n2CCCC3)n2nccc2n1 +O=C(NC1CCN(C(=O)C2(c3ccccc3)CC2)CC1)c1cccnc1 +CCc1ccc(NC(=O)NCc2ncoc2C)cc1 +COc1cc(N2CC3OCCN(C(=O)c4ccco4)C3C2)ncn1 +CN(CCc1ccccn1)C(=O)CNC(=O)Cc1ccc[nH]1 +CN1C(=O)Cc2cc(S(=O)(=O)NCCC(N)=O)ccc21 +CCN(CC(C)C#N)C(=O)CNc1cc(Cl)ccc1C(=O)NC +Cc1ccc(C(=O)N2CCc3ccccc3C2CO)n1C +Cc1ccc(C)c(OC(=O)c2ccc(=O)n(C)n2)c1C +CCCNC(=O)CCNC(=O)NC(C)c1ccc2c(c1)CCCC2 +CCc1nc(CC(=O)Nc2ccc(F)cc2C)cs1 +O=C(CN1CCN(c2ccc(Cl)cc2)C1=O)NCc1ccccn1 +CCN(C(C)=O)c1nc(CNc2cnn(-c3ccccc3)c2)cs1 +O=C1CCCCCN1CCCNC(=O)C1(c2ccc(F)cc2)CC1 +O=C(CN1CCN(c2nccs2)CC1)Nc1ccc(Cl)cn1 +CC(C)CC(=O)NCc1ccc(-n2cncn2)cc1 +CCOC(=O)CN(CC)C(=O)c1cc(F)cc(Br)c1 +COc1ccc(Cc2nc3cc4c(cc3n2CC#N)OCO4)cc1 +COC(=O)c1ccccc1NC(=O)CNc1ccc(C#N)cc1 +Cc1cccc(NC(=O)C2Cc3ccccc3C(=O)O2)c1C +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)C1CCCO1 +CC=CCn1c(=O)c2c(nc3n(CC(C)C)c(C)c(C)n23)n(C)c1=O +Cc1cc(C)c(C)c(C(=O)N2CCN(CCO)CC2)c1C +CC(C)(C)CC(=O)N1CCCC1C(=O)NC1CC1 +N#CC1CCN(C(=O)CCc2ncc(-c3c(F)cccc3F)o2)CC1 +O=C1COc2ccc(CO)cc2N1CC(O)CO +O=C(CC1C=CCC1)Nc1ccc2ccccc2n1 +Cc1ccc(C)c(CNC(=O)CCn2ccc(C)n2)c1 +Cn1ncc2c(=O)[nH]c(C=Cc3cc(Cl)c4c(c3)OCO4)nc21 +CCn1c(=O)c2ccnn2c2ccc(C(=O)NC3CCCC3)cc21 +CC(Sc1nncn1C(C)C)C(=O)N(C)c1ccccc1 +CCOC(=O)c1ccccc1NC(=O)c1ccc(N)cc1Cl +CCOC(=O)c1ccc(NC(=O)Cc2nonc2N)cc1 +CCNc1cc(S(=O)(=O)N2CCCCCC2)ccn1 +Cc1noc(CCC(=O)Nc2cccc(OCC(F)(F)F)c2)n1 +Cc1nc(NC(=O)COCC2CC2)ccc1Br +O=C(c1cccc(Cl)c1)N1CCOCC1C1CC1 +COc1cccc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)c1 +COCc1ncc(-c2c(C)c(-c3ccc(O)cc3)nc(N)c2C#N)cn1 +CCCNc1ccc(C#N)cc1NC(=O)CCc1c(C)nn(C)c1C +Cc1csc(NC(=O)c2ccccc2S(C)(=O)=O)n1 +O=C(CCc1c[nH]c2ccccc12)N1CCCCC1C1OCCO1 +CN(Cc1ccccn1)C(=O)c1ccccc1OC1CCC1 +CCN(Cc1noc(C2CCC2)n1)C(=O)c1ccc2oc(C)cc2c1 +C=CCNC(=O)C1CCN(c2ccc3nncn3n2)CC1 +CC(CC#N)NC(=O)c1cccc(OC(F)F)c1 +CCOc1ncccc1NC(=O)c1ccc(C)nc1 +CC1CC(c2ccc(F)cc2)CN1C(=O)CCCCNC(N)=O +O=C(NC1CCc2c(Cl)cccc21)c1ccc(-n2ccnc2)nc1 +CCc1nc(C2CCCN2C(=O)C(C)Cc2c(C)noc2C)no1 +CCc1nnc2n1NC(c1cccc(OC)c1)CS2 +Cc1cc(Br)c(S(=O)(=O)n2ccnc2)cc1Cl +COc1ccccc1S(=O)(=O)Nc1cccnc1 +N#Cc1cccc(C(=O)NCCCn2ccc3ccccc32)c1 +CCOc1ccc(C(=O)Nc2cccc(O)c2)cc1 +Cc1nc2ccc(C(=O)N(C)CCC#N)cc2nc1C +Cc1ccccc1CN(C)C(=O)C(C)NS(=O)(=O)c1ccccc1 +CC(NC(=O)C1CCCN1C(=O)c1ccccc1F)c1ccccc1 +CCc1ccc(OCc2nnc3ccc(N)cn23)cc1 +O=C(Cn1cccn1)N1CCC(c2ccc3ccccc3c2)C(O)C1 +Cc1nn2cccnc2c1C(=O)NCCc1c(Cl)cccc1Cl +Cc1ccc(C)c(NC(=O)CNC(=O)c2ccc(F)cc2)c1 +Cc1ncsc1C(=O)N1CCc2noc(-c3ccccc3)c2C1 +Cc1cc(C(=O)NC(C)c2ccc(F)c(F)c2)c(C)o1 +COc1ccc(Cc2nnc(-c3ccc(N)cc3)o2)cc1F +O=C(Nc1ccc(S(=O)(=O)N2CCCC2)cc1)C1CCC1 +CCCn1nccc1NC(=O)CCOc1ccccc1 +Cn1ccnc1S(=O)(=O)CC(=O)NCc1ccc2c(c1)OCO2 +Cn1c(N)c(C(=O)COC(=O)COc2ccccc2)c(=O)n(C)c1=O +COC(=O)C(CC1=CCCCC1)(NS(C)(=O)=O)C(F)(F)F +CC(=O)c1ccc(Nc2ncccc2C(N)=O)cc1 +CC(c1nc2ccccc2c(=O)[nH]1)N(C)CC1CC1 +Cc1noc(CNC(Cc2cccs2)c2cccs2)n1 +CCN(CC)C(=O)CCSc1nnc(-c2cccc(C)c2)o1 +CC(C(=O)NCc1cccc(OCC#N)c1)c1cccs1 +CNc1nc(Cn2nc(C)nc2C)nc2sccc12 +CC(C)N(C(=O)CSc1nncn1-n1cccc1)c1ccccc1 +CCCOc1ccc(-c2cc(C)[nH]c(=O)c2C#N)cc1OC +CC(C)CC(=O)Nc1ccc(S(=O)(=O)N2CCCCCC2)cc1 +CC(C)CCNC(=O)C1(C)CCC(=O)N1Cc1ccc2c(c1)OCO2 +COc1ccc2c(c1OC)C(=O)OC2Nc1ccc(F)c(F)c1 +N#CC(NC(=O)c1ncn(-c2ccccc2)n1)c1ccccc1F +N#CCOc1ccc(NC(=O)c2cnc3ccccc3n2)cc1 +CCCCNC(=O)Cc1csc(NC(=O)c2ccc(=O)[nH]c2)n1 +CCN1CC2(CCC1=O)CCN(C(=O)c1cc(C)ccc1OC)CC2 +CCN(C(=O)c1cc2ccccn2n1)c1ccccc1 +O=C(Nc1cc(Cl)cc2c1OCC2)NC1CCCn2ncnc21 +Cc1cc(C)nc(CCNC(=O)c2cn(C3CCCCC3)nn2)n1 +CC(=O)N1CCCC(C(=O)NC(C)c2sc(C)nc2C)C1 +CN1CC(Nc2nc(-c3ccccn3)nc3c2CCC3)CCC1=O +Fc1cccc(CSc2cc(N3CCCC3)ncn2)c1 +O=c1cc(CN2CCOCC2)c2ccc(O)cc2o1 +CC1CCCC(C)C1NC(=O)Cc1cn2ccccc2n1 +Cc1ccc(C(C)NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)o1 +COC(=O)c1ccccc1-n1nc(C2CC2)c2c1CCNC2 +C=CCCC1NCCc2c(F)ccc(C(F)(F)F)c21 +Cc1ccc(-c2nnc(SCC(=O)NCC3CCCO3)n2N)cc1 +CCC(NC(=O)c1cccc(S(C)(=O)=O)c1)c1ccc(C)cc1 +COc1ccc(NC(=O)c2cnns2)cc1OCc1ccncc1 +O=C(Nc1ccnn1-c1ccccc1)C1OCCc2ccccc21 +Cc1csc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)n1 +CCc1nc(C)c(C(=O)N(Cc2ccco2)C(CC)CO)o1 +Cc1sc2ncnc(SCC(=O)NCC3CCCO3)c2c1C +CC1CCCC(C)N1C(=O)NCCc1cnn(C)c1 +C=CCn1c(=NC(C)=O)sc2cc(S(C)(=O)=O)ccc21 +CCNC(=O)C(C)NC(=O)C1CCN(C(=O)C(C)(C)C)CC1 +Cc1ccccc1C(=O)N1CC2OCCN(c3ncccn3)C2C1 +CCS(=O)(=O)N(C)CCCNC(=O)c1ccc2sccc2c1 +CCN(CC)c1nc2c([nH]c1=O)c(=O)n(C)c(=O)n2C +Cn1c(=O)c2c(ncn2CCNc2cccc3ccccc23)n(C)c1=O +Cc1onc(-c2cccnc2)c1C(=O)Nc1ccc(F)cc1Cl +COC(=O)c1cccc(C(=O)NCC2CCOC2)n1 +Cc1nn(C(C)C)c(C)c1NS(=O)(=O)c1cc(F)c(F)cc1F +CC(=O)c1nnn(CCOc2cccc(C)c2)c1C +COc1cc(-c2nccs2)cc(N)c1OCC#N +O=C(NCc1ccccc1F)N1CCCC1CCCO +CN(C)c1ncc(-c2cc(C(=O)NCCc3ccccc3)n(C)c2)cn1 +Cc1ccccc1CC(=O)Nc1cc(C#N)ccc1C +CCCNC(=O)CN(C)C(=O)CSc1nc2ccccc2[nH]1 +NC(=O)COc1cccc(-n2ccc(-c3cccs3)n2)c1 +CS(=O)(=O)N1CCCN(C(=O)CCCOc2ccccc2)CC1 +CCCNC(=O)c1nnn(-c2ccc3ncccc3c2)c1C +CC(Sc1ccc(S(C)(=O)=O)cc1)C(=O)NC(C)(C)C +OCc1ccc(CNc2ncnc3ccsc23)cc1F +CC(NC(N)=O)C(=O)NC(c1ccccc1)c1ccc(Cl)cc1 +COc1ccc(CCC(=O)N2CCN(c3nccn3C)CC2)cc1 +Nc1ccc2c(c1)CCN2C(=O)COc1ccccc1F +Cc1cccc2c(NCC3(O)CCOCC3)c(C#N)cnc12 +CC(C)(C)c1ccc(OCC(=O)NCC2(CO)CC2)cc1 +Cc1n[nH]c(SCCOc2ccccc2N)n1 +O=C1CN(C(=O)CCCOc2ccc(F)cc2)c2ccccc2N1 +CCC(C(=O)Nc1oc(C)c(C)c1C#N)n1c(N)nnc1SC +CN(C)C(=O)N1CCCC(C(=O)Nc2ccc(C#N)c(Cl)c2)C1 +Cc1cnn(C2CCCN(C(=O)c3ccc4c(c3)CCC4)C2)c1 +Cn1cc(C(=O)Nc2ccc(Cl)cc2)c(=O)c2cccc(F)c21 +O=C(NCc1cc(N2CCOCC2)ncn1)c1cccc(CO)n1 +Cc1cccc(NC(=O)CSc2nc(C)cc(C)c2C#N)c1 +COCc1noc(CN2CCC3(CCCO3)CCC2=O)n1 +Cc1nc(S(=O)(=O)NCC2CN3CCCCC3CO2)cn1C +Cc1cc(C)cc(NC(=O)CCn2nc(C)cc2C)c1 +CCOC(=O)c1ccc2c3c(cnc2c1)C(=O)NCCN3 +CC(C)Cn1cc(O)c(=O)cc1CN(C)Cc1ccccc1 +C=CCn1c(C)nnc1SCC(=O)Nc1ccc(F)c(F)c1 +COc1cccc(OCC(=O)N(C)C2CCCCC2)c1 +O=C(Cc1ccc2c(c1)OCCO2)Nc1cccnc1 +CCOc1ccc(C(=O)Nc2ccc(C)cc2C)nn1 +CCC(C)C(=O)NC(c1ccccn1)c1ccccc1OC +Cn1nccc1CNC(=O)NC(c1ccc(F)cc1F)C(C)(C)C +COc1ccc(OC)c(CCn2nc(C)c(N)c2C)c1 +N#CCCN(Cc1ccco1)Cc1ccc(F)cc1Cl +COCc1nc(C)c(C(=O)Nc2nc(C(F)(F)F)cs2)s1 +O=C(Nc1ccc(Oc2cccnc2)nc1)C1CC1c1ccccc1 +CCOc1ncccc1C(=O)Nc1ccc(C)c(C)c1 +Cc1ccc(C2OCCCC2NC(=O)c2ccoc2)cc1 +COc1cccc2c1C(c1ccc3cc[nH]c3c1)NCC2 +C=CCn1cnnc1SCC(=O)Nc1ccc(CC#N)cc1 +CC(=O)N1CCN(CCNC(=O)C2=C(C)Oc3ccccc3C2)CC1 +O=C(OCC1CCCO1)c1ccccc1C(F)(F)F +NC(=O)Nc1ccc(C(=O)COC(=O)c2cc3ccccc3o2)cc1 +Cc1cc(C)c(S(=O)(=O)NC(C)Cn2cncn2)c(C)c1 +COC(=O)c1ccc(NC(=O)c2cc3ccccc3[nH]2)cc1 +CCOC(=O)C(O)Cc1ccc(C(C)(C)C)cc1 +CC1Oc2ccc(C(O)C(N)=O)cc2N(C)C1=O +O=C(CCC(=O)NCc1ccco1)NCc1ccc(F)cc1 +CC(C)(C)c1ccc(OCc2n[nH]c(CC(N)=O)n2)cc1 +Nc1ccc2c(c1)NC(=O)C(Cc1ccccc1)S2 +Cc1ccc(S(N)(=O)=O)cc1NCC1CCCCC1 +O=C(c1ccccc1SCc1cscn1)N1CCOCC1 +CC(=O)c1cccc(Nc2ncnc(N3CCCC3)c2N)c1 +CC(=O)N1CCCC1c1cncc(Oc2ccccc2F)n1 +O=C(CCC(=O)c1ccc(F)cc1F)NCC(F)(F)F +COc1ccc(C)cc1NC(=O)C1CC(=O)N(C2CCOCC2)C1 +Cc1cccc(-c2ccc(C(=O)NC(C)C3CCCO3)c(=O)[nH]2)c1 +O=C(NCC(O)c1ccco1)c1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)C(C)(C)C)cc1NCc1noc(C2CC2)n1 +Cc1cccc(OCC(=O)N2CCN(Cc3ccco3)CC2)c1C +CCCCOCCSc1nnc(C)c(=O)n1N +COC(=O)c1cccc(NC(=O)c2cccc(OCC(F)F)n2)c1 +COCCC(=O)N1CCC(n2c(=O)n(C)c3cncnc32)CC1 +CC(=O)NCCn1ncc2c(NCc3ccco3)ncnc21 +COc1ccc(OC)c(NC(=O)Cc2cccc(F)c2)c1 +Cc1ccc(C(O)CNC(=O)c2cccc(C#N)c2)cc1 +c1cc2c(cc1COc1ccc(-n3cnnn3)cc1)OCO2 +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccc(OC)nc1 +Cc1ccc(-c2ccc(C(=O)N(C)CCO)o2)cc1 +Cc1occc1C(=O)N1CCCN(Cc2nccn2C)CC1 +Cc1cccc(N2CCN(CC(=O)N3CCCCC3C)CC2)c1C +CCc1onc(C)c1NC(=O)C(C)NS(=O)(=O)c1ccccc1 +CC1CN(C(=O)c2ccoc2)CC1c1nc(-c2ccncc2)no1 +COC(=O)C(C)CNC(=O)Nc1cccc(-n2nc(C)cc2C)c1 +CN(Cc1cccc(C#N)c1)c1ncc(Br)cc1N +N#Cc1ccc(CNC(=O)c2ccc(OCC(F)F)nc2)cc1 +O=S(=O)(NCc1cc2ccccn2n1)c1cccs1 +O=C1NC2(CCCN(C(=O)CCn3cncn3)C2)Oc2ccccc21 +COc1ccccc1NCCC(O)c1ccc(F)c(F)c1 +CC(=O)NCCc1csc2nc(-c3cccs3)nn12 +OCCN1CCN(c2ccccc2Br)CC1 +Cn1ccnc1SCC(=O)c1ccc2c(c1)NC(=O)CO2 +CC(=O)c1ccc(C#CCNS(=O)(=O)C(C)C)cc1 +COc1cccc(NCc2nn(Cc3ccc(Cl)cc3)c(=O)[nH]2)c1 +COc1c(Cl)cccc1NC(=O)NCC(C)C +Cc1cc(C)nc(-n2nc(C)cc2NC(=O)CCc2ccccc2)n1 +CC(=O)Nc1cc(NC(=O)COc2ccc(C)c(C)c2)ccc1F +CN(Cc1cnn(C)c1)C(=O)CSc1nc(-c2cccs2)n[nH]1 +CCOCC1CCCN(C(=O)C2COc3ccc(OCC)cc3C2)C1 +COCc1nn(Cc2csc(Nc3ccccc3C)n2)c(=O)o1 +COC(=O)c1cc(-c2cc(OC)ccc2OC)nn1C +O=C(CNC(=O)C1CCCCC1)Nn1cnc2ccccc21 +CC(C)(C)NC(=O)CNc1ccc(Cl)cc1C#N +N#Cc1c(-c2ccc(Cl)cc2Cl)c(C#N)c(=O)n(N)c1N +COCC(C)NC(=O)C1CCN(c2ccccc2)CC1 +CNC(=O)c1cc(NCCNS(C)(=O)=O)ccn1 +CCOC(=O)C(Cc1ncc(-c2cccnc2)o1)NC +COc1ccc(Cl)cc1NCC(=O)N1CCc2sccc2C1 +NS(=O)(=O)c1ccc(C(=O)N2CCC(c3ccc(F)cc3)C2)cc1 +Cn1cc(CNC(=O)NCC(C)(O)c2ccccc2)cn1 +CN(Cc1ncc[nH]1)C(=O)c1cc(COc2ccccc2F)[nH]n1 +CCCn1ncc(-c2ccc(Cl)cc2Cl)c(N)c1=O +CS(=O)(=O)c1ccccc1C(=O)NC1C2CC3CC(C2)CC1C3 +NC(=O)COc1cccc(C(=O)N2CCCCCC2)c1 +CCC(CO)NS(=O)(=O)c1c(Cl)cc(N)cc1Cl +Cc1c(NC(=O)N(C)CCc2ccncc2)cccc1N1CCCC1 +O=S(c1snnc1-c1ccc(F)cc1)C1CCCCC1 +Cc1noc(C(C)OC(=O)c2cnn(-c3ccccc3C)c2C)n1 +CC(C)(C)NC(=O)Cc1cc(-c2ccccc2)on1 +C=CCNC(=O)c1cc(-c2cc(C)oc2C)nc2c1cnn2C(C)C +Cc1ccc2ncc(C(=O)NC(C)c3ccc4c(c3)CCC(=O)N4)n2c1 +CCN(Cc1ccccc1C)C(=O)Nc1cnc2c(c1)c(C)nn2C +COC(=O)c1csc(S(=O)(=O)N2CCN(C(C)=O)CC2)c1 +O=S(=O)(Cc1cccc(F)c1)NCC1(c2ccc(F)cc2)CC1 +O=C(Nc1ccccn1)c1ccc(OCc2cscn2)cc1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1ccccn1 +Cc1ccc(C(=O)CSc2nc(=O)[nH]c3c2CCCC3)cc1 +Cc1noc2nc(C)n(CC(=O)NCc3cccc(Cl)c3)c(=O)c12 +Cc1cc(=O)n2nc(CN3CCN(CC(F)(F)F)CC3)sc2n1 +CC(C)(CNc1ccc(S(=O)(=O)N2CCCC2)cn1)C(N)=O +CC1CCC(NC(=O)CCC(=O)c2cccs2)CC1 +CCN(C)C(=O)c1cccc(OC(=O)C2CC2C)c1 +COC(=O)NCC(=O)N(Cc1cccc(Br)c1)C1CC1 +Nc1ccc(SCc2nnnn2-c2ccccc2)cc1 +Cc1oc(-c2cccs2)nc1COc1c(CO)cc(F)cc1CO +O=C(COCc1ccccc1Cl)N1CCC2(CC1)OCCO2 +C=CCn1nnnc1SC(C)C(=O)c1ccc(Cl)cc1 +CC(C)CN(CC(F)(F)F)C(=O)CN(C)C(=O)c1ccsc1 +Cc1cc(C)c(CNC(=O)NC2CCc3c(F)cccc32)c(=O)[nH]1 +CCNC(=O)C1CCCN(C(=O)Cc2c(F)cccc2F)C1 +COCCCN(C)C(=O)Nc1ccc(Oc2cccc(C#N)c2)cc1 +Cc1occc1-c1nnc2sc(-c3ccccc3)nn12 +O=C(Nc1nccs1)C1(c2cc(-c3ccco3)on2)CC1 +CCc1ccc(C(=O)OCc2csc(-c3ccccn3)n2)o1 +O=C(Cc1cccc(Cl)c1)N1CCCC(CO)C1 +CC(C)COC(=O)C1CCN(c2oc(-c3ccco3)nc2C#N)CC1 +Cc1nc(C)c(C(=O)OCC(=O)NC(C)C)s1 +COc1ccc(OCc2cccc(C(N)=O)c2)cc1 +COc1c(C)cc(CN(C)C(=O)Nc2cnccc2C)cc1C +Cc1cccc(NC(=O)c2onc(-c3ccccc3C)c2N)n1 +COc1cc(CNC(=O)c2ccc(N(C)CC(C)C)nc2)ccn1 +CCOc1ccccc1NC(=O)CC1Cn2nc(C)nc2NC1=O +Cc1sc(-c2ccno2)cc1S(=O)(=O)NCC1CCCO1 +COCCn1nnc(C2CN(C(=O)CN3CCOC3=O)CCO2)n1 +CS(=O)c1ccc(C(=O)OCC2CCCO2)cc1 +COc1ccc(OC)c(C(=O)N(C)C2CCC(C)CC2)c1 +CN(CC(=O)NCCc1ccccc1F)c1ncnc2[nH]cnc12 +O=C(c1c[nH]nc1-c1ccc(F)cc1)N1CCCC1Cn1cccn1 +Cc1ccc(-c2noc(-c3nnn(-c4ccc(F)cc4)c3N)n2)cc1 +CCOc1cc(C(=O)Nc2nccn(C)c2=O)ccc1C +CN(C)S(=O)(=O)NC1CCc2cc(Cl)ccc21 +Cc1oc2ncn(CC(C)C)c(=O)c2c1C(=O)N1CCC(=O)CC1 +CCC(O)(CC)CNC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +COc1ncccc1C(=O)N1CC(OCC(C)C)C2OCCCC21 +COc1cc(C)c(C(=O)CNC(=O)c2cccs2)cc1C +Cc1nn(C)cc1NC(=O)CN1CCOC(C(F)(F)F)C1 +CNC(=O)Cc1ccc(NC(=O)c2ccc(OC)cc2OC)cc1 +Cc1cc2c(c(C)c1Cl)-c1n[nH]c(C#N)c1CCO2 +Cc1noc(CNC(=O)Nc2cccc(C(F)(F)F)c2)n1 +Cc1cc(N)ccc1NS(=O)(=O)c1cccc(Cl)c1 +CCNC(=O)Cc1csc(NC(=O)c2ccc(=O)[nH]c2)n1 +C=C(C)CSc1nnc2n(C)c(=O)c3ccccc3n12 +Cc1ccnc(NC(=O)c2ccc(-n3cncn3)cc2)c1 +OCc1nc2cc(C(F)(F)F)ccc2n1CCCN1CCOCC1 +O=C(COc1cccc2ccccc12)Nc1cc(N2CCCC2)ncn1 +CC(=O)Nc1cc(Cl)ccc1NC(=O)CCC(=O)c1ccccc1 +COC(=O)C1CN(Cc2cc(C)c(C)cc2OC(F)F)CCO1 +NC(=O)C1CCN(c2cc(-c3ccccc3)ncn2)CC1 +CCCn1c(C)nnc1SCC(=O)N(C)Cc1ccccc1 +Cn1c(=O)n(CCc2ccccc2)c(=O)c2c3c(sc21)CCCC3 +COc1ccc(OCc2nc(C(C)C)c(CO)s2)cc1 +CN(Cc1cscn1)S(=O)(=O)c1cn(C)nc1N +Cc1ccc(NC(=O)N(CCCO)C(C)C)cc1Cl +CN(C)C(=O)c1ccc(C(=O)NCC(=O)Nc2ccc(F)cc2)cc1 +CCCNS(=O)(=O)c1cc(C(=O)CC)ccc1Cl +O=C1CC(C(=O)Nc2cncc(Cl)c2Cl)CN1 +CN(C(=O)CCNC(=O)c1ccco1)c1ccccc1 +COC1CCN(C(=O)COc2ccc(Oc3ccccn3)cc2)CC1 +O=C(c1ccncc1)N1CCCc2cc(Br)cc(F)c21 +CN(C(=O)c1cnn(Cc2ccccc2)c1)c1ccc(F)c(F)c1 +Cc1n[nH]c2c1C(c1ccc(N(C)C)cc1)C1=C(COC1=O)N2 +Cc1ccc(OC2CC3CN(Cc4cnn(C)c4)CCN3C2)cc1 +Cc1cccc(NC(=O)N2CCN(Cc3ccn(C)c(=O)c3)CC2)c1 +CCc1ccccc1CNC(=O)c1sc(S(N)(=O)=O)cc1C +CCc1cc(C(=O)N2CCCC(CO)(CC3CC3)C2)cs1 +Cc1ccc(NC(=O)CN(C)Cc2sc(N(C)C)nc2C)nc1 +COc1ccccc1NS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1 +Cc1cc(C)cc(NC(=O)C(C)Oc2cccc(N)c2)c1 +COc1cccc(-c2ncc(C3NCCc4nc[nH]c43)s2)c1 +CCNc1ncc(C(=O)Nc2n[nH]c(N3CCCCC3)n2)s1 +CCS(=O)(=O)N(CCCO)c1cccc(C#N)c1 +Cc1cc(C)cc(OCCN(C)C(=O)c2ccc(C)nc2C)c1 +COc1ccc(C(=O)NCCc2ccc3c(c2)OCO3)cc1OC +Cc1ccc(-n2nc(C)c(NC(=O)c3ccc(N(C)C)cc3)c2C)cc1 +CN1CCC(NC(=O)C2(c3ccc(F)cc3F)CCOCC2)C1=O +Cc1cccnc1NC(=O)c1ccc(CNC(=O)NC(C)C)cc1 +Cc1cc(C(=O)NC(C)(C)c2ccc(Br)cc2)on1 +CN(CC(=O)Nc1ccc(Br)cn1)C(=O)C(C)(C)C +O=C(COC(=O)c1cccc(O)c1)Nc1ccccc1 +Cc1cc(C)nc(CNc2cc(-c3ccccc3)nc3ccnn23)n1 +COC(=O)CNC(=O)c1cccc(COc2ccc(C)nc2)c1 +O=C(Cn1ccc2ccccc21)NCc1cscn1 +O=C1NCCN(S(=O)(=O)c2cccc(F)c2)C1c1ccccc1 +N#CC(C(=O)Nc1ccccc1)c1nccn1CC(F)(F)F +Cc1nc(-c2ccnc3c2ccn3C)cc(C(C)C)n1 +CC1=C(C(=O)Nc2cccc(C)c2)C(c2ccncc2)n2nnnc2N1 +O=C(CCc1cccs1)N(Cc1cccnc1)Cc1ccco1 +CC(=O)NCCNC(=O)Nc1ccc(Br)cc1C(C)C +CCc1nc2n(n1)CCCC2NC(=O)Nc1cccc(SC)c1 +CCC(CNS(C)(=O)=O)Oc1ccccc1C +Cc1ccc(S(=O)(=O)CCCC(=O)Nc2cccc(C)c2C)cc1 +Cc1ccc2nc(NC(=O)c3ccc[nH]c3=O)sc2c1 +CC(=O)c1c[nH]c(C(=O)Nc2ccccc2N2CCCC2=O)c1 +CN(CCc1ccccn1)C(=O)C1CC1c1ccc(C(F)(F)F)cc1 +C=CCNC(=O)C1CCCN1S(=O)(=O)c1ccc2ccccc2c1 +O=C(NC1CC(=O)N(c2ccccc2)C1)c1ccc(=O)[nH]c1 +CC(=O)NCc1ccc(-c2csc(NC(=O)c3ccoc3C)n2)o1 +CC(C)CC(=O)NCc1nncn1-c1ccccc1 +Cc1nc2cc(NC(=O)C3CCC3)ccc2n1-c1ccccc1 +CN(C)c1ccccc1NC(=O)NCc1ccnc(OC(C)(C)C)c1 +NS(=O)(=O)CC1CCN(CC(=O)OCc2ccccc2)CC1 +CN(CC1CCOCC1)c1nccnc1N(C)CC1CCOCC1 +Cc1cc(C(=O)NC2(c3ccc4c(c3)OCO4)CC2)c(C)o1 +COC(=O)c1occc1CSc1n[nH]c(=O)n1C1CC1 +Cc1cc(N2CCOCC2)nc2sc3c(=O)[nH]cnc3c12 +COC(=O)c1n[nH]c2ccc(NC(=O)c3scnc3C)cc12 +COc1ccc(C2NCCc3c(F)cc(O)cc32)cc1 +CN(CCC#N)CCSc1ccc(Cl)cc1 +CNC(=O)CCc1ccc(NC(=O)OC(C)(C)C)cc1 +CCc1cnc(N2CC3CN(c4cncnc4)C(=O)C3C2)nc1 +CCOC(=O)C1CCC(NC(=O)c2ccco2)CC1 +Cc1cc2ccccc2n1CC(=O)N1CC(C)CC(C)C1 +COc1cc(-c2n[nH]c(=O)n2C)cc(OC)c1OC +CCCCN(CCOC)C(=O)c1nccnc1N +CC(C)N(C(=O)CSc1ncnc2ccccc12)C(C)C +CC(c1nc(C(C)(C)C)no1)N1CCc2[nH]nc(C(F)(F)F)c2C1 +CCC(C)n1ncc(C(=O)NCc2ccc3c(c2)OCO3)c1C1CC1 +C=CCOc1ccc(C(=O)NCc2cccnc2)cc1 +Cc1ccccc1OCCn1ncc(Cl)c(Cl)c1=O +COCCN(C)C(=O)c1csc(-c2ncccn2)n1 +CCc1cccc(OCC(=O)NCc2ccco2)c1 +N#CCc1noc(COc2ccc(Cl)cc2Cl)n1 +COc1ccc(OC)c(CN(C)C(=O)Nc2ccccc2)c1 +Cc1nc2ncnn2c(C)c1CCC(=O)Nc1cccc2c1CCCC2 +COc1cccc(Cn2cc(NC(=O)C3CC3c3ccccc3)cn2)c1 +O=S(=O)(NCc1cc2ccccn2n1)c1ccc(F)c(Cl)c1 +CC(=O)Nc1cccc(C(=O)N(CC(C)C)CC(C)C)c1 +CCOC(=O)C1=C(C)Nc2nnnn2C1c1ccccc1 +O=C(NCc1ccncc1)Nc1ccccc1Br +CCc1nc(C2CCCN2C(=O)C2CSc3ccccc3O2)no1 +c1cc(OCc2nc3ccccc3s2)cc(-n2cnnn2)c1 +CS(=O)(=O)N1CCC2(CCCN(C(=O)c3cnccn3)C2)CC1 +CN(C(=O)CSc1nncs1)c1ccccc1 +COc1ccc(OC)c(C(C#N)Cc2cccc(C#N)c2)c1 +CCC(NC(=O)CCNc1c(C)nc2cnccn12)c1cccs1 +CCOc1ccc(F)c(C(=O)Nc2ccc3c(c2)CC(=O)N3)c1F +CCc1ccsc1C(=O)NCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +Cc1cc(C(=O)NC2CCCCC2)ccc1NC(=O)c1ccnnc1 +CCCn1nccc1NC(=O)CNC(=O)c1ccc(F)cc1F +CCOC(C)C(=O)N(CCC(N)=O)c1ccc(F)cc1 +CC(C)CCCNC(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1ccccc1C1(CNC(=O)NCC(=O)NCc2ccco2)CC1 +COCC(=O)N1CCCC1c1cc(Nc2cnccn2)nc(C)n1 +CN(C(=O)CSc1nc(N)cc(=O)[nH]1)c1ccccc1 +Cc1cc(C)n2ncc(-c3noc(C4CC(=O)N(C)C4)n3)c2n1 +CCOc1ccc2nc(SCCCO)[nH]c2c1 +COC(=O)c1ccc(NC(=O)C2CCN(C(C)=O)CC2)cc1 +CCCCNC(=O)NCC1CCN(c2ccccc2)C1 +Cc1cccc(N(C)S(=O)(=O)c2ccc3c(c2)oc(=O)n3C)c1 +Nc1n[nH]c2ncnc(N3CCc4ccccc4C3)c12 +Cc1ccc2cc(C(=O)Nc3cc(Cl)ccn3)[nH]c2c1 +Cc1cc(CN(C)C(=O)C2CCN(S(N)(=O)=O)CC2)no1 +CN1CCN(CC(=O)N2Cc3ccccc3C2)C1=O +CC(C)C(NC(=O)Nc1ccccc1)C(=O)N1CCCCC1 +CC(=O)NCCNC(=O)c1sc2cccc(C)c2c1Cl +c1cc(NCC2CCOCC2)cc(-n2cnnn2)c1 +CCCC(=O)N1CCCC1C(=O)OCCc1ccccc1 +Cc1cc(NC(=O)COc2ccc(Cl)cc2)[nH]n1 +COc1ccc(CNC(=O)c2c[nH]c3cc(Cl)ccc3c2=O)cc1 +CCC(=O)NCc1nc2ccccc2n1Cc1ccc(OC)cc1 +Cc1ccc(C(C#N)CCC(=O)NC(C)(C)C)c(C)c1 +Cc1onc(-c2ccccc2)c1C(=O)NCc1ccco1 +CCCCNc1nnc(-c2cccn(C(C)CC)c2=O)s1 +CC1CN(C(=O)Nc2c(F)cccc2F)CC(C)O1 +c1ccc2c(c1)nc(NCCCn1ccnc1)c1nccn12 +CN(C)c1ccc(NC(=O)c2cccc(Cl)c2)nc1 +CC(C)Oc1cccc(CNC(=O)NC2(CO)CCCC2)c1 +Cc1noc(CCNC(=O)c2ccc(C(C)C)cc2)n1 +CCNC(=O)CN(C)C(=O)c1cc(C)c(C)s1 +Cn1cc(C(C)(C)NC(=O)CNC(=O)NCc2ccc(F)cc2)cn1 +Cc1cc(C)c(C(=O)NCCSc2nccn2C)c(=O)[nH]1 +CCOC1CCN(C(=O)NC(C)c2cc(C)cc(C)c2)CC1 +Cc1ccc(CNC(=O)CSc2nc(C)c(C)c(=O)[nH]2)cc1 +CCOc1cc2ccccc2cc1C(=O)N1CC(O)C1 +Cc1csc(NC(=O)C2CC(=O)N(c3ccccc3)C2)n1 +CC(=O)Nc1cccc(COc2cc(F)cc(F)c2C(C)=O)c1 +CC(=O)Nc1ccc(NC(=O)NCc2cccc(C#N)c2)cc1 +CC(CC(=O)Nc1cccc2c1CCCC2)n1cccn1 +O=C(Nc1cc(-c2ccccc2F)no1)c1cscn1 +Cc1ccc(NC(=O)COC(=O)c2ccc[nH]c2=O)cc1F +CCCn1cc(C(=O)N(C)Cc2nc(-c3ccccn3)no2)c(C)n1 +COc1cccc(C2CC(=O)Nc3c2c(=O)n(C)c(=O)n3C)c1 +COc1cc(OC)c(NS(=O)(=O)c2ccccc2)cc1Cl +CCCCn1nc(C(=O)NC(C)C(C)CC)ccc1=O +CNS(=O)(=O)Cc1ccc(CNC(=O)c2ccc(OC)cc2)cc1 +Cc1noc(N)c1C(=O)OCc1cccc2cccnc12 +Cc1cc(C(=O)CCC(=O)N2CCCC2c2ccc[nH]2)c(C)s1 +CCOc1ccc(C(C)=O)cc1COn1nnc2ccccc21 +CCN(C(=O)c1ccnc(OC2CCC2)c1)c1ccc(F)cc1 +CCOC(=O)c1nc(-c2ccc(Br)cc2)no1 +CN(CC12CC3CC(CC(C3)C1)C2)C(=O)C1CCCN(C(N)=O)C1 +CN1C(=O)CC(NCc2cnn(C)c2)C1c1ccc(Cl)cc1 +O=C(NCc1nnc2n1CCCC2)C1CCOc2ccccc2C1 +CCCC(=O)Nc1cccc(CNC(=O)Nc2ccccn2)c1 +COc1ccc(S(=O)(=O)Nc2cccc(O)c2)cc1 +CC=CCC(=O)Nc1cccc(C(=O)Nc2c(C)cccc2C)c1 +Cn1cc(NC(=O)CNC(=O)c2c[nH]c3ccccc3c2=O)cn1 +Cc1nn(C)c(C(N)=O)c1NC(=O)c1cc2ccc(Cl)cc2n1C +O=C(c1cccc(OCC(F)F)n1)N1CCC2(CCOC2)C1 +Cc1c(C(N)=O)nnn1-c1ccc2c(c1)OCC(=O)N2C +Cc1ccc(C(=O)N2CCC3(CCC(=O)N(CCO)C3)CC2)cc1C +COc1ccccc1C(C#N)NCCN1CCOCC1 +N#Cc1ccccc1COc1cccc(C(=O)N2CCNC(=O)C2)c1 +Cc1n[nH]cc1CNC(=O)CCNC(=O)c1ccco1 +O=C(NCCOc1ccccc1)N1CCOCC1 +Cc1ccc(-c2cnn(CC(=O)Nc3ccc(C)cc3C)c(=O)n2)cc1 +Cn1c(C(F)(F)F)nn(CCNC(=O)c2cccnc2)c1=O +Cc1cc(NC(=O)Cc2csc(NC(=O)c3ccoc3C)n2)no1 +Cn1c(=O)c2[nH]c(-c3ccncc3)nc2n(C)c1=O +Nc1c(Cl)cc(NS(=O)(=O)c2ccccc2)cc1Cl +COc1ccnc(NC(=O)c2cc(C)n(-c3ccccc3)n2)c1 +Cn1ccnc1C(NC(=O)c1n[nH]c(N)c1-c1ccccc1)C1CC1 +CC(=O)NC(C(C)C)C1NCCc2c(F)ccc(F)c21 +COc1cc(N2CC3OCCC3C(C(=O)N3CCCC3)C2)ncn1 +Cc1ccccc1C1CC1C(=O)N1CCN(c2nccs2)CC1 +CCCn1nc(-c2cc(F)ccc2OC)cc(C#N)c1=O +COc1ncc(NC(=O)Nc2cccc(F)c2C)cn1 +CC(NC(=O)c1ccc(-c2cncnc2)nc1)c1ccccc1 +N#Cc1ccsc1NC(=O)Cn1cnc2cc(F)ccc2c1=O +CC1(C)C(=O)N(CCCO)c2cc(N)ccc2S1(=O)=O +CCC(Oc1cc(C)ccc1C)C(=O)NCC1CCCO1 +N#Cc1ccccc1COc1cccc(C(=O)Nc2ccncc2)c1 +Cc1nc(SCc2ccc(C(=O)N(C)C)cc2)n(CC(C)C)c1C +Cc1cc(C)cc(NC(=O)c2cc3c(=O)n4ccccc4nc3n2C)c1 +COCC(C)NC(=O)c1cc(OC)c(OC)c(OC)c1 +O=C(CCc1ccco1)NCC1(c2ccccc2Cl)CCOCC1 +Cc1nc(OCC(=O)NC2CC2)c2c(-c3ccc(F)cc3)noc2n1 +CCOc1ccc(NC(=O)c2cc(OC)c3c(c2)OCCO3)cc1 +Fc1ccc(NCc2ccncc2)c(OCC2CC2)c1 +O=C(NCc1cccnc1)NCc1ccnc(OCc2ccccc2)c1 +Cc1c(C)n(CCO)c2ncn3nc(Cc4ccccc4)nc3c12 +Cc1ccc(-c2ncco2)cc1NC(=O)c1[nH]nc2c1CCCC2 +CN(Cc1cccs1)C(=O)COc1cccc2c1OC(C)(C)C2 +CC1c2ccsc2CCN1Cc1nc(C2CC2)no1 +O=C(OCCCn1c(=O)[nH]c2ccccc21)c1cccc(F)c1 +Cc1cccc2c(CC(=O)Nc3nnc(C(C)C)s3)c[nH]c12 +CCC(=O)NCC(=O)NCCOc1ccc2c(c1)CCC2 +O=C(c1ccsc1)N1CCc2noc(-c3ccccc3)c2C1 +Nc1cc2c(cc1Sc1nncs1)NC(=O)C2 +Nc1nc2n(n1)C(c1cc(Cl)cc(Cl)c1)CCC2 +Cc1noc(CCC(=O)Nc2ncc(Cc3cccc(F)c3)s2)n1 +COc1ccccc1C(C#N)NC(=O)c1cccs1 +COc1c(Cl)cc(C(=O)c2cccc(N)c2)c(O)c1OC +CC1CCCC(NC(=O)CNC(=O)C2CCCC2)C1C +COCCC(NC(=O)NCC(C)(C)O)c1ccc(Cl)cc1 +O=C(C1CCCc2[nH]ncc21)N1CC=C(c2ccc(O)cc2)CC1 +CC(C)n1nccc1NC(=O)N1CCc2sccc2C1 +Cc1cc(N(C)C(=O)c2ccnnc2)ccc1Br +Cc1cc(C)n2nc(C)c(C(=O)Oc3ccc4cn[nH]c4c3)c2n1 +O=C(COC(=O)Cn1cnc2ccccc21)NC1CCCC1 +CCCOC1CCCN(C(=O)NCc2cnn(C)c2)C1 +Cc1csc(NC(=O)c2cc(C3CC3)nc3onc(C)c23)n1 +CCCCN(C)C(=O)CC1OC(=O)c2ccccc21 +CCc1nc(C2CCCN2C(=O)CC2OCCc3ccsc32)no1 +CCCC(C)N(C)c1nc2c(s1)C(=O)CCC2 +CC(=O)c1cc(CC(=O)NCc2ccc(F)cc2)cs1 +CN(CCC#N)C(=O)Nc1ccc(C#N)c(C(F)(F)F)c1 +CCCCOC(=O)C(C)N1CCOCC1C1CC1 +Cc1cc(C)n(C2CCN(C(=O)c3cccc(-n4cccn4)c3)C2)n1 +CC(C)Oc1ccc(CNS(=O)(=O)N(C)C2CCCCC2)cn1 +CNC(=O)NCC(=O)N1CC(c2ccc(F)cc2)CC1C +COc1cccc(C2CC(=O)c3cc(F)cc(N)c3O2)c1 +COc1ccccc1-c1cc(C(=O)NCCN2CCOCC2)n(C)n1 +Cc1n[nH]c(C)c1NC(=O)C1CC(=O)N(C2CC2)C1 +Cc1ccccc1OC(C)C(=O)Nc1nc(C)c(C)s1 +Cc1nnc(SC(C)C(=O)NC2(C#N)CCCCC2)s1 +Cc1csc(C(NC(=O)NCCCc2c(C)noc2C)C2CC2)n1 +CC1CC(NC2CCc3nc(C(C)C)nn3C2)C(=O)O1 +Cc1ccccc1CNc1ccc2scnc2c1N +O=C1CCc2onc(-c3ccccc3Br)c21 +CCOc1ccc(Cl)c2c1CCNC2c1ccnnc1 +CC(=O)N1CCN(CCC(=O)N2CCNCC2)CC1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)CCNC(=O)c1ccco1 +C=CCCC(=O)Nc1cc(C#N)ccc1OC(F)F +COc1cc(C)ccc1OCC(=O)NCC(O)c1ccco1 +CC(=O)NC1CCN(c2ccccc2C(=O)N2CCC(C)CC2)CC1 +CC(NC(=O)c1ccco1)C(=O)N1CCCc2ccccc21 +O=C(Nc1nc(-c2ccccc2)ns1)N1CCC(F)CC1 +CN(C)c1cccc(C(=O)Nc2ccc(-c3csnn3)cc2)c1 +Cc1oc(-c2ccsc2)nc1COc1ccc(-n2cncn2)cc1 +Cc1ccc(C(=O)OCC(=O)Nc2cccc(C#N)c2)c(C)c1 +Cn1nc2n(c1=O)CCN(CCCOCCc1ccccc1)C2 +COC(=O)c1cccc(NC(=O)NCCc2ccccn2)c1 +C=CCNS(=O)(=O)c1ccc(NC(=O)C2CCCC2)cc1 +CCN(CC1CC1)C(=O)Nc1cc(S(=O)(=O)NC)ccc1C +COc1ccc(CCNC(=O)c2ccc3cc[nH]c3n2)cc1 +Cn1c(=O)n(CC(=O)NCc2ccccc2F)c2cccnc21 +O=C(c1ccc(CO)cc1)N1CC(c2ccncc2)C1 +Cc1c(O)cccc1C(=O)N1CCOC(c2ccc(Cl)cc2)C1 +CCN(CC1CCOC1)C(=O)c1cccnc1OCC(F)(F)F +CCn1c(SCCCO)nc2sc3c(c2c1=O)CCCC3 +CCCc1ccc(C(=O)CSc2nc(N)c(C#N)cc2C#N)cc1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)COc2ccccc2)c1 +CCC(Cc1ccc(C)cc1)NC(=O)c1cnn(-c2ccncc2)c1C +CCc1nnc2ccc(C(=O)NC(CC)CO)cn12 +Cc1cc(NC(=O)C2COc3ccc(F)cc3C2)n(C)n1 +CC(C)N(CCO)C(=O)c1cc(F)cc(Br)c1 +O=C(NCCc1csc(-c2ccccn2)n1)c1cccc(F)c1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)c1cccc(-c2ccoc2)c1 +Cc1cccc(S(=O)(=O)NCc2cccc(Cl)c2)c1 +CN(CC1CC1)C(=O)NCc1ccccc1S(=O)(=O)N(C)C +NC(=O)CN1C(=O)C=C(c2cccs2)Nc2ccccc21 +COc1ccc(C(=O)N(C)C(C#N)c2ccncc2)cc1 +CC(=O)Nc1ccc(NC(=O)c2nnn(-c3ccc(C)cc3)c2C)cc1 +COc1ccc(CCNC(=O)Nc2c[nH]c3ccccc23)cc1OC +CCOC1CN(C(=O)c2ccco2)C2CCCOC12 +O=C(NCCc1ccccn1)c1cccc(OCC(F)F)n1 +O=C(NCC1CCOC1)Nc1ccc2c(c1)OCO2 +Cc1cc2sc(NC(=O)NC(C)(C)CO)nc2s1 +CCc1cc(N)cc(C)c1NC(=O)Cc1ccccc1 +COc1cccc(NCC(=O)Nc2cccc(C(C)=O)c2)c1 +Cc1cc(C)n(-c2ccc(NCc3nsc(N(C)C)n3)cc2F)n1 +Cc1oc(C(C)C)cc1C(=O)N1CCNCC1C(=O)NC1CC1 +O=C(Nc1ccccc1)N1CCn2c1nc1ccccc12 +CCOC(=O)Cc1csc(NC(=O)c2ccco2)n1 +COc1cc(NC2CCN(C(=O)c3ccoc3)CC2)cc(OC)c1 +CC(C)C(NS(C)(=O)=O)c1nc(-c2cccnc2)no1 +CCCCCNC(=O)NCc1ccc(OC)nc1 +O=C(NCC1CN2CCCCC2CO1)Nc1cc(F)ccc1F +COC(=O)c1cn(S(=O)(=O)c2ccccc2)c2ccccc12 +COc1c(-c2cnn(C)c(=O)c2CC#N)ccc(C)c1C +COc1cc(C)sc1C(=O)N(C)CC(=O)Nc1cc(C)on1 +CC(NC(=O)CCc1cnn(C)c1)C(=O)N1CCCCC1 +CCN(Cc1cccs1)C(=O)Cn1c(C)csc1=O +Nc1ccc(S(=O)(=O)NC2CCCCC2)cn1 +CCc1cc(=O)oc2cc(OC(C)C(=O)NCCCO)ccc12 +CCCCN(CC(N)=O)C(=O)Cc1ccc(C)cc1 +Cc1ccc(CNC(=O)NCC(=O)NCCc2ccccn2)cc1 +Cc1c(NC(=O)c2ccc3c(c2)OCO3)c(C(=O)N(C)C)nn1C +CCOc1ccc(C(=O)N(CC(=O)N(C)C)CC(F)(F)F)cc1C +COc1ccc(NC(=O)Cn2c(=O)oc3ccccc32)cc1C +O=c1nc(SCc2ccccc2F)c2c(n1CCCO)CCCC2 +O=C(COC(=O)CCC1CCCC1)Nc1ccc2c(c1)OCCO2 +O=c1c2sccc2ncn1CC(O)c1ccccc1F +CCOC(=O)CNC(=O)c1cccc(OC(C)C)c1 +Cc1cc(F)cc2c(=O)c(C(=O)NCc3csc(=O)[nH]3)c[nH]c12 +C=CCN(C)C(=O)c1nc(CCc2ccccc2)n(-c2ccccc2)n1 +O=C(CCn1cnc2sccc2c1=O)NCC1CCOC1 +Cn1cc(NC(=O)NC(CC2CCOC2)c2ccccc2)ccc1=O +CSc1cccc(NC(=O)c2cnn(-c3ccc(F)cc3)c2)c1 +O=C(NCc1noc(-c2ccsc2)n1)Nc1nncs1 +CCN(C(=O)Cn1c(C2CCCO2)nc2ccccc21)c1ccccc1 +O=C(Nc1ccccc1)C1CCCN(c2cc(=O)n3ccccc3n2)C1 +Cc1nn(C(C)CC(=O)n2cnc3ccccc32)c(C)c1Cl +Cc1nn(-c2ccccc2)c(C)c1NC(=O)C1CCC(=O)NC1 +Cc1ccc(OCC(=O)NCC#Cc2ccc(N(C)C)cc2)cc1 +CS(=O)(=O)c1ccccc1C(=O)Nc1cccc2cn[nH]c12 +Cc1ccc(F)c(NC(=O)N2CCCCC2c2nc[nH]n2)c1 +CC(C)c1cccc(-c2ccc(C(=O)NC3CCN(C(N)=O)C3)o2)c1 +CSc1nccnc1CN(C)C1CCN(C(=O)OC(C)(C)C)C1 +Cc1cc(CN(Cc2cccc(F)c2)Cc2cc(C)on2)no1 +CC(C)(C)OC(=O)NC1CCN(C(=O)n2ccnc2)CC1 +Cc1ccc(CNc2cccc(S(=O)(=O)NC3CC3)c2)cc1C +Cc1c(NC(=O)CNC(=O)C2CC2)c(C(=O)N(C)C)nn1C +CCc1noc(CC)c1CC(=O)Nc1nc2ccccc2s1 +COc1cc(C)nn2c(C(=O)NC3CCCCC3)nnc12 +CCOC(=O)c1c(CNC(C)(C)c2nccs2)oc2ccccc12 +Cc1cccc(C(=O)NC2CC3C(=O)N4CCCC4C(=O)N3C2)c1 +CNc1c(F)cccc1C(=O)NCC1CCCCO1 +CCc1cc(NC(=O)Cc2cccc(C(=O)OC)c2)nc(C)n1 +O=c1c(=Cc2cccc(O)c2)sc2nc3ccccc3n12 +OCCN(CCO)c1nc(-c2ccccc2)nc2c1oc1ccccc12 +CC(=O)N(C)c1ccc(NC(=O)NCC=Cc2ccccc2)cc1 +COC(=O)c1cc(N)ccc1N(CCC#N)C1CC1 +Cc1cc(C)n(-c2ccc(CSc3ncn[nH]3)cc2)n1 +c1csc(C(CNCc2cccc3c2OCO3)N2CCOCC2)c1 +O=C(C1CC=CCC1)N1CCC(Oc2cnccn2)CC1 +O=C(OCC1CCCO1)c1cccc2c1OCCO2 +Cc1c(C)n(Cc2ccccc2)c2ncnc(N3CCCC3)c12 +COc1ccc(NC(=O)NC2CCN(C(=O)OC(C)(C)C)C2)cc1 +CCOC(=O)CN(C)C(=O)c1ccc(F)cc1F +Cc1csc2cc(C(=O)N3CCC(C(N)=O)CC3)cnc12 +Cc1cc(Oc2cccnc2)nc(C2CCN(c3ncccn3)CC2)n1 +Cc1cccc(NC(=O)c2cc3scnc3[nH]2)c1 +COCc1ccc(C(=O)N2CC(NC(C)=O)C(c3ccc(C)o3)C2)o1 +CC(C)(C)c1nc(CNC(=O)C2(Cc3ccccc3)CCC2)no1 +Cc1cc(CSc2nnc(C3CC3)n2C2CC2)no1 +C=CCN(c1ccccc1)S(=O)(=O)c1ccsc1C(=O)OC +Fc1cccc2ncnc(N3CCN(c4ccc(Cl)cn4)CC3)c12 +O=C1NCCC(CCCCCc2nnc(-c3ccco3)o2)N1 +CCC(C(=O)Nc1ccc(Cl)cc1)N1CCCC1=O +O=C(NCc1ccncc1)c1cccc(OC(F)F)c1 +COC(=O)c1cc(C#N)c(=O)n(CC(O)CN2CCOCC2)c1 +CC(c1cccnc1)N(C)C(=O)CSc1nnnn1C1CC1 +CC(C)OCc1cccc(CNC(=O)c2ccc3ncccc3n2)c1 +Cc1nccn1-c1ccc(NC(=O)c2cnn(-c3ccccc3)n2)cn1 +O=C(c1cc(Br)c[nH]1)N1CCCCC1c1nc[nH]n1 +Cn1cc(C(=O)Oc2ccc(F)cc2F)c(C(F)(F)F)n1 +CC(C)C1CCCN(C(=O)C2CCCN2C(=O)C2CC2)CC1 +Cn1cc(C(=O)OCc2ccc(C(N)=O)cc2)cn1 +Cc1ccccc1C1CN(Cc2ccno2)C(C)CO1 +CC(C)CC(=O)N(Cc1nccn1Cc1cccc(F)c1)C(C)C +COCc1cc(NCc2cccnc2Oc2ccc(C)nc2)ncn1 +O=c1c(=Cc2ccccc2)sc2nc(-c3cccnc3)nn12 +N#Cc1ccccc1CN1C(=O)C(=O)c2cc(Br)ccc21 +CCCC(=O)N1CCC(C(=O)NCc2cnc(C)s2)CC1 +CC(NC(=O)c1ccccc1)C(=O)NCCc1cccc(F)c1 +Brc1cc(N2CCOCC2)c2[nH]cnc2c1 +CCOc1ccc(C(C)NC(=O)CCc2c(C)nc(C)[nH]c2=O)cc1 +O=C(COc1ccc(F)cc1)NCCc1csc(N2CCCC2)n1 +COC(=O)c1ccccc1SCC(=O)N1CCc2ccccc21 +CCCNC(=O)CNC(=O)c1c(C)nn(-c2ccccc2)c1C +COC(=O)N1CCC(NC(=O)NCc2cscn2)CC1 +CN(C)S(=O)(=O)N1CCC(Cc2cccc3cccnc23)C1 +Nc1nonc1-c1nnc(C2Cc3ccccc3N2)o1 +CC1CN(CC(=O)N(C)Cc2cccs2)CC(c2ccccc2)O1 +CCCCC1CCC(CNS(=O)(=O)N(C)C)CC1 +COCC(=O)Nc1ccc(-c2cn3nc(OC)ccc3n2)cc1 +CC(O)(CNC(=O)c1cnc2n(c1=O)CCS2)c1ccc(F)cc1 +COc1ccc2c(c1)CCCC2CC(=O)NCc1cn2ccccc2n1 +CCOC(=O)CCNC(=O)Nc1cccc(C(C)=O)c1 +COCC(C)Nc1nc2nonc2nc1NCc1ccccc1 +Nc1ccc(-c2csc(CC(=O)N3CCCCCC3)n2)cc1 +O=S(=O)(NCCC(O)C1CC1)c1ccc(C(F)(F)F)cc1 +COc1ccc(Cl)cc1CNCC(c1ccco1)N(C)C +Cc1nc(=O)[nH]c(C)c1CCC(=O)N1CCC2(CC1)OCCCC2O +CCC(=O)N1CCCN(C(=O)c2cccc3c2ccn3C)CC1 +COc1cccc2cc(C(=O)Nc3sc(C)c(C)c3C#N)oc12 +COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12 +CCC1COCCN1C(=O)Cc1ccc(O)c(Cl)c1 +Cn1nc(C(=O)N2CCCC2)c(=O)c2cc(F)ccc21 +O=C(NCCS(=O)(=O)NCC1CCC1)Nc1c(F)cccc1F +Cc1noc(C)c1C(=O)OCC(=O)N1CCC(C(N)=O)CC1 +Nc1ccc2c(n1)N(Cc1ccccc1F)C(=O)CO2 +Cc1nc(CN2CCN(c3ncnc4c3cnn4C)CC2)cs1 +c1ccc2c(c1)nnn2Cc1nnc2sc(-c3ccncc3)nn12 +CCCc1nn(Cc2nnc(C3CC3)n2C2CC2)c(=O)o1 +CC(C)CCS(=O)(=O)NCCc1c[nH]c2ccc(F)cc12 +CNC(=O)c1cccc(CCNC(=O)N(C)C(C)c2ccccc2)c1 +CCCCCc1nc2sc3c(c2c(=O)n1N)CCC3 +CSc1cccc(NC(=O)NCCc2nc(C(C)C)no2)c1 +COc1nn(C)c2nc(C)c(CCC(=O)NCC3CC3C)c(C)c12 +Cc1ccc(N(C)Cc2nnnn2C2CC2)c(C)c1 +CCC(=O)c1ccc2c(c1)N(CCCO)C(=O)C(C(C)C)O2 +CCOc1cccc(NCc2ccc(O)cc2F)c1 +CCOc1cccc2c1CCNC2c1ncccn1 +O=C(c1c[nH]c2ccc(Br)cc12)N1CCCC1 +CNC(=O)C(C)Sc1nnnn1-c1ccc(O)cc1 +CCc1cnc(N2CCC3(CCCN3C(=O)N(C)C)CC2)nc1 +NC(=O)c1ccc(NC(=O)c2[nH]ncc2Br)cc1Cl +CC(C(=O)Nc1cccc2oc(C(F)(F)F)nc12)n1cccn1 +Cc1ccc(CC(=O)Nc2ccc(-n3cncn3)cc2)cn1 +O=C1CC2(CCN(C(=O)c3ccncc3)C2)Oc2ccccc21 +O=C(c1cccc2ncccc12)N1CCOC(c2ccccc2F)C1 +c1ccc2oc(N3CCc4sccc4C3)nc2c1 +CCOC(=O)CCC(C)NC(=O)c1cnc2ccc(C)cn12 +CN(Cc1ccncc1)S(=O)(=O)c1cn[nH]c1 +CSc1ncccc1C(=O)NC(C)(C)c1ccccc1 +Cc1ccc(NC(=O)N(C)CC2CC2)cc1S(C)(=O)=O +CC(NC(=O)COc1cccc(-n2ccnc2)c1)c1cccs1 +Fc1cccc(Cl)c1Cn1nnc(-c2ccncc2)n1 +Cc1cc(CC2COCC2NC(=O)CN2CCCC2=O)on1 +CCCC1CN(C(=O)COCCc2ccccc2)CCO1 +CC(C)Cn1c(N)c(-c2csc(-c3ccoc3)n2)c(=O)n(C)c1=O +CCCc1ccc2c(c1)C(c1cnoc1C)NCC2 +CC(=O)C(C)n1c(C(C)NC(=O)c2cccnc2)nc2ccccc21 +COC(=O)CCS(=O)(=O)Nc1c(C)n[nH]c1C +CCn1nc(C)c2ccn(CC(=O)NC(C)c3ccccc3)c(=O)c21 +CCc1cn[nH]c1C1CCN(C(=O)c2cnn3ccn(C)c23)CC1 +Cn1c(=O)c2[nH]c(C3CCC(O)C3)nc2n(C)c1=O +COC(=O)c1cccc(CCNC(=O)N(C)C(C)CO)c1 +CCNc1ccc(Cl)cc1NC(=O)c1cc(NC(C)=O)ccc1F +Cc1n[nH]c2ncc(NC(=O)C(C3CC3)C3CC3)cc12 +O=C(Cc1ccc(O)cc1)Nc1ccc(F)cc1F +Cc1nc(C)c(C(=O)N2CCCC2C(=O)Nc2nccs2)s1 +Cc1cnc(CNC(=O)C2CC(=O)N(c3ccc(O)cc3)C2)cn1 +Cc1cc(C)c(C(=O)NCCC(O)c2cccs2)c(C)c1 +O=C(OC(c1ccccc1)c1ccncc1)c1cc(C2CC2)on1 +COc1cccc(C2NCCc3c(N)cc(F)cc32)n1 +Cc1ccc(CN(C)C(=O)CSc2nccn2C)o1 +CN1C(=O)C2(CCCC2)NC1c1cc2ccccc2o1 +Cc1nc(C)c(C(C)N(C)Cc2cccc(O)c2)s1 +COc1ccccc1CNC(C)C(=O)Nc1ccccc1 +CCc1nnc(NC(=O)c2nc(SC(C)C)ncc2Cl)s1 +CC1CCCN(c2ncc3c(n2)CN(c2cnn(C(C)C)c2)C3=O)C1 +CN(CC(N)=O)C(=O)c1cc(-c2ccccc2Cl)[nH]n1 +CNC(=O)c1cc(Cl)ccc1NCC(=O)N1CCCCC1 +Cc1cc(NC(=O)c2cc(-c3ccccc3)no2)n(C)n1 +Cc1nc(C)c(CCC(=O)Nc2ccccc2OCC(C)C)c(=O)[nH]1 +CCc1onc(C)c1NC(=O)c1cc(C)n(CC)c1C +N#Cc1ccc(CNC(=O)CCCc2cc(F)ccc2F)cc1 +Cn1cc(-c2ncnc3c2CCN(Cc2ccsc2)CC3)cn1 +CC(O)(CNC(=O)Nc1ccc(F)cc1)C1CC1 +O=C(NCCc1ccccc1)c1cccc2nccnc12 +COc1ccc(NC(C)=O)cc1NC(=O)C(C)Nc1ccc(F)cc1 +CCOc1ncccc1CNC(=O)Nc1cccc(C)c1C +Cc1c(CNCCc2cccs2)cc(C#N)n1C +COc1cc(CNC(=O)c2ccc(F)cc2)cc(OC)c1OC +CCc1n[nH]c(SCC(=O)NC(CC)c2ccc(Cl)cc2)n1 +COc1ccc(C(Nc2ccc(C)cc2)C(N)=O)cc1Br +COc1cc(=O)[nH]c(SC(C)C(=O)NCc2ccccc2)n1 +CCOCCOC(=O)C1COc2ccc(F)cc2C1 +O=C(COc1ccc2ccc(=O)oc2c1)NCCCO +O=C(NCCC12CC3CC(CC(C3)C1)C2)c1cnccn1 +O=C(NC1CC1)c1cn(C2CCN(C(=O)c3ccncc3)CC2)nn1 +O=C(Cn1cnc2sccc2c1=O)Nc1nc2ccccc2[nH]1 +CC1CCCN(C(=O)c2ccc(-c3cccnc3)nc2)C1 +CCCc1cc(C(=O)N2CCN(C(=O)OCC)CC2)sc1C +Cc1cc(C(=O)CSc2nncn2C)c(C)n1Cc1cccs1 +Cc1ccnc(NC(=O)CN2CCN(c3ccc(F)cc3)C2=O)c1 +CSc1nc(C(=O)NC(C2CC2)C2CC2)c2ccccn12 +CCN(C(=O)c1sc(-c2ncccn2)nc1C)C1CCCC1 +CSc1cccc(NC(=O)CCC(=O)Nc2nccs2)c1 +COc1ccc2oc(-c3csc(NC(=O)C4CC4)n3)cc2c1 +CSc1nnc(CSc2n[nH]c(=O)n2C2CC2)s1 +CCCCc1cnc2c(c1SC(C)C)c(=O)n(C)c(=O)n2C +COc1cc(C)ccc1OCC(=O)Nc1ccnc2ccnn12 +COc1ccc(-c2nc(C)c(CCO)s2)cc1F +COc1ccc(C(C)NCCN2CCOCC2)cc1F +COc1ccccc1Oc1ccc(NC(=O)NCc2ccncc2)cc1 +CC(=O)N(C)Cc1cccc(NC(=O)NC(C)c2ccc(C)o2)c1 +CCC(CO)NC(=O)NCC1CN2CCCCC2CO1 +Cc1cc(C)c(NC(=O)c2cc(S(C)(=O)=O)ccc2C)c(C)n1 +CCC(C)c1ccccc1NC(=O)CSc1ncccn1 +CCCc1nc2cccnc2n1C1CCN(C(=O)C2CCC2)C1 +CCCCOC(=O)Cn1nnc(-c2cccs2)n1 +CC(CO)NS(=O)(=O)N(C)Cc1ccccc1 +CCn1c(C)cc(C(=O)Nc2ccc3c(c2)COC3)c1C +COCC1CCCN1C(=O)CN1C(=O)CCc2ccccc21 +CCC(C)(C)NC(=O)c1cn(-c2ccc(Cl)cc2)nn1 +O=C1CCC(COC(=O)C2CC2c2ccccc2F)N1 +C=CCN1C(=O)C2(NC(=O)c3cccc(C)c3N2)c2ccccc21 +Cc1ccc(S(=O)(=O)N(C)C)cc1C(=O)N1CCOC(C)C1 +COc1cccc(N2CC3(CCN(C(=O)C4CC4)C3)CC2=O)c1 +CCN(C(=O)CNC(=O)OC)c1cccc(F)c1 +Cc1n[nH]c(C)c1CCC(=O)NC1CCN(c2ccccc2)CC1 +COCCN(C)C(=O)c1cc2cc(N)ccc2s1 +O=C(c1cc(S(=O)(=O)N2CCCC2)c[nH]1)N1CCc2ccccc21 +Cc1noc2nc(C(C)C)cc(C(=O)NCCC(=O)N(C)C)c12 +O=C(Cc1ccc[nH]1)N(Cc1ccccc1F)C1CC1 +Cn1c(C(=O)NC2CCCC2)nc2cc(C#N)ccc21 +CCCCS(=O)(=O)NC(c1ccc2c(c1)OCCO2)C1CC1 +CC(O)c1nc2cccc(F)c2n1Cc1cccc(N)c1 +Cc1ccsc1CN(Cc1cc(F)cc(F)c1)CC(C)O +CC(CC(=O)NCc1ccoc1)c1ccc(F)cc1 +CN(C)c1c(Cl)cccc1NC(=O)c1cc(C2CC2)[nH]n1 +C#Cc1cccc(NC(=O)N(CC)Cc2ccc3c(c2)OCO3)c1 +Cc1nc(-n2cccc2)sc1C(=O)NCCn1ncccc1=O +COc1ccc2c(=O)n(CSc3nccn3C)cnc2c1 +CCOC(=O)c1nnc(-c2cccs2)nc1N1CC(C)OC(C)C1 +O=C(NCCNc1cnccn1)c1ccc(O)cc1 +COc1ccc(CN2CCOC(C#N)C2)c(OC(F)F)c1 +Cc1ccn(C(=O)Cc2cccc3ccccc23)n1 +COc1ccccc1Oc1ccc(NC(=O)Nc2cn[nH]c2)cc1 +COCCCCNC(=O)N1CCN(c2ncnc3c2cnn3C)CC1 +Cc1cc(CN2CCN(CC(=O)NCC3CCCCC3)CC2)on1 +O=C(CC1=CCCCC1)N1CCC(O)(C(F)(F)F)CC1 +COc1cc(C)c(C(=O)Nc2ccc(Cl)c(C#N)c2)cc1OC +CN(CC1CC1)C(=O)CSc1nncc2ccccc12 +CN(C)C(=O)COc1cc(C(=O)Nc2ccccc2)nn1C +CCc1noc(CC)c1CNC(=O)CNS(C)(=O)=O +Cc1cccc(CNC(=O)CNC(=O)CC(C)(C)C)c1 +COc1cccc(OC)c1-c1nccn1Cc1ccc(O)cc1 +Cc1ccc(C(=O)Nc2ccncc2)cc1NC(=O)c1ccco1 +C=CCNC(=O)C1CCN(S(=O)(=O)N2CCCCC2)CC1 +CC1Sc2ccc(-c3cc(N)ncn3)cc2NC1=O +COCc1ccc(C(=O)Nc2ccc(OC)cc2OC)cc1 +Cc1nn(Cc2ccccc2)c(=O)n1-c1cccc(Cl)c1 +Cc1cc(=O)[nH]c(SCc2nc(-c3ccc4c(c3)OCO4)no2)n1 +O=C(Nc1ccc(F)c(F)c1)c1cnn(-c2ccccc2)c1 +N#CCc1ccc(NC(=O)COc2ccc(F)cc2)cc1 +CCOCCCNC(=O)c1c(F)cc(Br)cc1F +C1=C(CCNc2nc3ccccc3nc2N2CCOCC2)CCOC1 +CC(C)c1cc(C2CCCN2C(=O)c2cnn3c2CCCC3)no1 +CCOC(=O)c1oc(N)c(C(=O)NCc2ccccc2)c1C +CC(C)n1c(=O)n(CC(=O)N2CCc3ccccc32)c2cccnc21 +O=C(c1c[nH]c2cccc(F)c12)N1CCc2ccccc21 +COC(=O)CCC(=O)NC(C)c1c(C)noc1C +N#Cc1ccc(NCCCOc2cccc3cccnc23)nc1 +CC1CCC(NC(=O)C2CC(=O)N(C3CCCCCC3)C2)CC1 +COCCCOCC(=O)Nc1cc(N)ccc1Cl +NC(=O)c1ccc(Nc2ncnc3sc4c(c23)CCC4)cc1 +CCC1(CC)Oc2cccc(N)c2N(CC(=O)NC)C1=O +Cc1nc(NC(=O)CCC2CCCCC2)sc1C(=O)N(C)C +O=C(COC(=O)c1cccc(F)c1)NCc1cc(F)cc(F)c1 +COC(=O)c1c(C(N)=O)c(C)n(NC(=O)Nc2ccccc2)c1C +CC(C)NC(=O)CNC(=O)c1cc2ccc(Cl)cc2n1C +O=C(CCC(=O)c1ccc2c(c1)OCCCO2)Nc1ccccc1F +CC(NC(=O)c1ccc(C(F)(F)F)cc1)C1CCCO1 +CCN(CC(=O)NC(C)(C)C)C(=O)CNC(=O)OC +COc1ccc(OC)c(S(=O)(=O)N2CCCC(C(N)=O)C2)c1 +CC(=O)NCCOc1ccc2cc(Br)ccc2c1 +O=c1[nH]nc(CCc2ccccc2O)n1Cc1ccco1 +COCCCNC(=O)NCC(O)c1ccc(C)cc1 +O=C(Cn1cnnn1)NCCn1c(=O)oc2ccccc21 +CC(C)CC(=O)NCC#CCN(C)Cc1ccccc1 +CCC(CC)N(CCO)S(=O)(=O)c1ccc(C)cc1 +Nc1cccc(OCCNC(=O)CC2CCCC2)c1 +CC(Nc1nc(CO)nc2ccccc12)c1ccsc1 +O=C(Nn1cnc2ccccc2c1=O)c1cc(F)c(F)cc1Cl +CN1C(=O)COc2ccc(-c3cc(C#N)n[nH]3)cc21 +Cc1cc(F)ccc1NC(=O)c1ccnc(OC2CCC2)c1 +CCCC(=O)N1CCN(c2nc3c(c(=O)[nH]c(=O)n3C)n2CC)CC1 +CCCOc1cn(-c2ccccc2)nc1C(=O)NCc1cccnc1 +O=C(Nc1cccnc1)C1CCN(C(=O)Nc2ccccc2)CC1 +O=C(COc1ccccc1F)Nc1nc2c(s1)CCCC2 +CCC(=O)Nc1ccc(C(=O)n2nnc3ccccc32)cc1 +Cc1n[nH]c(C)c1NC(=O)Nc1cccc(-c2ncco2)c1 +CC(Nc1ccccc1S(N)(=O)=O)c1cccs1 +CC(C)N(C)c1ccc(NC(=O)C2CCCO2)cc1F +Cc1cc(C(=O)NC(c2cccc(F)c2)c2nccn2C)c(C)o1 +Cc1nc2cc(C(=O)NCCN3CCc4ccccc43)ccc2[nH]1 +O=S(=O)(Cc1ccc(F)cc1)NCc1ccc[nH]1 +CCOC(=O)Cn1cnc2sc(C(=O)OC)c(C)c2c1=O +C=CCOC(=O)CCc1nc(-c2ccc(F)c(C)c2)no1 +COc1cccc(-n2c(=O)c(C#N)cc3c(=O)n4ccccc4nc32)c1 +O=C(Cn1ccc2c(Cl)cccc21)NCc1ccncc1 +COCc1ccsc1C(=O)Nc1sc(C)cc1C(N)=O +COc1ccc(F)cc1NC(=O)C(C)Oc1ccc(C#N)cc1 +Cc1ccccc1C(=O)NCCCCNc1ccc(N)cn1 +O=c1cc(C2CCC2)ncn1Cc1nc(-c2ccco2)no1 +Cc1ccccc1NC(=O)C1CC(=O)Nc2ccccc21 +CC1(C(=O)NCc2ccc(Cl)cc2)Sc2ccccc2NC1=O +COC(=O)CN(C(=O)c1cccc(N(C)C)c1)C1CCCC1 +CNS(=O)(=O)c1cccc(CNC(=O)c2ccc(COC)o2)c1 +COc1ccc(NC(=O)c2cnn(C)c2)cc1S(=O)(=O)N(C)C +COC(=O)c1[nH]c(C)cc1NS(=O)(=O)c1cn(C)cn1 +Cc1cc(C)c2c(n1)sc1c(N(CCO)CCO)ncnc12 +COc1ccc(-c2c(NCc3ccco3)c(=O)c2=O)cc1 +COc1ccccc1OCc1nc2ccc(OC(C)=O)cc2c(=O)o1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCC2(C)COC2)n1 +Cn1nnc(C2CCN(C(=O)OC(C)(C)C)C2)n1 +Cc1cc(F)ccc1S(=O)(=O)NCC(O)(c1ccco1)C1CC1 +COC(=O)NCC(=O)Nc1cccc(C(N)=O)c1C +NC(=O)CCCNC(=O)c1c[nH]c2ccccc2c1=O +Cc1sc(C(=O)N2CCC(C(N)=O)C2)cc1-c1ccc(F)cc1 +COC(=O)C(C)Nc1ncc(Br)c2c(N)cccc12 +CC1=NC(=O)C(CCC(=O)NCc2ccc(C)cc2)C(C)=N1 +CC(C)(C)C(NC(=O)CCCc1cc(F)ccc1F)C(N)=O +COC(=O)N1CCC2(O)CCCCC2C1c1ccc(OC)cc1OC +CCCCS(=O)(=O)N(C)c1ccccc1C(=O)OC +CC(=O)Nc1ccc(NC(=O)C(C)Sc2ccc(Cl)cc2)cc1 +Cc1n[nH]cc1NC(=O)C1Oc2ccccc2OC1C +COc1ccccc1NS(=O)(=O)c1ccc2oc(N)nc2c1 +O=C(NCc1ccco1)c1ccc(Cl)cc1O +O=C(NCc1ccccc1F)Nc1ccc(-n2cnnn2)cc1 +CC(=O)N1CCc2cc(NC3CCOCC3)ccc21 +O=C(Cc1csc(NC(=O)c2ccco2)n1)Nc1nccs1 +CC1(C)CCCN1C(=O)CNC(=O)c1cccs1 +Cn1cc(CNc2ccc(NS(C)(=O)=O)cc2)c(C(C)(C)C)n1 +Cc1ccc2ncc(C(=O)N3CC(C)OCC3C)n2c1 +CCc1cccc(NC(=O)CSc2ncccn2)c1 +CC(C)(C)CN(CCC#N)C(=O)c1noc2c1CCCC2 +CC1CCC(C(N)=O)CN1C(=O)C1Cc2cc(Cl)ccc2O1 +O=C(Nc1ccc(Cl)cc1)c1cn2c3c(cccc3c1=O)CC2 +Cc1ccc(C(=O)NCCC2CNc3ccccc32)cc1O +O=C(NC1CCCC1CO)c1ccc(CCC(F)(F)F)cc1 +Cc1csc(Nc2ccc(NC(=O)Cc3cc(C)on3)cc2)n1 +COc1ccc(CN2Cc3cc(N)ccc3S2(=O)=O)cc1 +OC(CNCc1ccc(-n2ccnc2)cc1)c1ccc(F)cc1 +CCc1cccc(NC(=O)CC(C)n2ccnc2)c1 +Cc1c(C(=O)Nc2ccncc2)sc2cccc(F)c12 +O=C(Nc1cc(Cl)cc(Cl)c1)c1cscn1 +CC(=O)OCc1coc(C(C)=O)c1COC(C)=O +CC(C)S(=O)(=O)N1CCCC(c2nnc(C(F)(F)F)o2)C1 +Cc1ccccc1N1CC(C(=O)N2CCC(C)CC2)CC1=O +CCS(=O)(=O)c1cccc(NCc2noc(CC(C)C)n2)c1 +CS(=O)c1ccc(CNc2ccc(-n3ccnc3)c(Cl)c2)cc1 +CC(C)c1nc2cc3c(cc2n1C(C)C)OCCO3 +CN(C)C(=O)C1CCCN(C(=O)c2cccnc2OCC(F)F)C1 +CN(C)C(=O)C(C)(C)NC(=O)c1ccc(OCC(F)F)nc1 +CC(NC(=O)NCc1ncn(C)n1)C(=O)Nc1ccccc1 +CCc1cc(=O)oc2cc(OCC(=O)NCCCO)c(Cl)cc12 +COc1cccc(OC)c1Cc1nc(-c2ccc(C#N)cn2)no1 +CCc1noc(CC)c1CNC(=O)CNC(=O)c1ccc(C#N)cc1 +O=C(c1cnc(C2CCCO2)s1)N1CCN(c2ccccc2)CC1 +CCN(Cc1ccc2c(c1)OCO2)c1ncc(S(N)(=O)=O)s1 +Cc1cccn2c(NC(=O)c3ccccn3)c(-c3ccccc3)nc12 +CCOC(=O)c1cnc(C)c(C(=O)OC)c1C(F)(F)F +CCc1cc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)sc1C +NS(=O)(=O)c1ccc(C(=O)NCc2cccc(Cl)c2)cc1 +Cn1cnnc1S(=O)(=O)CC(=O)N1CCCc2ccccc21 +Cc1cc(C)nc(SCC(=O)NCC2CCCO2)n1 +COc1ccc(-c2cc(=O)c3cnccc3o2)cc1 +COc1ccccc1C(=O)CNS(=O)(=O)c1cccs1 +COc1ccc(NC(=O)C#Cc2ccccc2)cc1S(N)(=O)=O +NC(=O)C1CN(Cc2cnn(-c3ccc(F)cc3)c2)CCO1 +Cc1cc(NC(=O)C(C)Sc2nc(-c3cccs3)n[nH]2)no1 +Cc1c(C(=O)Nc2ccccn2)nnn1-c1ccc2c(c1)OCCO2 +CCc1n[nH]c(SCC(=O)N(C)c2nc3ccccc3s2)n1 +CC(C)NC(=O)NCc1ccccc1NS(=O)(=O)c1ccccc1 +O=C(Nc1cccc2c1CCCC2)c1ccc(-n2ccnc2)cc1 +CCCn1nc(C(=O)NC(Cc2ccccc2)C2CC2)ccc1=O +C=CCn1c(N)nnc1SCCCc1ccccc1 +CC(=O)NC(CC(=O)Oc1ccc(Cl)cc1C)c1ccc(C)cc1 +Cc1csc(CCNS(=O)(=O)Cc2ccc(F)c(Cl)c2)n1 +Cc1nc2ccccc2n1CCCNC(=O)CC1C=CCC1 +CNS(=O)(=O)c1ccc(OC(C)C)c(Cl)c1 +Cc1nnc2n1CCN(C(=O)Cc1csc(-c3ccccc3)n1)C2 +Cc1cc(Cl)ccc1OC(=O)c1cn(CC(=O)N(C)C)nn1 +CN(C)C(=O)CNC(=O)NCCCSc1ccccc1 +CCc1ccc(-c2n[nH]c(SCC(=O)Nc3cc(C)on3)n2)cc1 +COc1ccc(OC)c(C(=O)N(C)CCC(F)(F)F)c1 +CCOc1ccccc1N1CCN(C(=O)c2ccc(C#N)cc2)CC1 +CC1(COC(=O)Cc2ccc(F)cc2F)COC1 +O=C(c1csnn1)N1CCC(c2nc3cc(Cl)ccc3o2)CC1 +COc1ccc(S(=O)(=O)N2CCCn3ncnc32)c(C)c1C +CCOC(=O)c1ccc(NCC(=O)Nc2ccc3c(c2)OCO3)cc1 +N#CCCNC(=O)CNc1cc(Cl)cc(Cl)c1 +N#CCc1cccc(C(=O)Nc2ccc(O)cc2)c1 +CC1(C)C2OCCC2C1OC(=O)c1ccc(-n2ccnc2)cc1 +CCOc1ccc(CNC(=O)N2CCc3ccccc32)cc1OC +COc1ccccc1C(C)NC(=O)Cn1nc(C)nc1C +COc1ccc(Cl)cc1NC(=O)NCCCN1CCOCC1 +Cc1c(C(=O)NCC(=O)N2CCCCC2)nc2c(Cl)cccn12 +CC(C)CN1CCOC(COC(=O)c2cc(C(C)(C)C)n[nH]2)C1 +Cn1nc(C(=O)Nc2ccccc2SC(F)F)ccc1=O +O=C(CNc1ncnc2ccccc12)NCC(F)(F)F +Cc1cc(NC(=O)c2cc3occc3n2Cc2ccccc2)no1 +NC(=O)C(NC(=O)c1cnn(Cc2ccccc2)c1)c1ccccc1 +COc1cc(N2CC(C(=O)NC3CC3)CC3OCCC32)ncn1 +c1ccc(OCC2CC2)c(NCc2cscn2)c1 +O=C(c1ccco1)N1CCC(c2nnc(-c3ccoc3)o2)CC1 +CCN(Cc1ccccc1)C(=O)CNc1ccccc1F +COc1ccc(C#CCNC(=O)Cc2c[nH]c3ccccc23)cc1 +CCCc1cc(C(=O)Nc2ccccc2OC)n(C)n1 +CCc1noc(CC)c1CNC(=O)NCc1ccnc(C)n1 +COc1ccsc1C(=O)NCc1cccc(-c2n[nH]c(C)n2)c1 +O=C(Nc1ccc(-n2cncn2)c(C(F)(F)F)c1)C1CCCO1 +NC(C(=O)NCc1cncnc1)c1cccc(F)c1 +COc1cccc(CNC(=O)c2cn(C)n3cccc3c2=O)c1 +O=C(C(c1cccs1)C1CC1)N1CCNCC1 +O=C(Nc1nnc(C2CCC2)s1)c1ccc(Br)cc1 +CC(C)Cc1ccc(S(=O)(=O)N(C)C(C)c2ccccn2)cc1 +CCn1nnc2c(=O)n(CC(=O)N3CCCCCC3)cnc21 +CC(C)Oc1cccc(C(C)NC(=O)c2cc(C(N)=O)cs2)c1 +CCn1c(=O)c(C(=O)Nc2cccc(F)c2)nc2ccccc21 +CC(=O)Nc1cccc(C(=O)N2CCOCC2C2CC2)c1 +COC(C)(C)c1noc(C(C)NC(=O)C(C)(C)C)n1 +N#Cc1c(F)cccc1NCCNC(=O)C1CC(=O)N(CC2CC2)C1 +CC(C)(C)NC(=O)CNC(=O)c1ccc(Br)cc1Cl +Cc1cccc2c1CCN2C(=O)c1ccnc(OC2CCC2)c1 +O=C(c1ccc(-n2ccnc2)nc1)N1CCC(c2ccccc2)CC1 +Cc1noc(C)c1C(C)NC(=O)c1cnc2[nH]nc(C)c2c1 +CC(C)CNC(=O)COc1ccc(C(N)=O)cc1 +O=C(Nc1nc(C(=O)NCc2ccco2)co1)c1ccccc1 +OCc1ccccc1OCCOc1ccc2ncccc2c1 +O=C(NC(c1ccccc1)c1ccccn1)c1n[nH]c(=O)[nH]1 +CC(=O)c1cccc(NC(=O)Cn2ccc(-c3ccsc3)n2)c1 +C=C(C)Cn1c(CCNC(=O)c2cccnc2)nc2ccccc21 +COC(=O)c1c(C)[nH]c(C(=O)CN(C)Cc2sccc2C)c1C +CCNc1ncnc2c1cnn2-c1ccc(C)c(C)c1 +O=C(CNc1ncc(C(F)(F)F)cc1Cl)N1CCCCC1 +COC(=O)c1cc(N2CC(O)C2)c2cc(Br)ccc2n1 +COc1nn(C)cc1C(=O)NCC#Cc1ccccc1N(C)C +CC(C)Cc1nc2c(N)cc(Br)cc2[nH]1 +N#CC1(C(=O)NCC(=O)Nc2ccc(-n3cncn3)cc2)CCCC1 +CC(C)(C)CCNC(=O)CSc1ccc(O)cc1 +CC(C)(C)OC(=O)N1CCCCC1COCCO +Cc1ccc(C(=O)NC(Cc2ccccc2)c2ccccc2)cn1 +Cc1ccccc1C(=O)Nc1ccc(N)cc1Cl +COC(=O)c1ccc(OS(=O)(=O)c2ccc(F)cc2)cc1 +O=C(Nc1ccccc1N1CCOC1=O)c1n[nH]c2ccccc12 +O=C(CSc1nnc(NC2CCCCC2)s1)N1CCCC1 +Cc1nonc1CC(=O)NCCn1nnn(-c2ccccc2)c1=O +COC(C)C(=O)Nc1cccc(NC(=O)NCC2(C)CCCC2)c1 +O=C(CCNC(=O)c1cccs1)NCCc1ccc(F)cc1 +CC(Oc1ccc[nH]c1=NS(C)(=O)=O)c1ccccc1 +CC1CCCN(S(=O)(=O)c2cccc(S(C)(=O)=O)c2)C1 +O=C(NCCc1ccco1)c1ccc(Br)cc1F +CN(C)S(=O)(=O)c1ccc(C(=O)NCC2(O)CCCC2)cc1 +C=CCN(CC=C)C(=O)C(C)Sc1nc2sccc2c(=O)n1C +CC(C)=CCN(Cc1nc2ccccc2c(=O)[nH]1)C(C)C +Cc1ccc(C(=O)N(C)c2ccc(Br)cc2F)cn1 +O=C1C2CCC(CN(c3nccs3)C2)N1Cc1cscn1 +COCCCNC(=O)C1CSc2nc(C(C)(C)C)cc(=O)n2C1 +CC(Cc1cccs1)n1ccc2c1CCCC2O +COCCOc1ccc(NC(=O)C(C)(C)C)cc1 +O=C(Cn1ncc(Cl)c(Cl)c1=O)NCC1CCCO1 +O=C(NCC1CN2CCCCC2CO1)N1CCCC1 +Cc1c(Cl)ccc2c(=O)c(C(=O)NCc3ccccc3)c[nH]c12 +C#CCNC(=O)NC(C)c1ccc(-c2cncnc2)cc1 +CC(=O)Nc1cc(NC(=O)NCCC2CC3CCC2C3)ccc1F +COc1cc(F)ccc1N1CCN(Cc2n[nH]c(=O)[nH]2)CC1 +Cc1ccc(-n2cc(-c3cn(Cc4n[nH]c(=O)[nH]4)nn3)cn2)cc1C +CCOc1ncccc1C(=O)Nc1ccccc1C(=O)NC1CC1 +NC(=O)c1ccccc1OCC(=O)NC1CCOc2ccccc21 +O=S(=O)(Oc1ccc(Cl)c2cccnc12)c1c[nH]cn1 +CC(C)(C)C(=O)N1CCC(C(=O)OCCCc2cccnc2)CC1 +COCC(NC(=O)c1cn(-c2ccc(F)cc2)nn1)C(N)=O +Cc1cc(CNC(=O)NCCc2c[nH]c3c(C)cccc23)no1 +CC(=O)N1CCN(C(=O)c2sc3cccc(F)c3c2C)CC1 +CCc1noc(CSc2nc(C3CCCC3)n[nH]2)n1 +O=C(NCc1ccnc(OC2CCC2)c1)c1noc2c1CCCC2 +Nn1c(SCC(=O)N2CCCC2)nnc(-c2ccccc2)c1=O +Cc1ncsc1C(=O)N(Cc1ccccc1)C(CO)C1CC1 +Cn1nc(Oc2ccc(-c3ccccc3)cc2)c(=O)n(C)c1=O +Cc1nc(-c2cccc(CNC(=O)C(C)Oc3ccccc3)c2)n[nH]1 +COCCN(C)C(=O)C1CCCN(S(=O)(=O)c2ccccc2)C1 +COC(C)(C(=O)Nc1cccc(Cn2cncn2)c1)c1ccccc1 +CN(C)c1ccc(NC(=O)c2ccc(OCC(N)=O)cc2)nc1 +CC(C)Oc1ccc(NC(=O)c2scnc2C2CC2)cc1C#N +CCn1nc(-c2ccc(OC)c(C)c2)cc(CO)c1=O +COC(=O)CN1CCN(C(=O)c2cc(C)nn2C)CC1 +CC(C)c1ccc(OCCC(=O)N2CCC(C(=O)N(C)C)CC2)cc1 +CCCS(=O)(=O)NCc1ccc(Cn2ccccc2=O)cc1 +Cc1cc(C)c(C#N)c(SCC(=O)NC(C)C(C)C)n1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)N(C)C)CC2)cc1Cl +CN(C)c1ncc(C(=O)N2CCn3cc(C(F)(F)F)nc3C2)cn1 +Cc1cc(CN2CCN(C(=O)c3ccc(C)o3)CC2)on1 +Cc1ccc(-c2noc(Cn3cnc(C4CCC4)cc3=O)n2)cc1F +Cn1cc(C(=O)CSc2nnnn2-c2ccccc2)c2ccccc21 +COc1ccc(C(=O)NCc2csc3ccccc23)cc1 +CCC(C)CN(C)C(=O)NCc1cccc(CN2CCCC2=O)c1 +O=C(Nc1ccc2ncccc2c1)c1cc(-c2cccs2)n[nH]1 +COc1ccc(NC(=O)Cn2cnc3cc(C)c(C)cc32)c(OC)c1 +Cc1cc(CN(CCC#N)Cc2ccccn2)ccc1-n1cncn1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1 +Cc1cc(C(=O)NCCCCN(C)c2ccccc2)n(C)n1 +CCOC(=O)c1ccc(-n2ccc3c(c(C)nc4ncnn43)c2=O)cc1 +Cc1c(C(=O)Nc2cnn(C)c2)sc2nc[nH]c(=O)c12 +CCC(Sc1nc(N)cc(=O)[nH]1)C(=O)Nc1ccc(O)cc1 +COC(=O)c1cc(F)ncc1NC(=O)OC(C)(C)C +CC(=O)NC(C)C(=O)OCCCn1c(C)nc2ccccc21 +O=C(Nc1ccc(Br)cn1)c1sccc1OC(F)F +Cc1nnc(SCCNc2ncnc3cccc(F)c23)s1 +CN(C(=O)Cn1cnnn1)C1CCN(c2ccccc2)C1=O +CCc1nnc(-c2cn(CC(=O)N3CCCC3)c3ccccc23)o1 +CCC(=O)c1ccc2c(c1)N(CC(=O)N(C)CCC#N)C(=O)CO2 +Cc1ccc(NC(=O)c2noc3c2CC(C)CC3)nc1 +O=C(CCc1cccs1)NCc1ccc2c(c1)OCO2 +CCOc1cccc(CC(CO)CNC(C)=O)c1 +Cn1cc(-c2ncnc3c2CCN(c2ncccn2)CC3)cn1 +CN(CCC(=O)c1ccc(F)c(N)c1)c1ccccc1 +O=C(CCc1ccc2c(c1)OCCCO2)NCCOc1cccnc1 +Cc1cccc2c(=O)n(CCC(=O)N3c4ccccc4CC3C)cnc12 +OCCn1c(-c2ccccc2)nc2cc(F)c(F)cc21 +CC(=O)Nc1cc(C(=O)C(C#N)c2nc(C)cc(C)n2)ccc1C +Cc1c(NC(=O)NCCO)cccc1OC1CCCC1 +OCC1CN(c2ccc(Cl)cc2)C(c2ccco2)O1 +COc1cc(CCC(=O)Nc2c(C)cc(C)nc2C)cc(OC)c1 +CCCOc1cccc(C(=O)NCC(=O)OC)c1 +CC(=O)NC1CCCN(C(=O)Nc2cccc(Br)c2)C1 +O=S(=O)(Cc1ccccc1F)NC(CCO)c1cccs1 +Cc1ccc(NC(=O)Cn2ccccc2=O)c(Br)c1 +CC(C)n1nc(-c2nc(-c3ccc(F)cc3)no2)ccc1=O +N#Cc1sc2nc(-c3ccncc3)cc(C(F)(F)F)c2c1N +COc1ccc(C(=O)NC(c2ccccc2)c2cccnc2)cc1OC +Cc1c(Br)cccc1S(=O)(=O)N(C)CC(C)(C)O +Cc1cccc(N(C)CC(=O)Nc2ccc(S(C)(=O)=O)cc2)c1C +Cc1ccccc1-c1ncc(C(=O)N2CCCCCC2)c(N)n1 +N#CCc1cccc(C(=O)NCCN2CCOCC2)c1 +Cc1ccc2nc(COC(=O)C3CC(=O)N(C(C)C)C3)cc(=O)n2c1 +CCC(C)NC(=O)c1ccc(NC(=O)c2cccs2)cc1 +COc1ccccc1COc1cccc(C(C)O)c1 +CCS(=O)c1ccccc1C(=O)NCc1ccccc1OC +COc1ccc(CNc2ccc(F)c(F)c2)cc1OC +O=S(=O)(NCc1ccccc1)c1cc(-c2ccno2)cs1 +Cn1c(C2CCN(C(=O)c3cccnc3)CC2)nc2ccccc21 +CCC(CC)n1nc(C)c2nc(C3CCOC(C)(C)C3)[nH]c21 +Clc1cccc(N2CCN(Cc3nc(-c4ccco4)no3)CC2)c1 +Cc1cccc(C(C)C)c1NC(=O)NCCc1nc(C(C)C)no1 +CCCc1nc(CN2CCN(c3ncnc4sccc34)CC2)no1 +Cc1cnn(CC2CCCN2C(=O)C2Cc3cc(Cl)ccc3O2)c1 +CC(NC(N)=O)C(=O)NCc1cccc(OCC(F)(F)F)c1 +CC(C)N(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +CC(=O)N1CCN(C(=O)CSc2ncnc3ccccc23)CC1 +COC(=O)C1(N(C)C(=O)c2cccc3c2ccn3C)CCCCC1 +CCn1cnnc1CNC(=O)COc1ccc2ccc(=O)oc2c1 +Cc1csc(SCc2nc3sc4c(c3c(=O)[nH]2)CCC4)n1 +CC(C)OCCOC(=O)Cn1ncc(=O)c2ccccc21 +COc1cc(O)ccc1C(N)C(=O)NCC(C)C +O=S(=O)(N1CCOCC1)N1CCN(c2ccccc2F)CC1 +COC(CNC(=O)Nc1ccccc1C(F)(F)F)c1ccsc1 +O=C(CCC1CCCC1)N(CCO)C1CCCC1 +N#Cc1c(C2CCCO2)nn(-c2ccncc2)c1N +CC(C)CN1C(=O)C(C)(C)COc2ccc(N)cc21 +COc1ccc(N(C(C)C(=O)N2CCCC2)S(C)(=O)=O)cc1 +CCCCc1ccc(NC(=O)CCn2ccccc2=O)cc1 +NC(=O)Cn1c(CO)cnc1SCc1cccc(F)c1 +CCCS(=O)(=O)N1CCCN(Cc2noc(C(C)(C)C)n2)CC1 +O=C(NCCCC(=O)N1CCN(Cc2ccccn2)CC1)C1CC1 +COc1cccc(COC(=O)CCc2cnn(C)c2)c1 +CC(C)(C)c1nnc(CNc2cccc(OCC(F)(F)F)c2)o1 +N#Cc1ccc(NCc2ccc(-n3ccnc3)cc2)c(C(F)(F)F)c1 +Nc1nc(-c2cccnc2)nc(-c2cccnc2)n1 +O=C(c1ccccc1F)N1CCN(CC(O)C(F)(F)F)CC1 +CCn1cc(C)c(-c2ccccc2Cl)c(C#N)c1=O +CC(NC(=O)c1ccc(O)cc1F)C(=O)Nc1ccccc1 +O=C(Nc1ccc2nc(-c3ccc(F)cc3)[nH]c2c1)C1CCCO1 +Nc1ccc2c(c1)CCN2C(=O)c1ccc(F)cc1Cl +CN(C(=O)C(O)(c1ccccc1)c1ccccc1)c1ccccc1 +CCOC(=O)c1sc2ncnc(NC3CC3)c2c1C +CCc1cc(=O)[nH]c(-c2ccc(C(F)(F)F)cc2)n1 +Cc1cc2onc(-c3cccc(N)c3)c2cc1Cl +O=C(Cn1nnc2ccccc2c1=O)NC1CC2CC1C1CCCC21 +COC(=O)C(C)CNc1ccc(S(N)(=O)=O)cc1 +CC(C)(C)C(=O)CNC(=O)c1cccc2cc[nH]c12 +Cc1cc(C)cc(NC(=O)c2cn3cc(N)ccc3n2)c1 +CCNc1nc2sc3c(c2c(=O)n1C(C)C)CCCC3 +CC(=O)Nc1cccc(NC(=O)Nc2ccc(C)cc2)c1 +CC(C)N(C)C(=O)COc1ccccc1Br +CCn1ncc(-c2ccc3c(c2)OCO3)c(N)c1=O +CCc1nnc(NC(=O)c2cc(NC(=O)c3ccco3)n(C)n2)s1 +COc1ccccc1NC(=O)COc1ccccc1O +COc1cc(NCc2cnn(-c3ccccc3)c2)ccc1NC(C)=O +CN(Cc1cccnc1)S(=O)(=O)c1cccc(C(N)=O)c1 +Cc1ccc(-c2cc(C(=O)NC(C)C(=O)NC(C)C)no2)cc1 +CN(Cc1ccc(F)cc1)C(=O)COc1ccccc1O +CCOc1ccc(OCc2noc(C3CC3)n2)cc1 +CSc1cccc(NC(=O)Nc2ccc(C(=O)NC3CC3)cc2)c1 +CCCc1cc(=O)n(CC)c(NC2CCCCC2)n1 +COc1ccc(CCC(=O)Nc2cccc(-c3nnnn3C)c2)cc1 +CC(Cc1ccco1)NC(=O)c1ccc2c(c1)OCCO2 +CN(C)C(=O)c1cccc(C2CCCN(S(C)(=O)=O)C2)n1 +COc1ccccc1NC(=O)C(C)Oc1cccc(C#N)c1 +CC(=O)Nc1cc(NC(=O)CCC2CCCC2)ccc1Cl +N#Cc1ccc(C(=O)Nc2nc(-c3c[nH]c4ccccc34)cs2)cc1 +Cc1ccc(C(=O)CCC(=O)N(C)Cc2cccc(C#N)c2)cc1 +CC(CNc1ccccc1)NC(=O)c1ccncc1Cl +CN(C)S(=O)(=O)NCC1(c2cccc(F)c2)CCOCC1 +c1coc(CNCC2OCCc3cn(CC4CC4)nc32)c1 +Cn1nc(-c2ccc3c(c2)NC(=O)CO3)c2ccccc2c1=O +Cc1cc(C)n(Cc2cccc(C(=O)N(C)C(C3CC3)C3CC3)c2)n1 +Cc1ccc(SCCC(=O)N(C)c2cccc(C#N)c2)cc1 +CSc1ccccc1NC(=O)c1cnc2n(c1=O)CCS2 +COc1cc(CNC(=O)C(C)OCC(C)C)ccn1 +CC(=O)Nc1ccc(F)c(C(=O)N2CCc3cc(F)ccc3C2)c1 +COc1cc(CNC(=O)C(C)Oc2ccc(Cl)c(C)c2)ccn1 +Cc1cc(N)c(NS(=O)(=O)N(C)C(C)C)cc1C +COC(=O)C1CCCN1C(=O)c1ccc(OCc2cscn2)cc1 +CN(CCc1ccccn1)C(=O)NCC(C)(C)N1CCOCC1 +C#Cc1cccc(NC(C)c2ccc(S(C)(=O)=O)cc2)c1 +C=CCn1c(C)nnc1SC(C)c1ccc(C(=O)OC)o1 +CCCNC(=O)c1ccc(NC(=O)C2CCCO2)cc1 +CCOC(=O)Cc1ncc2ccc(Br)cc2n1 +Cc1ncccc1C(=O)Nc1cc(Cl)ccc1C(=O)N1CCCC1 +CNc1nc(CNC(=O)Nc2ccc(OC(C)(C)C)cc2)cs1 +COCCCNC(=O)N1CC=C(c2c[nH]c3ccc(OC)cc23)CC1 +CCC(=O)c1ccc(OS(=O)(=O)c2cccc(C#N)c2)cc1 +O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)N1CCCC1 +CCNC(=O)C(C)NC(=O)NCc1ccsc1 +CCn1cc(C(=O)Nc2nn(-c3ccccc3Cl)cc2C)cn1 +Cc1ccccc1C(C)NS(=O)(=O)c1cccs1 +O=C(Nc1cccc(CO)c1)c1cccc(Br)c1 +CCCCNC(=O)C1CCN(C(=O)c2csc3c2CCCC3)CC1 +CNC(=O)c1ccc(S(=O)(=O)NC2CCc3cc(F)ccc32)cc1 +Cc1nc(NCc2ccco2)sc1C(=O)Nc1ccc(F)cc1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1ccc(C)nc1C +CCc1noc(CC)c1CNC(=O)c1cnn(C(C)(C)C)c1 +CCCCOc1ccccc1-c1cc(C(=O)NCC)nc(N)n1 +N#Cc1nc2c(C#N)c3sc4ccccc4n3c2nc1C#N +COc1ccccc1OCC#CCNC(=O)c1c[nH]c2ccccc12 +Cc1n[nH]c(SCC(=O)NCc2ccc(-c3ccn[nH]3)cc2)n1 +CCC(=O)NCc1ccccc1-c1cc(N)nc2[nH]ccc12 +CCCNC(=O)C(C)NC(=O)NCc1ccccc1Cl +COCc1ccc(SC(C)C(=O)NC(C)(C)C)cc1 +CCCn1cnc2c1c(=O)n(CC1CC1)c(=O)n2-c1ccc(F)cc1 +Cc1ccc(-n2nc(-c3cnn(C)c3)cc2-c2cnn(C)c2)cc1 +CCc1nnc(C(=O)Nc2ccc(C(=O)N3CCOCC3)cc2)s1 +CCOCc1cccc(NCc2c[nH]nc2-c2cccnc2)c1 +Fc1c(Cl)ccc2c1CCNC2c1ncccn1 +CCC(OC)C(=O)Nc1ccccc1OC1CCCC1 +Cn1ccnc1Cn1c(C(C)(C)C)nc2cc(N)ccc21 +O=C(CCc1nc2ccccc2s1)NCCc1cccs1 +CN(Cc1nccn1C(F)F)C(=O)Cc1c(Cl)cccc1Cl +COc1c(C)cc(Br)cc1C(=O)NCc1cccnc1 +Cc1cc(C)c(C(=O)CCN2CCC(=O)CC2)c(C)c1 +CCCC1CCC(NC(=O)c2cnc3c(c2)c(C)nn3C)CC1 +Nc1cc(N2CCc3[nH]nc(-c4ccccc4F)c3C2)ncn1 +CC(C)C(=O)N1CCCC1C(=O)NCCOc1cccnc1 +CCc1ccc(NC(=O)N2CCC(C(=O)N(C)C(C)C)CC2)cc1 +CC(C)(C)CC(=O)NCCNC(=O)c1cnc2ccoc2c1 +Cc1cc2c(ncn2Cc2ccccc2)c(NS(C)(=O)=O)c1C +CC(C)Oc1ccc(C(=O)N(CCc2cccc(F)c2)C2CC2)cn1 +O=C(NCC(F)(F)F)Nc1ccc(F)c(F)c1F +C=CCN(C(=O)Cc1ccc(C)nc1)c1nc(-c2ccccc2)cs1 +O=C(NCc1ccccn1)c1coc(COc2cccc(F)c2)n1 +CCc1ccsc1CNC(=O)CSc1nc(C)n[nH]1 +CN1C(=O)Cc2cc(C(=O)CN3CCC(=O)CC3)ccc21 +Cc1ccc2[nH]nc(C(=O)N3CCN(Cc4cccnc4)CC3)c2c1 +Cc1ccc(NC(=O)c2cn3c(C)cccc3n2)nc1 +Cc1ccc(-c2nnco2)cc1NC(=O)c1cc(Cl)c[nH]1 +Cc1csc(N(C(=O)c2ccc(Cn3ccnc3)cc2)C2CC2)n1 +CCOC(=O)c1conc1-c1c[nH]c2ccccc12 +CN(C)c1cccc(C(=O)NCC2(N3CCOCC3)CCCCC2)c1 +O=C(c1c[nH]c2ccccc2c1=O)N1CCCC1c1ccc(F)cc1 +CCOC(=O)c1cc2c([nH]c1=O)CC(c1ccc(C)o1)CC2=O +COc1ccc(NC(=O)N(C)C(C)c2cccc(O)c2)cc1F +CS(=O)(=O)NC1CCCN(c2ncccc2F)C1 +Cc1c(Cl)cccc1S(=O)(=O)Nc1cn[nH]c1 +N#Cc1ccc(-c2noc(-c3ccc(N4CCCC4)c(F)c3)n2)nc1 +CNC(=O)c1cccc(NC(=O)NCc2cc(C)nn2C)c1C +Cc1cc(NC(=O)CSc2nc(C(C)C)nc3ccccc23)no1 +CC(OCC1CC1)C(=O)N1CCCC1c1ccc2c(c1)OCO2 +CC(C)(O)C(O)Cc1c2occc2cc2ccc(=O)oc12 +COc1ccccc1NC(=O)COc1ccccc1C(N)=O +CCOc1ccc(NC(=O)COc2ccc(C#N)cc2OC)cc1 +Cc1c(NC(=O)c2ccccn2)cccc1-n1cnnn1 +Cc1cc(C)n(Cc2nnnn2-c2ccccc2)c(=O)c1C#N +Cc1cc(CN2CCOC(Cn3nc(C)nc3C)C2)on1 +Cc1ccc(F)cc1C(=O)OCCc1c(C)n[nH]c1C +CCCN(CC(F)F)C(=O)NCc1cc(=O)[nH]c2ccccc12 +CNC(=O)c1ccccc1NC(=O)c1ccccc1F +COc1ccc(OC)c(C(=O)N2CCCN(C(C)=O)CC2)c1 +COc1ccc(-c2nc3cc(N)ccc3n2C)c(F)c1 +CCOC(C)C(=O)Nc1ccc(OCC2CCOCC2)cc1 +CCOC(=O)c1ccoc1CNc1cccc(-c2ccnc(C)n2)c1 +Cc1cccc2c1NC(=O)C21CC(O)=Nc2[nH]ncc21 +O=C(NCCCO)c1nc2c3c4c(sc3ncn2n1)CCCC4 +COc1ccc(C2CCN(C(=O)Nc3cccnc3)C2)cc1 +COc1ccc(NC(=O)N2CC(C)OC(C)C2)c(OC)c1 +Cn1nnnc1-c1cccc(NCc2nnc(C(C)(C)C)o2)c1 +O=C(CC1CCCc2ccccc21)N1CCCCC(CO)C1 +CNC(=O)NCC(=O)N(Cc1ccc(Cl)cc1)C1CC1 +Cc1ccsc1CN(CCCO)CC(F)(F)F +CC(C)n1nc(CNC(=O)CC#N)c2c1CN(C(N)=O)CC2 +CCCc1nccn1-c1ccc2c(c1)CCCN2C(C)=O +O=C(OCCCc1ccccc1)c1ccnc(-n2cncn2)c1 +Cc1cc(NC(=O)NCCc2nc(C(C)(C)C)cs2)no1 +CCCCS(=O)(=O)Nc1ccc(OC)c(N)c1 +COc1ccc(CCC2=NC(=O)CN2)cc1Br +Cc1[nH]c(-c2nnc(C3CCC3)o2)c(C)c1S(=O)(=O)NC1CC1 +CSc1nc(C)c(CCC(=O)N(C(C)C)C2CCC2)c(C)n1 +CC(Sc1n[nH]c(=O)n1C1CC1)C(=O)NCC(C)c1ccccc1 +CCCNC(=O)CN(CCC)C(=O)c1c(C)nn2cccnc12 +CCOC(=O)C1CCCN(c2ncc(N)cc2Cl)C1 +Cc1cc(=O)c(C(=O)NC2CCCC2)nn1-c1ccccc1F +CC(C)N(C(=O)CNc1cc(CO)ccc1Cl)c1ccccc1 +Cc1ccc(CNC(=O)Cn2cc(C#N)c3ccccc32)cc1 +CN(C)C(=O)COc1cccc(NC(=O)c2ccsc2)c1 +COc1c(C)cnc(COc2cccc(-n3cncn3)c2)c1C +Cc1cc2[nH]c(=O)[nH]c2cc1C(O)c1ccccc1Cl +CS(=O)(=O)c1ccc(Cl)c(C(=O)NC2CCCCCC2)c1 +Cc1nnc(SCC(=O)NCc2cccc(C(F)(F)F)c2)n1N +CCOC(=O)c1cc(-c2ccc(OCC)cc2)[nH]c1N +COC(=O)c1cc(-c2cc(C)cc(N)c2OC)nn1CCO +O=C(COCC1CC1)NC(c1ccccc1)c1ccccn1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCC(c2ccc(O)cc2)CC1 +Cc1cc(Sc2ccccc2)ccc1NC(=O)C1CCC(=O)NC1 +COc1cc(C(=O)NC(C)CCc2ccco2)cc2c1OCCO2 +CC(Cc1ccccc1F)NS(=O)(=O)c1cc(C(N)=O)n(C)c1 +CCCNc1ncnc(Nc2ccc(Cl)cc2)c1N +Cc1cc2ncc3c(n2n1)CC1CCC3N1Cc1ccc(C)o1 +Cc1ccccc1NS(=O)(=O)c1ccc(F)c(F)c1 +O=C(NCCN1CCOCC1)N1CCc2ccc(Cl)cc2C1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1cc(C)no1 +CCOC(=O)COc1cc(-c2nc(C)cs2)ccc1N +CCC(=O)c1ccc(OC(=O)C2CC(=O)Nc3ccccc32)cc1 +CCC1CN(C(C)=O)CCC1NC(C)C(=O)NCC(C)C +Cc1ccc(S(=O)(=O)N(Cc2cccnc2)Cc2ccco2)cc1 +CN(C)C(=O)N1CCN(c2ncnc3ccccc23)CC1 +CCOC(=O)Cc1nc2ccc(Cl)cc2s1 +Cc1noc(C2CN(C(=O)C3COc4ccccc4O3)C2)n1 +O=C(CSc1ccc(F)cc1)N1CCC(Oc2cccnc2)CC1 +N#Cc1ccc(NC(=O)N2CCC(Oc3ncccn3)CC2)cn1 +Cc1ccc(C)c(N2CC(C(=O)Nc3cccc(C)n3)CC2=O)c1 +Cc1csc(CN(C)C(=O)Cc2csc(-c3ccoc3)n2)n1 +O=C(Nc1cnc(-c2ccccc2)nc1)c1csnn1 +CCC(C)(CC)NC(=O)Cc1c(C)nn(CC(C)C)c1C +O=C(COc1ccc(F)cc1)NCCc1ccoc1 +Cc1ccccc1NC(=O)CN1C(=O)COc2ccccc21 +CCOc1ccccc1CNC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1S(C)(=O)=O +COc1cccc(NC(=O)c2ccc(O)c(Cl)c2)c1 +O=C(C(O)c1cc(Cl)cc(Cl)c1)N1CCCC1CO +O=S(=O)(NCc1cccnc1)c1ccc(F)cc1F +COc1ccc(C(=O)NCC#CCOc2cccc3cccnc23)cc1 +Cc1nc(C(C)(C)NC(=O)Cc2c(Cl)cccc2Cl)no1 +O=C1CCCN1c1ccc(CC(=O)N2CCCC2C2CCCC2)cc1 +CNC(=O)C1Cc2ccccc2N1C(=O)Nc1ccc(Cl)cc1 +NC(=O)c1ccc(NC(=O)c2ccncc2F)cn1 +CCCOc1c(Cl)cc(C(=O)N2CCCC(O)C2)cc1OCC +Cc1cccc(C(C(=O)NCCc2cc(=O)[nH]c(C)n2)N(C)C)c1 +Cc1ccc(F)cc1NC(=O)CNC(=O)c1ccccc1Cl +O=C(Nc1cc(Br)ccc1N1CCOCC1)NC1CC1 +COc1ccccc1CN1CCN(C(=O)Cc2ccc[nH]2)CC1 +O=c1[nH]c(-c2ccnc(OCC(F)(F)F)c2)nc2ccsc12 +O=C(c1ccc(Br)cn1)N1CCc2cc(F)ccc2C1 +CC(=O)NCC(CO)Cc1cccc(Cl)c1Cl +O=C(NCc1cccs1)c1cc2n(n1)CCS2 +COc1ncccc1CNC(=O)Nc1ccccn1 +O=C(NCc1ccc(N2CCCC2=O)cc1)C1CCC1 +Cc1cc(C)cc(C(=O)OCC(=O)c2ccc3[nH]c(=O)[nH]c3c2)c1 +O=C(NCCCN1CCOCC1)C1CC(=O)N(Cc2ccccc2)C1 +CC1(C)N=C(CCCCC2=NC(C)(C)C(=O)O2)OC1=O +COCc1cc(NCc2c(C)noc2C)nc(C(C)(C)C)n1 +O=C(Cc1ccc(NC(=O)c2cc3ccccc3[nH]2)cc1)NC1CC1 +O=C(NCC(=O)N1CCc2ccccc21)c1ccccc1Cl +Cc1ncccc1CNc1cnn(-c2ccccc2F)c1 +CCCCN(CC)S(=O)(=O)c1ccc2c(c1)CCN2C(C)=O +CN(CCNS(C)(=O)=O)C(=O)c1ccc(Cl)c(Cl)c1 +Cc1nnc(NC(=O)N2CCC(OCc3ccccc3)CC2)s1 +CC1CCC(C(N)=O)CN1C(=O)c1cnc(C(C)(C)C)s1 +O=C(c1cc2ccccn2c1)N1CCC2(CC1)OCCO2 +CN(Cc1cccs1)C(=O)c1cc(COc2cccc(F)c2)[nH]n1 +COc1ccccc1CN1CCn2nc(C(=O)NC3CC3)cc2C1=O +CCc1ccc(C2COCCN2Cc2c(C)nn(CC)c2C)o1 +CCCOc1ccccc1-c1ccc(C#N)c(=O)[nH]1 +CNC(=O)c1cc(NC(=O)C2CC3CCC2C3)ccc1Cl +COc1ccc(OC)c(-n2cnnc2Cc2ccncc2)c1 +CC(C)Oc1cncc(C(=O)C(C#N)c2nc3ccccc3[nH]2)c1 +Cn1cc(CO)c(-c2ccc(Cl)c(Cl)c2)n1 +O=S(=O)(Cc1cccc(Cl)c1)NCCc1ccoc1 +CN(C)c1ncc(NC(=O)Nc2ccccc2Cl)cn1 +Cc1cc(C)n(CCNC(=O)c2ccc3oc(C)cc3c2)c(=O)n1 +CC(C)Cn1ccc2cc(NC(=O)N(C)CCO)ccc21 +FC(F)(F)c1nn(-c2ccccc2)c2ccncc12 +CC(C)CN(CCO)S(=O)(=O)c1cccs1 +O=C(NCCc1ccsc1)N1CCN(c2ncccn2)CC1 +N#CCc1cccc(C(=O)NCc2nc(-c3ccc(F)cc3)n[nH]2)c1 +Cc1cc(CNC(C)C(=O)NC(C)(C)C)ccc1F +COc1cccc(C(=O)N(CC(F)(F)F)C2CCOCC2)c1OC +CSc1nnc(NC(=O)Nc2ccc(Cl)cc2)s1 +CSc1cccc(NC(=O)Cc2nnc(-c3ccsc3)o2)c1 +CCOC(=O)NC(C(=O)N1CCOCC1)C(C)C +N#CCOc1cccc(CC(=O)Oc2ccc3c(c2)CCC(=O)N3)c1 +CCC(=O)Nc1nonc1-c1ccc(Br)cc1 +Cc1ccc(CN(C)C(=O)c2cccc(S(N)(=O)=O)c2)o1 +CCC(C)NC(=O)N(CCOC)CC1(C)CCOCC1 +COc1ccc(C(O)CNC(=O)C(C)C)cc1Cl +O=C(Nc1ccccc1-n1ccnc1)c1ccc(OCC(F)F)nc1 +O=C(CCc1ccccc1)Nc1n[nH]c(-c2ccco2)n1 +CCc1ccccc1NCc1cc(OC)c(O)c(OC)c1 +COC(=O)c1cc(CNC(=O)C(C)CC2CCCC2)oc1C +CC(C)N(Cc1nc(-c2ccccc2)no1)C(=O)c1cccs1 +Cc1nc2cc(F)ccc2cc1C(=O)N(CCO)Cc1ccccc1 +O=C1CCN(C(=O)c2cc(F)cc(Br)c2)CC1 +COc1ccccc1CNC(=O)c1cccc(C(F)(F)F)c1 +Cc1ccccc1C(=O)NCC#CCOc1ccccc1C(N)=O +CC(=O)Nc1cccc(OC(=O)C=C(C)c2ccccc2F)c1 +O=C(Nc1ccc(Br)cn1)OCc1ccccc1 +O=C(OCc1ccccn1)c1cnc2ccccn2c1=O +CC(CC#N)N(C)C(=O)Nc1cc(-c2ccccc2)on1 +CCN(CC)C(=O)CCC(=O)Nc1nc(C)no1 +COC(CNC(=O)C1CCCC1)c1cccc(F)c1 +CCCCn1nc(C2CCOC2)nc1-c1cnc(NC)nc1 +O=C(Cc1ccc(F)cc1)NCC(C1CCOC1)N1CCOCC1 +CC(C)(C)c1nc2scc(-c3ccccn3)n2c1N +CS(=O)(=O)c1ccc(C(=O)NC2CC2c2cccc(Cl)c2)cc1 +Fc1ccc(CNC(Cn2cncn2)c2ccccc2)cc1 +Cc1nc(C(=O)N2CCCc3cc(F)c(F)cc32)cs1 +Cc1ccc(C2CN(S(C)(=O)=O)CC2NC(=O)COC(C)C)o1 +COc1ccc(C#CCNC(=O)Nc2cc(OC)cc(OC)c2)cc1 +CCOc1cc(NCc2cccc3c2OCO3)ncn1 +N#CCCn1cc(C(=O)COc2ccc(F)cc2F)c2ccccc21 +Cc1ccc(C(=O)NC(C)C(c2ccccc2)N2CCOCC2)s1 +Cc1cc(C)nc(C2CCN(Cc3cnc(N(C)C)nc3)C2)n1 +C#CCN1CCN(C(=O)c2ccc(OC)cc2O)CC1 +CC(NC(=O)NCC1CCCO1)c1ccc(Cl)cc1Cl +Cc1cc(C#N)ccc1C(=O)NCC1CN2CCCCC2CO1 +O=C(NC1CCCC1)c1coc(NC(=O)c2ccco2)n1 +COc1ccc(S(=O)(=O)NCc2ccncc2)c2ccccc12 +Nc1ccccc1-c1nc2cc3ccccc3cc2[nH]c1=O +O=C1CCC(NC(=O)c2ccc(Cl)cc2Cl)CN1 +CCCCn1nc(C(=O)NCc2ccc3c(c2)OCO3)ccc1=O +Cc1cc(C(=O)Nc2ccc(-n3ccnc3C)nc2)on1 +Cc1cc(C(=O)NC(C)c2ccc(Cl)cc2)c(C)o1 +O=C1CCCN1c1ccccc1NCc1cc(=O)n2ccsc2n1 +Cc1nc(C(C)NC(=O)c2cnc(Nc3ccccc3)nc2)n[nH]1 +NC(=O)C1CCCCCC1NC(=O)c1ccnc(OC2CCC2)c1 +Cc1c(-c2ccccc2)nc(-c2ccccn2)n1O +O=C(Nc1ccc(Cl)cn1)c1c(F)c(F)c(F)c(F)c1F +CC1CCN(c2ncnc(NCCCN3CCOCC3)c2N)CC1 +NC(=O)C(Cc1ccc(O)cc1)NC(=O)C1CCOCC1 +Cc1ccc(-c2nc(C(=O)NCC3CCOC3)cs2)o1 +O=C(COC(=O)c1cnccn1)NCCc1ccc(Cl)cc1 +CC(NC(=O)c1ccsc1)c1ccc(F)c(Cl)c1 +Cc1oc2ncn(C)c(=O)c2c1C(=O)NCc1ccccn1 +CC(C)(C)C(=O)NCC(=O)N1CCCC1Cc1ccccc1 +CC(=O)c1ccccc1NC(=O)CNc1c(F)cccc1F +Fc1ccc(C2CC(c3ccccc3)=Nc3ncnn32)cc1 +Cn1cc(-c2nn(-c3nccs3)c3c2CNCC3)nn1 +CCC(=O)N(C)c1ccccc1C(=O)Nc1ccc(-c2nc[nH]n2)cc1 +CCN(Cc1cccc(C(N)=O)c1)c1cccc(F)c1 +CC(=O)c1cnc(N2CC(C)OC(C)(C)C2)s1 +CCOC(=O)c1ccc(NC(=O)Nc2nncs2)cc1 +CCOc1ccccc1CCC(=O)NCc1ccco1 +CCc1nn2c(C)c(C(C)=O)nnc2c1-c1ccc(F)cc1 +c1csc(C2CN(Cc3ccc(-n4cncn4)cc3)CCO2)n1 +O=C(OC1CCCCC1)c1cccc(-n2cccn2)n1 +CNC(=O)c1ccc(NC(=O)NCc2ccc(OC)cc2)cc1 +COc1ccccc1C1CCN(C(=O)C(C)Sc2ccccn2)C1 +COc1ccc(-c2cc(C(=O)N3CCOCC3)ccn2)c(C)c1 +COc1ccc(F)cc1NC(=O)N(CCC#N)Cc1ccco1 +COc1ccc(COc2ccccc2NC(C)=O)cc1F +CC(C)COC1CCN(C(=O)c2ccccc2C(F)(F)F)CC1 +COc1ccc(C)cc1-c1cc(C(=O)OC(C)C)n(C)n1 +COCCNC(=O)NCCc1nc2ccccc2s1 +O=C(Nc1ccnn1Cc1ccc(Cl)cc1Cl)c1ccc[nH]1 +CCNC(=O)C1(NS(=O)(=O)c2cccc(F)c2)CCCCC1 +O=C1CSc2ccc(NCc3cccc(-c4ccncc4)c3)cc2N1 +O=C(NCc1ccccc1-n1ccnc1)c1cc(F)cc2[nH]cnc12 +O=C(Nc1ccc(F)cc1F)c1ccccc1F +NC(=O)COc1ccc(C=c2sc3n(c2=O)CCN=3)cc1 +Cc1ccc(C(N)=O)c(N2Cc3cnn(CCO)c3C2)n1 +CNC(=O)NCC(=O)NCCCC(=O)N1CCc2ccccc21 +COc1ccccc1NC(=O)CSc1nccn1Cc1ccco1 +N#Cc1c(F)cccc1N1CCN(Cc2ccon2)CC1 +COc1ccc(N2CC(NC(=O)C3CC3)CC2=O)cc1 +Cc1ncc(CN(C)C(=O)c2cc(F)ccc2N)s1 +O=C(Nc1cc2c3c(c1)CCC(=O)N3CCC2)c1cccs1 +Cc1ccccc1OCCN1CCN(CC(F)F)CC1 +Cc1cc(C)n(-c2ccc(NC(=O)NCc3ccccc3)cn2)n1 +NC(=O)c1cccnc1NCc1ccc2c(c1)OCO2 +Cc1ncc(CNC(=O)c2cccc3cn[nH]c23)s1 +Cc1ccc(C)n1-c1c(C(=O)NC2CCCC(C(N)=O)C2)cnn1C +N#Cc1ccc(-c2ccc(C(=O)N3CCCCC3)cc2)cc1O +CCc1onc(C)c1NC(=O)NCCc1cc2ccccc2o1 +CC(Oc1cccc(C#N)c1)C(=O)c1ccc(NS(C)(=O)=O)cc1 +COC(C)(C)c1noc(-c2cc3cnn(C(C)C)c3nc2C)n1 +O=C1c2ccccc2S(=O)(=O)N1Cc1cnn(-c2ccccc2)n1 +COCc1nc(NC2CCCC2)c(N)c(OC)n1 +O=C(c1ccsc1)N1CCCC(Nc2ncnc3c2CCC3)C1 +Nc1cc(Cl)ccc1NC(=O)Cn1ccccc1=O +Cn1c(CCNC(=O)N2CCCC2)nnc1SCc1ccccc1 +Nc1ccc(SCC(=O)Nc2ccccc2)c(Cl)c1 +O=C(NCc1cccnc1OC1CCCC1)Nc1nccs1 +Cc1ccc(C(=O)N2CCN(CCn3nc(C)cc3C)CC2)cc1 +COC(=O)c1cccc(NC(=O)CC(C)C(N)=O)c1 +CCc1ccccc1NC(=O)Cn1[nH]c(=O)c2ccccc2c1=O +CCN1CC(C(=O)Nc2cnn(CC(=O)OC)c2)CC1=O +O=C1NC(c2ccc(OCc3ncon3)cc2)Nc2ccccc21 +O=C(CCCNc1ncccn1)N1CCCC(n2cccn2)C1 +COc1cc(C)c(Cl)cc1-c1nnc(CCO)o1 +CCC(CCO)NC(=O)Nc1ccc(C)c(Cl)c1 +CCOc1ccc(CNC(=O)c2ccc(OCC)cc2)cc1 +CNc1cc(C2CN(Cc3ccc4[nH]ccc4c3)CCO2)nc(C)n1 +CNC(=O)c1n[nH]c2c1C(c1ccc3cccc(O)c3n1)CC(=O)N2 +CCOC1CCCN(C(=O)c2cc(N)c(C)s2)C1 +CCc1c(C)sc(NC(=O)c2cc(NC(C)=O)ccc2F)c1C#N +CCN(CC)C(=O)CSc1nnc(C2CCCCC2)o1 +COc1cccc(CNc2ccc(S(=O)(=O)C3CCCC3)cc2)c1 +CS(=O)(=O)N1CCC(NC(=O)CCc2cccnc2)CC1 +CCCS(=O)(=O)c1ccc2c(c1)NCC(CC)O2 +COC(=O)c1nnsc1NC(=O)c1ccc(Cl)cc1Cl +CC(=O)NCCNC(=O)NC1CCSc2ccccc21 +Cc1nc(NCc2ccncc2)cc(-c2ccccc2F)n1 +COCCCNC(=O)NCC1(c2ccccc2)CCOCC1 +O=C(Cc1ccc(O)cc1)NCCOc1ccc(Cl)cc1 +CN(CCC#N)S(=O)(=O)NC1CCCCCC1 +O=C(c1cncc(F)c1)N1CCCc2cccc(O)c21 +CNC(=O)c1cc(NC(=O)NCc2ccc(F)cc2)ccc1F +CCn1cc(C(=O)NCCc2cccs2)c(=O)c2cc(F)ccc21 +COCCN(Cc1ccncc1)C(=O)C1CCN(C(=O)C2CC2)CC1 +O=C(CCc1nc2ccccc2c(=O)n1C1CC1)N1CC(O)C1 +N#CCCN(C(=O)Cc1c(F)cccc1Cl)C1CC1 +COc1ccc(N2CC(NC(=O)N(C)C3CCCCC3)CC2=O)cc1 +CC(Oc1ccc(-n2cnnn2)cc1)C(=O)Nc1cccc(F)c1 +Cc1nc(-c2cccs2)sc1C(=O)Nc1c(C)n[nH]c1C +CC(=O)Nc1cccc(C(=O)Nc2ccnn2Cc2ccc(C)o2)c1 +CCc1onc(C)c1NC(=O)C(C)CN(C)C(=O)OC(C)(C)C +Cc1nn(C)c2ncc(NC(=O)NC(C)CC(O)c3ccco3)cc12 +CCC(NC(=O)NCc1cnc(C)s1)c1cccc(Cl)c1 +CC(C)N1C(=O)C(Cc2ccccc2F)Oc2ccc(O)cc21 +Cc1ccc(OCC(=O)N(C)c2ccccc2)nc1 +COc1ccc(CC(=O)NCC(O)c2ccc(Cl)cc2)cc1OC +COC(=O)c1cnc(NC(=O)c2cc3cc(Cl)ccc3o2)s1 +Cc1ccc(S(=O)(=O)Cc2noc(C(C)C)n2)cc1 +CC(C)C(NC(=O)c1ccccc1F)C(=O)NCC(=O)NC1CC1 +CC(=O)c1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)c2C)cc1 +Cn1cc(Br)cc1C(=O)Nc1ccc(OC(F)F)cc1 +COc1ccc(C(C)NC(=O)Nc2c(C)cc(C)cc2C)cc1OC +N#Cc1ccc(N2CCN(C(=O)c3ccc(Cl)cc3)CC2)nc1 +O=C(CNC(=O)c1ccsc1)N=c1[nH]c2ccccc2[nH]1 +CCCCc1c(CO)nnn1Cc1cccc(F)c1 +c1ccc(Nc2n[nH]c3c2CN(Cc2ccncc2)CC3)cc1 +CCOC(=O)C(N)Cc1nccn1-c1ccccn1 +O=C(Nc1nnc(Cc2cccs2)o1)c1ccc2ncsc2c1 +CN(Cc1ccncc1)C(=O)Nc1ccc(F)c(C#N)c1 +CNC(=O)c1cc(S(=O)(=O)N(C)c2ccccc2OC)ccc1C +COC(=O)CSc1nnc(N)n1CC(=O)OC +COCc1nc(C(=O)Oc2cccc3ccccc23)cs1 +O=c1ccc2ccc(OS(=O)(=O)c3ccccc3F)cc2o1 +COC(=O)c1cc(-c2ccc(O)c(OC)c2)ccc1F +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)Nc1cccc(C(N)=O)c1 +O=C(CSc1nnc(NC(=O)c2ccccc2)s1)NC1CC1 +CN(C)C(=O)NCCNC(=O)c1ccc(Cl)c(F)c1 +O=C(NCc1ccccc1)c1ccccc1NC(=O)N1CCOCC1 +NC(=O)c1oc2ccccc2c1NC(=O)c1cccc(C(F)(F)F)c1 +Cc1ccc(C(C)NC(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)s1 +CCC(C)C(NC(=O)c1ccc(N2CCCCC2=O)cc1)C(N)=O +O=C(c1ccccc1NCCOc1ccccc1F)N1CCOCC1 +CC(C)(C)OC(=O)N1CCCC2(CCNCC2=O)C1 +CCC(=O)NCC(=O)NCC(C)(O)c1ccc(F)cc1 +CC(C)n1nc(COc2ccccc2)c2c1CCCC2=O +CCCC(=O)N1CCN(S(=O)(=O)c2cc(F)ccc2F)CC1 +CCOC(=O)c1cnc(Nc2nc3ccccc3o2)nc1N +COc1ccccc1CNC(=O)c1cc(Cl)c2c(c1)OCO2 +CC(c1ccc(S(N)(=O)=O)cc1)N(C)C(=O)CCn1cncn1 +CCCn1c(=O)[nH]c2sc3c(c2c1=O)CCN(C(=O)C(C)C)C3 +COc1ccc(NC(=O)C(C#N)Cc2ccc(OC)c(OC)c2)cc1 +O=S(=O)(NCC(O)c1cccs1)c1ccc2ccccc2c1 +Cc1nc2cc(C(=O)OC3CCCC3n3cccn3)ccc2n1C +CCN(Cc1ccccc1C)C(=O)c1ccccc1OCC(N)=O +COC(=O)CC(NC(=O)c1cccc(OC)c1)c1ccccc1 +COC(=O)c1ccc2c(c1)CCN2C(=O)Cc1cccs1 +CN1CC(NC(=O)CCCNC(=O)c2cccs2)CCC1=O +COc1ccc(CNC(=O)NCC2CCCO2)cc1F +CC(C)Oc1ccc(C(=O)N2CC(=O)Nc3ccccc32)cn1 +CCOC(=O)c1c(C)oc2c(OC)cc(O)cc12 +CC(Cn1cncn1)NC(=O)N1CCN(Cc2ccccc2)CC1C +CC(=O)Nc1ccc(S(=O)(=O)N(C(C)C)C(C)C)cc1 +CC1CC1NC(=O)c1ccc(Oc2cccnc2)cc1 +CC1(NC(=O)CN2CCCOC2=O)Cc2ccccc2C1 +Cc1nn(CC(=O)c2ccc(CC(C)C)cc2)c(=O)c(C#N)c1C +COC(=O)c1ccc2c(cnn2-c2cccc(N)c2)c1 +Cc1cc(Nc2ncccn2)cc(C2CCCN(S(C)(=O)=O)C2)n1 +NC(=O)CC1CCN(C(=O)CCCc2ccccc2)CC1 +O=C1CCCc2c(OCc3nc(C4CC4)no3)cccc21 +CC(=O)N1CCN(S(=O)(=O)c2ccc(F)c(C)c2)CC1 +CN1CCOC2CN(S(=O)(=O)Cc3ccc(F)c(Cl)c3)CC21 +CCC(Oc1ccccc1)C(=O)NCc1nc(-c2ccccc2)no1 +COc1nn(C)c2c1CCCN(C(=O)Nc1ccccc1C)C2 +CCN(C)S(=O)(=O)N(Cc1cccc(Br)c1)C1CC1 +CC(c1ccccc1)S(=O)c1ccccc1S(C)(=O)=O +CCC(C)CS(=O)(=O)NCC1CN2CCCCC2CO1 +O=C(c1cccc2c1OCO2)N1CCC(O)(C(F)(F)F)CC1 +O=C(c1cc2c(s1)CCC2)N1CCN(c2cnccn2)CC1 +N#Cc1ccc(C(=O)Nc2cccn(Cc3ccc(F)cc3)c2=O)cc1 +CCn1cc(NC(=O)N2CCc3sccc3C2)cn1 +COc1ccc2c(c1)nc(CCO)n2-c1ccncc1 +CCOc1ccccc1-c1noc(CSc2nnnn2C(C)C)n1 +O=C(c1cnc2n(c1=O)CCS2)N(CC1CCOC1)C1CC1 +O=C(OCC(=O)c1ccccc1F)c1cccc(O)c1 +CNC(=O)c1ccccc1OS(=O)(=O)c1cc(C)ccc1C +CC(C)(C)C(=O)CN(c1ccncc1)S(=O)(=O)c1ccccc1 +Cc1ccccc1OCC(=O)Cc1ccccc1F +CC(C)(C)OC(=O)N1CCCC1c1nc2ncccc2[nH]1 +COc1ccc(NC(=O)CCSc2nnc(C(C)C)o2)cc1 +Cc1cc(C)cc(NC(=O)Cn2cnc(C)cc2=O)c1 +CC(=O)Nc1cccc(NCCN2CCCc3ccccc32)c1 +Cc1cccc(C2(CNC(=O)C3CCC(=O)N3)CCCC2)c1 +COC1C(CO)OC(n2ccc(N)nc2=O)C1O +CCn1cc(C(=O)NCCc2c[nH]cn2)c(=O)c2ccc(C)nc21 +CCc1ccc(S(=O)(=O)Oc2ccc(S(C)(=O)=O)cc2)s1 +CCC(CC(=O)N1CCC(O)C1)c1ccc(OC)cc1 +CCCCS(=O)(=O)NCc1nc(C(C)(C)C)no1 +CCC(=O)N1CCc2cc(CNC(=O)c3ccc(Cl)cc3)ccc21 +Cn1cnnc1S(=O)(=O)C1CCN(C(=O)Cn2cccc2)CC1 +CCc1onc(C)c1NC(=O)C1CCN(c2ccc(C)c(C)c2)C1=O +CCc1nnsc1C(=O)NC1CCCc2c1cnn2C +CCOc1c(N)cc(C)cc1-c1cc(C(=O)OC(C)C)[nH]n1 +CC(C(=O)N(C)C(C)C)N1CCc2ccc(Cl)cc2C1 +CCC1CN(Cc2cnc(-c3ccccn3)s2)CC(C)O1 +Nc1nc(-c2cccs2)ccc1C(=O)Nc1ccccc1 +CC(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O +Cc1cnc(NC(=O)CSc2ncc(F)c(N)n2)s1 +O=C(c1ccco1)N1CC(OCc2ccc(F)cc2)C1 +Cc1[nH]c2ccc(C(F)(F)F)cc2c(=O)c1C(C)C +CC(C)(Oc1ccc(Cl)cc1)C(=O)NCc1ccncc1 +CCCNC(=O)C(C)NC(=O)COc1ccc(Cl)cc1 +COC(=O)c1cc(-c2cc(Cl)c(OC)c(OC)c2O)nn1C +O=C(Cc1csc(COc2ccc(Cl)cc2)n1)NC1CC1 +CC1CCC(NC(=O)CN(C)S(=O)(=O)c2ccc(F)cc2)CC1 +CN(C(=O)c1cccc(OCC(F)F)n1)C1CCC1 +Cn1nnnc1SC1CCc2ccccc2NC1=O +COc1cc(=O)n(-c2ccccc2)nc1C(=O)Nc1cc(C)cc(C)c1 +CC(=O)c1sc(CNc2ccccc2F)nc1C +COc1ccc(OC)c(S(=O)(=O)NC2CCC(C)CC2)c1 +CCn1ccnc(NC2(CO)CCC(C)CC2)c1=O +Cc1nnc(CNC(=O)CNC(=O)c2cc(F)cc(F)c2)n1C1CC1 +CCn1nc(C)c(CCC(=O)Nc2nc(C)c(C)s2)c1C +CN(C)S(=O)(=O)c1csc(C(=O)Nc2cccc(O)c2)c1 +COc1cc(Br)c(OC)c(C(=O)OCC(N)=O)c1 +Cc1cc(OCC(=O)OCC(=O)NC(C)(C)C)ccc1Cl +c1ccc(-n2c(SCCc3ccncc3)nnc2-c2ccco2)cc1 +COc1cc(CNc2ccc(Cl)cc2)cc2c1OCCO2 +Cc1noc(C)c1C(C)NC(=O)Nc1cc(-n2cnnn2)ccc1F +O=S(=O)(Cc1coc(-c2cccc(Cl)c2)n1)c1ccccc1 +CC(OC(=O)c1ccc(=O)n(Cc2ccccc2Cl)c1)C(N)=O +CCCCNC(=O)c1ccc(NC(=O)C2CC2)cc1 +N#CCCN(Cc1ccccn1)Cc1cc(O)ccc1Br +Cc1cccc2c1cnn2CCC(=O)NCc1ccc2c(c1)OCO2 +Nc1ccc2c(c1)N(Cc1ccccc1Cl)CCS2 +N#Cc1c(-c2ccccc2)c(C#N)c(=O)n(N)c1N +Cc1occc1-c1n[nH]c(C(N)c2ccc(Cl)cc2)n1 +Cc1cc(NC(=O)CNc2cc(Br)ccc2C)on1 +O=C(Cn1nc(-n2cccn2)ccc1=O)Nc1ccccn1 +COc1ccccc1CCC(=O)Nc1ccc(NC(C)=O)cc1 +CCN(CC(=O)NC(C)(C)C)C(=O)CCC(C)(C)C +CCn1c(SC(C)C(=O)OC)nnc1-c1ccco1 +CC(OCc1ccccc1)C(=O)Nc1cccc(Oc2cnccn2)c1 +O=C(Nc1nc[nH]n1)c1cc(Cl)c2c(c1)OCCCO2 +O=C(Cc1ccccc1Cl)NCC(=O)Nc1nccs1 +O=C(CSc1ccccc1F)Nn1cnc2ccccc2c1=O +COC(=O)c1ccccc1C(=O)OCC(=O)c1ccccc1 +CCC(=O)Oc1ccc(C(=O)Nc2ccc(C)c(C)c2)cc1OC +O=C(NCC1(c2ccccc2)CCCC1)C1CCC(=O)N(C2CC2)C1 +COc1cc2c(cc1OC)CN(Cc1ccccc1)C(=O)CC2 +COc1ccccc1COC1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1nn(C)c(C)c1CC(=O)OCC1CCCO1 +Cc1nn(-c2ccccc2)c2[nH]c(=O)c(C#N)c(-c3ccco3)c12 +CC1(C)CS(=O)(=O)N(c2cc(Cl)ccc2Cl)C1=O +CCCC(=O)NCC1CCCN(C(=O)c2ccc(C)s2)C1 +O=C(NCc1ncccc1F)N1CCOCC1C1CC1 +COc1cc(C)sc1C(=O)Nc1ccc(F)c(F)c1 +Cn1ccc(CNC(=O)c2cccc(-c3ccoc3)c2)c1 +O=c1cc(C(F)(F)F)nc(CNc2ccccc2OC(F)F)[nH]1 +COc1ccc(-c2nnn(CC(=O)N3CCOCC3)n2)cc1 +Cc1cc(NS(=O)(=O)c2ccc(Br)cc2N)n(C)n1 +O=C(Nc1nc(-c2cccnc2)cs1)c1ccccc1Cl +Cc1cc(C)c(C(N)=O)c(NC(=O)Nc2ccc(Cl)cc2)n1 +CC(Oc1ccccc1Cl)C(=O)N(C)C(C)C(O)c1ccccc1 +CCOc1cccc(NC(=O)COc2ccc(OC)cc2)c1 +COc1ccc2c(CC(=O)Nn3cnc4ccccc43)coc2c1 +COCCOc1ncccc1C(=O)Nc1nnc(C)s1 +COc1ccc2oc(=O)cc(COC(=O)c3ccccc3N)c2c1 +COc1nc(C)nc(NCc2ccc(F)cc2)c1N +Cc1nn(C)c2nc(N3CCC(Oc4cccnc4)CC3)sc12 +O=C(Nc1ccc(-c2nnc3ccccn23)cc1)c1ccccn1 +O=C(CCc1cccc(Br)c1)NC1CCCCC1O +COc1cc(NC(=O)c2ccc(SC)cc2)ccc1NC(C)=O +CC(C)N(Cc1ccccc1)C(=O)C1CC(=O)N(Cc2ccco2)C1 +COc1c(C)cnc(CN(C)S(=O)(=O)NCc2ccccc2)c1C +CCc1nnc(NC(=O)Cn2nnc(CCCO)c2C)s1 +COc1cc(-c2noc(CC3(O)CCCCC3)n2)ccn1 +COC(=O)c1ncn(Cc2cc(=O)oc3cc(C)c(C)cc23)n1 +O=C(CSc1c[nH]c2ccccc12)Nc1nccs1 +CC(C)CC(C)OCCC(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +CC(Sc1nncs1)C(=O)NC(C)c1ccccc1Cl +Cc1n[nH]c(C)c1S(=O)(=O)Nc1cnn(Cc2cccc(F)c2)c1 +CC(C)CC(=O)N1CCC(NC(=O)C2CCCc3ccccc32)CC1 +Cc1nc2ccccc2n1CC(=O)N1CCn2c(nnc2C(C)C)C1 +COCc1cccc(C(=O)NCc2cc(F)cc(F)c2)c1 +Cc1ccc(C(=O)N2CCC(n3cc(C(C)(C)O)nn3)CC2)c(F)c1 +COc1ccccc1CCNC(=O)COc1ccc(C#N)cc1 +Cc1c(CN2CC(c3ccccc3)OCC2(C)C)cc(C#N)n1C +N#Cc1ccccc1CNCc1cccc(F)c1F +CCOc1ccc(NC(=O)CNC(=O)c2ccccc2OC)cc1F +N#Cc1ccc(OS(=O)(=O)c2cccc(C#N)c2)cc1 +CC(C)c1nc(CCNC(=O)c2cn(C)nc2C(C)(C)C)cs1 +C#Cc1cccc(NC(=O)CNC(=O)c2cccc(OC(F)F)c2)c1 +Cc1ccccc1Nc1nc(N)nc(CN(C)CCC(F)(F)F)n1 +COCc1nc(C)c(C(=O)N(C)CCC(=O)OC)s1 +Cc1noc(CCCC(=O)Nc2ncc(C)s2)n1 +Cc1ccc(CC(=O)N(CC(F)(F)F)c2nc(C)cs2)cn1 +CNC(=O)c1ccc(CSc2nc(Cc3cccs3)n[nH]2)cc1 +CC(O)c1nc2ccccc2n1Cc1nccn1C +COc1ccc(S(=O)(=O)NC2CCC(O)CC2)cc1Cl +CCCc1cc(N2CCC(=O)CC2)nc(-c2ccc(OC)cc2)n1 +Cc1nc(NC(=O)c2coc(NC(=O)c3ccccc3)n2)sc1C +O=C(CSc1nncn1-c1ccccc1)NC1CCCCCC1 +CCNC(=O)C1(NC(=O)CN(C)c2ccc(C#N)cn2)CCCCC1 +CCn1cc(C(=O)Nc2ccc(SC(C)(C)C)cc2)cn1 +Cc1cnc(C(=O)Nc2ccc(Oc3ccc(C#N)cc3)cc2C)cn1 +Cc1cc(C)nc(N2CCC(C(=O)NC3CC3)CC2)n1 +CCOc1c(Cl)cc(Cl)cc1CNc1nnnn1CC +CC(=O)c1ccc(C(=O)NC(C#N)c2ccccc2F)cc1 +CN(CCC#N)Cc1ccccc1Br +Cc1ccc(-n2nnc(-c3cccs3)c2N)cc1Cl +CC1CCCCN1C(=O)NCc1ccc(CN2CCCC2=O)cc1 +COc1ccc(F)cc1NC(=O)CCc1nc(-c2ccccn2)no1 +COc1cc(Cl)ccc1C(=O)NC1CCN(C(C)=O)CC1 +O=C(CC1(O)CCCC1)NCC1(CN2CCOCC2)CCCCC1 +O=S(=O)(N1CCCCCC1)N1CCCC1c1ccccc1 +Cc1cc(C)n(Cc2ccc(C(=O)N(C)Cc3cn(C)nc3C)o2)n1 +O=C(CN1CCn2c(nnc2C2CC2)C1)NCCc1ccsc1 +CCc1nc(COC(=O)C(C)NC(=O)c2cccs2)cs1 +O=C(NCc1cc2ccccc2o1)NCc1nnc2ccccn12 +O=C1CCCN1c1ccc(S(=O)(=O)NC(C2CC2)C2CC2)cc1 +CCN(C)c1ccnc(C2COCCN2C(=O)c2sccc2C)n1 +COc1ccc(Nc2nc(C)cc(C)c2C(N)=O)cc1 +O=C(c1ccccc1C(F)(F)F)N1CCc2c(nc[nH]c2=O)C1 +Cc1c(Cl)cccc1S(=O)(=O)N=c1[nH]cccc1C +CC(C)c1cc(CNC(=O)c2ccc(-n3ccnn3)cc2)on1 +Cc1ccc(CN(C)C(=O)Cc2ccc(O)cc2)o1 +CC(=O)c1cccc(S(=O)(=O)NCC(C)c2ccccc2)c1 +COC(=O)C1=C(C)C(C(=O)NCCc2cn3ccccc3n2)=NC1C +COCc1ccc(CNC(=O)C(C)NS(C)(=O)=O)cc1 +COc1cn(C)c(C(=O)NCc2ccccc2Cl)cc1=O +COc1ccc(CNC(=O)c2c[nH]c3ccccc3c2=O)cn1 +CC(C)COC(=O)Nc1ccc2nc(CCC(C)O)[nH]c2c1 +COc1ccc(NC(=O)Cn2ccnc2)c(OC)c1 +COCc1nc(CNc2ccc(SC)c(Cl)c2)cs1 +O=C(NCc1ccc(Cl)cc1)C1CC(=O)N(C2CCCC2)C1 +CC(C)c1cc(C(=O)NCC(C)(C)c2ccncc2)n(C)n1 +CN(C)c1ncnc(Nc2cc(C(F)(F)F)ccc2Cl)c1N +c1cnc(N2CCCC3(CN(Cc4ccoc4)CCO3)C2)cn1 +CN(CC(N)=O)C(=O)COc1ccc(Br)cc1 +Cc1ccc(-c2ncc(Sc3nc(C)cc(=O)[nH]3)o2)cc1 +Cc1nc2ccc(NC(=O)Cc3ccc(-n4cnnn4)cc3)cc2o1 +CC(NC(=O)c1cn(-c2ccccc2Cl)nn1)c1cccnc1 +C=CCOc1ccc(C=Cc2ncc(C(=O)NC)s2)cc1OC +CCC(C)NC(C#N)c1cc(Cl)c2c(c1)OCCO2 +Cc1cc(C(=O)NC2CCCN(c3ccc(F)cc3C)C2)c(C)o1 +O=C(NC1CCN(C(=O)c2ccco2)CC1)C1CCCO1 +O=C(NCCCn1cnc2ccccc21)c1ccccc1F +CCOC(=O)CSc1nc(C2CC2)n(-c2ccccc2)n1 +CCOC(=O)CCNC(=O)NC1CCC(C)CC1 +COc1ncnc2c1CCN(S(=O)(=O)c1ccccc1C)C2 +Cc1ccc(C(=O)NCC(=O)NCc2cccnc2)cc1 +NC1C(=O)N(Cc2ccc(Cl)cc2)c2ccc(F)cc21 +CCOc1ccc(NC(=O)C2CNc3ccccc3O2)cc1 +COCc1cccc(C(=O)N(C)Cc2ccc(C#N)cc2)c1 +CCCCc1nc(-c2nccn2Cc2ccncc2)c[nH]1 +COc1ccc(Br)cc1N1CCCS1(=O)=O +CCN(CC(=O)NC(C)C)C(=O)C(C)(C)c1ccc(F)cc1 +CC1CN(C2CCN(C(=O)c3ccc4ccccc4c3)CC2)CCO1 +CS(=O)(=O)NCC(=O)N1CCCC1Cc1ccccc1 +CCC(=O)Nc1cc2[nH]ncc2cc1Br +CNC(=O)COC(=O)c1cc(Cl)c(OC)c(Cl)c1 +CCOC(=O)c1cccc(N2CC(C(=O)OCC)CC2=O)c1C +Cc1ccccc1-c1noc(CNc2ccccc2N2CCCC2=O)n1 +Cc1cnc(C(=O)OCC(=O)N2C(C)CCCC2C)cn1 +O=C(C1CCCN(c2ccc(-n3cncn3)nn2)C1)N1CCCCC1 +COCCCN(Cc1ccncc1)C(=O)c1cc(F)ccc1F +COC(=O)C(NC(=O)CSc1ccccc1Cl)C(C)C +Cc1ccc(C(=O)Nc2ccc(CC#N)cc2)cc1NS(C)(=O)=O +Cc1ccoc1C(=O)N1CCn2cnc(COCC3CC3)c2C1 +CC(c1ccccc1F)N1CCn2c(nn(C)c2=O)C1 +O=C(NCc1cccnc1)c1cc2cnccc2nc1C(F)(F)F +O=C(OCC1CC=CCC1)c1cccc(-n2cccn2)n1 +CCOC(=O)C1CCN(S(=O)(=O)CCOC)CC1 +FC(F)(F)c1cccnc1CN(Cc1ccco1)CC1CCCO1 +COc1ccccc1NCC(=O)Nc1ccccc1SCC#N +CCC1CN(C(=O)NCc2ccc(C)cc2N(C)C)CC(C)O1 +Cc1c(C(=O)NCC(=O)C(C)(C)C)oc2ccccc12 +O=C(NCCCc1nnc2ccccn12)Nc1cnc(C2CC2)nc1 +CCCN(CC(=O)N(C)C)C(=O)C(c1ccccc1)c1ccccc1 +COc1cccc(C(=O)NCc2cc(-c3cccs3)on2)c1 +O=C(Cc1cn2ccsc2n1)N1CCCC1C1CCCC1 +O=C(NCc1cccs1)Nc1cccc2ncccc12 +CC(=O)c1ccc(NC(=O)c2ccc(C)s2)cc1 +O=C(Cn1ccnn1)Nc1nc(-c2ccccc2)c(-c2ccccc2)o1 +COc1ccc(S(=O)(=O)N2CCCCCC2)cc1C(N)=O +COc1ccnc(Nc2ccc(NC(C)=O)c(OC)c2)n1 +OCC(O)Cn1c(Cc2cccc3ccccc23)nc2ccccc21 +C=CCNC(=O)CCC(C#N)c1ccccc1Cl +CC(NCC(O)c1cc(Cl)ccc1Cl)c1ccco1 +O=C(CNC(=O)c1ccccc1F)Nc1ccc2c(c1)OCCCO2 +O=C1NCCCCC1Oc1ccc(Br)cc1 +CN(C(=O)CCC(C)(C)C)c1ccccc1S(C)(=O)=O +CC(C)(C)OC(=O)N1CCC(CS(=O)c2ccc(F)cc2F)C1 +CC(C(=O)Nc1ccc(C#N)cc1)N1CCN(C(=O)C2CC2)CC1 +O=C(NC1CCOC2(CCCC2)C1)c1cccc(OCC(F)F)n1 +CCN(CC)C(=O)Nc1ccc(S(=O)(=O)C2CCCC2)cc1 +N#Cc1ccccc1Cn1nncc1-c1ccc2c(c1)OCCO2 +COc1ccc(-n2cc(C(=O)Nc3cccc(C)n3)ccc2=O)cc1 +COCCOc1cccc(NC(=O)Nc2ccc(OC)cc2)c1 +Cc1ccnc(NC(=O)C2COc3ccc(Cl)cc3C2)c1 +Cc1ccc(O)c(NC(=O)C2CC2c2ccco2)c1 +CC(Oc1ccccc1)C(=O)NCCc1ccsc1 +O=C(Oc1ccccc1Br)c1ccoc1 +CC(=O)NC1CCCN(c2cccc(F)c2C(C)=O)C1 +O=C(CN1CCOC(C(F)(F)F)C1)NCc1ccccn1 +CNC(=O)CSc1nnc(N2CCCC(C)C2)n1Cc1ccco1 +Nc1ccc(Cl)cc1NC(=O)c1ccccc1O +O=c1[nH]c(N2CCCC2)nc2nccc(-c3ccco3)c12 +Cc1cccc(OCCNc2nn3c(=O)cc(C)nc3s2)c1 +COc1cc(C)c(S(=O)(=O)N2CCN(C(C)C)CC2)cc1C +O=C(NCc1ccccc1F)Nc1ccccc1F +COc1cccc(OC)c1C(N)c1nc2c(s1)CCC2 +COc1ccccc1CN(C)C(=O)Nc1ccncc1 +CCOC(=O)Cc1cc(C(=O)c2ccccc2)c(N)o1 +O=C1OCCC1N1CCN(c2nccs2)CC1 +Cc1nccn1-c1ncccc1CNC(=O)N(C)C1CCC1 +Cc1cc(=O)c(C(=O)Nc2ccccc2Nc2ccccc2)c[nH]1 +O=C(Nc1cccc(S(=O)(=O)N2CCOCC2)c1)C1CCC1 +CNC(=O)C1CN(C(=O)c2c(C)noc2C)c2ccccc2O1 +O=C(NCC(F)(F)F)c1ncc(-c2cccnc2)o1 +Nc1ccc2c(c1)C(c1ncccc1Cl)NCC2 +CCOc1ccc(C(O)CCC(=O)N(C)C)cc1 +CC(C)C(=O)N1CCC(C(=O)OCCN2CCCC2=O)CC1 +CCOC(=O)c1cc(-c2ccccc2Br)no1 +O=C1CCC(NS(=O)(=O)c2cccc(Cl)c2Cl)CN1 +COc1cc(-c2c(-c3ccccc3)ncn2CCCO)ccc1C +CC(C)CNC(=O)N1CCCC(CC(=O)Nc2nccs2)C1 +O=C(Cc1ccccc1)N1CCC(Oc2ncccn2)CC1 +C#CCNCCN(CC)c1cccc2ccccc12 +CC(=O)c1ccc(F)cc1NC(=O)c1ccc(C#N)cn1 +CS(=O)(=O)NC1CCCN(C(=O)NCc2cc[nH]n2)C1 +COc1cc(-c2cc(=O)[nH]c(N)n2)c(OC)cc1C +O=C(Cc1ccccc1)NCCC(=O)Nc1ccccc1O +Cc1ccn2cc(C(=O)Nc3ccc(C#N)cc3)nc2c1 +Cc1cc(C)c(CCCC(=O)N2CCC(O)CC2)cc1C +CCCCNC(=O)N1CCN(c2ccc(S(N)(=O)=O)cc2)CC1 +Cn1cccc1CNC(=O)CCC1NC(=O)c2ccccc2NC1=O +CC(=O)NC(C)C(=O)Nc1ccc(N2CCCCC2)nc1 +O=C(NC1CCSc2ccc(F)cc21)N1CCCCCC1 +Cc1nc(C2CCCN2Cc2nc(C)c(C)o2)no1 +COC(=O)CCCOc1ccc2cnccc2c1Br +Cc1ccsc1C(=O)OCC(=O)NCc1ccc(F)cc1F +Cc1cccc(CNc2ccc(-c3n[nH]c(C)n3)cc2)c1 +Cc1ccc(NC(=O)c2cccc(C)c2C)cc1N +COc1ccc(OC)c(-c2nc(C3CC3)c(C#N)s2)c1 +CCc1nnc(CN2CCN(CC(O)c3ccc(F)cc3)CC2)n1C +O=C1Cc2cc(NC(=O)c3ccc(Br)cc3)ccc2N1 +COc1cc(C2Nc3cc(Cl)ccc3C(=O)N2C)ccc1SC +COc1cc2c(=O)[nH]c(Cc3cccnc3)nc2cc1OC(F)F +CNS(=O)(=O)c1ccc2c(c1)CCN2C(=O)c1sccc1C +CN(C)C(=O)Sc1ccc(NC(=O)Cc2ccc[nH]2)cc1 +Cn1cnc(S(=O)(=O)NCC(=O)NCc2ccc(F)cc2)c1 +COc1c(C)cc(Cl)cc1CCn1cc(N)cn1 +COc1ccc(CCNC(=O)C2CCCN(C(=O)C3CC3)C2)cc1 +Cc1cnc(C(=O)Nc2nc3cc4c(cc3s2)OCCO4)cn1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)N(C)Cc1cc(C)on1 +NS(=O)(=O)CCNC(=O)CC1CC2CCC1C2 +COc1ccc(NC(=O)NCCc2cn3ccccc3n2)cc1 +CC(C)c1nc(CCNC(=O)C2CC=CC2)cs1 +COc1ccc2cc(NC(=O)c3cccc(C#N)c3)cnc2c1 +Cc1noc(C2CN(C(=O)c3cccc(-n4cnnn4)c3)C2)n1 +CN(C)C(=O)c1cccc(CSc2ncn(-c3ccccc3)n2)c1 +CCOC(=O)COC(=O)c1ccc(-n2cccc2)cc1 +O=C(CC1CCCN1C(=O)C1COc2ccccc21)c1ccccc1 +CCCc1noc2c1C(=O)C(C(=O)OC)C(C)(C)C2 +Cc1cccc2c1C(=O)NC(c1ccc(C3CC3C)o1)N2 +Cn1c(C(N)=O)cc2c1CN(C(=O)c1cn3ccsc3n1)CC2 +CCCc1nc(-c2ccccn2)sc1C(C)(C)O +COC(=O)N1CCN(CC(=O)Nc2nc(C)cs2)CC1 +Cc1csc(CNC(=O)Cn2c(C)cc3ccccc32)n1 +Nc1ccc(S(=O)(=O)NCc2nccs2)cc1 +CCOCCCOc1c(Cl)cc(Cl)cc1CO +CCC(C)NC(=O)CCC(C#N)c1ccccc1C +Cc1cccc(N2CCN(C(=O)c3ccc(-n4cncn4)cc3)CC2)c1 +O=S(=O)(NC1CCCCC1)c1ccc(F)c(F)c1F +CCc1nnc(CNc2ccc(Cl)cc2NC(=O)c2ccco2)o1 +Cc1ccsc1CNC(=O)Cn1nc(C)c(Cl)c1C +CCC(C)OC(C)C(=O)Nc1ccc(N)cc1C +COc1ccc2nc(SCC(=O)NCCc3ccccc3)[nH]c2c1 +O=C(NC1CC2(CCCCC2)Oc2ccccc21)C1CCOC1 +CCCCc1ccc(NC(=O)NCCN2CCOCC2)cc1 +Cc1ccnc(N2CCC(C(=O)NCC(N)=O)CC2)n1 +Cc1ccc2c(c1)CCCN2CC(O)COC(C)C +CC1CCN(C(=O)c2ccc3ccccc3n2)C(C)C1 +O=C(NCc1cc(-c2cccs2)on1)c1nc2ccccc2s1 +COc1ccc(SCC(=O)NCC(O)C2CC2)cc1 +CCC(=O)N1CCC(C(=O)N2CCC(C(N)=O)CC2)CC1 +COc1c(C)cnc(CNC(=O)c2csc3c2CCCC3)c1C +Cc1ccc(C)c(NC(=O)CSc2nc(C)nc3c2CCC3)c1 +Cc1nc(NC(=O)c2sc(-c3ccncc3)nc2C)sc1C +Cc1nonc1NC(=O)C1c2ccccc2Oc2ccccc21 +CC(C)NS(=O)(=O)c1cccc(C(=O)NCc2ccc[nH]2)c1 +COC(=O)c1ccc(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)o1 +COCc1nc(OC)c2c(C)c(C(=O)Nc3cc(C)n[nH]3)sc2n1 +Cc1ccc(OC2CCN(C(=O)CC3CCCCC3)CC2)nn1 +c1ccc(-c2csc(CN3CCCC(n4cccn4)C3)n2)cc1 +COC(=O)C(C)CNC(=O)c1c[nH]nc1-c1ccccc1F +O=C(Nc1nc2ccccc2s1)C1CN(S(=O)(=O)C2CC2)C1 +CN(C(=O)Cc1ccsc1)C1CCN(C(=O)OC(C)(C)C)C1 +C#Cc1cccc(NCC(=O)N2CCOC(C)C2)c1 +Cc1n[nH]c(C)c1CCC(=O)Nc1cnc2c(c1)c(C)nn2C +O=c1[nH]ncc(NCCc2ccc(-n3cccn3)cc2)c1Cl +Cc1sc2nc(C3CC3)nc(SCC(=O)NC(C)(C)C)c2c1C +CC(C)c1nnc(SCC(=O)c2ccc(Br)cc2)o1 +COCCn1cnnc1SCC(=O)N1CCc2ccccc2C1 +C=CCCCN(C)S(=O)(=O)c1ccc2c(c1)CCN2C(C)=O +CCOC(=O)c1cnn2ccc(NC(=O)Nc3cccc(C)c3)cc12 +CC1CC(C)CN(C(=O)NC(CCCO)c2ccccc2)C1 +Cc1ccc(NC(=O)c2c[nH]c3c(Cl)cccc3c2=O)c(C)c1 +Cc1cc(C(F)(F)F)c2nc(OCC(=O)C(C)(C)C)oc2n1 +NC(=O)c1ccsc1NC(=O)COC(=O)c1ccc(Cl)cc1 +CCOC(=O)c1cc(-c2ccc(C(F)(F)F)cc2OC)n[nH]1 +COc1ccccc1-n1nnc(CO)c1-c1ccccc1Cl +Cc1ccc(C(C)(C)C)cc1SCC(=O)NC(C)C(=O)N(C)C +CN(Cc1ccc(O)cc1)C(=O)C1CC1c1ccccc1F +Cc1ccncc1NC(=O)NCCc1nccn1Cc1ccccc1 +Cc1cccc(C2(NC(=O)c3csnn3)CCCC2)c1 +Cc1ccc(S(C)(=O)=O)cc1NC(=O)c1cc2c(s1)CCCC2 +CCOC(=O)N1CCN(CC(O)c2cccnc2)CC1 +Cn1cccc1C(=O)Nc1n[nH]c(-c2ccc(Br)cc2)n1 +OCCCN(Cc1cnc2cnccn12)CC(F)(F)F +Cc1cc(NC(=O)Cc2ccc(S(N)(=O)=O)s2)n(C)n1 +CC(C)(C)NC(=O)CNC(=O)c1ccc(C(N)=O)nc1 +Cc1cc(-n2c(C)cc(C(=O)N3CCCC(O)C3)c2C)no1 +CC(NC(=O)N1CCCC1C(C)C)c1ccccn1 +CCCOc1cccc(CN2CC(C)OCC2C)c1 +O=C(C1CC1c1cccnc1)N1CCCN(c2ncccn2)CC1 +COCC(C)NC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1 +Cc1ccc(C(=O)Nc2cccc(NC(=O)NC(C)C)c2)cn1 +COc1cccc(C(=O)NCCC(=O)Nc2ccccn2)c1 +CC(OC(=O)c1ccccc1)C(=O)NC1CCCCC1 +CC(=O)N1CCCC1C1NCCc2ccc(F)c(F)c21 +CC(=O)Nc1ccc(C)c(NC(=O)Cc2ccc(F)c(F)c2)c1 +COC(=O)c1c(NC(=O)c2ccnn2C)sc(C)c1C +COc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCCCC3)nn1 +Cc1cccc(CC(=O)NCc2nn(C)c(=O)c3ccccc23)c1 +O=C(CSc1ccccc1)NCC(=O)Nc1cccc(F)c1 +CCN(CC)c1cc(-c2ccncc2)nc(-c2ccccn2)n1 +COC(=O)c1cccc(OC(=O)c2cnn(-c3ccccn3)c2C)c1 +C=CCN(Cc1cccc(C#N)c1)C(=O)c1ccoc1 +CCn1c(C)nnc1COc1ccc(N(C)C(=O)C(C)(C)C)cc1 +COc1cccc(Nc2nnc(SCC#N)s2)c1 +CCOC(=O)c1sc(NC(=O)C2CC2c2ccccc2)nc1C +O=C(Nc1ccn(CCc2ccccn2)n1)c1cc2ccccc2[nH]1 +CC(C)(C)OC(=O)N1CCC(C(=O)NCc2ccc(C#N)cc2)CC1 +CC(C)N1CC(C(=O)Nc2ccc(N(C)C)nc2)CC1=O +CC(=O)c1cc(Cl)ccc1OCC(=O)Nc1ccccc1 +Cc1nnsc1C(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +Cc1cc(C)nc(C(C#N)C(=O)C(C)OCc2ccccc2)n1 +Cc1nc(C)c(C(=O)N(C)CCCOc2c(C)cccc2C)s1 +Cc1ccc(C(=O)NC(c2cccs2)C2CCCC2)cn1 +CCc1ccc(S(=O)(=O)NCC(O)c2ccccc2)cc1 +CCCC(C)N(C)C(=O)c1ccc(S(=O)(=O)NC)cc1 +Nc1cccc(NC(=O)CSc2ccccn2)c1 +NC(=O)C1CCCCN1C(=O)c1cnc(C2CCCO2)s1 +CC(=O)Nc1cccc(-n2nnc(-c3cccs3)c2N)c1 +COc1cccc(F)c1OC(=O)c1cnn(-c2ccncc2)c1C +CC(=O)Nc1cccc(C(=O)NCC(=O)Nc2cccc(F)c2)c1 +Cc1noc(N)c1C(=O)OCC(=O)NCC(=O)NC(C)C +CCC(CC)C(=O)N1CCCC1C(=O)N1CCNCC1 +COc1ccccc1CN(C)C(=O)Nc1nc2ccccn2n1 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1cc(F)cc2cccnc12 +CCOCC1CCCN(C(=O)C2(c3ccccc3)CC2)C1 +O=C(Cn1ccccc1=O)N1CCC(N2CCNC2=O)CC1 +COc1cc(OC)c(NC(=O)N(C)Cc2ccncc2)cc1F +Cc1noc(C(C)OC(=O)CNC(=O)c2ccc3c(c2)OCO3)n1 +COc1ccc(CNC(=O)CS(=O)(=O)c2nccs2)cc1 +Cc1ccsc1-c1nnc(CC(=O)NC(C)c2ccccc2)o1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCC2(C3CC3)CC2)n1 +NC(=O)c1ccccc1N1CCC(NC(=O)Cc2ccccc2O)C1 +NC(=O)CSc1nnc(-c2cccc(F)c2)o1 +COC(C)(C)c1noc(C2CC2c2cccc(F)c2)n1 +COc1ccc(Cl)cc1CSc1nnc(C2CC2)n1C1CC1 +O=S(=O)(Oc1ccc(-n2cnnn2)cc1)c1cc(F)cc(F)c1 +CC(=O)N(C)CC(=O)Nc1ccccc1CC(N)=O +CCn1nnc2cc(-c3noc(-c4ccc(NC(C)=O)cc4)n3)ccc21 +Cc1nn(CC(F)(F)F)c(C)c1C(C)C(=O)NCc1ncoc1C +Nc1ccc2nc(CCC(=O)Nc3ccccc3F)cn2c1 +C=CCN(Cc1ccccc1)C(=O)c1cc(OC)c(OC)cc1C +Cc1ccccc1-n1cnnc1SCC1CCCO1 +CCCc1nnsc1C(=O)N(C)CCc1scnc1C +O=C(NCCCOCC1CCOC1)c1cc2ccc(Cl)cc2[nH]1 +O=C(NCc1ccccc1Cl)C1CC(=O)N(Cc2ccccc2)C1 +COc1cccc(C(=O)NC(C#N)c2ccc(C)cc2)c1 +C#CCN1CCN(C(=O)NCCc2ccc(F)cc2C)CC1 +CCCCC1(C)NC(=O)C(C(Cl)(Cl)Cl)O1 +CCC(C)n1ncc(C(=O)NCc2cccc(C(N)=O)c2)c1C1CC1 +COCCn1cc(NC(=O)Nc2c[nH]nc2C)cn1 +CC(C)C(NS(=O)(=O)c1ccccc1)C(=O)N1CCC1 +COCCN(Cc1ccco1)C(=O)Nc1ccc(C)cc1C +CN(C(=O)c1ccc(S(C)=O)cc1)C1(C#N)CCC1 +CSc1nc2ncc3c(=O)n(-c4cccc(C)c4)ccc3n2n1 +O=C(CCc1nc(C2CC2)no1)NC1(c2cccc(F)c2)CC1 +CCS(=O)(=O)c1ccccc1C(=O)Nc1cccc(C)c1 +CCc1noc2ncnc(Nc3cccc(F)c3)c12 +O=C(COc1ccccc1)Nc1nnc(C2CCCCC2)s1 +CCc1cc(C(=O)OC)c(NC(=O)CN2CCOCC2)s1 +CCC(=O)c1ccc(OCC(=O)Nc2c(C)cc(C)cc2C)cc1 +CCNC(=O)N1CCC(Nc2cc(OC)ncn2)CC1 +Cc1c(C(=O)N(C)CCO)c(-c2ccccc2)nn1-c1ccccc1 +CC(C)NC(=O)COC(=O)c1ccc(C(F)(F)F)nc1 +O=C1CCCCN1c1ccc(F)cc1C#CCCO +COc1ccc(CN(C)C(=O)Nc2ccc(F)cc2C#N)cc1F +COc1ccc(OC)c(C(=O)Cn2nc(C)c(C)c(C#N)c2=O)c1 +CC(=O)Nc1cccc(Nc2ncnc3ccccc23)c1 +O=c1n(Cc2ccccc2F)nc2ccc(-c3ccccc3)nn12 +Cc1ccc(C(N)=O)cc1NS(=O)(=O)c1ccc2ccccc2c1 +CC(=O)Nc1ccc(NC(=O)c2cccc(F)c2N)cc1 +CC1CCCN(C(=O)NCCNC(=O)c2cccnc2)CC1 +CNS(=O)(=O)c1cc(C(=O)NCCc2ccccc2)n(C)c1 +CCOC(=O)CN(C)C(=O)c1cn(CC(C)C)c2ccccc12 +Cc1csc(CS(=O)(=O)c2nccn2-c2cccc(C)c2C)n1 +COc1cc(CNC(=O)NC2c3ccccc3CC2O)ccn1 +O=C(Nc1nc[nH]n1)c1csc(-c2cnn(-c3ccccc3)c2)n1 +Cc1c(NCc2ccccc2C#N)cccc1S(=O)(=O)NC1CC1 +CCc1nnc(Sc2nccc(C(F)(F)F)n2)n1C +CC(C)Oc1ccc(C(=O)NCc2cn[nH]c2)cc1 +c1ccc(-c2nnc(CSc3nc(-c4ccncc4)n[nH]3)o2)cc1 +CCn1ccnc1N1CCN(C(=O)Cc2ccc(Cl)cc2)CC1 +Cc1ccc(-n2ccnc2)c(C(=O)NC(C)c2c(C)noc2C)c1 +O=C(CCNC(=O)c1ccnc(-n2cncn2)c1)NC1CCCCC1 +CCOC(=O)CCC(=O)c1c(C)oc2ccc(OC)cc12 +CCCN(CC(=O)OC)C(=O)c1cc(Cl)cn1C +CCCC1CN(S(C)(=O)=O)CC1Nc1ccc(C#N)cn1 +COc1cc(C(=O)Nc2ccc(F)cc2F)ccc1OC(F)F +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccccc1F +CC(Cc1ccccn1)N(C)C(=O)C1Oc2ccccc2O1 +Cc1nc(NC(=O)c2csc3ccccc23)sc1C(=O)N(C)C +COc1ccccc1CNc1ncc(C(=O)Nc2ccccc2)c(C)n1 +CCCCn1cnc2ccc3[nH]c(C)nc3c2c1=O +COC(=O)c1ccc(CCC(=O)N(C)c2ccc(OC)nc2)cc1 +COC(C)C(=O)N1CCCC1c1cccc(Br)c1 +CCCC(C)c1nnc(C(N)c2ccc(C#N)cc2)o1 +O=C(Oc1ccc(Cl)c2ccccc12)C1CC(=O)N(C2CC2)C1 +COc1ccnc(NC(=O)COc2ccc(Cl)cc2)c1 +Nc1ncccc1OCC(=O)N1CCCc2ccccc21 +Cc1cn2c(CN(C)C(=O)CCC3CC3)c(C)nc2s1 +CC(=O)Nc1ccc(CN2CCN(c3cc(C)nc(C)n3)CC2)cc1 +CC(=O)NCCNC(=O)c1ccc(COc2ccc(F)cc2)o1 +CCCCCCNC1=NS(=O)(=O)c2ccccc2N1 +CSc1nnnn1-c1cccc(NC(=O)C2CC3CCC2O3)c1 +CN(CC(C)(C)O)c1c(C#N)c(=O)n(C)c(=O)n1C +CN(C)C(=O)c1ccc(OCc2ccccc2Cl)cc1 +CN1CCOC(C(=O)Nc2cccn(Cc3ccc(F)cc3)c2=O)C1 +Cc1ccc(C2CCCN2C(=O)c2ccncc2F)s1 +CC(=O)c1ccc(N2CCN(C(=O)c3cc(C)ccc3O)CC2)cc1 +O=C(Cc1nnc(-c2cccs2)o1)NCCC1=CCCCC1 +CN1CCCN(CC(=O)NC2CCOCC2)c2cc(Cl)ccc21 +Cc1ccc(OCC(=O)NCC#Cc2ccc(C(N)=O)cc2)cc1 +O=C1CC2C(CCN2c2ncccn2)N1c1ccsc1 +Cn1cc(CCNc2ncnc3c2cnn3C)cn1 +COCc1ccc(CN2CCOC(C)(c3ccccc3)C2)o1 +CCc1noc(C2CCCCN2C(=O)c2ccco2)n1 +CCCc1nnc(NC(=O)Cc2coc3c(C)c(C)ccc23)s1 +CCc1cc(C(=O)N2CCC(c3cc4ncccc4cn3)CC2)on1 +CCn1nc(C)cc1C(=O)Nc1ccccc1OC +Cc1ccc(Oc2ccc(N)c(C(F)(F)F)c2)cn1 +O=C(Cc1ccccc1)NCc1nc(-c2ccccc2)no1 +Cc1cc(-c2cccc(-c3ccn(CCCO)n3)c2)nc(N(C)C)n1 +CCOC(=O)C1CCN(C(=O)c2cccc(NC(=O)C(C)C)c2)CC1 +CC(=O)Nc1cccc2c1ccn2CC(=O)Nc1ccc2cc[nH]c2c1 +CCC(C)(CNC(=O)c1cnc2onc(C)c2c1)N1CCOCC1 +O=C(CCC(=O)N1CCOCC1)Nc1ccc2c(c1)CCC2 +Cc1nc(Cc2ccc(F)cc2)sc1C(=O)NCc1cscn1 +COCC(NC(=O)Cc1cc(Cl)ccc1OC)C(N)=O +Cc1cc(C)c(S(=O)(=O)N2CCCC(CO)C2)c(C)c1 +COc1ccncc1NC(=O)c1ccc(F)c(COCC2CC2)c1 +O=S(=O)(CCCCS(=O)(=O)c1ccccc1)c1ccccc1 +O=C(NCc1cccc(O)c1)Nc1cccc(Cl)c1 +Nc1cccc(CC(=O)NCCc2cccs2)c1 +Cc1cccc(NC(=O)NCC2CCN(c3ncccn3)CC2)c1 +COC(=O)C1(N(C)C(=O)c2cc3c(C)nn(C)c3s2)CCCCC1 +Cc1noc2nc(C)n(CC(=O)NCc3ccccc3)c(=O)c12 +CCC(C)NC(=O)NC(C)C(=O)NCc1ccccc1 +O=C(NCC(O)c1cccs1)Nc1ccc2c(c1)OCO2 +COC(=O)C(N)Cc1ccc(-c2ccccc2)cc1 +COc1ccc2cc(CNc3ccccc3)c(=O)n(CC(N)=O)c2c1 +NC(=O)c1ccc(NC(=O)c2cccnc2OCC(F)F)cc1F +C#Cc1cccc(N(Cc2ccco2)C(=O)Cc2c(C)nn(C)c2C)c1 +C=CCn1c(C)nnc1SC(C)C(=O)OCC +O=C1CCCc2c1cnc1nc(-c3cccnc3)nn21 +CCn1cc(CC(=O)NCc2ccccn2)c2cccnc21 +CCOc1cc(C#N)ccc1OCC(=O)Nc1cc(F)ccc1F +COC(=O)c1cc(Br)cc(C(=O)OC)n1 +CCn1nnc2cc(C(=O)NCCc3ccc(C)c(OC)c3)ccc21 +O=C(COc1ccc(-n2cnnn2)cc1)NCCN1CCOCC1 +CN1CCN(C(=O)c2cc3cc(Cl)ccc3[nH]2)CC1 +CCN(CC)S(=O)(=O)c1ccc(OC)c(Cl)c1 +COCc1ccccc1CNC(=O)c1cc(NC(C)=O)ccc1F +CC(c1ccco1)N(C)C(=O)N1C(C)CCCC1C +COc1ccc(CNS(=O)(=O)c2cc(C)ccc2C)cc1 +CC(C)(C)C(NC(=O)C1CC(=O)N(Cc2ccccn2)C1)C(N)=O +CCSc1ccc(NC(=O)NCC(C)N2CCOCC2)cn1 +O=C(NCc1ccccc1-n1ccnc1)Nc1ccccc1Cl +Fc1ccc(Cl)cc1-c1nc(C2CCOC2)no1 +CC(C)CNC(=O)c1ccc(OCc2cscn2)cc1 +CC(C)(C)c1nnc(CN2CCN(C(=O)c3cccs3)CC2)o1 +CC(NC(=O)CC1CCCCC1)C(=O)N1CCOCC1C1CC1 +O=C(NCCNC(=O)c1ccc(Cl)cc1)NCC1CCCO1 +CC(=O)NCCNC(=O)CCc1c[nH]c2ccccc12 +Cn1cnc(CNC(=O)Nc2cccc(-c3ncco3)c2)n1 +COc1ccc(CNc2ncnc(NCc3ccco3)c2N)cc1 +O=C(NCC(O)c1cccs1)c1cccc2ccccc12 +O=C(CCOCC1CCCO1)Nc1cccnc1 +Cn1nc(C(=O)Nc2ccc3c(c2)OCCO3)c2ccccc2c1=O +Cc1nc(C)c(CCNC(=O)NCCc2ccc(F)cc2C)s1 +CCC(C)NC(=O)c1cc2cnn(C(C)C)c2nc1C +c1ncn(Cc2nnc(SCc3ccn(C4CCCC4)n3)o2)n1 +Cc1nc(N)nc(SCc2cccc(C(F)(F)F)c2)c1C#N +O=C(Nc1cccc2c1ccn2Cc1ccccc1)c1cccnc1 +COc1ccc(OC)c(CC(=O)Nc2ccc(C(N)=O)cc2)c1 +CC(C)(C)c1ccccc1NCC(=O)NCC(=O)N1CCCC1 +COc1ccc(NC2=NCC(=O)N2Cc2ccc(F)cc2)cc1 +COCCNc1cc(-c2cncc(C(N)=O)c2)c2cc[nH]c2n1 +CC(NC(=O)Cn1ncn(C)c1=O)c1cccs1 +CC(C)N(C(=O)C1CCN(CC(F)(F)F)CC1)c1cccnc1 +Cc1ccc(CNc2nnc(-c3sccc3C)o2)o1 +CCOCCOC(=O)Nc1ccc(Cl)cc1C +CCN(C)C(=O)Cn1cnc2ccc(Br)cc2c1=O +CC(NC(=O)Nc1cccc(CN2CCCC2=O)c1)c1ccccc1 +O=C(CCc1ccc2c(c1)CCO2)NCCCc1nc2ccccc2[nH]1 +Cc1ccc(C(=O)OCc2nc3ccccc3s2)c(=O)[nH]1 +Cc1cc(C)n(-c2ccc(NC(=O)NCC(C)C)cn2)n1 +Cc1noc(C)c1CC(=O)N(C)c1cccc2ccccc12 +Cn1cc(CNC(=O)N2CCC3(CC2)OCCO3)cn1 +Cc1ccc(-n2c(=O)[nH]cc(C(=O)Nc3ccccc3F)c2=O)cc1 +Cc1c(Cl)cccc1NC(=O)Cn1ncc(Cl)c(Cl)c1=O +Cc1nnc2c3ccc(Cl)cc3nc(N3CCC(C)CC3)n12 +COCC(=O)NC1CCN(C(=O)Cc2ccccc2OC)CC1 +COCC(=O)NC1CCC2(CCC(=O)N2Cc2ccccc2)CC1 +Cc1cccc(NC(=O)NCC(=O)NCc2sccc2C)c1 +Cc1cccc(CC(=O)N2CCOCC2c2c(C)nn(C)c2C)c1 +Cc1ccc2c(c1)oc(=O)n2C1CCN(C(=O)CC(C)C)CC1 +Cn1c(CCCNC(=O)C(C)(C)C)nc2ccccc21 +N#CCCNC(=O)COc1ccc(N)cc1Cl +Cc1ccc(C#N)cc1NCC(=O)NCC(F)(F)F +CN(C)S(=O)(=O)c1ccc(-n2cc(Br)cn2)cc1 +CCn1cnnc1CNC(=O)NCc1cnn(Cc2ccccc2)c1 +Cc1ccc(-c2ccnc(NCCSc3nc(C)n[nH]3)n2)c(C)n1 +CC(Oc1ccccc1)C(=O)Nc1cccc(C(=O)N(C)C)c1 +COc1ccc(C(O)CNCc2ccccc2)c(OC)c1 +O=C(NCC1CCOC1)c1ccc(-n2cnnn2)cc1 +CCC1CCCCN1C(=O)c1ccc(OCC(F)F)nc1 +CCCCc1nnc(NC(=O)c2ccc(Cn3cncn3)cc2)s1 +Cc1nc(C)n(C2CCCN(C(=O)c3sccc3C3CC3)C2)n1 +C=CCOc1ccccc1C1CC(=O)Nc2[nH]nc(C)c21 +Cc1ccc(F)cc1C(N)C(=O)NCCCCCO +CC(=O)Nc1ccc(C(=O)OCC(=O)Nc2cccc(Cl)c2)cc1 +NC(c1ccc(Br)cc1)c1nc2c(s1)CCC2 +CCOCCOC(=O)c1[nH]c2c(c1C)C(=O)CC(c1ccco1)C2 +COCCOCC1CCN(C(=O)c2ccccc2C)C1 +CCCNC(=O)c1cc2ccccc2cc1C(=O)OC +OCCOCCNc1ncnc2sc(-c3ccccc3)cc12 +Cc1cnn(CCC(=O)Nc2ccc(N(C)C)cn2)c1 +CC(c1nc(CCc2ccccc2)n[nH]1)n1cncn1 +CCCn1ccc(NS(=O)(=O)c2ccc(C)cc2C)n1 +CCOC(=O)N1CCN(c2nc3c(c(=O)[nH]2)CCCC3)CC1 +O=C(CNC(=O)c1ccco1)NCCCc1ccccc1 +Nc1cnc2c(Br)cc(C(F)(F)F)cn12 +Cc1csc(-c2ccc(NC(=O)N(C)Cc3ccccn3)cc2)n1 +CC(NC(=O)Nc1ccc(F)c(F)c1)c1ccc(C#N)cc1 +O=C(c1cc2cc(F)ccc2[nH]1)N1CCCCC1c1cccnc1 +COc1ccc(-n2cc(C(=O)N3CCCC3)ccc2=O)cc1 +C1=NC2=NC=NC2C(NCc2nc(Cc3ccccc3)no2)=N1 +NC(=O)Nc1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1 +CCCC1CN(S(=O)(=O)c2cnn(-c3ccc(C)cc3)c2)CCO1 +CC(=O)Nc1ccc(F)c(C(=O)N(C)C(C)c2ccc(C)s2)c1 +CC1(c2ccccc2)CN(Cc2cnc3ccc(C#N)cn23)CCO1 +Cc1cc2c(N3CCN(C(=O)c4cccs4)CC3)ncnc2s1 +CCn1ccnc(NCc2cccc(C(=O)Nc3ccccc3)c2)c1=O +COc1ccc(COC2CC3C(CC2=O)C3(C)C)cc1 +COc1ccc(CC(=O)NCCc2cccc(C(N)=O)c2)c(Cl)c1 +O=C(CC1CCCC1)Nc1ccc2nc[nH]c(=O)c2c1 +Cc1ccc(S(=O)(=O)N(CCC#N)CCc2ccccc2)cc1 +Cc1nc2cc(Oc3cccc(F)c3)c(N)cc2s1 +CC(CCC(C)(C)C)NC(=O)NCCN1CCCS1(=O)=O +Cc1ccsc1-c1nnc(CC(=O)NCC2CC2)o1 +CCC(C)n1ncc(C(=O)NCCc2ccc(F)cc2)c1C1CC1 +c1cc2ccc(NC3CC3)cc2c(OCC2CCCO2)n1 +Cc1nc(C(=O)Nc2ccc(N3CCOCC3)nc2)c2n1CCCC2 +CCn1nc(C)c(NC(=O)C2(c3ccc(C)cc3)CCOCC2)c1C +CCCCc1nnc(NC(=O)c2c[nH]nc2-c2ccccc2F)s1 +COc1cccc(-c2cc(-c3cccs3)[nH]c(=O)c2C#N)c1 +c1ccc(Cc2nnc(CN3CCN(c4nccs4)CC3)o2)cc1 +COc1ccc(C(=O)N2CCc3[nH]nc(C=Cc4ccccc4)c3C2)o1 +Cc1ccc(NC(=O)NCCNC(=O)c2ccc(C)c(F)c2)c(F)c1 +COc1cccc2cc(C(C)NC(=O)NCc3scnc3C)oc12 +Cc1ccc2ncc(C(=O)OC(C)c3ccccn3)c(=O)n2c1 +CC(Sc1ccc(Cl)cc1)C(=O)N(C)CC(=O)NC1CC1 +CCOc1ccc(C(=O)Nc2cccc(CCC(=O)N(C)C)c2)cc1 +Cc1noc(C2CN(C(=O)Cn3cnc4ccccc43)C2)n1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccc(=O)[nH]n1 +COc1cccc2c1OCC(NCc1ccc(-n3ccnc3)cc1)C2 +O=C(CCSc1ccccc1F)NCc1cn[nH]c1 +CCc1nccn1-c1ccc(-c2ccc(O)cc2)cc1 +CCc1ccccc1OCC(=O)Nc1ccccc1C(=O)NC1CC1 +Cc1cc2oc(=O)cc(CN3CCNC(=O)C3)c2cc1Cl +Cc1cc(C)cc(N2CC(C(=O)Nn3cnnc3)CC2=O)c1 +Cc1nn2cccnc2c1C(=O)OC1(C2CC2)CC1 +CCOCC1CCCN(C(=O)Nc2cccc(C(C)OC)c2)C1 +COCC(=O)NC(Cc1ccccc1)c1cccs1 +CCn1cnc2c(cnn2-c2cccc(C(F)(F)F)c2)c1=O +COC(=O)C1(NC(=O)c2cccc(OC)c2F)CCCCC1 +Cc1ccc(C(C)C(=O)N2CCCN(Cc3nccn3C)CC2)cc1 +COc1ccc(NC(=O)Nc2cn[nH]c2)cc1-n1nnnc1C +CCc1noc(-c2c(C)cc(C)n2CC(=O)Nc2ccccc2C)n1 +Cc1cc(Cl)ccc1NC(=O)COc1ccccn1 +O=C(CCc1cccs1)NCc1cccnc1OC1CCCC1 +N#CC1(NC(=O)CN2C(=O)CCCc3ccccc32)CC1 +Cc1cc(C)c(C(O)C(C)NCc2ccco2)c(C)c1 +Cc1cc(CNC(=O)Nc2ccc(-n3cnnn3)cc2)ccc1F +CCCNC(=O)CN(C)C(=O)CCc1c(C)noc1C +CC(=O)c1ccc(NC(=O)c2nccc3ccccc23)cc1C +NS(=O)(=O)N1CCN(Cc2nnc(-c3cccs3)o2)CC1 +CC(=O)c1csc(C(=O)NCC(O)c2cc3ccccc3s2)c1 +CC(CC(=O)Nc1ccc(C(N)=O)cc1)c1ccc(F)cc1 +O=C(Nc1ccc(N2CCCS2(=O)=O)cc1)c1ccc(F)cc1 +Cn1ncc2c(N3CCC(F)(F)CC3)nc(-c3ccncc3)nc21 +CC(=O)c1c(C)cc(C)c(CSc2nnnn2C)c1C +CC(=O)Nc1cccc(OCC#CCNC(=O)CC(C)(C)C)c1 +COC1COC2(CCN(C(=O)CCc3ccccc3C)CC2)C1 +COCc1nc(-c2nnc(NCC(C)C)s2)cs1 +CC1CN(C(=O)c2c[nH]c3cccc(F)c23)CC(C)O1 +COC(=O)c1cnn(-c2cc(Nc3c(F)cccc3F)ncn2)c1C +Cc1cc(C(=O)N(C)Cc2cccc3cnccc23)no1 +Nc1ccc2c(c1)CCCN2C(=O)C1COCCO1 +O=C(COc1ccc(F)c(Cl)c1)N1CCCS1(=O)=O +O=C(c1cnc2ccccc2n1)N1CCC(Cn2cccn2)CC1 +N#CCC(COc1ccc(F)cc1F)N1CCCCC1 +O=C(c1cnc2sccn2c1=O)N1CCCCCC1 +COc1ccc(C(=O)c2ccc(C)cn2)cc1OC +CS(=O)(=O)N1CCCC2(CC(Oc3ncccn3)CO2)C1 +Cc1ccccc1-c1nnc(SCC(=O)N2CCCC(C)C2)n1C +Cc1ncc(CN(C)C(=O)CCCc2ccc3[nH]c(=O)[nH]c3c2)s1 +CCOC1CCCN(CC2=NS(=O)(=O)c3ccccc3N2)C1 +CCCNC(=O)c1nsc(C(=O)NC2CCCCC2)c1N +COCCN(Cc1ccccc1)C(=O)c1ccc(-n2ccnc2)nc1 +N#CCC1NCCc2ccc(O)c(Br)c21 +CCS(=O)(=O)N1CCCC2(CCN(c3cncnc3)C2=O)C1 +Cn1c(CO)cnc1S(=O)(=O)Cc1ncc(-c2cccs2)o1 +Cc1ccc(NS(=O)(=O)c2cn(C)nc2N)nc1 +CCc1ccc(OCC(=O)Nc2cccc(-c3nncn3C)c2)cc1 +CCCn1c(=NC(=O)CSc2nncs2)[nH]c2ccccc21 +CSc1ccc(CNc2ccc(C#N)cn2)cc1 +COc1ccc(C(=O)N2CCC3(C2)C(=O)N(C)c2ccccc23)cc1 +Cc1nc(-c2cccc(OCC(=O)N3CCCCC3C)c2)no1 +O=C(Cc1cccc2nc(NCCO)[nH]c12)c1cccc2ccccc12 +COc1ccccc1C(=O)Nc1ccccc1C(=O)N1CCCC1 +CNC(=O)NCC(=O)NC(COc1ccccc1F)C(C)(C)C +CCCn1c(=O)oc2cc(NC(=O)Nc3ccccc3F)ccc21 +CC(O)CN1CCN(C(=O)Cn2nc(-c3ccccc3)oc2=O)CC1 +Cc1cccc(CCNC(=O)Cc2noc3ccccc23)c1 +OCCNc1ncnc2sc3c(c12)CCCCC3 +Cc1nc(C)c(CNCc2cccc(Cl)c2Cl)s1 +Cc1nn(CCCC(=O)NC(C)c2ccccc2)c(=O)c2nccn12 +Oc1ccc(CC2NCCc3c(F)cc(O)cc32)cc1 +Cc1cc(C)cc(Cn2c(N3CCCCC3)cc(=O)n(C)c2=O)c1 +CC(C)S(=O)(=O)NC1=NCN(Cc2ccc3c(c2)OCO3)CN1 +Nc1noc(CCNC(=O)C2(c3cccc(F)c3)CCCC2)n1 +CCCC(=O)NCC(=O)NCc1ccc(-n2ccnc2C)nc1 +Fc1ccccc1-c1n[nH]cc1CN1CCCC2(C1)OCCO2 +O=C1CC(C(=O)Oc2ccc3ccc(=O)oc3c2)c2ccccc2N1 +CS(=O)(=O)N1CCN(C(=O)c2ccccc2)C1 +Cc1cc(OC2CCCCC2N2CCOCC2)ccc1N +CN(CCOc1ccccc1F)C(=O)c1cnc2ccccn2c1=O +Cc1cccc(S(=O)(=O)CCCn2ncc(Cl)c2C)c1 +CCCNS(=O)(=O)c1ccc2c(c1)N(C(C)=O)CC(CC)O2 +Cc1cc(NC(=O)C(C)N(C)Cc2ccccc2C(F)(F)F)no1 +CCn1c(SCC(=O)OC)nnc1C1Oc2ccccc2OC1C +COC(=O)c1cc(S(=O)(=O)NCC(C)C)c(Cl)cc1Cl +CCOC(=O)C(O)c1nnc(-c2ccc(O)cc2)n1C +Cc1nc(C)c(C(=O)N(C)c2cccc3ncccc23)s1 +Nc1c(Cl)cccc1C(=O)OCC(=O)NCc1ccc(F)cc1 +CCN(C(=O)CCC(C#N)c1ccccn1)c1ccccc1 +O=C(NCCNc1cnccn1)c1cc(Cl)c2c(c1)OCO2 +O=C(CCc1c[nH]c2ccccc12)OCc1cc(=O)n2ccccc2n1 +CCNC(=O)c1ccc(NC(=O)c2c(F)cccc2F)c(C)c1 +NC(=O)c1cnc(NC(=O)Cc2coc(-c3ccccc3)n2)s1 +COc1ccc(NC(=O)c2ccccc2OC)cn1 +CC1C(=O)N(c2ccccc2F)CCN1C(=O)C1CCC1 +O=C(NCCCOc1ccc(Cl)cc1Cl)c1cc[nH]n1 +O=C(NCCc1ccccn1)c1c[nH]c2ccccc12 +Cc1ccc(C)c(C(=O)NCc2nc(C)cc(N3CCOCC3)n2)c1 +COCC1CCCN1C(=O)Nc1cccnc1F +Cc1nn(C)c2ncc(NC(=O)CN(C)S(C)(=O)=O)cc12 +COc1ccc(CCNC(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 +COc1ccc(N2CCN(CC(=O)Nc3cc(C)ccn3)C2=O)cc1 +O=C(COc1cccc(NC(=O)C2CC2)c1)Oc1ccccc1F +CSc1ccc(Cl)c(C(=O)Nc2cc(-c3ccncc3)n[nH]2)c1 +Cc1cc(CN(C)C(=O)c2c(C)cccc2N)no1 +CN(C)C(=O)c1nc(-c2ccccc2)n(-c2ccccc2)n1 +Cn1nc(C(C)(C)C)cc1NC(=O)CSc1ccccn1 +COc1ccc(S(=O)(=O)Nc2cccc(-c3cn[nH]c3)c2)cc1C +COCCCNC(=O)NC(C)c1ccccc1C(F)(F)F +CC(C)C(=O)N1CCC(NC(=O)Nc2nccc3sccc23)CC1 +Cc1n[nH]c(C2CN(C(=O)CCCc3cccs3)CCO2)n1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCC(Cc2ccccc2)CC1 +Cc1cc(NC(=O)CNC(=O)C(C)(C)C#N)ccc1Br +COc1ccccc1CCNC(=O)c1cc(C)nc2onc(C)c12 +CC(NC(=O)Nc1ccc(-n2cccn2)nc1)c1ccc(F)c(F)c1 +O=C(CN1CCN(c2ccc(F)cc2)CC1)c1c[nH]c2ccccc12 +Cc1cc(NCc2nnnn2-c2ccccc2)ccc1C(=O)N(C)C +COc1ccccc1CC(=O)N1CCC(C(=O)N(C)C)CC1 +CC(O)CN1CCN(C(=O)C2(c3cccc(Cl)c3)CC2)CC1 +COCc1cc(C(=O)Nc2cc(OC)c(OC)cc2F)ccc1F +COc1cccc(NC(=O)CNc2ccccc2F)c1 +CCN(Cc1cccc(F)c1)CC(O)c1ccc(F)c(F)c1 +Cc1cccc(-c2[nH]ncc2CNc2ccc(N3CCOC3=O)cc2)c1 +CC(=O)Nc1cccc(NS(=O)(=O)c2cc(C(N)=O)n(C)c2)c1 +CN(CC1(CO)CCC1)C(=O)Cc1noc2ccccc12 +CCC(=O)Nc1cc(-c2ccc(=O)[nH]n2)ccc1C +O=C(c1ccc(F)cc1)N1CCN(Cc2noc(C3CC3)n2)CC1 +Cc1cc(=O)c(OCc2ccc(Cl)cc2)co1 +CCC(Sc1nnc2[nH]c(=O)cc(C(C)C)n12)C(=O)OC +O=C(NCc1nnc(C2CC2)n1C1CC1)c1ccncc1F +CNS(=O)(=O)c1ccc(C(=O)N(Cc2ccccc2)C(C)C)o1 +CCC(=O)c1ccc(S(=O)(=O)Cc2cccc(C#N)c2)cc1 +O=S(=O)(N1CCCCC1)N1CCN(c2ccccc2F)CC1 +CC(NC(=O)c1ccc(F)cc1)c1ccc(C#N)cc1 +N#Cc1cnc(SCc2cc(-c3cccs3)on2)nc1N +CC1Oc2c(F)cc(Br)cc2N(C)C1=O +CN(C)c1nc2ccc(NC(=O)C3CC3c3ccc(F)cc3)cc2o1 +CCOC(=O)Nc1cccc(NC(=O)NCc2cccnc2)c1C +CC(C)C(=O)Nc1ccc2c(c1)C1(CCOCC1)CN2C(C)C +N#CCCN(CC(=O)N1CCCC2CCCCC21)Cc1ccco1 +CC(OC(=O)c1cnc2c(c1)nnn2C)c1ccc(-n2cccn2)cc1 +COC(=O)CCC(=O)NCC1(c2cccc(Br)c2)CC1 +CCOc1ccc(NC(=O)c2coc(NC(=O)c3ccco3)n2)cc1 +O=C(NCCc1cccs1)c1cc(C2CC2)on1 +COc1ccc(C(=O)CNc2cc(C)on2)cc1OC +C=CCN(CC=C)C(=O)Cn1c(C(C)O)nc2cc(C)c(C)cc21 +COCC(C)NC(=O)COc1ccccc1-c1ccccc1 +CCCCN(C)c1ncnc(Nc2cccc(C(C)=O)c2)c1N +COc1ccc(CC(=O)Nc2cccc(Cl)c2O)cc1OC +CC1(C)COCCN1Cc1cnn(-c2ccccc2)n1 +Cc1cc(CNc2ccccc2CC(=O)N(C)C)no1 +CCCNC(=O)c1cccc(NC(=O)N(C)CCC(C)O)c1 +CCCN1C(=O)CCc2cc(NC(=O)c3cc(C)nn3C)ccc21 +Cc1nnc2n1C(C)CN(C(=O)c1ccc(-c3nnn(C)n3)cc1)C2 +CC(=O)Oc1cc(C)c2c(=O)c(Oc3ccccc3)coc2c1 +Cc1cc(C)n(Cc2cc(C#N)ccc2F)c(=O)n1 +CCCNC(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +Cc1cc(C(=O)NCc2ccccc2F)nc(N2CCOCC2)n1 +O=C(NCCc1cccc2ccccc12)NCc1ccccn1 +Cc1nc(NCCc2ccco2)c2c(C)c(C)sc2n1 +COC(=O)c1oc2ccccc2c1CSc1nc(C)c(C)o1 +CCc1cc(NC(=O)c2cnn(CC(C)C)c2C2CC2)n(C)n1 +Cc1cnc(C(=O)Nc2ccc3nn(-c4ccccc4)nc3c2)cn1 +O=C(c1cc2ccccc2[nH]1)N1CC(c2nc(-c3ccccc3)no2)C1 +CCC(C)NC(=O)Nc1cccc(CN2CCCCC2=O)c1 +N#Cc1ccc(-c2noc(CCCOc3ccccc3Cl)n2)nc1 +COc1ccccc1N1CCN(C(=O)C(C)Oc2ccccc2)CC1 +CCCc1c(CO)nnn1-c1ccc(OCC(C)C)cc1 +COc1cc2c(cc1OC)CN(C(=O)CCc1ccc(F)cc1)CC2 +CCNS(=O)(=O)c1ccc(OC)c(NC(=O)c2ccccc2)c1 +CC(C)(C)OC(=O)NC1CCN(C(=O)c2ccncc2)CC1 +CC1CCCC(C)N1C(=O)COC(=O)c1cc2ccccc2o1 +CC1CCc2nc(CN3CCOCC3C3CC3)sc2C1 +CC1CC2CN(C(=O)CCc3ccc(Cl)cc3)CCC2O1 +COc1ccccc1OCC(=O)NC(C)(C)c1ccc(F)cc1 +Cc1ccc2c(c1)oc(=O)n2CCNC(=O)c1cnc(C)cn1 +O=C(CN1CCc2ccccc21)NCc1ccccc1 +CN(CCC(O)c1ccccc1)C(=O)CCc1n[nH]c2c1CCCC2 +C#CCC(C)OC(=O)c1ccc(CC)c(S(C)(=O)=O)c1 +Cc1cc(C)cc(C(N)C(=O)NCC2CCCO2)c1 +CCC(NC(=O)NCc1sccc1C)C(C)C +CCN(CC)C(=O)CNc1ccc(C(=O)NC)c(Cl)c1 +COCc1ccc(C(=O)Nc2cc(OC)ccc2F)o1 +COC(C)c1noc(COc2cc(Br)ccc2Cl)n1 +CC(C(=O)NCc1cccnc1-n1cnc2ccccc21)n1cccc1 +CCCCNC(=O)C1CCC(C)N(C(=O)c2cc(C(C)=O)c[nH]2)C1 +Nc1cccc(NC(=O)c2ccc3c(c2)CCC3)c1 +CC12CN(C(=O)c3ccco3)CC(C)(CN(C(=O)c3ccco3)C1)C2 +NC(=O)c1cccc(NC(=O)CCc2cccc(Br)c2)c1 +COCCN1CCCC2(CCN(C(=O)c3ccnn3C)C2)C1=O +Cc1cc(C)n(CCOc2ccc3c(c2)CCC(=O)N3)n1 +O=C(N=c1[nH]c2ccccc2[nH]1)C1CN(Cc2ccccc2)CCO1 +CCN1CCC2(CCCN(C(=O)OC(C)(C)C)C2)C1=O +Cc1nn(-c2ccccc2)c(C)c1C(=O)NC1CCCCC1 +CNc1c[nH]c(=NS(C)(=O)=O)cc1OC1CC1 +CCc1nc(Cn2c(=O)c(C)nc3ccccc32)cs1 +COC(=O)C(C)n1cnc2sc3c(c2c1=O)CCC(C)C3 +CCCOC(=O)C1=C(C)Nc2nnnn2C1c1ccc(OCC)cc1 +Cc1cc(C(=O)N2CCN(C(=O)C(C)(C)C)CC2)c(C)n1C1CC1 +COc1ccc(F)cc1C(=O)NCCc1ccccn1 +CCc1cccc(CC)c1NC(=O)COc1ccccc1C#N +CCOC(=O)Nc1cccc(C(=O)OCc2cc(C)on2)c1 +CCn1ccc(=O)c(NC(=O)c2cccc3ncccc23)c1 +CNS(=O)(=O)c1ccc(C(=O)NC(Cc2ccccc2)C2CC2)o1 +COC(=O)Nc1ccc(NC(=O)c2cc(F)c(F)c(F)c2F)cc1 +Cc1cccc(C(=O)Nc2cccc(-c3cnco3)c2)c1 +Cc1ccc(C(=O)CC2(O)C(=O)Nc3ccccc32)c(C)c1 +Oc1ccc(CNc2cc(F)cc(F)c2)cc1F +CCCNC(=O)COC(=O)c1ccc(OC)c(Br)c1 +CN(C)c1ncccc1C(=O)Nc1ccc(F)cc1 +CCOc1ccc(-n2ccnc2SCC(N)=O)cc1 +N#Cc1ccccc1S(=O)(=O)N(Cc1ccco1)CC1CCCO1 +CCN(C)C(=O)c1cccc(OCC(=O)Nc2cc(C)ccc2C)c1 +C#CCNC(=O)CSc1nccn1-c1ccc(C(C)C)cc1 +CCCc1noc(C(C)Nc2ccc(-c3csc(C)n3)cc2)n1 +COC(=O)N(C)c1ccc(NC(=O)NCC2CC2)cc1 +O=C(Nc1cccnc1-n1cncn1)c1ccc(-n2cccc2)c(F)c1 +Fc1ccc(NCc2ccc3c(c2)OCO3)c(F)c1F +COC(=O)c1cccc(-c2nn3c(C(F)(F)F)nnc3s2)c1 +COc1cc(=O)n(-c2ccc(F)cc2)nc1C(=O)NCC(C)C +Fc1ccc(Cn2ccnc2C(F)(F)F)cc1Br +Cc1cc(C(=O)OCC(N)=O)c(C)cc1Br +CCCNC(=O)C1CCCN1S(=O)(=O)c1cccs1 +CCCc1nnc2n1NC(c1ccccc1)CS2 +COc1cc(Cl)c(C)cc1NCc1nc(C(C)C)no1 +CC(=O)c1nc2ccc(F)c(F)c2n1-c1ncccc1C#N +CCOc1ccccc1CCC(=O)N1CCC(C(=O)NC)CC1 +CC(C)(C(=O)N1CCCC(S(N)(=O)=O)C1)c1cccc(F)c1 +O=C(CCc1ncc(-c2ccccc2F)o1)Nc1ccccc1O +CCC(C)NC(=O)Cc1csc(-c2ccc(N)cc2)n1 +Cc1cccc(OCC(=O)Nc2nc(-c3ccccn3)cs2)c1 +CCn1ncnc1C(C)NC(=O)c1cnc(Nc2ccccc2)nc1 +Cc1ccc(C)c(OC(=O)Cn2ccc(=O)n(C)c2=O)c1 +CC(NC(=O)C1CCCCC1)C(O)c1ccccc1 +Cc1cc(C)c(CNC(=O)Nc2cc(C)on2)c(C)c1 +CNC(=O)Cc1ccc(NC(=O)c2ccc(C#N)cc2)cc1 +CC(=O)N1CCc2cc(CNC(=O)Nc3ccc(C)c(F)c3)ccc21 +CC1(C)CN(C(=O)c2n[nH]c3c2CCCC3)CCC1(C)O +Cc1nnc(NC(=O)Cc2coc3cc(C)c(C(C)C)cc23)s1 +Cc1ccc(CCNC(=O)c2[nH]nc3c2CC(C)CC3)o1 +CCN(CCCNc1ccnc(C)n1)S(C)(=O)=O +CC(C)N(CC(N)=O)C(=O)CC1CCN(C(=O)OC(C)(C)C)CC1 +CC(C)(c1ccccc1)c1nnc(-c2cnc3onc(C4CC4)c3c2)o1 +N#Cc1cccc2cccc(S(=O)(=O)N3CCOCC3)c12 +CCNC(=O)C1(NC(=O)COc2ccc(F)cc2F)CCCCC1 +N#CCCN(Cc1cccnc1)C(=O)c1ccccc1Br +O=C(Nc1ccccn1)C1(c2ccccc2)CCC1 +COC(=O)C(C)NC(=O)C(C)c1ccc2cc(OC)ccc2c1 +CCCn1nnnc1CS(=O)(=O)c1nccs1 +COC(=O)CN(C)C(=O)c1nccc2c(N)c(C)ccc12 +CCS(=O)(=O)N(C)Cc1nccn1C(F)F +COc1ccccc1C(=O)Cn1cnc2sccc2c1=O +CCN(CC)C(=O)c1cc(-c2ccc(OC)c(OC)c2)on1 +O=S(Cc1nnnn1C1CC1)c1ncccc1Cl +Cn1cc(CC(=O)Cc2ccccc2Br)cn1 +O=C(c1ccc2c(c1)OCO2)N1CCn2c1nc1ccccc12 +CC(C)CN1CCOC(CNC(=O)c2ccccc2OC(F)F)C1 +Cc1cccc2c1CCN2C(=O)C1CC1c1ccco1 +NC(=O)c1n[nH]c2ccc(NCc3c(Cl)cccc3Cl)cc12 +CCC1COCCN1Cc1c(C)nn(CC(=O)OC(C)C)c1C +Nn1cnnc1SCC(=O)Nc1c(Cl)cccc1Cl +O=C(NC1CCCCCC1)c1nc2ccccc2c(=O)[nH]1 +Cc1cccc(-c2nc(CC(=O)Nc3cn[nH]c3)cs2)c1 +COc1ccccc1CN1C(=O)CCC1(C)C(=O)NCCC(C)C +Cc1cc(C)n(CCN2CCN(C(=O)c3snnc3C)CC2)n1 +Fc1ccc(-c2nnn(Cc3nnc(-c4ccco4)o3)n2)cc1 +CC(NC(N)=O)C(=O)N(Cc1cccnc1)C(C)C +Cc1cc(Cl)ccc1OC(C)C(=O)NCc1cccnc1 +CCOC(=O)c1c(C)c(C(=O)NCc2ccc(F)cc2)c(C)n1CC +CCCn1ncc(C(=O)N2CC3CCCC2C3)c1C +CC(=O)Nc1ccc(Nc2nc(-c3ccncc3)cs2)cc1 +CCOc1cc(C(=O)Nc2nccs2)ccc1OC(F)F +NS(=O)(=O)c1ccc2c(c1)CCN2C(=O)CSc1ccccc1 +CN(C)C(=O)N1CCN(Cc2coc(-c3cccs3)n2)CC1 +COc1cc(-c2nc(CCO)cs2)ccc1O +CCCc1cc(=O)oc2cc(OCC(=O)N3CCNC(=O)C3)ccc12 +CC(CC#N)N(C)Cc1cnc2ccc(C#N)cn12 +CCC1Oc2ccc(N)nc2N(CCC(C)C)C1=O +COc1ccc(C2CC(=O)CC(Nc3nonc3N)C2)c(OC)c1 +Cc1ccc(NC(=O)CCNC(=O)N(C)Cc2ccncc2)nc1 +N#Cc1cnc(COc2ccccc2Cl)nc1N +N#Cc1ccc(-c2noc(Cc3c[nH]c4ccccc34)n2)nc1 +O=C(CCC(=O)c1cccs1)NCC1(O)CCCc2ccccc21 +COC(=O)CSc1nc2sccc2c(=O)n1-c1ccccc1 +N#Cc1ccc(Oc2ncnc3cc(F)c(F)cc23)c(Cl)c1 +Cc1ncsc1C(=O)Nc1ccccc1OCc1cscn1 +Cc1c(C(=O)N(C)C)sc2nc(CC#N)[nH]c(=O)c12 +O=C(COC(=O)c1cccs1)NCc1ccccc1F +CC(C)n1ncc2c(C(=O)NCCCC(N)=O)cc(C3CC3)nc21 +COc1cc(C)c(C(=O)NCCc2ccc(F)cc2C)cc1OC +COc1cccc(OC)c1C(=O)c1ccccc1OC(C)=O +COc1ncnc2c1CCN(C(=O)C1CCCCC1)C2 +CCCNC(=O)c1cc(C)nc2c1c(C)nn2CCC +COc1ccnc(NC(=O)c2ccccc2C#N)c1 +COc1ccc2oc(C(=O)N3CCC(OCC(C)C)CC3)c(C)c2c1 +COc1cccc(CNC(=O)c2ccc(-c3ccsc3)nc2)c1 +COc1ccc(Cl)cc1CNC(=O)COc1ccc(C(C)=O)cc1 +CC(NS(=O)(=O)c1ccc(F)c(F)c1)c1ccccc1 +CC(C)c1ccc(OCc2nnc(SC3CCOC3=O)n2N)cc1 +C1COC(CN(Cc2nnnn2C2CC2)CC2CCCO2)C1 +CCc1cc(OCc2nnnn2C2CC2)ccc1Cl +Cc1ccc(-c2cc(NC(=O)c3ccoc3)on2)s1 +O=C(NCc1ccc(Cn2ccnc2)cc1)C1CCCC1 +COc1ccc(OC)c(C2Cc3ccccc3N2)c1 +O=C(CCC(=O)c1ccc(Br)cc1)NCCO +CCC1C(=O)NCCN1C(=O)c1cccc(COC)c1 +Cc1cc(C(=O)N2CCN(C(=O)CO)CC2)nn1-c1ccccc1 +CCc1nnc(NC(=O)C(C)OCc2ccccc2)s1 +Cn1c(=O)n(C)c2cc(-c3ncc(N)nn3)ccc21 +Cc1nn(C)c(C)c1NC(=O)C(C)Sc1nnnn1C(C)(C)C +Cc1cc(C(=O)N2CCN(c3cc(C#N)ccn3)CC2)on1 +COc1c(Cl)cc(Cl)cc1C(=O)Cn1cccn1 +CC(=O)Nc1cccc(-n2c(SC(C)C)nnc2C2CC2)c1 +Cc1noc(COCC(=O)NC(c2ccc(F)cc2)C(C)(C)C)n1 +COc1ccc(Cl)cc1NCCN1CCNC1=O +CCOC(=O)c1c(C2CC2)csc1NC(=O)c1scnc1C +Cc1ccccc1N1CCN(C(=O)CCc2ccncc2)C(C)C1 +COCC1CCCN(C(=O)C2Cc3cc(F)ccc3O2)C1 +Cc1sc2nc(C3CC3)nc(SCC(=O)NC3CC3)c2c1C +OC(CNCc1cc(F)c(F)c(F)c1)c1ccc(F)cc1 +Cc1cc(C)n(CCC(=O)NCC(C)n2nc(C)cc2C)c(=O)n1 +CCCn1cc(N)cc1C(=O)N(C)CC(O)COC +CCn1ccnc(NC(C)c2ccc(N)cc2)c1=O +Cc1c(C(=O)NC(C)c2ccccc2F)oc2c1C(=O)CCC2 +CCOc1ccc(-c2cc(C#N)nn2CC(=O)OC)cc1 +Cn1ccc(C(=O)NC2CCCc3ccccc32)cc1=O +Cc1ccc(C(=O)N2CCN(S(C)(=O)=O)C2c2ccccc2)cc1 +O=C(Nc1ccc(F)c(F)c1F)c1ncccc1O +COC(=O)c1ccc(Cn2nc(C)c3ccccc3c2=O)cc1 +Cc1c(NC(=O)C2CCCCC2)cccc1S(=O)(=O)NC1CC1 +CCN1CCOc2ccc(NC(=O)c3cccc(OC)c3)cc2C1=O +Cc1ccc(C(=O)NCCOc2cccc(Cl)c2)c(=O)[nH]1 +Nc1cc(C(O)CCNc2ccccc2)ccc1Cl +CC(C)c1noc(CCNS(=O)(=O)c2cccc(Cl)c2F)n1 +COCCCNc1nc(C)nc2sc(C(=O)OC)c(C)c12 +Cc1cccc(Cl)c1NC(=O)Cn1c(C)nc2ccccc2c1=O +CCCN(Cc1cnn(C)c1)C(=O)NCc1csc(C(C)(C)C)n1 +CCOC(=O)CN(CC)S(=O)(=O)c1ccc(C)c(F)c1 +Fc1ccc(NCc2cncnc2)c(F)c1Cl +O=C(c1cccc(F)c1)N1CCC(Nc2cccnc2)C1 +COCC(C)NC(=O)Cn1c(=O)oc2ccccc21 +c1ccc2[nH]c(C3CCCN(c4ncnc5nc[nH]c45)C3)nc2c1 +COCC(NC(=O)c1nnn(-c2cccc(Cl)c2)c1C)C(N)=O +Cn1cnc(CNC(=O)c2cn(C)nc2C(C)(C)C)n1 +Cc1ccc(C)n1-c1nc(CC(=O)NCCC(=O)NC(C)C)cs1 +C#CC(CC)(CC)NC(=O)Cn1cnc2cc(F)ccc2c1=O +NC(=O)c1ccc(CNc2cccc(-c3ccn[nH]3)c2)cc1 +CCn1c(=NC(C)=O)sc2cc(C(=O)OC)ccc21 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1ccc(-n2ccnc2)nc1 +CCOc1ccc(Cl)c(C(=O)Nc2ccncc2)n1 +Cc1ccc(N2CCN(C(=O)COc3cccc(C)c3)CC2=O)cc1 +O=S(=O)(N1CCOCC1)N1CCCC1c1ccccc1 +Cn1cc(C(CC#N)c2ccccc2)c2ccccc21 +Cc1nn(C)c(C)c1C(=O)Nc1ccc(N2CCNC2=O)cc1 +COC(=O)CCN(C)C(=O)CCc1ccc(C)cc1 +COCCNC(=O)COc1ccc(C(C)C)cc1 +NS(=O)(=O)c1cc(C(=O)Nc2ccccc2N2CCCC2)co1 +Cc1cc(C)c2c(c1)NC(=O)C2CC(=O)Nn1cnnc1 +CCOc1ccc(NC(=O)C2CC(=O)N(C)C2)cc1CO +Cc1cc(F)ccc1NC(=O)COc1ccccc1F +Cc1ccc(CCC(=O)N2CCCCCC2)cc1N +O=C(Cc1cn2ccsc2n1)Nc1cc(-c2ccncc2)n[nH]1 +O=C1CCN(c2ccc(Cl)cc2C(F)(F)F)C1=O +CSc1ccc(C)c(C(=O)NC(C)(C)CO)c1 +CCc1nc(C)sc1-c1nnc(NC(C)C)s1 +CN(CCn1ccc2ccccc21)C(=O)CCc1cn2ccccc2n1 +COC(=O)CCCC(=O)Nc1ccc(C(C)=O)cc1 +CC(C)(C)OC(=O)c1ncn2c1C(C)(C)Nc1ccccc1-2 +Cc1ccc(C)c(NC(=O)CSc2nnc(-c3ccccn3)o2)c1 +COC(=O)N(C)CC(=O)Nc1ccc(OC)c(C)c1 +Cc1nc(CNC(=O)C(c2ccccc2)N(C)C)cs1 +COc1ccc(C(O)CNC(=O)c2cccc(C)c2O)cc1 +COc1ccc(S(=O)(=O)Nc2ccc(N3CCCC3=O)cc2)cc1 +CCCC1CN(C(=O)c2cccnc2OC)CCO1 +CNC(=O)C1CCCN1C(=O)CN(C)c1ccccc1 +COc1ccc(CCNC(=O)c2ccnc3ccccc23)cc1OC +O=C(CCc1nc2ccccc2o1)Nc1nccs1 +Cc1ccc(C(O)CNC(=O)c2ccnc(C)n2)cc1 +CCc1nc(C)c(C(=O)N(CC)Cc2c(F)cccc2Cl)o1 +CN(CC#Cc1ccc(Cl)cc1)CC(=O)N1CCC(O)CC1 +CCc1ccc(NC(=O)c2cc3c(=O)n(CC)ccc3n2C)cc1 +CCC1Oc2c(N)cc(C(F)(F)F)cc2NC1=O +CCCn1nc(C(=O)NC2CCCC(C)C2C)ccc1=O +COC(=O)C(C)CN(C(=O)c1cnc(C2CCCO2)s1)C1CC1 +Cc1cc(NC(=O)N2CCCC2c2ccc3c(c2)OCCO3)no1 +CCCN1CCN(C(=O)c2c(C)n[nH]c2N)CC1 +Cc1ccc(-c2noc3ncn(CCC(=O)NC4CC4)c(=O)c23)cc1 +COc1ccc(-n2nnnc2SCCCc2cnn(C)c2)cc1 +O=c1cc(-c2ccccc2)nc2n1CCN2CCCN1CCOCC1 +Cn1cc(CCC(=O)Nc2nc3ccccc3[nH]2)cn1 +CS(=O)(=O)NC1CCCN(C(=O)CCc2ccc(C#N)cc2)C1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1snnc1C +O=C(Nc1nc2c(s1)COCC2)c1ccc(F)cc1Cl +Cc1cc(C(=O)OCC(=O)NC2CCCc3ccccc32)on1 +CCOC(=O)c1c(NC(C)=O)sc2c(NC(C)=O)cccc12 +CC(CNC(=O)c1cc2c([nH]c1=O)CCCC2)c1cccs1 +COCCCNC(=O)c1cc2ccc(OC)cc2[nH]1 +CC(C)Oc1ccc(-c2cn3cccc(N)c3n2)cc1 +COCc1nc(OC)c2c(C)c(C(=O)N3CCCC3)sc2n1 +CCC(C(=O)OC(C)C)N1CC(C)Oc2ccc(N)cc21 +Cc1ccc(-c2nnc(SCCCO)n2C)cc1 +COc1ncccc1CNC(=O)c1ccc(NC(=O)C(C)C)cc1 +Cc1noc(C2CN(C(=O)NCCCc3ccccc3)C2)n1 +C#CCSc1nnc2[nH]c(=O)c3c(n12)CCCC3 +c1ccc(OCCN2CCN(c3nccs3)CC2)cc1 +COc1cc2ncn(CC(=O)Nc3ccc(C#N)cc3)c2cc1OC +CN(C)S(=O)(=O)c1cccc(-c2cc(O)cc(C(F)(F)F)c2)c1 +CCC(=O)NC(Cc1ccccc1)CN(C)C(=O)CC +CC(C)C(=O)N1CCOCC(Oc2ccc(C(F)(F)F)cn2)C1 +O=C(CCc1cnn(-c2ccccc2)c1)N1CCCC1Cn1cccn1 +Cc1ccn2cc(C(=O)N3CCN(c4ccc(F)cc4)CC3)nc2c1 +CN1CCc2nc(C(=O)Nc3ccccc3F)sc2C1 +C=CCOc1cccc(NC(=O)c2cc(C(N)=O)cs2)c1 +Cc1cc(NC(=O)C(C)N2CCOC(c3ccc(F)cc3)C2)no1 +O=C(c1ccc(CO)o1)N1CCC(C(O)Cc2ccccc2)CC1 +CC(=O)Nc1cc(NCc2ccc(Cl)c3cccnc23)ccc1F +COCC(NC(=O)c1sc2ccc(F)cc2c1C)C(N)=O +NC(=O)c1cccc2c1CCCN2Cc1ccccc1 +COc1ccc(Cc2n[nH]c(N3CCCCC3)nc2=O)cc1 +CC(C)(C)OC(=O)CNC(=O)Cc1csc(-c2ccccn2)n1 +Cc1ccc(CCC(=O)C(C#N)c2ccccn2)cc1 +CCCCOc1ccc(C(=O)NCC2(O)CCCC2)cc1 +Cn1cc(C(N)=O)cc1C(=O)OCC(C)(C)c1ccccc1 +CC(C)CCCC(C)NC(=O)c1ncccc1O +COc1ccc(NC(=O)C(C)n2nnc(C#N)c2C)cc1 +CC(=O)OC1CCN(Cc2cnc(C3CCC3)s2)CC1 +O=C(c1cn[nH]n1)N(Cc1ccccc1)Cc1nccs1 +O=C(NC1CCc2ccccc21)N(CCCCO)C1CC1 +Cn1c(C(=O)Nc2ccc(F)c(F)c2F)cc2cc(F)ccc21 +CSc1cccc(NC(=O)NC2CCCC2)c1 +Cc1ccc(CC(=O)NCC2CN3CCCCC3CO2)cc1 +CC(NC(=O)c1ccc2nncn2c1)(C(N)=O)c1cccc(Cl)c1 +CC1CCC(NC(=O)c2cc3ccccc3oc2=O)CC1 +Cc1cccc(NC(=O)CSc2nc3ccccc3c(=O)n2C)c1 +O=C(NCC1CCCO1)NCC1(c2ccc(F)cc2)CCOCC1 +O=C(Nc1cccnc1)N1CCN(C(=O)c2ccccc2O)CC1 +CC(=O)NC(c1ccccn1)C1CCC(CNC(=O)C(C)(C)C)CC1 +CC(=O)Nc1scc(-c2ccc(C)cc2)c1C(N)=O +N#Cc1cccc(CNC(=O)C2CC(=O)N(Cc3ccccn3)C2)c1 +O=S(=O)(c1cccc2nonc12)N1CCNCC1 +Cc1ccc(OCCCC(=O)Nc2nnc(C3CCCO3)s2)cc1 +Cc1cc(NC(=O)C2(C)Oc3cccnc3NC2=O)ccc1F +O=C(Oc1ccc2ccc(=O)oc2c1)c1cccc(-n2cccn2)n1 +CC(c1n[nH]c(=O)n1-c1ccc(F)cc1F)n1cccn1 +CCC(C)NC(=O)CN(CCc1ccccc1)C(C)=O +Cc1cnn(CCC(=O)N2CCC(C(=O)N3CCCCC3)CC2)c1 +CCc1ccc2nc(NC(=O)CCCCNC(N)=O)sc2c1 +CCOC(=O)CCC(=O)c1ccc2c(c1)OCCCO2 +Cc1nc(SCc2noc(-c3cccs3)n2)c2ccccc2n1 +Cc1cc(C)nc(C(C#N)C(=O)Nc2ccccc2)n1 +Cc1cc(C(C)NC(=O)c2cn(-c3ccccc3)nn2)c(C)s1 +O=C(NC1CCN(c2ncccc2F)C1)c1c(F)cccc1Cl +CCc1c(C(=O)N2CCCCC2)cnn1-c1cccc(Cl)c1 +CC(C)C(NC(=O)c1c(F)cccc1F)C(=O)Nc1cc[nH]n1 +O=C(Nc1cccc(F)c1)N1CCOCC1C1CC1 +CCN(CCO)C(=O)c1cc(C2CC2)nc2onc(CC(C)(C)C)c12 +Cc1occc1C(=O)NCC(=O)Nc1nc(C(C)C)cs1 +CC(C)CCNC(=O)CSc1ncccc1C#N +O=C(NCc1ccccc1OC1CCC1)N(CCO)C1CC1 +Cc1cc(C)n(CC(=O)NCC(c2c(F)cccc2F)N(C)C)n1 +COc1cc(C(=O)Nc2ccc(Cl)cc2N)cc(OC)c1OC +Cc1ccc2c(c1F)C(C(=O)c1cccs1)NCC2 +O=C(Nc1nnc(C2CCCCC2)o1)c1ccc(F)cc1F +O=C(CNC(=O)c1ccn(-c2cccc(Cl)c2)n1)NC1CC1 +Cc1ccc(NC(=O)CCNS(=O)(=O)c2ccc(F)cc2)cc1 +CCC(Sc1ccc(NC(=O)c2cccs2)nn1)C(=O)OC +Cc1occc1-c1nnc(CCC(=O)Nc2ccc3ccccc3c2)o1 +Cc1cc(C)n(Cc2cccc(C(=O)Nc3ccc(F)c(C#N)c3)c2)n1 +c1ccc2c(c1)CN(c1nc(C3CC3)ns1)CC2n1cccn1 +COC(=O)c1ccoc1CSc1nc2ccsc2c(=O)n1C +O=C(Nc1nc2c(s1)CCC2)C1CCN(CC(F)(F)F)CC1 +CCOc1cc(NS(=O)(=O)c2cccs2)ccc1OC +Cc1cc(C(=O)NCCc2csc(C)n2)c2c(C)noc2n1 +Cc1cccc(C(=O)OCC(=O)Nc2ccc3c(c2)OCO3)c1N +Cc1nccc(CNC(=O)NCc2ccccc2OCC2CC2)n1 +NS(=O)(=O)NC(c1ccccc1)c1ccccn1 +COc1cc(Cl)c(C)cc1NC(=O)CCCO +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)N(C)C1CCCCC1 +CC(=O)Nc1ccc(F)c(C(=O)NCCc2ccc(F)cc2C)c1 +CCC(=O)Nc1ccc(C)n(CC(=O)NCc2cccc(C)c2)c1=O +Cc1nc(C)c2c(C)c(C(=O)N3CCN(CC(C)O)CC3)sc2n1 +COc1cc(-c2cc(C(=O)OC(C)C)n(C)n2)cc(Cl)c1O +COC(=O)CCC(=O)c1cc(Cl)cc(C)c1OC +CCOC(=O)c1c(C)[nH]c(C(=O)NCc2cccs2)c1C +O=C1CCCc2c1c(C1CC1)nn2-c1ncccn1 +CSc1ncc(CNC(=O)C(c2ccc(C)cc2)N(C)C)n1C +O=C(OCCc1c[nH]nc1C(F)(F)F)c1ccc2c(c1)COC2 +CN(C)C(=O)c1ccc(OCCc2ccccc2)cc1 +c1cnc(N2CCOC3C(OCCN4CCOCC4)CCC32)nc1 +COCc1ccc(CNC(=O)c2cc3c([nH]c2=O)CCCC3)cc1 +CSc1ccc(Cl)c(C(=O)Nc2ccc3c(c2)OCCO3)c1 +COc1cc(NC(=O)COc2cccc(C#N)c2)cc(OC)c1 +O=C(CSc1ccncc1)NC1CCc2c(F)cccc21 +CC(C)c1nc(Cc2ccccc2Br)nn1C +Nc1cc(N)nc(SCc2nc3ccccc3c(=O)[nH]2)n1 +N#Cc1ccc(OS(=O)(=O)c2ccc(F)c(C#N)c2)c(Cl)c1 +NS(=O)(=O)c1ccc(-c2nc3ccccc3[nH]2)cc1 +COc1ccc(F)cc1NC(=O)c1cc(C)ccc1S(N)(=O)=O +CC(c1ccncc1)N(C)C(=O)CNC(=O)CC1CCCCC1 +CCC(=O)NCC(=O)N1CCN(C(=O)C2CCCCC2)CC1 +O=C(COCCc1ccccc1)Oc1ccccc1F +CCCn1cc(NC(=O)c2cc(C)n(C3CC3)c2C)ccc1=O +Cc1cc(NC(=O)CSc2ccc(O)cc2)n(C)n1 +CCC(O)CN1CCN(C(=O)c2nccc3ccccc23)CC1 +CCn1cc(CNC(=O)c2nnc3ccc(C)cc3n2)cn1 +O=C(Nc1ccc(-n2cccn2)cc1)N1CCc2cc(F)ccc2C1 +COC(=O)C1CCCc2nc(-c3ccc(N)cc3)nn21 +Cc1cccc(OCCCC(=O)N(C(C)C)C2CCOCC2)c1 +CN(C(=O)Cn1cnnn1)c1cccc2ncccc12 +COCC(O)CN(C)C(=O)Nc1cc(F)c(OC)c(F)c1 +COC(=O)NCC(=O)NCCC12CC3CC(CC(C3)C1)C2 +Cc1cc(Sc2ccccc2)ccc1NC(=O)NCCO +NC(=O)C1CCN(C(=O)c2ccc(COc3ccccc3)cc2)CC1 +CCOCCC1CCN(c2ccc(-n3nc(C)cc3C)nn2)CC1 +CC(C)CCNC(=O)c1oc2ccccc2c1CSc1ncn[nH]1 +Cc1cccc(OCCCNC(=O)CN2CCOC(C)(C)C2)c1 +Cc1cc(Cl)cc2c(=O)n(C(C)Cc3cccnc3)cnc12 +COc1cc(NCc2ccc(OC)c(OC)c2)ccc1NC(C)=O +NS(=O)(=O)CCNC(=O)c1ccc(C2CCCCC2)cc1 +COc1ccc(-c2noc(CCC(=O)N3CCOC(C)C3)n2)cc1 +COc1ccc(CNC(=O)C(Cc2ccccc2)NC(N)=O)cc1 +O=C(Cn1cccn1)NC(c1ccccc1)c1ccccc1 +CCCSc1ccc(C(=O)CCN2CCOCC2)s1 +Cn1cc(-c2ccncc2)cc1C(=O)NC1CCCCC1 +CCc1ncc2c(n1)CN(C(=O)C(CC)n1cccn1)C2 +O=C(Nc1cccc2ncccc12)c1ccc[nH]c1=O +CCCn1nnc2cc(C(=O)Nc3ccccc3OC)ccc21 +Cn1cnc(-c2ccc(NC(=O)NC3C=CC(CO)C3)cc2)n1 +Cc1ccc(NCc2nnnn2-c2ccccc2)c(F)c1 +NC(=O)c1cc(NC(=O)c2ccc(OCC(F)F)nc2)ccc1F +CCC(=O)N1CCCC(C(=O)Nc2ccc(OC(C)CC)cc2)C1 +CC(C)(C)NC(=O)N1CCc2nc3ccccn3c(=O)c2C1 +Cc1ncsc1C(=O)NC(C)C(=O)NCc1ccco1 +CCN(CC(F)(F)F)S(=O)(=O)c1ccc(F)cc1C +COCCNC(=O)C(C#N)C1C(=O)N(C)c2ccccc21 +COc1ccccc1C(C)NC(=O)C(C)Sc1nc(C)cc(N)n1 +CC(=CC(=O)OCCN1CCCC1=O)c1ccc(F)cc1F +CCN(CCO)C(=O)c1ccc(-n2ccnc2)cc1 +CSc1ccc(CN2CCn3c(nn(C)c3=O)C2)cc1 +O=S(=O)(Nc1nc2c(F)cccc2s1)c1ccccc1 +CCOc1ccc(NC(=O)CNC(=O)c2snnc2CC)cc1 +CCOc1ccc(NC(=O)CCNC(=O)c2ccco2)cc1 +CC(Oc1cccc(Cl)c1Cl)C(=O)N1CCNC(=O)C1 +CC1c2ccsc2CCN1CC(=O)c1c(N)n(C)c(=O)n(C)c1=O +O=C(CNc1ccc(C(=O)N2CCCCC2)cc1)NCc1ccco1 +COc1ccc(C(=O)NCCc2cccc(OC)c2)cc1 +CC(NC(=O)CSc1ccccn1)c1ccccc1Cl +CN(Cc1ncnn1C)C(=O)c1c(F)cccc1Cl +O=C(Nc1cc(F)c(F)c(F)c1)c1cccnc1OCC(F)F +Cc1nc2ncnn2c(C)c1CC(=O)NCc1ccccc1Cl +CC(C)(C)C(=O)CSc1n[nH]c(=O)n1CC1CCCO1 +CN(C)S(=O)(=O)NC(c1ccccc1)c1cccc(F)c1 +COc1ccc(OC)c(CNC(=O)c2c(C)nn(C)c2C)c1 +CCn1nc(C)c(CCNS(=O)(=O)c2ccc(OC)cc2)c1C +CN(C)C(=O)c1ccc(NC(=O)CN(C)c2c(F)cccc2F)cc1 +COC(=O)N1CCC(NC(=O)c2cc3c(s2)CCC3)CC1 +CNC(=O)c1cccc(NC(=O)NCc2cnc(C)s2)c1C +COc1ccc(C(=O)NCc2cccnc2Oc2ccc(C)nc2)cc1 +Cc1cc(NCCc2c[nH]c3ccccc23)cc(=O)[nH]1 +COc1ccc(F)cc1-c1c(C)sc2c(=O)[nH]c(C)nc12 +Cc1ccc(CC(C)NC(=O)Nc2ccccn2)c(C)c1 +N#Cc1cccn2nc(-c3ccccc3Cl)nc12 +CC(C(=O)NC1CC1)n1nnc(-c2ccccc2)n1 +CCCOC(=O)c1ccc(NCC(=O)N2CCOCC2)cc1 +COC(=O)C(C)Sc1nnc(C(F)(F)F)n1N +COC(=O)CCCn1c(C(C)C)nc2cc(N)ccc21 +Cc1ccc(OCC(=O)NCc2ccc(C)nc2)cc1 +Cc1cccc(OCCNS(=O)(=O)C(C)C)c1 +O=C(Nc1nnc(C2CC2)s1)c1cc(F)ccc1N1CCOCC1 +CCc1nc2sc(=Cc3cc(Cl)ccc3OC(C)=O)c(=O)n2n1 +NC(=O)OCCNC(=O)c1cc(F)c(Cl)cc1F +Cc1nc(CN(C)Cc2ccccc2OC(F)(F)F)cs1 +CC(C)CCCNC(=O)c1ccccc1S(C)(=O)=O +CC(CO)NC(=O)c1cc(Br)cn1C +Cc1nc2nc(N)nn2c(C)c1CCC(=O)NC1CCCCC1C +CC(C)CC(=O)Nc1ccc(C(=O)Nc2nccn(C)c2=O)cc1F +CS(=O)(=O)N1CCCC(C(=O)N=c2[nH]c3ccccc3[nH]2)C1 +Cc1cc(S(=O)(=O)N2CCN(CC(=O)N(C)C)CC2)c(C)s1 +Cc1noc(C(C)C)c1C(=O)NC(C)c1ccc2c(c1)OCCCO2 +CC(C(=O)N1CCCC1)N1CCN(C(C)c2cccc(Cl)c2)CC1 +CN(Cc1cccs1)c1cc(=O)n2cc(Cl)ccc2n1 +CN(C)c1cccc(OCCc2ccc(CO)cc2)c1 +CN(C)c1nc2c(c(N)nn2-c2ccccc2)c(=O)o1 +CCC(Sc1ncnc2sc(C)cc12)C(=O)N1CCNCC1 +CC1CCC(C)N(C(=O)Nc2ccc3c(c2)oc(=O)n3C)C1 +CCC(C)NC(=O)NCc1cccn1Cc1ccc(F)cc1 +COc1cccc(C(=O)NCc2cc3ccccc3[nH]2)c1F +Cc1csc2ncc(C(=O)Nc3ccncc3)c(=O)n12 +N#Cc1ccc(C(=O)NCc2n[nH]c3ccccc23)cc1 +COc1ccc(CNC(=O)c2ccccc2-n2nnnc2C)cc1 +CCCCN(CC)C(=O)Cc1ccc2c(c1)OCCO2 +Cc1n[nH]c(C)c1NC(=O)c1ccc2cc[nH]c2c1 +N#Cc1c(N)nsc1Nc1ccc(Cl)cc1 +O=C(c1ccno1)N1CCN(c2cc(-c3ccccc3)ncn2)CC1 +Cc1noc(NC(=O)Cn2c(=O)cnc3ccccc32)n1 +CCCOc1ccc(NC(=O)c2cccc(F)c2N)cc1 +COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)c1ccoc1C +O=C(Nc1ccc(-n2cncn2)nc1)N1CCC2CCCCC2C1 +Cc1cccc(NC(=O)C(C)Sc2nc(N)cc(N)n2)c1C +CN(CCCOc1cccc(S(C)(=O)=O)c1)C(=O)c1ccc[nH]1 +CCN(Cc1ccc(OC)c(F)c1)C(=O)c1cnc2onc(C)c2c1 +CCOCCCNC(=O)Nc1ccc(C)c(C(F)(F)F)c1 +CCCCCC(=O)NC1CCCN(Cc2ccccc2)C1=O +CCOCc1ccccc1CNC(=O)c1cn(C)c2ccccc12 +O=C(NCCC(=O)N1CCCC1)Nc1cc(F)ccc1Cl +Cc1cccc(NC(=O)Cn2cnc(-c3ccc(F)cc3)cc2=O)n1 +O=S(=O)(Nc1cn[nH]c1)c1c(Cl)cccc1C(F)(F)F +COC(=O)CC1CCCCN1C(=O)Cn1cncn1 +O=C(NCCSc1ccccc1)Nc1ccncc1 +CCCn1c(CNC(C)(C)C(=O)OC)nc2ccccc21 +O=C(NCC(O)c1ccoc1)c1cc(=O)c2ccccc2o1 +CCCn1nc(C(=O)NCc2ccccc2OC)ccc1=O +CN1CCN(S(=O)(=O)c2ccc(F)c(Cl)c2)CC1 +N#Cc1ccc(CCC(=O)OCc2nnc(-c3cccs3)o2)cc1 +CSc1cccc2sc(N3CCN(C(=O)C4CC4)CC3)nc12 +O=C(Nc1ncccn1)c1ccccc1Br +Cc1noc(C)c1C(C)NC(=O)Nc1cc(-c2ccccc2)on1 +O=C1CCC(C(=O)NCCc2ccc3c(c2)OCO3)N1 +COC(=O)c1cc(NCC(=O)N2CC(C)OC(C)C2)ccc1Cl +C=CCCCN(C)C(=O)c1sccc1S(=O)(=O)N(C)C +COc1cccc(COC(C)C(=O)Nc2ccc(F)c(F)c2F)c1 +COc1cccc(N2Cc3c(N)cccc3C2=O)c1 +CCC(=O)N1CCN(c2nc(C)cc(N3CCCCC3)n2)CC1 +O=C(NCCNC(=O)c1ccco1)c1cc2sccn2c1 +COC(=O)CCC(=O)Nc1ccccc1Oc1ccccc1 +CCCS(=O)(=O)N1CCC(NC(=O)Nc2ccc(F)cc2)CC1 +O=C(Nc1ccc(F)cc1F)c1nc(-c2cnccn2)no1 +Cc1cccc(Cl)c1NC(=O)c1ccc(C(=O)N(C)C)cc1 +CCOC(=O)c1sc2nc(C)[nH]c(=O)c2c1C +COc1ccc(-c2nnc(Cn3cnc4cc(F)c(F)cc43)o2)cc1 +O=C(NC1CCCC1)c1cn(-c2ccccc2)nc1-c1cccnc1 +Cn1ncc2c(NCCO)nc(NC3CCCC3)nc21 +CCc1ccccc1NS(=O)(=O)c1ccc2[nH]c(=O)ccc2c1 +CCC(OC1CCCCC1)C(=O)Nc1cnn(CC(F)(F)F)c1 +Cc1nnc(CNC(=O)C2CC(=O)N(C(C)(C)C)C2)o1 +C=CCN(Cc1nccn1Cc1ccccc1)C(C)=O +O=C(CN1CCN(c2ccccc2)C1=O)NCc1cccnc1 +CC1CCCCN1C(=O)CSc1nnc(N2CCCC2)s1 +CC(O)(CNC(=O)Cc1ccc(O)cc1Cl)c1ccc(F)cc1 +Cn1cc(Cl)cc1C(=O)N1CCC(Cc2cccc(CO)c2)C1 +Cn1c(C(=O)N2CCN(S(C)(=O)=O)CC2)cc2occc21 +CCOc1ccc(F)cc1C(=O)CCC(=O)OC +CC(=O)NC(C(=O)Oc1cccc(Br)c1)C(C)C +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1cc(Br)c[nH]1 +O=C(Cn1cnc2sc3c(c2c1=O)CCC3)N1CCCCCC1 +Cc1cccc(NC(=O)Cn2c(=O)c(C)nc3ccccc32)c1C +Cc1ccc(-c2n[nH]c3c2C(c2cccc(O)c2)NC3=O)cc1 +C#CCN1CCN(C(=O)NC2CCN(C(C)=O)C2)CC1 +Cc1ocnc1C(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +O=C1NCCOC2CN(C(=O)Cc3ccc(F)cc3)CCC12 +Cc1ccc(C2NCCc3ccc(C(F)(F)F)cc32)cn1 +COc1cccc2c1C(c1cccc(C#N)c1)NCC2 +CC(C#N)CN(C)C(=O)Nc1nnc(C2CC2)s1 +CC1CN(Cc2n[nH]c(=O)[nH]2)CCN1Cc1n[nH]c(=O)[nH]1 +CCC1(CC)C(NC(=O)c2cc[nH]n2)CC1OC +Nc1ccc(C(=O)OCC(=O)N2CCCCCC2)cc1 +O=C1CCCc2[nH]c(=O)c(C(=O)NCCCc3ccccc3)cc21 +CCC(OC)C(=O)Nc1ccc(N(C)C(C)=O)cc1 +Cc1ccc(CC(=O)N2CCN(C(=O)C3CCCO3)CC2)cn1 +Cc1n[nH]c2ncc(C(=O)NCCCCN3CCOCC3)cc12 +Cc1c(C(C)NC(=O)C2(CO)CC2)cnn1-c1cccc2ccccc12 +COc1cccc2c1N(S(=O)(=O)c1cccc(C#N)c1)CCC2 +CCOc1ncccc1CNC(=O)NCc1ccco1 +NC(=O)c1ccc(NC(=O)c2ccc(N3CCOCC3)nc2)cc1 +CC(Oc1ccc(F)c(F)c1)C(=O)N1CCOCC1C1CC1 +O=C(CCNC(=O)c1cccn2cncc12)NC1CCCCC1 +Cc1cccc(=O)n1CCCCNC(=O)c1c(F)cc(F)cc1F +COc1ccc(C(=O)N(Cc2ccsc2)C2CC2)c(OC)c1 +CCCn1c(C)cc(C(=O)COc2ccc3ccc(=O)oc3c2)c1C +O=C(Nc1nccs1)C1CCCN1C(=O)c1cc2cccnn2n1 +c1ccc2c(c1)CCC21CN(Cc2ccc(-n3cncn3)cc2)CCO1 +COCCN(C)C(=O)Nc1cccc(Cl)c1Cl +COc1ccc(-c2cc(C3(C(=O)NCC(N)=O)CC3)no2)cc1OC +CCCOc1ncccc1CNC(=O)c1ccc(F)c(C)c1 +c1coc(CNc2ccccc2OCC2CCCO2)c1 +O=C(Nc1cc(-n2cnnn2)ccc1Cl)C1COCCO1 +Cc1nc(-c2nc[nH]n2)sc1C(=O)NC1(c2ccccc2)CC1 +Cc1ccc2c(c1)CCCN2Cc1nnc(C)n1C +CC(C)n1nc(C(=O)N2CCNC(=O)C2)c2ccccc2c1=O +CC(CO)NC(=O)c1ccc(NCc2ccccc2)cc1 +O=C(Nc1ccc(Cl)cn1)c1sccc1Br +Cc1ccc(Nc2ncnc(NCC3CCCO3)c2N)nc1 +O=C(C1CC1)N1CCCCCC1c1noc(-c2ccccc2)n1 +CCOC(=O)CCC(C)NC(=O)c1ccc2c(c1)nc(C)n2C +COC(=O)c1cc(OC(=O)c2cccs2)n(C)n1 +Cc1noc(COCC(=O)N2CCCCC2CCc2ccccc2)n1 +CN(C)C(=O)c1ccc(N(C)C)c(NC(=O)c2ccccc2)c1 +COc1ccc(CNC(=O)c2csc(-c3ncccn3)n2)cc1O +CC1CCCN(C(=O)Nc2cc(C(=O)N(C)C)ccc2F)C1CO +Cc1ccc(NC(=O)CSc2nnc3n2CCCCC3)cc1C +Cc1cc(NC(=O)CNC(=O)NCc2ccc(F)cc2)n(C)n1 +Nc1ccc2nc(-c3ccc4oc(=O)[nH]c4c3)cn2c1 +Cc1cc(C(F)(F)F)nc2c(Cl)c(C3CC3)nn12 +OC(CNc1cc(F)c(F)cc1F)c1cccs1 +Cc1nc(CNC(=O)CNC(=O)c2cc3c(s2)CCCC3)cs1 +O=C(CC(F)(F)F)N1CCC2(CCCNC2=O)C1 +Cc1nnc2c(NC(=O)CCCc3ccccc3)cccn12 +CC1CN(C(=O)c2ccc(Br)cc2F)CCO1 +Cc1ccn2c(=O)c(C(=O)NCc3ccc4c(c3)OCO4)cnc2c1 +Cc1csc2nc(-c3cc(F)cc(F)c3)[nH]c(=O)c12 +Cc1cc(C(=O)OC(C)C(=O)Nc2ccccc2)c(C)o1 +O=C1c2oc3ccccc3c(=O)c2C(c2ccccc2)N1CCO +C=CCn1c(NCc2ccc(OC)cc2)nc2c1c(=O)[nH]c(=O)n2C +CC(C)c1noc(CCC(=O)Nc2ccc(Cn3cccn3)cc2)n1 +CCCCc1noc(CSc2nccn2C)n1 +CCNC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCCCCC2)c1 +CCc1onc(C)c1NC(=O)CNC(=O)CCc1ccc(C)cc1 +Fc1ccc(CSc2ncn[nH]2)c2ncccc12 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccc(N(C)C)cc2)cc1 +CCC1(CC)CNc2cc(S(=O)(=O)CC)ccc2O1 +CC(C)NC(=O)Nc1ccc(Oc2cccc(F)c2)nc1 +CC(=O)c1ccc(NS(=O)(=O)c2cccc(C(F)(F)F)c2)cc1 +N#Cc1c(COC(=O)C2COc3ccccc3O2)cn2ccccc12 +NC(=O)c1cnn(-c2ccccc2)c1NCc1ccncc1 +CC(=O)c1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 +CC(COc1ccc2ccccc2c1CO)C(N)=O +NC(=O)COC(=O)CCNC(=O)c1cc(F)ccc1Br +Cc1cccc(-c2noc(C(=O)N3CCN(C)CC3)c2N)c1 +CC(=O)c1cccc(NC(=O)CCS(=O)(=O)c2ccc(C)cc2)c1 +C=C(C)Cn1c(=O)c2c(nc3n(CC(C)C)c(C)cn23)n(C)c1=O +COc1ccc(F)cc1NC(=O)NCCCc1cnn(C)c1 +CNC(=O)CN(c1cccc(C)c1)S(C)(=O)=O +Cc1cc(=O)[nH]c(-c2cccc(OC(=O)c3ccco3)c2)n1 +CCn1nc(C)cc1NC(=O)Cc1ccc(Br)cc1 +CC(=O)c1c(F)cccc1N1CCN(C(=O)OC(C)(C)C)CC1 +COc1ccccc1CCC(=O)Nc1cccc2cn[nH]c12 +Nc1cccc2c1CN(c1ccc(Cl)c(Cl)c1)C2=O +COC(=O)c1cc2nc(-c3ccc(F)cc3)cc(C)n2n1 +COC12C=CC(CC1)c1c2c(O)c2ccncc2c1O +CCc1noc(C)c1C(=O)OCc1nc2c(C)cccc2c(=O)[nH]1 +COc1cc[nH]c(=NS(=O)(=O)c2ccc(F)cc2F)c1 +CNC(=O)c1ccsc1NC(=O)c1cccc(Cl)c1 +CN(CC1CCCCC1)C(=O)c1cnc2ccccn2c1=O +Cc1cccc(C)c1NC(=O)c1csc(Nc2cccnc2)n1 +Cc1nn(CC(=O)N2CCc3cc(F)ccc3C2)c(C)c1Cl +N#CC(CCSc1ccccc1F)NC1CC1 +O=C(Nc1ccc(NC(=O)C2CCCO2)cc1)c1ccccc1F +CN(C)C(=O)CCc1nc(-c2ccc(Cl)cc2)no1 +COC(=O)NCC(=O)Nc1cc(C(N)=O)ccc1C +O=C(NCCNC(=O)c1cccnc1)NCc1ccccc1F +CCc1ccccc1NC(=O)N(C)Cc1ccc(O)cc1 +C=CCNC(=O)c1ccccc1NCc1cccc(F)c1 +Cc1cc(-c2nc3c4c5c(sc4ncn3n2)CCC5)n(C)n1 +Cc1cc(C(=O)Nc2n[nH]c(-c3ccccc3Cl)n2)no1 +N#CCCN(c1c(F)c(F)c(F)c(F)c1F)C1CC1 +OC(CSc1nc2ncccn2n1)c1ccccc1F +CC1(C)CN(C(=O)c2ccc(-n3ccnn3)cc2)C1(C)C +Cc1cc(F)c2c(c1)CCCN2C(=O)Cc1csc(C)n1 +Cc1cccnc1NC(=O)c1cc(Cl)ccc1N +CCCn1c(CNC(=O)c2cccc(C)c2)nc2ccccc21 +Cc1csc(=O)n1CC(=O)N1CCc2cc(F)ccc2C1 +CCC(C)N(Cc1cccnc1)C(=O)c1cncc(C)c1 +CC(=O)NCC1CCCN(C(=O)NCCCN(C)c2ccccc2)C1 +COC(=O)c1ccc(CCC(=O)Oc2ccc3cn[nH]c3c2)cc1 +CCC(=O)Nc1cccc(C(=O)Nc2sc(C)c(C)c2C(N)=O)c1 +CN(Cc1ccc(O)cc1)C(=O)CCn1c(=O)oc2ccccc21 +O=C(Cn1c2c(sc1=O)CCCCC2)NC1CC1 +CC(C)CCN(CCC#N)C(=O)c1nccc2ccccc12 +CN(CC1CC1)C(=O)COc1ccc(Cl)cc1 +CCn1c(SCc2cc(C)on2)nc2ccccc21 +COC(=O)C(C)n1c(-c2cccc(N)c2)nc2ccccc21 +CCCNC(=O)Cn1c(-c2cccc(N)c2)csc1=O +COC(=O)NCCOC(=O)CC1CC2CCC1C2 +CCC1CCC(NC(=O)Cc2csc(N3CCNC3=O)n2)CC1 +CCN(Cc1ccoc1)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +Cc1csc(C2CCCCN2C(=O)COc2ccccc2F)n1 +N#CC1(NC(=O)COc2ccc(-c3nnco3)cc2)CCCC1 +CC(C)(C)c1ccc2cc(C(=O)OCC(N)=O)[nH]c2c1 +Cc1ccc(CCNCc2ccc(S(C)=O)cc2)cc1 +CC(C)(C)c1noc(CCCC(=O)Nc2ccc(F)c(C(N)=O)c2)n1 +COc1cc2c(cc1OC)C(c1ccccn1)NCC2 +COc1ccc(OCC(=O)N2CCC(CO)C2)cc1 +CS(=O)(=O)N1CCCC1CCc1cccnc1-n1ccnc1 +Cc1cc(CN(C)C(=O)Nc2ccc(-c3csc(C)n3)cc2)no1 +CSc1ccc(OC(C)C(=O)OC(C)c2nc(C)no2)cc1 +COc1ccccc1OCCN(C)Cc1cccnc1C +CCN(CC)C(=O)NCc1ccnc(OC(C)(C)C)c1 +CNc1nc(-c2c(COC)oc(C)c2C)cs1 +CC(C)NC(=O)N1CCN(C2CC2)CC1c1ccccc1 +CN1C(=O)Cc2ccccc2C1C(=O)NC1CCCCCC1 +CCCS(=O)(=O)c1ccccc1C(=O)NCCc1cccc(C)c1 +CCn1ncc(NC(=O)Cn2cc(C)c(-c3ccccc3F)n2)n1 +Nc1nc2c(ncn2CCC(CO)CO)c(=O)[nH]1 +COC(=O)c1cc(C(=O)NC2CCCCC2)ccc1F +COc1ccc(Oc2ncnc(NCC3CCCO3)c2N)cc1 +Cc1ccc(Cl)cc1NC(=O)c1cccc(S(C)(=O)=O)c1 +N#Cc1ccc(-c2noc(CCc3nnc(C4CCCC4)o3)n2)nc1 +CCCNC(=O)c1cccnc1SCc1c(C)noc1C +Cc1noc(CCCC(=O)Nc2ccc(OC(C)C)cc2)n1 +Cc1ccc2ncc(C(=O)Nc3cnn(-c4ncccn4)c3)n2c1 +COCCNC(=O)C1CCN(c2nc3c(F)cccc3s2)CC1 +CC1CC(NC(=O)c2c(O)cc(F)cc2F)CC(C)O1 +Cc1c(C(=O)N2CC(C(N)=O)CCC2C)cnn1C(C)(C)C +CCC(=O)NCC1CCN(C(=O)c2cc3ccccc3o2)CC1 +COC(=O)c1ccc(Cn2nnc(-c3ccncc3)n2)cc1 +COc1cc(NC(=O)C(O)c2ccccc2)cc(OC)c1 +O=C(CSc1ccccc1Cl)NCc1ccc2c(c1)OCO2 +CCCn1nnnc1CSc1nncn1-c1ccccc1C +CN1CC(NC(=O)c2cnc(C3CCCO3)s2)CCC1=O +O=C(NCC1CCCO1)c1cncc(-c2ccc(Cl)cc2)c1 +O=C(c1ccccc1Cl)N1CCC(c2nnc(C3CC3)s2)CC1 +O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1ccccn1 +CN(C(=O)C1CCc2ccccc21)c1ccc(Br)cn1 +O=C(CCC(=O)NC1CCCCC1)Nc1noc2ccccc12 +Cc1ccc(C(C)NC(=O)Nc2cnn(C)c2)cc1F +O=C(NCC1(O)CCCC1)c1ccc2ncsc2c1 +CCOC(=O)CC(C)CNC(=O)c1scnc1C +Cc1ccc(CCNC(=O)Cc2cccc(OCC#N)c2)cc1 +CC(C)NC(=O)Nc1cccc(C(=O)NCc2cccc(CO)c2)c1 +COC(=O)c1[nH]c(C)c(CN(C)C(=O)c2ccc(Cl)cc2)c1C +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1c(F)cccc1F +N#Cc1cccc(CNCC2(c3ccc(F)cc3)CCOCC2)c1 +C=CCNS(=O)(=O)c1cc(C(=O)NC(C)CO)ccc1F +Cc1noc(C)c1CNC(=O)c1nc(-c2cccs2)no1 +COC(=O)c1cc(C)nc2onc(-c3ccc(OC)cc3)c12 +COc1cccc(-c2cc(C(=O)Nc3ccc(F)c(F)c3)n(C)n2)c1 +CCC(C(=O)Nc1cc(F)c(F)c(F)c1)c1c(C)noc1C +COCC(Nc1nccn2cnnc12)c1cccc(C(F)(F)F)c1 +COc1cccc(NC(=O)c2nccc3c(N)cc(F)cc23)c1 +CCOC(=O)C(C)(N)Cc1ccccc1C(F)(F)F +CCc1ccc(C(=O)Nc2ccc(S(=O)(=O)NC3CC3)cc2)cc1 +O=C(OC1CCCCC1=O)C1CCCN(C(=O)Cc2ccccc2)C1 +COC(=O)c1ccccc1N(C)C(=O)c1ccoc1 +CC1CCC(C)(NC(=O)c2cccc3c2OCC(=O)N3)CC1 +CCOCCOC(=O)Cn1c(N)nc2cc(Cl)ccc21 +Cc1ccc(C)c2c1CCNC2c1ccc[nH]c1=O +CC(NC(=O)Cn1c(=O)n(C)c2ccccc21)C(=O)N1CCCCC1 +C=CCn1c(C2CC2)nnc1S(=O)(=O)Cc1sc(C)nc1C +Cc1ccc(F)c(OCC(=O)N2CCC(C(N)=O)c3ccccc32)c1 +CCCNC(=O)CSc1ccc(-c2ccc3c(c2)OCO3)nn1 +CN(C)c1ccc(NC(=O)CN2C(=O)CSc3ccccc32)cn1 +Cn1ncc(N2CCOC(CCNC(=O)N3CCCC3)C2)cc1=O +O=C(CCSc1ccccn1)N1CCOc2ncccc21 +Brc1ccc(-c2nc3c4c(ncn3n2)CCC4)cc1 +Cc1ccc(N)cc1NC(=O)COc1cccc(C#N)c1 +CNC(=O)COC(=O)c1sc(NC(=O)c2ccco2)cc1C +Cc1ccccc1C1(CNC(=O)Cn2cnnn2)CCOCC1 +Cc1nn(C)cc1CNc1ccn(-c2ncccc2Cl)n1 +NC(=O)c1cn(CC(=O)NCc2ccccc2)nc1-c1ccccc1 +O=C(OCC1OC=CC(O)C1O)c1ccccc1 +CCc1ccc(C(=O)N(CC)Cc2nc3ccccc3c(=O)[nH]2)o1 +COC1CCCC(C(=O)N2CCCC2c2nc3ccccc3[nH]2)C1 +COc1ccccc1NC(=O)CCS(=O)(=O)c1ccccc1 +Cc1nnnn1-c1ccc(CC(=O)NC(C)C2=CCCCC2)cc1 +O=C(NCCN1CCOCC1)N(Cc1ccccc1)Cc1ccco1 +NC(=O)C1CCCN(C(=O)c2ccc(NC(=O)c3ccco3)s2)C1 +CC(C)CN(CCC#N)S(=O)(=O)c1cnc(N)nc1 +Cn1cnc(CNC(=O)N2CCc3c(Cl)cccc32)n1 +O=C(CN1CCN(c2ncccn2)CC1)N1CCCc2ccccc21 +COc1cc(N2CCC(c3cc(-c4ccco4)n[nH]3)CC2)ncn1 +Cc1cccc2cc3c(N)c(C(N)=O)sc3nc12 +CCOCC1c2c(ncn2C)CCN1S(=O)(=O)c1cccc(C)c1 +N#Cc1cccc(OCC(=O)N2CC(C(N)=O)Oc3ccccc32)c1 +Cc1ccc(-n2ccc3ncc4c(=O)n(C)ccc4c3c2=O)cc1 +Cn1nc(C(=O)NCc2cccs2)c(=O)c2cc(Cl)ccc21 +NC(=O)C1CCN(c2ccc(Cl)cc2N)CC1 +Cc1ccc(-n2nc(C)c(C(=O)N3CCCCC3)n2)cc1 +Cn1c(C(F)(F)F)nn(CC(=O)N2CCOCC2)c1=O +CCCOc1ccc(C(C)NC(=O)c2cc(C)n[nH]2)cc1OC +CCCCC(=O)Nc1nc2cc(OC)c(OC)cc2s1 +Nc1ccccc1C(=O)Nc1ccc2c(c1)OC(F)(F)O2 +CS(=O)(=O)N1CCc2c(CNc3ncccn3)cncc2C1 +CC(=O)Nc1cccc(NC(=O)Cc2ccccc2C)c1C +CC(C)(C)OC(=O)NCC1NCCc2ccc(F)cc21 +Cc1ccc(C(C)N(C)Cc2cc(=O)n3nc(C)sc3n2)cc1 +c1ccc(COC2CCC3C2OCCN3Cc2ccco2)nc1 +CC(C)c1ccc(OCCNS(N)(=O)=O)cc1 +Cc1cccc(-c2c(-c3ccccc3)ncn2C(CO)CO)n1 +Cc1occc1C(=O)N1CCC2(CCC(C(=O)NCC3CC3)O2)CC1 +COC(=O)c1sccc1S(=O)(=O)NCc1ccccc1C +NC(=O)NCc1ccc(NC(=O)C2(c3ccccc3)CC2)cc1 +O=C(Cc1ccc(Cl)cc1)NCCC(=O)N1CCCC1 +CC(=O)Nc1ccc(NC(=O)Cn2cnnn2)cc1 +CCN(CC)S(=O)(=O)c1ccc(SC)cc1 +Cc1ccc(C(O)CCC(=O)N2CCc3ccccc3C2)cc1 +CCN(CC1CCOC1)S(=O)(=O)Cc1ccccc1Cl +Cc1[nH]nc2c1NC(c1ccc(Cl)cc1)NC2=O +CC(C)C(NC(=O)Cc1ccc(F)cc1F)c1nc(C2CC2)no1 +COc1c(C)cc(C(=O)C2CCCN(C(=O)CCC(N)=O)C2)cc1C +CC1CCCN(C(=O)Nc2ccc(F)cc2C(F)(F)F)C1CO +CNC(=O)c1ccc(OCc2cccc(F)c2)c(N)c1 +CCN1CC(C(=O)NCCCn2ccnn2)CCC1=O +CCCc1nc(NCc2ccc3nonc3c2)c2cnn(C)c2n1 +COc1cccc(C(=O)NC(C)c2cc3c(cc2Cl)OCCO3)c1 +Cc1cccc(N2CC(C)Cn3c2nc2c3c(=O)[nH]c(=O)n2C)c1 +COC(=O)c1ccc(S(=O)(=O)N2CCCc3sccc3C2)o1 +Cc1cc(F)ccc1CCNC(=O)NCC(=O)N1CCCC1 +COc1cccc2c1N(Cc1nnc(C3CCC3)o1)CCC2 +O=C(Nc1ccccc1C#Cc1ccccc1)N(CCO)CCCO +O=C(NC1CCc2cc(Cl)ccc21)c1ccncc1 +Cc1cc(C2CCCN2C(=O)c2cc(C3CC3)[nH]n2)no1 +CCC(CC)N(C)S(=O)(=O)c1ccc(C#N)cc1 +CCC(CC)C(=O)N(C)C(C#N)c1ccc(OC)cc1 +CCCCOc1ccc(-c2[nH]nc(C)c2CO)cc1 +CCSc1nnc(N)n1C(CC)C(=O)Nc1ccc(C)c(C)c1 +COc1ccccc1C(NC(=O)OC(C)(C)C)c1ccccn1 +COc1ccc(CNC(=O)Cn2c(=O)[nH]c3ccccc32)cc1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)c1ccc(C(N)=O)cc1 +COc1ccc(C(=O)OCc2nc(-c3ccc(C)cc3)no2)cn1 +CN(C(=O)Cn1nc(-c2ccccc2)oc1=O)C1CCCC1 +CC(C)(C)n1cc(C(=O)N2CCN(Cc3ccncc3)CC2)cn1 +CC(C)n1ccc2c(C(=O)Nc3ccc4c(c3)OCCO4)cccc21 +N#Cc1ccc(Nc2ccc3c(c2)OCCCO3)nc1 +CC(C#N)N1CCC(C(=O)NCc2cccs2)CC1 +COc1ccc(Cl)cc1S(=O)(=O)NCC(O)c1cccs1 +CCSc1nnc(SCC(=O)C(C)(C)C)s1 +O=C(NCCOc1ccc(Cl)cc1)c1ccc2cncn2c1 +Cc1n[nH]c(C)c1CNC(=O)c1c(F)cccc1Cl +COc1ccc(S(=O)(=O)NCc2cccs2)c(C)c1C +CN(C)C(=O)c1ccc(C#CCNS(C)(=O)=O)cc1 +O=C(CCSc1ccccn1)Oc1ccccc1 +Cc1noc(C)c1CN(C)C(=O)C(OC1CCCC1)c1ccccc1 +Cc1nc(C(C)n2ccnc2-c2ccncc2)cs1 +CC(CC#N)N1CCN(C(=O)c2cccc(Cl)c2Cl)CC1 +CCN(CC)C(=O)c1cc(-c2cccnc2)nc2ccccc12 +NC(=O)C1CCN(c2nc(-c3ccncc3)nc3ccccc23)C1 +COc1ccc(C)nc1NC(=O)N1CCCC1c1ccncc1 +CC(COc1ccc(F)cc1)NC(=O)N1CCC(C)C(O)C1 +CC(=O)c1cccc(NC(=O)Nc2cccc3nonc23)c1 +C#CCN(C(=O)CCC(=O)N(CC)CC)c1nccs1 +Cc1nc(Cc2noc(-c3cnc(-c4ccsc4)s3)n2)no1 +N#Cc1ccc(-c2noc(C3CC3c3ccccc3)n2)nc1 +Nc1occ(-c2ccncc2)c1C(=O)c1cscn1 +NC(=O)CC1(NS(=O)(=O)c2c(F)cccc2F)CCOCC1 +CCn1cc(CC(=O)N(CCO)C2CC2)c2ccccc21 +O=C(NCCN1CCOCC1)c1cccnc1Sc1ccccc1 +O=C(c1cc(Br)c[nH]1)N1CCCC1c1ccccc1 +Cc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c(C)c1 +CC1CN(C(=O)CN2CCc3cc(F)ccc3C2)CC(C)O1 +CCc1nc(C2CCCN(C(=O)c3ccc(C)[nH]c3=O)C2)no1 +O=C(c1cccnc1)N1CCN(Cc2ccc3c(c2)OCCO3)CC1 +CCn1ccc(CNC(=O)c2cc(-c3ccccc3)on2)n1 +CCOC(=O)Cc1csc(NC(=O)CC(C)(C)C)n1 +CC(C)CN1C(=O)COC2CN(C(=O)C3CCOCC3)CC21 +Cc1cc(OCC(=O)Oc2cccc(-n3cnnn3)c2)ccc1Cl +O=C(NCc1cn2ccccc2n1)c1ccncc1 +CC1CN(Cc2cnc3ccc(C#N)cn23)C(c2ccccc2)CO1 +CC(c1ccco1)N(C)C(=O)Cc1ccc(F)c(F)c1 +COc1ccc(NC(=O)c2ccc(N(C)C)cc2)c(OC)c1 +CC(C(=O)N1CCN(c2oc(C3CC3)nc2C#N)CC1)n1ccnc1 +Cc1ccccc1-c1nnc(S(=O)(=O)CCCc2cn[nH]c2)n1C +Cc1ccc2nc(NC(=O)CCn3cc(C)cn3)sc2c1 +Cc1sc2ncnc(SCc3cc(=O)c(O)co3)c2c1C +Cc1ccsc1CNC(=O)CN1CCOCC1 +CC(C)COc1nc(N(CCO)C(C)C)ccc1N +CCC(=O)Nc1ccc(NC(=O)N2CCc3cc(F)ccc3C2)cc1 +Cn1nc(C(F)(F)F)c(Cl)c1C(=O)NC(C)(C)C +N#Cc1ccsc1NC(=O)c1ccc(OC(F)(F)F)cc1 +CCOc1ccc(N2CCN(CC(=O)NC(C)C)C2=O)cc1 +CCOC(=O)COC(=O)C=C(C)c1ccccc1Cl +CC(C)C(=O)NC(C)c1ccc(OCc2cccnc2)cc1 +Cc1ccccc1NC(=O)Cn1ccc2c(=O)[nH]ccc21 +Cc1ccc(CC(=O)Nc2cccc(Oc3cnccn3)c2)cn1 +CSc1nccn1-c1cccc(C(=O)OCCN2CCCC2=O)c1 +CN(Cc1nc(C(F)(F)F)cs1)c1nc(N)nc2[nH]cnc12 +CCn1nc(C)c(C(=O)OCC2CCN(CC(F)(F)F)CC2)c1C +CN(CCc1ccc(F)cc1)C(=O)c1cc2c(cc1O)OCO2 +Cc1csc(CNC(=O)Nc2ccccc2C)n1 +O=C(NC1CCOc2ccccc21)c1cccnc1-n1cncn1 +Nc1ccc(NC(=O)c2ccc3c(c2)OCO3)nc1 +CC(C)n1nccc1NC(=O)NCC1(c2ccccc2)CCC1 +CCNC(CCN1CCOCC1)c1ccccc1Cl +Cc1ccc(-n2cnnn2)cc1NC(=O)NCC(C)c1ccccc1 +COC(=O)C(c1cccnc1)N1CCn2c(nn(C)c2=O)C1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2ccc(F)c(Cl)c2)n1 +COCC(O)CN(C)C(=O)CCc1ccc(C)cc1 +COC(=O)NCC(=O)N1CCC(c2nc3ccccc3s2)CC1 +CN(C)S(=O)(=O)c1ccc2[nH]c(CO)nc2c1 +CN(C)C(=O)CNc1ccc(-n2cc(CO)nn2)cc1 +COc1cccc(CNC(=O)N2Cc3cccn3-c3ccccc32)c1 +CN(C)S(=O)(=O)c1cc(Br)ccc1F +CC(=O)N1CCN(c2nc(CC(C)C)c3c(c2C#N)CCC3)CC1 +CCOC(=O)c1cccc(NC(=O)N2CCCC(OCC)C2)c1 +Cc1cc(C)n(-c2ccc(CNC(=O)Cn3cnnn3)cn2)n1 +O=C(c1ccccc1NCc1ccco1)N1CCN(C2CC2)C(=O)C1 +CN(CCC(F)(F)F)C(=O)C1CC(=O)Nc2cc(F)ccc21 +Cc1ccc(S(=O)(=O)CS(=O)(=O)c2ccccc2)cc1 +Cc1cc(NC(=O)c2ccc(F)cc2)n(Cc2ccccc2)n1 +Cc1cc(C(=O)NCC(=O)NCC(O)c2ccccc2)nn1C +O=C(NCCO)Nc1cccc(N2CCOCC2)c1 +C=C(C)CN(CC)S(=O)(=O)c1ccc(F)c(NC(C)=O)c1 +CC(Cc1cccs1)N(C)C(=O)CCSc1ccccn1 +COc1ccc(OCCC(=O)Nc2nnc(C(C)(C)C)s2)cc1 +Cc1cc(N2CCN(C(=O)c3cnccn3)CC2)nc(C(C)C)n1 +Cc1ccc(C(=O)N2c3ccccc3C(C(N)=O)CC2C)s1 +Cc1ccoc1C(=O)Nc1ccccc1Br +CCCc1ncncc1C(=O)N(C)Cc1cc(-c2ccccc2)no1 +Cc1nc2sc(-c3ccc(F)cc3)nn2c1CO +CCc1cccc(OCc2nnc3c(N)cc(Cl)cn23)c1 +CC(=O)NCC1NCCc2c(Br)cccc21 +Cc1nc2ccc(NC(=O)c3cccc(F)c3)cc2[nH]1 +COc1ccccc1C1CC(=O)Nc2[nH]nc(C)c21 +O=C(CNC(=O)c1ccc(-n2cncn2)nc1)OCc1ccccc1 +COC(=O)Nc1cccc(NCc2nc(C3CC3)no2)c1 +NC(=O)C1CN(C(=O)NCCc2cnn(-c3ccccc3)c2)CCO1 +CCNC(=O)c1ccc(NC(=O)c2cc(NC(C)=O)ccc2F)cc1 +O=C(Cn1ccnc1)NC1CCCc2ccccc21 +CN(Cc1ccccc1F)C(=O)CSc1ccccn1 +COc1ccc(C(=O)OCc2ccoc2C)cc1OC(F)F +CC(C)n1nc(C(=O)OCC(F)(F)F)c2ccccc2c1=O +COC(=O)c1sccc1NC(=O)c1ccno1 +CC(C)n1cnnc1SCC(=O)NCc1ccc2ccccc2c1 +NC(=O)C(NC(=O)CC1CCCC1)c1cccc(Br)c1 +Cc1cccc(C)c1NC(=O)N1CCN(C(=O)C(C)(C)C)CC1 +CC(C)(C#N)C(=O)N1CCN(Cc2cccnc2)CC1 +CCC(c1ccncc1)N(CC)C(=O)C1COc2ccc(F)cc2C1 +Cc1occc1CNC(=O)N1CCC(OCC2CCCCO2)CC1 +COc1cccc2cc(C(=O)NCC(=O)NC3CC3)oc12 +COc1cccc(NC(=O)c2nc(C)n(-c3ccc(F)cc3)n2)c1 +O=C(NCCCc1ccc(Cl)cc1Cl)c1n[nH]c(=O)[nH]1 +CCC(CC)NC(=O)C1CC(=O)N(c2cccc(C)c2)C1 +O=C(Nc1cc(Cl)ccc1-n1cccn1)c1csnn1 +CCOC(=O)CC(NC)C(=O)c1ccc(Cl)cc1Cl +CN(Cc1ccccc1)C(=O)CNC(=O)c1cc2sccc2n1C +COc1ccc(C)cc1NC(=O)c1cc2c(nc1N)CCC2 +CCN(CC(O)c1ccc(C)cc1)S(=O)(=O)c1c[nH]cn1 +Cc1ccc(C(=O)N(CCC#N)C2CCOCC2)cc1Cl +CCCn1nnnc1Cn1nc(C2CC2)cc(C(F)(F)F)c1=O +O=C(C1CC1)N1CCCC(c2ccnc(-c3ccc(F)cc3)n2)C1 +CC(C)(C)c1ncc(NC(=O)C2(c3ccccc3)CC2)cn1 +c1cc(CN2CCOC3CN(Cc4csnn4)CC32)ccn1 +COC(=O)c1cc(COC(=O)c2n[nH]c3ccccc23)oc1C +CC(=O)c1ccc(NC(=O)c2noc3c2CCc2ccccc2-3)cc1 +COc1ccccc1CCNC(=O)c1c(F)cccc1F +CCc1ccc(N2C(=O)CC(c3ccc(O)cc3)C3=C2COC3=O)cc1 +COc1cc(C)nc(N2CCN(C(=O)CCn3cc(C)cn3)CC2)n1 +CNC(=O)c1ccc(NC(=O)N(C)C(C)c2ccccc2F)cc1 +Cc1ccc(S(=O)C2CCN(C(=O)OC(C)(C)C)CC2)nc1 +O=C(Nc1cccc(CN2CCCCC2=O)c1)C1CC2CCC1C2 +CCCOCC(=O)N(C)c1nc2ccccc2n1C +CCCCSc1nc2n(n1)C(c1cccs1)C(C(N)=O)=C(C)N2 +CCCn1ncc(-c2ccc(OCC)cc2)c(CO)c1=O +CC(C)(C)OC(=O)N1CCCC(NC(=O)N2CCOCC2)C1 +Cc1nc(CC(=O)Nc2ccccc2C(=O)NC2CC2)cs1 +COc1ccc(C#CCNC(=O)C(C)Oc2ccccc2)cc1 +CCOC(=O)CSc1nc2c(c(=O)n(C)c(=O)n2C)n1CC +CC(C)NC(=O)CCc1cccc(Br)c1 +Cc1cc(C(=O)OCCn2c(C)csc2=O)c2ccccc2n1 +CN1CCN(C(=O)CCNC(=O)OC(C)(C)C)CC1 +COc1ccc(CCn2cnc3ncccc3c2=O)cc1 +Cc1ccc(C(=O)N(C)CC(=O)Nc2cccc(C)c2C)o1 +CN(C(=O)CCc1ccccn1)C1CCN(C(=O)OC(C)(C)C)CC1 +CCOc1cc(C)c(CC(=O)NCCO)cc1C +CCC(=O)Nc1cccc(-c2nc(-c3cnccn3)no2)c1 +CCCc1nc(CNc2ccc(F)c(F)c2)no1 +CCC(=O)N1CCCC1C1CCCN1c1cc(C)nc2ncnn12 +O=C(Nc1ccn(-c2ccncc2)n1)c1cccnc1N1CCCCC1 +COc1cc2c(c(OC)c1O)C(C1CC(=O)C1)NCC2 +Cc1nc(CN(C)CC(c2cccs2)N2CCOCC2)oc1C +CC(=O)N1CCCc2cc(-c3cc(CO)on3)ccc21 +CN(C)c1cccc(C(=O)NCCC(=O)N2CCCCCC2)c1 +Cc1nnnn1-c1cccc(NC(=O)c2c(F)cccc2Cl)c1 +Cc1ncc(CNc2ccc(CC(=O)N(C)C)cc2)s1 +Nc1ccc(NC(=O)c2cc3ccccc3o2)c(Br)c1 +Cc1ccc(C)c(N(CC(=O)N2CCCCC2)S(C)(=O)=O)c1 +COc1ccc(NC(=O)Cc2c(F)cccc2F)c(OC)c1 +O=C(Nc1cnc2n1CCCC2)c1ccccc1N1CCOCC1 +O=C(CSc1cc(-c2ccccc2)ncn1)NCc1cccs1 +CSc1nnnn1-c1cccc(NC(=O)c2cc(C)ccc2C)c1 +Cc1cc(C(=O)CSc2nncn2C)c(C)c(C)c1C +Cc1nn(C)c2nc(C3CC3)cc(C(=O)NC3CCCCCC3)c12 +O=C(c1ccc2c(c1)CCC2)N1CCC(c2nnc3ccccn23)CC1 +Cc1oncc1C(=O)N1CCC2(CC(Oc3cccnc3)CO2)C1 +Cc1nc(CNS(=O)(=O)c2c(Cl)cccc2Cl)cs1 +COCCn1c(C(=O)NCc2cccn2C)cc2cc(Cl)ccc21 +CC(CNc1ncnc2[nH]cnc12)CN1CCCC1=O +Cc1noc(-c2cccc(OCC(=O)NCCc3ccccc3)c2)n1 +Cc1ccc(C(=O)N(CCC#N)C(C)C)cc1Cl +CS(=O)(=O)c1ccccc1NC(=O)NCCC1CCCCC1 +CNC(=O)C1CCCN(C(=O)c2c[nH]c3cc(F)ccc23)C1 +CC(C)(C)OC(=O)N1CC(O)CC1C(=O)Nc1ccccc1F +CCc1ccc(CN2CC(c3nc(-c4cccnc4)no3)C2)cc1 +O=C(CNC(=O)c1ccc(-c2cscn2)cc1)OCC1CC1 +CCc1cc(C(N)=O)c(NC(=O)c2cccc(F)c2F)s1 +Cc1cc(C)nc(SCC(=O)NCc2ccccc2)n1 +CC(C)CNC(=O)c1ccc(NC(=O)c2ccsc2)cc1Cl +O=C(NC1CCc2c(O)cccc21)c1ccncc1 +Cc1n[nH]c(C)c1NC(=O)CN(C)C1=NS(=O)(=O)c2ccccc21 +Cc1nc(Cn2cccc2C(=O)Nc2ccc(C)c(F)c2)no1 +COc1ccccc1NCC(=O)NCc1ccc(F)cc1 +N#Cc1ccc(OCC(=O)Nc2cccc(N3CCCC3=O)c2)cc1 +CCCSc1nnc(C(C)NC(=O)OC(C)(C)C)o1 +Cc1cc(NC(=O)N2CC(C)CCC2C)c[nH]c1=O +CCOc1ccccc1NC(=O)CC(C#N)c1cccs1 +CN1CC(Nc2ccc(Br)cc2C#N)CCC1=O +Cc1ccc(S(=O)(=O)NCc2cccnc2)c(Cl)c1 +Cc1noc(C(C)Sc2nnnn2-c2ccccc2)n1 +COc1cc(-c2cccc(-c3ccn(C)n3)c2)ncn1 +COc1cc(C2NCCc3ccc(Cl)c(F)c32)ccn1 +O=C(NCCc1ccncc1)C1COCC(=O)N1Cc1ccccc1 +Cc1cc(C)cc(NS(=O)(=O)c2cccc(S(N)(=O)=O)c2)c1 +CC(C)n1nccc1NC(=O)NCC1(c2ccc(F)cc2F)CC1 +CCOc1c(Cl)cc(C(=O)N(C)Cc2ccncc2)cc1OC +CC1CN(CCC(O)c2cc(F)ccc2F)CC(C)O1 +COc1ccc(C(=O)N2CCN(Cc3cccc(F)c3)CC2)cc1 +Cc1ccc(F)cc1NC(=O)c1csc(S(N)(=O)=O)c1 +O=C(Nc1nc2ccccc2[nH]1)c1ccc2c(c1)OCCCO2 +O=S(=O)(N1CC=C(c2c[nH]c3ccccc23)CC1)N1CCCCC1 +CCS(=O)(=O)N1CCn2c(Cn3cncn3)cnc2C1C +O=C(NCc1ccc(Cl)cc1)Nc1cn[nH]c1 +COCCN1C(=O)CCC2C1CCN2C(=O)CCc1ccccc1 +CCCC(=O)Nc1nc2cc3c(cc2s1)OCCO3 +CC(=O)N(CCc1ccccc1)CC(=O)NCC1CC=CCC1 +CCNC(=O)Cn1c(CO)cnc1SCc1ccccc1 +CCc1ccc(C(=O)CC2(O)C(=O)Nc3ccc(OC)cc32)cc1 +O=C(COC1CCCC1)Nc1ccccc1NC(=O)c1ccccc1 +Cc1nc(CNC(=O)c2ccc(NC(=O)CC(C)C)c(F)c2)n[nH]1 +CN1CC(NC(=O)c2sccc2Br)CCC1=O +Cc1ccc(NC(=O)COC2CCCC2)cc1S(=O)(=O)N(C)C +Cc1ccc(CNC(=O)C(C)n2nc(C)ccc2=O)cc1 +CC(=O)N(Cc1ccccn1)c1nc2ccccc2s1 +Cc1ccnc(-c2ccc(NC(=O)NCCc3cccc(O)c3)cc2)n1 +Cc1cc(C(=O)Nc2cccnc2-n2ccnc2C)c(C)o1 +COc1ccc(C(=O)N2CCCC(n3cncn3)C2)nn1 +Oc1ccc(Cn2ccnc2CC(F)(F)F)cc1 +O=C(c1cnc(C2CC2)[nH]c1=O)N(CCC1=CCCCC1)CC1CC1 +COC(=O)CC1CN(Cc2cn(C)nc2-c2ccncc2)CCO1 +Cc1cc(NC(=O)C(C)Oc2ccc3c(c2)OCO3)no1 +CC1CCN(C(=O)Cc2csc(NC(=O)c3ccccc3)n2)CC1 +CC(C)(C)NC(=O)c1cccc(NCC(=O)Nc2ccccc2)c1 +O=C1Nc2ccc(Cl)cc2C1Nc1ccccc1 +O=C(NCc1cccc(Cn2ccnc2)c1)c1ccc2[nH]nnc2c1 +Cc1nnc(CN(C)Cc2ccc(-n3cccn3)cc2)n1C +O=C(NCc1ccccc1CO)c1cccc2c1OCCO2 +O=C(c1ccncc1F)N(Cc1cccnc1)CC1CCCO1 +Cc1cc(N(C)Cc2cc(-c3cccs3)n[nH]2)n2nccc2n1 +Cc1nn(CC(=O)N2CCCCC2)c(C)c1CCO +Cc1ccc(C(=O)CC2(O)C(=O)Nc3c(C)cc(Cl)cc32)cc1 +COc1ccc(NC(=O)c2ccn(C3CCCC3)n2)cc1 +COc1ccccc1C(=O)N1CCC(Oc2ccc(C)nn2)CC1 +COC(=O)CNC(=O)c1[nH]c(C)c(C(=O)OC)c1C +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1ccncc1 +CCN(CC(=O)NC(C)C)C(=O)c1c(C)nc(C(C)(C)C)[nH]c1=O +O=C(CSc1ccc(F)cc1F)Nc1ccc2c(c1)OCO2 +Cc1nnc(NCc2cc(F)ccc2Br)c(C#N)c1C +Cc1nc(-c2noc3ccc(C(=O)NCc4cccs4)cc23)co1 +CCCCOC(=O)CN1CCN(C(=O)N(C)C)CC1 +CC(C)Oc1ccc(C(O)CCN2CCOCC2)cc1 +CCN(CC)S(=O)(=O)c1cc(C(=O)N(C)C)ccc1Cl +O=C(Cn1ccccc1=O)N1CCN(Cc2ccsc2)CC1 +Cc1cccc2cc(-c3noc(-c4cccs4)n3)c(=O)[nH]c12 +O=C(c1cccs1)N1CCc2ncnc(NC3CCC3)c2CC1 +CC(C)N(C(=O)C1(c2ccccc2)CCOCC1)C(C)C +COc1ncccc1CNC(=O)c1ccc2c(c1)CCN2C(C)=O +O=S(=O)(CC1CCOC1)N1CCC(Oc2cccnc2)C1 +CN(C(=O)CCC(C)(C)C)c1cc(F)ccc1F +Cn1c(C(F)(F)F)nn(CCNC(=O)NCc2cccs2)c1=O +CN(C)S(=O)(=O)c1cccc(C(=O)Nn2cnc3ccccc32)c1 +Cn1cc(CCCNC(=O)c2scnc2C2CC2)cn1 +CC(C)(C)C(NC(=O)Nc1nnc(C(F)F)s1)C(N)=O +CCCN(CC(=O)OC)C(=O)c1ccc(C)n1C +Cn1c(=O)[nH]c2c(ncn2CC(=O)c2ccc(Cl)cc2)c1=O +CC(=O)NCC(=O)N1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +COC(=O)C1CC1C(=O)N(CCC#N)c1ccccc1 +O=C1COc2cc(C(=O)OCC(F)(F)F)ccc2N1 +O=C(NCC(O)c1ccc(F)cc1)c1cccs1 +NC(=O)CN1CCOC(c2ccccc2C(F)(F)F)C1 +CC(C)NC(=O)CNC(=O)COc1ccc(Cl)cc1 +O=C(c1ccc(OC(F)(F)F)cc1)N1CCCCC1C1OCCO1 +CC(Nc1ccc(N)cc1C(F)(F)F)C1CCCO1 +FC(F)(F)c1nnc2n1CCN(Cc1ccccc1-n1cccn1)C2 +Cc1cc(CNS(=O)(=O)c2ccc(F)cc2F)c(C)o1 +N#Cc1cccc(Nc2nnc(SCCO)s2)c1 +COc1cccc(C(=O)N(CC(C)O)C(C)(C)CO)c1 +COc1cccc2c1cc(C(=O)Nc1ccccc1)n2C +CCOc1ccccc1NC(=O)NCc1cccnc1OCC +CCCC1CN(C(=O)C2CCC(C(N)=O)CC2)CCO1 +COCCN(C)C(=O)Nc1ccccc1-n1cccn1 +N#Cc1c[nH]nc1Cc1cccc(Br)c1 +Cn1ccc2ccn(Cc3nc(C4CC4)no3)c(=O)c21 +COc1cccc(-c2ccnc3c2c(=O)n(C)c(=O)n3C)c1 +O=C1CCCc2[nH]c(=O)c(C(=O)Nc3cccnc3-n3cccn3)cc21 +O=C(Nc1nc(-c2cccnc2)cs1)c1coc2ccccc2c1=O +CCc1noc(CC)c1CNC(=O)Cn1ccc(=O)n(C)c1=O +CCCNc1ncnc(Nc2cccc3cccnc23)c1N +CCOc1ccc(NC(=O)c2cnc(C)c(N)c2C)cc1 +Cc1ccc(NC(=O)C2CCCN(S(C)(=O)=O)C2)cc1F +CCc1onc(C)c1C1CCCN1C(=O)c1ccccc1OC +O=C(NCCNC(=O)N1CCN(Cc2cccnc2)CC1)C1CC1 +Cc1ccc(N)cc1NC(=O)C(C)Sc1ncccn1 +CN(CC(=O)N1CCN(c2nccs2)CC1)S(C)(=O)=O +Cc1nc(-c2nc[nH]n2)sc1C(=O)NC1c2ccccc2CC1O +Cc1nc(N)nc(-c2ccc3c(c2)NC(=O)CS3)n1 +Cc1ccc(C(=O)COc2nc(C)nc3ccccc23)cc1 +CCC(C)Oc1cccc(-c2cnn(CC)c(=O)c2N)c1 +N#CCCNC(=O)CSc1n[nH]c(=O)n1C1CC1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCN(C2CCCCC2)CC1 +Cc1nc(Cn2nnc(-c3cccc(F)c3)n2)oc1C +COc1cc(OC)c(OC)cc1CNC(=O)c1ccccc1O +CCOc1c(CN2CCOC(C(N)=O)C2)c(C)nn1CC(C)C +Cc1noc(CNc2cc(S(C)(=O)=O)ccc2C)n1 +O=C(CCC(=O)N1CCN(C(=O)C2CCCO2)CC1)c1ccccc1 +Cc1nc(CN(C)C(=O)c2csnn2)cs1 +Nc1c(-c2cccs2)nc2scc(-c3ccncc3)n12 +O=C(c1ccc2[nH]c(-c3ccncc3)nc2c1)C1CC1 +COc1ccc(NC(=O)NCC(=O)N2CCCC2)c2cccnc12 +CC(O)C(=O)N1CCN(c2ccc(C(F)(F)F)c(C#N)c2)CC1 +NC(=O)C1(CNC(=O)COc2ccc(F)cc2F)CCOCC1 +O=C(Nc1ccsc1-c1nnc(C2CC2)o1)c1ccoc1 +Cc1cc(C)n(CCC2CC(=O)Nc3cc(O)c(C)cc32)n1 +CCS(=O)(=O)NCCNS(=O)(=O)c1ccc(C)cc1 +CCNC(=O)N1CCN(C(=O)c2ccc(-c3cnco3)cc2)CC1 +c1cncc(-c2n[nH]cc2CNc2ccc3nc(C4CC4)oc3c2)c1 +CCc1ccc(NC(=O)N2CCCC2c2c(C)n[nH]c2C)cc1 +CC(C)c1ccc(C2NC(N)=Nc3nc(=O)c4ccccc4n32)cc1 +Cc1nc(N(C)C)sc1CN1CCOCC12CCC2 +CC(OC(=O)c1cnccn1)C(=O)N1CCc2ccccc21 +CC1CC=CCC1COC(=O)c1ccn(C)c(=O)c1 +CCCn1c(SC(C)C(=O)NC2CC2)nnc1-c1ccncc1 +CN(CC1(CO)CCOCC1)C(=O)C(c1cccc(F)c1)N(C)C +Cc1nc(NC(=O)CC(O)(c2nccn2C)C(F)(F)F)sc1C +Cc1cc(C)c(NC(=O)C(C)Sc2nnnn2C)c(C)c1 +Cc1[nH]c(C(=O)Nc2cnn(C(C)(C)C)c2)c(C)c1C(=O)OC(C)C +Cc1cc(C)n2nc(SCC(=O)Nc3c(C)nn(C)c3C)nc2n1 +CC(C)Oc1ccccc1CNC(=O)Nc1cn[nH]c1 +CN(CCc1ccccn1)S(=O)(=O)c1cc(F)ccc1F +CCCOc1ccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)cc1 +O=C(NCCOc1cccnc1)c1cccc(CN2CCCC2=O)c1 +CCNc1ccc(COc2ccc(F)c(F)c2)cn1 +O=C(Cn1c(=O)oc2ccccc21)NCc1ccc(Cl)cc1 +COCC(=O)Nc1ccc(Oc2cccc(C(N)=O)c2)cc1 +CC(=O)Nc1cccc(OCCNC(=O)c2ccccc2O)c1 +CNC(=O)C(C)CNC(=O)c1cc(COc2ccccc2)[nH]n1 +Cc1cccc(OC(F)F)c1NC(=O)c1ccc(-n2ccnn2)cc1 +O=C1C2CCCN2C(c2ccccc2Cl)N1c1ccccn1 +COCC(O)CN(C)C(=O)Cc1cc(Cl)ccc1Cl +O=C(CNC(=O)c1cnc(C2CCCO2)s1)OCc1ccccc1 +Cc1ccc(Nc2ccc(S(=O)(=O)N3CCOCC3)cn2)cc1C +CNC(=O)C1Cc2ccccc2CN1C(=O)c1cccc(Cl)c1 +Cc1cc(C)cc(N2CC(C)Cn3c2nc2c3c(=O)[nH]c(=O)n2C)c1 +COCCCNS(=O)(=O)c1cnn(-c2ccccn2)c1 +CCNC(=O)c1cccc(CNC(=O)NCC(=O)NC(C)(C)C)c1 +CC(OC(=O)c1ccc(-c2ccc(F)cc2)o1)C(=O)N(C)C +Cc1cccc(CN(C(=O)CSc2nncs2)C2CC2)c1 +CN(CCOc1ccccc1)C(=O)c1ccccc1 +Cn1c(SCC(=O)N2CCCCCC2)nnc1-c1ccncc1 +Cc1nc(-c2cn(-c3cccc(Cl)c3)nn2)no1 +COC(=O)C(C)(C)N(C)C(=O)C(C)Oc1ccccc1C#N +CCn1c(SCC(=O)c2ccc(F)cc2)nnc1-c1ccco1 +N#Cc1ccccc1NC(=O)CSc1ccccc1N +CCCOc1ccc(CN2CCC3(C2)OCCO3)cc1OC +Cc1cc(NC(=O)c2cc(-c3cccs3)n[nH]2)ccn1 +CCc1c(C)sc(NC(=O)C2CCCC2)c1C#N +COCCC1CCN(C(=O)CCc2ccccc2)CC1 +Cc1cccn2c(=O)cc(CN3CC(C)OC(C)C3)nc12 +CCNc1ncc(C(=O)NCc2ccc3sccc3c2)cn1 +COc1ccc(OC)c(NC(=O)c2ccc3nccnc3c2)c1 +COc1ccccc1C(C)NC(=O)C(C)Nc1ccn(C)n1 +CC(=O)NC(C)C(=O)NCc1ccc(OCc2ccccn2)cc1 +Cc1cc(C(=O)NC(C)CN(C)c2ccccc2)c(C)o1 +O=S(=O)(c1ccc(F)c(F)c1)n1cnc2ccccc21 +Cc1ccsc1CNC(=O)Cn1c(=O)sc2ccccc21 +COc1cccc(C(NC(=O)c2cccc(C#N)c2)c2nccn2C)c1 +Cc1ccc(OCC(N)=O)c(-n2cnc3c(C)ncnc32)c1 +COC1CCCC(OC(=O)c2ccc(-n3ccnn3)cc2)C1 +COC(=O)c1cccc(NC(=O)CSc2ccc(OC)cc2)c1 +CCOC(=O)C1CCCN(C(=O)c2nccc3c(N)cccc23)C1 +Cc1c(NS(C)(=O)=O)cccc1C(=O)NCCC1=CCCCC1 +CC(C)(C)c1noc(CCC(=O)OCC(=O)N2CCCC2)n1 +Cc1nn(C(=O)CCCC(=O)N2CCN(C)CC2)c2ccccc12 +COc1cccc(C(=O)N2CCN(C(=O)CCC3CCCC3)CC2)c1 +COc1ccc(Cl)cc1-n1cc(C)c(C)c(C#N)c1=O +CCN1CCc2nc(NC(=O)CCc3ccccn3)sc2C1 +CC(=O)Nc1cc(C2=CCCN(Cc3cc(=O)[nH]c(C)n3)C2)nn1C +Nc1cccc2c1N(CC(=O)Nc1nccs1)C(=O)CO2 +COc1ccc(C)cc1-c1cc(C#N)nn1CC(N)=O +CC1CCc2sc(C(=O)N3CC(C(N)=O)CCC3C)cc2C1 +Cn1ccc(-c2ccc3c(c2)OCCO3)c(C#N)c1=O +COc1ccc(OC(=O)Cn2c(C)c(C)sc2=O)c(C(C)(C)C)c1 +Cc1cccc(-c2nnc(SCC(=O)NC(C)(C)C)o2)c1 +CCOc1ccc(OCC(=O)N2CCOC(C)(C)C2)cc1 +CN(CCOc1ccc(Cl)cc1)S(=O)(=O)c1cn[nH]c1 +COc1ccccc1CC(=O)Oc1cccc(NC(=O)C2CC2)c1 +CNC(=O)c1ccc(NC(=O)c2cc(F)cc(F)c2)cc1 +CC(C(=O)Nc1cccnc1)n1nc(-c2ccccc2)ccc1=O +O=C(c1ccccn1)N1CC2CCCC2(COCC2CCOCC2)C1 +Cc1ccc2[nH]cc(S(=O)(=O)c3ccc(F)cc3)c(=O)c2c1 +O=C(Nc1ccc(F)cn1)c1c(F)cc(Br)cc1F +CC(Cc1ccsc1)NC(=O)c1nccnc1N +O=C(Cn1c(=O)oc2ccc(Cl)cc21)N1CCCc2ccccc21 +CC(c1ccncc1)N(C)C(=O)c1cc(F)c(F)c(F)c1 +Cc1ccc(C#N)cc1S(=O)(=O)NCCC(F)(F)F +CCOC(=O)c1cnn2ccc(NC(=O)CC(C)C)cc12 +CCc1oc(C(=O)N2CCC3(CCOC3)C2)cc1C +Cc1ccccc1NCC(=O)N(CCC#N)CCC#N +CCc1ccc(-c2ncc(C(=O)N(CC)CC)c(N)n2)cc1 +c1csc(-c2nnc(CN3CCN(c4nccs4)CC3)o2)c1 +CN(CC(=O)Nc1cccc2ncccc12)c1ccccc1 +COc1cccc(CNC(=O)c2ccnc(SC)c2)c1 +CN(Cc1cccc(C#N)c1)C(=O)CCOc1ccccc1Cl +CCCCNC(=O)c1cnc(-c2ccc(Cl)cc2)nc1N +COc1ccc(S(=O)(=O)C2CCN(C(=O)C3CCC3)CC2)cc1 +CC(C)Cn1ccc2cc(NC(=O)NC3CCC(O)CC3)ccc21 +CC1CCCCN1C(=O)c1c(-c2ccccn2)cnnc1N +CNC(=O)COC(=O)c1cnn(-c2ccccc2Cl)c1 +COCCNC(=O)N1CCC(Cc2nc3cccnc3n2C)C1 +Cc1ccsc1CNC(=O)C1Cc2ccccc2C(=O)O1 +O=C(Cc1ccc2c(c1)OCO2)N1CCC(N2CCNC2=O)CC1 +CC(C)N(CCO)C(=O)CN1CCN(c2ccc3c(c2)OCO3)C1=O +O=C(Cn1cc(-c2ccccc2)cn1)Nc1ccccc1OC(F)F +CN(C)C(=O)CNC(=O)CN(C)c1ccc(Cl)cn1 +COCc1ccccc1CNC(=O)c1ccc(F)cc1 +Cc1ccc2nc(C(=O)NCCc3c[nH]c4ccccc34)cn2c1 +CCOc1cccc(C(=O)NCc2cc(OC)c(OC)cc2Cl)c1 +CC(O)CN(C(=O)NCc1cc(F)cc(Br)c1)C(C)C +Cc1ccsc1CN(C)C(=O)c1cc(=O)c2ccccc2o1 +Cc1ccc(S(=O)(=O)NC2(C#N)CCCCC2)s1 +CCOC(=O)C1CCN(C(=O)c2nnsc2C)CC1 +CSc1c(C)cccc1OCC(=O)NCc1ccccc1 +CCCCOC(C)C(=O)Nc1ccc2c(c1)oc(=O)n2C +CCn1c(N)nc2cc(C(=O)NCc3nnc4n3CCCC4)cnc21 +CC(OCC1CC1)C(=O)NCc1ncc(-c2ccccc2)[nH]1 +COc1ccc(NC(=O)c2c(C)nn(C)c2C)cc1F +Cc1ccc2[nH]c(CN(C)C(=O)c3cnc(C)cn3)nc2c1 +O=S(=O)(NCc1nnc2ccccn12)c1ccc(Cl)cc1F +Cc1ccc(S(=O)(=O)CC(C)Nc2ncc(Cl)cn2)cc1 +COc1cc(F)c(S(=O)(=O)NCC(C)C)cc1OC +CCc1cc(C(O)CC(C)C)cc2c1OCCC2NC(C)=O +COc1cc2ccccc2cc1C(=O)Nc1cc(C)nn1C +Cc1csc(C(C#N)C(=O)C(C)Oc2ccc(F)cc2Cl)n1 +CN(CC(=O)NC(C)(C)C)C(=O)c1ccc(F)cc1 +CC(OCC1CCCO1)C(=O)Nc1ccc(Cl)cc1N +CSc1ccc(C(=O)NCc2cccc(C#N)c2)cc1 +O=C(NCc1ccc(F)cc1)c1sccc1Br +Cc1ccc(OCCCC(=O)NCc2ccco2)cc1 +Cc1cc(C(O)C(=O)N(C)CCc2ccncc2)ccc1F +CCCNC(=O)CCc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CC(Oc1cccc(Cl)c1)C(=O)NCC1CCCO1 +CCCC(=O)NCC(=O)Nc1ccc(C)cc1OCC +CC1=CC=CC2=NC(c3nc(C4CC4)n[nH]3)C(F)N12 +COCCCNC1=NS(=O)(=O)c2cc(C)ccc2N1 +C=C=Cn1c(C2CC(=O)N(c3ccc(C)c(C)c3)C2)nc2ccccc21 +Cc1nn(C)cc1NCc1ccn(C2CCCC2)n1 +Cc1cc(CC(=O)N2CCOc3ccccc3C2)no1 +CCC(C)(NC(=O)CNC(=O)c1ccccc1)C(=O)NC1CCCC1 +CCCNC(=O)C1CCN(C(=O)CCOc2cccc(C)c2C)CC1 +CC(O)C1CCCCN1C(=O)CNC(=O)c1cc(F)cc(F)c1 +CC(=O)Nc1ccc(F)c(C(=O)OCC(=O)Nc2ccccc2)c1 +CC(C)Oc1ccccc1C(C)NC(=O)Nc1cnn(CC(N)=O)c1 +COCC(=O)Nc1[nH]ncc1-c1cccc(Cl)c1 +CCCCN(C)C(=O)CCC(O)c1ccc(C)cc1 +Cc1ccc(Cn2c(C(=O)N3CCOCC3)cc3occc32)cc1 +Cc1nn(C)c(C)c1CCC(=O)N1CCN(Cc2cccs2)CC1 +CN(C)C(=O)c1ccc(NC(=O)CCc2ccco2)cc1 +COC(=O)c1cc(S(=O)(=O)Nc2ccc(C)cc2C)cn1C +COc1ccc(OC)c(-n2nnnc2SCc2cnc(C)cn2)c1 +O=C(Cc1ccc(Cl)cc1)Nc1ccc(N2CCCC2)nc1 +COCCn1c(-c2ccco2)nc2cc(Cl)ccc21 +Cc1noc(C)c1CN(C)c1ncnc2c1cnn2C +COc1cccc(OC)c1C(=O)OC(C)C(=O)NC1CCCC1 +Cc1ccc(NC(=O)Cn2cnc(-c3ccccc3)cc2=O)cc1C +CC(C#N)CN(C)CCc1nc2ccc(N)cc2[nH]1 +Cc1nc(COc2cccc3c2CCC3=O)oc1C +Cc1cc(F)ccc1CCNC(=O)c1ccc(-c2ccco2)[nH]c1=O +NC(=O)NCCCCC(=O)NC1CCc2cc(Cl)ccc21 +COC1CCCC(OC(=O)CCNC(=O)c2ccsc2)C1 +O=S(=O)(c1cccs1)n1cnc2ccccc21 +CC(C)c1noc(C2CCCN(C(=O)Cc3cccs3)C2)n1 +Cc1cc2nc(C(=O)Nc3cc(F)cc(F)c3)cc(C)n2n1 +O=C1CCC(C(=O)NCc2cc3ccccc3o2)N1 +N#Cc1ccc(OCCN2CCN(c3ccccc3O)CC2)cc1 +O=C(NCC1CCCC1O)Nc1cccn(Cc2ccccc2)c1=O +CC(=O)N1CCc2cc(CNC(=O)CC3CCCC3)ccc21 +CNC(=O)NC(C)(C)C(=O)NC1CC1c1ccccc1C(F)(F)F +CCc1ccc(CC(=O)Nc2cc(C)nn2C(C)C)cc1 +CCCS(=O)(=O)N(C)c1ccc(F)c(NC)c1 +CCC(CC)C(=O)NCCS(=O)(=O)N1CCc2ccccc2C1 +CC(C)(C)OC(=O)N1CCCC(CNc2ncccc2O)C1 +N#Cc1ccc(OC(F)F)c(NC(=O)C2CCCO2)c1 +O=C(CCn1ncc(=O)c2ccccc21)Nc1cccc(F)c1F +CNc1nnc(-c2ccc(-c3cccs3)n(C)c2=O)s1 +COc1ccc(CCC(=O)Nc2cc(-c3ccncc3)n[nH]2)cc1 +Cc1cc(C(=O)N2CCCC(C)C2)ccc1NCc1ccccc1C#N +Cc1ccc2ncn(C3CCN(C(=O)CC(C)C)CC3)c2c1 +O=C(Oc1cccc(F)c1)C1CCCN1C(=O)c1cccs1 +COC(=O)CC(C)N1CCC(N2CCOCC2)C1 +CC(C)Cc1nnc(NC(=O)C2CCCN(C(N)=O)C2)s1 +CCCCCC(=O)Nc1ccc(CN2CCCC2=O)cc1 +CCC1c2cccn2CCN1C(=O)c1cc2ncc(CCO)cn2n1 +COc1ccc(C2Nc3ccccc3C(=O)N2C)c(OC)c1 +CN(C(=O)c1cc(F)cc2[nH]cnc12)C1CCCCC1 +CCCCNC(=O)c1csc(NC(=O)c2cccc(F)c2)n1 +O=C(c1cnns1)N1CCCC1Cc1cccc(F)c1 +CCc1ccc(CC)c(NC(=O)N(C)CCC#N)c1 +O=C(C1CC1)N1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 +C#CCN(CC#C)C(=O)c1ccc(OC(C)(C)C)nc1 +CN(C)C(=O)c1ccc(CN2Cc3ccccc3-c3ccccc3C2)[nH]1 +CNC(=O)c1cccc(CCC(=O)NC2(C)Cc3ccccc3C2)c1 +O=C(OCC(=O)N1CCCc2ccccc21)c1cccs1 +NC(=O)c1csc(NC(=O)C2CC(=O)N(CC(F)(F)F)C2)n1 +O=C(NCCOc1cccc2ccccc12)C(O)c1ccccc1 +CC(=O)N1CCC(NC(=O)CNc2c(C)cccc2C(C)C)CC1 +Cc1nc(COc2ccc(CNc3ccc(F)c(C)c3)cc2)no1 +COc1cccc(CNC(=O)c2n[nH]c3c2CCc2ncccc2-3)c1 +O=C(c1cc(F)cc(F)c1)N1CCN(c2cccc(Cl)c2)CC1 +COCCc1[nH]nc(N)c1-c1c(C)cc(C)cc1C +CC(NC(=O)N(Cc1ccccc1F)C1CC1)c1ccncc1 +CC(C)CCNC(=O)Cn1c(=O)c2cccn2c2cccnc21 +O=C(c1cccc2c1OCCO2)N1CCCC(n2cccn2)C1 +COCC(NC(=O)c1ccc(F)c(Cl)c1)C(N)=O +O=c1c2ccccc2nc(SCCn2cccn2)n1C1CC1 +O=C(c1cccs1)c1conc1C(=O)c1ccco1 +CSc1ccc(C(=O)N(C2CC2)C(C)C(C)C)cc1 +CC(=O)N1CCN(C(=O)CSc2ccccn2)CC1 +COc1ccc2[nH]cc(NC(=O)NCCN3CCOCC3)c(=O)c2c1 +CS(=O)(=O)NCC12COCC1CN(C(=O)N1CCCC1)C2 +O=C(Nc1cccc(C(F)(F)F)c1)c1ccc(C(F)(F)F)nc1 +CC(C)C(C(=O)Nc1nncs1)n1nnc(-c2ccccc2)n1 +Cc1cccc(NCc2c(CO)cnc(C)c2O)c1C +CC(=O)NCc1ccc(C(=O)Nc2ccc(C)cc2)cc1 +Cc1nc(CNc2nc(-c3cccnc3)nc3c2c(C)nn3C)n[nH]1 +Cc1cc(C)c(CNC(=O)c2csc(-c3ncccn3)n2)c(C)c1 +Cc1csc(CN2CC3OCC(C(=O)Nc4cccnc4)C3C2)n1 +CCNC(=O)c1ccc(C)c(NC(=O)Cc2ccc(F)cc2F)c1 +CC(=O)NCc1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1 +O=C(NCc1cccc(CN2CCOCC2)c1)Nc1cccc(F)c1 +O=C(NCCn1c(=O)oc2ccccc21)c1ccco1 +CSc1ncccc1C(=O)Nc1ccc(Cl)cn1 +CCOCCCn1cnc2sc(C)cc2c1=O +Cc1ccc(S(=O)(=O)NCC#Cc2ccccc2F)s1 +Cc1ccc(C)c(NC(=O)c2ccc3[nH]cnc3c2)c1 +CC(C)OCc1cccc(NC(=O)NCc2cccc3cccnc23)c1 +CCc1nnc(CNC(=O)c2cccc(-n3cnnc3)c2)s1 +Cc1c(-c2ccnc(N)n2)cnn1-c1ccccc1 +Cc1ccccc1NC(=O)n1ncc2ccccc21 +CCOC(=O)c1nn(-c2nc3ccccc3s2)c2c1CNCC2 +N#CCSc1nnc(N)n1CC(=O)Nc1ccccc1 +COCCOc1ccccc1NCC(=O)N1CCCCC1C +CCC(C#N)CCC(=O)Nc1cccc(Br)c1 +CCCOc1cccc(-c2cc(C#N)c(=O)n(C)n2)c1 +COc1ccc(SCC(=O)N2CCOc3ccc(F)cc32)cc1 +Cc1cccc2nc(C(=O)OCC3CC3(Cl)Cl)cn12 +CC(C)n1nccc1C(=O)Nc1nc2c(F)cccc2s1 +O=C(CC1CCCO1)NCCCOc1cccc2cccnc12 +Cc1ccc(C(=O)Nc2nccs2)cc1NC(=O)c1ccco1 +CCOc1ccc(C(=O)N(C)C)cc1NCc1ncc(C(C)(C)C)o1 +Cc1cccc2c(=O)n(CC(=O)N3CCCCC3C)cnc12 +O=C(Nc1ccccc1-n1cccn1)N(Cc1ccncc1)C1CC1 +COCCNc1ncc(Br)c2c(F)cc(F)cc12 +CCCCC(=O)N1CCC2(C1)C(=O)Nc1ccccc12 +Cc1ccc2c(C)c(C(=O)NCCn3nc(C)nc3C)oc2c1 +Cc1ccsc1C1CC(=O)Nc2cc(N3CCN(C)C3=O)ccc21 +CN(CC1COCCO1)c1nccc(N2CCC(O)CC2)n1 +CC(C)OCCCNS(=O)(=O)c1ccc(N)cc1 +Cn1c(C(=O)NC(C)(C)C)nnc1-c1ccc(F)cc1 +OCc1c(-c2ccncc2)nc2c(Br)cccn12 +Cc1cc(C)n(C(=O)CNc2ccccc2Cl)n1 +CCCCn1nc(C)c2c(C(=O)Nc3ccccn3)cc(C3CC3)nc21 +Cc1cc(F)c2c(c1)C1(NC(=O)c3ccccc3N1C)C(=O)N2 +COc1ccccc1-n1cnnc1S(=O)CC1CCCCO1 +CC(C)CC(=O)Nc1ccc2c(c1)CCN2C(=O)c1cccnc1 +Cc1cccc(=O)n1CCC(=O)NCc1ccc(S(N)(=O)=O)cc1 +CC(C)C(=O)NCCn1nc(C(F)(F)F)cc1C1CC1 +N#Cc1cccc(-c2csc(-c3nc[nH]n3)n2)c1 +CNc1nc(NCc2cccc(Cl)c2)c2cnn(C)c2n1 +CC(C)NC(=O)c1coc(COc2cccc3cnccc23)n1 +CNC(=O)Cc1ccc(NC(=O)Cc2ccc(OC)cc2)cc1 +Cn1c(COC(=O)C2COc3ccc(F)cc3C2)nnc1C1CC1 +CC(C)CCn1ccc(NC(=O)N2CCc3cc(F)ccc3C2)n1 +CCCc1ccc(C(=O)CCN2CCN(C(C)=O)CC2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)c1cc2c([nH]c1=O)CCCC2 +COc1cccc(C(N)=O)c1OCC(=O)N(C(C)C)C(C)C +Cc1nn(C)cc1CNC(=O)c1cc(Cl)ccc1Cl +NC(=O)c1cccc(NC(=O)c2ccc(-n3ccnn3)cc2)n1 +Cc1cccc(C)c1OCCCC(C#N)C(=O)N1CCCC1 +CCN(CCC#N)C(=O)COc1ccccc1Br +COc1ccc(NC(=O)C2C=CCN2C(=O)c2ccco2)cc1 +CC1CCCN(c2ccc(-c3ccc(=O)n(C)n3)cc2N)C1 +CN(CCC(O)c1ccccc1)C(=O)c1cccc(-n2cnnc2)c1 +COCCS(=O)(=O)N1CCc2cc(N)ccc21 +CCCCNC(=O)Nc1ccc2c(c1)C(C)(C)C(=O)N2CC(=O)OC +CCOC(=O)c1c(C)[nH]c(C(=O)N2CCN(CCO)CC2)c1C +O=C(Nc1cccc2[nH]ncc12)NC1CCCCC1 +Cc1nc(-c2cnc(C(C)C)[nH]c2=O)n(C2Cc3ccccc3C2)n1 +COc1ncccc1CNC(=O)NCC1(c2ccccc2F)CC1 +CN(Cc1ccccc1Br)C(=O)Cn1ccc(N)n1 +Cn1cccc1-c1cc(C(=O)NCCc2c[nH]c3ccccc23)[nH]n1 +Cc1ccc(NC(=O)Cn2nc(C)c(N)c2C)cc1 +O=C(Nc1ccccc1)c1ccc(NC(=O)C2CCOCC2)cc1 +COc1ccc(NC(=O)CN2CC(C)c3ccccc32)cc1OC +Cc1ccc(C(=O)Nc2ccc(F)c(F)c2F)c(N)n1 +COC(=O)c1ccccc1OCC(=O)NCC(F)(F)F +Cc1nn(CC(=O)Oc2ccc3c(c2)OCO3)c(C)c1Cl +CCC(C)NC(=O)CN1C(=O)CNc2cc(OC)ccc21 +Cc1nc(-c2ccc(NC(=O)NCc3ccncc3)cc2)cs1 +NC(=O)c1ccc(S(=O)(=O)N(Cc2ccc(F)cc2)C2CC2)cc1 +O=C(NCc1nnnn1-c1ccc(F)cc1)c1ccc(F)c(F)c1 +O=C(NCCCn1cccn1)Nc1ccc(Oc2ccccc2)cn1 +CC1(C)C(NC(=O)COc2ccc(F)cc2)C2CCOC21 +C=CCNC(=O)NCC1(c2ccc(OC)cc2)CCOCC1 +Cc1cc(S(=O)(=O)n2ccnc2)ccc1Cl +Cn1cccc(C(=O)NCC2(c3ccc(F)cc3)CC2)c1=O +Cc1ccc(-c2ncco2)cc1NC(=O)NCCN1CCOCC1 +Cc1oc(-c2ccccc2)nc1CC(=O)N1CCC(CC(N)=O)CC1 +O=C1NCC(C(=O)N2CC=C(c3c[nH]c4cc(F)ccc34)CC2)N1 +CN(C)c1ccc(NC(=O)CNC(=O)c2ccoc2)cn1 +CCn1c(N2CCN(C(C)=O)CC2)nc2c(C)nn(C)c2c1=O +CCC(=O)c1ccc(OCC(=O)NC2CCCC2)cc1 +O=C(NC1CC1)C1CCN(c2ncnc3c2oc2ccccc23)CC1 +CCCOc1cc(C)ccc1NC(=O)c1csnn1 +Cc1cc(C(=O)Nc2cccc(-c3nc4ccccc4o3)c2)no1 +COc1ccc(S(=O)(=O)N(Cc2ccccc2)C(C)C)cc1 +CN(C)S(=O)(=O)c1ccc2c(c1)CCN2C(=O)c1ccc(F)cc1 +Cc1nc2cc(NCc3cc4ccccc4[nH]c3=O)ccc2o1 +Cc1ncc(CNC(=O)CCn2cnc3ccccc3c2=O)s1 +Cc1ccc(CCC(=O)N2CCC(NC(=O)c3ccoc3)CC2)o1 +CCOc1ccccc1CCNC(=O)N1CCOCC1C1CC1 +O=C(Nc1ccc2c(c1)CCO2)c1cccnc1N1CCCC1 +O=C(Nc1ccccc1F)N1CCC2(CCC(=O)N(C3CC3)C2)CC1 +CCN(CC)C(=O)CNc1cc(CO)ccc1Cl +CC(C)(C)CC(=O)N1CCN(CCNC(=O)c2cccs2)CC1 +Cc1nc(NC(=O)NC2CCc3ccccc3C2)nn1C +COC(=O)C1CCN(C(=O)C(C)Sc2ccc(C)cn2)CC1 +CC1CN(CCC(O)c2cccc(Cl)c2)CCO1 +O=C(NCc1csc2c1CCCC2)C1CCCCn2nnnc21 +COc1ccccc1CN(CCO)C(=O)Nc1ccc(C)cc1OC +COc1ccc(F)cc1NC(=O)N1CCOC(c2cccs2)C1 +Cc1nc2c(c(=O)[nH]1)CCN(C(=O)c1nc(-c3ccccc3)[nH]c1C)C2 +COc1ccc(NC(=O)Cn2c(C)nc3ccc(F)cc3c2=O)cn1 +Cc1nc(CSc2nnnn2-c2cccc(C)c2C)cs1 +CCNc1cc(C)nc(Nc2ccc(NC(=O)c3ccco3)cc2)n1 +CCCCCS(=O)(=O)NCC1CC(=O)Nc2ccccc21 +Cc1ccc(C(=O)Nc2cc(N)ccc2C)c(C)c1 +Fc1cnccc1C1NCCc2c1ccc1cc[nH]c21 +Cc1cc(-c2nc(-c3ccc(C#N)cn3)no2)n(C)n1 +CC1CCCC(NC(=O)c2cccc3c2OCCO3)C1 +COc1ccc(Cl)cc1C(=O)N1CCN(c2nccs2)CC1 +Cc1cc(NC(=O)c2nn3cccnc3c2Cl)no1 +COc1ccc(CCNC(=O)Cc2c(C)noc2C)c(OC)c1 +O=C(NCc1ccccc1F)c1cn2cc(Cl)ccc2n1 +Cc1ccnc(NC(=O)C2CCN(C(=O)Nc3ccccc3)CC2)c1 +CN(C)c1ccccc1NC(=O)c1ccc(-n2cncn2)nc1 +COc1ncnc2c1CCN(C(=O)c1ccccc1F)C2 +COCc1ccccc1C(=O)N1CCN(C(C#N)c2ccccc2)CC1 +CC(Oc1ccc(Br)cc1)C(=O)NCCCO +NS(=O)(=O)c1ccc(CNC(=O)c2cnn3c2OCCC3)cc1 +CCOC(=O)c1cccc(NC(=O)C2CCN(C(=O)N(C)C)CC2)c1 +Cc1ccccc1OC1CCN(C(=O)CN2CCCCC2=O)CC1 +CCOc1ccccc1-c1c(C#N)c(N)nc2c1CCC2 +Cc1nnc2n1CC(NC(=O)c1cc3c(s1)CCC(C)C3)CC2 +O=c1[nH]c(=Cc2ccc(F)cc2)c(=O)[nH]c1=Cc1ccc(F)cc1 +Cc1cc(Cl)ccc1NC(=O)C1CC(=O)N(Cc2ccccc2)C1 +NC(=O)c1cc(S(=O)(=O)Nc2cccc(O)c2)cs1 +CC1CCCN(C(=O)CSc2nc(C(C)C)n[nH]2)C1 +CC(C)COc1cccc(CNC(=O)NCc2ccccn2)c1 +Cc1c(C(=O)NC2CCC(C)CC2)nnn1-c1ccc(Cl)cc1 +O=C(Nc1ccc2c(c1)CN(C(=O)C1CC1)CC2)c1ccccc1F +CN(Cc1cccc(C#N)c1)C(=O)c1ccc(Br)cc1O +CS(=O)c1ccc(NC(=O)NCc2cc(Cl)ccn2)cc1F +Cc1c(F)cccc1NCC(=O)Nc1ccnn1C1CCCC1 +COc1cccc(CNC(=O)COC(=O)c2ccoc2)c1 +Cc1cc(CNc2ccc3[nH]ncc3c2)ccc1F +Nc1cc(N)nc(SCC(=O)c2ccc3c(c2)OCCO3)n1 +COC(=O)C1CN(C(=O)c2ccccn2)CC1c1ccc(F)cc1 +COC(=O)c1ccc(C(=O)Nc2nnc(-c3csc(C)n3)o2)cc1 +CC1(c2cccs2)CC1CNC(=O)c1ccncc1Cl +N#Cc1cc(Sc2ccccc2)c(N2CCOCC2)cc1C#N +Cc1ccncc1NC(=O)NCCOc1cccc(Cl)c1 +CC(C)Oc1nc(-n2cc(Br)cn2)ccc1N +COc1ccc(CCC(=O)NC2CCC(C)CC2)cc1OC +COC(=O)c1cc(CNC(=O)C2CCCO2)ccc1OC +CC(C)(C)NC(=O)CCNC(=O)c1ccc(F)cc1 +O=C(c1ccc2[nH]ccc2c1)N1CCn2cc(Cn3cncn3)nc2C1 +CC(C)COc1ncc(CNC(=O)c2ccoc2)cc1Cl +Cc1c(C(=O)NCc2ccc(F)cc2)c(C)n2cn[nH]c(=O)c12 +COc1cc(OC)c(CNc2cn[nH]c2)c(OC)c1 +COc1cc(CNC(=O)c2cccc(F)c2)cc(OC)c1OC +CC(Sc1ccc(-c2ccc(Cl)cc2)nn1)C(N)=O +Cc1ccccc1S(=O)(=O)CC(=O)N(C)CC1CC1 +COc1ccc(CNC(=O)c2cc(S(N)(=O)=O)oc2C)cc1F +CCCOC(=O)C1=C(C)NC(=O)NC1c1ccc(O)cc1 +CCCOc1cccc(C2NC(=O)c3oc4ccccc4c(=O)c32)c1 +O=C(c1c[nH]c2cccc(F)c12)N(CC1CC1)CC1CC1 +COc1c(C2CCCN2C(=O)c2ccc(C#N)cc2)c(C)nn1C +Cc1noc(CCC(=O)NCC(C)Sc2ccccc2)n1 +N#Cc1ccc(CNC(=O)c2ccccc2NCc2cccnc2)cc1 +Cc1ccc(C(=O)Nc2ccc(N)cc2C)c(C)c1 +COC(=O)c1cccc(NC(=O)c2ccccc2-n2cnnn2)c1 +COc1cccc(-c2ccc(C(C)=O)c(=O)n2C2CC2)c1 +C#CCNC(=O)N1CCC(c2ccc(O)cc2)CC1 +CCN(CCC(=O)OC)S(=O)(=O)N1CCC(C)CC1 +Cc1ccccc1C(=O)NCC(=O)NCCc1ccc(F)cc1 +CC(c1nc2cc(C#N)ccc2n1C)C(F)(F)F +Cc1nn(C)c(C)c1-c1cc(C(=O)NCC2(c3ccccc3)CC2)[nH]n1 +Cc1cc(F)ccc1NCC(=O)Nc1ccc(CC#N)cc1 +Cc1ccc(-c2cc(-c3cccs3)c(C#N)c(N)n2)nc1 +CCOC(=O)C(N)C(O)c1ccc(S(C)(=O)=O)cc1 +CC1(C)CC(c2cn(CCCOc3cccnc3)nn2)CCO1 +CCOc1ccccc1C(=O)N1CCN(C(=O)NCC(C)C)CC1 +CN(CCOCC1CC1)C(=O)c1cccc2cc[nH]c12 +Cc1n[nH]c(-c2cccc(CNC(=O)c3nccnc3N)c2)n1 +COc1ccc(-c2nnc(SCC(=O)OC(C)C)o2)cc1 +O=C(c1ccc2nccnc2c1)N1CCOC2(CCc3ccccc32)C1 +COc1ccc(CNC(=O)COc2ccccc2C#N)cc1OC +NC(=O)c1csc(NC(=O)CSc2ccccc2)n1 +N#CCCN(C(=O)Cc1ccccc1Cl)c1ccccc1 +Cc1nc(N2CCOCC2)ncc1-c1cc(O)n[nH]1 +CCC(NC(=O)c1cncc(-c2cnn(C)c2)c1)C1CCOC1 +COc1ccc(Nc2nc3cc4c(cc3[nH]2)OCCO4)cc1 +Cc1ccc(F)cc1C(=O)NC(C)c1ccncc1 +COCCN(C(=O)Cc1nc2ncccn2n1)C1CCCC1 +COCCNS(=O)(=O)c1cc(-c2cc(C)no2)sc1C +Cc1nc(C)n(C2CCCN(C(=O)C3CC3c3ccccc3F)C2)n1 +CC(=O)N(Cc1ccc(NC(=O)CCC(C)(C)C)cc1)C1CC1 +CC(=O)Nc1cc(C(=O)Nc2ccccc2N(C)C)ccc1C +COc1ccc(C)cc1C(O)CNC(=O)Cc1cccs1 +CCOC(=O)CN(CC)C(=O)C(C)n1cccn1 +CCN(CC)S(=O)(=O)N(C)C1CCC(C)CC1 +CC(=O)Nc1ccc(NS(=O)(=O)c2ccc(F)c(Cl)c2)cc1 +O=C(NCc1noc(Cc2noc3ccccc23)n1)c1ccccc1 +O=C(COc1cccnc1)NC(Cc1ccsc1)c1nccs1 +COc1ccc(-c2nn(C)c3c2C(=O)CC(C)C3)cc1OC +CC(C)c1nnc(NC(=O)N2CCN(c3ccccc3O)CC2)s1 +O=C(NCC(O)c1ccco1)Nc1nnc(CC(F)(F)F)s1 +COc1cccc(C(=O)Nc2ccc3c4c(c(=O)[nH]c3c2)CCC4)c1 +CCOc1cc(C)c(S(=O)(=O)NC(C)CC)cc1C +Cc1cccc2c(=O)c(NC(=O)NCCN3CCOCC3)c[nH]c12 +CCC(C)C(=O)OC(C)c1ccc2c(c1)OCCO2 +O=C(c1ccc(N2CCOCC2)cc1)N(Cc1ccccn1)C1CC1 +CN(Cc1nc2ccccc2s1)C(=O)NCC1CCOC1 +Cc1cc(NC(=O)CN(C)C(=O)c2cccnc2)no1 +COC(=O)C(CC(C)C)NC(=O)c1cnn(-c2ccncc2)c1C +Cc1ccnc(C(NS(=O)(=O)CCCC#N)C2CC2)n1 +CSc1cccc(NC(=O)CCC2Cc3ccccc3NC2=O)c1 +Cc1nc(C(=O)N2CCCC(O)C2)nn1-c1ccc(Cl)cc1 +O=C(c1ccncc1F)N(CC(F)(F)F)C1CCCC1 +Nc1c(-c2ccccc2F)nsc1C(=O)NC1CCCC1 +CCNC(=O)CNC(=O)c1cc(C)nc2c1cnn2C(C)C +CC(C)NC(=O)CNC(=O)Nc1ccc(Cl)c(Cl)c1 +CC(C)(C)OC(=O)CN1CCC(Oc2ccccc2)CC1 +CC(C)(C)NS(=O)(=O)Cc1cccc(C(=O)N2CCCCC2)c1 +CC(=O)N1CCN(c2nc(C)cc(N3CCCC3)n2)CC1 +Cc1csc(-c2c[nH]c(C3CC(=O)N(C4CCCC4)C3)n2)c1 +CC(=O)Nc1cccc(NC(=O)C(C)Nc2ccc(CC#N)cc2)c1 +O=C(Cn1cnnn1)Nc1ccc2c(c1)OCCCO2 +O=C(NCCc1ccccn1)c1cnc2ccoc2c1 +CCOc1ccccc1CCc1nc(-c2ccc(C#N)cn2)no1 +CC1(C)OCC2(CO1)CN(S(=O)(=O)Cc1cccc(F)c1)C2 +COC(=O)C(C)CN(C(=O)c1cccc(OC)c1F)C1CC1 +COc1ccc(OC)c(C2CC(C)Nc3nc(CO)nn32)c1 +COc1ccc(S(=O)(=O)NCCc2cnn(C)c2)c(C)c1 +Cc1ccc(NCC(O)Cn2nnnc2-c2ccccc2)cc1F +CC(C)OCc1ccc(CNC(=O)c2ccco2)cc1 +c1coc(-c2nc(NC3CC3)ncc2-c2cnccn2)c1 +Cc1cc(NC(=O)Cc2cccc(F)c2F)ccc1C(N)=O +OC1CCCN(c2ncc(-c3ccncc3)c(-c3ccoc3)n2)C1 +O=C(CNC(=O)c1sccc1OC(F)F)Nc1cn[nH]c1 +CC(=O)NCC(=O)Nc1c[nH]cc(Br)c1=O +CCOc1ccc(C(=O)NCC(=O)NC2CCCCC2C)cc1 +CCC(OC(=O)CCC(=O)N1CCOCC1)c1ccc(F)cc1 +Nc1nc(COC(=O)C2CC=CCC2)nc2ccccc12 +O=C(CCNc1nc2ccccc2o1)N1CCOCC1 +CCOC(=O)CC1NCCc2c(OCC)cccc21 +CN(C)S(=O)(=O)c1cccc(Cn2c(=O)oc3ccccc32)c1 +C=CCn1c(N)cc(=O)nc1SCC(=O)Nc1c(C)cccc1C +CCC(C)c1ccccc1OCC(=O)NCc1nncn1C +CC(Sc1nnc(-c2ccco2)n1N)C(=O)NCC1CCCO1 +CCCCN1C(=O)C(C)(C)Oc2cc(CO)ccc21 +COc1cc(N)c(NC(=O)c2ccco2)cc1OC +COc1ccc(N)c2c(C(=O)NC(C)(C)CO)nccc12 +CN(Cc1ccccc1Cl)C(=O)NCCNC(=O)c1cccnc1 +Cc1ccc(C(=O)NCc2ccccc2C2CC2)cc1 +Cc1cccc2cnn(CCC(=O)N(C)Cc3ccccc3F)c12 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(Cl)cc1O +CCS(=O)(=O)N1CC2COCC2(COCc2cccnc2)C1 +Cn1ccsc1=NC(=O)c1cccc2c1OCCO2 +O=C(NS(=O)(=O)N1CCOCC1)c1c[nH]c2ccccc12 +CC1Oc2ccccc2OC1C(=O)Nc1cn[nH]c1 +CC(=O)Oc1ccccc1C(=O)c1cncc(Br)c1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2nc(C)no2)c1C +CCCc1sc(C(=O)NCCOC)cc1CC +COc1cc(CNn2cnnc2)ccc1OCc1ccc(F)cc1 +CN(C)C(=O)N1CCC(C(=O)NCC2CCCO2)CC1 +CCc1nc(CCNC(=O)Nc2cc(C)cc3cccnc23)cs1 +Cc1cc(Br)ccc1OCC(=O)N1CCN(C)CC1 +CCCc1ccc(S(=O)(=O)N2CCN(Cc3ccco3)CC2)cc1 +CCCNC(=O)CCC(O)c1cc(F)ccc1F +CC(C)NC(=O)CN(C)C(=O)c1ccc(Cn2ccccc2=O)o1 +CCCN(CC(=O)OC)C(=O)c1cc(Cl)ccc1Cl +O=C(c1ccc2cc[nH]c2c1)N1CCOCC1C1CC1 +COc1cc(C(=O)NCc2nc(-c3ccccc3)no2)on1 +Cc1n[nH]c(C)c1NC(=O)CSc1nccc(C(F)(F)F)n1 +O=C(C#Cc1ccccc1)Nc1ccn(-c2ncccc2Cl)n1 +CC1CCC(NC(=O)C(C)Nc2cnn(C)c2)CC1 +CC(=O)NC1CCc2cc(S(N)(=O)=O)ccc21 +CC1CC(C(=O)NCCOC(N)=O)CC(C)(C)C1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccoc1 +CCc1nc(C)c2c(n1)N(CCCN1CCOCC1)C(=O)CC2 +O=C(c1ccc2nncn2c1)N(C1CC1)C1CCc2ccccc21 +CN(C)S(=O)(=O)NCC(O)c1ccc(Cl)c(F)c1 +Cc1ccc2ncc(C(=O)NCCc3ccncc3C)n2c1 +CC(=O)Nc1ccc(Nc2nnc(-c3ccccc3)c(=O)[nH]2)cc1 +Cn1cnc(-c2ccc(C(=O)Nc3cnccn3)cc2)n1 +O=C(CSc1nnc(C2CC2)o1)c1ccc2c(c1)OCO2 +NS(=O)(=O)c1ccc(NCc2ccc3c(c2)OCCO3)cc1 +COc1ccc2c(c1)OCC(C1NC(=O)c3ccccc3N1)=C2 +O=C(NC1CC1)c1cccc(-c2cc(=O)cc[nH]2)c1 +OC(CN1CCOCC1)c1ccc(Br)cc1 +COc1nc(N2CCCCC2)nc(-n2nnc(C#N)c2N)n1 +O=C(NCc1ccc(F)cc1)c1ccc(CO)cc1 +CC(O)C(=O)N1CCN(CC2=Cc3ccccc3OC2)CC1 +CC(CC#N)NC(=O)c1cc(Br)ccc1F +COC(=O)c1cccc(S(=O)(=O)N(C)C(C)c2ccccn2)c1 +Cc1nnc(NCCNc2cnccn2)c(C#N)c1C +CC(Oc1ccc(Cl)cc1C(N)=O)C(=O)Nc1cccc(F)c1 +COC1=CC(=O)OC1=Cc1ccc(OC)c(OC)c1 +COc1cccc(CN(C)C(=O)COc2ccc(SC)cc2)c1 +OCc1nc2cccc(F)c2n1Cc1ccccc1F +CCNS(=O)(=O)c1ccc(CCC(=O)N2CCC(C)CC2)cc1 +CN(C)C(=O)CSc1nnc(C(C)(C)C)n1N +CN(CC1CCCC1)C(=O)NCC1CN2CCCCC2CO1 +COCc1ccccc1NC(=O)NCc1cc(C(=O)OC)c(C)o1 +CCC(C)NC(=O)C(C)Sc1nnc(-c2sc(C)nc2C)o1 +Nc1nc(-c2ccc(Cl)cc2)nn1C(=O)c1cccs1 +CC(C)CNC(=O)c1cccc(NCc2cccs2)c1 +COc1cccc(C(=O)NCCOc2ccccc2N)c1 +O=C(CCC(=O)NC1CCCCC1)NCc1ccco1 +Cc1cc(C(=O)NC(C)c2noc(-c3ccc(Cl)cc3)n2)[nH]n1 +Cc1nc(CCNC(=O)C(C)Oc2ccccc2F)cs1 +COc1cccc(NC(=O)CN(C)C(=O)c2ccc(SC)nc2)c1 +Cc1ccc(C(=O)CSc2nnnn2C2CC2)cc1 +CS(=O)(=O)NCC(=O)N1CCCC1C1CCCC1 +CCN1C(=O)CCC12CCCN(C(=O)Cc1ccccc1)C2 +C#CCNC(=O)N(CC=C)Cc1ccc(OC)cc1 +Cc1ccc2nc(NC(=O)c3cc(N)ccc3Cl)sc2c1 +Cc1ccc(S(=O)(=O)NCC(=O)N(C)CCc2ccccn2)cc1 +COCCCCNC(=O)N1CCCC1c1nnc2ccccn12 +CCc1ncc(C(C)(O)c2ccccc2)n1Cc1ccccc1 +CS(=O)(=O)N1CCC(n2cnc3ccc(F)cc3c2=O)CC1 +CN(Cc1nnc2n1CCC2)C(=O)C1Cc2cc(Cl)ccc2O1 +Cc1cc(C)n2nc(C(=O)NCC34CC5CC(CC(C5)C3)C4)nc2n1 +Cc1csc(N2CCN(c3ncnc4[nH]ncc34)CC2)n1 +Cc1ccc(NC2CCN(C(=O)CCc3ccncc3)CC2)nn1 +O=C(NCCCO)c1cnc2sc3c(n2c1=O)CCCC3 +N#Cc1cccc(C(=O)Nc2ccnc3ccnn23)c1 +COC(=O)C1CCCC1NC(=O)Nc1ccc2nc(C)oc2c1 +COCCN(CC(C)C)C(=O)c1cc(C(N)=O)cn1C +N#Cc1cccc(S(=O)(=O)Nc2cnn(-c3ccccc3F)c2)c1 +Cc1noc(C)c1CN(C)S(=O)(=O)c1ccc(C#N)cc1 +COc1ccc(OC)c2c1CN(Cc1csc(C(C)C)n1)CC2O +NC(=O)COc1cccc(C(=O)NC2CCN(CC(F)(F)F)C2)c1 +Cc1ccnn1C(C)C(=O)Nc1cnn(CC2CC2)c1 +COc1ccc(NC(=O)Cn2ccc3c(=O)[nH]ccc32)cc1 +Cc1cc(N2CCCC(c3[nH]ncc3S(C)(=O)=O)C2)ncn1 +CS(=O)(=O)N1CCC(C(=O)N2CCOc3ccc(F)cc32)CC1 +Cc1ccc(CCc2nc3ncc(N)cc3o2)cc1 +Cn1cc(S(=O)(=O)NCCc2ccccc2F)cc1C(N)=O +CN(C)Cc1cc(=O)n2c(n1)CN(Cc1ccncc1)CCC2 +O=C(CSc1ccc(O)cc1)N1CCN(c2ccccc2F)CC1 +CC1CCCCC1NC(=O)Cn1c(=O)n(C)c2ccccc21 +COCCNC(=O)c1cc(-c2ccccc2O)no1 +O=C(COc1ccc(Cl)c2ccccc12)Nc1nncs1 +Cc1ccc(NC(=O)c2ccc(S(=O)C(C)C)cc2)cc1C +O=C(Cn1ccccc1=O)NC1(c2ccccc2)CCCCC1 +CC(C)(C)C(=O)N1CCN(C(=O)Nc2cc(F)ccc2Cl)CC1 +CC(=O)c1ccc(S(=O)(=O)NCc2c[nH]nc2C)cc1 +CC(Sc1ccccn1)C(=O)Nc1ccccc1C(N)=O +OC(Cn1ccnc1-c1ccccn1)c1cccc(Cl)c1 +CCn1cnnc1CNC(=O)NCc1ccccc1F +CCC(=O)NCC(=O)NC(C)(C)c1ccc(F)cc1Cl +O=C(c1scnc1C1CC1)N(Cc1ccoc1)C1CCCCC1 +CC(Nc1cccc(CO)c1)c1ccc(C#N)cc1 +Cc1nc2ccc(C(=O)Nc3nnc(C4CC4)s3)cc2nc1C +COc1ccc(C(O)CCc2nccs2)cc1C(C)C +Cn1ccnc(NC(=O)CC=Cc2cccc(F)c2)c1=O +CCNC(=O)NCc1cccc(Cn2cccn2)c1 +Cc1cccc(C2CCCN2Cc2cnc(C3CCCC3)s2)n1 +CCCNC(=O)Nc1cccc(OC(=O)C2CC3CCC2O3)c1 +COc1ccc(C(=O)Nc2cccc(OCC(N)=O)c2)c(F)c1 +Cn1cc(-c2nc(CN3CCc4ccccc43)cs2)cn1 +Cc1nnc2ccc(-c3cccc(NC(=O)C4CC4)c3)nn12 +Cc1ccc(C)c(NC(=O)C(N)c2ccccc2)c1 +O=C(NC1CCCc2c1cnn2-c1ccc(F)cc1)c1ccncc1 +CCN(CC1COc2ccccc2O1)C(=O)NC1CCC(O)CC1 +CC(C)(NC(=O)C1CC(=O)N(c2cccc(Cl)c2)C1)C(N)=O +CCC1C(=O)Nc2c1cc(F)cc2C(O)c1cccc(C)c1 +CCC1(NC(=O)CNC(=O)c2ccc(C#N)cc2)CCC1 +CC(=O)c1cccc(NC(=O)Cn2nnc(-c3ccc(C)cc3)n2)c1 +CC(C)c1noc(C(C)N2CCN(c3ccc4nnnn4n3)CC2)n1 +O=C(NCCCn1ncc2ccccc21)c1ccccc1 +O=C(c1cccnc1OCC(F)F)N1CCC(c2ccccc2)C1 +COC(C)(CNC(=O)c1ccc(F)cc1)c1ccccc1F +Cc1cc(C)c2c(c1)N(C(=O)c1csnn1)CCC2 +N#Cc1c(NC(=O)CSc2nnnn2C2CC2)sc2c1CCC2 +Cc1ccn(Cc2nnc(C(C)C)n2C)c(=O)c1C#N +CC(C)C1Oc2cc(N)ccc2N(CCCO)C1=O +CC(C)c1ccccc1OCCCc1nc(CO)cs1 +O=C(NCc1ccc(-n2cccn2)nc1)c1cc2c(cc1O)OCO2 +CC(=O)c1c(C)nn2c3c(cnc12)C(=O)CC(C)C3 +Cc1csc(C2CCCN(S(C)(=O)=O)C2)n1 +Cc1noc(CSc2ccccc2C(=O)N2CCNC(=O)C2)n1 +O=C(CCC1CCCCC1)NC1CCCc2ncncc21 +COCCN(CC(C)C)C(=O)c1cc(=O)c2ccccc2o1 +Cc1cc(NC(=O)NCC2Cc3ccccc3O2)n(C)n1 +CCCC1CN(C(=O)CCc2cnn(-c3ccccc3)c2)CCO1 +COc1ccc(C(C)NC(=O)CCn2cncn2)cc1OC +CCOc1ccnc(N2CCN(C(C)c3nc(C)no3)CC2)n1 +CN(C)C(=O)CCCC(=O)Nc1ccccc1OC1CCCC1 +Cc1nnc2n1CCN(c1nc(-c3cccs3)nc3ccccc13)C2 +O=C(c1ccc2cccc(F)c2n1)N1CCN(C2CCOCC2)CC1 +Cc1ocnc1CNC(=O)Nc1cnc2c(c1)c(C)nn2C +CCN(CCc1ccccc1)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +CCC(=O)Nc1ccc(C(=O)N2CCOCC2)cc1 +Cc1ccc(NC(=O)NCCOCC(F)(F)F)c(Cl)c1 +CCn1c(NC(=O)c2ccc(C)cc2)c2ccccc2nc1=O +O=C(Cc1ccc(Cl)cc1)NCCc1csc(N2CCCC2)n1 +COc1ccc(OCc2cc(C#N)ccc2F)c(N)c1 +N#Cc1ccc(COC(=O)c2ccc(S(N)(=O)=O)cc2)cc1 +CC(=O)Nn1ccc2c(nnc3c(-c4ccccc4)cnn32)c1=O +O=C(c1ccc(-c2noc(C3CCC3)n2)cc1)N1CCCC1 +CC(C)Oc1ccc(CNC(=O)N2CCOCC2C2CC2)cc1 +CNc1nc2c(=O)n(C)c(=O)n(C)c2n1C(C)C +COc1ccc(C)cc1NC(=O)CSc1nc(C)cc(N)n1 +Nc1nn(Cc2ccccc2)cc1C(=O)N1CCCCC1 +COc1ccc(C(C#N)NCC(F)(F)F)cc1OC +COc1cc2c(cc1O)CCN1Cc3c(ccc(OC)c3OC)CC21 +COc1ccccc1NCC(=O)N1CCN(c2cccc(C)c2)CC1 +O=C(OC(C(=O)N1CCCC1)c1ccccc1)c1ccccc1O +O=C(Nc1ccccn1)c1cnn(-c2ccccc2)c1-n1cccc1 +Cc1cc(C)c(S(=O)(=O)N2CCOCC2)cc1C +Cc1cc(F)ccc1C(=O)NC(CCO)c1ccccc1 +Cc1nc(N)c2sc3nc4c(cc3c2n1)COC(C)(C)C4 +NS(=O)(=O)N1CCCN(C(=O)C2CC2c2cccc(F)c2)CC1 +O=C1CN(C(=O)C2CCCN(c3nc4ccccc4s3)C2)CCN1 +COc1ccc(NC(=O)c2ccc(CNC(C)=O)s2)c(Cl)c1 +Cc1cc(NC(=O)CSc2nc3ccccc3c(=O)n2C)[nH]n1 +COCCN1CCCC2(CCN(c3nnc(C(C)C)s3)C2)C1=O +Cc1ccc(OCC#CCNC(=O)COc2ccc(F)cc2)cn1 +Cc1ccc(S(=O)(=O)Oc2cccc(CC(N)=O)c2)c(C)c1 +O=C(c1cnc2ccccc2n1)N(CCc1cccs1)C1CC1 +O=C(c1sccc1-n1cnnn1)N1CCc2cc(F)ccc2C1 +COc1ccc(Cl)cc1Nc1ncccc1C(N)=O +Cc1cc(C(=O)N2CC(C(=O)NCc3ccc(Cl)cc3)C2)no1 +O=C(Nc1cnc2ccccc2c1)c1ccccc1-c1ncc[nH]1 +O=C(Nc1ccc2ccccc2n1)c1cc(Cl)c[nH]1 +COc1cccc(CNC(=O)COc2ccccc2NC(C)=O)c1 +Cc1ccc(-c2nc(C)c(CCO)s2)cc1F +Fc1ccccc1NCc1nnnn1-c1ccccc1 +COCc1cccc(CNS(=O)(=O)c2cc(F)cc(F)c2)c1 +CN(Cc1c(F)cccc1Cl)C(=O)CNC(=O)C1CC1 +N#CC(CN1CCOCC1)c1ccc2c(c1)CCCC2 +Cc1noc(C)c1CC(=O)Nc1cccn2ncnc12 +CN(C(=O)c1ccc(Br)c(N)c1)c1ccccc1 +CCC(=O)Nc1ccc(C)c(NC(=O)CN2CCCCC2=O)c1 +O=C(NCc1cccc(C(F)(F)F)c1)c1cn2cccnc2n1 +CNc1ccnc(C(=O)Nc2ccc(Cl)cc2Cl)c1 +Cn1cc(N2C(=O)CC3C2CCN3C(=O)c2cccc(F)c2)cn1 +COc1cccc(C(NC(=O)N2CCCCCC2)c2nccn2C)c1 +CNC(=O)CSc1nnc(-c2ccccc2O)n1C +CSc1cc2c(cc1NC(=O)N1CC(C)OC(C)C1)OCCO2 +COc1cccc(Nc2ccc(N)cc2C#N)c1OC +Cn1ccnc1COc1ccc(NC(=O)CCC2CCCO2)cc1 +Cc1noc2nc(-c3ccccc3)cc(C(=O)Nc3ccn(C)n3)c12 +Cc1sc2ncnc(SCC(N)=O)c2c1C +COC(=O)CNC(=O)C(C)Oc1ccc(C(C)(C)C)cc1 +CCOc1cc(CNC(=O)c2ccc(C)nc2)ccc1OC +O=C1CC(C(=O)NCc2ccco2)Oc2ccc(F)cc21 +O=C(NCc1nc2ccccc2[nH]1)c1ccc2[nH]nnc2c1 +Cc1csc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)n1 +Cc1cccc(-c2n[nH]cc2C(=O)N(C)Cc2noc(C(C)C)n2)c1 +COC(=O)CC(NC(=O)c1ccccc1Cl)c1ccc(OC)cc1 +CC(C)OCCC(=O)N1CCCC1c1cccc(F)c1 +COc1cccc(CCC(=O)Nc2nc(C)c(C(C)=O)s2)c1OC +Cc1cc(C)cc(CCNC(=O)c2cc(C)nc3c2c(C)nn3C)c1 +O=C(COC(=O)c1cnccn1)Nc1ccccc1C(F)(F)F +CCC1Oc2ccccc2N(CC(=O)NC(C)(C)C)C1=O +CC(C)C(NC(=O)c1ccc[nH]1)c1nc2ccccc2[nH]1 +Cc1nc(N)nc(C(C)Oc2ccc(Cl)cc2Cl)c1C(N)=O +Cc1ncsc1C(=O)N1CCOCC1CC(=O)c1ccccc1 +Cc1nc(-c2cnn(C)c2)sc1C(=O)OCc1nncn1C1CC1 +Cc1ccc(CN2C(=O)C(C)(C)Oc3cc(O)ccc32)cc1 +Cc1ccc(NC(=O)COc2cccc(-c3noc(C)n3)c2)cc1 +CCOC(C)c1noc(CNc2ccc(Br)c(C)c2)n1 +O=C(Nc1ccc(OCC2CCCO2)cc1)c1c(O)cc(F)cc1F +Cc1ccc(NC2c3ncccc3C(=O)N2Cc2ccco2)cc1C +Cn1nc(C(=O)NCCc2ccc(Cl)cc2)c2ccccc2c1=O +COc1ccc(C(CO)Cc2ccccn2)cc1OC +CCn1cnc2cc(NC(=O)C3CCCC3)ccc21 +CC(C)CN(C)C(=O)c1ccc(NS(C)(=O)=O)cc1 +CCCc1nc(Cn2nc(C)nc2C2CCCCC2)no1 +CC(C)OCCSc1nnnn1-c1ccccc1 +Cc1ccc(-c2nc3c([nH]2)c(C)nn3C2CCCC2)o1 +CCOc1ccc(NC(=O)c2c(C)nn(C)c2C)cc1 +Cc1nc2ccc(NC(=O)c3ccncc3)cc2s1 +Cc1ccc(C(=O)OCc2ccc(C(N)=O)cc2)cc1 +COC(=O)c1cc(N2CCOCC2)ccc1NC(=O)c1ccoc1 +Cc1ccc2c(c1)NCC(=O)N2CC(=O)OC1CCCC1 +Cc1ccc(C(N)=O)cc1NC(=O)NCCC(=O)N(C)C +Cc1nc2sc(C(=O)NC3CCC(C)CC3)c(C)c2c(=O)[nH]1 +CC(C)c1ncc(CN(C)C(C)c2cccc(O)c2)s1 +COc1cccc(S(=O)(=O)CC(=O)Nc2ccc(C)c(F)c2)c1 +N#Cc1ccc(O)c(NC(=O)c2ccc(-c3cscn3)cc2)c1 +O=C(CSc1ccc(Br)cc1)N1CCOCC1 +CC(C)n1ccc(C(=O)N2CCN(C(=O)NC3CCCCC3)CC2)n1 +COc1ccccc1S(=O)(=O)CC(=O)N(C)C1CC1 +CCC(=O)Nc1cccc(NC(=O)NCc2nnc3ccccn23)c1 +COc1ccc2nnc(CCCC(=O)NC3CCOC(C)(C)C3)n2n1 +Cc1cccc(C)c1NC(=O)NCc1nc(-c2ccccc2)cs1 +CCc1onc(C)c1NC(=O)c1ccc2ccccc2n1 +c1ccc2c(CN3CCC(N4CCOCC4)CC3)cccc2c1 +CN1CC(NS(=O)(=O)c2ccccc2OC(F)(F)F)CC1=O +c1ccc2c(c1)NCCN2CCOc1cccc2cccnc12 +Cc1ccccc1NC(=O)Cn1c(C)cc(=O)c2cccc(C)c21 +CCOC(=O)N1CCN(c2nc(N(CC)CC)cc(C)c2C#N)CC1 +COCCOCC(=O)N(C)C(C)c1ccc(Cl)cc1 +CC(C)C(NC(=O)c1cc(F)c(F)c(F)c1)c1nnc2ccccn12 +Cc1ccc(Cl)cc1S(=O)(=O)Oc1ccccc1C(N)=O +CC(NC(=O)c1ccccc1)C(=O)N1CCC(CC(N)=O)CC1 +CCC(C)Sc1nnc(Cc2cccs2)o1 +Cc1csc(=O)n1CCC(=O)N1CCN(C(C)C)CC1 +O=c1c2cccn2cnn1Cc1ccc(F)c(F)c1 +CC(C)(C)Oc1cc(CNC(=O)Nc2ccsc2)ccn1 +CCCS(=O)(=O)c1ccccc1C(=O)Nc1ccccc1 +COc1ccc(NC(=O)C(C)C)cc1OC(F)F +Cc1noc(N)c1C(O)(c1nccn1C)C(F)(F)F +N#Cc1ccc(-c2noc(C3CC3c3cccc(Cl)c3)n2)nc1 +NC(=O)N1CCCN(C(=O)CCSc2ccccn2)CC1 +COCCN(CC(=O)Nc1ncc(C)s1)C(=O)c1ccccc1 +O=C(Nc1ccc2nc(CO)[nH]c2c1)c1ccccc1Cl +CCOc1ccc(NS(=O)(=O)c2ccc(O)cc2)cc1 +CC1CCCCC1NC(=O)CSc1nnc(Cn2cncn2)o1 +CCCn1c(=O)c2ccccc2n(Cc2ccc(F)c(F)c2)c1=O +CCC(O)CN(CC(=O)NC1CCN(C(C)=O)CC1)c1ccccc1 +Cc1cccc(OCc2nc3ccccc3n2CC(=O)NC2CC2)c1 +CCc1nnc(N2CCN(c3ccc(C(C)=O)cc3)CC2)o1 +Cc1csc(NC(=O)c2c[nH]nc2-c2ccccc2F)n1 +O=C(Nc1ccccc1C(=O)NC1CC1)c1cc2cccn2cn1 +CC(=O)c1cnc(NC(=O)c2scnc2C2CC2)s1 +CC(=O)Nc1ccc(C(=O)CSc2nccn2C)cc1 +CC1CCC2(CC1)OCC(CNC(=O)CCn1cccn1)O2 +COc1ccc(Cl)cc1C(=O)c1ccc(N)cc1 +CC(=O)N1CCNCC1c1cccc(C(=O)N(C)C)c1 +CS(=O)(=O)N1CCCc2ccc(NC(=O)c3cccs3)cc21 +Cc1cc(NCC(O)C(F)(F)F)n2nccc2n1 +CCC(C)NC(=O)c1ccc(Cn2cncn2)cc1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cc(F)c(F)cc1Cl +CCC(=O)Nc1ccc(S(=O)(=O)N2CC(C)CC(C)C2)cc1 +Cc1nn(C)c(C(=O)NCCCN2CCOCC2)c1Br +Cc1nn(-c2ccccc2)c(C)c1C(=O)NCc1cccnc1 +C=Cc1nnc(C(N)c2cccc(Cl)c2F)o1 +Cc1c(C(=O)N2CCN(Cc3ccncc3)CC2)oc2ccccc12 +CC(=O)c1ccc(C#CCNC(=O)c2cccn(C)c2=O)cc1 +O=C(Nc1cnn(Cc2ccc(F)cc2)c1)C1CC1c1ccccc1 +COCC1CN(Cc2cccs2)Cc2cn(CC3CCCC3)nc21 +Cc1nn(C)c2nc(-c3cccnc3)nc(NCC(N)=O)c12 +CC1CCN(S(=O)(=O)N2CCOC(c3ccc(F)cc3)C2)CC1 +CNC(=O)c1cccc(OCC(=O)Nc2cc(C)on2)c1 +Cc1ncc(C(=O)N2CCCC2c2c(C)nn(C)c2C)s1 +CCCOc1ccccc1OCC(=O)NC(C)(C)C +CCCS(=O)(=O)NCc1ccc(Oc2ccc(F)cc2)nc1 +O=C1CC(C(=O)N2CCOC3(CCCC3)C2)CN1Cc1ccccn1 +COCCNc1nc(Nc2ccc(Cl)cc2)c2cnn(C)c2n1 +Fc1cc(Cl)ccc1-c1nccn1CC1CCCO1 +Cn1c(=O)c2c(ncn2Cc2cccc(Cl)c2)n(C)c1=O +CC(C)Cc1nn2c(CO)c(-c3ccc4c(c3)CCC4)nc2s1 +COc1ccc(C)cc1CCNC(=O)c1ccc(C(=O)N(C)C)cc1 +CC(NS(C)(=O)=O)C(=O)Nc1ccc(Oc2ccccc2)cc1 +CCC1CCC(CNC(=O)c2cnc(C3CCCO3)s2)CC1 +CC(C)(C)OC(=O)N1CCC(n2c(CO)nc3cccnc32)CC1 +CCNC(=O)COc1ccc(Br)cc1Cl +CCOc1cccc(OC)c1-c1cc(CO)c(=O)n(CC)n1 +CC1CCCN(S(=O)(=O)NC(C)Cc2ccco2)C1 +CN1CC(NC(=O)c2sccc2OC(F)F)CC1=O +CCN(CCC(=O)OC)C(=O)Cc1c(C)nn(C)c1C +COc1ccc(OCC(=O)NCC2CC2)c(N)c1 +COc1ccc(C(=O)CCC(=O)NCc2ccc(C#N)cc2)cc1 +Cc1ccc(C2CC(=O)c3cnc4nc(C)nn4c3C2)cc1 +Cc1ccc(C(=O)N2CC3CC(NC(=O)c4cccs4)C2C3)s1 +COCCNC(=O)C1CC2C(CCN2Cc2ccoc2)O1 +Cc1cnc2oc(-c3ccc4c(c3)OCO4)nc2c1 +N#CCn1c(C(N)c2ccccc2)nc2cc(F)ccc21 +Cn1nnnc1SCC(=O)c1ccc(NC(=O)c2ccco2)cc1 +CCOC(=O)c1sc(NC(=O)c2cc(C)n(CC)n2)cc1C +Cc1ccc(C(NC(=O)c2ccc(CNC(N)=O)cc2)C2CC2)cc1 +COc1c(S(=O)(=O)NC2CCCC2)cc(C)c(C)c1N +c1ccc(C2COC(C3NC(c4ccccc4)CO3)N2)cc1 +CCc1ccc(CN(C(=O)c2ccc(NC(C)=O)cc2)C2CC2)cc1 +Cc1ccc(S(=O)(=O)NCC2CCCO2)c(C)c1 +O=C(NCC1CCOC1)c1cc(-c2ccc(F)cc2)[nH]n1 +CC(C)NC(=O)CN(C)C(=O)CCOc1ccccc1F +CCOC(=O)C1CCCN(c2nc[nH]c(=O)c2N)C1 +COCc1nnc(SCCC(C)C)n1-c1ccccc1 +CCNC(=O)CNC(=O)c1ccc(OC2CCCC2)c(OC)c1 +Cc1ccc2nc(C)c(C(=O)N3CCN(C(=O)C4CC4)CC3)cc2c1 +O=C(CSc1nnc(-c2ccccn2)o1)Nc1cccc(Cl)c1 +CCCC1CN(C(=O)C2CCCN2C(=O)c2cccs2)CCO1 +Cc1ccsc1C(=O)Nc1sc(C(C)C)cc1C(N)=O +C=C(C)CN(CC)C(=O)Cc1cn2ccsc2n1 +CC=CCCNC(=O)NCc1cccc(NC(C)C)c1 +CCCn1nnnc1COc1ccc(Cl)cc1C(N)=O +CN(C(=O)CNc1cc(S(C)(=O)=O)ccc1F)c1ccccc1 +CCCCS(=O)(=O)NCC(=O)N(C)c1ccc2c(c1)CCO2 +O=C(Cn1cnnn1)N(Cc1cccnc1)CC1CCCO1 +O=C(NCc1ccc2c(c1)OCCO2)c1ccc(-n2cccn2)cc1 +NC(=O)C1CCN(c2ncnc3sccc23)CC1 +O=C(NCCO)c1cc(-c2ccc(Br)cc2)on1 +O=C(c1ccsc1)N1CCC(Oc2ccccn2)CC1 +CCCCn1c(NC(C)CC)nc2c1c(=O)[nH]c(=O)n2C +COc1ccccc1N1CCN(C(=O)c2c[nH]c3ccccc23)CC1 +Nc1cc(Br)c(OC(F)(F)F)c(Br)c1 +COC(C(=O)N1CCCC(C(=O)N(C)C)C1)c1ccccc1 +O=C(NCC1(c2ccccc2)CCCC1)c1ccncc1F +Cc1ccc(Oc2ccc(C(=O)N3CCC(C(N)=O)CC3)cc2)nn1 +CN(C)C(=O)CSc1nnc(-c2ccccc2)n1-c1ccccc1 +Cn1c(CNC(=O)C(c2ccccc2)n2cnnn2)nc2ccccc21 +Cc1cnc(-c2nnc(C3CCN(Cc4ccccc4)C3)o2)cn1 +CCOc1ccccc1OCCc1ncc(C(C)(C)O)s1 +CN1CCN(C(=O)c2ccc(=O)n(C)c2)Cc2ccccc21 +CC(NC(=O)c1cccc(Cl)c1)c1ccccn1 +CCCCn1nc(NC(=O)COC)c2cc3ccc(C)cc3nc21 +O=C(Nc1ccc(-n2cnc3ccccc32)cc1)c1cc(C2CC2)[nH]n1 +COc1cccc(C(=O)N2CCOCC2c2ccc(C)o2)c1 +NC1=NC(=O)C(Cc2ccccc2F)(c2cccs2)N1 +CC(=O)Nc1ccc(NC(=O)CCC(=O)c2ccc(C)s2)cc1 +NC(=O)Cc1ccccc1NC(=O)C1CC2C=CC1C2 +Fc1ccc2c(c1)C(Nc1ncccn1)CCCO2 +CS(=O)(=O)Nc1ccccc1CNC(=O)CCc1cccs1 +CCNC(=O)CCNS(=O)(=O)c1c(C)c(C)c(C)c(C)c1C +CCOC(=O)c1ncn2c(=O)n(-c3ccc(C)cc3)nnc12 +CCCc1ccc(C(O)CCC(=O)N2CCCCC2)cc1 +Cc1ccc(S(=O)(=O)c2ncccc2CNCCO)cc1 +COc1cc(F)c(C(C)NC(=O)c2ccccc2O)cc1OC +OCCc1csc(COc2ccc3ccccc3c2)n1 +CC(=O)c1cccc(C(=O)OCC(=O)Nc2cccc(C)c2)c1 +COC(=O)c1ccc(S(=O)(=O)NC(C)Cc2ccco2)cc1 +Cc1csc(=O)n1Cc1ccc(F)cc1Br +COCc1ccc(SC(C(N)=O)c2ccccc2)cc1 +COc1ncccc1NC(=O)NC(C)Cn1cncn1 +N#Cc1cc(F)ccc1COc1ccccc1C#N +O=C(C1CCOC1)N1CCCC(c2[nH]ncc2Cc2ccccc2)C1 +CC(NC(=O)N1CCC(C(=O)c2ccc(O)cc2)CC1)C1CCCO1 +Cc1cnc(NCc2ccccc2OC(C)C)s1 +COCC1CCCN(C(=O)NCC(C)(C)c2ccncc2)C1 +CC(C)(C)OC(=O)N1CCC2(CC1)CC(CO)C2 +Cc1cc(C)cc(C(=O)NCCNS(C)(=O)=O)c1 +Cc1ccc(C(=O)N2CC=C(c3ccccc3Cl)CC2)nc1 +Cc1ccc(NCc2ccc(C(N)=O)cc2F)cc1Cl +C#CCOC(=O)C1CC(=O)N(c2ccc(C)cc2)C1 +Cc1ccnn2c(C(=O)Nc3ccc(F)cc3)nnc12 +CCOC(=O)c1n[nH]c2c1CCN(C(=O)OC(C)(C)C)C2 +O=C(CC1CCCC1)N1CCN(CC(O)c2ccco2)CC1 +c1cc2nnnn2nc1N1CCCC1c1nnc2n1CCCCC2 +Cc1ccccc1CC(=O)Oc1cccc2[nH]ncc12 +O=C(Nc1nnc(-c2ccccc2)o1)c1ccco1 +CS(=O)(=O)N1CCCCC12CCN(c1nncs1)CC2 +CC(C)Oc1ccccc1NC(=O)Cn1cc(N)cn1 +Cc1cn2cc(NC(=O)CCNC(=O)OC(C)(C)C)ccc2n1 +Cc1ccc2c(N)c(-c3nc4ccccc4[nH]3)sc2n1 +CC(C)NS(=O)(=O)c1ccc(C(C)(C)C)cc1 +O=C1CCSc2c1cccc2C(=O)NCCCN1CCOCC1 +Cc1cc(C)nc(Sc2ccc(Cl)cc2C#N)n1 +O=c1ccc(-c2nc(-c3ccncc3)no2)nn1CCc1ccccc1 +O=C(c1ccccc1Cl)N1CCN(Cc2nc(C3CC3)no2)CC1 +Cn1nnnc1SCCc1ccccc1Cl +C#CCN1C(=O)C(Cc2ccccc2OC)Oc2ccc(N)cc21 +Cc1nc2cc(N)ccc2n1Cc1cccc(F)c1 +CC(=O)NC(C(=O)Nc1cc(C)nn1C)C(C)C +CCCC(=O)N1CCCC(C(=O)NCC(O)c2ccc(F)cc2)C1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)Nc1cnn(CC(N)=O)c1 +CS(=O)(=O)NC1CCCN(C(=O)c2ccc(-n3ccnn3)cc2)C1 +CN1C(=O)CC(NCc2ccncc2)C1c1ccc(Cl)cc1 +Cc1ccc(OC(C)C(=O)Nc2ccc(-n3cnnn3)cc2)cc1C +CC(=O)N1CCCC1C(=O)NCCOc1c(C)cccc1C +COCCn1cncc1Cn1cnc(-c2ccccc2)c1C=C(C)C +O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1cc(F)cc2[nH]cnc12 +O=c1[nH]c(CN2CCN(c3ncccn3)CC2)nc2ccccc12 +Cc1ccc(C(C)NC(=O)NCc2cn(-c3ccccc3)nn2)cc1 +CCc1onc(C)c1NC(=O)CNC(=O)c1cccc(Cl)c1 +Cc1c(Cl)cccc1NC(=O)c1cc(-c2ccncc2)[nH]n1 +c1cn(Cc2ccc(OCC3CCCO3)cc2)cn1 +CC(C)CNC(=O)CSc1nnc(CN2CCCCCC2=O)o1 +COc1cc(OC)cc(C2CCN(C(=O)c3cn[nH]c3C)C2)c1 +O=C(Cc1ccc[nH]1)N(Cc1ccc(C(F)(F)F)cc1)C1CC1 +CCC(C)Sc1nnc(COc2ccc(F)cc2)n1N +C#CCNC(=O)NC1CCN(S(=O)(=O)CC)CC1 +CC(=O)N1CCN(C(=O)NCCc2ccc3c(c2)OCCO3)CC1 +CCOc1ccc(NC(=O)Nc2ccn(CCOC)n2)cc1 +Cc1ccc(C(=O)N(C)C)cc1OC(=O)c1cc(C(C)(C)C)n[nH]1 +COC(=O)C1CCCN1C(=O)CCc1nc(C)no1 +CC(=O)c1ccc(NC(=O)C2CC(=O)N=C(N3CCOCC3)N2)cc1 +CCCCN(C)C(=O)Nc1cccc(C(=O)NC2CC2)c1 +CCn1ccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)n1 +COC(=O)CNc1cc(NC(C)=O)c(F)cc1F +CN(C)c1nc(CNc2ccc(NC(=O)C3CC3)cc2)ns1 +CCc1noc(C)c1NC(=O)Nc1ccc2oc(C)nc2c1 +CCc1nc(CCNC(=O)Cc2c[nH]c3c(C)cccc23)sc1C +CC(C)CC(=O)N1CCCc2cc(C(=O)CN)ccc21 +CCc1cc(NCCCn2nc3n(c2=O)CCCC3)n2ncnc2n1 +Cc1ccc(C)c(NS(=O)(=O)c2cccc(S(N)(=O)=O)c2)c1 +NC(=O)Cc1csc(NC(=O)Cc2ccccc2Cl)n1 +CCOc1cccc2c1C(c1ccncc1)NCC2 +COc1ccccc1S(=O)(=O)Nc1cccc(Cl)c1N(C)C +N#CCCNS(=O)(=O)c1ccc(C(=O)OC2CCCC2)cc1 +O=C(CCn1cncn1)NCC(=O)Nc1nccs1 +CC(=O)Nc1cccc(NC(=O)Nc2cccc(-c3nnco3)c2)c1 +Cc1nc2cc(F)ccc2cc1C(=O)N1CCN(CCO)CC1 +CC(C)C(=O)c1ccc(S(=O)(=O)NCCO)cc1 +O=C(CSc1nnc2[nH]c3ccccc3n12)c1ccco1 +COC(=O)COc1ccc(S(=O)(=O)N(C)C2CCCC2)cc1 +CCOC(=O)c1cc(-c2ccccn2)nn1-c1ccc(Cl)cc1 +COc1ccccc1C(=O)NCC(=O)Nc1cc(F)cc(F)c1 +CC(=O)Nc1ccc(N2CC(C(=O)NC(C)(C)C)CC2=O)cc1 +Clc1ccc(C2CSc3nnc(C4CC4)n3N2)cc1 +CCN(CC)C(=O)C1CCN(C(=O)NCc2ccccn2)CC1 +Cc1nn(CCCNC(=O)c2ccc3c(c2)OCO3)cc1Cl +CC(C)CC(C)OCCC(=O)N(C)c1ccc(Cl)cn1 +CC(=O)c1ccc(OCC(=O)Nc2ccc(C)cn2)cc1 +CCn1cc(S(=O)(=O)N2CCN(Cc3ccc(C)o3)CC2)cn1 +Cc1cccnc1Nc1cc(C2CCCN(S(C)(=O)=O)C2)ccn1 +CC(=O)c1cccc(S(=O)(=O)NCCCn2cncn2)c1 +COc1ccccc1OCCN1CCNc2ccccc21 +COc1cccc(-n2cnnc2SCC(=O)N(C)C)c1 +COc1cc(C(=O)NCC#Cc2ccccc2F)cc(OC)c1OC +CNC(=O)c1cccc(C(=O)Nc2cccc(Nc3cnn(C)c3)c2)c1 +COC(=O)CCCn1c(C#N)nc2cccc(F)c21 +CCOc1ccc(OC)c(-c2[nH]c3nc4cc(N)ccc4n3c2C)c1 +Cc1nc(C(=O)N2CCOCC2)nn1-c1c(Cl)cccc1Cl +COc1cc2c(c(Cl)c1OC)C(C(O)CO)NCC2 +CNC(=O)c1ccc(Cl)c(NC(=O)c2nc3nccc(C)n3n2)c1 +O=C1CCCCC1Sc1nnc(-c2cccnc2)o1 +Cc1noc(C)c1CCC(=O)N1CCCC1c1c(C)nn(C)c1C +COC(=O)c1nnn(CC(=O)Nc2ccc(OC)cc2)c1N +CN(Cc1nc2ccccc2n1C)C(=O)c1cccc(-c2ccoc2)c1 +N#Cc1nc(NCc2ccc(S(N)(=O)=O)cc2)ccc1Cl +O=C1NC(c2ccc(F)cc2)c2c(-c3ccco3)n[nH]c21 +CC(C)(C)OC(=O)N1CCC(c2cc(N)ccc2F)CC1 +Nn1c(Cc2ccccc2)nn2c(=O)c3ccccc3nc12 +CCc1ccc(-c2csc(NC(=O)c3ccno3)n2)cc1 +COC(=O)CCn1c(-c2ccncc2)nc2cccc(F)c21 +CCOc1cccc(C(=O)Nc2ccc(-c3nncn3C)cc2)c1 +CC(=O)NC(CC(=O)OCc1ccoc1C)c1c(F)cccc1F +O=C(c1ccc2cc(O)ccc2c1)N1CCCCC1 +CCOC(=O)C1CCN(S(=O)(=O)NC2CCC(C)CC2)CC1 +CCC(C)(C)NC(=O)c1cc2c([nH]c1=O)CCCC2=O +CCC(CO)NS(=O)(=O)c1ccc(F)c(Cl)c1 +CCC(C)N(Cc1ccncc1)C(=O)CCn1ccc(=O)[nH]c1=O +Cc1cc(C)c(NC(=O)Cn2[nH]c(=O)c3ccccc3c2=O)c(C)c1 +Oc1ccc2c(c1Cl)C(c1ccncc1)NCC2 +COc1ccc(C(=O)COc2ccccc2N)c(C)c1 +COCCN1C2COCC1CN(S(=O)(=O)c1cn(C)cn1)C2 +COC(=O)c1ccc(NC(=O)COc2ccccc2)cc1 +CC(NC(=O)c1cccnc1)c1ccc(Cl)c(Cl)c1 +COc1ccc(Cl)cc1C(=O)N1CCOCC1C +Cc1nn(C)c(-c2ccc(OC(C)C)c(Cl)c2)c1N +Cc1ccc(C2COCCN2C(=O)c2ccsc2)o1 +CCOc1ccc(F)c(C(=O)NCC(=O)NC2CCCCC2)c1F +COC(=O)C(C)n1c(C(C)C)nc2cccc(F)c21 +COC(=O)CC(NC(=O)c1csnc1C)c1cccc(Cl)c1 +COc1ccc(F)cc1CNC(=O)C(N)Cc1ccccc1 +O=C(COC(=O)C1CCN(c2cnccn2)CC1)NC1CCCCC1 +Cc1ccc(S(=O)(=O)N2CCNC(=O)C2C)cc1 +CN(CC(=O)NCC(=O)N1CCCc2ccccc21)C(N)=O +Cc1[nH]c(=O)ccc1C(=O)N1CCc2cc(F)ccc2C1 +COc1ccc(C(O)C(=O)N2CCCc3ccccc32)cc1 +O=C(c1cncc(F)c1)N(c1cccc2cccnc12)C1CCCC1 +CCOC(=O)c1nc(NC(C)(C)CC)c2c(C)noc2n1 +Cn1cccc1C(=O)NC(C)(C)c1noc(C(C)(C)C)n1 +Cc1ccc(NC(=O)CCn2c(=O)c(C)nc3ccccc32)cc1F +Cc1nc(N2CCCC2)nc(C)c1NS(=O)(=O)Cc1ccccc1 +O=C1CCc2cc(C(=O)NCCCn3cncn3)ccc2N1 +CC(C)CS(=O)(=O)Nc1ccccc1C(N)=O +O=C(Nc1cccc(N2CCOC2=O)c1)c1ccc2ccccc2n1 +COc1cccc(OC)c1C(=O)NCc1ccccn1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccc(F)c(F)c1 +CC(C)Cn1cnc2c1c(=O)n(CCC#N)c(=O)n2CC(C)C +Cc1n[nH]c(-c2ccc(NC(=O)Cc3ccc[nH]3)cc2)n1 +Cn1cccc1C(=O)Nc1ccccc1SC(F)F +Cc1ccn2c(CN(CCC#N)CC3CC3)cnc2c1 +CCCn1c(SCc2ccoc2C(=O)OC)n[nH]c1=O +CCCCN(C)C(=O)c1cc(OC)cc(OC)c1 +Cc1cc(F)ccc1S(=O)(=O)NC1(C#N)CCCC1 +CCc1ccc(S(=O)(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +Cc1nc(C(C)C)c(-c2nn3c(-c4ccco4)nnc3s2)s1 +Cc1cc(C)cc(OCCNC(=O)CN2CCCCC2=O)c1 +CN(Cc1cccc(C#N)c1)C(=O)c1ccc2ccccc2c1O +O=C(NCc1nc2ccccc2n1Cc1ccccc1)C1CC1 +CC(NC(=O)Nc1ccc(Oc2cccnc2)nc1)c1ccncc1 +Cc1ccc(Cl)cc1NC(=O)C(C)Sc1ncn[nH]1 +COCCCOc1ccccc1NC(=O)c1nc2nccc(C)n2n1 +Cc1noc(COCC(=O)OC2CC(C)CCC2C(C)C)n1 +CS(=O)(=O)N1CCC(C(=O)OCc2nccs2)CC1 +CC(=O)c1c(C)[nH]c(C(=O)CSc2nc3ncccn3n2)c1C +N#Cc1ccc(OCCCn2cc(-c3nnco3)ccc2=O)cc1 +CC(C)(C)CNC(=O)c1nnc2ccc3ccccc3n12 +CC(C#N)(NC(=O)CSc1ccc(N)cn1)C1CC1 +CC(C)(C)OC(=O)N1CCCC(C(=O)Nc2nncs2)C1 +O=S(=O)(CC1CCCCC1)Nc1cccc(O)c1 +CC(=O)Nc1cccc2c1CCN(c1nc3ccccc3s1)C2 +CC(C)c1cccc(Cn2ncc3cnn(C)c(=O)c32)n1 +Cc1ccc(C(=O)NC(COc2ccccc2F)C(C)(C)C)c(=O)[nH]1 +Cc1c(CN2CCNC(=O)C2c2ccccc2)cc(C#N)n1C +O=C(Nc1nnc(C(F)(F)F)s1)c1ccnc2ccccc12 +CCCc1ccc(S(=O)(=O)NCC(C)C#N)cc1 +COc1ccc(C(=O)NC2CC2)cc1S(=O)(=O)N(C)C +COc1ccc(C(=O)Nc2ccc(NCC(C)O)nc2)cc1OC +CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)Nc1ccc(Cl)cc12 +Cc1cc(S(=O)(=O)NC(C)c2ccon2)c(F)cc1F +CCn1ccc(NC(=O)CNC(=O)c2ccn(C)n2)n1 +Clc1ccc(CSc2nc3ncccn3n2)cc1 +CC(C)(C)c1cc(C(=O)Nc2cccc3cn[nH]c23)[nH]n1 +O=C(CCC(=O)c1ccc(F)cc1F)Oc1ccccc1F +Cc1ccccc1CC(=O)OCCn1c(=O)oc2ccccc21 +Cc1nc2ncnn2c(C)c1CCC(=O)N1CCC(CC(N)=O)CC1 +COc1nccc2cc(NCc3ccccc3)ccc12 +Cc1ccc2[nH]nc(C(=O)N(C)Cc3cc(C)on3)c2c1 +CNC(=O)c1ccc(Cn2cnc(C3CCC3)cc2=O)cc1 +COc1ccc(C(=O)N(C2CCCC2)C2CC2)cc1-n1cnnn1 +COc1ccc(C(=O)C(C)Sc2nncn2C2CC2)cc1OC +O=C(CCc1cscn1)N1CCCC1c1noc(C2CC2)n1 +CC(CNC(=O)c1cc(C2CC2)nn1C(C)(C)C)N1CCOCC1 +COc1cc(CO)c(Br)cc1OCC(N)=O +Cc1ccc(C)c(COCCOCn2cc(C)c(=O)[nH]c2=O)c1 +CC(C)Cn1c(CCCO)nc2cc(C(F)(F)F)ccc21 +COc1ccc(C2CCC(OC)c3nc(N)nn32)c(F)c1 +O=C1CCC(C(=O)NCC(c2ccccc2)c2c[nH]c3ccccc23)N1 +CC(C)CCNC(=O)c1cnc(-c2ccccc2)nc1 +COc1ccc(C(=O)NCC(O)c2c(Cl)cccc2Cl)nn1 +O=C(Nc1ccc2nc(C3CC3)sc2c1)c1cnns1 +CCC1CN(C(=O)Nc2ccc(F)cc2)CCO1 +CC(C)COC(=O)N1CCC(Cc2nnc(CO)n2C)CC1 +COC(=O)C(NC(=O)Nc1cccc(C(C)=O)c1)C(C)C +CCCN1C(=O)C(C)(C)Nc2cc(F)c(F)cc21 +COc1ccc(Cl)cc1C(=O)N(C)CC1CC1 +O=S(=O)(NCCC(O)c1cccs1)C1CCCCC1 +Cc1cc(NC(=O)Nc2ccc(C(C)C)cc2)n(C)n1 +CC(C)(NC(=O)c1ccncc1F)c1ccc(F)cc1Cl +O=C(NCCc1ccncc1)c1cccnc1Oc1cccnc1 +CCOC(=O)c1cc2ccc(OC(=O)C=C(C)C)cc2oc1=O +N#CCOc1ccc(CNC(=O)c2ccc(F)nc2)cc1 +CC(=O)NCCNS(=O)(=O)C1=Cc2ccccc2CC1 +Cc1sc(-c2nnc(C3CC3)o2)cc1NC(=O)C1CC1 +O=C(Nc1ccc2c(c1)COC2)c1ccc(N2CCOCC2)c(F)c1 +CCOC(=O)c1c(C)[nH]c(C)c1-c1csc(NCC2CCCO2)n1 +CCOC1CC2(CCN(c3cnccn3)CC2)c2ccccc21 +Cc1nc2c(c(N3CCc4ccccc4C3)n1)CCC2 +COc1ccc2c(c1)nc(CC#N)n2Cc1ccc(N)nc1 +N#Cc1ccccc1OCCCS(=O)(=O)c1ccc(F)cc1 +CCC1CCC(NC(=O)Cc2cccc(O)c2)CC1 +Cc1ccccc1C(NC(=O)c1occc1C)c1ccncc1 +CC(OC(=O)C12CC3CC(CC(C3)C1)C2)=C1CCOC1=O +O=C(Cn1ccc2ccccc21)NCc1nc2ccccc2[nH]1 +COc1ccncc1NC(=O)c1ccccc1N(C)c1ccccc1 +CC(=O)c1cc(Br)ccc1OC(=O)c1ccoc1 +O=S(=O)(c1cc(F)cc(F)c1)N1CCNCC1 +Cc1ccc(C(=O)NCC(=O)Nc2cccc3cccnc23)s1 +O=C(Nc1cc(F)ccc1Cl)c1ccc(N2CCCCC2=O)cc1 +Cc1nc(C(=O)N(CCc2ccccc2)Cc2ccncc2)cs1 +CCS(=O)(=O)N1CCC(n2c(COC)nc3cccnc32)CC1 +Cc1ccccc1CC1Oc2cc(O)ccc2N(CCCO)C1=O +COc1cc(OC)c(NC(=O)c2ccccc2C)cc1NC(C)=O +Cc1cc(OC(=O)CCc2cnn(C)c2)cc(C)c1Cl +CCOc1ccc(S(=O)(=O)NCCc2ccoc2)cc1 +COCCOc1ccc(C(F)(F)F)cc1NC(=O)c1ccon1 +COc1ccc(C(O)C(C)NCc2ccco2)cc1 +CC(C)(C)NC(=O)c1ccc(NC(=O)CCc2cccc(N)c2)cc1 +Cc1ccc(NC(=O)NC(CCO)c2ccccc2)cc1Cl +CNc1nc(CNC(=O)Nc2cc(Cl)ccc2N(C)C)cs1 +CC(C)N(C(=O)c1ccc(OCC(F)F)nc1)C1CCOCC1 +Cc1csc(=O)n1CCC(=O)Oc1cccc(-n2cccn2)c1 +O=c1[nH]n(C2CCCCCC2)c2c1C(c1ccncc1)CC(O)=N2 +COc1cccc(CS(=O)(=O)c2nnc(C3CC3)n2C)c1 +Cn1cnnc1S(=O)(=O)C1CCN(C(=O)c2ccsc2)CC1 +Cc1ccc(N2CC(C)N(C(=O)C3CC3)CC2=O)cc1 +O=C(C1CCN(c2ccc(N3CCCCC3)nn2)CC1)N1CCCC1 +CCc1c(C(=O)NCC(C)(C)c2ccncc2)cnn1CC(C)C +COc1ccc(-n2ccnc2-c2nccn2CC(C)(C)OC)cc1 +Cc1noc(C)c1COC(=O)C12CC3CC(CC(O)(C3)C1)C2 +O=C(Nc1cccc2[nH]ccc12)C1CC(=O)N(Cc2ccccc2)C1 +Cc1noc(C)c1C(=O)NC(C)c1ccc2c(c1)OCCCO2 +CC(C)(C)OC(=O)NCCC(=O)Nc1cc(C(F)(F)F)ccc1O +COC(=O)c1cnc(NC(=O)CCNC(=O)c2cccc(C)c2)s1 +COc1ccc(NC(=O)c2ccc[nH]c2=O)cc1Cl +Nn1c(SCc2noc3c2CCCC3)nnc1C1CCCCC1 +COc1cc(OC)cc(C(=O)c2ccc(C)nc2)c1 +CC(=O)NC1CCN(c2ncnc3c2Cc2ccccc2OC3)C1 +N#CCc1nc2ccc(F)c(F)c2n1C1CCCC1 +COc1ccc(NC(=O)CN(C)c2ncnc3[nH]cnc23)cn1 +O=C(NCCCn1cccn1)N1CCCN(CC(F)(F)F)CC1 +CCC(=O)Nc1cccc(-c2nc(C(C)(C)OC)no2)c1 +Cc1nc(SCC(=O)Nc2ccccn2)oc1C +CC(Nc1cc(C#N)c2ccccc2n1)c1nnc2n1CCC2 +O=C(Nc1nnc(C2CC2)s1)c1ccc(-n2cccc2)cc1 +O=C(c1ccncc1Cl)N1CCCC(Nc2ccccc2)C1 +O=C(NCc1ccco1)Nc1ccccc1C(F)(F)F +CC(=O)c1cc(Cl)ccc1OCC(=O)NCC1CCCO1 +C=CCN(C(=O)COc1ccccc1OC)c1ccccc1 +Cn1cnnc1-c1ccc(NC(=O)CCSc2ccccc2)cc1 +Cc1cccc(NC(=O)Nc2ccccc2S(C)(=O)=O)c1C +O=C(Nc1ccccc1C(F)(F)F)NC(CO)c1ccccc1 +COc1ccc(C=Cc2n[nH]c(=O)c(C#N)c2C)cc1O +Cn1ncnc1CNC(=O)Cc1cccc(OCC#N)c1 +CCCCNC(=O)N(CCO)Cc1cccnc1 +O=C(Nc1ccccc1OC1CCCC1)c1cc[nH]n1 +CC1CC2CN(C(=O)CCc3ccccc3)CCC2O1 +NC(=O)C1(CNC(=O)Cn2ccc3ccccc32)CCOCC1 +Cc1ccc(C(=O)Nc2ccc(NC(=O)c3ccco3)cc2)s1 +Cc1cc(CNC(=O)c2c(F)cccc2F)nc(N2CCOCC2)n1 +COc1ccc(O)c(C(=O)N(Cc2cccs2)C2CC2)c1 +CC(NC(=O)c1cn2c(n1)COCC2)c1ccccn1 +CN1C(=O)CCCc2cc(C(O)Cc3cccs3)ccc21 +CCOc1ccc(S(=O)(=O)NCc2ccco2)cc1C +COCCC(=O)N1CC(Oc2ccccc2OC)C1 +c1csc(N2CCCN(c3ncnc4[nH]cnc34)CC2)n1 +CCn1cc(CN2CCCN(c3ccccc3C)CC2)cn1 +CNc1ncccc1C(=O)N1CCN(c2nc(C)cc(C)n2)CC1 +COc1ccc(C(=O)OCC#CCSc2nncn2C)cc1OC +Cc1ccc(CCNC(=O)C2CCC(=O)N(C3CCCCCC3)C2)o1 +O=S(=O)(NCc1ccccc1OC(F)F)N1CCCCCC1 +CC(=O)NC1CCC(Nc2ccc(C)cc2OCC2CCCO2)CC1 +COc1cc(Br)cc(C)c1NC(=O)C(C)OC +COc1ccccc1S(=O)(=O)N(C)Cc1cccnc1 +Cc1ccc(CNc2ccc(F)c(N3CCCS3(=O)=O)c2)cc1 +O=C(COc1ccccc1Cl)Nc1ccccn1 +Cc1cc(C)c(N2CCN(C(=O)OC(C)(C)C)CC2)cc1N +CC(C)NC(=O)c1noc2c1CN(C(=O)NC(C)C)CC2 +CC(=O)c1ccccc1NC(=O)c1c[nH]c2c(F)cccc2c1=O +CCCc1cc(=O)n(CC(=O)Nc2ccc(C)c(F)c2)cn1 +Cc1cc(C(=O)OCc2nncn2C2CC2)ccc1-n1cncn1 +CC(C)c1ccc(C(=O)N2CCc3ccccc32)c(N)n1 +CS(=O)(=O)N1CCC(CNC(=O)c2ccc(F)cc2Cl)CC1 +CC1CCC(N2CCN(S(=O)(=O)Cc3ccccc3)CC2)CC1 +CCC(=O)Nc1nc(-c2ccc3c(c2)CCN3C(C)=O)c(C)s1 +CCOc1ccccc1NCC(O)c1cccs1 +COc1ccc(NC(=O)Cn2c(C)nc3ccccc32)cc1Cl +CC(=O)N1CCC(Nc2cc(F)ccc2SCC(F)F)CC1 +COCc1cc(C)n(CC(=O)Nc2cccc(Cl)c2)c(=O)c1C#N +COc1ccnc(C(=O)NC2CCN(c3c(F)cccc3F)C2)c1 +Cc1ncc(C(C)NC(C)c2cn(-c3ccccc3)nn2)c(C)n1 +CCOC(=O)N1CCCN(Cc2nc3c(cnn3C)c(=O)[nH]2)CC1 +Nc1ccc(C(=O)NCc2ccsc2)cc1F +CC1Sc2ccc(-c3cc(N)no3)cc2NC1=O +O=C(CNS(=O)(=O)Cc1ccccc1)Nc1ccccc1 +Cc1cccc(C(=O)NC(C)C(=O)NC(C)CCC(C)C)c1 +Nc1ccc2c(cnn2-c2ncc(C(F)(F)F)cc2Cl)c1 +CC(c1ccc(S(N)(=O)=O)cc1)N(C)C(=O)c1ccccc1F +CCCNC(=O)CCS(=O)(=O)c1cccc2nonc12 +COCc1cc(C(=O)N2CCN(C)CC2c2ccccc2)ccc1F +CC(C)(C)c1ccc2c(c1)CN(C(=O)C1CCC(=O)N1)CC2 +Cn1nc2n(c1=O)CCN(CC(O)COCc1ccco1)C2 +CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c1ccccc1Cl +CCc1n[nH]c(C2CN(Cc3cn4c(C)cc(C)nc4n3)CCO2)n1 +O=C1CCC(C(=O)N(Cc2ccccc2)Cc2ccco2)N1 +CS(=O)c1nncn1-c1nccc(Oc2ccc(F)cc2)n1 +C=CCn1cnnc1SCC(=O)c1ccc(C)s1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1coc(S(N)(=O)=O)c1 +COc1cc(C2CC3(C)NC(=O)C2C(=O)N3)cc(OC)c1OC +COc1ccc(CN(C)c2c(C#N)nnc3ccccc23)cc1OC +Cc1cccc(C)c1NC(=O)COC(=O)c1c(F)cccc1Cl +Cc1n[nH]cc1CNCc1ccc(OC2CCCC2)nc1 +Cc1oc(-c2ccccc2)nc1CC(=O)NCc1ccccn1 +Cc1cc(C)n(CC2CCCCN2C(=O)c2cnn3cccnc23)n1 +OC(CNCc1cnn(-c2ccc(F)cc2)c1)c1ccc(Cl)cc1 +COc1cccc(OCC(=O)Oc2ccc3cn[nH]c3c2)c1 +Cn1nc2n(c1=O)CCN(CC(=O)NCC1Cc3ccccc3O1)C2 +Nc1nc(-c2ccco2)cc(-c2c(F)cccc2Cl)n1 +COc1cc(Cl)c2c(c1OC)C(C)NCC2(C)C +CN(Cc1ccccc1)C(=O)CNC(=O)c1ccc(N)cc1 +Cc1nnc(SCCSc2ccc(Cl)cc2)n1CC(N)=O +CN(CCCc1cc(-c2ccc(F)cc2)n[nH]1)C(=O)c1csnn1 +COC(=O)c1cccc(NC(=O)N2CCOCC2C2CC2)c1 +Cc1ccc(C(=O)N2CCN(c3ccc(O)cc3)CC2)cn1 +Cc1nn(CC(F)(F)F)c(C)c1Cc1nc(-c2cnn(C)c2)no1 +CCOC(CC)C(=O)N1CCCC(NC(N)=O)C1 +COc1cccc(C(=O)Nc2cc(N(C)C)c(N)cc2Cl)c1 +COc1ccc(NC(=O)NC(C)COc2ccc(F)cc2F)cn1 +Cc1sc2ncnc(N3CCc4nn(C)c(=O)cc4C3)c2c1C +CN(Cc1ccccc1)C(=O)CSc1ccc2c(c1)OCCO2 +O=C(OCc1ccccc1)n1c(=O)oc2ccccc21 +O=C(CNC(=O)c1cc2ccccn2n1)NCCc1ccco1 +COC(=O)Cc1csc(NC(=O)NC(C)C)n1 +O=C(CCc1nc(-c2ccco2)no1)N1CCC2(CCCCC2)CC1 +COc1ccc(NC(=O)c2ccncc2F)cc1Cl +Fc1ccc(Oc2ncccc2-n2cnnc2)cc1 +CCCc1nnc(SCC(=O)Nc2nccs2)n1-n1cccc1 +CC(C)(CNC(=O)CCc1ccco1)c1cccs1 +Cn1c(=O)c2ccc(C(=O)Oc3ccccc3)nc2n(C)c1=O +CC1CCCN(C(=O)C2CCN(C(=O)C3(C#N)CCCC3)CC2)C1 +Nc1ncc(Cc2cccc(Br)c2)c(N)n1 +COc1ccc(OC(C)CNC(=O)c2ccncc2)cc1 +CN(Cc1ccccc1F)C(=O)c1ccc(N(C)C)cc1 +O=C(Cn1ncc2c(N3CCCCCC3)ncnc21)NC1CCCC1 +CN(c1ccccn1)S(=O)(=O)c1cnc(N)nc1 +CCOC(CC)C(=O)N1CCC(Oc2ccc(F)cc2F)CC1 +O=C(NCc1cc(Br)cc2c1OCOC2)c1ccccc1 +O=C(COc1ccc(Br)cc1)NCc1ccccc1F +Cc1cnc(C(=O)Nc2nc3ccccc3[nH]2)cn1 +COc1ccc(OC)c(C2CCN(C(=O)Cc3csc(C)n3)C2)c1 +O=C(Cn1nc(-c2ccco2)ccc1=O)Nc1cccc(F)c1 +Cc1ccc(C(NC(=O)COc2ccccn2)C2CC2)cc1 +O=C1CCC(OCc2ccccc2)N1S(=O)(=O)c1ccccc1 +O=C(Cn1c(=O)cnc2ccccc21)Nc1cccc(Cl)c1F +O=S(=O)(N1CCCCC1)N1CCOC(c2ccc(F)cc2)C1 +CCOc1ccccc1C(=O)NCc1nnnn1-c1ccccc1 +Cc1csc(N2CCN(c3ncnc4[nH]ccc34)CC2C)n1 +CC(c1nc(-c2ccncc2)no1)c1ccccc1F +CCn1c(=O)c2[nH]c(C=Cc3ccc(F)c(F)c3)nc2n(CC)c1=O +COc1ccc(C2CCN(Cc3c[nH]nc3C)C2)cc1 +CCOC(=O)c1cnn2ccn(CCCN3CCOCC3)c12 +COC(=O)Cc1nn(CC(=O)NC(C)C)c(=O)c2ccccc12 +CNS(=O)(=O)c1cccc(CNC(=O)c2ccc(=O)[nH]c2)c1 +CCCN1C(=O)c2ccc(Cl)cc2NC1c1ccccn1 +CCOC(=O)CN(C(=O)c1ccc(CC)s1)C1CC1 +Cc1ccc(C(=O)Oc2cccc3[nH]ncc23)n1C +Cc1cc(NC(=O)CN(C)C(=O)C2CCOC2)no1 +CN(C(=O)CSc1ncnc2c1cnn2-c1ccccc1)C1CC1 +Cc1ccc2nc3c(cc(C(=O)N4CCOCC4)n3C)c(=O)n2c1 +CCCCNC(=O)c1nn(-c2ccc(F)cc2)nc1CO +CN(Cc1cccc2ccccc12)C(=O)c1ccc2c(c1)OCCCO2 +O=C(Nc1ccccc1)C1COc2ccccc2O1 +COc1cccc(-c2noc(C(=O)NCc3cn(C)nc3C)n2)c1 +Cc1ccc(C2CC2C(=O)Nc2ccc3c(c2)oc(=O)n3C)s1 +CCc1ccccc1NC(=O)COc1ccc(C#N)cc1OC +Cc1ccccc1OCCCSc1nnc(N)n1C +Cc1ccc(S(=O)(=O)NCCNC(=O)c2sccc2C)cc1 +CS(=O)(=O)c1cccc(OS(=O)(=O)c2ccccc2Cl)c1 +CC(C)CNC(=O)CNc1ccc(Br)cc1 +CN(C)C(=O)Nc1cccc(-c2nnc3n2CCC3)c1 +Cn1cc(CCC(=O)NC(c2ccccc2)C2CCCC2)cn1 +COc1ccc(NC(=O)c2cccc(NC(N)=O)c2)cn1 +COc1ccnc(C(=O)NCC2(c3ccc(F)cc3F)CC2)c1 +Cc1nc2sc(=Cc3ccc(Cl)cc3)c(=O)n2n1 +COc1cccc(-c2cc(CNC(=O)c3cnc(C)nc3C)no2)c1 +FC(F)(F)Oc1ccc(CSc2nnnn2C2CC2)cc1 +Cc1noc(CCCC(=O)NCc2ccccc2-n2ccnc2)n1 +Cc1ccccc1OCC#CCNC(=O)CCn1ccc(=O)[nH]c1=O +COC(=O)c1cccc(NC(=O)CSc2nnc(C(C)C)n2N)c1 +C#Cc1cccc(NS(=O)(=O)c2ccc3c(c2)CCN3C(C)=O)c1 +COc1ccc(CNC(=O)c2cc(C)nc3c2c(=O)[nH]n3C)cc1F +Cc1cccc(-n2ccnc2SCC(=O)Nc2ccccn2)c1C +Cn1nnc(CO)c1COc1ccccc1Cl +COc1ccc(CNC(=O)COc2ccccc2F)cc1NC(C)=O +Cc1cccc(C)c1NC(=O)CCC(O)c1cccs1 +Cc1nc(C)c(CC(=O)NCC(C)(C)c2ccccc2Cl)c(=O)[nH]1 +Cc1cc(O)ccc1NC(=O)Cc1cccc(F)c1F +Cc1cccn2cc(COC(=O)c3cnn(Cc4ccccc4)c3)nc12 +COc1ccc2c(c1)cc(C(=O)NCCSc1ccccn1)n2C +Cc1nc(-c2ccc(S(=O)(=O)N3CCOCC3C3CC3)cc2)co1 +Cc1ccc(C(C)NC(=O)c2cc(-c3ccccc3)[nH]n2)o1 +Cc1nn(-c2ccccc2)c(C)c1Nc1ncccc1C#N +Cc1n[nH]c(NC(=O)c2cnc(C3CCCO3)s2)c1C +O=C(NCc1ccncc1)Nc1cccc2[nH]ccc12 +COC(=O)N1CCC(NC(=O)c2ccc(-n3cccc3)cc2)CC1 +Cc1ccsc1C(=O)NCc1ccc(COC(C)C)cc1 +Cc1ccccc1OCCNC(=O)c1ccccc1F +COc1ccc(CNC(=O)c2nc(-c3cccc4[nH]ccc34)no2)cc1 +N#Cc1ccc(Cn2nc(-c3ccco3)oc2=O)c(F)c1 +Cc1sc(-c2ccno2)cc1S(=O)(=O)NCCc1ccccc1 +COC(=O)c1cccc(S(=O)(=O)Nc2ccccc2)c1 +Nc1ccc2c(C(=O)Nc3ccc(F)c(F)c3F)nccc2c1 +COc1c(Cl)c(OC)c(OC)c2c1CCNC2 +N#Cc1ccc(-c2noc(CCNC(=O)Cc3ccccc3)n2)nc1 +CC(C)(C)c1ccc(OC2CC2)c(S(N)(=O)=O)n1 +Cc1ccc(C)c(OCCCSc2nncn2C)c1 +C=C(C)Cn1c(CCCNC(=O)C2CC2)nc2ccccc21 +Cc1cc(C(C)C(=O)N2CCCN(Cc3nccn3C)CC2)c(C)o1 +O=C(NC1CCC(O)CC1)NC1(c2ccc(F)cc2)CCC1 +CCNc1ccccc1C(=O)N(CCC#N)C(C)C +O=C1CC2C(CCN2Cc2ccncc2)N1c1cccnc1 +c1ccc2nn(CCn3nnc4ccccc43)nc2c1 +Cc1nnc2sc(SCC(=O)c3ccccc3)nn2c1=O +COC(=O)c1ccc(-n2nc(C(C)C)c3c2CCNC3)cc1 +CC1CN(C(=O)c2cc(=O)[nH]c3ccc(F)cc23)CCO1 +Cc1ccc(OCC(=O)Nc2nnc(-c3ccc(F)cc3F)o2)cc1 +NC(=O)Cn1c(=O)nc(N)c2c3c(sc21)CCCC3 +CN(C)C(=O)CNC(=O)C1CCN(c2ccc(F)c(F)c2)C1=O +COc1ccccc1CN(C)C(=O)c1sc(-c2nc[nH]n2)nc1C +Cc1ccc2cnn(CCC(=O)NCCCO)c2c1 +Cc1nn(Cc2ccc(F)cc2)c2sc(C(N)=O)cc12 +Cc1ccc(S(=O)(=O)NC2CCCC2)cc1C +CCOC(=O)N1CCN(C(=O)c2cc(C)nc3cc(F)ccc23)CC1 +O=C(CCC(=O)NCc1ccco1)NCc1ccccn1 +CS(=O)(=O)N1CC2COCC2(COc2ccc(C#N)cn2)C1 +COC(=O)c1cccc(C(=O)N(C)Cc2ccc(F)c(F)c2)c1 +COc1nn(C)cc1C(=O)N(Cc1cccs1)Cc1cccn1C +CSc1nc(C)c(CCC(=O)OCc2ccccc2F)c(=O)[nH]1 +O=C(Cc1ccccc1O)N1CC(CO)C(CN2CCOCC2)C1 +O=C(NCC1CCCO1)C1CC(=O)N(CC2CC2)C1 +CC(NCc1noc(C2CC2)n1)c1nnnn1-c1ccccc1 +CC(NC(=O)c1ccc(=O)n(C)n1)c1ccc(Br)cc1 +CCCCN(C)C(=O)COc1ccc(C(C)=O)cc1N +CC(C)c1cc(C(=O)NCc2csc(N3CCCC3)n2)no1 +O=C(Cc1ccccc1F)NCCc1ccn(-c2ccccc2)n1 +COC(=O)c1cc2c(=O)n(-c3cccc(OC)c3)ccc2nc1C +CN(C)C(=O)c1nc2ccccn2c1-c1ccc(F)cc1 +COc1cccc(-c2n[nH]c3c2C(c2cccc(O)c2)NC3=O)c1 +Cc1n[nH]c(C2CN(CC(=O)Nc3sc(C)c(C)c3C)CCO2)n1 +CC(C)COc1cc(C(=O)NCc2ccncc2)ccc1N +CC(NC(=O)c1cnc(C2CC2)[nH]c1=O)c1nc2ccccc2[nH]1 +COc1cccc(C(=O)NCCN2CCOCC2)c1OC +N#Cc1nc(NC(=O)c2cc3ccccc3o2)[nH]c1C#N +Cc1cccc(C(=O)OC(C)C(=O)N(C)C)c1N +Cc1nc(C2CCCN(C(=O)c3ccoc3)C2)sc1C +CCCCCNC(=O)COc1cccc2c1CCC2=O +Cn1cc(NC(=O)NCCCC(=O)Nc2ccc(Cl)cc2)cn1 +CCNC(=O)CN(CC)C(=O)c1cnn(-c2ccccn2)c1C +CNC(=O)C(NC(=O)Nc1ccc(OC)cc1)c1ccccc1 +CCC(=O)Nc1ccc(C(C)NC(=O)NCc2ncccc2C)cc1 +Cc1nc2c(ccc3nc(NC(=O)NC4CCCC4)sc32)s1 +CCOC(=O)C1=C(COc2ccc(Cl)c(C)c2)NC(=O)NC1C +N#Cc1cccc(NC(=O)c2ccc(Cl)cc2)c1 +COc1ccc(NC(=O)c2cccc(NC(N)=O)c2)cc1Cl +CC(C)c1noc(-c2ccc(N3CCCC3CO)nc2)n1 +O=C(c1sc(-c2ccco2)nc1-c1ccccc1)N1CCC1 +Cc1ccn2cc(-c3ccc(NC(=O)C4CCOCC4)cc3)nc2c1 +CC(C)NC(=O)CN(C)C(=O)CN(C)c1ncnc2[nH]cnc12 +C=CCNC(=O)CN1CCN(c2nc(C3CC3)ns2)CC1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)N(CC(C)C)CC(C)C)c1 +CCC(=O)Nc1sc2c(c1C(N)=O)CCC(C)C2 +Cn1nnnc1SCc1ccc(C(=O)Nc2nccs2)cc1 +CC(C)(C)OC(=O)N1CCN(c2ccc(F)c(F)c2)CC1 +CNS(=O)(=O)c1ccc(C(=O)Nc2cc(OC)ccc2F)o1 +O=C(c1cnccn1)N(Cc1ccco1)c1ccccc1 +COC(=O)c1cnc(NC(=O)Cc2n[nH]c(=O)c3ccccc23)s1 +Cc1cc(CC2COCC2NC(=O)CN(C)c2ccccc2)on1 +O=C(NCCN1CCCCCC1=O)c1cnc(-c2ccccc2)nc1 +Nc1cc(Cl)ccc1C(=O)NCCc1ccsc1 +NS(=O)(=O)c1ccc(CNC(=O)C2CCCO2)cc1 +CCC(C)NS(=O)(=O)c1ccc(-c2cnc(C)o2)cc1 +Cc1cccc(OCC(=O)N2CCN(CCO)CC2)c1 +CCN(CC)C(=O)c1ccc(C(=O)NCc2cc(C(C)C)no2)cc1 +CCC(O)c1cnc2c(C)cc(Br)cn12 +COC(=O)c1ccc(C)c(NC(=O)CNc2cccc(C#N)c2)c1 +CCCCC(=O)N1CCCC1C(=O)c1ccc(OC)cc1 +CCNC(=O)CNC(c1ccccc1)c1cccc(F)c1 +O=C(COc1ccccc1F)Nc1cccc(OCC2CCCO2)c1 +CC(=O)N1CCCC(Cc2ccc(Nc3ccccc3F)nn2)C1 +CCCNC(=O)Cn1nnc2c(C)nn(CC)c2c1=O +CCCn1c(CCNC(=O)c2ccccc2C)nc2cccnc21 +CCc1cccc(NC(=O)N2CCC(O)(CCOC)C(C)C2)c1 +Cc1c(C(C)NC(=O)CCCn2cncn2)cnn1-c1ccccc1 +NC(=O)CCn1cc(-c2cccc(-c3ccn[nH]3)c2)cn1 +CN(CC(=O)NCCc1ccccc1Cl)c1ncnc2[nH]cnc12 +CCc1nc(NC(=O)Cn2nc(-c3ccco3)ccc2=O)sc1C +COc1cc(S(=O)(=O)NCc2ccccn2)c(OC)cc1Cl +CCN(CC(=O)NC)C(=O)c1cnc(-c2ccccc2)s1 +CC(C)NC(=O)c1cncc(-c2ccc(F)c(F)c2)c1 +Cc1nc(C(NC(=O)C2CCCCC2)c2ccccc2)n[nH]1 +CC(=O)N(Cc1ncc(C)o1)C1CCN(Cc2ccc(C#N)cc2)C1 +COc1cncc(-c2noc(Nc3cccc(Cl)c3)n2)n1 +Cc1nc(OCCNC(=O)c2cccnc2)cc(N2CCOCC2)n1 +CCN1CC(C(=O)N(C)CC(=O)NC(C)(C)C)CC1=O +COC(=O)CCn1c(C(C)C)nc2cc(O)ccc21 +C=CCNc1nc(NCC=C)nc(N2CCOCC2)n1 +O=C(CCn1nc(-c2cccs2)oc1=O)Nc1ccccc1 +CC(=O)N(C)C1CCN(C(=O)Nc2cc(-c3ccccc3)on2)CC1 +O=C(CN(Cc1cccs1)c1ccc(F)cc1)NC1CCOCC1 +O=C(Nc1ccccn1)C1CCCN1S(=O)(=O)c1cccs1 +CCn1nc(C(=O)Nc2sc3c(c2C(N)=O)CCC3)cc1C +CNC(=O)c1ccccc1C#CCNC(=O)NC(C)C +O=C(NCCc1cccc(Cl)c1)NCc1ccncc1 +COC(=O)c1ncccc1OCc1nc(-c2sccc2C)oc1C +Cc1c(C(=O)N2CCC(C(=O)N(C)C)CC2)cnn1-c1ccccn1 +CCCCn1ccc2nc3ncnn3c(-c3ccc(F)cc3)c2c1=O +CC1Oc2ccccc2OC1C(=O)N1CCCC(N2CCNC2=O)C1 +CN(Cc1cccc(Cl)c1Cl)C(C(N)=O)c1ccc(F)cc1 +CCCOc1cc(OC)cc2c1CCNC2c1ncccn1 +Cc1cc(=O)cc(C(=O)N2CCC3(CCC(=O)N(CCO)C3)CC2)o1 +Cc1ccc(C(=O)NCC(F)(F)F)cc1NC(=O)N(C)CCC#N +CCCOc1ccc2c(c1)CCN(C(=O)Nc1cnccc1C)C2 +Cc1cccc(NC(=O)C(C)N2CC(C)Oc3ccc(N)cc32)c1C +Cc1ccc(NC(=O)CSc2nncn2C)c(C)c1 +CCNC(=O)Nc1ccccc1Cc1nc(-c2cccnc2)no1 +CCC(C(=O)OCC(=O)Nc1cc(C)on1)c1ccccc1 +CC(NC(=O)Nc1cccc(C#N)c1)c1ccncc1 +O=C(Nc1ccc(Cl)cc1)c1cc2c([nH]c1=O)CCCC2 +Cc1cc(F)cc(Br)c1CN1CCOCC1 +Cc1nnc(NC(=O)C2CC(=O)N(C(C)(C)C)C2)s1 +Cc1cc(C)cc(OCC(=O)NCc2ccncc2)c1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)CO3)cc1F +COc1cccc(Cn2ccnc2-c2nc3ccccc3n2C)c1OC +Cc1cccc(NC(=O)Nc2ccccc2Cl)n1 +Cc1cccc(NC(=O)CSc2nc(C)c(CCO)c(=O)[nH]2)c1 +CC(=O)NCCNC(=O)N(C)Cc1cc(Br)cs1 +CN(CCC#N)C(=O)Cn1nc(C#N)cc1-c1ccncc1 +O=C(c1ccncc1)N1CCC2(CCN(c3cccnc3)C2=O)C1 +O=C(CCNC(=O)c1ccccc1)Nc1nnc(C(F)(F)F)s1 +NC(=O)COC(=O)C1(c2ccccc2)CCOCC1 +CCn1cc(Br)c(C(=O)NCCCN2CCOCC2)n1 +CCNC(=O)N1CCN(C(=O)c2ccccc2OCC)CC1 +CC(NCC(C)(O)c1ccc(S(C)(=O)=O)cc1)c1ccccc1 +O=c1cc(-c2cccc(Br)c2)[nH]c(=O)[nH]1 +CCCNC(=O)c1nnn(-c2ccccc2Cl)c1-c1ccncc1 +Nc1ccc(F)c2c(Br)cnc(N3CCOCC3)c12 +Cc1ccc(CC(=O)N2CCN(Cc3nnc(C4CC4)o3)CC2)cc1 +Cc1cnn(-c2ccc(C(=O)NCC3CC3)cc2)c1 +CNC(=O)COc1ccc(CNC(=O)NC(C)C)cc1 +C#CCOc1ccc(NC(=O)c2cc(=O)n(-c3ccc(C)cc3)[nH]2)cc1 +CCN(CC)C(=O)c1ccccc1NC(=O)COC1CCCCC1 +CCC(CC)NC(=O)N1CCN(C(=O)c2ccccc2)CC1 +COc1cc(C)c(S(=O)(=O)N(C)CC(=O)N(C)C)cc1C +OCC1(COc2ccc(-c3nnco3)cc2)COC1 +CN(CC1CCCN1c1ccc2nccn2n1)C(=O)OC(C)(C)C +CN(Cc1cnn(C)c1)C(=O)c1cccc(NS(C)(=O)=O)c1 +O=C(NCCNC(=O)N1CCN(c2ccccc2F)CC1)C1CC1 +CC(CNC(=O)N(C)Cc1ccncc1)Cc1cccs1 +OCc1cccnc1NCc1ccc(F)c(F)c1 +COCCn1c(-c2ccccc2)nc2c1CCCC2=O +Cc1cc(C)cc(-n2ncc3c(N4CCOCC4)ncnc32)c1 +CCOc1ccc(CC(=O)Nc2cc(N3CCCCC3)ncn2)cc1 +CCn1cnnc1CNC(=O)NCc1c(C)cc(C)[nH]c1=O +O=C(Nc1ccc(F)cc1)c1cnc2n(c1=O)CCS2 +CNc1snc(C)c1C(=O)Nc1cccc(C(=O)NC2CC2)c1 +Cc1ccc(NC(=O)COc2cccc3ccc(=O)[nH]c23)c(C)c1 +Cc1cccc(-n2ccnc2SC(C(N)=O)c2ccc(F)cc2)c1 +Cc1ccc(C)c(-n2c(C)nnc2SCC(=O)NC(C)C)c1 +Cc1noc(C)c1C(C)c1nc(-c2ccc(C#N)cn2)no1 +O=C(NCC1Cc2ccccc2O1)Nc1ccc2c(c1)COC2 +CCCC(=O)Nc1cccc(NCc2noc(C(C)C)n2)c1 +COc1ccc(S(=O)(=O)NCc2ccccc2Cl)cc1OC +CC(C)C1C(=O)NCCN1C(=O)C1CCOc2ccccc21 +COc1cc(CO)cc(Cl)c1OCc1cnc(C)s1 +Cc1nn(CC(=O)NCCCn2cccn2)c(C)c1Br +O=C(Nc1cc(C2CCCC2)[nH]n1)c1ccc(Cn2ccnc2)cc1 +O=C(CCc1nc(-c2ccccn2)no1)NCc1cscn1 +O=C(Cn1cccn1)N1CCCC(COc2ccc(F)cc2)C1 +COc1ccc(Cl)cc1CCN(C)C(=O)CCC#N +CCOC(C)(OCC)C(O)(c1ccccc1)c1ccccc1 +CCCCn1c(N)c(N(CC(C)C)C(=O)CC)c(=O)[nH]c1=O +CC(=O)c1ccc(NC(=O)Cn2nnc3ccccc3c2=O)cc1C +Cc1c(C(=O)NCCCn2ccnc2)[nH]c2c1C(=O)CC(C)(C)C2 +Cc1ccc(CCNC(=O)C2CCC(=O)N2Cc2cccnc2)cc1 +Cc1nc(C)n(CCCNc2nc(C(C)(C)C)nc3c2cnn3C)n1 +O=C(Cc1cccc(F)c1)NCC(=O)Oc1ccc(Cl)cc1 +COc1ccc(NC(=O)c2cnccn2)c(OC)c1 +Cc1nnc(CNC(=O)COc2ccc(Cl)cc2Cl)o1 +CCCC(=O)N1CCC(OCc2ccccc2F)CC1 +O=C(Nc1cccnc1-n1cc(Cl)cn1)C1CCCCC1 +COc1ccc(C)cc1NC(=O)Cn1nc2c(cc1=O)CCCC2 +CCCn1cc(-c2ccncc2)cc1C(=O)NCCOC +CNC(=O)CSc1nnc(COc2cccc(C)c2)n1C +O=C(CC1CCCO1)Nc1ccc(Cl)cc1NC(=O)c1ccco1 +N#Cc1cnc(Nc2ccc3c(c2)OCO3)nc1N +Cc1ccc(S(=O)(=O)CC(=O)N2CCCCC2C)cc1C +Cc1ccc(-n2nnc(C(=O)Nc3ccc4c(c3)OCO4)n2)cc1 +CCC1COCCN1C(=O)c1ccc(NC)c(C)c1 +CCOC(=O)N1CCC(NC(=O)Nc2ccc(F)c(C)c2)CC1 +CC(=O)NC(CC(=O)N1CCOC(C)C1)c1ccc(C)cc1 +O=C(NCCc1cccs1)c1ccnc2ncccc12 +Cc1cc(C(=O)N2CCN(c3ncccn3)CC2)n(-c2ccccc2)n1 +COCCN1CCN(Cc2ncc(C)o2)CC1=O +CCn1c(=O)oc2cc(NS(=O)(=O)c3ccc(F)cc3)ccc21 +CCCNC(=O)CN(C)C(=O)NCCNC(C)=O +CCCC(=O)N1CC(c2nc(-c3ccccn3)no2)C1 +CCN(C(=O)c1cnc(Cc2ccccc2)s1)c1cccnc1 +COC(=O)c1c(NC(=O)c2ccc(Cl)cc2Cl)c(C)nn1C +CC(C)c1cc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)nn1C +Cc1cc(C)c2c(N3CC(C)OC(C)C3)ncnc2n1 +CC(=O)N1CCC(C(=O)OCCCc2ccncc2)CC1 +Cc1cn2c(CC(=O)Nc3cccc(S(C)(=O)=O)c3)csc2n1 +CCNC(=O)COc1ccc(C2NC(=O)c3cccc(C)c3N2)cc1 +C#CCC(N)c1nc(-c2ccc3ccccc3c2)cs1 +O=C(Nc1n[nH]c(Cc2cccc(F)c2)n1)c1ccncc1Cl +O=C(Cc1ccon1)Nc1cc(Cl)cc(Br)c1O +COc1ccc(C(C#N)CC(=O)Nc2ccccc2)c(OC)c1 +CNC(=O)COC(=O)c1cnn(-c2ccccc2C)c1C +COc1cc(C)c(C(=O)NC(C#N)c2cccc(Cl)c2)cc1OC +COC(CCc1ccccc1Br)(OC)OC +CN(C(=O)Nc1cccn(Cc2ccccc2)c1=O)C1CCC1 +COc1ccccc1C(NC(=O)c1ccc(C)[nH]c1=O)C(C)(C)C +Cc1ccc(SCCC(=O)Nc2ccccc2N)cc1 +CCOC(=O)C(O)c1nnc2c(N(C)C)cc(C)nn12 +Cc1nnc(SCC(=O)c2ccc(Cl)cc2)n(N)c1=O +Cc1ncsc1CCN1CCN(C(=O)Cc2c(C)noc2C)CC1 +CCC1CCCCN1C(=O)Cc1csc(-c2ncccn2)n1 +Cc1nc(-c2c[nH]c(C)cc2=O)n(Cc2ccccc2C)n1 +CCc1ccc(CC2Oc3cc(O)ccc3N(C)C2=O)cc1 +O=C(c1cccc(-n2cnnn2)c1)N1CCOc2ccc(F)cc21 +COc1cccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)(C)CO3)c1 +Cn1c(C(=O)Nc2nccs2)cc2ccc(F)cc21 +COC(=O)c1cccc(CCNC(=O)c2c[nH]nc2-c2ccccc2)c1 +CCC(CCNC(=O)c1ccc(N(C)C)cc1)N1CCCC1=O +CCOC(=O)NCCC(=O)Nc1nnc(-c2ccc(C)cc2C)s1 +O=C(CCNC(=O)C1CC(=O)N(c2ccccc2)C1)NC1CC1 +CC1CCCCN1S(=O)(=O)c1ccc(-n2cnnn2)cc1 +COC(=O)c1sccc1S(=O)(=O)Nc1cc(C)ccc1C +CCCN(C)C(C(=O)NCc1ccc2c(c1)OCO2)c1ccccc1 +CCN1CCC2(CCN(S(=O)(=O)CC)CC2)C1=O +COc1cc(Cl)c(OC)c2c1CCNC2C(C)C +Cc1ccc(NC(=O)c2c(C)c(N)c(C)[nH]c2=O)cc1C +N#CCn1cnc2c(nnn2-c2ccccc2)c1=O +O=C(Nc1ccnc2ccc(F)cc12)c1ccccc1F +CCc1cc(CNC(=O)c2cc(C)nc3c(C)cccc23)on1 +CC(c1cccnc1)N(C)S(=O)(=O)N(C)CCC#N +Cc1nccc(C2CN(S(=O)(=O)c3cn(C)cn3)CCO2)n1 +COCC(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1C +CN1C(=O)CC(C(=O)N2CCC(O)CC2)C1c1cccc(Cl)c1 +COc1ccc(CC(=O)NCc2cnc(C)s2)cc1OC +CCS(=O)(=O)NCCn1nc(-c2ccccn2)n(C)c1=O +CC(C)CCC(=O)N1CCN(C(=O)Nc2cccnc2)CC1 +CN(C)C(=O)NCc1nnc2n1CCN(Cc1cccnc1)C2 +CCOC(=O)C1=C(C)C(S(=O)(=O)NCc2cccnc2)C(C)=N1 +CNC(=O)C1CC2CN(C(=O)Cc3ccc(F)cc3)CC2N1C(C)=O +Cc1c(C(=O)NCc2ccccc2)nc2ccc(Cl)cn12 +NC(=O)Cc1csc(NC(=O)c2cccc(-n3cccc3)c2)n1 +COC(=O)C(NC(=O)C(C)Oc1cccc(Cl)c1)C(C)C +COC(=O)c1ccc(Cn2cc(NC(=O)C(C)(C)C)cn2)cc1F +O=C(NCC1COc2ccccc2O1)Nc1nccs1 +Cc1noc(-c2cccs2)c1C(=O)NC1CCc2ccccc21 +CCOc1ccc2[nH]c(=O)c(CNc3cccc(OC)c3)cc2c1 +CC(=O)N1CCC(CCC(=O)Nc2nc3ccc(F)cn3n2)CC1 +CN(Cc1ccc2ccccc2n1)C(=O)CC1CCc2ccccc21 +CCc1cc(C(=O)NCCN(CC)c2ccccc2C)[nH]n1 +COC(=O)c1cccc(C(=O)Nc2cccnc2N2CCCC2)c1 +CC(=O)N1CCc2cc(NC(=O)Cc3cccc(OCC#N)c3)ccc21 +CC(Sc1nnc2n1CCCCC2)C(=O)N1CCCCCC1 +O=C(NCCNc1cccnc1)c1cccc(-c2ccc(O)cc2)c1 +Nc1c(C(=O)Nc2ccccc2)nnn1Cc1ccc(F)cc1Cl +CC(C)(C)OC(=O)NCC1(NC(=O)c2ccoc2)CCCC1 +CNS(=O)(=O)Cc1ccc(CNC(=O)C2CCCCC2)cc1 +CCCC1CCC(NS(=O)(=O)N2CCOCC2)CC1 +Cc1ccnn1CC(=O)Nc1cnn(COCC(F)(F)F)c1 +COC(=O)c1ccc(C(=O)NCCC(C)(C)C)cc1 +Cc1cc2nc(COC(=O)COc3ccccc3)cc(=O)n2o1 +N#Cc1c(N)nc2c(c1-c1ccc(O)cc1)Cc1c(O)cccc1-2 +CN(CCc1ccccn1)S(=O)(=O)c1ccc(Cl)c(Cl)c1 +CC(NC(=O)CCNC(=O)c1ccccc1)c1ccc(F)cc1F +CN(Cc1nccn1C(F)F)C(=O)CCCc1c[nH]c2ccccc12 +Cc1ccc(C)c(NS(=O)(=O)c2ccc(-c3nnc(C)o3)o2)c1 +Cc1cc(C)cc(OCCN(C)C(=O)c2ccco2)c1 +CC(=O)N1CCN(C(=O)c2csc(C)n2)CC1 +CCCC1CN(C(=O)c2nn(-c3cccc(Cl)c3)nc2C)CCO1 +CCCCN(CC)C(=O)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +CCOc1ncccc1NC(=O)N1CCN(S(C)(=O)=O)CC1 +COc1cccc(OC)c1-c1noc(-c2cccc(C)n2)n1 +CC(=O)c1sc(N(C)Cc2ccc(C)o2)nc1C +Cc1cc(S(=O)(=O)N(C)C)ccc1OCC(N)=O +O=C1CCc2ccc(C(=O)NCCc3ccccc3)nc2N1 +Cc1nnc(NC(=O)NCc2ccccc2Cl)s1 +COc1ccccc1OCC(=O)c1ccc(Cl)cc1 +O=C(Oc1coc(CSc2ncccn2)cc1=O)c1cccs1 +O=C(Nc1cccc(F)c1)Nc1cc(N2CCCCC2)ncn1 +Cc1ccc(-n2nnc(C(=O)N3CCNC(=O)C3)c2C)cc1 +COCCNC(=O)c1cc2c(=O)n(Cc3ccccc3)ccc2s1 +CCN(CC(C)C#N)C(=O)CNc1ccc(F)c(NC(C)=O)c1 +Cc1occc1C(=O)N(C)C(C)c1ccc(S(N)(=O)=O)cc1 +CNC(=O)CCc1ccc(-c2ccc(OC)cc2)o1 +O=C(NCC1Cc2ccccc21)c1ccccc1Br +CC(C)c1n[nH]c(C(=O)Nc2cc[nH]n2)c1Br +Cc1ccc(NCC(=O)NCC2COc3ccccc3O2)cc1F +Cc1ccccc1CC(=O)Nc1ccc(C(N)=O)c(Cl)c1 +Cc1cc(OCC(=O)N2CCC(C)CC2)nnc1C +CNC(=O)c1ccccc1NCc1ccc(C#N)cc1 +O=C(NCc1cc(-c2cc3ccccc3o2)on1)c1ccncc1 +CCC(C)C(C)NC(=O)NCCCc1c(C)noc1C +CCn1cc(C(=O)NCc2ccc(O)c(OC)c2)c(C)n1 +Cc1ccc2c(CN3CCCC4(C3)OCCO4)cc(=O)oc2c1 +Cn1nccc1CNC(=O)NCCc1nccn1Cc1ccccc1 +C#Cc1cccc(NS(=O)(=O)c2cc(C)ccc2O)c1 +Cc1cnn(-c2ccc(C(N)=O)cc2NC(=O)C2CC2(C)C)c1 +O=S(=O)(c1ccc2c(c1)CCC2)N1CCC(CO)CC1 +COc1ccc(N2CC(c3nc4ccc(C)cc4[nH]3)CC2=O)cc1 +CC(=O)c1cc(C(=O)NC(C)CC(=O)c2cccs2)n(C)c1 +Cc1nc(C)c(CCC(=O)NC(C)c2cc(C)oc2C)c(=O)[nH]1 +Cn1c2ccc(N)cc2n2c(COc3ccccc3)nnc12 +Cn1cc(S(=O)(=O)Nc2ccccc2Cl)c(N)n1 +CCCn1ncc(C(=O)NC2CC2c2ccccc2)c1C +CC1CCCC(C)N(C(=O)CCc2nc(-c3ncccn3)no2)C1 +Cc1ccc(CN(C)C(=O)COc2ccc(F)cc2Cl)o1 +COC(=O)c1ccc2[nH]c(C)c(CN3CCOCC3)c(=O)c2c1 +COc1cccc(C(=O)N2CCN(C)c3ccc(F)cc32)c1F +COc1ccc(C)c2c1N(C(=O)c1cnc3onc(C)c3c1)CCC2 +CNc1nc(-c2ccc(C)n(C3CCCCC3)c2=O)cs1 +Cc1cnc(C(=O)N2CC3COCC3(CN3CCOCC3)C2)cn1 +NC(=O)C1CCN(Cc2ncc(C(F)(F)F)cc2Cl)CC1 +Cc1ccc(CNC(=O)c2cc(-c3csc(C)n3)c[nH]2)s1 +CCC(=O)Nc1ccc(NC(=O)c2nc3nc(C)cc(C)n3n2)cc1 +CN(C(=O)c1cn(CCC2CCCCC2)nn1)C1CCOCC1 +CC(=O)c1ccccc1OCC(=O)Nc1ccc2c(c1)OCO2 +COc1cccc(C(=O)NCc2ncc(C)c(OC)c2C)c1F +CC(NC(=O)Nc1ccccc1F)C(=O)NC(C)(C)C +N#Cc1cc(F)c(N2CCN(C(=O)c3ccsc3)CC2)c(F)c1 +NC(=O)c1ccc(COc2ccc(Cl)cc2N)cc1 +CC(=O)N1CCN(C(=O)c2nc(C)cc3c(N)cccc23)CC1 +N#CCCCN1CCN(c2ccc(Br)cn2)CC1 +CCc1nc(NCCCO)c2c(n1)c(C)nn2CC +Cc1ccc(CN(C)C(=O)CCc2ccccc2)o1 +CCCC1NC(=O)C2CC(NC(=O)c3ccccc3Cl)CN2C1=O +CCOC(=O)c1cc(C#N)c(SCC(=O)N2CCOCC2)nc1C +Cc1cccc(OCCN(C)C(=O)CCC(=O)N2CCOCC2)c1 +CN(CC1CC1)C(=O)CSc1nnc(-c2ccc(F)cc2)o1 +C=CCN(C(=O)c1cc(Br)cn1CC)C(C)C +COc1ccc(NC(=O)c2cc(-c3cccnc3)on2)cc1Cl +Cc1nc(C)c(C2NCCc3cccc(Cl)c32)s1 +Cc1cc(C(=O)N2CC(C(=O)N(C)Cc3ccccc3)C2)no1 +CC(=O)N1CCC(C(=O)Oc2cccc(Br)c2)CC1 +Cc1nn2cccnc2c1C(=O)OCCCc1ccncc1 +CCOc1cccc(CNC(=O)c2ccc(OC)c(F)c2)c1 +CCNC(=O)COc1ccc(Br)cc1F +CNC(=O)CSc1nnnn1-c1cccc(C)c1 +Cc1nc(CN2CCN(CC(=O)N(C)Cc3ccco3)CC2)cs1 +COC(=O)c1sc(NC(=O)c2ccc(C)s2)nc1C +Cc1cccc(-c2nnc(NC(=O)c3ccnn3C)o2)c1 +Cc1ccc(Cn2c(=O)[nH]c3ccsc3c2=O)cc1C +CCOC(=O)c1cn(CC(=O)OC)c2ccc(F)cc2c1=O +COc1cccc(CNC(=O)c2cccc(-n3cnnn3)c2)c1 +Brc1cnc2c(c1)OCCn1ccnc1-2 +N#Cc1cccc(C(=O)Nc2nnc(Cc3ccccc3)o2)c1 +Cc1cc(C)cc(NC(=O)c2cnc(C)c(N)c2C)c1 +Nc1ccc(-n2nnnc2C2CC2)cc1C(F)(F)F +O=C(Nc1cccc(N2CCOC2=O)c1)C1CC2CCC1C2 +Cc1csc(-n2nnc(C#N)c2-c2ccco2)n1 +CS(=O)(=O)N1CCC(C(=O)OCc2ccccc2)CC1 +CCCC(=O)Nc1ccc(OC)c(S(=O)(=O)N2CCOCC2)c1 +CC(OC(=O)CCNC1=NS(=O)(=O)c2ccccc21)C(N)=O +CC(=O)NCCCN(C)C(=O)C1COc2ccccc2O1 +CCc1noc(CC)c1CNC(=O)NCCc1c(F)cccc1F +CC1CCCC(N(C)C(=O)C(C)NC(=O)C(C)(C)C)C1 +O=C(c1cccc2ncccc12)N1CCCC(c2ccn[nH]2)C1 +Cc1cccc(NC(=O)CCC(=O)Nc2nnc(CC(C)C)s2)c1 +C=CCOC(=O)CCn1cnc2c(C)cccc2c1=O +O=C(c1cc(Cl)ccc1F)N1CCC2(CC1)OCCO2 +COc1ccnc(NC(=O)c2cc(C)c(C)s2)c1 +O=C(Nc1ccnn1C1CCCCC1)c1ccc[nH]c1=O +Cc1cc(C(=O)OCCCC(N)=O)c(C)cc1Br +O=C(Cc1ccccc1)NCCc1nnc2ccccn12 +O=C(NCCC1=CCCC1)N1CCOCC1C1CC1 +CCOc1cc(C(=O)NCCc2c[nH]c3ccccc23)ccc1OC +CN(C)C(=O)N1CCc2ncnc(C3CCOC3)c2CC1 +O=C(CC1(O)CCCCC1)NCCNC(=O)C1CC1 +CC(C(=O)Nc1ccc2oc(C3CC3)nc2c1)c1cccs1 +Cc1csc(CCCNC(=O)N2CCOC3(CCCC3)C2)n1 +CC(=O)Nc1ccc2c(c1)S(=O)(=O)c1cc(NC(C)=O)ccc1-2 +CCCCNC(=O)C(N)c1ccc(OC)c(C)c1 +CCC(=O)NC1CCCN(C(=O)Cc2ccc(-n3cccc3)cc2)C1 +O=C1N(Cc2cccnc2)CC2CN(C3CCOCC3)CCN12 +Cc1nc(CNc2ccc(S(=O)(=O)N(C)C3CC3)cc2)cs1 +CCOCCNC(=O)NCC1(c2ccc(F)cc2)CC1 +O=C1CCc2cc(OC(=O)Cc3coc(-c4ccccc4)n3)ccc2N1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)N1CCc2ccccc2C1 +CCCc1cc(=O)n(CC(=O)NCCn2ncccc2=O)cn1 +Cc1ccc(C)c(C(=O)Nc2cnc(-n3ccnc3)nc2)c1 +COC(=O)N(C)c1ccc(NC(=O)CC(C)(C)C)cc1 +CN(CC(O)c1ccc(F)cc1)C(=O)Nc1cnc(C(C)(C)C)nc1 +Cc1nn(C)c2ncc(C(=O)NCC3CCC3)cc12 +NC(=O)CCOc1ccccc1NC(=O)CC1C=CCC1 +Cc1cc(-c2cnc(NCc3ccco3)nc2-c2ccco2)on1 +COCc1nc2n(n1)CCCC2Nc1nc(C2CC2)no1 +CCCCCn1c(SCc2nnc(C)o2)nc2ccccc21 +Cc1cc(C)c(NC(=O)c2nccn2C2CC2)c(C)c1 +CC(C)C1COC(=O)N1Cc1c(F)cccc1Cl +O=C(Cc1ccccc1)N1CCCC(c2nc3ccccc3[nH]2)C1 +CCC(Oc1ccc(OC)cc1)C(=O)Nc1ccccc1C(N)=O +Cc1cc(=O)oc(C)c1C(=O)OC(C(N)=O)c1ccc(F)cc1 +COc1ccccc1CNC(=O)CCS(=O)(=O)N1CCNCC1 +Cc1cccc(NC(=O)N2CCN(CC(=O)N3CCCC3)CC2)c1 +Cc1cc(CNC(=O)c2cccc3c2OC(C)C(=O)N3)c(C)o1 +CCS(=O)(=O)NCC1(c2ccc(F)cc2F)CC1 +Cc1ccc(-c2n[nH]c(NC(=O)c3ccc(-n4cncn4)cc3)n2)cc1 +CCCNC(=O)c1ccc(N(CC)S(C)(=O)=O)cc1 +Cc1ccc(CN(C(=O)c2ccnc(-n3ccnc3)c2)C2CC2)o1 +O=C(NC1CCCCCC1)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +Cc1cccc(OCCNC(=O)c2ccc3c(c2)NC(=O)CS3)c1 +C=CCN(CC=C)S(=O)(=O)c1ccc2c(c1)CCCN2 +CC(NC(=O)c1ccc(F)cc1F)c1cccc(S(N)(=O)=O)c1 +CCN(CC)C(=O)C1CC(NC(=O)c2ccn(C(C)(C)C)c2)CN1C +Cc1cccc(Oc2ccc(C(=O)N3CCC(CO)C(O)C3)cc2)c1 +CCc1cc(N(C)Cc2cnn(CC)c2)n2nccc2n1 +CCCC(=O)c1ccc2c(c1)N(C(CC)C(=O)OC)C(=O)C(C)O2 +CCn1cnnc1CNC(=O)NCC1Cc2ccccc2O1 +O=C(NC1CCCCC1)c1n[nH]c(=O)c2ccccc12 +CCNC(=O)CNC(=O)c1cc2sccc2n1C1CCCC1 +COc1ccc(CCNC(=O)Cc2coc3cc(OC)ccc23)cc1 +CCOC(=O)CN(C)S(=O)(=O)c1ccccc1 +COc1cc(C#N)ccc1OC(C)c1nc(C(C)C)no1 +Cc1nc(NC(=O)C2COc3ccccc3O2)sc1C +Cc1cccc(OCC(=O)N2CC(OCc3ccc(F)cc3)C2)c1 +C=CCOc1ccccc1NC(=O)c1cc(-c2ccccn2)n[nH]1 +CCC(OC1CCCC1)C(=O)N1CCN(C(C)COC)CC1 +CCOC(=O)Cc1csc(NC(C)=O)c1C#N +COC(=O)c1ccc(NC(=O)CCn2ncc3c(C)cccc32)cc1 +c1ccc(N2CCN(Cc3ccc(-n4cccn4)cc3)CC2)cc1 +CCSc1nc2n(n1)C(c1ccc(C)o1)C(C(=O)OC)=C(C)N2 +CCN(C(C)C)S(=O)(=O)c1ccccc1Br +CC(Oc1ccccc1)C(=O)Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3 +CCN(Cc1ccccc1C)C(=O)c1cc(S(C)(=O)=O)ccc1C +CCC(C)n1ncc(C(=O)N=c2[nH]cc(C)[nH]2)c1C1CC1 +O=C(CCc1nc2ccccc2s1)N1CCC2(CCCO2)CC1 +Cc1ccc(C(=O)N(C)C)cc1OCc1cccc(F)c1F +COc1cccc(C(=O)N2CCN(c3ncccn3)CC2)c1F +CNC(=O)CCCC(O)c1cc(C)ccc1OC +CN(Cc1ccco1)C1CN(CC2CCOCC2)C2CCCOC12 +COCCN1C(=O)CCC12CCC(NC(=O)c1cscn1)CC2 +CN(C)c1ccccc1NC(=O)CNS(=O)(=O)c1cnn(C)c1 +Cc1c(NS(=O)(=O)c2cccs2)cccc1-n1cnnn1 +O=C(NCc1cc[nH]n1)NCC(c1cccs1)N1CCOCC1 +C=CCCOC(C)C(=O)N1CCC(c2nncn2CC)CC1 +COc1ccc(S(=O)(=O)NCc2c[nH]nc2C)cc1F +O=C(NCC1NCCc2ccc(F)cc21)c1ccccc1 +CCCNC(=O)C1(NC(=O)c2ccc(C#N)cc2)CCCCC1 +CN(C)C(=O)COc1ccc(Nc2ccccc2)cc1 +Cn1cccc1C(=O)N1CCCC1c1ccccc1Cl +O=C(Nc1cccn2nc(C3CCC3)nc12)C1CCCO1 +O=C(NCc1ccc(Cl)cc1)C1CCN(c2ncccn2)CC1 +O=C(c1ccnc(OC2CCCCC2)c1)N1CCCC1CO +CS(=O)(=O)c1ccc(-c2cc(C#N)c(C3CC3)o2)cc1 +Cc1cc(C)c(NC(=O)CN(C)c2cc(C)nc3ncnn23)c(C)c1 +Cc1ccc(N)c2nnc(CCOc3ccccc3)n12 +CCc1ccc(NCCc2n[nH]c(C3CC3)n2)cc1 +CNc1ncc(S(=O)(=O)N2CCC(OC)CC2)cn1 +CN(CCC#N)S(=O)(=O)NCc1cn(-c2ccccc2)nn1 +O=C(COC1CCOC1)N1CCCc2cc(Cl)ccc21 +COc1ccc(NC(=O)c2cn(C)nc2OC)cc1OC +N#CCCN(Cc1ccccc1)C(=O)c1ccc(Cl)cc1 +COCC(C)(O)CNC(=O)c1ccccc1Br +Cc1ccc(NC(=O)CNC(=O)c2cc3sccc3n2C)cc1 +C#Cc1cccc(NC(=O)c2cc3ccccc3c(=O)[nH]2)c1 +Cc1cccc(C(N)=O)c1NCc1ccccc1C#N +CCN(C(C)=O)c1nc(C2NC(=O)c3c(C)cccc3N2)cs1 +Cn1cc(CCC(=O)Nc2ccc(OC3CCCCC3O)cc2)cn1 +CCOC(=O)c1cnn(-c2cccc(Cl)c2)c1 +COc1ccc(-n2c(C)nn(CC#N)c2=O)cc1OC +Cc1ccc(NC(=O)N(Cc2cccn2C)C2CC2)cc1C +CC1CCCC(C)N1C(=O)CN(c1ccc(C#N)cc1)S(C)(=O)=O +CN(C(=O)C1CC=CC1)c1ccccc1S(C)(=O)=O +CCCn1nc(C2CCOC2)nc1-c1ccc2c(c1)CCO2 +CNC(=O)c1ccc(CNc2cc(C)c(Cl)cc2OC)cc1 +Cc1nc(-c2cccc(NC(=O)CSc3ccncc3)c2)cs1 +CCOC(=O)C=C(Nc1cccnc1)C(F)(F)F +COc1cccc(NC(=O)c2n[nH]cc2Br)c1 +Cc1cc(C)n2ncc(C(=O)Nc3ccc4c(c3)OC(C)(C)O4)c2n1 +CC(C)OC(=O)c1cc(-c2cc(C(F)(F)F)ccc2O)n[nH]1 +COc1cc(OC)c(C(=O)CC(C)C)c(OC)c1 +Cc1cccc(C(=O)Nc2ccc(N)cc2Br)n1 +C=Cc1c(S(C)(=O)=O)sc(C(=O)NC)c1C +COc1ccc(N)cc1NC(=O)c1ccc(C)cc1C +CN(C(=O)CCNC(=O)C(C)(C)C)C1CCc2ccccc2C1 +Cc1ccn(C(C)CC(=O)NCc2ccccc2)n1 +COCc1ccccc1NC(=O)NCCCC(C)C +COc1ccccc1S(=O)C(C)c1ncc(C(C)(C)C)o1 +COc1ccc(-c2nc(COC(=O)c3cccnc3)cs2)cc1 +O=C(CCn1ccnc1)NCCc1csc2ccccc12 +N#Cc1cc(Cl)ccc1NCc1ccc(=O)[nH]c1 +N#Cc1ccc(NC(=O)c2cccc3c2OCO3)cc1 +COCc1ccccc1C(=O)N1CCC(Nc2cccnn2)CC1 +O=C(Cc1csc(NC(=O)c2ccco2)n1)Oc1ccccc1 +CSc1cccc(NC(=O)NCCC(F)(F)F)c1 +CC(C)CCNC(=O)c1cccc(S(=O)(=O)NC2CC2)c1 +Cc1nc(CC(=O)N2CCn3c(nnc3C(C)C)C2)cs1 +CCOC(=O)N1CCN(C(=O)c2ccc(OC(=O)CC)cc2)CC1 +CC(CC#N)N(C)C(=O)Nc1cccc(C(=O)NC(C)(C)C)c1 +CCCCCNC(=O)CC1CSc2nc3c(c(=O)n21)CCCC3 +CC(C)C(=O)N1CCN(c2ccccc2NC(=O)C(C)(C)C)CC1 +COC(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +CCn1ncnc1C(C)NC(=O)c1cnc(-c2cccnc2)nc1 +Cc1ccc(S(=O)(=O)NCC(=O)C(C)(C)C)c(C)c1 +CN(C)c1nc2sc(C(=O)N3CCNC(=O)C3)cc2s1 +CC(C)C(=O)NCC1CCCN(C(=O)CCCc2ccccc2)C1 +CCCc1nnc(NC(=O)CNC(=O)C(C)(C)C)s1 +CC(C)CC(C(=O)Nc1cc(F)c(F)c(F)c1)N1CCCCC1=O +COc1cc(C2NC(=O)c3c(sc(C)c3C)N2)cc(OC)c1O +Cc1nn(C)c(C)c1CC(=O)NCc1cnn(-c2ccccc2)c1 +CCOc1cccc(NC(=O)c2cn(C)nc2C(C)(C)C)n1 +Cc1cc2sc(NC(=O)N3CCC(C(C)O)C3)nc2s1 +CN(C)C(=O)N1CC2CN(C(=O)c3cnccn3)CC2C1 +CC1CC(C)CN(S(=O)(=O)c2cc3c4c(c2)CC(=O)N4CCC3)C1 +CN(CC1CCCCO1)C(=O)Cn1ccc2ccccc2c1=O +CC(C)c1noc(CCCC(=O)N2CCCC(c3nncn3C)C2)n1 +CCCNC(=O)C1CCCN(C(=O)Cn2nnc3ccccc32)C1 +O=C(Cc1ccnnc1)Cc1cccc(F)c1Br +CC(C)(C)OC(=O)NCCC(=O)NC1C2CCOC2C1(C)C +O=S(=O)(c1cccs1)N1CCN(CCc2ccccn2)CC1 +CC(NC(=O)C1Cc2cc(Cl)ccc2O1)C(=O)N1CCOCC1 +Nc1cc(F)cc2c(N3CCCCCC3)nccc12 +c1ccc(CN2CNC(=Nc3nc4ccccc4o3)NC2)cc1 +COc1ccc(C(=O)CC2(O)C(=O)Nc3ccccc32)cc1OC +CCN1CC(NC(=O)c2coc(COc3cccc(F)c3)n2)CC1=O +O=C(CNC(=O)c1ccc(Cl)cc1)NCCOc1ccccc1 +CCOC(=O)CN(C)S(=O)(=O)c1ccc(F)cc1F +COC(=O)c1nnn(-c2cccc(C(F)(F)F)c2)c1N +Cc1nnnn1-c1nc(-c2ccco2)cc(C(F)(F)F)n1 +Cc1noc(C)c1C1CCCN1C(=O)CN1CCCCCC1=O +COc1ccc(NC(=O)CSc2nc(C)cs2)c(C)c1 +O=C(c1ccccn1)N1CCC2C(COC2CNc2ncccn2)C1 +COc1ccccc1CNC1(Cc2cc(C(C)(C)O)on2)COC1 +COc1ccc(OC)c(C(O)CSc2ccc(C)cn2)c1 +O=C(Nc1cccnc1N1CCCCC1)c1cc2ccccc2c(=O)[nH]1 +CCOC(=O)Nc1c(-c2ccc(Cl)cc2)nc2ncccn12 +CC1(C)CCCN(C(=O)NCCCOC2CCOCC2)CC1 +Cn1nccc1CN(CC(O)c1ccc(F)cc1)C1CC1 +CCOCc1ccccc1CNC(=O)Cn1cnc(C#N)n1 +COc1ccc(-c2cncc(N(C)C)n2)c(OC)c1 +COC(=O)c1cc(-c2cc(C)cc(C)c2OC)on1 +CC(C)Oc1ccc(CSc2nnc(N)n2C)cc1 +CCNC(=O)c1ccc2cnn(Cc3ccc(C)cc3)c2c1 +O=C(Nc1ccccc1)Nc1cccc(N2CCOC2=O)c1 +Cc1n[nH]c(C)c1CCOC(=O)C1CCN(C(=O)N2CCCC2)CC1 +COC(=O)CNC(=O)c1cc(Br)c[nH]1 +COc1cccc(CN(C)C(=O)CNc2cc(F)ccc2F)c1 +CC(C)NC(=O)CN1C(=O)CCSc2ccccc21 +CNS(=O)(=O)C1CCCN(C(=O)Nc2ccc(Cl)c(F)c2)C1 +COC(=O)C(C)n1c(C(C)O)nc2cc(F)ccc21 +CC(C)CNC(=O)c1n[nH]c2c1CN(C(=O)OC(C)(C)C)CC2 +Cc1cc(C)n(C2CCN(C(=O)Nc3ccc4c(c3)CC(=O)N4)C2)n1 +N#CC1CN(C(=O)CCCc2cc(F)ccc2F)CCO1 +Cc1c(C(=O)Nc2cccc3c2C(=O)NC3)sc2ccc(F)cc12 +COc1cccc(OC(=O)Nc2ccc(SC)cc2)c1 +NS(=O)(=O)c1cc(C(=O)NCc2cccc3cccnc23)cs1 +COc1ccccc1C#CCNC(=O)COc1ccccc1 +Cc1ccc(OCC(=O)Nc2ccc(NC(=O)C3CC3)nc2)cc1 +Cc1ccccc1-c1ccnc2c1c(=O)n(C)c(=O)n2C +CCc1nc(CC(=O)OCc2nccn2C)cs1 +Cc1c(-c2ccncc2)n[nH]c1NC(=O)CNC(=O)CC(C)(C)C +CCOc1ccc(-c2c[nH]c(-c3[nH]cnc3C)n2)cc1 +CCCCS(=O)(=O)N1CCC(Cc2nc3cccnc3n2C)C1 +Nc1nccnc1C(=O)NCc1ncc(-c2ccccc2)o1 +Cc1cccc(C(NC(=O)NCc2ncn(C)n2)C(C)(C)C)c1 +CCCCn1nnnc1COc1nnc2ccccn12 +COc1ccc(Cl)cc1NC(=O)c1ccccn1 +O=C1CCN(C(=O)Cc2ccc3c(c2)CCC3)CC1 +CC(C)C(=O)Nc1ccc(C(=O)NC2(C(N)=O)CCCCC2)cc1 +N#CC1(NC(=O)Cc2cc3ccccc3[nH]c2=O)CCCCC1 +CC(Cc1ccccc1)NC(=O)CN1CCCC1=O +CCC(C)NC(=O)NCCCSc1ccc(F)cc1 +Cc1ccc2c(c1)c(=O)c(C(=O)Nc1ccc(C)c(C)c1)nn2C +Cc1cccc(C(C)CNC(=O)CSc2nncs2)c1 +COc1ccccc1NC(=O)c1nc2ccc(Cl)cn2c1C +CCN(CCO)c1nc(C)nc2sc3c(c12)CCC(C)C3 +Cn1c(=O)c(C#N)cc2cc(Br)ccc21 +O=C(COc1ccc(F)cc1)NCc1ccc(-n2ccnc2)cc1 +CCN(CC)C(=O)CSc1nc2ccc(Cl)cc2[nH]1 +COC(=O)c1ccccc1OS(=O)(=O)c1ccc(F)cc1F +CC(C)(C)n1cc(C(=O)Nc2scnc2-c2ccc(F)cc2)cn1 +O=C(C1CCOC1)N1CCC2OC(COCc3cccnc3)CCC21 +COc1ccc(C(=O)N2CCCC(c3nc(C)cs3)C2)nn1 +Cc1ccc(C)c(OCC(=O)Nc2cccn(C)c2=O)c1 +O=C(Cc1nnc(-c2ccsc2)o1)Nc1cccc(Cl)c1 +C#CCn1c(=NC(=O)c2cnccn2)sc2cc(OC)ccc21 +COC(=O)N(C)c1ccc(NC(=O)NC2CCCc3occc32)cc1 +O=C(NCc1ccco1)c1csc(NC(=O)c2ccccc2F)n1 +Cc1cc(C(=O)N2CCOc3cccc(F)c32)no1 +Cc1cc(NC(=O)c2cccc(N3CCCC3=O)c2)c2ncccc2c1 +O=C(c1ccsc1)N1CCCc2cccc(O)c21 +C=CCCS(=O)(=O)N1CCc2ccc(Cl)cc2C1 +COCCN1CCN(C(=O)c2nc(C(C)C)ncc2Cl)CC1=O +O=C(NCCc1ccc(F)cc1)Nc1ccccc1N1CCCC1=O +CC(C)CC(C#N)N(C)C(=O)COc1ccc(Cl)cc1 +Cn1ncc2c(NCc3ccc(F)cc3)nc(N3CCOCC3)nc21 +COc1ccc(CCCN2CCOCC2)cc1N +COc1cc(CCC(=O)Nc2ncccc2C)cc(OC)c1 +CC(=O)Nc1ccc(Cc2nc3c([nH]2)c(=O)n(C)c(=O)n3C)cc1 +CNS(=O)(=O)c1ccc(C(=O)Nc2cc(C)on2)o1 +O=C(Nc1cccc(-c2noc(-c3cnccn3)n2)c1)C1CC1 +CCC(=O)N1CCCCC1C(=O)NC(C)c1cc2ccccc2o1 +Cc1ccc(N2CC(C)N(C(=O)CNC(N)=O)CC2=O)cc1 +CC1CCC(O)(Cn2cnc3cnccc3c2=O)CC1 +O=C(c1cnn(-c2ccc(Cl)cc2Cl)c1)N1CCC(O)CC1 +Cc1csc(C(C#N)C(=O)C(C)NC(=O)c2ccccc2)n1 +CCOc1cc(C(=O)N(C)C)ccc1NC(=O)CC1=CCCCC1 +CCOCCNC(=O)N1CCCC(c2nc3ccccc3o2)C1 +CC(C)(C)C(=O)Nc1cccc(NCC(=O)NCC(F)(F)F)c1 +Fc1ccccc1-c1nnc(SCC2CCCO2)n1C1CC1 +CC(=O)Nc1c(-c2ccccc2)nc2c(C)cccn12 +COc1ccc(-n2c(O)cnc2Nc2nc(C)cc(C)n2)cc1 +Cc1cc(C(=O)NCc2ccc(C(C)(C)C)cc2)no1 +Cc1noc(N)c1C(=O)OCc1ccc(-n2cccn2)cc1 +COc1cc(OC)c(NC(=O)N2CCCC(O)C2)cc1F +COc1ccc(C(=O)NCc2cccnc2)c(OC)c1 +COc1cc(S(=O)(=O)NCC2CCCO2)ccc1Cl +O=c1n(Cc2cccnc2)nc(-c2ccco2)n1C1CC1 +CCc1nc(NC(=O)c2cc(OC)cc(OC)c2)sc1C +Cc1cc2[nH]c(=O)[nH]c2cc1C(O)Cc1ccccc1 +Cc1noc2ncc(C(=O)NCCOc3ccc4ccccc4c3)cc12 +CNC(=O)c1cc(C)ccc1NC(=O)c1cc(NC(C)=O)ccc1F +Clc1ccccc1CNc1c2c(nc3ncnn13)CCC2 +Cc1c(C(=O)NC2CCCC2)cccc1-n1nnc2cccnc21 +CCOc1cccc2c1OCC(=O)N(c1ccc(F)cc1)C2 +Cc1cc(C)n2nc(-c3cnn(C)c3C(F)(F)F)c(Cl)c2n1 +CCOc1ccc(OC)cc1NC(=O)CCc1cnn(C)c1 +CCOCC(=O)NCC#Cc1cccc(C(F)(F)F)c1 +O=C(OCc1cc2ccccc2[nH]c1=O)c1ccccc1Cl +Cc1ccc(C(N)=O)cc1NC(=O)N1CCOCC1 +C=CCNc1nnc(SCc2ccc(C#N)cc2)s1 +CCCCNC(=O)c1coc(CN2C(=O)CSc3ccccc32)n1 +CCCOc1ccc(OC(=O)C2CCN(c3ncccn3)CC2)cc1 +Cc1cc(CC(=O)N(C)Cc2cccc3cnccc23)on1 +O=C(c1cnc(N2CCCC2)nc1)N1CCN(c2ccccc2)CC1 +CC(C)=CCN1C(=O)C2CCC1CN(C(=O)CCn1cnnn1)C2 +N#CCc1nc2cc(F)ccc2n1-c1ccncc1 +CC(C)c1ccc(C2CCCN2C(=O)c2ccnnc2)cc1 +O=C(Cc1c[nH]cn1)NCC(=O)NC(c1ccccc1)c1ccccc1 +COC(=O)C(O)(CC(=O)Nc1ccc(C)cc1)C(F)(F)F +NC(=O)CSc1nnc(-c2cc(Cl)ccc2Cl)n1N +Cc1nocc1C(=O)N1CCCC2(CCN(c3ccccc3)C2=O)C1 +CCCNC(=O)c1cccc(C(=O)Nc2ccccc2OCC)c1 +CCN(Cc1ccccc1NCc1csc(C)n1)C(C)=O +CCCn1c(SCC(=O)Nc2ccccc2F)nnc1C(C)C +O=C(Nc1nccs1)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +CCOC(=O)C1CCCN(Cc2cnc3c(C)cccn23)C1 +CCOc1ccccc1C(=O)NCC(=O)Nc1ncccc1C +COc1ccc(CCCC(=O)NCC2CN3CCCCC3CO2)cc1 +COc1ccc(C2NC(=O)c3cccc(C)c3N2)c(OC)c1 +Cn1c(C(F)(F)F)nn(Cc2ccc(C#N)cc2)c1=O +Cc1nc(C2CCCN(S(C)(=O)=O)C2)cc(-n2ccnc2)n1 +COc1ccc(C(=O)N(C)c2cc(F)ccc2F)nn1 +Cc1cccc(S(=O)(=O)NCC2(O)CCOCC2)c1 +CNC(=O)C1CCC(NS(=O)(=O)c2ccccc2)CC1 +O=C(CSc1ccc(F)cc1)NCc1cscn1 +CCC1Oc2ccc(C)cc2N(CC(=O)N2CCNCC2)C1=O +O=C(NC1CN(Cc2ccc3c(c2)OCO3)C2CCCOC12)C1CC1 +CC(C)(C)c1ccc(CC(O)c2cnccn2)cc1 +Cc1cccc(C)c1NC(=O)CNC(=O)c1csc2c1CCCC2 +CCC(=O)Nc1ccc(C)c(NC(=O)NCc2cccc(OC)c2)c1 +O=C(CCCc1nc(-c2cccs2)no1)NCC1CC1 +Cc1ccc(NC(=O)C(C#N)Cc2ccc3c(c2)OCO3)cc1 +Cc1ccc(C(=O)NCC(=O)NCCCn2cccn2)cc1C +O=c1[nH]nc(CCc2ccccc2)n1Cc1ccccc1F +Cc1ccc(C(C)NC(=O)c2c[nH]c3ccccc23)o1 +CC(C)NC(=O)Nc1ccc(CNC(=O)N2CCCC(CO)C2)cc1 +CC(=O)Nc1ccc(Cl)c(NC(=O)C2CC3C=CC2C3)c1 +COc1c(C)cnc(CNC(=O)Nc2ccccc2SC)c1C +CC(=O)NC(C)(C)c1noc(CCCc2ccc(C)cc2)n1 +Cc1nn(C)c2nc(NC(C)c3nc(CC(C)C)no3)sc12 +FC(F)(F)Cn1cc(NCc2cnc(N3CCOCC3)nc2)cn1 +O=C1NCCN(C(=O)Cc2cccs2)C1c1ccccc1 +Cc1nnc(NC2CCCN(c3cnccn3)C2)o1 +N#Cc1cccc(S(=O)(=O)NCCc2cccc(Cl)c2)c1 +FC(F)(F)c1nn(-c2ccccn2)c2c1CNCC2 +Clc1ccncc1C1NCCc2ccc3c(c21)CCO3 +CCOc1ccc(CNC(=O)c2csc(-c3ccncc3)n2)cc1 +Cc1cccc(S(=O)(=O)Nc2ccc(F)cc2F)c1 +CCC(=O)N1CCN(c2nc3cccnc3n(C)c2=O)CC1 +Cc1cccc(NC(=O)c2ccccc2NC(=O)c2cnc(C)cn2)c1 +Cc1nnn2c1COC(CNC(=O)c1ccc[nH]1)C2 +CN(CC(=O)Nc1ccc(F)cc1)C(=O)c1ccc2c(c1)CCCC2 +Cc1cc(NC(=O)c2ccc(SCc3csc(C)n3)cc2)no1 +C=C(C)COc1ccccc1C(=O)N(C)CC(C)N1CCOCC1 +Cc1nccc(NC(=O)NC2CCCCNC2=O)c1Cl +CCn1cnnc1CNC(=O)N1CCOC(c2ccccc2Cl)C1 +Fc1ccc2nc(NCCn3cccn3)sc2c1 +COc1ccc(OC(=O)c2ccn(C)c(=O)c2)cc1C +COCc1cccc(NC(=O)C2(c3ccc(F)cc3)CC2)c1 +Cc1cc(NC(=O)C2CCCN2C(=O)c2ccco2)nc(C(C)C)n1 +Cc1nc(-c2cccnc2)sc1C(=O)NC(C)C +O=C(Cn1ncc2ccccc2c1=O)Oc1ccc2c(c1)CCC2 +CC(C)n1ncc2c(C(=O)Nc3ccccc3)cc(-c3ccco3)nc21 +CCN(CC)C(=O)COC(=O)c1cccc2[nH]ccc12 +CC1OCCN(Cc2cccc(OCCCC#N)c2)C1C +CN1CCOc2ccc(NC(=O)c3cccc4ccccc34)cc2C1=O +CCOC(=O)c1cc(-c2ccc(OC)c(OC)c2)on1 +Nc1c(Nc2ccc3c(c2)OCCO3)ncnc1N1CCCC1 +CCn1nc(-n2cnnc2)c(NC(=O)c2ccccc2C)c1C +CCn1cc(C(=O)N(c2ccccc2)C2CCN(C(C)=O)CC2)cn1 +O=C(NCc1ccc(Cn2ccccc2=O)cc1)C1CCOCC1 +CCc1ncc(C(=O)N(CCC(N)=O)Cc2ccccc2)s1 +CC(C)(C)c1ccc(OCC(=O)NCC(=O)NC2CC2)cc1 +Cc1ccc(S(C)(=O)=O)cc1S(=O)(=O)Nc1c[nH]nc1C +CCn1cnnc1CNC(=O)NC(C)c1cc(C)ccc1OC +CCC(C)NC(=O)Cn1cnc(-c2ccccc2)cc1=O +Cc1ccc(Cl)cc1NC(=O)C(C)Oc1ccc(C(N)=O)cc1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)NCC1CC1 +CC(=O)NCCCCCC(=O)N1CCCc2cccc(F)c21 +O=C(NCC(O)c1ccccc1C(F)(F)F)C1CCCC1 +CC(C(=O)Nc1nc(C(C)(C)C)cs1)n1cccn1 +COc1ccc(NC(C)=O)cc1NS(=O)(=O)c1cccs1 +CN(CC1CC1)C(=O)CCc1nc2ccccc2[nH]1 +Cn1ncnc1CNC(=O)CCSc1ccccn1 +O=C(NCCCc1ccccc1)Nc1c[nH]c2ccc(F)cc2c1=O +Cc1nc(-c2ccncc2)[nH]c(=O)c1CC(=O)Nc1cccc(F)c1 +Cn1cc(C2NCCc3c(O)c(Cl)cc(Cl)c32)cn1 +Cc1cccc(CN2CC(c3nc(-c4ncccn4)no3)C2)c1 +Cc1cc(NC(=O)NC(C)CCc2ccccc2)no1 +Cc1ccc(Cn2ncc3[nH]c(-c4ccc(-n5ccnc5)cc4)nc32)o1 +CC(C1CC1)N(C)S(=O)(=O)c1ccc2oc(=O)ccc2c1 +Cc1cccc(CN2CCN(C(=O)c3ccccc3O)CC2)c1C +O=C(OCC(=O)N1CCCCC1)c1cc(=O)[nH]c2ccccc12 +Cc1cncc(C2CCN(C(=O)c3cn(C)nc3C)CC2)n1 +COc1ccc2cc(C(=O)Nc3ccc(CC(N)=O)cc3)[nH]c2c1 +CC(C)n1nccc1C(=O)NCc1ccccc1F +O=S(=O)(C1CCOCC1)N1CCc2cc(F)ccc2C1 +C#CCNC(=O)c1ccc(F)c(S(=O)(=O)NCC=C)c1 +CC(C)c1cc(C(=O)N(C)CC(=O)Nc2cccc(Cl)c2)n[nH]1 +Cc1n[nH]c(N2CCN(c3cccc(Cl)c3)CC2)nc1=O +Cc1ccc(C(C)NC(=O)Nc2ccncc2)s1 +O=C(CCc1ccc(F)cc1)N1CCCC(O)C1 +Cc1cc2c(NC(=O)NC(C)Cn3nc(C)cc3C)cccc2nn1 +O=C(COCC1CC1)Nc1ccc(Br)cc1O +CCOc1ccccc1NC(=O)c1cccc(S(C)(=O)=O)c1 +COC(=O)C1CC(C#N)CN1C(=O)OC(C)(C)C +CCN(c1cc(C)ccc1C)S(=O)(=O)c1c[nH]c2ncccc12 +CCOc1ccc(NC(=O)Cn2nnc(-c3ccccc3)n2)cc1F +Cc1ccc(NC(=O)NC2(c3noc(C)n3)CCCC2)cc1 +CC(C)(CNC(=O)C1CCCCC1C(F)(F)F)C(N)=O +Cc1cc(C)cc(OC(=O)CCCNC(=O)C2CC2)c1 +CCOC(=O)CN(C)C(=O)CSc1cccs1 +CC1(C)CNC(=O)c2nc(Cc3ccncc3)[nH]c2C1 +CCn1cc(CCC(=O)Nc2c(C)nn(C)c2C(=O)OC)c(C)n1 +CC(CCN1CCOCC1)NC(=O)Cc1cccnc1 +Cc1cc(Br)cc(N)c1NC(=O)c1ccsc1 +COC(=O)C1CCCN(C(=O)Nc2ccccc2F)C1 +COc1ccc(OC)c(C2NC(=O)NC(C)=C2C(C)C)c1 +CCc1onc(C)c1NC(=O)C1(c2cccc(F)c2)CCOCC1 +O=C(COc1ccc(Cl)c(Cl)c1)NCc1ccco1 +Cn1cc(NC(=O)Nc2cccn(Cc3ccccc3)c2=O)cn1 +CC(C)c1nc(CN(C)C(=O)C2CCOC2)no1 +O=S(=O)(Nc1ccnn1Cc1ccccc1)c1ccccc1 +CCN(CC)S(=O)(=O)c1ccc(=O)n(CC(F)(F)F)c1 +Cc1noc(NC(=O)c2ccc(-n3ccnn3)cc2)n1 +CCC(C(N)=O)N1C(=O)CSc2ccc(N)cc21 +C=CCN(C)S(=O)(=O)c1ccc(NC(=O)c2ccccc2C)cc1 +COCCNC(=O)C1CCC(C)N(C(=O)COC)C1 +N#CC1(NC(=O)c2cn(-c3cccc(Cl)c3F)nn2)CCOCC1 +COc1ccc(C(C)NC(=O)Nc2ccc(F)cc2C#N)cc1OC +CS(=O)(=O)c1ccccc1SCC(=O)NCc1ccccn1 +CCCCC(=O)NC(C#N)c1ccc(OCC)cc1 +CCCn1cc(C(=O)N(C)Cc2n[nH]c3c2CCCC3)c(C)n1 +CC(C)CN(C)C(=O)c1cc(Br)cn1C +O=C(NCCOC(=O)c1cccc2ccccc12)c1ccncc1 +COC(=O)Cn1c(-c2ccc(N)cc2)csc1=O +COCCN(CC(C)C)S(=O)(=O)c1ccc(C)cc1 +Cc1nn(C)c(C)c1C(=O)NC(C)c1ccc2c(c1)CCCC2 +CCN(CC(=O)Nc1ccccc1OC)C(=O)CC(C)(C)C +O=C(Cc1ccc(-n2cnnn2)cc1)N1CCCC1 +C#CCn1c(C(C)NC(=O)C(C)(C)C)nc2ccccc21 +O=c1[nH]ccn1-c1ccc(NCc2ccco2)cc1 +COC(=O)N1CCC(CNC(=O)Nc2ccc(C)c(C)c2)CC1 +CC(C)CCC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +CC(NS(C)(=O)=O)C(=O)NCCOc1cccc(Cl)c1 +CCOc1ccc(-c2nc(C3CC3)n[nH]2)cc1OC +COCCn1cc(NC(=O)N2CCCC2c2ccc(OC)cc2)cn1 +Cc1csc(N(C(=O)Cc2csc(-c3ccco3)n2)C2CC2)n1 +CC1(C)CN(C(=O)C2CC(=O)N(c3ccccc3Cl)C2)CCO1 +CCOC1CCCN(C(=O)c2ccccc2OC)C1 +CCCC(=O)NCC(=O)N1CCC(Oc2ccccc2)CC1 +Cc1ccc(C(=O)Nc2ccc(NC(=O)c3cn[nH]c3)cc2)o1 +O=C(NCc1ccccc1)c1noc(-c2ccc3c(c2)OCO3)n1 +Cc1cc(NC(=O)c2cnc3ccccc3n2)ccc1N1CCCC1=O +COc1ccc(OC)c(CC(=O)Nc2ccccc2CC(N)=O)c1 +Cn1cc(-c2noc(-c3cccc(C(F)(F)F)c3F)n2)cn1 +CN(C1CCCCC1)S(=O)(=O)CCNC(=O)c1ccccc1 +O=C(Cc1ccccc1O)NCCc1cc(Cl)c2c(c1)OCCO2 +Cc1nnc(NC(=O)N(Cc2sccc2C)C(C)C)s1 +CCS(=O)(=O)NCc1cccc(OCc2ccccn2)c1 +Cc1cc(S(=O)(=O)N2CCN3CCCC3C2)c2ncccc2c1 +O=C(Cn1ncc2ccccc21)Nc1sccc1C(=O)NC1CC1 +CC(=O)c1ccc(Sc2nnnn2C2CCCC2)cc1 +CCC(=O)N(Cc1ccc(OC)cc1)C(C)C1CC1 +Cc1cc2c(cc1O)C(c1ncccc1Cl)NCC2 +O=C(NC(c1cccnc1)C(F)(F)F)c1cc(-c2ccccn2)n[nH]1 +CC(C)C(=O)N1CC2CCC1C2Oc1ccccn1 +CCOc1c(F)cccc1C(=O)N(C)C(C)CC +CN(CC1CCC1)C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +CC(c1ccccc1)n1cnnc1SCc1cccc(C(N)=O)c1 +O=C(COC(=O)C1CC1)Nc1nnc(-c2ccccc2)o1 +COCCn1nc(C(=O)Nc2ccc3c(c2)OCCO3)ccc1=O +O=C(CCc1cccc(F)c1)NCCNC(=O)c1ccccc1O +O=C(Nc1cccnc1)C1CC2OCCC2N(Cc2ccsc2)C1 +C=CCN(C(=O)c1cc(C2CC2)[nH]n1)C1CCCC1 +O=S1(=O)COCCN1CCCc1ccccc1 +Cc1cc(C(=O)NC2CCN(C(=O)C(C)C)CC2)no1 +CC(C)C(NC(=O)c1ccc2nc(-c3ccccc3)cn2c1)C(N)=O +Nc1c(Cl)cccc1C(=O)N1CCCCCC1 +CC(C)C1C(=O)NCCN1C(=O)Cc1ccc(F)cc1F +Cc1cc(=O)[nH]c(C2CCCN(C(=O)c3cnccn3)C2)n1 +COc1ccc(Cc2nc(-c3cccnc3)no2)cc1 +CC(=O)Nc1cccc(-c2cc(-c3nc(C)no3)ccn2)c1 +COc1cc(NC(=O)CSc2nncn2C)cc(OC)c1OC +N#CC(NC(=O)c1ccccc1F)c1ccccc1F +O=C(NCCCNC(=O)C1CCC1)c1cnc2ccoc2c1 +CNc1snc(C)c1C(=O)Nc1ccc(N(C)C(=O)OC)cc1 +Cc1nnc(SCC(=O)NC(C)(C)C)n1C1CC1 +N#CC(NCC(F)(F)F)c1ccc2c(c1)CCO2 +Cc1ccc(F)cc1NC(=O)CCNC(=O)c1ccoc1 +CC1CC1CNC(=O)COc1ccc2c(c1)CCC2 +Cc1ccc(SCC(=O)NCc2nnc3ccccn23)cc1 +C=CCn1c(SCCc2c(C)noc2C)nnc1-c1cnccn1 +COc1ccc(CN(C)C(C)CC#N)cc1OC(F)F +CCN(CC(F)(F)F)C(=O)c1cnn(-c2ccncc2)c1C +Nc1nc(Sc2nccc(C(F)(F)F)n2)nc2sccc12 +COc1ccc(S(=O)(=O)N2CCN(c3ccncn3)CC2)cc1 +CN(Cc1ccco1)C(C(=O)NC1CC1)c1ccccc1 +CCCc1nc(C(=O)NC(C)c2cn3ccsc3n2)cs1 +Cc1sc2nc(SCc3cccnc3)n(C(C)C)c(=O)c2c1C +O=C(Cn1ccc2ccccc21)NC1c2ccccc2CC1O +CC(=O)Nc1ccc(O)c(C(=O)NCCc2ccc(Cl)cc2)c1 +COCCCNC(=O)NCc1ccc(F)c(C)c1 +CNC(=O)c1cccc(NC(=O)c2cc(Cl)c(OC)c(OC)c2)c1 +Cc1ccccc1-c1nn2c(-c3ccccn3)nnc2s1 +Cc1ccc(Cl)cc1N1CC(C(=O)OCCn2cccn2)CC1=O +CCN(CC)S(=O)(=O)c1cccc(C(=O)Nc2cccnc2)c1 +CCCCN1CC(C(=O)N2CC(C)OC(C)C2)CC1=O +O=C(c1cc(-c2ccc(Cl)cc2Cl)on1)N1CCOCC1 +Clc1cccc(OC2CCN(CC3=CCCOC3)C2)c1 +CC(=O)NC(C)(C)c1noc(-c2ccc(F)c(F)c2)n1 +O=C(NCC1(c2ccc(F)cc2)CCCC1)c1ccccn1 +COC(=O)NCC(=O)N1CCCc2cc(F)c(F)cc21 +CC(C)CCNC(=O)C(N)c1ccc(O)cc1F +COc1ccc2[nH]cc(CC(=O)N3CCc4cc(F)ccc4C3)c2c1 +CC(C)CC(=O)N1CCCC(c2nn(C)c(=O)n2-c2ccccc2)C1 +CCCCNC(=O)c1sc(NC(=O)Nc2ccccc2)nc1C +COC(=O)c1c(NC(=O)CNC(=O)C2CC2)c(C)nn1C +CC(=O)N1CCCCC12CCCN(C(=O)c1cnccn1)C2 +CCc1nc2n(n1)CCCC2NC(=O)NCCN1CCOCC1 +CCCCOc1ccccc1NC(=O)c1csnn1 +CC(C)c1n[nH]c(SCC(=O)Nc2cc(Cl)ccc2C#N)n1 +O=C(Cc1ccc(F)cc1)Nc1nnc(C2CCCCC2)o1 +N#Cc1ccccc1OCC(=O)N(CCO)Cc1ccccc1 +N#Cc1cccc(CNCC(c2ccco2)N2CCCC2)c1 +O=C(NC1CCN(c2ccccc2)CC1)NC1CCCc2occc21 +CCOc1cccc(-c2nc3ccc(O)cc3c(=O)o2)c1 +COc1nc(N)nc2[nH]c(C(=O)OC(C)C)cc12 +Cc1cccc(C(CC(=O)Nc2nccs2)NC(N)=O)c1 +CSc1cccc(NC(=O)N2CCCC2c2ccccn2)c1 +Cc1cc(O)ccc1C1NCCc2ccc(F)c(F)c21 +COc1ccc(C(C)=O)c(OCC(=O)NC2CCCCC2)c1 +CCN(c1ccc(OC)nc1)S(=O)(=O)c1cccc(C#N)c1 +Cn1c(=O)[nH]cc(C(=O)NCc2cccnc2)c1=O +COC(=O)C(Nc1nccc2c(N)c(C)ccc12)C(C)C +CNC(=O)c1cc(NC(=O)NCC2CC2)ccc1Cl +CC(CC1CCCC1)C(=O)Nc1cccnc1-n1cccn1 +COc1ccc(CNc2cccc(N3CCCC3=O)c2)c(OC)c1 +CC(NC(=O)NC1CCCCC1)c1ccc(S(C)(=O)=O)cc1 +CC(C)C1(C)CN(CCO)c2ccc(Cl)cc2N1 +COc1ccc(C(=O)Nc2ccccc2OC(F)(F)F)cc1OC +Cc1cc(C)c2c(-n3cccc3)nn(CC(=O)N3CCCC3)c2n1 +CCCCNC(=O)N1CCOC(c2ccccc2)C1 +COC(=O)c1cc(Oc2ncnc3c2cnn3C)cc(C(=O)OC)c1 +Cc1cc(NC(=O)Nc2ccc(F)cc2)nc(C)n1 +COC(=O)c1ccc(OCC(=O)NC2(C#N)CCCCC2)cc1 +Nc1ccc2c(c1)CCCN2S(=O)(=O)c1ccc(F)cc1 +CCNC(=O)N1CCC(c2nc(C)ccc2C(=O)NCC(C)C)CC1 +Cc1ccc(NC(=O)Cn2ncc(=O)c3ccccc32)nc1 +Cc1n[nH]c(C)c1CCOC(=O)c1cc(N2CCNC2=O)ccc1F +C=CCn1cc(CN2CCCC(c3nc(C(C)C)no3)C2)c(C)n1 +CCOC(=O)C1=C(N)OC2=CC(C)=NC(=O)C2C1c1ccccc1 +COCC(C)(O)CNS(=O)(=O)c1cc(C)c(OC)c(C)c1 +COc1ccc2c(c1)nc1[nH]c(Nc3ccc(OC)c(OC)c3)nn12 +CN1CC(=O)N(c2ccccc2)CC12CCN(C(=O)C1CCCO1)C2 +CC(Oc1ccccc1C#N)C(=O)OCC(=O)NC1CCCCC1 +Cc1ccc(CNC(=O)Cn2c(=O)c(C)nc3cc(C)c(C)cc32)o1 +O=C(C1CN(Cc2ccccc2)CCO1)N(C1CCCC1)C1CC1 +Cc1cc(C(=O)N2CCC(c3nc(CC(C)C)no3)CC2)on1 +COc1ccccc1S(=O)(=O)Oc1ccc(F)c(F)c1 +Cc1ccsc1-c1nnc(SC(C)c2nc(C3CC3)no2)o1 +O=C(CC1CCCO1)Nc1c(N2CCCC2)cccc1N1CCCC1 +N#CCCn1c(Cc2cccs2)nc2cc3c(cc21)OCO3 +CCOc1nc(C2CC2)nc(NCc2ccncc2)c1N +CCC(Oc1ccccc1F)C(=O)N1CCN(CC)CC1 +CCC1COCCN1C(=O)Cc1c(C)nc2nc(N)nn2c1C +CC(OC(=O)c1nc(-c2cccs2)n(-c2ccccc2)n1)C(N)=O +O=C(c1ccc(OCC2CCCO2)cc1)N1CCOCC1 +Cc1nc2sccc2c(=O)n1NC(=O)C1CC2CCC1C2 +N#Cc1ccccc1COC(=O)c1cc(O)ccc1O +Cc1ncsc1CNC(=O)NCc1cc(=O)[nH]c2ccccc12 +NC(=O)C1CCN(C(=O)c2snc(-c3ccccn3)c2N)CC1 +CCc1csc(C2CCCN(C(=O)C(C)Oc3cccnc3)C2)n1 +CSc1ccccc1NCC(=O)N1CCc2ccccc21 +CC(C)C(=O)N1CCOc2ccc(C(=O)CN)cc21 +COCc1nnc(SCc2ccc(F)cc2)n1-c1ccccc1 +CC(CC(=O)N(C)c1ccccc1)Nc1cnn(C)c1 +COCC(=O)N1CCC(c2cncc(-c3cccc(Cl)c3)n2)CC1 +COc1ccc(CN(C)C(=O)CCSc2nnnn2C)cc1 +C#CCOc1nnc(-c2ccc(Cl)cc2)s1 +O=C(Nc1cnn(CC2CCCO2)c1)Nc1ccc(Cl)cc1F +COc1ccc(CN2CCn3c(nn(C)c3=O)C2)cc1F +CC(=O)c1ccc(OCc2nnc(-c3cccc(F)c3)o2)c(C)c1 +Cc1cccc(OC(=O)C2CCN(C(=O)N(C)C)CC2)c1 +COc1cccc(Cn2cc(NC(=O)Cc3ccc(F)cc3)cn2)c1 +O=C(NCCCn1ccc2cccnc21)c1cc(-c2ccco2)on1 +COCCn1c(SC(C)C(C)=O)nc2cc(Cl)ccc21 +CC(C)N(C)C(=O)c1ccc(=O)n(-c2ccc(F)cc2)n1 +C=CCCCN(C)C(=O)CNC(=O)c1ccc2c(c1)OCO2 +CC1CCN(C(=O)CSc2nnc(-c3cccnc3)n2C)CC1 +Cc1nc2sccc2c(=O)n1NC(=O)COc1ccccc1 +c1ccc(OCC2CC2)c(CN2CCOC(c3nccs3)C2)c1 +Cc1n[nH]c(Nc2ccc(OC(F)F)cc2)nc1=O +COC(=O)C1(NC(=O)c2cc(C)sc2C)CCCC1 +COc1ccc(-c2ccc(=O)n(C(C)C(=O)NCC(N)=O)n2)cc1 +Cc1cc(Br)ccc1N(CCO)CCO +CN1CCN(C(=O)c2cn(C)c3ccccc23)CC1 +O=C(Nc1ccnn1-c1cccc(Cl)c1)C1CC=CC1 +COCCNC(=O)N1CCN(CC(=O)N(C)C2CCCCC2)CC1 +CC1CC1c1ccc(CN(C)S(=O)(=O)c2ccc(C(N)=O)cc2)o1 +CC(CCOc1ccccc1)C(=O)Nc1nc2ccc(F)cn2n1 +Cc1n[nH]cc1NC(=O)c1cc(Cl)ccc1F +CC1CC1C(=O)N1CCCC1C(=O)Nc1nccs1 +COc1ccc(OC)c(Cn2cc(CCO)nn2)c1 +O=C(NCC(=O)N1CCc2nocc2C1)c1ccccc1Cl +Cc1cc(C(=O)Nc2cccc3[nH]ccc23)c2c(C)nn(C)c2n1 +CC(=O)Nc1cc(NCc2cnn(-c3ccccc3)c2)ccc1F +COc1ccc(CCNC(=O)c2nc(-c3cccs3)no2)cc1 +CS(=O)(=O)c1ccccc1NC1C=CCCC1 +O=C(Cc1c[nH]c2ncccc12)NC(CO)c1ccccc1 +CCNC(=O)CN(C)C(=O)Cn1cc(Br)ccc1=O +O=C(NCc1noc(Cc2cccc(Cl)c2)n1)c1ccccc1 +C=Cc1nnc(C(N)c2ccc(C#N)cc2OC)o1 +C#CCNC(=O)CSc1nnc(C(C)(C)C)n1N +Cc1ccc(NC(=O)N2CCCCC2CN2CCCC2=O)c(Cl)c1 +CCc1cc2c(NCc3c[nH]nc3C)ncnc2s1 +Cc1noc(C)c1C(=O)N(C)Cc1ccc2c(c1)OCO2 +COc1ccc(CNC(=O)c2ccncc2)c(OC)c1OC +CCCC1(C)Oc2cc(N)c(Cl)cc2NC1=O +CCOc1cc(CO)ccc1OCC(=O)Nc1cccc(C)c1 +COc1cc(F)ccc1NC(=O)CCNC(=O)NC1CCCCC1 +CC1CCCCN1C(=O)c1cc(-c2ccc3c(c2)OCO3)on1 +CC=CCCNS(=O)(=O)c1ccc(N2CCOC2=O)cc1 +CCOCCC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +O=C(CCc1ccc(F)cc1)Nc1cnn(CC2CC2)c1 +COC(=O)c1cc(C#N)c(=O)n(CC(C#N)CCC#N)c1 +COc1ccc2c(CC(=O)Nc3nnc(C(C)C)s3)coc2c1 +Cc1csc(C(C)(C)NC(=O)c2c[nH]c3cccc(F)c23)n1 +O=C(CN1CCN(c2ncccn2)CC1)NCCN1CCOC1=O +CC(=O)N1CCCC1C(=O)NCCc1ccccc1Cl +Cc1c(C)c2cc(Cl)c(OCC(N)=O)cc2oc1=O +O=C(c1cc(-c2ccncc2)on1)N(Cc1ccccc1)CC1CCC1 +CCCC(NC(=O)Cn1cccn1)C(=O)N1CCc2sccc2C1 +COc1cc(C(C)Nc2ccc3nnnn3n2)ccc1OCC(C)C +COC(=O)CCC(=O)Oc1ccc(Br)cc1 +CCC(=O)N1CCC(NC(=O)c2cccnc2)CC1 +COc1ccc(C(C)NC(=O)Nc2ccc(OC)c(OC)c2)cc1F +COCCNC(=O)Cc1coc2cc3c(cc12)CCC3 +O=C(Nc1ccccc1CO)OCc1ccccc1 +CC1=C(C(N)=O)C(c2ccco2)C(C(N)=O)=C(C)N1 +CC(C)(O)CN1CCN(C(=O)NCc2cccnc2)CC1 +CCCOc1ccc(C(=O)Nc2ccccc2N)cc1 +COc1c(NC(=O)C2COc3ccc(F)cc3C2)c(C)nn1C +Cc1nc(C2CC2)nc2sc(C(=O)c3cc(C)n(C)c3C)c(C)c12 +Nc1ccc(F)c2ccnc(C(=O)N3CCCCCC3)c12 +Cc1cc(F)c2c(c1)CCCN2CC(=O)N(C)C +COc1cccc(C(=O)CSc2nnc3[nH]c4ccccc4n23)c1 +COc1cccc2ccc(-c3nn4c(C)nnc4s3)nc12 +Cc1cc(NC(=O)CC2Sc3ccccc3NC2=O)no1 +O=C(CNC(=O)c1cccn1Cc1ccccc1)NC1CCCCC1 +Cc1cc(C)n2ncc(-c3noc(CNS(C)(=O)=O)n3)c2n1 +Cc1ccc2nc(C)c(C)c(C(=O)N3CC(c4ccccn4)C3)c2c1 +CC(=O)Oc1ccc(C(=O)n2nnc3cc(C)ccc32)cc1 +CC(OC(=O)c1c[nH]c(=O)c(Cl)c1)c1ccc(F)c(F)c1 +O=C(Nc1ccccc1F)Nc1cc(Cl)ccc1-n1cncn1 +COc1ccc(C(=O)OCc2cc(=O)n3nc(C)sc3n2)cc1 +COc1ncccc1C(=O)N1CCCN(Cc2cccs2)CC1 +CCOC(=O)c1ccccc1NC(=O)Cc1ccc2c(c1)OCCO2 +CC(=O)c1c(C)nc(C)nc1SCC(=O)NC(C)c1ccccc1 +Nc1onc(CCc2ccccc2Cl)c1-c1ccccn1 +O=C(Cc1ccc(O)cc1)NCCc1ccc(O)cc1 +CCOc1ccc(NS(=O)(=O)Cc2ccccc2F)cc1 +N#CCCNC(=O)COC(=O)c1ccc(N)c(F)c1 +NC1=Nc2nc3ccccc3n2C(c2cccnc2)N1 +O=C(NCCCn1nccc1C1CC1)c1cn2ccsc2n1 +CCN(CC(=O)NC)C(=O)c1cnn(-c2ccccc2Cl)c1 +CC1CC(N2CCN(C(=O)c3ccc(F)cc3Cl)CC2)C(=O)O1 +CS(=O)(=O)c1ccc(CC(=O)Nc2cnc3n2CCCC3)cc1 +Cc1cccc(C(C)C)c1NC(=O)NCc1cccc(C#N)c1 +CC(c1ccccn1)N(C)C(=O)Nc1ccc(Cl)c(F)c1 +CCn1cc(C(=O)Nc2cccnc2)c(=O)c2cc3c(cc21)OCO3 +CCn1cc(C(=O)N2CC(C)CC(C)C2)c(=O)c2c(N)cccc21 +CC(C)Nc1ncnc(Nc2ccc(Br)cn2)c1N +Nc1ccc2c(c1)N(C(=O)CC1CCCC1)CCS2 +CN(C)c1ncc(C(=O)c2cnc(N(C)C)s2)s1 +COc1cc(F)c(NS(=O)(=O)c2ccc(F)cc2)cc1OC +CCOc1ccc(C(=O)NCC2COc3cc(OC)ccc3C2)o1 +Cc1cc(NC(=O)C2CC2)sc1C(=O)N1CCOCC1C1CC1 +Cc1nc(CCNS(=O)(=O)N2CC(C)CC(C)C2)cs1 +Cc1oc(C(=O)Nc2cc(Cl)cc(Cl)c2)cc1S(N)(=O)=O +Cc1cc(CN(C)C(=O)c2occc2COc2ccccc2)no1 +C=C(C)CN(CC)C(=O)NCC(C)(C)NS(C)(=O)=O +C=CCn1c(SCC(N)=O)nnc1-c1ccco1 +CC(C)c1ocnc1C(=O)NCCc1ccn(-c2cccc(F)c2)n1 +CC(C)CC(NC(=O)NCC(F)(F)F)c1ccccc1 +Nc1nccnc1C(=O)NC1CCSc2ccc(Cl)cc21 +NC(=O)c1ccc(S(=O)(=O)N2CCNCC2)cc1 +CCC(NC(=O)N1CCCC1)c1cccc(Cl)c1 +CC1COCC(C)N1Cc1nn(-c2ccc(F)cc2)c2c1CCC2 +Cc1cc(C)n(CC(=O)Nc2cccc(N)c2)c(=O)n1 +CN(C)C(=O)CNS(=O)(=O)c1ccc2c(c1)OCCCO2 +CCC(C)n1nccc1NC(=O)Cc1ccc(C)c(OC)c1 +O=C(CCCNC(=O)c1ccc(F)cc1)Oc1ccccc1Cl +CC(NC(=O)N1CCOCC1C)c1ccc(-c2cccnc2)cc1 +O=C(Cc1ccccn1)N1CCC(O)C1Cc1ccncc1 +O=C(NC1CC(=O)N(c2ccc3c(c2)OCCO3)C1)N1CCCC1 +Cc1cc(CNc2ccc3[nH]ncc3c2)c(C)s1 +COC(=O)CCC1CCN(C(=O)C2COc3ccc(F)cc3C2)CC1 +CC(Nc1nccn(C)c1=O)c1ccc(Cl)cc1 +COC(=O)c1ccc(Cn2cc(-c3nc(C)no3)ccc2=O)o1 +CC(=O)c1ccc(S(C)(=O)=O)c(N2CCc3cccc(F)c3C2)c1 +c1ccc2c(c1)nc(Nc1ccc3c(c1)OCO3)c1nncn12 +CC(=O)NCCNC(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1 +CCOc1ccc(OCC(=O)N2CC(C)OC(C)C2)cc1 +N#Cc1c(CSc2ncnc3sccc23)cn2ccccc12 +CN(C(=O)Cc1ccc(F)cc1)c1cccc(C#N)c1 +Cn1cc(CC(=O)NCc2ccncc2)c2ccccc21 +Cc1nc(C(=O)N2CCCC(NS(C)(=O)=O)C2)cs1 +O=C(Nc1ccncc1)Nc1cnn(-c2ccccc2F)c1 +CCOC(=O)c1cnc2c(c1)c(C#N)cn2CC(=O)Nc1cccnc1 +FC(F)(F)CN1CCCN(Cc2nnnn2C2CC2)CC1 +Cc1cc(N)ccc1C(=O)N1Cc2ccccc2C1 +COc1ccc(NC(=O)N2CCN(c3ccccc3)CC2)c(OC)c1 +Nc1cccc(CCC(=O)NCCc2ccc(Cl)cc2)c1 +COc1ccc(NS(=O)(=O)c2cn(C)nc2C)cc1OC +CS(=O)(=O)c1ccc(F)c(NC(=O)CCCc2cccs2)c1 +C#CCOc1ccc(N(C)C(=O)c2ccncc2Br)cc1 +CC(=O)c1cc(-c2ncnn2C2CCCCC2)[nH]n1 +Cc1ccc(NC(=O)CSc2ncc(F)c(N)n2)cc1C +NC(=O)c1cc2c(cc1Br)CCCC2 +CN(Cc1cnn(C)c1)C(=O)COc1ccc(F)c(F)c1 +CSc1nc(C)c(CCC(=O)Nc2ccccc2C#N)c(C)n1 +CC(C)N(C(=O)CSc1nc(-c2cccnc2)n[nH]1)C1CCCC1 +COC(=O)C(c1ccc2c(c1)OCCCO2)C1CC1 +Cc1ccc(-c2n[nH]c(NC(=O)c3ccc(N(C)C)cc3)n2)cc1 +Cc1cc(C)c(NC(=O)C2CSc3ncc(C)c(=O)n3C2)c(C)c1 +CC(C)(C)OC(=O)NCc1ccc2c(c1)OCO2 +N#Cc1ccccc1CNC1(c2ccc(F)cc2F)CCOCC1 +O=C(Nc1ccc(Cn2cncn2)cc1)c1ccc(Cl)cc1 +O=C(Cc1ccc(F)cc1)Nc1cccc(N2CCOC2=O)c1 +CC1=Nc2nnnn2C(c2ccccc2Cl)C1C(N)=O +CC(C)NC(=O)CCNC(=O)NC1CCc2c(Cl)cccc21 +Cc1ccc(C)c(C(=O)N2CCCC(c3nc(C)no3)C2)c1 +COC(=O)CCC(N)C(=O)c1ccc(OC)cc1 +O=S(=O)(Nc1ccc(-c2ccn[nH]2)cc1)c1ccc(Cl)cc1 +N#Cc1ccnc(SCC(=O)c2cccc(N3CCCC3=O)c2)c1 +COc1cc2c(cc1CN1CC3(CCOC3)CCC1=O)CCC2 +CCC(=O)Nc1cc(C)ccc1NC(=O)c1ccco1 +CCOc1ccccc1-c1ccc(CO)c(=O)n1CC(C)C +O=C(NCCSc1ccccn1)OCC(F)(F)F +O=C(NCc1cscn1)C1CC1c1cccc(Cl)c1 +COc1ccc(F)cc1-c1cc(C)n(C(C)C)c(=O)c1C#N +CC1CCCN(C(=O)CNc2cccc(-n3cnnn3)c2)C1 +COc1ccc(Cl)cc1-c1nn2c(-c3cnccn3)nnc2s1 +N#Cc1csc(CCOc2ccc(Br)cc2)n1 +COc1ccccc1CC(=O)NC1CCCc2cn[nH]c21 +CN(C)S(=O)(=O)N1CCCC1c1ccc(C(C)(C)C)cc1 +Cc1cccc(-c2nc3cc(C)cnc3n2CCC#N)c1 +CCC(CC)NC(=O)c1ccccc1SCC(=O)N1CCCC1 +Cc1noc(C)c1C1CCCN1C(=O)C1CCCC1 +COC(=O)CN(C)S(=O)(=O)c1ccc(C)cc1Br +CCC(NC(=O)N(C)Cc1c(C)noc1C)c1ccc(OC)cc1 +O=C(CCn1cncn1)Nc1ccc2c(c1)CCC2 +COc1ccc2c(CC(=O)NCCc3cccs3)coc2c1 +NC(=O)C1(CNC(=O)C2CC=CCC2)CCOCC1 +Cn1nc(CNC(=O)C2CC2)c2ccccc2c1=O +Cc1ccc(NC(=O)CCNS(=O)(=O)c2cccs2)c(O)c1 +Cc1cccn2cc(CSc3ccccc3S(C)(=O)=O)nc12 +CCC(C)n1nc(-c2ccccc2)cc1S(N)(=O)=O +CNC(=O)Cc1nc(CNc2cc(F)c(F)cc2F)cs1 +Cc1nc(C)c(C(=O)Nc2cncnc2N2CCCC2)s1 +O=C(NCCCO)c1ccc(F)c(S(=O)(=O)N2CCCCC2)c1 +CCC(NC(=O)OC(C)(C)C)c1nc(C)cc(C)n1 +COC(=O)C1CN(Cc2cccc(C)c2)CCC1=O +CSc1cc(C(=O)N2CCC(C)CC2C)ccn1 +COc1ccnc(NC(=O)c2cnc3onc(C)c3c2)c1 +CN(C)C(=O)C1CC2CN(C(=O)NCC3CCCCC3)CC1O2 +COc1cccc(CNC(=O)c2cc(F)ccc2Cl)c1 +CCCc1nnc(N2CCN(Cc3cccc(Cl)c3)CC2)o1 +CCOCC(=O)N(Cc1cccs1)c1ccc(OC)cc1 +C=CCNC(=O)c1cc2cccc(CC=C)c2oc1=O +CCCCCNC(=O)C1CC(=O)N(c2ccc(C)cc2C)C1 +COc1ccc(C)cc1-n1ccc(C(=O)N2CC(n3ccnc3)C2)n1 +COC(=O)NCC(=O)N(C)CCc1ccccc1 +Cc1occc1CN(C)C(=O)c1[nH]nc2c1CCCC2 +CC1CC1C(=O)NCCC(=O)Nc1ccc2oc(=O)ccc2c1 +COc1ccc(CNC(=O)c2c(C)cc(C)[nH]c2=O)cc1C +COc1cccc(CNc2nc(SC)ncc2CO)c1 +CS(=O)(=O)N1CC2CCC(C1)N(C(=O)NCc1cccs1)C2 +CCOC(=O)N1CCC(NC(=O)c2oc3c(F)cccc3c2C)CC1 +CC(=O)N1CCN(C(=O)CCCNC(=O)c2cccs2)CC1 +N#Cc1nc(C2CC2)oc1N1CCN(C(=O)C2CC=CCC2)CC1 +O=C(Nc1cccc(F)c1)c1cc(Cl)c2c(c1)OCO2 +CC1(C)COCCN1C(=O)c1[nH]nc(C2CC2)c1Br +CC1CCN(C(=O)c2cnc(C3CCCO3)nc2N)CC1 +Cc1ccc(Cl)c(OCC(=O)NC(C)(C)CO)c1 +c1c(-c2nc3c4c5c(sc4ncn3n2)CCC5)n[nH]c1C1CC1 +C=CCNC(=O)CN(c1ccc2c(c1)OCO2)S(C)(=O)=O +Cn1nccc1CNC(=O)CCCc1cccs1 +CC(=O)N1CCN(C(=O)C2CC2c2ccccc2)CC1 +CC(OC(=O)c1cccc(-n2cnnn2)c1)C(=O)c1ccccc1 +CCn1ncc(NC(=O)c2cc(-c3ccc(C)cc3)on2)c1C +Cc1ccc(S(=O)(=O)CC(=O)N(C)Cc2cccs2)cc1C +CCCCN1CC(C(=O)Nc2c(CC)cccc2CC)CC1=O +CCNC(=O)CNC(=O)NC1CCCCC1CC +COc1ccc(NC(=O)NCC(=O)NC2CCCCC2)cn1 +C=CCNC(=O)c1ccc(N(C)CCC(=O)NC)nc1 +O=C(COC(=O)Cc1ccsc1)NC1CCCCCC1 +CCC(C)(NC(=O)c1ncn(-c2ccccc2)n1)c1nc(C)cs1 +C=CCn1c(N)nnc1SCc1nccn1C(F)F +CCN1C(=O)CC(c2ccccc2)Sc2ccccc21 +CC(C)NC(=O)c1nc(-c2ccc(C(F)(F)F)cc2)no1 +NC(=O)c1cc(S(=O)(=O)NC2CCCC2)cs1 +Cc1sc2nc(CSc3nncs3)[nH]c(=O)c2c1C +Cc1nc2ncc(C(=O)NCC(O)c3ccccc3Cl)cc2[nH]1 +COC(=O)CN(c1ccccc1F)S(=O)(=O)c1ccc(C)cc1 +COc1cc2c(c(Cl)c1OC)CCNC2c1cc[nH]n1 +CCCNC(=O)C(CC)n1nc(C)n2c(cc3sccc32)c1=O +Cc1nc(C)c(C(=O)N2c3ccccc3N(C)CCC2C)o1 +Nc1ccc2c(c1)CC(=O)N2Cc1ccc(Cl)cc1Cl +COc1ccc(C(=O)N2CC3CC=CCC3C2)c(O)c1 +Cc1ccsc1CNC(=O)Cc1c(C)noc1C +COc1cccc(CC(=O)Oc2ccc(C)cc2OC)c1 +O=C(Nc1ccc(-n2cnnn2)cc1)c1ccc(N2CCCC2)nn1 +CNC(=O)c1cc(OC)ccc1NC(=O)c1cc(C)n(C(C)(C)C)n1 +Cc1n[nH]c(C)c1CCC(=O)Nc1ccc(-n2cncn2)cc1 +Cn1cc(Cl)cc1CNC(=O)c1cccnc1SC1CCCC1 +COCc1oc(-c2ccc(OC)c(Cl)c2)cc1C#N +CCOC(=O)C(C)CN1CCN(S(C)(=O)=O)CC1 +COc1ccc(Nc2nccc(C(F)(F)F)n2)cc1OC +Cc1oc2ncn(CC(=O)NCCC3=CCCCC3)c(=O)c2c1C +Cc1ccc(C(=O)OCC(=O)Nc2ncc(Cl)cc2Cl)o1 +CCCOc1ccc(C(=O)Nc2nc(C)cs2)cc1OCC +CCOc1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)cc1 +Cc1ccc2c(c1)[nH]c(=O)c1c(C(=O)NCC3CCCO3)nnn12 +CCC(C)NC(=O)NC1CCN(C(=O)NC2CCCCC2)CC1 +COCCCNC(=O)Nc1cc(-n2cnnn2)ccc1C +CCS(=O)(=O)N1CCC(Nc2ccccc2OC)CC1 +COC(=O)C1(NS(=O)(=O)c2c(C)nn(C)c2C)CCCCC1 +CCNC(=O)Nc1ccc(OCC(=O)NCc2ccco2)nc1 +COc1ccccc1NC(=O)C1COc2ccccc2C1 +Cc1nc(-c2cccc(NC(=O)C3CCC3)c2)no1 +Cc1cc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)on1 +CCOCC1CCCN(C(=O)Nc2cc(C)ccc2F)C1 +CCN(C(=O)c1cccc(C(=O)OC)c1)C1CCCC1 +COc1ccc(C(=O)N(C)C)cc1NCC(=O)NCC(F)(F)F +O=C(NCCN1CCCCCC1=O)c1cncc(Br)c1 +COC(=O)Cc1c(O)ccn(Cc2ccc(C)o2)c1=O +COc1ccc(CCCCC(=O)N2CCCC2C(N)=O)cc1 +CC(=O)N1CCC2(CC1)CNc1ccc(Cl)cc1N2 +O=C1CCC(COC(=O)c2cccc(-n3cnnn3)c2)N1 +Cc1ccn(C(=O)COc2ccc(Cl)cc2)n1 +O=C(c1cccs1)N(Cc1ccco1)Cc1cccs1 +O=C(c1cnc2ccccc2n1)N(Cc1ccco1)Cc1ccco1 +CCc1noc(-c2c(C)cc(C)n2CC(=O)NC2CCCCC2)n1 +CNS(=O)(=O)c1cc(NC(=O)c2cccc(N(C)C)c2)ccc1C +Cc1ccc(NC(=O)Cc2ccc[nH]2)cc1N1CCOC1=O +OCCN(Cc1ccncc1)Cc1cc(Br)ccc1F +CCn1ncc(-c2ccc(OC(C)C)cc2)c(C(C)=O)c1=O +CSc1ccccc1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CC(O)(CNC(=O)NCc1cccnc1)c1ccccc1 +Cc1noc(CNC(=O)COc2ccccc2C)n1 +CN(Cc1nnc2n1CCC2)C(=O)c1ccc(Cl)cc1Cl +O=C(Nc1ccccc1)c1ccc(=O)n(Cc2cccc(F)c2)n1 +CCc1nc2c(cnn2-c2ccccc2)c(=O)n1CCOC +COC(=O)c1cc(F)c(C)c(NC(=O)NC(C)C)c1 +COc1cccc(CCCNc2ccc(C#N)cc2)c1O +CCCCn1c(SCc2nc(-c3ccsc3)no2)n[nH]c1=O +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)N(C)C1CC1 +CN(Cc1cccc2ccccc12)C(=O)c1ccsc1 +Cc1cc(NC(=O)c2ccc(S(=O)(=O)N(C)C3CC3)cc2)n(C)n1 +Cc1ccc(C(C)OC(=O)C2CC(=O)N(CC(F)(F)F)C2)cc1 +CCNC(=O)Cn1ccc2ccc(OC)cc2c1=O +Cc1ccc(S(=O)(=O)N2CCN(CCc3ccccn3)CC2)cc1 +Cc1cccc(C(O)c2cc(C)c3c(c2)CC(=O)N3)c1 +CC(NC(=O)CSc1nncn1-c1ccccc1F)c1ccco1 +O=C(Nc1ccc(Cn2cncn2)cc1)c1scnc1C1CC1 +COc1cccc(CNC(=O)C2COC(=O)N2CC2CCOC2)c1 +CCc1nc(NCC(C)O)c(C#N)c2c1CCCC2 +Cc1nc(-c2cc3c(cc2F)NC(=O)CC3)cs1 +CC(C)CC(=O)NCC1CCN(C(=O)Oc2ccccc2)CC1 +Cc1ccc(CNC(=O)Cc2nnc(-c3ccccn3)o2)cc1C +C=CCOc1c(CN2CCOCC2CC)c(C)nn1C +O=C(c1ccc(F)cc1)N1CCN(Cc2c[nH]c3ccccc23)CC1 +COC(=O)c1cc(C)ccc1OCC(=O)Nc1cc(C)nn1C +CCC(OC)C(=O)Nc1cc(NC(C)=O)c(F)cc1F +O=C(CNC(=O)c1ccoc1)Nc1ccc2c(c1)OCO2 +O=C(Nc1ccc(O)cc1)c1cc(-c2cccnc2)nc2ccccc12 +CC(C)NC(=O)Cc1cc2c(s1)CCCC2=O +CC1CCCC(OC(=O)c2ccc(=O)n(-c3ccc(F)cc3)n2)C1 +Fc1ccc(-n2cccn2)c(NCc2noc(-c3ccccc3)n2)c1 +CCCCn1c(N)c(N(C)Cc2noc(C3CC3)n2)c(=O)[nH]c1=O +N#Cc1ccc(OCCOC(=O)c2ccccn2)cc1 +CC(C)c1ccc2c(c1)CCCN2C(=O)C1CC(=O)N(C)C1 +CC(C)(CNC(=O)c1cc(F)cc(F)c1)N1CCOCC1 +CCCc1cc(C(=O)Nc2ccc(C(N)=O)cc2)sc1C +CC(=O)N1CCC(C(=O)N=c2[nH]ccn2Cc2ccccc2)CC1 +Fc1ccc(-n2ncnc2C2CCCCO2)cc1Cl +CC(C)(C)OC(=O)N1CCC(Cc2ccccc2)C(O)C1 +Cc1onc(-c2ccccc2F)c1C(=O)NCCC(C)C +Cc1ccc(C(C)NC(=O)c2ccc(S(=O)(=O)N(C)C)o2)o1 +CSc1nnc(C(=O)NCc2ccccc2)n1C +COC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccccc1 +Cc1ccc(C(=O)CCC(=O)Nc2c(C)cccc2C)cc1C +CC(C)(Cn1cc(Cl)ccc1=O)C(=O)Nc1ccccc1N +Cc1nnc(NC(=O)NCC(=O)Nc2ccc(Cl)cc2)s1 +COc1ccccc1CN1C(O)c2ccccc2S1(=O)=O +COc1ccc(C(C)=O)c(OCC(=O)NC(C)c2ccccc2)c1 +Cc1cc(CN2CCN(S(=O)(=O)NC3CC3)CC2)on1 +NC(=O)c1n[nH]c2ccc(NCC3CC=CCC3)cc12 +COC(=O)c1sccc1NC(=O)CN(C)c1ccccc1OC +Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cnccn3)CC2)cc1 +CCCC(C(=O)N1CCNC(=O)C1)c1ccccc1 +Cc1sc2ncn(Cc3cc(F)cc4cccnc34)c(=O)c2c1C +COc1cccc(NC(=O)CSc2ccc(N)cc2)c1 +Cc1cc(C)n2nc(SCC(=O)Nc3nnc(C(C)C)o3)nc2n1 +COCC(NC(=O)NCc1ccco1)c1cccc(C(F)(F)F)c1 +CC(C)C(=O)Nc1ccc(NC(=O)CN2CCc3ccccc32)cc1 +COc1ccccc1Oc1ncccc1CNc1nc(C)ccc1C#N +Cc1cc2c(N)cccc2c(C(=O)Nc2nnc(C(C)C)s2)n1 +Cc1cc(C)c(C(=O)NC2CCCCC2O)c(C)c1 +NC(=O)c1ccc(C#CCNC(=O)Cc2ccccc2Cl)cc1 +CC1CN(CC(=O)NCc2cccs2)CCN1c1nccs1 +Cc1ccc(C(=O)N(C)C)cc1OC(=O)c1cc(C(N)=O)cs1 +CC(C)CCNC(=O)CCn1ncc2ccccc21 +O=C(Nc1nccs1)C1CCCN1C(=O)C1CC1 +OC1Cc2ccccc2C1Nc1ccc(Br)cn1 +CC(C)CC(=O)OCc1nnc(-c2ccccc2)o1 +O=C(NCCc1ccccc1F)NCC1CN2CCCCC2CO1 +CC(Cc1ccc(Br)cc1)NC(=O)c1n[nH]c(=O)[nH]1 +O=C(CCNC(=O)c1ccc(O)c(Cl)c1)Nc1ccncc1 +Cc1cnc(NC(=O)c2csc3ccccc23)s1 +Cc1csc(COC(=O)c2cc3c(cc2F)NC(=O)CC3)n1 +Cc1ccc2[nH]c(C(O)C(O)c3nc4ccc(C)cc4[nH]3)nc2c1 +Cn1ccsc1=NC(=O)Cc1ccc(F)cc1 +O=C1CCCC1Sc1nnc(-c2c[nH]c3ccccc23)n1C1CC1 +CCNc1ncc(C(=O)N2CC3CCC2CN(C(=O)N(C)C)C3)cn1 +CN(CC(=O)Nc1cccc(Cl)c1)C(=O)OC(C)(C)C +Cc1ccncc1NC(=O)NCCCn1c(C)nc2ccccc21 +CC(Sc1nnc(-c2cnccn2)o1)C(N)=O +CC(C)N(C)S(=O)(=O)NCCC(=O)N1CCCCC1 +Cc1ccc(C)c2c1CCNC2c1cccnc1F +CC(C(=O)N1CCc2cc(C(C)(C)C)ccc21)n1cncn1 +CCC(C)NS(=O)(=O)c1ccc(N)c(Br)c1 +CC(=O)Nc1cccc(COC(=O)C2CCOc3ccccc32)c1 +Cc1occc1C(=O)Nc1cccc(S(=O)(=O)N=C2CCCN2)c1 +CCn1cc(C(O)Cc2ccc(F)cc2Cl)cn1 +Cn1ccc(CNC(=O)NCC2CN3CCCCC3CO2)c1 +O=C(Nc1ccc2c(c1)CCC2)c1ccc2ccccc2n1 +COC1CCN(C(=O)c2ccc(-c3ccccc3F)s2)CC1 +Cn1cccc(NC(=O)CCOc2ccccc2-c2ccccc2)c1=O +O=C1NC(c2ccccn2)Nc2cc(Cl)ccc21 +CC1NC(=O)C2CN(C(=O)c3cccc(F)c3)CCN2C1=O +CC1=Nc2ncnn2C(c2ccncc2)C1C(N)=O +CCCCOc1cccc(CNC(=O)c2ccoc2)c1 +Cc1cc(SCC(=O)NC2CCCC2)nc(=O)[nH]1 +CCOc1ccc2c(c1)C(c1ccc(C)nc1)NCC2 +Cc1cccc(C)c1OC(C)(C)C(=O)N1CCNCC1 +Cc1nn(C)c(C)c1CC(C)C(=O)Nc1ccccc1C(=O)C(C)C +Cc1ccc(CNC(=O)NCC(C)Cn2cccn2)s1 +COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2C)cn1 +CCOC1C2CCC1N(C(=O)c1cnc(C)cn1)CCO2 +COc1cc(C)ccc1OCC(=O)Nc1cc(F)c(F)c(F)c1 +CN1Cc2cc(C(=O)c3ccccc3O)cnc2NC1=O +O=c1oc2ccccc2c2c1ncn2C1CCCCC1 +COc1ccc(OC)c(-n2nnnc2-c2ccc(C)c(N)c2)c1 +Cc1noc(C)c1COc1ccc(C2OCCCO2)cc1N +O=c1c2ccccc2ncn1-c1ccc2c(c1)OCCO2 +COc1nc2c(cc1C(=O)NCCn1cc(C)cn1)CCC2 +O=C(Nc1cccc(Cn2cccn2)c1)c1cccc2ncccc12 +Cn1cc(NC(=O)CNC(=O)CC(C)(C)C)ccc1=O +Cc1nc(-c2cccnc2)nc(N2CCC(O)C2)c1C +Cc1nc(-c2ncccn2)sc1C(=O)N(C)C(C)c1ccncc1 +CS(=O)(=O)NC1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1 +O=C(NCCO)C1CCCN1C(=O)c1ccccc1OC(F)F +CSc1ccc(CNC(=O)C2CC(=O)N(C(C)(C)C)C2)cc1 +COc1ccc(-c2n[nH]c(C3CC3)c2NC(C)=O)cc1 +Cc1ccc(OCC(=O)Nc2ccc(NCc3cccnc3)cc2)cc1 +CC(C)(C)CC(=O)NCC(=O)Nc1ccnn1C1CCCCC1 +CCCn1cc(S(=O)(=O)N2CCC3(CCCN(C)C3=O)C2)cn1 +CNC(=O)c1cncc(OC2CC2)c1Br +O=S(=O)(c1cccc(Cl)c1)N(CCO)C1CCCC1 +Cc1ccc(Oc2ccc(C(=O)N3CCC(C)CC3)cc2)nn1 +CC(=O)NCCNC(=O)c1cnc(N)c(Cl)c1 +O=C(NCc1ccc(OCC(F)(F)F)nc1)c1csnn1 +COc1ccc(Br)cc1NC(=O)NCCCO +Cc1ncc(COC(=O)c2cnn(-c3ccncc3)c2C)s1 +CC(NC(=O)c1ccc(C#N)cc1)(C(N)=O)c1cccc(Cl)c1 +O=C(NCCO)c1csc(-c2cccs2)n1 +Cc1nc(CSc2nnc(NCc3ccccc3)s2)cs1 +C=CCN(Cc1ccccc1)Cc1cnc2nc(C)cc(C)n12 +CCOC(=O)c1noc2ncnc(N3CCc4ccccc43)c12 +Cc1cnc(NC(=O)c2c[nH]c(=O)c(Cl)c2)s1 +Cc1cc(NC(=O)c2c(F)cccc2F)nn1C +CC(NC(=O)N1CCNC(=O)CC1)C(=O)N1CCCCC1 +CCCc1ncc(CN(C)Cc2nc3ccccc3[nH]2)cn1 +O=C(CCc1nc2ccccc2s1)Nn1cnc2ccccc21 +CC(=O)N1CCN(c2ccnc(C)n2)CC(COc2ccccc2)C1 +CN(CC1CCOC1)C(=O)Cc1ccc(F)c(F)c1 +CCCCN(C)C(=O)c1cc(C2CC2)nc(SC)c1C#N +COC(=O)c1ccc(NC(=O)Cn2cnc3c(cnn3C)c2=O)s1 +O=C(Nc1ncc(Cl)cc1Cl)c1ccccc1F +CCOc1ccccc1NCC(=O)N1CCN(S(C)(=O)=O)CC1 +COc1cccc(-c2nnn(CCOc3ccc(F)cc3)n2)c1 +Cn1cc(C2CN(Cc3nc(-c4ccccc4)cs3)CCO2)cn1 +Cc1noc(C)c1CCCNC(=O)C1COc2ccc(F)cc2C1 +CN(Cc1n[nH]c2c1CCC2)C(=O)c1cc(=O)n(C)c(=O)n1C +CCn1c(CNCc2ccc(OC)nc2)nc2ccccc21 +COC(=O)c1sc2ccccc2c1NC(=O)c1cc(C)n(C)n1 +Cc1cc(C(=O)N2CC(C(=O)NCCc3ccccc3)C2)no1 +Cc1nc2cc(NC(=O)c3ccc(Cn4cccn4)cc3)ccc2o1 +COc1cc(C)c(NC(=O)c2cccc(-n3cccc3)c2)cc1OC +COC(=O)c1cnn(-c2ccccc2Br)c1N +CCCCCn1nnc(S(=O)(=O)c2ccc(C)cc2)c1N +Cn1cnc(CNS(=O)(=O)c2cccc(-n3cnnn3)c2)n1 +Cc1ccc(-n2ncc3c2ncn2c(-c4ccccc4O)nnc32)cc1 +Cc1ccc(NC(=O)c2ccc(-c3cccs3)nc2N)nc1 +Cc1cc2c(cc1C)C(c1ccc(=O)[nH]c1)NCC2 +CCc1nc(COC(=O)CSc2ccc(F)cc2)cs1 +CN(C(=O)Cn1ncnc1-c1ccccc1Cl)c1ccccc1 +CCC(C)Nc1ncnc(-n2nc(C)cc2C)c1N +O=C(Nc1cccc(Cn2cccn2)c1)N1CCOCC1C1CC1 +CCn1cc(Cl)cc1C(=O)N(CCCO)C(C)C +O=C(NCCCN1CCCC1=O)NCc1cccc(O)c1 +O=C(NC1COc2ccccc2C1=O)c1cc(Br)c[nH]1 +CC(C)(C)c1ccc(O)c(NC(=O)c2ccc3nncn3c2)c1 +COc1cc(C2NCCc3c(Cl)cc(O)cc32)ccn1 +CCN(CC)c1nc(C)cc(C(=O)Nc2ncc(C)s2)n1 +O=C(Nc1ccc(C#CCO)cc1)c1c[nH]c(=O)[nH]1 +O=C(Nc1nc2ccccc2s1)c1n[nH]c2ccccc12 +O=C(Cc1ccc(Cl)cc1)NCC1(O)CCCC1 +Cc1ccncc1NC(=O)N1CCN(Cc2cccs2)CC1 +COC(=O)C1CN(CCc2ccc(OC)cc2)CCC1=O +COCC(C)(C)NC(=O)Nc1cccc(N2CCCCC2=O)c1 +COCCOCCNC(=O)c1ccn(C)c(=O)c1 +COc1ccc(CNC(=O)c2cc3ccccc3[nH]2)cc1OC +COc1cccc(COC(=O)c2ccc(N3CCCC3=O)cc2)c1 +O=C(Nc1ccc[nH]c1=O)C1CC(=O)N(c2cccc(Cl)c2)C1 +Cc1cccc(OCC(=O)OCc2ccccn2)c1 +N#Cc1ccc(-c2noc(-c3ccc4c(c3)OCO4)n2)nc1 +CCN(CC)C(=O)c1sc(NC(=O)C2CC2)c(C#N)c1C +COc1ccc(NC(=O)c2ccc(Cl)cc2Cl)cn1 +COC(=O)CSc1ncnc2c1nnn2-c1ccc(F)cc1 +CCOc1ccc(-n2ccc3c(nnc4nc(CC)nn43)c2=O)cc1 +Cc1cccc(OCC(=O)NCc2ccncc2)c1C +CNc1snc(C)c1C(=O)N(C)Cc1cc(C)on1 +CNC(=O)c1cnc(C=Cc2ccc(F)cc2)s1 +CC(C)N(Cc1ccccc1)C(=O)c1ccccc1N +Cc1nnc(NC(=O)C2CCCCN2S(C)(=O)=O)s1 +Cc1cc(C)cc(-n2nnc(CO)c2-c2cccs2)c1 +CC(C)COCCNC(=O)N1CCN(c2ncccc2F)CC1 +CCc1n[nH]c(SCc2nnnn2-c2cc(C)ccc2F)n1 +CCc1nn(-c2ccc(F)cc2)c(CC)c1C(=O)N1CCN(C)CC1 +CCOc1cc(CN2CCNC(=O)CC2)ccc1OC(F)F +COc1ccc(-c2nc3ccc(N)cc3o2)cc1Cl +O=C(Nc1ccc2c(c1)C(O)=Nc1cccnc1O2)C1CC1 +Cc1noc(CCC(=O)NCC(=O)N2CCCc3ccccc32)n1 +Cc1nnc(CN(C)C(=O)C(CC(C)C)N2CCCCC2=O)n1C +COc1ccc(C(C)=O)c(OCC(=O)N(C)Cc2ccc(F)cc2)c1 +CCN(Cc1cnn(C)c1)C(=O)NCc1ccccn1 +Cc1ccc(-c2nnn(CC(C#N)CCC#N)n2)cc1 +CCC(C)NS(=O)(=O)c1ccc(Br)cc1C +COc1coc(C(=O)Nc2ccc(Oc3ccccc3)cc2)cc1=O +CCC(=O)N(Cc1cccnc1)Cc1cc2cc(C)c(C)cc2[nH]c1=O +Cc1n[nH]c(C2CC3CCN(S(=O)(=O)c4ccccc4)CC3O2)n1 +CCc1nc(CN(Cc2ccc(OC)cc2)S(C)(=O)=O)cs1 +O=C(Nc1ccc(F)c(C(F)(F)F)c1)N1CCCC1CO +CCc1noc(Cn2cnc3sc4c(c3c2=O)CCCC4)n1 +Cc1ccc(NC(=O)CSc2n[nH]c(=O)n2C2CC2)cc1C +CCCn1c(C)cn2c3c(=O)n(CC)c(=O)n(C)c3nc12 +Nc1c(-c2ccccc2F)noc1C(=O)N1CCOCC1 +CC(CNC(=O)CCn1cc(S(N)(=O)=O)cn1)c1ccccc1 +CCOc1ncccc1C(=O)Nc1ccc(C(C)=O)cc1 +Cc1ccn2c(=O)c(C(=O)NC3(C)Cc4ccccc4C3)cnc2c1 +COc1cccc(Cn2nc(C)c(NC(=O)c3ccncc3)c2C)c1 +CC(C)C(C(=O)NCc1ccccn1)n1nnc(-c2ccccc2)n1 +O=C(NCCS(=O)(=O)c1ccccc1F)Nc1ccccc1 +Cc1c(Cl)cccc1S(=O)(=O)Nc1cnn(C)c1 +CN1C(=O)CCc2cc(NS(=O)(=O)Cc3ccc(F)cc3)ccc21 +Cc1cccc(NC(=O)N2CCN(Cc3nc(C)c(C)o3)CC2)n1 +N#Cc1cc(F)ccc1Cn1nnc(-c2ccsc2)n1 +CNC(=O)c1cccc(OC(=O)Cn2nc(C)c(Cl)c2C)c1 +CC1(C(=O)NCC2(O)CCC(C(C)(C)C)CC2)CCOCC1 +Cc1nc2cc(-c3ccccc3)sc2c(=O)n1N +COc1ccc(NC(=O)N2CCN(c3ccc(O)cc3)CC2)cn1 +CCOCc1ccccc1CNC(=O)NCC1CCC1 +CCc1onc(C)c1NC(=O)C1CCCN1C(=O)C1CC1 +CCn1cnnc1CNC(=O)C(C)NC(=O)c1ccco1 +Cc1csc(C(OC(=O)c2cnn(C(C)(C)C)c2)C(F)(F)F)n1 +CC(NCCc1ccccn1)c1ccc(F)c(Cl)c1 +C=CCN(C(=O)c1ccnc(OC2CCOC2)c1)c1ccccc1 +CCOC(=O)c1cn(CC)c2nc(C)ccc2c1=O +CCCc1ccccc1NC(=O)CN(C)S(C)(=O)=O +COC(=O)CC1CN(Cc2c(C3CC3)nc3sccn23)CCO1 +COC(=O)CNC(=O)NCCOc1cccc(Cl)c1 +Cc1cccc(C(=O)NC(C)C(=O)NCCCC2CCCC2)c1 +CC(=O)N(C)c1ccccc1NC(=O)C1CC=CC1 +COc1ccc(SC(C)C(=O)Nc2ccccc2O)cc1 +Cc1ccc(NC(=O)C(O)C(O)C(=O)Nc2ccc(C)cc2)cc1 +Cc1cn(S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)cn1 +CCC(C)(C)NC(=O)COc1ccc(C)cc1OC +O=C(NCC12CC3CC(CC(C3)C1)C2)c1ccncc1 +O=C(NCCn1ccnn1)c1ccc2cccc(F)c2n1 +Cc1cnc(NC(=O)c2c[nH]c3ccc(Br)cc23)s1 +CC(C)(C)OC(=O)N1CCCC(CNC(=O)c2cccs2)C1 +CCN(CCO)C(=O)c1cccc(OCc2ccccc2)c1 +Cc1ccc(C(=O)N(C)C)cc1OCC(=O)NCc1ccccc1F +C=CCN(Cc1cccc(C#N)c1)C(=O)c1ccnc2ccccc12 +Cc1ccc(NC(=O)NC(C)c2cccnc2)cc1OCC(F)F +CCc1nc(COc2nnc(-c3ccccc3)o2)cs1 +COc1cc2nc(-c3ccc(F)cc3F)oc(=O)c2cc1OC +CNC(=O)Cc1ccc(NC(=O)c2ccco2)cc1 +CC1CN(C(C)C(=O)N2CCSc3ccccc32)CC(C)O1 +O=C(NCCc1ccccc1)c1n[nH]c2c1CCCC2 +Nc1cc2c(c(COc3ccccc3)c1)OCOC2 +COc1ccc(-n2c(=O)[nH]c3c(c2=O)C(C)(C)Cc2ccccc2-3)cc1 +CC1CC(C)CN(C(=O)C(C)n2cc(Br)cn2)C1 +CC(NC(=O)NC(Cc1ccccc1)C1CC1)c1ccncc1 +CCOc1cc2c(cc1CNC(=O)C1CCC(=O)NC1)OC(C)C2 +CCCC12CN(C(=O)CC)CC(CCC)(CN(C(=O)CC)C1)C2=O +CCc1onc(C)c1NC(=O)CCCc1ccc2[nH]c(=O)[nH]c2c1 +CCNC(=O)C1(c2ccc3c(c2)OCO3)CCOCC1 +CCN(CC)C(=O)C(C#N)CCOc1ccccc1F +COC(=O)CN(C(=O)c1c(F)cccc1Cl)C(C)C +COCCN(CC(=O)OC)C(=O)c1sc2ccccc2c1Cl +N#CC(NC(=O)Cc1c[nH]c2ccccc12)c1cccs1 +Cc1ccnc(NC2CCC(Nc3nccc(C)n3)CC2)n1 +CCOc1ccc(CNC(=O)c2cnc(CC)nc2C)cc1OC +Cc1ccc2c(c1)SCC(=O)N2CC(=O)N(C)Cc1ccoc1 +COCCOc1cccc(C(=O)N(C)C2CCc3ccccc3C2)c1 +COC(C)(C)c1noc(C2CCN(C(=O)C(C)(C)C)CC2)n1 +Cc1c(C(=O)NC(c2ccc(Cl)cc2)C(F)(F)F)cnn1C +CCOC(=O)C(CC)n1c(=O)oc2ccc(CO)cc21 +N#CCCNc1cc(-c2ccc(F)cc2)nc(-c2ccccn2)n1 +CCSc1ccc(C(=O)CCC(=O)OC)cc1 +COc1ccccc1C(NCc1noc(C)n1)c1ccccc1Cl +N#CC1(NS(=O)(=O)c2cccc(Cl)c2)CCCC1 +O=C(Nc1cccc(CN2CCOCC2)c1)c1ccncc1F +CCCn1ccc2sc(C)c(C(=O)NC3CCCC3)c2c1=O +O=C(C1CCOC1)N1CCN(C2CCCC2O)CC1 +CCCCn1nc(-c2ccccc2OC)cc(C#N)c1=O +CC(=O)Nc1ccc(Nc2ccc3nnnn3n2)cc1 +Nc1ccc(F)c(S(=O)(=O)NC2CCCCC2O)c1 +Cc1cc(=O)c(C(=O)NCC(C)(C)c2ccccc2C)c[nH]1 +Cc1ccc(NC(=O)N2CCN(C)c3ncccc32)c(C)c1 +COC(=O)c1coc(C(CO)NC(=O)c2ccccc2)n1 +Cc1nc(CC(=O)NCCc2c[nH]c3ccc(Cl)cc23)cs1 +COCCN1CCN(C(=O)c2c(C)n[nH]c2C(C)C)CC1=O +CC(=O)N1CCCC(C(=O)Nc2cccc(CO)c2)C1 +Cc1nc(CN2CCN(CC(=O)N(C)c3ccccc3)CC2)cs1 +CN1C(=O)CC(NC(=O)c2csnn2)C1c1ccc(F)cc1 +CCC(OC)C(=O)Nc1ccccc1Br +CC(=O)Nc1cccc(NC(=O)c2sccc2C(C)C)c1C +CCOc1ccc(NC2=NCC(=O)N2Cc2cccs2)cc1 +COc1ccccc1NC(=O)CNc1ccc(NC(=O)C(C)C)cc1 +O=C(C1CCCO1)N1CCn2cnc(COCC3CC3)c2C1 +CCCn1nc(-c2ccc(OC)c(OC)c2)cc(N)c1=O +O=C(Nc1cc2c(cc1Cl)OCO2)c1cnn(-c2ccccc2)n1 +COc1ccc(Cl)cc1-n1nnnc1-c1cccc(N)c1 +COC(=O)Cn1cc(NC(=O)NC2CCCCC2)cn1 +CN(C(=O)COC(=O)c1ccc(N2CCOC2=O)cc1)C1CC1 +CCNS(=O)(=O)c1ccc(C(=O)OC2CCCCC2)cc1 +O=C(Cn1cnc2ccccc2c1=O)N1CCc2ncccc2C1 +COCCNc1nc(-c2cccs2)nc2ccccc12 +CCOCC12COCC1CN(C(=O)CCOc1ccccc1)C2 +COCCn1c(C)cc(C(=O)CN2CCC(N(C)C(C)=O)CC2)c1C +CC(C)C(=O)Nc1ccc(CNC(=O)Nc2cnn(C)c2)cc1 +COc1cccc(C(=O)NCCCN2CCCC2=O)c1F +CCCCc1ccc(N2CC(C(=O)Nc3ccccn3)CC2=O)cc1 +COC(=O)c1ccccc1C(=O)c1ccc2c(c1)NC(=O)CO2 +CCC(C)c1ccc(S(=O)(=O)NC2CC2)cc1 +Cc1nc(C)c(CC(=O)N(C)C(C)c2ccc(F)c(F)c2)c(=O)[nH]1 +CC(=O)N1CCN(C(=O)C2(c3cc(C)cc(C)c3)CCC2)CC1 +Cn1cc(CC(=O)Nc2ccc(-n3cnnn3)cc2)c2ccccc21 +O=C(NCCc1ccccc1)c1cc(-n2cnnn2)ccc1F +CCNC(=O)c1cc(=O)c2cc(Cl)cc(N)c2o1 +C#Cc1cccc(N(C)C(=O)Cc2c(C)nc3c(c2C)c(=O)[nH]n3C)c1 +N#Cc1ccc(S(=O)(=O)CCSc2cccc(F)c2)cc1 +CN(CCNC(=O)Cc1ccc(F)c(F)c1)C(=O)OC(C)(C)C +O=c1cc[nH]c(C2NCCc3c(O)cc(O)cc32)c1 +O=C(CCCOc1ccccc1Cl)Nc1ccc(O)cc1 +COCc1ccc(C(=O)NCC2CN3CCCCC3CO2)cc1 +O=C(c1cccc(-n2ccnn2)c1)N1CCc2ccc(Cl)cc2C1 +C=CCOC(=O)c1cccc(OCc2csc(C)n2)c1 +Cc1cc(C)c(NC(=O)c2ccc(=O)[nH]c2)c(Cl)c1 +CN(CC(=O)NCCCC(N)=O)C(=O)c1cccs1 +COC(CNC(=O)Cc1cn2ccsc2n1)c1cccc(Cl)c1 +Cc1ccc(C)c2sc(NC(=O)CNS(C)(=O)=O)nc12 +NC(=O)NCc1ccc(NC(=O)c2c[nH]c3cccc(F)c23)cc1 +CNC(=O)C(C)CN(C)C(=O)c1scnc1C1CC1 +CSc1n[nH]c2ncnc(N3CCOCC3)c12 +COc1ccc(C)cc1C(=O)NCCCC(=O)N(C)C +CCOc1ccc(C2=CCN(C(=O)C3CCOC3)CC2)cc1 +Cc1ccc2c(c1)SC(C(=O)N1CCCC1c1cc(C)on1)C2 +O=C(NCCc1cc(Cl)c2c(c1)OCCO2)c1ccccc1F +Cc1cnc(C(=O)N2CCC3C2CCC(=O)N3c2cccnc2)cn1 +COc1cc(NCc2cccc(OC)c2OC)ccc1NC(C)=O +CC(=O)NCCNC(=O)NCc1nc(C)c(C)o1 +Cc1cc(C(CO)Nc2ccc(F)cc2)c(C)s1 +CC(C)C(=O)NCCNC(=O)NCc1ccc(F)cc1 +Cc1cc(C(=O)N2CCCC(C(=O)Nc3ccccc3)C2)c(C)o1 +CCOC(=O)N1CCN(C(=O)Nc2c(C)noc2CC)CC1 +CC(Sc1ncccc1Cl)C(=O)NC(C)(C)C +Cc1noc(CCNC(=O)NC2CCCN(c3ncccn3)C2)n1 +CN(C)c1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1 +CNC(=O)c1ccsc1NC(=O)c1c(F)cccc1Cl +CCc1ccc(NC(=O)C(C)Sc2nnc(CO)n2C2CC2)cc1 +C=C(C)CN(CC)C(=O)C(C)Sc1ncnc2c1cnn2C +Cc1nc(-c2nc[nH]n2)sc1C(=O)OCc1ccc(C#N)cc1 +CCCN(CC1CCCCO1)C(=O)c1scnc1C1CC1 +Cc1ccn2c(=NC(=O)CCc3nc(-c4ccncc4)no3)[nH]nc2c1 +Cc1cc(Sc2ccccc2)ccc1NC(=O)C(C)NC(N)=O +CC(C)CNC(=O)NC1CCN(C(=O)c2ccoc2)CC1 +Cc1cccc(C(=O)Nc2ccccc2CC(N)=O)c1 +CC(=O)NCc1cccc(-c2cccc(CO)c2)c1 +CN(C)c1ncc2c(n1)CCCC2NC(=O)c1cn2ccsc2n1 +NC(=O)C1CN(Cc2ccc(F)c(C(F)(F)F)c2)CCO1 +O=C(Cc1ccc2ccccc2c1)Nc1ccncc1 +Cn1cc(C(N)=O)cc1C(=O)OCCNc1ncnc2ccccc12 +Cc1ccc(N2CCC(CNC(=O)OC(C)(C)C)C2)nn1 +O=C(Cc1cccc(F)c1)NCC(=O)N1CCCS1(=O)=O +CCc1cc(C)c(C(=O)N2CCC(C(N)=O)c3ccccc32)o1 +CCCCCn1nc(C2CC2)cc(C(F)(F)F)c1=O +CCOC(=O)CNS(=O)(=O)c1ccc(C#N)c(Cl)c1 +CC(C)C(OC(=O)CCN1CCCC1=O)c1ccc(F)c(F)c1 +O=C(c1ccncc1)N1CCC(Oc2ccccc2Cl)CC1 +Cc1cccc2sc(NC(=O)c3cnccn3)nc12 +COc1ccc(Cl)cc1NC(=O)c1cn2ccc(C)cc2n1 +O=C(CC1(O)CCCC1)NC(c1ccncc1)c1cc(F)ccc1F +Cc1nn(C)c(C)c1C(=O)NCc1cccc(O)c1 +O=C(NCc1cccc2cccnc12)c1ccccc1F +COc1ccc(CC(=O)N2CCC(=O)CC2)cc1F +CCc1c(C)nn(-c2ccc(C(C)O)cc2F)c1C +O=C(c1ccc(C(F)(F)F)cc1)N1CCN(C2CCCC2O)CC1 +Cc1cc(C)c(CNC(=O)c2cnc(-c3ccccc3)nc2)c(=O)[nH]1 +CC(C)(C)OC(=O)N1CCCC(C2CCC(CO)CC2)C1 +Cc1cccc2ncc(C(=O)NCc3cn4c(n3)SCC4)c(=O)n12 +Cc1ccc(C)c(S(=O)(=O)NCCNc2nc3ccccc3o2)c1 +N#Cc1nc(-c2cccnc2)oc1NCc1ccccc1Cl +COc1cc(F)c(NC(=O)NC2(C)Cc3ccccc3C2)cc1OC +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1c[nH]nc1-c1ccccc1 +CCCN(CC1CC1)C(=O)c1ccnc(OC2CCC2)c1 +CCc1ccc(C(=O)Nc2cc(C#N)ccc2Cl)o1 +CS(=O)(=O)c1nnc(Cc2ccccc2F)s1 +Cc1ccc2nc(COCC(=O)N3CC(c4cccnc4)C3)[nH]c2c1 +CC(C)(C)c1ccc(C(=O)NCCC(=O)NCc2ccncc2)cc1 +CCOC(=O)CN(C)Cc1ccc(F)cc1C#N +CC(NC(=O)NCC(=O)NC1CC1)c1ccc(C(C)(C)C)cc1 +CC(O)CNc1ccc(S(C)(=O)=O)cc1S(C)(=O)=O +COC(=O)Cn1c2ccc(F)cc2c2nc(C)sc21 +O=C(NCC#CCOc1ccc(F)cc1F)c1cc(C2CC2)on1 +Cn1ncc2c(=O)n(Cc3cc(Cl)c4c(c3)OCCO4)cnc21 +CCCC1CN(C(=O)CCc2n[nH]c(N)n2)CC1NS(C)(=O)=O +N#CCC1NCCc2ccc(F)c(Br)c21 +COc1cc(OC)cc(-c2cc(C(C)C)nc(C)n2)c1 +COc1c(C)cnc(CSc2nncn2C)c1C +Cn1cc(CCC(=O)Nc2ccc(OC(F)F)c(F)c2)cn1 +O=C1CC2(CCN(C(=O)c3ccnnc3)CC2)c2ccccc2N1 +COc1cccc(N2CC3(CCN(C(=O)C(C)C)C3)CC2=O)c1 +COC(=O)CC(O)C1CCN(C(=O)OC(C)(C)C)CC1 +COCC(C)NC(=O)COc1cccc2ccccc12 +Cc1cc2cc(NC(=O)CNC(=O)CC(C)(C)C)ccc2[nH]1 +CC(=O)c1ccc2c(c1)N(C(C)C)C(=O)C(C(C)C)O2 +C=C(C)Cn1c(SCC(C)O)nc2c1c(=O)[nH]c(=O)n2C +CC(C)N(C)S(=O)(=O)Nc1ccc(Cl)c(N)c1 +COc1c(Cl)cccc1NC(=O)NCCc1nccn1C(F)F +O=C(Nc1cccc(NC(=O)c2ccoc2)c1)c1ccc(F)nc1 +CCOc1ccccc1CNS(=O)(=O)c1cnc(N)nc1 +Cc1n[nH]c(C)c1S(=O)(=O)NCc1cnn(-c2ccccc2)c1 +COc1ccc(-c2nnc(COc3cc(C)c(C)nn3)o2)cc1 +CC(C)COCCNC(=O)Nc1ccc(N2CCCC2=O)cc1 +Cc1cc(CNS(=O)(=O)c2c(F)cccc2F)c(C)o1 +COCCN(Cc1ccco1)C(=O)CC1C=CCC1 +CCC(C)NC(=O)c1ccc(NC(=O)CCc2cnn(C)c2)cc1 +Cc1nnc(S(=O)(=O)CCc2ccccc2)n1CC(=O)N(C)C +O=C(NCc1cc[nH]n1)N1CCOCC1C1CC1 +CSc1ncc(Cl)c(C(=O)Nc2cc(C)on2)n1 +COc1ccc(NC(=O)c2cc(C)ccc2F)cc1S(N)(=O)=O +CC(=O)c1cccc(Nc2nc(C)c(CCO)c(=O)[nH]2)c1 +CCCNC(=O)CCn1c(-c2ccc(F)cc2)cc(C(C)=O)c1C +N#CCOc1cccc(CC(=O)N2CC(=O)Nc3ccccc32)c1 +Cc1cc(C(=O)N2CCC3(CC(N4CCCC4=O)CCO3)C2)c(C)o1 +C=CCn1nnc(NCc2ccc(Cl)c(Cl)c2)n1 +CCCCn1c(=O)[nH]c(=O)c2c1nc(COc1ccccc1F)n2C +C#CCN1CCN(C(=O)NCc2cccc(OCC(N)=O)c2)CC1 +CNC(=O)c1ccc(-c2ccc(Cl)c(Cl)c2)nc1N +Cc1cc(NC(=O)Cc2c(Cl)cccc2Cl)[nH]n1 +O=C(NCCOc1cccc2cccnc12)c1ccc2ncccc2n1 +CCn1ccc(C(=O)N(Cc2ccc(SC)cc2)C2CC2)n1 +CCn1c(CCC(N)=O)nnc1SCc1nc2ccccc2n1C +O=C(NCc1cnn(-c2ccccc2)c1)N1CCc2ccccc21 +Cc1nn(C(C)(C)C)cc1C(C)NC(=O)NCc1ccco1 +CC(C)CCNC(=O)Cn1nc(-c2cccs2)ccc1=O +CCc1ccc(NC(=O)c2nc(-n3ccnc3)ncc2Cl)cc1 +Cc1ccccc1NC(=O)c1cc2c(CO)cnc(C)c2oc1=O +CCOC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1ccco1 +COCCCNC(=O)CN1CCOc2ccccc21 +COc1cc(N)c(C(=O)NCC2CCC2)cc1OC +CCSc1cc(C(=O)Nc2cccc(C)c2)ccn1 +O=C(CC1C=CCC1)Nc1cc(N2CCCS2(=O)=O)ccc1F +CCN(CCOc1cccc(C)c1)C(=O)c1oc(C)nc1C +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NCc1ccco1 +COc1cccc(-c2n[nH]c(C)c2NC(=O)c2ccc(F)cc2F)c1 +Cc1nc(CN2CCN(C(=O)NCc3ccco3)CC2)cs1 +Cc1cc(C(N)C(F)(F)F)ccc1Br +Cc1cc(S(=O)(=O)Nc2ccccn2)c(C)cc1Cl +CN(CC(=O)Nc1cc(Cl)ccc1F)c1nccs1 +O=C1CCN(c2ccc3c(c2)OC(F)(F)O3)C1=O +CCS(=O)(=O)N1CCN(C(=O)Nc2ccc(F)cc2Cl)CC1 +NC(=O)CSc1ncnc2c1cnn2-c1ccc(Cl)cc1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccc(F)cc1Cl +CC(C)N(CC1CC1)C(=O)c1ccc(N)cc1Cl +Cc1cc2c(cc1C(O)c1cccs1)n(C)c(=O)n2C +O=C(Nc1ccc(Cl)cc1C(F)(F)F)c1ccncc1 +COc1ccc(OC)c(C2CCCN2C(=O)CCc2nc(C)no2)c1 +CC(NC(=O)c1ccc(S(=O)(=O)NC2CC2)cc1)c1cccnc1 +CCc1noc(C(C)N2CCCC(c3nncn3C(C)C)C2)n1 +O=C1CCC(C2NCCc3c2ccc(Cl)c3Cl)N1 +CSc1ccc(C(=O)N2CCOCC2c2noc(C(C)C)n2)cc1 +Cc1noc(C2CCC3(CCN(C(=O)c4ccc(C)s4)CC3)O2)n1 +Cn1cc(CC(=O)N2CCCN(c3cccnn3)CC2)c2ccccc21 +CC(C)(C)CN(CCC#N)S(=O)(=O)c1ccccc1F +CC(C)(C)n1cc(NC(=O)CCc2nc(-c3ccncc3)no2)cn1 +Cc1noc(C)c1CN(C)C(=O)Cc1cccc(OCC#N)c1 +CCOC(=O)C(C)NC(=O)C(C)NC(=O)c1cccs1 +CC(C)NC(=O)NCCN1CCN(Cc2cccs2)CC1 +NC(=O)C1CCN(C(=O)NCC2(c3ccccc3)CCOCC2)CC1 +COc1ccc(NC(C)=O)cc1Nc1ncnc2sccc12 +Cn1c(=O)ccn(CC(=O)Nc2cc(Cl)ccc2F)c1=O +Fc1cc(-c2nn3c(C4CC4)nnc3s2)cc(F)c1F +COC(=O)C(C)CN(C)C(=O)c1nc(C(C)C)ncc1Cl +CCN(Cc1ccc(C#N)cc1F)C(=O)Nc1cc(C)on1 +O=C1NCCN2CCN(C(=O)c3cc(-n4cnnn4)ccc3O)CC12 +COc1ccc(C(=O)c2ccc(N)cc2)cc1OC +Cc1cc(C)n(-c2cncc(NCC(O)c3cccc(F)c3)n2)n1 +CCCN1CCN(C(=O)C(C)NC(=O)c2ccoc2)CC1 +COc1ccc(C(=O)N2CCC(Oc3ccccc3)CC2)c(F)c1 +CCC(CC)NC(=O)Nc1cc(S(N)(=O)=O)cc(C)c1C +Oc1cccc(CN2CCCC(c3noc(-c4ccccn4)n3)C2)c1 +CCc1cccc(C)c1NC(=O)c1ccc(C)s1 +C=CCNC(=O)Cc1noc2c(C)c(C)c(N)cc12 +CCCn1nc(C(=O)N2CCc3ccccc3C2)c2ccccc2c1=O +Cc1ccc(NC(=O)c2scnc2C)cc1S(=O)(=O)N(C)C +Cc1ccc(S(=O)(=O)CCC(=O)NC(C)c2ccncc2)cc1 +CCCn1cc(NC(=O)CN(C)S(C)(=O)=O)ccc1=O +O=C(NCCCO)NCCc1csc(-c2ccccc2)n1 +CCc1nc(N2CCOCC2(C)C)sc1CO +COc1ccc(OCc2nc(-c3ccncc3)no2)cc1 +CCOC(=O)C1CC(=O)N(c2cccc(N)c2C)C1 +CCC(C)C(=O)N1CCCN(C(=O)Nc2ccc(Cl)cc2)CC1 +CCOC(=O)N1CCN(c2cccc3cc(C(=O)OC)[nH]c23)CC1 +NC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O +N#Cc1cc(O)c(-c2c(O)n[nH]c2-c2ccccc2)cc1C#N +O=C(CC1CN(Cc2ccccc2)CCO1)NCCc1cscn1 +Cc1oc(C(=O)N2CCOCC2C2CC2)cc1S(=O)(=O)N(C)C +CNC(=O)COC(=O)c1cc(-c2cccs2)n(-c2ccccc2)n1 +Nc1cccc2c1CCN(S(=O)(=O)c1ccc(Cl)cc1)C2 +COc1cnc(N2CCCN(c3ccc(F)cc3)CC2)nc1 +O=C1CCC(C(=O)N=c2[nH]c3ccccc3[nH]2)CN1 +CCOC(=O)NCc1cc(-c2ccccn2)n(C2CCCC2)n1 +O=C1CCCC2(CN(Cc3ccccc3)CC2c2ccncc2)N1 +CCC(C)NC(=O)c1cc(S(=O)(=O)N2CCOCC2)cs1 +CCOC(=O)C1CCCn2c1nc1sc3c(c1c2=O)CCCC3 +Cn1c(CNC(=O)NCC2CCCO2)nc2ccccc2c1=O +COc1ccc(-n2cccn2)c(-c2nccn2Cc2c(C)noc2C)c1 +CC1(C)C2CCC1(C(=O)Nc1cccc(C(F)(F)F)c1)C(=O)C2 +O=S(=O)(c1ccc2c(c1)CCO2)N1CCN2CCCC2C1 +COc1ccc(OC)c(CN(C)C(=O)c2cc(C)on2)c1 +O=C(CCCn1cncn1)Nc1ccccc1Oc1ccncc1 +COc1ccccc1NC(=O)c1cccc(NC(=O)c2ccco2)c1 +Cc1ccc2oc(C(=O)Nc3ccc(-c4ncc[nH]4)cc3)cc2n1 +Cc1cccc(CCCOC(=O)c2cn(C)nc2C(F)(F)F)n1 +Cc1ccnc(-c2ccc(NC(=O)N(C)C(C)CC#N)cc2)n1 +COC(C(=O)NC1CCCCC1OC)c1ccccc1 +Cc1sc(-c2noc(C3CC3)n2)cc1NC(=O)C1CCC1 +CN(CCC(F)(F)F)Cc1cnc(-c2ccccn2)s1 +Cc1ccc2c(c1)C(=O)C1CCCC1CS2(=O)=O +O=C(C1CCCN1C(=O)c1cc(Cl)cc(Cl)c1)N1CCC1 +Cc1ccc(F)cc1S(=O)(=O)N(CCCO)C(C)C +O=C(NCCNC(=O)c1cc(F)cc(F)c1)c1ccc(F)cc1 +COCCNC(=O)COC(=O)c1ccc(C)cc1 +CSc1ccc(C(=O)N(C)Cc2ccc(F)cc2F)cc1 +COc1cccc(NC(=O)C2(c3ccc(F)cc3F)CCOCC2)c1 +Cc1ccc(NC(=O)CCC(=O)N2CCCn3nc(C)cc32)c(C)c1 +CCNC(=O)COc1ccc(NC(=O)c2cccc(C)c2O)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccc(OC(C)C)nc1 +Cc1ccc(OCC(=O)Nc2c(C(N)=O)oc3ccccc23)c(C)c1 +O=C(CN1C(=O)CNc2ccccc21)N1CCc2ccccc2C1 +Cc1nccn1-c1ccc(NC(=O)Cc2ccc(F)cc2)cn1 +COc1ccc(NC(=O)CCC(=O)c2cccs2)c2cccnc12 +NC(=O)Cn1c(=O)nc(N)c2c3c(sc21)CCC3 +Cc1cccc(C)c1OCc1ncc(C(N)=O)c(N)n1 +COC(=O)C(Nc1ccccc1N(C)C)C(C)C +Cc1cc2nnc(-c3cccc(Br)c3)n2cc1N +CC1CCCC(NC(=O)C(NC(=O)Cc2ccccc2)C(C)C)C1 +CCN(Cc1ccccc1)C(=O)c1ccc(-n2nc(C)cc2C)cc1 +CCN(CC(C)O)C(=O)Nc1ccccc1C(F)(F)F +N#Cc1cnc(-c2ccc3c(c2)OCCCO3)cc1Cl +CCOC(=O)C1CCN(C(=O)c2cc(=O)[nH]c3ccccc23)CC1 +Cc1cccc(Cn2ccnc2CN(CC2CC2)C(=O)C(C)C)c1 +Cc1cc(C)n(-c2ncnc(N(C)c3ccccc3)c2N)n1 +CCN(Cc1cccs1)C(=O)Cc1c(C)nc(C)[nH]c1=O +COCC(C)NC(=O)Nc1ccc2c(c1)COC2 +CCc1nnc(NC(=O)NCc2ccc(Cl)cc2Cl)s1 +Cc1n[nH]c(SC(C)C(=O)Nc2ccc3c(c2)OCCO3)n1 +CCC1(CC)Oc2ccc(N)cc2N(CCC#N)C1=O +CCc1ccc(C(=O)NCCNc2cc(-n3cccn3)ncn2)cc1 +COc1ccc(CCNC2(C#N)CCCCC2)cc1OC +CCc1cccc(C)c1NC(=O)CN(C)C(=O)c1cccs1 +Cc1cc(Oc2ncccn2)ccc1NS(=O)(=O)c1ccccc1 +COc1cc(NC(=O)COc2ccccc2OC)cc(OC)c1 +CC(C)N(CCCO)C(=O)c1cc(Cl)cc(Cl)c1 +COC(=O)CC1CN(CC(C)(C)CCC#N)CCO1 +CCC(C)NC(=O)COc1ccc(C(C)=O)cc1OC +CCc1cc(NC(=O)c2cnn(-c3ccc(F)cc3)c2CC)[nH]n1 +Cc1ccc(SCC(=O)NC2CCC(=O)N(C)C2)cc1 +CN(C)c1ccc(C(=O)N2CCN(C(=O)C3CCCO3)CC2)cc1 +Cc1ccc2c(c1)OCC(=O)N2CC(=O)N1CCC(C)CC1 +N#CCn1cccc(OCc2ccccc2F)c1=O +COC1CCCCC1NC(=O)N1CCC(C(O)C(F)(F)F)CC1 +CCC(C)NC(=O)c1ccc(N2CCNC2=O)c(C)c1 +CN1CC(NC(=O)CCOc2ccc(Cl)cc2)CC1=O +CNC(=O)c1ccccc1NC(=O)c1ccccc1C +Cc1ccccc1C(=O)NC(C(=O)NCCCO)C(C)C +CC(C)(C)N1CC(C(=O)N2CCN(c3ccccc3F)CC2)CC1=O +Cc1cc(C(=O)Nc2ccc3c(c2)OCC(=O)N3)no1 +Cc1ccc(-n2cc(C(=O)N3CCc4sccc4C3)nn2)cc1 +Cc1nn(-c2ccc(C(=O)NCCCO)cc2)c(C)c1Cl +O=C(Nc1c(F)cccc1F)c1ccc(F)c(F)c1 +Cc1nc(C2CCCN(C(=O)c3cc(C(N)=O)cs3)C2)no1 +O=C(NCC1CCCO1)C1CCN(c2nc3cccnc3s2)CC1 +CCOC(=O)c1c(NC(=O)Cc2ccccc2)sc2c1CCC2 +Cc1ccccc1C(=O)Oc1cccc(-n2cnnn2)c1 +Cc1cccc(NC(=O)C2CCCN2C(=O)C2CC2)c1 +NC(=O)C1(CNC(=O)c2cc3ccccc3cc2O)CCOCC1 +CN(Cc1nc(N)c2ccccc2n1)Cc1nc2ccccc2s1 +CSc1ccc(CNC(=O)COc2ccccc2C)cc1 +Cn1c(C(=O)NCc2cccnc2)nc2c1CCN(c1ncccn1)C2 +COc1ccc(COC(=O)c2cc(C)n(C3CC3)c2C)cc1F +Cn1ncnc1CNC(=O)c1scnc1C1CC1 +O=c1ccc(-c2nnco2)cn1Cc1nc2ccccc2s1 +Cc1ccsc1C(=O)NC(C)C(=O)NCc1ccco1 +CCCNC(=O)CNc1ccc(C(=O)N(C)c2ccccc2)cc1 +CCC(C)N(CCOC)C(=O)c1cc(N)ccc1F +N#CC(C(=O)C1CCCCC1)c1ccc(C(F)(F)F)cn1 +CCOC1CC2(CCN(C(=O)c3cccnc3)CC2)C1 +Cc1cc(C#N)nn1Cc1ccc2c(c1)OCCO2 +CCN1C(=O)CCC12CCCN(C(=O)c1ccc[nH]1)C2 +CC(C)c1cccc(OCC(O)COC2CCOCC2)c1 +O=C(NCCc1cccs1)c1cc2ccccc2oc1=O +COc1cccc(CC2CCCN2c2ncnc3c2cnn3C)c1 +COc1ccc(CC(=O)Nc2ccc(F)c(N)c2)cc1 +CC(C)N(C(=O)c1cc2ccccc2oc1=O)C(C)C +Cc1ccc(CC(C)NC(=O)CCc2ccncc2)c(C)c1 +O=C(Cn1ccc2sccc2c1=O)NCc1ccccc1Cl +Cc1ncc(S(C)(=O)=O)c(NCCc2ccnn2C)n1 +Fc1ccc(C=CCNc2cnn(CC(F)F)c2)cc1 +COc1cc(OC)cc(C(N)c2nc(C)c(C)s2)c1 +O=C(NCCc1ccco1)C1CCN(c2ccc(F)cc2)C1=O +Cc1ccc(C)c(NC(=O)c2nn(-c3ccccc3)nc2C)c1 +COc1cc(NC(=O)c2cc(Cl)c[nH]2)ccc1NS(C)(=O)=O +CCOc1ccc(C(C)NS(=O)(=O)c2cccs2)cc1 +CC(C)Oc1ccc(-n2ccnc2SCCC#N)cc1 +COc1ccc(CCOc2ccc(F)cc2)cc1C(N)=O +CSc1cccc(NC(=O)C2CC(=O)N(C3CCOCC3)C2)c1 +CC(=O)c1cnn(-c2cc(C(F)(F)F)cc(C)n2)c1C +CCn1nc(C)c(CN(C)S(=O)(=O)c2c(C)noc2C)c1C +CCOc1ccc(-n2ccc3c(nnc4ncnn43)c2=O)cc1 +CN(CCc1ccncc1)C(=O)c1ccc(OCC2CC2)cc1 +CCNC(=O)c1ccc(NC(=O)N(C)Cc2ccoc2C)c(C)c1 +CN(C)c1ccc(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)cc1 +O=C(C1COc2ccccc2O1)N1CCC(O)(CO)CC1 +O=C(NC1CC1)c1ccnc(N2CC3C4CCC(O4)C3C2)c1 +Cc1noc(COc2ccc(NC(=O)C3CC4C=CC3C4)cc2)n1 +COCC(NC(=O)c1ccc(F)cc1C(F)(F)F)C(N)=O +Cc1nnc2n1CCN(C(=O)c1cc3ccccc3n1CC#N)C2 +CCCCn1nc(C#N)cc1-c1ccc2c(c1)OCCO2 +CCOc1cccc2sc(-n3nc(C)cc3N)nc12 +NC(=O)c1ccccc1NCc1nc(C2CC2)no1 +N#CCC(=O)Nc1ccc(C(=O)NCc2cccs2)cc1 +Cc1nc(-c2cccs2)sc1C(=O)OCCNc1cccnn1 +O=C(NCCC(=O)N1CCCc2ccccc21)c1cnn2ncccc12 +Nc1ccc(F)c2ccnc(C(=O)Nc3ccncc3)c12 +COCC(C)NC(=O)N1CCC(NC(=O)Nc2ccc(F)cc2)C1 +Cc1cc(C)n(CC(=O)NCc2ccc(F)cc2)c(=O)c1C#N +CCCCNC(=O)C1CC(=O)N(Cc2ccco2)C1 +Cc1cnc(C(=O)NCCNc2ncccn2)cn1 +COc1cccc(CNC(=O)Nc2ccc3c(c2)COC3)c1OC +COc1cccc(C(=O)N2CCN(CCC(N)=O)CC2)c1 +O=C1CCC(C(=O)NCCNC(=O)c2ccc(C(F)(F)F)cc2)N1 +COc1cc(C(C)Nc2ccc(F)cc2F)ccc1O +Cc1c(N)c2c(c(C)c1Cl)NC(=O)C(C(C)C)O2 +COc1ccc(COCC(=O)Nc2nc(C)c(C)s2)cc1 +COc1ccccc1NC(=O)NCCc1nc(C)no1 +CC(C)Oc1c(Cl)cccc1NC(=O)N1CC(c2ccccn2)C1 +CNc1nc2c(s1)C(c1cccc(F)c1F)CC(O)=N2 +CC(=O)NCC(=O)Nc1ccc(Cl)c(OC(F)F)c1 +CC(=O)c1cccc(S(=O)(=O)NCCc2ccoc2)c1 +c1cnnc(N2CCCC(NCc3nnnn3C3CC3)C2)c1 +COc1cccc(-c2cc(C(=O)N(C)Cc3snnc3C)[nH]n2)c1 +Cc1c(N)c[nH]c(=O)c1C(=O)NCc1ccncc1 +CCSc1ncc(S(=O)(=O)c2ccccc2)c(N)n1 +CN(Cc1ccccn1)C(=O)Nc1ccc(CC#N)cc1 +CCC(=O)Nc1ccc(O)c(C(=O)Nc2ccc(CC#N)cc2)c1 +CC(C)(C)OC(=O)NCCC(=O)NCc1ccccc1 +CSc1nc2ccc(NC(=O)c3cnn(C)c3)cc2s1 +COc1ccc(N2CCN(C(=O)c3cnc(C)cn3)C(C)C2=O)cc1 +Cc1cc(S(=O)(=O)NCCCO)c(C)cc1Cl +OCc1cc(Cl)ccc1OCCc1cccnc1 +O=C(C1CC1c1ccc(C(F)(F)F)cc1)N1CCOCC1C1CC1 +CCCN(C(=O)C1CCCO1)C(c1ccc(F)cc1)c1cccnc1 +CC(C)c1nnc(NC(=O)CNc2cccc(F)c2)s1 +COCCOC(=O)C1=C(C)Nc2ncnn2C1c1ccccc1F +OC(COc1ccccc1)Cn1c(C(F)F)nc2ccccc21 +Cn1nccc1CNS(=O)(=O)c1ccc2c(c1)CCO2 +COc1cccc(C(=O)OC(C)c2nc(C)no2)c1 +COc1ccccc1N1CCN(C(=O)C2CC3C=CC2C3)CC1 +CCN(C(=O)CSc1nncn1C(C)C)c1ccccc1 +Cn1nc2n(c1=O)CCN(CCOc1ccc3ccccc3c1)C2 +CN(C)S(=O)(=O)c1ccc(CCC(=O)N2CCCCC2)cc1 +Cc1ccc(NCc2nnc3n(C)c(=O)c4ccccc4n23)cc1F +COc1ccccc1C(=O)NCCc1nc(C)cc(C(F)(F)F)n1 +CCOc1ccccc1CNC(=O)c1cn[nH]c1-c1cccs1 +CN(c1ccccn1)S(=O)(=O)c1ccc2c(c1)CCCC(=O)N2 +COCCN(Cc1c(C)nc2sc(C)cn12)CC(F)F +Nc1cc(N2CCN(C(=O)C3CCC3)CC2)ccc1Cl +O=C(OCc1cc(-c2ccc3c(c2)OCO3)on1)c1ccno1 +C#Cc1cccc(N(CC(=O)NC)Cc2ccc(C(N)=O)cc2)c1 +Cc1ccc(C2COCCN2C(=O)NC2CCOc3ccccc32)o1 +O=C1Nc2ccc(CNS(=O)(=O)c3ccccc3)c3cccc1c23 +C=CCN(Cc1cccc(OC)c1OC)C(=O)N(C)C +Nc1c(C(=O)N2CCCC2)nsc1C(=O)NCc1cccs1 +Cc1noc(C)c1CC(=O)N1CC(c2nc(-c3ccccn3)no2)C1 +Cc1nnc(S(=O)(=O)CC2CCCO2)n1Cc1ccccc1 +CNC(=O)c1ccc(S(=O)(=O)NC(C)(CC(C)C)C(N)=O)cc1 +CCOC(=O)C(C)(C)NCc1nc(-c2ccco2)no1 +C=CCn1cnnc1SCC(=O)c1c[nH]c2ccccc12 +CCN(C(=O)Cn1ccc(=O)n(C)c1=O)C12CC3CC(CC(C3)C1)C2 +CC1CCCN(S(=O)(=O)c2ccc(NC(=O)C(C)C)cc2)C1 +Cc1nccn1-c1ccc(C(C)NC(=O)NCc2ccnn2C)cc1 +CC(NC(=O)OC(C)(C)C)C(=O)N(C)Cc1ccco1 +O=c1cc(C2CCC2)ncn1CCc1ccccn1 +O=c1n(Cc2cc(F)ccc2F)nc2c(N3CCOCC3)nccn12 +CNC(=O)COc1ccccc1CNc1cc(C)cc(C)c1 +CCOCCCC(=O)NC1(c2ccc(Cl)cc2)CC1 +CC(C)c1ccccc1NC(=O)C(C)N1CCn2c(nn(C)c2=O)C1 +CNC(=O)CN(C)C(=O)c1cc(Cl)ccc1O +CCc1ncc(C(=O)NCCc2cccc(Cl)c2Cl)cn1 +NC(=O)c1cc(NC(=O)c2cccs2)c(Cl)cc1Cl +COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2cc(C)oc2C)c1 +Cc1cc(=O)c(OCc2ccccc2)cn1CC(=O)Nc1ccccn1 +CN(C)C(=O)c1cccc(NC(=O)CNc2cc(F)ccc2Cl)c1 +CN(C(=O)CC1OCCc2ccsc21)c1nc2ccccc2s1 +Cc1ccc(SCCn2c(=O)oc3cccnc32)cc1 +COc1ccccc1C(=O)CNc1c(C)cccc1C(C)C +COc1ccc(-c2cc(-c3nc(-c4ccc(C#N)cn4)no3)[nH]n2)cc1 +C=CCn1nnc(NCc2ccc(-c3ccc(OC)c(Cl)c3)o2)n1 +CCCCC(=O)N1CCC2(CC1)CN(Cc1ccccc1)C2=O +Nc1cc(Cl)cc2c(C(=O)Nc3ccccn3)nccc12 +c1cc2ccc(NCCSc3cnn[nH]3)nc2[nH]1 +Cc1ccc(OCC(=O)Nc2cc(N)ccc2C)c(C)c1 +CC(C)CNc1nc(C(=O)NCCc2ccccn2)cs1 +CCOC(=O)c1[nH]c(C)c(C(=O)Nc2ccccc2OC)c1C +CCOC(=O)Cc1csc(NC(=O)C(C)CC)n1 +Cc1ccc(C(C)NC(=O)c2cnc(C3CCCO3)s2)cc1F +Nc1ccc(Cl)cc1-c1nnc(N2CCCC2)o1 +O=C(Cc1ccccc1)NCCc1nc(-c2ccccc2)no1 +CCCCN(C)c1nc(C(=O)OCC)nc2onc(C)c12 +O=C1CCC(NC(=O)Cc2c(Cl)cccc2Cl)CN1 +Cc1nc(C(=O)NCc2ccc(OC(F)(F)F)cc2)c(C)o1 +CCn1ccc(C(=O)N2CCC(c3nc4cccnc4n3CC)C2)n1 +C=CCN(CC=C)S(=O)(=O)c1c(F)cccc1F +CCn1c2cc(C)oc2c2cnn(CC(=O)NC3CCCC3)c(=O)c21 +Nc1nc(-c2cccs2)ccc1C(=O)Nc1nccs1 +COc1ccc(C2CC(c3ccccc3Cl)n3nnnc3N2)cc1 +Cc1ccc(C(NC(=O)NCc2cc[nH]n2)c2cccs2)cc1 +CC1CC(c2ccccc2)n2ncnc2N1C(=O)COc1ccccc1 +O=C(NCc1nc2ccccc2[nH]1)c1cc(-c2ccc(F)cc2)c[nH]1 +O=C(Cn1cnc2ccccc21)Nc1ccc(OC(F)(F)F)cc1 +CCOC(=O)c1sc(CCOC)nc1C(F)(F)F +NC(=O)c1ccccc1NC(=O)CCS(=O)(=O)N1CCNCC1 +O=C(NCCCO)Nc1ccc(Oc2cccc(F)c2)cc1 +Cc1nc(-c2cccc(NC(=O)c3cnn(C)c3)c2)cs1 +COC(=O)N1CCC(NC(=O)NC2CCc3cc(F)ccc32)CC1 +O=c1[nH]ccn(-c2cccc(C(F)(F)F)c2)c1=O +Cc1ccc2c(c1)N(C(=O)CCC(=O)NCc1ccco1)CC(C)O2 +Cc1cc(CN2CCOC(c3cccc(O)c3)C2)ccc1F +O=C(N=c1[nH]c2ccccc2[nH]1)c1ccncc1Cl +N#CCCCOc1ccccc1C(=O)Nc1ccccc1 +N#CCCNS(=O)(=O)c1ccc(Br)cc1 +O=C(COc1ccccn1)Nc1ccc(Cl)c(C(F)(F)F)c1 +CCc1cccc(OC(=O)C(NC(=O)c2ccco2)C(C)C)c1 +O=C(NCc1ccc(-n2ccnc2)nc1)C1Cc2ccccc2O1 +O=C(COCC1CCCO1)N(Cc1cccnc1)c1ccc(F)cc1 +CC(C)(C)C(=O)Nc1cccc(NCC(=O)NC2CC2)c1 +c1ccc(Cc2nc(CNc3cc(C4CC4)ncn3)no2)cc1 +CCc1ncc(C(=O)Nc2cccc(C)n2)c(N)n1 +Cc1csc(C(O)(CC(=O)Nc2c[nH]ccc2=O)C(F)(F)F)n1 +Cc1ccc(S(=O)(=O)C(C)C(=O)Nc2cccc(C)c2C)cc1 +Fc1cccc(-c2nc(CN3CCOC(Cn4cccn4)C3)co2)c1 +Cc1nsc(NC(=O)N2CCN(C3CCCC3)C(=O)C2)n1 +COc1ccccc1NC(=O)CSc1nncn1Cc1ccco1 +Cc1[nH]c(=O)[nH]c(=O)c1Cc1nc(C2CCOC2)no1 +COc1ccnc(N2CCN(C(=O)c3c[nH]c(=O)c(Cl)c3)CC2)n1 +Cc1ccccc1C(=O)N1CCC(C(=O)N(C)C)CC1 +O=C(c1scc2c1OCCO2)N1CC2CC=CCC2C1 +CCOC(=O)C1(C)Oc2cccnc2N(CC)C1=O +CNC(=O)c1cc(Cl)ccc1NCC(=O)N1C(C)CCCC1C +COC(=O)CC(NC(=O)c1scnc1C)c1ccc(OC)cc1 +Cc1ccc(C(=O)N2CCc3[nH]cnc3C23CCCC3)c(C)c1 +CN(C)c1nnnn1Cc1ccc(Cl)cc1Cl +O=c1cc(CO)oc(CN2CCc3ccccc3C2)c1O +N#Cc1ccc(F)c(CNc2sccc2C#N)c1 +Fc1ccc(Oc2ccccc2)c(NCc2nnc(C3CC3)o2)c1 +O=C(NCc1cc(F)ccc1F)Nc1cccnc1-n1cncn1 +O=C(COc1ccccc1)NCCCn1ccnc1 +CCC1CCCC(NC(=O)NC(CC)COC)C1 +NC(=O)Cc1ccccc1NC(=O)c1cccc(Br)c1 +CC1CCN(C(=O)c2ccc(N3CCCCS3(=O)=O)cc2)CC1 +COc1ccc2nc(Cc3coc(-c4cccs4)n3)[nH]c(=O)c2c1 +O=C(Cn1c2c(sc1=O)CCCCC2)NCc1ccccc1F +CCN(Cc1ccc2ccccc2n1)C(=O)Cc1cc(C)on1 +CC1CCCCC1NC(=O)NCc1cnn(Cc2ccccc2)c1 +COc1ccc(OC)c(Cn2cnc3ccccc3c2=O)c1 +O=C(CC1CCCC1)NCc1nnnn1C1CCCCC1 +CCOCC(=O)N(C)c1cc(Cl)ccc1OC +Cc1cc(Cl)ccc1OC(C)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +COc1ccc(CNC(=O)CN(C)S(=O)(=O)c2ccccc2)cc1 +CC(NC(=O)c1ccc(-n2cncn2)nc1)c1ccc2c(c1)CCCC2 +O=C(NCc1csc(C2CC2)n1)NCC1CCCO1 +C=CCOc1c(N)cc(-c2nc(C)cs2)cc1OC +CC(=O)Nc1ccc(OCc2cnc(C)s2)cc1 +NC(=O)CC1CCN(C(=O)CCc2ccc(-c3ccccc3)[nH]2)CC1 +CCN1CC(C(=O)N2CCC(C)CC2C)CC1=O +CCCCNC(=O)NC(C)c1ccc(-n2cccc2)cc1 +CCOc1cccc2cc(-c3nnc(NC(=O)c4ccco4)o3)oc12 +COc1ccc(OC)c2c(C3CC3)cc(C#N)nc12 +CCC(NC(=O)c1scnc1C1CC1)c1c(C)noc1C +CCc1nnc2c(NC(=O)Cc3cccs3)cccn12 +COC(=O)c1ccc(F)c(S(=O)(=O)NCc2ccccn2)c1 +CCNc1ccnc(NCCNS(C)(=O)=O)n1 +Cc1oc(C)c(C(=O)NCCCn2cccn2)c1C +Cc1nnc(NC(=O)Cn2nc3c(cc2=O)CCCC3)s1 +CCOC(=O)c1c(C)oc2nc(C)nc(NCc3ccc(C)o3)c12 +COc1ccc(C)cc1N1CC(C(=O)N2CC(C)CC(C)C2)CC1=O +Cc1ccc(-n2nnc(C(=O)Nc3cc(F)cc(F)c3)c2C)cc1 +Cc1ccc2c(CC(=O)N3CCC(C(N)=O)c4ccccc43)c[nH]c2c1 +CCCc1noc(C(C)NC(=O)c2c(-c3ccccc3)noc2C)n1 +FC(F)(F)c1ccnc(NCc2ccc3c(c2)OCCO3)n1 +O=C(c1cnccn1)N1CCN(CCOc2ccccc2Cl)CC1 +Cc1cn(CC(=O)N2CC(n3cc(C(N)=O)nn3)C2)c2ccccc12 +Cc1ccc(-c2nnc3sc(-c4cnccn4)nn23)cc1 +CC1CCN(C(=O)CCNS(=O)(=O)c2cccnc2)CC1 +O=C(Cc1ccc(F)c(F)c1)NCc1csc(=O)[nH]1 +COCc1cc(N)nc(-c2ccc(F)c(Cl)c2)n1 +Cn1c(Oc2ccc(Cl)cc2Cl)nc(C#N)c1C#N +CC(=O)N1CCc2cc(C(=O)Nc3ccc(F)cc3)ccc21 +Cn1cnc2cc(OC(=O)c3c(F)cccc3F)ccc21 +CN(C)c1cc(-c2cnn(CC(=O)Nc3cnn(C)n3)c2)ncn1 +COCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 +CCn1nc(-c2nn3c(-c4cc(F)ccc4F)nnc3s2)cc1C +Cc1ccc(CCNC(=O)CNC(=O)c2ccoc2C)c(C)c1 +CC(c1c(F)cccc1F)N(C)c1ncnc2c1cnn2C +Cc1cc(OCCC(=O)N2CCNCC2)ccc1Cl +CC(CNC(=O)C1CC(=O)N(CC(F)(F)F)C1)Oc1ccccc1 +O=S(CCSc1ccc2ccccc2n1)c1ccccc1 +CCOc1cccc(Cn2cnc3ccccc32)n1 +COc1cccc(N2CC(C(=O)n3ccnc3)CC2=O)c1 +CCNC(=O)NC1(C(=O)NCC2CC=CCC2)CCCC1 +O=C(NCCCOCC1CC1)c1cc(F)cc2[nH]cnc12 +Cc1cc(C(=O)Nc2ccccc2CN2CCc3ccccc32)on1 +CC(=O)NC(C)C(=O)N=c1[nH]nc(-c2ccc(C)cc2)[nH]1 +Cc1cc2ncn(CC(=O)N3CCOCC3)c2cc1C +CC(c1nc2c(s1)CCCC2)n1cc(-c2ccc(CO)o2)nn1 +CC(NC(=O)OC(C)(C)C)c1cccc(S(=O)(=O)N(C)C)c1 +Cc1ccc(-c2cc(CNC(=O)NC3CCC(O)CC3)on2)cc1 +CCOC(=O)c1snnc1-c1ccc(OC)c(OC)c1 +CCCc1ccc(NC(=O)Cn2cnc(N)n2)cc1 +COc1cc(Br)ccc1NC(=O)c1ccncc1 +CCc1c(C)sc2ncn(Cc3ccccc3C#N)c(=O)c12 +COC(=O)Nc1ccc(NC(=O)NCc2cc(Cl)ccn2)cc1 +O=C1NCCN1C1CCCN(c2ccc3ccc(F)cc3n2)C1 +CC(C)(C)NS(=O)(=O)c1cc(N)c2c(c1)CC(=O)N2 +CCOC(=O)c1c(C)oc2ncn(CCc3ccccn3)c(=O)c12 +Cc1ccc(NC(=O)CCC2CC2)cc1N1CCCS1(=O)=O +O=C1Nc2cccc(Br)c2C1NC1CC1 +CCC(=O)N1CCC(NC(=O)NC(C)c2cccc(C#N)c2)C1 +CC(=O)Nc1nc(C(=O)NCc2nc(C)cs2)cs1 +O=C(NCC1(c2ccccc2F)CC1)N1CCCC1 +Cc1cc2c(=O)n(CC(=O)N(C)C3CCCCC3)cnc2s1 +CSc1ccc(-c2csc3nc(N)nn23)cc1 +N#CC(CC(=O)NCc1cccnc1)c1cccc(F)c1 +Cc1nc2ccc(NC(=O)Nc3ccncc3)cc2s1 +Cc1n[nH]c(C2CCN(C(=O)c3ccco3)CC2)n1 +Cc1ccc(C(=O)NCC(=O)N2CCOCC2)s1 +COCCn1cc(C(=O)N2CCCC2c2ccncc2)c2ccccc21 +CC(=O)Nc1ccc(NC(=O)CNC(=O)c2cc(C)cc(C)c2)cc1 +COc1cc(NC(=O)c2ccc(C)cc2O)ccc1N1CCCC1=O +Cc1nnc(-c2ccccc2Br)nc1C#N +Cc1cc(F)c2c(c1)CCCN2Cc1nc(C)no1 +COc1ccc(C(C)(C)C)cc1CC(=O)NCCCO +Cc1ccc(CNC2(Cc3cc(CC(C)C)on3)COC2)o1 +O=C(NCC1(c2ccc(Cl)cc2)CCCC1)c1n[nH]c(=O)[nH]1 +CC(=O)NC1CCCN(C(=O)c2ccc(CN3CCCC3=O)cc2)C1 +C=CCN(CCO)S(=O)(=O)c1ccc(C)cc1C +CC(C)(C)NC(=O)CNC(=O)c1sccc1OC(F)F +O=C(COC(=O)c1ccco1)Nc1cc(Cl)cc(Cl)c1 +Brc1csc(-c2noc(CSc3ncn[nH]3)n2)c1 +COc1cc(-c2nc(-c3ccccc3)n[nH]2)ccc1O +COc1ccc(-c2ccc(=O)n(CC(=O)NCc3ccco3)n2)cc1 +Cc1noc(C)c1S(=O)(=O)NCC1CC=CCC1 +O=C(c1cccc(Oc2cnccn2)c1)N1CCCC(O)C1 +COc1ccc(CC(=O)Nc2ccc(CC(N)=O)cc2)cc1 +O=S(=O)(NCCCN1CCOCC1)c1ccc2ccccc2c1 +Cc1ncc(CNc2cccc(NS(C)(=O)=O)c2)s1 +O=C(C1CCCCC1)N1CC(c2nc(-c3cccnc3)no2)C1 +CCCNS(=O)(=O)c1ccc2cc(OC)ccc2c1 +CCC(C)NC(=O)CN1CC(C(N)=O)Oc2ccccc21 +Cc1nccn1-c1cncc(C2CCCN2C(=O)c2cccnc2)n1 +C=CCn1cc(CN2CCC(c3cccc(OC)c3OC)C2)c(C)n1 +CCN(CCO)C(=O)NCc1cccc(NC(=O)c2ccncc2)c1 +CN(Cc1cnn(C)c1)C(=O)CN1C(=O)CSc2ccccc21 +CCc1ccc(OCCN2C(=O)Cc3cc(N)ccc32)cc1 +OCc1sc(COc2ccc(F)cc2)nc1C1CC1 +CC(C)CN(C)C(=O)c1cc2sc(N(C)C)nc2s1 +Cc1cccc(NC(=O)CN(C)C(=O)C2COc3ccccc32)n1 +CCCNC(=O)CS(=O)(=O)c1ccccc1OC +CC(NC(=O)Cn1c(=O)[nH]c2ccccc21)c1ccc(F)c(F)c1 +CCc1nc2c(nc3ccc(Br)cn32)c(=O)[nH]1 +NC(=O)CSc1nnc(-c2ccc(Cl)cc2)n1N +CCC(NC(=O)C1COc2ccccc2O1)c1ccc(C)cc1C +CCCCN(C)C(=O)c1cc(C)nc2onc(C)c12 +N#CC(C(=O)C1CCCO1)c1nc2cc(C(F)(F)F)ccc2s1 +COc1cccc(CN(CC2CCCO2)C(=O)c2ccc(C)cn2)c1 +COCCOC(=O)c1cn(C)nc1-c1cccs1 +Cc1ccc2ncc(C(=O)N3CCCC(CCC(N)=O)C3)n2c1 +CNc1nc(-c2c(C3CC3)oc3c2CC(C)CC3)cs1 +O=C1c2ccccc2-c2nc3cc(-n4cnnn4)ccc3nc21 +CCN(C(=O)NC1CCC(O)CC1)C(C)c1cccc(O)c1 +O=C(CS(=O)(=O)c1ccccn1)N(Cc1ccccc1F)C1CC1 +Cc1ccc2c(CC(=O)N3CCCC3c3cnn(C)c3)coc2c1C +O=S(=O)(Nc1cccc(Cl)c1F)c1ccccc1 +Cc1noc(C(C)C)c1C(=O)Nc1ccn(Cc2ccccn2)n1 +Cc1ccc(-n2nnc(CO)c2C2CCCO2)c(C)c1 +CCCC(NC(=O)c1cccc(OC)c1)c1nnc2ccccn12 +Cc1cc(C(=O)NCCc2ccc(-n3cccn3)cc2)on1 +O=C(COC(=O)c1cccs1)Nc1ccc2c(c1)OCO2 +Cc1nn(C)c(C)c1Cc1nc(-c2ccncc2)no1 +CCN1CCN(S(=O)(=O)Cc2cccc(C)c2)CC1 +Cn1cc(C(=O)Nc2ccc(O)c(Cl)c2)ccc1=O +O=C(CN1CCc2ccccc21)N1CCN(Cc2ccccc2)CC1 +CC(=O)c1cccc(OCc2ccc(S(=O)(=O)C(F)F)cc2)c1 +Cc1csc(N2CCCN(C(=O)Cc3cccs3)CC2)n1 +Cc1cc(C)cc(OCCNC(=O)c2cccnc2-n2cncn2)c1 +COc1cc(NC(=O)Nc2ccccc2F)cc(OC)c1 +CN(C(=O)c1cccn(Cc2ccccc2F)c1=O)c1ccccc1 +CCCCc1nnc(NC(=O)c2cc3cc(F)ccc3[nH]2)s1 +COc1ccc(OC)c(C(C)(O)CN2CCc3ccccc32)c1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1cccc(C(F)(F)F)c1 +COCCN(C)C(=O)Nc1ccccc1OC(F)(F)F +Cc1ccc(N(CCC#N)C(=O)c2ccccc2)cc1C +COc1ncccc1NC(=O)N(C)C1CCCCCC1 +COC(=O)c1cc(F)ccc1Cn1ncc(Cl)c(Cl)c1=O +O=C(Cc1ccc(F)cc1F)OCCn1c(=O)oc2ccccc21 +CCCCC(=O)NCC1CCN(C(=O)OC)CC1 +CC(C)(C)NC(=O)c1c(F)cc(Br)cc1F +CCOC(=O)C1=C(N)Oc2[nH]nc(C)c2C1c1ccc(OC)cc1 +O=C(Cc1cc(Cl)c2c(c1)OCCO2)N1CCOCC1 +Cc1cc(NC(=O)NCC(C)(C)c2ccncc2)nn1C +Cc1ccc(NC(=O)COCCc2ccccc2)cc1S(C)(=O)=O +CCOC(=O)N1CCN(c2oc(-c3cccnc3)nc2C#N)CC1 +COCCNC(=O)c1ccccc1Oc1ccccc1 +CC(=O)NCC(c1ccccc1Cl)N1CCOCC1 +Cc1cnc(NC(=O)c2cc3c(nc4sccn43)s2)s1 +CN(Cc1ccco1)C(=O)c1ccnc(-n2ccnc2)c1 +OCC1OC(n2ccc3cncnc32)C(O)C1O +N#Cc1ccc(F)c(C2NCCc3c(F)cccc32)c1 +CCC(CC)NC(=O)c1cccc(NC(=O)C(C)C)c1 +Cc1cc(C)cc(C(=O)N2CC(S(=O)(=O)c3ccc(F)cc3)C2)c1 +Cc1cc(SCCNc2ccc(F)cc2)n(C)n1 +NC(=O)c1ccc(NC(=O)c2ccc3ccccc3c2)cc1 +O=C(CCCOc1cccnc1)NCC1CN2CCCCC2CO1 +CC(=O)NC(C(=O)OCC(=O)N1CCc2ccccc21)C(C)C +CCN(Cc1cccs1)C(=O)c1ccc(Cl)cc1 +CNC(=O)N1CCC(Nc2ccccc2OC)CC1 +O=C(NCCN1CCN(c2ncccn2)CC1)c1ccco1 +CC1CCN(c2nc3ncc4c(c3c(=O)[nH]2)CCC4=O)CC1 +Cc1noc(C)c1CC(=O)NCc1cc(C(C)C)no1 +CCN1C(=O)C(C)(C)c2cc(S(=O)(=O)NCCCO)cc(C)c21 +CC(C(=O)N1CCCN(Cc2nccn2C)CC1)N1CCCCC1=O +COc1cc(C)nc(N2CCN(C(=O)c3ccn(C)c(=O)c3)CC2)n1 +CCCCS(=O)(=O)NC(C#N)c1ccccn1 +Nc1nc(COC(=O)c2ccco2)nc(Nc2ccc(Cl)cc2)n1 +O=C1CNc2cc(F)c(F)cc2N1Cc1ccc(Cl)cc1 +CC(C)NC(=O)CNC(=O)C1CCCCN1S(C)(=O)=O +O=S(=O)(NCCc1ccsc1)c1c(F)cccc1F +COCc1cccc(CNC(=O)NCc2ncn(C)n2)c1 +COc1ccc(C2CCCN2C(=O)c2ccoc2)c(OC)c1 +COc1cccc(-c2nnn(CC(=O)c3cc(C)[nH]c3C)n2)c1 +Cc1ccc(C(=O)Nc2ccc(C(N)=O)c(N3CCCCC3)c2)s1 +CCCc1nc(C(=O)NCCc2ncnn2C)cs1 +Cc1ccc(CC2(c3ccccc3)NC(N)=NC2=O)cc1 +COC(=O)Nc1cccc(NCC(=O)N(C)C2CCCCC2)c1 +Cc1cc(C)n(-c2cc3nc(C)sc3cc2N)n1 +Cc1coc(-c2cccc(NC(=O)Cc3cccc(OCC#N)c3)c2)n1 +CCOc1cc(C2NC(=O)N(C)C(C)=C2C(=O)OC)ccc1OC +Cc1oc(-c2cccs2)nc1CC(=O)N(C)Cc1ccc(O)cc1 +CCOc1ccc(C(=O)NCC#CCOc2ccccc2OC)cc1 +CSc1cc(-c2ccc(F)cc2)oc(=O)c1C#N +CC(Nc1cccc(NC(=O)CO)c1)c1cccc(F)c1 +CC1CCCN(C(=O)Nc2cc(C#N)ccc2OC(C)C)C1 +COCCn1ccc2cc(NC(=O)CNC(=O)OC)ccc21 +Cc1cc(C)c(C(=O)N(CCCO)C(C)C)c(C)c1 +CN1CCN(C(=O)C2CCCN2C(=O)c2csnn2)CC1 +CCCOC(=O)Cc1ccc(S(=O)(=O)N2CCCCC2)cc1 +COCC(=O)OCc1cc2cccc(C)c2[nH]c1=O +Cc1ccc(-c2ccc(C(=O)NC(C(N)=O)C(C)C)s2)o1 +O=c1c(-c2ccccc2)nnc2sc(Cc3ccccc3)nn12 +COCC(=O)Nc1cc(C(=O)OC)ccc1C(=O)OC +COc1cc(S(=O)(=O)N(C)C)c(OC)cc1Cl +CCn1cc(Br)cc1C(=O)NCCC(=O)N(C)C +COCC1(C(=O)N2CCCC(COc3ccc(F)cc3)C2)CCC1 +CN(C)C(=O)CNC(=O)c1cccc(OCc2ccccc2C#N)c1 +CC=Cc1ccc(OCC(=O)N2CCC(C(N)=O)C2)c(OC)c1 +CCC(C)c1ccc(C(=O)N2CCC(O)CC2)cc1 +CCc1cccc(CC)c1NC(=O)c1ccccn1 +COC(=O)CNC(=O)CSc1cc(C)ccc1C +Cc1cc(NC(=O)c2ccccc2F)cc2c1OCCO2 +COC(=O)c1cc(CSc2nncn2-c2ccccc2)oc1C +Cc1cccc(S(=O)(=O)CC(=O)NC(C)C2CC2)c1 +CCCC(NC(=O)CSc1nncs1)c1ccccc1 +CCC(NC(=O)NCc1ccnn1C)c1ccc2c(c1)OCCO2 +COc1ccc(NC(C)=O)cc1NC(C)C(=O)Nc1ccccc1 +Cc1cc(-c2ccc(O)c(F)c2)cn2nc(N)nc12 +CCCNC(=O)c1cnc(COc2ccccc2)nc1N +O=C1C(N2CCN(Cc3nccn3C(F)F)CC2)CCN1C1CC1 +CSc1cccc(NC(=O)Cc2csc(-c3ccoc3)n2)c1 +CCCOc1cn(-c2ccccc2)nc1C(=O)N1CCC(C)(C)C1 +C=C(C)CN(C)C(=O)Nc1ccc(NC(C)=O)cc1Br +Cc1cc(C)c(C(=O)Nc2nc(C(N)=O)cs2)c(C)c1 +Cn1nc2n(c1=O)CCN(CCOC1CCCCCC1)C2 +Cc1c(Br)c(C(=O)N2CCOCC2)nn1C +COCc1ccc(C(=O)Nc2cc(F)c(OC)cc2OC)o1 +CNC(=O)c1ccc(NC(=O)NCCCOC)cc1 +CC(CN1CCOC1=O)NC(=O)c1c(F)cccc1Br +O=C(CCn1cncn1)N1CCC(c2ccnc(-c3ccncc3)c2)C1 +O=C(CCCNC(=O)c1cccs1)NC1CCCCCC1 +O=C(NCCC1CN(Cc2cccc(O)c2)CCO1)c1cnon1 +Nc1cccc(C(=O)CNc2ccccc2Cl)c1 +CCOc1ccc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)cc1 +CC(CN1CCOCC1)NC(=O)NC(C)c1cccs1 +COC(=O)CCCNc1cc(C)nc2nc(-c3ccccc3C)nn12 +CC(=O)Nc1ccc(SCc2coc(-c3cccs3)n2)cc1 +CS(=O)(=O)N(Cc1cccs1)Cc1cccs1 +COc1cc(C)c(S(=O)(=O)n2ccc(C)n2)cc1C +N#Cc1cccc(C(=O)NCC#CCOc2ccccc2F)c1 +CC(C)(C)NC(=O)Cn1nnc(-c2ccc(N)cc2)n1 +CCc1n[nH]c(C2CN(C(=O)c3ccc4c(c3)CCCC4)CCO2)n1 +COC(=O)C1CCCCCC1NC(=O)CCc1cn(C)nc1C +Cc1nc(Cc2noc(-c3cc(C(C)(C)C)n[nH]3)n2)no1 +COC(=O)CC(C)NC(=O)C(C)Oc1ccc(F)c(F)c1 +O=C(Cc1c[nH]c2ncccc12)NCc1csc(=O)[nH]1 +CC(=O)N1CCc2ccc(S(=O)(=O)NC3CCCCCC3)cc21 +COc1cccc(CC(=O)NCc2ccc(Cn3ccnc3)cc2)c1 +CCC(CNC(=O)c1ccn(C)c(=O)c1)Oc1cccc(C)c1 +Cc1cc(OCc2cccc(C#N)c2)ccc1NC(=O)c1cn[nH]n1 +Cc1ccccc1C(=O)NCC(=O)NC1CCC(C)CC1 +CNC(=O)c1cc(NC(C)c2ccc(C)o2)ccn1 +CC(=O)c1ccc(C(=O)N2CCC(Oc3cccc(F)c3)CC2)s1 +Nc1cccc(-c2nnc(C=Cc3ccc(O)cc3)o2)c1 +O=C(Nc1ccc(F)cc1)NC1CCc2ccccc21 +CCC(CC)N(C1CC1)S(=O)(=O)c1ccc2c(c1)CCO2 +NC(=O)c1ccc(C#CCNC(=O)c2ccc3[nH]ccc3c2)cc1 +CNC(=O)c1cnc(-c2ccccc2OC(C)C)nc1N +Cc1csc(C(C#N)C(=O)c2cccc3c2ccn3C)n1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3cc4ccccc4o3)c2)n1 +c1ccc(OCc2nc(Cn3cncn3)cs2)cc1 +CCNc1nc(-c2cc(C)nn(CCC(C)C)c2=O)cs1 +COc1cccc(CN2CCN(c3nc(C(N)=O)cs3)CC2=O)c1 +COc1ncccc1C(=O)N1CCC(C(O)c2ccc(F)cc2)CC1 +CCNC(=O)c1cccc(NC(=O)c2cc(Cl)ccn2)c1 +CC(=O)N1CCC(C(=O)Nc2cc(C#N)ccc2Cl)CC1 +CC(=O)NCCNC(=O)c1ccc2c(c1)nc(C)n2C +CCOc1ccccc1NCC(O)c1ccc(C)cc1 +CC(C)c1ccccc1NC(=O)c1nc2ncccn2n1 +COC(=O)CCNc1ncc(Br)c2c(F)cccc12 +O=C(NCCNc1cnccn1)N1CCC1c1ccccc1 +COc1cc(C)c(NC(=O)c2ccccc2Cl)cc1OC +O=C(c1nc2c(s1)CCCC2)N1CCn2cncc2C1 +COCC1CCN(C(=O)c2cccc(CCC(C)(C)O)c2)C1 +CCCCNC(=O)c1cc2c([nH]c1=O)CCC(C)C2 +O=C(CCOCC1CCCO1)Oc1cccc2ccccc12 +c1ccc(CN(CCN2CCOCC2)c2ccccc2)cc1 +N#Cc1ccc(NC(=O)Nc2ccc(N3CCNC3=O)cc2)cc1 +OC(c1ccccn1)C1(c2ccc(Cl)cc2)CCOCC1 +Cc1cc(C)c(C#N)c(NC2CC(=O)N(C3Cc4ccccc4C3)C2)n1 +CC(=O)NCCCSc1nncn1-c1cccc(Cl)c1 +O=C(NCC1=CC=CC2N=CC=C12)c1cnc(-c2cccnc2)nc1 +CN1CCC(C(=O)N2CCOC(c3ccc(Cl)cc3)C2)CC1=O +Cc1cccc(CNc2ccc3nnc(C)n3n2)c1 +CCc1nn(C)c2[nH]nc(NC(=O)C3CCc4ccccc43)c12 +CCC(=O)N1CCN(CC(=O)N2CCc3ccccc32)CC1 +CCN(CCC#N)C(=O)Cn1nnc(-c2cccs2)n1 +Cc1sc(=O)n(CC(=O)NCC(C)(C)c2ccncc2)c1C +CCc1ccccc1N1CC(C(=O)Nc2ccc(Cl)cn2)CC1=O +CCN(C(=O)NC1CCN(C(C)=O)CC1)C(C)C(C)C +COc1cc(CNC(=O)c2csc(-c3ccsc3)n2)ccn1 +Cc1nnc2c3ccccc3nc(NCc3cccnc3)n12 +O=C(CNC(=O)NCc1ccc(F)cc1)Nc1cc(F)cc(F)c1 +CCOc1cc(C)ccc1NC(=O)Nc1cnn(CC2CCCO2)c1 +CCOCCC(=O)Nc1cc(-c2nnc3n2CCCCC3)ccc1F +Cc1n[nH]c(C)c1CCOC(=O)c1ccc(OC(C)C)nc1 +O=C(NCCNC(=O)c1cnccn1)c1ccc(Cl)cc1 +Fc1cccc(-n2nnnc2SCc2nc3ccccc3o2)c1 +CCCn1nc(-c2ccc(C)cc2C)cc(C#N)c1=O +Nc1ccc(-c2ccccc2)n(CC2CCCO2)c1=O +COCCOc1ccccc1C(=O)Nc1ccc(C)c(NC(C)=O)c1 +Cc1ccccc1CS(=O)(=O)NC(CO)Cc1ccccc1 +CC(C)N(C(=O)Cn1nc2c3ccccc3ncn2c1=O)C(C)C +Cc1ccc(CNC(=O)NC(C)C2CCCO2)cc1 +CC(=O)N1CCC(C(=O)N2CCC(Cc3ccccc3)CC2)CC1 +CC(=O)NCCNC(=O)CNC(=O)Cc1ccccc1 +COc1ccc(S(=O)(=O)N2CC(NC(=O)CC(C)(C)C)C2)cc1 +Cc1cc(N)cc(S(=O)(=O)Nc2ccccc2C)c1 +C=CCOC1CCN(C(=O)c2cccs2)C1Cc1ccncc1 +COc1cc(OC)c(-c2cc(C#N)c(C3CC3)o2)cc1OC +CCC1C(=O)Nc2c(F)cc(C(O)COC)cc21 +C#CCNC(=O)N1CCC(n2cccc2C(=O)OC)CC1 +Cc1cc(C(=O)N(C2CC2)C(C)c2ccccc2Cl)no1 +COc1ccccc1-n1cc(C(=O)NCCN2CCNC2=O)cn1 +CC(C)N(C(=O)CN1CCN(c2ccccc2F)C1=O)C(C)C +Cc1ccc(NC(=O)Cc2noc(-c3ccc(Cl)cn3)n2)cc1 +COC(=O)Cn1ccc(NC(=O)c2cc(C)cc(Cl)c2)n1 +CC(=O)Nc1nc(C(=O)NCC2(C(N)=O)CCOCC2)cs1 +CCCNC(=O)c1cc(OCC(=O)N2CCCCC2)n(C)n1 +c1cc2ncc(CN3CCCC(CN4CCOCC4)C3)cc2s1 +COCc1ncc(C(=O)N2CCCC(C)C2)c(N)n1 +CC(C)C(C(=O)N1CCN(c2ncccn2)CC1)n1cncn1 +CC(C)C(=O)c1ccccc1NC(=O)c1ccc(C(F)(F)F)nc1 +O=c1ccccn1CCNc1ncc(Br)cn1 +Cc1nc(C)c(C(=O)Nc2ccn(-c3ncccc3Cl)n2)o1 +O=C(NCC1(c2ccccc2)CCOCC1)C1(c2cccs2)CC1 +CC1c2ccsc2CCN1C(=O)c1ccc(Cn2cccn2)cc1 +Cn1nnc(-c2cccc(NC(=O)c3ccc4ccn(C)c4c3)c2)n1 +O=C(OCCCc1cccnc1)C1(c2ccc(F)cc2)CC1 +Cc1nn(-c2ccc(Cl)cc2)cc1C(=O)NC1CC(=O)N(C)C1 +O=C(NC1CCN(c2ccccc2)C1)N1CCCCC1c1cn[nH]c1 +CC(OCC(F)(F)F)C(=O)Nc1cccc2cn[nH]c12 +c1ccc(C2=Nc3ncnn3C(c3ccc4c(c3)OCO4)C2)cc1 +Cc1ccnc(NC(=O)CCOc2cccc(C)c2C)c1 +COc1cc(C(=O)N(C)C(c2cccnc2)C(C)C)ccc1F +Cn1nc(C(=O)OCc2nccs2)ccc1=O +N#Cc1ccnc(SCC(=O)Nc2ccncc2)c1 +CCOC(C)c1nc(CSc2nnc(C(C)C)n2C)cs1 +CCOC(=O)CNC(=O)c1cccnc1Oc1ccc(Cl)cc1 +CCN(C(=O)c1ccc(OC)c(N)c1)c1ccccc1C +CC(=O)Nc1cc(NCc2ccc(OCC(F)F)cc2)ccc1F +COCCN(Cc1ccsc1)C(=O)Nc1ccc(OC)cc1 +CC(NC(=O)c1ccc(S(C)(=O)=O)cc1)C(C)(C)C +Cc1cccc(CSc2nc3c(=O)[nH]cnc3n2C)c1 +CCCOCC1CCN(C(=O)c2cc(-c3ccc(OC)cc3)n[nH]2)C1 +Cc1nc(C)c(C(=O)Nc2cccc(C(=O)NC(C)(C)C)c2)s1 +CCN1CCN(C(=O)c2nnsc2-c2ccc(C)cc2)CC1 +COc1ccccc1NS(=O)(=O)c1cc(F)ccc1F +CCC(C)(CNC(=O)CC1C=CCC1)N1CCOCC1 +C#CCNC(=O)CSc1nnc(-c2cccc(C)c2)n1CC +CCN(CC)S(=O)(=O)c1ccc(=O)n(CCn2cccn2)c1 +CC(OC(=O)c1ccn(-c2ccccc2Cl)n1)C(N)=O +Cc1cc(C(=O)N(C)CC(=O)Nc2c(C)cccc2C)c(C)s1 +O=C(NC1CCCCC1)c1ccc(-n2cnnn2)cc1 +COCCOc1ccccc1C(=O)Nc1cc(N)ccc1OC +Cc1cc(C(=O)NC2CCCC2)ccc1NC(=O)c1ccco1 +CCc1ccc(-n2nc(CO)c(C(=O)NC(C)C)n2)cc1 +O=C1CC(CCc2ccccc2)c2c(nc3sccn23)CN1 +Cc1ccc(NC(=O)c2ccn(-c3ccccc3)n2)c(F)c1 +COc1cc(Cl)c(C)cc1NC(=O)c1cc(C)n[nH]1 +CC(C)NC(=O)c1cc(-c2cccc(Cl)c2)[nH]n1 +CC(=O)Nc1cccc(NCc2c(C)nn(-c3ccccc3)c2C)c1 +CCS(=O)(=O)NCc1cccc(S(=O)(=O)N2CCCCC2)c1 +COc1c(N)ccc2c1N(C)S(=O)(=O)C2(C)C +CC(C)C(=O)NCC1CCCN(C(=O)Cc2ccc(Cl)cc2)C1 +Cc1cccc(OCCN2C(=O)COc3c(N)cccc32)c1 +COc1ccc(-c2nnc3sc(Cc4c(C)noc4C)nn23)cc1 +Cc1nc2ccccc2n1CCNC(=O)COc1cccc(Cl)c1 +Cn1cnc(CNC(=O)C2(c3ccc(Cl)cc3)CC2)n1 +CN(Cc1ncc(-c2ccc(F)cc2)o1)Cc1nccn1C(F)F +Cc1cc(C(=O)Nc2nc(-c3ccc(C)s3)cs2)no1 +COC(=O)c1cccc(NC(=O)c2ccc(OC(C)=O)cc2)c1C +CCN(CCO)C(=O)NCCCn1c(C)nc2ccccc21 +Cc1nc(C(=O)N(C)CC(=O)N(C)C)nn1-c1ccccc1C(C)C +Cc1ccc2c(c1Cl)CCNC2c1ccc(F)cn1 +CC(C)CNC(=O)c1cccc(NC(=O)Cc2cccs2)c1 +CCCC(=O)Nc1nn2c(-c3cccc(C)c3)nnc2s1 +O=C(NCc1ccccc1)C1CC(=O)N(Cc2ccco2)C1 +CC(=O)Nc1ccccc1OCC(=O)N1CCc2ccccc21 +COCc1nn2c(-c3ccncc3)ccnc2c1-c1ccc(F)cc1 +CC(=O)N(Cc1ccccc1)c1nc(C)c(C(=O)N2CCCC2)s1 +COC(=O)CC(NC(=O)C1CCC1)c1ccccc1 +Cc1cccc2c1C(c1cc(=O)[nH]c3ccccc13)NCC2 +CCOc1ccc(NC(=O)Nc2ccccn2)cc1F +COc1ccc(C2CC(=O)c3cc(N)ccc3O2)cc1 +COc1ccc(NC(=O)Nc2ccc(F)c(F)c2)cc1 +COc1ccc(NC(=O)N2CCCC2C(=O)NCc2ccco2)cn1 +COC(C)(C)CC(C)NC(=O)N(C)C(C)c1ccco1 +COc1cc(C(C)=O)ccc1OCC(=O)N(C)C1CCCCC1 +Cn1cc(CC(=O)NCc2cccc(Cl)c2)c2cccnc21 +CCOC1CC(N(C)c2ncnc3c2cnn3C)C12CCCC2 +Cc1cc(CNc2cnn(-c3ccccc3F)c2)c(C)o1 +Cn1c(C2COCCN2)nc2cc3c(cc21)OCCO3 +Cc1ccsc1C(=O)N1CCn2c(-c3ccccc3)cnc2C1 +CCCCNC(=O)NCC(C)N1CCN(c2ccccc2)CC1 +Cn1c(CO)cnc1SCCC(=O)NCc1ccc(F)cc1 +COc1ccc2c(c1)[nH]c1c(=O)n(CC3CCCO3)cnc12 +O=C(NCc1ncc[nH]1)Nc1cc(F)ccc1N1CCCCC1 +COc1cccc(C(=O)N2CCC(c3nc(C)no3)CC2)c1F +CN(Cc1cccnc1)Cc1cn2c(n1)CN(c1ncccn1)CC2 +OCc1nc2ccc(F)c(F)c2n1CC(F)(F)F +CC(C)NC(=O)C(C)n1c(=O)c(C(F)(F)F)nc2ccccc21 +CC1CCN(C(=O)c2cnn(-c3ccccc3)c2)c2ccccc21 +CC(Sc1nncn1-c1ccccc1)C(=O)NC1CCCCC1 +Cc1nc(C(=O)OCCN2CCOCC2)cc2c1[nH]c1ccccc12 +COC(=O)Cc1ccc(NC(=O)CSc2nc(N)cc(=O)[nH]2)cc1 +Cn1cnc(S(=O)(=O)N(Cc2ccccc2)Cc2cccs2)c1 +O=C(Nc1cnc2ccccc2c1)c1coc(=O)c(Br)c1 +CC1CN(C(=O)c2cc(C3CC3)on2)C(C)CO1 +Cc1n[nH]c(C2CN(CC3CCCO3)CCO2)n1 +CC(C#N)NS(=O)(=O)c1ccc(F)c(Cl)c1 +Cc1cc(C)cc(N(CCCO)S(C)(=O)=O)c1 +CCCOc1nc(OCc2ccccc2)ccc1N +CCC(Oc1ccccc1F)C(=O)NCc1ccco1 +CC1CC1c1ccc(CNc2ccc(C#N)cc2)o1 +O=c1[nH]nc(SCc2cn3cccnc3n2)c(=O)[nH]1 +COCc1cccc(CNC(=O)CC2C=CCC2)c1 +Cc1nnc(SCc2coc(-c3ccccc3)n2)n(N)c1=O +Cc1csc(Cc2nc(-c3ccc4c(c3)CC(=O)N4)cs2)n1 +Cc1nc(C2CCN2S(C)(=O)=O)cc(N(C)CCO)n1 +CC(C)OCCOC(=O)c1ccc(C(=O)N(C)C)cc1 +Cc1c(C(C)NC(=O)N(C)CCn2cccn2)oc2ccc(F)cc12 +CCN1C(=O)COc2ccc(-c3cnoc3N)cc21 +CC(=O)c1cccc(NCc2cnn3ccccc23)c1 +COc1ccc(CC(=O)Nc2cccc(-c3ccc(=O)n(C)n3)c2)cc1 +COc1ccc(CC(=O)Nc2ccccc2N2CCOC2=O)cc1 +Cc1cc(C)c(C(=O)N2CCC(CC(=O)N3CCCCCC3)CC2)[nH]1 +N#CCc1nc(-c2c(Cl)cccc2Cl)no1 +CCOc1ccc(CC)cc1S(=O)(=O)N1CCCCC1 +CCC1CCCCC1OCC(=O)N1CCC(=O)CC1 +Cc1nnc(C2CCCN(C(=O)c3cccc(Cl)c3)C2)s1 +CC(C)c1ccc(S(=O)(=O)CC2CCOCC2)cc1 +COc1ccc(NC(=O)c2c[nH]c3ncccc23)cc1 +O=C(CCC(=O)c1ccccc1)NCCc1nc2ccccc2s1 +CC(C(N)=O)n1c(-c2ccccc2)cc2c1CCCC2 +Cn1cc(CCNS(=O)(=O)c2ccc3c(c2)OCCCO3)cn1 +Cc1ccc2c(c1F)CCNC2c1ccncc1Cl +Cc1n[nH]c2c(Nc3cnn(Cc4cccc(F)c4)c3)ncnc12 +CC(CN1CCOCC1)n1cncc1-c1c[nH]nc1-c1ccccc1 +Cc1nc2cc(C(=O)N3CCC(C)CC3C)ccc2n1C +COCCN(CCO)C(=O)Nc1cccc(C(=O)N2CCCC2)c1 +Nc1c(Cl)ccc2c1CS(=O)(=O)N(C1CCCCC1)C2 +Cc1nc2cc(NC(=O)CCn3ccc4ccccc43)ccc2o1 +COc1ccc(C)cc1C(=O)NCCOCCO +Cn1ccc(C(=O)Nc2cnn(Cc3ccc(Cl)cc3)c2)cc1=O +CCCN(C)C(=O)C(C)NS(=O)(=O)c1cccs1 +CCCC(=O)N1CCC2(CC1)CN(C(C)CCC)C(=O)O2 +Fc1ccc(-c2nn(Cc3ccncc3)c3c2CNCC3)c(F)c1 +COCCn1cc(CC(=O)NCC2CCOCC2)c2ccccc21 +CC(C)(C)c1n[nH]cc1CN1CCOC(c2nccs2)C1 +CCN(C)C(=O)c1ccc2c(c1)CCCN2S(C)(=O)=O +Cc1cccc(C)c1NC(=O)CCC(=O)c1cccc(N)c1 +COc1ccc(CC(C)CNC(=O)c2ccccn2)cc1 +Cc1noc(C23CCOC2CCN(C(=O)c2sccc2C)C3)n1 +COc1ccc(NS(=O)(=O)c2ccc3c(c2)CC(=O)N3)cc1OC +O=C(Nc1ccc(NCCc2ccccc2)cc1)C1CCOC1 +Cc1ccc(-n2c(=O)[nH]c3c(C(N)=O)nc(-c4ccco4)nc32)cc1 +COc1ccccc1Nc1ccc(S(=O)(=O)N(C)C)cn1 +O=C(Nc1cccc2[nH]cnc12)c1ccc2[nH]cnc2c1 +O=C(Nc1ccncc1)N1CCN(CCOc2ccccc2)CC1 +COc1ccc(C(=O)N(C)C(C)c2ccco2)cc1OC +O=C(NCCCN1CCCCCC1=O)c1ccccc1O +COc1ccc(OC)c(NCCNc2ccccc2F)c1 +Cc1nc(-c2ccc(C)c(NC(=O)CN3CC(C)OCC3C)c2)n[nH]1 +O=C(CCn1ccccc1=O)Nc1ccnn1C1CCCCC1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1ccccc1C +O=C1CCCN1Cc1nnc(SCc2ccc3c(c2)CCC3)o1 +CCc1ccc(S(=O)(=O)N(C)c2ccc(OC)nc2)cc1 +COC(=O)CCC(C)(C)NC(=O)Cc1c[nH]c2ccc(F)cc12 +Cc1ccccc1OC(=O)Cc1csc(C(C)C)n1 +CNS(=O)(=O)c1ccc(OC)c(C(C)(C)C)c1 +CC(C)(O)CCc1ccc(C(=O)N2CCCC(C#N)C2)cc1 +CCc1cc(C(O)c2ccc(C)cc2)cc2c1NC(=O)C2 +Cc1c(Cl)ccc2c(=O)c(C(=O)NCCc3ccccc3)c[nH]c12 +CC1(C)CC(=O)c2cnc3nc(SCC#N)nn3c2C1 +CC(NC(=O)CSc1cc(C#N)ccn1)c1ccco1 +O=C(NCC1CCCCN1C(=O)COCC1CC1)Nc1ccccc1 +CCC(C)(C)NC(=O)CSc1ccc(N)cc1C +Cc1cnc(NC(=O)NCC(c2ccccc2)N2CCOCC2)s1 +CC1(NC(=O)NCc2ccccn2)CCCc2ccccc21 +CN(Cc1c(F)cccc1Cl)C(=O)c1ccccc1F +CCOC(=O)c1ccc(NC(=O)Cn2c(=O)[nH]c3ccccc32)cc1 +CSc1ncnc(Nc2cnn(Cc3ccc(F)cc3)c2)c1C#N +Cc1cc(C)n(-c2ccc(Cl)c(C(=O)N3CCCC(C)C3)n2)n1 +CNC(=O)c1ccc(Cl)c(NCc2ncc(-c3cccs3)o2)c1 +Nc1ccc(-c2cn3c(n2)sc2ccccc23)cc1 +O=C(NCCCn1cnc2ccccc21)c1ccc(Cl)cc1 +Cc1ccc(OCCC(=O)NCc2ccoc2)cc1C +COCC(C)(C#N)NC(=O)c1ccc(OC)cc1OC +CCCNC(=O)CCC(O)c1ccc(OC)c(N)c1 +Cc1ccc(C(=O)Nc2sccc2C(N)=O)cn1 +N#CCCN(Cc1cccnc1)C(=O)C1CC(=O)N(c2ccccc2)C1 +O=C(Nc1ccc(OCc2cccnc2)cc1)N1CCOCC1 +CCOc1ccccc1NC(=O)c1ccc(NS(=O)(=O)CC)cc1 +CC(C)c1ccsc1C(=O)NCCCn1cccn1 +CCOC(=O)c1ccsc1NC(=O)COc1ccccc1F +COc1cccc(NC(=O)NCCC(O)C(F)(F)F)c1 +NC(=O)c1n[nH]c2ccc(NC(=O)CCc3ccncc3)cc12 +CC(=O)N(Cc1nccn1Cc1ccccc1)CC1CCCO1 +CC(NC(=O)c1csnn1)C(=O)N1CCCC1 +CC1CC(=O)Nc2c(cc(Cl)c(N)c2Cl)O1 +COc1ccccc1C(=O)OCC(=O)c1ccccc1F +COCC(=O)N1CC2COCC2(COc2cccnc2)C1 +CCC(C)(C)NC(=O)CS(=O)(=O)c1ccc(Br)cc1 +O=S(=O)(NC1CC1)c1ccc2c(c1)OCCO2 +CCC1COCCN1Cc1ccccc1N1CCOCC1 +COc1ccc(C(=O)Nc2ccc(C(C)C)cc2)nn1 +CC(NC(=O)c1ccccc1O)c1ccc2c(c1)NC(=O)CO2 +c1ccc(-c2csc(SCc3noc(C4CC4)n3)n2)cc1 +COC(C)(C)CC(C)NC(=O)NC1(C)Cc2ccccc2C1 +C=CCNS(=O)(=O)c1ccc2c(c1)CCCN2C(C)=O +Cc1n[nH]c2c1CNc1ccc(Br)cc1-2 +NC(=O)CSc1nc(=O)n(CC2CCCO2)c2c1CCC2 +O=c1sc(=O)c2sc3c(=O)sc(=O)c3sc12 +N#Cc1ccccc1Cn1c(-c2ccccn2)noc1=O +CC(C)Oc1cc(N2CCC(O)CC2)ccc1N +CCOC(=O)c1cccc2cnn(-c3ccncc3)c12 +CC(C)(C)C(=O)N1CCCN(C(=O)c2ccccc2)CC1 +O=C(Cn1ccc(C(F)(F)F)n1)Nc1ccc(CCO)cc1 +O=C(CCN1CCOCC1)c1cc(F)ccc1F +Cc1noc(COC(=O)Cn2nnc3ccccc3c2=O)n1 +Cc1cc2c(=O)n(CCSc3ncn[nH]3)cnc2s1 +Cc1cc2oc(=O)cc(CNC(=O)C3CCCO3)c2c(C)c1Cl +CCC(C)OCCCC(=O)Nc1ccc(Cl)cc1N +CCOc1ccccc1-c1nccn1-c1cccc(N2CCCC2=O)c1 +Cc1ccc(CN(C(=O)CN2CCOC(C(N)=O)C2)C2CC2)cc1 +CC(C)c1ccc(NC(=O)N2CCC3(CCC(=O)N(C)C3)CC2)cc1 +O=C(C1CCCc2ccccc21)N1CCC(Nc2cccnn2)CC1 +CCc1ccc(CN(C)C(=O)c2ccccc2S(C)(=O)=O)cc1 +CCc1ccc(C(C)NC(=O)c2ccc(C(=O)N(C)C)cc2)cc1 +Cc1ccccc1-c1c(CO)nnn1Cc1ccc(F)cc1 +O=C(c1cccnc1)N1CCN(C(=O)c2ccco2)CC1 +COCc1ccccc1NCC(=O)NCc1cccs1 +O=C1COc2cc(C(=O)NCCOc3cccc(F)c3)ccc2N1 +COc1cc(N2CCCC(N(C)C(=O)OC(C)(C)C)C2)ncn1 +Oc1ccc(Cl)c2c1CCNC2c1cncnc1 +Cc1ccc(CC(=O)OCCCc2cccnc2)s1 +Cc1ccc(NC(=O)C(O)c2ccc(F)cc2)c(C)c1 +CCC(NC(=O)NCC(O)c1ccc(F)cc1)c1ccc(OC)cc1 +O=C(CCCn1c(=O)oc2ccccc21)Nc1ccc(F)c(Cl)c1 +c1coc(CNc2nc3ccccc3c3nc(-c4ccncc4)nn23)c1 +Cc1c(NC(=O)C2CC2)cccc1NC(=O)C(C)(C)C +Cn1cnc(-c2nc(C(=O)NCc3ccsc3)c3ccccn23)c1 +CC(C)(C)n1ccc(C(=O)N2CCC3(CCCN(CCO)C3=O)C2)c1 +Cc1csc2nc(Cc3c[nH]c4ccccc34)[nH]c(=O)c12 +COc1ccc(C(=O)NC(c2ccc(F)cc2)C(C)(C)C)nn1 +COc1ccc(C(=O)Nc2ccc3c(c2)OCO3)c(F)c1 +Cn1cccc1C1CCCCCN1C(=O)c1ccccn1 +CNS(=O)(=O)c1ccc(C)c(NC(=O)Nc2cc(C)cc(C)c2)c1 +COC(=O)c1cccc(NC(=O)CCc2ccsc2)c1 +Cc1noc(C)c1CCC(=O)NCC1(CO)CC1 +O=C(CC1CCCC1)N1CCC(=O)N(Cc2ccccc2F)CC1 +CCCN(CC(=O)OC)S(=O)(=O)C1=Cc2ccccc2CC1 +Cc1[nH]ccc1C(=O)N1CCCCCC1CC(O)c1ccco1 +COc1ccc(F)cc1NC(=O)NCCc1nc(C)no1 +c1ccc2c(c1)oc1c(NC(c3nccs3)C3CC3)ncnc12 +Cc1ccc(-n2nnnc2SCc2nc(C)c3ccccc3n2)cc1 +O=C(CO)N1CCN(Cc2nnc(C3CC3)o2)CC1 +Cc1c(S(=O)(=O)Nc2ccccc2C(N)=O)cnn1C +COc1ccccc1CNC1COc2c(cccc2OC)C1 +CCCc1nc(C)c(CNc2ccc3cc[nH]c3n2)s1 +Cc1nc2cc(NC(=O)c3[nH]c4c(c3C)C(=O)CCC4)ccc2o1 +C#CCOc1ccc(F)cc1NC(=O)Cc1ccc(F)c(F)c1 +O=C(NCCOc1cccc(F)c1)c1n[nH]c(=O)[nH]1 +COc1cccn(CC(=O)N2CCC(n3nc(C)cc3C)C2)c1=O +Cc1cnc(C(=O)Nc2ccc(F)c(C(N)=O)c2)cn1 +O=C(Cc1ccon1)NCCc1ccc(OC(F)(F)F)cc1 +N#Cc1cccc(C(=O)NCC#Cc2ccc(F)cc2)c1 +CCC(NC(=O)c1cc2ccccc2oc1=O)c1ccc(OC)cc1 +CCOCC(C)NC(=O)c1cc(Br)c[nH]1 +Cc1nn(-c2ncccc2Cl)c(C)c1Br +CC(NC(=O)c1nc2ccccc2c(=O)[nH]1)c1ccc(F)c(Cl)c1 +c1csc(CN2CCOC3CC(COCc4ccncc4)CC32)c1 +CC(C)(C)OC(=O)n1cc(CO)c2cc(C#N)ccc21 +CC(=O)c1cc2cc(Br)cc(Br)c2oc1=O +CC(C)C(C)NC(=O)CCNS(=O)(=O)c1cccs1 +Cc1c(Cl)cccc1-n1nnc(C(=O)OC(C)C)c1C +CC(C)(C)C(=O)N1CCOc2ccc(NC(=O)c3ccco3)cc21 +COc1ccc(C2NCCc3c(F)cc(O)cc32)cc1F +CCC(=O)Nc1ccc(NCC(=O)N(CC)c2ccccc2)cc1 +O=C(Cc1cccc2ccccc12)N1CCNCC1 +O=C(c1cccc(Br)c1)N(CC(F)(F)F)C1CC1 +CCc1nc2n(n1)CCCC2NC(=O)N(CC1CC1)CC1CC1 +Cc1ccc(CNC(=O)NC2CCN(S(C)(=O)=O)CC2)cn1 +COCC(=O)N1CC2OCCN(c3ccc(C)nn3)C2C1 +Cc1cnc(C(=O)Nc2nc(Cc3ccccc3)cs2)cn1 +CC(Nc1cc(N)nc(N2CCCC2)n1)c1cn2ccsc2n1 +O=C1CN(C(=O)Nc2ccc(F)c(F)c2)CCN1 +CN(Cc1cccn1C)C(=O)Nc1ccccc1F +CCC(O)CNc1nccc(-c2ccc(C)nc2C)n1 +Cc1nn(-c2nc(CC(=O)N3CCOCC3)cs2)c(C)c1Cl +O=C(Nc1ccsc1)C1COc2ccc(F)cc2C1 +CSc1ncccc1C(=O)Nc1nc(C)cs1 +COC(=O)Cn1c(-c2ccncc2)nc2cc(OC)ccc21 +Cc1cc(NCc2c(C)nn(C)c2C)ccc1C(=O)OC(C)(C)C +CC(=O)c1cccc(OC(C)C(=O)N(C)C2(C#N)CCC2)c1 +O=C(NCC1COc2ccccc2C1)c1ccccc1-n1cncn1 +CCCC(=O)Nc1ccc(CNC(=O)N2CCC(CO)CC2)cc1 +CCS(=O)(=O)N1CCCC(n2c(=O)n(C)c3cncnc32)C1 +Cc1ccc(-c2nc3c(C)cccn3c2CO)cc1 +Cc1cc(Br)ccc1NC(=O)c1nc2nccc(C)n2n1 +COc1cc(S(=O)(=O)Nc2ccc(C)cc2)ccc1NC(C)=O +Cc1n[nH]c(C)c1C(=O)NC(C)Cc1ccsc1 +Cc1ccc(C(C)(O)CNC(=O)Cc2c(F)cccc2F)o1 +CS(=O)(=O)c1ccc(-c2ccc(C#N)cc2)cc1 +CCCN(Cc1ccc(C#N)cc1)C(=O)c1ccnc(N(C)C)c1 +CCNC(=O)Cc1csc(NC(=O)c2ccc3c(c2)OCO3)n1 +CC(C)c1noc(CCNC(=O)NC(C)(C)c2cccc(F)c2)n1 +CNc1nc(-c2sc(-c3ccccn3)nc2C)cs1 +COc1cc(Cl)c(C(F)(F)F)cc1NC(C)=O +O=C(Nc1cccc(OCC2CCCO2)c1)c1ccccn1 +CCCOC(=O)C1=C(C)NC(=O)NC1c1ccc(C(=O)OC)cc1 +O=c1ccc(C(F)(F)F)cn1Cc1nnc(-c2cccs2)o1 +Cc1ccc(CC(=O)NCC(C)(C)c2ccncc2)cc1 +Oc1ccc(-n2cnnc2)cc1-c1nc2ccccc2s1 +O=C(c1n[nH]c2ccccc12)N1CCOC(c2ccccc2F)C1 +CC(C)(C)CC(=O)NC1CCN(C(=O)OC(C)(C)C)CC1 +Cc1csc(N2CCCN(Cc3cnn(C(C)(C)C)c3)CC2)n1 +CCN(C)C(=O)c1cc(-c2ccccc2)nc2c1cnn2C(C)C +Cn1cc(CC(=O)NCc2cc3ccccn3n2)c2ccccc21 +Cc1oc2nc[nH]c(=O)c2c1C(=O)N(C)CCOc1ccccc1F +CSc1nc(-c2ccc(Cl)cc2)nc(N)c1C#N +C=CCOC1CCC2C1OCCN2Cc1cccs1 +COc1ccccc1OCc1ccc(C(=O)N(C)CC2CC2)o1 +Cc1nc(S(=O)(=O)c2ccccc2)c(N2CCCCC2)o1 +O=C(COC(=O)c1ccccc1Cl)Nc1cccc(F)c1 +Cc1ccc(SCc2cccc(OCC(N)=O)c2)cc1 +COCCN(CCC#N)S(=O)(=O)c1ccc2oc(=O)ccc2c1 +CCC1COCCN1C(=O)Nc1cnn(Cc2ccccc2)c1 +Nc1nc(CN2CCN(C(=O)C3CCCC3)CC2)nc2ccccc12 +CN(C)c1ccc(NC(=O)COc2ccccc2)cn1 +CCOC(=O)c1coc(N(C)Cc2nc(-c3ccccc3)no2)n1 +Cc1cc(C)n(CCC(=O)N2CCC(=O)NCC2C)c(=O)n1 +C=CC(CC(=O)Nc1sccc1C(=O)NC1CC1)c1ccccc1 +CCc1nc(CN2CCCC2C(=O)OCc2ccccc2)cs1 +Cn1cc(OCc2ccccc2)c(=O)cc1C(=O)Nc1nncs1 +Cc1ccc(NC(=O)CNc2ccc(C(=O)N(C)C)c(C)c2)cc1 +CCN(Cc1noc(C)n1)C(=O)c1cc(COc2ccccc2)[nH]n1 +Cc1nnc(SCC(=O)Nc2ccccc2SCC#N)s1 +CN(Cc1ccncc1)c1cc(C(F)(F)F)nc(-c2cccnc2)n1 +N#Cc1cccnc1N1CCOC(c2noc(-c3ccccc3)n2)C1 +Cn1nc(C(=O)NCc2cn(-c3ccccc3)nn2)ccc1=O +CC(C)C(C#N)CC(=O)Nc1ccc2c(c1)OCO2 +CCOc1ncccc1C(=O)N1CCN(c2cccc(Cl)c2)CC1 +O=C(Nc1ccc(Br)cc1Cl)c1ncccc1O +CC(=O)c1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1C +COCC(=O)N1CCN(Cc2coc(-c3cccc(F)c3)n2)CC1 +CC(=O)N1CCc2cc(-c3cn4cc(N)ccc4n3)ccc21 +Cc1nc(-c2cccc(-c3ccnc4[nH]ccc34)c2)no1 +O=C(NCc1ccc(F)cc1)C1CCC(NC(=O)N2CCOCC2)C1 +Cc1nnc(C2CCCN(C(=O)Nc3cccs3)C2)s1 +Cc1nonc1Cn1ncc(N2CCOCC2)cc1=O +O=C(Cc1csc(-c2ccoc2)n1)NCC(=O)Nc1cccnc1 +CNC(=O)CSc1nnc(-c2ccc(O)cc2)o1 +CCC(C)n1ncc(C(=O)Nc2ccc(C(C)=O)cc2)c1C1CC1 +CNc1ccc(N(C)S(=O)(=O)c2ccc(C)cc2)cc1 +COc1c(Cl)cc(C(=O)OCC(N)=O)cc1Cl +CCOc1ccc(C2=CCN(C(=O)COC)CC2)cc1 +COc1c(Cl)cccc1NC(=O)c1ccsc1 +Cc1cc(N2Cc3ccccc3OCC2=O)ccc1F +CSc1ccccc1NC(=O)CCN1CCN(C(=O)C(C)C)CC1 +Cc1ccc(C(=O)NCCOc2ccc(Cl)cc2)cn1 +COCCc1nc2sc(C)c(-c3ccccc3)c2c(=O)[nH]1 +Cc1ccc(OC2CCN(C(=O)c3ccc(F)cc3Cl)CC2)nn1 +CN1CCc2nc(C(N)c3ccccc3F)sc2C1 +CC1CN(S(=O)(=O)c2cc(N)ccc2Cl)C(C)CO1 +CC(Cn1ccnc1)C(=O)N1CCN(c2ccccc2)CC1 +CC(C)(O)CCc1ccc(C(=O)NC2(C(N)=O)CCCC2)cc1 +Cn1ncc2c(N3CCC(c4nnc5ccccn45)CC3)ncnc21 +C#Cc1cccc(NC(=O)CCC(=O)Nc2nccs2)c1 +COc1ccc(OC)c(CN(C)C(=O)c2cc(Cl)ccc2O)c1 +Nc1cccc(-n2cc(-c3ccc(Br)cc3)nn2)c1 +NC(=O)Cn1cnc2c(nnn2-c2cccc(F)c2)c1=O +N#Cc1cccc(-c2cc(N3CCOCC3)nc(N)n2)c1 +CC(c1ccon1)N(C)C(=O)Nc1cc(C2CC2)nn1C +Cc1nn(-c2ccc3ccccc3n2)c2ncc(N)cc12 +COC(=O)CCn1c(-c2ccncc2)nc2ccc(F)cc21 +Cc1nc(-c2ccc(C(=O)Nc3ccc(Cl)cn3)cc2)no1 +C#CCOc1nc(N2CCOCC2)nc(N2CCOCC2)n1 +CCC(CC)N(C)C(=O)Nc1ccc(C(=O)NC)c(Cl)c1 +Cc1oc(=O)n(Cc2nc(-c3ccco3)no2)c1C +NC(=O)C1CCCN1C(=O)c1cccc(F)c1F +Cc1cc(C(=O)CCC(=O)NCc2nc3ccccc3[nH]2)c(C)s1 +O=C(NCCSc1ccccc1)NCc1nnc2ccccn12 +O=S(=O)(CCN1CCCc2ccccc21)c1ccccc1 +Cc1nc(C)c(C(=O)OCC(=O)c2ccc3c(c2)CCCC3)s1 +Cc1cc(NC(=O)CSc2ccc(NC(=O)C3CC3)nn2)on1 +Cn1cc(S(=O)(=O)Oc2cc(Cl)ccc2Cl)cc1C(N)=O +CCNC(=O)CCCc1nc(-c2ccccc2Cl)no1 +CCc1cccc2c(O)c(C(=O)N3CCC(C)CC3)cnc12 +COCCN(C)C(=O)C(C)Oc1ccc(Cl)cc1C +CNS(=O)(=O)c1ccc(N(CCO)C2CC2)c(N)c1 +OC(Cn1ccnc1)(c1ccccc1)c1ccccn1 +O=C(NCC1Cc2ccccc2O1)c1nc2ccccc2c(=O)[nH]1 +COc1c(S(=O)(=O)NCc2ccccn2)ccc(Cl)c1Cl +CCN(CC)C(=O)CCCC(=O)Nc1ccc(F)cc1 +CCc1noc(C)c1C(=O)N1CCN(c2cccc(C)c2)CC1 +COc1cc(-c2cc(SC)c(C#N)c(=O)o2)cc(OC)c1OC +O=C(Cc1ccccc1OCC1CC1)N1CCc2[nH]c(=O)sc2C1 +Cc1noc(-c2cccc(Br)c2)c1N +Fc1cccc(CNCc2ccncc2Cl)c1F +O=C(NCCO)C1CC(=O)N(Cc2ccccc2)C1 +COc1ccc(C(O)Cc2ccc(C)cc2)cc1OC +COc1ccc(C(=O)NC(C(=O)NC(C)CO)C(C)C)cc1 +CC(C)CCn1nc(-c2ccc(F)cc2F)cc(C#N)c1=O +NS(=O)(=O)N1CCC(c2nc3ccccc3o2)CC1 +COCCN(C)C(=O)c1ccc2nc(-c3ccc(F)cc3)cn2c1 +Cc1nc(-c2ccco2)ccc1C(=O)NCCOc1cccnc1 +O=C1OC2CC1N(C(=O)c1c(F)cccc1Cl)C2 +CCCCC(=O)N1CCCC(C(=O)NCCC)C1 +COc1ccc(CN(C)C(=O)c2ccc[nH]c2=O)cc1F +CC(C)(CNC(=O)c1ccc2nncn2c1)c1ccncc1 +CCCc1ccc(C(NS(N)(=O)=O)C(C)C)cc1 +CC(=O)N1CCN(Cc2nc(-c3ccc(F)cc3)oc2C)CC1 +CCC(CC)N(C)C(=O)c1cc(C)nc2c1c(C)nn2C +FC(F)COc1ccc(-c2nc(-c3ccsc3)no2)cn1 +N#CC(C(=O)C1CC1c1ccco1)c1ccccn1 +O=C(NCc1ccc2c(c1)OCO2)c1cc(-c2cccs2)on1 +CC(=O)Nc1cccc2c1ccn2CC(=O)NCc1ccccc1 +CC(CNC(=O)CCn1cncn1)N1CCOCC1 +COc1ccccc1-c1c(C)c(C)nc2ncnc(N)c12 +CCOc1cc(CNc2cccc(C#N)c2)cc(Cl)c1O +CN(CC1CC1)C(=O)CN(C)C(=O)c1ccccc1 +COCCCN(C)C(=O)NC(C)c1ccc(-n2cncn2)cc1 +O=C(Nc1ccc(F)cc1)N1CCC(n2cnc3cccnc32)CC1 +COC(=O)c1ccc(COc2ccc(C(C)=O)cc2)o1 +COCCN1CCN(C(=O)c2cncn2-c2ccccc2)CC1=O +CCCCN(Cc1ccccc1C)C(=O)c1cc(N)ccn1 +Cc1ccc(NC2CCN(C(=O)c3cccc4n[nH]cc34)CC2)nn1 +CCc1nc(C)sc1CNC(=O)Cc1c(C)nc2ccccn12 +CC1CN(C(=O)NCc2ccccc2Cn2cncn2)CCO1 +Cc1cc(Cl)ccc1OC(=O)Cc1c(C)noc1C +CCOC(=O)c1ccc(N2CCCC(O)C2)nc1 +CC(C)(C)c1cc(CNC(=O)c2cccc(Cn3cccn3)c2)n[nH]1 +O=C(Cn1cccn1)N1CCCC(CCc2ccccc2F)C1 +CCc1onc(C)c1NC(=O)N(C)CCc1nccs1 +O=C1NCCN(Cc2cc3cc(F)ccc3o2)C1c1ccccc1 +CN(CCC(F)(F)F)C(=O)Cc1noc2ccccc12 +NC(=O)CCSc1nnc(NCc2ccccc2)s1 +CC1CCN(C(=O)c2ccccc2NC(=O)NC2CCCC2)CC1 +COc1cc(N2Cc3cc(C)ccc3C2c2cnco2)ncn1 +CNC(=O)C1(NC(=O)CC(C)(C)C)CCCCC1 +Cc1nc(C(=O)Nc2ccc(OCc3ccccc3)cc2)co1 +CC(C)(C)c1ccnc(S(N)(=O)=O)c1OC1CC1 +CCOc1cccc(NC(=O)c2csc(S(N)(=O)=O)c2)c1 +FC(F)Oc1cccc2c1C(CC1CCOCC1)NCC2 +CN(C)C(=O)c1cc(NC(=O)NC2CCCc3sccc32)ccn1 +CN(C(=O)c1ccc(N)cc1)c1ccc(F)c(F)c1 +CCOC(=O)Cc1csc(NC(=O)c2c[nH]c3cccc(F)c23)n1 +CCCNC(=O)CNC(=O)NCC1(c2ccc(F)cc2)CC1 +CCn1nccc1C1CCCN1C(=O)Nc1ccsc1C(=O)OC +Cc1cc(C)c(CNC(=O)c2cnc3c(cnn3C(C)C)c2)c(=O)[nH]1 +COc1cccc(OCC(=O)Nc2ncc(C#N)s2)c1 +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccc(CNC(N)=O)cc1 +O=C(CCNC(=O)c1ccoc1)NCC1CCCCO1 +O=C(NCCNc1cc(N2CCCC2CO)ncn1)c1cccnc1 +CCC(Nc1ccc(C)cc1)C(=O)Nc1cc(C)on1 +O=C(Cc1ncc[nH]1)c1ccc(Cl)cc1Cl +CNC(=O)c1cccc(OC(C)(C)C)c1OC1CC1 +CCOCC(=O)NCc1cc2c(nc1OC)CN(C1CCCC1)C2=O +COCCN(C)c1ccc2c(CC(=O)OC)coc2c1 +CCCCN(C)C(=O)Nc1ccc(C)c(NC(C)=O)c1 +Cn1cnnc1Cn1nc(-c2cccs2)c2ccccc2c1=O +Cc1cc(-c2nc3ccc(S(C)(=O)=O)cc3[nH]2)on1 +CC(C)NC(=O)CSc1nnc2[nH]c(=O)cc(C(C)C)n12 +CN(C)C(=O)CCNC(=O)Nc1ccn(Cc2ccccc2)n1 +Nc1cccc2c(-c3ccccc3CN3CCOCC3)n[nH]c12 +CNC(=O)N1CCCC(C(=O)NC2CCCCC2)C1 +COC(=O)C1(N(C)C(=O)Cn2nc(C)ccc2=O)CCCCC1 +O=C(COCc1nc2ccccc2s1)Nc1nccs1 +COC(=O)C(NCC(F)(F)F)c1ccccc1C +COc1ccc(C(C)(C)CO)cc1Br +O=C(CCNC(=O)c1c[nH]nc1-c1ccccc1)Nc1nccs1 +NC(=O)NCc1ccc(NC(=O)c2cccc(Cl)c2)cc1 +CCCNC(=O)COc1ccc(Cl)cc1C(N)=O +CCc1ccc2oc3c(c(=O)c2c1)C(c1cccnc1)N(C)C3=O +COC(=O)CSc1nnc(-c2ccc(O)cc2)n1-c1ccccc1 +Cc1ccc(-c2nnc(S(=O)CC(=O)NC3CCCC3)n2C)cc1 +COc1cccc(N(C)c2nc(C)c(C(C)=O)s2)c1 +CCn1c(-c2ccccc2C)nnc1S(=O)(=O)CC(=O)NC1CC1 +O=C(NCc1ccc(F)cc1)c1ccc(-c2cccs2)nc1 +Cc1ccc(CNC(=O)C2CCC(=O)N2)c(Oc2ccccc2)c1 +COC(=O)C1CN(C(=O)c2ccncc2)CC1c1ccc(F)cc1 +CC(c1ccccc1)N1CC(C(=O)N(C2CCCC2)C2CC2)CC1=O +CCCNc1nc(-c2c(C)oc3c2CCC3)cs1 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccco2)cc1C +CC(C)(NC(=O)c1ccc(C#N)cn1)c1cccc(F)c1 +CC1CN(c2ncccc2C(F)(F)F)CC1(C)O +Cc1c(C(O)c2ccc(F)cc2)cc2c(c1C)NC(=O)C2C +CC(C)C(=O)NCCCNC(=O)c1nc2c(F)cccc2s1 +CCc1ccc(S(=O)(=O)N2Cc3cncnc3C2)cc1 +COCCN1CCN(C(C)=O)C(c2ccc(C(F)(F)F)cc2)C1 +COCCNC(=O)CC1(n2cccc2)CCCCC1 +Cc1cnn(CC2CCCN2C(=O)c2ccc(S(C)(=O)=O)cc2)c1 +O=C(COc1ccc2c(c1)CCC2)Nc1cccc(F)c1 +CC(C)NC(=O)c1ccc(Cl)c(NC(=O)C2CCCO2)c1 +Cn1cnc(S(=O)(=O)N2CCCC(c3nc4ccccc4[nH]3)C2)c1 +CN1CC(=O)N(c2cccc(F)c2)CC12CCN(C(=O)C1CCC1)C2 +COC(=O)c1cccc2nc(C(Cl)(Cl)Cl)[nH]c12 +O=C(CC1CCCCC1)NCCNC(=O)c1c[nH]c2cccc(F)c12 +CS(=O)(=O)N1CCCC(c2cccc(-c3cccnc3)n2)C1 +CCc1nc2ccccc2n1CC(=O)Nc1ccc(OC)nc1 +CCc1ccc(C(O)CN2CCN(c3ncccn3)CC2)cc1 +CS(=O)c1ccc(CNCC2(c3ccc4c(c3)OCO4)CC2)cc1 +CCOc1cccc(NC(=O)c2c(F)cccc2F)c1 +O=C(Nc1ccccc1C(F)(F)F)c1ccc(O)cc1 +O=C(Cn1ccnc1)Nc1ccc(F)c(Cl)c1 +COc1cc(C)c(C(=O)Nc2cccc(C)c2C(N)=O)cc1OC +O=C(NCCO)NCCc1cccc(-c2ccccc2)c1 +CC(C)CNC(=O)CCCn1nnc2ccccc2c1=O +CC(=O)N1CCC(N(Cc2ccco2)C(=O)Nc2ccccc2)CC1 +O=C(Cn1cc(Cl)cn1)N1CCCCC1c1cc[nH]n1 +Cc1cccc(CS(=O)(=O)N2CCCCCC2)c1 +O=C1CC(c2ccc(O)cc2)c2ncn(-c3cccc(F)c3)c2N1 +N#Cc1ccccc1NC(=O)CCS(=O)(=O)N1CCNCC1 +CCOc1ccc(F)c(C(=O)Nc2cc(CC)n[nH]2)c1F +COC(=O)C1=C(c2ccc(OC)cc2)NC(=O)NC1c1ccncc1 +CNc1nc(SCC(=O)Nc2ccccc2C#N)nc2ccccc12 +CNC(=O)N(Cc1ccc(O)c(OC)c1)C1CC1 +CC(=O)c1ccc(NC(=O)c2cnn(-c3cccc(Cl)c3)c2)cc1 +CSc1nc(-c2ccccc2)cn1Cc1nnc(C2CC2)o1 +COc1ccc(-n2cnnc2SCC(=O)N2CCC2)cc1 +O=C(Cc1cccc(CNC(=O)c2cc3cccnn3c2)c1)NC1CC1 +CCc1cc(NCCn2c(C)cc(C)nc2=O)n2nc(C)c(C)c2n1 +Cc1cccc(C)c1OCCCNC(=O)C(C)(C)C#N +Cn1c(C2CC2)nc2cc(NS(=O)(=O)c3ccccc3)ccc21 +O=C(CNc1nccc(Oc2ccc(F)cc2)n1)NCc1ccco1 +CCCCNC(=O)c1cn(C)cc2c(=O)n(-c3ccccc3)nc1-2 +Cc1n[nH]c(C(C)NC(=O)CCc2cccs2)n1 +Cn1cc(C(=O)NCCNC(=O)c2cccc(F)c2)c2ccccc21 +Cc1oc(C(=O)N(C)CC(C)(C)O)cc1S(=O)(=O)N(C)C +CC(C)c1c(C(=O)N2CCCC2)cnn1-c1ccc(Cl)cc1 +O=C1OC(C(=O)N2CCc3ccccc3C2)Cc2ccccc21 +Cc1nc2c(c(C)nn2C)c(C)c1CCC(=O)N1CCCCCC1 +O=C(CCc1cccc(Br)c1)Nc1nccs1 +CCOC(=O)N1CCN(c2nn3cnnc3c3ccccc23)CC1 +CC(=O)N1CCc2ccc(NC(=O)c3ccc(C#N)cc3)cc21 +CCC(C)n1c(SCCC(N)=O)nnc1-c1ccccc1 +Cn1ccc(NC(=O)c2c3c(nc4ccccc24)CCC3)n1 +Cc1cc(C#N)n(Cc2ccc3c(c2)OCCO3)n1 +CS(=O)(=O)c1ccc(CNS(=O)(=O)c2cn[nH]c2)cc1 +CCCC1CN(C(=O)CCCOc2cccnc2)CCO1 +CC(=O)Nc1ccccc1OCc1nc(-c2cccs2)no1 +COC(=O)c1ccc(Cn2nnc(-c3ccc(C)cc3)n2)o1 +CCn1ccc(C(=O)N2CCCn3nc(-c4cccc(C)c4)cc3C2)n1 +Cc1nc2ccc(NC(=O)Cc3csc(C(C)C)n3)cc2s1 +CC1CCC(N(C(=O)Cn2cnc(C3CCC3)cc2=O)C2CC2)CC1 +COC(=O)c1ccn2nc(-c3ccc(N)cc3)nc2c1 +COC(=O)c1ccccc1N(C)c1ncnc(N)c1N +CCOC(=O)CCC(C)NC(=O)N1CCC2(CCCC2)C1 +Cc1ccc(OCC(=O)Nc2ncc(C)s2)c(Br)c1 +Cc1ccc(CNC(=O)Cn2nc(-c3ccc(F)cc3)oc2=O)cc1 +COCCNC(=O)N1CCC(C(=O)Nc2ccc(C)cn2)CC1 +CN(C(=O)c1cc(S(C)(=O)=O)ccc1Cl)c1ccccc1F +CS(=O)(=O)NCc1cccc(NC(=O)Cn2cccn2)c1 +CC(C)c1noc(NC(C(=O)N2CCOCC2)C(C)C)n1 +Cc1cccc(S(=O)(=O)CCCOc2cccnc2C)c1 +O=c1cc(C(F)(F)F)c2ccc(C(F)(F)F)cc2[nH]1 +Cc1cccc2c(=O)n(Cc3cccc4c3OCCO4)cnc12 +c1ccc(OCC2CC2)c(NCc2noc(-c3ccoc3)n2)c1 +CC(=O)c1cnc2nc(SCc3ccc(Cl)cc3)nn2c1C +CCCNC(=O)c1c(N)n(CCCOC)c2nc3ccccc3nc12 +CN1C(=O)NC(NC(=O)C2CC2)(C(F)(F)F)C1=O +CS(=O)(=O)N1CC2CC(CC(=O)N3CCCC3)OC2C1 +Cn1c(=O)ccn(CC(=O)Oc2ccc(Cl)cc2)c1=O +CCN(Cc1cccc(F)c1)C(=O)CNc1ccccc1F +N#CC1(NC(=O)CSc2ccccc2Cl)CCCC1 +Cc1cccc(NC(=O)Nc2cccc(CNC(=O)NCCO)c2)c1 +Nc1cc(OC(F)(F)F)ccc1Br +Cc1c(C(=O)NCC(=O)NCC2CCCCC2)cn2nc[nH]c(=O)c12 +CC1(NC(=O)c2cc(-n3cccn3)ccn2)Cc2ccccc2C1 +Cc1nc(C)c(CNC(C)C(O)c2ccc(F)cc2)s1 +CN(C)C(=O)c1cccnc1-c1ccc(C(N)=O)c(Cl)c1 +CC(=O)N(C)Cc1cccc(NC(=O)Nc2cccc(F)c2)c1 +Cc1c(C(=O)Nc2ccc3c(c2)CCCN3)cnn1C +Cc1cccc(NC(=O)Cn2nnc(-c3ccccc3Cl)n2)c1 +COC(=O)CNC(=O)c1sc2ncn(C)c(=O)c2c1C +CCCNc1cccc(C(=O)N2CCOCC2C)n1 +COc1ccccc1S(=O)(=O)NCC(C)(C)N1CCOCC1 +Cc1csc(-c2ccc(NC(=O)CCc3nccs3)cc2)n1 +Cc1cc(C)c2c(c1Br)OCC(=O)N2 +O=C(Nc1ccc(-c2c[nH]cn2)cc1)c1cnccn1 +CNC(=O)c1cccc(OC(=O)Cc2ccc(Cl)cc2)c1 +Cc1cnc(CN(Cc2ccccc2)CC(F)F)cn1 +CN(C)C(C(=O)NCCCn1cncn1)c1ccc(F)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)N1CC(C)(C)C1(C)C +CC(C)NS(=O)(=O)c1cccc(CNc2cccc(F)c2C#N)c1 +COCCn1nc(-c2ccc(OC)c(C)c2)cc(C#N)c1=O +O=S(=O)(NCc1ccco1)c1cccc(C(F)(F)F)c1 +CCCN(Cc1cnc2cc(C)ccn12)CC(F)F +CCN(CC)C(=O)CCC(=O)NCc1nc(C)c(C)o1 +COc1ccc(-c2ccnc3ccnn23)cc1OC +COc1ccccc1N1CCN(CC(O)COC2CCCC2)CC1 +COCCOc1cccc(NC(=O)c2cn(C)nc2C(C)(C)C)c1 +COc1cc(CNC(C)c2ccc(NC(=O)NC3CC3)cc2)ccn1 +COC1CCCN(C(=O)c2cc(-c3ccncc3)nc3ccccc23)C1 +COc1cc(C(=O)NCc2cccc(C)c2)nc2c(F)cc(F)cc12 +COC(=O)C1CCCCN1CCC(=O)OC(C)C +Cc1cccc(NC(=O)N(C)Cc2nc3ccccc3c(=O)[nH]2)c1 +Cc1cc(C)c2c(CC(=O)N3CCC(O)(CO)CC3)coc2c1C +O=C(COc1ccc2ccccc2c1)NCC#CCOc1cccnc1 +COc1cc(OC)cc(C(=O)N2CCc3ccc(N)cc32)c1 +Cc1cc(C)n(-c2ccc(CNC(=O)CCc3cccs3)cn2)n1 +CC(=O)NCCNC(=O)N1CCCC1c1ccc2c(c1)OCCO2 +FC(F)CN1CCN(Cc2cccc(-c3ccncc3)c2)CC1 +CC(=O)c1cccc(NC(=O)CN2C(=O)CCc3ccccc32)c1 +Cc1cc(C(C)NCC(O)c2cccs2)c(C)s1 +Cc1ccc(S(=O)(=O)NCCNC(=O)c2ccco2)cc1 +COc1ccc(C(=O)OCC(=O)Nc2nccs2)cc1F +CC(C)c1ncc(Cl)c(C(=O)NCC2CCCO2)n1 +CC(C)(C)CCNS(=O)(=O)CC12CCC(CC1=O)C2(C)C +CCc1nnc(-c2ccc(NC(=O)N(C)CCC#N)cc2)o1 +COCC(C)NC(=O)NC(C)c1c(C)noc1C +CCCC(=O)Nc1ccc(C(=O)N(CC)Cc2ccccc2)cc1 +CCOCC1CN(C(=O)Cc2cccs2)Cc2cn(CC)nc21 +CNc1snc(C)c1C(=O)NCc1coc(-c2cccs2)n1 +Cc1nn(C)c2nc(N3CCN(Cc4cccc(O)c4)CC3)sc12 +CC(=O)Nc1nc(C(=O)Nc2ccnc(C)c2)cs1 +CC(C)(C)c1nc(CNC(=O)Cn2cnnn2)cs1 +CNC(=O)NC(C)(C)C(=O)NCc1ccc(Cl)cc1Cl +Cc1cc(NC(=O)C2CCN(C(=O)c3cccc(Cl)c3)CC2)no1 +CCc1ccc(C2COCCN2Cc2c(CC)nn(C)c2OC)o1 +CCc1sc(C(=O)NCCc2cnc(C3CC3)nc2)cc1C +Cc1cccc(NS(=O)(=O)c2cc3[nH]c(=O)c(=O)[nH]c3cc2C)c1 +CNC(=O)c1ccc(CN2c3ccccc3CC2C(N)=O)cc1 +c1cc(CN(Cc2ccc(-n3ccnc3)nc2)C2CC2)ccn1 +Cc1ccc(SCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c(C)c1 +Cc1cccc2cc(-c3nc(-c4ccccn4)no3)c(=O)oc12 +CNC(=O)NCC(=O)NCC(C)Oc1ccc(C)cc1 +O=C(COc1ccccc1CO)Nc1ccccc1F +CCC(C)C(O)CNC(=O)NCC1CN2CCCCC2CO1 +CCc1nn(C)cc1CNC(=O)Nc1cnc(-c2ccccc2)nc1 +Cc1noc(C)c1CC(=O)N1CCCc2c(F)cc(F)cc21 +O=C(NCCNC(=O)c1cc2c(s1)SCC2)c1cccs1 +Cc1nnc(COc2ccc(NC(=O)c3cccnc3C)cc2)o1 +CCCc1cc(=O)c2cc(Cl)cc(Cl)c2[nH]1 +Cc1cccc(C)c1NC(=O)CSc1nccn1C +CCOC1C2CCC1N(S(=O)(=O)c1cccnc1)CCO2 +O=C(CCC1CCCO1)OCc1coc(-c2ccccc2)n1 +CCOc1cc(C#N)ccc1OC(=O)C(C)NC(=O)c1ccoc1 +CC(=O)c1c(SCCCOc2ccccc2)nc(=O)[nH]c1C +O=C(NC(Cc1ccccc1)C1CC1)c1ccncc1 +CC(C)(C)COC(=O)C1CCCN(C(=O)c2ccccc2)C1 +COCC(C)NC(=O)NCC(C)Oc1ccccc1 +O=C(NCC1(O)CCCCCC1)c1c[nH]nc1-c1ccccc1 +Cc1noc(C)c1C(C)C(=O)NC1CCCCC1OCCC(C)C +CC(C)(C)n1ncc2c(=O)n(CCC(=O)NCc3ccco3)cnc21 +CC(C)(C)OC(=O)N1CCCC2CC(O)CCC21 +O=C1Nc2ccc(-c3ccc(Cl)c(F)c3)cc2C1=O +Cc1ccc(C(=O)N2CCN(c3nnc4ccccn34)CC2)cc1C +Cc1ccoc1C(=O)N1CCC2(CC(Nc3ncccn3)CCO2)C1 +CC(c1ccc(F)cc1F)N1CCN(C2CCOC2=O)CC1 +Cc1ccccc1C1CC1C(=O)NCc1ccnc(OC2CCC2)c1 +COCCn1cc(NC(=O)c2ccc(-n3ccnn3)cc2)cn1 +NC(=O)CCN(C(=O)C1CC1c1ccc(F)cc1)c1ccc(F)cc1 +Cc1ccn2ncc(C(=O)Nc3ccc(F)cc3)c2c1 +Cn1cnnc1CNC(=O)c1ccc(F)cc1Br +OC1CCN(c2ncnc3c2nnn3Cc2ccccc2F)CC1 +CCOC(=O)NC1CCN(S(C)(=O)=O)CC1 +CC(Cc1c(F)cccc1F)NC(=O)c1cn[nH]c1 +Cc1cc(CNC(=O)NCCc2cccc(F)c2)no1 +Cc1ccc2cc(C(=O)Nc3ccn(Cc4ccncc4)n3)[nH]c2c1 +COC(=O)c1ccc(C2CC(=O)Nc3c2c(C)nn3C)cc1 +Cc1nc2ncnn2c(C)c1CCC(=O)OCC(C)C +CC(C)(C)C(O)CN1CCN(C(=O)CN2CCCS2(=O)=O)CC1 +CCCCn1c(N)c(C(=O)OCC)c2nc3ccccc3nc21 +Nc1nc2c(c(C(F)(F)F)n1)CC(=O)N2Cc1ccccc1 +COc1ccc(-c2c(C)sc3ncnc(NCC(C)O)c23)cc1 +Cc1ccc2nc3sc(C(=O)NCC4CCCO4)c(N)c3cc2c1 +Cc1ccc(NC(=O)OCc2ccccc2)cc1N1CCCCC1=O +O=C(NCCCOc1cccc2cccnc12)c1ccc(F)cc1 +O=C(NCc1noc(-c2ccsc2)n1)C1(c2ccc(F)cc2)CC1 +COc1ccc(NC(=O)c2ccc3c(c2)CCC(=O)N3)c(OC)c1 +CC(=O)NCCc1ccc(C(=O)COc2cccc(Cl)c2)s1 +CCNc1ncccc1CSc1nc(N)cc(=O)[nH]1 +CCOc1cccc(C2NC(=O)N(C)C(C)=C2C(=O)OC)c1 +CCCN(C)C(=O)c1cc(C)ccc1N1CCCC1=O +CCOc1ccc2c(c1)c(=O)ccn2CC(=O)OC +O=C(NCc1ccccc1)C1CCN(C(=O)c2ccco2)CC1 +COc1ccc(OC)c(N2CC(C(=O)Nc3ccccn3)CC2=O)c1 +CCCNC(=O)C(C)NC(=O)COc1ccccc1Cl +Cc1ccsc1C(=O)NC1CC(=O)N(CC(C)(C)C)C1 +O=C(CCc1nnc2ccc(NCc3ccco3)nn12)N1CCCC1 +CCN(C)C(=O)CCNS(=O)(=O)c1cccnc1 +O=C(NCCC1CCC1)N1CCC(OCc2ccccc2F)CC1 +CC(NCc1cccc2c1OCO2)C(=O)N1CCCCC1 +Cc1csc(CNC(=O)NCCc2cccc(C(=O)N(C)C)c2)n1 +N#Cc1c(F)cccc1N1CCN(C(=O)COC2CCCC2)CC1 +COC(=O)C(NC(=O)C1CC1c1ccccc1C(F)(F)F)C(C)C +CC(=O)Nc1cccc(CSc2nncn2C(C)C)c1 +CCCCS(=O)(=O)N1CCN(c2ncccc2C#N)CC1 +COC(=O)C1CN(Cc2ccn(-c3ccc(F)cc3)n2)CC(C)O1 +COc1cccc(CC2CN(C)c3cc(O)ccc3O2)c1 +COc1ccc(-c2cc3c4ccccc4nc(N)n3n2)cc1 +Cn1c(CNC(=O)c2cccs2)nnc1SCc1ccccc1 +COC(=O)c1nnn(-c2ccc(C)c(Cl)c2)c1C(=O)OC +CC(=O)N(C)c1ccc(NC(=O)COc2cc(C)ccc2C)cc1 +CCCn1c(SCc2cc(Cl)c3c(c2)OCCO3)n[nH]c1=O +CCC(C)C(O)CNC(=O)c1ccc(-n2ccnn2)cc1 +CCc1nn(CC(=O)NCC2CC2)c(=O)c2cc3ccsc3n12 +COC(=O)CC1CN(Cc2cnc(CC(C)C)s2)CCO1 +COc1ccc2occ(CC(=O)NCc3ccc(C)cc3)c2c1 +COc1cc(CNc2ccccc2Cl)ccc1O +Cc1cc(NC(=O)c2ccnc(SC(C)(C)C)c2)c[nH]c1=O +COc1ccc(-n2cnnc2SCCn2cccn2)cn1 +C#CCN(Cc1ccco1)C(=O)C(C)NS(C)(=O)=O +CSc1ccc(CN(C)C(=O)CC(C)C)cc1 +COc1cccc(CC(=O)N2CCN(C(C)c3ccccc3)CC2)c1 +Cc1ncc(Br)c(-c2ccccc2Cl)n1 +COc1ccc(C(=O)NCCc2cn3ccsc3n2)cc1 +NC(=O)c1nn(-c2ccc(OC(F)(F)F)cc2)c2c1CNCC2 +Cc1occc1C(=O)N1CCN(C(=O)c2c(F)cccc2F)CC1 +O=C(NCc1nc2ccccc2s1)c1cccc2ncccc12 +NC(=O)C1CN(C(=O)c2cccc(OC(F)F)c2)c2ccccc2O1 +Cc1ccc(CCC(=O)Nc2n[nH]c(-c3ccco3)n2)cc1 +Cc1csc(CNC(C)c2ccc(C)c(F)c2)n1 +CCC(=O)N1CCCN(Cc2cc(F)cc(C(F)(F)F)c2)CC1 +Cc1c(Br)cccc1CSc1n[nH]c(=O)n1C +CCc1ccc(-c2ncc3c(n2)CCCC3=O)s1 +CC(=O)C(C)n1c(CCNC(=O)c2ccco2)nc2ccccc21 +COc1cc2c(c(Cl)c1O)C(c1nc[nH]n1)NCC2 +Nn1c(SCc2c(F)cccc2F)nnc1-c1ccco1 +Nc1ncccc1Cn1c(CCO)nc2cccc(F)c21 +CC(NC(=O)Cc1ccc2c(c1)OCO2)C(=O)NCc1ccccc1 +CCS(=O)(=O)NCC(c1ccco1)S(=O)(=O)c1ccccc1 +CCCC(C(=O)OCC)N1CCN(C(=O)C2CCCO2)CC1 +Cn1cc(N2CCC3CN(C(=O)c4cccnc4)CC3C2=O)cn1 +CCOc1ccc(-c2cc(C(C)C)[nH]c(=O)c2C#N)cc1OC +Cc1noc(C)c1C(=O)Nc1ccc2c(c1)nc1n2CCCCC1 +O=S(=O)(NCc1ccc(F)cc1)c1ccc(-c2ccno2)s1 +Nc1cc(Cl)ccc1C(=O)Nc1cccc(F)c1 +COC(=O)CN(Cc1ccccc1C)C(=O)c1cnc2ccccc2n1 +COc1c(CNCC2CCN(C)c3ccccc32)c(C(C)C)nn1C +COc1ccc(-c2cc(C(=O)N3CCN(C)CC3C)no2)c(F)c1 +Cc1nc(COc2ccccc2Cl)[nH]c(=O)c1CCO +O=C(c1ccc2c(c1)OCO2)N1CCC2(CC1)Cc1ccccc1C2=O +CC(NC(=O)N1CCC(C(N)=O)C1)c1cc(F)c(Cl)cc1Cl +CCc1ccc(C(C)NC(=O)CN(C)CCC#N)cc1 +CCOc1ccccc1OCC(=O)NC(C)c1ccccc1 +Cc1nc(CNC(=O)Nc2cc(F)c(F)c(F)c2)c(C)s1 +CN(Cc1cc(C(C)(C)C)n[nH]1)c1nccc(N2CCCC(O)C2)n1 +O=C(NC1CC2C(=O)NCC(=O)N2C1)c1cncc(Cl)c1 +CC(C#N)CN(C)C(=O)c1cc2ccccc2s1 +CCOc1cc2c(cc1OC)CCNC2c1cc[nH]n1 +CCCNc1cnn(-c2nc3ccccc3[nH]2)c(=O)c1Cl +COc1ccc(C(=O)CCC(=O)N2CCC(C)CC2)cc1C +CCOC(=O)NCC(=O)N1CCN(S(C)(=O)=O)CC1 +COc1cccc(-c2nc(CSc3nc(C)n[nH]3)cs2)c1OC +COc1ccc(CC(=O)N2CCc3ccc(N)cc3C2)cc1 +COc1ccc(N(Cc2cccs2)C(=O)c2ccnnc2)cc1 +CC(C)c1nc2cc(-c3nc4ccc(N)cc4[nH]3)ccc2[nH]1 +Cc1[nH]c2ncnc(NC(=O)Cc3noc4ccccc34)c2c1C +COC(=O)c1[nH]c(C)c(C(=O)NC2c3ccccc3CC2O)c1C +CCCCN(C)C(=O)C(Cc1c[nH]c2ccccc12)NC(N)=O +COc1cccc(CN2CCc3nc(C(C)C)[nH]c(=O)c3CC2)c1F +CC(=O)Nc1ccc(CCC(O)c2ccccc2)cc1 +O=C(C1CCC1)N1CCN(c2ccc(Cl)cc2)CC1 +O=C(NCc1ccc(-c2cccnc2)cc1)c1cc2cccnn2c1 +NC(=O)c1ccc(-n2nnc(CO)c2-c2cccs2)cc1 +Cc1ccc(S(=O)(=O)N(C)c2ccccc2N)cc1 +O=C(NCCN1CCOCC1)c1c(Cl)cccc1Cl +CCC1Oc2cccc(N)c2N(CC(=O)OCC(C)C)C1=O +CNc1ccc(C)cc1C(=O)Nc1ccc(C)cn1 +CCOC(=O)N1CCC(NC(=O)NC(C)CC)CC1 +COc1ccc(CNC(=O)N2CCOC(C)(C)C2)cn1 +Nc1cccc(-c2nc3cc4c(cc3n2CCCO)OCCO4)c1 +CCSc1nc(=O)c2c(n1C)NC(=O)CC2c1ccc(CC)cc1 +CCc1nc2cc(NC(=O)CC3CCCO3)ccc2o1 +Cn1c(-c2ccc(Cl)cc2)ccc(CC#N)c1=O +CC(=O)Nc1cc(S(=O)(=O)Nc2cnn(C)c2)ccc1F +CCCNC(=O)c1cnc2c(ccn2C2CCCCC2)c1 +Cc1nc(CNC(=O)Cc2cnc3c(C)cccn23)nc2c1CCCC2 +Cc1cc(C(=O)Nc2ccc3ccccc3n2)c2cnn(C(C)C)c2n1 +Cc1cc(C(=O)OCc2cc(-c3ccc(F)cc3)on2)no1 +Cn1cc(C(=O)Nc2nc3c(s2)CCC3)ccc1=O +COC(=O)c1cc(C(=O)OC)cc(-n2nnc(CO)c2C)c1 +CC(C)CN1C(=O)COC2CN(C(=O)N(C)C)CC21 +O=C(Cn1cc(-c2ccc(F)cc2)oc1=O)NCCc1ccccn1 +CCc1cc(C(=O)NCc2ccc(OC)c(C(=O)OC)c2)[nH]n1 +O=C(NCc1ccco1)C1CC2OCCC2N(c2ncccn2)C1 +COc1cnc(C(=O)N2CCC(O)(c3ccc(C)cn3)CC2)cc1O +COc1ccccc1CCNC(=O)c1cncc(Br)c1 +NC(=O)C1CCN(C(=O)NCCOc2ccc(F)cc2)CC1 +Nc1c(NC2CCCC2)ncnc1Sc1ccccc1 +CNc1ccnc(-c2cc(Br)cs2)n1 +Cc1cc(C)n(CC(=O)Nc2cc(N)ccc2F)n1 +CCCCn1nc(C2CC2)nc1-c1cnn2cc(C)cnc12 +Cc1cc(C)cc(NC(=O)c2cc3c(C)nn(C)c3nc2N)c1 +CCCCOc1ccccc1NC(=O)c1ccc(=O)[nH]c1 +COCCn1nc(-c2cccc(OC)c2)cc(C(C)=O)c1=O +Cc1ccc(C(=O)CCS(=O)(=O)c2ccc(F)cc2)cc1 +Cc1ccc(CNC(=O)N2CCC(NS(C)(=O)=O)CC2)cc1F +CCc1nc2ccccc2c(=O)n1CC(=O)Nc1ccc(F)cc1C +CCN(C(C)=O)c1nc(CNCC(=O)OC)cs1 +O=C1OCc2nc3c(c(-c4ccccc4)c21)C(=O)OC3 +Cc1csc(NC(=O)c2ccc3c(=O)n4c(nc3c2)CCC4)n1 +C#CCN1CCN(C(=O)NCCc2ccncc2C)CC1 +CCNc1nnc(SCC(=O)C(C#N)c2nc(C)cs2)s1 +Cc1ccc2nc(NCc3ccncc3)c3nnnn3c2c1 +CC(CC(=O)NC1CCN(C)C1=O)NC(=O)c1ccccc1 +CCC(C)NC(=O)Nc1ccc(F)c(C(N)=O)c1 +CCOC(=O)c1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)cc1 +Cc1cccc(C)c1NC(=O)c1ccccc1NC(=O)c1cccnc1 +COCc1noc(C2COc3ccc(F)cc3C2)n1 +Cc1ccc(C)c(C(O)CNC(=O)Cc2ccc(F)cc2)c1 +CCC1(C)Cc2ccccc2-c2nc(SCC(N)=O)[nH]c(=O)c21 +CC1(CNC(=O)c2cnc(C3CCCO3)s2)CCCC1 +Cc1cccc(S(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1 +CNc1ncc(C(=O)NC(C)COc2ccccc2OC)cn1 +CS(=O)(=O)N1CCC2OC(COCc3cccnc3)CCC21 +COc1ccc(-c2nnn(CC(=O)NCCc3ccccc3)n2)cc1 +CCn1cc(C#N)c(=O)n(Cc2ccc(C#N)cc2)c1=O +COCC(C)(NC(=O)c1ccc(Br)cc1Cl)C(N)=O +CC1CCN(C(=O)NCCNC(=O)OC(C)(C)C)C(C)C1 +COC(=O)c1ccc(NC(=O)CSc2cc(C)[nH]c(=O)n2)cc1 +CN(CC(=O)Nc1ccccc1-n1cccn1)C(=O)c1ccccc1 +Cn1c(NC(=O)c2n[nH]c(=O)c3ccccc23)nc2ccccc21 +COCCNC(=O)c1cnc2sc(C)c(C)n2c1=O +Cc1n[nH]c(C)c1CNc1nccc(OCc2ccccc2)n1 +O=C(Cn1cnc2cc(F)ccc2c1=O)NCCc1ccccc1 +Oc1ccc(C2CCN(c3nnnn3-c3ccccc3)CC2)cc1 +Cc1ccn2c(=NC(=O)C3(C)CC3(Cl)Cl)[nH]nc2c1 +N#Cc1nnn(-c2ccc(F)cc2)c1C(Cl)(Cl)Cl +O=C(Cc1ccsc1)Nc1ccccc1C(=O)NCc1ccco1 +Cc1nn(C)c(NC(=O)c2cnc(Cc3ccccc3)s2)c1C +CCCN(CCC)c1nc(C)cc(C(=O)OC)n1 +CN(C)S(=O)(=O)NC(CCO)c1cccs1 +O=C(NCC1CCCO1)c1ccccc1SCc1ccccc1 +COc1ccc(NC(=O)CSc2ncn[nH]2)cc1OC +COc1ccc(-c2nc(C)c(CCO)s2)c(F)c1 +O=C(Nc1nc(-c2ccco2)cs1)c1cscn1 +Cc1nn(C)c2ncc(S(=O)(=O)NCCc3ccccc3)cc12 +O=C(NCCCOCC1CC1)c1cccc2[nH]ccc12 +CN(Cc1ccc(F)c(C(F)(F)F)c1)CC(F)F +CC1(O)CCN(c2ncccn2)CC1Cc1ccccc1 +C=CCNC(=O)c1ccc(NC(=O)NCCc2cccs2)cc1 +NC(=O)c1cccc(OC(=O)c2sccc2Br)c1 +Cc1cc(OCCC(=O)NC(C)(C)CO)ccc1Cl +Nc1nc2scc(-c3ccc4c(c3)OCO4)n2n1 +CNC(=O)C(C)NC(=O)c1ccc(OC2CCCCC2)cc1 +Cc1csc2ncn(CCN3CCCC3=O)c(=O)c12 +CCc1nc(CC(=O)Nc2ccc(C)cc2O)cs1 +CCCC(=O)N1CCCC1C(=O)OCC1CC=CCC1C +O=C(Nc1cccc(NC(=O)C2CC2)c1)Nc1cnn(CC(F)F)c1 +CCn1nnc2cc(C(=O)NCc3ccc(C)c(F)c3)ccc21 +CC1CCN(S(=O)(=O)c2ccc(F)c(S(C)(=O)=O)c2)C(C)C1 +Cc1ccnc2nc(C(=O)N3CCc4ccccc4C3)nn12 +Cn1ncc(C#N)c1NC(=O)Cc1ccc(Cl)cc1 +O=C1NCCCc2[nH]c(Cc3ccccc3C(F)(F)F)nc21 +COCCN(Cc1ccccc1)C(=O)c1cc(Cl)ccc1OC +CC(CO)(Cc1ccc2c(c1)OCCO2)c1ccccc1 +[H]N=c1n(Cc2ccccc2)c2ccccc2n1CC(O)c1ccco1 +Fc1ccc(C2(c3nnc(C4CC4)o3)CCOCC2)cc1 +Cn1cc(CCNc2nncc(-c3ccccc3F)n2)cn1 +Cc1cc(C(=O)Nc2nc(C3CC3)cs2)c2c(=O)[nH]n(C)c2n1 +Cc1cc(C)c2cc3c(N)c(C(N)=O)sc3nc2c1 +CC(C)CCOCCN1CCN(c2ccc(O)cc2)CC1 +COc1cccc(OCC(=O)OC2CCCCC2OC)c1 +COC(=O)c1ccc(COc2ncnc3sccc23)cc1 +COc1cc(CCNC(=O)N2CCCCC2c2cn[nH]c2)ccc1F +c1sc(N2CCOCC2)nc1N1CCOCC1 +CC(=O)N1CN(CC2CCCO2)Cc2c1sc1c2CCCC1 +O=C(NCCOc1ccc2c(c1)OCO2)c1ccccc1F +COc1ccccc1CNc1cccc2cnccc12 +CCCCCCNc1ncnc2c1[nH]c1ccc(F)cc12 +O=C(CSc1nnc2n1CCCCC2)NCC(=O)N1CCCC1 +Cc1cc(N)cc(S(=O)(=O)NCCc2nccs2)c1 +CCOc1ccc(C(=O)N2CCC(NC(=O)N(C)C(C)C)CC2)cc1 +Cc1ccc(C(=O)Nc2cccc(C(=O)N(C)C)c2)cn1 +O=C(Nc1ccncc1)c1ncoc1-c1ccccc1Cl +C#CCNS(=O)(=O)c1ccc2c(c1)CCCN2 +CCCNc1nc2cc(OC)c(C(=O)OC)cc2s1 +O=C(Cn1ccc2ccccc21)N1CC(c2nc(-c3ccco3)no2)C1 +CCCn1cc(C(=O)Nc2ccccc2SC)c2cccnc21 +COc1ccc(Br)cc1S(=O)(=O)Nc1ccn(C)n1 +COC(=O)CC1CCN(c2ccc(C#N)cc2C(F)(F)F)CC1 +Nc1cc(F)ccc1NC(=O)CCOC1CCCC1 +O=C(NCCOc1cccnc1)c1cc(F)ccc1Br +CCN(CC(=O)NC(C)(C)C)c1ncnc2c1cnn2C +Cc1cc(O)ccc1NC(=O)Cc1cccc(Cl)c1 +COc1ccc(N)cc1NC(=O)c1cccc(OCC(C)C)c1 +O=C1C(NCc2cccc3c2OCCO3)CCN1Cc1ccccc1 +CCCCN1CC(C(=O)Nc2nnc(C(C)(C)C)s2)CC1=O +CC(NC(=O)C1CNc2ccccc2O1)c1ccccc1 +O=C(Cc1nc(CO)cs1)Nc1ccc(Cl)c(Cl)c1 +COc1ccc(CNC(=O)Nc2nnc(-c3ccsc3)o2)cc1 +Cc1ccc(CC(=O)N(Cc2ccccn2)C2CC2)cn1 +COc1ccc(CNC(=O)c2ccnc(OC3CCC3)c2)cn1 +Cn1cc(C(=O)Nc2ccc3c(c2)CCC3)ccc1=O +CCCS(=O)(=O)N1CCCC(C(=O)c2ccccc2OC)C1 +CCC(OC1CCCC(C)C1)C(=O)NCc1n[nH]c(C)n1 +COC(=O)c1ccc(C(=O)NCc2cccc(OC)c2)s1 +Cc1cc(C)c(NCCC(O)c2cccs2)c(C)c1 +COc1cccc2c1OCC(CNC(=O)c1c[nH]c(C)cc1=O)C2 +Cc1ccc(C(=O)N2CCCC(NC(=O)C(C)C)C2)c(O)c1 +COc1ccc(F)cc1NC(=O)C(NS(C)(=O)=O)C(C)(C)C +Nc1nonc1-c1noc(-c2cccc(Br)c2)n1 +NC(=O)Nc1cccc(OCCc2ccccc2)c1 +CCOC(=O)C(C)N1CCC(NC(=O)C(C)C)CC1 +O=C(CN1CCN(c2ccc(O)cc2)CC1)Nc1nncs1 +Cc1csc(CNC(=O)c2nc(C)n(-c3ccc(F)cc3)n2)n1 +COc1cccc(C(=O)Nc2ccc(Br)c(C)n2)c1F +Cc1cccc(C(=O)Nc2nc3cc4c(cc3s2)OCCCO4)n1 +CC(C)(O)c1sc(N2CCCC2)nc1C1CC1 +CC(NC(=O)Nc1ccc(OCC(N)=O)cc1)c1ccccc1 +O=C(Cn1nnc(-c2ccccc2)n1)Nc1c(Cl)cccc1Cl +O=S(=O)(NCC1(O)CCCC1)c1cccnc1 +CCOC(=O)c1c(OCCO)nn(-c2ccccc2)c1N +COCCCCCNC(=O)c1c(C)c(C)nn(C)c1=O +Nc1ccc(SCc2nc(-c3ccco3)no2)cc1 +OCc1ccc(OC(F)(F)C(F)C(F)(F)F)cc1 +N#Cc1cccnc1SCc1ccc(F)c(F)c1 +CC(C)(C)n1nc(C(=O)Nc2ccnc3ccnn23)cc1C1CC1 +CCCNC(=O)c1ccc(-c2ccc(C)cc2)nc1N +CC(=O)Nc1cccc(NC(=O)c2cc3ccccc3o2)c1 +CCCNc1nc2c(c(=O)[nH]c(=O)n2C)n1CCC(C)C +COc1cccc(NC2OC(=O)c3ccccc32)c1 +Cc1cccnc1NC(=O)c1cc2c(s1)CCCC2 +CS(=O)(=O)NCc1nc(-c2cccc(Cl)c2)no1 +COC(=O)c1ccc(CSc2nnnn2-c2cccc(C)c2)o1 +Cc1cc(C(C)C(=O)N2CCC(c3nncn3C)CC2)c(C)o1 +CCCCCCNC(=O)c1cnc(N2CCOCC2)nc1N +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NCC#Cc1ccccc1 +O=C(c1ccc(F)c(F)c1)N1CCN(C(=O)N2CCOCC2)CC1 +O=C(CC1CC1)N1CCC(Oc2ccccn2)C2OCCC21 +O=C(CNC(=O)c1ccoc1)NCCNC(=O)C1CC1 +CC(=O)Nc1ccc(Cl)c(NCc2cccc(C)c2)c1 +Cc1c(C(=O)NCCNC(=O)C2CCCCC2)cn2nc[nH]c(=O)c12 +Cc1cccc(NC(=O)Cn2nc(-c3ccc(F)cc3)ccc2=O)c1 +CC(c1ccc(Cl)cc1)N(C(=O)c1ccc(C(N)=O)cn1)C1CC1 +COC(=O)c1cnc(NC(=O)CCc2cc(C(C)=O)c(C)o2)s1 +Cc1nn(C)c(=O)c(C(=O)N2CCC(c3cccc(F)c3)C2)c1C +CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc1ccncc1 +COCc1nnc(NC(=O)c2csc(NC3CC3)n2)s1 +O=C(CSc1ccccc1)Nc1ccn(-c2ccc(F)cc2F)n1 +C=C(C)CN(CC)C(=O)C1CC(=O)N(C(C)C)C1 +COC(=O)c1ccc(Cn2cc(Br)c(OC)cc2=O)o1 +COc1ccccc1Nc1nc2nccc(-c3ccncc3)c2c(=O)[nH]1 +CSc1nsc(NC(=O)C2CCOCC2)n1 +CCOc1ccc(N2CC(C(=O)NC(C)C)CC2=O)cc1 +CCN(CC)c1nc(-c2cnn(CC)c2C)cc(C(F)F)n1 +Cc1nc(=O)c2nnn(CC3CCCN3C(=O)C(C)C)c2[nH]1 +CCOc1ccc(N(CCC#N)C(=O)c2ccc(F)cn2)cc1 +O=C(CC1NC(=O)c2ccccc2N=C1O)NCCC1=CCCCC1 +COc1cccc(-c2cc(C(=O)Nc3ccc(F)cc3)n[nH]2)c1 +C#Cc1cccc(NCc2cccc3c2OCO3)c1 +CNC(=O)C1CCCN1C(=O)c1ccccc1OC(F)F +O=C(c1c[nH]cn1)N1CCCC2(CC(Nc3ncccc3F)CO2)C1 +CC(NC(N)=O)C(=O)Nc1nnc(C(C)(C)C)s1 +O=C(CCCN1CCOC1=O)Nc1ccc(-n2cccn2)cc1 +O=C(NCC1CCN(C(=O)c2ccoc2)CC1)c1ccoc1 +O=S1(=O)C=C(N2CCOCC2)c2ccccc21 +CN1CCN(C(=O)c2ccc(=O)n(C)c2)c2ccccc21 +COc1cccc(-c2cc(CO)nn2CCCC#N)c1 +c1ccc2c(CC3CN(Cc4nccs4)CCO3)cccc2c1 +CC(C)NC(=O)CSc1ccc(-c2ccncc2)nn1 +CC(C)N(C)C(=O)C1CC(=O)N(Cc2ccccc2F)C1 +COc1ccc(Cl)cc1S(=O)(=O)Nc1ccccn1 +COC(C)C(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 +Cc1cccc(C(=O)NCc2ccc(F)cc2)c1N +CCOCC1CCN(C(=O)C2CC(=O)N(C)C2c2cccnc2)CC1 +CC(=O)OC(OC(C)=O)(c1ccccc1)c1ncccn1 +CC(O)CCN(C)C(=O)NCc1ccc(Br)cc1Cl +O=C(C1CC=CCC1)N1CCC(S(=O)(=O)c2ccccc2)C1 +CCn1c(SCc2ccc(C)cc2)nc2c1c(=O)n(C)c(=O)n2C +COc1ccc(C2CC(=O)c3cc(Cl)ccc3O2)cc1OC +COc1ccc(CNc2cccc3cccnc23)cc1F +CC(c1ccccc1)N(C)C(=O)c1nn(C)c(=O)c2ccccc12 +CC1CCCCC1NC(=O)COc1ccc(F)c(F)c1 +COc1ccc(OC)c(CCC(=O)N2CCC(O)CC2)c1 +CCn1c(C)cc(C(=O)COc2ccc(Cl)cc2C(N)=O)c1C +CCCc1n[nH]cc1C(=O)N1CC(NC(C)=O)C(C(C)C)C1 +Cc1cc(C)n(CCCNC(=O)c2cccnc2)n1 +CC(=O)Nc1ccc(NC(=O)CSc2ncn[nH]2)cc1 +CN(CC1CCN(C(=O)OC(C)(C)C)C1)C(=O)c1ccsc1 +CCCOCC(=O)Nc1cc(OC)ccc1Cl +Cn1nccc1C(=O)NCC12CC3CC(CC(C3)C1)C2 +O=C(CS(=O)(=O)c1ccc(O)cc1)NCC1(c2ccccc2)CC1 +COc1cc(NC(=O)Cc2cccc(C)c2)cc(OC)c1OC +Nc1c(-c2ccccc2F)noc1C(=O)Nc1nccs1 +COc1ccc(NC(=O)c2cc(-c3ccc(F)cc3)[nH]n2)cc1OC +CC(Cn1cncn1)n1cnc2sc3c(c2c1=O)CCCCC3 +Cc1n[nH]cc1CN(C)C1CCCN(c2ccccc2)C1 +COC(=O)NCC(=O)N(Cc1cccc(F)c1)C1CC1 +CCn1cc(C#N)c(=O)n(CC(=O)NCCc2cccs2)c1=O +COc1ccc2nnc(CCC(=O)Nc3nnc(C)s3)n2n1 +CC(C)OCCCNC(=O)c1csc(-c2cnccn2)n1 +CCN(C1CC1)S(=O)(=O)c1ccc2c(c1)OCCO2 +CCOC(=O)CCC(=O)c1ccc(Cl)c(F)c1 +CN(Cc1ccc(F)cc1F)C(=O)c1cc(C2CC2)[nH]n1 +CC(C)OC(=O)CCNC(=O)NC1CC1c1cccc(Cl)c1 +C=CCn1c(SC(C)C(N)=O)nnc1-c1cccc(C)c1 +COCc1cncc2c1CCN(C(=O)c1ccoc1)C2 +CC(C)NC(=O)CCS(=O)(=O)c1ccc(O)cc1 +Cc1nc2ccc(NC(=O)C(C)Oc3ccccc3)cc2s1 +CC(OC(=O)c1ccc2c(c1)COC2)c1nnc(-c2cccs2)o1 +CCSc1ccc(C(=O)Nc2nc(C)c(C(C)=O)s2)cc1 +CC1CCC(N(C)C(=O)C2CC2(Cl)Cl)CC1 +CSc1nnc(Cn2nc(-c3ccco3)oc2=O)s1 +Cc1ccccc1NC(=O)C(C)NC(=O)C1CCCCC1 +COc1ccc(C(C#N)NC(=O)c2ccoc2)c(OC)c1 +CCNC(C)(C#N)CCCSc1nccc(C)n1 +CN(Cc1cc2ccccc2o1)C(=O)Nc1ccc(C(N)=O)c(F)c1 +NC(=O)COc1ccc(Cl)cc1C1CCCCC1 +CCc1n[nH]c(SCC(=O)Nc2cccc(C(F)(F)F)c2)n1 +Nc1nnc(SCc2ccc(Cl)cc2Cl)n1C1CC1 +CCOC(=O)CN(CC)C(=O)c1ccc(-n2cccn2)cc1 +O=S(=O)(N=S(=O)(c1ccccc1)C(F)F)c1ccccc1 +Cc1c(-c2ccc(OCC(C)C)cc2)n[nH]c1CO +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)OCC2CC=CCC2)c1 +CCc1cc(C(=O)NC(COC)C(N)=O)sc1C +CN(Cc1ccco1)C(=O)c1ccccc1C(=O)c1ccccc1 +Cc1c(Cl)cccc1-n1nc(CC(N)=O)nc1C1CCC1 +Cc1nc(C)n(CC2CN(C(C)c3nc(C4CC4)no3)CCO2)n1 +CC(C)c1ccc(NS(=O)(=O)c2ccc(N)cc2)cc1 +O=c1[nH]c2ccccc2cc1CNc1cc(Cl)ccc1O +COc1ccc(S(=O)(=O)Nc2cn[nH]c2)c(N)c1 +CCOC(=O)C(C)n1c(=O)oc(=O)c2cc(C)ccc21 +CN(Cc1ccccc1)C(=O)CNS(=O)(=O)c1cccs1 +N#Cc1cccc(OCC(=O)NCCOc2ccc(Cl)cc2)c1 +Cc1cccc(N2CCN(C(=O)c3ccc(=O)[nH]c3)CC2)c1 +CCC(C(=O)OC)N(C(=O)c1ccoc1)c1ccccc1 +O=C(Nc1ccccc1N1CCCCC1)C1CCCO1 +Cc1csc(C(=O)N2CCC(Oc3cccnc3)CC2)c1 +CCOc1cc(C#N)ccc1OC(=O)CCc1ccc(C#N)cc1 +NC(=O)c1ccc(NC(=O)Nc2ccccc2OCC2CC2)cc1F +CCC(=O)N1CCCN(C(=O)c2cc(Br)cn2C)CC1 +COc1cccc(C(=O)NCC#CCOc2cccnc2)c1OC +CC(COc1ccc(F)cc1)NC(=O)C(C)c1ccsc1 +Cc1csc(N(C(=O)CN(C)S(C)(=O)=O)c2ccccc2)n1 +CCOC(=O)CN(CC)C(=O)c1cnc2sccn2c1=O +O=C(c1ccc2ncnc(N3CCCC3)c2c1)N1CCOCC1 +CCC1CCCN(C(=O)c2cnc(C3CCCO3)s2)C1 +CCN(Cc1cc(C#N)cs1)Cc1c(F)cccc1F +C=CCc1ccccc1OC(=O)C1CCN(S(=O)(=O)CC)CC1 +CCOC(=O)CN(C(=O)CC1CC2CCC1C2)C(C)C +O=C(COC(=O)Cc1ccccc1F)Nc1ccc2c(c1)OCO2 +CC(=O)N1CCCC(C(=O)NCC(=O)C(C)(C)C)C1 +O=S(=O)(c1ccccc1)N1CCn2cc(-c3ccccc3)nc2C1 +COc1ccc(CNC(=O)c2cnc(N(C)C)nc2)c(OC)c1 +COc1ccccc1CNC(=O)c1cn(Cc2ccccc2)nn1 +Nc1c(-c2cc(F)ccc2F)nnn1-c1cccc(O)c1 +CCOC(C)c1noc(CNC(=O)c2cnc(C(C)C)s2)n1 +COCc1nc2cc(OC)c(OC)cc2n1CCCO +CN(C(=O)c1ccnc(OC2CCC2)c1)c1ccccc1F +O=C(CNC(=O)NCc1ccccc1)NC(C1CC1)C1CC1 +N#Cc1ccc(OCC(=O)NCCCN2CCOCC2)cc1 +COc1ccc(OC)c(NC(=O)C(C)Oc2cccc(F)c2)c1 +CC1CC(C)CN(C(=O)CNC(=O)c2ccc(Cl)cc2Cl)C1 +Oc1ccc(-n2nnnc2SCC2CCOCO2)cc1 +COCc1ccccc1NC(=O)CCC(=O)c1ccc(F)c(F)c1 +CCOc1ccc(C(=O)NC2CCCC(C)C2)cc1OCC +CC(NCC(CCO)c1ccccc1)c1ccco1 +CC(C)OC(=O)c1nnc2sc(-c3cccc(F)c3)nn12 +O=C(Nc1ccc(F)cc1)c1c[nH]c2cc(Cl)ccc2c1=O +COCCCN(C)C(=O)c1ccc(C(N)=O)cc1 +COc1ccnc(NC(=O)C(C)(C)CC(C)C)c1 +N#Cc1ccc(OC(=O)C2CCOc3ccccc32)c(Cl)c1 +CC(C)NC(=O)c1ccc(-c2ccccn2)nc1N +COc1cccc(C(=O)CN2C(=O)CN(C)C(=O)c3ccccc32)c1 +COCc1ccc(CNC(=O)c2ccc(C(=O)N(C)C)cc2)cc1 +COc1ccc2c(c1)nc(C#N)n2Cc1cccc(C#N)c1 +CN(C(=O)c1ccc(N2CCNC2=O)cc1)c1nccs1 +Cc1noc(CCCC(=O)Nc2nc3c(s2)CCCCC3)n1 +COC(=O)Cc1ccc2oc(-c3cccnc3)nc2c1 +CCC(C)(C)NC(=O)C1CCN(S(=O)(=O)c2ccccc2)CC1 +CC#CCSc1nnnn1Cc1cccs1 +C=CCN(CC=C)S(=O)(=O)c1ccc(OC)c(Br)c1 +CCOc1ccc(S(=O)(=O)NC2CCCC2)cc1N +CC(NC(=O)c1ccccc1)C(=O)NCC1CN2CCCCC2CO1 +Cc1cc(Br)cnc1N1CCOC(C2CCCO2)C1 +CCOC1CC(N(C)S(N)(=O)=O)C12CCCC2 +COc1ccc(F)cc1CS(=O)(=O)c1ccc(O)cc1 +CS(=O)(=O)c1ccc(SCC(=O)NCc2ccccc2)cc1 +Cc1nc(C)c(C(=O)Nc2ccc(Cl)cc2O)o1 +CC1Oc2ccc(NC(=O)NC(C)C(C)C)cc2NC1=O +Cc1ccccc1S(=O)(=O)Nc1ccccc1F +c1cc(NCc2cccc3[nH]ccc23)cc(N2CCOCC2)c1 +CCOC(=O)C1CCCN(C(=O)CCc2ccc(F)c(F)c2)C1 +CN1CCc2nc(NC(=O)c3ccccc3)sc2C1 +CCC(=O)Nc1ccc(NC(=O)NCCc2nc(C(C)C)no2)cc1 +CCCOc1ccc(Cl)cc1C(=O)CCOC +CCCC(=O)Nc1cc(-c2cn3nc(OC)ccc3n2)ccc1F +COc1cccc(NCc2cc(OC)c(OC)cc2OC)c1 +N#CCOc1cccc(NC(=O)NCc2ccccn2)c1 +CC(Sc1nnc2sc3ccccc3n12)C(=O)N1CCCC1 +Cc1cccc(CC(=O)Oc2cccc(C(=O)NCC(N)=O)c2)c1 +CC(C)N(CC(N)=O)S(=O)(=O)c1cccs1 +c1cc(C2CC2)n2cnc(C3CN(Cc4ccncc4)CCO3)c2c1 +CCC1NCCc2cc(OC)c(O)c(Br)c21 +CCC(CC)C(=O)N1CCCCC1CC(=O)OC +Cc1ccc(C)c(NCC(=O)Nc2ccc3c(c2)OCCO3)c1 +Cc1cc(C(=O)NCc2ccc(N3CCCCC3=O)cc2)no1 +CCCn1cc(NC(=O)c2cc(C)no2)ccc1=O +CC(Cn1cncn1)NS(=O)(=O)c1c(Cl)cccc1Cl +CN(C)C(=O)C1(CNC(=O)c2csc(-c3ccoc3)n2)CCCC1 +Cn1c(=O)c2cc(NC(=O)NCc3ccco3)cnc2n(C)c1=O +N#CCCN(Cc1ccccn1)C(=O)c1n[nH]c2ccccc12 +CCNc1nc(-c2scnc2C2CC2)cs1 +NC(=O)c1cnc(NC(=O)c2cccc(CN3CCCC3=O)c2)s1 +CS(=O)(=O)N1CCC(Oc2ncccc2Cl)CC1 +Cc1cc(C)nc(SCC(=O)Nc2cccc(O)c2)n1 +CCOc1cccc(NC(=O)NC(CC)CO)c1 +Cc1nc(CNC(=O)CNC(=O)COc2ccccc2)c(C)s1 +c1cncc(-c2nnn(-c3ncnc4sc5c(c34)CCCC5)n2)c1 +COc1ccccc1C(=O)Nc1c(C)nc(N2CCCC2)nc1C +Cc1ccc(-c2noc(CCCC(=O)NCC3CCCO3)n2)cc1 +Cc1cccc(Nc2ccc(S(C)(=O)=O)cc2N)c1 +O=C(Cn1nnc2ccccc2c1=O)Nc1nnc(C2CCC2)s1 +Cc1ccc(S(=O)(=O)NC2CCCc3occc32)s1 +CCc1ccc(CNc2ccc(-n3cncn3)c(F)c2)o1 +CCN1C(=O)C(C)c2cc(C(O)C3CCCO3)ccc21 +CC(C)C(CNC(=O)c1ccccc1F)N1CCOCC1 +COc1ccc(-c2nnc(COc3ccc(C#N)cc3OC)o2)cc1 +CC(=O)N1CCC(NC(=O)CNc2cccc(C)c2)CC1 +COCCN1CC(C(=O)N(C)c2cccc3ncccc23)CC1=O +CCn1nc(C)c(NC(=O)c2nn(C)c3ccc(C)cc3c2=O)c1C +O=C(Nc1ccccn1)c1ccc2c(=O)n3c(nc2c1)CCC3 +Cc1ccc(CN2CC(C(=O)N3CCc4ccccc43)CC2=O)cc1 +COCCN(CCC#N)C(=O)c1cccc(-n2cccn2)n1 +CC(Oc1ccccc1C(F)(F)F)C(=O)NC1CC(=O)N(C)C1 +CCOC(=O)C1=C(C)N(C)C(=O)NC1c1cccc(C#N)c1 +O=C(NCc1ccccc1)c1cnn2c3c(cnc12)CCCC3 +C=CCN(C(=O)c1ccc(N2CCCC2)nc1)C1CCCC1 +CC(C)C(NC(=O)c1ccnc2[nH]ccc12)C(=O)NC1CCCC1 +O=C(Cn1c(C2CC2)nc2ccccc21)N1CCc2cc(F)ccc2C1 +O=C(NCCCNC(=O)c1ccc(Cl)cn1)c1cccc(O)c1 +CC1Oc2cc(O)ccc2N(Cc2cccc(Cl)c2)C1=O +CC(=O)NCC(=O)N1CCC(OCc2ccccc2C)CC1 +CC(=O)N1CCC(c2cccc(-c3ccccc3Cl)n2)CC1 +CCOC(=O)c1c[nH]c2c(C)cccc2c1=NCCCO +O=C(NCC(O)c1cccc(F)c1)Nc1cccnc1 +COc1ccccc1CNc1nc(NCCO)c2nccnc2n1 +O=C(c1ccco1)N1CCN(c2ncnc3[nH]cnc23)CC1 +O=C(CCn1c(=O)sc2ccccc21)NCc1ccccc1 +CC(c1ccc(F)cc1)N(C)C(=O)Cn1nc2c(cc1=O)CCCC2 +CN(CCOc1ccccc1)S(=O)(=O)c1cccc(C(N)=O)c1 +C=CCNC(=O)c1cc(NC(=O)c2ccccc2)n(C)n1 +O=C(c1ccccc1)c1cn[nH]c1-c1ccccc1O +CCSc1nnc(NC(=O)Oc2ccccc2)s1 +CC1CN(C(=O)Cn2cnc(C#N)c2C#N)CC(C)O1 +O=C(Nc1cccnn1)NC1C2CCOC2C12CCCC2 +COCCNC(=O)N1CC=C(c2ccc(F)cc2)CC1 +COc1ccc(-c2noc(CCn3ccccc3=O)n2)cn1 +CCC1CN(S(=O)(=O)CCCC(=O)OC)CCO1 +CCCCSc1nc(N)cc(N(C)CCO)n1 +Cc1cc(C(=O)N2CCC3CC(C)OC3C2)no1 +CC(C)NC(=O)C1CCCN(c2nc3ccc(F)cc3s2)C1 +O=C(NCCCO)c1cnn(-c2ccccc2F)c1-n1cccc1 +Cc1ccc(OCc2ccc(F)cc2Br)c(CO)n1 +Cc1ccc(S(=O)(=O)N(C)C(C)(C)C#N)cc1 +O=C(Nc1cc(F)ccc1O)c1scnc1C1CC1 +Cc1nn(C)c(C)c1S(=O)(=O)NC(C)(C)C#N +CC(=O)Nc1ccc(OCc2noc(C(=O)NC3CC3)n2)cc1 +Cc1ccccc1OCC#CCNC(=O)c1cc(-c2ccco2)n[nH]1 +CCN(CCCNC(=O)Nc1ccc(F)cc1F)S(C)(=O)=O +CCOC(=O)N1CCCC(C(=O)OCc2ccccc2F)C1 +C#CCn1c(=O)nc2n1C(=O)N(c1ccc(Br)cc1)C2 +CCN(CC)S(=O)(=O)c1ccc(CCC(=O)N2CCCC2)cc1 +Cn1cc(CC(=O)NCc2cscn2)c2ccccc21 +Cn1cc(C#N)cc1C(=O)N1CC(=O)NC2CCCCC21 +CCC(C)n1nccc1NC(=O)c1cc(Cl)c2c(c1)OCCCO2 +Cc1cccc(N(CCC(N)=O)C(=O)c2coc(-c3ccccc3)n2)c1 +O=C(CC1CCCC1)N1CCCN(C(=O)Nc2ccccn2)CC1 +Nc1ccnc(C(=O)N2CCOC3CCCCC32)c1 +CCOc1ccc(F)c(C(=O)Nc2cn(C)c(=O)cc2C)c1F +Cc1ccc(OCCNC(=O)Nc2cn[nH]c2)cc1 +CCSc1ccc(C(C)NC(=O)N2CCCN(C(C)=O)CC2)cc1 +Cc1cccc(C(=O)NC(c2noc(C)n2)c2ccccc2F)n1 +COC(C)C(=O)NC1(CO)CC(C)CC(C)(C)C1 +CC(=O)Nc1cc(F)c(F)cc1NC(=O)Cc1cc(C)ccc1C +Cn1cc(CCNC(=O)c2ccnc(-n3cncn3)c2)cn1 +C=CCc1ccccc1OCC#CCNC(=O)c1cccn(C)c1=O +CCOc1ccc(-c2nc(-c3cccc(N)c3)n[nH]2)cc1OCC +COC(=O)C(NCC(F)(F)F)c1ccsc1 +CCc1ccc2oc(-c3ccccc3)c(OCC(N)=O)c(=O)c2c1 +COCCn1c(N2CCCCCC2)nc2c1c(=O)[nH]c(=O)n2C +CC(=O)N1CCN(c2ccccc2CNc2cc(F)cc(F)c2)CC1 +CCc1onc(C)c1NC(=O)CNC(=O)COc1ccccc1 +Cc1cc(C)n(Cc2cc(F)cc3cccnc23)n1 +O=S(=O)(NCc1ccccn1)c1cccs1 +C=CCn1c(C)cc(C(=O)CN(C)CCC#N)c1C +CN(C)C(=O)C1(CNC(=O)Nc2nnc(C3CC3)s2)CCCC1 +C#Cc1cccc(NC(=O)Cc2cccc(Cl)c2)c1 +COc1ccc(Br)c(C(=O)N2CC(C)CC(C)C2)c1 +CC(C(=O)c1ccc(N)cc1)N1CCN(c2ccc(F)cc2)CC1 +O=C(NCCn1ncc2c(N3CCCCC3)ncnc21)C1CC1 +Cc1ccc(CN(C)C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)cc1 +Cc1noc(CSc2nc(-c3ccccc3F)n[nH]2)n1 +CCNC(=O)C(C)Sc1nc2ccccc2n1CC +Cc1csc(C2CCCN(C(=O)COCc3nc(C)no3)C2)n1 +Cc1ccc(S(=O)(=O)N(C)CCCC(N)=O)cc1 +CC(=O)N1CCN(C(=O)c2c(F)cc(Br)cc2F)CC1 +COCCNC(=O)CSc1nnc(N)n1C(C)C +O=C(Nc1ccc2c(c1)OCO2)c1ccc(Cn2cncn2)cc1 +CN(CCOc1ccccc1F)C(=O)c1cn(C)nc1C(C)(C)C +O=S(=O)(NCC(O)(c1ccccc1)C1CC1)c1ccc(F)cc1 +CCN(CCC#N)C(=O)CN1c2cccc3cccc(c23)S1(=O)=O +CC(=O)c1cc(Br)ccc1NC(=O)C(C)n1cccn1 +O=C(COC(=O)c1ccc(F)cc1F)NCc1ccccc1 +O=c1oc(-c2ccncc2)nn1Cc1ccccc1F +Cc1ccc(C(=O)NC2COc3ccccc3C2=O)cc1 +COc1cccc(C(=O)C2CCN(C(=O)C(C)(C)C)CC2)c1 +O=C(NC1CCCCNC1=O)c1cc(Cl)ccn1 +CNC(=O)C1CCC(NS(=O)(=O)c2cccnc2)CC1 +CC(C)CC(=O)Nc1ccc(NC(=O)CN2CCCCCC2=O)cc1 +CCOc1ccc(NC(=O)Cn2nnc3ccccc3c2=O)cc1 +COC(=O)C(C)(C)NS(=O)(=O)c1ccc(OC)c(C)c1 +COCCN1CCC2(CCC1=O)CN(S(C)(=O)=O)CCN2C +O=S(=O)(c1cn[nH]c1)N1CCOCC(Cc2cnccn2)C1 +Cc1cc(C(C)NS(=O)(=O)CCCCC#N)c(C)o1 +CC(C)NC(=O)CN(C)C(=O)CC12CC3CC(CC(C3)C1)C2 +O=C(COc1ccc2c(c1)CCC2)Nc1cc[nH]n1 +Nc1nonc1-c1nc(-c2ccc(F)cc2Cl)no1 +O=C(C1CCOC1)N1CCCn2nnc(COc3cccnc3)c2C1 +CCn1ccc(-c2cc(=O)n3ncc(-c4ccccc4)c3[nH]2)n1 +CC(=O)c1ccc(OCC(=O)c2ccc3c(c2)OCCO3)cc1 +CC(NC(=O)NCc1cn(-c2ccccc2)nn1)C1CCCO1 +CC(C)C(=O)N1CCC(NC(=O)NC(c2ccccc2)C(C)C)CC1 +CCN(C(=O)Cn1nc(C)cc1C)c1ccc(C#N)c(Cl)c1 +O=C(OCC(=O)c1ccc(O)cc1O)c1ccc2c(c1)OCCCO2 +Cc1nc(C)c(C(=O)NCc2ccnc(OC(C)(C)C)c2)s1 +COc1ccccc1S(=O)Cc1nccn1Cc1ccccc1 +O=C(NCc1ccsc1)Nc1cccc(Cl)c1 +Cc1ccc2c(c1)OC(c1ccccc1)C(=O)N2CCC#N +COc1ccc(NC(=O)Cc2nnc(-c3cnccn3)o2)cc1 +CC(=O)Nc1ccc(O)c(C(=O)N(C)Cc2cccc3ccccc23)c1 +O=C(CSc1nncc2ccccc12)NCC1CCCO1 +Cc1ccc2cc(C(=O)NCCNC(=O)C3CC3)c(C)nc2c1 +CCSc1ccc(NCCN2CCOCC2)cc1 +CC(=O)N1CCCC1c1ccnc(-c2cccc(C(N)=O)c2)n1 +CCCOc1ccc(C(=O)Nc2nc(C)c(C)s2)cc1 +Cc1cccc(CNC(=O)CNc2ccc(C(=O)N(C)C)c(C)c2)c1 +COc1cccc(OCC(=O)NCC2CCCCO2)c1 +Cc1noc(COC(=O)c2cnn(-c3ccccc3)c2C)n1 +O=C(NCCC(O)c1ccco1)c1cccc(Cl)c1 +Cc1noc2ncn(CC(=O)NCc3ccccc3F)c(=O)c12 +CC(C)OCC(=O)NCCn1nc2ccccn2c1=O +Cc1cc(C(=O)N2CCCCC23CC(=O)N(C)C3)no1 +COc1cc(Nc2ncnc3c2cnn3C)cc(OC)c1OC +CC1CCCC(NC(=O)Nc2ccccc2-n2cccn2)C1 +Cc1ncccc1CN(C)CCC(=O)OC(C)(C)C +CC1(CNC(=O)NCCS(=O)(=O)c2ccccc2)CCCC1 +CC(=O)Nc1ccccc1CN1CCOC(c2ccccc2C)C1 +CCN(CC)C(=O)c1ccc(NCc2ccc(C#N)cc2)cc1Cl +CNC(=O)c1nc(-n2nc(C)cc2C)ccc1Cl +COC(=O)CCCS(=O)(=O)NC1(C#N)CCCC1 +Cc1ccc(-c2ncco2)cc1NC(=O)Cc1ccon1 +O=C(Nc1cnc2ccccc2c1)c1ccc(N2CCC(O)CC2)cc1 +CCCCn1c(SCc2csc(NC(C)=O)n2)n[nH]c1=O +CCC(CO)NC(=O)c1nnn(-c2ccc(C(F)(F)F)cc2)n1 +CCCNC(=O)C(C)NC(=O)c1cc(N)c(C)s1 +CCOC(=O)C(C)NC(=O)c1cccnc1SC +CC(=O)N1CCCN(C(=O)C(C)n2cncn2)CC1 +CCCNC(=O)c1cnc(COc2ccc(C)cc2)nc1N +Cc1cccnc1C(NC(=O)NC(C)C(=O)N1CCCCC1)C(C)C +COc1cc(C)sc1C(=O)NCC(C)(C)NS(C)(=O)=O +O=C(CSc1nc2sccc2c(=O)[nH]1)N1CCCCCC1 +COc1ccc(OC(=O)C2COc3ccccc3O2)cc1 +CN(Cc1cccc2ccccc12)C(=O)NCCN1CCOCC1 +Cc1c(C(C)NC(=O)c2cn(Cc3ccccc3F)nn2)cnn1C +Cc1nc(CNC(=O)CCNC(=O)c2cccs2)c(C)s1 +CCc1nc2cc(N)ccc2n1Cc1ccc(C)o1 +CCc1ncc2c(n1)CN(C(=O)c1ccc(C)n(CC)c1=O)C2 +CCS(=O)(=O)N(Cc1cccs1)Cc1cccs1 +Cc1cc(C)nc(C(C#N)C(=O)c2csc(-c3cnn(C)c3)n2)n1 +C#CCN1CCN(S(=O)(=O)c2ccc(C(F)(F)F)nc2)CC1 +CCOC(=O)C(CC)N1CCN(CC(=O)N2CCCCC2C)CC1 +CC1CCN(C(=O)c2cccc3c2OCCO3)C(C)C1 +Cc1ccc(-c2cc(CO)c(=O)n(C)n2)cc1Cl +Cn1nnnc1SCCC(=O)Nc1ccc(OC(F)F)c(F)c1 +COC(=O)C(C)n1cnc2sc(C(=O)OC(C)C)c(C)c2c1=O +Cc1nnc(SCc2nc(-c3cccc(Cl)c3)no2)s1 +CC(C)S(=O)(=O)c1ccccc1C(=O)NCCC1CC2CCC1C2 +NC(=O)C1CCN(C(=O)C2(c3cccc(Br)c3)CC2)C1 +NC(=O)c1ccccc1NC(=O)COCC1CCCO1 +Cc1sc2ncn(CC(O)CN3CCOCC3)c(=O)c2c1C +CC(C)c1n[nH]c(C2CN(Cc3cccc4c3OCCO4)CCO2)n1 +CC(C)C(c1cccnc1)N(C)C(=O)c1cccc(-n2ccnn2)c1 +FC(F)(F)C1CCCCC1NCc1ccncn1 +CN(Cc1cnn(C)c1)C(=O)Nc1cccc(NC(=O)C2CC2)c1 +O=S(=O)(Cc1noc2ccccc12)NCc1ccsc1 +COC(=O)CN(Cc1ccccc1Cl)S(=O)(=O)N(C)C +CCC(C)C(NC(=O)COC)c1nc2ccccc2[nH]1 +Cc1noc(-c2ccccc2)c1C(=O)NCCNC(=O)C(C)(C)C +O=C(CCCNc1ncccn1)N1CCN(c2ccccc2F)CC1 +CC(=O)N1CCN(C(=O)NCc2ccc(S(N)(=O)=O)cc2)CC1 +Cc1cc(C(=O)NCCCOC2CCCC2)c2c(=O)[nH]n(C)c2n1 +Cn1ccnc(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)c1=O +COC(=O)C1Cc2ccccc2N1C(=O)CCn1nc(C)cc1C +Cc1ccn2c(=O)c(-c3nc(-c4cccs4)no3)cnc2c1 +O=S(=O)(c1c[nH]cn1)N1CCOCC1C1CC1 +CNC(=O)C1CCC(NC(=O)NCCCCOC)CC1 +Cc1cc(C(=O)N2CC(C(=O)NCc3ccccc3F)C2)no1 +O=C1CN(C(=O)Cn2cnc3ccccc3c2=O)c2ccccc2N1 +CC1CC(C)CN(C(=O)c2n[nH]c3ccccc23)C1 +Cc1cc(C(=O)Nc2ccc(O)c(C(F)(F)F)c2)n(C)n1 +COc1ccc(COc2ccc(C(C)O)cc2)cc1 +Cc1nc(C(=O)N2CCN(c3cccc(F)c3C#N)CC2)cs1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)NCc1ccc(C#N)cc1 +O=C(Cn1ccnc1)NCc1cccc(NC(=O)Nc2ccccc2)c1 +CC(C)Cc1ccc(C(=O)CSc2ncnc3c2cnn3C)cc1 +O=C(C1CCCC1)N1CCN(Cc2cccc(Cl)c2)CC1 +O=C(NCCOc1ccccc1Cl)c1cccs1 +Cc1ccc(F)c2c1CCNC2C1=CC(O)C(O)C(O)C1 +CCn1cnc2c(cnn2-c2ccc(F)cc2)c1=O +COCCn1c(=NC(=O)c2cnccn2)sc2cc(F)ccc21 +OCCCN1CC(Cc2cccc(F)c2)Oc2ccc(O)cc21 +CCOC(=O)c1c(NC(=O)c2ccc(=O)n(C)n2)sc(C)c1CC +CCN(Cc1c(F)cccc1F)C(=O)NCc1ncn(C)n1 +CC1Oc2ccc(NC(=O)Cc3c[nH]c4ccccc34)cc2NC1=O +O=S1(=O)N=C(N(CCO)c2ccccc2Cl)c2ccccc21 +COc1cc(N)cn2cc(-c3cccc(NC(C)=O)c3)nc12 +CCc1ccc(NC(=O)N2CCC(O)(C(F)(F)F)CC2)cc1F +Cc1nc2c(c(=O)[nH]1)CCN(C(=O)c1ccccc1O)C2 +COc1cc(CNc2ccc3nnc(C(F)(F)F)n3n2)ccn1 +O=C(OCc1ccccc1)N1CCN(C2CCCCC2O)CC1 +CC(=O)c1ccc(Oc2ccc(C(=O)N(C)C)cc2)cc1 +CCn1nc(C)cc1C(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +Nc1c(Cl)cc(Cl)cc1C(=O)OCC(=O)N1CCNC(=O)C1 +CCCN(C(=O)c1ccc(OC)nn1)c1ccc(Cl)cc1 +O=C(NCc1cc2ccccc2[nH]1)c1cnc(C2CCCO2)s1 +COC(=O)c1cn(C2COC3C(NS(C)(=O)=O)COC32)nn1 +O=C(C1CC1)N1CCOCC1c1nccc(Nc2ccccn2)n1 +COc1ccnc(N2CCN(c3ccc(C#N)cn3)CC2)n1 +COC(=O)c1ccc(-c2nc(Cn3cccn3)co2)cc1 +Cc1ccccc1NC(=O)N1CCCn2cnc(COC(C)C)c2C1 +COc1cc2c(cc1C(=O)NCc1ccc(F)cc1)OCCCO2 +CCCCn1c(=O)nc2n1C(=O)N(c1cccc(OC)c1)C2 +C=CCn1c(SC(C)C(C)=O)nc2cc(Cl)ccc2c1=O +CCS(=O)(=O)N(C)Cc1nc2ccccc2[nH]1 +CS(=O)(=O)c1ccccc1NC(=O)C1CCOc2ccccc21 +Cn1cccc1C(=O)NC1CCN(C(=O)Nc2ccc(F)cc2)CC1 +COc1ccc(N)cc1-c1nnc(N2CCOCC2)o1 +Cc1noc(C)c1CN(C)Cc1nnnn1Cc1ccccc1 +O=C1OC(Nc2ccc(F)c(F)c2)c2ccccc21 +C#CCN(C(=O)c1cccnc1OCC)C1CCCCC1 +Cc1cccnc1NC(=O)CCCOc1ccc(F)cc1 +COC(=O)Cn1cc(CNC(=O)c2cn(C)nc2C(C)(C)C)nn1 +CCCc1ncc(C(=O)c2ccc(OC)cc2)n1C +c1cnc(N2CCCC3(C2)CN(C2CCOCC2)CCO3)nc1 +CCN(CC(C)C#N)S(=O)(=O)c1ccccc1 +O=C(NCCc1ccsc1)c1cncc(Br)c1 +COc1cc(C)ccc1OCC(=O)NCCc1ccccc1C +COCCc1nc(Cc2ccc(O)cc2)n(C2CCCCC2)n1 +C=CCn1c2c(ccc1=O)CC(NC(=O)c1cscn1)CC2 +CCC(=O)NCC(=O)NCc1cccc(C(=O)NC)c1 +C=CCc1cc(C(=O)NC(C)(C)C)cc(OC)c1OC +CC(C)CC1(CNC(=O)CN2CCCCC2=O)CCCC1 +COc1ccccc1NC1CCN(S(=O)(=O)c2cccnc2)CC1 +Cc1nc(C2COCCN2C(=O)COc2ccccc2C)cs1 +CC(C)Oc1cncc(Br)c1OC1CC1 +CCOc1ncccc1C(=O)N1CCC(CC(N)=O)CC1 +O=C(NCCCN1CCOCC1)c1cccc(N2CCNC2=O)c1 +Fc1ccc(Cn2cc(Cl)cn2)c(Br)c1 +COCCOc1cccc(CNC(=O)C2CCOC2)c1 +COc1ccc(OC)c(NC(=O)c2cc(OC)c(OC)c(OC)c2)c1 +Cc1cc(C)c(S(=O)(=O)N(Cc2nccn2C)C2CC2)c(C)c1 +Cc1ccc(NC(=O)NCCS(=O)(=O)N2CCCC2)cc1C#N +CCC(CC)NC(=O)Nc1cccc(NC(=O)C(C)OC)c1 +Cc1nc(N2CCCC2)cc(N2CCN(C(=O)C(C)(C)C)CC2)n1 +CCc1nc2n(n1)CCCC2NS(=O)(=O)c1cccc(F)c1 +CCC(C)NS(=O)(=O)c1ccc(C(=O)Nc2cccc(C)n2)cc1 +O=C(c1ccc[nH]1)N1CCC(Oc2ccccc2)CC1 +CC(C)(C)OC(=O)N1CCN(Cc2nc(C3CCCO3)n[nH]2)CC1 +Nc1cccc(-c2nnc(-c3ccncc3F)o2)c1 +Cc1ccc(CNC(=O)N2CCNC(=O)C2)c(OCC2CC2)c1 +CCNc1nnc(SC(C)C(=O)NC(C)(C)CC)s1 +CNC(=O)c1ccc(NC(=O)c2cc3cccc(OC)c3o2)cc1 +Oc1ccccc1N1CCN(Cc2nc(C3CC3)no2)CC1 +COC(=O)C(NC(=O)CCn1ncc2ccccc21)C(C)C +COc1cc(NCCNC(=O)Nc2ccc(C)c(F)c2)nc(OC)n1 +CCS(=O)(=O)c1nc2ccccn2c1S(N)(=O)=O +Cc1noc(C2CCN(c3oc(C)nc3C#N)CC2)n1 +CN(Cc1cc(Br)cs1)C(=O)CNC(N)=O +CC1CCCCC1NC(=O)Cc1ccc(-n2cccn2)cc1 +Cc1cc(F)ccc1CCNC(=O)N(C)Cc1nccn1C(F)F +CC(Oc1cccc(Br)c1)C(=O)N1CCN(C)CC1 +Cc1ccc(C(=O)CC2(O)C(=O)N(C)c3ccc(Cl)cc32)cc1 +Cc1nc(N2CCCC(N3CCNC3=O)C2)c2cnn(C)c2n1 +Cc1ccc(N(C)C(=O)C2CCCN2C(=O)C2CC2)c(C)c1 +CN(Cc1ccccc1F)C(=O)c1cccc(Cl)c1 +O=C(NCC(c1ccccc1)c1ccccc1)c1ccn2cncc2c1 +CCN(CC)C(=O)CN(C)S(=O)(=O)c1ccc(F)cc1Cl +Cn1cccc(NC(=O)C2(c3ccc(Cl)cc3)CC2)c1=O +CCC(O)c1ccc(OCC(=O)N2CCCC2)cc1 +CC(c1ccccc1)N(C)S(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1ccc(CNC(=O)c2cc(N3CCCC3=O)ccc2Cl)s1 +CCc1cc(N)cc2nc(-c3ccc(OC)c(OC)c3)oc12 +COc1ccc(NC(=O)C(C)Nc2cccc(CO)c2)cc1OC +O=C(Nc1ccc[nH]c1=O)c1ccc(N2CCOC2=O)cc1 +CCC(NC(=O)Nc1cccc(C(N)=O)c1)C(C)C +NC(=O)C1CN(c2ncc(Br)cn2)CCO1 +N#Cc1ccc(NC(=O)c2ccc(OCC(F)F)nc2)cc1Cl +CCOC(=O)c1ccsc1NC(=O)C1CCC1 +CC(C)c1ccc(N(CCCO)S(C)(=O)=O)cc1 +CCCc1ccc(NC(=O)c2ccc(F)c(S(N)(=O)=O)c2)cc1 +COc1cccc(C(=O)Nc2ccc3ccccc3n2)c1 +O=C(NCCCN1CCCC1=O)c1cnc(-c2ccccc2)s1 +COCCn1cnnc1C1CCCN(C(C)=O)C1 +COCCN1CCN(C(=O)NC(C)C(C)c2ccccc2)CC1=O +COCc1cc(C)nc2scc(NC(=O)c3ccccc3)c12 +COC(=O)N(C)CC(=O)NC(C)c1ccccc1 +C=CCCC(=O)N1CCCC1CS(=O)(=O)c1ccccc1 +CCOC(=O)CCC(C)NC(=O)c1cccc(Cl)c1F +Cc1nnc(S(=O)(=O)CCCC(C)(C)C#N)n1C1CCCCC1 +CC(=O)NC(C)(C)c1noc(CC2CCc3ccccc32)n1 +CC(=O)Nc1ccc(CC(=O)Nc2c(C)n[nH]c2C)cc1 +O=C(NCCN1CCN(C(=O)c2cccs2)CC1)c1cnccn1 +Cc1csc(CCCNC(=O)Cc2ccc(F)c(F)c2)n1 +CC1CCCN(C(=O)NCC(=O)N(C)CCc2ccccn2)C1 +CCCOc1ccccc1-c1ccc(C#N)c(=O)n1CC +COC(=O)CNc1ccccc1NC(=O)CC1C=CCC1 +CCn1cc(C(=O)OCc2cccc(F)c2)c(=O)c2ccc(C)nc21 +CN(CC(=O)N1CCNCC1)C(=O)c1ccsc1 +CC(O)(CNC(=O)C1CC=CC1)c1ccccc1Cl +Cc1cc(C(=O)Nc2c[nH]cc(Br)c2=O)sc1C +COCCOC1CC2CN(C(=O)Cc3ccc(OC)cc3)CCN2C1 +CN(CC(=O)NC(C)(C)C)c1cc(Br)ccn1 +Cc1cc2nccc(-c3ccc(Br)cc3)n2n1 +COC(=O)C1CCCCN1C(=O)c1cccn1C +C=C(C)CN(CC)C(=O)c1cnn(Cc2ccccc2)c1CC +CCC(NC(=O)C1CC(=O)Nc2ccccc21)c1ccc(Cl)cc1 +Cc1ccc(CSc2nc(N)cc(N)n2)cc1C +CC(C)N(C)C(=O)c1cccc(OCc2cscn2)c1 +CCN(CC)C(=O)c1ccc(Oc2ccc(C)nn2)cc1 +COCCNC(=O)C1CCCN(c2cnn(C)c(=O)c2)C1 +CCOC(=O)c1csc(C(=O)Nc2ccccc2)n1 +CCOC(=O)c1cccc2nc(CO)n(C3CCCC3)c12 +CCCC(=O)Nc1cccc(CNC(=O)c2ccc3[nH]cnc3c2)c1 +N#Cc1ccc(Cl)c(NC(=O)C2CC3CCC2O3)c1 +O=C(Nc1ccc2c(c1)OC1(CCCC1)O2)c1cccnc1 +CN(CCCNc1ccccc1N)c1ccccc1 +Cc1ccc(S(C)(=O)=O)cc1NC(=O)c1ccc(Cl)cc1F +C=CCN1C(=O)CNc2cc(Cl)c(Cl)cc21 +Nc1cc(NC(=O)CCn2ccccc2=O)ccc1Cl +Cc1cc(C(=O)N2CCN(Cc3cc(C#N)ccc3F)CC2)c(C)o1 +COc1ccc(C(=O)NCC(=O)NCC(C)C)cc1OC +O=C(Cc1nc(Cc2ccccc2)n[nH]1)Nc1ccc(F)cc1F +O=C(Nc1ccccc1)C1CCCN1C(=O)c1cnn2ncccc12 +Cc1ccc(Nc2ccccc2NS(=O)(=O)c2cn[nH]c2)cc1 +O=C(Cn1cnc2sccc2c1=O)c1ccccc1F +COCCOc1cc(C)ccc1NS(=O)(=O)c1ccccc1 +O=C(Nc1cccnc1N1CCCC1)c1ccc(N2CCCC2)nc1 +Cc1nc(N2CCN(C(=O)CC(C)C)CC2)cc(-n2cccn2)n1 +N#Cc1cccc(OCC(=O)N2CCCC2c2noc(C3CC3)n2)c1 +CCNS(=O)(=O)c1ccc(NC(=O)c2ccc3[nH]nnc3c2)cc1 +CCOC(=O)C1N=C(c2cccc(OC)c2)OC1=O +COC(=O)c1cccn1C1CCN(C(=O)CC(F)(F)F)CC1 +COCCNC(=O)NCC1CCN(C(=O)OC)CC1 +CCN(CCO)S(=O)(=O)c1ccc(F)c(Cl)c1 +CCc1noc(CC)c1CNCc1ccc(C#N)cc1 +Cc1cc(NC(=O)C23CCC(c4nc5ccccc5nc42)C3(C)C)no1 +Oc1c(F)ccc2c1CCNC2c1nccc2ccccc12 +Cc1ccccc1CNCC(O)c1cccc(F)c1 +C=CCC(O)(CC=C)CN1CC(=O)N2CCC(O)CC2C1=O +CC(C)C(CO)NC(=O)NCC1OCCc2sccc21 +CC1CCCC(NC(=O)NCc2ncn(C)n2)C1 +CC(=O)N1CCc2cc(C(=O)Nc3ccn(C)n3)ccc21 +COC(C)c1noc(CN(C)C(=O)NC2CCc3c(F)cccc32)n1 +O=C(c1cnn2c1OCCC2)N(Cc1ccccc1)c1ccccc1 +O=C(COc1ccccc1O)Nc1cccc(OC(F)(F)F)c1 +C#Cc1cccc(NC(=O)c2cc(OC)c(OC)c(OC)c2)c1 +O=C(Nc1ccc2c(c1)OCO2)NC1CCOc2ccccc21 +CC(C)CCC(=O)Nc1ccc(Cn2cncn2)cc1 +N#CC(C(=O)NCc1ccco1)c1nc2ccccc2[nH]1 +CCCCCNC(=O)Nc1ccc(S(=O)(=O)CC)cc1 +Cc1ccc(NC(=O)Cn2c(C3CCCO3)nc3ccccc32)cc1 +CN(C(=O)c1cccc(-n2cccn2)c1)c1cc(F)ccc1F +CCNC(=O)c1ccc(CNS(=O)(=O)N2CCCCCC2)cc1 +CNC(=O)c1ccc(NC(=O)CCC2CCCC2)cc1Cl +CC1CC(NC(=O)c2ccncc2)C(=O)N1c1ccccc1 +CCOc1c(O)ccc2c1C(c1cccc(C)n1)NCC2 +CCCNC(=O)c1cc(-c2cccc(Cl)c2)on1 +CS(=O)(=O)N1CCCC1C(=O)c1ccc2c(c1)OCCO2 +COc1ccccc1-n1cnnc1SCCNS(C)(=O)=O +COC(=O)CC(c1ccc(C(F)(F)F)cc1)c1c(O)n[nH]c1C +COCC1CCCN(C(=O)c2ccc(NC3CCC3)nc2)C1 +N#Cc1ccc(C(F)(F)F)nc1NC1CCCCC1CO +Cc1sc2nc(CN3c4ccccc4CC3C)[nH]c(=O)c2c1C +COc1cccc(OC)c1OCC(=O)NC1CCCCC1 +Cc1nc(C)c(C(=O)OCC(=O)N2CCOCC2)s1 +CC1(C)CCC(CNC(=O)COCC2CC2)CC1 +CCn1nccc1C(=O)N(Cc1ccccc1)Cc1ccccc1 +CS(=O)(=O)N1CCN(CCC(=O)Nc2ccccc2)CC1 +CCCCC(CC)CNC(=O)c1ccc(=O)n(C)c1 +CCOC(=O)c1nn(-c2ccccc2Br)cc1C(C)=O +COCCOc1cccc(NC(=O)N2CC(C)CCC2C)c1 +Cn1cnc2cc(C(=O)N3CCCC4(CC3)CNC(=O)O4)cnc21 +COCC(C)NC(=O)Nc1ccc(Cl)c(F)c1 +CCn1nnnc1COc1cccc(C(=O)NCC(=O)N(C)C)c1 +Cc1ccc(CNC(=O)CNC(=O)CC(C)(C)C)cc1 +CC(=O)N1CCN(C(=O)Cc2nc3cc(N)ccc3o2)CC1 +CN(CC(O)COCc1ccccc1)C(=O)c1ccc(Cl)cc1O +Cc1nc2ccccc2nc1COC(=O)C1COc2ccccc2O1 +Cc1ccnc(NC(=O)c2onc(-c3ccccc3)c2N)c1 +Cn1c2c(ccc1=O)CCN(C(=O)N1CCOCC1)CC2 +CCN(C(=O)CSc1cccc(C(F)(F)F)c1)C1CC1 +Cc1cccc(C(=O)Nc2ccc(CN3CCOCC3)cc2)c1C +Cc1cc(C(=O)N2CC(C)OC(c3ccccc3)C2)c(C)n1C1CC1 +NC(=O)c1cc2c([nH]c1=O)CCCC2NC(=O)c1ccccc1Cl +Cn1ncc(NC2CCOC2c2ccccc2)c(Cl)c1=O +COCCN1CC(C(=O)Nc2nc3c(C)cc(C)cc3s2)CC1=O +N#Cc1c(-c2ccoc2)cc(-c2cnn(-c3ccccc3)c2)nc1N +CCCS(=O)(=O)N1CCC(NC(=O)NC(C)CC)CC1 +C=CCNC(=O)Nc1cccc(NC(=O)C(C)OC)c1 +COc1ccc(CN2CCN(c3ncccn3)CC2)cc1C +CC(c1ccccc1Cl)N(C)C(=O)c1cnn(C(C)(C)C)c1 +O=C(c1c[nH]nc1-c1ccccc1Cl)N1CCOCC1 +Cc1cccc(OC(C)C(=O)NCc2ccncc2)c1C +CCOc1nc2ccccc2nc1C(=O)Nc1cccc(C(C)=O)c1 +COCC(=O)Nc1ncc(Cc2ccc(Cl)cc2C)s1 +O=C1CCCc2c1cnc1nc(C(F)(F)F)nn21 +CCNC(=O)c1cccc(NS(C)(=O)=O)c1C +COC(=O)c1cc(-c2ccc(OC(C)C)cc2)n[nH]1 +COCc1nnc2sc(Cc3ccc(Cl)cc3)nn12 +O=c1cc(COc2ccc(F)cc2F)nc2ccccn12 +CC1(CNC(=O)NCc2cccnc2OCC(F)(F)F)CCCC1 +CC(=O)c1ccc(Sc2cnn(C)c2)c(Br)c1 +CCN(C(=O)c1ccc2c(c1)nc(C)n2C)c1ccc(OC)nc1 +Cc1ccc(-c2cnn3c(=O)cc(CCc4c(C)noc4C)[nH]c23)cc1 +COCc1cc(C)nc2sc(C(=O)N(C)c3ccccc3)c(N)c12 +Cn1ccnc1COc1ccc(COC(=O)c2cncc(F)c2)cc1 +COc1ccc(CNC(=O)N2CCN(c3ncccn3)CC2)cc1 +CCN1C(=O)CSc2cnn(CC(=O)Nc3ccccc3)c(=O)c21 +O=C(CN1CCCC1=O)NCc1ccc(C(F)(F)F)cc1 +COc1ccc(-c2nc(COc3ccc(C)nc3)no2)cc1 +Cc1nc(Cn2cnc3sc4c(c3c2=O)CCCCC4)oc1C +O=C1CCCN1C1C2CC3CC1CC(C2)C3N1CCCC1=O +Cc1cc(C)nc(SCC(=O)N(C)CC(O)C2CC2)n1 +Cc1cccc(OCCCC(=O)Nn2cnc3ccccc3c2=O)c1 +COC(=O)C1CCCN1C(=O)Cc1ccc(OC)cc1 +CN(Cc1cnc(N(C)C)nc1)Cc1nc2ccccc2[nH]1 +N#Cc1ccccc1CN1C(=O)C(=O)c2ccc(Br)cc21 +COC1COC2(CCCN(C(=O)c3ccncn3)C2)C1 +CCC1CCCN(C(=O)c2ccc(OCc3cscn3)cc2)C1 +CCC1=C(C(=O)OC)C(c2ccc(C(=O)OC)cc2)NC(=O)N1C +N#Cc1c(NC(=O)COc2ccccc2)sc2c1CCCC2 +CS(=O)(=O)N1CCC(C(=O)Nc2ccc3scnc3c2)CC1 +CCOc1ccc(OCC(=O)N(C)CC(=O)N(C)C)cc1 +CN(CCCNc1ccc2nnnn2n1)c1ccccc1 +Cc1ccccc1OCc1nnc2n1CCCCC2 +O=C(C1CCC1)N1CCc2onc(-c3ccc(Cl)cc3)c2C1 +Cc1cccn(Cc2coc(-c3cccc(Cl)c3)n2)c1=O +CSc1ccc(Cl)c(C(=O)N(CCC#N)CCC#N)c1 +CCNC(=O)CN(C)C(=O)c1ccc(NC(N)=O)cc1 +CN(C)S(=O)(=O)N1Cc2cncn2CC(COCC2CC2)C1 +CCc1cc(C(=O)NCC2CN3CCCCC3CO2)[nH]n1 +COC(=O)c1sccc1NC(=O)N1CCN(C(C)=O)CC1 +CC(C)CC(NC(=O)c1cccc(C#N)c1)C(=O)N(C)C +Cc1ccccc1C(C#N)NC(=O)Cc1cccnc1 +CN(CCC#N)S(=O)(=O)c1cc(N)ccc1F +CC(=O)c1oc2ccccc2c1NC(=O)C(C)Sc1nncs1 +CC(=O)c1cccc(Nc2ncnc(N3CCC(C)CC3)c2N)c1 +Cc1ccc(CN(C)C(=O)c2csc(-c3ccc(C)o3)n2)o1 +COC(=O)Nc1cccc(C(=O)NCCc2nc(C(C)C)no2)c1 +CCN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c1ccccc1 +COc1ccc(CCC(=O)N2CCc3ncncc3C2)cc1 +Cc1ccc(NC(=O)N(C)Cc2ccoc2C)c(F)c1 +O=C(CCNCC(F)(F)F)N1CCCC(n2cncn2)C1 +COc1ccc2c(ccn2CC(=O)OCc2cccc(C(N)=O)c2)c1 +Cc1cc(C)c(CNC(=O)c2cc3ccccc3s2)c(=O)[nH]1 +N#CCOc1cccc(CC(=O)Nc2ccc(C(N)=O)cc2F)c1 +CC(=O)OCC#CC(Cc1ccccc1)OC(C)=O +COC(=O)C1=C(C)NC(=O)NC1c1cc(C)ccc1C +CCOC(=O)c1ccc(NS(C)(=O)=O)c(C)c1 +CC(C)Oc1ccc(CNC(=O)c2cc(-c3ccncc3)cn2C)cc1 +COc1ccc(NC(=O)CCC(=O)c2ccccc2)cn1 +Cc1nc2c(c(C)c1CC(=O)N1CCCC(C)C1)c(=O)[nH]n2C +CC(=O)Nc1cccc(NC(=O)NCC2Cc3ccccc3O2)c1C +CCC1NC(=O)C2CN(CC3CC3)CCN2C1=O +CC(C1CC1)N(C(=O)CN1CCN(C(=O)N(C)C)CC1)C1CC1 +NC(=O)c1cccc(CC2CCN(C(=O)c3cn4cccnc4n3)C2)c1 +COc1cc(C)c(Cl)cc1C1NCCN(C)C1=O +CC(=O)c1csc(NC(=O)c2ccnc(OC3CCC3)c2)n1 +CC(C(=O)NCCC1=CCCCC1)N1CCN(c2nccs2)CC1 +Cc1noc(C2CN(S(=O)(=O)c3ccc(C(F)(F)F)cc3)C2)n1 +CCOC(=O)C1=C(CN2CCCC(C)C2)NC(=O)NC1C +Cc1nn(-c2ccccc2)c(C)c1C(=O)n1ncnc1N +CCCn1c(N)c(NCc2nc(C)no2)c(=O)[nH]c1=O +CC(NC(=O)C1COCC(=O)N1Cc1ccccc1)c1cccs1 +O=C(NCCc1ccccn1)N1CCCC1c1ccc(F)cc1 +CC(C)CCOC(C)C(=O)Nc1nnc(C(C)(C)C)s1 +CC(C)n1nccc1NC(=O)c1cnn(-c2ccccc2)n1 +CCn1nc(C)c(NCc2cnn(Cc3ccccc3)c2)c1C +O=C(NCc1ccccc1)N1CCCC(c2nnc3ccccn23)C1 +CCn1cc(C(=O)N2CCN(CC(=O)NC3CC3)CC2)c(C(C)C)n1 +Cc1c(-c2nc(-c3cc4ccccc4o3)no2)cnn1-c1ccncc1 +Cc1ccc(Cl)cc1-n1cc(C)c(C)c(C#N)c1=O +Cn1c(=O)c2c(ncn2CCSc2ccc(F)cc2)n(C)c1=O +NC(=O)c1ccc(OCC(=O)N2CCCCCC2)cc1 +Cc1noc(C)c1C(C)NS(=O)(=O)N1CCCC(C)C1 +Cn1nc2n(c1=O)CCN(CC(O)c1cccc(F)c1)C2 +CN(C)c1cccc(C2CCCN2S(=O)(=O)c2cn(C)cn2)c1 +COC(=O)c1ccc(NC(=O)CCn2ncc3ccc(C)cc32)cc1 +COCCNC(=O)Cn1cnc2sc(C(N)=O)c(C)c2c1=O +Cc1ccccc1C1CN(Cc2cccc3c2OCO3)CCO1 +Cc1cccc2[nH]c(C3CCCN(C(=O)CCc4ccncc4)C3)nc12 +O=C(CCCc1nc2ccccc2c(=O)[nH]1)Nc1ccc(F)cc1F +Cc1occc1COC(=O)c1cc(F)cc(F)c1 +C=CCNC(=O)C(Cc1cccc(OC)c1)NC(C)=O +Cc1[nH]c(-c2ccccc2)nc1C(=O)N1CC2C3CCC(O3)C2C1 +COC1CCCC1OC(=O)C1CC(=O)N(Cc2ccco2)C1 +CC(C)n1nccc1NC(=O)NCC1CCN(c2ccccc2)C1 +O=C(COC(=O)C12CC3CC(CC(O)(C3)C1)C2)N1CCOCC1 +CNC(=O)c1cccc(CNc2cc(NC(=O)C(C)C)ccc2C)c1 +C=CCNC(=O)c1ccc(OCC=C)c(Br)c1 +Cc1cccc(-c2nc(N)n(C(=O)Cc3ccccc3)n2)c1 +CN(C(=O)c1cnc(-c2ccco2)s1)c1ccc(C(N)=O)cc1 +COCC1CN(C(=O)NC(C)Cc2ccc(C)cc2C)CCO1 +COc1cc(C)ccc1NC(=O)c1[nH]nc(C)c1Br +Cc1noc(C)c1C(=O)NC(C)C(=O)N1CCCC1 +CCCn1nccc1NC(=O)CNC(=O)c1cccc(Cl)c1 +Cc1cc(NC(=O)c2cn3cccnc3n2)ccc1Oc1cccnc1 +CNC(=O)c1ccc(-c2ccccc2OC)nc1N +CC(C)Sc1ccccc1C(=O)NC(C)c1ccco1 +O=C(CCc1nc2sc3c(c2c(=O)[nH]1)CCCC3)NC1CC1 +COC(=O)c1c(NC(=O)c2ccco2)sc2c1CCCCC2 +Cc1cc(C)nc(SCC(=O)OCC(=O)NC2(C#N)CCCC2)n1 +CC(=O)c1ccc(Oc2c(C#N)c(=O)n(C)c(=O)n2C)cc1 +COc1cc(CNc2cnn(-c3ncccn3)c2)c2c(c1)CC(C)O2 +COc1cccc(Cn2cnc3cc(N)ccc32)c1 +Cc1cc(C(=O)Nc2ccc(S(=O)(=O)C(F)F)cc2)no1 +O=C(Nc1cn[nH]c1)C1(c2ccc(F)cc2F)CCCC1 +COC(=O)c1n[nH]cc1-c1cc(-c2cn(C)nc2C)nc(N)c1C#N +CCc1ccc(NC(=O)c2cc3c(=O)n4ccccc4nc3n2C)cc1 +CCOC(=O)c1cc2n(n1)C(C(F)(F)F)CC(c1ccccc1)N2 +Fc1ccc(F)c(N2CCN(Cc3cccc4cn[nH]c34)CC2)c1 +Cc1ccnc(NC(=O)C2CCN(S(N)(=O)=O)CC2)c1 +Cc1c(C(=O)OCC(=O)N(C)C)oc2ccc(Br)cc12 +CCCCn1nc(C(=O)NC(C)(C)C)ccc1=O +O=C(NCc1ccco1)C1CCN(c2ccc3c(c2)OCCO3)C1=O +Cc1nc(CSc2nc3ccccc3c(=O)n2C2CC2)cs1 +COc1ccc(-c2ccc(NC(C)=O)cc2)c(OC)c1OC +CC(NC(N)=O)C(=O)NCCNC(=O)c1ccc(Cl)cc1 +CCNc1cc(S(=O)(=O)N2CCCC(O)C2)ccn1 +COCC1CCC2C(CCN2C(=O)Cc2ccc(F)cc2)O1 +Cc1c(-c2cccc(CO)c2)c(C(F)(F)F)nn1C +O=C(Nc1cc(F)cc(F)c1)c1cccnc1OCC(F)(F)F +Cc1ccc2ncc(C(=O)Nc3ccc4c(c3)OCO4)n2c1 +Cc1ccc2c(cnn2CCC(=O)NCCCn2nc(C)cc2C)c1 +O=S(=O)(N1CCCC1)n1c(Cc2ccccc2)nc2ccccc21 +Nc1nc2c(c(=O)[nH]1)C(c1cccc3ccccc13)CC(=O)N2 +Cc1cc(C(=O)NCC2(c3cccs3)CC2)no1 +Cc1ccc(C(=O)NC(C(=O)OC(C)C(N)=O)C(C)C)cc1 +COc1ccc(-c2nnc(COC(=O)c3cccc(O)c3)o2)cc1 +CCN(CC)C(=O)C1CCCN(C(=O)OC(C)(C)C)C1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2ccccc2C(F)(F)F)c1 +CC(=O)Nc1cc(C(=O)Nc2cc(C)n[nH]2)ccc1F +O=c1c2nnsc2ncn1Cc1ccc(Cl)cc1 +CC(C)(C#N)OC(=O)C1CCN(C(=O)c2ccccc2)CC1 +Cc1nn(C)c2nc(NCc3nc(-c4ccccn4)no3)sc12 +Cc1cc(N)nc(SCc2ccc3ccccc3n2)n1 +CCCCCNC(=O)C(N)c1ccc(C(C)C)cc1 +Cn1cc(C(=O)CSc2ncnc3ccccc23)cn1 +Cc1ccc(NC(=O)CN(C)C(=O)Cc2ccccc2Cl)nc1 +Cc1ccc(NC(=O)NCC(F)(F)F)c(OCC(=O)N(C)C)c1 +Cc1cc(C)cc(CCNC(=O)c2ccc(-n3cncn3)cc2)c1 +O=C(Nc1nc2c(s1)CN(C(=O)c1ccno1)CC2)c1ccoc1 +O=C1CC(c2noc(-c3ccccc3)n2)CN1Cc1ccccc1 +COc1cc2c(cc1OC)CN(C(=O)CSc1ccccn1)CC2 +CCN1CC2(CCN(C(=O)CCc3ccc(=O)[nH]n3)CC2)CC1=O +CCS(=O)(=O)N1CCC(C(=O)N2CCC3(CC2)OCCO3)CC1 +COc1ccc(S(=O)(=O)N2CCOCC2C2CC2)cc1C +CC(Oc1ccccc1Cl)C(=O)N1CCN(Cc2ccco2)CC1 +O=C(NCc1cccs1)Nc1nc2ccccc2s1 +CC(=O)NCC(=O)NCc1ccc(Br)cc1 +Cc1cc(NC(=O)NC(C)c2ccc(O)cc2)n(CCC(C)C)n1 +COC(C)(C)c1noc(-c2cnn(-c3ccccc3)c2)n1 +O=C(Nc1ccc2c(c1)OCCO2)Nc1cc(F)ccc1F +O=C(OCn1nnc2ccccc2c1=O)c1ccccc1C(F)(F)F +CCOc1cc(NC(=O)c2cnc3ccccn3c2=O)ccc1OC +COc1ccccc1C1CC1C(=O)Nc1cccnc1-n1cccn1 +COc1cc(NCc2cnc(N3CCOCC3)nc2)cc(OC)c1 +CN(C)S(=O)(=O)CC(=O)Nc1ccccc1F +O=C(Nc1cc(-n2cccc2)ccc1F)N1CCCC1 +COCCn1cc(NC(=O)N2CCCC(O)C2)cn1 +C=CCCC(=O)N1CCCc2cc(Cl)cc(F)c21 +CC(=O)Nc1cc(C(=O)N(C)C2CCCCCC2)ccc1C +O=C1CCC2(C(F)(F)F)Nc3cc(F)ccc3N12 +COc1ccccc1OCCNC(=O)c1cc2c([nH]c1=O)CCCC2 +COc1cc(CNC(=O)c2cnc(C3CCCO3)s2)ccn1 +CCCNC(=O)c1cccc(NC(=O)c2ccco2)c1 +COC(=O)c1sc(NC(=O)CCC2CCCOC2)nc1C1CC1 +CC1CCN(C(=O)C(C)S(=O)(=O)c2ccccc2Cl)CC1 +CC1CCC(OC2CCN(C(=O)Nc3cccnc3)CC2)CC1 +CC1CC(Sc2ccccc2Br)C(=O)O1 +Cc1ccc(CC2(c3ccc(Br)cc3)NC(N)=NC2=O)o1 +CCNc1ncc(C(=O)N2CCN(CC(=O)NC(C)C)CC2)cn1 +Cc1cc(C(=O)Nc2cccc(C(=O)N3CCOCC3)c2C)[nH]n1 +COc1cc(N)c(NC(=O)COc2c(C)cccc2C)cc1OC +CCCC(=O)Nc1ccc(C(=O)Nc2cc(C)ccn2)cc1 +CCc1cnc(NCc2cc(-c3ccccc3)n[nH]2)nc1 +O=C(Nc1nc2cc3c(cc2s1)OCCCO3)c1ccncc1 +CC(C)(C)NS(=O)(=O)c1ccccc1CNC(=O)C1CC=CC1 +COc1ccc(NC(=O)CSc2ccccc2Cl)cc1OC +Cc1csc(COc2cccc(-c3nnco3)c2)n1 +Cc1nnc(SCc2nnc(-c3ccccc3)o2)o1 +CCOC(=O)N1CCC(NC(=O)NCCc2cc(C)cc(C)c2)CC1 +CCOC(=O)N1CCC(n2c(=O)[nH]c3ccccc3c2=O)CC1 +Cc1cnc(N2CCOCC3(CCC(Cn4cccn4)O3)C2)nc1 +CCOC(=O)Cc1ccc(OC)c(Br)c1 +CCCn1c(CNS(=O)(=O)c2ccc(C)cc2)nc2ccccc21 +COc1ccc(NC(C)=O)c(NC(=O)Cc2ccc(C)c(OC)c2)c1 +COC(=O)N1CCCN(c2nc(C(F)F)nc3ccccc23)CC1 +CCCCCNC(=O)NC1CCOc2c(Cl)cccc21 +CN(CCC#N)C(=O)c1cccc(OCc2ccccc2C#N)c1 +CCOC(=O)c1cc(-c2ccccc2OC)[nH]c1N +COc1ccc(C(=O)c2nccn2C)cc1C(C)(C)C +Cc1cc(N2CCN(C(C)C#N)CC2)ccc1Br +N#Cc1ccc(NC(=O)CCCNC(=O)c2ccccc2)cc1Cl +C=CCN(CC=C)C(=O)COc1ccc2ccc(=O)oc2c1 +CCCn1nccc1NC(=O)CCC(=O)c1cc(C)sc1C +COc1cccc(NC(=O)Cn2cnc(C)cc2=O)c1 +Cc1cc(C(=O)CCC(=O)Nc2ccccc2C)c(C)s1 +Cc1cccc(-n2ccnc(NCCCOC(C)C)c2=O)c1 +O=C(Nc1ccc(F)cc1F)c1ccc(S(=O)(=O)C(F)F)cc1 +CCN(CC)C(=O)CCC(=O)NCc1ccc2c(c1)CCC2 +COc1ccccc1NC(=O)CSc1nccnc1-n1cccn1 +CCC(C)C(=O)CSc1nnnn1Cc1ccco1 +O=C(CCNC(=O)c1ccc(Cl)cc1)Nc1ccc(F)c(F)c1 +CCN(C(=O)COc1ccc(C(F)(F)F)cc1)C1CCC1 +O=C1COc2cc(NC(=O)c3cnccn3)c(Cl)cc2N1 +CCCNC(=O)c1cccc(OCc2nnnn2C(C)C)c1 +CC(=O)NC(C)C(=O)NC(c1ccccc1)C1CC1 +O=C(NCc1cccc(Cl)c1)C1(n2cnnn2)CCCCC1 +O=C(NCCSc1ccc(Cl)cc1)c1ccoc1 +NC(=O)C(NCc1ccc(Cl)cc1)c1ccccc1 +Cc1ccsc1CNC(=O)NC1CCCCC1CO +C#CCN1CCN(C(=O)NCCNC(=O)C(C)C)CC1 +COc1ccc2c(c1)OCC(C(=O)NCC#Cc1ccccc1)C2 +CC1CCCC(C)N1C(=O)Cn1cnc(C2CCC2)cc1=O +Cc1nc(CCN(C)C(=O)c2csc(Cc3ccccc3)n2)no1 +CC1CN(C(C)c2ccc(OC(F)F)cc2)CC(C)O1 +O=C(c1ccco1)N1CCN(C(=O)c2n[nH]c3c2CCCC3)CC1 +CC1(C(=O)NCCc2cccc(F)c2)Oc2ccccc2NC1=O +CCC1OCC2CN(C(=O)c3cn4cc(Cl)ccc4n3)CCC21 +CC(=O)c1ccc2c(c1)N(C(C)C(=O)OC(C)C)C(=O)C(C)(C)O2 +Cc1nnc(SCC(=O)Nc2ccccc2SC(F)F)s1 +OCc1nnn(-c2ccc(O)cc2)c1-c1ccc(Cl)cc1 +COC(=O)NC(C)(C)C(=O)NCC1(CC(C)C)CCCC1 +CC(=O)Nc1c(C)cc(NC(=O)NCCc2cscn2)cc1C +CC(NC(=O)c1cccc(-c2nnnn2C)c1)c1ccccc1 +Nc1nc2c(cc1C(=O)Nc1ccc(F)cc1)CCCC2 +COCCC(=O)N1CCCc2c(C#N)nn(C)c2C1 +Nc1cccc(NC(=O)c2cc(Cl)ccc2O)c1 +c1ccc(-c2nc(-c3ccncc3)cc(-c3ccccn3)n2)cc1 +CN(C)C(=O)Nc1cc(C(=O)N(C)C)ccc1Cl +c1cc(CCCNc2ccc(-c3nc(C4CC4)no3)cn2)ccn1 +Cc1cc(NC(=O)CCc2nc(-c3ccncc3)no2)ccn1 +O=C(NCc1ccccc1)N1CCC(OCc2ccccc2)CC1 +COCc1nc(C(=O)NC2CCN(C)C2=O)cs1 +C#Cc1cccc(NC(=O)c2cccc(OCC(N)=O)c2)c1 +Cc1cc(C)cc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1 +CC(=O)NCC(=O)NCC(=O)Nc1ccc(Br)c(C)c1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)c1ccc(Cl)cc1O +CCn1nc(C)cc1C(=O)NCc1ccc(C)cc1 +Cc1csc(C(C)NC(=O)NCC2CC=CCC2)n1 +COC(=O)C(NC(=O)CCc1ccco1)c1cc(F)ccc1F +CCCC(=O)NC(C(=O)NC)c1ccc(F)c(F)c1 +O=C(Cc1ccc2c(c1)CCCC2)NCc1nnc2ccccn12 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1cc(F)cc(F)c1 +CCNC(=O)C(C)NC(=O)Nc1ccc(Cl)c(Cl)c1 +Cc1cc(C)n2nc(C(=O)NCCc3ccccc3F)nc2n1 +O=C1COc2cc(NC(=O)NCCc3ccc(Cl)cc3)ccc2N1 +C#CCN1CCN(CC(=O)NC2CCCC(C)C2C)CC1 +O=C(COc1ccc2ccc(=O)oc2c1)Nc1cccnc1 +Cc1ccc(S(=O)(=O)Nc2ccc(CS(N)(=O)=O)cc2)s1 +CC(=O)Nc1ccc(-c2noc(C(C)(C)C)n2)cc1 +CC(NS(C)(=O)=O)c1cccc(Br)c1 +CCOc1ccc(NC(=O)c2cccc(OCC(N)=O)c2)cc1Cl +CCC(C)CN(C)S(=O)(=O)c1cccc(Cl)c1C#N +CN(C)C(=O)CC1C(=O)NCCN1Cc1cccc(F)c1F +Cc1cscc1C(=O)N1CCC2C(CCC(=O)N2C2CC2)C1 +O=C(Nc1nonc1-c1ccccc1)c1ccccc1F +Cc1ccc(CN(C)Cc2cccc(C#N)c2)s1 +COC(=O)Nc1ccc(CNC(=O)c2cc3ccccc3s2)cc1 +Cc1cnoc1C(=O)OCc1noc(C(C)(C)C)n1 +N#Cc1cc2c(n(-c3ccccc3F)c1=O)CCNC2 +Cc1cccc(C(C)NC(=O)c2ccncc2F)c1C +CCOC(=O)C1=C(C)C(C(=O)NC2CCCC2)C(C)=N1 +COc1ccc(NC(=O)C2CCN(C(=O)c3ccco3)CC2)cn1 +O=C(NCC(c1ccccc1)c1ccccc1)c1ccc[nH]c1=O +COCC(NC(=O)c1nnn(-c2ccc(C)cc2)c1C1CC1)C(N)=O +Cc1nc(NCCCn2ccnc2)cc(-c2ccncc2)n1 +CCCNC(=O)Cn1c(=O)c(=O)n(C)c2ccccc21 +C=CCNc1nnc(SCc2nc3ccccc3c(=O)[nH]2)s1 +COc1cccc(N2CC3(CCN(C(=O)C4CCCO4)C3)CC2=O)c1 +NC(=O)CCC(=O)N1CCN(c2ccccc2)CC1 +COc1cccc2cc(C(=O)Nc3cccc(-n4nnnc4C)c3)oc12 +Cc1ccc(NC(=O)Cn2nnc3ccccc32)cc1F +COC(=O)CCc1c(C)nc(-c2ccncc2)[nH]c1=O +Cc1cc(CN(C)Cc2nc(N)c3c4c(sc3n2)CCCC4)no1 +CC(C)CC(O)c1cc(F)c2c(c1)C(C)(C)C(=O)N2 +CCc1ccc(C(=O)NCC2COc3ccccc3O2)o1 +CCN(Cc1cnc2ccccn12)C(=O)c1cccc(OC)c1 +CC(O)CCN(C)c1ccc(Br)cn1 +O=C(NCC1CCCO1)c1cc(-c2ccc(OC(F)F)cc2)[nH]n1 +Cc1ncsc1COC(=O)c1ccc(CCNC(N)=O)cc1 +Cn1cncc1C(=O)c1ccccc1C(=O)c1ccccc1 +COc1cc2nc(C)n(CC(F)(F)F)c2cc1OC +O=C(CNc1ccccc1-n1cccn1)N1CCOCC1 +CC(C)OCCC(=O)NCC(=O)Nc1ccc(Br)cc1 +CCSc1nc(N)c(NC(=O)c2ccc(C)cc2)c(=O)[nH]1 +COc1ccccc1CC(=O)Nc1ccc(-c2nc[nH]n2)cc1 +Cc1cccc(C)c1OCCN1CCN(C(=O)C2CCCO2)CC1 +CC(C)C(C)(C#N)NC(=O)CSc1nc2ccccc2n1C +O=C(NCCc1ccccn1)NCC1CCCCO1 +CS(=O)(=O)NCCNC(=O)C1CC(=O)N(c2ccccc2)C1 +O=C(NCc1ccsc1-n1cccc1)c1cnn[nH]1 +Cc1nnc2n1CCN(C(=O)c1cc(C3CC3)n(C(C)(C)C)n1)C2 +CCOc1ccc(OC(C)C(=O)Nc2ccc(C(C)=O)cc2)cc1 +Fc1cccc(CC2CN(Cc3cccs3)CCO2)c1 +O=C(Nc1cccc(S(=O)(=O)N2CCCC2)c1)C1CCCCC1 +CC(=O)c1nc2ccc(F)cc2n1C(C)(C)CO +CS(=O)(=O)c1nccn1-c1ccc(F)c(F)c1 +CS(=O)(=O)c1ccc(NC(=O)NCC2(c3ccccc3)CC2)cn1 +COCCN1C(=O)CCC12CCN(C(=O)N(C)C)CC2 +O=C(CCC1CCCO1)Nc1cc(Cl)ccc1Cl +Cn1cc(C(=O)NCC2(c3cccs3)CCOCC2)nn1 +O=C(Nc1ccc(O)cc1)Nc1ccc(-n2cccn2)cc1 +Cc1cnc(C(C)NC(=O)N2CCOCC2C2CC2)s1 +COC(=O)C1=C(C)C(C(=O)NCCc2ccc(Cl)cc2)=NC1C +CSc1ccc(C2NC(=O)c3oc4ccc(C)cc4c(=O)c32)cc1 +O=C(Nc1ccc2c(c1)COC2)c1cnc(-c2ccccn2)s1 +Cc1cc(Cl)cc(C)c1CNc1ccc2[nH]nc(C(N)=O)c2c1 +COc1cc(CNC(=O)CCc2ccc(C)cc2)ccn1 +CC(C)c1nccc(CN2CCCC(c3ccn[nH]3)C2)n1 +Cc1cc(C)n2ncc(C(=O)NCCCOCc3ccco3)c2n1 +CCCC1CCC(NC(=O)NCCN2CCOCC2)CC1 +CCC(C)N(CCOC)c1nc2sccn2c1CO +COC(=O)Nc1cc(NC(=O)Cc2ccccc2C)ccc1F +O=S(=O)(NCc1ccc2c(c1)OCO2)c1ccccc1O +CN(C)C(=O)N1CCC(C(=O)N(C)c2cccc3ncccc23)CC1 +O=C1CCN(C(=O)NCc2cn(-c3ccccc3)nn2)CCN1 +NC(=O)CCN(Cc1ccccc1)C(=O)c1cc(=O)[nH]c2ccccc12 +COc1cc(C)ccc1OC(=O)Cn1c(=O)cnc2ccccc21 +Cc1ccc(NC(=O)c2cccc(-n3cnnn3)c2)c(C)c1 +CS(=O)(=O)N(CCc1ccccc1)CC(=O)Nc1ccccc1 +COc1cccc2ccc(-c3nccn3Cc3c(C)noc3C)nc12 +CCNC(=O)N1CCN(C(=O)c2cc(C)n(C(C)C)c2C)CC1 +Cc1nc(COc2cccc(C(=O)N(C)c3ncccc3F)c2)no1 +CCN(CCn1nc2ccccn2c1=O)c1ccccc1 +CCc1ccccc1Nc1nc(N)nc(CN(C)C)n1 +OCc1nnn(CCOc2cccc3ccccc23)c1C1CC1 +CC(C)C(=O)Nc1cccc(NC(=O)c2cccnc2)c1 +COc1c(Cl)cccc1NC(=O)NCC1CCCOC1 +Nc1n[nH]c2c1C1(CCCCC1)Cc1ccccc1-2 +Cc1cc(C(=O)N2CCCCC2C(=O)NCc2ccc(F)cc2)no1 +CN(C)C(=O)N1CCN(C(=O)c2ccc(O)c(Cl)c2)CC1 +Cc1cc(C)c(C#N)c(NC2CCN(C(=O)CC(C)C)CC2)n1 +CN(Cc1ccc2nonc2c1)C(=O)c1cccc2nccnc12 +Cc1cc(C(N)=O)ccc1NC(=O)c1cncc(Br)c1 +C=CCn1nnc(NC(=O)c2ccc(-c3ccccc3Cl)o2)n1 +CCS(=O)(=O)NC1CCSc2ccccc21 +COC(=O)c1ccccc1OCCn1cnc2ccccc2c1=O +COc1ccc(COCCCC(=O)N2CCc3[nH]ncc3C2)cc1 +Cc1cc(CNC(=O)c2cc3c(C)nn(C)c3s2)ccc1F +CC(=O)c1c(C)[nH]c(C(=O)OCc2cccc3cccnc23)c1C +CCOC(=O)C1(NCC(F)(F)F)CCCCC1C +COc1ccc(C(=O)Nc2ccc(Cl)c(Cl)c2)nn1 +Cc1nnc(NC(=O)c2cccc3c2OC(C)C3C)s1 +Cc1nnc(SCc2ncc(-c3ccccc3)o2)n1C1CC1 +CCOCC(=O)N1CC2CCCC2(COCc2ccccn2)C1 +CN(C(=O)c1cnns1)C1Cc2ccccc2C1 +CCOC(=O)c1cnn(C(C)C)c1C(F)(F)F +Cc1noc(CN2CCN(c3ncnc4cccc(F)c34)CC2)n1 +COc1ccccc1CN(C(=O)CCn1cncn1)C1CC1 +O=C(c1ccccc1F)N1CCCC(OCCOc2ccccc2)C1 +CN(Cc1nc(-c2cccs2)no1)C(=O)COc1ccccc1 +C#Cc1cccc(NCC(=O)NCc2cccc(C(=O)NC3CC3)c2)c1 +O=C(CC1C=CCC1)Oc1cccc(C(=O)NC2CC2)c1 +NC(=O)N1CCCC(C(=O)N2CCNC(=O)C2)C1 +Cc1ccc(C(C)N(C)C(=O)C2CC(=O)N(C(C)C)C2)cc1 +O=C(COC(=O)Cc1n[nH]c(=O)c2ccccc12)NCC(F)(F)F +COc1ccc(Cc2nc(-c3cccc(N)c3)cs2)cc1 +COc1cc(OC)c(C(=O)NCCc2ccccc2F)cc1OC +CC(=O)Nc1ccc(C)c(NCc2ccccc2C#N)c1 +Cc1cc2c(cc1Br)CCNC2c1nc[nH]n1 +CCC1CCCC(NC(=O)C(C)NS(=O)(=O)c2cnn(C)c2)C1 +CCCN(C)S(=O)(=O)c1cc(-c2nnc(C)o2)co1 +CC(C)C(c1ccccc1)N(C)Cc1ccc(S(C)=O)cc1 +COc1ccccc1CCNC(=O)c1n[nH]c2c1CCCCC2 +Cc1cc(Cl)cc(NC(=O)c2ccco2)c1O +CCOC(=O)c1c(C)nc(N)nc1Cc1ccccc1C +O=C(NCCNC(=O)c1ccn2ccsc12)c1cccc(Cl)c1 +CCOC(=O)c1c(C)oc(N)c1C(=O)c1ccc(F)cc1 +CCCOc1ccc(C(=O)c2cccc(C)n2)cc1 +O=C(Nc1ccc(F)cc1)c1ccc2[nH]c(C(F)(F)F)nc2c1 +Cc1nc2ncnn2c(C)c1CCC(=O)Nc1ccc2[nH]ncc2c1 +CCN(c1ccc(C(=O)NC2CCN(C(=O)OC)CC2)cc1)C(C)C +COc1cc(C(C)NC(=O)CNC(C)=O)ccc1OC(C)C +COC(=O)c1cccc(C(=O)C(C#N)c2nc3ccccc3o2)c1 +CC(=O)N1CCC(c2ncncc2-c2cc(C)no2)CC1 +Cc1noc(CCCC(=O)N2CCC(N3CCNC3=O)CC2)n1 +COCc1ccc(C2CCCN2C(=O)NCc2ccc(C)s2)o1 +Cc1cc(C(=O)NCc2cn(-c3ccccc3)nn2)c2cnn(C)c2n1 +Cc1ccc(C(=O)N2CCCC(C(=O)Nc3cc[nH]n3)C2)cc1 +CCc1ccc(C(C)NC(=O)COc2ccccc2C(N)=O)cc1 +Nc1nonc1-c1nc(-c2ccc(Br)cc2)no1 +CC(C)(C)OC(=O)N1CCC2NC(=O)CCC2C1 +COc1ccc(NC(=O)C2CCCN(S(=O)(=O)N(C)C)C2)cc1 +O=C1CN(c2ncnc3c2Cc2ccccc2OC3)CCN1 +COc1ccc(-c2c(C)sc3nc(CO)cn23)cc1OC +Cc1ccc(C)c(OCC(=O)NC(C)c2nnc3n2CCCCC3)c1 +CCC(Oc1ccccc1)C(=O)Nc1ccccc1C(=O)NC +Cc1cccc(C(C)C)c1NC(=O)C(C)Nc1cccc(CO)c1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)NCCOc1ccccc1 +COc1cccc2c1OCC(Cc1ccc(C)nn1)C2 +Cn1c2ccc(F)cc2c2nnc(SCC(=O)N3CCCC3)nc21 +Cn1cc(N2CCN(c3ncnc4ccc(F)cc34)CC2=O)cn1 +CC(C)C(=O)NC1CCN(C(=O)c2sccc2C2CC2)CC1 +Cc1c(C(=O)NCC(C)O)sc2nc3n(c(=O)c12)CCCCC3 +C=CCc1ccc(OCC(=O)N(C)C(C)C)c(OC)c1 +COC1CCCC(OC(=O)c2ccn(-c3ccccc3F)n2)C1 +COc1cc2[nH]c(C(=O)Nc3ccc(F)cc3)cc2c(OC)c1OC +O=c1cc(-c2ccc(O)cc2)oc2ccc(O)cc12 +CC(C)(C)c1ccc(S(=O)(=O)NC2CCCCNC2=O)cc1 +CCOC(=O)c1cc(C#N)ccc1Br +CCNC(=O)CNC(=O)NC(C)c1ccc(F)c(Cl)c1 +CC(=O)Nc1ccc(C(=O)Nc2nc3c(s2)COCC3)cc1 +COc1cccc(CC2NCCc3ccc(O)c(F)c32)c1 +Cc1ccccc1OCC(=O)Nc1ccc2c(c1)OCCCO2 +Cc1n[nH]cc1-c1nc(-c2cccnc2Oc2ccccc2)no1 +CNC(=O)c1ccc(CN(Cc2cc(C)on2)Cc2ccco2)cc1 +O=C(NC1CC1)C1CCN(c2ccc(-c3ccccc3)nn2)CC1 +Cc1cc(C)c(NC(=O)C2CC3CCCC(C2)C3=O)c(C)c1 +CCC(CC)N(C)C(=O)C1CC(=O)N(C2CC2)C1 +CCCCCNC(=O)NCc1cccc(NC(C)=O)c1 +CSc1ccccc1NC(=O)Cc1ccccc1F +CCCc1noc(CNc2cc(Cl)ccc2C(N)=O)n1 +Cc1cccc(CNc2ccccc2C(N)=O)c1C +CC(=O)Nc1ccc(C)cc1NCC(=O)N1CCCC(C(N)=O)C1 +O=c1[nH]c(=O)n(Cc2ccccc2)c2c1CN(Cc1cccnc1)CN2 +Cc1cc(NC(=O)N2CCCC2CO)nn1-c1ccccc1Cl +CC(=O)N1CCN(C(=O)CCC(=O)c2ccccc2)CC1 +O=C(NCCCc1ccccn1)c1cc2ccc(F)cc2[nH]1 +CCOc1ccc(C(=O)N2CCC(O)CC2)cc1F +CCOc1ccc(Nc2ncnc3c2nnn3C)cc1 +Cc1nc(COc2ccc(CNc3ccc4c(c3)COC4)cc2)no1 +O=C(COC1CCCC1)NCc1cc(-c2ccccc2)no1 +CCOc1ccccc1OC(C)C(=O)NCc1ccc(F)cc1 +CC(C)CCCNC(=O)Nc1ccccc1CC(N)=O +Cc1ccc(Br)c(C(=O)CC#N)c1F +CN(C)C(=O)N1CCC2OCCC2(COCc2cccnc2)C1 +CCCNC(=O)c1cccc(CNC(=O)Nc2nccs2)c1 +O=C(OCC=Cc1ccccc1)c1ccc(-n2cncn2)nc1 +COc1cccc2c1ccn2CC(=O)Nc1ncccc1C +CNC(=O)C1CN(C)CCN1C(=O)c1n[nH]c2c1CCCC2 +COc1ccc(C(=O)N2CC3(C)C4CCC3(C)C2(C#N)C4)cc1 +COCCn1c(SCC(=O)Nc2cccc(C)c2)nc(C)c1C +COC(=O)C(NC1CCN(C(=O)C2CCCC2)C1)c1ccccc1C +COc1ccc(C(=O)NCCN2CCOCC2)cn1 +Cc1nn(C)c(C)c1NC(=O)C(C)Oc1ccc(F)cc1Cl +N#Cc1nnc2ccccc2c1NCc1ccc2c(c1)OCO2 +O=C(c1n[nH]c2ccccc12)N1CCN(C(=O)N2CCOCC2)CC1 +COc1ccccc1COC(=O)c1cccc(O)c1 +CCn1nc(C(C)C)cc1C(=O)N(C)Cc1cc(C)on1 +Cc1ccnc(NC(=O)Cn2nc(C(F)(F)F)cc2C)c1 +NC(C(=O)Nc1nc2ccccc2s1)c1ccccc1 +Cc1ccccc1C(O)CNC(=O)c1cc(C(N)=O)cn1C +CCCS(=O)(=O)N1CCCCC1C(=O)NCC(O)c1ccco1 +Cn1cc(NC(=O)COc2ccc(Cl)c(Cl)c2)ccc1=O +CC(C)NC(=O)c1c2c(nc3ccccc13)CCC2 +Cc1cc(C)c(C#N)c(SCC(=O)N2CCC(C(N)=O)CC2)n1 +CCc1noc(CC)c1CC(=O)Nc1ccc(CC#N)cc1 +CCCc1c(C(=O)N2CCC(c3ccccc3)CC2)cnn1C +C=CCC1(CC=C)CCN1C(=O)c1cc(-c2ccccn2)n[nH]1 +CCCN(CC(=O)OCC)c1ncc(C#N)cc1Cl +Cc1ccc(N2CC(C(=O)NCc3cccc(Cl)c3)CC2=O)cc1 +CCOc1ccccc1C1CCN(C(=O)c2sc(C)nc2C)CC1 +CCc1ccc(CCC(=O)OCC2CCCO2)cc1 +Cc1nc(C(=O)OCC2CC(=O)N(CCc3ccccc3)C2)cs1 +CC(C)NS(=O)(=O)c1ccc(C(=O)N2CCCCC2C)cc1 +O=C(C1CCCc2[nH]ncc21)N1CCOCC1C1CC1 +CCC(C)n1ncc(C(=O)N2CC(O)C2)c1C1CC1 +COCC(O)CN(C)C(=O)CSc1ccccc1Cl +O=S(=O)(NCCc1c[nH]c2ncccc12)c1cccs1 +CC(O)CNC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +O=C(NCCCn1cnc2ccccc21)c1ccc(-n2cccn2)cc1 +Cc1csc(C2CCN(S(=O)(=O)c3cccs3)CC2)n1 +COc1ccc(CNC(=O)NCCc2cccs2)cc1C +O=C(c1ccccc1)N1CCN(C(=O)c2cccs2)CC1 +COc1cc(OC)cc(C(=O)Nc2cc(F)ccc2F)c1 +COCC(O)CN(C)C(=O)C1CC(=O)N(C(C)C)C1 +Cc1noc(NC(=O)C2CC(=O)N(c3cc(F)cc(F)c3)C2)n1 +O=C(Nc1ccncc1)N1CCN(Cc2c(F)cccc2Cl)CC1 +c1ccc(Cn2nc(C3CCOC3)nc2-c2ccoc2)cc1 +Cc1nn(C)c2ncc(C(=O)Nc3cccc(C(=O)NC4CC4)c3)cc12 +CCOc1cccc2cc(C(C)NC(=O)N3CCOCC3)oc12 +Cn1nc(C2CCC2)cc1NC(=O)c1cccnc1OCC(F)F +CCCNC(=O)NC(C)c1cnn(-c2ccccc2C)c1C +Cc1ccccc1-n1nnnc1SCC(=O)N1CCCCC1 +COC(=O)c1cn(Cc2ccc(C(F)(F)F)cc2)cc(F)c1=O +Cc1cc2c(cc1S(=O)(=O)NCc1ccco1)n(C)c(=O)n2C +CC(C)(C)NS(=O)(=O)c1cc(Cl)ccc1Cl +O=C(Nc1nnc(CS(=O)(=O)c2ccccc2)o1)c1ccco1 +O=C(NC1CCCC1)c1csc(-n2cccc2)n1 +Cn1c(C(=O)NCc2n[nH]c(=O)[nH]2)cc2cc(C(F)(F)F)ccc21 +CCNC(=O)c1ccc(CNC(=O)c2ccncc2)cc1 +COc1ccc(C(=O)C(O)c2ccc(OC)cc2)cc1 +O=C(Nc1cccc(-c2nc3ccccc3o2)c1)c1ccncc1 +COc1ccc(C(=O)Nc2nnc(-c3cc(C)oc3C)o2)cc1OC +CC(C)(C)C1NC(=O)CN1C(=O)OCc1ccccc1 +CNC(=O)c1cc(N2CCCC2)nc2ccccc12 +Cc1ccc(S(=O)(=O)N2CCN(Cc3ccccn3)CC2)cc1 +Cc1cc(NC(=O)CSc2nc(C)cc(C)n2)ccn1 +Cc1cc(NC(=O)CNc2ccccc2OC(F)(F)F)n(C)n1 +OCc1c(-c2ccc(F)cc2)nc2sc(-c3cccnc3)nn12 +O=C(NCc1ccncc1)c1csc(NCc2ccccc2)n1 +O=C(Cn1c(=O)n(C2CCCC2)c2ncccc21)NCc1ccco1 +Cc1cccc(Oc2ccccc2CNS(=O)(=O)CC#N)c1 +CCN(CC)C(=O)CCC(=O)Nc1ccnn1-c1ccccc1C +COCCNC(=O)c1cc(C2CCCN(Cc3ccccn3)C2)no1 +Nc1nc2n(n1)CCC(c1ccc(OCc3ccccc3)cc1)C2 +CC(C)CC(CO)NC(=O)Nc1ccc(F)cc1 +Cn1cnnc1CCC(=O)N1CCNC(c2ccccc2)C1 +COc1ccc(Cl)cc1C1NCCN(C)C1=O +Cc1cccc(CC(=O)Nc2ccc(-n3ccnc3C)nc2)c1 +COCCN(CC(=O)N(C)C)Cc1cnc2cc(C)ccn12 +Cc1ccccc1C(=O)NC(CC(C)C)C(=O)N1CCC(C(N)=O)C1 +CC(=O)c1ccc(S(=O)(=O)NCc2ccccc2)cc1 +CNS(=O)(=O)Cc1ccc(CNC(=O)c2ccc[nH]c2=O)cc1 +CCCS(=O)(=O)NCC(C)(C)c1ccncc1 +Cn1cc(CCC(=O)Nc2[nH]ncc2-c2cccc(Cl)c2)cn1 +COC(=O)C1=C(C)C(C(=O)OCC(=O)N2CCCCCC2)=NC1C +COc1cccc(-c2noc(NCc3ccc(C)cc3)n2)c1OC +COCc1ccccc1CNC(=O)c1cccc(C(F)(F)F)c1 +COc1ccc(Cl)cc1N(C)C(=O)c1ccc(SC)nc1 +CC(NC(=O)c1ccc(=O)[nH]c1)c1cc2ccccc2o1 +CCS(=O)(=O)N1CCCCC1CNS(C)(=O)=O +O=C(Nc1ccc(CN2CCOCC2)cc1)Nc1ccc(F)cc1F +COc1ccc(S(=O)(=O)Nc2ccc(C(N)=O)cc2)cc1F +COC(=O)CC(C(=O)c1ccc(F)c(C)c1)N1CCOCC1 +N#Cc1ccc(NC(=O)CCCOCC2CCCO2)cc1 +CC(C)CC1COCCN1Cc1noc(C(C)C)n1 +O=C(COC(=O)c1ccc[nH]c1=O)NCCc1ccc(F)cc1 +Cc1ccc(OC(C)C(=O)NCCS(N)(=O)=O)cc1 +Cc1noc(C)c1CNC(=O)C1CCN(c2cnccn2)CC1 +CC(C)Oc1cc(OC2CC2)cnc1C(F)(F)F +COCC(C)(CCO)NC(=O)Nc1ccc(C)c(Br)c1 +CC(NC(=O)c1cccc(-n2cccn2)n1)C(=O)Nc1ccccc1 +Cn1cnc(CNC(=O)c2ccccc2SCC2CCCO2)n1 +O=C(NC1CCc2c(F)cccc21)c1n[nH]c(=O)[nH]1 +CS(=O)(=O)c1cccc(C(=O)Nc2ccc(-n3cncn3)nc2)c1 +Cc1ccc(NC(=O)c2ccccc2)c(NC(=O)c2ccc[nH]2)c1 +COc1cc(OC)cc(-c2nccn2Cc2cccc(O)c2)c1 +CCc1ccc(CNC(=O)NCCNC(=O)c2ccc(F)cc2)s1 +CCc1cc(=O)oc2cc(OC(C)C(=O)NC3CC3)ccc12 +Cc1ncc(CN(C)Cc2nc3ccccc3c(=O)n2CC#N)s1 +Cc1csc(=O)n1CCN1CCCC1c1nnc2ccccn12 +O=C(Cn1ccc(=O)[nH]c1=O)NCc1nc2ccccc2s1 +CCOC(=O)c1cc(-c2cc(OC(C)C)ccc2OC)nn1C +O=C1CN(C(=O)CN2CCOc3ccc(F)cc32)c2ccccc2N1 +CCOCCCNS(=O)(=O)c1ccc(C#N)cc1 +CC(=O)Nc1ccc(Br)cc1NC(=O)CCC(C)(C)C +CN(CCOCC1CC1)C(=O)Cn1c(=O)[nH]c2ccccc2c1=O +CCc1ccc(CCNC(=O)c2n[nH]c(=O)[nH]2)cc1 +COc1ccc(C(C)=O)cc1Cn1nc(C)c(C)c(C#N)c1=O +Cn1c2ccccc2n2c3ncccc3c(=O)c(C#N)c12 +COc1nc(N)nc(N)c1S(=O)(=O)c1ccccc1 +Cc1ccc(NC(=O)C2CC2)cc1NC(=O)NC(C)CO +CCc1nn(C)c(OC)c1CN1CCOC(c2nc(C)cs2)C1 +CC(=O)c1ccccc1NC(=O)CCCNC(=O)c1ccc(F)cc1 +O=C(CN1CCN(CC2OCCO2)CC1)N1CCc2ccccc21 +CNC(=O)CN(C)C(=O)Cc1ccc(-n2cccn2)cc1 +Cc1cc(C)nc(NC(=O)NCCCn2nc(C)cc2C)c1 +C=CCn1cc(C(=O)NCCCC(N)=O)c2ccccc21 +O=C(Cc1ccc(-c2cccnc2)cc1)N1CCc2nocc2C1 +Cc1ccc(O)c(NC(=O)C2(c3ccccc3F)CC2)c1 +CC(c1ccco1)N(C)C(=O)c1cc(COc2cccc(F)c2)[nH]n1 +CCCNC(=O)CSc1nc2ccccc2n1CC +CC(=O)NCCNC(=O)CSc1nc(C2CC2)nc2ccccc12 +Cc1ccc(S(=O)(=O)Nc2ccc(C(=O)NC(C)CO)cc2)cc1 +CCCc1n[nH]c(C2CN(C(=O)c3ccc(C#N)c(C)n3)CCO2)n1 +CN(C(=O)COc1ccccc1C#N)C1CCCCC1 +CCCNC(=O)NC1CCN(c2ccc(F)cc2)C1=O +CNC(=O)c1cc(C)nc(C2(C)CCCN2C(=O)Cn2ccnc2)n1 +O=C(Nc1ccc2c(c1)nc1n2CCOC1)C1CCCCC1 +CCCOc1ccccc1-n1nnc(C(=O)OCC)c1N +COc1ccc(-c2nc(NC(=O)c3cc(C)oc3C)sc2C)cc1 +CNC(=O)C1CCCCC1NC(=O)Cc1c(Cl)cccc1OC +CCC1(CCC(=O)NCc2nc3ccccc3s2)CCC(=O)N1 +COc1ccc(-c2cc(CO)c(C3CC3)o2)c(OC)c1OC +CC(C)Nc1ncccc1C(=O)N1CC(C)OC(c2ccccc2)C1 +O=C(Nc1cccnc1)C1CCCN1C(=O)C1CC1 +CCC(NC(=O)NC(C)c1ccc(C)o1)c1ccc2c(c1)OCCO2 +O=C(Cc1ccc(F)c(F)c1)N1CCC2(CC1)OCCO2 +COc1cc(CNC(=O)NCc2ncc(C)c(OC)c2C)ccn1 +CCC(C(=O)NC1CCCCC1)N1CCN(C(=O)C(C)(C)C)CC1 +O=C(NC1CCCN(Cc2ccccc2)C1=O)N1CCCC(CO)C1 +COc1cccc(CNC(=O)CCn2ccccc2=O)c1 +CN(C)C(=O)c1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)cc1 +O=C1CCC(COC(=O)c2csc(-c3cccc(Cl)c3)n2)N1 +Cc1ccc(OCCC(=O)N2CCC(c3nncn3C)CC2)c(C)c1 +O=C(NCC1CCN(C(=O)c2ccoc2)CC1)c1ccccn1 +CC(C)c1csc(NC(=O)C2CC(=O)N(C(C)C)C2)n1 +CC(C)C(Oc1ccc(F)cc1F)C(=O)OCC(N)=O +O=C(CCNC(=O)c1ccncc1)NC(c1ccccc1)C1CCC1 +Cc1nc(NC(=O)c2cccs2)nc2c1C(=O)CC(C)C2 +COc1ccc(OCCOC(=O)c2ccc(O)cc2)cc1 +CC(O)CN1CCN(CC(=O)N(C)Cc2cccc(F)c2)CC1C +Cc1ocnc1CNC(=O)Nc1ccc2c(c1)OCO2 +CC(Oc1cccc(F)c1)C(=O)N(C)Cc1ccccc1 +O=C(Nc1ccccc1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +O=C(Nc1cccn(Cc2ccc(F)cc2)c1=O)C1C2CCCC21 +CC(C)n1ccnc1-c1cc(NCc2cccnc2)nc2[nH]ccc12 +O=C(CCn1ccc(=O)[nH]c1=O)Nc1ccc(-n2ccnc2)nc1 +CC(NC(=O)Cc1ccc(F)cc1F)C(=O)N1CCCCC1C +O=C(NC1CCCN(c2cccc(F)c2)C1)c1ccsc1 +Cc1nonc1C1CCCN1C(=O)c1cn2ccsc2n1 +Cc1ccc(CC(NC(=O)Nc2cc(C)on2)c2cccnc2)cc1 +Cc1ccc(C2CC2c2nc(CC(=O)NC3CCCC3)no2)s1 +COC(C)C(=O)NCc1ccc(-n2nc(C)cc2C)nc1 +CNC(=O)Cc1csc(NC(=O)C2CN(C(C)=O)C2)n1 +NC(=O)c1cccc(S(=O)(=O)N2CCCc3ccccc32)c1 +CN(CCC#N)C(=O)c1cccc(Cl)c1Cl +CCc1oc(-c2ccc(OC)c(OC)c2)cc1C#N +Fc1cc2c(c(F)c1F)CCNC2C1CCCO1 +Fc1cncc(C2NCCc3ccc(F)c(F)c32)c1 +CCN(Cc1ccncc1)S(=O)(=O)c1ccc(Cl)cc1 +COCCn1cc(NC(=O)Nc2cccc(F)c2)c2ccccc21 +Cc1csc(N(C(=O)C(C)C)c2ccccc2)n1 +O=c1ncccn1Cc1cccc(Nc2ncnc3ccccc23)c1 +O=C(Cn1nnc2ccccc21)Nc1ccc(Cl)c(Cl)c1 +Cc1nc(-c2cccnc2)[nH]c(=O)c1CC(=O)NCCc1ccco1 +O=C(CCCc1ccc(Cl)cc1)Nc1cnn(CC2CCCO2)c1 +Cc1ccc(CN(C)S(=O)(=O)c2cc(F)ccc2F)s1 +CC(=O)Nc1nnc(SCc2cc(=O)n3ccsc3n2)s1 +CCCSc1ncccc1C(=O)N1CCCC1 +O=C(Nc1ccccc1Oc1ccccc1)c1cnns1 +COCCN(C(=O)Cc1c(C)noc1C)c1nc2ccccc2s1 +Cc1cnc(N2CC3(CCN(c4nccs4)C3)C2)nc1 +COCc1noc(-c2ccc(N3CCOCC3)nc2)n1 +COc1cc(OC)c2[nH]c(C(=O)NCCNC(C)=O)cc2c1 +N#Cc1cccc(C(=O)N2CCC(c3nnc(-c4ccco4)o3)CC2)c1 +Cc1cccc(OCCNC(=O)NC2CCN(C(=O)C3CC3)CC2)c1 +O=C1CC2(CCN(C(=O)c3cc4ccccc4[nH]3)C2)Oc2ccccc21 +CCOc1ccccc1C1CC(=O)NC2=NC(C)=NC(=O)C21 +Cc1ccc(SCCC(=O)Nc2cccc(N)c2)cc1 +c1csc(-c2n[nH]c(SCc3nnc(C4CC4)n3C3CC3)n2)c1 +O=C(c1ccncc1)N1CC2CCC(C1)N(C(=O)c1ccco1)C2 +O=C(CCCNC(=O)c1ccco1)Oc1cccc(Cl)c1 +COc1ccccc1C(NC(=O)c1ccc(C#N)cn1)C(C)(C)C +CCCC(NC(=O)c1cccnc1OCC)c1ccccc1 +Cc1cc(C)c(C)c(OC(=O)C2CC3CCC2O3)c1 +O=C(C(c1ccccc1)N1Cc2ccccc2C1=O)N1CCCC1 +O=C(c1cnccn1)N1CCN(Cc2ccc(Cl)cc2)CC1 +Cc1ccc(SCCNC(=O)OCC(F)(F)F)nc1 +NC(Cc1ccc(Cl)c(Cl)c1)C(F)(F)F +O=S(CC(O)(c1ccccc1)c1ccccc1)c1ccccc1 +CCOCCn1c(SCC)nc2c1c(=O)[nH]c(=O)n2C +CCc1cc(OC)c(C(=O)CN2CCC(=O)CC2)cc1OC +O=C(NCC(F)(F)F)N1CCCN(CC(F)(F)F)CC1 +Cc1ccc(NC(=O)NCCN2CCOCC2)c(C)c1 +Cc1nc(NCC(C)C)sc1C(=O)Nc1cccc2[nH]ccc12 +Cn1nnc2cc(C(=O)N3CCC(Cc4ccccc4)CC3)ccc21 +O=C(NCC(c1cccc(F)c1)N1CCOCC1)C1CC=CC1 +CC1CC1C(=O)OCc1nnc(-c2ccc(Cl)cc2)o1 +C#CCNS(=O)(=O)c1ccc(C(=O)OCc2cccnc2)cc1 +Fc1cc(CN2CCc3sccc3C2)c2ncccc2c1 +CC1c2ncc(COc3cccnc3)n2CCN1C1CCC1 +CN(C)C(=O)CN1CCN(C(=O)c2ccccc2)CC1 +CCOc1ccc2nc(NC(=O)CN3CCCCCC3=O)sc2c1 +CSc1sc(NC(=O)C(C)c2ccsc2)nc1C +CCC1(O)CCN(c2nc(C(N)=O)cs2)CC1O +COC(=O)C(C)(C)NC(=O)Cc1ccc(F)c(F)c1 +O=C(NCCNc1ncccn1)N1CC=C(c2ccccc2)CC1 +Fc1cnc(-c2ccc(-c3ccn[nH]3)cc2)nc1N1CCOCC1 +CCOc1cc2c(cc1OCC)CN(S(=O)(=O)N(C)C)CC2 +COC(=O)C(C)n1ccnc1-c1cccc(Cl)c1 +CCC(NC(=O)c1cnc2n(c1=O)CCS2)c1ccc(Cl)cc1 +CC(Sc1nc2cc(Cl)ccc2[nH]1)c1nc(C2CC2)no1 +CCc1nc(NC(=O)c2nn(-c3ccccc3)nc2C)sc1C +c1ccc(-c2ncn(CC3CCCO3)c2-c2ncc[nH]2)cc1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)Oc1cccc(F)c1 +CN1CCN(C(=O)C2CCN(c3ccccc3F)CC2)CC1 +O=C(Cc1cccc(F)c1)NCCC(=O)N1CCc2nocc2C1 +O=C(Nc1ccc(Cl)cn1)c1cnn2c(-c3ccco3)ccnc12 +Cc1cc(CN(C)C(=O)c2ccc3c(c2)C(=O)c2ccccc2-3)no1 +CC(C#N)N(C)C(=O)c1ccc(C(F)(F)F)cc1 +Cc1nc(C(NC(=O)Cc2ccccc2)c2ccccc2)n[nH]1 +COc1cccc(COC(C)C(=O)Nc2cc(F)c(F)c(F)c2)c1 +CCN1C(=O)CSc2cnn(CC(=O)NCc3ccco3)c(=O)c21 +CC(C)(C)c1nnc(CNc2cccc(C(=O)N3CCCC3)c2)o1 +CC1CCc2nn(CC(=O)Nc3ccc4c(c3)OCCO4)cc2C1 +CC(C)C(=O)Nc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1 +CC(=O)c1cc(-c2ccc(C)cc2C)nn(C)c1=O +O=C1CC(c2ccccc2)N(C(=O)c2cc(C3CC3)[nH]n2)CCN1 +COc1cc2cc(C(=O)Nc3nc(C)cs3)[nH]c2cc1OC +O=C(Nc1ccc(F)cc1)NC1CCN(C(=O)COCC2CC2)CC1 +Cc1ccc(SCCC(=O)NCC2CC2)cc1C +O=C(NC1CCCCC1)c1cccc(-n2nnc3cccnc32)c1 +CC(C)(C)CC1CCCN1C(=O)NCCCN1CCOCC1 +COC(=O)C(C)N1CCN(Cc2cc(C)on2)CC1 +CC(C)C(C)OC(=O)c1cnc(C2CCCO2)s1 +COc1cc(C)sc1C(=O)NC(C)C(=O)Nc1ccccc1 +Cc1cccc(C)c1NCc1c(F)cc(F)cc1F +O=C(c1ccc2c(c1)OCCCO2)N1CCOCC1 +CC1CN(C(=O)c2cc3c(s2)CCC3)C(C)CO1 +CC(O)c1nc2ccccc2n1CC(=O)N1c2ccccc2CC1C +CC(NC(=O)Nc1ccc2c(c1)COC2)C1CCCO1 +N#CCCCSc1ncnc2c1cnn2-c1ccc(F)cc1 +CCOC(=O)C(NC(=O)Nc1ccccc1)C(F)(F)F +CCSc1cc(C(=O)N(C(C)C)C2CC2)ccn1 +O=C(Nc1nc2c(s1)CNC2)c1cccc(F)c1 +CCn1c(CNc2ncnc(SC)c2C#N)nc2ccccc21 +Cc1ccc(-c2csc(SCC(=O)Nn3cnnc3)n2)cc1 +CCC1(c2ccccc2)Nc2ccccc2C(=O)N1C +CC(Sc1ccccc1)C(=O)Nc1cccc(N2CCCC2=O)c1 +Cc1ccc(SCCN2CC(C)OC(C)C2)cc1 +Cc1ccc(-n2nnc(C(=O)NC(C)C)c2C)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)N(C)C(C)c1ccccn1 +O=C(c1cccnc1)N1CCN(c2nnnn2-c2ccccc2)CC1 +CC(NS(=O)(=O)c1sccc1Br)C(N)=O +CC1CCCN(S(=O)(=O)N2CCC(C(N)=O)CC2)C1 +C=CCCOCCNC(=O)C1COc2ccc(F)cc2C1 +Cc1nc(CN2CCc3ccc(Cl)cc3C2)cs1 +O=C(Cn1nc2c(cc1=O)CCCCC2)Nc1ccncc1 +Cc1ncsc1CCC(=O)NCc1n[nH]c(N)n1 +O=C(NCc1ccccc1F)c1cc2ccccc2c(=O)[nH]1 +CC(c1cccc(Cl)c1)N(C)C(=O)CNC(=O)c1ccsc1 +O=C(NC1CCN(c2ccc(F)cc2)C1=O)c1ccccc1F +COc1cc(CNC(=O)c2ccsc2)ccc1OCC(N)=O +CC(NC(=O)NC1CCCN(c2ncccn2)C1)c1cccnc1 +Cc1c(C(=O)OC(C)C)sc2ncn(C)c(=O)c12 +CC(C)CC(C#N)NC(=O)c1cccc(S(C)(=O)=O)c1 +O=C(NC1CCCCC1)C1OC(CCN2CCOCC2)CCC1O +Cc1cc(Cl)ccc1S(=O)(=O)NCc1nccn1C(F)F +Nc1cnn(CCCOc2cc(Cl)cc(Cl)c2)c1 +Cc1cccc(NC(=O)c2ccc(Cn3cncn3)cc2)c1 +Cc1ccsc1C(=O)N(C)CC(=O)Nc1c(C)cccc1C +NS(=O)(=O)c1ccc(CNC(=O)c2ccc[nH]c2=O)cc1 +CC(NC(=O)C1CC1c1ccc(Cl)cc1)C(N)=O +C=CCNC(=O)c1cnn2c(-c3cccs3)ccnc12 +CC(=O)N(C)CC(=O)Nc1cnc(N2CCCC2)nc1 +Cc1cccc(-c2nc(CNC(=O)C3CC3)no2)c1 +COc1cccc(-n2cnnc2SCC(=O)N2CCCCCC2)c1 +COc1ccc(OC)c(C(C)NC(=O)c2cnccn2)c1 +NC(=O)Cn1cc(C(=O)NC(c2cc3ccccc3o2)C2CC2)nn1 +O=C(c1ccc(CO)cc1)N1CCCCC1c1ccc(F)cc1 +CC(Cc1cccs1)NC(=O)c1ccc(Br)cn1 +COc1ccc(NC(=O)C23CCC(C)(C(=O)O2)C3(C)C)cc1 +Cc1csc(S(=O)(=O)C(C)C(=O)NC2CCCCC2)n1 +CCN1CC2(CCCN(C(=O)c3cccc(C)c3O)C2)CCC1=O +Cc1c(C(=O)NC(C)CCC2CCCC2)cnn1-c1ccncc1 +Cc1cc(=O)[nH]c(SCC(=O)N2CCCC2c2ccccn2)n1 +CC(C)NC(=O)NCC1OCC(NCc2cccs2)C1O +COc1cc(CNC(=O)c2c[nH]c3ccccc3c2=O)ccn1 +CCOc1ccc(OC(=O)C2CCOc3ccccc32)cc1 +Cc1sc(-c2ccncc2)nc1-c1ccc2c(c1)CCN2 +CCC(=O)Nc1nc2ccc(NC(=O)NCCCOC)cc2s1 +Cc1nc(-c2ccccc2)ncc1C(=O)Nc1ccc(F)cc1F +O=c1[nH]c(SCCCO)nc2cc(Cl)ccc12 +COC(=O)COc1nc2n(c(=O)c1Cc1ccccc1)CCS2 +O=C(NCC1CCOC1)c1ccc(Cl)cc1F +COc1cc(C(=O)N2CCC(CO)CC2)cc(OC)c1C +CSc1ccc(C(O)CNC(=O)c2ccoc2)cc1 +COCCN(CC(=O)N(C)C)C(=O)c1oc2ccc(OC)cc2c1C +COc1cc(C)c(-c2nc(Cn3cncn3)c(C)o2)cc1C +O=C(Nc1ccncc1)c1ccc(OCC(F)(F)C(F)F)nc1 +NC(=O)c1csc(C(=O)OCc2nc3ccccc3s2)c1 +NS(=O)(=O)c1cc(C(=O)OCC(=O)c2ccc[nH]2)ccc1Cl +CCC1(O)CCN(C(=O)c2cc(OC)c3ccccc3n2)CC1O +COCC(=O)N1CCC2(CC(=O)N(c3ccccc3)C2)C1 +CCc1nc2ccccc2n1CC(=O)Nc1cnc2ccccc2c1 +O=C(Cc1ccc(F)c(F)c1)Nc1ccccc1O +CCCCN1C(=O)COc2c(OCCC)cc(CO)cc21 +COC(=O)NCC(=O)Nc1cc(Cl)ccc1OC +C#CCOCC1CCN(C(=O)Nc2ccccc2)CC1 +CC(c1cccnc1)N1CCN(C(=O)C2(C)CC2(Cl)Cl)CC1 +CCCCOC(=O)CN1C(=O)C(C)(C)Oc2ccc(C(C)=O)cc21 +CN(CC(=O)OCC1CCCCC1)C(=O)c1cccs1 +COCC(=O)Nc1ccccc1CC(=O)N(C)C +COc1ccc(NC(=O)Cc2cccc(C)c2)cc1OC +NS(=O)(=O)c1ccc(NC(=O)NCc2ccoc2)cc1 +CCc1c(C(=O)NC2CCC(CO)CC2)cnn1-c1ccc(C)cc1 +Cc1cccc(OC2CCN(c3nc(N)nc4[nH]cnc34)CC2)c1 +Cc1cc(C(=O)Nc2ccc(OC(F)F)cc2)no1 +Cc1cc(C(=O)NCCc2n[nH]c(=O)[nH]2)c2cccc(C)c2n1 +Cc1noc(C(C)C)c1C(=O)NCCc1nc2cc(F)ccc2n1C +O=C(NCCNC(=O)c1ccnc2ncccc12)Nc1ccccc1 +CCC1Oc2cc(CO)ccc2N(C(C)C(C)=O)C1=O +O=C(c1cnccn1)N1CC2OCC(=O)N(Cc3ccncc3)C2C1 +COc1ccc(-c2nnc(C(=O)NC3CC3)n2C)cc1 +CCCOC(=O)c1cc(-c2cc(Cl)ccc2O)n[nH]1 +CC(=O)Nc1cccc(NCC(=O)Nc2ccc(F)cc2)c1 +CCCCc1nnc(NC(=O)Cc2cccc(OC)c2)s1 +Cc1nc(C)c(CCC(=O)N2CCCC2C2CCCCC2)c(=O)[nH]1 +O=C(CNC(=O)c1ccnc2[nH]ccc12)Nc1cccc(Cl)c1 +CN(CC(=O)N1CCOCC1)C(=O)Cc1cccc(F)c1 +CN(Cc1ccc(Cl)cc1)c1nccc(N2CCOCC2)n1 +COc1ccc(C(=O)OCCCc2cccnc2)cc1F +Cc1ccnc(NCC2(COc3ccccc3)CC2)n1 +COC(=O)C1CN(CC(=O)NC2CCCCC2)c2ccccc2O1 +Nc1ccc2c(c1)N(C(=O)c1ccc(Cl)c(Cl)c1)CC2 +CCOC(=O)c1ccc(CNC(=O)c2c(Cl)cccc2Cl)o1 +CCOc1ccc(-n2nnnc2CNC(=O)Cc2cccs2)cc1 +COc1ccc(CN2CCCC(c3nncn3C)C2)cc1SC +Cc1cccc(C(=O)NC(C(=O)Nc2cc[nH]n2)C(C)C)c1 +CC1Sc2ccc(C(=O)Nc3ccccc3Cl)cc2NC1=O +Cc1nn(C)c(=O)c(C(=O)N(C)CCOc2ccccc2F)c1C +CCn1c(NC(=O)CCc2nc3ccccc3[nH]2)nc2ccccc21 +CCNC(=O)CCCc1nc(-c2ccc(C)cc2)no1 +NC(=O)C(NCC(F)(F)F)c1cc(Br)ccc1F +Cc1cc(C)nc(SCC(=O)NC(C)c2ccc(F)cc2F)n1 +CCNC(=O)CNC(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +C=CCNC(=O)Nc1ccc(S(=O)(=O)N2CCC(C)CC2)cc1 +Clc1ccc(NCc2noc(C3COc4ccccc4O3)n2)cc1 +CCc1cc(NCCS(=O)(=O)N(C)C)ncn1 +CCN(C(=O)Nc1nc(C)c(C)o1)C(C)c1cccc(O)c1 +CC(=O)N1CCCc2cc(S(=O)(=O)N(C)CCO)ccc21 +Cc1cc(C)cc(-n2ccnc2SCc2cncn2C)c1 +Cc1ccc(N2CCCN(C(=O)CCn3nc(C)cc3C)CC2)nn1 +CCc1nnc(NC(=O)c2cccc3c2OCCO3)s1 +Cc1cc(=O)c(O)c(CN2CCN(CCO)CC2)n1C +Cc1ccc(S(=O)(=O)N(C)CC(=O)Nc2sccc2C#N)cc1 +CCOC(=O)CNC(=O)Sc1ccc(Cl)cc1 +O=C(Cc1ccc[nH]1)NC1CCN(c2ccc(Br)cc2)C1 +CCOC(=O)CC(C)CNC(=O)c1ccc2[nH]cnc2c1 +NC(=O)c1ccn(-c2ccccc2NC(=O)c2cc(Cl)ccn2)n1 +Cn1nc(C(C)(C)C)cc1NC(=O)Cn1ccccc1=O +Cc1ncsc1C(=O)N(C)Cc1ccsc1 +Cc1cc(NC(=O)COC(=O)C2(c3ccc(Cl)cc3)CC2)no1 +Cc1cc(C(=O)NC2C3CC4CC(C3)CC2C4)c2c(C)noc2n1 +CC1(c2c(Cl)ccc(F)c2Cl)COCCN1 +COc1cc(F)c(C(C)NC(=O)c2ccccc2F)cc1OC +CN(C(=O)c1ccc(-n2cccn2)cc1)c1ccccn1 +CCOC(=O)c1ccc(NC(=O)c2cccc(OC(C)=O)c2)cc1 +CCc1onc(C)c1NC(=O)NC(C)CC(C)C +CN(Cc1ccccc1F)C(=O)CCNC(=O)c1ccco1 +Cc1ccc(S(N)(=O)=O)cc1C(=O)OCc1ccc(C(N)=O)cc1 +CC(C)(C)C(=O)Nc1ccc(S(N)(=O)=O)cc1 +Cc1ccc2oc(=O)c(CC(=O)CC(C)C)nc2c1 +CC1Cc2c(sc3nc(-c4ccccn4)nn23)CN1 +Cc1ocnc1C(=O)NC1CCCN(c2ccccc2F)C1=O +COCCN(Cc1cc(F)cc(F)c1)Cc1ccc(C)o1 +NC(=O)N1CCC(NC(=O)c2ccc(C3CCCCC3)cc2)CC1 +Nc1ncnc(Nc2ccccc2C(F)(F)F)c1N +O=C(CCNC(=O)Nc1cn[nH]c1)NC1CCCCC1 +NC(=O)c1c(N2CCC2=O)sc2c1CCCC2 +CCOc1ccc(OCC(=O)Nc2ccc(OC)c(N)c2)cc1 +O=C(Nc1ccncc1)C1(c2cccc(Cl)c2)CCOCC1 +CCc1cc2c(=O)n(CCOc3ccc(OC)cc3)cnc2s1 +Cc1cccc(NC(=O)CCNC(=O)C2CC2c2ccc(C)s2)n1 +C=CCN(CC=C)C(=O)c1cn(Cc2ccccc2F)nn1 +CCCCCNC(=O)Nc1ccc(OC)c(N2CCCCC2=O)c1 +CCOC(=O)c1cn(CC(F)(F)F)nc1-c1ccc(OC)cc1 +COc1ccc(C)cc1NC(=O)NC1c2ccccc2CC1O +Cc1nc(C(=O)OCc2nc3ccccc3[nH]2)cs1 +COCCCCNC(=O)c1csc(NC(C)=O)n1 +O=C1CN(C(=O)Nc2nnc(C3CCCCC3)s2)CCN1 +CCOC(=O)CN(C)C(=O)Cc1ccccc1O +Cc1nc(CN2CCN(S(=O)(=O)CCC(C)C)CC2)no1 +Cn1nnc2cc(CNC(=O)c3cccc(Cl)c3)ccc21 +Nc1nccnc1C(=O)Nc1cccc(COc2cccc(F)c2)c1 +COc1ccc(N(C)C(=O)c2scnc2C2CC2)cc1Cl +Cc1cc(C(=O)NCCC(=O)NCc2ccncc2)c(F)cc1F +Cc1ccc2c(NC(=O)c3cccnc3)cccc2n1 +O=C(Nc1ccc2nc(N3CCCC3)sc2c1)c1ccccn1 +CCOC(=O)c1sc2nc3cc(OC)ccc3cc2c1N +CC(=O)c1nnn(-c2ccccc2)c1NCc1ccccn1 +Cc1ccc(NC(=O)C(NC(=O)c2ccccc2)C(C)C)cc1 +O=C(CSc1nnc(-c2cccnc2)o1)c1ccccc1 +Cc1c(Cl)cccc1-n1c(=O)c(N)c(C)n1C +Cc1ccc(NC(=O)c2ccncc2)cc1S(=O)(=O)NC1CC1 +CS(=O)(=O)N1CCCC(NC(=O)c2cc3c(cc2O)OCO3)C1 +O=C(Cc1ccc[nH]1)NCC1(c2cccc(Cl)c2)CCOCC1 +CCOC(=O)CN(CC)S(=O)(=O)c1sc(=O)[nH]c1C +CN(C)S(=O)(=O)c1cccc(C(=O)NCC2CCCO2)c1 +CCOc1ccc(NC(=O)NCc2ccc(OC)nc2)cc1F +Cc1cc(C)c2c(NCc3cccc(F)c3)n[nH]c2n1 +COc1ccc(CCC(=O)N2CCCC2c2cc(C)no2)cc1 +COc1ccc2ncnc(N3CCN(Cc4ccccc4)CC3)c2c1 +CCCC(=O)Nc1ccc2c(c1)nc(CCN1CCCCC1=O)n2C +CC1(C(=O)N2CCOCC2)CN(Cc2ccc3cc[nH]c3c2)CCO1 +Cc1cc2ccccc2n1CC(=O)Nc1cnn(CC2CCCO2)c1 +O=S(=O)(NCc1ccccn1)c1ccc2c(c1)CNCC2 +CCN(CC)c1nc(-c2csc(NC(C)C)n2)cs1 +Cc1nc(C)c(CC(=O)N2CCC2c2cccs2)s1 +Cc1cccc(CNc2c(C)cc(O)cc2C)c1C +CC(C)c1cc(C(=O)NCCCn2ccc3ccccc32)n(C)n1 +Cc1cc(OCC(=O)c2c[nH]c(C(=O)N3CCCC3)c2)ccc1Cl +COc1ccccc1C(C)N(C)C(=O)Nc1nc(C)cs1 +Cc1c(NC(=O)N2CCCC2(C)CO)cccc1OCC(F)(F)F +CN(CC1CCCN(C(=O)OC(C)(C)C)C1)c1ncc(F)cn1 +Cc1nn(C)c2ncnc(N3CCC4(CCCN(C)C4=O)C3)c12 +COCCCNC(=O)Cn1nc(-n2nc(C)cc2C)ccc1=O +Cc1ccc(S(=O)(=O)N(C)c2ccc3c(c2)NC(=O)C3)cc1 +CC(C)C(=O)NCCNC(=O)CNC(=O)c1cccs1 +CCC(C)(C(=O)NCc1cccc2ccccc12)N1CCC1=O +O=C(NCCc1nc2ccccc2[nH]1)C1COc2ccc(F)cc2C1 +Oc1cccc(C2Nn3c(nnc3-c3ccccc3)S2)c1 +CCCc1oncc1C(=O)N1CCC(CCn2cccn2)CC1 +O=C(COc1cccnc1)NCCn1nc(-n2cccn2)ccc1=O +COc1ccc(CNC(=O)N2CCCC(O)C2)c(OC)c1 +Cc1nn(-c2ccccc2)c(C)c1-c1n[nH]c2cccc(N)c12 +Cc1cccc(CNC(=O)NCC(=O)N2CCc3ccccc32)c1 +COC(=O)CCCN(C)S(=O)(=O)c1cn[nH]c1C +CCCC(=O)NCC(=O)NC1CCCC(C(F)(F)F)C1 +Cn1cc(NC(=O)C(NC(=O)c2ccccc2)c2ccccc2)cn1 +OC1CCN(c2ncc(-c3ccc(OC(F)(F)F)cc3)cn2)CC1 +CCOC(=O)c1cn2nc(-c3cccs3)cc2[nH]1 +NC(=O)CN(Cc1ccc(-c2ccccc2)cc1)C(=O)C1CCCO1 +CNC(C)C(=O)c1cc(Br)ccc1OC +C=CCCOC(=O)C1CCCN(C(=O)Nc2ccccc2)C1 +O=C(Nc1ccccc1)C1(n2cnnn2)CCCCC1 +CNC(=O)C(C)CN(C)C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +CCN1CC(c2nc(-c3ccc(OC)nc3)no2)CC1=O +CCCC(=O)NC(c1ccccc1)c1nnc(N2CCOCC2)o1 +NC(=O)C1CCN(c2ncccc2C(F)(F)F)CC1 +Cc1nc(-c2ccc(S(=O)(=O)NCC3CC3)s2)cs1 +CCC(O)CN(Cc1cc(=O)n(C)c(=O)n1C)c1ccccc1 +COc1ccccc1CN(Cc1cccs1)C(=O)c1cc(C)on1 +COC(=O)N(C)CC(=O)Nc1ccccc1OC +Cc1noc(C)c1CCC(=O)OC(C)c1cccc(F)c1 +Cc1cccc(NC(=O)C(c2ccccc2)c2ccccc2)n1 +Cc1cc(OCCn2ccc(N)n2)cc(C)c1Cl +COc1ccccc1-n1nc(C2CC2)nc1-c1ccncc1Cl +CCC(C)NC(=O)C(Sc1nccn1C)C(C)C +Cc1ccc2oc(C(=O)NCCCC(N)=O)cc2c1 +COC(=O)C(NC(=O)c1ccc(SC(F)F)cc1)C(C)C +Cc1nc(NC(=O)c2ccn(C)n2)sc1C(=O)N(C)C +CC(C)NC(=O)N1CCCC(O)C(NC(=O)c2ccc(O)cc2)C1 +CCOC(=O)Cc1csc(CNC(=O)c2ccccc2)n1 +Cc1cc(-c2cc(C(=O)OC(C)C)n(CCO)n2)ccc1Cl +Cc1nnc(C23COCC2CN(C(=O)c2ocnc2C)C3)o1 +CCNC(=O)c1cc(Cl)ccc1NCc1cccc(OC)c1 +Nc1c(C(=O)Nc2ccccc2F)oc2ccccc12 +CC(=O)c1ccc2c(c1)N(CC(N)=O)C(=O)C(c1ccccc1)O2 +COc1c(C)cc(Cl)cc1C1NCCN(C)C1=O +Cc1nc(C)c(S(=O)(=O)NC2CCCCC2)s1 +CSc1ccc(NC(=O)NC2CCN(c3ccccc3)C2=O)cc1 +O=C(CNC(=O)NCC1(c2ccc(Cl)cc2)CCCC1)NC1CC1 +Cn1cnc(-c2cccc(NCc3csnn3)c2)n1 +O=C(COc1nncc2ccccc12)NCCc1ccc(F)cc1 +CCn1c(=O)sc2cc(NS(=O)(=O)c3ccc(C)cc3)ccc21 +CNC(=O)c1c(NC(=O)c2ccccc2C)sc(C)c1C +Cc1ccc2ncc(C(=O)Nc3c(C)cccc3C)c(=O)n2c1 +CCOC(=O)N1CCN(C(=O)c2ccccc2NC(=O)COC)CC1 +CCS(=O)(=O)c1cccc(C(=O)Nc2nnc(-c3ccno3)o2)c1 +Cc1nnc(N2CC3COCC(C(=O)Nc4cnccn4)C3C2)s1 +CC(CO)(NC(=O)Nc1cccnc1-n1cncn1)C1CC1 +Cc1cccc(NC(=O)NCC(=O)N(C)Cc2cccc(C#N)c2)c1 +Cc1nn(Cc2ccc(Br)cc2)c(C)c1O +CNC(=O)c1ccc(OC)c(NC(=O)Cc2ccc(C)s2)c1 +CCN(C(=O)CCCc1cc(F)ccc1F)c1cccnc1 +COc1cccc(OC)c1CNc1nnc(C)s1 +O=C(CNC(=O)OCC(F)(F)F)Nc1nccs1 +CN1C(=O)CCC(C(=O)NCc2cccc(F)c2)C1c1cnn(C)c1 +Cc1cc(Cl)ccc1NC(=O)c1ccc(S(N)(=O)=O)cc1 +N#CC1(NC(=O)c2ccc(Br)cc2Br)CC1 +Cc1nc(C(=O)NC(C)(C)C)nn1-c1ccccc1Cl +O=C(C1COc2ccccc2O1)N1CCCc2ccccc21 +CCn1c(SCc2noc(CC(C)C)n2)nnc1C1CC1 +Cc1cnc(C(=O)Nc2ccc(N3CCCCC3)nc2)cn1 +O=C(NCC#Cc1ccccc1)NC1CCSc2ccccc21 +Cc1ccc(S(=O)(=O)C2(C(=O)Nc3ccc(C)cn3)CCC2)cc1 +Cn1cc(C(=O)NCc2ccccc2)c(=O)c2c(N)cccc21 +Nc1cccc(OCCNC(=O)C2CCCO2)c1 +COc1ccc(C(=O)CCNc2ccccc2C)cc1N +Cc1ncc(CNC(=O)c2cccnc2Nc2cccc(F)c2)s1 +COc1ccc(C(=O)COc2ccccc2N)cc1Cl +CC(C)CNS(=O)(=O)c1ccc(Br)cc1 +CCC(=O)Nc1cccc(NC(=O)NC(C)c2ccncc2)c1 +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)NCCc1ccco1)O2 +CC(C)Oc1ccc(CNC(=O)C2CCC(=O)N2)cc1F +Cc1c(NC(=O)c2ccncc2)cccc1C(N)=O +O=C(COc1ncnc2ccccc12)NC1CCCCC1 +O=C(CSc1nncn1-c1ccccn1)c1ccc(F)cc1 +Cc1ccc(C(C)C)c(OCc2nn3c(=O)c(C)nnc3s2)c1 +CN(C)C(=O)CCC(C#N)c1ccccc1Br +Cc1cccc(NC(=O)c2cnn(-c3ccncc3)c2C)c1C(N)=O +O=C(NC1CCCCC1)c1n[nH]c2c1CN(C(=O)c1ccno1)CC2 +Cc1ccc(NC(=O)CSc2nncn2C)cc1F +COCCCS(=O)(=O)NC1CCCN(c2ccccc2F)C1=O +Cc1c(C(=O)NCCc2c(F)cccc2F)cnn1-c1ccncc1 +COc1ccc(N)cc1-n1cc(-c2ccccc2)nn1 +Cc1cccc(-c2ncc(C(=O)N3CCOCC3)c(=O)[nH]2)c1 +CC(C)C(NS(=O)(=O)c1cccnc1)c1nnc2ccccn12 +COC(=O)CNC(=O)N1CCn2cccc2C1Cc1ccccc1 +Cc1nc2ncccn2c1C(=O)NCCNC(=O)c1cccnc1 +Cc1onc(C(=O)NCc2cccc(Cl)c2)c1CN1CCOCC1 +CN(Cc1ccsc1)C(=O)NCC1CN2CCCCC2CO1 +Cc1ccc(CC2(NC(=O)C(C)N3CCCC3=O)CC2)cc1 +O=C1CN(S(=O)(=O)c2ccc3oc(=O)ccc3c2)CCN1 +COc1ccc(F)cc1C(=O)C1CCCN1C(=O)C(C)(C)C +O=C(CCCn1cccn1)N1CCC(c2ccc(O)cc2)CC1 +CC(CO)C(C)NC(=O)NC1CCN(c2ccccc2Cl)C1=O +Cc1cccn2c(F)c(C(=O)N3CC4CCC(C3)N(C)C4=O)nc12 +CC(=O)Nc1nc2c(c(NC(C)=O)n1)CC(O)CC2 +CCOCCNC(=O)c1ccnc(-n2cncn2)c1 +Cc1cnc(C(=O)N2Cc3cnn(Cc4ccc(F)cc4)c3C2)cn1 +CCCNC(=O)C(C)Sc1nnc(-c2ccccc2OC)n1N +COC(=O)NCCC(=O)NCC(C)(C)c1ccc(F)cc1Cl +Cc1ccc(-c2cc(C(=O)NCCN3CCOCC3)no2)cc1 +Cc1cccc(OCCNC(=O)Nc2nncs2)c1 +CN(Cc1ccsc1)c1ncnc2c1cnn2CCC#N +Nc1ccc(Cl)cc1NC(=O)Cc1cccs1 +CCOc1ccccc1OCCn1nc2ccccc2n1 +O=C(CCC1Cc2ccccc2NC1=O)NCCN1CCOCC1 +Cc1nccn1-c1ccc(NC(=O)C23CC4CC(CC(C4)C2)C3)cn1 +O=C(NCC1CCCOC1)c1ccc(-c2ccccc2)[nH]c1=O +Cc1cccc2nnc(N3CCC(C(=O)N4CCC(C)CC4)CC3)n12 +COc1ccc(-n2cnc3c(oc4ccccc43)c2=O)cc1 +CCn1nc(C)c2c(C(=O)NCc3ccco3)cc(C)nc21 +Cc1n[nH]c(C)c1NC(=O)CCNC(=O)C(C)(C)C +CCOc1ccc(C(=O)CSc2cccc(N)c2)cc1 +CCN(CC(=O)Nc1cccc(C(=O)N(C)C)c1)c1ccccc1 +CCN(CC)S(=O)(=O)c1ccc(F)c(OC)c1 +Cc1ccc(NC(=O)c2ccc(S(=O)(=O)NC3CC3)o2)nc1 +Cc1ccc(NC(=O)c2ccnc(N(C)C)c2)nc1 +Cc1oc(-c2ccccn2)cc1-c1nnc(NC(C)C)s1 +CN(c1ccccc1)c1nc(=O)c2cc3ccc(=O)oc3cc2o1 +COc1nccc(N2CC3C4CCC(O4)C3C2)c1C#N +CC(C)(C)OC(=O)N1CCC(n2cc(N)cn2)C1 +CS(=O)(=O)N1CCN(Cc2nnnn2-c2ccccc2)CC1 +CCN(CCO)C(=O)CCc1c(C)nc2c(C(N)=O)cnn2c1C +COc1cccc(NC(=O)c2c[nH]c3ccc(F)cc3c2=O)c1 +O=C(NCCN1CCCCCC1=O)c1ccc(Cn2cncn2)cc1 +Cc1nc(C2(NC(=O)c3cccc(-c4ccoc4)c3)CCCC2)no1 +Cc1ccccc1OCC(=O)OCC(=O)c1ccc2c(c1)OCO2 +Cc1ccc(-n2cc(S(=O)(=O)NCc3cccnc3)cn2)cc1 +Cn1ncc(C(=O)NCCc2nc3ccccc3[nH]2)c1-n1cccc1 +O=C(NCc1cc[nH]n1)N1CCN(Cc2cccs2)CC1 +C=C(C)C1CCC(C)=C1COC(=O)c1cccnc1 +Cc1ccc(C)c(S(=O)(=O)NCCC(N)=O)c1 +CC(CO)NC(=O)Cn1c(SC(F)F)nc2ccccc21 +COCC1CCCC12CN(Cc1ccc(F)cc1)CCO2 +CCCCOC(=O)C(C)Sc1ccccc1N +O=C(Cn1nc(-c2ccc(F)cc2)oc1=O)c1ccco1 +O=c1c2ccccc2nc(C=Cc2csnn2)n1-c1ccccc1 +COC(=O)CC1CCCCN1C(=O)Cn1cccn1 +Nn1c(SCc2cccc(F)c2)nnc1-c1ccco1 +O=C(Nc1ccc(F)cc1)N1CCN(C(=O)C2CCCO2)CC1 +CN1CCOC(c2noc(-c3ccc4ncccc4c3)n2)C1 +COCC(=O)N1CCC(c2cc(Nc3cnccn3)nc(C)n2)C1 +Cc1cccn2cc(CC(=O)N3CCCC(C(F)(F)F)C3)nc12 +O=C(c1ccc(Cl)cc1Cl)N1CCCC1CCCO +CN(CCO)C(=O)c1ccc2c(c1)N(C)C(=O)CCO2 +O=C(Cc1ccccc1O)Nc1ccc2[nH]c(-c3ccccn3)nc2c1 +COC(=O)C(CC(C)C)NC(=O)c1ccc(C)c(NC(C)=O)c1 +CCN(CC)C(=O)CCn1nc(-c2ccccc2)c2ccccc2c1=O +Cc1ccc(C)c(S(=O)(=O)CCN2CCn3c(C)nnc3C2)c1 +O=C(Cc1ccc[nH]1)NCCCC(=O)Nc1ccc(Cl)cc1 +Cn1cccc1C(=O)CN1C(=O)c2ccccc2S1(=O)=O +O=C1c2nc3cc(F)c(F)cc3nc2CN1C1CCCCC1 +Cc1cc(C(=O)COc2ncnc3sccc23)c(C)n1C +CC(C)N(C)c1ccc(NS(=O)(=O)c2cccc(C#N)c2)cc1F +COc1cc(C(=O)N(Cc2ccsc2)C2CC2)cc(OC)c1OC +Cc1cc(Br)ccc1NC(=O)CCO +CC(C)Oc1ccccc1C1CC2(C)NC(=O)C1C(=O)N2 +CC(C)COc1ccc(CNC(=O)N2CCOCC2C)cc1 +Cc1cc(N2CCN(C(=O)CC3C=CCC3)CC2)nc(C(C)C)n1 +O=C(NCc1ccccc1F)C1CCN(c2cccc(Cl)c2)C1=O +CN1CCN(C2CCN(c3c(C#N)c(=O)n(C)c(=O)n3C)CC2)C1=O +CCOc1cc(C(N)=O)ccc1OCc1ccncc1 +CC(C)CCN1CN(n2cnnc2)Cn2c1nc1ccccc12 +CC(CCCO)NC(=O)N1CCCC(CN2CCOCC2)C1 +CC(=O)Nc1ccc(NCc2noc(CC(C)C)n2)c(Cl)c1 +O=C(c1ccc(F)cc1)N1Cc2nc(-c3ccccc3)sc2C1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCC2CCCC(O)C2)n1 +Cc1ccccc1N1CCC(C(=O)NC(C)c2ccccc2)C1=O +OC(COCC1CC2CCC1C2)CN1CCOCC1 +CC1(C)CC(=O)c2cnc(NCCc3ccco3)nc2C1 +O=C(Nc1ccc(O)cc1)c1cccn2c(-c3ccccc3F)nnc12 +COc1cc(CNC(=O)NCc2ccco2)ccc1C +Cc1occc1C(=O)NCC1CN2CCCCC2CO1 +COc1ccccc1Nc1ncccc1C(=O)N(C)Cc1cccnc1 +Nc1ccc2c(c1)CN(C(=O)c1ccc(Cl)cc1)CC2 +Cc1ccc(C)c(C(=O)CCC(=O)NC(C)c2nc3ccccc3[nH]2)c1 +CC(=O)Nc1cccc(NC(=O)CNC(=O)C(C)(C)C)c1 +CCOC(=O)C1=C(C)OC2C1N(C(C)=O)c1ccccc1N2CC +O=C(c1ccccn1)N1CCC(Oc2nncc3ccccc23)CC1 +CNc1ncc(C(=O)N(CCOC)C2CC2)cc1Cl +O=C1CCC2(CCCO2)CCN1Cc1cccc(F)c1 +Cc1ccc(C(=O)N(C)C)cc1OCc1cccc(C(N)=O)c1 +Cc1n[nH]c2c1C(c1ccc(OC(C)C)cc1)CC(=O)N2 +Cc1ncc(CNC(=O)c2cc3ccc(Cl)cc3[nH]2)s1 +Cc1noc(CSc2nnc(C3COc4ccccc4O3)o2)n1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(F)c(F)c2)cc1 +COc1ccc2c(C)c(Br)c(=O)oc2c1N +CC(c1ccccc1F)N(C(=O)Nc1nccs1)C1CC1 +CCOc1ccccc1-n1nnc(C#N)c1C1CCCO1 +COc1ccc(Br)c(C(=O)NCC2CC2C)c1 +CCc1nc(COC)cc(OCC(=O)Nc2nccs2)n1 +CCCC(=O)N1CCC(C(=O)NC(CC)C(O)C(F)(F)F)CC1 +CCC(CC)c1nnc(NC(=O)NCc2ccnn2C)s1 +COc1nccnc1COC1CCN(C(=O)OC(C)(C)C)C1 +Cc1noc(C)c1CNc1cc(C(N)=O)ccc1F +Cc1ccc(C(=O)NCc2c(C)nn(C)c2C)c(-n2cnnn2)c1C +CC(=O)N(CCc1ccccc1)CC(=O)Oc1ccc(F)cc1C +O=C(OCCc1c[nH]nc1C(F)(F)F)c1cccc2c1OCCO2 +COC(=O)c1cncc2c(O)n(-c3ccccc3)nc12 +Cc1nccn1-c1cncc(NCCCn2cnc3ccccc32)n1 +CC(C)COc1ccccc1NC(=O)NCc1nnc2n1CCC2 +Cc1ccccc1CNS(=O)(=O)c1ccc2c(c1)OCCO2 +Nc1nc(-c2cnccn2)c(Br)c(=O)[nH]1 +COC(=O)c1ccc(NC(=O)c2cccc(C(=O)OC(C)C)n2)cc1 +Cn1c(=O)c2[nH]c(C3CC4CCC3C4)nc2n(C)c1=O +CC(C)NC(=O)Cc1ccc(NC(=O)Nc2nccs2)cc1 +NC(=O)Cn1c(=O)oc2cc(Br)ccc21 +O=C(NCC(F)F)N1CCOC(Cc2ccccc2)C1 +Cc1ccc(C(C)(C)C)c(OCCC(=O)N2CCNCC2)c1 +FC(F)(F)Oc1ccc2c(c1)CCNC2c1ncccn1 +CCCNC(=O)CNC(=O)c1cccnc1NC +Cc1cccc2sc(NC(=O)CCn3cccc3)nc12 +CCCOCCNc1nc(C)nc2oc(C)nc12 +O=C(COc1ccccc1)NCCn1ncccc1=O +CSc1ncccc1C(=O)Nc1ccc(F)cc1C +CCN(CCC#N)C(=O)CNc1ccc2oc(=O)n(C)c2c1 +CC1(c2nc(C3CCOC3)no2)CCCN1C(=O)c1ccccc1 +CCOC(=O)N1CCN(CC(=O)Nc2cc3c(cc2C)OCO3)CC1 +Cc1nc2c(c(=O)n1C)CN(C(=O)C1CCCN(C(=O)N(C)C)C1)C2 +CC1CN(C(=O)COc2ccc(F)cc2Cl)CC(C)O1 +COc1ccccc1C(O)CCC(=O)NC1CCCCCC1 +COc1ccccc1CNC(=O)NC(C1CC1)C1CC1 +COc1cc(F)c(COC(=O)C2CCCN2)cc1F +COc1ccccc1C1CC1NC(=O)c1cc(=O)c2ccccc2o1 +CC(C)=CCC1(CO)CCCN(C(=O)CCCc2cn[nH]c2)C1 +CCOC(=O)CCc1c(C)[nH]c2nc3ccccc3n2c1=O +CCNS(=O)(=O)c1ccc(C)c(C(=O)Nc2cc(C)cc(C)c2)c1 +COC(=O)CNC(=O)Cc1c(C)nc2ccccc2c1-c1ccccc1 +O=C(NCc1nn(Cc2ccccc2)c2ccccc12)c1cnccn1 +COCC(=O)NC(C)c1ccc(C(F)(F)F)cc1 +CCC(C)(C)NC(=O)c1ccc(NCC(=O)N(C)C2CC2)cc1 +CCOC(=O)c1cnn(C2CCCN(C(=O)C3C(C)(C)C3(C)C)C2)c1 +CSc1nsc(NC(=O)N2CC(C)CCC2C)n1 +Cn1cccc1C(=O)NCCc1ccc(F)c(Br)c1 +COc1ccc(C(=O)NCc2ccnc(Oc3ccccc3)c2)cc1 +Cc1occc1C(=O)OCC(=O)c1cc(C)n(CC2CCCO2)c1C +O=C(CN1C(=O)COc2ccc(Cl)cc21)Nc1cn[nH]c1 +Cc1cccc(C(=O)N2CCN(Cc3ccsc3)CC2)c1 +CCOC(=O)C(C)N1CCC2(CCC1=O)NC(=O)c1cccnc1N2 +Cc1nc(CN2C(=O)COC3CN(S(C)(=O)=O)CC32)cs1 +CCc1c(CO)nnn1CCOc1cccc2ccccc12 +COc1ccc(C(=O)Cn2cnc3c2c(=O)[nH]c(=O)n3C)cc1OC +Cc1cc(C)n2cc(CN(CCC#N)CCC(F)(F)F)nc2n1 +CCC(C)NC(=O)CNc1ccc(C(=O)NC(C)C)cc1 +Cc1occc1-c1nnc(SCCOc2cccc(C#N)c2)n1C +O=C(COc1ccccc1O)Nc1ccc(OC(F)F)cc1 +COc1cc(C(C)NC(=O)NCc2ncn(C)n2)ccc1OC(C)C +Cc1cccc(Oc2ccc(NC(=O)Cn3cnc(C#N)n3)cc2)c1 +COC(=O)c1ccccc1OC(=O)Cc1c(C)noc1C +CCOc1ccc(CCC(=O)Nc2nccs2)cc1 +O=C(CN(Cc1c(F)cccc1F)CC1CCCO1)N1CCCC1 +Cc1cccc(OCC(=O)Nc2cccc(-n3c(C)c[nH]c3=O)c2)c1 +CCOc1ccc(C2CCCN2C(=O)CCNS(C)(=O)=O)cc1 +CCC(C)NC(=O)NCc1cccc(OC(C)C)c1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)CC(C1CC1)C1CC1 +O=C(Nc1cnccc1SCCCO)c1cc2ccccc2[nH]1 +O=C(CSc1ccccc1)NCCOc1ccccc1 +CCOc1ccccc1CNC(=O)Nc1ccccn1 +COc1cccc(CCNC(=O)c2cccc3c2OCO3)c1 +COc1ccc2nc(C(=O)NCc3nc(C)sc3C)ccc2c1 +Fc1ccc2c(cnn2-c2cccc(C(F)(F)F)c2)c1 +Cc1nc(C)n(CC2CN(CC(=O)NC3CCCCCC3)CCO2)n1 +CCCn1cc(C(=O)N(C)CCc2cnn(C)c2)c(C)n1 +COCC(=O)N1CCCC1c1cncc(CN(C)C(C)=O)n1 +Cc1n[nH]c(C2CN(C(=O)Cc3ccn(C(C)C)n3)CCO2)n1 +CSc1ccc(N2C(C)=NS(=O)(=O)c3cccnc32)cc1 +O=C(Nc1cccc(-c2nc(-c3ccncc3)no2)c1)NC1CC1 +O=C(c1cc2ccccc2[nH]1)N(Cc1cccs1)C1CC1 +CCOc1cccc2c1CCNC2C1CCCN1C(C)=O +O=C(Cc1ccc(F)c(Br)c1)c1ccccn1 +CC(C)C(C)NC(=O)Cc1ccc(NC(N)=O)cc1 +CC(C1CC1)N(C)S(=O)(=O)NC1CCc2ccccc2C1 +CCc1cc(C(N)=O)c(NC(=O)c2ccoc2C)s1 +COc1ccccc1CCNC(=O)c1c(C)nn(C)c1C +Cn1cnc(CNC(=O)NCc2cc(Cl)c3c(c2)OCCO3)n1 +COc1ccc(Cl)cc1NC(=O)CSc1ncnc2nc[nH]c12 +CCNC(=O)N(C)Cc1nc(-c2ccc(C)cc2)no1 +COC(=O)N(C)CC(=O)NC1CCN(C(C)=O)CC1 +c1coc(Cn2cnnc2SCc2ncc(-c3cccs3)o2)c1 +CCc1cc(N)cc2c(CC(=O)Nc3cccc(C)n3)noc12 +O=c1c(-c2nc3ccccc3[nH]2)coc2cc(O)ccc12 +NS(=O)(=O)CCNC(=O)C1CNc2ccccc2O1 +Cc1ccccc1OCC(O)Cn1nnc2ccccc21 +CCC(=O)Nc1cccc(NC(=O)NCCC(=O)NC2CCCC2)c1 +CCCC(C)(C)NS(=O)(=O)c1cnn(Cc2ccccc2)c1 +CC(NC(N)=O)C(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +Cc1c(C(=O)NCC2(C(N)=O)CCOCC2)oc2ccc(F)cc12 +Cc1cc(=O)n(CC(=O)N2CCOCC2)c2c(C)cccc12 +CC(=O)N1CCC(c2nccnc2Oc2ccc(F)cc2)CC1 +CC(c1ccccc1)N(C)C(=O)CCNC(=O)c1ccco1 +CC(C)C(C)N(C)C(=O)c1ccc(Cl)cc1N +Cc1ccc(S(=O)(=O)N2CCC3(CC2)OCCCO3)cc1Cl +Cc1nnc(NCc2ccc(Cl)cc2F)s1 +Cn1nc(C(=O)N2CC(c3nc(-c4ccncc4)no3)C2)ccc1=O +O=C(c1cscn1)N1CCC(c2ccccn2)CC1 +CNC(=O)CCc1cc(C)nc(C2CCCN2c2cc(C)ncn2)n1 +N#CCCN(CCC(F)(F)F)Cc1cccc2c1OCCCO2 +COc1cc(Br)c(OC)c2c1C(C)(C)CNC2 +CCN(CC(=O)Nc1ccc2c(c1)OCC(=O)N2)c1ccccc1 +CCCc1nc(C(=O)N2CCC3(CN(C)C(=O)O3)C2)cs1 +CCCn1ncc(-c2ccc(C)cc2)c(C(C)=O)c1=O +Cc1ncccc1NCc1ccc2c(c1)OCCO2 +COC(=O)Nc1cc(OC)c(OC)cc1C(=O)OC +CCC1CCC(CNC(=O)Cn2nc(C)cc2C)CC1 +CC(=O)Nc1ccc(-c2nc3sc4c(c3c(=O)[nH]2)CCC4)cc1 +CCC1CCCCC1NC(=O)NCCNS(C)(=O)=O +COCCNC(=O)c1ccc2c(c1)CCN2C(C)=O +CCCN1C(=O)C(N)c2cc(Br)ccc21 +CCOC(=O)c1cc2nccc(-c3cccs3)n2n1 +Cc1ccc(NC(=O)c2ccc3c(c2)NC(=O)CCS3)c(O)c1 +CCc1nc(NCC(C)O)c2c(n1)c(C)nn2CC +O=C(NCc1ccccc1)N(CC(F)(F)F)C1CCOCC1 +COCCNc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1 +COc1ccc(C(=O)Nc2cccc(C(C)=O)c2)cn1 +Cn1c(=O)c2c(nc(N)n2CC(O)COc2ccccc2)n(C)c1=O +CS(=O)(=O)NCC1CCCCN1C(=O)Cc1ccccc1F +Cc1ccn(CCNC(=O)c2cccc(N3CCCC3=O)c2)n1 +CCn1cnnc1-c1ccccc1NC(=O)COc1ccccc1F +Cc1ccc(NS(=O)(=O)c2cn(C)nc2C)cc1Cl +CCN(CC1CC1)C(=O)Cc1c[nH]c2c(C)cccc12 +CC(C)(C)Oc1cccc(-c2cc(=O)n3ncc(C4CC4)c3[nH]2)c1 +Cc1ccc(-c2csc(NC(=O)c3c(C)noc3C)n2)cc1 +COC(=O)C1CCCN(C(=O)c2cccc(OC)c2)C1 +COC(=O)CSc1nnc(-c2ccccn2)n1N +Cc1cccc(CN(C(=O)c2cc(C)nc3c2c(C)nn3C)C2CC2)c1 +CSc1cc(C(=O)OCCc2c(C)n[nH]c2C)ccn1 +COC1CCCCC1NC(=O)NCC(C)(C)c1ccncc1 +CCOc1ccc(OCC(=O)Nc2ccc3c(c2)C(=O)NCC3)cc1 +Cn1cc(CNC(=O)N2CCc3sccc3C2)cn1 +CCc1cc(NC(=O)NC(C)CC(O)c2ccco2)n(C)n1 +COC(C)C(=O)NC(c1cccs1)C(C)(C)C +CC(C(=O)Nc1ccccn1)n1nc(-c2ccccc2)ccc1=O +CC(NC(=O)c1cc(S(C)(=O)=O)ccc1Cl)C1CCCO1 +Cc1ccc(NC(=O)C2CC2)cc1NC(=O)c1ccc2c(c1)COC2 +CCC(=O)N1CCN(C(=O)c2cc(OC)cc(OC)c2)CC1 +Cc1ccoc1C(=O)Nc1nc2c(s1)CN(C)CC2 +Cc1cc(O)c(C(C)C)cc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +CC(=O)N1CCc2cc(NS(=O)(=O)c3cccc(F)c3)ccc21 +Cn1cc(C2CCCN2C(=O)c2cccc(Cn3ccnc3)c2)cn1 +Cn1c(SCc2cc(=O)n3ccsc3n2)nnc1-c1ccco1 +Cc1ccc(CNC(=O)CCc2c(C)nn3cnnc3c2C)o1 +Nc1cccc2c1CN(c1cc(Br)ccc1F)C2 +COc1ccc(N2Cc3ccccc3OC(C)C2=O)cc1 +O=C(CSc1nnc(-c2ccc(O)cc2)o1)Nc1nccs1 +CCc1nc(CN2CCN(C(=O)c3ccc(O)cc3)CC2)cs1 +O=C(CC(F)(F)F)N1CCN(S(=O)(=O)c2cccnc2)CC1 +CCN(C(=O)c1ccc(C)[nH]c1=O)C(C)COC +Nc1cc2c(cc1Oc1cccnc1)NC(=O)CC2 +CC(C)S(=O)(=O)c1nsc(C(=O)N2CCCC2)c1N +Cc1ccc2c(c1)N(Cc1nc(-c3cccnc3)no1)C(=O)CO2 +CCc1ccccc1NC(=O)N1CCN(c2cc(C)ncn2)CC1 +CC(C)C(NC(=O)c1ccc2[nH]ccc2n1)C(=O)Nc1nccs1 +CCC(C)C(NC(N)=O)C(=O)NCc1sccc1C +CSc1nnc(SCC(=O)Nc2ccc(Cl)cn2)s1 +CCc1csc(C2CCCN(C(=O)c3cccc(OC)c3F)C2)n1 +COc1ccc2[nH]c(=O)c(CNc3cc(C)cc(C)c3)cc2c1 +COCc1ccccc1NC(=O)NCCc1cn2ccccc2n1 +CS(=O)(=O)N1CCC(NC(=O)c2cn3ccccc3n2)CC1 +CCOC(CC)C(=O)Nc1ccc(SCC)nc1 +Cc1cccc(N2CCN(C(=O)c3cccnc3)CC2)c1C +CCc1nc2onc(C)c2c(=O)n1CC(=O)N1CCOCC1 +O=C(CCOc1ccc(Cl)cc1)Nc1cnn(CC2CCCO2)c1 +COCC(=O)OCC(=O)Nc1ccc(C(C)=O)cc1 +CC1c2ncc(Cn3cncn3)n2CCN1S(=O)(=O)C1CC1 +O=C(NCC1CCCCC1)C1CCN(c2ccc3nncn3n2)CC1 +C#CCN(CC=C)Cc1nc(-c2ccc(F)cc2F)oc1C +CCNC(=O)NC1(C(=O)Nc2cc(F)c(OC)c(F)c2)CCCC1 +Cc1cc(Cl)ccc1OC(C)C(=O)OCC(=O)C1=NC=CC1 +O=C1Nc2ccccc2C12CCN(c1nccs1)CC2 +Cc1cc(Br)ccc1NC(=O)c1ccc(NC(N)=O)cc1 +CS(=O)(=O)c1cccc(OCc2nc(-c3cccs3)no2)c1 +COc1ccc(C(=O)N2CCCC(c3nc(CC(C)C)no3)C2)cc1 +O=C(C1COc2ccccc2O1)N(Cc1ccccc1F)C1CC1 +NC(=O)c1ccc(NC(=O)COc2cc(Cl)ccc2Cl)cc1 +CNC(=O)c1ccc(CSc2nnc(C3CC3)n2C)cc1 +O=C(OCc1nc2ccccc2c(=O)[nH]1)c1cc2c(s1)CCC2 +Cc1noc(NC(=O)c2ccc(OC3CCCC3)cc2)n1 +CCOc1ccc(S(=O)(=O)NCc2cccnc2OC)cc1 +COc1cc(CC(=O)Nc2cccc3cccnc23)ccc1C +COc1ccc(NC2COc3cc(O)ccc32)cn1 +NC(=O)c1cccc(CNC(=O)c2ccc3c(c2)Cc2ccccc2-3)c1 +Cc1ccc(OCCc2nc(C(C)N)cc(=O)[nH]2)c(C)c1 +Cn1ccnc1SCC(=O)NCC#Cc1ccccc1 +CC(NC(=O)c1cc2c(s1)-c1ccccc1OC2)c1ccccn1 +COCC(O)c1cc(Cl)cc2c1NC(=O)C2C +COc1cccc(-c2nnn(CC(=O)N3CCCC(C)C3)n2)c1 +COC(=O)c1c(NS(C)(=O)=O)c2cc(C)ccc2n1C +Cn1c2c(ccc1=O)CC(NC(=O)Cc1ccsc1)CC2 +Cc1nn(-c2ccccc2)cc1CCCNC(=O)NCc1ccccn1 +N#CC(NC(=O)c1csc(-c2ccc(F)cc2)n1)C(N)=O +CCCS(=O)(=O)NCc1cccc(C(=O)N(C)C)c1 +CN(C)C(=O)c1ccc(NCC(=O)Nc2ccc(F)c(Cl)c2)cc1 +O=C(Nc1ccc(Cl)cc1)N1CCN(C(=O)C2CC=CCC2)CC1 +Cc1cccc2cc(C#N)c(N3CCC(=O)CC3)nc12 +CN1CC(C(=O)NCC(=O)OCc2ccccc2)CC1=O +c1cnc(N2CC3COCC3(COCc3cccnc3)C2)nc1 +O=C(C1CC=CCC1)N1CCN(C(=O)C2CC=CCC2)CC1 +COc1ccc(C(=O)CNC(=O)Cc2ccccc2)c(OC)c1 +O=C(NCCNS(=O)(=O)c1cn[nH]c1)C1CC1 +CC(Sc1ccc(C(C)C)cc1)C(=O)N(C)CCC#N +Cc1ccc(N(CCCN)Cc2cccs2)c(C)c1 +Cc1c(CN2CC(C)(c3ccccc3)CCC2=O)cnn1C +O=C(c1ccc(F)nc1)N(Cc1ccccn1)c1ccc(F)cc1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2cccc(Cl)c2N(C)C)c1C +O=c1[nH]c2ccc(S(=O)(=O)N3CCCC3)cc2[nH]c1=O +CCCCNC(=O)c1nccc2c(N)c(OC)c(OC)cc12 +COc1cc(CCC(=O)N2CCC(C)CC2)cc(N)c1OC +COC1C2CCC1N(Cc1sccc1C)CCO2 +COCCN(Cc1ccccc1)C(=O)Cc1ccc(C)nc1 +CC(NS(=O)(=O)c1cc(F)ccc1F)c1ccc2c(c1)OCO2 +Cc1ccc(-c2nnc(SCC(=O)Nc3nc(C)no3)n2C)cc1 +Cn1c(=O)n(CC(=O)NCc2ccc(F)cc2)c2cncnc21 +CC1CCCCC1NC(=O)COc1ccc(F)cc1 +CNC(=O)C1CCC(NS(=O)(=O)c2ccc(C)s2)CC1 +CCOc1ccccc1OCC(=O)NCC1CCCO1 +O=C(C1CSc2nccc(=O)n2C1)N(CCO)c1ccccc1 +CCn1nc(-c2nc(-c3cc4ccccc4o3)no2)ccc1=O +Cc1nnc(SCc2ccc(Br)cc2F)n1C +c1ccc(CCn2c3ccccc3c3nn4nnnc4nc32)cc1 +Cc1cccc(C)c1NC(=O)c1cccc(NC(=O)C(C)C)c1 +CCNC(=O)c1cccc(NC(=O)c2ccc(C)o2)c1 +CC(C)(C)OC(=O)N1CCCC1CSc1cc(C#N)ccn1 +CCN1CCN(C(=O)c2cnc3[nH]nc(C)c3c2)CC1 +Cc1nc(C2CCCN(C(=O)c3cscn3)C2)c2cccnc2n1 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)N1CCC1 +Cc1nc2ccccc2n(CCC(=O)Nc2ccccc2Cl)c1=O +COc1cc(C)c(C(=O)Nc2ccccc2-n2cnnn2)cc1OC +COc1cccc(C2CCCN2S(=O)(=O)c2ccc(F)cc2)c1 +CN(C)C(=O)N1CCC2C1CCC(=O)N2c1ccccc1 +NC(=O)CCn1c(SC2CCCCNC2=O)nnc1-c1ccco1 +CCC(CC)C(=O)N1CCC(Oc2cccnn2)CC1 +CCC(C)n1nccc1NC(=O)Cn1ccccc1=O +CCC(C)NC(=O)C1(c2cc(-c3ccc4c(c3)OCO4)on2)CC1 +CC(C)(C(=O)N1CCC(CS(N)(=O)=O)CC1)c1ccccc1F +Cc1ccccc1NC(=O)c1cc(S(N)(=O)=O)cs1 +COc1ccc(OC)c(C(C)NS(=O)(=O)C(C)C)c1 +CCn1ccc(NC(=O)c2cc(NC(C)=O)n(-c3ccccc3)n2)n1 +Cc1cc(C(=O)Nc2ccc3c(c2)OCCO3)on1 +CC(NC(=O)C1CC(=O)N(C(C)C)C1)c1nnc2n1CCCCC2 +O=C(c1ccoc1)N1CCC2OC(COCC3CCOCC3)CCC21 +CCc1cccc2c(=O)c(C(=O)N3CCN(C)CC3)c[nH]c12 +Cc1cccc(CN2CCCC3(CCN(C(=O)C(C)(C)C)C3)C2=O)c1 +COc1ccccc1S(=O)(=O)CC(=O)Nc1c(C)cccc1C +CC(C)c1cc(C(=O)OC2C3CCOC3C2(C)C)n[nH]1 +COC(=O)c1ccc(NC(=O)Cn2cc(Br)cn2)cc1 +CCOc1ccc(-n2nnc(CO)c2C(C)(C)C)cc1 +O=C(CSc1ccc(F)cc1)Nc1ccc2cn[nH]c2c1 +O=C(Cc1ccccc1F)Cn1cc(Cl)cn1 +O=C(c1cc(Cl)ccc1-n1cnnn1)N1CCc2ccccc21 +Cc1ccc(NS(=O)(=O)c2ccc3[nH]c(=O)oc3c2)c(C)c1 +O=C(NCC1Cn2nnc(-c3ccncc3)c2CO1)c1cccs1 +COc1ccccc1OCc1nc(C2CC2)c(C#N)s1 +COc1ccc(CNC(=O)c2cc(C3CC3)nn2-c2ccccc2)cc1 +CN(C)C(=O)C(O)c1ccc(-c2ccccc2)cc1 +CCCC1CN(C(=O)c2cncc(OC(C)C)c2)CCO1 +OCc1cn(Cc2noc(-c3cccs3)n2)nn1 +CCn1nc(C)c(CNC(=O)c2ccc(OC(C)C)cc2)c1C +Cc1cc(C(=O)NC2CCN(C(=O)c3ccoc3C)CC2)on1 +CC(=O)c1cccc(NC(=O)N2CCNC(=O)C2C)c1 +c1ccc2c(c1)NCCN2CCOc1ccc2ncccc2c1 +Cc1nn(S(=O)(=O)N2CCC(C)CC2)c(C)c1Cl +COC(=O)N1CCCC(c2nc(-c3cc4ccccc4o3)no2)C1 +O=c1c2c(-c3ccccc3)n3ncnc3nc2ccn1-c1ccccc1 +COC(=O)c1cnn2c1NC(c1ccccc1)CC2C(F)(F)F +COC(=O)C1CCN(C(=O)c2c(C)noc2C)CC1 +CN(C(=O)c1cncc(Br)c1)c1ccc(F)cc1 +COc1cc(N2CCc3onc(COCC(=O)N(C)C)c3C2)ncn1 +Cc1ccc(CC(=O)N2CCCCC2c2nc[nH]n2)cc1 +CC(C)(C)OC(=O)N1CCCC2CC(=O)CCC2C1 +Cn1nnnc1SCCC(=O)NC1CCCNC1=O +CNS(=O)(=O)c1ccc(C(=O)NCC(C)Oc2ccccc2)o1 +O=C(c1ccccn1)N1CCC(n2c(=O)[nH]c3cncnc32)C1 +Cc1nnc(SCCOc2cccc(F)c2)n1CC(N)=O +CC(=O)NC(C)C(=O)Nc1ccc(Sc2nccn2C)cc1 +O=C(C1CCCCC1)N1CC(c2nc(-c3ccncc3)no2)C1 +CCC(=O)NCC(=O)Nc1cccc(N2CCCCCC2)c1 +O=C(Nc1ccccc1C(=O)N1CCCCC1)C1CCCC1 +CC(=O)Nc1cccc(C(=O)N(C)Cc2cccc(F)c2)c1 +O=C(Nc1ccccc1)N1CCCC(c2nnc3n2CCCCC3)C1 +Cc1cc(N)ccc1NC(=O)c1cccc(Cl)c1 +CCn1nccc1C(=O)N1CCCc2ccccc21 +CS(=O)(=O)N1CCOCC2(CCN(C(=O)c3ccc[nH]3)CC2)C1 +CCC(CC)c1nnc(NC(=O)Cc2c[nH]c3ccccc23)s1 +CN1CCN(C(=O)c2nccc3cc(N)ccc23)CC1 +COc1ccccc1CNC(=O)CCn1ncc2ccccc21 +CC1CCCN(C(=O)Cn2nnc(-c3ccccc3F)n2)C1 +CCc1cc(C(=O)N2CCOCC2)nc2cc(-c3cccs3)nn12 +Cc1cc(CN(C)C(=O)Cc2c(C)nc3ccccc3c2C)no1 +Cn1nnnc1SCc1ccc(Cl)cc1Br +COCCCNC(=O)Cn1ncc2ccc(Cl)cc21 +Cc1ccn(-c2ccc(N3CCN(C(=O)C(C)C)CC3)nn2)n1 +O=C(Nc1nc(-c2ccc[nH]2)cs1)c1cnn(-c2ccccc2)c1 +Cc1nc(NC(=O)c2ncn(-c3ccccc3)n2)cc(C2CC2)n1 +Cc1cccc(Cl)c1NCC(=O)N(C)CC(=O)NC1CC1 +CC(=O)c1ccc(N2CCN(Cc3ccccc3F)CC2)cc1 +CS(=O)(=O)c1ccc(NC(=O)NCc2cccc3c2OCO3)cn1 +CN(C)C(=O)CN(C)C(=O)c1cc2cc(Cl)ccc2o1 +Nc1ccc2c(c1)N(C(=O)COc1ccc(F)cc1)CCC2 +O=C(NCC#Cc1ccccc1)c1sccc1C1CC1 +CN(Cc1cccc(C#N)c1)C(=O)c1cccnc1SC(F)F +Cc1nc(-c2ccc(NC(=O)NCc3cnn(C)c3)cc2)cs1 +Cc1cc(CNCCc2nccs2)cc(C)c1O +Cc1n[nH]c(C)c1CCOC(=O)CC1=CCCCC1 +Cc1ccc(N2CCC(c3ccc4ccccc4c3)C(O)C2)nn1 +Cc1nn(CC(C)C)c(C)c1CCC(=O)NCC(N)=O +Cc1nn(C)c2nc(NCc3cc(F)c(F)c(F)c3F)sc12 +O=C(CCN1CC(=O)N2CCCCC2C1=O)NCc1ccc(F)cc1 +Cc1ncc(C(C)NCC(O)COc2ccc3c(c2)OCO3)s1 +Cc1csc(NC(=O)CN2CCCCCC2=O)n1 +CCNC(=O)N1CCN(C(=O)c2cccc(C)c2C)CC1 +Cc1cc(Cl)cc(Br)c1OCCn1ccnc1 +O=C(NCC1(c2ccc(F)cc2)CCOCC1)c1ccc(F)nc1 +Cc1nc(-c2cccc(S(=O)(=O)N3CCC(C)CC3)c2)cs1 +NC(=O)CCC(=O)N1CCC(c2ccc3c(c2)OCO3)C(O)C1 +Cc1cccc2cnn(CCC(=O)N3CC(C)OC(C)C3)c12 +CCC1CCCC(NC(=O)NCCNC(=O)OC(C)(C)C)C1 +CC(NC(=O)Cc1ccccc1)c1ccc2c(c1)OCO2 +CC(C)(C(=O)N1CCc2cnccc21)c1ccc(F)cc1 +COc1ccccc1-c1nnc(SCC(=O)C(C)(C)C)n1C +Cc1n[nH]c(C(=O)Nc2ccccc2OC(C)C)c1Br +CC(C)S(=O)(=O)N1CCCC(c2ccccn2)C1 +Nc1ccc(F)c(NC(=O)CCCn2cccn2)c1 +Cc1ccccc1-n1nnc(-c2cccnc2)c1N +O=C(NCc1ccccc1-n1cccn1)c1c(F)cccc1F +c1ccc(CSc2ncc(-c3ncc[nH]3)cn2)cc1 +Cc1ccc(C)c(-c2ncnc(N(C)C)c2NC(=O)C2CC2)c1 +CC(=O)Nc1ccc(NC(=O)CSc2nnc(C)s2)cc1C +COc1ncc(CNc2ccc(F)cn2)c(OC)n1 +COC(=O)Cn1c(=NC(=O)C(C)C)sc2cc(NC(C)=O)ccc21 +CC(C)CC(C)NS(=O)(=O)c1ccc(O)cc1 +Cc1ccccc1-n1nc(C(=O)N2CCNC(=O)CC2)c2c1CCC2 +CCN(C(=O)C12CCC(C)(C(=O)O1)C2(C)C)c1cccc(C)c1 +CC(C)C1CCC(C(=O)NCC(O)c2cccnc2)CC1 +Cc1c(N)cc(S(=O)(=O)Nc2cn[nH]c2)cc1Cl +CC(Cc1cccs1)NC(=O)C(C)Oc1ccc(C#N)cc1 +Cc1cc(C)cc(OCC(O)CN2CCN(C(=O)N(C)C)CC2)c1 +Cc1ccc(N2Cc3nc(=O)n(Cc4ccccc4F)n3C2=O)cc1 +Cc1ocnc1CNS(=O)(=O)c1ccc(Cl)c2ncccc12 +CC1CC(Oc2ccc(S(C)(=O)=O)cc2)C(=O)O1 +Cc1ccc2ncc(CN3CCOC(c4ccc(F)c(F)c4)C3)n2c1 +CN1CCN(c2cc(-c3ccccc3)nc3ncnn23)C(C)(C)C1=O +O=C(c1c[nH]c2ccccc12)N1CCOC(c2ccc(F)cc2)C1 +N#Cc1cccc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)c1 +CC1CCN(C(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)CC1 +CCC(=O)Nc1cccc(NC(=O)NC(C)CCCO)c1 +CCNC(=O)c1ccc(NC(=O)NCCN(C)c2ccccc2)cc1 +CCCCN(C(=O)Cn1c(=O)cnc2ccccc21)C(C)CC +CC1CCCN(C(=O)c2cc(Br)ccc2F)C1 +CCC(C(=O)N1CCN(c2ccc(C)cc2)C(=O)C1)n1cccn1 +CCC(C)C(NC(=O)COc1cc(Cl)ccc1Cl)C(N)=O +COc1cc(-n2cnnn2)ccc1NC(=O)c1cnc2ccccc2n1 +O=C1CCCN1CCCOc1cccc(Cl)c1Cl +Cc1nc(NC(=O)c2cc(Br)cn2C(C)C)sc1C +CSc1ncc(CNc2nc(C)nc3oc(C)nc23)n1C +Cc1cc(C)c2oc3c(c(=O)c2c1)C(c1ccccc1)NC3=O +Cc1cc(N)nc(SCc2cc(C#N)ccc2F)n1 +COc1ccc(CNC(=O)C2(C)CCN(S(C)(=O)=O)CC2)cc1 +COC(=O)CNC(=O)c1nccc2cc(N)ccc12 +CCOC1CCN(C(=O)Nc2ccc(F)c(-n3nnnc3C)c2)CC1 +Cc1nc(C)c(CNC(=O)NCCc2ccc3c(c2)CCO3)s1 +CC(Nc1nnc(C(C)(C)C)s1)C1CCCO1 +COCCCNC(=O)N1CCN(Cc2cccs2)CC1 +O=C(COC(=O)c1ccc(F)cc1)NC1CCCc2ccccc21 +COc1cc(CO)ccc1OCC(=O)NC1CC1 +COc1ccc(C(C)NC(=O)CCNc2cnc3cnccn23)cc1 +O=C(CCCNC(=O)c1ccco1)Nc1ccc2c(c1)OCO2 +Cc1nnc(NC(=O)CSc2nnc(Cc3ccccc3)o2)s1 +Cc1ccc(F)c(NC(=O)NCCNC(=O)c2ccc(Cl)cc2)c1 +CC(C)CCn1cc(-c2cccc(F)c2C(N)=O)cn1 +COc1ccc(C)cc1NC(=O)N1CCNC(=O)C1 +CC(=O)Nc1nc(-c2nc3ccccc3s2)cs1 +COc1ccccc1OCC(=O)N(C)Cc1ccccc1 +COc1cc(CNC(=O)Cc2cccc(F)c2)ccn1 +COCCNS(=O)(=O)c1ccc(Cl)c2ccccc12 +Nc1ccc2oc(CC(=O)NCC3CCCO3)nc2c1 +CN(C(=O)c1ccc2[nH]cnc2c1)c1ccc2ccccc2n1 +O=C(Nc1cccc2ccccc12)N1CC=CCC1 +CC1CN(C2CCN(CC3CCCO3)CC2)CCO1 +COC(=O)N1CCC(NC(=O)c2ccccc2-c2ccccc2)CC1 +O=C(Nc1ccc(F)c(F)c1)C1CN(S(=O)(=O)C2CC2)C1 +COc1ccccc1Cn1c(C2CC(=O)N(C)C2)nc2ccccc21 +Cc1cc(NC(=O)NC(C)C2CCOCC2)c2ncccc2c1 +COCCCn1ccc(NC(=O)c2ccc(F)c(Cl)c2F)n1 +CCCCN1CCN(C(=O)c2cn3cccc(C)c3n2)CC1 +N#Cc1cccnc1Nc1ccc2c(c1)OCCO2 +O=C(NC1CC1)c1nnc(Cc2ccc(F)cc2)o1 +CCc1ccc(C(=O)N(CC(=O)OC)C(C)C)cc1 +CNC(=O)c1ccc(OC2CC2)c(Br)c1 +Cc1cc(C(=O)N2CCC(C(N)=O)c3ccccc32)sc1C +Nc1ccccc1N1CCN(C(=O)NC2CCCCC2)CC1 +N#Cc1ccc(Cn2c(=O)[nH]c3ccc(F)cc32)cc1 +COc1c(C)cc(S(=O)(=O)NCC2CCCO2)c(C)c1C +O=c1ccc(-c2nc(-c3ccncc3)no2)nn1Cc1ccccc1 +Cc1ccc(-c2nc(-c3ccccn3)cc(=O)[nH]2)cc1 +NC(=O)C1CCN(C(=O)C2CCCc3ccccc32)CC1 +CCOC(=O)c1nn(-c2ccccc2Br)c(N)c1C +CCCNC(=O)CNc1c(C)cc(Br)cc1C +CC(C)CC(=O)c1ccc(S(=O)(=O)CC(O)CO)cc1 +CCOc1ccc(NC(=O)CCc2nc(-c3ccsc3)no2)cc1 +Nc1nc(-c2cc(F)c3c(c2)CCC(=O)N3)cs1 +CCc1ccccc1NC(=O)CSc1ccc(NC(C)=O)cc1 +C=CCNC(=O)c1c(F)c(F)c(F)c(F)c1F +CC(C)Oc1ccccc1CNc1cnn(-c2ncccn2)c1 +c1ccc(-c2nc(CSc3ncn[nH]3)no2)cc1 +CCOc1cc2c(cc1OCC)C(=O)C(C#N)C=N2 +O=C(NCc1cscn1)C1CCCN1C(=O)c1ccco1 +CC(=O)NCc1ccc(C(=O)N(CCC#N)CCC#N)cc1 +CC(C)Sc1ccccc1C(=O)OCC1CCC(=O)N1 +Cc1c(NC(=O)Cc2ccccc2F)c(=O)n(-c2ccccc2)n1C +COCCCNC(=O)COc1ccc(Cl)cc1C +CSc1ccc(CN(C)c2cc(C)nc3ncnn23)cc1 +CCCCOc1ccc(OC)cc1NC(=O)C1CCN(C(C)=O)CC1 +Nc1ccc(Cl)c(C(=O)N2CCCCCC2)n1 +COc1ncc(NC(=O)CCc2ccccc2)cn1 +CC(NC(=O)COn1nnc2ccc(Cl)cc21)c1ccco1 +CC(C)(CNC(=O)C1(c2ccc(F)cc2)CCC1)c1ccncc1 +Nc1cncc(-c2ccccc2OC(F)(F)F)c1 +O=C(Cc1ccccc1F)N1CCn2c(cccc2=O)C1 +Cc1cc(NC(=O)c2ccc(-c3ccccc3F)o2)ccn1 +COc1ccc(Br)c(C(=O)NC2CC(O)C(CO)C2)c1 +CCC1=C(C(=O)OC)C(c2ccc(O)cc2)NC(=O)N1CC +Cc1ccc(CNC(=O)N2CCCN(S(C)(=O)=O)CC2)cc1 +CN(Cc1ccco1)C(=O)Nc1nnc(Cc2ccccc2)s1 +COc1ccccc1CC1CCCN1C(=O)CCc1cnn(C)c1 +COc1ccc(N2CCN(CC(=O)Nc3cccnc3)C2=O)cc1 +Cc1nnc(SCC=CCSc2nnc(C)n2N)n1N +CCOc1ccccc1NC(=O)c1cccc(N(C)C)c1 +Cc1cc(NCc2cccc(C#N)c2)ccc1C(N)=O +CCCOc1cccc(C(=O)N2Cc3ccccc3CC2C(N)=O)c1 +CN(C)C(=O)c1cc(NC(=O)NC(CO)c2ccccc2)ccn1 +C#CCNC(=O)C(C)N1Cc2c(OC)ccc(OC)c2C(O)C1 +O=C(OCC1CC(=O)N(C2CC2)C1)C1CC1c1cc(F)ccc1F +O=C(Cn1c(=O)oc2ccccc21)Nc1ccc(O)c2ccccc12 +COc1ccc(C)cc1S(=O)(=O)Oc1ccc2c(c1)ncn2C +Cc1ccc(O)c(C(=O)c2cnn(-c3oc(C)nc3C#N)c2)c1 +C=CCOc1cccc(NC(=O)CN(C)C(=O)c2ccccc2)c1 +CCCCc1cc(NC(=O)c2cnn(-c3ccccc3F)c2C)[nH]n1 +O=C(CCc1ccsc1)Oc1ccc(NC(=O)c2ccco2)cc1 +Cc1c(C(=O)c2ccc(F)cc2)cnc2ncnn12 +O=C(CSc1ccccc1)N1CCC(C(=O)N2CCOCC2)CC1 +O=C(NCCNC(=O)c1cc2cccnn2n1)c1cccc(Cl)c1 +CC(C)c1ccc(C2CC2C(=O)N(CCC#N)CCC#N)cc1 +CN(C)S(=O)(=O)c1ccc(CN2CCOc3ccc(F)cc32)o1 +CCCC1CN(C(=O)CSc2ccc(F)cc2)CCO1 +CCOCC(=O)NC1CCN(c2ncc3c(n2)CCOC3)CC1 +CCCNC(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C +COc1cccc(OCCCC(=O)n2ccnc2)c1 +Cc1ccc2c(cnn2CCC(=O)NCc2ccc(C)o2)c1 +CC1CCN(C(=O)c2ccc3c(c2)CCCN3S(C)(=O)=O)CC1 +CCc1nc(N2CCCC2)c2cnn(-c3ccccc3Cl)c2n1 +O=C(Nc1cccc2cnccc12)N1CCCC1c1ccsc1 +O=S(=O)(Cc1cccc(Cl)c1)NCc1ccco1 +O=C(COC1CCCCC1)Nc1ccc(N2CCCCC2)cn1 +CCN1CCN(CCOc2ccccc2C)C(=O)C1=O +CCCNc1ccccc1S(=O)(=O)NCC(C)(C)C +CNC(=O)CCc1cc(C)nc(C2CCCN2c2cnccn2)n1 +Cc1ccc(F)cc1NC(=O)c1cnn(-c2ccc(F)cc2)n1 +COc1cccc(C(=O)N(Cc2cccn2C)C2CC2)c1OC +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)C(C)(C)c1ccccc1 +CSc1ccc(CNC(=O)c2ccccc2F)cc1 +C#CCn1cc(CN(C)C(=O)c2c(C)cc(C)cc2C)cn1 +O=C(NCc1ccccn1)c1ccc(Cn2cccn2)cc1 +CCOc1cc(N)cnc1N(C)Cc1ccccc1 +O=C1CC2C(CCN2C(=O)c2cccs2)N1Cc1ccncc1 +CC(=O)Nc1ccc(S(=O)(=O)Oc2ccccc2)cc1 +O=C1CN(C(=O)CCS(=O)(=O)c2ccc3c(c2)CCC3)CCN1 +CC(=O)OCC(CO)CCn1cnc2cnc(N)nc21 +COc1cc(S(=O)(=O)n2ccnc2)c(C)cc1Br +CC(=O)Nc1c(C#N)sc(C)c1-c1cccc(C)c1 +CCn1c(=O)c2c(nc3n(CC4CCCO4)c(C)cn23)n(C)c1=O +CC(C)C(Sc1nnnn1-c1ccccc1)C(=O)NC1CCCC1 +COc1ccc(C(NC(=O)c2cc(C)cc(C)c2)c2nccn2C)cc1 +O=C(Cc1cccnc1)N1CCCC(CCc2ccc(F)cc2)C1 +CC(=O)Nc1ccc(C(O)CN(C)c2ccccc2)cc1 +CC(C)(C)n1ncc2c1CCCC2NC(=O)C1CCC1 +CCCN1C(=O)CCc2cc(NC(=O)CCC3CCCO3)ccc21 +COc1ncc(CN(C)Cc2cc3cc(F)ccc3[nH]2)cn1 +Nc1ccc(C2=CCCc3nonc32)c2nonc12 +CC1CCCCC1NC(=O)c1noc2c1CCCC2 +Nc1ccc(-n2ccc(C(F)(F)F)n2)c(Cl)c1 +CCNC(=O)CN(CC)C(=O)c1ccc(-c2cnco2)cc1 +CC(C)(C)OC(=O)n1cc(C(C)(C)C#N)c2cc(F)ccc21 +Cc1cc(S(=O)(=O)N2CCC(C)CC2)ccc1Cl +NC(=O)C1CCC(CNC(=O)c2cccc(-c3ccoc3)c2)O1 +Fc1ccc2[nH]c3c(NCCc4ccccc4F)ncnc3c2c1 +COc1ccc(C(C#N)NS(C)(=O)=O)c(OC)c1 +Cc1ccc(NCCC(O)c2cccc(N)c2)c(C)c1 +Cc1ccc(-c2nnc(SCC(=O)NCC3CCCO3)n2C)cc1 +O=C(NCc1ccncn1)C1COc2ccccc2C1 +Cc1nnc(SCC(=O)NC(C)c2cccs2)s1 +COc1c(Cl)cccc1NC(=O)COc1ccc(C(N)=O)cc1 +Cc1nnc(SCC(=O)Nc2nnc(-c3ccccc3)s2)s1 +COc1cc(C#N)ccc1OC(C)C(=O)Nc1c(C)cc(C)cc1C +O=C(CCn1cccn1)N1CCc2sccc2C1 +CN(CC(F)F)C(=O)c1cccc(OCC(F)F)n1 +CC(NS(=O)(=O)c1ccccc1S(C)(=O)=O)c1cccs1 +CC(C(=O)Nc1cccc(C#Cc2ccccn2)c1)c1ccsc1 +CC(C)(C)CC(=O)Nc1nnc(C2CCCCC2)s1 +O=C(Nc1ccncc1)N1CCCC1C1CCCCC1 +CCc1ccc(N2CC(C(=O)NC3CCC(O)CC3)CC2=O)cc1 +Cc1cccc(OCC(=O)NCc2cc(-c3ccncc3)n(C)n2)c1 +CCNC(=O)C(C)NC(=O)CNc1ccccc1Cl +CC(=O)NCC(=O)NCCOc1cccc(Cl)c1 +Cc1cccc(-c2c(-c3ccccc3)ncn2CCc2ccccn2)n1 +CC(C)CCC(C)NC(=O)NCC(=O)NC1CC1 +C=CCNS(=O)(=O)c1cccc(C(=O)NCC(C)O)c1 +CC(C)Cc1nnc(NC(=O)NC(C)c2ccc(F)c(F)c2)s1 +CC(CC#N)N(C)C(=O)c1cccc(OCc2cccnc2)c1 +O=C(CC1C=CCC1)NCc1nnc2ccccn12 +CCC(=O)c1cn(CC(=O)NCc2ccccc2)c2ccccc12 +CCOc1ccc(S(=O)(=O)NCC(=O)NC2CCCCC2)cc1 +CCc1nnc(NC(=O)c2cccc(N3CCCC3=O)c2)s1 +CCOCC(=O)N(C)C1(C(=O)OC)CCCCC1 +Cc1cccc(C(=O)NC(C(=O)N(C)C(C)C)C(C)C)c1 +CC(C(N)=O)n1ccnc1-c1ccc(F)cc1F +COc1ccc(Br)c(CN(C)Cc2nc(C)cs2)c1 +COc1ccc(N)cc1-n1cc(-c2ccc3c(c2)OCO3)nn1 +Cc1cc(S(=O)(=O)NCc2cnn(-c3ccccc3)c2)c(C)o1 +Fc1ccc(-c2nc(Cn3ccnc3-c3cnccn3)cs2)cc1 +Nc1nc2cc(F)c(F)cc2n1Cc1ccccc1F +COC(=O)c1ccccc1NC(=O)c1cc(C)sc1C +Cc1csc(=O)n1CCC(=O)NCC1CCCCC1 +COCCN1CCN(C(=O)CCc2nc(C)no2)CC1=O +Cc1nc2[nH]nc(NC(=O)c3ccccc3)c2c(C)c1Cl +CCS(=O)(=O)N1CCCC(C(=O)NCc2ccccn2)C1 +Cc1nccc(N2CCCC(c3cncc(-n4ccnc4)n3)C2)n1 +N#Cc1cnc(NCCNc2ncc(C#N)c(N)n2)nc1N +CC(=O)c1cc(C)ccc1OCC(=O)NCC1CC1 +O=S1(=O)c2ccccc2S(=O)(=O)N1Cc1ccccc1Cl +CS(=O)(=O)N1CC(C(=O)Nc2ccccn2)Oc2ccccc21 +O=C(c1cnn2ccccc12)N1CCCc2ccccc21 +O=C(Cn1c(=O)[nH]c2ccccc21)NCCCn1cnc2ccccc21 +CC(C)(C)OC(=O)N1CCCC(c2nccs2)C1 +O=C(NC1CN(c2nncs2)CC2CCCOC21)c1ccncc1 +CC(C)(C)OC(=O)NCc1cccc(CCO)c1 +CCC(=O)Nc1cccc(C(=O)NCc2sc(C)nc2CC)c1 +CC1CC(Nc2ccc(Oc3ccccc3)cc2)C(=O)O1 +OC1(C#Cc2ccccn2)C2CC3CC(C2)CC1C3 +N#Cc1cccc(C(=O)OCc2nnc(-c3ccccc3)o2)c1 +CC(C)COc1nc(NC(C)C(N)=O)ccc1N +COc1cccc(OC)c1COC(=O)c1cccn1C +Cc1ccc(-c2nc3c(N)cccc3n2CC(N)=O)cc1 +COCCCn1c(=O)c2sccc2n(Cc2ccccc2)c1=O +CCC(CC)C(=O)Nc1ncc2c(n1)CC(C)(C)CC2=O +Cc1ccc(CN2CCNC(=O)C2(C)C)c(Br)c1 +Cc1cccnc1CNC(=O)NCCCCC(C)C +CCn1nc(CCOC)nc1C(C)Oc1ccc(F)cc1F +O=C1CN(C(=O)c2cc3cc(Cl)ccc3o2)CCN1 +COc1ccc2c(c1)OCC(Cc1cnc(N)nc1)C2 +Cc1nnc(CNC(C)c2ccc(-n3cccn3)cc2)s1 +Nc1ccc(C(=O)OCCC(=O)NC2CC2)c(F)c1 +COCc1nc2sc(-c3ccccc3)cc2c(=O)[nH]1 +Cc1nc2scc(-c3ccc(Cl)cc3)n2c1N +CC(=O)Nc1ccc(CC(=O)Nc2nc3ccccc3s2)cc1 +O=C1Cn2nc(C=Cc3c[nH]c4ccccc34)nc2-c2ccccc2N1 +CCn1c(C)cc(C(=O)Nc2ccc(OC)cc2)c1C +COc1ccc(CCN2CC(NC(=O)c3ccc[nH]3)CC2=O)cc1 +COc1ccc(CN(C)C(=O)CN(C)CCC#N)cc1F +CC(OCCCNC(=O)C1CC=CC1)c1ccccc1 +CCC(C)c1ccc(NS(=O)(=O)c2c(C)noc2C)cc1 +O=C(NCC1CCCO1)C1CC(=O)N(C2CC2)C1 +Cn1cc(NC(=O)CC2(CC(=O)Nc3cnn(C)c3)CCCC2)cn1 +Cc1cccnc1NC(=O)CNC(=O)c1cccc(F)c1 +CC(C)C(=O)c1ccccc1NC(=O)c1cccc(-n2ccnn2)c1 +CCN(CCOC)c1ccc(-c2nc(C)no2)cn1 +O=C(Nc1nccs1)c1csc(Nc2ccccn2)n1 +CC(OCc1ccccc1)C(=O)NCc1cccc(S(N)(=O)=O)c1 +O=C(CCC(=O)c1ccccc1)Nc1cccc(Cl)c1 +CCCCCN(C(=O)c1ccc(N)c(C)c1)C(C)C +CCc1nn(-c2ccc(C(=O)OC)cc2)c2c1CNCC2 +CC(C(=O)NC(C#N)C(C)(C)C)S(=O)(=O)c1ccc(F)cc1 +C#CCOC(=O)C1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1 +Cc1nc(NC(=O)CSc2cc(Cl)ccc2Cl)no1 +Cc1ccc2nc(C(=O)NCCCc3nc(C)cs3)cn2c1 +NC(=O)C1CCN(C(=O)NCCc2ccc(F)cc2)CC1 +CSc1ncccc1C(=O)NC1CCN(c2ncccn2)CC1 +CN(C(=O)CNS(=O)(=O)c1cnn(C)c1)C1CC1 +CC(C)(C)OC(=O)Nc1cc(N)ccc1OCCO +CCCc1n[nH]c(SCC(O)C(F)(F)F)n1 +COc1ccc(NC(C)=O)cc1NS(C)(=O)=O +COc1ccc(NC(=O)NCc2cccc(C)c2)cc1F +Cc1ccc2nc3c(cc2c1)CCN3C(=O)C1CC1 +COc1ccc(-c2cc(=O)n(CCNC(=O)C3CCCC3)cn2)cc1 +Cc1cc(CC(=O)NCC(C)(O)c2cc(C)oc2C)no1 +O=C(NCc1noc(-c2cccc(Cl)c2)n1)C1CCOC1 +COc1ccc(Br)cc1NC(=O)C1CC(=O)N(C)C1 +Cc1cccc(C)c1NC(=O)c1cccc(C#N)c1 +Cc1ccc2[nH]c(SCC(=O)N(C)C3CC3)nc2c1 +CCCc1cc(C(=O)Nc2sc(C)c(CC)c2C#N)no1 +CCN(C)C(=O)c1cccc(C(=O)NC2(C)Cc3ccccc3C2)c1 +Cc1cccc2c1NC(c1ccc(Cl)c(Cl)c1)NC2=O +CC(C)(C)c1nnc(NC(=O)c2cccc(OCC(F)F)n2)s1 +Oc1cccc(Cn2ccnc2C2CCCCC2)c1 +Cc1cccc(C2(C(=O)NCc3c[nH]nc3C)CCCC2)c1 +Nc1ccn(CCCn2nc3n(c2=O)CCCC3)n1 +Cc1nc[nH]c1C(=O)N1CCC(C)(O)C(CC(C)C)C1 +Cc1ccc(NC(=O)COCc2nc3ccccc3s2)c(O)c1 +O=C(C(O)c1ccc(F)cc1)N1CCc2ccccc21 +CCNC(=O)c1ccc(NC(=O)N2CCc3cc(F)ccc3C2)cc1 +Cc1ccccc1N1CCCn2c1nc1c2c(=O)[nH]c(=O)n1C +O=C(CCc1ncc(-c2ccc(F)cc2F)o1)NCc1ccco1 +CC(C)c1n[nH]c(C2CN(C(C)C(=O)Nc3ncccn3)CCO2)n1 +Cc1oc(-c2ccccc2)nc1CS(=O)(=O)c1ncc(CO)n1C +Cc1ccc(S(N)(=O)=O)c(C(=O)N(C2CC2)C(C)C2CC2)c1 +CN(Cc1cccc(O)c1)C(=O)c1cccc(-c2noc(C3CC3)n2)c1 +CCC(NC(=O)c1ccnc(-n2ccnc2)c1)C(C)C +Cc1n[nH]c(C)c1CNCc1ccccc1S(=O)(=O)N(C)C +O=C(Nc1ccc(CCC(=O)N2CCCC2)cc1)OCC(F)(F)F +COc1ccc(CC(=O)NC2(c3ccccc3)CCOCC2)cc1 +C=CCC1(CO)CCCN(C(=O)c2ccc(N3CCCC3)cc2)C1 +CC(OCC(O)CNC(=O)c1cccc(Cl)c1)c1ccccc1 +Cc1nscc1C(=O)C(C#N)c1nnc(-c2ccccc2)n1C +Cc1nn(-c2ccccc2)cc1CN1CCNC(=O)C1C(C)C +Cc1ccnc2nc(C(=O)OCC(=O)NCCc3ccccc3)nn12 +Cc1cccc(CN2C(=O)CCC3C2CCN3C(=O)CC2CC2)n1 +N#CC(C(=O)c1cccc(-n2cccc2)c1)c1nnc2n1CCCCC2 +COc1ccccc1CC(=O)NCCNC(=O)c1ccco1 +CCOC(=O)c1ncn(Cc2ccc3c(c2)OCO3)c1N +Cc1nc(CNC(=O)c2ccccc2Br)no1 +CCN(CC1CCCO1)C(=O)C(NC(C)=O)C(C)C +Cc1c(CCC(=O)N(Cc2ccco2)CC2CCCO2)cnn1C +CC(=O)NC(C(=O)Nc1cc(-c2ncco2)ccc1C)C1CCCC1 +Cc1ccc(NC(=O)CSc2nnc(-c3cccnc3)s2)cc1 +CCN(Cc1ccccc1)C(=O)C1CCC2(CC1)N=C(C)N(C)C2=O +Cc1cc(NC(=O)c2cc(Cl)c[nH]2)c2ncccc2c1 +NC(=O)C1C2CCC(C2)C1NC(=O)CC1OCCc2ccccc21 +CC1(C2CCN(C(=O)NC3CCC(O)CC3)CC2)OCCO1 +Nc1cccc(-n2ccnc2C(=O)Nc2ccccc2F)c1 +O=C(Cn1ccccc1=O)N1CCC(CCn2cccn2)CC1 +CCOC(=O)c1cc2sc(N(C)C)nc2s1 +OC(CN1CCOCC1)c1ccc(-c2ccnc3[nH]ccc23)cc1 +CC(NC(=O)c1cccc(N2CCOC2=O)c1)c1cccnc1 +Cc1oc(C)c(S(N)(=O)=O)c1C(=O)NC1CCCC1 +CC(=O)Nc1ccc(C(=O)Nc2nc(C)no2)cc1 +N#Cc1cccnc1N1CCCN(C(=O)Cc2ccc[nH]2)CC1 +CCC(C)NC(=O)CCNC(=O)Nc1cccc(Cl)c1 +Cc1cc(CNC(=O)c2cc(S(C)(=O)=O)ccc2C)ccc1F +NC(=O)C1CN(Cc2ccc(Cl)c(C(F)(F)F)c2)CCO1 +C=CCC1C=CCC(CC=C)N1C(=O)c1cnn2c1CCCC2 +CCN(CC(F)(F)F)S(=O)(=O)c1ccc(F)c(F)c1 +Cc1ccc(C#N)c(N2CC(NS(C)(=O)=O)C(C(C)C)C2)n1 +CCC(C#N)CC(=O)Nc1ccccc1OC(C)C +CC(CN(C)C(=O)C(O)c1ccccc1)c1nccs1 +Cc1cc(NC(=O)CNC(=O)C(C)(C)C)ccc1C(=O)N(C)C +COc1ccc(S(=O)(=O)NC(C)c2ccc(C)o2)cc1C(N)=O +COc1ccsc1C(=O)NCCCCC(C)C +Cc1nc(N2CCOCC2)nc2c1CN(C(=O)NC(C)C)CC2 +Fc1cccc(NCc2ccccc2OC(F)F)n1 +Cc1cc2cc(C(=O)NC3CCN(c4cnccn4)CC3)ccc2o1 +Cc1cc(C)c(C(=O)NCc2sccc2C)c(=O)[nH]1 +Cc1ccc(O)c(-c2nc(C)nn2-c2ccc3c(c2)OCO3)c1 +O=c1c2cnn(-c3ccc(F)cc3)c2ncn1C1CCCC1 +N#CCCN(CC(=O)Nc1ccccc1N)c1ccccc1 +O=C(CNC(=O)c1ccc(SC(F)F)cc1)NCc1ccco1 +COc1ccccc1-n1ccn2cc(-c3ccccc3C)nc2c1=O +CC(=O)c1ccc(OCc2cc(C(=O)N(C)CCO)no2)cc1 +O=C(CN1CCOCC1)N1CCCC(Cc2ccccn2)C1 +Cc1nn(-c2ccncn2)c2oc(=O)cc(C(F)(F)F)c12 +CCOC(CC)C(=O)Nc1nnc(-c2ccco2)s1 +COc1ccc(C(C)NC(=O)c2ccc(F)cc2)cc1F +Cn1cc(CC(=O)Nc2ccccc2-n2cnnn2)c2ccccc21 +CCCNC(=O)Cn1cnc2c(c(C)c(C)n2-c2ccccc2)c1=O +CC(C)(C)c1n[nH]cc1CN1CCOC(c2cccs2)C1 +C=CCNC(=O)CSc1nc(NCC)c2ccccc2n1 +CC(C)CC(=O)c1ccc(S(=O)(=O)CCO)cc1 +Cc1cccc(C2C3=C(COC3=O)Nc3c2c(=O)n(C)c(=O)n3C)c1 +O=C(CN1CCN(c2ccc(Cl)cc2)C1=O)NC1CC1 +COC(=O)c1cc(CNS(=O)(=O)C(C)C)ccc1OC +COC(=O)c1ccc(COC(=O)c2cccc(OC)c2)o1 +Cc1c(NC(=O)C2CCCCC2)cccc1-n1cnnn1 +CCOc1cc(CO)ccc1OC1CCOC1=O +CC(C)N1CC(C(=O)NCCc2ccc(C(F)(F)F)cc2)CC1=O +CCc1nnc2sc(-c3cc4ccccc4o3)nn12 +CCOC(=O)c1cc2c(=O)oc3ccccc3c2oc1=O +CCCCN(C)S(=O)(=O)c1cc(C(=O)CC)ccc1F +COc1ccccc1C=CCN1CCOC(C)(C)C1 +Cc1ccc2oc(Nc3nc(C)cc(=O)[nH]3)nc2c1 +CCOC(=O)CCn1c(=O)oc2cccc(N)c21 +CCC(C)(C)NC(=O)c1ccc(NC(=O)C2CC2)cc1 +O=C(NC1CCc2c(Cl)cccc21)c1ccco1 +CCn1ncnc1-c1nccn1CCC1=CCCCC1 +COC(=O)c1ccc2c(c1)nc(C(F)(F)F)n2CCO +CCNC(=O)CSc1nncn1-c1ccccc1OC +COC(=O)c1cccc(C(=O)N2CCOCC2(C)C)n1 +CN(C)c1ccc(NC(=O)C2CC3CCC2O3)cn1 +CC1CC(C)CN(C(=O)Cn2c(=O)sc3ccccc32)C1 +COc1ccc(C(=O)N2CCOC(C)(C)C2)cc1OC +CS(=O)(=O)N1CC2COCC2(CN2CCOCC2)C1 +CC(=O)NC(c1ccc(F)cc1)c1ccc(C#N)cc1 +CC(C)Oc1ncnc2c1CCN(C(=O)C1CCCO1)CC2 +Cc1nnc(COC(=O)COc2ccc3oc4ccccc4c3c2)o1 +CS(=O)(=O)N1CC(n2cc(-c3ccccc3)nn2)C1 +CC(=O)Nc1ccc(C)cc1NC(=O)c1oc2ccc(F)cc2c1C +CCCN(C)C(=O)c1csc(NC(=O)c2ccc3c(c2)OCO3)n1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1cccc(C)n1 +Cc1csc(C(C#N)C(=O)c2cnn(-c3ccc(Cl)cc3)c2)n1 +CC(=O)Nc1ccccc1C(=O)OCC(=O)NC1CCCC(C)C1C +O=C(CN1CCN(c2ccc(O)cc2)CC1)NCCc1ccccc1 +NC(=O)C1CCCN(C(=O)CNc2ccc(F)cc2)C1 +Cc1cc(C(=O)Nc2ccnn2C(C)C)cc(S(N)(=O)=O)c1C +CC(C)Cc1c(CO)nnn1-c1cccc2c(O)cccc12 +Cc1cccc(NC(=O)C2CCN(c3nc(C)ns3)CC2)n1 +N#Cc1ccccc1N1CCN(C(=O)c2cccc(F)c2)CC1 +COc1cccc(NC(=O)NCC#Cc2ccc(F)cc2)c1OC +COc1ccc(CNC(=O)Cn2nnc3ccccc32)cc1OC +CCn1nc(C)cc1C(=O)Nc1nc(-c2cccc(OC)c2)cs1 +CCCCNC(=O)c1c(N)oc2ccc(Cl)cc2c1=O +CCOC1CCN(C(=O)Nc2nn(-c3ccccc3)cc2C)CC1 +CN(C)C(=O)C1(CNC(=O)NCc2ncn(C)n2)CCCC1 +CCc1ccc(-c2nccn2CC2(O)CCCCC2)nc1 +O=C(NCC#Cc1ccc(N2CCOC2=O)cc1)c1ccc(=O)[nH]c1 +CC(C)(C)n1nc(C(=O)N2CCC(C(N)=O)CC2)cc1C1CC1 +CNC(=O)CN1CCN(c2nc3ccccc3s2)CC1 +O=C(Nc1ccccc1O)c1cnc(Cc2ccccc2)s1 +FC(F)(F)c1cnc2c(-c3ccccc3)noc2c1 +CCOc1ccc(CNC(=O)c2ccc(N3CCOCC3)cc2)cc1 +CC(C)C1COC2(CCCN(C(=O)c3ccc(O)cc3)C2)C1 +CCOc1ncccc1C(=O)NCc1ccc(C)cc1 +Cc1ccc(-c2nc3cccnc3o2)cc1NC(=O)C(C)C +Cc1onc(-c2c(F)cccc2Cl)c1C(=O)n1cccn1 +O=C(c1ccc[nH]1)N1CCC2(CC(=O)N(c3ccccc3)C2)C1 +CCC(C)c1nc2ccc(Cl)cc2n1CC(C)O +COc1ccc(C(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1C +CC(=O)c1c[nH]c(C(=O)NCCCN(C)S(C)(=O)=O)c1 +CC(=O)c1ccccc1NC(=O)COC(=O)c1ccc(O)cc1 +CN(CC1CC1)C(=O)NCC(c1ccccc1)N1CCOCC1 +Cc1noc2ncc(C(=O)NC3CCN(C(=O)CC(C)C)CC3)cc12 +Cc1ccc(OCC(=O)Nc2ccc(Cl)cn2)cc1 +Cc1c(C(=O)NCCOc2cccnc2)oc2c1C(=O)CC(C)(C)C2 +c1nc(N2CCc3sccc3C2)c2ccsc2n1 +CCC(NC(=O)C(C)NC(=O)c1ccccc1)c1cccc(Cl)c1 +Cc1ccncc1NC(=O)NC(C)c1ccc(C#N)cc1 +COC(=O)c1cc(NC(=O)c2ccccc2C)cc(C(=O)OC)c1 +O=C(CCc1c[nH]c2ccccc12)NCc1ccccc1F +Cc1ccc(OCCOc2c(C)occc2=O)cc1 +CCc1c(C(=O)NC(C)c2c(C)noc2C)cnn1-c1ccccc1 +CN1c2cnc(N3CCOCC3)nc2-c2sccc2S1(=O)=O +CN(Cc1ncc[nH]1)C(=O)COc1ccc(F)cc1 +Cc1noc(C)c1S(=O)(=O)NCc1cccc(OCC(C)C)c1 +COC(=O)c1cc(CN2CCCC(c3nc(C)no3)C2)c[nH]1 +N#Cc1ccccc1NCC(O)c1ccc2c(c1)OCCCO2 +CNC(=O)CCCC(O)c1cc(C(C)(C)C)ccc1C +O=C(NCCO)C1CCCN(C2=NC=NC3=NC=NC32)C1 +CC(C)c1ccccc1NCc1nccn1C(F)F +CCC(C)Oc1cccc(-c2cnn(CC)c(=O)c2CO)c1 +CC(C)N1CC(C(=O)Nc2nc(C(C)(C)C)cs2)CC1=O +COc1ccc(SCCC(=O)N(C(C)C)C(C)C)cc1 +O=C(c1c[nH]nc1-c1ccccc1)N(Cc1nccs1)C1CC1 +COCC(=O)Nc1ccccc1C(=O)N1CCCCC1 +CCOC(=O)N1CCN(c2cncc(C(N)=O)n2)CC1 +O=C(CNC(=O)c1cc2c(s1)CCCC2)NCc1ccsc1 +COc1ccc2cccc(CC(=O)N(c3cnn(C)c3)C(C)C)c2c1 +Cc1ccn2cc(COc3ccccc3N)nc2c1 +NC(=O)CCSc1ccccc1NC(=O)N1CCCC2CCCC21 +CC1CN(C(=O)CSc2ccc(F)cc2F)CCO1 +COC(=O)C1CC2CCCCC2N1C(=O)c1ccoc1C +CN(CCNC(=O)CC1CC2C=CC1C2)S(C)(=O)=O +COc1ccc(F)cc1S(=O)(=O)NCc1ccncc1 +Cn1nccc1C(=O)Nc1ccccc1-c1nc2ccccc2[nH]1 +CC1(C)CCc2cc(CC(=O)Nc3nccs3)ccc2O1 +c1ccc(-n2ncc3c2ncn2nc(-c4ccncc4)nc32)cc1 +CN(C)C(C(=O)Nc1nccs1)c1c(F)cccc1Cl +Cc1cc(Cl)ccc1OC(C)C(=O)NCCNC(=O)C(C)C +CCOC(=O)c1cc2c(=O)[nH]c(=O)n(CC)c2nc1C +COc1ccc(CC(=O)Nc2ccccc2C(=O)C(C)C)cc1OC +Cc1ccccc1NCCC(=O)Nc1cccc(C(=O)N(C)C)c1 +Cc1cccc(CC(=O)NC(C)c2c(C)noc2C)c1 +COc1ncnc(OC)c1CNc1cccc(F)c1 +COc1cc(C)c(C)cc1S(=O)(=O)N1Cc2cncnc2C1 +Cc1ccn(CC(=O)NC(C)c2ccc(Cl)cc2)c(=O)c1C#N +CN(Cc1ccccc1)C(=O)COC(=O)c1cc2c(s1)CCC2 +Cc1ccc(Cn2nccc2NC(=O)C(C)Sc2ccccc2)o1 +CSc1nnc(N)n1CC(=O)Nc1nc(C)c(C(C)=O)s1 +O=C(COc1cccc(C(F)(F)F)c1)Nc1ccon1 +Cc1n[nH]cc1NC(=O)c1cc(F)cc2[nH]cnc12 +CC(C)Cc1nc(C(=O)NCc2ccc(O)cc2)cs1 +COc1cc(C(O)C2CCCC2)cc(OC)c1OC +Cc1ccccc1S(=O)(=O)N(CCO)C1CC1 +N#Cc1cc(NC(=O)N(Cc2cccs2)C2CC2)ccc1F +CC(N)C(=O)c1ccc2c(c1)CCCS2(=O)=O +O=C(Nc1ccccc1F)NC1CCOc2c(Cl)cccc21 +COc1ccc(-c2nonc2NC(=O)COc2ccccc2)cc1 +CNC(=O)Cc1ccc(-c2ccc(-n3cccn3)cc2)cc1 +CN(C)C(=O)Cn1cc(C(=O)N2CCCc3cccc(F)c32)nn1 +COc1ccc(Cl)cc1C(=O)NCC1(O)CCCC1 +CC(=O)NCC1CCN(S(=O)(=O)c2cc(C)cc(F)c2)CC1 +COc1cccc(CCNC(=O)C(c2cccnc2)N2CCCC2)c1 +Cc1nn(CCCc2ccccc2)c2c1C(=O)CCC2 +CCCNC(=O)c1nc2cc(C)c(C)cc2n(C)c1=O +CC(=O)NCCNS(=O)(=O)c1cc(Br)ccc1C +COc1ccccc1CCNC(=O)c1c(-c2ccccc2)noc1C +Cc1cc(C(=O)CSc2nnnn2C)c(C)n1CC1CCCO1 +Cn1nc(C(=O)N2CCOCC2)cc1NC(=O)c1ccccc1 +Cc1cccc(NC(=O)CS(=O)(=O)c2ccccc2)c1 +Cc1nnc(SCc2nc3ccccc3c3ccccc23)n1N +O=C1CC2C(CCN2Cc2cccs2)N1CCO +Nc1cccc2c(NCc3ccco3)ncc(Br)c12 +Cc1cc(C(=O)Oc2cccc(C(=O)NC3CC3)c2)c(C)s1 +O=C(NCCCOC1CCCCC1)c1cc(C2CC2)on1 +COC(=O)c1ccc(CNC(=O)N2CCCC2)cc1 +Cc1nc(C)n(CC2CCCN2Cc2ccc(F)cc2C#N)n1 +CCOC(=O)CCC1NCCc2ccc(O)c(Cl)c21 +Cn1nccc1C(=O)NCC(=O)N1CCc2ccccc2C1 +Cc1ccc(N2CCCN(C(=O)c3cc(C)sc3C)CC2)nn1 +Cc1c(C(=O)NC2CCc3c(O)cccc32)cnn1-c1ccncc1 +CCNC(=O)c1cc(S(=O)(=O)Nc2cccc(C)c2)ccc1C +Cn1nc(-c2cccs2)n(-c2ccncc2)c1=O +CC1Cc2ccccc2N1CCNS(=O)(=O)N(C)C +CC(C)(C)c1noc(CCC(=O)Nc2cc[nH]n2)n1 +Cc1[nH]c2nc(N3CCCCC3C)nn2c(=O)c1CCO +O=C(CCCc1cccs1)Nc1ccccc1Cn1cncn1 +COC(=O)c1cccc(CCNC(=O)Nc2ccc3c(c2)COC3)c1 +CNc1cnc(N(C)CCO)c2cc(F)c(F)c(F)c12 +O=C(Cc1ccc(F)cc1F)Nc1ccccc1N1CCCC1=O +N#CCOc1cccc(CC(=O)Nc2cccc(NC(N)=O)c2)c1 +Nc1cccc(NC(=O)CSc2ccccc2Br)c1 +CC(=O)N1CCCC(COc2cccc(C(=O)NC3CC3)c2)C1 +Nc1ccc(SCc2ccc3c(c2)OCO3)cc1 +Cc1cc(C(=O)Nc2cccc(NS(N)(=O)=O)c2)ccc1F +Cn1ccnc(NC(c2ccccc2)C2CCC2)c1=O +CCC1(CNC(=O)NC(c2ccc(OC)cc2)C2CCOCC2)CC1 +COC(=O)c1cc(OC)c2c(O)c(OC)c(OC)cc2c1 +CN(C)C(=O)COC(=O)CCc1nc2ccccc2c(=O)[nH]1 +N#Cc1ccc(-c2noc(-c3cc(F)cc(Br)c3)n2)nc1 +O=C(Nc1nnc(SCc2ccccc2F)s1)C1CCCO1 +COc1cc2c(cc1C)C(c1sccc1C)CC(=O)N2 +CCOc1ccccc1OCC1NCCc2ccc(O)cc21 +COc1cccc(N2CCN(C(=O)C3CC3)C(C)C2=O)c1 +Fc1cncc(C2NCCc3cc4[nH]ccc4cc32)c1 +CCS(=O)(=O)NCCCNC(=O)NC1CCC(C)CC1 +CC1CCN(S(=O)(=O)N2CCN(c3ccccn3)CC2)CC1 +CC(NC(=O)Cc1cccs1)c1nc2cccnc2n1C(C)C +O=C(NCc1cccs1)c1cc(F)ccc1Br +Brc1cc(-c2ccccn2)cn2cnnc12 +O=C(C1CC(=O)N(c2n[nH]c3ccccc23)C1)N1CCOCC1 +COC(=O)c1ccc(Cl)c(NC(=O)c2cccc(N)c2C)c1 +O=C1CCc2ccc(NC(=O)N3CCCC4CCCC43)cc2N1 +CCc1cccc2c(CCNC(=O)NC3CCC(O)CC3)c[nH]c12 +CC(C)c1nnc(NC(=O)c2cc(Br)cn2C)s1 +CCCC1CN(Cc2cnc3nc(C)cc(C)n23)CCO1 +N#Cc1ccccc1CN1CCN(c2nccs2)CC1 +CCN(Cc1ccccc1NC(=O)CCc1ccsc1)C(C)=O +CCOC(=O)C(C)Sc1nnc(-c2cccs2)n1C1CC1 +O=C(NC1CCCCC1)NC1CCN(C(=O)Nc2cn[nH]c2)CC1 +COC(=O)C1(NC(=O)c2cc(-c3ccccc3F)on2)CCCC1 +COc1ccc(CCN2CC(CO)CC2=O)cc1OC +COc1ccccc1C(=O)N1CCCC(c2nnc(C)s2)C1 +CCc1n[nH]c(NC(=O)c2cnc3ccc(C)cn23)c1Br +CCNC(=O)N1CCC(NC(=O)N2CCc3cc(F)ccc3C2)C1 +CC(=O)NCCNC(=O)NCC(C)(C)c1ccc(C)cc1 +O=C(Nc1c[nH]c(=O)[nH]c1=O)c1ccccc1Cl +CCCc1nc2ccccc2n2cc3c(=O)n(C)c(=O)n(C)c3c12 +Cc1ccc(-c2cccc(-c3ccn(Cc4ccncc4)n3)c2)cn1 +COc1ccc(NC(=O)Cc2cc(Cl)c3c(c2)OCCO3)cc1 +CCN(CC)S(=O)(=O)N1CCCC1c1ccc(F)cc1 +N#CCCCSc1nc(-c2ccccc2)nc2ccc(F)cc12 +O=C(CC12CC3CC(CC(C3)C1)C2)NCC(=O)N1CCCCCC1 +CCn1cc(-c2nn3c(-c4cc(F)ccc4F)nnc3s2)cn1 +COc1cccc2c1OCC(NC(=O)CCc1ccc(F)cc1)C2 +Fc1ccccc1N1CCC(N2CCOC(C(F)(F)F)C2)CC1 +CC1CC(C)CN(C(=O)COCc2nc(-c3ccncc3)no2)C1 +COc1ccc(CNC(=O)c2cnc3cc(C)ccn3c2=O)cc1O +COC(=O)c1ccc(OCC(=O)c2cc(C)[nH]c2C)c(OC)c1 +COc1cc(N)c(C(=O)NCc2ccccc2)cc1OC +Cc1ccncc1NC(=O)NC(C)Cc1ccc(O)cc1 +O=C(CSc1nncn1-c1cccc(Cl)c1)NCc1ccco1 +O=C(NCc1c(F)cccc1Cl)c1cnc2[nH]ccc2c1 +CN(C)C(=O)COc1cc(C(=O)NCc2ccncc2)nn1C +O=C(NCC#CCOc1ccccc1Cl)c1ccc(=O)oc1 +O=C(NCCCOCC1CCOCC1)C1CCCCC1 +CCCc1nnc(NC(=O)c2scnc2C2CC2)s1 +CC(=O)N(CCc1ccccc1)CC(=O)Nn1cnc2ccccc21 +Cc1nc(N(C)C)ncc1C(=O)NCc1cnn2cccnc12 +Cc1ccc(C)c(OC(C)C(=O)N(C)CC2(CO)CCOCC2)c1 +COc1ccc(OC)c(NCC(=O)c2cccs2)c1 +CS(=O)(=O)c1ccc(CN)cc1C(F)(F)F +NS(=O)(=O)N1CCCN(C(=O)c2cccc(-n3cccc3)c2)CC1 +Cc1cc(OCn2cc(Cl)c(N)n2)ccc1Cl +CN1C(=O)CCc2cc(C(=O)Nc3cn(C)c(=O)n(C)c3=O)ccc21 +CN(Cc1ccc(Oc2ccccc2)cc1)C(=O)CO +Cc1noc(N)c1C(=O)OCc1csc(-c2ccc(F)cc2)n1 +CCN(CC)C(=O)N1CCN(C(=O)Nc2ccccc2)CC1 +CCN(CCO)C(=O)Nc1ccccc1N1CCCC1=O +COc1cc2c(cc1F)CCNC2c1cncnc1 +Cc1ccc(-c2ccc(OCCNS(=O)(=O)N(C)C)nn2)cc1 +COCCOc1cc(NCc2ccccc2)nc(C)n1 +CCCc1cc(C(=O)Nc2ccc(OC)c(OC)c2)n(C)n1 +O=C(Cn1cc(Cl)cn1)N1CCCC(Cc2cccnc2)C1 +Cc1nc(SCC(=O)Nc2ccccc2)c2ccccc2n1 +CC(CO)NC(=O)Cc1ccc(-c2ccccc2)cc1 +Cn1c(=O)c(C(=O)N2CCCCC2)nc2cccnc21 +COc1c(C)cnc(CNS(=O)(=O)c2ccc(F)cc2C)c1C +CC(CCOc1ccccc1)C(=O)N1CCc2[nH]ncc2C1 +C=CCN(Cc1ccccc1)C(=O)c1ccc(S(N)(=O)=O)o1 +COC(=O)c1ccccc1NC(=O)CNC(=O)c1cn(C)nc1OC +COCCCNc1nc2cc(S(C)(=O)=O)ccc2n2ccnc12 +Cc1sc2nc(SCc3cc(O)n[nH]3)nc(N)c2c1C +COc1cc(Cl)c(OC)c2c1CC(CO)CN2 +CC(c1ccco1)N(C(=O)Nc1ccccc1)C1CC1 +CCn1nc(C)c(NC(=O)CN2C(=O)C(C)(C)c3ccccc32)c1C +Cc1noc(C2CCCN2C(=O)c2csc(C)n2)n1 +CC(C)n1nc(C(=O)N(C)Cc2cccnc2)c2ccccc2c1=O +O=C(c1cc2c(cc1-c1ccc3c(c1)OCCO3)OCCO2)C1CC1 +Cc1ccc2c(n1)OCCN2C(=O)c1cc(-c2ccco2)on1 +Cc1cc(N2CCC3(CCC(=O)N(CCCO)C3)CC2)ncn1 +CCOC(=O)COc1nc(N(C)C)nc(N2CCOCC2)n1 +O=C(C1CCOCC1)N1CCC(c2cnccn2)CC1 +O=C(NCCN1CCCc2ccccc21)C1COCCO1 +CCNC(=O)COC(=O)c1cc(Br)ccc1N +O=C(c1cncc(N2CC3C4CCC(CC4)C3C2)n1)N1CCOCC1 +O=C1c2c(Cl)cc(Cl)cc2OCC1n1ccnc1 +CC(C)c1noc2ncc(-c3nnc(C4CC4)o3)cc12 +Cc1ccc(-n2[nH]c(C(=O)NC3COc4ccccc43)cc2=O)cc1 +Cc1ccccc1C(=O)Nc1cc2c3c(c1)CCN3C(=O)CC2 +Cn1ccc(C(=O)N2CCCC2c2cccc(F)c2)n1 +Cc1cccc(NC(=O)NCC(=O)Nc2cnc3ccccc3c2)c1 +CC(=O)c1cc(C#N)c(SCCCN2CCCC2=O)nc1C +N#CC(C(=O)CCCc1nc2ccccc2s1)c1ccccn1 +Cn1cnnc1C1CCCN(C(=O)c2ccccc2Cl)C1 +CCNC(=O)C1CCN(C(=O)c2cccc(Cl)c2)CC1 +CN(CC(O)C1CC1)C(=O)Cc1csc(NC(=O)C(C)(C)C)n1 +Cc1ccc(OCCNC(=O)c2cn3cccnc3n2)cc1C +Cc1cc(C)n(CCN2CCN(C(=O)c3cccs3)CC2)n1 +Cc1cc(-c2cccs2)oc(=O)c1NC(=O)c1cnccn1 +O=C(CC1CCCC1)Nc1ccc(N2CCOCC2)cn1 +C=CCNC(=O)CSc1nnc(-c2ccc(C)cc2)n1C +Cc1ccc(OCC(=O)Nc2ccccc2N)cc1C +O=C(CCc1ccc(F)c(F)c1)Nc1ccncc1 +Cc1nccn1-c1ccc(NC(=O)c2cc(-c3ccccc3)on2)cn1 +COc1ccc(C(=O)Nc2cnc3c(cnn3C(C)C)c2)cc1F +COCCNC(=O)c1oc(-c2ccccc2)nc1C +Cn1ncc2c1CCCC2NC(=O)NCc1ccc(F)cc1 +Cc1noc(C)c1CN1CCN(C(=O)C2CC(=O)N(C3CC3)C2)CC1 +CCn1c(=O)n(CC(=O)NCCc2ccccc2)c2cccnc21 +CCOC(=O)c1cc(C(=O)Nc2cc(Cl)ccc2C)c(=O)[nH]c1C +COc1cccc(OC)c1-c1cnn(C)c(=O)c1C(C)=O +O=C(NCc1noc(CCc2ccccc2)n1)c1cccc(Cl)c1 +Cc1c(Cl)cccc1NC(=O)Cn1nc(-c2ccco2)ccc1=O +O=C(Nc1ccc(C(=O)N2CCC2c2ccccc2)cc1)NC1CC1 +CC(Sc1nnnn1C)C(=O)Nc1cc(Cl)ccc1Cl +COc1ccc(C2(C(=O)Nn3cnnc3)CCCC2)cc1OC +CC(=O)c1ccc(C)n(Cc2c(Cl)cccc2Cl)c1=O +O=C(c1nn(-c2ccccc2)c2c1CCC2)N1CCC1 +Cc1ccc(NC(=O)c2ccc(Br)cc2)nc1 +CCCc1nc(CN2CCN(S(C)(=O)=O)CC2)cs1 +CCOc1ccccc1CNC(=O)c1nonc1N +Cc1cc(CNC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)c(C)o1 +Cn1c(=O)[nH]c(=O)c2cc(S(=O)(=O)N3CCCCCC3)cnc21 +COc1ccc(Cc2nc3ccccc3c(=O)n2C)cc1N +Cc1noc(C)c1S(=O)(=O)N1CCN(CCn2cccn2)CC1 +N#Cc1cccc(NC(=O)c2nc3ccccc3o2)c1 +Cc1nnc(NC(=O)N(Cc2ccncc2)CC2CCCO2)s1 +Cc1ccc(CC2NCCc3c(N)cc(F)cc32)cc1 +CNC(=O)c1cccc(OC2CC2)c1S(N)(=O)=O +Cc1cccc(CCNC(=O)C2CCN(c3ccc(F)cc3)C2=O)c1 +COC(=O)c1cc(CNC(=O)NC2CCCCC2)ccc1OC +Nc1ccccc1OCCc1nc2c(s1)CCCC2 +CCC1CCCC(NC(=O)c2cc(OC)c(S(N)(=O)=O)s2)C1 +CNC(=O)Nc1cccc(NC(=O)c2n[nH]c3ccc(C)cc23)c1 +Cn1c(=O)oc2cc(NC(=O)Nc3cccc(Cl)c3)ccc21 +COc1ccc(NC(=O)NC(C)c2ccc(S(C)(=O)=O)cc2)cc1 +Cc1nc(CN2C(=O)CCC3C2CCN3Cc2cccs2)cs1 +O=C(NC1CC1)C1CC(=O)N(c2ccccc2Cl)C1 +CN(C(=O)C1Cc2ccccc2C(=O)O1)c1ccccc1 +NC(=O)c1c(NC(=O)c2ccccc2)sc2c1CCc1ccccc1-2 +COCc1oc(-c2ccc(OC)c(OC)c2OC)cc1C#N +CN1CCC(CNC(=O)NCCCn2ccnn2)c2ccccc21 +Cc1cn2nc(N3CCCC3c3cnn(C)c3)sc2n1 +COCCn1nc(C(=O)Nc2ccc(-n3ccnc3)nc2)ccc1=O +CCCn1cc(C(=O)NCCN(C)c2ccccc2)c(C)n1 +Nc1cc(N)nc(SCC(=O)Nc2ccccc2C(F)(F)F)n1 +Cn1cc(CCC(=O)N2CCCC2c2ccc3c(c2)OCCO3)cn1 +NC(=O)CSc1nccc(-c2ccc3c(c2)OCO3)n1 +Cc1cccc(OCC(=O)NCC(C)(O)C2CC2)c1 +NC(=O)c1cccc(COC(=O)Cn2ncc(=O)c3ccccc32)c1 +CC(C#N)Cn1cccc(OCC(=O)N2CCCCCC2)c1=O +CC(C)(C)CC(=O)NCc1ccnc(-n2ccnc2)c1 +CC(=O)N1CCc2nc(C3CCCN(c4ncccn4)C3)ncc2C1 +COc1ccc(S(=O)(=O)Nc2ccncc2)cc1C +COCc1noc(C2(c3ccc(F)cc3)CCOCC2)n1 +Cc1ccc(CNC(=O)Cn2ncccc2=O)cc1 +CCNC(=O)NCc1cccc(OCC(C)C)c1 +N#CC1(NC(=O)COc2cccc(C(N)=O)c2)CCCCC1 +Oc1ccc(Cn2ccnc2-c2ccncc2)cc1 +COc1ccc(O)c2c1C(c1cc[nH]c(=O)c1)NCC2 +COC(=O)CNC(=O)c1nc(C)oc1C(F)(F)F +COc1cc(N)ccc1NS(=O)(=O)c1cn[nH]c1 +CCCCCNC(=O)C1CSc2ncc(C)c(=O)n2C1 +O=C(CSc1ccc(F)c(F)c1)Oc1ccc2c(c1)OCO2 +CC(=O)c1ccc(NC(=O)c2ccc(-c3ccccc3)[nH]c2=O)cc1C +O=C1CN(C(=O)CCOc2ccccc2)c2ccccc2N1 +COc1cccc(Nc2ccc(S(=O)(=O)N3CCOCC3)cn2)c1 +CCc1ccc(C(=O)N2CCN(C(=O)NC(C)CCCO)CC2)cc1 +COc1cccc(C(=O)Nc2nc3c(s2)CN(C(C)C)CC3)c1 +COc1ccc(F)cc1NC(=O)c1cc(-c2csc(C)n2)cn1C +Cc1ccccc1C1(CNC(=O)c2ccsc2)CCOCC1 +CCCCNC(=O)c1snc(-c2cccc(F)c2)c1N +O=S(=O)(c1cccs1)N1CCC(Oc2cnccn2)CC1 +COc1ccccc1NC(=O)C(C)S(=O)(=O)c1ccc(C)c(C)c1 +Cc1[nH]nc(O)c1CCNC(=O)c1nc2ccccc2c(=O)[nH]1 +CC1(C)CCC(CNC(=O)CNC(=O)c2ccc(C#N)cc2)CC1 +Cn1c(C(=O)N2CCN(c3ccccc3)CC2)cc(=O)n(C)c1=O +Cc1cccc(C2CCCN(C(=O)c3cnccn3)C2)n1 +Cc1nc(C)c(-c2cc(C(=O)c3ccco3)c(N)o2)s1 +Cc1ccc(NC(=O)NCc2ccc(S(N)(=O)=O)cc2)cc1F +Cc1ccc(NC(=O)COCC2CC2)cc1NC(=O)C(C)(C)C +O=c1cc(C2CCC2)ncn1Cc1nc(-c2cccs2)no1 +Cc1cc(C)cc(NC(=O)c2ncc3n2CCCC3)c1 +O=C(CCOc1ccc(F)cc1)NCC1CCCO1 +Cc1ccccc1NC(=O)NCc1c(C)nn(-c2ccccc2)c1C +COCC(O)CN(C)c1ncc(CO)cc1Cl +COC(=O)c1cccc(C(=O)Nc2cccc(Oc3ccccc3)c2)n1 +CCOc1cc(C(=O)Nc2ccc3c(c2)CCC(=O)N3)ccc1OC +Cc1noc(CSc2ccccc2C(=O)Nc2cn[nH]c2)n1 +Cc1cc(Cl)ccc1OC(C)C(=O)Nc1c(C)n[nH]c1C +COc1ccc(C(=O)OCC(=O)N2CCCCC2C(N)=O)cc1 +O=C(N1CCCC1)N1CC2COCC2(CN2CCOCC2)C1 +CS(=O)(=O)Nc1ccc(C(=O)Nc2ccc(Cl)cc2)cc1 +CNC(=O)c1ccsc1NC(=O)c1nc2ccccc2s1 +CN1C(=O)CCc2cc(NC(=O)c3ccc(-c4cnco4)cc3)ccc21 +Cc1ccc(-c2nn(-c3ccccc3)cc2C(=O)NCCCO)cc1C +COCCCNC(=O)CN(C)c1ncnc2c1cnn2C +O=C1CC(c2ccc(F)cc2)c2cnn(-c3ccc(F)cc3)c2N1 +O=c1[nH]c2cc3c(cc2cc1CNc1ccc(F)c(Cl)c1)OCO3 +CCN(C(=O)CNC(=O)OC)C(C)c1ccc(F)cc1 +Cc1nc2sc(CCOc3ccccc3)nn2c1CO +O=C(c1ccco1)N1CCCn2c(SCc3ccccc3)nnc21 +CC(=O)c1sc(CNc2c(C)cccc2C)nc1C +CCOc1ncnc2c1sc1nc3c(cc12)COC(C)(C)C3 +Cc1ccc(CC(=O)N2CCCC(C(N)=O)C2)s1 +CCC(CNC(=O)CCn1cncn1)c1ccccc1 +CCNC(=O)N1CCN(CC(=O)NC2CCCC(C)C2C)CC1 +Cn1nc2n(c1=O)CCN(CC(=O)NCCOc1ccc(F)cc1)C2 +Cc1ccc(C)c(-c2cn(-c3cc(N)ccc3C)nn2)c1 +COc1ccc(NC(=O)C2CC2(Cl)Cl)cc1 +COC(=O)c1cccc(NC(=O)Cc2cccnc2)c1 +CC(=O)c1nc2ccc(F)c(F)c2n1-c1ccc(C#N)cn1 +O=C(Nc1cccc2cccnc12)c1cnccn1 +Cc1cc(C)n(CC2CCN(C(=O)COc3ccccc3C)CC2)n1 +CCN(C)C(=O)c1cc(N2CCCC2=O)ccc1Cl +Cc1cc(NC(=O)c2cn(C)nn2)ccc1Br +COCCc1nc(C)c(C(C)Nc2ccc3c(c2)CCC(=O)N3)s1 +COc1ccc(NC(=O)N2CCCC(C)C2CO)c(C)n1 +O=C(CCNC(=O)C12CC3CC(CC(C3)C1)C2)Nc1nncs1 +O=C(CCOc1ccccc1Cl)NCCN1CCOCC1 +Cc1occc1C(=O)NCCNc1ccc(C(F)(F)F)cn1 +Cc1nnc2ccc(S(=O)(=O)Nc3ccccc3)cn12 +C#CCCCCNC(=O)N1CCc2cc(F)ccc2C1 +COc1ccc(CNC(=O)c2cnc3cc(C)ccn3c2=O)cc1 +CC1CN(Cc2n[nH]c(=O)[nH]2)CC(c2ccccc2)O1 +COc1cccc(NCC(O)c2ccc(C)c(N)c2)c1 +CCCN(Cc1cc2ccc(C)cc2[nH]c1=O)C(=O)c1ccc(C)cc1 +CC(=O)Nc1ccc(C(N)C(=O)NCCO)cc1 +O=C(Nc1ccc(F)cc1)c1nnc2cccnn12 +Cc1nc(CC(=O)N=c2[nH]c3ccccc3[nH]2)cs1 +COCCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccco1 +N#CCCN(Cc1ccco1)Cc1ccc(Br)cc1F +O=C(C1CC=CCC1)N1CCOC(c2cccs2)C1 +CCNC(=O)Cn1nc(-c2ccc(Cl)cc2)c(OC)cc1=O +Cc1cccc(S(=O)(=O)CCCc2nc3ccccc3o2)c1 +COc1cccc(C(=O)Nc2ccc(CC(N)=O)cc2)c1 +O=C(NCc1ccoc1)C1CCCCN1C(=O)c1ccco1 +O=C(Nc1cc(-c2ccncc2)n[nH]1)C1(c2ccc(F)cc2)CC1 +O=C(NCc1cccc(CN2CCOCC2)c1)N(CCO)C1CC1 +Nc1cc(F)ccc1NC(=O)CCOCC(F)(F)F +CC(=O)c1cc(CCC(=O)Nc2nccs2)oc1C +COCC(O)CN(C)c1ccc2nnc(-c3ccccc3)n2n1 +CC1NCC(C)(C)c2c(Cl)cc3c(c21)OCCO3 +CC(Nc1ccc(Br)cc1N)c1ccccn1 +O=C(CCCNC(=O)c1ccco1)NCc1ccccn1 +CCOCC1CCCN(C(=O)Cc2ccc(OC(F)F)cc2)C1 +COc1ccc(NC(=O)c2ccc3c(c2)C(=O)CCCO3)cn1 +C=CCn1cc(CNCCc2c(C)n[nH]c2C)c(C)n1 +FC(F)(F)c1ccccc1NCc1cccnc1 +O=c1[nH]c(-c2ccncc2)nc2c1CCN(Cc1ccncc1)CC2 +COCCNC(=O)COc1ccc(C)cc1C(C)O +O=C1NC2(O)C(=O)c3ccccc3C2(O)N1c1ccccc1 +Cc1occc1CN(C)C(=O)CCCCNC(N)=O +CCOc1ccc(C(=O)Nc2sc(C(=O)OC)c(C)c2C#N)cc1 +CN(CCOCC1CC1)C(=O)C(C)(C)c1ccccc1F +Cc1ccc(NCC(=O)NC(C)c2ccco2)cc1-n1cnnn1 +CCN(CCO)c1ncnc(Nc2cccc(Cl)c2Cl)c1N +N#Cc1ncn(Cc2nccn2Cc2ccccc2)c1C#N +COc1ccc(OC)c(C(=O)CCC(=O)N2CCOCC2)c1 +CC1(C)CC(=O)C(C2(O)C(=O)Nc3ccccc32)CO1 +CC(C#N)CNS(=O)(=O)c1ccccc1Br +O=C(Nc1ccc(OC(F)F)cc1)c1cc(-c2ccccc2O)n[nH]1 +CCc1nc(-c2ccc(C(=O)NCc3ncn(C)n3)cc2)n[nH]1 +CC(c1ccccn1)N1CCN(C(=O)c2ccc[nH]2)CC1 +N#Cc1ccc(CN2C(=O)OCC2C(=O)NCc2cccnc2)cc1 +CCC(=O)N1CCCCC1c1nc(N)ncc1-c1cccc(OC)c1 +CC(C)(CNC(=O)c1ccc(CCNC(N)=O)cc1)c1ccncc1 +CCn1cnnc1CNC(=O)NCC1CCN(c2ccccc2)C1 +Cc1ccc(CC(=O)Nc2nc(C)c(SCC(N)=O)s2)cn1 +CCCS(=O)(=O)N1CCCC(C(=O)N2CCOC(C)(C)C2)C1 +Nc1ccc(F)c(NC(=O)Cc2noc3ccccc23)c1 +CC(Oc1cccc(C#N)c1)C(=O)Nc1cc(C#N)ccc1Cl +Cc1nc(C)c(CC(=O)OCc2cc3c(Cl)cccc3[nH]2)c(=O)[nH]1 +Cc1cnn(CC2CC2)c1NC(=O)c1ccccc1F +C=CCN(CC1CCCCC1)C(=O)c1cc(C)no1 +CCCS(=O)(=O)Nc1ccc2c(c1)N(C(=O)c1ccco1)CC2 +COc1ncnc2c1CCN(C(=O)c1ccc(C)o1)CC2 +C#CCOC(=O)CCC(=O)c1ccc(Cl)cc1 +O=c1c2cc(-c3ccc(F)cc3)nn2cnn1Cc1cccc(F)c1 +CCOc1ccc(NC(=O)C2CC(=O)N(C)C2)c(C)c1 +Cc1nnc(CNc2ccc(Br)cc2C(C)C)n1C1CC1 +Cc1nccc(CNC(=O)c2ccccc2NC(=O)C(C)(C)C)n1 +O=C1CC(C(=O)NCC2Cc3ccccc3O2)c2ccccc2N1 +CCOc1ccc2c(C(=O)NCCc3cccs3)cc(=O)oc2c1 +COC(C)(C)C(O)COc1c2occc2cc2ccc(=O)oc12 +CC1=CCC2CN(C(=O)CCn3nnc4ccccc43)CC2C1 +CCOC(=O)c1sc(NC(=O)c2cc(C)oc2C)nc1C +CC(C1CC1)N(C)C(=O)NC1CCN(S(=O)(=O)C2CC2)CC1 +Cc1ccc(Nc2nnc(SCC(N)=O)s2)c(C)c1 +COc1cc(C(=O)NC(CO)C(C)C)ccc1Cl +Cc1cc(C)cc(C(=O)NCC(=O)NCc2cccnc2)c1 +COCCN1CCN(Cc2nc(-c3ccc(C)c(F)c3)no2)CC1=O +COc1ccc(OC)c(NC(=O)COC(=O)c2c(C)noc2C)c1 +COc1cc(NCc2cn[nH]c2-c2cccs2)ncn1 +O=C(Cc1ccc2c(c1)OCO2)Nc1ccc(Oc2ncccn2)cc1 +CCCCOCCn1nc(C)c(Br)c1C +CC1CCCCN1C(=O)Cn1nc2c(cc1=O)CCCC2 +CNS(=O)(=O)C1CCCN(c2c(Cl)cccc2C#N)C1 +O=C(Oc1cccc(-n2cnnn2)c1)c1ccccc1Cl +COc1ccnc(N2CCC(C(=O)NCCNC(=O)C3CC3)CC2)n1 +COc1ccc(OC)c(CNC(=O)c2[nH]nc3c2COCC3)c1 +CCNC(=O)c1ccc(NCC(=O)N(CC)c2ccccc2)cc1 +Cn1c(=O)[nH]c(=O)c2[nH]c(N3CCC(Cc4ccccc4)CC3)nc21 +CCCOCc1ccccc1CNC(=O)c1cc(C)no1 +O=C(CNC(=O)c1c[nH]cc1-c1ccc(F)cc1)Nc1cccnc1 +Cc1ccc(-n2nnnc2CNC(=O)Nc2cccc(C)c2)cc1 +Cc1cccc(OCC(C)NC(=O)Cn2ccccc2=O)c1 +O=S(=O)(Cc1ccon1)NC1CCCCCC1 +CCNC(=O)c1cc2ccc(OC(=O)C3CCCCC3)cc2oc1=O +CCn1c(C)nnc1SCC(=O)Nc1nccs1 +COc1cc(C#N)ccc1OCC(=O)c1ccc(NC(N)=O)cc1 +CC(C)C(O)C1NCCc2cc(F)cc(C(F)(F)F)c21 +O=C(CC1C=CCC1)OCc1nnnn1-c1ccccc1 +CCC(COC)NC(=O)c1n[nH]c(=O)c2ccccc12 +Cc1ccc(-c2csc3ncnc(OCC#N)c23)cc1 +CCOc1cccc2c1C(C(CO)c1ccccc1)NCC2 +Cc1nc2nc(N)nn2c(C)c1CC(=O)NCCCCC(C)C +CCC(CO)NC(=O)c1oc2ccc(F)cc2c1C +CC1CC(C(N)=O)c2ccccc2N1C(=O)C1Cc2ccccc2O1 +CC(=O)Oc1ccc2oc(C)c(C(=O)NCc3ccccc3)c2c1 +Cc1cc(C)c(C(=O)NCCC(=O)NC2CCCC2)c(C)c1 +CN(C)C(=O)c1cccc(CNc2cccc(F)n2)c1 +COc1ccc(-c2cc(C(=O)NCc3csnn3)no2)cc1 +COC(=O)C1CCCC1NC(=O)c1cccc(-c2ccoc2)c1 +O=C1C2CCC(CN(Cc3ccc(Cl)cc3F)C2)N1CC1CC1 +O=C(c1ccoc1)N1CCc2ncnc(-c3cccc(F)c3)c2CC1 +N#Cc1ccccc1N1CCCN(C(=O)CNC(=O)C2CC2)CC1 +CC(=O)NC(c1ccc2c(c1)OCCCO2)C(C)C +CC(=O)NC1Cc2ccccc2C1NC(=O)Nc1cnn(C)c1C +Cc1cc(C(=O)Nc2ccc(C)c(C(N)=O)c2)ccc1F +N#Cc1ccc(C(=O)NCC2CCN(C(=O)c3cccnc3)CC2)cc1 +CC(NC(=O)c1cccc(N(C)C)c1)C(=O)NCc1ccccc1 +Cc1nnc2n1CCN(Cc1nc3ccccc3o1)C2 +CC(C)C(NC(N)=O)C(=O)NC1CCN(c2ccccc2)CC1 +CNS(=O)(=O)c1ccc(-c2nccn2C2CCN(C)C2=O)cc1 +Cn1c(=O)n(CC(=O)N2CCCC2)c2ccccc21 +CCOC(=O)c1ccc(N2CCCC(c3nncn3C)C2)nc1 +Cc1cccc2c(=O)[nH]c(CSc3nc4ccccc4[nH]3)nc12 +CCC(C)NC(=O)c1ccc(-c2cccc(OC)c2)nc1N +Cn1c(Cn2c(=O)c(C#N)c3n(c2=O)CCC3)cc(=O)n(C)c1=O +CCS(=O)(=O)c1ccccc1C(=O)Nc1nccn2ccnc12 +Cc1cccc(NC(=O)COc2ccc(-c3nnco3)cc2)c1 +Cn1cnc(-c2noc(CCc3nc4ccccc4[nH]3)n2)c1 +CC1CN(CC(=O)NC2CCOc3ccccc32)c2ccccc21 +CC(NC(=O)CCCOc1ccccc1F)c1nnc2ccccn12 +CC(C)CC(=O)N1CC2CC3C(C1)(CN(CC(C)C)S3(=O)=O)O2 +Cc1ccc2c(c1)NCC(=O)N2CC(=O)OCC(C)C +CC1CN(CC(=O)NC2CCCC2)CC(c2ccccc2)O1 +O=C(CCCc1ccccc1)NCc1cccc(N2CCOC2=O)c1 +Cn1cnc(CNC(=O)NC2(c3ccc(F)cc3F)CCCC2)n1 +Cc1nc(CN2CCOC3CC(COCC4CC4)CC32)cs1 +COc1ccc(OS(=O)(=O)c2ccc(F)cc2F)cc1 +CC(C)(C)NC(=O)Cc1cccc(Br)c1 +O=C(OC(C(=O)NC1CCCCC1)c1ccccn1)c1cccs1 +CC(=O)NCc1ccc(C(=O)N2CCCc3ccc(Cl)c(C)c32)o1 +COc1ccnc(NC(=O)CC(C)(C)c2ccccc2)c1 +O=C(NC1=CC2N=CC=C2C=C1)c1cc(=O)[nH]c2ccccc12 +CC(=O)c1c[nH]c(C(=O)Nc2nnc3ccccn23)c1 +Cc1ccc2nc(C(=O)N3CCN(c4nccs4)CC3)cn2c1 +Cc1cc(C)c2nnc(C(=O)NC3CCCC3)n2n1 +CCc1oc(C(=O)NC(CCO)c2cccs2)cc1C +COC(=O)CCN(C)C(=O)c1ccc(Br)cc1C +Cc1nc(CN(C)C(=O)NC(C)Cc2ccsc2)cs1 +Nc1nc(-c2ccccc2Cl)nn1C(=O)C1CC1 +O=C(CN1CCN(C(=O)c2ccncc2F)CC1)N1CCCCCC1 +CCCC(=O)Nc1cccc(CNC(=O)NCc2cnc(C)s2)c1 +O=C(c1scnc1C1CC1)N1CCCC(Cn2ccnn2)C1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCN(c2ccccc2)CC1 +Cc1ccc(CN(C(=O)c2cn3cccnc3n2)C2CC2)cc1C +O=C1COc2cc(C(=O)NCc3ccccc3F)ccc2N1 +COc1cc(F)c(NC(=O)Cc2ccc[nH]2)cc1OC +COCCNC(=O)NCc1ccn(-c2ccc(OC)cc2)n1 +CCCC(=O)N1CCC(C(=O)Nc2nnc(C)s2)CC1 +COC(=O)c1ccc(NC(=O)CCc2csc(C)n2)cc1 +CC(=O)c1ccc(NC(=O)c2cnn(-c3ccncc3)c2C)cc1C +CC(C)NS(=O)(=O)c1ccc(NC(=O)NC(C)(C)C)cc1 +CC(NC(=O)c1ccc(C(C)(C)C)cc1)c1nnc2n1CCC2 +Cc1ncc(CNC(=O)CCCNC(=O)C(C)(C)C)s1 +CN(C)S(=O)(=O)c1ccc(CCc2nc(N)cc(=O)[nH]2)cc1 +Cc1nn(CCC(=O)NCCc2ccccc2)c2ccccc12 +COC(=O)CCCn1c(C(C)C)nc2cc(F)ccc21 +Cc1cccc(C(=O)N(C)Cc2ccccc2F)c1C +O=C(CNc1ccc(Cl)cc1C(F)(F)F)NC1CC1 +Cc1occc1CNc1ncccc1S(N)(=O)=O +Cc1ccc(CCCC(=O)N2CCC(=O)CC2)cc1 +O=C(NCC1CCCC1)c1cc(-c2ccco2)[nH]n1 +COc1ccc(C)cc1CC(=O)Nc1ccnn1C(C)C +CCC(CC)NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +CCCNC(=O)c1ccc(SCc2cscn2)cc1 +CC(CO)NC(=O)c1ccn(-c2ccccc2F)n1 +O=C(CCn1ccccc1=O)Nc1cccc(Oc2ccccc2)c1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)Nc1ccccc1Cl +OCc1nc(-c2ccc(C(F)(F)F)cc2)sc1CO +Cc1cccc(C(=O)NC2CCCCC2C(F)(F)F)n1 +C=CCN(CC=C)C(=O)C1CCN(C(=O)CCC)CC1 +O=C(NCCO)Nc1ccccc1CN1CCc2ccccc21 +COc1ccc(NC(=O)c2cc(C)sc2C)cc1N1CCCC1=O +CC(C)N(CCSc1ccccc1)C(=O)C1=NC(=O)N=C1 +CN(Cc1ccc(C#N)cc1)Cc1cc(Cl)ccc1OCC#N +Cc1cc(N2CCC3(CC2)OCCO3)c2nncn2n1 +C=CCNC(=O)Nc1ccc(CC(=O)NC2CC2)cc1 +COc1cccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)c1OC +CC(CC(O)c1ccccc1)NC(=O)CCc1ccsc1 +CCOC(=O)N1CCN(CCc2cccc(N)c2)CC1 +CNC(=O)c1nc(C(C)(C)NC(=O)c2ccoc2)nc2c1OCO2 +CC1CN(CC(=O)N2CCNC(=O)C2)CC(c2ccccc2)O1 +Cn1cc(Cl)cc1C(=O)OCc1csc(-c2ccccn2)n1 +CCc1ccccc1CNC(=O)N1CC(C)OC(C)C1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3ccc4c(c3)OCO4)c2)n1 +NC(=O)c1cnn(-c2cnc3ccccc3n2)c1N +Cc1ccc(CNC(=O)N2CCN(c3ccccc3O)CC2)s1 +CC(C)Oc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1 +Cc1cc(C)n2ncc(C(=O)N(C3CC3)C(C)C(C)C)c2n1 +c1cncc(CSc2nnc(NCc3ccco3)s2)c1 +CC(=O)N1CCN(CC(=O)Nc2ccc3c(c2)OCCCO3)CC1 +Cc1ccc2c(c1)C(NC(=O)CCCC(=O)N(C)C)C(C)C2 +CC(=O)N1CCN(C(=O)CNC(=O)c2ccc(C)c(C)c2)CC1 +O=C(NC1CCCC1)c1cccc(OCC(F)F)n1 +CCNC(=O)C1CC(NC(=O)c2ccnn2CC)CN1CC=C(C)C +OC(CN1CCc2sccc2C1)c1cccc(F)c1 +O=C(Nc1ccncc1)Nc1ccn(Cc2cccc3cccnc23)n1 +Cc1ccn(-c2ccccc2NCc2ccc(-n3cncn3)cc2)n1 +O=C(CN1CCN(c2ccc(Cl)cc2)CC1)NCC1CC1 +Cc1nn(C)c(C)c1NC(=O)c1ccc2c(c1)CCCC2 +CCc1cnc(NCC2Cn3nnc(-c4cnn(C)c4)c3CO2)nc1 +CC(C)c1nnc2n1CCN(C(=O)Cc1csc(C(C)(C)C)n1)C2 +Cc1ccc(S(=O)(=O)CCCn2nc(C)ccc2=O)cc1 +CCCCCN1C(=O)COc2c(OCC)cc(CO)cc21 +CCCNC1=NS(=O)(=O)c2cc(Br)ccc2N1 +Cc1nc(C)c(C(=O)N2CCCC(C(N)=O)C2)s1 +Cc1cc(C)n(-c2ccccc2NC(=O)CCCC(=O)N(C)C)n1 +CN(C(=O)Cn1nc(C2CC2)n(-c2ccccc2)c1=O)c1ccccc1 +O=C(NC(c1ccc(Cl)cc1)C1CC1)c1cnccn1 +Cn1c(=O)c(SCC(=O)NC2CCCCCC2)nc2ccccc21 +Cc1cc(N2CCc3[nH]nc(C(C)C)c3C2)nc(-c2cccnc2)n1 +COc1ccc2oc(CN3CCOCC3c3ccc(C)o3)cc2c1 +CCCCCNC(=O)c1ccc2c(c1)NC(=O)CS2 +COc1ccccc1CCNC(=O)c1cc2c(OC)cccc2n1C +Cn1nc(C(=O)NCC(C)(C)CCCc2ccccc2)ccc1=O +Cc1cccc(CNS(=O)(=O)c2ccc(OC(C)C)c(C)c2)n1 +Cc1[nH]c2cc(C3CCCN(C(=O)C(C)C)C3)nn2c(=O)c1C +Cn1ccnc1SCCC(=O)Nc1cccc(N)c1 +Cc1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)c(Cl)c1 +CC(C)(C)c1nnc(NC(=O)N2CCc3ccc(O)cc3C2)s1 +O=C(c1cc(F)c(Cl)cc1Cl)N1CCC(CO)CC1 +CCN(CC)C(=O)CSc1nnc(-c2ccc(OC)cc2)n1N +COC=C(C(O)c1ccc(F)cc1)n1nnc2ccccc21 +CCC(=O)Nc1cc(C)ccc1OCc1cc(=O)n2oc(C)cc2n1 +O=C(CCc1ccco1)NCc1nc(-c2cccs2)no1 +COc1ccc(NC(=O)c2sc3nc4c(cc3c2N)CCC4)cc1 +CCCNC(=O)c1cccc(NC(=O)NCc2ccnc(OC)c2)c1 +Cc1cc(NC(=O)CNc2cccc(Cl)c2C)n(C)n1 +O=C(c1scnc1C1CC1)N1CCCC1CC(O)c1cccs1 +COCCn1c(SC)nc2cc(Cl)ccc2c1=O +Cc1nc(C)n(CC(O)c2c(F)cccc2F)n1 +CCn1nc(C)cc(-c2nnc(NC)s2)c1=O +OCc1ccc(CCOc2ccc(F)cc2F)cc1 +Cc1csc2nc(-c3cccc(NC(=O)C4CC4)c3)cn12 +CNc1snc(C)c1C(=O)NCCOc1cccc2ccccc12 +CCCC1CN(S(=O)(=O)N(C)C)CC1Nc1nc(C)ncc1C +O=C(Nc1ccc(OC(F)(F)F)cc1)c1cc(C2CC2)on1 +CCOC(=O)c1cnn2c(C(F)(F)F)cc(C)nc12 +COc1ccc2c(c1)CN(C(=O)NCc1cccc3cccnc13)CC2 +CN(C)C(=O)CSc1nnc2n1C(C)(C)Cc1ccccc1-2 +COC(=O)c1ccc(N2CCOC(c3ccc(F)cc3)C2)nn1 +O=C(CCNc1ncccn1)NCC1CC=CCC1 +C=CCNC(=O)CC1Oc2ccc(C)cc2NC1=O +NC(=O)c1ccc(N2CCC(c3ccc4c(c3)OCO4)C(O)C2)nc1 +CC(O)(CNC(=O)Nc1cccc(-n2cccn2)c1)c1ccsc1 +CSc1nc(C(=O)Nc2ccc(C)cn2)c2ccccn12 +Cc1nc2ncnn2c2ccn(CCC3CCC(O)CC3)c(=O)c12 +CN(CCC#N)C(=O)Cc1cccc2ccccc12 +CCC(C)NC(=O)C1CCN(c2ccc(-c3cccs3)nn2)CC1 +CC(C)NC(=O)N1CCCC2(COCCN(c3nncs3)C2)C1 +COCCNC(=O)c1cnn2c(-c3ccc(C)c(C)c3)ccnc12 +CC(=O)Nc1cc(NCc2ccc(C#N)cc2)ccc1F +CCC(C)NC(=O)Cn1nnc2c(C)n(C)nc2c1=O +CCOc1ccccc1CN(C)C(=O)NCc1ccco1 +Cc1csc2nc(CNc3ccccc3C(C)C)cc(=O)n12 +Cc1ccc(C)c(C(N)C(=O)NCCOCCO)c1 +CCC(C)C(=O)Nc1ccc(C(=O)Nc2nc(C)cs2)cc1 +CCCc1nnsc1C(=O)NCCC(O)c1cccs1 +Cc1cc(C)c(CN2CCCC(c3nnc4n3CCC4)C2)cc1C +Cc1cccc(OCC(=O)NCC2CCN(c3ncccn3)CC2)c1 +CC(=O)NC(C)(C)c1noc(-c2ccc(Br)cc2)n1 +Cc1cnc(C(=O)Nc2ccc3c(c2)nc(C(C)(C)C)n3C)cn1 +Cn1ncnc1SCC(=O)NCc1ccccc1 +CCCCc1nnc(SCc2ccccc2)n1N +CC(=O)c1ccc(NC(=O)Nc2ccc3c(c2)oc(=O)n3C)cc1 +Cc1cccc(CN(C(=O)c2ccc(-n3ccnc3)nc2)C2CC2)c1 +CN(C(=O)CSc1nc2ncccn2n1)c1nccs1 +COC(CNC(=O)c1ccccc1C)c1cccc(F)c1 +COCCCNC(=O)c1c(C)c(N)c(C)[nH]c1=O +CN(C)C(=O)C1CC2OCCC2N(Cc2ccc3ccccc3n2)C1 +CN(CC(=O)N=c1sccn1C)c1ccccc1 +O=C(NCCNC(=O)c1cnccn1)c1cccc(Cl)c1 +COc1ccc2cc(C(=O)Nc3cccc(-n4cnnn4)c3)ccc2c1 +COc1cc(C)c(S(=O)(=O)NCCCO)c(C)c1 +CC(Sc1nnnn1C)C(=O)Nc1ccccc1F +CCOC(=O)NCC1(c2ccccc2)CCOCC1 +O=C(CCc1c(-c2ccc(F)cc2)[nH]c2ccc(F)cc12)N1CCC1 +Cc1cccc(OCCNS(=O)(=O)c2cccnc2)c1 +Cc1cccc(C(=O)OCC(=O)Nc2c(C)cccc2C)c1N +O=C(c1ccn(C(F)F)n1)N1CCC(Cc2ccc(F)cc2)CC1 +Cc1cc(NC(=O)c2cc(F)cc3[nH]cnc23)n(C)n1 +CC(C)CCNC(=O)CN(C)c1ncnc2nc[nH]c12 +CCOC(=O)c1sc(NC(=O)c2ccc(CC)o2)nc1C +CC(=O)c1cc(Cl)c2oc(-c3ccc(N)cc3)nc2c1 +Cc1nn(-c2ccccc2)cc1CNc1ccccc1 +CC(NC(=O)CCC1Cc2ccccc2NC1=O)c1ccc(F)cc1 +COCCCN1C(=O)CCC2CN(C(=O)Cn3cncn3)CCC21 +CCNC(=O)c1cc(-c2cccnc2)nc2ccccc12 +Cc1nc(N)nc(COc2ccc(C(C)(C)C)cc2)c1C(N)=O +Cc1nc(COc2ccc(Cl)cc2)[nH]c(=O)c1CCO +Cc1cc(F)cc(NC(=O)Cc2cccc(OCC#N)c2)c1 +N#Cc1cccc(Cn2ccnc2-c2ccccn2)c1 +COc1cc(OC)cc(C(=O)NCCc2ccccc2)c1 +CSc1nccc(N2CCC(CNC(=O)OC(C)(C)C)C2)n1 +NC(=O)c1ccc(CNC(=O)c2ccc(-c3cscn3)cc2)o1 +Cc1ccc(CNC(=O)C23CC4CC(CC(O)(C4)C2)C3)cc1F +CCOc1ccccc1NC(=O)CSc1nnc2ccccn12 +O=C(NCc1cccs1)c1cc2n(n1)CCCC2 +CN(C(=O)CSc1ncccc1Cl)C1(C#N)CCCCC1 +COc1cccc(-c2nc(N3CCCCC3)nc3nn(C)c(N)c23)c1 +CCOc1ccc(NC(=O)NCc2cc(Cl)ccn2)cc1 +Cc1ccnc(NC(=O)c2cc(S(=O)(=O)N3CCCC3)cn2C)c1 +COc1ccc(CCC(=O)Oc2ccccc2OC)cc1 +CCCn1c(C2CC(=O)N(Cc3ccccc3)C2)nc2ccccc21 +O=C(Cn1cccc1)Nc1ccc(Cl)cc1F +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccc(F)cc1 +Cc1cc(=O)oc2cc(OCC(=O)Nc3ccc(O)cc3)ccc12 +COCCN(C)C(=O)Nc1ccn(-c2ccccc2)n1 +CC(C)NC(=O)c1ccc(NC(=O)C2CCCC2)cc1 +Cc1nc(CC(=O)N2CCC(c3nnc4ccccn34)CC2)cs1 +CC(C)Oc1ccccc1NCC(=O)N1CCc2sccc2C1 +CC(C)N(C)C(=O)COc1ccc2ccccc2c1 +NC(=O)c1ccc(-c2ccc(Cl)c(Cl)c2)o1 +COC(=O)c1cccc(CSc2nc(C3CC3)nc(C)c2C#N)c1 +COc1ccccc1NC(=O)N1CCC(c2n[nH]c(C3CC3)n2)CC1 +Cc1nn(C)c(C)c1CCNS(=O)(=O)c1ccc2c(c1)CCCC2 +Cc1nc(C(F)(F)F)nc(-c2cccnc2)c1C +COc1cccc2cc(C(=O)NCCN3CCOCC3)c(=O)oc12 +CCCC1CN(C(=O)c2cc(C)n(-c3ccc(F)cc3F)n2)CCO1 +CCn1ncc(NC(=O)c2cc(C3CC3)nc3c2cnn3C)c1C +Cc1nn(C)c(C)c1CNC(=O)CN1CCSc2ccccc21 +O=C(Nc1ccncc1)C1COCC(=O)N1Cc1ccccc1 +Cc1cc(C(=O)COc2ccccc2)c(C)n1-c1nccs1 +COc1ccc(C)cc1NC(=O)Nc1c[nH]c(=O)[nH]c1=O +Nc1ncccc1-c1nc(-c2ccc(C(F)(F)F)cc2)no1 +N#Cc1ccc(C(=O)N(Cc2ccc(C(F)(F)F)cc2)C2CC2)cc1 +CC1(CO)CCCC1NS(=O)(=O)N1CCCCCC1 +O=C(c1cccc(-n2cnnn2)c1)N1CCCCCC1c1ccccc1 +Nc1ccc(C(=O)Nc2ccccc2N2CCOCC2)cc1 +CC(=O)N1CCN(C(=O)c2cccs2)C(C(=O)NCC(N)=O)C1 +CN(C)c1ccccc1NC(=O)N1CCCC(O)C1 +CNc1ccc(C(=O)Nc2cc(Br)ccc2C)cn1 +CS(=O)(=O)c1ccc(C(O)Cn2cc(N)cn2)cc1 +Cc1nn(C)cc1S(=O)(=O)N(Cc1ccccc1)c1ccccc1 +O=C1COc2cc(S(=O)(=O)NC3CCCCC3)c(Cl)cc2N1 +Cc1ccc(C(=O)N2CCC(C)CC2)c(F)c1F +COc1ccc(COC(=O)c2oc(C)nc2C)cn1 +O=C(Nc1cnc2ccccc2c1)c1cccc2[nH]ccc12 +CC(C)(C)CCNC(=O)Cc1ccc(S(N)(=O)=O)s1 +CCC(=O)N1CCCc2c(cnn2-c2ccc(OC)cc2)C1 +NC(=O)c1ccc(Cl)cc1NC(=O)c1cccc(C(F)(F)F)c1 +Cc1ccc2[nH]c(C3CCCCN3C(=O)Cn3cnnn3)nc2c1 +Cn1ncc(C(=O)Nc2cc(Cl)ccc2O)c1N +Cc1ccc2oc(=O)n(CC(=O)Nc3nc(C)n(C)n3)c2c1 +COC1CCN(c2nc3nonc3nc2NCc2ccccc2)CC1 +COc1ccc(Nc2nc3ccccc3n3cnnc23)cc1OC +CCOc1ccccc1C(=O)Nc1cccn2c(C)nnc12 +NC(Cc1ccccc1)C(=O)N(Cc1ccccc1)c1ccccc1 +Fc1cc(F)c2c(c1)C(c1nccs1)NCC2 +CNc1nc2c(s1)C(c1cccs1)CC(=O)N2 +O=C(c1cnccn1)N1CCOC2(CCCN(c3ncccn3)C2)C1 +CCc1nnsc1C(=O)N1CCn2c(CC)nnc2C1 +c1ccc(-c2cc(-c3nn4c(-c5cnccn5)nnc4s3)no2)cc1 +c1ccc(-c2nc(N3CCC(OC4CCOCC4)CC3)no2)cc1 +Cc1cccnc1NC(=O)c1c2c(nc3c1cnn3C(C)C)CCC2 +CCc1sc(C(=O)NCC(C(C)C)N2CCOCC2)cc1C +Cc1nc(-c2cccc(S(=O)(=O)Nc3cccnc3)c2)no1 +CC1CC1CNC(=O)NCCc1nnc2ccccn12 +CC1(C)COc2ccc(NS(C)(=O)=O)cc2NC1=O +O=C(c1cc(F)cc(F)c1)N1CC=C(c2c[nH]c3ccccc23)CC1 +CCOCC1CCCN(C(=O)NCc2cscn2)C1 +CC(C(=O)N(C)C)N1CCN(c2nc3ccccc3s2)CC1 +CC(=O)N1CCOCC1C(=O)NC(C)Cc1ccc2ccccc2c1 +COc1ccc(NC(=O)c2cn3cccnc3n2)c(OC)c1 +COc1cc(CNS(=O)(=O)c2c(C)cc(C)cc2C)ccn1 +O=C(NCc1ncc[nH]1)Nc1ccc(Oc2ccc(F)cc2F)nc1 +O=C(Nc1cccnc1)C1CC1c1ccc(OC(F)(F)F)cc1 +Cc1nc(NCCNC(=O)C2CCCC2)cc(N(C)C)n1 +COC(CNC(=O)CCc1ccccc1)c1cccc(F)c1 +CC(NCC1CCCO1)C(=O)c1ccc2c(c1)NCCO2 +COc1ccccc1CNC(=O)c1cnc(N(C)C)nc1 +Cc1ccc(C(=O)N(C)C)cc1Oc1ccncc1 +CCN(C(=O)c1cccc(OC)c1F)c1ccncc1 +C#CCN(CC(=O)Nc1cc(C)no1)C1CCc2ccccc21 +O=C(NCCc1ccccc1)c1cc(N2CCCC2=O)ccc1Cl +CCC(C)n1ncc(C(=O)Oc2ccc(C#N)cc2)c1C1CC1 +CC(C)N(C)c1ccc(NC(=O)NCc2ccccn2)cc1F +O=C(Nc1ccc(-n2cccn2)c(F)c1)c1cn[nH]n1 +Cc1ccccc1NC(=O)c1ccc2c(c1)S(=O)(=O)N(C)C2=O +CCCC(C)NC(=O)C1CCCN(C(=O)Cc2ccccc2OC)C1 +Cc1cc(NC(=O)C2CCCOC2)ncc1Br +CN(C)C(C(=O)Nc1ccc(CC(N)=O)cc1)c1c(F)cccc1F +Cc1ccc(-c2n[nH]c(CNC(=O)NCc3ccccc3)n2)cc1 +CC(=O)c1ccc(NC(=O)N2CCN(c3nccs3)CC2)cc1 +COc1cc(NC(=O)c2ccc3oc(=O)n(C)c3c2)cc(OC)c1 +N#Cc1ccc(OCC(=O)Nc2cccc(C(F)(F)F)c2)cc1 +COc1ccc(OC)c(NC(=O)C2CSc3nccc(=O)n3C2)c1 +CCOC(C)C(=O)Nc1nc(C(C)(C)C)cs1 +COC(=O)c1c(Br)c2ccccc2n1CC#N +CC(C)(C)C(=O)NCCc1csc2ncnn12 +N#CC1(C(=O)NCc2ccc(COCC(F)(F)F)cc2)CCCC1 +CC(=O)NC1CCCN(C(=O)c2cc(Cl)cc3cccnc23)C1 +COC(=O)CCC(=O)Oc1ccc(C)cc1OC +CCCNC(=O)c1cc(-c2cccc(OC)c2)on1 +Cn1nc(C(=O)NC2CC(=O)N(C3CC3)C2)ccc1=O +COC(=O)Nc1ccccc1C(=O)NCc1nc2ccccc2n1C +Cc1c[nH]nc1C1CCN(S(=O)(=O)c2ccc(F)cc2)C1 +CCOC(=O)C1CCCN1C(=O)c1cnoc1C +Cc1cc(C)n(CC(=O)NC2CCN(S(C)(=O)=O)CC2)n1 +Cc1cc(C2CCCN2C(=O)Nc2ccccc2C)no1 +CN(C)C(=O)c1cc(NC(=O)N(CCO)Cc2ccccc2)ccn1 +O=S(=O)(Nc1ccccc1)c1cccc2cccnc12 +CC(C)(C)NC(=O)CSc1nnnn1C(C)(C)C +O=C(Cc1nc(CO)cs1)Nc1cc(Cl)cc(Cl)c1 +Cc1nc(COC(=O)c2c[nH]nc2-c2c(F)cccc2F)no1 +CC(=O)Nc1ccsc1C(=O)Nc1cnc2n1CCCC2 +CC1CCC(CO)(NS(=O)(=O)CC2CCCO2)CC1 +CC1CCCCC1NC(=O)CN1CCN(C(=O)C2CCCO2)CC1 +CC(=O)N1CCC(C(=O)OC2CCCCC2)CC1 +CCC(C)C(=O)COc1nc(Cc2ccc(F)cc2)no1 +O=C(Nc1ccccc1OC(F)F)c1cnn(-c2ccccc2)n1 +CC(C)NC(=O)c1cc2cnn(C(C)C(C)(C)C)c2nc1N +CC(=O)NCCNC(=O)NCc1cccc(C#N)c1 +CC(C)n1cnnc1SCCOc1cccc(Cl)c1 +COc1cccc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)c1 +Cn1cc(CCNC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)cn1 +COc1cc(C(=O)NC(C)C2CCCO2)cc2c1OCCO2 +CN(C(=O)c1cnn(Cc2ccccc2)c1)c1ccccc1 +COC(=O)Cn1cc(NC(=O)CCn2ccnn2)cn1 +Cc1cc(-c2ccccc2)nn1-c1nc2ccccc2c(=O)n1O +CCC(c1ccccc1)N(CC(=O)OC)C(=O)c1sccc1C#N +CC(=O)NC(C)(C)c1noc(-c2cc(C)n(C3CCCCC3)c2C)n1 +CC(=O)Nc1ccc(C(=O)N(C)c2nc3ccccc3s2)s1 +CCc1cc(C(=O)N2CCC(c3nn(C)c4ncccc34)CC2)on1 +O=C(Cn1c(=O)oc2ccccc21)Nc1cccc(C(F)(F)F)c1 +Cn1ccc(NC(=O)CCNC(=O)C23CC4CC(CC(C4)C2)C3)n1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NCCCN1CCCC1=O +Cc1ccc(S(=O)(=O)NCCC(=O)NCC2CCCCC2)cc1 +O=C(c1cccnc1)N1CCCN(C(=O)c2ccccc2Cl)CC1 +Cc1ccc(C(=O)N(C)CCN(C)C(=O)OC(C)(C)C)c(=O)[nH]1 +COc1cccc(NCc2nn(CCC(C)C)c(=O)[nH]2)c1 +CCCc1nn2c(CO)c(-c3cccnc3)nc2s1 +Cc1n[nH]c(C(=O)NCCCS(N)(=O)=O)c1Br +CCN(Cc1ccccc1)C(=O)c1cc(C)n(-c2cc(C)on2)c1C +Cc1cccc(CSc2nnc(-c3ccncc3)o2)c1 +Cc1cc(C)cc(OC(=O)Cn2ncc(=O)c3ccccc32)c1 +O=C(NCc1noc(-c2ccccc2)n1)c1cc2ccccc2oc1=O +COc1cc(C)ccc1OCCCSc1nc(N)cc(=O)[nH]1 +CC1CN(C(C)C(=O)N(C)CC(=O)NC2CC2)CC(C)O1 +CCC(C)(O)CNC(=O)Nc1cccc(-c2nnco2)c1 +CC(NC(=O)Nc1cccc(C(=O)NC(C)(C)C)c1)c1ccncc1 +CS(=O)(=O)c1ccc(Oc2ccc(C#N)cn2)cc1 +O=S(=O)(NCCC(F)(F)F)c1ccc(F)cc1 +O=C(CC1(O)C(=O)Nc2cc(Cl)cc(Cl)c21)c1ccncc1 +CC(NC(=O)N(C)Cc1nccn1C(F)F)c1ccc(F)c(F)c1 +O=C(CNC(=O)C1CC(=O)N(c2ccc(F)cc2)C1)NC1CC1 +Cc1cnn(CC(=O)N2CCN(Cc3ccc4c(c3)CCO4)CC2)c1 +CC1CN(C(=O)Cc2ccccc2F)CC(C)O1 +Cc1ccc(C)c(SCC(=O)N(C)C(C)C)c1 +O=C(CC12CC3CC(CC(C3)C1)C2)NCC(=O)Nc1cccnc1 +CNC(=O)c1cccc(NC(=O)C(C)Nc2ccc(F)c(F)c2)c1 +CC(NC(=O)c1ccc2c(c1)CCCC2)c1ccc(-n2cncn2)cc1 +CC(=O)c1ccc(S(=O)(=O)Oc2ccccc2Cl)cc1 +COc1ccc(NC(C)=O)cc1CCC(C)(C)O +CCCn1c(-c2cc(C)ccc2OC)ccc(CO)c1=O +Cc1ccc(S(=O)(=O)NCCNC(=O)OC(C)(C)C)c(C)c1 +Cc1ccc(S(=O)(=O)CC(=O)N2CCCCC2)c(C)c1 +Cc1ccc(C(=O)N2CCC3(CC2)NC(=O)CC3c2ccccc2)cn1 +CC(=O)Nc1cc(S(=O)(=O)Oc2c(C)nn(C)c2C)ccc1F +CC(NC(=O)c1cnc2ccccn12)c1ncon1 +O=C(c1cccc(Cn2cnc3ccccc3c2=O)c1)N1CCCCC1 +NC(=O)COc1cccc(CSc2ccc(Cl)cc2)c1 +CC(NC(=O)c1n[nH]c2ccccc12)C(=O)Nn1cnc2ccccc21 +O=C(NCCC(=O)N1CCCCC1)Nc1c(F)cccc1F +Nc1ccc(Cl)c2c(C(=O)NCCc3ccccc3)nccc12 +CN(C(=O)CN1C(=O)C2=C(CCC2)Nc2ccccc21)c1ccccc1 +Cc1cc2cc(C(=O)N(Cc3ccc4c(c3)OCO4)C3CC3)ccc2o1 +COC(=O)CC(NC(=O)c1ccc(OC)cc1)c1cccs1 +CC(C)=CCN1CC(NC(=O)c2nc(C)c[nH]2)CC1C(=O)NC(C)C +CCn1c(=NC(=O)c2ccn(C)n2)sc2c(OC)ccc(OC)c21 +CC(=O)NCCNC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1 +Nc1cc(CCOc2cccc3ccccc23)nn1CCO +CC(C)n1nccc1NC(=O)NCC(O)COc1ccc(F)cc1 +Cc1noc(C)c1S(=O)(=O)NCCOC1CCCCC1C +Cc1occc1C(=O)Nc1cc(NC(=O)c2cnns2)ccc1F +CCSc1nnc(NC(=O)COc2cc(C)on2)s1 +Cc1cc(C)n2nc(CC(=O)NCCc3ccc(F)cc3C)nc2n1 +CC1CCC(N(C)C(=O)CNc2ccc(C(=O)NC3CC3)cc2)CC1 +Cc1ccc(NC(=O)N2CCN(C(=O)C(C)(C)C)CC2)c(C)c1 +Cc1ccc(CN2CCc3ncnc(C)c3CC2)o1 +CCn1nc(-c2cccc3ccccc23)cc(C(C)=O)c1=O +CC(C)NC(=O)CN(C)C(=O)c1cc2c(s1)CCCC2 +CC1c2ccccc2OC1C(=O)N1CCCC1CC(=O)c1ccccc1 +O=C(CCC(=O)OCC1CCCO1)Nc1ccc(Cl)c(Cl)c1 +O=C(NCCNC(=O)C1CC1)c1ccc(Br)cc1Cl +COc1cccc(C(=O)N2CCN(c3ccc(Cl)cn3)CC2)c1F +CCOC(=O)C1=C(CN2CCCCC2)NC(=O)NC1c1ccco1 +CC(=O)c1c(C)[nH]c(C(=O)CN2CCN(c3nccs3)CC2)c1C +Cc1ccc(OC2CCN(Cc3scnc3C)CC2)cc1C +COCC1C(=O)NCC12CCN(C(=O)Cc1ccccc1)CC2 +CSc1nc2n(n1)C(c1cccc(O)c1)C1C(=O)CCCC1=N2 +COc1cc(OC)c(NC(=O)c2ccnc(F)c2)cc1F +Cc1ccc(C(=O)N(C)c2nc3ccccc3o2)cn1 +COc1ccc(-n2ccn(Cc3ccccc3Cl)c(=O)c2=O)cc1 +O=c1[nH]nc(SCc2ncc(-c3cccc(Cl)c3)o2)n1C1CC1 +Cc1ccc(NC(=O)C2(c3ccccc3)CC2)cc1S(C)(=O)=O +CC(=O)c1cc2c(cc1NC(=O)CSc1ccccc1)OCO2 +Cc1cc(C(=O)Nc2cc(F)ccc2F)c2c(C)noc2n1 +COc1ccc(NC(=O)C(NC(=O)Cc2ccccc2)C(C)C)cn1 +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)Oc1ccc(Cl)cc1 +CC(C)(C)CC(=O)Nc1ccccc1N1CCNC(=O)C1 +Cc1cc(C)n(CCN2CC3(CCOC3)CCC2=O)c(=O)n1 +CC(=O)NCCNC(=O)C1CC(=O)N(C(C)C)C1 +CN1CCC(Sc2nc3c(n2-c2ccccc2)CCCC3)C1=O +COc1ccccc1OCC#CCNC(=O)c1cc(C)on1 +COc1ccc(NS(=O)(=O)c2csc(C(N)=O)c2)cc1Cl +COc1ccc(N(C)C(=O)C2CC2c2ccccc2OC)cc1OC +CCc1noc(Cn2cnc3c([nH]c4ccc(F)cc43)c2=O)n1 +COC(=O)c1cccc(NC(=O)C2CC2c2cccc(F)c2)c1O +CCC(C)NC(=O)CSc1ncc(C#N)c(N)n1 +CCNc1nc(-c2cc(-c3ccncc3)sc2C)cs1 +CN1CCN(C(=O)c2ccc(-c3cnn(C)c3)nc2)CC1 +Cc1ccc(C(=O)NCc2ccco2)cc1N(C)S(C)(=O)=O +Cc1nc2ncnn2c(C)c1CCC(=O)Nc1ccccc1 +COc1ccc(-c2ccc(N)c(=O)n2C(C)C)c(OC)c1 +Cc1ccsc1C(=O)N1CCCCC1CNC(=O)OC(C)(C)C +Cc1ccc(C2CCCN(c3cc(C)ncn3)C2)nc1 +Cc1cccc(C(=O)Nc2cnn(-c3ccccc3F)c2)c1 +COc1ccc(C(C)NC(=O)NC(C)C(C)CO)c(OC)c1 +COCCN1CCN(C(=O)c2ccc(F)c(F)c2F)CC1=O +CCOCCNC(=O)N1CCN(CC(=O)NC(C)C)CC1 +Cc1noc(C)c1CCC(=O)N1CCOC(C)(C)C1 +COc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c(F)c1 +O=C(COc1ccccc1Cl)N1CCN(c2ccccc2O)CC1 +COCCN1CC(C(=O)N(C)Cc2cccc(C#N)c2)CC1=O +Cn1c2ccccc2n2nc(-c3cccc(N)c3)nc12 +Cc1ccc(N2CC(C(=O)NCc3n[nH]c(=O)[nH]3)CCC2=O)cc1C +Cc1occc1C(=O)n1nc(C(F)(F)F)cc1C +CCCN(C)C(=O)C(C1CCCC1)N1CCN(C(=O)C2CCC2)CC1 +OCC1COCCN(Cc2cnc(C3CCCCC3)nc2)C1 +CS(=O)(=O)c1ccsc1NC(=O)c1scnc1C1CC1 +CC(C)CC1COCCN1CC(=O)NCc1ccccc1F +COc1ccc(C(O)C(C)NC(=O)c2ccc(S(C)=O)cc2)cc1 +O=C1CCN(C(=O)c2cccnc2OCC(F)(F)F)CCN1 +Cc1cccc(OCCCC(=O)Nc2ccc3c(c2)COC3)c1 +COc1ccccc1S(=O)(=O)CC(=O)NC1CCCCNC1=O +CC(=O)N1CCc2ccc(NC(=O)COc3ccc(Cl)cc3)cc21 +CCCNC(=O)Cn1nnc(CO)c1-c1ccccc1 +CC(C)CNC(=O)C1(NC(=O)c2scnc2C2CC2)CCCC1 +Cc1cc(Br)ccc1NC(=O)N(C)Cc1ccncc1 +COc1ccc(S(=O)(=O)Nc2c(O)cccc2F)cc1OC +COc1cccc2c1cc(C(=O)NCCc1ccccc1)n2C +COc1ccccc1N1CCCC(NC(=O)NCc2ncn(C)n2)C1 +O=C(CCn1ccnc1)Nc1nc2ccccc2s1 +CN1C(=O)CN2CCc3ccccc3C2c2cc(Cl)ccc21 +COc1ccccc1NC(=O)c1ccc2nccnc2c1 +CC(C)(NC(=O)Cc1ccc[nH]1)c1cccc(F)c1 +COCc1nc(-c2cccc(OC)c2)sc1CO +CCCCN(CC)C(=O)Cn1nc(-c2cccs2)oc1=O +COC(=O)C1CC(O)CN1Cc1nc2sc(C)c(C)c2c(=O)[nH]1 +COc1ccccc1NC(=O)COC(=O)c1ccc(SC)cc1 +O=C(COc1ccc(F)cc1)Oc1cccc2cccnc12 +CCNC(=O)c1snc(-c2ccc(OC)cc2)c1N +Cc1ccc(OCCN(C)C(=O)C2CCC(=O)N2)cc1 +CC(C)C(NC(=O)C1CC(=O)N(C)C1)c1ccc2c(c1)OCCO2 +Cc1ccc(-n2ncc(C(=O)N3CCOCC3)c2N)nn1 +CCCCN(C)C(=O)CN1C(=O)CSc2ccccc21 +Cc1ccccc1N1CC(C)N(C(=O)Cc2ccccc2)CC1=O +O=C(OC1CCCc2ccccc21)C1CC(=O)N(CC(F)(F)F)C1 +Cc1cc(C)c(C(=O)N2CCC(NS(C)(=O)=O)C2)c(C)c1 +Cc1cc(Br)cn(CC(O)COC(C)C)c1=O +COc1ccc(N2CCCCS2(=O)=O)cc1Cl +CCOc1ccc(C2OC(=O)Cc3cc(OC)c(OC)cc32)cc1 +NC(=O)c1cccc(COC(=O)c2cnc(C3CCCO3)s2)c1 +CCC(C)C(=O)Oc1ccc(NC(=O)OC)cc1 +Cc1cc(C)nc(-n2nc(C)cc2NC(=O)Cc2cccc(F)c2)n1 +CC(C)(O)CCc1cccc(C(=O)NC2(C(N)=O)CCCC2)c1 +CC(=O)Nc1cccc(C(=O)Nc2ccccc2N2CCCCC2)c1 +CCC(=O)N1CCCn2nc(-c3ccncc3)cc2C1 +COc1ccccc1Cc1nc2cc(C)ccn2n1 +O=C(NCc1nnnn1-c1ccccc1)c1ccccc1C(F)(F)F +CC1(C)OCC2OC=CC(OCc3ccccc3)C2O1 +CC(C)(C)c1ccc2c(c1)C(c1nc[nH]n1)NCC2 +Cc1cccc(OCCC(=O)NC(C)C(=O)NC(C)(C)C)c1C +NC(=O)c1n[nH]c2ccc(NCc3ccncc3)cc12 +O=C(c1ccc(Cn2cccn2)cc1)N1CCc2cc(F)ccc2C1 +O=C(COc1ccc(Br)cc1)n1ccnc1 +Cc1cc(C)c(NC(=O)CN(C)c2ncnc3c2cnn3C)c(C)c1 +Cc1occc1C(=O)Nc1ccc(Cc2nnc3ccccn23)cc1 +Cc1ccccc1C(=O)NC(C(=O)NCCC(C)C)C(C)C +COC(=O)N1CCC(NC(=O)c2ccc(C(C)C)cc2)CC1 +CCOC(=O)c1cccc(N(CC)Cc2c(C)noc2C)c1 +OCc1ccc(-c2nccn2CCOc2ccccc2Cl)o1 +Cc1noc(CCCC(=O)NCc2ccc3[nH]c(=O)[nH]c3c2)n1 +O=C(CCn1ncc2c(Cl)cccc21)N1CCCC1 +COc1ccccc1NC(=O)Cn1cnc(SC)c(C#N)c1=O +CC(C)(C)NC(=O)CCC(=O)c1cc(F)ccc1F +OCc1c(-c2cccnc2)nc2cc(Cl)ccn12 +N#Cc1c(F)cccc1NC(=O)c1cccc(OC(F)F)c1 +Cc1c(C(=O)N2CC(=O)N(C)c3ccccc32)cnn1-c1ccncc1 +CCOC(=O)Nc1cccc(S(=O)(=O)N2CCOCC2)c1 +CCCNC(=O)CCC(O)c1cccc(OC)c1 +O=C(Nc1ccccc1)Nc1nc(CC(=O)N2CCOCC2)cs1 +CCN(Cc1ccc2c(c1)OCO2)S(=O)(=O)c1ccc(C)cc1 +CNC(=O)c1ccc(S(=O)(=O)NCC2CCCO2)cc1 +COc1ccc(-n2c(C(C)OC(C)C)n[nH]c2=O)c(C)c1 +COC1CCN(C(=O)NCc2ccc(SC)cc2)CC1 +COC(=O)c1ccc2nc(NC(=O)c3cccnc3)sc2c1 +O=C1CC2CCC(CN1)N2C(=O)Cc1ccc(O)c(F)c1 +COc1cccc2cc(C(=O)Nc3onc4c3CCCC4)oc12 +Cc1nc(CC(=O)N2CCCN(c3cccnn3)CC2)cs1 +NC(=O)C1CCCN(C(=O)COc2ccc(-c3nnco3)cc2)C1 +Cc1ccc2nc(C)c(C(=O)N(C)CC3CC3)cc2c1 +CCc1ccc(S(=O)(=O)Nc2ccc(OC)c(OC)c2)cc1 +CCc1ccccc1NC(=O)COC(=O)c1cccc(NC(C)=O)c1 +CCc1onc(C)c1NC(=O)N1CCCCC1CN1CCOCC1 +CCCCCCc1nc(-c2ccc(C#N)cn2)no1 +CCOc1ccc(-c2nc(CC)n[nH]2)cc1OCC +COc1cccc(NC(=O)N(C)Cc2csc(C)n2)c1 +O=C(C1COc2ccccc2O1)N1CCCC1c1ccc[nH]1 +Cc1sc(=O)n(CC(=O)NCc2cccc(Cl)c2)c1C +Cc1noc(C)c1CNC(C(=O)N1CCC(C)CC1)c1ccccc1 +C=CCCOC(C)C(=O)N(C)c1ccccc1S(C)(=O)=O +CN(c1ccccc1C(N)=O)S(=O)(=O)c1cc(F)ccc1F +O=C(c1cccc2ccnn12)N1CC2C3CCC(O3)C2C1 +COc1ccccc1CNC(=O)C(C)Nc1cccc(C(C)=O)c1 +Cc1ccc(CC(=O)NCC2COc3ccccc3O2)cc1C +Cc1cc(C)n(CCNC(=O)CCS(=O)(=O)c2ccccc2)n1 +Cc1ccc(NC(=O)C(C)n2c(=O)oc3ccccc32)cc1Cl +COCC(=O)N1CCc2c(-c3ccccc3)cccc2C1C +COC(=O)c1cccc(NC(=O)COC(=O)c2ccco2)c1 +CNC(=O)NCC(=O)N1CCCC1c1ccc(C)s1 +CCc1cccc(OCCc2nc(C#N)cs2)c1 +CCOc1cccc(OCc2nc(C)c(C(C)=O)s2)c1 +CC1CN(CC(=O)Nc2ccc(CN3CCOCC3)cc2)CCO1 +CCCOCC(=O)NCC(O)c1ccc2ccccc2c1 +CS(=O)(=O)NCc1nnc2n1CCN(Cc1ccncc1)C2 +CC1CC1C(=O)Nc1cccc(C(=O)C(C#N)c2ccccn2)c1 +CC(=O)NCCCc1nc(C2CCCCC2)no1 +CCSc1cc(C(=O)NCc2ccccn2)ccn1 +O=C(CNC(=O)c1ccc2c(c1)CCC2)Nc1ccc2nccnc2c1 +c1ccc2oc(C3CCCN(Cc4nnc(C5CC5)o4)C3)nc2c1 +c1cc(OCC2CCCO2)ccc1CNc1ccc2c(c1)COC2 +CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)Nc1c(Cl)cccc12 +COCC(NC(=O)c1cc(Cl)ccc1OC)C(N)=O +CCn1nnnc1SCc1ccc(Cl)cc1Cl +C=CCC1(CO)CCCN(S(=O)(=O)N2CCC(OC)CC2)C1 +CCOC(=O)C1CCN(C(=O)CN2CCCn3nc(C)cc32)CC1 +COc1cc(F)c(NC(=O)c2cnc3ccc(C)cn23)cc1F +O=C(c1sccc1-n1cnnn1)N1CCc2ccccc21 +CC(NC(=O)N1CCN(c2ncccn2)CC1)c1ccccc1Cl +CC(C)N(CCc1nccs1)C(=O)c1c[nH]c2c(cnn2C)c1=O +Cc1cccc(C(=O)N(CC2CCOC2)C2CC2)c1C +N#CCC(=O)Nc1ccc(Cl)cc1Br +Cc1nn(-c2ccccc2)c2c1S(=O)(=O)c1ccccc1-2 +CCNC(=O)Cn1c(CO)cnc1SCc1cccc(F)c1 +C=CCn1nnc(NC(=O)c2ccc(C)c(Cl)c2)n1 +CC(Cn1cccn1)NC(=O)N(CC1CCCO1)CC1CCCO1 +COc1ccccc1COC(=O)c1ccc(Cn2cncn2)cc1 +Cc1ccc(Cl)cc1C(N)C(=O)NCC(C)C +FC(F)(F)c1cccc(CNc2cccnn2)c1 +O=C(NC1CCCC1)c1ccc(NC(=O)c2ccco2)cc1 +NC(=O)CCCN1C(=O)CNc2cc3c(cc21)CCCC3 +Cc1nnc(CSc2nnc(-c3ccccc3F)n2C2CC2)o1 +CCn1ccnc1SCC(=O)Nc1ccc(C)c(F)c1 +O=C1CC(c2ccccc2)Cc2c1cnc1nc(C(F)(F)F)nn21 +CC(=O)c1cccc(NCC(=O)Nc2ccc(C#N)cc2)c1 +CC(C)COc1ccc(C(=O)N2CCN(c3cnccn3)CC2)cn1 +CC(=O)c1c(C)nc(C)nc1SCc1cc(F)cc2cccnc12 +COc1ccc(NC(=O)c2cccs2)cc1N1CCCC1=O +N#CC(NCCO)c1cc(Cl)c2c(c1)OCO2 +C=CCn1c(C)nnc1SCC(=O)Nc1c(C)cccc1C +CC(C)C(=O)NCC1CCCN(C(=O)c2ccc(Cl)cc2)C1 +CCC1CN(C(=O)c2c(C)noc2C)CC1N1CCOCC1 +COC(=O)c1cnc(C=Cc2cnc(C(C)(C)C)s2)s1 +Cc1ccc(S(=O)(=O)NC(=O)NC(C)(C)c2ccncc2)cc1 +CCc1cnc(CCNC(=O)N2CCCC(C(=O)NC)C2)s1 +CCNS(=O)(=O)c1ccc(F)c(C(=O)N2CCCC(O)C2)c1 +CCn1ncnc1C1CC(=O)Nc2cc3[nH]ncc3cc21 +Cc1ccc(N(C)C(=O)c2cccc(-n3cnnn3)c2)cc1 +CCOC(=O)C1C(c2ccccn2)NC(=O)NC1(O)C(F)(F)F +CC(C)c1ccc(S(=O)(=O)N(CCC#N)CC(F)(F)F)cc1 +CC(C)C(C)NC(=O)NCc1nc(-c2cccs2)no1 +COc1ccccc1C(=O)NC(C(=O)NCc1n[nH]c(C)n1)C(C)C +CC(=O)Nc1ccc(NCc2csc(C)n2)c(Cl)c1 +CN(CCC#N)CC(=O)N1CCC(Cc2ccccc2)CC1 +CCCNc1nnc(SCC2CCCCO2)s1 +CNC(=O)NCC(=O)Nc1ccccc1OCCc1ccccc1 +O=C(c1ccc(-c2cnc(Oc3ccccc3)nc2)cc1)N1CCCC1 +CC(Nc1nc(C2CC2)nc2sc3c(c12)CCCC3)C(=O)N(C)C +Cc1cc(C(=O)NCCOc2ccccc2)c2c(=O)[nH]n(C)c2n1 +O=C(Cc1c(F)cccc1F)Nc1ccc(-n2cncn2)cc1 +Cc1ccc(O)c(C(=O)N2CCCC(C3OCCO3)C2)c1 +Cn1nc(CNC(=O)c2ccc(C#N)cc2)cc1-c1ccncc1 +CCCn1nnnc1CSc1nc2ccccc2c(=O)n1C1CC1 +O=C(NCc1ccccc1)c1nc2c(o1)CN(Cc1ccccc1)C2 +CN1CC(C(=O)NCc2cccc(F)c2)CC1=O +CS(=O)(=O)Nc1ccc(Nc2ncnc3sccc23)cc1 +COCCNC(=O)c1nc[nH]c1C(=O)NC(C)C +CCn1ccc(C(=O)Nc2nnc(CSc3ccccc3)o2)n1 +CN(CC(=O)NCCc1cccc(O)c1)S(=O)(=O)c1ccccc1 +Cc1noc(C)c1CC(=O)N(C)CCc1ccccn1 +Cc1ccc(C)c(OCC(=O)N(C)CCC#N)c1C +CCCC(C)CN1C(=O)C(=O)c2cc(OC)ccc21 +Cc1ccc(C2C3C(=O)CCCC3=Nc3ncnn32)cc1 +Cc1cnn(-c2ccc(C(=O)Nc3ccc(CNC(N)=O)cc3)cc2)c1 +CCCCS(=O)(=O)NC(C(N)=O)c1ccccc1 +COc1ccc(C2CC(O)C(O)C2NCc2cccc(C#N)c2)cc1 +COC(=O)c1ccccc1OS(=O)(=O)c1ccc(F)c(F)c1 +O=C(Nc1sc2c(c1C(=O)NC1CC1)CCC2)c1ccccc1 +C=CCn1nnnc1NCc1ccc(-c2cccc(Cl)c2)o1 +CC(NC(C)c1ccc(F)c(F)c1)C(=O)Nc1ccccc1C#N +O=C(CSc1nnc(-c2cccs2)o1)c1ccc2c(c1)OCO2 +CCOC(=O)N1CCN(CC(=O)c2ccc(O)cc2O)CC1 +Cn1c(=O)c(CCC(=O)Nc2ccc3[nH]ccc3c2)nc2ccccc21 +Cn1cc(CNC(=O)NC2CCCN(C(=O)OC(C)(C)C)C2)cn1 +CCCc1nc(NCc2cc(=O)[nH]cn2)c2cnn(C)c2n1 +CCNC(=O)N1CCN(CC(=O)NCC2CCCCC2)CC1 +CC1CCc2nc(CN3CCC(n4cccn4)CC3)sc2C1 +CCCN(CC(=O)Nc1ccc(Cl)cc1)C(=O)c1cc(C)n(C)n1 +Cc1occc1-c1nnc(SCCCc2ccccc2)n1N +CN(CCC#N)CC(=O)Nc1ccc(Cl)cn1 +Cc1cccc(Cc2c(O)nc3n(c2=O)CCS3)c1 +CC(C)C(CNC(=O)C1CCCN1C(=O)C1CC1)c1ccccc1 +O=C(CSc1nnc(-c2ccccn2)o1)N1CCCCCC1 +COC(=O)N1CCCC(C(=O)NCCOc2ccccc2OC)C1 +Cn1cc(CCC(=O)N2CCCC2CC(=O)c2ccccc2)cn1 +CN(CCN1CCCC1=O)C(=O)C1CC(=O)N(C)C1c1cccnc1 +CCn1cc(Br)c(C(=O)Nc2ccc(Cl)cn2)n1 +CCCc1nc(CN2Cc3c(OC)ccc(OC)c3C(O)C2)cs1 +O=C(c1cccc2[nH]ccc12)N1CCC(CN2CCOCC2)CC1 +CCC(C)(C#N)NC(=O)c1nnn(-c2ccc(OC(C)C)cc2)c1C +O=C(CCN1C(=O)COc2ccccc21)Nc1ccc(F)cc1 +O=c1[nH]c2ccc(-c3ccnc4[nH]ccc34)cc2[nH]c1=O +Cc1cc(C)nc(-n2nc(C)c(C#N)c2NC(=O)Nc2ccccc2)n1 +NC(=O)c1ccc(OCC(=O)Nc2c(Cl)cccc2Cl)cc1 +O=S(=O)(NCC1CN2CCCCC2CO1)c1ccc(F)c(F)c1 +CC(=O)c1ccc(NC(=O)Nc2ccc(O)cc2)cc1Cl +COc1ccc(-n2cc(CNC(=O)c3ccccc3C)nn2)cc1 +CSc1ccc(CNC(=O)C2CCN(c3ccccc3)C2=O)cc1 +CCc1noc(C)c1NC(=O)NC(C)C(O)c1ccc(OC)cc1 +Cc1nc(CCNC(=O)NC2CCC(O)CC2)cs1 +COC(=O)c1ccc(NCc2noc(-c3ccoc3)n2)cc1C +COc1ccc(OCc2nnc(SCC(N)=O)n2N)cc1 +CCn1c(CNc2ncnc3[nH]nc(SC)c23)nc2ccccc21 +CCn1c(=O)[nH]c2c(C(N)=O)nc(-c3cccc(OC)c3)nc21 +COc1ccc(Cl)cc1CNC(=O)CCOc1ccccc1 +Clc1cnc(CSc2nnnn2CC2CCCO2)c(Cl)c1 +Cc1nn(C)c(C)c1NC(=O)CC1Oc2ccccc2NC1=O +COc1cc(C)c(S(=O)(=O)NCC2CCCO2)cc1C(C)C +O=C(NCc1ccc(F)cc1)NCC(O)(c1cccs1)C1CC1 +Cc1cccc(NC(=O)CNc2ccc(C(=O)N(C)C)cc2)c1C +COc1ccccc1C(C#N)NC(=O)CCOc1ccccc1F +CNC(=O)c1cc(Cl)ccc1NCC(=O)N1CCCC(C)C1 +Cc1sc2[nH]c(=O)n(-c3ccccc3)c(=O)c2c1C +COc1ccc(-c2cc(C)n(C(C)C)c(=O)c2C#N)c(OC)c1 +Cc1c(C2CCN(C(=O)NCc3ccco3)CC2)noc1N +Cc1cc(C(=O)NC2CCN(C(=O)c3ccoc3C)CC2)no1 +CC1CN(CCNC(=O)c2ccn(-c3cccc(F)c3)n2)CC(C)O1 +C#Cc1cccc(N(C(=O)c2ccc(NC(C)=O)cc2)C(C)C)c1 +Cc1nc(CNC(=O)Cn2nc(C)c(Cl)c2C)c(C)s1 +Cn1c(=O)c(=O)n(C)c2cc(N3CCOCC3)c(N)cc21 +Cc1sc(NC(=O)c2cc(C)n(C(C)C)n2)c(C#N)c1C +Cc1cc(NC(=O)CN(C)C(=O)c2ccc(C(C)(C)C)cc2)no1 +CC(C)N1CC(C(=O)N2CCC(C)(C)C2)CC1=O +CC(C)C(=O)N1CCCC1C(=O)OCc1ccc(C#N)cc1 +Cc1[nH]c2ccccc2c1C(=O)OCCOC(C)C +CCCNC(=O)c1cccc(C(=O)Nc2cccc(-n3cnnc3)c2)c1 +CSc1ccccc1NCC(=O)Nc1c(C)nn(C)c1C +Cc1cc(NC(=O)c2ccc(NC3CC3)nc2)n(C)n1 +Cc1nc(CNc2ccc(-n3cccn3)cc2)cs1 +O=c1c2cnn(-c3ccccc3)c2ncn1CC(O)c1ccccc1 +Cc1cc(CCCCCCO)nc(N2CCCC2)n1 +CC(=O)c1cc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)n(C)c1 +O=C(C1CCCN(c2cn[nH]c(=O)c2)C1)N1CCCCCC1 +Cc1nnc2n1CC(NC(=O)C1Cc3cc(Cl)ccc3O1)CC2 +CCCC(=O)N1CCCC1C(=O)N(C)C1CCC(C)CC1 +CCOC(C)C(=O)NCC1(c2ccccc2C)CCOCC1 +Cc1nc(-c2cnn(Cc3ccccc3)c2)n(C)n1 +COc1cccc(NC(=O)c2ccc(F)c(C)c2)c1 +CCN(CC(=O)NC(C)C)C(=O)Cc1ccccc1OC +COCCn1cnnc1CCNc1nc(C)nc2c1cnn2C +CC(C)c1nc(C(C)NCc2cnc(N3CCOCC3)nc2)cs1 +O=C(Nc1ccc(N2CCCC2=O)c(Cl)c1)c1cnccn1 +CCc1noc(CC)c1CNC(=O)N1CCN(CC(F)F)CC1 +C=CCNC(=O)C(N)c1cc(Cl)ccc1Cl +Cc1cccnc1NC(=O)c1ccc(-c2cccs2)nc1C +CCCC(NC(=O)c1cccc(-n2cnnc2)c1)c1ccccc1 +Cc1ccc2c(c1)cc1c(=O)n(CC(=O)NC3CCCC3)nc(C)n12 +O=C(C1CCOCC1)N1CCCC(c2ccn[nH]2)C1 +O=C(c1ccccn1)N1CCC(c2nc(-c3ccccc3)cs2)CC1 +Cc1ccc(C#N)cc1NC(=O)Nc1ccccc1 +COc1ccc(-c2nnn(-c3cccc(C)c3)c2N)cc1C +COCCNC(=O)CCOc1cccc(Br)c1 +Cn1ccc2ccc(C(=O)NCc3ccccn3)cc21 +O=C1CN(C(=O)c2ccccc2SCc2cscn2)CCN1 +O=C(Cc1cccc(F)c1F)NCC(O)c1c(F)cccc1F +O=C(c1cccc(-n2cnnn2)c1)N1CCCCC1C1OCCO1 +COc1ccccc1CCNC(=O)c1sc2nc[nH]c(=O)c2c1C +Cc1nc(COc2cccc(C(=O)Nc3nnc(C)s3)c2)cs1 +Cc1noc(NC(=O)CCCOc2ccc(Cl)cc2)n1 +Cc1nn(CCOc2ccccc2C(F)(F)F)c(N)c1C#N +COc1cccc(-c2nc(-c3ccc4nnc(C)n4c3)no2)c1OC +CC(=O)N1CCC(NC(=O)NCc2ccsc2)CC1 +COCCN(C)C(=O)Nc1cc(OC)cc(C(F)(F)F)c1 +CS(=O)(=O)NCCCN1CCCc2cc(Br)ccc21 +CCNC(=O)CN1CCN(C(=O)Cc2ccccc2OC(C)C)CC1 +CCc1ccccc1-n1nnc(CO)c1CC(C)C +CCOc1cc(NS(=O)(=O)c2cccc(Cl)c2)ccc1OC +COc1cc(C)c(S(=O)(=O)N2CCCCC2CO)c(C)c1 +Cc1cc(Cn2cnc3scc(-c4ccc(C)s4)c3c2=O)no1 +CC(C)CCCC(C)NC(=O)Cn1cnc2sccc2c1=O +CCC(C)(CC)NC(=O)NCCc1ccc(S(C)(=O)=O)cc1 +Cc1cc2c(SCc3nc(-c4ccco4)no3)ncnc2s1 +O=C(Cc1ccc2c(c1)OCCO2)N1CCCC1c1ccc[nH]1 +O=C(Nc1cccc(-n2cccn2)c1)NC(CO)c1ccccc1 +O=C(c1ccc(N2CCCC2)nn1)N1CCCC1Cn1cccn1 +CCS(=O)(=O)N(C)Cc1csc(C#CCCO)c1 +COc1cccc2cc(C(=O)NCCNC(=O)C3CC3)oc12 +Cc1ccc(CNC(=O)Cn2c(C)nc3onc(C)c3c2=O)o1 +CC(C)S(=O)(=O)c1ccc(C(=O)C2CCCCC2)cc1 +COc1ccc2c(c1)CCCN2C(=O)Cn1nccc1-c1ccncc1 +Cc1ccc(C(=O)NCC(=O)N2CCCc3ccccc32)s1 +COc1cccc(COC(=O)Nc2ccccc2)c1OC +CC(C)C(=O)c1ccccc1NC(=O)Cn1ncn2nccc2c1=O +Cc1cccc(NC(=O)N2CCN(C)c3ncccc32)c1C +CC(=O)c1nn(C)c2ccc(Br)cc12 +COc1ccc(NC(=O)c2cccnc2)c(C(=O)NC2CC2)c1 +O=C(Cc1n[nH]c2cc(Cl)ccc12)Nc1ccc2c(c1)OCCO2 +O=C(c1ccc(-c2ccccc2CO)nc1)N1CCCCC1 +O=C(CCCc1cc(F)ccc1F)Nc1ccncc1 +COC(=O)NCC(=O)Nc1cccnc1N(C)C +CC(C)c1ccc(C2CC2C(=O)N(C)CCN2CCCC2=O)cc1 +O=C1CCC(C(=O)OCc2cc(-c3cccs3)on2)N1 +CCN1CC(C(=O)Nc2cc(-n3cnnn3)ccc2F)CC1=O +Cc1nc(-c2c(C)ccc(O)c2N)c2ccccc2n1 +CC(=O)c1nc2ccccc2n1Cc1cccnc1N +Cc1oc(C(N)=O)cc1COc1ccc(C(N)=O)cc1 +Cc1cnc(C(=O)N2CC(NS(C)(=O)=O)C(C(C)C)C2)cn1 +Cc1cc(C(=O)Nc2cc(F)cc(N3CCCC3)c2)n(C)n1 +Cc1cc(C)cc(N2CC(C(=O)NCc3cccnc3)CC2=O)c1 +COCCn1cc2c(n1)C(CNC(=O)c1ccoc1)OCC2 +CCOc1ccccc1CNC(=O)N1CCCC(C)C1 +CS(=O)(=O)NCCCSc1ccc(C#N)c(C(F)(F)F)c1 +CS(=O)(=O)c1ccc(C(=O)Nc2nnc(C3CCCO3)o2)cc1 +CCCn1c(SCC(=O)c2ccccc2OC)n[nH]c1=O +CCOC(=O)C1=C(C(=O)OCC)CN(C2CCCCC2)C1 +OCCCc1nc2n(n1)C(c1cccs1)CC(c1cccs1)=N2 +CC(C)n1c(=O)c2sccc2n(Cc2ccccc2)c1=O +Cc1cccc(C(=O)OCc2c(C)noc2C)c1O +Cc1nn(CCO)c(NC2CCCC(C3CC3)C2)c1C +CC(C)CC(=O)Oc1ccc(OCc2ccncc2)cc1 +Cc1ccc2nc(COc3ccc4c(c3)OCO4)cn2c1 +Cc1cccc(-n2nnc(-c3nnc(-c4ccco4)o3)c2C)c1 +COc1cc(C)c(C(=O)N2CCN(c3nccs3)CC2)cc1OC +O=C(OCc1cccnc1)C1CC1c1ccccc1 +CC1CC1C(NC(=O)NCCc1nnc2n1CCC2)c1ccccc1 +CS(=O)(=O)NCC1CCCC2(CCN(C(=O)C3CC3)C2)O1 +Cc1nscc1C(=O)NCc1nc(-c2ccc(Cl)cc2)no1 +CCOc1ccccc1CCC(=O)Nc1cc(C)ccn1 +Cc1ncsc1C(=O)NC(Cn1nc(C2CC2)ccc1=O)C(C)C +COc1ccccc1CCNC(=O)NCCNC(C)=O +Cc1nnc(NC(=O)C2CCCN(S(C)(=O)=O)C2)s1 +COc1ccc(OC)c(S(=O)(=O)NC(C)C#N)c1 +CC(C)N(Cc1ccccc1)C(=O)CSc1ncn[nH]1 +O=C(OCCN1CCOC1=O)c1ccc(-c2cscn2)cc1 +CC(C)(O)CN(Cc1ccccc1)C(=O)Nc1cccc(C#N)c1 +COc1cc2c(cc1Br)CCN2C(C)=O +COc1ccccc1N1CCN(CC(=O)c2ccc(F)cc2)CC1 +Nc1c(NCCc2ccncc2)ccc2scnc12 +CCCCNC(=O)N(C)Cc1csc(C#CCO)c1 +Cc1c(F)cccc1C1NCCc2c(F)cc(O)cc21 +COCCC1(C(=O)Nc2ccc(Oc3cccnc3)nc2)CC1 +CN1CC(C(=O)Nc2ccc(N3CCCCC3)cn2)CC1=O +CN(C)c1ccc(NC(=O)c2ccc(OCC3CCCO3)cc2)cn1 +CCN(CC)C(=O)c1cccc(NC(=O)c2cc(C)ccc2C)c1 +Cc1cc(C)n(Cc2cccc(NC(=O)NCc3ccnn3C)c2)n1 +CC(=O)Nc1nnc(SCC(=O)Nc2ccc(F)c(F)c2)s1 +CCCCCc1nnc(NC(=O)NCc2ccoc2)s1 +Cc1nn(C)c(C)c1C(=O)NCc1ccc(CN2CCOCC2)cc1 +O=C(Cc1ccc(F)cc1)NCCNc1ncnc2sccc12 +Cc1ccc(-c2nnc3n(C(C)C)c4c(=O)[nH]c(=O)n(C)c4n23)cc1 +O=C(c1ccoc1)N1CCC2(CC1)C(=O)Nc1ccccc12 +CCCC(CC(=O)OC)c1cc(C(C)(C)C)ccc1C +O=C(NCc1cccnc1OC1CCCC1)N(CCO)C1CC1 +Cc1nn(C)c(C)c1C(=O)Oc1ccc(Cl)cc1 +O=C(Nc1c(-c2cccs2)nc2ccccn12)c1ccncc1F +O=C(Cn1cc(Br)ccc1=O)NCC(F)(F)F +CC(CNC(=O)C1COc2ccc(F)cc2C1)CC1(C)OCCO1 +CC(C)n1nccc1NS(=O)(=O)c1ccccc1C(F)(F)F +CC(CC#N)N(C)C(=O)Nc1ccc(S(C)=O)c(F)c1 +O=C(CN1CCc2ccccc21)Nc1ccc(N2CCOCC2)cn1 +CC(=O)NC(C(=O)N(C)Cc1ccc(O)cc1)C(C)C +O=C(OCCc1ccccc1)C1CCOc2ccccc21 +O=C1CCN(C(=O)CCc2c[nH]c3ccccc23)CCN1 +CC1(C)CCCN1C(=O)c1c[nH]c2cccc(F)c12 +Cc1ccc(NC(=O)C2CN(C(=O)c3cccs3)C2)cc1Cl +Cc1ccc(S(=O)(=O)NC(C)Cc2ccsc2)s1 +CC(C)c1ccc(-c2cc(C#N)nn2CCO)cc1 +COc1cc(C)sc1C(=O)NCC(=O)N1CCc2ccccc21 +CC(=O)c1cc(Br)cc(F)c1OCC(=O)N(C)C(C)C +COc1ccccc1CN(C(=O)c1ccc(C)nc1C)C1CC1 +Cc1cc(N2CCCC2c2c(C)nn(C)c2C)nc(N)n1 +CN(C(=O)c1ccc(Cl)cn1)c1ccc2c(c1)OCO2 +Cc1ccc(C)c(NC(=O)CC2NCCc3ccccc32)c1 +O=C(COC(=O)c1ccco1)NCC1CCCCC1 +Cc1cc(NC(=O)C2CCN(C(=O)c3cccs3)CC2)n(C)n1 +Cc1ccc(NC(=O)c2ccc3nnc(C)n3c2)cc1F +COc1ccc(C2CCCN2C(=O)Cn2ccc(=O)[nH]c2=O)cc1 +NC(=O)C1Cc2ccccc2N(S(=O)(=O)Cc2ccc(F)cc2)C1 +CC(NS(C)(=O)=O)C(=O)NCc1ccc(Cl)cc1 +CN(CCn1cccn1)Cc1cc(Br)cs1 +COc1ccc(-c2nc3ccccc3n2C(C)C(C)=O)cc1OC +CC(C)CS(=O)(=O)c1ccc(N(C)C)c(N)c1 +CCC(C)NC(=O)CNC(=O)c1ccc(C)c(C)c1 +CCOCCn1cnc2scc(-c3ccc(F)cc3)c2c1=O +CN(Cc1ccccc1)c1ncccc1CNC(=O)C1CNC(=O)C1 +Cc1ccc(-n2nnnc2SC(C)C(=O)N2CCCCCC2)cc1 +O=c1c(F)cn(C2CCCO2)c(=O)n1Cc1ccc2ccccc2n1 +CCCC1CN(C(=O)c2ccc(CSc3nccn3C)o2)CCO1 +COCc1nc2n(n1)CCCC2Nc1ccc(C#N)cn1 +Cc1ccc(F)c(NC(=O)c2cc(Cl)ccc2-n2cnnn2)c1 +Cc1ncc(CNC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)s1 +Cc1nnsc1C(=O)OCc1cc(F)cc(F)c1 +Cc1ccc(CNC(=O)Cc2c(C)c3ccc(O)cc3oc2=O)cc1 +Cc1ccn2c(=NC(=O)C3CCCc4[nH]ncc43)[nH]nc2c1 +CC(C)C(C)(C#N)NC(=O)CN1CCN(CC(=O)N2CCCC2)CC1 +CC1(C)CN(C(=O)c2c[nH]c(=O)[nH]2)CCC1(O)CN1CCOCC1 +CC1CN(Cc2cccc(NC(C)c3cccnc3)c2)CC(C)O1 +CCc1noc(C)c1C(=O)NC(Cc1ccc(C)cc1)c1ccccn1 +COCC(=O)N1CCC(c2nc3ccc(C(F)(F)F)cc3[nH]2)C1 +COC(=O)c1ccc2nc(NC(=O)c3ccc(N)cc3)sc2c1 +CC(=O)Nc1ccc2c(c1)C(=O)c1cc(Cl)ccc1-2 +Cc1n[nH]c(C)c1CNC(=O)c1cc(C)n(C(C)C)c1C +NC(=O)c1ncc(Br)c2cccc(Cl)c12 +Cn1nc(C2CCC2)cc1NC(=O)NCCc1ccc(O)cc1 +Cn1cccc1C(O)CNC(=O)NC1CCCCC1 +CC(O)CC(C)(C)CNC(=O)Nc1ccc(F)cc1 +CCCOc1ccc(-c2cn3cc(N)cc(OC)c3n2)cc1 +CCC(C)n1ncc(C(=O)N2CCN3C(=O)NCC3C2)c1C1CC1 +C#CCNC(=O)CNC(=O)C(C)Oc1ccc(F)cc1Cl +CCN(CC)C(=O)CCC(=O)Nc1ccc(-c2nncn2C)cc1 +CCn1nc(C)c(CCC(=O)Nc2cccc(C)n2)c1C +CC(=O)c1cccc(S(=O)(=O)NCC2CCCC2)c1 +CCC1C(=O)Nc2c(C)cc(C(O)CC(C)C)cc21 +Cc1cccc(OCC(=O)Nc2ccc(C)c(N3CCCC3=O)c2)c1 +Cc1ccn(Cc2nc3c4cnn(C)c4ncn3n2)n1 +O=C(CCn1cccn1)NC1CCCc2ccccc21 +CCc1ccc(C(=O)NCCc2ccc(C)c(OC)c2)o1 +Cn1ncc2c1ncn1nc(-c3cccc(Br)c3)nc21 +CC(C)N(C)C(=O)C1CCC(=O)N(CCc2cccc(F)c2)C1 +CN1CC(C(=O)NCCc2cccs2)CC1=O +CCN(CC)C(=O)NCCC(=O)Nc1ccc(C)cc1Cl +Nc1cc(S(=O)(=O)N2CCOCC2)cc2c1NC(=O)C2 +Cc1cc(NCC(=O)NC2CCC(C)CC2)ccc1C(=O)N(C)C +Cc1cc(Nc2nncs2)nc(C2CN(c3ncccn3)C2)n1 +CCc1cnc(NC(=O)N2CCN(CCOC)C(=O)C2)s1 +O=C(NCCCOCc1ccco1)c1cnc2sccn2c1=O +CCN(CC(=O)N(C)C)S(=O)(=O)c1ccc2c(c1)OCCO2 +CC1=C(C(=O)Nc2ccccc2)C(c2cccc(C)c2)NC(=O)N1 +O=C(Nc1ccc2c(c1)S(=O)(=O)C=C2)c1ncoc1-c1ccco1 +O=C(COC(=O)C1(CC(=O)N2CCOCC2)CCCC1)c1ccc[nH]1 +COC1C(C)C(NC(=O)c2cnc3c(c2)c(C)nn3C)C1(C)C +CCCN(CC1CCCCC1)C(=O)Nc1ccnc(C(=O)N(C)C)c1 +COC(=O)c1cccc(-c2noc(-c3ccnnc3)n2)c1 +Cc1nn(C(C)C(=O)NC2CCCC2)c(=O)c2cc3occc3n12 +Cc1cc(C)n(-c2ccc(CSc3nncn3C3CC3)cc2)n1 +CCCC(=O)NCC(=O)Nc1cc(C(F)(F)F)ccc1N(C)C +Cc1ccc(C)c(C(=O)NCC(=O)N2CCCCC2)c1 +COc1cccc(CCC2CCCN(C(=O)c3cccnc3)C2)c1 +CCC(NC(=O)NC(C)CC(O)c1ccco1)c1cccs1 +CCOCCC(=O)Nc1cc(S(C)(=O)=O)ccc1F +COc1cc2c(C(C)=O)c(C)n(-c3ccccc3)c2cc1C(C)=O +Cc1noc(C)c1CN1CC2(CCN(c3cnccn3)CC2)CC1=O +Cc1cccc(C)c1NC(=O)C(C)S(=O)(=O)c1ccccc1F +Cc1cc(NC(=O)Nc2ccn(C)n2)ccc1-n1cnnn1 +Cc1ccc(F)c(-n2nnnc2Cn2nnc(-c3ccsc3)n2)c1 +CC(C)(C)OC(=O)N1CCC(=O)C(C(F)(F)F)CC1 +CCOC(=O)C(O)Cc1cc(C(C)C)c(O)cc1C +O=C(COc1cccc(NC(=O)c2ccncc2)c1)Nc1ccccc1 +Cc1ccc(NC(=O)Cn2cnc3cc(Cl)ccc3c2=O)c(C)c1 +O=C(CNC(=O)c1cccc(Br)c1)Nc1cn[nH]c1 +CNC(=O)Cc1csc(NC(=O)c2cccs2)n1 +Nc1cccnc1S(=O)CCOCC(F)(F)F +Fc1cccc(-n2nc(C3CCCC3)nc2CCCn2cncn2)c1 +CC(C)(CNC(=O)NC1CCC(O)CC1)c1ccc(Cl)cc1 +Cn1nccc1C(=O)OCCc1ccc(F)cc1F +CNC(=O)c1ccc(-c2ccc(OC)c(F)c2)nc1N +Cc1ccc(NC(=O)N2CCCC(N3CCNC3=O)C2)cc1 +CCC(Oc1cc(C)ccc1Cl)C(=O)Nc1ccon1 +O=C(N=c1[nH]c2ccccc2[nH]1)C1CC(=O)N(CCc2ccccc2)C1 +CCCc1nnc(NC(=O)NC(C)c2ccc(OC)c(F)c2)s1 +Cc1cc(OCc2nc(-c3nonc3N)no2)ccc1Cl +CCc1onc(C)c1NC(=O)CS(=O)(=O)c1ccc(Cl)cc1 +Cc1cc(C)n(Cc2cccc(NC(=O)c3cc4occc4n3C)c2)n1 +CCOC1CCN(C(=O)CCc2ccc(OC)c(F)c2)CC1 +Cc1ccccc1SC1CCN(C(=O)c2cnn(C)c2)CC1 +Cc1nc(-c2cc(C(=O)Nc3cccc(Cl)c3C)n(C)c2)cs1 +Cn1cc(Br)c(=O)c(NC(=O)Cc2ccc(O)cc2)c1 +COc1cc(C(=O)N(C)Cc2ccccc2)ccc1OC(F)F +Cc1ccsc1C1CCN(C(=O)c2ccc(C#N)nc2)CC1O +Cc1cc(C(=O)NCc2ccc(O)cc2)c(C)n1C(C)C +CCc1c(CO)nnn1CC(=O)Nc1nnc(C(C)C)s1 +CC1CN(C(=O)Nc2cccc(NC(=O)c3ccoc3)c2)CC(C)O1 +O=C(Cn1ccc(C(F)(F)F)n1)Nc1ccc(F)cc1F +CCC1c2cccn2CCN1C(=O)c1cncs1 +CC(=O)c1ccccc1-c1cc(NCc2cccnc2)nc2[nH]ccc12 +Cc1ccc(CCC(=O)NCCCC(N)=O)c(C)c1 +CC(C)C(=O)N1CCCC1C(=O)NC(C)c1nc2c(s1)CCCC2 +Cc1c(F)cccc1NCc1nsc(N(C)C)n1 +CC(CNC(=O)N(C)CC1CCOC1)c1nc(-c2ccccc2)no1 +N#Cc1ccc2c(c1)nc1[nH]c(Nc3ccccc3)nn12 +CC(Nc1cccc(N2CCOC2=O)c1)C(=O)NCc1ccccc1 +Cc1cccc(-c2ncc(CN3CCc4c(c(CO)nn4C)C3)cn2)c1 +Cn1nc(C(=O)NC(CC(F)(F)F)c2ccccc2)ccc1=O +CN(C)C(=O)c1cccc(OC(=O)c2cccs2)c1 +O=c1[nH]c2ccccc2nc1Cn1nc(-c2ccc(F)cc2)oc1=O +O=C(CSc1nc(=O)ccn1C1CC1)NCC1CCCO1 +COc1c(N)cc(C)cc1S(=O)(=O)N1CCCCCC1 +Cc1ccc(C)n1-c1nc(C(=O)N2CCOCC2)cs1 +Cc1cccc(C(N)=O)c1NCC#Cc1ccc(Cl)cc1 +CCCCS(=O)(=O)N1CCOc2ncc(C)cc21 +COc1cc(CCC(=O)c2cccnc2)ccc1OC(C)C +CC(C)(C)n1nc(C2CC2)cc1C(=O)NCCN1CCOCC1 +CCC1CCCCN1C(=O)c1ccc(CC#N)cc1 +NC(=O)C(NC(=O)CCc1ccc(F)c(F)c1)c1ccccc1 +OC(C#CCN1CCCCC1c1cccnc1)c1ccccc1 +CC(=O)N1CCC(Cc2nccnc2Cc2ccccc2F)CC1 +CC(=O)Nc1cccc(NC(=O)CSc2nc3ccccc3o2)c1 +CC(C)c1ncc(C(=O)N2CCCC2c2ccco2)cn1 +CC(NC(=O)CCNC(=O)c1ccc(F)cc1F)C1CCCCC1 +COCCOCC1NCCc2c1ccc(F)c2O +Cc1nc(-c2cccc(NC(=O)NCc3cccc(C#N)c3)c2)n[nH]1 +CCCOc1cccc2c1C(C(O)CO)NCC2 +Cc1csc(-c2ccc(C(=O)N(C)Cc3cnc(C)s3)cc2)n1 +COCCNC(=O)CSc1nncn1-c1ccccc1 +CC(CCN1CCOCC1)NC(=O)c1c[nH]nc1-c1ccccc1F +Cc1cc(NC(=O)NCc2nc(C)c(C)s2)ccc1-n1cnnn1 +CCc1c[nH]nc1C1CN(C(=O)OC(C)(C)C)CCN1 +CC1(C)Cc2cccc(CN3CCOCC34CCC4)c2O1 +CC(C)OC(=O)c1nnn(CC(=O)Nc2ccccn2)c1N +COc1cc(C2CC(O)=Nc3c2c(=O)[nH]n3C2CCCC2)ccc1O +O=C(CCc1ccsc1)Oc1cccc(F)c1 +Cc1[nH]c(=NS(=O)(=O)c2cnn(C)c2)sc1-c1ccccc1 +COC(=O)c1cc(C(C)C)sc1NC(=O)c1ccncc1 +COCCCN(C)c1cnn(-c2ccc(Cl)cc2)c(=O)c1Cl +Cc1cc(C)c2c(OCC(=O)OC3CCCC3)nn(C)c2n1 +Cc1cccc(CSc2nc(-c3cccnc3)n[nH]2)c1 +COc1cc(-c2nc3cc(C)ccc3n2C)ccc1OCC#N +COc1ccc(S(=O)(=O)N(C)C2(C#N)CCCC2)cc1 +O=C(NC1CC(=O)N(c2ccc(F)cc2)C1)C1CC1 +CCOC(=O)N1CCN(c2c(C#N)nnc3ccc(C)cc23)CC1 +O=C(NCc1cccnc1)c1ccc(Br)cc1O +OCc1nc2cc(-c3cc(NC4CCCC4)nc4[nH]ccc34)ccc2[nH]1 +O=C(NC1(c2ccc(F)cc2F)CCOCC1)c1ccon1 +CN(Cc1nc2cc(Cl)ccc2[nH]1)C(=O)c1ccc2nccn2c1 +Nc1cnc2nc(COc3ccccc3Cl)oc2c1 +CC(O)c1ccccc1NC(=O)c1ccc(-c2ccco2)[nH]c1=O +COC(=O)CCN(S(C)(=O)=O)S(C)(=O)=O +O=C(Nc1ccccc1N1CCCC1)c1cccc(N2CCCC2=O)c1 +Cc1cc(N)nc(COc2ccc3ccccc3c2)n1 +CN(Cc1ccccc1)C(=O)c1ccc(NC(=O)C2CC2)s1 +Cc1ccccc1NC(=O)Cc1cccc2cccnc12 +Cc1cc(NC(=O)N2CCC(=O)NCC2C)c(Cl)cc1F +CCOc1ccc(NC(=O)Cc2cccc(OCC#N)c2)cc1 +CC(C)Cc1cc(C(=O)N2CCCC2C(=O)N(C)C)[nH]n1 +NC(=O)C1(CNC(Cc2ccncc2)C(F)(F)F)CCOCC1 +O=C(c1cccc(-c2cc(O)cc(C(F)(F)F)c2)c1)N1CCCC1 +CC1CN(C(C)(C)CNC(=O)Nc2ccc3c(c2)COC3)CC(C)O1 +CCOc1ccccc1NC(=O)NCc1noc2ccccc12 +CCC(=O)NCc1ccccc1-c1ccc2c(c1)OCCO2 +O=C(c1ccnnc1)N1CCC2(CC1)CCN(c1ncccn1)CC2 +CC(=O)NCc1ccc(-c2csc(CCc3ccccc3)n2)s1 +CN(Cc1cnn(C)c1)C(=O)Nc1ccc2ccccc2c1 +CC(C)CNC(=O)CN1C(=O)C(N)CCc2ccccc21 +CCC(=O)N1CCN(Cc2c[nH]c(C(=O)OC)c2)CC1 +CCCC1CN(C(=O)c2ccc(OC(C)CC)cc2)CCO1 +Cc1ccc(C)c(-c2nn(CC(N)=O)c(=O)c3ccccc23)c1 +O=C(Nc1ccc(F)cc1Nc1ccccc1F)c1cc[nH]c(=O)c1 +O=C(Nc1ccccc1Cc1nc(-c2ccco2)no1)C1CC1 +CCc1ccc(NC(=O)c2nnn(-c3ccccc3)c2N)cc1 +Cn1c(C(C#N)C(=O)Cc2cccc3cccnc23)nc2ccccc21 +COC(=O)c1c(C)c(C(=O)COc2cccc(OC)c2)c(C)n1C +CCCn1cc(N)cc1C(=O)Nc1cccc(C)n1 +Cc1ccc(C(C)NC(=O)CCCCNC(N)=O)cc1F +O=C(CSc1ccccc1Cl)NCc1ccc2c(c1)OCCO2 +COc1ccccc1C(C)NC(=O)N(CC(C)(C)O)C(C)C +COCCCNC(=O)c1cccc(Cl)c1Cl +CCOC(=O)C(C)(C)NCc1cccc(F)c1F +CCCCN(C)S(=O)(=O)Nc1cnn(C(C)(C)C)c1 +COc1ccc(C(C)COC(=O)c2ccnn2C)cc1 +O=S(CCN1CCN(CCO)CC1)c1ccccc1 +CNC(=O)c1ccccc1NC(=O)Nc1cccc(Cl)c1 +CC1Cc2cc(C(=O)Nc3cccc(O)c3)ccc2N1S(C)(=O)=O +Cc1cnn(CCC(=O)Nc2ccc(Cn3cccn3)cc2)c1 +COc1ccc(CCNc2ccc(C#N)cn2)cc1 +CCOC(=O)c1ccc(N(C)CC(=O)Nc2cccc(C)c2C)nc1 +Cc1nn2c(ncc3c(=O)n(-n4cnnc4)ccc32)c1-c1ccccc1 +O=C(NCCN1CCOCC1)C1(c2ccccc2)CC1 +CN(CC(=O)Nc1cccc(F)c1)C(=O)C1CC1 +Cc1nn(C)cc1S(=O)(=O)NCc1ccc(F)cc1 +N#Cc1ccc(CCC(=O)NC2CCN(c3nccs3)CC2)cc1 +CC(O)(CCc1ccccc1)CNC(=O)NCc1ccc(F)cc1 +O=C(c1ccc(O)cc1)N1CCN(Cc2c(F)cccc2Cl)CC1 +Cc1cc(C)n(CC(=O)Nc2cccc(F)c2)c(=O)c1C#N +COCc1cccc(CNC(=O)COc2cc(F)cc(F)c2)c1 +CCCCN(CC)C(=O)c1cc(Cl)ccc1N +CCOC(=O)c1cccnc1N1CCCC(c2cc[nH]n2)C1 +CC1COC2(CCN(c3cncc(Br)c3)CC2)O1 +O=C(OCCc1c[nH]nc1C(F)(F)F)C1COc2ccccc21 +O=C(CSc1ccccc1)N1CCN(C(=O)c2ccccc2)CC1 +CCS(=O)(=O)N1CCCC(C(=O)Nc2cccnc2)C1 +Cc1nn(-c2ccc(C(=O)Nc3cccc(O)c3)cc2)c(C)c1Cl +CC(C)OCCSc1ncnc2c1cnn2-c1ccc(F)cc1 +Cc1oc(C)c(C(=O)N2CCN(C(=O)N3CCCCC3)CC2)c1C +CC(NC(=O)CCNC(=O)OC(C)(C)C)c1ccc(C#N)cc1 +Cc1cc(C)n(CCCNC(=O)Cc2c[nH]c3ccccc23)n1 +Nc1ccn(Cc2ccc(OC(F)(F)F)cc2)n1 +Cc1cc(C)nc(SCC(=O)Nc2ccccc2)n1 +CC(NC(=O)CCCc1nc(-c2cccs2)no1)C1CC1 +Cc1nnc(CN(Cc2ccc(-c3ccc(F)cc3)s2)C(C)C)o1 +Cc1ccc2c(c1)N(C(=O)CCSc1ccccn1)CCC2 +CC1CN(C2CCN(C(=O)C3(c4ccc(F)cc4)CC3)CC2)CCO1 +Cc1cc(O)c2c(c1)C(c1cc[nH]c(=O)c1)NCC2 +NC(=O)C1CCN(C(=O)CCCOc2ccc(F)cc2)CC1 +CCN(Cc1ccncc1)C(=O)c1ccc(N)nc1 +CC(NC(N)=O)C(=O)Nc1cccc(Br)c1 +COc1ccc2c(c1)CCCN2C(=O)COc1ccc(C)nc1 +COc1c(-n2nc3ccccc3n2)cc(C)cc1S(N)(=O)=O +O=C(CCc1nc(-c2ccc(F)cc2)no1)NCCc1cccs1 +COC(=O)C(CC#N)NC(=O)OBr +O=C1COc2ccc(Cl)cc2N1CCCCO +COc1ccc(C(=O)Nc2ccc3c(c2)OCO3)c(OC)c1 +COc1ccc(C(C)N(C)C(=O)Nc2ccc(OC)nc2)cc1 +Cc1ccccc1C(C#N)NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +CNc1snc(C)c1C(=O)Nc1ccc2oc(C(C)C)nc2c1 +CN(CCc1ccccn1)C(=O)CNC(=O)c1ccc2ccccc2c1 +CCCC(C)C(=O)Nc1ccc(S(=O)(=O)NC2CC2)cc1 +CC(C)(C)C(=O)N1CCC(c2ccsc2)CC1 +CC(C)(C)N(Cc1ccccc1)C(=O)CN1CCN(CC(N)=O)CC1 +CCOC(=O)c1cccnc1NCc1nnc2ccccn12 +Cc1ccc(C2(O)CCN(c3cccc(C(F)(F)F)n3)CC2)nc1 +CNC(=O)CN(C)S(=O)(=O)c1cc(OC)ccc1OC +CCCOc1cc(S(=O)(=O)NCC)ccc1Br +N#CCSc1nnc(-c2ccccc2Br)n1N +Cc1nn2cc(C(=O)N(C(C)C)C(C)C)nc2s1 +O=C(COc1ccc(F)cc1)NCCc1nc2ccccc2[nH]1 +Nc1c(-c2ccc(Cl)cc2)ncnc1N1CCCCC1 +CCc1cccc(OCCCN(C)C(=O)c2ccc3[nH]nnc3c2)c1 +Cc1noc(CNS(=O)(=O)c2ccc(Cl)cc2)n1 +N#CCCCn1ccc2c(Cl)c(Cl)ccc2c1=O +CCc1nnc(SCC(=O)Nc2ccccn2)n1-c1ccccc1 +O=C(Nc1ccc(OS(=O)(=O)c2ccccc2)cc1)C1CC1 +Cc1nnc2ccc(C(=O)Nc3ccccc3O)cn12 +CN1C(=O)CC(NC(=O)Nc2cccnn2)C1c1ccc(Cl)cc1 +Cc1nn(-c2ccccc2)cc1C(=O)NCCC(=O)N(C)C +CNS(=O)(=O)c1cc(C(=O)NC(C)c2ccccn2)ccc1OC +CC(C)CCN(C(=O)C1CCN(C)C(=O)C1)C1CC1 +COc1cc(C#N)ccc1OC(=O)Cc1c(F)cccc1Cl +Cc1nnc(NCCc2cccs2)c(C#N)c1C +CCC(C(=O)OC)N1C(=O)C(C)Oc2cc(CO)ccc21 +Cc1nc2ccccc2nc1COc1ccc(CO)cc1 +COc1ccc(OC)c(S(=O)(=O)NCc2ccc3c(c2)CCO3)c1 +Cc1ccc(N2CC3(CCN(C(=O)c4ccncc4)C3)CC2=O)cc1 +O=C(NCC(F)(F)F)C1NCCc2ccccc21 +COc1cc(C(=O)NCC(C)O)cc(Cl)c1OCC(C)C +CC(C(=O)N(C)CC(=O)NCC(=O)Nc1ccccc1)n1cccn1 +CC(=O)c1ccc(NC(=O)c2cccc(CN3CCCC3=O)c2)cc1 +Nc1nc(CSc2nnc(C3CCCCC3)o2)nc2ccccc12 +CCOC(=O)c1ccc(C)c(NS(C)(=O)=O)c1 +CCC1Oc2cccc(N)c2N(Cc2ccc(C)cc2)C1=O +CCS(=O)(=O)c1ccc(Cl)c(C(=O)N(C)CC2CCCC2)c1 +CC(C)NC(=O)Nc1ccc(C(=O)N(C)c2cccc(C#N)c2)cc1 +CCCN(C)C(=O)NCc1cc(Br)cs1 +CC(=O)Nc1ccc2c(COC(=O)C3CC3C)cc(=O)oc2c1 +CCS(=O)(=O)c1nnc(NC(=O)c2ccco2)s1 +Cc1cc(C)c2c(c1)C1(OCCO1)C(=O)N2Cc1ccccc1 +O=C(c1ccc(Cl)cc1)N1CCCC(c2nnc3ccccn23)C1 +CN(C)C(=O)C(C)(C)NS(=O)(=O)c1cc(F)cc(F)c1 +O=C(Nc1cnc(N2CCCCC2)nc1)c1ccsc1 +CCCCC(=O)N1CCCC1C(=O)c1cccs1 +COc1c(Cl)cc(Cl)cc1CNn1cnnc1 +CCCC(C#N)NC(=O)CCOc1ccccc1Cl +CC1CCCN(C(=O)c2cccc3c2OCO3)CC1 +O=C(Nc1ccc2c(c1)COC2)c1cc(-c2ccncc2)on1 +Cc1cc(CN2CCN(C(=O)c3c[nH]c4cccc(F)c34)CC2)on1 +CC(=O)Nc1cc(S(=O)(=O)Nc2cccn(C)c2=O)ccc1F +COC(=O)c1cc(N2CCOCC2)ccc1NC(=O)c1ccsc1 +COC(=O)c1ccc(C(=O)Oc2cccc(C(C)=O)c2)s1 +CC1CN(CC(=O)Nc2ccc(Br)cn2)C(C)CO1 +COc1cc(C)c(C(=O)Nc2cc(F)ccc2O)cc1OC +Cc1cccnc1NC(=O)C12CCC(CC1=O)C2(C)C +O=C(NC1CCCCC1O)c1cccc(-n2cccn2)c1 +O=S(=O)(NCCc1ccccc1)c1ccc2c(c1)NCC2 +CC1CN(C(=O)c2ccc(-c3ccccc3)[nH]c2=O)CCO1 +CN(Cc1ccc(C#N)o1)Cc1nc2c(s1)CCCC2 +CC1Cc2ccc(-c3cc(COC(=O)C4CCC(=O)N4)no3)cc2O1 +NC(=O)C1CCN(C(=O)c2sccc2Br)C1 +CC(C)Cc1ncc(CN2CCCC(c3nnc4n3CCC4)C2)s1 +Cn1nnc(CO)c1-c1ccccc1Br +CC(C(=O)Nc1ccc(Cl)cc1F)n1nnc(-c2ccccc2)n1 +CS(=O)(=O)Nc1ccccc1NC(=O)C1CC=CCC1 +CC(=O)c1ccc(NC(=O)Cc2cnc(-n3cccc3)s2)cc1 +CC(OC(=O)c1cccnc1Oc1ccccc1)C(N)=O +Cc1cccc(CNC(=O)N(CCCCO)C2CC2)n1 +CCN(Cc1cnc2ccccn12)C(=O)CCn1ccc(=O)[nH]c1=O +O=C(NCc1csc(CCc2ccccc2)n1)c1ccco1 +CCc1c(C(=O)N2CCN(c3ccc(F)cc3)CC2)csc1C +C#CCN1CCN(C(=O)NCCNC(=O)c2cccnc2)CC1 +CC(C)(C)OC(=O)NCC1CCN(c2nccs2)CC1 +CC(C)N(Cc1cccnc1)C(=O)c1cc(Br)c[nH]1 +COc1ccc(CNc2cccc(C)c2N)cc1C +COCCC1(C(=O)NCC2CCC(C)(C)CC2)CC1 +O=C(NCC1CC1)c1cncn1-c1ccc(F)cc1 +Cc1nnc(CCCn2nnc(-c3ccc(C(C)C)cc3)n2)o1 +CC(C)C(C)NC(=O)CNc1ccc(-n2cccn2)cc1 +CC1CCCC(CNC(=O)CCNC(=O)C(C)(C)C)C1 +CCn1cc(C(=O)N2CCC(c3nc(C(C)C)no3)CC2)cn1 +O=C(NCc1ccc(Cl)cc1)c1cnn2c1OCCC2 +CCC(O)CN(Cc1ccccc1)S(=O)(=O)c1ccc(N)cc1 +CC(C)(C)c1cc(C(=O)NCC2CN3CCCCC3CO2)no1 +N#Cc1ccc(C(=O)Nc2cc(C3CC3)n[nH]2)cc1 +Cc1cc(Br)ccc1NC(=O)CCc1c(C)n[nH]c1C +Cc1ccc(C(=O)CCC(=O)N2CCCCC2)cc1N +CC(C)(C)c1cc(NC(=O)c2cnc3ccccc3n2)[nH]n1 +Cc1cccc(-n2ncc(C(=O)N(C)C)c2-n2cccc2)c1 +CC(NC(=O)NCC(F)(F)F)c1ccc(S(N)(=O)=O)cc1 +O=C(CCn1nnc(-c2cccnc2)n1)Nc1cccc(F)c1 +CCNC(=O)c1cccc(NC(=O)COc2ccc(Cl)c(C)c2)c1 +CS(=O)(=O)c1ccc(F)c(NC(=O)c2c(F)cccc2F)c1 +CCn1c(C)nnc1SCCn1cc(-c2cccc(O)c2)nn1 +CC(Oc1ccc(C#N)cc1)C(=O)NCCN1CCOCC1 +Cc1cc2occ(CC(=O)Nc3cnns3)c2cc1C +O=C1C2CC(O)CCN2C(=O)CN1CC1=CC=CC2N=CC=C12 +O=C(OCc1cc(-c2ccco2)on1)c1c[nH]c2ccccc12 +CC(C)COCC(O)CNC(=O)Nc1cccc(C#N)c1 +CCOC(=O)N1CCN(C(=O)c2cnn(-c3ccccc3)n2)CC1 +CC(C#N)CN(C)CC(=O)NCc1cc(Br)cs1 +Cc1cc(C)n(-c2ccc(C(C)C)cc2)c2nc(=O)[nH]c(=O)c1-2 +Cc1ccc(C)c(-c2nc(CC(=O)NCc3ccco3)sc2C)c1 +COCCOCC1NCCc2ccc(F)c(C)c21 +Cc1ccc(C#N)cc1Nc1c(F)cc(N)cc1F +CCOC(=O)c1cncn1C1CCCc2ccccc21 +CC(C)(C)NC(=O)c1ccc(NCC(=O)N2CCCCC2)cc1 +CCC(O)CN1CCN(C(=O)c2cc(C3CC3)n(C(C)(C)C)n2)CC1 +Cc1cnn(C(C)C(C)NCc2ccnc(-c3ccccc3)n2)c1 +CCOc1ccc(C(=O)Nc2cc(C)on2)cc1Br +CC(Oc1cccc(Cl)c1)C(=O)OCCc1cccnc1 +CC(NC(=O)c1ccccc1F)c1ccc(S(N)(=O)=O)cc1 +O=C(NCCc1c[nH]c2ccccc12)c1ccc[nH]c1=O +COCC(O)c1ccc2c(c1)C(NC(=O)C(C)(C)C)CCC2 +CC(C)(C)C(=O)N1CCN(c2ccc(S(N)(=O)=O)cc2)CC1 +COCCCC(=O)Oc1c(Cl)cccc1Cl +CC1CC(C)CN(C(=O)COC(=O)c2cccc(CC#N)c2)C1 +FC(F)c1nnc(NCc2ccc(Cl)cc2)s1 +CCN(C(=O)CCC(C#N)c1cccs1)c1ccccc1 +CCOC(=O)c1c(NC(=O)CC)sc2c1CCCC2 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1cccc(C(F)(F)F)c1 +O=C(c1ccc2c(c1)CCCC2)N1CCC(CO)CC1 +O=C(NCC1COC2(CCCCC2)O1)C1CCCC1 +Cc1c(NC(=O)c2ccc(-n3ccnn3)cc2)cnn1-c1ccccc1 +C=CCNC(=O)c1ccccc1NC(=O)Cc1noc2ccccc12 +O=C1CCCCC1Sc1nnc(NCC(F)(F)F)s1 +CC1CCCN(C(=O)c2cc3ccccc3c(=O)[nH]2)CC1 +CCn1cc(NC(=O)c2ccc(-c3nc4ccccc4s3)o2)cn1 +CCOc1ccc(NC(=O)C2(C#N)CCCC2)cc1Cl +CC(C)CCOc1cc(C(=O)NC2CC2)ccc1N +Nn1c(SCc2ccccc2)nnc1C(F)(F)F +COc1ccccc1-n1cc(C(C)n2cc(-c3ncc[nH]3)nn2)cn1 +CC(=O)Nc1ccc(NCc2cn3cccnc3n2)c(Cl)c1 +O=C(NCc1cccc(C(F)(F)F)c1)c1ccccn1 +CCc1ccc(CNS(=O)(=O)c2ccc(C)s2)s1 +CCCNC(=O)C(C)Nc1ccccc1OCC +CC(=O)Nc1ccc(F)c(C(=O)N=c2[nH]c3ccccc3[nH]2)c1 +COc1cccc(CN(C)C(=O)c2nccnc2N)c1 +CC(NC(=O)COc1ccccc1O)c1ccc(F)c(F)c1 +COc1cc(NC2CCOCC2)cc(-n2cnnn2)c1 +Cc1nc2c(ccc3nc(NC(=O)c4ccno4)sc32)s1 +CC1CCCC(CCn2ccnc2-c2cnccn2)C1 +COc1ccc(CCN2CCOC(c3noc(C)n3)C2)cc1 +C=CCn1nc(C#N)cc1-c1ccc(OC)cc1C +O=C(NCc1ccco1)C1COC2CN(c3ncc(F)cn3)CC21 +Cc1cc(C)nc(-n2nc(C)cc2NC(=O)c2ccc(Cl)cc2)n1 +CCN(Cc1ccc2c(c1)OCCO2)C(=O)NCc1nc(C)cs1 +CCc1onc(C)c1NC(=O)N(C)C(CC)CC +O=C1CCCN1CCCn1ccnc1-c1ccccn1 +CC(C)C(=O)N(Cc1ccoc1)Cc1cccs1 +FC(F)(F)Oc1ccc2c(c1)C(C1CC1)NCC2 +N#Cc1cccc(CN2C(=O)C(=O)c3cc(Cl)ccc32)c1 +NC(=O)NCC(=O)Nc1ccc(OCC(F)(F)F)nc1 +CC(=O)c1c(NC(=O)Cc2ccccc2)nc(C)nc1-c1ccccc1 +COc1ccc(C(=O)Nc2ccccc2NC(=O)N2CCCC2)cn1 +CC(=O)Nc1cccc(NCc2csc(C(C)(C)C)n2)c1 +O=C(Nc1ccnn1Cc1cccc2ccccc12)C1CCC1 +COC(=O)CN(c1ccccc1C)S(=O)(=O)c1ccccc1 +C=CCCn1nc(C)c(S(=O)(=O)N(CC)C2CC2)c1C +COC(=O)C(C)CN(C)C(=O)c1csc(-c2ccccc2OC)n1 +CCn1nc(C)c2c(C(=O)Nc3ccc(C#N)cc3)cc(C)nc21 +COCCOc1c(Cl)cccc1NC(=O)c1cccs1 +Cc1nn(CCC(=O)NC(c2cccs2)C(C)C)c(C)c1C +Cc1cccc(CN(C(=O)CCn2cncn2)C(C)C)c1 +Cc1cccc(NC(=O)NCC(=O)NCC2Cc3ccccc3O2)c1 +CNc1oc(C=Cc2cccc(OC)c2)nc1C#N +COc1ccc(-c2nnsc2C(=O)NCC2CCCO2)cc1 +Nc1nnnn1NCc1ccccc1OCc1ccc(Cl)cc1 +CC(C)(C(=O)N1CCC(C(N)=O)C1)c1ccccc1F +COc1ccc(NC(=O)Nc2cccc(Cl)c2)cn1 +CCC(=O)Nc1cccc(NC(=O)C(C)(C)C)c1C +Cn1ccnc1SCC(=O)NCc1ccccc1 +CC(=O)Oc1ccc(NCc2ccc(F)cc2)cc1 +COCCNC(=O)CCNc1ncnc2ccsc12 +COC(=O)Cc1cc(C)ccc1S(=O)(=O)C(C)C +Cc1csc(NC(=O)c2c(C)nn(C)c2C)n1 +CN(C)C(=O)Cc1csc(-c2cc(Br)cs2)n1 +Cc1c(C#N)c(N)n(CCc2ccccc2F)c1C +Cc1cnn(CC2CC2)c1NC(=O)c1ccccc1C(F)(F)F +Cc1nn(C)c(C)c1NC(=O)CN1CCn2c(nn(C)c2=O)C1 +CN(C)S(=O)(=O)c1ccc(CNc2ncnc3ccccc23)s1 +COc1ccc(OC)c(CCNC(=O)CCC#N)c1 +O=C(Cc1ccco1)N1CC2COCC2(COc2ncccc2F)C1 +Cc1nc(C2CCCN(C(=O)C3CC3)C2)c2cccnc2n1 +Cc1onc(-c2ccncn2)c1C(=O)NCCCN1CCCC1=O +CC(C)C(=O)NCc1nn(C2CCCC2)c(=O)c2ccccc12 +CCCC1=C(C(=O)OC(C)C)C(c2ccc(C)o2)NC(=O)N1 +CC(Sc1ccccn1)C(=O)N(C)Cc1nccn1C(F)F +COc1cc(C(=O)N(C)Cc2ccco2)ccc1C +CC(C)n1cc(NC(=O)c2cnc(C3CCCO3)s2)cn1 +CCOc1cc(CNC(=O)NCCC(=O)N2CCCC2)ccn1 +Cc1c(C(N)=O)nnn1-c1ccc(Cl)c(Cl)c1 +Cn1c(COC(=O)c2ccccn2)cc(=O)n(C)c1=O +CC(Oc1cccc(C#N)c1)C(=O)N1CCc2cc(F)ccc2C1 +Cc1nnc(SCC(=O)NC(C)c2ccc(CC(C)C)cc2)s1 +CC(C)CNC(=O)c1cc(=O)c2cc(F)cc(N)c2o1 +O=C(NCc1ccc(Cl)cc1)c1cc(=O)c2c(O)cccc2o1 +CC1(NC(=O)c2ccc(C(N)=O)cn2)Cc2ccccc2C1 +O=C(Cn1cc(Br)ccc1=O)OCc1ccccc1F +CCC(C)NC(=O)Nc1cccc(N(C)C(C)C)c1 +O=c1[nH]ncc2c1Sc1cn[nH]c(=O)c1S2 +COc1c(C2CCCN2C(=O)c2csc(C(C)C)n2)c(C)nn1C +CC(C)c1c(C(=O)NCc2cccnc2)cnn1-c1ccc(F)cc1 +CC(C)Oc1ccc2c(C(=O)Nc3cnn(C)c3)cc(=O)oc2c1 +COCCn1nc(-c2ccccn2)cc(C#N)c1=O +COc1ccc(CNc2ncc(-c3ccc(F)cc3)n2C)cc1 +Cc1ccc(NC(=O)CCSc2nnc(-c3ccoc3C)o2)cc1 +Cc1cnn(CCC(=O)N(C)C(C)c2ccc(F)c(F)c2)c1 +Cc1nnc(SCC(=O)c2coc3ccccc23)o1 +O=C(Cc1ccc2ccccc2c1)N1CCCN(c2cccnn2)CC1 +COc1cc(C2NCCc3cc(F)c(O)cc32)ccn1 +CSc1ccc2nc(NC(=O)CN(C)S(C)(=O)=O)sc2c1 +C#CCN1CCN(C(=O)NCC(C)Oc2cccc(C)c2)CC1 +O=C(CCn1cnc2ccccc21)NCC(O)c1ccccc1F +CCc1noc(CC)c1CNC(=O)c1ccc(Cl)c2cccnc12 +CCc1ccc(-c2ccc(C(=O)NC3CC3)c(N)n2)cc1 +Cc1nc(NC2CC2)cc(-c2cc(Cl)ccc2F)n1 +CCn1cc(Cl)c(C(=O)Nc2ccc(NC(C)=O)cc2)n1 +CCOC(=O)c1csc(NC(=O)Cc2cn3ccsc3n2)n1 +Cc1c(C(=O)N2CCCC2)sc2ncnc(N3CCCCC3)c12 +O=C(Nc1cnccn1)c1cccc(F)c1Cl +COCCCn1cc2c(c1-c1ccccc1)c(=O)n(C)c(=O)n2C +Nc1c(Cl)cccc1C(=O)NC1CCC(O)CC1 +COCCOc1ccc(NS(=O)(=O)c2ccccc2F)c(C)c1 +N#Cc1cnc2ccccc2c1NCCc1ccccn1 +CN(C)S(=O)(=O)N1CCN(c2ccccc2Cl)CC1 +Cc1nnc(CN(C)Cc2cccc(-c3ccccn3)c2)n1C +CCc1cccc(C)c1NC(=O)CNc1c(C)cccc1C(N)=O +CCc1noc(CC)c1CC(=O)Nc1cccc(C(=O)OC)c1 +N#Cc1ccc(NCCc2ccc(S(N)(=O)=O)cc2)nc1 +CC1(NC(=O)Nc2cccc(S(N)(=O)=O)c2)CCCCCC1 +CC(C)CCNC(=O)c1ccc(-c2ccc(F)cc2)nc1N +CC(=O)NC(C(=O)Oc1cc(Cl)ccc1Cl)C1CCCC1 +O=C(c1ccc2cncc(-c3ccccc3)c2n1)N1CCC(O)CC1 +CCc1ccccc1OCc1ncc(C(N)=O)c(N)n1 +Cc1nc(CC(=O)NCCC2COc3ccccc3O2)cs1 +O=C(NC12CC3CC(CC(C3)C1)C2)C1CSc2nccc(=O)n2C1 +O=C(NCCCO)Nc1ccccc1OC(F)F +CN(C)c1cncnc1-n1cc(NC(=O)c2cccs2)cn1 +COc1ccc(NC(=O)C(C)Oc2ccccc2OC)c(OC)c1 +CCOC(=O)C1CCCN(C(=O)NCCCC(C)C)C1 +CN(CCc1ccccn1)C(=O)Nc1ccccc1-n1cccn1 +COC(=O)c1cc(CN2CCCC(c3nc4ccccc4o3)C2)c[nH]1 +CCNC(=O)C(C)Sc1nccn1-c1cccc(C)c1C +CC(=O)Nc1ccc(-c2cc(=O)c3ccccc3o2)cc1 +O=C(Nc1cccc(Cl)c1)c1cccn2cncc12 +CCc1csc(-c2ccc(CNC(=O)c3cccnc3)cc2)n1 +CCOc1ccccc1Nc1ncnc2[nH]c(C)nc12 +CCc1nn2c(=O)cc(CSc3nncn3C)nc2s1 +CC(C)(C)OC(=O)N(Cc1cccs1)S(C)(=O)=O +CC(Sc1ccccc1N)C(=O)Nc1ccccc1 +COc1ccc(F)cc1C(=O)OC(C)c1nc(C)no1 +CCC1CN(C(=O)N2CCC(C(=O)NC)CC2)c2ccccc2O1 +Cc1ccccc1OC(C)C(=O)Nc1cccc(C(=O)N(C)C)c1 +CCS(=O)(=O)N1CCCC2(CC(Oc3cccnc3)CO2)C1 +CCOC(=O)C1Cc2cc3c(cc2C1=O)CC(C(=O)OCC)C3=O +Cn1nccc1CNC(CC(F)(F)F)c1ccc(F)cc1 +COc1ncnc2c1CN(c1ccc3nnnn3n1)CC2 +Cc1cccc(C(C)(C)CNC(=O)CNc2ccc(C(N)=O)cc2)c1 +CCCn1nc(C(=O)Nc2cccc(Br)c2)ccc1=O +Cc1nn(C)c(C)c1NC(=O)CCc1nc(-c2ccccc2)no1 +COc1ccc(C(=O)NCCCC(=O)N(C)C2CCCCC2C)cc1 +CN(CC(=O)N1CCC(Nc2cccnn2)CC1)c1cnccn1 +CCCCCCNC(=O)Nc1ccc(C(=O)NC)cc1 +O=C(NCc1ccccc1)N1CCN(CC(O)c2ccco2)CC1 +CS(=O)(=O)N1CCN(C(=O)Nc2cc(F)ccc2F)CC1 +CCOC(=O)N1CCN(c2ncnc(NCCC(C)C)c2N)CC1 +O=C(c1ccc(-n2ccnc2)nc1)N1CCCc2ccccc21 +COCCC(=O)Nc1ccccc1N(C)C1CCCC1 +CCc1ocnc1C(=O)NC1CC(=O)N(CC2CCCCC2)C1 +CC(O)c1nc2ccc(F)cc2n1Cc1ccc(F)cc1 +Cc1cc(C(=O)NC(C#N)c2ccc(Cl)c(Cl)c2)n(C)n1 +CN1CC(C(=O)N2CCCC2c2cccc3ccccc23)CC1=O +CCC(NC(=O)c1ccc(OC)nn1)c1nc(C)cs1 +CN(C)c1c(Cl)cccc1NC(=O)N(Cc1ccccn1)C1CC1 +CC(=O)c1cccc(NC(=O)c2ccc3c(c2)nnn3C(C)C)c1 +COCCNC(=O)CN1CCc2cc(S(N)(=O)=O)ccc21 +O=C(Cn1cnnn1)N(Cc1cccnc1)Cc1ccco1 +Cc1ccsc1CN(CCCO)Cc1cccc(F)c1 +Cc1cccc(CNc2ccc(CC(=O)N(C)C)cc2)c1 +COC(=O)c1ccc(C(C)Sc2nnc(C(F)(F)F)n2N)o1 +COc1cccc(C(=O)NCC(C)(O)c2ccc(F)cc2)c1OC +COc1cccc2c(=O)c(C(=O)Nc3ccc(CCO)cc3)c[nH]c12 +Cc1cc2c(cc1S(=O)(=O)NCc1ccccc1)NC(=O)CO2 +C=CCNS(=O)(=O)Cc1ccc(NC(=O)C2CC3CCC2C3)cc1 +CC(C)OCCNC(=O)c1cc(-c2ccco2)on1 +Cc1ccnn1CCNC(=O)c1cnc(C(C)(C)C)nc1 +O=C(Nc1ccc(F)c(F)c1)c1coc(NC(=O)c2cccs2)n1 +Cc1cccnc1NC(=O)CCn1c(C)c(C)sc1=O +CCC(=O)N(C)CC(=O)Nc1ccc(Br)cc1C +Cn1cc(C(=O)N2CCc3ccccc3C2)c2ccccc21 +NC(=O)C1(CNC(=O)COc2ccccc2F)CCOCC1 +CC(Sc1ncnc2nc[nH]c12)C(=O)c1ccc(Cl)cc1 +COCC12CCOC1CCN(C(=O)CCOc1ccccc1)C2 +CC(C)(CO)CCCNC(=O)N1CCCC(CC(N)=O)C1 +O=C(Nc1ccc2c(c1)OCO2)c1ccc2[nH]cnc2c1 +Cc1nc(C(=O)N(C)C)ccc1-c1nc(-c2ccncc2)no1 +Cc1c(C(=O)NCc2ccc(Cl)cc2)cnn1-c1ccncc1 +Cn1c(SCC(=O)N(Cc2ccccc2)C2CC2)nnc1C1CC1 +O=C(Nc1ccc(F)cc1F)N(CCC(F)(F)F)CC(O)CO +CC(C)c1nc(CC(=O)N(Cc2ccco2)CC2CCCO2)cs1 +Cc1cn(-c2ccccc2)nc1NC(=O)C1CC=CC1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)NCC(C)C1CC1 +CCCC(=O)NCC(=O)N(C)C1CCCC(C)C1 +Nc1cccc2c1N(C(=O)c1cccs1)CCC2 +CCOCCNC(=O)N1CCN(C(=O)CCC2CCCC2)CC1 +COc1cccc(CNC(=O)CCn2ccc3ccccc32)c1 +COC(=O)C(C)N1CCc2c(cc(OC)c(OC)c2OC)C1 +CCOC(=O)C1CCCN(C(=O)c2ccccn2)C1 +O=C(COc1ccccc1)c1ccc2c(c1)CCN2 +N#CCc1ccc(NC(=O)CCn2c(=O)oc3ccccc32)cc1 +CC(Sc1nnc(NC2CC2)s1)C(=O)c1ccccc1 +CCn1nc(C(=O)NC2CCCCC2)c(=O)c2cc(F)ccc21 +COC(=O)c1c(C)[nH]c(C(=O)OC(C)C(=O)N2CCCC2)c1C +CCc1ccc(OC(=O)CCSc2nnnn2C)cc1 +O=C(NC1Cc2ccccc2NC1=O)c1cccs1 +CN(CCN(C)c1ccccc1)C(=O)Nc1cn[nH]c1 +CCNC(=O)CNC(=O)NC1CC(C)(C)Cc2oc(C)cc21 +N#Cc1ccc(C(=O)N2CCN(CCO)CC2)cc1 +Cc1cc(C)n(-c2cccc(CNc3nnc(C)o3)c2)n1 +CC(c1ccc(Cl)cc1Cl)N(C)C(=O)Nc1cn[nH]c1 +O=S(=O)(NCC1CCCCO1)c1cccc(Cl)c1F +Cn1cc(S(=O)(=O)N2CCN(CC(N)=O)CC2)cc1C(N)=O +COCCCNC(=O)CCc1nc2ccccc2s1 +COCCC(=O)Nc1cc(Br)c(=O)n(C)c1 +COc1ccc(Cl)cc1NC(=O)NCC(=O)NC1CC1 +CCOc1ccc(N2CC(NC(=O)Nc3ccncc3)CC2=O)cc1 +Cc1ccccc1N1CCN(C(=O)c2nn(C)c3ccccc23)CC1 +COC(C)c1nc(C)c(-c2nc(C(C)(C)OC)no2)s1 +CCNC(=O)N1CCC(Oc2cnccn2)CC1 +CCCNC(=O)NCc1cccc(OCC(F)(F)F)c1 +COc1cccc(OS(=O)(=O)c2ccc(C#N)cc2)c1 +O=C(Nc1cccc(CO)c1)c1c[nH]c(=O)[nH]c1=O +CCN1CCN(c2ccc(NC(=O)Cc3ccccc3C)cn2)C1=O +CC(C)CNc1ccc(C(=O)NCc2noc(C(C)C)n2)cn1 +COc1ccccc1C(=O)NCC(=O)c1cc(F)ccc1F +OC(c1ccc2c(c1)OCCO2)c1ccccc1F +COc1ccc(OC)c(CN(C)C(=O)c2ccc(C)cc2O)c1 +COC(=O)c1c(NCC(C)O)c2cccc(Cl)c2[nH]c1=O +CC(C)Cc1nc(CNC(=O)c2coc(C3CC3)n2)no1 +N#Cc1cc(NC(=O)CCn2cnc3ccccc32)ccc1F +Cc1cc(NC(=O)CNc2ccc(F)c(Cl)c2)on1 +C=CCN(CC(F)(F)F)C(=O)CCn1c(=O)oc2ccccc21 +COc1ccccc1OCC#CCNC(=O)c1cc(C)oc1C +CCCC(=O)Nc1ccc(NC(=O)c2ccc(OC)c(OC)c2)cc1 +CCOc1ccc(S(=O)(=O)NCC(O)c2cccs2)cc1C +COC(=O)c1ccc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)cc1 +Cc1nc(C)n(CC(C)c2nc(C(C)C)nn2-c2ccccn2)n1 +N#Cc1ccc(OCC(=O)NCC(O)C2CC2)cc1 +Cc1nn(C(C)(C)C)c(=O)n1CCCOC(C)C +CC1CCCC(C)N1C(=O)c1cccc(Oc2ccccn2)c1 +O=C(NCC(O)c1ccc(C(F)(F)F)cc1)c1ccno1 +CN(CCOc1cccc(Cl)c1)S(C)(=O)=O +C=CCCC(=O)Nc1cccc(N2CCCC2=O)c1 +Nc1ccc(Br)cc1C(=O)OCC(=O)NC1CC1 +Cc1cc(S(=O)(=O)NCC(C)C)ccc1OCC(=O)N(C)C +CC(NC(=O)NCCCC1CCCC1)c1ccncc1 +COC1CCC(CC(=O)Nc2ccccc2-n2ccnn2)CC1 +COc1cccc(CS(=O)(=O)NC(c2ccccc2N)C(C)C)c1 +Cn1c(=O)n(C)c(=O)n(CC(=O)Nc2ccc3c(c2)OCO3)c1=O +N#Cc1ccccc1NC(=O)c1ccc(NC(=O)c2cccs2)cc1 +COCC(=O)N1CCC(c2nc3ccccc3cc2C(N)=O)CC1 +CCOc1ccccc1CNC(=O)CCn1cccn1 +CC(C)NC(=O)CC1OCC2CN(S(C)(=O)=O)CCC21 +O=C(c1cnn2ccccc12)N1CCC(C(=O)N2CCCC2)CC1 +Fc1ccc(CNc2nnc(-c3cccs3)o2)cc1 +Cc1cc2ncn(CC(=O)NCC(F)(F)F)c2cc1C +CCCOc1cccc(C(=O)Nc2cccc(NC(C)=O)c2)c1 +CC(C)CCNC(=O)COc1ccc2c(c1)C(=O)CC(C)(C)O2 +CN(CC(=O)NCc1cccnc1)c1ccc(N)cn1 +Cc1noc(C)c1NC(=O)N1CCC(c2nnc3ccccn23)CC1 +O=C(NCc1ccccc1)N1CCn2nc(-c3ccccn3)nc2C1 +CS(=O)(=O)N1CCCC1c1nc(C2CC2)n[nH]1 +CCCOc1nc(N2CCC(CO)CC2)ccc1N +CC(C)n1nnnc1COc1ccc(C(=O)N2CCOCC2)cc1 +O=C(CCCNC(=O)c1ccc(Cl)cc1)Nc1cccc(O)c1 +CCC1Nc2cc(OC)ccc2N(CCCO)C1=O +CCOC(=O)c1sc(NC(=O)c2ccc(Cl)cc2)nc1C +CCc1n[nH]c(SCC(=O)N2CCCc3ccccc32)n1 +CC(c1ccccc1)N(C)C(=O)Nc1nnc(C(F)(F)F)s1 +Cc1nn(-c2nc3ccccc3[nH]2)c(=O)c2ccccc12 +CCC1C(=O)NCCN1Cc1nnc(-c2ccc(C)cc2)o1 +CCc1noc(CC)c1CNC(=O)N1CCC(Cc2cnn(C)c2)C1 +CNS(=O)(=O)c1ccc(CNC(=O)NC(C)C)cc1 +CC(NC1CN(C(=O)OC(C)(C)C)CC1O)c1nccs1 +CC1CN(C(=O)Nc2cccc(F)c2F)CCO1 +Cc1ccc(N2CCC(NS(=O)(=O)c3ccccc3C)C2=O)cc1 +N#CCCN(C(=O)COc1ccccc1)C1CCCC1 +NS(=O)(=O)CCNC(=O)Cn1ccc2ccc(Cl)cc21 +O=C(CN1CCc2ccccc2C1)c1ccc2cc[nH]c2c1 +CCCN1C(=O)C(CC(=O)N2CCCC(C)C2)Sc2ncccc21 +C=CCn1c(=O)n2nc(-c3ccncc3)nc2c2c(C)c(C)sc21 +CCCNc1nnc(SCC(=O)NC2CC2)s1 +CN(C)c1nccc(N2CCCC(C(=O)N3CCCCCC3)C2)n1 +O=C1CC(c2ccc(Cl)cc2)c2ccc(O)cc2N1 +COC(=O)c1ccc(Cl)c(-c2ccc(N)nc2)c1 +CCOCCc1noc(N)c1-c1ccc(Cl)cc1 +Cc1ccc(-n2nc(CO)c(C(=O)NC3CCCC3)n2)cc1 +CC(C(=O)NCC(C)(C)c1ccc2c(c1)OCO2)n1ccnc1 +CCOC(=O)c1nc(-c2c[nH]c3ccccc23)cs1 +CCCN(CCC)C(=O)CS(=O)(=O)c1ccccc1F +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccccc1Br +O=C(Nc1ccc(Br)cc1F)c1ccnc(C2CC2)n1 +Cn1cccc1CN1CCN(C(=O)c2cccc(O)c2)CC1 +Cc1ccc(C(CNCc2ccccn2)N2CCOCC2)cc1 +COc1cccc(Cl)c1CC(=O)N1CCC(c2cnn(C)c2)CC1 +Cc1cc(C)c(-c2noc(C)n2)c(NC(=O)c2ccc(F)cc2)n1 +CC(=O)N1CCCN(C(=O)NCc2ccc3c(c2)OCO3)CC1 +Fc1ccc2c(N3CCC(n4cnnc4)CC3)ncnc2c1 +Cc1ccc(C(=O)N2CCN(Cc3cccc4cn[nH]c34)CC2)s1 +O=S(=O)(NCc1ccncc1)c1ccccc1F +C#CCNC(=O)CN1C(=O)CCOc2ccccc21 +COc1ccc(S(=O)(=O)N2CC(NC(=O)CC(C)C)C2)cc1 +COc1ccc(N)cc1CNc1ccc(C#N)cc1 +CC(C)n1cc(S(=O)(=O)N=c2ccc(-c3ccccc3)c[nH]2)cn1 +CCN(c1ccc(F)cc1)S(=O)(=O)c1ccc(C(C)=O)cc1 +CCOCCCNC(=O)C1CCN(c2cccc(F)c2C#N)CC1 +Cc1ccc2nc(C(=O)NCc3ccccc3F)cn2c1 +Cc1nn(C)cc1CNC(=O)Cn1nc(C(F)(F)F)cc1C1CC1 +Cc1ccc(-c2nn(-c3ccccc3)cc2C(=O)NCC(N)=O)cc1C +C=CCN(C)C(=O)c1ncn(-c2cccc(C)c2)n1 +CCc1ccc(S(=O)(=O)NCCc2ccoc2)s1 +CN(C)c1ccc(C(=O)Nc2ccc(Cl)cn2)cc1 +Cc1cccnc1CNC(=O)C1COc2ccc(F)cc2C1 +CCn1cc(O)c(=O)cc1CN1CC(C)OC(C)C1 +Cc1ccc(CNC(=O)CN2CCN(S(N)(=O)=O)CC2)cc1 +CCC(CC)C(=O)N(C)C(C#N)c1ccc(OC)c(OC)c1 +Cc1ccc(CNC(=O)N2CCCC(c3nncn3C)C2)s1 +COc1cc(C(=O)N(C)c2ccccc2)cc(OC)c1C +CCc1ccccc1OCCn1c(=O)oc2ccc(N)cc21 +COc1ccc(NC(=O)c2csnn2)cc1OC +CC1CCCN(C(=O)CNC(=O)Nc2ccccc2)C1 +O=C(NCC(=O)N1CCc2sccc2C1)C1CC=CC1 +Cc1nc(C)c(C#N)c(SCCOc2ccccc2)n1 +O=C(COCC1CC1)N1CCCN(c2cccnn2)CC1 +CC(=O)Nc1cccc(C(=O)OCC(=O)Nc2ccc(C)cc2)c1 +CC(NC(=O)c1cc(Cl)ccc1N)c1nncn1C +Cn1nc2n(c1=O)CCN(S(=O)(=O)c1cc(F)c(F)cc1F)C2 +Cc1nn(C)c(C)c1NC(=O)C(C)N1CCN(c2ccccc2)CC1 +CCCNc1c(CN(C)CC(C)C#N)c(C)nn1C +CC(=O)N(Cc1ccccc1)c1nc2ccccc2[nH]c1=O +Cc1nc2sc3c(c2c(=O)n1CC(=O)N1CCNCC1)CCC3 +Brc1ccn2nc(-c3cscn3)ncc12 +CNC(=O)C(C)Oc1ccc(C(=O)c2ccccc2)cc1 +Cc1ccccc1NCCC(=O)N1CCn2cccc2C1C +NC(=O)COc1ncnc2sc(-c3ccccc3)cc12 +CC(C)NC(=O)CNC(=O)c1cc(Br)cnc1N +COc1ccccc1-c1nc(C(=O)NC(C)C)cs1 +CCn1nnnc1SC(C)C(=O)Nc1ccc(F)c(Cl)c1 +Cc1ccc(NC(=O)N(C)CCc2c(C)nn(C)c2C)c(C)c1 +Cc1ccc(N2CC(C(=O)NCCNC(=O)C3CC3)CC2=O)c(F)c1 +CCn1nnc2c(Nc3ccc(C(=O)OC)cc3)ncnc21 +CCCOc1ccccc1OCC(=O)Nc1ccccc1N +Cc1cc(NC(=O)C2(C)Sc3ccccc3N(C)C2=O)n(C)n1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCC(C)(C)O)n1 +O=C(Cn1ncccc1=O)Nc1nc2ccccc2s1 +CCN1CCN(C(=O)c2c[nH]c3ccccc3c2=O)CC1 +CCN(CC)C(=O)CCC(=O)Nc1ccc2c(c1)oc1ccccc12 +CN(CCNC(=O)c1ccc(NS(C)(=O)=O)cc1)c1ccccc1 +Cc1cc(Cl)ccc1NS(=O)(=O)c1ccc(O)cc1 +CCC1Oc2ccc(C(=O)c3ccco3)cc2N(CC(N)=O)C1=O +CCc1cnc(C)nc1N1CCc2onc(-c3cccc(F)c3)c2C1 +Cc1n[nH]cc1NC(=O)Cn1ccc2ccc(Cl)cc21 +CCCN1CCn2c(nc3cc(NC(=O)c4cccs4)ccc32)C1 +NC(=O)COC(=O)c1cnn(Cc2ccccc2)c1 +CC(C)S(=O)(=O)N1CCOC(CCc2ccccc2)C1 +CCc1ccc(C(=O)Nc2cccn(Cc3ccc(F)cc3)c2=O)o1 +Cc1nc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)cs1 +Cn1cc(NC(=O)c2ccc[nH]2)cc(Br)c1=O +Cc1ccncc1NC(=O)N1CCN(c2cccc(O)c2)CC1 +CCCN1CCN(C(=O)c2cn3nc(OCC)ccc3n2)CC1 +COc1ccc(C2CC(=O)CC(Nc3nonc3N)C2)cc1 +CCNc1ccc(S(=O)(=O)N2CCCCCC2)cc1 +Cc1c(C(=O)NCc2cc(F)ccc2F)cnn1-c1ccncc1 +COCCN(CCC#N)C(=O)c1scnc1C +OCCN1CCN(Cc2csc(-c3ccccc3F)n2)CC1 +O=C(NCCn1ccnn1)NC1CCc2c1ccc(Cl)c2Cl +Cc1ccc(C2CN(C(=O)NCc3sc(C)nc3C)CCO2)o1 +CCOC(=O)c1c(C(C)=O)c(C)n(NC(=O)c2cccnc2)c1C +Cn1c(SCC(=O)NCC(F)(F)F)nnc1-c1ccccc1 +CC(=O)c1ccc(NC(=O)c2cnn(C)c2-n2cccc2)cc1 +CN1C(Cl)=Nc2ccc(C(C)(C)C)cc2S1(=O)=O +CNC(=O)COc1ccc(OC(=O)Cc2ccc(F)c(F)c2)cc1 +Cc1ccc(NC(=O)COc2ccc(S(C)(=O)=O)cc2)cc1 +CCCSc1nc(N)nc(-c2cccs2)c1C#N +CCC1COCCN1Cc1cnc(-c2ccsc2)s1 +Cc1nc(C)n(CCCNC(=O)c2cc3c(s2)CCC(C)C3)n1 +O=C(Nc1cccc(OCc2ccc(F)cc2)c1)C1CCCO1 +Cc1ccc(NC(=O)C2CC2)cc1NCC(=O)N(C)C1CCCCC1 +CCCCOCCn1c(=O)oc2cc(N)ccc21 +CN(Cc1ccccc1)c1cc(=O)n(C)c(=O)n1Cc1ccccc1 +COc1ccc(NC(=O)NC(C)c2ccc(-n3ccnc3)cc2)cc1 +Cc1ccccc1NC(=O)C1CC=CCC1C(=O)N1CCOCC1 +COC(=O)CCNC(=O)Cc1csc(-c2cccnc2)n1 +COc1ccc(CCC(=O)Nn2cnc3ccccc32)cc1 +CN(CCc1ccncc1)C(=O)Cc1coc(-c2cccs2)n1 +Cn1c(C2CCN(C(=O)CC3CCCC3)C2)nc2cccnc21 +COc1cccc(NC(=O)c2ccc3oc(=O)n(C)c3c2)c1 +O=C(Cn1nnc(-c2ccccc2)n1)Nc1c(F)cccc1F +CC(C)c1ccc(S(=O)(=O)N2CCCC(C3OCCO3)C2)cc1 +Cc1ccc(S(=O)(=O)N(C)CCCC(=O)NC(C)(C)C)cc1 +COc1ccc(C(=O)CCCC(=O)NC2CC2)cc1C +O=C(CCn1ccc2ccccc21)Nc1ccncc1 +CC1Cc2ccccc2N1C(=O)NCC1CC(=O)Nc2ccccc21 +Cn1c(=O)c2[nH]c(Cc3ccc(Cl)cc3)nc2n(C)c1=O +CC(CCCO)NC(=O)NCCc1c[nH]c2ccc(Cl)cc12 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1cccc(F)c1F +O=C(CNC(=O)Nc1cccc2c1CCCC2)NC1CC1 +Cc1ccc(C(=O)N2CCN(S(=O)(=O)N(C)C)CC2)s1 +O=C1CCCN1CCC(=O)N1CCOc2ccc(F)cc21 +Cn1ccnc1SCC(=O)NC(C1CC1)C1CC1 +C=CCNC1(C(=O)OCC)COc2cc(O)ccc21 +CC(=O)Nc1cc(C)nn1-c1nc(-c2cc3ccccc3o2)cs1 +CC(=O)NCC(=O)NCC(=O)Nc1ccc(Cl)cc1Cl +Cc1nc2c(s1)CCCC2Nc1ncccc1C(N)=O +CC(OC(=O)c1ccc(-c2cscn2)cc1)c1ccccn1 +CNC(=O)c1ccc(NC(=O)Cc2ccccc2F)cc1 +Cc1noc(C2CC3OCCC3N(c3ncccn3)C2)n1 +COCCCNc1ncnc(Nc2ccc(C)c(Cl)c2)c1N +CC(=O)N(CCc1ccccc1)CC(=O)N(C)c1ccc(F)cc1 +COc1ccc(OC)c(CNC(=O)c2n[nH]c3cccc(Cl)c23)c1 +Cn1nccc1C(=O)N1CC2CCCC2(COCc2ccccn2)C1 +O=C(c1n[nH]c(=O)c2ccccc12)N1CCCc2cc(F)ccc21 +COC(=O)c1cc(COc2ccccc2)nc(N2CCOCC2)n1 +CCOc1ccc(OCC)c(NC(=O)c2cn3cccnc3n2)c1 +Cc1ccc(CNS(=O)(=O)c2c[nH]c(-c3nnc(C)o3)c2)cc1 +COCC(=O)Nc1ccc(C(=O)OC(C)C)cc1 +CCC1(CC)Oc2cccc(N)c2N(CCC#N)C1=O +Cc1ccccc1-n1c(C)nnc1SCC(=O)OC(C)(C)C +Cc1ccc(N(C)S(=O)(=O)c2cncc(Cl)c2)cc1N(C)C +COC(=O)c1ccc(C(=O)Nc2cc(C)n[nH]2)s1 +CCc1nnc(NC(=O)CCNC(=O)c2ccccc2Cl)s1 +O=C1CCC(COC(=O)c2ccc(F)cc2F)N1 +O=C1CC2CCC(C1)N2c1ccc(F)c(Cl)c1 +CCC(=O)NCc1c(C)nc2sc(CC)nn12 +COc1ccc(F)c(NCC(=O)Nc2cc(F)ccc2F)c1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc2c(c1)CC(=O)N2 +Cc1ccc(NCC(=O)N2CC(=O)Nc3ccccc32)cc1 +CC1CN(C(=O)CCn2cnc3sccc3c2=O)CC(C)O1 +COc1cc(C#N)ccc1OCCCOc1cccc(F)c1 +O=S(=O)(Cc1ccc(F)cc1)NCC1(O)CCc2ccccc2C1 +CC(=O)NC(C(=O)Nc1ccc(C)cc1C)C(C)C +Cc1c(C(=O)Nc2ccnn2C(C)C)cnn1-c1ccccc1Cl +CCCNC(=O)c1cccc(Oc2ncc(Cl)cn2)c1 +Cn1cccc1C1CCCCCN1C(=O)c1cnns1 +O=C(CC1OCCc2ccccc21)Nc1cc(-c2cccnc2)n[nH]1 +Cc1ncnc(N2CCC(C(=O)N3CCCCC3)CC2)c1C +N#CCC1CCCOc2cc(Br)ccc21 +COc1ccc(-c2nsc(C(=O)NCC(C)C)c2N)cc1 +CCS(=O)(=O)N1CCCC(C(=O)NC2CCCCC2)C1 +CCC(CC)CNC(=O)C(N)c1ccc(Cl)cc1 +CC(C)NC(=O)CNC(=O)c1nc2c(F)cccc2s1 +COCCOC(=O)Cn1c2ccccc2c(=O)c2ccccc21 +C=CCn1nc(CNc2ccc(Cl)cc2)[nH]c1=O +COc1ccc(Cl)cc1NCCC(=O)Nc1cnn(C)c1 +COc1ccc(NC(=O)Nc2ccc(F)c(F)c2)c(OC)c1 +COC(=O)C1CCCC1NC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +COc1ccccc1CNC(=O)c1cc(-c2cccs2)[nH]n1 +O=c1c(-c2nc(-c3ccc(F)cc3)no2)c[nH]c2ccccc12 +O=C(c1ccc(Cl)cc1)C1CCN(C(=O)N2CCOCC2)CC1 +Cc1ncccc1NC(=O)c1cc2ccccc2s1 +Cn1cnnc1SCc1csc(CC(=O)Nc2ccccc2)n1 +CN(Cc1cccc2ccccc12)C(=O)c1ccc(C#N)cc1 +CCOC(=O)N1CCC(Nc2nccc(-n3nc(C)cc3C)n2)CC1 +CNC(=O)c1cccc(NC(=O)c2nc3nc(C)cc(C)n3n2)c1 +Cc1cc(C)n2nc(CC(=O)OCC3CCCCC3)nc2n1 +CS(=O)(=O)N1CCC(NC(=O)Nc2ccc(F)cc2Cl)CC1 +CCN(CCn1cccn1)C(=O)C1CCN(C(=O)C2CCCC2)CC1 +Cc1nccc(CNC(=O)c2ccc3c(c2)CCCN3)n1 +CCOCCCC(=O)N1CCC(C(=O)c2cc(F)ccc2F)CC1 +CC(C)CNC(=O)CCC(=O)N1CCN(S(C)(=O)=O)CC1 +CC(CO)CNC(=O)Cc1ccc(O)cc1Cl +COCC(C)NC(=O)Nc1cccc(Cn2ccnc2C(C)C)c1 +COCCc1noc(CC23CC4CC(CC(C4)C2)C3)n1 +Cn1cc(CC(N)=O)c2cc(Oc3ccccc3)ccc21 +COc1ccc(C)cc1NC(=O)c1nnn(Cc2ccccc2)c1N +CC(c1cccnc1)N(C)C(=O)NC1CCCCC1 +O=C(CCCc1cc(F)ccc1F)Nc1cnn(-c2ncccn2)c1 +CNc1ncnc(Nc2ccc(C(=O)OCC(C)C)cc2)c1N +Cc1ncc(CNc2ccc3[nH]nc(C(N)=O)c3c2)s1 +Cc1nc(C2CCCCCN2C(=O)Nc2cccc(F)c2)no1 +NC(=O)COC1COC2C(NC(=O)C3CCCCC3)COC12 +CCOc1cccc(C(C)NC(=O)NCc2csc(C)n2)c1 +NC(=O)NCc1ccc(NC(=O)c2ccc(Cn3cccn3)cc2)cc1 +O=C(CCNS(=O)(=O)c1cccc(Cl)c1)NC1CC1 +N#CCCN(Cc1ccco1)C(=O)Cn1nc2n(c1=O)CCCCC2 +COc1cc(NC(=O)CCC2CCCC2)cc(OC)c1OC +COc1ccc(CNC(=O)c2cc(C)c(C)c(S(N)(=O)=O)c2)cc1 +O=C(CSc1nc(C2CCCO2)n[nH]1)Nc1ccc(F)cc1 +Cc1ccc(C(C)NS(=O)(=O)c2ccc(C(N)=O)cc2)cc1F +Nc1ccc2c(c1)N(Cc1ccccc1)C(=O)C(c1ccccc1)O2 +Cc1nc(NC(=O)c2n[nH]c3ccccc23)sc1C +Cc1ccc(OCc2ncc(C(=O)NC(C)C)c(N)n2)cc1 +CC(C(=O)N1CCC(N2CCNC2=O)CC1)n1cnc2ccccc21 +CC(C)Cc1nnc(NC(=O)N(C)Cc2ccc(F)cc2)s1 +CC(C)(C)C(NC(=O)Nc1ccc2nc(C3CC3)oc2c1)C(N)=O +COc1ncccc1-c1nc(N)nc(Nc2ccc(C)cc2)n1 +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)c1ccco1 +CC(c1ccc(F)cc1)N(C)C(=O)NCCNS(C)(=O)=O +O=C(c1ccc(Cn2cccn2)o1)N1CCC2(CCCCC2)C1 +COc1c(N)cc(C(=O)c2cccs2)c(O)c1OC +COCC1CC2(CCN(C(=O)Cc3ccccc3F)CC2)CO1 +COc1ccccc1NC(=O)c1ccc(F)c(F)c1F +CNC(=O)C(O)c1ccc2c(c1)nc(C)n2C1CC1 +COc1ccc(-c2nnc(NC(=O)Cc3ccccc3)o2)cc1OC +Cc1nnc(CSc2nnc(-c3ccco3)n2C2CCCCC2)o1 +C=CCOc1cc(C(=O)NCCC)cc2occc12 +Cc1noc(COCC(=O)Nc2cnn(C)c2)n1 +Cc1cccc(S(=O)(=O)C(C)c2nc(C(C)(C)C)no2)c1 +Cc1c(N)cccc1NC(=O)COCc1ccccc1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccsc1 +NS(=O)(=O)c1ccc(NC(=O)N2CCCC2CO)cc1 +COc1ccc(C(=O)N2CCC(=O)CC2)cc1OC +O=C(c1cc(-n2cccn2)ccn1)N(CC1CCCO1)C1CCCC1 +Cc1nc2ccc(NC(=O)NCCCOCC3CCCO3)cc2s1 +Cc1ccc(Cn2c(C(=O)NCc3ccccn3)cc3occc32)cc1 +Nc1nc2cc(-c3ccc4ccccc4n3)ccn2n1 +Cc1cc(C)nc(SCC(=O)NCc2ccco2)n1 +CCOc1ccc(C(=O)NC(C)C(=O)N2CCCCC2)cc1OCC +N#CC1(NC(=O)c2cc(Cl)c3c(c2)OCCO3)CCCCC1 +CCSc1nnnn1-c1c(C)n(C)n(-c2ccccc2)c1=O +CNS(=O)(=O)c1ccc(C)c(NC(=O)c2cn3cccnc3n2)c1 +Cn1c(=O)c2c(ncn2CCSc2ccc(O)cc2)n(C)c1=O +Cc1nn(Cc2cc(=O)n3cccc(C)c3n2)c(=O)c(C#N)c1C +Cc1cccc(N2CCN(CC(=O)c3cc(C)n(C)c3C)CC2C)c1 +O=C(c1cn2c3c(cc(Br)cc3c1=O)CC2)N1CCCC1 +COCCN(Cc1ccco1)C(=O)Nc1cccc(Cl)c1F +CC(=O)c1ccc(F)cc1OC(C)C(=O)N(C)C +COC(=O)CN(Cc1cccc(-n2cccn2)c1)C1CCCC1 +CCCc1cc(Br)c2c(c1)N(C)C(=O)CO2 +O=c1c2oc3ccccc3c2ncn1Cc1nnc(-c2ccccc2)o1 +COC(=O)C1(c2ccccc2)CCN(S(N)(=O)=O)CC1 +Cc1nc(NCCO)c2c(-c3ccccc3)csc2n1 +Cc1ccccc1C(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1 +C=CCn1c(C)nnc1SC1CCN(C)C1=O +CN(Cc1ccccc1)c1nc2[nH]ncc2c(=O)[nH]1 +CCN(CCC(=O)Nc1cccc(N)c1)c1ccccc1C +CCOc1ccc(NC(=O)CNC(=O)Cc2cccc(F)c2)c(C)c1 +CSc1nnc2n(CCC(C)C)c(=O)c3ccccc3n12 +COC(=O)CCn1c(CC#N)nc2ccc(F)cc21 +Cc1ccc(C)c(C(=O)Cn2cnc3sc(C)cc3c2=O)c1 +CC(C)N1CC(C(=O)N(C)CC(=O)NC(C)(C)C)CC1=O +CCOc1cc(-c2nnc3cccc(C)n23)ccc1N +CCOC(C)c1noc(CNc2cc(NC(C)=O)ccc2Cl)n1 +CN(C)c1ccc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)cc1 +O=C(Nc1ccc2c(c1)OCC(=O)N2Cc1ccccc1)c1ccco1 +CCC(=O)c1cc2c(cc1NC(=O)c1ccc(C)cc1)OCCO2 +O=C(COc1cccc(Oc2ccccn2)c1)Nc1cccnc1 +CCN(c1ccccc1)c1nc2nonc2nc1N(C)C +CC(=O)c1ccc(S(=O)(=O)N(Cc2cccs2)C2CC2)cc1 +CC(C)COC1CCN(C(=O)c2ccc(OCC(F)F)nc2)C1 +N#Cc1ccc(C(=O)OCC(=O)c2ccc3c(c2)OCCO3)cc1 +CC(=O)Nc1cccc(Oc2ccc(C#N)c(C#N)c2)c1 +CCS(=O)(=O)c1ccc(C(=O)Nc2cc(C)on2)cc1 +Cc1cc(S(=O)(=O)NCC(C)(C)c2ccncc2)c(C)s1 +Cc1cc(C(=O)N2CC(C(N)=O)CCC2C)c2ccccc2n1 +C#CCN1CCC(C(=O)NCc2coc(-c3cccs3)n2)CC1 +CCC(C)(C)NC(=O)CN1CCOCC1CC(C)C +CN1CC2CN(Cc3ccc(S(C)(=O)=O)cc3)CCN2C1=O +CSc1ccc2nc(N3CCN(C(C)=O)CC3)sc2c1 +O=C(CCCc1nc2ccccc2s1)Nc1nc[nH]n1 +C=C(C)CSc1nc2ccccc2c(=O)n1CCCO +O=C(COC(=O)c1cnccn1)c1ccc(Cl)cc1 +CCCc1nnc(NC(=O)Cc2ccc(Cl)cc2)s1 +CCSc1ccc(C(=O)Nc2ccccc2C(N)=O)cn1 +Cn1nc2c(c1NC(=O)COCC(F)(F)F)CCC2 +CSc1ccc(CNC(=O)NCC2CCC2)cc1 +CCOc1ccc(-c2cc(CO)c(C)o2)c(OCC)c1 +Oc1ccc(C2NCCc3c(F)cc(F)cc32)c(F)c1 +Cn1c(=O)ccn(CC(=O)OCC#Cc2ccccc2)c1=O +Cc1ccsc1C=c1sc2nc(-c3ccncc3)nn2c1=O +CC(C)C(=O)Nc1cc(F)cc(N2CCCC2)c1 +O=C(CSc1nc(=O)[nH]c2c1CCC2)Nc1ccccc1Cl +CC(C#N)NS(=O)(=O)Cc1ccccc1Cl +O=C(CSc1nnnn1Cc1ccccc1)NC1CCCCC1 +COc1cc(OC)c(C(=O)c2cccs2)cc1N +CNC(=O)C1CCN(C(=O)c2cnn(C)c2-n2cccc2)CC1 +CC(C)c1ccsc1C(=O)OCC1CC(=O)N(C2CC2)C1 +O=C(c1cccnc1)N1CCN(C(=O)c2ccccc2F)CC1 +COCCOC(=O)C(C#N)c1nc2ccccc2nc1N1CCCC1 +O=C(c1ccccc1F)N1CC(c2nc(-c3ncccn3)no2)C1 +Cc1ccc(Nc2ncnc(NCCN3CCOCC3)c2N)nc1 +N#Cc1ccc(NC(=O)CN2CCCc3ccccc32)cc1 +Cc1ccc(C(=O)CCC(=O)Oc2ccc3c(c2)OCO3)s1 +COc1cccc(OCC(=O)N2CC(C)OCC2C)c1 +CC1CC(C)CN(C(=O)Cn2ccc(=O)c3sccc32)C1 +CC(CCCO)NC(=O)NC(C)c1cccc(Cl)c1 +COc1cc2nnn(Cc3ccccc3C#N)c2cc1OC +CC(C)C(=O)NCCNC(=O)c1ccc(Cl)cc1F +Cc1c(C(=O)Nc2ccc(C#N)cc2)nnn1-c1cccc(Cl)c1 +CCN(CC(=O)Nc1cc(C)on1)S(=O)(=O)c1ccc(C)cc1 +CS(=O)(=O)c1ccc(NCCN2CCOCC2)cc1 +CS(=O)(=O)c1ccc(NC(=O)C2(c3cccc(Cl)c3)CC2)cc1 +COC(C)C(=O)Oc1ccc(N(C)C(=O)c2ccc(C)cc2)cc1 +CCC(=O)Nc1ccc2oc(-c3cccs3)nc2c1 +C=CCNc1ncc(Br)cc1Br +O=S(=O)(NCC1CC1)c1ccc(Cl)c2ncccc12 +Cc1nc(SC(C)C(N)=O)c2c3c(sc2n1)CCCC3 +C=CCN(C)C(=O)c1coc(COc2cccc3cnccc23)n1 +CCOC(=O)C1CCN(C(=O)c2ccc(O)c(Cl)c2)CC1 +Cc1ccccc1C(C)NC(=O)NCCNC(=O)OC(C)(C)C +CCOCCNC(=O)c1ccc(CNC(N)=O)cc1 +COc1ccc(NC(=O)C(C)NC(=O)Nc2ccccc2)cc1F +Cc1ccccc1NC(=O)c1sc2nc(C3CC3)nc(C)c2c1N +CCCNC(=O)CS(=O)(=O)c1nnc(-c2ccccc2)n1CC +Cc1cc(C(=O)Cn2cncn2)c(C)n1-c1nccs1 +Cc1cccc(NC(=O)N2CCN(C(=O)Cn3cnnn3)CC2)c1 +O=C(c1csnn1)N1CCc2onc(-c3cccc(F)c3)c2C1 +COc1ccccc1C(=O)CNC(=O)c1ccccc1 +CCc1ccc(CNC(=O)c2cnn3c4c(cnc23)CC(C)CC4)cc1 +COCCN(Cc1ccsc1)C(=O)Nc1ccccc1C +OCc1nc2cccnc2n1Cc1cccc(F)c1 +Cc1noc(-c2ccc(C(=O)N(C)C3CCCC(C)C3)cc2)n1 +O=C(NCCc1cccc(-c2ccsc2)c1)c1n[nH]c2ncccc12 +CCCCNC(=O)Cn1cc(N)cc1C(=O)OC +COc1cccc(C2CCN2C(=O)c2ccc3c(c2)ncn3C)c1 +CCc1c(C#N)nnn1-c1ccc(C)c(Br)c1 +Cc1ccc(CC(=O)NCCc2nc3ccccc3s2)s1 +CC(C)(CNC(=O)CNS(C)(=O)=O)c1cccc(Cl)c1 +COc1ccc2c(ccn2CC(=O)Nc2cccc(-c3cn[nH]c3)c2)c1 +COc1cc(Cl)c(C)cc1NC(=O)c1cnccn1 +Cc1noc(C)c1CCCNC(=O)c1ccc(-c2cc[nH]n2)nc1 +COc1ccc2c(c1)OCC(C(=O)OCCc1c(C)n[nH]c1C)C2 +O=C(NCc1ccc2c(c1)OCO2)N1CCCC2(C1)OCCO2 +CCOC(=O)N1CCC(NC(=O)Cc2ccc(Cl)cc2)CC1 +NC(=O)c1cccc2nc(C3CCN(C(=O)C4CCCCC4)C3)[nH]c12 +COc1cc(OC)cc(C(=O)Nc2ccc(C)c(-n3cnnn3)c2)c1 +CC(C)(C#N)C(=O)Nc1ccc2oc(=O)ccc2c1 +CCOc1nc(N(CC(F)(F)F)C(C)C)ccc1N +CCNC(=O)CNC(=O)Nc1cccn(Cc2ccccc2)c1=O +Fc1cc(CN2CCOC(Cn3cncn3)C2)c2ncccc2c1 +CCOC(=O)CNC(=O)COc1ccc(F)cc1 +CC(=O)c1cc2c(cc1NC(=O)c1ccc(Cl)cc1)OCCO2 +COCC(=O)NC(c1ccc(OC)cc1)c1nccn1C +COc1ccccc1OC(=O)C1CCN(c2cnccn2)CC1 +CC(=O)c1c[nH]c(C(=O)NCc2ccc(Cn3ccccc3=O)cc2)c1 +Cn1cnc(CNC(=O)NCC(C)(C)c2cccc(F)c2)n1 +CN1CC(C(=O)Nc2ccc(OC(F)F)c(F)c2)CC1=O +COc1cccc(C(C)NC(=O)c2ccc3c(c2)OCO3)c1 +Cc1cccc(-n2ccnc2SCCNS(C)(=O)=O)c1C +O=C(CN1CCOCC1)Nc1cccc(C(=O)N2CCCC2)c1 +CCN(C(=O)CCC(=O)OC)c1ccc(Br)cn1 +COc1ccc(CCNC(=O)c2ccc(F)c(F)c2)cc1 +CC(C)NC(=O)CCNC(=O)NC1CCC(O)CC1 +NC(=O)CCSc1nnc(-c2ccco2)n1C1CCCCC1 +CCC(Cc1ccccc1)OC(=O)c1ncn(-c2ccccc2)n1 +Cc1cc(C)nc(N2CCC(C(=O)N=c3[nH]cc[nH]3)CC2)n1 +CCc1nc(CC(=O)N2CCN(C3CCCC3O)CC2)cs1 +CNC(=O)c1sc(Nc2cccc(Cl)c2)nc1C +O=C(Nc1ccc(Oc2cccc3[nH]ccc23)nc1)c1ccco1 +c1ccc(Cc2noc(CSc3nnc(-c4ccc[nH]4)o3)n2)cc1 +Cc1oc2c(C)c3oc(=O)cc(C)c3cc2c1COCCO +Cc1ccc(C(=O)CCC(=O)OC(C)c2ccccn2)s1 +Cc1cn(C)nc1C(=O)Nc1nc2c(s1)CN(C)CC2 +CCN(Cc1ccccc1)C(=O)Nc1cc(S(C)(=O)=O)ccc1C +c1ccc(CCNCc2cc3ccccc3o2)nc1 +Cc1noc(COCC(=O)N2CCC(OCC(C)C)CC2)n1 +c1cc2c(cc1OCCN1CCN(CC3CCOCO3)CC1)CCC2 +Cc1nc(CNS(=O)(=O)c2ccc3c(c2)OCCCO3)cs1 +Brc1cccc2[nH]c(-c3cscn3)cc12 +CC(=O)NCC(=O)Nc1ccc(CN2CCCC2=O)cc1 +Cc1c(NC(=O)NC(CO)c2ccco2)cccc1OC1CCCC1 +CCN(CC)C(=O)CCC(=O)NCc1nnc2n1CCCCC2 +CC(C)C(=O)Nc1ccc(C(=O)NC(C#N)C(C)(C)C)cc1 +CCc1onc(C)c1NC(=O)c1ccccc1SCC1CCCO1 +COc1cc(C(=O)Nc2c(F)cccc2F)cc(OC)c1C +Cn1cnnc1-c1ccccc1NC(=O)c1ccc(Cl)cc1 +COCC1CCN(C(=O)C2CCCN(C(=O)C(C)(C)C)C2)CC1 +CC(=O)Nc1ccc(S(=O)(=O)N(C)CC(F)(F)F)cc1 +C=CCn1c(=O)n(CC=C)c(=O)n(Cc2cc(C)on2)c1=O +COc1ccc(-n2nnnc2SCCO)cc1 +Cc1ccc(NC(CO)c2cc(C)sc2C)cc1 +Cc1cccc(NC(=O)C(C)(C)C)c1NC(=O)NC(C)C +CCn1nnc2c1CCN(Cc1ccoc1)C2COCC1CC1 +O=C(NCc1ccccc1)NCC1(c2ccc(F)cc2)CC1 +O=C(Nc1cccc(OCc2cscn2)c1)C1CC=CC1 +CCOCC(=O)Nc1cc(C(F)(F)F)ccc1N1CCOCC1 +Cc1[nH]ccc1C(=O)N1CCCC1CC(=O)c1ccccc1 +COc1ccc(NC(C)=O)c(NC(=O)c2n[nH]c3ccccc23)c1 +O=c1nc2n(CC(O)C(O)C(O)CO)c3ccccc3cc-2c(=O)[nH]1 +Cn1c(=O)oc2cc(NCc3cnc(C(C)(C)C)s3)ccc21 +O=C(Cc1cccs1)NC1CCN(C(=O)c2ccco2)CC1 +Cc1nc(C(=O)NC(C)Cn2cccn2)cs1 +COc1cccc2sc(NC(=O)CCC(=O)c3ccccc3)nc12 +O=C(NC1CCC(O)CC1)c1ccc(COc2ccc(F)cc2)o1 +Cc1ccc(CN2CCC3C2CCN3c2ncccn2)s1 +CS(=O)(=O)Nc1cccc(NC(=O)c2cnccn2)c1 +Cn1c(=O)c2c(ncn2CC(=O)Nc2ccc(F)c(F)c2)n(C)c1=O +Cc1onc(-c2ccccc2)c1C(=O)NCCc1cccc(F)c1 +CCC(=O)N1C2CCC1CN(CCc1ccccc1)C2 +CCCn1ncc(-c2cn(CCc3c(C)n[nH]c3C)nn2)c1C +Cc1cnc(NC(=O)c2ccc(F)c(N)c2)s1 +COCCN1CN=C(Nc2nc3ccccc3s2)NC1 +O=C(CCC(=O)c1ccc(F)cc1F)Nc1cccc(F)c1 +Cc1ncsc1CNC(=O)C(C)(N)c1ccccc1 +CC(C)c1ccc(C2CCCN2C(=O)C2CCC(=O)NC2)cc1 +CNC(=O)NCC(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +CCCc1nnc(NC(=O)c2cc(-c3ccc(C)cc3O)n[nH]2)s1 +CC(C)(C)C(NC(=O)c1cn(-c2ccccc2Cl)nn1)C(N)=O +CCC(=O)Nc1c(C)noc1C=Cc1ccc(S(=O)(=O)NC)cc1 +Cn1ccc2c(C(=O)OCCc3cccnc3)cccc21 +CCC(=O)N1CCC2(CC1)CC(CC(=O)N(C)C)c1ccccc12 +CC(=O)Oc1cc2oc(=O)cc(C)c2cc1OC(C)=O +Cc1cc(C(=O)NCCCNC(=O)c2cccs2)no1 +Cc1cccc(-c2n[nH]cc2-c2ccc3nccnc3c2)n1 +COC1CCCC1OC(=O)c1cc(C)ccc1F +C=CCNC(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 +Cc1oc(-c2ccco2)nc1Cn1cccc(C(F)(F)F)c1=O +COc1ccc(CNS(=O)(=O)c2cc(C#N)ccc2C)c(OC)c1 +CC(C)c1nnc(NC(=O)CNC(=O)c2ccccc2)s1 +COCc1ccccc1CNC(=O)c1ccc(-c2nc(C)no2)cc1 +O=C(Cc1ccc(-n2cccc2)cc1)NCCNC(=O)c1ccccc1 +CC1CCC(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)CC1 +COc1ccc(S(=O)(=O)Nc2cccnc2)cc1F +CCCNS(=O)(=O)c1ccc(NC(=O)N(CC)CC)cc1 +CC(C)(C)C(=O)NCCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +Cc1ccccc1Cn1cccc(C(=O)Nc2cccnc2)c1=O +N#CC1(C(=O)NCc2nc3ccc(F)cc3[nH]2)CCCCC1 +C=CCSc1ccccc1NC(=O)CSc1nncn1C +Cc1ccc2c(c1)NC1(CCCCCC1)C(=O)N2CCO +CCn1nc(C)cc1NC(=O)CN1C(=O)CC(C)(C)c2ccccc21 +O=C(CCn1ccc2ccc(F)cc21)NCc1ccncc1 +Cc1nnc(NC(=O)COc2ccc(-c3ccccc3)cc2)s1 +O=C(COC(=O)CCc1ccccc1)Nc1cccc(F)c1 +CCOC(=O)c1cc(N)ccc1NC(=O)OC(C)(C)C +Cc1ccc(S(=O)(=O)N(C)Cc2cn3ccccc3n2)cc1 +CCCC(NC(N)=O)C(=O)Nc1c2c(nn1C)CCC2 +Cc1ccc(=O)n(CC(=O)Nc2c(C)cccc2Cl)n1 +Cc1ccc(C)c(Cn2c(=O)n(C)c(=O)c3sccc32)c1 +C=C(C)CSc1nnc(Cc2ccccc2F)o1 +CC(C(=O)Nc1cccnc1N1CCOCC1)c1cccs1 +CCOC(=O)NCCc1ccc(S(=O)(=O)N2CCOCC2)cc1 +COc1ccc(C(=O)CSc2nnc(C3CC3)o2)cc1F +CCOc1c(O)ccc2c1C(c1ccccc1C#N)NCC2 +CCNC(=O)CN1CCN(c2ccc(OC)c(OC)c2)C1=O +Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)Cc1ccccc1 +Cc1cccc(C)c1NC(=O)CSc1nnc(-c2ccoc2C)o1 +Cc1ccc(S(=O)(=O)NCC23C=CC(CC(=O)C2)O3)cc1 +CC(CNC(=O)c1ccc(=O)n(C)n1)N1CCOCC1 +CC(CCCO)NC(=O)Nc1ccccc1C(C)(C)C +O=c1ccc(C2NCCc3cc4ccccc4cc32)n[nH]1 +CC(CNC(C(N)=O)c1ccc(F)cc1)Oc1ccccc1 +CSc1nnc(CSc2nc(-c3ccccc3F)n[nH]2)s1 +CCCCNC(=O)Cc1noc2c(N)cc(F)cc12 +CC(=O)N1CCc2cc(C(=O)NC3CCCC3)ccc21 +CC(C)(O)c1cc2nc3ccccc3nc2n1CCO +Cc1nn(C)c2cnn(C(C)C(=O)N3CCN(C)CC3)c12 +CN(Cc1ccccc1Cl)C(=O)Nc1cccnc1 +O=C(NCc1cccnc1Oc1ccccc1)c1cnn2cccnc12 +O=C(Cc1n[nH]c(-c2cccnc2)n1)NCCc1ccccc1 +COc1cc(C(C)=O)ccc1OC(=O)C1COc2ccc(F)cc2C1 +Cc1cccc2nc(C(=O)OC(C(=O)N(C)C)c3ccccc3)cn12 +O=C(CCc1cccnc1)N1CCC2(CCN2c2ncccn2)C1 +O=C(NCCOc1cccnc1)N1CCOCC1C1CC1 +Cn1c(=O)c2ncn(CC(=O)Nc3cccc(O)c3)c2n(C)c1=O +Cc1ccn(-c2ccc(NC(=O)c3cc(-c4ccccc4)on3)cc2)n1 +N#Cc1ccc(NCC(=O)Nc2ccc3c(c2)CCC3)cc1 +CCCS(=O)(=O)NCC(C)(C)c1ccccc1 +O=C(Nc1nc(C(=O)Nc2ccccc2Cl)co1)c1cnccn1 +Cc1noc(COC(=O)c2ccc(Cl)cc2N2CCCC2=O)n1 +CCCCCS(=O)(=O)N1CCC2C(CCC(=O)N2C2CC2)C1 +CCCOC(=O)N1CCC(c2ccc3c(c2)OCO3)C(O)C1 +COc1cccc(C2CCCCN2C(=O)c2sc(C)nc2C)c1 +O=C(Nc1ccc2cc[nH]c2c1)C1CCCN(c2ncccn2)C1 +COC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)c2cnn(C)c2)c1C +COc1cc(CC(=O)NCC2CN3CCCCC3CO2)ccc1C +O=C1CC(c2ccccc2)N(Cc2c[nH]nc2-c2ccccc2)CCN1 +Nc1cccc(NC(=O)CSc2nc3ccccc3[nH]2)c1 +CCc1cc(OCn2nc(C)c(N)c2C)ccc1Cl +O=C(Cn1c(=O)cnc2ccccc21)Nc1cccc2ccccc12 +CCS(=O)(=O)NC(c1ccccc1C(F)(F)F)C(F)(F)F +O=S(=O)(c1cccs1)N(Cc1ccco1)CC1CCCO1 +CCCNC(=O)c1nnn(-c2ccc(Cl)cc2)c1C +CCOc1ccccc1C(=O)NCC(=O)N(C)Cc1ccccc1 +CN(CCc1ccccn1)C(=O)c1csc(-c2cnn(C)c2)n1 +CCOc1ccc2nc(-c3nccn3Cc3cc(C)on3)ccc2c1 +COc1ccc(OCC(=O)NC2CCc3c(O)cccc32)cc1 +CC(NC(=O)CN(C)C(=O)c1ccco1)c1cc2ccccc2o1 +CCN(CC(=O)NCc1ccc(F)cc1)C(=O)c1ccccc1 +CCC(C)NC(=O)C(C)NC(=O)Nc1ccc(F)c(C#N)c1 +COCCn1cc(NCc2cc(Br)ccc2F)cn1 +COc1ccc(C(=O)NC2c3ccccc3CC2C)cc1OC +Cn1cc(C(=O)C(C#N)c2ccc(F)cn2)c(C(C)(C)C)n1 +COc1ccc(CNc2c(C)cccc2O)cc1F +CCc1onc(C)c1NC(=O)NC(C)COC1CCOC1 +NC(=O)N1CCCC(C(=O)Oc2ccc3oc4c(c3c2)CCCC4)C1 +CCS(=O)(=O)N1CCCC(Cn2nnc(-c3ccccn3)n2)C1 +COc1ccc(COC2CN(C(=O)c3ccccc3F)C2)cc1F +Cc1cccnc1CCNC(=O)C1CC(=O)N(CC(C)C)C1 +Cc1noc(C)c1COc1ccccc1C(=O)N1CCOC(C)C1 +C=CCNC(=O)N1CCN(CCNC(=O)c2ccccc2F)CC1 +Cc1cc(-c2ccccc2)n2[nH]c(=O)c(Br)c2n1 +CC(=O)NC(C)C(=O)Nc1ccccc1OCC(F)(F)F +COc1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)c2)cc1 +Cc1cc(NC(=O)c2ccc3ncsc3c2)n(-c2ccccc2)n1 +Cn1ncc(NC2CCN(c3c(F)cccc3F)C2)c(Cl)c1=O +CC(C)NC(=O)CN1CCN(c2nccs2)CC1 +O=C(OCC(=O)N1CCCC1)c1ccc(F)cc1F +Cc1ccc(CNC(=O)c2c(-c3ccncc3)noc2C)o1 +CCCC(C)(C)NS(=O)(=O)c1ccc(C)s1 +Cc1ccc2cccc(-c3nc(C4CC4)no3)c2n1 +CCOC(=O)N1CCC(NC(=O)NC(c2ccccc2)C(C)C)CC1 +Cc1nc(C2CCCN(c3c(C)c(C)nc4ncnn34)C2)no1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)N1CCCC(C)C1 +CCC(CC)NC(=O)c1cccnc1SCc1c(C)noc1C +Cc1ccc(NC(=O)NCc2ccccc2S(=O)(=O)N(C)C)cc1 +CC(C)(C)OC(=O)N1CCCN(C(=O)Nc2ccncc2)CC1 +C=CCOc1c(Br)cc(CNc2ncn[nH]2)cc1OC +CC(=O)N1CCN(C(C(=O)NCC2CCCO2)C2CCCC2)CC1 +CN(Cc1cccc(F)c1)C(=O)c1ccc(N2CCCC2=O)cc1 +COc1ccc(C(=O)NCCS(=O)(=O)N2CCCCC2)cc1 +O=C(CCC1CCCO1)NCc1ccnc(Oc2ccc(F)cc2)c1 +Cc1cc(NC(=O)CCn2cnc3c(C)cccc3c2=O)[nH]n1 +Cn1cnc2cc(C(=O)Nc3ccc(F)c(C#N)c3)ccc21 +COC(=O)c1ccccc1NC(=O)c1nccc2cccc(N)c12 +Cc1noc(-c2cccn(Cc3noc(-c4ccccc4C)n3)c2=O)n1 +CCC(C(=O)Nc1cc(NC(C)=O)ccc1F)c1ccccc1 +COc1ccc2c(C(=O)NCCc3ccc(C)o3)cc(=O)oc2c1 +Cc1c(C(=O)OCC2CCOc3ccccc32)cnn1C +COCC1(c2nc(C3CCOCC3)nn2C(C)(C)C)CC1 +Cc1ccccc1C1CN(Cc2cnc3ncccn23)C(C)CO1 +Nc1ccc(Br)c2[nH]cc(C3CC3)c12 +CCC(C)C(C)(O)CNC(=O)c1cccc(-c2nnc(C)o2)c1 +OCCc1nc2cccc(F)c2n1C1(c2ccccc2)CC1 +CC(C)CC1COCCN1S(=O)(=O)c1c(F)cccc1F +COc1cc(Br)c2c(c1OC)CCO2 +CSc1ccccc1NC(=O)CSc1nncn1C(C)C +Cc1cc(C)cc(C(=O)NCC2(C(N)=O)CCOCC2)c1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)c1ccc(C(C)C)cc1 +CCOC(=O)c1ccsc1NC(=O)c1cc(Cl)ccn1 +Cc1ccc(-c2ocnc2C(=O)N2CCC3(CCOC3)C2)cc1 +CC1CC1CNC(=O)CNC(=O)NCc1ccco1 +CCN(Cc1ccccc1NC(=O)NCc1cccnc1)C(C)=O +O=C(Cc1ccc2c(c1)OCC2)NCCCc1nnc2ccccn12 +Cc1ccc(C(=O)NCc2cn(-c3ccccc3)nn2)c(C)c1 +CN(CC(=O)N1CCNCC1)C(=O)c1ccc(Cl)c(Cl)c1 +COc1ccccc1CN(C)S(=O)(=O)c1ccc(N)cc1 +OCCNc1nc(-c2ccncc2)nc2ccccc12 +COc1c(F)cc(NC(=O)NC(C)(C)c2ncc(C)s2)cc1F +Cc1ccccc1C(C)(C)C(=O)NCc1ccccc1Cn1cncn1 +C=CCn1c(C)cn2c3c(=O)n(CCC(C)C)c(=O)n(C)c3nc12 +O=C(Cn1cnnn1)OCc1ccccc1Oc1ccccc1 +CC(C)COc1cncc(N2CCN(c3cc(C#N)ccn3)CC2)n1 +O=C(CCn1c(=O)oc2ccccc21)Nc1ccc2[nH]c(=O)[nH]c2c1 +O=C(CCC1CCCO1)N(Cc1ccccc1)c1ccccc1 +COc1ccc(-c2csc(NC(=O)NC3CCCC3)n2)cc1OC +COc1ncccc1CNC(=O)N(C)Cc1cnn(C)c1 +N#Cc1cccc(NC(=O)C(c2ccccc2)N2CCCCC2=O)c1 +Cc1ccc(OCC(=O)N2CCN(Cc3ccccc3F)CC2)cc1 +CCCC1CN(C(=O)c2ccc(N(CC)CC)cc2)CCO1 +COc1ccc2c(ccn2CC(=O)NCc2c(C)nn(C)c2C)c1 +CC(C)C(=O)c1ccccc1NC(=O)COc1ccccc1 +CCc1nc(C)cn1S(=O)(=O)c1cc(OC)ccc1OC +Cc1ccc(CN(C)C(=O)COc2ccc(Cl)c(C)c2)o1 +COc1cc2ncc(=O)n(Cc3ccn(C(C)C)n3)c2cc1OC +O=C(NCCCc1nc2ccccc2[nH]1)c1cc(-c2cccnc2)n[nH]1 +CC(C)n1ncc2c(C(=O)Nc3nncs3)c3c(nc21)CCC3 +CCC(C)C(C)NC(=O)c1ccc(OCC(F)F)nc1 +CCCCNC(=O)c1cc(S(=O)(=O)NCC)ccc1C +CN(Cc1ccco1)C(=O)Cn1c(=O)c(C#N)cn(C2CC2)c1=O +O=C(c1cc2ccccc2[nH]1)N1CCCC(O)(CO)C1 +Cc1ccc(C(=O)Nn2cnc3ccccc3c2=O)o1 +CCc1ccc(C(=O)N2CCN(c3nnc4cccc(C)n34)CC2)cc1 +CCOCC1CN(C(=O)c2cnc(C)cn2)Cc2ccnn2C1 +O=C(NC1C2CCOC2C12CCC2)c1ccc(-n2ccnn2)cc1 +COc1ccc(S(=O)(=O)NCc2ccncc2)cc1C(C)(C)C +CCC(C)Nc1nnc(SC2CCCCNC2=O)s1 +COc1ccccc1OCC(=O)Nc1ccccc1Br +Cc1ccccc1C1CC1C(=O)N(CC(N)=O)C(C)C +Cc1oncc1C(=O)Nc1ccc(NC(=O)CCC2CCCC2)cc1 +NC(=O)Cc1ccc(C(=O)Cn2cnc3ccsc3c2=O)s1 +Cc1cccc(C(C)C)c1NC(=O)c1cc(C2CC2)nc2onc(C)c12 +COCc1cccc(C(=O)OCc2cc(C#N)ccc2F)c1 +CCc1ccccc1OCC(=O)Nc1ccnn1C(C)C +CC(C)n1cc(S(=O)(=O)N=c2[nH]c3c(s2)CCCC3)cn1 +CC(C)(CNC(=O)CSc1ncccc1Cl)N1CCOCC1 +O=C1CC(c2nc(C3CCOC3)no2)CN1C1CCCCCC1 +NC(=O)COc1ccc(CNCC(F)(F)F)cc1 +O=C(NCc1ccc(-n2cncn2)nc1)NCC1CCCO1 +Cc1cc(NC(=O)CCc2cnn(-c3ccccc3)c2)n(C)n1 +CCOC(CC)C(=O)Nc1ccc(OC)c(N2CCCCC2=O)c1 +CCN(Cc1ccoc1)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +C=CCN1C(=O)C(Cc2ccc(OC)cc2)Oc2cc(O)ccc21 +CC1CCN(C(=O)CN(C)c2ncnc3[nH]cnc23)CC1 +NC(=O)CNC(=O)C(Sc1ccccc1Cl)c1ccccc1 +Cc1ccc(S(=O)(=O)NCCC(=O)N2CCC2)cc1C +CCC(CC)N(C)C(=O)Nc1ccccc1-n1cccn1 +CCOc1ccc(NC(=O)CNC(=O)c2cccs2)cc1 +COC(=O)c1cccc(CCNC(=O)Nc2cnc(C3CC3)nc2)c1 +FC(F)(F)c1nnc2sc(COc3ccccc3Cl)nn12 +O=C(Cc1csc(N2CCCC2=O)n1)NCCC1CC2CCC1C2 +CCn1cc(NS(=O)(=O)c2ccc(O)c(N)c2)cn1 +O=C(NCc1ccccc1-n1cccn1)c1cc(=O)c2ccccc2[nH]1 +CCCCn1nc(C2CCCC2)nc1-c1cnc(C(C)C)[nH]c1=O +COC(C)C(=O)N(C)Cc1ccccc1N1CCCC1 +COc1cc(N)cc(C(=O)N(C)Cc2ccccc2)c1OC +O=c1[nH]c2c(c(=O)n1CCO)C1(CCCCC1)Cc1ccccc1-2 +CC(Sc1nnc(-c2ccccc2)n1C)c1nc(C2CC2)no1 +COc1ccc2oc(CNc3ccc(S(C)(=O)=O)nc3)cc2c1 +Cc1csc(CNc2cc(S(C)(=O)=O)ccc2F)n1 +Cc1ccc(-c2noc(CN(C)S(=O)(=O)c3ccccc3)n2)cc1 +CCNC(=O)c1ccc(NC(=O)c2cc(Cl)c[nH]2)c(C)c1 +O=C(Cc1ccncc1)Cc1ccc(Br)cc1F +CCOCCc1nc(C2CCOC2)nn1C1CCCCC1 +Cn1cc(-c2ccncc2)cc1C(=O)NCCC1=CCCCC1 +CCOc1ccc(-c2cc(C)[nH]c(=O)c2C#N)cc1OCC +Cc1ccc(CNS(=O)(=O)N2CC(C)OC(C)C2)s1 +COc1ccccc1Cc1nnc(SC2CCOC2=O)o1 +CN(C)C(=O)N1CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +Cc1cccc(C)c1NC(=O)N1CCc2cc(F)ccc2C1 +O=C(NC(CN1CCOCC1)c1ccccc1)c1ccccc1 +CCN1CCN(C(=O)c2onc(C(=O)OC)c2N)CC1 +CC(=O)Nc1ccc(SCC(=O)N2CCCC2)cc1 +NC(=O)c1nnn(Cc2ccc(Cl)cc2)c1N +Cc1cccc2cc(C(=O)N3CCC4(CC3)CN(C)C(=O)O4)n(C)c12 +COc1ncccc1CNC(=O)NC(C)c1cccs1 +CCC(C)NC(=O)c1ccccc1SCC(=O)NC(C)C +C=CCNC(=O)c1cccc(OCc2nnnn2C(C)C)c1 +Cc1ccccc1C(=O)Nc1cc(S(C)(=O)=O)ccc1Cl +CCN(C)S(=O)(=O)NCC1(c2ccc(F)cc2F)CC1 +CCCn1c(C)cc(C(=O)COC(=O)c2cnccn2)c1C +Fc1ccc(C(CNCc2ccccc2F)N2CCOCC2)cc1 +Cc1noc(COC(=O)c2ccc3c(c2)OCO3)n1 +COC(=O)Nc1cccc(C(=O)NC(C)(C)c2cccc(F)c2)c1 +Cn1ccc(-c2cc(-c3ccc(O)cc3Cl)c(C#N)c(N)n2)c1 +O=C1COc2ccc(C(=O)Cn3cnc4ccccc4c3=O)cc2N1 +CCc1nnc(C(C)Sc2nnc3cc(C)c4ccccc4n23)o1 +Cc1ccc(C(=O)CSc2nncs2)cc1C +COC(=O)c1cc(-c2cnn(C)c2)nc2onc(C)c12 +COc1cccc(C(CNS(=O)(=O)c2ccc(F)cc2)OC)c1 +CCOc1cc(C)ccc1NC(=O)c1ccsc1 +Cn1nc(CCC(=O)Nc2ccccn2)ccc1=O +Nc1c(S(=O)(=O)c2ccc(F)cc2)nnc2ncnn12 +CSc1ncc(-c2nnc(SCc3ccccc3)n2C)n1C +CCOC(=O)c1cc(=O)[nH]c2c1c(C1CC1)nn2-c1ccc(F)cc1 +COc1nn(C)cc1C(=O)N1CCC(Oc2ncccn2)CC1 +CC(=O)c1c(C)[nH]c(C(=O)CSc2nnc(C(C)(C)C)o2)c1C +CC(NC(=O)c1ccco1)c1nc(-c2ccncc2)no1 +N#CCCCn1nnc(-c2ccc(Br)cc2)n1 +COc1cccc(CC(=O)N2CC(c3nc(-c4ccccc4)no3)C2)c1 +OC(Cn1nnc2cc(Cl)c(Cl)cc21)c1ccccc1 +CC(Oc1ccc2ccc(=O)oc2c1)C(=O)NCc1cccnc1 +CC(=O)c1cccc(S(=O)(=O)Nc2cc(C)nn2C)c1 +O=C(Cn1cnnn1)N1CCOc2cccc(F)c21 +O=C(NC1(c2ccc(Cl)c(Cl)c2)CC1)c1cnccn1 +COCC(=O)N(Cc1ccco1)CC(F)(F)F +Cc1nc(NC2CCCCC2)sc1C(=O)NCc1ccccn1 +CNC(=O)c1ccccc1C#CCNC(=O)CCc1c(C)noc1C +Cc1noc(C)c1C(=O)N1CCc2sccc2C1 +CCCCNC(=O)c1snc(-c2ccccn2)c1NC(=O)C(C)C +COC(=O)C(C)CNC(=O)Nc1cc(OC)ccc1F +OCC#Cc1ccc(-c2nccn2CCN2CCOCC2)s1 +Cc1ccc(Cl)cc1OC(=O)CCCCNC(N)=O +Cc1ccc(NC(=O)Cn2ccc(=O)c3ccccc32)cc1Cl +COC(=O)CCCC(=O)c1ccc2c(c1)N(C)CC(C(C)C)O2 +CC(=O)Nc1ccc(OC(=O)c2cc3ccccc3c(=O)[nH]2)cc1 +CN(C)C(=O)c1csc(NC(=O)c2cc(F)cc(F)c2)n1 +CCCC(=O)Nc1cccc(NC(=O)C2COc3ccccc3O2)c1 +Cc1cccc2c(=O)n(CC(=O)Nc3ccc(Cl)cc3F)cnc12 +COc1cc(C(C#N)C(=O)C2CC2)cc(OC)c1OC +Cc1cc2nnc(SCc3cccc(C#N)c3)n2c(C)n1 +O=C(c1cnn(-c2ccccc2)c1C1CC1)N1CCCCCC1 +Cc1cc(C)c2nc(NC(=O)Cc3c(C)nc(C)[nH]c3=O)sc2c1 +Cc1noc(-c2ccc(NC(=O)Cc3ccccc3)cc2)n1 +CCCC(=O)c1ccc(S(=O)(=O)NC(C)CC)cc1 +CC(C)CNC(=O)C1CC(=O)N(c2ccc(F)cc2)C1 +Cc1nc2ccccc2nc1Cn1c(=O)oc2ccccc21 +O=C(Cc1ccccc1F)NCC(O)c1cccc(C(F)(F)F)c1 +CCOc1cc(C)nc(N2CCN(C(=O)Cn3cc(C)cn3)CC2)n1 +CCC(NC(=O)N1CCCC(NC(C)=O)C1)c1cc(F)ccc1F +CCOC(=O)C1CCCN(C(=O)c2ccc(Br)cc2)C1 +COCCOC(=O)C1CCN(CC(F)(F)F)CC1 +CN(C(=O)c1cccc(F)c1)C1CCc2ccccc21 +CCn1cc(NC(=O)c2nn(CC)c3ccccc3c2=O)cn1 +CN(C(=O)n1cnc2ccccc21)c1ccccc1 +O=C1CN(C(=O)COC(=O)c2ccc(-n3cccc3)cc2)CCN1 +Cc1cccc(OCCCC(=O)NCC(F)(F)F)c1 +CC(C)(C)OC(=O)Nc1ccc(NC(=O)c2ccoc2)cc1 +Cc1ccc(CNC(=O)NCC(C)(O)c2ccsc2)s1 +COc1cccc(COC(C)C(=O)NCc2ccc(Cl)cc2)c1 +Cc1cc(C)c(CNC(=O)c2occc2-c2ccccc2)c(=O)[nH]1 +O=C(Nc1cnccn1)C1Cc2ccccc2CN1 +COCC(=O)N(Cc1ccc2[nH]ccc2c1)C1CC1 +CC(=O)Nc1cccc(CNC(=O)Nc2ccncc2)c1 +NS(=O)(=O)CCNC(=O)c1ccccc1C(=O)c1ccccc1 +CC(C1CC1)N(C(=O)c1ccc(-n2cnc3ccccc32)nc1)C1CC1 +CCOc1cc(CNC(=O)N2CCC(CO)CC2)ccn1 +CC(Oc1cccc2ccccc12)C(=O)NCc1ccco1 +NS(=O)(=O)c1ccc(Cl)c(C(=O)Nc2nccs2)c1 +COC(=O)CNC(=O)c1ccccc1CCc1ccccc1 +CCCc1c(CO)nnn1-c1cccc(C(F)(F)F)c1 +COc1ccccc1-n1ccnc(NCc2ccccc2Cl)c1=O +Cc1occc1COC(=O)Cn1c(=O)cnc2ccccc21 +CCOc1ccc2c(c1)C(c1ccc(OC)c(O)c1)NCC2 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+Cc1nc(C)c(CCC(=O)Nc2cc(F)cc(F)c2)c(=O)[nH]1 +CN(CCNC(=O)c1ccc(-n2cccc2)cc1)C(=O)OC(C)(C)C +C=CC1CCN(C(=O)Nc2cc(C)cc3cccnc23)CC1 +COc1cccc(C(=O)c2c(N)oc3ccccc23)c1 +O=C1CNc2ncnc(NCCn3cc(Cl)cn3)c2N1 +O=C(NCC1Cn2nnc(-c3cccc(F)c3)c2CO1)C1CCOC1 +Cc1ccc(C)c(CC(=O)NC(C)C(=O)N2CCOCC2)c1 +CC(O)CNC(=O)Cc1ccc(OC(F)F)cc1 +CC(C)c1ncc(Cl)c(C(=O)NC(C)c2ccco2)n1 +NC(=O)c1n[nH]c2ccc(NC(=O)CNC(=O)c3ccccc3)cc12 +Cc1cc(C)n(-c2ccccc2NC(=O)Cc2ccccc2F)n1 +Cc1cc(C2CCCN(C(=O)c3ccsc3)C2)n[nH]1 +Cc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cc1OC(F)F +CCC1CN(S(=O)(=O)c2ccc(F)c(NC(C)=O)c2)CC(C)O1 +Cc1ncsc1CCOC(=O)c1ccc(-n2cncn2)cc1 +O=C1CCCc2nc3c(cc21)C(O)Oc1ccccc1-3 +COc1cccc(CNC(=O)NC(C)C)c1OC +N#CCOc1ccc(NC(=O)Cc2cccc(F)c2)cc1 +Cc1ccc(C)c(CC(=O)N2CCNC(=O)C2(C)C)c1 +O=C(Oc1ccccc1N1CCOCC1)c1ccco1 +CCN(Cc1ccccc1)C(=O)c1nn(C)c2ccccc2c1=O +COc1cccc(NC(=O)COC(=O)c2ccccn2)c1 +CC(=O)Nc1cccc(OC(=O)Cc2c(F)cccc2F)c1 +Cc1ccc(NCc2ccc(C(N)=O)cc2F)c(C)c1 +Cc1cccc(C2(Cc3cccc(Cl)c3)NC(N)=NC2=O)c1 +Clc1ccccc1CNC1=NC=NC2=NC=NC21 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+CC(NS(=O)(=O)c1ccc(F)cc1)C(=O)NC1CCCC1 +COc1cn(-c2ccccc2)nc1C(=O)N1CCCN(C(C)=O)CC1 +COc1ccc(CCCC(=O)N2CCc3ccccc32)cc1 +Cc1ccccc1N1CCN(CC(=O)N2CCCCC2C)CC1 +CC1CCCC(C)C1NC(=O)C1CCN(c2cnccn2)CC1 +COc1ccccc1N1CCN(C(=O)c2sc(C)cc2OC)CC1 +N#CC(C(=O)C1(c2ccccc2)CC1)c1ccccn1 +CCOC(=O)C(C)NS(=O)(=O)c1ccc(C)c(F)c1 +CCCCNC(=O)c1nnc(C(=O)Nc2cccc(Cl)c2)s1 +O=C1CCC(C2NCCc3cc4c(cc32)OCC4)N1 +CC(Sc1ccccc1Cl)C(=O)N1CCCC(CO)C1 +CC(Nc1ccc2c(c1)CCC(=O)N2)C(=O)NCc1ccccc1 +Cn1c(CNC(=O)c2cccc(-n3cnnn3)c2)nnc1C1CCC1 +CC(Oc1cccc(Cl)c1)C(=O)NC(C)(C)C#N +Cc1cc(C(=O)Nc2ccc(C(N)=O)cc2)nn1-c1ccccc1 +COc1ccc(F)cc1C(C)NC(=O)Nc1cc(C)on1 +O=C(N1CCCC(O)C1)C1(c2cccc(Br)c2)CC1 +CC(C(=O)NC1CC1)N1CCN(S(=O)(=O)C(C)C)CC1 +Fc1cccc(F)c1CNc1cnn(-c2ccccc2)c1 +COC(=O)CCCCNC(=O)Nc1ccccc1C +Cc1cccc(C)c1NC(=O)Cc1nc2scc(C)c2c(=O)[nH]1 +Cn1cnc2cc(C(=O)OCCOc3cccnc3)ccc21 +CC(C)S(=O)(=O)NC(c1ccccc1)c1ccccn1 +COc1ccc(CCC(=O)N(C)C(C)C)cc1OC +CCc1ccc(C(=O)N(CCO)C2CCCCC2)o1 +Cc1nc(-c2ccc(C(=O)N(C)c3ccccc3)cc2)no1 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+CC(NC(=O)Cc1cccc(OCC#N)c1)C1CN(C)CCO1 +CC(=O)c1ccc(F)c(C(=O)Nc2ccccc2)c1 +CC(=O)c1cccc(NC(=O)C(C)Sc2ncn[nH]2)c1 +CCCCn1nnc(NC(=O)COc2ccccc2C)n1 +Cc1cnn(CCC(=O)N(CC(=O)Nc2ccc(F)cc2)C(C)C)c1 +CCOC(=O)CCN1CCN(C(C)C(=O)N2CCCC2)CC1 +CN(CCC(F)(F)F)C(=O)Nc1cccc(C#N)c1 +Cc1cc(-c2nn3c(-c4cc5ccccc5o4)nnc3s2)no1 +CCOCCn1ccc2ccn(CC3CC3)c2c1=O +CNC(=O)c1ccc(Nc2ncnc(SC)c2C#N)cc1 +C=CCc1cccc2cc(C(=O)NCCN3CCOCC3)c(=O)oc12 +CC(=O)N1CCCc2cc(NCc3ccc(C)s3)ccc21 +CSc1ccccc1C(=O)NCCCn1cccc1 +Cc1cc(C(=O)NC2CCC2c2ccccc2)c2c(C)noc2n1 +CCN(C(=O)COc1ccc(C(C)=O)cc1OC)C1CCCCC1 +NC(=O)COC(=O)c1ccc(SCc2ccccc2)cc1 +O=C(CCNC(=O)c1ccc2ccccc2c1)Nc1nc[nH]n1 +C=CCNC(=O)c1nnn(-c2ccc(C)c(Cl)c2)c1C +CCOC(=O)CNc1ncc(Br)c2ccccc12 +COc1ccc(OCc2cc(=O)n3cc(C)ccc3n2)c(C(N)=O)c1 +Cc1cccc2oc(=O)n(C3CCN(C(=O)CC(C)C)CC3)c12 +C#CCN1CCN(C(=O)NCc2ccc(OCCOC)cc2)CC1 +COc1cccc(CC2(CO)CCCN(c3ncccn3)C2)c1 +O=C1CC2CCC(CN1)N2C(=O)c1ccc2ncsc2c1 +CCOC(=O)CNCc1ccc(F)c(Cl)c1F +COc1ccccc1N1CC(C(=O)N(C)CCC(F)(F)F)CC1=O +COC(=O)C(C)Sc1ccccc1C(=O)N(C)Cc1cc(C)on1 +O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1nc2ncccn2n1 +Cc1nc2ccccc2c(=O)n1CC(=O)N(C)C1CCCCC1 +Cc1nc2c(c(C)nn2C)c(C)c1CCC(=O)NCc1cccs1 +Cc1ccc(NC(=O)Cn2c(N)nc(C#N)c2C#N)c(Cl)c1 +N#Cc1csc(C(=O)OCCCOC2CCCC2)c1 +O=C(NCc1cscn1)NCc1nncn1-c1ccccc1 +C#CCCNC(=O)c1ccc(Br)cc1 +COc1ccccc1CC(=O)NC1CCCCC1C +CCOCc1nc(N)[nH]c(=O)c1Cc1ccc(OC)cc1 +COC(=O)c1sc(NC(=O)c2n[nH]c3ccccc23)nc1C +C=CCN(CC=C)C(=O)C(C)NC(=O)C1CCCN(C(C)=O)C1 +COC(=O)C(CC(C)C)NC(=O)NCc1ccc(C)cc1 +CCOC(=O)c1cn2nc(C(F)(F)F)nc2nc1C +NC(=O)c1ccc(-c2nnn(Cc3ccc(F)c4cccnc34)n2)cc1 +O=C(COC1CCCCC1)NC1CCCN(c2ccccc2)C1=O +Cc1onc(-c2ccccc2)c1-c1nnc(Cn2cnc(C#N)n2)o1 +O=C(Cc1c(Cl)cccc1Cl)NC1CCC(O)CC1 +CC(=O)NC1CCN(S(=O)(=O)N2CCC(C(C)(C)C)CC2)CC1 +COc1ccccc1CC(C)NCc1ccnc(C)n1 +O=C(COc1ccccc1Cl)Nc1ccon1 +COc1ccc(CNc2ccc(Br)cn2)cc1 +CCc1ccccc1-n1nnc(CO)c1C(F)(F)F +CC(C)Cn1cnnc1C1CCCN1C(=O)Cc1ccc(Cl)cc1 +Cc1ccc(S(=O)(=O)NCc2ccc(OC(C)C)cc2)s1 +CCOc1ncccc1C(=O)N1CCn2cccc2C1CC +CC(NC(=O)Nc1ccncc1)c1ccc(S(N)(=O)=O)cc1 +O=C(Nc1ccc2c(c1)OCO2)Nc1cnn(-c2ccccc2F)c1 +COCCCC1CCCN(C(=O)Cc2c(C)nc(N)nc2C)C1 +OC(CNCc1ccc(F)c(F)c1)c1ccccc1Cl +CCc1ccc(NC(=O)NCCNC(=O)C2CC2)cc1 +Cc1ccc(NC(=O)NCc2ccccc2F)cc1-n1cnnn1 +Cc1nc(C)c(CNC(=O)c2ccc(CCC(C)(C)O)cc2)s1 +COCC1CN(C(=O)CC2C=CCC2)Cc2nnn(CC3CC3)c21 +CC(NC(=O)Nc1ccc2c(c1)COC2)C1CCOC1 +Cc1ccc(C)c(Cn2nc3n(c(=O)c2=O)CCN3c2ccccc2)c1 +COCCN1CCN(Cc2ccc(Cl)c(Cl)c2)CC1=O +Cc1ccccc1S(=O)(=O)N1CCOC(C)(C(N)=O)C1 +COc1ccc(C(O)CCCC(=O)NC(C)C)cc1Cl +O=C(NCc1ccccc1)c1ccccc1OC(=O)C1CC1 +O=C(Nc1cccnc1N1CCCCC1)c1cnc2ccccn2c1=O +O=C(CCn1ccc2ccccc21)Nc1ccccc1N1CCCC1=O +COCCN(Cc1ccco1)C(=O)Nc1ccc(F)c(Cl)c1 +O=C1Nc2ccccc2NC12CCN(c1ncccc1Cl)CC2 +CNC(=O)C1CCC(NC(=O)COC(C)C)CC1 +CC(=O)N(C)Cc1cccc(NCc2cnn(-c3ccccc3)n2)c1 +CC(C)CCC(C)NS(=O)(=O)c1cc(N)ccc1F +CCCn1nnnc1CSc1nc2c(cc1C#N)CCCC2 +COC(=O)c1coc(S(=O)(=O)Nc2c(C)n[nH]c2C)c1 +Cc1cccc(OCCc2noc(N)c2-c2ccccn2)c1 +O=C(NCc1ccc(F)cc1)Nc1cccc(N2CCNC2=O)c1 +CC(=O)N1CCc2cc(C(=O)C(C#N)c3nc(C)cs3)ccc21 +COc1cc(C(=O)Nc2cc(F)cc(F)c2)ccc1OC(F)F +c1coc(-c2nc(CSc3nnc(Cn4cncn4)o3)cs2)c1 +Cc1cc(NC(=O)CCCc2ccccn2)ccc1C(=O)N(C)C +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(OC(F)(F)F)cc2)c1C +CC(C)NC(=O)C(Cc1ccccc1)NC(=O)c1cccs1 +Cc1nnc2n(CCOc3ccc(F)cc3)c3ccccc3n2c1=O +COC(=O)c1ccc(NC(=O)c2ccc(NC(C)=O)cc2)cc1 +CC1CCCCN1c1nc(C2CC2)c(CC#N)s1 +O=C(NCCCNC(=O)c1cc2n(n1)CCCO2)c1ccsc1 +COc1ccc(OC)c(S(=O)(=O)Nc2ccnn2C(C)C)c1 +O=C(Cn1nnc(COc2ccccc2)n1)NCC1CCOC1 +CC(=O)NCCNC(=O)NCCCc1cccc(F)c1 +COc1cc(C)c(CN2CCOCC2C2CC2)cc1OC +COCC(NC(=O)c1ccc(C)cc1O)C(N)=O +CC(C)C(=O)N1CCC(C(=O)Nc2cccc(-c3ccn[nH]3)c2)CC1 +CCN(CC(C)C#N)S(=O)(=O)c1ccc(C)c(C)c1 +NC(=O)C1CCN(C(=O)CCC(=O)c2ccc(F)c(F)c2)CC1 +O=C(Nc1cccc(N2CCCCCC2)c1)c1cscn1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)N(C)Cc1ccccc1F +CCn1nc(-c2ccc(OC)c(C(C)C)c2)cc(N)c1=O +CC(=O)N1CCCC1C(=O)NC1CCN(c2ccccc2)CC1 +Cn1c2c(c(=O)c3ccc(Cl)c(F)c31)CNCC2 +Cc1c(C(=O)NC(C)C(=O)NC(C)(C)C)cnn1C +Cc1ccc(OC(=O)c2ccc(C(N)=O)nc2)c(Br)c1 +Cc1c(C(=O)Nc2ccccc2O)cnn1-c1ccccc1 +CCc1cc(C(=O)Nc2ccc(Oc3cccnc3)c(C)c2)[nH]n1 +O=C1COCc2[nH]c3cccc(Br)c3c21 +COc1cc(C(=O)N2CCOc3ccccc32)cc2c1OCCO2 +[H]N=c1n(C)c2ccccc2n1CCOc1ccccc1OC +CCN(Cc1ccoc1)C(=O)Nc1cc(C)cc2cccnc12 +CCCN(CC(=O)Nc1ccccc1C)C(=O)c1cc(C(C)=O)c[nH]1 +CCOC(=O)N1CCC(NC(=O)c2ccc3ccccc3c2)CC1 +Nc1c(-c2cccnc2)nsc1C(=O)Nc1ccncc1 +CSc1ccc(CC(=O)N2CCC3(CCCN(C)C3=O)C2)cc1 +Cc1ccc(C(=O)N2CCCC2C(=O)c2cccs2)cc1 +Clc1ccc2[nH]c(C3Cc4ccccc4CN3)nc2c1 +CCc1noc(CC)c1CNC(=O)NC(C)C(=O)Nc1ccccc1 +COc1ccc(CN(C)C(=O)c2ccc(Cl)cc2)c(OC)c1 +Cc1nc(CN2CCN(Cc3cnc(C(C)(C)C)s3)CC2)oc1C +COc1cccc(C(=O)Nc2cccc(S(C)=O)c2)c1F +COc1ccc(C(NC(=O)c2ccc(C)[nH]c2=O)C(C)C)cc1 +CC(C)N1C(=O)C(=O)c2cc(Br)cc(Br)c21 +CC(Nc1ncnc2ccsc12)C(=O)NCC(F)(F)F +Cc1ccccc1C(=O)N(C)C(C#N)c1ccc(F)cc1 +N#Cc1cnc2ccccc2c1NCC1CCCOC1 +CC(C(O)c1ccccc1)N(C)C(C#N)c1ccc(N)cc1 +CS(=O)(=O)Nc1ccn(Cc2ccc(Cl)cc2Cl)n1 +CN(CC1CCN(c2ccccc2)C1)C(=O)c1ccccc1C#N +CN(Cc1cnn(C)c1)C(=O)c1ccccc1NC(=O)c1ccccc1 +CC(C)c1ccc(C(=O)NCCNC(=O)c2ccncc2)cc1 +CC(C)CC(=O)NCC(=O)c1ccc(Br)cc1 +CNC(=O)NCC(=O)NC(C)c1cc(C)oc1C +CC(=O)Oc1ccc(C(=O)Nc2nc3c(s2)CCC3)cc1 +COCCNc1nc(-c2sc(C)nc2COC)cs1 +CC(C)N(Cc1ccccc1)S(=O)(=O)c1cccs1 +Fc1ccccc1-c1ncncc1Br +Cn1cccc(NC(=O)C2CCCN(C(=O)C3CC3)C2)c1=O +COc1cccc(OC)c1C(=O)Nc1ccc(CCO)cc1 +Nc1c(NC2CCCCC2)ncnc1N1CCCCC1 +CCCn1c(SCC(=O)c2cc(C)n(C)c2C)n[nH]c1=O +NC(=O)CNC(=O)C1CCCN1C(=O)OCc1ccccc1 +Cc1ccc(CC(=O)NCCS(=O)(=O)c2ccccc2)cn1 +COc1cc2nc(-c3cc(Cl)ccc3OC)oc(=O)c2cc1OC +COc1ccccc1CN(C(=O)C1CC2CCC1O2)C1CC1 +O=C(NCCC(O)c1cccc2ccccc12)c1ccno1 +CC(c1ccccc1F)N(C)S(=O)(=O)N1CCCCC1 +O=C(NCc1ccco1)C1CCN(c2ccccc2-n2cccc2)C1=O +N#Cc1cnn2c1NC(c1ccc(Cl)cc1)CC2C(F)F +Cc1ccc(C(N)=O)cc1NC(=O)Cc1cccc(OCC#N)c1 +Cc1cc(C(=O)Nc2nc(-c3ccc(C#N)cc3)cs2)nn1C +Cc1ccc(C)c(C(=O)N2CCN(C(=O)c3ccc(O)cc3)CC2)c1 +CCOCCC1(C(=O)N2CCc3cc(F)ccc3C2)CCC1 +O=S(=O)(NCCc1ccc(O)cc1)c1ccccc1F +O=C(C1CCC1)N1CCC(c2noc(-c3ccccc3)n2)CC1 +CC(C)C(=O)NCCN1CCN(c2ccc(F)cc2)CC1 +CN(C1(C#N)CCC1)S(=O)(=O)c1c(F)cc(F)cc1F +Cn1cnnc1CNCc1cc(=O)n(C)c(=O)n1C +CNC(=O)c1cccc(CNC(=O)NCC2CCCC(C)C2)c1 +COC(=O)c1cccc(C)c1NCCc1ccccc1 +CCOc1ccc(NC(=O)NCc2nnc3n2CCCCC3)cc1F +Cn1cc(CNC(=O)CCOc2ccccc2-c2ccccc2)cn1 +COCC(=O)N1CCc2ncnc(C3CCOC3)c2CC1 +COc1cc2[nH]c(=O)n(CCN3CCOCC3)c(=O)c2cc1OC +CC1CC(C)CN(S(=O)(=O)c2cccc3cccnc23)C1 +COc1cccc(CCC(=O)NC(C)c2c(C)noc2C)c1 +O=C(CC1Sc2ccccc2NC1=O)OCCCc1ccccc1 +Cn1cc(C(=O)NCCn2c(=O)[nH]c3ccccc32)c(C(C)(C)C)n1 +Cc1ccc(C(=O)N(C)C(C)c2ccccc2Cl)c(C)n1 +CC(C)c1cc(C(=O)NC(c2ccccc2)c2ccccn2)no1 +CC(C)CCNC(=O)NCCc1cn2ccccc2n1 +CN(C(=O)CCN1C(=O)C(C)(C)Nc2ccccc21)c1ccccc1 +CCC(C)n1c(C)cn2c3c(=O)n(CC)c(=O)n(C)c3nc12 +O=S(=O)(c1ccccc1)N(CCCO)C1CCCCC1 +CC(Oc1ccccc1Cl)C(=O)N1CCOCC1 +CC(=O)c1ccc(S(=O)(=O)NC2CCc3ccccc32)cc1 +CCNC(=O)N1CCN(C(=O)c2ccccc2Br)CC1 +CCNC(=O)Cc1csc(-c2ccc3c(c2)OCO3)n1 +Cc1cc(C)n(CCN2CCN(C(=O)c3ccc(C)c(C)c3)CC2)n1 +Brc1ccc2nnc(-c3ccncn3)n2c1 +CC(=O)Nc1cccc(Nc2ccc(F)c(F)c2)c1 +COCCN(Cc1ccc(C#N)cc1)Cc1cccn1C +O=S(=O)(Nc1ccccc1)c1ccc(-c2ccno2)s1 +COc1ccc(-c2n[nH]c(=O)c(Cc3ccc4c(c3)OCO4)n2)cc1 +O=C1CCc2ccccc2N1Cc1nc(-c2cccc(Cl)c2)no1 +Cc1ccsc1C(=O)Nc1ccn(-c2ncccc2Cl)n1 +COC(=O)CN(C)C(=O)c1cc(F)ccc1Br +Cc1cc(C)c(CNC(=O)N(C)CC(C)(C)O)c(C)c1 +O=C(NC1CC(=O)N(Cc2ccccc2)C1)c1ccc(F)cc1F +CCOc1ccc(NS(=O)(=O)C(C)C)cc1CO +Cc1ccc(C)c(OCCC(=O)N2CCC(O)CC2)c1 +Cc1cc(C)c2nccc(NC(=O)c3ccccn3)c2c1 +CCc1nc(CC(=O)Nc2ccccc2SCC(C)C#N)cs1 +O=C1C2CN(c3cnccn3)CC2CN1CC1CC1 +CCC(CC)C(=O)Nc1ccc2c(c1)CC(=O)N2C +Cc1ccc(C(=O)Oc2ccc3c(c2)OCO3)cn1 +CNC(=O)C(C)NC(=O)CNC(=O)CC(C)(C)C +CCN(CC)C(=O)C(C)Nc1ccc(NC(=O)C2CC2)cc1 +CNC(=O)Cn1nc(C#N)cc1-c1ccc2c(c1)ncn2C +Cc1ccn(Cc2ccc(N)cc2Br)c(=O)c1 +Cc1nc(C)n(-c2ccccc2NC(=O)NCC2(C3CC3)CCC2)n1 +CC(C)CCN1CC2(COC(C(=O)N3CCCC3)C2)c2ccccc21 +CCCOC(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 +CN(C)C(=O)c1ccc(CN2CCc3c(Cl)cccc32)[nH]1 +Cc1ccccc1C=Cc1nn2c(-c3ccncc3)nnc2s1 +Cc1ccc(N2CCC(NC(=O)N3CCOCC3C3CC3)C2=O)cc1 +CCCc1ncc(C(=O)NCC2CCCO2)c(N)n1 +CCn1nc(C)c(C(C)n2cc(-c3ccc(OC)nc3)nn2)c1C +CC(CCCO)NC(=O)Nc1cc(Cl)ccc1N1CCOCC1 +CCOC(=O)C(NCC1CCCO1)c1cnn(C)c1 +CCc1ccccc1NC(=O)NC1CC(=O)N(c2cccc(F)c2)C1 +O=C(CCC(F)(F)F)NCc1cccc(Oc2ccccn2)c1 +CCc1cc(N)cc2c(CC(=O)NCc3ccccn3)noc12 +O=C(NCc1ccco1)c1cccc2c1C(=O)N(Cc1cccnc1)C2 +CC(NC(=O)Cc1noc2ccc(N)cc12)c1ccccc1 +COc1ccc(-c2ccc(=O)n(Cc3ccccc3)n2)cc1 +COc1cc(C#N)ccc1OCC(=O)Nc1cc(C)nn1C(C)(C)C +Cn1c(CN2CCOCC2)nnc1SCc1cccc(F)c1 +O=C(NCC1CCOC1)C(Cc1ccccc1)n1cnnn1 +CCc1nc(CC(=O)N(CC)Cc2c(F)cccc2F)cs1 +CS(=O)(=O)N1CCC(NC(=O)c2ccc(C#N)cc2)CC1 +COc1ccccc1C(=O)CNC(=O)Cc1cccs1 +COC(=O)C(NS(=O)(=O)c1cccc(Cl)c1F)C(C)C +CCN(CC(=O)Nc1ccc2c(c1)OCCO2)C(=O)Cn1cnnn1 +CNS(=O)(=O)c1cc(C(=O)NCc2ccccc2C)ccc1OC +CC(C)c1ccc(CC2Oc3cc(N)ccc3NC2=O)cc1 +O=C(NCCn1nc(-n2cncn2)ccc1=O)c1ccsc1 +COc1ccc(F)cc1C(=O)COc1ccc(Cl)cc1C(N)=O +O=c1[nH]ncc(NCCOCc2ccc(Cl)cc2Cl)c1Cl +CC(Sc1ncnc2c1cnn2C)C(=O)N1CCc2ccccc21 +COc1ncccc1CNC(=O)Nc1ccccc1Cl +C=CCNC(=O)COc1nc(-c2cccs2)cc(C(F)(F)F)n1 +COC(=O)c1c(C)nn2c1ncc1c(=O)n(C(C)C)ccc12 +Cc1cccc(CC2COCCN(Cc3cnc[nH]3)C2)n1 +O=C(CCCc1cccs1)NC1CCN(c2ccccc2F)C1=O +CCN1CCN(C(=O)CCOc2ccccc2F)CC1 +CC(Sc1ccc(N)cc1)C(=O)Nc1cccc(Cl)c1 +CC(NC(N)=O)C(=O)N(C)CCOc1ccc(F)cc1 +Cc1cc2c(c(N)nn2C)c(=O)n1Cc1ccccc1 +O=C(NCc1cn2ccsc2n1)c1ccnc(OC2CCC2)c1 +CCCn1c(-c2cccs2)ccc(C(C)(C)O)c1=O +Cc1cccc(C(=O)Nc2c(C)nc3c(C)cccn3c2=O)c1 +CC(=O)c1ccccc1C(=O)NCCCCN1CCOCC1 +Cc1ccc(C(=O)NCC(C)N(C)c2ccccc2)cn1 +CS(=O)(=O)Nc1ccc2c(c1)CN(C(=O)c1cccs1)CC2 +Cc1cc2nc(C3CC3)n(CC(=O)Nc3cccc(C#N)c3)c2cc1C +CCC(CO)NC(=O)NCCc1cccc(C(=O)NC)c1 +Cc1cc(C(=O)Nc2ccc(OCC(N)=O)cc2)c(C)n1C(C)C +CC(C)(CNC(=O)Cc1ccccc1F)c1ccncc1 +CN(C(=O)c1cccc2ccccc12)c1ccccc1S(C)(=O)=O +CCOCc1nc(C2(C(N)=O)CC2)n(-c2ccc(OC)cc2)n1 +N#Cc1cccnc1NCCOC(=O)C1CC=CCC1 +COc1cc(C)ccc1S(=O)(=O)NCc1cccnc1 +COc1ccccc1CNC(=O)CSc1nnc2n1CCCCC2 +CNC(=O)C(C)NC(=O)c1c(Cl)ccc(Cl)c1Cl +CCS(=O)(=O)N1CCC(C(=O)Oc2ccc(Cl)cc2)CC1 +COC(=O)c1cccc(NC(=O)N2CCCCC2C)c1 +CC(C)N1CC(C(=O)N2c3ccccc3CC2C)CC1=O +CCOc1cc(CNC2CCCCNC2=O)cc(Cl)c1OC +N#CC1(C(=O)NCc2ccc3c(c2)OCO3)CCCC1 +Cc1ccc(NC(=O)CNC(=O)c2ccccc2Cl)cc1 +COc1ccc2c(c1)CN(C(=O)C(OC)c1ccccc1)CC2 +CCOC(=O)C(C)NC(=O)Cc1cc(Cl)ccc1OC +Cc1ccc(CN(C)C(=O)Nc2ccc3c(c2)CCC(=O)N3)s1 +Cc1cc(S(=O)(=O)NCC2CN3CCCCC3CO2)ccc1F +Cc1c(NS(C)(=O)=O)cccc1C(=O)Nc1ccc(Cl)cc1 +CC(C(=O)Nc1cccc(F)c1)n1c(=O)[nH]c2ccccc2c1=O +Cc1nc(-n2cccc2)sc1C(=O)NCc1c(C)nn(C)c1C +CCOc1cccc(COC(=O)c2nc(C)sc2C)n1 +CCOC(=O)c1nc(CC(=O)NCc2ccccc2)no1 +N#Cc1cccc(CNC(=O)NCc2cccc(Cn3cccn3)c2)c1 +CN(C)C(C(=O)N1CCC2(CCO2)CC1)c1ccccc1F +CC(=O)c1ccc(NC(=O)CCn2ncc3ccccc32)cc1 +CCC(=O)N1CCC2(CC1)CC(c1ccccc1)C(=O)N(CC)C2 +COc1cccc(C(=O)Nc2cc(NC(=O)C3CC3)ccc2C)c1F +CCOc1ccccc1C(=O)NC(CO)C(O)c1ccc(N)cc1 +Cn1ncc2c(=O)[nH]c(N3CCN(C(=O)CC4CCCC4)CC3)nc21 +COC(=O)Nc1cccc(C(=O)N(C)Cc2cccc(O)c2)c1 +CCCOc1ncccc1CNC(=O)Cc1cccc(Cl)c1 +N#CCn1nnn(-c2ccc(Cl)cc2Cl)c1=O +COCCN(Cc1cnn(C)c1)C(=O)c1cn(-c2ccccc2)nn1 +Cc1cc(NC(=O)COc2cccc(N3CCCC3=O)c2)n(C)n1 +CN1CC(C(=O)N2CCC(C(N)=O)c3ccccc32)CC1=O +O=c1c2ccccc2c(-c2ccc(F)cc2)nn1CCO +COc1ccccc1CCNc1ncnc2[nH]cnc12 +COC(=O)c1sccc1NC(=O)COc1cccc(C(C)=O)c1 +CN(Cc1ccncc1)C(=O)c1cccnc1Nc1ccccc1F +O=C(CCCc1cccs1)N1CCOc2ccc(F)cc21 +O=C(NCc1cc(=O)[nH]c2ccccc12)NC1CC1C1CCCCC1 +CCCCNC(=O)c1cccc(S(=O)(=O)NCC)c1 +O=C(Nc1cccc2cn[nH]c12)c1occc1-c1ccccc1 +CC(C)NC(=O)CCC(O)c1ccc(Cl)c(N)c1 +CCOc1ccccc1CNC(=O)CCc1c(C)n[nH]c1C +O=C(Nc1cncnc1-n1cccn1)c1cc(F)c(F)cc1F +CCOC(=O)NCC1CCN(S(=O)(=O)c2cccnc2)CC1 +CCOC(=O)CCNC(=O)Nc1ccc(Cl)c(C#N)c1 +CC(=O)NC(C(=O)N1CCN(C(=O)c2cccs2)CC1)C(C)C +CCC(C)NC(=O)c1ccc(NC(=O)c2cccn2C)cc1 +CCCC(=O)N1CCCC(C(=O)Nc2cc(F)ccc2Cl)C1 +COc1ccc(CC(=O)NCC2Cc3cc(F)ccc3O2)cc1 +Cc1ccc(CNC(=O)c2ccc(CSc3ncn[nH]3)cc2)s1 +CCOC(=O)c1c(C)[nH]c(C(=O)NCC(O)c2ccco2)c1C +Cc1noc(C)c1S(=O)(=O)Nc1ccc(OCC#N)cc1 +CC1CN(CC(=O)NC(C)c2ccco2)CC(C)O1 +Cc1ccc(-n2nc(C)c(C(=O)N3CCOCC3C)n2)c(C)c1 +COc1cccc(CNC(=O)CS(=O)(=O)c2ccccn2)c1 +NC(=O)c1ccc(NC(=O)COc2cccc(Cl)c2)cc1 +CN(C(=O)c1cccn2nccc12)C1CCCCC1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N1CCC(O)C1 +CN(C)c1cccc(C(=O)N2CCOC(C3CCCO3)C2)c1 +CC(C)CC(NC(=O)c1cccc(Br)c1)C(=O)N(C)C +Cc1ccc(CNC(=O)CSc2nc(-c3ccccc3)no2)cc1 +CCCC(C)(NC(=O)c1ncccc1O)C(=O)OC +COCCN(Cc1cnn(C)c1)C(=O)Cn1cc(C)c(=O)[nH]c1=O +Nc1ccc(NCCS(N)(=O)=O)c(C(F)(F)F)c1 +O=C(Nc1cccc(-c2ncco2)c1)C1COc2ccc(F)cc2C1 +COCCn1cc(O)c(=O)cc1CN1CCN(CCO)CC1 +CCCc1nnc(NC(=O)NC(C)c2cc(C)sc2C)s1 +Cc1ccc2c(c1F)CCNC2C1COc2ccccc2O1 +COc1ccccc1CCC(=O)Nc1cccnc1 +CC(C#N)Sc1nnc(COc2ccccc2Cl)n1C1CC1 +C=CCN(C(=O)COc1ccccc1C#N)c1ccccc1 +O=C(c1cccnc1)N1CCc2c1cccc2C(F)(F)F +COCCc1ccc(OS(=O)(=O)c2ccc(F)cc2F)cc1 +CCNC(=O)CNC(=O)NC(c1ccccc1)C1CCCC1 +Cc1ccccc1NC(=O)c1ccc(-n2ccnc2C)nn1 +COc1ccc(-c2cc(CC#N)c(C3CC3)o2)cc1F +CCOc1cccc(C(=O)Nc2cccc(C(=O)NC)c2)c1 +CNC(=O)c1cccc(NC(=O)Cc2csc(C)n2)c1C +CCC(CO)NC(=O)Nc1ccc(CN2CCCC2=O)cc1 +Cc1cc(C)n(-c2ccc(Cl)c(C(=O)OC(C)C)n2)n1 +COc1ccc2c(CSc3nnnn3C)cc(=O)oc2c1 +Cc1noc(C)c1CCCNC(=O)Nn1cnc2ccccc21 +CC(Oc1cccc(N)c1)C(=O)Nc1cc(Cl)cc(Cl)c1 +Cc1ccc(CCN(CC2CCCO2)C(=O)c2cc[nH]c(=O)c2)cc1 +O=c1c2c(O)cc(O)cc2oc2c(O)ccc(O)c12 +CCCNc1ccc(C(=O)N2CCC(Oc3cccnc3)CC2)cn1 +O=C(NCC1CCC(CNC(=O)c2ccon2)CC1)c1ccon1 +CCC(CO)Nc1ncc(Br)cc1C#N +CC1CCCN(S(=O)(=O)c2cccc(C#N)c2)C1 +CC(C)N(C(=O)c1cc(F)c(F)cc1Cl)C1CCC1 +COc1cccc(NC(=O)c2oc3c(c2C)-c2[nH]ncc2CC3)c1 +CCCS(=O)(=O)NCC#Cc1ccc(C(C)=O)cc1 +CC(C)N(CCCO)C(=O)Cc1ccc(O)cc1 +CCn1cc(C(=O)OCc2nc(-c3ccccc3)no2)cn1 +CN(Cc1cnn(C)c1)C(=O)c1ccccc1Cn1cccn1 +CCc1noc(CC)c1CC(=O)NC(C)(C#N)CC +O=C(CN1CCCCC1=O)Nc1nc(-c2ccc(Cl)cc2)cs1 +CCNC(=O)c1c(C)nc(N)nc1-c1ccc(F)cc1 +CC(C)CC(C(=O)N1CCNC(=O)CC1)N1CCCCC1=O +COc1ccccc1NC(=O)c1ccccc1-n1cnnn1 +CCC(=O)Nc1ncc2c(n1)CC(c1ccccc1Cl)CC2=O +Cc1cccn2cc(COC(=O)c3ccc(S(N)(=O)=O)cc3)nc12 +CC(C)(CNC(C(=O)NC1CC1)c1ccccc1)N1CCOCC1 +CNC(=O)C1CCCN(C(=O)c2scnc2C2CC2)C1 +COc1ccc(NC(=O)COc2ccccc2Cl)c(N)c1 +COc1ccc(CN(CC(F)F)C2CC2)cc1SC +COc1cc(O)cc2c1CCNC2c1cccc(O)c1 +CC(=O)c1ccc(OCC(=O)Nc2ccc(OC(C)C)cc2)cc1 +CCc1cc2c(=O)c(-c3nncn3-c3ccccc3)coc2cc1O +CCn1nc(C)c(CN(CCC#N)Cc2ccccn2)c1C +CN(C)C(=O)C(C)(C)NCc1cccc(C(=O)Nc2ccccc2)c1 +CC(=O)Nc1ccc(-c2cn3c4c(sc3n2)CCCC4)cc1 +O=C(Cc1cccs1)N1CC2OCCN(Cc3ccccc3)C2C1 +NC(=O)c1c(N)c(C(=O)c2ccc3c(c2)CCCC3)n2ccccc12 +COc1ccc(CN(C)C(=O)C(C)c2cccs2)cc1F +COc1ccc(CNC(=O)N2CCCCCC2c2ccco2)cn1 +CNC(=O)c1cccc(C(=O)OCc2cccnc2)c1 +CC(=O)Nc1ccc(C(=O)NCCNC(=O)CC(C)(C)C)cc1 +CC(C(=O)N1CCCCC1)n1nnc2ccccc2c1=O +Cn1cnc(CNC(=O)N2CCc3ccc(F)cc3C2)n1 +CCNC(=O)C(C)NC(CC)c1ccc(F)cc1 +CCN(C(=O)c1ccc[nH]1)C(c1ccc(OC)cc1)c1cccnc1 +CC(C)CNC(=O)N1CCCC(CC(=O)N(C)C2CC2)C1 +CCCNC(=O)c1ccc(=O)n(Cc2cccc(F)c2)n1 +Cc1noc(C)c1CN1CCCC(c2noc(C3CC3)n2)C1 +COC(=O)c1cccc(NC(=O)Cn2cc(N)cn2)c1 +CC=CCN1CCCn2c1nc1c2c(=O)n(CC=CC)c(=O)n1C +CC(=O)N1CCCC1C(=O)N(C)Cc1ccc(F)cc1 +Cc1csc(NC(=O)c2ccc(-n3ccnc3)nc2)n1 +COc1ccc(C(=O)OCC(=O)Nc2cccc(C)c2)cc1OC +CC(=O)Nc1ccc(OC(=O)C23CC4CC(CC(C4)C2)C3)cc1 +O=C(NC1CCCC(O)C1)C12CC3CC(CC(C3)C1)C2 +CC(C)Cn1ncc(C(=O)N(C)c2ccc3c(c2)CCO3)c1C(F)F +CC1CCCCC1N(C)C(=O)c1cccc(C#N)c1 +CC(Sc1nncn1C)C(=O)NC(C)(C)c1cccc(F)c1 +Cc1nc(C)c(CC(=O)Nc2ccccc2C(C)C)c(=O)[nH]1 +Cc1ccc(CCC(=O)N2CCN(Cc3cc(C)on3)CC2)cc1 +CC(C)CN1CC(C(=O)Nc2nc3c(s2)CCCCC3)CC1=O +COc1ccc(OCC(=O)N(C2CC2)C2CCN(C(C)=O)CC2)cc1 +CCOC(=O)CNC(=O)c1ccc(Br)cc1C +COC(=O)C1CC(NC(=O)c2nc3c(s2)CCCC3)CN1C +CNC(=O)c1cccc(NC(=O)COc2cccc3c2CCC3=O)c1 +COc1ccc(CCC(=O)N2CC(=O)Nc3ccccc32)cc1 +COc1cc(=O)n(Cc2nc(CC(C)C)no2)cc1Br +Cc1ccc(NC(=O)NCCC(=O)N(C)C)c(F)c1 +N#Cc1ccc(Oc2cccc(NC(=O)C3(C#N)CCC3)c2)nc1 +Cc1cc(NC(=O)N(Cc2ccc(C#N)cc2)C(C)C)no1 +CCCc1c(C(=O)NCC(N)=O)[nH]c(C)c1C(=O)OC +Cn1c(-c2ccccc2N)nc2cc3c(cc21)OCCO3 +CCOCC(=O)NCCc1nc2ccc(F)cc2[nH]1 +O=C(Nc1cccc(O)c1)c1ccc(NC(=O)c2cccs2)cc1 +Cc1ccc(S(=O)(=O)Nc2ccc(N)cc2Cl)cc1C +O=C(OCc1ccc(-n2cccn2)cc1)C1CCOCC1 +CC(C)c1cc(C(=O)NCC2CCc3ccccc3O2)on1 +CC(C)c1ccc(N(C)C(=O)c2ncn(-c3ccccc3)n2)cc1 +CC(C)c1ccc(-c2nc(C(=O)N3CCNC(=O)C3)cs2)cc1 +CC(O)CNS(=O)(=O)c1c(Cl)cccc1Cl +Cc1cc(C(C)NC(=O)N2CCC(n3cncn3)CC2)c(C)s1 +Cn1c(COC(=O)c2ccccc2C(F)(F)F)cc(=O)n(C)c1=O +N#Cc1ccccc1NC(=O)CS(=O)(=O)c1ccccc1 +CC(=O)c1cccc(NS(=O)(=O)c2cc(F)ccc2F)c1 +O=C(NCCCc1nc2ccccc2[nH]1)c1cc2cccnn2n1 +CCC(C)C(=O)NCc1ccc(CS(=O)(=O)NC)cc1 +OCC1CN(c2nccc(C3CCCC3)n2)CC1CN1CCOCC1 +CC(=O)NCCC(=O)Nc1ccc(CNC(N)=O)cc1 +Cc1cccc(C(=O)N2CCCC(c3nc4ccccc4[nH]3)C2)c1C +COc1ccccc1C(O)CCC(=O)N1CCC(C)CC1 +N#Cc1nnn(-c2cccc(Cl)c2)c1C1CCC1 +Cc1ccc(C#N)cc1NC(=O)NCC(=O)Nc1ccc(F)cc1 +COc1ccc(OC)c(N2CCN(C(=O)C(C)(C)C)C(C)C2=O)c1 +COC1COC2(CCN(C(=O)Cc3ccsc3)CC2)C1 +CCCNC(=O)Cc1csc(NC(=O)c2ccc(F)cc2)n1 +CCCS(=O)(=O)N1CCc2ncc(Cn3cccn3)n2CC1 +Cn1ccnc1SCc1cc(Cl)c2c(c1)OCCO2 +CSc1ncc(-c2c(C#N)c(N)nc3c2C2CCC(C3)N2C)cn1 +O=C(Cc1ccc(O)cc1)NCCNC(=O)c1ccc(Cl)cc1 +CC(C)(Oc1ccc2c(c1)CCC2)C(=O)N1CCCC2(CCOC2)C1 +O=C(COCC(F)(F)F)N1CCCC(c2nnc3ccccn23)C1 +CN(C)c1ncccc1NC(=O)c1cccc(Cl)c1 +O=C(Cc1ccc(F)c(F)c1)NCC(=O)NC1CCCCC1 +COC(=O)c1ccccc1NC(=O)Cn1cnc2onc(C)c2c1=O +Cc1cc(=O)[nH]cc1C(=O)NC(c1ccc(Cl)cc1F)C(C)C +CCOC(=O)c1cn[nH]c1S(=O)(=O)NCC(C)O +COC(=O)N1CCCC(C(=O)Nc2ccc(C(C)=O)c(C)c2)C1 +COC1CCCN(C(=O)Nc2ccc(OC(F)(F)F)cc2)C1 +COc1ccc(CNC(=O)Nc2ccc3nc(C)oc3c2)cc1OC +CCn1ncc(CN(C)S(=O)(=O)c2ccc(C(C)C)cc2)c1C +Cc1ccc(NC(=O)c2cc(C(F)(F)F)n(C)n2)cc1F +CC(C)NC(=O)N1CCC2(C1)CN(c1cnn(C)c1)C(=O)CN2C +C#CCOC(=O)Cc1c(C)nn(-c2nc(C)cc(C)n2)c1C +CCCN(Cc1ccsc1)C(=O)C1CCN(S(C)(=O)=O)CC1 +Cc1ccn(-c2ccc(NCCNC(=O)Cc3ccccc3)nn2)n1 +O=C(Nc1cccc(-c2nc[nH]n2)c1)c1csc(-c2ccoc2)n1 +CC(=O)N1c2ccccc2CC1C(=O)Nc1cccc2c1CCCC2 +O=C(NCC(O)c1cccc2ccccc12)c1c(F)cccc1F +Cc1cc(NC(=O)Cc2c(F)cccc2Cl)n(CCC#N)n1 +CCOC(=O)C1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1 +CC(=O)N1CCN(C(=O)c2cc3scnc3[nH]2)CC1 +Fc1ccc(Cc2nc3nccc(-c4cccnc4)n3n2)cc1 +CN(C)S(=O)(=O)c1cccc(C(=O)Nc2cc(F)cc(F)c2)c1 +Cc1ccccc1C(=O)NCC(=O)N1CCNC(=O)C1 +COc1ccc2sc(C(=O)NCc3n[nH]c(=O)[nH]3)c(C)c2c1 +O=C(CCc1ccccc1)N1CCN(C(=O)c2ccco2)CC1 +CCOC(=O)c1ccc(OS(=O)(=O)c2ccccc2)cc1 +CCOC1CCN(C(=O)C2CC=CC2)C1Cc1ccncc1 +O=C(CSc1nc(-c2ccccc2)n[nH]1)N1CCc2ccccc21 +O=C(CNC(=O)c1ccccc1)NC1CCOc2c(Cl)cccc21 +Cc1ccc2ncc(C(=O)Nc3ccc(C#N)cc3)n2c1 +O=S(=O)(c1ccc(CSc2nnnn2C2CC2)cc1)C(F)F +CC(C(N)=O)c1cccc(C(=O)c2ccccc2)c1 +COc1ccc2cc(C(=O)NCc3ccccc3)c(=O)oc2c1 +Cc1cc(-c2nnc(CN3CCc4cc(F)ccc4C3)o2)c(C)o1 +CCc1nc(CN(C)C(=O)CN2CCC(C)C2=O)no1 +Cc1cnn(CCC(=O)NCCc2nnc3n2CCCCC3)c1 +COC(=O)C(C)N1CCC(N(C)C(=O)OC(C)(C)C)CC1 +Nc1ccc2onc(CC(=O)Nc3ccncc3)c2c1 +Cc1csc(=O)n1CCC(=O)NCCNC(=O)c1cccnc1 +COc1ccccc1OC1CN(C(=O)C2CC(=O)N(C(C)C)C2)C1 +CCOc1ccccc1NS(=O)(=O)c1cnn(CC)c1 +CC(=O)c1cccc(S(=O)(=O)NC2CCOCC2)c1 +CSc1nc(C(=O)OCCNc2cccnn2)c2ccccn12 +CCc1cccc(CC)c1NC(=O)c1cccc(NC(C)=O)c1 +CC(C)N(C(=O)CSc1nnc(-c2ccccc2)n1C)C(C)C +Cc1cccc(-n2ccc(NC(=O)c3ccccc3F)n2)c1 +Cc1cc(C)c(C(=O)NCc2cccc(C(=O)N3CCCCC3)c2)[nH]1 +CNC(=O)c1cc(S(=O)(=O)Nc2cc(Cl)ccc2O)cs1 +O=C(c1cc(-c2ccccn2)n[nH]1)N1CCCC2(CCCO2)CC1 +CCNC(=O)c1ccc(CNC(=O)Nc2ccccc2)cc1 +Brc1ccc2[nH]c(NCCCN3CCOCC3)nc2c1 +COC(=O)CCN(C)C(=O)c1cc(Br)ccc1Cl +COCc1nc(CNC(=O)Nc2cccc(C(F)(F)F)c2F)no1 +Cc1cc(C(=O)CSc2nncn2C2CC2)c(C)n1C1CC1 +COc1ccc2c(c1)OCC(CNC(=O)C1(Cn3cccn3)CC1)C2 +Cc1cccc(CNC(=O)CCCc2cc(F)ccc2F)n1 +COCCC(=O)N1CCC2(CCCC(=O)N2C)CC1 +COc1ccc(NC(=O)Nc2cccc(C)n2)cc1 +CCOC(=O)CN(CC)C(=O)c1ccc(NC(C)=O)cc1 +CC1CN(CCC(N)c2ccccc2Cl)C(C)CO1 +CC(O)CN(C)c1ccc(S(=O)(=O)C(F)F)cc1 +CCCn1nc(C(=O)N2CCCC2C2CCCCC2)ccc1=O +Cc1ccsc1CNC(=O)c1cc(C)n(Cc2ccco2)c1C +O=C(NCC(O)c1ccco1)Nc1ccccc1OC(F)(F)F +CCc1cccc(NC(=O)CNC(=O)c2c[nH]c3ccccc3c2=O)c1 +CCCCN(CC)C(=O)c1cc(NC(=O)CC)ccc1O +OC1COC2C1OCC2n1nnnc1SCc1ccco1 +CCCn1nc2c(cc1=O)CN(c1nn3cc(C)nc3s1)CC2 +CC1COCC(C)N1C(=O)COc1cccc(C(N)=O)c1 +NC(C(=O)OCc1c(F)cccc1Cl)c1ccccc1 +Cc1cc(C)cc(C(NC(=O)NCC2(CO)CC2)c2cccnc2)c1 +CCNC(=O)c1ccc(CNC(=O)c2ccccc2OC(F)F)cc1 +CCC(C)NC(=O)NC1CC(=O)N(c2ccc(OC)c(OC)c2)C1 +CCNC(=O)CNCc1cccc(-c2ccccc2)c1 +O=C(NCC(O)CN1CCOCC1)Nc1ccc(-n2nccn2)cc1 +COc1cc(CNC(=O)c2cc(F)cc(F)c2)ccn1 +COC(=O)c1cccc(CCNC(=O)C(C)c2cccnc2)c1 +CCN(CC(=O)NC(C)C)C(=O)c1sc(C)nc1C +O=C(Nc1ccc(F)c(Cl)c1)Nc1cc(N2CCCCC2)ncn1 +Cc1cc(CN2CCN(C(=O)c3ccc(C)[nH]c3=O)CC2)on1 +COC(=O)C(C)n1ccnc1-c1cccc(Br)c1 +Cc1nnc(COc2cc(C(F)(F)F)cc(C(F)(F)F)c2)o1 +CN1C(=O)CC(C(=O)Nc2ccccc2)c2ccccc21 +COc1cccc(C(=O)CCc2nc(C)c(C)s2)c1 +CCCCNC(=O)CN1C(=O)COc2ccc(C(C)=O)cc21 +COc1ccc(C(C)C)cc1C(C#N)C(=O)C1CC1 +Cc1nc(C)c(C(=O)NCc2nc3ccccc3s2)s1 +CCOC(=O)CC(C)CNC(=O)c1cnc2[nH]nc(C)c2c1 +Cc1nccn1Cc1ccc(NC(=O)Cc2cccc(Cl)c2)cc1 +CNC(=O)c1cnc(C=Cc2cc3cc(F)ccc3o2)[nH]c1=O +CCCCNC(=O)CN(C)c1nc(C(C)(C)C)nc2c1cnn2C +COCCN(CC(C)C)C(=O)Cn1c(=O)[nH]c2ccccc21 +CCC(CC)NC(=O)C1CC(=O)Nc2ccccc21 +CCCOC1CCCN(Cc2ncccc2C(F)(F)F)CC1 +CCc1cc2c(cc1C(=O)CCN1CCOCC1)OCCO2 +Cc1ncnc(NC(C)CCCC(C)(C)O)c1C +CCn1cnnc1CCNC(=O)c1cnc(Nc2ccccc2)nc1 +CCn1c(C)cc(=O)c2cc(C(=O)NCc3cccnc3)ccc21 +CCc1noc(C(C)NC(=O)Cc2nc3cc(Cl)ccc3[nH]2)n1 +CC(C)Oc1ccc(OC2CC2)c(S(N)(=O)=O)c1 +CCOCc1ccc(CNC(=O)c2cccc(OC)c2F)cc1 +Cc1nnc2sc(-c3ccccc3C(F)(F)F)nn12 +CSc1nccnc1CN1CCCC1CNC(=O)OC(C)(C)C +CNC(=O)c1cccc(C(=O)N=c2[nH]ncn2C)c1 +Cc1cnc(N2CCN(CC(=O)NCc3ccccc3F)CC2)s1 +Cc1ccc(NC(=O)CCNC(=O)N2CC(C)OC(C)C2)nc1 +CCOc1ccccc1C1CCN(C(=O)c2cnn(C)c2C)CC1 +CC(=O)N(Cc1ccco1)Cc1cc2ccc(C)cc2[nH]c1=O +Cc1nc(COc2cccc(-c3nnco3)c2)cs1 +COCCOc1ncccc1C(=O)NCc1c(C)cc(C)[nH]c1=O +COc1nn(C)cc1C(=O)NCCn1ccc(-c2cccs2)n1 +O=C(NCCO)Nc1cccc(-c2cn(Cc3ccccc3)nn2)c1 +COc1ccccc1OC1CN(C(=O)c2cnc(SC)nc2)C1 +CCN(Cc1ccccc1)C(=O)Cc1cn(CC)c2ncccc12 +COC(=O)COC(=O)C1CCCN(S(=O)(=O)c2cccnc2)C1 +Cc1cc(-n2cc(C(=O)N3CCc4ccccc4C3)nn2)ccc1F +CC(OCC1CC1)C(=O)Nc1cccc(Oc2ccncc2)c1 +O=C(Cc1noc2ccccc12)N(Cc1ccccc1F)C1CC1 +O=C(Cn1nc2ccccn2c1=O)Nc1cccc(Cn2ccnc2)c1 +Cc1noc(C(C)OC(=O)c2cn(Cc3ccccc3)nn2)n1 +CCc1noc(CN(C)C(=O)c2ccccc2-c2ncn[nH]2)n1 +CCOC(=O)c1cccnc1N1CCc2ccccc2C1 +O=C(Nc1ccccc1)C1C2CC3OC(=O)C1C3C2 +Cc1cc(CN(C)C(=O)c2ccc(NC(=O)NC(C)C)cc2)no1 +CCn1nccc1C(=O)NCc1ccc(Cl)cc1 +c1csc(C2CN(Cc3ccc(-n4cncn4)cc3)CCO2)c1 +CC(C)S(=O)(=O)NCc1cc(F)ccc1Br +COCCNc1nnc(-c2c(C)cc(C)n(C)c2=O)s1 +CCc1nnc(NC(=O)c2cc3c(C)nc4ccccc4c3o2)s1 +C=CCOC(C)C(=O)NCc1nc2ccccc2s1 +CCCc1cc(=O)[nH]c(SCc2ccc(C(N)=O)cc2)n1 +Cc1cc(C(=O)Nc2ccc(S(=O)(=O)C3CCCC3)cc2)on1 +Cc1nc2ccccc2n1CCNC(=O)CCOc1ccccc1 +Cc1sc(=O)n(CC(=O)NC(C)Cc2c(F)cccc2F)c1C +CCOC(=O)c1sc2[nH]cc(C(=O)OCC)c(=O)c2c1C +Cc1ccc(F)c(OCC(=O)Nc2nc(C)cs2)c1 +CC(=O)N1CCN(Cc2nc3c(s2)CCc2ccccc2-3)CC1 +CCC(=O)N1CCN(c2cc(N3CCOCC3)cnn2)CC1 +COc1ccc(S(=O)(=O)N(CC2CCOC2)C2CC2)cc1Cl +CC(Oc1cccc(Cl)c1)C(=O)NCC(=O)C(C)(C)C +Cc1cc(C)cc(NC(=O)Cn2nnc(-c3ccccc3)n2)c1 +Cc1nccn1-c1ccc(CNC(=O)c2cc(C(N)=O)cs2)cn1 +COC(=O)c1n[nH]cc1-c1c(C#N)c(N)nc2c1CCCCC2 +CCOc1ccccc1C(=O)Nc1cccn2nc(CC)nc12 +Cc1nc(C2CCCN2C(=O)c2ccc(N3CCCC3)nn2)no1 +O=C(c1ccc(=O)oc1)N1CCN(c2ccc(F)cc2)CC1 +CCc1ccc(C(=O)OCC(=O)N(CC)CC)cc1 +Nn1c(SCc2cc(Cl)cc3c2OCOC3)nncc1=O +Fc1ccccc1CN1CCN(c2ccc3nnnn3n2)CC1 +COCC1CCCN1Cc1cc(=O)c2cc(F)ccc2[nH]1 +CSc1nc(C(=O)NCC2CCC2)c2ccccn12 +Cc1nn(C)c2nc(N3CC4CC(C3)c3cccc(=O)n3C4)sc12 +CCCn1c(SC(C)C(C)=O)nc2cc(S(N)(=O)=O)ccc21 +CC(=O)NC1(C(=O)OCc2noc(C(C)(C)C)n2)CCCCC1 +COc1ccc(F)cc1NC(=O)N1CCN2C(=O)NCC2C1 +CC(C)CCNC(=O)CC1NC(=O)c2ccccc2NC1=O +CCCn1nc(C(=O)Nc2ccc(F)cc2F)ccc1=O +COc1ccc(F)cc1NC(=O)C(C)NC(=O)Nc1ccccc1 +CSc1cc(C(=O)NCc2nc(-c3ccccc3)cs2)ccn1 +Cc1nc(C)c2c(n1)OC(Cn1c(=O)c(C)nc3ccccc31)C2 +O=C(NCc1ccc(Cn2ccnc2)cc1)c1ccc2c(c1)CCO2 +COc1ccccc1-n1cnnc1SCCC#N +CCC(C)C(NC(=O)c1ccc(F)cc1Br)C(N)=O +CCc1ncc2c(n1)CN(C(=O)c1ccc(-c3ccc(C)cc3)cc1)C2 +Nn1c(SCC(=O)NC2CCCCC2)nnc1-c1cccnc1 +CNC(=O)c1cccc(CCNC(=O)N(C)Cc2cnn(C)c2)c1 +CC(C)NC(=O)c1cn2c3c(ccc(Cl)c3c1=O)OCC2 +CC(C)CN(CC(N)=O)C(=O)c1cnc(C2CCCO2)s1 +CCCOc1cc(NCc2ccncc2)nc(C2CC2)n1 +Cc1ccc(N2CCCC(NCC(=O)NCc3cccs3)C2)nn1 +Cc1nc(NCCNC(=O)Nc2cccc(F)c2C)cc(N(C)C)n1 +N#Cc1c(SCC(N)=O)nsc1SCC(N)=O +CCOC(=O)CC(C)CNC(=O)Nc1ccsc1 +O=S(=O)(Nc1ccc2c(c1)CCC2)c1ccc(F)cc1F +O=C(Nc1ccc(-n2ccnc2)nc1)c1cccc(N2CCCC2=O)c1 +CN(C1CCCN(C(=O)Cc2ccc(F)c(F)c2)C1)S(C)(=O)=O +CCC(C)NC(=O)NCC(O)c1ccccc1Cl +CC(C)COCCNC(=O)Nc1ccc(F)c(C#N)c1 +CCOC(=O)c1cn(Cc2ccc(C)cc2)c2ccc(F)cc2c1=O +Cc1ccc(-n2ncc(C#N)c2C)c(Br)c1 +Cc1cc(NC(=O)c2ccc(=O)[nH]n2)ccc1N1CCCC1=O +CN(C)c1ccc(NC(=O)Cn2c(=O)[nH]c(=O)c3ccccc32)cn1 +COCCN1CCN(C(=O)NCc2ccc3c(c2)CCC3)CC1=O +Cc1noc(C)c1CNc1ncc(F)c(N(C)C)n1 +Cc1noc(C)c1CC(=O)NC1CC2CCC1(C)C2(C)C +O=C(Nc1ccncc1)NC1CCc2c(Cl)cccc21 +COc1ccc(OC)c2c1CCNC2c1ccc(C)s1 +CCN(C(=O)NCc1ccc(N2CCCC2=O)cc1)C1CCCC1 +CC(NC(=O)NCc1ncn(C)n1)c1ccc(-c2ccncc2)cc1 +CC(C)(C)n1nc(C(=O)NCC(=O)NC2CC2)cc1C1CC1 +N#Cc1ccccc1OCCn1nnc2ccccc2c1=O +CCc1ccc(OC)c(-c2cnn(CCC#N)c2)c1 +Cc1cc(NC(=O)CSc2ccccc2O)n(C(C)(C)C)n1 +Cc1ccnc2nc(C(=O)NCc3ccc4c(c3)OCCO4)nn12 +CCN(CC)c1ncc(C(=O)Nc2cccc(C)n2)c(N)n1 +Cc1noc(C2CCCN(Cc3nc(-c4cccnc4)no3)C2)n1 +O=C(NCc1ccnc(N2CCOCC2)n1)c1ccc2c(c1)OCO2 +CC(c1ccco1)N(C)C(=O)c1ccnc2ccccc12 +Cc1cccc(C(=O)Nc2c(C)cccc2N)c1O +CCOC(=O)c1c(C)[nH]c2cc(Cl)ccc2c1=O +Cc1nnc(SCCCOc2ccc(C#N)cc2)c(C#N)c1C +CCC(C)NC(=O)C1CC(=O)N(c2cccc(C(C)C)c2)C1 +CC(C)(C)c1c(CO)nnn1Cc1ccccc1F +CC(=O)c1c[nH]c(C(=O)Nc2ccc3nc(C)oc3c2)c1 +NC(=O)c1cnc(-c2ccc(Cl)cc2Cl)nc1N +CC(=O)c1c[nH]c(C(=O)N2CCN(c3ccc(F)cc3)CC2)c1 +COc1ccc(OC)c(CNC(=O)c2cnc(C(C)C)nc2C)c1 +CCOC(=O)c1c[nH]c2c(C)ccc(Cl)c2c1=O +Cc1nnc(N(C(=O)c2cnccn2)c2ccccc2)s1 +CC(NC(=O)N1CCNC(=O)CC1)c1cccc(-n2cccn2)c1 +CCc1ccc(C(C)NC(=O)CS(=O)(=O)c2nccn2C)cc1 +O=S(=O)(N1CCCC(O)(CO)CC1)N1CCc2ccccc2C1 +COC(=O)C(C)Sc1nnc(C2CC2)n1C1CC1 +Cc1c(F)cccc1NCc1noc(C2COc3ccccc3O2)n1 +NC(=O)c1cccnc1N1CCC(CNC(=O)c2cccs2)CC1 +Cc1ccc(NC(=O)NCc2c(C)nn(C)c2C)cc1C +Cc1nnc(SC(C)C(=O)NCC(F)(F)F)s1 +O=C(C1CCC1)N1CC2CCC(C1)N(C(=O)c1ccc(F)c(F)c1)C2 +CCCNC(=O)c1cccc(C(=O)NC2(C(N)=O)CCCCC2)c1 +CC(=O)Nc1nc(CC(=O)N2CCC(C)CC2)cs1 +COCCOC(=O)Cn1c(-c2ccccc2)ccc(C#N)c1=O +COc1ccc(CC(=O)Nc2nnc(S(C)(=O)=O)s2)cc1 +CC1CN(CCCNC(=O)C(C)CC2CCCC2)CC(C)O1 +CC(C)CNC(=O)Cc1cc(-c2ccc3c(c2)CC(C)O3)on1 +CCOc1ccccc1C(=O)N1CCN(C(=O)NC2CCCC2)CC1 +Cc1c(F)cccc1NC(=O)c1cc(N2CCCC2=O)ccc1Cl +CCOC(=O)c1nn(CCc2ccccc2)c2[nH]c(=O)cc(C)c12 +CCc1ccc(C(=O)CCC(=O)N2CCCC2C(=O)N(C)C)cc1 +Cc1ccc(CNS(=O)(=O)N2CCCCC2)s1 +COc1c(C(=O)C(C)N)ccc(C)c1Br +CC(=O)Nc1cc(NC(=O)NCC(O)c2ccco2)ccc1C +COC(=O)C(c1ccccc1)N(C)Cc1ccco1 +Cc1ccc(OCC(=O)NCC(O)c2ccccc2Cl)cc1C +CC(C)CC1(CNC(=O)CN(C)C(N)=O)CCCC1 +CCc1nc(C)sc1C(=O)N1CCN(C(C)C)C(CC)C1 +NC(=O)NCc1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1 +O=C(CCCC1CCCC1)NCc1cn(-c2ccccc2)nn1 +COc1ccc(C)cc1NS(=O)(=O)c1cccc(O)c1 +CCNC(=O)c1cccc(CNC(=O)c2ccc3ccccc3n2)c1 +CCCCN1CCN(S(=O)(=O)c2ccccc2F)CC1 +O=C(CCc1ccc(F)cc1)Nc1sccc1C(=O)NC1CC1 +NC(=O)CN(Cc1ccccc1)S(=O)(=O)c1ccccc1F +CC(CNC(=O)c1cncc(Br)c1)N1CCOCC1 +COCc1nnc(C(=O)N(C)Cc2cnn(-c3ccccc3C)c2)o1 +Cc1nn(-c2ccccc2)c(C)c1SCC(=O)Nc1nccs1 +O=C1CCC(C(=O)Nc2ccc(OC(F)F)cc2)N1 +O=C(NCC1COCCO1)c1ccc(Br)cc1 +NC(=O)C1CCN(c2ncc(N)cc2Br)CC1 +O=C(c1ccco1)N1CCN(S(=O)(=O)NCc2ccccc2)CC1 +O=C(NCc1ccccc1Cn1cccn1)Nc1cccnc1 +C=CCNS(=O)(=O)c1ccc(OCC)c(C(C)C)c1 +Nc1ccc(C(=O)OCC2CCCCO2)c(Cl)c1 +CC1(C)CNC(=O)c2nc(Cn3ccc4ccccc43)[nH]c2C1 +CCCC(=O)N1CCN(c2c(C)nn(-c3ccccn3)c2C)CC1 +CCN(Cc1cnn(C)c1)S(=O)(=O)c1ccc(C)c(C)c1 +N#CC(NC(=O)c1cccc(C(N)=O)c1)c1ccc(F)cc1F +O=C(CCn1ccccc1=O)NCCCn1cccn1 +O=C(NCCO)NCc1ccc2c(c1)OCCO2 +O=C(NCc1ccc(O)c(F)c1)c1cc(F)c(F)c(F)c1 +NC(=O)Nc1cccc(C(=O)NCc2ccc3c(c2)OCCO3)c1 +CCOc1ccccc1OCCN1CCC(N2CCOC(C)C2)CC1 +CCOCC(=O)Nc1cc(Br)ccc1N1CCOCC1 +Cn1cnn(CC(=O)Nc2cc(-c3c(F)cccc3F)[nH]n2)c1=O +COc1cc2c(c(OC)c1OC)CCC(C)CC2=O +Cc1cccc(Nc2ncnc(NC(C)C)c2N)c1C +COc1c(Cl)c2c(c(OC)c1OC)CNCC21CC1 +O=C(Nc1cnn(Cc2ccccc2)c1)N1CCCC1 +CC(=O)c1cccc(NC(=O)c2cccnc2N2CCOCC2)c1 +Cc1ccc(C(=O)NC(C)C(=O)NCC(F)(F)F)n1C +OCC1NCCc2c(O)ccc(Br)c21 +COc1cc(C)ccc1OC(=O)C1CCCN(C(=O)C(C)(C)C)C1 +CCCOc1cccc(CNc2cnn(-c3ncccn3)c2)c1 +CCc1nc(COC(=O)C2COc3ccc(F)cc3C2)cs1 +COC(=O)C(C)(NCC(F)(F)F)c1ccc(OC)cc1 +CCC(C)NC(=O)CCC(=O)c1cc(C)sc1C +C=CCN1CCN(C(=O)c2cc3cccc(OCC)c3oc2=O)CC1 +COCCNC(=O)c1ccc(N)c(OCc2ccccc2)c1 +CC(C)c1nc(N2CCCCCC2)sc1CO +COC(=O)CN(c1cccc(C)c1C)S(C)(=O)=O +Cc1ccccc1-n1nc(-c2ccccc2)nc1CCc1nncn1C +COc1ccc(S(=O)(=O)N(Cc2ccccn2)C2CC2)cc1C +CNC(=O)c1cccc(NC(=O)N2CCc3ccccc3C2)c1C +Cc1cc(C(C)NC(=O)CCc2ccncc2)c(C)s1 +Cc1ccc(-c2noc(-c3cccc(-n4nnnc4C)c3)n2)nn1 +C#CCNC(=O)C1CCCCN1C(=O)OC(C)(C)C +COc1ccc2c(c1OC)C(c1cncn1C)NCC2 +CN(C)C(=O)CCNC(=O)Nc1cccc(N2CCCCC2)c1 +Clc1ccccc1-n1cc(NCC2=CCCOC2)cn1 +C#CCN(CC(F)(F)F)C(=O)c1cccc(F)c1OCC +COC1CCCC(OC(=O)CCSc2ccccc2)C1 +CCOCCCC(=O)Nc1ccc(C(=O)NC)c(Cl)c1 +COCc1ccc(C(=O)N(C)CCOc2ccc(C)cc2)o1 +COC(=O)c1ccc(CSc2nnc3ccc(N)cn23)cc1 +CC(=O)Nc1ccc(OC(=O)c2cn(C)c3ccccc23)cc1 +CCOC(=O)c1nc(C2CC2)n(-c2ccccc2)n1 +CCCC(=O)Nc1ccc(CNC(=O)c2ccc(F)nc2)cc1 +CCCc1nc2ccccc2n1Cc1nc2ccccc2n1CCO +O=C(Cn1cnc2ccccc21)NCC#CCOc1cccnc1 +CC(C)c1noc(CCNS(=O)(=O)c2cccc3ccccc23)n1 +c1cnc(N2CCCC3(CC(OCc4cccnc4)CO3)C2)nc1 +COc1cc(OC)c(NC(=O)Cc2cccs2)cc1NC(C)=O +CC(=O)N1CCCN(S(=O)(=O)c2cc(F)cc(F)c2)CC1 +O=C(CCn1nc2ccccn2c1=O)N1CCCC(c2ccn[nH]2)C1 +CCc1c(C)sc(NC(=O)COc2ccc(C)cc2C)c1C(N)=O +CC(=O)N1CCN(CC(=O)NC2CCC(C)CC2)CC1 +Cn1cnc(CNC(=O)c2occc2-c2ccccc2)n1 +Fc1ccccc1-c1nnc(CSc2nc3ncccn3n2)o1 +Cc1cc2cc(NC(=O)COCC3CC3)ccc2[nH]1 +O=C(CNC1(c2ccc(F)cc2)CCC1)NCc1ccco1 +CC1CCN(C(=O)c2cn3c(n2)CCC(c2ccc(F)cc2)C3)CC1 +CC(=O)NCC(=O)NCC(C)Cn1nc(C)cc1C +CC(=O)c1cccc(NC(=O)Cc2c(C)nn(C)c2C)c1 +Cc1ccccc1C(=O)N1CCN(Cc2ccccc2)C(C#N)C1 +CCOc1ccc(C(=O)CN2CCOCC2)cc1OCC +C=CCOc1cccc(NC(=O)N2CCCC(NC(C)=O)C2)c1 +CCOC(=O)c1ccc(C2Nc3ccccc3S(=O)(=O)N2)cc1 +O=C1c2ccccc2NC2(CCCCC2)N1CC1CCCO1 +COc1ccc(NC(=O)c2ccc(S(=O)(=O)N(C)C)o2)cc1 +Cc1ccc(CS(=O)(=O)N2CCc3ccc(=O)n(C)c3CC2)cc1 +COc1ccc2nc3sc(C(N)=O)c(N)c3cc2c1 +COc1ccccc1COC(=O)CCc1c(C)nn(C)c1C +Fc1ccc(C=CCN2CCOC3(CCC3)C2)cc1 +CCS(=O)(=O)c1ccccc1NC(=O)C(C)c1ccc(OC)cc1 +CCc1nc(COC(=O)c2cc(C(N)=O)cn2C)cs1 +Cc1ccc(C(O)CNc2c(C)cccc2C)cc1 +COC(=O)CCC(=O)c1cc(Br)ccc1OC +COC1CCC2C1OCCN2C(=O)Cc1csc2ccccc12 +CC1(C(=O)N2CCCC(CN3CCOCC3)C2)CC1(Cl)Cl +CNC(=O)c1[nH]cnc1C(=O)Nc1cccc(OC)c1 +CC(C)(C)C(NC(=O)Nc1ccc(Br)c(F)c1)C(N)=O +O=C(Nc1cc(-c2ccoc2)nn1-c1ccccc1)C1CCOCC1 +Cn1nc(C(=O)NCC2CCCO2)cc1OCC(=O)N1CCCC1 +CC(C)CNC(=O)c1c2c(nc3c1cnn3C(C)C)CCC2 +CS(=O)(=O)NCC1CCCN(C(=O)c2n[nH]c3ccccc23)C1 +CCCN(CCC)C(=O)C1CC(=O)N(Cc2ccccc2)C1 +COc1cccc(OC)c1C(=O)N1CCN(CCO)CC1 +COc1ccccc1C(CNC(=O)c1cccc(N(C)C)c1)OC +CC(=O)Nc1ccc(C(=O)N(C)c2ccccc2)cc1 +COCCOC(=O)C1CC(=O)N(c2cc(F)cc(F)c2)C1 +CCCC(CNC(N)=O)(CNC(N)=O)c1ccccc1 +CN(C)c1ccc(C(=O)OCC(=O)NC(C)(C)C)cc1 +Cc1cccc(C(=O)N2CCCC(CO)(Cc3ccccc3C)C2)n1 +COc1cc(CNC(=O)c2cnc(C)s2)ccc1OCC(N)=O +CC(=O)N1CCC12CCN(C(=O)c1cnccn1)CC2 +CNC(=O)c1ccc(NC(=O)CCc2ccsc2)cc1 +Cc1cc(C)n(CC2CCN(C(=O)CCc3ccccc3)CC2)n1 +CCCNc1ccc(C(=O)Nc2cc(C)on2)cc1 +CCCCN(CC(N)=O)c1cc(Br)ccc1CO +CCc1nc2n(n1)CCCC2NC(=O)NCCCn1nc(C)cc1C +CN(C)C(=O)Sc1ccccc1NC(=O)CC1(O)CCCCC1 +O=C(Cn1ccc2ccccc21)NCC1(c2ccccc2)CCOCC1 +CC(=O)c1c(N)c(-c2c(F)cccc2Cl)n(C)c1C +COc1ccc(-c2ccc(N)cc2OC)cc1OC +Cc1ccc(OCCC(=O)Nc2ccc3c(c2)OCC(=O)N3)cc1C +CN(C)c1nc(CNC(=O)c2c[nH]nc2-c2ccccc2F)cs1 +O=c1cc(C2CCC2)ncn1Cc1nc(CCc2ccccc2)no1 +O=C(Nc1ccccc1)C1CCCN1C(=O)c1ccccc1 +Cc1ccc(OCC(=O)Nc2ccccc2C#N)cc1C +CCCCn1c(-n2nc(C)c(C)c2C)nc2c1c(=O)n(C)c(=O)n2C +CC(=O)c1ccc(N2CCOCC2)c(-c2cc[nH]n2)c1 +CCc1cnc(N2CCN(S(=O)(=O)N3CCCC3)CC2)nc1 +CCOC(=O)c1cnn(Cc2ccc(F)cc2)c1C(F)(F)F +CCOc1ccc(N2C(=O)CN=C2Nc2ccccc2)cc1 +CCn1c(NCc2ccc(OC)cc2OC)nc2ccccc21 +Cc1c(-c2ccc(F)cc2)nn2c(-c3ccncc3)ccnc12 +CC1(C)CCC(CC(=O)NCCOC(N)=O)CC1 +Cc1ccc(CC(=O)NC(C)c2ccc(-n3ccnc3)cc2)cn1 +Cc1ccsc1C(=O)N1CCn2c(cccc2=O)C1 +Cc1cccnc1CNC(=O)NC(C)C(C)CO +Cc1ccc(S(=O)(=O)NC(C)C(C)C)cc1N +Cc1cc(C(=O)NCC(=O)NC(C)(C)C)n(C)n1 +CC(C)(C)c1ccc(C(O)CNCc2ccco2)cc1 +COc1ccccc1N1CCN(CCn2c(C)csc2=O)CC1 +COCC(=O)NCc1cccc(N2CCCCC2=O)c1 +COCC(=O)NCc1cc(=O)oc2c(C)cc(C)cc12 +CC(=O)c1c(C)[nH]c(C(=O)N2CCCC2c2c(C)n[nH]c2C)c1C +O=C1CN(C(=O)CN2CCN(c3ccc(F)cc3)C2=O)CCN1 +COC(=O)c1cc(-c2ccc(O)c(C(C)C)c2)nn1CCO +CCc1n[nH]c(C(=O)NC2CCC3CCCC32)c1C +CC1(C)Cc2nc3sc(C(=O)NCCO)c(N)c3cc2CO1 +CCN(CC)C(=O)CCCC(=O)Nc1cc(F)cc(F)c1 +O=C(OCCN1CCCC1=O)c1csc(-c2cccs2)n1 +O=C(NC(c1ccccc1)c1ccccn1)c1ccc2c(c1)COCO2 +O=C(CCC(=O)c1cccs1)NCc1[nH]ncc1Br +O=C(Cc1coc(-c2ccccc2)n1)N1CCOC2CCCCC21 +O=C(CSc1nnnn1-c1cccnc1)NC1CCCCCC1 +COC(=O)c1[nH]c2cc(OC)ccc2c1NC(=O)c1nonc1C +COc1ccc(OC)c(CN2CCN(c3ccccc3F)CC2)c1 +COc1ccc(CC(C)CN(C)C(=O)Nc2ccncc2)cc1 +CCn1ncc(C(=O)NC2CCc3cc(F)ccc32)c1C(F)(F)F +CCOCc1ccccc1CNC(=O)c1ccc(S(C)(=O)=O)cc1 +COC(=O)c1ccc(COC(=O)c2cc(C)oc2C)cc1 +O=C(C#CC1CCC1)NCc1ccc2c(c1)OCO2 +CCOCCNC(=O)Nc1ccc(-n2cncn2)c(C(F)(F)F)c1 +CNc1snc(C)c1C(=O)N1CCC(OCC(C)C)CC1 +CCC(C)(C)NC(=O)CSc1ccc(F)cc1 +O=C(Nc1cc(Cl)ccc1C(=O)N1CCCCC1)c1cccnc1 +CCN(CCCO)S(=O)(=O)c1c(C)noc1C +C=CCNS(=O)(=O)c1cc(Br)ccc1OC +c1ccc(COC2C(NCc3cccs3)CN3CCOCC23)nc1 +CCCn1c(SC(C)C(N)=O)nnc1-c1cccc(C)c1 +O=C(NCc1ccc(F)cc1)NC1CCN(C(=O)c2ccco2)CC1 +CCN(CCC#N)C(=O)CNc1ccc2c(c1)Cc1ccccc1-2 +Cn1cnc(CNC(=O)N2CCC(Oc3cccnc3)C2)n1 +O=C(CN1CCc2ccccc21)NCc1ccccc1Cn1cccn1 +C=CCN1C(=O)C(C)(C)COc2cc(NC(=O)CC)ccc21 +Cc1nnc2n1CCN(C(=O)Cc1ccc3c(c1)CCCC3)C2 +C=CCCCN(C)C(=O)c1ccc(C(=O)OC)cc1 +Cn1c(=O)c2c(ncn2CC(=O)OC2CCCCCC2)n(C)c1=O +Cc1ccc(O)c(NS(=O)(=O)N2CCCCC2)c1 +N#CC(C(=O)c1ccccc1Cl)c1nc(=O)c2ccccc2s1 +Cc1cccc2ncc(C(=O)N3CC4CCC(C3)N(C)C4=O)c(=O)n12 +CCC(C)NC(=O)C1(C)CCC(=O)N1Cc1cc(OC)ccc1OC +CC(C)C(NC(=O)c1cccnc1)C(=O)N1CCNCC1 +COc1c(C)cnc(CNC(=O)NC(C)C2CCCO2)c1C +COC(=O)CCC(=O)Nc1cccc(N(C)C(C)=O)c1 +Cc1noc(C)c1CC(=O)NCCc1c[nH]c2ccccc12 +Cc1nc(C(C)(C)NC(=O)NCCc2cccs2)sc1C +CC(=O)c1cc(C(=O)N(C)c2ccc(C)cc2C)n(C)c1 +COC(=O)c1ccc(-c2ccc3nc[nH]c(=O)c3c2)cc1 +CCc1nn(-c2c(F)cccc2F)c2c1C(=O)CCC2 +COc1ccc(C(O)Cn2nccc2-c2ccncc2)cc1F +Cc1cnc(C(=O)Nc2nc3c(s2)CCCCC3)cn1 +CCCC1CN(C(=O)Nc2nnc(CC(C)C)s2)CCO1 +Cn1ncc(N2CCC(NC(=O)c3cccnc3)CC2)c(Cl)c1=O +COc1ccc(S(=O)(=O)Nc2ccccc2)cc1Cl +Cc1nc2nc(N)nn2c(C)c1CC(=O)N(C)CCNC(=O)C(C)C +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)C(C)NC(N)=O +Cc1cccc(S(=O)(=O)Cc2ccc(OC(F)F)cc2)c1 +Cc1cc(C)n(-c2ccc(C(=O)NCCCn3ccnc3)cc2)n1 +CCn1cnnc1C1CCN(C(=O)C2CCOc3ccccc32)CC1 +NS(=O)(=O)CCCC(=O)NC1C(=O)Nc2ccc(F)cc21 +COc1ccnc(NC(=O)c2ccc(S(C)(=O)=O)cc2)c1 +COc1ccc(-n2ncc(C(C)=O)c2C)cc1Cl +COCC(=O)NCC#CCOc1cccc2c1OC(C)(C)C2 +CCc1nc2n(n1)C(CC(=O)Nc1cc(Cl)ccc1OC)C(=O)N2 +Cc1cc(NC(=O)c2cnc(OC(C)C)c(Cl)c2)n(CCC#N)n1 +CCn1c(C)cc(C(=O)NC(C)c2ccc(C)o2)c1C +COc1cc(NC(=O)CNc2cc(C)ccc2OC)cc(OC)c1 +CSc1ccc(NC(=O)NCc2cnc(C)s2)cc1 +CNC(=O)C1CCCN1S(=O)(=O)c1cccnc1 +O=C(NCCCc1cccc(F)c1)NCc1ccc2c(c1)OCO2 +Cc1ccc(F)cc1S(=O)(=O)NCCCCn1ccccc1=O +O=C(OCc1nnnn1-c1ccccc1)C1COc2ccccc21 +CC(Sc1ccccn1)C(=O)NCC(C)c1cccs1 +CCOC(=O)NCCC(=O)Nc1cc(Cl)ccc1SC +Cn1nc2c(cc1=O)CN(C(=O)CCCc1cc(F)ccc1F)CC2 +Cc1cc(C(=O)Nc2cccc(Oc3ccncc3)c2)c(C)o1 +CC(Oc1ccc(F)cc1F)C(=O)Nc1ccccc1N +Nc1nc2ccccc2n1CCCOc1ccccc1 +COc1cccc2c1OCC(NS(=O)(=O)c1cc(C)ccc1C)C2 +CCn1c(C2CC(=O)N(CC3CC3)C2)nc2ccccc21 +Cc1noc(CCC(=O)NC2(c3cccc(Cl)c3)CC2)n1 +COCCNC(=O)c1ccn(-c2ccc(OC)cc2)n1 +Cc1ccc(-c2noc(Cn3nc4ccccn4c3=O)n2)cc1 +COc1cccc(NC(=O)c2cc3c(cc2OC)OCCCO3)c1 +O=C(NCCNc1ccc2ccccc2n1)c1cnn[nH]1 +CCC(C)N(C)C(=O)NC(C)c1nc2ccccc2[nH]1 +CCCn1c(-c2nnc(CC)o2)cc2ccccc21 +CNC(=O)C1(C)CN(C(=O)c2cncs2)CCO1 +CCCCn1ncc(-c2ccc(OC)cc2)c(CC#N)c1=O +CC(=O)N(CCCNC(=O)Cc1cccs1)C(C)C +C=CCN1CC2(CCN(C(=O)c3ccccn3)CC2)OCC1=O +CCOC(=O)C=C(C)Nc1c(C)n(C)n(-c2ccccc2)c1=O +COc1ccc(CNC(=O)c2ccc(C)c(F)c2)cc1 +O=C(C1CCCO1)N1CCN(CCCc2ccc(Cl)cc2)CC1 +O=C(NCc1cccc(F)c1)c1ccc(Br)cc1 +O=C(c1cc[nH]n1)N1CCC2(CC1)Nc1ccccc1-n1cccc12 +COC(=O)Cn1cc(CNC(=O)NC2(C)Cc3ccccc3C2)nn1 +CS(=O)(=O)c1ccc(F)c(NCc2cccc(C#N)c2)c1 +CCOC(C)c1nccn1Cc1cc(Cl)ccc1OC +CC(NC(=O)Cc1ccccc1F)c1nc2cccnc2n1C(C)C +O=C(COc1ccc(Cl)cc1)NCc1cccc(O)c1 +COc1ccc(CC(=O)N2CCCCC2c2cc[nH]n2)cc1 +COc1ncc(C)cc1NC(=O)NCc1ncn(C)n1 +COc1ccc(-c2ccc(C#N)c(=O)n2CC(N)=O)cc1OC +Cc1ccc(NC(=O)c2ccc(Cl)cc2N)cc1F +O=C(CCn1nnc2ccccc2c1=O)N1CCC2(CC1)OCCO2 +Cc1nc(C)c(CC(=O)Nc2cccc(Br)c2)c(=O)[nH]1 +Cc1nc(CSc2nc(-c3ccccc3)ns2)no1 +Cc1oc(COc2ccc(Cl)cc2)nc1CCO +COCCCNC(=O)N1CCN(Cc2ccc3c(c2)OCCO3)CC1 +COC(=O)Cn1ccnc1-c1cncc(Br)c1 +O=S(=O)(NCc1ccccc1)Nc1ccc(F)nc1 +O=C(COc1ncnc2ccccc12)c1ccc2c(c1)OCCO2 +O=C(OCc1cnn(-c2ccccc2)n1)c1cc(=O)[nH]c2ccccc12 +CCS(=O)(=O)N1CCC2C1CCC(=O)N2Cc1csc(C)n1 +O=C(NCCc1ccccc1)Nc1c[nH]c(=O)[nH]c1=O +CCOC(=O)N(C)c1ccc(NCc2ccc(C(=O)NC)cc2)cc1 +COc1cccc(CNC(=O)c2nc3c(OC)cccc3c(=O)[nH]2)c1 +Cc1ccc(-c2[nH]ncc2C(=O)NCc2ccccn2)cc1 +CCCNC(=O)NCc1cn(-c2ccc(OC)cc2)nn1 +Cc1cc(NC(=O)NC2(C(F)(F)F)CCCCC2)n(C)n1 +Cn1cnc2cc(C(=O)NC(C#N)c3cccc(Cl)c3)ccc21 +CCOC(=O)c1nnn(CC(=O)NC(C)c2ccccc2)c1N +c1ccc(C(c2ccccc2)c2nn3cnnc3s2)cc1 +Cc1cc(NC(=O)Cn2nnc(-c3ccccc3)n2)c2ncccc2c1 +CC(C)n1cc(NC(=O)c2cccnc2N(C)C)cn1 +CCc1cccc(NC(=O)NCCC(=O)OC(C)C)c1 +CN(CCNC(=O)c1csc(-c2cccs2)n1)S(C)(=O)=O +CCOC(=O)CN(C(=O)c1c[nH]c(=O)cn1)C(C)C +Cc1cccn2cc(CC(=O)NCCC(=O)N3CCCCCC3)nc12 +COC(=O)C1CN(Cc2ccccc2OC)CCC1=O +CC(C)n1ncc2c(C(=O)NCc3cccnc3)cc(C3CC3)nc21 +CCn1c2ccccc2c(=O)c2cc(Cl)ccc21 +CCN1C(=O)CCc2cc(NC(=O)c3cc4ccccc4o3)ccc21 +Cc1cc(O)ccc1NC(=O)c1ccc(F)cc1Cl +COC(C)(CNS(=O)(=O)c1ccccc1)c1ccccc1F +CN(Cc1cc(Br)ccc1F)C(=O)CCn1cncn1 +CC(C)(C)OC(=O)N1CCN(C(=O)NCCc2ccccc2)CC1 +CC(=O)Nc1sc(C(=O)OC(C)C)c(C)c1C(N)=O +Cc1ccc(=O)n(CCC(=O)Nc2ccc(C#N)cc2)c1 +Cc1ccc(CC(=O)N2CC=C(c3c[nH]c4ccccc34)CC2)cn1 +CCC(C)c1ccc(C(O)CNCc2ccccn2)cc1 +Cc1ccc(-c2ccc(=O)n(CC(=O)NCc3ccccc3)n2)c(C)c1 +COc1cccc(C(=O)NCCC2=CCOCC2)c1F +CC1CCN(C(=O)NCc2ccc(-n3ccnc3)cc2)C(C)C1 +CC(C)n1c2ccccc2c2nnc(SCC(N)=O)nc21 +CN(CCN(C)C(=O)c1ccc2nncn2c1)C(=O)OC(C)(C)C +O=C(NCc1ccc(-n2cccn2)cc1)c1ccnc(-n2cncn2)c1 +O=C(Nc1cc(F)ccc1F)N1CCc2ccccc2C1 +CC(=O)NCC1CCCN(C(=O)c2c(C)[nH]c3ccccc23)C1 +Cc1ccc(-c2noc(CCC(=O)N3CCOCC3)n2)cc1 +COc1c(C(=O)OCC2(O)CCCC2)c(C)nn1C +CCCNC(=O)c1ccc(-c2ccccn2)nc1N +CCOC(=O)Cn1c(=O)c2c(nc3oc(C)cn32)n(C)c1=O +CCC(C)N(C)C(=O)Nc1cccnc1-n1cncn1 +CC(c1ccc(Cl)cc1)N(C)C(=O)CCNC(=O)OC(C)(C)C +CCOc1ncccc1C(=O)NCCc1nc(C(C)C)no1 +CCOC1CCCN(C(=O)NCc2cccc(C(=O)NC(C)C)c2)C1 +CCn1c(C)cc(C(=O)NCc2ccc(N3CCCC3=O)cc2)c1C +CCOc1ccc(C(=O)C(C)CC(=O)OC)cc1 +COC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2ccco2)c1C +Cc1cnc(NCCCn2nc(C)c(C)c2C)nc1 +CCN1CCOCC1C(=O)Nc1ncc(Cc2cccc(F)c2)s1 +CC(C)CC(C#N)CC(=O)Nc1ccc2c(c1)OCO2 +CC(C)Oc1ccc(Cc2nn(CCO)c(=O)[nH]c2=O)cc1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)Nc1ccc(C)cc1 +Cc1cc(C)n(-c2ccnc(N3CCCCC3)n2)n1 +O=C(Cc1n[nH]c(=O)c2ccccc12)N1CCCC1C1CCCC1 +CC(NC(=O)c1ccc(N(C)C)c(F)c1)c1cccs1 +CNC(=O)C(NC(=O)Cc1ccc2ccccc2c1)C(C)C +Cc1cc(C(F)(F)F)nc(CCNC(=O)c2ccsc2)n1 +O=C(CCCn1nc(-c2ccccc2)ccc1=O)NCC1CCCO1 +CCc1c(C(=O)N2CCOC(C)C2)cnn1-c1ccccc1 +O=C1Cc2[nH]c3cccc(Br)c3c2C1 +C=CCn1c(SC)nnc1-c1ccc2ncccc2c1 +Cc1nnnn1-c1cccc(NC(=O)NCCCO)c1 +CCc1c(C(=O)NCc2ncn(C)n2)cnn1-c1ccc(C)cc1 +CCOC(=O)Cc1csc(NC(=O)Cn2ccccc2=O)n1 +CCc1ccc(CCNC(=O)C(N)Cc2ccccc2)cc1 +C=CCCCN(C)C(=O)c1cc(Cl)c(OC)c(OC)c1 +CCN(CCC(F)(F)F)C(=O)c1cccc(Cl)c1 +O=C(c1cccc(Br)c1)N1CCC(O)(C(F)(F)F)C1 +CC1CCN(C(=O)c2c[nH]c3ccc(Cl)cc3c2=O)CC1 +Cc1cccc(C(=O)NCc2c(C)nc3sc(C)nn23)c1 +COC(=O)CN(Cc1ccncc1Cl)CC(C)C +CC(NC(N)=O)C(=O)NCc1ccc(-c2nc3ccccc3s2)o1 +CN(C(=O)COc1ccc(F)cc1)c1ccc(F)c(F)c1 +COc1ccc(NC(=O)CCc2ccccc2)cc1 +CC(C)CC(NC(=O)c1cccs1)c1nc2cccnc2n1C +Cc1cc(C(=O)Nc2cccc(N(C)C(=O)c3cc(C)no3)c2)on1 +CN(Cc1cccs1)C(=O)CN(C)c1ncnc2[nH]cnc12 +CCSc1nc(-c2cccnc2)cc(-c2ccco2)c1C#N +CC(=O)N1CCN(CC(=O)c2ccc(N)cc2)CC1 +COCCCNC(=O)Cc1cc(-c2ccc(F)cc2)on1 +CCOc1ccc2cc(C(=O)N3CCc4ccc(O)cc4C3)[nH]c2c1 +COc1cc(N)cn2cc(-c3cc(F)ccc3F)nc12 +CC(=O)c1c(C)[nH]c(C(=O)N(C)Cc2cccs2)c1C +COCCN(CCOC)C(=O)NC1CCC(O)CC1 +COc1ccc(CC(=O)Nc2cc(C(C)=O)ccc2C)cc1 +Cc1cc(C(F)(F)F)c2c(n1)sc1c(N)ncnc12 +Cc1ccc(-c2cc(C(=O)N3CCCC3)c(C)[nH]2)cc1C +CC(C)CCC(=O)Nc1cnn(CC(=O)NC2CCCC2)c1 +COc1ccccc1CNC(=O)Nc1cccc(C)c1 +CCOc1ccc(C(=O)NC(C)(C)C)cc1Br +COc1ccc(-c2cc(C(=O)OC(C)C)n(CCO)n2)c(C)c1 +CN(CC1COc2ccccc2O1)C(=O)c1n[nH]c2ccccc12 +O=C(COc1ccc2c(c1)OCO2)NCCCN1CCOCC1 +Fc1ccc2c(c1)C=C(c1nc(-c3ccncc3)no1)CO2 +CCOc1ccccc1CNC(=O)Nc1ccnn1C(C)C +N#Cc1ccc(S(=O)(=O)Oc2ccccc2)cc1 +c1cncc(CNc2cc(-c3cncnc3)c3cc[nH]c3n2)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)CCNC(=O)C(C)(C)C +COc1ccc(F)cc1S(=O)(=O)N(C)CC(N)=O +Cc1cc(C)c(-c2cn(Cc3ccccn3)nn2)c(-n2cccn2)c1 +COc1ccc(NC(=O)NCC2(O)CCCCCC2)cc1 +COCC(O)CN(C)C(=O)c1ccc(Br)cc1O +Cn1cc(C(=O)N2CCN(CC3CCCC3)C(=O)C2)c(C(C)(C)C)n1 +Cc1ccccc1Nc1nc(N)nc(COC(=O)C2CCCO2)n1 +CC1COCCN1CC(=O)N(C)C(C)c1cc2ccccc2o1 +CC(CC#N)N(C)C(=O)c1cccc(COc2cccc(F)c2)c1 +CCCN(CCC)C(=O)c1onc(S(=O)(=O)CC)c1N +CN(CC1CCCO1)C(=O)Cc1ccc(N2CCCC2=O)cc1 +O=C1CCc2ccccc2N1CCC(=O)N1CCc2ccccc21 +CC=Cc1ccc(OCC(=O)Nc2ccccc2C(C)=O)c(OC)c1 +COc1ccccc1CNC(=O)c1cnc2ccc(C)cn12 +O=C(Cc1cc(-c2cccs2)on1)NCCCN1CCOCC1 +CCn1c(=O)c2sccc2n(Cc2cccc(C)c2)c1=O +CC(C)c1csc(=NS(=O)(=O)c2cc(N)cs2)[nH]1 +Cc1nnc(Nc2ccc3c(c2)OCCCO3)c(C#N)c1C +CCS(=O)(=O)c1ccc(NC(=O)c2ccoc2C)cc1 +COCC(O)c1cc(F)c2c(c1)C(NC(C)=O)CCO2 +CC=CCOC(=O)C1=C(C)NC(=O)NC1c1ccc(O)c(OCC)c1 +O=C(Cn1cnc2c(cnn2CCO)c1=O)Nc1ccc(F)cc1F +COc1cccc(COc2ccc3cc(C(C)=O)c(=O)oc3c2)c1 +CC1CCC(C(N)=O)CN1C(=O)C1CC(=O)N(Cc2ccco2)C1 +CN1CCc2nc3cc(Cl)cc(Cl)c3c(C#N)c2C1 +Cc1cn(-c2ccccc2Cl)nc1NCc1cccc(C(N)=O)c1 +Cc1nc(CNC(=O)C2(c3ccc(F)cc3F)CCCC2)no1 +CC1(C)CCCN1C(=O)c1ccc(N2CCCS2(=O)=O)cc1 +CC(Oc1cccc(Cl)c1Cl)C(=O)NC(C)(C)C#N +CC(C)C(=O)NCCNC(=O)c1cn2cccnc2n1 +N#Cc1nc(C=Cc2ccc(F)cc2)oc1NCC1CCCO1 +Cc1ccc2c(c1)N(CC(=O)c1cc(C)n(C3CC3)c1C)C(=O)CO2 +O=S(=O)(c1ccccc1)C1(c2ccccc2)OCCO1 +CC(C)C(NCc1cccc2c1OCCCO2)C(=O)N(C)C +C=C(C)CN(CC)C(=O)CN1CCc2cc(F)ccc2C1 +Nc1ccc(C(=O)c2ccc3c(c2)OCCO3)cc1N +CCOCC(O)CNc1nncc(-c2ccc(C)o2)n1 +O=C(NCCO)Nc1cc(Br)ccc1N1CCOCC1 +Cc1ccc2ncc(C(=O)Nc3cccc(S(C)(=O)=O)c3C)n2c1 +CC(=O)Nc1ccc(NC(=O)c2cc(Br)cn2C)cc1 +CC(=O)c1ccccc1NC(=O)c1c(F)cccc1F +CCCCS(=O)(=O)NC(=O)Nc1ccccc1 +CC(C)NC(=O)CN(C)C(=O)C1(c2ccc(F)cc2)CCOCC1 +CCc1nn(C)cc1CN1CCN(C(=O)CN2CCOCC2)CC1 +CCOC(=O)N1CCC(NC(=O)c2cc3n(n2)CCCO3)CC1 +COc1ccc(C)cc1NC(=O)c1nc(C2CCC2)oc1C +Cc1cccc(OCCSc2nnc(-c3ccncc3)n2C)c1 +COc1ccc(Cl)cc1NC(=O)Nc1cccc(NC(C)=O)c1 +Cc1nc(N)c(C#N)c(CCCNC(=O)c2ccccc2)n1 +CN1C(=O)CCC(C(=O)NCC(=O)C(C)(C)C)C1c1ccc(F)cc1 +CC1(C)C(NC(=O)CCCc2ccc3[nH]c(=O)[nH]c3c2)C2CCOC21 +COCC(=O)Nc1nnc(-c2ccc(OC)cc2)s1 +CCC(C)C(NC(=O)c1ccc(N(C)C)nc1)C(N)=O +C=C(C)CN(CC)C(=O)c1cc(N)c(F)cc1Br +CCN(Cc1ccncc1)Cc1nc(-c2cccc(Cl)c2)no1 +COc1c(C(=O)N2CCCC(n3cncn3)C2)c(C)nn1C +Cc1ncc(C(C)NCc2ccccc2F)s1 +O=C(c1cccc(Br)c1)N1CCC2(CC1)OCCCO2 +Cc1ccccc1CC(=O)N1CCN(S(=O)(=O)N(C)C)CC1 +CC(C)c1noc(C(C)Sc2nnnn2-c2ccccc2)n1 +COc1ccc(CC(C#N)c2ccccc2F)cc1OC +Cc1c(Br)c(C)c2oc(=O)n(C)c2c1C +O=C(NCCOc1ccccc1)NCC(O)c1cccs1 +Cc1nn(C)c2ncc(NC(=O)N(C)Cc3cc(Cl)cn3C)cc12 +CCOC(=O)Cn1cnc2c(-c3ccc(Cl)cc3)csc2c1=O +CC(C)N(CCC#N)C(=O)CCCc1ccccc1 +CCn1cc(CN(C)C(=O)Nc2ccccc2)cn1 +CC(=O)c1ccc(NC(=O)Nc2c[nH]c3ccccc23)cc1 +COCc1nc(N(C)CCN2CCCCC2=O)c2cnn(C)c2n1 +O=C(NCCc1ccc(O)cc1)c1cc2ccccc2[nH]1 +CCc1c(C)nc(-n2nc(-c3cccs3)cc2NC(C)=O)[nH]c1=O +O=C(Oc1ccc2ccc(=O)oc2c1)c1cc(Cl)ccn1 +Cc1cc(C(=O)Nc2c(C)nn(C)c2C)nc(N2CCCCC2)n1 +COCCC(C)NC(=O)N(C)Cc1nc2c(s1)CCCC2 +Cc1c(F)c(F)c(C(=O)N2CCOCC2)c(C)c1Cl +O=S(=O)(Cc1nnnn1-c1ccccc1)c1ccc(F)cc1 +O=C(CSc1ccc(F)cc1)N1CCC(Oc2ccccc2)CC1 +CN1CC(C(=O)NCCCN(C)c2ccccc2)CC1=O +COCC(C)(O)CNC(=O)c1ccccc1SC +O=c1c(SCc2ccccc2)nccn1-c1ccccc1 +Cc1csc(SC(C)C(=O)N2CCc3ccccc3C2)n1 +Cc1ccccc1CCNC(=O)C(C)Sc1nc(C)c(C)o1 +CCOC(=O)c1cnn(C2CCCN(C(=O)c3cccnc3)C2)c1 +CCc1nc(C)c(C(C)N(C)C(=O)NCCOC)s1 +CC(=O)c1ccc(S(=O)(=O)N(Cc2ccccc2F)C2CC2)cc1 +O=C(CN1CCCOCC1)c1ccccc1Br +CC1CCC(CCC(=O)NC(Cn2cccn2)c2ccccc2)O1 +Cc1nc(NC(=O)c2ccc(C#N)cc2F)ccc1Br +CCNC(=O)c1nc(C(=O)NCc2ccc(F)c(Cl)c2)cs1 +COc1cc(C)c(CNc2ccc3oc(C)nc3c2)cc1OC +CC(C)CNC(=O)c1cc(=O)c(OCc2ccc(Cl)cc2)co1 +CC(C(=O)Nc1c[nH]cc(Br)c1=O)c1cccc(F)c1 +CC(C(=O)NC1CCSc2ccccc21)n1ccnc1 +CCCc1cc(C(=O)Nc2ccc(OC)c(OC)c2)cs1 +Nc1nc(COCC2CCCCC2)nc2sccc12 +Cc1cc2occ(CC(=O)N3CCN(CCO)CC3)c2cc1Cl +CC(C)C(C)CC(=O)Nc1ccc2c(c1)oc(=O)n2C +CC(C)c1nnnn1CC(=O)Nc1ccc(S(C)(=O)=O)cc1 +N#Cc1ccc(C2NCCc3ccc4c(c32)CCO4)cc1 +COc1ccc(C(=O)NCC(c2ccc(C)o2)N2CCOCC2)cc1 +CC(C)CNC(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1 +Cc1c(C(C)OC(=O)c2ccc(F)cc2)sc2ncnn12 +Cc1ccc(CNC(=O)CCn2ccc3ccccc32)cc1 +Cc1ccc(OCC(=O)Nc2ccc3c(c2)COC3)cc1 +COCCNC(=O)COc1cc(-n2cccn2)nc(C)n1 +N#Cc1ccc(C(c2nnnn2C2CCCC2)N2CCOCC2)cc1 +CC(NC(=O)c1cc(Cl)ccn1)c1ccco1 +N#Cc1cccc(C(=O)OC(C(N)=O)c2ccc(F)cc2)c1 +COC(=O)Cn1ncn2c(cc3sccc32)c1=O +COCCn1nc(C)c(CNC(=O)c2cccnc2OC)c1C +Cc1ccc(-c2nc(N3CCC(O)CC3)ncc2-c2cnccn2)o1 +CN(C)C(=O)N1CCC(C(=O)N(C)CCOCC2CC2)CC1 +CC1(C)Oc2cc(S(=O)(=O)NCC3CC3)ccc2NC1=O +O=S(=O)(NCc1nnc2n1CCCCC2)c1ccc2c(c1)CCO2 +COc1cc(CC(=O)NCCCO)c(OC)cc1C +COCCSc1cc(N2CCCCC2)ncn1 +CC(=O)c1ccccc1NC(=O)COC(=O)c1cccc(F)c1 +CCC(C)C(NC(=O)c1ccccc1)C(=O)N1CC(CO)OCC1C +COCn1cc(CO)c2cccc(Br)c21 +N#Cc1nsc(C(=O)Nc2ccc3ccccc3c2)c1N +CC(C)S(=O)(=O)NCc1ccc(C(F)(F)F)cc1 +O=C1CCCC2(CCN(C(=O)OCc3ccccc3)CC2)N1 +COC(c1ccccc1)c1nc(-c2ccc(CO)cc2)no1 +Cc1cc(N)ccc1NC(=O)c1cc2c(s1)CCCC2 +Cc1csc(CNc2cnn(-c3ccccc3F)c2)n1 +CC1CCN(C(=O)NCc2ccc(-n3cccn3)cc2)CC1 +C=CCc1ccccc1OCC#CCNC(=O)c1cc(C)on1 +Cc1ccccc1C(=O)NCC#Cc1ccc(N2CCOC2=O)cc1 +COc1cccc(CNC(=O)c2cn(-c3cccc(Cl)c3)nn2)c1 +COc1ccc(OC)c(NCC(=O)NCC2CC2)c1 +Cc1cc(C)c(C(=O)NC(C)c2ccc3c(c2)OCO3)c(=O)[nH]1 +Cn1cccc1CNc1cnn(Cc2ccccc2)c1 +CCCS(=O)(=O)NCc1cccc(Cn2cccn2)c1 +CCCNC(=O)Nc1ccc(-n2ccc(C(=O)OCC)n2)cc1 +CN(CCc1ccccn1)C(=O)NCCCn1cccn1 +COC(=O)N1CCN(c2ncnc3nc(C)cc(C)c23)CC1 +Cc1csc(CNC(=O)NCc2cnn(C)c2)n1 +C=CCN1C(=O)COC2CN(Cc3ccc(F)cc3)CC21 +COCC(=O)NCc1ccc(S(N)(=O)=O)cc1 +O=C(Cc1ccccc1Cl)N1CCCC(O)(CO)CC1 +O=C(NCC1CN(Cc2ccccc2)CCO1)NC(C1CC1)C1CC1 +CCN(CC)S(=O)(=O)CCNC(=O)c1ccc2c(c1)OCO2 +CCCNC(=O)NCCSc1ccc(C)cc1 +Cc1occc1C(=O)N1CCc2cc(F)ccc2C1 +CNc1snc(C)c1C(=O)N1CCc2ccc(Cl)cc21 +O=C(NCc1csc(=O)[nH]1)c1cc(F)ccc1O +O=C(NC1CC1)c1ccc(S(=O)(=O)c2ccc(Cl)cc2)nc1 +Cc1csc(SCC2CCN(C(=O)c3ccsc3)CC2)n1 +Cc1ccc(NC(N)=O)c(OCc2ccccc2)c1 +O=C(c1cc(=O)[nH]c2ccccc12)N(CC(F)(F)F)c1ccccn1 +CCOC(=O)c1c(C)[nH]c(C(=O)NCCc2ccccn2)c1C +C=CCCC(=O)OCc1nnc(-c2cccc(C)c2)o1 +O=C(CCC(F)(F)F)N1CCCC2CCCCC21 +CCOC(CC)C(=O)Nc1ccc(C#N)c(Cl)c1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)Nc2ccccc2F)c1 +O=C(CCc1ccccc1Cl)OCCN1CCCC1=O +CC(=O)N1CCc2ccc(NC(=O)Cc3ccc(Cl)cc3)cc2C1 +Cc1cnn(C2CN(c3nc(C(F)(F)F)nc4ccccc34)C2)c1 +O=C1C2CN(c3ncccn3)CC2CN1c1ccccc1 +CN(Cc1ccco1)C(=O)C1CCC(=O)N(C)C1c1cccc(F)c1 +COCc1nc(C)c(C(=O)Nc2ccccc2-n2ccnn2)s1 +O=C(NCc1nnnn1-c1ccc(F)c(F)c1)c1cccc(F)c1 +COc1ccc(CNC(=O)c2cnc(C3CCCO3)s2)cc1C +CC1CCC2C(C1)c1c(n(C)c(=O)n(C)c1=O)OC2(C)C +Cn1nccc1C(=O)N1CCC(C#N)(c2ccccc2)CC1 +Nn1c(SCC(=O)N2CCOCC2)nnc1-c1ccc(F)cc1 +Cc1ccc(NCCNS(=O)(=O)c2cccs2)nn1 +COCCNS(=O)(=O)c1cc2[nH]c3c(c2cc1C)C(=O)CCC3 +Cc1sc2ccccc2c1S(=O)(=O)N(C)C(C)CC#N +CC(Sc1nncn1C)C(=O)NCC1CCCO1 +COC(=O)c1ccc(N2CCOCC2)c(NC(=O)C(C)(C)C)c1 +CCc1nccn1-c1cccc(C2CCCN2c2ccnc(C)n2)n1 +Cc1nc(NC(=O)c2nc3ncccn3n2)sc1C +CC(C)CN(CC(F)(F)F)C(=O)c1cc(Cl)ccn1 +CCOc1ccc2c(c1OCC)C(c1ccoc1)NCC2 +Cc1cc(C(=O)NCC(F)F)c2c(-c3ccccc3F)noc2n1 +CN(Cc1ccc(OC(F)(F)F)cc1)C(=O)c1ccco1 +Cc1nc2cc(NC(=O)c3csc(C)n3)ccc2[nH]1 +Cc1ccc(C)c(CC(=O)NCC(=O)Nc2cccc3cccnc23)c1 +O=C(c1cc(Cl)cc(Cl)c1)N1CCOCC1c1ncon1 +CC(Nc1ccc(NC(=O)C2CC2)cc1)C(=O)NCc1cccs1 +Cc1cccc(C(=O)NCc2noc(CCc3ccccc3)n2)c1 +COCCCNC(=O)c1ccc2nc(N3CCOCC3)sc2c1 +O=C(Cc1ccsc1)NCC1Cn2nnc(-c3ccoc3)c2CO1 +Cc1ccc(C(=O)CCC(=O)Oc2ccc3c(c2)OCO3)cc1 +CCCCCSc1nc2[nH]c(=O)[nH]c(=O)c2[nH]1 +CNc1nnc(-c2sc(COC)nc2C2CC2)s1 +CN(Cc1nc(-c2cccnc2)no1)C(=O)c1ccc2ccccc2c1 +COc1cccc(C(=O)Nc2ccc(NCC(C)O)nc2)c1 +Nc1ccc2nc(NC(=O)CCC3CCCC3)sc2c1 +Fc1cc(F)c(F)c(SCCc2ccccn2)c1F +O=C(NCc1ncc[nH]1)Nc1cccc(COc2cccc(F)c2)c1 +CCC(C)NC(=O)CCc1csc(NC(=O)c2ccc[nH]c2=O)n1 +O=C(CNC(=O)Nc1ccc(F)cc1F)NCCc1ccccc1 +CCN1C(=O)c2ccc(C(=O)Nc3nncs3)cc2S1(=O)=O +O=C(CCNC(=O)NCc1cccnc1)NC1CCCC1 +CC1CCN(c2ncnc3onc(-c4cc(F)cc(F)c4)c23)CC1 +O=C(c1[nH]nc2c1CCCC2)N1CCN(c2ccccc2F)CC1 +CC1CN(CC(=O)c2ccc3c(c2)CCCC3)CCO1 +CCOc1ccc(C(=O)Cn2cc(N)cn2)cc1Cl +COc1ccc(NCc2ccccc2OC(F)(F)F)cn1 +CCNS(=O)(=O)c1cnn(C(CC)CC)c1N +CSc1nc2sc3c(c2c2nnnn12)CCCC3 +COCCCNC(=O)c1cnc(-c2ccncc2)nc1N +COC(=O)C1(CNC(=O)c2cc(Cl)ccc2Cl)CCOCC1 +Cc1c(NC(C)C(C)C)cccc1C(=O)NCc1ncn(C)n1 +CC(C)(C)CN1CC(Nc2ncnc3sccc23)CC1=O +O=C(NC(c1nccs1)C1CC1)N1CCCCC1c1cn[nH]c1 +Cc1cccc(C(=O)N2CCc3cc(N)ccc32)c1 +Cc1ccc(OCC(=O)NCC(F)(F)F)c(C)c1 +Cc1cc(F)c(C(=O)NCC(Cc2cnn(C)c2)C(N)=O)cc1F +COc1ccc(C2CCCN2C(=O)COC2CCCCC2)cc1OC +CCN(Cc1ccccn1)C(=O)Cc1cccc(OCC#N)c1 +Cc1ccc(-c2cnc(CCC(=O)NCC3CCCO3)o2)cc1 +CCCNC(=O)CN1CCN(C(=O)Cc2cccc(OC)c2)CC1 +CC(=O)N1CC(=O)Nc2ccc(Cl)cc2C1c1ccccc1 +Cc1ccc(NS(=O)(=O)c2cccc(N)c2)cc1C +CC(CO)NC(=O)NCc1cn2cc(Cl)ccc2n1 +CSc1ccc(NC(=O)NCC(=O)Nc2c(C)cccc2C)cc1 +COC(C)C(=O)Nc1ccc(Oc2ccccc2)nc1 +Cc1noc(-c2ccccc2NC(=O)c2ccco2)n1 +Cn1cc(C(N)=O)cc1C(=O)Nc1nccs1 +CCc1c(C2CCN(C(=O)c3n[nH]c4ccccc34)CC2)noc1N +Cc1csc(C(NC(=O)N(C2CC2)C(C)c2ccco2)C2CC2)n1 +O=C(NCC1(c2ccc(F)cc2)CCOCC1)c1n[nH]c2c1CCC2 +O=C(Nc1cc(F)c(F)c(F)c1)c1cccc(OCC(F)F)n1 +Cc1noc(C)c1C(C)C(=O)N(C)C(C)c1nc2ccccc2s1 +Cn1nc(C(=O)NCC2CCC2)cc1OCc1ccccc1 +CCC(NC(=O)c1ccccc1)c1ccc(OC)c(OC)c1 +Cc1cccc(CN(c2ncnc3c2cnn3C)C2CC2)c1 +CCc1nc(NCc2ccc3c(c2)CC(C)O3)c2cnn(C)c2n1 +N#CCCN(C(=O)Cn1cnc2ccccc2c1=O)c1ccccc1 +COC(=O)c1cccc(NC(=O)c2cccc(S(C)(=O)=O)c2)c1C +N#Cc1ccc(OC2CCC(NC(=O)CC3C=CCC3)CC2)nc1 +CCCn1c(=O)c(C(=O)NCCOC)nn(-c2ccccc2)c1=O +Brc1cccc(-c2nnc(C3CC3)o2)c1 +Cc1csc(-c2cccc(NC(=O)N3CCCC3CO)c2)n1 +CC(=O)Nc1ccc(SCc2nc3ccccc3nc2C)cc1 +Cc1nnc(SCC(=O)NC(C)c2ccc(F)cc2F)o1 +O=S(=O)(NCCCO)c1c(Cl)cc(Cl)cc1Cl +CC(OCC1CCCCN1C(=O)OC(C)(C)C)c1ccccn1 +Cc1ccc(C(=O)Nc2ccc(NC(=O)c3cnoc3C)cc2)s1 +OCc1cc2ccccc2nc1NCCOc1cccnc1 +CNC(=O)c1cccc(S(=O)(=O)Nc2ccc(OC)cc2)c1 +Cc1cc(CSc2ncnc3c2cnn3C)no1 +O=C(CNC(=O)c1cccc(-c2ccoc2)c1)Nc1cccc(F)c1 +O=C(NCC(F)(F)F)C1CCOc2ccccc2C1 +COC(=O)c1cccn1C1CCN(C(=O)COCC2CC2)CC1 +NC(=O)c1csc(CN2CCN(CC(F)(F)C(F)F)CC2)c1 +CCCC(=O)N1CCC(C(=O)NC(C)(C)C(=O)OC)CC1 +CCn1cnnc1CNC(=O)COc1ccc(C)cc1 +COC(=O)c1ccc(Cl)c(NC(=O)CCC#N)c1 +COc1cc(C)ccc1OC(=O)C=C1CCC(C)C1 +CS(=O)(=O)c1cc(C(=O)NCc2ccc(F)cc2)ccc1Cl +Cc1ccc2c(c1)OCC(=O)N2Cc1ccccc1 +O=C1CCCCN1c1ccc(CNC(=O)C2(c3ccccc3)CC2)cc1 +Nc1c(NCCc2cccs2)ncnc1NCc1ccccc1 +CCCNC(=O)CNC(=O)c1ccnc(-n2cncn2)c1 +Cc1ccc(NC(=O)CN(C)Cc2scnc2C)nc1 +Cc1cc2c(SCC(=O)NCc3cccs3)ncnc2s1 +CC(=O)c1cccc(NC(=O)C2CC(=O)N(Cc3ccccc3)C2)c1 +Cc1sc(=O)n(CC(=O)N2CCN(Cc3ccncc3)CC2)c1C +Cc1sc2ncn(CC(=O)N3CCc4ccccc43)c(=O)c2c1C +COc1ccc(OC)c(CC(=O)Nc2c(C)cc(C)nc2C)c1 +CCc1ccc(S(=O)(=O)CC(N)c2cccs2)cc1 +Cn1cc(NC(=O)c2c[nH]nc2-c2cccc(Cl)c2)cn1 +COCCC1(CO)CCCN(C(=O)c2ccc3c(c2)NC(=O)CN3)C1 +Cc1cc(CN2CCN(C(=O)CSc3nncn3C)CC2)no1 +CCc1ccc(N(C(C)C(=O)NC)S(C)(=O)=O)cc1 +COC(=O)c1cccc2c1CCCN2C(=O)c1sc(C)nc1C +CCOC(=O)N1CCN(C(=O)C(C)(C)CC)CC1 +CCC(=O)c1ccc(OCC(=O)N=c2sccn2C)cc1 +CN(Cc1cc(-c2cccnc2)no1)C(=O)c1ccc2ccn(C)c2c1 +Cc1cc(C(=O)N2CCN(c3cccc(C)c3C)CC2)ccc1N +CC(C)(CO)n1c(C(F)(F)F)nc2ccc(F)cc21 +c1ccc(-n2nnnc2NC2CCN(c3ncccn3)CC2)cc1 +COc1ccc(NC(=O)CNc2ccc(F)cc2)c(OC)c1 +O=C(NCC1CCC1)C1CCCN1C1=NS(=O)(=O)c2ccccc21 +NC(=O)c1cccc(CNC(=O)C2Cc3ccccc3C(=O)O2)c1 +CCCNC(=O)c1cc(CC)n2nc(-c3cccs3)cc2n1 +COc1ccccc1CN(C)C(=O)CCNC(=O)c1ccccc1C +Cc1ccc2c(c1)NC(N1CCN(CC3=CC=CC4N=CC=C34)CC1)O2 +Nc1cc(Cl)c(Cl)cc1NC(=O)c1ccco1 +Cc1cc(C)n(C(=O)COc2c(C)cccc2C)n1 +Cc1nc2cc(NC(=O)c3cc(C(C)(C)C)n[nH]3)ccc2o1 +CC1CCC(C)N(C(=O)Nc2ccc(OCCC(N)=O)cc2)C1 +CCSc1ccc(Cl)cc1NCc1noc(C)n1 +Cn1cccc(NC(=O)c2ccc(Cl)c(S(C)(=O)=O)c2)c1=O +Cc1nccn1-c1ccc(NC(=O)c2ccc(=O)n(C)n2)cn1 +CCn1c(NC(=O)CCNC(=O)OC(C)(C)C)nc2ccccc21 +Cc1nc(C2CC3CN(C(=O)c4cccn4C)CCC3O2)no1 +O=C(c1cccs1)N1CCN(Cc2ccc(Cl)cc2)CC1 +CC1CC(C)CN(C(=O)CNC(=O)c2cccc(Cl)c2)C1 +CC(=O)NCC(=O)N1CC2OCC(=O)N(Cc3cccc(C)c3)C2C1 +Cc1occc1CN(C)C(=O)c1c[nH]c(=O)c(Cl)c1 +COc1ccc(NC(C)=O)cc1S(=O)(=O)N(C)C(C)C +CC(=O)c1nc2ccccc2n1Cc1nnc(-c2ccccc2)o1 +CCc1ccc(-c2n[nH]c(SCCCO)n2)cc1 +Cc1nc(C(=O)Oc2ccc(C(=O)N(C)C)cc2)cs1 +Cc1[nH]c(=O)ccc1C(=O)NCCSc1ccc(Cl)cc1 +O=C(Cc1n[nH]c(=O)[nH]1)NCc1cccnc1-n1ccnc1 +COc1ccc(CSc2nc(C)cc(=O)[nH]2)cc1 +Cn1cc(C(=O)N2CCN(CC(O)C(C)(C)C)CC2)cn1 +COc1ccc(Br)cc1C(C#N)N1CCCCC1 +O=S(=O)(NCCc1ccc(O)cc1)c1cccc(F)c1 +N#CCCNC(=O)CNc1ccc(Cl)c(F)c1 +O=C(CCn1cnc2sccc2c1=O)Oc1cccc(F)c1 +CNC(=O)c1cc(OC)ccc1NC(=O)Cc1cccs1 +CCOCC(O)CN1CCN(C(=O)Cc2ccccc2C)CC1 +COc1ccc(C)cc1-n1nnc(C#N)c1-c1cccs1 +O=C(c1cccc(S(=O)(=O)NCC2CC2)c1)N1CCCC(O)C1 +COC(=O)c1cccc(OCc2cn3c(C)cccc3n2)c1 +Cc1ccc2nc(NC(=O)Cn3ccc(C(F)(F)F)n3)sc2c1 +C#CCOC(=O)CSc1nncn1-c1ccc(C(C)C)cc1 +CCNC(=O)NC1CCC(OC(=O)CN2CCCCCC2=O)CC1 +CCCOCC(=O)N1CCC(C(=O)OC)c2ccccc21 +CCCCC(=O)NCCN1c2ccccc2CC1C +Cc1c(C(=O)NC(C)(C)C)nnn1-c1ccc(F)cc1 +COc1cccc(C2CCCN2c2nc(C3CC3)no2)c1 +COc1cc(C(=O)N(C)c2ccc(F)cc2)sc1S(N)(=O)=O +CC1CC(C)CN(C(=O)CCCN2C(=O)CSc3ncccc32)C1 +CC(NC(=O)NCC1CCCO1)(C(F)(F)F)C(F)(F)F +c1ccc2c(c1)SCCCN2Cc1noc(C2CC2)n1 +CC(NC(=O)c1nnc2n(C)ccn12)c1ccccc1 +Cc1ccc(F)c(NC(=O)CN2C(=O)COc3ccc(C)cc32)c1 +COCCNS(=O)(=O)c1cccc2nonc12 +COc1ccc(OC)c(NC(=O)Cc2nonc2N)c1 +CCOc1ccccc1NC(=O)c1ccc(N)c(C)c1 +COc1ccc(C)cc1-n1ccc(C(=O)NCc2cscn2)n1 +C=CCN1C(=O)CCCC12CCCN(C(=O)Nc1ccccc1C)C2 +COc1ccc(NC(=O)Nc2c[nH]c3ccccc23)c(OC)c1 +Cc1ccc2c(NC(=O)c3ccc(C#N)cc3F)cccc2n1 +COc1ccc(Br)cc1C(=O)CN1CCOCC1 +CC1CCCC(CNC(=O)CNC2=NS(=O)(=O)c3ccccc32)C1 +COCCN(CC(C)C)S(=O)(=O)c1cc(C)ccc1C +Cc1ccnn1C(C)C(=O)Nc1ccccc1OC(F)F +Cc1nc2cc(C(=O)Nc3ccc(-c4nnco4)cc3)ccc2n1C +O=C(Nc1cc(C(F)(F)F)ccc1O)c1ccc[nH]1 +COC(=O)c1scc(-c2ccc(F)cc2)c1N +Cc1sc2[nH]c(SCCO)nc(=O)c2c1C +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)OCC#Cc1ccccc1 +O=C(COc1cccc(NCc2nnc(C3CC3)o2)c1)N1CCCC1 +COc1ccc(C(C)NC(=O)C(C)c2ccsc2)cc1OC +COC(=O)CN(C(=O)c1sc(-c2cccs2)nc1C)C(C)C +CSc1ccc(C(=O)NCC(O)c2ccc(Cl)cc2)cn1 +Cc1ccc(Cl)c(OC(=O)C2CCN(c3cnccn3)CC2)c1 +O=C(c1cc(C2CC2)on1)N1CCN(Cc2ccccn2)CC1 +O=C(NCc1cscn1)c1cnc2sccn2c1=O +Cn1ccc(NC(=O)c2cc(F)c(F)cc2Cl)n1 +Cc1cccc(NC(=O)c2nnn(-c3ccccc3)c2N)c1C +CCOC(=O)Cc1ccc(Br)cc1F +O=C(c1cc[nH]n1)N1CCC(c2nc(C3CCCC3)no2)C1 +O=c1[nH]nc(Cn2nnc(-c3ccc(Br)cc3)n2)[nH]1 +O=C(CN1C(=O)CCCc2ccccc21)NCCNc1ncccn1 +O=C(c1ccc(CNc2cnc3ccccc3n2)cc1)N1CCCC1 +Cc1cc(F)ccc1S(=O)(=O)NCC(=O)N1CCc2ccccc21 +CCN(CC(=O)NC)S(=O)(=O)c1cccc(F)c1F +O=C(Cc1cccc(C(F)(F)F)c1)NCCC(=O)N1CCCC1 +O=C(COC(=O)c1cccc(F)c1)NCc1ccc2c(c1)OCO2 +CNc1ncnc(Nc2nc3ccc(OC)cc3s2)c1N +COc1cccc(CC(=O)N2CCCC(C(N)=O)C2)c1 +Cc1cc(C(=O)N2CCCC2c2cnn(C)c2)c2ccccc2n1 +COc1cccc(OCc2nc(C(=O)NCC3CCCO3)cs2)c1 +Cc1ccc(SC2CCN(C(=O)OC(C)(C)C)C2)nn1 +CCC(NC(=O)CCCN1CCOC1=O)c1cc(F)ccc1F +CCn1c(SC(C)C#N)nnc1-c1cccs1 +CCSc1cc(C(=O)NCCc2ccccc2)ccn1 +C=CCn1c(C)c(C)c(S(=O)(=O)c2ccccc2)c1NC(C)=O +O=C(c1sccc1Br)N(CCO)C1CC1 +Cc1c(N)cccc1S(=O)(=O)N(C)C(C)CC#N +Cc1cc(=O)[nH]c(SCC2COC3(CCCCC3)O2)n1 +COc1cc(-c2c(C#N)c(N)n(N)c(=O)c2C#N)ccc1O +Cc1ccccc1CNC(=O)C(C)S(=O)(=O)c1ccc(O)cc1 +CC(=O)N1CCCn2nc(CNc3nc4ccccc4s3)cc2C1 +O=c1[nH]c(N2CCCCC2)nc2nccc(-c3cccnc3)c12 +COC(=O)c1ccccc1OS(=O)(=O)c1ccc(F)cc1 +O=C(NCC1COCc2nc3ccccc3n21)c1ccccn1 +O=C(CC1C=CCC1)NCC(O)c1ccccc1C(F)(F)F +COc1ccc2c(ccn2CC(=O)N2CCc3ccc(O)cc3C2)c1 +Cc1c(NC(=O)C2CCCN(S(C)(=O)=O)C2)cnn1C +O=C(Cn1cnc2sc3c(c2c1=O)CCCC3)N1CCCCC1 +CC(=O)NC(C)(C)c1noc(Cn2nc(C)c3ccccc3c2=O)n1 +O=C(NCCc1cn2ccccc2n1)NCCc1cccs1 +O=C(Nc1cn[nH]c1)c1ccc(OCC(F)F)nc1 +Cc1ccc(C)c(C(=O)CSc2nnc(C3CC3)n2C2CC2)c1 +C#CCN1CCN(C(=O)NC2CCN(C(=O)C3CCCC3)C2)CC1 +COc1ccc(NC(=O)COc2cccc(F)c2)c(OC)c1 +CCCn1nnnc1COC(=O)C12CC3CC(CC(Cl)(C3)C1)C2 +COCCNc1ncnc(Nc2cccc(C)c2C)c1N +Cc1cc(-c2cn[nH]c2C2CCCN(Cc3cscn3)C2)on1 +COCCCn1c(=O)[nH]c(=O)c2c3c(cnc21)C(=O)CC(C)(C)C3 +CC(C)(C)OC(=O)Nc1cccc(C(=O)OCC2CCOCO2)c1 +O=C(OCc1ccc2c(c1)OCO2)c1cn(Cc2ccccc2)nn1 +O=C(NCC1(CO)CC1)Nc1ccc(Cl)cc1 +Cc1cc2c(N)cc(Br)cc2c(=O)n1C +CCSc1nnc(C2Oc3ccccc3OC2C)n1CC +O=C(Nc1cccc(C(F)(F)F)c1)C1C2CC3OC(=O)C1C3C2 +CC(=O)Nc1ccc2cc3ccc(NC(C)=O)cc3nc2c1 +Cn1cnc(CNC(=O)NC2CCCN(Cc3ccccc3)C2=O)n1 +Cn1nc2c(c1NC(=O)COc1ccc(Cl)cc1Cl)CCC2 +CCOC(=O)Nc1cccc(NCc2cn3cccnc3n2)c1C +Cc1nc2cc(C(O)Cn3cc(N)cn3)ccc2n1C +CC1CCc2nc(NC(=O)c3ccc4c(c3)CCC(=O)N4)sc2C1 +CNC(=O)c1cc2c(s1)CCN(C(=O)C1CC(=O)N(C3CC3)C1)C2 +CCC(C)NC(=O)NCCNC(=O)c1ccoc1 +O=C(COc1ccccc1)Nc1c[nH]cc(Br)c1=O +O=C(NCc1ccc(-n2cnc3ccccc32)nc1)C1CCC1 +Cc1ccc(F)cc1S(=O)(=O)Oc1cccc(-n2cnnn2)c1 +CCc1c(C)sc2nc(NCCO)n3nc(-c4ccco4)nc3c12 +Clc1cccc(-c2nnc(SCCn3cccn3)o2)c1 +Cc1ccc(C)c(NC(=O)C(C)n2nnc(C#N)c2C)c1 +COc1ccc(Cl)cc1C(=O)NC1CCCNC1=O +CCCC1CN(C(=O)c2cc(S(N)(=O)=O)ccc2Cl)CCO1 +CC(=O)Nc1ccc(NCC(=O)Nc2ccccc2Cl)cc1 +O=C1COc2ccccc2CN1c1cc(F)c(F)cc1F +CC(C)(C)N1CC(C(=O)NCC2(c3ccc(Cl)cc3)CC2)CC1=O +Cc1ccccc1-n1cnnc1SC(C)C(=O)N1CCC(C)CC1 +OC(CNc1ncnc2sc3c(c12)CCCC3)c1ccccc1 +CCNC(=O)c1ccc(NC(=O)N2CCC3(CC2)OCCO3)cc1 +COCCn1cnnc1C1CN(Cc2cnn(C)c2)C1 +CCOc1ccc(C(=O)Nc2ccc(F)c(F)c2)nn1 +Cc1ccc(C(=O)NCCNC(=O)c2cccc(Cl)c2)cc1F +CC(NC(=O)c1ccc(-n2cncn2)nc1)c1ccc(F)c(Cl)c1 +COc1ccc(C(=O)c2c(N)nc3n2CCC3)cc1OC +CC(C)N1CC(C(=O)NCc2ccc(NC(N)=O)cc2)CC1=O +CN(C)C(=O)C(C)(C)NS(=O)(=O)c1ccc(F)cc1 +CC1CCOC1C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +CN(Cc1nccn1Cc1ccccc1)C(=O)Cc1cccc(O)c1 +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)CCCNC(=O)C1CC1 +Cc1nc(C2CCCCCN2C(=O)Nc2c(C)cccc2C)no1 +COCCCC(=O)Oc1cccc(C(=O)N(C)C)c1 +Cc1ccc(CNc2ccc(CNS(C)(=O)=O)cc2)s1 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)N1CCOCC1 +Cn1c2c(c(SCc3ccc(F)cc3)nc1=O)CCC2 +CC(=O)Nc1cccc(NC(C)c2ccc(O)cc2)c1 +CCCNC(C#N)CCOc1cc(F)ccc1F +CCC(C)OC(=O)c1cccc(NC(=O)c2ccco2)c1 +O=C1CC(c2nnc(Cc3ccc(F)cc3)o2)CN1c1ccccc1 +Cn1c(SCC(=O)Nc2ccccc2C#N)nnc1-c1ccccc1 +Cc1cccc(C2(C(=O)NCc3cccc(Cn4cncn4)c3)CC2)c1 +CCOc1ncccc1C(=O)Nc1ccccc1C(N)=O +COc1ccc(-c2nc(CSc3nnnn3C)cs2)cc1 +O=C(c1cccc2nccnc12)N1CCCC1c1nc2ccccc2[nH]1 +NC(=O)C1CN(CC(=O)Nc2ccc(F)c(Cl)c2)c2ccccc21 +CCNC(=O)c1ccc(C)c(NC(=O)N(C)Cc2ccncc2)c1 +N#Cc1ccccc1C(C(N)=O)(c1ccccc1)c1ccccc1C#N +Cc1nc(COc2cccc(N)c2)n2ccccc12 +CC(=O)NC(Cc1c[nH]c2ccccc12)C(=O)Nc1ccnc(C)c1 +COc1cccc(NC(=O)c2nc(C)cc3c(N)cccc23)c1 +Cc1ccc(Nc2nc(N)nc(CN3CCC(C(N)=O)CC3)n2)cc1 +Cn1c(-c2nnc(SCC(N)=O)o2)cc2ccccc21 +O=C(NCc1nc2ccccc2[nH]1)c1nnn(-c2ccccc2)n1 +O=S(CCNc1nccc(C(F)(F)F)n1)c1ccccc1F +Cc1ccc(C(=O)N2CC=C(c3ccc(F)cc3)CC2)c(=O)[nH]1 +CCCCCNC(=O)c1cc(S(N)(=O)=O)ccc1N +COC(=O)c1cc(NC(=O)C2Cc3ccccc3S2)c(F)cc1F +Cc1occc1C(=O)N1CC2CN(c3ncccn3)CC2C1 +COc1ccc2c(=O)cc(-c3ccccc3)oc2c1O +COc1cc(CC(C#N)C(=O)Nc2cc(C)cc(C)c2)ccc1O +Cc1noc(C)c1COc1ccccc1C(=O)Nc1nncs1 +COCCn1cnnc1SCc1cc(=O)oc2cc(OC)ccc12 +COc1cc(C)sc1C(=O)N1CCN(C(=O)N(C)C)CC1 +CSc1ccc(CNc2cccc(N3CCCNC3=O)c2)cc1 +CCOc1ncccc1NC1CCN(C(C)=O)CC1 +Cc1cc(S(=O)(=O)N(C)CC(=O)N(C)C)ccc1Br +CC(CNC(=O)C1CCCN(C(N)=O)C1)N(C)c1ccccc1 +Cc1cc(=O)[nH]c(SCC(=O)N2CCC(c3ccccc3F)C2)n1 +CCn1ccc(C(=O)N2CCC(CCOc3ccccc3F)CC2)n1 +COCC(=O)N(C)CC(=O)N1CCCc2c(F)ccc(F)c21 +Cc1cc(Br)ccc1NC(=O)CN(C)C(C)C#N +O=C(NCc1ccc(C(=O)N2CCOCC2)o1)NC1CCCC1 +Cc1noc(C)c1CS(=O)(=O)c1ccc2c(c1)OCCO2 +CC(=O)Nc1cccc(OCCNC(=O)NCc2csc(C)n2)c1 +COc1ccc(-c2ccc3c(=O)[nH]cnc3c2)c(F)c1 +CCc1c(C(=O)NCc2cnc(C)s2)cnn1-c1ccccn1 +CC(C)(CNC(=O)CC1C=CCC1)NS(C)(=O)=O +O=C(Nc1cccc(Cl)c1Cl)c1ccc(N2CCCC2=O)cc1 +CCn1c(C)nc2cc(NC(=O)c3c4c(nn3C)CCCC4)ccc21 +Cc1nc(C(NS(=O)(=O)N(C)C)c2ccccc2F)no1 +O=c1c2oc3ccccc3c2ncn1Cc1coc(-c2cccs2)n1 +COC(=O)c1ccc2c(c1)CCN2C(=O)COc1ccccc1OC +Brc1c(OCc2nnnn2C2CC2)ccc2ccccc12 +COCCCN(C)c1nc(C)c2ccc(OC)cc2n1 +Cc1ccoc1C(=O)N1CCCC1C(=O)OCc1ccccc1 +Cc1ccc(S(=O)(=O)NCC2CN(CC(C)C)CCO2)cc1C +COc1cccc2c(=O)n(CC(=O)Nc3ccc(Cl)cc3)ccc12 +CCOCCCNC(=O)c1cc(C)nc(N2CCCCCC2)n1 +CC(C)S(=O)c1ccc(C(=O)N2CCc3cc(F)ccc3C2)cc1 +O=C(CC1CCCO1)Nc1ccc(NCC2CCCO2)c(F)c1 +CN(C)C(=O)CN(C)C(=O)c1ccc(NC(=O)c2ccco2)s1 +C=CCCCN(C)C(=O)Cc1cn(C)c2ccccc12 +C=CCN1CC2(CCN(C(=O)Cc3ccccn3)CC2)OCC1=O +CC(c1cccs1)N1CCN(S(C)(=O)=O)CC1 +CCOC(=O)c1c(NC(=O)CC#N)sc2c1CCCC2 +CNC(=O)C1CCC(NC(=O)N2CCCC2c2cccc(F)c2)CC1 +CCC(NC(C)C(N)=O)c1ccc(OC)c(OC)c1 +Cc1ccc(C(=O)C(C#N)c2ccccc2F)s1 +CCc1ncc(C(=O)NC2CC(=O)Nc3ccccc32)cn1 +O=C(Cc1ccc(F)cc1F)OCC1CC(=O)N(c2ccccc2)C1 +O=C(Cn1cnnn1)NCc1cc(Cl)c2c(c1)OCCCO2 +CC1(c2ccccc2)CN(C(=O)c2ccc(-n3ccnn3)cc2)CCO1 +COCCN(Cc1ccccc1)C(=O)Cc1cn2ccsc2n1 +O=C(NCCCC(=O)N1CCc2ccccc2C1)c1cccs1 +CC(C)N1CC(C(=O)N2CCCCC2Cn2cccn2)CC1=O +CC(C(=O)N1CCOCC1)N1CCN(C(=O)Nc2ccccn2)CC1 +Cc1cc(C(=O)N2CCCCC2C)c2c(C)noc2n1 +Cn1cc(CNC(=O)CSc2nnnn2C2CC2)cn1 +CCOC(=O)Cc1cncc(Cl)c1C(F)(F)F +CCOC(=O)c1ccc(CN2CCOC3CCCCC32)o1 +Cc1ccc(C(=O)C2CCN(Cc3cnc(C4CC4)s3)CC2)cc1 +CC(C)CNc1nc(-c2csc(N(C)C)n2)cs1 +CCSc1ccc(C(C)NC(=O)NCCc2ccccn2)cc1 +COC(=O)Nc1ccc(CNC(=O)C2CC2c2ccccc2F)cc1 +c1ccc(N2CCC(CNc3ncnc4[nH]ncc34)C2)cc1 +CC(=O)c1ccc(C(=O)N(C)Cc2cccc(-n3cccn3)c2)s1 +O=C(c1cnccn1)N1CCC(S(=O)(=O)c2ccccc2)C1 +c1cncc(Oc2nccnc2C2CCN(c3cnccn3)CC2)c1 +CNC(=O)c1cc(Cl)ccc1NC(=O)c1cnc(C)cn1 +CC(Oc1ccccc1C(F)(F)F)C(=O)Nc1ccn(C)n1 +CCc1nnnn1CC(=O)NCc1ccc(C)s1 +COc1ccc(Cc2nc(C)c(N)c(C)n2)cc1Cl +COCC(NC(=O)Nc1ccc2c(c1)COC2)C1CC1 +CCNC(=O)c1cccc(NCC(=O)NC(C)(C)C)c1 +CCOc1ccccc1N1CC(C(=O)NC2CCC(C)CC2)CC1=O +CC(=O)Nc1cccc(CNC(=O)NCC2CCC2)c1 +CCc1ncc2c(n1)CN(C(=O)CCn1c(CC)nc3ccccc31)C2 +N#Cc1ccc(C(=O)NC(CN2CCCC2=O)c2ccccc2)cc1 +O=C(c1ccccc1C(F)(F)F)N1CCC(CO)C1 +CNC(=O)CCc1ccc(NC(=O)c2ccc(OC(C)C)cc2)cc1 +CS(=O)(=O)NCc1ccc(NCc2ccc(Cl)c(F)c2)cc1 +Cc1ccc(C(=O)CCCC(=O)NCc2ccccn2)cc1 +CC(=O)c1ccc(C#CCNC(=O)c2ccc[nH]c2=O)cc1 +Cn1nc2nc(N3CCCC3)nc(-c3cccc(F)c3F)c2c1N +CCC(CC)C(=O)Nc1ccc(C)c(S(=O)(=O)NC)c1 +NC(=O)CCn1c(SCc2ccc(F)cc2)nnc1-c1ccco1 +Cc1ccc(NC(=O)COC(=O)c2ccccn2)cc1F +CCn1cc(S(=O)(=O)N2CCCc3cccc(NC(C)=O)c32)cn1 +O=C(c1cscn1)N1CCC2(C1)CN(C(=O)c1cscn1)C2 +COc1ccc(C(=O)N2CCN(Cc3ccccc3)CC2)nn1 +Cc1ccc(NCc2n[nH]c(-c3ccncc3)n2)cc1 +CS(=O)(=O)c1ccccc1SCc1cn2ccsc2n1 +NC(=O)c1ccccc1NC(=O)c1cccnc1N +CCOc1ccc2c(c1)CN(C1CC(C)OC1=O)CC2 +COc1ccc(Cc2nn3c(-c4cnccn4)nnc3s2)cc1 +CCOc1ccccc1C1C=NC(NC(C)=O)=CC(=O)N1 +COc1cc(C(C)NC(=O)Nc2cnn(C)c2)ccc1OC(C)C +CC(NC(=O)c1ccc2c(c1)CCC2)c1nnc2n1CCC2 +CC(C)c1nnc2n1CCN(C(=O)CN1CCc3sccc3C1)C2 +Cc1ccc(C(=O)N(Cc2ccccn2)c2ccncc2)c(C)c1 +Cc1cccc(OC(=O)Cn2ncc3ccccc3c2=O)c1C +CN1CCOC(CNC(=O)C2(c3ccccc3)CCC2)C1 +CCCOc1ccc(C(=O)N2CCCC2)cc1Br +Cc1ccc(C(C(=O)NCCN2CCCOC2=O)N(C)C)cc1 +N#Cc1ccc(F)c(CNC(=O)NC2Cc3ccccc3C2)c1 +Cc1cc(C)c(C(=O)N2CCCC2c2cc(C(C)C)on2)c(=O)[nH]1 +CCC=CCOC(=O)c1cccc(C(=O)N2CCCC2)n1 +Cc1cc(OCC(=O)NCCc2ccccn2)ccc1Cl +N#Cc1cccc(OCCCn2cc(Cl)cn2)c1 +COc1ccc2cc(CNC(=O)C3CCCO3)ccc2c1 +O=C(CC1C(=O)Nc2ccccc21)Nc1cc(Cl)cc(Cl)c1 +O=C1CC(C(=O)NCCc2cc3ccccc3o2)c2ccccc2N1 +Nc1c(-c2ccc(Cl)cc2)nc2ccc(CO)cn12 +OC(CNCc1nnnn1Cc1ccccc1)c1ccccc1 +O=C(c1cc(Cl)c[nH]1)N1CCn2c1nc1ccccc12 +CCCc1nc2ccccc2n1CC(=O)NCC1CCCO1 +Nc1ncnc2c(C3OC(CO)C(O)C3O)scc12 +O=C(NCCc1nc2ccccc2s1)c1cccnc1 +CC(=O)Nc1ccc(CC(=O)Nc2cc(-c3ccco3)no2)cc1 +Cc1noc(C)c1CC(=O)N1CCCC(N2CCOCC2)C1 +COc1cccc(C2CCCCN2C(=O)c2cccn2C)c1 +COc1ccc(-c2nnsc2C(=O)NC(C)C)cc1 +O=C(Cn1ccc(-c2cccs2)n1)N1CCc2sccc2C1 +O=C(COc1ccccn1)N(C1CCCC1)C1CC1 +Oc1ccc2c(c1Cl)C(C(O)c1ccccc1)NCC2 +O=C1CN(S(=O)(=O)c2ccccc2Cl)CCN1 +CCc1cc(C(=O)Nc2cc(Cl)ccc2C(N)=O)sc1C +O=C(COc1ccccc1-c1ccccc1)NCCO +COCCC(C)NC(=O)c1cc(Cl)c(OC)c(Cl)c1 +CC(=O)Oc1ccc(C(=O)NCc2ccc(Cl)cc2)cc1 +Cc1ccc2c(CC(=O)NC(C)(C)C)coc2c1C +COc1ccc(C(=O)N2CCC(O)(C(F)(F)F)C2)c(OC)c1 +Cn1cccc1CN(C(=O)Cc1ccc(F)cc1)C1CC1 +Cc1ccc(NCc2ccc(-n3cncn3)cc2)cc1C +Fc1ccc(CN2CCOCC2)c(Br)c1 +CNC(=O)c1ccc(NC(=O)NCC2CN3CCCCC3CO2)cc1 +Cc1noc(C)c1CN(C)S(=O)(=O)c1cnn(C)c1 +COc1ccc(-n2nnc(CO)c2C2CCCCC2)cc1 +CCCCNC(=O)c1cn(-c2ccc(Cl)cc2)nn1 +c1cc(CCc2nc(-c3ccncc3)no2)ccn1 +Cc1ccc(C(=O)NCC#Cc2ccc(C(N)=O)cc2)cc1 +N#Cc1ccc(CN(Cc2cccnc2)CC2CCCO2)cc1 +CCCCn1nnnc1Cn1cnc2cc(Cl)ccc2c1=O +Cc1ccnc(NC(=O)Cc2nc(-c3ccccc3)oc2C)c1 +Cc1cc(C(=O)N(Cc2cnc3ccccn23)C2CC2)c(C)o1 +O=C(Cn1ccnn1)Nc1ccc(Cl)cc1C(=O)c1ccc[nH]1 +CC1CN(C(=O)CNc2c(F)cccc2F)CC(C)O1 +N#CC1(NC(=O)C2CCC(NC(=O)C3CCCC3)CC2)CCCC1 +CN1CC2(CCN(Cc3nccs3)CC2)OCC1=O +CCC(CCO)NC(=O)Nc1ccc(Sc2ncccn2)cc1C +CS(=O)(=O)N1CC(C(=O)Nc2ccccc2Oc2ccccc2)C1 +Cc1cc(C(=O)Nc2ccc(F)c(S(=O)(=O)NC3CC3)c2)no1 +COc1ccc(C(=O)Nc2cccc3cccnc23)cc1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(NC(C)=O)cc1 +Cc1ccc(C2NCCc3c(N)cc(F)cc32)cc1F +FC(F)(F)c1ccc(CNc2cccnc2)cc1 +N#Cc1cccc(CNC(=O)Nc2ccc(Oc3cccnc3)nc2)c1 +O=C(Nc1ccc(Br)cn1)c1cccc(OC(F)F)c1 +CN(C)C(=O)c1cccc(N2CCC(C)(O)C(O)C2)n1 +CC(C)OC(=O)c1cc(CCc2ccccc2)nn1C +Nn1c(SCCOc2ccccc2)nnc1-c1ccncc1 +COc1ccccc1C(NS(C)(=O)=O)c1nccn1C +O=C(CCOc1ccccc1F)N1CCCCC1Cn1cccn1 +COC(=O)C(C)(C)NC(=O)C1CC1c1ccco1 +CCN(C(=O)C1CCCN(C(N)=O)C1)c1ccccc1 +CCOCCNS(=O)(=O)c1ccc(C2CNC(=O)C2)cc1 +O=C1COc2ccc(C(=O)NC3CCCCC3O)cc2N1 +COc1cccc2sc(C(=O)NCC(C)(C)C)nc12 +CS(=O)(=O)c1ccccc1NC(=O)NCc1ccco1 +N#Cc1cccc(CNC(=O)c2cc(Cl)ccn2)c1 +CS(=O)(=O)c1cc(C(=O)NC2CCCC2)c(Cl)cc1Cl +CC(C)=CCC1(CO)CCCN(C(=O)c2cc3c([nH]c2=O)CCC3)C1 +CCCc1cc(C(=O)NCCCN2CCOCC2)n(C)n1 +Cc1cccc(-n2ccnc2SCCN2CCOC2=O)c1C +CC(=O)c1ccc(NC(=O)NCC(=O)NC2CC2)cc1C +CCCNC(=O)c1cc2n(n1)CCCN(Cc1cccc(C)c1)C2=O +Cc1n[nH]cc1CNC(=O)c1c(Cl)cccc1Cl +CCN(CC)C(=O)c1cnc(COc2ccccc2)nc1N +COc1ccc(-c2noc(C3(C)CCOCC3)n2)cc1 +O=C(c1cc(F)cc(F)c1)N1CCc2cc(F)ccc2C1 +CCOc1ccccc1N1CCN(C(=O)c2cc(C)nn2C)CC1 +CCCN(CC(=O)Nc1cc(Cl)ccc1Cl)C(=O)COC +O=C(NCC1CC1)c1cnn2c1CN(Cc1ccc(F)cc1)CC2 +CC(C)(C)c1ccc(-n2nnnc2-c2ccc(N)cc2)cc1 +CC(C)COCC(NC(=O)c1ccc(=O)n(C)c1)c1ccco1 +Cc1ccc(C)c(CC(=O)NCCS(N)(=O)=O)c1 +Cc1cccc(NC(=O)NCC(O)c2cccc(F)c2)n1 +NS(=O)(=O)NC(c1ccccc1)c1ccncc1 +CC(C)n1ncc2cc(CNc3ccc(Br)cn3)cnc21 +CCOc1ccc2nc(C(=O)Nc3ccc(NC(C)=O)cc3)cn2n1 +COCc1ccccc1NC(=O)NCc1ccc(C(=O)N(C)C)cc1 +NS(=O)(=O)c1cnc(N2CCOC(c3ccccc3)C2)s1 +CN(CC(=O)N1CC(=O)Nc2ccccc21)c1ccc(F)cc1 +Cn1cc(CCCn2cc(N)cn2)c2ccccc21 +CCC(CC)NC(=O)CNC(=O)c1cccc(F)c1 +Cc1cc(Cl)ccc1NC(=O)NCc1cccnc1 +O=C(NCCCc1nc2ccccc2[nH]1)c1cnc2[nH]ccc2c1 +CN1c2ncccc2C(=O)NC1c1ccc(NC(=O)C2CC2)cc1 +O=S(=O)(Cc1ccon1)N1CCN(CC2CC2)c2ccccc21 +CCOc1ccc(OCC(=O)Nc2cc(F)ccc2F)cc1 +O=C(NCc1ccc(S(=O)(=O)N2CCOCC2)cc1)C1CC1 +CCOC(=O)CN(Cc1nc2c(oc3ccccc32)c(=O)[nH]1)C1CC1 +COc1cccc(CNC(=O)C(C)Oc2ccc(Cl)cc2)c1OC +COc1cc(NC(=O)N(C)Cc2ccccc2F)cc(OC)c1OC +Cc1cc(SCC(=O)Nc2nccs2)nc(=O)[nH]1 +CCCCN(C)S(=O)(=O)NC1CCc2cc(F)ccc21 +CN(C)c1ccc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)cc1 +CC(=O)N1CCC(NCc2cc(=O)c3c(C)ccc(C)c3[nH]2)CC1 +CC1(C(=O)N2CCCC2C(=O)Nc2ccccc2)CC1(Cl)Cl +Cc1ccc(C(=O)NCC(=O)Nc2nccs2)c(O)c1 +COc1ccccc1CC(C)CC(=O)NCc1cc(C)oc1C +CNC(=O)C(CC(C)C)NC(=O)NCc1ccc(-n2cccn2)cc1 +CCN1C(=O)C(c2nc3ccccc3[nH]2)C(O)c2ccccc21 +CC(C)NC(=O)c1cccc(OCc2ccccc2)c1 +COc1ccc(S(=O)(=O)NCC#Cc2ccc(N(C)C)cc2)cc1 +O=C(CCCNc1nc(C(F)F)nc2ccccc12)Nc1cn[nH]c1 +Cc1nonc1CC(=O)N1CCCC(c2cc3ccccc3cn2)C1 +Cc1nnc(SCC(=O)c2cn(C)c3ccccc23)s1 +Cc1cnn(CC2CCCN2C(=O)CCNS(C)(=O)=O)c1 +O=C(NCC(O)COCC1CC1)Nc1ccccc1F +Cc1nnc(COc2cccc(NC(=O)C(C)C)c2)n1C +CC(C)C(=O)NCCNC(=O)c1ccc(-c2ccccc2)cc1 +COc1ccccc1OCCC(=O)N1CCCc2cccc(OC)c21 +COc1ccccc1NC(=O)CCn1cnc2ccccc21 +CCc1ncc(C(=O)Nc2ccc(C)c3cn[nH]c23)s1 +COc1cccc(C2C(C(=O)OC(C)C)=C(C)Nc3ncnn32)c1 +Cc1ncc(CN(C)CC(=O)c2c(N)n(C3CC3)c(=O)[nH]c2=O)s1 +CS(=O)(=O)NC1CCCN(C(=O)c2ccc3ccccc3n2)C1 +Nc1ccc2[nH]cc(C(=O)NCCOCCO)c2c1 +Cc1cc(C(=O)N2CC(c3nc(-c4ccsc4)no3)C2)no1 +COc1coc(COC(=O)c2ccc(F)cc2)cc1=O +Cc1cccn2c(C(C)O)c(-c3cccs3)nc12 +Cc1cc(C(=O)OC(C)C(=O)c2ccc3c(c2)CCC3)c(C)o1 +Cc1cc(C)c(NC(=O)c2cc(-c3cccnc3)on2)c(C)c1 +Cc1nn(C)cc1S(=O)(=O)NCCc1ccc(F)cc1 +CCOC(=O)c1cn(-c2ccc(S(C)(=O)=O)cc2)nc1C +Cc1nn(C)cc1CCC(=O)NC(Cc1ccccc1)C1CC1 +CCC(CC(C)CO)NC(=O)Nc1cc(F)cc(N2CCCC2)c1 +CCN1CCN(C(=O)C(C)NC(=O)OC(C)(C)C)CC1 +Cc1cccc(NC(=O)CCOc2cccc(Cl)c2)n1 +CCC(C)C(NC(=O)c1cccc(C#N)c1)C(N)=O +COCCNC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1ccccc1NC(=O)Cc1nc(CO)cs1 +Cc1nc(C2CCN(C(=O)CCSc3ccccn3)CC2)no1 +N#CCCN(CCC#N)C(=O)COc1ccc(Cl)c(Cl)c1 +CCCN(CC(=O)OCC)C(=O)c1ccc2c(c1)CCC2 +CCOc1ccccc1NC(=O)C1CN(Cc2ccccc2)CCO1 +Cn1cnnc1-c1cncc(NCc2ccc(Oc3ccccc3)o2)c1 +CCOc1ccc(NC(=O)NCC(F)(F)F)cc1 +C=CCOC(C)C(=O)Nc1ccc(C(=O)NC)cc1 +Cn1ccsc1=NC(=O)c1cccc(NC(=O)C2CC2)c1 +Nc1cc(Cl)cc2c(C(=O)Nc3ccncc3)nccc12 +COC(=O)CNS(=O)(=O)Cc1ccc(Cl)cc1 +Fc1ccccc1Nc1ncc(Br)cn1 +Cc1ccc(-n2nnc3c(C(N)=O)ncn3c2=O)cc1 +CCn1nc(C)c(NCc2ccc3c(c2)OCCO3)c1C +N#Cc1cccnc1NCc1ccc(-n2cnc3ccccc32)nc1 +CCCOC(=O)c1ccccc1SCC(=O)N(C)C +NC(=O)C1CCN(C(=O)NC2CCSc3c(F)cccc32)CC1 +COC(=O)CCNC(=O)C(C)Oc1ccc(Cl)c(Cl)c1 +COc1cccc2c1CCC2NC(=O)Cc1ccc[nH]1 +Cn1ccc(NC(=O)COc2ccc3nc4n(c(=O)c3c2)CCC4)n1 +CCc1cnc(C(=O)NCC(=O)Nc2cccc3cccnc23)s1 +Cc1cc(C(=O)CCN2CCOCC2)ccc1F +c1cnc(CNc2ccc(-c3c[nH]cn3)cc2)cn1 +NC(=O)C1CCN(c2cnc3ccccc3n2)CC1 +Cc1ccccc1C(C)NS(=O)(=O)c1cccc2cnccc12 +CC(C)n1c(C2CCCN(C(=O)C3CCC3)C2)nn(C)c1=O +Cc1cc(C(F)(F)F)nn1CCCNC(=O)C1CCCO1 +Cc1n[nH]c(C2CN(Cc3noc(C(C)C)n3)CCO2)n1 +O=C(COC(=O)Cc1ccc2c(c1)OCCO2)NCC(F)(F)F +CCn1nc(C)c(-c2cc(C(=O)OC)n3ncc(C#N)c3n2)c1C +Cn1cnnc1C1CCN(C(=O)CCc2ccc(Cl)cc2)CC1 +CN(C)C(=O)CSc1nc2ccccc2c(=O)n1CC1CCCO1 +CN(C(=O)c1cccc2[nH]ncc12)C1CCN(c2ccccc2)C1=O +Oc1ccc(-c2c(-c3ccccc3)ncn2CCCn2ccnc2)cc1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)c2ccc(C#N)cc2F)c1 +O=C(NCc1nnc2n1CCC2)C1CC1c1ccc(F)cc1 +COc1ccc(NC(C)=O)cc1-c1nc(C)cc(N)n1 +O=C(NCC1CC1)C1CC(=O)N(c2cc(Cl)cc(Cl)c2)C1 +Clc1cc2c(cc1Cl)C(c1ccoc1)NCC2 +CC(Cn1nc(-c2cccs2)oc1=O)NC(=O)C1CCCCC1 +O=C(c1cnc2ccccc2n1)N1CCN(CC2CCCO2)CC1 +O=C1Nc2ccc(S(=O)(=O)NCc3cccnc3)c3cccc1c23 +COc1ccc(C(O)C(C)NC(=O)CC2CCC(OC)CC2)cc1 +Cc1c[nH]c(=O)n1-c1ccc(C(=O)NC2CC2)cc1 +C=CCCC(=O)N(CC(=O)N1CCCCC1)c1ccccc1 +CCC(C)(C#N)NC(=O)c1ccc(-n2nc(C)cc2C)c(F)c1 +CC(=O)OCCSc1nc2c(=O)n(C)c(=O)n(C)c2n1C +O=C(CNC(=O)c1ccccc1F)Nc1ccc2ccccc2n1 +O=C(CCc1nc(-c2ncccn2)no1)Nc1ccc2ccccc2n1 +O=C(Nc1cccnc1)Nc1cccc(OCc2cccnc2)c1 +CCCCOc1cccc(CNC(=O)N2CCOCC2)c1 +CCC(C)N(CCOC)C(=O)c1cc(Cl)ccc1N +CC(C)CCNC(=O)Cc1csc(N2CCNC2=O)n1 +Cc1occc1C(=O)NC(C)c1ccc(F)c(Cl)c1 +Cc1ccc(S(=O)(=O)NCCc2ccc(F)cc2F)s1 +Cc1cn2cc(C(=O)NCc3ccc4c(c3)CCCO4)ccc2n1 +Cc1ccc(C(N)=O)c(OCC(=O)N(Cc2ccc(C)o2)C2CC2)c1 +COc1cccc(CNC(=O)CCC(C)(C)C)c1OC +CCc1nc(C(C)NC(=O)NCc2cc(C)no2)cs1 +Cc1cc2[nH]c(=O)[nH]c2cc1S(=O)(=O)NCCO +O=C(NC1CCC1)C1CC2(CCCN(c3nncs3)C2)CO1 +NC(=O)C1CCCCN1C(=O)Cc1ccc(-c2ccccc2)cc1 +CCOC(=O)c1ccc(NC2CCCc3c2cnn3CCO)nc1 +O=C(Cc1cccs1)Nc1nnc(Cc2ccccc2)o1 +Cn1nccc1CNC(=O)Nc1ccc(F)c(F)c1F +Cc1cccc(CN(C(=O)C2CCN(C(=O)C(C)C)CC2)C2CC2)c1 +CC(O)C(=O)N1CCc2[nH]nc(-c3ccccc3F)c2C1 +CC(=O)Nc1cccc(C(=O)NCCc2cccc(Cl)c2)c1 +CC(O)C(NC(=O)C1CCCC1)C(=O)NCC1CCc2ccccc21 +Cc1ccc(C(=O)Nc2cccc(NC(=O)c3ccncc3)c2)cc1 +Cc1cc(C)c(CN2CCn3c(nn(C)c3=O)C2)c(C)c1 +COc1ccc(C(=O)CCC(=O)N2CCNCC2)c(OC)c1 +O=C(CCN1CCCC1=O)NC(c1nccs1)C1CC1 +CC1CCCC1NC(=O)NCC(C)(O)c1ccccc1 +O=C(Cn1cnc2ccccc2c1=O)c1cccc2ccccc12 +C1CCC(CSc2nnc(NCC3CCCO3)s2)C1 +COc1ccc(CN(C)C(C)c2sc(C)nc2C)cc1SC +Cc1cnn(C2CCCN(C(=O)c3cccc4c3OCO4)C2)c1 +CN(CCNC(=O)Nc1nnc(C(C)(C)C)s1)c1ccccc1 +COc1ccc(C(=O)N(C)Cc2nnc3ccccn23)cc1OC +Cc1nc2ncccn2c1-c1csc(Nc2ncccn2)n1 +CN(C(=O)c1cc2ccccc2o1)c1ccccn1 +CN(C)C(=O)C1CCC(CNC(=O)c2ccco2)O1 +CN(C)C(=O)C(C)(C)c1cccc(Br)c1 +O=C(CSc1nc(=O)[nH]c2c1CCC2)N1CCCCC1 +O=C1CC(c2cc3ccccc3[nH]2)c2c(nc3ccccn23)CN1 +COc1cc(CNC(=O)N2CCCC(C)CC2)ccc1OCCO +CC(c1ccccn1)N(C)C(=O)c1cccc(-c2ccoc2)c1 +CCOC(=O)c1c(NC(=O)C2CC2)sc2c1CCN(C(C)=O)C2 +Cc1noc(NC(=O)c2ccc(Cn3ccnc3)cc2)n1 +CC(=O)n1c(=O)n(-c2ccccc2)c(=O)c2c3c(sc21)CCCC3 +Cc1cccc(NC(=O)CN(C)c2ccc3nccnc3n2)n1 +Cc1cnc(C(C)NC(=O)c2ccc(-c3cscn3)cc2)s1 +CCn1cc(NC(=O)Nc2c(C)noc2C)ccc1=O +COc1cc(OC)cc(C(=O)Nc2nc3c(s2)CNC3)c1 +CC1(C)CCC(NC(=O)c2cc[nH]n2)c2ccccc21 +CCN(CC)C(=O)c1nc(CNC(=O)c2ccco2)oc1C +Cc1c(N)cc2c(=O)cc(C(=O)NCCC(C)C)oc2c1C +CCCOc1ncccc1CNC(=O)Nc1ccc(OC)cc1Cl +O=C(CCCNC(=O)C1CC1)Nc1cnn(-c2ccccc2Cl)c1 +CCCn1nc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)ccc1=O +Cc1c(C(=O)OC(C)C)sc(NC(=O)C2CC2)c1C(N)=O +CC(C)Cn1c(=O)c(C(=O)N(C)C)nc2cccnc21 +Cc1nn2cccnc2c1C(=O)Nc1ccc(Cn2ccnc2C)cc1 +CCCc1ccc(C(=O)CNS(=O)(=O)N(C)C)cc1 +Cc1cc(C(=O)Nc2cccc(COC(=O)c3cc(C)on3)c2)no1 +COCC(C)NC(=O)C1CCN(c2ccccc2F)CC1 +CC1CCCN(C(=O)NC(C)c2ccc(N3CCCC3=O)cc2)CC1 +Cc1cccc(CC2Oc3cc(N)ccc3N(CCCO)C2=O)c1 +CCC(NS(=O)(=O)CC)c1cccc(Cl)c1 +Cc1noc(C)c1C(=O)NC(C)Cn1nc(-c2cccs2)oc1=O +O=C1N(CC2CC2)CCC12CCCN(c1ncc(F)cn1)C2 +Cc1csc(S(=O)(=O)CC(=O)N(C)Cc2ccc(F)cc2)n1 +COc1ccccc1-c1nnc(NC(=O)C(C)(C)C)s1 +CCNC(=O)c1cc(S(=O)(=O)N2CCCCC2)ccc1F +O=C(Nc1cccc(-c2nnco2)c1)c1cccnc1N1CCCC1 +Cc1nnc(NC(=O)Cn2nnc(CO)c2C(C)(C)C)s1 +Cc1cc(Cl)cc(C(=O)c2cnc(N)nc2)c1O +COc1ccc(CN2CCN(c3nn4cc(C)nc4s3)CC2)cc1 +Cc1ccc(C(=O)CCN2CCc3ccccc32)cc1N +CC(=O)Nc1nc2c(C)cc(NC(=O)CC3CCCC3)cc2s1 +COc1ccc2ccc(Oc3ccc4nnnn4n3)cc2c1 +O=C(c1ccco1)N1CCCC1C(O)c1nccs1 +CCC(=O)c1sc(Nc2cccc(F)c2)nc1N +Cn1cccc1C1CCCCCN1C(=O)CNC(=O)c1ccccc1 +Cc1ccc(S(=O)(=O)CCc2ccccc2)cc1 +COc1ccc(Cc2n[nH]c(-c3cccc(N)c3)n2)cc1F +Cc1csc(CNC(=O)COCC2CCCO2)n1 +Cc1n[nH]c(C)c1CNC(=O)c1cccc(N(C)C)c1 +COc1ccccc1CNC(=O)c1c(-c2cccc(F)c2)noc1C +CCN(C)C(=O)CNCc1ccc(OC)c(OC)c1 +COc1ccc(CC(=O)N2CCCC(n3cncn3)C2)cc1OC +CCn1ncc(-c2cc(Cl)ccc2C)c(CC#N)c1=O +Cc1csc(C2CCCCN2C(=O)C2CC2c2cccc(F)c2)n1 +CNC(=O)Cn1c(-c2cccs2)cc2cc(Cl)ccc21 +CCC(CC)C(=O)n1ccn(S(=O)(=O)c2ccc(C)cc2)c1=O +Cn1ncc2c(SCc3ccc4ccccc4n3)ncnc21 +Cc1ccc(CC(=O)Nc2ccc(C)c3cn[nH]c23)s1 +COC1CCN(C(=O)Cc2c(C)nc(-c3ccccn3)[nH]c2=O)CC1 +COc1ccc(SCC(=O)N2CCOCC2)cc1 +Cc1cccnc1NC(=O)C(C(F)(F)F)C(F)(F)F +O=C(Nc1ccc(Oc2cccnc2)nc1)c1ccc2c(c1)CCC2 +Cc1ccc(CC(=O)N(c2ccccc2)C(C)C)cn1 +CNc1c(F)cc(C(=O)Nc2nccs2)cc1F +Cc1cnc(NC(=O)C(C)Sc2nncn2C)s1 +CCC(C)C(=O)Nc1ccc(C(=O)NC(C)C)cc1 +O=C(NC1CC1)C(Sc1ncnc2ccccc12)c1ccccc1 +O=C(c1ccc2cc[nH]c2c1)N1CCC(Nc2cccnn2)CC1 +CC(=O)c1c(C)nc(C)nc1SCCOc1cccc(C#N)c1 +COc1ccc(C(=O)COc2ccc(F)cc2)c(O)c1 +COc1ncccc1CNC(=O)Cc1ccc(F)c(F)c1 +CCOC(C)c1nccn1Cc1coc(-c2ccc(F)cc2)n1 +Cn1c(CSc2nnc3n2CCCCC3)nc2ccccc2c1=O +Nc1ccc(-c2nc(-c3ccsc3)cs2)cc1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1ccc2[nH]cnc2c1 +N#Cc1cccc(CSc2nnc(-c3ccc(F)cc3)n2N)c1 +N#CC1CCCC1NC(=O)C1Cc2ccccc2O1 +Cc1cc2c(c(C(O)COc3ccccc3)c1)NC(=O)C2 +CC(NC(=O)c1ccco1)C(=O)OC1CCCCCC1 +CCC1Nc2cc(Br)ccc2N(CCC#N)C1=O +Cc1cnn(Cc2ncc(-c3cccc(F)c3)o2)c1 +CC(c1cccs1)N(C)C(=O)Cc1ccc(O)cc1 +CC1CCCCN1C(=O)CCn1c(=O)oc2ccccc21 +O=C(NC1CC1)C(NCc1nnc2n1CCCC2)c1ccc(F)cc1 +COc1ccc(OC)c(CC(=O)Nc2ccc(C)cc2F)c1 +COc1cccc(N2C(=O)CN(Cc3c[nH]c4ccccc34)CC2C)c1 +Cc1c(NC(=O)NC2CCCC2)cccc1S(=O)(=O)NC1CC1 +CC1(c2ccccc2)CCCN(c2ncccc2C(=O)N2CCCC2)C1 +COC(=O)CCC(=O)NC(C)C(C)(C)c1ccccc1 +CN(C(=O)CCNS(=O)(=O)c1ccccc1)c1ccc(F)cc1 +COCCn1cc(NC(=O)C2CCN(C(=O)c3ccoc3)CC2)cn1 +O=C(Nc1ccccc1)Nc1ncnc2nc[nH]c12 +O=C(Nc1ccccc1)NC1CCN(C(=O)C2CC2)CC1 +O=S(=O)(c1ccccc1)n1ccc2c(Br)ccnc21 +CC(C)CN(CCC#N)c1c(N)n(CC(C)C)c(=O)[nH]c1=O +Cc1oc(C(=O)NCCc2ccc(Cl)cc2)cc1S(N)(=O)=O +CC(C)c1cc(C(=O)N(C)Cc2cn[nH]c2-c2ccc(F)cc2)no1 +COc1ccc(NC(C)=O)cc1NC(=O)COC(=O)c1ccccc1 +CCc1nnc(NC(=O)NCc2cccc(F)c2)s1 +CC1COCC(C)N1C(=O)CS(=O)(=O)c1ccc(Cl)cc1 +NC(=O)c1ccc(C(=O)Nc2cccc3ncccc23)cc1 +Nn1c(SCC(=O)Nc2ccccc2F)nnc1-c1ccccc1 +Cc1cc(C)c2nc(N3CCCC3)c(C#N)cc2c1 +CC(O)c1nc2ccc(F)c(F)c2n1C(C)(C)C +Cc1nc(CCNc2cccc(F)c2)sc1C +CCOC(=O)C1CCCN(c2cc(F)ccc2F)C1 +Nc1nccnc1C(=O)NCC(O)c1ccc2ccccc2c1 +CC(=O)c1cc(C(=O)NCCNC(=O)c2ccc(F)cc2)n(C)c1 +O=C(c1ccnnc1)N1CCC2(CC1)CCN(c1ccccc1)C2=O +CC(NC(=O)Nc1ccc2c(c1)COC2)C(=O)NCc1ccco1 +O=C(CN1CCN(c2nnnn2-c2ccccc2)CC1)N1CCCC1 +CC(=O)c1ccc(NC(=O)NCc2cccc(C(N)=O)c2)cc1C +O=C(Cc1ccc(Cl)cc1)N1CCC(Oc2ccccc2)CC1 +CCOc1ccc(-c2nc(C#N)c(NCCN3CCOCC3)o2)cc1 +CCOCC(=O)NC(C)c1ccc2ccccc2c1 +N#Cc1coc2cc(OCc3ccccc3)ccc2c1=O +CCN(CC)C(=O)CCC(=O)N1CCCC(NC(C)=O)C1 +O=C1CCCN1c1ccc(NCc2ccccc2Br)cc1 +CC(C)CN1CC(C(=O)NCc2nc(-c3ccccc3)no2)CC1=O +COc1cc(C(=O)Nc2cccc(Cl)c2)cc(OC)c1OC +COc1ccc(SC(C)C(=O)N2CCNCC2)cc1 +CC(=O)c1ccc(C#CCNC(=O)NC2CCCCC2)cc1 +COc1ccc(NC(=O)C(Sc2cc(C#N)ccn2)C(C)C)cc1 +CCn1c(=O)c2c(ncn2CC)n(-c2cccc(OC)c2)c1=O +Nc1ccc(Cl)c(-c2nnc(C3CCCC3)o2)c1 +COC(=O)CCN(C)C(=O)c1cc(Cl)ccn1 +CCCn1c(C)nnc1SCC(=O)Nc1cccc(SC)c1 +Cc1cc(NC(=O)N2CCN(c3cccc(C)c3C)CC2)no1 +CCN(CC)C(=O)C1CCCN1Cc1ncccc1C(F)(F)F +CC(C)C(C)CC(=O)NC(Cc1ccccc1)C(=O)N(C)C +COc1ccnc(N2CCC(Cn3cc(C(C)(C)O)nn3)CC2)n1 +CCCOc1cc(NC(C)(C)C)nc(COC)n1 +O=c1cc(CN2CCCc3cc(F)ccc32)nc2ccccn12 +Cc1cc(C)nc(C(C#N)C(=O)CCc2c(C)nc3ncnn3c2C)n1 +Cc1ccncc1NC(=O)NCC(=O)N1CCCC1 +c1coc(Cn2cnnc2SCc2nnc(-c3cccs3)o2)c1 +CC(=O)NCc1ccc(C(=O)N(C)c2ccc3ccccc3c2)s1 +Cc1cccc(C)c1OC1CN(C(=O)C2CCOCC2)C1 +O=C(CNC(=O)c1ccc(F)cc1)c1ccc2c(c1)CCC2 +CCOc1cc(C)ccc1NC(=O)NCc1ncn(C)n1 +COC(=O)CN(C(C)C)S(=O)(=O)c1ccc(F)cc1 +CC(C)(C)n1cc(C#N)cc1NC(=O)c1ccoc1 +CS(=O)(=O)N1CCC(NC(=O)NC2COc3ccccc32)CC1 +Cc1ccc(C(=O)CCC(=O)NCCc2ccccc2)s1 +Cn1cc(-c2ccncc2)cc1C(=O)NCc1ccc2c(c1)OCO2 +CC(NS(C)(=O)=O)C(=O)N1CCC(c2ccccc2)CC1 +CC(=O)N(CCc1ccccc1)CC(=O)N(C)Cc1ncnn1C +Cc1ccc(=O)n(CC(=O)NCCOc2ccccc2)n1 +COc1cccc(NC(=O)c2nnn(Cc3ccc(F)cc3)c2N)c1 +COc1cccn(CC(=O)N(C)CCOc2cc(C)cc(C)c2)c1=O +COCC(=O)Nc1ccccc1COc1ccccc1 +O=C(CCc1cc(Cl)cs1)Nc1cnn(CC(F)F)c1 +COc1ccccc1C(=O)N1CCCN(C(=O)OC(C)(C)C)CC1 +COc1c(CNCc2ccc(-n3ccnc3)nc2)c(C(C)C)nn1C +CCOCCCNC(=O)C1CCN(C(=O)C2CCCC2)CC1 +Cc1cc(N)ccc1NC(=O)CSc1ccccc1F +CCCNC(=O)c1cccc(C(=O)Nc2ccc(NC(C)=O)cc2)c1 +CCCCNC(=O)C(N)c1ccc(O)cc1OC +NC(=O)c1cc(-c2ccccc2)sc1NC(=O)C1CC1 +Cc1ccc(N(C(=O)c2cnn(-c3ccncc3)c2C)C(C)C)cc1 +CC(C)(C)NC(=O)CNC(=O)C(C)(C)c1ccccc1 +COc1ccccc1-n1ccnc1SCC(=O)NCc1ccco1 +COCCN(C)c1ccccc1CNc1ncnc2ncccc12 +CCOC(=O)N1CCN(c2ccc(N)c(OC)c2)CC1 +COC(=O)CNC(=O)Cc1cccc(OC(C)C)c1 +O=C(c1ccc(Cl)cc1)N1CC(c2nc(-c3ccccn3)no2)C1 +COC(=O)Cn1cnc(-c2ccccc2Cl)n1 +CCn1cnc2cc(C#N)cc(Br)c21 +N#Cc1c(N)nc(-c2ccc(C(F)(F)F)cc2)c(C#N)c1C#N +CCc1ccccc1-n1c(C)nc2ccccc2c1=O +CCOCCCOc1ccc2ccccc2c1CO +CCOC(=O)C(C)NC(=O)CNC(=O)c1ccsc1 +N#Cc1cccc(C(=O)N2CCC(C(=O)N3CCCCCC3)CC2)c1 +CC(C(=O)Nc1ccccc1C(=O)N1CCOCC1)c1cccs1 +COc1ccc(Cl)cc1NC(=O)NCC(O)c1ccsc1 +Cc1cccc(CC2(NC(=O)C3CC34CC4)CC2)c1 +CCn1c(CNC(=O)C2CCOC2)nc2ccccc21 +CC(CC(O)c1cccs1)NC(=O)Nc1cccc2cccnc12 +CC(=O)N1CCC(C(=O)Nc2cccc(-c3nccs3)c2)CC1 +CCN(C)C(=O)c1ccc(OCc2c(C)noc2C)c(OC)c1 +COc1ccc(S(=O)(=O)N2CCOC3CCCCC32)c(C)c1 +Cc1cc(C(=O)NCC(C)C)c(C)n1Cc1ccco1 +CS(=O)(=O)c1ccc(C(=O)OCc2ccccc2C#N)cc1 +CCOCCNC(=O)NCc1ccc(C(=O)N(C)C)cc1 +CCCN(Cc1ccccc1)C(=O)Cc1ccc[nH]1 +COc1ccc(Cc2nc(C(C)C)c(C#N)s2)cc1OC +Cn1ccc(C(=O)Nc2ccnc3ccnn23)cc1=O +COc1ncccc1NC(=O)N(C)Cc1sccc1C +Cc1nc(NC(=O)Cn2c(=O)n(C)c3ccccc32)sc1C +CCOc1ccc(C(=O)C2CC2)cc1Br +C=CCn1nnc(NC(=O)COc2ccccc2)n1 +CN(c1ccc(O)cc1)c1cnc2ccccc2c1 +COc1ccccc1CNC(=O)c1ccc2c(c1)nc(C)c(=O)n2C +Cc1cc(C)c(CNC(=O)CCNC(=O)OC(C)(C)C)c(C)c1 +CCc1nnnn1CC(=O)Nc1ccc(F)cc1F +COc1cccc(COCC(=O)N2CCN(CC(C)(C)O)CC2)c1 +Brc1cnn(-c2cccc3[nH]cnc23)c1 +CCOc1cc(-c2nc3sc(C)c(C)c3c(=O)[nH]2)ccc1O +COCc1oc2c(c1-c1nnc(NC(C)C)s1)CCCC2 +CSc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cn1 +CC12CCC(C(=O)Nc3ccccc3C(F)(F)F)(OC1=O)C2(C)C +Cc1cccc(NCc2c(C)nn(CCO)c2C)c1C +Cn1ccc(NC(=O)c2nc(N)ccc2Cl)n1 +COc1ccc(OC)c(C(C)NC(=O)CSc2ncccn2)c1 +COC(=O)c1ccc2c(c1)CCN2C(=O)c1cnc(C)cn1 +CC(C)c1ncc(Cl)c(C(=O)N2CCCC2c2ccc[nH]2)n1 +Cn1cc(C(=O)COc2cccc(F)c2)c2ccccc21 +COC(=O)CCCC(=O)c1cc(C)c(C)cc1OC +Cc1cc(Cl)ccc1NC(=O)C(C)NC(N)=O +N#CC1(NC(=O)C2CC2c2ccc3c(c2)OCCO3)CC1 +Cc1nc(-c2ccc(NC(=O)C3CCC3)cc2)oc1C +O=C(CN1CCc2sccc2C1)OCc1ccoc1 +CCOc1c(Cl)cccc1NC(=O)NCC(=O)NCC(C)C +Cc1nnc(NC(=O)C(c2ccccc2)n2cnnn2)s1 +CN(C)C(=O)C1(C)CN(C(=O)c2cscn2)CCO1 +Cc1nc(CN2CCC3C2CCN3c2nncs2)cs1 +CCCc1nc(C)c(C(=O)N2CCN(c3ncccn3)CC2)s1 +CC(=O)c1ccc(NC(=O)c2ccncc2F)cc1 +COc1ccc(C(C)NC(=O)CCc2ccccc2)cc1OC +CC(C)(C)n1cc(C(=O)NCc2ccc(F)cc2)cn1 +O=C(Nc1ccc2c(c1)OCO2)N1CCC(Oc2ncccn2)CC1 +CCOC(=O)c1ccccc1NC(=O)c1ccnn1C +O=C(c1ccnc(-n2cncn2)c1)N1CCC(c2ccccc2)CC1 +CC(=O)N1c2ccc(NC(=O)C3(C)CCCO3)cc2CC1C +COC(=O)c1ccc(CN(C)Cc2c(C)noc2C)cc1F +CC(C)(C#N)C(=O)NCCC(=O)N1CCN(c2ccc(F)cc2)CC1 +CC(C)c1c(C(=O)NCc2ccncc2)cnn1Cc1ccccc1 +COc1ccc(OCCc2nnc(NC(C)=O)s2)cc1 +CCCCN(C)C(=O)c1ccc(OC)c(Br)c1 +O=C(c1ccc(NC2CC2)nc1)N1CCCC1c1ccccn1 +COc1ccc(Cl)c2sc(NC(=O)c3cnccn3)nc12 +O=C(c1cccc(-n2cccc2)c1)N1CCC(Cn2cccn2)CC1 +CCCNC(=O)CSc1nnc2c3cc(C)ccc3n(C)c2n1 +O=C(NCc1nc(-c2cccs2)no1)c1ccc(F)cc1F +CC(OC(=O)c1cccc(C#N)c1)c1nccs1 +Cc1cccc(-c2ncccc2CNC(=O)c2cccs2)c1 +CS(=O)(=O)NC1CCN(C(=O)c2ccco2)C1Cc1cccnc1 +Cc1ccc(NC(=O)C(O)c2ccc(F)cc2)cc1C +NC(=O)CSc1nnc(-c2ccncc2)n1Cc1ccco1 +COc1cccc(NC(=O)C2CN(C(=O)c3cc(C)on3)C2)c1 +CCN(CC)C(=O)NCc1ccc(N2CCCC2=O)cc1 +N#Cc1ccc(CNC(=O)c2ccc3cc[nH]c3c2)cc1 +Cn1cccc1C(O)CNC(=O)Cc1ccc(Cl)cc1 +CCn1nnc(NC(=O)Cn2ncc(N3CCCCC3)cc2=O)n1 +CC(C)(C)OC(=O)N1CCCCC1CNC(=O)Nc1ccccc1 +O=C(c1cnc2ccccc2c1C(F)(F)F)N1CCC(O)CC1 +O=C(c1ccccc1Cl)N1CCC(c2nnc(C3CC3)o2)CC1 +CCc1cccc(C)c1NC(=O)C1CCN(C(=O)c2ccco2)CC1 +CC(NC(=O)NCc1cccnc1)c1ccccc1 +CCCNC(=O)c1cccc(NC(=O)NCc2ccncc2)c1 +Cc1ccc(CCC(=O)NC(C)C(=O)N2CCCCC2)cc1 +COc1cc(CO)cc2c1OC(C)C(=O)N2CC(C)C +COc1ccc(-c2noc(NCCc3nc4ccccc4n3C)n2)cc1 +Cc1nnsc1C(=O)N1CCN(CCn2cccn2)CC1 +Cc1cc(C)c(C(O)CNCc2ccc3c(c2)OCO3)c(C)c1 +Cc1ccc(CC(=O)Nc2ccc3nccnc3c2)s1 +CCN(CCC#N)C(=O)CSc1nnc2n1CCCCC2 +Cc1cc(C)c(NC(=O)c2ncc3ccccn23)c(C)c1 +COc1ccccc1-n1nnc(C(=O)NC(C)(C)C(N)=O)c1C +CC(C)(C)Oc1cc(CNC(=O)Cc2ccon2)ccn1 +O=C(Nc1ccc2ncnc(N3CCCCC3)c2c1)c1ccsc1 +CCC(C)NC(=O)C(C)NC(=O)C1(C)CC1(Cl)Cl +CCOc1cccc(NC(=O)N2CCC(OCC(C)C)CC2)c1 +CCCc1nnc(NC(=O)c2ccc(-n3nccc3C)cc2)s1 +CCOC(=O)c1ccccc1NC(=O)c1sc(C)nc1C +CCn1nccc1NS(=O)(=O)c1cc(C)ccc1OC +CCOc1ccc(C(=O)N2CCCC(O)C2)cc1OC +COCC(=O)N1CC2CN(Cc3cccnc3)C(=O)C2C1 +Cc1cc(C(F)(F)F)nc(SCC(=O)N2CCOCC2)n1 +CSc1nc(N)nc2nc(N3CCCC3)[nH]c(=O)c12 +COc1cccc2sc(NC(=O)N3CCC(C(N)=O)CC3)nc12 +CN1C(=O)CC(NC(=O)c2ccc(O)cc2F)C1c1ccc(F)cc1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)Nc1ncccc1C)O2 +COc1ccc(C(O)CNC(=O)NCc2c(C)cc(C)[nH]c2=O)cc1 +Cc1ccc(Cl)cc1NC(=O)Cn1ccc2ccccc2c1=O +Cc1ccc(CNC(=O)CC2C=CCC2)c(OCC2CCOC2)c1 +Cc1ccc(NCc2cc(=O)n3c(C)csc3n2)cc1 +OCc1ccc(C2NCCc3c(F)ccc(Cl)c32)cc1 +COc1ccc(N(Cc2ccco2)C(=O)c2cnn(C)c2N)cc1F +COCCN(C)S(=O)(=O)N(C)C1CCCCC1C +COc1nc2ccccc2nc1C(=O)Nc1cc(F)ccc1F +COc1ccc(F)c(NCc2ccc(S(=O)(=O)C(F)F)cc2)c1 +N#CC12C(N)=NC3(OCCO3)C1(C#N)C2c1cccc(Cl)c1 +CCC(CC)c1nnc(NC(=O)CNC(=O)OC)s1 +CCCC(C)c1nnc(NC(=O)c2cnc3cc(=O)[nH]n3c2C)s1 +COc1cc(-c2cc(C(C)=O)c(C)n2C)c(OC)cc1C +COC(=O)c1c(C(N)=O)c(C)n(NC(N)=O)c1C +O=C(Nc1n[nH]c2ccccc12)c1ccccc1Cl +CC(NC(=O)CCn1cncn1)c1ccc(-c2ccccc2)cc1 +CN(Cc1ccc(Cl)cc1)C(=O)C1CCC(=O)N1 +O=C(CCNc1cnc2cnccn12)NCc1cccc(Cl)c1 +N#CCCCOc1cccc(NCc2ccc(F)c(F)c2)c1 +CCOC(=O)C1=C(C)N=C(C)C1S(=O)(=O)NC(C)C +CC(=O)Nc1ccc(SCc2csc(C)n2)cc1 +Cc1ccnc(C(NC(=O)C2CC=CC2)C2CC2)n1 +Cc1cc(Oc2ccccc2F)nc(C2CCN(C(=O)C(C)C)C2)n1 +COc1ccccc1OCc1nc(C(=O)NCC(C)C)cs1 +Cc1ccc(N(C)S(=O)(=O)c2cccc(Cl)c2)cc1N +CC(=O)c1cc2c(cc1NC(=O)CCCc1ccccn1)OCO2 +Cc1nn(-c2nnnn2-c2ccccc2)c(C)c1Br +Cc1noc(C2COCCN2C(=O)c2coc(-c3ccccc3)n2)n1 +CC(CC(=O)OCC(=O)N1CCCC1)c1ccccc1 +CCC(NC(=O)Cc1c(F)cccc1F)c1ccncc1 +O=C(Cc1cc(-c2ccc(Cl)cc2)on1)NCc1ccccn1 +CCN(CCO)c1ncnc(Nc2ccccc2F)c1N +O=C(c1ccc(-n2ccnc2)cc1)N1CCOCC1 +Cc1ccnc(N(C)C2CCCN(C(=O)OC(C)(C)C)C2)n1 +C=CCNC(=O)c1ccc(NS(=O)(=O)CC)cc1 +COc1cc(OC)c(OC)cc1CNc1cccc(C#N)c1 +O=C(CCNC(=O)c1cncc2cnccc12)Nc1ccccc1 +O=C(Nc1ccccc1-n1ccnc1)c1ccc2c(c1)OCCCO2 +CC(C)(C)OC(=O)N1CCN(c2ccc(Cl)c(N)c2)CC1 +O=C(COc1ccc(-n2cccn2)nn1)Nc1cccnc1 +Cc1[nH]c2ccccc2c1S(=O)(=O)CCNC(=O)NC(C)(C)C +Cc1cc(C(=O)Nc2ccc(-n3ccnc3C3CC3)cc2)co1 +Cc1cc(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)ncn1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)N(C)CCOCC3CC3)c12 +CC(=O)Nc1nc(CSc2ccc(F)cc2)cs1 +Cc1nc(SCC(=O)Nc2ccccc2F)[nH]c(=O)c1C +Cc1cnn(CC(=O)NC(C)Cc2cccc(Br)c2)c1 +COCC1CCCN(C(=O)Nc2cc(OC)cc(OC)c2)C1 +COC(=O)c1cccc(NC(=O)c2ccc(C(C)=O)s2)c1 +CC(=O)Nc1ccc(NCc2ccc3c(c2)CCO3)cc1 +COCCOCC(=O)N(C)c1cc(C)ccc1C +O=C(NCCCc1nc(-c2cccs2)no1)c1ccc(F)cc1F +CCOC(=O)C1CCCCN1Cc1c[nH]nc1-c1ccc(F)cc1F +Cc1noc(C)c1CCC(=O)OCCn1c(=O)oc2ccccc21 +COCc1nc(CCOc2ccc(F)cc2)sc1CO +CC(=O)c1csc(-c2csc(-c3cccc(C(N)=O)c3)n2)c1 +O=C(NCCCN1CCCC1=O)c1cccc(Br)c1 +O=C(NC1c2ccccc2CC1O)c1c(O)cc(F)cc1F +O=C(NCc1ccccn1)NCC1CN2CCCCC2CO1 +O=C(NCc1ccoc1)Nc1ccnn1C1CCCCC1 +CC1CCCN(c2ncc3c(n2)CN(Cc2cccc(F)c2)C3=O)C1 +Cc1ccc(C)c(OC(C)C(=O)N2CCC(=O)CC2)c1C +O=C(Nc1ccc(F)c(F)c1)C1CC2CCCC(C1)C2=O +COc1ccc2c(c1)CCCN(C(=O)NCCN1CCOCC1)C2 +Cc1cn(-c2ccccc2Cl)nc1NCc1cccn1C +CC(Cc1c(F)cccc1F)NC(=O)COc1cccc(C#N)c1 +OCCN(Cc1cccs1)Cc1ccccc1Cl +CC(=O)Nc1ccc(OCC(=O)NC(c2ccccc2)C2CC2)cc1 +NC(=O)Cn1cc(NC(=O)NCC(O)c2ccc(F)cc2)cn1 +O=C(NCc1nc(-c2ccco2)n[nH]1)c1nccn2ccnc12 +NC(=O)CCn1nnc(-c2cc3ccccc3o2)n1 +CCN(CC(F)(F)F)C(=O)c1cc(F)c(F)cc1Cl +Cc1ccc(C(=O)Nc2cccc(C)c2C(N)=O)c(C)n1 +CCc1cccc(NC(=O)Cn2c(C)cc(-c3nnc(C)o3)c2C)c1 +Cc1cc(CN(C)C(=O)NCc2ccccc2F)no1 +Cc1n[nH]cc1CNC(=O)CSc1nnnn1C1CC1 +N#CCSc1nc2ccccc2c(=O)n1Cc1cccnc1 +Cc1cc(NC(=O)NCCCOC2CCCC2)ccc1-n1cnnn1 +CC1CCCC(C)N1C(=O)c1ccc(-c2cscn2)cc1 +COC(=O)c1noc(C(=O)Nc2ccc(F)cc2F)c1N +CC(C)(CNC(=O)NCc1ccc(O)c(F)c1)c1ccncc1 +COc1ccccc1C(C)NC(=O)Cn1nc(C)c(C)c(C#N)c1=O +CCn1c(CC(=O)Nc2ccc(F)cc2)nnc1SCC(N)=O +Cc1ccc(C(=O)N2CCN(c3ccc(Cl)cn3)CC2)c(=O)[nH]1 +CNc1nc(CNC(=O)Nc2ccc(F)cc2OC(F)F)cs1 +Cc1cc(C)c(NC(=O)c2ccc3c(c2)OCCO3)c(C)c1 +CCN(Cc1csc(NC(C)=O)n1)c1ccccc1 +CCC(C)(C)NC(=O)c1cccc(NS(C)(=O)=O)c1 +CC(C)(C(=O)Nc1ccc2c(c1)C(=O)NCC2)c1cccc(F)c1 +Cc1noc(C)c1CN1C(=O)CNc2cc(F)c(F)cc21 +CCCc1cc(N2CCCC(O)CC2)n2nccc2n1 +N#Cc1ccc(N2CCC(NC(=O)NCc3ccncc3)CC2)nc1 +CCc1nc2ccccc2n1CC(O)c1c(F)cccc1F +CC(C)Oc1ccc(C(=O)NCCCn2ncccc2=O)cc1 +CCC(C)NC(=O)C1CCN(c2ccc(F)c(F)c2)C1=O +N#Cc1ccc(CNc2cccc3cccnc23)cc1 +CCOC(=O)c1ccn(-c2cccc(NC(=O)NC(C)CO)c2)n1 +CNS(=O)(=O)CCn1ccnc1-c1ccccc1Cn1cccn1 +CCOC(=O)C1CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +Cn1cc2c3c(cccc31)CN(C(=O)c1c(F)cccc1F)CC2 +O=C(Cn1ccnc1-c1cccs1)NCc1ccccc1F +COCCC1(CNC(=O)c2cnn(-c3ccncc3)c2C)CC1 +O=C1COc2ccc(C(=O)COC(=O)c3ccc(F)cc3)cc2N1 +Cc1ccc(C)c(C(=O)NCCOc2ccc3c(c2)CCC(=O)N3)c1 +CCCC1CN(C(=O)c2cc(F)ccc2NC(=O)C2CC2C)CCO1 +CC(C)(CNC(=O)c1ccccn1)c1cccc(Cl)c1 +COc1ccc(C2Nn3c(nnc3-c3ccccc3)S2)cc1OC +COc1cc(S(=O)(=O)NC2CC2)cc(N)c1OC +CCNC(=O)CNC(=O)Cc1nc2nc(C)cc(C)n2n1 +Cc1ccc2ncc(C(=O)Nc3cnccc3OC(C)(C)C)n2c1 +CC1CCCC(CCn2c(=O)oc3cccnc32)C1 +CN(C)C(=O)c1ccc2ccc(N3CCOCC3)n2c1 +COCC(=O)N1CCCC(C(=O)NCCn2cccc2)C1 +NC(=O)Cn1c(N)nnc1SCCc1ccccc1 +CCOC(=O)Nc1ccc(C(=O)NCC2CCC2)cc1 +O=C(Nc1ccc2oc(C(F)(F)F)cc(=O)c2c1)C1CCCO1 +CC(Oc1cccc(Br)c1)C(=O)Nc1ccon1 +O=C(Nc1cccc2cccnc12)c1cc2c([nH]c1=O)CCCC2 +Cc1oc(NC(=O)C(C)N2CCc3cc(F)ccc3C2)c(C#N)c1C +Cc1noc(CCC(=O)NC(C)c2ccc(OC(F)F)cc2)n1 +CCS(=O)(=O)c1ccc(O)c(NC(=O)c2ccc[nH]c2=O)c1 +CC(=O)c1cccc(NC(=O)C(C)Sc2nnc(C)s2)c1 +O=C(Cn1cnnn1)NC(c1ccc(F)cc1F)C1CCCC1 +COC(=O)c1cc(C(=O)Nc2nncs2)n(-c2ccccc2)n1 +COC(=O)c1cnc(SCC(=O)c2ccc(Cl)cc2)n1C +O=C(NCc1ccco1)c1cnc2sc(N3CCCC3)nn2c1=O +Cc1ncccc1C(=O)NC1CC(=O)N(Cc2cccc(F)c2)C1 +CCCN(C)C(=O)NC1CCN(S(=O)(=O)C2CC2)CC1 +CC(=O)N1CC2CCC(C1)N(C(=O)Cn1ccc(=O)[nH]c1=O)C2 +Cc1nc(N2CCCC2)ncc1C(=O)NCc1ccc(F)cc1 +CCCn1cc(NC(=O)c2ccc3c(c2)OCCCO3)ccc1=O +Cc1cc(C2CCCN(C(=O)CCCc3nc(C4CC4)no3)C2)n[nH]1 +CCOC(=O)c1nn(CC(C)C)c2c1CN(Cc1cn[nH]c1)CC2 +O=c1oc2ccccc2n1Cc1noc(-c2cccc(F)c2)n1 +CCN(C(=O)c1ccccc1NC(=O)C1CC1)c1ccccc1 +Cc1nccn1-c1ncccc1NC(=O)c1ccc2c(c1)CCC(=O)N2 +CCN(Cc1cnn(C)c1)C(=O)c1[nH]c(C)c(C(=O)OC(C)C)c1C +CCOc1cc(CO)ccc1OCC(=O)Nc1ccccc1 +O=C1CCCCN1c1ccc(S(=O)(=O)NC2CCCC2)cc1 +Cc1nc(CNC(=O)CCCc2c[nH]c3ccccc23)no1 +CC(NC(=O)C1Cc2ccccc2CN1)c1cccs1 +O=C(c1cc(-c2ccccc2)nc2ncccc12)N1CCCC1 +Cc1ccn2c(=NC(=O)c3cc(Cl)c4c(c3)OCO4)[nH]nc2c1 +CN1CCN(C(=O)Cc2cccc3ccccc23)CC1 +CCc1ccc(Cl)c(CC)c1NC(=O)NCc1ccnn1C +CC(C)(C)n1cc(NS(=O)(=O)c2cc(F)cc(F)c2)cn1 +CC(CNc1ncnc2sccc12)CN1CCCC1=O +CCCCN(C)C(=O)c1c[nH]c2ccccc2c1=O +OC(CN1CCOCC1C1CC1)c1ccc(Cl)cc1 +COc1ccccc1OC(C)C(=O)Nc1nonc1-c1cccs1 +O=C(NCc1ccc(Cl)cc1)C1CCCc2[nH]ncc21 +O=C(Nc1ccc(-c2nccs2)cc1)c1ccc(-n2cncn2)cc1 +Cc1ncc(C(=O)NCC#Cc2cccc(C(F)(F)F)c2)s1 +Cc1cccc(NC(=O)C(C)NC(=O)c2ccccc2C)c1 +Cc1ccc(-c2n[nH]c(C(N)c3ccc(F)cc3)n2)cc1 +COc1ccc(C2CCCN2Cc2n[nH]c(=O)[nH]2)cc1OC +C#CCN1CCN(C(=O)NC(C)Cc2ccccc2F)CC1 +CC(C)C(C)NC(=O)Cc1cc(Cl)c2c(c1)OCCO2 +COCCCn1c(SCC(=O)N2CCC(C)CC2)n[nH]c1=O +Cc1nc2ccccc2n1CCC(=O)N1CCCn2cncc2C1 +CC(CO)Nc1ccc(C(=O)N2CCC(Cn3cccn3)CC2)cn1 +CCc1nnc(CN2CCCC3(C2)OCCO3)n1C +CCNc1cc(F)ccc1C(=O)NC(C)C(=O)OC +COC(=O)c1cc(COc2ccccc2C(N)=O)c(C)s1 +COCCn1ccc2ccc(C(=O)N3CCc4ccccc4C3)cc21 +CC(=O)Nc1ccc(O)c(C(=O)Nc2ccc(C)c(F)c2)c1 +CNC(=O)c1nsc(C(=O)N2CCCC2)c1N +N#Cc1cc(-c2ccc(S(=O)(=O)N3CCCC3)cc2)ccc1O +Cc1cc(C)n(CC(=O)N2CCN(Cc3c(C)noc3C)CC2)n1 +Cc1nnc2c3cnn(-c4cccc(Cl)c4)c3ncn12 +COc1cccc(C(=O)NCCNc2ccc(N)cn2)c1 +Cc1cc(NC(=O)N2CCCC2c2nnc3n2CCCCC3)no1 +C=CCn1c(SC(C)c2nc(CC)no2)nnc1C1CC1 +Cc1ccccc1OCC(=O)Nc1cccn(Cc2ccccc2)c1=O +CC(CN1CCOCC1)NC(=O)c1cc2c(s1)CCCC2 +Cc1ccc2c(c1)C(NC(=O)Nc1ccc3c(c1)COC3)CO2 +CCC(C)C(=O)NCc1ccccc1OCC(F)(F)F +COc1ccccc1NC(=O)c1c(C)nc2ccc(N)cn12 +Cc1csc(C(=O)NC(C)c2ccc(-n3cncn3)cc2)n1 +COc1ccc(C(=O)C2COCCO2)cc1Cl +O=S1(=O)CC(N2CCC3(CC2)OCCO3)c2ccccc21 +CCOC(=O)c1ccc(NC(=O)C23CCC(C2)C(C)(C)C3=O)cc1 +COC1CCCC1OC(=O)c1cc2cc(C)ccc2nc1C +CCCCS(=O)(=O)Nc1ccc(NC(C)=O)cc1 +CCCC1CN(C(=O)C2CN(Cc3ccccc3)CCO2)CCO1 +CCOC(=O)N1CCN(c2c(F)c(F)nc(F)c2F)CC1 +COc1ccc2c(ccn2CCNC(=O)CCc2c(C)noc2C)c1 +CN1C(=O)C2(c3ccccc31)C1(C#N)C(=O)N=C(N)C12C#N +Cc1nc2ccccc2c(=O)n1CCc1ccccc1 +COCCN1C(=O)CCC2C1CCN2C(=O)c1ccoc1 +CCC(NC(=O)N1CCC(C(N)=O)CC1)c1ccc(OC)cc1 +COc1ccc(C(=O)OCC(=O)c2cccs2)cc1N +CC(NC(=O)N(C)Cc1ccccc1)c1nc2ccccc2[nH]1 +CCc1cc(-c2cn3c(N)csc3n2)ccc1OC +Cc1ccc(C)c(C(=O)NCc2cccc(O)c2)c1 +CN(C(=O)NCCc1nccn1Cc1ccccc1)C1CCC1 +C=CCn1c(SCC)nc2c1c(=O)n(C)c(=O)n2C +COc1ccc2nnc(CCC(=O)N=c3[nH]c4ccccc4[nH]3)n2n1 +COc1ccc(CNC(=O)Nc2ccncc2F)cc1F +Cc1cccc(C(=O)N2CCN(c3ccc(O)cc3)CC2)c1C +CC(=O)c1ccc(OCC(=O)c2cc(C)n(C3CC3)c2C)cc1F +CC(=O)c1oc2ccccc2c1NC(=O)Cc1ccccc1 +CN(Cc1ccccn1)C(=O)Nc1ccccc1OCC1CC1 +OCc1cn(CCOc2ccc(Cl)cc2Br)nn1 +CCc1ccc(C(=O)N(C)Cc2ccc3c(c2)OCO3)cc1 +Cc1ccc(-c2nnc(SC(C)C(=O)N(C)CCC#N)o2)cc1 +COCC(C)OC(=O)c1ccc(-n2nc(C)c(Cl)c2C)cc1 +CNC(=O)c1cccc(-c2ccccc2N(C)C)n1 +CCS(=O)(=O)N(C)c1ccc(C(=O)NC(C)COC)cc1 +CC(C)(C)OC(=O)NCCC1CNc2ccccc21 +COc1cc(C#N)ccc1OCCn1cc(Cl)c(=O)[nH]c1=O +O=C(c1ccncc1F)N(CCc1ccc(Cl)cc1)CC1CC1 +O=C(NCCN1CCN(C(=O)CC2CCCC2)CC1)c1cccs1 +CC1CC1c1ccc(CCC(=O)NCc2nnc3n2CCC3)o1 +COc1ccnc(NC(=O)c2ncoc2-c2ccccc2Cl)c1 +COc1c(NC(=O)CCSc2ccc(C)c(C)c2)c(C)nn1C +CCCn1c(C)c(CC(=O)NCC2CC2)c2c1CC(C)(C)CC2=O +Cc1cc(COC(=O)c2ccc(-n3nc(C)cc3C)nc2)on1 +COc1c(F)ccc(C(=O)N2Cc3cnc(CC(C)C)nc3C2)c1F +Cc1ccc(OCC#CCNC(=O)c2c[nH]c3ccccc23)cn1 +Cc1ccc(C)c(C(=O)CCCC(=O)NC(C)C)c1 +Nc1ccc2oc(C(=O)Nc3ccccc3)cc(=O)c2c1 +COc1cccc(C(CNC(=O)c2cccc(N(C)C)c2)OC)c1 +Cc1cc(C(=O)N(CC(C)C)CC(C)C)ccc1N +CNS(=O)(=O)c1ccc(NC(=O)c2ccco2)cc1 +COc1cc(NCc2ccc(S(C)=O)cc2)cc(OC)c1 +COC(=O)c1cccc(S(=O)(=O)N(CC(C)O)c2ccccc2)c1 +CCCCn1ncc(-c2ccccc2)c(CC#N)c1=O +C=CCNC(=O)C(c1ccccc1)c1ccccc1 +CCN(C(=O)Cn1nnc(-c2ccccc2)n1)c1ccccc1 +CC(CO)NC(=O)c1ccc(S(C)(=O)=O)cc1 +CCCc1nc(C(=O)N(C)Cc2cccc(-n3cccn3)c2)cs1 +Cn1cnc2cc(OS(=O)(=O)c3cccc4cccnc34)ccc21 +CCCCN(C)C(=O)Cn1c(-c2ccc(N)cc2)csc1=O +CCN(CC)C(=O)CN1CCN(C(=O)CO)CC1 +CN1Cc2cncn2CC(COCC(=O)N2CCCC2)C1 +Cc1ccc(-n2ccc3c(cnc4ncnn43)c2=O)c(C)c1 +CCn1cc(C(=O)NC2CCCC2)c(=O)c2c(N)cccc21 +CC(=O)c1cccc(NC(=O)C(C)Oc2ccc(C)cc2)c1 +CS(=O)(=O)c1ccc(N)c(S(N)(=O)=O)c1 +O=C1CCc2cc(-c3csc(-c4cnccn4)n3)ccc2N1 +N#Cc1cc2c(=O)n(CCc3cccc4ccccc34)ccc2[nH]c1=O +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)N(C)Cc1cccc(F)c1 +CN(CCc1ccccn1)C(=O)CNC(=O)C(C)(C)C +CC(C)NC(=O)c1[nH]cnc1C(=O)NCc1ccc(F)cc1F +Cc1nnc(NCCc2ccccn2)c(C#N)c1C +CC(=O)c1ccc(S(=O)(=O)N(C)C(=O)c2ccccc2F)cc1 +CCCCn1c(N)c(N(C)CC(=O)N(C)C)c(=O)[nH]c1=O +N#Cc1ccc(OCc2ccc(C(=O)OCc3ccccn3)o2)cc1 +CCNC(=O)COc1ccc(NC(=O)CC)cc1 +CC1CCCCC1OCCNC(=O)c1cnc2c(cnn2C(C)C)c1 +Cc1ccc(CN(C)C(=O)CNC(=O)c2cccc(Cl)c2)s1 +COC(=O)C(C)N(C1CC1)S(=O)(=O)c1cccc2cc(C)cnc12 +CC(=O)N1CCN(c2cnc3ccccc3c2)CC1 +Nc1ccccc1C(=O)Nc1ccc2c(c1)CCC2 +COc1cc(CNc2ccccc2-n2ccc(C)n2)cc2c1OCO2 +CC(Cn1ccnc1-c1nc2ccccc2[nH]1)Oc1cccnc1 +O=C(NCCc1ccccc1Cl)NCCc1nccn1C(F)F +COC(=O)C(CO)NC(=O)c1csc2ccccc12 +Clc1ccccc1Cc1nc(-c2cccnn2)no1 +CCN(CCC#N)C(=O)c1cccc(OCC(F)F)n1 +COC(=O)c1cccc(S(=O)(=O)N(C)CC(F)F)c1C +CC(=O)c1ccc(C(=O)N2CCc3ccccc3C2)s1 +Cn1cc(CC2C(O)CCN2S(=O)(=O)Cc2ccccc2)cn1 +O=C1CCCN1c1ccc(Cl)c(C(=O)N2CCOCC2C2CC2)c1 +O=C(Nc1ccc(S(=O)(=O)N2CCCC2)cc1)c1cnccn1 +COC(=O)c1cc(-c2ccc(OC)c3ccccc23)nn1CCO +CC1(C)Cc2ccc(C(=O)N3CCCCC3)c(O)c2O1 +COc1ccc(OC)c(CNc2cccc(-n3nnnc3C)c2)c1 +CCOc1ccc(NC(=O)N(C)C(C)c2ccccn2)cc1F +CCNC(=O)CN1CCN(C(=O)c2ccc(Cl)cc2F)CC1 +COc1ccc(CCC(=O)N2CCC(N3CCCC3=O)CC2)cc1F +COc1cccc(Nc2nnc(SCC(=O)NC3CC3)s2)c1 +O=C(CCn1c(=O)oc2ccccc21)NC1CCCc2ccccc21 +CC1CCCCC1NC(=O)c1ccc(OCC(F)(F)F)nc1 +C=C(C)CN1CCN(S(=O)(=O)c2ccc(C(=O)OCC)o2)CC1 +Cc1noc(C)c1CCC(=O)NCCn1ccc2c(Cl)cccc21 +Cc1noc(C)c1CNC(=O)N1CCC(OCC2CC2)CC1 +NC(=O)C1CN(C(=O)NCC2CCN(c3ccccc3)C2)CCO1 +c1ccc(-n2cnnc2SCc2cccc3cccnc23)cc1 +Cc1cc(C)nc(N2CCN(C)C(C(=O)N(C)C)C2)n1 +Cc1n[nH]c(C(=O)N2CC3CC4CC(C3)CC2C4)c1Br +Fc1ccc(C2NCCc3ccc4c(c32)OCCO4)cn1 +Cc1cc(C(C)NC(=O)NCc2cccc(C(F)(F)F)c2)c(C)o1 +CC(C)(C)C(=O)CNC(=O)c1cc(Cl)cc(Cl)c1 +COc1cccc(-c2ccc3nc[nH]c(=O)c3c2)c1 +COC(=O)c1ccc(C(=O)Nc2cc(C)ccc2F)cn1 +CC(=O)c1ccc(NC(=O)Cn2cnc3c(C)cccc3c2=O)cc1C +CCC(C)NC(=O)Cc1csc2nc(-c3ccccc3)cn12 +CC(C)Nc1ncnc(Nc2ccccc2F)c1N +COc1ccc(CNC(=O)c2oc3c(c2C)C(=O)CC(C)(C)C3)cc1 +CCC(CCO)NC(=O)Nc1cc(NC(=O)C(C)(C)C)ccc1C +NC(=O)CN(C(=O)C1CCCN(c2ncccn2)C1)C1CCCC1 +NS(=O)(=O)Nc1cnn(CC(=O)NC2CCCC2)c1 +O=C(NCCOc1ncccc1Cl)Nc1ccc2c(c1)COC2 +O=C(c1cccnc1)N1CCc2ncnc(C3CC3)c2CC1 +Cc1ccccc1CNC(=O)c1ccc(S(N)(=O)=O)cc1 +O=C(CNC(=O)c1c[nH]c2ccccc12)NCc1cccs1 +CCOC(=O)c1c(C)n(CC(=O)OC)c2ccc(OC)cc12 +CCc1noc(C)c1C(=O)N1CCn2nc(C(=O)NCCO)cc2C1 +Cc1cccc2[nH]c(CNC(=O)NCCOC(C)C)nc12 +O=C(NCc1ccccc1-n1ccnc1)NC1CC1 +CCc1ccc(OCCCOc2c(C)[nH]ccc2=O)cc1 +CC(=O)c1ccc(OCc2cc(C(=O)N3CCCC3)no2)cc1 +CCOC(=O)N1CCN(C(=O)Nc2cccc(-n3cccn3)c2)CC1 +CCn1c(SCC2CCOC2)nc2ccc(F)cc2c1=O +COc1ccccc1N1CCN(C(=O)c2ccc(C)c(N)c2)CC1 +CC1CCCN(C(=O)CN2CCOCC2C2CC2)C1 +CCC(Cn1c(=O)oc2ccccc21)NC(=O)Cc1ccsc1 +COC(=O)CNC(=O)c1ccc(NC(=O)c2cccc(C)c2C)cc1 +CCCCC(=O)NCC#Cc1ccc(C(C)=O)cc1 +Cc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)s1 +CC(=O)N1CCN(C(=O)C(C)Oc2ccc(-c3nnco3)cc2)CC1 +CCN(Cc1cnc2ccccn12)C(=O)c1cc(C)cs1 +COc1ncccc1CNC(=O)c1ccc(Cl)cc1O +CC1CN(c2ccc(NC(=O)c3cnccn3)cn2)CC(C)O1 +O=C(NC1(c2ccc(F)cc2)CCC1)c1cnc2ccccn2c1=O +Cc1ccc2cc(C#N)c(NCCNC(=O)C3CC3)nc2c1C +COc1ccc2oc(=O)c(-c3nc(-c4nonc4N)no3)cc2c1 +FC(F)Oc1ccc(-c2nnc(SCc3cccnc3)o2)cc1 +Nc1cc(Cl)ccc1C(=O)OCC(=O)N1CCCCCC1 +CCn1cc(C(=O)N2CCN(Cc3cccc(C)c3)CC2)cn1 +Cc1nc(-c2ccc(NC(=O)C3CC3)cc2Cl)n[nH]1 +CCS(=O)(=O)N1Cc2nnn(C)c2C(COC)C1 +CCc1ccc(C(=O)N2CCc3cc(F)ccc3C2)o1 +O=C(CCC(=O)Nc1cccc(F)c1)Nc1cccc(F)c1 +COc1cc(C)sc1C(=O)Nc1ccc2ncccc2c1 +CC(C)C1N=C(O)N(CCc2c[nH]c3ccccc23)C1=O +COC(=O)c1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 +CC(=O)Nc1ccc(F)c(C(=O)OCC2CCCCO2)c1 +COc1cccc(-c2nc(NC3CC3)c(C#N)cc2C)c1 +CC(C)(C)CN1CC(NC(=O)NCc2ccco2)CC1=O +O=C(c1cccc2c1OCCO2)N1CCC(Nc2cccnn2)CC1 +CC(=O)NC(C)C(=O)Nc1nnc(-c2ccccc2Cl)s1 +CC(=O)c1c(C)[nH]c(C(=O)N(CC2CCOC2)c2ccccc2)c1C +CC(C)(C)C(O)CN1CCN(C(=O)Cn2nnc3ccccc32)CC1 +CC1CCCC(N(C)C(=O)CSc2nncs2)C1 +NC(=O)C(Cc1ccccc1)NC(=O)c1cn[nH]n1 +CC(C)C(CNC(=O)N1CCC(C(N)=O)CC1)N1CCOCC1 +CNC(=O)c1cccc(CCNC(=O)c2cc(C)n(C3CC3)c2C)c1 +COC(=O)c1sccc1S(=O)(=O)N1CCCC1 +CC(=O)Nc1cccc(OCC#CCNS(=O)(=O)C(C)C)c1 +O=C(C1COCCO1)N1CCc2ccc(O)cc2C1 +COC(=O)C(NC(=O)c1cnc(N(C)C)nc1C)C1CC1 +CN(C)C(=O)c1cnc(N2CCN(CCO)CC2)c(Cl)c1 +CC(=O)NC1Cc2ccc(S(N)(=O)=O)cc2C1 +CS(=O)(=O)NC1CCN(C(=O)Cn2ccc3ccccc32)CC1 +CC1Oc2ccc(NC(=O)CCc3ccco3)cc2NC1=O +CC(C)OCCCNC(=O)C1c2ccccc2Oc2ccccc21 +CC(NC(=O)c1n[nH]c(=O)[nH]1)C(=O)NCc1ccco1 +CC(=O)c1cc(C(=O)Nc2cccc(OC3CCCC3)c2)n(C)c1 +O=C(NCc1nnc2n1CCC2)Nc1cc(F)cc(F)c1 +COc1ccc(C(C)(C)C)cc1C(=O)CNC(=O)C(C)C +N#CC1CC(=O)N(c2cccc(C(F)(F)F)c2)C1 +Cc1c(C)c2c(c(C)c1N)OCC(C)(C)C(=O)N2C +Cc1ccc(F)c(C(=O)N2CC3C4CCC(O4)C3C2)c1F +Cc1ccc(F)cc1NC(=O)COc1ccccc1C#N +Cc1cnc(N2CCC3(CCCN(c4nncs4)C3)C2)nc1 +COC(=O)c1ccnc(NC(=O)C2CC2c2ccccc2C)c1 +CC1(C)CCN(C(=O)C2CCCN(C(=O)Cc3ccccc3)C2)C1 +Cc1csc(=O)n1CCC(=O)N1CCN(Cc2ccco2)CC1 +CN1CC(CCO)C(n2nnc3ccccc32)c2ccccc21 +COC(=O)c1ccccc1Cn1ccnc1-c1ccc(NC(C)=O)cc1 +COc1cccc(CN2CCc3nc4cccnc4cc3C2)c1 +Cc1cncnc1C1CCN(C(=O)c2ccn(C)n2)CC1 +COCCC(=O)Nc1cc(C)nn1-c1cccc(Br)c1 +CCN(Cc1ccc(OC)cc1)C(=O)c1ccccc1OC +O=C(NCc1cscn1)C1CCN(c2ccc(F)c(F)c2)C1=O +O=C(Nc1cccc(C(F)(F)F)c1)C1CCOCC1 +CCCOc1cc(C)ccc1NCc1csc(C)n1 +Cn1c(=O)c2cc(C(=O)NCC3CCCO3)sc2c2ccccc21 +COc1ccc2nc(SCC(=O)Nc3nnc(C)s3)[nH]c2c1 +COc1ccc(NC(=O)C(C#N)Cc2ccccc2)cc1 +O=C(Nc1ccc(N2CCCCC2)cn1)c1cn2cccnc2n1 +Cc1[nH]c2ccccc2c1SCC(=O)N1CCC(C)CC1 +Cc1c(-c2cccc(F)c2)nn(-c2ccccn2)c1N +O=S(=O)(c1cc(-c2nnc(C3CC3)o2)cs1)N1CCCCC1 +Cn1c(SCCO)nc2sc(-c3ccccc3)cc2c1=O +CC1(C)CN(C(=O)c2ccc(NC(=O)c3ccco3)s2)CCO1 +CC(OC(=O)C1CCCCN1C(=O)c1ccco1)c1ccccc1 +Cc1cccc(OCCNC(=O)Cn2nnc(-c3ccccc3)n2)c1 +COC(=O)c1ccccc1S(=O)(=O)Nc1ccc(Cl)cc1F +Cc1ccc(C(=O)N2CCC(c3nc4cccnc4n3C)C2)cc1 +Cc1cc(C(=O)NCc2ccnc(OC3CCC3)c2)[nH]n1 +CC(=O)N1CCN(C(C(=O)NCc2ccccc2)C2CCCC2)CC1 +Cc1ncccc1-c1cc2cccnc2n1CCCNC(=O)C1CC1 +Cn1c(=O)[nH]c(=O)c2c1nc(NCCO)n2Cc1ccc(Cl)cc1 +CC(C)S(=O)(=O)c1ccccc1C(=O)NCCNC(=O)C1CC1 +CN(Cc1ccccc1NC(=O)C1CC1)C(=O)OC(C)(C)C +C=CCc1cc2c(c(OC)c1O)C(c1ccccn1)NCC2 +CCc1nc2cc(C)cnc2n1CCOc1cccc(N)c1 +COc1ccc(C(=O)Nc2c(C)n[nH]c2C)cc1OC1CCCC1 +CN(C)C(CN=C(O)c1cc2ccccc2oc1=O)c1cccs1 +COc1ccc(OC)c(CN(C)C(=O)C(C)(C)C)c1 +CNC(=O)c1ccccc1NC(=O)c1ccc(N)c(C)c1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2nc(C)cs2)c1 +CN(C)S(=O)(=O)N1Cc2ccccc2-c2ccccc21 +Cc1ccc(-c2nnc(C(C)Sc3ncnc4nc[nH]c34)o2)cc1 +O=C(NCCN1CCOCC1)c1cccc2c1CCN2C(=O)C1CC1 +COCCNC(=O)c1ccccc1NC(=O)Cc1cccs1 +CC(=O)c1csc(NC(=O)c2ccc(=O)n(C)c2)n1 +O=S(=O)(NCC1CCCO1)c1ccc(Oc2ccccc2)cc1 +Cc1cc(NC(=O)NC2CCCc3ccccc32)n(C(C)C)n1 +Cc1cccc(NC(=O)CCN2C(=O)C(C)Oc3ccccc32)c1 +Nc1cccc(OCCC(=O)NCc2cccnc2)c1 +CC(C)c1nc(CN2CCN(S(C)(=O)=O)CC2)no1 +CCOC(=O)N1CCN(C(=O)Cc2cccc3ccccc23)CC1 +CCNc1ncnc(N2CCN(c3cccc(C)c3C)CC2)c1N +CCOC1CCCN(S(=O)(=O)c2ccc(F)c(NC(C)=O)c2)C1 +O=C(Nc1ccccc1Cl)c1c[nH]c2c(F)cccc2c1=O +CC1CN(C(=O)NC2CCc3ccc(F)cc32)CC(C)O1 +CCC(=O)N1CCCC1C(=O)c1ccc2c(c1)CCCC2 +O=C(c1cc(C2CC2)on1)N(Cc1ccco1)C1CC1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N(C)c1ccc(F)cc1 +CC(=O)Nc1ccc(NC(=O)NCc2scnc2C)c(Cl)c1 +N#Cc1ccc(C(=O)N2CCC(C(=O)Nc3ccncc3)CC2)cc1 +O=C(NCc1cscn1)c1cc(Br)c[nH]1 +COc1ccccc1N1CCN(CC(=O)Nc2ncccc2C)C1=O +Cc1ccccc1C1=NC(=C2C=CC=CN2C)C(=O)O1 +CC(NC(=O)c1nnn(-c2ccc(F)cc2)c1N)c1ccccc1 +CCCn1cnnc1CNC(=O)CN1CCN(c2ncccn2)CC1 +CNc1snc(C)c1C(=O)NCC1CCOC1 +O=C(Cn1cnc2ccsc2c1=O)N1CCCC1 +CC(=O)C(C)Sc1nnc(NCC(C)C)s1 +CC(=O)N1CCc2cc(-c3cc(C#N)n[nH]3)ccc21 +C#CCOc1ccc(CCNC(=O)C2CC(=O)N(CC)C2)cc1 +CCCCS(=O)(=O)N1CCCC1C(=O)Nc1ccc(Cl)cc1 +Cc1cc(CN2CCN(C(=O)COc3ccccc3O)CC2)on1 +CCOc1cc(C(=O)N(C)CCC(C)C)ccc1OC +CCn1nc(C)c(S(=O)(=O)N=c2[nH]c3c(s2)CCCC3)c1C +CCCC1CCc2c(sc(NC(=O)c3ccco3)c2C(N)=O)C1 +Cc1nc2cc3c(cc2n(CCC#N)c1=O)OCCO3 +N#Cc1cnn(-c2cc(Oc3ccccc3)ncn2)c1N +CCn1c(SCC(=O)OC)nnc1-c1ccccc1OC +NS(=O)(=O)N1CCN(CCN2CCCC2=O)CC1 +CCN(CC1COc2ccccc2O1)C(=O)CCc1ccsc1 +CN(C(=O)c1cncc(F)c1)c1cccc2ncccc12 +CC(NC(=O)NCCNS(C)(=O)=O)c1ccc2c(c1)OCO2 +Cc1cccc(NC(=O)CSc2nc(C)cc(N)n2)c1 +Cc1ccc(Nc2cc(=O)n(C)c(=O)n2C)cc1Cl +N#Cc1cccc(NCC(=O)Nc2ccc(F)c(Cl)c2)c1 +CNC(=O)NCC(=O)NC(C)c1ccc(OC(F)(F)F)cc1 +Cc1cc(NC(=O)COc2ccc(Cl)cc2)no1 +O=C1CCc2cc(NC(=O)NCCCc3ccccc3)ccc2N1 +CS(=O)(=O)c1ccc(NC(=O)c2ccsc2)cc1 +CN(C(=O)C1CC(=O)N(CC(F)(F)F)C1)c1cn[nH]c1 +CCC1Nc2cc(F)c(F)cc2N(CC(N)=O)C1=O +CCCN(CCO)C(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +Nc1ccc(Cn2c(C3CC3)nc3ccc(F)cc32)cn1 +COc1ccc(C(=O)NCc2ncc(C)c(OC)c2C)cc1F +CC(C)Oc1ccccc1NC(=O)c1cccc(F)c1N +O=C(CCCN1CCOC1=O)NCc1ccnc(-n2cccn2)c1 +Cc1ccc(OCCCn2nnc(CO)c2-c2ccco2)cc1 +CC(C)(O)c1nc2ccccc2n1Cc1ccccc1F +CC(C)(C)n1ncc2c1N=C(O)CC2c1cccnc1 +CCCC(=O)NCC(=O)NCC(O)c1c(Cl)cccc1Cl +Cc1ccc(N(C(C)C(=O)N2CCCC(C)C2)S(C)(=O)=O)cc1 +COCCN(Cc1ccc(C)o1)C(=O)Cc1ccc[nH]1 +Nc1nc(C2CC2)ncc1C(=O)NCc1ccccn1 +CC(C)C(=O)Nc1cccc(NC(=O)c2cn[nH]n2)c1 +CNC(=O)c1cc(Cl)ccc1NC(=O)c1cc(C(N)=O)cs1 +O=C(Cc1ccc2c(c1)CCO2)Nc1nc2ccccc2s1 +O=C1CSc2ccccc2N1Cc1nccs1 +Cc1cc(C)n(CC2CCCN2C(=O)C(C)OCC2CCCCO2)n1 +CCNC(=O)C1CCN(S(=O)(=O)c2ccc(OC)cc2)CC1 +CCOC(=O)CN(C(=O)c1ccc(N(C)C)cc1)C(C)C +COc1ccc(N)c2c(C(=O)Nc3ccc(C)cc3)nccc12 +CC(C)CC(NC(=O)Cc1ccc[nH]1)c1ccc(Cl)cc1 +COCCCC(=O)N1CCN(c2nccc(OC)n2)CC1 +CC1(C)CN=C(CNC(=O)CN2CCN(c3ccccc3)C2=O)O1 +CCC(C(=O)N1Cc2nc(C)n(C)c(=O)c2C1)n1cccn1 +CC(C)CC(NS(=O)(=O)N(C)C1CCCCC1)C(=O)N(C)C +CC(C)OCCCNC(=O)Cn1[nH]c(=O)c2ccccc2c1=O +O=C(NC1CCN(c2ncccn2)CC1)c1ccc(-n2ccnc2)nc1 +Cc1noc(C(=O)Nc2cccc(Cl)c2)c1Cl +CC(=O)NCC(=O)NCC1CCN(c2ccccc2)C1 +CC(=O)Nc1cccc(NC(C)C(=O)NCc2ccccc2C)c1C +CCC(=O)N1CCN(c2nc(N)nc3[nH]ncc23)CC(O)C1 +COC(=O)N1CCCCC1NC(=O)OC(C)(C)C +CC1(C)C2CCC1(CS(=O)(=O)N=c1cccc[nH]1)C(=O)C2 +Cc1cccc(-c2nc(CNc3ccc(F)cc3)n[nH]2)c1 +COc1ccc(Nc2nnc(C=Cc3cccs3)c(=O)n2N)cc1 +Cc1ccc(OC(C)C(=O)N2CCCC2c2ccccn2)cc1C +COc1ccc(Cl)cc1NCC(O)c1cccc(N)c1 +CN(C)C(=O)c1cc(C(=O)c2ccc(F)cc2F)c[nH]1 +Cc1ccc(C(=O)N2CCCC(CNC(=O)C(C)C)C2)c(C)c1 +Cc1cc(C(=O)NCC(=O)Nc2ccc(Cl)cc2)on1 +CCNC(=O)N1CCN(C(=O)C2(O)CCCC2)CC1 +O=C(c1ccc(Cn2cnnn2)cc1)N1CCCC1c1ccccc1 +COc1cc(CO)cc(N)c1OCC(O)c1ccc(F)cc1 +CCOCC1CCCN(C(=O)Nc2cc(NC(C)=O)ccc2C)C1 +CN1CCC(NC(=O)CSc2ccccc2)C1=O +Cc1nc(CC(=O)N(C)CC(=O)Nc2cccc(C)c2C)cs1 +O=C(Cc1ccc(F)c(F)c1)Nc1c[nH]cc(Br)c1=O +CC(=O)c1ccccc1OCC(=O)c1ccccc1 +Cc1cnc(NC(=O)c2ccc(N)cc2Cl)s1 +Cc1ncc(C(=O)N(Cc2c(C)nn(C)c2C)C2CC2)c(=O)[nH]1 +CCn1cc(NCc2cccc(OC)c2OC)c(C)n1 +Cc1noc(C)c1S(=O)(=O)N1CCCC1c1cc(C(C)C)on1 +Nc1cccc2c1CN(Cc1ccccc1F)C2=O +Cc1cnc(C(=O)N2CCCCC2C2OCCO2)cn1 +O=C(Cc1csc(-c2ncccn2)n1)OCC1CCCCO1 +Nc1ccc(-c2ccc(Cl)cc2)n(CC2CCCO2)c1=O +Cc1ccc2nc(SCC(=O)Nc3nonc3N)[nH]c2c1 +COC(=O)C1CCN(C(=O)c2cc(C)c(C)s2)c2ccccc21 +NC(=O)CCN(Cc1cc(=O)c(O)co1)c1ccc(F)cc1 +Cc1ccc(C(=O)N2CCC(C(N)=O)CC2)cc1S(C)(=O)=O +CCC(CC)NC(=O)CCNC(=O)c1ccc(F)cc1 +Cc1cc(C)c(C)c(SCC(=O)N2CCCC(C(N)=O)C2)c1C +COc1ccc(-n2ccnc(NCc3cccs3)c2=O)cc1Cl +COc1cc(C(=O)N(C)Cc2ccc(C)o2)on1 +Cc1ncsc1C(=O)Nc1cc(N)c(F)cc1F +Cc1nc2n(CC(=O)c3ccc(Cl)cc3)c3ccccc3n2n1 +Cc1ccc(C(N)=O)cc1NC(=O)N1CCc2ccccc2C1 +COc1ccc(C2CCCCCN2C(=O)Cn2ccnc2)cc1 +NC(=O)c1nc(N2CCCCC2)nc(N2CCCCC2)n1 +O=C(NCc1cc2ccccc2o1)NCC1(CO)CC1 +Cc1ccc(NC(=O)C2CCCN(C(=O)NC3CCCC3)C2)nc1 +CS(=O)(=O)c1cc(C(=O)OCC2CC2)c(Cl)cc1Cl +CCc1ccc(OCC(=O)Nc2ccc(C)cc2)c(-n2cnnc2)c1 +CC(C)C(=O)Nc1cc(C(=O)NC2CCCC2)nn1C +CC(O)CN1CCN(C(=O)C2(C)CCOCC2)CC1 +CCOc1ncccc1C(=O)N(CCC(N)=O)c1ccccc1 +O=C(NCc1ccccn1)c1nc2ccccn2c1-c1ccsc1 +CC(CNC(=O)NC(C)C1CCCO1)Oc1ccccc1 +COc1ccccc1C1(NC(=O)C2CCCO2)CCCC1 +COc1ccc(OC(C)C(=O)N2CCN(c3ccccc3)CC2)cc1 +CSc1nc(N)n2nc(-c3cccs3)cc2n1 +COCCOc1cccc(NCc2ccc(C)s2)c1 +CCOc1ccc(F)c(C(=O)N(C)CC(O)COC)c1F +FC(F)(F)c1ccc(-c2noc3c2CN(Cc2ccoc2)CC3)cc1 +CC(C)CC(C)OCCC(=O)Nc1ccc2c(c1)CC(=O)N2 +Cc1nc2ccc(NC(=O)NCc3cnn(-c4ccccc4)c3)cc2o1 +Cc1nc2ccc(NC(=O)NCCN(C)c3ccccc3)cc2o1 +Cc1[nH]c2ccccc2c1C(=O)Cn1ncc(Cl)c(Cl)c1=O +N#CCCN(CCC#N)C(=O)CSc1nc2ccccc2s1 +Cc1ccn(-c2cc(COC(=O)c3ccn4cncc4c3)ccn2)n1 +CN(C)c1ccc(C(=O)NCc2ccc(CS(N)(=O)=O)cc2)cc1 +COc1ccc(C(O)CNC(=O)c2ccn(C)c(=O)c2)cc1 +C=CCn1nnnc1SC(C)C(=O)N1CCSc2ccccc21 +Cc1nn(-c2ccccc2)c(OC2CCCC2)c1CO +Cc1ccc(C(=O)Nc2ccc3[nH]cc(C#N)c3c2)cc1 +CCCCN(CCOC)C(=O)c1nc2nccc(C)n2n1 +N#Cc1ccc(CNC(=O)c2ccc(Br)cc2)cc1 +Cc1c(C(C)NC(=O)c2csc(-c3ccccc3)n2)cnn1C +CCNc1nnc(SCCC(=O)c2ccc(F)cc2)s1 +Cn1cc(CNC(=O)Nc2ccc(Br)cc2F)cn1 +CCOc1ccc(C(C)NC(=O)CCn2c(C)csc2=O)cc1 +Cc1n[nH]c(SCCC(=O)N2CCc3ccccc32)n1 +Cc1nc(-n2cccc2)sc1C(=O)Nc1cccc2c1ccn2C +Cc1nn(CC(=O)OC(C)C)c(C)c1CN1CC(C)OCC1C +CCCn1cnnc1C1CCN(C(=O)COc2cccc(C)c2)CC1 +Cc1ccc(C)c2c(=O)cc(CNC(C)Cc3cnccn3)[nH]c12 +CC(=O)N(C)c1ccc(NC(=O)c2cccnc2OCC(F)F)cc1 +CC(OC(=O)c1ccc(OC(F)F)cc1)C(N)=O +CCN(CC)C(C(=O)NCc1ncn(C)n1)c1ccccc1 +CCOC(=O)CN(C)Cc1cc(=O)oc2cc(C)c(C(C)C)cc12 +COc1cccc(CCNC(=O)N(C)Cc2ccoc2C)c1 +CC(=O)Nc1cccc(C(=O)Nc2ccc(C(=O)OC(C)C)cc2)c1 +CCc1cc2c(=O)n(Cc3nnnn3-c3ccccc3)cnc2s1 +CCc1nc(-c2cn(Cc3cccc(F)c3)nn2)no1 +CC(C)CN1C(=O)C(C(C)C)Oc2ccc(N)cc21 +CC(C(=O)NCc1cccnc1-n1ccnc1)n1cncn1 +NC(C(=O)OCc1cccs1)C1CCCCC1 +CCOC(=O)N1CCC(NC(=O)COc2cccc(C(C)C)c2)CC1 +Cc1ccc(CNC(=O)c2ccccc2NC(=O)c2cccnc2)cc1 +CCCc1noc(CNc2ccccc2Cl)n1 +CCOC(=O)c1c[nH]c2cc(Cl)c(-c3ccco3)cc2c1=O +COc1ccc(CNS(=O)(=O)c2ccc(OC)c(OC)c2)cc1 +O=C(c1ccc(-n2cccn2)cc1)N1CCN(c2ccc(O)cc2)CC1 +COC(=O)CSc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +Cc1nn(C)c(NC(=O)CCOC(C)CC(C)C)c1C +O=C(CC1CCCC1)Nc1ccn(-c2ncccc2Cl)n1 +O=c1ccc(C2NCCc3c2cc(F)c(F)c3F)n[nH]1 +COc1ccc(C(=O)NCc2ccc(F)cc2)cn1 +CC(=O)Nc1ccc(O)c(C(=O)N2CCOC(c3ccccc3)C2)c1 +Cc1ccc(CSc2nnc(-c3cnccn3)n2C)cc1 +Cc1nn(CC(=O)Oc2cccc(Cl)c2)c(=O)c2ccccc12 +O=C(NCc1ccco1)C1C(c2ccccc2)C1(Cl)Cl +CCOc1ccc(CN(C)C(=O)c2cccnc2O)cc1 +COc1ccc(CC(=O)Nc2ccc(C)cc2F)cc1OC +CC(C)c1nnc(C2CCN(C(=O)c3ccc(F)c(F)c3)CC2)o1 +COC(=O)c1coc(S(=O)(=O)N(C)c2cccc3ncccc23)c1 +Cc1ccc(OC2CCN(C(=O)c3c(C)noc3C)CC2)cc1C +CCCCN(CCCC)C(=O)Nc1cnn(C)c1 +O=C(Cn1ncc(=O)c2ccccc21)Oc1ccc(-n2cnnn2)cc1 +CC(C)OC(=O)CCNC(=O)Nc1cccc(Br)c1 +Cc1ccc(NC(=O)CC2(O)CCCCC2)cc1S(C)(=O)=O +O=C1C(=O)N(Cc2ccc(Cl)cc2)c2ccc(F)cc21 +CCCc1ccccc1NC(=O)N1CCCC1CN1CCOCC1 +COc1ccccc1OCc1cc(C(=O)NCC2CCCO2)no1 +CC(C)CC(=O)NC(C(=O)Nc1cccc(-c2ccn[nH]2)c1)C(C)C +COc1ccc(NC(=O)c2ccnnc2)c(Cl)c1 +CC(C)n1c(C(=O)NCC(O)c2ccccc2)cc2sccc21 +CC(=O)Nc1ccc(C(=O)Nc2nc(C(C)C)cs2)cc1 +COc1ccc(C(CO)N(C)C(=O)NCc2sccc2C)cc1 +Cc1cccc(NC(=O)c2cc(S(C)(=O)=O)ccc2Cl)n1 +Cc1ccc(Cl)c(NC(=O)c2cn[nH]c2)c1Cl +COc1ccc(Nc2nc3c(c(=O)[nH]2)CCC3)cc1F +Cn1cc(C(N)=O)cc1C(=O)Nc1ccc(N2CCCC2=O)cc1 +CC(C)(O)CCc1cccc(C(=O)N2CC(N3CCOCC3)C2)c1 +Cc1csc(CN(C)Cc2ccc(F)cc2C)n1 +CC(=O)NC(C(=O)NCc1ccccc1C)C(C)C +CCCc1cc(=O)[nH]c(SCC(=O)c2cc(C)n(C)c2C)n1 +Cc1c[nH]nc1C1CCCN1C(=O)c1c[nH]nc1C +O=C(NCCNC(=O)N1CCc2sccc2C1)c1cccnc1 +O=C(OCC(=O)N1CCCC1)c1cc2ccccc2oc1=O +O=c1ccc2cc(S(=O)(=O)Nc3ccccn3)ccc2o1 +CC1COCCN1C(=O)NCc1cccc(Cn2cccn2)c1 +CCOC(=O)c1c(C)[nH]c(C(=O)NC2(C#N)CCCCC2)c1C +CC(C)c1nc2scc(-c3ccccn3)n2c1N +CCOc1ccc(-c2nnc3ccc(Cl)cn23)cc1N +CC1CN(C(=O)c2ccc(C(N)=O)cc2)c2ccc(F)cc2O1 +CCCN(CC1CC1)C(=O)COc1ncnc2ccccc12 +CC(=O)c1cc(F)c(NC(=O)CC2CCCO2)c(F)c1 +O=C(Nc1ccccc1C(=O)Nc1ccccn1)c1ccsc1 +Cn1nccc1C(=O)NCc1ccc(-c2nc3ccccc3[nH]2)cc1 +Cc1[nH]ncc1S(=O)(=O)NCCC1CCCC1 +Cc1nc(N2CCC(C)CC2)ncc1C(=O)Nc1cccc(F)c1 +CNC(=O)C1Cc2ccccc2N1C(=O)c1cccc(OC)c1 +Cc1cccc(C(=O)N2CCc3[nH]nc(C(=O)N4CCCC4)c3C2)c1 +CC(=O)c1ccc(OS(=O)(=O)c2cccs2)cc1 +CCS(=O)(=O)c1ccc2c(c1)N(Cc1ccccc1)C(=O)CO2 +CC(C)CCOCCC(=O)Nc1ccc(Cl)cc1N +CCc1c(-c2ccncc2)n[nH]c1NC(=O)c1cccc(CC#N)c1 +Cc1cnc(C(=O)NCCC(O)(c2ccc(C)o2)C(F)(F)F)cn1 +COc1ccc(Cl)cc1-c1nc(-c2ccn3cnnc3c2)no1 +CC(=O)c1cccc(NC(=O)CNc2ccc(F)c(F)c2)c1 +O=C(NCCn1cccc1)C1CCC(=O)N(C2CCCC2)C1 +COc1ccccc1N1CCN(CC(O)CO)CC1 +C=CCN(c1ccc(C(C)=O)cc1)S(=O)(=O)CC +CCCCCNC(=O)NCc1cn(-c2ccccc2)nn1 +O=C(NCc1cc(F)ccc1Br)NC1CC1 +CC(O)CN1CCN(C(=O)CCc2cscn2)CC1 +CC(NC(=O)NC(c1ccco1)C(C)(C)C)C1CCOCC1 +O=C(Nc1cccnc1)N1CCN(Cc2ccccc2)CC1 +CCN(CC(=O)Nc1cc(Cl)ccc1C)C(=O)c1cnccn1 +CCN1CC2(CCC1=O)CCN(C(=O)C1(Cn3cccn3)CC1)CC2 +N#Cc1ccc(C(=O)Nc2ccc(F)c(Cl)c2)c(F)c1 +CC(=O)Nc1ccc(O)c(C(=O)NCC(O)c2ccc(F)cc2)c1 +NC(=O)CCNC(=O)NCC1CCN(c2ccccc2)C1 +O=C(NCC1CCC1)N1CCC(c2nnc3ccccn23)CC1 +O=C(CCSc1nc(C2CC2)n[nH]1)c1ccc(F)cc1 +N#Cc1ccccc1OCC(=O)NCCC1=CCCCC1 +O=C(Nc1ccc2c(c1)OCO2)N1CCC(N2CCCC2=O)CC1 +CN(C(=O)CCC(C)(C)C)C1CCN(c2ccccc2)C1=O +Fc1ccc(CNc2nn3cnnc3c3ccccc23)cc1 +CC(C)c1nc(C2CCCN2c2cnc3cc(F)c(F)cc3n2)no1 +O=C(NCCCc1nc(Cc2ccccc2)no1)c1ccccc1 +COc1ccc(OC)c(S(=O)(=O)NCC(O)C2CCCCC2)c1 +COc1cccc(CNC(=O)c2cc(C3CC3)on2)c1OC +COc1ccc(CCOc2cccc(N)c2)cc1OC +CCn1c(-c2ccccc2C)nnc1S(=O)(=O)C(C)C(N)=O +COc1ccc(F)cc1C(=O)N1CCC(CN2CCOCC2)CC1 +Cc1ccccc1CC(C)NC(=O)CN1CCN(CCO)CC1 +O=S(=O)(c1ccccc1)n1ccc2cc(F)ccc21 +O=C(CCNC(=O)c1ccsc1)NCc1ccc2c(c1)OCO2 +CC(C)(C)C(=O)NCCc1nc(-c2ccc(C#N)cn2)no1 +O=C(CNC(=O)OCc1ccccc1)NCCO +CC(=O)c1c(C)[nH]c(C(=O)CN(C)Cc2ccccc2Cl)c1C +COCC(C)NC(=O)C(NC(=O)c1ccc(F)cc1)C(C)C +CCc1ncc(C(=O)N2CCC3(CCC(=O)N(CC)C3)CC2)cn1 +N#Cc1nc(COc2ccc3c(c2)OCO3)oc1N1CCOCC1 +N#Cc1ncn(CC(=O)Nc2ccccc2S(=O)(=O)C(F)F)n1 +Cc1ccc(C2C(C(=O)NC(C)C)CCC(=O)N2C)cc1 +CC(C)(Oc1ccc(F)cc1)C(=O)Nn1cc(Br)cn1 +N#Cc1ccccc1OCC(=O)N(Cc1ccncc1)C1CC1 +CC(NS(C)(=O)=O)C(=O)NCc1ccc(C#N)cc1 +CC(C)c1nnc(SCC(=O)Nc2ccc(Cl)cc2)n1N +O=C(Cc1ccc2c(c1)OCCO2)Nc1ccc(F)cc1F +Cc1ccc(CC(=O)OCC(=O)Nc2cc(F)cc(F)c2)cc1 +CNC(=O)C(C)NCc1c(C)nc2sc(C)cn12 +Cc1ccc(NC(=O)CN(C)S(C)(=O)=O)cc1Cl +O=C(CCc1ccco1)Nc1cccc(C(=O)C2CC2)c1 +Cc1ccccc1NC(=O)CSc1nncn1N +CCC(C)C(=O)Nc1cc(C(=O)NCCOC)ccc1Cl +Cc1cc(C)n(CC(=O)NCc2ccc3c(c2)OCCO3)n1 +CC(C)c1ccc(C(=O)Nc2ccccc2)c(N)n1 +Cc1cccc(N2CC(C(=O)NCc3ccccn3)CC2=O)c1C +COCC(C)NC(=O)c1ccc(-c2nc3ccccc3s2)o1 +CCNC(=O)c1ccc(CNC(=O)C(NC(N)=O)C(C)C)cc1 +O=C1CC2(CCN(C(=O)C3CC3)CC2)Oc2ccccc21 +Cc1ccc(NC(=O)C(C)NC(=O)c2ccco2)cc1F +CN(CC(=O)NCc1ccco1)C(=O)CCc1c[nH]c2ccccc12 +CCOc1ccc2nc(SCC(=O)NC3(C#N)CCCC3)[nH]c2c1 +COc1ccccc1NC(=O)Cn1ncc(Cl)c(Cl)c1=O +N#CC(C(=O)c1ccc(Cl)cc1)c1nnc2n1CCCCC2 +COc1ccccc1NC(=O)CSc1nccn1C +N#CCCCCN1CCN(C(=O)c2ccccc2)CC1 +COc1cc(F)ccc1NC(=O)CCNC(=O)c1ccco1 +Nc1ccc2nc(SCC(=O)c3ccc4c(c3)OCO4)sc2c1 +Cc1c(C(=O)N(C)CC2COc3ccccc3O2)cnn1C +Cc1ccc(N2CCN(Cc3ccc(F)c(F)c3)C(CCO)C2)nn1 +COCc1cc(CNC(=O)c2cc(C(C)C)nn2C)n[nH]1 +Cc1nnc2n1C(C)CN(C(=O)CCn1cncn1)C2 +COC(=O)NC(C)C(=O)Nc1cc(Cl)ccn1 +O=C(c1ccccc1)N1CC(c2nc(-c3cccs3)no2)C1 +NS(=O)(=O)c1cccc(NC(=O)c2cc3ccccc3o2)c1 +CCNC(=O)NCc1ccc(NC(=O)Cc2cc(F)ccc2F)cc1 +CCC(C)NC(=O)C1CC(C)N(Cc2nc(C)no2)c2ccccc21 +CC(C)(C)C(=O)Nc1ccc2[nH]c(=O)sc2c1 +COCCC1COC2(CCCN(C(=O)Cc3cccs3)C2)C1 +COc1ccc(S(=O)(=O)N2CCN(C)C(c3ccccc3)C2)cc1 +CC(C)(C)C(=O)NCc1nc(-c2cccs2)no1 +O=C(Cc1cccc(F)c1)NCC(=O)N1CCN(CCO)CC1 +CCOC(=O)CCNC(=O)N1CCCC1c1cc(C(C)C)on1 +COc1cccc(-c2cc(C(=O)NCCN3CCOCC3)[nH]n2)c1 +CC1CN(CC(=O)N(C)CCC#N)c2ccc(F)cc2N1 +CN(C)c1ccc2nc(-c3cc(N)[nH]n3)sc2c1 +CC(C)NC(=O)c1ccc2nc(-c3ccccc3)cn2c1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(-c3ccc(C)s3)n[nH]2)c1C +COC(=O)Cc1ccc(OCc2ccccc2C#N)cc1 +COc1cc2c(cc1OC)CCN(C(=O)C1(C#N)CCCCC1)CC2 +Cc1ccc2[nH]nc(C(=O)N3CCN(CCc4ccccc4)CC3)c2c1 +O=C(Cc1cccc(F)c1F)NCc1ncc[nH]1 +Cc1nc2c(c(-n3nc(N)c(C#N)n3)nn2C)c(C)c1Cl +COC1CCN(C(=O)c2ccc(C)cn2)CC1Cc1cccc(C)c1 +Cc1c(NCc2cccc(OCC(C)C)c2)cnn1C +COc1cc(CC(=O)NCC2(C(N)=O)CCOCC2)ccc1C +Cc1ccc(N2CCC3(CCN(C)C3=O)CC2)nn1 +COc1ccc2c(c1)-c1onc(C(=O)NC3CC3)c1CC2 +NC(=O)c1ccccc1NS(=O)(=O)c1ccc(F)cc1F +CN(C(=O)CCCC(C)(C)C)c1ccc(Cl)cn1 +CCCC(=O)Nc1ccc(N2CCC(C(=O)NCC(C)C)CC2)nc1 +O=C(Oc1ccc2c(c1)OCO2)C1CC1c1ccccc1F +CCOC(=O)N1CCN(S(=O)(=O)c2c(C)noc2C)CC1 +CC(C)CN(C(=O)CN1CCN(C(=O)C2CCCO2)CC1)C1CC1 +CCNC(=O)c1ccc(N2Cc3cnc(C(C)(C)C)nc3C2)nc1 +CC(C)c1cc(C(=O)N2CCC(C(O)c3ccc(F)cc3)CC2)n[nH]1 +O=C(NCc1cccnc1)c1cn2cc(Cl)ccc2n1 +CCc1cccc(C)c1NC(=O)NCC(=O)OC(C)C +O=C(NCc1cnn2cccnc12)c1csc(Cc2ccccc2)n1 +COc1cc2nc(C3CCC3)n(NC(=O)C(C)C)c(=O)c2cc1OC +CCn1cc(C(=O)N(C)Cc2ccc3c(c2)OCO3)cn1 +O=C(COC(=O)c1cnn(-c2ccccc2)c1)NC1CCCCC1 +Cc1ccccc1CN(C)C(=O)c1cc2c([nH]c1=O)CCCC2 +CNC(=O)C1CCN(C(=O)Nc2ccc(C)c(C)c2)CC1 +CNc1cc(C(=O)NCc2cccc(F)c2)ccn1 +COCc1nnc(NC(=O)c2n[nH]c3c2CCC3)s1 +CS(=O)(=O)N1CCCN(C(=O)c2cn(-c3ccccc3)nn2)CC1 +CC(C)(C)NC(=O)Cc1nc(-c2cnccn2)n[nH]1 +COc1ccccc1C(NC(=O)CC1C=CCC1)c1ccccn1 +COc1ccccc1C(CNC(=O)c1cn(C)nn1)OC +Cc1ncccc1C(=O)NCCCCN1CC(C)OC(C)C1 +Cc1cc2cc(C(=O)NC(C)(CO)CO)oc2cc1C +CCOC(=O)c1ccc(NC2CCCC2OC)nc1 +Cc1ccc(NC(=O)C(C#N)Cc2ccc(O)cc2)cc1 +Cc1noc(C)c1CCC(=O)Nc1ccc2oc(=O)ccc2c1 +COc1ccc(OC)c(C(C)NC(=O)c2ccc(OC)c(OC)c2)c1 +Cc1cnc(CNC(=O)c2cnc3c(c2)CCCC3)cn1 +CC1CCN(C(=O)c2cc(=O)c(OCc3ccccc3)co2)CC1 +O=C(CCNC(=O)c1ccc(F)cc1Cl)NCc1cc[nH]n1 +CCOC(C)c1noc(Cn2nc(CC)nc2CC)n1 +CN(CC(C)(C)O)C(=O)C1CCCN(C(=O)NC2CCCC2)C1 +Cc1csc(NC(=O)NCc2ccnc(OC3CCC3)c2)n1 +CC1CCCC(C)N(C(=O)c2ccnc(OC3CCC3)c2)C1 +COc1ccccc1C(=O)NCC(=O)NC1CCC(O)CC1 +CNC(=O)C1(NC(=O)C2CCCC2)CCCCC1 +Cn1ncc2c(Oc3ccc(Br)cc3F)ncnc21 +O=C(NCCCN1CCOC1=O)C1CCCCCC1 +Cc1ccc(NC(=O)CN2CCc3ccc(N)cc32)cc1 +Cn1cc(S(=O)(=O)NCc2cccc(Cl)c2)c(=O)n(C)c1=O +CCC(=O)N1CCN(Cc2ccc(CC)o2)CC1 +CCC(C)Oc1ccc(NC(=O)Cc2c(C)noc2C)cc1 +O=S(=O)(NCc1cccs1)c1ccc(F)cc1F +COc1cccc(Cn2nnc3cc(C(=O)NC(C)C)ccc32)c1 +CC1CC(C)CN(S(=O)(=O)c2ccc3c(c2)OCCO3)C1 +COc1ccccc1C(C)NC(=O)C(C)Sc1nnc(C)s1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NC1CC(=O)N(C2CC2)C1 +COc1ccc(F)c(NS(=O)(=O)c2ccc(NC(C)=O)cc2)c1 +Cc1cnc(C(=O)Nc2nnc3n2CCCC3)cn1 +Clc1cc(Cl)cc(CNc2cccnc2)c1 +O=c1cc(CNCCCOC2CCCC2)[nH]c2c(Cl)cccc12 +COc1ccc(Cn2nccc2N)cc1Br +CC(=O)Nc1ccc(F)c(NC(=O)c2cnn(-c3ccccc3)c2)c1 +COc1ccccc1OCCN(C)C(=O)c1cccc2ncccc12 +O=C(Nc1cccc(F)c1)C1CCCN1C(=O)OCc1ccccc1 +COc1cc(C(C)=O)ccc1OCCn1c(C)csc1=O +Cc1nnc(SCC(=O)NC2CCCCCC2)n1C(C)C +CCS(=O)(=O)N1CCCC(c2nncn2C2CC2)C1 +Cc1ccc(NC(=O)C2CCN(C(=O)C3(O)CCCC3)CC2)nc1 +COC(=O)c1cc(-c2ccc(SC(C)C)cc2)nn1C +CC(NC(=O)NCc1cscn1)c1ccncc1 +CNS(=O)(=O)c1cccc(C(=O)NCCOc2cccc(C)c2)c1 +O=C(NCc1ccc(Br)cc1)c1ccc2ccccc2n1 +CCCNC(=O)CN(CCC)C(=O)c1cc(Br)cn1C +CC1(C)CC(C(=O)N2CCn3c(C(N)=O)cnc3C2)CCO1 +Cc1n[nH]c(C(=O)NCc2cc(-c3ccccc3)on2)c1Cl +Cc1noc(C)c1CCC(=O)NCc1ccc2c(c1)OCCO2 +Cc1cc(C)n(CC(O)COc2ccc3c(c2)CCC3)n1 +Cc1nc2n(n1)C(CC(=O)Nc1ccc3c(c1)OCO3)C(=O)N2 +COCCNC(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +CNS(=O)(=O)c1ccc(C(=O)Nc2cccc3cnccc23)o1 +COc1cccc(C(=O)NCc2c(F)cccc2OC(F)F)c1F +O=C(OCC(F)F)c1cccc(Oc2cnccn2)c1 +CC(O)c1cn(C2CCN(c3nccc(C(F)(F)F)n3)CC2)nn1 +C=C(C)CN(CC)C(=O)NC(CC)c1ccncc1 +Cc1ccc(S(=O)(=O)N2CCCN(c3ncccn3)CC2)cc1C +O=C(NCC1(O)CCOCC1)c1ccc(F)cc1 +Cc1ccc(C2(O)CCN(Cc3cc(=O)[nH]c(C4CC4)n3)CC2)nc1 +O=C(Cc1nnc(-c2cnccn2)o1)Nc1cccc(Cl)c1F +CC(NCCc1ccco1)c1c(F)cccc1F +CC(=O)Nc1ccc2[nH]c(C(=O)NCc3ccccc3)cc2c1 +COc1cccc(NC(=O)CCc2nc(C)no2)c1 +Cc1nn(C)c(C)c1C(=O)NC(C)c1cccc(F)c1 +O=S(=O)(NCc1ccc(Cl)cc1)c1cccc2nonc12 +CC1CCCN(C(=O)c2nn(-c3ccccc3)c(=O)c3ccccc23)C1 +Cn1c(=O)c2ccccc2n2c(CN3CCOCC3)nnc12 +O=c1cc(C2CCCN(Cc3ccccn3)C2)nc(-c2ccccn2)[nH]1 +O=C(CCNC(=O)c1ccccc1Cl)OC1CCCCC1 +COc1ccc(-c2nnc3ccc(NCCO)nn23)cc1 +Cn1ncc(C(=O)N2CCCc3ccccc32)c1N +CCc1ccc(C(=O)N2CCCC2c2nnc3n2CCCCC3)o1 +Cn1ncc2c1ncn1nc(-c3ccnn3C(F)F)nc21 +CN(C)C(=O)C(Sc1ccc(C(F)(F)F)cn1)c1ccccc1 +CC(C)(C)c1ccc(CCC(=O)N2CCC(C(N)=O)C2)cc1 +CNC(=O)c1cccc(NCC(=O)N2C(C)CCCC2C)c1C +CCc1nc(CC(=O)NCc2ccnc(OC(C)(C)C)c2)cs1 +COC(=O)N(C)CC(=O)N1CCCN(c2ccccc2C#N)CC1 +COc1ccc(S(=O)(=O)Nc2cccnc2)c(C)c1C +Cc1ccc2ncc(C(=O)N(C)c3ccccn3)n2c1 +CCn1c(SCCCNC(C)=O)nc2ccccc21 +Cc1ncsc1C(=O)NCCCOCC1CCCO1 +Cc1cccc(C(=O)OCC(=O)Nc2ccccc2)c1 +COCc1noc(CSc2ncc(-c3ccc(F)cc3)[nH]2)n1 +C=C(C)c1cccc(C(C)(C)NC(=O)Nc2ccc(C(N)=O)cc2)c1 +Cc1nc(C(=O)OC(C)c2nccs2)c(-c2ccccc2)o1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)C1CCOCC1 +CCc1cc(C(=O)NCc2ccc(OC)c(OC)c2)sc1C +Cc1ccc(C2CCCCN2C(=O)NCC(=O)N(C)C)cc1 +O=C(NC(c1ccccc1)C1CCCC1)c1cc[nH]n1 +COC(=O)CN1C(=O)c2sc(C(=O)N(C)C)cc2S1(=O)=O +COCc1ncn2c1CN(C(=O)c1cnc3ccccc3c1)CC2 +CCOCCCNc1nc(-c2ccccc2F)no1 +O=C(NCCCn1ccnc1)c1cc(-c2cccc(Cl)c2)on1 +O=C(c1cnccn1)N1CC2c3ccccc3OCC2(CO)C1 +Cc1cc(N(C)CCO)n2nc(C)c(-c3cccs3)c2n1 +COc1ccc(CCC(=O)N2CCN(CC(C)(C)O)CC2)cc1F +CS(=O)(=O)N1CCN=C1N1CCN(c2cccc(Cl)c2)CC1 +CCCCS(=O)(=O)N1CCN(c2c(C)n[nH]c2C)CC1 +Fc1ccc2c(c1)N(Cc1nnnn1C1CC1)CCC2 +CC(=O)Nc1ccc(C#CCNC(=O)CC(C)(C)C)cc1 +O=c1c2ccccc2ncn1CCOCc1ccccc1 +CCN(CCO)Cc1cc(=O)c2cc(C)ccc2[nH]1 +CC(C)C(C)(C#N)NC(=O)CSc1nnnn1-c1ccc(O)cc1 +COc1cc(C(=O)N(C)CCOc2ccccc2)cc(Cl)c1OC +CN1CCN(C(=O)Cc2ccc(F)cc2)C(c2ccccc2)C1 +Cc1ccc(N2CC(C(=O)N(C)C(C)C)CC2=O)cc1Cl +O=C(Nc1ccc(N2CCCCC2)c2ccncc12)c1ccncc1 +Cc1nnc(SCCCNc2ccnc(C(F)(F)F)n2)s1 +Cc1ocnc1CNc1ccc(Br)cc1C#N +CC(C(=O)N1CCc2ccccc2C1)N1CCCC2(C1)OCCO2 +CC(OC(=O)c1ccc2ccccc2n1)C(=O)N1CCc2ccccc21 +Cc1ccc(-c2nc(C(=O)N(C)C)cs2)c(C)c1 +CC(=O)Nc1ccc(NC(=O)CSc2nnnn2C)cc1 +Cc1nc(-c2c[nH]c(C(=O)NCCN3CCOCC3)c2)cs1 +COC(=O)c1nnn(CC(=O)Nc2c(C)cccc2C)c1C(=O)OC +CCn1c(CNC(=O)C2CCCN2C(=O)C(C)C)nc2ccccc21 +CCCCn1c(S(=O)(=O)C(C)C(=O)NC2CC2)nc(C)c1C +CC(Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)Nc1ccccc1Cl +O=c1c(Cl)c(N2CCc3sccc3C2)cnn1-c1ccccc1 +CCOC(=O)c1cnn(C2CCCN(C(=O)Cc3cc(C)[nH]n3)C2)c1 +N#Cc1cccc(NC(=O)Nc2cccc(OCC3CCCO3)c2)c1 +Cn1cc(CNCC(O)c2ccccc2F)c(-c2cccnc2)n1 +CC(C)CCC(C)NC(=O)C1Cc2ccccc2C(=O)O1 +Oc1ccc(CC2NCCc3cc(F)ccc32)cc1 +CCCS(=O)(=O)N1CCC(NC(=O)c2cnc(C)cn2)CC1 +Cc1nn(CC(=O)NC2CCC(C)CC2)c2ccccc12 +Cn1ccc(C(=O)N2CCN(CCc3ccccc3)CC2)cc1=O +CNC(=O)c1ccc(CNC(=O)Nc2cc(OC)ccc2F)cc1 +CCOC(=O)c1sc2nc(C)nc(N3CCNC(=O)C3)c2c1C +O=C(Nc1ccc2nc(CCCO)[nH]c2c1)c1ccco1 +Cn1cc(S(=O)(=O)N2CC3CCC2C3)c(N)n1 +COC(=O)C1CCN(c2ncnc3ccsc23)CC1 +CCn1c2ccccc2c2cc(NC(=O)N3CCOCC3)ccc21 +CN(C1CCCCCC1)S(=O)(=O)c1cccc(C#N)c1 +CCNC(=O)c1sc2cc(OC)ccc2c1Cl +Cc1ccc(C(=O)Nc2cccc(OCC(N)=O)c2)cc1C +O=C(NCCN1CCOCC1)NC1CCN(c2ccccc2)CC1 +O=C(NCC1CCCO1)c1c(O)cc(F)cc1F +COc1ccc(OC)c(CN(C)C(=O)c2ccc(C)cc2C)c1 +O=C(Nc1ccc(F)cc1OCC(F)(F)F)c1cc(C2CC2)[nH]n1 +CN(Cc1ncnn1C)C(=O)Nc1ccccc1SC1CCCC1 +O=C(NCC1(c2ccc(F)cc2)CCOCC1)NC1CCCC1 +Nc1cccc(S(=O)(=O)Nc2ccc(F)c(Cl)c2)c1 +CN(CC(=O)N1Cc2ccccc2CC1C(N)=O)c1ccccc1 +Cc1cccc(OC(=O)C(C)Oc2ccc(C#N)cc2)c1 +CCOc1ncccc1C(=O)N1CCC(c2ccccc2F)C1 +Cc1cc(=O)oc(C)c1C(=O)NCCC1=CCCCC1 +Cc1nc(NC2CC2)sc1C(=O)NCc1ccccn1 +COC(=O)C(C)(C)NC(=O)c1cnc(-c2ccc3c(c2)OCO3)s1 +Cn1cnnc1C1CCCN(C(=O)c2cccc(Cl)c2Cl)C1 +NC(=O)c1cccc(OC(=O)CCc2ccc(F)cc2)c1 +Cc1cc(C)n2nc(C(=O)Nc3c(C)nn(C)c3C)nc2n1 +CSc1ccc(CNS(=O)(=O)N(C)C)cc1 +CCC(C)(C)NC(=O)Cn1nc(-c2ccc(F)cc2)ccc1=O +COc1ccccc1-n1cc(C(=O)N2CCOC3CCCCC32)cn1 +CCn1c(C)cc(C)c(C(=O)N2CCn3cncc3C2)c1=O +Cc1nnc(NC(=O)CCc2nc(-c3ccncc3)no2)s1 +CCc1nc(C(=O)Nc2cc(C)cc3cccnc23)c[nH]1 +CN(CC(=O)Nc1ccon1)S(=O)(=O)c1ccc(Cl)cc1 +CCC(NS(=O)(=O)c1cccs1)c1cccs1 +Cc1nc(-c2cc(NC(=O)Cc3cccs3)c(C)s2)no1 +CC(CO)C(C)NC(=O)NCc1cc(Cl)c2c(c1)OCCO2 +COCCNC(=O)CN1CCNc2cc(C)c(C)cc21 +Nc1ccccc1NC(=O)CCCn1ccccc1=O +O=C(c1ccccc1Cn1cncn1)N(CCO)Cc1ccccc1 +COCCN1CCN(C(=O)c2cc3c(F)cccc3[nH]2)CC1=O +O=C1NC(c2csc(C3CC3)n2)Nc2c1sc1ccccc21 +CCSc1nnc(C(C)NC(=O)c2ccco2)n1C +Cc1cc(Oc2ccc(F)cc2)ccc1S(N)(=O)=O +CC(C)n1ccc(C(=O)NCc2nc3ccccc3[nH]2)n1 +Cc1ccc(-c2n[nH]c(-c3ccc(O)cc3)n2)cc1N +COc1cc(NC(=O)c2ccc(C)o2)cc(OC)c1 +Cc1ccc(C(=O)NCC(=O)N2CCCc3ccccc32)c(C)n1 +Cn1ccnc1-c1nccn1Cc1ccccc1Cn1cccn1 +COCCNc1nnc(Sc2nc3ccccc3o2)s1 +O=C(NCc1ccccc1)C1CN(C(=O)c2c[nH]c3ccccc23)C1 +O=C1CCCN1c1cccc(OC(=O)C2(c3ccccc3)CC2)c1 +Cc1ccc(C)c(OCCNS(=O)(=O)c2ccc(N)cc2)c1 +CC(C)NC(=O)C(c1ccccc1)N1CCn2c(nnc2C2CC2)C1 +CC1(C(=O)Oc2ccc3c(c2)OCO3)CC1(Cl)Cl +Cn1cnc2c1c(=O)n(Cc1cccc(Cl)c1)c(=O)n2C +CC(=O)c1c[nH]c(C(=O)NCC2(c3ccccc3C)CCOCC2)c1 +Cn1cccc1C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 +Cc1ccc(-c2nc(CC(=O)Nc3cccc4cnccc34)cs2)o1 +CN(C)c1ncc(NC(=O)Nc2ccc(F)cc2F)cn1 +CCOC(=O)c1c(C)nc(N)nc1-c1ccc(OCC)cc1 +NS(=O)(=O)c1cc(C(=O)N2CCCc3ccccc32)cs1 +COc1c(C(=O)OCC(=O)N2CCCc3ccccc32)c(C)nn1C +CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc1ccon1 +CC(C)CCCC(C)NC(=O)N1CCN(C(=O)c2ccco2)CC1 +COc1c(Cl)cc(NC(=O)Cn2cccn2)cc1Cl +CC(C)(C)NC(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +CC(CN1CCOCC1)NC(=O)C1CCCN(c2cnccn2)C1 +C=CCn1c(SCC(=O)N2CCCCC2)nc(N)cc1=O +O=C1CCN(c2cc(-c3ccccc3)nc(-c3cccnc3)n2)CC1 +Cc1nn2cccnc2c1C(=O)NCCc1cn2ccccc2n1 +COc1ccc(NS(=O)(=O)c2ccc(-c3ccc(=O)[nH]n3)o2)cc1 +Cc1noc(C)c1CN1CCC2(COCc3cnc(N(C)C)nc32)C1 +COC(=O)N1CCC(NC(=O)NC(C)c2ccccc2C)CC1 +CCN(CC(C)C)C(=O)CNC(=O)NCc1ccco1 +CCc1noc(CC)c1CNC(=O)c1cc2cc(F)ccc2o1 +CC(Sc1ncn[nH]1)C(=O)NCC(C)c1ccccc1 +COc1ccc(F)c(NC(=O)c2cn(Cc3ccccc3)nn2)c1 +O=C(Nc1ccnc2ccc(Br)cc12)c1ccncc1 +CCOc1ccccc1C(C)NS(=O)(=O)c1cccc2nonc12 +COc1ccc(CC(C)(C#N)N2CCCCC2)cc1OC +O=C(Nc1ccn(Cc2cccnc2)n1)c1ccc(N2CCCC2)nc1 +COc1ccc(CC(C)CN(C)C(=O)NC2CCC(=O)N(C)C2)cc1 +COc1ccc(Cc2nc3ccccc3n2CC(O)CO)cc1OC +Cc1ccccc1OCCCN(C)C(=O)c1ccc2nccnc2c1 +COC(=O)C(C)CN(C(=O)c1ccnnc1)C1CC1 +O=C(Nc1ccc2c(c1)OCCO2)c1cnn(-c2ccccc2)n1 +Cc1ccc(-c2ccsc2C(=O)OCC2CCC(=O)N2)cc1 +Cc1ccc(N2CCN(C(=O)C3(C)CCCO3)CC2=O)cc1 +CC(Oc1ccccc1C=Cc1ccccc1)C(N)=O +CC(C)(CNC(=O)NCc1ccnc2ccccc12)c1ccncc1 +COCCCNC(=O)N1CCn2cccc2C1C +COc1cccc(COC(C)C(=O)N(C)C(C)CC#N)c1 +CN(CCO)c1ncc(Br)c2cc(Cl)ccc12 +COc1ccc2cc(C(=O)NCCc3nc(C)no3)[nH]c2c1 +C#CCCN1CCN(c2nc3ccccc3s2)CC1 +CCOc1ccc(C(F)(F)F)cc1NC(=O)N1CCC(O)CC1 +O=C(NCCCN1CCOCC1)c1csc(-c2ncccn2)n1 +COc1cccc2cc(C(=O)Nc3ccc(Cl)cn3)oc12 +c1nc(N2CCC3(CCCO3)CC2)c2ccsc2n1 +CCn1nc(C)c(Cl)c1C(=O)NCC(=O)NC +COc1ccc(-n2cc(C(=O)n3ccnc3)cn2)cc1 +CC(C)(CNC(=O)Nc1ccncc1)N1CCOCC1 +Cc1csc(N2CCN(C(=O)CCc3ccccn3)CC2)n1 +O=C(COC(=O)c1cccc(NC(=O)C2CC2)c1)NC1CCCCC1 +Cc1nc(SCc2ncon2)c2c(C)c(C)sc2n1 +CC(C)CN(C(=O)NCCN1CCN(c2ncccn2)CC1)C1CC1 +CC(C)(CNS(=O)(=O)c1cc(F)ccc1Cl)c1ccncc1 +CCCC(=O)N1CCCC1C(=O)Oc1ccccc1C +Nc1cn2c(-c3ccc(F)c(Cl)c3)csc2n1 +CC(C)NC(=O)NCc1ccc(C(=O)Nc2ccccc2Cl)cc1 +COCC(=O)N1CCCC(COc2cccc(C)c2)C1 +CS(=O)(=O)N(CC(=O)NC1CC1)Cc1ccccc1 +CN(C)c1nc2ccc(NC(=O)NCc3ncn(C)n3)cc2o1 +Cc1ccc(CN(C)C(=O)c2cc(Br)ccc2O)o1 +Cc1cc(C)c(C(=O)N2CC3CC=CCC3C2)c(=O)[nH]1 +O=C(COc1ccccc1F)NCc1ccncc1 +Cc1ccccc1C1CCCN1S(=O)(=O)N(C)C +CCn1c(SCC(=O)NCc2ccccc2C)nnc1C1CC1 +CCn1nc(C)c(C(=O)N2CCCC(O)(CO)CC2)c1C +Cc1ccc(C#N)c(SCC(=O)c2cccc(Cl)c2)n1 +COc1ccc2nc(C(=O)Nc3cc(F)ccc3F)ccc2c1 +COc1ccc(Cc2nnc(SCC(N)=O)o2)cc1 +COc1ccc(OC)c(-c2ccc(SCc3cccnc3)nn2)c1 +CC(C)OC(NC(=O)c1ccccc1)c1ccccc1 +Cc1cccc(CC(C#N)C(=O)N2CCCCC2)c1 +Cc1ccc2ncc(C(=O)NCc3cnc(C)s3)n2c1 +Cn1cc(S(=O)(=O)NC(c2ccccc2)C2CCCC2)cn1 +COCC(=O)N1CCCCCC1c1ccc(OC)cc1 +COc1ccc(CN(C(=O)c2ccc(C)cc2)C2CC2)cc1 +O=C(c1ccc(Br)cc1F)N1CCCCC1CO +CC1(C)C(=O)C2(C(=O)Nc3ccc4c(c3)OCO4)CCC1C2 +CCc1nc2n(n1)CCCC2NS(=O)(=O)c1ccc(OC)cc1 +CC(C)CC(NC(=O)N1CCOC(CO)C1)c1ccc(Cl)cc1 +CCc1cc(C(=O)N2CCn3cccc3C2C)sc1C +CN(CCNC(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1)c1ccccc1 +CN(CC(=O)Nc1cccc(S(C)(=O)=O)c1)S(C)(=O)=O +COCCCNC(=O)c1ccc(Cl)c(N2CCCC2=O)c1 +CC(=O)c1ccc(S(C)(=O)=O)c(N2CCC(C)(C)C2)c1 +COC(=O)C(NC(=O)c1cccnc1N)C(C)C +CCOc1ccc(S(=O)(=O)N(CC)CC(=O)NC)cc1C +CN(C)C(=O)CCNC(=O)NCc1ccc(C(=O)N(C)C)cc1 +CCOc1cc(NC(=O)CCc2c(C)noc2C)ncn1 +CCc1ccsc1C(=O)NC(C)c1ccc(S(N)(=O)=O)cc1 +Cc1scc(-c2nc(C3CCOC3)no2)c1-c1ccccc1 +COc1ccccc1CC1CCCN1C(=O)c1cnccn1 +CCC(CC)C(=O)N1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +CCCOc1ccc(CNC(=O)c2ccc(=O)[nH]c2)cc1 +CNC(=O)c1ccc(CNC(C)Cc2ccccc2F)cc1 +CN(Cc1nccn1C)c1nncc(-c2ccc3c(c2)OCO3)n1 +Cc1ccc(-c2ncco2)cc1NC(=O)NCc1ccc(C(N)=O)o1 +Fc1ccc(-c2nnn(Cc3cccc(F)c3)n2)cc1 +CCCOc1ccccc1Oc1ncccc1CNC(C)=O +CC(C)C(Cc1ccc(F)cc1)NC(=O)NCC1(O)CCOCC1 +O=C1Nc2cc(Br)ccc2C1NC1CN2CCC1CC2 +CC(C)CNC(=O)N1CCCC(C(=O)N(C)CC2CCC2)C1 +CC(NC(=O)NCC1CC1C)C(=O)NCc1ccco1 +CC(C)CC(NC(=O)C1CCOc2ccccc21)C(=O)OC(C)C +CCOc1ccccc1CC1Oc2ccc(O)cc2NC1=O +CC(=O)c1c(C)[nH]c(C(=O)C(C)Sc2ncc3ccccn23)c1C +Cc1cc(N)cc2c(CC(=O)Nc3ccncc3)noc12 +Cc1nnc(SCC(=O)Nc2ccc(Cl)cc2Cl)n1C +COc1cc(C(=O)NCc2csc(C3CC3)n2)nn1C +CC1=C(c2ccccc2)S(=O)(=O)N=C1N1CCN(C)CC1 +O=C(CCn1cccn1)N1CCCC1c1cccc2ccccc12 +C=CCNc1nnc(Sc2ccc3nnnn3n2)s1 +COc1ccccc1C1CN(c2ncccn2)CCN1C +O=C(COc1ccc(F)c(F)c1)N1CCNCC1 +CC(OC(=O)c1csc2c1CCCC2)C(=O)NC1CCCC1 +Cn1nc(-c2cccs2)cc1C(=O)N1CCc2ccccc2C1 +O=C(CCc1nccs1)N1CCN(c2ncccc2Cl)CC1 +COCC(C)OC(=O)c1sccc1S(=O)(=O)C(F)F +Cc1ccc(NC(=O)c2nnc3ccc(N4CCOCC4)cc3n2)cc1 +Cc1csc(C(C#N)C(=O)C(c2ccccc2)c2ccccc2)n1 +O=C(NC1CCCc2nc(-c3cccnc3)ncc21)c1ccccc1F +CC(=O)Nc1ccc(O)c(C(=O)N(C)C2Cc3ccccc3C2)c1 +COCCN(CCOC)C(=O)c1cccc(Cl)c1 +Cn1c(=O)c(C(=O)NCCc2c[nH]c3ccccc23)cc2cccnc21 +Cc1ccc(C)c(S(=O)(=O)NCCc2n[nH]c(-c3ccco3)n2)c1 +Cc1ccc(C)c(C(=O)Nc2ccc(N3CCCC3=O)cc2)c1 +Cc1cn2c(=O)c(C(=O)Nc3nc(C(C)(C)C)cs3)cnc2s1 +Cn1cc(C(C)(O)CNC(=O)c2cccc(-c3ccoc3)c2)cn1 +O=C(NCc1ccc(OC(F)F)cc1)c1cc(-c2ccccc2)[nH]n1 +CC(C)NC(=O)NCC(C)c1nc(-c2ccccc2)no1 +O=C(OC(c1ccccc1)c1ccncc1)c1ccc2nncn2c1 +Cc1noc(C)c1CCCNC(=O)c1ccc(-c2cccnc2)nc1 +C=C(CS(=O)(=O)c1ccccc1)c1ccccc1 +CCCOC(=O)c1ccc(NC(=O)NCCO)cc1 +CN(C)C(=O)Cn1ccc2cc(NC(=O)NCc3ccon3)ccc21 +COc1cccc(-c2cc(C(=O)NCc3ccccc3Cl)n[nH]2)c1 +O=C(Nc1cnn(CC(F)(F)F)c1)C1COC2C=CC=CC2O1 +COC(=O)C(C)CN(C)c1cnc2cc(F)c(F)cc2n1 +COc1ccnc(NC(=O)CC(NC(C)=O)c2ccc(C)cc2)c1 +CCn1c(SCc2cccc(C#N)c2)nnc1-c1ccncc1 +O=C(NCCc1ccccc1)C1CC(=O)N(Cc2ccco2)C1 +O=C(Nc1ccncc1)N1CCN(C(=O)c2cccc(F)c2)CC1 +CCCCOC(=O)n1ccc(C(=O)Nc2cccc(C)n2)n1 +N#Cc1ccc(S(=O)(=O)Oc2cccc3c2CCC3=O)cc1 +OC(CCNc1ccc(F)cc1)c1cc(F)ccc1F +Cc1cc(-c2nnc3sc(-c4ccccc4Cl)nn23)[nH]n1 +Cc1cc(NCc2cccn2C)ccc1-n1cnnn1 +CN(Cc1ccccc1)C(=O)NCc1nnc2n1CCCCC2 +Cc1ccc(-c2ncc(CN3CCCC(c4nccs4)C3)s2)o1 +COCC(=O)OC(C)c1nc2ccccc2n1C(F)F +CCc1nc2sc3c(n2n1)CCNC3CC(C)C +COc1ccc(-c2nc(CCNC(=O)c3cccc(C#N)c3)co2)cc1 +COc1ccc2ccc(OCc3nnnn3C3CC3)cc2c1 +CC(C)c1nnc(CCC(=O)Nc2cnn(-c3ccccc3F)c2)o1 +CCOc1c(OC)ccc2c1CCNC2c1cncs1 +CCc1cccc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)c1 +COC(=O)c1nc(-n2cccc2)sc1C(=O)c1ccc(OC)cc1 +O=C(NCC1(c2ccc(F)cc2)CCOCC1)c1cccs1 +Cc1nc(CCNC(=O)c2cc(Br)ccc2F)cs1 +CCN(Cc1ccoc1)C(=O)C(C)NC(=O)c1n[nH]c2ccccc12 +CC(Oc1cccc(C(C)C)c1)C(=O)OCC(N)=O +CC(=O)NCCNC(=O)COc1cc(C)ccc1C +COC(=O)c1cc(CN(C)C(=O)c2cnc3[nH]nc(C)c3c2)oc1C +CCC(C)C(NC(N)=O)C(=O)NCc1ccc(C(=O)N(C)C)cc1 +CCN(Cc1ccccc1C#N)c1ccc(C#N)cn1 +COc1ccc(CNC(=O)C(Cc2ccccc2)n2cnnn2)cc1 +CC(C)(C)CCNS(=O)(=O)c1ccc(F)cc1F +CCN(Cc1c(F)cccc1F)Cc1cnnn1C +N#Cc1cccc(Cn2c(N)nc3cc(Cl)ccc32)c1 +CCCN(CCC)C(=O)C1CCN(C(=O)c2cccc(F)c2)CC1 +O=C(CCn1cncn1)Nc1nc(-c2ccccc2)cs1 +COc1cc(COC(=O)c2cnn(-c3ccncc3)c2C)ccc1C +COc1cccc(CNC(=O)Cc2ccc(C)nc2)c1OC +Cc1ccc(NC(=O)Cc2ccccc2C)c(N)c1 +O=c1[nH]c2ccc(S(=O)(=O)Nc3cc(Cl)ccc3O)cc2o1 +Cc1ccc(CNC(=O)NCc2ccccn2)cc1F +O=C(NCC(O)c1ccccc1)c1ccc(-c2ccccc2)[nH]c1=O +CC(=O)Nc1ccccc1NC(=O)c1ccccc1Br +CC(C)COc1ncc(CNC(=O)Cc2ccon2)cc1Cl +O=C(CNc1ccc(F)c(F)c1F)NCc1ccccc1 +O=C(c1ccc2sccc2c1)N1CCN(CCO)CC1 +CCn1ccc2c(cc(C(=O)NCc3cccnc3)n2C)c1=O +CC(C)(CNc1nc2ccccc2c(=O)[nH]1)N1CCOCC1 +CN(CC(F)(F)F)C(=O)C1(c2cccc(F)c2)CCOCC1 +CCOC1CCCN(c2cc(Br)cc(F)c2C(N)=O)C1 +COc1cc(C#N)ccc1OC(C)C(=O)N1CCOCC1 +O=C(Nc1ccc2c(c1)OCO2)c1cn2ccccc2n1 +CCOc1cccc(CNC(=O)CN2CCCC(NC(C)=O)C2)c1 +CCC(OC(=O)c1ccc(N)cc1)C(=O)Nc1ccccc1 +Cc1ccc(-c2csc(NC(=O)c3ccccc3F)n2)o1 +Cc1ccc(NC(=O)NCc2ccco2)c(OCC(F)(F)F)c1 +c1ccc2c(c1)nc(C1CC1)n2Cc1nc(C2CCOC2)n[nH]1 +Cc1ccc(CC(=O)N(C)Cc2ccccc2Br)cn1 +CCN1CC(C(=O)NC(C)c2cccnc2)CC1=O +CC(=O)Nc1nc(-c2nc(C(C)(C)NC(C)=O)no2)cs1 +CC(=O)NCC1CCN(S(=O)(=O)c2cnn(C)c2)CC1 +CC(=O)Nc1ccc(NCC(O)Cn2ccc3ccccc32)cc1 +CN(C(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1)C1CCCCC1 +CC(O)CNc1cccc(CNC(=O)OC(C)(C)C)c1 +CCS(=O)(=O)N1CCCC2(CC(Nc3ncccn3)CO2)C1 +O=C(COc1ccc(Oc2ccccn2)cc1)Nc1ccncc1 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1cc(-c2ccco2)on1 +CC1CCCN(C(=O)Cn2c(=O)n(C)c(=O)c3sccc32)C1 +NC(=O)c1cccc(-c2nc3ccc(F)cc3s2)c1 +CCS(=O)(=O)NCC1CCN(C(=O)c2snnc2C)CC1 +CN(C)C(=O)CC1CNc2cc(N)c(F)cc2N1 +CCOC(=O)CC(C)Sc1nnc(-c2ccccc2C)o1 +CN(C1CCCCC1)S(=O)(=O)c1cccc(N)c1 +COc1ccc(-c2ccc(N)cc2Cl)c(OC)c1OC +COCCCNC(=O)c1nnn(-c2ccc(C)c(F)c2)c1C +Cc1noc(CCCC(=O)NCc2ccc(C(=O)N(C)C)cc2)n1 +COC(=O)CCCN1C(=O)COc2cccc(N)c21 +CCc1ncc(C(=O)N2CC3CCCC3(CO)C2)cn1 +O=c1[nH]c2cc3c(cc2cc1-c1ccc(F)cc1)CCNC3 +COc1ccc(Cn2c(=O)sc3ccccc32)cc1OC +Cc1nc(C)c(-c2ccc(SC(C)C)nn2)s1 +CN(Cc1ccsc1)C(=O)c1ccc(N2CCNC2=O)cc1 +COC(=O)C(C)CNC(=O)Nc1ccc2[nH]ccc2c1 +O=c1c2[nH]c3ccc(Cl)cc3c2ncn1Cc1ccccn1 +Cc1n[nH]cc1CNC(=O)c1ccc(N(C)C)nc1 +CC(Cn1cccn1)NC(=O)c1ccc(N2CCCCCC2)nc1 +N#Cc1cccc(NCC(=O)N2CCCC(C(N)=O)C2)c1 +CNC(=O)c1cccc(CCNC(=O)N2CC(C)OC(C)C2)c1 +COC(=O)c1ccc(C(=O)Nc2cnn(-c3ccccc3F)c2)s1 +CN(C(=O)c1cnc(-c2cnn(C)c2)s1)c1cccc2ncccc12 +Nc1ccc2nc(C(=O)Nc3ccc(Cl)cc3)cn2c1 +COC(=O)c1ccc(Cn2cnc3sc(C)cc3c2=O)cc1F +Cc1noc(CNc2ccccc2S(=O)(=O)NC2CC2)n1 +Cc1ccc(C(=O)NC2CCN(c3ccc(C#N)c(Cl)c3)CC2)o1 +Cc1ccccc1C(O)CNS(=O)(=O)Cc1cccc(C#N)c1 +O=C(c1cccc(F)c1)N1CCOCC(Oc2cnccn2)C1 +Cc1cc(NC(=O)c2ccco2)ccc1NC(=O)Cc1ccccc1 +Cc1cccn2c(=O)c(C(=O)NCc3ccc4c(c3)OCO4)cnc12 +Cc1cnc(C(=O)NCCCN(C)S(C)(=O)=O)cn1 +Cc1cc(C(=O)COC(=O)C2CCCO2)c(C)[nH]1 +Cc1cccc(C)c1OCC(O)Cn1cnc2cc(F)ccc2c1=O +O=C(NCc1cn(-c2ccccc2)nc1-c1ccncc1)C1CCCO1 +COc1ccccc1OC(C)CNC(=O)c1cc(C)n[nH]1 +CCCCc1nnc(NC(=O)c2noc3c2CCCCC3)s1 +CCOC(=O)c1ccc(CNC(=O)c2ccc(C)s2)o1 +Cc1cc(SCC(=O)OCc2ccccc2)nc(=O)[nH]1 +CC(C)(C)C(=O)Nc1cc(C#CCO)ccc1Cl +C=CCn1c(=O)c2c(nc3n(CC(=O)OCC)c(C)cn23)n(C)c1=O +CN(C)C(=O)c1occc1CS(=O)(=O)c1ccccc1 +C=CCn1c(=O)c2c(nc3n(-c4cccc(C)c4)c(C)cn23)n(C)c1=O +O=c1onc(-c2ccccn2)n1Cc1ccc(OC(F)F)cc1 +CC1CCCC(N(C)C(=O)C2(C#N)CCCCC2)C1 +CC(C)(C)Nc1ncc(NC(=O)C2CC2)cc1Cl +O=C(NC(c1ccc(F)cc1)C1CCCO1)c1n[nH]c(=O)[nH]1 +N#Cc1ccc(-c2noc(-c3cccc(C(=O)N4CCCC4)n3)n2)nc1 +CC(=O)c1ccc(C(=O)Nc2ccc3c(c2)CCCN3C(C)=O)cc1 +O=C1CCc2cc(OC(=O)c3ccco3)ccc2N1 +O=C(CCn1cccn1)Nc1nc2ccccc2[nH]1 +Cc1noc(C(C)NC(=O)Nc2cccc(-c3cccs3)c2)n1 +CCC(C)C(NC(N)=O)C(=O)Nc1cccc(C(=O)NC)c1C +CC(c1cncs1)N(C)C(=O)c1nc2ccccn2c1F +Cc1c(C(=O)N2CCCC2Cc2cccc(F)c2)cnn1C +CCOC(C)C(=O)Nc1c(C(N)=O)oc2ccccc12 +N#CCOc1cccc(CC(=O)N2CCc3ccccc3C2)c1 +CC(O)CNC(=O)c1cc(NC(=O)CCc2ccccc2)n(C)n1 +Cc1csc(C(C#N)C(=O)Cc2c[nH]c3ccccc23)n1 +O=C1CC(C(=O)N2CCCC2c2ccccn2)c2ccccc2N1 +CCOCCOc1cc(C)ccc1CNC(=O)C#Cc1ccccc1 +CN(CC(=O)NC(C(N)=O)c1ccccc1)c1ncnc2[nH]cnc12 +O=C(Cc1ccc(F)cc1)N(Cc1cccs1)C1CC1 +CCOc1cccc2nnc(NC(=O)NCC3CCCO3)n12 +NC(=O)NCc1ccc(C(=O)OCC(=O)c2ccc[nH]2)cc1 +O=C(Cn1cc(Br)ccc1=O)N1CCN(C2CC2)CC1 +CC(C)CCOC(=O)CC1C(=O)NCCN1C(=O)c1cccs1 +Cc1ccc(SCCN(C)C(=O)c2ccc(C(C)C)[nH]c2=O)cc1 +O=C(NCCCn1cncn1)NCC1CCCc2ccccc21 +O=C1Nc2ccc(Br)cc2C1NCCc1cccs1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cccc(Cl)c3)cc12 +O=C(NCCc1nnc2n1CCC2)c1cc(=O)[nH]c2ccccc12 +CNC(=O)NC(C)(C)C(=O)Nc1ccccc1F +Cc1ccccc1C(=O)Nc1ccc(CN2CCOC2=O)cc1 +CNC(=O)NC(C)(C)C(=O)NCCCN(C)S(C)(=O)=O +Cc1cc(C)nc(C2CCN(S(=O)(=O)c3cn(C)nc3C)C2)n1 +CNC(=O)c1ccc(Cl)cc1NCC(=O)Nc1ccc(C)cc1 +CCCC(=O)Nc1ccc2c(c1)CN(C(=O)C1CC1)CC2 +CCOC(=O)c1cncnc1-c1ccccc1Cl +CCN(CC)C(=O)C1(NCc2noc(C(C)C)n2)CCCCC1 +CSc1ncc(C(=O)NCC(C)C)n1-c1ccc(F)cc1 +COc1ccc(F)cc1CSc1nc(C)n[nH]1 +O=C1NC(c2ccc(C(F)(F)F)cc2)Nc2ccccc21 +O=C(Cc1csc(-c2ccco2)n1)Nc1ccc(Cl)cn1 +O=C(NCC1(c2ccccc2)CCC1)C1CC(=O)N(C2CC2)C1 +CC(=O)NC(C(=O)N(C)Cc1ccccc1C)C(C)C +O=S(=O)(NCC1=CCCCC1)c1ccc2c(c1)OCCO2 +CN(C)C(=O)c1cccnc1-c1ccc(F)cc1C(F)(F)F +Cc1nc(NC(=O)c2cc(C3CC3)nc3onc(C)c23)sc1C +Nc1ccc(F)c(-c2csc(-c3ccc[nH]3)n2)c1 +COc1cc(F)c(C(O)C2CCCOC2)cc1OC +COc1cccc(C(=O)N(C)Cc2ccccn2)c1O +CCOc1ccc(CN2C(=O)CCS2(=O)=O)cc1 +Cc1ocnc1CNC(=O)Nc1ccn(Cc2ccccc2)n1 +CC(=O)N1CCc2cc(S(=O)(=O)NC(C)C3CCCO3)ccc21 +CC(C)=CC1C(C(=O)Nc2ccn(CC(N)=O)n2)C1(C)C +CCCOC(=O)c1cccc(CS(=O)(=O)c2ccccc2)c1 +O=C(CN1CCN(c2ccccc2)C1=O)N1CCOCC1 +COc1ccc(-c2noc(CCCC(=O)NC(C)(C)C)n2)cc1 +CC(=O)NCC(=O)NCC(=O)NC1CCN(c2ccccc2)CC1 +Cn1cccc1C(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1 +O=C(Nc1ccccc1C(=O)NCCO)c1ccsc1 +O=C(CSc1ccncc1)NC1CCCc2ccccc21 +O=C(Cc1cccnc1)Nc1cncc(Cl)c1Cl +O=C(CN1CCc2ccccc21)NCC(=O)Nc1ccc(F)c(F)c1 +CCn1c(-c2c[nH]c(C(=O)OC)c2)nc2cc(C#N)ccc21 +CCC(CC)C(=O)N1CCN(Cc2cc(=O)c3ccccc3[nH]2)CC1 +CC(=O)N1CCN(S(C)(=O)=O)CC1C(=O)NC1CCCNC1=O +CC(C)n1cc(S(=O)(=O)N2CCOCC2)cn1 +Cc1cc(CCNC(=O)c2cc(-c3ccco3)n[nH]2)on1 +CCC1C(=O)Nc2ccc(C(O)C3CCCCC3)cc21 +COCCS(=O)(=O)N(C)CC(=O)N1CCNCC1 +CCC1CN(CC(=O)OC)c2cc(C(C)=O)ccc2O1 +Cc1ccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c(N(C)C)c1 +CN(c1ccccc1C(N)=O)S(=O)(=O)c1cn[nH]c1C(C)(C)C +C=CC1NCCc2ccc(F)c(Br)c21 +CC(C)N(C)S(=O)(=O)c1ccc(Cl)c(C(N)=O)c1 +Cc1ccc2c(c1O)CCNC2c1ncccc1Cl +O=C(Nc1ccc(OCC(F)(F)C(F)F)nc1)c1cc[nH]n1 +CC(=O)NCCNC(=O)NC(c1ccc(Cl)cc1)C1CCC1 +CCOC(=O)C1CC(=O)N(c2cc(C)c(Br)cc2C)C1 +OC(CNc1ccc(C(F)(F)F)cc1)c1cccs1 +CCn1ncc2[nH]c(-c3cnn(-c4cccc(F)c4)c3)nc21 +Cn1cc(C(=O)N2CCC3OCCC3(COc3cccnc3)C2)cn1 +COC(=O)c1[nH]c(C)cc1NS(=O)(=O)c1ccc(C)c(F)c1 +OC(c1cncc(Br)c1)C(F)(F)F +O=C(CCNC(=O)c1cc2n(n1)CCCO2)Nc1nccs1 +CCN(CCO)S(=O)(=O)c1cncc(Cl)c1 +O=C(c1ccno1)N1CCC(Oc2nc3ccccc3s2)CC1 +Cc1ccc(CCNC(=O)CCn2cnc3ccccc3c2=O)c(C)c1 +O=C(Nc1cccc(OCC(F)(F)F)c1)c1ccsc1 +CC(C)(O)C#Cc1cc(Br)cnc1N +COc1ccc(S(=O)(=O)CC(=O)NCCc2ccccc2)cc1 +O=C(NCc1ccc(Cn2cncn2)cc1)N1CCc2ccccc21 +CC(=O)Nc1cc(NC(=O)c2cc(C(C)C)[nH]n2)ccc1F +C=CCCOC(=O)c1nn(CC(C)C)c(=O)c2ccccc12 +CCC(Cl)(c1ccccc1)C(O)C(=O)OC(C)C +CCOc1cc(C2C(C(=O)OC)=C(C)Nc3nnnn32)ccc1O +CSc1nc(C)c(CC(=O)NC2CCCCC2)s1 +COC(=O)c1c(C)[nH]c(C(=O)NC2CCN(c3cccnc3)C2)c1C +O=C(CCn1ccccc1=O)NCC(=O)N1CCCC1 +O=S(=O)(NC(CC(F)(F)F)c1ccc(F)cc1)c1c[nH]cn1 +Cn1ccnc1SCC(=O)Nc1ccc2c(c1)OCCCO2 +CC1(COC(=O)c2ccc(CCNC(N)=O)cc2)CCCC1 +Cc1cccc(OCCn2c(C3CC(=O)N(C)C3)nc3ccccc32)c1 +CCN(CC)c1ccc(NC(=O)c2ccc(C(F)(F)F)nc2)cn1 +Cc1nc(CNC(=O)c2cccnc2OCC(F)(F)F)c(C)s1 +Cc1cc(C)n2nc(C(=O)N(C)CC(=O)NCC(F)(F)F)nc2n1 +O=C1Nc2c(cnn2-c2ccccc2Cl)C2=NCCCN12 +CCOc1ccc(C(=O)N(C)C)cc1NC(C)C +O=C1CCSc2c1cccc2C(=O)NCc1ccc(Cl)cc1 +COc1cc(NCc2ccccn2)c(OC)cc1Cl +COc1ccccc1C(=O)N1CCC(OCC(C)C)CC1 +CC(=O)Nc1cccc(C(=O)NCCc2ccc3c(c2)OCO3)n1 +Cc1ccc2c(CCNC(=O)C(C)n3cncn3)c[nH]c2c1 +CC(=O)Nc1nc2c(s1)CN(C(=O)C(C)Oc1ccccc1)CC2 +CCN(Cc1cccc(Cl)c1)C(=O)CSc1nncs1 +CCOc1cc(C(=O)C(C#N)c2ccccn2)ccc1OC +CC(C)(C)NS(=O)(=O)c1cccc(-n2cnnn2)c1 +COc1ccccc1C(=O)NC1CNCc2c(C)cccc21 +Cc1csc(CN(C)Cc2cccc(-c3ccncc3)c2)n1 +Cc1ccc(O)c(C(=O)NCc2cccc(OCC(=O)N(C)C)c2)c1 +OCCOCCNc1cc(-c2ccccc2F)nc2ccnn12 +Cc1ccc(C(O)CCC(=O)NC(C)C)cc1N +CN(CCOC(=O)c1cc(C(N)=O)cn1C)c1ccccc1 +Cc1ccc(N)cc1NC(=O)CCOC(C)CC(C)C +CCCC(=O)Nc1nn2c(CCC)nnc2s1 +COc1ccc(CNC(=O)c2cc(-c3cccs3)[nH]n2)cc1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)OCCCO3)c(C)c1 +C#CCOCC(O)CN1CCN(c2ccccc2)CC1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)C(C)NC(=O)C(C)(C)C +CC1CCCCN1S(=O)(=O)N(CCO)C1CCCC1 +CCc1cnc(N2CCC3(CC(n4cnnc4)CO3)C2)nc1 +CC(C)(C)OC(=O)N1CCC(COc2ncc(F)cn2)CC1 +COC(=O)Cc1csc(NC(=O)c2cccc(C)c2C)n1 +O=S(=O)(NCCOc1ccc(Cl)cc1)c1cccnc1 +Cc1c(C(=O)Nc2ccnn2C(C)C)cnn1-c1ccccn1 +Cc1cc(C(=O)NCCC(C)C)c2c(C)noc2n1 +O=C(NCC1(c2ccc(F)cc2)CCC1)C1CC2CCC1O2 +COCC(=O)N1CCC(S(=O)(=O)c2ccccc2)CC1 +Cc1ccc(S(=O)(=O)NCC(O)c2sccc2C)c(C)c1 +O=C1CCCN1Cc1nnc2n1CCN(Cc1ccsc1)CC2 +Oc1ccc2c(c1)OCC2Nc1ccc(F)c(F)c1 +CC(C)(CNC(=O)N1CCOCC1)c1ccc2c(c1)OCCO2 +O=C(NCc1ccc(Cn2cncn2)cc1)c1cc(Cl)ccc1O +CN(CC(C)(C)C)S(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +NC(=O)c1cccnc1SCc1cc(Cl)c2c(c1)OCO2 +Cc1[nH]c2ccccc2c1C(=O)N1CCOC(C)(C)C1 +N#Cc1ccccc1OS(=O)(=O)c1nccs1 +CCC1COCCN1CCC(N)c1ccccc1Cl +COCCCn1ccc(NC(=O)N(C)C(C)c2ccncc2)n1 +CCCCNC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1 +NC(=O)C1CN(Cc2cc(Br)cc3c2OCC3)CCO1 +OCc1nc2cccnc2n1Cc1cccc(Cl)c1 +Cc1cc(C)c(C)c(C(=O)CCC(=O)N2CCOCC2)c1C +CCc1nc(-c2ccc(NC(=O)NC3CC3)cc2)no1 +CCn1nnc(NC(=O)COc2cc(C)ccc2C(C)C)n1 +Cc1ccccc1-n1ncc(C(=O)Nc2ccc(F)c(C#N)c2)c1C +CCc1nnc(CN(C)C2N=CN=C3N=CC=C32)o1 +CCn1c(SCC(=O)NCC(N)=O)nc2ccccc21 +CCc1ccccc1-n1ccc2c(cnc3nc(C)nn32)c1=O +CCc1cc(C)cc(OCCNC(=O)c2nonc2N)c1 +CC(NC(=O)Cc1cccc(F)c1F)c1ccc(-n2cncn2)cc1 +COc1ccc(NC(=O)CC2C(=O)N=C(C)N=C2C)cn1 +Cn1cc(C(=O)N2CCCC3(CC(Oc4cccnc4)CO3)C2)cn1 +NS(=O)(=O)c1ccc(CCNC(=O)c2c(F)cccc2F)cc1 +Cc1nnc2n1CCN(CC(=O)NC(c1ccccc1)C1CC1)C2 +N#CC(NC(=O)CCc1ccncc1)c1cccc(Cl)c1Cl +Cc1cc(C(=O)N2CCCC(CNC(=O)c3ccco3)C2)nc(C)n1 +N#CCc1cccc(C(=O)N2CCCCC2CCO)c1 +CCN(C(=O)c1cccc(C)c1N)C(C)COC +OCCOc1ccc(CNc2ncc(C(F)(F)F)cc2Cl)cc1 +O=C(C1CCN(c2nc3ccc(F)cc3s2)CC1)N1CCCC1 +Cc1noc2nc(C(C)C)cc(C(=O)Nc3ccc(C(N)=O)cc3)c12 +N#Cc1ccnc(SCC(O)COc2cccc3[nH]ccc23)c1 +CCCCCC(C)NC(=O)NCc1cc(=O)[nH]c2ccccc12 +CCN(Cc1ccccc1)C(=O)CN1CCOC(Cn2cncn2)C1 +Cc1nnsc1C(=O)Nc1ccc(-n2cnnn2)cc1 +CCCS(=O)(=O)N(C)c1ccc(Cl)c(N)c1 +Cc1cc2c(=O)n(CC(=O)N(C)CC3CC3)cnc2s1 +Cc1ncc2c(n1)CCCC2NS(=O)(=O)c1c(C)noc1C +Cc1cc(C)c(NC(=O)CN(C)C(=O)c2ccc(=O)n(C)c2)c(C)c1 +O=S(=O)(N1CCCCC1)N(CCO)C1CCCCC1 +O=C(NCCCSc1ccccc1)NC1CCC(CO)CC1 +CCC(C)NC(=O)c1cccc(CNC(=O)c2ccncc2F)c1 +O=C(CS(=O)(=O)c1ccc(O)cc1)NCc1cccs1 +COc1ccc(C(=O)c2nc3ccccc3n2C(C)C)cc1OC +COCC(=O)Nc1ccc(NC(=O)Nc2cc(C)on2)cc1 +CNC(=O)CN(C)c1nc(C)c2ccc(S(C)(=O)=O)cc2n1 +CC(c1ccc(O)cc1)=c1sc2n(c1=O)CCN=2 +COCCOCC(=O)Nc1ccc(Cl)cc1N +O=C(Nc1ccnn1Cc1cccc(Br)c1)c1ccco1 +CC(C)CNC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1 +OCCc1cn(Cc2ccc(F)c(Br)c2)nn1 +COc1ccc(NC(=O)Nc2ccc(F)cc2)cc1F +CN1CCC(C(=O)NCc2ccnc(OC3CCCCC3)c2)CC1=O +Cc1cc(OCCc2ncc(CO)s2)ccc1Cl +CCCc1sc(C(=O)N2CCCC(c3nncn3C)C2)cc1CC +CC(=O)N(C)CC(=O)NCc1ccccc1OC(C)C +COc1ccccc1C(C)N(C)C(=O)Nc1cnn(C)c1 +CC(=O)N1CCN(C(=O)COc2ccc3ccccc3c2)CC1 +CC(C)(C#N)C(=O)OCc1cccc(OCC(N)=O)c1 +Cc1nn(Cc2ccc(F)cc2)c2[nH]nc(NC(=O)c3ccco3)c12 +COc1ccc(-c2nc(CNC(=O)Cc3cccc(C)c3)no2)cc1 +COC(=O)C1C2CCC(C2)C1NC(=O)c1cc2c(F)c(F)ccc2[nH]1 +Nc1cc(=O)[nH]c(SCCOCC(F)(F)F)n1 +O=C(NCC(=O)N1CCCCC1)c1cc2sccc2[nH]1 +Cc1cc(C(=O)NCCNc2nccc(C(F)(F)F)n2)c(C)s1 +CC(NC(=O)NCc1cscn1)c1ccc(OC(F)(F)F)cc1 +CC(C)n1cc2cc(C(=O)NCc3cccs3)sc2c1 +Cc1ccc(-n2nc3c(=O)n(CC(N)=O)nc(C)c3c2C)cc1 +Cc1ccc(C(O)CNC(=O)c2cccc(F)c2)cc1C +O=C(c1cc(Cl)ccc1F)N1CCN(c2nccs2)CC1 +CCOc1ccccc1C(=O)N(Cc1ccoc1)Cc1cccs1 +N#Cc1ccc(N2CCCC(N3CCNC3=O)C2)nc1 +Cc1cc(C)c(NCC(=O)Nc2cc(C)nn2C(C)(C)C)c(C)c1 +COC(=O)C(C)n1c(-c2cccs2)nc2c(N)cccc21 +CC1CN(CC(O)c2cccc(Cl)c2)CC(C(N)=O)O1 +O=C(NCc1cc2ccccc2[nH]1)N1CCOC2(CCC2)C1 +COc1cccc(C(=O)NCCOc2ccc(Cl)cn2)c1F +Cc1cc(C(=O)Nc2c(C)nn(C(C)C)c2C)no1 +CN(C)S(=O)(=O)NCC(C)(C)c1cccc(Cl)c1 +Cc1nc(-c2cccs2)sc1C(=O)N(C)CC(N)=O +COCC(NC(=O)c1ccccc1C(=O)c1ccc(F)cc1)C(N)=O +CCOc1ncccc1C(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +CSc1nnc(SCC(=O)Nc2c(C)cccc2C)s1 +Cc1nnc(C2CC3CN(C(=O)c4c(C)noc4C)CC3O2)o1 +CCOC(=O)c1sc(NC(=O)NC2CC2)cc1C +CCc1ccsc1C(=O)Nc1cccc(C(N)=O)c1C +CCOC1CC(N(C)C(=O)Cn2cnnn2)C12CCCC2 +COc1ccc(NC(=O)NCc2ccc(C)c(F)c2)cc1OC +Cc1ccccc1-n1cc(C(=O)NC(C)c2ccncc2)cn1 +Cc1ccc(C(=O)Nc2ccc(CN3CCOCC3)cc2)cc1 +O=C(NCCC1=CCCCC1)NC1CCC(O)CC1 +CCOC(=O)C(C)NC(=O)Cc1ccc(C)nc1 +CC(NC(=O)Nc1ccc(-n2ncc(C#N)c2N)cc1)c1cccnc1 +CNC(=O)c1ccc(NC(=O)c2ccccc2F)cc1 +O=C(CCn1cnc2sccc2c1=O)NCc1ccccc1F +CCNC(=O)c1cc(NC(=O)c2cncc(F)c2)nc2ccccc12 +CCOC(=O)N1CCN(C(=O)c2cc(F)ccc2C)CC1 +O=C(NCCNc1ncccn1)N1CCCC1c1cccs1 +Cc1ocnc1CNC(=O)Nc1cccc(N2CCC(C)CC2)c1 +CCc1cc(C(=O)N2CCN(c3ccccc3OC)CC2)no1 +CC(NC(=O)Cc1ccc[nH]1)C(C)N1CCOCC1 +O=C(CCNC(=O)c1ccoc1)NCc1ccc(Cl)cc1 +COc1nc(C)c(CC(=O)N2CCn3nc(C)nc3C2)c(OC)n1 +COCCCNC(=O)c1ccc(F)cc1Br +CC(=O)Nc1nc(COC(=O)c2ccc(C)cc2)cs1 +CN(C(=O)c1cccc(Br)c1)c1ccc(O)cc1 +COc1ccccc1CNC(=O)c1cc2ccoc2cn1 +Cc1nn(CCn2c(C)csc2=O)c(=O)c(C#N)c1C +CCCn1nc(-c2ccc(C)c(C)c2OC)cc(C#N)c1=O +Cc1cccc(CNC(=O)CNc2cc(C(N)=O)ccc2C)c1 +O=C(COc1cccc(C(=O)Nc2ccccc2)c1)NC1CC1 +COc1ccc(-n2nnc(C#N)c2-c2ccccc2C)cc1 +O=C(c1cc(Cl)c[nH]1)N1CCn2cccc2C1c1ccccc1 +O=C(c1cccnc1C(F)(F)F)N1CCc2cnccc21 +Cc1nn(C)c(NC(=O)c2cnn(CC(C)C)c2C(F)F)c1C +CCS(=O)(=O)N1CCCC(C(=O)Nc2cc(C)ccc2OC)C1 +COc1ccc(NC(=O)c2[nH]nc3c2COCC3)cc1OC +Cc1cccc(CN(C(=O)C(C)OCC(F)(F)F)C2CC2)c1 +Cc1cc(C)cc(C(=O)N2CCOCC2C2CC2)c1 +CCOC(C)c1nc(CNc2cc(CO)ccc2Cl)cs1 +CN(C(=O)c1ccccc1N)c1ccc2c(c1)OCCO2 +CCCCCCNC(=O)Nc1cccc(C(=O)N2CCOCC2)c1C +CN(CCC#N)C(=O)Nc1ccccc1OC(C)(C)C +COc1cccc(-c2[nH]ncc2C(=O)NCc2ccccc2Cl)c1 +CCCC1CN(C(=O)CCc2ccccc2)CCO1 +CC(C)c1ccc(NC(=O)c2cc(-c3ccncc3)[nH]n2)cc1 +O=C(CCc1nccs1)N1CCOC(c2ccc(Cl)cc2)C1 +CC(=O)c1c(NCc2ccccc2)nc(=O)n(-c2ccccc2)c1C +COc1c(C)cc(Cl)cc1S(=O)(=O)N(C)CCO +CC(=O)Nc1cccc(-c2ccc3[nH]ncc3c2)c1 +CC(=O)NCCNC(=O)N(C)Cc1ccc(Cl)cc1 +CN(Cc1ccccc1)C(=O)CCOc1ccccc1N +CC(C)CC(=O)N1CC(c2nc(-c3ccco3)no2)C1 +COc1ccc(NC(=O)Cn2cc(N)ccc2=O)cc1Cl +Nc1cccc2c(C(=O)Nc3ccc(Cl)cc3)nccc12 +Cc1cc(C(=O)Nn2c(C)nc3sccc3c2=O)on1 +Cc1oc(N)c(C#N)c1-c1ccc2c(c1)OCCO2 +O=C(CCc1ccccc1F)NCC1CN2CCCCC2CO1 +CCCn1ccc(NS(=O)(=O)c2cc(C)ccc2C)n1 +O=C(NC1CC1)c1ccc(N2CCC(n3cncn3)CC2)nc1 +COCC(NC(=O)c1ccc(-n2nc(C)cc2C)c(F)c1)C(N)=O +Cc1nc2ccc(C(=O)N3CCOCC(CO)C3)cc2o1 +O=C(Nc1ccc2c(c1)OCCO2)c1cc(Br)cs1 +CC(=O)N1CCCC(c2cnc(CCC(=O)NCC(N)=O)cn2)C1 +CC(C)Oc1ccc(C(=O)N2CC(=O)Nc3ccccc32)cc1 +COCCCNc1ncnc(-n2cnc3ccccc32)c1N +CC(=O)Oc1cccc(C(=O)NCc2cccnc2)c1 +Cn1nc(C(C)(C)C)cc1C(=O)Nc1ccn(CC#N)n1 +Cc1cc(-c2cnc(N(C)C)nc2CN(C)S(C)(=O)=O)on1 +CC(CNC(=O)Nc1ccc(S(C)(=O)=O)cc1)c1ccsc1 +Cc1cnn(CCC(=O)Nc2ccc(N(C)C(C)C)c(F)c2)c1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCCCCC2)cc1 +Cc1cccnc1NC(=O)c1scnc1C1CC1 +C=CCOc1ccc(CN2CCOC3(CCC3)C2)cc1OC +Cc1c(C(=O)Nc2cnn(CC3CCCO3)c2)oc2c(C)cccc12 +CCOC(=O)C(C#N)(Cc1cc(C)c(OC)c(C)c1)NC(C)=O +Cc1csc(-n2nc(-c3ccccc3)c3c2CCNC3)n1 +Cc1ccc(C(C)NC(=O)NC2CCN(C(=O)c3ccoc3)CC2)o1 +Cc1cc(C(=O)Nc2ccncc2)c2c(C)noc2n1 +CC(NC(=O)c1ccc[nH]c1=O)c1ccc(S(N)(=O)=O)cc1 +CC(C)c1ccccc1NCc1ccc(C(N)=O)cc1F +CC(C)N(CC1CC1)C(=O)c1ccc(F)cc1Br +O=C1N(CCO)c2ccc(Cl)cc2NC12CCCCC2 +O=C(NCc1cccnc1)c1nc(CC(=O)N2CCOCC2)no1 +CCC(C)NC(=O)C1CCN(C(=O)Nc2cccc(C)c2)CC1 +O=C(CCC(=O)N1CCOCC1)c1ccc2c(c1)CCCC2 +CC(=O)NCCNc1ccc(S(N)(=O)=O)cc1 +COCC(NC(=O)Nc1ccc(C(C)=O)c(C)c1)c1ccccc1 +COc1ccccc1OCC(=O)Nc1ccc2c(c1)CC(=O)N2 +Cc1ccc(C(=O)Cc2nc3ccccc3s2)o1 +COCCNC(=O)c1cc(=O)c2cc(N)cc(C(C)C)c2o1 +O=C(NCc1nc(-c2ccncc2)no1)c1ccc(C(F)(F)F)cc1 +COC(=O)NCC(=O)NC(C)Cc1ccccc1Cl +O=C(NC1CCCC(C2CC2)C1)c1scnc1C1CC1 +CC(C)(C)C(NC(=O)c1ccc(-n2ccnn2)cc1)C(N)=O +COCCNC(=O)c1ccn(COc2cc(C)cc(C)c2)n1 +CC(C)CN1CCOC(COC(=O)c2ccc3ccccc3n2)C1 +Cc1cc(C)c(CNC(=O)C2CC=CCC2)c(=O)[nH]1 +Cc1c(Cl)cccc1NC(=O)CCn1cnc2c(cnn2C)c1=O +N#Cc1ccc(-c2noc(CCSc3ccccn3)n2)nc1 +Cc1noc(COCC(=O)N(C)Cc2ccc(C)s2)n1 +CCc1ccccc1OC1CN(C(=O)c2ccccc2N(C)C)C1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)N1CCCC1c1ccsc1 +O=C(CCc1nc(-c2ccc3cc[nH]c3c2)no1)N1CCOCC1 +Cc1cc(C)c2nc(C)cc(C(=O)NCCCn3cnnc3)c2c1 +FC(F)(F)c1ccnn1-c1ccc(NCc2cscn2)cc1 +CCOC(=O)c1nc(CN2CCCc3cc(F)c(F)cc32)cs1 +CC1CCN(S(=O)(=O)c2ccc(NS(C)(=O)=O)cc2)CC1 +CCC(=O)Nc1cccc(C(=O)n2nnc3ccccc32)c1 +C=CCN1CCN(C(=O)c2csc(C)c2C)CC1 +Cc1[nH]c2ccccc2c1C(=O)NCc1cccc(OC(F)F)c1 +Clc1ccc(NCc2cccc(Cn3cncn3)c2)nc1 +O=C(CSc1nc(=O)[nH]c2c1CCCC2)Nc1ccc(F)cc1 +CC(=O)NCC1CCCN(C(=O)c2ccc(Cl)c(Cl)c2)C1 +CC1(C)CC2CC(C)(CN2C(=O)c2cc(C3CC3)on2)C1 +COc1cccc2cc(C(=O)OCC(=O)N3CCCC3)oc12 +Cc1ccccc1CCNC(=O)CCc1nc2ccccc2[nH]1 +N#Cc1cccc(CNS(=O)(=O)c2ccc3oc(=O)ccc3c2)c1 +COc1ccccc1NC(=O)c1ccc(NC(C)=O)cc1 +COc1c(Cl)cc(Cl)cc1CN(C)Cc1nc(C)cs1 +O=C(Cc1c[nH]c2ccccc12)Nc1ccc(NCCO)nc1 +O=C1CC2C(CCN2C(=O)c2ccoc2)N1Cc1cccnc1 +Cc1nn(C)cc1CN(C)C(=O)c1cccc(F)c1F +Cn1nc(C(=O)Nc2ccccc2)cc1NC(=O)c1ccco1 +COc1ccc(C(=O)N(CC2CC2)c2cc(Cl)ccc2C#N)nn1 +O=C(CNC(=O)Nc1ccc(Oc2ccc(F)cc2)nc1)NC1CC1 +COCCNC(=O)N(C)C(C)c1ccc(Cl)cc1 +COC(=O)c1cccc(C(=O)NCC(O)c2ccc(F)cc2)c1 +CCC(C)OC(=O)CN1C(=O)COc2cc(CO)ccc21 +COC(=O)c1cccc(CCNC(=O)Cc2cccc(O)c2)c1 +CCCC(C)NC(=O)C(C)Sc1nc(C)cc(N)n1 +CC(=O)Nc1ccccc1SCC(=O)Nc1ccc(C)cc1 +NC(=O)C1CCCN(C(=O)Cc2ccc(-n3cccc3)cc2)C1 +COC(=O)N1CCC(NC(=O)N(C)Cc2ccc(C#N)cc2)CC1 +Cc1cccc(C)c1NC(=O)CSc1nnc2n1CCCCC2 +CN(CCCNC(=O)Nc1nccs1)c1ccccc1F +CCOCCNC(=O)Cn1cnc2sc(C)cc2c1=O +CC(Sc1ncccn1)C(=O)Nc1cccc(F)c1F +Cc1cccc(C(=O)N(C)Cc2ccc(O)cc2)c1 +COc1cccc(C2=NC(=O)C(C#N)C(c3cccs3)=C2)c1 +O=C(NC1CCCC1)c1cc(Br)c[nH]1 +Cn1ncc(C(=O)NC2CCCCCC2)c1-n1cccc1 +O=C(c1ccccc1)N1CCN(Cc2ccccc2)c2ncccc21 +N#CCc1ccc(OCC(=O)N2CCN(CCO)CC2)cc1 +CC(=O)c1ccc(OCC(=O)Nc2c(C)cccc2C)cc1 +CNC(=O)Cc1ccc(NC(=O)C2CC=CCC2)cc1 +COc1ccccc1CNC(=O)c1nc[nH]c1C(=O)NC(C)C +C=CCNS(=O)(=O)c1ccc(C(=O)N2CCCC(C)C2)cc1 +CCc1n[nH]c(SCc2cc(=O)c3ccccc3[nH]2)n1 +CCC(=O)N1CCN(C(C)C(=O)Nc2ncccn2)CC1 +CCNC(=O)C1CCN(c2ccccc2F)CC1 +COc1ccc2nc(Nc3nc4cnccc4[nH]3)[nH]c2c1 +N#CCCC(C#N)CSc1nnnn1Cc1cccs1 +CC(C)N(C)C(=O)C1CCN(C(=O)CN(C)c2ccc(F)cc2)CC1 +CCS(=O)(=O)N1CCCC(NC(=O)OC(C)(C)C)C1 +CC(=O)c1nc(C)n(-c2ccc(Cl)cc2Cl)n1 +COc1ccc(CCNC(=O)Nc2cnc3c(c2)c(C)nn3C)cc1 +CC(C)(C)OC(=O)NCC(=O)NCC(C)(C)c1ccncc1 +CC(=O)Nc1ccc(C(=O)N(C)C(C)Cc2ccc(Cl)cc2)cc1 +Cc1cc(C)n(C2CN(CCc3nc4ccccc4c(=O)[nH]3)C2)n1 +O=C(COC(=O)C1=NC=CC1)NCC(=O)Nc1ccc(F)c(F)c1 +CCCCNC(=O)CN1CCN(C(C)C(=O)N2CCCC2)CC1 +NC(=O)Cn1c(-c2ccc(F)cc2)nc2ccccc21 +COc1cc(OC)c(C(=O)Nc2ccccc2C#N)cc1OC +O=C(CNC(=O)c1cc2scnc2[nH]1)Nc1cccc(Cl)c1 +CN(CCCOc1ccc(F)cc1)C(=O)c1cccc2nn[nH]c12 +COc1ccc(NC(C)=O)cc1NC(=O)c1cnc2ccccc2n1 +COc1ccc(CCC(=O)N2CCCC(C#N)C2)cc1OC +Cc1ccc(N2CCOC2=O)cc1NC(=O)Cc1ccc[nH]1 +Cc1ccc(CNC(=O)CCc2c(C)n[nH]c2C)cc1 +NC(=O)C1CCc2sc(NC(=O)c3ccccc3)nc21 +CC(=O)Nc1cccc(C(=O)Nc2cc(Cl)ccc2C)c1 +Cc1cccc(CC2Oc3cc(N)ccc3NC2=O)c1C +CNC(=O)Cc1cccc(NC(=O)N(Cc2noc(C)n2)C(C)C)c1 +CCN(CC(C)C)C(=O)c1cn(CC(=O)N(C)C)nn1 +CS(=O)(=O)N1CCCC(C(=O)N(CC2CCOC2)C2CC2)C1 +COC(=O)Cc1csc(NC(=O)c2ccc(F)c(F)c2)n1 +CCOC(CC)C(=O)Nc1cccc(-n2nnnc2C)c1 +CCOc1cc(F)ccc1NCC(=O)NCc1ccccc1F +CCOc1cc(C#N)ccc1OCC(=O)Nc1ccccc1 +CSc1nnc(SCC(=O)NCc2cc(F)cc(F)c2)s1 +Cc1nc2ccccc2c(=O)n1Cc1noc(C2CCCCC2)n1 +Cc1noc(C2(NC(=O)c3ccccc3C)CCCCC2)n1 +Fc1ccc2ncnc(N3CCN(c4cccc(Cl)c4)CC3)c2c1 +O=C(NCc1ccc2c(c1)OCCO2)c1cccc(-n2cnnn2)c1 +Nc1cc(N)nc(SCc2cc(F)ccc2Br)n1 +COc1ccc(F)cc1C(=O)c1cccc(N)c1C +CCOc1cc(C)c(-c2cc(C)n(C)c(=O)c2C#N)cc1C +CCN(C(=O)CC(C#N)C(=O)N1CCCCCC1)c1ccccc1 +Nc1cccc(Cn2c(=O)c(Cc3cccs3)nn3cnnc23)c1 +Cc1cc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)on1 +O=C1CCCCN1CC1CCN(C(=O)C2CCC2)CC1 +CSc1ccccc1C(=O)N1CCC(c2nnc(C(C)C)o2)CC1 +CCOCCCNC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +O=C(Nc1nc(C(=O)NC2CC2)cs1)c1cc(F)cc(F)c1 +NS(=O)(=O)CCNC(=O)c1cccc(F)c1F +CNS(=O)(=O)c1cc(C(=O)NC2(C)Cc3ccccc3C2)c(C)o1 +CCC1Oc2ncc(Br)cc2NC1=O +CCc1nnc(NC(=O)C(NC(=O)c2cccc(C)c2)C(C)C)s1 +COCC(=O)N1CCN(CCC(=O)N2CCc3ccccc32)CC1 +COC(=O)c1cc(NC(=O)Cc2c[nH]c3ccccc23)c(F)cc1F +CCC(Oc1ccc2c(c1)CCC2)C(=O)Nc1ccc(C(N)=O)cc1 +CC1CCc2c(sc3ncnc(N(C)CCO)c23)C1 +Cc1cc(C)n(C(C)C(=O)Nc2ccc(C)c(C)c2)n1 +COc1ccccc1C(=O)Nc1ccc(NC(C)=O)cc1 +CN(Cc1cc[nH]n1)C(=O)C1CCN(C(=O)C2CCCC2)CC1 +CCOc1nc(NCCc2ccncc2)ccc1N +Cc1nn(C)cc1-c1ccn(CC(=O)Nc2cnn(C)n2)n1 +Cc1ccc(OCCNC(=O)C2CCN(S(C)(=O)=O)CC2)cc1 +COc1ccccc1-c1nnc(C2CCN(C(=O)c3ccccc3)C2)o1 +Cc1nc(CCc2ccc(Cl)cc2Cl)nc(C)c1N +COc1nn(C)c2c1CCCN(C(=O)c1cccc3cccnc13)C2 +FC(F)(F)c1ccc(NCc2ccc(-n3ccnc3)nc2)nc1 +COc1ccc(C)cc1CC(=O)Nc1ccc(C(C)=O)cc1 +CCC1COCCN1C(=O)c1ccc(-c2noc(C3CC3)n2)cc1 +CCOCc1cccc(CNC(=O)c2cccnc2C)c1 +O=S(=O)(NCCSc1ccccc1)c1cn[nH]c1 +Cc1noc2nc(C(C)C)cc(C(=O)Nc3ccc4c(c3)COC4)c12 +COc1ccc2nc(SCC(=O)N3CCCCCC3)[nH]c2c1 +Nc1cc(-c2ccco2)nn1Cc1ccccc1Br +COC(=O)c1cc(CNC(=O)Cc2ccccc2C)oc1C +Cc1cccc(CNC(=O)CC(C)c2ccc(C(F)(F)F)cc2)n1 +Cc1cc(N2CC(C(=O)OC(C)C)CC2=O)ccc1Br +CCOc1ccccc1NC(=O)Cn1nc(C)c2c(C)onc2c1=O +COc1ccc(F)cc1C(=O)N(C)C1CCCC1 +COc1ccc(F)cc1NC(=O)c1sc(C(C)OC)nc1C +CC(NC(=O)C1CCC(=O)N1)c1nnc2n1CCCCC2 +CN(Cc1cnn(C)c1)S(=O)(=O)N1CCCCCC1 +CCOC(=O)c1nc2sc(C3CC3)nn2c1C#N +O=C(c1cccc2ccoc12)N1CCc2ccccc2C1 +COc1ccc(Br)cc1CC(=O)N1CCCC1 +Cc1sc2nc(C)n3c(=O)n(CC(=O)N4CCCC4)nc3c2c1C +CCOc1ccc(C(=O)NC2CCCCC2)cc1OCC +CC(C)Cn1nnc(CO)c1-c1ccc(F)c(F)c1F +Cc1cnn(CC(=O)Nc2ccc(C(F)(F)F)cc2)c1 +c1ccc2c(c1)c(NCCCN1CCOCC1)nn1nnnc21 +Cc1ccc(O)c(NC(=O)c2ccc(Br)cc2N)c1 +COc1ccc(C)cc1NCc1nc(C)c(C(C)=O)s1 +Cc1cccc(CC(=O)Nc2ccc3c(c2)CCC(=O)N3)c1 +CN1CC(C(=O)NC(CN2CCCC2=O)c2ccccc2)CC1=O +O=C(CCn1ccccc1=O)N1CC=C(c2ccccc2Cl)CC1 +Cc1nnc2n1CCN(CC(=O)N1CCc3ccccc31)C2 +CCc1cccc(C)c1NC(=O)c1ccc(CNC(N)=O)cc1 +O=C(CCc1nc(-c2cccnc2)no1)NCc1cc(F)cc(F)c1 +O=C(Nc1cc(-c2ccncc2)n[nH]1)C1CCCCC1 +CC(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2)CC1 +CCc1onc(C)c1NC(=O)c1cc(OC)cs1 +COCC1CCN(C(=O)Nc2ccn(-c3ncccc3Cl)n2)CC1 +CCC(=O)N1CCCC2CN(C(=O)CCCc3ccccc3)CCC21 +CCc1nnc2n1CCN(C(=O)CCc1ccc(C)c(Cl)c1)C2 +O=C(Nc1ccc2c(c1)OCCCO2)c1cc(-c2cccs2)on1 +CC(=O)Nc1ccc(S(=O)(=O)n2nc(C)c(C)c2C)cc1 +O=C(CN1CCN(c2ccc(O)cc2)CC1)NC1CCCC1 +CCSc1ccc(CNc2cccc(O)c2)cc1 +NC(=O)c1cncc(Oc2ncnc3c2oc2ccccc23)c1 +COCc1ccc(CNC(=O)COc2ccc(C)cc2)cc1 +CCC(=O)Nc1ccc2c(COC)cc(=O)[nH]c2c1 +CC(=O)Nc1ccc(NCC(=O)c2ccccc2)cc1 +Cc1c(C(=O)N2CC3OCCN(C)C3C2)cnn1-c1ccncc1 +O=C(NCc1ccco1)c1nc(-c2ccc(Cn3ccnc3)cc2)no1 +COC(=O)Cc1cc(=O)c2cccc(Cl)c2[nH]1 +CCOc1ccc2nc(C(=O)NCc3cccc(Cl)c3)cn2n1 +Cc1ccc(S(=O)(=O)NC(C)(C)c2nc(C)c(C)s2)c(F)c1 +CCNc1nc(Oc2ccc(=O)[nH]n2)nc(N2CCOCC2)n1 +O=C(NC1CCC1)C1CC2CN(C(=O)c3ccno3)CC2C1 +CCc1ncc2c(n1)CN(C(=O)c1cc3c(C)cccc3n1C)C2 +COc1ccc(CNC(=O)c2cc(CC(C)C)n[nH]2)cc1 +CCOC(=O)c1c[nH]c2ccc(NC(=O)c3cccnc3)cc2c1=O +CC(C)CC(O)c1nc(C(C)(C)C)nn1CCO +Cc1cc2cc(C(=O)N3Cc4cnn(CCO)c4C3)ccc2o1 +Cc1ccsc1CNCc1cccnc1OCC(F)(F)F +Cc1nc(C)n(Cc2cccc(OCC(F)(F)F)c2)n1 +CCCC(=O)N1CCC(c2nn(CCNC(C)=O)c3ncccc23)C1 +O=C1CCc2cc(NC(=O)c3cc4ccccc4[nH]3)ccc2N1 +C=CCOc1ccc(OCc2nsc(N(C)C)n2)cc1 +CC(C)(C)c1cc(NC(=O)COc2ccccc2C#N)on1 +O=C(c1ccncc1)N1CCN(C(=O)c2ccccc2O)CC1 +CC(NC(=O)Cc1ccc[nH]1)c1nnnn1-c1ccccc1 +CC(C)(C)OC(=O)N1CCN(Cc2nc3ccccc3[nH]2)CC1 +N#Cc1ccc(Nc2ccc(CN3CCOCC3)cc2)nn1 +CC(=O)NC1CCCN(C(=O)NCCOc2ccc(C(C)C)cc2)C1 +O=C(c1cn2c(n1)CCCC2)N1CCN(c2ccccc2F)CC1 +Cc1ccc2cnn(CC(=O)N3CC(C)CC(C)C3)c2c1 +O=C(Nc1nncs1)C1CC(=O)N(c2ccc(F)cc2)C1 +NC(=O)c1ccc(NC(=O)NC2CCCc3occc32)cn1 +CC(C)OCc1cccc(NC(=O)c2n[nH]c3ccccc23)c1 +CCOC(=O)C1CCN(C(=O)c2c(C)nsc2NC)CC1 +CN1CCOC(C(=O)N2CCC(OCCCc3ccccc3)C2)C1 +CCNc1nc2c(cc(OCC)c3ncccc32)s1 +Cc1ccc(C(=O)NCCc2ccccc2F)cc1 +Cc1cc(CNC(=O)Cc2csc(C)n2)c(C)o1 +CCc1n[nH]c(SCC(=O)Nc2ccc(Cl)cc2C)n1 +Cc1ccc(-c2n[nH]c(NC(=O)CCc3ccccc3O)n2)s1 +COc1c(C)cc(C)cc1C(=O)Cn1cc(N)cn1 +Cc1cccnc1NC1=NS(=O)(=O)c2ccccc21 +COc1c(F)ccc2c1C(c1ncccc1Cl)NCC2 +CC(C)CN1CCn2c(nc3cc(NC(=O)c4ccco4)ccc32)C1 +COC(C)(C)c1noc(C(C)Oc2ccc(C#N)cc2)n1 +CC(=O)OC1CCN(C(=O)Nc2ccc3c(c2)COC3)CC1 +CCOc1ccc(F)c(C(=O)NC2CCN(C(=O)OC)C2)c1F +Cc1ccc(-c2ncco2)cc1NC(=O)NCCCC(C)(C)CO +Cc1ccc(CN2CC(C(=O)NC3(CO)CCCC3)CC2=O)cc1 +CN(C)C(C(=O)NCCCn1cc(Cl)cn1)c1ccc(F)cc1 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1ccccc1C(F)(F)F +Cc1nc2nc(N3CCCC3)[nH]c(=O)c2cc1C(C)O +Cc1cnc(NC(=O)c2ccc(CNC(=O)NC(C)C)cc2)s1 +CNC(=O)CSc1ncccc1-c1noc(C2CC2)n1 +CSc1nnc(CSc2n[nH]c(N)n2)s1 +CCCS(=O)(=O)NC(C)C(=O)N1CCOCC1 +CCc1noc(CC)c1CC(=O)NCc1cccc(C)n1 +COCC(O)CN(C)S(=O)(=O)c1cccc(N)c1 +O=C(CCc1ncc(-c2ccc(F)cc2)o1)N1CCCS1(=O)=O +CCc1cccc2c(C#N)c3c(nc12)CCN(CC)C3 +O=C(c1cnc(-c2ccccn2)s1)N1CCCC1Cn1cccn1 +Nc1nc2n(n1)CCCC2c1cccc(C(F)(F)F)c1 +CN1CC(C(=O)NC2CC2c2ccccc2C(F)(F)F)CC1=O +O=C(Cn1nc(-c2ccccc2)ccc1=O)NCCc1ccccn1 +Cc1cc(OC(=O)CNC(=O)C(C)(C)C)ccc1Cl +O=C(CNC(=O)c1ccc(C(F)(F)F)cc1)c1ccccc1 +O=C(Nc1ccc2c(c1)OCO2)NC1CC(=O)N(c2ccccc2)C1 +CCOC(=O)c1cc(C)sc1NC(=O)Cn1cccc(C)c1=O +O=C(c1cc(Br)c[nH]1)N(CCO)CC(F)(F)F +O=C(CCn1cccn1)NCc1ccccc1Cl +CCn1cc(CN(Cc2ccccc2)Cc2ccncc2)c(C)n1 +NC(=O)c1ccc(NC(=O)CCc2nc3ncccc3[nH]2)cc1 +O=C(COc1ncnc2ccccc12)NCCCc1ccccc1 +CC(C)Nc1ccc(C(=O)Nc2ccc3ncccc3c2)cn1 +COc1ccc(-c2ccn(C)c(=O)c2C#N)c(OC)c1 +CCc1nc(C)c2c(C)c(C(=O)N(CC)CC)sc2n1 +Cc1cc(CNc2ccccc2SCC(F)(F)F)no1 +CCCc1n[nH]c(C2CN(Cc3ccn(C)c(=O)c3)CCO2)n1 +Cc1nc2ccc(NC(=O)C(C)Oc3ccc(C#N)cc3)cc2o1 +CCOC(=O)c1noc(C(=O)N(CC)CC)c1N +CCOc1ccc(C(=O)OCc2c(C)noc2C)cc1 +Cc1cccc(CN(C2CC2)S(=O)(=O)N2CCCCC2)c1 +CC=Cc1ccc(OCC(=O)Nc2c(C)cccc2C)c(OC)c1 +CN(Cc1ccccc1)C(=O)CSc1nncn1N +CC(=O)NC(C(=O)Nc1ccc(-c2nccs2)cc1)C(C)C +CS(=O)(=O)c1ccc(NC(=O)c2ccncc2)cc1 +O=C1NCCCc2[nH]c(Cc3cnn(-c4ccccc4)c3)nc21 +CCCCc1ccc(C(O)C(=O)N2CCNCC2)cc1 +COCCNC(=O)Nc1ccc(OCc2cccc(C#N)c2)cc1C +CC(OC(=O)c1ccccc1-n1cnnn1)C(N)=O +Cc1ccc(O)c(C(=O)NCc2ccc(NC(N)=O)cc2)c1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)c2cc3ccccc3o2)c1C +COc1cc(OC)c(NC(=O)c2ccc3c(c2)OCCO3)cc1Cl +CCCc1noc(CNc2ccccc2NC(=O)c2ccccc2)n1 +CN(Cc1ccc(Br)cc1)C(=O)c1ccc(F)c(F)c1 +Cc1ncc(CNC(=O)Nc2ccccc2N2CCCCC2)s1 +CN(C)c1ccc(C(=O)Nc2c[nH]ccc2=O)cc1F +Cc1cc(C)nc(SC(C)C(=O)Nc2nccs2)n1 +Cc1ccc(-n2ccc(C)c(C#N)c2=O)cc1Cl +Cc1nnnn1-c1cccc(NC(=O)CN(C)C(=O)OC(C)(C)C)c1 +N#Cc1cccc(NCc2ccc(O)c3ncccc23)c1 +COC(CNS(=O)(=O)c1ccc(F)cc1C)c1ccc(C)s1 +COCC(=O)N1CCCC(c2nc(N)ncc2-c2ccc(F)cc2)C1 +COCCn1c(-c2cccs2)ccc(C#N)c1=O +CN1C(=O)CC(C(=O)NCC2CCC(C)(C)CC2)C1c1cccnc1 +Cc1cc(OC(=O)CCc2cnn(C)c2)ccc1C(C)C +COc1ccccc1CC(C)N(C)Cc1ccc(-n2cncn2)cc1 +CN(CC(=O)N1CCOCC1)c1ccc(C#N)cn1 +Cc1nc(CNC(=O)N2CCN(c3ccc(Cl)cn3)CC2)no1 +Cc1nc(C)c(C(=O)NCc2cccc(C(=O)Nc3ccccc3)c2)o1 +COCCNC(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1 +CC(Cn1cccn1)NC(=O)Nc1nnc(C2CCCCC2)s1 +CCn1cc(CC(=O)Nc2cc(OC)ccn2)c2ccccc21 +CC(CC(=O)NCc1cccc(C#N)c1)c1ccncc1 +O=C(Cc1coc2ccc(F)cc12)Nc1ccc(Cl)cc1 +O=C(CCc1ccc(Br)cc1F)NCC(=O)NC1CC1 +CCOC1C2CCC1N(C(=O)c1ccc(F)c(OC)c1)CCO2 +CC(=O)Nc1cccc(-c2ccc(-c3ccccc3)nn2)c1 +COc1ccc(C(=O)OC(C)c2ccccn2)c(OC)c1 +CCCOc1ccc(C(=O)N2CCCC(C)C2)cc1OCC +CC(C)COC(=O)Cn1c(=O)[nH]c2ccccc2c1=O +N#Cc1cnc(N2CCN(Cc3cncnc3)CC2)nc1N +CNS(=O)(=O)c1ccc(CNC(=O)c2ccc(=O)n(C)c2)cc1 +CCOC(=O)CCC(=O)c1ccc2ccccc2c1 +CCC1(O)CCN(C(=O)Cc2c(C)[nH]c(=O)[nH]c2=O)CC1O +C=CCNc1nnc(SCc2nc(C(C)C)no2)s1 +Cc1cc(C)c(NC(=O)CNS(=O)(=O)Cc2ccccc2)c(C)c1 +Cc1cccc(C)c1NC(=O)C(C)Sc1ncccc1Cl +CC(=O)Nc1ccc(F)c(NC(=O)C2CC=CCC2)c1 +CC(=O)NC1CCCN(C(=O)Nc2cc(Cl)ccc2Cl)C1 +CC(C)CNC(=O)CSc1nncc(=O)n1N +N#CCCC(C#N)Cn1nnc(-c2ccc(Br)cc2)n1 +Cc1cccc(NC(=O)CSc2nnc(-c3ccccn3)n2C)c1 +O=C(NC1CCCCC1)c1c(F)c(F)cc(F)c1F +Nc1ccc(SCC(=O)NCc2cccs2)cc1 +O=C(NCCNC(=O)c1ccoc1)c1ccncc1 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+CCOc1cc(C)ccc1NC(=O)c1cc(C)nc2c1c(C)nn2C +CC(=O)NCC(=O)N1CCCn2c(CN3CCCC3=O)nnc2C1 +CNC(=O)c1ccc(CN(C)C(=O)c2cn3cccnc3n2)cc1 +O=C(COc1ccc(Cl)cc1)NCCNC(=O)c1ccccn1 +O=C(NC1CCCc2ccccc21)c1ccccn1 +CC(C)OC(=O)c1nnn(Cc2ccc(F)cc2)c1N +Cc1ccc(CNC(=O)Cc2noc3ccccc23)s1 +CCN(CC)C(=O)Cn1nc(-c2ccc(C)s2)cc(N)c1=O +CC1=NC(C)=C(C(N)=O)C(c2ccc(Cl)cc2)C1C(N)=O +NC(=O)CC1CCN(C(=O)c2ccc(NC3CC3)nc2)CC1 +CC(C)(C)NC(=O)Nc1ccc2c(c1)CCC(=O)N2 +CCN(CC(C)C#N)C(=O)c1coc2ccccc12 +CCOC1CC(NC(=O)CNC(=O)NC)C12CCCCC2 +CCOc1ccccc1C(=O)N1CCN(Cc2ccsc2)CC1 +NC(=O)C1Cc2ccccc2CN1C(=O)CC1CCCCC1 +Cn1ncc2cc(C(=O)NCc3ccco3)c(N)nc21 +CCNC(=O)CSc1nc2ccccc2n1CC +CCN1CC(C(=O)NCCc2nc3ccccc3n2CC)CCC1=O +O=C(OCc1cc(=O)n2ccsc2n1)C1(c2ccccc2)CC1 +O=S(=O)(NCCc1ncc2ccccn12)c1ccc2c(c1)OCO2 +CCN(CC)C(=O)CN1CCN(c2ccccc2F)C1=O +Cc1oc2cc(O)ccc2c(=O)c1-c1nncn1-c1ccccc1 +COC(=O)CSc1nnc(CNc2ccc(F)cc2)o1 +O=C(CN1CCc2ccc(Cl)cc2C1)Nc1nccs1 +CCNC(=O)c1cccc(CNC(=O)NCC(C)(C)C(N)=O)c1 +Cc1cc(C(C)NS(=O)(=O)N2CC(C)OC(C)C2)c(C)o1 +COc1cc(NCCC(C)(C)C)ccc1NS(C)(=O)=O +Cc1nnsc1C(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +COc1cc(CNC(=O)c2ccsc2)ccc1OC1CCCC1 +CC(CC#N)NC(c1ccccc1)c1ccccc1 +Cc1ccc(C(=O)NC(c2ccc(Cl)cc2)C2CC2)c(=O)[nH]1 +Cc1ccccc1NC(=O)CSc1nc(=O)n2cccc(C)c2n1 +Cc1ccc(F)c(NC(=O)c2c(Cl)cnn2C)c1 +CCCCCn1cc(C(=O)NCCC)c(=O)c2c(N)cccc21 +CCc1nc(CC(=O)NC(C)C(=O)N(C)C)cs1 +CC1(C)C2CC=C(COC(=O)c3c[nH]c(=O)c(Cl)c3)C1C2 +Cc1cccc(NC(=O)COCc2cc(-c3ccc(F)cc3)on2)n1 +COCC(=O)N1CCCC(c2cccc(C(N)=O)n2)C1 +COCCOc1ccc(Cl)cc1S(=O)(=O)NC1CC=CC1 +COCCOc1ncccc1C(=O)Nc1ccc(Cl)cn1 +CCC(C)NS(=O)(=O)c1ccc(NC(=O)c2ccco2)cc1 +CCn1c(SCC(=O)Nc2cccnc2)nnc1-c1cccs1 +CCC(C(=O)OCC(C)C)n1nnc(C(C)=O)c1C +CC(C)Nc1cc(-c2ccccc2C(F)(F)F)n[nH]1 +CN(Cc1ccccc1F)C(=O)Nc1ccc2c(c1)oc(=O)n2C +CCOc1ccccc1-n1nnnc1SC(C)C +CC(=O)NC1CCN(c2ccccc2C(=O)N(C)C(C)C)CC1 +CCNc1nnc(-c2cccn(C3CC3)c2=O)s1 +Cc1ccnc(NC(=O)Cc2c(C)nn(C)c2C)c1 +CC(=O)Nc1cc(C(F)(F)F)nn1-c1ccc(C)c(C)c1 +COc1ccc(S(=O)(=O)NCCCN2CCCC2=O)cc1C +CC(=O)Nc1ccc(F)c(C(=O)NC(c2ccccc2)C(C)C)c1 +COc1ccc(-c2cn3ccc(C)cc3n2)c(OC)c1 +COc1cccc(C(C)N(C(=O)c2ocnc2C)c2cnn(C)c2)c1 +Nc1ccc2c(c1)OCCN2C(=O)Cc1c[nH]c2ccccc12 +CC(C)Oc1cc(F)cc(-c2cnn(CCO)c2)c1 +CCn1cc(C(=O)NCc2ccc(OC)nc2)cn1 +O=C(CNCc1cccnc1)Nc1ccc(OC(F)(F)F)cc1 +CCc1n[nH]c(C(=O)N2CCc3sccc3C2C)c1C +COc1cccc(-c2cc(C#N)c3c(c2)CCCN3)c1 +COc1ccc2c(c1)cc(C(=O)N1CCCC3(CCCO3)CC1)n2C +Cc1ccc(NS(=O)(=O)N2CCOCC2)cc1Br +Cn1ncc2c(=O)n(CCC(=O)NCCc3cccc(F)c3)cnc21 +Cc1cccc(C)c1CNc1ccc(C#N)c(C#N)c1 +CNc1nn2c(=O)c(-c3cn(C)c4ccccc34)nnc2s1 +Cc1nc(C(=O)N2CCCC(c3noc(C(C)C)n3)C2)c[nH]1 +Cn1cc(CN2CCC3C2CCN3c2nncs2)cn1 +O=C(CNC(=O)C1CC2C=CC1C2)Nc1ccc(-n2cccn2)cc1 +CC(C)(C)NC(=O)CNC(=O)Nc1ccc(-c2nccs2)cc1 +O=C(CC1CCCN1C(=O)Cc1ccc[nH]1)c1ccccc1 +COc1ccc(C(=O)NCC(C)(C)N2CCOCC2)cc1 +O=C(Cn1c(-c2cccs2)cc2cc(F)ccc21)NC1CCCC1 +Cc1cccc(C(=O)NCCCCNC(=O)c2cccc(C)c2)c1 +COc1cccc2c(C)cc(=O)n(C(C)C(=O)N3CCCC3)c12 +CCc1nnc(NC(=O)C(C)NC(=O)c2ccco2)s1 +CN(C)S(=O)(=O)c1ccc(-c2csnn2)s1 +Cn1ccnc1SCC1CCN(C(=O)c2ccsc2)CC1 +CCn1cc(O)c(=O)cc1CN(Cc1ccccc1)C(C)C 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+Cc1cc(C)n2ncc(CN(C)C(C)Cc3ccccn3)c2n1 +CC(=O)c1ccccc1OCCOC(=O)c1cccc(O)c1 +Cc1ccc(C(=O)N2CC(Oc3ccccn3)C3OCCCC32)cn1 +Cc1nc(N)nc(-c2ccc3c(c2)C(C)(C)C(=O)N3C)n1 +Cc1ccc(CNc2ccccc2C(N)=O)cc1C +COC(=O)Cn1nc(-c2ccncc2)nc1-c1ccncc1 +O=C(CCc1ccsc1)NC1CCN(c2ncccn2)CC1 +CCc1ccc(CNC(=O)Nc2ccc(CC(=O)N(C)C)cc2)s1 +CCOC(=O)C(Cc1cnc(C(C)(C)C)nc1)NC +O=C(CCn1ccc2ccccc21)NCC(O)c1ccc(F)c(F)c1 +CCOc1ccc(C2NC(=O)NC3=C2C(=O)N(CCOC)C3)cc1 +O=C(CCc1cccnc1)Nc1ccc(N2CCCC2=O)cc1 +Cc1nc(CNC(=O)c2sc3ccccc3c2C)c(C)s1 +CCc1nn(CC(=O)N2CCc3ccccc3C2)c(=O)c2cccn12 +N#Cc1c(COC(=O)c2cc3ccccc3oc2=O)cn2ccccc12 +Cc1nc(CC(=O)NCC2(c3cccc(F)c3)CCOCC2)cs1 +CCN(Cc1ccccc1)C(=O)CNC(=O)C1CC1C +CCN(CC(=O)Nc1ccccc1C(F)(F)F)C(=O)c1ccco1 +COc1ccnc(N2CCN(CC(O)c3ccc(F)cc3)CC2)n1 +CC(Oc1ccccc1Cl)C(=O)Nc1cc(N)ccc1F +Cn1cc(CCOC(=O)c2ccccc2Cn2cncn2)cn1 +CC(CNC(=O)C(C)S(=O)(=O)c1ccc(O)cc1)c1ccccc1 +O=C(Nc1ccccc1)C1CCCN(C(=O)Nc2ccccc2)C1 +Cc1cc(F)cc2c1CCNC2C=Cc1ccncc1 +COC(=O)CNC(=O)c1cc(-c2cccc(Cl)c2)on1 +Cc1ccccc1-n1ncc(C(=O)N2CCOCC2)c1C +CCc1cc(-c2csc(C#N)c2NC(C)=O)ccc1OC +Brc1cc2c(c3c1C1(CC1)CNC3)OCCO2 +CC(=O)c1ccccc1NC(=O)CSc1nnnn1C +CC1=C(C(=O)Nc2cccc(C)c2)C(c2cccnc2)n2nnnc2N1 +Cc1ccc(C(=O)NCc2cc(C(C)C)no2)cc1 +COc1ccc(C(O)CNc2nc3ccccc3cc2CO)cc1 +Cc1nc(N(C)C)sc1CN1CCCC1C(=O)OC(C)C +N#Cc1cc(NC(=O)Nc2cc[nH]n2)ccc1Cl +CCCc1nnc(NC(=O)CCOc2ccccc2F)s1 +CCC(CC)C(=O)Nc1ccc(-c2ncc[nH]2)cc1 +c1ccc(-n2nc(CSc3nncs3)c3c2CCC3)cc1 +CC(=O)c1ccc(NC(=O)CC(C#N)c2ccccc2F)cc1 +COc1ccc(Cl)cc1CNC(=O)NCCc1cscn1 +CN1CCN(C(=O)c2csc(-c3ccc4c(c3)OCO4)n2)CC1 +CCOC(=O)C1CCN(C(=O)c2cc(Cl)ccc2F)CC1 +COc1cccc(C(=O)Nc2cccn3cnnc23)c1OC +CCOCc1ccccc1NC(=O)NCc1ccc(O)c(OC)c1 +Cc1cc(C)n(CC(=O)N2CCCN(c3ncccc3C#N)CC2)n1 +Cc1ccc(S(=O)(=O)NC(=O)NCC2CC3C=CC2C3)cc1 +COc1cc(C(C)=O)ccc1OCc1cccc2cccnc12 +CC(Sc1ccccc1Cl)C(=O)OCCN1CCCC1=O +COC(=O)c1ccc(C(=O)N2CC(C)CC(C)C2)cc1 +CCNC(=O)C(C)NC(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CCCCn1nnnc1NC(=O)N(C)CC1CCCCO1 +Cn1cc(C(=O)NCCc2cccs2)c(C(C)(C)C)n1 +Cc1ccc(-c2ccc(=O)n(CC(=O)Nc3ccc(F)cc3)n2)cc1 +CCNC(=O)CNc1cccc(S(=O)(=O)N2CCCCC2)c1 +COCC(C)(O)CNS(=O)(=O)c1ccc(Br)cc1 +COCCNC(=O)NCC1CCN(c2cc(Cl)ccc2C)C1 +COc1ccc(CSc2nc(C)n[nH]2)cc1Br +CCOC(=O)C(C)(N)CSc1ncnc2nc[nH]c12 +COc1ccc(C(=O)NCc2cc(F)cc3c2OCOC3)cc1OC +CCC1(O)CCN(C(=O)c2ccc(SC)cc2)CC1O +Cc1noc(C)c1S(=O)(=O)NC1CCCC(O)C1 +CC(=O)c1cccc(NC(=O)Cn2cc(N)cn2)c1 +CC(NC(=O)COc1ccccc1Br)C(=O)N(C)C +Cc1ccc(NCc2ccc3c(c2)OCCO3)cc1 +Cc1ccc(CC(=O)Oc2cc(Cl)cc(Cl)c2)cn1 +Cc1ccc(OCC(=O)NC(C)c2ccc(Cl)cc2)nc1 +Cc1ccc(C(C)NC(=O)c2ccc(S(C)=O)cc2)cc1F +COCCOCc1cc(C#CCO)ccc1OC +CCc1nc(CC(=O)N2CCCCC2Cn2nc(C)cc2C)cs1 +CN(C(=O)NCC1CCCO1)C1CCN(c2ccc(F)cc2)CC1 +CN(c1ccc(O)cc1)c1ccc2ncccc2c1 +COc1ccccc1C(O)CNC(=O)c1cccs1 +CCc1ccc(N2CC(C(=O)N(CCO)CC3CC3)CC2=O)cc1 +O=C(NC1CCN(c2ccccc2)C1=O)c1c[nH]c2ccccc2c1=O +Cn1cc(S(=O)(=O)Nc2ccc(F)cc2Cl)cc1C(N)=O +Cc1nc(C)c(C(=O)NCCNc2ccc(-n3cccn3)nn2)s1 +COc1ccc(OC)c(-c2nc3c(N)cc(C)cn3c2C)c1 +Cc1ccc2c(c1)S(=O)(=O)N=C(NC1CCCC1)N2 +O=C(NCC1CCCO1)c1ccc(N2CCCCCC2)nc1 +CCOC1CCCN(C(=O)Nc2ccc(F)c(-n3nnnc3C)c2)C1 +CCc1nn(C)cc1CN(Cc1nc2ccccc2c(=O)[nH]1)C(C)C +CCCNC(=O)c1cc(NC(C)=O)cc(NC(C)=O)c1 +C=C(C)Cn1c(CCNC(=O)C2CC2)nc2ccccc21 +Cc1cn(S(=O)(=O)c2ccc(Cl)cc2)c(=O)[nH]1 +CC(=O)NC(CC(C)C)C1NCCc2c(C)ccc(F)c21 +N#Cc1ccccc1OCC(=O)c1ccccc1F +CCNC(=O)CN1CCN(C(=O)CCOc2cc(C)cc(C)c2)CC1 +Cc1cc(C(=O)NCCNc2nnnn2-c2ccccc2)sc1C +CCOc1cc(Cl)ccc1S(=O)(=O)n1cccn1 +CCOC(=O)NC1CCN(c2cc(C)nc(N)n2)CC1 +Cc1ccc(CN(C(=O)Nc2ccc(-n3cncn3)cc2)C(C)C)o1 +COc1cc(Cl)c(S(=O)(=O)Oc2ccccn2)cc1Cl +Cn1c(CCC(N)=O)nnc1SCC1CCCC1 +Cc1ccc(CNC(=O)C2CCCN(C(N)=O)C2)s1 +CCNc1nc(-c2sc(CC(C)C)nc2C)cs1 +FC(F)(F)Oc1ccc2c(c1)C(c1ccccn1)NCC2 +COc1ccccc1OCC(=O)Nc1cc(F)ccc1F +COc1cccc(-c2ccc(C(=O)N3CCOCC3)cn2)c1 +CC(=O)Nc1ccc(NC(=O)c2cc(NC(=O)C3CC3)n(C)n2)cc1 +CC(C)Cc1cc(CNC(=O)C2CCOc3ccccc3C2)on1 +Cc1nc(NCCc2ccccc2)cc(C(=O)N2CCOCC2)n1 +CCC(CO)NC(=O)NC(C)c1ccccc1Cl +COCCN(Cc1ccccc1)S(=O)(=O)N1CC(C)CC(C)C1 +Cc1cccc(NC(=O)CCNC(=O)NCc2ccccc2)c1C +COCc1ccc(C(=O)N2CCc3cc(SC)ccc3C2)s1 +CCc1ncc(C(=O)N(Cc2ccccn2)C2CCCCC2)cn1 +N#Cc1ccc(C(=O)NCCCN2CCOC(c3ccccc3)C2)cc1 +O=C(Cn1ccccc1=O)Nc1ccc(Cl)cc1 +O=C(NCc1ccc(F)cc1)Nc1nc2c(s1)CCC2 +Cc1nc(Cn2ccnc2-c2cncc(Br)c2)cs1 +COc1cc(C(=O)N2CCNC(=O)C2(C)C)cc(OC)c1OC +O=C(C1CCCO1)N1CCC(CCOc2ccccc2F)CC1 +COCCn1nc(C(=O)Nc2cccc(Cl)c2OC)ccc1=O +N#Cc1ccc(C(=O)NC2CC(=O)N(C3CC3)C2)cc1 +CCOC(=O)Nc1ccc2nc(CCCO)[nH]c2c1 +N#Cc1c(F)cccc1NCCCN1CCOCC1 +O=C(Cc1ccc2c(c1)NC(=O)CS2)NCCCO +N#Cc1c(-c2ccc3c(c2)OCCCO3)c[nH]c1N +Cc1ccsc1C(=O)OCCN1CCOC1=O +O=C(CSc1nnc(-c2ccco2)o1)N1CCCCC1 +CC(C)NC(=O)c1cc2occc2n1Cc1ccccc1 +COc1ccc(C=Cc2nc(C#N)c(N(C)C)o2)cc1OC +CCN(C(=O)Cn1cnnn1)C(C)c1cc2ccccc2o1 +CC(C)CCNC(=O)c1ccc2c(c1)nc1n2CCOC1 +Cc1nc(N2CCN(C(=O)C3CC3)CC2)c2c(n1)c(C)nn2C +Cc1ccc(-c2nn(-c3ccccc3)cc2C(=O)NC2CC2)o1 +Cc1ccc(OCCn2nnn(-c3ccccc3)c2=O)cc1 +CC(=O)N1CCC2(CC1)CN(C(=O)C1CCCCC1)C2 +Cc1ccc(N(C)C(=O)C2CCN(C(=O)C(C)C)CC2)c(C)c1 +FC(F)(F)c1cnc(NCc2cccnc2)c(Cl)c1 +COc1ccc(C(=O)CCC(=O)NC(C)(C)C)c(OC)c1 +CCCS(=O)(=O)N1CCC(C(=O)NCc2ccc(C)cc2)CC1 +CCc1ccccc1Nc1noc2c1CN(C(=O)c1ccccn1)CC2 +CCOC(=O)C1=C(N)Oc2cc(C)n(C)c(=O)c2C1c1cccnc1 +CCS(=O)c1ccccc1C(=O)Nc1ccc2c(c1)COC2 +CC(C)C(NC(C(N)=O)c1ccccc1)c1ccccc1 +Cc1ccc(NC(=O)c2ccc(N3CC(C)OC(C)C3)nc2)c(C)c1 +CC1(C)Cc2c(C#N)c(N)n(-c3ccccc3)c(=O)c2CO1 +Cc1cc(CN(C)S(=O)(=O)c2cnn(C)c2)no1 +O=C(CN1CCc2ccccc21)NCC1Cc2ccccc2O1 +COCC(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +Cc1nc2ccccc2nc1Cn1ccc2ccccc2c1=O +COc1ccc(CCC(=O)N2CCN(CCC(N)=O)CC2)cc1 +CN(C)c1cccc(C(=O)NCCNC(=O)c2cccnc2)c1 +COc1ccc(C#N)cc1CNc1ccn(-c2ncccc2Cl)n1 +COC(=O)C1(c2ccccc2)CCN(C2CCOC2=O)CC1 +Cc1nc(CC(=O)N(C)Cc2nc3ccccc3s2)cs1 +Cc1ncsc1C(=O)NCCN1CCN(c2ccc(F)cc2)CC1 +COc1cc(C2NC(=O)c3oc4ccc(C)cc4c(=O)c32)ccc1O +CC(C)COc1ccc(C(=O)Nc2ccn(C)n2)cc1 +CCOc1ccc2nc(NC(=O)C3CC=CC3)sc2c1 +CCN(CCO)C(=O)Nc1ccc(C(=O)NC2CCCC2)cc1 +C#CCNC(=O)CSc1nnc(-c2ccc(C(C)(C)C)cc2)o1 +CS(=O)(=O)N1CCCc2cc(OC(F)(F)F)ccc21 +O=C(CCn1ccc2ccccc21)NCc1ccc2c(c1)OCO2 +COc1cc2cc(C(=O)N3CCCC3)[nH]c2c(OC)c1OC +Cc1c(O)cccc1C(=O)N1CCCC2(CCC(=O)N(CCO)C2)C1 +Nc1c(C(=O)N2CCOCC2)cnn1-c1ccccn1 +O=C(Nc1ccc(-c2csnn2)cc1)c1cccs1 +COc1ccc(C(CNCc2c(C)nn(C)c2C)N2CCCC2)cc1 +Cc1ccc(CC(NC(=O)C2CCCOC2)c2ccccn2)cc1 +O=C(NCCc1ccccc1F)C1CC(=O)N(CC(F)(F)F)C1 +CC(C)(CO)CNC(=O)c1cccc(Cl)c1N +NC(=O)C1CN(C(=O)NCC2CCCc3ccccc32)CCO1 +CC1CCCC(NC(=O)COC(=O)c2ccc(O)cc2O)C1C +CC(C)(C)OC(=O)N1CCN(c2nc3ccccc3c(=O)[nH]2)CC1 +C=CCNC(=O)C1CC(=O)N(c2cc(C)cc(C)c2)C1 +Cn1cc(C(=O)Nc2ccc3c(C(F)(F)F)cc(=O)oc3c2)cn1 +CC(NC(=O)OC(C)(C)C)c1nnc(SCc2ccccc2)o1 +NC(=O)c1ccc(COc2cccc3cccnc23)cc1 +COCCS(=O)(=O)N(Cc1ccsc1)c1cccnc1 +O=C(COC(=O)c1ccco1)Nc1ccc(Br)cc1 +O=C(CSc1ccccc1Cl)Nc1nnc(C2CCCO2)o1 +CN(Cc1nc2ccccc2[nH]1)C(=O)NCc1ccc2c(c1)OCO2 +CN1CCN(C(=O)CSc2ccccc2N)CC1 +Cc1ncc(CN2CCCN(C(=O)c3ccc(Cl)cc3)CC2)s1 +CCCC(=O)N1CCc2ccc(C(O)CC(C)C)cc2C1 +CCn1nc(C)c(CCNC(=O)Nc2ccc(C)c(C)c2)c1C +Cc1cc(C(=O)NCc2ccccc2CN2CC(C)OC(C)C2)on1 +N#CC(c1ccc(Br)cc1)N1CCOC1=O +COCc1cc(=O)[nH]c(N2CCN(c3ccccc3OC)CC2)n1 +OCCN(Cc1ccccc1)CC(O)c1cc(F)ccc1F +C=CCNc1ncnc(Nc2ccc(Br)cn2)c1N +Cc1c(C(=O)Nc2ccc3[nH]ncc3c2)nc2cc(Cl)ccn12 +CCc1nnc(C(C)N2CC(C)OC(c3ccccc3)C2)o1 +Cc1cc(C)nc(C(C#N)C(=O)CCCc2ccc(Cl)cc2)n1 +O=C(CCNS(=O)(=O)c1ccccc1F)NCc1ccccc1 +CN1CC(C(=O)N(C)Cc2cc(-c3ccccc3)no2)NC1=O +COc1ccc(C(N)=O)cc1S(=O)(=O)N1CCCc2ccccc21 +COc1cccc(CCC(=O)N=c2[nH]nc3cc(C)ccn23)c1 +CC(C)(C)c1ccc(CNC(=O)c2cccc(OCC(N)=O)c2)cc1 +CCCCNC(=O)C1CCCN(S(=O)(=O)N2CCC(C)CC2)C1 +CNS(=O)(=O)c1cc(C(=O)Nc2ccccc2C)ccc1OC +COc1cccc(N2CC(C)Cn3c2nc2c3c(=O)[nH]c(=O)n2C)c1 +OC(CNCc1csc(-c2ncccn2)n1)c1ccc(F)cc1 +O=C(Cn1c(=O)[nH]c2ccccc21)NCCc1cccc(F)c1 +CCC1COCCN1Cc1cccc(OCCCC#N)c1 +NC(=O)Cn1c(CO)cnc1SCc1cccc(Cl)c1 +COc1cccc(CC(=O)Nc2ccccc2C)c1 +CC(=O)NC(C(=O)Nc1ccc(N2CCCC2=O)cc1)C(C)C +C#CCN(Cc1ccc(F)cc1)Cc1nc(-c2ccsc2)no1 +O=C(NC1C=CC(CO)C1)NC(Cc1ccccc1)C(F)(F)F +O=C(Nc1ccc(OC(=O)C2Cc3cc(F)ccc3O2)cc1)C1CC1 +CCOc1ncccc1Cn1ccnc1-c1ccccn1 +COc1ccc(CC(=O)N2CCC(C(N)=O)CC2)cc1OC +COc1ccc(CCN2CCN(C(=O)C(C)n3cncn3)CC2)cc1 +Cc1c(C(=O)Cn2cnc3ccccc3c2=O)c2ccccc2n1C +CS(=O)(=O)NC1CCN(Cc2cnc3ncccn23)C1 +Cn1c(=O)[nH]cc(CC(=O)N2CCC(c3ccncc3)CC2)c1=O +CN(C)c1nnc(CCc2ccc(F)c(N)c2)o1 +CC(C)c1ccc(C=CCC(=O)NCc2ncn(C)n2)cc1 +COc1ccccc1-c1noc(-c2c[nH]c3ccccc3c2=O)n1 +COc1nc(N2CCC3(CCCN(C)C3=O)C2)ncc1F +CNCC(=O)c1cc2ccc(Br)cc2s1 +Cc1noc(C)c1CN(C)C(=O)Nc1cnc2c(c1)c(C)nn2C +O=C(C1CCCC1)N(CCc1cscn1)Cc1ccncc1 +Cn1cnc(CNC(=O)Nc2cc(C(F)(F)F)ccc2F)n1 +Cc1ccc(CN2CC(c3nc(-c4cccs4)no3)C2)o1 +COc1ncccc1CNC(=O)c1ccnc(OCc2ccccc2)c1 +N#Cc1ccccc1CN1CCN(C(=O)c2ccccc2)CC1 +Cc1c(C(C)(C)O)cnn1-c1cccc(C(F)(F)F)c1 +CC(C)C(=O)Nc1nn(C)c2c1C(C)CC(=O)N2 +COC(=O)N1CCN(Cc2nnnn2C2CC2)CC1 +COCCn1ccc(NC(=O)Nc2c(C)nn(C)c2OC)n1 +Cc1nonc1NC(=O)c1cc2ccccc2oc1=O +CC(C)CCn1nc(-c2cccs2)cc(CC#N)c1=O +CCNC(=O)CN(CC)C(=O)C(C)Oc1ccc(C#N)cc1 +COc1ccc(C(=O)N2CCC3(CCCN(C)C3=O)C2)o1 +C#CCOc1cc(F)ccc1NC(=O)CN(C)C(=O)OCC +CC(C)(C)CC(=O)Nc1ccccc1N1CCOCC1 +Cc1cccc(-c2cnc(CNCc3ccc4c(c3)OCO4)s2)n1 +CC(C)C(=O)N1CCC(c2nn3c(C4CCCO4)nnc3s2)CC1 +Cc1cc(C(=O)NC(C#N)C(C)(C)C)ccc1N1CCCS1(=O)=O +Cc1ccc(-n2ncc3c2NC(=O)CC3c2cccc(F)c2)cc1 +C=CCNC(=O)c1ccc(NC(=O)c2cnn(C(C)(C)C)c2)cc1 +COc1cc(CN2CCn3c(nn(C)c3=O)C2)ccc1SC +O=C(NCc1ccccc1)C1CCCN1C(=O)C1CCCCC1 +O=C(NCC#CCOc1ccc(F)cc1F)c1ccncc1 +COC(=O)c1ccc(C(=O)Nc2ncc(C)s2)cn1 +COc1ccc(CC(=O)Nc2nnc(Cc3ccccc3)o2)cc1 +COc1ccc(NC(=O)c2ccccc2NCc2noc(C)n2)cc1 +CCSc1nnc(NC(=O)CC2CCCC2)s1 +O=c1oc2ccccc2cc1-c1csc(NCc2ccco2)n1 +Cc1c(C)c2ccc(OCC(=O)N(C)C)c(C)c2oc1=O +COC(=O)c1ccccc1NC(=O)c1c(Cl)cnn1C +O=C1CN(C(=O)CSc2n[nH]c(C=Cc3ccccc3)n2)CCN1 +Nc1nccnc1C(=O)OCCOc1cccc(Cl)c1 +CC(=O)Nc1ccc(SC(C)C(=O)Nc2ncccc2C)cc1 +O=C(c1cc(Cl)ccn1)N1CCC2(CCOC2)C1 +COc1ccc(-c2nnc(NC(=O)COc3ccccc3)o2)cc1 +Clc1ccc(OCCc2nc3c(s2)CCN3)cc1 +Cc1ccnc(N2CCCC(C(=O)Nc3c(C)cccc3C)C2)n1 +CCC(C)C(C)NC(=O)c1ccc2c(=O)n(C)c(=O)n(C)c2n1 +CCn1nc(C)cc1C(=O)NCC(=O)NC1CC1 +COc1c(Cl)cccc1NC(=O)CCNC(=O)C(C)(C)C +N#Cc1cccc(NC(=O)CS(=O)(=O)c2ccc(F)cc2)c1 +O=C(Nc1cccc(Cl)c1)Nc1ccc2cn[nH]c2c1 +CNC(=O)NCC(=O)Nc1nc2ccccc2s1 +CCCOc1nc(COC)nc(NC2CCCCCC2)c1N +Fc1ccc(OCc2nccc(-c3ccc(-n4cncn4)cc3)n2)cc1 +Cc1ccc(C(=O)N(C)CC(=O)N2CCOCC2)cc1F +Cc1ccc(NC(=O)CCCc2nc3ccccc3c(=O)[nH]2)cc1C +O=C(CCCNC(=O)c1ccccc1)NCc1cscn1 +Cc1ccc(Cn2nnc3cc(C(=O)Nc4cc(C)on4)ccc32)cc1 +O=C(CNc1cccc(C(F)(F)F)c1)N1CCOCC1 +Cc1noc(C)c1CN(C)C(=O)c1c[nH]nc1-c1ccccc1 +COc1cccc(OCC(=O)Nc2cccc(Cn3cccn3)c2)c1 +CCCNC(=O)N1CCN(c2nc3cccnc3n(CC)c2=O)CC1 +O=C(NC1CC1)c1nc(Cn2c(=O)oc3ccccc32)no1 +COc1ccccc1-n1c(SCc2cccnc2)nc2cccnc21 +Cc1cc(CN2CC(c3ccccc3C)CC2C)no1 +O=C(Cc1csc(N2CCCC2=O)n1)Nc1ccc(F)c(F)c1 +Cc1cc(CSc2ccccc2C(=O)NCC(C)(C)C(N)=O)on1 +NC(=O)c1ccc(Br)c2ccccc12 +CCC(C)NC(=O)C1CC(=O)N(Cc2ccco2)C1 +COc1cccc(C(=O)N(Cc2ccncc2)Cc2cccnc2)c1 +CCCn1cc(NCc2cc(-c3ccccc3)[nH]n2)cn1 +CCC(CC)CC(=O)Nc1cccc(Cl)c1C(N)=O +O=C(CSc1nnc2n1CCCCC2)c1ccc2c(c1)CCO2 +Nc1cc(C(=O)CNc2ccc(F)c(Cl)c2)ccc1F +Cc1ccc(C)c(OCCCC(=O)Nc2cccc(N)c2)c1 +Cc1cc2nc(C3CCC3)n(CCCC#N)c2cc1C +CC1CCCN(S(=O)(=O)c2nnc(NC(=O)C(C)C)s2)C1 +COc1ccc(CNC(=O)N2CCN(C(=O)CCC(C)C)CC2)cc1 +CCNC(=O)CSc1nc(N)nn1-c1ccccc1 +Cc1cc(C)c(C#N)c(SCC(=O)NC2CCCCNC2=O)n1 +Cn1ncnc1NC(=O)C1CCCN(C(=O)C2CC2)C1 +CC(=O)N(CCc1ccccc1)CC(=O)Oc1cc(C)ccc1C +O=C(Nc1cc(F)ccc1Cl)c1ccccc1-n1cnnn1 +CNC(=O)c1cccc(CNc2cccc(Cl)c2OC)c1 +Cc1ccc(-c2cc(C(=O)Nc3ccc4c(c3)OCCCO4)[nH]n2)cc1 +CCOc1ccc(NC(=O)C2CC2(Cl)Cl)cc1 +CC(Cc1cccs1)NC(=O)CCS(=O)(=O)c1ccccc1 +CCc1cc2c(=O)n(Cc3cc(OC)ccc3OC)cnc2s1 +Cc1ccc(C(=O)N2CCOCC2c2ccccc2)c(C)n1 +COCCN(Cc1ccco1)C(=O)Nc1cccc(C)c1 +CCc1cc(Cn2cc(N)ccc2=O)ccc1OC +COc1cccc(C(=O)NCCNC(=O)c2c[nH]c3ccccc23)c1 +COc1cc(C2NCCc3cc(Cl)ccc32)ccn1 +CS(=O)c1ccc(C(=O)N(Cc2ccc(F)cc2)C2CC2)cc1 +COC(=O)C(NC(=O)c1cc(=O)c2ccccc2o1)C(C)C +COC(=O)C(C)(C)CNC(=O)Nc1cc(-c2ncco2)ccc1C +CCOC(=O)CNC(=O)Cc1cccc(OC)c1 +COc1cccc(OC)c1CNc1ccc(F)cn1 +COc1cc(CNn2nnnc2N)ccc1OCc1cccs1 +c1ccc(OCCc2nc3cc4c(cc3[nH]2)OCO4)cc1 +CCN(CC)c1nc2c(c(=O)[nH]c(=O)n2C)n1CCO +CCOc1ccc(NC(=O)C2CCCCN2C(=O)CC)cc1F +CC(C)c1nc(Sc2nnnn2C)c2ccccc2n1 +CCCC1CN(C(=O)c2cc(C)n(-c3ccccc3)n2)CCO1 +Cc1cccc(NC(=O)NCc2c(C)nn(C)c2C)n1 +CCn1c(CSc2ncnc3nc[nH]c23)nc2c(F)cccc21 +COc1ccc(C(C)NC(=O)CCn2c(C)csc2=O)cc1F +Cc1cc(C)n(C(C)C(=O)NCc2nc(-c3cccc(C#N)c3)c[nH]2)n1 +COc1cc(CNC(=O)CC(C)c2ccc(F)cc2)ccc1O +Cc1cc2occ(CC(=O)N3C(C)COCC3C)c2cc1C +Cc1ccc(C)c(CC(=O)OCC(=O)N2CCOCC2)c1 +CCc1ccc(C2COCCN2Cc2cn(C)nc2C)o1 +OCc1c(Cl)cccc1N(Cc1ccco1)C1CC1 +CC(C)NS(=O)(=O)c1cc(C(=O)NC2CC2)ccc1F +CCC(NCc1ccccc1)C(O)c1cccc(OC)c1 +CC1Cc2ccccc2N(C(=O)c2ccc(F)nc2)C1 +CC(=O)Nc1ccc(F)c(NC(=O)c2cccc(Cl)c2Cl)c1 +COCc1cc(N2CCC(NC(=O)C(C)C)CC2)nc(C(C)(C)C)n1 +O=C(Nc1ccc(F)cc1)c1csc(Nc2cccnc2)n1 +Cc1ccc(C(=O)N2CCC3(CC(Oc4cccnc4)CO3)C2)cn1 +O=C(c1cnccn1)N1CC2CN(S(=O)(=O)C3CC3)CC2C1 +Cc1ccccc1CNC(=O)Cn1cnc2c(cnn2C)c1=O +O=C1Nc2ccc(F)cc2C12CC(O)=Nc1c2cnn1-c1ccccc1 +CC(=O)N(C)Cc1ccccc1NC(=O)CN(C)C(=O)OC(C)(C)C +Cc1ccc(C(=O)CCC(=O)Oc2cccc(S(C)(=O)=O)c2)cc1 +NC(=O)c1cc(-c2cccnc2)nc2c1cnn2Cc1ccco1 +O=C(NCCc1cccc(Cl)c1)c1cc2ccccn2n1 +CC(C)(C)c1nc(COC(=O)c2ccc(S(N)(=O)=O)o2)no1 +COCc1cccc(NC(=O)CCn2ncc3cc(Cl)ccc32)c1 +CCOC(=O)COC(=O)c1cc2ccccc2oc1=O +Cc1cccc(C(=O)N2CC3CC(Cc4nc(C)no4)OC3C2)n1 +COC(=O)C1(Cc2cc(-c3ccc(C)cc3)no2)CCOCC1 +CC(=O)N1CCC(C(=O)NCc2cccc(COC(C)(C)C)c2)CC1 +O=C(Nc1ccc2oc(=O)ccc2c1)c1cccs1 +CCN(C(=O)c1cnc(-c2ccco2)nc1N)c1ccccc1 +CCCCCNc1cc2c(cc1Cl)NC(=O)CO2 +Cc1cccc(C)c1OCC(=O)N(C)CC1COc2ccccc2O1 +CC1COCC(C)N1Cc1coc(-c2ccc(F)c(F)c2)n1 +Cc1cc(C)cc(Nc2ncnc(NCCN3CCOCC3)c2N)c1 +Cc1nc(Nc2nncs2)cc(C2CCCN2c2ncccn2)n1 +C=CCOCC(O)Cn1c(NC)nc2c1c(=O)[nH]c(=O)n2C +Cc1noc(CCC(=O)N(Cc2ccc(C)s2)C(C)C)n1 +CN(C(=O)Cn1ccccc1=O)C1CCc2ccccc21 +COc1ccc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)cc1 +Cc1ccc(Nc2ncnc(OC(C)C)c2N)cc1C +O=C(CCn1ncc(=O)c2ccccc21)Oc1cccc(F)c1 +CCCCCc1nnc(NC(=O)c2ccncc2)s1 +CC(C)c1nnc2n1CCN(C(C)C(=O)NCC1CCCO1)C2 +O=C(C1CCCN1S(=O)(=O)c1ccc(F)cc1)N1CCOCC1 +Cc1ccccc1CCNC(=O)CSc1nnnn1C +Cc1csc(NC(=O)c2nccc3c(N)ccc(C)c23)n1 +CC(=O)n1c2ccc(F)cc2c2nc3ccccc3nc21 +CCNC(=O)c1cccc(CNC(=O)c2scnc2C)c1 +CCC(=O)Nc1ccc(NC(=O)c2ccccc2)c(O)c1 +Cc1ccc(C(=O)c2ccccc2C(=O)N2CCOCC2)cc1C +O=C(NCC1CC=CCC1)Nc1nnc(C(F)(F)F)s1 +O=C(NCc1ccc(O)cc1)c1ccc(N2CCOCC2)nc1 +Cc1ccc(NC(=O)COc2ccccn2)c(Br)c1 +COCC(=O)Nc1cccc(C(=O)N2CCc3sccc3C2)c1C +CC(CO)NC(=O)Nc1ccc(=O)n(Cc2ccccc2Cl)c1 +CC(NS(=O)(=O)CC1CCOCC1)c1cc(F)c(F)c(F)c1 +COCc1cccc(NC(=O)Cc2cccc(OCC#N)c2)c1 +CCc1onc(C)c1NC(=O)NC(C)C1COc2ccccc21 +Cc1nc(C)n(CC2CN(C(C)c3cccnc3)CCO2)n1 +O=C(NCc1ccccc1F)c1ccc2c(c1)nc1n2CCCCC1 +CCC(CC1CCCC1)C(=O)OCc1nc(C)no1 +C=C(C)CN(CC)C(=O)c1cccnc1OCC(F)F +Cc1noc(C)c1CC(=O)Oc1ccc(C(F)(F)F)cc1 +CC(=O)c1ccc(C(=O)Nc2cccc(Cl)c2)cc1 +CCN(CC(=O)OC)C(=O)CSc1cccs1 +COCCNC(=O)N(C)CCN(C)c1ccccc1 +Cc1ccc(F)cc1NC(=O)Cc1cn2ccccc2n1 +O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)Nc1nccs1 +COCCOCCNC(=O)Nc1cccc2c1CCCC2 +Cc1sc2c(c1C)C(=O)NC(c1cccnc1)N2 +Cc1nn(C)c2ncc(NC(=O)c3ccccc3)cc12 +Cc1ccc(C(C)Nc2ncnc3c2cnn3C)o1 +COc1cccc(C(=O)Nc2nnc(-c3cc(C)nn3C)o2)c1OC +CNC(=O)C1(NS(=O)(=O)N(C)C)CCCCC1 +Cc1ccccc1NC(=O)C(C)n1nc(C)n2cncc2c1=O +CC(CNC(=O)COC(=O)c1ccco1)c1ccccc1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)c2cc(C)n[nH]2)c1 +COc1ccc(OC(C)C(=O)N2CCNC(=O)CC2)cc1 +CC1CCCC(NC(=O)Nc2cccc(NC(=O)C3CC3)c2)C1 +O=C(NCc1cn[nH]n1)c1csc(-c2cnccn2)n1 +Cc1ccc(C)c(NC(=O)C(C)Oc2cccc(N)c2)c1 +CC(CC1CCCC1)C(=O)Nc1cccnc1-n1cncn1 +CC(CC1CCCC1)C(=O)NCCC(=O)Nc1ccccc1 +CCC(Oc1cccc(C)c1)c1nc(N)nc(C)c1C(=O)N(C)C +CC(C)NS(=O)(=O)C1CCOCC1Cc1cccc(Cl)c1 +C#CCn1c(CCNC(=O)c2ccc(C)cc2)nc2ccccc21 +CCCOC1CCCN(C(=O)CCC(=O)c2cccs2)CC1 +CCc1nc(N)nc(N2CCC(c3ncon3)CC2)c1C +CC1(CNC(=O)c2ccc(OCC(F)F)nc2)COC1 +Cc1cc(CN(C)C(=O)C2CCCN(S(C)(=O)=O)C2)no1 +COc1cccc(C(=O)NCc2nc3ccc(F)cc3[nH]2)c1F +N#CCc1ccc(NC(=O)Cn2c(=O)[nH]c3ccccc32)cc1 +CC(C)C(=O)N1CCN(C(=O)c2n[nH]c3c(Cl)cccc23)CC1 +O=C(NCc1cc(-c2ccccn2)n(C2CCCC2)n1)c1cccnc1 +Cc1ccc(C(N)=O)cc1NC(=O)c1cc(C)c(C)s1 +CCCNc1ncnc2c1cnn2CCNC(=O)C(C)(C)C +Cc1noc(C)c1S(=O)(=O)Nc1ccc(F)c(F)c1 +CC(Oc1ccccc1Cl)C(=O)OCC1CC(=O)N(C2CC2)C1 +CC(NC(=O)Nc1ncn(Cc2ccc(Cl)cc2)n1)C1CCCO1 +Cn1ncc(C(=O)N2CCN(CCSc3ccccc3)CC2)c1N +Cc1ccc2ncn(CC(=O)N(C)C3CC3)c(=O)c2c1 +O=C(Cc1ccc(-n2cccn2)cc1)N1CCc2ccccc21 +C=C(C)CN(CC)C(=O)C(C)N1CCN(C(=O)COC)CC1 +CCOCCCNC(=O)c1ccc2c(=O)n3c(nc2c1)CCCC3 +O=C(c1scnc1C1CC1)N1CCOC2(CCCC2)C1 +CC(=O)c1ccc(NCC(=O)Nc2ccccc2OC(F)F)cc1 +CC(C)CCC(=O)N(C)Cc1csc(C#CCO)c1 +CCOc1ccc(C(=O)NCc2cccc(C)c2)cc1 +O=C(NCc1cc[nH]n1)C12CC3CC(CC(C3)C1)C2 +CCOC(=O)CC(C)CNC(=O)C1CCN(C(C)=O)CC1 +CCOC(=O)N1CCC(NC(=O)Nc2ccc(OC)c(F)c2)CC1 +CN(CCCNc1ncnc2c1oc1ccccc12)CC(F)(F)F +CCOc1ccc(-c2nc(-c3ccnc(OC)c3)no2)cc1OC +CC(NC(=O)c1ccc(-n2ccnn2)cc1)c1ccccc1 +Cc1cccc(NC(=O)c2ccc(N3CCCC3=O)cc2)c1 +CC(=O)NCc1ccc(S(=O)(=O)NCC2CC2C)s1 +COc1ccc(CCNC(=O)c2cc(=O)[nH]c3ccccc23)cc1 +COC(=O)c1sc2cccc(F)c2c1CNC(=O)Cc1ccon1 +O=C(NCCOc1cccc(F)c1)NCCc1ccccc1F +CCc1c(C(=O)N(C)CCC#N)cnn1-c1ccccn1 +O=C1Cc2cc(S(=O)(=O)N3CCOC4CCCCC43)ccc2N1 +CCN(C(=O)c1ccc(C)nc1N)c1ccccc1 +CCCn1c(-c2cc(C)ccc2OC)ccc(N)c1=O +N#CCCN(CCC#N)C(=O)C1CC1c1ccc(Cl)cc1 +COc1cccc(CNC(=O)NC(C)(C)c2cccc(C)c2)n1 +Cc1sc(NC(=O)c2cccc(CC#N)c2)c(C(N)=O)c1C +Cc1ccc(C(=O)NC2CC2)cc1NCC(=O)N(C)C +COC(=O)c1ccccc1C1NC(=O)c2ccccc2N1 +CC(=O)c1ccc(-c2ccc3c(c2)OCCO3)s1 +CC(=O)NC(C)C(=O)N1CCN(C(=O)N(C)C)CC1 +CC(=O)NCc1ccc(-c2csc(Nc3cccnc3)n2)s1 +CCCC(=O)Nc1nnc(S(=O)(=O)N(CC)CC)s1 +O=C(Nc1nnc(CCc2ccccc2)s1)c1ccccc1F +O=C(c1ccc(Cl)cc1)N1CC(c2nc3ccccc3[nH]2)C1 +Cc1cc2c(cc1NC(=O)c1cccc(Cl)c1)n(C)c(=O)n2C +COc1ccc(Br)cc1-c1cc(N)nn1C +N#Cc1ccc(Cn2c(=O)ccc3cc(N)ccc32)cc1 +COc1cccnc1NC(=O)c1cc(C2CC2)n(C(C)(C)C)n1 +Cn1nc(C(=O)N2CCCCCC2)c(=O)c2ccccc21 +O=C(c1c(F)cccc1Cl)N(Cc1ccsc1)C1CC1 +O=C(C1CC1)N1CCN(Cc2ccc(Cl)cc2Cl)CC1 +COCC1CCCC12CN(CCc1ccccc1)CCO2 +CNC(=O)C1CN(C(C)C)CCN1C(=O)c1cccnc1N +CCOC(=O)c1cccc(NC(=O)c2ccc3c(c2)OCCO3)c1 +CC(C)c1csc(NC(=O)CNC(=O)Cc2ccccc2)n1 +CCC(=O)N1CCc2ccc(NC(=O)Nc3ccccc3)cc2C1 +COc1ccc(C(=O)CCC(=O)NC(C)(C)C)cc1N +Cc1nn(C)c(C)c1CCC(=O)Nc1nccs1 +Cc1c(Cl)cccc1NC(=O)c1nn(C)c2ccc(F)cc2c1=O +O=C(COc1ccc2c(c1)CCC2)NCc1cn[nH]c1 +CCNC(=O)CNC(=O)CNC(=O)c1ccccc1 +Cc1ccc(-n2ccnc2)c(C(=O)Nc2ccc(F)cn2)c1 +O=C(CCC(=O)N1CCc2sccc2C1)Oc1ccccc1 +CCN(Cc1cccs1)C(=O)CCc1cccs1 +CC(=O)N1CCCC(C(=O)N2CC(Oc3cccc(C)c3)C2)C1 +CCOC(=O)CNc1c(N)n(CC)c(=O)[nH]c1=O +CC(=O)Nc1ccc(CC(=O)N(c2ccccc2)C(C)C)cc1 +O=C(CN1C(=O)C2CCCN2c2ncccc21)NC1CCCCC1 +CC1CC(C)CN(C(=O)C2CCC(=O)N2Cc2ccco2)C1 +Cc1ccc(NC(=O)CNC(=O)Cc2ccc[nH]2)c(Cl)c1 +Cc1cc(C)n2ncc(C(=O)N3CCn4nc(C)nc4C3)c2n1 +CCOC(=O)Nc1ccc(NC(=O)NC(C)(C)C)cc1 +O=S1(=O)NCNc2cc(C(F)(F)F)ccc21 +Cc1ccc(C(=O)OCC(=O)Nc2nccs2)cc1C +COc1ccc(C(O)CCNc2ccccc2F)cc1 +Cn1c(C(=O)N2CCc3nc[nH]c(=O)c3CC2)cc(=O)n(C)c1=O +c1cnc(N2CCC(c3n[nH]c4ncccc34)C2)nc1 +N#Cc1ccc(NC(=O)Cc2csc(-c3ccsc3)n2)cc1 +COc1ccc2c(c1)CC(C(=O)NCCCN1CCCC1=O)CO2 +CN(C(=O)CCCc1cc(F)ccc1F)c1nc2ccccc2o1 +CCCn1c(NC(=O)C2CC2C)nc2ccccc21 +COC(=O)c1cc(-n2cnc(C#N)n2)c(F)cc1N +CCC1CCC(NC(=O)c2ccc(-n3cncn3)nc2)CC1 +COc1cccc(NC(=O)c2cccc(NS(C)(=O)=O)c2)c1 +O=C1CN(C(=O)Cc2ccc(-n3cccc3)cc2)CCN1 +CC(=O)Nc1ccc(NCc2noc(C)n2)c(Cl)c1 +Cc1ccc(S(N)(=O)=O)cc1C(=O)NCc1ccc2c(c1)OCO2 +Cc1noc(C)c1C(C)CNC(=O)c1cnn(-c2ccncc2)c1C +O=C(c1ccc(OCC2CC2)nc1)N1CCc2cc(F)ccc2C1 +Cc1c(F)cc(C(N)=O)cc1NC(=O)c1cnc(C2CCCO2)s1 +COc1cccc(OC2CN(C(=O)c3csc(C(C)=O)c3)C2)c1 +Cn1ccc2c(OCC(=O)NCc3ccc(F)cc3)cccc2c1=O +CCOc1cc(F)ccc1NC(=O)c1cc(OC)c(OC)cc1C +CCc1c(C)sc(NC(=O)c2cnn(CC)c2)c1C#N +CCC(=O)NC(Nc1ccc(O)cc1)(C(F)(F)F)C(F)(F)F +Cc1ccn2c(=NC(=O)c3ccc(Br)cc3F)[nH]nc2c1 +O=C(NCCCNc1cccc(F)c1)c1ccc[nH]1 +Cc1ccc2oc(C3CCN(C(=O)c4cccnc4)C3)nc2c1 +O=C1CC(C(O)c2cccs2)CN1C1CCCCC1 +CCC(=O)Nc1ccc(C)c(NCc2nnc(CC)o2)c1 +CC(C)N(C)C(=O)NCC(c1ccccc1Cl)N1CCOCC1 +CCOC(=O)N1CCN(C(=O)c2c[nH]c3cccc(F)c23)CC1 +COc1cc(C)c(C)cc1C(=O)N1CCN(CCO)CC1 +CC(NC(=O)Cc1cnn(-c2ccccc2)c1)C1CC1 +O=C(CNC(=O)C1CCCO1)Nc1ccc(Cl)cc1 +COc1cc(C(C)=O)ccc1OCc1cc(=O)n2c(C)cccc2n1 +COc1ccc(OC)c(-c2cc(C#N)nn2-c2ncccn2)c1 +CCOC(=O)c1cnn(S(C)(=O)=O)c1C(F)(F)F +COc1ccc(-c2nnc(COc3cccc(N)c3)o2)cc1 +Cc1cccc(C(O)CN2CCc3ccccc32)c1 +O=c1[nH]c(Nc2cccc(Cl)c2)nc2c1CCC2 +O=S(=O)(NCC1(c2ccc(F)cc2)CC1)N1CCCCCC1 +Cc1nnc2sc(-c3cccc(NC(=O)c4ccccc4)c3)nn12 +COc1ccc(CC(=O)Nc2cccc(-n3cnnc3)c2)cc1OC +Cc1c(C(=O)N2C(C)COCC2C)cnn1-c1ccncc1 +Cc1noc(CNC(=O)C(c2ccccc2)c2ccccc2)n1 +O=C(CCC1CCCO1)Nc1ccc(Cl)cn1 +CCNC(=O)CN1CCN(C(C)c2nnc(-c3cccs3)o2)CC1 +COc1ccc(CNC(=O)c2[nH]c3c(c2C)C(=O)CCC3)cn1 +CC(C)N1CCN(C(=O)C2CCCN2C(=O)c2cccs2)CC1 +CN(CC(O)C1CC1)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +CC(Oc1ccc2ccc(=O)oc2c1)C(=O)Nc1cccc(C#N)c1 +Cc1ccc(C(=O)NCc2ccc(-c3ccn[nH]3)cc2)c(=O)[nH]1 +O=C(NCCOC(=O)c1cc2ccccc2s1)c1ccncc1 +O=C1CCC(C(=O)Nc2cc(F)cc(N3CCCC3)c2)N1 +Cc1ccc(C)c(OCC(O)CN2CCN(C(=O)C3CC3)CC2)c1C +CN1CC(NC(=O)c2cn(C)nc2C(C)(C)C)CCC1=O +NC(=O)c1cnc(CC2COCCN(C(=O)Cn3cccn3)C2)cn1 +CCCCS(=O)(=O)NC(CC)C(=O)N1CCNCC1 +CC(C)(C)c1nc(CNC(=O)C2COc3ccc(F)cc3C2)no1 +COc1ccc(OCCNC(=O)NCc2ccccn2)cc1 +C=CCNC(=O)c1ccc(C)c(S(=O)(=O)N2CCCCC2)c1 +CC(CO)C(C)NC(=O)Nc1cccc(Br)c1 +NC(=O)CCN(Cc1ccccc1)C(=O)NCc1ccccn1 +Nc1ncn(CC(=O)Nc2ccc(F)cc2F)n1 +CCCn1cnc2c1c(=O)n(Cc1cc(C)no1)c(=O)n2C +COc1cc(C)c(Cl)c(C)c1-c1nn(C)c(C)c1N +Brc1ccc(NCCCN2CCOCC2)cc1 +Cn1c(C(=O)Nc2ccc(Cl)cn2)cc2c(F)cccc21 +NC(=O)Cc1ccc(NC(=O)CC(F)(F)F)cc1 +O=C(CCOc1ccc2c(c1)OCO2)NCCO +CCCC1CN(C(=O)Nc2cccc(C(=O)NC(C)(C)C)c2)CCO1 +CC(=O)Nc1cccc(NC(=O)c2sccc2C2CC2)c1 +CN(C)c1cccc(C(=O)NCC(O)c2ccccc2)c1 +CC(C)NC(=O)Cc1ccc(NS(=O)(=O)c2ccccc2)cc1 +CCc1nnc(-c2cc(NC(=O)c3cccc(F)c3)c(C)s2)o1 +Nc1c(-c2nnnn2-c2ccccc2)cnc2cc(Cl)ccc12 +C=CCn1c(CCNC(=O)c2ccc(F)cc2)nc2ccccc21 +Cc1noc(C)c1CN1CCN(C(=O)C(C)n2cncn2)CC1 +CSc1cccc(NCc2ccccc2C#N)c1 +CC(n1nnc2ccccc21)n1nnc2ccccc21 +CCn1nc(C(=O)N2CCCC(c3cc(=O)[nH]c(C)n3)C2)cc1C +O=C(NCc1ccccn1)Nc1ccc(Cl)c(C(F)(F)F)c1 +O=C(NCc1ccccc1)C1CC(=O)N(CCc2ccccc2)C1 +CNC(=O)C(NC)c1ccc(C2CCCCC2)cc1 +c1coc(C2CN(Cc3ccc(Oc4cnccn4)cc3)CCO2)c1 +COc1ccc(CNC(=O)C2(C#N)CCCC2)cc1 +Nc1nccnc1C(=O)Nc1ccc(-n2cccn2)cc1 +CCCC1CN(C(=O)CC2c3ccccc3C=CN2C(C)=O)CCO1 +Cc1occc1CN(C)S(=O)(=O)c1cccnc1 +Cc1ccc(C(=O)N(C)CCC(C)(C)O)cc1N1CCNC1=O +O=C(Nc1cc(-c2ccccc2)ns1)N1CCCC(CO)C1 +Cc1ccccc1-c1nnn(CC(=O)NCC2CCCO2)n1 +Cc1cccc2c(NC(CC(N)=O)C3CCOCC3)ncnc12 +CC(C)OCCC(=O)Nc1cc(F)c(F)c(F)c1 +CCOCC1CCCN(C(=O)C(NC(=O)OC)C(C)C)C1 +CCCNC(=O)NCC(C1CCOC1)N1CCOCC1 +COc1ccc(C(=O)NCCNC(=O)c2cc(C(C)=O)c[nH]2)cc1 +O=C(c1cnccn1)N1CCCCCC1c1ccco1 +CN(C)C(=O)CNC(=O)NCC#Cc1ccccc1 +O=C(COC(=O)c1cnn(-c2ccccc2)n1)NC1CCCCC1 +CCOc1cc(CNC(=O)C2CC3CCC2C3)ccc1OC(F)F +COc1cc(C)sc1C(=O)NCCS(=O)(=O)c1ccccc1 +CC(=O)c1ccc(OCC(=O)N2CCOc3ccc(F)cc32)cc1 +CCc1noc2nc(C)nc(NCc3ccc(Cl)cc3)c12 +CN(C)S(=O)(=O)c1ccccc1-c1cccc(O)c1 +O=C1CSc2ccccc2N1CC(=O)N1CCOC2CCCCC21 +CC(O)CN1CCN(C(=O)Cn2cccc(C(F)(F)F)c2=O)CC1 +Cc1ccc(-n2nnnc2CS(=O)(=O)c2ccccc2)cc1 +COc1ccc(OC)c(C(C)C(C#N)N2CCOCC2)c1 +CN(C)c1ncnc(NCc2ccccc2Cl)c1N +CCCn1ccc(C(=O)Nc2ccc(F)c(F)c2)n1 +COCCCn1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)n1 +CC(C)n1ncc2c(C(=O)NCC(N)=O)cc(-c3ccco3)nc21 +Cc1nnc(SC(C)c2ccccc2)n(N)c1=O +CC1CN(C(C)c2nc3ccccc3[nH]2)CC(C)O1 +Cc1nc(-c2ccco2)ccc1C(=O)N1CCn2c(C)nnc2C1 +CC(C)(CNC(=O)CCSc1ccccn1)c1ccncc1 +CC1CCC(NC(=O)Cn2ncc3ccsc3c2=O)CC1 +CCc1nc(CCNC(=O)N2CCC(c3nc[nH]n3)CC2)sc1C +O=C(Nn1cnc2ccccc2c1=O)C1CCCc2ccccc21 +COc1cccc(-c2nnc(NC(=O)c3cc4ccccc4o3)o2)c1 +Cc1ccc(CN2CCn3c(nnc3C(F)(F)F)C2)o1 +CC(CNC(=O)Cc1ccc[nH]1)c1ccc(F)c(F)c1 +c1cncc(-c2nc3c4c5c(sc4ncn3n2)CCCC5)c1 +CC(NC(=O)c1cn2cccnc2n1)c1ccc(F)c(F)c1 +COCc1nc(C)cc(NC(c2ccccc2)C2CCOCC2)n1 +CCS(=O)(=O)N(C)CCCc1ccc(OC)cc1 +COc1cc(C(=O)Cc2nc3ccccc3[nH]2)cc(OC)c1OC +COc1cc(C)c(C(C)NC(=O)NC(C)c2nncn2C)cc1OC +CC(C)NC(=O)C1CC2CN(Cc3ccccn3)CC1O2 +CCOc1ccc(NC(=O)C2CC3CCC2C3)cc1CO +Cc1cc2nc(C)n(CC(=O)Nc3ccccc3)c2cc1C +CCCc1nc(C(F)(F)F)c(C(=O)OCC)s1 +Cc1cc(CNS(=O)(=O)N2CCCCCC2)ccc1F +CC(C)C1C(=O)NCCN1Cc1cc(C(N)=O)cs1 +CC(=O)c1sc(NC(=O)CCc2cccc(Cl)c2)nc1C +COCCCNC(=O)Nc1ccccc1-n1nc(C)cc1C +CSc1ccc(NC(=O)C(C)Sc2nncn2C2CC2)cc1 +O=C(COCC1CCCO1)N1CCC(c2cccc(F)c2)C1 +CN(CC(O)C1CC1)c1nnc(Cc2ccccc2)s1 +O=c1[nH]cncc1Oc1ccc(Cl)c(Cl)c1 +C#CCC(OC(=O)c1ccc(N2CCNC2=O)cc1)c1ccccn1 +Nc1nonc1C(=O)N1CCCC1C(=O)NC1CC1 +O=C(Nc1cccc(F)c1)c1ccc(Cn2ccnc2)cc1 +CCCCn1c(SCC(=O)N2CCCCCC2)n[nH]c1=O +O=C1CCCN1Cc1nnc2n1CCN(C(=O)C1CCC1)CC2 +COC(=O)C(C)(C)NC(=O)c1cc(C(C)(C)C)nn1C +Cc1oc(-c2ccccc2)nc1C(=O)Nc1cnccc1-n1ccnc1 +O=C(CCC(=O)c1ccc(Cl)cc1)NCc1cccs1 +O=C1OCCCN1CCn1ccnc1-c1ccccn1 +CCN(Cc1cccc(F)c1)S(=O)(=O)c1ccccc1F +CCCc1nc(C(C)(C)NC(=O)c2sc(C)nc2C)no1 +CCCCN(C(=O)c1cc(Br)cn1C)C1CC1 +CC(CCCO)NC(=O)Nc1ccc2oc(C3CC3)nc2c1 +CN(c1cccc2ncccc12)S(=O)(=O)c1ccc(F)cc1F +Cc1cc(OCC(=O)Nc2cccc(-c3nnnn3C3CC3)c2)no1 +CCCc1nnc(NC(=O)c2cnc(N(C)C)nc2N)s1 +CS(=O)(=O)N1CCN(c2cccc(O)c2)CC1 +COC(=O)CC(NC(=O)c1cccnc1)c1ccc(OC)cc1 +CC(=O)N1CCc2nc(NC(=O)C3CCC3)sc2C1 +Cc1cc(S(=O)(=O)NCCC(O)C(C)(C)C)ccc1F +COCc1nc(C)cc(NCc2ccc(-c3ccn[nH]3)cc2)n1 +Cc1cccc(C)c1-n1nnnc1CS(=O)(=O)c1ccc(F)cc1 +CCc1ccc(-c2nccn2-c2ccc(OC)nc2)nc1 +Cc1cnc(CNC(=O)c2cccc(-c3cn[nH]c3)c2)cn1 +O=C(NC1CCN(C(=O)c2cccs2)CC1)c1ccc(F)cc1 +CCc1ccc2nc(CCn3c(=O)oc4ccccc43)[nH]c(=O)c2c1 +CC(C)CCNC(=O)NCc1noc(-c2ccsc2)n1 +CNC(=O)C1CCCCN1C(=O)c1ccc(OCC(F)F)nc1 +CC(=O)c1ccc(NC(=O)CCc2c(C)[nH]c3ncnn3c2=O)cc1 +COc1cccc(C(=O)Nc2cc(C)nn2C(C)(C)C)c1 +COc1cc(C(=O)N2CCCC(C(=O)c3nccn3C)C2)ccn1 +CCC(OC1CCCCC1)C(=O)N1c2ccccc2CC1C(N)=O +CC(C)n1nccc1NC(=O)c1ccn(-c2ccccc2Cl)n1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccc(F)c(F)c2F)cc1 +COC(=O)c1cc(CNC(=O)c2ccccn2)ccc1OC +CCOc1ccc(C#N)cc1NC(=O)NC(C)C(=O)NC(C)(C)C +CCOC(=O)Nc1cccc(NCc2nc(-c3ccco3)no2)c1C +O=C(Cn1c(=O)c2nncn2c2ncccc21)NC1CCCCC1 +O=C(NCCNc1ncccn1)c1sccc1SC(F)F +Cc1cc(Cl)cc2sc(NC(=O)c3ccno3)nc12 +COc1ccc(Cc2cnc(NC(=O)c3csnn3)s2)cc1 +COCCN(C)C(=O)NCCCN1CCCCCC1=O +COCc1cc(NC(=O)C(C)Cc2ccc(OC)cc2)ncn1 +CCn1c(C)cc(=O)c2cc(C(=O)Nc3cccc(C)n3)ccc21 +O=C(Nc1ccc(OC(F)F)cc1OC(F)F)N1CCOCC1 +Cc1cccc(C)c1N1CCN(S(=O)(=O)N2CCCCC2)CC1 +COc1ccc(NC(=O)c2ccc3c(c2)OCO3)cn1 +CCNC(=O)C1CCCN(c2ccc(-n3ccc(C)n3)nn2)C1 +CCNC(=O)N1CCOCC1c1noc(-c2ccccc2)n1 +CCC(O)(CC)CNC(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +CC(CN1CCOCC1)NS(=O)(=O)c1ccc(C#N)cc1 +CC1CCc2sc(C(=O)NCCN3CCOCC3)cc2C1 +CNC(=O)c1cc(C)ccc1NC(=O)COCc1ccccc1Cl +CCC(O)c1cnc2c(Cl)cc(Br)cn12 +CCC(C)OC(=O)CS(=O)(=O)c1ccc(C(C)=O)cc1 +CC(=O)C(C)n1c(C(C)NC(=O)c2ccccc2)nc2ccccc21 +Cc1c(N)ccc2nc(Cc3ccc(F)cc3)cn12 +CCN(CC1CCOC1)C(=O)c1cc(C2CC2)on1 +Cc1ccccc1Cn1c(CO)nc2cc(F)ccc21 +Cn1cc(-c2ccccc2NC(=O)Cc2ccccc2)cn1 +CC(=O)NCCNC(=O)NCC(=O)Nc1ccccc1 +CC1=C(C(=O)NC2CC(=O)N(CCc3ccccc3)C2)OCCO1 +O=C(Cc1cn2ccsc2n1)N1CCOCC1C1CC1 +Cc1ocnc1C(=O)Nc1ccc(-c2nnc(N(C)C)o2)cc1 +CCc1c(O)c(=O)ccn1Cc1ccc(S(N)(=O)=O)cc1 +CCOc1ccc(C#N)cc1NC(=O)NC1c2ccccc2CC1O +CSc1nc2nc(C)c(CC(=O)Nc3ncc(C)s3)c(C)n2n1 +O=C(Cc1ccc(O)cc1)NC(c1ccc(F)cc1)c1cccnc1 +O=c1[nH]c2ccccc2n1CCc1c[nH]c2ccccc12 +CN1CC(NC(=O)C2(c3cccs3)CCCC2)CC1=O +Cn1cc(C(=O)Nc2ccc(C#N)cc2)c(-c2cccs2)n1 +CC(=O)c1ccc2c(c1)N(CC(=O)OCC(C)C)CC(C)O2 +COCCNC(=O)c1ccc(CS(=O)(=O)c2ccc(C)cc2)o1 +CC(=O)c1ccc(S(=O)(=O)NCCOc2ccccc2F)cc1 +O=C(NC(c1nccs1)C1CC1)c1ccc(-n2ccnn2)cc1 +Cc1nc(C(=O)c2ccc3c(c2)OCCO3)cs1 +Cc1nn(CC(=O)Oc2ccc(C#N)cc2)c(C)c1Cl +Cc1cccc2c(=O)n(CCC(=O)OC3CCCCC3)cnc12 +N#Cc1ccc(C(=O)N2CCCC2c2nc(C3CC3)no2)cc1 +O=C(OCCN1CCCC1=O)c1ccc(F)c(F)c1 +CCn1c(=O)n(CC#N)c(=O)c2c3c(cnc21)C(=O)CC(C)(C)C3 +CCC(C)(C)NC(=O)CSc1ccc(OC)cc1 +Nc1ncccc1C(=O)NCCc1ccc(S(N)(=O)=O)cc1 +O=C(Cc1ccc(F)c(F)c1)NCc1nc(-c2ccncc2)no1 +CCn1c(N(C)Cc2ccccc2)nc2c1c(=O)n(C)c(=O)n2C +C=CCSc1ccccc1NCc1ccccn1 +CC(=O)Nc1ccc(Sc2ncnc3sc(C)c(C)c23)cc1 +O=c1cc(CN2CCCCCC2c2ccco2)[nH]c2ccnn12 +CCOCC(=O)NCc1csc(-c2ccccc2)n1 +CCNS(=O)(=O)c1ccc(Cl)c2ccccc12 +COC(=O)CCn1c(C#N)nc2ccc(F)c(F)c21 +O=C(c1csc(-c2nc[nH]n2)n1)N1CCCCCC1c1ccco1 +CN(CC(F)F)C(=O)NC1CC1c1cccc(Cl)c1 +CCCOC(=O)CN1CC(CC)Oc2ccc(N)cc21 +CCOc1ccc(F)c(C(=O)N2CC3OCCN(C)C3C2)c1F +CNC(=O)CN(c1ccc(Oc2ccccc2)cc1)S(C)(=O)=O +O=C(C1CC=CCC1)N1CCN(Cc2ccc(Cl)cc2)CC1 +CCC(NC(=O)c1cc(C(C)C)[nH]n1)c1ccccc1OC(F)F +CC1CN(C(=O)COc2ccc(Cl)cc2C(N)=O)CC(C)O1 +Cc1ccc(CNC(=O)N(C)Cc2cnn(C)c2)c(OC(C)(C)C)c1 +CC(C)CNC(=O)Nc1cccc(C#Cc2ccccn2)c1 +OC(CNCc1ccc2c(c1)OCO2)c1ccc(Cl)cc1 +O=C(Nc1nccs1)c1ccc(OCC2CC2)cc1 +CC(=O)c1ccc(-c2ccc3c(c2)CCN3C(C)=O)o1 +CS(=O)(=O)N=c1ccc(-c2cccc3ccsc23)c[nH]1 +CCCCOc1cc(S(N)(=O)=O)ccc1Cl +Cc1ccc(S(=O)(=O)N2CCN(C(C)CC#N)CC2)cc1C +Cc1c(C(=O)Nc2ccc(C#N)cc2)cnn1-c1ccccn1 +CCOc1ccc(F)c(C(=O)N2CCC3(CC2)OCCO3)c1F +c1ccc2c(CCNc3ccc4nncn4n3)c[nH]c2c1 +Cc1ccc(C(=O)CCC(=O)Nc2ccccn2)s1 +Cc1nccc(C(=O)N2CCCSc3ccc(Cl)cc32)n1 +Cc1nc(CN2CCN(c3ccc(Cl)cc3)CC2)cs1 +CC(C)(C)n1nnnc1CN1CCN(c2ccc(F)cc2)CC1 +Cc1cccc(C(=O)NC(C(=O)N(C)Cc2ccccc2)C(C)C)c1 +COc1ccc(NCc2ccc(C(N)=O)cc2F)cn1 +COCCNC(NC(=O)c1cccs1)C(Cl)(Cl)Cl +C=CCNC(=O)c1ccc(-c2ccc(C)c(Cl)c2)nc1N +COCCN1C(=O)CC2C1CCN2C(=O)c1ccc(C)nc1 +C=CCN(CC=C)C(=O)c1cc(NC(C)=O)cc(NC(C)=O)c1 +CCCNC(=O)C(C)NC(=O)c1oc2c(Cl)cccc2c1C +Cc1csc(N2CCN(C(=O)c3scnc3C)CC2)n1 +COc1ccc(Cl)cc1C(=O)N1CCCC1C(=O)N(C)C(C)C +COc1ccc(-n2cc(CNC(=O)c3cc(C)c(C)s3)nn2)cc1 +Cc1ccc2ncc(C(=O)N3CCN(CCOC(C)C)CC3)n2c1 +CC(C)C(C#N)N1CCN(C(=O)c2ccc(-n3cccc3)nc2)CC1 +Cc1cccc(C(=O)N2CCCC2)c1NC(=O)c1ccc(=O)n(C)n1 +Cc1ccc(OCC(=O)N2CCN(c3c(C)n[nH]c3C)CC2)cc1 +N#Cc1ccc(OCCCSc2nnc(-c3ccncc3)o2)cc1 +COc1ccc(NC(=O)COc2ccc(F)c(F)c2)c(OC)c1 +CC(C)N1CC(C(=O)NCC2CCCO2)CC1=O +CCC1CCCCN1S(=O)(=O)CCc1ccccc1 +CCC(CO)n1cc(O)c(=O)cc1CN1CCOCC1 +CC(C)Oc1ccc(CNC(=O)C2CCCO2)cc1 +CC(NC(=O)c1n[nH]c2c1CCCC2)c1ccccc1 +COCC(O)CN(C)C(=O)C1CC(=O)N(C2CC2)C1 +Nc1ccc(-c2nnc(-c3cccc(Cl)c3)o2)cc1 +O=C(NCc1cccnc1OC1CCCC1)c1c(O)cc(F)cc1F +COC(=O)CC1Oc2ccccc2N(Cc2nncn2C(C)C)C1=O +CC(=O)c1cccc(NC(=O)C2(c3cc(-c4ccco4)on3)CC2)c1 +CNc1nc(-c2ccc(C(C)C)n(CCOC)c2=O)cs1 +Cc1ccccc1OCc1ccc(C(=O)NC(C)C)o1 +CCc1cc(=O)[nH]c2nnc(SCc3cccnc3)n12 +COc1cc(N)ccc1NC(=O)COc1cccc(F)c1 +CCCCN1C(=O)C(O)(c2c(C)nn(CCO)c2N)c2ccccc21 +COCCOc1ccc(C2Nc3ccccc3C(=O)N2C)cc1OC +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccc(N2CCNC2=O)cc1 +CC(=O)c1ccc(N2CCN(C(=O)CNC(N)=O)CC2)cc1 +Cc1ccsc1CNC(=O)C1CCCCN1S(C)(=O)=O +Cc1cc(C(=O)NCc2csc(=O)[nH]2)c(Cl)cc1F +CCOCCCNc1ccc2nc3ccc(C)cc3c(=O)n2n1 +Cc1cc(C(=O)N2CC(C(=O)Nc3ccc(C)c(C)c3)C2)no1 +CC(=O)N(C)Cc1cccc(NC(=O)N(C)CC2CCCC2)c1 +CC(NC(N)=O)C(=O)NC1(c2ccc(Br)cc2)CC1 +O=C(Nc1nc2ccc(F)cn2n1)c1ccc2ccc(Cl)cc2n1 +CSc1ccc(Cl)cc1NC(=O)NC1c2ccccc2CC1O +N#Cc1ncn(CC(=O)Nc2ccccc2Cc2ccccc2)n1 +CCCNC(=O)C1CCCN(c2ncnc3onc(CC)c23)C1 +O=C(Cn1ncc(=O)c2ccccc21)Oc1ccc2ccc(=O)oc2c1 +CCOc1cccc2cc(C(C)NC(C)C(=O)OC)oc12 +CC(=O)NCc1nc2ccccc2n1CC(=O)NC(C)(C)C +Cn1c(=O)n(CCC(=O)OCc2ccccc2Cl)c2ccccc21 +CC(C)Oc1cccc(NC(=O)CNc2ccccc2C(N)=O)c1 +COc1ccc(C(C)=O)cc1CC(=O)N1CCOc2ccc(F)cc21 +CC(=O)NC1CCCN(Cc2nc3ccc(Cl)cc3c(=O)[nH]2)C1 +CC1(C)COC2(OC1)C1=NS(=O)(=O)CC13CCC2C3(C)C +CC(c1ccc(F)c(F)c1)N(C)C(=O)Cn1ncn(C)c1=O +Cc1noc(C)c1CC(=O)Nc1ccc(-c2nc3ccccc3o2)cc1 +Cc1ccc(CC(=O)Nc2cc(N)ccc2Cl)cc1 +CCc1nnc(C(C)Sc2nnc(C)n2-c2cccc(C)c2)o1 +COc1ccc2c(c1)CN(C(=O)NCCc1cccnc1)CC2 +COC(=O)C1CC(Oc2ccc(C)cc2OC)CN1 +COc1cccc(OC)c1CNc1cccc(F)n1 +CCOc1cc(C)nc(N2CCN(CC(O)C(F)(F)F)CC2)n1 +Cc1ccc(-c2cc(Nc3ccc(C(N)=O)cc3)nc(C)n2)cc1 +O=C(CCC(=O)N1CCOCC1)Oc1ccc(Br)cc1 +CC1Oc2ccccc2OC1C(=O)NCc1nnc2n1CCC2 +O=C(NCc1ccccc1-n1cccn1)c1ccco1 +CC(CO)(CO)NC(=O)c1ccc(-c2ccc(F)cc2)cc1F +O=C(Nc1ccc2ccccc2c1)C1CCCN(C(=O)C2CC2)C1 +CCOc1ccccc1CNC(=O)c1cc(C(N)=O)cs1 +Cc1noc(C)c1S(=O)(=O)N1CCn2cccc2C1C +CC1CCCN(c2ncnc(NCCN3CCOCC3)c2N)C1 +COc1ccc(SC(C)C(=O)NCc2ccccc2OC)cc1 +CCn1c(=O)c2c(nc(SCc3ccc(F)cc3)n2C)n(C)c1=O +CN(c1cccc2ncccc12)S(=O)(=O)Cc1ccccc1 +CC(C)c1ccc(-c2ccc(CO)c(=O)n2C)cc1 +COc1cccc(OCCNC(=O)NCc2cscn2)c1 +CN(C)C(=O)N1CCN(C(=O)NC2CC3CCC2(C)C3(C)C)CC1 +Cc1ccc(-c2nnc(C(C)N3CCc4cncnc4C3)o2)cc1 +CCc1nn(CCCN2CCOCC2)c2c1C(=O)CCC2 +CCOCCNC(=O)N(CC)Cc1cccc(C)c1 +NC(=O)c1ccn(-c2ccccc2NC(=O)COC2CCCCC2)n1 +O=C1CN(C(=O)CSc2ncn[nH]2)c2ccccc2N1 +COc1ccccc1S(=O)(=O)NCC(OC)c1ccsc1 +CC(Cc1ccc(Br)cc1)NC(=O)C1CCOCC1 +COCCNC(=O)N1CCN(c2ccccc2F)CC1 +CCCn1nccc1NC(=O)c1ccnc(OC2CCC2)c1 +N#Cc1cccc(NCc2ccc3c(c2)OCO3)c1 +CCc1nc(CSc2nnc(-c3cccnc3)n2C2CC2)cs1 +CCc1nnc(SCC(=O)OC2CCCCC2)n1N +Cc1cccc(OCc2nnc(SCC(=O)c3cnn(C)c3)o2)c1 +CCC(C)NC(=O)c1sccc1S(=O)(=O)N1CCCCC1 +CC(C)(C)OC(=O)NCC(=O)N1CCCC1CC(=O)c1ccccc1 +CC(C)(CCC(=O)OC(C)(C)C)NC(=O)c1ccc(F)nc1 +N#Cc1cccc(NCC(=O)Nc2ccc(F)cc2)c1 +CCCCCC(=O)Nc1ccc(S(N)(=O)=O)cc1F +Cc1cc(NC(=O)C2CCN(S(C)(=O)=O)CC2)no1 +CC1(C)CN(C(=O)NCCc2cnn(-c3ccccc3)c2)CCO1 +NC(=O)C1Cc2ccccc2N1C(=O)Cc1c[nH]c2ccccc12 +Cc1nnc(CN(C)C(C)c2cccc(Cl)c2)n1C +CCn1c(SCc2nnc(C)o2)nnc1-c1cccc(Cl)c1 +Cc1cccc(C)c1CCNC(=O)c1cnc(C2CCCO2)s1 +O=C(Nc1cccc(F)c1)c1cc2c(cc1Cl)OCCO2 +Cc1ncnc(C)c1C1NCCc2ccc(F)cc21 +CC(=O)Nc1ccc(CC(=O)NCc2cccs2)cc1 +CCC(=O)N1CCC2(CC1)Nc1ccccc1-n1cccc12 +CCC(=O)NC(C)c1nc2ccccc2n1CC(=O)NC1CCCC1 +Cc1cc2cc(NC(=O)CCc3ccco3)ccc2[nH]1 +O=C(NCc1ccc2c(c1)OCO2)Nc1ccncc1 +COCCCC(=O)Nc1ncc(Cc2ccc(C#N)cc2)s1 +CN(CC1CCCC1)C(=O)c1cc(S(C)(=O)=O)ccc1Cl +Nc1ccc(S(=O)(=O)Nc2ccccc2C(F)(F)F)cc1 +CCc1nnc(COC(=O)c2cccc(-c3ccoc3)c2)n1C +CCOC(=O)CSc1nnc(-c2ccc(O)cc2)n1C +CCCCN(C)C(=O)Cc1csc(NC(=O)c2cccc(O)c2)n1 +CCCNC(=O)c1cccc(NC(=O)c2cnc3ccc(C)cn23)c1 +Cc1ccc(-n2nc(C)cc2NC(=O)c2ccc(C)s2)cc1 +Cc1cc(Br)cn2c1nc1c(=O)[nH]cnc12 +CC(=O)Nc1ccc(C)c(S(=O)(=O)NCCC2CCCCC2)c1 +COc1ccccc1CC1Oc2ccc(N)cc2NC1=O +CC1CCc2c(sc3nc(CSc4ncn[nH]4)nc(N)c23)C1 +Cc1ccccc1N1CC(C(=O)NC2CCCC2)CC1=O +CC(=O)Nc1ccc(OC(=O)c2ccc(C)[nH]c2=O)cc1 +COc1ccc(-c2nc(COC(C)=O)cs2)cc1 +CC(Oc1ccccc1C#N)C(=O)N1CCc2ccccc21 +Cc1ccc(C(=O)NC(C)C(=O)N2CCCCC2)s1 +C=CCN(Cc1ccccc1)C(=O)c1cncc2ccccc12 +N#CCC(c1ccccc1)N1CCCCC1C(N)=O +COc1ccc(N)cc1CNC(=O)c1cccnc1 +CC(C)Nc1nc(-c2cnc(-c3ccccn3)s2)cs1 +Cc1ccc(OCCNC(=O)c2n[nH]c(=O)[nH]2)cc1 +O=C(NCc1ccc(F)cc1)c1noc(-c2cnccn2)n1 +COc1ccc(OCC(=O)c2ccc(NC(C)=O)cc2)cc1 +COc1ccc2c(ccn2CC(=O)NCc2csc(=O)[nH]2)c1 +O=c1c(N2CCCCC2)nsnc1N1CCCCC1 +Cc1ccc(N2CC(C(=O)Oc3ccc4c(c3)ncn4C)CC2=O)cc1 +NS(=O)(=O)CCNC(=O)CCCc1nc2ccccc2s1 +CCCC(C)N(C)S(=O)(=O)c1ccc(NC)cc1 +COCC(=O)N(C)c1nnc(-c2ccccc2OC)s1 +CCc1cc(C(=O)NCC2CCOc3ccccc3C2)cc(=O)[nH]1 +Cc1nc(C)c(CC(=O)N2CCOCC2C2CC2)c(=O)[nH]1 +N#Cc1ccccc1NC(=O)COC(=O)Cc1ccccc1F +O=C(NCCc1c(F)cccc1F)Nc1nncs1 +Cc1cc(NC(=O)NC2CCC(O)CC2)n(C)n1 +COc1ncnc2c1CN(Cc1ncc(C(C)(C)C)o1)CC2 +CC(NC(=O)c1c(O)cc(F)cc1F)c1ccco1 +Cn1nc(CNC(=O)c2ccc(F)c(F)c2)cc1-c1cccs1 +CCc1cc(CNC(=O)c2coc(COc3cccc(F)c3)n2)on1 +COc1ccc(CNC(=O)C(C)Oc2ccc(C)cc2)cc1 +CCCCS(=O)(=O)c1ccc(C(=O)CC)cc1 +COC(=O)c1nc(C2CC2)ncc1Br +O=C(c1ccc(-n2cnnn2)cc1)N1CCCC1CCc1ccccc1 +Cn1ccc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)n1 +COc1ccc(CNC(=O)Nc2cccc(F)c2)cc1 +Cc1nc(NC(=O)NCC2CCN(C(=O)C3CC3)CC2)nn1C(C)C +NC(=O)C1CCN(C(=O)Nc2nnc(-c3ccccn3)s2)C1 +COc1ccc(CCC(=O)NCC2CC2)cc1OC +CC(C)(C)c1c(CO)nnn1CC(=O)Nc1ccccn1 +CCOC(=O)CC(O)(c1cc2ccccc2[nH]1)C(F)(F)F +COc1ccccc1C(=O)NC(C#N)c1cccnc1 +Cc1ccn2c(=O)c(C(=O)NC(C)CN3CCOCC3)cnc2c1 +CC(=O)Nc1cccc(NC(=O)c2cccs2)c1C +NC(=O)c1ccc(C(=O)Nc2ccccc2F)cn1 +Brc1c[nH]c2snc(-c3ncco3)c12 +CN(C)C(=O)c1ccc(NC(=O)COc2ccccc2CO)cc1 +Nc1nc(-c2ccccc2)ccc1C(=O)Nc1ncccn1 +COc1cccc(-n2ccnc2SCC(=O)c2ccc[nH]2)c1 +O=S(=O)(Oc1cccc(-n2cnnn2)c1)c1cc(F)cc(F)c1 +COc1ccccc1NCC(=O)NC(C)c1ccccc1 +CCn1cc(CN(C)S(=O)(=O)c2c(C)nn(CC)c2C)c(C)n1 +Cc1c(C)n2c3c(=O)n(CCC(C)C)c(=O)n(C)c3nc2n1C +COc1ccc(NC(=O)c2ccc(F)cc2F)cc1 +C=CCOc1ccc(CN(C)Cc2nc(C)cs2)cc1Cl +Cc1ncc(N)cc1C(=O)N(C)CC(=O)NC1CC1 +NC(CCc1ccccc1)C(=O)NCC(O)CO +COc1ccc(F)c(NC(=O)c2cc(C)c(C)s2)c1 +CC1CN(C(=O)CSc2ccncc2N)CCO1 +Cc1cc(C)n(-c2cc(NC3CCCCCC3)ncn2)n1 +NC(=O)c1cc(NC(=O)N2CCOCC2C2CC2)ccc1F +Nn1c(C(=O)NCC2CCCO2)nc2ccccc2c1=O +COc1ccc(NC(=O)CC(c2ccco2)C(C)C)cc1 +C=C(C)COCCNC(=O)NC1CCN(c2ncccc2F)C1 +CC(=O)NC(C(=O)Nc1ccccc1SCC(C)C#N)C(C)C +Cc1c(-c2ccc(Cl)cc2)nc2c(N)cccn12 +CC(=O)N1CCCC1c1nc(C)cc(-c2ccc(N)nc2)n1 +Cc1cccc(-c2c(CO)nnn2Cc2ccc(F)cc2)c1 +C=CCOCC1CCC2C1OCCN2C(=O)C1CCCO1 +CCNC(=O)CN1CCN(C(=O)NCCc2cccc(C)c2)CC1 +CCn1c2c(ccc1=O)CC(NC(=O)c1ccnnc1)CC2 +CN1C(=O)c2oc3ccccc3c(=O)c2C1c1cccc(F)c1 +CC1CN(C(=O)NCCc2ccc3c(c2)CCO3)CC(C)O1 +NC(=O)N1CCCC(C(=O)OCCc2ccccc2F)C1 +CCOc1cccn2c(-c3ccc(N)cc3)nnc12 +Cc1cnc(C(=O)Nc2cccc(C(N)=O)c2)cn1 +O=C(Cc1ccccc1)Nc1ccccc1C(=O)NCc1ccccc1 +CNC(=O)c1nn(C)cc1NC(=O)c1ccc(C)cc1C +Fc1cccc2c1OCCC2NCCCN1CCOCC1 +CCc1nc2scc(-c3ccc(C)cc3)c2c(=O)n1N +O=C(Cc1ccc(F)cc1F)NCc1cccnc1 +CC(NC(=O)CCCNC(=O)c1ccc(Cl)cc1)C1CCCO1 +COC(=O)NCC(=O)Nc1ccc2nc[nH]c(=O)c2c1 +CC(NC(=O)Nn1cnc2ccccc21)c1cccc(-n2cccn2)c1 +N#CC1(C(=O)NCCNc2nnnn2-c2ccccc2)CCCCC1 +CCn1nnc(NC(=O)COc2ccc(C(C)(C)C)cc2)n1 +CCN(CC)C(=O)c1c(C)nn(-c2cccc(C)c2)c1-n1cccc1 +CNc1nccc(N2CCC(CC(=O)NCCOC)CC2)n1 +Cc1ccc(S(=O)(=O)CCC(=O)N(C)Cc2ccccc2)cc1 +CC(C)CC(C)N(C)C(=O)Cn1nc(-c2ccco2)oc1=O +CC1(c2ccccc2)OC(O)CC1n1nc2ccccc2n1 +Cc1ccc(C(=O)Nc2cc(F)c(F)c(F)c2)s1 +CC(C)Cn1c(=O)c(C(=O)NCc2ccncc2)nc2cccnc21 +COc1cc(OC)cc(C(=O)N2CCOC(c3ccccc3)C2)c1 +FC(F)(F)CSc1nc2ncccc2s1 +CCCn1nc(C(=O)Nc2nc(-c3ccccc3)cs2)ccc1=O +Cc1nc2cc(C3CCOCC3)nn2c(N2CCC(O)C(C)C2)c1C +COCCN(CCC#N)C(=O)c1ccc(Cl)c(N)c1 +COC(=O)c1ncn(CC(=O)Nc2ccccc2-c2ccccc2)n1 +COCCn1c(SCC(=O)NC2CCCCC2)nc(C)c1C +C#Cc1cccc(NC(=O)COc2ccc(Cl)cc2)c1 +CC(=O)NCc1ccc(C(=O)Nc2c(C)cc(C)cc2Cl)cc1 +CCC(=O)Nc1ccc(NC(C)C(=O)Nc2cc(C)no2)cc1 +CCc1ccc(NC(=O)C(C)OCC2CC2)cc1S(N)(=O)=O +Cc1ccc(N)cc1S(=O)(=O)NCCC1CCCC1 +O=C(c1cccs1)N1CCC1c1nc(-c2cccnc2)no1 +CC(=O)N1CCC(c2cncc(-c3cccc(Cl)c3)n2)CC1 +CC1CCC(NC(=O)C2CC3CCCC(C2)C3=O)CC1 +Cc1cc(F)c(C(=O)OCCCn2cccn2)cc1F +COCCC(=O)Nc1ccc2c(c1)OC(F)(F)O2 +Cc1ccn2c(=NC(=O)c3csc(-c4ccoc4)n3)[nH]nc2c1 +CN1CCN(C(=O)COc2ccccc2C#N)C(c2ccccc2)C1 +Cc1cccc(OCC(=O)N2CCc3ccc(N)cc3C2)c1 +OCC1(CSc2cc3c(cc2Cl)OCCO3)COC1 +O=C(NCC1(c2ccccc2)CCC1)c1cnc2ccccn2c1=O +Cc1csc(=O)n1CCC(=O)OCC(=O)Nc1ccccc1 +CC(Nc1ccc(C#N)cn1)c1ccccc1C(F)(F)F +Cc1n[nH]c(C)c1N1CCN(C(=O)Cc2noc3ccccc23)CC1 +O=c1c(-c2nc(-c3ccc4c(c3)OCO4)no2)c[nH]c2ccccc12 +COc1ccc(C2=CC(c3ccco3)n3nc(C)nc3N2)cc1OC +O=S(=O)(c1ccc(SCCc2ccccc2)nc1)N1CCCC1 +CC(NC(=O)Cc1csc(-n2cccc2)n1)c1ccccc1 +CC(C)c1ocnc1C(=O)NCCCn1cnc2ccccc21 +CCCC(=O)Nc1cc(-c2nn3cnnc3s2)ccc1OC +CC(C)N(C)c1cccc(NC(=O)CCSc2ccccn2)c1 +c1ccc(CCN(Cc2cccnc2)c2ncccn2)cc1 +CCOC(=O)Cn1ncn(-c2ccc(C)cc2)c1=O +CCCCNC(=O)C(C)N(c1cc(C)cc(C)c1)S(C)(=O)=O +CCC1CCCCC1NC(=O)C1CC(=O)N(CCOC)C1 +Cc1ccc(-n2c(C)cn3c4c(=O)[nH]c(=O)n(C)c4nc23)cc1 +O=C(CSc1nnnn1CCCO)Nc1ccc2c(c1)OCO2 +CC(c1ccccc1Cl)N(C)C(=O)c1cccc2cn[nH]c12 +Cc1cc(NC(=O)CCNC(=O)c2ccco2)no1 +CC(C)c1csc2nc(Cc3cccc(C(N)=O)c3)[nH]c(=O)c12 +O=C(NCCC(=O)N1CCOC(c2ccccc2)C1)c1ccccc1 +CC(=O)Nc1ccc(NC(=O)CCc2ccccc2F)cc1 +COC(=O)c1sc2cc(=O)n(-c3ccc(Cl)cc3)nc2c1N +CSc1nnc(COc2ccc(C#N)cc2Cl)s1 +COc1cc(N)ccc1-c1nn2c(C(C)C)nnc2s1 +Cc1n[nH]c(SCC(=O)c2ccc3c(c2)-c2ccccc2C3)n1 +CCC(CC)N(C)C(=O)Cc1coc2cc(OC)ccc12 +CCOc1ccc2nc(C(=O)NC(C)c3ccccn3)cn2n1 +CC(NCCN1CCOCC1)c1ccc(F)c(Cl)c1 +Cc1c(Sc2nnnn2C)nn2c(C(F)(F)F)nnc2c1C +CC(C)N1CCOC2CN(C(=O)c3ccncc3F)CC21 +CCC(Cn1nc(-c2cccs2)ccc1=O)NC(=O)C(C)C +CCCC(=O)N1CCN(c2ccc(Cl)cc2N)CC1 +CC(Sc1nnnn1-c1cccc(F)c1)C(=O)N1CCCC1 +CC(C)c1cc(Nc2cnn(CCO)c2)nc(C(C)C)n1 +Cc1nc2nc(SCc3ccc4ccccc4n3)nn2c(C)c1C +COCCN1CC(C(=O)NCc2cccc(C)c2)CC1=O +O=C(c1csnn1)N1CCOC2C(CNc3cccnc3)CCC21 +CN(CC1CCOCC1)c1cc(N(C)CC2CCOCC2)ncn1 +CCS(=O)(=O)N1CCN(c2c(C)nn(-c3ccccc3)c2C)CC1 +N#Cc1c(N)nc2c(c1-c1cnc(-c3ccccc3)nc1)CNCC2 +CCOC(=O)C(C)Sc1nc2ccccc2[nH]1 +NC(=O)CCSc1nnc(-c2ccncc2)o1 +CC(C)CNC(=O)c1nn(C)c2ccccc2c1=O +CCOC(=O)N1CCN(c2cccn3nc(N)nc23)CC1 +CC(C)n1c(CCNC(=O)c2ccccc2)nc2cccnc21 +CCN(CC)S(=O)(=O)c1cc(C(=O)Nc2cccnc2)ccc1C +O=C(C1COc2ccc(F)cc2C1)N1CCOc2ncccc21 +COc1cc(OC)cc(C(O)c2sccc2C)c1 +CC(C)(CNC(=O)Cn1nnc2ccccc2c1=O)c1ccncc1 +O=S(Cc1nnnn1-c1ccccc1)c1cccc(F)c1 +Cn1cc(C(=O)N(Cc2cc(F)ccc2F)C2CCCC2)cn1 +CC(Nc1cccc(C(N)=O)c1)C(=O)Nc1ccc2c(c1)OCO2 +CCOc1ccc(NC(=O)N2CCC(OCC(C)C)CC2)c(C)c1 +O=C(Nc1ccc(F)cc1)NC1CC2C(=O)NC(CO)C(=O)N2C1 +Cc1ccc(N2CCCC2=O)c(C(=O)NCCc2ccc(F)cc2)c1 +C=CCc1ccc(OC(=O)c2cnn(-c3ccncc3)c2C)c(OC)c1 +O=C(C1CCC(c2ccccc2)CC1)N1CCc2[nH]ncc2C1 +COC(=O)c1ccccc1C(=O)NCC#Cc1ccc(C(N)=O)cc1 +Cc1cnc(NC(=O)Cn2c(C)cc3ccccc32)s1 +COc1cccc(CNC(=O)C(C)N2Cc3ccccc3C2=O)c1 +CCN1CCN(C(=O)COc2ccc(-n3cnnn3)cc2)CC1 +CN(Cc1ccc(OC(F)F)cc1)CC(O)c1ccccc1F +COc1cc(C(=O)NCc2ccco2)cc(Cl)c1OCC(C)C +CC(C)CNc1nc(-c2cccn(CC(C)C)c2=O)cs1 +CCOc1ccc(NC(=O)c2ccno2)cc1CO +CC(=O)c1ccc2c(c1)N(C(=O)C(C)C)CC(C)(C)O2 +CCCC(=O)N1CCCC1C(=O)N1CCOC(C)(C)C1 +CCc1nc(NC(=O)c2cc3occc3[nH]2)sc1C(=O)OC +CC(=O)Nc1ccc(C)n(CC(=O)NCc2ccc(C)cc2)c1=O +Cn1cc(C(=O)NCc2ccccc2)c(=O)c2cccc(F)c21 +CC(=O)Nc1cccc(NCC(=O)Nc2ccccc2OC(F)F)c1 +c1ccc2oc(CN3CCN(c4cnccn4)CC3)nc2c1 +Cc1ccc2c(C)c(C(=O)NCCCn3nc(C)nc3C)oc2c1 +COCCN(C)C(=O)NCCCn1ccc2ccccc21 +Cc1ccc(C(O)CNC(=O)c2cccc3ccccc23)o1 +O=S(=O)(Cc1nc(C2CC2)no1)c1nc2ccccc2[nH]1 +Cc1cc(N)c2oc(C(=O)NCCCCCO)cc(=O)c2c1 +CC(C)Cc1ccc(C(NCC(=O)N(C)C)C(C)C)cc1 +CCn1nc(-c2cccc(OC)c2)cc1C(=O)NCc1ccncc1 +Cc1n[nH]cc1NC(=O)c1cc2ccccc2s1 +COc1ccc(NC(=O)N(C)C(C)c2cccc(O)c2)cc1OC +Cc1ccc(C)c(S(=O)(=O)Cc2cccc(C(N)=O)c2)c1 +COc1ncccc1C(=O)NCCC12CC3CC(CC(C3)C1)C2 +CCCC(=O)NCC(=O)NCc1cccnc1OC +CC(C)NC(=O)Cc1ccc(NC(=O)Cc2ccc[nH]2)cc1 +CC(=O)Nc1ccc2ncn(-c3ccncc3)c2c1 +Cc1noc(C)c1CN(C)C(=O)NCC1CN2CCCC2CO1 +Cc1nc(C(F)(F)F)ccc1C(=O)NCC1(CCO)CCCCC1 +CC1CCCN(C(=O)CSc2nccn2C)C1 +COCc1ccccc1C(=O)Nc1cc(OC)c(Cl)cc1OC +NS(=O)(=O)c1ccc(C(=O)Nc2cccc(Cl)c2)o1 +COC(=O)CNC(=O)c1c(Cl)cccc1Cl +CNc1snc(C)c1C(=O)NCCc1ccc(Cl)cc1 +CC1CN(C(=O)Nc2cccnc2)CC(c2ccccc2)O1 +COc1ccc(OC)c(-c2ncnc3scc(C)c23)c1 +Cc1ccc(-n2nnc(CO)c2Cc2ccccc2)cc1 +CCC1CN(C)c2ccccc2CN1C(=O)CCOC +Cc1cccc(OCC(=O)NCC(O)c2cccn2C)c1 +COc1cc(C(=O)N(C)Cc2cc(C)on2)cc(Cl)c1OC +CC(=O)NCC(=O)N(Cc1ccc(Cl)cc1)C1CC1 +CNC(=O)COc1ccc(Cl)cc1Br +Cc1cc(C(=O)N2CCN(c3nc4ccccc4s3)CC2)on1 +CN(C(=O)NC(Cn1cncn1)c1ccccc1)C1CCC1 +CCOC(=O)c1ccc(N(C)S(=O)(=O)c2ccccc2)cc1 +CCN(C(=O)Cc1ccc(C)nc1)c1ccc(F)cc1 +CCCC(C)(NC(=O)c1cnc(C2CCCO2)s1)C(=O)OC +N#Cc1cccc(C(=O)N2CCC(c3cccs3)CC2)c1 +CN(Cc1ccc2c(c1)OCCO2)c1ncccc1C#N +CCCNC(=O)c1cccc(C(=O)N2CCCCC2C(=O)OC)c1 +COc1ccc(CCNS(=O)(=O)c2cccc(O)c2)cc1 +Cc1ccc2ncc(C(=O)OCC3CC3(Cl)Cl)c(=O)n2c1 +COc1ccccc1S(=O)(=O)Oc1cccc2cccnc12 +O=C(OCCCc1cccnc1)c1ccc(C(F)(F)F)nc1 +CC(C)COc1ccc(CCC(O)c2ccccn2)cc1 +COCc1cc(=O)[nH]c(Nc2ccc(F)c(F)c2)n1 +Cn1cnnc1SCc1nc2cc(Cl)ccc2n1C +Cc1ccc2c(c1)SCC(=O)N2Cc1noc(C(=O)N(C)C)n1 +CN(C)S(=O)(=O)N1CCN(c2ccc(N3CCCC3)nn2)CC1 +O=C(NCCc1cccc(F)c1)NCc1cscn1 +CS(=O)(=O)N(CCCO)c1cc(Cl)cc(Cl)c1 +O=C(OCC(=O)N1CCOCC1)c1n[nH]c2ccccc12 +Cn1ncc2c(=O)[nH]c(N3CC4CC5CC(C4)CC3C5)nc21 +Cc1cc(Cl)ccc1OCc1nc(N)nc(C)c1C(N)=O +CCCNc1nnc(-c2cc(C)nn(CC)c2=O)s1 +CS(=O)(=O)N1CCCC(C(=O)OCCCc2ccccc2)C1 +Cc1nn(CC(=O)NCC2CCCC(C)C2)c(C)c1Cl +CC(C1CC1)N(C(=O)CN(C)c1ccc(F)c(F)c1)C1CC1 +Cn1nccc1CNC(=O)N1CCOCC1C1CC1 +CN(CC1CCCC1)C(=O)CCCCNC(N)=O +COc1ccc(Cl)cc1C(=O)NCC(=O)NC(C)(C)C +COC(=O)c1csc(NC(=O)Cc2c[nH]c3ccccc23)c1 +Cc1noc(NC(=O)CCc2c[nH]c3ccccc23)n1 +COC(=O)c1cccc(NC(=O)CCC(=O)c2cccs2)c1 +NC(=O)COc1ccc(NC(=O)NCc2ccccn2)cc1 +CC(=O)Nc1ccc(F)c(C(=O)N2CCCCCC2)c1 +CC(C)c1noc(OCC(=O)NC(C)(C#N)C(C)C)n1 +c1ccc(OCC23CCCC2CN(c2ncccn2)C3)nc1 +COc1cc(C(=O)Nc2cccc(C)c2)cc(OC)c1OC +O=C(Cn1cccn1)NCC1(c2ccc3c(c2)OCCO3)CCCC1 +O=C1CCc2cc(F)c(NC(=O)c3ccoc3)cc2N1 +Cc1ccccc1CNC(=O)c1ccc(Cn2cncn2)cc1 +O=C(Cn1cnc2sccc2c1=O)NCCSc1ccccc1 +CC(C)NC(=O)NCC#Cc1cccc(Cl)c1 +CCOC(=O)c1cc(C(=O)Nc2ccc(F)cc2)c(=O)[nH]c1C +N#Cc1ccc(OC2CCC(NC(=O)C3CCOCC3)CC2)nc1 +Cc1c[nH]c(=NC(=O)c2ccc(-n3cnnc3)cc2)[nH]1 +CN(C)C(=O)c1ccccc1NC(=O)CCSc1ccccn1 +Cc1ncsc1CN1CCN(CC(F)F)CC1 +N#CCCC(C#N)Cn1nnc(-c2ccc(Cl)cc2)n1 +CCc1nc(C(=O)NC2CCC(C)CC2)nn1-c1ccccc1Cl +COc1ccc(Cl)cc1-n1ccc2c(cnc3ncnn32)c1=O +CCC(=O)c1cccc(NC(=O)N2CCC(c3nncn3C)CC2)c1 +Cc1ccc(C)c(OC(C)C(=O)NCCNS(C)(=O)=O)c1 +COCC(NC(=O)c1cc(C)nc2c1c(C)nn2C)C(N)=O +Cn1cc(Cl)cc1C(=O)N1CCc2ccccc2C1 +CCC(C)(O)CNC(=O)Nc1cccc(-c2nnnn2C)c1 +Cc1cccc(NC(=O)c2nccc3ccc(N)cc23)n1 +COC(=O)CCC(=O)N(C)Cc1ccc(F)cc1 +Cc1c(Cl)cccc1NC(=O)Cn1cnc2onc(C)c2c1=O +CC1CCCCN1C(=O)c1cccc(NS(C)(=O)=O)c1 +Cc1ccc(NC(=O)CN2C(=O)CN(C)C(=O)c3ccccc32)cc1 +COC(=O)c1ccc(N2CCN(C(=O)Cn3cnnn3)C(C)C2)cc1 +C=CCN(Cc1ccc(OC)cc1)C(=O)c1ccc(C)cc1 +O=C(Nc1nc[nH]n1)c1ccc(-c2ccc(F)cc2)cc1F +Cc1ccc(Cl)cc1NC(=O)C(O)c1ccccc1 +Cc1noc(C)c1CC(=O)OC(C)C(=O)c1c(C)[nH]c2ccccc12 +Cc1cc(CC2COCC2NC(=O)Cc2c[nH]c(=O)n(C)c2=O)on1 +CCC(C)C(C)NC(=O)c1cccc(NC(N)=O)c1 +c1ccc(OCCCn2nnc3ccccc32)cc1 +CCOc1ccc(C(=O)N(CC)CC(=O)NC(C)C)cc1 +O=C(Cc1cccc2cccnc12)Nc1cc(C(F)(F)F)c[nH]c1=O +COc1ccc(NC(=O)CSc2nn3cnnc3o2)c(OC)c1 +c1ccc(C2=Nn3cnnc3SC2c2ccccc2)cc1 +CS(=O)c1ccc(C(=O)Nc2ccc(OCC(N)=O)cc2)cc1 +Fc1ccc(CSc2ncnc3nc[nH]c23)c(Cl)c1 +O=C(NCC1CC=CCC1)Nc1cccc(Cn2cncn2)c1 +CN(C)c1nnc(S(=O)(=O)CC(=O)NCc2cccs2)s1 +CCC(O)c1ccc2c(c1)C(NC(=O)C1CC1)CCC2 +CN1CC2CCC(CC1=O)N2C(=O)c1ccc2c(c1)N(C)C(=O)CO2 +Cc1ccccc1CC(=O)NC(CO)C(O)c1ccc(N)cc1 +O=C(Cc1noc(C=Cc2ccccc2)n1)NC1CCCC1 +Cc1noc(C)c1C(C)Cc1nc(-c2ccc3c(c2)CCO3)no1 +CC(=O)N1CC2(CCN(C(=O)N(C)C)CC2)c2cc(C)ccc21 +Cc1ccc2cccc(C(=O)Nc3ccc(C#N)c(Cl)c3)c2n1 +CCc1nc(CN2CCN(Cc3ccnn3C)CC2)cs1 +Cc1cc(C)c(C(=O)Nc2ccc(N(C)C(C)C)c(F)c2)c(=O)[nH]1 +Fc1cccc2c1CN(Cc1cnc(-c3cccnc3)s1)CC2 +CCN(Cc1ccncc1)C(=O)c1ccc(F)cc1F +C=C(C)COc1cccc(C(=O)Nc2ccccc2NC(C)=O)c1 +COc1ccc(NC(C)=O)cc1NC(=O)CCc1cccs1 +CCCOc1ccc(C(=O)NCC2CCCO2)cc1 +CC(=O)N1CCCC1C(=O)NC(C)c1ccccc1C(F)(F)F +O=C(Nc1cccc(C#CCCO)c1)c1ccno1 +Cc1n[nH]c(C)c1C(C)N(C)C(=O)c1ccc2cccc(F)c2n1 +Nc1ccc2nc(NC(=O)c3cccc(Cl)c3)sc2c1 +Cc1ccccc1CC(C#N)C(=O)N1CCCCCC1 +Cn1c(N)nnc1SCC(=O)NC(C1CC1)C1CC1 +CC(=O)Nc1ccc(C(O)CN2CC(C)OC(C)C2)cc1 +O=C(Nc1ccc(Cl)cc1)Nc1nc(O)cs1 +Cc1nc(C)c(C#N)c(SC(C(=O)NC(C)(C)C)C(C)C)n1 +O=C(C1CC12CCOCC2)N1CCC(Oc2cccc(Cl)c2)C1 +CC1CN(CCNC(=O)N2CCN(c3ncccn3)CC2)CC(C)O1 +COCCN1CCN(C(=O)NCCCc2cnn(C)c2)CC1=O +Cc1csc(NC(=O)C2COc3ccc(Cl)cc3C2)n1 +O=C(NC(c1ccccc1)c1ccccc1)c1cc[nH]n1 +O=C(CC1C=CCC1)Nc1cccc(C(=O)NC2CC2)c1 +COc1ccccc1CN1CCC(c2nnc(-c3cncn3C)o2)C1 +O=C(NCC(=O)N1CCCC1c1ccccn1)c1ccccc1Cl +COc1cccc(C(=O)OCC(=O)N2CC(C)CC(C)C2)c1OC +CC(O)c1nc2cc(F)ccc2n1Cc1cccnc1 +O=c1cc(C2CCC2)ncn1Cc1nc(Cc2ccccc2)no1 +O=C(NC1CCCCCC1)C1CCCN1C(=O)C1CC1 +O=C(COCC1CC1)Nc1cnc(-c2cccc(O)c2)nc1 +O=C(NCCCOCC1CCOC1)NC1CCCCc2ccccc21 +CC(=O)NCCNC(=O)NC(C)Cc1ccc(Br)cc1 +CC1(C)CC(=O)c2c(SCCO)sc(C#N)c2C1 +CSc1ccc(C(=O)Nc2nnc(-c3ccccc3)o2)cc1 +CN(CC(F)(F)F)C(=O)CNc1c(Cl)cccc1C#N +COc1ccccc1CCNC(=O)c1c(Cl)cnn1C +CCCc1noc(CS(=O)(=O)c2ccccc2OC)n1 +CCOc1ccc(C(=O)Nc2cc(-c3ccccn3)no2)cc1 +CCCNC(=O)C1CCN(C(=O)c2cc(-c3cccnc3)[nH]n2)CC1 +Cc1sc2nc(-c3cccnc3)nc(N3CCNC(=O)C3)c2c1C +O=C(c1cnn(-c2ccc(Cl)cc2)c1)n1ccnc1 +Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)c1ccc(C#N)cc1 +O=C(COC(=O)C1Cc2ccccc2S1)C1=NC=CC1 +COC(=O)c1cc(C)ccc1OCc1cc(C)on1 +CC(Sc1nnc(N)n1C(C)C)C(=O)NC(C)(C)C +COc1ccccc1NC(=O)NCc1ccc(F)cc1 +CC(C)Cc1ncc2c(n1)CN(c1cc(NCCO)nc(N)n1)C2 +CCCOc1cccc(C(=O)Nc2ccc(OC)c(OC)c2)c1 +O=C(CCNC(=O)C1CCC(O)CC1)Nc1cccc2ccccc12 +Cc1nc2ccccc2n1CC(=O)N1CCOC(C)(C(N)=O)C1 +CCc1ccc(C2C(C(C)=O)C(C(=O)OC)=Nc3nnnn32)cc1 +Cc1ccc(C(=O)Nn2cnc3ccccc3c2=O)cc1C +COc1cc(C)sc1C(=O)NCc1cnn(Cc2ccccc2)c1 +COCc1ccccc1NC(=O)N1CCCC(CO)C1 +N#Cc1ccccc1NS(=O)(=O)Cc1ccccc1Cl +Cc1nn(-c2cccc(Cl)c2)nc1C(=O)NCCCO +CCOc1cc(CNC(=O)Cc2cccs2)ccc1OC +CCC(CC)C(=O)N1CCN(Cc2nc3c(cnn3C)c(=O)[nH]2)CC1 +COC(=O)c1ccccc1NCc1nnc(-c2ccccc2)o1 +CCn1cnnc1-c1cccc(NC(=O)Cn2ccccc2=O)c1 +CC1CCCC(NC(=O)Cc2c(F)cccc2F)C1 +Cn1c(C(=O)N2CCCC2)nc2c1CCN(S(C)(=O)=O)C2 +COC(CNC(=O)Cc1c(C)noc1C)c1ccccc1C +Cc1ccc(=O)n(CC(=O)Nc2ccc3c(c2)COC3)n1 +NC(=O)c1ccc(C(=O)Nc2ccccc2N2CCCCC2)nc1 +COCCOC(=O)CN1CC(C)Nc2cc(C)c(C)cc21 +COc1ccccc1CC1Oc2ccc(N)cc2N(C)C1=O +CC1CCN(C(=O)NCCOCC(F)(F)F)CC1 +Cc1ccnc(NC(=O)C2CCN(C(=O)N(C)C)CC2)c1 +CC(CNC(=O)c1cnc(C2CCCO2)s1)CN1CCOCC1 +COc1cc(CNc2cnn(C)c2C)cc(OC)c1OC +CCNC(=O)N1CC2Cc3c(c(-c4ccccc4)nn3C)C2C1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(F)c(F)c1 +CN(CCCOc1ccccc1)S(=O)(=O)c1ccc(C#N)cc1 +COc1cccc(C(=O)CSc2nnnn2C2CCCC2)c1 +Clc1cccc(OCCCSc2nnnn2C2CC2)c1 +CC(C)(C)OC(=O)N1CCC(Nc2cccs2)C1 +CC1CN(C(=O)NCc2ccnc(-n3cccn3)c2)c2ccccc21 +COc1cccc(NC(=O)CCCC(O)c2cccs2)c1 +Cc1noc(CCC(=O)NC(c2ccccc2)C(C)(C)C)n1 +CCc1cnc(N)nc1N1CCC(CCC(=O)NC2CC2)CC1 +CN(Cc1ccc2c(c1)OCCO2)C(=O)CNC(=O)C(C)(C)C +Cc1noc(CNC(=O)C2CCN(C(=O)C(C)C)CC2)n1 +CC(C)Oc1ccc(C(=O)N2CCCC2(C)C)cn1 +Cc1csc(-c2cccc(NCc3ccc(S(C)=O)cc3)c2)n1 +Cc1ccccc1OCCSc1nnnn1C +Cc1cc(C(=O)OCC2CCCCO2)nn1-c1ccccc1 +COC1(C(Cl)(Cl)Cl)OC(=O)c2ccccc21 +O=C(Cn1c(=O)[nH]c2ccccc21)Nc1c(O)cccc1F +Cc1nc(C(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cs1 +CN(C)c1ccc(NC(=O)c2cccc(C(F)(F)F)c2)cn1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCCC1c1ccc[nH]1 +CC(C)CN1CCC2(CCN(C(=O)Cc3cccc(F)c3)CC2)C1=O +CN(C)c1ccc(C(=O)NCCNS(C)(=O)=O)cc1F +CCOCC1CCCN(C(=O)CCn2ncc(=O)c3ccccc32)C1 +CN(CCO)C(=O)Nc1ccn(-c2cccc(C(F)(F)F)c2)n1 +Cc1c(CNc2ccc(F)c(F)c2)c(=O)n(-c2ccccc2)n1C +COC(=O)c1ccc(C(C)N2CCC(C(N)=O)c3ccccc32)o1 +O=C(NCCNC(=O)C1CCC1)c1ccc(Br)cc1 +C=CCOc1ccc(C(=O)NCCN2CCOCC2)cc1N +CCC1CCCCN1C(=O)NCC(C)N1CCOCC1 +CC(=O)c1ccc(NC2CC(O)C(O)CO2)cc1 +COC(=O)CN(C)C(=O)c1ccccc1C(F)(F)F +CCCOc1ccc(C(=O)NCc2ccc(F)cc2)cc1N +Cc1nccn1-c1nc(N2CCOCC2)ncc1F +CCN(CC(=O)NC(C)(C)C)C(=O)c1cccc(C)c1C +CCN(CC)S(=O)(=O)c1cc(C(=O)Nc2ccn(C)n2)n(C)c1 +Cc1ccoc1C(=O)Nc1ccc(C(=O)N2CCOCC2)cc1 +Cn1cnnc1-c1cccc(NCc2csc(C(C)(C)C)n2)c1 +O=C(CCC1N=C(O)N(CCc2ccccc2)C1=O)NC1CC1 +O=c1ccc(-c2ccccc2)nn1CCn1nc2ccccn2c1=O +COCC(NC(=O)Nc1cnn(C(C)(C)C)c1)c1ccc(C)o1 +CC(=O)c1cc(C(=O)Nc2cccc3cccnc23)n(C)c1 +COC(=O)c1cc(NC(=O)c2ccco2)ccc1Cl +COc1ccc(CC(=O)NCCOc2ccc(N)c(C)c2)cc1 +CC(C)COC(=O)c1ccc(CCNC(N)=O)cc1 +CCOc1c(OC)ccc2c1CCNC2c1ccco1 +CCNC(=O)NC1CCN(C(=O)OC(C)(C)C)CC1 +CC(CO)C(C)NC(=O)Nc1cc(F)ccc1SCC(F)F +Cc1ccc(CC(=O)Nc2cc(N3CCCCC3)ncn2)cc1 +CCCN(CCC)C(=O)CS(=O)(=O)c1ccc(F)cc1 +Cc1cc2c(cc1S(=O)(=O)N1CCCC1)N(C(=O)C1CC1)CC2 +COc1cccc(-c2nnc(NC(=O)c3ccccc3C)o2)c1 +COc1ccc(CCNS(=O)(=O)N2CCOCC2)cc1OC +Cc1ccc(-n2ccnc2)c(C(=O)N(C)CC(=O)Nc2ccccc2)c1 +Fc1cc2c(c(F)c1Cl)CCNC2c1ccco1 +COc1ccc(NC(C)c2ccc(F)c(F)c2)cn1 +CC(C)COC(C)C(=O)N=c1[nH]nc(-c2ccccn2)[nH]1 +Cc1c(Cl)cc(C(=O)N2CCOCC2)c(F)c1F +CCc1sc(Cn2ccc(=O)[nH]c2=O)nc1-c1ccc(OC)cc1 +COC(=O)N1CCC(Sc2ncnc3ccccc23)CC1 +Cn1ccnc1C(=O)c1cccc(-c2cc(-n3cccn3)ncn2)c1 +COc1cccc(C(=O)N(C)c2ccccc2)c1OC +CC(=O)NCc1ccc(-c2csc(NC(=O)c3ccoc3)n2)o1 +Cc1nc2sccn2c1CNc1cccc(C#N)c1 +COc1ccc(C2C(C(=O)NC3CCCCC3)CCC(=O)N2C)cc1 +COc1cc(CN2CCc3nc(C)[nH]c(=O)c3CC2)cc(OC)c1 +Cc1c(C(C)NC(=O)c2ccc(-n3cccc3)cc2)cnn1C +COc1cccc(NCCC(=O)c2cccc(OC)c2)c1 +O=C(NC(c1ccccc1)C1CC1)c1cc(Cl)ccn1 +NS(=O)(=O)c1cccc(NC(=O)NCCCc2ccccc2)c1 +Cc1ccc(CNC(=O)NCc2cc(C)no2)c(C)c1 +CC(C)Cn1cc(NCc2ccc(-n3ccnc3)cc2)cn1 +COCC12CCCC1CN(C(=O)c1ccc(C)o1)C2 +CN(C(=O)Cc1ccn[nH]1)c1ccc(F)c(Cl)c1 +CCC(=O)NCCC1CCc2cc(Br)c(O)cc21 +COc1ccc(-c2csc(C3CC3)n2)cc1Cl +O=C(Nc1ccccc1)c1ccc(NCC(O)C2CC2)nn1 +CC1CN(CC(=O)NCCCc2ccccc2)C(C)CO1 +Cc1nc(C)c(C(=O)OCc2nc(C)c3ccccc3n2)s1 +Cc1nc(C(=O)N(C)c2nccs2)nn1-c1ccccc1C(C)C +CC(NS(=O)(=O)c1ccc(F)c(F)c1)c1ccccn1 +Cc1c[nH]c(=O)n1-c1ccc(C(=O)OC2CCCC2)cc1 +CCc1cc(C2CCCN2S(=O)(=O)Cc2ccccc2)on1 +NC(=O)CCCC(O)c1ccc(Br)cc1 +N#Cc1cc(NCc2nccn2Cc2ccccc2)ccc1F +Cc1ccc(NC(=O)C(C)Sc2nc(C)cc(=O)[nH]2)cc1 +Cc1cccc(NC(=O)CSc2nc(C)cc(C)n2)n1 +O=C(NCC1(O)CCOCC1)c1cccc(Br)c1 +CC(=O)c1c(C)[nH]c(C(=O)CSc2nnnn2C2CCCC2)c1C +Cc1cc(CSc2ncccc2C(=O)NC2CC2)no1 +COC(=O)CCS(=O)(=O)N=c1cc(C)c(N)c[nH]1 +CCCC(=O)Nc1cccc(NC(=O)N2CCN(C)C(CO)C2)c1 +O=C(C1CC1)N1CCC2(COCc3cnc(-c4cccnc4)nc32)C1 +COC(=O)c1cccc(O)c1C(=O)c1c(O)cc(C)cc1O +CC1CN(C(=O)NCc2cccc(COC(C)(C)C)c2)CCO1 +NC(=O)Nc1ccc(C(=O)NCCn2cccc2)cc1 +Cc1ccccc1OCC(=O)Nc1ccc(F)cc1F +Cc1ccc(CNC(=O)CSc2ccc(N)cc2)cc1 +Cc1[nH]ncc1C(=O)N(Cc1ccsc1)C1CC1 +CSc1ccc(C)c(C(=O)NC(C)c2ccncc2)c1 +O=C(Cc1ccccc1)Nc1nc(CC(=O)NC2CC2)cs1 +CC(C)CCOC1CCN(Cc2cc(C#N)cs2)C1 +Cc1ccc(CCNC(=O)c2cccc3c2SCCC3=O)cc1 +CC(C)Cc1nc(C(=O)NCc2cccs2)cs1 +Cc1cc(C)n2ncc(-c3noc(C4CC5CCC4O5)n3)c2n1 +COc1ccc(-c2noc(CNC(=O)NCc3ccco3)n2)cn1 +O=S(=O)(CCN1CCCCC1Cn1cccn1)c1ccccc1 +N#CC1CN(C(=O)c2cc3ccccc3[nH]2)CCN1Cc1ccccc1 +O=C(Nc1nnc(-c2ccc3c(c2)OCCO3)o1)c1ccc(F)cc1 +CCOc1cc(C)c(-c2ccc(C#N)c(=O)[nH]2)cc1C +Cc1ccc(C(O)CNC(=O)c2ccc(Cl)cc2)cc1 +CCCCOC(=O)c1ccc(Sc2nc(C)n[nH]2)c(N)c1 +CCCN(C)C(=O)NC1CCCc2c1cnn2C +CSc1nsc(NC(=O)c2ccccc2Br)n1 +CC(=O)c1ccc(NC(=O)N2CCCN(S(C)(=O)=O)CC2)cc1 +CCCCN(C)S(=O)(=O)NCc1cscn1 +CNC(=O)c1ccc(OCc2cccc(F)c2)cc1 +COc1ccc(CNC(=O)c2cnc3[nH]c(C(C)=O)cc3c2)cc1 +CC(=O)Nc1c(C#N)sc2nc3c(cc12)CCC3 +CSc1cccc(NC(=O)Cc2cn3ccsc3n2)c1 +C#Cc1cccc(NC(=O)COc2ccccc2C)c1 +COCCn1nnc2c(sc3nc(C)ccc32)c1=O +COc1cccc(CNC(=O)c2cccn2Cc2cccnc2)c1 +CC1CCCC(N(C)C(=O)c2ccc(=O)n(Cc3ccccc3)n2)C1 +CC(=O)Nc1cccc(C(=O)Nc2ncccc2CO)c1 +CC1CCC(NC(=O)C(Cc2ccccc2)NC(N)=O)CC1 +COc1ccc2[nH]cc(C(=O)c3ccc(C)cc3)c(=O)c2c1 +O=C(COc1cccc(F)c1)N1CCN(c2ncccn2)CC1 +O=C(c1ccc2nc(-n3cccc3)sc2c1)N1CCCCC1 +CCC(OC(=O)c1cc2ccccc2o1)C(=O)Nc1cc(C)on1 +CCCC1CC1NC(=O)c1cnc(C2CCCO2)s1 +O=C(Nc1cn[nH]c1)NC1C2CC3CC(C2)CC1C3 +Cn1cnc(CNC(=O)N2CCCCC2c2cc3ccccc3[nH]2)n1 +Cc1ccccc1C(=O)N1CCN(c2ccccc2O)CC1 +N#CCCn1c(C2CCC2)nc2cc(F)c(F)cc21 +Cc1cc(Cl)ccc1S(=O)(=O)Nc1cccc(C(N)=O)c1C +CC(Cn1cccn1)NC(=O)N1CCN(Cc2cccs2)CC1 +CC(C)Nc1cccc(CNC(=O)c2ccc(-n3ccnn3)cc2)c1 +CC(C)N(CC(F)(F)F)C(=O)c1ncccc1O +COc1ccc(CN2CC(C(=O)NCCNC(C)=O)CC2=O)cc1 +COc1cc(CC(=O)NC2CCN(C(=O)C(C)C)CC2)ccc1C +CC(C)c1cc(NC(=O)CSc2nc3ccccc3[nH]2)on1 +CC(NC(=O)NC1(c2cccc(Cl)c2)CC1)c1nncn1C +COCCNC(=O)C1CC2CN(c3ncccn3)CC2C1 +CC(C)CCc1noc(CN(C)Cc2nc3ccc(F)cc3[nH]2)n1 +N#Cc1ccc(NC(=O)CCCCn2cc(Cl)ccc2=O)cc1 +Cc1nc(C)c(-c2nn3c(C4CCC4)nnc3s2)s1 +O=C(c1cn[nH]n1)N1CCC2(CC1)CCN(c1ccccc1)C2=O +CCC1(CNC(=O)N2CCN(C(C)C(=O)N3CCCC3)CC2)CC1 +CCc1ccc(S(=O)(=O)NCc2cc3ccccn3n2)s1 +Cc1cc(N)cn2c(-c3cccc(Br)c3)nnc12 +CC1CN(CC(=O)c2cc3c(cc2Cl)OCO3)CC(C)O1 +COc1ccc(-n2cc(CNC(=O)c3c(C)nn(C)c3C)nn2)cc1 +N#CCCN(CCC(F)(F)F)C(=O)c1ccc2c(c1)OCC(=O)N2 +CCc1nnc(CN(CC)C(=O)CSc2nnc(C)s2)o1 +C=CCn1c(SCc2nc(N)nc(N)n2)nc2sccc2c1=O +COCc1cccc(C(=O)NCC(=O)NCc2ccco2)c1 +CCCC(=O)Nc1nnc(-c2ccc(S(=O)(=O)C(C)C)cc2)o1 +CCN(CC(C)C#N)C(=O)CCC(=O)c1ccc2c(c1)OCCO2 +O=C(c1cc(-c2cccnc2)on1)N1CCCC1c1ccsc1 +Cc1ocnc1C(=O)OCc1cccc(Br)c1C +Cc1nccn1Cc1cccc(CNC(=O)CCC(C)(C)C)c1 +Cc1cccc(C(=O)NC(C)C(=O)NC(C)c2ccccc2)c1 +COc1cc(Br)c(NC(=O)c2cnccn2)cc1OC +O=C(COc1ccc2ccc(=O)oc2c1)Nc1cccc(F)c1 +CC(C)n1nccc1NC(=O)CSc1ccc(F)cc1 +O=C(CSc1n[nH]c(=O)n1C1CC1)NCc1ccc(F)cc1 +CCc1cccc(CC)c1-n1ccnc1SCC(N)=O +Cc1csc(CNc2cnn(-c3ccc(C(F)(F)F)cc3)c2)n1 +CC(C)n1[nH]c(=O)c2c1N=C(O)CC2c1ccc2ncccc2c1 +Cc1ccc2cccc(OC(=O)c3cc4ccccc4oc3=O)c2n1 +CCC(OC(=O)c1ccc2nncn2c1)c1ccc(C)cc1 +CC(=O)Nc1ccc(OC(=O)c2cc3ccccc3[nH]2)cc1 +O=C(c1ccc(Cl)cc1)N1CCN(c2ccc3nncn3n2)CC1 +COCCc1nc2scc(-c3cc(C)ccc3OC)c2c(=O)[nH]1 +Cc1cc(F)ccc1NC(=O)N(C)CCN(C)C(=O)OC(C)(C)C +O=C(NCc1cscn1)c1ccccc1C(=O)c1ccc(F)cc1 +O=C(NCc1ccncc1)C1(c2ccccc2)CCCC1 +Cc1cc(C(O)Cn2cc(N)cn2)c(C)n1C1CC1 +COc1ccc(Cl)cc1N(C)C(=O)C1COc2ccccc2O1 +Cc1cc(C(F)(F)F)nn1CCNC(=O)C1CCCN(C(N)=O)C1 +CN1CCOc2ccc(NC(=O)c3ccncc3)cc2C1=O +Cn1c(=O)ccn(CC(=O)OCc2ccc(C#N)cc2)c1=O +Cc1csc(C2(NC(=O)Nc3ccc4c(c3)CCO4)CCC2)n1 +COc1cc(COC(=O)CN(C)C(=O)c2ccccc2)ccc1C +COc1ccccc1Cc1cn2ccc(C)c(N)c2n1 +CCCc1cc(NC(C)Cc2ccsc2)ncn1 +O=C(CCc1ccccc1)Nc1cccc2cn[nH]c12 +COc1cc(F)c(NS(=O)(=O)c2ccc(C)cc2)cc1F +N#Cc1ccc(NCC(=O)Nc2cccc(C#N)c2)cc1 +CC(Nc1nc(-c2ccncc2)nc2c1cnn2C)c1n[nH]c(=O)[nH]1 +CC(C)CCNC(=O)C1CCN(C(=O)c2ccoc2)CC1 +Cn1cc(C(=O)NCCOCCO)c(=O)c2c(N)cccc21 +Nc1c(C(=O)Nc2ccc(Cl)cc2)nnn1Cc1cccc(F)c1 +CC1=NC(C#N)C(C#N)=NC(c2c(F)cccc2Cl)C1 +O=C(NCCc1ccccc1)Nc1nnc(-c2ccsc2)o1 +Cc1cccc(NC(=O)c2nnn(Cc3ccccc3)c2C)c1 +CSc1ccc(CN(C)C(=O)C2CC(=O)N(C)C2)cc1 +Cc1ccc(C(O)CNS(=O)(=O)Cc2cccc(F)c2)o1 +Cc1csc(N(C(=O)c2cc3c(s2)CCC3)C2CC2)n1 +CC(=O)N1CCCN(C(=O)Cc2ccccc2Cl)CC1 +Cc1ccc(NC(=O)NCC(=O)Nc2ccccc2)cc1F +O=C(c1cc(F)c(F)c(F)c1)N(Cc1nccn1C(F)F)C1CC1 +COc1cccc(CNc2cnn(C)c(=O)c2Cl)c1 +O=C(c1c[nH]c2ccccc2c1=O)N(Cc1cccs1)C1CC1 +Cc1nc(CC(=O)NC2CCCN(c3ccccc3)C2=O)cs1 +COC(=O)Nc1ccc(S(=O)(=O)Nc2ccnc(C)n2)cc1 +Cc1cc(NCc2ccncc2)n2c(nc3ccccc32)c1C#N +COc1cc(C(=O)Nc2c(C)cc(C)nc2C)ccc1C +CC(=O)Nc1ccc(NC(=O)Cc2cn(C)c3ccccc23)cc1 +COc1ccc(-c2coc3cc(OC)c(OC)c(OC)c3c2=O)cc1 +COC(CCc1ccc2c(c1)NC(=O)C(C)O2)(OC)OC +O=C(Nc1cccnc1)c1cccc(C(=O)Nc2cccnc2)c1 +CC(C)NC(=O)CN(C)c1cccc2ccccc12 +Cc1nc(SCC(=O)NCc2ccncc2)c(C#N)c(C)c1C +CCNC(=O)c1ccc(C)c(NCC(=O)N(C)C2CCCCC2)c1 +CC(C)=CCC1(CO)CCCN(C(=O)c2cccc(O)c2)C1 +NC(=O)c1cc2ccccc2nc1C1CCCN(C(=O)C2CC2)C1 +CCc1sc(C(=O)N(C)CCCC(=O)OC)cc1C +Nc1cccc(Cc2nccn2CC(F)(F)F)c1 +CC(C)c1cccc(NC(=O)N(C)Cc2ccccn2)c1 +CN(Cc1cc(Br)cs1)C(=O)c1cc(F)ccc1N +O=c1cccnn1CCNS(=O)(=O)c1ccc2c(c1)OCCO2 +Cn1nc(C(=O)N2CCOCC2)cc1NC(=O)c1ccccc1Cl +Cc1cccc(C(=O)N2CC(C)Sc3ccccc32)n1 +N#Cc1ccc(OCC(=O)Nc2nccs2)cc1 +CC(C)C1(O)CN(C(=O)c2cnc(C3CC3)nc2)CC1C +CCOc1cc(CNS(N)(=O)=O)ccc1OC(F)F +COc1ccc(F)cc1C(=O)CNc1ccccc1 +Cn1cc(NC(=O)c2cc(=O)n(C)c3ccccc23)cn1 +CC(=O)NCCCc1nc(C2CC2)nn1C(C)(C)C +Cc1cc(C2CCCN2C(=O)c2ccc(-c3ccccc3)[nH]c2=O)no1 +COCCS(=O)(=O)N1CCC(OCc2ccccc2C)CC1 +Cc1ccc(C2CN(C(=O)NCCCc3c(C)noc3C)CCO2)o1 +CC(c1nc(-c2ccco2)no1)n1nnc(-c2cccc(F)c2)n1 +CCOC(=O)C(Cc1nc2ccccc2n1O)NC +Cc1ccc(C(O)CNC(=O)c2cc3ccccc3oc2=O)o1 +CC(NS(=O)(=O)c1ccc(C#N)cc1)c1cccc(Cl)c1 +COc1ccc(CNc2ncc3c(n2)CC(C)(C)CC3=O)cc1 +CCN(CCNC(=O)c1ccc(F)cc1)C(=O)c1ccc(F)cc1 +N#CCCN(CCC#N)c1ncnc(N2CCCCCC2)c1N +NC(=O)C1CCN(C(=O)c2cc3ccccc3o2)c2ccccc21 +CCC1Nc2cc(Cl)ccc2N(CCCC(N)=O)C1=O +CC(C)C(C#N)N(C)C(=O)COc1ccc(Cl)cc1 +CSc1ccccc1NC(=O)CN(C)C(=O)c1cccc(Cl)c1 +CC(C)(O)C1NCCc2ccc(OC(F)(F)F)cc21 +O=C(c1ccccc1-n1cnnn1)N1CCN(c2ccccc2)CC1 +Cc1cc2c(=O)n(C)c(=O)n(CCc3ccccc3)c2s1 +CCOc1ccccc1N1CCN(C(=O)c2cc(F)ccc2F)CC1 +Cc1csc(CN2CCCC(C(=O)N3CCOCC3)C2)n1 +Cn1cnc2cc(CCC(=O)Nc3ccc4c(c3)COC4=O)ccc21 +Cc1cc(=O)c(O)c(CN(C)C)n1Cc1ccc(F)cc1 +COc1cc(CN2CCOCC2C2CC2)cc(OC)c1 +CC1Oc2ccc(C(O)CCCCO)cc2N(C)C1=O +O=S(=O)(CCn1nnc2ccccc21)NC1CCCCCC1 +COCCNC(=O)c1cc(-c2ccc(Cl)cc2Cl)on1 +NC(=O)c1cnc(NCc2nc3ccccc3s2)c(Cl)c1 +Cc1cc(C)cc(NC(=O)c2cnc3[nH]nc(C)c3c2)c1 +CNC(=O)COC(=O)C(C)c1ccc2cc(OC)ccc2c1 +Cc1nn(-c2ncc(CO)cc2Cl)c(C)c1Br +COc1ccc(S(=O)(=O)N2CCN(c3ccccc3)CC2)c(C)c1 +O=C(NCc1cccnc1)c1cc2n(n1)CCCO2 +Cc1ccc(OCC(=O)Nc2ccccc2-c2nc(C)no2)cc1 +CCN(CCO)C(=O)c1cc(=O)c2ccccc2[nH]1 +COc1cccc(OCC(=O)NCc2ccccn2)c1 +Cc1nonc1NC(=O)c1ccc(Cl)c(Cl)c1 +CC(C)N(CC(N)=O)C(=O)C(C)(C)c1cccc(Cl)c1 +COc1ccccc1NC(=O)c1ccc2c(c1)NC(=O)C1CCCN21 +COc1cc(CNC(=O)CN(C)C(C)=O)ccn1 +COC(=O)c1ccc2cccc(N3CCOCC3)c2n1 +COc1ccc(C(=O)NCCCO)cc1Br +O=C(NCc1ccnc(OC2CCC2)c1)c1cc(Cl)c[nH]1 +Cc1c(C(=O)OCC2CC2)nnn1-c1ccc2ncccc2c1 +Cn1c(=O)c(C(=O)N2CC3C4CCC(C4)C3C2)nc2ccccc21 +COC(=O)c1ccc(OCC(=O)c2ccc3c(c2)CCC3)c(OC)c1 +O=C(COc1ccc(F)cc1)Nc1ccc2c(c1)COC2 +O=c1ccc(S(=O)(=O)N2CCC(Cc3ccccc3)CC2)c[nH]1 +CCc1nc(CNCCc2cccc(C(=O)NC)c2)cs1 +CC(C(=O)Oc1ccc(C(=O)N2CCCC2)cc1)c1ccsc1 +COC(=O)CNCc1c[nH]c2cc(Cl)ccc12 +COCC(=O)N1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1 +Cc1nn(C)c(C)c1CC(=O)Nc1cccnc1-n1cccn1 +O=C(Cc1ccccc1F)Nc1cc(-c2ccsc2)no1 +COc1ccc(CN(C)C(=O)c2cccc(C)c2)c(OC)c1 +Cc1ccc(NC(=O)COc2ccccc2O)cc1C(F)(F)F +O=C(c1cccc(F)c1)N1CCC2(CC1)OCCCO2 +Cc1ccccc1CNS(=O)(=O)c1cnn(C(C)C)c1 +COC(=O)c1ccc(N2CCCC2)c(NC(=O)c2cccc(C)n2)c1 +CC(=O)Nc1ccc(S(=O)(=O)N2CCNC(=O)CC2)cc1 +Cc1cccc(CNC(=O)Nc2cccc(N)c2)n1 +COC(=O)C1CCN(C(=O)c2ccc(N(C)C)nc2)c2ccccc21 +CCCNC(=O)Cn1nc(-n2cccn2)ccc1=O +CC1CC1C(=O)C(C#N)c1nc(-c2ccc(C#N)cc2)cs1 +Cc1cc(S(C)(=O)=O)ccc1NC(=O)c1cscn1 +Cn1cc(C(=O)NCc2ccc(=O)[nH]c2)c(C(C)(C)C)n1 +Cc1ccc2c(n1)OCCN2C(=O)c1cnn(C)c1C +CCn1cc(S(=O)(=O)NC2COc3c(cccc3OC)C2)cn1 +Cc1sc2ncnc(SC(C)C(=O)N3CCCC3)c2c1C +C#CCOC(=O)c1ccccc1C(=O)NCc1ccccc1 +Cc1ccc(OCC(=O)NCc2ccc3c(c2)OCO3)c(C)c1 +CCN(CC)S(=O)(=O)CCNC(=O)N1CCC2CCCCC21 +Cc1cc(C(=O)N2CCCCCC2c2nn(C)cc2Cl)on1 +COC(=O)Nc1ccc(NC(=O)C2CC3C=CC2C3)cc1 +CCS(=O)(=O)N1CCC(C(=O)c2ccc(CC(C)C)cc2)CC1 +CCCc1cc(C(=O)N(C)Cc2n[nH]c3c2CCCCC3)n(C)n1 +Cc1nc(SCC(=O)Nc2ccccc2O)[nH]c(=O)c1CCO +CCN1C(=O)CCC2(CN(C)C(=O)Cc3cccc(F)c3)CCCC12 +CC(C)c1nc2ccc(NC(=O)c3csnn3)cc2s1 +COC(=O)c1sc(Cc2ccc(F)cc2)nc1C +Brc1cnn(-c2ccc3[nH]cnc3c2)c1 +Cc1ccc(NCc2nc3nc(C)cc(C)n3n2)cc1 +CNC(=O)C1CCCN(C(=O)c2cc(OC)c(OC)cc2C)C1 +CCNC(=O)c1ccc(N2CCCC(c3nccs3)C2)nn1 +CC(C)C(CNC(=O)c1ccc(F)cc1F)N1CCOCC1 +CCn1cc(C(=O)Nc2cc(C)cc(C)c2)c(=O)c2ccc(C)nc21 +COC(=O)CCCc1csc(NC(=O)c2cccc(F)c2F)n1 +COC(=O)CC(NC(=O)c1sc(C)nc1C)c1ccc(OC)cc1 +CC1CN(C(=O)c2ccc(Cn3cccn3)o2)CC(C)O1 +CC(NS(=O)(=O)c1cn[nH]c1)c1ccc(Cl)c(Cl)c1 +N#CC1(NC(=O)CCc2ccc(OC(F)(F)F)cc2)CCC1 +COC(OC)(OC)C(C)(C)c1ccc2c(c1)OCCCO2 +O=C(Nc1cccc(F)c1)N1CCN(C(=O)C2CCCCC2)CC1 +CCN(c1ccccc1)S(=O)(=O)Cc1ccccc1 +Cn1nc(C(=O)N2CC(c3ccccn3)C2)c2c1CCCC2 +COC(=O)c1cc(C(=O)N(C)C(C)c2cc3ccccc3o2)ccn1 +Cn1ncc2c(N3CCN(C(=O)C4(C#N)CCCC4)CC3)ncnc21 +COC(=O)c1ccc(S(=O)(=O)N(C)c2cccc(C#N)c2)o1 +O=C(Nc1cc(F)ccc1Cl)c1ccc(Cn2ccnc2)cc1 +COCCOc1ccccc1C(=O)N1CCC(O)(C(F)(F)F)CC1 +O=C(Cc1nnc(-c2ccsc2)o1)NCc1cccc(Cl)c1 +N#Cc1cccnc1NCC1(c2cccc(F)c2)CCOCC1 +CC(C)c1nc(C2CCCN2C(=O)c2cc3c(s2)CCC3)no1 +O=C(CCc1ccccc1)N1CCc2[nH]c3ccnn3c(=O)c2C1 +Cc1ccc(CC(=O)NCCCNS(C)(=O)=O)cn1 +CCSc1cc(Cl)ccc1C(=O)NC(C)Cn1cncn1 +OC(Cc1cccnc1)(Cc1cccnc1)c1cc2ccccc2[nH]1 +Nc1ccccc1NC(=O)CCCSc1ncn[nH]1 +CC(=O)NC(CC(=O)Oc1ccc(C(C)=O)cc1)c1ccccc1 +CC(C)NC(=O)c1ccc2nc(-n3cccc3)sc2c1 +Cc1cc(C)n(-c2nc(CCNC(=O)c3cc(C)oc3C)cs2)n1 +Cc1ccc(NC(=O)c2ccc(S(=O)(=O)N(C)C3CC3)cc2)cc1 +Cc1ccc(S(=O)(=O)Oc2cccc(F)c2)cc1 +Cc1ncc(CNC(=O)Nc2ccccc2C(C)C)s1 +CCc1nc2n(n1)CCCC2NC(=O)NC(C)c1ccc(C)cc1 +COCCN(C)C(=O)NCc1ccnc(OC(C)(C)C)c1 +COc1cc(CNC(=O)NCC(C)Nc2ccccc2)ccn1 +CCOC(=O)CCCNC(=O)c1n[nH]c2ccc(C)cc12 +CCOC(=O)c1csc(NC(=O)Cc2csc(CC)n2)n1 +CCc1cc(NC(C)c2nc(CC)no2)nc(N2CCOCC2)n1 +CCOc1cc(C)ccc1NC(=O)CC(NC(N)=O)c1cccs1 +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccc(N2CCCC2)nn1 +Oc1ccc2cc(CNc3cnns3)ccc2c1 +N#CCOc1cccc(CC(=O)OCC2CCCCO2)c1 +CC(C)c1noc(-c2cccc(Cn3cccn3)c2)n1 +COc1cccc(C(=O)CN2CC(C)OC(C)C2)c1 +N#CCCN(C(=O)CSc1nc2ccccc2[nH]1)c1ccccc1 +O=C(Nc1nc(C2CC2)cs1)c1ccn(-c2ccc(F)cc2)n1 +Cc1csc(SCCn2c(=O)oc3ccccc32)n1 +CCOC(=O)c1c(C)nc(C)c(C(=O)OCC)c1-c1ccncc1 +Cc1csc(NC(=O)NC2CCCC(C(F)(F)F)C2)n1 +Cc1cccn2c(CN3CCN(C(C)C(N)=O)CC3)cnc12 +CC(=O)N1CCCC(C(=O)N2CC(OCc3ccccc3)C2)C1 +O=C(C1CC1)N1CCCC(c2ncncc2-c2ccncc2)C1 +Cc1ccc(CNC(=O)Nc2ccc(Oc3cccnc3)nc2)s1 +CC1CCN(C(=O)CNc2cccc(OC(C)C)c2)CC1 +CC(N)c1cc(=O)n2nc(-c3ccc(Cl)cc3)cc2[nH]1 +O=C(NCC1CCCO1)Nc1nnc(Cc2ccc(F)cc2)s1 +O=C(NCc1cccnc1)c1nn(-c2ccccc2F)nc1CO +O=C(Cn1ccc2ccccc2c1=O)Nc1ccc2c(c1)OCCO2 +C=CCNC(=O)CN1CCN(C(=O)Nc2cc(F)cc(F)c2)CC1 +CC(C)Sc1ncccc1C(=O)NCCCC(N)=O +CSc1cncc(NCC2CCN(C(=O)c3ccccc3)CC2)n1 +O=C(COCC1CC1)NC1CCCN(c2ncccn2)C1 +Cc1cc(C)n(CC(=O)N2CCOCC(CO)C2)c(=O)n1 +CCn1ncc2cc(C(=O)NCCC(C)C)c(N)nc21 +CC(C)c1cc(C(=O)N2CCCC2)nc(N2CCOCC2)n1 +Cc1cccc(C2(C(=O)Nc3cc(F)cc(S(N)(=O)=O)c3)CC2)c1 +OCCc1nnc(CCOc2ccc3ccccc3c2)o1 +O=C(Cc1cc(-c2ccccc2)on1)NCc1ccncc1 +O=C(NCCc1cccs1)NC1CCN(CC(F)(F)F)C1 +N#Cc1c(N2CCCC2)c2ccc3c(c2oc1=O)OCCO3 +COC(=O)CCCS(=O)(=O)N1CCCc2ccccc21 +O=S(=O)(NCc1ccc(C(O)c2cccs2)s1)C1CC1 +c1ccc(-c2cc(CN3CCOCC3C3CC3)n[nH]2)cc1 +CNC(=O)c1ccc(NC(=O)NC(C)CCC(C)(C)C)cc1 +Cc1ccc(C(=O)OCC(=O)N2CCCC2)c(C)c1 +COc1ccc(OC)c(C(C)NC(=O)c2cn(C)nc2C)c1 +COc1ccc(C(=O)N2CCC(C)(O)C(O)C2)cn1 +CCOC(=O)CCN(C(=O)C1COCCO1)C1CC1 +Cc1nc(SCC(=O)NC2CCCC2)c2c(C)c(C)sc2n1 +CN(Cc1cnn(C)c1)C(=O)c1ccc(Cl)c2cccnc12 +CCOC(=O)c1cnc(CC)nc1-c1ccccc1Cl +c1cc(N2CCCCC2)ccc1-c1noc(Cn2cnnn2)n1 +O=C(Cn1ccc2ccccc21)NCCc1ccsc1 +CCC(NC(=O)CCCn1cncn1)c1cc(F)ccc1F +O=C(NCc1ccc(F)cc1)C1(c2cc(-c3cccs3)on2)CC1 +Cc1nc(C(=O)N2CC(C)Cc3ccccc32)cs1 +CCOCCS(=O)(=O)Nc1[nH]nc2ccccc12 +Cc1cc(F)cc(NC(=O)N2CCOC(C)C2C)c1 +CN(Cc1ccc(SC(F)F)cc1)c1cncc(C(N)=O)n1 +CC(=O)c1cccc(NC(=O)Nc2cc(-c3ccccc3)n[nH]2)c1 +CC(C)C(NC(=O)NCc1cccs1)c1nc2ccccc2[nH]1 +O=C(NCCCNC(=O)C1CC=CC1)c1cccs1 +O=C(NCc1ccccc1)c1c[nH]c2cccc(F)c12 +CCc1ocnc1C(=O)N1CCCC(COc2cccc(F)c2)C1 +Cc1ccc(S(=O)(=O)N2CC3(COC(C)(C)OC3)C2)s1 +CC(C)CC(NC(=O)c1ccc(C#N)cc1)C(=O)N(C)C +Cc1cc(N)ccc1NC(=O)COc1c(C)cccc1C +Cc1ccccc1OCC(=O)c1ccc(C2OCCO2)cc1 +NC(=O)NCC(=O)NC1CCSc2ccc(F)cc21 +Cc1ccc(NC(=O)c2ccc3cc[nH]c3c2)cc1-n1cnnn1 +O=C(Nc1ccccc1CN1CCc2ccccc21)c1cc[nH]n1 +Cc1ccc(-c2nc3cc4c(cc3n2CC#N)OCO4)cc1N +CC(C)S(=O)(=O)Nc1ccc2c(c1)OCC(C)(C)C(=O)N2 +NC(=O)c1ccc(NC(=O)NCc2ccccc2F)cc1 +CS(=O)(=O)NC1CCN(C(=O)NC2CCc3ccccc32)CC1 +CCCNC(=O)Nc1cccc(NC(=O)OCC)c1C +Cc1ncsc1CCOC(=O)CCN1C(=O)COc2ccccc21 +Cc1ccc(-c2cc(CNC(=O)NCC3CCOC3)on2)cc1 +CC(NC(=O)COc1ccc(S(C)(=O)=O)cc1)c1ccccc1 +CCSc1nnc(C(NC(=O)OC(C)(C)C)C(C)C)o1 +COc1cccc(C(CNC(=O)c2c(F)cccc2F)OC)c1 +O=C(c1cccc2c1OCCO2)N1CCN(c2ccc(O)cc2)CC1 +CCCNC(=O)C(C)Nc1ncccc1C(N)=O +C#Cc1ccc(C23OCC(C4CC4C)(CO2)CO3)cc1 +CCC(C)n1ncc(C(=O)Nc2ccc3oc(C)nc3c2)c1C1CC1 +Cc1ccc(OCC(=O)N=c2[nH]nc3cc(C)ccn23)c(C)c1 +O=C(c1cccs1)N1CCN(c2ccc3nncn3n2)CC1 +Cc1cccc(C(=O)NCCC(=O)N(Cc2ccccc2)C(C)C)c1 +CNc1ccc(Nc2ccc(Cl)c(C#N)n2)cn1 +CC(C)N(CC(F)(F)F)C(=O)COc1ccc(C(N)=O)cc1 +N#Cc1ccc(Cl)cc1S(=O)(=O)N1CCN(CC(F)F)CC1 +Cc1[nH]c2ccccc2c1C(=O)NCc1cccc(Cn2ccnc2)c1 +O=C(CCn1ncc2ccccc21)NCCc1ccco1 +COc1ccc(-c2ccc(CO)o2)cc1NC(=O)c1ccc(F)cc1 +COc1cccc(-c2n[nH]c3c2CN(C(=O)c2ccsc2)CC3)c1 +COc1ccc(Oc2cc(CNC(=O)c3cnns3)ccn2)cc1 +Cc1cc(C)n(-c2ccc(C(=O)NC(C)c3ccc(C)o3)cc2)n1 +Nc1nc(N2CCCC2)ncc1C(=O)N1CCOCC1 +Cc1cccc(C)c1NC(=O)CSc1nnnn1C1CCCCC1 +Cc1ccccc1C(=O)NCC(O)c1cn(C)c2ccccc12 +C=CCn1c(C)nnc1SCC(=O)Nc1ccccc1C +O=c1c(Cl)c(Cl)cnn1Cc1cccc2cccnc12 +CCN(CCO)C(=O)NCC1(N2CCOCC2)CCCCC1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)n(C)c(=O)n3C)nc1 +Nc1c(C2CC2)n[nH]c1C(=O)NCC1CCCCC1 +Cc1cc(CCC(=O)N2CCc3[nH]ncc3C2)ccc1Br +CC(OC(=O)c1c(F)cccc1Cl)C(=O)Nc1ccccc1C#N +CN(Cc1cccc(C#N)c1)C(=O)c1cnc(C2CCCO2)s1 +Cc1cc(S(=O)(=O)NCC(C)O)ccc1Br +O=C(Cc1ccc[nH]1)NCC1(c2cccc(Br)c2)CCC1 +Cn1nnnc1SCC(=O)Nc1cc(C(N)=O)cc(C(N)=O)c1 +COc1cc(OC)c(NC(=O)NC(CCO)C(C)C)cc1F +COc1ccc(CNC(=O)Cc2c(C)nc(C)[nH]c2=O)cc1OC +NC(=O)c1ccc(OCC(=O)NCC2COc3ccccc3O2)cc1 +CC(=O)N1CCN(C(=O)c2cc3ccccc3[nH]c2=O)CC(O)C1 +O=C(COC(=O)C1CC2C=CC1C2)NCc1ccco1 +Cc1noc(CCNC(=O)c2cc3c(s2)CCC(C)C3)n1 +CCN1CCC2(CCN(C(=O)N3CCCC3)CC2)C1=O +CN(CCN(C)S(=O)(=O)N(C)C)c1ccccc1 +COC(=O)c1c(C)nn(-c2ccc(C)cc2)c1-n1cccc1 +CC(=O)c1sc(NCc2ccc(Cl)cc2)nc1C +COC(=O)CCNC(=O)COc1ccc(F)cc1Cl +Cn1cnnc1CCNC(=O)c1ccccc1Oc1ccccc1C#N +CCCNC(=O)Cn1c(=O)ccn(Cc2ccccc2C)c1=O +CC(C)(C)c1noc(COc2ccc3ccc(=O)oc3c2)n1 +CN(C)C(=O)CCNC(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +CCc1onc(C)c1NC(=O)c1c(C)c2ccccc2oc1=O +CC1Cc2cc(-c3cc(CC(=O)NCc4cccnc4)no3)ccc2O1 +CCOCc1cccc(CNC(=O)CNC(N)=O)c1 +O=C(Cc1cccc(F)c1F)NCCNC(=O)c1ccccc1 +O=C(c1nnc2sc(-c3ccc(Cl)cc3)nn12)N1CCCCC1 +COc1ccccc1OCC(=O)Nc1ccccc1C +CC(=O)Nc1cc(NC(=O)CCSc2ccccn2)ccc1Cl +CCOc1ccc(NC(=O)NCc2ccc(OC)c(F)c2)cc1 +CC(C)(CNC(=O)c1ccsc1)N1CCOCC1 +N#CCCn1c(C(F)(F)F)nc2cccc(F)c21 +N#Cc1c(N2CCOCC2)nsc1-c1cccnc1 +Cc1nc2ccccc2nc1SC1CCCCNC1=O +Nc1cncc(C(=O)Nc2ccc(Cl)c(Cl)c2)c1 +CN(C1CCCCC1)S(=O)(=O)c1ccc2c(c1)CCCC(=O)N2 +Cn1cccc1C(=O)NCc1ccccc1-n1cccn1 +COCCCn1c(SCc2nc3ccccc3s2)n[nH]c1=O +O=C(NCc1nc(-c2ccncc2)n[nH]1)c1ccc(Cl)cc1Cl +C#CCCN1CCN(C(=O)Cn2cnc3ccccc3c2=O)CC1 +CCOc1ccc(C(=O)NCC(=O)Nc2cccc(C)c2)cc1 +CCC(C)(C)C1CCC(NC(=O)c2cccnc2)CC1 +CC(Sc1nnnn1C1CC1)C(=O)N1CCCc2ccccc21 +CCC(C)(C)NC(=O)CSc1nnnn1-c1cccc(C)c1C +N#CCSc1cccc(C(=O)N2CCc3ccc(Cl)cc3C2)c1 +CN(C)C(=O)c1ccc2c(c1)CCN2C(=O)C1COc2ccccc21 +CN(Cc1ccc(C(N)=O)cc1)c1c(F)cccc1F +CC(C)(C)NC(=O)NCC#Cc1cccc(Cl)c1 +CC(CCCO)NC(=O)NC1c2cccc(F)c2CCC1C +CCc1nc2n(n1)CCCC2NC(=O)c1ccc(N(CC)CC)cc1 +CC1CN(C(=O)Nc2cccc(C(N)=O)n2)C2CCCCC12 +COc1ccc(NC(=O)c2ccncc2F)c(O)c1 +Cn1cc(NC(=O)N2CCN(Cc3noc(C4CC4)n3)CC2)cn1 +O=C(NC1CNCc2cccc(Cl)c21)C1CCCCC1 +Cn1nccc1C(=O)NCCC(=O)N1CCCCC1 +Cc1cc(N)nc(SCCC(=O)Nc2cc(F)cc(F)c2)n1 +N#CCCN(Cc1ccc2ccccc2n1)C1CCOCC1 +Cc1cc(NC(=O)COC(=O)c2cc(=O)c3ccccc3o2)no1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCc1cc2ccccc2[nH]1 +O=C(CSc1ccc(Br)cc1)NC1CCCNC1=O +Nc1cc(F)cc2c1CCNC2C1=CC(O)C(O)C(O)C1 +COc1ccc(-c2nc(C#N)c(NCC(C)C)o2)cc1OC +O=C(COc1cccc2c1NCCC2)Nc1ccccc1F +Cc1cc(C(=O)NCCCn2nc(C)cc2C)on1 +COc1cccc(F)c1C(C)Nc1ccc2nnc(C3CC3)n2n1 +Cc1oc(-c2ccc(F)cc2F)nc1CN1CCN(C)C(=O)C1C +CC(C)NC(=O)C1CC(=O)N(c2ccccc2Br)C1 +CCN(CC)c1ncnc(N2CCN(c3ccccc3)CC2)c1N +COc1ccc(NC(=O)c2cc(-c3ccco3)on2)cc1 +COC(=O)CSc1cc(N2CCCC(C)C2)ncn1 +Cc1ncsc1CN(C)c1nnc(C)c(C)c1C#N +Cn1cnnc1C1CCCN(Cc2cccc3cn[nH]c23)C1 +Cc1ccccc1NC(=O)NC1CCOc2c(Cl)cccc21 +CC1CC(C)CN(c2ccc(S(=O)(=O)N3CCOCC3)cc2)C1 +CC(Cc1ccccc1F)C(=O)N=c1[nH]nc2ccccn12 +Cc1cnn(-c2ccncc2NCc2cnc3c(cnn3C(C)C)c2)c1 +CCCNc1ccc(Cl)cc1NC(=O)C(C)n1cncn1 +NC(=O)c1ccc(Cl)cc1NC(=O)Cc1cccc(F)c1F +CCNC(=O)CN1CCN(C(=O)c2ccc(C(C)C)[nH]c2=O)CC1 +NC(=O)c1ccc(CNc2ccc(Cl)c(Cl)c2)cc1 +N#Cc1cccc(C(=O)N2CCN(CCn3cccn3)CC2)c1 +COCCOc1ccc(NC(=O)c2ccc(OC)c(F)c2)cc1F +COc1cc(CNC(=O)CC2C=CCC2)ccc1C +O=C(NCc1cccnc1)NCc1ccccc1Cl +CCN(CC(F)(F)F)C(=O)c1cccc(CN2CCCC2=O)c1 +CC(C)CCn1c(=O)c2ccccc2n(CC(=O)NC(C)C)c1=O +CC(C)CN(C(=O)CN1CCN(S(C)(=O)=O)CC1)C1CC1 +NC(=O)c1ccc(NC(=O)NC2CCCC(C(F)(F)F)C2)cn1 +Cc1ccc2c(CC(=O)Nc3ccn(C)n3)coc2c1 +CSc1ccccc1NC(=O)CSc1ccccn1 +CC(C(=O)NCCCc1ccccc1)N1Cc2ccccc2C1=O +CC(=O)Nc1cccc(Oc2ccc(N)cc2Cl)c1 +O=C(CSc1nncs1)c1ccc(Br)cc1 +COCC(=O)N1CCCC(c2ccnc(-c3ccccc3)n2)C1 +C=CCNC(=O)c1cc(OC)c(Br)c(OC)c1 +Cc1csc(Cn2ccc(-c3ccc(F)cc3)n2)n1 +OCCc1nnc(CCOc2ccc3c(c2)CCC3)o1 +CC(C)(C)OC(=O)N1CCC(NC(=O)c2ccccc2N)CC1 +Cc1ccc(-c2cc3nc(CC(=O)NC(C)C)[nH]c(=O)c3s2)cc1 +Cn1ncc(C(=O)NCC2(Sc3ccccc3)CCCC2)c1N +Cc1sc(-c2ccco2)nc1C(=O)N1CCC(CO)CC1 +COC(=O)N1CCCC(NC(=O)NCc2ccc(C)nc2)C1 +CCC(NC(=O)NCc1ccc(C)nc1)c1nc(C)cs1 +Clc1ccc(Cn2cc(Nc3ncnc4[nH]ncc34)cn2)cc1 +CC(C)Cc1nnc(C(C)N2CCN(Cc3cccs3)CC2)o1 +Cc1cc(Br)ccc1OCc1nsc(N(C)C)n1 +COc1ccc(F)cc1S(=O)(=O)NC(C)COc1ccccc1 +CC(C)(C)CCNC(=O)COc1ccccc1C#N +CCc1ccc(NCc2ccc(C(N)=O)cc2F)cc1 +Cn1cc(C(=O)N2CC(C)(C)C2(C)C)c(C(C)(C)C)n1 +COC(C(=O)Nc1ccc(C#N)cc1Br)c1ccccc1 +CN(CCOc1ccccc1)C(=O)CCn1ccccc1=O +O=C(Nc1ccccc1O)c1cccc(NC(=O)c2ccco2)c1 +CC(C)(C)c1ccc(NC(=O)N2CCOCC2C2CC2)nn1 +COC(=O)c1sccc1NC(=O)CN1C(=O)COc2ccccc21 +CC(=O)NC(C(=O)OCC(=O)N1CCCc2ccccc21)C(C)C +CCC1CCc2sc(C(=O)N3CCN(C)CC3)cc2C1 +Cc1cc(N(C)C)nc(C2CCCN(S(C)(=O)=O)C2)n1 +Cc1ncccc1NC(=O)c1cccc(Nc2cnn(C)c2)c1 +Cc1cc(N)c(S(=O)(=O)NC(C)C(N)=O)cc1C +O=C(Cn1cnc2sccc2c1=O)Oc1ccccc1 +CCCOc1cccc(NCC(=O)NC(C)C)c1 +CC(C)c1ccccc1NC(=O)C1CN(C(=O)c2cnccn2)C1 +NC(=O)CNC(=O)c1nc(-c2cccs2)n(-c2cccc(F)c2)n1 +CC(C)(C(=O)Nc1cc(F)ccc1F)c1ccc(N)cc1 +COc1ccccc1CC(=O)N(C)Cc1sccc1C +CCOC(=O)Nc1nnc(SC(C)CC)s1 +Cc1nc(C2CCCN(C(=O)c3ccnc(N(C)C)c3)C2)no1 +COc1ccc2oc(=O)c(S(=O)(=O)N3CCCCC3)cc2c1 +CCc1noc(CC)c1CC(=O)N(C)Cc1nc2c(s1)CCCC2 +CN(Cc1cccc2ccccc12)C(=O)CSc1ccncc1 +O=C(NC1CC1)C1CC(=O)N(c2cccc(Cl)c2Cl)C1 +COc1ccc(CC2(c3ccccc3)NC(N)=NC2=O)cc1 +CCC1CCCCCN1C(=O)c1ccc2[nH]c(C)nc2c1 +COC(=O)C(C)NS(=O)(=O)c1cc(C)ccc1F +CC(C)C(C)NC(=O)CC1OC(=O)c2ccccc21 +CCOc1ccc(C(=O)NC2(C#N)CCCCC2)cc1OCC +Cc1c(NCCOc2ccccc2F)cccc1N1CCCC1=O +Cc1cccc(OCCN(C)S(=O)(=O)N(C)C)c1 +Cc1oc(CO)cc1C(=O)OCc1cc(=O)n2cc(Cl)ccc2n1 +COCCNC(=O)N(Cc1ccccc1C(F)(F)F)C1CC1 +COC(=O)CNC(=O)C1CCN(c2nc3ccccc3s2)CC1 +O=C(COc1ccccc1)N1CC2CCC1C2Oc1cccnc1 +O=C(Cn1c(CO)nc2cc(Cl)ccc21)N1CCCC1 +COc1cccc(C(=O)OC(C)C(=O)N2CCc3ccccc3C2)c1 +Cc1ncc(C(=O)NC2CCCCCC2)c(C)c1N +CCC(=O)Nc1ccc(SCC(=O)Nc2ccc(F)cc2)nn1 +O=C(NCc1nccn1C(F)F)c1ccnc(OC2CCC2)c1 +O=C(c1cc(C2CC2)on1)N1CCOc2ccccc21 +COCCN1CCN(C(=O)NCC2(c3ccccc3)CC2)CC1=O +COc1cc(CNC(=O)NCCOc2ccc(Cl)cc2)ccn1 +CCc1onc(C)c1NC(=O)c1cnn(C(C)(C)C)c1 +CCOC(=O)C1=C(C)NC(=O)NC1c1c[nH]c2ccccc12 +O=C(CCNS(=O)(=O)c1cccc(Cl)c1)NCCO +C#CCN1CCN(C(=O)c2cncc(Br)c2)CC1 +Cc1ccc(N)c(OCC(=O)Nc2ccccc2C)c1 +N#Cc1cccnc1N1CC=C(c2ccc(O)cc2)CC1 +Cc1cccc(CCNCc2cccc(C#N)c2)c1 +CS(=O)(=O)N1CC2CCCC2(COc2ccccn2)C1 +N#Cc1ccc(N2CCN(C(=O)c3ccc(F)cc3Cl)CC2)nc1 +CNc1ccc(S(=O)(=O)N2CCC(O)CC2)cn1 +COC(=O)c1nnc2sc(-c3cccc(Cl)c3)nn12 +CN(C)C(=O)CN(C)S(=O)(=O)c1cccc(F)c1C#N +CCCc1nnc(NC(=O)Cn2nnc(-c3ccc(C)cc3)n2)s1 +CCCCN(C(=O)C1CC1C)c1c(N)n(CC(C)C)c(=O)[nH]c1=O +Nc1nc(SCc2nn(-c3ccc(F)cc3)c3c2CCC3)n[nH]1 +CCOCCCNC(=O)c1ccc(Cl)cc1O +CCC1(C)NC(=O)c2cc(Br)ccc2-n2nnnc21 +CCOCCC(=O)Nc1sc2c(c1C(=O)OC)CCCC2 +COCCOc1ccc(C(=O)Nc2cc(C)on2)cc1 +CCNC(=O)CN(CC)C(=O)Cc1csc(-c2cccs2)n1 +CC(O)CCNC(=O)CCc1ccc2ccccc2c1 +N#Cc1ccsc1NC(=O)c1ccc2c(c1)CCC2 +O=C1COc2cc(NC(=O)NCc3ccccc3)ccc2N1 +Cc1cccc(NC(=O)NCC(=O)N(C)CC2CCCC2)c1 +O=C(CSc1nncn1CC(F)(F)F)Nc1nccs1 +CCNC(=O)CCCC(=O)Nc1cc(F)ccc1OC +O=C(c1cccnc1)N1C2CCC(C2)C1COc1ccc(F)cc1 +Cc1ccc2oc(SCC(=O)Nc3nc(C)c(C)s3)nc2c1 +O=C(CCc1ccco1)Nc1ccc(Br)cc1F +CC(C)(C)c1ncc(NC(=O)NCCc2ccccn2)cn1 +CCn1c(C)nnc1COc1ccccc1C(=O)NC +CC(=O)N1CCN(C(=O)c2ccc(-c3ccsc3)nc2C)CC1 +CC(C)Nc1ncnc2c1cnn2-c1cccc(Cl)c1 +CC(C)C(=O)N1CCCC12CCCN(C(=O)c1ccno1)C2 +CN(c1cc(F)ccc1F)S(=O)(=O)c1ccc2[nH]c(=O)oc2c1 +N#CCCN(Cc1ccccn1)C(=O)Cc1ccc(C(F)(F)F)cc1 +Cc1nnc(NC(=O)CSc2ccc(-c3ccco3)nn2)s1 +CN(Cc1cccc(Cl)c1)C(=O)c1cccc(OCC(F)F)n1 +Cc1cc(-c2nnc(NC(=O)Cc3ccc4ccccc4c3)o2)n(C)n1 +O=c1[nH]c(Nc2nc3ccccc3o2)nc2c1CCCC2 +CCn1c(CN(C)C(=O)CCC(=O)c2ccccc2)nc2ccccc21 +COc1cccc(N2CCC(CNC(=O)NC(C)C(C)C)C2)c1 +O=C(Cc1cccc2ccccc12)Nc1ccccc1Cn1cncn1 +CC(C)CN(CC(C)C)C(=O)COc1cccc(C#N)c1 +CC(=O)NCC1CCN(c2cc(N)nc(N3CCOCC3)n2)CC1 +CC(C)(NC(=O)NCCCn1cccn1)c1cccc(F)c1 +COc1ccc(-c2n[nH]c(NC(=O)CCCc3cccs3)n2)cc1 +CCc1ccccc1NC(=O)c1cn2c(n1)CCCC2 +CCCc1nnc2sc(Cc3cc(OC)c(OC)c(OC)c3)nn12 +O=C(N1CCC(Oc2cnccn2)CC1)C12CC3CC(CC(C3)C1)C2 +CCOC(=O)c1c(NC(=O)Cc2cccs2)sc(C)c1C +O=C(Nc1nccs1)c1cc(O)c(OCc2ccccc2)cn1 +Cc1nn(-c2nc3ccccc3[nH]2)c2c1C(c1ccncc1)CC(=O)N2 +CNC(=O)c1cccc(-c2nc(-c3ccc(C#N)cn3)no2)c1 +O=C(NCC1CCCO1)N1CCOCC1C1CC1 +CC(=O)NCCNC(=O)NCC(c1cccc(C)c1)N1CCOCC1 +Cc1snc2sc(C(=O)NCCc3ccncc3)cc12 +CC(C)Oc1ccc(C(C#N)NCC(F)(F)F)cc1 +O=C(Nc1ccc(CN2CCOC2=O)cc1)C1CCCC1 +Cc1ccccc1OCC(=O)Nc1ncccc1OCc1cccnc1 +CC(C)NC(=O)COc1ccc2c(c1)OC1(CCCCC1)CC2=O +NC(=O)CCCNC(=O)c1cc2cc(Br)ccc2o1 +CN(CCCc1ccccc1)C(=O)c1scnc1C1CC1 +NC(=O)NCc1ccc(C(=O)NC2CCc3ccc(F)cc32)cc1 +Cn1cccc(C(=O)NCC#CCOc2ccc3cccnc3c2)c1=O +CC(Cn1cccn1)NC(=O)CCC(=O)c1cccs1 +N#Cc1ccc(CNc2ccc(Cl)cc2C(=O)N2CCCC2)cc1 +CN(Cc1cccc(C#N)c1)C(=O)Cn1ccc(C(F)(F)F)n1 +CCc1ccc(C(C)(C)C(=O)NCc2ncn(C)n2)cc1 +c1ccc2[nH]c(C3CCC(CNc4nnc(C5CC5)o4)CC3)nc2c1 +O=C(CSc1ncc2ccccn12)Nc1c(F)cccc1F +Cn1ncc2c(N3CCN(C(=O)OC(C)(C)C)CC3)ncnc21 +CNc1nc2c(c(=O)[nH]c(=O)n2C)n1CCC(C)C +O=C(Nc1ccc(SC(F)F)cc1)c1ccco1 +CCN(CC1CC1)C(=O)C1CN(Cc2ccccc2)CCO1 +O=C1CCN(C(=O)C2COc3ccc(F)cc3C2)CCN1 +Cc1nnc(-c2ccccc2NC(=O)NC(C)c2cn(C)nc2C)o1 +Cc1n[nH]cc1NC(=O)c1cnc2sccn2c1=O +Cc1nnc(-c2cccc(NC(=O)c3c[nH]nc3-c3ccccc3)c2)o1 +CCNC(=O)CNC(=O)NC(c1ccccc1F)C1CCCC1 +N#CCc1c(-c2cccnc2)nc2scc(-c3ccccn3)n12 +CC(NS(=O)(=O)c1ccc(Cl)cc1)C(=O)N1CCC(O)CC1 +N#CCc1ccc(NC(=O)NCC(O)COc2ccc(F)cc2)cc1 +CNS(=O)(=O)c1ccc(NC(=O)C2C3CC4CC(C3)CC2C4)cc1 +CN(C(=O)COc1ccc(C#N)cc1)C1CCCCC1 +COc1ccc(N)c(C(=O)NC2CCCCCC2)c1 +N#CC(C(=O)c1cc(C(N)=O)cs1)c1nc2ccccc2[nH]1 +COc1cccc(C=Cc2nc3ccccc3c(=O)[nH]2)c1OC +Cn1cnc(CNC(=O)NC2(c3ccc(Cl)cc3)CCCC2)n1 +O=C(NCCc1ccc2c(c1)OCO2)c1cc(C2CC2)[nH]n1 +O=c1[nH]nc(Cc2ccncc2)n1-c1ccccc1-c1ccccc1 +Cc1nc(CN2CCN(C(=O)c3ccc4c(c3)OCCO4)CC2)no1 +CC(C)C(CCO)NS(=O)(=O)c1ccc(F)c(C#N)c1 +CCCc1[nH]nc(C(=O)NC2(CO)CCCC2)c1N +COC(=O)C(C)CN(C(=O)c1ccc(-n2ccnn2)cc1)C1CC1 +CSc1ccc(C)c(C(=O)NC(CO)C(C)C)c1 +CNC(=O)c1cnc(COc2ccccc2C(C)C)nc1N +CCc1nc2ccccc2n1CC(O)c1ccc(F)cc1F +CN1CCN(C(=O)c2ccc3c(c2)CCO3)CC12CCNC(=O)CC2 +COc1ccc(-c2ccc(S(=O)(=O)N3CCCC3)cc2)cc1O +NC(=O)c1cc2ccc(OC(=O)c3ccco3)cc2oc1=O +CC1CCN(C(=O)c2cccc(-n3nnc4cccnc43)c2)CC1 +CC1(C)CC(=O)c2sc(NC(=O)c3c[nH]c4ccccc34)nc2C1 +CSc1ccc(C)c(C(=O)Nc2nccn(C)c2=O)c1 +O=C(NCC(=O)N1CCC(O)C1)c1cccs1 +O=C(NCCNc1cccc(F)n1)c1cccnc1 +Cc1cc(N)ccc1NC(=O)COC1CCCCC1C +CC(C)C(=O)NCCNC(=O)Nc1ccc(F)c(C(N)=O)c1 +N#Cc1c(NC(=O)c2cccnc2)sc2c1CCC2 +CCc1cnc(CNC(=O)c2ccnc(OC3CCC3)c2)s1 +Cc1cnc(-c2cccc(NC(=O)N3CCOC(C(N)=O)C3)c2)o1 +CCCc1nc(C(=O)N(C)Cc2nncn2C(C)C)cs1 +COc1ccc(NC(=O)c2ccc(CNC(C)=O)cc2)cn1 +O=C(NC1CC1)c1ccc(NC(=O)c2cc[nH]n2)cc1 +CCN(C(=O)c1sccc1C#N)c1ccccc1S(=O)(=O)CC +N#CCC(=O)NCc1cccc(OCc2ccccc2F)c1 +CS(=O)c1ccc(CNc2ccc(F)cc2OCC2CC2)cc1 +O=C(c1cccs1)N1CCN(Cc2c[nH]c3ccccc23)CC1 +CN(C(=O)c1cc2cccnn2n1)c1ccccc1 +CC(=O)c1cccc(-c2ccc3nc[nH]c(=O)c3c2)c1 +CC(C)(CNC(=O)c1cc2c(s1)CCC2)c1ccncc1 +CC1CN(Cc2ccc(CO)o2)CC(c2ccc(F)cc2)O1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NC(C)c1nncn1C +CN(CC(=O)NCCc1ccccc1)c1ccccc1 +CCOC(=O)c1cccc(NC(=O)N2CCCC2)c1 +COC(=O)C1CCN(C(=O)c2ccccc2-c2ccccc2)CC1 +CC(Nc1cccnc1)c1nc2ccccc2s1 +Cn1ccnc1CNS(=O)(=O)c1ccc2c(c1)oc(=O)n2C +CC1(C)CCC(NC(=O)Cc2ccccc2O)c2ccccc21 +CCOC(=O)c1nnc(C(=O)Nc2ccc(C)cc2)s1 +COCCc1ccc(OC(=O)c2cn(-c3ccccc3)nn2)cc1 +CCOC(=O)C(C)Nc1ccc(C)c(C(N)=O)c1 +CN(C(=O)COCCc1ccccc1)c1cccc(C#N)c1 +COCCn1c(-c2cnn(C(C)C)c2)nc2ccccc21 +CN(Cc1ccc(Cl)cc1)C(=O)NCc1cscn1 +CCn1cnc2cc(CNC(=O)c3ccsc3)ccc21 +CCCCOc1ccc(C(=O)N(C)C2(C#N)CCC2)cc1OC +O=C(NCCNS(=O)(=O)c1c(F)cccc1F)C1CC1 +Cc1c(N(C)C(=O)c2ccco2)c(=O)n(-c2ccccc2)n1C +Cc1ccc(CN(C)C(=O)Cc2ccc(F)c(F)c2)o1 +CC(C)=CC(=O)OCC(=O)NC1CCCc2ccccc21 +CCOc1c(C)cc(S(=O)(=O)NCC2(O)CCOCC2)cc1C +COc1ccc(CCCNC(=O)c2nc3ccccc3c(=O)[nH]2)cc1 +COC(=O)C=C(C)c1cccc(-c2cccnc2)c1 +CCS(=O)(=O)c1cccc(-c2cnn(C)c2)c1 +CCOC(C)c1nc(COc2cc(Cl)ccc2C(N)=O)cs1 +CCc1ccc(CCC(=O)Nc2ccccc2C(N)=O)cc1 +COCCC1(CNC(=O)NC2CC3(CCC3)Oc3ccccc32)CC1 +CCc1nc(C)c(C(C)N(C)C(=O)c2scnc2C2CC2)s1 +CCOCCS(=O)(=O)NC1(C)Cc2ccccc2C1 +Cc1nc(CC(=O)N2CC3CCC(C2)N(CC2CCC2)C3=O)cs1 +Clc1ccccc1NCc1nnnn1-c1ccccc1 +Cc1cc(C(=O)NCc2ccccc2OCC(F)(F)F)no1 +O=S(=O)(NCC#CCOc1cccnc1)C1CCCCC1 +CN(Cc1cccs1)C(=O)c1cc(N)cn1C1CC1 +CC1CN(Cc2nc3cc(F)ccc3n(C)c2=O)CC(C)O1 +COCCN(C)C(=O)c1cc2cc(Cl)ccc2[nH]1 +Cc1nc2ccc(C(=O)NCC(C)N(C)c3ccccc3)cc2nc1C +NC(=O)Cn1c(COc2cccc3ccccc23)nc2ccccc21 +CN1C(=O)CC(C(=O)NCC2(C)CCCC2)C1c1cccnc1 +CS(=O)(=O)c1ccccc1Cc1nccn1Cc1ccccc1N +CC(=O)N1CCC(C(=O)Nc2cc(-n3cccc3)ccc2F)CC1 +O=C(c1ccc(S(=O)(=O)N2CCCC2)cc1)N1CCCC1 +COc1cc(CO)c(OCc2noc(C3CC3)n2)c(CO)c1 +Cc1cc(F)ccc1NC(=O)C1CCCN1C(=O)c1ccccc1 +CN(Cc1cc(-c2ccccc2)no1)C(=O)c1ccc2ncccc2c1 +CN(CC1CC1)S(=O)(=O)c1ccc2c(c1)CCO2 +CN(CC1CC1)C(=O)c1cc(Br)c2c(c1)OCCO2 +Cn1c(SCCC(=O)Nc2ccccc2)nnc1N1CCOCC1 +COC(=O)c1cc(-c2ccccc2)nc2cc(C)nn12 +CC(=O)c1csc(NC(=O)Cc2cccc(C(F)(F)F)c2)n1 +O=C(c1ccccc1)N1CCN(C(=O)c2cn3cccnc3n2)CC1 +CCOC(=O)c1cc(N)n(-c2nccn2-c2ccccc2)n1 +Cc1[nH]ccc1C(=O)Nc1ccn(-c2ncccc2Cl)n1 +COc1ccc(C(=O)C2CCCN2S(C)(=O)=O)c(OC)c1 +c1cc(CN2CCCC(c3nnc4n3CCC4)C2)c2[nH]ncc2c1 +Cc1ncsc1CCC(=O)NCc1ccc2c(c1)n(C)c(=O)n2C +CC(C)c1nc(C2CCCN2Cc2nnnn2C2CC2)no1 +CNC(=O)C1CCC(NC(=O)c2ccco2)CC1 +Cc1noc(COC(=O)c2cc(Cl)ccc2O)n1 +O=C(C1CCC1)N1CCN(Cc2nc(-c3cccs3)no2)CC1 +Cn1c(=O)c2cc(C(=O)Nc3ccccc3C#N)sc2n(C)c1=O +CCCC(C)(NC(=O)c1ccc(-n2ccnc2)cc1)C(=O)OC +O=S(=O)(NCCNc1cnccn1)c1cccs1 +Cc1cc(C(F)(F)F)cc(=O)n1Cc1noc(C2CCCC2)n1 +Cc1cc(C(O)CCC(=O)N2CCCCC2)ccc1F +Cc1cccc(NS(=O)(=O)c2cccc(C(=O)NC(C)C)c2)c1 +Cn1c(=O)sc2cc(NC(=O)COc3ccc(Cl)cc3)ccc21 +Cc1nn(C)c(C)c1C1CCCN1C(=O)COC1CCCCC1 +N#CC(C(=O)c1cnn(-c2ccccc2)n1)c1nnc2n1CCCCC2 +CCc1cc2c(N3CCCC(C(=O)NC(C)C)C3)ncnc2s1 +COc1ccnc(NC(=O)Cc2csc(Cc3ccccc3)n2)c1 +CCCCn1nnnc1NCc1ccc2c(c1)OCO2 +CC1=CCC2CN(C(=O)CCn3ccccc3=O)CC2C1 +CC1CCCCC1NC(=O)NCC(O)c1ccccc1Cl +Cc1sc(C(N)=O)cc1S(=O)(=O)N=c1[nH]cc(C(C)C)s1 +CCCCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1cccs1 +O=C(c1cc2ccccc2[nH]1)N1CCn2c1nc1ccccc12 +CNC(=O)Nc1cc(C(=O)N2CCCC2)ccc1OC +CNC(=O)NCC(=O)Nc1cccc(C(=O)Nc2ccccc2)c1C +CCCc1n[nH]c(C2CN(C(=O)C(C)Oc3cccnc3)CCO2)n1 +CC(=O)NC(C)C(=O)OCC(=O)N(C)C1CCCc2ccccc21 +CC(NC(=O)N1CCOC(c2cccc(F)c2)C1)c1cccnc1 +CCCNC(=O)Cc1c(C)nc(SCc2ccc(F)cc2)[nH]c1=O +Nc1nc2scc(-c3c[nH]c4ccccc34)n2n1 +CNc1ccc(C(=O)NCc2cccc(Br)c2)cn1 +COC(=O)C(C)OC(=O)c1cccnc1Oc1ccccc1 +CCN1C(=O)CCCC12CCCN(C(=O)Cc1ccc(OC)cc1)C2 +CN(Cc1ccccn1)C(=O)Nc1ccccc1OCCC(N)=O +COCCOCC1NCCc2ccc(C(F)(F)F)cc21 +CC(C)Nc1cccc(CNC(=O)c2cc(-c3ccco3)[nH]n2)c1 +CN(CC(F)(F)F)C(=O)CSc1nc2ccccc2[nH]1 +CN(C(=O)c1nc(-c2ccncc2)no1)c1ccccc1Cl +CN(C)C(=O)Cc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1 +COC(=O)C(NC(=O)Cn1ncc2ccccc2c1=O)C(C)C +CC(=O)NC(C(=O)N=c1sccn1C)C(C)C +Cc1noc(C)c1C(C)C(=O)N1CCCN(C)c2ccc(Cl)cc21 +CNC(=O)c1ccc(CNc2cc(C)ccc2-n2cc(C)cn2)cc1 +COc1cc(=O)n(-c2ccccc2)nc1C(=O)Nc1cc(C)ccc1C +CC1CCN(C(=O)C2CCCN2C(=O)Cc2cccs2)CC1 +COc1ccnc(C(=O)N2CCCCCC2c2ccco2)c1 +COc1ccc(C(=O)OCC(=O)Nc2cc(F)cc(F)c2)cc1 +COC(=O)C(C)(C)NCc1nc(-c2cccc(Cl)c2)no1 +O=C(Nc1ccc(CN2CCOCC2)c(Cl)c1)c1cc[nH]n1 +Cc1cnc(C(=O)Nc2ccccc2S(=O)(=O)NC(C)(C)C)cn1 +CNC(=O)c1ccc(NCc2nc(CCC(C)C)no2)cc1Cl +CCC(=O)N1CCN(C(=O)NCc2c(CC)noc2CC)CC1 +O=C(COC(=O)c1ccccn1)Nc1ccc(C(F)(F)F)cc1 +CC(C)NC(=O)NC(C)c1cccc(OC(F)F)c1 +Cc1cc(-c2ccc(S(=O)(=O)Nc3ccccc3F)s2)[nH]n1 +CCCCS(=O)(=O)N(C)CCc1ccccn1 +Nc1ccc(-c2csc(-c3cnccn3)n2)cc1 +O=C(NCc1noc(-c2ccco2)n1)c1cc2c([nH]c1=O)CCC2 +COCc1cccc(NC(=O)CCc2nc(C(C)(C)C)no2)c1 +CCOC(=O)c1nnc(C=Cc2ccc(Br)cc2)s1 +COC(=O)CCN(C)C(=O)c1cccc2[nH]ccc12 +Cc1cc(C(=O)NC2CCCc3[nH]c(=O)ccc32)[nH]n1 +Cc1ccccc1SCC(=O)OCC(=O)N1CCCC1 +Cc1nc2cc(C(=O)Nc3cccc(Cl)c3)ccc2[nH]1 +O=C(Cc1ccccn1)N1CCC(O)C1Cc1ccccc1 +CCc1noc(CCCC(=O)NC2CCCNC2=O)n1 +Cc1nc(CCNC(=O)CSc2ccccc2C)cs1 +CC(O)c1nc2ccccc2n1CC(=O)N1CCOCC1 +Cc1cnc(CNS(=O)(=O)c2ccc(Br)cc2F)o1 +CC(c1n[nH]c(=O)n1Cc1ccccc1)n1ccnc1 +CSc1ccc(CNC(=O)c2ccccc2Cn2cncn2)cc1 +CNS(=O)(=O)c1cc(NC(=O)NCc2ccncc2)ccc1C +CCn1c(SC2CCOC2=O)nnc1-c1ccccc1OC +COCCN(Cc1cnn(C)c1)C(=O)c1cnc(N(C)C)nc1C +COCCC(=O)N1CCCc2cc(Br)cc(C)c21 +Cc1nc(CNC(=O)Cc2nc(-c3ccccc3)oc2C)c(C)s1 +COc1ccc(C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)cc1 +COc1c(C)cnc(CNC(=O)Nc2ccc(F)c(C(N)=O)c2)c1C +Cc1noc(-c2ccc(C(=O)Nc3cccc4ncccc34)cc2)n1 +CN(C)S(=O)(=O)c1ccc(CNC(=O)c2ccoc2)s1 +CC(=O)N1CCN(C(=O)COCc2nc3ccccc3s2)CC1 +CC(C)(C)c1nnc(SCC(=O)Nc2ccc(F)c(F)c2)n1N +Cc1c(F)cccc1NS(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +O=C(Cn1ccccc1=O)N1CCCC1c1cccs1 +O=C1CCCC2C3CC(CN(c4nnnn4-c4ccccc4)C3)CN12 +Cc1cc(C(=O)N2CCN(Cc3ccc(F)c(C)c3)CC2)c(C)o1 +COc1cccc(C(=O)Nn2c(C)nnc2-n2nc(C)cc2C)c1 +CC(C)Oc1ncc(C(=O)N2CCN(CC(N)=O)CC2)cc1Cl +Cc1ccc(NC(=O)c2cc(-c3ccncc3)[nH]n2)cc1N(C)C +C=CCNC(=O)C1CCCN1C(=O)Nc1ccccc1 +CCOc1ccc(NC(=O)C(C)Sc2nc(N)cc(=O)[nH]2)cc1 +CN(C)C(=O)C1CN(Cc2ccon2)CCN1Cc1ccon1 +CC(C)COc1ncccc1C(=O)NCC(N)=O +Cc1nn(C)c(C)c1C(=O)NCCNc1ccc(C(F)(F)F)cn1 +CCN(C)C(=O)c1cc(S(=O)(=O)NC(C)(C)C)ccc1C +CCCCNc1ncnc(N2CCC(C)CC2)c1N +CCOc1ccc(NC(=O)c2cccc(F)c2)cc1CO +O=C(Nc1ccc2c(c1)OCCCO2)c1ccc(-n2cccn2)cc1 +O=C(C1CCOCC1)N1CCc2sccc2C1c1ccccc1 +COCCOc1ncccc1C(=O)N1CCC(C(N)=O)CC1 +COC(=O)C1CN(C(=O)c2ccc(OC)cc2)CCN1C(C)=O +CNC(=O)CN1CCN(C(=O)C(C)(C)Cc2ccccc2OC)CC1 +CC(NC(=O)NCC1CCCO1)c1ccc2c(c1)OCCCO2 +Fc1ccccc1SCCCc1nc(-c2ccncc2)no1 +O=C(c1cscn1)N1CCOC2C(Oc3cccnc3)CCC21 +O=C(NCCO)C1(S(=O)(=O)c2ccc(Cl)cc2)CCCC1 +Cc1ccc(C(=O)N2CCOC(C)(C)C2)c(O)c1C +Cc1ccc(NS(=O)(=O)c2c(N)n(C)c(=O)n(C)c2=O)cc1C +Cc1c(O)cccc1C(=O)NCc1nnc(C2CC2)n1C1CC1 +CC(=O)c1ccccc1NC(=O)COC(=O)c1c(C)noc1C +Cc1nn(CCc2ccc3c(c2)OCCCO3)c(C)c1N +Cc1[nH]c(C(=O)N2CCC(CC(=O)N3CCCCC3)CC2)c(C)c1C +CCc1nn2c(=O)cc(CNc3ccccc3F)nc2s1 +CC(=CC(=O)OCc1nc(C)no1)c1ccccc1 +CCOCCNC(=O)N(C)C(C)c1ccccc1F +CC(=O)N1CCC(c2nc(O)cc(-c3nccs3)n2)CC1 +CS(=O)(=O)N1CCCC(C(=O)NCc2cn[nH]c2)C1 +CC1CCC(NC(=O)NC(C)C(=O)N2CCCCC2C)CC1 +O=C(c1[nH]nc2c1CCCC2)N1CCc2ccccc2C1 +CCCC(=O)NCC(=O)Nc1ccc(C)cc1OC +CC(C)(C)c1cc(CN2CCN(c3ccnc4nncn34)CC2)n[nH]1 +Cc1ccc(NC(=O)c2[nH]nc(C(C)C)c2Br)nc1 +NC(=O)CN(C(=O)c1ccc(F)cc1F)C1CCCC1 +N#Cc1nnn(Cc2ccccc2)c1C1CCCO1 +O=C(COc1ccc2ccccc2c1CO)N1CCCCC1 +O=C(Cc1ccccc1F)NCCNC(=O)c1cnn2c1SCC2 +COC(=O)C1=C(C)Nc2ncnn2C1c1ccncc1 +CC(=Cc1ccccc1)C1CC(=O)Nc2n[nH]cc21 +COc1ccc(-c2cc(C#N)nn2CC(N)=O)c(C)c1 +Brc1ccccc1C1CN(Cc2ccon2)CCO1 +Cn1cc(CN2CC3OCC(C(=O)NCc4cccnc4)C3C2)cn1 +O=C(NC(c1ccccc1)C1CC1)c1cnn(-c2ccccc2)n1 +CCn1cnc2ccc(C(=O)N3CCCC3)cc2c1=O +Cc1ccc(-c2nnc(C)c(N3CCCC3)n2)cc1 +Cn1nnnc1SCCOc1ccc(Br)cc1 +CNS(=O)(=O)c1cccc(C(=O)N2CCCCC2)c1 +Cc1cc(=O)c(C#N)nn1-c1ccc(Cl)c(Cl)c1 +CC(C)NC(=O)c1cc(S(=O)(=O)N2CCCC2)cn1C +NC(=O)c1ccc(CNC(=O)Nc2ccncc2)cc1 +CCc1cc(=O)n(CC(=O)Nc2cccc(F)c2)c(N)n1 +CCc1ccc(C(=O)N2CCN(Cc3noc(C)n3)CC2)cc1 +CCNC(=O)C1CCN(S(=O)(=O)c2ccc(CC)s2)CC1 +COCCNC(=O)c1cc(NC(=O)C2CC2)n(-c2ccccc2)n1 +CC(NC(=O)NC1CCCc2occc21)c1ccccc1Cl +Cn1nc(-c2ccc(F)cc2)cc1C(=O)NCc1ccco1 +COc1ccnc(NC(=O)C(C)Oc2ccc(Cl)cc2)c1 +CC1CC1Nc1ccccc1S(=O)(=O)C(F)F +O=C(CCc1cc(Cl)cs1)NCC(O)c1c(F)cccc1F +COC(OC)(OC)c1cc(Cl)c(=O)n(Cc2ccccc2)c1 +COC1CC(OC(=O)C2CC2c2cc(F)ccc2F)C1 +CCCCC(=O)c1ccc(S(=O)(=O)CCC)cc1 +CNC(=O)c1cccc(C2CCCN2S(=O)(=O)c2cn(C)cn2)n1 +O=C(CCc1ccccc1)Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3 +NC(=O)c1[nH]nc2c1CCOc1c(Cl)cc(Cl)cc1-2 +CC(CO)NC(=O)Cc1c(Cl)cccc1Cl +CC(C)(CS(=O)(=O)N1CCNCC1)C(=O)NC1CCCC1 +N#Cc1ccsc1C(=O)Nc1cnn(-c2ccccc2F)c1 +O=C(c1ccccc1O)N1CCN(CC(F)(F)C(F)F)CC1 +CC(C)Oc1ccccc1CNS(=O)(=O)c1cn[nH]c1 +N#Cc1ccccc1OCC(=O)N=c1[nH]nc2ccccn12 +CC(OC(=O)CC1Sc2ccccc2NC1=O)C(=O)NC1CC1 +O=C(NCc1ccccc1Cl)Nc1ccc(N2CCOC2=O)cc1 +NC(=O)c1ccc(C(F)(F)F)n(Cc2cccc(F)c2)c1=O +CCOC(=O)c1nnn(-c2ccc(C)c(C)c2)c1C(=O)OCC +Nc1c(Oc2ccc3ccccc3c2)ncnc1N1CCOCC1 +COc1ccc(OC)c(NC(=O)CCNc2cnc3cnccn23)c1 +CCNC(=O)C(C)NS(=O)(=O)c1cccc(-n2cnnn2)c1 +CC(=O)Nc1ccc2c(c1)nc1n2CCN(C(C)C)C1 +CC(=O)NC1Cc2ccccc2C1NC(=O)c1c[nH]nn1 +O=C(c1ccc[nH]c1=O)N1CCC(OC2CCCC2)CC1 +CN(C(=O)CSc1nc(-c2ccccc2)n[nH]1)c1ccccc1 +CC1CCN(C(=O)C(C#N)Cc2ccccc2F)CC1 +Cc1cccc(C(=O)NCC2CN3CCCCC3CO2)c1C +CC1CC1CNC(=O)NCC(=O)Nc1ccccc1Br +CC(C)(C)OC(=O)N1CCCC(C(=O)NC2CC2)C1 +COc1ccc(C2NC(=O)c3cccnc3N2)cc1 +CC(=O)c1ccccc1C(=O)NC1CCCC(C(=O)NC(C)C)C1 +Cc1occc1C(=O)NCc1ccc(S(=O)(=O)NC2CC2)cc1 +Cn1cnnc1-c1cccc(NS(=O)(=O)c2cccs2)c1 +O=C(NC1CCc2c1ccc(Cl)c2Cl)C1COCCO1 +COCCOc1ccccc1NC(=O)CN1CCCCC1=O +NC(=O)COc1ccc(S(=O)(=O)N2CCC(CO)C(O)C2)cc1 +C#CCn1c(=NC(=O)c2cnccn2)sc2cc(F)cc(F)c21 +COc1cccc(OCC(=O)NCc2cn3cc(Cl)ccc3n2)c1 +CCSc1ccc(Cc2nnc(NC(=O)c3ccnn3C)o2)cc1 +CC(C)c1nnc(Sc2ccc3nnc(C(F)(F)F)n3n2)n1C +COCCSc1ncc(-c2ccc(Br)cc2)[nH]1 +COc1ccccc1NC(=O)c1cn(C)c2c(Cl)cccc2c1=O +COCC(O)CN(C)C(=O)CN1CCOc2ccc(Cl)cc21 +Cc1snc(-c2cccc(Br)c2)c1C#N +Cc1ncsc1COC(=O)c1cnn(Cc2ccccc2)c1 +CCCNC(=O)NCc1cccc(NC(=O)C(C)CC)c1 +COc1cccc(C(C)N2CCN(C(=O)Cc3cc(C)on3)CC2)c1 +COC(=O)c1cc(-c2csc(NC(=O)C(C)OC)n2)c[nH]1 +CN(C(=O)c1cccc(S(=O)(=O)N2CCCC2)c1)C1(C#N)CCC1 +N#Cc1ccc(OCC(O)Cn2cnc3cc(F)c(F)cc32)cc1 +Cc1[nH]ccc(=O)c1OCC(=O)N1CCN(c2ccc(F)cc2)CC1 +COc1cccc(NC(=O)NCC(C)(O)c2ccco2)c1OC +NC(=O)c1cccc(OC(=O)CCn2ccc3ccccc32)c1 +CN(CC(=O)NC(c1ccc(F)cc1)C1CCCO1)c1cnccn1 +CCN1CCN(C(=O)CCc2cc3ccc(C)cc3[nH]c2=O)CC1 +CC(Sc1nnc2ccc(C(F)(F)F)cn12)C(=O)N(C)C +Cc1cc(Cl)ccc1NC(=O)NCC(=O)NC1CC1 +CC(OC(=O)c1ccc2c(c1)OCCCO2)C(=O)NC(C)(C)C +CCc1nc(CNc2ccc(C(=O)NC(C)C)cc2)no1 +CNc1cc(NS(=O)(=O)c2ccccc2)ccc1OC +Cc1cccc(C(CNC(=O)NCCCO)N2CCOCC2)c1 +Cc1cc(C(=O)N(C)CCOCC2CC2)c(C)n1C(C)C +CCOC(=O)c1ccccc1NC(=O)C1Cc2ccccc2C(=O)O1 +CCc1nc2cc3c(cc2n1Cc1ccc(C#N)cc1)OCCO3 +Cc1nnc(SCC(=O)NC2CC2)n1-c1ccccc1 +CCc1ccc(CN(C)C(=O)c2cc(CC(C)C)nn2CC)nc1 +O=C(Cn1ncc2c1-c1ccccc1OC2)NCc1ccccc1 +O=C(NCc1ccoc1)NC1CCN(c2ncccn2)CC1 +COc1ccc(O)c(C(=O)N(C)Cc2ccc(Cl)cc2)c1 +CCCCC(=O)Nc1cc(NC(C)=O)ccc1OC +Cc1cc(NC(=O)c2nnn(-c3ccc(Cl)cc3)c2C)no1 +CCC(C)Sc1nnc2n(CCCOC)c(=O)c3ccccc3n12 +CCN(CC)C(=O)C1CC=CCC1C(=O)Nc1cccnc1 +COc1cc(C2NCCc3cc(O)c(OC)cc32)ccn1 +Cc1cccc(OCCCCn2nnc(C#N)c2C)c1 +O=C(Nc1ccc(N2CCCC2)nc1)c1ccc2c(c1)OCO2 +NC(=O)C1CCN(C(=O)Cc2ccc(-n3cccc3)cc2)CC1 +Cc1nnc2sc(CCc3cccc(N)c3)nn12 +CCN(C(=O)c1cccc(OCC(F)F)n1)c1ccccc1 +COC(C)(C)c1noc(-c2[nH]c(C)c(C(=O)OC(C)C)c2C)n1 +Cc1ccc(-c2ccc(C(=O)NCCCc3ccco3)c(=O)[nH]2)cc1 +O=C1c2ccccc2S(=O)(=O)N1CCc1nnc2n1CCCCC2 +Cc1cc2occ(Cc3nc(C4CCOC4)no3)c2cc1Cl +COc1ccc(Cl)cc1CNC(=O)Nc1nccs1 +O=C(NC1CC1)c1sc2cc(F)ccc2c1Cl +CCSc1ccc(C(=O)N(C)C2(C(=O)OC)CCCCC2)cn1 +C=CCNC(=O)c1ccc2c(c1)N(Cc1ccccc1)C(=O)CO2 +O=C(Cn1nnc(-c2ccsc2)n1)N1CCCc2ccccc21 +CCCC(=O)Nc1ccc(C(=O)Nc2cccc(OC)c2)cc1 +CC(=O)c1sc(NC(=O)C2CC3CCC2C3)nc1C +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)Nc1ncccc1C)O2 +O=C(Cn1cnc2cc(F)c(F)cc21)NCCc1ccccc1 +CC(OCC1CC1)C(=O)NC1CCCN(c2ccccc2)C1=O +Cc1ccc2nc(-n3nc(C)c(C(N)=O)c3C)sc2c1 +Cc1ccc(CC(=O)NCc2ccc(-n3ccnc3C)nc2)s1 +COc1ccc(S(N)(=O)=O)cc1C(=O)NC1CCCCC1 +O=C(NCc1cc(F)ccc1F)N1CCN(Cc2ccccc2)CC1 +COCC(=O)NCCS(=O)(=O)c1ccc(Cl)cc1 +CNc1snc(C)c1C(=O)NCCOc1cccc(C)c1 +CCc1onc(C)c1NC(=O)N1CCCC1c1cccc(N(C)C)c1 +CCOC(=O)n1nc(N)c2cc(C(F)(F)F)cc(N)c21 +Cc1cccc(NC(=O)c2ccc3c(c2)NC(=O)C2CCCN32)c1 +O=C1CN=C(c2ccccn2)c2cc(Cl)ccc2N1 +Cn1ccnc1SCCC(=O)NCC1CCCO1 +CCCCNC(=O)C1CCCN(C2=NS(=O)(=O)c3ccccc32)C1 +Cc1ccc(CN2CCN(CC(=O)c3cccs3)CC2)cc1 +O=C1CC2CCC(CN1)N2C(=O)c1cnc(-c2ccncc2)nc1 +CCC(=O)Cn1c(-c2ccccc2)c(C)sc1=O +COc1cccc(N2CCN(C(=O)C3(c4ccccc4)CC3)CC2)c1 +Cc1ccc(S(=O)(=O)NS(=O)(=O)c2ccccc2)cc1 +COc1ccc(-c2noc(CCCC(=O)N3CCCC(O)C3)n2)cc1 +CCC(C)NC(=O)c1ccc2c(c1)CCN2S(=O)(=O)CC +Cc1ccc(CN2CCCC(c3nnc(-c4cnccn4)o3)C2)cc1 +CC(C)c1cc(C(=O)N2CCC(O)(C3CCOCC3)C(C)C2)no1 +CCCNC(=O)C(C)N1CCN(S(=O)(=O)N2CCOCC2)CC1 +Cc1ccn(-c2ccccc2NCc2cnc(-c3cccnc3)s2)n1 +Cc1cc(C)c(S(=O)(=O)N2CCCC2C(=O)N2CCC2)c(C)c1 +O=C(CCCc1nc2ccccc2c(=O)[nH]1)Nc1ccccn1 +NC(=O)C(NC(=O)c1ccc(F)c(F)c1)c1ccccc1 +Cc1nc(CN2CCCC(c3noc(C4CC4)n3)C2)no1 +COCC(C)n1c(C)cc(C(=O)CN2CCOCC2C)c1C +CCc1cc(Cl)ccc1NC(=O)N(Cc1cnn(C)c1)C1CC1 +CSc1ccccc1NC(=O)C(C)Sc1nncs1 +CCOC(=O)C1CCCN(C(=O)NCc2ccc(OC)c(F)c2)C1 +Cc1cc(C(C)NC(=O)N2CCN(c3ccccc3)CC2)c(C)o1 +COC(=O)CCNC(=O)C(N)c1ccc(C)c(C)c1 +CCC(C)NC(=O)C(C)NC(=O)NC(C)c1ccc(Cl)cc1 +Cc1c(CN2CC(C)OCC2c2ccccc2)cc(C#N)n1C +CN(Cc1ncnn1C)C(=O)C1CC(=O)N(C)C1c1ccc(F)cc1 +N#CCOC(=O)c1cc(-c2cccs2)nc2ccccc12 +CCC(=O)Nc1nnc(CCCc2ccccc2)s1 +O=C(c1ccccc1)C1CCCN(C(=O)c2ccc3c(c2)CCC3)C1 +CC(=O)c1cccc(NC(=O)COc2ccc(C#N)cc2)c1 +c1cncc(-c2ccnc(NCCCn3cncn3)n2)c1 +O=C(c1ccncc1F)N1CCC(Oc2ccccc2Cl)CC1 +N#Cc1ccccc1OCC(=O)Nc1ccc(Cl)cc1F +COc1ccc(CNC(=O)NCc2ccccn2)cc1O +NC(=O)C1CCCC1NC(=O)NCC1CN2CCCCC2CO1 +Cc1nn(-c2ccccc2)c(C)c1NC(C)C(=O)NC(C)(C)C +O=C(CNC(=O)c1ccc2c(n1)NC(=O)CC2)NCc1ccco1 +O=C(CSc1nccc(N2CCOCC2)n1)OCc1ccccc1 +O=C(CC1(O)CCCCC1)NCc1cccnc1OCC(F)(F)F +CC(C)C(=O)c1ccc(SCC(=O)Nc2ccccn2)cc1 +CC(=O)c1cc(CC(=O)NCc2ccccc2F)cs1 +N#CCOc1cccc(CC(=O)Nc2ccc(C(N)=O)c(F)c2)c1 +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)CC(=O)N3)s1 +CN(C(=O)c1cc2ccccc2oc1=O)C1CCc2ccccc21 +CCOC(=O)COCCn1c(=O)sc2ccccc21 +CCCC1CN(C(=O)C2(O)Cc3ccccc3C2)CCO1 +CN(C)c1nc(N)nc(COC(=O)c2cc(Br)c[nH]2)n1 +COc1ccc(OC(C)C(=O)NC2CCC(=O)NC2)cc1 +Cc1cc(OC(=O)c2cc(C(N)=O)cn2C)cc(C(C)C)c1 +CC(C)n1nccc1NC(=O)CCCc1cccs1 +CCCCCCNC(=O)c1cnc(C2CCCO2)nc1N +Nc1cccc(CNS(=O)(=O)Cc2cccc(F)c2)c1 +CCc1nc(C)ncc1C(=O)N1CCCC(c2noc(C)n2)C1 +C=CCNC(=O)c1ccccc1NCc1ccc(F)c(F)c1 +CCNC(=O)CCc1nc2c(C)nn(-c3ccccc3)c2n(C)c1=O +COc1cc(C(C)=O)ccc1OC(=O)c1cc2ccccc2oc1=O +O=C(NCc1ccco1)c1cc(-c2ccncc2)nc2ccccc12 +CNS(=O)(=O)c1ccccc1NC(C)COC +COc1ccc(CNC(=O)COc2ccc(Cl)c(Cl)c2)cn1 +CNS(=O)(=O)c1ccc(C(=O)OCC#Cc2ccccc2)cc1 +CC1CCCC(NS(=O)(=O)c2ccccc2N)C1 +CCOCCCNC(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +CCN(CC(F)(F)F)C(C)C(=O)c1ccccc1 +CC(C)N(C(=O)C1CSc2ccccc21)C1CCOCC1 +CC(=O)c1nc(C)c(Cc2nc(C)c(C)o2)s1 +Cc1sc(NC(=O)c2cc(Cl)ccn2)c(C(N)=O)c1C +O=C(C1CCC1)N1CCC2(CC1)Nc1ccccc1-n1cccc12 +CCn1nc(C)c(-c2cc(-c3cccc(O)c3)c(C#N)c(N)n2)c1C +Cc1ccc(-c2noc(CN3CCOCC3C3CC3)n2)cc1F +O=C(NCCN1CC2CC1CO2)c1cc2ccccc2s1 +Cc1nc(NCCC2CC3CCC2C3)c2cnn(C)c2n1 +O=C(Nc1nn2cnnc2s1)c1ccc2c(c1)OCCO2 +O=S(=O)(Nc1cccn2ncnc12)c1ccccc1Cl +O=C(CNC(=O)c1cccc(Cl)c1)Nc1nc2ccccc2[nH]1 +CC1CC(C)CN(S(=O)(=O)CC23CCC(CC2=O)C3(C)C)C1 +Cc1nc(CNC(=O)CC2C(=O)NCCN2Cc2ccc(C)o2)n[nH]1 +Cc1cccc(N2CCN(C(=O)NCc3c(C)noc3C)CC2)c1C +CS(=O)(=O)c1ccc(OCC2CCCCC2)cc1 +CCCC1CN(C(=O)c2cc(-c3c(C)nn(C)c3C)n[nH]2)CCO1 +CCc1cnc(CNC(=O)NC2c3ccccc3CC2O)s1 +Cc1cc(C)c(NC(=O)CCc2cnn(C)c2)c(C)c1 +CCC(C)(C)NC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1 +Cc1cc(C)c(NC(=O)C2CC(=O)N(C3CCCCC3)C2)c(C)c1 +COc1ccc(CC(O)c2ccc(OC)c(OC)c2)cc1 +COc1ccc(CC(=O)NC2CC(=O)N(CC(C)(C)C)C2)c(OC)c1 +CN(CCO)C(=O)CC(c1ccccc1)c1ccccc1 +CCc1ccc2nc(CCn3cc(C)cn3)[nH]c(=O)c2c1 +CCCC(=O)Nc1ccc(CNS(=O)(=O)N(C)C)cc1 +Cn1nc(C(=O)Nc2nc(C3CCCO3)n[nH]2)c2ccccc21 +CCCC(=O)NCC(c1ccc(C)o1)N1CCOCC1 +COCC1CCCN(C(=O)Cc2ccc(SC(C)C)cc2)C1 +CC(C)N(Cc1ccccc1)C(=O)c1cnc2[nH]ccc2c1 +Cc1n[nH]c(C)c1S(=O)(=O)N(C)C(C#N)C(C)C +CCn1c(C2CCN(C(=O)c3ccc(Cl)cn3)CC2)nn(C)c1=O +CC(NCC1(c2ccccc2F)CC1)c1ccc(S(N)(=O)=O)cc1 +Clc1cccc(CNCc2ccncc2Cl)c1 +CCOC(=O)CC(C)c1cn(C)c(=O)n(C)c1=O +COc1cc(C(=O)Nc2cc(C)nn2C)ccc1C +N#Cc1ccc(NC(=O)CN2C(=O)CSc3ccccc32)cc1 +CCn1nc(C2CCCC2)nc1-c1cnc2ccnn2c1C +CNC(=O)c1cc(C)ccc1NC(=O)c1ccc(C(F)(F)F)nc1 +CC(C)(C)C(=O)NCC(=O)Oc1ccc(-n2cnnn2)cc1 +Cc1nc2ccc(NC(=O)NCc3ccoc3)cc2s1 +CCN(Cc1cccc(C(=O)NC)c1)Cc1cccs1 +CC#CC1NCCc2cc(Br)c(O)cc21 +CC(C)CCNC(=O)NC(C)c1nnc2ccccn12 +COc1ccc(CNC(=O)Nc2cnn(-c3ccccc3F)c2)cn1 +CC(C)N(C)C(=O)NCCCNC(=O)c1cccc(F)c1 +C#CCOc1cccc(NC(=O)C2(c3ccccc3)CCOCC2)c1 +Cn1c(SCc2nccn2C(F)F)n[nH]c1=O +Cc1ccccc1-c1nc(C)c(C(=O)N2CCCC2)s1 +CCn1nc(-c2ccc3c(c2)CCCC3)cc(CO)c1=O +Cn1c(CNc2ccccc2F)cc(=O)n(C)c1=O +C#CCNC(=O)NC1CCSc2ccc(F)cc21 +O=C1c2ccccc2S(=O)(=O)N1CCOc1ccc(F)cc1 +CC(C)CCNC(=O)C(C)Nc1cccc(N2CCOC2=O)c1 +CCc1ccc(C(N)C(F)(F)C(F)(F)F)cc1 +CC(NC(=O)c1ccccc1S(C)(=O)=O)c1ccccc1 +Cc1ccc(OCCn2c(C(C)C)ccc(C#N)c2=O)cc1 +CC(C)CNC(=O)CCC(=O)c1ccc2c(c1)CCC2 +Cc1ccc(NC(=O)NCC(=O)NCc2ccco2)cc1Cl +O=C(c1ccsc1)N1CCCN(C(=O)C2CC=CC2)CC1 +CC(=O)N1CCc2ccccc2C1CC(=O)Oc1cccc(Cl)c1 +Cc1ncsc1CN(C)CCc1ccc(F)cc1 +Cn1cnc(CNC(=O)NCCCc2ccc(Cl)cc2)n1 +CC(=O)c1c[nH]c(C(=O)Nc2cccc(-n3cnnc3)c2)c1 +CN(C)C(=O)N1CCN(C(=O)NC(c2ccccc2)C(C)(C)C)CC1 +Cc1n[nH]c(C)c1NS(=O)(=O)c1c[nH]nc1N +COc1ccc(C)cc1C1CCCn2nc(N)nc21 +Cc1cc(NC(=O)Nc2cccc(Cl)c2)n[nH]1 +CC(=O)Nc1ccc(NC(=O)c2cn3cc(Cl)ccc3n2)cc1 +COc1cccc(CCNS(=O)(=O)C2CC2)c1 +CCOCC(=O)OC(C)C(=O)Nc1cc(Cl)ccc1Cl +CN(CCO)C(=O)CCc1ccc(Br)cc1 +CCCN1C(=O)C2(OCCO2)c2cc(Br)ccc21 +CC(C)CC(NC(=O)C1CCCCC1)C(=O)NCc1ccccn1 +O=C(NCCc1cc(F)cc2c1OCOC2)c1ccc2nncn2c1 +CC(C)c1nncn1CCNC(=O)Cc1ccc(F)cc1F +CC(c1ccco1)N(C)C(=O)NC1CCN(S(C)(=O)=O)CC1 +O=c1c2oc3ccccc3c2ncn1CC1CCC1 +Cc1cc2nnc(SCc3ccc(F)cc3Cl)n2c(C)n1 +CC(=O)N(Cc1cc(=O)[nH]c2ccccc12)c1ccccc1 +Cc1cc(C(=O)NCC(=O)NCC2CCOC2)c(C)o1 +O=C(NCc1cccc(Cl)c1)c1cccc(-n2cnnn2)c1 +Cc1cc(N)c2onc(CC(=O)NC3CCCCC3C)c2c1 +Cc1nnsc1C(=O)Nc1cc(N2CCCC2)ncn1 +Cn1cc(-c2nnc3sc(-c4ccc(F)c(F)c4F)nn23)cn1 +CCOc1ccc(S(=O)(=O)N2CCCN(C(C)=O)CC2)cc1C +CC(C)Cc1noc(C2CCN(C(=O)CCc3ccccc3)CC2)n1 +O=C(NCc1ccco1)c1ccc(C#Cc2ccccc2)cc1 +N#CCOc1ccc(NC(=O)c2cn(Cc3ccccc3)nn2)cc1 +COCc1cccc(CNC(=O)Cn2cnc(C#N)n2)c1 +Cc1ccc(C)c2c1CCNC2c1cc(Cl)c[nH]c1=O +CCCCC(=O)NC(C)(C)c1ccc2c(c1)OCCO2 +COc1cccc(CNC(=O)c2n[nH]c3cc(Cl)ccc23)c1 +CC(C)N(Cc1ccccc1)c1ncnc2c1nnn2C +Cc1ccc(C(F)(F)F)cc1NCc1nnc(C(C)(C)C)o1 +CC(NC(=O)NC1CCCC1)c1ccc(F)cc1 +O=C(CCc1ccco1)Nc1cccc(-c2nnnn2C2CC2)c1 +Cc1ccc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)nc1 +COCCC(=O)N(C)Cc1nc(C)ncc1-c1ccncc1 +Cn1c(N2CCN(C(=O)c3cccs3)CC2)cc(=O)n(C)c1=O +CC(C)C(=O)Nc1ccc2c(C(C)C)cc(=O)[nH]c2c1 +Cc1ccc(Nc2nc(N)nc(CSc3nccn3C)n2)c(C)c1 +Cc1csc(NCc2ccc(O)cc2Cl)n1 +CC1(C)COC(=O)C1OC(=O)Cc1cccc2cccnc12 +NC(=O)C1CCCN1C(=O)Cc1cccc2ccccc12 +C=C(C)CN(CC)C(=O)C(C)Sc1ccccn1 +COCCN(CC(C)C)c1cc(Br)ccc1CO +Cc1noc(CNC(=O)Cc2cn(C)c3ccccc23)n1 +CC1(C)C(NC(=O)c2cccs2)C2CCOC21 +COC(=O)c1ccc(COc2ccc(N)cc2F)o1 +Cc1cc(C)n2nc(SCC(=O)c3ccc(F)c(F)c3)nc2n1 +N#Cc1ccc(NC(=O)Nc2cccc(F)c2)cc1 +CCC(O)CN1CCN(C(=O)Cc2n[nH]c(=O)c3ccccc23)CC1 +COC(=O)CC(C)NC(=O)c1ccc(OC(F)(F)F)cc1 +CC1CCCC(C#N)(NS(=O)(=O)CCC2CC2)C1 +Cc1ccc(C)c(C(=O)CSc2nnc(C)s2)c1 +CCN(Cc1cnn(C)c1)c1ccc(-c2nc(CC(C)C)no2)cn1 +COc1ccc(CCNC(=O)c2ccccc2OC(C)=O)cc1 +Cc1nc(C)c(C(=O)NCc2ncc(-c3ccccc3)o2)s1 +CCC(NC(=O)N(C)C(C)C)c1ccc(F)cc1F +COc1ccc(Cn2cccc2-c2nc(C)no2)cc1F +CC(C)CCC(=O)Oc1ccc(NC(=O)c2ccco2)cc1 +COc1cc(C)sc1C(=O)NCC(C)(C)c1ccncc1 +O=C(OCC(=O)N1CCCC1)c1cc(F)c(F)cc1Cl +CCN(CC1CCCCO1)C(=O)Nc1cccc2cnccc12 +NC(=O)c1cc(-c2csc(NC(=O)c3ccc(F)c(F)c3)n2)c[nH]1 +COc1cccc(C(=O)N(CCO)C(C)C)c1OC +CC(C)Nc1nc(-c2cc(C(C)C)nn(C)c2=O)cs1 +CCOC(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +COc1cccc(C(=O)N(C)Cc2nc(C)c3ccccc3n2)c1 +Cc1ccc(C(N)=O)c(OCC(=O)N(C)Cc2ccc(C)o2)c1 +Cc1nc(C2CC3CN(C(=O)C4CCOCC4)CC3O2)no1 +O=C(Nc1ccccc1SCC(F)(F)F)c1csnn1 +CCOc1ccc(NC(=O)CC(C)C)cc1CO +CC(NC(=O)c1ccco1)c1cc2c(cc1Cl)OCCCO2 +COC1C(CO)OC(n2cc(C)c(N)nc2=O)C1O +COCC(C)(O)CNS(=O)(=O)c1ccc(C)cc1C +CC(=O)Nc1ccc(NC(=O)c2c(C)cc(C)cc2C)cc1 +O=C(Cn1ccc2ccn(CC3CC3)c2c1=O)NCc1cccs1 +CC(Oc1cccc(OCc2nsc(N(C)C)n2)c1)C(N)=O +O=C1CC(c2ccccc2)N(Cc2cccc(O)c2)CCN1 +Cc1cc(C(=O)N2CCN(C(=O)c3cccs3)CC2)c(=O)[nH]c1C +COc1cccc(-c2cc(N)c(=O)n(CC(C)C)n2)c1 +O=S(=O)(Cc1cccc(Cl)c1)NCC1CCCO1 +COC(=O)CSc1ccnc(Cc2ccccc2)n1 +Cc1ccccc1CNC(=O)CCCn1sc2ccccc2c1=O +CC(=O)NCc1noc2c1CN(Cc1cnn(C)c1)CC2 +CCCc1nnnn1Cc1coc(-c2cccs2)n1 +CCc1nnsc1C(=O)Nc1cc(-c2ccc(C)s2)n[nH]1 +Cc1ccc(C(N)=O)cc1-c1ccc2ncccc2c1 +CNC(=O)CN(C)S(=O)(=O)c1cc(C(F)(F)F)ccc1Cl +CC(C)(C)OC(=O)N1CCCCC2CCC(=O)CC21 +Cc1ccc(C)c(OC(=O)Cc2c(C)nc3cc(=O)[nH]n3c2C)c1 +CCCc1cnc(C)nc1N1CCN(Cc2ccncc2Cl)CC1 +COCCn1cc(NC(=O)c2c[nH]nc2-c2ccccc2F)cn1 +CC(OC(=O)c1ccc2ncsc2c1)C(=O)NCc1ccccc1 +COc1cc2cc(C(C)O)c(=O)[nH]c2cc1Cl +CN(CCC(F)(F)F)C(=O)CCCn1cncn1 +Cc1csc(SCC(=O)N(C2CC2)C(C)C2CC2)n1 +CC(=O)Nc1ccc(NC(=O)C(C)Sc2ccccc2)cc1Cl +Cc1ccc(CCC(=O)Nc2cccc(O)c2)cc1 +CCCC(C)C(=O)N(C)Cc1cc(C#CCO)cs1 +COc1cc(C(=O)Nc2cc(-c3ccncc3)n[nH]2)cc2occc12 +CC(=O)N1CC(C(C)C)Oc2ccc(C(=O)CN)cc21 +CC1(c2ccccc2)CCCN(C(=O)C2(Cn3cccn3)CC2)C1 +CC1CCN(C(=O)C2CCN(c3ccc(C#N)cc3F)CC2)CC1 +O=C(NCCNC(=O)c1ccccc1O)c1ccc(O)c(Cl)c1 +Cc1cc(N)c(NC(=O)OC(C)(C)C)cc1N(C)C +Cc1nn(-c2ccccc2)nc1C(=O)N1CCOCC1 +CCNC(=O)C1CCCN(S(=O)(=O)c2ccc(C)c(Cl)c2)C1 +COCC(C)NC(=O)C(NC(=O)c1ccco1)C(C)C +CNC(=O)c1cccc(NC(=O)NC2Cc3ccccc3C2)c1C +O=C(Nc1ccc2c(c1)OCCO2)c1nn2cccnc2c1Cl +CC1CC(C)CN(C(=O)C(C)N2CCOC(C(N)=O)C2)C1 +COCCOC1CCN(Cc2sc(N(C)C)nc2C)CC1 +CCc1cccc(OCCN2CCN(C(=O)N(C)C)CC2)c1 +CC(C)OC(=O)c1cc2c(ccn2C)n1CCC#N +Cc1ccc(-n2[nH]c(C(=O)NCc3cc4ccccc4o3)cc2=O)cc1 +Cc1nc(C)n(CCNC(=O)c2ccc3nc(C)sc3c2)n1 +O=C(CN1C(=O)COc2cc(O)ccc21)NCC1CCCO1 +CCCN(CCC)C(=O)NCCc1nnc2n1CCCCC2 +CN(C)c1cccc2c(S(=O)(=O)N3CCCC3)cccc12 +CCCC(=O)NCCc1nc(N(C)C)ncc1-c1ccncc1 +O=C(CN1C(=O)COc2cccnc21)NCc1ccco1 +CCNC(=O)N1CCN(Cc2nnnn2-c2ccc(Cl)cc2)CC1 +CCCOc1ccc(CNC(=O)c2cc(NC(C)=O)ccc2O)cc1 +COc1cccc(N2CCN(C(=O)NC3CC3)CC2)c1 +CSc1ccc(OCc2nnc(-c3ccccc3)o2)cc1 +Nc1ccc(-c2nc3cc(Br)cnc3o2)cc1 +CC(C)(C)c1noc(CCCC(=O)N2CCC(C(N)=O)C2)n1 +Cc1ccc(C#N)cc1NC(=O)NC(C)c1ccncc1 +O=C(NCC#Cc1ccccc1F)c1cnccn1 +Nc1nc(Cn2cncn2)nc(N)c1Cc1ccccc1F +COC(=O)C1Cc2c(OC)cc(OC)c(OC)c2C1=O +Nc1ncnc2sc3c(c12)CCN(C(=O)c1cccc(Cl)c1)C3 +Cc1cc(N2CCC(=O)C2=O)ccc1Br +CC(=O)Nc1ccc(NS(=O)(=O)Cc2ccccc2Cl)cc1 +Cc1ccc(C(=O)CSc2nnc(C(C)(C)C)c(=O)n2N)cc1 +Cc1ccnc(C2CCCN2S(=O)(=O)N(C)C)n1 +Cc1ccc(CN(C(=O)CSc2nnc(N)n2C2CC2)C2CC2)o1 +CCc1nc2c(s1)C(N(C)C(=O)c1cccc(OC)c1F)CCC2 +Cc1cc(C(=O)Nc2cccn(Cc3ccc(F)cc3)c2=O)on1 +Cc1nc(C)n(CC(=O)NC(c2ccc(F)cc2)C(C)C)n1 +CCCCN(CC(N)=O)C(=O)c1ccc(-c2ccc(F)cc2)o1 +CC(C)(C)NC(=O)c1ccccc1NC(=O)NCC1CCOCO1 +COc1ccc2c(c1)CN(C(=O)Nc1ccc(F)cc1OC)CC2 +O=C(Cc1cccnc1)NC(c1cccc(F)c1F)C(F)(F)F +CCCC(=O)N(C)C(C#N)c1ccc(OC)c(OC)c1 +COc1ccc(S(=O)(=O)N2CCCC(C#N)C2)c(C)c1 +Cc1nc2cc(C(=O)Nc3ccccn3)ccc2n1-c1ccccc1 +CCOC(=O)CC(C)CNC(=O)c1c(C)oc(C)c1C +Cc1[nH]ncc1CCCNC(=O)C1CCCCCC1 +CC(C)(C)C(NC(=O)Nc1cccc(-n2ccnn2)c1)C(N)=O +CC1OCCN(C(=O)NC2CCCN(Cc3ccccc3)C2=O)C1C +COc1cc(C)ccc1OCC(=O)N1CCNC(=O)CC1 +Cc1ccccc1CNC(=O)NCc1cccc(Cn2ccnc2C)c1 +NC(=O)c1ccccc1NCC(=O)N1CCN(C(=O)C2CC2)CC1 +COC(=O)CCOc1ccc(-c2nc(C)cs2)cc1 +Cn1cc(C2CC2C(=O)OCc2cccc3c2OCCO3)cn1 +CCCNC(=O)C1CCCN1C(=O)c1cc(Cl)ccc1Cl +Cc1nnc(NC2CCCN(c3ncccn3)C2)c(C#N)c1C +CN(C(=O)CSc1nnc(-c2ccco2)o1)C1CCCCC1 +COC(=O)c1cc(CNC(=O)NC(C)CN2CCCC2=O)oc1C +O=C(Nc1ccc(-n2cncn2)c(C(F)(F)F)c1)c1cccs1 +O=C(NCc1ccccn1)Nc1cc(Cl)ccc1F +Cc1cccc(NC(=O)N2CCN(Cc3c(C)noc3C)CC2)c1 +COc1cccc(-c2nc3cc4c(cc3n2CCO)OCO4)c1 +COc1cc(C#N)ccc1OC(=O)c1c(C)noc1C +O=C(c1cnn(-c2ccc(F)cc2)c1C(F)(F)F)N1CCOCC1 +O=C(C1CCOC1)N1CCC2(CCCN(c3ncccn3)C2)C1 +O=C(Nc1ccccn1)c1cc(Br)ccc1F +N#CCCCSc1nnc(-c2c[nH]c3ccccc23)o1 +CCc1onc(C)c1NC(=O)Cc1ccc(F)c(F)c1 +COC(=O)C(C)n1c(N)nc2cc3c(cc21)OCCO3 +CCOC(=O)CN(C)C(=O)c1ccc(C(=O)N(C)C)cc1 +Cc1ccc(CC2Oc3cc(O)ccc3NC2=O)cc1C +Cc1nc(N2CCC(OCC(C)C)CC2)c2cnn(C)c2n1 +CCc1onc(C)c1NC(=O)Cc1coc2cc(OC)ccc12 +O=C(NCCc1ccc2c(c1)OCO2)c1ccc2[nH]cnc2c1 +CCc1noc(CN(C)C(=O)c2sc(C)cc2OC(F)F)n1 +CN(C(=O)C1CCN(c2cnccn2)CC1)c1ccc2ccccc2c1 +CN(CC(=O)OCC(=O)N1CCc2sccc2C1)c1ncccn1 +CCOC(=O)c1ccc(-n2nc(C)c(C(=O)OCC)c2C)cc1 +CCc1cccc(C)c1NC(=O)c1cc(C(N)=O)cn1C +O=C(CC1CCc2ccccc21)N(Cc1ccccn1)Cc1ccco1 +C=CCNc1ncnc(N(C)Cc2ccccc2)c1N +CCC(C(=O)N1CCCC1)n1cnc2nc3c(cc2c1=O)CCCC3 +NC(=O)c1ccc(Cl)cc1OCC(=O)NC1CCCCCC1 +COC(=O)c1cn(Cc2ccncc2)cc(F)c1=O +CCc1ccc(OCC(=O)N(C)CCOC)cc1 +Cc1ccc(NC(=O)NCCCN2CCCCCC2=O)cc1F +COc1cccc(OCC(=O)NCCc2cc(C)no2)c1 +Cn1ccnc(NCc2ccccc2COc2ccccc2)c1=O +c1ccc(-c2csc3ncnc(NCCNc4ncccn4)c23)cc1 +Cc1ccc(S(=O)(=O)NCC(=O)N(C)C)cc1C +CCN1Cc2nc(N3CCC(O)CC3)ncc2C1=O +COC(=O)C1CCN(C(=O)Cc2ccc[nH]2)CC1 +O=C1NCC2(CCCN(Cc3nccs3)CC2)O1 +Cc1cc(C)n2nc(C(=O)Nc3ccccc3C(=O)C(C)C)nc2n1 +Cc1nc2ccc(Br)c(S(N)(=O)=O)c2s1 +Cc1ncc(C(=O)N(C)Cc2ccccc2)c(N)n1 +CCc1nc2n(n1)CCCC2NC(=O)NCc1cccc(F)c1 +Cc1nc(C)c(CC(=O)Nc2cccc(-c3nnnn3C)c2)c(=O)[nH]1 +CCOc1nnc(CN2CCCN(C(=O)c3ccncc3)CC2)s1 +CC(C)C(CC(=O)N1CCOCC1)c1ccco1 +CN(CC(=O)N1CCN(c2nccs2)CC1)c1ccc(C#N)cn1 +CCn1cc(NC(=O)N2CCCC2CN2CC(C)OC(C)C2)cn1 +Cc1coc(-c2cccc(NC(=O)c3ccccc3-n3ccnn3)c2)n1 +COc1ccccc1C(O)c1cc(Cl)c2c(c1)CC(=O)N2 +O=C(NCC(O)CNc1ccc(Cl)cc1)c1ccccc1F +CC(C)(C)C(NC(=O)CCc1ccc(F)c(F)c1)C(N)=O +CCc1ccc(OC)c(S(=O)(=O)NCc2cccnc2)c1 +CNC(=O)C(CC(C)C)NC(=O)Cc1ccccc1Br +CCCNC(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +O=C1CCC2C(CCN2Cc2nccs2)N1CC1CC1 +COc1ccc(O)c(C(=O)N2CCOCC2C)c1 +COc1ccc(S(=O)(=O)NC(C)(C)C#N)c(C)c1 +COC(=O)c1cc(CNC(=O)c2cnn(C(C)(C)C)c2)oc1C +CCNS(=O)(=O)c1ccc(C)c(C(=O)N(C(C)C)C2CCC2)c1 +O=C(OCCOc1ccccc1)c1scnc1C1CC1 +COc1ccc(-c2cnc(Cn3cncn3)o2)cc1 +COc1c(Br)c(C(=O)N2CCCCC2C)nn1C +Cc1cnccc1C1NCCc2cccc(OC(F)F)c21 +O=C(NCC(O)c1ccco1)c1cc(-c2cccc(Cl)c2)on1 +CC1CCCN(C(=O)c2cnn(-c3ccccc3)c2C2CC2)C1 +CC(C)OCC(O)CNc1cccc(F)c1C#N +CN(C(=O)c1ccc(Cl)c(N2CCCC2=O)c1)c1ccccc1 +Cc1[nH]ccc1C(=O)NCc1nnc(-c2ccccc2)s1 +CCN(CCC(=O)OC)C(=O)Nc1cccc(F)c1 +O=C(NCCCc1nc2ccccc2[nH]1)NCC1(c2ccccc2)CC1 +COc1ccccc1OC(=O)CSc1ccc(F)cc1 +CC1CC(=O)c2cnc3nc(-c4ccncc4)nn3c2C1 +NC(=O)c1cnc(NC(=O)c2ccc(-n3ccnn3)cc2)s1 +CC(Cc1ccccc1)NC(=O)c1ccc(N)cc1 +CC(CC#N)N(C)C(=O)c1cnc(OCC(F)(F)F)c(Cl)c1 +Cc1ccc(NC(=O)N(C)C2CC2)c2cccnc12 +CN(C(=O)c1c(F)cccc1Cl)C1(C#N)CCCC1 +NC(=O)c1cccc(OS(=O)(=O)c2ccc(F)cc2Cl)c1 +COc1cc(NS(C)(=O)=O)ccc1N1CCCC1=O +CCC(C)CN(C)c1cc2c(cc1N)CCC(=O)N2 +CC(C)n1c(=O)oc2cc(NC(=O)Nc3ccc(F)cc3)ccc21 +CC(C)(C)OC(=O)N1CC(=O)CC1Cc1ccccc1 +O=C1CN(C(=O)CCc2ccsc2)c2ccccc2N1 +O=S(=O)(Oc1ccc(-n2cnnn2)cc1)c1ccccc1F +Cc1cc(C(=O)N2CCN(C(=O)c3cccc4ccccc34)CC2)on1 +CC(Sc1ccccc1)C(=O)Nc1ccc(C#N)cc1 +Fc1ccc(Cc2nnc3sc(-c4[nH]ncc4Cl)nn23)cc1 +CC(C)Cc1cc(-c2nc(-c3cccnn3)no2)n(C)n1 +Cc1cccc(-c2ccc(C(=O)NCCO)o2)c1C +CCc1cc(C(=O)NCc2nc3ccccc3[nH]2)sc1C +COc1cccc(NC(=O)c2cnn(-c3cccc(Cl)c3)c2)c1 +CCOC(=O)c1ccc(Nc2ncnc(NC(C)(C)C)c2N)cc1 +Cc1nc(C(C)N(C)C(=O)CCn2ccc(=O)[nH]c2=O)c(C)s1 +Fc1ccc(CN2CCOC(c3nc(-c4ccccc4)no3)C2)cc1 +NC(=O)C1CCC(CNC(=O)CCc2ccc3ccccc3c2)CC1 +CNC(=O)c1cccc(NC(=O)C(C)Sc2ccc(C)cn2)c1 +O=c1c2c3c(sc2ncn1CC(O)c1ccccc1)CCCC3 +CC(C)(C)C(C#N)NC(=O)CNc1ccc(C#N)cc1 +COc1ccccc1OCC(=O)Nc1ccccc1C(F)(F)F +O=C(Nc1ccccc1)Nc1nc(CCC(=O)N2CCCC2)cs1 +Cn1c(N)c(C(=O)Nc2ccccc2)c(=O)n(C)c1=O +CC(=O)Nc1ccccc1OCC(=O)N1CCCc2ccccc21 +Cc1nc2ccc(NC(=O)Cc3cccc4cccnc34)cc2o1 +O=c1cc(CSc2nnc(-c3cccs3)o2)occ1O +Cc1cccc(NC(=O)Nc2cccc3ccccc23)n1 +N#Cc1c(NC(=O)c2ccnn2C(F)F)sc2c1CCC2 +CS(=O)(=O)N1CCC(C(=O)Oc2ccc(C#N)cc2)CC1 +O=C1CCN(C(=O)OCc2ccccc2)CC1Cc1ccccc1 +O=C(NCCOc1cccnc1)c1cc(F)cc(Br)c1 +Cc1cc(C(C)Nc2ncnc3c2cnn3C)c(C)o1 +Cc1ccc(C(=O)N(C)Cc2csc3ccccc23)cn1 +N#Cc1ccc(OCCn2cnc3ccccc32)cc1 +CN(C(=O)CC(C#N)c1cccnc1)c1ccccc1 +N#Cc1nnn(-c2ccc(O)cc2)c1-c1ccccc1Cl +CC(=O)c1[nH]c(C)c(C(=O)N(C)CCOc2ccc(C)cc2C)c1C +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)CCC(C)(C)C +O=C(NCC1CCCO1)c1cc(-c2ccco2)nc2ccccc12 +Cc1csc(CNC(c2ccccc2)c2ccncc2)n1 +CN(C(=O)CNc1cccc(C#N)c1)C1(C#N)CCCCC1 +CCc1ccccc1NC(=O)CN(C)C(=O)CN1CCCCCC1=O +Cc1nnc2ccc(OCCNC(=O)Nc3ccccc3F)nn12 +CCN(C)C(=O)c1cccc(C(=O)Nc2cc(C#N)ccc2Cl)c1 +N#Cc1c(-c2ccccc2)cn(-c2ccc(F)cc2)c1N +Cc1ocnc1CNC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +Cc1ccc(SCCNc2ccc(C(=O)N(C)C)cn2)cc1 +COc1cccc(-n2ccnc2SCC(=O)NC(C)C)c1 +Cc1ccccc1NCCC(=O)NC(C)CN1CCOCC1 +COCC1c2c(cnn2CC2CC2)CCN1C(=O)c1cccn1C +CCCCc1nc2n(n1)C(C(=O)NCCc1ccccc1)CC(=O)N2 +Cc1noc(C)c1CN(C)C(=O)Nc1cnn(-c2ncccn2)c1 +COC(=O)C(NC(=O)Cc1ccc[nH]1)C(C)(C)C +Cn1nccc1C(=O)N1CC(=O)Nc2ccccc21 +Cc1ccc(-n2ccnc2S(=O)(=O)C(C)C(N)=O)c(C)c1 +O=C1OCc2ccc(NC(=O)N(Cc3nccs3)C3CC3)cc21 +CNC(=O)c1ccc(-c2nc3sc4c(c3c(=O)[nH]2)CCCC4)cc1 +COc1ccc(OC)c(NC(=O)CNc2ccc(C(C)=O)cc2)c1 +CCc1noc(CC)c1CNC(=O)CCC(C)(C)C +O=C(NCc1ccnc(OC2CCCC2)c1)c1cccs1 +CCCCNC(=O)C1C(C)=NC(C(=O)OCC)=C1C +Cc1csc(NC(=O)NCc2cn(-c3ccccc3)nn2)n1 +CCOC1CCN(C(=O)Nc2cccc(SC(F)F)c2)CC1 +CCc1onc(C)c1NC(=O)C(C)c1ccc(OC)cc1 +COc1ccc(CN(C)C(=O)c2cccc(OC)c2F)cc1C +CCN(CC(=O)NC(C)C)C(=O)c1cnc(C)cn1 +O=C(Nc1ccc(N2CCCCC2)c2ccncc12)c1ccc(=O)[nH]c1 +CCC1(C(=O)Nc2ccc3c(c2)COC3)CCCC1 +CCN(CCO)C(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +COc1ccc(C(=O)CN2CCOCC2)cc1N +COc1ccc(-c2c(N)nc(=O)[nH]c2C)cc1OC +Cc1nc(NC(C)c2ccccc2)cc(-c2ccccn2)n1 +NS(=O)(=O)c1ccc(CCNC(=O)COc2ncccn2)cc1 +CC#CCNC(=O)NC(C)c1cnn(Cc2ccccc2)c1 +COc1ccc(C(=O)NCCNC(=O)c2ccncc2F)cc1 +O=C(c1cc(Cl)ccc1Cl)N1CCC(c2ccccn2)C1 +CN(Cc1ccccc1)C(=O)C1CSc2nccc(=O)n2C1 +Cc1ccccc1Cn1cc(-c2ccncc2)cc1C(=O)NC1CC1 +Cc1ccc2cnn(CCC(=O)Nc3ccc4c(c3)OCCO4)c2c1 +Cc1ccc(C)c(C(=O)N2CCCC2C(=O)NCc2ccco2)c1 +O=C(c1ccncc1)N1CCn2c(-c3ccccc3)cnc2C1 +O=C(OCC(F)F)c1cc2c(nc3sccn32)s1 +CC(C)C(=O)Nc1cccc(NC(=O)c2csnn2)c1 +O=C(NCc1nc(-c2cccs2)no1)Nc1nccs1 +C#CCN(CC#C)Cc1nnc(-c2cc(C)oc2C)o1 +Cc1ccccc1C1C2C(=O)CC(C)(C)CC2=Nc2ncnn21 +Cc1ccc(C)c(N2CC(C(=O)NC(C)(C)C)CC2=O)c1 +C=CCOCc1cncc2c1CCN(C(=O)N(C)C)C2 +O=C(C1CC1)N1CCC(OCc2ccccc2F)CC1 +COc1ccccc1NCCC(=O)c1cc(F)ccc1OC +COCC(=O)Nc1nc2cc3c(cc2s1)OCCO3 +Cc1cc(C)nc(NC(=O)COc2ccc(Cl)cc2)n1 +Cc1cc(C)n(CCCNC(=O)NC2CCCc3occc32)n1 +CCOc1ccc(NC(=O)c2cc(Cl)c[nH]2)c(C)c1 +CC(=O)Nc1ccc(C)c(NC(C)C(=O)Nc2cccc(C#N)c2)c1 +CCCN1C(=O)C(C)(C)COc2cc(NC(=O)CC)ccc21 +O=C(NC1CCCN(C(=O)c2ccco2)C1)c1ccccc1F +COc1cc(-c2cc(=O)c3cc(O)ccc3o2)ccc1O +CNC(=O)C1CCCN(C(=O)Nc2cnccc2C)C1 +CC(=O)c1ccc(OCC(=O)N2CCCc3ccccc32)cc1 +Cc1cc(NCc2c(C)nn(C)c2Oc2cccnc2)ccc1F +O=C(c1cnccn1)N1CCC2(CC1)CCN(c1ncc(F)cn1)C2 +COc1ccc(F)cc1C(=O)Cn1nnc(-c2cccc(F)c2)n1 +Cc1ccc2nc3c(c(C(=O)NCc4ncn(C)n4)c2c1)CCCC3 +COc1c(-c2nncc(N)n2)cc(C)cc1C(C)(C)C +NC(=O)c1ccnc(N2CCN(Cc3ccc(F)cc3Cl)CC2)c1 +Cc1oc2nc(CNC3(c4ccccc4)CCC3)nc(N)c2c1C +CCC(NC(=O)Nc1ccccc1-n1nc(C)nc1C)C1CCCO1 +Cc1nc(NCCCn2nc(C)nc2C)c2nc(C)oc2n1 +CC(C)(C)n1cc(C(=O)NCCCS(N)(=O)=O)cn1 +CCn1cc(C(=O)Nc2ccc3oc(C)nc3c2)c(C(C)C)n1 +CC1CCC(CO)(NC(=O)C2CC(=O)N(C)C2)CC1 +CCC(=O)Nc1sc2c(c1C(=O)NC)CCN(C(=O)OC)C2 +Cc1cccc(OC2CCN(C(=O)c3c[nH]c(C)cc3=O)CC2)c1 +COC(CNC(=O)c1ccoc1)c1cccc(F)c1 +CCC(CC)c1nnc(NC(=O)NCc2ccc(OC)cc2)s1 +CC(=O)NCC(=O)NCC1(c2ccncc2)CCCCC1 +O=C(CC1CCCO1)Nc1ccccc1S(=O)(=O)N1CCCC1 +CCOC(=O)C(O)C(Cl)(CC)c1ccccc1 +Cc1nc(C2CN(C(=O)OC(C)(C)C)CCN2)cs1 +COC(=O)N(C)c1ccc(NC(=O)NCc2cccs2)cc1 +CC(C)(C)C(=O)Nc1nnc(C2CC(=O)N(c3ccccc3)C2)o1 +CC(O)CNC(=O)C1(N(C)Cc2ccccc2)Cc2ccccc2C1 +O=C(Nc1ccc2c(c1)CCC2)NC1CCN(c2ncccn2)CC1 +Cc1ccc(NC(=O)c2cn3cccnc3n2)nc1 +Cn1ccc2cc(C(=O)Nc3c(F)cccc3F)ccc21 +O=C(NCc1cn[nH]c1)c1ccc(Br)cc1 +Cc1noc(C)c1-n1c(-c2ccn(C)n2)n[nH]c1=O +COc1cccc(CC(=O)Nc2cccc(-n3nc(C)cc3C)c2)c1 +COCCN(Cc1cnn(C)c1)C(=O)c1cccc(Cl)c1Cl +Nc1ccc(C(=O)Nc2ccc(C(F)(F)F)cc2)nn1 +CC(C(=O)Nc1ccc2c(c1)COC2)c1cccnc1 +CCCn1c(C)nnc1SCc1nc2ccc(Cl)cc2c(=O)[nH]1 +Cc1cc(C(=O)NC(C)c2cnn(C)c2C)sc1C +COc1cccc(C(=O)Nc2ccccc2C(=O)NC2CC2)c1OC +Cc1ccc(N)cc1NC(=O)C(C)OCc1ccco1 +N#Cc1ccc(OCCCOc2ccccc2CO)cc1 +CC(C)c1c(C(=O)NCc2cccnc2)cnn1-c1ccccc1 +CC(Cn1cccn1)NC(=O)N1CCc2ccccc21 +C=CCN(CC=C)C(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +CCCNC(=O)c1cccc(C(=O)Nc2ccnc(C)c2)c1 +CCC(=O)Nc1ccc(NC(C)C(=O)NC(C)(C)C)cc1 +CNC(=O)CNC(=O)c1csc2c1CCCC2 +CC(NC(=O)N(Cc1ccc(F)cc1F)C1CC1)c1ccncc1 +CC1(C#N)CCN(c2nc3c(c(=O)[nH]2)Cc2ccccc2OC3)CC1 +O=C(c1ccccc1)N1CCCC(c2nc(-c3ccccc3)n[nH]2)C1 +COC(=O)c1cccc(S(=O)(=O)NC(CO)C(C)(C)C)c1 +OCCOc1ccccc1OCc1noc(C2CC2)n1 +CC1CCN(c2ccc(CCC(=O)N3CCOCC3)cc2N)CC1 +Cc1ccc(C)c(-c2c(C#N)c(N)n(N)c(=O)c2C#N)c1 +CC(=O)NCCNC(=O)N(C)Cc1ccc(Br)cc1 +CC(O)CNC(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +O=C(Nc1ccccc1)C1CC2CN(Cc3ccccc3)CC1O2 +Cc1c(C(=O)Nc2cc[nH]n2)nnn1-c1cccc2ncccc12 +C=CCCCN(C)C(=O)Nc1ccc(Cl)c(C(=O)NC2CC2)c1 +CC(CC(=O)Nc1nnc(C(F)(F)F)s1)c1ccccc1 +CC(C)Cc1cc(CN2CCN3CCN(C)C(=O)C3C2)n[nH]1 +Cn1cc(NC(=O)NC(CO)c2ccccc2)cn1 +COC(=O)c1ccccc1NC(=O)c1cc(F)ccc1F +CCN(CC)S(=O)(=O)c1cc(C)c2[nH]c(=O)cc(C)c2c1 +Cc1cccc(C)c1NC(=O)c1ccc(F)c(F)c1 +O=C(NC1CCOCC1)c1sccc1S(=O)(=O)N1CCCC1 +O=C(NCc1n[nH]c2c1CCC2)c1cc(-c2ccccc2O)n[nH]1 +Cc1cccc(C(=O)N(C)C2CCCCC2C)c1N +CSc1nc(C)cc(C(=O)Nc2ccc(-n3cccn3)cc2)n1 +c1ccc(-c2nc[nH]n2)c(OCc2cccc3cccnc23)c1 +CCCCC1C(=O)N(C)CCN1C(=O)c1ccc(-n2cnnc2)nc1 +Cc1ccccc1-c1nnc(SCC(=O)NC2CC2)n1C +CCOC(=O)C(NCc1cccs1)C1CCOC1 +Cc1nnc(NCc2ccc(N3CCCC3=O)cc2)c(C#N)c1C +O=C(C1CSc2nccc(=O)n2C1)N1CCC2(CC1)OCCO2 +CCCc1nnc(NC(=O)C(Cc2ccccc2)n2cnnn2)s1 +O=C(NCCNC(=O)C1CCC1)c1ccc(F)cc1 +COc1ccccc1OCC(=O)Nc1sccc1C(N)=O +COC(=O)C1CCN(C(=O)c2sccc2C)CC1 +COC1CCC(CC(=O)Oc2c(C)nn(C)c2C)CC1 +Nc1nonc1-c1noc(NCC2CCCO2)n1 +O=C(c1cccs1)N1CC2CN(c3ccsc3)C(=O)C2C1 +Cc1nnc(NC(C)C2CCCCC2)c(C#N)c1C +COc1ccccc1-c1n[nH]c(C2CC2)c1NC(=O)C1CCCC1 +CCOc1ccccc1NC(=O)CNC(=O)c1ccc(Cl)cc1 +CCSc1ccc(C(=O)N2CCC(O)(COC)C(C)(C)C2)s1 +N#Cc1cccc(OCC(=O)Nc2cccc(F)c2)c1 +Cc1cccc(C(=O)N2CCC(c3nnc4ccccn34)CC2)n1 +COc1ccc(NC(=O)NCc2ccc(C)cc2N(C)C)c(OC)c1 +Cc1noc(-c2cccn2Cc2cccc(C(F)(F)F)c2)n1 +Cc1cc(CN(C)C(=O)C(C)NC(=O)c2ccoc2)no1 +CCOc1cc(N)c(NC(=O)C(C)C)cc1OCC +COc1ccc(Nc2ncccc2C(N)=O)cc1Cl +CC(C)n1ncc2c1C(NC(=O)N(C)Cc1ccco1)CCC2 +Cc1ccc(-n2ccnc2)c(C(=O)N(C)Cc2ccc(F)c(F)c2)c1 +Cc1ccn(-c2ccc(NC3CC4CCC3O4)nn2)n1 +O=C(CC1CSc2nccc(=O)n21)N1CCCCCC1 +CCCOCC(=O)Nc1cc(S(=O)(=O)NC)ccc1C +NC(=O)C1CCCN(c2ncnc3sc4c(c23)CCCC4)C1 +N#CCCN(Cc1cccnc1)C(=O)c1cnccn1 +CNC(=O)C1CCCCN1C(=O)c1cc2cc(OC)cc(OC)c2[nH]1 +CCN(CC(=O)OC)C(=O)c1c(C)c(C)n[nH]c1=O +O=C(Cn1nnc(-c2ccc(Cl)cc2)n1)Nc1ccc(F)cc1 +CCn1ncc(CN(C)c2nc(C)cc(C(F)(F)F)n2)c1C +CCOc1ccc(CC(=O)Nc2cc(C)nn2C(C)C)cc1 +CCS(=O)(=O)N1CCC(C(=O)Nc2cc(F)ccc2C)CC1 +N#Cc1cccc(NC(=O)CS(=O)(=O)c2ccccc2F)c1 +O=C(Nc1cc(C2CC2)nn1-c1ccccc1)C1CCOC1 +CN(Cc1ccccc1)C(=O)NCc1cc(=O)[nH]c2ccccc12 +CCCC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCOCC2)c1 +COC(=O)N1CCC(NC(=O)Cc2cn3ccsc3n2)CC1 +CC(C)(C)CCOC(=O)c1cccc(N2CCCC2=O)c1 +NS(=O)(=O)c1ccc(NCCc2cccs2)cc1 +CCOc1ccc(F)c(C(=O)N(C)C(C)Cc2ccsc2)c1F +Cc1cccc(C2(C(=O)N3CCC(CC(N)=O)CC3)CCCC2)c1 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+COc1ccc(C)cc1NC(=O)NCCC(=O)N(C)C +C#CCOc1ccc(N(C)C(=O)c2cn(Cc3ccccc3)nn2)cc1 +CC1Cc2ccccc2N1C(=O)Cc1csc(NC(=O)C2CC2)n1 +CCc1ccccc1NC(=O)Cn1cnc(C)cc1=O +COC(=O)c1cc(CNC(=O)Nc2nccs2)oc1C +Cn1c(C(=O)NCC(=O)NCCCn2cccn2)cc2occc21 +O=C(CCc1ncc(-c2c(F)cccc2F)o1)NCCc1ccco1 +O=C(NCCc1c[nH]c2ccccc12)c1ccc(=O)[nH]c1 +CCCc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 +NC(=O)Cn1cc(NC(=O)CCOc2ccc(Cl)cc2)cn1 +O=C(CCC(=O)N1CCc2cc(F)ccc2C1)c1cccs1 +CCN(CC)C(=O)c1cccc(NC(=O)c2ccc(=O)n(C)n2)c1 +Cc1ccc(CNc2cc(C(N)=O)ccc2F)cc1 +N#Cc1ccccc1Oc1ccc(C(=O)N2CCC(O)C2)cc1Cl +O=C(Nc1ccc2c(c1)OCO2)c1cc2ccccc2oc1=O +Cn1cc(CNC(=O)c2cc(-c3ccc(F)cc3)[nH]n2)cn1 +O=C(CCC1CCCC1)N1CCN(C(=O)C2CCC2)CC1 +Cc1cccc(C(C#N)CC(=O)Nc2cccc(C#N)c2)c1 +Cc1ccccc1CNC(=O)CC1Sc2ccccc2NC1=O +CCC(c1nc2ccccc2n1CCO)N1CCOCC1 +Cc1n[nH]c(C2CN(C(=O)c3ccc(N(C)C)nn3)CCO2)n1 +CCn1c(=O)n(CC(=O)N(CC(=O)OC)C(C)C)c2ccccc21 +O=C(Cc1c(F)cccc1Cl)NCc1ccco1 +O=C(Cc1ccc[nH]1)NCC1(c2ccc(F)cc2)CC1 +CCC(=O)Nc1cc(NCC(=O)Nc2ccccc2)ccc1C +O=C(Nc1cc(O)cc(F)c1)C1OCCc2ccccc21 +CCOc1c(O)ccc2c1C(c1ccc(N)cc1)NCC2 +CCCC(=O)NCC1CCCN(C(=O)C2Cc3ccccc3O2)C1 +CCCn1c(O)nnc1SC(C)C(=O)NCc1ccccc1F +Cc1ccc2c(c1)oc(=O)n2C(=O)c1cccs1 +COCc1ccccc1NC(=O)Nc1cccc(C(C)OC)c1 +Cc1nc(-c2ccc(Oc3nccc(C(F)(F)F)n3)cc2)no1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NC(C1CC1)C1CC1 +Cc1ccccc1S(=O)(=O)C(C)C(=O)Nc1c(C)cccc1C +O=C(Nc1cccc(-c2cn[nH]c2)c1)C1CCN(c2cnccn2)CC1 +COc1ccc(CNC(=O)Nc2ccc(F)c(C#N)c2)cn1 +Cc1ccc(OC(=O)C2CCCO2)c(C(=O)NCC(C)C)c1 +O=C(NCc1cc2ccccn2n1)C1CC(=O)N(c2ccccc2)C1 +CC(=O)Nc1ccc(Nc2cccc(F)c2C#N)cc1 +CCCN(C(=O)c1cnc2onc(C)c2c1)C1CCc2ccccc2C1 +Cc1noc(CC2COC3CN(C(=O)c4ccncn4)CC23)n1 +CC(=O)N1CC2CC3C(C1)(CN(Cc1cccnc1)S3(=O)=O)O2 +CC(C)(C)C(COc1ccccc1F)NC(=O)c1c[nH]nn1 +COCCN1CC(C(=O)NCc2c(C)cc(C)[nH]c2=O)CC1=O +Cn1cccc1C1CCCCN1C(=O)Cc1ccc(F)c(F)c1 +CCC1CN(S(=O)(=O)c2ccc(C(C)=O)cc2)CCO1 +CCC(=O)CCn1cnc2sc(C)cc2c1=O +Cc1noc(C)c1C(=O)N1CCCC1c1nc2ccccc2s1 +CNC(=O)Oc1c(C)cc(Cl)cc1Br +COc1ccc(C)cc1NC(=O)COc1ncnc2ccccc12 +COc1ccc(CC2NCCc3ccc4c(c32)OCO4)cc1 +O=C(COC(=O)c1ccccc1O)NCCc1c[nH]c2ccccc12 +O=C(Cn1nc2n(c1=O)CCCCC2)OCCCc1ccccc1 +COCCN1CC(C(=O)Oc2c(C)cc(C)cc2C)CC1=O +O=C(C1COc2ccccc21)N1CCc2cc(F)ccc2C1 +NC(=O)C1CCN(C(=O)Nc2ccccc2C(F)(F)F)C1 +O=S(=O)(CC1CCOCC1)N1CCc2cc(F)ccc2C1 +CC(C)(C)OC(=O)N1CCCC1(C)C(=O)Nc1ccc2c(c1)COC2 +CC1CCN(C(=O)C(C)n2nc(-c3ccccc3)ccc2=O)CC1 +CC(C)N(C)S(=O)(=O)N1CCCC1CC(=O)c1ccc(F)cc1 +CCc1ccc(S(=O)(=O)N2CCC(O)CC2)cc1 +CCc1nnc2n1CCN(C(=O)C1CC(=O)N(c3ccccc3)C1)C2 +COc1cc2nc(NC(=O)c3ccccc3)sc(=O)c2cc1OC +O=S(=O)(c1cn[nH]c1)N1CCN(CCO)CC1 +CC(C)C(NC(=O)c1cnc2ccoc2c1)C(=O)Nc1nccs1 +C=C(C)COc1ccc(C(C)=O)cc1NC(=O)C1CCC1 +Cn1ccc(C(=O)NCCCOCC(F)(F)F)cc1=O +CC(C)NC(=O)c1cc(-c2ccco2)n(-c2ccc(Cl)cc2)n1 +CCCc1ccc(NC(=O)CCC2C(=O)N=C(C)N=C2C)cc1 +NS(=O)(=O)CCNC(=O)Cc1ccc2c(c1)CCCC2 +CN(CCc1ccccc1)C(=O)c1cnn(-c2ccc(Cl)cc2)c1 +CCC(O)CN1CCN(C(=O)c2cc3c(s2)CCOC3)CC1 +NC(=O)C1Cc2ccccc2N1S(=O)(=O)c1cccs1 +CCOC(=O)c1cnc2nc(C)ccc2c1Nc1ccc(O)cc1 +CC(C)CNC(=O)c1cnc(C2CCCO2)nc1N +O=C(Nc1ccc(OC(F)(F)F)cc1)c1ccn2cncc2c1 +O=C(NC1CC(=O)N(CC2CCCCC2)C1)c1cc[nH]n1 +CC(CCC1CCCO1)NC(=O)NCc1cc(F)ccc1F +CCCn1c(C)ccc(-c2csc(NC)n2)c1=O +CN(C)C(=O)Cn1cnc(NC(=O)NCC(C)(C)c2ccncc2)n1 +CC(C)N(C(=O)CCCSc1ccccc1)C1CCOCC1 +Cc1noc(C)c1CC(=O)N1CC(c2nc(-c3cccnc3)no2)C1 +Cn1cnc2cc(OC(=O)CNC(=O)c3ccccc3)ccc21 +Cc1cnc2c(S(=O)(=O)Nc3ccccc3)cccc2c1 +CC1CN(C(=O)CSc2nnc(C(C)(C)C)n2N)CC(C)O1 +CC(C)Oc1ccc(CNC(=O)c2ccc(-n3cncn3)nc2)cc1 +O=C(CCC1NC(=O)c2ccccc2NC1=O)Nc1ccncc1 +COCCOc1ccc(F)cc1NC(=O)c1cc(C2CC2)on1 +CC(C)CNC(=O)CSc1ccc(Cl)cc1N +Cc1cc(-n2nc(C)c(Br)c2C)ccc1CO +COC(=O)C1CCCc2nc(-c3ccccc3OC)nn21 +COc1ccc(C(=O)N2CCCC(Cc3nccs3)C2)cc1 +Cc1ccc(-c2nnn(CC(=O)N3CCOc4ccccc43)n2)cc1 +Cc1cc2[nH]c3c(c(=O)n2n1)CCN(Cc1cccc(F)c1F)CC3 +Cn1ncc2c1CCCC2NC(=O)C1CC(=O)Nc2ccccc21 +CCCc1cc(C(=O)NC(C)c2ccc(-n3cncn3)cc2)no1 +COC(=O)c1cc(-c2cc(C)ccc2S(C)(=O)=O)on1 +Fc1ccc(CNCc2ccccn2)c(F)c1Cl +Cc1nc(CN(C)C(=O)NCc2ccc(F)cc2)cs1 +CC(C)COC(=O)C(C)n1c(=O)oc2ccc(CO)cc21 +Cc1nn(C)c2c(=O)n(CC(=O)NC3CCCC3)nnc12 +O=C(CCOc1ccccc1)N1CCCc2ccccc21 +COCCNC(=O)N1CCC(n2c(C)nc3cccnc32)CC1 +O=C(c1ccc(F)cc1)N1CCC2(CC(Oc3cccnc3)CO2)C1 +Cc1c(C(=O)NCCn2cnc3ccccc32)[nH]c2c1C(=O)CCC2 +CCOc1ccc(NC(=O)CCn2ccccc2=O)cc1F +CS(=O)(=O)N1CCCN(C(=O)c2cc(F)cc(F)c2)CC1 +O=C(NCCC(=O)N1CCOCC1)c1ccc2ccccc2c1 +O=C(Nc1nccs1)c1cccc(Oc2ncccn2)c1 +CCOc1ccccc1C(CC)NC(=O)C1CC=CC1 +Cc1cnc(C(=O)OCC(=O)Nc2ccc(F)c(F)c2)cn1 +CCc1nn2c(CO)c(-c3ccc4ccccc4c3)nc2s1 +COC(=O)C1(C)CCCN(C(=O)OC(C)(C)C)C1 +Cc1ccc(CNC(=O)C(NC(=O)c2cccs2)C(C)C)cc1 +Cc1cc(NC(=O)c2ccc(C#N)cc2)c2ccccc2n1 +O=C(C(O)C1CCCCC1)N1CCCN(c2ccc(F)cc2)CC1 +CCOC(=O)CC(C)CNC(=O)c1n[nH]c(=O)c2ccccc12 +CCNS(=O)(=O)c1cc(NC(C)=O)c(C)cc1C +CC(OC(=O)c1cccnc1)C(=O)Nc1ccc(Cl)cc1 +Cc1cccc2c(=O)n(CCC(=O)NC3(C(N)=O)CCCC3)cnc12 +CCN(CC(=O)N(C)C)C(=O)c1ccc(Br)cc1O +Cc1ccnc(NCC2CCCCN2C(=O)OC(C)(C)C)n1 +CC(C)Cn1c(SCCCO)nnc1-c1ccccc1F +COCCCn1c(-c2cccs2)ccc(C#N)c1=O +N#Cc1ccc(-c2noc(CCC(=O)c3ccc(F)cc3)n2)nc1 +CCNC(=O)CN1CCN(C(=O)NC(c2ccccc2)C2CC2)CC1 +Cc1nc2c(c(NC3CCNC3=O)n1)Cc1ccccc1OC2 +CNC(=O)c1cccc(C(=O)N2CCN(CC3CC3)c3ccccc32)c1 +Cc1nn(Cc2cccc(F)c2)c(C)c1S(N)(=O)=O +O=S(=O)(NCCCO)c1c(F)cc(F)cc1Br +CCOc1c(Cl)cc(C(=O)NCCNC(C)=O)cc1OC +O=C(C1CNCCN1C(=O)C1(Cn2cccn2)CC1)N1CCCC1 +CCc1cc(NC(=O)c2cc3ccccc3[nH]2)[nH]n1 +CC(=O)NCCNC(=O)NC(c1ccccc1)c1ccc(C)cc1 +CC(C)(C)CC(C)(C)NC(=O)NCc1ccncc1 +CCN(CCO)C(=O)Nc1cc(C(=O)NC)ccc1Cl +O=C(NCC#Cc1ccc(F)cc1)c1cc(-c2cccs2)n[nH]1 +CCSc1ccc(-c2ccc3c(c2)OCO3)nn1 +Cc1cc(NCc2coc(-c3ccccc3)n2)no1 +COc1cccc(CN2CCOC(Cc3cccc(F)c3)C2)c1OC +Cc1ccc(C(C)NS(=O)(=O)c2cccc3nonc23)cc1 +CN(Cc1ccc(O)cc1)C(=O)Nc1ccncc1 +CCc1ccccc1NC(=O)NCc1c(C)nn(C)c1C +COc1ccc(CNC(=O)N(C)C(C)C)c(OC)c1OC +O=C(Nc1ccc(F)c(F)c1)C1CN(C(=O)c2cnccn2)C1 +COc1cc(S(=O)(=O)NCc2ccccc2)c(OC)cc1C +CCc1ncc2c(n1)CN(Cc1nc3ccccc3s1)CC2 +CC(C)C(=O)OCC(=O)Nc1ccc(OC(F)F)c(Cl)c1 +CCCn1nnnc1COc1cccc(-n2ccnc2)c1 +CCN(C)C(=O)c1cccc(OC(=O)CCn2c(C)csc2=O)c1 +CC(=O)c1sc(N(C(=O)c2ccccc2Cl)C2CC2)nc1C +CCCC1CN(C(=O)c2ccc(OC)c(F)c2)CCO1 +Cc1cc(NC(=O)c2ccc(C(C)(C)C)cc2)n(C)n1 +NC(=O)c1cccc(OCc2ccc(Cl)cc2)c1 +CC(=O)N1CCc2c(c(-c3ccc(N)cc3)nn2CCC#N)C1 +Cc1cnc(C(=O)Nc2nc3ccccc3s2)cn1 +CCC1CCCN(C(=O)c2nnn(-c3ccc(C)cc3)c2C)C1 +Cc1cc2nnc(SC3CCN(c4ccccc4)C3=O)n2c(C)n1 +CCCc1nnc2sc(Cc3ccc(S(C)(=O)=O)cc3)nn12 +O=C(NCCc1ccc(F)cc1)c1c[nH]c2cccc(F)c12 +Nc1cccc(Cl)c1SCC(=O)NCC1CC1 +CCC(NC(=O)CNc1cccc(C(=O)N(C)C)c1)c1ccccc1 +C#CCOc1ccc(NC(=O)c2cnn(-c3ccncc3)c2C)cc1 +CCS(=O)(=O)N1CCC2(CC1)CC(=O)c1ccccc1O2 +O=C(CCNC(=O)C1CCCC1)Nc1c(F)cccc1F +CC(NC(=O)CCCc1cccs1)C(=O)NC(C)(C)C +Cn1ccc(C(=O)N2CCCC(c3cc(CO)[nH]n3)C2)n1 +O=C(NCCc1nnc2n1CCCCC2)c1ccccc1Cl +O=C(c1ccccc1F)N(CCO)C1CCCCC1 +CCn1c(NC(=O)C(C)n2cnc3ccccc32)nc2ccccc21 +CCn1cc(C(=O)Nc2cccc(C)c2)c(=O)c2cc(OC)ccc21 +CC(=O)c1ccc(OC(=O)CCC2CCCOC2)c(C)c1 +COc1cccc(OC)c1OCC(=O)Nc1cccc(C)c1 +COc1ccccc1NC(=O)c1nccc2c(N)cc(C)cc12 +COCC(C)(O)CNC(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +COc1ccc(Cl)cc1C(CC(N)=O)CC(C)C +Cc1ccc(NC(=O)CNc2ccc(C(=O)N(C)C)cc2)cc1 +Cc1cccc(OCC(=O)Nc2ccc(N)c(F)c2)c1C +O=C(CCSc1nncs1)Nc1cccc(Br)c1 +Cc1cc(C)c(NC(=O)c2cc(N)ccn2)c(C)c1 +CCOc1ccc(CC(=O)Nc2cccc3cnccc23)cc1 +Cc1ccc(NC(=O)CCSc2nnc(C(F)(F)F)n2N)cc1 +O=C1CCc2cc(NC(=O)NCC3CCC3)ccc2N1 +O=C1NC2(CCN(C(=O)c3ccccc3F)CC2)Oc2ccccc21 +Cn1ccnc(NC(=O)CCc2cc(F)ccc2F)c1=O +CC(C)CCOC1CCCCC1NC(=O)c1nccnc1N +Cc1nccc(C(=O)N2CC(C)(C)Sc3ccccc32)n1 +COc1ccc(Br)cc1CNC(=O)C1CCC(=O)N1 +CCN(CC)S(=O)(=O)c1ccc(SC(C)C)nc1 +Cn1nnnc1-c1cccc(NC(=O)CCn2cncn2)c1 +CCOC(=O)CC(O)(Cc1ccccc1)c1ccccc1 +CCc1nc(C)c(-c2nnc(NCC(C)C)s2)s1 +Cc1ccc(NC(=O)c2c(C)c(N)c(C)[nH]c2=O)c(C)c1 +COc1ccc(OC)c(CCNC(=O)Cc2c(C)n[nH]c2C)c1 +Nc1ccc2c(NCCC(=O)NCc3ccccc3)ncnc2n1 +C#CCC(C)C(=O)c1ccc2c(c1)N(CC)C(=O)CO2 +CCOCC(=O)N1CCC(c2nnc(Cn3cccn3)n2C)CC1 +CN(C(=O)c1cccc(F)c1F)c1cccc(F)c1 +CC(NC(=O)c1cnccn1)C(=O)N1CCCCC1 +COc1ccc(CNC(=O)NC(C)Cc2cccs2)cc1 +O=C(NCCNc1ncccn1)c1cc2c(s1)CCCC2 +OCc1nnn(-c2ccc(F)cc2)c1CCOc1ccccc1 +Cc1cc(C)n(CC(=O)NC(c2ccc(F)cc2)C2CCCO2)n1 +CN(C(=O)c1onc(-c2ccccn2)c1N)c1ccccc1 +CCOc1ccccc1CN(C)S(=O)(=O)c1cnn(C)c1 +Cc1cccn2cc(CSc3nncn3-c3ccccc3)nc12 +CNS(=O)(=O)c1cc(NC(=O)NC(C)(C)C)ccc1C +COc1cccc(NC(=O)NCCc2ccncc2)c1 +Cc1cnc2c(c1)nc(-c1ccc(C)c(C)c1)n2CCC#N +Cc1cc(NC(=O)N2CCN(c3nc4ccccc4o3)CC2)n(C)n1 +CC(NS(C)(=O)=O)C(=O)Nc1ccccc1Oc1ccccc1 +O=C(Cc1c[nH]c2ccccc12)N1CCc2ncncc2C1 +CN(C(=O)OC(C)(C)C)C1CCN(C(=O)NC2CCOCC2)CC1 +O=c1c2cc(Br)cc(Br)c2ncn1CCO +Cc1c(-c2ccc(O)cc2)nc(N)c(C#N)c1-c1cnc(N(C)C)nc1 +COC(=O)Cn1nc2c3c(C)c(C)sc3ncn2c1=O +CCc1cc(CNC(=O)N2CCc3ccccc3C2CO)[nH]n1 +CC(C)N(Cc1cnn(C)c1)C(=O)Cc1c[nH]c2cc(Cl)ccc12 +Cc1nc(SCC(=O)c2ccccc2)sc1C +Cc1n[nH]cc1NC(=O)c1cc(Cl)cc(Cl)c1 +CC(=O)N1CCN(C(=O)CCc2nc3ccc(F)cc3[nH]2)CC(O)C1 +N#Cc1cccc(NC(=O)CC(C#N)c2ccccc2)c1 +Cc1cccc(C)c1NC(=O)CSc1cccc2cccnc12 +Cc1ccc(NC(=O)Cn2nc(C)c3c(C)onc3c2=O)cc1F +CCC1c2ccccc2CCN1Cc1cnnn1C +COc1cccc(C(=O)OC(C)C(=O)Nc2ccccc2F)c1O +Cc1cnc(C(=O)Nc2cc(C(=O)N(C)C)ccc2Cl)cn1 +CC(=O)c1cccc(NC(=O)C(C)Sc2nnnn2C)c1 +CCN(C)C(=O)CNC(=O)c1ccc(OC)c(OC)c1 +COCCCNC(=O)c1ccc2c(OC)n(C)nc2c1 +COC(=O)c1ccc(CCNC(=O)c2cc(Cl)c[nH]2)cc1 +CCCN(C)C(=O)c1cc(OC)c(OC)cc1C +Cc1cc(CN2CCN(Cc3nc(C)no3)CC2)on1 +COc1cc(C(=O)OCc2sc(C)nc2C)cc(Cl)c1OC +COCc1nc2ccccc2n1CCOc1cccc(N)c1 +CCOCC(=O)N1CCC(Oc2ccc(C)nc2)CC1 +CC(C)NC(=O)C(C)(C(F)(F)F)C(F)(F)F +O=C(NCC(=O)N1CCOCC1)c1ccc(N2CCCC2=O)cc1 +CC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2ccc(N(C)C)cc2)c1C +CC(=O)NCCCC(=O)NC1CC(=O)N(C2Cc3ccccc3C2)C1 +COc1ccc(C2(CNC(=O)c3snnc3C)CCOCC2)cc1 +FC(F)(F)CSc1nnc(C2CC2)n1-c1ccccc1 +COC(=O)NCc1ccc(NCC(=O)Nc2cc(C)nn2C)cc1 +COc1cc(C(C#N)N(C)C(=O)OC(C)(C)C)ccc1O +CC(C)n1nccc1NS(=O)(=O)c1cccc(C#N)c1 +Cn1cc(CNS(=O)(=O)c2ccc(Cl)cc2F)cn1 +Cc1[nH]ncc1S(=O)(=O)Nc1ccc(Cl)cc1 +O=C(CSc1nncn1-c1ccccc1)Nc1ccccc1F +CCN(CC(F)(F)F)c1c(CO)c(C)nn1C +CC(O)CNC(=O)C(NC(=O)c1ccc(Cl)cc1Cl)C(C)C +Cc1cc(S(N)(=O)=O)cc(NC(=O)N2CC(C)CCC2C)c1C +O=C(NCc1ccc(OCC(F)(F)F)nc1)NCc1cscn1 +N#Cc1ccc(-c2noc(Cc3ccccc3C(F)(F)F)n2)nc1 +Cn1cnc(CNC(=O)N2CC(C)(C)c3c(Cl)cccc32)n1 +CCN(C1CCN(C(=O)c2cccc(Cl)c2)CC1)S(C)(=O)=O +Cc1cc(C(C)NC(=O)c2cn(Cc3ccccc3)nn2)c(C)s1 +COc1cccc(NC(=O)CCc2ccc(OC)c(OC)c2)c1 +Fc1c(F)c(F)c(NCCc2ccco2)c(F)c1F +COc1ccc(C(C#N)NCc2cccc(C)c2)c(OC)c1 +Cc1ccc2oc(C(=O)NC(C)c3nnc4ccccn34)cc2c1 +Cc1nc2cc(C3NCCNC3=O)ccc2n1C(C)C +Cc1nc(C)c(CCC(=O)N(C(C)C)C2CCCC2)c(=O)[nH]1 +Cc1cc(OCC(=O)NC2CC2)cc(C)c1Cl +CN1CCN(C(=O)CN(c2ccccc2)S(=O)(=O)N(C)C)CC1 +O=c1n(Cc2ccccc2)c2ccncc2n1Cc1ccc(CO)cc1 +COc1ccc(OC)c(-c2nc(C)c(CO)s2)c1 +CCC(c1ccccc1)N(CC(=O)OC)C(=O)c1cccnc1 +CC(C)COCCNC(=O)N1CCC(c2nnc3ccccn23)CC1 +Cc1nnc(SCC(=O)NC2CCCC(C)C2C)s1 +CC(C)OCCCNc1ncnc2onc(-c3cc(F)cc(F)c3)c12 +CCCn1cc(CCNC(=O)c2ccc(F)c(F)c2)c2cccnc21 +Cc1cnc(C(=O)NCCC(=O)N2CCCc3ccccc32)cn1 +O=C(Nc1nc(C2CC2)cs1)c1c[nH]nc1-c1cccc(Cl)c1 +COc1ccccc1N1CC(C(=O)NCc2ccccn2)CC1=O +Cc1noc(C)c1CC(=O)Nc1cccc(OCc2ccccn2)c1 +CC(C)(C#N)C(=O)NCCc1c[nH]c2ccccc12 +COC(C)(C(=O)Nc1ccc(F)c(C(N)=O)c1)c1ccccc1 +O=C(NCc1ccncc1)c1ccc(N2CCCOC2=O)cc1 +Cc1ccc(Sc2ccc(N)cc2C(N)=O)c(C)c1 +COc1ccc(S(=O)(=O)N(C)C2(C(N)=O)CCCC2)c(C)c1C +Cc1nn(C)c(C)c1NC(=O)COCc1nc(-c2ccccc2)no1 +CCCN(CC(=O)NC)C(=O)c1cc(Br)cn1C +Cc1cc(CN(C)C(=O)Cn2c(=O)c3c(ncn3C)n(C)c2=O)no1 +O=C(c1ccoc1)N1CCn2cnc(COCC3CC3)c2C1 +Cc1ccc(C(=O)NCCC(=O)N2CCCc3ccccc32)cc1F +COc1c(F)cc(NC(=O)C2CC=CCC2)cc1F +CCC1CCC(CNC(=O)CSc2nccn2C)CC1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NCCC1=CCCCC1 +CCSc1ccc(NC(=O)NCCN2CCOCC2)cn1 +Cc1cc(C2CCCN2C(=O)c2cnc(Nc3ccccc3)nc2)on1 +COc1ccc(C)cc1-c1csc(NC(=O)c2ccoc2)n1 +COc1ccccc1C1CC(C(F)F)n2nc(C)cc2N1 +N#Cc1ccc(NCC(=O)Nc2ccccc2OC(F)F)cc1 +COCCNc1nc2c(c(=O)[nH]c(=O)n2C)n1C +Cc1cccc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)n1 +N#Cc1cccnc1NCCc1ccc(OC(F)F)cc1 +CCCn1ccc(NC(=O)c2cccc(C#N)c2)n1 +Cc1ccc(-c2cnc(CNCc3ccccc3)s2)s1 +CCOC(=O)CSc1nccc(N(C)C)c1C#N +CC1(C)OCC2(CO1)CN(C(=O)c1cncc(Br)c1)C2 +O=C(c1c(-c2ccc(F)cc2)nc2n1CCS2(=O)=O)N1CCCC1 +CS(=O)(=O)N1CCC(CNC(=O)c2c(F)cccc2Cl)CC1 +N#CC1CCN(C(=O)c2c(F)cccc2Cl)CC1 +Cc1ccc(CNc2oc(-c3ccco3)nc2C#N)cc1 +CCC(CC)N(CC(F)(F)F)C(=O)c1cn[nH]c1 +O=C1CCN(C(=O)Cn2cc(Br)c(=O)[nH]c2=O)CC1 +Cc1cnc(C(=O)Nc2ccc(Cl)cc2O)cn1 +CCc1cnc(C(C)NC(=O)N2CCOCC2C2CC2)s1 +Cc1ccc(C(C)N(C)C(=O)C2CCN(c3ncccn3)CC2)s1 +CC(C)N1C(=O)C(=O)c2cc(Cl)cc(Br)c21 +O=C(c1ccc2c(c1)OCO2)N1CCC(c2ccccc2F)CC1 +N#Cc1nc(C2CC2)oc1N1CCN(C(=O)C2CCCO2)CC1 +CC(NC(=O)c1ccn(-c2cccc(F)c2)n1)C(C)(C)C +COc1ccc(-c2nc(C(=O)NCCc3nncn3C)cs2)cc1 +OCC(O)Cn1ccnc1-c1ccccc1Br +Cc1n[nH]c(=O)nc1N1CCC2(CC1)OCCO2 +CCc1cccc(NC(=O)NCc2ccnn2C)c1 +CCC(C)C(C)(O)CNC(=O)c1c(C)noc1-c1ccccc1 +CCOc1nnc(Cn2c(-c3ccccc3)noc2=O)s1 +CN1CCN(C(=O)CCCS(N)(=O)=O)CC12CCNC(=O)CC2 +CCCNC(=O)CNC(=O)NCc1ccnc(OC)c1 +CCc1ccccc1NC(=O)N(CCO)Cc1ccccc1 +CC(=O)Nc1ccc(CNC(=O)CNCc2snnc2C)cc1 +O=C(Nc1ccncc1)C12CC3CC(C1)CC(n1cncn1)(C3)C2 +COc1ccc(Cl)cc1C(=O)CN1CCOC(C)C1 +CCn1cc(C#N)c(=O)n(Cc2cn3ccccc3c2C#N)c1=O +CC(C)CC(C)(NS(=O)(=O)N1CCC(C(C)(C)C)CC1)C(N)=O +Cc1ccc(-c2cc(COC(=O)c3cccn(C)c3=O)no2)cc1 +O=C(c1cccc(-n2cnnc2)c1)N1CCCC1c1cccnc1 +CC(CO)(CO)NC(=O)Cc1cc(F)ccc1Br +CC(Sc1ccccc1)C(=O)Nc1cc(N)ccc1F +Cc1cc(F)ccc1-c1ccc(CN2CCOC(C(N)=O)C2)o1 +CC(C1CC1)N(C)Cc1nc2ccccc2c(=O)[nH]1 +CC1CN(C(=O)C2(c3ccc(Cl)cc3)CCC2)CC(C)O1 +Clc1ccc2c(c1Cl)CCNC2c1ccncc1 +O=C(NCc1cccnc1)c1ccc2cc[nH]c2n1 +CC(C)NC(=O)CCN1CCCc2c(N)cccc21 +COc1ccc2nc(NS(=O)(=O)Cc3ccccc3)sc2c1 +CC(C)Cc1noc(C2CC(=O)Nc3ccccc32)n1 +Cc1ccc(S(=O)(=O)NCCNC(=O)c2ccccc2C)cc1 +COc1ccc(C2(Cc3ccccc3C)NC(N)=NC2=O)cc1 +Cc1noc2nc(-c3ccc(F)cc3)cc(C(=O)NCCCO)c12 +CCC1CCCCN1S(=O)(=O)c1ccc(N)nc1 +CNC(=O)CN1CCN(C(=O)C2(c3ccc(Cl)cc3)CCC2)CC1 +CN(CC1CCCCC1)C(=O)CSc1nncn1C +CCOc1ccc(F)c(C(=O)Nc2cc(OC)ccc2O)c1F +O=C(NCCCO)c1ccccc1SCc1cn2ccccc2n1 +CC(C)C(=O)NCCNC(=O)c1csc(-c2ncccn2)n1 +CCn1ncc(-c2ccc3c(c2)OCCO3)c(N)c1=O +COCCNC(=O)NC(C)c1ccc(OC)cc1OC +CCCCS(=O)(=O)N1CCCC(C(=O)Oc2ccccc2)C1 +C=CCCCN(C)C(=O)c1c(O)cc(F)cc1F +CC(NC(=O)OC(C)(C)C)C1CCCCN1C(=O)c1ccnnc1 +Cn1cc(NC(=O)Cn2ccc3ccc(Cl)cc32)cn1 +CC(C)N(CCCO)C(=O)c1cc(C2CC2)on1 +CC(=O)N1CCN(C(=O)c2nccc3c(N)ccc(F)c23)CC1 +O=C1NC(C=Cc2ccco2)Nc2ccc(Cl)cc21 +Cc1ccc(CNC(=O)CCC(=O)N2CCOc3ccccc32)s1 +CCS(=O)(=O)NCCNc1ccc(Br)cc1C#N +Cc1n[nH]c(C)c1NC(=O)COc1cccc(C(F)(F)F)c1 +CC(=O)NCc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1 +O=c1[nH]nc(CCn2ccnc2-c2ccccc2-c2ccco2)[nH]1 +c1ccc(CNCCc2nc3c(s2)CCCC3)nc1 +Cc1ccccc1C(C)NC(=O)Cc1csc(N2CCCC2=O)n1 +COc1ccccc1N1CCC(CNC(=O)N(C)C(C)C)C1 +O=C(CS(=O)(=O)c1ccccc1Br)NC1CC1 +OC(COc1ccccc1)Cn1cc(Br)cn1 +CCOC(=O)c1sc(NCc2ccccc2OC)nc1C +CC(=O)Nc1ccc(Cl)c(NC(=O)NC(C)c2cc(C)oc2C)c1 +CCC(CC)c1nn2c(C#N)c(C(C)C)nc2s1 +CCC(=O)c1ccc(S(=O)(=O)N2CCN(CC)CC2)cc1 +Cc1ccc(NCC(=O)N2CC(C)OC(C)C2)cc1Br +CC(C)CC(=O)Nc1ccc(OCC(F)(F)F)c(C#N)c1 +N#Cc1ccc(NC(=O)C2CN(Cc3ccccc3)CCO2)cc1 +O=C(Nc1ccc(Oc2ccncc2)cc1)C1CCC1 +O=C(Nc1ccccc1Cl)c1nc(-n2ccnc2)ncc1Cl +COc1cccc(CN2C(=O)OCC2C(=O)NCCC(N)=O)c1 +O=C(Cc1c[nH]c2ccccc12)NCCc1ccncc1 +COC(C)C(=O)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +Cc1cc2ncn(-c3nnnn3-c3ccccc3)c2cc1C +CN(C)C(=O)CSc1nnc(-c2ccc(C(C)(C)C)cc2)n1N +CS(=O)(=O)N1CCC(C(=O)Nc2ccncc2)CC1 +O=C(CCCNC(=O)C1CC1)Nc1c[nH]cc(Br)c1=O +O=C(NCc1cccnc1)c1cc2occc2n1-c1ccccc1 +O=C(NCCNC(=O)c1cccnc1)Nc1cc(F)ccc1Cl +Cc1ccc(S(=O)(=O)Nc2cccc(C(=O)N(C)CCO)c2)cc1 +CCc1sc(C(=O)NCC(C)(C)N2CCOCC2)cc1C +CCOC(=O)C1CCN(S(=O)(=O)NCc2cccc(C)c2)CC1 +O=C(Cc1cc(-c2ccccc2)on1)NCc1ccc(F)cc1 +Cc1cc(NC(=O)c2cnccn2)ccc1NC(=O)c1cccs1 +Cc1cc(=O)[nH]c(SCC(=O)N2CCc3ccccc3C2)n1 +CCCCNC(=O)c1ccnc(-c2cccs2)c1 +CN(Cc1cnccn1)Cc1ccc2cc(Cl)ccc2n1 +CC(NC(=O)c1cccs1)C(=O)Oc1ccc(C#N)cc1Cl +Cc1cc(C)c(S(=O)(=O)NCCNC(=O)c2ccccc2)c(C)c1 +Cc1ccc2nc(C3CCCN3C(=O)c3ccc(=O)n(C)c3)[nH]c2c1 +CCCCN(C)S(=O)(=O)N1CCN(c2cc(C#N)ccn2)CC1 +c1cncc(C(c2nc(C3CC3)n[nH]2)N2CCOCC2)c1 +COc1ccc(C)cc1NS(=O)(=O)c1ccc(C(C)=O)cc1 +CN(C)S(=O)(=O)N1CCC(C(=O)NCC2CCCO2)CC1 +O=C(C1CCCN1C(=O)Oc1ccccc1)N1CCCCC1 +Cc1c(C(=O)NCc2ccncc2)nnn1-c1cccc2ncccc12 +Cc1ccc(-n2nc3c(c2-n2cccc2)CN(C(=O)C2CC2)C3)cc1 +COCc1nnc(NC(=O)Cc2nn(C)c(=O)c3ccccc23)s1 +CC1CN(C(=O)c2cc(-c3ccco3)on2)C(C)CO1 +Nc1nc2cccc(N3CCN(c4cccc(Cl)c4)CC3)n2n1 +COc1cccc(C2CCN2C(=O)c2cc(CC(C)C)n[nH]2)c1 +Cc1ccncc1NC(=O)N1CCOCC1C1CC1 +CCNc1ccc(-c2cccc(C(C)OC)c2)nn1 +CN(C(=O)Cc1ccc(-n2cccn2)cc1)c1cccc2ncccc12 +CC(=O)Nc1ccc(NC(=O)C(C)Oc2ccc(F)cc2)cc1 +C#CCN1CCN(C(=O)NCC(C)CC(=O)OCC)CC1 +Cc1cc(C)n(-c2ncnc(Nc3ccc(Cl)cn3)c2N)n1 +CCOc1ccccc1NC(=O)COc1ccc2c(c1)OCO2 +CCN(CC1CC1)C(=O)NCc1cn(-c2ccccc2)nn1 +Cc1nnc(Sc2ccc(NC(=O)c3occc3C)c(C)c2)s1 +CNC(=O)c1ccc(OC)c(NC(=O)NCc2cccc(C)c2)c1 +COC(=O)c1ccc(NCc2cccnc2)cc1O +Cc1ccc(S(=O)(=O)C(C)C(=O)Nc2ccc(C)cc2C)cc1 +COc1cc2c(cc1O)C(c1ncccn1)NCC2 +O=C(C1CCCC1)N1CCCC(S(=O)(=O)NCC2CC2)C1 +CC(C)(CO)CCCNC(=O)N1CCC(CN2CCOCC2)CC1 +Cc1ccccc1OCC(=O)NCCC(O)c1cc2ccccc2o1 +c1ccc2c(SCCN3CCOCC3)cccc2c1 +Cc1ccc(SCC(=O)Nc2ccccc2-n2cnnn2)cc1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)NCC3CCC3)ccc21 +CCCCN(C)C(=O)C(C)n1nc(CC)n2c(cc3occc32)c1=O +O=C(CCc1ccco1)N(Cc1ccccc1F)C1CC1 +CCC1CCCCC1NC(=O)Nc1cnn(C)c1 +CCCCCC(=O)OCC(=O)N1CCCCCC1 +CCS(=O)(=O)N1CCC2(Cc3ccccc3NC2=O)C1 +Cc1cccc(CCC(=O)Oc2cccc(C(=O)N(C)C)c2)c1 +CCOC(=O)c1sc2nc(C)nc(NCc3ccco3)c2c1C +CSc1cc(C(=O)OCc2nc(-c3ccccc3)no2)ccn1 +COC(=O)c1ccc2[nH]cc(-c3csc(-c4cnccn4)n3)c2c1 +CCN1CCN(S(=O)(=O)c2cccc(C#N)c2)CC1 +O=C1COc2cc(NC(=O)NCc3ccncc3)ccc2N1 +CC(C)Cc1ccc(-c2cc(CO)nn2CCCO)cc1 +CC(C)(C)c1ccc(O)c(NC(=O)CNC(=O)C2CC2)c1 +CC(=O)Nc1ccc(Cl)c(-c2nc3ccccc3o2)c1 +CC(=O)c1ccc(C(=O)Nc2nc(-c3ccc(C#N)cc3)cs2)cc1 +CC1C(=O)Nc2ccc(S(=O)(=O)N3CCCCC3)cc2NC1=O +COC(=O)C1CCCCCC1NC(=O)c1ccncc1Cl +CCc1noc(C(C)N2CCN(CC(=O)N3CCCC(C)C3)CC2)n1 +O=C(NC1CCN(c2c(F)cccc2F)C1)c1csnn1 +CCc1nc(CNCCc2cn3ccccc3n2)cs1 +CCn1nc(C)cc1C(=O)N1CCC(C)CC1c1ccco1 +CC(C)CCOC(C)C(=O)Nc1ccc(N(C)C)cn1 +Cc1cc(NC(=O)C2CCC(=O)N2)c2ncccc2c1 +Cc1ccc(CCC(=O)Nc2ccc3[nH]c(C4CCCO4)nc3c2)o1 +CN(CCNC(=O)c1ccc2c(c1)COCO2)c1ccccc1 +CC(C)c1ccc(OCCNC(=O)c2cccnc2)cc1 +CCCN(CC(F)(F)F)c1ncc(C(C)=O)s1 +CCN1C(=O)c2ccccc2NC1c1cccc(OC(C)C)c1 +O=S(=O)(c1ccc(O)cc1)N1CCc2ccccc2C1 +Cc1cc(F)ccc1NC(=O)CSc1ccccn1 +O=C(CNc1cc(Cl)c(Cl)cc1Cl)N1CCOCC1 +Cc1nc2ccccc2n1CCNC(=O)NCc1cscn1 +COc1cc(C)c(CN(C)Cc2nc3c(s2)CCCC3)cc1OC +Cc1ccc(C(=O)COC(=O)c2cc(C)n(C3CC3)c2C)s1 +c1ccc2nc(NCCOC3CCCC3)cnc2c1 +CN(C)C(=O)CN1CCN(c2ccc(F)c(F)c2)C1=O +Cc1c(-c2ccc(F)c(F)c2)ccc2nc(N)nn12 +COc1cc(C)ccc1OCC(=O)NC(C)c1ccccc1OC +Cc1ccc(C)c(CC(=O)NCc2cnc(C)s2)c1 +CC1CCCC(CO)(NC(=O)c2n[nH]cc2N)C1 +O=S(=O)(Nc1ccc(F)cc1)c1cc(-c2ccno2)cs1 +CCCOCC1CCN(C(=O)Nc2cccc3cn[nH]c23)C1 +CNC(=O)NCC(=O)NCCn1c(C)nc2ccccc21 +NC(=O)COC(=O)c1ccccc1-c1ccccc1 +CC1CCN(C2=C(C(N)=O)S(=O)(=O)c3ccccc32)CC1 +COc1cccc(NC(=O)c2cccnc2OCC(F)F)c1 +COc1cccc(-c2nn(-c3ccc(F)cc3)cc2C(=O)N(C)C)c1 +CCCOc1ccccc1C(=O)Nc1ccc(C(=O)NC)cc1 +CCN(C)S(=O)(=O)NCC(O)c1cc2ccccc2s1 +O=C(c1ccn(-c2ccccc2)n1)N1CCC2(CC1)OCCO2 +Fc1cc2c(c(Cn3cnc(-c4ccccc4)n3)c1)OCOC2 +COC(=O)CC(C)NC(=O)c1cccc(OC(F)F)c1 +COc1ncccc1CNC(=O)N(C)C(C)c1ccccc1F +CCOC(=O)C1CCCN(Cc2nc3ccc(Cl)cc3c(=O)[nH]2)C1 +CCc1onc(C)c1NC(=O)c1sccc1SC(F)F +CC(CCCO)NC(=O)Nc1ccccc1N1CC(C)OC(C)C1 +CCN(CCO)C(=O)COc1ccc(-c2ccccc2)cc1Cl +COc1ncc(NCc2c(F)cccc2F)cc1C(N)=O +NC(=O)c1ccc(COC(=O)c2ccc(OC(F)(F)F)cc2)cc1 +N#Cc1ccc(CNc2cccc(C(=O)N3CCCC3)c2)c(F)c1 +O=C1CN=C(c2ccccn2)c2cc(Cl)ccc2N1CCO +COc1ccccc1NC(=O)c1cccn2nccc12 +CC(=O)NCC1CCN(C(=O)c2ccccc2C)CC1 +O=C(Nc1ccc(-c2cn3ccsc3n2)cc1)C1CCCO1 +Cc1nc(NC(=O)c2scnc2C2CC2)cc(C2CC2)n1 +O=C(Nc1ccnn1Cc1ccsc1)C1CC2C=CC1C2 +COCc1ccc(C(=O)N2CCCC2c2ccc3c(c2)OCCO3)o1 +CC1(C)COCCN1CCNS(=O)(=O)c1ccc(F)cc1F +Cc1nc(-c2cccc(NC(=O)N3CCOCC3C3CC3)c2)oc1C +CC(N)C(=O)OCc1ccc2c(c1)CCCS2(=O)=O +COc1ccc(C(=O)N2CCCn3c2nc2ccccc2c3=O)cc1 +Cc1ccc(-n2nnnc2CNS(=O)(=O)c2ccccc2F)cc1 +CCCCn1c(=O)c2sccc2n(CC(=O)NC(C)C)c1=O +CCOc1ccc(C(=O)CCC(=O)OC)c2ccccc12 +CCC(C)OC1OC(CO)C(O)C(O)C1NC(C)=O +COc1ccc2nc3c(c(C#N)c2c1)CN(C)CC3 +CSc1nc2ncn(CC(=O)N(C)C3CC3)c(=O)c2s1 +Cc1nnc2n1CCN(CC(=O)N1CCCC3CCCCC31)C2 +CCCOc1c(Cl)cc(C(=O)N(C)C(C)C)cc1OCC +O=C(Nc1cccc(N2CCCS2(=O)=O)c1)NC1CC1 +COc1ccccc1C(=O)NC1(C#N)CCOCC1 +CC(NC(=O)c1ccc(=O)n(C)c1)c1ccc(F)c(Cl)c1 +CCN(CCC#N)C(=O)Nc1cccn(Cc2ccccc2)c1=O +Cc1cc(NC(=O)c2cccc(C(F)(F)F)c2)cc(C)n1 +O=C1CCC(C(=O)Nc2nc3c(s2)C(=O)NCCC3)N1 +Cc1cc(Cl)ccc1NC(=O)c1c(C)n[nH]c1N +O=C(NCCNC(=O)c1ccc(O)cc1)Nc1ccc2c(c1)CCC2 +CCNC(=O)CSc1nnc(-c2c[nH]c3ccccc23)o1 +CNc1nc(CNC(=O)Nc2cccc(-c3ncc(C)o3)c2)cs1 +COc1ccc(-c2csc(C(C#N)C(=O)c3ccsc3)n2)cc1 +Cc1ccc(NC(=O)C2CCN(C(=O)CCC(C)(C)C)CC2)nc1 +CS(=O)(=O)NC1(C(=O)NC2CCCCC2)CCCCC1 +Cc1cc(C)n2cc(CN3CCOC(C)C3)nc2n1 +O=C(NCCc1cccnc1)C1CCN(c2ccc(Cl)cc2)C1=O +O=C(Nc1ccccc1)C1CCN(C(=O)C2CC2)CC1 +Cc1cccc(C(C)C)c1NC(=O)NCc1cccc(C(N)=O)c1 +CC(C)c1nnc(CN2CCn3c(nnc3C(C)C)C2)o1 +COC(=O)CCN(C(=O)C1COc2ccc(F)cc2C1)C(C)C +CCc1cc(=O)[nH]c(-c2ccc(F)c(Cl)c2)n1 +O=C(NC1CCc2[nH]ncc2C1)c1cn(-c2ccccc2)nn1 +Cc1oncc1C(=O)N1CCC2(CCN(Cc3ccccn3)C2=O)C1 +Cc1ccc(-c2csc3ncn(CCn4cccn4)c(=O)c23)cc1 +O=C(NCC#CCOc1cccnc1)c1cccc2ccccc12 +CSc1cccc(N(C)C(=O)c2cccnc2OCC(F)F)c1 +O=C(Cc1ccc2c(c1)OCC2)NCCc1ccco1 +O=C1N(c2ccccc2)Cc2nc(=O)n(Cc3ccccc3)n21 +CCCn1c(=O)c2c(nc(-n3nc(C)c(C)c3C)n2CC)n(C)c1=O +O=C(c1ccc(-c2nc3ccccc3o2)cc1)N1CCOCC1 +NC(=O)c1ccc(C(=O)NCc2ccccc2Cn2cccn2)cc1 +COC(=O)NCC(=O)NCc1ccc(C)cc1C +CC1CC(O)c2ncnc(N3CCN(C(=O)OC(C)(C)C)CC3)c21 +COc1cccc(CC(=O)Nc2ncc(C#N)s2)c1 +Cc1cc(NC(=O)N(C)Cc2ccccc2)n(Cc2ccccc2)n1 +COCCNC(=O)C(CC(C)C)N1CCCCC1=O +Cc1nc(C)n(-c2ccccc2NC(=O)NCC2(C)CCC2)n1 +CCCC1CN(C(=O)c2ccc(C)c(OC)c2)CCO1 +N#Cc1cc(S(=O)(=O)NCC2CCCO2)ccc1F +CCc1onc(C)c1NC(=O)NC(C)c1nc2ccccc2[nH]1 +O=C(NCCNC(=O)N1CCOCC1C1CC1)c1cccs1 +CCOC(C)C(=O)Nc1sc2c(c1C#N)-c1ccccc1CC2 +CCc1nc(CN2CCN(C(=O)Cc3ccc[nH]3)CC2)cs1 +COc1ccc(-n2cnnn2)c(NC(=O)c2n[nH]c3c2CCC3)c1 +COc1cccc(CCCNC(=O)NC(C)c2c(C)noc2C)c1 +COCCOc1ccc(NC(=O)C2CC2C)cc1F +COc1ccc(C#N)cc1CN(C)S(=O)(=O)c1cccs1 +CC(C)(C)C(=O)NCCCC(=O)N1CCC2(CC1)OCCO2 +CCn1cc(C2C(C(N)=O)=C(C)Nc3nc(SC)nn32)cn1 +Cn1ccnc(NC(=O)c2cc(-n3cccn3)ccn2)c1=O +Brc1c(OCc2nccs2)ccc2ncccc12 +Cc1ccc(C)c(S(=O)(=O)N(CCC#N)CCC#N)c1 +Cc1ccc(Sc2ncccc2C(=O)NCc2ccccn2)cc1C +Cc1csc2ncc(C(=O)NCCN3CCOCC3)c(=O)n12 +COc1ncccc1NS(=O)(=O)c1c(C)cc(NC(C)=O)cc1C +CN(CCOc1cccc(F)c1)S(=O)(=O)c1c[nH]c2ncccc12 +Cc1cc(C(=O)NCCC2CN(C)CCO2)c2cccc(C)c2n1 +COc1cc(OC)cc(C(=O)NC(C)c2ccc(F)cc2F)c1 +CCc1noc(C(C)Sc2cccc(OC)c2)n1 +CCn1c(=O)n(CC(=O)NC(C)c2cccnc2)c2ccccc21 +N#CC(NCc1ccc2c(c1)OCO2)c1cccnc1 +Cc1cc(-n2c(C)cc(C(=O)N(C)C(C)C3CC3)c2C)no1 +COCC(=O)N1CCCC1c1cccc(Nc2nccs2)n1 +CC(=O)NC(C)(C)c1noc(-c2cccc(Oc3ccccc3)c2)n1 +COc1c(C(=O)N2CCCCC2)nnn1Cc1ccccc1Cl +COCC(=O)Nc1cc(S(=O)(=O)N(C)C)ccc1OC +CC(C)(O)CN1CCN(C(=O)c2ccc3c(c2)OCC(=O)N3)CC1 +N#Cc1ccccc1C(=O)N1CC2CCC1CN(c1ncccn1)C2 +COC(=O)c1ccc(Cl)c(S(=O)(=O)Nc2ccccc2)c1 +O=C(OCc1ccccc1)N1CCC(N2CCCC2=O)CC1 +CCn1nnnc1COc1cccc(C(=O)Nc2cnn(C)c2)c1 +COc1ccc(CN(C)C(=O)CN2C(C)COCC2C)cc1F +CSc1sc(NC(=O)c2cccnc2OCC(F)F)nc1C +CC(CCc1ccccc1)N1C(=O)c2ccccc2C1O +Cc1cccc(C(=O)Nc2cccc(Oc3ccc(C#N)cn3)c2)n1 +NC(=O)c1cccc(COC(=O)Cc2c(F)cccc2F)c1 +COC(CNS(=O)(=O)c1cccc(C)c1)c1ccc(C)s1 +CNC(=O)CSc1nnc(-c2cccs2)n1C1CC1 +Cc1ccc(-c2ccc(C(=O)NCCc3ccco3)c(=O)[nH]2)cc1 +Cc1ccc2[nH]c(=O)c(-c3ccccc3N)nc2c1 +CCC1CN(C(=O)C2COCCN2C(C)=O)CCN1CC(F)F +Cc1noc(-c2cccnc2NCCCNC(=O)C2CCC2)n1 +Cc1cc(C(=O)N2CCCC(C(=O)c3ccc4ccccc4c3)C2)no1 +CN(C(=O)c1cccc(F)c1)C(C#N)c1ccccc1 +CN(C(=O)c1ccc2c(c1)CCO2)c1ccc(F)c(F)c1 +Cc1noc(C2COCCN2Cc2nc(C(F)(F)F)cs2)n1 +COc1ccccc1C(C)N(C)C(=O)NCC1CC1 +CC(C)CNc1nc(C(=O)Nc2ccc3c(c2)OCO3)cs1 +O=C(c1nc2ccccc2s1)N(Cc1ccsc1)C1CC1 +Cc1noc(C)c1CN(C)C(=O)c1ccc(-c2cc[nH]n2)cc1 +Cc1noc(C)c1C(=O)N(C)C(c1ccccc1)c1ccccn1 +NC(=O)c1cc(NC(=O)CCc2cccs2)cc(C(N)=O)c1 +CC(=O)NCCNC(=O)Nc1cccc(Cl)c1Cl +NC(=O)NCCC(=O)NC1CCCN(c2ccccc2F)C1=O +Cc1nn(C)c(C)c1CC(=O)N(CCC#N)CCC(F)(F)F +Nc1ccccc1C(=O)Nc1c(F)cc(F)cc1Br +O=C(NCc1nc(C2CC2)no1)NC(C1CC1)C1CC1 +O=C(NCCOc1cccnc1)c1cnn(-c2cccc(Cl)c2)c1 +Cc1ccc(SCC(=O)NC(C)CCN2CCOCC2)cc1 +Cc1cnc(C(=O)Nc2ccccc2C(F)(F)F)cn1 +Cc1ccc(C)c(NCc2nc(-c3ccco3)no2)c1 +CCc1onc(C)c1NC(=O)N(Cc1ccccc1)C1CC1 +CCc1nn2c(=O)cc(CSc3n[nH]c(N)n3)nc2s1 +COC(C)(C)c1noc(-c2nc(SC)n3ccccc23)n1 +Cc1cc(C)c(NC(=O)CCc2nc(-c3ccsc3)no2)c(C)c1 +Cc1ccc(S(=O)(=O)N(CC(N)=O)C2CCCC2)c2cccnc12 +COc1ccc(-c2cn3c4ccccc4nc3n2CCO)cc1OC +CNC(=O)c1ccc(Cl)cc1NCc1nccn1C(F)F +COCCCNC(=O)CC1Oc2ccccc2NC1=O +COC(=O)Cn1nc2c(Sc3cccc(F)c3)nccn2c1=O +Cc1ccc(Cn2nnc(C(=O)Nc3ccc(F)c(F)c3)c2N)cc1 +CN(C(=O)Cn1c(=O)oc2ccccc21)c1ccc2ccccc2c1 +O=C(Cc1ccc(-n2cnnn2)cc1)NC1CCCCCC1 +CNC(=O)c1sc(Cc2nnc3n2CCCCC3)nc1C +CCOCCOC(=O)Cn1c(C)nc2c(N)cccc21 +Cc1ccc(C)c(C(=O)N2CCN(C(=O)C(C)C)CC2)c1 +Cn1nccc1CN1CCCCC1c1nc(-c2ccccc2)no1 +CC1CC1c1ccc(CN(C)S(=O)(=O)c2cnn(C)c2)o1 +CCCCc1cc(NC(=O)c2cc(C(C)=O)c[nH]2)[nH]n1 +CC(C)Oc1cccc(C(=O)N2Cc3cnc(C(C)(C)C)nc3C2)c1 +CC1C(=O)NCCN1C(=O)c1cccc(Oc2ccccc2)c1 +Cn1nc(C(=O)N2CCC(O)(CO)CC2)c2ccccc21 +COC(C)c1nc(C)c(C(=O)NCc2cc3ccccc3o2)s1 +O=C(C1CCOC1)N1CCC2(CCc3ccccc32)CC1 +COc1ccccc1CNC(=O)c1nc2ccccc2s1 +COC(=O)c1cc(CN2CCOC(c3cccc(O)c3)C2)c[nH]1 +CC(C)(C)c1nnc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)s1 +COc1ccc(Nc2nc(NCCO)nc3[nH]ncc23)cc1 +Cc1noc(CCCC(=O)N2CCNC(=O)C2)n1 +Cc1ccc2c(N)c(C(=O)N3CCC(C)CC3)sc2n1 +CN1C(=O)CCOc2ccc(C(O)C(=O)NC3CC3)cc21 +CCOC(=O)N1CCC(NC(=O)c2cc3ccccc3[nH]2)CC1 +CSc1ccccc1NC(=O)NC(C)C(=O)NCc1ccccc1 +Cc1noc(CNCC(O)c2c(F)cccc2F)n1 +O=S(=O)(N=c1ccc(-c2ccccc2)c[nH]1)c1cccnc1 +COC(=O)c1cccc2ccn(C(=O)OC(C)(C)C)c12 +COC(=O)CCCn1nnc(-c2cccc(OC)c2)n1 +CCCN(Cc1cnc(C2CC2)s1)CC1CCCCO1 +COCCNC(=O)c1ccc(-c2ccccn2)nc1N +Cc1c(C(C)NC(=O)NCc2ccncc2)oc2ccc(F)cc12 +CN(CCOc1ccc(Cl)cc1)C(=O)NCc1ncn(C)n1 +COc1ccc(NC(=O)CCCSc2ccccc2)cn1 +Cn1nccc1C(=O)NC(C)(C)c1nc2c(c(C(N)=O)n1)OCCO2 +COC(CNC(=O)CC(C)C)c1cccc(F)c1 +CC(=O)NCC(=O)NC(c1ccc(C(C)(C)C)cc1)C(C)C +COC(=O)C1CCCCN1S(=O)(=O)c1ccc(F)cc1C +CCN(C(=O)Cn1c(=O)c2c(ncn2C)n(C)c1=O)C1CCCCC1 +CC(NC(=O)c1ccnc(N)c1)c1cccc(Br)c1 +CC1(C)C(NC(=O)NCc2cc(=O)[nH]c3ccccc23)C2CCOC21 +CC1(C)CN(Cc2ncc(-c3ccc(F)cc3)o2)CCO1 +Cc1ccc(NC(=O)NCC(=O)OC(C)C)c(C)c1 +Oc1c(F)ccc2c1CCNC2C1CCOCC1 +CNC(=O)NCc1cccc(C(=O)N2CCCCC2)c1 +CCC(C)NC(=O)CSc1ncnc2c(-c3ccccc3)c[nH]c12 +COc1ccc(C(=O)COC(=O)c2cc(C)ccc2C)cc1OC +Cc1cc(C)n(-c2ccc(COC(=O)C3CCC3)cc2)n1 +CC(C)(C)n1nnnc1C(c1ccccc1)N1CCOCC1 +COc1cccc(C(=O)OC2CCCC(OC)C2)c1OC +CCN(C(=O)COc1ccc(C#N)cc1Cl)C1CC1 +N#Cc1nnn(-c2nccs2)c1-c1ccc2c(c1)OCO2 +O=C(CCc1nnc(-c2ccsc2)o1)N1CCCCCC1 +Nc1ccc2c(c1)CN(C(=O)CCc1ccccc1)CC2 +Cn1ncc2c(=O)n(CC(=O)NCC(C)(C)c3cccs3)cnc21 +C=CCNC(=O)NC(C)c1cccc(N2CCCC2=O)c1 +Fc1ccccc1-c1cc(NCCn2cnnc2)n2nccc2n1 +O=C(Nc1cccnc1F)N1CCC2(CC1)CC(O)CO2 +CC(=O)NCCCNC(=O)Nc1cccc(C#N)c1 +N#CC(Cc1c[nH]c2ccccc12)C(=O)NCc1ccccc1 +CCc1ccc(C2COCCN2Cc2ncccc2C(F)(F)F)o1 +Cc1cc2n(n1)CCC(=O)N2CC(=O)Nc1ccccc1Cl +NC(=O)c1c(NC(=O)c2cc(Cl)ccn2)sc2c1CCC2 +Cc1nc(C2(NC(=O)c3cc(C4CC4)on3)CCCCCC2)no1 +Cc1ccc2occ(CC(=O)Nc3nc(C)cs3)c2c1 +CN(C)C(=O)CNC(=O)CCn1ncc2c(Cl)cccc21 +O=C(c1c[nH]nc1C1CCCCC1)N1CCC2(CC1)OCCCC2O +COc1ccc(OC)c(NC(=O)C2(n3cnnn3)CCCCC2)c1 +CC(C)c1nnc2n1CC(NC(=O)c1ccc3cc[nH]c3c1)CC2 +NC(=O)c1cccc(OC(=O)Cc2ccc(-n3cnnn3)cc2)c1 +CS(=O)(=O)N1CCN(C(=O)COc2ccc3c(c2)CCC3)CC1 +COc1cccc(CNC(=O)COC(=O)c2cccc(C#N)c2)c1 +O=C(Nc1ccc(F)c(Cl)c1)c1cc2ccccn2n1 +COC(=O)C(C)Sc1nc(-c2ccc(C)cc2)n[nH]1 +O=C(OCC(=O)N1CCOCC1)c1ccc2c(c1)OCO2 +O=C1NCCNC1Cc1cccc(-c2ccccc2)c1 +CCNC(=O)COc1cccc(NC(=O)NC(C)c2ccncc2)c1 +CNS(=O)(=O)c1ccc(-n2cc(Cl)cn2)c(N)c1 +Cc1ccccc1-n1c(SCCCC#N)nnc1N1CCOCC1 +Fc1cncc(C2NCCc3cc(F)c(Cl)cc32)c1 +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)Oc1cccc(F)c1 +Cc1cnc(NC(=O)c2ccnc3ccccc23)s1 +COc1cc(C)c(NC(=O)c2ccc(=O)[nH]c2)cc1OC +COc1ccccc1OC(=O)c1ccc(-n2cnc3ccccc32)nc1 +CCCn1c(C)nnc1SCc1noc(C(C)(C)C)n1 +CN(Cc1ccc(F)cc1)C(=O)c1cc(N)ccn1 +CC(C)(O)CCc1ccc(C(=O)NCC2(O)CCCCC2)cc1 +CCCOc1ccc(-c2cc(CO)nn2CC)cc1 +C=CCNC(=O)N1CCN(C(=O)c2cccc(Cl)c2Cl)CC1 +COCCOc1ccccc1CNC(=O)Nn1cnc2ccccc21 +CC(C)c1noc(C2CCN(S(=O)(=O)c3cccs3)CC2)n1 +COc1cnn(-c2ccc(C)cc2)c(=O)c1Cl +CCc1ccccc1NC(=O)CN(C)C(=O)COC +Cc1cc(NC(=O)c2ccc(F)cc2)n(-c2ccccn2)n1 +CCOC(C)C(=O)Nc1nc2cc(F)c(F)cc2s1 +COc1ccc2c(c1)OCC(C(=O)Nc1nnc(C(F)F)s1)C2 +COc1ccccc1C(=O)NCC(=O)Nc1ccc2c(c1)CCC2 +Cc1ccc(C(=O)N2CCN(C(=O)C(C)NC(N)=O)CC2)cc1 +CCN(CC)C(=O)CCC(=O)Nc1ccc(C)cc1Cl +CC(C)(C)NC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1 +COCCN(Cc1cccs1)C(=O)c1cccc(C#N)c1 +Cc1ccc(C(=O)N(C)CC23CC4CC(CC(C4)C2)C3)c(=O)[nH]1 +COC(=O)C(C)S(=O)(=O)Nc1cc(Cl)ccc1N +CCOc1ccc(CC(=O)Nc2cc(C)nn2C)cc1 +CCc1noc(CC)c1CNC(=O)c1cc(F)c(F)c(F)c1F +Cc1cccc(OCCCCn2nnc(CO)c2C)c1 +CC(c1cccs1)N(C)C(=O)NC1CCCN(S(C)(=O)=O)C1 +COCC(=O)NC1CCc2c(ccc(=O)n2Cc2ccncc2)C1 +COc1ccc(NC(=O)Cn2ccc(=O)c3cccc(F)c32)cc1 +COc1cccc(C(=O)Nc2c(C)ccc(N)c2C)c1 +O=C(Nc1cccc2c1CCCN2)c1cccc(O)c1 +C#Cc1cccc(NC(=O)c2cc(S(=O)(=O)NCCOC)c[nH]2)c1 +Cc1cncnc1C1CCCCN1S(C)(=O)=O +CCn1nc(C)c(Cl)c1C(=O)Nc1cccc(F)c1 +CC(NC(=O)c1ccoc1)C(=O)NCCNC(=O)C1CC1 +O=C(Nc1ccc(NC(=O)N2CCCCCC2)cc1)C1CCOC1 +COCc1cc(C(=O)N(C)C(C)c2ccc3ccccc3c2)no1 +COC(=O)C1=C(C)Nc2ncnn2C1C=Cc1ccccc1 +CC(COc1cccc(F)c1)NC(=O)c1ccc2nncn2c1 +COc1ccc(C(=O)CCC(=O)OC(C)C)cc1C +NC(=O)C1(c2nc(-c3ccncc3)nn2CCc2ccccc2)CC1 +Cc1ccc(CN(C)C(=O)CCc2ccc(F)c(F)c2)o1 +O=C(CCOc1cccc(Cl)c1)Nc1ccc2c(c1)OCC(=O)N2 +Cc1ccc(S(=O)(=O)NC(C)c2ccc(-n3cncn3)cc2)cc1 +COc1ccc(OCC(=O)Oc2ccc(C)cc2)cc1 +CCc1nnc(NC(=O)CSc2nnc(CC)n2C(C)C)s1 +CCNC(=O)N(CC)Cc1ccc(OC)c(OC)c1 +Cc1nc(Cc2nnc(SCc3ccccc3Cl)o2)cs1 +Cc1cc(C)c(C)c(OC(=O)Cn2cnc3c(cnn3C)c2=O)c1 +O=C(C1CC1c1ccco1)N1CCCC(N2CCNC2=O)C1 +N#CC(NC(=O)c1cccc(N2CCCC2=O)c1)c1ccccc1F +C=CCn1nnnc1SCc1ccc(C#N)cc1 +CCOC(C)c1nccn1CC(=O)N(C)Cc1ccccc1C +COc1ccc(CNC(=O)C2CC=CC2)c(OC)c1OC +C=CCn1c(NC(=O)CC)c(C#N)c2nc3ccccc3nc21 +COCCCC(=O)Nc1nc2ccc(NC(C)=O)cc2s1 +CC(=O)Nc1cccc(NC(=O)C(C)Nc2ccn(C)n2)c1 +C=CCNC(=O)c1ccc(N)c(OCc2ccccc2C)c1 +CC(=O)c1sc2nc(-c3ccccc3)cn2c1C +Cc1ccc(C)c(NC(=O)Nc2cc(C)nn2C)c1 +COc1ccc(NC(=O)NCc2ccccc2OC)cc1C +N#CCn1cc(S(=O)(=O)N2CCCCC2)ccc1=O +COc1ccc(NC(=O)c2ccc(F)c(F)c2)cc1N +CC(NC(=O)NCCc1cccc(F)c1)c1ccncc1 +CC1CCCCC1NC(=O)c1ccc(C(N)=O)nc1 +COc1ccc(NC(=O)C(C)n2cnc3ccccc3c2=O)cn1 +CC(C)Nc1ncc(Br)c2c(N)ccc(F)c12 +CCN(C(=O)COc1cc(C)cc(C)c1C)C1CC1 +COc1cc(OC)cc(C(=O)Nc2cc(CO)ccn2)c1 +Cc1cc(=O)c(C(=O)Nc2c(-c3ccccc3)ncn2C2CC2)c[nH]1 +Cc1nc[nH]c1C(=O)N1CCN(C)C2(CCNC(=O)CC2)C1 +CC1=NC(=O)C(CC(=O)NCc2ccc(C)cc2)C(C)=N1 +CCCn1nccc1C(=O)NCCc1ccc(O)cc1 +COc1ccc(Br)cc1C(CC(N)=O)C1CC1 +c1cc(-c2nc(-c3cn4ccccc4n3)no2)cc(-n2cnnc2)c1 +Cc1c(CNCC(C)c2nc(-c3ccccc3)no2)cc(C#N)n1C +N#CCc1ccc(-n2nc(C#N)c3c2CCNC3)cc1 +Cc1cccc(NC(=O)CN2CCN(C(=O)C3CCCO3)CC2)c1C +Cc1cccc(C(C)C)c1Nc1ncccc1C(N)=O +CCn1c(CSc2nccn2C)nc2c(F)cccc21 +CCOC(=O)c1c(-c2ccccc2)nc2sccn12 +Cc1c(N)cc(Cl)c2c1NC(=O)C(c1ccc(F)cc1)O2 +CCn1c(-c2ccc(OC)c(Cl)c2)ccc(CC#N)c1=O +CCCCNC(=O)c1cnc(N2CCOCC2)nc1COC +O=C(NC1CC1)c1ccnc(C=Cc2ccccc2)c1 +COC(=O)CCN(C)C(=O)CCn1ccccc1=O +COC(=O)c1ccccc1NC(=O)c1cc(C)no1 +CN1CCOCC1C(=O)NC(c1cccc(Cl)c1)c1ccccn1 +O=C(c1ccn(C(F)F)n1)N1CCC(c2ccncc2)CC1 +Cc1ccc(NCC2CCC=CO2)c2cccnc12 +N#Cc1c(F)cccc1NCC(O)c1cccs1 +O=C(CC1CCCO1)N1CCN(Cc2ccc3c(c2)OCCO3)CC1 +N#CC(Cc1ccccc1)C(=O)Nc1ccccc1F +CCOC(=O)C1(NC(=O)c2ccco2)CCCC1 +CCn1cc(C(=O)Nc2ccc(S(=O)(=O)NC3CC3)cc2)cn1 +COc1ccc(-c2nc(OC(C)=O)cc(=O)o2)cc1 +Cc1ccc(Oc2ccc(NC(=O)Cn3ccnn3)cn2)cc1C +COCc1ccc(C(=O)N2CCC(C(=O)N3CCCC(C)C3)CC2)o1 +COc1cccc(CCOc2ccc(CO)cc2OC)c1 +CC(C)COC(=O)c1ccc(Nc2ncnc(N(C)C)c2N)cc1 +Nc1ccc2nc(SCC(=O)c3ccc(O)cc3)sc2c1 +NC(=O)c1ccc(Cl)cc1NC(=O)c1ccccc1OC(F)F +CCCNS(=O)(=O)c1ccc(CNC(C)=O)s1 +CC(=O)c1c[nH]c(C(=O)OC(C)C(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 +COC(=O)CSc1nnc(-c2cccc(C)c2)n1C +COCc1c(CO)nnn1-c1nc(-c2ccccc2)cs1 +CC1CN(C(=O)c2ccc(-c3ccc(F)cc3)o2)C(C)CO1 +CCCn1nccc1C(=O)NCC1CCN(c2cnn(C)c(=O)c2)C1 +CN(Cc1ccccc1F)C(=O)c1cccc(F)c1 +COc1ccc(CCCCC(=O)N2CCN(C(=O)N(C)C)CC2)cc1 +Fc1cccc2c1CCNC2c1cnn2ccccc12 +CC(C(=O)Nc1cc(C(C)(C)C)nn1-c1ncccn1)n1ccnc1 +O=C(NCCCOC1CCCCC1)c1n[nH]c(=O)c2ccccc12 +Cc1cc(C(=O)N2CCN(Cc3ccc(C)c(F)c3)CC2)c(C)o1 +O=C(C1CC1)N1CCC2(C=Cc3ccc(F)cc32)CC1 +Cc1csc(NC(=O)N(C)CC2CCCC2)n1 +CC(NC(=O)NCCCNS(C)(=O)=O)c1ccc(Cl)cc1 +C#CCOC(=O)Cn1cnc2ccc(Br)cc2c1=O +CCN(CC)C(=O)CSc1nc2ccsc2c(=O)n1C +O=C(NCc1cc(-c2cccs2)on1)c1ccc2ccccc2n1 +Cc1ccc(CNC(=O)c2nc[nH]c2C(=O)NCCC(C)C)cc1 +Cc1ccccc1-c1nnc2sc(NC(=O)C(C)C)nn12 +CCSc1ccccc1C(=O)N1CCN(c2ccccc2)CC1 +CC(Sc1nc2sccc2c(=O)[nH]1)C(N)=O +CC(C)Sc1ccc(CC(=O)N2CCC(O)CC2)cc1 +Cn1ccc(C(=O)Nc2ccccc2Cc2ccccc2)n1 +COc1ccc(CN(C)C(=O)Cn2c(=O)oc3ccccc32)cc1F +CNC(=O)C1CN(C(=O)Nc2ccccc2)CC12CCCC2 +COc1c(CNc2ccc3[nH]ncc3c2)c(C)nn1C +CC(C)Oc1ccccc1NC(=O)c1cc(F)ccc1N +Cc1cc2c(c(C)c1N)N(C)C(=O)C(c1ccccc1)O2 +CCCS(=O)(=O)c1nc2ncc(C)cc2s1 +O=C(NCCCO)c1cc2ccc(Br)cc2[nH]1 +Cc1nnc(SCc2c(F)cccc2Cl)n1C +CN1C(=O)CC(C(=O)NCCCCC(C)(C)C)C1c1cccnc1 +Cc1cc(=O)n2ncnc2n1CC(O)CCc1ccccc1 +O=C(Nc1ccc(-c2ccccc2)cc1)N1CCCC1CO +COc1ccc(OC(=O)COc2ccccc2C#N)cc1 +Cc1cc(-n2c(C)cc(C(=O)CSc3nccn3C)c2C)no1 +Cc1ccc(C(=O)N2CCN(C(=O)CCNC(=O)C(C)(C)C)CC2)o1 +CS(=O)(=O)N1CCCC(c2nc(-c3ccccc3)c[nH]2)C1 +O=C(CSc1ncnc2ccccc12)NCc1ccc(F)cc1 +CCN(C(C)COC)S(=O)(=O)c1cccc(Br)c1 +CC(=O)c1cc(Br)c(N2CCCC2)[nH]1 +O=C(c1cccc(CNc2cnc3ccccc3n2)c1)N1CCCCC1 +O=C(Cc1ccc[nH]1)NCCc1cnn(-c2ccccc2)c1 +CS(=O)c1ccc(C(=O)NC(Cc2ccccc2)C2CC2)cc1 +CCN1C(=O)C(O)(CC(=O)c2cccc(OC)c2)c2ccccc21 +Cc1cc(N)c2c(Br)cnc(N3CCOCC3)c2c1 +COCc1ccccc1CNC(=O)Nc1ccc(F)c(C#N)c1 +COc1cccc(C(=O)OC(C(=O)N(C)C)c2ccccc2)c1O +COc1ccccc1CC1CCCN1C(=O)c1cn[nH]c1C +CC(=O)Nc1ccc2c(COc3ccc(F)cc3F)cc(=O)oc2c1 +CC(=O)Nc1ccc(F)c(C(=O)N2CCCCC2)c1 +C#CCNC(=O)CNC(=O)Nc1cccc(Oc2ccccc2)c1 +CC(C)C(NC(=O)c1ccccc1F)C(=O)NCC1CC1 +CC1CCCCC1NC(=O)Cn1ncc2ccccc2c1=O +CC(CO)NC(=O)C1CC(=O)N(C2CCCC2)C1 +N#CCC1Cc2cccc(Br)c2NC1=O +COc1ccc(S(=O)(=O)N(C)C)cc1C(=O)Nc1ccccc1 +CSc1ccc(-c2csc(NCC3CCCO3)n2)cc1 +CCC(C)(C)NC1C(=O)Nc2ccc(Br)cc21 +CC(NC(=O)c1cc(N2CCCC2=O)ccc1Cl)C1CCOC1 +CCCOc1cc(NCc2ccncc2)nc(C(C)C)n1 +CC1(O)CCN(C(=O)c2cccc(N3CCOCC3)c2)CC1O +COc1ccc(CCC(=O)NCC(C)C#N)cc1OC +CNC(=O)c1ccc(NC(=O)N(C)Cc2ccoc2C)c(Cl)c1 +O=C(COC(=O)CSc1nc2ccccc2o1)NC1CC1 +CC(C)CNC(=O)c1ccc(Br)cc1F +Cc1cc(C)n(CCC(=O)Nc2ccc(Cl)cc2F)n1 +N#CC(Cc1ccccn1)(c1ccccc1)c1cnccn1 +Nc1ccc(Cl)c(NC(=O)c2ccc(C(F)(F)F)cc2)c1 +Cc1nc(-c2ccc(CCNC(=O)c3cnccn3)cc2)cs1 +COc1cc(OC)c(-c2nc3ccc(C)cc3c(=O)o2)cc1OC +C=CCNS(=O)(=O)c1ccc(NC(=O)c2ccncc2)cc1 +CC=Cc1ccc(OC(=O)c2ccoc2)c(OC)c1 +CCc1nc(CCNC(=O)c2cccc(-c3ccoc3)c2)cs1 +CC(C)C(C)NC(=O)c1cc2c([nH]c1=O)CCCC2 +CC(=O)N1CCN(Cc2cccc(Oc3ccc(Cl)cc3)c2)CC1 +COc1ncccc1C(=O)N1CCCC(N(C)C(=O)OC(C)(C)C)C1 +CCC(CC)C(=O)NCC(O)c1ccc(SC)cc1 +Brc1ccccc1NCc1noc(-c2ccoc2)n1 +N#Cc1ccccc1-c1ccccc1C(=O)NC1CC1 +CC(=O)c1ccc(C)cc1OS(=O)(=O)N(C)C +Cc1ccccc1Cc1c(C)nc2n(c1=O)CCS2 +CCOc1ccc(NC(=O)Cn2c(=O)oc3ccccc32)cc1 +Cc1ccc(C(C)C)c(OC(=O)CCNC(=O)c2ccsc2)c1 +COc1cc(C(=O)NCc2cc[nH]c(=O)c2)ccc1C +Cc1nc(SC(C)C(=O)Nc2ccccc2)[nH]c(=O)c1CCO +CCN(CC)C(=O)CN(c1ccccc1)S(=O)(=O)N(C)C +OCc1cc(Br)cnc1Oc1cc(F)cc(F)c1 +O=C(Cc1cn2ccsc2n1)Nc1ccccc1N1CCCC1=O +CC1(C)CN(C(=O)c2cccc(N3CCCC3=O)c2)CC1(C)O +CC(C)C(NC(=O)CN(c1cccc(F)c1)S(C)(=O)=O)C(C)C +O=C1Nc2ccc(Cl)cc2C1NCCN1CCOCC1 +COc1ccccc1OCCN(C)C(=O)CNC(C)=O +COc1ccc(NC(C)=O)cc1NC(C)C(=O)Nc1cccc(F)c1 +Cc1cc(C(=O)NCc2ccccc2)nc(N2CCCCC2)n1 +CCc1cnc(N(C)CCc2scnc2C)nc1 +O=C(NCCNc1ccc(C(F)(F)F)cn1)C1CCOCC1 +Cc1ccc(Cn2nnc(-c3ccccc3)n2)cc1 +O=C(Cn1ccccc1=O)N(Cc1cccs1)c1ccc(F)cc1 +COCC(=O)N1CCN(C(=O)NC2CCc3c(F)cccc32)CC1 +CC(=O)N1CCCC1C(=O)NC(C)Cn1cccn1 +COc1ccc(F)c(NC(=O)NC(C)COCC(C)C)c1 +COCCCn1ccc(NC(=O)Cc2c(F)cccc2F)n1 +Cc1ccc(C(=O)N(CCO)C2CCCC2)n1C +O=C(CN1Cc2ccccc2C1=O)N1CCCCC1 +Cc1ccc2cc(CCNC(=O)C(C)C)c(=O)[nH]c2c1C +CCOC(=O)c1sc(=NC(=O)c2ccn(C)n2)n(C)c1C +N#CCCN(Cc1ccco1)C(=O)c1cccc(C#N)c1 +CCCCNC(=O)NC(CC)c1ccc(Cl)cc1 +CN(C)C(=O)CCSc1nnc(-c2ccco2)o1 +O=C1COc2ccc(C(=O)CSc3ccc(F)c(F)c3)cc2N1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cc2ccoc2s1 +COc1ccc(OC)c(CC(=O)NCCC2CC3CCC2C3)c1 +Cc1cc(C)c(S(=O)(=O)c2cnc(N)nc2)c(C)c1 +CN1C(=O)C2CCC1CN(C(=O)c1nnc3n1CCCCC3)C2 +CCOc1cccc(CNc2nccc(-n3ccc(C)n3)n2)c1 +CC(=O)c1cccc(NC(=O)c2cnc3n(c2=O)CCS3)c1 +COc1cc2c(cc1OC)CN(C(=O)c1n[nH]c3ccccc13)CC2 +CCC1CCCCN1C(=O)c1ccc(OC)c(OC)c1OC +CC(C)c1nnsc1CNC(=O)c1nc2ccccn2c1F +CCC(CO)NS(=O)(=O)c1cc(N)c(C)c(Cl)c1 +O=C(NCCCNC(=O)c1cc(F)cc(F)c1)c1cccc(O)c1 +COc1ccc(C)cc1NC(=O)c1cn(C)nc1C(F)(F)F +COc1cccc(CC(NC(C)=O)C(=O)Oc2ccccc2)c1 +Cc1nn(C)c(C)c1CCC(=O)NCCCn1cccn1 +Cc1cc(C)n(C2CCCN(C(=O)c3cncn3-c3ccccc3)C2)n1 +CC(=O)c1cccc(NC(=O)c2nccc3c(N)cc(C)cc23)c1 +Cc1nn(C)c2sc(C(=O)N3CCCC(n4cccn4)C3)cc12 +Fc1ccc(-n2ncc3c(N4CCOCC4)ncnc32)cc1F +Cc1nonc1CN(C)Cc1nc(-c2ccc(F)cc2)oc1C +CC(C)NC(=O)C1CCN(C(=O)c2cccc(Cl)c2)CC1 +O=C1CC2(CCN(C(=O)Cc3cccs3)CC2)Oc2ccccc21 +CCc1nc2c(s1)C(N(C)C(=O)c1ccoc1C)CCC2 +CNC(=O)C1CCCCN1C(=O)c1sc2nc(C)nc(C)c2c1C +CC(C)Cc1nc(CO)n(-c2ccc3c(c2)OCCO3)n1 +O=C(CC1C=CCC1)Nc1cccc(S(=O)(=O)N2CCCCC2)c1 +O=C(NCCCn1cccc1)c1csc(-c2ccccc2)n1 +CC(C)NC(=O)CCNC(=O)NCCc1c(F)cccc1F +CC(=O)Nc1cccc(NCc2cnc(-c3ccccc3)s2)c1 +CN(C)C(=O)CSc1nnc(-c2ccccc2Br)o1 +CCC(C)n1ncc(C(=O)NCC2(C)CCCC2)c1C1CC1 +O=C(NCC1(c2ccccc2Cl)CC1)c1ccon1 +COc1cc(Cc2ccc(O)c(OC)c2)ccc1O +COC(=O)C1(NC(=O)CC2C(=O)Nc3ccccc32)CCCCCC1 +COc1ccc(C(O)CNC(=O)c2ccco2)cc1OC +OCCCC1(c2ccc3c(c2)OCCO3)OCCO1 +COc1ccc(-n2ccc(CNC(=O)Nc3cnccc3C)n2)cc1 +Cc1ccc(F)cc1NCC(=O)N1CCN(C(=O)C2CC2)CC1 +CC(C)CNC(=O)c1ccc(N2CCCCC2)cc1 +Cc1csc(NC(=O)Cc2ccccc2F)n1 +CCC(=O)N1CCc2cc(C)c(S(=O)(=O)NC3CC3)cc21 +CCCCCC(=O)Nc1ccc(C#CCCO)cc1 +COc1ccc(C(=O)NCc2ccccc2OC)c(OC)n1 +Cc1nn(C(F)F)c(C)c1S(=O)(=O)N1CCCn2nccc21 +CCCCn1nc(C(=O)Nc2cccc3cn[nH]c23)ccc1=O +Cc1ccc(-c2noc(CCC(=O)NCc3ccccn3)n2)cc1 +CCc1nc(-c2noc3ccc(C(=O)NC4CC4)cc23)co1 +C#CC(OC(=O)c1ccccc1-n1cccn1)C1CC1 +COc1cccc(Nc2ncnc(Nc3cccc(C)n3)c2N)c1 +CCOCCSc1nc2ccccc2c(=O)n1CC1CCCO1 +COc1ccc(Cl)cc1NC(=O)Nc1cc2[nH]c(=O)[nH]c2cc1C +Cc1n[nH]c(C)c1CN(C)C(=O)Cc1ccsc1 +CC(=O)N(Cc1csc(COc2cc(C)cc(C)c2)n1)C(C)C +Cn1cnc(CNS(=O)(=O)Cc2cc(Cl)ccc2F)n1 +COc1ccc(NC(=O)CC(C)(C)C)c(OC)c1 +CCOC(=O)Cn1ccc(C(=O)c2ccc(-n3cccc3)cc2)c1 +Cc1cc2nnc(SCCN3CCOC3=O)n2c(C)n1 +CC(C)C1Oc2c(Br)cc(Cl)cc2NC1=O +CC(C)(C)OC(=O)N1CCC(Oc2nc3ccccc3s2)CC1 +COc1ccc(Br)c2c1C(C1CCC1)NCC2 +CCCc1noc(CCCC(=O)N2CCCC(c3ccn[nH]3)C2)n1 +CN(CC(=O)NC1(C(N)=O)CCCCC1)c1ncnc2[nH]cnc12 +CCn1cc(CNC(=O)CCC2CCCCC2)cn1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1nnc(C2CC2)s1 +Cc1ccccc1CN1CCN(C(=O)c2nnsc2C)CC1 +CCc1nnc(NC(=O)c2nn(C)c3ccc(C)cc3c2=O)s1 +Cc1cc(C)n(Cc2ccc(C(=O)NCc3c(C)nn(C)c3C)o2)n1 +CCC(Oc1ccccc1)C(=O)Nc1ccc(N(C)C(C)=O)cc1 +CC(CNC(=O)Cn1c(=O)[nH]c2ccccc21)N1CCOCC1 +CSc1ncc(C(=O)NCCCC(N)=O)n1-c1ccc(F)cc1 +CCC1CCc2sc(C(=O)NC(C)CO)cc2C1 +O=C(NCCc1ccc(F)cc1)NCCn1ccnc1 +Cc1csc(NC(=O)CSc2nnc(-c3ccco3)n2C)n1 +COCCN1CC(C(=O)NCc2cccc(C(F)(F)F)c2)CC1=O +CCN(CC)c1ncc2c(n1)CCC(C(=O)NCCOC)C2 +O=C(CCC1CC1)Nc1ccnn1C1CCCCC1 +CC(C)c1ccccc1NC(=O)c1cc(N)ccc1Cl +CCc1nc(C(C)NC(=O)Cn2c(=O)cnc3ccccc32)cs1 +O=C(NCCCn1cnc2ccccc21)c1cc2ccccc2c(=O)[nH]1 +CN(Cc1n[nH]c2c1CCCC2)c1ncnc2[nH]ccc12 +COc1ccc(Nc2nc3cc(C#N)ccc3[nH]2)cc1OC +Cc1cc(NC(=O)c2ccc(-c3cccnc3)nc2N)no1 +Cc1nc(C2=CCC(C)O2)sc1C(=O)N1CCCC1C1=NC=CC1 +CCN(CC)c1nnc(C)c2c(C)n(-c3ccccc3)nc12 +CCCNS(=O)(=O)c1cc(C(=O)NC(C)C)ccc1OC +COc1cccc(Cn2nc(-c3nccc4ccccc34)oc2=O)c1 +COCCN1CC(C(=O)N(C)C2CCc3ccccc3C2)CC1=O +CCC(=O)Oc1ccc(C(=O)Nc2cccc(O)c2)cc1OC +CCCNC(=O)c1nc(C)c(C)nc1C(=O)Nc1ccc(Cl)cc1 +CN(C)C(=O)COCC1CCC2C(CCN2Cc2nccs2)O1 +CCOC(=O)C(N)Cc1ccccc1-c1ccc(O)cc1 +Cc1[nH]ncc1CCCNC(=O)N1CCCC(c2nncn2C)C1 +COc1ccc(NC(=O)Nc2cc(F)ccc2OC)c(OC)c1 +CCOc1ccccc1C(=O)N1CCN(S(C)(=O)=O)CC1 +CCc1ccc(OC(=O)C2CCN(c3cnccn3)CC2)cc1 +Cn1cc(N)cc1C(=O)Nc1ccc2c(c1)CCC2 +COC(=O)C1CCCCN1C(=O)c1ccc(C(C)C)cc1 +CC(=O)N1CCC(c2cccc(Nc3nnc(C)s3)n2)CC1 +COc1ccc(C(=O)NCc2nc(-c3ccc(OC)cc3)no2)cc1 +Cc1noc2nc(-c3ccc(F)cc3)cc(C(=O)NCC(C)O)c12 +Cc1cccc(CNC(=O)COC(=O)c2cccs2)c1 +COC(C)C(=O)Nc1ncc(Cc2cccc(Cl)c2)s1 +O=C(NCc1ccccc1)c1ccc(N2CCOCC2)cc1 +CC1CCCN(C(=O)c2nc(-c3cnccn3)no2)C1 +CC(=O)Oc1c(C)cc(CNCc2snnc2C(C)C)cc1C +CC(C)OCCCNC(=O)N1CCN(c2ncccc2C#N)CC1 +COc1cc(NC(C)=O)ccc1NC(=O)NCc1ncc[nH]1 +CCOC(=O)c1[nH]c2ccccc2c1NC(=O)C1CC1 +Nc1cc(-c2ccc3c(c2)CCC3)nn1-c1ccccc1 +O=C(NCCc1cnn(-c2ccccc2)c1)c1cccc2ncccc12 +Cc1noc(C)c1CN(C)C(=O)CC12CC3CC(CC(O)(C3)C1)C2 +COc1ccc(CNC(=O)Cn2ccc3ccccc32)cc1 +Cc1csc(C(=O)N2CCC(Oc3ncccn3)CC2)c1 +N#CC1CCCN(C(=O)c2ccc(Br)cc2)C1 +CCc1c(C)sc2nc(-c3cccc(OC)c3)c(N)n12 +CCN(CC)C(=O)CSc1nnc2cc(C)c3ccccc3n12 +CCN(CC)c1ccc(C(=O)NCCCO)cc1 +CC(=O)N1CCC(NC(=O)Cc2cccs2)CC1 +CC(C)NS(=O)(=O)c1ccc2c(c1)NCC(C)(C)O2 +Fc1cc2c(c(C(F)(F)F)c1)CCNC2c1ncccn1 +CCN(CC1CCOC1)C(=O)NCc1cc(Br)cs1 +Cc1ccc2ncn(CC(=O)NCCC(C)C)c(=O)c2c1 +COc1cc2c(cc1OC)-c1c(c(=O)c1=O)C(C(C)C)C2 +Cc1nnc2n1CCN(Cc1nc(-c3ccco3)no1)C2 +Cc1nc(C)n(CC2CCCN2c2c(C#N)c(=O)n(C)c(=O)n2C)n1 +COc1cc(C(=O)N2CCCCC2C)cc(OC)c1C +O=C(Cn1ccc(=O)c2ccccc21)NC(Cc1ccccc1)C1CC1 +COc1ccc(NC(C)=O)cc1NC(=O)c1cc(Cl)ccn1 +Cc1ccc(C(=O)Nc2ccc(N)c(C(F)(F)F)c2)s1 +CCC(=O)Nc1ccc(NC(=O)COc2ccccc2)c(C)c1 +CC(=O)Nc1ccc(-c2nc3n(c2CO)CCS3)cc1 +CC(=O)N1CCC(C(=O)Nc2cccc(Cl)c2F)CC1 +Cc1nn(C)c(C)c1CCNC(=O)NCc1cnn(C)c1 +CCc1nc(CC(=O)Nc2cccc(F)c2)cs1 +COCc1cccc(C(=O)NC2CC(=O)N(Cc3ccccc3)C2)c1 +CS(=O)c1ccc(C(=O)OCC#Cc2ccccc2)cc1 +CNC(=O)N1CCC(NC(=O)c2cccs2)CC1 +CC(OCC1CC1)C(=O)N1CCC(O)(C(F)(F)F)CC1 +Cc1cccc(NC(=O)C(Cc2ccccc2)n2cnnn2)n1 +Cc1cc(N(C)CC2(CO)CCOCC2)n2nc(C)c(C)c2n1 +CCc1nnc(NC(=O)NCCS(=O)(=O)c2ccccc2)s1 +Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CC(C)C +O=C(COC1CCCC1)Nc1cnc(-c2cccc(O)c2)nc1 +Cc1ccccc1CN(C)C(=O)CN1CCOC(C)(C)C1 +CCN1CC(C(=O)Nc2cc(F)c(F)c(F)c2)CC1=O +CC(C)OC(=O)CCCNC1=NS(=O)(=O)c2ccccc21 +O=C(NCc1nnc2n1CCC2)Nc1ccc(Cl)c(F)c1 +CCC(CC)NC(=O)CSc1nc(N)cc(N)c1C#N +COC(=O)c1ccc(C)c(NC(=O)c2c(C)nn(C(C)(C)C)c2C)c1 +Cc1cc(NC(=O)c2cc(F)c(F)c(F)c2)ccc1S(N)(=O)=O +Cc1ccc(-n2nnc(C(=O)NCc3ccccc3F)c2C)cc1C +COc1ccc(CC(C#N)C(=O)N2CCOCC2)cc1O +CC(OC(=O)C1CCC1)C(=O)Nc1ccc(F)cc1 +CCC(NC(=O)Cn1nc(C)nc1C)c1ccc(Cl)cc1 +CC(C)NC(=O)Cn1c(=O)n(C)c(=O)c2ccccc21 +C=CCNC(=O)CSc1n[nH]c(=O)n1CC1CCCO1 +COc1ccc(CN(C)S(=O)(=O)c2cccc(Cl)c2)cc1F +CCC(=O)N1CCN(c2cc(Oc3cc(C)ccc3F)ncn2)CC1 +COc1ccc(C(=O)CNc2cc(C)ccc2OC)cc1 +Cc1nc(N(C)C(C)c2cccs2)sc1C(C)O +COC(=O)c1ccccc1Cc1ccccc1C(=O)OC +COc1ccc(-n2cc(CNC(=O)C3CC4C=CC3C4)nn2)cc1 +Cc1cc(C(=O)Nc2cc(Cl)ccc2OCC(F)(F)F)[nH]n1 +COc1ccc(Cc2nnc(SC)o2)cc1N +CNC(=O)CN(C)C(=O)Cc1csc(C(C)C)n1 +Cc1cccc(OC2CCN(C(=O)C(O)c3ccccc3)CC2)c1 +Cc1nn(CCC(=O)N2CCCCCC2)c2ccccc12 +Cc1cc(C)n(Cc2ccc(C(=O)NCCN3CCOCC3)cc2)n1 +CCOCCCNC(=O)C1CCN(C(=O)NC2CC2)CC1 +CC(=O)Nc1cccc(C(=O)Nc2ccccc2C(C)C)c1 +CC(C)N(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccccn1 +Cc1cc(C(=O)N2CCN(Cc3cc(C)sc3C)CC2)on1 +O=C(NCCc1ccccc1Cl)NCC1CCCO1 +CCCCOCC(=O)N1CCCCCC1c1ccco1 +CC1CCCC(OC(=O)CCNC(=O)OC(C)(C)C)C1 +CC(C)N1CC(C(=O)N(CCC#N)CCC#N)CC1=O +CC(=O)c1c(C)[nH]c(C(=O)N2Cc3ccccc3CC2C(N)=O)c1C +N#Cc1ccc(NC2CCN(C(=O)c3ccccc3F)CC2)nc1 +Cc1cc(C(=O)NCCCN2CCOCC2)nc(N2CCCCC2)n1 +Cc1nc2c(N)cccc2n1Cc1ccc(F)cc1 +COC(=O)c1ccc(COc2ccc(CO)cc2OC)cc1 +O=C(c1ccco1)N1CCC(c2ccc(O)cc2)CC1 +CN1C(=O)CCc2cc(NC(=O)c3n[nH]c4ccccc34)ccc21 +CCCC(NC(N)=O)C(=O)Nc1ccc(C(C)=O)c(C)c1 +Cc1ccc(C(=O)N(C)CC2CCCO2)c(=O)[nH]1 +CC(=O)N1CCN(C(=O)CCc2nc3ccccc3s2)CC1 +COCCNC(=O)c1onc(-c2cccc(Cl)c2)c1N +CC(Oc1cccc(Br)c1)C(=O)NC(C)(C)C +Cc1cc(C(=O)OCC(=O)N2C(C)CCCC2C)c2ccccc2n1 +CCc1noc(COc2ccc(-n3cncn3)cc2)n1 +CC(C)c1ccccc1OCCNC(=O)N1CCC(CC(N)=O)CC1 +CCOCC(O)CN1CCN(C(=O)c2c(C)noc2C)CC1 +Cc1cccc(OC(=O)C(C)NC(=O)c2ccco2)c1 +CCN1CC2(CC1=O)CN(C(C)=O)CCN(S(C)(=O)=O)C2 +Cc1csc(NC(=O)N(CC(C)C)CC(C)C)n1 +COc1ccc2c(CC(=O)N3CCC(C(=O)N(C)C)CC3)coc2c1 +CCOCCC(=O)Nc1cccc(Cl)c1Oc1cccnc1 +Cc1sc(NC(=O)CSc2nncn2C)c(C)c1C +Cc1ccc(C)c(S(=O)(=O)N(C)Cc2cnn(C)c2)c1 +COc1ccc(NC(=O)NCc2ncoc2C)cc1Cl +Cc1nc(CCC(=O)N(C)CC2CCN(c3ccccc3)C2)n[nH]1 +Cc1cc(CN(C)S(=O)(=O)c2ccc(C)s2)no1 +Cc1cccc(NC(=O)N(C)CCOCC2CC2)c1C +Cc1ccc(C(=O)N2CCc3ccccc32)cc1N(C)S(C)(=O)=O +CNC(=O)c1cc(OC2CC2)ccc1C(F)(F)F +COc1ccc(OC)c(C(=O)N(C)C(C)c2cccs2)c1 +O=C(CC1COCCN1C(=O)CCc1cccnc1)c1ccccc1 +CCOc1ccc(Cl)cc1CSc1nc(C)n[nH]1 +Cc1nnc(NC(=O)Cc2cccc3cccnc23)s1 +COCC(=O)N1CCCC(c2nc(CCNC(C)=O)cs2)C1 +CCCCN(CC)C(=O)CNC(=O)c1cc(F)cc(F)c1 +CN(CCC#N)C(=O)c1cc(Cl)ccc1OC(F)F +CCOC(=O)c1nnsc1NC(=O)c1ccccc1 +CC1CNc2cc(C(=O)CNCc3ccccc3F)ccc2O1 +Oc1ccc2c(c1Cl)C(c1cncnc1)NCC2 +Cc1cc(C)n2nc(CCCNC(=O)NC(C)C3CC3)c(C#N)c2n1 +Cc1ccc(F)cc1C(=O)NCCCNS(C)(=O)=O +Nc1nc2c(c(=O)[nH]1)CCN(C(=O)C1COc3ccccc3O1)C2 +O=C(CNC(=O)c1cccn1Cc1ccccc1)NC1CC1 +CN(C)C(=O)c1ccc2c(c1)N(C)C(CC(=O)NCC(F)F)CO2 +CC(C)COc1ccc(CNC(=O)c2cnn(C)c2)cc1 +O=C(Cc1c(F)cccc1F)Nc1nc(-c2ccc(O)cc2)cs1 +CC(OC(=O)c1cccnc1)C(=O)NC1CCCC(C)C1C +CCn1cc(S(=O)(=O)c2ccc(Cl)cc2)c(=O)c2ccccc21 +CCCC(C)N(C)S(=O)(=O)c1ccc(CNC(C)=O)s1 +COC(=O)C(C)NC(=O)c1cncc(Br)c1 +CN(C)C(=O)c1ccc(NC(=O)c2cc3ccccc3[nH]2)cc1 +COCCN1CC(C(=O)Oc2ccc(F)cc2)CC1=O +Cc1[nH]c2ccccc2c1C(=O)OCC1CC(=O)N(C2CC2)C1 +CC(C)c1ccc(NC(=O)NC2CCN(S(C)(=O)=O)CC2)cc1 +Cc1ncsc1-c1nc(Cn2c3c(sc2=O)CCCC3)no1 +CCN(CCC(=O)NCc1ccc(F)cc1)C(=O)c1ccoc1C +CCNC(=O)NC1(C(=O)NCCCOC)CCCC1 +Cc1cc(=O)cc(C2CCCN(C(=O)c3ccc(F)c(F)c3)C2)[nH]1 +Cc1ccc(-c2n[nH]c(N)c2-c2ccccc2)s1 +CCCc1n[nH]c(C2CN(C(=O)CCn3cncn3)CCO2)n1 +COc1ccc(CNC(=O)CCc2c(C)noc2C)cc1F +Cc1ccccc1N(C)C(=O)c1cccc(F)c1N +COc1ccccc1CCNC(=O)NCc1nc(-c2ccco2)n[nH]1 +Cc1cc(Br)ccc1NCC(=O)NCCC#N +CCSc1ccccc1NC(=O)C1COc2ccccc2O1 +Cc1nc(-c2ccncc2)ncc1C(C)NC(=O)C1C(C)(C)C1(C)C +CC(=O)N1CCCc2cc(NC(=O)c3scnc3C3CC3)ccc21 +N#Cc1ccc(Cl)cc1N1CCC(C2OCCO2)CC1 +Cc1nccn1-c1ccc(NC(=O)c2cccc(-c3ccoc3)c2)cn1 +COC(=O)c1sccc1NC(=O)c1cc(OC)cc(OC)c1 +CC(C)CNC(=O)NCc1cc(F)cc(Br)c1 +NC(=O)NCc1ccc(C(=O)Nc2ccnn2C2CCCCC2)cc1 +COCCCNC(=O)c1ccccc1NC(=O)c1ccccc1F +CC(Sc1ncn[nH]1)C(=O)N1CCN(c2ccccc2)CC1 +Cc1cc(NCC(=O)N(C)c2ccccc2)ccc1C(=O)NC(C)C +Nc1ccc2nc(C(=O)Nc3cccc(F)c3)cn2c1 +CC1c2ccc(F)cc2CCN1C(=O)CNC(=O)c1ccsc1 +CC1COCCN1C(=O)NCc1ccnc(OC2CCCC2)c1 +O=C(CC1OC(=O)c2ccccc21)NCc1ccc2c(c1)CCC2 +O=C(NCc1ccco1)NCC(C1CCOC1)N1CCOCC1 +Cc1ccc(CN(C)C(=O)CCC(=O)c2ccc3c(c2)OCCO3)o1 +CCOc1ncccc1C(=O)N1CCN(Cc2c(C)noc2C)CC1 +NC(=O)CC1CCCCN1C(=O)c1csc(-c2ccco2)n1 +O=C(COc1ccccn1)C12CC3CC(CC(C3)C1)C2 +COCC(NC(=O)c1cnc2ccc(C)cn12)c1ccc(C)o1 +COC(=O)c1sc2ccccc2c1CNC(=O)c1cnccn1 +O=C(Cn1c(SC(F)F)nc2ccccc21)NCCCO +CCC(C)C(NC(N)=O)C(=O)NCc1c[nH]nc1C +O=C(Nc1nccs1)c1cc(Br)ccc1Cl +Cc1c(CCC(=O)Nc2nn(C(C)(C)C)cc2C#N)cnn1C +COc1ncccc1CN(C)C(=O)NCc1cccc(F)c1 +Cc1ncc(CNC(=O)N2CCCC2c2ccncc2)s1 +Cc1csc(CNC(=O)c2cc(-c3cccc(F)c3)no2)n1 +CN1CCOc2ccc(NC(=O)CCC3CCCCC3)cc2C1=O +COc1cccc(C(=O)N(C)c2ccccn2)c1OC +CCCc1c(CO)nnn1Cc1ccc(Cl)cc1 +COCCn1cc(Nc2ccc(Cl)cn2)cn1 +Cc1cccnc1NC(=O)c1cc(C2CC2)nc2ccccc12 +Cc1ccc(C(=O)NC(C(=O)OC(C)c2cccnc2)C(C)C)cc1 +C=CCNC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +NC(=O)CN(CCC1CCCCC1)C(=O)c1ccccc1 +Cc1ccc(CNC(=O)N2CCOCC2C)c(N(C)C)c1 +O=S(=O)(NCc1cccc(O)c1)c1cccc(Br)c1 +Cc1cc(CNc2ccc(C)c(Br)c2)no1 +CS(=O)(=O)c1ccccc1NC(=O)CCSc1ccccc1 +N#Cc1cccc(CNC(=O)Nc2cnn(CC3CCCO3)c2)c1 +N#CCn1c(COC(=O)CCc2ccccc2)nc2ccccc2c1=O +O=C1CC(C(=O)OCCOc2ccccc2F)c2ccccc2N1 +c1ccc(-c2nc(-c3ccncc3)cc(N3CCCCC3)n2)nc1 +O=C(Nc1ccncc1)N1CCc2cc(Br)ccc21 +CN1CCNC(c2ccc3c(c2)CC(=O)N3C)C1=O +COCC(=O)Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1 +CC(CNc1ncc(F)c(N(C)C)n1)N(C)c1ccccc1 +Cc1ccc(C(N)=O)cc1NC(=O)N1CCCC1CO +CC(=O)Nc1cccc(NC(=O)c2cc(F)c(F)cc2Cl)c1 +COc1cc(OC)c(C(C#N)CC(=O)N(C)C)cc1OC +O=C(NCCc1nc2ccccc2[nH]1)c1n[nH]c2ccccc12 +CC(C)C(=O)Nc1cccc(C(=O)N2CCCC2)c1 +Cc1cc(C)n(-c2ccc(Br)cc2N)n1 +CC1=C(C(=O)N2CC=C(c3ccc(F)cc3)CC2)C(C)NC(=O)N1 +CCOc1ccc(C(=O)CCC(=O)N(C)C(C)C)cc1 +CC(C)OCCCNC(=O)c1ccc(Br)cc1O +CNS(=O)(=O)c1ccc(C(C)NC(=O)C2CC=CC2)cc1 +CC(C)c1nc(S(=O)(=O)NC(c2ccccn2)C(C)C)c[nH]1 +CCCN(C)S(=O)(=O)c1c(C)cccc1Cl +Cc1ccc(Cl)cc1NC(=O)CSc1nnc2ccc(N)cn12 +O=C(CC1CC2CCC1C2)NCCCn1cnc2ccccc21 +CCN(Cc1ccccc1NC(=O)c1cccnc1OC)C(C)=O +CC(=O)c1cccc(OCC(=O)NC(C)c2ccc(F)cc2)c1 +COCCSc1ccccc1C(=O)N1CCCC(C)C1 +O=S(=O)(NCc1ccc(-c2nccs2)cc1)c1ccccc1 +COc1ccc(F)cc1NC(=O)NCC(C)c1c(C)noc1C +CNC(=O)C1CN(C(=O)COc2ccc(F)cc2)CC12CCCC2 +Cc1ccc(C(=O)NCC2CN(Cc3ccccc3)CCO2)cc1C +O=C(Cc1ccc(F)cc1)N1CCN(CC(O)c2ccccc2)CC1 +CCc1nc(C(C)NC(=O)CCOc2cccc(Cl)c2)cs1 +CCOCCC(=O)NC1(C#N)CCC(CC)CC1 +COC(=O)C1CCCn2nc(-c3ccc(-n4ccnc4)cc3)nc21 +CC(C)COC(=O)N1CCCN(S(C)(=O)=O)CC1 +COc1ccc(CNc2nnc(C)s2)c(OC)c1 +CC1COCC(C)N1Cc1ccc(F)c(C(F)(F)F)c1 +NC(=O)c1ccc(NC(=O)c2cccc(O)c2)cc1 +Cc1cc(NC(=O)CCn2ccnc2C)ccc1Br +CCSc1ccccc1C(=O)NCc1nnnn1-c1ccccc1 +CSc1cnc(N)nc1-c1ccc(Cl)cc1 +CC(C)C(=O)NCCCNC(=O)N1CCc2cc(F)ccc2C1 +CSc1cccc(NC(=O)CC2(Cn3cnnn3)CCCCC2)c1 +Cc1ccc(C)c(C(C)NC(=O)c2c(C)noc2C)c1 +CCN(Cc1cccs1)C(=O)Cc1cccc(OCC#N)c1 +CCCNC(=O)C(N)c1ccc(OC)c(OCC)c1 +CC(C)N(C(=O)COC(=O)c1ccc(O)cc1)c1ccccc1 +CC(C)c1ccc(OCC(=O)NCc2nnc3n2CCCCC3)cc1 +CS(=O)(=O)N1CCCN(C(=O)c2ccnc(-n3ccnc3)c2)CC1 +O=C(NCCCSc1ncnc2nc[nH]c12)C1CCCC1 +CC1CCC(NS(=O)(=O)c2ccc3oc(=O)ccc3c2)CC1 +c1ccc(CN2CCc3nc(N4CCCC4)ncc3C2)nc1 +CC(c1ccco1)N(C(=O)Nc1ccccc1N(C)C)C1CC1 +CCCn1cc(C(=O)OCC)c(S(=O)(=O)N2CCOCC2)n1 +Cc1ccccc1CNC(=O)c1cccc(F)c1N +Nc1nccnc1C(=O)Nc1cnn(-c2ccccc2)c1 +Cc1noc(C)c1CC(=O)NCCN1CCCCCC1=O +Cc1ccc2cccc(C(=O)NCc3ccc4c(c3)OCO4)c2n1 +CC(NC(=O)C1CCOCC1)c1cccc(N2CCCC2)c1 +Cc1ccnc2nc(C(=O)N3CCCc4cc(Cl)cc(F)c43)nn12 +Cn1ccc(-c2cccc(Br)c2)c(C#N)c1=O +O=C(CCc1ccc(F)cc1F)NC(CO)c1ccccc1 +Cc1cn(CC(=O)N(C)Cc2cccc3ncccc23)c(=O)[nH]c1=O +CC(Oc1cccc(CO)c1)C(=O)NC1(C)Cc2ccccc2C1 +Nc1ccc2c(c1)CCC(=O)N2Cc1ccncc1 +O=C(NCc1cccc(Oc2ccccn2)c1)c1cccnc1 +CC(NCC(F)(F)F)(C(N)=O)c1cccc2ccccc12 +O=C(Cc1ccc[nH]1)Nc1ccc(C(F)(F)F)cc1 +O=C(CCSc1ccccn1)NCc1cc(F)ccc1F +CCOc1ccc(C2NC(=O)NC(C)=C2C(=O)OC(C)C)cc1OC +CN1CCC(NC(=O)c2sc3cccc(F)c3c2Cl)C1=O +CC(CNC(=O)c1ccc(=O)n(C)n1)c1nc(-c2ccccc2)no1 +Cc1nn(CC(C)C)c(C)c1S(=O)(=O)N(C)CCn1cccn1 +Fc1cc(Cn2cnc3ccccc32)c2ncccc2c1 +CC1Cc2cccc3c(=O)c(C(=O)NCCO)cn1c23 +COC(=O)CCN(C)C(=O)c1ccccc1SC +CCOC(=O)c1cnc(-c2cccc(OC)c2OC)nc1N +O=S(=O)(c1cnn(-c2ccccc2)c1)N1CCOc2ccccc21 +Cc1ccc(CCCC(=O)N2CCN(C3CCCC3O)CC2)cc1 +CN(CC(N)=O)C(=O)COc1ccc2ccccc2c1 +OCc1nnn(-c2ccccc2F)c1Cc1cccs1 +CC(C)CNC(=O)C(C)Sc1ncc(-c2ccccc2)n1C +COC(=O)C(NS(=O)(=O)c1cccc(Cl)c1C)C(C)C +O=C1CN(C(=O)C2CC(=O)N(C3CCCC3)C2)c2ccccc2N1 +CN(Cc1nccn1C(F)F)C(=O)NCCc1cc(F)ccc1F +CCn1c(=O)c2c(nc3n2CCCN3c2ccc(F)cc2)n(C)c1=O +CCOCC(=O)N(C)CC(=O)Nc1cc(Cl)ccc1OC +CSc1ccc(C(=O)NCCCc2cn[nH]c2C)cn1 +CC(C)(C)c1cc(-c2cn(Cc3ccoc3)nn2)n[nH]1 +COc1cc(Cl)c(C)cc1NCc1cncnc1 +Cc1nnc(SCC(=O)Nc2cccc(O)c2)o1 +COc1ccc(CC(C)Nc2c(C)n[nH]c2C)cc1 +Cc1ccc(O)c(NS(=O)(=O)c2ccccc2C)c1 +COc1ncccc1CNC(=O)N1CC2CCC1C2 +CNC(=O)C1CCN(C(=O)Cc2c(C)nc(C)[nH]c2=O)CC1 +COC(=O)CC(NC(=O)c1ccc(C)c(F)c1)c1ccc(C)cc1 +CN(C)C(=O)N1CCC2OCCCC2(COCC2CC2)C1 +Cn1nc(C(=O)NC(C)(C)C)c(=O)c2cc(Cl)ccc21 +COc1ccc(C2Cc3cccc(O)c3C(=O)O2)cc1O +Cc1ccc(C(=O)N=c2[nH]c3ccccc3[nH]2)c(=O)[nH]1 +c1ccc(-c2nc(CN3CCOC(C4CCCO4)C3)co2)cc1 +Nc1cccc(C(=O)N2CCN(c3nccs3)CC2)c1 +COc1ncccc1NC(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +COC(=O)N1CCC(CNS(=O)(=O)C(C)C)CC1 +O=C(CCCc1cccs1)NC1CCCc2[nH]c(=O)ccc21 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NC1CCCCC1 +CN(C)c1nccc(C2CN(S(=O)(=O)c3cn(C)cn3)C2)n1 +O=C(c1cc(=O)c2ccccc2[nH]1)N1CC2CCC1C2 +COC(=O)c1cc(F)c(C)c(NCC(=O)NC(C)(C#N)C(C)C)c1 +COc1ccc(C(=O)Cn2cccc(C)c2=O)cc1 +O=S(=O)(NCC1COCCO1)c1ccccc1Br +CN(Cc1cc(-c2ccccc2)no1)C(=O)CCCS(N)(=O)=O +O=C(NCc1nnc2n1CCCC2)Nc1ccc2c(c1)COC2 +CCC(=O)N1CCCN(C(=O)Nc2ccc(C(=O)NC)cc2)CC1 +CC(NC(=O)NCCNc1ncccn1)c1ccc(F)cc1F +O=C(NCCOCc1ccccc1)c1cnc(-c2ccccc2)[nH]c1=O +Cc1ccc(-n2nc(C)cc2NC(=O)CCC(C)(C)C)nn1 +COCC(=O)N(C)CCc1noc(-c2cc3ccc(OC)cc3[nH]2)n1 +COC(=O)c1sccc1NC(=O)c1cnc(C)cn1 +CCCNC(=O)c1cccc(CNS(C)(=O)=O)c1 +O=C(c1ccc[nH]c1=O)N1CC(c2nc(-c3cnccn3)no2)C1 +CC(C)NC(=O)C(C#N)Cc1cccc(Cl)c1 +COC(=O)c1nnn(-c2cccc3c(O)cccc23)c1N +C=CCCCN(C)C(=O)c1cc(OC)cc(OC)c1 +Cc1cc(C(=O)Nc2nc(-c3ccco3)c(-c3ccco3)s2)no1 +CN(C)C(=O)c1cn(CCC#N)nc1-c1cccs1 +Cc1ccc(-c2cc(CC3(C(=O)NC4CC4)CCOCC3)on2)cc1 +CS(=O)(=O)N1CCN(C(=O)COC(=O)c2cncc(F)c2)CC1 +CC1CN(S(=O)(=O)NCC23CC4CC(CC(C4)C2)C3)CC(C)O1 +C#Cc1cccc(NC(=O)Cc2c[nH]c3c(C)cccc23)c1 +CC(C)c1nnc2sc(-c3ccc4ccccc4n3)nn12 +Cc1ccc(F)cc1NS(=O)(=O)c1ccc(F)c(F)c1 +COc1ccc2[nH]cc(CC(=O)NCc3cnc(C)s3)c2c1 +COc1cccc(CNC(=O)Nc2cc(C#N)ccc2OC(F)F)c1 +CCCOc1ccc(OC)c(C(=O)c2ccc(N)cc2)c1 +CN(Cc1ccco1)C(=O)C1CCN(C(=O)Nc2ccccc2)CC1 +O=C(NCCc1coc(-c2ccccc2)n1)N1CCCC1 +COC(=O)C1(NCc2ccc(OC)cc2F)CC1 +Cc1ccc(C)c(S(=O)(=O)NCc2nc3ccccc3n2C)c1 +CCS(=O)(=O)c1ccc2oc(Nc3ccc(OC)cc3)nc2c1 +CCOCCNC(=O)COc1ccc(Cl)cc1C +NC(=O)c1nc(CNC(=O)Nc2ccnn2CC2CCCCC2)no1 +Cc1cn2c(CC#N)c(-c3cccnc3)nc2s1 +NC(=O)CSc1ncnc2nc(N3CCCC3)sc12 +CCCc1ccc2c(c1)C(Cn1cnnn1)NCC2 +NC(=O)N1CCCC(c2n[nH]c(C3CCCCC3)n2)C1 +N#Cc1ccc(C(=O)Nc2cc(F)cc(F)c2)cc1 +O=S(=O)(Oc1ccc2ncccc2c1)c1cn[nH]c1 +O=C(CCc1ccc2c(c1)OCO2)NC1CCCC1 +COc1cc(C)c(C)cc1-c1nc(CCO)cs1 +CCc1nc2ccccc2n1CC(=O)Nc1c(C)cccc1C(C)C +Clc1ccc2cccnc2c1CN1CCC2(CC1)OCCO2 +CCCCC(=O)NCc1ccc(OC)c(OC)c1 +CC(C)c1nnc2n1CC(NC(=O)C1COCCO1)CC2 +COCc1ccc(C(=O)N2CCCC(O)(CO)CC2)s1 +Cc1ccc(S(=O)(=O)Cc2coc(-c3cccs3)n2)cc1C +COc1cc(C2NCCc3c(OC)cc(O)cc32)ccn1 +COc1cccc(C(=O)NCc2nnc3n2CCCCC3)c1 +O=C(C1CN(c2cccc(F)c2)CCO1)N1CCC(O)CC1 +O=C(c1cn2cccnc2n1)N1CCC(Oc2ccccc2)CC1 +CC(C)N(C)C(=O)NCCCOc1ccc(F)cc1 +C=CCOC(C)C(=O)NCCc1c[nH]c2ccccc12 +NC(=O)c1ccc(C(=O)Nc2ccc3c(c2)COC3)cn1 +CN(C)C(=O)Cn1nc2c3ccccc3ncn2c1=O +CCc1nnc(NC(=O)N(C)C(C)c2ccccc2)s1 +CC(C)C(NC(=O)c1ccncc1F)c1nc(-c2cccnc2)no1 +C#CCOCC1CCCN(C(=O)Nc2ccc3c(c2)OCO3)C1 +Cc1csc2nc(CNC(=O)c3cccc(C(F)(F)F)c3)cn12 +Cc1nnc(SCCc2ccccc2Cl)n1N +O=C(NCc1ccc(O)cc1)c1cccc(-c2ccoc2)c1 +Cc1nc2ncnn2c(NC2CCOC2c2ccc(Cl)cc2)c1C +COc1ccc(-c2nn3c(CO)c(C)nc3s2)cc1 +COCCC1(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)CCC1 +O=C(Nc1ccc(F)c(Cl)c1)Nc1nnc(C(F)(F)F)s1 +COCc1cccc(CNC(=O)CNc2cc(F)c(F)c(F)c2)c1 +COc1ccc(CCN2CC(NC(=O)CNC(C)=O)CC2=O)cc1 +Cc1cc(C)nc(NC(=O)c2csc(-c3cnccn3)n2)n1 +COCCNC(=O)N1CCCC(C(=O)Nc2nccs2)C1 +CCN(c1ccc(NC(=O)c2ccc(NC(C)=O)cc2)cc1)C(C)C +Cc1cc(C)n(CCNC(=O)CCC2CCCC2)n1 +CCCCn1c(CN2CC(C)OC(C)C2)nc2c1c(=O)[nH]c(=O)n2C +O=C(Nc1nccs1)c1cc(F)c(Cl)cc1Cl +CCC(=O)N1CCc2nc3cccc(C)n3c(=O)c2C1 +NC(=O)NCc1ccc(C(=O)Nc2ccc(F)c(F)c2)cc1 +O=C(Cc1ccn(-c2ccccc2)n1)N1CCCC1 +Cn1cc(CC(=O)Nc2ccc(F)cc2)c2ccccc21 +O=C1CN(C(=O)C2CCN(c3ncccn3)C2)CCN1 +Cc1cc(C(=O)NCC(C)(C)N2CCOCC2)c(C)o1 +Cc1ccc(OC(=O)CCCCNC(N)=O)c(C)c1 +Cc1cc(C(=O)N2CCC(O)CC2)ccc1OC(C)C +CC1CC(NC(=O)N(CCCCO)C2CC2)C(=O)N1c1ccccc1 +Cn1cc(C2CN(Cc3cnc(C4CCCC4)s3)CCO2)cn1 +Cc1cnc(NC(=O)c2ccc(-c3ccc(F)cc3)o2)s1 +CC(C)COC1CCN(C(=O)NCC(C)Oc2ccccc2)CC1 +CCc1ccc(C(=O)N2CCN(C(=O)N(C)C)CC2)o1 +O=C(NCCc1cn[nH]c1)C1COc2ccccc2C1 +CCCCNC(=O)C1CCN(C(=O)c2cc(SC)ccc2C)CC1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1c(C)cccc1CC +CC(C)NC(=O)c1ccc(NC(=O)CCOC(C)C)cc1 +O=C(N1CCCC1)N1CCC2(CCCN(c3ncccn3)C2)CC1 +CCCC(=O)NCC(C1CCOC1)N1CCOCC1 +COCCn1c(SCC(=O)N2CCOCC2)nc2ccccc21 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)Nc1ccccc1 +COCCN(C)C(=O)NCCC(=O)Nc1ccc(C)cc1Cl +C#CCN1CCN(C(=O)NC2CCCN(c3ccccc3)C2=O)CC1 +CC1CC(C)CN(C(=O)c2c(-c3ccccc3)cnnc2N)C1 +CC1Nc2cc(F)c(F)cc2N(CCC#N)C1=O +O=C(CCOCC1CCCO1)Nc1ccc(-c2cc[nH]n2)cc1 +CC(=O)c1cccc(NCCC(O)c2ccccc2)c1 +COCCC(C)NC(=O)NC(C)c1ccc(F)cc1Cl +CCc1ccccc1NC(=O)c1cccnc1SC +CCCc1cc(C(=O)NCc2cc(Cl)c3c(c2)OCCO3)[nH]n1 +CCS(=O)(=O)c1ccc(-c2cccc(NC(=O)COC)c2)nn1 +CCn1cnnc1-c1cccc(NC(=O)C2CC3CCC2O3)c1 +CC(C)CNC(=O)c1ccc2c(c1)[nH]c(=O)c1ccncc12 +O=C(NC1CCCCCC1)c1ccc(-n2cnc3cccnc32)cc1 +Cn1nc(CNC(=O)c2cc(C3CC3)on2)c2c1CCCC2 +COC(C)(C)CNC(=O)NCc1ccnc(OC(C)(C)C)c1 +CC(=O)NCC(=O)Nc1ccccc1-n1nc(C)cc1C +Nc1[nH]ncc1Cc1cccc(Br)c1 +CCCN(CCC)S(=O)(=O)c1ccccc1F +CN1CCN(S(=O)(=O)N2CCN3C(=O)CN(C)C(=O)C3C2)CC1 +Cc1ccc(CNC(=O)CCn2ncc3c(C)cccc32)cc1 +CNC(=O)c1ccc(CN(C(=O)OC(C)(C)C)C2CC2)cc1 +CCN(CC)C(=O)c1ccc(NC(=O)c2sc(C)nc2C)cc1 +O=C(c1cccc(S(=O)(=O)N2CCCCC2)c1)N1CCC1 +CCOc1cccc(C(=O)Nc2cccc(OC(=O)CC)c2)c1 +C=CCN(Cc1ccc(OC)cc1)C(=O)C(C)NC(C)=O +O=C(c1cnc(-c2cccnc2)[nH]c1=O)N1CCC1c1ccccc1 +Cc1noc(C2CCCN(C(=O)C3(c4ccccc4)CCCC3)C2)n1 +CS(=O)(=O)N1CCCC12CCCN(Cc1cccs1)C2 +CCN(C(C)COC)S(=O)(=O)c1cn(C)nc1N +CCSc1cc(C(=O)Nc2cccc(N3CCNC3=O)c2)ccn1 +Cc1ccc(NS(=O)(=O)c2ccc(-c3nnc(C)o3)o2)c(F)c1 +Cc1cc(Cl)ccc1OC(C)C(=O)NCCOc1cccnc1 +COc1ccc(NC(=O)c2cccc(C)n2)cc1OCC(F)(F)F +O=C(CCc1ccccc1)N1CCn2cc(Cn3cncn3)nc2C1 +COc1ccc(CCNC(=O)C2Cc3ccccc3CN2)cc1OC +CCOc1ccccc1CNC(=O)c1c(Cl)cnn1CC +CCc1ccc(OC)c(CC(=O)N2CCNCC2)c1 +O=C(c1ccccn1)N1CCCCCC1Cc1cccs1 +CC1COCCN1C(=O)c1cccc(CN2CCCC2=O)c1 +Cc1noc(C)c1S(=O)(=O)Nc1ccccc1N1CCCCC1 +CC(=O)Nc1ccc(C2(C(=O)NC3CC3)CCCCC2)cc1 +CCOc1ccc(-c2nc3c(=O)n(C)c(=O)nc-3n(C)n2)cc1OC +COc1ccccc1-c1ccc(SCC(N)=O)nn1 +Cc1snc2sc(C(=O)c3ccccc3)c(N)c12 +Cc1nc(CNc2ccc(C(=O)NC(C)C)cc2)cs1 +Cc1cc(CNc2cc(-c3ccccc3F)nc3ccnn23)nn1C +COc1cc(=O)n(CC(=O)NC2CCCCC2)nc1-c1ccccc1 +CNC(=O)CN1CCN(C(=O)CNC(=O)c2ccccc2C)CC1 +O=C(c1ccc(NCc2ccc(F)cc2)cn1)N1CCCCC1 +Cc1c(C(=O)NCCc2ccc3c(c2)OCO3)oc2c1C(=O)CCC2 +CC(=O)c1ccccc1-c1c(N)n[nH]c1-c1ccccc1 +COc1ccc(NC(=O)NCc2ccncc2)cc1OC1CCCC1 +CC(C)CC(N)C(=O)OCc1ccc(Cl)cc1 +Cc1ccccc1-n1c(C)nnc1SCC(=O)NCC(C)C +O=S(=O)(c1cccs1)N1CCOC(c2ccccc2)C1 +CC(O)CNC(=O)Nc1nnc(-c2ccccn2)s1 +Cn1nc(C(=O)OCc2cc3ccccc3o2)ccc1=O +COc1ncnc2c1CN(Cc1cc(-c3ccccc3)no1)CC2 +O=C(COc1ccc2ccccc2c1)Nc1nc(C2=NC=CC2)cs1 +CC1CC1C(=O)NC(c1ccccc1)c1ccncc1 +COCCOC(=O)C(C)n1nnc(C(N)=O)c1C +COC(=O)C1CN(C(=O)c2ccco2)CCN1C(=O)C1CCCC1 +CC(C)(C)OC(=O)C(N)C1C(=O)Nc2ccc(F)cc21 +NC(=O)COc1ccc(C(=O)OCc2cccc(F)c2)cc1 +CCCCN(C)C(=O)C(C)NS(=O)(=O)c1ccccc1 +O=C(c1ccc(-c2ccccc2)cc1)N1CCc2nocc2C1 +O=C(CCC(O)C(F)(F)F)Nc1ccc(F)cc1 +CCOC(=O)C(N)Cc1ccc(OC(C)(C)C)cc1 +CN1C(=O)C(C)(C)c2cc(C(O)Cc3ccccc3)ccc21 +Cc1cc(NCC(=O)NC(C)(C#N)C(C)C)ccc1C(=O)NC(C)C +CNC(=O)CSc1nnc(-c2cccc(Br)c2)n1N +COc1ccccc1C(CNS(C)(=O)=O)OC +COCCNC(=O)NC1CC(=O)N(Cc2ccccc2)C1 +COc1cc(C(=O)N2CCN(C(=O)Cc3ccc[nH]3)CC2)ccc1C +O=C(CN1CCc2sccc2C1)NCC1COc2ccccc2O1 +Cc1ccc(F)cc1S(=O)(=O)N(C)Cc1ccoc1C +N#CCCCSc1nc(C2CC2)n(-c2ccccc2)n1 +CCC(c1ccccc1)C1CCCN1C(=O)c1cnc(C)cn1 +CC(C)CNC(=O)c1cccc(NCc2ccncc2)c1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(C)no3)CC2)cc1 +COc1ccccc1NC(=O)N1CCc2[nH]cnc2C1c1ccccn1 +C#CCN1CCC(C(=O)Nc2ccc3c(c2)NC(=O)CS3)CC1 +CCCCN(Cc1cc2cccc(C)c2[nH]c1=O)C(C)=O +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)Nc1nccs1 +CCOC(=O)c1oc2c(c1C)-c1nc(C)sc1CC2 +CCC(=O)Nc1cc(C(=O)N(C)c2ccccc2)ccc1OC +CN(C)C(=O)c1cc(NC(=O)CCCc2cccs2)ccn1 +CCc1nc(C(=O)NCc2cc[nH]n2)nn1-c1ccccc1Cl +COc1ccnc(NC(=O)c2ccc(-n3cncn3)cc2)c1 +N#CCCN(Cc1ccc(O)c(Cl)c1)Cc1ccccn1 +O=C(NCc1ccoc1)c1csc2c1CCCC2 +CCC(CC)C(=O)Nc1nnc(C(CC)CC)s1 +CCCc1n[nH]c(C2CN(C(C)C(=O)N(C)CCC#N)CCO2)n1 +COc1ccc(NC(=O)CS(=O)c2cccc(Cl)c2)cc1 +Cn1nccc1-c1nn2c(-c3cc(Cl)ccc3F)nnc2s1 +Cc1cccc(NC(=O)CN(c2ccccc2)S(C)(=O)=O)c1 +O=C(COc1ccccc1)OCC(=O)N1CCCCCC1 +NC(=O)C1(CNC(=O)Cn2nc3ccccn3c2=O)CCOCC1 +O=C(c1c[nH]c(=O)cn1)N1CCC(c2ccc3ccccc3c2)C(O)C1 +COc1cccc(C(=O)OC2CCCC(OC)C2)c1 +Cc1cc(NC(=O)N(C)C2Cc3ccccc3C2)no1 +OC(C=Cc1ccccc1)Cc1nc2ccccc2[nH]1 +CCC(CO)NC(=O)NC1CCN(C(=O)C(CC)CC)CC1 +CC(C)CN1CCOC(CNC(=O)CSc2ccccc2)C1 +CCn1ncc2c1CN(C(=O)c1ccc3c(c1)OCO3)CC2COC +COc1ccc(-c2nnc(SCC(=O)Nc3ccncc3)o2)cc1 +O=C(NCCc1cnc(-c2ccccc2)[nH]1)c1ccc(F)cc1 +CSc1ncccc1C(=O)N1CCCCC1c1cccc(F)c1 +O=C(c1nccc2ccccc12)N1CCCC1(CO)Cc1ccccc1 +CC(C)(O)CCc1ccc(C(=O)N2CCC3(O)CCCCC3C2)cc1 +Cc1ccc(C2CC2C(=O)NCC(C)(C)c2ccncc2)s1 +COc1cc(C)c(C(C)NC(=O)N(C)Cc2ccccn2)cc1OC +CCOc1cc(C#N)ccc1OCC(=O)N(C)Cc1ccc(F)cc1 +O=C(CCc1nc(-c2ccco2)no1)OC1CCCCC1 +O=C(CNC(=O)c1ccccc1-c1ccccc1)NCc1ccco1 +COc1ccc(F)cc1C(=O)COC(=O)c1ccc(C(N)=O)cc1 +C=CCNC(=O)N(CC)Cc1ccc(OC)c(OC)c1 +COc1cccc(CNc2nc3sccc3c(=O)n2C)c1 +O=C1NC(c2cccc(OC(F)(F)F)c2)Nc2ccccc21 +Cc1nonc1C(=O)NC1CCC(OC(C)C)CC1 +N#Cc1ccc(CN2CC3NC(=O)COC3C2)cc1 +COCC1CN(Cc2ccoc2)Cc2cn(CC3CCOCC3)nc21 +O=C(NCc1ccc2c(c1)OCO2)c1coc(-c2ccccc2)n1 +CCc1ncc(C(=O)N2CCCN(c3ccccc3C#N)CC2)s1 +Cc1ccc(C)c(OC(C)C(=O)NCCN2CCOCC2)c1 +CN(CCCNC(=O)NCCO)c1ccccc1F +CNC(=O)COC(=O)c1nc(-c2ccccc2)n2c1CCCCC2 +Cc1ccc(CC2COCCC2S(N)(=O)=O)cc1 +O=C(Nc1ccnc2c(C(F)(F)F)cccc12)c1ccncc1 +COc1cccc(CNC(=O)C2CCC(=O)N2Cc2cccs2)c1 +O=C(CCCc1nnc(-c2ccccc2)o1)NCC1CCCO1 +Cc1cccc(NC(=O)c2sc(-c3cccnc3)nc2C)c1 +Cc1ccccc1CNC(=O)NC(C)c1ccc(-n2cncn2)cc1 +CNC(=O)C1(C)CN(Cc2cn(C)c3ccc(F)cc23)CCO1 +CCOC(=O)C(NC)c1nc2ccc(F)cc2s1 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)Nc1ccc2c(c1)OCO2 +CN(CC(=O)Nc1cnn(-c2ccccc2Cl)c1)S(C)(=O)=O +COc1cccc(OC)c1CNc1ccc(C)nc1 +COc1cccc(NC2CCN(C(=O)c3cn(C)nc3C)CC2)c1 +CCOC(=O)c1nn(-c2cccc(C(F)(F)F)c2)cc1C(C)=O +CC1CN(C)CCN1C(=O)c1cccnc1-n1cncn1 +O=C(NCc1cccc(F)c1)c1cc(-c2cccs2)on1 +CC(C)N1CC(C(=O)NCC(Cc2ccc(F)cc2)C(N)=O)CC1=O +COc1cccc(CNC(=O)c2cnc3c(C)cccn3c2=O)c1 +CCc1ccc(-c2nnn(CC(=O)NC(C)c3cccs3)n2)cc1 +COc1ccc2c(c1)CCN2S(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1noc(C)c1CN(C)c1nccc(-c2ccccn2)n1 +CCc1ccc(OC)c(-c2cnn(C)c(=O)c2N)c1 +COc1ccccc1N1CCN(C(=O)Cn2nccc2C)CC1(C)C +COc1ccc(NC(=O)CSc2nnc(C(F)(F)F)n2C)cc1 +O=C1Cc2cc(C(O)c3ccc(Cl)cc3)cc(F)c2N1 +COc1ccc(C(=O)N2CCC(c3nc(C)cs3)CC2)c(O)c1 +O=C(Cn1nnc(-c2ccccc2)n1)N(Cc1ccsc1)C1CC1 +CCCn1ncc(-c2cc(F)ccc2OC)c(C#N)c1=O +CCCC(=O)N1CCCC1C(=O)Nc1cc(F)c(OC)cc1OC +COc1ccccc1C(=O)NCc1c(C)cc(C)[nH]c1=O +Cc1cc(COC(=O)c2cnn(Cc3ccccc3)c2)on1 +COc1ccc(F)c(NC(=O)CN(CCc2ccccc2)C(C)=O)c1 +COc1cccc(NC(=O)CCC(=O)c2ccc(F)c(F)c2)c1 +COc1ccccc1CNC(=O)Cn1nc(C)nc1-c1ccccc1 +O=C1Nc2cc(Cl)ccc2C1(O)C(F)(F)F +COC(=O)Nc1ccc(OC(=O)C2CC2c2ccc(F)cc2)cc1 +COc1cc(C)sc1C(=O)NC(C)c1ccc2c(c1)CCC(=O)N2 +COc1ccccc1N1CCN(c2ccc(S(N)(=O)=O)cn2)CC1 +Cn1cnc(CNC(=O)N2CCN(Cc3ccccc3)C(C#N)C2)n1 +Cc1csc(CNC(=O)c2ccccc2C(=O)c2ccccc2)n1 +CCOc1ccccc1CCC(=O)c1ccccn1 +CC(C)OCCCC(=O)N1CCCC1c1ccncc1 +N#Cc1ccc(N2CCN(C(=O)c3cc4ccccc4s3)CC2)nc1 +CCCNC(=O)c1cccc(NS(=O)(=O)c2ccccc2)c1 +O=C(Nc1cccnc1)c1cnc(N2CCOCC2)c2ccccc12 +N#CC(C(=O)C(c1ccccc1)N1CCCCC1=O)c1ccccn1 +Cc1[nH]c2ccccc2c1C(=O)NCc1ccccc1OC(F)F +Cc1ccc(C=c2sc(=CC(=O)c3ccco3)[nH]c2=O)cc1C +O=C(NCC1CCC(c2ncncc2-c2ccccn2)CC1)C1CC1 +CN(c1ncccn1)C1COC2(CCCN(c3nncs3)C2)C1 +Cc1ccc(F)c(OCC(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c1 +Cc1sc2nc(C(C)Sc3nncn3C)nc(N)c2c1C +Cc1ccc(C(CNC(=O)c2ccccc2)N2CCOCC2)o1 +NC(=O)c1ccc(NC2CCN(c3c(F)cccc3F)C2=O)cc1 +CC(Oc1ccc(F)cc1F)C(=O)N1CCC(=O)CC1 +N#Cc1ccc(N2CCCC(Nc3nccnc3C#N)C2)c(F)c1 +COc1cc(CC(=O)OCc2nc(N)nc(N(C)C)n2)ccc1C +COC(=O)c1ccc(C(=O)N(C)Cc2ccc(F)cc2)cc1 +NC(=O)C1CCCN(C(=O)Cn2cc(Br)cn2)C1 +Nc1ccc(Cn2c(C3CC3)nc3ccccc32)cn1 +c1cnc(NCCCn2cnc3ccccc32)nc1 +O=C(COC(=O)C1COc2ccccc2O1)c1ccc(Cl)cc1 +COc1ccc2c(c1)CCc1c(C(=O)NCc3ccco3)noc1-2 +Cc1cnc(NC(=O)C(OCC2CCCO2)C(C)C)s1 +CCC1CCCCC1NC(=O)c1cc(NC(C)=O)cc(NC(C)=O)c1 +Cc1cc(-c2ccc(=O)n(CCNC(=O)C3CCC3)n2)c(C)o1 +CC(O)CN1CCN(CCOc2c(Cl)cccc2Cl)CC1C +CCc1ccc(Cl)c(CC)c1NC(=O)NCCCOC +CC1(NC(=O)c2[nH]c(=O)[nH]c(=O)c2N)Cc2ccccc2C1 +Cc1nc(NCC(C)O)c2cccc(N)c2c1Br +CC(=O)NC(CC(=O)NCc1ccccc1F)c1ccccc1 +CC(NC(=O)Cn1nnc2ccccc21)c1ccccc1 +Cn1cc(NC(=O)Nc2ccccc2N2CCCC2=O)cn1 +c1cncc(CNc2ccc(-c3cnco3)cc2)c1 +O=C(CCSc1ccccc1)Nc1ccccc1N1CCOCC1 +C=CCNC(=O)C(CC)N(c1ccccc1)S(C)(=O)=O +COc1ccc(-c2nnc3ccccn23)c(OC)c1 +Cc1ccc(OCC#CCNC(=O)c2ccc[nH]c2=O)cn1 +CCOC(=O)C1CCCN(C(C)C(=O)c2ccc(N)cc2)C1 +Cn1cc(-c2n[nH]c3cc(N)ccc23)c2ccccc21 +CCOC(=O)CCC(=O)c1ccc2c(c1)CCN2C(C)=O +CCc1ccc(S(=O)(=O)NCCC(=O)OC)cc1N +Cc1cc(C)n(C2CCCN(C(=O)c3ccc(C)n(C)c3=O)C2)n1 +CCOc1cc(C)c(C(=O)CCC(=O)NC2CC2)cc1C +CN(C(=O)NCc1ccc(-n2cnc3ccccc32)nc1)C1CCC1 +CCCCNC(=O)NCCCn1cc(Br)cn1 +COC(=O)c1sccc1S(=O)(=O)N(C)c1cc(C)ccc1C +CCOC(=O)c1cc(-c2c(C)ccc3ccccc23)nn1CCO +Cn1c(=O)c2ccc(C(=O)NC3CCCCC3)nc2n(C)c1=O +O=C(Cn1ncc2cccn2c1=O)N1CCOCC1 +CCNC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(OC)nn1 +Fc1ccccc1Cc1nc(-c2ccncc2)no1 +O=C(Nc1ccncc1)C1CC(=O)N(C2CCCC2)C1 +C=CCn1c(=O)oc2cc(S(=O)(=O)N3CCCCC3)ccc21 +Cc1cc(C(CO)Nc2ccccc2F)ccc1F +COC(=O)CC1CCCCN1C(=O)c1ccoc1 +O=C(OCc1cc2ccccc2[nH]c1=O)C1CC=CC1 +CN1C(=O)c2cc(Cl)ccc2NC1C1=Cc2ccccc2OC1 +CC1CCC(C(=O)N2CCC(OCc3ccccc3F)CC2)CC1 +CCCn1c(C)cc(C(=O)COc2ncnc3ccccc23)c1C +O=C(CCCC(=O)c1ccc(F)cc1)NCc1cscn1 +COc1ccc(C(=O)N2CCC(O)CC2)cc1F +CCn1cnnc1SC(C)C(=O)Nc1ccc(F)c(F)c1 +COc1ccc(NC(=O)c2ccc(S(C)=O)cc2)c(Cl)c1 +Cc1c(CCC(=O)NCC(C)(C)c2ccncc2)cnn1C +COc1ccc(F)cc1NC(=O)c1cnn(C2CCOCC2)c1C +CC(NCc1ccccc1F)C(O)c1ccc(F)cc1 +CCN(CCC#N)C(=O)CSc1nnc(-c2ccccc2C)n1C +O=C(CCC1CCCC1)NCC(=O)Nc1ccc2c(c1)CC(=O)N2 +CC(C)c1nc(C(C)NC(=O)c2cc3ccccc3[nH]2)cs1 +COCCNC(c1ccc(F)cc1)c1nccs1 +CCCOC(=O)Cn1[nH]c(=O)c2ccccc2c1=O +Cc1nc(N2CCCC(c3cc[nH]n3)C2)c2cccnc2n1 +CCCS(=O)(=O)Nc1ccc2c(c1)CCC(=O)N2C +NC(=O)c1ccc(COC(=O)c2c3c(nc4ccccc24)CCC3)cc1 +O=C(c1ccncc1)N1CCOC2C(Oc3ncccc3F)CCC21 +CC(C(=O)NCCc1ccc(O)cc1)n1cncn1 +CC(O)(CNS(=O)(=O)Cc1ccc(Cl)cc1)C1CC1 +COCCNCC(=O)c1ccc(Cl)cc1Cl +O=C(Cn1nnc2ccccc21)N1CC(C(=O)N2CCCCCC2)C1 +Cc1cnc(NC(=O)c2c(C)[nH]c3ccccc23)s1 +CNC(=O)NCC(=O)N1CCNC(=O)C1C(C)C +COCCCNC(=O)C1(Cc2nc3ccccc3s2)CCCC1 +Cc1ccc(S(=O)(=O)N(C)C2Cc3ccccc3C2)s1 +Cc1cc(NC(=O)COC(=O)C2CCCCC2)no1 +N#Cc1ccccc1N1CCCN(C(=O)c2ccc[nH]c2=O)CC1 +COCc1cccc(CNC(=O)c2c(C)cc(C)[nH]c2=O)c1 +COCCCC(=O)Nc1ccc(C(=O)NC2CCCCC2)cc1 +O=C(Nc1cc(Cl)ccc1NC1CC1)C1CC2CCC1O2 +CCN(C(=O)c1ccc(F)c(Br)c1)c1ccncc1 +CC(C)CCOC(C)C(=O)Nc1nc2c(s1)CCC2 +CC(C)(C)n1cc(C#N)cc1NC(=O)NCCCc1nccs1 +Nc1ccc(N2CCCC(O)C2)cc1C(F)(F)F +Cc1cc(CNS(=O)(=O)c2cc(C)c(Cl)cc2Cl)c(C)o1 +COc1cc(CN(c2ccc(F)cc2)S(C)(=O)=O)cc(OC)c1 +Cn1c(=O)oc2cc(NC(=O)NCC(C)(C)C(N)=O)ccc21 +CC1CCC(C)N(C(=O)c2scnc2C2CC2)C1 +CCOC(=O)C(C)n1nc(CC)n2c(cc3occc32)c1=O +COC(=O)c1cc2c(=O)n(CCc3ccccc3)ccc2nc1C +CN1C(=O)COc2ccc(C(=O)NCCC3=CCCCC3)cc21 +COc1cc(S(=O)(=O)N(C)C)c(OC)cc1C +C#CCNC(=O)COC(=O)c1cccc(OC)c1O +CC(C)COCCNC(=O)N(C)Cc1ccccc1 +O=C(Nc1nccs1)c1ccc2ccccc2n1 +Cc1c(NC(=O)CNCc2ccccc2)cccc1NC(=O)C1CC1 +c1ccc2oc(Sc3nnnn3C3CC3)nc2c1 +CC(C)n1c(=O)c(NCc2cccc(Cl)c2)nc2ccncc21 +CCn1c(C2CCN(C(=O)c3ccccc3C)C2)nc2cccnc21 +O=C(NC1CCCc2[nH]c(=O)ccc21)c1sccc1C1CC1 +Cc1cnc(CNC(=O)c2ccc(-c3cscn3)cc2)s1 +CCCOc1cc(C)ccc1NC(=O)NCc1ccnc(OC)c1 +N#Cc1ccc(CN(CC(=O)NC2CC2)Cc2ccc(C#N)cc2)cc1 +COc1ccccc1NC(=O)c1ccc2c(c1)OCCO2 +O=S(=O)(NCC1CCCC1O)c1ccc(F)cc1C(F)(F)F +Cc1cccnc1NC(=O)CN(C)C(=O)OC(C)(C)C +Cc1nn(C)c2nc(N3CCN(C(=O)c4nc[nH]n4)CC3)sc12 +C#CCNC(=O)Cc1csc(-c2ccc(C)cc2)n1 +Cn1ncc2ccc(F)c(C(=O)c3ccccc3)c21 +O=C(Cn1c(C2CC2)nc2ccccc21)NCC(F)(F)F +CCC(C)(C)OCC(O)CN1CCN(c2ccccc2)CC1 +C#CCN1CCC(C(=O)N2CC(=O)NC3CCCCC32)CC1 +O=C(c1cnccn1)N1CCN2CC(Oc3cccnc3)CC2C1 +CC(C)COc1ccc(CCC(=O)Nc2cccnc2)cc1N +CC1(CNC(=O)NC(CO)Cc2ccccc2)CCCC1 +Cc1ccc(C(C)NC(=O)c2ccc(-n3cnnn3)cc2)o1 +COC(=O)CN(C)C1c2ccccc2-c2ccccc21 +COc1cccc(CNC(=O)c2snc(-c3ccccn3)c2N)c1 +Cc1noc(C)c1CSc1ccc2ccccc2n1 +CNC(=O)OCc1nc(-c2ccccc2)n(C)c1COC(=O)NC +Cc1cc(C)n2nc(SC(C(=O)N(C)C)C(C)C)nc2n1 +Cc1ccc(C(=O)N2CCCC2c2ccc3c(c2)OCCCO3)cn1 +COCC(O)CN(C)C(=O)c1ccc(Cl)cc1 +Cc1ccc(C(O)CCC(=O)NC2CCCC2)c(C)c1 +COC(=O)CCn1c(C(F)(F)F)nc2cc(O)ccc21 +O=C(COC1CCCCC1)NCc1ccccc1CO +COCCOc1cccc(C(=O)N2c3ccccc3CC2C(N)=O)c1 +CCOc1ccc(C(=O)Nc2cccn(C)c2=O)cc1OC +Cn1cc(S(=O)(=O)Nc2cccc(C(F)(F)F)c2)cn1 +CC(C)CCNc1ncnc(Nc2nccs2)c1N +Cc1cc(C(=O)N=c2[nH]ncn2C)c(F)cc1F +CC(C)N(C)C(=O)c1ccccc1S(C)(=O)=O +N#CCC(=O)NCc1ccccc1OCc1ccccc1F +Cc1noc(CNS(=O)(=O)c2cc(F)ccc2F)n1 +COc1ccc(CN(C)C(=O)c2cc(OC)c(C)c(OC)c2)cc1F +COc1ccccc1CCNS(=O)(=O)N1CCOCC1 +O=c1cc[nH]c(C2NCCc3cc(Cl)c(O)cc32)c1 +CCOc1ccc(C(=O)CCC(=O)Nc2c(C)cc(C)cc2C)cc1 +O=C(Nc1cc(F)cc(F)c1)c1cnc(C2CCCO2)s1 +CCCN1CC(NC(=O)c2ccc(-c3ccccc3Cl)o2)CC1=O +CCCN(CC(=O)OC)S(=O)(=O)c1ccc(Cl)c(Cl)c1 +CCC1CN(CC(=O)N(C)CCC#N)c2ccccc2N1 +CCSc1ccccc1NC(=O)NCc1ccncc1 +COCCNC(=O)CNC(=O)Cc1ccc(F)c(Br)c1 +Cn1c(SCC(=O)c2c[nH]c3ccccc23)nnc1-c1ccco1 +Cc1cccc(C2=CCN(C(=O)c3ccnc(-n4ccnc4)c3)CC2)c1 +Cc1ccc(C)c(C(=O)OCC(=O)NCc2ccc(F)cc2)c1 +COc1ccc(S(=O)(=O)Nc2cc(F)ccc2C)c(OC)c1 +CC(=O)Nc1cccc(C(C)NS(=O)(=O)c2cccs2)c1 +COCC(C)(CCO)NC(=O)NCC1CCCO1 +Cn1c(=O)ccn(CC(=O)N2CCC(C(N)=O)CC2)c1=O +CCn1cc(C(=O)N2CCN(C(=O)c3ccc(F)cc3F)CC2)cn1 +CC(O)CNC(=O)C1c2ccccc2Oc2ccccc21 +CC(C)N(C(=O)C1CCN(C(=O)N(C)C)CC1)c1cccc(C#N)c1 +Nc1ccc(F)cc1C(=O)Nc1cccc(CO)c1 +O=C(Nc1ccccc1F)c1ccc(CN2CCCCC2=O)cc1 +CCOc1cc(C)c(-c2onc(C)c2N)cc1Cl +COc1ccccc1CC(C)CC(=O)N1CCCC(n2cncn2)C1 +FC(F)(F)c1cc(-c2ccccn2)nc(N2CCOCC2)n1 +CSc1ccc(NC(=O)c2ccc(-c3nc(C)n[nH]3)cc2)cn1 +CC(C)C(=O)NCc1ccc(S(=O)(=O)NC2CC2)cc1 +CC(=O)c1sc(CCNCc2ccccn2)nc1C +CCOC(=O)c1nc2ccccc2nc1NCc1ccncc1 +Cc1sc(NC(=O)COC(=O)c2ccccc2N)c(C#N)c1C +CC(C)NS(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCc1nc(C)c(C(=O)N(C)Cc2csc(C(C)C)n2)o1 +CCc1ccc2nc(-c3cnn(CC)c3)cc(C(=O)N3CCCC3)c2c1 +CCOC(=O)CN(C(=O)C1CC2C=CC1C2)C1CC1 +CCN(CCn1cccn1)C(=O)c1ncccc1OC +O=C(NC1CC1)NC1CCN(C(=O)CCc2ccccc2)C1 +N#CCCN(C(=O)Cc1ccc(Cl)c(Cl)c1)C1CC1 +Cc1nc(C)n(CC(=O)NCCCOC2CCCCC2)n1 +Cc1n[nH]c(SCC(=O)NCc2ccccc2)nc1=O +Cn1cnnc1-c1ccc(NC(=O)CCC2CCCC2)cc1 +CCOC(=O)c1c(C2CC2)csc1NC(C)=O +CCOc1ccnc(N2CCN(C(=O)Cn3cnnn3)CC2)n1 +Cc1ccccc1C(=O)OC(C)C(=O)Nc1ccccc1 +C=CCn1cc(CN2CCN(c3ncc(C#N)c(N)n3)CC2)c(C)n1 +Cc1noc(C(C)OC(=O)c2cc(C(C)(C)C)on2)n1 +CCc1c(C)sc2ncn3nc(-c4ccn(CC)n4)nc3c12 +CC(C)(C)CNC(=O)c1nccn1-c1ccccc1C#N +O=C(Cc1c[nH]c2ccccc12)Nc1cccc(Oc2cnccn2)c1 +CN(C)C(=O)COc1ccc(NC(=O)NCc2ccccn2)cc1 +Cc1cc(S(=O)(=O)N2CCCC2)cnc1NC(C)C +CCOC(=O)c1sc2ncn3nc(-c4cc[nH]n4)nc3c2c1C +CCN(CC)C(=O)Cn1c(=O)c(C#N)cn(C2CC2)c1=O +COc1ccc(C(=O)NCCNC(=O)N(C)Cc2ccncc2)cc1 +CCN(CC)C(=O)c1cc(NCC2CCC2)ccn1 +CCOC(=O)c1cn(Cc2c(CC)noc2C)nc1C(F)(F)F +COc1ccc(OC)c(-n2cnnc2-c2cn[nH]c2)c1 +CCCNC(=O)Nc1ccc(-n2cccn2)c(F)c1 +COc1ccccc1OCCNC(=O)Cc1coc2cc(C)ccc12 +COc1cc2c(cc1OC(F)F)C(C(C)(C)O)NCC2 +CC(=O)c1ccc(Cl)c(NC(=O)C(C)(C)C)c1 +COCC(C)NS(=O)(=O)N(C)Cc1ccccc1 +CC(=O)N1CCc2cc(-c3csc(C)n3)ccc21 +O=C(CSc1ncccc1Cl)NCc1ccco1 +CNC(=O)c1c(C)nc(N)nc1Cc1ccccc1 +CCc1cc(CN(C)C(=O)CN2C(=O)CCC2C)on1 +O=C(Cc1ccccc1)Nc1nnc(-c2cc3ccccc3o2)o1 +Cc1nc(S(=O)(=O)N2CCC(C)CC2)c(C#N)c(C)c1Cl +Cn1ccc(C(=O)N(CCc2ccccc2)Cc2ccncc2)cc1=O +CC(C)(CNC(=O)Cc1ccccc1Cl)c1ccncc1 +NS(=O)(=O)c1ccc(NC(=O)N2CCC(O)CC2)cc1 +O=c1[nH]c2cc(F)c(Br)cc2c(=O)o1 +CCOc1ccc(CC(=O)Nc2sccc2C(=O)NC)cc1 +CC(CO)CNC(=O)NC(c1ccc(Cl)cc1)C1CC1 +CC(NC(=O)N1CCOCC1)c1ccc2c(c1)OCCO2 +O=C(NCCc1nnc2ccccn12)NCC1CCCC1 +COc1ccc(OC)c(-c2ccc(SCc3ccncc3)nn2)c1 +CC1CC1C(=O)N1CCN(S(=O)(=O)c2cccs2)CC1 +CC(C)C(C)(C#N)NC(=O)CN1CCN(C(=O)C2CCCO2)CC1 +CCCNC(=O)c1cccc(CNC(=O)NC2CCCC2)c1 +O=C(Nc1cnn(Cc2cccnc2)c1)c1ccc(O)c(Cl)c1 +Cc1cc(C(=O)NCC(O)c2ccc(Cl)cc2)no1 +Cc1cc(=O)c(C(=O)NCC2COCCO2)nn1-c1ccccc1 +Nn1c(Cc2cccc3ccccc23)nnc1SC1CCOC1=O +O=C(NCCn1cnc(-c2ccc(F)cc2)cc1=O)C1CCCO1 +Cc1cccc(OCCCC(=O)Nc2ccc(N)cc2C)c1 +CCOC(=O)C(NC)c1ccc(Cl)c(Cl)c1 +CC(C)CCNC(=O)c1cc(S(C)(=O)=O)c(Cl)cc1Cl +CC(O)CC(C)(C)CNC(=O)NCC1(c2ccc(F)cc2F)CC1 +O=C(CCn1nnc2ccccc21)N1CCCCC1c1ccccn1 +Cc1cncnc1C1CCN(S(=O)(=O)N2CCOCC2)CC1 +CC(=O)c1ccc(NC(=O)c2cc3c([nH]c2=O)CCCC3)cc1C +Cc1sc(=O)n(CC(=O)NCCCCN2CCOCC2)c1C +COc1ccc(NC(=O)N(C)CCCOc2ccccc2)cn1 +CNc1nnc(-c2cc(C)nc3c(OC)cccc23)s1 +Cc1cc(NC(=O)C(c2ccccc2)N2CCCCC2)no1 +COc1ccc(Cl)cc1C(=O)NC1CCN(S(C)(=O)=O)CC1 +COc1ccc(NC(=O)c2ccncc2)cc1-n1cnnn1 +O=C(Nc1cnn(-c2ccccc2Br)c1)c1cnccn1 +Cc1cc(C)cc(N(C)C(=O)CSc2ncn[nH]2)c1 +CN1C(=O)Cc2cc(NC(=O)NCc3ccccc3)ccc21 +Cc1cc(NC(=O)C(C)(C)c2ccc(Cl)cc2)n(C)n1 +CC(C)N(C)S(=O)(=O)NCc1cn(-c2ccccc2)nn1 +CN1CCc2c(cccc2NC(=O)c2cnccn2)C1 +CCOC(=O)c1csc(NC(=O)c2cc(OC)cc(OC)c2)n1 +COc1cc(NC(=O)C2CCC2)c(OC)cc1Cl +CC(C)(C)CC(=O)Nc1cccc(S(=O)(=O)NC(C)(C)C)c1 +CC(C)COC(=O)Nc1ccccc1C(=O)N1CCOCC1 +CCCN(C)c1ccc(C(=O)Nc2cc[nH]n2)cc1 +CCCS(=O)(=O)N(Cc1cnc2ccccn12)C1CC1 +Cc1ccc(C)c(CNC(=O)c2cc3ccccc3oc2=O)c1 +CC(C)n1cc(NC(=O)c2cc(-c3ccccc3)on2)cn1 +O=C1Nc2cc(Br)c(Br)cc2C1=O +Cc1cccc(OCC(O)CNC(=O)NC(C)c2ccncc2)c1 +Nc1cccc(CCC(=O)N2CCN(c3ccc(F)cc3)CC2)c1 +Cc1noc(C)c1CC(=O)NCc1cccc(C#N)c1 +Cn1cc(C(=O)Nc2ccncc2)c2ccccc21 +COCC(O)CN(C)C(=O)Cc1ccccc1N +O=S(=O)(CCn1ccnc1-c1cnccn1)c1ccccc1 +COc1cc(CC2(C(C)=O)CC2)cc(OC)c1OC +COc1ccccc1-c1c(C)nn2c(-n3ccnc3)cc(C)nc12 +COc1c(F)cc(F)cc1-c1ccccc1OC(C)C(N)=O +C=C(C)Cn1c(NCCCn2ccnc2)nc2c1c(=O)[nH]c(=O)n2C +CC1CC(=O)N(C)c2cc(S(=O)(=O)NCCO)ccc2O1 +CCOc1cc(NCc2ccncc2)nc(C(C)(C)C)n1 +CC(C)NC(=O)C(NC(=O)c1cccc2ccoc12)c1ccccc1 +Cc1csc(NC(=O)CSc2nnc(C(C)C)n2C)n1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)OCCc1cccs1 +CN(CCOc1cccc(Cl)c1)c1ncnc2c1cnn2C +CCC(C)C(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +O=C(Cc1csc(N2CCCC2=O)n1)OC1CCCC1 +Cc1cccc(NC(=O)CCNC(=O)Nc2ccccc2)n1 +Cc1nc(N)c2cnn(CCc3ccccc3)c2n1 +CN1CC(NC(=O)c2ccc(Br)cc2O)CCC1=O +Cc1ccc(Cl)c2c1CCNC2c1ccncc1F +Cc1cc(C)n(Cc2cccc(C(=O)NC(C)Cc3ccccn3)c2)n1 +N#Cc1ccc(C(F)(F)F)nc1NCC1(C(N)=O)CCCC1 +OC(C#CCn1cncn1)(c1ccccc1)c1ccccc1 +CCCc1n[nH]c(SCc2nnc(C3CCCO3)o2)n1 +CC(=O)c1cccc(Nc2ncc(Br)cn2)c1 +CC(O)CN(C(=O)NCc1csc2ccccc12)C(C)C +Cc1cccc(C2(C(=O)Nc3ccn(CCc4ccncc4)n3)CC2)c1 +CC1CN(C(=O)CNC(=O)c2ccc3c(c2)OCO3)CCO1 +N#Cc1c(Br)cccc1N1CCCC1 +CC(=O)NCCNS(=O)(=O)c1ccc(C)cc1C +CCn1ccc(=O)n(Cc2ccc(Cl)cc2)c1=O +CCOC(=O)C1CCCN(c2ncnc3c(C)nn(CC)c23)C1 +COCc1cc(C(=O)NCCOc2ccccc2)ccc1F +COC(=O)C(C)n1c(CC#N)nc2ccc(F)c(F)c21 +CCC(=O)N1CCCC(C(=O)Nc2ccc(OC(F)F)c(F)c2)C1 +CNC(=O)c1cc(S(=O)(=O)NC(C)c2ccccc2)ccc1OC +CCn1cc(C2CCN(C(=O)Nc3ccc4c(c3)COC4)CC2)cn1 +O=C(NCc1cccs1)c1ccc(Br)cc1 +O=C1N(CC2CC2)C(c2cscn2)NC12CCCC2 +Cc1cc(C)c(O)c(C(=O)NC2c3ccccc3CC2O)c1 +Cc1ccc(CC(=O)N2CCN(CCO)CC2)s1 +CCOCC1CCN(C(=O)Cc2ccc(F)cc2F)CC1 +Cn1cc(C(=O)Nc2cnc(C3CC3)nc2)c(C(C)(C)C)n1 +CC(NC(=O)C1CC(=O)N(C(C)C)C1)c1ccccc1C(F)(F)F +Cc1nc(C2CCCN(C(=O)C3CC3c3ccc(F)cc3)C2)no1 +Cn1cc(C(=O)N2CCOC(C)(C(N)=O)C2)ccc1=O +CC(CN1CCOC1=O)NC(=O)c1ccc(F)c(Br)c1 +CCN(Cc1ccc(OC)c(F)c1)C(=O)c1ccc(C)[nH]c1=O +COc1cc(Cl)c(NC(=O)c2ccc3ccccc3n2)cc1OC +OC(CNCc1c[nH]nc1-c1cccnc1)c1ccc(F)cc1 +COCc1nc2cc(-c3ccc(OC)cc3)sc2c(=O)[nH]1 +O=C(Nc1cccc(OCC(=O)N2CCCCCC2)c1)c1ccco1 +CC(C)Cc1ncc(C(=O)N2CCCc3ccccc32)c(N)n1 +CCc1nc2c(cnn2C)c(=O)n1-c1ccc(C)cc1 +CC(=O)c1ccc(NC(=O)N(C)C(C)c2ccco2)cc1C +CC(=O)NCc1nnnn1-c1ccc(Cl)cc1 +CCOc1cc(C)ccc1NC(=O)c1cc(NC(C)=O)ccc1F +COc1ccc(C(O)c2ccc3[nH]c(=O)[nH]c3c2)cc1 +CC(C)NC(=O)Cn1ccc2ccc(N3CCCCC3)nc21 +COC(=O)COc1ccc(C(=O)NCc2ccccc2)cc1 +CCCc1ccc(C(C)NC(=O)c2cc(C)nc3ncnn23)cc1 +O=C(NCc1ccncc1)C1CCN(c2ncccn2)CC1 +COc1ccc(C(=O)CCC(=O)NC(C)c2cc(C)oc2C)cc1 +Cc1cnc(NC(=O)c2cnc3onc(C)c3c2)s1 +COC(=O)CNC(=O)C(Oc1ccc(Br)cc1)C(C)C +COc1cc2c(cc1OC)CN(S(C)(=O)=O)CC2 +CC(C)n1c(C(=O)N(CCO)Cc2ccccc2)cc2sccc21 +CC1CCN(C(=O)C2CCCN(c3cnc4nccnc4c3)C2)CC1 +CCOC(=O)c1n[nH]c2c1CCC2=Cc1ccccc1 +Cc1ccc2c(c1)N(CC(=O)NC(C)c1ccccc1)C(=O)CO2 +CCC(=O)N1CCc2cc(C(=O)NCc3ccnc(OC)c3)ccc21 +Cc1cc(C)n(-c2ccc(Cl)c(C(=O)OCc3nc(C)no3)n2)n1 +O=C(N1CCc2ccccc2C1)C1(c2cc(-c3ccco3)on2)CC1 +CC(O)c1ccc(NS(=O)(=O)c2cn[nH]c2)cc1 +CNC(=O)Oc1cc2oc(=O)sc2cc1Cl +Cc1ncc(C(=O)NCc2ccc3c(c2)OCO3)c(C)c1N +COc1c(C)cnc(CSc2nnc(-c3ccoc3C)n2C)c1C +C=CCN(Cc1cccc(C#N)c1)C(=O)c1ccc(-n2ccnn2)cc1 +O=C(CCc1ccco1)N1CCCCC1c1nccs1 +Nc1nonc1C(=O)NCCNC(=O)Nc1ccc(F)c(Cl)c1 +C=CCn1ncc(CN2C3CCC2c2cnc4cc(C)nn4c2C3)c1C +O=C(CCNC(=O)c1ccsc1)NCC(O)c1ccc(F)cc1 +Cc1cccc(C)c1OCC(=O)NCCc1c(O)n[nH]c1C +CCCC(=O)NCC(=O)NC1(C(=O)OC)CCCC1 +O=C(NCCO)c1cc(-c2ccn(CC3CC3)n2)n2ccccc12 +Cc1cc(C)n(CC(C)CNC(=O)CCc2c(C)n[nH]c2C)n1 +COc1ccc(C=Cc2nc(C(C)(C)OC)no2)cc1OC +CCn1cnnc1CNC(=O)NCCC(C)(C)C +CC(NC(=O)Cc1ccc[nH]1)c1nc(-c2ccncc2)cs1 +CCS(=O)(=O)NC(C)c1cc(OC)c(OC)cc1C +CCN1CC(C(=O)N(CCc2cccc(F)c2)C2CC2)CC1=O +COC(=O)Nc1ccc(S(=O)(=O)NCCc2ccsc2)cc1 +CC(NC(=O)c1cnn2cccnc12)c1ccccn1 +CNC(=O)c1nc(-c2ccccc2F)n2c1CCCCC2 +Cc1occc1C(=O)Nc1ccc2c(c1)CCCN2 +Cc1nc(CN(C)S(=O)(=O)c2ccc(F)c(F)c2)cs1 +CCC(CC)C(=O)Nc1ccc(C2OCC(=O)N(C)C2CO)cc1 +Cc1cc(OC(=O)Cn2cnc3c(cnn3C)c2=O)ccc1C(C)C +CCc1onc(C)c1NC(=O)Nc1ccc2c(c1)N(C)C(=O)CO2 +CC1c2ccsc2CCN1C(=O)c1ccc(Cl)cc1F +CNC(=O)c1ccc(NC(=O)c2cccnc2OCC(F)F)cc1 +CCOC(=O)C1(NC(=O)C2CCCC2)Cc2ccccc2C1 +CCc1nc(CC(=O)Nc2cccc(-c3nncn3C)c2)cs1 +CCn1ccnc1S(=O)(=O)Cc1ccc(C#N)cc1 +CC(C)Cn1ncnc1CN1CCC(C(=O)c2ccc(O)cc2)CC1 +CC(C)C(Sc1nnnn1C(C)C)C(=O)N1CCCCC1C +Cc1ccc(-n2nnnc2-c2cccc(N)c2)cc1C +Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3ccncc3)CC2)cc1 +Cc1nc2cccc(F)c2n1Cc1ccc(N)nc1 +CCc1ccc(OCc2c(CO)nnn2C(C)C)cc1 +COc1ccc2c(c1)nc(C(F)(F)F)n2-c1cnc(N)cn1 +CC(CO)NC(=O)COc1ccc(C(C)(C)C)cc1 +CN(Cc1ccco1)C(=O)CSc1nc(C2CCCC2)n[nH]1 +COCCn1c(SCc2ccccc2)nc2c1c(=O)[nH]c(=O)n2C +Cc1ccc2ncc(C(=O)N3CCN(C(=O)C(C)(C)C)CC3)n2c1 +O=C(CSc1nc2ccccc2o1)NCc1ccccn1 +COc1cccc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)c1 +CCc1ccc(-c2nc3sc(C)nn3c2CO)cc1 +O=C(COc1ccccc1)NCCN1CCN(C(=O)C2CCC2)CC1 +CC(C)N(C)C(=O)NCc1cc(=O)[nH]c2ccccc12 +CC1CN2C(=O)Cc3c(S(=O)(=O)N4CCCC4)ccc(c32)S1 +Cc1ccc(C)c(Nc2nc(NCCO)nc3c2cnn3C)c1 +CC(NC(=O)NCc1ncn(C)n1)c1ccc(OCC2CC2)c(F)c1 +Cc1ccc(N(C)S(=O)(=O)c2ccc(-n3cccn3)cc2)cc1 +CC(C)(C)n1cc(C#N)cc1NC(=O)OCC(F)(F)F +O=C(CC1CCCO1)Nc1ccc(C(=O)N2CCCCCC2)cc1 +Fc1cccc(OCCOc2cccc(-n3cnnn3)c2)c1 +Cc1cccc(C(=O)N(CCC#N)CCc2ccccc2)c1 +N#Cc1ccccc1Cn1nc(-c2cccs2)oc1=O +CCN(CCC#N)C(=O)COc1ccc2ccccc2c1 +Cn1cc(CCCNS(=O)(=O)Cc2cccc(F)c2)cn1 +CC(C)(C)OC(=O)NCCNC(=O)Cc1c[nH]c2ccc(F)cc12 +CCn1nc(C)cc1-c1nn2c(Cc3c(C)noc3C)nnc2s1 +CCCNc1nnc(-c2cnc(C(C)C)s2)s1 +O=C1CCCN1Cc1nnc2n1CCN(C(=O)c1cnccn1)C2 +CCc1ccc(NC(=O)COc2ccc(CO)cc2)cc1 +COCC(C)NC(=O)c1ccc(-n2cnnn2)c(C)c1 +Cc1cc(C(=O)Oc2ccc3c(c2)OCCO3)c(C)s1 +Cn1cc(CCNC(=O)C2(C#N)CCCCC2)cn1 +CN(Cc1ccc2c(c1)OCO2)C(=O)C1CCN(C(=O)C2CC2)CC1 +O=C(CNC(=O)Cc1ccc(Cl)cc1)NCC(F)(F)F +CC(C)(C)OC(=O)N1CCN(c2cnc(N)cn2)CC1 +Cc1cnc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)cn1 +O=C(NCc1nnc2ccccn12)c1c(F)cccc1Cl +OCc1ccc2oc(CCc3ccccc3)nc2c1 +COc1ccc(-n2nc(C)nc2C(OC)c2ccccc2)cc1 +CC(Cc1ccco1)Nc1ncc(Br)cc1N +Cc1cc(=O)nc(-n2nc(C3CC3)cc2NC(=O)c2ccccc2)[nH]1 +CC(C)Oc1ccccc1NCc1noc(C2CC2)n1 +O=C(CCc1nc2ccccc2s1)Nc1nnc(C2CC2)s1 +O=C(NCCCO)Nc1cccc(-c2nnc3n2CCC3)c1 +C=CCNC(=O)C(N)c1cc(Cl)cc(Cl)c1 +CCCn1nnnc1COC(=O)c1ccc(C(N)=O)cc1 +O=C(NCCc1ccccn1)C1Cc2cc(Cl)ccc2O1 +Cc1nc2scc(-c3ccc4c(c3)NC(=O)CO4)n2c1N +Cc1cccnc1NC(=O)c1cccc(N2CCCC2=O)c1 +CCOC(=O)CN(C)S(=O)(=O)c1ccc(C)c(F)c1 +Cc1c(C(=O)NC2CCCC2)oc2c1C(=O)CC(C)(C)C2 +CC(Sc1nnc(C(F)(F)F)n1N)C(=O)NC1CCCCC1 +C#Cc1cccc(NC(=O)CN(C)C(=O)c2occc2C)c1 +Cc1ccc2[nH]nc(C(=O)NCCS(=O)(=O)c3ccccc3)c2c1 +COc1ccc(CC(=O)N(Cc2cccc(C)c2)C2CC2)cc1OC +O=C(CCNC(=O)c1cccs1)OC1CCCC1 +COc1cccc(C(=O)NCc2ccnc3ccccc23)c1F +OCC1CC1c1ccc(Cl)c(C(F)(F)F)c1 +CC(C)N(C)C(=O)NC1CC1c1c(F)cccc1F +CCCCNC(=O)C(C)Oc1ccc(C(C)O)cc1 +N#Cc1c(C2CCCC2)nn(-c2ccccn2)c1N +O=C(c1cnc(C2CCCO2)s1)N(CCO)CCc1ccccc1 +NC(=O)c1oc2ccccc2c1NC(=O)C1COc2ccccc2O1 +Nc1ccc(NC(=O)c2c(F)cccc2Cl)cc1F +C=C(C)CN1C(=O)C(C)(C)Oc2cc(CO)ccc21 +Cc1cccc(OC2CCN(C(=O)C(NC(N)=O)C(C)C)CC2)c1 +Cc1c(NC(=O)c2ccccc2)cccc1NC(=O)c1cnn(C)c1 +Cc1ccc(C(=O)NCCNC(=O)c2ccccc2)cc1 +CCOC(=O)Cc1csc(NC(=O)c2ccccc2SC)n1 +Cc1cccc(NC(=O)C2CC(O)CN2C(=O)OCC(C)C)c1 +Cc1c(CN2CCOC(Cc3ccccc3Cl)C2)cnn1C +CN(CC(=O)N1CCCC1)C(=O)c1cccc(F)c1 +Cc1c(-c2cnn(-c3ccccc3)c2)ccc2nc(N)nn12 +COc1ccnc(NC(=O)CNC(=O)c2ccc(C#N)cc2)c1 +O=C(CCC1CCCC1)N(Cc1ccncc1)C1CC1 +CCCC(C)CNc1ccc2[nH]c(=O)c(=O)[nH]c2c1 +O=C(CCC(=O)c1ccccc1)NCCc1cccs1 +CCCN(CC(F)F)C(=O)c1coc(-c2ccccc2)n1 +CC1Oc2ccccc2OC1C(=O)NCCN(C)c1ccccc1 +CCCC(=O)NCC1CCCN(C(=O)Cc2ccc(OC)cc2)C1 +O=C(Nc1cccc(N2CCCC2=O)c1)OCc1ccccc1 +Cc1noc(C2CCN(C(=O)NC3CCC(O)CC3)CC2)n1 +CCCc1nnc(SCc2cc(=O)n3c(C)csc3n2)[nH]1 +Cc1nnnn1-c1cc(NC(=O)CCc2ccco2)ccc1F +CCOC(=O)c1c(NC(=O)c2cc(C)no2)sc2c1CCC2 +CCn1ccnc1N1CCN(C(=O)COc2ccc(Cl)cc2)CC1 +CCOC(=O)c1[nH]c2ccc(C)cc2c1NC(=O)CC +CCOCCNC(=O)c1ccc(N2CCOCC2)cc1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)N1CCCCCC1 +O=C(CC1CCCCC1)Nc1nc(-c2ccco2)n[nH]1 +O=C(Nc1c(-c2ccccc2)nc2ccccn12)c1ccco1 +CNC(=O)NCC(=O)NC(C)c1c(Cl)ccc(F)c1Cl +CCC(C)NC(=O)C(C)NC(=O)NC(C)c1ccc(C)c(F)c1 +CCOc1ccc(COC(=O)c2cccc(N)c2)cc1 +O=S(=O)(NC1CCN(c2ccccc2)CC1)N1CCOCC1 +COC(C)c1cccc(NC(=O)N(C)C(C)CC#N)c1 +COC(=O)c1cccc(CCNC(=O)NCc2ncccc2F)c1 +COCCCCNc1ccccc1C(=O)N1CC(C)CC(C)C1 +CC(=O)Nc1ccc(F)c(NC(=O)OC(C)(C)C)c1 +Clc1ccc2cccnc2c1CSc1ncn[nH]1 +CC(=O)c1nnn(CC(=O)Nc2ccc(F)c(Cl)c2)c1C +CC(C)n1c(C2CCCN(C(=O)Cc3ccccc3)C2)nn(C)c1=O +Cc1n[nH]c(-c2cccc(CNC(=O)c3cccc4cn[nH]c34)c2)n1 +Cc1occc1C(=O)N(C)c1nc2ccccc2o1 +NC(=O)C1CCCN1C(=O)CCOc1ccccc1-c1ccccc1 +Cc1nc(C2CC2)ncc1C(=O)N1CC(C)C(O)(C(C)C)C1 +CCOC(=O)CN1C(=O)C(C)Sc2ccc(N)cc21 +COCc1cccc(NC(=O)Cc2cccc(Cl)c2)c1 +CCOC(=O)c1cn(Cc2cccc(C)c2)c2ccccc2c1=O +O=C1CSc2ccc(NC(=O)Nc3ccncc3)cc2N1 +OCCN1CCN(Cc2c[nH]nc2-c2cccc3ccccc23)CC1 +Cn1ccsc1=NC(=O)CC(NC(N)=O)c1cccs1 +Cc1cccc(CS(=O)(=O)N(C)c2nccs2)c1 +CC(Oc1ccccc1)C(=O)Nc1ccc2c(c1)COC2 +Cc1cc(C(=O)NC(C)C(=O)N2CCCCC2)n(C)n1 +CC(=O)c1nnn(CC(=O)Nc2c(C)cccc2C(C)C)c1C +COC(=O)c1c(NC(=O)c2c(OC)cccc2OC)sc(C)c1C +COCc1ccccc1C(=O)OCCc1ccccc1 +Cc1ccnc(C(NS(=O)(=O)CC(C)c2ccccc2)C2CC2)n1 +Cc1cnc(C(=O)NCCC23CC4CC(CC(C4)C2)C3)cn1 +NC(=O)c1c(Cl)cccc1NC(=O)c1ccnc(OC2CCC2)c1 +COC(=O)c1cc(-c2ccc(F)cc2)nc2onc(C)c12 +Fc1cc(Cl)cc2c1CCNC2c1nccs1 +CCS(=O)(=O)NCCSc1nnc(C2CC2)n1C +Cc1ccc(C(C)NC(=O)c2sc(-c3ncccn3)nc2C)o1 +O=S(=O)(NCC1(c2ccccc2)CC1)c1ccc2c(c1)OCCO2 +CC(C)Cc1nnc2sc(NC(=O)c3ccccc3)nn12 +C#CCN1C(=O)C(Cc2cc(C)ccc2C)Oc2cc(N)ccc21 +FC(F)CN1CCN(Cc2c[nH]nc2-c2cccc(Cl)c2)CC1 +CC1CN(C(=O)NCCCSc2ccccc2)CCO1 +CC(C)N(Cc1nnc(-c2ccccc2)o1)C(=O)c1cccc(C#N)c1 +O=C(NC1CCCc2ccccc21)c1n[nH]c2ccccc12 +CC(C)CC(CNC(=O)c1cccn1C)N1CCOCC1 +CN(C)c1cccc(C(=O)Nc2nc3c(s2)CCCC3)c1 +COc1ccc(C)cc1NC(=O)c1cc(OC)c(OC)c(OC)c1 +Cc1ccc(C)c(NC(=O)CSc2nc3c(=O)[nH]cnc3n2C)c1 +COC(Cc1ccc2c(c1)CC(=O)N2)(OC)OC +OCc1nc2cc(Cc3ccc4nc(CO)[nH]c4c3)ccc2[nH]1 +CNC(=O)NCC(=O)NC(C#N)c1ccc(Cl)cc1 +COc1cc(-c2c(CO)nnn2CC#N)cc(OC)c1OC +C=CCN(CCc1ccncc1)Cc1ccccc1 +CC1CCCN(C(=O)Nc2cc(Br)ccc2F)C1CO +CC(C)N(CCC#N)C(=O)CCOc1ccccc1 +COc1ccc(F)cc1NC(=O)N(C1CC1)C(C)C1CC1 +OC1CCN(c2ccnc(NCCCc3nc4ccccc4[nH]3)n2)C1 +COCc1nc2cc(C)cnc2n1CCOc1ccc(N)c(C)c1 +COC(=O)c1occc1CN1CCN(C(=O)c2cc(C)oc2C)CC1 +CCOC(=O)c1cc(C)ccc1S(=O)(=O)C(C)C +COCCNc1ncnc(Nc2ccc(C(F)(F)F)cc2)c1N +COc1ccccc1CCC(=O)Nc1nnc(-c2ccccn2)[nH]1 +CCOCc1ccccc1CNC(=O)c1cc(Cl)ccn1 +O=C(Nc1cccnc1N1CCCCC1)c1ccc(-n2cnnn2)cc1 +CC(C)(CNC(=O)CCc1ccccc1O)c1ccncc1 +CN(Cc1nc2ccccc2c(=O)[nH]1)Cc1cccc2cccnc12 +CCCNc1nnc(Sc2cc(C)nc(C)n2)s1 +CC1(C)Cc2cccc(CN3CCOC(C(F)(F)F)C3)c2O1 +O=C(CNC(=O)c1ccccc1Br)Nc1ccccc1O +Cc1ccc(OCCN2C(=O)C(C)(C)Oc3ccc(N)cc32)cc1 +COC(=O)N1CCC(NC(=O)c2cc3ccccc3s2)CC1 +O=c1[nH]c(Cc2ccc(OCCO)cc2)nc2ccc(Cl)cc12 +O=C(Nc1ccc(F)cc1)C1CCCN1C(=O)c1ccccc1F +COc1ccc(Nc2ncnc(-n3nc(C)cc3C)c2N)cc1 +Cc1ccc(-c2nn(C)c(=O)c3ccccc23)c(O)c1 +COc1ccc(-c2nnc(SCC(=O)N(C)C(C)C)o2)cc1 +O=C(c1c(F)cccc1F)N1CCC(c2nnc3n2CCC3)CC1 +Cc1cc(C)nc(C(C#N)C(=O)Cc2ccc(OC(F)F)cc2)n1 +CC1CCCC1NC(=O)NCC(=O)Nc1ccc(F)c(F)c1F +Cc1ccc(C)c(-n2nnc(-c3ccncc3)c2N)c1 +CCC(CNC(=O)c1ccc(C(N)=O)cc1)c1ccccc1 +Cc1cc(OCC(=O)OCC2CCC(=O)N2)ccc1C(C)C +COCCN1CC(C(=O)NC(C)c2ccc(C)o2)CC1=O +CCOC(=O)N1CCC(Oc2nncc3ccccc23)CC1 +CC(C)CC(NC(=O)OC(C)(C)C)C(=O)N(C)C +CCCc1nc(CN2c3ccccc3CC2C)no1 +Cc1cc(C)n(Cc2ccc(C(=O)Nc3ncccn3)cc2)n1 +Cn1cnc(S(=O)(=O)NCC(=O)NCC2CCC(C)(C)CC2)c1 +CC(C)C(=O)Nc1ccc(OS(C)(=O)=O)cc1 +Cc1cccc(NC(=O)CN(C)C(=O)c2ccc3c(c2)nnn3C)c1 +Cc1csc(NC(=O)c2cc3c(nc2N)CCCC3)n1 +CC1CN(C(=O)CNC(=O)c2cccc(Cl)c2)c2ccccc21 +COc1ccccc1NC(C)c1ccc2c(c1)OCCO2 +CCC(CC)c1nnc(NC(=O)CCc2ccsc2)s1 +Cn1ccsc1=NC(=O)Cc1cccc(F)c1 +CCNC(=O)CN(C)C(=O)C1C2CC3CC(C2)CC1C3 +O=c1ccc(C2NCCc3ccc4ccccc4c32)n[nH]1 +CCC(C)NC(=O)CCn1nc(-c2ccccc2)ccc1=O +COc1ccc(CC2NCCc3c2ccc(F)c3O)cc1 +Cc1c(C(N)=O)sc2nc(-c3ccc(Cl)cc3)[nH]c(=O)c12 +CC(=O)Nc1ccc2c(c1)sc(=NC(=O)c1cccs1)n2C +CCCOc1ccccc1OCc1nc(N)nc(N(C)C)n1 +Cc1noc(CCNC(=O)NCc2ccc(-c3ccn[nH]3)cc2)n1 +CC(C)(C#N)C(=O)Nc1cc2c(cc1Cl)OCCO2 +NC(=O)c1c(NC(=O)c2ccc(Cl)cc2)sc2c1CCCC2 +CCOc1cc(NS(=O)(=O)c2ccccc2)ccc1OC +COc1ccc(NC(=O)CSc2nnc(C)s2)cc1OC +COCC(=O)N1CCC(c2cc(-c3ccc(F)cc3)n[nH]2)C1 +CCc1ccc(NC(=O)Cn2c(C)nc3ccccc3c2=O)cc1 +Fc1ccc(CNc2cnn(CC(F)(F)F)c2)cc1Cl +CCCNC(=O)CNC(=O)c1cccc(OC)c1O +Cc1ccc(F)cc1NC(=O)CNC(=O)C1CCCCC1 +O=C(NCC1CCCO1)c1ccc(F)cc1Cl +CNC(=O)C1CCCCN1C(=O)CCc1c(C)nc2ncnn2c1C +NC(=O)c1nc(-c2ccccc2)oc1Oc1ccccc1 +CCC(NC(=O)Nc1ccc(F)cc1)c1nnc2n1CCCCC2 +Cc1ccc(-n2ccc3c(nnc4nc(C)nn43)c2=O)c(C)c1 +CCOc1ccccc1NC(=O)CCCN1CCOC1=O +CCOc1cc(NC(=O)NC2CCN(c3cnn(C)c3)C2)ccc1C +CC(O)(CNS(=O)(=O)c1cccc2ccccc12)c1ccco1 +COc1cc(N2Cc3ccccc3C2=O)c(OC)cc1Cl +CCc1cc2c(NCc3cnn(C)c3)ncnc2s1 +CCOC(=O)CNC(=O)NC(C)c1ccncc1 +CN1CCCn2c(nc(CNC(=O)c3cnn(C)c3)cc2=O)C1 +CCC(=O)NC(Nc1ccccn1)(C(F)(F)F)C(F)(F)F +COc1ccc(NC(=O)C(O)c2ccc(C)cc2)cc1Cl +O=C(NC1(c2ccc(Cl)cc2)CC1)c1csnn1 +CCC1C(=O)NCCN1S(=O)(=O)N1CCCC1c1ccco1 +COCC(=O)Nc1ccc(NC(=O)Cc2ccccc2)cc1 +COc1ccc(F)cc1C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +Cc1ccc(Cc2sc(NC(=O)CCn3cncn3)nc2C)cc1 +Cc1noc(C2COCC3CN(S(=O)(=O)N(C)C)CC32)n1 +COc1ccc2c(c1)CN(C(=O)c1cn(C)nc1C(C)(C)C)CC2 +Cc1cc(NC(=O)CN(C)C(=O)COCC2CC2)no1 +NC(=O)N1CC(NC(=O)c2cnccn2)C2OCCCC21 +Cc1cc(NC(=O)CCCNC(=O)c2ccco2)no1 +O=C(COc1cc(Cl)ccc1Cl)NCCc1ccccn1 +CCOC(=O)C1CCCN(C(=O)CSc2ncc3ccccn23)C1 +CCCC(=O)NCC(=O)c1cc(C)c(OCC)cc1C +CN(Cc1cccc(C#N)c1)C(=O)Cn1cc(C(F)(F)F)ccc1=O +Cc1cc(NC(C)c2ccc3ccccc3c2)n2ncnc2n1 +CC1(CNC(=O)c2cnc(C3CCCO3)s2)CCC1 +O=c1cc(CN2CCN(c3ccccc3)CC2)n(C2CC2)cc1O +CC(Sc1ccc(Cl)cc1)C(=O)NCc1ccncc1 +NC(=O)c1ccc(NCCCc2ccc(O)cc2)cc1 +Cc1noc(CN(C)C(=O)c2cccc(Cn3cccn3)c2)n1 +COc1ccc(CC(=O)NC(C#N)c2ccncc2)cc1OC +COc1ccc(CC(=O)N2CCn3c(nnc3C3CC3)C2)cc1 +Nc1ccc(-c2ccc(NC3CCCC3)nn2)cn1 +O=C(C1CC1c1cccnc1)N1CCCC(n2cccn2)C1 +CCOC(=O)c1ccc(CNC(=O)C2(c3ccccc3)CC2)o1 +CC(C)(C)OC(=O)CS(=O)(=O)c1ccccc1N +Cc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)CS3)c(O)c1 +COc1ccc(OCCn2c(=O)c(C#N)c3n(c2=O)CCC3)cc1 +CCOc1cccc(NC(=O)N(C)CCCOC)c1 +CCC(C)(C)C1CCC(NC(=O)NC2CC2)CC1 +COc1ccc(-c2cn3cccnc3n2)cc1NC(=O)C1CCCC1 +Cc1cc2nc(Nc3ncc(O)[nH]3)nc(C)c2cc1C +CC(C)c1c(C2CCN(C(=O)NCc3ccco3)CC2)noc1N +CC(C)c1cc(C(=O)C(C#N)c2nc3ccccc3[nH]2)n[nH]1 +COc1ccc(Cl)cc1S(=O)(=O)Nc1cccnc1 +CN(Cc1cnn(C)c1)C(=O)Nc1cnc2ccccc2c1 +CC(C)CC(=O)Nc1ccc(NC2CCCCNC2=O)cc1 +Cc1nnc(CN(C(=O)c2ccn(C3CCCC3)n2)C(C)(C)C)o1 +COc1ccc(C2Cc3ccccc3C(O)O2)cc1 +CCOc1cccc(C(=O)Nc2c(C)cc(N)cc2CC)c1 +CC(C)Cc1noc(CSc2nnc(-c3ccccc3)n2N)n1 +O=C(c1cc2ccccc2c(=O)[nH]1)N1CCC(Nc2cccnc2)CC1 +CCc1cc2c(=O)[nH]c(CCn3cnc4ccccc43)nc2s1 +Cc1cccc(NC(=O)CCNC(=O)Cc2ccc(F)cc2F)n1 +COCc1nn2cc(-c3cccc(OC)c3)nc2s1 +CSc1cnc(S(N)(=O)=O)c(OC2CC2)c1 +Cc1cccc(CN2CCN(c3ncc[nH]c3=O)CC2)n1 +CCC1CCc2sc(C(=O)N3CCOCC3)cc2C1 +CC(Oc1cccc(-c2cccc(CN3CCOCC3)c2)c1)C(N)=O +COc1ccc(CC(=O)NC(C#N)c2ccco2)cc1OC +Brc1cccc(Cc2nccn2CC2CCCO2)c1 +O=C(Nc1cccc(Cl)c1Oc1cccnc1)c1ccncc1F +CCOC(=O)Nc1ccc(NC(=O)c2cn3cccnc3n2)cc1 +Cc1ccc(NC(=O)NCC(O)C(C)(C)C)cc1S(C)(=O)=O +Nc1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +O=C(c1ccc2ccccc2c1)N1Cc2cncnc2C1 +Cc1nc(N(C)C)sc1CN(C)Cc1ccccn1 +COC(=O)c1ccn(COc2ccccc2Cl)n1 +Nc1ccc(C(=O)CSc2ccccc2)cc1N +COc1ccc(F)cc1NC(=O)C1(C#N)CCCC1 +CCOCC(=O)Nc1ccc2c(c1)N(C(C)=O)CCC2 +CC(=O)c1c[nH]c(C(=O)NCCCc2c[nH]c3ccccc23)c1 +COc1ccc(Br)cc1S(=O)(=O)NC(C)C +COc1cccc(CNC(=O)c2ccc3cccc(O)c3n2)c1 +O=C(OCc1ccc2c(c1)OCO2)C1COc2ccccc21 +COc1ccc(C(=O)N2CCN(c3ccc(F)cc3)CC2)nn1 +COc1ccc(SCC(=O)c2ccc(OC)c(OC)c2)cc1 +CS(=O)(=O)N1CC(NC(=O)c2cscn2)C2OCCCC21 +CC(C)Cc1noc(C2(c3cccc(F)c3)CCOCC2)n1 +CN(C(=O)COc1ccccc1)c1nnc(-c2cccnc2)s1 +CC(=O)c1sc(NC2CC3CCC2C3)nc1C +Cc1ccc(C)c(CC(=O)OCCn2cncn2)c1 +CC(=O)c1ccc(NC(=O)Nc2ncccc2C)cc1 +CNc1nc(CNC(=O)Nc2cccc(CC(F)(F)F)c2)cs1 +Cc1nnc(COc2ccc(NC(=O)c3ccc4[nH]cnc4c3)cc2)o1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NCC(C)C)[nH]n1 +CC(C)(C)OC(=O)N1CC=C(c2ccccc2)CC1 +O=S(=O)(c1cccc2ccccc12)N1Cc2cncnc2C1 +CCOC(=O)Cc1nc(-c2ccc(C(F)(F)F)cc2)ns1 +CCCn1c(-c2ccc(OC)cc2)ccc(C(C)=O)c1=O +C=CCc1cc(C(=O)N2CCN(c3ccccc3)CC2)ccc1OC +O=C(COc1ccccc1F)N1CCc2ccccc21 +CC(C)N(C(=O)CCc1ccc2c(c1)OCCCO2)C1CCOCC1 +O=C(COc1ccc(Cl)cc1)NCC(O)Cc1ccccc1 +COc1ccc(CN(C(=O)CN2CCOCC2)C2CC2)cc1 +CCOC(=O)c1noc(C(=O)N2CCN(CC)CC2)c1N +O=C(NCCCOCC1CCOCC1)c1ccccn1 +CC(=O)Nc1ccc(NC(=O)C(C)OC(=O)C(C)C)cc1 +Cn1cc2c(NCc3ccnc(OC(C)(C)C)c3)ncnc2n1 +O=C(c1ccc(Cl)cc1N1CCCC1=O)N1CCCC1 +Cc1cc(Cl)ccc1NC(=O)c1cc(=O)[nH]c2ccccc12 +CCOc1ccccc1NC(=O)N1CCN(C(=O)c2ccco2)CC1 +CCCNC(=O)C1(NC(=O)Cc2ccc[nH]2)CCCCC1 +CC(C)Cn1nnnc1SCC(=O)c1ccccc1 +CCC(C(=O)c1ccc(OC)c(N)c1)N1CC(C)OC(C)C1 +Cc1nn(C)cc1CNC(=O)Nc1cccc(Cl)c1 +COc1ccc(C(=O)Nc2ccc(C(C)=O)cn2)c(F)c1 +Cn1c2c(c(=O)n3ncc(C(=O)NCc4ccccc4)c13)CNCC2 +Cn1ccc(NC(=O)c2cccc(NC(=O)NC3CC3)c2)n1 +N#Cc1ccc(CNC(=O)c2ccc(OCC3CCCO3)cc2)cc1 +CCOc1c(Cl)cc(C(=O)NC2CC(=O)N(C)C2)cc1OC +Cc1ccsc1CNC(=O)CC1NC(=O)c2ccccc21 +O=C(CC12CC3CC(CC(C3)C1)C2)NCCc1cccnc1 +CSc1ccc(OC2CCCCC2=O)cc1C +O=C(NCc1ccco1)c1c[nH]c2cc(Cl)ccc2c1=O +O=C(CCCSc1ccccc1)NCc1ccccn1 +CC(Nc1ncc(Cl)cn1)C(C)n1cncn1 +CC(NC(=O)NCCc1cccs1)C(=O)N1CCCCC1C +COc1ccc(C(C)NC(=O)Nc2nnc(C)s2)cc1OC +NC(=O)CCCNC(=O)Cc1ccc(-n2cccc2)cc1 +CCCCc1nnc2sc(-c3cc(OC)c(OC)c(OC)c3)nn12 +Cc1ccc(S(=O)(=O)NCC#Cc2ccc(F)cc2)cc1 +O=C(NCc1ccc(O)cc1)c1cccc(OCC2CCCO2)c1 +CCc1nnc(NC(=O)c2cn3ccc(C)cc3n2)s1 +COCc1ccccc1COC(=O)c1ccnn1C +Cc1cccc(C(=O)N2CCCC2)c1NC(=O)NC(C)CCCO +COc1ccc(C(=O)NCCCn2ccnc2)cc1OC +Cc1cnc(CNC(=O)Cc2cnc3c(C)cccn23)cn1 +O=C(COC(=O)c1ccccc1O)NCCc1ccccc1 +Cc1ccc(C(=O)Nc2cc(=O)n(C)c(=O)n2C)cc1C +CSc1nc(NCCO)c(C#N)c(-c2ccc(C)cc2)n1 +NS(=O)(=O)c1cccc(NC(=O)c2cccc(F)c2F)c1 +COc1ccc(CN2CCN(c3ccc(O)cc3)CC2)cc1F +NC(=O)NCCCOC(=O)Cc1c(F)cccc1F +COc1ccc(S(=O)(=O)NCc2cccnc2)cc1C(C)(C)C +CCOCC1CCCN(C(=O)c2cn(CC(C)C)c3ccccc23)C1 +CNC(=O)c1cccc(NC(=O)C(C)Sc2ccc(C)cc2)c1 +Cc1noc(CNC(=O)c2cc3ccccc3oc2=O)n1 +Cc1ccc(Cn2cccc(NC(=O)C3CCOCC3)c2=O)cc1 +O=C(NCc1cc(-c2ccc3c(c2)OCO3)on1)c1ccc(=O)[nH]c1 +Cc1ccc(C(=O)N(C)C(C)C(O)c2ccccc2)cc1 +O=C(c1cccs1)N1CCN(c2ccc(O)cc2)CC1 +Cc1ccccc1NC(=O)c1onc(-c2ccccc2C)c1N +O=C(NCC1CCCO1)C1CC(=O)N(c2ccc(F)c(Cl)c2)C1 +Cc1ccc(-n2ncc3c(=O)n(CC(=O)NC4CC4)cnc32)cc1 +CN(C)S(=O)(=O)Nc1ccccc1C#CCCO +CCCc1ccc(CNC(=O)c2nonc2N)cc1 +CC(=O)Nc1cccc(NC(=O)NCc2ccc(C)cc2)c1 +CC(C)COc1ccccc1NC(=O)NCCC(=O)N(C)C +COCCN(Cc1ccco1)C(=O)Cn1c(C)c(C)sc1=O +O=C(c1ccc2c(c1)CCCC2)N1CCN(c2ncccn2)CC1 +COc1cc(CC(=O)N2CC(C)C(=O)Nc3ccccc32)ccc1C +CC(C)C(NC(=O)C(C)n1cccn1)c1cccs1 +Cn1cc(CCC(=O)Nc2nc(C3CC3)cs2)cn1 +CCC(C)NC(=O)Cn1cnc2c(sc3nc(C)cc(C)c32)c1=O +CC(NS(=O)(=O)c1ccc(O)cc1)c1ccccc1 +CCOC(=O)C(N)c1cc(-c2cc[nH]n2)ccc1F +CN(Cc1ccccc1)C(=O)CC(C#N)c1cccc(F)c1 +COc1ccccc1CNC(=O)Cn1c(=O)n(C)c2ccccc21 +COc1ccc(OC)c(S(=O)(=O)Nc2ccc(C)c(O)c2C)c1 +C=CCSc1ccccc1NC(=O)Cc1c(C)noc1C +CCCCN(C)C(=O)c1snc(-c2ccc(F)cc2)c1N +CCN(C)c1ncnc2c1CCN(C(=O)c1ccncc1)CC2 +COc1ccccc1CC(=O)N(CCC(N)=O)c1ccccc1 +CNC(=O)C1CCN(C(C(=O)NC2CC2)c2ccc(F)cc2)CC1 +O=C(C1CCCCC1)N1CCC(c2nc(-c3ccccn3)no2)C1 +CC(Oc1ccccc1F)C(=O)Nc1cccnc1 +CC(C)N(C)C(=O)c1cc(-c2ccc3c(c2)OCO3)on1 +NS(=O)(=O)c1ccc2c(c1)CCN2Cc1cccc2c1OCCO2 +Cc1nc(NC(=O)c2cc(C3CC3)[nH]n2)sc1C +CC(CC#N)N(C)C(=O)Nc1cccc(NC(=O)c2ccoc2)c1 +Cc1cc(Br)ccc1NC(=O)C1CC(=O)N(C)C1 +CN(Cc1ccsc1)S(=O)(=O)c1ccc2c(c1)OCCCO2 +N#Cc1ccc(COCC2CCN(C(=O)c3ccsc3)CC2)cc1 +CCCOc1cc(C)ccc1NCc1noc(C)n1 +COc1cccc(C(=O)Nc2ccc3c(c2)COC3)c1OC +CCCOc1ccc(OC(=O)Cn2cnc3ccccc3c2=O)cc1 +COc1ccc(OCCSc2nnnn2C2CC2)cc1 +Cc1noc(C)c1C(C)CNC(=O)c1cn(C)nc1C(C)(C)C +Cc1ccccc1C1CC1C(=O)N(C)Cc1nnc2n1CCC2 +Cc1nnc(SCc2c(C(=O)NC3CC3)oc3ccccc23)s1 +CN(CCc1ccncc1)C(=O)COC1CCCC1 +C#CCOc1cccc(NC(=O)C2CCCN2C(=O)OC(C)(C)C)c1 +CCc1ccc(C2CN(C(=O)C3CC3)CCO2)cc1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)C(C)(C)C)c1C +CCC(O)c1ccc2c(c1)C(NC(=O)C(C)(C)C)CCC2 +Cc1c(NC(=O)c2csnn2)c(=O)n(-c2ccccc2)n1C +CNC(=O)CC(C)N(C)C(=O)c1ccc2nc(C)cn2c1 +CCOC(=O)c1cc(C)n(CC(=O)Nc2ccccc2OC)c1C +Cc1cc(C)c2c(n1)sc1c(NCc3ccco3)ncnc12 +CCOC(=O)CNC(=O)Cc1ccc(N2CCCC2=O)cc1 +CN(C)c1ccc(C(=O)NCC(=O)OCc2ccccc2)cc1 +Cc1cc(C)n(CCNC(=O)CCn2ncc3cc(Cl)ccc32)n1 +Cc1cc(C)n2nc(SCC(O)COc3ccccc3C)nc2n1 +CCc1ccc2nc(C)cc(C(=O)NCc3cnn4cccnc34)c2c1 +Cc1cccc(CS(=O)(=O)Nc2ccc3c(c2)C(=O)NCC3)c1 +O=C(Nc1cccc2cccnc12)NC1CCOC2(CCOC2)C1 +Cc1cc(C)c(CNC(=O)C2CC(=O)N(C3CCCC3)C2)c(=O)[nH]1 +O=C(NCc1ccncc1)c1c(-n2cccc2)sc2c1CCC2 +COC(=O)c1ccc(Cn2c(N)nc3cc(F)ccc32)cc1 +O=C1CC(C(=O)Nc2ccccn2)c2ccccc2N1 +CCCC1Cc2cc3c(cc2-c2c1c(=O)c2=O)OCO3 +COC(=O)Cn1c(=O)n(CC(C)C)c(=O)c2ccccc21 +Cc1ccc(N(CCC#N)CCC#N)c(Br)c1 +O=C(Nc1cccc(OC2CCCC2)c1)C1CCCN1C(=O)C1CC1 +CCC(C)N(Cc1ccncc1)C(=O)c1cc(F)c(F)cc1Cl +Cc1ccnn1CCNC(=O)CC(c1ccco1)C(C)C +COc1ccc(NC(=O)c2cnc(C(C)(C)C)s2)cc1NC(C)=O +N#CC1(N2CCCCC2)CCSc2ccccc21 +C=CCNc1nc(-c2ccc3c(c2)CCC(=O)N3)cs1 +Cc1ccc(C(=O)Nc2nc3ccc(Cl)cc3s2)cn1 +CCOCC1CCN(C(=O)NCCCc2c(C)noc2C)C1 +C#CCN1CCC(C(=O)Nc2ccn(-c3ncccc3Cl)n2)CC1 +CN(C)S(=O)(=O)NC1CCOC1c1ccc(Cl)cc1 +CC1=C(C(=O)OC(C)(C)C)C(c2cccs2)n2nnnc2N1 +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)NCCc1cccs1 +CC(C)Oc1ncc(C(=O)N2CCOC3CCCC32)cc1Cl +CC1CCC(NC(=O)c2cc(Br)c[nH]2)CC1 +COc1ccc(Cl)cc1N1CC(c2nc3ccccc3[nH]2)CC1=O +Fc1ccc(-n2cccn2)c(-c2nnc3ccccn23)c1 +CCN1CCn2c(nc3cc(C(=O)Nc4ccccc4)ccc32)C1=O +CC(C)Cn1c(SCC#N)nnc1N1CCOCC1 +O=C(Nc1ccc(NCc2ccc(F)cc2)cc1)C1CC1 +CCN(CC)C(=O)c1cccc(NC(=O)CNc2ccccc2C)c1 +N#Cc1cccc(CN2C(=O)COc3ccc(N)nc32)c1 +CN(C)C(=O)N1CCC(C(=O)N2CCCCC2)CC1 +CCCn1nnnc1NCc1ccc(OC)cc1OC +CC(C)N(CC(N)=O)C(=O)c1ccc(Cn2cccn2)cc1 +O=C(NCc1ccccn1)Nc1nnc(CC2CCCC2)s1 +N#CCCNC(=O)Cn1cnc2cc(Cl)ccc2c1=O +O=C(Oc1ccc(F)cc1)c1cccc(CN2CCCC2=O)c1 +Cc1cc(NC(=O)Cc2cc(-c3ccc(F)cc3)on2)no1 +Cc1cnc(C(=O)N2CCC3CC(c4nccs4)OC3C2)cn1 +COc1ccc(-c2cc(=O)n3c(nc4ccccc43)[nH]2)cc1OC +Cc1cccc(CCNC(=O)C2CC3CCC2O3)c1 +Cc1ccc(S(=O)(=O)CCCn2ccc(C)c(C#N)c2=O)cc1 +O=C1CCN(C(=O)Nc2ccccc2C(F)(F)F)CCN1 +CCc1nnc2n1CCN(C(=O)C1COc3ccccc3C1)C2 +CN(CC(=O)NCCc1cccc(F)c1)c1ncnc2[nH]cnc12 +O=C(CSc1nncs1)N1CCN(c2ccccc2)CC1 +CCN1CC(C(=O)N(CC)C(C)c2ccc(F)cc2)CC1=O +COCCNC(=O)CCNC(=O)Nc1cc(C)nn1C +CCn1c(SCC(=O)NCC(C)C)nnc1-c1ccccc1 +Cc1ccc(OCC#CCNC(=O)COc2ccc(Cl)cc2)cn1 +CCn1nc(C(=O)NC(C)c2cc(OC)c(OC)cc2F)ccc1=O +Cc1noc(CSc2nc3ccccc3c3nc(C)nn23)n1 +Cc1ccc2nc(CCC(=O)N3CCC4(CCCO4)CC3)[nH]c2c1C +Cc1nnc2n(N)c(=O)c(CC(=O)c3ccc(F)cc3)nn12 +Cc1cc(NCC(=O)NC(C)C(=O)N2CCCCC2)ccc1F +CC(C)(C)C(NC(=O)c1cccc(OCC(F)F)n1)C(N)=O +CC(=O)c1csc(NC(=O)c2csc(Cc3ccccc3)n2)n1 +CN(C)C(=O)c1ccccc1NCc1ccncn1 +CNC(=O)c1cccc(NC(=O)c2cccc(Oc3ccncc3)c2)c1 +Cn1cc(CC(=O)NCC2CCCO2)c2cccnc21 +O=C(NCc1ccccc1)c1ccc(NC(=O)c2cnccn2)cc1 +CC(C)n1nccc1NC(=O)CCc1ccccc1 +NC(=O)c1csc(C(=O)Nc2cnn(Cc3ccccc3)c2)c1 +NC(=O)c1cccc(NC(=O)CSc2ccc3c(c2)CCC3)c1 +O=C(COc1cccc(Cl)c1)Nc1cc(N2CCCC2)ncn1 +Cc1ccccc1OCCNC(=O)Cc1noc2ccccc12 +CCOC(=O)N1CCN(c2nnnn2-c2ccccc2)CC1 +CC(C(=O)NC1CCCC1)N(c1cccc(Cl)c1)S(C)(=O)=O +CCN(Cc1ccc(OC)cc1)S(=O)(=O)c1cccc(C(N)=O)c1 +CCN1CC(C(=O)Oc2ccc(F)cc2)CC1=O +COc1ccc(S(=O)(=O)N(C)C2CCCCC2O)cc1Cl +Cn1nc(C2CCN(C(=O)CC3CCCCC3)CC2)c2nccnc21 +Clc1ccc(CSc2nnnn2C2CC2)c(Cl)c1 +O=C(Nc1cc(-c2ccccc2)n[nH]1)c1ccc2c(c1)OCO2 +CC1CCCC(NC(=O)CCCNC(=O)c2ccsc2)C1C +COc1ccc(CCn2cc(N)cn2)cc1Br +COc1cccc(COc2nc3c(c(=O)n(C)c(=O)n3C)n2C)c1 +CN(CC(=O)Nc1cccc(F)c1)C(=O)c1ccc(=O)[nH]n1 +Cc1cc(C)n2nc(C)c(C(=O)N3CCCC(C(F)(F)F)C3)c2n1 +CS(=O)(=O)c1cccc(-c2cnc(=O)[nH]c2)c1 +COCCN1CC(C(=O)Nc2ccc(F)c(Cl)c2)CC1=O +Cc1oc(C)c(S(N)(=O)=O)c1C(=O)N1CCc2sccc2C1 +COCCNC(=O)c1sc(NC2CCCCC2)nc1C +COc1ccc(CC2CN(C(=O)c3ccnnc3)CCC2OC)cc1 +CC1CN(C(=O)C(C)NS(=O)(=O)c2ccccc2)CC(C)O1 +CCCC(NC(N)=O)C(=O)N1CC=C(c2ccccc2Cl)CC1 +O=C(CCc1nc(-c2ccoc2)no1)N1CCCc2cccc(O)c21 +CCCC1c2cccn2CCN1C(=O)NCCOC +CCc1nc2cc(NC(=O)c3ccc(C)c(NC(C)=O)c3)ccc2o1 +CCc1cc(CNC(=O)NC(C)COc2ccc(C)cc2)[nH]n1 +O=C(Nc1ccccc1O)c1coc(NC(=O)C2CCC2)n1 +COc1ccccc1OC(=O)c1ccc(-c2ccccc2)[nH]c1=O +Cc1nn(CCC(=O)N(C)Cc2cnn(C)c2)c(C)c1Cl +Cc1cccc(C(=O)Nc2ccnc3ccccc23)c1 +COc1ccnc(NC2CCc3cc(F)ccc32)n1 +CC(C)N1CCc2nc3sc(C(N)=O)c(N)c3cc2C1 +Cc1nc2ccccc2c(C)c1CC(=O)NC(C)c1ccco1 +Cc1cc(N)ccc1S(=O)(=O)N(C)C1CCCCC1 +Cc1nc(CNC(=O)CN2C(=O)CSc3ccccc32)n[nH]1 +N#CC(NCc1cccnc1)c1c(F)cccc1Cl +CCSc1ccc(C(=O)N(C)C(C)c2cccnc2)cn1 +CCn1nc(C)cc1-c1nn2c(-c3ccccc3)nnc2s1 +CN(C)c1ccc(C(=O)NCCc2ccco2)cc1 +Nc1ccc2c(c1)C(c1cc(F)c(F)cc1Cl)NCC2 +CCC1CCCN(C(=O)NC2CCCN(Cc3ccccc3)C2=O)C1 +CCOC(=O)C1CCCN(C(=O)c2oc3ccccc3c2C)C1 +Fc1ccc(Cn2nnc(-c3ccccc3)n2)cc1F +O=C(CCn1c(=O)oc2ccccc21)NC1CCc2c(F)cccc21 +COc1cc(-c2noc(C)n2)ccc1OCC(=O)c1ccc(C)cc1 +CC(=O)c1c(C(F)(F)F)nn(C(=O)c2ccccc2)c1C +CC1CN(C(=O)CCN2C(=O)C(C)(C)c3ccccc32)CC(C)O1 +C=CCSc1nc(N)c(NC(=O)c2ccc(F)c(F)c2)c(=O)[nH]1 +O=C(NC(C1CC1)C1CC1)C1CCN(C(=O)C2CC2)CC1 +O=C(Nc1cccc2c1OCCO2)c1cnc(-c2ccccc2)nc1 +Nc1nc(COC(=O)c2cccc(O)c2)nc(Nc2ccccc2)n1 +Clc1ccc(-n2ccnc2-c2cccnc2)nc1 +COCc1cc(=O)[nH]c(Nc2cc(F)c(F)c(F)c2)n1 +CCOC(=O)c1sc2nc(C)ccc2c1NC(=O)c1ccco1 +CC(=O)c1ccc(NC(=O)c2cccc(Oc3cnccn3)c2)cc1C +O=C(NCC(O)(c1ccccc1)C1CC1)Nc1ccc2c(c1)OCO2 +COc1ccc(CCN(C)C(=O)c2c(C)noc2C)cc1OC +COc1ccc(OC)c(-c2c(CC(C)C)noc2N)c1 +CCCN(CC(=O)NC)C(=O)c1ccc(=O)[nH]c1 +Cc1ncc(C(=O)NCCc2ccc(F)cc2)c(N)n1 +CN1C(=O)COCC1C(O)c1ccc(NC(=O)c2ccccc2)cc1 +CC(C)N(CC(N)=O)C(=O)c1ccc2c(c1)OCCO2 +O=C(Cn1cnc2ccccc2c1=O)Oc1cccc(C(F)(F)F)c1 +Cc1cccc(C(=O)Nc2ccc(C(=O)NCC(C)C)cc2)n1 +Nc1cccc2c1nc(-c1cccs1)n2CCCO +CCCCN(C)c1ncnc(Nc2ccc(C(C)=O)cc2)c1N +CCOC(=O)c1ccc(N2CCCC(C(=O)NC)C2)nc1 +COc1ccc2c(c1)CCNC2C(CO)c1ccccc1 +CCc1nc(CC(=O)NCc2cc(Cl)ccc2OC)cs1 +Cc1nn2c(CNS(=O)(=O)c3ccc(C#N)cc3)c(C)nc2s1 +CN(CCC#N)S(=O)(=O)N1CCCC(C(N)=O)C1 +O=C(CSc1nnnn1C1CCCC1)N1CCCC1 +O=C(c1ccsc1)N1CCN(Cc2nnc3n2CCCCC3)CC1 +O=C(NCCNc1cccnc1)c1ccc2[nH]c(C(F)(F)F)nc2c1 +COCc1nc(C)c(C(=O)Nc2cc(-c3cccnc3)n[nH]2)s1 +CCc1nnc(NC(=O)NC(C)C(=O)NCc2ccccc2)s1 +CCS(=O)(=O)N1CCN(c2ncnc3c(C)nn(C)c23)CC1 +COC(=O)c1cc(NC(C)=O)c(Cl)c(NC(C)=O)c1 +CC(=O)Nc1ccc(CN(CCC#N)CC2CC2)cc1 +O=C(c1ccco1)N1CCCN(c2nnc3ccc(Cl)cn23)CC1 +Cc1noc(C)c1C(=O)NCC1CCN(c2ccccc2)C1 +CCOC(=O)CC(C)CNC(=O)c1ccccc1F +COc1ccc(OC)c(NC(=O)C(C)Sc2ccccn2)c1 +NC(=O)C1CCN(C(=O)c2cc(Cl)cc3cccnc23)C1 +CCn1ncc(-c2cccc(OC)c2)c(C(C)=O)c1=O +CCc1noc(C(C)N(C)Cc2nccn2C(F)F)n1 +O=C(COc1ccc(F)cc1)NCCNC(=O)c1ccccc1O +Brc1cc(N2CCCC2)cc2c1NCC2 +Cn1nc(C2CCN(C(=O)c3ccccc3F)CC2)n(C2CC2)c1=O +O=C(CNC(=O)c1ccccc1)NC1CCCN(c2cccnn2)C1 +COc1ccc(-n2ccc(CNC(=O)C3CCC(=O)NC3)n2)cc1 +CC(C)NS(=O)(=O)c1cc(C(=O)N2CCOCC2C)ccc1F +NC(=O)N1CCC(NC(=O)CCc2cccc(C(F)(F)F)c2)C1 +COc1ccc(-c2nc(Cn3cnc(C4CCC4)cc3=O)no2)cc1 +COc1cc(OC)c(C(C)=O)c(OC(C)=O)c1OC +Cc1cccc(C(=O)Nc2nc(C)c(C(=O)N(C)C)s2)c1 +COC(=O)NCCC(=O)N(Cc1ccccn1)c1ccc(Cl)cc1 +COc1ccc(C(=O)N2CCCCCC2)cc1NCc1noc(C)n1 +Cc1cc2c(cc1C)N(Cc1cccnc1)CCN2 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cnc2ccccc2n1 +Cc1ncccc1NC(=O)c1nc2c(n1C)CCN(C(=O)C1CC1)C2 +NC(=O)c1cc2c(nc1N1Cc3cnn(CCO)c3C1)CCC2 +Cc1oncc1C(=O)NCC1CCN(C(=O)NC(C)(C)C)CC1 +Cc1cccc(=O)n1CCC(=O)NCc1ccon1 +N#Cc1cnn(C(=O)c2cccc(OC3CCCC3)c2)c1N +CCN(Cc1cccs1)C(=O)NC1CCCc2c1cnn2CCO +CC(=O)Nc1nc(C(=O)Nc2cc(CC3CCCCC3)n[nH]2)cs1 +Cc1ccc(-c2cnc(NCc3ccncc3)nc2)cc1 +O=S(=O)(NCc1cnn2ccccc12)c1cccnc1 +CC(C)C(=O)NCCNC(=O)NCc1ccncc1 +Cc1ccc(-c2ccc(C(=O)N3CC4OCCN(C)C4C3)s2)o1 +CCc1ccccc1OCCCCN1CCOCC1 +COc1ccccc1CC(=O)N(C)c1ccc(S(C)(=O)=O)cc1 +Cc1ccc(NC(=O)CN(C)Cc2cnc(CC(C)C)s2)nc1 +N#CCCN(C1CC1)S(=O)(=O)c1cc(F)ccc1F +O=C(CCC(=O)N1CCC(c2ccccc2)CC1)N1CCOCC1 +CC(=O)N1CCCC1c1nccnc1-c1ccccc1F +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)N1CCCC1C1CCCC1 +Cc1nc2ccccc2c(=O)n1-c1ccc(O)cc1 +Cc1ccc(NC2CCCN(C(=O)c3ccoc3C)C2)cc1C +O=C(NCCC(O)c1cc2ccccc2o1)Nc1c(F)cccc1F +CC(C)COc1ccccc1CNS(=O)(=O)C(C)C +Cc1cccc(C)c1OCCNC(=O)NCC1CCC1 +COc1ccc(Oc2cc(C)nc(C3CCN(C(C)=O)CC3)n2)cc1 +c1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)nnnc32)cc1 +CCNC(=O)CSc1nncn1-c1ccccc1C +COC(=O)CN1CCN(c2nccnc2C#N)CC1 +CCSc1ccccc1C(=O)N1CC(c2nc(C)no2)C1 +CCOCc1ccccc1CNC(=O)CN1CCOCC1 +c1csc(-c2n[nH]cc2CN2CCCC(c3cnccn3)C2)c1 +COc1cccc(NC(=O)C23CCC(C)(C(O)C2)C3(C)C)c1 +CCCCNC(=O)c1nnn(-c2ccc(Cl)cc2)c1C +CCCNC(=O)C(CC)N(c1cccc(Cl)c1)S(C)(=O)=O +O=C(c1ccc(=O)[nH]c1)N(CCO)CC(F)(F)F +CN(C(=O)CNc1ccc(Cl)cc1C(N)=O)C1(C#N)CCCCC1 +Cc1nc(C)c(C(=O)NCC(O)c2c(Cl)cccc2Cl)s1 +COC(=O)c1sc2[nH]c(CNCc3ccco3)nc(=O)c2c1C +COC(=O)CCCNC(=O)CN1CC(C)OCC1C +COc1cc(OC)cc(OCCC(O)C(C)C)c1 +CCOc1cccc(Cn2c(=O)[nH]c3ccccc3c2=O)c1 +CC(=O)N1CCc2cc(-c3nc4c(N)cccn4c3C)ccc21 +CNC(=O)NCC(=O)NC(c1ccccc1)C(C)(C)C +COc1cccc(C=Cc2nc(N)nc(-c3ccccc3O)n2)c1 +O=C(NCc1ccc(Cl)cc1)N1CCOCC1 +O=C(Nc1ccccc1)N(Cc1ccncc1)CC1CCCO1 +Cn1cnc(CNC(=O)NC(c2ccc(F)cc2)C2CC2)n1 +CC(=O)c1sc(CCOc2cccc(N)c2)nc1C +O=C(c1ccccc1OC(F)F)N1CCN(c2ccc(O)cc2)CC1 +Cc1ccc(C)c(C(=O)NCCc2cn(C)c3ncccc23)c1 +CCc1ccc(NC(=O)CS(=O)(=O)c2ccc(OC)cc2)cc1 +CN(Cc1ccc(F)cc1F)C(=O)c1ccco1 +CC(C)C(NC(N)=O)C(=O)NCc1ccc(F)cc1 +CC(C)CNc1nnc(-c2cc(C(C)C)nn(C)c2=O)s1 +CCc1c(C)sc(NC(=O)c2ccc(Cl)cc2)c1C(N)=O +COc1ccccc1-n1ncnc1CCN(C)S(C)(=O)=O +COc1cccc(OCC(=O)Nc2ccncc2)c1 +COC(=O)CNC(=O)c1ccc(NC(=O)N2CCCC(OC)C2)cc1 +Cc1ccc(F)c(CN2CCNC(=O)C2c2ccccc2)c1 +COc1cccc2c1ccn2CCNC(=O)C(C)C +CC(C)(C)c1n[nH]cc1CNCCc1cc(F)cc2c1OCOC2 +Cc1csc(N(C(=O)CNC(=O)C(C)(C)C)c2ccccc2)n1 +Cc1cc(Br)ccc1OCC(=O)Nc1nccs1 +Cc1cc(C)n(CCN2CCN(C(=O)C3CCCC3)CC2)n1 +CCCOC1CCCN(C(=O)Nc2ncccc2C)C1 +CS(=O)(=O)N(CC(=O)N1CCCC1)c1ccc(F)c(F)c1 +CC(NC(N)=O)C(=O)Nc1ccc(Cl)c(Cl)c1 +CC(C)Oc1ccccc1CNC(=O)c1ccn2nccc2c1 +CC(C)CNC(=O)c1ccc(NC(=O)c2scnc2C2CC2)cc1 +Cc1nc2cc(F)ccc2cc1C(=O)NCCc1ccccn1 +C#CCN1CCN(C(=O)NCc2cccc(Cn3cccn3)c2)CC1 +O=C(CN1CCCC1=O)NC1(c2ccc3c(c2)OCCO3)CCCC1 +CCCN(CCC)c1ncnc2c1cnn2-c1ccccc1 +CC(C)N(C(=O)c1cccc2c1OCCO2)C(C)C +CCCS(=O)(=O)NCc1ccc(SC)cc1 +CN(c1ccc(-c2csc(-c3ccco3)n2)cc1)S(C)(=O)=O +CCC(C)Oc1ccc(NC(=O)C(C)NC(N)=O)cc1 +COc1ccnc(NC(=O)c2c(-c3ccccc3Cl)noc2C)c1 +OC(CCNc1ccccc1)c1ccc2c(c1)CCC2 +CCCN1C=NS(=O)(=O)c2cc(C(=O)NCC(C)C)ccc21 +O=C(Nn1cnc2ccccc2c1=O)c1ccc(-n2ccnn2)cc1 +O=C(c1ccc2c(c1)CCC2)N1CCN(C(=O)C2CCCC2)CC1 +N#Cc1cnn(C(=O)Cc2ccc(-c3ccccc3)cc2)c1N +N#Cc1cccc(NC(=O)Nc2cccc(C#N)c2)c1 +Cc1csc(C2(NC(=O)c3ccc4ccccc4n3)CCCC2)n1 +CCOCCc1nnc(NC(=O)Cc2cccs2)s1 +O=C(NC1CCC(O)CC1)c1cc2cc(Br)ccc2[nH]1 +O=C(c1cc(Cl)ccc1Oc1ccc(F)cc1)N1CCC(O)C1 +Cc1cc(Br)cc(C)c1NC(=O)N(C)Cc1ccccn1 +Cc1cc(C)c(NC(=O)NCc2cn(-c3ccccc3)nn2)c(C)c1 +Cc1ccccc1CS(=O)(=O)N1CCCCCC1 +CN(Cc1nc2ccccc2n1C)C(=O)c1ccccc1-n1cnnn1 +O=C(Nc1ccc(F)cc1)c1ccc(S(=O)(=O)C(F)F)cc1 +COc1ccc(NC(=O)c2cc(OC)ccc2OC)cc1 +COC(=O)c1ccc(F)cc1NC(=O)c1ccnc(OC2CCC2)c1 +Cc1ccc(NC(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)cc1 +CCCC(C)(CO)NC(=O)NCC1(c2ccc(F)cc2)CC1 +O=C(CCOc1ccc(Cl)c(Cl)c1)NCc1ccccn1 +O=S(=O)(Cc1ccccc1F)N1CCN(c2ccccc2)CC1 +COC1C2CCC1CN(c1ncnc3c1Cc1ccccc1OC3)C2 +CC(C)CCNC(=O)NC(C)C(=O)NCc1ccccc1 +COc1ccc(OCC(=O)Nc2nc3ccc(OC)cc3s2)cc1 +Cc1csc(N2CCN(Cc3nnc(C4CC4)o3)CC2C)n1 +CCOC(=O)c1sc(NC(=O)CN2C(C)COCC2C)cc1C +CSc1cc(C)c(OC(=O)Nc2c(C)cccc2C)c(CO)c1 +Cc1ccc(S(=O)(=O)N2CCN(C)Cc3ccccc32)s1 +O=C(CCc1nc2ccccc2s1)NCCc1ccccc1 +COC(=O)C1C(=O)C2C(=NC(C(=O)OCC3CCCO3)=C2C)CC1C +Cc1nn(C)c2sc(C(=O)NC3CCCCNC3=O)cc12 +CCCN(C)S(=O)(=O)N1CCC(OCc2ccc(F)cc2)CC1 +C#CCNC(=O)CNC(=O)c1ccc(F)c(F)c1 +CCOc1ccc(-c2cn(Cc3ccncc3)nn2)cc1Cl +Cc1csc(C2CN(Cc3cnc4ncccn34)CCO2)n1 +Cc1noc(C)c1CN1CCN(Cc2cc(F)c(F)cc2F)CC1 +O=S(=O)(NC1CCc2c(Cl)cccc21)N1CCCCC1 +Cn1ccc(C(=O)N(Cc2ccco2)Cc2ccco2)cc1=O +Cc1cc(C)n(-c2oc(-c3cccnc3)nc2C#N)n1 +N#Cc1cccc(OS(=O)(=O)c2cccc(C#N)c2)c1 +Cn1cc(NCc2c[nH]nc2-c2cccs2)cn1 +CCCCNC(=O)Cc1noc(-c2nc3nccc(C)n3n2)n1 +OCc1c(-c2cccs2)nc2ccc(Cl)cn12 +COc1ccc(Cl)cc1-n1cccc(C#N)c1=O +COc1cccc(C(=O)Nc2ccccc2-n2ccnn2)c1F +CCC(C)CS(=O)(=O)c1nc2ccccc2[nH]1 +CCCN(C)C(=O)c1ccc(OC)c(C#CCO)c1 +CC(C)CCn1c(C2CC(=O)N(C3CC3)C2)nc2ccccc21 +Cc1ccc(C(=O)OCC(=O)NC(C)c2cccs2)cc1O +Cc1ccn(C(C)(C)C(=O)Nc2cccc(N)c2)c(=O)c1 +O=C(NCC1(c2ccc(F)cc2)CC1)c1ccc2[nH]cnc2c1 +CC(NC(=O)c1ccc(=O)n(C)c1)c1ccccc1 +O=C(OCc1cccc2cccnc12)C1CCCCN1c1ncccn1 +CCOC(=O)c1csc(NC(=O)C2CC=CC2)n1 +CCOC(=O)C1CCCN1C(=O)CN(C)C(C)=O +CCCn1nc(-c2nc(COC)no2)ccc1=O +CCOC(=O)COC(=O)c1cnc2ccc(C)cn12 +COC(=O)C(C)(C)NC(=O)Cc1c[nH]c2ccc(OC)cc12 +CCc1ccccc1CC1Oc2ccc(O)cc2N(CCO)C1=O +CC(Nc1cccc(Cl)c1C#N)c1cccnc1 +COC(=O)c1ccc(NS(=O)(=O)c2ccc(NC(C)=O)cc2)cc1 +Cc1cccc(NC(=O)COc2ccc(CC#N)cc2)c1 +COc1ccc(-c2nc3cc4c(cc3n2CCC#N)OCO4)cc1 +C#CCN(Cc1ccc(F)cc1)C(=O)CNC(=O)OC +CC(=O)Nc1ccccc1Oc1ccc(Br)cc1N +COCCN1CCN(S(=O)(=O)c2cc(F)ccc2F)CC1=O +CCCNC(=O)CS(=O)(=O)c1nnc(NC(C)(C)C)s1 +O=C(Cc1cccc(O)c1)N1CCC(C(=O)N2CCCCCC2)CC1 +CC(=O)N1CCc2cc(CNC(=O)Nc3cccc(C)c3)ccc21 +COCCN(C)C(=O)COc1ccc(F)c(Cl)c1 +COc1ccc(N2CCCC(C(=O)N3CCCC3)C2)nn1 +Cn1c(NC2CCOc3ccccc32)c(C#N)c(=O)n(C)c1=O +N#Cc1ccsc1NC(=O)COc1ncnc2ccccc12 +COc1ccc(-c2c(C(C)C)c[nH]c(=O)c2C#N)cc1OC +O=C(CCc1ccccc1)N1CCN(CCn2cccn2)CC1 +COc1ccccc1CC(=O)Nc1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCNC(=O)c1ccc(C)c(NC(=O)NC(C)(C)CO)c1 +Cc1cccc(C(=O)N2CCCCCC2c2ccncc2)c1O +O=C(NCCC(=O)N1CCCCC1)c1cncc2cnccc12 +Cc1nc(SCC(=O)NC(C)C2CC2)c2c(C)c(C)sc2n1 +Cc1csc(NC(=O)NCc2ccc(Cl)cc2)n1 +O=C(Cn1ccnc1-c1cnccn1)Nc1cccc(C(F)(F)F)c1 +CN(C)c1ccc(C(=O)Nc2ccc(C#N)c(Cl)c2)cc1 +Cn1nc(CNC(=O)c2ccncc2)c2c1CCCC2 +CC(C)Cn1nc(C(=O)NC(C)C2CC2)c2ccccc2c1=O +COc1ccccc1OC1CCN(C(=O)c2ccnc(N)c2)CC1 +CC1CC1C(=O)Nc1ccc(Sc2nncs2)cc1 +COc1ccc2ccccc2c1CNc1cc(C)no1 +CCCn1c(N)c(Nc2cnn(C)c2)c(=O)[nH]c1=O +CN(CCc1ccccn1)C(=O)c1cnn(-c2ccccc2)n1 +O=C(COc1ccc(Cl)cc1)Nc1cccc(C(=O)NC2CC2)c1 +CCN(CC)C(=O)c1cc(C)nc2c1c(C)nn2CC +COCCCNC(=O)Cn1c(=O)c2cccn2c2ccc(F)cc21 +Cc1cc(N2CCCC2)nc2sc3c(N(C)CCO)ncnc3c12 +O=C(NCc1ccccn1)c1cn2c(n1)CCCC2 +O=C(Cc1noc(COc2ccccc2)n1)NC1CCCC1 +CCN(Cc1cnc(C)s1)Cc1ccccc1C +Nc1ncccc1COc1cccc(Cl)c1Cl +COCc1ncc(C(=O)NCc2ccccc2F)c(N)n1 +CC(=O)NCC1CCCN(C(=O)c2c(C)nn3c(C)cc(C)nc23)C1 +CCOCC1(CNC(=O)Nc2ccc(SC)cc2)CCC1 +O=C(c1cn(-c2ccccc2)nc1-c1cccnc1)N1CCCCC1 +CCC1CN(C(=O)NCc2ccccc2F)CCO1 +O=c1[nH]c2ccccc2n1-c1cncc(Br)c1 +CCCCC(=O)Nc1cccc(-c2cn3cccnc3n2)c1 +COc1ccc(C)cc1NC(=O)CSc1nc(O)nnc1C +Cc1ccc2ncc(C(=O)Nc3ccc(Cl)c(Cl)c3)c(=O)n2c1 +O=C(Cn1nnc2ccccc21)Nc1cc(N2CCCCC2)ncn1 +COc1cc(NC(=O)NC2CCCC2)ccc1N1CCOC1=O +CNC(=O)NCC(O)COc1ccc(C(F)(F)F)cc1 +O=S(=O)(N1CCCCCC1)N1CCN(CC(F)(F)F)CC1 +CN(C)c1ccc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)cn1 +O=C(c1cc(Cl)ccc1Cl)N1CCOCC1C1CC1 +COc1cc(NC(=O)Oc2ccccc2)ccc1C#N +O=C(Cn1c(=O)oc2ccccc21)NCC1COc2ccccc2C1 +Cc1nnc(NC(=O)Cc2nc3cc(N)ccc3o2)s1 +CC(c1cccnc1)N(C)C(=O)NCC(C)N1CCOCC1C +CC1CCN(C(=O)c2cc3cn(C4CC4)cc3s2)CC1 +NC(c1cc(Cl)cc(F)c1Cl)C(F)(F)F +Cc1ccc(C(O)CNC(=O)c2ccc(Cl)cc2)c(C)c1 +O=C(NCCCc1ccc(Cl)cc1)c1cscn1 +CC(C)CNC(=O)NCc1ccc(Oc2cccnc2)c(F)c1 +COc1ccc(S(=O)(=O)N(C)CCC(F)(F)F)c(C)c1F +Cc1ncsc1C(=O)N1CCC(N2CCOC(C)C2)CC1 +COC(=O)NCC(=O)N1CCCC1c1ccc(Cl)cc1 +Cc1ccc(-n2nnnc2SCCC#N)c(C)c1 +CCCCn1nc(C(=O)N(C)CC(C)C#N)ccc1=O +CC(=O)Nc1nc2ccccc2n1CCOc1ccc(F)cc1 +CC(C)(CNC(=O)c1cccc(Nc2cnccn2)c1)c1ccncc1 +NC(=O)c1cccc(C(=O)OCCc2cccs2)c1 +CC(C)n1ncc2cc(C(=O)Nc3ccccc3)cnc21 +COc1ccc(S(=O)(=O)N(C)C(C)c2ccccc2)cc1OC +Cc1ccc(N2CCCN(C(=O)c3ccsc3)CC2)nn1 +Cc1cc(CN2CCN(C(=O)C(c3ccccc3)N(C)C)CC2)on1 +CN(C)c1cc(C(=O)Nc2ccc(-n3cncn3)c(F)c2)ccn1 +Cc1cccc(NC(=O)C2CCN(CC(F)(F)F)CC2)c1C(N)=O +Cc1ccc(OCCn2c(C)ccc(C#N)c2=O)cc1 +COc1cc(C)c(S(=O)(=O)NCc2ccc3c(c2)OCO3)cc1C +O=C(c1cncc(Br)c1)N1CCCC1Cc1ccccc1 +CC(C)(C)NC(=O)c1cccc(NC(=O)C2(C#N)CCCC2)c1 +C#CCNC(=O)C1CCN(c2ccc(Cl)cn2)CC1 +Cc1ccc(CNC(=O)Nc2ccc(F)c(C#N)c2)s1 +COC(=O)C1=C(C)N(C)C(=O)N(C)C1c1ccc(C)s1 +COc1ccnc(NC(=O)C2(c3ccc(F)cc3)CC2)c1 +CSc1sc(NC(=O)CCNC(=O)C(C)(C)C)nc1C +COC(=O)C1(N(C)C(=O)c2ccc(C(C)=O)cc2)CCCCC1 +CCOc1ccc(C2=CCN(C(=O)NC3CCOC3C)CC2)cc1 +O=C(NCC1CCC1)c1ccc(-c2nc(C3CC3)n[nH]2)cc1 +Cn1c(SCC(O)COc2ccc(C#N)cc2)nnc1C1CC1 +CC(C)OCC(O)CN1CCN(CC(=O)N2CCCCC2)CC1 +CC(C)(CCCNC(=O)Cc1cccnc1)C1OCCO1 +CC(CC(=O)N1CCC2(CC1)OCC(C)O2)NC(=O)c1ccccc1 +OCC1CN(Cc2ccccc2)CC1CN1CCOCC1 +CCc1noc(CC)c1CC(=O)NC1CCCCC1 +CC(C)c1cccc(CN(c2cccc(C#N)c2)S(C)(=O)=O)n1 +N#CCc1ccc(NC(=O)c2ccc(Cn3ccnc3)cc2)cc1 +Cc1nn2c(C(F)F)cc(-c3ccco3)nc2c1Br +Cc1cc[nH]c(=NS(=O)(=O)c2cccc(F)c2F)c1 +CC(C)n1nccc1C(=O)NC1CCN(C(=O)NC(C)(C)C)CC1 +CN(CCNC(=O)C1CC(=O)N(C2CC2)C1)c1ccccc1 +COCc1ccccc1NCC(=O)Nc1ccc(OC)cc1 +CCOc1cccc(C(=O)NCc2ccc(OC)c(OC)c2)c1 +NC(=O)c1ccc(OCC(=O)Nc2c(F)cccc2F)cc1 +COc1ccc(C(C)NC(=O)c2ccc(-c3ccsc3)nc2)cc1 +CCOC(=O)CN(C(=O)c1ccccn1)C(C)C +CC1CC(NC(=O)Cc2ccc[nH]2)C(=O)N1c1ccccc1 +CC(C)(O)CN1CCN(C(=O)c2cncn2-c2ccccc2)CC1 +CCN1CCOC(C(=O)Nc2cc(F)ccc2N2CCCCC2)C1 +COC(=O)c1ccc(NC(=O)Cn2ccc(=O)c3ccccc32)s1 +CC(C)N(Cc1ccccn1)C(=O)CCc1cc(F)ccc1F +C=CCOC(=O)N1CCC(=O)CC1c1ccccc1 +CC1CN(C(=O)Cc2cccs2)c2ccccc21 +C=CCNC(=O)CSc1nnc(-c2ccccc2OC)n1N +CC(C(=O)NCc1ccncc1)n1nc(-c2ccccc2)ccc1=O +O=C(c1ccoc1)N1CCN(C(=O)c2cccc(F)c2)CC1 +CN(CCc1ccc(F)cc1)C(=O)c1cc2cc(F)ccc2[nH]1 +CN(C)C(CNCc1cccc(F)c1)c1ccc(F)cc1 +COC(CNC(=O)CCc1ccccc1F)c1ccsc1 +O=C(Nc1cccc(F)c1)C1CN(C(=O)c2c[nH]c3ccccc23)C1 +Cc1ncsc1C(=O)Nc1ccc(CNC(N)=O)cc1 +C=CCN(C(=O)CCNC(=O)c1ccccc1F)C1CCCC1 +CC1CCN(c2ncc3c(n2)CN(C2CCCCC2)C3=O)CC1 +CC(C)(C)OC(=O)NCCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +CNC(=O)c1cccc(CNC(=O)c2ccc(-c3ccco3)nc2C)c1 +CCN(CC)C(=O)c1ccccc1NC(=O)N(C)Cc1ccccn1 +COc1ccc(NC(=O)Cn2ncnc2-c2ccccc2Cl)cc1 +CC(=O)Nc1cc(NC(=O)c2cnc3ccc(C)cn23)ccc1F +Cc1nnc(-c2cccc(C(F)(F)F)c2)[nH]c1=O +O=C(NCCC(=O)N1CCCC1)NCCc1cccs1 +COCc1ccccc1NC(=O)CCSc1ccccn1 +COc1ccc(Cc2nnc(SC(C)C(=O)N3CCCC3)o2)cc1 +NC(=O)c1ccc(-c2nnn(Cc3cccc(C(F)(F)F)c3)n2)cc1 +CCc1nc(C2CCCN(S(=O)(=O)c3ccc(F)cc3)C2)no1 +CC(C)(C)OC(=O)N1CCn2c(nnc2C(F)(F)F)C1 +CNC(=O)c1ccc(Cl)cc1NCC(=O)NC1(C#N)CCCCC1 +CCn1cnnc1CNC(=O)c1cnn(Cc2ccccc2Cl)c1 +CCOC(=O)c1sc2ncnc(N3CCCC(C)C3)c2c1C +COC1CCCC(OC(=O)c2cccc3c2ccn3C)C1 +CCOC(=O)COc1cc(C(=O)OC)ccc1N +O=C(Cc1c(F)cccc1F)Nc1cnn(-c2ncccn2)c1 +Cc1nc2cc(C(=O)N3CCN(c4ccccc4)CC3)ccc2[nH]1 +O=C(NCc1cccc(OCc2ccccc2)c1)C1CCCO1 +CC(=O)Nc1ccc(S(=O)(=O)NC2(C)Cc3ccccc3C2)cc1 +Cn1c(=O)c(C(=O)NCC2COc3ccccc3C2)nc2ccccc21 +CCC(C)n1ncc(C(=O)Nc2ccc3[nH]c(C)cc3c2)c1C1CC1 +CN(C)C(=O)c1ccc(C(=O)Nc2ccc(C(N)=O)c(Cl)c2)cc1 +Cc1cccc(-c2noc(C(=O)Nc3ncccc3C)c2N)c1 +CC(=O)N1CCN(C(=O)CSc2ccc(F)cc2)CC1 +COCCCC1(CO)CCCN(c2cccc(C(F)(F)F)n2)C1 +CC1CC(=O)N(C)c2ccccc2N1S(=O)(=O)c1cccs1 +Cc1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)c2)cc1 +CC1Oc2cc(N)ccc2N(CCc2ccccc2)C1=O +Cc1cc(NC(=O)N(CCO)C2CC2)ccc1Oc1cccnc1 +Cc1csc(S(=O)(=O)CC(=O)Nc2ccccc2)n1 +Cc1[nH]ncc1CCCNC(=O)Cc1ccc(F)cc1 +Cc1nc2[nH]nc(O)c2c2c1c(=O)oc1ccc(Cl)cc12 +CCC(C)Oc1ccc(NC(=O)C2CC(=O)N(C(C)C)C2)cc1 +c1ccc2c(c1)CC(NCc1cnc(N3CCOCC3)s1)CO2 +Cc1cccc(CCNC(=O)c2ccccc2N2CCOCC2)c1 +COCCNC(=O)N1CCN(c2nc3c(C)ccc(C)c3s2)CC1 +CCC(NCc1cc(Cl)cc2cccnc12)C(=O)N1CCOCC1 +Cc1cccc(C)c1NC(=O)CNC(=O)c1ccc(NC(N)=O)cc1 +COCC(NC(=O)c1oc2c(OC)cccc2c1C)C(N)=O +CCOc1ccc(C2CCCN2C(=O)NCc2csc(C)n2)cc1 +COc1cc(C(=O)N(Cc2cccc(C)c2)C2CC2)on1 +COCCNC(=O)NCC(C)c1nc(-c2ccccc2)no1 +C=CCn1c(C)nnc1SCC(=O)N(C(C)C)C(C)C +CC(C)C(=O)Nc1cccc(C(=O)n2nnc3ccccc32)c1 +COc1ccc(CNc2cc(OC)nc(CC(C)C)n2)cc1 +CSc1nnc(NC(=O)Cc2ccc(Cl)cc2)s1 +COc1ccc(C(=O)Nc2c(C)cc(C)cc2C)c(OC)c1OC +COc1ncccc1CNC(=O)NCC1CN2CCCCC2CO1 +CCc1ccc(C(=O)NCc2ccnc(OC)c2)o1 +CCC1CCCCC1NC(=O)CNC(=O)CNC(C)=O +Cc1cccc(C(C(=O)NCCC(=O)Nc2nccs2)N(C)C)c1 +COC(=O)c1cc(-c2ccc(OC(C)C)c(OC)c2)n[nH]1 +CN(C)c1c(Cl)cccc1NC(=O)COCC1CC1 +CCOC(=O)c1c(NCc2cccs2)c2cccc(C)c2[nH]c1=O +CC(=O)c1cccc(NS(=O)(=O)c2cc(C)sc2C)c1 +O=C(NCc1ccccc1Cl)C1CCCN(c2cnccn2)C1 +O=S(=O)(c1ccc(NCCc2ccccc2F)nc1)N1CCCC1 +Cn1nc(CNC(=O)Cc2cccc3ccccc23)cc1-c1ccco1 +COc1ccc(Nc2cc(C#N)ccn2)cc1Cl +CCC1(O)CCN(C(=O)c2ccccc2N(C)C)CC1O +O=C(COc1nnc(-c2ccccc2)o1)NCc1ccco1 +COc1ccc(C(=O)Nc2ccccc2F)cc1N +O=S(=O)(NC1CCC(O)CC1)c1ccc(F)cc1F +CCC(CCO)NC(=O)Nc1ccccc1C(=O)N1CCCCC1 +COc1cccc(C(O)COc2cccc(-n3cccn3)c2)c1 +CCNC(=O)N1CCCN(c2ncccc2C#N)CC1 +Cc1csc(NC(=O)C2(c3cc(-c4ccco4)on3)CC2)n1 +NC(=O)CN1C(=O)CCS(=O)(=O)c2ccccc21 +CCN(CCO)C(=O)COc1ccc2c(c1)CCC2 +Cc1ccc(C(=O)N2CCOCC2C2CC2)cc1Oc1ccncc1 +CC(C)(Sc1ccccc1Cl)C(=O)N1CCNCC1 +Cc1sc(=O)n(CCC(=O)NCC(C)(C)c2ccncc2)c1C +Cc1cc(C(=O)N2CC(C(=O)Nc3ccc(F)cc3)C2)no1 +COc1cc(NC(=O)CN2CCOCC2C2CC2)cc(OC)c1 +COc1cccc(C2NCCc3c(O)ccc(F)c32)c1 +COc1ccc(Br)cc1CN(C)CC(C)C#N +COCCN(Cc1ccc2c(c1)OCO2)Cc1nc(C)cs1 +CC(=O)NC(C)C(=O)NCCOc1cccc(C)c1 +CCOC(=O)c1ccc(NC(=O)c2ccc(NC(=O)CC)cc2)cc1 +NC(=O)NCc1ccc(C(=O)NCc2ccccc2Cl)cc1 +CCCN(C)C(=O)Nc1nc(-c2ccc[nH]2)cs1 +O=C(NCc1ccco1)C1CC12C(=O)Nc1ccccc12 +O=C(NCCCc1ccccc1)c1cc2ccccc2oc1=O +CC(C(=O)NCc1ccc(-n2cncn2)cc1)c1ccsc1 +Cn1c(N)nnc1SCc1cn2ccccc2n1 +Cn1nccc1C(=O)Nc1cnn(-c2ccccc2F)c1 +CN(CCc1ccc(F)cc1)C(=O)c1ccc(S(N)(=O)=O)o1 +CC(C)C(=O)NCc1cccnc1N1CCNC(=O)C1 +CCn1c(C)cc(C(=O)Nc2cccc(SC)c2)c1C +O=C1CN(C(=O)COc2ccc(Oc3ccccc3)cc2)CCN1 +Cc1cc(C(=O)N2CCN(C)CC2c2ccccc2)n(C)n1 +CCn1nc(C(=O)NCCn2nc(C)cc2C)ccc1=O +COC(=O)c1ccccc1NC(=O)NCc1ccccc1OC +Cn1nc(-c2cccs2)cc1C(=O)NCC(N)=O +O=C(Cc1cccc(F)c1)Nc1cc(F)cc(F)c1 +COc1ccc(F)c(NC(=O)c2ccc(CNS(C)(=O)=O)o2)c1 +CCC(C(N)=O)N(c1cc(C)cc(C)c1)S(C)(=O)=O +N#Cc1ccc(OC(=O)C2CC2c2ccco2)cc1 +COc1cc(Cl)ccc1CNCc1sc(C)nc1C +C#CCN(CC#C)Cc1cc(Br)c(OC)s1 +CCOC(=O)c1c(C#N)cnn1-c1cccc(Cl)c1 +COCCCCN1CCc2ccc(Cl)cc2C1 +CCOC(C)C(=O)Nc1ccc(Oc2ccccc2OC)c(F)c1 +CN(C)c1cccc(OCCNCC(F)(F)F)c1 +CC(Sc1ncc2ccccn12)C(=O)NC(C)(C)C +Cc1nn(C)c(C)c1C(=O)NC1CCN(c2c(F)cccc2F)C1 +CCc1nc2n(n1)CCCC2NC(=O)NCC(C)c1cccc(C)c1 +CCOC(=O)c1ccc(NC(=O)CCn2ncc3ccccc32)cc1 +COc1ccc(C(=O)NCC(C)(C)c2ccncc2)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)NCC1CCCC1O +Cc1nc(N)nc(-c2ccccc2OC(C)C)c1C(N)=O +CCc1ccc(OC)c(CN2C(=O)CNc3ccccc32)c1 +O=C(Cn1nc(-c2cccs2)ccc1=O)Nc1cccc(F)c1 +CC(C)N(C(=O)c1cc(C(=O)c2ccc(F)cc2)c[nH]1)C(C)C +Cc1csc(-c2ccc(C(=O)N3C(C)COCC3C)cc2)n1 +COc1ccc(Br)cc1-c1noc2c1CCN2 +Cc1occc1CN(C)S(=O)(=O)c1ccccc1C(F)(F)F +O=C(COCC(F)(F)F)NCc1ccccc1-n1ccnc1 +O=C(Nc1cccnc1)c1cc2occc2n1Cc1ccccc1F +Cc1cc(C)n(CCOC(=O)c2ccc3c(c2)NC(=O)CS3)n1 +N#Cc1ccc(OCC(=O)NCc2ccc(F)cc2)cc1 +Cc1cc(S(=O)(=O)N2CCNC(=O)CC2)ccc1Br +CNC(=O)C1CN(C)CCN1c1nc(C)cc(C)n1 +CCc1nc(C(CC(C)C)NC(=O)OC(C)(C)C)no1 +COc1ccc(C(=O)Nc2cc(Cl)c(N)cc2Cl)cc1OC +CCN(CC(=O)NC(C)(C)C)C(=O)CCc1cc(Cl)cs1 +COc1ccc(C2(CNCc3sc(C)nc3C)CCOCC2)cc1 +CCc1ccc(C2COCCN2S(=O)(=O)c2ccc(C#N)cc2)o1 +CCc1cccc(C)c1NC(=O)NC1COc2ccc(OC)cc2C1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)Nc1ccc2c(c1)CCC2 +CC(=O)C(C)CSc1nnnn1-c1ccc(C)cc1 +CCOc1cccc2c1C(c1ccc(C#N)c(F)c1)NCC2 +Cc1cc(NC(=O)c2ccccc2S(C)(=O)=O)c2ncccc2c1 +Cc1cc2c(cc1O)C(c1c(C)ncnc1C)NCC2 +O=C(Nc1cccc2ccccc12)c1c[nH]c2c(Cl)cccc2c1=O +O=C(Cc1cccnc1)Nc1ccc(Cl)cc1O +Cc1cccc(-n2nc(C)nc2CNC(=O)c2ccccc2)c1 +O=S(=O)(NCc1ccc(F)cc1)c1cc(F)cc(F)c1 +CCOC(=O)Cc1csc(NC(=O)c2cc3n(n2)CCCO3)n1 +COC(=O)CCC(=O)Nc1cccc(-c2cnco2)c1 +CC(=O)c1ccc(NC(=O)CNC(=O)c2cccc(C)c2)cc1C +OCCCOc1ccc(-c2ccc3c(c2)OCCO3)cc1 +CN(C)c1cccc(C(=O)N2CC(Oc3ccccc3Cl)C2)c1 +CCOC(=O)c1sc(Nc2nc(C)c(CC)c(=O)[nH]2)nc1C +Cc1ccc2[nH]c(C)c(CN3CCOCC3)c(=O)c2c1 +Cc1ccc(-c2nnc(C)c(N3CC(C)OC(C)C3)n2)cc1 +Cc1cnc(CN(C)Cc2nc3ccccc3n2C)cn1 +O=C(NCc1ccc2cc[nH]c2c1)C1CC(=O)N(C2CCCC2)C1 +COc1ccc(OC)c(Cc2ccc(OC)c(N)c2)c1 +COCC1(O)CCN(S(=O)(=O)c2ccccc2OC)CC1(C)C +Cc1cccc(-n2cc(C(=O)N3CCCC3c3ccc[nH]3)nn2)c1 +COC(=O)c1ccc(NCc2ccc(C)s2)nc1 +COCCCNc1ncc(Br)c2c(F)ccc(N)c12 +CC1CNC(c2ccc(S(C)(=O)=O)cc2)CO1 +COCCNc1ncnc(Nc2ccc(C(C)C)cc2)c1N +CCOCCCNC(=O)Nc1cc(-c2ncco2)ccc1C +CCn1c(-c2cc(NC(=O)C3CC3)[nH]n2)cc2cc(OC)ccc21 +CC(=O)NCC1NCCc2c(F)ccc(Cl)c21 +CC(O)(CNC(=O)C#Cc1ccc2c(c1)OCO2)c1ccc(F)cc1 +COc1ccc(-c2cc(C)nc(N)n2)cc1C(C)C +COC1CCCN(C(=O)c2ccc(-c3ccsc3)nc2C)C1 +O=C(C1CCCO1)N1CCCC(N2CCNC2=O)C1 +Nc1nc(SCCOc2ccc3ccccc3c2)n[nH]1 +NC(=O)c1ccsc1NC(=O)CSc1nncs1 +O=C(Nc1ccc2c(c1)nc1n2CCCCC1)c1ccc2[nH]nnc2c1 +O=C(Cc1ccc2c(c1)CCCC2)NCCc1ccccn1 +O=C(Nc1cccnc1)N(CC1CCOC1)C1CC1 +Cc1nc(CN(C)C(=O)Nc2cn[nH]c2)cs1 +COc1ccc(CNC(=O)Nc2cccc(F)c2)cc1OC +O=C(NCCO)Nc1ccccc1C(=O)N1CCCC1 +O=C(NCCCN1CCOCC1)NCCc1cccc2ccccc12 +CCn1nccc1C(=O)NCc1ccccc1Cl +Cc1ncc(CNC(Cc2ccsc2)c2nc(C)c(C)s2)cn1 +CC=CCCNC(=O)CCCc1cc(F)ccc1F +CNc1ncccc1S(=O)(=O)NCCn1cccn1 +CCN(CC)C(=O)Cc1cc(OC)ccc1OC +CNS(=O)(=O)c1ccc(Cl)c(C(=O)N(C)CC(N)=O)c1 +COc1cc(C)c(C(=O)Nc2ccncc2)cc1OC +CCn1cc(C(=O)Nc2ccc(C)cc2)c(=O)c2ccc(C)nc21 +Cc1ccc(Cl)cc1Nc1nc[nH]c(=O)c1N +CNc1nc(CNc2ccc(C(=O)Nc3ccccc3)nn2)cs1 +Cn1ccc(NC(C(N)=O)c2cccc(Br)c2)n1 +CCc1noc(C2CC(=O)N(c3ccccc3)C2)n1 +COc1ccc(OC)c(NS(=O)(=O)c2ccc(F)c(C)c2)c1 +O=C1CCCc2nc3c(-c4ccc(Cl)cc4)cnn3cc21 +Cn1cc(CN2CCC3OC(C(=O)NC4CC4)CCC32)cn1 +Cc1ccc(CNC(=O)Cc2ccc[nH]2)c(N(C)C)c1 +C=CCN(Cc1ccc(NC(C)=O)cc1)CC(F)(F)F +N#Cc1cccnc1NCC(O)COc1cccc2ccccc12 +CC(C)Oc1ccc(C(=O)N(C)c2ccc(S(C)(=O)=O)cc2)cn1 +Cc1[nH]nc(C(=O)Nc2ccc(Cl)cc2F)c1N +CC(=O)Nc1ccc(S(=O)(=O)CC#CCO)cc1 +COc1cccc(COC(C)C(=O)N2CCc3sccc3C2)c1 +O=C(Cc1c[nH]c2ncccc12)NCc1cccc(C(F)(F)F)c1 +N#CCCn1ncc2c(NCc3ccc4c(c3)OCO4)ncnc21 +CCCN(CC)S(=O)(=O)c1cc(N)ccc1F +O=C(Cc1csc(-c2ccsc2)n1)NCC(O)c1ccccc1 +CN(Cc1cnccn1)CC1CCCCN1C(=O)OC(C)(C)C +CCC(OC(=O)c1ccco1)C(=O)NCc1ccc(C)cc1 +CC(C)(NCC(=O)NCC(=O)N1CCCC1)c1ccc2c(c1)OCO2 +CCOc1ccc(Br)cc1C(=O)NC +O=C(C1CC1c1ccco1)N1CCCC1Cn1cccn1 +Cn1c(COc2ccc(-n3cncn3)cc2)nnc1C1CC1 +CCCS(=O)(=O)N1CCCC1C(=O)Nc1cc[nH]n1 +Cc1ccccc1OCC(=O)OCC(=O)C1=NC=CC1 +CCN(C(=O)c1ccc(C#N)cn1)c1ccccc1S(=O)(=O)CC +Cc1ccc(F)cc1NC(=O)CCS(=O)(=O)c1ccccc1F +COC(CCc1ccc2[nH]c(=O)[nH]c2c1)(OC)OC +Cn1cc(CCC(=O)NCC(=O)N2CCCC2)cn1 +CCOc1ccc(C(=O)NC(C(=O)Nc2ccncc2)C(C)C)cc1 +COCCCN1CC23C=CC(O2)C(C(=O)OC)C3C1=O +Cc1csc(NC(=O)Cn2c(=O)c(C#N)cn(C3CC3)c2=O)n1 +CCNC(=O)c1cccc(CNC(=O)C2CCC2)c1 +CCc1ccc(CCNC(=O)NCCc2ccc(C)nc2)cc1 +CCSc1nnc(-c2c[nH]c3ccccc23)n1CC +CC1(C)Cc2ccc(C(=O)N3CCCC3)c(O)c2O1 +Cc1ccc(C(C)N(C)C(=O)CCCNC(=O)c2cccs2)cc1 +Cc1cc(C(=O)Nc2cccc(N3CCCC3)c2)[nH]n1 +CC(C)(C)NS(=O)(=O)Cc1cccc(NC(=O)c2ccncc2)c1 +COC(=O)C1CCN(C(=O)c2cccc(-c3ccccn3)c2C)CC1 +CC(C)COc1ccc(-n2nnc(CO)c2C(C)C)cc1 +CCS(=O)(=O)NCCNS(=O)(=O)c1cccc(Cl)c1 +Cc1ccc(OCCNC(=O)NC(C)C(C)CO)cc1 +N#Cc1ccc(N2CCN(CC3=CCCOC3)CC2)c(F)c1 +O=C(c1ccc(OC2CCC2)cc1Cl)N1CCc2[nH]ncc2C1 +COc1ccc(CNC(=O)c2ccc3c(=O)n4c(nc3c2)CCC4)cc1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)N(C)C(C)CC#N)c1 +Cc1cccc(CNS(=O)(=O)c2cccc(F)c2)n1 +O=C(Nc1nc2c(s1)CN(C(=O)c1ccsc1)CC2)C1CCC1 +CC(C)C(NS(=O)(=O)c1ccc(F)c(C#N)c1)C(N)=O +COc1cccc(C(C#N)NC(=O)c2cccc(F)c2F)c1OC +CC(=O)N1CCc2nc(C(=O)Nc3ccccc3)sc2CC1 +CCc1ccc(S(=O)(=O)NC2CCN(c3ccccc3)C2=O)cc1 +CCCC1CN(C(=O)c2cc(-c3ccccn3)ccc2Cl)CCO1 +Cc1cc(NC(=O)N2CCN(CCNC(=O)C3CCCC3)CC2)no1 +O=C(Nc1nc2c(s1)CCC2)c1cc2cc(F)ccc2[nH]1 +CCn1nnnc1-c1cccc(NC(=O)NC(C)C(C)C)c1 +Cc1ncncc1C(=O)N1CC(CO)C(CN2CCOCC2)C1 +O=C(NCCc1ccccc1F)C1CC1c1ccco1 +Cc1cc(C(=O)OCC(=O)c2ccc3c(c2)OCCO3)c(C)o1 +Nc1cccc2c(NC3CC3)ncc(Br)c12 +COc1ccc(N)cc1NS(=O)(=O)c1c(C)noc1C +NS(=O)(=O)c1ccc(Cl)c(C(=O)NCCC2=CCCCC2)c1 +CNC(=O)c1cccc(NCC(=O)NCCC2=CCCCC2)c1C +CC(=O)Nc1ccc(NC(=O)c2cc(Cl)ccn2)cc1Cl +Cc1ccnc(NC(=O)CN2CCN(c3ccccc3F)C2=O)c1 +Cn1c(COC(=O)C2CC3CCC2C3)nnc1-c1ccccc1 +Cc1noc(C)c1CN1CCOC2CN(Cc3cnn(C)c3)CC21 +CCN(CC)S(=O)(=O)c1cc(NC(=O)C2CCC2)ccc1Cl +COc1ccccc1CC(=O)N1CCc2[nH]ncc2C1 +Cn1c(=O)c2nnc(N3CCOCC3)nc2n(C)c1=O +CCc1nnc(CN2CCN(c3ccc4nncn4n3)C(C)C2)o1 +Cn1cc(CC(N)=O)c2cc(Br)ccc21 +CN(Cc1ccc(OC(F)F)cc1)C(=O)COc1ccccc1 +O=C1NCC2(CCCN(C(=O)c3cn4cc(Cl)cnc4n3)CC2)O1 +CC(C)(C)OC(=O)CSc1ncc2ccccn12 +CC1CN(C(=O)NC(c2ccc3c(c2)OCCO3)C(C)C)CC(C)O1 +CC1COCCN1Cc1ccc(-c2ccccc2)o1 +CC1Cc2ccccc2N1S(=O)(=O)CC1CCCCO1 +CC(NC(=O)Nc1cccc(F)c1F)C(=O)OC1CCCC1 +CC(=O)Nc1cccc(NC(=O)CNC(=O)NCc2ccco2)c1C +CSc1nc(=O)n(CCCN2CCOCC2)c2c1CCC2 +COC(=O)Cn1cc(NS(=O)(=O)c2cccs2)cn1 +CCC(Sc1nccn1C)C(=O)c1ccccc1 +CCc1ccc(NC(=O)Cc2n[nH]c(=O)c3ccccc23)cc1 +O=C(Nc1cccc2cn[nH]c12)c1sccc1C1CC1 +COc1ccccc1N(CC(=O)Nc1ccc(C)cc1)S(C)(=O)=O +O=C(NC1CCN(c2c(F)cccc2F)C1=O)c1ccncc1 +COCC(C)NC(=O)Cn1nc(-c2cccs2)cc(N)c1=O +CN(C)C(=O)N1CCCC(C(=O)Nc2cccc(F)c2)C1 +Cc1cc(C(=O)N2CCCC(C)CC2)nc2c1c(=O)n(C)c(=O)n2C +COc1cccc(CC(NC(C)=O)C(=O)Nc2cccc(OC)c2)c1 +CCn1ccnc(NCc2ccc(OC)nc2)c1=O +Cc1ccc(F)cc1-n1ccn(Cc2ccccc2)c(=O)c1=O +Brc1cnc(NCc2ccncc2)c2ccccc12 +CC(c1ccc(Cl)cc1)N(C)S(=O)(=O)c1cn[nH]c1 +Cn1ccc(NC(=O)N2CCN(c3ccccc3Cl)CC2)n1 +COc1ccc(Nc2cccc(NC(C)=O)c2)c(F)c1 +COC(=O)C(NC(=O)c1cnc2ccccc2n1)C(C)(C)C +CN(CC1CC1)C(=O)CCNS(=O)(=O)c1ccccc1F +c1nc(NC2CCc3ncnn3C2)c2cc[nH]c2n1 +Cn1ncnc1CCNC(=O)NC(CC(C)(C)C)c1ccc(F)cc1 +CNC(=O)c1ccccc1NC(=O)Cc1cccc(OC)c1 +CCc1nnsc1C(=O)N1CCOC(c2ccc(Cl)cc2)C1 +Cc1nc(C(=O)NC(C)c2ccccc2)nn1-c1ccc(F)cc1 +CN(CCc1ccccc1)C(=O)c1sccc1S(C)(=O)=O +Nc1ccn(CC(=O)c2ccc3ccccc3c2)n1 +CCOC(=O)N1CCC(NC(=O)c2c(C)cc(C)[nH]c2=O)CC1 +Cc1ccnn1Cc1nc2c3ccccc3ncn2n1 +CC1COCCN1C(=O)NC(c1ccccc1)c1ccccn1 +COC(=O)c1cc(CSc2nncs2)c(C)s1 +O=C(NCCc1ccc2c(c1)OCCO2)Nc1ccccc1 +CCc1ccc(CN(C)C(=O)c2ccsc2)cc1 +CCc1onc(C)c1NC(=O)c1scnc1C1CC1 +Cc1cccc(OCCCNC(=O)N2CCC(C(N)=O)CC2)c1 +O=C(Cc1ccc(C2CCCCC2)cc1)NCCO +Cc1cc(C)c(NC(=O)CNC(=O)NCC2CC=CCC2)c(C)c1 +NC(=O)c1ccc(N2CCN(C(=O)c3cc4ccccn4c3)CC2)cc1 +Cn1cc(NC(=O)N2CCC(O)CC2)c2ccccc21 +Cc1cc(N2CCCC(c3nccnc3N(C)C)C2)ncn1 +COCCN(C(=O)c1sccc1N)C(C)COC +CCN1C(=O)COC2CN(S(=O)(=O)Cc3ccccc3)CC21 +CCc1[nH]c(C(=O)N(C)Cc2cc(C)on2)c(C)c1C(=O)OC +CCn1c(SC(C)C(=O)N2CCOCC2)nnc1-c1ccccc1 +CCN(Cc1ccc(S(=O)(=O)C(F)F)cc1)Cc1cccs1 +CCOC(CC)C(=O)NCc1cn(-c2ccccc2)nn1 +CCc1nc2n(n1)CCCC2NC(=O)CNC(=O)c1cccc(C)c1 +Cn1cc(CNC(=O)CCC(=O)c2ccc(F)cc2F)cn1 +CCNc1nnc(-c2cccn(CCC(C)C)c2=O)s1 +O=C(OCc1cc(=O)oc2cc(O)ccc12)c1n[nH]c2ccccc12 +CCOc1cccc(-c2nc(C(=O)NCc3ccncc3)cs2)c1 +NC(=O)C(OC(=O)C1CCOCC1)c1ccc(F)cc1 +Cc1cc(S(=O)(=O)NC(C)CO)ccc1Cl +CCNc1nnc(SC(C)C(=O)Nc2cc(F)ccc2F)s1 +COc1ccc(NC(=O)COC(=O)c2ccc(C#N)cc2)cc1OC +COC(=O)c1ccc(N2CCN(C(=O)c3cnccn3)C(C)C2)cc1 +Cc1cccc(-n2ccc(=O)c(C(=O)Nc3c(C)cccc3C)n2)c1 +CC(C)(O)C#Cc1ccc(C(=O)NCc2ccccc2F)cc1 +CCCCCC(=O)N1CCC(C(=O)Nc2cnn(CC)c2)CC1 +COc1ccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c(OC)c1 +CC(NC(N)=O)C(=O)NC(C)c1cccc(OCc2ccccn2)c1 +CC(Sc1nncn1-c1ccccc1)C(=O)c1ccccc1 +Cc1ccc(F)cc1NC(=O)N1CCN(C(=O)CCC(C)C)CC1 +COc1ccccc1N(C)Cc1cc(=O)n2cc(Cl)ccc2n1 +O=C(NCC(O)C(F)(F)F)Nc1ccc(Cl)cc1 +CCCNC(=O)C(C#N)Cc1ccccc1OCC +O=C(CCCOc1ccccc1)Nc1ccccc1 +CS(=O)(=O)N1CCN(C(=O)Cc2ccccc2F)CC1 +O=C(NCC1CCCO1)c1cccnc1OCC(F)F +Cc1cccc(OCCNC(=O)c2ccc(F)cc2F)c1 +Cc1ncsc1C(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +N#Cc1ccsc1NC(=O)CSc1ccc(Cl)cc1 +COC(=O)c1cc(=O)c2c(ccc3oc(=O)ccc32)[nH]1 +CSc1nc(C(C)C)nc(C)c1C(=O)NCCc1ccc(F)cc1 +O=C(Nc1ccc(SC2CCCC2)cc1)C1CCOC1 +Cc1nn(C)c(C)c1CC(=O)N1CCOC2CCCCC21 +Cc1n[nH]cc1CNS(=O)(=O)c1ccc(Br)cc1 +COC(=O)CCC(=O)c1cc(C)ccc1OC(C)C +O=C(CC(C1CC1)C1CC1)N1CCCCC1Cn1cccn1 +CC1CCCC(NC(=O)NCCCN2CCCCCC2=O)C1C +CN(C)c1cccc(CNC(=O)c2cccnc2OCC(F)F)c1 +Cc1cc(NC(=O)CCCc2cc(F)ccc2F)nn1C +CCc1onc(C)c1NC(=O)NCC(C)(C)c1ccncc1 +C#Cc1cccc(NC(=O)c2ccc(-n3ccnn3)cc2)c1 +CNC(=O)c1ccc(NS(=O)(=O)c2ccccc2C#N)cc1 +CC1(C)OCC2(CO1)CN(C(=O)Cn1cnc3ccccc31)C2 +CCOc1ccccc1C(=O)NCC(=O)NCc1ccco1 +Cc1cnn(Cc2cc(C(=O)NCCC3CC4CCC3C4)no2)c1 +O=C(Nc1cccc2cnccc12)c1n[nH]c2ccccc12 +O=S1(=O)COCCN1CC1COc2ccccc2O1 +CC(=O)NCC(=O)Nc1ccc(C)c(Br)c1 +CCOc1cc(C)ccc1S(=O)(=O)NCc1ccccn1 +CN(Cc1cccc(C#N)c1)C(=O)c1cccnc1 +CN(CCCOc1ccccc1)C(=O)C1CCCN1S(C)(=O)=O +CC(C)NC(=O)c1csc(Nc2ccccn2)n1 +O=C(NC1CCCCC1)C1CCN(c2ccccc2)C1=O +CC1CN(C(=O)c2ncn(-c3ccccc3)n2)c2cccnc2O1 +Cn1cc(CN2CCN(c3cccs3)CC2)c(-c2ccncc2)n1 +CC(=O)N(CCC(=O)Nc1ccc(N(C)C)cn1)Cc1ccccc1 +Cc1cccc(NC(=O)C2CCCN(C(=O)N(C)C)C2)c1 +COC(=O)C1CN(CC=Cc2ccc(C#N)cc2)CCO1 +Cc1occc1C(=O)N(C)C(C)Cc1ccc(Cl)cc1 +COc1cc(C)c(C)cc1C(O)CNc1cccc(C(C)=O)c1 +O=C(CNc1cccnc1)c1ccc(Cl)cc1Cl +Cc1nc2ccccc2n(Cc2ccccc2)c1=O +N#Cc1cccc(NC(=O)c2ccc(OCC(F)F)nc2)c1 +CC(=O)N1CCCC(Cc2ccc(-c3ccc(C)cc3)nn2)C1 +O=C(NCCCOc1cccc2cccnc12)c1ccno1 +CCCSc1nnc(NC(=O)NC(C)(C)C)s1 +NC(=O)COC(=O)c1ncc(Cl)c(Cl)c1Cl +COc1cc2nc(C(C)O)n(C(C)(C)C)c2cc1OC +CC(C)N1CCN(C(=O)C2CC(=O)Nc3ccccc32)CC1 +Cc1ccc(C(=O)NC(C)C)c(-n2cnnn2)c1C +COc1ccc(OC)c(C(C)(O)CN(C)c2ccccc2)c1 +CC1Oc2ccc(C(=O)c3nccn3C)cc2N(C)C1=O +C#CCN(CC(=O)N1CCOC2CCCCC21)Cc1ccc(F)cc1 +CC(NC(N)=O)C(=O)NC1(c2ccc(Cl)c(Cl)c2)CC1 +CCOCCCNC(=O)c1cc2c(Cl)ccc3c2n1CCO3 +COc1ccccc1CC(C)N(C)S(C)(=O)=O +Cn1c(C(=O)N2CCCC2)cc2cnc3[nH]ccc3c21 +Cc1nn(C)c2c(NCC(C)C)nc(C3CC3)nc12 +Cc1nnc2sc(COc3ccc(Cl)cc3Cl)nn12 +O=C(Cc1ccc[nH]1)N(Cc1cccc(F)c1)CC1CCCO1 +COC(=O)C1C2C=CC3(CN(Cc4cccs4)C(=O)C13)O2 +COc1ccccc1-c1nn2cccnc2c1CC#N +CCOC(=O)N(C)c1ccc(NC(=O)Nc2cc(C)on2)cc1 +Cc1cnn(CC2CCCN2c2ncnc3sccc23)c1 +CCC1CN(C(=O)CN(C)c2ncnc3[nH]cnc23)CCO1 +COCCN1CC(C(=O)Nc2cc(F)ccc2OC)CC1=O +Cc1cc(NC(=O)c2ccc(-c3nc(C)no3)cc2)[nH]n1 +Cc1c(C(=O)Nc2nnc(C3CC3)s2)oc2c(Cl)cccc12 +CCc1noc(CNc2ccc(F)cc2OC)n1 +Cn1cc(C(=O)NCc2cnn(-c3ccccc3)c2)ccc1=O +COc1ccc(-n2cc(CNC(=O)C3CCCO3)nn2)cc1 +CCCCOc1cccc(C(=O)Nc2nnc(-c3ccnn3C)o2)c1 +CC(=O)NCCNC(=O)C12CC3CC(CC(C3)C1)C2 +NC(=O)C(c1ccccc1)N1CCCC(C(=O)Nc2ccccc2)C1 +NC(=O)CN(C(=O)c1cnc(-c2ccccc2F)s1)C1CCCC1 +COCc1cc(C(=O)N(C)C(C)c2ccc(F)cc2)ccc1F +CN(C)C(=O)c1ccc(CNC(=O)N2CCOCC2C2CC2)cc1 +CCCCN(C)C(=O)c1nn(C)c2c1CSc1ccccc1-2 +CN(C)C(=O)CN(C)C(=O)c1ccc(OC2CCCC2)cc1 +CNc1cc(CNC(=O)c2ccccn2)nc(-c2ccncc2)n1 +Cc1cscc1C(=O)N(Cc1ccco1)CC1CCCO1 +CCc1cc(S(=O)(=O)N2CCC(C(N)=O)CC2)ccc1OC +Nc1nc2ncccc2cc1C(=O)Nc1ccccc1Cl +O=C1CCCc2sc3nc4n(c(=O)c3c21)CCCCC4 +O=c1[nH]nc(SCc2nc(C3CC3)no2)n1CC1CCCO1 +COc1ccc(OC)c(C(C)NC(=O)N(C)CCc2ccccn2)c1 +CN(Cc1nc2sc3c(c2c(=O)[nH]1)CCC3)CC(F)(F)F +NC(=O)C1CCN(C(=O)c2cccc(OCC(F)F)n2)CC1 +CCNC(=O)c1c(C)nc(N)nc1COc1ccc(C)cc1 +CCCOC(=O)C(CC)n1c(C2CC2)nc2c(N)cccc21 +CCn1nc(C)c(NC(=O)c2c(N)cnn2C)c1C +CC(C)Oc1ccc(Cl)cc1C(=O)N1CC(n2cncn2)C1 +CN(C)C(CNCc1cscn1)c1ccco1 +Cc1cccc(CCNc2cc(C)nc3ncnn23)c1 +N#Cc1ccc(COc2cccc3ccc(=O)[nH]c23)cc1 +COc1cc(OC)cc(C(N)c2nc(C)cs2)c1 +CC(OC(=O)c1ccccc1NCCO)C(N)=O +COc1ccc(Nc2ncnc3c2nnn3C)cc1OC +O=C(NCC1CCCO1)c1ccc2c(=O)n3c(nc2c1)CCCC3 +COC(=O)Nc1cccc(NCC(=O)NCc2ccc(Cl)cc2)c1 +Cc1ccccc1CC(=O)N1CCC1c1nc(-c2cccnc2)no1 +O=C(Cn1nc(-n2cccn2)ccc1=O)N1CCc2ccccc21 +CC(CC#N)N(C)C(=O)c1csc(-c2cccc(Cl)c2)n1 +CCn1c(C)cc(C(=O)CSc2nnc(C3CC3)n2C)c1C +CSc1nnc(SCC(=O)NCCc2ccc(F)cc2)s1 +Cc1cc(Br)ccc1OCCOCCN1CCOCC1 +O=C(c1ccc[nH]1)N1CCC2(CC1)OCCCC2O +CCCCN(CC(N)=O)C(=O)c1ccc(Cl)cc1O +CC(Sc1nnnn1C1CC1)C(=O)Nc1cc(F)ccc1Cl +CC(C)(C)n1cc(Nc2nccc(C(F)(F)F)n2)cn1 +CN(C)S(=O)(=O)NC(C)(C)c1ccc(Cl)c(Cl)c1 +O=C(NCCc1ccc(O)cc1)c1cncn1-c1ccccc1 +Cn1cnnc1SCCNC(=O)c1ccc(-n2cncn2)nn1 +CCCNC(=O)c1ccc(CS(=O)c2cccc(Cl)c2)o1 +COc1cc(N)c(CCC(=O)N2CCN(C)CC2)cc1OC +CCNC(=O)c1cc(Cl)ccc1NC(=O)C(C)c1ccsc1 +CCc1noc(C2CCCN(C(=O)c3cnn(CC)c3)C2)n1 +Cc1csc(N(C)C(=O)CCCOc2ccc(Cl)cc2)n1 +CC#CC(=O)NCc1c[nH]nc1-c1ccc(Cl)cc1 +COC(=O)C1(NCc2cccc(Cl)c2F)CC1 +CCCNC(=O)C(N)c1ccc(-c2ccccn2)cc1 +CCC(COC)NC(=O)NC(C)c1cccc(N2CCCC2)c1 +FC(F)(F)c1ccnc(N2CCN(CCc3ccncc3)CC2)n1 +CCc1nc(CNc2c(F)cc(Br)cc2F)no1 +O=C(Nc1ccc(OCC2CCOCC2)cc1)c1ccccn1 +Cc1nc(-c2ccccn2)cc2nn(CC(=O)NC(C)C)c(=O)n12 +Cc1cc(C)n2ncc(CN3CCN4CCN(C)C(=O)C4C3)c2n1 +CCCNC(=O)CNC(=O)c1cn(CC(C)C)c2ccccc12 +C=CCN(Cc1cccs1)C(=O)c1cccc(OC)c1O +CC(=O)NCC1(c2ccc(Br)cc2)CCOCC1 +COc1cccc(OC)c1OCC(=O)Nc1cccc(N)c1 +Cc1nc(N2CCn3cccc3C2C)c2c3c(sc2n1)CCC3 +COC(=O)c1cc(C)ccc1NCc1cccnc1 +CC(C(N)=O)N1CCN(C(=O)c2ccccc2)CC1 +Nc1cnn(Cc2cccc(Br)c2)c1 +CCCNC(=O)c1cccc(C(=O)NC(C)C(C)C)c1 +CCn1c(SCCCO)nnc1-c1ccco1 +COc1ccc(CCCNC(=O)Cn2c(C)c(C)sc2=O)cc1 +CCc1ccc2c(c1)nc(CO)n2CC(=O)N(CC)CC +CCc1ccccc1NC(=O)Cn1nnc(C(=O)OC)c1N +O=C(NCCS(=O)c1ccccc1)NCC1Cc2ccccc2O1 +Nc1cccc(Cl)c1Nc1ccc2c(c1)OCCO2 +CC(=O)NCc1cc2n(n1)CCN(c1ncccc1F)C2 +N#Cc1ccc(CSc2nnc(NC(=O)c3ccco3)s2)cc1 +COc1ccc(C(=O)Nc2cc(C)nn2C2CCCC2)cc1 +O=c1cc(-c2ccc(O)c(F)c2)oc2ncccc12 +Nc1cnoc1-c1ccc2c(c1)CCS2(=O)=O +COc1ccc(OC)c(CN(C(=O)c2cc(C)sc2C)C2CC2)c1 +O=C(NCCc1cc(Br)ccc1F)C1CC2CCC1O2 +CNC(=O)NCC(=O)N(Cc1ccc(F)cc1)CC1CC1 +Cn1nnnc1-c1cccc(NC(=O)Cc2ccc(O)cc2)c1 +O=C1Nc2c(Br)cccc2C2(CCCC2)N1 +CCNc1ncnc(Nc2ccc3c(c2)OCCO3)c1N +O=C(NCCc1c(F)cccc1F)NCc1cscn1 +CCc1c(C)nc2n(c1=O)C(CC(=O)NC(C)CC)CS2 +Cc1cc(NC(=O)CCNS(=O)(=O)c2ccccc2F)n(C)n1 +Cn1cc(C(=O)Nc2cccc(Br)c2)c(C(F)(F)F)n1 +CSc1ccc(C(C)NC(=O)CN(C)S(C)(=O)=O)cc1 +CCOc1ccc(F)c(C(=O)N2CCC3(C2)OCCO3)c1F +CNC(=O)COC(=O)CCCc1c[nH]c2ccccc12 +CC(C)C(CNC(=O)c1coc(-c2ccccc2)n1)N1CCOCC1 +N#Cc1ccc(-c2noc(Cc3cccs3)n2)nc1 +O=C(CCc1ccco1)Nc1cccc(Cl)c1F +Cc1nc2n(Cc3ccccc3F)c3ccccc3n2n1 +COC(=O)CCS(=O)(=O)c1ccc2c(c1)CCC2 +Cc1ccc(OCCOCC(F)(F)F)c(CO)c1 +CCOC(=O)c1cnc(SCC(=O)c2ccc(C#N)cc2)nc1N +Cc1ncsc1CNCc1cccc(OCC#N)c1 +CN1C(=O)c2ccccc2N(C)C1c1ccc(F)cc1 +COC(=O)Nc1ccc(CNC(=O)NCCc2ccccc2F)cc1 +CCOc1ccc(C#N)cc1NC(=O)C(CC)OC +CCc1nnc(NC(=O)Cn2c(=O)c3c(ncn3C)n(C)c2=O)s1 +CC(=O)c1ccc2c(c1)c(=O)oc(=O)n2CCCC#N +Cc1ccccc1OCC(=O)c1cccc(C2OCCO2)c1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccc(-n2ccnc2)nc1 +COCC(C)NC(=O)C1CCCN(c2nc3ccc(C)cc3s2)C1 +COc1ccc(CCNc2nc[nH]c(=O)c2N)cc1OC +CSc1cccc(NC(=O)C2CC(=O)N(C)C2)c1 +COCCN1C(=O)CC2C1CCN2C(=O)c1ccc[nH]1 +CCN(Cc1nonc1C)C(=O)c1cccc(F)c1F +CCc1ccc(NC(=O)NCc2nc(C)cs2)cc1 +CS(=O)(=O)N1CCC(NC(=O)c2c(O)cccc2O)CC1 +O=C(c1cccnc1-n1cncn1)N1CCCCCC1 +CCCCS(=O)(=O)NC1CNc2ccccc2C1 +C#Cc1cccc(NC(=O)CSc2cccs2)c1 +Cc1cc2ccccc2n1CC(=O)N1CCC(C(N)=O)CC1 +CCOC(=O)c1ccc(NC(=O)NCc2ccccc2OC)cc1 +COc1cccc(NC(=O)NCc2nc(-c3ccncc3)n[nH]2)c1 +FC(F)(F)CN1CCOC(c2ccc(Cl)cc2)C1 +CC(C)(C)NC(=O)N1CCOCC1CC(O)c1ccccc1 +COCC12CCCC1CN(c1cc(OC)ncn1)C2 +CCC(Oc1ccccc1)C(=O)Nc1sc(C)c(C)c1C(N)=O +Cc1nc(CN2C(=O)CC3C2CCN3C(=O)N2CCCC2)cs1 +CN(CCc1ccncc1)C(=O)CCc1cccc(N)c1 +CCOC(=O)c1noc2nc(C)nc(N3CCC(C)CC3)c12 +Cn1cc(O)c(=O)cc1CN1CCN(c2ncccn2)CC1 +Cc1ccncc1NC(=O)NCCOCc1ccc(Cl)cc1 +CC1(NS(=O)(=O)CC2CCOC2)Cc2ccccc2C1 +O=C(Cc1c(F)cccc1Cl)Nc1ccccc1O +Cc1ccc(F)c(NC(=O)NCC(=O)NC2CC2)c1 +O=C(Nc1ccc2c(c1)OCO2)c1cc2scnc2[nH]1 +OC(CN1CCN(c2nccs2)CC1)c1ccccc1 +Cc1cccc(COC2COC3(CCCN(c4ncccn4)C3)C2)n1 +COc1cn(-c2ccccc2)nc1C(=O)N1CCOC(C)(C)C1 +CCc1ccc(OC(=O)Cc2ccc(-n3cnnn3)cc2)cc1 +COc1cc(NC(=O)CC#N)c(Cl)cc1Cl +CC(C)C(=O)N1CCC(Cc2nccs2)CC1 +Cc1noc(C)c1CC(=O)NC(C)C1CCCCC1 +CCc1ccc(C(=O)NCC(O)c2cccc(F)c2)o1 +COCC(=O)NC(C(=O)Nc1ccc2oc(C3CC3)nc2c1)C(C)C +COc1cccc(C(=O)Nc2cc(C)c(Br)cn2)c1 +COC(=O)c1sccc1NC(=O)c1cc(F)ccc1C +CC(C)(C(=O)Nc1ccc2c(c1)CC(=O)N2)c1ccc(F)cc1 +Nc1ccccc1NC(=O)CCCSc1ccccn1 +Cc1ccc(C(=O)Nc2ccc3cc[nH]c3c2)cc1 +Cc1oc(C)c(C(=O)Nc2ccc(CS(N)(=O)=O)cc2)c1C +CC(C)(C)OC(=O)NCc1nc(-c2cccc(Cl)c2)no1 +COc1ccc(-c2noc(CNS(=O)(=O)c3ccccc3)n2)cc1 +Cc1csc(NC(=O)c2cc3occc3n2C)n1 +O=C(NCc1ccc(CO)c(F)c1)Nc1nncs1 +CCOc1ccccc1NC(=O)Nc1c(C)noc1CC +CCCn1c(C)nnc1SCC(=O)c1ccc2c(c1)OCCO2 +Cc1nn(C)c(C)c1CC(=O)NCC(C)N1CCc2ccccc21 +O=C(CC1CCOCC1)NCc1ccnc(OC2CCC2)c1 +CC(C)=CC(=O)OCC(=O)Nc1ccc2c(c1)OC(F)(F)O2 +CC(C(=O)NCC1(c2ccc(F)cc2)CC1)c1ccsc1 +COc1c(C(=O)N2CCCC2)ccc2ccccc12 +COCCN(Cc1ccco1)C(=O)NCc1ccc2c(c1)OCO2 +Cc1cccc(Nc2nnc(CC(=O)NCc3ccccn3)s2)c1 +CC(CNC(=O)c1ccco1)Oc1cccc(CN2CCOCC2)c1 +CC(C)NC(=O)C(NC(=O)c1cnn2c1OCCC2)c1ccccc1 +Cc1cc(CNCc2sccc2Br)on1 +Cc1cc(C(=O)N2CCN(c3ccnc(-c4ccccc4)n3)CC2)on1 +COCc1noc(-c2ccc(Oc3ccccc3)o2)n1 +CC(CC(N)=O)Oc1cccc(Br)c1 +CCn1cc(NC(=O)NCCc2cccc(Cl)c2)cn1 +CCC(CC)C(CNC(=O)N1CCCC(CO)C1)N1CCOCC1 +Cc1nnc(-c2cccc(C(=O)NCCCc3cccc(F)c3)c2)o1 +CC(Oc1ccccc1Cl)C(=O)NCc1nncn1C +CCC(CC)N(C)C(=O)c1[nH]nc(C)c1Br +CCC(Sc1nc2ncccc2[nH]1)C(=O)NCCc1ccccc1 +Cc1ccc(NC(=O)NCc2nc(-c3ccccn3)no2)cc1 +Cn1cnnc1SCC(=O)N1CCc2ccccc21 +O=C1CN(c2ccc(NC(=O)c3cc(Cl)c[nH]3)cn2)CCN1 +COc1cc(C)c(C(C)NC(=O)Nc2nnc(C)s2)cc1OC +CCNC(=O)C1CCN(C(=O)c2ccc(SC)cc2)CC1 +N#Cc1cccc(-n2ccnc2C(=O)NC2CCCCC2)c1 +CC(C)C(=O)NCC(C)c1nc2ccccc2s1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)Nc1cc(C)ccn1 +CC(=O)Nc1nonc1-c1nc2ccccc2n1Cc1ccccn1 +N#Cc1ccc(CNS(=O)(=O)c2ccc(C(N)=O)cc2)c(F)c1 +CC(C)(CNC(=O)c1ccc(S(N)(=O)=O)o1)c1ccccc1 +COc1ccccc1CNC(=O)c1cc(=O)c(OC)cn1C +c1nc2c(c(C3CC3)n1)CCN(Cc1ccsc1)CC2 +CC(C)CN1CCOC2CCN(c3cnccn3)CCC21 +COc1ccc(C(=O)NCc2cccc(O)c2)cc1 +CCOc1ccc(F)c(C(=O)N(C)C2(C(=O)OC)CCCC2)c1F +CCOc1ccc(-c2cnn(C)c(=O)c2C#N)cc1 +O=C(COC(=O)c1ccccn1)NCc1ccc2c(c1)OCO2 +Cc1nc(C2CCCN2C(=O)Cc2ccc(F)cc2)ncc1C(N)=O +O=C(Cn1ncc(=O)c2ccccc21)OCC(=O)N1CCCC1 +Cc1cc(C)n2nc(C(=O)Nc3cccc(-c4nnco4)c3)nc2n1 +CC(NC(=O)Cc1nc2ccccc2[nH]1)c1ccc(O)c(F)c1 +O=C(Nc1ccc(C(=O)N2CCC(Nc3ccccc3)C2)cc1)C1CC1 +COc1ccccc1C1CC1NC(=O)c1ccccc1Cl +N#CCCN(Cc1ccco1)C(=O)Nc1ccccc1 +CCC(C)c1ccccc1NC(=O)CS(=O)(=O)c1ccc(C)cc1 +NC(=O)Nc1cccc(C(=O)Nc2ccnn2CCc2ccccc2)c1 +Cn1cc(C2CCCN2c2nn3cc(C(C)(C)C)nc3s2)cn1 +CC(NC(=O)NCC(O)c1ccco1)c1ccc2ccccc2c1 +C#CCN1CCN(CC(=O)N(C)Cc2ccccc2OC)CC1 +CCC(C(=O)N1Cc2cnc(CC(C)C)nc2C1)c1ccccc1 +CCn1cc(-c2ccncc2)cc1C(=O)NCc1cccs1 +O=C(c1ccc(CNc2ccccc2)cc1)N1CCCC1 +CC(=O)NC1CCN(C(=O)c2cc3ccoc3s2)C1 +CN(CC(=O)NC1CC1)C(=O)CNc1cc(Cl)ccc1F +CCOC(=O)C1=C(COC)Nc2ncnn2C1c1ccc(Cl)cc1 +COc1ccnc(N2CCN(C(=O)c3cc(C)no3)CC2)n1 +c1ccc(-c2cccc(CN3CCOCC3C3CC3)c2)nc1 +Cc1nnc(SCC(=O)NC2CCCC(C)C2C)n1N +CCC(C)n1ncc(C(=O)NCCc2c(F)cccc2F)c1C1CC1 +COC(=O)CC1c2cc(OC)c(OC)cc2CCN1CC(C)C +CC(=O)N(C)CC(=O)Nc1cc(C)nn1CCC#N +COc1cc2c(cc1O)C(c1cc[nH]c(=O)c1)NCC2 +CC(C)n1ccnc(NCCS(N)(=O)=O)c1=O +O=C(NCC(=O)N1CCN(c2ncccn2)CC1)NCc1ccco1 +CCN(CCC#N)S(=O)(=O)c1ccc(=O)[nH]c1 +CCc1ccccc1NC(=O)C1CCN(C(=O)c2ccccc2)CC1 +C=CCSc1nc2ccsc2c(=O)n1CC +CNC(=O)c1cccc(NC(C)C(=O)Nc2ccccc2OC)c1 +O=c1[nH]cnc2c1c(-c1ccccc1)cn2-c1ccccc1 +CC(C)(C)c1noc(CCc2nnc(C3CCCC3)o2)n1 +CS(=O)(=O)c1ccc2nc(NC(=O)CC3C=CCC3)sc2c1 +N#Cc1ccccc1Oc1ccc(NC(=O)c2cn[nH]n2)cc1F +CCN(CC)C(=O)CCc1ccc(N2CCCC2)c(N)c1 +CC(=O)Nc1ncc(S(=O)(=O)NCCc2ccccc2)s1 +CCNC(=O)c1ccc(-c2ccc(F)cc2)nc1N +CN(C)C(=O)COc1ccccc1CN1CCC2(C1)OCCO2 +O=C(Nc1ccc(F)c(-n2cccc2)c1)NC1(CCO)CCOCC1 +CC(C)(C)C(=O)NCCCNc1ccc(N)cn1 +NC(=O)Cc1ccc(OCC(=O)N2CCOCC2C2CC2)cc1 +COc1ccc(Cl)cc1-c1c[nH]c(=O)nc1N +Cc1c(C(=O)Nc2ccc(F)cc2F)cnn1-c1ccccn1 +COC(CNC(=O)Cc1cccc(O)c1)c1ccc(F)cc1 +Cc1nc2cc(N(C)Cc3cscn3)c(N)cc2s1 +N#Cc1cccc(S(=O)(=O)Nc2ccc(F)c(Cl)c2)c1 +c1csc(-c2nc(-c3ccc4nncn4c3)no2)c1 +CCOc1ccccc1CNCCc1nc(C)cs1 +CCC(CC)N(C)C(=O)c1ccc(S(=O)(=O)NC)cc1 +Cc1ccc(C2(O)CCN(c3ncnc4nc(C)cc(C)c34)CC2)nc1 +CC1=C(C(=O)Nc2cccc(C)n2)C2(CCCCCC2)OC1=O +COc1ccc(CN2CCN(C(=O)c3c(C)noc3C)CC2)cc1F +O=c1c2cccnc2n(-c2ccccc2)c(=O)n1Cc1ccc(F)cc1 +CC(C(=O)Nc1ccc(Cl)cc1)S(=O)(=O)c1ccccc1 +O=C(NCc1cccnc1)c1nc(Cn2cc(Cl)cn2)no1 +Cc1nc(SCCC#N)c2c(-c3ccccc3)csc2n1 +CC(=O)N(C)c1ccccc1NC(=O)CCC(C)(C)C +CCOc1ccc(C)cc1-c1nc2sc(C3CC3)nn2c1CO +CN(CC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1)C(=O)c1ccccc1 +CC(=O)Nc1ccc(C)c(NC(=O)NCc2ccncc2)c1 +COc1ccc(C(=O)N(C)Cc2nc(-c3ccc(C)cc3)no2)cc1 +O=C(CCS(=O)(=O)N1CCNCC1)Nc1ncccn1 +CCc1nc2c(N3CC4CCC(C3)N(CCOC)C4=O)ncnc2o1 +Cc1cc(Cl)cc2c1OCC(O)C2N1CCOCC1 +Cc1cccc(NC(=O)c2cccnc2N2CCCCC2)n1 +CC(C)(C)C(=O)Nc1n[nH]c2cc(Br)ccc12 +CCC(C)C(NC(=O)c1cc2cc(Cl)ccc2o1)C(N)=O +O=C(CSc1nnc(-c2ccncc2)o1)Nc1cc(F)ccc1F +CCOC(C)C(=O)Nc1ccccc1-c1nnc(C)o1 +COc1ccc(NC(=O)Nc2ccc3c(c2)CCC(=O)N3)cc1 +CN(C)C(=O)CSc1nnnn1-c1cccc(F)c1 +CN(Cc1ccco1)C(=O)c1cc2ccccc2oc1=O +O=C1CCCN1c1ccc(S(=O)(=O)Nc2ccccn2)cc1 +OC(Cc1ccccc1)C1NCCc2ccc3[nH]ccc3c21 +CCn1cnnc1SCC(=O)Nc1cc(Cl)ccc1C +CC1CCCN(C(=O)c2cc3ccccc3oc2=O)C1 +O=C1CCc2cc(S(=O)(=O)Nc3cccc(Cl)c3)ccc2N1 +Cc1cc(C(=O)NCc2cccs2)n(-c2ccccc2)n1 +CCOC(=O)c1c(C)[nH]c(C(=O)N(C)c2ccc(F)c(F)c2)c1C +CCCCC(=O)Nc1nc(-c2ccc3c(c2)N(C)C(=O)CO3)cs1 +CC1(C)CCC(CNC(=O)c2ccc(S(N)(=O)=O)o2)CC1 +Cc1ccc(-n2ncc(C(=O)N3CCOC(C)C3)c2C)cc1 +O=c1cc(N2CCc3ccccc3C2)cnn1C1C=CCCC1 +NC(=O)Cc1csc(NC(=O)c2cccs2)n1 +COc1ccc(CNC(=O)c2ccc(-n3ccc(C)n3)nc2)cc1 +COc1cccc(-c2noc(N3CCN4C(=O)NCC4C3)n2)c1 +Cc1cc(C)nc(CCNC(=O)C2CC(=O)N(C3CCCC3)C2)n1 +COCCOc1ncccc1C(=O)N1CC(C)c2ccccc21 +O=C(Nc1ccccc1O)c1cc(Cl)c2c(c1)OCCO2 +O=C(NCCNS(=O)(=O)c1cccc(Cl)c1)c1ccco1 +O=C(Cc1ccccc1O)Nc1nc2cc3c(cc2s1)OCCO3 +O=C(NCc1ccc(F)cc1)NCC1(O)CCCCC1 +O=C(C(Cc1ccccc1)n1cnnn1)N1CCCC2CCCCC21 +O=c1[nH]nc(CN2CCN(Cc3nc(-c4cccs4)no3)CC2)[nH]1 +O=c1onc(-c2ccccn2)n1CCCc1ccccc1 +CCCCNC(=O)c1cc2cc(OC)ccc2oc1=O +O=C(COC1CCCC1)Nc1nc(C(F)(F)F)cs1 +CCCCOc1ccccc1CN1CCN2C(=O)NCC2C1 +CCCN(Cc1ccccc1)C(=O)c1ccc(F)cc1 +COc1ccc(N(Cc2ccco2)C(=O)Cn2cncn2)cc1F +Cc1nc(COc2cccc(C(=O)NCC3CCCO3)c2)cs1 +Nc1ccc2c(c1)CCN2C(=O)CCc1ccc2c(c1)OCO2 +CSc1cccc(NC(=O)c2ccc(F)cc2F)c1 +N#Cc1ccc(F)c(CNc2cccc3[nH]ccc23)c1 +COCC(NC(=O)CCC1CCCCC1)C(N)=O +O=C(Nc1ccccc1N1CCOCC1)N(CC1CCOC1)C1CC1 +O=C(NCC1CCCO1)c1cncc(-c2ccccc2F)c1 +CCSc1nc(C2CC2)cc(-c2ccco2)c1C#N +COC(=O)CN1CCNc2cc(Cl)c(Cl)cc21 +Cc1cccc(CC(=O)NCCC(O)C(C)(C)C)c1 +Cc1ccc(F)c(C(=O)NCCc2ccncc2)c1 +CSc1nc2nc(C)c3c(=O)n(N)ccc3n2n1 +CC(C)(C)NC(=O)Cc1ccc(S(=O)(=O)CC(F)(F)F)cc1 +CCn1nc(-c2cc(C)c(C)cc2OC)cc(C#N)c1=O +Cc1cc(C(=O)N2CC3OCCN(Cc4ccccc4)C3C2)[nH]n1 +COc1ccc(C(=O)NCCc2cc(C)no2)cc1 +CSc1ccc(S(=O)(=O)N2CCOCC2)cc1 +Cc1ccc2c(COC(=O)c3c(C)noc3C)cc(=O)oc2c1 +Cc1noc(C)c1CCCNC(=O)N1CCc2cc(F)ccc2C1 +CC(C)CC(C)NS(=O)(=O)c1cccc(N)c1 +CCNC(=O)CSc1nnc(-c2cc(C)cc(C)c2)o1 +Cc1cn2nc(N3CCCC3c3noc(C)n3)sc2n1 +Cc1cc(C)n2nc(NC(=O)c3ccccc3F)nc2n1 +CNC(=O)CC(C)N(C)C(=O)Cc1c(F)cccc1Cl +O=C1CCC(C(=O)NCCc2ccc(Oc3ccccc3)c(F)c2)N1 +CCCNC(=O)c1ccccc1NC(=O)c1cc(C)oc1C +CN1CC(c2nc(-c3cccc(Br)c3)no2)CC1=O +N#Cc1nn(-c2ccc(Br)cc2)c2c1CNCC2 +Cc1cc(OCc2cccc(F)c2)nc(-n2nc(C)cc2C)n1 +Cc1cnc(N2CCC3(CC3C(=O)Nc3cccnc3)C2)nc1 +O=C(CCn1ccc2ccccc21)N1CCCCC1 +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)NC(C)C)O2 +c1ccc(-c2nccc(N3CC(n4cccn4)C3)n2)cc1 +Cc1cccc(C)c1NC(=O)CNC(=O)NCC(=O)N1CCCC1 +O=C(Nc1nccs1)C1C(c2ccccc2)C1(Cl)Cl +CCc1ncsc1-c1csc(NCCOC)n1 +CCCC1CCC(NC(=O)Cn2cnnn2)CC1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NCCCN2CCCC2=O)[nH]n1 +CNc1nc2c(s1)C(c1ccsc1)CC(O)=N2 +Cc1cc2c(cc1C)N(C)C(=O)C(c1ccccc1)N2 +O=S(=O)(NCc1cc(Br)ccc1F)c1cccnc1 +Cc1cccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)CCS3)c1 +CC(NC(=O)CN1C(=O)CCOc2ccccc21)C1CCCO1 +COc1ccsc1C(=O)NCCOc1ncccc1Cl +O=C(Cn1cnnn1)N(Cc1ccccc1)c1ccc(Cl)cc1 +O=C(NCC1CC1)c1ccn(COc2cccc(C(F)(F)F)c2)n1 +Cc1cccc(CCCOC(=O)c2cnn(-c3ccccc3)c2C)n1 +CCCc1cc(CN(C)C(=O)CCn2c(C)cc3ccccc32)n[nH]1 +CC(C)c1cc(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)no1 +Cc1cc(CNC(=O)c2cc(COc3ccc(F)cc3F)on2)n[nH]1 +C#CCCN1CCN(C(=O)c2cc(Cl)ccc2O)CC1 +CCC(CC)C(=O)NCC(=O)Nc1c(C)cc(C)cc1C +COc1cc(C)c(C)cc1S(=O)(=O)N1CCCC(C#N)C1 +CCc1[nH]c(C(=O)OCC2(C)COC2)c(C)c1C(=O)OC +CCCC(=O)N1CCCCC1C(=O)Nc1ccccc1Cl +Cc1nc(C)c(C(=O)N2CCCCc3ccccc32)o1 +N#Cc1ccc(NC(=O)c2cc3c([nH]c2=O)CCCC3)cc1Cl +Cc1ccc(CN(C(=O)c2cc(F)cc3[nH]cnc23)C(C)C)s1 +Cc1nc(N2CCCc3ccccc32)nc(C)c1N +COC(C(=O)NCCOc1c(C)cccc1C)c1ccccc1 +O=C(Nc1ccc(-n2cnnn2)cc1)C1CC1c1ccc(F)cc1 +Cn1cncc1C1NCCc2c1cc(F)c(Cl)c2F +Cc1nn(C)c(=O)c(C(=O)NC2(C)Cc3ccccc3C2)c1C +COC(=O)c1ccccc1-c1cc(C)cc2c1OC(CNC(C)=O)C2 +Cc1noc2ncc(C(=O)NCc3ccccc3-n3ccnc3)cc12 +O=C(CSc1ccncc1)Nc1c[nH]cc(Br)c1=O +Cc1nnc(SCC(=O)N2CCCC(C(F)(F)F)C2)n1N +Cc1cc(N2CCN(c3ccccc3)CC2)n2ncnc2n1 +CN(CCc1ccc(F)cc1)C(=O)c1cc(-c2cccs2)n[nH]1 +CCc1cc(C#N)ccc1NC(=O)N1CCCC1COC +O=C(Cc1ccccc1)Nc1cnn(C2CCOCC2)c1 +Cc1ccnc(NC(=O)C2CC(=O)N(c3cc(Cl)ccc3C)C2)c1 +CCOc1ncccc1NC(=O)CNc1ccc(C#N)cc1 +CCCCn1nc(-c2ccc(F)cc2)cc(N)c1=O +CC(Sc1nnnn1C)C(=O)NC12CC3CC(CC(C3)C1)C2 +CCN(CC)C(=O)CNc1ccc2nc(C)sc2c1 +CCN(C(=O)c1cc2c([nH]c1=O)CCCC2=O)C1CCCCC1 +CCCCc1c(C)nn(C(=O)c2ccncc2)c1C +Nc1cc(Cl)ccc1C(=O)N1CCc2ccccc21 +CC(=O)c1cccc(OCC(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1 +CC(=O)N1CCCN(S(=O)(=O)c2c[nH]nc2N)CC1 +C#Cc1cccc(NC(=O)NC2CCCn3nc(CC)nc32)c1 +CC(c1ccccn1)N(C)CCc1ccc(S(N)(=O)=O)cc1 +CCC1CCC(CNC(=O)NCc2cscn2)CC1 +Cc1nc2ncnn2c(N)c1C#CC1(O)CCCC1 +Cc1cc(OCC(=O)Nc2cc(Cl)ccc2F)nnc1C +Cc1nc2ccccc2c(=O)n1CC(=O)Nc1ccccc1F +CCNC(=O)c1ccc(NC(=O)c2c[nH]c3cccc(F)c23)c(C)c1 +CC(CNc1cnc2ccccc2n1)CN1CCCC1=O +CCOC(=O)c1cnn(-c2cc(F)ccc2F)c1N +N#Cc1cccc(CN2C(=O)OCC2C(=O)NCc2cccnc2)c1 +CCn1nc(C)c(CCC(=O)NC2CCCC2)c1C +Cc1cc(C)c(C#N)c(N2Cc3cnc(-c4ccccc4)nc3C2)n1 +CC(=O)Nc1cccc(NC(=O)Cc2ccc(F)cc2)c1 +O=C(Cc1ccsc1)N1CCCCC1c1nc(C2CC2)no1 +CC(=O)Nc1ccc(C(=O)COC(=O)Cc2ccc(F)cc2)c(F)c1 +COc1ccc(CNS(=O)(=O)c2cccs2)cc1NC(C)=O +O=C(COC1CCCC1)Nc1cc(F)ccc1OCC1CCCO1 +COc1ccc2[nH]cc(CNc3ccc(O)cc3)c2c1 +COc1ccc(NC(=O)c2cc3ccoc3s2)cn1 +CCCC1CN(C(=O)CCn2cnc3ccccc3c2=O)CCO1 +COc1ccc(Nc2ncnc3sc4c(c23)CCC4)cc1O +CCc1ccc(S(=O)(=O)Nc2ccccc2C(N)=O)cc1 +CCc1cnccc1C(=O)NC(C(N)=O)c1ccc(F)cc1 +N#CCc1cnn(-c2ccc(F)cc2)c1C(F)(F)F +CSc1ccc(NC(=O)CCN2CCCC2=O)cc1Cl +COc1cccc(Cn2cnc3nc(SC)sc3c2=O)c1 +Nc1nc(SCc2cnoc2)nc2sccc12 +Cc1ccc(CNC(=O)CSc2n[nH]c(N)n2)cc1 +COc1ccc(NC(=O)Cc2nc(-c3ccccc3)n[nH]2)c(OC)c1 +CCCCNC(=O)CCC(=O)N1CC(=O)Nc2ccccc21 +C#CCOc1ccccc1OC(=O)CCn1cc(C)cn1 +N#CC(C#N)CC(=O)c1ccc(C(F)(F)F)cc1 +O=C1Cc2ccccc2N1Cc1ccc2c(c1)OCO2 +O=C(CCCc1ccccc1)N1CCN(CCn2cccn2)CC1 +COc1ccc(CNc2c(C)cccc2O)cc1O +CC(=O)c1ccc(NC(=O)N2CCn3c(nn(C)c3=O)C2)cc1 +O=C(c1ccnnc1)N1CCn2cc(Cn3cccn3)nc2C1 +COc1ccc(-c2ccc3sc(C)nc3c2)cn1 +CC(NC(=O)NC1CCc2cc(F)ccc21)C(=O)NCc1ccco1 +c1ccc(Cn2ccnc2CCNCc2ccsc2)cc1 +CC(=Cc1ccco1)CN1CCN(c2cc(C(N)=O)ccn2)CC1 +COCCCNC(=O)C(C)Nc1cccc(C)c1 +O=C(CSc1nnc2sc3ccccc3n12)N1CCOCC1 +CCOC(=O)c1nnsc1NC(=O)c1ccccc1C +CC(C)CCNC(=O)NCc1ccc(-n2cccn2)nc1 +Cc1ccc(-c2csc3nc(C)nc(NCCCO)c23)cc1 +Cc1cc(-c2nnn(CC(=O)N3CCOC(C)C3)n2)ccc1F +CC(=O)N(C)Cc1cccc(NC(=O)NCc2cccs2)c1 +CCCCCNC(=O)Nc1cccc(C(=O)N(C)C)c1 +CC(C)c1ncc(Cl)c(C(=O)N(C)Cc2cnn(C)c2)n1 +CC1CC(C)CN(C(=O)CSc2nc(N)cc(=O)[nH]2)C1 +Cc1cc(C(=O)CCC(=O)Nc2ccc3c(c2)OCCO3)c(C)s1 +Cc1ccc(CNC(=O)NCc2ncn(C)n2)c(OC(C)C)c1 +CCC1=NC2(CCC(C(=O)Nc3ccc(F)cc3)CC2)C(=O)N1C +Cc1cc(C(=O)Nc2cccn3c(C)nnc23)no1 +CCCNC(=O)NCCC(=O)N1CCN(C)CC1 +O=C(OCCc1c[nH]c2ccccc12)c1cccc(-n2cccn2)n1 +CN(Cc1ccno1)C(=O)c1cnc(Nc2ccccc2)nc1 +Cc1ccc(S(=O)(=O)C2(C(=O)NC3CC3)CCC2)cc1 +Cn1cc2c3c(cccc31)CN(C(=O)C(C)(C)C)CC2 +CCc1nc2c(s1)C(OC(=O)c1ncoc1CC)CCC2 +CS(=O)(=O)N1CCCC12CCN(C(=O)c1ccsc1)CC2 +COC(=O)Cn1cc(NC(=O)Cc2c(C)noc2C)cn1 +Cc1cccc(C(C)CNC(=O)c2cccc(OCC(N)=O)c2)c1 +CC(NC(=O)c1ccco1)C(=O)N(C)CC(=O)N(C)C +O=S(=O)(Nc1ccc2c(c1)OCCCO2)c1ccc(F)cc1 +CC(Nc1ncccn1)c1ccc(-n2cncn2)cc1 +COCCOc1ccc(NC(=O)N(C)C(C)CC#N)cc1 +COc1ccc(-c2noc(-c3ccccc3C(=O)N(C)C)n2)cc1 +CCCN(CCc1cccc(F)c1)Cc1ccon1 +O=C(NCC(=O)N1CCc2cc(-c3ccno3)ccc21)c1ccccc1 +COC(=O)c1sccc1CN1CCOC(c2ccccc2F)C1 +CCc1ccccc1NCc1cc(C(N)=O)ccc1F +CC(C)Cn1cc[nH]c1=NC(=O)c1cc(Br)c[nH]1 +Cc1cc(N(CCC#N)CCC#N)ccc1Br +O=C(Nc1ccc(CCC(=O)N2CCCC2)cc1)c1cc(Cl)c[nH]1 +CC(C)(C)C1CCCCC1NC(=O)C1CCCN(S(C)(=O)=O)C1 +CS(=O)(=O)NC1CCN(C(=O)c2cccc(F)c2)C1 +Cc1nn2cccnc2c1C(=O)NCCc1ccccc1F +CCc1ccc2c(c1)cc(C)c1nnc(SCC(N)=O)n12 +c1ccc(-c2cc(-c3nnc4sc(-c5ccco5)nn34)[nH]n2)cc1 +CCOc1ccc(C(=O)CN2CCOCC2)c(C(C)C)c1 +CC(C)n1nc(C(=O)N2CCC(=O)CC2)c2ccccc2c1=O +Cc1noc(C)c1CCC(=O)NC1C2CCCOC2C1(C)C +CC(Sc1nnc(C(F)(F)F)n1N)C(=O)N(C)CCC#N +COc1cc2c(c(Br)c1OC)CCNC2 +Cc1cc(C(=O)N2CCCCC2)c2ccccc2n1 +OC1CCCN(c2cc(Br)ccn2)C1 +CCOCC1CCCN(C(=O)c2nccc3ccccc23)C1 +CCCNC(=O)C1CCCN(S(=O)(=O)c2ccc(F)cc2)C1 +CC(=O)N(Cc1ccc(NC(=O)C2CC=CC2)cc1)C(C)C +Cc1ccc(CCC(=O)Nc2cc(-c3ncco3)ccc2C)o1 +CC(=O)c1[nH]c(C)c(C(=O)NCc2cn3c(C)c(C)sc3n2)c1C +CSc1nsc(NC(=O)Cc2cc(F)ccc2F)n1 +NS(=O)(=O)Cc1ccc(NS(=O)(=O)c2ccccc2F)cc1 +CCc1onc(C)c1NC(=O)CSc1ccc(C#N)cc1 +NC(=O)C1(NCC(F)(F)F)Cc2ccccc2C1 +CCn1ccnc(NCc2cnn(-c3ccccc3)c2)c1=O +CCc1ccc(NC(=O)CCNC(N)=O)cc1CC +COc1ccc(C)nc1NC(=O)c1cccc(C2OCCO2)c1 +CCCNC(=O)c1cc(-c2csc(C)n2)cn1C +Cc1cc(C(=O)Nc2cc(S(N)(=O)=O)cc(C)c2C)no1 +CCCOc1ccc(C2NC(=O)c3ccccc3N2)cc1OC +O=C1CC2(CCN(S(=O)(=O)C3CCCCC3)C2)Oc2ccccc21 +CN(Cc1ccco1)C(=O)NCc1cc(Br)cs1 +CC(C)CN(CC(F)(F)F)C(=O)CN1CCOCC1 +COCCN(C)C(=O)c1cc(S(N)(=O)=O)ccc1OC +O=C(c1ccc2occc2c1)N1CCN(Cc2cccc(F)c2)CC1 +CC(=O)N1CCc2cc(NC(C)C(=O)Nc3ccc(F)cc3)ccc21 +CCC(NC(=O)C1CCOCC1)c1ccccc1OC +CC(C)OCc1cccc(CNC(=O)c2ccco2)c1 +Cc1c(C(=O)NCC2CCCO2)nnn1-c1ccc(Cl)cc1 +CCc1noc(CC)c1CNC(=O)NC1CCc2cc(F)ccc21 +Cc1ccc(S(=O)(=O)N2CCc3sccc3C2)cc1 +COc1ccc(NC(=O)c2cc(-c3ccccc3Cl)on2)cn1 +O=C(Nc1cccc(OC(F)(F)F)c1)C1CCOC1 +CC1CN(C(=O)Cc2ccc(F)c(F)c2)c2ccccc2NC1=O +COc1ccc(CN(C)C(=O)c2cccnc2OC)cc1F +Cc1oc(C(=O)OCc2ccsc2)cc1S(=O)(=O)N(C)C +CCC(C#N)OC(=O)c1ccc(CCNC(N)=O)cc1 +CC(=O)N1Cc2ccccc2CC1C(=O)Nc1ccc(C)cc1Cl +COCCN(Cc1ccccc1Cl)C(=O)C1CCCN1C(N)=O +CCN(Cc1cccc(NC(=O)CCc2ccccc2O)c1)C(C)=O +COc1ccc(CNc2c(C)cccc2C)cc1O +C=CCn1cnc2c(Cl)cc(-c3ccc(C(=O)NC4CC4)o3)cc21 +CCC(COC)NC(=O)c1c[nH]nc1-c1ccccc1F +COc1cc(N)ccc1NC(=O)c1ccc(Cl)cc1O +C=C=Cn1c(C2CC(=O)N(c3ccc(C)cc3C)C2)nc2ccccc21 +CCOC(C)C(=O)Nc1ccc(Cl)cc1C(=O)OC +NC(=O)c1ccc(C(=O)OCCc2cccnc2)cc1 +CC(O)CNC(=O)c1cc(-c2ccncc2)nc2ccccc12 +CCN(CC)C(=O)CNc1ccc(C)c(NC(C)=O)c1 +O=C(NCc1ccc(F)cc1)c1cc2cccnn2n1 +C=C(C)CN1C(=O)C2(OCCO2)c2cc(Br)ccc21 +O=C(Cc1ccsc1)N1Cc2nc(-c3ccccc3)sc2C1 +Cc1cc(C(=O)NCc2ccc(Cl)cc2Cl)[nH]n1 +Cc1c(NC(=O)NCCNc2ncccn2)cccc1OC(F)F +CCCOC(=O)c1cc(-c2ccc(S(=O)(=O)CC)cc2)nn1C +CC(C)(C)NS(=O)(=O)c1ccc(NC(=O)C2CCCO2)cc1 +CCc1ccc(NC(=O)CSc2nnc3nc(C)cc(C)n23)cc1 +Cn1c(COC(=O)c2cc3c(s2)CCC3)cc(=O)n(C)c1=O +CCN(C(=O)c1cc(C)nn1C)c1cc(C)ccc1C +CC(C)C(CNC(=O)Cc1ccc(-n2cnnn2)cc1)c1ccccc1 +N#Cc1cc(NC(=O)c2ccncc2F)ccc1OCC(F)(F)F +O=C1CN(C(=O)Cc2csc(Nc3ncccn3)n2)CCN1 +CN(C)c1cc(OC2CCN(S(=O)(=O)c3c[nH]cn3)C2)ncn1 +N#CCc1ccc(NC(C(=O)NC2CC2)c2ccccc2)cc1 +Cc1cc(C)c(CNc2c(Cl)cccc2C#N)c(=O)[nH]1 +COc1cccc(CNC(=O)Nc2cnccc2C)n1 +O=C(c1ccccc1F)N(CC1=CC2=CC=NC2C=C1)C1CC1 +COc1cc(C)c(S(=O)(=O)N2CCC(C)CC2)cc1C +Nc1ccc(Cl)cc1-c1nnc(N2CCOCC2)o1 +Cc1cc(C)c(CNC(=O)N2CCN(CC(N)=O)CC2)c(=O)[nH]1 +Cc1cnc(N)nc1N1CCC(C(=O)NC2CCCCCC2)CC1 +CC(C)c1ccc2c(c1O)C(=O)CC1C3=C(CCC21C)C(=O)OC3 +O=C(N1CCCN(c2nccs2)CC1)C1(c2cccc(F)c2)CC1 +COc1cc(CC(=O)Nc2cc(C)cc(C)c2)cc(OC)c1OC +Cc1cccc(C2NCCc3ccc(C)c(F)c32)n1 +Cc1ccc(-c2noc(CNC(=O)C(C)C)n2)cc1 +O=C(Nc1cccc(N2CCCC2=O)c1)C1CC=CCC1 +CN1CCN(C(=O)c2n[nH]c3c2CCN(Cc2ccoc2)C3)CC1 +COc1ccc(C(O)CCNc2cccc(C)c2)cc1 +Cc1cccc(C)c1NC(=O)CC1NCCc2ccccc21 +CCS(=O)(=O)N1CCN(C(=O)Nc2cccc(SC)c2)CC1 +COc1ccc(OC)c(C(C)NC(=O)C2CCOCC2)c1 +O=C(NCc1noc(-c2cccs2)n1)c1coc(C2CC2)n1 +NC(=O)c1ccc(S(=O)(=O)NCc2cscn2)cc1 +COc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1OC +Nc1ccc2c(c1)N(CCc1ccccc1)CCS2 +CCC1COCCN1C(=O)c1cccc(NC(C)C)c1 +OCc1nnn(Cc2cccc(F)c2)c1-c1ccco1 +CCCn1c(C)cc(C(=O)CSc2ncnc3sccc23)c1C +CCCc1nc2cc(OC)c(OC)cc2n1CC#N +CCCCn1c(C(C)NC(=O)c2cccnc2)nc2ccccc21 +CN(C(=O)c1ccccc1NC(=O)C1CCOCC1)C1CCCCC1 +Cc1ccccc1C(=O)Nc1cnc2ccccn2c1=O +Cn1nnnc1SCCCC(=O)Nc1cccc(N)c1 +COC(=O)C(CO)NC(=O)c1cn2ccccc2n1 +CC(=O)Nc1cccc(CNC(=O)N(C)CCC(F)(F)F)c1 +Cc1cc(NC(=O)NC(C)c2ccc(Br)cc2)n(C)n1 +COC(=O)C1CC(NC(=O)c2ccc(OC)cc2)CN1C(C)=O +CS(=O)(=O)NCc1ccccc1N1CCOCC1 +COc1ccc(OC)c(C2CCCN2C(=O)c2ccc(C)[nH]c2=O)c1 +Cc1nn(C)c2ncc(C(N)=O)c(Oc3cccnc3)c12 +CC(=O)Nc1cc(S(=O)(=O)N=c2[nH]cccc2C)ccc1C +Cn1c(C(F)(F)F)nn(CC(=O)Nc2cc(F)ccc2F)c1=O +Cc1csc(C(C)NC(=O)N2CCN(c3ncccn3)CC2)n1 +CCOC(=O)c1ccc(CN2CCOC(c3cccc(OC)c3)C2)o1 +Cc1ccc(C(=O)N(CCO)C2CCCC2)cc1F +COc1cccc(C(=O)N2CCCC(c3nc(C)no3)C2)c1F +Cc1cnn(CC2CCCN2C(=O)c2ccc3c(c2)COC3)c1 +CCC(=O)Nc1cc(NC(=O)COc2ccccc2)ccc1C +Cc1[nH]nc(C(=O)NCCc2cccs2)c1N +Cc1ccc(-c2nc(CC(=O)N(C(C)C)C3CCOCC3)cs2)o1 +Cc1ccc(-c2n[nH]c(SCCCC#N)n2)cc1 +CCC(C)OCC(=O)NC1CCCN(c2ccccc2F)C1=O +CC(=O)Nc1cc(NC(C)=O)cc(-c2nc3ccccc3[nH]2)c1 +COC(=O)CSc1nnc(-c2ccc(Br)cc2)o1 +CCCCN(C(=O)Cc1ccc(C)nc1)c1ccccc1 +CC(=O)c1ccc(NC(=O)CN(CCc2ccccc2)C(C)=O)cc1 +C=CCN1CCN(C(C)C)C(=O)C12CCN(C(=O)COC)C2 +CC1CCCCN1C(=O)Cn1ncc(Cl)c(Cl)c1=O +O=C(Cn1ccccc1=O)Nc1ccc(-n2cncn2)c(F)c1 +Cc1cccnc1C(C)NC(=O)c1cccc(Cn2cccn2)c1 +CC(Sc1ccccc1)C(=O)NCC(O)c1ccc(Cl)cc1 +O=C1CCCc2c1cnn2-c1nc2ccccc2s1 +Cc1ccsc1C(=O)Nc1cccc(N2CCNC2=O)c1 +COc1ccc(CN(C)Cc2nnc(C)n2C)c(Cl)c1OC +CC(=O)N1CCN(c2ccccc2CNc2ccc(CC#N)cc2)CC1 +Cc1ccc2ncc(C(=O)N(C3CC3)C(C)c3ccco3)n2c1 +O=S(=O)(c1ccc(-c2nc(-c3ccccc3)no2)o1)N1CCCC1 +CCc1cc(-c2ccc3c(c2)OCCO3)ccc1NC(C)=O +CC(=O)c1cccc(NC(=O)c2cc3cc(F)ccc3n2C)c1 +CCN(c1cccnc1)S(=O)(=O)c1c(C)sc2ccccc12 +Cc1nnsc1C(=O)Oc1ccc(Cl)cc1 +Cc1nc(COc2ccc(C(=O)Nc3ccncc3)cc2)cs1 +NC(=O)C1(NC(=O)c2cc(-c3ccccc3)no2)CCCCC1 +OCCCn1c(-c2ccccn2)nc2cc3c(cc21)OCCO3 +CCOc1ccccc1NC(=O)COC(=O)c1cccc(O)c1 +CCNc1cc(C)nc(N2CCN(C(=O)c3cccs3)CC2)n1 +CCOC(=O)COc1ccc2c(c1)C(=O)CC(C)(C)O2 +Cc1ccc(C)c(CC(=O)Nc2cccnc2-n2ccnc2C)c1 +CCC(C)NC(=O)c1ccc(NC(=O)c2ccn(C(C)C)n2)c(C)c1 +c1ccc(COc2ccnc(-n3ccnc3)n2)cc1 +Cc1nc(NC(=O)c2cncc(Br)c2)sc1C +COCC(C)N1CCN(S(=O)(=O)N2CCCCC2)CC1 +Cc1nccc(CNC(=O)C(N)c2ccccc2)n1 +Nc1c(Cl)cccc1C(=O)NCc1ccc(Cl)cc1 +Cc1ccc(NC(=O)CCCN2C(=O)COc3ccc(C)cc32)cc1 +COCc1cc(N(CC2CCOC2)C2CC2)n2ncnc2n1 +Cc1nnc(N2CCCC3(CN(C(=O)c4ccno4)CCO3)C2)o1 +Cc1ccc(C(=O)Nc2c(C)cccc2C(=O)N2CCCC2)c(C)c1 +NC(=O)N1CCCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1 +Cc1ccc2nc(C)c(C)c(C(=O)NCCNc3cccnc3)c2c1 +CCCc1cc(C(=O)N2CCN(Cc3cc(C)on3)CC2)[nH]n1 +CC(C)CCNC(=O)c1cc(F)c(F)c(F)c1F +Cc1cc(C)c2c(CC(=O)N3CCC(CO)C(O)C3)coc2c1C +CC(C)NC(=O)CCc1ccc(S(=O)(=O)N2CCCCC2)cc1 +COCCN(Cc1cccs1)C(=O)c1cnc2ccccn2c1=O +CCc1cc2c(c(C(O)Cc3cccs3)c1)NC(=O)CC2 +Cc1cc(C)c2c(n1)SCC(=O)N2CC(=O)NC1CCCCC1C +Cc1cc(NC(=O)COc2cccc(Oc3ncccn3)c2)no1 +Cc1nn(C)c2nc(N(CCCO)Cc3ccc(F)cc3)sc12 +O=C(c1cccc(-c2ccoc2)c1)N1CCC(n2cncn2)CC1 +Cc1cc(C)n2nc(CC(=O)N3CCCCC3C(C)C)nc2n1 +Cn1c(C(=O)NCCc2ccco2)cc2c(F)cccc21 +O=C(CC1Sc2ccc(Cl)cc2NC1=O)OCC(F)F +O=C(NCc1ccccc1)c1nc(-c2ccccn2)cs1 +O=C1COc2ccc(-c3csc(-c4ccccn4)n3)cc2N1 +COc1ccc(CCN2CCN(C(=O)C(C)NC(N)=O)CC2)cc1 +Cc1noc2ncc(C(=O)NC3CCC(C(F)(F)F)CC3)cc12 +CC(CNC(=O)Cn1c(=O)n(C)c2ccccc21)c1cccs1 +COc1ccc(Cn2cccc2-c2nc(-c3ccncc3)no2)cc1 +CC(NC(=O)N1CCC(OCc2ccccc2)CC1)c1nncn1C +N#Cc1c(-c2ccccc2)cc(-c2ccccc2)n(N)c1=O +Cc1n[nH]cc1CNS(=O)(=O)c1cccc(F)c1 +CN(C)C(=O)N1CCC2(CCCN(C(=O)Cc3cccnc3)C2)C1 +CCOC(=O)Nc1ccc(NC(=O)c2c(C)nsc2NC)cc1 +O=C(CCC1Cc2ccccc2NC1=O)NCc1ccc(F)cc1 +O=C(Oc1ccccc1)C1CCCN(C(=O)Cc2ccc(F)cc2)C1 +Nc1c(NCc2ccccc2)ncnc1OC1CCCCC1 +CNC(=O)C(NC)c1ccc2c(c1)NC(=O)C(C)O2 +Cc1cc(CN(Cc2cc(C)n(C)n2)c2ccccc2)nn1C +Cc1ccccc1OCCN(C)C(=O)C1CC=CC1 +CC(=O)NCCNC(=O)NC1CC(=O)N(c2ccc(F)cc2)C1 +Cc1nc(C2CCN(C(=O)c3ccc[nH]3)CC2)cc(=O)[nH]1 +COCC(=O)n1nc(-c2cccs2)nc1NCc1cccs1 +Cc1ccc(C(C)NC(=O)c2c(-c3ccccc3)noc2C)o1 +Cc1cccc2c(=O)n(Cc3cccc(C#N)c3)cnc12 +COC(=O)N1CCC(CNC(=O)COc2ccc(Cl)cc2)CC1 +Nc1cccc(NC(=O)COc2ccc(Cl)cc2)c1 +COCc1nn2c(-c3ccncc3)ccnc2c1-c1ccccc1 +COCCN1CCN(C(=O)NC2C3Cc4ccccc4C32)CC1=O +CN(C(=O)c1cc2c(=O)n(C)c(=O)n(C)c2s1)c1ccc(F)cc1 +Cc1cc(O)c2c(c1)C(c1ccc(F)nc1)NCC2 +COC(=O)c1nccc2c(Br)c(F)ccc12 +Cc1ccc(C(NC(=O)c2cccc(-n3cnnn3)c2)C2CC2)cc1 +O=C(Cn1ccccc1=O)NC1CCc2c(F)cccc21 +O=C(C1CCCC1)N1CCC(c2cc(C(F)F)n3ncnc3n2)CC1 +CCN(CC)C(=O)Nc1ccc(OC)c(-n2nnnc2C)c1 +Cc1c(C(=O)N(Cc2ccco2)CC2CCCO2)oc2ccccc12 +COCCNC(=O)C(N)c1cccc2ccccc12 +CCCCNC(=O)c1cc2c(C)nn(C(C)(C)C)c2nc1N +CNc1cc(C(=O)NCC2(Cn3nc(C)cc3C)CC2)ccn1 +O=C(Cc1ccc(F)cc1)NC1CCN(c2c(F)cccc2F)C1 +COc1ccc(CC(=O)NCCNC(=O)c2ccccc2O)cc1 +Cc1cc(F)ccc1C(=O)N1CCC(OCc2ccccc2F)CC1 +CC1CC1CNC(=O)CCCc1nc(-c2cccs2)no1 +Cc1ccccc1NC(=O)Cn1cc(-c2ccccc2)cn1 +O=C(NCCCCN1CCOCC1)NC1(c2ccccc2)CCCC1 +CCCc1nnc(NC(=O)c2ccc(-c3cccs3)nc2C)s1 +CC(C)OC(=O)c1cn(-c2cccc(Cl)c2)c(=O)c2ccccc12 +COCCNC(=O)NCC#CCOc1cccnc1 +COc1cc(C(=O)Nc2cccc(C(C)O)c2)cc(OC)c1OC +CC(C)n1nccc1NC(=O)N(C)Cc1nc2cc(Cl)ccc2[nH]1 +CCC1CCC(NC(=O)C2CCN(S(=O)(=O)CC)CC2)CC1 +CC(C)(CNS(=O)(=O)c1ccccc1)c1ccc2c(c1)OCCO2 +CCC(=O)Nc1ccc(-c2nc3ncccc3o2)cc1 +Cc1nn(C(C)C(=O)NCc2cccnc2)c2ccccc12 +COCCCNC(=O)CNc1cc(Br)ccc1Cl +CCC(C(=O)N1CCCCC1)n1c2ccccc2c2cn[nH]c(=O)c21 +COc1ccc(NC(=O)CSc2nnc3nc(C)cc(C)n23)cc1 +Clc1ccc(Cc2noc(-c3ccnnc3)n2)cc1 +CCCOc1ccc(NC(=O)NCc2ccccn2)c(C)c1 +Cc1ccc(Cl)cc1S(=O)(=O)NCCNC(=O)C(C)C +O=C(Nc1cccnc1)C1CCCN1C(=O)c1cccs1 +O=C1CSc2ccc(C(=O)Nc3cc(Cl)ccc3O)cc2N1 +CC1(C)CNC(=O)c2nc(-c3nc(-c4ccccc4F)no3)[nH]c2C1 +O=C(Nc1ccc2ccccc2n1)C1CC=CCC1 +CCN(C)c1cccc(NCc2c(C)nn(C)c2OC)c1 +COc1cccc(CCC(=O)Nc2cc(-c3ccn[nH]3)sc2C)c1 +CCC(C)N1C(Cl)=Nc2ccccc2S1(=O)=O +CCCc1ncc(-c2csc(NCCOC)n2)s1 +O=C(NC1CC(=O)N(c2ccc(Cl)cc2)C1)c1ccco1 +O=C(Cc1ccc(O)cc1)Nc1ccc(-c2cn3ccsc3n2)cc1 +CCOC(=O)NCCOc1cc(N2CCCC2)nc(C)n1 +CCn1c(SCCOC(C)C)nnc1-c1ccncc1 +O=C(OC(C(=O)NCC1CCCO1)c1ccc(F)cc1)c1ccco1 +Cc1ccc(C)c(NC(=O)Cc2cn3ccsc3n2)c1 +COc1ccc(-c2cnc(Cn3nccc3-c3ccncc3)o2)cc1 +COC(=O)N1CCC(CNC(=O)c2ccc(F)cc2F)CC1 +O=C(Cc1c[nH]c2ccccc12)N1CCc2[nH]ncc2C1 +CCC1c2ccsc2CCN1C(=O)C1CC(=O)Nc2ccccc21 +Cc1nc2c(cc1C(=O)NCC1CCCO1)c(C)nn2C +Cc1nc(CC(=O)NCCc2ccccn2)cs1 +CCOC1CCN(C(=O)C(c2cccc(F)c2)N(C)C)CC1 +Cn1ncc(Br)c1NC(=O)Nc1ccccc1 +Cn1c(=O)c2c(c(-c3ccccc3)cn2C)n(CC#N)c1=O +Cc1noc(C(=O)N2C(C)CCCC2C)c1Cl +Cc1[nH]c(=O)[nH]c(=O)c1CCc1nnc(SCc2ccccc2)o1 +CCC(CC)c1cc(CNC(=O)Nc2cccc(NC(C)=O)c2)on1 +O=C(Nc1ccc2c(c1)COC2)NC1(c2cccc(F)c2)CC1 +CCCN(Cc1nnc(-c2ccccc2Cl)o1)C(=O)COC +CC(=O)NC(C(=O)Oc1cccc(Cl)c1)C1CCCC1 +Cc1ccc(C)c(C(=O)CSc2nnnn2C(C)C)c1 +Cc1nc(C(=O)Nc2ccc(Cl)cc2Cl)co1 +C=CCn1c(SCC(=O)Nc2nccs2)nnc1-c1ccco1 +CC(C)N(C1CCC1)S(=O)(=O)c1ccc(Cl)cc1F +O=C1CCCc2nc(N3CCc4ccccc4C3)ncc21 +CCCNC(=O)CCNC(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +CN(c1ccc(F)c(F)c1)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +CN(C(=O)CN(c1cccc(Cl)c1)S(C)(=O)=O)C1CC1 +CC(Cc1ccccc1F)NC(=O)NCc1ccc(O)cc1 +CCc1onc(C)c1NC(=O)c1csc(-c2ccccc2OC)n1 +O=C(CSc1nncs1)c1ccc2c(c1)CCC2 +COc1ccc(NC(=O)CNC(=O)c2cccs2)c(OC)c1 +Cc1ccc(NC(=O)c2nc3c(s2)CCCN3C(C)C)nc1 +CN(C)C(=O)N1CC(OCc2ccccn2)C2OCCCC21 +Cc1nc(CSc2nnc3n(C)c4ccccc4n23)sc1C +CNC(=O)c1cn(-c2ccc(NC(C)=O)cn2)cn1 +CC1Cc2cc(-c3c(-c4ccccc4)ncn3CCCO)ccc2O1 +CNC(=O)N1CCN(c2ccc(Br)cn2)CC1 +CCOc1ncccc1CNS(=O)(=O)N1CCCCC1 +COc1ccc(-c2c(N)ncnc2C(F)(F)F)cc1Cl +CC1=NC(=O)C(CCC(=O)Nc2cc(C)ccc2C)C(C)=N1 +O=C(Cc1cccs1)Nc1nnc(CCc2ccccc2)s1 +CC(C(=O)NC1CCCN(c2ccccc2F)C1=O)c1cccs1 +CC(NC(=O)Nc1cc(F)ccc1F)C(=O)NC(C)(C)C +CCC(C)C(=O)NCC(=O)NC(C)c1ccccc1Cl +Cc1nc(CNC(=O)N2CCOCC2C2CC2)oc1C +COC(=O)c1c(NC(=O)c2cc(C)on2)sc2c1CCC(C)C2 +CC(C)c1csc(NC(=O)c2cccc(N(C)C)c2)n1 +c1cncc(-c2n[nH]c(SCc3nnc(-c4cccs4)o3)n2)c1 +Cc1cccc(S(=O)(=O)N(C)c2cccc(O)c2)c1 +CCN(CC(=O)NCC(=O)N(C)C)c1ccccc1 +Cc1cc(C(C)NC(=O)N2CCOCC2C)c(C)s1 +CCn1cnnc1CNC(=O)CCOc1cccc(C)c1C +Cc1c[nH]c(C(=O)N2CC(CO)C(CN3CC(C)OC(C)C3)C2)n1 +Cc1nc(N(C)C)nc(-c2cccc(-c3cc[nH]n3)c2)c1C +Cc1cc(NC(=O)Cc2csc(NC(=O)c3ccco3)n2)[nH]n1 +O=c1[nH]nc(SCCOc2ccccc2F)n1CC1CCCO1 +CCC(Nc1n[nH]c(=O)[nH]c1=O)C1CCCCC1 +CC(Cc1cccnc1)n1cnc2cccc(Cl)c2c1=O +Nc1cc(F)c(F)cc1NC(=O)c1ccc(F)c(F)c1 +CCCCNS(=O)(=O)c1cc(OC)ccc1OC +O=C(Nc1cnn(-c2ccccc2F)c1)c1cc2ccccc2[nH]1 +Nc1c(OC2CCCCC2)ncnc1N1CCCCCC1 +CCOC(=O)NCCC(=O)N1CCn2cccc2C1C +Cn1cc(C(=O)NCc2ccccn2)c2ccccc21 +CCC(=O)Nc1ccc(NC(=O)CCC(C)C)cc1 +COCCOCC(=O)N(C)Cc1ccc(Cl)cc1 +COCc1ccc(C(=O)NCC2(N3CCOCC3)CCCCC2)cc1 +C#CCOc1ccccc1CN1CCOC(c2cccs2)C1 +O=S(=O)(c1ccc(Nc2ccc(F)cc2)nc1)N1CCCC1 +O=C(CO)N1CCN(CC(=O)N(Cc2ccccc2)C2CC2)CC1 +O=C(Cn1cccn1)c1ccc(Oc2ccccc2)cc1 +CCNC(=O)Nc1cc(C(F)(F)F)ccc1-n1cccn1 +CC(C)Oc1cccc(CNC(=O)NC2CCC(O)CC2)c1 +CCc1ccc(NC(=O)CCCCNC(N)=O)cc1 +CCOCc1ccccc1NC(=O)NCc1ncc(C)c(OC)c1C +COCC(=O)Nc1ccc(-c2cc(OC)cc(OC)c2)cc1 +Cc1cc(OCC(=O)N(CCC#N)Cc2ccco2)ccc1Cl +Cc1nn(C)c(C)c1CC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CCNC(=O)CSc1nnc(-c2ccc(OC)cc2)o1 +O=C(Cc1ccc(F)cc1F)NCC(=O)OCc1ccccc1 +CC(C)(C)OC(=O)N1CCN(Cc2nncn2-c2ccccc2)CC1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)NCC2CCCCC2)c1C +NC(=O)CCc1nc(-c2ccco2)nn1-c1cccc2c1CCC2 +Cc1c(C(=O)N2CCNC(=O)C2)sc2nc[nH]c(=O)c12 +CC(Sc1n[nH]c(N)n1)C(=O)c1ccc2c(c1)NC(=O)CO2 +COC(=O)C1CCCCCC1NC(=O)CC(C)C +CC1=C(c2ccc(F)cc2)S(=O)(=O)N=C1NCc1ccccc1F +NC(=O)C1CCN(C(=O)Nc2cccnc2-n2cccn2)CC1 +CC(C)(CO)Nc1nc2nonc2nc1N1CCCCCC1 +CC(Sc1nncn1-c1ccccc1)C(=O)Nc1ccccc1 +CCN(C(=O)c1cnn(CC(C)C)c1C(F)F)c1ccc(C#N)cc1 +N#Cc1nnn(-c2nccs2)c1Cc1ccc(Cl)cc1 +N#Cc1c2n(c3c(NCc4ccccc4)ncnc13)CCCC2 +O=C(NCCCOc1ccccc1)c1csc(-c2ncccn2)n1 +Cc1nc(CNC(=O)Cc2c[nH]c3ccc(Cl)cc23)oc1C +CCC(C)NC(=O)Cc1nc(-c2ccncc2)n[nH]1 +CN(C(=O)NC1CCCc2c1cnn2CCO)c1ccccc1F +CCOCC1CCCN(C(=O)c2sccc2CC)C1 +CC1(C)Cc2cccc(CN3CCOC(C(N)=O)C3)c2O1 +COc1cc2nc(C)sc2cc1NC(=O)C(C)NC(N)=O +COc1ccccc1CC(=O)Nc1ccc(C#N)cc1 +C=CCNC(=O)c1n[nH]c2c1CN(C(=O)Cc1ccc(C)cc1)CC2 +CCNC(=O)CNC(=O)CCC(=O)c1ccc(F)c(F)c1 +CCOc1ccc(CNC(=O)Nc2cc(C)ccc2OC)cc1OC +CNC(=O)C1CCCN1C(=O)NCC1(c2ccc(F)cc2F)CC1 +O=S(=O)(NCCc1c(F)cccc1F)c1cccc(F)c1 +CC(c1ccncc1)N(C)C(=O)NCc1nccn1Cc1ccccc1 +N#Cc1ccc(C(=O)NC(C(N)=O)c2ccc(F)cc2)cc1 +NS(=O)(=O)c1cccc(C(F)(F)F)c1Br +COc1ccc(NC(C)=O)cc1C(O)CCCCO +COC(=O)c1cccc(CCNC(=O)NCc2ccc(C)nc2)c1 +COc1ncccc1CNC(=O)c1ccn(-c2ccc(F)cc2)n1 +CCC1=C(NS(=O)(=O)c2ccc(C)cc2)CN(CC)C1=O +Cn1nccc1C(=O)Nc1nc2c(cc3c4c(cccc42)CC3)s1 +CC(CNC(=O)C1(c2ccccc2F)CC1)Oc1cccnc1 +O=C(Nc1nc2c(s1)CCCC2)C(c1ccccc1)n1cnnn1 +Cc1cc(C)n2nc(C(=O)Nc3ccccc3-n3cncn3)nc2n1 +O=C(c1ccncc1)c1ncc(-c2cccnc2)o1 +CN(C)c1oc(-c2ccccc2)nc1S(=O)(=O)c1ccccc1 +COc1ccccc1OC(=O)c1cccc2c1OCCO2 +Cc1nc2sccc2c(=O)n1NC(=O)COc1ccc(Cl)cc1 +Cc1cccc(N2CCN(CC(=O)NCc3cc(=O)[nH]cn3)CC2)c1 +CNc1ccc(NS(=O)(=O)c2ccccc2)cc1OC +COc1ccc(CNC(=O)NCC(O)c2ccc3c(c2)CCO3)cc1 +COC(=O)c1cccc2nc(-c3ccccc3)nn12 +Cc1cc(C)c(C(=O)N(C)Cc2ncnn2C)c(C)c1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(NC(C)C)nc1 +CCC(O)Cc1ccc(S(=O)(=O)N(C)C)cc1 +O=C(Cc1cccc(F)c1F)N(CCO)CCc1ccccc1 +O=S(=O)(NC1CCCC1)c1ccc(Cl)cc1F +COc1cc2cc(C(=O)N(C)c3ccccc3)[nH]c2c(OC)c1OC +COc1ccc2c(c1)C(c1cnc(C)cn1)NCC2 +CCOC(=O)c1ccn(-c2cccc(NC(=O)NC(C)(C)C)c2)n1 +CC(=O)Nc1cccc(NC(=O)COc2ccc3c(c2)CCC3)c1 +Cn1ncc(C(=O)NC2(c3cccc(Cl)c3)CC2)c1N +O=C(CSc1ncn[nH]1)N1CCOC(c2ccc(F)cc2)C1 +CC(NS(=O)(=O)c1ccc(Cl)cc1N)C(N)=O +COc1ccc(CNC(=O)Cn2cnc3onc(C)c3c2=O)cc1 +CCNC(=O)CN1CCN(S(=O)(=O)Cc2ccccc2)CC1 +COc1cc(C)c(C(O)C(N)=O)cc1C(C)(C)C +CCOC(=O)Cc1ccc(NC(=O)N(C)Cc2csc(C)n2)cc1 +Cc1ccc2c(c1F)CCNC2C(=O)c1cccs1 +CC(=O)C(C)Oc1cc2oc(=O)cc(C)c2cc1Cl +COC(=O)C1=C(C)C(C(=O)COC(=O)c2cnn(C)c2C)=NC1C +Nc1cccc(-c2nnc(-c3ccc4[nH]ccc4c3)o2)c1 +NC(=O)C(NC(=O)Cn1ccc2ccc(Cl)cc21)c1ccccc1 +COC(=O)CC(c1ccc(C(=O)OC)cc1)c1c(O)n[nH]c1C +COC(=O)C1CN(C(=O)c2cccs2)CCN1 +Cn1cnnc1-c1ccc(NC(=O)C2CCCCC2)cc1 +O=C(OCC1CCOCC1)c1ccc(-n2ccnc2)cc1 +Cc1cc(C(C)NC(=O)Cc2ccccc2Cl)c(C)o1 +Cc1cc(COc2ccc3ccc(=O)oc3c2)on1 +O=C(CCC(=O)c1cccs1)Nc1n[nH]c2cccc(F)c12 +COc1cc(CNC(=O)CCCc2ccc(Cl)cc2)ccc1O +CNS(=O)(=O)c1ccc(C)c(C(=O)NCCc2ccccn2)c1 +CCOC(=O)C1(Cc2ccc(F)cc2)CCCN(C(=O)CC)C1 +O=C(Nc1cccc(CN2CCCC2=O)c1)c1ccc2[nH]cnc2c1 +CC(=O)c1ccc(Oc2ccc(C(=O)Nc3ccnn3C)cc2)cc1 +Cn1cc(C(=O)NCC2CCCO2)c2ccccc21 +CCOc1cccc(CC(=O)Nc2noc3ccccc23)c1OCC +CC(NC(C)c1ccc2c(c1)OCO2)C(=O)NC(C)(C)C +Cc1cc(C)cc(NC(=O)c2cccc(-c3ncon3)c2)c1 +Cc1ccc(Cl)cc1NCc1nc(C)c(C)s1 +COC(C(=O)NC(C)C1(N2CCOCC2)CCCC1)c1ccccc1 +COc1ccc(C(O)C2CC(=O)N(C(C)C)C2)cc1OC +CCOc1ncccc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +COc1cc(C(=O)N2CC3CCC2CN(C(=O)N(C)C)C3)ccc1O +Cc1cnn(Cc2ncc(-c3ccc(Cl)cc3)o2)c1 +COCCSc1nnc(-c2cn(C)nc2OC)n1C +C#CCNC(=O)Cc1cc(OCC)c(OCC)cc1Br +O=C(c1cnccn1)N1CCC(Cc2cnc3[nH]ccc3c2)C1 +CCc1nc2n(n1)CCCC2NC(=O)C1CC(=O)N(CCOC)C1 +CSc1cccc(C(=O)Nc2nnc(-c3ccc(F)cc3)o2)c1 +c1ccc(Cn2ccnc2Cn2nccc2-c2ccncc2)cc1 +CCc1nc(CNc2ccc(C(=O)NC3CCCC3)cc2C)no1 +CCn1nc(C(=O)Nc2ccc(C(C)C)cc2)ccc1=O +c1ccc(CCNCc2ccc3nccnc3c2)cc1 +CC(=O)c1ccc(OC(=O)c2cccc(CN3CCCC3=O)c2)cc1 +CCCCN1C(=O)CC(C(=O)NCC)C1c1ccc(OC)cc1 +COC(=O)c1cc(OC)c(OC)cc1NC(=O)c1ccccc1 +CCn1nc(C)c(C(=O)NCCN2CCOCC2)c1C +CC(=O)c1cccc(NC(=O)COc2ccc(Br)cc2)c1 +Cc1cc(C)n2ncc(C(=O)NC(C)c3nc(CC(C)C)no3)c2n1 +CCNC(=O)CCC(=O)c1cc(C)c(OC)cc1C +Nc1c(-c2cc(F)ccc2F)nnn1-c1cccc(F)c1 +C#CCNC(=O)COc1cc2sc(C)nc2c2sccc12 +COCC(=O)Nc1cccc(NCC(=O)Nc2cccc(C#N)c2)c1 +CC(=O)NCCc1ccc(-c2cn3cc(Cl)ccc3n2)cc1 +CCC(C)C(=O)Nc1cc(F)c(OC)cc1OC +CCNc1ccc(S(=O)(=O)N2CCCC(O)C2)cn1 +CC(=O)Nc1nc(C(=O)NCCCCN2CCOCC2)cs1 +Cc1cc(-c2ccccc2)nc(N(C)C)c1S(C)(=O)=O +Cc1cc(C(C)NC(=O)NCc2cccs2)c(C)o1 +CCOC(=O)CC(C)Sc1nnnn1-c1ccccc1 +CCOc1ccccc1C(=O)N1CCC(CO)CC1 +CN1C(=O)CCC2C1CCN2Cc1cccs1 +CCCC1CN(C(=O)CCC2Cc3ccccc3NC2=O)CCO1 +CCN(CC)C(=O)c1ccc(NC(=O)c2ccccc2C)cc1 +CCOC(=O)CC1CCCCN1C(=O)Cc1cccc(OC)c1 +Cn1c(=O)n(-c2ccc(Cl)c(N)c2)c2ccccc21 +Cc1noc(C)c1CC(=O)N(C1CC1)C(C)c1ccccn1 +CC1CCCN(S(=O)(=O)N2CCN(C(=O)N(C)C)CC2)C1 +CCc1oc(C(=O)N2CCN(C(=O)CO)CC2)cc1C +Cc1ccc(CNC(=O)c2nc(N(C)C)c3c(C)scc3n2)o1 +COC(=O)Nc1cc(NC(=O)COc2ccccc2)ccc1F +COc1ccc(NC(=O)NCc2ccc(C(C)O)cc2)cc1 +COC(=O)C(CC(C)C)NC(=O)Cc1csc(C)n1 +CC(C)CNC(=O)COc1c[nH]c(CO)cc1=O +COCc1oc(-c2ccc(F)c(F)c2)cc1CC#N +O=C(CSc1cn[nH]n1)Nc1ccccc1F +CC(C)(C)c1csc(N(CCC#N)CCC#N)n1 +N#Cc1ccc(NC(=O)COCC2CCCO2)cc1Cl +O=C(c1cccc(-n2cnnn2)c1)N1CCCC1c1cccc(F)c1 +CCc1oc2ccccc2c1CN1CCOC(c2nc(C)cs2)C1 +Cc1cc(F)ccc1N1CCCC(NC(=O)C2CCC2)C1 +O=C(NCCc1n[nH]c(-c2ccc(F)cc2)n1)c1ccccc1F +O=S(=O)(c1cccnc1)N1CCCC(c2cc3cccnc3[nH]2)C1 +CN(C)c1nc(C2CCN(C(=O)C3CCOC3)C2)cc(=O)[nH]1 +O=C(CNS(=O)(=O)c1cccc(F)c1)NCCc1ccccc1 +COc1cccc(C(=O)NCC(C)Cn2cccn2)c1F +CC(C)Cn1cc(C(=O)OC(C)C)c2ccccc2c1=O +Cc1nc(CNC(=O)N2CCN(c3ccc(F)cc3)CC2)cs1 +Cc1ccccc1-n1ccc2c(cnc3ncnn32)c1=O +CC(=O)Nc1ccc(-c2nc(N3CCOCC3)sc2C)cc1 +CCc1nc(C)c(C(C)OC(=O)c2ccoc2)s1 +Cc1cc(NCC(=O)NC(C)(C#N)C2CC2)ccc1C(=O)N(C)C +CC(=O)Nc1cc(C(=O)N2CCOCC2)ccc1F +NS(=O)(=O)c1cc(C(=O)NC2CCCCC2)ccc1F +O=C(Nc1cccnc1)C1CCN(C(=O)c2cccs2)CC1 +CC1CNC(c2ccccc2)CN1C(=O)c1cccc(F)c1 +COc1ccc(-c2nc3cc(N)ccc3[nH]2)cc1Br +CCNC(=O)c1cccc(CNC(=O)C2COc3ccccc3C2)c1 +CCOc1ccc(Cc2c[nH]c(C)c2C(=O)OC)cc1 +COC(=O)c1cccnc1N1CCN(c2ccccc2Cl)CC1 +COC(=O)C1CCCN1Cc1c[nH]nc1-c1ccc(OC)c(F)c1 +CC(NC(=O)Cc1ccccn1)C12CC3CC(CC(O)(C3)C1)C2 +Cc1nc2ccccc2n1CCCNC(=O)Cn1ccc2ccccc21 +O=C(Cc1ccon1)NCc1ccn(-c2ccc(F)cc2)n1 +Cc1nccn1Cc1nnc(C(=O)NCc2ccc(F)cc2)s1 +Cc1nc(N(C)C)sc1CNc1cnn(CC(F)F)c1 +Cc1nn(Cc2ccc(C(=O)NCc3cccnc3)o2)c(C)c1Cl +CCOc1ccc(Cl)cc1C(=O)Nc1nccs1 +CC(C)Cn1c(SCC(N)=O)nnc1-c1ccco1 +Cc1cnn(CC2CN(Cc3cscn3)CCO2)c1 +CC(=O)Nc1ccc(SC(C)c2nc(N)nc(N(C)C)n2)cc1 +N#Cc1ccc(C(=O)N2Cc3ccccc3C(c3ccccc3)C2)cc1 +CCCCC(=O)Nc1cccc(C(=O)Nc2cc(C)ccn2)c1 +C=CCn1c(=O)sc2cc(NC(=O)C3CC3)ccc21 +NC(=O)c1c(NC(=O)CSc2ccc(O)cc2)sc2c1CCC2 +CCOc1cc(CN2CCOC(C)(C)C2)cc(Cl)c1OC +Cc1cc(CS(=O)(=O)NC(C)c2ccc3ccccc3c2)on1 +CCOC(=O)C1CCN(C(=O)c2cnns2)CC1 +COC(=O)CCNC(=O)c1cc2cn(C(C)C)cc2s1 +CCCCN(Cc1nc2ccccc2c(=O)[nH]1)C(C)C +CCCCNc1cccc(OC(=O)C2CCCO2)c1 +COCCNC(=O)c1cc2occ(-c3cccnc3)c2[nH]1 +O=S(=O)(c1cn[nH]c1)N1CCCc2ccccc21 +CC(NS(=O)(=O)c1cn[nH]c1)c1ccc(Br)cc1 +CC(CS(=O)(=O)c1ccccc1)N1CCN(c2ccco2)CC1 +CCC(NC(=O)c1cc(OC)cc(OC)c1)C(C)C +CCNc1nnc(-c2csc(N3CCOCC3)n2)s1 +Cc1nc2ccccn2c1C(=O)NCc1ccco1 +O=C(NC1CC1)N1CCC(C(O)c2ccccc2)CC1 +CCCOc1ccc(-c2cc(C(=O)OC)no2)cc1OC +O=C(C1=NC=NC1C(=O)Nc1ccccn1)c1ccccc1 +Cc1ccc(-c2nnco2)cc1NC(=O)c1ccc(-n2ccnn2)cc1 +Cn1c(C2C(=O)Cn3c2nc(=O)c2ccccc23)nc2ccccc21 +Cc1csc(CCNCc2ccc3c(c2)OCO3)n1 +CCC(C)n1ncc(C(=O)N2CCCC(n3cccn3)C2)c1C1CC1 +O=C(NCC(O)c1cccc(OC(F)F)c1)c1cccs1 +CC(C)OC(=O)c1cnn2c(C(F)(F)F)cc(-c3ccco3)nc12 +O=C(NCc1ccc(Cn2cncn2)cc1)C1Cc2ccccc2O1 +Cc1ccc(N)cc1NC(=O)c1ccc(Br)cc1 +COc1ccc(S(=O)(=O)N2CCCC3CN(C(C)=O)CC32)cc1 +Cc1ccc(Cl)cc1S(=O)(=O)N(C)Cc1ccoc1C +COC(=O)CN(C)C(=O)c1ccc(C(F)(F)F)nc1C +CCOC(=O)c1cc(N)n(CCCc2ccccc2)n1 +Cc1ccccc1C1(CNC(=O)c2scnc2C2CC2)CC1 +Cc1cc(C)nc(C(C#N)C(=O)c2csc(-c3ccc(C)o3)n2)n1 +N#Cc1ccc(NC2CCN(C3CC3)C2=O)cc1C(F)(F)F +O=C1NCCCn2cc(S(=O)(=O)NCc3ccccc3F)cc21 +Cc1c(CCCO)nnn1-c1nc2c(s1)CCCC2 +Cc1cn2nc(N(C)C3CCN(c4ccccc4)C3=O)sc2n1 +COc1ccc(Cl)cc1NC(=O)NCc1cnn2ccccc12 +Cc1ncc2c(n1)CCCC2NC(=O)c1cccc(C#N)c1 +Cc1cc(C)cc(N2CCC(C(=O)N3CCN(C(C)C)CC3)C2=O)c1 +Cc1cc(C(=O)NCCCn2cncn2)sc1C +O=C(NC1CCN(C(=O)C2CC=CC2)CC1)c1ccccc1F +Cc1ccccc1NC(=O)C(C)S(=O)(=O)c1nncn1C(C)C +CC(CC(=O)N1CCN(CC(N)=O)CC1)C1CCCCC1 +Nc1ccnc(C(=O)Nc2ccccc2Oc2ccccc2)c1 +COC(=O)NCCCC(=O)N(C)Cc1c(C)nc2sc(C)cn12 +Fc1ccc(-c2n[nH]cc2CNCc2ccccc2-n2ccnc2)cc1 +COc1ccc(-c2c(-c3ccc(F)cc3)noc2N)cc1OC +Cc1nccn1-c1ccc(CNC(=O)c2ccc3[nH]cnc3c2)cc1F +FC(F)Oc1ccc(-n2cc(Br)cn2)cc1 +Cc1cc2[nH]c(=O)[nH]c2cc1S(=O)(=O)NCCc1ccccc1 +CC(C)NC(=O)c1ccc(NCC(=O)N2C(C)CCCC2C)cc1 +O=C(CNc1cccc(F)c1)Nc1ccc(Cl)cn1 +COc1ccc(OCCOc2ccc(-n3cnnn3)cc2)cc1 +CC1CCCC(CNC(=O)C(C)NC(=O)c2cccs2)C1 +Cc1ccccc1CC(C)NC(=O)c1nonc1N +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)cc1 +CCCN(C)S(=O)(=O)c1cccc(Cl)c1C#N +NC(=O)c1ccc(CNc2ccc(Br)cc2)cc1 +COc1ccc(-c2ccc3c(=O)[nH]cnc3c2)cc1Cl +COc1ccccc1OC(C)C(=O)Nc1cccc(N)c1 +COC(=O)c1cc(C)sc1NC(=O)c1ccc2c(c1)OCCO2 +CCC1CCCN(c2ccc(F)cc2C(C)O)C1 +O=C(Nn1cnc2ccccc21)c1cccc(Br)c1 +CC(Sc1nc2cc3ccccc3cc2c(=O)n1C)C(=O)N(C)C +NC(=O)c1ccc(NC(=O)c2cc3cc(Cl)ccc3o2)cc1Cl +O=C(NCc1cccc(Br)c1)C1CCCO1 +Cc1nc(CN2C(=O)COC3CN(c4ncccn4)CC32)cs1 +OC(COc1ccc2ccccc2c1Cl)Cn1ccnc1 +CCC(C)(NC(=O)CCNC(=O)c1cccs1)C(F)(F)F +CCN(CCO)C(=O)c1ccccc1-n1cccn1 +O=C(c1ccc(F)cc1F)N1CCc2nc3cccnc3cc2C1 +O=C(Nc1cn[nH]c1)c1ccc(=O)n(Cc2ccccc2)n1 +CC(CNC(=O)c1cc2c(s1)CCCC2)c1nccs1 +CC(=O)Nc1cc(NC(=O)N(C)CC2CCCC2)c(F)cc1F +CC(CNC(=O)Cn1c(=O)n(C)c2ccccc21)N1CCOCC1 +CC(O)(CNC(=O)Nc1ccc(F)cc1Cl)c1ccsc1 +CC(C)Oc1ncccc1CNC(=O)NCC1CCC1 +CN(CCN1CCOCC1)C(=O)COc1ccc(F)cc1F +Cc1nnc2n1CC(NC(=O)C1(C#N)CCCC1)CC2 +CCC(C)CN(C)C(=O)c1cccnc1OCC(F)F +O=C(NCCNC1=NS(=O)(=O)c2ccccc21)c1ccccc1F +COc1cccc(CNC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)c1 +Cc1nnnn1-c1ccc(F)c(NC(=O)CCOCC2CCCO2)c1 +CN(Cc1nnc(C2CC2)n1C)C(=O)Cc1cccc(OCC#N)c1 +CCn1c(NC(=O)c2cnn(Cc3ccccc3)c2)nc2ccccc21 +Cc1ccc(NC(=O)c2ncn(-c3ccccc3)n2)cc1 +COc1ccc(C2CC(c3ccc(C)cc3)=Nc3nnnn32)c(OC)c1 +COc1cc(C(=O)NCc2ccc3c(c2)OCO3)nc2ccccc12 +CCCC1CCCN(C(=O)c2ccc(OCC(N)=O)c(OC)c2)CC1 +CC(=O)NCc1ccc(C(=O)N(CC(C)C)C2CCCCC2)s1 +Cc1ccn2ncc(C(=O)N(Cc3ccc(F)cc3)CC3CC3)c2n1 +CC(C)(C)c1ccc(C(=O)NCc2cccnc2)c(N)n1 +COc1ccccc1NC(C)C(=O)Nc1ccc2c(c1)OCCCO2 +CC(c1ccccn1)N(C)C(=O)CCC(=O)Nc1nccs1 +CC(C)(C(=O)Nc1ccc(C(N)=O)cc1)c1ccc(F)cc1 +Cc1cc(NC(=O)CCc2ccc(Cl)cc2)ccc1C(=O)N(C)C +Cc1ccnc(NC(=O)c2cc(-c3ccccc3)nc3c2cnn3C)c1 +COc1ccc(C(=O)Nc2c[nH]cc(Br)c2=O)c(C)c1 +Cc1c(C(C)NC(=O)C2(C)Sc3ccccc3NC2=O)cnn1C +O=C(COc1cc(Cl)ccc1Cl)N(CCO)C1CC1 +Cn1nc(C2CC2)nc1-c1cc(-c2ccccc2F)n[nH]1 +CCn1c(-c2ccccc2C)nnc1S(=O)(=O)Cc1noc(C)n1 +Cc1nn(C)c2nc(-c3ccccn3)nc(NC(C)c3ccco3)c12 +CNC(=O)c1cccc(NC(=O)c2cccc(C)n2)c1 +O=C(N=c1ccccn1Cc1ccccc1)c1ccc2nccn2c1 +CSc1ccc(NC(=O)NCC2COc3ccccc3O2)cc1 +CC(C)n1nccc1NC(=O)CSc1nc2ccccc2s1 +CCOc1cc(C(=O)N2C(C)COCC2C)ccc1OC +CCC(C)n1c(-c2ccc(C)cc2)ccc(N)c1=O +CCNC(=O)Cn1c(CO)cnc1SCc1cc(C)ccc1C +Cc1ccc(-n2cnnc2SCc2c(C)noc2C)c(C)c1 +COc1ccc(C(=O)Nc2ccc(NC(=O)C(C)C)c(OC)c2)cc1 +CC(NS(=O)(=O)c1cccc(C(=O)N(C)C)c1)c1ccccc1 +COC(=O)c1ccc(-c2cc(F)ccc2OC)o1 +O=C(Nc1ccc(-n2cncn2)cc1)c1cc(OCC(F)F)ccn1 +CCOC(=O)c1c(C)nn(-c2cccc(F)c2)c1C(F)(F)F +OCCn1ccnc1-c1cc(Cl)cc(Cl)c1 +c1ccc(-c2noc3c2CN(c2ncccn2)CC3)cc1 +CC(Nc1cnc2ccccc2n1)c1ccc(S(C)(=O)=O)c(F)c1 +Cc1nn(C)c(C)c1OS(=O)(=O)c1cnn(C2CCOCC2)c1 +CC(=O)c1ccc(C(=O)NCc2nncn2C2CC2)cc1 +Nc1ccc2oc(CC(=O)NCc3ccc(F)cc3)nc2c1 +CCOCC(=O)Nc1nc(-c2c[nH]c(C(N)=O)c2)cs1 +CC(CC(=O)NC1CC1)CC1=NS(=O)(=O)c2ccccc2N1 +Cc1nc(NCc2csc(C)n2)c2c3c(sc2n1)CCC3 +O=C(c1ccc(=O)[nH]c1)N1CCC(CCn2cccn2)CC1 +Cc1ccccc1-c1nc(C#N)c(N2CCC(C(N)=O)CC2)o1 +CC(=O)N1CCN(C(=O)Nc2ccc(S(N)(=O)=O)cc2)CC1 +Cc1c(N)cccc1NC(=O)CCOC1CCCCC1C +CCS(=O)(=O)c1ccc(-c2cc(N)no2)cc1 +CC(C)n1c(=O)c2sccc2n(Cc2ccccc2F)c1=O +CCCOC(=O)c1ccc(NC(=O)C2CCOC2)cc1 +Nc1cccc(N2CCN(C(=O)C3CCC3)CC2)c1 +COc1cccc(C2CCCN2C(=O)c2nc3nccc(C)n3n2)c1 +COC(=O)c1c(C(=O)OC)c(-c2ccc(Cl)cc2)n2c1CCC2 +CC(=O)Nc1nc(CC(=O)NCc2cccs2)cs1 +O=C(Nc1ccc(NC(=O)C2CC2)cc1)c1cncn1-c1ccccc1 +COc1ccc(NC(=O)c2cc(Cl)c3c(c2)OCCO3)cn1 +Cc1ccccc1-c1nc(C)c(CNC(=O)c2ccco2)s1 +Cn1ncc2c(NCCNC(=O)C3CC3c3ccccc3)ncnc21 +CC(=O)c1cc(C(=O)N2CCN(c3nccs3)CC2)n(C)c1 +COC(=O)c1cccc(NC(=O)CCC2C(=O)N=C(C)N=C2C)c1 +CCS(=O)(=O)N(C)C1C2CC3CC(C2)CC1C3 +O=C(Cc1cccc(F)c1)N1CCC2OC(COCC3CC3)CCC21 +Cc1cc(C)n2nc(SCc3ccccc3)nc2n1 +CC(=O)N1CCc2cc(C(O)CN(C)Cc3ccccc3)ccc21 +NC(c1ccccc1)c1nc2cccnc2n1CCO +COc1ccc(C)nc1NC(=O)NCc1c(C)nn(C)c1C +COc1ccc(NC(=O)Nc2ccc(N)cc2Cl)cc1 +COC(=O)c1cc(Cl)ccc1NCc1cncs1 +CCC(Sc1nc2ncccc2[nH]1)C(=O)NC1CCCC1 +Cc1ccc(-c2nn(-c3ccccc3)cc2NC(N)=O)cc1 +Nc1cc2c(cc1-n1cc(Br)cn1)NC(=O)CO2 +COc1ccc(C(=O)CNc2ccc(C)cc2)cc1N +O=C(NC1CCCCC1)C1CC(=O)N(c2n[nH]c3ccccc23)C1 +CC(C)CCC(=O)N1CCCc2cc(S(C)(=O)=O)ccc21 +CC(Cn1cccn1)C(=O)N1CCC(c2cc3nccnc3[nH]2)CC1 +Cc1nn(C)c(N)c1Cn1c(C)c(C)sc1=O +CCc1ncc(C(=O)NCc2ccc(OC(C)C)cc2)c(C)n1 +CCCCN(C)C(=O)c1cc(N)n(-c2ccc(C)c(C)c2)n1 +CCOC(=O)C1N=C(c2ccc(C(C)(C)C)cc2)OC1=O +COc1cccc(OC)c1OCc1cc(C)n(C)n1 +COc1ccc(CCC(=O)Nc2cccc(C(N)=O)c2)cc1 +CCOc1ccc(F)c(C(=O)NCCc2csc(CC)n2)c1F +CN1CCOC(CNC(=O)Cc2ccccc2F)C1 +COC(=O)c1ccc(F)c(NC(=O)COCC(F)(F)F)c1 +Cc1cccc(NC(=O)COC(=O)Cn2cnc3ccccc32)c1C +O=C(Nc1cccc(C(F)(F)F)c1)c1cc(-c2ccco2)on1 +COc1cc(OC)cc(C(=O)Nc2cc(C(C)=O)ccc2OC)c1 +O=C(NCCO)NCc1ccc(COc2ccccc2)cc1 +Cc1nc(CNC(=O)C(C)Oc2ccccc2F)no1 +CNC(=O)Nc1ccc(NC(=O)c2ccccc2F)cc1 +CC(C)NC(=O)COC(=O)c1ccccc1C(=O)c1ccccc1 +CC1Oc2cc(N)ccc2N(Cc2ccccc2Cl)C1=O +CN(CC1CC1)C(=O)NC1CCCc2c1cnn2Cc1ccccc1 +CC1(CNC(=O)NCc2ccnc(OC(C)(C)C)c2)CCC1 +CCN(CC)C(=O)c1ccc(-c2ccc(F)cc2F)nc1N +COCc1nc2nc(C)nn2c(N)c1-c1ccc(OC)cc1 +COc1ccc(C(=O)C(C)Sc2nnc(C)o2)cc1 +COc1cccc(-n2ccnc2SCCCc2cnn(C)c2)c1 +Cc1sc2nc(-c3cccnc3)nc(N3CCC3)c2c1C +CC(NC(=O)c1noc(-c2ccc(F)cc2)n1)c1ccc(F)cc1 +CCOc1ccc(CN(C)S(=O)(=O)c2ccc(F)c(F)c2)cc1 +COc1ccccc1NC(=O)c1cnc2ccc(C)cn2c1=O +Cc1noc(C(C)OC(=O)c2ccccc2Oc2cccnc2)n1 +COc1cccc(-c2nnc(-c3ccc(-n4ccnc4)nc3)o2)c1 +Cc1nnnn1-c1ccccc1C(=O)NC(C)CCc1ccccc1 +CC(C)N1CC(C(=O)Nc2cccc(C#Cc3ccccn3)c2)CC1=O +COCCn1cnc2nnc3ccc(C(=O)NC4CCCC4)cc3c21 +OCc1csc(CCOc2ccccc2F)n1 +CC(=O)N1CCCC1C(=O)NC(C)c1ccccc1Cl +N#Cc1ccc(-c2ccccc2)nc1N1CCOCC1 +CC(c1cccc(Cl)c1)N(C)C(=O)c1ccc(S(N)(=O)=O)o1 +Cc1cc(-c2nc3sc(C4CCC4)nn3c2C#N)ccc1F +COc1ncccc1NC(=O)c1cn(-c2ccc(F)cc2)nn1 +O=C(NCc1nc(-c2ccccc2)no1)c1cccnc1 +O=C(NCCc1ccc(O)cc1)Nc1ccc2c(c1)OCCO2 +Cc1cccc(OCC(=O)NCCOc2ccccc2)c1 +Cc1cnc(CNC(=O)CCc2c(C)noc2C)cn1 +COc1ccc(C(=O)Nc2cccc(CO)n2)cc1 +N#Cc1cc(NC(=O)COCCc2ccccc2)ccc1F +CCCN(CC(=O)Nc1ccc(Cl)cc1)C(=O)c1ccncc1F +COc1ccccc1NC(=O)NCCc1n[nH]c(-c2ccco2)n1 +O=C(CNC(=O)c1ccc(N2CCCOC2=O)cc1)NC1CC1 +Fc1cc(F)c2c(c1)C(c1ccc3nc[nH]c3c1)NCC2 +Cc1cn2nc(Sc3nc(Cc4cccs4)n[nH]3)sc2n1 +Cc1cccc(CC(=O)Nc2ccc(S(=O)(=O)NC(C)C)cc2)c1 +COc1cc(NC(=O)Cc2c(C)noc2C)cc(OC)c1OC +CC(C)C(C)N(CC(F)(F)F)C(=O)C1Cc2ccccc2C(=O)O1 +CC(C)C(=O)Nc1cccc(NC(=O)c2ccc(O)c(Cl)c2)c1 +O=C(CC1NC(=O)c2ccccc21)Nc1ccc(F)c(Cl)c1 +C#Cc1cc(F)c(NC(=O)C(C)OCC2CCCO2)c(F)c1 +CCC1CN(C(=O)NCc2nccn2Cc2ccccc2)CC(C)O1 +N#CCCN(CCC#N)C(=O)Cn1cc(Br)ccc1=O +O=C(NCCN1CCc2ccccc21)C1CC=CCC1 +CC(C)Oc1ccc(NC(=O)COc2cccc(N)c2)cc1 +Cc1ccc(F)c2c1CCNC2c1c[nH]c(=O)c(Cl)c1 +Cc1cc(C)c(C(=O)Nc2cccc(C(=O)NC(C)(C)C)c2)c(=O)[nH]1 +Cc1cccc(C2N(c3nccs3)C(=O)C3CCCN32)c1 +CCCOc1ccc(NC(=O)NCc2ncoc2C)cc1Cl +COc1ccc(OC)c(C(O)CNc2nccn3cnnc23)c1 +Cc1cccc(C)c1NC(=O)COc1c(C)cccc1C +CCn1c2ccccc2c2cc(NC(=O)c3ccc(=O)n(C)c3)ccc21 +CCSc1ccccc1NC(=O)N(Cc1ccccn1)C(C)C +CC(C)(C)N1CC(C(=O)N2CCN(CCn3cncn3)CC2)CC1=O 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+CCCN(CC(=O)OC)C(=O)c1c(F)cccc1Cl +CC(COc1ccc(F)cc1F)NC(=O)NCCN1CCOCC1 +COc1ccc(C(=O)CCC(=O)NCc2ncc[nH]2)cc1F +N#CCCCCS(=O)(=O)N1CCN(c2ccc(Cl)cn2)CC1 +O=C1CCC(COC(=O)Cn2cc(Br)ccc2=O)N1 +NC(=O)c1ccc(NS(=O)(=O)c2ccccc2C(F)(F)F)cc1 +O=C(NCC1CCCO1)c1cc2c([nH]c1=O)CCC2 +CC1CN(Cc2nc(C3CC3)no2)CCN1Cc1nc(C2CC2)no1 +COc1cccc(C(=O)NCC(c2ccccc2)N2CCOCC2)c1 +COc1cc(CNC(=O)C2CCN(C(=O)C3CC3)CC2)ccn1 +O=C(CSc1ncccn1)Nc1ccc2c(c1)OCO2 +CCOC1C(OCC)N(S(C)(=O)=O)CCN1S(C)(=O)=O +Cc1nc(C)c(COc2cccc(Oc3ncccn3)c2)s1 +CNC(=O)NCC(=O)N1CCC(Cc2ccccc2)C1 +CCC(=O)Nc1cccc(C(=O)Nc2c(C)cccc2CC)c1 +CCOc1ccccc1-c1nnn(-c2ccccc2)c1N +Cc1csc(S(=O)(=O)C(C)C(=O)Nc2cc(F)ccc2F)n1 +CCn1nc(C)c2nnn(CC(=O)N3CCCCC3)c(=O)c21 +COC(=O)c1ccc(C(N)C(=O)NCCCO)cc1 +Cc1ccc(NC(=O)CSc2ccc(-c3ccncc3)nn2)cc1 +Cc1ccc(NC(=O)Nc2ccccc2SCCC#N)cc1 +O=C(CCC(O)c1cccs1)Nc1ccccc1Cl +CN(Cc1cccnc1)C(=O)CN(C)S(C)(=O)=O +CC(C)CC(C)(C#N)NC(=O)c1ccc(=O)n(-c2ccc(F)cc2)n1 +COc1ccc(CNC(=O)c2ccc(C)cc2C)c(OC)c1OC +COCc1cccc(NC(=O)C2(C)CC2(Cl)Cl)c1 +Cc1cc(NC(=O)CNc2ccccc2C(N)=O)on1 +Cn1ccnc1C(Nc1ncnc2ccsc12)c1cccc(F)c1 +O=C(Nc1cccc(N2CCCC2=O)c1)NC(CO)c1ccccc1 +O=C(Nc1ccccc1S(=O)(=O)N1CCCC1)c1ccoc1 +C#CCNC(=O)CSc1nnc(-c2ccc(OC)cc2)n1N +Cc1nc(NC(=O)CCOC(C)CC(C)C)n[nH]1 +CC(=O)c1ccc(C(=O)NC2c3ccccc3CC2O)cc1 +CCN1CC2(CCC1=O)CCN(C(=O)CCCn1cncn1)CC2 +CC(C)(C)c1ncc(Br)c(C2CC2)n1 +O=C(NCc1cc2ccccc2o1)c1cnccn1 +COc1ccc(N(C)S(=O)(=O)c2cnc3onc(C)c3c2)cn1 +CC1CCCC(C)N1C(=O)c1ccc(O)c(Cl)c1 +O=C(NCc1cccnc1)Nc1cccc(N2CCCCC2)c1 +O=C(c1ccccc1F)N1CC=C(c2c[nH]c3ccccc23)CC1 +COCC(=O)N1CCCC1c1cccc(Cc2ccccc2)n1 +CCNC(=O)CCC(=O)c1ccc(OC)c(N)c1 +CCOc1ccc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1OCC +O=S(=O)(CCc1ccccc1)c1ccc(F)c(F)c1 +CCC(OC)C(=O)NC1(c2noc(C)n2)CCCCC1 +O=C(CCNC(=O)C1CCCC1)Nc1c[nH]ccc1=O +Oc1c(F)ccc2c1CCNC2c1ccc(F)cc1 +COc1ccccc1Oc1ncccc1CNC(=O)c1ccc(C)nc1 +Cc1ccsc1CN(C)Cc1nc(C(C)C)no1 +CCS(=O)(=O)c1cccc(NC(=O)Cc2ccc[nH]2)c1 +COc1cc(CC(=O)N2CCCC2)ccc1OCc1ccccc1 +CC(C)CCn1ccc(NC(=O)N2CCCC2C(C)(C)O)n1 +COc1ccc(NC(=O)CC2OCCN(CCO)C2=O)cc1 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+Cn1cc(CCNC(=O)NCC2(c3ccccc3)CC2)cn1 +CC(C)C(=O)OCc1nc2ccccc2c(=O)n1Cc1ccco1 +CCN(CC)c1ncnc2sc3c(c12)CCCC3 +c1cncc(CCNc2nc3nonc3nc2NC2CCCC2)c1 +CCN(CC(C)C#N)C(=O)c1ccnc(-n2ccnc2)c1 +CN(Cc1nccn1C(F)F)C(=O)c1ccco1 +N#Cc1ccc(CN2CCN(c3ccc(O)cc3)CC2)cc1 +O=C(CCC1CCCO1)N1CCCc2cccc(OC(F)F)c21 +CC(=O)N1CCc2[nH]nc(-c3ccc(F)cc3)c2C1 +Cc1n[nH]c(C)c1CCC(=O)NCC(C(C)C)N1CCOCC1 +CC(C)OCCC(=O)N1CCC(NC(=O)c2cccnc2)CC1 +CCc1nc2nccc(-c3ccc(Br)cc3)n2n1 +Cc1c(C(=O)Nc2n[nH]c(-c3ccccn3)n2)oc2c1C(=O)CCC2 +COC1CCN(C(=O)c2ccco2)CC1Cc1cccc(C)c1 +CC(C)NC(=O)c1ccc(Cl)cc1NCC(=O)N(C)C +Cc1cccc(S(=O)(=O)CC(=O)Nc2c(C)cccc2C)c1 +CC(=O)Nc1ccc(NC(=O)N2CCOC(C)(C)C2)cc1 +Cc1ccc(CNC(=O)CC(C#N)c2cccnc2)cc1 +Cc1ccncc1NC(=O)NCC1(O)CCCCC1 +Cn1cnc(CNC(=O)CCNC(=O)c2n[nH]c3ccccc23)n1 +C=CCNc1nnc(SCc2cccc3cccnc23)s1 +O=c1c(S(=O)(=O)N2CCCC2)cccn1Cc1ccccc1 +O=C(c1ccc(=O)[nH]c1)N1CCN(C2CCCC2)CC1 +O=C(NCc1ccccn1)Nc1ccccc1N1CCCC1=O +CN(Cc1ccc(Br)cc1)C(=O)c1csnn1 +CCCOc1ccc(-c2ccc(C#N)c(=O)[nH]2)cc1 +CC(=O)NCC1CCN(S(=O)(=O)N2CCCCC2)CC1 +CCN(CC)C(=O)CCC(=O)OCC#Cc1ccccc1 +O=C1OCCC1Sc1nnc(-c2ccccc2)n1Cc1ccco1 +NS(=O)(=O)c1cncc(OC2CC2)c1C(F)(F)F +COC(=O)c1cc(-c2cccc(OC(F)F)c2)nc2onc(C)c12 +OC1CCC=C1c1cc(C2=CCCC2O)cc(C2=CCCC2O)c1 +CNc1nc(-c2ccc3c(c2)CCC(=O)N3C)cs1 +CS(=O)(=O)c1ccccc1NC1CCN(c2ncccc2F)C1 +COc1ccc(CN(C)CC(F)F)c(Cl)c1OC +CCc1nnc(SCC(=O)Nc2ccccc2O)n1CC(C)C +Cc1cnc(CCNC(=O)c2cc3ccccc3[nH]2)s1 +COCCN1CCN(CCOc2c(C)cccc2C)CC1=O +CCn1nc(C)c(NC(=O)NCCC(=O)N2CCCCCC2)c1C +CC1CC1c1ccc(CN(c2ccc(C#N)cn2)C2CC2)o1 +CN1C(=O)CC(COC(=O)c2ccco2)C1c1cccc(Cl)c1 +COc1cc(OC)c2cc(C#N)nc(-c3ccncc3)c2c1 +O=C(C1CC=CCC1)N1CCN(Cc2ccc3c(c2)OCCO3)CC1 +CC1(C)CC(=O)c2cnc(N3CCC(C(N)=O)CC3)nc2C1 +CN(C(=O)c1ccc2c(c1)nnn2C)c1ccc(-c2ccccc2)nn1 +Cc1cccc(Oc2ncccc2NC(=O)N(C)CCC(C)O)c1C +COC(=O)Cn1c(CCc2ccccc2)nc2ccccc21 +Cc1cc(=O)n(CCOc2cccc(Br)c2)cn1 +COc1cccc(-c2cc(-c3cccnc3)nn2CCNC(C)=O)c1 +COc1ccc(C(C)=O)c(OCC(=O)NCc2cccc(Cl)c2)c1 +COc1ccc(Cl)cc1CC(=O)Nc1nc(C(C)=O)cs1 +Cc1ccc(C(=O)Nn2cnc3sc4c(c3c2=O)CCCC4)s1 +CCC(=O)N1CCc2cc(C(=O)OCCOC(C)C)ccc21 +CC(NC(=O)c1c2c(nc3ccccc13)CCC2)C(=O)NC(C)(C)C +CN1CCN(C(=O)C2CC(=O)c3cc(F)ccc3C2)CC1 +Cc1noc(C)c1COC(=O)c1ccccc1-n1cnnn1 +Cc1c(Cl)cccc1NC(=O)c1cc(C(N)=O)cs1 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)Nc1nccs1 +COc1ccc(OC)c(CN(C)C(=O)Cn2ccc3ccccc32)c1 +O=C1COc2cc(C(=O)NCc3cnn(-c4ccccc4)c3)ccc2N1 +Cc1cc(CN2CCN(C(=O)NCCOc3ccccc3)CC2)on1 +O=C(CCn1cc(Cl)cn1)Nc1ccc2c(c1)OCCO2 +CCOc1ccccc1NC(=O)CN1C(=O)CSc2ccccc21 +Cc1ccc(C(=O)OCC(=O)c2ccc(Cl)cc2)o1 +Cc1ccsc1CN1CCC2(CC(OCc3cccnc3)CO2)C1 +COC(=O)CCNC(=O)Cc1c(F)cccc1Cl +Cn1c(NCC2COc3ccccc3O2)c(C#N)c(=O)n(C)c1=O +CCN(CC)C(=O)c1cccc(OCC(F)F)n1 +CCCc1nc(CSc2nc(C)nc(C)c2C(C)=O)no1 +O=C(CNC(=O)c1ccccc1OCc1ccc(F)cc1)NC1CC1 +O=C(NCc1cccnc1Oc1ccccc1)c1ccncc1 +CC(CC(N)=O)NC(=O)COc1ccccc1F +CC(C)(CNC(=O)CCc1ccccc1Cl)N1CCOCC1 +CC12CCC(C(=O)Oc3cccc4ccccc34)(OC1=O)C2(C)C +COC(=O)c1cc(Br)cnc1N1CCOCC1 +CCc1cc(C(O)C(C)(C)C)cc2c1NC(=O)C2C +Cc1nc(NC(=O)c2ccc3[nH]c(C(F)(F)F)nc3c2)sc1C +COc1ccccc1NC(=O)C(C)n1nnc(C(N)=O)c1C +COC(CNC(=O)c1snnc1C)c1ccsc1 +COc1ncccc1CNC(=O)NCCc1c(F)cccc1F +CCC(C(=O)Nc1cc(C2CC2)nc(C)n1)N1CCCC1=O +COC(=O)C1CCN(C(=O)c2c(C)nn3c(C)cc(C)nc23)CC1 +CN(CCC#N)C(=O)C1(C)Cc2ccccc2C(=O)O1 +CC(OC1CCCCCC1)c1nc(CNC(=O)c2ccccc2)no1 +O=C(Nc1cccc2cccnc12)c1cnc2cc[nH]c2c1 +COCCNC(=O)Cn1cc(-c2ccc(F)cc2)oc1=O +COC(=O)c1cc(N2CCCC(COc3ccc(C)cc3)C2)ncn1 +O=C(CCc1ccccc1)Nc1ccc(N2CCCC2=O)cc1 +CCOc1ccc(C(=O)NCC(c2c(F)cccc2F)N(C)C)cc1 +CCOc1ccc(CCC(=O)NCC(C)O)cc1N +Cc1oc2nc[nH]c(=O)c2c1C(=O)Nc1nc2c(s1)CCCCC2 +CCSc1ccc(C(=O)N2CCOCC2CC(C)C)cn1 +CC(=O)N1CCCc2cc(S(=O)(=O)N=c3cc(C)cc[nH]3)ccc21 +COCCC1(O)CCN(C(=O)c2cc3c(s2)CCCC3)CC1C +FC(F)(F)CNC(c1ccccc1)c1ccco1 +CN(C)c1ncc(-c2ccccc2Cl)cc1C#N +COc1ccc2c(c1)C(=O)CC(c1ccccc1)O2 +Nc1ccnc(Cn2ccc3ccn(Cc4ccccc4F)c3c2=O)n1 +CC1(C)C(NC(=O)COCc2ccccc2Cl)C2CCOC21 +CN(Cc1cnn(C)c1)c1cc(C(N)=O)c2ccccc2n1 +CCc1onc(C)c1NC(=O)c1cc(C)n(Cc2cccs2)c1C +Brc1cccc2sc(N3CCOCC3)nc12 +CCc1nnc(NC2CCN(C(=O)N3CCOCC3)CC2)o1 +CCn1c(SC(C)C(=O)N(C)CCC#N)nnc1C1CC1 +Cc1ccc(Cn2nccc2NC(=O)COCC(F)(F)F)o1 +Cc1nc(Cn2cnc3sc4c(c3c2=O)CCCCC4)no1 +C=CCN1CCC2(CCCN(C(=O)c3cnn(C)c3)C2)C1=O +Cc1ccnn1CCC(=O)N1CCCC(Nc2ccc(F)c(F)c2)C1 +CCNC(=O)c1cccc(S(=O)(=O)N2CCCCC2C)c1 +O=c1ccc(-c2csc(S(=O)(=O)N3CCOCC3)c2)n[nH]1 +CCCCN(CC)c1ncc(N)cc1Br +CN(Cc1ccc(F)cc1)C(=O)c1cccnc1OCC(F)F +COc1ccccc1CN1CCN(C(=O)Nc2ccccc2C)CC1 +Cc1ncc(CNC(=O)C2COc3ccc(F)cc3C2)s1 +CC(C)C(C)NC(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +NC1=Nc2nc3ccccc3n2C(c2c[nH]nc2-c2cccc(O)c2)N1 +Fc1cccc(F)c1CNCCc1ccsc1 +CCN(C(=O)NCc1ccc(S(N)(=O)=O)cc1)C1CCCCC1 +COc1cc(C)ccc1OS(=O)(=O)c1ccc(F)c(F)c1F +Cc1nc(CSc2ncccc2Cl)oc1C +CC(NC(=O)NC(C)c1cccs1)c1noc(-c2ccccc2)n1 +CN(Cc1ccccn1)C(=O)Nc1ccc(C(=O)NC2CC2)cc1 +Cc1ccncc1NC(=O)NCc1cccc(OCC(=O)N(C)C)c1 +O=C(Nc1nccs1)N1CC2CC3CC(C2)CC1C3 +O=C1NCCN1c1cccc(NCc2cccc3cn[nH]c23)c1 +CNC(=O)NCC(=O)N1CCC2(CCCC2)CC1 +Cc1cccc(=O)n1CCCCNC(=O)c1ccc(F)nc1 +COc1ccccc1CCNC(=O)c1ccc2oc(N(C)C)nc2c1 +Cc1occc1-c1nnc2sc(COc3ccc(F)cc3)nn12 +COc1ccccc1-c1nnc(SCC(=O)Nc2nccs2)o1 +CC(=O)c1csc(C(=O)NCc2nc3cccc(C)c3n2C)c1 +CN(CC1CCOCC1)S(=O)(=O)c1ccc(C(F)(F)F)nc1 +CC1CCCCC1Nc1cccc(NS(N)(=O)=O)c1 +O=S(=O)(Cc1nnnn1-c1ccccc1)c1ccc(O)cc1 +COCCc1ccc(OCc2ccc(C(N)=O)cc2)cc1 +CC(NC(=O)c1c[nH]nc1-c1ccccc1F)C(=O)N1CCOCC1 +Cc1cc(CN(C)C(=O)Nc2ccc3c(c2)CCC3)no1 +Cc1ccc(-n2ncc(C(=O)N3CCCCCC3)c2C)cc1 +CCn1cccc1C(=O)N(CC(=O)OC)C(C)C +COc1ccc(NC(=O)N2CCCCCC2)cc1N1CCCC1=O +CCCn1nnnc1CNc1ccccc1C(C)C +COC(=O)c1cc(OC(C)=O)c2cc(C)ccc2c1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)CSc1ccc(O)cc1 +C=CCn1c(C)nnc1SC(C)c1ccc(F)cc1 +CC(C)c1noc(CCC(=O)NCC2(C(N)=O)CCOCC2)n1 +COc1cccc(COC(=O)COc2ccccc2)c1 +CC1CCCCC1NC(=O)N(C)CC1CCCO1 +CC(NC(=O)CCNc1ncccn1)c1cccs1 +CCCOc1ccc(S(=O)(=O)N2CCN(CCO)CC2)cc1C +CC(=O)c1c[nH]c(C(=O)OC(C)C(=O)c2cc(C)c(C)cc2C)c1 +CC(Oc1ccc2cc(Br)ccc2c1)C(N)=O +CC(C)(C)c1ccccc1NC(=O)c1cnc(C2CC2)nc1N +N#Cc1ccc(Cc2cnc(NC(=O)Cn3cnnn3)s2)cc1 +CC(=O)c1cc(-c2cccc(OCC(C)C)c2)nn(C)c1=O +CC(C)c1nc(Cn2cnnn2)n(-c2ccc(Cl)cc2)n1 +Oc1ccc(N2CCN(CC(O)COc3ccccc3)CC2)cc1 +Cc1ccc(CCC2CCN(C(=O)c3nccnc3N)CC2)cc1 +Cc1nc(NCc2nc3c(s2)CCCC3)c2c(C)noc2n1 +CC1CCC(NC(=O)Nc2ccc(Cn3cccn3)cc2)CC1 +CCN(Cc1cccc2c1OCCCO2)CC(C)C#N +CCCCN(C)C(=O)c1ccc(OC(F)F)c(OC)c1 +Cc1ccc(-c2ccc(N)c(=O)n2C(C)C)cc1C +NC(=O)CCOc1ccccc1NC(=O)NCCO +Cc1ccc2c(CN(C)CC(=O)NCc3ccco3)cc(=O)oc2c1 +Cc1cc(C)c(C(=O)N2CCN(c3cccnc3)CC2)o1 +O=C(Nc1cn[nH]c1)c1ccc2c(c1)S(=O)(=O)N(C1CC1)C2=O +Cc1cccc(C)c1NC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +Cc1ccc(C(=O)CSc2ncccn2)cc1C +CC(=O)C(C)n1nc(C#N)cc1-c1ccc(C)cc1 +O=C(c1ccco1)N1CCC2(CC1)CCN(c1cccnc1)C2=O +COCCn1c(=O)c2c(nc3oc(C)cn32)n(C)c1=O +CC(Sc1ncnc(N)n1)C(=O)Nc1ccncc1 +CCOC(=O)c1noc(C(=O)Nc2c(C)cccc2C)c1N +O=C(CCn1ccc2ccccc21)Nc1ccnn1CC1CCOC1 +COc1ccccc1N1CCN(C(=O)c2cnc(C)cn2)C(C)C1 +Cc1noc(C)c1CN(C)C(=O)CCCc1cc(F)ccc1F +CC(C)S(=O)(=O)NCc1ccc(OCC(F)(F)F)nc1 +COc1ccccc1NC(=O)c1snc(C#N)c1N +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCc1nnc2n1CCCCC2 +N#Cc1cc2c(nc1N)N(Cc1ccco1)CC2=O +CC(C)N1CC(C(=O)OC(c2ccccc2)c2cccnc2)CC1=O +Cn1nc2c(c1NC(=O)C1CCCN(C(=O)OC(C)(C)C)C1)CCC2 +Cc1cccc(C2(C(=O)N3CCN(C4CCCC4O)CC3)CC2)c1 +COC(=O)c1ccc(NC(=O)c2cc(F)ccc2F)s1 +COCCNC(=O)N(C)Cc1nccn1CC(F)(F)F +O=C(c1nnsc1-c1ccccc1)N1CCOCC1 +Cc1ccc(NC(=O)CN(C)C(=O)c2c[nH]c3ccccc23)cc1 +CC(C)Oc1ccc(CNC(=O)c2cc(Cl)ccc2F)cn1 +CC(C)c1ccc(NC(=O)c2cc(N)c[nH]c2=O)cc1 +CCn1c(=O)oc2ccc(C(=O)Nc3ccc(C(C)=O)cc3)cc21 +Cn1c(=O)[nH]c2nnc(-c3ccc(C(F)(F)F)cc3)nc2c1=O +O=C(Nc1ccc2c(c1)OCO2)c1ccn(-c2ccc(F)cc2)n1 +O=C(OCCN1CCCC1=O)C1CC1c1ccccc1F +CSc1ccc(CN(C)S(=O)(=O)c2c(C)nn(C)c2C)cc1 +Nc1c(N2CCCCC2)ncnc1N1CCOCC1 +CC(Sc1nnnn1C(C)C)C(=O)NC(C)(C)C +Cc1nc(CNC(=O)N2CCN(c3ccccc3O)CC2)cs1 +COC(=O)C(C)N1CCc2c(OC)ccc(Br)c2C1 +CSc1ccc(C(O)CNC(=O)C2CC=CCC2)cc1 +CCOc1ccc(C2=CCN(C(=O)C3CCC(=O)N3)CC2)cc1 +CCn1nc(C(C)C)cc1C(=O)NC(C)CCc1ccco1 +Cc1ccccc1-n1nnc(C(=O)NCc2ccccn2)c1C +CC(=O)N1CCCn2nc(C(=O)N3CCC3c3ccccc3)cc2C1 +Cc1cnn(CCCNc2ccccc2S(=O)(=O)C(F)F)c1 +COc1cccc(N2CCN(C(=O)CCc3ccncc3)CC2=O)c1 +CCc1cc(C(=O)NC2CC2)nc2cc(-c3ccsc3)nn12 +CCOC(=O)CN(C(=O)c1c(F)cccc1F)C(C)C +CCOc1cc2c(cc1OCC)C(c1ccc(OC)cc1)CC(=O)N2 +Cc1cc(C)c(C(=O)Nc2ccc(NC(=O)C3CC3)cc2)c(=O)[nH]1 +CC(C1CC1)N(C)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +CCOc1ccc(C(=O)Nc2nnc(-c3ccnn3C)o2)cc1 +CC1(C)COCCN1C(=O)COc1ccc(CC#N)cc1 +Cc1ccccc1CNC(=O)CNC(=O)c1ccc(F)cc1F +O=C(c1cn(Cc2ccccc2)nn1)N1CCCC1C1CCCC1 +NC(=O)c1ccc(C#CCNC(=O)c2cnccn2)cc1 +Cc1ccccc1OC(C)CNC(=O)Cc1ccc[nH]1 +CCCC1CN(C(=O)c2cc3cc(F)ccc3oc2=O)CCO1 +Cc1ccc(NC(=O)Cn2c(C)nc3onc(C)c3c2=O)cc1 +Clc1cc(Br)ccc1OCCOCCn1ccnc1 +Cc1cc(C)c(C)c(C(O)CCCC(=O)N2CCCC2)c1C +CC(C)NC(=O)N(C)C1CS(=O)(=O)c2ccc(Cl)cc21 +O=C1c2ccccc2NC(c2cc[nH]n2)N1c1ccc(F)cc1 +O=C(Nc1nc(-c2cccnc2)cs1)C1CCCC1 +CS(=O)(=O)c1ccc(NC(=O)COc2ccccc2Cl)cc1 +CC1CN(C(=O)NCc2cccc(CN3CCCC3=O)c2)CCO1 +CC(C)(C)OC(=O)N1CCCC(COc2nccs2)C1 +CC(Nc1ccccc1)c1cccc(OCC(=O)N(C)C)c1 +O=C(NCCc1nc2c(s1)CCCC2)NC(CO)c1ccccc1 +O=C(Nc1ccccc1)N1CC(c2nc(-c3cccs3)no2)C1 +O=C(c1cc2ccccc2oc1=O)N(Cc1ccc(F)cc1)C1CC1 +CN(C(=O)Cc1ccc(Cl)cc1)C(C)(C)C#N +CC1CCCCC1NC(=O)Cn1cc(Br)c(=O)[nH]c1=O +CCN(CC)S(=O)(=O)NCc1ccc(C)s1 +COc1ccccc1NC(=O)CNc1ccc(NC(C)=O)cc1 +COc1ccc(NC(=O)N2CCc3ccccc32)c(OC)c1 +Cc1ccc(C(C)(C)C)cc1S(=O)(=O)NC1C=CC(CO)C1 +COC(=O)c1ccc(NC(=O)c2cc(-c3ccccc3)n[nH]2)cc1 +COCc1cccc(C(=O)NC(C)c2cccc(F)c2)c1 +Cc1nc(C(=O)N2CCC3(CC2)CC(OCC2CC2)CO3)cs1 +O=c1[nH]c(=O)n(CCOc2ccccc2C(F)(F)F)cc1Cl +Cc1ccc(Br)cc1-c1ncccc1N +COc1ccc2nc(C(=O)N3CCOCC3)cn2n1 +CC1CC1c1ccc(CNc2cnn(CC(F)F)c2)o1 +CCCCC(COC)NC(=O)Nc1ccc2c(c1)CCCN2C(C)=O +COc1nc(N(CC(N)=O)C2CCCC2)ccc1N +O=C(C1CCC1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 +CCC1CCCN(C(=O)Nc2ccccc2-n2cccn2)C1 +CCn1nc(C(=O)N2CCCC(n3nc(C)nc3C)C2)ccc1=O +COc1cccc2sc(NC(=O)c3ccnn3C)nc12 +CC(C)C(=O)NCCNC(=O)Cc1csc(-c2ccoc2)n1 +COCCCCNS(=O)(=O)c1ccc(C)cc1Br +O=C(NCc1ccncc1)Nc1ccc(OC(F)F)c2ncccc12 +O=C(CNc1ccc(N2CCCC2=O)c(F)c1)NCc1ccco1 +Nc1nc(N)nc(SCC(=O)N(C2=CCCCC2)C2CC2)n1 +O=C(Cc1cn2ccsc2n1)Nc1cc(-c2cccs2)n[nH]1 +CC(NS(C)(=O)=O)C(=O)N(C)Cc1ccccc1F +O=C(Nc1ccc2c(c1)CCO2)c1cc2ccccc2oc1=O +O=C(NCCCNc1ccc(C(F)(F)F)cn1)c1ccc(F)cc1 +CC(CO)(Cc1cccnc1)c1cccc(Cl)c1 +Cc1nc(NCc2ccccc2)c2nnn(Cc3ccccc3)c2n1 +COC(=O)c1ccc(S(=O)(=O)N=c2cc(C)cc[nH]2)cc1 +CC(C)(C)CCOC(=O)Cn1c(=O)[nH]c2ccccc2c1=O +Cc1cnn(CCC(=O)Nc2cc(-c3ncco3)ccc2C)c1 +N#Cc1nnn(-c2ccc(O)cc2)c1-c1ccc2c(c1)OCO2 +NC(=O)c1cccc(NCC(=O)Nc2cccc(C(N)=O)c2)c1 +COCc1cccc(NC(=O)N(C)CC2CCCC2)c1 +CN(C)C(=O)c1ccc(CNC(=O)c2cccs2)cc1 +Cc1cc(C)cc(NC(=O)Cn2cnc(C)c(C)c2=O)c1 +CN(Cc1ccsc1)C(=O)CSc1nncn1C +CCCn1ncc(-c2cc(C)ccc2F)c(N)c1=O +C=CCN(Cc1nc(-c2ccccc2)no1)C(=O)CNC(C)=O +O=C(CCC(=O)N1CCN(c2ccc(F)cc2)CC1)c1cccs1 +O=C(Cc1cccs1)OCCCc1cccnc1 +CN(CC(=O)c1ccc(O)cc1)C(=O)c1nc2ccccc2[nH]1 +N#Cc1ccc(S(=O)(=O)CCN(CCO)c2ccccc2)cc1 +COc1ccccc1CCNC(=O)c1sccc1C +NC(=O)c1ccc(Cl)cc1NC(=O)C1CC2CCC1C2 +O=C(Cn1cnc2ccccc21)Nc1ccc(Br)cc1F +Cc1cccc(C(=O)NCCS(=O)(=O)NCC2CCC2)c1 +CCCOC(=O)CCN1C(=O)C(C)Oc2ccccc21 +O=C1CN(c2ccc(NC(=O)c3ccc[nH]c3=O)cn2)CCN1 +COC(=O)c1sc(NC(=O)c2ccc(C)c(F)c2)nc1C1CC1 +Cn1c(C(=O)NC2CCCC2)nc2cc(N)ccc21 +O=C(NCc1cccnc1)NCC1(c2ccccc2F)CC1 +Cc1ccncc1NS(=O)(=O)c1cccc(N)c1C +C#CCN1CCC(C(=O)NCCC2CC3CCC2C3)CC1 +COc1cc(C(=O)Nc2cnccc2C)ccc1C +Cc1ccccc1OCCC(=O)N1CCCC(NS(C)(=O)=O)C1 +Cc1ccc(-c2nnn(CC(=O)N3CCCCCC3)n2)cc1 +CCCC(=O)N1CCCC(C(=O)Nc2ccc(C)cc2OC)C1 +CNc1nc(C(N)=O)c(NC(=O)Cc2ccc(OC)cc2)s1 +Cc1cc(C(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)c(C)s1 +Cc1cc(C(=O)N2CCCN(C(=O)c3ccncc3)CC2)on1 +COCc1cccc(C(=O)Nc2c(C)cnn2CC2CC2)c1 +Cc1cc(CNS(=O)(=O)c2c(C)noc2C)ccc1F +NC(=O)c1csc(C(=O)Nc2nc(-c3cccs3)cs2)c1 +COc1ccc(CC(C)CN(C)C(=O)NCc2cnn(C)c2C)cc1 +Cc1cc(C)c(CCn2nc(C)c(N)c2C)cc1C +COc1ccccc1N1CCN(C(=O)CNC(=O)C(C)(C)C)CC1 +CC1CN(C(=O)c2cnc(-c3ccccc3)nc2)CC(C)(C)O1 +CNc1snc(C)c1C(=O)NCc1ccc(Cl)cc1Cl +Cc1noc(C2CCCN(C(=O)NCC(C)C)C2)n1 +CC(=O)NC(C)C(=O)N(Cc1cccs1)Cc1cccs1 +O=C(NCCNc1ccc(-n2cccn2)nn1)Nc1ccccc1 +COc1ccc(NC(=O)N(Cc2ccc(C)o2)C(C)C)cc1OC +CCc1ccc(OCC(=O)Nc2cc(C)nn2CCC#N)cc1 +CCC1Oc2cc(CO)ccc2N(Cc2ccccc2)C1=O +CCn1ccc2ccc(NC(=O)NCC(C)C)cc21 +Cc1csc(C(OC(=O)CC2CCCC2)C(F)(F)F)n1 +CC(=O)c1ccc(NC(=O)c2cccn2C)cc1C +CC1(c2ccccc2)CCC(=O)N(CCCN2CCOCC2)C1 +CCCc1nc2[nH]c(C)c(Cc3ccccc3Cl)c(=O)n2n1 +Cc1cc(C)c(CNC(=O)C(C)n2ccnc2)c(C)c1 +Fc1cc(F)c2nc(NCC3CCCO3)sc2c1 +COc1cccc(CNc2cccc(S(N)(=O)=O)c2)c1 +N#CC1(c2cccc(C(F)(F)F)c2)CCC(=O)CC1 +Cc1cc(C(=O)Nc2nnc(C(C)C)s2)c2cnn(C(C)C)c2n1 +CC1CN(c2ncc(N)cc2Br)CC(C)O1 +Cc1ccc(C)c(OC(=O)COc2ccc(C(N)=O)cc2)c1 +CC(=O)c1ccc(NCc2cccc(C(=O)NCc3ccco3)c2)cc1 +COc1cccc(C(=O)Nc2ccc3sc(C)nc3c2)c1OC +O=C(Cn1cc(-c2ccncc2)cn1)Nc1ccnn1Cc1ccco1 +NC(=O)N1CCCC(C(=O)Nc2cccc(CO)c2)C1 +Oc1ccc2c(c1F)C(c1ccc3c(c1)OCO3)NCC2 +CC(C)(CNC(=O)NC1(c2ccccc2F)CC1)N1CCOCC1 +Cc1nc2sc(C(=O)OCC(=O)NC3CCCC3)c(C)c2c(=O)[nH]1 +CN(Cc1ccc(C(N)=O)cc1)C(=O)c1ccccc1Br +CCC(C)OC(=O)CC1C(=O)NCCN1C(=O)Cc1ccccc1 +CCc1nc2nccc(-c3ccc(OC)cc3)n2n1 +CCN1C(=O)C(Cc2ccc(C)c(C)c2)Oc2ccc(N)cc21 +CC(=O)Nc1nc(Cn2nnc(-c3ccc(F)c(C)c3)n2)cs1 +Clc1cccc(-c2ccnc3nc(-n4cccc4)nn23)c1 +COc1cc(C#N)ccc1OCCN1C(C)COCC1C +COc1ccc(Cc2nnc(SCC(N)=O)n(C)c2=O)cc1 +O=C(NCCc1ccc(F)cc1)c1nc(-c2cnccn2)no1 +CC(Sc1n[nH]c(N)n1)c1nc(C(C)(C)C)no1 +Cc1cccc(Cn2cc(NS(=O)(=O)c3ccc(F)cc3)cn2)c1 +CCc1onc(C)c1NC(=O)N1CCCC(C(=O)NC)C1 +O=C(OCC(=O)N1CCc2ccccc21)C1CCCN1C(=O)C1CC1 +Cc1cc(C(O)CNS(=O)(=O)c2ccccc2)ccc1F +CC(Oc1ccccc1)C(=O)N1CCCN(c2cccnn2)CC1 +CCNC(=O)c1ccc(C)c(NC(=O)CSc2ccccc2)c1 +COc1ccccc1Nc1ncc(Br)cc1N +CCn1nc(C)c(CNC(=O)N(C)Cc2ccc(OC)c(C)c2)c1C +CCC(=O)N(Cc1nccn1Cc1ccc(F)cc1)C(C)C +COc1ccc2c(c1)N(C(=O)Cc1ccc(F)cc1F)CCO2 +O=C(OCC(=O)C1CC1)c1ccc(-n2cnc3ccccc32)nc1 +COc1cccc(C(=O)N2CCN(c3ccccc3C#N)CC2)c1 +CC(Cc1cccc(Cl)c1)NC(=O)c1c[nH]c2ccccc2c1=O +CCN(CC)S(=O)(=O)NC1CC2CC1C1CCCC21 +COCCOCc1cccc(NC(=O)N2CCCC(C)C2)c1 +Cc1noc(COCC(=O)Nc2ccnn2C2CCCCC2)n1 +N#Cc1ccc(OCCNC(=O)Nc2cccnc2)cc1 +COCCC(=O)N1CCC2(COCc3cnc(N(C)C)nc32)C1 +CCCc1n[nH]c(C2CN(C3CC(C)OC3=O)CCO2)n1 +CNC(=O)c1cccc(NCCOc2ccc(OC)cc2)c1C +CCNC(=O)N1CCN(CCOc2c(C)cccc2C)CC1 +Cc1nnc(NC(=O)CS(=O)(=O)c2ccc3ccccc3c2)s1 +CC1CN(C(=O)Cn2ccnc2)CC1c1nc(-c2ccncc2)no1 +Cc1csc(C(C)NC(=O)NC(C)(C)c2nc(C)c(C)s2)n1 +COc1ccc2cc(C(=O)N3CC(C)OC(C)C3)[nH]c2c1 +COCCS(=O)(=O)N(C)c1ccccc1C(=O)OC +Cc1ccccc1OCC(=O)Nc1ccc2c(c1)N(C)C(=O)C(C)O2 +Cn1ccc(CNC(=O)c2c(Br)cnn2C)n1 +C#CCNC(=O)Cc1ccc(NC(=O)c2cc3ccccc3o2)cc1 +Nc1cc(-c2ccco2)nn(CC(=O)Nc2ccccn2)c1=O +N#CCCN(CCC#N)C(=O)c1ccc(-n2ccnn2)cc1 +CSc1ccccc1C(=O)NCc1nnc2ccccn12 +CCOC(=O)CCCC(=O)c1ccc(C)c(Cl)c1 +CCOc1ccc(C(=O)Nc2ccc(C(N)=O)c(Cl)c2)cc1 +CCN(CC(F)(F)F)S(=O)(=O)c1sc(=O)[nH]c1C +O=C(NCc1cccc(O)c1)c1ccccc1C(F)(F)F +c1cc(CCCNc2ccc3cn[nH]c3c2)ccn1 +CCc1cc(CNC(=O)C(N)Cc2ccccc2)ccc1OC +CC(=O)N1CC(C(=O)Nc2cccc(C)n2)Oc2ccccc21 +Cn1cc(NC(=O)Nc2ccccc2C(N)=O)c2ccccc2c1=O +Cc1nn(-c2ccccc2)c(C)c1CN1CCN(CC(F)F)CC1 +COc1ccc(C(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)nn1 +COc1ccc(C(O)C(C)NC(=O)C2CN(C)CCO2)cc1 +COc1cc2[nH]c(=O)c3sc4ccccc4c3c2cc1OC +CN(C)C(=O)CN(C)C(=O)CSc1cccc(C(F)(F)F)c1 +O=C(c1scnc1C1CC1)N(Cc1ccco1)c1ccccn1 +Cc1cc(=O)n2nc(Oc3cccc(C)c3C)sc2n1 +CCC(C(=O)N1CCCC(c2nncn2CC)C1)c1ccccc1 +Cc1cccc(C(=O)NCc2noc(-c3cccs3)n2)c1 +COc1cccc(C(=O)N(C)C(C#N)c2ccccc2)c1 +CN(C(=O)CCCOc1ccc(S(C)(=O)=O)cc1)C1CCCC1 +O=C(CSc1nncn1C1CC1)Nc1cccc(CO)c1 +Cn1cc(C(=O)Nc2cccc(OCc3ccc(F)cc3)c2)cn1 +Cc1cc(C)c(C)c(S(=O)(=O)NCC(O)c2ccsc2)c1C +C=CCN(CC=C)C(=O)COc1cccc(C#N)c1 +CCC(Oc1ccccc1C)C(=O)Nc1sc(C)c(C)c1C(N)=O +Nc1ccc(-c2nc(-c3ccc4c(c3)OCO4)cs2)cc1 +OCc1c(-c2cccnc2)nc2cc(C(F)(F)F)ccn12 +CN(C)C(=O)N1CCC(C(=O)Nc2ccc(F)c(C#N)c2)CC1 +NC(=O)c1cccc(NC(=O)CC2OC(=O)c3ccccc32)c1 +Cc1nn(C)c(C)c1CC(=O)N(C)CC1COc2ccccc2O1 +CCOc1c(Cl)cccc1NC(=O)C(C)n1cccn1 +COc1ccc(NC(=O)Cn2cc(C(=O)C3CC3)c3ccccc32)cc1 +COCCNC(=O)c1cc(-c2ccc(OC)cc2)nc2ccccc12 +CNc1nc(-c2cc3c(n(C)c2=O)CCC3)cs1 +CCn1c(=O)n(CC(=O)OCC2CC2(Cl)Cl)c2ccccc21 +CCOc1cccc(C(C)NC(=O)Nc2ccccc2CC(N)=O)c1 +CC(C)c1n[nH]c(C(=O)Nc2cccc3cn[nH]c23)c1Br +CC(c1ccccn1)N(C)C(=O)Nc1cccc(OC(F)F)c1 +O=C(Cc1ccc2c(c1)OCCO2)Nc1ccc(F)cc1 +O=S(=O)(NCC1CCOC1)C1=Cc2ccccc2CC1 +COC(=O)c1cc(NS(=O)(=O)c2cccc(F)c2)ccc1Cl +COCc1ccccc1CNC(=O)NCc1ccc2c(c1)OCO2 +O=C(C(c1cccnc1)N1CCCC1)N1CCC2(CCCO2)CC1 +C=CCn1c(N)nnc1SCc1cc(C)c(C(=O)OC)o1 +CC(C)c1nc(NCc2nnc3n2CCC3)nc(N(C)C)n1 +CC1CCOC1C(=O)N(C)c1cccc2ncccc12 +CCNC(=O)c1cccc(NC(=O)COc2ccc(OC)cc2)c1 +Cc1ccc(OC2CCN(C(=O)c3cccn(C)c3=O)CC2)cn1 +CNC(=O)CN1CCN(C(=O)c2cc(F)cc(F)c2)CC1 +Cc1ccc(C(O)CCC(=O)NCC2CCCO2)cc1C +Cc1noc(C)c1CC(=O)OCCn1c(=O)oc2ccccc21 +O=C(c1ccco1)N1CC2CCCC2(COc2cccnc2)C1 +CC(C)Cn1ncc(C(=O)N(C)c2ccc(F)c(F)c2)c1C1CC1 +O=C(COc1ccc(OCc2ccccc2)cc1)Nc1nncs1 +COCCCn1ccc(Nc2nc(-c3ccncc3)nc(C)c2C)n1 +CC1CN(C(=O)NC2CCN(C(=O)c3ccoc3)CC2)CC(C)O1 +Fc1cccc2c1CCNC2c1cnc2ccccc2n1 +Cc1ccc(C)c(-n2c(C)nnc2SCC(=O)N2CCC(O)C2)c1 +NS(=O)(=O)c1ccc(C(=O)N2CCCC2)cc1 +COCc1c(C(=O)Nc2cccnc2N(C)C)oc2ccccc12 +COc1ccc(F)cc1NC(=O)c1cc(-c2ccccc2)no1 +O=C(C1CCN(c2cnc3nccnc3c2)CC1)N1CCCCC1 +Cc1nnnn1C(Cc1cccc(F)c1)C(=O)NCC1CCC1 +COc1ccc(NC(=O)CCNC(=O)c2ccco2)cc1OC +Nc1c(Nc2cccc(C(F)(F)F)c2)ncnc1Oc1cccnc1 +Cc1c(C(=O)OCCN2CCCC2=O)nnn1-c1cccc(Cl)c1 +CC(NS(=O)(=O)c1ccc(OC(F)(F)F)cc1)C(N)=O +COc1ccc(CC(=O)N2CCC(c3cccs3)CC2)cc1 +O=C(CSc1nc(-c2ccccc2)ns1)N1CCOCC1 +CCOCC(=O)N1CCC(CSc2ccccc2)C1 +CCc1noc(-c2c(C)[nH]c(C)c2S(=O)(=O)N2CCCCC2)n1 +CC(C)=CCN1CCn2ncc(C(=O)NCC(C)C)c2C1 +O=C(Cn1nc2ccccn2c1=O)NC1CCOCC1 +CCOC(C)c1nc(COc2cccc(C(C)=O)c2)cs1 +COc1ccc(F)cc1NC(=O)NC(C)c1nc2ccccc2[nH]1 +COc1cccc(OCC(=O)N(Cc2ccccc2)C2CC2)c1 +Cc1ccc(NC(=O)c2cnc3onc(C(C)C)c3c2)nc1 +C#CCN1CCN(C(=O)NCC(C)(C)N2CC(C)OC(C)C2)CC1 +C=CCNS(=O)(=O)c1ccc(OC)c(Br)c1 +CC(=O)N1CCc2cc(C(=O)Nc3ccccc3N3CCCC3)ccc21 +CC(=O)Nc1ccc(F)c(C(=O)NC(C)COc2ccc(F)cc2)c1 +CCCS(=O)(=O)Nc1ccc2c(c1)N(S(C)(=O)=O)CCC2 +CC(C)Nc1cccc(CNC(=O)Cn2ccccc2=O)c1 +Cc1nnc(NC(=O)c2csc(-c3ccc(Cl)cc3)n2)s1 +COc1ccccc1CC(=O)NCCc1ccc(F)cc1 +O=C(CCSc1ccc(F)cc1)NCc1cscn1 +CC(C)C(NC(=O)c1cccs1)C(=O)OCC(F)(F)F +O=C(c1cc(F)ccc1C#CCO)N1CCC(O)C1 +CCOC(=O)NCCOc1cc(N2CCCCC2)nc(C)n1 +COCN1CC(C)Nc2cc(Br)ccc21 +Cc1nn(CC(O)c2cc(F)ccc2F)c(C)c1Br +COc1ccc(C(=O)NCc2ccc3c(c2)OCO3)c(OC)c1 +CCOc1ccc(C(F)(F)F)cc1NC(=O)NC(C)(CO)C1CC1 +CC(=O)Nc1ccc(O)c(C(=O)N2CCC(n3cccc3)CC2)c1 +COc1cccc(Nc2ncc(Br)cc2N)c1 +CC(COc1ccccc1)OC(=O)c1ncn(-c2ccccc2)n1 +CCOC(=O)c1c(C2CC2)csc1NC(=O)C1CC1 +CC(Sc1ccccc1)C(=O)NCc1cc(C(C)C)no1 +CN(C(=O)c1cccc(CSc2nccn2C)c1)C1CCCC1 +CCCOCC(=O)NCc1nc(-c2ccncc2)cs1 +COc1ccc(NC(=O)C(C)Oc2ccc(-n3cnnn3)cc2)cc1 +CCn1cc(C(=O)NCc2ccc(OC)c(C)c2)cn1 +CCC(c1ccc(OC)cc1)N(C)C(=O)c1cnc2ccccn12 +COCC(C)NC(=O)CCS(=O)(=O)c1ccccc1 +CC(C)N(C(=O)c1ccc(C(F)(F)F)cc1)C1CCC1 +CCCNC(=O)NCc1ccc(OCC)c(OC)c1 +CC(C)C1CCCN(C(=O)c2ccc(-n3ccnn3)cc2)CC1 +Nc1ccccc1CCC(=O)Nc1cccc(OCC2CCCO2)c1 +CCC(NS(=O)(=O)c1cc(C)cc(F)c1)C(=O)OC +Cc1ccc2nc(COC(=O)c3ccccc3F)cn2c1 +COc1ccccc1CNC(=O)CNC(=O)c1cc(C)nn1C +O=C(Nc1ccc(Cl)c(Cl)c1)N1CCCCC1CO +CCOc1ccc(C(C)NC(=O)c2ccccc2S(C)(=O)=O)cc1 +CC(c1ccccc1)n1cc(C(=O)NCc2ccncc2)nn1 +CN(C)C(=O)c1cccc(C(=O)NCC(C)(O)c2ccc(F)cc2)c1 +CSc1ccc(NC(=O)N(C)CC(C)C)cc1 +Cc1ccc(-c2ocnc2C(=O)NCCc2ccccc2)s1 +CC(C)C(NC(=O)c1cccn2cncc12)C(=O)N1CCCCC1 +Cc1nc(-c2ccccc2)c(C(=O)Nc2nc3c(s2)CCC3)s1 +Clc1cnccc1CN1CCN(c2cccs2)CC1 +COc1cc(NC(=O)N(C)C(C)c2ccccn2)ccc1NC(C)=O +CN(C(=O)c1ccc(Br)cc1)C1Cc2ccccc2C1 +O=C(Nc1cc(C(F)(F)F)ccc1F)N1CCCC1 +COc1ccc(C)cc1CCNC(=O)c1ccsc1 +COCCCN(C)S(=O)(=O)c1ccc(C#N)cc1 +O=c1onc(-c2cccc(Br)c2)n1CC1CCOC1 +O=S(=O)(Nc1ccccc1)c1ccc(CO)cc1 +CCCc1cc(C(=O)N2CCC2c2cccs2)no1 +CCC1COCCN1Cc1cc(C)c(OC)c(C)c1 +COC(=O)C1CCN(C(=O)c2cnn(-c3ccccc3Cl)c2)CC1 +Cc1n[nH]cc1CNc1cnc2c(c1)c(C)nn2C +CC(C)CN(CC(O)c1ccc(F)cc1)C(=O)c1csnn1 +CCC(=O)N1CCC(NC(=O)Nc2ccccc2)CC1 +COC(=O)c1ccc(S(=O)(=O)Nc2cccc3[nH]ncc23)o1 +CCc1nnc(NC(=O)C2C(C=C(C)C)C2(C)C)s1 +COc1cccc(OC)c1C(=O)NCCC(N)=O +NC(=O)CSc1nnc(-c2cc3ccccc3[nH]2)o1 +CCOC(=O)N1CCC(NC(=O)Cc2coc3cc(C)ccc23)CC1 +CCCCN(C)C(=O)c1snc(-c2ccccn2)c1N +O=C(Nc1ccccc1)c1cccc(OCC(F)F)n1 +CCCN(C)C(=O)NC1CCN(c2c(F)cccc2F)C1=O +Cc1csc(C(C)CNC(=O)NC(C)C2CCOC2)n1 +O=C(Cn1ccc2ccc(F)cc21)Nc1ccc2cc[nH]c2c1 +COc1cccc2cc(C(=O)Nc3ccc(F)cc3)c(=O)oc12 +CCOC(=O)N1CCN(c2nc(C)c(N)c(C)n2)CC1 +CCCCOCC(=O)NC(C)c1nc2cc(Cl)ccc2[nH]1 +CCc1ccccc1CNC(=O)NCc1cccc(Cn2cccn2)c1 +CCOc1ccc(F)c(C(=O)NC(C)(C)CC)c1F +COCCOc1cccc(C(=O)Nc2cccc(C)n2)c1 +NC(=O)c1c(NC(=O)CSc2ncn[nH]2)sc2c1CCC2 +Cc1cc(C)c(CNC(=O)c2cc3cc(Cl)ccc3o2)c(=O)[nH]1 +CCc1ccccc1NCc1nnc(-c2ccccc2)o1 +O=C(Nc1cccc(Cl)c1N1CCOCC1)c1ccccc1F +CCOc1ccc(NC(=O)c2cnn(C)c2-n2cccc2)cc1 +CCOc1nccnc1N1CCC(NS(C)(=O)=O)C1 +Cc1cc(C)n2nc(C(=O)Nc3cccc(S(C)=O)c3)nc2n1 +CC(=O)c1c(C)[nH]c(C(=O)OCc2cc(F)cc3c2OCOC3)c1C +CS(=O)(=O)c1ccc(OCCNC(=O)c2ccco2)cc1 +CCC(=O)Nc1cccc(C(=O)N2CC(C)CC(C)C2)c1 +COc1ccc(Cl)cc1-n1c(=O)c(N)c(C)n1C +CC(C)NC(=O)CCNc1cccc(C(F)(F)F)c1 +CC1CC1C(=O)Nc1ccc(S(=O)(=O)CC2CCCO2)cc1 +CC1CN(C(=O)C2CCCO2)CC12CCN(c1cccnc1)C2=O +COc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1Cl +Cc1cc(C(C)NC(=O)C2CNC(=O)C2)c(C)s1 +CC(=O)c1scc(Br)c1Br +Cc1nc(NC(=O)c2cccc(OCC3CCCO3)c2)sc1C +N#CCc1ccc(NC(=O)c2cccc(F)c2)cc1 +CC(C)N1CC(C(=O)Oc2ccc(OCC3CC3)cc2)CC1=O +CCCCSc1nc(N)c(NC(=O)c2ccc(F)cc2)c(=O)[nH]1 +O=C(c1ccoc1)N1CCN(c2ccccc2O)CC1 +O=C(OCCOc1ccccc1F)c1cn(-c2ccccc2)nn1 +Cc1cccc(OCc2nnc3n(C)c(=O)c4ccccc4n23)c1 +O=C(Cc1c(F)cccc1Cl)N=c1[nH]nc2ccccn12 +CCCn1c(CCCNC(=O)C2CC2)nc2ccccc21 +CCCN(CC(=O)OCC)C(=O)c1ccoc1C +Cc1nc2ccc(NC(=O)Nc3cnn(C)c3)cc2s1 +CC(=O)c1ccc(OC(=O)CCn2c(C)csc2=O)cc1 +COc1csc(C(=O)NCC(=O)NCc2ccccc2)c1 +CC(C)OC(=O)c1cccnc1N1CCN(c2ccccc2F)CC1 +Cc1csc(=O)n1CC(=O)N(C)c1ccc2ccccc2c1 +CN(Cc1ccc2nonc2c1)C(=O)CC1NC(=O)c2ccccc21 +COc1ccc(NC(=O)C(C)C)cc1OCc1ccncc1 +Cc1nnc(SCc2nccc(N)n2)n1CCc1cccs1 +CCCNC(=O)CNC(=O)Nc1ccc(OC(C)C)cc1F +O=C(NCc1ccccc1Cl)c1cc(C(F)(F)F)n[nH]1 +O=C(Nc1ccccc1)c1ccc(-n2cccn2)cc1 +c1ccc2oc(NCCc3nnc4ccccn34)nc2c1 +CC(=O)N(C)Cc1ccc(C(=O)Cn2nnc(-c3ccccc3)n2)cc1 +COC(=O)c1cnc(N(C)C(=O)c2scnc2C2CC2)s1 +CN(Cc1ccccc1)Cc1cc(=O)c(O)cn1CCO +c1cnn(CC2CCCCN2Cc2nnnn2C2CC2)c1 +O=C(Nc1ccccc1)n1[nH]c(-c2ccccc2)cc1=O +CCc1ccc(CN(C)C(=O)c2ccc(COC)cc2)cc1 +O=C(NCCCC(=O)N1CCCC1c1ccc[nH]1)c1ccco1 +COc1cc(OC)cc(C(=O)NC(C)c2ccc(NC(N)=O)cc2)c1 +CCOC(=O)c1ccccc1NC(=O)c1ccc2c(c1)OCO2 +Cc1cc(C)c(CNC(=O)Nc2nnc(C(F)(F)F)s2)c(C)c1 +CCOC(=O)CN(C(=O)Cn1cnc2ccccc2c1=O)C1CC1 +CN(C)C(=O)CNC(=O)Nc1ccc(Cl)c(Cl)c1 +Cc1nc(CNC(=O)c2scnc2C2CC2)sc1C +O=C(NCC1CC12CCc1ccccc12)c1n[nH]c(=O)c2ccccc12 +CCOCC(=O)NCc1cc(C(=O)OC)c(C)o1 +O=C(N1CCCCC1)C1(c2cccs2)CCOCC1 +COc1ccc(N(C)C(=O)COCC2CC2)cn1 +CN(C)C(=O)CNC(=O)CC1Sc2ccc(Cl)cc2NC1=O +CCSc1nc2nn(-c3ccccc3)c(=O)c-2c2n1CCCCC2 +Cc1nnc(CSc2nc(-c3cccs3)nc3ccccc23)o1 +CCN(C(=O)CN(C)C(=O)c1ccccc1)C(C)c1ccc(C#N)cc1 +Cc1nc2ccc(N)cc2n(Cc2ccccc2F)c1=O +O=C1COC2(CCN(c3ncccn3)CC2)CN1c1cccnc1 +CC1CCCCC1N(C)C(=O)C1CC(=O)N(C2CC2)C1 +Cc1cccc(C(=O)NCCNC(=O)c2cccnc2)c1 +Nc1cc(Cl)c2oc(C(=O)NC3CC3)cc(=O)c2c1 +CCS(=O)(=O)N1CCC(c2nnc3n2CCC3)CC1 +CN(CCc1cccc2ccccc12)C(=O)CCn1ccccc1=O +C=CCNC(=O)Nc1cccc(Cn2nc(C)cc2C)c1 +CCC(C)c1cc(C(=O)Nc2ccc(Oc3cccnc3)nc2)on1 +O=C(NCC(O)c1cccc(F)c1)c1cc(Br)c[nH]1 +CCOC(=O)c1c(NC(=O)OC)sc2c1CCCC2 +CN(CCc1ccccc1)CC(O)CN1CCOCC1 +CCCCNC(=O)C(C)Sc1nc(C)nc(C)c1C#N +CCC(CO)N(Cc1cccs1)C(=O)c1cnccc1C +COc1cc(C(=O)N2CC(C)CC(C)C2)cc(Cl)c1OC +COc1ccc(NC(=O)C2CC(=O)OC2(C)C)c(OC)c1 +COC(=O)c1cc(CN2CCNC(=O)C2)c(C)s1 +CCc1nsc(N2CCCC(S(=O)(=O)NC3CCCC3)C2)n1 +COc1cccc(CCNC(=O)c2cncc(Br)c2)c1 +Cc1ccc(OCCCCNC(=O)c2ccnn2C)cc1 +COc1ccc2c(c1)C(=O)Nc1cc(Cl)ccc1N2 +CCN(CC)C(=O)C1CCCN1C(=O)CCc1c[nH]c2ccccc12 +O=C(N1CCCCC1)N1CCN(c2ncccc2F)CC1 +CCc1ccsc1C(=O)N(C)Cc1cccc(C#N)c1 +COc1ccc2c(c1)C(c1ccc(F)c(OC)c1)NCC2 +COC(=O)CC(C)NC(=O)c1cccn1Cc1ccccc1 +COC(=O)C(C)CN(C)Cc1c[nH]nc1-c1ccc(C)cc1 +CN(C)C(=O)N1CC2CCC(C1)N(C(=O)c1cnc[nH]c1=O)C2 +O=C(Nc1nnc2n1CCS2)c1cc(Cl)ccc1Cl +Cc1c(NC(=O)CCc2cccs2)c(C(=O)N(C)C)nn1C +CN(CC(=O)NCc1ccncc1)c1nc2c(Cl)cccc2s1 +CCc1nnc(NC(=O)CN2CCCCC2=O)s1 +CC(C)C(NC(=O)COc1ccccc1C(N)=O)c1ccccc1 +CC(=O)c1cccc(NC(=O)CNc2ccccc2F)c1 +CCCN1C(=O)Cc2ccccc2C1C(=O)NCc1ccccc1C +CCc1nnc(COc2ccc(S(=O)(=O)N(C)C)cc2)o1 +CCCS(=O)(=O)N1CCC(NC(=O)NCc2cscn2)CC1 +O=C(NCC1CCOC1)N1CCc2ccccc2C1 +COc1ccc(C(=O)N2CCN(c3nc4ccccc4o3)CC2)cc1 +COc1ccc(Cl)cc1CNC(=O)C1CC2C=CC1C2 +Cn1cc(C(=O)NCCCN2CCOCC2)ccc1=O +CCOc1ccccc1CN(C)C(=O)c1c[nH]c2cccc(F)c12 +Cc1nnc(CSc2ncc(-c3ccccc3)n2-c2ccccc2)o1 +Cc1cc(C(=O)CNC(=O)c2cccc(Cl)c2)ccc1F +CC1CN(C(=O)c2cc(F)c(N)c(F)c2)CCO1 +CC(=O)Nc1ccc(CNC2(Cc3cc(CO)on3)COC2)cc1 +Cc1ccncc1NC(=O)N(C)Cc1ccoc1C +COc1ccccc1C(C)N(C)C(=O)c1cn2cccnc2n1 +CCc1cc(C(C)NC(=O)c2ccc(-n3nc(C)cc3C)cc2)on1 +COc1ccc(OC(=O)C2CC3CCC2O3)c(C(C)=O)c1 +COc1cc(C#N)ccc1OC(C)C(=O)N(C)c1ccccc1 +CC(NC(N)=O)C(=O)OCC(=O)Nc1ccc2c(c1)CCC2 +CC(C)C(=O)N1CCC(NC(=O)C2CC=CCC2)CC1 +O=C(COc1cc(=O)n2ccccc2n1)NCc1ccc(F)cc1 +COc1ccc(CNC(=O)NCc2ccco2)cc1F +Cc1cccc(C(=O)NC(C)c2nc3ccccc3[nH]2)c1 +CC(C)(C)OC(=O)N1CCN(c2cc(N)ncn2)CC1 +CC(C)CN1CCOC(CNC(=O)CCn2ccc3ccccc32)C1 +CN(Cc1ccc(C#N)cc1)C(=O)NCCC(=O)NC1CCCC1 +Cc1occc(=O)c1OCC(=O)NC(C)c1ccccc1 +CCC(C)NC(=O)CCCN1C(=O)COc2ccc(C)cc21 +COc1ccc(C(=O)Nc2ccc(Cl)cc2N)cc1OC +Cc1ccc(C(=O)Nc2cc(N)ccc2F)s1 +C#CCOC(=O)c1cc(S(=O)(=O)N(C)C(C)C)ccc1Cl +Nc1c(NCCc2ccccc2)ccc2scnc12 +O=C(CCc1n[nH]c2c1CCCC2)N1CCCC2(CCOC2)C1 +CCOCC(O)CN1CCN(C(=O)C2CC(=O)N(CC)C2)CC1 +COc1ccccc1N1CCN(Cc2nnnn2C2CC2)CC1 +O=C(CCCc1c[nH]c2ccccc12)N1CCCCC1c1ncc[nH]1 +Cn1ccnc1N1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +Cc1ccccc1Cn1cc(NS(C)(=O)=O)cn1 +CCOC(=O)C(C)S(=O)(=O)c1ccc(O)cc1 +Cc1cc(C)cc(C(=O)N2CCC(NS(C)(=O)=O)CC2)c1 +COc1ccc(C(=O)NC(C)c2nc3cccnc3n2C(C)C)cc1 +COc1ccc(CNC(=O)C2COc3ccccc3C2)c(OC)c1 +Nc1ccc2ccnc(C(=O)Nc3nccs3)c2c1 +Cc1sc(=O)n(CC(=O)Nc2nc3c(C)cccc3s2)c1C +O=C1c2ccccc2NC(c2ccccn2)N1CC1CCCO1 +CC(C#N)CN(C)C(=O)c1cn(C)c2ccccc12 +CSc1cc(C(=O)Nc2sc(C)c(C)c2C(N)=O)ccn1 +Cc1csc(C(N)c2cccc(Br)c2)n1 +C#CCNC(=O)c1ccccc1NC(=O)COC1CCCCC1 +O=C(Nc1ccccc1F)C1CC2CCCC(C1)C2=O +CS(=O)(=O)c1ccc(C(O)c2cccs2)cc1 +CCOc1ncnc(NCCN2CCOCC2)c1N +O=S(=O)(c1ccc2cccc3c2c1CC3)N1CCOCC1 +CCOC(=O)C1CCN(c2ncccc2C(N)=O)CC1 +COCCc1nnc2n1NC(c1ccccc1OC)CS2 +Cn1c(NC(=O)CCC2CCCC2)cc(=O)n(C)c1=O +O=C(CCc1nc(-c2ccccc2)no1)N1CCCCC1 +Cn1ncc2c(N(CCO)C3CCCC3)ncnc21 +Cc1cccc(Cn2c(=O)cnc3ccccc32)c1 +C=CCNC(=O)CCNC(=O)N1CC(=O)Nc2ccccc21 +CC(Cc1cccc(Cl)c1)C(=O)N1CCC(c2cnn(C)c2)CC1 +CSc1ccsc1C(=O)N=c1[nH]nc2cc(C)ccn12 +Cc1cc(C(=O)NCc2c(C)nn(C)c2C)c2cnn(C)c2n1 +CC(C)Oc1ccc(C#N)cc1NC(=O)N1CCCC1 +CCN(CC)S(=O)(=O)c1ccc(=O)n(CC(=O)C(C)(C)C)c1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)Nc1cc[nH]n1 +Cc1cc(C)nc(N2CCCC(C(=O)NC3CCOC(C)(C)C3)C2)n1 +CCCS(=O)(=O)N(C)Cc1cc(C#CCCO)cs1 +Cc1nc(C2(NC(=O)CN3CCc4ccccc43)CCCC2)no1 +Cc1nn(-c2ccc(NC(=O)C(C)C)cn2)c(C)c1Cl +CN(Cc1ccccc1)S(=O)(=O)NC1CCCC1 +O=C(c1ccccc1)N1CCN(c2nnc3ccccn23)CC1 +Cc1cnn(CCC(=O)NC(c2ccc(Cl)cc2)C(F)(F)F)c1 +N#CCc1nc2ccc(F)cc2n1CCN1CCOCC1 +CC(=O)Nc1cccc(COC(=O)CCc2cc(Cl)cs2)c1 +NC(=O)c1ccsc1NC(=O)CCN1CCOCC1 +O=S(=O)(c1c(F)cccc1Br)N(CCO)C1CC1 +Cn1cc(C(=O)Nc2sc3c(c2C#N)CCCC3)cn1 +COc1cccc(C2(CNS(=O)(=O)CC3(C#N)CC3)CCCC2)c1 +O=C(OCc1nc2ccccc2[nH]1)C1CC(=O)N(CC(F)(F)F)C1 +Cc1ccc(N2CCC(C(=O)NCC(C)C)C2=O)cc1C +CCCOC(=O)c1ccc(NC(=O)c2nc3nccc(C)n3n2)cc1 +Cc1nnc(-c2cccc(C(=O)NC3(c4ccccc4)CC3)c2)o1 +Cc1cc(C)c(C(=O)Nc2ccc3c(c2)CCC3)c(=O)[nH]1 +O=C(COc1ccc(F)c(Cl)c1)Nc1ccc2c(c1)OCCO2 +Cc1ccc(SCC(=O)NCc2cccnc2)cc1C +Cc1cc2c(c(=O)[nH]1)C(c1ccnn1C)CC(=O)O2 +COc1ccc(OC)c(CNc2ncnc3c2nc2n3CCCC2)c1 +CCOc1ccc(C(=O)Nc2cccc(SC)c2)cc1OC +COc1cc(C(=O)Nc2ccc(SC)cc2)cc(OC)c1OC +O=C(NCc1ccsc1)NCC1(c2ccccc2)CC1 +CCn1c(SC(C)C(N)=O)nc2sc(C)c(C)c2c1=O +c1cnn(-c2ccc(-c3noc(C4CCCCC4)n3)cn2)c1 +CCCOC1C(C2COC(C)(C)O2)OC2OC(C)(C)OC21 +CC(=O)c1ccc(NC(=O)CC2CCOc3ccccc32)cc1C +O=C(OCCNc1ncccn1)c1cccc2cn[nH]c12 +CCOC(=O)CCn1cnc2sc(C)c(C)c2c1=O +COc1ccccc1C(NC(=O)c1cc[nH]n1)C(C)(C)C +CC(NC(=O)C1CCCO1)c1cccc(Br)c1 +CSc1ccc(C(=O)CSc2nnc(C)n2C)cc1 +O=C(CCn1cncn1)Nc1ccc2c(c1)NC(=O)CO2 +CC(OC(=O)c1cccc(N(C)C)c1)c1nc(-c2cccnc2)no1 +CCc1n[nH]c(=O)c(CNC(=O)Nc2ccc(F)cc2)c1CC +Cc1noc(CCC(=O)NCc2ccc3ccccc3c2)n1 +CCOCCCNC(=O)c1c(F)cccc1Cl +COC(=O)c1sc(NC(=O)CCc2ccccc2Cl)nc1C +CCc1nc(-c2ccc3c(c2)CCC(=O)N3)cs1 +Cc1ccc(Nc2nc(C)c3c(n2)CCCC3=O)cc1 +Cc1ccnc(NC(=O)c2cc(C3CC3)nc3c2c(C)nn3C)n1 +CCC(C)NC(=O)c1cc(=O)c2cc(C(C)C)cc(N)c2o1 +Cc1cc(C(=O)CSc2nncs2)c(C)[nH]1 +COc1cc(CNC(=O)Nc2ccc(-c3csnn3)cc2)ccn1 +CCOc1ccc(-c2csc(-c3nonc3N)n2)cc1 +COc1ccc2nc(CC(=O)c3cccc(Cl)c3)[nH]c(=O)c2c1 +CC(=O)NCC1(c2cccc(Cl)c2)CCOCC1 +Cc1ccc(NC(=O)N2CCCCC2C)c(OCC(=O)N(C)C)c1 +Cc1cc(C(=O)N2CCc3nc(NC(=O)C4CC4)sc3C2)no1 +CC(CC(O)c1ccco1)NC(=O)NCC1COc2ccccc2C1 +O=C(NC1CCCN(C(=O)c2cccs2)C1)c1cc(C2CC2)n[nH]1 +C=CCN(CC=C)C(=O)Cc1ccc(NC(C)=O)cc1 +O=C(NCC(F)(F)F)c1cc(-c2ccccc2Cl)on1 +O=S(=O)(c1c(F)cccc1F)N1CCN(c2ncccn2)CC1 +O=S(=O)(Oc1ccc2ccccc2c1)c1cn[nH]c1 +CC(=O)c1cccc(OC(=O)c2ccc(-c3nc(C)no3)cc2)c1 +CNC(=O)Cc1ccc(NC(=O)COc2ccccc2OC)cc1 +OCC(O)C1OC2OC3(CCCCC3)OC2C1O +CCNc1nc(-c2cccnc2)nc2sc(CC)cc12 +COc1ccncc1NC(=O)c1ccnc(OC2CCC2)c1 +CC(=O)NCCNC(=O)C1CCCN1S(=O)(=O)c1cccs1 +CCN(CC)C(=O)c1cnc(C2CCCCN2C(C)=O)nc1C +Cc1ccc(NC(=O)N2CCCC(C)C2CO)c(C)c1 +Clc1ccc(Cn2cc(NCc3cccc4cn[nH]c34)cn2)cc1 +CC(=O)Nc1ccc(Nc2ncnc(Nc3cccc(C)n3)c2N)cc1 +Cc1csc(NC(=O)c2ccc(-c3cc[nH]n3)cc2)n1 +Cc1ccccc1OC1CN(C(=O)c2cccc(O)c2)C1 +CSc1ccccc1C(=O)Nc1cc(C)nn1C +NC(=O)NCc1ccc(C(=O)NCCc2ccco2)cc1 +O=C(NCc1cccnc1)Nc1ccc2c(c1)OCO2 +CCc1ccc2occ(CC(=O)Nc3ccc(NC(C)=O)cc3)c2c1 +O=C(NCCNC(=O)N1CCC(CO)CC1)c1ccc(F)cc1 +COC(=O)Cn1ccn(-c2c(C)cccc2C)c(=O)c1=O +CCOC(=O)CCc1c(C)nc2c(C#N)cnn2c1C +COc1ccccc1-c1cc(C(=O)N(C)C2CC2)no1 +O=C(Nc1ccc(SC(F)F)cc1)c1ccnnc1 +CCOC(=O)c1ccoc1Cn1cnc2ccccc2c1=O +CC(NC(=O)c1ccccc1)C(=O)NCc1ccc(F)cc1 +Cc1nc2cc(-c3cn4cccc(N)c4n3)ccc2o1 +COc1cccc(Cn2ccnc2-c2ccc(NC(C)=O)cc2)c1 +CC(=O)NCCNC(=O)C(C)Sc1cc(Cl)ccc1Cl +Cn1cnc(CNC(=O)NCc2cccc(-c3ccccn3)c2)n1 +CC(C)n1cnnc1CN(C)C(=O)c1ccc(CCC(C)(C)O)cc1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)N1CCN(CCO)CC1 +CC(C)(C)OC(=O)N1CCC(O)(c2ccc(Cl)cc2)CC1 +COC(=O)C1=C(C)C(C(=O)NC2CCOc3ccccc32)=NC1C +CC(=O)Nc1cccc(NC(=O)Cn2nc(C)nc2C)c1 +COc1nc2sc(C(=O)NC3CC3)c(N)c2c(C)c1Cl +COCCCn1ccc2nc3ncnn3c(-c3ccccc3)c2c1=O +CCc1cc(OC(=O)CCC(=O)N2CCOCC2)ccc1Cl +CCCN(CC1CC1)C(=O)c1ccc(C(=O)OC)cc1 +COc1ccc(C2CN(S(=O)(=O)N(C)C)CC2NC(C)=O)cc1 +Cc1ccc(OC2CCN(C(=O)CCn3cncn3)CC2)cc1 +CCN(Cc1cccc(F)c1)C(=O)Nn1cnc2ccccc21 +C#CCOc1ccc(N(C)C(=O)c2ccc(-c3nc(C)no3)cc2)cc1 +O=C(Cc1ccc[nH]1)NC1CCCN(c2ccccc2)C1 +CC(C)(C)c1noc(CCC(=O)NCc2ccoc2)n1 +COc1ccc(C2CCCN2C(=O)C2CC=CCC2)cc1OC +Cc1ccc(C(=O)N2CCN3C(=O)C(CO)NC(=O)C3C2)cc1 +COc1cccc2cc(C(=O)NCCc3cc(C)no3)c(=O)oc12 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)NC(C)C1CCCO1 +O=C(CN1CCOC(c2ccccc2Cl)C1)NCc1cccnc1 +Cc1ccc(C(C)NC(=O)C(NC(N)=O)C(C)C)cc1F +Fc1cccc(Cl)c1Cn1nnc(-c2ccsc2)n1 +O=C(Nc1ccc(F)cc1)C(O)c1ccc(Cl)cc1 +CCOc1ccc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)cn1 +CN(CCC#N)c1ccc(S(C)(=O)=O)cc1N +CC(=O)Nc1cccc(C(=O)Nc2ccc(N)nc2C)c1 +Cc1cnn(C(C)C(C)NCC2=NS(=O)(=O)c3ccccc3N2)c1 +C#CCN1C(=O)C(Cc2ccccc2C)Oc2cc(N)ccc21 +COc1ccccc1NC(=O)c1cccc(N2CCCC2=O)c1 +COc1ncccc1CNC(=O)NC(C)C1CCCO1 +CN(C)c1cccc(C(=O)NCc2ccccc2)c1 +CCOC(=O)c1cc(N)c(N2CCCC2)c(Cl)c1 +ClC(Cl)(Cl)COCn1nnc2ccccc21 +Cn1ccc2cc(C(=O)NCc3c(F)cccc3F)ccc21 +c1ccc(CNCCc2nc(-c3ccccn3)cs2)nc1 +O=C(CNC(=O)c1cccs1)Nc1ccccc1 +COc1cccc(N2CCC(CNc3nnc(C)c(C)c3C#N)C2)c1 +CCCc1cc(=O)c2cccc(Br)c2[nH]1 +C=CCn1c(SC(C)C(=O)N(C)C)nc2sccc2c1=O +Cc1n[nH]c2c1C(c1cccc(Br)c1)CC(=O)N2 +CC(c1ccncn1)N(C)C(=O)CCCc1ccc(Cl)cc1 +O=S(=O)(c1cn[nH]c1)N1CCCC(Cc2cccnc2)C1 +c1cc(-c2ccc3c(c2)OCO3)nc(N2CCOCC2)n1 +Cc1ccc(-c2ccc(N3CCCC3)nn2)cc1S(N)(=O)=O +O=C(NC1CC1)c1c[nH]c2ccc(Br)cc12 +CS(=O)(=O)NCC(=O)Nc1ccc(CC#N)cc1 +CSc1ncccc1C(=O)Nc1cc(-c2ccccn2)no1 +Cc1cc(Oc2ncccn2)ccc1NC(=O)N1CC(C)CCC1C +CCCNC(=O)N1CCN(c2cccc(OC)c2)CC1 +O=c1ccccn1Cc1cccc(C(F)(F)F)c1 +Cc1csc2c(-c3ccc4c(c3)OCCO4)ncnc12 +Cn1cc(C(=O)Nc2ccc3c(c2)NC(=O)CS3)c(C(C)(C)C)n1 +Cc1ccc(-n2nnnc2SCC(=O)N2CCN(C)CC2)cc1 +CC(COc1ccc(F)cc1)NC(=O)N(C)Cc1ccco1 +Cc1cccc(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)c1 +Cc1cc(CO)nc(Cc2c(F)cccc2Cl)n1 +O=C(NCc1nc(-c2cccc(Cl)c2)no1)NC1CCCC1 +Cc1cc(C)c(NC(=O)CNC(=O)c2cccc(C)c2C)c(C)c1 +Cc1cc(C(=O)NC(C)C)c2cnn(Cc3cccs3)c2n1 +Brc1cc(CN2CCOCC2C2CC2)c2ncccc2c1 +O=C(NCc1nccs1)c1cc(F)ccc1-c1ccccc1 +O=C(CCNC(=O)c1cccs1)NCC1Cc2ccccc2O1 +O=C(CCNS(=O)(=O)c1cccnc1)OC1CCCCCC1 +COc1cncc(C(=O)Nc2cc(OC)ccc2OC)c1 +C=CCCCN(C)C(=O)c1cn(-c2ccc(C(F)(F)F)cn2)nn1 +CN(C)c1nc(NC(C)(C)C)nc(SCC#N)n1 +CC(C)N1C(=O)C2(CC(O)=Nc3c2cnn3C(C)C)c2ccccc21 +COC(=O)C1(NCc2cc(Cl)ccc2OC)CC1 +Cc1nc(-c2cccnc2SCC(=O)N(C)Cc2ccco2)no1 +CC1=C(C(=O)OC(C)C)C(c2ccncc2)NC(=O)N1C +CC(C)(CO)CNC(=O)C1CCC(=O)N(CC2CCCCC2)C1 +Cc1ccc(-c2ncco2)cc1NC(=O)N1CC2OCCN(C)C2C1 +Cc1cc(N)ccc1NC(=O)c1cc(Cl)ccc1F +Cc1ccc(C)c2c(C)c(C(=O)OCCN3CCCC3=O)oc12 +CSc1ccc(CNC(=O)NC(C)C(C)C)cc1 +O=C(Nc1ccn(Cc2ccccc2)n1)c1c(F)cccc1F +CCCCCOCc1nc(N)c2c(C)c(C)sc2n1 +CC(C)(C)NC(=O)CCSc1nnnn1-c1ccccc1 +Cc1ccc(C(=O)OC(C)C(=O)NCc2ccccc2)cn1 +CC(C)(C)c1cc(CN2CCN(c3ncnc4[nH]cnc34)CC2)n[nH]1 +CC(C)(NC(=O)CNS(C)(=O)=O)c1ccccc1 +CC1CN(C(=O)CCc2nc(-c3ccncc3)no2)CC(C)O1 +Cc1nc(-c2cccnc2)cc(N2CCc3ccccc3C2)n1 +COc1ccccc1CNC(=O)C(C)Oc1ccccc1C(N)=O +CN(Cc1cccnc1)C(=O)CN(C)S(=O)(=O)c1cccnc1 +Cc1ccccc1S(=O)(=O)Cc1ccc(C(=O)N2CCCCC2)o1 +COc1ccc(Cn2nnc(-c3ccccc3)n2)cc1 +CCSc1cc(C(=O)Nc2ccc3nc[nH]c(=O)c3c2)ccn1 +Cn1c(N)c(C(=O)CSc2nccn2C2CC2)c(=O)n(C)c1=O +O=C(CCn1ccccc1=O)NCc1cccs1 +CC(C)CCNS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +CC1CN(S(=O)(=O)NCc2cn(-c3ccccc3)nn2)CCO1 +COc1ccc(SCC(=O)Nc2cccc(C(C)=O)c2)cc1 +COCC(C)NC(=O)Nc1ccc2c(c1)CCC(=O)N2 +CCC(CC)N(CCO)c1ncnc2sccc12 +Cc1cc(Cl)ccc1OCCCC(=O)NCc1ccco1 +Cc1cc(C(=O)Nc2ccc(-c3nc4ccccc4o3)cc2)nn1C +CC(=O)Nc1cccc(C(=O)NCC(F)(F)F)c1 +CN(C)C(=O)C1(C)CN(Cc2ccc(F)c(F)c2)CCO1 +Cc1cccc(-c2noc(CN(C)C(=O)c3cc(C(C)C)n[nH]3)n2)c1 +Cc1nc(-c2nnc(NC(=O)c3ccnn3C)o2)cs1 +COc1ccccc1CC(C)(C)NS(=O)(=O)c1cnn(C)c1 +Cc1ccc(Br)c(NCC(=O)N(CCC#N)CCC#N)c1 +NC(=O)COc1ccccc1C(=O)NCCc1ccccn1 +COC(=O)C(NC(=O)c1ccc2c(c1)OCC(=O)N2)C(C)(C)C +O=S(=O)(c1cccs1)N1CCC(C(O)C(F)(F)F)CC1 +COC(=O)c1ccc(CNCc2nncn2C)o1 +Cc1nc(COc2ccc(CN3CCOCC3C3CC3)cc2)no1 +CC(=O)c1cccc(OC(C)C(=O)Nc2ccc3ccccc3n2)c1 +CSc1nc2nc(C)c3c(=O)n(CCCO)ccc3n2n1 +Cc1ccc(F)c(OCc2ccc(C(=O)N(C)C)cc2)c1 +CN(Cc1ccccn1)C(=O)NCc1cccc(Cl)c1 +CC(Oc1ccccc1)C(=O)C(C#N)c1ccccn1 +O=S(=O)(CCc1ccccn1)NCc1cnn(-c2ccccc2)c1 +O=C1CN(C(=O)CCCOc2cccc(Br)c2)CCN1 +Cc1cc(NC(=O)CCCc2c[nH]c3ccccc23)n(C)n1 +Cc1ccc2c(c1)c(=O)c(S(=O)(=O)c1ccc(F)cc1)cn2C +Nc1cccc(C(=O)CCNc2ccc(Cl)cc2)c1 +CCC1C(=O)NCCN1CC1=Cc2ccccc2OC1 +Cc1ccc(NC(=O)COC(=O)c2cccnc2)cc1C +CCC(=O)N1CCCC(c2nnc(-c3ccccc3F)s2)C1 +O=S(=O)(c1cccs1)N1CCC(n2cc(CO)nn2)CC1 +O=C(Nc1ccccn1)c1cccc(NC(=O)C2CC2c2ccco2)c1 +CC1CCc2c(C(=O)Nc3ccc(NC(N)=O)cc3)csc2C1 +CSc1nc2ccccc2n1CC(=O)N1CCOCC1 +CC(NC(=O)c1c[nH]c(=O)c(Cl)c1)C(=O)NC(C)(C)C +NC(=O)C1CCN(C(=O)c2[nH]nc(C3CC3)c2Br)C1 +COc1cc(OC)cc(C(=O)NCc2cccc(C#N)c2)c1 +COc1ccc(CN(C)CC(F)(F)F)cc1OC(F)F +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)Nc1ccccc1F +Cc1ccc(N(Cc2ccco2)C(=O)c2ccnnc2)cc1 +C=CCOC(C)C(=O)Nc1c(C)nn(C(C)C)c1C +Cc1ccoc1C(=O)N1CCNCC1C(=O)NCc1ccncc1 +CCOc1ccc(S(=O)(=O)N(CC)Cc2ccoc2)cn1 +CCc1nc(-c2cncnc2C2CCCN(c3cccnc3)C2)no1 +CCOC(=O)Nc1cc(-c2ccco2)nn1-c1nc(CC)cc(=O)[nH]1 +CCc1nc2n(n1)CCCC2NC(=O)c1sc(CC(C)C)nc1C +CCC(OC)C(=O)Nc1cccc(N2CCOCC2)c1 +CC(NC(=O)CCNC(=O)c1ccccc1F)C(N)=O +Cc1cc(C(F)(F)C(F)(F)F)n2ncc(Cl)c2n1 +O=C(Nc1ccccc1)N1CC2CC(C1)c1cccc(=O)n1C2 +O=C(Nc1c[nH]ccc1=O)c1ccc(SCc2ccccc2)cc1 +COc1ccc(F)cc1C(C#N)CC(=O)N1CCC(C)CC1 +O=C(NC1CCCCC1)N1CC2OCCN(C(=O)c3ccco3)C2C1 +C=CCOc1ccc(C(=O)N2CC(C)CC(C)C2)cc1 +CCOc1ccc2nc(NC(=O)c3ccc4[nH]cnc4c3)sc2c1 +CN1C(=O)c2cc(NC(=O)c3ccccn3)ccc2N2CCN=C12 +CC(=O)NCCNC(=O)N1CCC(c2nc3ccccc3s2)CC1 +Cc1cnn(C(C)C(C)NCc2ccc(C#N)cc2F)c1 +Cc1ccc(C(O)CCC(=O)N2CCC(C)CC2)cc1N +Cc1cccc(NC(=O)CSc2nc(CC(C)C)n[nH]2)c1 +O=C(Cc1cn2ccccc2n1)NCC1(c2ccccc2)CCC1 +CC(=O)Nc1ccccc1C(=O)OCc1ccc2c(c1)OCO2 +Cc1ccsc1CN1CCC2(CC(NC(=O)N(C)C)CCO2)C1 +CCN(CC)S(=O)(=O)c1cc(C(=O)NC(C)C)ccc1OC +CC(=O)Oc1cccc(C(=O)c2cc(F)c(F)c(F)c2)c1 +CC(C)(C)N(Cc1ccccn1)C(=O)c1cc2ccccc2o1 +CCn1c(SCCOC)nnc1-c1ccccc1 +O=C(NCc1nnc2ccccn12)c1cc(Cl)ccc1O +CN(C)C(=O)COc1cccc(NCC(=O)N2CCCCC2)c1 +CN(Cc1cccc(-c2cccnc2)c1)Cc1nccs1 +CCn1cnnc1CNC(=O)NCC(O)c1ccccc1Cl +COC(=O)c1ccc(Nc2ccc(N)c(C)n2)cc1 +CC1Oc2ccccc2N(CCC(=O)N(CCO)C2CC2)C1=O +Cc1nn(-c2ccccc2)c(-n2cccc2)c1C(=O)N(C)C +CCN(CC)C(=O)CCC(=O)Nc1ccc(Cl)cc1 +CNC(=O)c1cccc(NCCn2nc3ccccn3c2=O)c1C +CC(C)C(=O)N1CCC2CN(CC(=O)N(C)C)S(=O)(=O)C2CC1 +NC(=O)C1CN(C(=O)NCc2cccc(F)c2)CCO1 +CC(C)Cc1ncc(CN2CCOC(c3nccs3)C2)s1 +N#Cc1c(NC(=O)c2ccno2)sc2c1CCCCC2 +c1ccc(-n2cc(CSc3nnc4[nH]c5ccccc5n34)cn2)cc1 +CC(Cc1ccco1)NC(=O)NCc1ccc(S(C)(=O)=O)cc1 +CCCNC(=O)C1CCN(c2cc(Oc3ccccc3)ncn2)CC1 +Cc1nc2c(c(C)c1CNC(=O)c1cc3ccccc3[nH]1)c(=O)[nH]n2C +COc1ccccc1CSc1nnc(C(C)(C)C)n1N +COCc1nc(NCc2ccc(OC)cc2)c(N)c(OC)n1 +COCC(=O)NC1CCCCC1NC(=O)OC(C)(C)C +Cc1cccc(OC(F)F)c1NC(=O)NCc1cccc(C(N)=O)c1 +Cc1cnc(CCNC(=O)Cc2ccccc2OC(C)C)s1 +CN(C)C(=O)CN(C)C(=O)c1ccccc1S(C)(=O)=O +Cc1nc(N2CCC3(CCCN(CCO)C3=O)C2)c2ccsc2n1 +CNc1snc(C)c1C(=O)OCc1cccc(C(C)=O)c1 +COc1ccsc1C(=O)NCc1cc(C(C)C)no1 +O=C(c1ccco1)N1CCN(c2c(F)c(F)c(F)c(F)c2F)CC1 +Cc1cc(NC(=O)Nc2cccc(NC(=O)c3cccs3)c2)no1 +Cc1c(-c2ccccc2)oc2c(C(=O)N3CCCC3)cccc2c1=O +NC(=O)c1ccc(C(=O)Nc2ccc(F)cc2)cc1 +O=C(Nc1nnc(-c2cccs2)o1)NC1CCCC1 +CC1CC(C)CN(C(C(=O)NC2CC2)c2ccccc2)C1 +Cc1n[nH]c(C)c1NC(=O)CSc1ncccc1Br +CC(C)(C)OC(=O)N1CCC(CNc2c(N)cccc2F)CC1 +O=C(NC1(c2ncon2)CCOCC1)c1cc2ccccn2c1 +COC(=O)Cc1csc(NC(=O)c2c(C)oc(C)c2C)n1 +CC(=O)Nc1ccc(C(=O)NC(C)c2ccccc2C)cc1 +CCCCCCn1nnc(CO)c1-c1cccs1 +CC(NC(=O)CCN1CCOC1=O)c1ccc(Br)cc1 +Cn1cc(NC(=O)Cn2nnc(-c3ccccc3)n2)cn1 +Cc1noc(CCC(=O)OC2CCCc3nc(C)sc32)n1 +Cc1nn(-c2ccc(Cl)cc2)c(C)c1C(=O)NCC(C)C +CC(=O)NC(C)C(=O)N(C)Cc1ccc(OC(F)F)cc1 +COc1cc(C#N)ccc1OC(=O)Cn1nnc(-c2ccccc2)n1 +CCC(C)NC(=O)c1ccc(N)c(OCc2ccccc2)c1 +CC(C)CCCC(C)NC(=O)c1ccc(-n2cncn2)nc1 +CCCn1nc(C)c(CNc2ccn(-c3ncccc3Cl)n2)c1C 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+O=C(Cc1ccc(OC(F)F)cc1)N1CCCC(O)C1 +O=C(NCc1ccccn1)c1nc(-c2ccncc2)cs1 +COC(=O)c1cc(S(=O)(=O)Nc2ccccc2OC)cn1C +C=CCN1CCCC2(CCCN2C(=O)OC(C)(C)C)C1=O +O=C1Cc2cc(C(O)c3ccc(F)cc3)cc(F)c2N1 +Cc1ncsc1CCSc1n[nH]c(=O)n1-c1ccccc1 +CNC(=O)NCC(=O)NCc1ccccc1OC1CCC1 +Cc1nc(C)c(CCC(=O)NC(C)c2cc3ccccc3o2)c(=O)[nH]1 +COc1ccc(OC)c(CN(C)c2nc3c(cnn3C)c(=O)[nH]2)c1 +C#CCCOC(=O)c1cccc(NC(=O)NC(C)C)c1 +CSc1ccc(C)c(C(=O)Nc2cccnc2)c1 +Cc1cc(C)n(C2CCN(c3ccc(-c4nc(C)no4)cn3)C2)n1 +CN(CCc1nc2ccccc2c(=O)[nH]1)Cc1ccccc1 +Cc1ccc(C(=O)NC(C#N)c2ccncc2)cc1C +O=C(c1c2c(nc3ccccc13)CCC2)N1CCCC1 +COCCCNC(=O)CN1C(=O)C(C)(C)c2cc(C)ccc21 +CC(O)c1nc2cc(N)ccc2n1-c1ncccc1C#N +NC(=O)c1cccc(NC(=O)c2ccccc2Br)c1 +Cc1cccnc1NC(=O)CC(c1cccc(F)c1)n1cccc1 +Cn1cc(C2(C)CN(c3noc(-c4ccccc4)n3)CCO2)cn1 +CC(=O)Nc1ccc2nc(NC(=O)Cc3ccc(C)cc3)sc2c1 +C=CCNC(=O)N(C)C1CCN(c2ccc(F)cc2)CC1 +COc1ccccc1CC(=O)Nc1ccccc1C(N)=O +Cc1nc(C)c(C(=O)N(C)CCOc2cccc(Cl)c2)s1 +CCCCn1nc(C(=O)N2CCCN(C(=O)CC)CC2)ccc1=O +CN1CC(=O)Nc2cc(C(=O)NCC3CCC3)ccc21 +Cc1occc1C(=O)N1CCCC1CC(=O)c1ccccc1 +CC(=O)NC1CCCN(C(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)C1 +CN(CCc1ccccc1)C(=O)c1ccc(N2CCOCC2)c(F)c1 +CCCC(C)(C)NC(=O)Cn1cccc(C(F)(F)F)c1=O +O=c1c(Br)c(N2CCOCC2)cnn1-c1ccccc1 +CC(C)Oc1ccc(C(=O)Nc2cnn(-c3ccccc3F)c2)cn1 +Cc1noc(C)c1CC(=O)Oc1ccc(C#N)cc1Cl +CC1CCCCC1NC(=O)COCc1nc2ccccc2s1 +CN(C)S(=O)(=O)c1csc(C(=O)Nc2ccccc2)c1 +CN(C)C(=O)C(NC(=O)c1c[nH]nn1)c1ccccc1 +Cc1csc(CN(CC2CC2)C(C)c2ccccc2)n1 +O=C(Cn1c(=O)oc2ccccc21)NCc1ccccc1CO +CCC(C)(C)NS(=O)(=O)c1ccccc1OC +COc1ccc(Cl)cc1NC(=O)c1cc2c([nH]c1=O)CCCC2=O +CN(CC(=O)N1CCCC1)C(=O)c1ccc(N)cc1 +Cc1nn(C)c(C)c1-c1ccc(=O)n(C(C)C(=O)N2CCCCC2)n1 +COC(=O)CNC(=O)c1ccccc1Nc1ccc(OC)cc1 +CCCc1nnc(NC(=O)NC(C)Cc2c(C)nn(C)c2C)s1 +CC(C)Oc1cccc(CC(=O)NCC(C)(C)c2ccncc2)c1 +CCOC(=O)N(C)c1ccc(NC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +Cc1ccccc1-c1onc(C)c1C(=O)NCc1ccccn1 +Cc1cc(C)n(CCCNC(=O)c2ccc3ncsc3c2)n1 +Cc1cc(C(=O)OC(C)c2ccc3c(c2)OCO3)[nH]n1 +COc1ccc(-c2cc(C(=O)Nc3cccc(F)c3)n[nH]2)c(OC)c1 +c1cc2ccc(CNc3ccc4cn[nH]c4c3)cc2[nH]1 +COc1ccc(NC(C)=O)cc1NCc1c(C)nn(CCO)c1C +CC(C)(CNC(=O)c1ccc(-c2ccccc2)cc1)C(N)=O +CC(C)OCc1ccc(C(=O)N(C)CC(N)=O)cc1 +CC(=O)NC(C(=O)Nc1cccc(-n2cnnn2)c1)C(C)C +CC(=O)N(CCc1ccccc1)CC(=O)N1CCCC1CC(C)C +O=C(COc1ccc(Cl)cc1Cl)NCc1cccnc1 +O=C(CCn1ncc2ccccc21)NCc1cccc(Cl)c1 +Cc1cc(C(=O)NCC2CCCO2)c2nc3n(c2n1)CCCCC3 +Cc1nnc(CSc2nnc(-c3ccc(Cl)cc3)n2N)o1 +Cn1ncc(C(=O)NCCCOCc2ccco2)c1N +CCCC1CN(C(=O)c2cnc(OCC)c(Cl)c2)CCO1 +CC(C)Oc1ccc(CNC(=O)c2ccc(OC(F)F)cc2)cn1 +CCN(CC)S(=O)(=O)c1ccc(C(=O)Nn2cnnc2)cc1 +Cc1nn(-c2ccccc2)nc1C(=O)NCCc1ccccc1 +NC(=O)CN1c2ccc(Cl)cc2-c2ccccc2S1(=O)=O +CC(=O)Nc1cccc(NC(=O)CCC(=O)c2cc(C)sc2C)c1 +Cc1c(Cn2cc(-c3cncnc3)nn2)oc2ccccc12 +N#Cc1cccnc1NCCOC(=O)c1cccc(-c2ccoc2)c1 +COC(=O)c1ccc(Cn2c(=O)c3cccn3c3cccnc32)o1 +COc1cc(OC)cc(C(=O)N2CCN(Cc3ccccc3)CC2)c1 +CCOc1ccc(-c2nn3c(-c4ccncc4)nnc3s2)cc1 +O=C(NCCN1CCOCC1)c1cc2ccccc2[nH]1 +CC(=O)c1c(C)nc(C)nc1SCC(=O)C(C)(C)C +COc1ccc(C(=O)NCCCc2nc3ccccc3[nH]2)cn1 +CN(c1ccccn1)S(=O)(=O)c1cccc(Cl)c1F +NC(=O)c1nnn(-c2ccc(NC(=O)c3ccco3)cc2)n1 +O=C(Nc1ccc(F)cn1)c1cncc(Br)c1 +CN(C)C(=O)c1ccc(C(=O)NCc2cccc(C(N)=O)c2)cc1 +O=C(NCc1ccccc1-c1cccnc1)c1cc2cccnn2c1 +O=C(NCc1ccncc1)c1cc(-c2cc(Cl)ccc2O)n[nH]1 +COc1ccnc(N2CCc3[nH]nc(-c4ccc(F)cc4F)c3C2)n1 +COc1ccc(OC)c(NC(=O)c2n[nH]c3c2CCCC3)c1 +Cc1cc(NCc2c(Cl)cccc2Cl)no1 +Cc1ccc(NC(=O)N(C)CCO)cc1C(F)(F)F +COc1ccc(NC(=O)C2CCCCCC2)cc1N +CC(C)(C)OC(=O)N1CCC(C#N)(COCc2ccccc2)CC1 +NC(=O)c1ccc(NC(=O)C#Cc2ccccc2)cc1 +Cc1ccc(C(=O)NCC(=O)Nc2ccc(F)c(F)c2)cc1C +CCN(CC)C(=O)CCC(=O)NC1CCN(c2ccccc2)C1=O +CN(C)C(=O)c1cccc(C(=O)N2CCc3cc(F)ccc3C2)c1 +CC(Sc1ccccc1)C(=O)N1CCN(C)CC1 +CC1CCCC(NC(=O)CN2CCCS2(=O)=O)C1 +COc1ccc(NC(=O)c2[nH]nc3c2CCCC3)cn1 +N#Cc1cccnc1S(=O)(=O)Cc1ccccc1 +Cn1ccnc(NC(=O)c2coc3ccccc23)c1=O +CCOc1c(CNn2nnnc2N)cccc1OC +Cc1ccc(S(=O)(=O)NCc2cccnc2)c(C)c1 +CCC(Oc1ccccc1C(C)C)C(=O)NC1(C#N)CCOCC1 +Cc1n[nH]cc1CN1CCCC1Cc1cccc(F)c1 +CNC(=O)CCOC(=O)c1cccc(-n2ccc(C(F)(F)F)n2)c1 +O=C1CCCCN1CCOc1ccc(Br)cc1 +Cc1occc1C(=O)N1C2CCC1CN(Cc1cccnc1)C2 +CCCc1nc(C)c(CNC(=O)c2cnc(C3CC3)[nH]c2=O)s1 +CC(Oc1ccccc1)C(=O)NC(C)c1ccc(-n2cncn2)cc1 +Cc1cc(NC(=O)Cc2noc(C(=O)NC3CCCC3)n2)no1 +CCCNC(=O)c1oc2c(c1C)C(O)CC(C)(C)C2 +CCC(NC(=O)N1CCN(C(=O)c2ccco2)CC1)c1ccncc1 +Cc1n[nH]c2ncc(NC(=O)C3CCC(F)(F)CC3)cc12 +CCOC(=O)CN(CC)C(=O)c1ccc(OC)cc1 +CN(C(=O)Cc1cn2ccsc2n1)C1CCc2ccccc2C1 +Cn1c(=O)ccn(CC(=O)Oc2cccc3ccccc23)c1=O +Clc1cnn(Cc2cccc(Br)c2)c1 +Cc1[nH]ncc1CCCNC(=O)C(C)Oc1ccc(F)c(F)c1 +CCN(CC)C(=O)CCC(=O)N=c1[nH]c2ccccc2[nH]1 +COc1c(Cl)cc(C(=O)N2CCC(C)CC2)cc1Cl +O=C(NCC(F)(F)F)c1cc(-c2ccccc2O)n[nH]1 +Nc1ccc(Sc2ncn[nH]2)nc1OCC1CC1 +Cn1ccc(NC(=O)Cc2ccc(F)c(Br)c2)n1 +COc1ccc(Cc2nnc3n2N=C(C)C(C)S3)cc1 +Cn1cc(NC(=O)NCC2(N3CCOCC3)CCCCC2)cn1 +CC(=O)C1C(c2ccncc2)NC(=O)NC1(O)C(F)(F)F +CC(CNC(=O)CCn1ccccc1=O)N(C)c1ccccc1 +O=C(NC1CCCCC1)C1CCN(c2ccc3nnnn3n2)CC1 +O=C(c1cccc(CNc2ccc(Cl)cn2)c1)N1CCCC1 +CC(C)(C)OC(=O)NCCCC(=O)Nc1ccc(F)cc1F +COC(=O)c1sc(COc2cccc(N(C)C)c2)nc1C +CCC(C)Sc1nnc(C2COc3ccccc3O2)n1C +CCCCn1c(CN(C)C(=O)c2ccccn2)nc2ccccc21 +Cc1cc(C)n(-c2ccc(CSc3nncs3)cc2)n1 +Nc1c[nH]c(-c2cc3cccc(Br)c3[nH]2)c1 +CCOC(=O)CNC(=O)NCc1cccc(OC)c1 +COC(=O)c1ccc(NCc2ccnc(C)n2)cc1 +O=C(Nc1ccn(Cc2ccncc2)n1)c1cccc(C(F)(F)F)c1 +COc1ccccc1OC(=O)Nc1ccc(Cl)cc1 +CC(C)(C)C1CCC(O)C(CN2CCOCC2)C1 +COc1cc(C2(O)CCCCC2C)cc(OC)c1OC +CCN(C(=O)CNS(=O)(=O)c1cn(C)cn1)c1ccccc1 +CC(CC#N)N(C)C(=O)Nc1ccc(Cl)c(Cl)c1 +CCC1CCCN(C(=O)NCc2ccccc2-n2ccnc2)C1 +CC(C)NC(=O)Cn1cccc2cc(-c3ccc(F)cc3)nc1-2 +CC(C)(C)OC(=O)NCCC(=O)Nc1ccc(O)cc1 +C=CCOC(=O)c1ccc(N2CCN(c3ccccc3)CC2)nc1 +Cc1ccccc1NC(=O)c1ccc(C(=O)Nc2ccccc2C)nc1 +Nc1cnc(Cc2ccc3c(c2)NC(=O)CS3)nc1 +CCCC(=O)NCc1csc(-c2ccc(OC)cc2)n1 +NC(=O)Cn1cnc2c(-c3ccc(Cl)cc3)csc2c1=O +COc1cc2c(cc1C)CCNC2c1ccc(F)nc1 +CN(Cc1cnn(-c2ccccc2)c1)S(=O)(=O)N1CCCCCC1 +Cc1nc(Nc2ccccn2)cc(C2CCCN(c3ncccn3)C2)n1 +COc1cccc(C(=O)Nc2cccc(CO)c2)c1 +N#CCCCSc1ncnc2sc3c(c12)CCCC3 +CCC(=O)c1ccc2c(c1)N(CCCO)C(=O)C(C)(C)O2 +CC(C)(C)C(=O)N1CCN(c2ncnc3[nH]cnc23)CC1 +CCCN(C)C(=O)Nc1ccc(S(C)(=O)=O)nc1 +CCCCC(CC)CNC(=O)c1ccncc1F +COc1ccc(CNC(=O)N2CC(C)c3ccccc32)cn1 +CCn1nc(C)c(C(=O)NCc2c(OC)ccc3ccccc23)c1C +O=C(NC1CCN(C(=O)Nc2ccccn2)CC1)C1CCCCC1 +O=C(CCc1nc(-c2ccco2)no1)N1CCCC1Cn1cccn1 +CC(=O)c1ccc(NS(=O)(=O)c2ccc(Cl)cc2F)cc1 +COc1ccccc1S(=O)(=O)Cc1ccccn1 +Cc1cc(C)c(NC(=O)CCCSc2nc(C)cs2)c(C)c1 +O=S1(=O)N=C(NCc2ccc3c(c2)OCCO3)c2ccccc21 +CC(CC#N)N(C)Cc1ccccc1C(F)(F)F +COC(=O)c1sccc1NC(=O)N1CCc2ccccc21 +Cc1ccc(N2CCC3(CC2)COCCN3C)nn1 +CCCCOc1cc(C(=O)NC(C)CC)ccc1N +O=C(CSc1ncn[nH]1)NC1CCc2cc(Cl)ccc21 +Cc1cc(C)n(CC(C)CNC(=O)Nc2ccc(Cl)cc2)n1 +Cc1cccc(C)c1NC(=O)CS(=O)(=O)c1ccccc1F +Cc1cc(C)c(C(=O)NCCSc2ccc(Cl)cc2)c(=O)[nH]1 +CC(NC(=O)Nc1ccc(SC(C)(C)C)cc1)c1nncn1C +O=C(NCc1nnc(-c2ccccc2)s1)NC1C=CCCC1 +Nc1cc(C(F)(F)F)n(-c2ccc(F)c(F)c2)n1 +O=C(CCCc1nc(-c2ccccc2)no1)NC1CCCCNC1=O +COc1ccccc1-n1cnnc1SCC(=O)c1cnn(C)c1 +CC(C)c1ncc(Cl)c(C(=O)NC2CCC2)n1 +COc1ccnc(NC(=O)Cc2ccc(C)nc2)c1 +CCN(CC(=O)Nc1ccccc1OC)C(=O)c1cnn(CC)c1 +CCOC(=O)C(Cc1nccs1)=C(N)C(F)(F)F +CCc1nc(C2CCCN(C(=O)c3ccc4[nH]cnc4c3)C2)no1 +Cn1ccnc1C(NC(=O)N1CCC(CO)CC1)c1cccc(F)c1 +O=C(NCCc1csc(-c2ccncc2)n1)c1cccc(Cl)c1 +Cc1cc(NC(=O)C2CN(C(=O)c3c[nH]c4ccccc34)C2)sn1 +CCCNC(=O)CNC(=O)Nc1cc(C(=O)NC2CC2)ccc1C +CC(C)CC(C)Nc1nc(C(F)(F)F)cc(=O)[nH]1 +COc1ccccc1CNC(=O)c1nc(-c2c[nH]c3ccccc23)no1 +COc1ccccc1OCC(=O)N(C1CC1)C(C)c1cccnc1 +COC1C(O)C(CO)OC1N1CN=C2C(=O)N=CN=C21 +COCCn1cc(NC(=O)c2cccc(C(=O)OC)c2)cn1 +O=C(NCCOCC1CCCO1)N1CCc2cc(F)ccc2C1 +CC(=O)NC(C)C(=O)Nc1ncc(Cc2ccc(F)cc2)s1 +Cc1cc(C(=O)Nc2n[nH]c(-c3ccc(C(C)(C)C)cc3)n2)no1 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NCC(C)C#N)CC2)cc1 +Cc1nn(C)c(C)c1NC(=O)c1ccc(Cl)cc1F +Cc1cc(C(=O)COc2cnc(-c3ccccc3)nc2)c(C)n1C1CC1 +CC(C)(C)c1ccc(S(=O)(=O)NCc2ccccn2)cc1 +CCN(C)c1cc(N2CCOC(c3ccc(F)cc3)C2)ncn1 +Cc1ccc(S(=O)(=O)NCC(=O)NCC(N)=O)cc1C +CC(NC(=O)c1ccc(Cl)cc1)C(=O)NC(C)C(C)C +COCCOCC(=O)N1CCc2sccc2C1c1ccccc1 +Cc1ccc(CN(C)C(=O)COc2ccccc2Cl)o1 +O=C(COc1ccc(F)cc1)N(Cc1ccc2cc[nH]c2c1)C1CC1 +Nc1cnn(CCCOc2ccc(F)c(F)c2)c1 +CCN(CCO)C(=O)NCC(c1cccc(C)c1)N1CCOCC1 +CCN1CC(C(=O)NCCCn2cc(C)cn2)CC1=O +O=C(Cc1cc(-c2ccc(F)cc2)on1)Nc1ccncc1 +CNC(=O)C1Cc2ccccc2N1C(=O)c1c(F)cccc1Cl +COc1cccc(C(O)CNc2ccccc2OC)c1 +CCCNc1nnc(-c2sc(CCOC)nc2C)s1 +Nc1cc(Cl)ccc1S(=O)(=O)NCC1COCCO1 +O=C(NCc1ccncc1)c1cc2ccccc2nc1N1CCCC1 +Cc1ccc(Cn2nccc2NC(=O)c2ccc(C#N)cc2)o1 +COc1cc(C)ccc1NC(=O)COc1ccccc1F +CC(NC(=O)Nc1nnc(C2CCCCC2)s1)c1cccnc1 +CNC(=O)c1ccc(=O)n(CC(=O)c2ccc(C)s2)c1 +CCC(C)NC(=O)CCC(C#N)c1ccccc1Cl +Cc1nn(-c2ccccc2)c(C)c1NC(=O)CNc1ccccc1 +COC(=O)c1ccc(F)c(NCc2ccncn2)c1 +Cc1nnc(SCC(=O)c2ccccc2N)s1 +CCNC(=O)NC1CCN(c2cc(C)cc(C)c2)C1=O +CC(C)CCNC(=O)Nc1cnn(-c2ccccc2)c1 +CC1CC(=O)N(C)c2cc(F)cc(Br)c2O1 +COC(=O)c1ccoc1COc1cc(OC)ccc1C(N)=O +O=C1Nc2ccc(Br)cc2C12OCCO2 +CCN1C(=O)C(NC(C)=O)c2cccc(C(F)(F)F)c21 +CCc1cn[nH]c1C1CCN(C(=O)C(C)n2cc(C)cn2)CC1 +Cc1cc(C2CCCN2Cc2nc3ccccc3o2)on1 +COc1ccnc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)c1 +CCCCN(CC(N)=O)c1nnc(C)c(C)c1C#N +COC12C=CC(CC1)c1c(OC(C)=O)ccc(OC(C)=O)c12 +CCN1C(=O)c2ccc(C(=O)Nc3ccccc3C)cc2S1(=O)=O +O=C(COc1cc(Cl)ccc1Cl)C1=NC=CC1 +Cc1c(C(=O)NC2CCCCNC2=O)cnn1-c1ccc(Cl)cc1 +Cc1nn(C)c(C)c1CCC(=O)NCC1CCOc2ccccc2C1 +NC(=O)c1ccc(NC(=O)CCc2ccccc2)c(Br)c1 +NC(=O)c1cccc(CNC(=O)Nc2ccccc2-n2cccn2)c1 +Cn1cc(Br)cc1C(=O)NCC(O)Cc1ccccc1 +Cc1cccc(-n2nnnc2SCCn2c(C)csc2=O)c1 +CC(C)NC(=O)C1CNCc2cc(C(C)(C)C)ccc21 +Cc1nc2ccccc2c(=O)n1CSc1nnnn1C +CCc1ccc(NC(=O)C(N)c2ccccc2)cc1 +Cc1cccc(CCC(=O)N(C)Cc2cc(C)on2)c1 +CC(C)CCOCCNC(=O)c1ccc[nH]c1=O +CCC1CCC(NC(=O)NCc2ccco2)CC1 +Cc1ccc(-n2ccc3c(c(C)nc4nc(C)nn43)c2=O)c(C)c1 +CC(C)n1cccc1C(=O)Nc1cncnc1N1CCCC1 +Cc1n[nH]c(N2CCN(c3nc(=O)c(C)n[nH]3)CC2)nc1=O +O=C(CCC(=O)N1CCCS1(=O)=O)c1cccs1 +Cc1ccccc1C(C)NC(=O)c1nc(C)n(-c2ccc(F)cc2)n1 +CN(C(=O)c1ccc(-c2ccco2)[nH]c1=O)C1CCc2ccccc21 +Cc1noc(CCC(=O)NC(C)c2ccccc2C)n1 +CN(C)C(=O)c1ccc(C(=O)NCCc2ccccc2)cc1 +Cc1ccc(C)c(C(=O)NCC(O)c2ccsc2)c1 +CCCN(C(=O)CCC(=O)OC)c1cccc2ccccc12 +N#Cc1ccc(OCCN2CCCCC2C2OCCO2)cc1 +O=C(CCC(=O)c1ccc(F)c(F)c1)NCc1cccs1 +CCN(C(=O)C1CCCN(C(=O)Cc2ccccc2)C1)C1CCC1 +CS(=O)(=O)N(CCc1ccccc1)CC(=O)N1CCOCC1 +CC1CCN(S(=O)(=O)NCc2cccnc2)CC1 +Cc1cc(C)n(S(=O)(=O)c2cccc(S(C)(=O)=O)c2)n1 +Cc1nc(CNC(=O)C2CC2c2ccccc2Cl)c(C)s1 +CCOc1cc(C)c(Cl)cc1S(=O)(=O)NCC(C)O +Cc1ccccc1OC1CN(Cc2ccc(-c3cc[nH]n3)o2)C1 +CC(C)CC(=O)NCC(O)c1ccc(CC(C)C)cc1 +O=C(CCc1ccsc1)NCc1ccccc1Cl +Cc1oc2ccn(Cc3ccc(F)cc3)c(=O)c2c1C(=O)NC(C)C +O=S(=O)(Cc1noc(C2CC2)n1)c1ncccc1Br +COc1cc2ccccc2cc1C(=O)OCC(=O)NCC1CCCO1 +O=C(NCCc1nc(-c2ccc(Cl)cc2)no1)NCC(F)(F)F +O=C(CCc1ccccc1Cl)NCc1ccoc1 +O=C(CN1CCN(c2ccccc2)C1=O)NCc1ccccc1F +Cc1csc2nc(Cc3nc(N)nc(N(C)C)n3)[nH]c(=O)c12 +O=C(COC(=O)C1CCCCC1)NC1CCCc2ccccc21 +Cc1cccc(C(=O)Nc2nnc(-c3ccsc3)o2)c1 +Cc1ccc(C2CCCN2C(=O)c2nn(C)cc2Cl)cc1 +Cc1ccccc1-c1nc(C)c(CNC(=O)c2ccno2)s1 +O=C(Cc1csc(-c2ccccn2)n1)N1CCOC2CCCC21 +CC(C)C(C)(C#N)NC(=O)CN1CCc2ccccc2C1 +Cc1nc2ccccn2c(=O)c1NC(=O)C1CCCC1 +COc1ccc(C(=O)n2c3ccccc3c(=O)c3ccccc32)cc1 +Cc1nc(NC(=O)c2cn(C)c3ccccc23)sc1C +C#Cc1cccc(NC(=O)NC2CCN(C(=O)c3cnccn3)CC2)c1 +Cc1nnsc1C(=O)N(Cc1ccoc1)Cc1cccs1 +COc1ccc(C)cc1-n1nnnc1SCC(=O)N(C)C +COC(=O)CNc1cc(F)ccc1OCC(F)(F)F +Cc1ccc(C(C)NS(=O)(=O)c2cn[nH]c2)cc1 +O=C(NCc1ccco1)c1cc2c(F)cccc2s1 +O=C(Cc1cccs1)NCc1noc(CCc2ccccc2)n1 +CCc1sc(C(=O)N2CCOC(c3noc(C)n3)C2)cc1C +COCCN(C)C(=O)Nc1cccc(NC(=O)OC)c1 +CNC(=O)c1ccc(Cl)c(NC(=O)CSc2ccccc2)c1 +O=C(Nc1ccc(F)cc1F)c1ccc(-n2ccnc2)nc1 +CC1CCCN(C(=O)CNc2cccc(OCC(=O)N(C)C)c2)C1 +CCc1onc(C)c1NC(=O)CCCOc1ccc(Cl)cc1 +CC1CCC(N(C)C(=O)CN2CCOC(C(N)=O)C2)CC1 +CS(=O)(=O)c1ccc(NCc2ccccc2Br)cc1 +CCn1cnnc1CNC(=O)Nc1ccc(C(=O)OC)cc1 +CC(=O)N1CCC(C(=O)Nc2cccc(NC(N)=O)c2)CC1 +O=C(Cn1c(=O)oc2cc(Cl)ccc21)NCc1ccc(F)cc1 +COc1ccc(NC(=O)c2ccc(Cn3ccnc3)cc2)cn1 +CC(C)c1nnc2n1CCN(Cc1cccc3nccnc13)CC2 +COc1cc(N)c(C(=O)N2CCC(C)CC2)cc1OC +Cc1cnc2n(c1=O)CC(C(=O)NCCN1CCOCC1)CS2 +CCCNC(=O)c1nn(CC)cc1NC(=O)c1ccc(C)cc1 +Cc1c(N)cccc1NC(=O)Cn1cnc2ccccc21 +O=C(C1CCOCC1)N(CCO)C1CCCCC1 +c1ccc2c(c1)CC2CNc1nc2ccccc2o1 +O=C(NCc1cc[nH]n1)C1(c2cccc(Cl)c2)CC1 +CS(=O)(=O)c1ccc(F)c(NC(=O)C2(c3ccccc3)CC2)c1 +O=C(Nc1ccccn1)c1nnn(-c2cccc(F)c2)c1C1CC1 +Cc1ccc(C(C)C)cc1S(=O)(=O)N1CCC(C(N)=O)CC1 +CC(=O)c1ccc(N2CCN(C(=O)NC(C)C)CC2)c(F)c1 +O=C1CCN(C(=O)c2cc(-c3ccccc3)on2)C2CCCCC12 +CN(c1cc(F)ccc1F)S(=O)(=O)c1ccc2ncccc2c1 +COc1ccc(C(=O)NCC(=O)NCc2ccc(C)s2)cc1OC +Cc1cc(NC(=O)COc2ccc(F)cc2)n(CCC#N)n1 +CC(C)(C)C1CCN(S(=O)(=O)NCCNC(=O)C2CC2)CC1 +O=S(=O)(c1ccc2c(c1)OCCO2)N1CCC(n2cccn2)CC1 +CC(C)NC(=O)c1ccc(Cl)c(S(=O)(=O)N2CCCCC2)c1 +Cc1cc(-c2nnc3sc(C4CCC4)nn23)n(C)n1 +Nc1ccc(-n2cc(-c3ccc4c(c3)OCO4)nn2)c(Cl)c1 +CC1CCN(C(=O)CN2c3cccc4cccc(c34)S2(=O)=O)CC1 +Cc1n[nH]c(C)c1C(C)CC(=O)N(C)CCNC(=O)C(C)C +Cn1ncc2c1CCCC2NC(=O)NCc1ccco1 +CC1CCCCC1N(C)C(=O)c1cncc(Br)c1 +Cc1csc(NC(=O)Cc2cc(-c3ccc(F)cc3)on2)n1 +CC(=O)c1ccc(S(=O)(=O)NCCNC(=O)C2CC2)cc1 +O=C(Nc1cccnc1)Nc1ccc(OCc2ccccn2)c(F)c1 +Fc1cc2c(c(CN3CCCC(C(F)(F)F)C3)c1)OCOC2 +COc1cc(CNC(=O)CC2C=CCC2)ccc1OC(F)F +CCCNC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +O=C1CCCN1Cc1nnc(SCc2ccc3c(c2)OCCO3)o1 +O=C(NCCc1nc(-c2ccco2)n[nH]1)Nc1ccc(F)cc1Cl +CNC(=O)CN(C1CCCCC1)S(=O)(=O)c1ccc(F)cc1 +Cc1noc(COCC(=O)Nc2c(C)n[nH]c2C)n1 +CC(C)NC(=O)CCC(=O)N1CC2CC(C1)c1cccc(=O)n1C2 +CC(NC(=O)CNC(=O)CC(C)(C)C)c1nncn1C +Nc1ccc2nc(C(F)(F)F)n(CCO)c(=O)c2c1 +CN(CCc1ccncc1)C(=O)Nc1cccc(F)c1 +COc1ccccc1-c1cnc(CNCc2ccccc2)s1 +CCc1cccc(OCC(=O)Nc2ccc(C#N)cc2)c1 +CCN(CCc1cnn(C)c1)Cc1cccc(F)c1 +CCS(=O)(=O)N1CCC(c2cnccn2)CC1 +Cc1ccc(C(C)NC(=O)NCCC(=O)NC(C)C)s1 +COCC(=O)N1CCC(c2cccc(Cc3cccc(F)c3)n2)CC1 +CCC1CCCCN1C(=O)c1ccccc1Br +COC(=O)Cc1ccccc1NC(=O)N(C1CC1)C(C)c1ccco1 +Cc1ccc(N2CC(C(=O)OCCn3cncn3)CCC2=O)cc1C +COc1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)cc1C(C)C +COc1ccc(NC(=O)C(C)Oc2ccc(F)cc2F)c(OC)c1 +CCCc1nnc(NC(=O)c2[nH]c3c(c2C)C(=O)CCC3)s1 +Cc1cc(F)ccc1NC(=O)C(C)n1c(=O)oc2ccccc21 +CC(=O)Nc1ccc(CC(=O)OCCc2cccnc2)cc1 +CCOCC(=O)N1CCC2(CC1)CC(c1ccccc1)CO2 +CC(OCC(F)(F)F)C(=O)Nc1cnn(C(C)(C)C)c1 +CCN(CC)C(=O)CSc1nc(-c2ccccc2)cc(=O)[nH]1 +CCN(CCO)C(=O)c1cc(F)ccc1Br +CC(Sc1ccc(F)c(F)c1)C(=O)Nc1ccnn1C(C)C +COCc1ccccc1CNC(=O)NCC(C)(O)c1ccccc1 +COc1ccccc1C(C)CC(=O)N1C(C)COCC1C +CN(CCC#N)C(=O)c1cc2ccccc2cc1NC(=O)C1CC1 +C=CCNS(=O)(=O)c1cccc(C(=O)NC(C)c2ccncc2)c1 +CCC1C(=O)NCCN1Cc1cnn(-c2ccc(F)cc2)c1 +CC(C)(C)CNC(=O)Cc1csc(N2CCCC2=O)n1 +CCCCn1c(N)c(N2CCC(C(N)=O)CC2)c(=O)[nH]c1=O +Cc1cc(CNS(=O)(=O)c2cc(Cl)ccc2Cl)nn1C +NC(=O)CCN(Cc1ccccc1)C(=O)c1cccc2[nH]ccc12 +Cc1ccc(C(NC(=O)CN2CCCC3(C2)OCCO3)C2CC2)cc1 +COc1ccccc1C1CC1C(=O)Nc1cccc(-n2cnnc2)c1 +Cc1cc(SCC(=O)Nc2ccccc2)n2ncnc2n1 +N#CCc1cc2ccc(Br)cc2[nH]c1=O +CCOC(=O)C1=C(C)N(C)C(=O)N(C)C1c1ccc(C(=O)OC)cc1 +Cc1nc(C)n(CCCNC(=O)c2cc(Cl)c(C)c(Cl)c2)n1 +O=C(c1cccc(Cl)c1)N1CCN(c2ncnc3[nH]cnc23)CC1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)NC1CCCC1 +Cc1ccc(-c2cc(C(=O)N(C)CCC(O)c3ccccc3)n[nH]2)cc1 +CCCc1ccc(NC(=O)C(NC(N)=O)C(C)CC)cc1 +Cc1ncc(C)c(N2Cc3cnc(-c4ccccc4)nc3C2)n1 +Cc1cc(C)c2c(n1)SCC(=O)N2CC(=O)NCc1ccccc1 +CC(=O)N1CCc2c(oc(N)c2C(=O)c2ccccc2)C1 +CCCOc1ccc(S(N)(=O)=O)c2ccccc12 +CCOc1ccccc1C(=O)Nc1c(C(=O)N(C)C)nn(C)c1C +COC1CCN(Cc2cc(C)on2)C2CN(Cc3ccco3)CC12 +CC(C)c1cncnc1N1CC(c2cccnc2)C1 +O=C(NC1CC1)C1CC(=O)N(c2cc(Cl)cc(Cl)c2)C1 +O=C(NCCCN1CCOCC1)c1cccc(-n2cccn2)n1 +COC(CNC(=O)c1ccnc2ccccc12)c1ccccc1 +BrC1(Br)CCCc2ncncc21 +Cc1ccc(C)c(NC(=O)CCNC(=O)c2cc(C3CC3)n[nH]2)c1 +Cc1nccn1-c1ncccc1NC(=O)CNC(=O)CC(C)(C)C +CCc1ccccc1OCCc1ncc(C#N)s1 +COC(=O)c1ccc(Nc2nc(NCCO)c3ccccc3n2)cc1 +CCOc1ccccc1NC(=O)c1cc2ccccc2c(=O)o1 +Cc1nn(C)c2sc(C(=O)N(C)C(C)c3cccnc3)cc12 +CCNC(=O)C1CCCN(C(=O)CCSc2ccccn2)C1 +Cc1ccc(-c2ncc(CN3CCC(n4cncn4)CC3)s2)cc1 +CS(=O)(=O)Nc1ccc(NC(=O)Nc2ccccn2)cc1 +CC(=O)c1ccc(NC(=O)c2sccc2C)cc1 +CCNC(=O)c1cc(-c2ccco2)nc2c1cnn2C(C)C +Cc1noc(C)c1Cn1nnc(C#N)c1-c1cccs1 +Cc1nn(C)c(C)c1CCC(=O)N1CCOC2CCCCC21 +COC(=O)c1cccc(CC(=O)Nc2nn(C(C)C)cc2C#N)c1 +COc1cccc(OCc2nc(C)c(C(C)=O)s2)c1OC +COC(=O)Cn1nc(-c2ccc3ccccc3c2)ccc1=O +CCc1ccc2c(c1)N(CCC#N)C(=O)C(C)(C)O2 +CCn1cnnc1CNC(=O)c1nc(N2CCCC2)ncc1Cl +CCC(=O)Nc1ccc(-c2nnnn2C(C)C)c(F)c1 +OCc1nnn(Cc2ccc(F)cc2)c1CCc1ccccc1 +CC1CCN(C(=O)C2CC(=O)N(CCc3ccc(F)cc3)C2)CC1 +COCCCNC(=O)CSc1nnc2[nH]c3ccccc3n12 +CCOCC(O)CN1CCN(C(=O)Cc2ccc3c(c2)CCC3)CC1 +CCC1CCCCN1S(=O)(=O)c1ccc2c(c1)NCC(C)O2 +Cc1ccsc1C(=O)N1CC2CC1CC2NS(C)(=O)=O +Cc1cc(-c2nnc(CCC(=O)Nc3cccnc3)o2)n(C)n1 +Cc1ccc(CC(C#N)Sc2nnnn2-c2ccc(O)cc2)cc1 +Cc1ccc2cccc(C(=O)NCc3cc(C)oc3C)c2n1 +COc1ccc(NC(=O)c2ccc(OC)c(OC)c2)cn1 +COc1nccc(N(C)C)c1NC(=O)c1occc1Br +COc1cc(C)ccc1Oc1ccc(F)cc1NCc1ncnn1C +Cn1cc(S(=O)(=O)N2CCCC2CC(O)c2ccccc2)cn1 +O=C(NCc1ccncn1)c1cn(C2CCCCC2)nn1 +COc1ccc(CCNc2ncnc(N(C)C)c2N)cc1OC +Cc1occc1C(=O)NC(C(N)=O)c1ccc(F)cc1 +COc1ccc(C(F)(F)F)cc1-c1cccc(=O)[nH]1 +CCCCS(=O)(=O)N1CC(c2nc(-c3cnccn3)no2)C1 +COc1ccccc1-c1noc(C2CC(=O)N(CC(F)(F)F)C2)n1 +CC1CCC(NC(=O)CNc2c(F)cccc2F)CC1 +CN(C)C(=O)c1ccc(N(C)S(C)(=O)=O)cc1Cl +Cc1cccc(OC(=O)Cn2c(=O)n(C)c3ccccc32)c1C +N#Cc1c(COC(=O)C2(O)CCCCC2)cn2ccccc12 +CC(=O)Nc1ccc(Cl)c(C(=O)NCc2csc(=O)[nH]2)c1 +CC1CCN(C(=O)C(C#N)Cc2ccc3c(c2)OCCO3)CC1 +COc1ccc(CN(C)C(=O)c2cn3cccnc3n2)cc1 +C=CCN(c1ccc(C(=O)Nc2ccccc2F)cc1)S(C)(=O)=O +CC(=O)NC(CC(=O)Oc1c(C)ccc(C)c1C)c1ccccc1 +O=C1COc2cc(C(=O)NCC3CCC3)ccc2N1 +COCC(C)OCc1cc2c(cc1Br)OCO2 +CNc1cc(C2CN(S(=O)(=O)c3cn[nH]c3)CCO2)nc(C)n1 +Cc1nnc2n1CCN(CC(=O)N(C)Cc1cccs1)C2 +Cc1noc(COCC(=O)NCCN2CCOCC2)n1 +COc1ccc(OC(=O)n2c(=O)oc3cc(C(C)=O)ccc32)cc1 +CCOc1ccccc1NC(=O)c1cn(C)nc1C +Cc1ccc(NC(=O)CCOc2cccc(Cl)c2)nc1 +COc1ccccc1OCC(=O)NCc1cccc(C#N)c1 +Cc1ccc2oc(SCC(=O)N3CCCCC3C(N)=O)nc2c1 +COC(=O)c1cccc(CN2CCCC2C(=O)OC)c1 +Cc1cc(Br)cc2c1CCNC2c1ccoc1 +COc1ccc(-c2n[nH]c3c2C(c2cccc(O)c2)N(C)C3=O)cc1 +CCCC(=O)N1CCN(c2ccc(N3CCCC3)nn2)CC1 +CNC(=O)Nc1ccc(NC(=O)c2ccc(-n3cccn3)cc2)cc1 +COc1ccc2c(=O)n(Cc3cscn3)ccc2c1OC +CCC(O)CN1CCN(C(=O)c2sccc2C(C)C)CC1 +CCN(Cc1ccc(OC)c(F)c1)C(=O)Cn1cnc(C#N)n1 +O=C1C(Sc2nncc3ccccc23)CCN1c1ccccc1F +C#Cc1cccc(N(Cc2cccs2)C(=O)Cn2cnnn2)c1 +CCCC(=O)N1CCc2c(CNS(C)(=O)=O)cncc2C1 +CCOCCCNC(=O)N1CCC(c2nc3ccccc3s2)CC1 +CCc1n[nH]c(C2CN(Cc3nc4ccccc4c(=O)[nH]3)CCO2)n1 +CCCCCNS(=O)(=O)c1ccc(NC(C)=O)cc1 +COC(=O)CCCN(C)C(=O)C#Cc1ccccc1 +CCOc1ccccc1NC(=O)Nc1cc2[nH]c(=O)[nH]c2cc1C +CC(C)NC(=O)Nc1ccccc1C(=O)NCc1ncn(C)n1 +COCC(=O)NCc1ccc(C(=O)N2CCCC2)cc1 +CN(C)c1ccc(C#CCNC(=O)CC2CCCC2)cc1 +O=C(NCc1ccncc1)NCC1(O)CCCCC1 +CC(=O)c1c(F)cccc1N(C)Cc1cccnc1 +O=C1CN(S(=O)(=O)CCn2nnc3ccccc32)CCN1 +CCc1nnc2n1CCN(C(=O)c1ccc3cc[nH]c3c1)C2 +COc1ccc(C(=O)CN2CCc3ccccc3C2)cc1 +O=C(CSc1ccc(F)cc1)Nc1ccccc1-n1cnnn1 +Cc1nc(N2CCCCC2)ncc1C(=O)NC1CCCC1 +COc1ccc(OC)c(NC(=O)c2cnc(C)cn2)c1 +CC(=O)Nc1cccc(NC(=O)c2sc(C)nc2C)c1C +CNc1sc(C(=O)c2ccc(OC)cc2)c(C)c1C(=O)OC +CC(C)(C)OC(=O)N1CCN(c2c(N)cccc2Cl)CC1 +Cc1ccc(C(=O)N2CCC3(CC2)NC(=O)CC3c2ccccc2)o1 +Cc1nc2ccccc2n1CCCNC(=O)N1CCOCC1C1CC1 +CC(C)NC(=O)Nc1ccc(NC(=O)COC2CCCCC2)cc1 +CCC(CNC(=O)c1snnc1C)(OC)c1ccccc1 +CN(Cc1ccncc1)C(=O)c1c[nH]nc1-c1cccc(Cl)c1 +COCc1nc2ccccc2n1CC(=O)Nc1cccc(Cl)c1 +COc1ccc(N)c(C(=O)NC2(CO)CCCC2)c1 +CC(=O)NCCNC(=O)CCn1c(C)csc1=O +CNc1nnc(-c2cnc(-c3ccncc3)s2)s1 +Cc1ccsc1C(=O)N1CCC(c2noc(C(C)C)n2)CC1 +Cc1ccc(OCCC(=O)NC(C)(C)C(N)=O)c(Br)c1 +Cc1ccc(S(=O)(=O)N=c2n(C)c3ccccc3n2C)cc1 +COc1cc2c(cc1OC)C1C3CC=CCC3C(=O)N1CC2 +CC(C)c1nc(CCNC(=O)c2ccc(-c3cc[nH]n3)cc2)cs1 +COc1ccccc1N1CCN(C(=O)c2cc(C)sc2C)CC1 +CCOc1ccc(-n2nnnc2CNC(=O)CC2CCCC2)cc1 +CCc1nnc(NC(=O)Cc2ccc(Cl)cc2Cl)s1 +CCCNC(=O)C1CCN(C(=O)Nc2ccc(C)c(Cl)c2)CC1 +COc1ccc(-c2nc(CC(=O)N3CCOC(C)(C)C3)cs2)cc1 +COc1ccc(S(=O)(=O)NCc2ccc(OC)c(OC)c2)cc1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCc1nc(C2CC2)no1 +COc1ccc(C2(C(=O)NCc3cccs3)CCOCC2)cc1 +COCCN(C)C(=O)Nc1nnc(Cc2ccc(F)cc2)s1 +O=C(NCCOC(=O)c1ccc(F)cc1F)c1ccncc1 +O=C(C1CC1)N1CCC2(CCN(Cc3cccc(F)c3)C2=O)C1 +CCc1ccc(N)cc1S(=O)(=O)NCCC(N)=O +O=C(CNC(=O)NCCCO)Nc1ccc(Cl)cc1 +Cc1ccc(OCCNC(=O)C(NC(N)=O)C(C)C)cc1 +CCOC(=O)c1c(NC(=O)C2CC3CCC2C3)sc(C(C)=O)c1C +O=C(CC1CCCC1)NCCNC(=O)N1CCCCC1c1cn[nH]c1 +Cc1cc(NC(=O)C2CCCO2)n(C(C)(C)C)n1 +CCOc1ncccc1C(=O)OCC(=O)Nc1ccc(C)c(Cl)c1 +CN(C(=O)c1ccc(Br)cn1)c1ccc(F)cc1 +O=C(NCc1ccccc1F)c1cnn(-c2ccccc2)n1 +O=C(Nc1ccc2c(c1)OC1(CCCC1)O2)C1CCOCC1 +CCNC(=O)c1c(C)nc(N)nc1-c1cccs1 +CCC(C(=O)NC1CC1)N(c1cccc(Cl)c1)S(C)(=O)=O +Cc1ccc(NC(=O)C2CCN(C(=O)Nc3cccnc3)CC2)nc1 +CC(C)(C)C(=O)CSc1nc(Cc2cccs2)n[nH]1 +CNC(=O)c1cc(NC(=O)c2ccc(C)s2)ccc1Cl +NC(=O)c1cccc(CNC(=O)N(Cc2ccccc2F)C2CC2)c1 +O=C1Nc2cccc(Br)c2C1Nc1ccc(F)c(F)c1 +COC(=O)c1ccc(C(=O)Nc2ccccc2NS(C)(=O)=O)cc1 +CCCN1C(=O)Cc2cc(C(=O)N3CCC(C)CC3)ccc21 +Cc1nc(NCCC(C)C)sc1C(=O)NC1CC1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCc1cn2ccccc2n1 +CC(C)(CO)NC(=O)Nc1ccccc1OC(F)F +O=C(Nc1ccccc1O)c1ccc(F)cc1-n1cnnn1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2nc3c(s2)CC(C)CC3)c1C +N#CC1(C(=O)NCc2cccc(Cl)c2)CCCC1 +CSc1ccc(OC(C)c2nc(-c3ccc(C#N)cn3)no2)cc1 +c1ccc(-c2cc(NCc3cccnc3)ncn2)cc1 +CN(CCc1nccs1)Cc1nnc(-c2ccccc2)n1C +CCN(C(=O)Cc1cccc(S(=O)(=O)CC)c1)c1ccc(F)cc1 +CCCCN(CCO)C(=O)Nc1cc(OC)ccc1F +CCOC(=O)CNC(=O)NCc1ccnc(C)n1 +Cc1cncc(NCC2CCN(S(=O)(=O)c3ccccc3)CC2)n1 +COc1ccc(NC(=O)N(CCC#N)Cc2ccco2)cc1 +Cc1coc(N)c1C(=O)c1cncc(Br)c1 +CCOc1ccc(OCC(=O)N2CCC(Cn3cccn3)CC2)cc1 +COc1ccc(S(=O)(=O)Nc2cc(C)ccc2O)cc1 +Cc1nnc(N2CCN(Cc3ccsc3)CC2)c(C#N)c1C +CC(=O)Nc1ccccc1OCc1csc(-c2cnn(C)c2)n1 +Cc1nn(CCc2ccc3c(c2)ncn3C)c(C)c1N +Cn1nccc1C(=O)NCC(=O)NC1CCCC1 +C#CCNC(=O)N1CCC(Nc2cc(OC)cc(OC)c2)CC1 +Cc1c(-c2noc(C(=O)N3CCCC3)n2)oc2c(C)cccc12 +Cc1nc2cccc(NC(=O)CCc3nc4cc(C)c(C)cc4[nH]3)c2[nH]1 +CC(=O)Nc1cccc(Nc2ccc(Br)cn2)c1 +CN1C(=O)NC2c3ccccc3OC1(C)C2C(=O)Nc1ccccc1 +Cc1noc(-c2ccccc2C(=O)N(C)CCOCC2CC2)n1 +CCc1cc2c(=O)n(Cc3nc(C)c(C)s3)cnc2s1 +COc1ccc(CCNC(=O)N2CCOCC2)cc1OC +CC1(C)C2CCC1(C(=O)N1CCCc3ccccc31)C(=O)C2 +CCc1onc(C)c1NC(=O)Cc1c(C)nn(C)c1C +CN(Cc1ccc(F)c(F)c1)S(=O)(=O)c1ccccc1 +Cc1nc(C)c(C(=O)OCC(=O)Nc2ccc3c(c2)CCC3)s1 +Nc1ncccc1C(=O)OCC(=O)N1CCCCCC1 +CCCc1nc(NC(=O)NC2CCN(C(=O)CC)C2)sc1CC +Cn1cc(NS(=O)(=O)c2c(Cl)cc(Cl)cc2Cl)cn1 +Cc1ccc(C(C)NC(=O)Cc2c(C)[nH]c3ccnn3c2=O)cc1F +Cc1cnn(CC2CCCN2C(=O)c2cnn3ccc(C)nc23)c1 +Cc1cn(C)nc1C(=O)Nc1nc2c(C)cccc2s1 +O=C(NCCCNC(=O)C1CCCCC1)c1cnc2[nH]ccc2c1 +Cc1cc(C(=O)CN2CCN(c3ccccc3)CC2)c(C)[nH]1 +COC(=O)C1CN(C(=O)c2ccc(F)c(F)c2F)c2ccccc21 +CCN(CC(=O)NC)C(=O)c1cc(Br)cn1C(C)C +Cn1cccc(NC(=O)NCCc2ccccc2F)c1=O +CCCCS(=O)(=O)c1ccc(C(=O)CC(C)C)cc1 +Cc1nc(-c2ccccc2)ccc1C(=O)N(C)C(C)C +O=C(CNC(c1ccccc1)c1ccccn1)N1CCOCC1 +CC(=O)NCCc1ccc(-c2csc(NC(C)=O)n2)s1 +COc1ccc(CNC(=O)C2CC=CC2)cc1OC +O=C(CSc1nnc(C2CC2)s1)NCc1cccnc1 +CN(CC(=O)NCC1CC1c1ccccc1)c1ncnc2[nH]cnc12 +Cc1ccsc1C(=O)NCc1ccnc(OC2CCOCC2)c1 +Cc1cc(C(=O)Cn2cnc(C3CCC3)cc2=O)c(C)n1C1CC1 +CCN(C(=O)CCc1ccc(OC)c(N)c1)c1ccccc1 +CCCNC(=O)CN(c1ccc(C)cc1)S(=O)(=O)N(C)C +COCc1c(C(=O)NCC2CCC2)oc2ccccc12 +CC(C)(O)CNC(=O)NC1CCN(c2c(F)cccc2F)C1=O +COC(=O)c1ccc(-n2nc(C(N)=O)cc2N)cc1 +CCc1c(C)nc(-c2ccc(F)cc2)n2c(=O)[nH]nc12 +CC(=O)c1sc(COc2ccc(C)cc2)nc1C +COc1ccc(OC)c(COC(=O)Cn2c(C)c(C)sc2=O)c1 +COc1ccc(CCC(=O)Nc2ccc(O)cc2C)cc1 +CC1(C)CC(CCC(=O)Nc2ccc(S(N)(=O)=O)cc2)C(=O)O1 +CC(C)c1noc(CS(=O)(=O)c2ccc3c(c2)OCCO3)n1 +O=S(=O)(N1CCCCC1)N1CCC(Oc2cnccn2)CC1 +CCC(=O)Oc1ccc(C(=O)Nc2cccc(C)n2)cc1 +COC(=O)c1cn(C2CC2)cc(C(=O)OC)c1=O +O=C1CCS(=O)(=O)N1c1ccc(F)c(Cl)c1 +Cc1[nH]nc(C(N)=O)c1NC(=O)c1cc(C)n(-c2ccccc2)n1 +CN(CCN1CCCCC1=O)c1ncnc2[nH]ccc12 +Cc1nc(N(C)CC(=O)N(C)C)c2c3c(sc2n1)CCC3 +Cc1cc(C(=O)Nc2cnc3n2CCCC3)ccc1F +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)Cn1cncn1 +Cc1cc(Br)cc(C)c1NC(=O)NCc1cccn1C +CC1COCC(C)N1C(=O)c1cccc(-c2ccoc2)c1 +CCOC(=O)c1sc(Oc2ccc(C)nc2)nc1C +Cn1nc(C(=O)NCCSc2ccc(Cl)cc2)ccc1=O +Cc1ccoc1C(=O)N(CCC#N)CCC(F)(F)F +O=C(Nc1cccc(F)c1F)c1ccc(=O)[nH]c1 +COCCN1CCN(C(=O)c2ccnnc2)CC1=O +Cc1cccc(NC(=O)N(C)Cc2ccncc2)c1C +C=CCCCN(C)C(=O)c1ccc(N2CCCS2(=O)=O)c(C)c1 +O=C(CNC(=O)c1ccccc1)Nc1ncccc1O +O=C(NCCOc1ccc(Cl)cc1)c1ccc2ccnn2c1 +CS(=O)(=O)c1ccc(Cl)c(NC(=O)COC2CCCCC2)c1 +O=C(Cc1c[nH]c2ccccc12)OCC(=O)c1ccccc1F +CC(CCc1ccccc1)NC(=O)N(C)Cc1ccccn1 +CCOCCNC(=O)NCc1ccc(OC)cc1 +CC(=O)c1cc(C#N)c(SCc2nc(C)c(C)o2)nc1C +CCC(CC)NC(=O)C(C)Sc1ccc(N)cc1C +Cc1cccc(C2NCCc3cc(F)c(F)c(F)c32)n1 +Cn1nnc(-c2cccc(NC(=O)CCNc3ncccn3)c2)n1 +CS(=O)c1nncn1CCC(=O)NCC1CCCCC1 +COc1ccc(-c2cnc(-n3cnnc3)c(C)c2)cc1Cl +CC(=O)c1ccc(C(=O)NCc2ccc(-n3ccnc3)cc2)cc1 +Cc1cc(NCc2ccccc2OC(F)F)ccc1-n1cnnn1 +COc1ccc(NC(=O)COc2cccc(C)c2)cc1OC +Cc1nnc(NC(=O)c2cccc(Oc3ccccc3)c2)s1 +Cc1ccc(-n2cc(C(=O)NCc3cn4ccsc4n3)nn2)cc1 +O=S(=O)(NCc1ccccc1F)c1ccc(F)c(Cl)c1 +CCN(CCC(=O)OC)C(=O)c1cc(F)ccc1F +COC(=O)C1=C(C(C)C)NC(=O)NC1c1ccccc1Cl +FC(F)(F)Cn1ccnc1CSc1nnnn1C1CCOCC1 +COc1ccc(C(=O)Nc2cc(C)nn2-c2ccc(C)nn2)c(C)c1 +Cc1ncsc1CNS(=O)(=O)c1ccc(OC(C)C)cc1 +CC(c1ccc(C#N)cc1)N1CCN(C(=O)c2ccc(O)cc2)CC1 +NS(=O)(=O)CCNC(=O)Cc1ccc(C(F)(F)F)cc1 +Cc1nc(C#N)c(N2CCN(C(=O)CN3CC(C)OC(C)C3)CC2)o1 +COc1cccc(C(C)Cc2nc(-c3ccc(C#N)cn3)no2)c1 +Cc1cc(C)cc(CCNS(=O)(=O)CC2CCOC2)c1 +COc1cc(OC)cc(C(=O)NC2CCCc3ccccc32)c1 +COC(=O)C(NC(=O)C1Cc2ccccc2O1)c1cc(F)ccc1F +CCCS(=O)(=O)N1CCN(Cc2cc(C)on2)CC1 +CCNC(=O)CSc1nnc(Nc2ccc(OC)cc2)s1 +NC(=O)Nc1cccc(NC(=O)c2cccc(Cl)c2)c1 +CC(OC(=O)CC1C=CCC1)C(=O)Nc1ccccc1C#N +CCN(Cc1ccccc1NC(=O)NC(C)(C)CO)C(C)=O +CN(Cc1ccc(F)c(F)c1)CC(O)c1ccccc1Cl +CCN(C(=O)Cc1ccc(S(=O)(=O)C(F)F)cc1)C(C)C(C)C +Cc1ccc(N)c2ccnc(C(=O)NCCN3CCOCC3)c12 +CC(C)NC(=O)NCC1CCN(C(=O)c2cc3ccccc3o2)CC1 +CNC(=O)COc1cc(C(=O)NCC(C)C)ccc1N +CC1CCN(S(=O)(=O)NC(C)C(=O)NC(C)(C)C)CC1 +Cc1cc(C(=O)CN2CCC(NC(=O)c3ccccc3)CC2)c(C)[nH]1 +COC(=O)C(Sc1ccccn1)c1ccccc1 +Cc1ccc(C(=O)Nc2cccc(Oc3ncccn3)c2)cc1 +CCC(Sc1ncccn1)C(=O)Nc1nccs1 +CCC(=O)N(Cc1cc2cc(C)ccc2[nH]c1=O)c1ccc(C)cc1C +CCOc1ccc(NC(=O)Nc2ccc3c(c2)oc(=O)n3CC)cc1 +C#CCn1nc(CO)cc1-c1ccc(Cl)cc1Cl +Cc1cc(C)c(NC(=O)NC2COc3ccccc3C2)c(C)c1 +Cc1ccc(OCC(=O)NC2CCOCC2)c(C(=O)NCC(C)C)c1 +Cc1cnc(C(=O)NCC2Cc3ccccc32)cn1 +CNC(=O)CNC(=O)c1ccc(Oc2ccccc2)cc1 +Cc1ccccc1C(=O)N1CCC2(C1)C(=O)Nc1ccccc12 +CN(C)C(=O)CN(C)S(=O)(=O)c1c(Cl)cccc1Cl +CC(C)(C)C(=O)NCCC(=O)N1CCN(C(=O)c2ccco2)CC1 +CC(C)C(NC(=O)c1ccccn1)c1ccc2c(c1)OCCO2 +O=S(=O)(N1CCCC1)N1CCN(c2ccccc2)CC1 +CCN(Cc1cccc(C)c1)C(=O)c1cn(CC(=O)N(C)C)nn1 +CCOc1ncccc1C(=O)N(C)Cc1cnn(C)c1 +CCOC(=O)C(Cc1ccc(C)cc1)c1nc2ccccc2[nH]1 +COCCNc1nc(-c2cnc(COC)s2)cs1 +CCOC(=O)CNS(=O)(=O)c1c(C)nn(C)c1C +Cc1ccoc1CN(Cc1cccnc1)CC1CCCO1 +COc1cccc(CNC(=O)c2cc3ccccc3o2)c1 +COCC(C)NC(=O)COc1ccc(-c2nnco2)cc1 +CCCCc1c(CO)nnn1Cc1ccc(F)cc1 +Cc1ccc(F)c(NC(=O)N2CCC(N3CCOC(C)C3)CC2)c1 +Cc1ccc(NC(=O)NCC(C)(C)NS(C)(=O)=O)cc1F +CS(=O)(=O)N1CCCN(C(=O)c2csc3ccccc23)CC1 +C=CCOc1ccc(Br)cc1CNn1nnnc1N +O=C(NCc1cccs1)c1cccc(NC(=O)C2CCCO2)c1 +O=C(Nc1cnn(CCc2ccccc2)c1)c1ccc2c(c1)OCCO2 +CC(C)N(CC(N)=O)S(=O)(=O)c1ccc(Cl)c(Cl)c1 +COc1ccc(C(=O)N(C)Cc2cc(C)on2)c(Br)c1 +CC(C)OCc1cccc(NC(=O)CNC(=O)C2CCCC2)c1 +CC(c1cnn(C)c1)n1ccnc1-c1cc(F)ccc1-n1cccn1 +COc1ccccc1-c1nnc(NC(=O)c2cccc(C)c2)o1 +Cc1csc(N2CCN(c3nnc(C)c(C)c3C#N)CC2)n1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cnc2[nH]nc(C)c2c1 +O=C(Nc1ccc2c(c1)COC2)C1CCCN1C(=O)c1ccccn1 +CC(C)(C)OC(=O)CNC(=O)Cc1ccc(F)c(F)c1 +COc1cc(NC(=O)N2CC(c3nc(C)no3)C2)cc(OC)c1 +CCc1ccc(CN(C)C(=O)Nc2c(OC)nn(C)c2C)nc1 +O=C(Nc1nc(C(=O)Nc2ccc(F)cc2)co1)c1ccccc1 +CN(Cc1ccccc1)C(=O)NCCCS(=O)(=O)c1ccccc1 +Cc1nn(CC(=O)NC2CCOCC2)c(=O)n1CCc1ccccc1 +O=C(NCCC(=O)N1CCCC1)c1cc2sccn2c1 +CCCOc1cccc2c1C(c1cncnc1)NCC2 +CC(C)=CCOc1cccc(C(=O)N2CCC(n3cncn3)CC2)c1 +Cc1cnc(NC(=O)Cn2cc(Br)ccc2=O)s1 +CCCCCCNC(=O)Cc1nc2nc(C)cc(C)n2n1 +COc1ccc(OCCN2C(=O)CCS2(=O)=O)cc1 +COc1ccc(C(NC(=O)NCCNC(C)=O)c2nccn2C)cc1 +CCOc1cc(F)ccc1NC(=O)c1ccc(C(=O)OC)cn1 +Cc1cc(C)n(-c2ccc(NC(=O)c3c[nH]c4cccc(F)c34)cn2)n1 +Cc1cccc(CC(=O)Oc2ccc3c(c2)ncn3C)c1 +Cc1ccc(SCC(=O)c2c(N)n(C3CC3)c(=O)[nH]c2=O)cc1 +CC(C(=O)N(C)CCC#N)N1CCCc2ccccc21 +N#CC(NS(=O)(=O)c1ccccc1)c1cccnc1 +Cc1ccccc1-c1csc(=O)n1Cc1nnc(C2CC2)n1C +Cc1ccc(SCCN2CCCC3(C2)OCCO3)cc1C +Cc1[nH]ncc1CCCNC(=O)CCn1cccn1 +O=C(CCc1nc(-c2ccccc2)no1)Nc1ccc2ncccc2c1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCNC(=O)C1c1ccccc1 +COc1ccc(CN(C)C(=O)c2ccc(OCC(F)F)nc2)cc1 +CC(C)(C)Oc1cc(CNC(=O)C2Cc3cc(F)ccc3O2)ccn1 +Cc1cccc(C(N)C(=O)NCC(C)C)c1Cl +N#CC1(C(=O)Nc2ccccc2OCC2CC2)CCCC1 +COCc1nnc(NC(=O)CCc2ccc(-c3ccccc3)o2)s1 +O=S(=O)(CC1CCCC1)NCc1cn(-c2ccccc2)nn1 +O=C(NCCc1ccc(F)cc1)c1nc[nH]c1-c1cccnc1 +CCOc1ccccc1N1CCN(C(=O)c2ccccc2)CC1 +Cc1nnc(CNC(C)c2nc(-c3cccc(F)c3)no2)o1 +CN(C)C(=O)C(O)(c1ccccc1)C1(O)CCCC1 +COc1ccccc1-c1ccc(=O)n(CC(=O)N2CCOCC2)n1 +Cc1ccccc1C1(CNC(=O)N2CCNC(=O)C2)CCOCC1 +CC(NC(=O)COC1CCCC1)C(=O)NC(C)(C)C +COC(=O)Cn1ncn2c(cc3sc(C)cc32)c1=O +COc1ccc(-c2cn3c(N)csc3n2)cc1F +Cc1cc(C)nc(N(C)Cc2nccn2C(F)F)n1 +CCN1C(=O)Cc2cc(C(=O)NCC3CCCCC3)ccc21 +Cc1cccc(NC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)n1 +CCOc1ccc(C(C)NC(=O)c2c(C)noc2C)cc1 +CC1(C)C2CCC1(C(=O)Nc1ccc(OC(F)(F)F)cc1)C(=O)C2 +CCNc1cncc(S(=O)(=O)N(CC)CC)c1 +O=C(CCc1cn2cccnc2n1)NCc1cccc(C(F)(F)F)c1 +Cc1ccc(C(C)NS(=O)(=O)N2CCCCC2)o1 +O=C(NCc1ccncc1)Nc1cc(Cl)cc(Cl)c1 +CN(Cc1cccc(Cl)c1)C(=O)c1cccc(C#N)c1 +CN(CCC#N)C(=O)c1ccc(OCc2ccccc2C#N)cc1 +CCC1CCCCN1C(=O)c1cccnc1SC +Cc1noc(C)c1NC(=O)N(C)CCOc1ccccc1F +COc1cccc(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)c1 +CC(=O)c1cccc(OC(C)C(=O)Oc2ccc(C#N)cc2)c1 +O=C(CSc1ccc(Cl)cc1)N1CCCC(O)(CO)CC1 +CCC(C)NC(=O)c1ccc(NC(=O)C2CCN(C(C)=O)CC2)cc1 +Cc1cccc(OCCNC(=O)NC(C)c2nc3ccccc3[nH]2)c1 +CS(=O)(=O)N1CCC(c2ccnc(Cc3ccccc3F)c2)CC1 +O=C(NC1CCSc2ccccc21)c1scnc1C1CC1 +Cc1cc(COC(=O)C2CCCN2C(=O)c2ccccc2O)no1 +CS(=O)(=O)N(CC(=O)N1CCCC1)c1ccc(F)c(Cl)c1 +CC(C)CCC(=O)Nc1nc(-c2ccccn2)cs1 +Cc1n[nH]c(C)c1CC(C)C(=O)Nc1ccc2[nH]nnc2c1 +CC(=O)c1csc(C(=O)NCc2nnc(-c3ccccc3)s2)c1 +CN1CCC(Nc2nc(-c3ccncc3)nc3c2CCC3)C1=O +CNC(=O)CCCC(O)c1cc(F)ccc1OC +CC(C)CC(=O)Nc1nc(C(=O)N(C)CCc2ccccn2)cs1 +CCn1cc(Cl)c(C(=O)NCc2cc3ccccc3[nH]2)n1 +O=C(OCc1cc(-c2cc3ccccc3o2)on1)c1ccno1 +CCOc1ccc(Cl)c2c1CCNC2C1CCOCC1 +CC(=O)Nc1ccc(O)c(C(=O)NCCOc2ccccc2)c1 +COc1ccc(C(=O)Nc2ccc(Cl)cc2NC(C)=O)nn1 +CC(NC(=O)c1cc2c(s1)CCC2)C(=O)NCc1ccccc1 +Cc1cnn(-c2ccc(NC(=O)c3ccncc3F)cc2F)c1 +Cc1cccc(NC(=O)CCn2c(=O)c(C)nc3ccccc32)c1 +CCOc1cc(N)c(NC(=O)CC(C)C)cc1OCC +Cc1nc(C(C)C)ncc1C(=O)N1CCC(C)(O)C(CC(C)C)C1 +Cc1ccccc1CNS(=O)(=O)Cc1ccc(F)cc1 +CC(=O)NC12CC3CC(C1)CC(C(=O)Nc1nnc(C)s1)(C3)C2 +CC1CN(C(=O)c2cc(NC(=O)c3ccccc3)n(C)n2)CC(C)O1 +O=C(CCCn1c(=O)oc2ccccc21)N1CCc2sccc2C1 +CC(NC(=O)c1scnc1C1CC1)c1cccc(Cl)c1 +CC1CN(C(=O)c2cc3ccccc3oc2=O)CC(C)O1 +N#Cc1cc(F)ccc1CN1CCn2c(nnc2C2CC2)C1 +CCCn1c(C)nnc1SCC(=O)NCC1CCCCC1 +Cc1nn(C)c2nc(-c3cccs3)cc(C(N)=O)c12 +Cc1c(C)n2c3c(=O)n(C)c(=O)n(C)c3nc2n1Cc1ccccc1 +CC(=O)NCc1cc(=O)[nH]c(C2CN(Cc3ccccc3)CCO2)n1 +Cc1ccc(S(=O)(=O)NC(C)(C)c2nc(C)c(C)s2)cc1F +Cc1c(C(=O)Nc2ccc(F)c(F)c2)sc2ncn(C)c(=O)c12 +O=C(CSc1ccc2ccccc2c1)Nc1ccccn1 +Cc1ccc(CNc2ccc(C(N)=O)cc2)cc1F +CCN(CCC(=O)OC)C(=O)c1cn2c(C)cccc2n1 +COC(=O)Cc1ccc(Nc2nc3cc(OC)c(OC)cc3[nH]2)cc1 +COc1cc(O)ccc1-c1c(C#N)c(N)nc2c1Cc1c(O)cccc1-2 +COc1cccc(OC)c1C(=O)N1CCc2ccc(N)cc21 +CCC(O)CN1CCOC(CCc2ccccc2)C1 +CCOc1ccc(NC(=O)c2ccc(F)c(COC)c2)cc1F +Cc1ccncc1NC(=O)NC1CCN(c2c(F)cccc2F)C1 +COc1ccc(OC)c(NC(=O)c2cnc3ccccc3n2)c1 +Cc1ccc(NC(=O)C2CC(=O)N(CCN3CCOCC3)C2)cc1F +Cc1cc(C)cc(NC(=O)CNC(=O)Cc2ccccc2)c1 +COc1ccc(C(=O)NCCO)cc1C(C)(C)C +Cc1cc(C)c(NC(=O)C(O)c2ccc(F)cc2)c(C)c1 +O=C(NCCN1CCOCC1)c1cnc(Nc2ccccc2)nc1 +COCCN(Cc1nccs1)C(=O)CC12CC3CC(CC(C3)C1)C2 +O=C(CCOCC1CCCO1)N1CC=C(c2ccccc2Cl)CC1 +Cc1cc(CNC(=O)CCCc2nnc(-c3ccccc3)o2)c(C)o1 +CCCC(=O)N1CCCC(C(=O)Nc2ccccc2C(N)=O)C1 +CCOc1ncccc1C(=O)Nc1nc(C)c(C(=O)OC)s1 +Cc1nc(-c2cccc(NC(=O)CCCc3ccccc3)c2)n[nH]1 +CC(Oc1ccccc1C#N)C(=O)Nc1ccc(-c2nncn2C)cc1 +CC(=O)Nc1ccc(F)c(NC(=O)CC2OC(=O)c3ccccc32)c1 +CCc1nc(CCOc2ccccc2OC)sc1C#N +CCOc1ncccc1-c1nc2c(cc1C(N)=O)CCC2 +O=C(NCCOc1ccccc1)c1ccccc1-n1cnnn1 +Cc1noc(C)c1CN1CCCN(S(=O)(=O)c2ccccc2)CC1 +CNc1nc(-c2ccc3c(c2)ncn3C2CC2)cs1 +Cc1cc(C)n(CCCNC(=O)Nc2cccc3[nH]ncc23)n1 +CNC(=O)Nc1ccc(C2(C(=O)NC3CCCCC3)CCC2)cc1 +CCC(C)Nc1ncnc(NCc2ccc(Cl)cc2)c1N +CC(C)COCCNC(=O)NCC(=O)N1CCCC1 +COc1c(Br)cccc1C(=O)C(C)N +Cc1ccc(NC(=O)Nc2ccccc2)cc1NC(=O)c1cc[nH]n1 +COC(=O)Cc1c(C(=O)OC)nnn1-c1ccc(OC)cc1 +CC(=O)Nc1ccc(F)c(C(=O)N(C)CCOc2ccccc2C)c1 +Cc1ccc2ncc(C(=O)N3CCN(c4nccs4)CC3)n2c1 +CC(C)c1cc(C(=O)N2CCC(Sc3ccccn3)CC2)n[nH]1 +Cc1cc(NCCN2CCOCC2)n2c(n1)nc1ccccc12 +Cc1c(C(=O)NC(C)c2ccc(C#N)cc2)sc2nccn12 +Cc1ccc(N2CC(C(=O)Nc3ccc(C)cn3)CC2=O)cc1 +COC(=O)c1ccc(Cn2cnc(C3CCC3)cc2=O)o1 +CCCCc1ccc(NC(=O)Cc2nc(CO)cs2)cc1 +Cc1ccc(-n2nc(C)cc2NC(=O)Cn2ncc3cccnc32)cc1 +Cc1cc(NC(=O)c2csnn2)n(-c2ccccc2F)n1 +COC(=O)CNC(=O)Cn1ccc2ccc(F)cc21 +Cc1cc(N2CCOCC2)nc(NCc2ccco2)c1C#N +Cc1cc(C(=O)N2CCCC2)c2c(C)nn(C(C)(C)C)c2n1 +O=C(NCC1CCC1)c1ccc(Cn2cc(Br)cn2)o1 +COCc1nc(CCc2ccccc2)sc1CC#N +CCOC(=O)c1cccc(NC(=O)c2ccc(OC)cc2)c1 +CS(=O)(=O)N1CC2COCC2(CNC(=O)c2ccno2)C1 +CC(Sc1nnnn1-c1ccccc1)C(=O)c1ccccc1 +CN1CCOC2CN(C(=O)C3COc4ccc(F)cc4C3)CC21 +C#CCNC(=O)c1ccccc1SCC(=O)NCC1CCCCC1 +O=C(CCSc1nc(Cc2cccs2)n[nH]1)Nc1ccccc1 +CCOC(CC)C(=O)NCc1cn2cc(Br)ccc2n1 +CCCCCNC(=O)Cc1noc2c(C(C)C)cc(N)cc12 +CCCCNC(=O)c1cccc(S(=O)(=O)N2CCCCCC2)c1 +Cc1cnccc1CCNC(=O)NC1CCCC(C(=O)NC(C)C)C1 +Cn1ccc(C(=O)Nc2nc3c(Br)cccc3s2)n1 +CC(NC(=O)c1ccoc1)C(=O)NCC(C)(O)c1ccc(F)cc1 +Cc1cc(CCNC(=O)c2cc3ccccc3[nH]2)on1 +COc1ccccc1C(C)NC(=O)CC(NC(C)=O)c1ccccc1 +C#CCNC(=O)CSc1nnc(N)n1CC=C +CN(Cc1ncnn1C)C(=O)NCCOc1ccc(Cl)cc1 +CC(NC(=O)C1CCC(=O)N1)c1cccc(F)c1 +Cc1ccc2oc(=O)cc(CN3CC(C)OC(C)C3)c2c1 +CC(OC(=O)c1ccc(Cl)cc1N)c1nc2ccccc2c(=O)[nH]1 +NC(=O)N1CCOCC2(CCC(CNC(=O)c3cnccn3)O2)C1 +CN(C)S(=O)(=O)CC(=O)NC1CC1c1cccc(F)c1 +Cc1cc(C)c(C(=O)NC2CCCN(Cc3ccccc3)C2=O)o1 +CNC(=O)c1ccc(NCc2ccc(C)cc2)nc1 +COc1ccc(C(C)NC(=O)c2ccc3[nH]nnc3c2)cc1F +CCc1cc(C(=O)N2CCC(CS(N)(=O)=O)CC2)sc1C +Cc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccccc2)n1 +CCCn1nc(C)cc1NC(=O)c1cc(C)nc(N2CCCCC2)n1 +Cc1ccc(NC(=O)COn2nnc3ccc(Cl)cc32)cc1F +O=C(CCCn1nnc(-c2ccccc2)n1)c1ccc(F)cc1 +CC(C)(C)OC(=O)NCC1NCCc2c(F)ccc(F)c21 +COC(=O)c1ccc(CCC(=O)N(C)C(C)c2ccccn2)cc1 +CN(C(=O)c1ccc(Cl)cc1Cl)C1CCCCC1O +Cc1nscc1C(=O)NC1CCN(C(=O)Nc2ccccc2)CC1 +Nc1ccc(O)c(-c2n[nH]c(-c3cccc(F)c3)n2)c1 +O=C(NCCCc1cccc(F)c1)NCC1CN2CCCC2CO1 +CC(C)(C#N)c1ccccc1Cn1cc(CCO)cn1 +COc1cc(Cl)c(CNC(=O)c2ccc(Cl)cc2)cc1OC +OC(CCN1CCc2ccccc21)c1ccc(F)cc1 +CCCN(CC(=O)OCC)C(=O)c1cc(F)c(F)c(F)c1 +CC(C)C(NC(=O)C1CC1)c1ccc2c(c1)OCCCO2 +Cc1ccc(C(=O)CCC(=O)Nc2cc(C)ccc2O)cc1 +Cc1ccnc(NC(=O)C2CCN(c3ccc(C#N)cc3F)CC2)c1 +CCC(CC)NC(=O)c1ccc(NC(=O)C2CC2)cc1 +O=C(COc1ccc(F)cc1)Nc1cnn(-c2ccccc2F)c1 +CC1CC(C)CN(S(=O)(=O)N(C)Cc2ccccn2)C1 +CCOc1ccc(C(C)(C)C)cc1S(=O)(=O)Nc1ccncc1 +CC(C)CN(C)C(=O)Nc1ccccc1S(C)(=O)=O +CCNC(=O)c1cnn(-c2ccccc2)c1C(C)C +C#CCN1CCC(C(=O)Nc2ccc(C(C)=O)c(C)c2)CC1 +c1ccc(-n2nc(-c3cccnc3)c3c2CCNC3)nc1 +COc1ccc(Cc2n[nH]c(NCc3cccnc3)nc2=O)cc1 +CC1CCN(C(=O)CCC(=O)c2ccc(F)c(F)c2)CC1 +Cc1nnc2ccc(-c3cccc(C(F)(F)F)c3)nn12 +Cc1ccc(C(N)=O)cc1NC(=O)C1CC2CCC1C2 +CC(=O)c1cc2ccc3c(c2oc1=O)CN(Cc1cccnc1)CO3 +N#CC(C(=O)c1ccc(N2CCOC2=O)cc1)c1nc2ccccc2[nH]1 +COc1ccc(-c2ccc(C(=O)N3CCCCC3)cc2)cc1O +CCOC(C)c1nccn1CCOc1cc(C)ccc1C +CN(C)c1cc(F)c(C(=O)Nc2cccc(F)c2)cc1F +CCOC(=O)C(N)Cc1cc(C(C)C)c(O)cc1C +COC(=O)CCN(C)S(=O)(=O)N1CCCCC1C +Cc1nc(N2CCN(c3ccccc3)CC2)[nH]c(=O)c1CCO +O=C(NC(c1ccccn1)C(F)(F)F)c1c[nH]nc1-c1ccccc1 +O=c1[nH]c(NC2CCCCC2)nc2nccc(-c3ccccn3)c12 +O=C(COc1ccc(C(=O)c2ccccc2)cc1)NC1CC1 +CC(Cc1ccco1)NC(=O)Cc1csc(Cc2ccccc2)n1 +Cc1n[nH]c2ncc(C(=O)c3cc(F)ccc3O)cc12 +C#CCOc1ccc(C(=O)NCC(C)(C)c2ccncc2)cc1 +CC(C)N(C)C(=O)Cc1csc(NC(=O)c2ccccc2)n1 +CN(C(=O)c1cccc(F)c1)C1CCN(c2ccc(F)cc2)CC1 +O=C(Nc1ccc(O)cc1)c1cncc(Br)c1 +Cc1n[nH]cc1CNC(=O)c1sc2nc[nH]c(=O)c2c1C +CN(C)c1cccc(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)c1 +Cc1cccc(N2CCN(C(=O)NCCC(=O)OC(C)C)CC2)c1C +Cn1c(C2CC2)nc2cc(NC(=O)C3CCCc4[nH]ncc43)ccc21 +COCc1cc(C)nc(SCC(=O)NC(C)(C)C)c1C#N +CCCc1ccc(C(N)C(=O)NCCOC)cc1 +CC(=O)Nc1cccc(CN(CCC(N)=O)c2ccc(F)cc2)c1 +O=C(NCc1ccc(Cl)cc1)c1ccc2[nH]cnc2c1 +COc1ccc(CCN2CCCS2(=O)=O)cc1F +COc1ccc(OCCCC(=O)Nc2ccc3nc(C)oc3c2)cc1 +CC(C)N(C(=O)c1cnn(-c2ccc(F)cc2)n1)c1ccccc1 +Cc1noc(C2CN(C(=O)Cc3cccs3)C2)n1 +O=C(NCCN1CCOCC1)C1CC(=O)N(C2CCCC2)C1 +CCN(C)C(C(=O)NCC(C)(C)c1ccncc1)c1ccccc1 +CC(C(=O)Nc1nccs1)c1ccc(CC2CCCC2=O)cc1 +O=C(Nc1c[nH]cc(Br)c1=O)c1noc2c1CCCC2 +CS(=O)(=O)N1CCN(C(=O)COCc2ccccc2)CC1 +Cc1cc2cc(CCNC(=O)C3CCCCC3)c(=O)[nH]c2cc1C +COc1ccc(N(C)C(=O)c2ccc(OCC(F)F)nc2)cc1F +COc1ccc(C)c2c1N(C(=O)CCc1c(C)nn(C)c1C)CCC2 +CC(=O)c1sc(CS(=O)(=O)c2ccc(C)cc2)nc1C +CC(Sc1ccc(Cl)cc1)C(=O)N(C)CC(=O)N(C)C +CCc1nnnn1CC(=O)NCCc1ccc(F)cc1 +Cc1cc(NC(=O)CSc2nc(C)c(C)n2CC(C)C)no1 +Cc1ccc(NC(=O)NCCC2CC2)cc1S(C)(=O)=O +COC(=O)C1CCc2ccccc2N1C(=O)c1ccco1 +CCCCn1nc(C(=O)Nc2nnc(CC)s2)ccc1=O +CC(C)CCSc1nc2c(c(=O)[nH]c(=O)n2C)n1C(C)C +N#Cc1ccc(F)c(CSc2nncs2)c1 +CCCOc1ccc(C(=O)Nc2nnnn2CC)cc1 +CN1C(c2ccccc2)CC(=O)CC1c1ccccc1 +OCc1cc(-c2ccc(OCC3CCCO3)cc2)on1 +Cc1c2cn[nH]c(=O)c2c(C)n1Cc1ccccc1F +COc1ccc(NC(=O)c2ccc(C)o2)cc1OC1CCCC1 +Cc1cccc(COC(=O)C(Cc2ccccc2)NC(N)=O)c1 +Cc1nnc(SCC(=O)Nc2cccc3ccccc23)s1 +Cc1cc(C)c2c(c1)C(C#N)(N1CCCC1)CCCO2 +CC(C(=O)Nc1c(-c2ccc(F)cc2)ncn1C)c1cccs1 +O=C(c1ccc(N2CCOCC2)nc1)N1CCOC2CCCCC21 +CCNC(=O)NCCC1CN(Cc2ccc3nonc3c2)CCO1 +CCN(CCC(=O)OC)C(=O)c1ccccc1C(F)(F)F +CN(C)C(=O)c1cccc(OC(=O)CCNC(=O)C(C)(C)C)c1 +CCc1nc2n(n1)CC(C(=O)Nc1ccc(C)c(Cl)c1)=C(C)N2 +c1ccc(-c2noc(Cn3ccc(C4CC4)n3)n2)cc1 +CCCC(=O)N1CCN(CC(=O)NCCOC)CC1 +CCCNC(=O)c1cc(-c2ccccn2)nc2ccc(C)cc12 +COC(=O)c1cc(S(=O)(=O)Nc2cc(C)cc(C)c2)cn1C +COC(=O)C1=C(N)c2c(F)cccc2C(C#N)(c2ccccc2)C1 +O=C(C1COCCO1)N(Cc1ccc(F)cc1)CC1CC1 +COC(=O)COc1cccc(NC(=O)Cc2cccs2)c1 +CCCC(=O)Nc1cc2c3c(c1)CC(=O)N3CCC2 +O=C(Nn1cnc2ccccc21)c1ccc(F)cc1 +CC(=O)Nc1ccc(C)c(NC(=O)NC(C(N)=O)C(C)C)c1 +CCCCCNC(=O)Nc1cccc(N2CCOC2=O)c1 +Cc1cc(SCC(=O)c2ccc(O)cc2O)ncn1 +Cc1nc(-c2ncccn2)sc1C(=O)NC(C)(CC(C)C)C(N)=O +COc1ccccc1C(C)N(C)C(=O)CNC(=O)CC1CCCCC1 +CC(=O)N1CCN(CC(=O)N2CCOC(c3ccc(F)cc3)C2)CC1 +CCn1cc(NCc2c(C)nc3scc(C)n23)cn1 +CC1CN(CC(=O)NC(C)(C#N)C(C)C)CC(C)O1 +CCNC(=O)N1CCn2nc(-c3nc4ccc(OC)cc4[nH]3)cc2C1 +CC(C)CN(C)C(=O)CCNS(=O)(=O)c1ccccc1 +COc1ccc(-c2cc(C(=O)Nc3ccc(Cl)cn3)no2)cc1 +Cn1ncc(NCCNc2ncccc2C(F)(F)F)c(Cl)c1=O +CCCC(=O)N1CCc2nc(NC(=O)c3cc(C)on3)sc2C1 +CCc1nn(C)c(OC)c1CN1CCN(C(=O)C2CCCCC2)CC1 +CC(C)(C)NS(=O)(=O)c1ccc(C#CCO)cc1Cl +Cc1ccccc1CNC(=O)CCC(=O)Nc1nccs1 +CCn1ccc2c(cc(C(=O)Nc3cccc(Cl)c3C)n2C)c1=O +Cc1noc(COC2CCN(C(=O)Cc3ccsc3)CC2)n1 +CN(Cc1cnn(C)c1)C(=O)c1sccc1C1CC1 +O=C(NC1CCOCC1)c1ccc(NCCOc2ccccc2)cc1 +O=C(Nc1ccc(-n2ccnc2)nc1)c1ccccc1Cl +CC(c1ccccc1)N1Cc2nc(N3CCCC3)ncc2C1=O +CCN(Cc1scnc1C)C(C)c1cccc(O)c1 +Cc1ccsc1CN(C)C(=O)C(C)OCC(C)C +COc1ccc(C(=O)NCc2nnnn2C2CCCCC2)c(OC)c1 +COc1ccc(CC(O)Cc2ccncc2)cc1Br +CN(C(=O)c1ccnc(OCC(F)F)c1)c1ccc(Cl)cn1 +O=C(Nc1ccccc1)C1CCCN(C(=O)c2n[nH]c3ccccc23)C1 +Nc1ccc(C(=O)N2CCN(S(N)(=O)=O)CC2)cc1 +O=C(CCc1nc2ncccc2[nH]1)NCc1ccc2c(c1)OCO2 +Cc1cccc(N2CC(C)N(Cc3nc4ccccc4[nH]3)CC2=O)c1 +CC1CC(N2CCOC(CN(C)c3cccnn3)C2)C(=O)O1 +Cc1nc(-c2ccc(CNC(=O)c3ccoc3)cc2)cs1 +CCN(Cc1ccccc1NC(=O)NC(C)C)C(=O)OC(C)(C)C +CC(=O)Nc1ccc(F)c(NCC(=O)Nc2ccc(C(N)=O)cc2)c1 +CCOC(=O)CCNc1c(Cl)cccc1Cl +CC12CCC(C(=O)Nc3ccc4c(c3)OCO4)(CC1=O)C2(C)C +Nc1cc2ncnc(Nc3cccc(Br)c3)c2cc1N +Cc1ccc(CN(C)C(=O)CSc2nc(N)c(C#N)cc2C#N)o1 +CCOc1ccc(C(=O)NCC(=O)Nc2nc(C(C)C)cs2)cc1 +O=c1cc(C2NCCc3ccc(Cl)c(Cl)c32)cc[nH]1 +CC(=O)N(Cc1cc2ccccc2[nH]c1=O)C(C)C +COc1cccc(C(=O)N2CCC(C)C2C)c1F +Cc1ccccc1-n1nccc1NC(=O)C1CC=CC1 +N#Cc1ccc(S(=O)(=O)Oc2ccccc2C#N)cc1 +Cc1ccc(NC(=O)CCNC(N)=O)c(OCC(F)(F)F)c1 +CCn1nc(C(=O)Nc2nnc(C)s2)c(=O)c2cc(F)ccc21 +Cc1occc(=O)c1OCC(=O)Nc1ccc(Br)cc1 +COCn1c(Cc2cccs2)nc2c(N)cccc21 +CC(C)COCCNC(=O)N1CCc2cc(F)ccc2C1 +CCOc1ccccc1NC(=O)C1CC(=O)N(C)C1 +CC(C)(C)Nc1ncnc(Nc2cccnc2)c1N +CN(C)c1ccc(S(=O)(=O)N(C)C)cc1NC(N)=O +Cc1nn(C)c(C)c1CNCC(C)(C)c1ccccc1 +CN(C(=O)Cc1cccs1)c1nnc(-c2cccnc2)s1 +COCCNC(=O)Nc1ccc2c(c1)C(=O)N(C)CCO2 +COC1CCC(OC(=O)c2cn(C)nc2C(C)(C)C)CC1 +COCCN1CC(C(=O)N(C)c2ccc(F)c(F)c2)CC1=O +CCc1nc(NC(=O)CN(C)CC(C)C#N)sc1C +Cc1nc(-c2cnccn2)nc2c1CCC(=O)N2Cc1cccnc1 +COc1cc(C(C)Nc2cccnc2)ccc1SC +Cc1csc(C2CN(CC3(O)CCCCC3)CCO2)n1 +Cc1ccc(N)cc1NC(=O)c1ccc(F)c(F)c1F +COc1ccc(C(=O)NC2CCC(C)CC2)cc1OCCO +CC(C)Cn1nc(-c2ccc(F)cc2)cc(C(C)(C)O)c1=O +COc1ccc(CC(=O)Nc2cnn(CCc3ccccc3)c2)cc1 +COc1ccc(-c2noc(C(C)Sc3nncn3C)n2)cc1OC +CC(C)(C)c1ccc(C(=O)Nc2ccccn2)c(N)n1 +CCN(CCO)C(=O)c1n[nH]c(=O)c2ccccc12 +CC(=O)c1ccc(NC(=O)c2csc(Nc3ccccn3)n2)cc1 +CC(C)c1ccc(CCN(C)C(=O)CCCO)cc1 +Cc1ccc(N(C)C(=O)c2ccc(N)cc2)c(C)c1 +O=C(c1cscn1)N1CCC2(CCCCC2)C1 +Cc1ccc(N)c2ccnc(C(=O)Nc3ccccc3F)c12 +CC(C)OCCCNC(=O)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +COCC1CCC2C(CCN2S(=O)(=O)c2ccccc2)O1 +CCN(C)c1ccc(C(=O)Nc2cc(F)ccc2OC)cc1 +COc1ncccc1CNC(=O)COc1ccc(F)c(F)c1 +CCNC(=O)Cn1nnc(-c2ccc(F)c(C)c2)n1 +CCOC(=O)CN(Cc1ccc(F)cc1)C(=O)CC +Cc1ccccc1C1(CNC(=O)C(C)NC(N)=O)CCOCC1 +CN(Cc1ccc(C#N)cc1)C1=NS(=O)(=O)c2ccccc21 +CCSc1ccc(C(=O)Nc2nc(C)c(C)s2)cc1 +CNC(=O)c1cc(NC(=O)NCC(=O)NC(C)(C)C)ccc1Cl +CC(C)CN(CC(C)C)C(=O)CN1CCN(c2ccccc2O)CC1 +C=CCn1cc(CN2CCN(Cc3ccccc3F)C(=O)C2)c(C)n1 +Cc1cc(=O)n(CC(=O)N(Cc2ccccc2)Cc2ccccc2)cn1 +COc1ccc(-c2c(CC(C)C)noc2N)cc1OC +CC(=O)c1ccc(NC(=O)c2cscn2)cc1C +Cc1ccc(-c2nnc(CNC(=O)c3cccc(F)c3F)o2)s1 +O=C(CCSc1ccccc1)NCc1cccc(-n2cncn2)c1 +CC1CN(C(=O)CCc2c[nH]c3ccccc23)CC1N1CCOCC1 +CCC1CCC(NC(=O)NCCN2CCOCC2)CC1 +Cc1cc(NCc2ccco2)cc(=O)n1Cc1cccnc1 +O=C(c1ccccn1)N1CCCC1c1nc2ccccc2s1 +CC(CC(=O)N1CC(n2cncn2)C1)NC(=O)c1ccccc1 +CCc1ccccc1CNC(=O)NCC(O)c1c(F)cccc1F +Cc1ccc2c(c1)CC(=O)N2CC(=O)NCc1ccc(F)cc1 +O=C(CN1CCOC(Cn2cncn2)C1)Nc1cccnc1 +CC(NC(=O)C(Cc1ccccc1)NC(N)=O)c1ccccc1 +CCCSc1ccccc1C(=O)N1CC(C)OC(C)C1 +CS(=O)(=O)c1ccc(NC(=O)c2cnc3ccccc3n2)cc1 +CS(=O)(=O)c1ccc(NC(=O)C2CCCO2)cc1 +Cc1ccc(C)c(CN2CC(c3nc(-c4cccnc4)no3)C2)c1 +COc1cc(C(=O)Nc2nc(C(C)=O)cs2)cc(Cl)c1OC +CCc1ccc(CNc2ccc3[nH]nc(C(N)=O)c3c2)o1 +COCCNC(=O)c1ccc(-c2ccc(C(C)=O)cc2)o1 +CSc1ccc(C)c(C(=O)N2CCCC2C(=O)N2CCOCC2)c1 +O=C(Nc1nnc(C2CCCCC2)o1)C1CCCC1 +CC(C)(NC(=O)c1ccc(F)nc1)c1ccc(Cl)cc1 +Cc1nsc(NC(=O)N(C)Cc2cccc(-n3cccn3)c2)n1 +CCOc1ccccc1CNC(=O)c1cccc(C#N)c1 +CCOc1cc(F)ccc1NC(=O)C1CCN(C(=O)C(C)C)CC1 +Cc1nc(NC(=O)NCC2(O)CCOCC2)sc1C +Cc1cc(NC(=O)NC(C)(CO)C2CC2)ccc1OC1CCOCC1 +CCOCC1CCCN1C(=O)c1ccc(C(C)C)[nH]c1=O +CC(=O)c1cc(C(=O)NCc2c[nH]nc2C)n(C)c1 +O=C(Nc1ccccc1)c1cnc2ccccn2c1=O +CC(NC(=O)C1(c2cccc(F)c2)CCCCC1)C(N)=O +N#Cc1ccccc1NC(=O)Cc1ccc(F)c(F)c1 +O=C(c1c[nH]cn1)N1CCc2nnc(Cn3cccn3)n2CC1 +CCN(CC)c1nc2c(s1)C(=O)CC(C)(C)C2 +CCC1C(=O)Nc2c(C)cc(C(O)C(C)(C)C)cc21 +Nc1ccc2c(c1)CCN2C(=O)c1ccc(Br)cc1 +COC(=O)c1ccc(C(=O)NCCNC(C)=O)cc1 +C=CCNC(=O)c1cc(NC(=O)C2CCCC2)n(C)n1 +CC1CCC(N(C)C(=O)CNc2ccc(C(N)=O)cc2)CC1 +CCc1nnc(Nc2cc(C)nc3nc(C)ccc23)s1 +O=C(NC1CC2CC1C1CCCC21)c1ccc(C(F)(F)F)nc1 +Cc1ccc(S(=O)(=O)Nc2ccccc2O)cc1 +COc1ccccc1-c1cc(C(C)=O)cc(OC)c1OC +CCOc1ccccc1NC(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +COCCn1nc(-c2cccs2)cc(C#N)c1=O +Cc1nc2sc3c(c2c2nc(Cc4ccccc4)nn12)CCN(C)C3 +CCn1cc(Cl)c(C(=O)N2CCN(c3ccccc3OC)CC2)n1 +CCn1c(SCC(=O)NC(C)C)nnc1-c1ccc(Cl)cc1 +c1ccc(-c2nn3c(CN4CCOCC4)nnc3s2)nc1 +CC(=O)Nc1nc(CSc2nnc3cc(C)nc(C)n23)cs1 +COc1ccc(CCNC(=O)c2c(C)c(C)nn(C)c2=O)cc1OC +Cc1nnc2c(NCCC(C)C)nc3ccccc3n12 +CC1Cc2ccccc2C1NC(=O)CNC(=O)c1ccsc1 +O=C(CC1CCCO1)Nc1cnc2ccccc2n1 +CCOc1ncccc1NC(=O)NC1CCN(S(C)(=O)=O)CC1 +O=C(Nc1ccccc1)c1cccc(-n2ccnc2)n1 +CCC(C)n1nccc1NC(=O)c1ccc(OC)c(OC(F)F)c1 +O=C(CCCn1cccc1)Nc1cc(Cl)ccc1O +Cc1cc(C)n(-c2ccc(=O)n(CC(=O)N3CCCC3)n2)n1 +CC(=O)Oc1ccc2nc(-c3ccccc3C)oc(=O)c2c1 +Cc1c(NC(C)C(C)C)cccc1C(=O)Nc1nc[nH]n1 +COc1ccc(CNC(=O)NC(C)CO)c(OC)c1 +Cc1cc(S(=O)(=O)NCc2ccccn2)ccc1Cl +CNS(=O)(=O)c1ccc(C(=O)N(C)CCC(F)(F)F)cc1 +Cc1cc(C2CCCCN2C(=O)C2CCN(C(=O)C3CC3)CC2)no1 +CCOc1cccc(NC(=O)CCc2c(C)n[nH]c2C)c1 +CC(C(=O)NC(C)(C#N)CCc1ccccc1)N1CCCCC1=O +C=CCN(CCO)S(=O)(=O)c1cccc(F)c1C +O=C(NCC(O)c1c(F)cccc1F)Nc1ccc2c(c1)COC2 +COCC(C)NC(=O)CCc1ccc(OC)cc1 +O=C(c1c[nH]c2ccccc12)N1CCC(Cn2cccn2)CC1 +C=CCn1c(SC2CCN(C)C2=O)nc2ccccc2c1=O +CC(NC(=O)Nc1ccc2c(c1)OCO2)C1CCCO1 +Cc1cccc(CNC(=O)Nc2cnn(Cc3ccccc3)c2)c1 +CC1CN(CCCCNC(=O)c2cc(C(C)C)nn2C)CC(C)O1 +c1ccc(-n2ccc(CN3CCc4cncnc4C3)n2)cc1 +COC(=O)c1ccc(CNC(C)C(=O)OC)cc1 +COC(=O)c1nc(C)sc1-c1c(F)cccc1Cl +CCCC(Nc1cc(C(C)C)nc(N)n1)C(=O)NC +CC(C(=O)Nc1ccc(F)cc1N)n1cc(Br)cn1 +O=C(NCCS(=O)(=O)N1CCOCC1)c1n[nH]c2ccccc12 +CCCC(C)N1CC(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)CC1=O +CN(Cc1csc(-c2cccs2)n1)C(=O)C1CCOC1 +Cc1ccccc1C1CCCN(C(=O)c2cnc(C(C)C)nc2C)C1 +OCC#Cc1ccccc1OCc1ccc(F)cc1 +COCCOc1cccc(C(=O)Nc2cnn(C)c2)c1 +O=C(NCC1COc2ccccc2O1)c1ccc(=O)[nH]c1 +O=C(CSc1ccc(F)c(F)c1)NCCc1cccs1 +CC(Nc1ncccc1C#N)C(=O)NCC(F)(F)F +CC1CCC(C#N)(N2CCC3(CC2)OCCO3)CC1 +O=C(OCc1cc(-c2ccco2)on1)C1CCCC1 +Cc1ccc(OCC(=O)N(CCC(N)=O)c2ccccc2)c(C)c1 +Fc1ccc(-c2csc(NCc3ccco3)n2)cc1 +CCOC(=O)c1nnsc1NC(=O)c1cc(C)no1 +Cc1nccn1-c1ccc(CNC(=O)c2ccc(O)c(Cl)c2)cn1 +O=C(c1cc(C2CC2)nc2ccccc12)N1CCOCC(CO)C1 +COc1c(O)ccc2c1C(c1ccc(O)c(F)c1)NCC2 +CCCn1ncc(-c2nc(-c3ccncc3)no2)c1C +CN(Cc1nnc2ccccn12)C(=O)c1cc2ccccc2[nH]1 +Cc1nc(C)c(-c2nnc(NC(=O)c3ccc(N(C)C)cc3)o2)s1 +Cc1c(C)c2ccc(NC(=O)c3cccnc3)cc2[nH]c1=O +Cc1noc(C)c1CNS(=O)(=O)c1ccccc1C(F)(F)F +CN(CC(=O)NC1CCC(O)CC1)c1ccccc1 +O=C(CO)N1CCN(C(=O)c2ccc(Oc3ccccc3)cc2)CC1 +COC(=O)C1CCN(S(=O)(=O)c2ccccc2)CC1 +O=C(Nc1nc(C(=O)Nc2ccc(F)cc2F)co1)c1cnccn1 +Nc1c(NCC2CCCO2)ncnc1Nc1ccc(F)c(F)c1 +COCCNC(=O)c1cc2ncc(Br)cn2n1 +COc1ccc(C#CCNC(=O)c2cnn(-c3ccccc3)c2C)cc1 +COc1ccc(C(N)=O)cc1S(=O)(=O)N(C)Cc1ccccc1 +COCCN1CC(C(=O)Nc2cccc(-c3nccs3)c2)CC1=O +CCNC(=O)CCCc1nc(-c2ccc(C)c(F)c2)no1 +O=C(Nc1cccnc1)C1COCC2CN(c3ccncn3)CC21 +COc1ccc(NC(=O)Cc2ccc[nH]2)cc1-n1nnnc1C +Cn1nc(C(C)(C)C)cc1C(=O)Nc1ccccc1-n1cccn1 +CC(=O)NC1CCCN(C(=O)NCC2Cc3ccccc3O2)C1 +CC(CC(=O)Nc1nc(C(C)(C)C)cs1)n1cncn1 +Cc1cnn(CCC(=O)N2CCOC(c3nc(C(C)C)n[nH]3)C2)c1 +N#Cc1cccc(NC(=O)COC(=O)c2nccc3ccccc23)c1 +Cc1nc(C2CCCN(C(=O)c3ncc(F)cc3F)C2)cc(=O)[nH]1 +Cc1cc(OC(=O)c2cc(C(N)=O)cs2)ccc1Cl +Cc1ccsc1CCNC(=O)c1cnc(N2CCCC2)nc1 +CN(Cc1nccn1C(F)F)S(=O)(=O)c1ccc(Cl)cc1 +CCCc1c(CC)nn(-c2nc(C)cc(C)n2)c1N +O=C(Nc1ccc(OC(F)F)cc1OC(F)F)c1ccncc1 +Cc1csc(NC(=O)N2CCN(C(=O)c3ccoc3)CC2)n1 +CCOC(=O)c1nsc(C(=O)NCCOC)c1N +Cc1ccc(-n2nc3c(nc2=O)[nH]c2ccccc23)cc1 +O=S(=O)(c1cccc(F)c1)N1CCCC1c1nc(C2CC2)no1 +CCOc1ccccc1NC(=O)n1ncc2ccccc21 +Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)N1CC(C)CC(C)C1 +CC(NC(=O)CNC(N)=O)c1ccc(F)c(Cl)c1 +CC(C)COC(=O)N1CCC(C(=O)Nc2ccc(F)c(C#N)c2)CC1 +COc1cc(C#N)ccc1CNc1cncnc1C +Cn1nccc1-c1nnc(NC(=O)c2ccc(F)c(F)c2)o1 +COCC(C)C(=O)N(Cc1ccccc1)c1ccncc1 +CC(C)COc1ncc(CNC(=O)c2sccc2C#N)cc1Cl +Cc1cccc(NC(=O)NCc2ccc(C(=O)N(C)C)cc2)c1C +O=C(CCC(=O)c1ccccc1)NCc1ccccc1Cl +CCc1noc(CN(C)Cc2cnc(C3CCC3)s2)n1 +CN(Cc1cnn(C)c1)C(=O)CCc1ccc(S(N)(=O)=O)cc1 +COc1ccccc1C1CSc2nnc(C)n2N1 +Cc1nc(-c2ccccc2)sc1C(=O)N1CCOC(C)(C)C1 +Nc1cccn2c(Cc3ccc(Cl)cc3)nnc12 +CCCn1ncc(C(=O)NC(C)C(=O)Nc2ccc(F)cc2C)c1C +Fc1cccc(CSc2nnnn2-c2ccc3c(c2)OCO3)c1 +COc1ccc(C(F)(F)C(F)(F)F)cc1OC +COc1ccccc1C(C)NC(=O)c1cnccn1 +CC(C)OCCC(=O)N1CCCCC1C(=O)NC(C)(C)C +CC(C)NC(=O)Nc1ccc(C(=O)N=c2sccn2C)cc1 +O=C1CCN(CCOc2ccc(-c3ccccc3)cc2)CC1 +CCNC(=O)C(C)NC(=O)c1ccccc1-c1nc(C(C)(C)C)no1 +CCn1c(NCCCO)nc2c1c(=O)[nH]c(=O)n2CC +CCCC(C)(O)C(=O)NC(C)C(O)c1ccc(OC)cc1 +Cc1nc2cc(C(=O)NCCS(=O)(=O)N3CCCC3)ccc2[nH]1 +COC(=O)c1cccn2cc(COc3ccccc3F)nc12 +Cc1nn(CC(=O)Nc2ccccc2F)c(=O)c2noc(C)c12 +CCc1ccccc1NC1=Nc2cc(N)ccc2OC1 +CN(C)C(=O)c1ccc(Cl)c(NC(=O)NC(C)(C)CO)c1 +CCN(C(=O)c1cc(N)c(OC)c(OC)c1)c1ccccc1 +Cc1ccnc(C(NC(=O)c2cncc(F)c2)C2CC2)n1 +COC(=O)C1CCN(C(=O)CCSc2ccc(Cl)cc2)CC1 +CCC(CC)N(CCO)C(=O)Cc1c(C)noc1C +COc1ccc(C(=O)Nc2ccc(C(C)=O)c(C)c2)cc1OC +O=C(c1cccc(Br)c1)N1CCCCC1CO +O=C(CCc1nnc(-c2ccsc2)o1)NCC1CCCC1 +CCc1ccc(CCNC(=O)CSc2nc(C)n[nH]2)cc1 +CC(C)N(CC(F)(F)F)C(=O)Cn1nccc1-c1ccncc1 +O=C(CC1C=CCC1)NCc1cnn(Cc2ccccc2)c1 +O=C(Nn1cnnc1)C1CCN(c2ccccc2)CC1 +COc1ccc(CN(C)C(=O)CN2CCN(CCO)CC2)cc1 +Nc1cnc(Cc2ccc(Cl)cc2Cl)nc1 +COC(=O)c1ccc(NCc2csc(C3CCCO3)n2)c(F)c1 +Cc1nc(C(=O)N2CCCCC2)cc(N2CC(C)CC(C)C2)n1 +COC1CCN(C(=O)N2CCCC2)CC1Cc1ccccc1 +CC(C)(C)OC(=O)NS(=O)(=O)Nc1cccnc1 +O=C(CCCNC(=O)c1cccs1)Nc1ccccc1 +Cc1ccc(CCNC(=O)c2ccc(-n3ccnn3)cc2)cn1 +Cn1c(=O)n(C2CCN(C(=O)c3ccco3)C2)c2ncncc21 +CCOC(=O)C1=C(CN2CCCCC2)NC(=O)NC1c1ccccc1 +NC(=O)CCCNC(=O)NCCc1ccccc1Cl +Cc1ccc(NC(=O)C2CC(=O)N(C)C2)c(OCC2CCCO2)c1 +COc1ccc(C)cc1C(O)CN1CCN(c2nccs2)CC1 +CCCN1C(=O)NC(c2ccc(O)c(OC)c2)C(C(=O)OC)=C1C +NC(=O)CN(Cc1ccccc1)C(=O)c1cccc(-c2ccoc2)c1 +CC1CCC2C(CCCN2C(=O)c2cccc3[nH]ncc23)C1 +Cc1nc(C)n(-c2ccccc2NC(=O)c2cscc2C)n1 +Cc1cccc(OCCc2nnc(NC(=O)C(C)C)s2)c1C +O=C(Nc1cnn(-c2ncc(N3CCCCC3)cn2)c1)C1CCCO1 +CCS(=O)(=O)NCC(=O)NC(c1ccccc1F)C1CCCC1 +CC(CNC(=O)c1cc(Br)c[nH]1)N1CCOCC1 +COCCN(Cc1ccc(C)o1)C(=O)N=c1[nH]nc2ccccn12 +Cc1cscc1C(=O)Nc1cc(Br)c(=O)n(C)c1 +Nc1cc(F)c(F)cc1NC(=O)c1cccc(F)c1 +CCOC(=O)c1c(NC(=O)NC(C)C)sc2c1CCCC2 +CC(=O)c1cccc(NC(=O)N2CCC(C(N)=O)C2)c1 +Cc1ncc2c(n1)CN(Cc1nn(-c3ccccc3)c3c1CCC3)CC2 +COCC(O)CN(C)C(=O)COc1ccc(C)cc1 +CN(C)C(=O)C1CCCN1C(=O)c1cnc(-c2ccccc2)s1 +NS(=O)(=O)c1ccc(CCNC(=O)N2CCC2)cc1 +COc1ccccc1NCC(=O)c1cc(F)ccc1F +COc1cc(OC)cc(C(=O)N2CCN(Cc3ccccn3)CC2)c1 +COc1ccc(CCNC(=O)COc2nnc3ccccn23)cc1 +CCC(C)C(C)NC(=O)c1cccc(-n2cnnn2)c1 +Cc1cc(NC(=O)CNC(=O)CC23CC4CC(CC(C4)C2)C3)[nH]n1 +COc1ccc(-c2ccc(OC)c3nc(N)nn23)cc1OC +CC(C)c1csc(NC(=O)c2ccc(NC(=O)C3CC3)cc2)n1 +CCOC(=O)N1CCN(Cc2cc(=O)oc3cc(OC)ccc23)CC1 +Nc1nc(SCC(=O)Nc2ccc(Cl)cn2)n[nH]1 +Cc1nn(C(C)C)c(C)c1NC(=O)c1n[nH]c(N)n1 +CCCCNC(=O)N(CCO)Cc1ccccc1 +Cc1nnc2n1CCN(C(=O)c1cnc(C3CC3)s1)C2 +CCn1nc(C)c(NC(=O)c2c(F)cccc2F)c1C +CC(NC(=O)c1ccc(CNC(N)=O)cc1)c1ccncc1 +CNC(=O)N1CCC2(CC1)C(=O)N(C)c1ccc(F)cc12 +COc1ccc(CCC(=O)NCc2cscn2)cc1 +COc1ccc(C)cc1CC(=O)Nc1cccc(F)c1 +O=C1CCCc2c1c(C(F)(F)F)nn2Cc1ccccc1 +FC(F)(F)c1cc(NCc2csc(C3CC3)n2)n2ncnc2n1 +Cc1cccc(Nc2nc(-c3ccc(O)cc3)cs2)n1 +CCOC(CC)C(=O)NCc1ccccc1Cl +O=C(NCCc1cn2ccccc2n1)c1ccc(F)c(F)c1 +C=CCN1C(=O)C2(NCCc3c2[nH]c2ccc(F)cc32)c2ccccc21 +Cc1nc(CNC(=O)NCC(C)N2CC(C)OC(C)C2)cs1 +CC(C)(C)c1cc(C(=O)OCCNC(=O)c2ccncc2)[nH]n1 +N#Cc1c(Nc2ccc(Cl)cc2)nc(N)[nH]c1=O +CC(C)Cn1ncc(C(=O)Nc2ccc(F)c(F)c2F)c1C1CC1 +CC(C)c1nc(C2CCN(C(=O)Nc3ccccc3)CC2)no1 +N#Cc1c(Cl)cccc1NCCN1CCOCC1 +CC(C(=O)NCCc1cccs1)N(C)CCC#N +C=CCOC(=O)c1ccccc1NC(=O)c1ccsc1 +CCNC(=O)CCN1CCOC(c2ccc(C(F)(F)F)cc2)C1 +Cc1cc(F)ccc1NC(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +O=C(C1CCCCC1)N1CCN(c2ccc(-n3cccn3)nn2)CC1 +C=CCNS(=O)(=O)c1ccc(Br)c(C)c1 +COc1cc(OC)c(NC(=O)c2cccc3c2ccn3C)cc1F +CSc1ccc(C(=O)Nc2nnc(Cc3ccc(C)cc3)o2)cc1 +COc1ccccc1NC(=O)CSc1nc(-c2ccccc2)n[nH]1 +CCc1ccc(OCC(O)Cn2cnc3sccc3c2=O)cc1 +Cc1cc2c(=O)n(CCC(=O)Nc3cccc(C#N)c3)cnc2s1 +Cn1cc(-c2ccc(C3CCN(C(=O)c4cccnc4)CC3)nc2)cn1 +O=C(CCc1nc(-c2ccco2)no1)NCC1CCCO1 +Cc1nc(-c2ccccc2)sc1NC(=O)NC(C)CO +Cc1ccc(-c2nnc(-c3cccnc3)o2)c(C)c1 +Cn1nc(C(F)(F)F)cc1C(=O)Nc1ccccc1C(N)=O +O=C(NCc1cccs1)c1ccc(N2CCCS2(=O)=O)cc1 +Cc1oc(C(C)C)cc1C(=O)N1CCN2CCN(C)C(=O)C2C1 +CCc1nc(CN2CCN(C(=O)CCN3CCCC3=O)CC2)no1 +CCC(NC(=O)N(C)Cc1c(C)noc1C)c1cccc(Cl)c1 +CCOc1ccc(-c2nc(C(=O)N3CCC(C(N)=O)C3)cs2)cc1 +CC1CCC(C(N)=O)CN1C(=O)c1ccc(-n2ccnn2)cc1 +CCOc1ccc(S(=O)(=O)Nc2cccc(C)n2)c(C)c1C +CCOc1ccccc1-c1nnc(SCC(=O)C2=NC=CC2)o1 +CC(=O)Nc1cccc(Nc2ncccc2CO)c1 +CCC1CCCCN1c1ncnc(N2CCC(C)CC2)c1N +Cc1noc(CCCC(=O)NC(c2ccc(F)cc2)C2CCCO2)n1 +CCOc1cccc(C(C#N)N(C)C(=O)c2ccccc2)c1 +CC(O)CC1COCCN1C(=O)NC1CC(C)(C)c2ccccc21 +COc1ccc(OC)c(CC(=O)N2CCC(O)CC2)c1 +O=C(CCc1ccco1)NC(c1ccc(F)cc1)C1CCCO1 +Cc1ccc(C)c(OC(C)C(=O)NCCN2CCNC2=O)c1 +CCNC(=O)COc1ccccc1NC(=O)C1CC1 +COc1ccc(S(=O)(=O)NCCNC(=O)C2CNC(=O)C2)cc1 +CCC(CO)NC(=O)NCc1ccc(C)cc1C +CC(=O)N1CCCN(C(=O)CCn2cnc3ccccc3c2=O)CC1 +O=C(C1CCC2(CCN(Cc3nccs3)CC2)CO1)N1CCCC1 +Cn1c(=O)ccn(CC(=O)NCC(C)(C)N2CCOCC2)c1=O +CCC(=O)N1CCN(c2ccc(C(=O)OC)cc2N)CC1 +Cc1nnnn1-c1cccc(NC(=O)c2ccccc2C(F)(F)F)c1 +Cn1cnc2c1c(=O)n(Cc1nc(C(C)(C)C)no1)c(=O)n2C +CN(C)c1cc(C(=O)Nc2cc(Cl)ccc2Cl)ccn1 +Cc1nnc(SCC(=O)Nc2cc(Cl)ccc2Cl)s1 +COCC(=O)Nc1ccc(Oc2ccc(S(N)(=O)=O)cc2)cc1 +c1ccc(-c2cc(NCCCC3CCOC3)n3nccc3n2)cc1 +CCc1n[nH]c(SCC(=O)Nc2ccc(N3CCCCC3)nc2)n1 +Cc1ccc(S(=O)(=O)N(CCCO)C(C)(C)C)cc1C +Cc1c[nH]c(C(=O)N2CCN(C)C3(CCNC(=O)CC3)C2)c1 +CC1Cc2ccccc2N1S(=O)(=O)c1cn(C)c(=O)n(C)c1=O +Cc1cccc(NC(=O)C2CCCN2c2nccs2)c1 +Cc1cccc(NC(=O)c2nc(-c3cnccn3)no2)c1 +O=C(NCc1ccc(Cl)cc1)c1cc(-c2cccnc2)on1 +O=C(COC(=O)c1ccc2ccccc2n1)NCc1ccccc1 +CCC(C)NC(=O)CN1CCN(c2cccc(OC)c2)CC1 +COc1ccc(CN(C)C(=O)C(C)n2cncn2)cc1OC +O=C(COC(=O)c1ccc[nH]c1=O)NCc1ccccc1F +Cc1nc(N2CCCC2)ncc1C(=O)NCCCc1ccc(F)cc1 +CC(C)CNC(=O)c1cc(-n2ccnc2)ccc1F +COCCN(Cc1ccco1)C(=O)Cc1c(Cl)cccc1Cl +Cn1c(C(=O)Nc2ccc(Cn3cncn3)cc2)cc2cc(F)ccc21 +Cc1cc(C(=O)N2CCCCC2c2nc(-c3ccccc3)no2)on1 +CC1CN(c2ncc(Cl)cn2)CCN1C(=O)OC(C)(C)C +COc1c(NC(=O)Nc2cc(-c3ccccc3)ns2)c(C)nn1C +O=C(Nc1ccccc1)C(O)C(O)C(=O)Nc1ccccc1 +O=C(CCNC(=O)N1CCCC1C1CCCC1)NC1CCCC1 +Cc1cc(C)c(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)c(C)c1 +Cc1cnc2c(S(=O)(=O)N3CCCC3C(=O)N(C)C)cccc2c1 +CC1CCC(c2nnc(-c3ccc4c(c3)OCO4)o2)CC1 +Fc1ccc(-n2cc(CNCCc3cccs3)cn2)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)NCc1cnn(C)c1C +CCN(CC)C(=O)CCC(=O)NCc1scnc1C +COc1cc2c(cc1OC)CN(C(=O)C1CNC(=O)N1)CC2 +Cn1ccc2c(-c3ccc(C(N)=O)s3)ccnc21 +CCCn1nc(C(=O)Nc2ccnn2C(C)C)ccc1=O +Cc1ccc2ncc(C(=O)N3CC(C)(C)C3(C)C)n2c1 +COc1ccc(C(=O)CNC(=O)OC(C)(C)C)cc1OC +Nn1c(SCC(=O)Nc2ccccn2)nnc1-c1ccncc1 +CC(C)c1nc(CNCC(O)c2ccc3ccccc3c2)cs1 +Nc1ccc(Cl)c(-c2nn3c(C(F)(F)F)nnc3s2)c1 +CC(=O)c1cnc(NC(=O)Cn2c(C3CC3)nc3ccccc32)s1 +COC(=O)c1[nH]c2ccc(F)cc2c1NC(C)=O +C=CCOc1ccc(C(=O)N2CCC(Oc3ccccn3)CC2)cc1 +CCn1c(C2CCN(C(=O)OC(C)(C)C)CC2)n[nH]c1=O +COc1ccc(-c2nc(N)n(C(=O)c3ccco3)n2)cc1 +CCCNC(=O)CNC(=O)NCCC1CCCC1 +CCc1nc(CCNC(=O)N2CCCC2)sc1C +CCc1sc(C)cc1-c1nnc(NCCOC)s1 +Cc1noc2nc(C3CC3)cc(C(=O)OCC(=O)N(C)C)c12 +Cc1cc(C)c(NC(=O)COc2ccccn2)c(Cl)c1 +Cc1cc(=O)oc(C)c1C(=O)OCc1nnnn1-c1ccccc1 +O=C(Nc1ccc(Cl)cc1F)c1ccc(N2CCOCC2)nc1 +Cc1ccccc1-c1nnc(SCC(=O)NC(C)(C)C)n1C +OCc1ccc(Oc2ncnc3sccc23)cc1 +COc1ccc(OC)c(CSc2nc(N)c(C#N)cc2C#N)c1 +Cc1nc2cc(C(=O)NCc3ccncc3)ccc2n1C +Cc1cccc(OCc2nn3c(C(F)(F)F)nnc3s2)c1 +Cc1cc(F)ccc1S(=O)(=O)Nc1cccc(C)c1C(N)=O +CN(Cc1ccccc1F)C(=O)C1CC2CCC1O2 +Oc1cccc(OCCOc2ccc3c(c2)OCO3)c1 +O=C(NCCOc1cccnc1)N1CCCCC1c1cn[nH]c1 +Cc1ccnc2nc(C(=O)NCC34CC5CC(CC(C5)C3)C4)nn12 +CCN(C(=O)CCC(=O)c1ccc(F)c(N)c1)c1ccccc1 +CCCOCc1ccccc1CNc1c(C#N)c(=O)n(C)c(=O)n1C +COc1cccc2c1OCC(C(=O)NCc1c(C)noc1C)C2 +Cc1nn(CC(=O)N(C)C(C)c2ccc(F)cc2)c(=O)c(C#N)c1C +COCc1nc(CN2CCOC(C(C)C)C2)cs1 +C=CCNC(=O)CN1CCN(S(=O)(=O)c2ccccc2)CC1 +CCC(CC)C(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +CCS(=O)(=O)N1CCCC(C(=O)Nc2ccccc2C(C)C)C1 +CS(=O)(=O)c1ccc(F)c(NC(=O)CCc2ccccc2F)c1 +O=C(c1cc(-c2ccccc2)no1)N1CCOCC1C1CC1 +O=C(OCC(=O)c1c(O)cc(O)cc1O)c1ccccc1 +COc1ccc(C(=O)N(C)CC(=O)NC2CC2)cc1Br +CCc1ccc(C2COCCN2c2ccc3nnnn3n2)o1 +CC1CC1c1nnc(C2(c3ccc(Cl)cc3)CCOCC2)o1 +COc1cc(C#N)ccc1OS(=O)(=O)c1ccc(F)cc1C +Cc1csc(COc2ccc(Cl)cc2N)n1 +CCCOc1ccc(S(=O)(=O)n2nc(C)cc2C)cc1C +C=CCNC(=O)c1ccc2ccc(C(N)=O)cc2c1 +CCN1C(=O)C(C)(C(=O)NCCCO)Oc2ccccc21 +CC(C)n1nc(-c2ccccc2F)c2c1CCCC2CC#N +COc1cccc(-c2nc(-c3ccc(C)nn3)no2)c1O +O=C(NCCSc1ccc(Cl)cc1)c1cn2cccnc2n1 +Cc1ccc(NC(=O)C2CC2)cc1NC1CCN(C)C1=O +CCOc1ccc(-c2cc(C#N)c(=O)n(CC)n2)cc1Cl +CCN(CC(=O)Nc1cnn(CC)c1)c1ccccc1 +CC(=O)Nc1cccc(-c2n[nH]c(-c3cccc(N)c3)n2)c1 +CC1CC(C)CN(C(=O)Nc2ccc(C(N)=O)cc2)C1 +CC(OCc1ccccc1)n1cc(Nc2ccccc2)c(=O)[nH]c1=O +CCCNS(=O)(=O)c1ccc(-c2ccc(=O)[nH]n2)o1 +CNc1ncc(Br)cc1S(=O)(=O)Nc1ccnn1C +COCC1C(=O)NCC12CCN(C(=O)Cc1ccc(OC)cc1)CC2 +Cc1ccc(C2(O)CCN(C(=O)c3ccc4ncccc4c3)CC2)nc1 +Cc1nnc(SCC(=O)Nc2cc(Cl)ccc2Cl)n1C +CC(c1cccc(O)c1)N(C)C(=O)Nc1ccnc(C(=O)N(C)C)c1 +Cc1cc(F)ccc1NC(=O)Cn1nnc2ccccc21 +Nc1ccc(F)c(NC(=O)CCN2CCc3c(Cl)cccc3C2)c1 +C#CCC(OC(=O)c1cc(C(N)=O)cn1C)C1CC1 +CCOc1ccc(CC(=O)N2CCN(CC(O)CC)CC2)cc1 +CCCC(C#N)(CCC)NC(=O)c1ccc2c(c1)CCC(=O)N2C +O=C(Cc1c(F)cccc1Cl)NCc1cccnc1 +CCNC(=O)CNC(=O)Nc1ccc(C(=O)NC2CCCCC2)cc1 +CN(C(=O)CCSc1ccccn1)c1cccnc1N1CCCC1 +CC(C)(C)NC(=O)N1CCC(Oc2cccnn2)CC1 +NC(=O)c1ccccc1NC(=O)c1cc(-c2ccccc2Cl)[nH]n1 +C=C(C)Cn1cnc2c(oc3nc4c(cc32)CCCC4)c1=O +Cc1cnc(C(=O)NC(C)c2ccc(Cl)cc2Cl)cn1 +Nc1c(-c2nc(-c3cccs3)no2)nnn1-c1ccc(F)cc1 +COc1cc(C(C)=O)ccc1OCC(=O)Oc1cccc(F)c1 +CN(Cc1nc2ccccc2s1)C(=O)c1cccc(-c2ccoc2)c1 +CC(C)(C)OC(=O)COC(=O)c1csc(S(N)(=O)=O)c1 +O=C(NCCN1CCN(C(=O)c2ccsc2)CC1)C1CCC1 +CC(=O)Nc1cccc(-c2cccc(OC(C)C(N)=O)c2)c1 +CC1CN(C(=O)c2ccc(N3CCCS3(=O)=O)cc2)CC(C)O1 +O=C(c1ccc[nH]c1=O)N1CCCC1c1ccc[nH]1 +CCOCc1cccc(NC(=O)c2cccnc2N2CCCCC2)c1 +COCCOc1cccc(NCc2cc3ccccc3[nH]c2=O)c1 +CCOC(=O)c1cc2cc(NC(=O)c3ccc[nH]c3=O)ccc2s1 +O=C(Nc1nnc(C2CCCO2)s1)c1ccc2nnnn2c1 +O=C(NCc1csc(N2CCOCC2)n1)c1cnn[nH]1 +CCc1cccc(OCc2c(CO)nnn2CC)c1 +COc1ccc(OC)c(NC(=O)c2cc(OC)c3c(c2)OCCO3)c1 +CCc1cc(C(=O)Nc2ccc(OCc3nccn3C)cc2)[nH]n1 +Cc1nsc(C(=O)N2CCN(C3CCCCC3)CC2)n1 +O=C(CCc1cnccn1)NC1CC(=O)N(CC2CCCCC2)C1 +COc1ccc(F)cc1NC(=O)C1CCCN1C(=O)OC(C)(C)C +Cc1ccc(-c2n[nH]cc2CN2CCOC(c3ccccc3C)C2)o1 +Cc1ccc(C(=O)NC(C(=O)NC(C)CO)C(C)C)cc1 +COc1cccc(-c2nc(CN3CCOCC3C)cs2)c1OC +CC(=O)N1CCC(C(=O)N2CCCC2Cc2cccc(F)c2)CC1 +Cc1cc(C)n2nc(SCCc3ccccc3)nc2n1 +Cc1cc(C)c2c(c1)NC(NCCOCCO)=NS2(=O)=O +CCOC(=O)N1CCN(C(=O)c2ccc3c4c(cccc24)CC3)CC1 +CC(=O)NCCCNC(=O)c1cc(-c2ccncc2)nc2ccccc12 +COCC(=O)NCc1nc(-c2cccc(F)c2)c(-c2ccccn2)[nH]1 +CC(C)c1cc(=O)c2cc3c(cc2[nH]1)OCCCO3 +Nc1ccc2oc(CC(=O)Nc3cccnc3)nc2c1 +CC1(C)C(=O)Nc2cc3nc(-c4ccncc4)[nH]c3cc21 +CC(C(N)=O)N1CCc2c(N)cc(Cl)cc2C1 +Cc1ccccc1C(=O)NCCC(=O)NC1CCCCC1 +CN(CC1CC1)C(=O)CCNS(=O)(=O)c1cccs1 +CC(=O)Nc1cccc(CNC(=O)Nc2nccs2)c1 +CCC(C)NC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1c(Cl)c(C(=O)N2Cc3cnc(CC(C)C)nc3C2)nn1C +CC(C)NC(=O)Nc1ccccc1C(=O)OC(C)C +O=C(NCCc1ccccc1)c1nc2c(o1)CN(Cc1cccnc1)C2 +CC(C)Cc1ccc(S(=O)(=O)N(CC(N)=O)C2CCCC2)cc1 +COc1cc(O)cc2c1CCNC2c1n[nH]c2ccccc12 +CC(O)C(=O)N1CCC2(CCC(=O)N(Cc3ccccc3)C2)CC1 +COCC(C)NC(=O)CSc1ccc(F)cc1 +Nc1c(NCc2cccnc2)ncnc1NC1CCCCC1 +CCOc1ccc(NC(=O)c2ccccc2)c(N)c1 +CCCNC(=O)CN(C)C(=O)CNc1ccc(F)c(Cl)c1 +CCCn1c(C2CC(=O)N(c3cccc(OC)c3)C2)nc2ccccc21 +CC1CC(NC(=O)Cc2ccc(O)cc2Cl)CC(C)O1 +N#Cc1ccc(-c2noc(CCc3nncn3-c3ccccc3)n2)nc1 +Cc1nc(C(=O)N2CCC(Sc3ccccc3C)CC2)cs1 +Cc1cc(C)c2c(c1)OC(C)(C)C(N1CCC(=O)CC1)C2O +O=C1CCc2cc(NC(=O)N3CCCC4CCCC43)ccc2N1 +CC(=O)N1CCC(c2cc(-c3cccc(F)c3)n(C)n2)CC1 +Cn1c(C(=O)NCC(=O)Nc2ccc3c(c2)OCO3)cc2occc21 +Cc1cc(C(=O)Nc2ccc(-c3ncn(C)n3)cc2)cc(=O)[nH]1 +Cc1noc(CNc2cc3ccccc3c(=O)[nH]2)n1 +Nc1ccc2c(c1)CCN2C(=O)Cc1cccc(F)c1 +O=C(c1cn(CC2COc3ccccc3O2)nn1)N1CCCC1 +O=C1NCCCCC1NC(=O)N1CCCc2cc(F)ccc21 +O=C(CCn1cncn1)Nc1nc(-c2cccc3ccccc23)cs1 +N#Cc1ccc(-c2cccs2)nc1SCc1ccccn1 +COc1ccc(C(=O)NCCCOc2ccccc2)nn1 +CSc1ccc(CN2CCN(c3nccs3)CC2)cc1 +CCn1nc(C(C)C)cc1C(=O)NCCc1ncnn1C +COc1ccc(OCC(=O)Nc2c(C)cc(C)nc2C)cc1 +COC(=O)c1cccc(N=C(O)Cn2ccnc2)c1 +CN(CC1CCCC1)C(=O)CCNC(=O)c1ccoc1 +COc1cc(CNc2ccccc2SC)cc2c1OCO2 +Cc1nc(-c2c[nH]c(C(=O)N3CCOC(C)C3)c2)cs1 +CN1CCN(C(=O)c2ccc(Br)cc2)CC1 +Cc1nnc(C2CC3OCCC3N(C(=O)Cc3cccs3)C2)o1 +CCOCCSc1nnc(-c2ccccc2)n1C +CC(NC(=O)c1cccc(F)c1F)c1ccccc1 +COc1ccccc1OCCCc1cccc(C#N)n1 +CN(C)C(=O)CNC(=O)CC12CC3CC(CC(C3)C1)C2 +COc1cc(C(C)=O)ccc1OCC(=O)NCC1CCCCC1 +CCOC(=O)CC1CCN(C(=O)C2COc3ccc(F)cc3C2)CC1 +Cc1ccccc1COC1CN(C(=O)c2cc(C(C)C)on2)C1 +CCCCNC(=O)CSc1cc(=O)n(CC)c2ccccc12 +COc1ccc(CCCNC(=O)NCc2ccc3c(c2)OCO3)cc1 +Cn1cc(Br)c2c1-c1oncc1CC2 +CC(=O)c1cccc(NC(=O)C2CN(C(=O)c3cc(C)on3)C2)c1 +COc1ccc(Cl)cc1N(C)C(=O)c1cc(-c2ccccn2)no1 +CC(C)OC(=O)C(C)N(C)C(=O)C1COc2ccc(F)cc2C1 +Cc1csc(=O)n1CCC(=O)N1CCCc2ccccc21 +COc1cccc2c1OCC(NCc1c[nH]nc1-c1ccccc1)C2 +O=C(Nc1nnc(C2=COCCO2)o1)c1cccc(Cl)c1 +Nc1cnn(CCCCc2ccc3nc(C4CC4)[nH]c3c2)c1 +CC(O)CN(CCO)S(=O)(=O)c1ccccc1 +CC(C)NC(=O)Cn1ncn2c(cc3ccccc32)c1=O +O=C(CNS(=O)(=O)c1ccccc1F)c1cccs1 +O=C(NCc1ccoc1)Nc1ccc(F)cc1Cl +Cc1ccc(F)c(C(=O)N(CCC(N)=O)Cc2ccccc2)c1 +N#CC1(C(=O)Nc2ccc(NCCc3ccccc3)cc2)CCC1 +CN(CC1CCCCC1)C(=O)CSc1ncn(-c2ccccc2)n1 +CNC(=O)CN(C)C(=O)c1csc(COc2ccc(C)cc2)n1 +NS(=O)(=O)c1cc(C(F)(F)F)ccc1NCc1ccccc1 +Cn1cnc2cc(OC(=O)c3cc(-c4ccc(F)cc4)n[nH]3)ccc21 +COC(=O)c1cc(Br)c(=O)n(-c2nccs2)c1 +COc1ccccc1-c1c(C#N)nnn1CCCO +Cc1cn2c(CN(C)Cc3nccc(N)n3)c(C)nc2s1 +CC(C)CC(=O)Nc1ccc2[nH]c(CCCO)nc2c1 +N#CC1(NC(=O)COC(=O)c2cc(=O)[nH]c3ccccc23)CCCC1 +COCCNC(=O)Cn1ccc2cc(Br)ccc21 +CC(C)c1ccc(-c2ccnc3c(C(=O)NC4CC4)cnn23)cc1 +CN1C(=O)C(C)(C)c2cc(-c3coc(N)n3)ccc21 +O=C(NCC(c1cccnc1)N1CCc2ccccc21)c1ccco1 +COCCOc1ncccc1C(=O)Nc1cc(OC)ccc1Cl +Cc1ccc(Sc2ncnc(-n3ccnc3)c2N)cc1 +CCOc1ccccc1N1CC(C(=O)NC(C)C)CC1=O +CCC(CO)N(Cc1ccccn1)C(=O)c1cccnc1NC +CCC(C)NC(=O)CSc1nnc(C2CC2)n1C1CC1 +CCNc1ccc(Cl)c(C(=O)NCc2nccs2)n1 +COC(=O)C1CC(=O)N(C(C)C23CC4CC(CC(C4)C2)C3)C1 +O=C(NCc1n[nH]c(=O)c2ccccc12)c1ccc(C(F)(F)F)cc1 +CC(=O)Nc1ccc(C(=O)NCCc2ccccc2)cc1 +CCc1ccc2c(CN3CCOCC3C3CC3)cc(=O)oc2c1 +CCc1nc(NC(=O)c2ccc(Cn3cncn3)cc2)sc1C +Cc1cc(NC(=O)c2ccccn2)ncc1Br +C#CCOc1nc(OCC#C)nc(N2CCCCC2)n1 +c1cncc(CN2CC(Oc3cccnc3)C3OCCCC32)c1 +OCCOc1ccccc1OCc1cc(F)ccc1Br +O=S(=O)(Cc1ccccc1)NCC(O)Cc1ccccc1 +Cc1cc(C(=O)N2CCN(C(=O)c3ccc(Cl)cc3O)CC2)on1 +O=C(Cc1ccc(F)cc1)NCc1cnn2ccccc12 +N#Cc1cccc(NC(=O)c2ccc3c(c2)OCCCO3)c1 +CC(=O)c1ccc(C#N)c(SCC(=O)Nc2ccccc2)n1 +Cc1ccc2nc(C)c(C(=O)NCC(=O)NC3CC3)cc2c1 +Cc1ncnc(-c2ccc3c(c2)N(C)C(=O)CCO3)c1N +Cc1cccc(CCC(=O)NCCNC(=O)c2ccc(O)cc2)c1 +COCC(C)OC(=O)Cc1ccc(NC(C)=O)cc1 +CC1CN(C(=O)CCNc2cnc3ccccc3n2)CC(C)O1 +CCc1nnc(NCCc2ccc3c(c2)OCO3)o1 +COC(=O)c1ccc(C(=O)NC2CCCCC2)s1 +CC(C)(O)C#Cc1ccc(C(=O)NCc2nccs2)o1 +CC(C)C(=O)Nc1cccc(NCC(=O)NCC(F)(F)F)c1 +O=C(NCCc1ccc(Cl)cc1)c1cccnc1-n1cncn1 +Cc1ccc(-c2n[nH]cc2CN2CCOC(C#N)C2)cc1 +Cc1oc2ncn(CCC(=O)NCc3cccs3)c(=O)c2c1C +Cc1csc(NC(=O)c2cc3c(s2)CCCC3)n1 +CCCN(Cc1cc(Br)c(O)c(OC)c1)CC(F)F +Cc1ccc(NCC(=O)Nc2cccc(C#N)c2)c(F)c1 +COc1ccc(C(NC(=O)CCc2ccccc2)c2nccn2C)cc1 +CCOc1cccc(OCCCN2C(=O)CCS2(=O)=O)c1 +Cc1nc(CN2CCN(C(=O)c3cnc4ccccc4n3)CC2)no1 +CCOc1ccccc1CC(C#N)C(=O)N1CCN(C)CC1 +COC(=O)c1cc(Br)cc2c1c(C)nn2C(C)C +Cc1ccc(CNc2cccc(-c3nccs3)c2)o1 +CC(C)COc1cccc(C(=O)NC(C)C(N)=O)c1 +O=C1Cc2cc(NC(=O)Nc3cc(Cl)ccc3F)ccc2N1 +Cc1ccc(C(=O)N2CCOCC3(CCC(Cn4cncn4)O3)C2)o1 +CN(CCC#N)S(=O)(=O)N1CCCC1c1ccccc1Cl +Cc1cc(C(=O)N2CCC(Cc3cccc(C(N)=O)c3)C2)[nH]n1 +COCc1ncc(C(=O)Nc2ncccn2)c(N)n1 +CSc1ccc(C)c(C(=O)Nc2ccncc2)c1 +COCCc1nnc2n1NC(c1ccc(OC)cc1)CS2 +COc1ccc(NC(=O)NCCNC(=O)OC(C)(C)C)cc1 +CCN(Cc1ccncc1)C(=O)Nc1ccc(F)cc1 +CC(C(=O)NC1CC1)S(=O)(=O)c1ccc(C(F)(F)F)cn1 +Cc1ccc(OCC(=O)N2CCN(S(=O)(=O)N(C)C)CC2)cc1 +CSc1ncccc1C(=O)N1CCN(C(=O)C2CCCO2)CC1 +COc1ccccc1C(NCc1cnc(C)s1)c1ccccn1 +COCCN(CC(=O)N(C)C)C(=O)Cc1ccc[nH]1 +O=S(=O)(c1ccccc1)N1CCC(O)C1Cc1cccnc1 +O=c1[nH]nc(CN2CCN(c3ccccc3O)CC2)[nH]1 +Cc1cc(C)c(NC(=O)c2ccc(OCC(F)(F)F)nc2)c(C)n1 +CC(C)CCn1c(C(C)NC(=O)c2ccccn2)nc2ccccc21 +Cc1ccccc1NC(=O)C(C)Sc1nnnn1-c1ccccc1 +Cc1ccc(NC(=O)NCCCOCC2CCOC2)cc1C +CCCNC(=O)CNS(=O)(=O)c1c(C)c(C)cc(C)c1C +CNc1c(N)n(Cc2ccccc2Cl)c(=O)[nH]c1=O +Cc1ccccc1NC(=O)COc1cccc(N)c1 +CC(=O)Nc1ccc(NC(=O)NCCCN(C)c2ccccc2)cc1 +C=CCN(Cc1cccc(C#N)c1)C(=O)c1ccc(C(N)=O)cc1 +O=C(CO)N1CCN(C(=O)c2cccc(C(F)(F)F)c2)CC1 +O=S(=O)(c1ccccc1)N1CCCC1c1ccccc1F +O=C(c1cn2ccsc2n1)N1CCOC(c2ccc(Cl)cc2)C1 +CC1CN(C(=O)CCn2nc(-c3cccs3)oc2=O)C(C)CO1 +O=C(Nc1ccccc1OC(F)(F)F)c1ccc(-n2cncn2)nc1 +O=C(Nc1ccc2c(c1)OCO2)N1CCN(C(=O)C2CCCO2)CC1 +CC(C)(C)c1noc(CCC(=O)N2CCN(C(=O)CO)CC2)n1 +CC(C)(C)OC(=O)NCC1CCN(C(=O)c2ccsc2)C1 +CCC1CN(C(=O)c2ccc(F)cc2)CCC1CC(=O)NC1CC1 +O=C(CC1CCCCC1)N1CC(c2nc(-c3cnccn3)no2)C1 +CCOC(=O)C=C(C)NS(=O)(=O)c1ccc(NC(C)=O)cc1 +CC(C)(C)NC(=O)CSc1nnnn1C1CC1 +CC(c1ccco1)N(C(=O)Nc1cccn(C)c1=O)C1CC1 +CC(C)(C)NC(=O)COC(=O)c1ccc(F)c(Cl)c1 +O=C(c1ccc2c(c1)OCO2)N(Cc1ccccc1)c1ccccn1 +Cc1cc(C)cc(NC(=O)c2cc3cccnc3nc2N)c1 +O=C(CCn1cncn1)N1CCCC(CCc2ccc(F)cc2F)C1 +Cc1ccc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)c(F)c1 +C=C(C)CN(C)C(=O)c1cc(COc2ccc(F)cc2F)on1 +C#CCNC(=O)NCc1cccc(OCc2ccccc2)c1 +CCc1ccccc1NC(=O)c1cc(C)c(C)c(S(N)(=O)=O)c1 +CCC(C)NS(=O)(=O)c1ccc(Br)cc1 +CCc1noc(CN(C)Cc2cn(C)nc2-c2ccncc2)n1 +COc1ccccc1C(=O)Nc1cccc(S(C)=O)c1 +CC(C)c1cccc(CN(C)CCc2ccncc2)n1 +CC(=O)NCc1ccc(C(=O)Nc2ccc(Cl)cc2Cl)s1 +CC1CCN(c2cnn(-c3ccccc3)c(=O)c2Br)CC1 +Cc1occc1C(=O)Nc1nc(CC(=O)OC2CCCC2)cs1 +C1=CCC(c2cn(Cc3cnc4ccccc4c3)nn2)CC1 +Cn1cc(CNC(=O)c2ccc(Cl)c(N)c2)cn1 +Cc1noc2nc(-c3ccccc3)cc(C(=O)N(C)C(C)C)c12 +CC(=O)NC1CCCN(S(=O)(=O)c2cnn(-c3ccccc3)c2)C1 +CC1CN(S(=O)(=O)NC2CCCn3ncnc32)CC(C)O1 +CC(C)c1nnc(NC(=O)CSc2nncn2C(C)C)s1 +O=C(c1ccc(N2CCCCC2)cc1)N1CCC(O)C1 +CCOc1ccccc1S(=O)(=O)NCC(C)(O)c1cccs1 +CCN(C(=O)c1ccccc1N)c1ccc(F)cc1 +N#Cc1ncnc(C(F)(F)F)c1Cc1ccc(F)cc1 +CC(C)=CC1C(C(=O)Nc2ccc[nH]c2=O)C1(C)C +Cc1ccc(NS(=O)(=O)c2ccccc2N)cc1C +O=C(COc1ccc(F)cc1)N1CCN(Cc2ccc(F)cc2)CC1 +CN1CC(C(=O)N2CCC(Oc3ncccc3C#N)CC2)CC1=O +CC(=O)NCC(=O)NCC(=O)Nc1cc(Br)ccc1C +C#Cc1cccc(NC(=O)NCc2sccc2C)c1 +Cc1noc(CNc2ccc3c(c2)Cc2ccccc2-3)n1 +CCCCS(=O)(=O)NCC1(c2ccccc2)CC1 +CC(=O)Nc1sc(C)c(C)c1C(=O)OCC(=O)c1ccccc1 +O=S(=O)(NC1CCSc2ccc(F)cc21)c1cccs1 +CC(=O)Nc1cccc(CNC(=O)NCCSc2ccccc2)c1 +CNC(=O)CNC(=O)C1CCC(=O)N(Cc2ccccc2OC)C1 +COc1cc(Cl)c(-c2nc(C)cc(N)n2)cc1Cl +CCCN(CCC)C(=O)c1csc(Nc2cccnc2)n1 +Cc1nc(NCc2ccncc2)cc(-c2cccc(C(F)(F)F)c2)n1 +CCOC(=O)Cc1csc(NC(=O)c2ccc(C)cc2C)n1 +CNS(=O)(=O)c1cccc(C(C)NC(=O)NC(C)C)c1 +CCOn1c(=O)c(=O)n(OCC)c2ccccc21 +O=C(Nc1nc(-c2cccnc2)cs1)c1n[nH]c2c1CCC2 +Cc1cc(Cl)c(C(=O)Nc2cccc(C)c2C)cn1 +CC1CCCC(CC(=O)N(CCC(N)=O)c2ccccc2)C1 +Cn1c(=O)c2c(-c3ccccc3Cl)n(CCCO)cc2n(C)c1=O +O=C(Cn1ncc2ccccc2c1=O)NCCc1ccncc1 +O=C(c1csc(-c2cccs2)n1)N1CC(O)C1 +O=C(NCc1nnc2ccccn12)c1cc(-c2ccccn2)n[nH]1 +CCC(C)NC(=O)Cn1nnn(-c2ccccc2Cl)c1=O +Cc1cc(NC(=O)NC(c2nccs2)C2CC2)c2ncccc2c1 +Cc1cc(CNC(=O)C2(C)CC(=O)N=C3C=CC=CN32)ccc1F +CC1=C(C(N)=O)C(c2ccccc2)n2nc(-c3cccs3)nc2N1 +C=Cc1ccc(NC(=O)N2CC3CCC(C2)C3O)cc1 +COCCN1CC(C(=O)N2CCCC(C)C2)CC1=O +COC(=O)N(C)c1ccc(NC(=O)NCc2ccnn2C)cc1 +O=C1CCOCCN1Cc1cccc(OC(F)(F)F)c1 +CC(C(=O)NCC(F)(F)F)N(C)Cc1nccs1 +Cc1nc2ccccc2n(Cc2noc(C3CCCC3)n2)c1=O +CCCCOc1nc(C)nc(NCc2ccccc2)c1N +COc1ccc(Cl)cc1CCNC(=O)CCn1cncn1 +CC(Sc1nncs1)C(=O)Nc1ccc(Cl)cn1 +O=C(NCCO)c1cnc2scc(-c3ccccc3)n2c1=O +CC(Sc1n[nH]c(N)n1)c1nc(C2CC2)no1 +Cc1csc(-c2cccc(NC(=O)NCc3ncn(C)n3)c2)n1 +CC(=O)NC(C(=O)NC1CCCCC1C)C(C)C +CC(C)NC(=O)c1cccc(N2CCCCS2(=O)=O)c1 +CCN(CC(=O)Nc1c(F)cccc1F)C(=O)Cc1ccccc1 +CC(=O)c1ccc(S(=O)(=O)Cc2cccc(C#N)c2)cc1 +FC(F)Oc1ccccc1CNc1ccc2nnnn2n1 +Nc1cc(F)cc2c(C(=O)NCc3ccncc3)nccc12 +COCC1CN(C(=O)NCc2ccc3ccccc3c2)CCO1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)Nc1ccccc1C)O2 +Fc1ccc2[nH]c(C(Cl)(Cl)Cl)nc2c1 +O=C1C(N2CCN(CCO)CC2)CCN1c1ccccc1F +COC(=O)CCC(=O)Nc1ccc(-c2nc3cc(C)ccc3[nH]2)cc1 +CC(=O)NCCNC(=O)N(CC1CCCCC1)C1CC1 +Cc1ocnc1C(=O)NC(Cc1ncc[nH]1)c1ccccc1 +CN(CCc1ccccn1)C(=O)NCCN1CCOCC1 +Cc1cc(C(C#N)C(=O)c2ccc(Cl)cc2)nc(C)n1 +Cc1nc(C)c(C2NCCc3ccc4c(c32)CCO4)s1 +CN(Cc1nc2ccccc2s1)C(=O)c1cnccn1 +CC(C)Oc1ncccc1CNS(=O)(=O)C(C)C +COc1cccc(CCC23C=CC(O2)C(CO)C3CO)c1 +CC1CCN(C(=O)C(C)Sc2ncnc3ccccc23)CC1 +CS(=O)(=O)N1Cc2cncn2CC(COc2ncccc2F)C1 +CC(C)Cn1c(Cn2ccnc2)nc2cc(NS(C)(=O)=O)ccc21 +COc1ccccc1C1CC(=O)CC(Nc2nonc2N)C1 +CCOCC1CCCN(C(=O)c2ccc(C)cc2)C1 +CCOc1ccccc1NC(=O)Cn1cnc(-c2ccccc2)cc1=O +Cc1noc(-c2cccnc2N2CCC(NC(=O)c3ccoc3)C2)n1 +C#CCNC(=O)NCC1(Sc2ccccc2)CC1 +CCc1cnc(C)nc1N(C)CCc1ccccn1 +CC(C)NC(=O)CN1CCN(CC(=O)NC2CCCCC2)CC1 +O=C(c1ccc(Br)cc1)N1CCCC1 +Cc1noc(CNC(=O)COc2ccc(Cl)cc2Cl)n1 +O=C(NCc1cccc(F)c1)c1n[nH]c2c1CCc1ncccc1-2 +CC(O)C(=O)N1CCN(Cc2cc3cc(F)ccc3o2)CC1 +Cc1cc(Cl)ccc1OCc1ncc(C(N)=O)c(N)n1 +Cc1cc(NC(=O)CSc2nnc(C(C)C)o2)no1 +Cc1ccc(N2CCC3OCCC(C(=O)NC4CC4)C3C2)nn1 +COC(=O)c1ccc(S(=O)(=O)NCC(C)(C)c2ccncc2)cc1 +CC(=O)c1cc(Cl)c2c(c1)NC(=O)CC(C)O2 +CCc1c(C)nn(C(=O)COc2ccccc2)c1C +CCN(CC)C(=O)C1CCN(C(=O)c2ccsc2)CC1 +CCOc1nnc(CSc2nc(C)cs2)s1 +CN(C)C(=O)CCOC(=O)Cc1ccc(F)c(F)c1 +Cc1cc(CN2CCN(S(=O)(=O)N(C)C(C)C)CC2)no1 +Cc1noc2nc(-c3cccs3)cc(C(=O)N3CCOC(C)C3)c12 +CC(=O)c1ccc(NC(=O)c2cc(F)c(F)c(F)c2)cc1C +Cc1cnn(CCC(=O)Nc2ccc(NC(=O)NC(C)C)cc2)c1 +O=C(NCCc1nc[nH]n1)Nc1ccn(-c2ncccc2Cl)n1 +COC(=O)CCn1c(SC(C)C(N)=O)nc2ccccc2c1=O +COC(=O)c1cnc2nc(C)ccc2c1Nc1ccc(F)c(C#N)c1 +COc1cc(C)c(NS(C)(=O)=O)cc1C(C)C +CCN(CC)C(=O)N1CCN(Cc2ccc(OC)nc2)CC1 +CC(C)(C)OC(=O)NCC1NCCc2c1ccc(F)c2O +CCOc1cc(OCC)cc(C(=O)Nc2cccc(C(C)=O)c2)c1 +COc1ccc(-c2cc(C(C)=O)c(C)n2C2CC2)cc1 +O=S(=O)(c1ccccc1)N1CCCC1c1nnc2ccccn12 +Cc1cc(C)cc(NC(=O)COC(=O)c2cnccn2)c1 +O=C(Nc1cccnc1)C1CN(c2ncc(F)cn2)CC2OCCC21 +CC(Sc1nnnn1C)C(=O)Nc1ccc(F)cc1Cl +O=C(Cn1cnc2c([nH]c3ccccc32)c1=O)NCc1ccccn1 +CC(=O)c1[nH]c(C)c(C(=O)NC(c2nccn2C)C(C)C)c1C +COC(=O)CNCc1cc(-c2ccccc2)cs1 +CC(C)C(=O)Nc1ccc(OCC(=O)NCC(F)(F)F)cc1 +Cc1nnc(-c2sc(C)nc2-c2ccccc2)o1 +CCOC(=O)CCC(C)NC(=O)N1CCCCC1C(C)C +CNC(=O)CNC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +Nc1cc2c(cc1NC(=O)Cc1cccs1)CCCC2 +COc1ccc(C2CCCN2C(=O)c2ccc[nH]c2=O)cc1OC +CC(C)NC(=O)c1cc(NC(=O)Cc2ccccc2)n(C)n1 +Fc1ccc(OCCCOc2ccc(-n3cnnn3)cc2)cc1 +CN(CCO)C(=O)OCC1c2ccccc2-c2ccccc21 +O=C(NCCn1ncc2ccccc2c1=O)c1cccnc1 +Cc1cccc(C(=O)OC(C)C(=O)Nc2sccc2C#N)c1N +Cc1ccc(S(=O)(=O)N2CCOCC2CC(C)C)c(F)c1 +CC(=O)c1ccc(OS(=O)(=O)c2c(C)noc2C)cc1 +CC(NC(=O)c1ccc(F)cc1Cl)c1nnc2ccccn12 +CN(C(=O)CSc1nnc(-c2ccncc2)n1C)C1CC1 +O=c1[nH]c2ccccc2c(=O)n1CCc1cccnc1 +CC1CCC(N(C(=O)C(C)NC(N)=O)C2CC2)CC1 +COc1cc[nH]c(=NS(=O)(=O)c2sccc2OC)c1 +CCn1nc(C)c(Cl)c1C(=O)NC1CCCC1 +CC1CCN(C(=O)c2ccc(-n3cccn3)nc2)CC1 +CCn1nc(C)cc1C(=O)NC1C(c2cccnc2)CC(O)C1O +COc1ccc(-c2nnc(-c3ccccc3N)o2)cc1 +COc1cc(NS(=O)(=O)c2cn[nH]c2C)c(OC)cc1Cl +CC(C)(C)NC(=O)CNC(=O)c1cc(Cl)cc(Cl)c1 +Nc1ccc(-c2nc(Cc3ccc(F)cc3)n[nH]2)cc1 +Cc1nnc(SC(C)C(=O)NCc2ccc(Cl)cc2)o1 +CC(Nc1ncnc(Oc2ccccc2)c1N)c1ccccc1 +CCSc1nc2n(n1)C(c1ccccc1OC)C(C(N)=O)=C(C)N2 +COCc1c(C(=O)N2CCc3sccc3C2)oc2ccccc12 +Cn1cccc1C(=O)N1CC2OCC(=O)N(Cc3ccncc3)C2C1 +CCC(=O)Nc1ccc2nc(SCC(=O)N3CCCC3)sc2c1 +CCN(CC)C(=O)c1ccc(OCc2cn3ccccc3n2)cc1 +CC(c1ccccc1)N1CCN(C(=O)c2cccc(F)c2)CC1 +Cc1cccc(C)c1NC(=O)COC(=O)CC(C)c1ccccc1 +CCn1nccc1C1CCCN1C(=O)Nc1ccccc1Cl +Cc1nc(C)c(C(=O)NCCNc2cccc(F)c2C#N)s1 +O=C(Nc1cc(F)ccc1F)NC(C1CC1)C1CC1 +CCC(C)NC(=O)C(C)NC(=O)Nc1ccc(C)c(C(F)(F)F)c1 +Nc1c(-c2ccc(F)c(F)c2)nnn1-c1ccccc1O +CC(C)CNC(=O)NCc1cnn(Cc2ccccc2)c1 +O=C(COc1ccc(Br)cc1F)NCCO +COC(=O)CSc1ccsc1C(=O)Nc1ccc(F)cc1F +CC(=O)c1ccc(C(=O)Nc2ccc3c(c2)C(=O)CCC3)cc1 +COc1ccc(Cc2nnc(NC(=O)c3ccc(F)nc3)s2)cc1 +COc1ccc(NC(=O)CN2CCc3ccccc32)cc1OC +Nc1cc2c(c(Cn3cc(Br)cn3)c1)OCOC2 +COc1ccc2cc(C(=O)Nc3ccc(Cl)cn3)c(=O)oc2c1 +COc1cccc(C(=O)Nc2cccc(C)n2)c1OC(F)F +CCn1nnc2cc(C(=O)NC3CCCc4ccccc43)ccc21 +CCOC(=O)CCc1nnc(-c2cccc(N)c2)o1 +Cc1noc(C)c1C(C)NC(=O)COCc1ccccc1Cl +COCC(=O)NC(C(=O)N1CC(c2ccccc2)CC1C)C(C)C +Cc1noc(C)c1CC(=O)N1CCN(c2ccccc2F)CC1 +Cc1ccc(C(=O)N2CCC(Oc3ccccc3)CC2)cc1 +CC(C)(Oc1ccc(F)cc1)C(=O)Nc1cccc(C(N)=O)c1 +c1coc(-c2nc(N3CCOCC3)ncc2-c2ccncc2)c1 +O=C(c1ccc(F)cc1)N1CCOC(c2ccc(F)cc2)C1 +O=C(NCc1nncn1C1CC1)Nc1ccc(OC2CCOC2)cc1 +Cc1cc(CC(C)NC(=O)c2ccc(C)c(N3CCNC3=O)c2)[nH]n1 +O=C(C1CCCN1C(=O)C1CC1)N1CCN(c2ccc(F)cc2)CC1 +CC(NC(=O)c1ccc(Cl)c(N)c1)C1CCCO1 +c1cc2ccc(NCCc3noc(C4CCCO4)n3)nc2[nH]1 +COC(=O)Cc1ccc(OC(=O)c2ccc(-n3cncn3)cc2)cc1 +COC(=O)CCC(=O)NCc1c(F)cccc1Cl +CS(=O)(=O)NC1CCN(c2snc3ccccc23)CC1 +OCc1ccc(-c2c(-c3ccccc3)ncn2CCc2cn[nH]c2)o1 +CCOc1cc2c(cc1CNC(=O)Nc1nncs1)OC(C)C2 +Cc1cc(C)cc(OC(=O)CCCNC(=O)c2ccsc2)c1 +O=C(c1cc(Cl)ccc1F)N1CCc2[nH]cnc2C12CCCC2 +CCN(Cc1cccc(Cl)c1)C(=O)CNC(=O)OC +O=C1CCC2(CCCN(C(=O)c3ccc(O)cc3)C2)CN1CCO +CCCNc1c(N)cc(C#N)cc1Br +CC(NC(=O)c1ccco1)c1nc(-c2ccc3c(c2)ncn3C)no1 +CN(c1ncccc1C#N)C1CCN(C(=O)OC(C)(C)C)C1 +CCN(CC)S(=O)(=O)NCCc1c[nH]c2ccccc12 +O=C(CCC1NCCc2ccc(F)cc21)c1ccccc1 +Cc1cccc(N(C)C(=O)c2cnc(Cc3ccccc3)s2)n1 +CCCn1cc(CN2CCOCC2)c2ccccc21 +COC(=O)c1sccc1NC(=O)COc1ccccc1 +C=CCN1C(=O)NC(c2csc(CC)n2)C(C(=O)OC)=C1C +COc1ccc(OC)c(CC(=O)Nc2ccc(F)cc2C)c1 +COC(=O)c1c(C)ccc(F)c1NC(=O)COc1ccccc1OC +CC(=O)Nc1ccc(F)c(C(=O)Nc2ccc(-c3cnco3)cc2)c1 +C#Cc1cccc(NS(=O)(=O)c2ccc(C)c(F)c2)c1 +COC(=O)c1cc(CNC(=O)c2n[nH]c3ccccc23)ccc1OC +CNC(=O)CCc1ccc(S(=O)(=O)N(C)C)cc1 +NC1=Nn2c(nnc2-c2cc(F)ccc2F)SC1 +O=C(NCCOc1ccc2c(c1)CCC2)C1CCOC1 +CC(=O)c1cccc(NC(=O)CSc2nc3ccccc3[nH]2)c1 +CC1CCCCN1S(=O)(=O)c1cccc(C(=O)NC(C)(C)C)c1 +CCC(C)NC(=O)CN(C1CCCCC1)S(C)(=O)=O +CC(=O)Nc1cc(NC(=O)COCc2nc(C)no2)ccc1C +Cc1cc(N2CCCC2=O)ccc1S(=O)(=O)NCC1CC=CCC1 +Cc1cccc(C(=O)NCC2CN(Cc3ccccc3)CCO2)c1C +CCN(CC1CC1)C(=O)NC1CCN(C(=O)c2ccco2)CC1 +CCc1ccccc1NC(=O)CN(C)C(=O)c1ccc2c(c1)OCO2 +O=C(CCOc1ccc(F)cc1)Nc1nccs1 +CCc1ncnc2c1CCN(C(=O)C1CCOC1)CC2 +O=C(Nc1ccccc1SC(F)F)c1cccnc1 +Oc1ccccc1SCc1noc(-c2ccsc2)n1 +COC(=O)C1CCN(C(=O)c2cccnc2)c2ccccc21 +Cc1cc(NC(=O)NC(C)(C)c2cccc(F)c2)n(C)n1 +CCOC(=O)c1ccccc1CN(C)C(F)(F)F +CC(NC(=O)C(C)c1cccs1)c1ccc(N2CCCC2=O)cc1 +COc1ccc(C(=O)NCC(O)c2cccn2C)cc1 +COC(=O)C(C)(COc1ccccc1)NC(C)=O +CCNc1nnc(-c2cc(C(C)C)nn(CC)c2=O)s1 +Fc1ccc2nc(C3CCCN3Cc3cccnc3)[nH]c2c1 +O=C(NCCCO)c1ccccc1CSc1nc2ccccc2[nH]1 +CCN1CCN(C(=O)C(C)Sc2nnc(C)n2N)CC1 +N#Cc1ccccc1OCC(=O)NCC1CCCCC1 +Cc1cc(C)cc(NC(=O)CC2Cn3ncnc3NC2=O)c1 +CC(=O)c1cccc(NC(=O)c2n[nH]c3ccccc23)c1 +N#Cc1cccc(-n2sc3ccccc3c2=O)c1 +COCCOC1CN(C(=O)COc2ccc(Cl)c(C)c2)C1 +CC(C)(C)c1nnc2sc(-c3ccccc3N)nn12 +Cn1c(=O)ccn(CC(=O)Oc2ccccc2F)c1=O +CCC1CCCCN1c1ncnc(NCCC(C)C)c1N +C=CCNC(=O)CN1CCCc2c(C)ccc(F)c21 +C=CCSc1nc(C)cc(Oc2ccc(=O)n(C)n2)n1 +CC(=O)c1ccc(S(=O)(=O)N(C)C2(C#N)CCOC2)cc1 +COCCn1ccc2c(C(=O)NCC3CCCO3)cccc21 +CC1CCN(c2ncc(Br)cn2)CC1 +O=C(Nc1ccncc1)C1CCCN(c2ncccn2)C1 +O=C(Nc1ccc(OCC(F)(F)C(F)F)nc1)C1CC2CCC1O2 +C#CCN1CCN(C(=O)NCc2ccc(Cl)cc2OC)CC1 +CCCOc1ccc(C(=O)Nc2cccc(C(=O)N(C)C)c2)cc1 +Cc1nn(C)cc1S(=O)(=O)N1CC(C)CC(C)C1 +O=C(Cc1ccccc1)Nc1ccc(S(=O)(=O)C(F)F)cc1 +COc1ccccc1-c1nc2cc(Cl)cnc2n1CCC#N +CC(=O)N1c2ccccc2C(=O)C1N(CC(C)C)CC(C)C +NC(=O)C(c1ccccc1)N1CCOC(c2ccc(Cl)cc2)C1 +CCc1cnc(C)nc1N1Cc2cnn(CCO)c2C1 +Cc1noc(C)c1C(C)NC(=O)c1cn(CC(=O)N(C)C)nn1 +O=C1CCc2cc(S(=O)(=O)NCCc3cccc(F)c3)ccc2N1 +CC(C)c1nncn1CCNC(=O)Cc1c[nH]c2ccc(Cl)cc12 +Cn1cc(CCOC(=O)CCn2nnc3ccccc3c2=O)cn1 +CCCCn1c(N)c(N(CC)Cc2n[nH]c(=O)[nH]2)c(=O)[nH]c1=O +O=C(Nc1ccc(S(=O)(=O)C(F)F)cc1)NC1CCCCCC1 +CCn1c(C(=O)NC2CCCCC2)nc2ccccc21 +COc1cccc(CCNc2ncnc3[nH]cnc23)c1 +CCN(CC)C(=O)c1cn(CC(C)C)c2cccc(N)c2c1=O +CCC(C)n1ncc(C(=O)Nc2cc(F)c(F)c(F)c2)c1C1CC1 +CCCn1nc(C(=O)NCCOc2ccc(C)cc2)ccc1=O +CC(C)c1nccn1Cc1ccc(S(=O)(=O)N(C)C)cc1 +Fc1ccc(Cn2nc(-c3cccnc3)c3c2CCNC3)c(F)c1 +COc1cccc(C2CC(C)(O)Oc3cc4c(cc32)OCO4)c1 +C=CCSc1nnc(-c2ccc(Br)cc2)n1N +CCCCn1c(C)ccc(-c2nnc(NCC)s2)c1=O +COc1cccc(N2CCN(C(=O)c3cccc4c3ccn4C)CC2)c1 +O=C(NCc1ccccc1)c1nc(-c2cnccn2)no1 +COC(=O)c1cc(-c2ccc(SC)cc2)nn1C +CC(C)CN1C(=O)c2ccccc2NC1c1csc(C2CC2)n1 +Cc1ccc(NC(=O)Cn2c(=O)c(C#N)c3n(c2=O)CCC3)cc1C +CCCNC(=O)C(C)NC(=O)Cc1coc2cc(C)ccc12 +O=C(CSc1ccc(-c2ccc(F)cc2)nn1)NCc1ccco1 +CCCOCc1ccccc1CNC(=O)NC1CCCC1 +CCOC(=O)CNC(=O)COc1ccccc1C#N +COC(=O)CC1=Nn2c(nnc2-c2ccccc2)SC1 +CN(Cc1ccccn1)C(=O)NCc1ccc(F)cc1C(F)(F)F +CSc1nnc(SCC(=O)N(C)c2ccccc2)s1 +OCCNc1c(F)c(F)nc(N2CCCCC2)c1F +CC(C)CNC(=O)c1cc2cn(C3CC3)cc2s1 +Cc1ccc(C(C)NC(=O)CSc2nncs2)cc1C +CCc1ccc(CN2CCN(c3ccc(C#N)cc3)C(=O)C2)nc1 +CN(Cc1cnc(N)nc1)Cc1cc(=O)c2cc(C(N)=O)ccc2[nH]1 +Cc1nc(SCC(=O)Nc2sccc2C#N)nc(C)c1C +CC1CCCN(S(=O)(=O)NC2CCN(c3ncccn3)CC2)C1 +Nc1ccccc1Cn1ccnc1-c1ccc(F)c(F)c1 +CCOC(=O)c1cnc(SCc2cccc(OC)c2)nc1N +CC(Sc1n[nH]c(=O)n1C1CC1)c1nc(-c2ccco2)no1 +CC(C)Oc1nc(N2CCC(CO)CC2)ccc1N +CCOC(=O)C1=C(C)C(C(=O)N(C)Cc2cccs2)=NC1C +NC(=O)c1cccnc1N1CCC(c2ccc3ccccc3c2)C(O)C1 +COc1cccc(CNC(=O)c2csc(-c3cnccn3)n2)c1 +CCCNC(=O)CCCC(=O)N1CCc2cc(F)ccc2C1 +CC(=O)Nc1nc(C(=O)N2c3ccccc3CC2C)cs1 +Cc1nc2ccccc2nc1NCc1ccc(N2CCCC2=O)cc1 +Cc1cc(C(=O)NC2CCCN(C(=O)c3ccccc3)C2)c(C)s1 +CCCS(=O)(=O)c1cc2c(cc1N)OCCO2 +Cc1ccc(OCC(=O)NCc2ccoc2)c(C)c1 +CC(=O)N1CCc2cc(NC(=O)CCOC(C)C)ccc21 +COC(=O)c1ccsc1NC(=O)Cn1c(C)c(C)sc1=O +NS(=O)(=O)c1ccc(NCc2ccco2)c2ncccc12 +O=C(c1ccc2nncn2c1)N1CCC(Oc2cccc(Cl)c2)C1 +CC(C)OCCOC(=O)c1ccc(Br)cc1 +CC1CCC(NC(=O)c2ccc3c(=O)[nH][nH]c(=O)c3c2)CC1 +CC(=O)Nc1cc(NC(=O)NC2CCCCCC2)ccc1F +Nc1nc(-c2ccco2)ncc1C(=O)N1CCOCC1 +O=C(CCn1cnc2ccccc2c1=O)NC1CCCCC1 +CCc1cc2c(=O)n(CC(=O)Nc3ccc(OC)cc3)cnc2s1 +C=CCNS(=O)(=O)c1ccc(C(=O)Nc2ccnc(C)c2)cc1 +c1ccc(C2C(c3ccccc3)N3CCN2CC3)cc1 +CC(=O)c1cccc(NC(=O)CSc2nnc(C(C)(C)C)o2)c1 +Cc1nc2cc(C(=O)NC3CCC(C)CC3)ccc2n1C +Cc1cc(F)ccc1NC(=O)c1cccc2cccnc12 +CN(Cc1cc(Cl)cc(Cl)c1)C(=O)Cn1cc(Cl)cn1 +CC(=O)Nc1ccc(C(=O)NCC#Cc2cccc(Cl)c2)cc1 +Cc1ccc(C(C)NC(=O)Nc2nccs2)s1 +Cc1ccccc1CNC(=O)CSc1nnc(-c2cccs2)o1 +CC(C)(C)OC(=O)N1CCCC1C(=O)NC1CCc2c(F)cccc21 +CC(C)NC(=O)CN1CCN(C(=O)c2ccc(Cl)cc2)CC1 +O=C(CCc1nc(-c2ccncc2)no1)N=c1[nH]nc2ccccn12 +Cc1ccc(NC(=O)CNc2c(C)cccc2C)cc1S(N)(=O)=O +N#Cc1ccc(Sc2ncnc3[nH]ncc23)c(F)c1 +CC(=O)Oc1ccc(NC(=O)c2ccc(F)cc2)cc1 +COc1c(O)c(Cl)cc2c1C(c1cncn1C)NCC2 +FC(F)(F)c1cccc(COCCn2cc(-c3ccncn3)cn2)c1 +COCCn1cc2c(n1)C(NC(=O)c1cc(C)n[nH]1)CCC2 +CCc1nc2n(n1)CCCC2NC(=O)NC1CCc2c(O)cccc21 +Cc1ccncc1NC(=O)NCc1cnc(OCC(C)C)c(Cl)c1 +CN(Cc1ccc(O)cc1)C(=O)NCCc1nccs1 +CCC(CC)C(=O)N1CCC(Oc2cccnc2)CC1 +Oc1ccc(F)c2c1CCNC2COCc1ccccc1 +Cc1cc(NC(=O)CNc2ccc(CC(=O)NC(C)C)cc2)on1 +COc1ccc(CCNC2=NS(=O)(=O)c3ccccc32)cc1OC +CCc1ccc(C(=O)Nc2ccc(S(=O)(=O)NCC3CC3)cc2)o1 +C=CCCCOc1cccc(NC(=O)c2cnn(C)c2)c1 +CS(=O)(=O)N1CCN(Cc2cscn2)CC1 +Cc1noc(C)c1C(C)NC(=O)c1ccnc(OC2CCC2)c1 +COC(=O)c1ccc(CNc2cncc(-n3cccn3)n2)cc1 +CCc1nc(CC(=O)NCCOc2cccnc2)cs1 +Cc1ccnc2nc(C(=O)Nc3sccc3C(N)=O)nn12 +O=C(Cn1nnc2ccccc21)NCCOc1ccccc1F +CCc1nc(CC(=O)N(CC(C)C)CC(F)(F)F)cs1 +Cc1nnsc1CN(C)Cc1cccc(-n2cccn2)c1 +CNC(=O)Cc1noc(-c2cccc(-c3ccoc3)c2)n1 +NC(=O)Cn1c(=O)n(Cc2ccco2)c(=O)c2ccccc21 +Cc1c(CN2CCOC(c3cccc(O)c3)C2)cc(C#N)n1C +CN(Cc1ccc(O)cc1)C(=O)c1cccc(N)c1 +CCOC(=O)c1cnc(CC)nc1-c1ccccc1OC +Cc1ccc(-n2nc(CO)c(C(=O)NC3CCCC3)n2)cc1C +CC(C)N(Cc1cnn(C)c1)S(=O)(=O)c1c[nH]c2ncccc12 +CC(C)C1(CNC(=O)N2CCCC(C3(C)OCCO3)C2)CC1 +CCN(CCO)C(=O)c1csc(-c2cccs2)n1 +CC(=O)NCCNC(=O)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +Cc1cc(NC(=O)CSc2nnc(C)n2Cc2ccccc2)no1 +CN(Cc1nc2ccccc2c(=O)[nH]1)Cc1c(F)cccc1Cl +CC(c1cccc(Cl)c1)n1c(N)cc(=O)[nH]c1=O +CCC(=O)N1CCCN(C(=O)c2cccc(N3CCNC3=O)c2)CC1 +CC(C)CNC(=O)C1CCCN(c2cnn(C)c(=O)c2)C1 +CCCc1cc(C(=O)Nc2ccc(S(=O)(=O)NC)cc2)[nH]n1 +N#CCC(COc1ccc(Cl)cc1)N1CCCCC1 +O=C(c1ccc2[nH]cnc2c1)N1CC(c2nc(-c3ccccn3)no2)C1 +Cc1nc(CNc2cccc(Cl)c2SC(F)F)no1 +COc1cccc(Nc2nc(N)nc(C(F)(F)F)n2)c1 +COCCCNc1cc(C(F)(F)F)ccc1F +Cc1ccc2c(CC(=O)N3CC(=O)Nc4cnccc43)c[nH]c2c1 +CC(C)c1nc(Cc2nc(-c3ccncc3)no2)cs1 +CSc1ccc(CNC(=O)COc2cccc(C)c2)cc1 +O=C(NCCc1ccccc1)C1COC(=O)N1Cc1ccncc1 +CCn1cc(NS(=O)(=O)c2ccc(F)cc2)ccc1=O +Nc1cccc(-c2nc(CCNc3ccc(C(F)(F)F)cc3)n[nH]2)c1 +Cc1nc(NC(=O)N2CCCN(c3ccccc3)CC2)nn1C +CCn1nnc2cc(C(=O)C(C#N)c3nc(C)cc(C)n3)ccc21 +CC(C)COC(=O)N1CCCN(C(=O)Nc2cccnc2)CC1 +COC(=O)c1c(C)[nH]c(-c2csc(N3CCOCC3)n2)c1C +COc1ccc(-c2csc(-c3cnccn3)n2)cc1OC +O=C(NCc1cccnc1)NCC1COc2ccccc2O1 +COc1ccccc1S(=O)(=O)NC1(C)Cc2ccccc2C1 +COc1ccc(C(C)C)cc1S(=O)(=O)n1cnc(C)c1 +COC(=O)c1ccc(CN(C)c2ccc(C#N)cn2)cc1 +N#Cc1ccc(Cl)c(NC(=O)CCc2nc(-c3ccoc3)no2)c1 +OCCn1cnc2cc(-n3ccnc3-c3cccc(Cl)c3)ccc21 +O=C(Cn1cccn1)Nc1cccc(C#Cc2ccccn2)c1 +COc1cc(C)c(C(=O)OCC(F)(F)F)cc1OC +COC(=O)c1ccc(C(=O)Nc2cc(C)ccn2)cc1 +CCN(Cc1ccccc1)C(=O)c1cc(N)ccc1Cl +COc1ccc(NC(=O)CSc2ncnn2-c2ccccc2)cc1 +CC(=O)N1CCCN(C(=O)CCc2nc(C(C)(C)C)no2)CC1 +CCn1cc(C(=O)N2CCOCC2)c2cc(OC)c(OC)cc2c1=O +Cc1ocnc1CNC(=O)Nc1ccccc1OC(C)C +Cc1csc(NC(=O)NCc2ccccc2Cl)n1 +O=C1CCc2c(OCc3nccn3C(F)F)cccc21 +O=C1CCC(C(=O)NCc2ccc(F)c(Cn3ccnc3)c2)N1 +CC1COCCN1C(=O)c1[nH]nc(C2CC2)c1N +Cc1csc(NC(=O)N(C)CCOc2ccccc2C)n1 +Cc1cc(NC(=O)C(C)Sc2ccccc2)n(C)n1 +Cc1cc(NC(=O)c2cnn(-c3ccncc3)c2C)ccn1 +COc1cc2ncc(C(=O)c3ccccc3O)cc2c(OC)c1OC +O=C(NCc1nc(-c2cccs2)no1)Nc1ccccc1 +Cc1ccc(OCC(=O)Nc2c(C)cccc2C(C)C)cn1 +COc1ccc2c(CC(=O)NCCS(N)(=O)=O)coc2c1 +NC(=O)N1CCCC(C(=O)OCC2CCCCC2)C1 +CN(C(=O)c1cccnc1)C1CCN(c2ccc(F)cc2)CC1 +N#CC1(NC(=O)Cn2nc3n(c2=O)CCCCC3)CCC1 +CCN(C(=O)CCNC(=O)OC(C)(C)C)c1ccccc1 +NC(=O)c1cnc(NC(=O)c2ccc(CN3CCCC3=O)cc2)s1 +CCSc1nc(N)nc(-c2cccs2)c1C#N +O=C(NCc1ccc(OCc2ccccn2)cc1)C1CC=CC1 +CNC(=O)CN(C)S(=O)(=O)c1cc(OC)c(OC)cc1F +CCC(CC)N(C)C(=O)c1ccc(N(CC)CC)nc1 +C=CCN1CCN(C)C(=O)C12CCN(c1ncc(F)cn1)C2 +Cc1ccc(CC(=O)NC(C)C(=O)N2CCOCC2)cc1 +CCOc1ccc(C(F)(F)F)cc1NC(=O)c1ccnnc1 +Cc1[nH]c2ccccc2c1C(=O)Nc1ccc(CC(=O)N(C)C)cc1 +O=C(NCC1COCc2c(-c3ccoc3)nnn2C1)c1ccsc1 +Cc1ccccc1C(=O)N1CCN(C(=O)OC(C)(C)C)C(C)C1C +COc1ccc(-c2n[nH]cc2C(=O)Nc2nnc(C(C)C)s2)cc1 +CC(C)(C)c1oc(C(N)=O)cc1Cn1c(=O)[nH]c2ccccc21 +CCC(CO)n1cc(O)c(=O)cc1CN1CCN(CCO)CC1 +CS(=O)(=O)N1CCCC(c2cc(=O)[nH]c(N)n2)C1 +CC1CN(C(=O)CCC(=O)NCC2CCCO2)c2ccccc2S1 +CNC(=O)c1cccc(C(=O)N2CC(C)Sc3ccccc32)c1 +O=C(CC12CC3CC(CC(C3)C1)C2)Nc1ccccn1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NCC(F)(F)F +CC(NC(=O)c1cn2c(n1)COCC2)c1ccc(F)cc1 +Cc1cc(C)n(-c2ccc(CN(C)Cc3ccc(C#N)cc3)cc2)n1 +CCNC(=O)c1ccccc1NC(=O)c1ccc(N2CCCC2)nc1 +N#Cc1cccc(NC(=O)Cn2nc(-c3cccs3)oc2=O)c1 +C=CCN(Cc1cccc(C#N)c1)C(=O)Cc1csc(C)n1 +CCn1c(SCCc2ccc(OC)cc2)nnc1N1CCOCC1 +CC1CCCCN1C(=O)CN1CCN(c2ncccc2C(N)=O)CC1 +CC1(C(=O)Nc2nccs2)Oc2ccccc2N=C1O +Cc1cc2cc(NC(=O)N(CCO)C3CCCCC3)ccc2[nH]1 +CCN(CC)C(=O)c1cnn(-c2ccccc2)c1-n1cccc1 +CN(C(=O)c1ccccc1F)c1ccc(C(N)=O)cc1 +CC(=O)c1cccc(OC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)c1 +Cc1cncc(NC(=O)NC(C)c2ccc(-n3ccnc3C)cc2)c1 +N#CC1(NC(=O)c2ccc(-c3ccccc3)cc2)CCOCC1 +CC(C)Oc1ccc(CNC(=O)Nc2ccnn2C(C)C)cc1 +COc1ccc(CCC(=O)NC(C)(C)CO)cc1OC +CC(C)Sc1ccccc1C(=O)Nc1ccc(CNC(N)=O)cc1 +CCN(C(=O)Cc1c(F)cccc1F)C(C)c1cccnc1 +CC(C)(C)C(=O)Nc1nnc(-c2ccsc2)o1 +CCn1cnnc1CNC(=O)c1cnn(-c2ccc(Cl)cc2)c1 +O=C(Nc1ccc(Br)cc1)c1ccoc1 +CC(NC(=O)Cc1cccc(F)c1)C1CCCO1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)CN1CCOCC1C1CC1 +Cc1cc(-c2cnc(C)nc2-c2ccoc2C)on1 +O=C(Nc1ccnn1C1CCCCC1)c1cnc(C2CCCO2)s1 +O=C(NCC(=O)N1CCc2ccc(Cl)cc2C1)c1cccs1 +COc1ccc(C(=O)N2CCCCC2)cc1Br +Cc1ccc(N(CCC#N)C(=O)C(C)Sc2ccccn2)cc1 +CN(Cc1cccnc1)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +CCN(Cc1ccc(OC)cc1)C(=O)c1ccc(OC)c(OC)c1 +COc1ccccc1C1(CNC(=O)c2ccn(C)c(=O)c2)CCCC1 +O=C(OCCn1nc2ccccn2c1=O)c1ccn(-c2ccccc2)n1 +CNc1cc(C(=O)N(C)Cc2n[nH]c3c2CCCCC3)ccn1 +CCOC(=O)C1=C(CN2CCOc3cc(F)ccc32)NC(=O)NC1 +Cc1ccc(NC(=O)COC(=O)c2cccc(N)c2)cc1C +CN(Cc1cc(Cl)cc(Cl)c1)C(=O)c1csnn1 +COc1ccc(OCC(=O)Nc2oc(C)c(C)c2C#N)cc1 +Cc1sc(=O)n(CC(=O)NC(C)COc2ccc(F)cc2)c1C +C#CC(C)(CC)NC(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +Cn1c(CCNC(=O)c2n[nH]c3ccccc23)nc2c(F)cccc21 +NC(=O)C1CCN(C(=O)COCc2ccccc2Cl)CC1 +O=C(Cn1c(C2CC2)nc2ccccc21)N1CCOCC1 +CCOCCC(=O)N1CCCc2cc(C(C)C)ccc21 +COc1cc(Cl)ccc1CNC(=O)Nc1ccc2c(c1)COC2 +COc1ccc(CCNC(=O)c2ccoc2)c(OC)c1 +Cc1ccc(N2CCC(Nc3ccc4c(c3)C(=O)NCC4)C2=O)cc1 +FC(F)(F)Oc1ccccc1CNc1cccnc1 +O=C(c1n[nH]c2ccccc12)N1CCCC1c1noc(C2CC2)n1 +Cc1cc(C(=O)Nc2cccc3cnccc23)no1 +Cc1cc(F)ccc1C(=O)NCc1nnc(C2CCC2)n1C +CCCOC(=O)c1cc(N)ccc1Sc1ncn[nH]1 +COc1cc2c(cc1F)C(COc1ccccc1)NCC2 +Cc1cnn(CC2CCCCN2C(=O)c2ccsc2)c1 +Clc1ccc(-c2nc(C3CCOC3)no2)cc1 +CCCCC(=O)NCC(O)(c1ccccc1)C1CC1 +CCN(CC)C(=O)c1cccc(NC(=O)COc2ccccc2F)c1 +O=C(Nc1ccc(F)c(F)c1)c1nnn(-c2ccc(F)cc2)n1 +c1cnc(N2CCOC3CN(Cc4nccs4)CC32)nc1 +NS(=O)(=O)c1ccc(C(=O)Nc2ccc(-n3ccnc3)nc2)cc1 +CCCNc1nc(-c2sc(C)nc2C(C)C)cs1 +COc1ccc(-c2csc(-n3nc(C)cc3C)n2)cc1 +COC(=O)CCN(C(=O)c1cnc(C2CCCO2)s1)C(C)C +Cc1nc2cc(CC(=O)N3CCn4c(C(N)=O)cnc4C3)ccc2[nH]1 +CCCC(=O)N1CCCC1C(=O)Nc1ccc(F)cc1Cl +CC(NC(=O)NCC(=O)NC1CC1)c1ccc(F)c(Cl)c1 +COc1cccc(C(=O)NCCC(=O)Nc2ccccc2C#N)c1 +CC(NC(=O)C1COCCO1)c1ccc(NC(=O)NC2CC2)cc1 +Cc1cc(C(C)NC(=O)Nc2nnc(-c3ccsc3)s2)c(C)o1 +Cc1cc(C(=O)Nc2cc(C)nn2-c2ccccc2)on1 +O=C1NCCN1C1CCN(S(=O)(=O)c2cn[nH]c2)CC1 +COCC(NC(=O)c1cc(C)n(C)n1)c1cccc(C(F)(F)F)c1 +CCNC(=O)NCCc1c[nH]c2ccc(Cl)cc12 +CC(Oc1ccc2ccc(=O)oc2c1)C(=O)Nc1ccc(F)cc1 +Cc1cc(=O)oc(C)c1C(=O)NC1CCCCCC1 +CC(C)CC(=O)Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3 +CC(=O)N(C)c1ccc(NCc2cccc(-c3cccnc3)c2)cc1 +CSc1ccc(C(=O)NCc2cccc(-c3nc(C)n[nH]3)c2)cc1 +O=C(NCc1ccccc1)c1cc2ccccc2oc1=O +CCCCC1C=CCN1C(=O)Cn1cnc2ccsc2c1=O +COC(=O)c1ccc(NC(=O)N2CCN(S(C)(=O)=O)CC2)cc1 +CCCCC(=O)Nc1ccc(Cl)c(C(=O)NC)c1 +Cn1ccc(C(=O)N2CCc3ccccc32)cc1=O +CCCOc1ncccc1CNC(=O)Nc1cc(F)ccc1OC +CC(C#N)(NC(=O)CN1CCOC(c2nccs2)C1)C1CC1 +CN(C)S(=O)(=O)NCC(O)c1ccc2c(c1)CCC2 +CCCNC(=O)C(C)S(=O)(=O)c1nncn1C(C)C +COc1ccc(NC(=O)C2CCCN(c3cn[nH]c(=O)c3)C2)c(C)c1 +CCc1cc(=O)oc2cc(OCC(=O)N(CC)CC)ccc12 +Cc1cccc(-c2cc(N3CCC(C(=O)NC4CC4)CC3)ncn2)c1 +CCCCc1ccc(NC(=O)c2cc(S(N)(=O)=O)oc2C)cc1 +CCCc1nnc(NCc2ccc(OC)c(F)c2F)o1 +Cc1cc(C(=O)COC(=O)c2cccn2C)c(C)n1CC1CCCO1 +CC(=O)NC1CN(c2cnc3ccccc3n2)CC1c1ccc(C)o1 +CC(C)(CNC(=O)CCn1ccnn1)c1cccc(C(F)(F)F)c1 +O=C(CN1CCOC(Cn2cncn2)C1)N1CCCC2CCCCC21 +Nc1nc(N)nc(SCC(=O)NC2CCCc3ccccc32)n1 +CC(C)NS(=O)(=O)c1cccc(CNS(C)(=O)=O)c1 +Cc1cc(C)c(NC(=O)C2(N3CCC3=O)CCCCC2)c(C)c1 +CC1c2ccsc2CCN1CC(=O)Nc1nccs1 +CCn1nc(C)cc1C(=O)Nc1cc(-c2cc(C)cc(C)c2)n[nH]1 +O=C(NC1CC(=O)N(Cc2ccc(F)cc2)C1)c1ccc(Cl)cn1 +CCCOc1cccc(CNC(=O)CN2CCN(C(C)=O)CC2)c1 +O=C(Oc1ccc(C(F)(F)F)cc1)c1ccoc1 +CC(NS(=O)(=O)c1ccccc1OC(F)(F)F)c1ccncc1 +O=C(COc1ccc2c(c1)OCO2)Nc1nccs1 +C#Cc1cccc(N(C(=O)c2ccc(N3CCCC3=O)cc2)C(C)C)c1 +CCOCCC(=O)Nc1ccccc1C(=O)N1CC(C)CC(C)C1 +CCc1c(C)nc(N)n2c(SCC(=O)c3ccccc3F)nnc12 +CCc1nc(CN2CCN(S(C)(=O)=O)CC2)cs1 +COCC(=O)N1CCCn2nnc(Cn3cccc3)c2C1 +COc1cccc(CNC(=O)c2ccnc3ncccc23)c1 +CCOC(=O)CC(NC)C(=O)c1ccc2c(c1)CCCC2 +CNC(=O)C1Cc2ccccc2CN1S(=O)(=O)c1c(C)noc1C +CCc1nc(CC(=O)NC(CC)c2cccc(Cl)c2)cs1 +Cc1cc(NC(=O)Cc2nc(-c3cccs3)oc2C)ccn1 +Cc1cc(C(=O)Cn2cc(Cl)cn2)c(C)n1Cc1ccccc1 +Cc1nc(C#N)c(C#N)n1Cc1ccc(CO)cc1 +CC(C)NC(=O)Nc1ccc(C(=O)Nc2ccccc2O)cc1 +O=C(Cn1nc2ccccn2c1=O)Oc1ccc2ccc(=O)oc2c1 +CCc1ccc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)o1 +CC1Cc2ccccc2N1C(=O)c1ccc(N2CCOCC2)nc1 +CN(C)c1ccc(Cl)cc1NC(=O)C1CCCN(C(=O)C2CC2)C1 +COc1ncccc1NC(=O)c1cc2ccccc2c(OC)n1 +O=C1CN(C(=O)Nc2ccc(Cl)c(Cl)c2)CCN1 +Cc1cc(N)nc(SCC(=O)NC(C)CCC(C)C)n1 +CC(C)n1nc(-c2cncc(Br)c2)c2c1CCNC2 +O=C(COc1cccc2cccnc12)NC1CCCCC1 +CN(C)c1ccc(C#CCNC(=O)c2ccsc2)cc1 +Cc1n[nH]c(C)c1S(=O)(=O)Nc1cccc(-n2cnnn2)c1C +O=c1c2cnn(-c3ccccc3)c2nnn1Cc1nccn1C(F)F +O=C(NCc1cccc(OCC2CCC2)c1)c1cnn2ncccc12 +Cc1ccc(S(C)(=O)=O)cc1C(=O)NC1CC2CCC1(C)C2(C)C +O=C(CCOc1ccccc1F)Nc1cccc2c1OCCO2 +Nc1cccc(-n2cc(-c3cc(F)ccc3F)nn2)c1 +CC(=O)c1cc(Br)ccc1OCC(=O)NC1CC1 +O=C(Nc1cc(F)c2nc(N3CCOCC3)ccc2c1)C1CCCC1 +Cc1ccc(CC(=O)Nc2ccccc2OC(C)C#N)s1 +CC(=O)c1ccc(NC(=O)C(C(C)C)N2CCCC2=O)cc1Cl +CCCC1CN(C(=O)c2cccc(N3CCCC3=O)c2)CCO1 +COC(=O)CN1CCc2c(c(N)cc(OC)c2OC)C1 +CC(=O)N(Cc1ccc(NC(=O)NCC(C)C)cc1)C1CC1 +CN(C(=O)c1cccc(N)c1)c1ccc(F)c(F)c1 +CCCC(=O)N1CCc2nc(NC(=O)c3ccccn3)sc2C1 +CCN(CC)C(=O)c1ccc(Nc2ncnc3ccccc23)cc1 +COc1cccc(N2CC(C(=O)Nc3nc(C)cs3)CC2=O)c1 +CN(Cc1cccs1)C(=O)CCC(=O)N1CCOc2ccccc21 +O=C(Nc1cc(N2CCOCC2)ncn1)c1c(F)cccc1Cl +COCCn1cnnc1C1CN(C(=O)C2CCC2)C1 +CC(=O)c1cnc(NCCc2nc3ccc(C)c(C)c3[nH]2)nc1C +COC(=O)c1cc(-c2ccc(C(F)(F)F)cc2OC)on1 +COCC(C)NC(=O)N(C)Cc1ccc(OC)cc1 +CCCNC(=O)CNC(=O)c1nc2ncc(Br)cn2n1 +CC(O)CN(C(=O)NCc1ccnc(OC(C)(C)C)c1)C(C)C +O=C(OCc1nc(-c2cccc(Cl)c2)no1)C1CCOCC1 +CC(C)CS(=O)(=O)N1CCC(OCc2ccc(F)cc2)CC1 +N#Cc1cccc(C(=O)N2CC(c3nc(-c4cccnc4)no3)C2)c1 +CC1(C(=O)Nc2ccc(-n3cnnn3)cc2)CC1(Cl)Cl +CC1CCN(C(=O)C(C)NC2CCN(S(C)(=O)=O)CC2C)CC1 +CCCN(CC1CC1)C(=O)Nc1cnc2c(c1)c(=O)n(C)c(=O)n2C +O=C(NC1CC1)c1ccc(-c2cccc(-c3cc[nH]n3)c2)o1 +CCOC(=O)C(C)NS(=O)(=O)c1c(C)noc1C +CCn1c(=O)n(CC)c2nc(NC(=O)CCC(=O)NC(C)C)ccc21 +CC(=O)NCC(=O)N(Cc1ccc(Cl)c(Cl)c1)C1CC1 +O=C(Nc1ccccc1-n1ccnc1)c1ccc(F)cc1Cl +C=CCNc1ncc(C(=O)NC2CCCCC2CO)s1 +Cc1c(C(=O)N2C(C)COCC2C)oc2c(C)cccc12 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)Nc1ccccc1O +CCCc1nc(NC(=O)CN(C)C(C)=O)sc1CC +Cc1nn(-c2ccccc2)c(C)c1COC(=O)C(C)C +Cc1ccnc(NC(=O)c2cnc(-c3ccccn3)nc2N)c1 +CC(=O)N(C)c1ccc(NC(=O)c2csc3c2CCCC3)cc1 +CNS(=O)(=O)c1ccc(C)c(NC(=O)c2ccc[nH]2)c1 +Cc1nc(C2CCCN(Cc3cccc(F)c3)C2)[nH]c(=O)c1C +COCC(O)CN1CCN(CC(=O)NC2CCCC2)CC1 +COC(=O)c1cc(CNC(=O)NCc2ccco2)ccc1OC +Cc1nc(NC(=O)C2CCC(=O)N2Cc2cccs2)sc1C +CNC(=O)c1cccc(CNc2cc(F)ccc2Cl)c1 +Cc1cc(=O)n(C)cc1NC(=O)CCOC(C)CC(C)C +Cc1nc(-c2c[nH]c(C(=O)NCc3cccc(Cl)c3)c2)cs1 +O=C(OCC(F)(F)F)c1cc(-c2ccc(F)cc2)[nH]n1 +COc1ccc(C(C)N(C)S(=O)(=O)c2ccc(F)cc2)cc1 +O=C(NC1CC1c1ccccc1)C1CC1c1ccccc1 +CN(Cc1cccc(F)c1)c1ncnc2ccc(F)cc12 +N#CCCn1cnc2cc(Br)cnc21 +CC(CO)C(C)NC(=O)Nc1ccc(N2CCCC2=O)cc1 +CN(C)c1cccc(C(=O)NC2(C)Cc3ccccc3C2)c1 +CCCCNC(=O)Cn1c(-c2ccccc2)nc(C)cc1=O +O=C(CCCn1cccc1)NCCc1c[nH]c2ccccc12 +CC(=O)c1ccccc1NC(=O)COC(=O)c1cnc2ccccc2n1 +COc1ccc(CNC(=O)Nc2ccc(F)c(Cl)c2)cn1 +COCc1cccc(C(=O)Nc2ccc(C#N)c(Cl)c2)c1 +Cc1nn(C)c2sc(C(=O)N(C)Cc3ccccn3)cc12 +CC(C)(C)c1ccc(OCc2cc(N)n(CCO)n2)cc1 +COc1ccc(CC(=O)NC2CCCCNC2=O)cc1 +CN(Cc1csc2ccccc12)C(=O)c1cccc2cn[nH]c12 +CCCc1c(CO)nnn1-c1ccc2c(c1)CCC2 +CCCCCNC(=O)Nc1ccc2c(c1)NC(=O)CS2 +CC(=O)NC(C(=O)N1CCCC1c1c(C)nn(C)c1C)C1CCCC1 +COc1cc(NC(=O)c2cccc(C)c2C)ccc1NS(C)(=O)=O +Cc1ccc(CC(=O)N2CCN(CC(=O)NCC3CCC3)CC2)cc1 +O=C(Cn1cnc(-c2ccccc2)cc1=O)Nc1ccc(F)cc1F +CC(=O)Nc1ccc(CC(=O)N2CCOCC2CC(C)C)cc1 +CN(CC(=O)NCc1cnn(C)c1)C(=O)c1ccco1 +O=C(NCc1ccc2c(c1)OCO2)c1ccc(-c2cscn2)cc1 +CC(Cc1ccccc1F)NC(=O)c1n[nH]c(=O)[nH]1 +CN1C(=O)COc2ccc(C(=O)C3CCCCN3)cc21 +Cc1ccnc2nc(C(=O)N(Cc3ccccc3)c3ccccn3)nn12 +CCOc1nc(C)nc2c1nnn2Cc1ccccc1 +O=C(c1ccc(F)cc1F)N1CCN(c2n[nH]c(=O)[nH]c2=O)CC1 +COc1cccc(CNC(=O)Cn2nc(C)c(C#N)c2N)c1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(C2CC2)[nH]n1 +COc1cc(Br)c(NC(=O)NC(C)C2CC2)cc1OC +CN(Cc1cnn(-c2ccccc2)c1)C(=O)Nc1ccc(CC#N)cc1 +COc1ccc2c(=O)n3nc(N(CCO)CCO)ccc3nc2c1 +CC(C)C(C#N)NC(=O)CCS(=O)(=O)N1CCOCC1 +CN(Cc1ccncc1)C(=O)NCc1ccccc1OC(F)(F)F +CCC(C)NC(=O)Nc1ccccc1C(=O)N1CCCCC1 +CCOC(=O)c1ccc(NS(=O)(=O)N2CCCCCC2)cc1 +COc1cccc(OCC(=O)N=c2sccn2C)c1 +COc1ccc(Cc2cn3ccc(C)c(N)c3n2)cc1 +CCn1nc(C(=O)NCc2ccccc2Cl)c(=O)c2ccccc21 +Cc1cc(C)n(-c2cc(O)c(-n3nc(C)cc3C)cc2O)n1 +CC(C)CCNC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +CC1CC(C)CN(C(=O)c2ccc(C(C)C)nc2N)C1 +N#CCCN(CCC#N)C(=O)c1cccc(C(N)=O)c1 +COc1ccc(F)cc1NC(=O)NCC(C)(C)CC(C)O +CC(=O)Nc1cccc(NC(=O)CSc2ncc3ccccn23)c1 +CCCCNC(=O)Oc1ccccc1N1CCCC1=O +O=C(CSc1ccncc1)OCc1ccc(F)cc1 +Cc1cc(NC(=O)C2CCN(C(=O)c3c(C)oc(C)c3C)CC2)no1 +Nc1ccc(Cl)cc1C(=O)OCCc1cccnc1 +OCC(Nc1ccc(Br)cc1)C1CCOCC1 +CCc1cccc(C)c1NC(=O)N(C)C1CCOC(C)(C)C1 +Cc1nnc(SCC(=O)NCc2ccc(Cl)cc2)n1N +O=C(COc1nnc2ccccn12)Nc1cccc(Br)c1 +COc1cccc(NC(=O)N2CC3(COC(C)(C)OC3)C2)c1 +CC1(C)OCC2(COC(c3ccsc3)N2)CO1 +C#Cc1cccc(NC(=O)CN(C)C(=O)CC(C)C)c1 +CCOc1cc2c(cc1NC(=O)N1CCOC(C)(C)C1)OC(C)C2 +Cc1noc(C)c1CCCNC(=O)NCCc1cn2ccccc2n1 +CCC(CO)NC(C(=O)OC)c1ccc(Cl)cc1 +COCCN1CC(C(=O)Nc2cccc(Br)c2)CC1=O +Cc1ccc(C(O)c2cc3c(cc2NC(=O)C2CC2)OCCO3)cc1 +N#Cc1cccc(NC(=O)C(C#N)c2nc3ccccc3s2)c1 +O=C(Cc1csc(NC(=O)c2ccco2)n1)Oc1ccc(F)cc1 +CN(C)C(=O)CCc1nc(C2CCCC2)nn1C +O=C(NC1CCCCCC1)c1cccc2ccnn12 +Cc1cc(NC(=O)NCC2CCOC2C(C)C)c2ncccc2c1 +Cc1noc(C)c1C(C)NC(=O)N(C)CC(C)c1nccs1 +OC1CCN(c2cc(C(F)(F)F)nc(-c3ccncc3)n2)C1 +CCOC(=O)Nc1ccc(NCC2CCOC2)cc1 +CCc1noc(C2CCN(C(=O)c3ccc4c(c3)OCO4)CC2)n1 +CCCOc1ccc(Oc2ccc(C#N)cn2)cc1 +CS(=O)c1ccc(C(=O)OCCn2nc3ccccn3c2=O)cc1 +CC(Sc1nncs1)C(=O)c1ccc(NS(C)(=O)=O)cc1 +CC(C)CNC(=O)C(NC(=O)c1cnc2c(c1)NC(=O)CO2)C(C)C +N#Cc1ccc(NC(=O)C2CC2c2ccc(F)cc2)cc1 +CCCNC(=O)CNC(=O)NC(C)c1ccc(F)cc1Cl +Cc1cc2c(cc3c(=O)n(CC(=O)NC(C)(C)C)nc(C)n32)s1 +Cc1ccoc1C(=O)NC1CC(=O)N(CCc2ccc(F)cc2)C1 +Cc1csc2nc(Cn3cnc4sccc4c3=O)cc(=O)n12 +CC(C)n1ccc(CC(=O)NCc2ccnc(OC3CCCC3)c2)n1 +CCNC(=O)C(C)NC(=O)c1cc(COc2ccccc2F)[nH]n1 +CC(C)COC1CCN(C(=O)C2Cc3ccccc3O2)CC1 +CCOC(=O)c1cn2ccc(Br)cc2n1 +O=C(NCCC(=O)N1CCC2(CC1)OCCO2)c1ccco1 +CC(C(N)=O)N1CCN(Cc2cnc3cnccn23)CC1 +Cc1ccc(CNC(=O)C2CCCc3ccccc32)cn1 +CC(Oc1ccccc1)C(=O)NCCc1c[nH]c2ccccc12 +CN(c1c(F)cccc1F)S(=O)(=O)c1cccc(N)c1 +O=C(Cn1cnnn1)Nc1ccnn1Cc1ccc(Cl)c(F)c1 +CCn1cc(NC(=O)NCc2ccc(C)cc2)cn1 +Nc1cc(-c2nccnc2N2CCCC2)c2cc[nH]c2n1 +N#Cc1ccc(F)c(C2NCCc3cc(F)ccc32)c1 +Cc1cccc(OCCCNC(=O)C(C)(C)C#N)c1 +O=C(NCc1nnc2c(Cl)cc(C(F)(F)F)cn12)C1CCCC1 +COc1ccc(C(C)NC(=O)N2CC(C)OC(C)C2)cc1F +Nc1ccc(Sc2ncn[nH]2)c(C(F)(F)F)c1 +CCCC(C)NC(=O)C1CC(=O)N(c2ccc(C)cc2)C1 +C=Cn1ncc(CN(Cc2cccc(F)c2)CC2CCCO2)c1C +CCCNC(=O)Cn1nnc(CO)c1-c1ccc(C)c(C)c1 +CSc1ccc(NC(=O)N2CCCC2)cc1Cl +CCn1nc(C)cc1C(=O)NC1CCc2c(O)cccc21 +CCOC(=O)c1c(N)n[nH]c1NC(=O)c1ccc(F)cc1 +O=C(NCc1ccccc1CN1CCOCC1)Nc1ccccc1 +O=C1OCC2=C1C(c1ccc(F)cc1)c1cc3c(cc1N2)OCO3 +CC(=O)N1CCC(C)(c2nc(C)cc(C(=O)N3CCOCC3)n2)CC1 +CNc1nnc(SCC(=O)Nc2ccccc2C(=O)OC)s1 +CCNS(=O)(=O)c1ccc2c(c1)N(C(=O)C1CC1)CC(C)O2 +C#CCN(C(=O)CNC(=O)OC)C1CCCCC1 +Cc1cc(OC(C)C(=O)Nc2c[nH]nc2C)ccc1Cl +CC(C)C(=O)NCCn1ccc(-c2ccccn2)n1 +CCn1c(-c2cccs2)nnc1S(=O)(=O)CCc1ccccc1 +CC1CN(Cc2ccc(Cl)c(C(F)(F)F)c2)CC(C(N)=O)O1 +CC(=O)Nc1ccc(F)c(C(=O)N2CCC(Nc3ccccc3)C2)c1 +COc1ccc(C)cc1CC(=O)Nc1ccccc1F +Nc1cc(-c2cccs2)nn(CC(=O)Nc2cccc(F)c2)c1=O +Cc1ccccc1S(=O)(=O)N(CCO)C1CCCCC1 +COCC(=O)N1CCN(C(=O)c2sccc2C)CC1 +COC(=O)C(C)(C)NC(=O)c1cc(F)c(F)cc1Cl +O=C1CC(c2ccc(F)cc2)c2c(n3ccsc3nc2=O)N1 +CC(C)OCCCNC(=O)C(N)c1ccc(N)cc1 +CCN(CC)C(=O)CCC(=O)Nc1cc(F)ccc1OC +COc1cc(F)cc2sc(NC(=O)CN(C)S(C)(=O)=O)nc12 +O=C(NCCC1CC1)N1CCC(OCc2ccccc2F)CC1 +Cc1c(C(=O)Nc2cccc(Cl)c2)nnn1-c1ccccc1 +CCN(Cc1cnc(C)s1)C(C)c1ccc(F)cc1 +O=C1CN(S(=O)(=O)c2ccc(C3CCCCC3)cc2)CCN1 +CS(=O)(=O)NCC(=O)N1CCCC1c1ccncc1 +Cc1cnc(C(=O)NC2CCN(c3ccccc3F)C2=O)cn1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(NC(C)=O)cc2)cc1 +CC(C)N1CCN(C(=O)C2CCOc3ccccc32)CC1 +Cc1nc(C(=O)NCc2ccc(F)c(C)c2)cs1 +O=C(OCC(=O)N1CCOCC1)c1cc2ccccc2cc1O +CNC(=O)CC(c1cc(F)ccc1OC)C1CC1 +Nc1ccc(C(=O)Nc2nc3c(s2)CCC3)nn1 +CC(C)NC(=O)COC(=O)Cc1ccccc1F +O=C(Cc1cc2ccccc2s1)N1CCOCC1 +CC1CCN(C(=O)CCc2nc3ccccc3c(=O)[nH]2)CC1 +CC(C)c1nc(CS(=O)(=O)c2ccccc2)no1 +CC(=O)c1cccc(OC(C)C(=O)Nc2c(F)cccc2F)c1 +C=CCn1c(N)c(S(C)(=O)=O)c2nc3ccccc3nc21 +C=CCN(CC(F)(F)F)C(=O)c1ccc2c(c1)NC(=O)CCS2 +Cn1c(NCCCOCc2ccccc2)c(C#N)c(=O)n(C)c1=O +O=c1c(CO)ccc(-c2ccc(F)cc2)n1C1CCCC1 +Cc1ccc(NC(=O)c2ccc(OC(C)C)cc2)c(N)c1 +COCC(=O)N1CCCC1c1nc(C)cc(Oc2ccccc2C)n1 +CCCCS(=O)(=O)NCc1ccc(C)cc1N(C)C +Cc1csc(CN(C)Cc2cc(F)cc(F)c2)n1 +O=C(CCNC(=O)c1ccc(O)c(Cl)c1)NCc1ccccc1 +Cc1nn(-c2ccccc2F)c(C)c1C1COCCN1C(N)=O +O=C(c1cc(C(F)(F)F)n[nH]1)N1CCN(c2ccccc2)C(=O)C1 +O=C(NCc1ccoc1)C12CC3CC(CC(C3)C1)C2 +CCNC(=O)NC1(C(=O)Nc2ccc3nc(C)oc3c2)CCCC1 +Cc1cc2c(cc1F)C(c1ccc(F)cn1)NCC2 +COC(=O)C(NC(=O)C1CCCO1)c1ccccc1 +O=S(=O)(NCC1(O)CCCC1)c1cccc2ccccc12 +O=S(=O)(c1ccc(Cl)cc1)N1CCn2c1nc1ccccc12 +CC(C)COc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +CCC(C)n1nccc1NC(=O)Cc1c(C)noc1C +Nc1ccc2onc(CC(=O)Nc3ncccn3)c2c1 +CCc1nnc(NC(=O)CNC(=O)C2CCCCC2)s1 +Cc1cccc2c1cnn2CCCNS(=O)(=O)c1ccccc1 +CCc1nnc(CN2CCN(c3nc(C)cs3)C(C)C2)o1 +O=C(NCCCCN1CCOCC1)N1CCCC1c1ccc(F)cc1 +CCC(=O)c1ccc(S(=O)(=O)CC(O)CO)cc1 +CNc1cc(C)nc2c(C)c(-c3ccc(C)cc3)nn12 +CC(C)C(=O)N1CCN(c2ccccc2F)CC1 +Cc1ccn2c(=NC(=O)c3cc(=O)c4ccccc4o3)[nH]nc2c1 +O=C1CN(C(=O)Cc2ccc3c(c2)CCC3)CCN1 +O=c1cc(C2NCCc3c(Cl)cccc32)cc[nH]1 +CN(CC(=O)Nc1ccccc1)C(=O)Nc1ccc(C#N)cc1 +CCc1nnc(NS(=O)(=O)c2ccc(OC)cc2)s1 +Cc1cc(C(=O)OCCn2cccn2)c(C)n1C1CC1 +N#Cc1ccc(Cl)cc1NC(=O)CSc1nnc2ccccn12 +Cc1cccc(C)c1NC(=O)CCCSc1ncccc1Cl +Cc1cccc(NC(=O)c2cnn(C(=O)c3ccccc3)c2N)c1 +COC(=O)C1CCCCCC1NS(=O)(=O)Cc1cccc(F)c1 +Cc1cccc(C)c1OCCCNC(=O)c1ccncc1F +O=C(Nc1ccccc1Cl)c1cc(-c2cccnc2)[nH]n1 +COCCOCC(=O)Nc1ccc(F)cc1-c1ccc(Cl)cc1 +O=C(CC1OCOC1c1ccccc1)OCC(=O)c1ccccc1 +CCC1(CC)C(NC(=O)NCc2ncn(C)n2)CC1OC +Cc1nc(C(=O)Nc2ccc(C(N)=O)c(Cl)c2)cs1 +CC(C)n1cnnc1SCC(=O)NCc1ccoc1 +O=C(c1cccnc1)N1CCC(c2ncncc2-c2ccncc2)CC1 +O=C(CNC(=O)c1ccco1)Nc1ccc2ccccc2c1 +COc1ccccc1OCC(=O)N1CCc2ccc(N)cc2C1 +Cc1ccc(C)c(C(=O)Nc2cc(C(=O)N(C)C)ccc2Cl)c1 +OCCOc1ccc(NCc2cccc3[nH]ccc23)cn1 +CNC(=O)CCC(O)c1ccc2c(c1)OCCO2 +O=C(Cc1cccc(O)c1)N1CCN(C2CC2)CC1 +CSc1ncnc(Nc2cccc(CN3CCOCC3)c2)c1C#N +CC(Oc1ccccc1Cl)C(=O)NCc1nnc2n1CCC2 +Cc1ccc(CNc2ccc(C#N)c(C#N)c2)s1 +COc1ccc(-c2noc(-c3ccc(CNC(C)=O)s3)n2)cc1 +O=C(c1scnc1C1CC1)N1CCOc2ccc(F)cc21 +C=CCCC(=O)Nc1ccc(C)c(S(=O)(=O)NC2CC2)c1C +NC(=O)Cn1ccnc1Cc1ccc(F)cc1F +CCc1cccc2c(N3CCN(CCO)CC3)c(C#N)cnc12 +O=C(CS(=O)(=O)c1ccccc1F)N1CCCCCC1 +CCOC(=O)C1CC(=O)N(c2ccc(C(C)C)cc2)C1 +COCCNC(=O)Nc1cccc(C(=O)N2CCc3ccccc32)c1 +CC1(C)CN(Cc2cn(-c3ccccc3)nc2-c2cccnc2)CCO1 +Clc1ccccc1C1CN(Cc2cnc3cnccn23)CCO1 +CS(=O)(=O)N1CC(OCc2cccc(F)c2)C1 +O=C(Nc1ccc(N2CCOC2=O)cc1)C1CC=CC1 +CC(O)(CNC(=O)Cc1ccc(F)cc1)c1cccs1 +Nc1cccc2oc(=O)n(CCCc3ccccc3)c12 +CCc1cc(N(C)CC(c2cccs2)N2CCOCC2)ncn1 +CCC1CCCCN1C(=O)CNC(=O)c1cc(OC)cc(OC)c1 +Cc1cc(C(=O)NC(C)C)nc(N2CCCCCC2)n1 +COC(=O)CN(c1ccc(Cl)c(Cl)c1)S(C)(=O)=O +CC(Oc1ccc(S(C)(=O)=O)cc1)C(=O)c1c[nH]c2ccccc12 +Cc1cc(C)c(C(=O)NCC(NC(=O)c2oc(C)cc2C)C(C)C)o1 +CC(Oc1ccc2ncccc2c1)C(=O)n1ccnc1 +Cc1cc(CN(C)C(=O)Nc2cccc(OC(F)F)c2)no1 +CCc1nc(CC(=O)Oc2ccc(NC(=O)OC)cc2)cs1 +CCc1ccc(CNC(=O)C2CCC(=O)N2C2CCCC2)cc1 +COC(=O)CSc1nc(C(F)(F)F)nc2ccccc12 +CC(C)n1cnc(S(=O)(=O)N2CCCC(Cn3cncn3)C2)c1 +O=C(NCCc1ccccc1)c1cc2ccccc2[nH]c1=O +CCn1nnc2c(=O)n(CC(=O)N(C)c3ccccc3)cnc21 +Cc1cc(NC(=O)Cn2nnc3ccccc32)nn1Cc1ccccc1 +CCCCNC(=O)C(C)Sc1nnc(N2CCOCC2)s1 +Cc1cnc(C(=O)NC(C)c2nc3ccccc3[nH]2)cn1 +Cc1ccc2nc(NC(=O)CN3CC(C)OC(C)C3)sc2c1 +O=C(c1ccoc1)N1CCC(O)(c2cccc(C(F)(F)F)c2)CC1 +COc1ccccc1OCCC(=O)NCc1ccncc1 +COC(=O)C(NC(=O)CCc1cccc(F)c1)C(C)C +COc1ccc(-c2ncc(C(=O)NCc3ncc[nH]3)s2)cc1 +COCCN(Cc1ccsc1)S(=O)(=O)c1cccc(Cl)c1 +CCCn1nnc(C#N)c1-c1ccc(C(F)(F)F)cc1 +Cn1nc(Oc2cc(Cl)ccc2Cl)c(=O)n(C)c1=O +CN1CCOC2(CCCN(S(=O)(=O)c3ccccc3)C2)C1 +O=S(=O)(c1ccc2c(c1)N=C(O)CS2)N1CCCCCC1 +CC(=O)c1ccc(NC(=O)C2CCCN2C(=O)C2CCCC2)cc1C +COc1ccc(CNC(=O)N2CC(c3nc(C)no3)C2)cc1 +NC(=O)c1ccc(C#CCNC(=O)CCC2CCCC2)cc1 +Cc1cccc(C(=O)NCC(=O)Nc2ccncc2)c1 +Cc1cc2nc(-c3ccccc3)cc(N3CCCNC(=O)C3)n2n1 +N#Cc1cccc(NC(=O)C2CC2c2ccco2)c1 +CC(C)N(CCCO)C(=O)CN1CCCCCC1=O +COC(CNC(=O)c1ccccc1SC)c1ccccc1C +COc1ccc(Cl)cc1CNC(=O)C1CCCO1 +N#CCOc1cccc(CC(=O)Nc2cn[nH]c2)c1 +CN(Cc1ccccc1)C(=O)COc1ccccc1 +CS(=O)(=O)NCCC1CCCCN1c1nc2ccccc2o1 +O=C(Nc1ccc(-n2cccn2)cc1)c1cc(N2CCOCC2)ccn1 +O=C(CCNC(=O)c1ccco1)Nc1ccccc1 +Cc1cccc(NS(=O)(=O)c2cc(C)c3[nH]c(=O)cc(C)c3c2)c1 +CCCn1c(=O)cc(N2CCC(C)CC2)[nH]c1=O +CCOc1ccccc1C(=O)NC(C)C(=O)N1CCCCC1 +Cc1cc(C)n2nc(SCCN3CCOC3=O)nc2n1 +N#Cc1cccc(Cn2nc(-c3ccc(F)cc3)oc2=O)c1 +CNc1nc(-c2cc3c(n(C(C)C)c2=O)CCC3)cs1 +Nc1cc(Cl)c(OCCOCC(F)(F)F)c(Cl)c1 +CCOC(=O)c1ccccc1NC(=O)Cc1nonc1N +O=C(NCc1ccc(Cl)cc1Cl)c1cnn2c1OCCC2 +Cc1noc(CCC(=O)NCCc2cccc(F)c2)n1 +Cc1nc(C)c(C2NCCc3cc(F)c(Cl)cc32)s1 +CCC(=O)Nc1ccc(N2CCN(c3ccccc3)C2=O)nc1 +NC(=O)c1cc(-c2csc(Nc3ncnc4ccccc34)n2)c[nH]1 +Cc1csc(NC(=O)c2cc(-c3ccccc3Cl)nn2C)n1 +CCc1ncc2c(n1)CN(C(=O)c1ccc(-n3cnnc3)cc1)C2 +CC(=O)Nc1cccc(NC(=O)NC2CCc3ccccc32)c1C +COCCNC(=O)N1CCC(NC(=O)Nc2ccc(F)cc2)CC1 +CC(=O)c1ccc(-n2nnc(-c3cccnc3)c2N)cc1 +Cc1cccc(C(N)=O)c1NCC(=O)N(C)CC(=O)NC(C)(C)C +CCOC(=O)c1c(NC(=O)C2CC2)sc(C)c1CC +c1cc(-c2nc(C3CCOC3)no2)cc(N2CCOCC2)c1 +CCOC(=O)c1cnn(-c2ccc(Cl)cn2)c1N +Cc1cc(C)n(NC(=O)Cn2cc(Cl)c(C)n2)c(=O)c1 +CCCn1c(=O)[nH]c(=O)c2cc(C(=O)Nc3ncc(C)s3)cnc21 +CCNC(=O)c1cc(S(=O)(=O)Nc2c(C)cccc2C)ccc1C +CCN(CC)S(=O)(=O)c1cc(NC(=O)c2cccn2C)ccc1C +CCC(COC)NC(=O)N1CCN(c2ccc(Cl)cn2)CC1 +COCCC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +O=C(CCNC(=O)c1ccsc1)Nc1ccc2c(c1)OCCCO2 +CCNC(=O)N1CCC(NC(=O)NCCCc2cccc(F)c2)C1 +COc1ccc(CNc2ccc(CO)cc2)cc1C +CCC(C)NS(=O)(=O)Cc1cccc(NC(=O)N(C)C(C)C)c1 +CCOc1ccc(NC(=O)NC2CCCC2C(=O)OC)cc1 +CCc1nnc(CNc2ccc(C)cc2OCC(=O)N(C)C)o1 +Cc1ccc(OCC(=O)N2CCNC(=O)CC2)cc1C +CCN(CC=Cc1ccccc1)C(=O)c1c(C)[nH]c(C(C)=O)c1C +CCOCC1CN(C(=O)c2ccoc2)Cc2cnn(C)c21 +CC(NC(=O)CCc1ccco1)c1nc2ccccc2o1 +CCc1noc(CC)c1CNC(=O)c1ccc(Cn2cccn2)cc1 +CN(C)C(C(=O)N1CCCC1Cn1cccn1)c1ccccc1 +CCOC(=O)c1cnc2ncnn2c1-c1ccccc1 +CCc1n[nH]c(SCC(=O)N2C3CCC2CC(O)C3)n1 +CCCNC(=O)NC(C)c1cc2c(cc1Br)OCCO2 +CCCCS(=O)(=O)NCC(=O)NC1CCOC2(CCCC2)C1 +Cc1ccc(CNC(=O)NCC(O)c2ccco2)cc1F +CCOc1cc(NC(=O)Cc2c[nH]c3ccccc23)ccc1OC +CCS(=O)(=O)N1CCN(Cc2cnc(C)n2-c2ccccc2)CC1 +Cc1ccccc1CNc1ncnc2sccc12 +CCCCCNC(=O)CCn1[nH]c(=O)c2ccccc2c1=O +Cc1nc2c(O)cccn2c(=O)c1Cc1ccccc1 +COc1ccc(CN2C(=O)C(C)CS2(=O)=O)cc1 +C=CCNC(=O)c1nc(C(=O)N2CCc3sccc3C2C)cs1 +Cc1ccc(C)c(S(=O)(=O)N(C)c2ccc(O)cc2)c1 +CC(C)CCN1C(=O)CCc2cc(NS(C)(=O)=O)ccc21 +CCCCN(C)C(=O)CN1C(=O)CCSc2ccccc21 +CC(=O)N1CCCC1c1cncc(Nc2cccc(C)n2)n1 +CCOC(=O)c1cc(F)c(Cl)c(S(N)(=O)=O)c1Cl +CC(C)COc1cccc(CNC(=O)c2ccc(C(N)=O)cc2)c1 +Cc1nn(C)c(C)c1C(C)NC(=O)c1ccccc1Cn1cncn1 +O=C(Nc1ccc2c(c1)CN(C(=O)C1CC1)CC2)C1CC1 +CCCn1cc(NC(=O)c2cccc(C)c2)ccc1=O +Cc1ccc(NCC(=O)Nc2ccccc2N2CCCC2=O)cc1C +CC1CCN(C)c2ccccc2N1C(=O)c1scnc1C1CC1 +[H]N=c1n(CC)c2ccccc2n1CC(O)COc1ccccc1 +CCCCOc1ccc(C(=O)Nc2nc(C)no2)cc1 +COC(=O)c1cc(CNC(=O)Cc2c(C)noc2C)ccc1OC +CCCCNS(=O)(=O)c1ccc(OC)c(OC)c1 +CCOCC1CCN(C(=O)CCc2cc(Cl)cs2)CC1 +COc1cccc(C(=O)N(Cc2ccc(C)cc2)Cc2ccco2)c1 +O=C1NCCC1NCc1ccccc1-c1ccc(Cn2cccn2)cc1 +CSc1nc(-c2ccco2)nc(C)c1C(=O)N1CCOC(C)(C)C1 +CC(C)N(C(=O)c1scnc1C1CCCC1)C1CCOCC1 +O=C(Cc1nc2ccccc2oc1=O)c1ccccc1 +CCc1onc(C)c1NC(=O)NCc1nc2ccccc2s1 +CC(=O)N1CCCC1c1nnn2cc(Nc3cccc(F)c3)ccc12 +CN1CCN(C(=O)CCC(=O)NCc2ccc(F)cc2)CC1 +COCC(C)NC(=O)CS(=O)(=O)c1ccc(OC)cc1 +Cc1ccc(OC(=O)Cc2csc(C)n2)c(C)c1 +Cc1nc(Cn2cccc2C(=O)Nc2ccc(C)c(C)c2)no1 +O=C(Nc1ccnn1CC1CC1)NC(CO)c1ccccc1 +COCC(=O)Nc1cccc(-c2nc(-c3ccc(OC)cc3)no2)c1 +Cc1ccc(NS(=O)(=O)c2ccc(-c3ccc(=O)[nH]n3)s2)cc1 +CC(Sc1nnc(C2CC2)n1Cc1ccco1)C(=O)NC1CC1 +O=C(CCNC(=O)c1ccsc1)NCC(O)C1CC1 +Cc1cc(-c2nncn2C2CCCCC2)ccc1N +COC(=O)c1c(C)[nH]c(C(=O)Nc2cccc(-n3cccn3)c2)c1C +Cc1nc(C(C)NC(=O)N2CCc3c(F)ccc(F)c3C2)cs1 +Cc1ccc(NC(=O)C2CCN(S(=O)(=O)N(C)C)CC2)c(C)c1 +O=C(Nc1cccc(OCC2CCCO2)c1)c1cccc2ncccc12 +O=C(Cc1ccc(F)cc1Cl)NCc1csc(=O)[nH]1 +CC(=O)Nc1ccccc1NC(=O)c1ccc2ccccc2c1 +CC(NC(=O)CCc1ncc(-c2ccccc2)o1)c1ccccn1 +CCOC(=O)C1CCCCN1S(=O)(=O)c1ccc(F)cc1F +COC(=O)CCN(C)C(=O)CCc1ccccc1Cl +CC(=O)N1CCc2cc(NCc3c[nH]nc3C(C)(C)C)ccc21 +CSc1ccc(CNC(=O)C(C)Sc2nncs2)cc1 +O=C(CCS(=O)(=O)c1ccc(Cl)cc1)OCC1CC=CCC1 +CC(C)(C)OC(=O)Nc1ccoc1S(N)(=O)=O +O=C(c1cccc2ncccc12)N1CCCC(n2cccn2)C1 +CC1C(=O)OC(c2ccccc2)N1C(=O)c1ccccc1 +COc1cc(OC)cc(C(=O)N(Cc2cccs2)C2CC2)c1 +CCC1CCC(NC(=O)N2CC(C)OC(C)C2)CC1 +CC(CNC(=O)Cn1ncc2ccccc2c1=O)N1CCOCC1 +CCS(=O)(=O)c1cccc(C(=O)Nc2sc(C)c(C)c2C#N)c1 +COc1cc(OC)cc(C(=O)Nc2cnc(N(C)C)nc2)c1 +Cc1cc(-c2ccc(S(C)(=O)=O)cc2)nc2ccccc12 +O=C(NCCCNc1ncccn1)C1COCCO1 +COc1cc(CO)ccc1OCC(=O)NCC(C)C +CC(C)S(=O)(=O)NCc1ccccc1Cn1cccn1 +Cc1nc2ncnn2c(C)c1CCC(=O)Nc1ccc2c(c1)CCC2 +COc1cc(S(=O)(=O)N2CCN(C(C)=O)CC2)ccc1Cl +Cc1ccc(OC(C)C(=O)NC(C)C)c(Br)c1 +CSc1ncc(C(=O)Nc2ccncc2)c(-c2ccccc2)n1 +Cn1cc(C(=O)N2CCc3ccccc32)c(C(C)(C)C)n1 +Cc1ccc(Cl)cc1S(=O)(=O)N1CCCC1c1ncc[nH]1 +COC(=O)Cn1cc(NC(=O)c2ccc(C)nc2)cn1 +NC(=O)COc1cccc(C(=O)N2CCC3(CCCO3)CC2)c1 +O=C(NCC(=O)N1CCCC1)NCC(=O)N1CCCc2ccccc21 +COc1ccc(OC)c(NC(=O)c2ccccn2)c1 +CCOc1cc(F)ccc1NC(=O)NCc1ccc(OC)cc1OC +CC(C)NC(=O)COC(=O)c1cnn(-c2ccccc2)n1 +O=C(OCCc1cccnc1)c1ccc(S(=O)(=O)C(F)F)cc1 +O=C(CSc1ncn[nH]1)N(c1ccccc1)c1ccccc1 +CC(Cc1ccc(Cl)cc1)N(C)C(=O)C1CC1c1cnn(C)c1 +CN(c1ccccc1C(N)=O)S(=O)(=O)c1cccc(Cl)c1 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)C1(O)CCCC1 +COc1ccc(S(=O)(=O)NC(C)CC(C)C)c(N)c1 +Cc1ccc(NC(=O)Nc2ccc(C(N)=O)cc2)cc1C +CC(C)c1nc2ccccc2n1C1CCCCC1O +CC(=O)Nc1nonc1-c1nc2ccccc2n1CC1CC1 +O=C(NC1(c2cccc(Cl)c2)CC1)C1CC2CCC1O2 +O=C(c1ccccc1O)N1CCN(Cc2cc[nH]n2)CC1 +COC(=O)C1(CNc2nccnc2C#N)CCCC1 +Cc1nnc(N2CCN(C(=O)CC3C=CCC3)CC2)c(C(N)=O)c1C +Cc1noc2ncnc(Nc3cccc(C(F)(F)F)c3)c12 +N#Cc1cccc(CNC(=O)N2CCOC(c3ccccc3F)C2)c1 +COc1ccc(NC(=O)C(Sc2ncn[nH]2)c2ccccc2)cc1 +C=CCN(CC=C)C(=O)CSc1ccccc1F +CC1CN(C(=O)c2cccs2)C(Cc2ccccc2)CN1 +COC(=O)c1ccc(NC(=O)c2cc(C)nc3onc(C)c23)cc1 +O=c1c2cnc3nc(C(F)(F)F)nn3c2ccn1-n1cnnc1 +CN(CCn1ccc2ccccc21)C(=O)C1Cc2ccccc2CN1C +CNc1cc(-c2ccc3c(c2)CCC(=O)N3C)nc(C)n1 +N#Cc1cccc(S(=O)(=O)N(Cc2ccc(F)cc2)C2CC2)c1 +CCCS(=O)(=O)NC1CC(C)(C)Cc2oc(C)cc21 +COCCCN(C)C(=O)Nc1cccc(Cl)c1 +CC(=O)c1cccc(OC(C)C(=O)Nc2ccc(C#N)c(Cl)c2)c1 +Cc1nc(NC(=O)c2ccc3[nH]cnc3c2)sc1C +Cc1n[nH]c(C)c1CCOC(=O)c1ccc(Br)cc1 +CCN(CC)S(=O)(=O)c1ccc(OC)c(C(=O)N2CCCC2)c1 +Cc1noc(C)c1CN(C)C(=O)NC(C)c1cc2ccccc2o1 +O=C1CC(C(=O)Nc2cccc(-n3ccnc3)c2)c2ccccc2N1 +COc1ccccc1NC(=O)CSc1nc2ccccc2cc1C#N +CC1CCN(C(=O)NCc2ccnc(OC(C)(C)C)c2)C1C +COc1cc(OC)c(NC(=O)N(C)CCC(C)O)cc1F +O=C(CO)N1CCN(C(=O)c2ccn(-c3cccc(Cl)c3)n2)CC1 +NC(=O)CC1CCN(C(=O)c2csc(-c3ccsc3)n2)CC1 +O=C(COc1ccccc1F)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(C)(C)C(=O)NCCC(=O)NCC(=O)N1CCCc2ccccc21 +CC(=O)N1CCc2ccccc2C1CC(=O)N1CCOCC1 +CC(C)c1ccc(-n2ccnc2SCc2n[nH]c(=O)[nH]2)cc1 +COc1c(Cl)cc(Cl)cc1-c1nc(C)cc(N)n1 +C#CCNC(=O)c1ccc(OCc2cn3ccccc3n2)cc1 +CC1CN(C(=O)Nc2cccc(Br)c2)CCO1 +COC(=O)C(C)(C)NC(=O)C1CC(=O)N(c2cccc(C)c2C)C1 +COc1ccc(S(=O)(=O)NCCc2ccccn2)cc1C(N)=O +CCN(Cc1cccs1)S(=O)(=O)c1cccc(F)c1 +CNC(=O)NCC(=O)Nc1cccc(CCC(F)(F)F)c1 +O=C1N(CC2CCCC2)CCC12CCN(c1ncc(F)cn1)CC2 +O=C(CCC=Cc1ccccc1)N1CCN(c2ncccn2)CC1 +CCNC(=O)c1cc(S(=O)(=O)N(C)C)ccc1OC +C=C(C)C1NCCc2cc(OC)c(OC)c(OC)c21 +Cc1ccc(C)c(OCc2ncc(CC#N)s2)c1 +Cn1c(-c2cccc(Br)c2)cn2c3ccc(N)cc3nc12 +COC(=O)CNC(=O)C(N)c1ccc(C)c(C)c1 +COc1ccc(-c2cc3ncc(C(C)=O)c(C)n3n2)cc1 +COCC(=O)N1CCC(C(=O)NCCc2nc(C)cs2)CC1 +Cn1cnnc1C1CCCN(C(=O)C(C)(C)C)C1 +Cc1cccc(S(=O)(=O)Nc2c[nH]nc2C)c1Cl +COC(=O)CN(C(=O)c1cc(C)nc2c1cnn2C(C)C)C(C)C +COC(=O)c1ccc(OCc2cc(=O)n3ccccc3n2)c(OC)c1 +CCN(CC)S(=O)(=O)c1cc(NC(=O)NC)ccc1Cl +COc1cccc2c(C)c(C(=O)NCC(=O)NC(C)(C)C)oc12 +CCCOCC(=O)N1CCC(c2nnc3ccccn23)CC1 +CN(C(=O)COc1ccccc1N)c1ccccc1 +CC(C)NC(=O)c1nnn(-c2cccc(Cl)c2)c1N +Brc1ccc(NCc2cncnc2)cc1 +O=C(COC(=O)C1CC1)Nc1cccc2ccccc12 +COCCOC(=O)C1CCN(c2ncccn2)CC1 +O=C(NCc1ccc2nonc2c1)C1COc2ccccc2C1 +COc1cc(C(=O)Nc2nnc3n2CCS3)cc(OC)c1OC +CNC(=O)C(NC(=O)Nc1cccc(OC)c1)c1ccc(F)c(F)c1 +CC(C)(C)c1nnc(SCc2nccn2Cc2ccccc2)n1N +CCn1c(SCC(=O)N2CCN(CCO)CC2)nc2ccccc21 +CNC(=O)c1cccc(NCC(=O)Nc2c(C)cc(C)cc2C)c1C +CCc1ccc(OC)c(-c2cc(C(=O)OC)nc(=O)[nH]2)c1 +CCC(C)(CC)NC(=O)c1cncc(Br)c1 +CNc1ccc(C)cc1C(=O)NCCc1ccsc1 +N#Cc1ccc(CN2CCN(C(=O)c3cc(Cl)ccc3F)CC2)o1 +Cn1cc(C(N)=O)cc1C(=O)OCc1cc2ccccc2[nH]c1=O +CCCC(C)(NC(=O)c1cc(C)n[nH]1)C(=O)OC +COc1ccc(CCC(=O)Nc2ccnc(C)c2)cc1OC +COc1ccc2nc(SCc3nc(C)no3)[nH]c2c1 +O=C(Nc1nc2c(s1)CN(C(=O)C1CCCC1)CC2)C1CC1 +Cc1ccsc1-c1cccc(NC(=O)NCCc2nc[nH]n2)c1 +COCCCCC(=O)NC(C)c1ccc(F)cc1Cl +COc1ccc(-c2ccc(C#N)c(=O)n2CC(O)CO)cc1 +Cc1ccc(CN(C)C(=O)Cc2ccc3c(c2)OCCO3)o1 +Cc1cc(C)n(C(C)CC(=O)Nc2ccc(F)c(Cl)c2)n1 +Cc1cccnc1CNC(=O)c1cccc(-c2ccc(O)cc2)c1 +CCC(NCCc1ccncc1)c1ccc(O)cc1 +Cc1ccc(-n2nnc(C(=O)Nc3ccccc3C)c2C)cc1 +CC(C)(C)c1cc(C(N)C(F)(F)F)cc(C(C)(C)C)c1O +CC(=O)Nc1nc2ccc(CC(=O)NC(C)(C)C)cc2s1 +CCC(C)NC(=O)C(C)NC(=O)C(C)NC(=O)Nc1ccccc1 +Cc1ccn2cc(C(=O)NCC(O)c3cccc(Cl)c3)nc2c1 +O=C(CC(F)(F)F)N1CCN(C(=O)C2(c3ccccc3)CC2)CC1 +CCc1ccccc1NC(=O)c1c[nH]c2cc(Cl)ccc2c1=O +Cc1cc(-c2cccc(OC(C)C(N)=O)c2)nc(C(C)C)n1 +COc1ccccc1C(=O)N(Cc1cnc2ccccn12)C1CC1 +O=C1c2ccccc2CS(=O)(=O)N1Cc1cn2ccccc2n1 +C=CCOc1ccc(CN2CCOCC2C2CC2)cc1 +O=C(NCc1ccccn1)C1(c2cc(-c3ccccc3)on2)CC1 +CC(C(=O)N1CCCC1)N1CCN(C(=O)NC2CCCCC2)CC1 +COc1ccccc1-c1cc(CN(C)C(=O)c2cccs2)no1 +C=CCc1ccccc1OCC#CCNC(=O)c1ccncc1 +CCC(=O)c1ccc(SCC(=O)N2CCCCC2)cc1 +COC(=O)CCC(=O)N(C)C(C)C(O)c1ccccc1 +COC(=O)c1nccc2c(N)cc(Br)cc12 +O=C(c1cccc(F)c1)N1CCN(c2nccs2)CC1 +Cc1ccc(-n2c(SC(C)C(N)=O)nc3ccccc3c2=O)nc1 +O=c1cc(CSc2nnc(C3CCCC3)[nH]2)nc2sccn12 +COC(=O)CC(C)C(=O)c1ccc2c(c1)OCCCO2 +O=C(CCc1ccccc1)N1CCN(C(=O)c2ccc[nH]2)CC1 +CCCCN(C)S(=O)(=O)N1CCC(C(=O)N(C)C)CC1 +Cc1nn(C)c(C)c1C(=O)Nc1ccc2c(c1)OC(C)(C)O2 +Nc1ccc(C(=O)OCC(=O)c2cccs2)cc1 +CCc1cc(NCc2ccncc2)n2nc3nc(C)cc(C)c3c2n1 +CCOc1cc(Cl)ccc1NC(=O)Cc1cc(C)[nH]n1 +CC(=O)c1c(C)[nH]c(C(=O)N(CCC#N)CC2CC2)c1C +COc1ccc(CNC(=O)NC(C)c2ccc(C)o2)cc1F +CN(C)c1ccc(Cl)cc1NC(=O)NCCc1ccccn1 +CCc1noc(C(C)NC(=O)Cc2ccncc2)n1 +Cn1nccc1C(=O)OCC(=O)NCc1ccccc1 +CC(C)(CNC(=O)NCCCN1CCOCC1)c1ccncc1 +c1cc(-c2ccn(CC3COCCO3)n2)cc(-c2nccs2)c1 +COc1ccc(CNC(=O)NCC(C)(C)C(N)=O)cc1 +O=C(Nc1ccc(F)cc1Cl)c1cccc(OCC(F)F)n1 +CCOc1cc(CNC(=O)c2cc(C)sc2C)ccc1OC +CCN1CCOC(CNCc2ccc(OC)c(F)c2)C1 +O=S(=O)(c1ccc(OC(F)(F)F)cc1)N1CCC(O)CC1 +CCCCc1ccc(S(=O)(=O)N2CCCC(=O)C2)cc1 +O=S(=O)(NCC1CCCO1)c1ccccc1Cl +Cc1nccc(CNC2C(=O)Nc3cccc(Br)c32)n1 +CCn1cc(C(=O)Nc2cc(C)ccn2)c(=O)c2cc(Cl)ccc21 +C=CCn1cc(C(=O)OCC)c(=O)c2ccc(F)cc21 +COC(=O)c1cc(CSc2nc(C)nc3ccccc23)oc1C +O=C(NCC(NC(=O)c1ccccc1)C1CC1)c1ccccc1 +CC(C)CCCC(C)NC(=O)NC1CCC2(CC1)OCCO2 +CC(C)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)NCCO +Cc1nc(-c2cc(Br)cs2)nc(N)c1C +CCOc1ccccc1NC(=O)Cn1c(C)ccc(C#N)c1=O +Cc1cc(N)nc(SCc2cn3ccccc3c2C#N)n1 +COc1ccccc1-c1c2c(=O)[nH]ccc2nc2nc(C)nn12 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)NCC(C)O +Fc1ccc(CSc2nc3ncccn3n2)cc1Br +COCc1cccc(C(=O)N(C)C2(C(=O)OC)CCCCC2)c1 +O=C(CCCNC(=O)c1ccnc2ncccc12)Nc1ccccc1 +COC(=O)c1ccc2c(c1)nc(C(C)O)n2C(C)C +COc1ccc(-c2nnn(Cc3c(F)cccc3Cl)n2)cc1OC +CC(=O)N1CCCCC12CCCN(C(=O)c1ccno1)C2 +CCSc1ccccc1C(=O)Nc1cnn(C2CCOC2)c1 +COC(=O)CCC(=O)Nc1ccc2c(c1)oc(=O)n2C +CC(CNC(=O)N1CCNC(=O)C1)Oc1ccccc1 +O=c1[nH]c(C=Cc2ccc3c(c2)OCCO3)nc2ccccc12 +O=C(c1cncs1)N1CCCC(c2nc3ccccc3[nH]2)C1 +CC(C)OC(C)C(=O)N1CCc2c([nH]n(CCO)c2=O)C1 +COC(=O)CCc1cc(C)ccc1S(=O)(=O)CC(C)C +CC(=O)c1cccc(S(=O)(=O)N2CCOC3CCCCC32)c1 +Cc1cccnc1NC(=O)c1ccc(Cl)cc1-n1cnnn1 +Cc1cc(-c2noc(-c3cccnc3)n2)c2ccccc2n1 +Cc1cc(C)n(C(=O)COc2ccc(Br)cc2)n1 +Cc1cc(NCc2ccc(F)cc2F)ccc1C(N)=O +CC(=O)c1csc(NC(=O)Cc2ccc3c(c2)OCCO3)n1 +O=C1OC(C(=O)NCCc2ccccc2)Cc2ccc(Cl)cc21 +Cc1ccc(F)c2c1CCCN2C(=O)c1nc2nccc(C)n2n1 +Cn1ccnc1-c1ccccc1C(=O)N1CCNC(=O)C1 +COC(=O)CC(c1ccc(OC)c(Br)c1)C1CC1 +Cc1cc(C(=O)Nc2nc3ccc4ccccc4c3s2)no1 +Nc1nonc1-c1noc(Cn2nnc3ccccc32)n1 +Cc1noc(C)c1S(=O)(=O)NCCCn1c(C)nc2ccccc21 +CSc1nc2ccccc2c(=O)n1CC1CCCO1 +Cc1cccc2c1NC(c1ccc(Cl)c(F)c1)NC2=O +CNC(=O)COC(=O)C1COc2ccc(F)cc2C1 +Cc1cc(Br)ccc1C(=O)N1CCCCC1CCO +COCc1ccc(C(=O)N2CCN(C(=O)CCC(C)C)CC2)cc1 +CCC1(CC)CNc2cc(S(N)(=O)=O)ccc2O1 +CC(Cn1cncn1)NC(=O)c1cc(Br)cn1C(C)C +COc1ccc(-c2nc3cc(C)ccn3c2CC#N)cc1OC +COc1ccc(C(=O)Nc2ccc(C#N)cc2)c(OC)c1 +CCOc1cc(NC(C)=O)c(Cl)cc1C(=O)OC +CC(C)(C)C(=O)N1CCCC(C(=O)NC2CC2)C1 +CCC(CC)NC(=O)NCc1ccc(C)cc1N(C)C +O=C1CN(C(=O)COc2ccc3c(c2)CCC3)c2ccccc2N1 +N#Cc1ccc(C(=O)NCCCNc2ncccn2)cc1 +O=C(c1ccc(Br)cc1)N(CCO)CC(F)(F)F +COCCC(C)NC(=O)N1CCc2cc(F)ccc2C1 +O=C(NCC1(c2ccccc2)CC1)c1cnccn1 +Nc1nc2c(cc1C(=O)Nc1ccc(Cl)cn1)CCC2 +Cc1cc(C)c2c(N3CCC(n4nc(C)cc4C)C3)ncnc2n1 +CCN(CC)C(=O)CSc1ncnc2sc(C)c(C)c12 +CCOC(CC)C(=O)N1CCN(S(C)(=O)=O)CC1 +CC(NC(=O)c1ccccc1S(C)(=O)=O)C(=O)N(C)C +CCN(Cc1ccncc1)C(=O)c1cc2c(s1)SCC2 +CCCC(=O)Nc1ccccc1Cc1nc(-c2cccnc2)no1 +Cc1ccc(S(=O)(=O)CC(=O)NCC2CCCCC2)c(C)c1 +CC(C)CCn1cnc2c(cnn2-c2ccc(Cl)cc2)c1=O +CCCNC(=O)CNS(=O)(=O)c1c(Cl)cccc1Cl +O=C(COc1ccc(F)c(Cl)c1)NCc1ccc(F)cc1 +COc1ccc(-c2ccc(OC)c3nc(N)nn23)c(OC)c1OC +Cn1c(=O)c2c(nc(S(=O)(=O)Cc3ccccc3)n2C)n(C)c1=O +Cn1nccc1CNC(=O)c1csc(-c2ncccn2)n1 +COc1ccccc1N1CCN(C(=O)C2CN(C(C)=O)C2)CC1 +CC(NC(=O)CCN1CCCCCC1=O)c1ccc(O)c(F)c1 +CCC(=O)Nc1ccc(S(=O)(=O)Nc2cc(C)ccc2O)cc1 +CCN(Cc1ccccc1Cl)C(=O)c1cc(C(N)=O)cs1 +O=S(=O)(Cc1ccc(Cl)cc1)c1ccccn1 +Cc1nc(CNc2ccc(F)c(F)c2F)cs1 +CCN1CC(C(=O)NCc2cccc(CN3CCCC3=O)c2)CC1=O +O=C(c1ccnnc1)N1CCC(O)C1Cc1ccccc1 +Cc1noc(C2CN(Cc3cccc(C#N)c3)Cc3ccnn3C2)n1 +c1cn(-c2ccc(CNCc3cnc(N4CCCC4)nc3)cn2)cn1 +CCN1CCN(C(=O)c2c(C)nc(C(C)(C)C)[nH]c2=O)CC1 +CCc1c(C)sc2nc(C(C)C)n3c(=O)[nH]nc3c12 +Cc1nc2ccc(F)cc2c(=O)n1CC(=O)NCc1ccccn1 +CC(C)N(CC1CC1)c1ccc(N)cc1C(F)(F)F +CC1CCN(C(=O)CCc2ccco2)c2ccccc2S1 +COc1ccc(NC(=O)C2(C)Sc3ccccc3N(C)C2=O)cc1 +CCOc1cc(NCC2CCCO2)nc(C(C)(C)C)n1 +COc1cccc(CN(C)C(=O)CNc2ccc(C)cc2F)c1 +CC(C)NC(=O)C1CN(Cc2cnn(C)c2)CC2OCCC21 +COC(=O)NCCOC(=O)c1c(-c2ccccc2)noc1C +O=C(NCc1ccccn1)Nc1cccc2ccccc12 +Cc1ccc(OCC(=O)NCC(C)(C)N2CCOCC2)c(C)c1 +CC(NC(=O)c1cn2ccccc2n1)C1CCCO1 +CN(CCNC(=O)Nc1cnn(C)c1)c1ccccc1 +CCc1noc(CNc2cc(C(=O)N3CCOCC3)ccc2C)n1 +Nc1ccccc1-c1csc(-c2cc[nH]c(=O)c2)n1 +O=C1CCc2cc(NC(=O)C3CC(=O)Nc4ccccc43)ccc2N1 +COc1ccc(F)cc1NC(=O)Cc1ccc(-n2cccn2)cc1 +Cc1cc(Br)c(O)c(C(=O)N(C)CC2CCCO2)c1 +O=C(NCCc1c[nH]c2ccccc12)NCc1ccc(F)cc1 +O=C(CCCc1nc(-c2cccs2)no1)Nc1nccs1 +C#CCN1C(=O)C(CC)Nc2cc(F)c(F)cc21 +Cc1cc(C)nc(NCC(=O)N2CCC(Cc3ccccc3)CC2)n1 +CC(Oc1ccccc1)C(=O)Nc1cnc2c(cnn2C(C)C)c1 +CC(C)C(NC(=O)c1ccco1)C(=O)Nc1nc2ccc(F)cn2n1 +O=C(NC1(c2ccc(F)cc2F)CCOCC1)C1CCC1 +COC(=O)c1ccc(S(=O)(=O)NCc2cc(C3CC3)n(C)n2)cc1 +Cc1cc(C)n(Cc2ccc(F)c(Br)c2)c(=O)n1 +O=C(c1cc2ccccc2oc1=O)N1CCC(Cn2cccn2)CC1 +CCc1cccc(C)c1NC(=O)c1cc(C)oc1C +Cc1ccc(S(=O)(=O)NCCc2cc(C)no2)c(C)c1 +O=C1CC(NC(=O)c2cc(-c3ccc(F)cc3)n[nH]2)CN1 +Cc1ccc(C)c(SCC(=O)NCCn2cnnc2C2CC2)c1 +Cc1nn(C)c(C)c1CCC(=O)N1CCCC1c1nccs1 +COc1cc(C)c(C)cc1S(=O)(=O)NCc1ccccn1 +O=C(Cn1cc(C(=O)C2CC2)c2ccccc21)NCc1ccccc1 +Cc1nn(C)c2nc(C(C)C)cc(C(=O)N3CCCC3)c12 +O=C(NC1CN(c2ncccn2)CC2CCCOC21)c1cccnc1 +CCN(CC)C(=O)C(C)Oc1cccc(Cl)c1 +COc1ccc(NC(=O)C2CC2)cc1S(=O)(=O)N1CCOCC1 +COCC1CN(C(=O)Nc2cccnc2)CCO1 +COCCCCCn1cnc2sc(C)cc2c1=O +COc1ccc(CCC(=O)NCC(C)C)cc1N +COc1ccc(CN(C)S(=O)(=O)c2ccc(OC)c(C)c2)cc1 +Cc1ccc2cccc(C(=O)NCCCNc3cccc(F)c3)c2n1 +CS(=O)(=O)NCCNC(=O)NCc1ccc2c(c1)OCO2 +CS(=O)(=O)c1cc(C(=O)Nc2ccccc2Cl)ccc1Cl +Cc1ccsc1C(=O)N1CCOc2ccncc21 +COCC(=O)N1CCN(c2cc(C)ccc2C)C(=O)C1C +CC(C)Oc1ccc(C2CC3(C)NC(=O)C2C(=O)N3)cc1 +CC(=O)NCc1ccc(C(=O)N2CCCCC2C(N)=O)cc1 +CCc1cccc(C)c1NC(=O)C(C)Sc1nnc(CC)n1N +CCC1C(=O)NCCN1C(=O)Nc1cccc(Br)c1C +CCCN(Cc1cc(C)no1)S(=O)(=O)N1CCCCC1 +COc1ccc2ccn(CC(=O)NCCC3=CCCCC3)c(=O)c2c1 +CC(NC(=O)c1ccccn1)c1nc(C(C)(C)C)cs1 +Cc1ccnc(NC(=O)c2nnn(-c3ccccc3)n2)c1 +COc1ccc2c(c1)CCNC2c1cc(F)cc(C#N)c1 +CS(=O)(=O)N1CCC(Oc2ccc(C(F)(F)F)cn2)CC1 +COc1cc(C(=O)Nc2cccc(OC(C)=O)c2)cc(OC)c1OC +Cc1ccsc1C(O)CNC(=O)C1COc2ccccc2O1 +CC(=O)c1sc(C(N)c2c(C)cccc2C)nc1C +CCc1nc2nnc(-c3ccnc(CCOC)n3)c(C)n2n1 +Cc1cc(-c2cnc(N3CCC(O)CC3)nc2-c2ccoc2)on1 +COc1cc2[nH]c3c(SCC(N)=O)ncnc3c2cc1OC +Cc1ncc(CN(C)C(=O)c2cc3ccccc3c(=O)[nH]2)s1 +Cc1cc(C)cc(C(=O)NC(C)c2ccc(S(C)(=O)=O)cc2)c1 +CCCc1cc(C(=O)NCCc2nc(-c3ccccn3)no2)[nH]n1 +N#Cc1ncn(Cc2cccc(OCc3ccccc3)c2)n1 +CCCCN(C(C)CC)S(=O)(=O)c1ccc(O)cc1 +CNC(=O)C1CCC2C(CCN2Cc2nccs2)O1 +Cc1cccc(C(=O)NCC2COCc3c(C)nnn3C2)n1 +Cc1cc(N2CCC(C(=O)Nc3ccccc3)C2=O)ccc1F +O=C(NCc1ccccc1)c1cncc(-c2cc(F)ccc2F)c1 +COc1ccc(NC(=O)NC(C)Cc2cnccn2)c(OC)n1 +CCN(CC)C(=O)C1CCN(C(=O)c2ccc(C)cc2C)CC1 +Cc1noc(NC(=O)CSc2cccc3cccc(Cl)c23)n1 +Cc1ccc2nc(NC(=O)c3ccc(-n4ccnc4)cc3)sc2c1 +COc1ccc(-n2ccn(Cc3ccc(Cl)cc3)c(=O)c2=O)cc1 +C=CCNC(=O)C1CCN(c2cc(OC)cc(OC)c2)C1=O +CC(NC(=O)NCCCn1cccn1)c1ccc2c(c1)NC(=O)CO2 +CCN(Cc1ccccc1)C(=O)CSc1nc(C)cc(C)c1C#N +COC(=O)CCC(=O)c1ccc(S(=O)(=O)C(C)C)cc1 +Cc1oc(-c2ccsc2)nc1CC(=O)NC1CCCCCC1CO +O=C(NCc1cccc(C(F)(F)F)c1)c1n[nH]c(=O)[nH]1 +CN(C)C(=O)c1ccc(NC(=O)C(C)(C)C)cc1Cl +O=C(c1cnc2ccsc2c1)N1CCc2ccccc2C1 +CCCCN(C)C(=O)NCCc1cnn(-c2ccccc2)c1 +CCC(C)C1NC(=O)N(Cc2ccc(S(N)(=O)=O)cc2)C1=O +COC(=O)c1c(C(=O)OC)c(-c2ccc(C)cc2)n2c1CCC2 +CCN(CC(C)C)C(=O)CN(C)C1=NS(=O)(=O)c2ccccc21 +CS(=O)(=O)N1CCC(C(=O)Nc2nc3c(s2)COCC3)CC1 +Cc1ccc2cccc(C(=O)NCCc3ccsc3)c2n1 +Cc1cc(C(=O)Nc2nc(-c3cccc(O)c3)cs2)c(C)o1 +COC(=O)CNC(=O)c1ccc(NC(=O)c2ccccc2Cl)cc1 +O=C1CCCc2[nH]c(=O)c(C(=O)Nc3cccc4ccccc34)cc21 +O=C(CCNC(=O)c1cccs1)OCC1CCCCO1 +CCOc1ccccc1NC(=O)N1CCC(C(=O)N(C)C(C)C)CC1 +CC(C)(C)CC(=O)NCC(=O)NCCc1ccccc1 +Cc1ccc(-c2cc(CNC(=O)Cn3cnc4ccccc43)no2)cc1 +CCOC(C)C(=O)NC(c1ccc(OC)cc1)C1CCOCC1 +Oc1ccc2c(c1)C(COCc1ccccc1)NCC2 +O=C(c1cccc2ccccc12)N(CC1=CC2N=CC=C2C=C1)C1CC1 +COc1cccc(C(O)c2ccc3c(c2)OCCO3)c1 +COc1cc(NC(=O)CN(CCc2ccccc2)C(C)=O)ncn1 +CCn1cc(NCc2cc(Br)ccc2OC)cn1 +COc1cccc(C(=O)OCc2ccoc2C)c1OC +CCC(C)C(NC(=O)c1cc(C)nc2c1c(C)nn2C)C(N)=O +O=C(NCCc1ccccc1)c1cccn1-c1cccnc1 +CN(Cc1ccccc1)C(=O)COc1ccccc1NC(=O)C1CC1 +CC(C)c1cc(NC(=O)C2(C)Oc3ccc(Cl)cc3NC2=O)on1 +COCc1cc(CNC(=O)c2ccc3oc(C)cc3c2)n[nH]1 +CCNC(=O)N1CCN(CC(=O)N2CCCCC2CC)CC1 +CN(CC1CCCCO1)C(=O)CN1C(=O)COc2cccnc21 +CC(=O)NC(C(=O)Nc1nc(C)cs1)C(C)C +CC(=O)NCc1cnn(-c2ccc(C(=O)Nc3ccc(C)cc3)cc2)c1 +O=C(NCCC1C(=O)Nc2ccccc21)Nc1ccccc1 +CC(Oc1cccc(C(C)(C)C)c1)C(=O)C(C#N)c1ccccn1 +CCS(=O)c1ccccc1C(=O)Nc1ccncc1 +CC(=O)Nc1ccc(NC(C)C(=O)NCc2ccc(F)cc2)cc1 +Cc1nc(NC(=O)CCC2CCCC2)sc1C(=O)N(C)C +NC(=O)c1cn(CCc2ccc(F)cc2)c2cccc(N)c2c1=O +CC(C)(C)NC(=O)CCC(=O)c1ccc2c(c1)OCCCO2 +O=C(NCc1ccco1)c1ccc(OCc2cccnc2)cc1 +CS(=O)(=O)NCc1cccnc1OCC(F)(F)F +Cc1nn(C)c(=O)c(C(=O)N(C)CCCOc2ccccc2)c1C +CCn1c(CC2CCN(c3nc(N)nc4[nH]cnc34)CC2)n[nH]c1=O +Cc1cc(NC(=O)C(C)Sc2ccccc2Cl)n(C)n1 +CCN(CC(=O)NCC1(C(N)=O)CCOCC1)c1ccccc1 +COc1ccc(-c2nc(C(=O)NC(C)c3ccccn3)cs2)cc1 +CC(=O)c1ccc(NC(=O)c2ncccc2OC(C)C)cc1C +Cc1nn(C)c(N)c1C1(O)C(=O)N(CC(C)C)c2ccccc21 +CC(=O)NC(CC(C)C)C1NCCc2c(Cl)cccc21 +O=C(CS(=O)(=O)c1ccc(Cl)cc1)NC1CCCCNC1=O +CCN(C(=O)c1cccc(N)c1)c1cccc(C)c1 +COc1cccc(NC(=O)CCC(C#N)c2ccncc2)c1 +COC(=O)CNC1=NS(=O)(=O)c2ccccc21 +Cc1cc(C2CCCN2c2ncccc2C#N)no1 +O=C(COCC1CCOC1)N(Cc1ccc(F)cc1)C1CC1 +CC(=O)Nc1cc(NC(C)C(=O)NC2CCCCC2)ccc1F +Cc1sc2ncnc(N3CCC(C)CC3)c2c1C +Nc1cc(Cl)ccc1N1CCCCC1CCO +O=C(NCc1cccnc1)C(O)(c1ccccc1)c1ccccc1 +CCOc1ccc2c(c1)CN(C(=O)CNC(N)=O)CC2 +Cc1cccc(NCC(=O)Nc2c(C)nn(C)c2C)c1C +CCCC1=C(C(=O)OC)C(c2cccc(F)c2)NC(=O)N1 +Cc1ccc(C)c(OCCC(=O)NC(C)(C)CO)c1C +CCS(=O)(=O)NCc1ccc(C(=O)N2CCCCC2C)cc1 +COc1ccc(C(=O)Nc2ccc(N)cc2OC)c(O)c1 +Cc1ccc(S(=O)(=O)N(C)C)cc1NCc1ccc(F)cc1F +Cc1cc(NC(=O)CC(C)C2CC2)n(CCC#N)n1 +NC(=O)c1c(NC(=O)Cc2ccc(F)cc2)sc2c1CCCC2 +CC1OCCC1C(=O)N1CCC(c2ccc(Cl)cc2)C1 +COc1nn(C)cc1C(=O)NCC(O)c1cn(C)c2ccccc12 +CCOc1ccccc1CNC(=O)CCc1c(C)nc(C)[nH]c1=O +Cc1cnc(NC(=O)NCC2(c3ccccc3F)CC2)s1 +CC(C)(C)N(Cc1cccc(F)c1)C(=O)Cn1cnc(C#N)n1 +Cc1ccc(C)c(C(=O)CSc2nnnn2CC(F)(F)F)c1 +CN(C(=O)c1ccoc1)C1CCN(c2ccccc2Cl)C1=O +Cn1cc(CNc2ccccc2CN2CCOCC2)cn1 +Cc1nc(NCC2CCCO2)c2oc3ccccc3c2n1 +CCCC(=O)NCc1ccc2c(c1)CCN2C(=O)C(C)C +CC(Sc1ccccc1)C(=O)Nn1cnc2ccccc21 +CC(C)(CCC#N)CNc1cnn(-c2ccccc2Br)c1 +N#CCn1ccc(NC(=O)c2cc3cc(Br)ccc3o2)n1 +O=C(NC1CCCN(Cc2ccccc2)C1=O)C1CCCCC1 +Cn1nc(C(=O)N2CCCC2)c2c1CN(Cc1nccs1)CC2 +CSc1ncc(C(=O)NCCCC(N)=O)n1-c1ccccc1 +CC(C)C(=O)Nc1ccc2c(c1)nc(CCNC(=O)C1CC1)n2C +Cc1cccc(NCC(=O)NC(c2ccccc2)C(C)C)c1C(N)=O +O=C1CN(C(=O)c2ccc(CNC3Cc4ccccc4C3)cc2)CCN1 +CC(NC(=O)c1ccccc1)C(=O)Nc1cccc(Cl)c1 +COc1cccc2ccn(CC(=O)N3CCN(c4ccccc4)CC3)c12 +Cc1ccc(C(O)CNC(=O)c2ccc(Cl)cc2Cl)o1 +CCc1nc(CNc2ccc(C)cc2OCC(=O)N(C)C)no1 +COc1ccc2cc(NC(=O)Cn3nc(C)c(Cl)c3C)cnc2c1 +COC(=O)C(NC(=O)Cc1cccc(Br)c1)C(C)C +CCc1nnc(NC(=O)c2ccc(C(C)C)nc2N)s1 +COCc1ccc(CNC(=O)C(C)Cc2ccccc2F)cc1 +CC1(C)CCN(C(=O)NC2CCCN(C(=O)OC(C)(C)C)C2)C1 +O=C(c1cnn(C(=O)Cc2cccs2)c1)c1cc(F)ccc1O +CC(NC(=O)Nc1ccc(C(N)=O)cc1)c1cccc2ccccc12 +CCc1cccc(NC(=O)N2CCC(C(=O)N(CC)CC)CC2)c1 +CCN(c1ccc(C(=O)NCCc2ccccn2)cn1)C(C)C +Cc1n[nH]c(C)c1CNC(=O)CCCOc1ccc(Cl)cc1 +CCCN(CC(=O)OC)C(=O)c1cncc(Br)c1 +COCCC(=O)NCc1coc(-c2ccc(C)cc2)n1 +COc1ccccc1OC(=O)C1CC(=O)N(CC(F)(F)F)C1 +NC(=O)c1cnn(-c2nc3ccccc3s2)c1N +COc1ccnc(N2CCN(C(=O)c3ccc(Cl)cc3O)CC2)n1 +CC(C)c1cc(CNC(=O)c2ccc(OCC(F)F)nc2)on1 +CC(C)N(C(=O)c1[nH]ncc1Br)C1CCC1 +CCOCCNC(=O)Nc1nn(-c2ccccc2Cl)cc1C +COc1ccccc1NCC(=O)Nc1nnc(C)s1 +N#Cc1ccc(Br)cc1Br +COc1ccc(F)c(NC(=O)CNC(=O)CC2CCCCC2)c1 +CCCSc1nc(C)c(CCOC(C)=O)c(=O)[nH]1 +COc1ccc2c(c1)CCCC2CNC(=O)NCC(C)(C)O +O=C(Nc1ccncc1)C1(c2cc(-c3ccc(Cl)cc3)on2)CC1 +CCC(Nc1ccc(C(N)=O)cc1)c1ccccc1 +CN(CCNS(=O)(=O)c1ccccc1F)c1ccccc1 +Cc1cc(NC(=O)CSc2nnnn2-c2ccccc2F)no1 +Cc1cc(=O)[nH]c(-c2ccc(NC(=O)C(C)OCC3CC3)cc2)n1 +CC(C)C(=O)Nc1ccc(C(=O)Nc2ccccc2)cc1 +CCOc1ccc(CNC(=O)c2cc(C)nn2CC)cc1 +CCOC(=O)c1ccc(OCc2cscn2)cc1 +CCN(Cc1ccco1)C(=O)c1ccc(C)[nH]c1=O +COc1ccc(C2(C(=O)NC(C)(C)CO)CC2(C)C)cc1 +COCCN1CC(C(=O)Nc2ccc(-n3ccnc3)cc2)CC1=O +CCc1nc2n(n1)CCCC2NC(=O)c1oc2c(C)cccc2c1C +Cc1cc(NC(=O)CSc2ccc(-n3cccn3)nn2)no1 +CC1CCN(C(=O)NC2CCCN(S(C)(=O)=O)C2)CC1 +O=C(CSc1nc2ccccc2o1)Nc1ccc2[nH]c(=O)[nH]c2c1 +O=C(CCc1ccccc1)Nc1ccc(N2CCOCC2)cn1 +Fc1cc(F)c2c(c1)CCNC2CC1=CCCCC1 +O=C(NCC(F)F)Nc1ccc(Oc2cccnc2)nc1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)NCC2CCCO2)c1C +CN(C)c1ncnc2c1CCN(C(=O)Cc1ccc(F)cc1)CC2 +O=C(NCc1cccc2cccnc12)Nc1cccc2c1OCCO2 +CC(C)CCNC(=O)C(C)S(=O)(=O)c1ccccc1F +Cc1noc(C(C)C)c1C(=O)NC(C)c1ccccc1F +CCN(CC)C(=O)c1nnn(-c2cccc(F)c2)c1C(F)(F)F +COc1ccc(C2CCCN2c2nc(C3CC3)no2)cc1 +O=C(Cn1ncccc1=O)N1CCc2ccccc2C1 +COCc1nc(Cn2ncc(N(C)Cc3ccccc3)cc2=O)no1 +Cc1cccc(CNC(=O)Nc2ccc(Oc3cccnc3)nc2)c1 +Cc1cc(C)cc(OC(=O)c2cc(C3CC3)[nH]n2)c1 +CC(=O)c1cccc(NC(=O)NCC(C)(O)c2cnn(C)c2)c1 +Cc1nc(NC(=O)c2cc(OCC(=O)N(C)C)n(C)n2)sc1C +O=C(Cc1ccc(F)cc1)Nc1ccc(-c2ccc3nncn3n2)cc1 +CCN(CCC(=O)OC)C(=O)Nc1ccc(F)cc1F +O=S(=O)(Cc1cc(F)cc(F)c1)c1ccc(Cl)cc1 +Cc1nc(N2CCc3nnc(C(C)C)n3CC2)c2cccnc2n1 +Cc1cc2c(=O)n(Cc3ccccc3C(F)(F)F)cnc2s1 +CN(C)C(=O)c1ccc(N2CCCC2c2ccccc2)nc1 +CNc1cc(CC2CCN(c3cc(C)ncn3)CC2)ncn1 +Cn1cnnc1C1CCCN(Cc2ccc(-c3ccccc3)o2)C1 +COc1cc(C(C)NC(=O)c2ccncc2)ccc1OC(C)C +CC(C)(CNC(=O)N1CCOCC1C1CC1)c1ccncc1 +Cc1c(Cl)c(-c2nnc(-c3ccncc3)o2)nn1C +CC(C(=O)NCc1cccs1)N1CCOC(C(N)=O)C1 +COc1ccc2c(=O)c(-c3csc(C)n3)coc2c1OC +COC(=O)C(C)CN(C)Cc1cc(Cl)ccc1F +c1ccc(-n2c(-c3ccncc3)nnc2-c2cccs2)cc1 +CCN(CC)S(=O)(=O)c1cccc2c1CCNC2 +Cc1c(C(=O)OCC2CCCO2)nnn1-c1cccc2cnccc12 +O=C(CN1CCN(C(=O)CO)CC1)NCC1CCCCC1 +CCc1ccccc1OCC(=O)Nc1cc(OC)ccn1 +Cc1ncsc1CCN(C)C(=O)Cn1c(C)nc2ccccc21 +COc1ccc(NS(=O)(=O)N2CC(C)OC(C)C2)cc1F +O=C1CCCc2[nH]c(=O)c(C(=O)N(Cc3ccccc3)C3CC3)cc21 +O=C(CC1CCCCC1)N1CCN(Cc2ccc(CO)o2)CC1 +Cc1ccnc(NC(=O)c2c(C)nn(-c3ccccc3)c2C)n1 +Cc1ccccc1CC(=O)N1CCN(C(=O)NCC2CCCO2)CC1 +Cc1cccc(-c2nnc(NC(=O)c3cc(C)nn3C)o2)c1 +O=C(COc1cccc(Br)c1)NCC1CCCO1 +c1ccc(C2Cc3ccccc3CN2Cc2cnc3cnccn23)cc1 +O=C(NC1CCCCC1)c1ccnn1Cc1ccccc1 +O=C(NCc1nc(-c2ccncc2)cs1)c1ccnc(F)c1 +Cc1ccc(S(=O)(=O)NCC(=O)c2cccs2)cc1 +O=C(Nc1ccc(OCC2CCOCC2)cc1)N1CCCC(CO)C1 +O=C(CCC(=O)N1CC(=O)Nc2ccccc21)NCc1ccco1 +Cc1cc(C2CCCN(C(=O)C3Cc4cccc(F)c4O3)C2)n[nH]1 +Cc1cnc(-c2nc(-c3cccc(N)c3)cs2)cn1 +O=C(Nc1nnc(SCC2CC2)s1)C1CC1 +O=S(=O)(c1ccc(F)cc1)N1CCC2(CC1)CC2 +O=C(NCCCN1CCCC1=O)Nc1ccc(OC(F)F)cc1 +CC(Nc1cccc(NC(=O)CO)c1)c1c(F)cccc1F +COC(=O)Cc1csc(NC(=O)c2ccc(F)cc2F)n1 +Cc1cc(F)ccc1C(N)c1nc2c(s1)CCC2 +CC(=O)Nc1cc(Cl)ccc1NCc1ccccc1C#N +CCC1CCCCN1C(=O)C1CCN(c2ccc3nncn3n2)CC1 +CC(=O)Nc1ccc(NCc2cccc(C#N)c2)cc1 +OCCCc1csc(CCOc2cccc(Cl)c2)n1 +CC(C)c1ncc(C(=O)NCCCCc2ccccc2)cn1 +CCN(CC(O)c1ccc(C)cc1)C(=O)c1cc(C(C)C)nn1C +Cc1cccc(C(C)CNC(=O)c2cn(CC(=O)N(C)C)nn2)c1 +CC(C)c1nnc(NC(=O)C2CC(=O)N(c3ccccc3F)C2)s1 +O=C(c1cnc2ccccn2c1=O)N1CCC(Cc2ccccc2)CC1 +CCc1nc(-c2ccc(C(=O)Nc3cccc(C(C)=O)c3)cc2)no1 +CNC(=O)Cc1ccc(NC(=O)c2ccccc2F)cc1 +CCc1ccccc1NC(=O)CC(NC(C)=O)c1ccccc1 +Cn1cc(CNC(=O)N2CCCC2c2ccccc2Cl)cn1 +N#CCCCNS(=O)(=O)c1c(F)cc(F)cc1Br +Cn1ccnc(Oc2ccc(Br)cc2)c1=O +NC(=O)Cn1nc2n(c(=O)c1=O)CCN2c1ccccc1 +COCCn1cc(NC(=O)NC(C)c2ccc(C#N)cc2)cn1 +CC(=O)c1cc(C(=O)N2CCCN(c3ccccc3C)CC2)cs1 +CC1(C)CN(C(=O)CC2CC3CCC2C3)CCO1 +CC(C)OCC(=O)NC1(c2ccc(Cl)c(Cl)c2)CC1 +COc1ccc(C(=O)NCCc2nc(-c3ccccc3)cs2)cc1 +CCCn1ccnc1SCC(=O)Nc1ccc2c(c1)CCC2 +CCC(Sc1ccc(N)cc1)C(=O)NC(C)(C)C +Cc1cnc(NC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)s1 +CCn1c(CN2CCOC(Cn3cccn3)C2)nc2c(F)cccc21 +CC(C)C(=O)NCC(=O)N1CCN(c2ccc(Cl)cc2)CC1 +Cn1nc(C(=O)NCc2ccc3c(c2)OCCO3)ccc1=O +Cc1ccc(-c2ccc(C(=O)NCc3cccnc3)c(=O)[nH]2)cc1 +CCN(CC)S(=O)(=O)CC(=O)Nc1ccc2c(c1)CCC2 +O=C(Nc1cc2c3c(c1)CCC(=O)N3CCC2)c1ccc(Cl)cc1 +COC1CCC(CC(=O)NCCCc2n[nH]c(=O)[nH]2)CC1 +Cc1ccc(C(C)(C)C(=O)OCCNc2cccnn2)cc1 +Cn1cncc1Cn1ccc(-c2cccc(-c3cncnc3)c2)n1 +COC(=O)c1cnc2cc(OC(F)(F)F)ccn12 +CSc1ccc(OC(C)C(=O)N(C)CCC#N)cc1 +Cc1ccc(NC(=O)CN(C)C(=O)c2cc(C)ccc2O)nc1 +O=C(Nc1nnc(C(F)(F)F)s1)N1CCCC1c1ccsc1 +COc1ccc(-c2n[nH]c(CNC(=O)OC(C)(C)C)n2)cc1 +Cn1cnc(S(=O)(=O)NCCc2ccc(Cl)cc2)c1 +CC(C)CCN(C)C(=O)NCCS(=O)(=O)c1ccccc1 +CC(C)(C)c1ccc2c(c1)CNCC2NC(=O)c1cccc(N)c1 +Cc1nc(N2CCCCCC2)ncc1C(=O)N1CCCCCC1 +CCOC(=O)Cc1nnc(NC(=O)OCC)s1 +NC(=O)C1(NC(=O)CCc2cccnc2)CCCCC1 +O=C1COc2ccc(C(=O)CSc3ccc(Cl)cc3)cc2N1 +COc1ccc(C)cc1NC(=O)CNC(=O)c1ccc(F)cc1 +O=C(C1CC1c1cccc2ccccc12)N1CCC(CO)C1 +CCN1C(=O)COc2ccc(-c3csc(NC(C)=O)n3)cc21 +CCCn1c(SCC(N)=O)nnc1-c1csc(C)c1C +CCC(C(=O)NCc1cccnc1)N1C(=O)CCCc2ccccc21 +CC(=O)c1cccc(NCC(=O)Nc2cccc(C(C)=O)c2)c1 +CN(C)C(=O)c1ccc2ncnc(N3CCCC3)c2c1 +CCN1CCN(C(=O)c2cc3cnn(C)c3nc2N)CC1 +CC(NC(=O)NCCCn1cccn1)c1ccc2c(c1)CCC(=O)N2 +Cc1cccc(C)c1NC(=O)c1ccc(N(C)S(C)(=O)=O)cc1 +CCn1c(CN2CCC(C(=O)NC3CC3)CC2)nc2cc(F)ccc21 +CS(=O)(=O)N1CCCC1c1ccccc1C(F)(F)F +Cc1cc(C)n(-c2ccc(NC(=O)C3CCCO3)cc2F)n1 +COc1ccc(NC(=O)CNC(=O)c2ccco2)cc1Cl +Cc1cc(S(=O)(=O)NCc2ncn(C)n2)c(C)s1 +CCCN(CC1CC1)C(=O)Nc1ccc(-c2nnnn2C2CC2)cc1 +COC(=O)Cc1csc(NC(=O)N(C)Cc2cc(C)on2)n1 +Cc1c(CN(C)C(c2ccccc2)C(F)(F)F)cc(C#N)n1C +CN(C)S(=O)(=O)N1CC2CCCC2(COCC2CCOCC2)C1 +O=C(CNc1ccc(F)cc1F)Nc1ccccc1F +Nc1nc(SCCCCOc2ccc(Cl)cc2)n[nH]1 +Cc1cc(C)n(CCc2c[nH]c3ccccc23)c(=O)c1C#N +O=C(CCc1nc(C2CCCC2)no1)Nc1cccc(Cl)c1O +CCNC(=O)CN(C)S(=O)(=O)c1ccc(F)cc1 +COC(C(=O)OCc1ccc(C#N)cc1)c1ccccc1 +CC(NC(=O)c1ccc(NC(N)=O)cc1)c1cccc(Cl)c1 +CC(C)(CNC(=O)NCc1ccco1)c1ccc2c(c1)OCO2 +CCC(Cc1ccc(C)cc1)N(C)C(=O)CNC(=O)NC +CC(=O)c1ccc(Oc2cccc(F)c2C#N)cc1 +Cc1ccc(-c2cc(C#N)nn2CCCC#N)cc1 +Clc1ccc(-n2nnnc2Sc2ncnc3sccc23)cc1 +CC(=O)c1cccc(S(=O)(=O)N2CCOC(c3ccccc3)C2)c1 +CC(NC(=O)COC(=O)c1n[nH]c2ccccc12)c1ccccc1 +N#CCCCn1nc(C#N)cc1-c1ccc(F)c(F)c1 +O=C(CCCC(=O)N1CCCC1)c1ccc2c(c1)CCC2 +COc1ccnc(NC(=O)c2cncn2-c2ccccc2)c1 +CSc1ccccc1NC(=O)C(NC(C)=O)C(C)C +CCc1nc2c(cnn2C)c(=O)n1-c1ccccc1Cl +C#CCNC(=O)COC(=O)C(C)NC1=NS(=O)(=O)c2ccccc21 +CCOC(=O)c1c(C)c2c(=O)[nH]cnc2n1-c1ccccc1 +Cc1cc(C)cc(N(CCC#N)C(=O)CSc2ccc(O)cc2)c1 +CC(=O)c1cccc(NC(=O)C2CC(=O)N(C3CC3)C2)c1 +CC(C)Sc1nnc(C2CC2)n1Cc1ccco1 +CC(C)C(CCO)NS(=O)(=O)c1cc(F)ccc1F +Cc1noc(C)c1CS(=O)(=O)c1ccccn1 +CCOC(=O)c1sc(NC(=O)CSc2ccccn2)cc1C +O=C(CCN1CCc2ccccc21)Nc1ccnn1C1CCCC1 +CCOc1cccc(NC(=O)Nc2cnn(CC3CC3)c2)c1 +Nn1c(SCCc2ccccn2)nnc1-c1ccc(Cl)cc1 +CCCC1CN(C(=O)C(NC(=O)c2ccccc2)C(C)CC)CCO1 +CC1CCCC(C)N1C(=O)COC(=O)Cc1c[nH]c2ccccc12 +N#Cc1cc(Br)ccc1N1CCN(c2cccnn2)CC1 +COc1ccccc1NC(=O)c1cc2cccc(OC)c2o1 +Cc1nn(C)c(C)c1NC(=O)c1ccc(Cl)cc1 +CC(Oc1ccc(F)cc1F)C(=O)N1CCN(C)CC1 +CCOC(=O)CC(NC)C(=O)c1ccc2c(c1)CCC2 +Cc1nccn1-c1cncc(C2CCCN(C(=O)C3CCCC3)C2)n1 +CCn1c(SCc2cccc(OC)c2)nnc1C1CC1 +Cn1cnnc1-c1ccc(NC(=O)c2ncn(-c3ccccc3)n2)cc1 +CC(C)c1ccc(C(=O)N2c3ccccc3CC2C)c(N)n1 +O=C(Nc1ccc(O)cc1)c1ccc(Br)cc1 +Cn1ccc(NC(=O)c2cc3c(nc4sccn43)s2)n1 +C=CCN(CCc1ccccc1)C(=O)c1ccc(C)nc1C +CCOC(=O)Cc1csc(NC(=O)C(C)c2ccsc2)n1 +COc1ccccc1NC(=O)C(C)S(=O)(=O)c1cc(C)ccc1C +CCC(Nc1ccnc(C(C)(C)C)n1)c1nc(C)n[nH]1 +CCCNC(=O)c1ccccc1NC(=O)C(OC)c1ccccc1 +Cc1ccc(-c2cnc(CCC(=O)OCc3nc(C)no3)o2)cc1 +COCCNC(=O)Nc1ccc(OC)c(Cl)c1 +CC(C)CNC(=O)CNc1cccc(Br)c1 +CN(C)c1cnn(CCS(=O)(=O)c2ccccc2)c(=O)c1 +CC1CNc2cc(S(=O)(=O)N3CCCCC3C)ccc2O1 +O=C(CC1COCC2CN(Cc3nccs3)CC12)N1CCCC1 +CCS(=O)(=O)c1ccc(CNC(=O)c2cccc3[nH]ccc23)cc1 +CC(C)(C)n1cc(C(=O)Nc2ccccc2O)cn1 +O=C(Nc1cccc(F)c1)c1c(F)ccc2cccnc12 +Cn1cc(C(=O)Nc2cc(C(C)(C)C)nn2C(C)(C)C)ccc1=O +Cn1ccc(C(=O)Nc2sc(-c3ccccc3)cc2C(N)=O)n1 +CSc1cccc(NC(=O)NC2CCC3(C2)OCCO3)c1 +CC(C)c1noc(Cn2nc3c(cc2=O)CCCC3)n1 +CC(=O)Nc1ccc(-c2cn(-c3cccc(N)c3)nn2)cc1 +CC(C)c1noc(C(C)Sc2ccc(C(=O)N3CCCC3)cn2)n1 +COCCCNC(=O)CN(C)C(=O)c1ccc(Cl)cc1Cl +CNc1c(F)cc(C(=O)NCCC(N)=O)cc1F +Cn1cc(C(=O)N2CC(Oc3ccccc3Cl)C2)ccc1=O +O=C(Nc1ccc(NC(=O)c2ccco2)cc1)c1cc[nH]c1 +COc1cccc(NC(=O)CSc2nc(C)cc(C)c2C#N)c1 +CC(=O)Nc1ccc(C(=O)CSc2nccc(=O)[nH]2)cc1 +CNC(=O)C(CC(C)C)NC(=O)Nc1ccc2c(c1)CCN2C(C)=O +Cc1nc(CCNC(=O)C(C)Oc2ccccc2Cl)cs1 +CC(NC(=O)c1cccc(C#N)c1)c1nc(-c2ccncc2)cs1 +Cc1cnn(C(C)C2CC2)c1NC(=O)c1ccnc(-n2cnnc2)c1 +CN(C)S(=O)(=O)N(Cc1cccc(F)c1)C1CC1 +CC1=CC(C)=NC(=O)C1CNC(=O)c1ccc(=O)[nH]c1 +Cc1nn(-c2ccccc2)nc1C(=O)NC1CCc2ccccc21 +Cn1c(-c2ccccn2)nn(CCNC(=O)NC2CCCCC2)c1=O +CCn1cc(N)c(C(=O)NCCn2cc(Br)cn2)n1 +Cc1nc2ccccc2c(=O)n1CCCC(=O)N1CCNC(=O)CC1 +COc1ccc2[nH]c(C)c(CN3CCOCC3)c(=O)c2c1 +CCN(CC)S(=O)(=O)NCc1noc(-c2cccs2)n1 +CNC(=O)c1cccc(NCc2cccc(F)c2F)c1 +CCn1ccnc1-c1nccn1Cc1ccccc1OC +CC(=O)Nc1cccc(NCc2cc(=O)n3cc(C)ccc3n2)c1 +CC1CC(C)CN(C(=O)CN2CCn3c(nn(C)c3=O)C2)C1 +CC1CN(CC(O)Cn2nc(-c3ccccc3)ccc2=O)CC(C)O1 +O=C(NCC(=O)N1CCCC1)c1ccnc2cccnc12 +COc1ccc(C2CC3(C)NC(=O)C2C(=O)N3)c(OC)c1 +CC1CN(CCOc2ccc(C#N)cc2)CC(C)O1 +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1ccccc1 +NC(=O)c1csc(C(=O)N(Cc2ccc(Cl)cc2)C2CC2)c1 +COC(=O)CCN(C)C(=O)c1ccc(Cl)cc1F +CN(CCC(=O)Nc1cccc(C(F)(F)F)c1)Cc1cnccn1 +COCCN(C)C(=O)NCc1cccc(COC)c1 +O=C(c1cscn1)N1CCOC2C(OCc3ccncc3)CCC21 +CC(C)n1cc(Br)cc1C(=O)N(C)CCC#N +Cc1nn(C)c(C)c1CC(=O)OCC1CCN(CC(F)(F)F)CC1 +O=C(Cn1ccc(=O)[nH]c1=O)NCCc1ccc(Cl)cc1Cl +CCCn1c(NCc2ccc(OC)cc2)nc2c(C)nn(C)c2c1=O +Cc1csc(CNc2cc(C(=O)NCC(F)(F)F)ccc2C)n1 +COc1cc2nc(NC(=O)c3snnc3C)sc2cc1OC +COc1cc(C#N)ccc1OCC(=O)Nc1c(C)nn(C)c1C +CC(=O)N1CCc2ccccc2C1CC(=O)N(C)CC(=O)N(C)C +CCCc1ccc(C(O)CN2CC(C)OC(C)C2)cc1 +COc1cccc(CNC(=O)c2cccnc2SC(C)C)c1 +CCCC(=O)Nc1ccc(NC(=O)C(C)C)c(OC)c1 +O=C(CC1Sc2ccccc2NC1=O)NCCCO +CC(C)(NC(=O)c1cc2ccc(Br)cc2[nH]1)C(N)=O +CN(C)C(=O)COCC1CN(Cc2cccnc2)Cc2ccnn2C1 +CN(C)S(=O)(=O)c1cncc(Br)c1 +CCCN(CC(=O)OCC)C(=O)c1cc(Cl)ccc1Cl +CC1CCN(S(=O)(=O)CCCCC#N)C(C)C1 +O=S(=O)(Nc1ccccc1)c1ccc2nncn2c1 +O=C(NCc1cscn1)c1ccc(OCC(F)F)nc1 +CN(Cc1cccc(Cl)c1)C(=O)NCc1nnc2ccccn12 +O=C(Cc1ccc2c(c1)CCCC2)NC1c2ccccc2CC1O +Cc1cc(NCCNC(=O)C#Cc2ccccc2)n2ncnc2n1 +Cc1nc(C)c(CC(=O)NCC2CC=CCC2)c(=O)[nH]1 +CCCc1nnsc1C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +O=C(NCc1ccoc1)Nc1cccc(OCc2cccnc2)c1 +Cc1nc(-c2ccc(NC(=O)c3ccoc3)cc2)cs1 +CC(NC(=O)c1c(-n2cccc2)sc2c1CCCC2)C(N)=O +Nc1cc(N)nc(SCc2cc(Cl)c3c(c2)OCCCO3)n1 +CCN(CC)C(=O)c1cccc(NC(=O)c2cccs2)c1 +CN(C)C(=O)CN1CCc2cc(Br)cc(F)c21 +COc1cc(C(=O)N(C)C2(C#N)CCC2)ccc1OCCC(C)C +O=C(Nc1cnc(-c2cccc(O)c2)nc1)c1scnc1C1CC1 +COC(=O)c1c(N)n(-c2ccc(O)cc2)c2nc3ccccc3nc12 +CC(C)(C)c1n[nH]c(SCc2cc(=O)oc3cc(O)ccc23)n1 +CCCNC(=O)c1cccc(CNC(=O)c2cn3cccnc3n2)c1 +Nc1cccc2c1c(=O)c(C(=O)NCCO)cn2C1CC1 +CC(C)C(=O)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +Cn1c(=O)oc2cc(NC(=O)N3CCCCCC3)ccc21 +COc1ccc(OC)c(CNC(=O)c2cccc(-n3cnnn3)c2)c1 +O=C(C1CC1c1ccc(F)cc1)N1CCCC(CN2CCOCC2)C1 +CCCN(C)C(=O)c1cccc(NC(=O)C2CC2C)c1 +CC(CO)NS(=O)(=O)Cc1ccc(C#N)cc1 +Cn1cc(C2CN(Cc3cccc4c3OCCCO4)CCO2)cn1 +Cc1ccc(N2CCOC2=O)c(-c2ccc(C(N)=O)c(Cl)c2)c1 +Cc1cc(O)cc(O)c1-c1n[nH]c(C)c1Oc1ccccc1 +COC(=O)C(NC(=O)c1ccncc1Cl)c1ccccc1Cl +COc1ccccc1Nc1nnc(SCCC#N)s1 +CC(C)CC(=O)N1CCC(Nc2cccnc2)CC1 +CC(C)(C)OC(=O)N1CCC2(CC1)CNc1ccc(F)cc12 +Cc1ccc(C(=O)NCCS(N)(=O)=O)cc1N +Cc1noc(NC(=O)c2ccc(-n3cncn3)cc2)n1 +C=C(C)Cn1nnc(CO)c1COc1cccc(OC)c1 +O=C(CNC(=O)Nc1ccc2c(c1)CCC(=O)N2)NCc1ccco1 +Cc1nc2cc(Br)ccc2n1C(C)C +COCC(C)OC(=O)c1cc(-c2ccccc2)nc2c1c(C)nn2C +CN(CC(=O)NC(C)(C)C)C(=O)CCc1cc(F)ccc1F +N#Cc1c(-c2ccc(Cl)c(Cl)c2)nn2cccnc12 +CC1CN(C(C)(C)CNC(=O)NCc2ncn(C)n2)CC(C)O1 +CC(NC(=O)CNC(=O)c1cc(F)cc(F)c1)c1ccccc1 +CCOc1ccccc1-c1nnc(-c2nonc2N)o1 +O=C(Nc1nnc(C(F)(F)F)s1)c1c[nH]c2cccc(F)c12 +O=c1nc(N2CCOCC2)ccn1C(c1ccccc1)c1ccccc1 +CCN(Cc1nc(-c2ccccc2)no1)C(=O)c1cccc(OC)c1 +Cc1ccc(OCC(C)NS(=O)(=O)N(C)C)cc1 +O=C(NCCc1cccnc1)NC1CCc2c(Cl)cccc21 +Cc1ccn(-c2ccccc2NC(=O)NC2CCc3[nH]ncc3C2)n1 +CC1CC(C)CN(S(=O)(=O)NCc2ccc(F)cc2)C1 +Nc1ccc(F)cc1C(=O)NCc1ccccc1F +COCCCn1c(SCc2ccc(F)c(F)c2)n[nH]c1=O +Cc1nc(-c2ccc(Br)cc2)c(C)c(=O)[nH]1 +COCCn1cc(NC(=O)NC(C)c2cc(F)ccc2OC)cn1 +c1cc2c(cc1-c1csc(CN3CCOCC3)n1)OCO2 +CCOCCC1(c2nc(-c3ccncc3)no2)CCCC1 +Cc1ccccc1COC1CN(C(=O)CN2CCNC2=O)C1 +O=C(NCc1ccco1)c1ccc(NC(=O)c2ccncc2)cc1 +O=S(=O)(NC(C1CC1)C1CC1)c1ccc2c(c1)CCC2 +Cc1cc(NC(=O)c2cc(F)ccc2F)ccc1C(=O)NC(C)C +Cc1ccc(NC(=O)NCc2ccncc2)cc1S(C)(=O)=O +CCCN(CCC)C(=O)NC1CCC2(CC1)OCCO2 +O=C(Nc1ccc(Cl)c(Cl)c1)C1CCCO1 +O=C(NCc1cc(Cl)ccn1)Nc1cnn(Cc2ccccc2)c1 +CCN(Cc1ccccc1)C(=O)c1ncn2c1C(=O)NCC2 +CCc1c(C(C)=O)[nH]c(C)c1C(=O)c1ccccc1 +C=C(C)Cn1c(NCc2ccco2)nc2c1c(=O)[nH]c(=O)n2C +CC(C)CN(C)C(=O)Nc1nc(-c2ccc[nH]2)cs1 +CN(CC(=O)N1CCc2cc(F)ccc2C1)S(C)(=O)=O +CC(C)(C)OC(=O)NCc1cn(CC(N)=O)nn1 +COc1cc(NC(=O)c2ccc(C#N)cc2)cc(OC)c1OC +COc1c(O)c(Br)cc2c1C(CO)NCC2 +CNS(=O)(=O)c1ccc(NCC2CCCC2)cc1 +O=c1[nH]nc(CN2CCOC(c3ccccc3Br)C2)[nH]1 +O=C(NCc1ccco1)N1CCOC(c2ccc(Cl)cc2)C1 +O=C(CSc1nnc(N2CCCC2)n1C1CC1)Nc1ccncc1 +COCCNS(=O)(=O)c1ccc(OC)c(N)c1 +COC(=O)c1ccc(C)c(OCC(=O)Nc2cccc(OC)c2)c1 +CC(=O)c1cc2c(cc1NC(=O)CCc1ccsc1)OCO2 +Cc1nc(N2CCCC2)ncc1C(=O)N1CCCCCC1 +CC(=O)Nc1ccc(C(=O)Oc2ccc3c(c2)OCO3)cc1 +Cc1ccc(N2CCN(CC(=O)Nc3nnc(C)s3)C2=O)cc1 +COC(=O)CCN(CC1CCCO1)C(=O)C1(C)CC1(Cl)Cl +O=S(=O)(c1cccc2cccnc12)N1CCN2CCCC2C1 +COC(=O)c1c[nH]nc1S(=O)(=O)N1CCCC(C)C1 +CC(C)C(NS(=O)(=O)c1ccccc1F)C(=O)N1CCOCC1 +CN(Cc1cccnc1)C(=O)c1ccccc1N(C)C(=O)C1CC1 +Cc1ccc(CN2CC(C(=O)Nc3c(C)cccc3C)CC2=O)cc1 +Cc1cc(N2CCCC2c2noc(C)n2)n2ncnc2n1 +Cc1ccc(S(C)(=O)=O)cc1S(=O)(=O)N(C)C +Cc1ncc(CNCc2ccnc(OC3CCC3)c2)n1-c1ccccc1 +Cn1nnnc1SCC(=O)Nc1ccc2c(c1)OCO2 +CC1CC(NC(=O)C2CN(C(=O)c3cnccn3)C2)CC(C)(C)C1 +CC1CCCC(C)N1C(=O)COC(=O)c1ccccc1O +COC(=O)C(C)NC(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCCC1 +C=CCNC(=O)c1cccc(S(=O)(=O)Oc2ccccc2C)c1 +O=S(=O)(NCc1cccc(C#CCO)c1)C(F)F +CC1CC(c2ccc(F)cc2)CN1C(=O)C1CCOCC1 +COc1ccccc1OCC(=O)N(C)Cc1nc2ccccc2s1 +O=C1NC2=C(C(=O)N(CC3CCCO3)C2)C(c2cccc(F)c2)N1 +CC(=O)c1cc(-c2ccc(Br)cc2)n(C)n1 +O=C(CCS(=O)(=O)c1ccc(F)cc1)Nc1onc2c1CCC2 +CCn1cc(NC(=O)NCCC(=O)N(C)C)cn1 +O=C(NCc1ccc2c(c1)OCO2)Nc1ccc(F)cc1 +Cc1sc(-c2ccco2)nc1C(=O)Nc1ccc2c(c1)COC2 +CC(=O)Nc1nc2cc(NC(=O)c3ccccc3Cl)ccc2s1 +O=C(Nc1nnc(COc2ccccc2)o1)c1ccccn1 +COc1cc(OC)c(-c2nn(C)c(C)c2N)cc1OC +CCSc1nc2ncc3c(=O)n(NC(=O)COC)ccc3n2n1 +O=C(COc1ccc(-n2cnnn2)cc1)N(C1CCCC1)C1CC1 +CC1CCCCC1NC(=O)Cn1cnc(C2CCC2)cc1=O +Cc1cc(F)ccc1CCNC(=O)NC1CCCC1C(N)=O +CN(C)C(=O)c1cc(NC(=O)N(C)Cc2ccc(F)c(F)c2)ccn1 +O=C(Cc1ccsc1)N1CCC(=O)N(Cc2ccccc2)CC1 +O=C(CCC1CCCC1)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +CCOc1ccc(NC(=O)CNC(=O)c2n[nH]c3ccccc23)cc1 +CC1CCCCN1C(=O)COc1ccc2ccc(=O)oc2c1 +Cc1noc(C)c1S(=O)(=O)NCCCCn1ccccc1=O +COCCN1CCN(C(=O)CCc2ccccc2O)CC1=O +O=C(c1cc[nH]n1)N1CCCC1c1cc(Nc2ccccn2)n[nH]1 +COC(=O)CNC(=O)c1c(C)csc1NC(=O)OC +Cc1cc(S(=O)(=O)NCCCN2CCOCC2)c(C)cc1Cl +CC(C1CC1)n1nccc1NC(=O)CSc1ncn[nH]1 +Cc1ccc(C)c(S(=O)(=O)NCCn2ccnc2)c1 +CC(C)c1nc(S(=O)(=O)NCC2CN3CCCCC3CO2)c[nH]1 +COc1ccc(NC(=O)CC2C=CCC2)cc1S(=O)(=O)N(C)C +CCC(CO)NS(=O)(=O)c1c(C)nn(C)c1C +COCCn1ccc2cc(NC(=O)c3cc(C(C)=O)c[nH]3)ccc21 +CC(=O)Nc1cc(C(=O)Nc2nc(-c3ccco3)cs2)ccc1F +Cc1cn2c(N)c(-c3ccc4c(c3)NC(=O)CO4)nc2s1 +CN(CCC#N)C(=O)CNC1(c2ccc(Cl)c(Cl)c2)CC1 +O=C(c1ccccc1)N1CCN(c2cnn3cnnc3c2)CC1 +CC(=O)OC12c3ccccc3C1CCCC21OCCCO1 +Nc1c(N2CCCC2)c(=O)[nH]c(=O)n1Cc1ccccc1 +Nc1ccc(C(=O)Nc2ccc(C(F)(F)F)cc2)cc1F +O=C(CCC1CCN(C(=O)c2ccoc2)CC1)Nc1ccccc1 +CNS(=O)(=O)c1cc(NC(=O)CCNC(C)=O)ccc1C +COc1cccc(-c2c(CO)nnn2Cc2c(C)noc2C)c1 +CC(=O)Nc1ccccc1OS(=O)(=O)c1cccc(F)c1 +O=C(NCCCO)NCCNC(=O)c1ccccc1 +COc1cccc(C(C)NC(=O)c2c(-c3ccccc3)noc2C)c1 +CC1CCc2sc(NC(=O)c3ccc(Cl)cc3)c(C(N)=O)c2C1 +CN(C(=O)c1ccc(NS(C)(=O)=O)cc1)C1CCCCC1O +Cc1oc(-c2ccccc2)nc1C(=O)N1CCOCC1 +Cn1c(=O)[nH]c(=O)c2c1nc(NC1CCCC1)n2Cc1ccccc1 +CCC1(CNC(=O)N2CCC(OCc3ccccc3F)CC2)CC1 +COc1ccc(F)cc1C(=O)Nc1cccc2cn[nH]c12 +Cn1nnnc1SCC(O)c1ccc(N)cc1 +Nc1c(C(=O)c2ccccc2)cnn1-c1ccccc1 +Cc1cnc(N2CC3CCN(c4cccnc4)C(=O)C3C2)nc1 +CCNC(=O)CN1CCN(C(=O)CCCn2cncn2)CC1 +c1ccc2c(CSc3nnnn3C3CC3)cccc2c1 +CCc1nnc(NC(=O)Cc2cccc(C(F)(F)F)c2)s1 +Cc1ccc2occ(CC(=O)NCc3cccnc3)c2c1 +OC(COc1ccc(F)cc1)CSc1ccccn1 +CCCNC(=O)N1CCC2(CCC(=O)N(Cc3ccncc3)C2)CC1 +Cc1ccc(Cl)cc1S(=O)(=O)NCC(=O)NCc1ccco1 +CNC(=O)Cc1noc(-c2cnc3ccc(C)cn23)n1 +Cc1cccc(OCC(=O)Nc2nnc(-c3ccnn3C)o2)c1 +COC(=O)Cn1c(-c2ccncc2)nc2cc(O)ccc21 +Cc1noc(-c2ccccc2NC(=O)c2ccncc2)n1 +CC(=O)N1CCN(C(C)C(=O)N(C)C2CCCCC2)CC1 +CN(C)S(=O)(=O)c1ccc(C(=O)OCc2ccccc2)cc1 +O=C(Nc1cccc(Cl)c1)c1cc(-n2cnnn2)ccc1Cl +COc1ccc(-c2nn3c(NC(C)C)cc(C)nc3c2C)cc1OC +CC(CN1CCCC1=O)NC(=O)N1CCCC2(CC=CCC2)C1 +CC(=O)Nc1cccc(Nc2ccc(C(C)=O)cc2N)c1 +CCCCOc1cccc(NC(=O)C2CCCN2C(C)=O)c1 +CCn1ncc(C(=O)Nc2ccc(C(=O)OC)cc2)c1C +CC(NC(=O)c1ccc2c(c1)OCO2)c1ccc(F)c(F)c1 +O=C(NCCCNC(=O)c1ccco1)c1cnccn1 +CC(C(=O)Nc1cc(Cl)cc(Cl)c1)n1cc(N)ccc1=O +Nc1cc(S(=O)(=O)NCC(=O)NC2CC2)ccc1O +Cc1ccc(C)c(CN2CC(c3nc(-c4ccco4)no3)C2)c1 +CCCCn1nc(C(=O)Nc2ccc(F)cc2)ccc1=O +CCC1C(=O)NCCN1Cc1nc(-c2ccsc2)oc1C +CCOc1ccc(C2(Cc3ccccc3F)NC(N)=NC2=O)cc1 +CN(C)C(=O)CCc1cccc(NC(=O)c2ccco2)c1 +CCC(NC(=O)c1n[nH]c(=O)c2ccccc12)c1nccs1 +O=C(NC1CCCCCC1)c1ccc2cccc(O)c2n1 +O=C(Cc1ccc(F)c(Br)c1)NCCNC(=O)C1CC1 +Cc1cc(NC(=O)CN2CCN(c3ccc(O)cc3)CC2)on1 +Cc1[nH]c(C)c(S(=O)(=O)NC(C)(C)C)c1C(=O)N1CCCCC1 +O=C(NCc1nnc2n1CCCCC2)c1scnc1C1CC1 +O=C(NCCc1ccccc1F)c1cn(-c2ccccc2)nn1 +Cc1ccc(-n2cnnn2)cc1NC(=O)C1CCC1 +Clc1ccccc1-c1nc(-c2ccccn2)no1 +CCOC(=O)c1ncccc1NC(=O)c1cccc(OC(F)F)c1 +Cc1ccc(C(=O)Nc2ncn(Cc3ccccc3Cl)n2)cc1 +Cn1ccc(C(=O)OCC(=O)Nc2cccc3ccccc23)n1 +CCC(C)NS(=O)(=O)c1ccc(C(C)O)cc1 +CN(C(=O)Cn1c(=O)[nH]c(=O)c2ccccc21)C1CCCCC1 +CCn1c(CN2CCNC(=O)C2)nc2ccccc2c1=O +Cc1ccccc1N1CCN(C(=O)CCCS(N)(=O)=O)C(C)C1 +CCc1cc(C(=O)Nc2ncccc2C)sc1C +CCCCCC(C)NC(=O)Cn1cnc2cc(F)ccc2c1=O +CCc1ncc(C(=O)NC(C)(C)CC(C)(C)C)c(N)n1 +CCN(CC(C)C#N)C(=O)Cn1cc(Br)c(=O)[nH]c1=O +CCC(C)NC(=O)CN1CCN(c2ccc(C)cc2)C1=O +COC(=O)c1cc(F)c(Br)c(F)c1 +COCc1c(Cl)cccc1NC(=O)C1CC1c1ccco1 +CC(c1nc(-c2cccc3[nH]ccc23)no1)n1ccnc1 +CCC1CN(Cc2cccc(OCC(N)=O)c2)CCO1 +CCOC(=O)CC(C)CNC(=O)C1COc2ccc(F)cc2C1 +COc1cccc(C(=O)NCCNS(=O)(=O)c2ccc(C)cc2)c1 +Cc1ccc(F)cc1S(=O)(=O)NCC1CCC1 +CC(Sc1ccccc1Cl)C(=O)NC1CC(=O)N(C)C1 +Cc1ccc2[nH]nc(C(=O)NCC(C)(C)N3CCOCC3)c2c1 +COc1cc(CNn2nnnc2N)ccc1OCc1ccc(C)cc1 +Cc1cc(N2CCN(C(=O)c3ccccc3)CC2)nc2nncn12 +Cn1cnnc1C1CCCN(C(=O)NCCOc2ccccc2)C1 +COc1ccc2c(c1)S(=O)(=O)N(C(C)(C)C)C2=O +CC1CCC(C(N)=O)CN1C(=O)C1CC1c1ccc(F)cc1 +CC(C)(C)OC(=O)N1CCC(Oc2ccc(Br)cn2)C1 +CCOC(=O)CN(C)C(=O)c1cc2c(s1)CCCC2 +COc1cccc(C(=O)N2CCc3ccc(N)cc32)c1OC +Cc1nc(C2COCCN2C(=O)c2cnoc2)cs1 +c1cc2c(cc1-c1nc3cc4c(cc3[nH]1)OCO4)OCO2 +Cc1nc(-c2cccnc2)[nH]c(=O)c1CC(=O)NCc1cnn(C)c1 +CCC1Oc2ccc(C)cc2N(CC(=O)N(C)CCC#N)C1=O +CCC(=O)NCc1ccc2c(c1)CCN2C(=O)CC +CN(CC(=O)NCc1cnn(C)c1)C1=NS(=O)(=O)c2ccccc21 +CCCc1nnc2sc(COc3ccc(Cl)cc3)nn12 +Cc1ccc(CC(=O)NC2CCN(C(=O)c3ccco3)CC2)s1 +CCC(CC)NC(=O)CNC(=O)c1ccsc1 +CCCc1nc(CN(CC)C(=O)c2cccc3cccnc23)no1 +Cc1cc(F)ccc1NC(=O)c1nn(-c2ccccc2)c(C)cc1=O +COc1cc(OC)cc(C(=O)NCc2ccc(OC(C)C)cc2)c1 +CCOc1ccc(C(=O)NCc2ccco2)cc1OCC +CCn1c(-c2ccc(C)cc2)ccc(C(C)(C)O)c1=O +N#CCCN(CCC(F)(F)F)C(=O)c1cc(-c2ccco2)[nH]n1 +CC(C)(C)c1ccc(NC(=O)CSc2nncn2C2CC2)cc1 +COc1cc(C)c(CNc2cnn(-c3ncccn3)c2)cc1OC +O=C(NCC1COCCO1)c1cc2ccccc2[nH]1 +CC(NC(=O)NCC(O)c1ccc(F)c(F)c1)c1nncn1C +Cc1ccc(S(=O)(=O)Nc2ccc(C(=O)NC3CC3)cc2)cc1C +COc1cc(C#N)c(Br)cc1OCC(N)=O +O=C(Nc1nncs1)c1noc2c1CCCCC2 +CCOc1ccc(N2CC(NC(=O)NCc3ccco3)CC2=O)cc1 +CCOc1ccccc1N1CCN(CC(=O)NC)CC1 +N#Cc1cccc(NC(=O)c2cnc3ccccn3c2=O)c1 +Cc1noc(N)c1C(=O)OC(C)C(=O)NCC(F)(F)F +O=C(Nc1cc(C(F)(F)F)ccc1F)C1CCCN1C(=O)C1CC1 +CCOc1ccc(F)c(C(=O)OCc2ccccc2C(N)=O)c1F +O=C(NCCCO)c1ccccc1-c1ccc(C(F)(F)F)cc1 +Cc1cc(=O)oc2cc(OCCN3CCN(C(=O)CO)CC3)ccc12 +CNC(=O)CN1CCN(C(C)c2nc(-c3ccccc3)no2)CC1 +Cn1c(=O)ccn(CC(=O)NC2CCCc3ccccc32)c1=O +CC(C)Cc1nc2oc3c(=O)n(CC(N)=O)cnc3c2c2c1CCC2 +Brc1cccc(OCCCCN2CCOCC2)c1 +CCCOc1nc(C2CCCO2)nc(NC)c1N +Cc1nc(N2CCCC3(C2)OCCO3)c2c(CC(C)C)csc2n1 +CC(C)(C)c1ccccc1OCC(=O)NCC(O)c1ccco1 +COc1ccc(C2=CCN(C(=O)C3CCCC3)CC2)cc1 +CCn1nc(C=Cc2ccccc2)nc2c(=O)n(C)c(=O)nc1-2 +O=C(Cc1ccccc1)Nc1cc(NC(=O)c2ccccn2)ccc1F +CCn1nc(C)cc1C(=O)Nc1cccc(C(C)=O)c1 +CC(C)CCN(C)C(=O)NC(C)c1cccc(N2CCCC2=O)c1 +CC(C)N1CC(C(=O)NCc2ccccc2Cn2cncn2)CC1=O +COC(C)(C)c1noc(CC2c3ccccc3C=CN2C(C)=O)n1 +COCc1cccc(NS(=O)(=O)c2cccc(C#N)c2)c1 +Cc1ccc(NC(=O)CCn2cnc3oc(C)c(C)c3c2=O)cc1C +COc1cccc(OCC(=O)Nc2ccn(C)n2)c1 +COCc1cc(C(=O)N(C)C2CCCCCC2)ccc1F +COc1ccc(C2(NC(=O)c3ccc(=O)[nH]n3)CCCCC2)cc1 +CN(Cc1ccccc1)C(=O)CNC(=O)C1(C)CC1(Cl)Cl +CCN(CC(=O)NC(C)C)S(=O)(=O)c1cc(C)ccc1OC +COCCn1cc(C(=O)c2cccs2)c2ccccc21 +O=C(CC1CCCC1)N1CCCN(C(=O)NCC2CCCO2)CC1 +N#CC1(NC(=O)CSc2nnc(-c3cccs3)n2N)CCCC1 +CCS(=O)(=O)NCCNC(=O)c1cn(C)nc1C(C)(C)C +Cc1ccc(-c2n[nH]cc2CNCCc2ccc(F)cc2F)o1 +COc1ccnc(NC(=O)Cc2cccc(F)c2)c1 +CC(C)NC(=O)Nc1ccc(CNC(=O)Cc2ccc[nH]2)cc1 +O=C(Nc1ccc2c(c1)COC2)c1ccc(-n2ccnn2)cc1 +CCOC(=O)C1=C(C)N=C2CCCC(=O)C2C1c1ccccc1OC +CC(=O)N1CCCC1C(=O)NCCCn1cccn1 +COc1ccc(C(N)=O)cc1S(=O)(=O)N(C)C +COCC(C)Nc1ncnc(N2CCCCC2C)c1N +Cc1cc(C)n(CC(=O)NCCc2ccc(C)c(C)c2)n1 +CC(NC(=O)Cc1ccc(F)cc1)c1nc(-c2cccnc2)n[nH]1 +CS(=O)(=O)NCC1(c2ccccc2)CCOCC1 +Cc1nc(C2CCCN2C(=O)c2cccc(N3CCCC3=O)c2)no1 +CC(C)(CO)NS(=O)(=O)c1ccc(N)cc1C#N +COC(=O)c1cccc(OCC(=O)N(C)Cc2cnn(C)c2)c1 +COc1ccccc1CNc1nn2c(nc3ccccc32)[nH]1 +CCCn1nnc(CO)c1COc1ccccc1Cl +Cn1cc(CNC(=O)NC(c2ccc(F)cc2)C2CCCO2)cn1 +Cc1cc(NC(=O)Cc2ccc(S(C)(=O)=O)cc2)n(C)n1 +CC(=O)NCCCC(=O)Nc1cccc(F)c1F +CC(=O)c1cccc(S(=O)(=O)NCCC(=O)NC2CC2)c1 +Cc1ccc(C)c(CC(=O)Nc2cc(Cl)ccc2-n2cncn2)c1 +O=S(=O)(NCCn1nc(-c2cccs2)cc1C1CC1)C1CC1 +CCn1ccc(-c2ccc(Br)cc2)n1 +CN1CCOC(CNC(=O)CCCc2ccccc2)C1 +CCN(CC)c1cnn(-c2ccccc2)c(=O)c1Br +CCOc1ccc(C(=O)N(c2cccc(O)c2)S(C)(=O)=O)cc1 +Cc1cc(C)c(C(=O)N2CCC3(CCc4ccccc43)CC2)c(=O)[nH]1 +COc1cccc(C(=O)NC2CCN(C(=O)c3ccoc3)CC2)c1O +O=c1cccnn1CCNS(=O)(=O)CCc1ccccc1 +CN1CCN(c2ncccn2)CC1c1ccccc1 +CC(C)(C)NC(=O)N1CCN(CC(O)c2ccco2)CC1 +CC1Oc2ccccc2OC1C(=O)Nc1ccccc1F +O=C(c1ccncc1)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +CCOc1ccccc1OCC(=O)N(C)Cc1ccc(F)cc1 +COC(=O)c1noc(C(=O)NC(C)c2ccccc2)c1N +CCNC(C)(C(=O)OCC)c1ccc(Cl)cc1 +COc1ccc(-n2ccnc(NCc3ccccc3)c2=O)cc1 +CC(C)(C)c1csc(C2CN(CC3=CCCOC3)CCO2)n1 +COc1ccc(S(=O)(=O)N2CCCC2c2ccco2)cc1 +CC(C)CC(OC(=O)c1cnns1)c1ccccn1 +Cc1nn(C)c(C)c1CCC(=O)OC(C)c1cc(F)ccc1F +CN(C)c1ccccc1C#CCNC(=O)Nc1cccs1 +CC(Sc1ccncc1N)C(=O)NC1CCCC1 +Cc1ccc(N)cc1NC(=O)CSc1ccccn1 +CCn1nc(C)c(Cl)c1C(=O)Nc1sc2c(c1C#N)CCCC2 +COc1ccc(NC(=O)CCSc2nnc(C3CC3)n2C)cc1 +COc1cccc(COCC(=O)N2CCCC(c3ccn[nH]3)C2)c1 +CCCC(CCC)C(=O)Nc1ccc(-n2ccnc2C)nc1 +CCc1nnsc1C(=O)N(C)Cc1ccccc1Br +CC(=O)c1cc(CCC(=O)Nc2ccc(C)cc2)oc1C +Cc1cc(NC(=O)NCc2ncn(C)n2)ccc1Oc1cccnc1 +O=C(CSc1ccc(F)cc1F)NC1CCC(O)CC1 +Cc1cc(C)c(NC(=O)CNC(=O)c2cc[nH]n2)c(C)c1 +CC(=O)c1ccc(NC(=O)NCc2nc(C3CC3)no2)cc1 +O=C(CCn1cccn1)N1CCCC(CCO)C1 +CCOc1ccc(C2(CNC(=O)NCC3CC3)CCOCC2)cc1 +CCc1nc(C2CCCN(C(=O)Cc3cnn(C)c3)C2)no1 +Cc1cc(C(=O)N2CC3COCC3(COc3ccccn3)C2)on1 +Cc1ccc2nc(CSc3ncccn3)cc(=O)n2c1 +COCc1oc(C)c(C)c1-c1nnc(NC(C)C)s1 +COCc1ccc(C(=O)NCC(C)(C)N2CCOCC2)cc1 +CCOc1cccc2sc(NC(=O)C(C)C)nc12 +Cc1cc(NC(=O)NC2CCN(C(=O)c3ccoc3)CC2)no1 +CC(=O)Nc1ccc(-c2cc(C#N)nn2C(C)C)cc1 +Cc1c(F)cc(C(N)=O)cc1NC(=O)c1cccc(C(F)(F)F)c1 +Cc1cc(C)n(C(=O)c2nn(C)c(C(F)(F)F)c2Cl)n1 +NC(=O)CN(c1cc(Br)ccc1CO)C1CCCC1 +Cc1cccc(OCC(C)NC(=O)NCc2cccc(C)n2)c1 +O=C(Nc1ccccn1)c1c[nH]nc1-c1ccc(Cl)cc1 +COc1ccccc1NCC(=O)N(C)C1CCCc2nc(C)sc21 +Cc1noc(C2CCCN(C(=O)COc3ccccc3C)C2)n1 +NS(=O)(=O)N1CCC(C(=O)c2ccc3c(c2)OCCO3)CC1 +Cc1nn2cccnc2c1C(=O)NCCc1cc(Cl)cc(Cl)c1 +CCOC(C)C(=O)Nc1cc(C)nn1-c1ccc(Cl)cc1 +O=C(c1cn(-c2cc(N3CCCCC3)ncn2)cn1)N1CCCCC1 +FC(F)CN1CCN(Cc2cc(Cl)cc3c2OCOC3)CC1 +COc1cc(N)cc2sc(NC(=O)C3CCC3)nc12 +O=C(Nc1nc(CCCc2c[nH]c3ccccc23)n[nH]1)c1ccncc1 +CCOc1ncccc1CNC(=O)c1cnc(N(C)C)nc1C +Cc1cccc(NC(=O)c2cn3cc(N)ccc3n2)c1C +COc1cc(C(N)=O)ccc1Oc1ccc(Cl)cc1N +CC(C(=O)Nc1cc(F)c(F)c(F)c1)c1cccs1 +C=CCNC(=O)c1snc(S(=O)(=O)CCC)c1N +CC(=O)OC1CN(c2nc3ccc(F)cc3s2)C1 +COc1ccc2nc(CC(=O)c3ccccc3OC)[nH]c(=O)c2c1 +COc1cc(NCc2noc(C3CCCO3)n2)ncn1 +CCS(=O)(=O)N1CCCC1C(=O)c1cccs1 +CCn1cncc1S(=O)(=O)Oc1cccc(OC)c1 +O=C(CNC(=O)c1csc(-c2ccsc2)n1)NC1CC1 +CC(C)(C)c1[nH]ncc1-c1n[nH]c2cc(N)ccc12 +COc1ccc(C(C)(C)C)cc1S(=O)(=O)NCCO +COCCCOC(=O)c1csc(NC(C)=O)n1 +O=C(Cc1c[nH]c2ccccc12)Nc1ccc(F)c(F)c1F +CC1CCCCN1C(=O)c1ccc(NC(=O)C2CC=CC2)cc1 +N#Cc1ccc(NC(=O)CCNC(=O)C2CCCC2)cc1 +CC(C)c1nnc2n1CCN(C(=O)C1CCCC(C(F)(F)F)C1)C2 +CC(C)c1ccc(C#N)c(=O)n1CC(=O)NCC1CCCO1 +O=C(CN1CCN(c2ccc(Cl)cc2)C1=O)N1CCCCCC1 +CCNC(=O)Nc1ccc(-c2ncc(C)c(N(C)C)n2)cc1 +CCC(C)C(NC(=O)COc1ccc(Cl)cc1Cl)C(N)=O +COCCn1cc(NC(=O)NCc2ccccc2CO)cn1 +COc1cc(Cl)c(CN2CCOC(C(N)=O)C2)cc1Cl +CCc1oc(C(=O)Nc2c(C)noc2CC)cc1C +CCOC(=O)c1ccc2[nH]c(NCC(O)CO)nc2c1 +Cc1ccc(-c2ocnc2C(=O)Nc2ccccc2F)s1 +CS(=O)(=O)N1Cc2ccccc2CC1C(=O)Nc1ccccc1O +CC1CCCC(NC(=O)N(C)C(C)c2ccncc2)C1 +CC(=O)c1cccc(OC(=O)Cn2ncc3ccccc3c2=O)c1 +Cc1ccccc1OCC(=O)Nc1nnc(-c2ccn(C(C)C)n2)o1 +CCc1nc(CN(C)C(=O)NCc2cccc(NC(C)=O)c2)cs1 +CCCCC(NC(N)=O)C(=O)N(C)CC1CCCC1 +COc1cc(NC(=O)N2CCCC2CO)cc(OC)c1 +COc1c2c(cc3c1C(C#CCO)N(C)CC3)OCO2 +CCOC(=O)C1=C(C(C)C)N(C)C(=O)NC1c1ccc(O)c(OC)c1 +Nc1cc(F)ccc1NC(=O)c1ccc(O)c(Cl)c1 +COc1ccc2cc(NC(=O)CCc3cnn(C)c3C)cnc2c1 +Cc1nc(-c2cnn(-c3ccccc3)c2)c2cc(C)oc2n1 +CCn1c(=O)c2cc(C(=O)N3CCOCC3)sc2c2ccccc21 +COc1ccc(OC)c(CNCCc2ccccc2)c1 +COc1ccc2c(c1Br)C(CC1CC1)NCC2 +CCOC(=O)CCCNC(=O)Nc1ccc(C)cc1C +CCCCn1nc(-c2ccc(C)cc2C)cc(N)c1=O +CCCn1c(SCC(=O)N(C2=CCCCC2)C2CC2)n[nH]c1=O +c1ccc2[nH]c(SCCCc3nc(-c4ccncc4)no3)nc2c1 +Cn1cc(C(=O)NCC2CC=CCC2)c(C(C)(C)C)n1 +Nc1ccc(NS(=O)(=O)c2cccc(F)c2)cc1Cl +CC(=O)OCC1CC2C3CCC(C3)C2C1COC(C)=O +O=C(NCc1nnc2ccccn12)c1csnn1 +CNC(=O)c1cccnc1N1CCC(c2nncn2C(C)C)CC1 +CN1CCCCc2cc(Br)cc(N)c21 +O=c1oc2ccccc2n1CCCN1CCOC(Cn2cccn2)C1 +Cc1[nH]c(=O)sc1S(=O)(=O)N1CCc2c(N)cccc2C1 +Cc1ccc2cc(C(=O)N3CCCC3c3noc(C4CC4)n3)[nH]c2c1 +CC(=O)c1ccc(NC(=O)COc2ccccc2)cc1C +CSc1ncnc(NCc2ccc(Cl)cc2)c1C#N +CSc1ccc(C)c(C(=O)NCc2ccco2)c1 +CSc1nnc(C(=O)c2ccccc2)n1C1CC1 +CN(Cc1nccn1C(F)F)C(=O)Cc1ccc(F)cc1 +Cc1nc2ccc(C(=O)NC3(C#N)CCCCC3)cc2nc1C +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1cc2ccccc2[nH]1 +CCCOc1ccc(C(=O)Nc2ccc(C#N)cc2)cc1OCC +Cc1ccc(NC(=O)CC(C)n2ccc(C)n2)c(C)c1 +Cc1cc2c(cc1S(=O)(=O)NC1CCCC1)OCC(=O)N2 +CCOC(=O)c1cnc(Cc2ccc(OC)cc2)nc1N +O=C(Nc1ccccc1F)c1ccc(OCC2CCCO2)cc1 +CCN(CCOC)C(=O)CCc1ccccc1N +N#Cc1ccc(NC(=O)CCNS(=O)(=O)c2ccc(F)cc2)cc1 +CCCN(CCC)C(=O)COc1ccc(C#N)cc1 +CCn1ccc(C(=O)N2CCN(S(C)(=O)=O)CC2)n1 +O=C(Nc1nnc(-c2ccno2)o1)c1cc(Cl)ccc1Cl +COCc1ccccc1C(=O)Nc1ccc2nc(C)oc2c1 +Cc1cc(N2CCCC(c3noc(C)n3)C2)n2ncnc2n1 +COc1cccc(NC(=O)C(C)CS(=O)(=O)N2CCNCC2)c1 +CC(NC(=O)NCc1cccs1)C1CCCO1 +CCCCS(=O)(=O)NC(C#N)c1ccccc1Cl +Cc1cnc(NC(=O)c2ccc(OCC(F)(F)F)nc2)s1 +Cn1nc(COCC2CC2)c2c1CCN(C(=O)c1ccno1)C2 +NC(=O)CCCNC(=O)c1cc(-c2ccncc2)nc2ccccc12 +COc1ccc(C)cc1S(=O)(=O)NCCOc1ccc(F)cc1 +CC(C)Oc1cccc(C(C)NC(=O)NC2CC2)c1 +O=c1oc(-c2cccs2)nn1CC(O)c1ccccc1 +C#CCOC(=O)C1CCCN1C(=O)OC(C)(C)C +CNC(=O)CN(c1ccccc1C)S(C)(=O)=O +CC(=O)c1cccc(S(=O)(=O)Nc2cccc(COC(C)C)c2)c1 +CS(=O)(=O)N1CCC(NC(=O)c2ccc(-c3cc[nH]n3)cc2)CC1 +Cc1nc(-n2nc(C)c(CCC(=O)N3CCCCC3)c2O)sc1C +O=C(NCc1nc(-c2cccs2)no1)c1cnns1 +COc1ccc(C(=O)NCCc2ccccc2OC)nn1 +Cc1cc(C)c(C(=O)CC2(C(F)(F)F)NCCN2)c(=O)[nH]1 +COc1ccc(CNC(=O)Nc2ccc(NC(C)=O)cc2)cc1F +CCOC(=O)c1cccc(NC(=O)c2cccc(F)c2)c1 +COCCCCCNC(=O)c1ccc(F)cc1Cl +CCCC(C)C(=O)NCc1cccnc1OCC +CC(C)NC(=O)Nc1ccc(CC(=O)Nc2ccccc2F)cc1 +CN(CC(=O)NC1COc2ccccc2C1)c1ncnc2[nH]cnc12 +CCC1CCCCN1S(=O)(=O)c1cccs1 +CC1(NC(=O)CCC(=O)N2CCOCC2)Cc2ccccc2C1 +O=S(=O)(C1CC1)N1CCCn2nnc(Cn3cccc3)c2C1 +CCCCOc1ccc(C(O)C(=O)N(C)C)cc1 +CC(=O)Nc1ccc(C)cc1NC(=O)c1ccc(Cn2cccn2)cc1 +COc1cc(OC)c(NC(=O)N(C)C(C)c2ccncc2)cc1F +C=CCNC(=O)c1cnc(COc2ccccc2)nc1N +CCCCN1CC(C(=O)Nc2ccccc2C)CC1=O +CCn1c(=O)c(=O)[nH]c2cc(C(=O)NCC(=O)NC(C)(C)C)ccc21 +Cc1ccc(Cl)c2sc(N3CCN(S(C)(=O)=O)CC3)nc12 +O=C(Cn1ccc2c(cnc3ccnn32)c1=O)Nc1nccs1 +COCCN(Cc1cc2ccccc2[nH]c1=O)C(=O)c1ccccc1 +NC(=O)CN(C(=O)c1ccccc1O)C1CCCC1 +Cc1ccc2c(c1)N(C(C)C(=O)NCc1cccs1)C(=O)CO2 +O=C(NCc1cccc(C(F)(F)F)c1)c1cc(-c2ccco2)[nH]n1 +O=S(=O)(NC1CCCCC1O)c1ccc(O)cc1 +Cc1cc2c(=O)n(CC(O)c3cccc(F)c3)cnc2s1 +O=C(NC1CNCc2cc(Cl)ccc21)c1cccc(Cl)c1 +COc1ccc2c(c1O)CCNC2c1ncccn1 +CC(=O)c1ccc(Nc2oc(C)cc(=O)c2C(C)=O)cc1 +CC(C)CN1CCOC(CNS(N)(=O)=O)C1 +O=C(NC1CCCCNC1=O)c1csc(-c2ccco2)n1 +Nc1nc(C(=O)NCc2cccc(Br)c2)n[nH]1 +O=C(Nc1cnn(C2CCOC2)c1)c1ccc(C(F)(F)F)cc1 +Cc1nc(-c2cncc(-c3ccsc3)c2)cc(=O)[nH]1 +O=C(CSc1ccncc1)OCC(=O)N1CCCC1 +CSc1cccc(NC(C)C(=O)Nc2ccc(NC(C)=O)cc2)c1 +CN1C(=O)c2cccnc2Sc2cc(NC(=O)C3CC3)ccc21 +O=C(Nc1cc(-n2cccc2)ccc1F)c1c[nH]c2ccccc2c1=O +CCc1onc(C)c1NC(=O)COc1ccc(C(F)(F)F)cc1 +CCC1CCCCN1C(=O)CNc1ccc(F)c(NC(C)=O)c1 +COC(=O)CN(C(=O)Cn1cnc2c(C)cccc2c1=O)C(C)C +CCn1cc(NS(=O)(=O)c2ccc(Br)cc2)cn1 +COc1ccc2c(c1)cc(C)c1nn(CC(=O)N3CCCC3)c(=O)n12 +CS(=O)(=O)c1ccc(NC(=O)NCc2ccoc2)cc1 +COc1ccc(-c2cc(CNC(=O)NC3CCCC3)on2)cc1 +c1csc(-c2nc(CNc3ncnc4sccc34)co2)c1 +Cn1ccnc1C(O)(CCNC(=O)NCc1cc[nH]n1)C(F)(F)F +CNC(=O)c1cccc(OC(=O)c2ccc(Oc3ccccc3)nc2)c1 +O=C(NCCNC(=O)N1CCc2ccccc21)c1ccco1 +Cc1ccc(C(=O)Nc2ccc3c(c2)C(=O)N(C)CCO3)cc1 +CCOCc1cncc2c1CCN(Cc1ccsc1)C2 +Cc1nc(NC(=O)c2cc(-c3ccco3)cs2)sc1C +CCS(=O)(=O)NC(C)CCc1ccc(OC)cc1 +Cc1ccc(CNS(=O)(=O)c2cc(F)cc(F)c2)s1 +O=C1CC(c2cccs2)Cc2nc3ccnn3cc21 +O=C(Oc1ccc2cn[nH]c2c1)c1ccc(C(F)(F)F)nc1 +Cc1c(COC(C)C)cccc1NCc1noc(C2CC2)n1 +O=C(CCOc1ccccc1)N1Cc2cnn(CCO)c2C1 +COc1ccc(CCC(=O)Nc2ccc3[nH]cnc3c2)cc1OC +Cc1csc(-c2ccc(N)c(OCC(N)=O)c2)n1 +CCCc1cc(NCCCn2ccnn2)n2nccc2n1 +CCC(C)c1cc(NC(=O)N(C)C)ccc1OC +CCC(Oc1ccc(C)c(C)c1)C(=O)N1CCOCC1 +O=C(NCc1ccc2c(c1)OCCO2)NCc1ccco1 +CC(C)(CNC(=O)c1cn(Cc2ccccc2)nn1)C(N)=O +CCC(C)NC(=O)Cn1c(-c2ccco2)nc2ccccc21 +Nc1ccc2c(c1)N(C(=O)c1ccc3c(c1)OCO3)CCC2 +CCC(CC)N(C)C(=O)c1[nH]c(C)c(C(=O)OC)c1C +Cc1nc(C(=O)NC(C)CCc2ccccc2)cs1 +CN(C)S(=O)(=O)c1cc(C(=O)OCC2CC2)ccc1Cl +CC(C(=O)N1CCC2(CC1)OCCO2)n1ncn2cccc2c1=O +COc1ccc(OC)c(NC(=O)c2ccc(C)c(O)c2)c1 +CNC(=O)c1cccc(NC(=O)CNc2cccc(C)c2C)c1 +Cc1ocnc1C(=O)Nc1ccc(Br)cc1C(C)C +COCc1noc(-c2cccc(S(C)(=O)=O)c2)n1 +CCOC(=O)c1cncc(Nc2c(F)cccc2F)c1 +COc1cc(Cl)c(NC(=O)NCc2ccn(C)c2)cc1OC +Oc1cccc(CNc2ccc(F)c(Cl)c2)c1 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+CC(C)N1C(=O)Cc2ccccc2C1C(=O)NCc1cccs1 +COCC(C)NC(=O)c1cc(-c2cccc(F)c2)no1 +Cc1cccc(C)c1OCC(O)Cn1cnc2sccc2c1=O +CC(C)c1nnc(NC(=O)C2CC2(Cl)Cl)s1 +CCC(C(=O)OCC(C)C)n1c(C)ccc(C#N)c1=O +CCCNc1nc(-c2sc(C3CC3)nc2C)cs1 +NC(=O)C1CCN(c2nccc(Cl)c2N)CC1 +CC(O)(CNS(=O)(=O)C1CCCCC1)c1ccccc1 +CCn1cc(-c2cc(-c3ccc(OC)cc3)nc(N)c2C#N)c(C)n1 +CC(=O)N(C)c1cccc(NC(=O)COc2ccccc2)c1 +CN(C)C(=O)CN(C)c1nn2cc(-c3ccc(F)cc3)nc2s1 +CCc1c(C(=O)Nc2ccc(OC)nc2)cnn1Cc1ccccc1 +COC(=O)c1cc(S(=O)(=O)Nc2cccc(F)c2)cn1C +N#CC1(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)CCCCC1 +N#Cc1cc(F)ccc1NC(=O)NCc1ncc(-c2ccccc2)o1 +Cc1ccccc1-c1nnn(CC(=O)N(C)C(C)c2ccccc2)n1 +CC(C)Sc1ccc(C(C)NC(=O)Cn2cccnc2=O)cc1 +CCNc1ncc(CN2CCOC(Cc3cccc(OC)c3)C2)cn1 +O=C(COc1ccccc1)OCC(=O)c1cccs1 +Cc1ccccc1NC(=O)C(Cc1c[nH]c2ccccc12)NC(N)=O +Fc1ccc(SCCc2ccccn2)cc1F +COc1cc(C)ccc1OCc1nc(C)cc(N)n1 +CN(CCC(F)(F)F)Cc1nnc2n(C)c(=O)c3ccccc3n12 +Cc1ccc(CC(=O)NCc2ccccc2CN2CCCC2=O)cc1 +C#CC(OC(=O)c1cc(OC)ccc1OC)C1CC1 +CC(NC(=O)N1CCC2(CCCCC2)C1)C(=O)N(C)C +COCc1cc(CNC(=O)c2ccc3c(c2)nnn3C)n[nH]1 +CCOC(=O)CSc1nc(-c2ccccn2)n[nH]1 +Cc1cc(C)n(C(=O)c2ccc(NC(=O)CC(C)C)cc2)n1 +Cc1n[nH]c(C2CN(C(=O)CCOCC(F)(F)F)CCO2)n1 +Cc1csc(-c2coc3cc(O)c(C)cc3c2=O)n1 +C=CCN(CC(F)(F)F)C(=O)Cn1cnc2c(C)cccc2c1=O +COc1ccccc1NC(=O)Nc1cccc2c1CCCN2 +CNC(=O)CN1CCN(C(=O)Nc2cccc(C(C)=O)c2)CC1 +CCOc1ccc(NC(=O)Nc2ccc3c(c2)CC(=O)N3C)cc1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)Nc2nncs2)cc1 +CC(C)c1cc(C(=O)NCc2nncn2C2CCCCC2)no1 +COc1cc(=O)n(-c2ccc(C)cc2)nc1C(=O)NCC(C)C +CC(C)CNC(=O)C1(NCc2cccc(F)c2F)CCCC1 +CC1(C)CN(C(=O)NCc2ccccc2-n2ccnc2)CCO1 +COC(=O)c1c[nH]c(Cc2cccc(Cl)c2)n1 +COCC(NC(=O)c1ccccc1C(=O)c1cccs1)C(N)=O +Cc1ccc(OCCN(C)C(=O)NCCC(=O)N2CCCC2)cc1 +CCC(=O)N1CCc2cc(C(=O)Nc3cccc(C)c3)ccc21 +O=C(Cc1ccc2c(c1)OCCO2)N1CCC(O)CC1 +Cc1csc(-n2nnc(CO)c2CC(C)C)n1 +CN(CCc1noc(C2CCCCC2)n1)C(=O)c1ccco1 +CC(O)CN(C)C(=O)CSc1nc2ccccc2s1 +Cn1cc(C(=O)N2CCC(Oc3ncccc3C#N)CC2)nn1 +NS(=O)(=O)c1ccc(Cl)c(C(=O)Nc2ccc(Cl)cc2)c1 +COc1ccc(C(=O)CSc2nc3n(n2)CCCCC3)cc1 +CNC(=O)NCC(=O)N1CCCCC1c1ccc(C)cc1 +O=C(CCc1ccc2c(c1)OCO2)Nc1cccc(-n2cnnn2)c1 +O=C(Nc1nc2ncccn2n1)c1cnc(-c2ccsc2)s1 +CC(=O)c1ccc(C#CCNC(=O)NCCc2ccccc2)cc1 +CCNC(=O)C(C)OC(=O)c1ccc(Br)cc1F +COC(=O)c1ccc2oc(SCc3cc(=O)c(OC)co3)nc2c1 +O=C(NCc1cccnc1)c1cccc2nscc12 +CC(C)C(=O)NCCNC(=O)c1ccc(N2CCCC2=O)cc1 +CC1CC=CCC1COC(=O)CN(C)S(C)(=O)=O +COC(=O)CCN(CC(C)C)C(=O)c1ccc(C)c(F)c1 +Nc1ccc(-n2cc(-c3ccco3)nn2)c(Cl)c1 +Cc1ccc(NC(=O)CN2CCc3ccccc32)nc1 +CCNC(=O)c1cccc(CNC(=O)c2cc3ccccc3[nH]c2=O)c1 +CCc1ccc2c(c1)C(c1cnc(OC)nc1OC)NCC2 +CCn1nc(-c2nc(Cc3ccccc3Cl)no2)ccc1=O +CCCCCC(=O)Nc1ccccc1C(=O)N1CCCCC1 +CC(=O)c1ccc(-c2cccc3[nH]c(=O)oc23)s1 +Cc1ccc(-c2nc(C(=O)Nc3nc[nH]n3)cs2)cc1 +COc1cc(OC)c(-c2ccc(CO)c(C)n2)c(OC)c1 +CNC(=O)C1CN(c2nc(C)cc(C)n2)CCN1C(C)C +COC(=O)c1c(C)cccc1NC(=O)c1ccccn1 +CC(OCC(F)(F)F)C(=O)Nc1cccc(F)c1 +CC(C)c1cc(C(=O)OC2CCN(CC(F)F)CC2)n(C)n1 +CCc1ccccc1NC(=O)C1Nc2cc(C)ccc2S(=O)(=O)N1 +N#Cc1cccc(OCC(=O)Nc2ccnn2Cc2cccs2)c1 +CCOC(=O)Cn1c(=O)cc(-c2ccccc2)oc1=O +CC(C)n1ccc(C(=O)Nc2nnc(-c3cc4ccccc4o3)o2)n1 +COc1ncccc1NC(=O)CNC(=O)N1CCc2ccccc2C1 +CCNC(=O)c1ccc(C)c(NC(=O)N(C)Cc2ccccc2F)c1 +CCCC1CN(Cc2ccccc2N2CCOCC2)CCO1 +Cc1ccccc1-n1ccnc1SC(C)C(=O)NCC1CCCO1 +CCNC(=O)N1CCN(Cc2cccc3ccccc23)CC1 +CC(C)(C)NC(=O)CNc1ncc(C(F)(F)F)cc1Cl +COc1cc(NC(=O)C(OC)c2ccccc2)c(OC)cc1Cl +Cc1cc(OC(=O)C(C)OCC2CCCO2)cc(C)c1Cl +CCCn1nnnc1Cn1nnc(-c2cccc(OC)c2)n1 +O=C(c1cnccn1)N1CCCC(c2nnc(-c3cccs3)o2)C1 +CN(C)c1nnc(S(=O)(=O)Cc2nc(-c3ccco3)no2)s1 +Cc1cccc(C(=O)N2CC(c3nc(-c4cccnc4)no3)C2)c1 +COc1ccc(CCCNC(=O)N(C)Cc2ccccn2)cc1 +O=S(=O)(NC1CCc2c(Cl)cccc21)c1cccnc1 +COc1cccc(C(=O)Nc2cc(C)nc3ccc(F)cc23)c1 +C=CCC1(CO)CCCN(C(=O)Cn2nc(C)c(CC)c2C)C1 +O=C(Nc1ccccc1OCCc1ccccc1)c1ccccn1 +Cc1ccc(NC(=O)C2CC=CCC2)cc1-n1cnnn1 +O=C1CN(Cc2c[nH]nc2-c2cccnc2)CCN1CC1CCCC1 +Cc1cc(C)n2nc(CC(=O)N(C)C(C)C)nc2n1 +Cc1occc1-c1nnc(SCc2ccc(F)cc2)o1 +CCn1c(C)cc(C(=O)Nc2nc(CN3CCOCC3)cs2)c1C +CCC(C#Cc1ccccc1)OC(=O)C12CCC(C)(C(=O)O1)C2(C)C +CC(=O)Nc1ccc(C(=O)CNc2cc(C)cc(C)c2)cc1 +COc1ccc(O)c(C2CC(=O)Nc3cc(O)c(C)cc32)c1 +O=C(NCCC1CC2CCC1C2)c1ccccc1N1CCOCC1 +Cn1ccc(C(=O)CSc2nnnn2-c2cccc(F)c2)c1 +CC(=O)Oc1ccccc1C(=O)Nc1ccc(F)cc1F +COc1cc(C#N)ccc1OC(=O)COc1c(C)cccc1C +COc1ccccc1NC(=O)CCC(=O)c1cc(C)sc1C +CC(OC(=O)CCc1cnn(C)c1)c1ccccc1C(F)(F)F +CCC(C)Nc1cc(OC)nc(C2CCCO2)n1 +CC(OCc1ccccc1)C(=O)NCc1cscn1 +CC1(c2ccccc2)CCC(=O)N(CC2(Cn3cccn3)CC2)C1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)NCCCC(C)C +O=C(CCC(=O)OCC1CCCCC1)Nc1nccs1 +CN(CC(=O)N(CCC#N)Cc1ccco1)c1ccc(C#N)cn1 +Cc1cccc(OCC(=O)Nc2ccc3c(c2)OCC(=O)N3)c1 +O=C(c1ccccc1)c1cc(S(=O)(=O)N2CCOCC2)cs1 +COc1ccc(OC(C)C(=O)Nc2c(F)cccc2F)cc1 +O=C(Nc1c[nH]cc(Br)c1=O)c1ccc2c(c1)CCO2 +Nc1ccc2c(C(=O)Nc3c(F)cccc3F)nccc2c1 +O=S(=O)(NCc1ccc2c(c1)OCCO2)c1ccccc1F +Cc1ncc(CNc2cc(Br)ccc2N(C)C)s1 +N#CCn1c(-c2cccc(F)c2)nc2cccnc21 +CS(=O)(=O)NCC12COCC1CN(C(=O)Cc1cccs1)C2 +Cn1nc(C(=O)NCC2CCN(S(C)(=O)=O)CC2)ccc1=O +O=S(=O)(Nc1cccc(OCc2ccncc2)c1)c1cccs1 +Cc1ccnc(NCCc2nc(Cc3ccccc3)no2)n1 +CC(=O)c1ccc2c(c1)CCN(C(=O)OC(C)(C)C)C2 +C#CCOCC1CCCN(C(=O)c2cccc(C#N)c2)C1 +CCC1(CC)C(NC(=O)c2cn(C)nc2C(C)(C)C)CC1OC +COCC(=O)NC(CC(=O)OC)c1ccc(Br)cc1 +COc1ccc(C(=O)Nc2ccc(NC(C)=O)cc2)nn1 +O=c1oc2ccccc2n1Cc1cn(CCC2=CCCCC2)nn1 +Cc1cc(C)n2nc(N)c(Cc3ccccc3)c2n1 +Cc1nn(C)cc1C1CC(O)=Nc2c1c(=O)[nH]n2C1CCCCCC1 +Cc1cccnc1NC(=O)CSc1ccc(F)cc1F +CCOC(=O)NC1CCN(C(=O)CNC(=O)OC)CC1 +N#CCCn1c(CO)cnc1SCc1ccc(F)cc1F +CC(Sc1nncn1C(C)C)C(=O)Nc1ccccc1C(C)C +CC(CNC(=O)N1CCNC(=O)CC1)Cc1cccs1 +O=C1CCC(NC(=O)c2cc3ccccc3oc2=O)CN1 +CCC1(CC)Oc2cccc(N)c2N(CC(=O)OC(C)C)C1=O +COCc1nnc(NC(=O)c2nc(C)sc2CC(C)C)s1 +CC(C)CCc1nnc(NCc2cccc(C#N)c2)o1 +CC1c2ccsc2CCN1c1ncnc2c1cnn2CCC#N +Cn1ccnc1-c1ccc(F)c(-c2cc(N)[nH]n2)c1 +COc1cc(C(=O)NC(C)c2ccc(C)o2)ccc1OCC(N)=O +CN(C)C(=O)c1ccc(CN2CCOC(c3ccc(F)c(F)c3)C2)[nH]1 +CC(=O)Nc1cccc(NC(=O)CCc2ccccc2Cl)c1 +CCCc1cc(C(=O)NCCCn2ccc3ccccc32)[nH]n1 +O=C(COc1ccccc1CO)NCc1ccccc1 +Cc1ccc(Cn2nccc2NC(=O)Cn2c(C)c(C)sc2=O)o1 +CC(c1ccco1)N(C)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +CCOc1ccc(OC(C)C#N)c(Br)c1 +Cc1ccc(C)c(OC(=O)Cc2c(C)nc3c(c2C)c(=O)[nH]n3C)c1 +Cc1cnc(C(=O)Nc2cc(C)nn2CCC#N)cn1 +COC(=O)CC1CN(Cc2cnc(C)n2-c2ccccc2)CCO1 +CCOc1ccc(SCC(=O)N(C)Cc2ccc(C)o2)cc1 +Cc1ccccc1N1CCCN(C(=O)c2cnn3ccccc23)CC1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2cccc(C(N)=O)c2)cc1 +CCOC(=O)c1sc2ncnc(OC)c2c1C +Cc1cccc(C(=O)N2CCN(c3ccccc3F)CC2)c1 +NC(=O)c1cccc(CNC(=O)c2cccc(-n3cccc3)c2)c1 +COCCC1NCCc2cc(O)c(OC(F)F)cc21 +COC(=O)C1(NC(=O)C2COc3ccc(F)cc3C2)CCCCC1 +COc1ccc(C(=O)c2ccsc2)c(OC)c1OC +Cc1c(Cl)cccc1N1CCN(S(=O)(=O)N(C)C)CC1 +COC(=O)c1ccc(NC(=O)c2cnc3onc(C(C)C)c3c2)s1 +CC(NC(=O)c1ccc2ccccc2n1)c1nnc2ccccn12 +CC(=O)c1c(C)[nH]c(C(=O)NCC(C)c2ccccc2)c1C +COc1cccc2ncn(CC(OC)c3cccs3)c(=O)c12 +COC(=O)c1cc(CN2CCOC3(CCC3)C2)c[nH]1 +C=CCOCc1nnn2c1CN(C(=O)c1ccc[nH]1)CC2 +CC(=O)c1ccc(NC(=O)CNC(=O)Cc2cccc(F)c2)cc1C +COC(=O)C1CC(O)CN1Cc1cc(Cl)cc(Cl)c1 +Cc1ccc(NC(=O)c2ccoc2)cc1NC(=O)c1ccncc1 +Cc1csc(CNC(=O)CCc2cccs2)n1 +Cc1c(NC(=O)N2CCCC(C)C2)cccc1C(=O)N1CCCC1 +Cc1n[nH]c(C)c1NC(=O)Nc1ccn(-c2ccccc2)n1 +O=C(Cc1cn2ccccc2n1)Nc1nc2ccc(F)cc2s1 +CC(Cc1ccc(O)cc1)N(C)C(=O)Cn1ccnn1 +Cc1cc(Nc2ccc(C)c(Cl)c2)n2nnnc2n1 +CC(C)S(=O)(=O)c1ccccc1C(=O)N(C)C1CCCCCC1 +CCOC(=O)c1[nH]c2sc3c(c2c1NC(C)=O)CCCC3 +CCOC(=O)c1cnn(-c2ccc(F)c(Cl)c2)c1N +Cc1ccc(-c2nnco2)cc1NC(=O)CNc1ccc(C#N)cc1 +COc1ccc(Cl)cc1S(=O)(=O)N1CCCCC1C +COc1ccc(C2(O)CN(C(=O)N(C)C)C2)cc1 +Cc1ccc(S(=O)(=O)CC(=O)NCC2CCCCC2)cc1C +Cc1cc2c(=O)n(Cc3coc(-c4cccs4)n3)cnc2s1 +O=C1Cn2c(nc3ccccc3c2=O)CN1Cc1ccc2c(c1)OCO2 +COC(=O)c1nnn(-c2ccc(Cl)cc2C)c1N +C=CCOC(=O)N1CCN(C(=O)OCC=C)CC1 +O=C(C1CC(=O)N(C2CC2)C1)N1CCN(Cc2cccs2)CC1 +CCn1c2ccccc2c2nnc(SC3CC(C)OC3=O)nc21 +Cc1cc(NC(=O)c2ccc(COc3ccccc3C)o2)no1 +O=C1CCC(C(=O)NCCCc2nc3ccccc3s2)N1 +CCn1ccnc1SCC(=O)c1cccc(OC(F)F)c1 +Cc1cccc(-n2nnc(C(=O)Nc3ccccc3F)c2C)c1 +COCC(O)CN(C)C(=O)NCc1ccc2c(c1)OCCO2 +COc1ccc(OC)c(CCC(=O)n2nc(C)cc2C)c1 +COc1ccc(CCNC(=O)Oc2ccc3c(c2)ncn3C)cc1 +CCCOC(=O)C(CC)n1c(C)ccc(C#N)c1=O +Nc1ccccc1Cc1nccn1Cc1ccccc1F +Cc1noc(C)c1C(C)NC(=O)CCc1cnn(-c2ccccc2)c1 +CCC(C)Oc1ccc(NC(=O)Cn2ccc(=O)n(C)c2=O)cc1 +CC(C)Cn1cc(C(=O)N2CC(C)OC(C)C2)c2ccccc21 +O=S1(=O)CCCCN1c1ccc(Br)cc1 +Cc1cc(NC(=O)NCC(C)C)n(Cc2ccccc2)n1 +OC(CN1CCc2ccccc21)c1ccc2c(c1)CCC2 +CC1(C)C2CCC1(C)C(NC(=O)N1CCC(C(=O)NC3CC3)CC1)C2 +CC1(c2ccccc2)CCC(=O)N(CCOCCO)C1 +COc1ccc2c(C(=O)NCCCO)cc(=O)oc2c1 +CN(Cc1nc2ccccc2o1)C(=O)CCn1cccn1 +CC(=O)c1cccc(OC(=O)c2ccc(N3CCNC3=O)cc2)c1 +Cc1ccc(NC(=O)C2CC(=O)N(CCC(C)C)C2)cc1 +O=C1CCc2ccc(C(=O)NCc3cccs3)nc2N1 +O=C(CCn1cncn1)N1CCN(Cc2ccccc2)c2ccccc21 +CSc1ccc(C(O)CNC(=O)Cc2ccsc2)cc1 +CCCNC(=O)CCNC(=O)Nc1cccc(C(C)C)c1 +Cc1nc(C(=O)Nc2ccc(Cl)c(Cl)c2)co1 +Cc1ccc(F)cc1C(=O)Nc1cccc(C(=O)N2CCOCC2)c1 +COCC(=O)N(C)Cc1nc(NC2CC2)ncc1-c1cc(C)no1 +Cc1ccn2cc(C(=O)N(C)Cc3nc4ccccc4c(=O)[nH]3)nc2c1 +CC(C)CNC(=O)CN1C(=O)COc2cc(N)ccc21 +CCC(CC)N(C)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +N#Cc1cc(S(N)(=O)=O)ccc1N1CCc2ccccc2CC1 +Cc1c(C(=O)NCCCN2CCCC2=O)oc2c1-c1[nH]ncc1CC2 +CC(NC(=O)COc1cccc(C(N)=O)c1)c1nnc2ccccn12 +COCCNC(=O)C1CCN(S(C)(=O)=O)CC1 +O=C1CC(C(=O)N2CCCC3(CCCCCC3)C2)CCN1 +O=C(CCn1cncn1)NCc1ccsc1-n1cccc1 +NC(=O)OCCNC(=O)Cc1cc(F)ccc1Br +CCc1ccc(CNC(=O)Cn2nc(C)nc2C)s1 +O=C(C1CC1)N(CCc1ccccc1)C1CCOC1 +COCc1ccc(C(=O)NC2CCC(O)CC2)cc1 +CCc1ccc(CN2CCc3c(CNS(C)(=O)=O)cncc3C2)o1 +O=C(NCCO)c1ccccc1CSc1nc2ccccc2[nH]1 +Cc1cc(=O)c(C(=O)N(C)Cc2ccc(O)cc2)nn1-c1ccccc1 +CCN(CC)S(=O)(=O)NC(c1ccc(F)cc1)c1nccn1C +Cc1ccc(-c2noc(CN3CCn4c(C)nnc4C3)n2)cc1F +Nc1n[nH]cc1S(=O)(=O)NCCc1ccccc1 +Cc1ccc2[nH]c3c(=O)n(CC(=O)NCc4cccnc4)cnc3c2c1 +O=C1NCC(C(=O)NC2(c3ccc(Cl)cc3)CCC2)N1 +COC(=O)NCC(=O)Nc1ccc(OC(F)F)c(F)c1 +C=CCCCN(C)C(=O)c1ccc(=O)n(CCC)n1 +CC(=O)Nc1cc(C(=O)NC2(C)Cc3ccccc3C2)ccc1C +CCOC(=O)COC(=O)c1ccc(-c2nc(C)cs2)cc1 +CNc1ncc(-c2ncnn2-c2ccc(F)cc2)cn1 +Cc1nc(C(O)c2ccc(O)cc2)sc1CCO +CCOCc1ccccc1NC(=O)NCc1ccccc1 +Cc1ccc(C(=O)OCc2nc3ccccc3c(=O)[nH]2)n1C +CC(=O)c1ccc(CNC(=O)c2cc(C#N)cn2C)nc1C +Cc1cccc(NC(=O)NCC(C)(O)c2cccs2)c1 +COc1ccc(S(=O)(=O)N2CCN(c3cnccn3)CC2)cc1C +O=C(c1ncn2c1nnc1c3ccccc3ccc12)N1CCOCC1 +CCc1cc(NCc2cccc(C)c2)n2ncnc2n1 +O=C(Nc1ccc(-n2cncn2)c(F)c1)N1CCc2ccccc2C1 +c1cc(NCC2CC2)nc(C2COCCN2Cc2ccoc2)n1 +CCCCc1cc(NC(=O)CNc2ccc(C#N)cc2)[nH]n1 +COc1ccc(NC(=O)C(C#N)Cc2ccco2)cc1 +COCCN1C(=O)c2[nH]nc(-c3ccccc3)c2C1c1ccc(C)cc1 +Cc1onc(-c2ccncn2)c1C(=O)Nc1ccc(OC(C)C)cc1 +Cc1cccc(CNC(=O)c2cnn3c4c(cnc23)CC(C)CC4)c1 +CCCc1nc(C)c(COc2cccc(N)c2)s1 +CCOc1ccc(C(=O)NCC(OC)c2ccsc2)cc1 +COc1cccc(-n2nnnc2S(C)(=O)=O)c1 +COc1ccc(-n2cc(CNC(=O)c3ccc4nncn4c3)nn2)cc1 +Nc1cn2nc(-c3ccc(F)c(Cl)c3)sc2n1 +CC(C)CC(C)S(=O)(=O)NCc1cccc(-c2nc[nH]n2)c1 +Cc1cc(Br)c(NC(=O)NCc2ccncc2)cc1C +CCOC(=O)N1CCC(NS(=O)(=O)c2ccc(F)c(F)c2)CC1 +CNC(=O)c1cccc(S(=O)(=O)N2CC(C)CC(C)C2)c1 +CCOC1CCN(Cc2ccc(OC)cc2)C1Cc1cnn(C)c1 +COC(=O)c1ccccc1NC(=O)c1cc(C)on1 +O=C(CSc1ccccc1)NCC1CCCO1 +Cc1nc(C(N)=O)c2[nH]c(=O)n(-c3ccccc3C(F)(F)F)c2n1 +COCCNC(=O)c1ccccc1NC(=O)C1CCC1 +Cc1nnsc1-c1nnc2sc(-c3csnn3)nn12 +CCCn1nc(-c2ccc(Cl)cc2)cc(C#N)c1=O +COC(=O)C(Cc1ccc(O)c(OC)c1)NC(=O)c1ccccc1 +CCOC1CCCN(C(=O)Nc2cccc(OC(F)F)c2C)C1 +Cc1ccc(C(=O)NCCOc2cccc(F)c2)cn1 +Cc1ccc(CNCc2cc(C#N)ccc2F)cn1 +Cc1ccc(C(=O)NCCCNc2ncccn2)cc1 +NC(c1cccnc1)c1nc2ccccc2n1Cc1ccccc1 +CCC(C)NC(=O)C1(c2ccc(NS(C)(=O)=O)cc2)CC1 +Cc1ccc(N2CC(C(=O)N3CCOCC3)CC2=O)c(C)c1 +Cc1ccc(-n2nnnc2SCC(=O)OC(C)(C)C)cc1 +O=C(Cc1nnc2cc(-c3nc(C4CC4)no3)ccn12)NC1CC1 +CCCN(CCC#N)C(=O)Nc1cccc2ccccc12 +CN(C)c1nc(N)nc(CN2CCN(c3nccs3)CC2)n1 +Cc1cccc2c1CCN2C(=O)Cn1c(C)csc1=O +CSc1nsc(SCC(=O)c2cccs2)n1 +CCN(CC(F)(F)F)C(=O)c1cc(C)sc1C +CCNS(=O)(=O)c1ccc(C)c(C(=O)NC2CCCCC2C)c1 +O=C(CCNC(=O)c1ccc(F)cc1)Nc1ccc(F)cc1 +Cc1nc(NC2CCCC2)sc1C(=O)NCc1ccncc1 +CNC(=O)CSc1nnc(-c2ccc(Cl)cc2Cl)n1C +O=C(Nc1ccccc1)c1csc(Nc2cccnc2)n1 +CC(NC(=O)NC(C)c1cccs1)c1ccc2c(c1)OCCO2 +Cn1c(=O)n(C2CCN(C(=O)c3ccccn3)CC2)c2ncncc21 +C=CCS(=O)(=O)N1CCOC(Cc2cccc(OC)c2)C1 +COC(C)(C)c1noc(CCC(=O)Nc2nccs2)n1 +O=c1ccc(-c2ccc(Cl)cc2)nn1Cc1ccncc1 +Cc1noc(C)c1CCCNC(=O)N1CC(C)CCC1C +CC1Cc2ccccc2N1CCNC(=O)c1cn(C)nc1C(C)(C)C +COC(=O)c1ccc(CSc2nnc(C)n2-c2cccc(C)c2)o1 +CC1CN(C(C)C(=O)c2ccccc2)c2c(N)cccc2O1 +CC(C)CNC(=O)Cn1c(=O)ccc2cc(N)ccc21 +Cc1nocc1C(=O)N1CCC2(CCC(=O)N2CC2CC2)CC1 +CCOc1ccc(S(=O)(=O)N2CCN(CC)CC2)cc1 +Nc1ccc(F)c2ccnc(C(=O)NCc3ccncc3)c12 +N#Cc1cnn2c(C(F)(F)F)cc(-c3ccncc3)nc12 +CCC1C(=O)NCCN1C(=O)c1ccc(OC(C)C)nc1 +CC1CCN(S(=O)(=O)c2cc(Cl)ccc2N)C(C)C1 +Cc1nc(-c2ccc(NC(=O)Nc3cnn(C)c3)cc2)cs1 +COc1cc(C#N)ccc1OC(C)C(=O)Nc1cc(C)ccc1C +Cc1cnn(Cc2ccc(Br)cc2)c1N +O=C1CN(C(=O)NCC2CCCO2)CN1Cc1ccccc1 +CCCCn1nc(C(=O)N2CCN(C3CCOC3)CC2)ccc1=O +Cc1cc2c(cc1F)CCNC2c1c(C)ncnc1C +CCCCNC(=O)c1ccc(S(=O)(=O)N2CCOCC2)cc1 +CC(=O)c1ccc(NC(=O)N2CCCC(N3CCNC3=O)C2)cc1 +Cc1[nH]c2ccc(OCC(C)C)cc2c(=O)c1CC#N +CC1(C)C(NC(=O)c2cccc(C#N)c2)C2CCOC21 +Cn1c(=O)c2sccc2n(CC(=O)NCCc2ccccc2)c1=O +CC(C)(CO)n1c(CC(F)(F)F)nc2ccc(F)cc21 +CC(C)c1nc(C(C)NC(=O)CC2CCCC2)cs1 +O=C(c1ccco1)c1ccc(CNC(=O)C2CCC2)s1 +CSc1ccccc1C(=O)Nc1cc(N2CCC(C)CC2)ncn1 +CCCC1CCCN(C(=O)NCc2ncn(C)n2)C1 +CCn1ccc2cc(NC(=O)c3ccc(S(C)(=O)=O)o3)ccc21 +CC(=O)N1CCC2(C1)CN(S(=O)(=O)c1ccccc1)C2 +CC(C)Nc1cc(N2CCCS2(=O)=O)ccc1F +C#CCNC(=O)N(Cc1ccc(C)s1)C(C)C +COCCN1CCN(C(=O)c2cnc(NC(C)C)nc2)CC1 +Cc1csc(CNC(=O)CCSc2nnnn2C)n1 +COCCC1(CO)CCCN(C(=O)CCc2cnn(C)c2)C1 +O=C(c1ccccc1Cl)N1Cc2cncnc2C1 +O=C(Cc1noc2ccccc12)Nc1c(F)cccc1F +CC(=O)Nc1cccc(NCCOc2ccc(C)c(C)c2)c1 +COC(=O)c1ccc(NCc2nnnn2-c2ccccc2)cc1F +CCS(=O)(=O)N1CCN(CCOC)C(=O)C1 +CCCN(CC(=O)N(C)C)C(=O)c1sc2ccccc2c1COC +CCc1nc(CNc2ccc3c(c2)NC(=O)CS3)cs1 +Cc1sc2ncnc(NCC(c3cccs3)N(C)C)c2c1C +Cc1ccc(C)c(CC2Oc3cc(O)ccc3N(C)C2=O)c1 +CCOc1ccc(C(=O)Nc2ccccc2C(=O)N(C)C)cc1 +Cc1ccc(C(=O)OCC(=O)NC(C)c2ccccc2)s1 +COc1ccccc1NC(=O)C1CCCN(C(=O)N2CCCC2)C1 +CSc1cccc(-n2nnc(C#N)c2C2CCCO2)c1 +COCC(C)N(C)c1cc(N)cc(S(N)(=O)=O)c1 +COC(=O)c1occc1CSc1nnc(C2CC2)n1C +O=C(c1cc(F)ccc1Cl)N1CCc2c([nH]c3ccnn3c2=O)C1 +Nc1ccc2nc(C(O)c3ccccc3)sc2c1 +CC(=O)Nc1ccc(F)c(NCc2nnc(C(C)(C)C)o2)c1 +OCCCNc1nc(-c2ccccc2)nc2ccccc12 +CCOCC1CCN(C(=O)c2c[nH]nc2-c2ccccc2Cl)CC1 +COc1cc(CNC(=O)Cn2c(=O)oc3ccccc32)ccn1 +O=C(CCNC(=O)c1n[nH]c2ccccc12)NCCc1cccs1 +CCS(=O)(=O)NCC1(COC)CC(O)C(O)C1 +C=CCOc1cc(Br)c(CO)cc1OCC +COCc1nn(Cc2nnc(-c3cccc(C)c3)o2)c(=O)o1 +COc1cc2c(cc1O)C(c1cnccn1)NCC2 +CCC(NC(=O)c1cc(CN2CCOCC2)on1)c1ccc(O)cc1 +Cc1ccc(C(=O)N2CCCC2c2noc(C(C)C)n2)c(=O)[nH]1 +Cc1ccc(C(NC(=O)CS(=O)(=O)N(C)C)c2ccccc2)cc1 +CC(C#N)CNC(=O)CCN1C(=O)COc2ccccc21 +O=C(NCCC(O)c1ccco1)c1cc(-c2ccccc2)on1 +CC(C)c1nc2c(c(=O)[nH]1)CCN(Cc1ccccc1F)CC2 +Cc1ccc(CC(=O)NCCCN(C)S(C)(=O)=O)s1 +Cc1ccc2c(c1)c(=O)c(C)c1n2C(=O)c2ccccc2-1 +Cc1ccc(CNC(=O)c2nnc(-c3ccccc3)o2)cc1 +Cc1ccc(CC(=O)OCC(=O)Nc2c(C)cc(C)cc2C)cc1 +CCc1cccc(OCc2nn3c(CO)c(C)nc3s2)c1 +C=C(C)CN(CC)S(=O)(=O)N1CC(C)OC(C)C1 +CCOC(=O)c1c(NCc2ccco2)c2ccccc2[nH]c1=O +NC(=O)Cn1nc(-c2ccc(N)cc2)c2c1CCCC2=O +CC1=CCC2CN(C(=O)CCN3Cc4ccccc4C3=O)CC2C1 +O=C(CCc1cn2cccnc2n1)NCC(=O)NCC1CCCCC1 +CC1CN(C2CCN(C(=O)c3ccco3)CC2)CC(C)O1 +C=CCN(CC=C)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +COC(=O)c1cccc(NC(=O)N2CC(C)OC(C)C2)c1 +CCc1ccccc1NC(=O)Cn1cc(Cl)c(=O)[nH]c1=O +O=C(NCc1ccccn1)c1ccc(Cl)cc1-n1cnnn1 +COc1cc2c(cc1OC)C1CC(=O)CC(=O)N1CC2 +CC1CN(CC2CN(C(=O)Cn3cncn3)CC2CO)CC(C)O1 +CC1COCC(C)N1C(=O)c1cc(F)cc2[nH]cnc12 +Cc1cc(NC(=O)NCCC2CCCCO2)c[nH]c1=O +Cc1cc(NC(=O)C2CC2)sc1C(=O)Nc1nnc(C2CC2)s1 +CC(C)N(CC(N)=O)S(=O)(=O)c1ccc(F)cc1 +CC(NC(=O)c1cccc(-c2nnnn2C(C)C)c1)c1ccccc1 +Cc1nnc(SCC(=O)Nc2nncs2)n1-c1ccccc1 +C#CCNC(=O)c1ccccc1NS(=O)(=O)c1ccc(Cl)cc1 +Oc1cc2c(cc1Br)CCNC2C1CC1 +Cc1noc(C(C)S(=O)(=O)c2cc(F)ccc2F)n1 +Cc1ccc(C#N)c(NC(=O)CCc2ccccc2)n1 +CC1(C(=O)NCCc2nccn2C(F)F)CC1(Cl)Cl +Fc1cccc2ncnc(NCc3cn4cccnc4n3)c12 +COc1ccccc1CCN(C)C(C)c1nc(-c2cccnc2)no1 +CCOc1cccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c1 +Cc1cc(N2CCCC2c2cccc(CCC(=O)N(C)C)n2)ncn1 +O=C(CCc1nnc(-c2ccccc2)o1)Nc1ccncc1 +Cc1ccc(C(=O)C(C)OC(=O)c2n[nH]c(=O)c3ccccc23)cc1 +CC(=O)Nc1ccc2c(c1)nc(C(=O)NCC(C)C)n2C +CC1(C)CN(C(=O)c2cccc(-n3cccn3)n2)CCO1 +COCC(NC(=O)c1ccc(F)cc1OC(F)F)C(N)=O +Nc1nccnc1C(=O)Nc1cccc(OC2CCCC2)c1 +CC(=O)c1cc(Br)c(F)c(F)c1F +O=C(C1CCCN1C(=O)C1CC1)N1CCC(c2cccc(F)c2)C1 +CC1CCCN(CC(=O)N(C)C2CC2)c2ccccc21 +c1ccc(-n2nnnc2NCCc2c[nH]c3ccccc23)cc1 +COc1ccccc1C1CC1NC(=O)c1ccc2[nH]cnc2c1 +CC(NS(=O)(=O)c1ccc2c(c1)CCO2)c1ccccn1 +CCC(=O)Nc1nc2cc(OC)c(OC)cc2s1 +Cc1noc(C(C)OC(=O)C2CCN(C(=O)c3ccoc3)CC2)n1 +CN(CCC#N)C(=O)CSc1nnc(-c2ccco2)n1N +Cc1cccc(NC(=O)c2ccc(CO)cc2)c1C +O=C(Cn1nc(-c2cccs2)ccc1=O)N1CCCCCC1 +O=C(Cn1nnc2ccccc2c1=O)Nc1nnc(C2CC2)s1 +CCc1c(-c2cc(OC)ccc2OC)nc2ccc(N)cn12 +Cc1cnccc1C1NCCc2ccc(O)c(Cl)c21 +CCN(CC)C(=O)Nc1ccc(C(C)N2CCOCC2)cc1 +COC(=O)c1ccccc1NC(=O)c1ccc2nccnc2c1 +Cc1ccn2ncc(C(=O)N3CCC(Nc4cccnn4)CC3)c2n1 +Cc1cc(C)c(C(=O)COC(=O)CCn2c(C)csc2=O)c(C)c1 +Cn1cccc1C1CCCCCN1C(=O)c1ccc(-n2cnnc2)cc1 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1nc2ccccc2c(=O)[nH]1 +N#CC(c1ccccc1F)N1CCOC(c2ccccc2)C1 +COC(=O)c1ccc(-c2cncc(OC)c2)cc1F +COc1ccccc1COC(=O)c1cccc(C#N)c1 +CSc1ncc(C(=O)NCc2nc(-c3ccccc3)no2)cn1 +CN(Cc1cccc(-n2cccn2)c1)C(=O)c1cnc2ccccc2c1 +CC(NCC(=O)Nc1ccccc1C(N)=O)c1ccccc1 +Cc1nc(SCC(=O)c2cnn(C)c2)oc1C +CC1CC1CNC(=O)CNC(=O)NC1CCCCC1 +O=C(c1cnn(Cc2ccccc2)c1)N1CCCC1 +CC(C)(C)n1cc(C(=O)Oc2cccc(C(N)=O)c2)cn1 +COC(=O)c1ccc(C(=O)NCC(OC)c2ccccc2C)cc1 +CCc1ccc(C(=O)N2CCN(c3ncccn3)CC2)s1 +Cc1noc2nc(C(C)C)cc(C(=O)Nc3ccc(N(C)C)nc3)c12 +CC(O)CNC(=O)c1cc(=O)c2cc(N)ccc2o1 +N#CCCn1ccc(=O)c2cc(Br)ccc21 +CN(C)c1ncnc(-n2cnc3ccccc32)c1N +COC(=O)C(CC(C)C)NC(=O)c1cc(-c2ccccc2)[nH]n1 +COc1ccc(Cn2c(C(F)(F)F)nc3ccc(N)cc3c2=O)cc1 +N#CC(CC(=O)Nc1ccccc1)c1c[nH]c2ccccc12 +Cc1cc(C(O)C(=O)Nc2cccc(Cl)c2)ccc1F +CC(C)NC(=O)CNC(=O)c1n[nH]c2cc(Cl)ccc12 +CC(C)(C)NC(=O)c1ccc(Br)cc1 +Cc1noc(C2CCOC3CCN(c4ncc(F)cn4)CC32)n1 +Cc1cc(COc2ccccc2)oc1C(=O)N1CNC(=O)C1 +COCCCn1c2c(cc(CO)c1=O)CCCC2 +Cc1cnc(C(=O)N(C)Cc2nc3ccsc3c(=O)[nH]2)cn1 +O=C(Cn1cc(Br)ccc1=O)NCC1CCCCC1 +CCOc1cc(F)ccc1NCc1cnc(C2CC2)s1 +Cc1cc(C)n(CC(C)CNC(=O)c2ccc(F)cc2)n1 +COc1cc(CO)cc(N)c1OCC(O)c1ccc2c(c1)OCO2 +O=C(Nc1cnc(-c2ccccc2)nc1)C1(c2ccccc2)CC1 +O=C(NCCNc1nnnn1-c1ccccc1)Nc1cccc(F)c1 +Cc1cnc(NC(=O)c2ccc3[nH]c(=O)[nH]c3c2)s1 +CN(C(=O)CSc1c(N)cccc1Cl)C1CC1 +CCc1nnc(-c2ccc(S(=O)(=O)Nc3cccc(OC)c3)o2)o1 +COCCCNC(=O)C1CC(=O)N(c2ccccc2C)C1 +CC(=O)N1CCC(C(=O)NCc2cccs2)CC1 +O=C(Cn1ccccc1=O)N1CCN(Cc2cccnc2)CC1 +CCN(CCNC(=O)N1CCC2(CC1)OCCO2)c1ccccc1C +O=C(NCC1CC1)C1CCCN(c2ccnc(-c3ccccc3)n2)C1 +CCc1ccc(NC(=O)c2nc3nccc(C)n3n2)cc1 +NS(=O)(=O)c1ccc(C(=O)NCCc2ccccc2)o1 +CCCCC(=O)N1CCN(S(=O)(=O)Cc2ccccc2)CC1 +CCC(=O)NCC(=O)NC1CCN(c2c(F)cccc2F)C1 +CCOc1ccc(F)c(C(=O)N2CCCC(C(=O)NC)C2)c1F +CC(O)c1cccc(NCc2ccc(F)c(F)c2)c1 +CC1NCc2ccccc2C1NC(=O)C1CCCO1 +COc1cc(CN2CCC3(C2)OCCO3)c(Br)cc1O +CSc1nc2n(n1)C(c1ccccc1Cl)C1C(=O)CCCC1=N2 +Cc1cccc2c1CCNC2Cc1ccc(O)cc1 +CCC1Oc2cccc(N)c2N(CC(=O)NCCOC)C1=O +CC1(C)CN(C(=O)NCC2CCOC2)CCN1Cc1ccccc1 +Cc1ccc2c(c1)c(=O)c(C(=O)NCCc1cccs1)nn2C +COc1ccc(C)cc1-c1ncncc1Br +CCC(=O)c1cccc(S(=O)(=O)N(C)C(CC)c2ccncc2)c1 +CCNS(=O)(=O)c1ccc(NC(=O)c2cccc(OC)c2)cc1 +O=C(C1C2CCC(C2)N1C(=O)c1ccco1)N1CCCC1 +Nc1cnc2nc(CCOc3ccccc3)oc2c1 +CCOC(=O)COc1cc(Br)c(CO)cc1OC +COC(=O)c1cc(CNC(=O)c2cc(=O)[nH]c3ccccc23)oc1C +FC(F)(F)Oc1ccccc1-c1nnc(-c2ccncc2)o1 +Cc1nc(CC(=O)Nc2cc(Cl)ccc2N(C)C)cs1 +O=C(Cc1ccc(F)cc1)Nc1ccc(-c2ncc[nH]2)cc1 +COC(CCc1ccc2c(c1)OCCCO2)(OC)OC +CCS(=O)(=O)N1CCN(C(=O)c2cc3ccccc3cc2N)CC1 +CCOCC(C)NC(=O)c1ccc(Br)cn1 +CC(C)(C)OC(=O)N1CCN(CCn2ccccc2=O)CC1 +CCOC(=O)N1CCN(c2ccc(C(C)=O)cc2)CC1 +Cn1cc(CCC(=O)N2CCc3ccccc32)c2ccccc21 +C=CCNC(=O)c1cccc(S(=O)(=O)NCc2ccncc2)c1 +O=C(CCc1ccc(F)cc1)NCCNC(=O)C1CC1 +Cc1ccc2oc(C(=O)c3cc(C(N)=O)co3)cc2n1 +Cn1ccc(NC(=O)CCOc2cccc(F)c2)n1 +CCN(CC)C(=O)CCC(=O)Nc1cccc(N2CCCCC2)c1 +COc1ccc2[nH]c(-c3nc(C)nn3-c3ccccn3)cc2c1 +CCn1nc(C)cc1C(=O)Nc1cc(C)nn1Cc1ccccc1 +Oc1cc(F)c2c(c1)C(c1cncc(F)c1)NCC2 +N#Cc1ccc(-c2noc(CCNC(=O)c3ccsc3)n2)nc1 +Nc1ncccc1OCC(=O)NC1CCCCCC1 +Cc1ccc(CNC(=O)c2ccc3[nH]nnc3c2)cc1 +CC(c1ccccn1)N(C)C(=O)Nc1cccc(F)c1F +Cc1ncc(CNC(=O)Cn2nnc3ccccc3c2=O)s1 +O=C(CCC1CCCC1)Nc1nnc2n1CCCS2 +CCc1nnc(NC(=O)CSc2ccc3c(c2)OCCO3)s1 +COc1ccccc1C(NC(=O)NCc1ccco1)c1nccn1C +Cc1cccc(NC(=O)CCC(=O)Nc2nnc(C(C)C)s2)c1 +CNC(=O)c1cccc(CCNC(=O)NCc2ccc(C)s2)c1 +CCNc1nnc(SCCC(=O)Nc2cccc(C#N)c2)s1 +Cc1ccc(N)cc1N1CCN(C(=O)Cc2cccs2)CC1 +COC(=O)CCSc1nncn1-c1ccccc1C +COc1cc(OC)c2c(CO)cn(CCCO)c2c1 +COC(=O)C(c1ccccc1C)N1CCCC(CC(N)=O)C1 +O=C(NCCc1ccccc1)c1cc(Br)c[nH]1 +Cc1nnc(NC(=O)NCC(O)c2cccc(Cl)c2)s1 +CN(CC1CCCN(C(=O)NC2CC2)C1)C(=O)OC(C)(C)C +O=C(c1ccco1)N1CCCC(C(=O)N2CCc3ccccc32)C1 +O=S(=O)(NCCc1ccco1)c1ccccc1 +O=C(c1ccsc1)N1CCc2cc(Br)ccc21 +OC1(CNC2=NC=NC3=NC=NC32)C2CC3CC(C2)CC1C3 +Nc1nc(COC(=O)c2ccc(O)cc2)nc2ccccc12 +Fc1cc(Br)ccc1CN1CCOC(C2CCCO2)C1 +O=C(NCc1cccnc1)c1ccnc(-c2cccs2)c1 +COc1ccccc1CN(C)C(=O)CS(=O)c1ccc(C)cn1 +COCCc1noc(-c2cn(CCc3ccccc3)nn2)n1 +CSc1nnc2n1-c1sc3c(c1-c1nc(C)nn1-2)C(C)CCC3 +O=C(CCc1nc2ccccc2[nH]1)OC1CCCC1 +CCc1cc(NCC2CC=CCC2)n2ncnc2n1 +O=C1C2C=CC(C=CC2)C1(c1ccccc1)c1ccccc1 +O=C(c1ccc(Cn2nnc(-c3cccs3)n2)cc1)N1CCCC1 +CC(C)(C)NC(=O)CNC(=O)NC1CCSc2ccc(F)cc21 +CCC1c2ccsc2CCN1C(=O)c1ccc(OC)cc1 +Cc1cnc(C(=O)NC(C)c2ccc(F)cc2F)cn1 +CC(c1nnc(-c2cccs2)o1)N1CCc2sccc2C1 +Cc1cnn(CCNc2ccc3nnc(-c4ccccc4)n3n2)c1 +CC(=O)NCC(=O)NCC(=O)Nc1cccc(N(C)C(C)C)c1 +COC(=O)COc1cc(C)nc(-c2ccc(Cl)cc2)n1 +COc1ccc(Cc2nnc(C=Cc3ccccc3OC)o2)cc1 +CC(Oc1ccccc1)C(=O)C(C#N)c1nnc2n1CCCCC2 +CC(Sc1nncs1)C(=O)N(C)CC(N)=O +CC(C)NC(=O)CNC(=O)COC(=O)c1n[nH]c(=O)c2ccccc12 +CCC1CCCCN1S(=O)(=O)c1cc(OC)c(C)cc1OC +CC(NC(=O)CN(C)c1ccc(F)c(F)c1)C1CC1 +Cc1cccc(C2CCCN2C(=O)c2ccnc(-n3ccnc3)c2)c1 +Cc1ccc(OCC(=O)NC(C)c2cccc(S(N)(=O)=O)c2)cc1 +C#CCN1CCN(CC(=O)NCc2ccc(OC)cc2)CC1 +CC(=O)N1CCCC(C(=O)NCCc2noc(-c3ccccc3)n2)C1 +Oc1cccc(CC2NCCc3cc(F)c(F)cc32)c1 +COc1cccc(CNC(=O)c2sccc2C)c1OC +CC(=O)c1cccc(NC(=O)Cn2c(C)ccc(C#N)c2=O)c1 +Cc1cccc(OC2CCN(C(=O)C3CCC3)CC2)n1 +CC(=O)C1CCC2C1(C)CCC1C23CCC2(O)CC(O)CCC12CO3 +CCS(=O)(=O)N1CCCn2c(nnc2Cn2cccn2)C1 +COc1cc(OC)cc(C(=O)NCC(=O)N2CCCCCC2)c1 +CCOC(=O)c1nocc1C(=O)c1ccc(C)cc1 +CC1OCCC1NC(=O)NCCSc1ccccc1F +CC1CCCC(C)N1S(=O)(=O)c1ccc(C#N)cc1 +CC(C)c1cc(C(=O)NCC(O)c2c(F)cccc2F)n[nH]1 +Cc1nn(C)c(C)c1CC(=O)NCCc1ccc(C(F)(F)F)cc1 +O=C(CCC(=O)c1cccs1)NCC1(c2ccc(F)cc2F)CC1 +Cc1nnc(NC(=O)NC(C)c2c(C)nn(C)c2C)s1 +CCN(Cc1noc(CC(C)C)n1)C(=O)Nc1ccc(F)cc1 +CC1CN(C(=O)NCc2ccc(F)cc2)CC1(C)O +CCCCN(C)C(=O)CN1C(=O)CNc2ccccc21 +Cn1nc(CC(C)(C)C)cc1NC(=O)NC1c2ccccc2CC1O +Cc1cc(C(=O)NC2CCCc3nc(-c4ccncc4)ncc32)on1 +CC(C)CC(=O)Nc1ccc2c(c1)CCC(=O)N2CC(C)C +O=C(CC1C(=O)NCCN1C(=O)C1CCC1)OCc1ccccc1 +Cn1cc(C(=O)N2CCC(c3ccccc3)C2)c(C(C)(C)C)n1 +CCCc1nnsc1C(=O)NCC(O)c1ccc(SC)cc1 +CC(C)Oc1ccc(C(=O)Cc2ccncc2)cc1 +Cn1cnc(CNC(=O)NC(c2ccc(Cl)cc2)C2CCCC2)n1 +CN(Cc1ccccc1)c1nc(C#N)c2c(n1)CCC2 +CCCNC(=O)CC1Oc2ccc(Cl)cc2NC1=O +c1cnc(-n2cc(NCc3cc4ccccc4o3)cn2)nc1 +Cc1noc(-c2ccc(SCC(=O)NCc3ccco3)nc2)n1 +CC1CN(C(=O)c2c[nH]nc2-c2ccc(Cl)cc2)CC(C)O1 +Cc1cc(C(=O)NC(C)Cn2ccc(C)n2)c2c(C)noc2n1 +COCC(=O)NCC(O)c1ccc(SC)cc1 +CC(C(=O)Nc1cccc(Cl)c1)S(=O)(=O)c1nccn1C +Cc1cccc2nc(CNC(=O)C34CCC(C)(C(=O)O3)C4(C)C)cn12 +C=CCn1c(SCc2nc(C)no2)nnc1-c1ccco1 +CC(C)Cc1ncc(C(=O)Nc2ccccn2)c(N)n1 +COc1ccccc1NC(=O)C(C)Sc1nnc(C)s1 +Cc1cc(C)n(CCCNC(=O)Nc2cccc3c2C(=O)NC3)n1 +CCNC(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1 +NC(=O)C(NCc1cccc(F)c1)c1ccc(Br)cc1 +Cc1cc(C)c(C(=O)N2CCCC(Cn3cc(C(C)(C)C)nn3)C2)[nH]1 +O=C(NC1CCN(c2nccs2)CC1)c1ccccc1F +Cc1cccc(NC(=O)C2Cc3ccccc3C(=O)O2)c1 +CCCCN(CC)C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +OCCn1c(Cc2ccc(F)cc2)nc2ccccc21 +COc1cccc(S(=O)(=O)NCC#CCN2CCOCC2)c1 +O=S(=O)(Cc1csc(Cc2ccccc2F)n1)c1ccccc1 +CCc1onc(C)c1NC(=O)c1cccc(OCc2cscn2)c1 +Cc1ncsc1CN1CCC2(CC(Oc3ccccn3)CO2)C1 +CCn1cc(CC(=O)N2CCOCC2C2CC2)c2ccccc21 +CC(C)Cc1nc(C(=O)NCCNC(=O)C(C)C)cs1 +C#CCn1c(C(C)NC(=O)c2ccccc2C)nc2ccccc21 +C#CCN1CCN(C(=O)NCC2(CCOCC)CCCC2)CC1 +CC(C)c1nc(NC(=O)c2scnc2C2CC2)n[nH]1 +O=C(c1ccc(-n2ccnc2)cc1)N1CCC(F)(F)CC1 +COc1ccc(-c2cc(N)c(=O)n(C)n2)cc1C(C)C +Cc1cccc(-c2noc(-c3c(C)noc3C)n2)c1 +COc1ccccc1NC(=O)NC(C)c1ccc(-n2cncn2)cc1 +Cn1nc(CN2CCCC2=O)c2c1CN(c1ncccn1)C2 +Cc1ccc(NC(=O)CN(c2ccc(C#N)cc2)S(C)(=O)=O)cc1 +O=C(c1cccs1)N1CCC(S(=O)(=O)c2ccccc2)CC1 +COc1ccc(NC(=O)NCc2ncoc2C)cc1OC(F)F +O=C(NCC(=O)N1CCCC1)Nc1ccn(-c2ncccc2Cl)n1 +Cc1ccc(-c2cnc(CCC(=O)NCc3ccco3)o2)cc1C +O=C(COc1ccc(F)cc1)Nc1cccc(C(=O)NC2CC2)c1 +CCN(C(=O)Cc1c(C)nn(C)c1C)c1nc2ccccc2s1 +CC(C)(NC(=O)c1cccnc1N)c1cccc(Cl)c1 +COC(=O)C1CCN(C(=O)c2ccc(OC)cc2O)CC1 +Cc1ccc(CNC(=O)c2c(-c3ccc(F)cc3)noc2C)cc1 +O=C(Nc1nc(-c2cccc3ccccc23)cs1)c1cnccn1 +NC(=O)Nc1ccc(C(=O)OCc2cc(-c3cccs3)on2)cc1 +CC(C)(O)CNC(=O)Cc1cccc(OCC#N)c1 +Cc1nc(C(F)(F)F)ccc1C(=O)N1CCn2c(C)nnc2C1 +O=C(Cc1csc(-c2cccs2)n1)NCC(F)(F)F +CCn1c(SCc2ccccc2N(C)C)nnc1-c1cnccn1 +CCC(C)Nc1nc(C(C)C)nc(OCC(C)C)c1N +CC(=O)C(C)CSc1nnc(N2CCCC2)n1-c1ccc(C)cc1 +CCCC(=O)Nc1nc2ccc(CC(=O)N3CCCC3)cc2s1 +CCOC(=O)CN(C(=O)c1ccncc1)C(C)C +CN(C(=O)C1CC=CC1)C1CCN(C(=O)OC(C)(C)C)CC1 +COC(=O)c1cc(C(=O)NCc2ccc(Br)cc2)ccn1 +CC1Sc2ccc(C(=O)Nc3nncs3)cc2NC1=O +C#Cc1cccc(NC(=O)c2ccc(Cl)c(N)c2)c1 +CCC1CCC(NC(=O)Nn2cnc3ccccc32)CC1 +CC(=O)NCC1CCCN(C(=O)C2COc3ccc(F)cc3C2)C1 +Cc1nn(C)c2c(NCCN3CCOCC3)nc(C3CC3)nc12 +CN(Cc1ccccc1N1CCCC1)S(=O)(=O)c1cccs1 +CCN(CC)C(=O)CNc1cc(NC(C)=O)ccc1F +Cc1cc(C)cc(NC(=O)NC2CCN(c3ccccc3)C2=O)c1 +CCc1nnc(CNC(=O)c2cnc(N(C)C)nc2C)s1 +COc1ccc(-c2csc(NC(=O)c3ccco3)n2)cc1 +CCc1cc(N2CCC(O)CC2)n2nc3nc(C)cc(C)c3c2n1 +Cc1c(F)ccc2c1C(c1cccc(O)c1)NCC2 +Cc1cccc(OS(=O)(=O)c2ccc(C(N)=O)cc2)c1 +Cc1cc(C)n2cc(CN3CCc4cc(F)ccc4C3)nc2n1 +CCOc1ccccc1CNc1cnn(CC(C)C)c1 +CCOCCN1CCN(c2ccc(C#N)cn2)CC1 +CCc1ccc(OCc2nnc3c(N)cccn23)cc1 +COC(=O)c1c(NC(=O)c2ccnn2C)sc2c1CCCC2 +NC(=O)CCN(c1ccccc1)S(=O)(=O)c1ccccc1 +CCc1ccsc1C(=O)NC1CCSc2ccccc21 +CN(Cc1noc(C2CCC2)n1)C(=O)c1cc2c(s1)CCCC2 +CCCc1noc(CCCC(=O)Nc2nccs2)n1 +Cc1ccccc1C(=O)NC(C(=O)Nc1cccc(C#N)c1)C(C)C +CC(CCO)NC(=O)Nc1cc(C(C)(C)C)sc1C#N +CCCC1CN(C(=O)c2ccc3c(=O)n(C)c(=O)n(C)c3n2)CCO1 +Cc1ccc(C(=O)N2CCC(C(O)c3ccccc3)CC2)c(C)c1 +Cc1nc(CN2CCN(c3ccccc3C#N)CC2)cs1 +Cc1ccc2c(CC(=O)N3CCC(C(N)=O)CC3)coc2c1C +CC(c1ccco1)N(C)C(=O)CCNS(=O)(=O)c1cccnc1 +O=C(CCc1ccccc1)N1CCn2c1nc1ccccc12 +Cc1ncc(CNC(=O)NCC(=O)NC2CC2)s1 +Cn1ncc2c(=O)n(CCOc3cccc(C#N)c3)cnc21 +Cc1ccc(-c2nnc(-c3cccc(N)c3)o2)cc1F +CCc1nn(CC(N)=O)c(=O)c2cc3oc(C)cc3n12 +COc1ccccc1NC(=O)c1cnc2cc[nH]c2c1 +COc1cc(F)c(Cc2ccc(C(C)NC(C)=O)cc2)cc1OC +CC(C)Cn1nc(C(=O)OCC(=O)N(C)C)c2ccccc2c1=O +CC(=O)Nc1ccc(F)c(C(=O)NCC2(c3ccccc3)CCC2)c1 +CCOC(=O)C1CCCN(C(=O)c2ccc(N3CCCC3)nn2)C1 +O=C(Nc1cn[nH]c1)c1cccnc1N1CCCC1 +N#Cc1cc2c(nc1N1CC3C4CCC(O4)C3C1)CCCC2 +CCCn1nc(C(=O)Nc2ccc3[nH]c(C)cc3c2)ccc1=O +COC(=O)C(C)NC1CS(=O)(=O)c2ccccc21 +CCN(C(=O)CC(C#N)C(=O)N1CCCC1)c1ccccc1 +C=CCNC(=O)NC(C)C(OC)c1ccc(Cl)cc1 +Cc1occc(=O)c1OCC(=O)Nc1ccccn1 +Cn1cc(C2CC2C(=O)Nc2ccc(F)c(-n3cccc3)c2)cn1 +CC(Cc1cnccn1)NCc1cc(=O)c2cccc(Cl)c2[nH]1 +CC1CCCCC1NC(=O)CS(=O)(=O)c1ncccc1Cl +CS(=O)(=O)c1cc(C(=O)NCC(=O)NC2CC2)ccc1Cl +O=C1NC(c2cnn(-c3ccc(F)cc3)c2)Nc2cc(Cl)ccc21 +CCOC(=O)Cc1c(C)[nH]c2c1c(=O)n(C)c(=O)n2C +CCOC(=O)C(C)NC(=O)c1cccc(OCC)c1 +c1ccc(Cc2noc(CN3CCc4cncnc4C3)n2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)N1CCCC1CC(C)(C)C +Cc1ccc(NC(=O)NC(C)c2ccc(S(N)(=O)=O)cc2)cc1 +Cc1cccc(C(C)C)c1NC(=O)C(C)Oc1cccc(C#N)c1 +CN(C)C(=O)CSc1n[nH]c(=O)n1-c1ccccc1 +COc1cccc(CNc2ncc(C(N)=O)cc2Cl)c1 +COC(=O)c1cccc2c1CCCN2C(=O)c1cc(C)sc1C +CC(C)NS(=O)(=O)c1ccc(NC(=O)c2cccc(C#N)c2)cc1 +CC(C)(C)C(=O)NCCCNC(=O)c1ccco1 +Cc1nc2ccc(F)cc2c(=O)n1CC(=O)NCCc1nccs1 +COc1c(F)ccc2c1C(c1ccc(O)cc1F)NCC2 +CCOC(=O)C1CCCN(Cc2nc3ccccc3c(=O)[nH]2)C1 +OC(CSc1nc(-c2ccccc2F)n[nH]1)c1ccccc1F +Cc1ccc(C(=O)NCCOc2ccccc2C)s1 +CCN(CC)S(=O)(=O)c1cc(Cl)ccc1Cl +O=C(CC1C=CCC1)NCCNc1ncnc2sccc12 +CNC(=O)Nc1cccc(OCC(=O)N2CCCC2)c1 +Cc1n[nH]c(C)c1-c1nc2c([nH]1)CC(C)(C)CNC2=O +CCCn1nc(C(=O)NCCNC(=O)C(C)C)ccc1=O +CCOc1ccc(SC(C)C(=O)NC2CC2)cc1 +O=C(c1ccccc1)C1CCCN(C(=O)c2ccc(F)cc2F)C1 +O=C(Nc1ccccc1CN1CCc2ccccc21)c1ccncc1F +Cc1cc(=O)n(CC(=O)N2CCCC2)c(N2CCOCC2)n1 +COc1ccccc1CNC(=O)c1cnn2cccnc12 +Cc1ccc(OC(=O)CSc2nnnn2C2CC2)cc1 +CC1(C)OC2C(CO)OC(OCc3ccccc3)C2O1 +O=C(Nc1ccc(F)nc1)N1CCOCC(O)C1 +COc1ccc(C)cc1NC(=O)CCCn1c(C)csc1=O +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NCCCO)CC2)cc1 +COc1ccc(C(O)CNc2ncnc3c2cnn3CCC#N)cc1 +N#Cc1cc2cc3c(cc2nc1SCC(N)=O)OCCO3 +CNC(=O)c1cc(S(=O)(=O)Nc2cccc(C(C)=O)c2)cs1 +Cn1c2c(cc(C(=O)N3CCN4CCNC(=O)C4C3)c1=O)CCCC2 +O=C(CCC1CCCO1)N(Cc1ccc(Cl)cc1)C1CC1 +O=C(COc1ccccc1F)Nc1cc(N2CCOCC2)ncn1 +CCCn1nc(C)cc1NC(=O)Nc1ccc(OC)cc1 +CN1C(=O)Cc2cc(-c3csc(NC4CCCC4)n3)ccc21 +O=C(CCc1ccc(F)c(F)c1)N1CCCc2ncccc21 +O=C(c1cc[nH]n1)N(CCC(F)(F)F)C1CCCCC1 +Cc1cc(C(=O)N(CC2CCOC2)C2CC2)no1 +O=C(CCc1nc2ccccc2c(=O)n1C1CC1)NC1CC1 +CCn1c(SCC(=O)N2CCC(C)CC2)nnc1-c1ccco1 +Cc1ccc(C)c(C(=O)Cn2nc(-c3ccco3)oc2=O)c1 +COc1ccc(-n2nnnc2C(C)(C)Nc2ccc(C)cc2)cc1 +Cn1c(SCc2ccc(F)c(Br)c2)n[nH]c1=O +Cc1ccc2[nH]c(SC(C(=O)N(C)C)c3ccccc3)nc2c1 +CCN(c1ccc(N)c(OC(C)C)n1)C(C)COC +CC(=O)NC(C)C(=O)Nc1ccc2c(c1)OCCO2 +c1cc(OCC2CCCO2)ccc1CN1CCOC(C2CCCO2)C1 +OC1Cc2ccccc2C1Nc1ncccc1C(F)(F)F +O=C(CCCn1cccn1)N1CCN(C2CCCC2O)CC1 +CCCn1nnnc1COc1ccc(C(=O)OC)cc1 +Cc1cc(C)c(-c2cc(CO)nn2CCO)c(C)c1 +CC(C)c1noc(CCC(=O)N2CCC(C(N)=O)c3ccccc32)n1 +Cc1cc(C)n(CCC(=O)NCCNC(=O)c2cccnc2)c(=O)n1 +Cc1cc(CNC(=O)c2c(-c3ccccc3Cl)noc2C)no1 +Cc1c(C(=O)NCCC(=O)N2CCCC2)cccc1-c1ccccn1 +Nc1ccccc1C(=O)N1CCN(c2cccc(Cl)c2)CC1 +Cn1c(CCC(N)=O)nnc1SCC(=O)c1c[nH]c2ccccc12 +COc1cccc(CNC(=O)NCC2(c3ccc(F)cc3)CC2)c1 +Cc1ccc(C)c(OCCCCC(=O)Nc2nncs2)c1 +O=C(CSc1n[nH]c(C=Cc2ccc(F)cc2)n1)NC1CCCC1 +COCCCNC(=O)Nc1cnn(CC(F)F)c1 +COCCOc1ncccc1C(=O)NCC1CC1 +CCC(=O)Oc1cn(C2CC2)c2nc(CC)n3c4ccccc4nc3c12 +Cc1ccc(S(=O)(=O)N(C)CC(=O)NCCc2ccccc2)cc1 +CCS(=O)(=O)c1ccc(O)c(NC(=O)Cc2cccs2)c1 +Cc1noc(CC2COC3CN(C(=O)Cc4ccsc4)CC23)n1 +CCOC(=O)CN(C)Cc1csc(-c2ccccc2F)n1 +COc1cccc(Oc2cc(N3CCN(C(C)=O)CC3)ncn2)c1 +O=C(Nc1ccc(-c2nnc3n2CCCC3)cc1)c1ccnc(F)c1 +COc1ccc(NC(C)=O)cc1NS(=O)(=O)c1ccccc1C#N +O=C(NCc1ccccn1)c1cccnc1OCC(F)F +Cc1cc(-c2cnc(NCc3cccnc3)nc2C2CCCO2)on1 +Cc1ccccc1CC(=O)Nc1ccc(Cn2cccn2)cc1 +O=C(NCC1(O)CCCC1)c1cc(Br)ccc1Cl +NC(=O)CC1CCN(C(=O)NCCc2ccc3ccccc3n2)CC1 +CC(=O)Nc1ccc(C#CCNC(=O)CCC2CCCC2)cc1 +Cc1ccccc1-n1nnc(CO)c1CCOc1ccccc1 +COC(=O)Cc1ccc(OC(=O)C2CC=CC2)cc1 +N#Cc1ccc(CNC(=O)c2csc(S(N)(=O)=O)c2)cc1 +Cc1c(C(=O)NCC2(c3cccc(Cl)c3)CCOCC2)cnn1C +CN(CC(=O)OCc1cccc(F)c1)C(=O)c1cccs1 +COc1ccc(Cl)cc1NC(=O)CCSc1ccccn1 +COCC(C)NC(=O)CNc1ccc(OC)nc1 +Cn1c(C2CC2)nc2cc(CCn3cc(N)cn3)ccc21 +O=C(CCc1nccs1)NC1CCCN(c2ccccc2)C1=O +CCS(=O)(=O)NCC(C)(C)N1CCOCC1 +Cc1ccc(CS(=O)(=O)c2nc(C)cs2)cc1 +CN(C)C(=O)N1CCn2nc(CNc3ncnc4[nH]ccc34)cc2C1 +N#Cc1ccc(CNc2ccc(C(N)=O)cc2)c(F)c1 +CN(C)C(=O)CNC(=O)Nc1ccc(Oc2ccc(F)cc2)nc1 +CCN1CCN(C(=O)COc2c(C)cc(C)cc2C)CC1 +O=C(NCc1cn[nH]n1)c1cnc(-c2cccs2)s1 +COC(=O)C1CCCCN1Cc1cnn(-c2ccc(F)cc2)c1 +Cn1cc(-c2nc3c(cnn3Cc3cccc(F)c3)[nH]2)cn1 +CCc1ccccc1NS(=O)(=O)c1ccc(-n2cccn2)cc1 +CCn1nc(C(=O)NC(c2ccccc2F)C2CCCC2)ccc1=O +O=C(Cc1ccc2c(c1)CCC2)N1CCC(n2cncn2)CC1 +COc1cccc(CNC(=O)NC2CCc3c(O)cccc32)c1 +C=CCn1c(SCc2ccc(F)cc2)nnc1C1CC1 +CC(NS(=O)(=O)c1ccccc1)c1ccc(F)cc1 +CC1CN(c2ncc3c(n2)CCCC3NC(=O)C(C)C)CC(C)O1 +COc1ccc(CCN(Cc2ccccn2)C(=O)c2ccon2)cc1 +C=CCN(CC=C)C(=O)C(C)NC(=O)c1ccccc1C +Cn1cc(N)nc1Cc1ccccc1Br +CC(=O)NCCNC(=O)c1ccc(Cn2cccn2)cc1 +CCn1cc(S(=O)(=O)N2CCC(c3ccccc3)CC2)nc1C +CCC(C)(C)NC(=O)c1ccc(-n2c(C)nc3ccccc3c2=O)cc1 +Cc1nn(-c2ccccc2)c(C)c1C1NCCNC1=O +CCOC(=O)c1noc2nc(C)n(Cc3cccc(C#N)c3)c(=O)c12 +CC(C)c1ccc(C(=O)NC2(C(N)=O)CCCCC2)cc1 +Cc1cc(SC(C)c2ccc(F)cc2)nc(N)n1 +Cc1cc(NC(=O)CN2CCN(C(=O)NC(C)C(C)C)CC2)no1 +COc1ccc(S(=O)(=O)NC2CCc3ccccc32)cc1 +CC(Sc1cnn(C)c1)C(=O)c1ccc(Cl)cc1 +COCC(Nc1nc2ccccc2s1)C(N)=O +CCCCn1c(SCCCC#N)nc2ccccc2c1=O +Cc1ccc(C(=O)N2CCC(N3CCN(C)C3=O)CC2)c(C)c1 +CCC1(CO)CCCN(C(=O)CCc2ccc3c(c2)OCO3)C1 +Cc1cc(C)n(-c2ccc(CNC(=O)NCCC(C)C)cn2)n1 +COc1cc2ncn(CC(O)c3ccc(F)cc3)c(=O)c2cc1OC +CN(C(=O)C1CCCC1)c1ccccc1S(C)(=O)=O +CC(NC(=O)c1ccc(N2CCNC2=O)cc1)c1ccncc1 +O=C(CCSc1ccccc1Cl)NCCN1CCOCC1 +Cc1ccc(NC(=O)COc2ccccc2C#N)cc1S(C)(=O)=O +Cn1nc(-c2ccncc2)cc1NC(=O)c1n[nH]c2ccccc12 +COCC(C)(O)CNC(=O)Nc1ccccc1F +CN(Cc1ccc(F)c(F)c1)C(=O)c1cccn1Cc1cccnc1 +Cn1cc(CNC(=O)c2ccccc2SCC#N)cn1 +Cn1c(SCc2ccon2)nc2sc3c(c2c1=O)CCC3 +CN(C)c1ccccc1NS(=O)(=O)c1ccc(F)cc1 +CCc1noc(CC)c1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12 +CCC(=O)N1CCN(C(=O)c2cnc3snnc3c2)CC1 +Nc1cccc(CC(=O)N2CCN(c3ncccn3)CC2)c1 +Cn1cc(Br)cc1C(=O)Nc1ccncc1 +O=C(Cc1ccc2c(c1)OCCO2)Nc1cccc(Cl)c1 +Cc1ccsc1CNc1ccc2c(c1)CCC(=O)N2 +CCNc1c(CN2CC(C)CC2=O)c(C)nn1C +Cc1c(CN2CCOCC2)c(=O)n(-c2ccccc2)n1C +COc1ccc(OC)c(-c2nc3scc(C)n3c2N)c1 +CC1CCCCC1NC(=O)C(C)S(=O)(=O)c1nccn1C +O=C(CC1NCCc2ccccc21)NCc1ccccn1 +Cc1ccc(-c2nc3ccccc3n2CCCO)cc1N +C=CCn1c(C2CC(=O)N(C)C2)nc2ccccc21 +N#CCCN(CCC#N)c1ncnc(-n2ccnc2)c1N +CC(C)(C)NC(=O)c1ccc(NCC(=O)Nc2ccccc2F)cc1 +Cc1occc1C(=O)NCC(=O)N(C)Cc1nccn1C(F)F +Cc1nc(-c2cccc(NC(=O)CSc3nccn3C)c2)cs1 +COc1ccc(CNc2nc3cc(C#N)ccc3[nH]2)cc1 +N#Cc1ccc(Cl)c(NC(=O)c2cnn(-c3ccccc3)n2)c1 +Cc1n[nH]c(NCc2cccc(Cl)c2Cl)n1 +Cc1cc(CNC(=O)c2ccc3c(c2)OCO3)nc(N2CCCC2)n1 +Cc1nnc(SCCCOc2ccccc2)n1N +CC(C)(C)n1cc(CNc2cnn(-c3ncccn3)c2)cn1 +COc1ccc(C(=O)OCc2cc(C(C)=O)ccc2OC)c(F)c1 +CC1CCCCC1NC(=O)C1CCN(c2ccc(F)c(F)c2)C1=O +CCC(=O)NCCN1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +CCOC(=O)C1(O)CCN(C(=O)c2ccc(C)nc2)CC1 +NC(=O)c1cc(Cl)ccc1OCc1noc(-c2ccsc2)n1 +Cc1ccc(NC(=O)CSc2nnnn2C)c(N)c1 +COc1cccc(Nc2nnc(SCC(N)=O)s2)c1 +COc1ccccc1NC(=O)c1cnc2[nH]ccc2c1 +c1ccc(-c2nccc(CNCCn3cccn3)n2)cc1 +Cn1cc(C(=O)Oc2ccc3c(c2)CCC(=O)N3)c(C(F)(F)F)n1 +Cc1n[nH]cc1CNC(=O)CSc1nc2ccccc2s1 +N#CC1(NC(=O)c2cc3ccccc3o2)CCCCC1 +CC(=O)c1c(C)[nH]c(C(=O)OC2CCOC2=O)c1C +Cc1ccc(S(=O)(=O)NC(CO)c2ccccc2)cc1 +C=CCNC(=O)C1CC(=O)N(Cc2ccccn2)C1 +CC(NC(=O)Nc1ccc(Cl)c(Cl)c1)c1nc[nH]n1 +COc1ccc(-n2nnc(C(=O)Nc3nccs3)c2C(C)C)cc1 +Cn1ccnc1CN1CCCN(C(=O)c2ccoc2)CC1 +CCc1cccc(C)c1NC(=O)NCc1sccc1C +Cc1cc(Cl)ccc1OC(C)C(=O)NCCCN1CCCC1=O +O=C(NCCn1cnc2ccccc21)C1COCCO1 +COc1cccc(S(=O)(=O)N2CCCC(c3cnccn3)C2)c1 +CCc1ccc(C(=O)Nc2nc(C)c(C(=O)N(C)C)s2)s1 +Cc1cccc(N)c1NC(=O)Cn1cc(Cl)cn1 +CCn1c(SCC(=O)c2ccc[nH]2)nnc1-c1cccs1 +Cc1nc(C(=O)N2CCN(C3CCCC3O)CC2)cs1 +Cc1cc(OC(=O)CCC2CCCO2)ccc1Cl +O=C(Nc1ccccc1OC(F)(F)F)c1cccc2nccn12 +Cn1c(SC2CCOC2=O)nc2sc3c(c2c1=O)CCC3 +CN(C)C(C(=O)NCc1cc(=O)[nH]cn1)c1cccc(F)c1 +Cc1ccc(CNC(=O)Nc2ccccc2F)cc1 +N#CCCCN1CCN(S(=O)(=O)c2c(F)cccc2F)CC1 +CC(=O)c1c(C)nc(C)nc1SCc1csc(C2CC2)n1 +COc1cc(OC)c(C(=O)NCC(C)(C)c2ccncc2)cc1OC +Cc1noc(-c2ccco2)c1C(=O)NCCCOC(C)C +Cn1c(Cn2nc(-c3ccccc3)ccc2=O)cc(=O)n(C)c1=O +CNS(=O)(=O)CC(=O)NCc1ccc(-c2ccccc2F)o1 +CN1CCOC(C(=O)NCc2csc(CCc3ccccc3)n2)C1 +CC(C)(C)c1noc(COC(=O)COc2ccccc2C#N)n1 +CN(C)C(=O)CCC1CCCN(c2ccc(Cl)cn2)C1 +CCn1cc(C(=O)NCCc2cc(F)cc(F)c2)cn1 +O=C(Cn1nc(-n2cccn2)ccc1=O)Nc1ccc2c(c1)OCO2 +CCC(=O)Nc1ccc(C2=Nn3c(nnc(C)c3=O)SC2)cc1 +CC(C)CN1CCOC(CCNC(=O)c2cccc3nnnn23)C1 +CCOc1ccc(C(=O)Nc2ccc(C)cn2)cc1OCC +CC1CC1C(=O)OCC(=O)Nc1ccc2c(c1)OC(F)(F)O2 +O=C(C1CCCO1)N(Cc1ccc(C(F)(F)F)cc1)C1CC1 +O=C(OCC1COc2ccccc2O1)c1cscn1 +CCCCn1nc(C)nc1C(C)Oc1cccc(OC)c1 +Cc1cccc(-c2c(-c3ccsc3)n[nH]c2N)c1 +NC(=O)Nc1cccc(CNC(=O)C2CC2c2ccc(Cl)cc2)c1 +Cc1ccc(C2COCCN2Cc2sccc2C)o1 +C#CCN1CCC(C(=O)Nc2ccc(NC(N)=O)cc2)CC1 +CCc1cccc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)c1 +COc1cn(-c2ccccc2)nc1C(=O)NCCC(C)C +CCCN(CC(=O)Nc1ccccc1OC)C(=O)c1c(C)noc1C +Cc1cccc(-n2nnc(C(=O)Nc3ccccc3Cl)c2N)c1 +CCc1ccc(S(=O)(=O)NCCCn2ncccc2=O)cc1 +Nc1ccc(C=Cc2ccc(N)cc2Cl)c(Cl)c1 +CS(=O)(=O)c1ccccc1C(=O)Nc1ccc(Cl)cc1F +Cc1ccc(C(C)NC(=O)CCCOc2ccccc2)o1 +CCCOc1cccc(CN2CCOC(C(=O)OC)C2)c1 +CN(C(=O)NCc1ccc2c(c1)OCCCO2)C1CCC1 +CCCc1ccc(-c2cc(NC(=O)c3ccc(=O)n(C)c3)[nH]n2)cc1 +O=C(c1cc2ccccc2s1)N1CCC(n2cc(CO)nn2)CC1 +CC(=O)c1cccc(OCC(=O)N(CCC#N)c2cccc(C)c2)c1 +CC(C)n1cc(S(=O)(=O)NCC2CN3CCCCC3CO2)cn1 +CNS(=O)(=O)c1ccc2c(c1)N(Cc1noc(C(C)C)n1)CC2 +Fc1ccc(CN2CCCC(CN3CCOCC3)C2)cc1Cl +COc1ccc(OC)c(NC(=O)c2cc3ccccc3[nH]2)c1 +Cc1cccn2c(=O)c3cc(C(=O)N4CCCCC4)n(C)c3nc12 +COC(=O)C(C)NC(C)c1c(C)nc(C)[nH]c1=O +CCc1cc(=O)[nH]c(-c2cccc(NC(=O)C3CC4CCC3O4)c2)n1 +CC1Cc2ccccc2N1Cc1occc1C(=O)N1CCNC(=O)C1 +CCCOCC(=O)Nc1cccc(NC(=O)NCC)c1 +CC1Cc2ccccc2N1CCNS(=O)(=O)N(C)CCC#N +CC(OC(=O)c1cccs1)C(=O)NC1CCCC1 +Cc1[nH]ccc1C(=O)N1CC2CCC1CN(C(=O)c1ccccn1)C2 +COc1cccc(C(=O)N(C)CCOc2ccc(Cl)cc2)c1 +Cc1cc2c(cc1F)CCNC2CCC(=O)c1ccccc1 +COc1cc(CNc2cnn(-c3ncccn3)c2)ccc1OC(F)F +COc1ccc(OCCCC(=O)NC(C)(C)C)cc1 +O=C(NCC(O)c1ccsc1)c1cccc(OCC(F)F)n1 +CNC(=O)C1CN(C(=O)c2ccc(F)cc2F)c2ccccc2O1 +Cc1ccc(OCCNC(=O)c2cnccn2)cc1 +Cn1cc(CNC(=O)NCc2cc3ccccc3o2)cn1 +Cc1cc(C)n(Cc2cccc(NC(=O)c3ccnc(F)c3)c2)n1 +COc1ccc(C(=O)N(C)Cc2ccc(OC)cc2OC)cc1 +CC(=O)c1c(C)[nH]c(C(=O)NCCCN2CCOCC2)c1C +Cc1sc(NC(=O)c2ccc(F)cc2)c(C#N)c1C +COC(=O)NCCC(=O)NCC(C)(O)c1ccsc1 +C=CCn1c(N)cc(=O)nc1SCC(=O)Nc1cc(C)ccn1 +CC(=O)N1CCN(C(=O)CSc2ccc(C(C)C)cc2)CC1 +COC(=O)C(CC1CCCCC1)NC(=O)CN1CCOCC1 +COc1ccc(N2CC(NC(=O)C3CCCC3)CC2=O)cc1 +CC(C)(C)OC(=O)Nc1ccc(-c2cnc(=O)[nH]c2)cc1 +CC(Sc1nnc(-c2c[nH]c3ccccc23)o1)C(N)=O +O=C(Nc1ccc(Oc2ccc(F)cc2)cn1)c1ccncc1F +Cc1noc(CCNC(=O)c2cn(C)nc2-c2ccc(F)cc2F)n1 +OCC(O)C(O)C(O)c1cnc2ccccc2n1 +O=C(NCc1ncc[nH]1)c1ccc(Sc2ccccc2Cl)nn1 +Cc1ccc(S(=O)(=O)N(C)Cc2ccnn2C)cc1 +CC1CCCC(C#N)(NC(=O)Cc2ccc(F)c(F)c2)C1 +CCn1cc(C(=O)OCc2ccc(OC)c(OC)c2)cn1 +Cc1cccc(-c2nc(CSc3nnc(-c4ccco4)o3)no2)c1 +CC1CCCN(S(=O)(=O)N2CCN(c3cc(C#N)ccn3)CC2)C1 +COc1ccc(C(C)NC(=O)c2c(C)noc2C)cc1 +O=C(NCc1cc(F)cc2c1OCOC2)N1CCCCCC1 +O=C(NCC(=O)N1CCCC1c1ccccn1)C1CC1 +CC(C)C(=O)N1CCCCC1C(=O)NCC1Cc2ccccc2O1 +O=C(Cc1ccc(F)cc1F)NCc1ccc(N2CCCC2=O)cc1 +COc1ccccc1-c1csc(NC(=O)c2csc(C)n2)n1 +Cc1cccc(-n2nnnc2C(C)(C)NCc2ccco2)c1 +O=C(Nc1ccc(F)cc1)N1Cc2cncnc2C1 +COc1ccc(Cn2c(CO)nc3ccccc32)cc1 +Cc1c(C(=O)NC(C)CC(C)C)cnn1-c1ccncc1 +c1cncc(-c2noc(Cn3cnc4ccccc43)n2)c1 +Fc1ccc(CNc2cnn(CC(F)(F)F)c2)c2ncccc12 +CNC(=O)C1CCCN1C(=O)N=c1[nH]cc(C)s1 +COc1nc2ccccc2cc1-c1nc(C)ncc1C +CCCCc1nnc(NC(=O)N(C)CC(=O)Nc2ccccc2)s1 +CCn1cc(S(=O)(=O)N2CCN(c3ccc(F)cc3)CC2)cn1 +CN(CCO)C(=O)c1cc(-c2ccc(Cl)cc2)nc2ccccc12 +Nc1oc2c(c1C(=O)c1ccccc1)C(=O)CCC2 +CCOc1ccc(C(=O)N2CCCC(CNC(=O)C(C)C)C2)cc1 +CCc1ccccc1-n1c(Cc2ccncc2)n[nH]c1=O +O=C1CCC(COC(=O)c2ccc(-n3cnc4ccccc43)cc2)N1 +O=C(CCC1CCCCC1)NCC(=O)Nc1nccs1 +Cc1cc(C(C)(O)CNS(=O)(=O)Cc2cccc(F)c2)c(C)o1 +CCOc1nnc(CN2CCCC2c2noc(C3CC3)n2)s1 +Cc1nn(C)c(C)c1CC(C)NC(=O)N(C)C(C)C +Nc1ccc2c(NCCO)ncc(Br)c2c1 +CCCCn1nc(C)c(S(=O)(=O)N2CCc3ccccc32)c1C +Nc1cc(Cl)cc2nc(CCc3ccco3)oc12 +OCCc1ccc(Br)c2ccccc12 +COc1ccc(NC(C)=O)cc1NC(=O)CSc1nncs1 +CCc1n[nH]c(SCC(=O)Nc2ccc(C(C)=O)cc2)n1 +CC1(C)Oc2cc(CO)ccc2N(Cc2ccccc2)C1=O +OCC#CCSc1nnnn1-c1ccc(Cl)cc1 +O=C(c1cc(NS(=O)(=O)c2ccccc2)ccn1)N1CCCCC1 +CCCCNC(=O)Cc1noc2c(C(C)C)cc(N)cc12 +Cc1cccc(Cn2nc(C)cc2NC(=O)c2ccco2)c1 +CC1CCCC(NC(=O)COC(=O)c2ccc(O)cc2)C1C +CCc1nnc2n1N=Cc1cc3cc(C)ccc3nc1S2 +CC1CN(Cc2ccccc2)CCN1C(=O)c1ccc2cc[nH]c2c1 +CNC(=O)C(C)CN(C)C(=O)CCCn1ccc2cc(Cl)ccc21 +CN(Cc1csc2ccccc12)C(=O)Nc1nnc(C2CC2)s1 +Cc1ccc(C)c2c(=O)cc(CN3CCOCC(CO)C3)[nH]c12 +CC(=O)Nc1nc2ccc(CC(=O)NC(C)C)cc2s1 +O=C1CCCN1CCCNS(=O)(=O)c1ccc(F)cc1F +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)Nc2c(C)cccc2C)c1 +Fc1cc(C(F)(F)F)cc2c1C(c1ccco1)NCC2 +CCCOc1ccc2cc(C(=O)Nc3cccc(C)n3)c(=O)oc2c1 +Cn1nnnc1-c1cccc(C(=O)NCCN2CCOCC2)c1 +O=C(COc1ccc2ccc(=O)oc2c1)N1CCOCC1C1CC1 +Nc1cncc(S(=O)(=O)NCCOCCO)c1 +COC(=O)c1ccc(C(=O)Nc2ccc(N3CCCC3=O)cc2)cc1 +OCc1sc(CSc2ccccc2)nc1C1CC1 +N#Cc1nccnc1-c1cccc(Br)c1 +CCCCN(CCO)C(=O)Nc1cccc(F)c1 +NC(=O)c1csc(C(=O)N2CCCCCC2c2ccccc2)c1 +CCOc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1 +COc1ccc(-c2cnc(CCC(=O)N(C)C)o2)cc1 +NC1=C(c2nc3ccccc3s2)CC(=O)N1CCc1ccccc1 +O=C(NCc1c(F)c(F)cc(F)c1F)NC1CC=CC1 +COC(=O)Nc1cccc(NC(=O)CCc2cccc(F)c2)c1 +CC(c1ccco1)N(C)C(=O)CSc1nncs1 +COC(=O)c1[nH]nc(-c2ccccc2)c1C(=O)OC +COc1cccc2c1OCC(NC(=O)NCCCc1cn[nH]c1C)C2 +Cc1cnc2n(c1=O)CC(C(=O)NCc1ccccc1)CS2 +COc1ccc(CC(=O)N2CCN(c3ncccn3)CC2)cc1 +Cc1nsc2c1C(c1ccc(Sc3nncn3C)o1)CC(=O)N2 +CC1CCCN(C(=O)C(C)Cn2cc(Cl)cn2)C1 +CC(C)N(C)C(=O)C1CC(=O)N(c2ccccc2Br)C1 +CCn1c(N)c(C(=O)CN2CCCc3ccc(F)cc32)c(=O)[nH]c1=O +Cc1cc(C(=O)N(C)C2CC2)ccc1-n1cnnn1 +CC1CN(C(=O)OC(C)(C)C)CC(C)N1C(=O)c1cnns1 +CN(C(=O)Cn1cnc(C2CCC2)cc1=O)C1(C#N)CCCCC1 +COc1ccccc1CNC(=O)c1cnc(N2CCOCC2)nc1N +Cc1cc(NC(=O)COC(=O)c2cc(Cl)ccc2F)[nH]n1 +Cc1cnc(N2CC3CN(C(=O)c4cccs4)CC3C2)nc1 +COc1ccc(C)cc1NC(=O)c1ccc(NC(N)=O)cc1 +CC(C)N(Cc1ccc(C(F)(F)F)nc1)Cc1cnn(C)c1 +Cc1nnc2n1CCN(C(=O)c1n[nH]c3ccccc13)C2 +Cc1noc(C)c1C(=O)NCCc1ccc(O)cc1 +Cc1ccc(OCC(=O)NCc2cccc(NC(=O)C3CC3)c2)cc1 +O=C(Nc1cccc(N2CCOC2=O)c1)c1ccc(O)c(Cl)c1 +CCn1cc(NC(=O)Cc2cccc(C(F)(F)F)c2)cn1 +CCn1cc(C(=O)Nc2ccc3c(c2)COC3)c(C(C)C)n1 +CC(C)(C)CCC(=O)N1CCC(c2nc3ccccc3[nH]2)CC1 +Cc1n[nH]c(SCc2ccc(NC(=O)c3ccco3)cc2)n1 +Fc1ccc(CNCCc2nc(-c3ccccn3)cs2)cc1F +O=C(Nc1ccccc1N1CCCCCC1)c1cnns1 +COc1ccccc1OCC(=O)N1CCOc2c(N)cccc21 +CC(NC(=O)OC(C)(C)C)C(=O)NCC1CCCOC1 +Cc1cccc2c1C(=O)NC1(CCN(C(=O)C3CCCCC3)CC1)N2 +O=C(NCc1nccs1)c1ccc(-c2ccco2)[nH]c1=O +CCc1nsc(N2CCN(Cc3cccc4cn[nH]c34)CC2)n1 +Nc1ccc(S(=O)(=O)NCc2ccccn2)cc1 +Cc1oc(-c2ccccc2)nc1CC(=O)N1CCOC2CCCCC21 +O=C(COc1ccc2c(c1)CCC2)Nc1ccc2c(c1)OCO2 +Cc1ccc(Cl)cc1NC(=O)c1cccc(-n2cnnn2)c1 +O=C(NCCc1c(Cl)cccc1Cl)c1cnns1 +COC(=O)CCN(C)C(=O)c1ccc2c(c1)CCO2 +Cc1nc[nH]c1C(=O)N1CCCC(CCc2ccc(F)c(F)c2)C1 +CSc1ccc(CNC(=O)Cn2ccccc2=O)cc1 +N#CC1CC(=O)N(c2cc(Cl)ccc2Cl)C1 +Nc1cc2c(cc1SCc1ccccc1)OCCO2 +Cc1ccc(OCc2n[nH]c(-c3ccccn3)n2)cc1 +CCn1cc(NCc2cc(OC)cc(OC)c2)cn1 +CCc1cc2c(=O)nc(SCCCO)[nH]c2s1 +Cc1ccsc1CN(C)C(=O)NCc1cc[nH]n1 +CC(=O)Nc1cccc(C(=O)OCC2CCC(=O)N2)c1 +Cn1c(=O)c2nc(CCc3ccccn3)[nH]c2n(C)c1=O +CCC(CC)N(CCOC)c1c(N)c(C)nn1C +COc1cc(C(=O)NCC2Cc3ccccc3O2)cc(OC)c1C +CCC(CC)N(C)C(=O)CCc1nnc(-c2ccc(C)cc2)o1 +CN(Cc1cc2cc(F)ccc2[nH]1)C(=O)C1(Cn2cccn2)CC1 +CCS(=O)(=O)N(CCO)c1cc(Cl)ccc1OC +CC(NC(=O)Cn1c(C(F)(F)F)nc2ccccc21)c1ccncc1 +O=C(NCc1ccco1)C1CCCN1C(=O)c1ccc2ccccc2c1 +COc1ccccc1NC(=O)Nc1ccc(N)cc1Cl +O=C(Nc1cnc(-n2cccn2)nc1)Nc1ccc(F)c(Cl)c1 +OCC1CCCN1c1cc(NCC2CCOC2)ncn1 +COc1ccc(SCC(=O)N(C)Cc2cccc(C#N)c2)cc1 +COc1cc(F)ccc1NCC(=O)NCCC#N +Cc1cccc(OCC(=O)Nc2cc(C)ccc2O)c1 +O=C(NCc1nnc2ccccn12)c1ccc2ccccc2c1 +CC(C)CC(NC(=O)c1cc(Cl)ccn1)c1ccccc1 +COCCCOc1ccccc1NC(=O)Nc1cccc(C#N)c1 +CNC(=O)c1cccc(OC(=O)Cc2ccc(C(F)(F)F)cc2)c1 +CCCOc1ccccc1NC(=O)c1ccc(-n2cncn2)nc1 +CSc1cc(C(=O)N(C)Cc2cccc(C#N)c2)ccn1 +COc1ccccc1NC(=O)Cc1cn2ccsc2n1 +CC(NC(=O)NCC(=O)NC(C)(C)C)c1ccc(F)c(Cl)c1 +CCOc1ccc2nc(-c3ccc(N)cc3)[nH]c2c1 +Cc1cccc(C)c1NC(=O)CNC(=O)NCc1ccc(F)cc1 +Cc1ccc(NC(=O)c2cn3c(n2)COCC3)c(F)c1 +N#CCn1cccc(OCC(=O)N2CCCCCC2)c1=O +COc1ccc(-c2cc(-c3ccco3)nc(N)n2)c(OC)c1 +O=c1[nH]c(=O)n(CCCc2cccc3ccccc23)cc1Cl +CCC(C)(C)NC(=O)NCCCN1CCCCCC1=O +N#Cc1ccccc1NC(=O)COc1ccccc1F +CCc1nnc2c3cnn(-c4ccc(C)c(C)c4)c3ncn12 +Cc1noc(C)c1CN1CCOC2(CCCN(c3cccnc3)C2)C1 +Nc1cc(Cc2ccc(Cl)c(Cl)c2)nn1CCO +C#CCNC(=O)c1nc(S(C)(=O)=O)n2ccccc12 +CCOC(CC)C(=O)Nc1ccc(F)cc1Cl +Nc1ccc2nc(CC(=O)NCc3ccccn3)ccc2c1 +Cc1nnc(SCC(=O)NC(CO)Cc2ccccc2)s1 +O=C(c1ccc2c(c1)OCO2)N1CCC(c2nnc(C3CC3)o2)CC1 +O=C(NC1Cc2ccccc2C1)c1cncc(Br)c1 +Cc1ccc(NC(=O)c2ccc(N(C)C)nc2)c(F)c1 +O=c1[nH]nc2c(-c3nc(-c4cccc(Cl)c4)no3)cccn12 +CCCc1cc(-c2ccccc2C(C)=O)nc(C)n1 +COc1ccc(CC2CN(C(=O)c3cc(C4CC4)n[nH]3)CCO2)cc1 +COc1ccc(-c2nnc(SC3CCCCNC3=O)o2)cc1 +COc1ccc(C(=O)CCC(=O)NC2CCCCCC2)cc1OC +COc1cccn(Cc2cc3c(cc2Cl)OCO3)c1=O +Cn1ccc(-c2nnc(NC(=O)c3ccncc3)o2)n1 +CC(=O)Nc1ccc(OCc2nc(C)cs2)cc1 +CCC(=O)N1CCN(CC(=O)c2cc(C)n(C3CC3)c2C)CC1 +O=C(Cc1c[nH]c2ccccc12)NCc1nc(-c2ccco2)n[nH]1 +CC(C)CN1C(=O)c2ccccc2NC1c1ccc(OC(C)C#N)cc1 +Cc1occc1C(=O)N1CC2CC3CC(C2)CC1C3 +O=C(Cc1cccc2ccccc12)N(CC1CCCO1)c1ccncc1 +COc1cccc(-c2nc3ccccn3c2CO)c1 +CCOc1cc(F)ccc1NC(=O)c1cnc(C)cn1 +CN(C)c1ccc(NC(=O)c2c(F)cccc2Cl)cn1 +COc1ccc(CC2CN(Cc3nc(C)cs3)CCC2OC)cc1 +CC1CC1C(=O)NCc1cn2cc(Br)ccc2n1 +COC(=O)c1ccc2c(c1)sc(=NC(=O)c1cc(C)no1)n2C +Cc1cc(C(=O)C2CCCN2C(=O)CC(C)C)ccc1F +Cc1oc(S(=O)(=O)N(C)C)cc1C(=O)NCc1cccc(F)c1 +Cc1nc2cc(-c3ccc4c(c3)OCO4)ccc2c(=O)[nH]1 +COc1ccc(NC(C)=O)c(NCCc2ccc3c(c2)CCO3)c1 +CC(c1ccccc1F)N(C)C(=O)NCC(=O)N1CCCC1 +Cc1cc(NC(=O)CSc2ccc(Cl)cc2)n(C(C)C)n1 +COCC(=O)NC(C(=O)Nc1cccc(F)c1)C(C)C +COc1ccc(NC(=O)c2cnc3ccc(C)cn23)cc1Cl +Nc1cccc2c1CN(c1cc(F)c(F)cc1F)C2 +COC(=O)c1sccc1NC(=O)Nc1cccn2cnnc12 +Cc1ccccc1-n1nccc1NC(=O)NC1CCCCNC1=O +NC(=O)c1oc2cc(Br)ccc2c1N +Cc1ccn2c(=NC(=O)Cn3cnc4c(C)cccc4c3=O)[nH]nc2c1 +Cc1nnc(SCC(=O)N2CCCC(C)C2)s1 +Cc1noc(C)c1C(=O)N1CCCC2(CC(C)CO2)C1 +CCOc1cccc(C(=O)NCc2c(C)nc3cc(=O)[nH]n3c2C)c1 +O=C(CCC1Cc2ccccc2NC1=O)NCc1ccco1 +CCOC(=O)C1CCCN1C1=NS(=O)(=O)c2ccccc21 +COC(=O)c1ccccc1NC(=O)C1CCN(CC(F)(F)F)CC1 +CCOC(=O)c1cc(-c2cc(C)cc(C)c2OC)n[nH]1 +O=C(NCCc1nnc2n1CCC2)c1csnn1 +O=S(=O)(CCc1ccccc1)N1CCCCC1CCO +O=C(Nc1c[nH]cc(Br)c1=O)c1cccc2c1OCO2 +O=C(Nc1ccc(Cc2nc3ccccc3[nH]2)cc1)c1ccncc1 +Cc1ccc(C(NC(=O)CCc2c(C)noc2C)C2CC2)cc1 +Cc1ccc(CC(=O)NCc2cccnc2)cc1C +O=C(NCCc1cccnc1)C1CC(=O)N(Cc2ccco2)C1 +CCCC(C)NC(=O)C1CCCN(C(=O)c2ccoc2)C1 +Cc1ccc(C(=O)Nc2c(C(N)=O)oc3ccccc23)s1 +CCNc1nc(C(=O)Nc2cc(F)ccc2OC)cs1 +C=CCCC(=O)N1CCC2(CCC(=O)N(Cc3ccccc3)C2)CC1 +CC(=O)c1cn(CC(=O)N(C)Cc2ccccc2)c2ccccc12 +CCCc1c(C)[nH]c2c(Br)cccc2c1=O +COc1ccccc1-c1nnc2n1N=C(O)CS2 +Cc1ccc(CN(C)C(=O)C2(C#N)CCCCC2)cc1 +CC(C)C(Sc1nnc(-c2cccnc2)n1C1CC1)C(=O)N(C)C +Cc1ccc(C(=O)N2CCC3(CC(N4CCCC4=O)CCO3)C2)s1 +CCCC(=O)c1ccc(S(=O)(=O)CCO)cc1 +CCNS(=O)(=O)c1ccc(OC)c(-c2noc(CC)n2)c1 +CCOc1ccc(NC(=O)c2cccnc2OCC(F)F)c(C)c1 +Cc1cc(NC(=O)COc2ccc(Cl)cc2Cl)nc(=O)[nH]1 +CC(C)COCC(C)NC(=O)Cc1cccc(F)c1F +CCn1ncc(-c2cc(C(F)F)n3ncc(C#N)c3n2)c1C +COCCC1(O)CCN(C(=O)NCCc2ccccc2F)CC1C +O=C(COc1ccccc1)Nc1cccc(Oc2cnccn2)c1 +Cc1n[nH]c(C)c1NS(=O)(=O)N1CC(C)OC(C)C1 +CCNc1ncc(C(=O)NCCc2nc3c(s2)CCCC3)cn1 +CCCNC(=O)c1cnn(-c2cc(C)ncn2)c1N +CCOc1ccc(NS(=O)(=O)c2ccc(F)cc2C)cc1CO +Cc1nc(NCCC#N)cc(-c2cncc(-c3ccccc3)c2)n1 +CCc1c(C)sc2nc(-c3ccc(O)cc3)[nH]c(=O)c12 +O=C(Nc1ccccc1)c1nc(-n2cnnc2)ccc1Br +C=CCSc1nc2c(cnn2-c2ccccc2)c(=O)n1N +COc1cc(-c2noc(-c3ccc(O)cc3)n2)c(OC)c2c1OCO2 +Cn1cnnc1-c1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)cc1 +Cc1oc(C(=O)Nc2cc(F)ccc2Cl)cc1S(N)(=O)=O +CCc1cc(C#N)c(NC(=O)C(C)Oc2ccccc2C#N)s1 +CC(Sc1ncnc2nc[nH]c12)c1nc2ccccc2c(=O)[nH]1 +CCN(CC)C(=O)Nc1ccc(F)cc1OC(F)F +NC(=O)c1cccc(Cn2c(-c3ccccn3)noc2=O)c1 +N#CCCN(Cc1cccnc1)C(=O)Cc1ccc(-n2cnnn2)cc1 +CC(C)n1cc(C(=O)NCc2ccc3c(c2)CCCO3)cn1 +CNc1c(NS(=O)(=O)c2ccccc2F)c(=O)oc2ccccc12 +Cc1ccc(CN(C(=O)Cn2cncn2)C2CC2)s1 +CCc1ccsc1C(=O)N1CCn2cccc2C1C +COc1ccccc1-n1cnnc1Cc1ccncc1 +O=C(NCCCn1nc2n(c1=O)CCCC2)NC1CC1 +Cc1cccc(CNc2ccc(C(=O)N3CC(C)OC(C)C3)cc2)c1 +CC1CCCN(C(=O)C2CCN(C(=O)NCc3ccccn3)CC2)C1 +Cc1cc2c(cc1NC(=O)N1C3CCC1CN(C)C(=O)C3)OCCO2 +CCCOC(=O)C1=C(C)N(CC)C(=O)NC1c1ccccn1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccc(F)c(F)c2)cc1 +Cc1cnc(C(=O)N2CCCC(c3[nH]ncc3-c3ccccc3)C2)cn1 +Cc1ccc(C(=O)N2CCc3[nH]c4ccnn4c(=O)c3C2)cc1F +Cc1ccc2nc(NCCNC(=O)c3ccco3)c(C#N)cc2c1 +CCN(CC)C(=O)N1CCC(C(=O)OCCOC)CC1 +CC(C(=O)N1CCc2ccccc2C1)N1Cc2ccccc2C1=O +Cc1nn(C)c(C)c1NC(=O)c1nn(C)c2ccc(F)cc2c1=O +CCCN(CC1CCCCO1)C(=O)Cc1c(F)cccc1F +CC(=O)N1CC2c3ccccc3C(NC(=O)c3scnc3C)C2C1 +Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccnc(OC2CCC2)c1 +CNC(=O)c1ccc(CN(C)C(=O)c2ccc3[nH]cnc3c2)cc1 +CCc1c(C(=O)Nc2cccc(-c3ncc[nH]3)c2)[nH]c(C)c1C(C)=O +O=C(Nc1cccc(Cl)c1F)C1COc2ccccc2O1 +Cc1cccc(S(=O)(=O)NC(C)C(=O)N2CCCCC2C)c1 +O=C(CSc1nc2ccccc2o1)Nc1ccc2c(c1)COC2 +COc1ccc(F)cc1C(=O)OCc1nc(N)nc(N)n1 +Cc1ccc(-c2ccnc(NCC(C)C)n2)c(C)n1 +COC(=O)C(Cc1cccc(Br)c1)NC(C)=O +COc1cc(NC(=O)NC2Cc3ccccc3C2)cc(OC)c1 +Cc1ccccc1-c1noc(-c2cn(C)c3ccc(F)cc3c2=O)n1 +CC(=O)N1CCc2cc(NC(=O)c3ccc(F)cc3F)ccc21 +Cc1cc(C)c(C(=O)CSc2nnc(C3CC3)n2C)c(C)c1 +O=C(c1ccc(Cl)cc1)N1CCC(OCc2ccc(F)cc2)CC1 +CC(=O)Nc1ccc(S(=O)(=O)NCc2ccco2)cc1Cl +Nc1ccn(Cc2ccc(Br)cc2)c(=O)c1 +Cn1nccc1NC(=O)Cn1ccc(-c2cccs2)n1 +O=C1COc2ccc(C(=O)Nc3nccs3)cc2N1 +CC(=O)Nc1ccc(NC(=O)NC(C)(C)CO)c(C(F)(F)F)c1 +CCC(C)C(C)NC(=O)c1ccc(C(F)(F)F)nc1 +CC(C)(C)C(=O)CNC(=O)c1ccc(Br)cc1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(OC(F)(F)F)cc1 +COc1ccc(CNC(=O)C2C=CCN2C(=O)c2cccs2)cc1 +CCCCOC(C)C(=O)Nc1cc(OC)ccc1F +Cc1ccc(C(O)CCC(=O)NC2CCCCC2)cc1C +CCc1nc(CNc2ccc(C(F)(F)F)cc2Cl)no1 +CCc1c(C#N)nnn1CCCCOc1cccc(C)c1 +CCNC(=O)N1CCC(NC(=O)c2c(C)noc2-c2ccccc2)C1 +Cc1c(N)cccc1NC(=O)CCSc1nccn1C +CN(Cc1cccc(Cl)c1)C(=O)c1ccc(S(C)(=O)=O)cc1 +COc1ccc(-c2csc(NC(=O)c3cnc(C)cn3)n2)cc1F +CC(C)C(=O)NC1COC2(CCN(C(=O)Cc3ccccn3)CC2)C1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)NCC(C)CC(C)O)c1 +Cc1ccc2nc(SCC(=O)N3CCCCCC3)nc(=O)n2c1 +CC1CN(CCCNC(=O)COC2CCCCC2)CC(C)O1 +CCOC(=O)C1=C(CN2CCc3ccccc3C2)NC(=O)NC1 +COc1cccc2cc(C(=O)Nc3ccccc3C(C)=O)oc12 +CC(CN1CCCC1=O)NC(=O)c1cc(Cl)c2c(c1)OCO2 +Cc1sc(NC(=O)NC2CCCCC2)c(C(N)=O)c1C +Cc1cccc(OCC(=O)Nc2ccc(OCC#N)cc2)c1 +O=C1c2ccccc2CC(O)(c2ccccc2)C2CCCCN12 +Cc1nccn1-c1ccc(C(C)NC(=O)NC(C)C(C)C)cc1 +c1coc(-c2nnc(Cn3ccc(C4CC4)n3)o2)c1 +CCN(Cc1cnc(-c2cccs2)s1)CC1CCCO1 +O=C1NC(CSc2ncn[nH]2)Nc2ccccc21 +O=C(Nc1n[nH]c2c(Cl)cccc12)c1c[nH]nc1-c1cccnc1 +Cc1ccc(NC(=O)c2cc(C)nc3onc(C)c23)nc1 +Cc1[nH]c2nc(C(=O)NCc3ccccc3)nn2c(=O)c1C +Cc1nc(-c2cnn(C)c2)n(-c2cccc(C(F)(F)F)c2)n1 +COc1cccc(C(=O)Nc2ccc(OC(F)F)cc2)c1 +NC(=O)c1cc(Cl)ccc1OCC(=O)N1CCC1 +COCC(=O)Nc1nnc(SCc2ccccc2F)s1 +Cc1cc(=O)oc(C)c1C(=O)Nc1ccc(F)cc1 +COCC(NC(=O)c1ccccc1SC(C)C)C(N)=O +Cc1cc(NC(=O)c2ccccc2OC(C)C)ccc1C(=O)N(C)C +CCOc1ccc(OCC(=O)NC(C)CC)cc1 +CC1CCC(NC(=O)c2ccc(CN3CCCC3=O)cc2)CC1 +CC(C)c1ccc(N2CCCCS2(=O)=O)cc1 +Nc1cccc2ccnc(C(=O)Nc3ccccn3)c12 +Cc1cc(C(C)NC(=O)NCCc2cccs2)c(C)o1 +Cc1cc(C)n(Cc2ccc(-c3noc(C(=O)NCCO)n3)cc2)n1 +CC(C)c1csc(C(C#N)C(=O)c2cccc(-c3ccoc3)c2)n1 +COC(=O)CCN(CC1CCCO1)C(=O)c1cccc2c1OCCO2 +CCN(CC(=O)NC)S(=O)(=O)c1ccc(C(=O)NC)cc1 +Cc1ccc(NC(=O)C(C)Sc2nc(N)cc(N)n2)cc1F +Cn1cc(C2CCCN2C(=O)c2csc(C3CC3)n2)cn1 +O=C(NC1CCCCC1)c1cnc2c(F)cccc2c1O +CS(=O)(=O)c1cc(-c2ccccc2)nn1-c1ccccc1 +O=C(NCCN1CCOCC1)c1ccccc1C(=O)c1ccccc1 +CC(CC(=O)c1cccs1)NC(=O)c1csnn1 +COC(=O)CCC(=O)NC(C)(C)c1ccc(F)cc1Cl +CC(=O)N1CCC(NS(=O)(=O)c2cc(Cl)ccc2C)CC1 +COC(C)(C)c1noc(-c2cc(C)nc3c2cnn3C)n1 +COc1cccc(CNC(=O)Nc2nnc3ccccn23)c1 +CC(C)(C(=O)NCc1ccnc(OC2CCC2)c1)c1cccc(F)c1 +CCCCc1nc(C)sc1C(=O)Nc1ccc(OC)nc1 +COC(=O)C(C)N1CCC(Oc2ccccn2)CC1 +CC(C)c1noc(C2CCN(C(=O)c3ccc(Cl)cc3)CC2)n1 +O=C(CCc1ccc(-c2ccccc2)o1)NCCc1ccccn1 +COCCNC(=O)C(C)Oc1ccc(Cl)c(C)c1 +CC(C1CC1)N(C)C(=O)c1ccc(-n2ncc(C#N)c2N)cc1 +FC(F)(F)c1ccccc1CNCc1cnn(-c2ccccc2)c1 +NC(=O)CCn1nc(-c2cccnc2)c2c1CCNC2 +Cc1cc(NC(=O)c2cnn(-c3ccccn3)c2C)c2ncccc2c1 +COc1cc(C(C)O)ccc1OC(C)C(=O)N(C)C +COCC(=O)NC(C(=O)N(C)c1ccc2ccccc2c1)C(C)C +Cc1c(NC(=O)C2CC3CCC2O3)cccc1C(=O)N1CCCC1 +O=C(OCC(=O)N1CCc2ccccc21)c1ccc(F)cc1 +CC(C)CC(=O)N1CCN(c2nc(-c3ccsc3)cs2)CC1 +CC1=C(C(=O)Nc2ccccc2)C(c2sccc2C)NC(=O)N1 +Cc1cc(CN2CC3OCC(C(=O)NCC4CC4)C3C2)no1 +O=C1COc2cc(NC(=O)c3c(F)cccc3Cl)ccc2N1 +O=C(NCCCc1nc2ccccc2s1)NCc1ccncc1 +CC(NC(=O)N1CCC2(CCCCC2)CC1)c1nncn1C +CCCN(CC(=O)OCC)C(=O)c1cc2ccccc2[nH]1 +Cn1cc(C(=O)Oc2ccc3nccnc3c2)cn1 +O=C1CC(c2noc(-c3ccccn3)n2)CN1CCc1ccccc1 +O=S(=O)(NCC#Cc1ccccc1)c1cccc(Cl)c1 +O=C(NCc1cccnc1)c1ccc(-c2ccc(Cl)cc2)o1 +Nc1coc(C(=O)Cc2ccccc2Br)c1 +CN(CC(=O)NCC(F)(F)F)C(=O)CC1OC(=O)c2ccccc21 +CSc1nnnn1-c1ccc(C(=O)OCc2ccccc2F)cc1 +O=S(=O)(NC1CC1)c1ccc(Br)cc1 +COc1ccccc1CNC(=O)COc1ccc(C)nc1 +Cc1cc(=O)oc(C)c1C(=O)Oc1cccc(Cl)c1 +N#Cc1ccccc1OCC(=O)Nc1nc(CC(N)=O)cs1 +COC(=O)c1ccc(NC(=O)CS(=O)(=O)c2cccs2)cc1 +CCCNC(=O)c1cn(CCC)c2nc(C)ccc2c1=O +O=C(CCc1ccccc1)NCC(c1ccccc1)N1CCOCC1 +Nc1ccc(C(=O)Nc2nc3ccc4ncsc4c3s2)cc1 +C=CCn1c(N)nnc1SCc1nc(-c2ccsc2)oc1C +COc1cccc(C(=O)CN2C(=O)CNc3ccccc32)c1 +CCCCn1c(N)c(N(C)Cc2cccnc2)c(=O)[nH]c1=O +COc1cc(N)ccc1NC(=O)COCC(F)(F)F +O=C(CCNCC(F)(F)F)N1CCOC(c2ccc(F)cc2)C1 +Cc1ccc2oc(C(=O)Nc3cccc(-n4cnnc4)c3)cc2c1 +C=CCNC(=O)N1CCN(c2ncccc2C#N)CC1 +COCC(C)N1CCN(C(=O)c2ccc(C(=O)N(C)C)cc2)CC1 +CCNC(=O)c1cccc(NC(=O)c2ccnc(SC)c2)c1 +CCCn1c(C)nnc1SCC(=O)Nc1ccc(F)cc1Cl +Cc1cc(N2CCNC(=O)CC2)n2nc(C(F)(F)F)nc2n1 +CC(C)NC(=O)Nc1cccc(C(=O)Nc2ccc(F)cn2)c1 +Cc1ccc2cnn(CCC(=O)N3CCC(C(N)=O)CC3)c2c1 +COc1ccc(S(=O)(=O)CC2CCCO2)cc1 +CC(C)NC(=O)COc1cccc(NC(=O)c2ccccc2)c1 +CCCS(=O)(=O)NCc1ccc(N2CCCC2)nc1 +CCn1nnnc1-c1cccc(NCc2nnc(C(C)(C)C)o2)c1 +Cc1cc(C)nc(NC(=O)c2cc(Cl)ccc2O)n1 +CC1CCN(S(=O)(=O)c2cc(-c3ccc(=O)[nH]n3)cs2)CC1 +O=c1[nH]ncc(NCCCOc2ccccc2F)c1Cl +O=C(c1ccc(-c2nc3ccccc3s2)cc1)N1CCOCC1 +COc1ccc(C(=O)NCc2csc3c2CCCC3)cc1OC +CCS(=O)(=O)N1CCN(c2ccc(Nc3ccccn3)nn2)CC1 +COC(=O)N1CCC(NC(=O)NC(C)c2ccncc2)CC1 +COCC1c2nnn(CC3CC3)c2CCN1C(=O)c1ccc(C)o1 +Cc1cc(C)c(NC(=O)C2CCN(S(C)(=O)=O)CC2)c(C)n1 +Cn1c(SCCOc2ccccc2)nnc1-c1cccnc1 +Cc1cc(=O)[nH]c(-c2cccc(NC(=O)c3cccs3)c2)n1 +Cc1cc(C)n2nc(SCC(F)(F)F)nc2n1 +CCCC(C)N(C)C(=O)Nc1ccc(C(C)=O)cc1 +FC(F)(F)c1nc2c(cnn2-c2cccc(Cl)c2)c2nnnn12 +COc1ccc(C(=O)C(C)OC(=O)c2c(C)cc(=O)oc2C)cc1 +O=C(NCCC1CCCO1)c1cc2c([nH]c1=O)CCC2 +Cc1nc2scc(-c3ccc(F)cc3)c2c(=O)n1-n1cccc1 +CC(C)(C)NC(=O)N(Cc1ccoc1)Cc1cccs1 +Cc1ccc(-c2n[nH]c(NC(=O)c3ccc4c(c3)OCC(=O)N4)n2)cc1 +O=C(NC1CCCCCC1)c1cccc(N2CCCC2=O)c1 +CN(CCOc1cccc(Cl)c1)C(=O)c1ccccc1 +CC(C)Oc1ccccc1-c1cc(CO)c(C2CC2)o1 +CN(C)c1cccc(OCc2nc(CCO)cs2)c1 +CC(C)c1n[nH]c(C2CN(CCc3ccncc3)CCO2)n1 +Nc1ccccc1Sc1nnc(C2CC2)n1C1CC1 +CCc1csc(NC(=O)Cc2nc(-c3ccco3)oc2C)n1 +CCOCCNC(=O)Cc1cc(Cl)ccc1Cl +N#Cc1cc(Br)c(N)cc1C(F)(F)F +CNC(=O)c1ccc(OC)c(NCCOc2ccc(F)cc2)c1 +COc1ccc(N(C)S(C)(=O)=O)cc1C(N)=O +COc1cccc2cc(C(=O)N(C)C3CCCCC3)c(=O)oc12 +CC1CN(C2CCN(C(=O)c3ncoc3C3CC3)CC2)CC(C)O1 +O=C(CCC(=O)c1cccs1)OCC(=O)N1CCc2ccccc21 +COc1c(O)c(Cl)cc2c1C(C(O)C(C)C)NCC2 +CCOc1ccccc1N1CCN(C(=O)C2CC2C)CC1 +CC(C)C(=O)NC1(c2ccc(F)cc2F)CCOCC1 +CCCOc1ccc(NC(=O)CNC(C)=O)c(C)c1 +N#Cc1cnc(SCC(=O)N(Cc2ccsc2)C2CC2)nc1N +Cn1cc(NC(=O)C2CCN(c3ccc(F)cc3)C2=O)ccc1=O +CC(=O)N(C)C1CCN(C(=O)Nc2cc(C)cc(C)n2)CC1 +CC(NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)NCC(F)(F)F +O=C(c1ccoc1-c1ccccc1O)N1CCOCC1 +CCCCCNS(=O)(=O)c1ccc(F)c(S(C)(=O)=O)c1 +CC(Oc1ccc(OC(=O)c2cn(C)nc2C(C)(C)C)cc1)C(N)=O +Cc1ccsc1C(=O)NCCNC(=O)c1ccn[nH]1 +Cc1cc(C(=O)NCCCN2CCOCC2)c(C)n1C(C)C +CCn1nnnc1SC(C)C(=O)Nc1ncnc2nc[nH]c12 +Cc1ccc(F)cc1NC(=O)C(C)Sc1ccccn1 +CC(C)(C)NC(=O)c1cccc(NC(=O)c2ccc(C#N)cc2)c1 +Cc1ccccc1C(=O)Nc1nnc(-c2ccc(N)cc2)s1 +CN(Cc1ccncn1)C(=O)c1cn(CC2CCCO2)nn1 +CC(C)NC(=O)c1ccc(OCC2CCCN2C(=O)C(C)C)cc1 +CCc1onc(C)c1NC(=O)c1cc(-c2ccc(F)cc2)on1 +Cc1ccccc1CNS(=O)(=O)CCn1c(=O)oc2ccccc21 +O=C1OCCN1Cc1sccc1Br +COc1ccc(CCNC(=O)NCc2nc(C)no2)cc1 +Cc1ccc(NCC(=O)Nc2ccc(F)cc2)cc1-n1cnnn1 +Cc1cc2c(cc3c(=O)n(CC(=O)NC4CCC4)nc(C)n32)s1 +COC(=O)c1ccoc1COC(=O)c1cccc(C)c1NC(C)=O +CNS(=O)(=O)c1ccc(NC(=O)c2ccc(COC)cc2)cc1 +CCOc1ccc(C)cc1-c1nc2cc(CO)ccn2c1N +Cc1csc(SCc2nc(-c3ccco3)no2)n1 +COc1cccc(-c2cc(-c3ccc(C)o3)nc(N)n2)c1OC +O=C(NCCCOC1CCOCC1)C1COc2ccc(F)cc2C1 +COc1ccc(NC(=O)NCC2(O)CCOCC2)cc1 +O=C(OCc1ccccn1)c1cc(F)cc(Br)c1 +Cc1cccc(-c2nnc(SCC(=O)N(C)C)n2C)c1 +Cc1ccc2c(n1)OCCN2C(=O)COc1ccccc1F +COC(=O)C(C)n1cnc2sc(-c3ccccc3)cc2c1=O +CC(C)(C)C(=O)NCC(=O)N1CCOC(c2ccccc2)C1 +CS(=O)(=O)N1CCC(CNC(=O)c2scnc2C2CC2)CC1 +O=C(C1CCCN(C(=O)C2CC=CCC2)C1)N1CCOCC1 +Cc1noc(CN(C)C(=O)c2ccc(-c3ccccc3)[nH]2)n1 +CCCN1C(=O)c2ccccc2NC1c1ccccc1OCCOC +CCCCNC(=O)CSc1cc(-n2nc(C)cc2C)ncn1 +CN(CC(=O)NCc1ccoc1)c1ccc(Cl)cn1 +Cc1ccc(C(=O)N2CCN(C(=O)c3ccncc3F)CC2)cc1 +O=C(NCc1cccs1)c1nc(-c2ccc(F)cc2)no1 +O=C(Cc1ccncc1)N1CCC2(CC1)CC(c1ccccc1)CO2 +CCN(Cc1ccccc1)C(=O)c1cc2ccccn2n1 +COc1ccccc1CNC(=O)CCn1ncc2c(Cl)cccc21 +CC12CCC(C(=O)NC3CCCCC3)(CC1=O)C2(C)C +COc1ccc(CNc2ccc3nc(N)nn3c2C)cc1OC +O=C1CCC(C(=O)N(CCO)C2CCCCC2)N1 +CN(C)c1nc(N)nc(Cn2cc(Br)cn2)n1 +CCCC(C)(NC(=O)c1cc(Br)cn1C)C(=O)OC +O=C(c1n[nH]c(=O)c2ccccc12)N1CCc2ccccc2C1 +N#Cc1cnn(C2CCCOc3ccc(F)cc32)c1N +Cc1cc(N2CCC(c3noc(C)n3)CC2)nc(-c2ccccn2)n1 +Cc1nn(C)cc1C(=O)N1CCN(c2ccccc2F)CC1 +N#CC(NC(=O)COc1ccccc1)C1CCCCC1 +CC(C)(C)c1ccc(NC(=O)c2cccc(OCC(F)F)n2)nn1 +Cc1nc(S(=O)(=O)N2CCc3[nH]ncc3C2)cn1C +CN(C(=O)c1cccc(NC(=O)NC2CC2)c1)C1CC1 +COC(=O)Cc1nn(Cc2ccccc2)c(=O)c2ccccc12 +Nc1cnnc(N2CCN(Cc3ccccn3)CC2)c1Cl +O=c1ccc(-c2ccco2)nn1Cc1cccc(Br)c1 +N#Cc1cnn(C(=O)COc2ccc(Oc3ccccc3)cc2)c1N +COC(=O)c1cccc(Nc2nc(C)cc(=O)[nH]2)c1 +Fc1cccc(F)c1-n1nc(C2CC2)c2c1CCNC2 +COC(C)(C)C(=O)NCCc1ccccc1C(F)(F)F +Cc1nc(C(=O)Nc2cccc(-c3ccn[nH]3)c2)cs1 +CCOC(=O)CSc1nc2nccc(-c3cccc(OC)c3)n2n1 +COCC(C)Nc1ncnc(Nc2cc(Cl)ccc2OC)c1N +CCOc1ccccc1S(=O)(=O)NCC1(O)CCCC1 +Cc1csc(SCC(=O)Nc2ccnn2C2CCCC2)n1 +CCC(=O)N1CCCC(C(=O)NC(C)(C)C(=O)OC)C1 +NS(=O)(=O)c1ccc(OCCn2cc(-c3ccccc3)cn2)cc1 +Cn1cc(C#N)c(=O)c2cc(Br)ccc21 +Cc1cc(C(=O)NCc2ccc(F)cc2)ccc1N +CCNc1ncnc(Nc2ccccc2Cl)c1N +CN(c1ccc(F)c(N)c1)S(=O)(=O)c1ccccc1 +CCOC(=O)C(N)c1c(F)ccc(Br)c1F +CC(NC(=O)N(C)Cc1ccccn1)c1cccc(S(N)(=O)=O)c1 +Clc1ccc(NCc2nnnn2-c2ccccc2)cc1 +CNC(=O)COC(=O)CCc1ccccc1Br +CC(Sc1ccccn1)C(=O)Nc1cccc2[nH]cnc12 +O=C(NCCn1ncccc1=O)c1cc(-c2ccc(F)cc2)n[nH]1 +Cc1ccc(CC(C)NC(=O)C2CCCO2)s1 +CCc1nn(C)c(OC)c1CNc1cnn(-c2ccccc2)c1 +Cc1nc(N2CCC(O)C2)ncc1S(C)(=O)=O +COc1cc(OC)cc(-c2nc3cc(N)cc(C)c3o2)c1 +COc1ccccc1CC(C)(C)NC(=O)Cc1ccc[nH]1 +CCNC(=O)CCC1CCCN(c2cc(NC3CC3)ncn2)C1 +CCc1onc(C)c1NC(=O)NC(C)(CCO)COC +COCCNC(=O)NC1CCSc2c(F)cccc21 +CCN(CC)C(=O)Cn1nnc(-c2ccc(OC)cc2)n1 +COCCCNC(=O)c1ccc(NC(=O)C2CCCO2)cc1 +CCc1nc(-c2cccc(NC(=O)c3ccc(C#N)cc3F)c2)no1 +Cc1c(C(=O)N(C)C)cccc1N(C)S(C)(=O)=O +O=C(Nc1nc(-c2ccco2)cs1)c1ccccc1 +CCn1c(C)nc2cc(S(=O)(=O)Nc3ccc(C)cc3)ccc21 +COc1ccc(C2CC(=O)N(CC(N)=O)c3ccccc3S2)cc1 +COc1ccccc1CN1C(=O)OCC1C(=O)NCCn1cccn1 +O=C(CN1CCOC(c2ccc(F)c(Cl)c2)C1)NCC1CCC1 +COC(=O)c1cccc(CC(=O)Nc2nonc2C)c1 +COC(=O)CNC(=O)CC1NC(=O)c2ccccc2NC1=O +COCC(O)CN(C)c1c(F)cc(C#N)cc1F +O=C1OCCC1Sc1nc(Cc2cccs2)n[nH]1 +CCCS(=O)(=O)NCC#Cc1ccc(C(N)=O)cc1 +Cc1ccc2ncc(C(=O)N(C)CCc3ccccn3)n2c1 +C=C(C)CN(CC)C(=O)c1ccc(=O)n(Cc2ccccc2)n1 +O=C(Cn1cccn1)N1CCCC(CO)(CCc2ccccc2)C1 +O=C(Nc1n[nH]c2c(Cl)cccc12)c1cnc(C2CCCO2)s1 +Cc1cc(C)c(C)c(S(=O)(=O)Oc2cccc(C(N)=O)c2)c1C +O=C(NC1CC1)c1nc2ccccc2nc1NC1CC1 +CC(C)CC(=O)Nc1nc(C(=O)NCc2ccncc2)cs1 +NC(=O)c1c(NC(=O)c2scnc2C2CC2)sc2c1CCCC2 +CC(Oc1ccc(Cl)cc1C(N)=O)C(=O)Nc1ccc(F)cc1 +CC(C)N(Cc1cnn(C)c1)C(=O)c1ccc(-n2cccn2)c(F)c1 +CC(C)CCOCCNc1c(N)ccc(F)c1F +COc1ccc(NC(=O)Cn2ncccc2=O)cc1OC +CC(=O)N1CCN(C(=O)Cc2cccc(F)c2)CC1 +CC(=O)c1cccc(S(=O)(=O)NCc2cscn2)c1 +CC1CN(C(C(=O)N2CCNCC2)c2ccncc2)CC(C)O1 +COCCCNC(=O)C1CCN(c2ncccc2-n2cccc2)CC1 +O=C(c1ccccc1)N1CC(c2nc(-c3ncccn3)no2)C1 +Cc1nc(NC(=O)NCCCc2nc(C(C)C)no2)oc1C +Nc1cccc2c1N(CC(=O)Nc1nccs1)CCO2 +CC(C)CC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1 +Cc1ccc2ncc(C(=O)OC(C)c3ccc(C#N)cc3)n2c1 +CCC(=O)N1CCc2cc(C(=O)N3CCCCCC3)ccc21 +CSc1ccc(NC(=O)Nc2ccc(C(C)=O)cc2)cc1 +Cc1cc(C2CCCN2Cc2ccc(C#N)cc2F)no1 +CCc1cccc(CC)c1NC(=O)C(C)n1cc(CO)nn1 +CCC(NC(=O)c1cn(C)c2ncccc12)c1ccc(OC)cc1 +COC(=O)Nc1ccc(OCC(=O)NCC2CCCCC2)cc1 +CC(=O)NC(C)C1NCCc2ccc(Br)cc21 +O=C(NC1CC(=O)N(CC2CCCCC2)C1)c1ccsc1 +CC(C)NC(=O)C(C)n1nc(-c2ccc(F)cc2)ccc1=O +CC(C)(C#N)C(=O)Nc1ccnc(Oc2ccccc2)c1 +Cc1cccc(Cn2nc(C)c(NC(=O)c3cccnc3)c2C)c1 +CCOC(=O)C(C)CNC(=O)N1C(C)CCCC1C +CCCNS(=O)(=O)c1ccc2oc(=O)ccc2c1 +CC(=O)Nc1ccc(C)c(NCc2ccc(OC(F)F)cc2)c1 +COC(=O)CC1CN(Cc2cc(C)c(C)cc2C)CCO1 +COCC(O)CN(C)C(=O)Cc1c(C)noc1C +CCn1cc(C2=NC(C(C)C)CO2)c2ccccc21 +Cc1ccc2c(c1)C(c1c(C)ncnc1C)NCC2 +Cc1ccc(NCc2c[nH]nc2-c2cccnc2)cc1 +Cc1ccc(NC(=O)N2CCCC2c2nc(C3CC3)no2)cc1 +O=C(Cc1nc2ccsc2c(=O)[nH]1)NC1CCCC1 +Cc1nc2ccc(CC(=O)N3CCN(CCO)CC3)cc2[nH]1 +CCN(C(=O)Cn1nnc(-c2cccc(OC)c2)n1)C1CCCCC1 +CCC(NC(=O)Nc1cnccc1C)c1cccc(S(N)(=O)=O)c1 +COCc1oc(-c2cc(F)ccc2F)cc1CO +O=C1Cc2cc(NC(=O)c3ccc(OCC(F)F)nc3)ccc2N1 +C#CCOc1ccc(Br)cc1CNCC(=O)NCC +NC(c1ccc(Cl)cc1)c1nnc2sc3c(n12)CCC3 +CCOc1ccc(C2=CCN(C(=O)COCC(F)(F)F)CC2)cc1 +CC(=O)Nc1cccc(OCC(=O)Nc2ccccc2)c1 +COCCCNC(=O)c1cc2c(=O)n3cccc(C)c3nc2n1C +CCc1cc(C(=O)NCc2c(F)cccc2OC(F)F)cc(=O)[nH]1 +O=C(Nc1c(F)cccc1F)c1ncn(-c2ccccc2)n1 +NC(=O)C1CCCN(C(=O)c2cccc3ccccc23)C1 +CC(CC#N)N(C)C(=O)c1cccc(-n2cccn2)n1 +CCCn1c(C)nnc1SCc1nnc(C)n1C +COC(=O)c1ccc(Cn2c(=O)[nH]c3cc(N)ccc32)cc1 +COCCn1cnnc1CCNc1nc(C)nc2c1c(C)nn2C +CCCCNC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +CC(NC(C)c1ccc(Cl)cc1Cl)C(=O)N(C)CCC#N +Cc1cc(C)n(CC(=O)n2c(C)c(C)c3ccccc32)n1 +CC(=O)Nc1cccc(-n2c(C)nnc2SCC2CCCCC2)c1 +Cc1noc(C)c1CCC(=O)N1CCN(Cc2ccsc2)CC1 +O=C(c1cc(=O)[nH]c2ccccc12)N1CC=C(c2ccccc2)CC1 +C#CCN(C(=O)c1cn2ccccc2n1)C1CCCCC1 +C=CCn1c(SCc2cccc(F)c2)nnc1C1CC1 +O=C(Cc1ccc[nH]1)NCC1CN(Cc2ccccc2)CCO1 +COc1ccc(C)cc1NCC(=O)c1cccs1 +Cc1ccc2ncc(C(=O)N3CCCC3c3ccccc3C)c(=O)n2c1 +CC(C)Cc1nnc(NC(=O)CN2CCc3cc(F)ccc3C2)s1 +CNC(=O)c1ccc(OC)c(NC(=O)c2cn(C)nc2C(C)(C)C)c1 +CCn1c(NCCCn2nc(C)cc2C)nc2c(C)nn(C)c2c1=O +O=C(Nc1ccccc1-n1cnnn1)C1CCCCC1 +CC(C)Nc1nnc(SCc2ccccn2)s1 +Cc1ccc2oc(=O)n(CCOc3ccccc3N)c2c1 +Cc1ccc2c(c1)C1(Nc3ccccc3C(=O)N1C1CC1)C(=O)N2 +N#Cc1ccc(-c2noc(CCc3c[nH]c4ccccc34)n2)nc1 +CC1CCCN(S(=O)(=O)N2CCCC(c3nncn3C)C2)C1 +NS(=O)(=O)c1ccccc1C(=O)Nc1ccc(Cl)cc1 +O=C(c1ccc(Cl)cc1)N1CCCC(C(=O)N2CCCCCC2)C1 +Cn1ccc(C(=O)NCc2nc3ccc(F)cc3[nH]2)cc1=O +C=C(c1ccccc1)c1nnc(-c2cccc(N)c2)o1 +CCOC(=O)CNS(=O)(=O)c1ccc(Cl)cc1F +O=C(Nc1n[nH]c2ccccc12)c1[nH]nc2c1CCC2 +CC(c1ccncc1)N(C)C(=O)NCCc1ccco1 +COc1ccc(CC(O)CC(F)(F)F)cc1Br +Cc1ccn(CCCC(=O)Nc2ccccc2N)c(=O)c1 +CCCC(CCC)C(=O)N1CCC(Oc2ccc(C)nc2)CC1 +CC(=O)c1ccccc1NC(=O)c1cccc(Oc2cnccn2)c1 +COC(=O)c1ccc(COC(=O)c2n[nH]c3ccccc23)cc1 +Cn1c(SCC(=O)Nc2cccc3ccccc23)nnc1C1CC1 +Cc1cccc(C(=O)Nc2ccc3c(C)cc(=O)[nH]c3c2)c1 +O=C(Nc1ccn(Cc2cccc3ccccc23)n1)C1CC1 +COc1ccc(N(C)C(=O)C2CN(C)CCO2)cc1Cl +O=C(NCCc1ccc(-n2cccn2)cc1)Nc1c(F)cccc1F +CCN(CC(=O)Nc1ccccc1C(F)(F)F)C(=O)c1ccoc1 +CCCN(C)c1ccc(C(=O)N2CCCC2c2ccc[nH]2)cc1 +CCSc1ccc(NC(=O)c2cnccn2)cn1 +COC(=O)c1cc(C)ccc1OCC(=O)NCc1ccccc1F +Cc1ccc(C)c(N2CCN(C(=O)NCc3ncn(C)n3)CC2)c1 +COc1ccc(F)cc1NC(=O)CC1CC2CCC1C2 +COc1cc(C(=O)Nc2ccc(C)cc2O)ccc1C +CCn1ncc(S(=O)(=O)Nc2nc3c(C)cccc3s2)c1C +CC(C)c1nc(CNc2cccc(OCC3CCCO3)c2)no1 +CCc1noc(C)c1NC(=O)c1cnn(CC(C)C)c1C1CC1 +FC(F)(F)CNCc1c[nH]nc1-c1cccs1 +CCOc1ccc(C2=CCN(C(=O)C3(C#N)CCC3)CC2)cc1 +CCCc1nnc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)s1 +Fc1ccc(OCC2CCCN(c3ccncn3)C2)cc1 +CCCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1F +CCc1nc2n(n1)CCCC2NS(=O)(=O)c1ccc(C#N)cc1 +CCOCC(=O)Nc1ccc(Br)cc1Cl +O=S(=O)(Cc1cccc(F)c1)c1ccc(F)c(F)c1 +Cn1ccc(-c2nnc(NC(=O)c3ccco3)o2)n1 +CCN(CCOc1ccccc1F)C(=O)c1ccc(N(C)C)cc1 +COC(=O)CC(NC(C)C)C(=O)c1ccc(F)c(F)c1 +CCc1cnc(CNC(=O)C2COc3ccc(F)cc3C2)s1 +O=C(CC1Sc2ccccc2NC1=O)Nc1nnc(C2CC2)s1 +O=C(NCCc1cc(Cl)cc(Cl)c1)c1cnn[nH]1 +Cc1ccc(OCCNS(=O)(=O)N2CCCCC2C)cc1 +Cc1oc(-c2ccco2)nc1Cn1c(-c2ccccn2)noc1=O +Cc1cc(F)ccc1C(=O)NCC(C)(C)c1ccncc1 +O=C(c1cccc(F)c1)N1CCC(c2nc3ccccc3o2)CC1 +COC(=O)c1ccc(-n2ncnc2-c2ccc(N(C)C)cc2)cc1 +COC(=O)C1=C(C)Nc2ncnn2C1c1ccccc1OC +CCc1ccccc1CNC(=O)NCC(C)(C)NS(C)(=O)=O +CSc1nnc(NCCc2cccs2)s1 +COCCOc1ccc(NC(=O)NC(C)C(C)C)cc1Cl +Cc1ccc(CNC(=O)COC(=O)c2cc(F)ccc2F)cc1 +CCC(O)Cn1nc(C)nc1Cc1csc(C(C)=O)c1 +COCc1cccc(C(=O)N(CCC(N)=O)c2ccccc2)c1 +Nc1cc(NC(=O)CC(F)(F)F)c(F)cc1F +Cc1ccc2cccc(OCC(=O)NCCc3ccc(F)cc3)c2n1 +N#Cc1nnn(Cc2ccc(F)cc2)c1-c1ccco1 +CCCC(C)(NC(=O)c1c[nH]c2cccc(F)c12)C(=O)OC +COC(=O)c1cc(S(=O)(=O)Nc2ccc(Cl)cc2F)c[nH]1 +Fc1cc(NCc2cc[nH]n2)ccc1-n1cncn1 +Cc1nnsc1C(=O)Nc1cc(N2CCCCC2)ncn1 +O=C(NCc1ccccn1)c1ccc(Oc2ccccc2)cc1 +CC(=O)NC(CC(=O)N1CCCC(C)C1)c1ccccc1 +O=C(NCc1cccc(NC(=O)C2CCCO2)c1)C1CC=CC1 +CC1Oc2ccc(N)cc2N=C1N1CCCc2ccccc21 +Nc1c(-c2cc(F)cc(F)c2)ncnc1N1CCCCC1 +Cc1nn(C)c(C)c1CNc1cc(Cl)cc(Cl)c1 +Cc1cccc(-c2[nH]ncc2CN2CCOC(C#N)C2)c1 +COCCNC(C)(C(=O)OC)c1ccc(Cl)cc1 +CNC(=O)c1cccc(NCc2cccc3cccnc23)c1C +O=C(NCCOc1ccc(C(F)(F)F)cn1)c1ccon1 +Cc1c(C(=O)OCc2ccccc2F)nnn1-c1ccc(F)cc1 +CCOc1ccc(CC(=O)N2CCN(C(C)=O)CC2)cc1 +CCc1ccc(CN(C(=O)NCC(=O)N2CCCCC2)C2CC2)cc1 +Cn1c(SCC(=O)NCc2cccs2)nnc1C1CC1 +CC(Sc1nc(N)cc(N)n1)C(=O)NCC(C)c1ccccc1 +CC#CCSc1nnc(C2CC2)n1-c1ccccc1 +COc1ccc(S(=O)(=O)Nc2cc(Cl)ccc2O)cc1 +CC(=O)Nc1c(C)nn(Cc2ccc(Br)cc2)c1C +COCC(=O)N1CCOC(c2ccc(C(F)(F)F)cc2)C1 +CCn1c(N2CCCC2)nc2c(C)nn(C)c2c1=O +O=C(NCc1ccccc1)NCc1cc(-c2ccccc2)on1 +Nc1cccc(C(Cc2cccnc2)C(=O)NC2CC2)c1 +CC(C)CCOc1cccc(-c2cc(C(N)=O)nc(N)n2)c1 +Cc1n[nH]c(CC2OCC3CN(C(=O)c4ccccn4)CCC32)n1 +O=C(NCCC(=O)N1CCCc2ccccc21)c1cc2ccoc2cn1 +CCOc1nn(CC)cc1C(=O)Nc1cccc(F)c1 +O=C(CCNC(=O)NC1CCCCC1)NCc1ccoc1 +COCc1nn(CC(=O)N(C)C2CCCCC2)c(=O)o1 +CCC(CC)C(=O)NC(C)c1ccc2c(c1)CC(=O)N2 +CCOc1ncccc1C(=O)Nc1n[nH]c(-c2ccc(OC)cc2)n1 +Cc1cc(NCC(O)CO)ccc1Br +O=C1c2cccnc2CN1CCS(=O)(=O)N1CCCC1 +Cn1ncc(Br)c1C(=O)NCc1ccc(Cl)cc1 +O=S(=O)(Oc1cccc(-n2cnnn2)c1)c1cccs1 +NC(=O)NCCC(=O)N1CCC(Oc2cccc(Cl)c2)C1 +O=C(c1ccc2ccccc2c1)N1CCc2ccccc2C1 +COc1ccc(C(=O)NC2CCCC(C)C2)cc1N +CN(C)C(=O)CN(C)c1cc(Br)ccc1CO +CCOc1ccccc1-c1cn2c(C)c(N)ccc2n1 +CN(C)c1cccc(C(=O)NCc2cc(-c3ccncc3)n(C)n2)c1 +Cc1cc(CN2CCN(C(=O)C3(C#N)CCCC3)CC2)no1 +O=C1CCC2(CCOC2)CN1Cc1csc(-c2ncccn2)n1 +CC1(NC(=O)C2CC(=O)N(Cc3ccccn3)C2)Cc2ccccc2C1 +Cc1c(C(C)C)c(=O)n(-c2ccc(S(N)(=O)=O)cc2)n1C +Cc1cccc(C(=O)NCCNC(=O)c2ccccc2O)c1O +CC(C)(C)NC(=O)c1nn(-c2ccccc2)c2c1CCC2 +Cc1nn(C)c(C)c1-c1cc(C(=O)NC(C)c2ccncc2)[nH]n1 +Cc1nc(-c2ccccc2Cl)sc1CNC(=O)c1cnccn1 +Cn1cnnc1-c1cccc(NC(=O)c2ccccn2)c1 +Cc1cccc(OCCCC(=O)Nc2ccc(S(C)(=O)=O)cc2)c1 +CC(C(=O)NCC(=O)Nc1ccc(-n2cncn2)cc1)C(C)(C)C +CCC(CC)C(CNC(=O)c1ccc[nH]1)N1CCOCC1 +CC(NS(=O)(=O)c1ccc(C(N)=O)cc1)c1ccccn1 +CCC(=O)N1CCCN(C(=O)Nc2cc(Cl)ccc2OC)CC1 +O=C(NCc1cccc(F)c1)c1cc(Sc2ncccn2)ccn1 +Nc1ccccc1NC(=O)CCCn1cc(Br)cn1 +Cc1ccc(SCCCN(C)C(=O)c2cc(C3CC3)[nH]n2)cc1 +N#Cc1ccc2nc(Cc3ccc(Cl)cc3)nn2c1 +O=C(Nc1ccccc1C(=O)NC1CC1)c1ccc(Cl)cc1 +O=C(Cc1ccc(F)c(F)c1)N1CCN(C(=O)c2ccco2)CC1 +CC(=O)NC1CCCN(c2nnc(-c3cccc(F)c3)cc2C)C1 +COCc1cccc(S(=O)(=O)NC(C)c2ccncc2)c1 +CC(=O)N1CCN(C(=O)C2(C)Oc3ccc(C)cc3NC2=O)CC1 +CC1=C(C(=O)N2CCOCC2)C(c2cccc(O)c2)n2ncnc2N1 +COc1ccc(-c2noc(C(=O)NCc3ccccn3)n2)cc1OC +CCC(CC(O)C(C)(C)C)NS(=O)C(C)(C)C +CC(OCC1CCCO1)C(=O)C(C#N)c1nc2ccccc2o1 +CCc1ccc(CNc2cccc(C(=O)NC3CC3)c2)o1 +Cc1cc(C(=O)Nc2ccc(-c3cnc(C)o3)cc2)[nH]n1 +CCN(c1ccccc1)S(=O)(=O)c1ccc2c(c1)C(C)(C)C(=O)N2 +CC1(C)C2OCCC2C1OC(=O)c1cc(C2CC2)[nH]n1 +CN1C(=O)COc2ccc(-c3cc(=O)[nH]c(N)n3)cc21 +Cc1noc(C)c1CCC(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +Cn1c(Cn2cncn2)nnc1C1CCN(c2ncccc2F)CC1 +Cn1c(SCc2coc(-c3ccccc3)n2)nnc1-c1ccncc1 +COc1ccc2c(c1)CCc1c(C(=O)NCCc3c[nH]cn3)n[nH]c1-2 +N#CC(C(=O)c1occc1-c1ccccc1)c1ccccn1 +Cc1ccccc1C1(CNC(=O)c2ccc[nH]2)CCOCC1 +CCOc1cc(S(=O)(=O)N(CC)CC)ccc1F +O=C1OC(C(=O)Oc2ccccc2)Cc2ccccc21 +CCOc1ccc(C(=O)N(CCC#N)CCC#N)cn1 +Cc1c(C(=O)N2CCC3(CC2)OCCO3)cnn1-c1ccncc1 +O=C(Nc1ccc2[nH]nnc2c1)c1ccnc(OC2CCC2)c1 +O=C(NCCNC(=O)c1cccnc1)NCc1ccccn1 +COc1ccc(NC(=O)N(C)Cc2nc3ccccc3s2)cc1F +CCCNC(=O)c1cccc(NC(=O)c2nnc(COC)s2)c1 +COc1cc(F)c(C(=O)Nc2cc(C)cc3cccnc23)cc1OC +CCOC(=O)Cc1nnc(NC(=O)Nc2cccc(Cl)c2)s1 +CC(C)c1ccccc1NCC(=O)Nc1cccc(C(N)=O)c1 +O=C(NCCn1nc(-c2ccncc2)c2c1CCCC2)C1CCC1 +O=C(NCCn1nnc2ccccc21)Nc1nc[nH]n1 +CC=Cc1ccc(OCC(=O)Nc2c(C)nn(C)c2C)c(OC)c1 +COC(=O)C1(NC(=O)c2cccc(-c3ccoc3)c2)CCC1 +Cc1noc(C(C)NC(=O)c2ccccc2N2CCCCC2)n1 +CC(C)(C)CCNC(=O)CN1CCOCC1C1CC1 +COc1ccccc1C(=O)Nc1nc(-c2ccccn2)cs1 +Oc1cc(Cl)c2c(c1)C(c1ncccn1)NCC2 +CCc1nc2cc(Cl)cnc2n1Cc1ccccc1C#N +COCCOc1cccc(CNC(=O)c2cnn[nH]2)c1 +CC(=O)c1nnc(-c2ccccc2)n1Nc1ccccc1 +CNC(=O)c1cnc(-c2ccccc2)nc1CCNC(=O)COC +Cc1ccsc1CN(C)C(=O)c1cccc(C#N)c1 +COC(=O)c1ccc(CSc2nc3ccsc3c(=O)n2C)o1 +OCC1CCN(c2ccc(Br)cn2)CC1 +Cc1nc(N2CCOc3c(O)cc(-c4ccc(C)s4)cc3C2)no1 +C=CCn1c(=O)c2c(nc3n2CCS3)n(C)c1=O +CCOc1ccc2c(c1)c1nnc(SCC(=O)OC)nc1n2C +CCOc1ccc(OCCn2nc(C)c(C)c(C#N)c2=O)cc1 +CCNC(=O)c1ccc(NC(=O)c2cc(C)no2)c(C)c1 +COc1cccc(OC)c1C(=O)NCc1cccnc1 +O=C(NCc1nnc2n1CCC2)C1CC1c1cccc(F)c1F +O=C(Nc1ccccc1)C1CCN(C(=O)Cc2ccccc2F)CC1 +CC(O)CNC(=O)c1ccc(Oc2ccc(C(F)(F)F)cn2)cc1 +C#CCNC(=O)c1nccnc1C(=O)NCc1ccc(F)cc1 +COC(=O)C1CCCCN1Cc1cccc2c1OCCCO2 +CCC(CC)NC(=O)C12CCC(=O)N1c1ccccc1S2 +CSc1ccc(NC(=O)N2CCOCC2C2CC2)cc1F +COCC(=O)Nc1ccc(NC2CCOCC2)cc1 +CC(=O)Nc1cc(NC(=O)NCC2CC2)c(F)cc1F +CCC(CC)C(=O)Nc1ccc2c(c1)C(=O)N(C)C1=NCCN12 +Cc1ccc(C)c(OC(=O)CCSc2nnnn2C)c1C +CCC(=O)c1ccc(OC(=O)Cc2csc(C)n2)cc1 +O=C(c1ccccn1)N1CCc2ccc(Cl)cc21 +CCNC(=O)c1ccc(C)c(NC(=O)NC2C3CCC(C3)C2CO)c1 +CCS(=O)(=O)Nc1ccc(C)cc1Br +COc1ccc(N(C)C(=O)c2cc(C)ccc2N2CCCC2=O)cn1 +CCOC(=O)NC1CCCN(C(=O)c2cnns2)C1 +CCOC(C)c1nc(Cn2ccc(-c3ccccc3)n2)cs1 +CCCc1ccc(-c2cc(NC(=O)c3cnccn3)[nH]n2)cc1 +COC(=O)c1cccc(C2NCCc3c(O)cccc32)c1 +COc1c(F)ccc2c1CCNC2c1ccc(F)cn1 +NC(=O)NCCC(=O)NCCc1cccc(F)c1 +COc1cccc(OCCNC(=O)c2cccc(OC)c2)c1 +COc1ccc(N)cc1NC(=O)c1ccc(O)c(Cl)c1 +CCc1ccc(OC2CNC(C(=O)OC)C2)c(Br)c1 +Cc1ccc(S(=O)(=O)N(C(C)C)C(C)C)cc1 +COC(=O)CNC(=O)Nc1ccccc1-c1cc2ccccc2[nH]1 +COc1ccc(NC(=O)CCC(=O)c2ccc(F)cc2F)cc1F +N#Cc1ccc(F)c(C2NCCc3ccc(F)cc32)c1 +NC(=O)NCc1ccc(C(=O)NCc2cccc(F)c2)cc1 +COCCN(Cc1ccccc1)C(=O)c1cc(Cl)c2c(c1)OCO2 +N#Cc1nnn(-c2cccc(C(F)(F)F)c2)c1-c1ccncc1 +O=C(Nc1ccc2c(c1)N(C(=O)C1CC1)CC2)c1ccc(F)cc1F +COCCN(C)C(=O)CNS(=O)(=O)c1cnn(C)c1 +Cc1ccc(-c2n[nH]c(CCc3ccccc3)n2)cc1N +CCC(CC)(C(=O)Nc1nccn(C)c1=O)c1ccc(Cl)cc1 +Cc1cnc(C(=O)NCc2cccc(COC(C)C)c2)cn1 +CC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccc(C)o2)cc1 +CCS(=O)(=O)c1ccc(NCC(=O)N(C)C)cc1 +CC(C)c1nc(CN(C)Cc2cccnc2)cs1 +O=C(Nc1nc2ccccc2s1)C1CC(=O)N(C2CCCC2)C1 +Cc1noc(C)c1CNc1ccc(OCCO)nc1 +CCN(Cc1ccccc1)C(=O)c1cc2sccn2c1 +COc1ccccc1N(CC(N)=O)S(=O)(=O)c1ccccc1 +CCN(Cc1cccc(Cl)c1)c1ccc2nnnn2n1 +O=C(c1ccn(-c2ccccc2)n1)N1CCc2sccc2C1 +C=C(C)CSc1nnc(SCC(N)=O)s1 +CCNC(=O)c1cccc(NC(=O)CNc2cc(OC)ccc2F)c1 +O=C(NCC(F)(F)F)c1c[nH]nc1C1CCCCC1 +Cc1nc(CC(=O)NCCc2ccc(F)cc2)cs1 +CC(C)(C)C(=O)NCC(=O)NC1CCN(c2c(F)cccc2F)C1 +CCNc1nnc(-c2cccn(CCCOC)c2=O)s1 +COc1ccc(-c2nn(CC(N)=O)c(=O)c3nc(C)sc23)cc1 +NS(=O)(=O)c1ccc(NCc2ccccc2)cc1C(F)(F)F +CC(C)c1ccc(CCNC(=O)Cn2cc(Cl)c(=O)[nH]c2=O)cc1 +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1ccccc1OCC1CC1 +COc1cccc(OCCNC(=O)N(C)Cc2cc(C)on2)c1 +N#Cc1cnc(N2CCC(c3ccc4ccccc4c3)C(O)C2)nc1N +Cc1nc(-c2ccc(NCC(O)c3ccco3)nc2)[nH]c(=O)c1C +C=CCSc1nnc(C2CC2)n1-c1ccccc1 +CN(C)c1ccccc1C#CCNC(=O)C1CC=CCC1 +O=C(CCc1ccncc1)N1CCC(CSc2ccccc2)C1 +Cc1ccc2ncc(C(=O)N3CCCC4(CC=CCC4)C3)n2c1 +CCC1CCC(C)N1C(=O)c1sc(NC(=O)C2CC2)cc1C +O=C(Cc1ccc(-n2cnnn2)cc1)NCC1COc2ccccc2C1 +O=C(Cc1c[nH]c2ccccc12)Oc1ccccc1F +Cc1ccnn1-c1cccc(NC(=O)NCC(C)(O)c2ccco2)c1 +Cc1cc(O)c(C(C)C)cc1NC(=O)C(C)NC(=O)c1ccoc1 +CC(Cc1cnccn1)NC(=O)c1ccc2c(c1)OCCO2 +CCS(=O)(=O)NCCCOc1ccc(F)cc1 +Cc1nc2ccccc2n1CCCOC(=O)c1cc(C(N)=O)cn1C +CC(C)Oc1nn(-c2cccc3c2OCC3)c(=O)o1 +NC(=O)C1CCCN(C(=O)COCc2ccccc2Cl)C1 +CC(C)Oc1ccc(CNC(=O)C2COc3ccccc3O2)cc1 +COc1cccc(CN2CCOC(c3ccc(F)c(F)c3)C2)c1OC +COC(=O)Nc1nc2c(OC)c(OC)c(OC)cc2[nH]1 +CN(C)c1ccc(C(=O)OCc2nccn2C)c(F)c1 +O=C(NCC1CC1)Nc1cccc(-c2cn[nH]c2)c1 +CCC(C)(C#N)NC(=O)c1cccc(Br)c1 +CCOC(=O)CCCC(=O)c1ccc(F)c(F)c1 +Cc1nn(C)c(C)c1CCC(=O)NCc1cnn(C)c1 +Cc1nnnn1-c1cccc(NCc2cccn2C)c1 +CC(=O)N1CCC(NC(=O)NCC2Cc3ccccc3O2)CC1 +O=C(NCCNC(=O)C1CC1)NCC1(c2ccc(F)cc2)CC1 +Cc1ccc(C(=O)N(C)Cc2ccccn2)cc1O +CC(C)(C)N1CC(C2NCCc3cc(F)ccc32)CC1=O +N#Cc1csc(CNc2ccc(F)cc2OC(F)F)c1 +COC(=O)c1ccc(Cl)c(NC(=O)c2sc(C)nc2C)c1 +COC(=O)C1C(=O)c2c([nH]c(C(=O)OC(C)C)c2C)CC1C +CC(=O)c1ccc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)cc1 +CC(C)OCCC(=O)Oc1ccc(-n2cnnn2)cc1 +Cc1ccc(C)c(Cn2ccnc2CN(CC2CC2)C(=O)C2CC2)c1 +O=S(=O)(Nc1cn[nH]c1)c1c(Cl)cccc1Cl +N#CC1Cn2c(nc3c(c2=O)C2(CCCC2)Cc2ccccc2-3)S1 +Cc1nn(C)c(C)c1C(C)NC(=O)c1ccccc1Br +CCOc1ccccc1C(=O)Nn1c(C)cc(C)cc1=O +Cc1csc(CN2C(C)COC(c3ccccc3)C2C)n1 +Cc1ccc(F)c(NC(=O)c2cnc(C3CCCO3)s2)c1 +Cc1cnc(C(=O)Nc2ccc(Cl)c3cccnc23)cn1 +CC(OCc1ccccc1)C(=O)N1CCCC(c2nncn2C)C1 +Cc1ccccc1NC(=O)CCCN(C)C(=O)OC(C)(C)C +COc1ccc(CCc2ccc3c(c2)OCO3)cc1O +O=C(CSc1ccncn1)Nc1ccc(F)cc1 +COc1ccc(C(C)=O)cc1Cc1nc(-c2ccc(C#N)cn2)no1 +O=S(=O)(NCCCN1CCOCC1)c1ccc(F)c(F)c1F +CCC(CC)N(CCO)C(=O)c1cc(N)ccc1C +CC(=O)N1CCC(NC(=O)C(O)c2ccccc2)c2ccccc21 +Cc1cc(C)n(CC(=O)N2CCC3(CN(C)C(=O)O3)C2)c(=O)n1 +CC(C)(C)n1nc(C2CC2)cc1C(=O)NCC1(C(N)=O)CCOCC1 +CCOc1ccc(NC(=O)CN2CCCCC2=O)c(C)c1 +COc1ccccc1CNC(=O)CS(=O)(=O)c1nccn1C +CCOC(=O)Nc1nnc(COc2ccc(Cl)cc2)s1 +Cc1cccc(NC(=O)CCCOc2ccccc2F)n1 +Cc1ccncc1NC(=O)NC(C)c1ccc(-c2ccncc2)cc1 +Brc1cccc(Cc2nc(-c3ccncc3)no2)c1 +COc1ccc(C(=O)NC(CO)c2ccccc2)cc1OC +COc1ccc(CCC(=O)N2CCN(C(=O)CO)CC2)cc1 +CCCNC(=O)CCNc1nc2ccccc2nc1C +Cc1cccc(NC(=O)c2nccc3c(F)ccc(N)c23)n1 +COC(=O)C(Nc1ccccc1Br)c1cnn(C)c1 +Cc1cc(C)cc(NC(=O)NCc2ccc(S(C)(=O)=O)cc2)c1 +COc1ccccc1C1CNC(=O)c2nc(-c3ccnc(C)c3)[nH]c2C1 +COc1cc(-c2ccccc2)nn2c(CO)nnc12 +O=C(Cc1ccc(F)cc1F)N1CCOC(c2ccccc2F)C1 +CCCCNC(=O)c1ccccc1NC(=O)c1cccs1 +CCCC(=O)N1CCOC(c2noc(-c3ccc(OC)cc3)n2)C1 +COc1cc(NC(=O)C2C(C=C(C)C)C2(C)C)c(C(N)=O)cc1OC +Cn1cccc1CNc1cc(Cl)cc2cccnc12 +CC(C)c1ncc(Cl)c(C(=O)NC2CCCNC2=O)n1 +CCS(=O)(=O)NC1CCN(C(=O)c2ccncc2)CC1 +CCN(CCC#N)c1ccc(N)c(OCC2CC2)n1 +CC(C)NC(=O)NCCCCN(C)c1ccccc1 +Cc1cc(C)n(-c2cc(NCc3ccc4c(c3)OCO4)ncn2)n1 +Cc1cnc2c(c1)nc(-c1ccccc1Cl)n2CCO +CNC(=O)CN1CCN(c2cccc(C)c2C)CC1 +COc1ccc(NC(=O)C2CCCCC2)cc1-n1nnnc1C +CCOC(=O)c1nnn(-c2ccc(C(C)C)cc2)c1C +C#Cc1cccc(NC(=O)CNC(=O)CCc2ccc(F)c(F)c2)c1 +CCC(CC)c1cc(CNC(=O)c2c[nH]c3cccc(F)c23)on1 +CCOC(=O)c1scc(S(=O)(=O)c2ccc(C)cc2)c1N +O=C1CN(c2nccc(CCC(F)(F)F)n2)CCN1C1CCCC1 +O=C(c1cccs1)N1CCC2C(CCC(=O)N2CCCCO)C1 +O=C(Cc1ccon1)Nc1cnn(-c2ccccc2Br)c1 +Cc1cc(NC(=O)CSc2nnc(-c3cccnc3)n2N)no1 +Cc1cccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c1C +CC(C)N(Cc1ccccc1)C(=O)C1CN(C(=O)c2cccs2)C1 +COC(=O)C(C)n1c(CCO)nc2cc(O)ccc21 +CCC(CC)C(=O)Nc1ccc(C)c(N2CCCC2=O)c1 +COc1cc(C(=O)NCC(O)COc2cccc(C)c2)ccc1C +CC(C)CC(=O)NC(C(=O)Nc1nc(C(C)C)cs1)C(C)C +O=C(Cn1cnc2c(sc3ncccc32)c1=O)Nc1nccs1 +Cc1cnn(C(C)C2CC2)c1NC(=O)c1ccc2nc(C)c(C)nc2c1 +Cc1cccc(C)c1NCC(=O)Nc1ccccc1 +CCOC(=O)CN(C(=O)CC1C=CCC1)C1CC1 +O=C(NC1CCCCC1)c1cc(F)cc2[nH]cnc12 +CCOCCOc1cccc(NC(=O)N2CCC(O)C2)c1 +Cc1cc(C)n2c(SCc3ccccc3)nnc2n1 +C#CCNC(=O)CSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1 +CCn1nc(C)c(NCc2cnc(CC(C)C)s2)c1C +CCn1cc(NC(=O)C2CCC(=O)N(C)C2c2ccccc2)cn1 +CC(C)(NC(=O)C1OCCc2ccccc21)C(=O)Nc1ccccc1 +OCCn1nc(-c2ccccc2F)c2c1CCNC2 +COc1ccc(-n2nnnc2C=CN2CCOCC2)cc1 +CC(C)Oc1ccc(C(=O)N(CC(N)=O)C2CCCC2)cn1 +N#Cc1ncc(Br)c2c(N)ccc(Cl)c12 +CC(C)NC(=O)N1CCN(Cc2cc3ccccn3n2)CC1 +NC(=O)c1cccc(C(=O)NCc2cn3ccccc3n2)c1 +O=C(OCc1ccccc1F)c1n[nH]c(=O)c2ccccc12 +Cc1cc(C)c(C)c(S(=O)(=O)NC(C)(C)C(=O)N(C)C)c1C +COC(=O)c1cc(-c2cc3cccc(OC)c3o2)nn1CCO +COCc1ccc(CNC(=O)NCCc2ccc(F)cc2C)cc1 +CC(C)OCCOC(C)C(=O)Nc1cc(N)ccc1F +O=C(Nc1ccccc1)C1CCN(c2ccc(-c3ccco3)nn2)CC1 +CCCc1cc(C(=O)NC2CCN(c3c(F)cccc3F)C2=O)[nH]n1 +CC(C)c1cc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)n[nH]1 +COc1cccc(C(=O)NCC(O)c2ccsc2)c1 +COc1cccc(-n2cnnc2-c2nc(-c3cccnc3)cnc2N)c1 +CC(C)CN(CC(F)(F)F)C(=O)c1ccccc1N +O=C(Nc1ccc2c(c1)OCCO2)C1CCN(c2cnccn2)CC1 +O=C(CCc1n[nH]c2c1CCCC2)NCCc1ccc2c(c1)OCO2 +CC(C)c1[nH]ncc1C(=O)OCc1cc(Cl)c2c(c1)OCO2 +CS(=O)(=O)c1ccccc1NC(=O)NC1CCc2ccccc2C1 +O=C(NCC1(c2ccccc2)CC1)C1CC2CCC1O2 +CCCCS(=O)(=O)N1CCC(C(=O)OC)(c2ccccc2)CC1 +Cc1cc(NC(=O)c2cc3c(Cl)cccc3n2C)no1 +N#Cc1ccc(OCC(=O)NC2CCCCCC2)cc1 +Clc1ccc2nc(CNc3ccccc3-n3cccn3)cn2c1 +Cc1cc(NC(=O)c2cn(C)c3ccccc23)[nH]n1 +CCC(C)(NC(=O)c1ccncc1F)c1ccccc1 +CC1CN(C(=O)c2cc(-c3ccccc3)nc3ccccc23)CCO1 +COc1cccc(COc2cc3c(cc2N)OCCO3)c1 +Cc1cnc(NC(=O)c2cc3ccccc3o2)s1 +COc1ccc(-c2nc3ccc(C)nc3o2)cc1OC +COc1ccc(Cl)cc1NCc1nnc(-c2ccc(F)cc2)o1 +COC(=O)c1cc2occc2n1CC(=O)Nc1cccc(SC)c1 +Cc1noc(COCC(=O)N2CC(C)(C)Sc3ccccc32)n1 +CC(=O)c1cnc(NC(=O)c2nc(N3CCCC3)ncc2Cl)o1 +C=C(C)C1CC=C(COC(=O)CCc2nc(C)no2)CC1 +COc1ccc(Br)c(C(=O)NC(C)C(C)C)c1 +CC(C)Cc1nnc(NC(=O)c2ccc3c(c2)OCC(=O)N3)s1 +N#Cc1nnn(Cc2c(F)cccc2Cl)c1C1CCCO1 +CC(NC(=O)Cc1cnn(-c2ccccc2)c1)c1ccccc1 +CCc1ccccc1NC(=O)COc1cccc(NC(=O)OC)c1 +COC(=O)c1cccc(NC(=O)c2cc(-c3ccccc3)no2)c1O +O=c1c(Cl)c(Br)cnn1-c1ccccc1 +CNc1ccc(NS(=O)(=O)c2ccccc2)c(F)c1 +COC(=O)C1CCCN1C(=O)C(C)NC(=O)OC(C)(C)C +COCCNC(=O)N1CCN(CC(=O)N2CCCCCC2)CC1 +COCCN(Cc1c(C)nn(C)c1C)C(=O)Nc1cccc(C)c1 +CCOC(=O)Nc1cccc(C(=O)Nc2ccc(C(C)=O)cc2)c1 +OC(CCC1OCCO1)c1ccc2c(c1)OCO2 +CC1CCN(C(=O)NCc2cccc(CN3CCCC3=O)c2)CC1 +CCN(C(=O)c1ccc2c(c1)OCC(=O)N2)c1cc(C)cc(C)c1 +O=C(NCCN1CCN(C(=O)C2CC3CCC2C3)CC1)C1CCC1 +CC(=O)Nc1cc(C(=O)N(C)CC2CCCO2)ccc1F +COC(=O)C(OC(=O)c1cccc(-n2cncn2)c1)c1cccnc1 +CC(NC(=O)CCNC(=O)c1ccco1)C12CC3CC(CC(C3)C1)C2 +CC(C)NC(=O)C1CCN(C(=O)C2Cc3ccccc3C(=O)O2)CC1 +CCCC(=O)N1CCCCC1C(=O)Nc1ccc(F)c(C(N)=O)c1 +CC1CN(C(=O)c2ccncc2)CCC1(O)C1CCOCC1 +COC(=O)CCCC(=O)N1CCOC(Cc2cccc(F)c2)C1 +CCn1nccc1C(=O)N1CCC(c2cc3c(C)cccc3cn2)CC1 +CNC(=O)c1nn(C)cc1NC(=O)c1ccccc1Cl +COc1ccc2c(=O)cc(C(=O)NCc3nc4ccccc4[nH]3)oc2c1 +COC(=O)c1ccc(OCC(=O)Nc2cc(C)ccn2)cc1 +CC(C)c1cc(C(=O)N2CCCCC2C)c2cnn(C(C)C)c2n1 +CC(=O)c1ccccc1NC(=O)c1ccc(-n2cnnn2)cc1 +CCNC(=O)CSc1nc2ccc(OCC)cc2[nH]1 +CN(Cc1nc2ccccc2[nH]1)C(=O)c1ccc2[nH]cnc2c1 +CC(=O)c1ccc(S(=O)(=O)N(CCc2cccs2)C2CC2)cc1 +CC(C)(CNC(=O)CNC(=O)c1ccc(F)c(F)c1)c1ccncc1 +O=C(NCC(=O)N1CCC(Oc2cccnn2)CC1)c1ccccc1 +CCCN(C(=O)NCc1nnc2n1CCC2)C1C2CCOC2C1(C)C +Cc1ccc(C(=O)CNC(=O)c2ccccc2)cc1 +COc1ccc(CS(=O)c2nc[nH]n2)cc1F +Cc1nc2cc(CC(=O)NCc3ccc4c(c3)OCO4)ccc2[nH]1 +Cc1ccc(C)c(OCC(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)c1 +O=C(CCC(=O)N1CCCC1C1CCCCC1)N1CCOCC1 +CC(=O)NC(C)C(=O)N(Cc1cccc(F)c1)C1CC1 +COc1ccccc1NC(=O)C1CCN(S(N)(=O)=O)CC1 +C=CCn1nnnc1SC(C)C(=O)Nc1cccc(C#N)c1 +CN(C(=O)CNc1ccn(-c2ncccc2Cl)n1)C1CC1 +Cc1ccnc(OCC23COCC2CN(C(=O)c2ccnnc2)C3)n1 +CCOC(=O)CN(C)C(=O)c1cc(N)ccc1C +CCCn1c(=O)c2nscc2n(CC(=O)N2CCCC2)c1=O +CCn1cc(C(=O)N(C)S(=O)(=O)C(C)C)cn1 +CN(Cc1csc(-c2ccoc2)n1)C(C(N)=O)c1cccc(F)c1 +CCc1ccc(NC(=O)c2ccc(C)nc2N)cc1 +CC(Sc1nncs1)C(=O)N1CCCC1c1ccc[nH]1 +CCCNC(=O)c1cc(F)c(Cl)cc1Cl +Cc1oc(-c2ccccc2Cl)cc1C(=O)N1CC(C)OC(C)C1 +O=S(=O)(c1cccc2cccc(Cl)c12)N1CCOCC1 +Cc1nnn2c(C(=O)Nc3cnc4ccccc4c3)cccc12 +CCC(C)NC(=O)CNc1cccc(C(=O)NC(C)C)c1 +O=C(c1ccnc2ccccc12)N1CCC(Nc2ccccc2)C1 +Cc1ccc(-n2nnnc2SCC(=O)N2CCC(C)CC2)cc1 +CN(C)c1cccc(CNC(=O)Nc2ccc3c(c2)COC3)c1 +COc1ccc(OC)c(CC(C#N)C(=O)N(C)C)c1 +CCOCCOc1c(Cl)cccc1NC(=O)C1CCC(=O)N1 +Cc1ccc(SCCC(=O)N2CCC(c3nc(C)no3)CC2)cc1 +Cc1nnc(CN(Cc2cn3cc(Cl)ccc3n2)C(C)(C)C)o1 +CCNC(=O)C1CCCN(C(=O)Nc2cccn(C)c2=O)C1 +CCC(CC1CCCC1)C(=O)NCCc1nc(C)no1 +N#CCCC(C#N)CSc1ncnc2c1cnn2-c1ccccc1 +CNC(=O)c1cccc(NCC(=O)NC2(C#N)CCCC2)c1C +Cc1ccc(C)c(CNC(=O)c2ccc3c(c2)CC(=O)N3C)c1 +Brc1cccc2[nH]c(-c3cccnc3)nc12 +CCCCOc1ccc(OC)cc1NC(=O)N1CCOCC1 +CC(C)(C)C(=O)Nc1cccc(CN2CCCCC2=O)c1 +COc1ccc(CC(C)C(=O)Nc2cncnc2N(C)C)cc1 +Cc1nc(OCCNC(=O)C2CCCC2)cc(N2CCCC2)n1 +COC(=O)c1c(C)[nH]c(C(=O)COc2ccc3c(c2)OCCO3)c1C +CN(Cc1nccs1)Cc1ccccc1OCc1cccnc1 +CCC(=O)Nc1cccc(NC(=O)NCc2csc(NC)n2)c1 +CCOc1cc2c(cc1CNC(=O)c1cc(C)sc1C)OC(C)C2 +CCc1ccccc1NC(=O)COc1cccc(N2CCCC2=O)c1 +Cc1ccc(OCCCn2cnc(C3CCC3)cc2=O)cc1C +CS(=O)(=O)c1ccc(-c2ncccc2C(=O)N2CCCCC2)cc1 +COC(=O)c1cccc(S(=O)(=O)NCCc2cnn(C)c2)c1 +CCN(Cc1ccc2c(c1)OCCO2)C(=O)c1ccc(N(C)C)nc1 +NC(=O)c1cccc(NC(=O)CNc2cccc(Cl)c2Cl)c1 +CC(CN1CCOCC1)NS(=O)(=O)c1ccc(C(N)=O)cc1 +Cc1cc(NC(=O)c2c[nH]c3cccc(F)c23)n(Cc2ccccc2)n1 +NC(=O)c1cccc(NC(=O)COc2ccccc2Cl)c1 +CSc1ccccc1C(=O)Nc1ccc2c(c1)C(=O)NCC2 +O=C(Nc1cccc(-c2cscn2)c1)c1n[nH]c2ccccc12 +Cc1nc(C(C)C)sc1C(=O)N1CC(C)OC(C)C1 +Cc1ccc(CC(=O)NCC(c2cccs2)N2CCOCC2)cc1 +Cc1ccc(OC2CCN(C(=O)CC(C)(C)C)CC2)cn1 +Cc1oc2cc3oc(=O)c4c(c3cc2c1C)CCC4 +CCC(C#N)NC(=O)CCCOc1ccccc1F +CC(=O)NCCCSc1nccn1Cc1ccccn1 +CC(OC(=O)c1ccc(-c2cccc(C(F)(F)F)c2)o1)C(N)=O +Cc1ccc(NC(=O)CC2CCCC2)cc1N1CCCC1=O +Cc1occc1CN(C)C(=O)NCc1ccc(F)cc1 +O=C(CSc1nccn1Cc1ccccc1)N1CCOCC1 +Cc1nn(C)cc1-c1[nH]c(CC(C)(C)C)nc1C#N +CSc1cncc(N(C)CCc2ccccn2)n1 +CCc1noc(C2CC(=O)N(c3cccc(Cl)c3)C2)n1 +O=C(Nc1ccc(-n2nccn2)cc1)c1ccc(OCC(F)F)nc1 +OCc1nnn(-c2ccccc2)c1-c1ccc(Cl)cc1 +COC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(OC)cc2)cc1 +COC(=O)NC(C(=O)NCc1ccccc1CO)C(C)C +O=C(Nc1ccnc2ccccc12)c1ccc(-n2cnnn2)cc1 +Cn1nc(C(=O)Nc2nnc(Cc3ccccc3)s2)ccc1=O +O=C(NC1CCOCC1)C1Cc2ccccc2CN1 +Cc1cncc(C(=O)N2CCC(Cc3cccc(C(N)=O)c3)C2)c1 +C=CCn1c(SCc2nnc(C(C)C)o2)nnc1C(F)(F)F +COc1ccc(NC(=O)c2n[nH]c(=O)c3ccccc23)c2cccnc12 +CCOC(=O)C1CCCN(c2nccc(OC)n2)C1 +O=C(C1CC1)N1CCC(c2nc(CCCc3ccccc3)no2)CC1 +COc1cccc(C(=O)NCC(=O)N2CCc3sccc3C2)c1 +Cc1cc(C(=O)N(C)C(C)c2ccc(F)c(F)c2)no1 +Cc1sc2ncn(CCC(=O)NCC(N)=O)c(=O)c2c1C +CCc1nnc2n1CC(NC(=O)c1ccc3c(c1)CCCC3)CC2 +Cc1ccc(S(=O)(=O)N2CCN=C2N2CCOCC2)cc1 +COc1ccc2c(c1)nc(C#N)n2Cc1ccc(N)nc1 +N#Cc1cc(S(=O)(=O)N(CCO)CCO)ccc1Cl +COc1ccnc(N(C)Cc2cnn(Cc3ccccc3)c2)n1 +CC(OC(=O)c1cccnc1)C(=O)N1CCc2ccccc21 +CCOc1ccc(NC(=O)C(C)(C)C)cc1OCC +CCCC(=O)Nc1c(C)cc(C(=O)OC)cc1N +O=C(NCCCO)c1coc(-c2ccc(Br)cc2F)n1 +Cc1nc2cc(NC(=O)CCc3c(C)noc3C)ccc2o1 +Cc1ccccc1CNc1nc(N2CCOCC2)nc2c1cnn2C +O=C(NCCNC(=O)c1cc(Br)c[nH]1)c1ccoc1 +CCCNC(=O)c1ccccc1NC(=O)c1ccoc1C +CC(C)C(=O)N1CCC(c2nnc(-c3ccco3)o2)CC1 +CN(Cc1ccccc1)C(=O)c1cccc(NC(=O)C(C)(C)C)c1 +O=C(NCCc1nc(-c2ccccn2)no1)c1ccsc1 +CC(C)N1CCOC2C(OCc3ccncc3)CCC21 +Oc1cc(O)c2c(c1)C(C1COc3ccccc3O1)NCC2 +Cc1ccc(C(N)C(=O)NCC2CCCO2)cc1C +O=C(NCc1cccnc1)C(Cc1ccccc1)n1cnnn1 +Cc1cc(C)cc(C2CCN(C(=O)c3cccnc3)C2)c1 +COc1ccc2c(CC(=O)Nc3ccn(C)n3)coc2c1 +O=C(C1CCOC1)N1CCCCC1c1nccs1 +Cc1ccc(NC(=O)c2c[nH]c3ccc(Cl)cc3c2=O)cc1 +Cc1nc(-c2ccc(F)c(Br)c2)n(C)n1 +Cc1cc(S(=O)(=O)N2CCC(CO)CC2)ccc1F +Cc1nc(C(C)C)sc1C(=O)NCC1=NC=NC(=O)C1 +CCCCN(CC)S(=O)(=O)Cc1cccc(C#N)c1 +Cc1ccc(NC(=O)CN(C)C(=O)Cn2c(C)c(C)sc2=O)cc1 +C=CCOC(=O)c1sc2nc(-c3ccncc3)[nH]c(=O)c2c1C +CC(C)C(=O)N1CCCC1C(=O)N1CCC(C(N)=O)CC1 +Cc1cc(NC(=O)N(Cc2cccs2)CC2CCCO2)no1 +C=CCN(Cc1cccc(NC(C)=O)c1)CC(F)(F)F +Cc1nc(Nc2ncnc(NC(C)c3ccccc3)c2N)sc1C +COc1ccc(O)c(C(=O)N2CCCC(C)C2C)c1 +CCCc1nnsc1C(=O)NCC(O)c1cn(C)c2ccccc12 +NC(=O)C1(CNC(=O)NCCc2ccccc2)CCOCC1 +CC1Oc2ccccc2N(CC(=O)N(CC2CCOC2)C2CC2)C1=O +Cc1nc(C(C)(C)NS(=O)(=O)N(C)C(C)C)sc1C +C=CCN(C)C(=O)c1cc(-c2ccccc2OC)n(CC)n1 +CC(C)(C)c1noc(C(N2CCOCC2)N2CCOCC2)n1 +O=C(NCCS(=O)(=O)c1ccccc1)NCc1cccnc1 +CCCOc1ccc(Cl)cc1S(=O)(=O)N1CCOCC1 +COCC(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O +COCCNC(c1c(C)nn(-c2ccccc2)c1C)C(F)(F)F +CCCC1CN(C(=O)C2CSc3ccccc32)CCO1 +CC(C)(C(=O)N1CCNC(=O)CC1)c1ccccc1 +O=C(NCCOC(=O)c1ccc(Cl)cc1)c1cccnc1 +Cc1ccc(CN(C(=O)c2cnn3cccnc23)C2CC2)cc1 +Cc1nnc(CN(C)CCc2nc(-c3ccc(Cl)cc3)no2)n1C +Nc1ccc2c(c1)N(S(=O)(=O)c1cn[nH]c1)CC2 +Cc1ccc(CN2CC3CCN(c4cnn(C)c4)C(=O)C3C2)s1 +Cc1ccc(F)cc1Cn1ccnc1-c1ncc[nH]1 +O=C(NCc1ccccc1)NC1(C(=O)N2CCCC2)CCCCC1 +Cc1ncccc1CN(C)Cc1ccc(F)cc1Cl +CCOC1CCN(C(=O)C2Cc3ccccc3CN2C(C)=O)CC1 +CC1CCCCN1C(=O)Nc1nc2ccccc2s1 +Cc1ccc(-n2cc(C(=O)N(C)C)c(-c3ccccc3)n2)cc1 +CS(=O)(=O)NCc1nnnn1-c1ccc(Cl)cc1 +CC(C)C(=O)c1ccccc1NC(=O)CN(C)C(=O)c1ccccc1 +CC(=O)NCc1ccc(-c2csc(Cc3csc(C)n3)n2)s1 +O=C(NCc1cccc(C(=O)N2CCCC2)c1)NCC1CC=CCC1 +Cc1cc(C)c2c3ccccc3n(CCNS(=O)(=O)N(C)C)c2n1 +CCc1cccc(C)c1NC(=O)N1CCOC(CC)C1 +O=C(Nc1ccc(F)cc1)N1CCCC1c1nc(C2CC2)no1 +CCOC(=O)c1sc(C(N)c2ccccc2)nc1C +O=c1c2c3c(sc2ncn1CCOc1ccc(F)cc1)CCC3 +CCN(CC)C(=O)CCC(=O)NC1CC2CCC1(C)C2(C)C +Cc1cc(C(=O)NC2CCN(C(=O)c3ccco3)CC2)c(C)s1 +CCCC(=O)N(C)C(c1cccc(F)c1)c1ccccn1 +Cc1nc(C2CCN2S(=O)(=O)c2cn[nH]c2)cc(N(C)C)n1 +CCOc1ccccc1CCC(=O)Nc1nnc(C2CC2)s1 +Cc1ccc(OCCCn2nnc(CO)c2C2CCCO2)cc1 +CC(Sc1ccc(Cl)cc1)C(=O)N1CC(O)C1 +C=CCNC(=O)Nc1ccc(C)cc1OCC(=O)N(C)C +Cc1n[nH]c2ncc(C(=O)NC(C)c3ccc(-n4cncn4)cc3)cc12 +Nn1cnnc1SCC(=O)Nc1nccs1 +OC(c1ccsc1)(C(F)(F)F)C(F)(F)F +Cc1nnc2c(N3CCN(c4ccccc4)CC3)nc3ccccc3n12 +COc1cccc(NC2CCN(C(=O)c3ccoc3)CC2)c1 +CCn1cc(S(=O)(=O)NCCc2ccc(OC)cc2)cn1 +Cn1c(C(F)(F)F)nn(CC(=O)NCCc2ccccc2)c1=O +CCCN(CC1CC1)S(=O)(=O)N1CCCC(O)C1 +CC(C)C(C)NC(=O)COc1ccc(F)c(F)c1 +O=C(COc1ccc(F)cc1)Nc1nnc(C2CCCCC2)o1 +Cc1ccc(NC(=O)NC2CCN(S(C)(=O)=O)CC2)cc1F +Cc1ccc(NC(=O)CNc2ccc(C(=O)N(C)C)cc2)c(C)c1 +Cc1nc(C2CC2)nc2sc(C(=O)OCCO)c(C)c12 +CC(C)C(NC(=O)NCC(=O)N(C)C)c1ccccc1 +Nc1cc(F)cc2c(Nc3ccccc3)nccc12 +CCOc1ccccc1NC(=O)CSc1nnc(C2CC2)n1C +Cc1n[nH]c(C2CN(C(=O)c3ccc4c(c3)nc(C)n4C)CCO2)n1 +Cc1cc(=O)oc2cc(NC(=O)NC(C)CN3CCCC3=O)ccc12 +Cc1cnc(C(=O)N2CCN(C(=O)N(C)C)CC2)cn1 +CNC(=O)C1Cc2ccccc2CN1CCc1cccs1 +CCCC1CN(C(=O)C2(C)CC2(Cl)Cl)CCO1 +CC(O)CN(Cc1nc(C2CC2)n[nH]1)c1ccccc1 +O=C(COc1cccc(Cl)c1)Nc1cccc(N2CCCC2=O)c1 +COCCN1CC(C(=O)Nc2cc(-c3ncco3)ccc2C)CC1=O +CCn1nc(C)cc1NC(=O)c1cccc(OCc2nnnn2C)c1 +Cc1cccc(C(C)C)c1NC(=O)CCCNC(=O)c1cccs1 +CCOc1cc(F)ccc1NC(=O)Cn1nc2ccccn2c1=O +CC1CN(C(=O)Cn2nc(-c3ccccc3)ccc2=O)c2ccccc21 +CC(COc1ccc(F)cc1F)NC(=O)c1cccc(NC(N)=O)c1 +CN1C(=O)CCc2cc(NC(=O)c3ccc(F)cc3F)ccc21 +Cc1nn(CC(=O)NC2CCCCC2)c(=O)c2noc(C)c12 +COCCOc1ncccc1NC(=O)N1CC(C)CCC1C +CCOC(=O)c1cc(C(C)C)sc1NC(=O)c1c(C)noc1C +Cc1nnc(SCC(=O)c2ccc3c(c2)OCCO3)n(N)c1=O +Cc1ccsc1C(=O)Oc1cccc(C(=O)N(C)C)c1 +O=C(NC1CC1)c1cc2sccc2n1CCOc1ccccc1 +Cc1cc(CNc2nnc(C(F)(F)F)s2)ccc1-n1cncn1 +N#Cc1ccc(OCCOc2ccc(-n3cnnn3)cc2)cc1 +O=C(NCCc1nnc2n1CCC2)c1ccc(Cl)c(Cl)c1 +Cc1noc2ncc(C(=O)N3CCN(S(C)(=O)=O)CC3)cc12 +CCOc1ccc(Cl)c2c1CCNC2c1cc[nH]c1 +Cc1ncc(-c2ccncc2)c(C2CCCN(Cc3cccnc3)C2)n1 +CCOC(=O)C1CCCN1C(=O)c1cc(C)sc1C +Cc1cccc(OCCCn2nncc2-c2ccc(N)cc2)c1 +C#CCN1CCC(C(=O)Nc2cccc(N3CCOC3=O)c2)CC1 +Cc1ccc(NC(=O)C2CC(=O)N(c3cccc(Cl)c3)C2)nc1 +CC(C)NC(=O)Cn1cnc2nc(N3CCOCC3)sc2c1=O +NC(=O)CN(C(=O)c1ccc(N2CCOCC2)cc1)C1CCCC1 +CCCOC(=O)c1cccc(NC(=O)c2cccnc2)c1 +Cc1ccc(NC(=O)COC(=O)c2nccc3ccccc23)cc1 +Cc1cc(C)n(C2CCCN(C(=O)C3COc4ccccc4O3)C2)n1 +COc1ccc(S(=O)(=O)N(C)C)cc1C(=O)NC(C)(C)C +CSc1nc2ncn(CC3CCCCO3)c(=O)c2s1 +Cc1c(C(=O)Nc2ccccc2O)cnn1-c1ccncc1 +Oc1cc(Cl)c2c(c1)C(C1CCOCC1)NCC2 +CCOC(=O)c1ccc(CN2CCOC(c3cccs3)C2)o1 +COc1cc(C)nc(N2CCN(C(=O)c3cnc(C)s3)CC2)n1 +O=C1CN(c2ccc(-c3ccccc3)nn2)CCCN1 +O=C(NCc1ccncc1)C1(c2ccc(F)cc2F)CCCC1 +COc1ccc(NC(=O)Nc2c(C)cccc2C)cc1 +Cc1ccsc1CN(C)C(=O)C1CC(=O)N(Cc2ccccn2)C1 +CC(O)CCNC(=O)Nc1ccnc(C(=O)N(C)C)c1 +Cc1nnc2n(c1=O)N=C(c1ccc(Cl)cc1)CS2 +Cc1ccc(C(=O)CCC(=O)N(C)c2ccccn2)s1 +CCN(CCC#N)C(=O)CNc1ccccc1C(=O)N1CCCCC1 +Cc1cc(Cl)ccc1OCC(O)c1ccccc1N +C#CCC(OC(=O)Cc1coc2cc(OC)ccc12)c1ccccn1 +Cc1ccc(NC(=O)c2cn(C)c3cccc(N)c3c2=O)cc1C +Cc1ccc(NC(=O)c2ccccc2SCC(N)=O)cc1C +Cc1c(NS(C)(=O)=O)cccc1C(=O)NC1CC1 +CCN1CC(C(=O)NCc2cc(C)nn2C)CC1=O +COc1cc(C#N)ccc1OC(=O)c1cc2cccc(OC)c2o1 +CC1CC(=O)NCCN1c1ccc2nnc(C(F)(F)F)n2n1 +CCn1c(-c2ccc(C)cc2)ccc(CC#N)c1=O +CCC(C)(C)NC(=O)NC(c1ccccn1)c1ccccc1OC +CCc1nc(COC(=O)C2CCN(C(=O)C(C)(C)C)CC2)cs1 +COCCNC(=O)Nc1ccc(-c2ccccc2)cc1 +N#CCC(=O)Nc1nc(-c2ccc3c(c2)OCCO3)cs1 +CC(C)Oc1ccc(CNC(=O)NCCc2ccccn2)cc1 +CCOc1ccc2ccccc2c1C(=O)NCc1cc(C)on1 +CC1(C)CN(Cc2c(Cl)ccc(O)c2Cl)CCO1 +CCOC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O +O=C(c1cc(Br)c[nH]1)N(CC(F)(F)F)C1CC1 +O=C(Cc1ccc(F)cc1F)N(Cc1ccco1)CC1CCCO1 +O=C(Cn1nc(-c2ccncc2)oc1=O)N1CCCCC1 +Cc1ccc(NC(=O)c2cc(Cl)ccc2Cl)cn1 +COC(=O)C(NC(=O)OCc1ccccc1)c1ccco1 +CC(Cc1ccco1)NC(=O)c1cccnc1SC(C)C +Cn1nnnc1SCCC(=O)NCC(C)(O)c1ccc(F)cc1 +Cc1c(C#N)c(=O)ncn1N(C)c1ncc(C(F)(F)F)cc1Cl +CCOc1ccc(C(C)NC(=O)C(C)NC(C)=O)cc1 +COCCN(C)C(=O)CCSc1ccc(Br)cc1 +Cc1nn(C)c(C)c1CCNC(=O)NC(C)c1ccc(F)c(F)c1 +COC(=O)C1c2ccsc2CCN1C(=O)Cn1cccn1 +CNc1ncccc1C(=O)Nc1cccc(C(=O)NC(C)(C)C)c1C +CCNC(=O)c1cc(=O)c2cc(N)cc(Cl)c2o1 +O=S(=O)(NCC(O)c1ccc(F)cc1)c1ccccc1 +CN(c1ccc(C(=O)Nc2cccnc2)cc1)S(C)(=O)=O +Cc1cc(C)n(-c2ccccc2NCc2cnn(C)c2C)n1 +O=C(c1cccnc1-c1cccc(-c2cc[nH]n2)c1)N1CCCC1 +COCCNC(=O)Cn1nnc(C(=O)OC)c1N +O=C(c1ccc(S(=O)(=O)Cc2ccccc2F)cc1)C1CC1 +Cc1ccc(-c2nc3sc(C4CCCO4)nn3c2CO)cc1 +CCCCS(=O)(=O)NCc1cc(Cl)c2c(c1)OCCO2 +CC(OC(=O)c1cnccn1)C(=O)N1CCc2sccc2C1 +COc1ccc(OC)c(C(=O)Nc2nccs2)c1 +CC1CCc2c(sc(NC(=O)C3CC3)c2C(N)=O)C1 +Cc1nn(C)c(C)c1C(=O)N1CCN(C(=O)N(C)C)CC1 +COC(=O)c1cc(CCN2CCOCC2)nn1CCO +CSc1ncc(C(=O)NCCNC(C)=O)n1-c1ccc(F)cc1 +N#CCCCCN1CCOC(c2ccccc2Cl)C1 +O=C(c1cc(Br)c[nH]1)N(Cc1ccsc1)C1CC1 +N#Cc1cccc(S(=O)(=O)Nc2ccccc2N2CCCC2=O)c1 +Cc1ccc2c(cnn2CCC(=O)Nc2ccc3c(c2)OCCO3)c1 +Cc1cc(C(=O)NCc2ccccc2)c2cnn(C(C)C)c2n1 +O=C(NCc1ccnc(-n2ccnc2)c1)C1(Cc2ccccc2)CCC1 +COc1ccc(C(C)N2Cc3ccc(N)cc3C2=O)cc1 +CC1CCCN(S(=O)(=O)c2cnn(C(C)C)c2)C1 +CCCS(=O)(=O)N1CC2CC(C(=O)N3CCOCC3)C(C1)O2 +CCCc1cc(=O)[nH]c2nnc(SCC(=O)OCC)n12 +Cc1nc(CNC(=O)NC2CCCc3c2cnn3CCO)cs1 +CCn1ncc(C(=O)N2CCN(c3ccccc3C)C(=O)C2)c1C +COc1ccc(-c2csc3ncn(CCC#N)c(=O)c23)cc1C +CN(CC(O)CO)C(=O)Nc1ccc2[nH]ccc2c1 +CCOc1ccc(CC(=O)NCc2nnc(SC)n2C)cc1 +CC(NCc1nc2ccccc2c(=O)[nH]1)c1ccccc1 +CCN(CC)C(=O)c1cc(OCC(=O)N(C)C)n(C)n1 +CCc1cc(NC(=O)c2cn(C)c(=O)[nH]c2=O)c2ccccc2n1 +Cc1ccc(-c2nccn2CCc2c[nH]cn2)c(C)c1F +COc1ccc(C(=O)N=c2[nH]nc3cc(C)ccn23)cc1OC +CC(=O)Nc1ccc(C(=O)NCCNC(=O)C(C)C)cc1 +Cc1nnc(-c2cccn2CC(=O)Nc2ccc(F)c(Cl)c2)o1 +CC(C)Cn1c2c(ccc1=O)CC(NC(=O)c1cscn1)CC2 +Cc1cc(-c2nnc(NC(=O)c3ccc4ncsc4c3)o2)n(C)n1 +O=C(NCCCO)c1cnc2c(cnn2Cc2ccccc2)c1 +c1cc(C2CCCC2)nc(NCCc2nccs2)n1 +N#Cc1cccc(C(=O)Nc2cccnc2-n2cccn2)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1csc2c1CCC(C)C2 +O=S(=O)(c1c(Cl)cc(Cl)cc1Cl)N1CCNCC1 +COc1cc(C(=O)N2CC(C)OC(C)C2)cc(OC)c1C +Cc1csc2cc(C(=O)NCc3c(F)cccc3F)cnc12 +O=C(Nc1cc(F)c2[nH]c(=O)ccc2c1)c1cccc(F)c1 +O=C(NCCCc1ccccc1)c1ccc(N2CCCC2=O)cc1 +Brc1ccc(OCCOC2CCC2)cc1 +Cc1cccc(C(=O)N2CCc3ccc(O)cc3C2)n1 +CCOC(=O)c1ccc(S(=O)(=O)N2CC(C)CC(C)C2)cc1 +Cc1nccn1-c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cn1 +O=C(NCc1ccccc1F)c1ccccc1CSc1ncn[nH]1 +CCOC1CCN(C(=O)c2ccc(C(N)=O)nc2)CC1 +COc1ccccc1N1CCN(c2ncnc3[nH]cnc23)CC1 +CCC(CC)C(=O)OCc1cc(=O)n2nc(C(C)C)sc2n1 +COCCCC1CCCN(C(=O)c2ccn(C(C)(C)C)c2)C1 +Cc1nc(-c2cccc(NC(=O)NCCCOC(C)C)c2)oc1C +Cc1ccc(OCCN2C(=O)c3ccccc3S2(=O)=O)cc1 +CC(C1CC1)N(C1CC1)S(=O)(=O)c1cccc(S(C)(=O)=O)c1 +CCOCC(=O)NCC1CC(=O)N(c2ccc3c(c2)OCO3)C1 +Cc1cccc(S(=O)(=O)NCC(C)(C)c2ccncc2)c1C#N +COc1cc(NC(=O)CCSc2ccccn2)cc(OC)c1 +Cc1c(C(N)=O)nnn1CC(=O)N1CCCCCC1 +Cc1ccc(OCCCCC(C#N)C(=O)N2CCCC2)cc1 +CC(C)C(=O)Nc1ccc(NC(=O)Cc2ccccc2)cc1 +Cc1cnc(Oc2ccc(Br)cc2)c(N)c1 +Cc1ccc(N2CC(C(=O)N3CCOCC3)CCC2=O)cc1C +Cc1ccc(S(C)(=O)=O)cc1C(=O)NC(C)C1CCCO1 +Cc1cc(N)nc(SC(C)C(=O)Nc2ccc3c(c2)OCCO3)n1 +O=C(Nc1nccs1)C(C(F)(F)F)C(F)(F)F +CC(=O)Nc1ccc(CC(=O)Nc2ccccc2C(C)=O)cc1 +CC(=O)NCC(=O)Nc1cc(-c2ncco2)ccc1C +CCOC(=O)C(O)Cc1cc(C(=O)OC)ccc1F +CC1Cc2cc(N)ccc2N1C(=O)c1ccsc1 +Nc1nc(-c2ccccc2)nn1C(=O)c1ccccc1F +O=C(CNC(=O)c1n[nH]c2cc(Cl)ccc12)NC1CCCC1 +COc1ccccc1NC(=O)COC(=O)c1cnc(C)cn1 +CC(C)CC(=O)N(Cc1cccnc1)c1ccc(Cl)cc1 +COC(=O)C(CNC(=O)C1(C#N)CCCCC1)Oc1ccc(F)cc1 +COCC(=O)NCc1ccc2c(c1)N(C(=O)c1ccccc1C)CC2 +COc1ccc(OCc2nn3c(C(F)(F)F)nnc3s2)cc1 +O=C(NC1CCCCC1)c1cc(=O)[nH]c2ccc(Br)cc12 +CCn1nc(C)cc1C(=O)NCC(=O)Nc1c(C)nn(C(C)C)c1C +COc1ccc(NC(=O)CNS(C)(=O)=O)cc1C +Cc1ccccc1C1CC(=O)c2cnc3ccnn3c2C1 +CNC(=O)c1cc(C)ccc1NC(=O)Cc1ccccc1OC(C)C +COc1ccccc1N1CCC(Nc2ccc3n[nH]c(=O)n3n2)C1 +CC(=O)c1ccccc1NCC(=O)Nc1ccc(F)cc1 +CC(C)(O)CNC(=O)c1cc(-c2cccs2)n(-c2ccccc2)n1 +O=C(COc1ccccc1CO)Nc1ccc(F)cc1Cl +O=C1CCCCCN1CCNS(=O)(=O)N1CCCCC1 +CCOC(=O)Cn1nnc(-c2ccc(SC)cc2)n1 +c1cc(CNc2cnccn2)cc(CN2CCOCC2)c1 +O=C(c1ccc(F)cc1)N1CCN(Cc2ccc(F)cc2F)CC1 +Cc1ncc(CNS(=O)(=O)N(C)CCC#N)s1 +Cc1cc(C)c(CNc2ccccc2C(=O)N2CCOCC2)c(C)c1 +CC(C)c1n[nH]c(NC(=O)Cn2nc(-c3cccs3)ccc2=O)n1 +COC(=O)N1CCC(NC(=O)Cc2c(F)cccc2F)CC1 +COCCn1cnnc1CN(C)c1cc(C)nc2cc(C)nn12 +COc1cc(NCC2Cn3nnc(-c4ccccc4)c3CO2)ncn1 +O=C(Nc1ccc(F)cc1F)c1ccnc(-n2cncn2)c1 +Cc1cccc(NC(=O)c2coc(NC(=O)c3ccco3)n2)c1 +COCCS(=O)(=O)Nc1c(C)c(C2CC2)nn1-c1ccccc1 +Cc1ccc2c(c1F)C(CC1CCOCC1)NCC2 +COc1ccc(C(=O)N(Cc2cccnc2)Cc2ccco2)cc1F +Cc1ncc(CNC(=O)c2cc(F)ccc2C)s1 +CCNS(=O)(=O)c1cccc(C(=O)Nc2ccccc2)c1 +Cc1cc(C(=O)Nc2ccccc2C(=O)NCC(C)C)[nH]n1 +NC(=O)C1CCCN(C(=O)Cc2c[nH]c3ccccc23)C1 +CCOC(=O)CCCn1cnc2ccc(Br)cc2c1=O +COC(=O)c1cc(C)ccc1NCc1nsc(N(C)C)n1 +CCc1noc(CC)c1CNC(=O)Cc1cc(-c2ccccc2)on1 +CC(C)c1ccc(C(C#N)N(C)C(=O)C2CCCO2)cc1 +COc1c(O)ccc2c1C(c1ccc(O)cc1)NCC2 +Cc1cc(C)n(C2CN(Cc3ccc(C(N)=O)cc3)C2)n1 +Cc1oc2ncn(CC(C)C)c(=O)c2c1C(=O)NCc1ccccn1 +Cc1cc(C)n(CCCNc2ncnc3ccc(F)cc23)n1 +CN(Cc1cc(-c2ccccc2)no1)C(=O)C1CCc2ccccc21 +CCc1onc(C)c1NC(=O)N1CCCC(c2nc(C)cs2)C1 +CC(C)(C)n1cc(CN(CCC#N)Cc2ccccn2)cn1 +COc1ccc(CCNC(=O)c2ccc(N)cc2)cc1 +CC(C)(C)c1ccc(NCc2nnc(C3CC3)o2)cc1 +Cc1ccccc1C(=O)Nc1ccc(NC(=O)c2cccnc2)cc1 +Cc1ccc2oc(C(=O)N3CCC(Nc4ncccn4)CC3)cc2c1 +CC(C)n1ncc2cc(NC(=O)NCCc3ccc(F)cc3)cnc21 +O=C(CC1CCCC1)Nc1cccc(-c2ccn[nH]2)c1 +CC1CCc2ccccc2N1CCC(=O)N1CCCS1(=O)=O +CN(CCCNC(=O)OC(C)(C)C)C(=O)Nc1ccn(C)n1 +COC(=O)C(CC(C)C)NC(=O)Nc1cccc(F)c1 +COC(=O)C(C)OC(=O)c1ccc(NC(=O)c2ccco2)cc1 +Cn1nccc1CCNC(=O)Nc1ccccc1N1CCOCC1 +CC(NC(=O)NC1CCCNC1=O)c1ccc(Cl)c(Cl)c1 +O=C(NCCc1nccs1)Nc1ccccc1N1CCCCCC1 +CC1CC=CCC1COC(=O)CCn1nc2ccccn2c1=O +Cc1nc(C)n(CC2CN(C(C)C(=O)NC3CCCCC3)CCO2)n1 +CC1CCCCC1NC(=O)NCC(C)(C)NS(C)(=O)=O +Cc1cc(C(=O)NCC2(O)CCOc3ccccc32)c(C)o1 +c1cc(CN2CCOC3C(OCC4CCCC4)CCC32)co1 +CC(O)CN1CCN(CCOc2ccccc2C#N)CC1C +COc1ccc(C(=O)N2CCN(Cc3ccc(C#N)cc3)CC2)cc1 +CCCc1cc(=O)[nH]c2c1c(C)nn2-c1ccc(F)cc1 +CC(C)Oc1ncccc1CNC(=O)NC(C)C1CCCO1 +CCN(C(=O)COC(=O)c1cccc(N)c1)C1CC1 +CC(C)C(=O)N1CC(n2nc(-c3ccccc3)ccc2=O)C1 +O=C(NCc1cccnc1)c1csc(NC2CC2)n1 +CC(=O)c1ccc(NC(=O)N2CCC(CO)CC2)cc1C +O=C(CC1(Cn2cnnn2)CCCCC1)Nc1ccccc1 +COC(=O)CN(C(=O)c1cccc(Oc2ccccc2)c1)C(C)C +CC(NC(=O)Nc1cc(F)cc(F)c1)c1ccc2c(c1)CC(=O)N2 +CCOC(=O)C(N)c1c(C)nn(Cc2ccccc2)c1C +CN(Cc1ccccc1F)C(=O)CSc1nc(N)cc(N)n1 +CCn1nc(C)cc1NC(=O)Cc1c[nH]c2ccccc12 +Cc1ccc2nc(CNC(=O)C(C(C)C)N3CCCC3=O)cn2c1 +CCCCNC(=O)C1CSc2ncc(C)c(=O)n2C1 +CN1CCC(C(=O)NCc2ccc(C#N)cc2)CC1=O +CNC(=O)CN(C)C(=O)CCOc1ccc(Cl)cc1 +CC(C)NC(=O)C(NC(=O)c1cccc2ccnn12)c1ccccc1 +O=S(=O)(Nc1cccc(-c2cnco2)c1)c1cn[nH]c1 +CCC1C(=O)Nc2c(F)cc(C(O)CC(C)C)cc21 +Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)Nc1cnn(C)c1 +Nc1cc(C(=O)NCCC2CCCCC2)ccc1F +O=C(NCCc1ccc(-n2cccn2)cc1)NCc1ccco1 +O=C(CCOc1ccc(F)c(F)c1)n1ccnc1 +N#Cc1c(F)cccc1Sc1nnc2n1CCCCC2 +CCOc1ccccc1NC(=O)c1nccc2c(N)cc(C)cc12 +Cc1ccc(CNS(N)(=O)=O)c(Oc2ccccc2)c1 +CC(NC(=O)C1CCN(C(N)=O)CC1)c1ccccn1 +O=C(Nc1cccs1)N1CCN(c2ncccn2)CC1 +COc1ccccc1NC(=O)COC(=O)c1cc(F)cc(F)c1 +CCCn1nnnc1COC(=O)c1nn(C)c(=O)c2ccccc12 +O=C(Nc1cc(C(F)(F)F)ccc1Cl)c1ccoc1 +Cc1ccc(S(=O)(=O)NC2(C#N)CC2)cc1Br +COCCCNC(=O)Cn1c(=O)c(C(F)(F)F)nc2ccccc21 +Nc1[nH]nc(O)c1Cc1ccccc1Br +CC(=O)N1c2ccccc2CC1C(=O)NCC(C)(C)c1cccs1 +O=C(c1ccoc1)N1CCC2(CC1)CN(Cc1nccs1)CCO2 +C=CCN(CC=C)C(=O)c1ccc(NC(=O)C2CC(=O)N(C)C2)cc1 +COc1cccc(C(=O)NCc2cc(C#N)ccc2F)c1F +CCN(CC)C(=O)c1cccc2c1-c1ccccc1C2=O +CCC1(C)Cc2ccccc2-c2[nH]c(=O)[nH]c(=O)c21 +Cc1ccc(Cl)cc1NCc1cc(C(N)=O)ccc1F +O=C(Nc1ccc(C(=O)N2CCCCCC2)cc1)C1CCC1 +CCOc1ncccc1CN(C)C(=O)NCc1ccc(OC)cc1 +Cc1nnc(N2CCCC(c3noc(C(C)C)n3)C2)c(C#N)c1C +CC(C)C(Sc1n[nH]c(=O)n1C1CC1)C(=O)Nc1ccccc1 +CS(=O)(=O)c1ccc(NCC2CCCCC2)c(N)c1 +CCOCC1CN(S(=O)(=O)Cc2ccccc2)Cc2nccn2C1 +Cc1n[nH]c2ncc(C(=O)N3CCN(Cc4ccccc4)CC3)cc12 +COc1ccc(CNC(=O)C(C)Oc2ccccc2Cl)cc1OC +CCCCN(C)C(=O)Nc1cc(C(=O)NC2CC2)ccc1C +c1ccc(N2CCN(Cc3cnc(N4CCOCC4)s3)CC2)cc1 +COc1cc(N)ccc1S(=O)(=O)Nc1ccn(C)n1 +CC(NC(=O)CCc1ccccc1)C(=O)N1CCCCC1 +O=S(=O)(c1cccnc1)N1CCCCC1CCn1cccn1 +CCCOC(=O)c1ccc(NC(=O)NCc2cnc(C)s2)cc1 +CCNc1ncccc1S(=O)(=O)N(C)C(C)CC#N +CCN(CC(=O)Nc1cc(Cl)ccc1C)C(=O)c1oc(C)nc1C +CCCn1ccc2ccc(NC(=O)NC3CCN(C)C3=O)cc21 +Cc1nnsc1C(=O)Nc1sc2c(c1C#N)CCCC2 +CC(CO)NC(=O)CCc1ccc(-c2ccccc2F)o1 +Cc1cc(NC(=O)c2nc3nccc(C)n3n2)ccc1C(=O)N(C)C +Nc1nnc2scc(-c3ccc4c(c3)OCCCO4)n12 +Cc1ccc(F)cc1S(=O)(=O)N1CCCC(C2OCCO2)C1 +CCOCCCNC(=O)N1CCN(C(=O)N(C)C)CC1 +CC(C)c1nnc(C2CCN(C(=O)c3cccn(C)c3=O)CC2)o1 +CCOc1ccccc1-c1nc2cc(N)ccc2o1 +CCc1cc(OC2CC2)ccc1NS(C)(=O)=O +O=C(CSc1ncccn1)Nc1ccc(C(=O)NC2CC2)cc1 +COc1ccc(Cl)cc1Cn1c(=O)c(C#N)cn(C)c1=O +O=C(NCc1ccccc1F)c1cn2cccnc2n1 +COc1ccc(CNC(=O)CNC(=O)c2ccc(F)cc2)cc1 +Cc1ccc(NC(=O)c2cnc3[nH]nc(C)c3c2)cc1F +CCNc1ccc(C(=O)N(CCO)CCO)cc1C +CCn1ccc2oc(C)c(C(=O)NC3CCCCC3)c2c1=O +Cc1noc(CCCC(=O)N(CC2CCOC2)C2CC2)n1 +CC(=O)N1c2ccc(S(=O)(=O)Nc3cn[nH]c3)cc2CC1C +O=S(=O)(c1ccn(S(=O)(=O)c2ccccc2)c1)N1CCCC1 +CC(NC(=O)c1cnc2ccccc2n1)c1ccccc1 +CC(C)CC(=O)Nc1cnn(C2CCOCC2)c1 +CCC(CO)Nc1nc(C(F)(F)F)nc2ccccc12 +CC(C)CC(=O)Oc1ccc(NC(=O)c2ccco2)cc1 +Nc1ccc(O)c(-c2n[nH]c(-c3cccnc3)n2)c1 +Cc1noc(Cc2ccccc2NC(=O)c2ccc[nH]c2=O)n1 +CCNC(=O)CNC(=O)c1sc(C)cc1OC +Cc1nnc2n1CC(NC(=O)c1cccc(Cn3ccnc3)c1)CC2 +CCCCNC(=O)c1sc2nc3n(c(=O)c2c1C)CCCCC3 +CCCc1nnc2c3cnn(-c4cccc(Cl)c4)c3ncn12 +Cc1ccc(CN(C)C(=O)Nc2ccccc2F)s1 +CCSc1nnnn1-c1cccc(NC(C)=O)c1 +CCN(C(=O)Nc1cccc(F)c1)C1CCN(c2ccccc2)C1=O +COc1ccc2nc(C)cc(NC(=O)c3ccc4nccnc4c3)c2c1 +Cc1ccc(NC(=O)C2CC(=O)c3ccccc32)nc1 +COc1ccccc1CNc1ncc(N)cc1OC +COc1cccc(CNC(=O)c2nc(-c3ccccc3)oc2C)c1 +CCC1CCCN(C(=O)C2CCN(C(=O)N(CC)CC)CC2)C1 +Cn1cnc2cc(OC(=O)c3cccc(F)c3)ccc21 +CN(Cc1ccccc1N1CCCC1)C(=O)C1CCC(=O)N1 +O=C(c1ccc(F)cc1)N1CCN(Cc2ccsc2)CC1 +O=C(Nc1nc[nH]n1)c1sccc1S(=O)(=O)N1CCCCC1 +O=C(CC1C(=O)Nc2ccccc21)Nc1ccc(SC(F)F)cc1 +CCC(O)CN1CCN(C(=O)c2ccc3c(c2)OCO3)CC1 +COc1ccc(-c2cn[nH]c(=O)c2CC#N)cc1Cl +COC(=O)C(C)(C)NC(=O)Cc1ccc(C)s1 +Cc1noc(CCCC(=O)NCC(C)(C)c2ccncc2)n1 +CCn1nc(C(=O)Nc2sc3c(c2C#N)CCC3)cc1C +Cc1cc(CSc2nnc(NC(C)C)s2)on1 +COc1ccc2cc3c(nc2c1)N(C(=O)C(C)C)CC3 +Cc1cc(C)n(CCOC(=O)c2ccc3c(C)nn(C)c3n2)n1 +CC(C)CCc1noc(Cn2cnc(C3CCC3)cc2=O)n1 +COCCn1ccc(NCc2cccc(-c3ccncc3)c2)n1 +CCc1ccccc1OC(=O)Cn1c(=O)cnc2ccccc21 +CCOCCOc1c(Cl)cccc1NC(=O)C1CC1 +C#CCOC(=O)C(CC(C)C)N1CCCCC1=O +CC(c1cccs1)N(C)CCCN1CCOCC1 +Nc1c(C(=O)Nc2ccccc2Cl)nnn1-c1ccc(Cl)cc1 +CCCCn1nc(C(=O)Nc2nc(C)cs2)ccc1=O +CCc1noc(CC)c1CNC(=O)NCc1cccc(OC)c1 +N#CCc1ccc(NC(=O)COc2cccc(N3CCCC3=O)c2)cc1 +Nc1cccnc1NCCCNC(=O)c1ccccc1 +CCn1cc(C(=O)NC2CCN(c3cc(Cl)ccc3OC)C2)cn1 +CC(=O)NCCCC(=O)NCC(=O)Nc1nccs1 +CCC(C(=O)NCCc1ncc(C)s1)c1ccccc1 +O=C(Nc1nncs1)N1CCC(Cc2cccc(F)c2)CC1 +COc1ccc(NC(=O)Cc2ccccc2Cl)cc1OC +O=C(NCC1(N2CCOCC2)CCCCC1)c1ccccc1 +O=C(NCCC(c1ccccc1)c1ccccc1)c1ncccn1 +O=C1Cc2cc(NC(=O)NCc3ccccc3)ccc2N1 +COc1cccc2cc(CNc3c(C)c(C)nc4ncnn34)oc12 +CN(C)c1nc(C(=O)NCCc2ccccc2)nc2c1cnn2C +COC(=O)c1ccc(F)c(NC(=O)c2cc(C)oc2C)c1 +COCCC(=O)N1CCC(N2CCOCC2)C1Cc1ccccc1 +CC(C)C(=O)N1CCCC2(CCCN2C(=O)CCc2ccccc2)C1 +Cc1ccc(F)cc1C(=O)NCCc1ccc(S(N)(=O)=O)cc1 +CCCC1CN(C(=O)Cc2c(C)[nH]c3ccnn3c2=O)CCO1 +CC1(C(=O)Nc2ccc3c(c2)OCCO3)CC1(Cl)Cl +Cc1cc(C(=O)NCC(=O)NCc2ccncc2)c(C)o1 +CC(NC(=O)c1cccnc1)c1ccc(Cl)cc1Cl +Cc1ccnc2nc(C(=O)N3CC(C)Sc4ccccc43)nn12 +CCOc1ccc2c(C(=O)Nc3cnn(CC)c3C)cc(=O)oc2c1 +CCOc1ccc(NS(=O)(=O)c2cn[nH]c2C)cc1CO +CCc1onc(C)c1NC(=O)c1ccc(N2CCCC2)nc1 +CC(C)c1nc2ccccc2c(=O)n1NC(=O)c1ccccc1 +COCCn1nnnc1C(C(C)C)N1CCc2ccccc21 +CC(C(=O)N1CCN(CC(O)C(C)(C)C)CC1)n1ccnc1 +O=C(CC(c1ccco1)n1cccc1)Nc1ccccn1 +CCCN(CC(F)F)C(=O)c1ccc(-n2ccnn2)cc1 +CCN(Cc1ccccc1)C1COc2ccc(C)cc2C1O +CCOc1cc(C)ccc1NC(=O)c1ccc(C)nc1 +Cc1ccccc1NCc1nnc(-c2ccccc2)o1 +O=C(Nc1nc(CC(=O)N2CCCCC2)cs1)c1ccc(F)cc1 +Cc1ccc(S(=O)(=O)CCc2nc3ccccc3s2)cc1 +COC(=O)c1cccnc1N1CCC(c2cc(OC)ccc2OC)C1 +O=C(COc1ccc(F)cc1F)Nc1cc(N2CCCCC2)ncn1 +COc1ccccc1COCC(O)Cn1ncc2ccccc2c1=O +CCC(=O)Nc1ccc(C(=O)NCCN2CCOCC2)cc1 +Cc1csc(C2CCCN(C(=O)CCC3CCCO3)C2)n1 +O=C(NCCNC(=O)c1ccc(NC2CC2)nc1)NC1CCCCC1 +COC(Cc1ccc(S(C)(=O)=O)cc1)(OC)OC +NC(=O)COc1ccc(CNc2ccccc2)cc1Br +COc1cccc(NC(=O)Nc2ncccc2C)c1 +COc1cccc(Cl)c1CC(=O)NC(C)c1noc(C)n1 +O=c1c2ccccc2nnn1CSc1ccc(C(F)(F)F)cn1 +Cc1ccc(C(=O)N(C)CC(=O)NC2CC2)cc1N +COc1cc(NC(C)=O)c(Cl)cc1C(=O)NCc1ccco1 +O=C(COc1ccc2ccc(=O)oc2c1)Nc1cc(Cl)ccc1O +CC(=O)N1CCCC1C(=O)Nc1nn(-c2ccccc2)cc1C +CC(=O)Oc1ccc(C=c2sc3ncnn3c2=O)c(OC(C)=O)c1 +Cc1ccccc1OCCc1nc(C)c(CC#N)s1 +CC(C)CC(=O)Nc1ccccc1N1CCNC(=O)C1 +Cc1cc(F)ccc1NS(=O)(=O)c1ccc2c(c1)CC(=O)N2 +CC(O)CNC(=O)c1cccc(Br)c1 +CCn1nnnc1-c1cccc(C(=O)NCCCN2CCOCC2)c1 +Cc1ccc(NC(=O)Cc2nc(-c3ccccc3)n[nH]2)cc1F +CCC(CC)c1nnc(NC(=O)Cc2ccc(F)c(F)c2)s1 +Cc1cnn(CCC(=O)NCCC(=O)N2CCCCC2C)c1 +CC(NC(=O)NCc1ccsc1)c1ccc(Br)cc1 +COc1ccc(F)cc1C(=O)OCc1cccc(C(N)=O)c1 +Nc1ccc(F)cc1C(=O)NC1CCC(O)CC1 +COc1cc(C(C)NC(=O)NC(C)C)ccc1OC(C)C +COc1cccc(CN(Cc2cccn2C)CC2CCCO2)c1 +CCCNc1snnc1COC1CCC(C)CC1 +COCc1cccc(C(=O)OCc2ccoc2C)c1 +O=C(NCCC1=CCCCC1)C1CCCN(c2ncccn2)C1 +COc1cccc(C(=O)Nc2cccc(OCC3CCCO3)c2)c1F +CCC(C)NC(=O)Nc1ccc(CC(=O)NC(C)C)cc1 +CC(Cc1cccs1)NC(=O)N1CCN(S(C)(=O)=O)CC1 +Cc1ccc(C(=O)NCc2cccc(CN3CCCC3=O)c2)cc1 +Cc1nc(CNC(=O)c2ccc(F)c(-n3cccn3)c2)no1 +Cc1nonc1C(=O)NCCCCC(F)(F)F +COc1cccc(COc2cccc(C(C)O)c2)c1 +CC1CCCN(c2nn3c(C(=O)N4CCCC4)cc(=O)nc3s2)C1 +CN(C)C(=O)CN1CCc2onc(-c3ccccc3F)c2C1 +CCn1nc(C(=O)Nc2ccc(Cl)c(Cl)c2)ccc1=O +CCSc1nnc(NC(=O)c2ccc3c(OC)n(C)nc3c2)s1 +CCCCOC(=O)c1cccc(Nc2nc(=O)c(C)n[nH]2)c1 +Cc1ncc(C(=O)NCC(O)C(C)C)c(Cl)c1Cl +O=C(CN1CCOCC1)N1CCSc2ccccc21 +O=C1CC(C(=O)N2CCCCC2Cn2cccn2)CN1C1CCCC1 +CCc1c(C(=O)NCC(C)(C)c2ccncc2)[nH]c(C)c1C(C)=O +CCOC(=O)N1CCC(NC(=O)c2ccc(OC(F)F)cc2)CC1 +Cc1ccc(OCC(=O)N(C)Cc2ccc3c(c2)OCCO3)cc1C +CC(C#N)CN(C)C(=O)c1cn(-c2ccccc2)nn1 +CC(C)C(=O)NCCNC(=O)NCc1ccc(Cl)cc1Cl +CCOC(=O)C1CCN(C(=O)c2ccc(C)cc2O)CC1 +COCC(=O)OC(C)c1nc2cc(Cl)ccc2s1 +CC(C)OC(=O)C1C(=O)NC2(C)CC1c1ccccc1O2 +CCN(CCc1nccs1)C(=O)c1n[nH]c2ccccc12 +CN1CC(NC(=O)Nc2cc(-c3ccccc3)on2)CCC1=O +Brc1ccc2c(c1)SCc1nncn1-2 +Cc1nn(Cc2nc3ccccc3[nH]c2=O)c(=O)c(C#N)c1C +CCC1(CNC(=O)N2CCN(CCOC)C(=O)C2)CCCC1 +Cc1cc(=O)oc2c3c(ccc12)OCN(Cc1cccnc1)C3 +CCN(CC(C)C#N)S(=O)(=O)c1ccccc1C#N +O=c1c2cnc3c(-c4ccccc4)cnn3c2ccn1-n1cnnc1 +CCN(CC)C(=O)CN(c1cccc(Cl)c1)S(C)(=O)=O +COc1cc(C)c(Cl)c(C)c1-c1c[nH]c(N)c1C#N +O=C(NCc1ccncc1)c1cc(F)ccc1-n1cnnn1 +Cc1nc(-c2ccc(OCc3nc(C4CC4)no3)cc2)no1 +CC(NC(=O)Nc1ccc(Oc2cccnc2)nc1)c1cnn(C)c1 +Cc1ccc2ncc(C(=O)Nc3ccc(NC(=O)NC4CC4)cc3)n2c1 +CC(=O)c1csc(C(=O)N(C)c2nc3ccccc3n2C)c1 +O=C(OCn1nnc2ccccc2c1=O)c1cccc(F)c1 +O=C(OCC(=O)c1c[nH]c2ccccc12)c1ccc(CO)cc1 +CN(CCc1ccccc1)S(=O)(=O)c1cc(F)ccc1F +COCCc1noc(C(C)NC(=O)Nc2ccc(OC)c(C#N)c2)n1 +CC(=O)N(c1nc(CO)cs1)c1c(C)cc(C)cc1C +O=C(OCc1ccccc1)N1CCC2(CC1)NCCNC2=O +CCCNC(=O)N(C)CC(=O)Nc1cccc(F)c1 +C=CCOc1ccc(C(=O)N(CC2CCCO2)c2ccncc2)cc1 +Cc1cc(C)n2nc(C(=O)NC(C)(C)CC(C)(C)C)nc2n1 +N#Cc1c(F)cccc1NCCc1nncn1C1CC1 +Cc1noc(CNC(=O)NC(c2ccccc2F)C2CCCC2)n1 +CC(C)c1nnc(C2CCN(C(=O)C3CCC3)CC2)o1 +CCc1nc(C)c2c(C)c(C(=O)N3CCCCC3)sc2n1 +O=C(NCC#Cc1ccccc1)NCCc1nnc2n1CCC2 +Cc1csc(Sc2ccc(NC(=O)N(C)CCC#N)c(C)c2)n1 +CCc1ccc(C(=O)N2CCCN(c3nnc4ccccn34)CC2)cc1 +CCNC(=O)CN(CC)C(=O)CSc1nc(C)cc(C)n1 +O=c1[nH]nc(-c2cc(C3CC3)n[nH]2)n1-c1cccc(Cl)c1 +CNC(=O)c1ccc(NC(=O)CCOCc2ccccc2)cc1Cl +CC=CC=CC1NCCc2ccc(OC)c(OC)c21 +CCn1ccnc1CN(C)C(=O)c1cn(Cc2ccccc2F)nn1 +Cc1ccc2c(c1)C(c1ccccc1F)=NCC(=O)N2C +CN1CCN2CCN(c3ccc(-c4ccccc4)nn3)CC2C1=O +CS(=O)(=O)NC1CCN(C(=O)c2cnn(-c3ccccc3)c2)CC1 +CCNC(=O)N1CCN(CCSc2ccccc2F)CC1 +COc1cc(C)c(C(=O)N(C)c2ccccn2)cc1OC +COc1ccc(C2CC2C(=O)N2CCCC(c3cc(C)[nH]n3)C2)cc1 +CCOC(=O)Cc1c(C(F)(F)F)nc(N)[nH]c1=O +CC(C)NC(=O)CCS(=O)(=O)c1ccccn1 +CNC(=O)c1ccc(CNC(=O)C2(c3ccc(F)cc3)CC2(C)C)o1 +COc1cc(C)c(NC(=O)CC(C)C)cc1OC +Cc1ccc(NC(=O)CN2C(=O)CCc3ccccc32)nc1 +CCC1C(=O)NCC12CCN(C(=O)OC(C)(C)C)CC2 +Cc1ccc(C(=O)OCC2CC(=O)N(C3CC3)C2)cc1Cl +Cc1cc(OCC(=O)OCC(=O)N2CCCC2)ccc1Cl +COc1c(F)cc(NC(=O)NCc2ccc(F)cc2)cc1F +COc1ccc(CCNC(=O)c2ccc(CC#N)cc2)cc1 +CC1CCCN(C(=O)C(C)Sc2nncn2C)C1 +O=C(NCc1ccccc1)N1CCn2c(Cn3cncn3)cnc2C1 +CC(C)(Oc1ccc(F)cc1Cl)C(=O)n1ccnc1 +O=C(C1CC2C=CC1C2)N1CCc2nnc(Cc3cccnc3)n2CC1 +O=C(CC1CCCCC1)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +CCCNc1nnc(SCC(=O)N2C(C)CCCC2C)s1 +O=S(=O)(c1ccccc1)N1CCN(c2ccccn2)CC1 +CCc1cccc(NC(=O)NC2CC3C(=O)NC(CC)C(=O)N3C2)c1 +COc1cc(OC)c(NC(=O)CCc2ccccn2)cc1F +CCc1nn(C)c(CC)c1CNC(=O)Nc1nnc(C(F)F)s1 +CCSc1cc(C(=O)NCc2ccsc2)ccn1 +N#Cc1ccccc1Cn1c(N)nc2cc(Cl)ccc21 +CCNC1=NS(=O)(=O)c2cc(C(C)(C)C)ccc2N1 +COc1cc(C(=O)Nc2ccccc2O)ccc1C +CCOC(=O)CN(C(=O)Cc1c(C)nn(C)c1C)c1ccc(F)cc1 +COc1cccc(OCc2cc(=O)n3nc(C)sc3n2)c1 +O=C(c1nc2ccccn2c1-c1ccncc1)N1CCCC1 +O=C(NCC(=O)N1CCc2ccccc21)C1COc2ccccc2C1 +Cc1ccc(CNC(=O)CNc2ccc(C(=O)NC(C)C)cc2)cc1 +CCOCC(=O)N1CCCn2c(CN3CCOCC3)nnc2C1 +CS(=O)(=O)NCC1OCC2CN(C(=O)c3ccccn3)CCC21 +CS(=O)(=O)NCCSc1nnc(C2CC2)n1C1CC1 +CCN1C(=O)CCc2cc(NC(=O)c3cccc(C)c3)ccc21 +CCC(=O)Nc1ccc(S(=O)(=O)Oc2ccc(C#N)c(F)c2)cc1 +O=C(CNC(=O)C1CC1)Nc1nc(-c2ccc3c(c2)COC3)cs1 +CCC(O)c1c(-c2ccccc2)nc2c(F)cccn12 +Cc1noc(NC(=O)c2ccc(OCC3CC3)cc2)n1 +CCN(C(=O)c1cc(-c2ccc(O)cc2)n[nH]1)C1CCOC(C)(C)C1 +CCNC(=O)NC(CC(C)C)C(=O)N1CCC(CO)CC1 +Cc1cc(C(=O)N2CCCCC2c2nc3ccccc3n2C)[nH]n1 +Cc1nn(C)c(C)c1CC(=O)NCCNc1cccc(F)c1C#N +CN1C(=O)c2ccccc2NC1C1=CCC2CC1C2(C)C +Cc1noc(CNC(=O)C(C)(C)c2ccc3c(c2)OCCO3)n1 +NC(=O)N1CCCC(C(=O)N2CCC(c3cccc(O)c3)CC2)C1 +CC(C)(C)OC(=O)N1CCNC(c2ccc(F)c(F)c2)C1 +CC(NC(=O)Nc1nccs1)c1cccc(C(F)(F)F)c1 +N#Cc1c(F)cccc1NCCNC(=O)C1CC=CCC1 +CCOc1ccccc1C(=O)NCC(=O)Nc1cc(C)n[nH]1 +COc1ccc(-c2nnc(NC(=O)c3cc(C)n(C)n3)o2)c(OC)c1 +CC(C)(C)NC(=O)c1cc(S(C)(=O)=O)c(Cl)cc1Cl +CC1Oc2ccc(NC(=O)c3ccncc3F)cc2NC1=O +Nc1ncccc1C(=O)N1CCC(n2cccn2)CC1 +CC(Sc1ccccn1)C(=O)N1CC(C)(C)C1(C)C +CC(=O)c1cc(OCc2ccccc2)cc(N)c1O +O=C(NCc1nnc(-c2ccncc2)o1)c1c(F)cccc1Cl +Cc1sc(=O)n(CC(=O)NCCOC2CCCCC2C)c1C +Cn1ccc(-c2nnc(NC(=O)CCCSc3ccccc3)o2)n1 +CC(Sc1ccccc1)C(=O)OCC1CCCO1 +COc1ccc(-n2c(C)nn(Cc3ccc(Cl)cc3)c2=O)cc1 +COC(=O)Cc1nn(-c2ccc(F)cc2)c2c1nnc1ncnn12 +O=C(C#Cc1ccccc1)NCc1cccc(Br)c1 +CC1CCCCN1C(=O)c1cc(C(F)(F)F)n(C)n1 +CCCCn1nc(C(=O)N(C)Cc2cccnc2)ccc1=O +COc1ccc(CC(=O)OCc2cccc(C#N)c2)cc1 +Cc1cccc2nc(COc3ccc(-c4nnco4)cc3)cc(=O)n12 +CCOCCCNS(=O)(=O)c1c(C)nc2sccn2c1=O +Cc1ccc(OCC(=O)Nc2ccc(S(C)(=O)=O)cc2C)c(C)c1 +COCc1ccccc1CNC(=O)N(C)Cc1cc(C)on1 +COc1ccccc1-c1nnc(SCCCc2cnn(C)c2)n1N +C=CCNC(=O)Cn1c(=O)c2c(OC)c(CC)cnc2n(C)c1=O +Nc1ccc(-c2csc(=O)n2CCCO)cc1 +Cc1c(Cl)cc(C(=O)NC(C)Cn2cncn2)cc1Cl +CS(=O)(=O)N1CCCC(C(=O)NCCc2ccccc2)C1 +CC1(C)CN(C(C(=O)NC2CC2)c2ccc(F)cc2)CCO1 +CN(Cc1ccc2ccccc2n1)C(=O)c1n[nH]c2ccccc12 +COc1cccc(S(=O)(=O)Cc2noc(Cc3ccccc3)n2)c1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)Nc3ccc(OC)cc3)ccc21 +Cc1cc(OC(=O)CCNC(=O)c2ccco2)ccc1C(C)C +COc1ccc(CCNC(=O)c2cc(N)c[nH]2)cc1 +Cc1cccnc1C(C)NC(=O)Cn1cc(C)c(=O)[nH]c1=O +Cc1ccc(C(O)C2NCCc3ccc(C)cc32)cc1 +CC(CN1CCCC1=O)NC(=O)c1cccc(N)c1 +Cc1ccc2[nH]cc(C(=O)N3CCC(C)CC3)c(=O)c2c1 +CC(C)NC(=O)CN(C)c1ncc(Br)cc1N +COc1ccc(NS(=O)(=O)Cc2ccccc2Cl)cc1OC +CNC(=O)c1cc(NC(=O)CC(C)(O)c2ccccc2)ccc1F +CC(=O)Nc1nc(C(=O)OC2(C)CCC2)cs1 +CN(C(=O)c1cc(Br)cn1C1CC1)c1ccccc1 +Cc1cnc(C(C)CNC(=O)Nc2cnn(CC3CCCO3)c2)s1 +Cc1ccccc1C(=O)NC(C#N)c1cccnc1 +Cn1nc2n(c1=O)CCN(C1CCc3c(F)cc(F)cc31)C2 +COC(=O)c1cccc(C(=O)NCc2ccc(Cl)cc2Cl)n1 +CCCCn1nc(C(=O)N2CCC(N3CCNC3=O)CC2)ccc1=O +CCN(CCc1ccncc1)C(=O)c1cc(N)ccc1Cl +COc1ccc2[nH]c(=O)c(CCC(=O)NC3CC3)cc2c1 +CC(Nc1cccc(-n2cccn2)c1)c1ccsc1 +COCCOc1ccccc1C(=O)N1CCN(C2CCCC2O)CC1 +CC(=O)Nc1ccc(O)c(C(=O)Nc2ccc(N3CCCC3)nc2)c1 +CCCC(C)N(C)C(=O)Cc1ccc(S(N)(=O)=O)s1 +COc1ccc(C(=O)NC2CCN(c3ncccn3)CC2)c(OC)c1 +CCOc1ccc(C(=O)OCc2csc(NC(C)=O)n2)cc1 +COc1c(C)cc(C)cc1-c1cnn(C)c(=O)c1CC#N +CN(c1ccccc1)c1cc(=O)nc2ccccn12 +CCCNc1nnc(-c2sc(CC)nc2C)s1 +O=C(CSc1ccncc1)Nc1ccc2ccccc2c1 +Cc1cccc(NC(=O)CCCOc2ccc(F)cc2)c1C(N)=O +Nc1ccc(C(=O)Nc2cn[nH]c2)cc1C(F)(F)F +COc1cccc(CNc2c(C)cc(C)cc2C)n1 +CCc1nc(C2CCCN(C(=O)c3cn4cccnc4n3)C2)no1 +Cc1ccc2c(c1)N(Cc1nc(C)cs1)CCCO2 +COCc1nn2c(C#N)c(-c3ccc(N(C)C)cc3)nc2s1 +COc1ccc(S(=O)(=O)N2CC(C)OC(C)C2)c2ccccc12 +COC(=O)CCNC(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +COc1ccc(Cl)cc1N(C)C(=O)C1CCN(C(C)=O)CC1 +CC(C)CN1CCOC(COC(=O)C2CC2c2ccccc2F)C1 +CC(C)(O)CCc1ccc(C(=O)N2CCC3(CCOCC3)CC2)cc1 +Cc1nnc2n1CC(CNc1ncnc3[nH]ccc13)CC2 +CCc1c(NC(=O)N2CCC(O)C2)cnn1CC(C)C +COc1ccc(C)cc1CCNC(=O)c1cccc(-n2cccn2)n1 +CC(C)CCN(C)C(=O)C1CCCN(S(C)(=O)=O)C1 +CC(=O)c1cccc(NC(=O)NCC2CCCC2)c1 +Cn1nccc1CNC(=O)Nc1ccc(N2CCOC2=O)cc1 +CNC(=O)NC(C)(C)C(=O)NCCCC1CCCCC1 +Cc1nc(-c2cccs2)sc1C(=O)NCc1ccco1 +CC(C)NC(=O)C1(NC(=O)c2cc3scnc3[nH]2)CCCC1 +CCOc1ccccc1C(=O)Nc1cc(C)ccn1 +O=C(Nc1ccncc1)N(CC1(O)CCCC1)CC1(O)CCCC1 +Cn1nccc1CCNC(=O)Nc1ccc(OC2CCCC2)c(F)c1 +COc1ccc(NC(=O)c2cc(=O)c3ccc(OC)cc3o2)cc1 +COc1ccc(Cl)cc1NCCC(=O)N1CCCC(C(N)=O)C1 +Cc1nc(CN2CC(N(C)Cc3ccco3)C3OCCCC32)cs1 +COc1ccccc1OCC(=O)Nc1ccc(Cl)cc1N +Nc1nc2cc3c(cc2n1Cc1ccc(F)cc1)OCCO3 +O=C1CCc2c1cnc1nc(N3CCCCC3)[nH]c(=O)c21 +COc1ccc(-c2nc3c(N)cccn3n2)cc1OC +COCC(C)(O)CNS(=O)(=O)c1cc(Cl)ccc1Cl +COC(=O)c1ccc(NC(=O)Nc2ccc3c(c2)nc(C)n3C)cc1 +O=C(NCC1CCCO1)c1ccc(-c2ccc3ccccc3c2)[nH]c1=O +Cc1cc(=O)oc2cc(OCC(=O)N=c3[nH]c4ccccc4[nH]3)ccc12 +CC(=O)Nc1cccc(NC(=O)N(Cc2cccs2)C2CC2)c1C +Cn1nc(CNC(=O)c2cccc(Cl)c2)cc1-c1ccncc1 +Cc1nn2c(nc(N3CCC(C(N)=O)CC3)c3ccccc32)c1Cl +NC(=O)c1ccsc1NC(=O)c1ccc(F)cc1 +CCc1nnc(SCC(=O)Nc2ccccc2NC(C)=O)n1N +CC1CN(C(=O)c2cccc(NC(=O)C3CCCO3)c2)CC(C)O1 +O=C(Cc1csc(NC(=O)c2cccs2)n1)NC1CC1 +CCOc1ccccc1NC(=O)NCCNC(=O)c1cccnc1 +COc1ccc(CCNC(=O)c2cn(CC(=O)N(C)C)nn2)cc1 +COCCN(Cc1ccoc1)C(=O)C1(c2ccccc2)CCOCC1 +Cc1cc(C)c(NC(=O)COC(=O)Cc2ccc(F)cc2)c(C)c1 +Cc1ccc(NC(=O)N(C)CCN(C)C(=O)OC(C)(C)C)cn1 +COc1ccc(S(=O)(=O)C2CCN(C(=O)CC#N)CC2)cc1 +Cc1ccc(C(=O)NCc2ccccc2F)cc1F +CC(C)CNC(=O)c1cccc(NC(=O)C2CCCO2)c1 +CCOc1ccc(NC(=O)N2CCCN(C(=O)CC)CC2)cc1 +Cc1ccc(N2CCC(C(=O)Nc3ccc4c(c3)COC4)C2=O)cc1 +CC(C)(C)NC(=O)c1ccccc1NCC(=O)NC1CC1 +CC1CCCCC1OCCNC(=O)c1cccnc1N1CCOCC1 +CCCCNC(=O)C1COc2ccc(OC)cc2C1 +CCn1cc(NC(=O)NC2CCSc3ccccc32)cn1 +CCC(C(=O)OCC(=O)N1CCCC1)c1ccccc1 +Cc1cnc(CNC(=O)COc2ccc(Cl)cc2Cl)cn1 +COc1ccccc1CC(=O)N1CCCC(c2nc(C)cs2)C1 +O=c1c2sccc2ncn1Cc1ccc2ncccc2c1 +COC(=O)c1cccc(CCNC(=O)c2ncoc2C2CCCO2)c1 +C=CCn1c(SC(C)C(N)=O)nnc1-c1ccc(Cl)cc1 +Cc1ccc(CC(=O)Nc2ccc(N3CCNC3=O)cc2)s1 +NC(=O)c1ccccc1NC(=O)c1ccc(=O)n(Cc2ccccc2)n1 +CNc1nc2c([nH]1)c(=O)n(C)c(=O)n2CCCOC +CN(CCc1ccccn1)C(=O)CCc1cc2ccccc2[nH]c1=O +CCOC(=O)c1ccc(NC(=O)CCn2cnnn2)cc1 +CCOC1CC2(CCN(C(=O)c3cnccn3)CC2)C1 +CC(=O)Oc1ccc(C(=O)Nc2ccc3c(c2)OCO3)cc1 +O=C(c1ccc2nc(N3CCCCC3)sc2c1)N1CCCCC1 +CC(C)c1ccc(OCCC(=O)N2CCCC(C(N)=O)C2)cc1 +COc1cc2c(cc1OC)CN(C(=O)c1ccccn1)CC2 +NC(=O)C(NCC(F)(F)F)(c1ccc(Cl)cc1)C1CC1 +Cc1nc(N)nc(COc2ccc(Cl)cc2Cl)c1C(N)=O +CCc1c(C)c2ccc(OC(C)C(C)=O)cc2oc1=O +COc1cccc(C2NCCc3c2ccc(F)c3O)n1 +Cc1ccc(NC(=O)c2cccn2Cc2noc(C3CC3)n2)cc1 +O=C(Cc1c(F)cccc1Cl)N1CC(c2nc3ccccc3[nH]2)C1 +Cc1ccc(NC(=O)CNS(C)(=O)=O)cc1C +Cc1cc2occ(CC(=O)NCc3ccccn3)c2cc1C(C)C +CSc1ncc(CNC(=O)Nc2ccc3c(c2)CCC3)n1C +CCCCCCSc1ncnc2c1cnn2C +C=CC(C)NC(=O)C1(c2ccc(F)cc2F)CCOCC1 +CS(=O)(=O)N1CCN(Cc2nc(-c3cccs3)cs2)CC1 +O=C(c1cc2cccnn2n1)N1CCN(C(=O)C2CCC2)CC1 +CCc1noc(CC)c1CNS(=O)(=O)CC(C)C +COCC(C)S(=O)(=O)N1CCN2CCCC2C1 +O=C(Nc1ccccc1NCCc1ccccn1)C1CCOCC1 +Cc1ccc(C(=O)NCC(O)c2ccc(C)cc2)cc1 +CC(=O)c1ccc(N2CCN(C(=O)c3cccc(C#N)c3)CC2)cc1 +Cc1nc(Nc2ccc(O)cc2)c2ccccc2n1 +Cc1ccc(CC(=O)Nc2ccnn2C2CCCC2)cc1 +Cc1ccc(Sc2ncccc2C(=O)NCc2cccnc2)c(C)c1 +CCOC(=O)c1ccc(NCc2nnc3ccccn23)nc1 +CC(=O)Nc1ccc(C(=O)N2CCC3(CCOCC3)CC2)cc1C +Cc1ccc2c(c1)NC(=O)C(CC(=O)NC(C)(C)C)O2 +Cc1ccc(-n2ccnc2)c(C(=O)N(C)c2nccs2)c1 +COc1ccc(C(=O)OCc2cc(=O)oc3cc(O)ccc23)cc1F +Cc1ccc(C(=O)CCC(=O)Nc2ccc(N)cn2)cc1 +CCc1nnc(C2CCN(C(=O)c3ccco3)CC2)s1 +Cc1ccnc2nc(C(=O)Nc3ccc(-n4cnnn4)cc3)nn12 +CC(C)Cc1ccc(C(=O)CSc2nncn2C2CC2)cc1 +CCCNC(=O)c1cccc(NS(C)(=O)=O)c1C +CCCOc1ccc(C2CC(=O)Nc3c2c(C)nn3C)cc1OC +Cn1cc(NC(=O)NC2CCCN(c3ccccc3Cl)C2=O)cn1 +CCn1c(SCCCO)nnc1-c1ccc(OC)cc1 +CCOc1ccc(-n2nnc(C#N)c2-c2cccc(F)c2)cc1 +Cn1cncc1C1NCCc2cc(Cl)c(Cl)cc21 +COc1ccc2c(c1)sc1nc(C)c(CCO)c(=O)n12 +Cc1cnn(CCC(=O)Nc2ccc3[nH]c(-c4ccccn4)nc3c2)c1 +Cc1cc(C)n2c(C(=O)N(C)C3Cc4ccccc4C3)nnc2n1 +Cc1cn2c(CNc3cccc(NC(=O)C(C)C)c3)c(C)nc2s1 +COc1ccc2[nH]cc(CCNC(=O)c3cc(C4CC4)[nH]n3)c2c1 +C=C(C)CN(CC)C(=O)NCc1ncc(CC)s1 +COCC1CN(Cc2cccs2)Cc2nn(C)cc21 +CC(C)(C)OC(=O)N1CCNCC1c1ccc2ccccc2c1 +CN(CC(=O)NC1CC1)C(=O)c1ccc(F)cc1 +Cc1cc(C(=O)N(C)c2ccc(Cl)cn2)no1 +COc1cc(NC(=O)c2ccc(C(=O)N(C)C)cc2)cc(OC)c1 +CCC(CC)CNC(=O)C(N)c1ccc(F)cc1C +Cn1ccnc1SCC(=O)NC(C)(C)CC(C)(C)C +CC(C)N(CCCNc1ncc(C#N)cc1Cl)S(C)(=O)=O +FC(F)n1c(CN2CCN(c3ncccn3)CC2)nc2ccccc21 +CC(CNC(=O)Nc1ccnn1C)Oc1cccnc1 +COc1c(F)ccc2c1C(C(O)c1ccccc1)NCC2 +COc1cc(OC)cc(C(=O)N2CCC(O)(c3cccnc3)CC2)c1 +Cc1c(C(=O)N(C)CCc2ccccc2)cnn1-c1ccncc1 +Cc1ccc(OCC(=O)NCc2nc(-c3cccs3)no2)cc1C +COc1ccc(C(=O)NCC(C)(OC)c2ccccc2F)cc1F +Cc1nc(CC(=O)NC2Cc3ccccc3C2)cs1 +Cc1nsc(N2CCCN(Cc3cccn3CCC(C)C)CC2)n1 +O=C(NCCCO)c1ccc2c(c1)Cc1ccccc1-2 +Cc1ccc(NC(=O)N(C)Cc2ccncc2)c(F)c1 +Cc1nc(-c2cc3ccccc3o2)sc1C(C)O +COc1cc(C)ccc1NC(=O)c1ccn(-c2ccc(F)cc2)n1 +O=C(NC1CCOC1c1ccccc1)c1c[nH]c2cccc(F)c12 +NC(=O)c1ccc(S(=O)(=O)Nc2cccc(CO)c2)cc1 +O=C(COC(=O)c1cccc(F)c1)NCc1ccccc1F +CC(C)C1CN(C(=O)CCn2ccccc2=O)c2ccccc2N1 +CN(CCNC(=O)Nc1nnc(C(F)(F)F)s1)c1ccccc1 +CC1CCCC(C)N1C(=O)c1cc(-c2cccs2)on1 +Cc1c(CC(=O)NCCCOC(C)C)c(=O)oc2cc(O)ccc12 +NC(=O)c1ccsc1NC(=O)COc1cccc(Cl)c1Cl +CCc1n[nH]c(C2CN(C(=O)CCCc3nc(CC)no3)CCO2)n1 +O=C(Nc1ccc(OC(F)F)cc1)C1CC(=O)N(C2CCCC2)C1 +CS(=O)(=O)NCC#CCOc1ccccc1Cl +COc1ccccc1N1CCN(c2cc(C)c3nc(N)nn3c2)CC1 +CCCS(=O)(=O)N1CCC(n2cc(Cc3ccccc3)nn2)CC1 +CNC(=O)COC(=O)c1sc2nc3n(c(=O)c2c1C)CCCCC3 +COc1ccc2c(CNc3ccccc3)cc(=O)oc2c1 +Cc1ncc(C(C)NCc2cccnc2OCc2ccccc2)s1 +CCN(CC1CC1)C(=O)Cc1cccc(OCC#N)c1 +CCC(CC)N(C)S(=O)(=O)c1ccc(OC)c(C(N)=O)c1 +Cc1ccc(NS(=O)(=O)c2ccc(-c3onc(C)c3C)o2)nc1 +CCN(C)c1ccc(C(=O)NCc2ccc(-n3cccn3)nc2)cc1 +Cc1cc(C(=O)N(C)c2ccc3c(c2)CCO3)[nH]n1 +Nc1ccc(C(=O)CN2CCN(c3cccc(Cl)c3)CC2)cc1 +COC(=O)c1ccc(Cl)cc1OCC(=O)Nc1cc(C)on1 +c1ccn2c(CNc3nccc(C4CCCC4)n3)cnc2c1 +CCOc1ccc(OC)c(-c2cnn(C)c(=O)c2N)c1 +Cc1cc(NCCNS(=O)(=O)c2cccc(Cl)c2)nc(C)n1 +Cc1cccc(OC(C)C(=O)Nc2cc(N)ccc2C)c1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1cc2ccccc2s1 +CC(O)CN1CCN(C(=O)c2ccc(OC(C)C)nc2)CC1 +CCCCNC(=O)c1onc(-c2cccc(C)c2)c1N +COc1ccccc1NC(=O)Nc1c(C)ccc(N)c1C +CCc1nc(CC(=O)Nc2cc(OC)cc(OC)c2)cs1 +O=C(NCc1ccccc1Cl)C1CCCN(c2cn[nH]c(=O)c2)C1 +NC(=O)C1(CNC(=O)Nc2cccnc2-n2cccn2)CCOCC1 +CCOc1ccc(NC(=O)Nc2cnn(CC3CCCO3)c2)cc1 +CCn1c(SCC(=O)c2ccc[nH]2)nc2ccccc2c1=O +COc1cc(C(C)NC(=O)c2cc(C)on2)ccc1OC(C)C +Cn1ncc(Cl)c1C(=O)Nc1ccc2c(c1)OCCO2 +Cc1nc(CC(=O)OCC(=O)NC2CCCCC2C)cs1 +CC(Sc1nnc(NC2CC2)s1)c1nc2ccccc2c(=O)[nH]1 +O=S(=O)(c1ccc2c(c1)OCCO2)C(F)F +CCCc1cc(NC(=O)c2scnc2C2CC2)n[nH]1 +CC(=O)c1ccc(S(=O)(=O)NC2CCOC2=O)cc1 +Cc1noc(C)c1C(=O)N1CCCC1c1ccccc1F +Cc1ccc(NC(=O)NC=Cc2ccsc2)cc1 +Cc1ccc(OCCn2nnc3ccccc32)cc1 +CCNc1nc2ccc(C(=O)OCC)cc2s1 +CC(NC(=O)CSc1ncc(-c2ccccc2)o1)C1CC1 +Cc1cc(C(=O)N2CC(CO)OCC2C)c(C)cc1Br +CCOC(=O)C(C)(NC1CC1)c1cc(F)ccc1F +NC(=O)OCCNC(=O)C12CC3CC(CC(F)(C3)C1)C2 +CC(C)(C)NC(=O)N1CCC(CNC(=O)c2ccc(C#N)cc2)CC1 +CCOC(=O)c1nn(-c2nccs2)c2[nH]c(=O)cc(C)c12 +O=C(Nc1cccc(Cn2ccnc2)c1)c1cc2c(F)cccc2[nH]1 +O=C(CNC(=O)c1cccnc1)c1ccc2c(c1)CCCC2 +COc1ccc(-c2csc(NC(=O)Cn3ccnc3)n2)c(OC)c1 +CN(CCc1cnn(C)c1)c1cc(-c2ccccc2)nc2ccnn12 +O=C(NCCCOC1CCCc2ccccc21)c1cnccn1 +Cn1cc(CN(C(=O)c2ccccc2N2CCOCC2)C2CC2)cn1 +CC(OCc1ccccc1)C(=O)N(C)CC(=O)NC1CC1 +CC1CCC(NC(=O)C2(c3ccc(F)cc3F)CCOCC2)CC1 +CCN(CC)C(=O)CCCNc1ncnc2sc3c(c12)CCCC3 +Cc1csc(N2CCN(Cc3nnc(C)n3C)CC2)n1 +O=C(c1ccc(Br)cc1)N1CCC2(O)CCCCC2C1 +CCCn1nccc1NC(=O)CCC(=O)c1ccc(C)cc1 +Cc1cc(Cl)cc2c(CC#N)c3c(nc12)CCN(C)C3 +Nc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1 +CCCN(CCO)C(=O)Nc1ccc(C(=O)NC2CCCCC2)cc1 +Cc1n[nH]cc1CN1CCN(CC(=O)NC2CCCCC2)CC1 +Nc1cc(C(F)(F)F)ccc1OCc1ccco1 +Cn1cc(Br)c(-c2nnc(-c3ccccc3)o2)n1 +COCc1noc(Cn2ccc3ccc(Cl)cc32)n1 +Cn1c(=O)n(C)c2cc(NC(=O)c3ccco3)ccc21 +CCOC(=O)CSc1ccc(C(F)(F)F)cc1C#N +COC(=O)c1snc(-c2ccc(F)cc2)c1N +CCC(C)Oc1cccc(-c2cc(N)c(=O)[nH]n2)c1 +O=C(NCC1CCN(C(=O)Oc2ccccc2)CC1)c1ccsc1 +CCCOc1ccccc1OCC(=O)Nc1ccccc1O +O=C(COc1cccc(-n2ccnc2)c1)Nc1cc(F)ccc1F +CC(=O)NC(C)c1nc2ccccc2n1CCC(C)C +CC1CCN(C(=O)CSc2nnc(-c3ccccn3)o2)CC1 +COc1cccc(C(O)CCC(=O)NC2CCCC2)c1 +O=C(CSc1ccncc1)NCCc1ccccc1Cl +CC(C)Cc1ncc(CNC(=O)N2CCCCC2c2cn[nH]c2)s1 +COc1ccccc1OCC(=O)N1CCNC(=O)C1c1ccccc1 +CNc1nc(C)c(C(=O)NCC(=O)Nc2ccc(C)cc2F)s1 +CC(C)NC(=O)c1ccccc1NC(=O)Cc1ccc(F)cc1 +CC1CC1NC(=O)c1cccc(OCc2ccccc2C#N)c1 +O=C(NCc1ccc(S(=O)(=O)NC2CC2)cc1)C1CC2CCC1C2 +COc1ccc(CCSc2ccc(NC(C)=O)cc2)cc1 +Cc1csc(SCC(=O)Nc2cc(C)nn2C(C)(C)C)n1 +CC(C)c1ncc(Cl)c(C(=O)N=c2sccn2C)n1 +O=C(NCc1cn(-c2ccccc2)nn1)C1(c2cccc(F)c2)CC1 +COc1ccc2[nH]cc(C3CCN(S(=O)(=O)N(C)C)CC3)c2c1 +Cc1nc(N(C)C)ncc1C(=O)NCC1COc2ccccc2C1 +N#CC(NC(=O)c1cnc(C2CCCO2)s1)c1cccc(Cl)c1 +Cn1c(C(=O)NCCCN2CCOCC2)cc2ccc(Cl)cc21 +O=C(Nc1ccccc1)c1c[nH]c2cccc(F)c12 +N#Cc1cc(-c2ccc(Br)cc2)n(CCO)n1 +CCn1cnnc1CNC(=O)c1sccc1C1CC1 +COC(=O)C1(NC(=O)c2cccnc2)CCCCCC1 +COCCOc1cccc(CN2CCOC(c3cnn(C)c3)C2)c1 +CC(=O)N(C)C1CCN(C(=O)c2cccc(-c3n[nH]c(C)n3)c2)CC1 +COCC(=O)N1CCN(Cc2nc(-c3cccs3)no2)CC1 +c1ccc(-c2cnc(Cn3nnc(-c4ccsc4)n3)o2)cc1 +N#Cc1ccc(NCCOc2ccc(Cl)cn2)nc1 +COC(=O)c1ncn(CC(=O)N2CCCc3ccccc32)n1 +Cn1nnnc1SCC(=O)N1CCc2sccc2C1 +CC(C)c1nnc(NC(=O)c2cc(-c3cccs3)on2)s1 +CN(c1ccccn1)S(=O)(=O)c1cc(Cl)ccc1Cl +CC(C)CCNC(=O)C1CCCN(c2cnc3nccnc3c2)C1 +Cc1ccccc1C(=O)OCC(=O)NCc1ccc(Cl)cc1 +Cc1ncn(CC(=O)N2Cc3cncnc3C2)c(=O)c1C +O=C1CCc2ccc(NS(=O)(=O)c3ccc(F)cc3)cc2N1 +CCC1c2ccsc2CCN1C(=O)c1cc(F)cc(F)c1 +CCc1nnc(NC(=O)NC2CCCC(CC)C2)s1 +O=C(Nc1cccc2cccnc12)N1CCC(O)C1 +COc1ccc(C(CO)N(C)Cc2nc(N)c3ccccc3n2)cc1 +Cn1ncc2c(Nc3cccc(C(F)(F)F)c3)ncnc21 +Nc1ccc(C(=O)c2cc(C(F)(F)F)ccc2O)cc1 +CCCOc1ccc(C(C)NC(=O)c2ccc(F)nc2)cc1OC +O=C(CCc1nc(-c2ccccc2F)no1)NCc1ccco1 +CC(C)c1nc(CNc2cccc(N3CCCC3=O)c2)cs1 +N#CC(C(=O)c1cnn(-c2ccccc2)n1)c1ccccn1 +Nc1cc(C(=O)N2CCCCCC2)nn1-c1ccc(F)cc1 +CCn1nc(C)c(NC(=O)c2cccc(C)c2)c1C +Clc1cc(Cl)cc(CN2CCC3(C2)OCCO3)c1 +CC(C)Oc1ccccc1NCc1ccc2c(c1)OCCO2 +O=c1cc(C2CCC2)ncn1Cc1csc(-c2ccc(F)cc2)n1 +CCOC(=O)c1sc(C(N)CO)nc1C(F)(F)F +CC(C)CNS(=O)(=O)c1ccc2c(c1)CCN2 +Cn1cnc(CNC(=O)N2CCN(c3ccccc3C#N)CC2)n1 +CC(C)(CO)NC(=O)CCOc1ccccc1Cl +O=C(CSc1nc2cc(Cl)ccc2o1)N1CCCC1 +CCCC(=O)N1CCCC(C(=O)Nc2nc(C3CC3)cs2)C1 +CCNC(=O)N(Cc1cccnc1)Cc1ccccc1C +COc1cc(C(C#N)CC(=O)NC(C)C)cc(OC)c1OC +O=C(CC12CC3CC(CC(C3)C1)C2)Nc1cc[nH]n1 +CCc1ccc(C(=O)Cn2cnc3ccsc3c2=O)s1 +CCCn1c(C)nnc1SC(C)C(=O)NC1CCCC1 +COC(=O)C(Nc1cccc(Br)c1)c1cnn(C)c1 +Cc1nc(C(=O)NCc2ccccc2F)cs1 +O=S(=O)(c1ccccc1)N1CCN(CC(F)(F)C(F)F)CC1 +O=C(CCc1ccccc1O)NCCNC(=O)C1CC1 +N#CCOc1cccc(CC(=O)N2CCSc3ccncc32)c1 +CCNC(=O)C1CC(=O)N(c2ccccc2Cl)C1 +CCN(CC(=O)NC(C)C)C(=O)c1sccc1SC(F)F +Cc1cccc2cc(COC(=O)C3CCCO3)c(=O)[nH]c12 +NC(=O)CN1C(=O)CSc2ccc(C(=O)N3CCCCC3)cc21 +CCOC(=O)C=C(C)NC(=O)c1ccc(Br)cc1 +CCOC(=O)C(N)Cc1nc2cc(O)ccc2n1C +CCn1c(C(=O)NCCC(=O)N(C)C)cc2ccccc21 +Cc1ccc(NC(=O)c2ccc(-n3cccn3)cc2)c(F)c1 +CC(=O)NC1(C(=O)Nc2ccc(F)c(N3CCCC3=O)c2)CCCC1 +CC(C(=O)Nc1ccn(-c2ncccc2Cl)n1)c1cccnc1 +Cc1ccc(-c2ncco2)cc1NC(=O)CCCC(=O)NC(C)C +COC(=O)CCCN(C)S(=O)(=O)c1ccc(F)c(Cl)c1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)N(C)C)CC2)c(C)c1 +CCN(CC)C(=O)NCc1ccccc1-n1ccnc1 +CCC(=O)NCC(=O)NCc1ccc(S(C)(=O)=O)cc1 +CN(Cc1ccc(-n2cncn2)cc1)Cc1nc2ccccc2n1C +COc1cc(COc2cccc(N)c2)cc(OC)c1OC +Cc1cc(C(=O)Nc2ccn(C)n2)c2ccccc2n1 +CCOC(=O)c1cccc(NC(=O)c2ccc(S(C)=O)cc2)c1 +Cn1c(NC(=O)C2COCCO2)nc2cc(Cl)ccc21 +CC(C)CNC(=O)C1CCCN1C(=O)c1cc2cnsc2s1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccco1 +CCCNC(=O)CN(C)S(=O)(=O)c1cn[nH]c1C +Clc1ccc(-c2noc(CSc3nc(C4CC4)n[nH]3)n2)cc1 +CC(C)(C)c1cc(C(N)c2cccs2)c(=O)[nH]n1 +CCN(Cc1nc(C)no1)C(=O)C1CC(=O)N(Cc2cccnc2)C1 +Cc1sc(NC(=O)c2cccnc2N2CCOCC2)c(C#N)c1C +CCSc1cc(C(=O)N(C)Cc2ccc(OC)cc2)ccn1 +CC(O)CNC(=O)c1csc(-c2cc3ccccc3[nH]2)n1 +COC(=O)N(C)Cc1cc(C#CCCO)cs1 +CCOC(=O)C1CCN(c2ncnc(Nc3nccs3)c2N)CC1 +O=C1Sc2ccc(S(=O)(=O)N3CCCCC3)c3cccc1c23 +NC(=O)NCc1ccc(C(=O)Nc2cccc(Br)c2)cc1 +CSc1nnc(SCC(=O)Nc2cccc(F)c2)s1 +Fc1cccc(CN(Cc2ccncc2)Cc2cccnc2)c1 +O=C(NCCNc1ccc2n[nH]c(=O)n2n1)c1ccc(Cl)cc1 +CCS(=O)(=O)n1ncc(Cl)c(Cl)c1=O +CCOc1ccc(C(=O)Nc2ccccc2O)cc1OCC +O=C(OCCNc1cccnn1)c1cccc(-c2ccoc2)c1 +Cc1sc(=O)n(CC(=O)NC(C)c2ccccc2Cl)c1C +CC(=O)Nc1cc(NCc2c(F)cccc2F)ccc1C +CN1CCOc2ccc(S(=O)(=O)NCc3cccs3)cc21 +Cn1c2ncccc2c(=O)n1CC(=O)NCc1cccs1 +Cc1cc(NC(=O)NCC2(c3ccccc3Cl)CCOCC2)on1 +CC(NC(C)c1ccc(C(F)(F)F)cc1)C(N)=O +C#CCn1nnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)n1 +CN(Cc1cccnc1)S(=O)(=O)c1ccc(F)cc1F +O=C(NCCCn1cccn1)c1ccc(Cl)cc1O +CCc1ccc(C(=O)NCc2ccnc(C)n2)cc1 +CC1CCC(C(=O)Nc2cc3c(=O)[nH]cnc3cc2F)O1 +Cc1cnc(CNC(=O)CCC(=O)c2ccc(F)c(F)c2)s1 +Nc1nccc(-c2ccc(OC3CCCC3)cc2)n1 +CCCNC(=O)NCc1ccc(OC(C)C)nc1 +CCCC(=O)NCC(=O)NC(C)c1c(C)nn(C)c1C +CCOc1ccc(C2=CCN(C(=O)CCN3CCCC3=O)CC2)cc1 +CC(C)CN1CC(C(=O)Nc2ccc3c(c2)OCCCO3)CC1=O +NC(=O)c1ccc(C(=O)NC23CC4CC(CC(C4)C2)C3)s1 +COc1ccc(C2COc3cc(O)ccc3C2)c(OC)c1O +CN1CCOC(C(=O)Nc2ccn(-c3ncccc3Cl)n2)C1 +O=C(NCc1nnnn1-c1ccc(F)cc1)c1ccc2c(c1)OCO2 +CCn1cc(C(=O)NC2CC3(CCCC3)Oc3ccccc32)c(C)n1 +CC(C)n1nccc1NC(=O)N1CCc2ccccc2C1 +CC(=O)Nc1cccc(COC(=O)COC2CCCCC2)c1 +O=C1CC(c2ccc3cccc(O)c3n2)c2c[nH]nc2N1 +CC(Sc1nnc(C2COc3ccccc3O2)o1)C(N)=O +CC1COCCN1CC(=O)Nc1sc2c(c1C#N)CCCCC2 +CCS(=O)(=O)N(C)CCCNC(=O)N1CCC1 +Cc1cnn(CC2CCCCN2C(=O)c2cnc(C3CC3)s2)c1 +CSc1cccc(NC(=O)C2COc3ccccc3O2)c1 +C=CCNS(=O)(=O)c1cc(C(=O)C(C)C)ccc1F +O=C(c1ccnnc1)N1CCC2(CC(Oc3ccccn3)CO2)C1 +O=C1CN(C(=O)c2ccc(Cl)cc2Cl)CCN1 +Brc1ccccc1-n1cc(NCC2=CCCOC2)cn1 +Cc1nc(C(=O)N=c2[nH]c3ccccc3[nH]2)cc(-n2cccn2)n1 +Cn1ncc2c(N3CCCC3)nc(N3CCCCCC3)nc21 +O=C(CNS(=O)(=O)c1cccc(F)c1)OC1CCCCC1 +Cn1ccsc1=NC(=O)C1CCN(c2ncccn2)CC1 +CCOCCNC(=O)N1CC=C(c2ccc(OCC)cc2)CC1 +O=C(OCc1noc(-c2ccc(F)cc2)n1)c1cscn1 +Cc1cn2c(CN(C)C(=O)c3cc(C(C)(C)C)n[nH]3)c(C)nc2s1 +CCCCCc1ccc(NC(=O)c2ccc(=O)n(C)n2)cc1 +CCn1cc(CNc2nc3ccc(OC)cc3s2)c(C)n1 +CC1N=C(c2ccccc2F)c2ccccc2NC1=O +CC(c1ccc(F)cc1)N(C)C(=O)CN1CCN(CCO)CC1 +CC(C#N)CN(C)CC(=O)Nc1cc(C(C)(C)C)no1 +CC(C)NC(=O)Cn1c(CCNC(=O)C2CC2)nc2ccccc21 +CCC1(CNC(=O)NCC2CN3CCCCC3CO2)CCC1 +COc1ccc(NC(=O)c2ccco2)c(N2CCN(C(C)=O)CC2)n1 +CCN(CC)C(=O)C12CCC(=O)N1c1ccccc1S2 +COc1ccc(NC(=O)CNc2cc(F)ccc2F)cc1 +COc1ccc(C(=O)Nc2c(C)nc3sccn3c2=O)c(OC)c1 +COCc1cccc(C(=O)Nc2cccc3cccnc23)c1 +CC1(C(=O)N2CCC(O)CC2)Oc2ccc(Cl)cc2NC1=O +COc1ccc(OC)c(C(C#N)CC(=O)Nc2ccccc2)c1 +CCn1c(Cn2ccnc2)nnc1C1CCN(c2nccs2)CC1 +N#Cc1cnn(-c2ncnc3sc4c(c23)CCCCC4)c1N +CC1CCC(NC(=O)CCn2ccccc2=O)CC1 +O=C(NCCc1ccccc1)c1ccn(COc2ccc(F)cc2)n1 +CC(=O)c1c(F)ccc2c1nc(C(F)(F)F)n2C +CCc1sc(C(=O)OCc2ccc(C(N)=O)cc2)cc1C +CN(C(=O)C1CC=CCC1)C1CCc2ccccc21 +Nc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1 +Fc1ccccc1CN1CC(c2nc(-c3cccs3)no2)C1 +COc1ccc(NC(=O)COc2ccccc2F)c(OC)c1 +Cc1cc(=O)nc2c3ccccc3n(C(C)C(=O)NC(C)C)n12 +CC1CCCN(c2ncnc(N(CCC#N)CCC#N)c2N)C1 +CCNC(=O)CS(=O)(=O)NC1CCC(C)CC1 +COCCCNC(=O)c1cc(-c2ccc(OC)cc2)c(C)s1 +CNC(=O)C1CCCCN1C(=O)Cn1cnc2ccc(F)cc2c1=O +O=C(c1ccco1)N1CCN(C(=O)C2CC=CC2)CC1 +O=c1c2cccnc2ncn1Cc1cccc2[nH]ccc12 +Cc1cc(C(=O)NCC(=O)NCc2cnn(C)c2C)c(C)o1 +CNC(=O)COC(=O)c1sc(-c2cccc(Cl)c2)nc1C +CCC1CCCCN1C(=O)C(C)Sc1nnc(NC2CC2)s1 +Cc1cccc(-c2nc(-c3ccc4c(c3)oc(=O)n4C)no2)c1 +COc1cc(OC)c(NC(=O)Cc2ccc(F)c(F)c2)cc1F +COc1cc(C(=O)NCc2nc(C)cs2)ccc1OCC(C)C +CCC(=O)OCC(=O)c1c(N)n(C)c(=O)n(C)c1=O +CC(=O)NC1CCCN(C(=O)CSc2ncc3ccccn23)C1 +CC(CC#N)N1CCN(CCOc2ccccc2)CC1 +O=C(NCC1CC1)Nc1ccc(Br)cc1 +COc1cc(CNC(=O)c2cccc(C#N)c2)ccc1OC(F)F +Cc1ccc(Cn2nnc3cc(CO)ccc32)cc1 +Cc1nn(C)c(-c2ccc3c(c2)C(C)(C)C(=O)N3C)c1N +Cn1cc(C(=O)N2CCC(c3nnc(-c4ccco4)s3)CC2)nn1 +Cc1cc(C(=O)NCC(=O)NCCc2ccccc2F)nn1C +CCc1cc(NCc2nncn2CCOC)ncn1 +Cc1occc1-c1nnc(SCC(N)=O)n1C(C)C +COc1ccccc1C(=O)OCC(=O)Nc1c(F)cccc1F +Cc1nc(C)c(C2NCCc3cc(C)c(F)cc32)s1 +CCCN(C)c1ccc(C(=O)OC2CCOC2=O)cc1 +COCc1cccc(CNC(=O)c2ccnc(C)n2)c1 +O=C(Nc1nc2c(s1)CN(C(=O)C1CCCC1)CC2)c1ccoc1 +Cc1ccc(C(=O)CCC(=O)Oc2cccc(-n3cccn3)c2)s1 +Cc1noc2nc(C3CC3)cc(C(=O)NCc3n[nH]c4c3CCC4)c12 +COCCN(C(=O)CCc1ccc(F)c(F)c1)C1CC1 +OCCCN(Cc1ccc(F)cc1)c1ccccc1 +c1ccc(Cc2nc(CNc3ccc(-n4cncn4)cc3)no2)cc1 +Cn1nc2n(c1=O)CCN(C(=O)c1ccc(F)c(Cl)c1F)C2 +O=C(Cc1ccccc1F)N1CCC(Nc2ncnc3c2CCC3)C1 +Cc1ccc(CN(C)C(=O)c2nccnc2N)s1 +Cc1ccc(CCN2CC3(CCOC3)CCC2=O)o1 +COCCOc1ncccc1NC(=O)c1cnn(C2CCCCC2)c1 +C#CCCN1CCN(C(=O)Nc2nc(C)cs2)CC1 +CCOC(=O)Cc1ccccc1NC(=O)C1CC=CCC1 +CC1CC(c2ccccc2)n2nc(NC(=O)c3cccnc3)nc2N1 +COc1cccc2c(C#N)c3c(nc12)CCN(C)C3 +CNC(=O)c1ccccc1OCCCS(=O)(=O)c1ccccc1 +CNC(=O)c1cc(S(=O)(=O)NCc2cccnc2)cs1 +CC(C)(C)C(=O)c1cn(CC(=O)N2CCOCC2)c2ccccc12 +O=C(NCc1cccc(O)c1)Nc1nc(-c2ccncc2)cs1 +Cc1c(NC(=O)Cn2ccc3ccccc32)c(C(=O)N(C)C)nn1C +CCCSc1nc2ccccc2n1CCOC +COc1ccc(C(C)=O)c(OC(=O)CCC(C)(C)C)c1 +CCCOCC(=O)NCc1noc(-c2ccco2)n1 +Cn1c(SCC(=O)c2c[nH]c3ccccc23)nnc1C(F)(F)F +CCC(=O)c1ccc(OCC(=O)Nc2ccc3c(c2)COC3)cc1 +CCOC(=O)NCC(=O)NC(C)c1ccc(Br)cc1 +C#Cc1cccc(NC(=O)Cc2cccc(F)c2F)c1 +O=C(NCCNC(=O)c1ccccc1O)NCc1cscn1 +CC(=O)c1cccc(NC(=O)COc2cc(F)c(F)cc2F)c1 +Cc1ccc(NC(=O)CCSc2ccccn2)cc1C(N)=O +CCC(CC)C(=O)NC(C)c1ccc(S(C)(=O)=O)cc1 +COc1cc(CNc2cccc(N3CCCC3=O)c2)cc2c1OCO2 +CCCc1cc(C(=O)N2CCCC(c3cc(=O)[nH]c(C)n3)C2)[nH]n1 +CN(CC(F)(F)F)C(=O)CSc1ncc(-c2ccc(F)cc2)o1 +CCn1ccnc1SCc1ncnn1CC(C)C +CC(C)(C)n1ncc2c(=O)n(CC(=O)Nc3ccccc3)cnc21 +CC(C)(C)C(=O)Nc1ccccc1C(=O)NCCc1cscn1 +Cc1ccc(C(=O)NCC(=O)N(C)C(C)C)cc1C +COc1ccc(F)c(NC(=O)c2cccc(OC)c2OC)c1 +CCCNC(=O)c1ccc(S(=O)(=O)N2CC(C)OC(C)C2)cc1 +CNC(=O)c1cccc(CNC(=O)CC(C)c2ccccc2F)c1 +COc1cc(O)ccc1CNc1ccc(C)cc1O +O=C(CNC(=O)C1CC1c1ccccc1C(F)(F)F)NC1CC1 +CN(Cc1ccccc1)S(=O)(=O)c1ccccc1S(C)(=O)=O +CCOCCNS(=O)(=O)c1c(NC)nc2sccn12 +CC(Cc1ccc(O)cc1)NC(=O)Nc1nnc(C(F)(F)F)s1 +CCn1c(Sc2cnc3ccccc3n2)nnc1N1CCOCC1 +CC(=O)N1CCC(c2nccnc2Oc2ccc(C(N)=O)cc2)CC1 +CCC(C)CSc1nnc2cc(C)nc(C)n12 +Cn1cc(NS(=O)(=O)c2ccc(N3CCCC3=O)cc2)ccc1=O +CCC(C)C(NC(N)=O)C(=O)NCC1(c2ccccc2)CCC1 +C=CCNC(=O)C1(C)Oc2ccc(C)cc2NC1=O +CC(C)n1c(SCC#N)nc2cc(Cl)ccc2c1=O +CC(NC(=O)c1ccc2[nH]cnc2c1)c1cccc(N2CCCC2)c1 +CCN(CC)C(=O)Cn1nnc(C(C)=O)c1-c1ccccc1 +CCCNc1c(C(=O)OCC)c(=O)[nH]c2ccc(Cl)cc12 +O=C(c1ccccc1F)N1CCC(c2nnc3n2CCCCC3)CC1 +CC(OC(=O)CCc1nc(-c2ccsc2)no1)c1ccccn1 +CC1CCN(C(=O)c2nnn3c2c(=O)[nH]c2cc(F)ccc23)CC1 +COc1cc(OC)c(CCNc2cc(C)nc3ncnn23)c(OC)c1 +CC(=O)c1[nH]c(C)c(C(=O)Nc2ccc(C)c(Cl)c2)c1C +O=C(NCC1CN2CCCCC2CO1)c1ccc(-n2cccn2)cc1 +O=C(NC1CC(O)C(CO)C1)c1ccc(F)cc1 +Cc1cc(C)cc(N(C)C(=O)C2CC(=O)N(C)C2c2cccnc2)c1 +CCC(C)NC(=O)c1cn(-c2ccc(C)c(C)c2)nn1 +O=C(Nc1ccc(F)cc1)N1CCN(C(=O)c2ccco2)CC1 +Cc1ccc(NC(=O)CCc2ccc(F)cc2)nc1 +CN(C)c1ccccc1-c1ccc(-n2cnnc2)nc1 +CNc1nc(-c2sc(C3CC3)nc2C)cs1 +O=c1[nH]c(NCCO)nc2ncn(Cc3ccccc3)c12 +CC(C)n1ncc2cc(NC(=O)C3(C)CC3(Cl)Cl)cnc21 +CC(C)NC(=O)N1CCC2(CC1)C(c1ccccc1)CC(=O)N2C +O=c1c2n[nH]c(=O)n2c2ccccc2n1-c1ccccc1 +CCC(c1ccccc1)c1nnc(NCc2cnc3cnccn23)o1 +Cc1ccc(-c2cc(C(=O)NCc3c(C)nn(C)c3C)no2)cc1 +COc1cc(N2CC3CCC(C2)N(Cc2cscn2)C3=O)ncn1 +O=C(Cc1ccsc1)N1CCC2C1CC(=O)N2CC1CC1 +CCCNC(=O)CNc1nc(C)nc2sc3c(c12)CCC3 +CCCCOc1ccc(C2NC(=O)c3ccccc3N2)cc1OC +O=C(c1ccc[nH]c1=O)N(Cc1ccco1)C1CC1 +CNS(=O)(=O)c1cc(C(=O)NC2CCCCNC2=O)n(C)c1 +C#CCC(C)(C)COC(=O)c1cc(C(C)=O)cn1C +CCn1ccc(-c2ncnn2-c2ccc(C(F)(F)F)cc2)n1 +CC(C)S(=O)c1ccc(C(=O)OCC(=O)N2CCCCC2)cc1 +O=C(NCCN1CCOCC1)c1cccc(OCC(F)F)n1 +COc1ccc(CCC(=O)Nc2ccc3c(c2)OCO3)cc1OC +Cc1onc(-c2ccncc2)c1C(=O)NCCCOC(C)C +Cc1nnc(CN2CCN(c3ccccc3)CC2)o1 +N#Cc1ccsc1C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +CC1CN(C(=O)Cc2csc(N3CCCC3=O)n2)C(C)CO1 +CCNC(=O)C1CCN(C(=O)Nc2ccc(C)c(C)c2)CC1 +COc1ccc(C=Cc2ccn(CCCC#N)c(=O)c2)cc1 +COC(=O)C(CO)NCc1ccc(C(C)C)cc1 +CCOC(=O)C1=C(C)N(C)C(=O)N(C)C1c1csc(C(C)C)n1 +Nc1ccc(C(=O)c2cc(Cl)c(O)c(Cl)c2O)cc1 +O=C(Nc1ccc(F)c(F)c1)c1cccc(C(=O)N2CCCC2)n1 +CS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1 +CCOc1ccc(C2=CCN(C(=O)C(CC)OCC)CC2)cc1 +Cc1ccc(OCc2nnc3c(C)cc(N)cn23)cc1 +COc1cccc(CC(=O)N2CCCC2c2cnn(C)c2)c1 +CC(C)Oc1ncc(C(=O)NCC2CC2C)cc1Cl +COc1ccc(Cl)cc1C(=O)NCCNc1ncccn1 +CCC(C(=O)Nc1nnc(C)s1)N1CCN(c2ccccc2)CC1 +Nc1cc2c(cc1NC(=O)c1ccncc1)CCCC2 +COC(=O)c1cccc(CNC(=O)c2cn(C)nc2C(C)(C)C)c1 +Cc1nn(C)c(-c2nc(-c3ccco3)nn2C(C)(C)C)c1Cl +CCCCS(=O)(=O)N(C)Cc1c(C)nc2sc(C)cn12 +O=C1CCC2(CCN1)CCN(c1cnc3ccc(Cl)cc3n1)CC2 +CC(=O)N1CCC(C(=O)Nc2cc(C)nn2C)CC1 +O=C(Cc1cccs1)Nc1ccc(CC(=O)N2CCCC2)cc1 +CCOCC1CCCN(C(=O)NCCc2nnc3n2CCCCC3)C1 +CNC(=O)c1ccc(NC(=O)c2oc3ccccc3c2COC)cc1 +CCn1nnc2c1C(C(=O)OC)CN(C(=O)OC(C)(C)C)C2 +CCc1nc(C)c(C(=O)Oc2ccc(N3CCCC3=O)cc2)s1 +Cn1nc(C(=O)Nc2cc[nH]n2)c2ccccc2c1=O +COC(=O)Cn1nc(C#N)cc1-c1ccccc1OC +O=C(Cc1ccc(-n2cnnn2)cc1)N(CC1CC1)C1CCCCC1 +COc1ccc2c(c1OC)C(=O)OC2Nc1ccc(O)cc1 +CSc1ccc(OC(=O)Cc2csc(C)n2)cc1 +O=C(CO)N1CCN(C(=O)C2CC2c2ccc(Cl)cc2)CC1 +Cc1noc2nc(C(C)C)cc(C(=O)NC3CCCC3)c12 +O=C(c1cc2scnc2[nH]1)N1CCCN(C(=O)C2CCC2)CC1 +CN(c1ccccn1)S(=O)(=O)c1cccc(Cl)c1 +CCNC(=O)C(C)NC(=O)NCCC(=O)N1CCCC1 +CCOc1ccc(N(C(CC)C(N)=O)S(C)(=O)=O)cc1 +CC(C)CC1COCCN1CCn1c(=O)oc2ccccc21 +CC(C)C(=O)Nc1cccc(NCC(=O)Nc2ccccc2)c1 +C=CCNC(=O)NCC1CCN(C(=O)c2cccnc2)CC1 +Cc1cc(O)c2cc(C(=O)Nc3nncs3)ccc2n1 +CCOCCOC(C)C(=O)N1Cc2ccccc2N(C)CC1CC +CCOC(=O)CCN1C(=O)C(C)Nc2cc(Cl)ccc21 +CCn1c(=O)c(C(=O)NCc2ccc(OC)cc2)nc2cccnc21 +N#Cc1ccc(COC(=O)C2CCCN2C(=O)c2cccs2)cc1 +Cc1ccn(CCC(=O)Nc2cnn(Cc3ccccc3)c2)n1 +Cc1c(NS(=O)(=O)c2ccc3c(c2)CCC3)cccc1C(N)=O +CCCCS(=O)(=O)Nc1cnn(Cc2ccc(F)cc2)c1 +COC(=O)c1ccc(C(=O)N(CC(F)(F)F)C2CCOCC2)cc1 +COCC(=O)Nc1cccc(NC(=O)NCCc2ccncc2)c1 +CNC(=O)c1ccc(OC)c(NCC(=O)N2C(C)CCCC2C)c1 +COC(=O)Cn1cc(CCn2cnc3sc(C)cc3c2=O)nn1 +CC(=O)NCCNC(=O)N(C)C1Cc2ccccc2C1 +O=C(c1csc(-c2ccco2)n1)N1CCCCCC1 +O=C(Nc1ccc(-n2cnc3ccccc32)nc1)c1cc(Cl)c[nH]1 +CC(C)(C)c1ncc(NC(=O)N2CCc3cc(F)ccc3C2)cn1 +COc1ccc(C(=O)N2CCN(C(=O)C3CC3)CC2)c(O)c1 +COCC(C)NC(=O)CN(C)c1nc2c(C)ccc(C)c2s1 +CC(Cc1ccco1)NC(=O)Nc1cnn(CC(N)=O)c1 +COCC(NC(=O)N(C)Cc1cc(Cl)cn1C)c1ccc(C)o1 +CC(C(=O)NC1(C#N)CCCCC1)N1CCN(c2nccs2)CC1 +Cc1n[nH]c(SCC(=O)N2CCCC2c2ccccn2)n1 +O=C(Cc1ccc(F)cc1)N(Cc1cnc2ccccn12)C1CC1 +CCCCC1C=CCN1C(=O)Cc1n[nH]c(=O)[nH]1 +CCCCCNC(=O)c1cccnc1-n1cncn1 +CCC1CCCCN1C(=O)c1ccc(-n2ccnc2)nc1 +Cc1cc(SCCC(=O)Nc2ccccc2)ncn1 +CC(=O)N1CCN(C(=O)CN(C)c2ccc(F)c(F)c2)CC1 +COc1ccc(CNc2cnn(CC(F)F)c2)cc1SC +COCc1ccc(CNC(=O)NCC(F)(F)F)cc1 +CC(C)OCCn1cc(C#N)c(=O)c2cc(Br)ccc21 +COCC(=O)N1CCC(c2nnc(-c3ccco3)o2)CC1 +Cc1nnc(CN(C(=O)c2sc(C)nc2C)C(C)(C)C)o1 +CCOc1ccc(-n2c(SCC(N)=O)nnc2-c2ccco2)cc1 +C#CCN1CCN(CC(=O)N2C(C)CCCC2C)CC1 +CSc1ccc(Cl)cc1NC(=O)N1CC(C)OC(C)C1 +COc1cc(C#N)ccc1OC(C)c1nc2ccccc2c(=O)[nH]1 +Cc1ccc2ncc(C(=O)Oc3cccc(Oc4ncccn4)c3)n2c1 +COc1cc(C(=O)N2CCCC2)ccc1OCc1ccc(Cl)cc1 +O=C(NCC(=O)N1CCCCC1)c1cccc2ccoc12 +O=C(CSc1nnc(-c2ccco2)n1C1CCCCC1)NC1CC1 +CCN(Cc1ccccc1)C(=O)c1nnn(Cc2ccccc2)c1C +Cc1cccc(N2CCN(C(=O)C3CC3)C(C)C2=O)c1 +Cc1cccc(C(=O)N(C)CC(=O)Nc2c(C)cccc2C)c1 +CCOc1ccc(OCC(=O)Nc2ccc(N(C)C)nc2)cc1 +CCOCCNC(=O)CN1CCOCC1C1CC1 +COc1cccc(NC(=O)Cc2ccc(OC)c(C)c2)c1 +COCCN1CCCC2(CCN(Cc3nncn3C)C2)C1=O +CN(Cc1nc2ccccc2[nH]1)C(=O)NCC(F)(F)F +COc1ccc(CN(C)c2nccc(-c3cn(C)nc3C)n2)cc1 +COc1ccc(NC(=O)CCS(=O)(=O)c2ccc(C)cc2C)cc1 +N#CCC1NCCc2cc(C(F)(F)F)c(Cl)cc21 +COc1cccc(C(=O)Nc2ccnn2Cc2cccs2)c1 +COC(=O)CCC(=O)N1CCCC1C(=O)NCc1ccco1 +O=C(CNC(=O)C1CCCC1)Nc1ccccc1N1CCCC1=O +COc1cccc(C(=O)Nc2nc(C)c(C(C)=O)s2)c1OC +O=C(Nc1cnn(-c2ccccc2F)c1)c1ccc2nncn2c1 +CCC(=O)C(C#N)C(c1ccco1)c1ccccc1OC +CCCN(C)C(=O)NCCCc1c(C)noc1C +COC(=O)N1CCCC(C(=O)N2CC(C)Sc3ccccc32)C1 +Cc1noc(CCC(=O)NC(C)(C)c2ccc(F)cc2Cl)n1 +CCc1ccc(-n2nc(C(F)(F)F)cc2N)cc1 +COCc1ccccc1C(=O)NCC(C)(O)c1ccsc1 +Cc1ccc(CC(=O)N2CCN(C(=O)c3ccccc3O)CC2)cn1 +Cc1[nH]ncc1-c1cn(Cc2ccccc2)cc1N +CCN(C(C)c1cc2ccccc2o1)S(=O)(=O)N(C)C(C)C +Cc1ccc(Cc2nc(-c3ccc(=O)[nH]c3)no2)cc1 +COc1ccc2c(=O)cc(C(=O)Nc3ccc4c(c3)OCO4)oc2c1 +COc1ccc2ccccc2c1CNc1ncn[nH]1 +CSc1c(C#N)c(-c2ccco2)nn1-c1cnc2ccccc2n1 +CCn1cnnc1CNC(=O)c1c[nH]nc1-c1ccc(F)cc1 +COC(=O)CCN1CCN(C(=O)c2sccc2C)C(C)C1 +CN(C)C(=O)CN(C)C(=O)c1cnn2c(-c3ccccc3)ccnc12 +Cc1cccc(NC(=O)COc2cccc(C(C)C)c2)c1C(N)=O +Cc1[nH]c2ccccc2c1C(=O)N1CCN(CC(N)=O)CC1 +O=C(CNC(=O)c1cccs1)Nn1cnc2ccccc21 +COC(=O)C1CC(O)CCN1C(=O)Cc1ccccc1 +COc1ccc(C(=O)NCC(=O)Nc2nc3ccccc3s2)cc1 +Cc1sc2ncn(CC(=O)N3CCC(C(N)=O)C3)c(=O)c2c1C +Cc1nc2ccccc2n1S(=O)(=O)N1CCC(C)CC1 +O=C(NC1CC1)c1ccc(NC(=O)c2ccc[nH]c2=O)cc1Cl +CCc1nn(C)c(OC)c1CNC(=O)c1cccc2cn[nH]c12 +Nc1cccc(COc2cccc(Br)c2)c1 +COc1ccccc1CC1CCCN1S(=O)(=O)c1ccccc1 +Cc1nc(COc2nc(C(C)(C)C)no2)cs1 +CCc1cccc(CC)c1NC(=O)c1ccsc1 +O=C(NCc1nnc2n1CCCCC2)N1CCCC1c1cccs1 +Cc1cc(OCc2ccc3c(c2)OCO3)nc(-c2ccncc2)n1 +CCc1noc(CC)c1CNC(=O)NCc1ccccc1Cl +Cc1nc2cc(C3CCCN3C(=O)c3cnccn3)nn2c(O)c1C +O=C(Cn1c(=O)cnc2ccccc21)Nc1ccc2c(c1)CC(=O)N2 +Cc1ccc(CN(C)C(=O)CNC(C)c2ccccc2Cl)o1 +CNC(=O)c1ccc(CSc2nnc(C)s2)cc1 +CCOc1ccc(NS(=O)(=O)c2cc(C#N)ccc2C)cc1CO +CCC(C)NC(=O)c1ccc(NC(=O)N2CCN(C(C)=O)CC2)cc1 +CCN(C(=O)c1cc(C(N)=O)cs1)C(C)c1cccc(OC)c1 +COc1cc(C#N)ccc1OCC(=O)N1CCCC1c1cc(C)no1 +COc1ccccc1NC(=O)c1ccc(S(=O)(=O)NC2CC2)cc1 +COc1ccc(-c2cc(C(=O)Nc3n[nH]c(CC(C)C)n3)n[nH]2)cc1 +CCC1c2ccccc2CCN1C(=O)c1ccnc(C(=O)OC)c1 +Cc1cc(C)cc(NC(=O)COC(=O)c2cnc(C)cn2)c1 +O=C(Nc1cccnc1)C1CCN(c2cc(-n3ccnc3)ncn2)CC1 +Cc1nnc(NC(=O)c2ccc(-n3ccnc3)cc2)s1 +Cc1ccccc1NC(=O)C(C)Sc1nnc2ccc(N)cn12 +CC(=O)c1c(C)[nH]c(C(=O)N(C)C(C)c2cccs2)c1C +Cn1cc(C(N)=O)cc1C(=O)OCC1CC1(Cl)Cl +COc1ccc(F)cc1NC(=O)N1CCC(Oc2cccnc2)C1 +Cc1cc(N2CCC(C(=O)N3CCOCC3)CC2)n2ncnc2n1 +Nc1ccc2c(c1)C(=O)N(c1ccc(F)c(F)c1)C2 +CC(C)(C)NC(=O)c1ccc(NC(=O)N2CCOC(C(N)=O)C2)cc1 +CC(C(=O)NCc1cnn(C)c1)N1CCN(c2ccc(F)cc2)CC1 +CCN(CC)C(=O)COc1ccc2ccccc2c1 +c1ccc(-c2cc(Nc3ncccn3)nc(-c3cccnc3)n2)nc1 +COCc1ccc(CNc2ccc(C(F)(F)F)nc2)o1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)c1c[nH]c(=O)[nH]c1=O +COc1cccnc1NC(=O)c1nc(-c2cccs2)oc1C +C#Cc1cccc(NC(=O)CCSc2ccccc2)c1 +CCCNC(=O)c1cc(S(=O)(=O)NC2CC2)ccc1C +Cc1ccc(C(=O)N2CCOCC2C2CC2)c(C)c1 +COc1ccc(NC(=O)NCCS(N)(=O)=O)cc1 +CCOc1ccc(-n2nnnc2CNC(=O)c2ccco2)cc1 +Cc1cccc(C(C)CNC(=O)CN(C)S(C)(=O)=O)c1 +Cc1cccnc1NC(=O)C1CCCN(c2cnc3ccccc3n2)C1 +Cc1cc(-c2cnc(N(C)C)nc2CN(C)C(=O)C2CCOC2)on1 +COCc1nc(Cc2ccc(OC)cc2)sc1C(C)(C)O +Cc1ccc(SCc2nc(N)nc(N(C)C)n2)cc1C +CN(C)C(=O)c1ccc(NC(=O)COn2nnc3ccccc32)cc1 +NC(=O)Cc1csc(Cc2ccc(F)cc2)n1 +COC(=O)C(NC(=O)c1c(C)oc(C)c1C)C(C)C +Cc1ccc(NC(=O)c2nc3ccc(O)cc3s2)cc1C +Cc1nn(C)c2ncc(C(=O)c3cc(F)ccc3O)cc12 +CNC(=O)NCC(=O)NC(C)c1nc(-c2cccc(F)c2)no1 +Cc1cc(S(=O)(=O)Nc2ccc(F)cc2OCCO)ccc1F +COc1cc(-c2noc(CC(NC(C)=O)c3ccccc3)n2)ccn1 +COC(=O)CCC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +CCC(C(=O)Nc1cccc(C(=O)NC(C)(C)C)c1C)n1cccn1 +CC1CCCC(C)N1C(=O)N1CCC(NC(=O)c2ccccc2)CC1 +CCn1nnnc1COc1cccc(C(=O)Nc2ccccn2)c1 +NC(=O)c1cccc(S(=O)(=O)NCCc2cccs2)c1 +CCOC(=O)C1CCN(C(=O)c2cc(F)ccc2N)CC1 +CCOC(=O)N(C)CC(=O)NCc1ccc(SC)cc1 +Cc1ccccc1C(=O)N1CCn2cccc2C1C +CC(=O)Nc1ccc(Cc2ccc3[nH]c(C)cc(=O)c3c2)cc1 +COc1ccc(OCC(O)Cn2c(C(C)O)nc3ccccc32)cc1 +Cn1cc(CN2CCCC(c3nncn3C)C2)c(-c2cccnc2)n1 +CCOC(=O)c1c(C)[nH]c(C(=O)NC2CCCC(C)C2)c1C +COCCOc1ccc(NC(=O)NCc2ncoc2C)cc1F +CCC(NC(=O)c1cn(C)nc1-c1cccs1)c1nc(C)cs1 +O=C(COc1cccc2c1CCC2O)NCC1CC1 +O=C(NCc1cccc(F)c1)NC1CCN(c2ccccc2)CC1 +CCOC(=O)C1CCC(NC(=O)NCC(C)(C)c2ccncc2)C1 +O=C(NC1CC1)c1cn(Cc2ccccc2)c2ccccc12 +CC(C)c1ccccc1OCC(=O)Nc1cn[nH]c1 +CNC(=O)C1CN(CCOc2ccc(C)cc2)c2ccccc2O1 +Cc1cc(NCc2ccccc2C#N)ccc1-n1cnnn1 +CCn1c(SCC(=O)c2cc(F)ccc2F)nnc1C1CC1 +Cc1cc(C(=O)NC(C)(C)C)ccc1NS(C)(=O)=O +O=C(NC1CC1)c1cccc(-c2cccc(=O)[nH]2)c1 +CC(C)C(NC(=O)C(C)n1c(=O)oc2ccccc21)c1ccccc1 +Cc1ccc(-c2ccc(=O)n(C(C)C(=O)N3CCN(C)CC3)n2)cc1 +COCCCOC(=O)C1CCCN(C(=O)c2cc(C)cc(C)c2)C1 +O=C1OCCN1Cc1cccc(C(F)(F)F)c1F +CC(Cn1cccn1)NC(=O)c1cccnc1OCC(F)(F)F +Cc1cnc(NC(=O)C2CCN(c3nc4ccccc4o3)CC2)s1 +COC(=O)C1CCN(c2ncc(C(N)=O)cc2Cl)CC1 +Cc1nsc(N2CCCN(C(=O)CSc3ccccc3)CC2)n1 +CCC(C)Oc1ccccc1-c1cc(N)c(=O)n(CC)n1 +CCCC(=O)Nc1nnc(-c2ccc(OCC)cc2)o1 +Cc1nn(C)c(N2CCC(CC(N)=O)CC2)c1CO +CCC(C(=O)Nc1cccc(O)c1)n1c(C)cc(C)nc1=O +CCCn1c(=O)c2sccc2n(CC(=O)NCc2ccco2)c1=O +CC(O)CNC(=O)C1(c2ccc(Cl)cc2)CCOCC1 +Nc1ccc(Sc2nnnn2-c2ccccc2)cn1 +Cc1cn2c(N)c(-c3ccc4c(c3)OCCO4)nc2s1 +CC(C)(C)NC(=O)CSc1ccc(Br)cc1N +CCN(Cc1ccccc1NC(=O)c1ccc(OC)nn1)C(C)=O +CSc1ccccc1NC(=O)c1cc(F)cc(F)c1 +CC(C)(C)c1ccc2c(c1)CCN2C(=O)c1[nH]c(=O)[nH]c(=O)c1N +CC1CCC(N2CCN(C(=O)Cc3ccccc3)CC2)CC1 +COc1ccccc1Sc1ccc(N)cc1C(N)=O +CC(=O)NC(CC(=O)Nc1c(F)cccc1F)c1ccccc1 +O=C(NCc1nncn1-c1ccccc1)Nc1ccc(Cl)cc1F +CCOC(=O)CN(CC)C(=O)c1cc2c(F)cccc2s1 +CC(NC(=O)CCn1cnc2c(cnn2C)c1=O)c1ccccc1F +Nc1cc(C(O)CNc2cccc(Cl)c2)ccc1Cl +COC(=O)Cc1cc(=O)oc2c(OC)c(OC)ccc12 +Cc1n[nH]c(-c2cccc(CNC(=O)c3ccccc3F)c2)n1 +C=CCN1C(=O)C(O)(CC(=O)c2ccco2)c2ccccc21 +Cc1cnc(C(=O)OC(C)C(=O)Nc2ccnn2C(C)C)cn1 +CC(C)n1cnc(-c2nc(C(=O)N3CCCC3)c3ccccn23)c1 +Cc1nn(Cc2ccccc2)c(C)c1CNc1nccnc1N +CC(OC(=O)CC(c1ccccc1)c1ccccc1)C(N)=O +Cn1nnc2c(N3CC(C(=O)Nc4ccccc4F)C3)ncnc21 +CCC(CC)c1cc(C(=O)N2CCN(CC(N)=O)CC2)on1 +Cc1ccc(CNC(=O)N2CCC3(CCC(=O)N(C)C3)CC2)cc1 +CC(=O)NC(C)C(=O)Nc1cc(C)ccc1NC(=O)c1ccccc1 +CCN(CC)C(=O)COCc1cc(-c2ccc(F)cc2)on1 +COc1ccc(F)cc1NC(=O)c1cccc(Nc2cnn(C)c2)c1 +COC(=O)C1(N(C)C(=O)c2ccccc2)CCCCC1 +COC(=O)CSc1ncn(-c2cc(C)nc(N)n2)n1 +CCOCC(=O)NC(C)c1ccc(OC)c(F)c1 +CC(C)COC(=O)C1CC(=O)N(Cc2ccco2)C1 +CCS(=O)(=O)N1CCC(C(=O)NCc2cn[nH]c2)CC1 +CC(C)(C)N1CC(C(=O)Nc2cccc(Cl)c2Cl)CC1=O +O=C(Cn1nc(-c2ccoc2)oc1=O)N1CCc2ccccc21 +Cn1c(SCC(=O)NC(c2ccccc2)C2CC2)n[nH]c1=O +COC(=O)C1CC(O)CN1Cc1cccc(OC2CCCC2)c1 +COCc1cc(C(=O)NCc2nc3ccccc3s2)ccc1F +Cn1c(SCC(=O)N(Cc2ccccc2)C(C)(C)C)n[nH]c1=O +CC(=O)c1ccc(OC(=O)Cn2c(C)c(C)sc2=O)cc1 +N#Cc1cccc(S(=O)(=O)Nc2ccc(F)cc2OCC2CC2)c1 +Cc1nc(CNC(=O)C(C)Oc2ccc(F)cc2Cl)c(C)s1 +CC(C)Oc1ccc(-c2noc(-c3ccc[nH]3)n2)cc1 +O=C(NCCCC(=O)N1CCc2sccc2C1)NC1CCCCC1 +O=C(COC(=O)C1COc2ccc(Cl)cc2C1)c1ccc[nH]1 +Cc1ccc2ccccc2c1NC(=O)c1cc[nH]n1 +Cc1ccc(CC(=O)N2CCN(CC(O)C(C)(C)C)CC2)cn1 +CC(C)CCNC(=O)c1noc2c1COc1ccccc1-2 +CC(=O)N1CC2CCC(C1)C2C(=O)NCc1ccco1 +Cc1nc(C)c(C(=O)N2CCC(Nc3cccnc3)CC2)s1 +Cc1[nH]ncc1CCCNC(=O)Nc1ccccc1 +Cc1cc(C)n(C2CN(Cc3cc(=O)n4cc(Cl)ccc4n3)C2)n1 +CN(Cc1cccc(C(F)(F)F)c1)S(=O)(=O)c1cccnc1 +CN(CCC(F)(F)F)C(=O)c1ccc2c(c1)OCCO2 +Cc1c(C(=O)OCc2nc(N)nc(N)n2)oc2ccccc12 +N#CC1(NC(=O)c2cnn(Cc3ccccc3)c2)CCCCC1 +Cc1cccc(C(=O)N2CCCC2)c1NC(=O)NCC(C)CC(C)O +CCc1nnc(CN2CCOc3ccc(F)cc32)o1 +Cc1nc(SCC(=O)N2CCCC(C(N)=O)C2)c2ccccc2n1 +CCN(C(=O)Cn1ncc(Cl)c(Cl)c1=O)C1CC1 +CN(C)C(=O)CNC(=O)c1ccc(Br)cc1 +COc1cc(C)c(C(=O)NCCCn2nc(C)cc2C)cc1OC +Cc1noc(C23COCC2CN(C(=O)c2ccnn2C)C3)n1 +COc1cc(C(=O)N(Cc2ccccc2F)C2CC2)cc(OC)c1C +Cc1ccccc1CCC(=O)NC1CCC(O)CC1 +O=C(CCn1cnnn1)N1CCN(CCOc2ccccc2)CC1 +COc1ccc(N(C)C(=O)c2cnn(CC(C)C)c2C2CC2)cn1 +CC(C)(C(=O)N1CCN(C(=O)c2csnn2)CC1)c1ccccc1 +O=C(Nc1nnc(-c2ccccn2)s1)c1cccc2c1OCCO2 +Cc1c(C(=O)NCCNC(=O)C(C)C)nc2c(Cl)cccn12 +COCCOC1C(O)C(CO)OC1n1cc(C)c(N)nc1=O +COc1cccc(CCC(=O)OCc2ccoc2C)c1 +Cc1ccccc1-c1nnn(Cc2ccccc2)n1 +Cc1cc(NC(=O)C2CC(=O)N(Cc3ccccc3)C2)n(C)n1 +COCc1c(CO)nnn1-c1cccc(C(F)(F)F)c1 +CCc1cc(-c2nnc(SCC(=O)OC)n2C(C)C)cs1 +NC(=O)N1CCCC(C(=O)NCCc2ccccn2)C1 +CCCCN(C)C(=O)CCC(=O)c1ccc(N)cc1 +O=C(c1ccsc1)N1CCc2nc(-c3ccccc3)oc2C1 +Cc1ccc(NC(C)C(=O)Nc2ccnn2C(C)C)cc1 +Cc1cc(C(=O)Nc2ccc3ccn(C)c3c2)c(C)o1 +CC(NS(C)(=O)=O)C(=O)NC(C)(C)Cc1ccccc1Cl +COCCn1c(C(=O)N=c2[nH]cc[nH]2)cc2ccccc21 +Cn1nc(CC(C)(C)C)cc1NC(=O)CNC(=O)OC(C)(C)C +Cc1ncc(CNC(=O)NCCc2cccc(F)c2)s1 +CC(C)CCNS(=O)(=O)c1ccc(F)cc1F +NS(=O)(=O)c1ccc(C(=O)Nc2ccc(F)c(Cl)c2)cc1 +Cn1c(CO)cnc1SCC1CCN(C(=O)C(C)(C)C)CC1 +CN(C)S(=O)(=O)c1cccc(NC(=O)c2cccs2)c1 +C1CN(CC2COC(CN3CCOCC3)CO2)CCO1 +COc1ccc(C(NC(=O)Cc2c(C)nc(C)[nH]c2=O)C(C)C)cc1 +CC(C)N(Cc1cnn(C)c1)C(=O)C1CC(=O)N(c2ccccc2)C1 +Cc1ccc(C)c(NC(=O)C(C)S(=O)(=O)c2nccn2C)c1 +COC(=O)c1cc(C)ccc1NCc1cc(C)on1 +CC(C)(C)n1nc(-c2ccccc2)c(C(N)=O)c1N +CCCCc1cc(NC(=O)c2cnc(CC)s2)[nH]n1 +CC(=O)N1CCCC(C(=O)NCCS(=O)(=O)c2ccccc2)C1 +CC(=O)c1cc(C#N)c(SCC(=O)N2C(C)CCCC2C)nc1C +COc1cc(NCc2nnc(C(C)(C)C)o2)c(OC)cc1Cl +CN(CCc1ccncc1)c1ncc(N)cc1Cl +Cc1ccc2[nH]nc(C(=O)NCC(O)c3ccco3)c2c1 +CC1CC1NC(=O)c1cnc(C2CCCO2)s1 +CCCc1ccc(C(C)NC(=O)c2cccnc2)cc1 +Cc1noc(C)c1CC(=O)NC(Cc1ccccc1)c1ccccc1 +Cn1ccnc1C(NC(=O)CC(C)(C)C)c1ccccc1 +Cc1ccccc1OCC(=O)Nc1ccc(C)c(N2CCCC2=O)c1 +O=C(Nc1cc(Cl)ccc1O)c1ccc2[nH]cnc2c1 +CCCCc1nnc(NC(=O)c2cccnc2OCC)s1 +Cc1ccc(C)c(C(O)CNC(=O)c2ccccc2Cl)c1 +Cc1ccc(-c2nc(-c3cccc(N)c3)no2)s1 +COCCCNC(=O)c1cn(C)nc1-c1ccc(F)cc1F +Cc1c(-n2cnnn2)c(=O)n(-c2ccccc2)n1C +O=C(NC1CC1)c1nn(-c2ccc(F)cc2)nc1CO +Cc1cccc(C(C)C)c1NC(=O)Cc1ccc[nH]1 +Cc1nccc(C2CCCCN2Cc2ccccc2)n1 +CC(C)Oc1ccc(Cl)cc1C(=O)Nc1ccncc1 +COc1ccc(F)cc1-c1csc(NCc2ccco2)n1 +C=CCNC(=O)CC1CN(Cc2ccccc2)CCO1 +O=C(NCc1cc(=O)[nH]c2ccccc12)Nc1cnn(CC(F)F)c1 +Cc1nc(-c2cccs2)ccc1C(=O)N(C)C(C)c1cccnc1 +CCOc1ccc(-n2c(=O)[nH]c3ccsc3c2=O)cc1 +Cc1cc(F)ccc1NS(=O)(=O)Cc1ccccc1 +Cc1ccc(-n2nc(C)cc2NC(=O)COCC(F)(F)F)nn1 +O=C(c1nccs1)C1CCN(C(=O)CC2CCCC2)CC1 +Cc1cccc(NC(=O)c2ccc3c(c2)NC(=O)C(C)S3)c1C +COc1cc(C(=O)N2CCC2)ccc1OC(F)F +CC(=O)Nc1ccc(O)c(C(=O)N2CCC(C)CC2)c1 +OCCCc1nc2cc(Br)ccc2[nH]1 +CC(c1ccccc1)n1cnnc1Cc1ccc(O)cc1 +Cc1c[nH]c(=NC(=O)c2ccccc2Cn2cncn2)[nH]1 +Cn1nnnc1SCC(=O)c1ccc(F)cc1 +CN(C)C(=O)CN(c1ccc(C(F)(F)F)cc1)S(C)(=O)=O +O=C(CCN1CCOC1=O)Nc1nc(C(F)(F)F)cs1 +O=C1Nc2ccc(Br)cc2C1(O)C(F)(F)F +Oc1ccc(CNc2c[nH]nc2-c2ccccn2)cc1 +CC(=O)Oc1cc2occ(-c3cscn3)c(=O)c2cc1C +CC(=O)c1sc(C(C)N2CCc3ccccc3C2)nc1C +Cc1cc(NC(=O)NC(C)CCC(C)C)ccc1C(=O)N(C)C +CSc1cc(C(=O)Nc2ccccc2N2CCCCC2)ccn1 +COc1ccc(C(CC(N)=O)C2CCCC2)cc1OC +Cc1ccn2c(=NC(=O)C3CC3c3ccc(C)s3)[nH]nc2c1 +CC(C)C(=O)N1CCN(C(=O)Cn2cnc3ccccc3c2=O)CC1 +COc1ccc(-c2n[nH]cc2C(=O)Nc2ccc3c(ccn3C)c2)cc1 +O=C(c1ccco1)N1CCC(Oc2cnc3ccccc3n2)CC1 +Cc1noc(COCC(=O)NC2CC3CCC2(C)C3(C)C)n1 +Cc1cc(C2CCCN2C(=O)c2ccc(OCC(N)=O)cc2)no1 +O=C(NCC#CCOc1cccc(Br)c1)c1cnccn1 +CC1CN(C(=O)c2[nH]c3ccccc3c2Br)CCO1 +Cc1cccc(C(=O)OCC(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +N#Cc1ccc(SCC2=NS(=O)(=O)c3ccccc3N2)cc1 +Nc1ccc(SCC(=O)Nc2ccc(F)cc2)cc1 +O=C(CSc1ccccn1)c1ccc2c(c1)OCO2 +O=C(CCn1cncn1)N1CCCC1c1ccncc1 +CC(C)n1cnnc1S(=O)(=O)CCCc1nc2ccccc2o1 +O=C(CCn1cncn1)Nc1ccc(Oc2cccnc2)nc1 +CC(=O)c1sc(NS(=O)(=O)c2cc(C)ccc2C)nc1C +CCC1CCCCN1C(=O)C1CC(=O)N(c2ccc(OC)cc2)C1 +Cc1cccc(CCC(=O)Nc2ccc(CN3CCOC3=O)cc2)c1 +CNC(=O)c1c(-c2ccc(Cl)cc2)cn2c(C)cc(C)nc12 +O=C(C1CCCN(c2cnccn2)C1)N1CCCC(c2ccn[nH]2)C1 +CN(C)C(=O)c1ccc(C(=O)N(C)Cc2cccc(C#N)c2)cc1 +Cc1cccc(NC(=O)c2cc(NC(=O)c3ccco3)n(C)n2)n1 +Cc1nn(-c2cccc(Cl)c2Cl)c(C)c1N +O=C(CNC(=O)NCC1CCCC1)Nc1cccc2c1OCO2 +CS(=O)(=O)c1nc(C(=O)NCC2CCCCO2)c2ccccn12 +Cc1ccccc1-c1nnn(CC(=O)N2CCC2)n1 +COC(=O)C1CN(CC=Cc2ccccc2)CC(C)O1 +NC(=O)c1n[nH]c2ccc(NC(=O)CCNC(=O)c3ccco3)cc12 +Cc1cccc(NC(=O)c2ccc(Cn3cccn3)o2)c1 +CC(c1cc2ccccc2o1)N(C)C(=O)c1ccc(=O)[nH]c1 +CCSc1nnc(SC(C)C(=O)NC2CC2)s1 +CNS(=O)(=O)c1ccc(NC(C)COC)c(N)c1 +COc1nc2ccn(Cc3csc(C)n3)c(=O)c2cc1C#N +CN(Cc1ccc(SC(F)F)cc1)S(=O)(=O)CC1(C#N)CC1 +Cc1n[nH]c(SCc2nc(Cc3ccccc3)no2)n1 +CCOC(=O)CSc1nc(C)cc(Oc2ccc(=O)n(C)n2)n1 +Cc1cc(C(O)CCC(=O)NC(C)(C)C)ccc1F +C#CCNC(=O)COc1ccc(Oc2ccccn2)cc1 +CCCc1ncc(C(=O)N(C)c2ccccc2S(C)(=O)=O)s1 +C=CCOC1CC2CC1N(C(=O)c1sccc1C)C2 +O=C(CSc1nnc(-c2cccnc2)o1)NCCc1ccccc1 +CNC(=O)CN(Cc1ccccc1)S(=O)(=O)c1ccc(C)cc1 +c1nc(NCCC2CC3CCC2C3)c2nc[nH]c2n1 +CN(Cc1cnn(C)c1)C(=O)C1CCCN1C(=O)c1ccccc1O +CCn1c(=O)c2ccccc2n2c(COc3cccc(F)c3)nnc12 +C=CCNC(=O)c1ccccc1NC(=O)c1cnc2ccccc2n1 +COc1cc(C)ccc1OC(=O)c1cc(C(N)=O)cn1C +Cc1cccn(C(C(=O)Nc2ccccc2N)C(C)C)c1=O +Cc1ccc(F)cc1C(=O)N(C)Cc1ccc(F)cc1 +CCOc1ccc(N(CC)C(=O)Cn2c(=O)oc3ccccc32)cc1 +Cc1c(C)n(CCO)c2ncnc(NCC(C)C)c12 +O=C(Nc1cccc(F)c1)c1ccc2c(c1)[nH]c(=O)c1ccncc12 +O=C(Nc1nccs1)N1CCN(CC(F)F)CC1 +Cc1cc(NCc2cncc(Br)c2)no1 +Cc1c(Br)cc2c(CCO)noc2c1C +CC(=O)NCc1nnn2c1CN(c1ncccn1)CCC2 +COc1cc(OC)cc(-c2nnc(NC(=O)C(C)(C)C)o2)c1 +Cc1ccc(NC(=O)c2ccc(-c3noc(C(F)(F)F)n3)cc2)nc1 +CC(C)N(CC1CC1)C(=O)c1cc(Br)cn1C +Cc1ccc(CN(C)C(=O)c2cccc3ccccc23)o1 +O=C1CSc2ccc(C(=O)Nc3ccc(Cl)c(F)c3)cc2N1 +COC(=O)c1ccc(C(=O)Nc2cccc(Cl)c2C)cn1 +CC(C)OC(=O)Cn1c(=O)oc(=O)c2ccccc21 +O=C(NCc1nc(C2CC2)no1)N1CCOC(c2ccccc2)C1 +O=c1sc2ccccc2n1Cc1nnnn1C1CC1 +CCCN1C(=O)Cc2cc(C(=O)NCc3ccccc3OC)ccc21 +Nc1ccc(C(=O)NCC(=O)Nc2cccnc2)cc1 +Cc1ccc(NC(=O)COc2ccc(C(N)=O)cc2)cc1C +CC(C)CN1CCN(S(=O)(=O)Cc2cccc(C#N)c2)CC1 +Cc1noc(COCC(=O)N(C)c2cccc3ccccc23)n1 +O=C(C=c1[nH]c(=O)c(=Cc2ccc(Cl)cc2)s1)c1ccco1 +Cc1ccc(NC(=O)CSc2nc3c(N)ncnc3[nH]2)cc1 +N#Cc1cccc(C(=O)NCc2cccnc2OCC(F)(F)F)c1 +COCC1CCCN(S(=O)(=O)N2CCCC2c2ccco2)C1 +COc1nn(C)cc1C(=O)N1CCC(Oc2ccc(C)nc2)CC1 +Cc1ccc(CNC(=O)CCc2cccc(Cl)c2Cl)cn1 +COCCCC(=O)Nc1cccc(NC(=O)c2ccccc2)c1 +CCCc1nc2cc(Br)cnc2n1CCO +CCOc1ccccc1NC(=O)CSc1nc2c(c(=O)[nH]1)CCC2 +CC1(NC(=O)CCc2nc3ncccc3[nH]2)Cc2ccccc2C1 +CCCCc1nc2c(OCCO)cccc2s1 +COCCOc1c(Cl)cccc1NC(=O)CC1C=CCC1 +CNC(=O)CN(C)S(=O)(=O)c1ccc(C(N)=O)cc1 +O=C(Cc1cn2ccsc2n1)NC1CCc2c(F)cccc21 +Cn1ccc(NC(=O)C(C)(C)Oc2ccc(F)cc2)n1 +CC(=O)Nc1cccc(NC(=O)Nc2cc(Cl)ccc2F)c1 +O=C(CCNC(=O)c1cc2cnsc2s1)NCc1ccncc1 +O=C(Nc1ccc(Cl)c(Cl)c1)c1ccc(-n2cncn2)nc1 +CC(Cn1cccn1)NC(=O)Cc1cc(Cl)c2c(c1)OCCCO2 +COc1ccc(OCCc2nc(C)c(C(C)(C)O)s2)cc1 +COC(=O)c1cc(F)c(C)c(NC(=O)c2sc3nccn3c2C)c1 +CCN(Cc1cccc2c1OCCO2)S(=O)(=O)N(C)C +Cc1cc(C(N)=O)c(NC(=O)C#Cc2ccccc2)s1 +Cc1cc(-c2csc(NC(=O)c3ccc(=O)[nH]c3)n2)c(C)o1 +CCN(CC)C(=O)CN(CC)S(=O)(=O)c1ccc(Cl)cc1 +CC(=O)Nc1cc(C(=O)N2CC(C(N)=O)CCC2C)ccc1F +O=C(COc1ccccc1O)NC(c1ccccc1)c1ccncc1 +N#Cc1ccccc1CSc1nnc(N)n1-c1ccccc1 +CN(C)c1cccc(Oc2ccc(N)cc2Cl)c1 +CCNC(=O)CCC(O)c1cc(C)c(OC)cc1C +Cc1cc(C(=O)NC(C)c2ccc3c(c2)OCCO3)on1 +Cc1nc(NC(=O)c2cnn(-c3ccccc3Cl)c2C)n[nH]1 +O=C(Nc1ccccc1)N1CCC(c2nnc(-c3ccoc3)o2)CC1 +Cc1cc(C(=O)Oc2ccc3c(c2)OCCO3)nn1C(C)(C)C +Cc1n[nH]cc1NC(=O)c1sc2cccc(F)c2c1C +CC(C)Oc1ccccc1CS(=O)c1nc[nH]n1 +CCC1CCCCN1C(=O)CCn1cnc2c1c(=O)n(C)c(=O)n2C +CCN(CC)C(=O)c1cc(Cl)c(C)c(F)c1F +Cc1cc(NC(=O)NCCc2c(O)n[nH]c2C)no1 +CCN(c1ccc(C(=O)N2CCOCC2C2CC2)cc1)C(C)C +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)c(Cl)c2)c1C +Cc1c(C(N)=O)sc2nc(C)n(Cc3cccc(C#N)c3)c(=O)c12 +CN(C(=O)COC(=O)c1sccc1N)C1CC1 +CCn1c(C2CCCN(C(=O)c3cc(C(C)C)on3)C2)nn(C)c1=O +CCN(CC(=O)N(C)CC1CC1)c1ccccc1C +O=C(CCc1ccco1)OCc1nnc(-c2ccccc2Cl)o1 +CCc1ccc(NC(=O)c2cc3c(CO)cnc(C)c3oc2=O)cc1 +CCOC(=O)CSc1ncnc2sc(CC)cc12 +COC(=O)c1cc(CNC(=O)Nc2nnc(C3CC3)s2)oc1C +Cc1noc(C)c1-c1nn2c(-c3ccncc3)nnc2s1 +NC(=O)NC(CC(=O)Nc1ccc2c(c1)CC(=O)N2)c1cccs1 +CCC(C)NC(=O)C(Sc1nncs1)C(C)C +CCc1nnc(SCc2nnc(C(F)(F)F)o2)n1N +O=C(NCc1ccc(OC2CCCCC2)nc1)c1cnccn1 +C#CCN1CCN(C(=O)NCC(C)c2ccc(F)cc2F)CC1 +COc1cccc(-c2nc(CC#N)cs2)c1OC +CC(C)C(NC(=O)c1ccn2nnnc2c1)c1nc2ccccc2[nH]1 +CCCCN(C)C(=O)Nc1ccccc1C(=O)N1CCOCC1 +CC(=O)c1cnc(-c2ccncc2)n1Cc1ccccc1 +Cc1cc(C)nc(C(C#N)C(=O)CCc2c[nH]c3ccccc23)n1 +CCNc1ncc(Br)cc1C(=O)N(C)C(CC)CC +CC(=O)c1ccc(S(=O)(=O)N2CC(C)OC(C)C2)cc1 +COc1ccc(CCNC(=O)C(C)(C)NC(C)=O)cc1OC +COc1cc(CNc2nnc(C)s2)ccc1Cl +COCCN(Cc1ccncc1)Cc1cc(=O)c2cc(C)ccc2[nH]1 +c1ccc(CN(Cc2ccncc2)Cc2ccsc2)cc1 +CC(C)(O)CCc1ccc(C(=O)N2Cc3cnn(CCO)c3C2)cc1 +COc1ccccc1Cc1nccn1Cc1ccccc1C#N +Cc1cccc(S(=O)(=O)C(C)C(=O)Nc2c(C)cccc2C)c1 +CCCCCC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +COCCC1NCCc2ccc(C)c(Br)c21 +CCOC(=O)c1cc(N)n(-c2ccc(C)c(C)c2)n1 +O=C(NC1CC1)C1CCCN1C(=O)Nc1cccc(C(F)(F)F)c1 +CC(C)C1CCCN1C(=O)CN(C)c1ccc(C#N)cn1 +COc1ccccc1OCC(=O)NCC(C)(O)c1cccs1 +CC(C)N(Cc1ccccc1)C(=O)CSc1nncn1C +Cc1cc(Cl)ccc1NC(=O)C1CC(=O)N(C2CC2)C1 +C=CCN(C(=O)c1cnc(C)s1)c1nc(-c2ccccc2)cs1 +NC(=O)N1CCC2C(COC2CNC(=O)c2cscn2)C1 +CCOC(=O)C1=C(CC)NC(=O)NC1c1cccc(C)c1 +COC(=O)c1sc(NC(=O)c2cccc(OC)c2OC)nc1C +CCC(=O)Nc1ccc(NC(=O)Nc2ccc(C#N)cc2)cc1 +Cc1cc(C)cc(-n2ncc(CNc3nnc(C)o3)n2)c1 +CC1CN(C)c2ccccc2CN1C(=O)c1cnccn1 +CCC1CCCCN1C(=O)CCc1cc(N)cc(OC)c1OC +CC(C)(C)NC(=O)COC(=O)c1cccc(Br)c1 +O=C1CCC(NC(=O)c2cc3ccccc3o2)CC1 +COC(=O)C1(NC(=O)C2CC(=O)N(Cc3ccco3)C2)CCCC1 +CN(C)S(=O)(=O)CCCn1cc(-c2ccccc2)cn1 +CCC(C)Oc1ccccc1-c1cnn(C)c(=O)c1CO +CN(C)S(=O)(=O)N1CCN(C(=O)C2CCCCC2)CC1 +COc1ccc(N)c(C(=O)NC(C)C2CCCO2)c1 +CCC(C#N)Oc1cccc(CNC(=O)Nc2cnccc2C)c1 +c1cnn(-c2ccc(CNCc3cnc(N4CCCC4)nc3)cn2)c1 +CCc1nc(CC(=O)Nc2ccc(Oc3cccnc3)nc2)cs1 +O=C(c1ccc(=O)[nH]c1)N(CCc1ccccc1)Cc1ccccc1 +Cc1nc2nc(C)c(C)c(Sc3ccccc3N)n2n1 +CC(C)Cn1cc(NCc2ccc(-n3cccn3)cc2)cn1 +CCN(CC)C(=O)c1c(C)nc(N)nc1C1CCCCC1 +COc1cc(NC(=O)C(C)(C)C)c(C(=O)NC2CCCC2)cc1OC +COc1ccc2c(c1)CC(C(=O)NCCCN1CCOCC1)CO2 +Cc1sc2nc(-c3ccc(S(C)(=O)=O)cc3)[nH]c(=O)c2c1C +NC(=O)CC1CCN(C(=O)NCc2ncc(-c3ccccc3)o2)CC1 +CN(Cc1cscn1)c1cccc(Cl)c1CO +COCCNC(=O)CC(C#N)c1ccc(Br)cc1 +COCc1ccc(C(=O)NCc2ccc(C#N)cc2)o1 +CC(=O)Nc1ccc(S(=O)(=O)NCc2cccnc2)cc1 +Nc1nccnc1C(=O)N1CCCC(c2nnc3n2CCCCC3)C1 +CCc1noc(CC)c1CC(=O)Nc1c(N(C)C)ccnc1OC +CC(Cn1cnnc1)NC(=O)N1CCCC1C1CCC1 +Cc1ccc(-n2ccnc2)c(C(=O)N(C)Cc2c(C)noc2C)c1 +CCc1ccccc1NC(=O)Cn1c(=O)cnc2ccccc21 +CC1CN(Cc2nc3scc(-c4ccccc4)c3c(=O)[nH]2)CCO1 +CC1CCc2onc(C(=O)NC3CCCCC3C)c2C1 +Cc1cccc(OCC(=O)Nc2cc(N)ccc2F)c1C +CCOC(=O)N1CCC(NC(=O)c2cccc(OC)c2F)CC1 +COC(=O)Cc1c(C)c2ccc3c(c2oc1=O)CN(CC(C)C)CO3 +CS(=O)(=O)N1CCC(NC(=O)N2CCc3sccc3C2)CC1 +CC(C)CCC(=O)Nc1cc(-n2nnnc2C2CC2)ccc1F +Cc1ccc(CC(=O)Nc2ccccc2C(=O)N2CCCC2)cc1C +COc1cccc(C(=O)Nc2ccc(C(=O)NC(C)C)cc2C)c1F +Cc1cc(NC(=O)C(C)Oc2ccc(C#N)cc2)n(CCC#N)n1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2ccccc2Cl)n1 +Cc1cc(Cl)ccc1NS(=O)(=O)c1cccc(O)c1 +CC(CN(C)C(=O)Nc1ccc(C(N)=O)cc1F)c1nccs1 +COc1ccccc1NC(=O)CC(C#N)c1ccccc1 +N#Cc1ccccc1Oc1ccc2sc(=O)oc2c1 +NS(=O)(=O)CCCNC(=O)c1cc(F)ccc1F +Clc1cccc(Cc2nc(-c3ccc4nncn4c3)no2)c1 +CC1(NC(=O)c2cccc(-n3cnnn3)c2)CCCC1 +Cc1nc(-c2ccco2)ccc1C(=O)N1CCOc2ccc(F)cc21 +CCNC(=O)Cc1c2c(n(CC(C)C)c1C)CC(C)(C)CC2=O +Cc1ccnc2nc(C(=O)Oc3ccc(NC(=O)C4CC4)cc3)nn12 +Cc1ccc(S(=O)(=O)Nc2cnn(C)c2)cc1F +O=C(CCNC(=O)c1ccc2cnsc2c1)Nc1nccs1 +COc1ccc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)nn1 +NS(=O)(=O)c1ccc(F)c(C(=O)Nc2ccccc2F)c1 +COCCCNC(=O)CSc1nnc(N)n1C +Cc1noc(C)c1CC(=O)Nc1nc(-c2ccco2)cs1 +O=C(c1cccnc1)N1CCN(Cc2ccccc2Cl)CC1 +Cc1cc(-c2csc(NC(=O)c3cccc(N(C)C)c3)n2)c(C)o1 +CC(OC(=O)c1cccnc1)C(=O)NCc1ccc2c(c1)OCO2 +Cn1ccnc1Cc1nn2c(-c3ccccc3)nnc2s1 +O=C(Nc1cccnn1)N1CCOC(CCc2ccccc2)C1 +O=C(C1CCCO1)N1CCN(c2ccc(-n3ccnc3)nn2)CC1 +CCc1nnc(SCC(=O)Nc2ccccc2F)n1-n1cccc1 +CCOC(=O)c1cnc(NCCN2CCOCC2)[nH]c1=O +COC(=O)c1ccc(Nc2nc(C)nc3c2CCC3)cc1 +Cc1nnnn1-c1cccc(NCc2nc(-c3ccsc3)no2)c1 +CCC(C)N(C)C(=O)NCc1ccnc(OC)c1 +COCc1cc(=O)n(CC(=O)Nc2ccc(C)c(C)c2)c(N)n1 +O=C(C1CCC1)N1CCC(c2n[nH]c(=O)n2Cc2ccccc2)CC1 +CC(=O)N1CCCC1c1nccnc1CCC(N)=O +CC(C)N(CC(N)=O)C(=O)CCc1ncc(-c2ccc(Cl)cc2)o1 +Cc1cc(N(CCO)CCO)nc(Nc2ccccc2)n1 +O=C(Nc1cn[nH]c1)c1c[nH]nc1-c1cccc(Cl)c1 +COc1cc(C(=O)NCC2CC2)cc2c1OCCO2 +COc1ccc(CNC(=O)C2COCCO2)cc1Br +Cc1c(C(=O)NC(C)C)nnn1-c1ccc(Cl)cc1 +NC(=O)c1ccc(NC(=O)NCc2nnc3ccccn23)cc1 +CCCc1nc(C(=O)NCc2ccncc2)cs1 +C=CCNC(=O)C1CN(c2nc3ccc(OC)cc3s2)C1 +CC(C)COC(C)C(=O)Nc1ccc(F)c(F)c1F +Cc1cc(C(=O)CN2CC(C)OC(C)C2)ccc1F +O=C(CNC(=O)c1ccc(F)cc1F)NCc1ccc2c(c1)OCO2 +O=C(Nc1cnn(C2CCOCC2)c1)c1ccc(-c2ccccc2)cc1 +CN(C)S(=O)(=O)N1CCC2(CC(Oc3ncccc3F)CO2)C1 +CCOC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)c1ccc(F)cc1 +O=C(CNC(=O)c1cc(F)cc(F)c1)Nc1ccccn1 +N#Cc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1Cl +CCc1n[nH]c(C2CN(C(=O)c3cnc4[nH]nc(C)c4c3)CCO2)n1 +O=S(=O)(c1cncc(Cl)c1)N1CCC(CCO)C1 +COC(=O)N1CCCN(C(=O)Nc2ccc(C)cc2)CC1 +Clc1ccccc1NCc1noc(-c2cccs2)n1 +COc1ccc(C(=O)N2CCN(c3ccccc3)CC2)cc1OC +Cc1ccc(S(=O)(=O)NCC(=O)NCCc2ccccc2)cc1C +Cc1ccc(NC(=O)NC(C)c2cccnc2)cc1C +CC(C)Sc1nnc(COc2ccc(Cl)cc2)o1 +CC(C)(NC(=O)Nc1cccnc1)c1ccccc1 +CC(CCc1ccco1)NC(=O)c1cccnc1Oc1cccnc1 +O=C(c1cc(Cl)c[nH]1)N1CCN(Cc2ccccc2F)CC1 +COc1ccc2cc(NC(=O)CNC(=O)c3cnccn3)cnc2c1 +COc1cccc2cc(C(=O)Nc3cccc(C)c3C(N)=O)oc12 +CC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2occc2C)c1C +CC(C(=O)N(C)C)N1CCN(C(=O)COc2ccc(F)cc2)CC1 +CC(C)C1C(=O)N(C)CCN1C(=O)c1cnc(-c2ccncc2)nc1 +O=C(OCc1nc2ccccc2s1)c1ccncc1F +Cc1ccc(NC(=O)N2CC(c3nc(-c4ccccn4)no3)C2)cc1C +COc1cccc2c1CCNC2c1cccnc1F +O=C(Nc1nnc(C2CC2)s1)c1cccc(Cl)c1 +Cc1ccnc(NC(=O)c2ccc3nc4c(nc3c2)C2CCC4C2)c1 +COC(=O)C1CCCC(=O)N1c1ccccc1OC +CCOC(=O)C(C)NC(=O)CNc1ccccc1 +Nc1cc(Br)c2c(c1)CCCCS2 +CCc1nnc2n1CCN(Cc1nc(C3CC3)no1)C2 +COc1ccnc(NC(=O)Cn2c(C3CC3)nc3ccccc32)c1 +C=CC(CC(=O)Nc1nccn(C)c1=O)c1ccccc1 +NC(=O)CCNc1ncc(C(F)(F)F)cc1Cl +Cc1cc(=O)n(CC(=O)Nc2ccc(F)cc2)c(N2CCOCC2)n1 +COc1ccc(-n2nnc(CO)c2-c2ccccc2OC)cc1 +N#Cc1ccc(Cl)c(NC(=O)c2cc3ccccc3oc2=O)c1 +CCc1nc(CNc2cc(NC(C)=O)c(F)cc2F)cs1 +CC(O)C1CCN(C(=O)c2ccc3ccc(Cl)cc3n2)CC1 +Cc1ccc(Cl)cc1NCC(=O)N1CCCCC1 +O=C(c1csc2nc(-c3cccc(Cl)c3)cn12)N1CCCC1 +Cc1ccn2c(=NC(=O)c3ccc(Cn4cccn4)cc3)[nH]nc2c1 +Cc1ccc2ncc(C(=O)NCC(C(C)C)N3CCOCC3)n2c1 +CC(C)CC(=O)NC1CCCc2ccc(C(O)C(C)C)cc21 +Cc1nc(C2CC3CCN(C(=O)c4cnoc4C)CC3O2)sc1C +COc1c(F)cc(NC(=O)C2CCCN2C(=O)C(C)C)cc1F +CN(CC(F)(F)F)C(=O)Cn1c(=O)oc2cccnc21 +CCCn1ncc(-c2cccc(Cl)c2)c(CC#N)c1=O +Cc1cc(NCc2cn[nH]c2-c2cccs2)nc(-c2cccnc2)n1 +CN(C)c1ncccc1C(=O)N1CCOC(c2ccc(Cl)cc2)C1 +COc1ccc(NC(=O)c2ccon2)cc1OC(C)C +Cc1cc(Br)c2nc(-c3cccnc3)oc(=O)c2c1 +FC(F)Oc1cccc2c1CCNC2c1cnccn1 +O=C(NCC(O)c1ccc(F)c(F)c1)c1ccco1 +Cn1cnnc1S(=O)(=O)CCCc1ccccc1 +O=C(Cc1ccccc1)NCC(=O)N1CCOCC1C1CC1 +COc1ccc(C(=O)OCC(=O)NC(C)(C)C)cc1Br +C=CCN(Cc1ccccc1OCC)C(=O)C1CCC1 +O=C(Nc1cccc(OCC(F)F)n1)c1ccncc1 +Cc1cccnc1NC(=O)c1ccn(-c2cccc(C(F)(F)F)c2)n1 +CCC(NC(=O)NCC1CCCO1)c1cccc(Cl)c1 +Cc1nc(-c2cc(C(=O)N3CCOCC3CC(C)C)n(C)c2)cs1 +Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)N(C)C)CC2)c1 +CCNC(=O)c1cccc(CNC(=O)C2(c3cccc(C)c3)CC2)c1 +CCOC(=O)c1cn(-c2cccc(Cl)c2)nn1 +CCOC(=O)C1=C(N)Oc2cc(O)ccc2C1c1cccc(Cl)c1 +O=C(CC1CCCC1)NCC1CCN(C(=O)c2cccnc2)CC1 +CC(Sc1ncccn1)C(=O)Nc1cc(N)ccc1F +CC(CO)(NC(=O)NC(c1ccc(F)cc1)C1CC1)C1CC1 +Cc1cccnc1NC(=O)c1ccc(N(C)C)cc1 +CCC(=O)c1ccc2c(c1)N(Cc1ccccc1)C(=O)CO2 +Cc1ccc2nc(C(=O)N3CCCC3c3cccnc3)cn2c1 +CCc1ccccc1N1CC(C(=O)N(C)Cc2ccccc2)CC1=O +O=C1Cc2cc(NC(=O)C3(c4ccccc4)CCOCC3)ccc2N1 +CCS(=O)(=O)N1CCC(NC(=O)c2cc(F)ccc2C)CC1 +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1cc(F)cc(F)c1 +Cc1onc(-c2ccccc2)c1C(=O)N1CCOC(c2ccccc2)C1 +CCCC(C)NC(=O)C(C)S(=O)(=O)c1ccc(NC(C)=O)cc1 +Cn1nnc2c1CCN(CC1CC1)C2COCc1ccccc1 +Cc1ccc(OCn2ccc(C(=O)NCC3CCC3)n2)c(C)c1 +CCCCOc1ccc(C(=O)N2CCCCC2C(=O)NC)cc1 +COCCCn1nnnc1-c1ccc(N)c(F)c1 +Cc1cccc(C)c1NC(=O)CNc1c(F)cccc1N1CCCC1 +Cc1ccc2cnn(CCC(=O)NC(CO)Cc3ccccc3)c2c1 +CCc1ccc(CCNC(=O)c2cnn(-c3ccncc3)c2C)cc1 +N#Cc1cccnc1-n1c(N)nc2cccc(F)c21 +Cc1ccoc1C(=O)NCc1cccc(NC(N)=O)c1 +O=C(Nc1ccccc1Cl)C1CCN(C(=O)c2ccco2)CC1 +O=C(NCc1ncc(-c2ccccc2)o1)C1CC1c1ccccc1 +CCc1nnc(CN(C)C(=O)c2cc(C)nc3c(C)c(C)ccc23)o1 +CC(C)NC(=O)Nc1ccc(C(=O)N(C)CCN2CCOCC2)cc1 +C=CCn1nnnc1SCc1nnc(C2CC2)o1 +COc1ccccc1CNC(=O)c1cc2c(F)cccc2n1C +Cc1nc(CN2CCN(C(=O)c3cn4ccccc4n3)CC2)cs1 +CC(Sc1ccccn1)C(=O)NCCn1cnnc1C(C)C +CCC(O)C(=O)NCc1cccnc1Oc1c(C)cccc1C +COCc1ccccc1NC(=O)NC(C)c1nc2ccccc2[nH]1 +Cc1nc2ccccc2n(CCC(=O)Nc2cccc(F)c2)c1=O +CCCNC(=O)CCNC(=O)N1CCC(Oc2ccccc2)CC1 +COCC(C)(O)CNS(=O)(=O)c1cccc(C(C)=O)c1 +O=C(NCC(=O)N1CCc2ccccc21)c1cc2cc(=O)[nH]cc2[nH]1 +COc1ccc(OCCNc2ccc(C(N)=O)cc2)cc1 +O=C(Nc1cc(-c2ccc(F)c(F)c2)no1)c1ccccc1 +COc1cc(CC(=O)Nc2cc(C)ccc2C)cc(OC)c1OC +O=C(c1cccc(F)c1)N1CCC2(CC1)CNc1ccc(Cl)cc12 +CCn1nc(C)cc1NC(=O)CCCS(=O)(=O)c1ccccc1 +CCC(OC)C(=O)NC1(c2ccc(F)cc2)CCC1 +CS(=O)(=O)N1CCC2(CC1)CC(OCc1ccccn1)CO2 +CCc1ncc(C(=O)NC(Cc2ccccc2)C(N)=O)cn1 +CC(NCC(O)c1ccc(F)c(F)c1)c1cccs1 +O=C(Cc1ccc[nH]1)NCCc1c[nH]c2cc(F)ccc12 +CNC(=O)C1CCC(NC(=O)Nc2ccc(OC)nc2)CC1 +N#Cc1cccc(-c2cn3c(n2)N(C(=O)c2ccccc2)CCC3)c1 +O=C(COc1ccc2c(c1)OCO2)NCCCn1ncccc1=O +C=CCn1c(SCc2nnc(CC)o2)nnc1C(C)(C)C +Cc1cc2nnc(-c3ccccc3Br)n2cc1N +NC(=O)c1ccccc1COC(=O)c1cccc(-c2ccoc2)c1 +Nc1c(NCCC2=CCCCC2)ncnc1N1CCN(CCO)CC1 +CC(=O)N1CCC(NC(=O)c2ccc3c(=O)[nH]c(=O)n(C)c3n2)CC1 +CC(=O)Nc1cc(C(=O)Nc2cc(Cl)ccc2F)ccc1F +Cc1nc(-c2cccc(C(=O)NCC(O)C3CCOCC3)c2)cs1 +CCc1noc(CC)c1CNC(=O)c1sccc1SC +CSc1ccc(C(=O)Nc2ccnn2C(C)C)cc1 +O=C(NCc1noc(-c2ccco2)n1)C1CCOc2ccccc2C1 +CC1CCCN(c2cnn(-c3ccccc3)c(=O)c2Br)C1 +O=C(Nc1ccon1)c1ccc(=O)n(-c2ccccc2)c1 +C#CCNC(=O)N(C)Cc1cc(C(=O)OC)c(C)o1 +O=C(c1n[nH]c(=O)c2ccccc12)N1CCCC1C1CCCC1 +O=C(Cn1c(-c2ccccc2)noc1=O)NCc1cccs1 +CC(NC(=O)c1cccn1Cc1cccs1)C(N)=O +COc1cccc(NC(=O)c2cc(S(N)(=O)=O)c(C)o2)c1 +OCCc1nc2cc(F)ccc2n1Cc1cccnc1 +Cc1occc1C(=O)N1CCC2(CC1)CCN(c1ccsc1)C2=O +CC(Oc1ccc(F)c(F)c1)C(=O)N(CC(N)=O)C1CCCC1 +CCCn1c(-c2cccc(C)c2)nnc1S(=O)(=O)CC(N)=O +CC1CCCN1S(=O)(=O)c1cc(Br)cnc1N +COc1ccccc1C(=O)NCC(=O)NCC1Cc2ccccc21 +Cc1ccc(C2(Cc3ccc4c(c3)OCO4)NC(N)=NC2=O)cc1 +Cc1noc(C)c1C(=O)N1CC2CC3CC(C2)CC1C3 +CCC(C)(C)NC(=O)CN1CCN(c2cc(C)nc3ncnn23)CC1 +Cc1c(C(=O)N2CCC(C(N)=O)CC2)nnn1Cc1ccccc1 +CCn1nccc1CNc1ccccc1-n1nccc1C +COc1cccc(CNC(=O)CCOc2ccccc2F)c1 +Cc1ccc(N2C(=O)N(C)c3ccccc3S2(=O)=O)cc1 +CCCN(Cc1ccsc1)C(=O)c1ccc(Cl)cc1 +CCCNc1ccnc(C(=O)N2CCCC2CC)c1 +CNC(=O)CN(C)c1ncnc2c1oc1ccccc12 +O=C(Cn1cnnn1)Nc1ccccc1OC(F)F +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)CC(=O)N3C)cc1C +CC(Cc1ccccc1F)NC(=O)C1CC(=O)N(C2CCCC2)C1 +CCCc1c(C(=O)NC2CC2)cnn1-c1ccccc1C +CCOc1cc(C(=O)NCc2ccnc(OC3CCC3)c2)ccn1 +O=c1c2nnc3ncnn3c2ccn1C1CCCC1 +O=c1[nH]c(=O)n(-c2ccccc2)c2c1CN(Cc1cccnc1)CN2 +CCc1ccc(C(O)CCCC(=O)N(C)c2ccccc2)cc1 +Cc1ccn(C(C)CC(=O)Nc2cccc(Cl)c2)n1 +CCOC(=O)CC1(NC(=O)OC(C)(C)C)COC1 +CNc1cc(-c2nc(CCN3CCCC3=O)no2)ccn1 +O=C(NCC(F)(F)F)c1coc(COc2cccc(F)c2)n1 +CCc1nccn1-c1cccc(C2CCCN(C(=O)C3CCC3)C2)n1 +CC(=O)Nc1ccc(O)c(C(=O)N(C)Cc2cc(C)on2)c1 +O=C(NCCc1nc(-c2ccncc2)n[nH]1)c1cccc2cccnc12 +Cc1ccsc1C(=O)NC(CNC(=O)OC(C)(C)C)C1CC1 +Cc1cc(=O)c2cccc(C(=O)NCc3ccccc3)c2[nH]1 +Cc1ccsc1C(=O)OCc1nc(N)nc(Nc2ccccc2)n1 +Cc1noc(CCNC(=O)NC(C)c2cc3cc(Cl)ccc3o2)n1 +COc1ccc(NC(=O)Cc2ccc(C)cc2)cn1 +Cc1ccc(C(=O)NCC(O)c2ccc3c(c2)CCO3)c(C)c1 +CN(Cc1ccccc1N1CCOCC1)c1ccc2nnnn2n1 +CC(C)NC(=O)N1CC(c2nc(-c3ccncc3)no2)C1 +CCOc1cc(Cl)ccc1C(=O)Nc1ccc2nncn2c1 +Cc1nc(C)n(C(C)CNC(=O)Cn2ccc3ccc(F)cc32)n1 +CCCNc1ccccc1S(=O)(=O)NCC(N)=O +O=C(NC(c1nccs1)C1CC1)c1ccc(-c2cscn2)cc1 +Cc1ccccc1OCC(C)NC(=O)C(C)NC(N)=O +COc1ccc(NC(=O)Cc2ccc(C)s2)cc1 +O=C1COCC1Cc1cccc(Br)c1 +CCOC(=O)c1c(C)[nH]c(C(=O)NC2CCC(C)CC2)c1C +NC(=O)c1cccc(NCc2cccc(Cl)c2)c1 +O=C(Nc1nc(-c2ccccn2)cs1)c1scnc1C1CC1 +COC(=O)C(c1ccccc1F)N1CCOCC1 +Oc1cccc(C2Nn3c(COc4ccccc4)nnc3S2)c1 +Cc1sc(-c2ccco2)nc1C(=O)N(C)C1CCCC1 +Cc1occc1-c1nnc(SCCOC(C)C)n1C +CS(=O)(=O)N1CCCC(C(=O)N2CCOCC2)C1 +COc1ccc(-c2nc3cc(Cl)cnc3n2CCC#N)cc1 +CCOC(C)c1noc(CN2Cc3ccccc3CC2C(N)=O)n1 +CCc1cnc(CN(C)C(=O)NC2CCCc3c2cnn3C)s1 +Cc1nn(-c2ccc(F)cc2)c(C)c1CC(=O)NCc1cscn1 +COC(=O)C1=C(C)N(C)C(=O)N(C)C1c1ccc(O)cc1 +CN(CC(=O)N(C)C1CCCCC1)C(=O)c1cnccn1 +CCOc1cc(NCc2ccc(C)cc2)nc(COC)n1 +Cc1ccccc1-c1nn(CCO)c(N)c1-c1nc2ccccc2[nH]1 +Cc1[nH]ccc1C(=O)N1CCC(=Cc2ccccc2)CC1 +COCCn1c(C)cc(C(=O)CN(C)c2ccccc2)c1C +CC(Cc1ccco1)NC(=O)C1(C)CC1(Cl)Cl +COc1cccc(CNCC(O)c2ccc(F)cc2)c1 +Cc1ccc(S(=O)(=O)CC(=O)N2C(C)CCCC2C)cc1 +CC(=O)N1CCC(CC(=O)N(C)CC2(C)CCOCC2)CC1 +NC(=O)C1CCCN1C(=O)c1cn(-c2cccc(Cl)c2F)nn1 +O=C1CC(c2nc(-c3ccc4c(c3)OCO4)no2)CN1c1ccccc1 +C#CCN1CCN(C(=O)NCCC(=O)NC(C)C)CC1 +CCNC(=O)c1cccc(CNC(=O)c2ccnc(NCC)c2)c1 +COc1ccc(Cl)cc1C(=O)N1CCc2c(nc[nH]c2=O)C1 +O=C(NCC(=O)N1CCC2(CC1)OCCO2)c1cccc(Cl)c1 +CC(O)CN1CCN(C(=O)COCCc2ccccc2)CC1 +CCCCC(=O)NCCc1c[nH]c2cc(F)ccc12 +Cc1noc(C)c1CCCNC(=O)Nc1nnc(C(F)F)s1 +Cc1cnc(NC(=O)CCOc2ccccc2F)s1 +O=C(COc1ccc(-c2nnco2)cc1)NCCc1ccc(F)cc1 +Cc1cncc(C2CCN(c3ncccn3)CC2)n1 +Cc1cccc(-c2cncc(C(=O)NC3CC3)c2)c1 +N#CC1CN(C(=O)COC2CCCC2)CCN1Cc1ccccc1 +Cc1nc(CNC(=O)COCC=Cc2ccccc2)c(C)s1 +O=C(N1CCCC1)C1(c2ccc(Br)cc2)CCOCC1 +O=C(Nc1ccccc1N1CCOCC1)c1cc(Cl)ccc1F +CCN(CC)C(=O)COc1ccc(C(=O)C(C)C)cc1N +OCCc1csc(COc2cccc(F)c2)n1 +COc1c(F)cccc1C(=O)N(C)Cc1nc(-c2ccccn2)no1 +CC(NS(=O)(=O)c1ccccc1-c1ccccc1)c1ccncc1 +CC1Oc2ccc(NC(=O)NC3CCc4ccccc43)cc2NC1=O +CC(c1ccccc1F)N(C(=O)NC1CCC(=O)N(C)C1)C1CC1 +O=C(CN(CCO)c1ccccc1)Nc1ccc(F)cc1F +COc1cc(NC(=O)c2coc(C)n2)c(OC)cc1Cl +CCC(C(=O)OC(C)C)N1CC(C)Oc2cccc(N)c21 +Nc1ccc(-c2csc(NC(=O)Cc3ccccc3)n2)cc1 +C=C(C)CN(CC)C(=O)COc1ncnc2ccccc12 +CC1Cc2ccccc2N1CC(=O)NCc1cccs1 +O=C(NCc1cscn1)NCC1CC=CCC1 +COc1ccc(NC(=O)c2ccc3c(c2)CCCC3)cn1 +Fc1cc(CN2CCCCC2c2ncc[nH]2)ccc1OC(F)F +COC(=O)CC(NC(=O)c1cnc2ccc(C)cn12)c1cccs1 +Cc1cc(C(=O)N2CCCC(n3cncn3)C2)no1 +Cc1nn(C)c(C)c1CCC(=O)N1CCC(C)(O)C(O)C1 +CCOc1ccc(OCC)c(-c2cc(C(=O)OC)n(C)n2)c1 +CC(=O)Nc1cccc(NC(=O)c2cccnc2SC(F)F)c1 +OC(c1ccc(F)cc1)c1nc2ccccc2s1 +O=c1c2c3c(sc2ncn1CCc1ccc(F)cc1)CNCC3 +Cc1nn(-c2ccc(F)cc2)c(C)c1S(=O)(=O)N1CCCCC1 +CNC(=O)NCC(=O)NCc1cnn(-c2ccccc2)c1 +O=C(CNC(=O)c1ccnc2[nH]ccc12)Nc1ccc(F)cc1 +COCCNC(=O)Cn1ncc2cccn2c1=O +Cc1c(Cl)cccc1S(=O)(=O)N1CCN(CC2CC2)CC1 +OCc1nnn(Cc2cccc(F)c2)c1Cc1cccs1 +O=C(NC1CCCC1)C12CC3CC(C1)CC(n1ncnn1)(C3)C2 +CC(C)OCc1cccc(CNC(=O)C2CNC(=O)N2)c1 +COC1CCN(C(=O)NCc2cccc(F)c2)C1Cc1ccncc1 +CCc1onc(C)c1NC(=O)N1CCN(CCOC(C)C)CC1 +CC(=O)N1CCC(NC(=O)c2nc(C)n(-c3ccc(F)cc3)n2)CC1 +O=S(=O)(NCCc1ccc(O)cc1)N1CCCC1 +CS(=O)c1cccc(NC(=O)c2c[nH]nc2-c2ccccc2)c1 +CC(C)(C)OC(=O)NCC(N)c1ccccc1C#N +COc1ccc(CNC(=O)NCc2cnc(C)s2)cn1 +Cc1cc(N2CCCC(n3cc(C(=O)NCCO)nn3)C2)nc(N)n1 +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1ccc2c(c1)C(=O)NCC2 +CCCCc1nc(C)cc(NCCn2cnnc2)n1 +Cc1nn(-c2ccc(F)cc2)c(-n2cccc2)c1C(=O)NC(C)(C)C +COCC(O)CN(C)C(=O)c1ccccc1OC +CCOCCCNC(=O)C1CCCN(C(=O)c2[nH]c(C)cc2C)C1 +Cc1nc2c(C#N)cnn2c(C)c1CCC(=O)NCCO +CC1C(=O)NCCN1C(=O)c1ccc2[nH]cnc2c1 +CC(C)C(=O)N1CCCN(C(=O)C(C)C)c2ccccc21 +CCOCCC(=O)NCCN1CCCS1(=O)=O +COC(=O)c1cccc(C(=O)NCCc2ccncc2)c1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)N1CCCCC1 +COc1ccc(C(=O)NCc2ccc(-n3nc(C)cc3C)nc2)nn1 +CCOc1ccccc1N1CCN(C(=O)c2ccoc2C)CC1 +N#Cc1ccc(C(=O)N(Cc2nccn2C(F)F)C2CC2)cc1 +COCCCNC(=O)C1c2ccccc2C(=O)N1Cc1ccco1 +CN(C)C(=O)N1CCN(c2cn[nH]c(=O)c2Cl)CC1 +Cc1nc(Cn2c(N)nc3c(F)cccc32)cs1 +CC(C)NC(=O)c1ccc(NC(=O)c2ccc3cncn3c2)cc1 +COc1ccccc1OCCc1nc(C(C)(C)O)cs1 +COc1ccc(OC(C)C(=O)N(C)Cc2ccc3c(c2)OCO3)cc1 +CC(C)(C)OC(=O)N1CC2COCC(C1)C(=O)N2 +O=C(NCCc1ccc(O)cc1)c1[nH]nc2c1CCCC2 +COCc1cc(=O)n(CC(=O)Nc2cccc(OC)c2)c(N)n1 +Cc1cccc(OCC(=O)NC(C(N)=O)c2ccccc2)c1 +COc1ccccc1C(C)NC(=O)c1cc(-c2cccs2)n[nH]1 +CN(CCCc1ccccc1)c1ncnc2c1cnn2CCC#N +Cc1cc(C(C)(C)C)cc(C)c1S(=O)(=O)N1CCNC(=O)C1 +N#Cc1cccc(C(=O)c2ccnc3ccccc23)c1 +CCNS(=O)(=O)c1ccc(NC(=O)C2CCCO2)cc1 +CNC(=O)C1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +COCCNC(=O)CNC(=O)c1cc(F)ccc1Br +O=C(COc1ccccc1Cl)NCc1ccncc1 +CCOC(=O)Nc1nc(CC(=O)NC(C)c2ccccc2)cs1 +O=C(C1CC2C=CC1C2)N1CCc2c(nc(-c3ccccn3)[nH]c2=O)C1 +Cc1cccc(OCCNC(=O)c2cnc3n(c2=O)CCS3)c1 +CC(NC(=O)c1cccc(NC(N)=O)c1)c1ccc(F)c(F)c1 +Nc1cccnc1SCC(=O)Nc1ccccc1Br +Cn1c(=O)c2[nH]c(N3CCN(c4ncccn4)CC3)nc2n(C)c1=O +CN(C(=O)c1cscn1)c1ncccc1Br +COc1cccc(NC(=O)C(C)(C)C)c1C(C)O +CC(=O)Nc1cc(NCC(=O)N2CCCCC2)ccc1C +CCCc1n[nH]cc1C(=O)N(C)CC1CCN(c2ccccc2)C1 +CCC(CC)c1nnc(NC(=O)CCn2cnc3ccccc32)s1 +Cc1ccc(C)c(CNC(=O)Cn2cnc3onc(C)c3c2=O)c1 +CC(C)Oc1ccc(-n2ccnc2SCCO)cc1 +Cn1ncc(C(=O)Nc2ccc(C(C)(C)C)cc2)c1N +CCCOC(=O)CC(C)c1c(C)n(C)c(=O)n(C)c1=O +CCN1CC2(CCC1=O)CCN(c1ncncc1C(C)C)CC2 +Cc1noc(CCCNC(=O)CNC(=O)c2cc3ccccc3[nH]2)n1 +CCN(C)C(=O)NCCc1cccc(C(=O)OC)c1 +CC(Sc1nc2ncccn2n1)C(=O)c1ccc(Cl)cc1 +Cn1cc(C(=O)NCc2ccc(-c3ccccc3C#N)cc2)cn1 +CCCOc1ccc(C(=O)NCc2ccc(C)cc2)cc1N +O=C(NCC1COc2ccccc2C1)NC1CCCC1 +Nc1nc(SCC(=O)N(Cc2ccccc2)CC(F)(F)F)n[nH]1 +Cc1ccc(CCC(=O)NCC(=O)N2CC(C(N)=O)CCC2C)cc1 +CC(C)COC1CCN(C(=O)CC(C)c2ccccc2)CC1 +CN(C(=O)Cc1nc2ccc(N)cc2o1)C1CCCCC1 +Cc1cc(C2CCCN2C(=O)c2cc(C3CCCCC3)no2)no1 +C=CCN1C(=O)CNC12CCN(C(=O)c1ccc(C)cc1)CC2 +COc1ccc(C)cc1-c1nnn(-c2ccccc2C)c1N +CCc1c(C(=O)OCc2nc(C)no2)nnn1-c1cccc(Cl)c1 +CCCC(=O)Nc1cccc(C(=O)N(CC)CC)c1 +Cn1ccc(C(=O)N2CC(=O)Nc3ccccc32)n1 +Cc1cc(-c2ccc(Cl)cc2)c2c(N)noc2n1 +CC(C)c1cc(CN(C)C(=O)c2cnn3ccn(C)c23)on1 +CCc1nc(N2CCC(Oc3ccccc3OC)CC2)no1 +O=C(NCC1CC1)c1c(F)cccc1C(F)(F)F +Cc1nc2c3ccccc3n(Cc3ccccc3Cl)c(=O)n2n1 +c1cnc2nc(SCc3nc(C4CC4)no3)nn2c1 +Nc1c(-c2ccccc2)nc(O)n1Nc1ccccc1 +COc1cc(C)c(S(=O)(=O)Nc2cn[nH]c2)cc1C +CCOc1ccc(C(O)CNc2c(C)cccc2CC)cc1 +CSc1cc(C(=O)NCc2cnn(Cc3ccccc3)c2)ccn1 +CN(Cc1ccc(O)cc1)C(=O)CC1CCCCC1 +CC(Nc1nnnn1-c1ccccc1)c1ccc(C#N)cc1 +Cc1nc2ccc(N)cn2c1CC(=O)N1CCCCCC1 +CCN(Cc1noc(CC(C)C)n1)C(=O)Cn1ccccc1=O +O=C(NCC1(O)CCCCCC1)c1ccnc(OC2CCC2)c1 +CC(C)Oc1ccc(CNC(=O)NCC2CC2C)cc1 +Cc1cc(C(=O)N2CCCC2c2noc(C)n2)c(C)o1 +Cc1ccc(C(=O)CSc2cc(C#N)ccn2)c(C)c1 +Cc1ccnc(NCCCc2nc3ccc(F)cc3[nH]2)n1 +CC(=O)Nc1cc(S(=O)(=O)Nc2ccccn2)ccc1C +Nc1cc(=O)n(Cc2ccccc2)c(=O)n1-c1ccc(F)cc1 +Cc1ccc(C(O)CNC(=O)Cn2c(=O)oc3ccccc32)o1 +CC(=O)NC(C(=O)Nc1cccc(C)n1)C1CCCC1 +Cc1ccc(CC(=O)NCc2ccccc2CN2CCOCC2)cc1 +NC1C(=O)N(Cc2ccccc2Cl)c2ccc(F)cc21 +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1cccnc1 +CCCC(=O)N1CCCC1C(=O)Nc1cc(C)cc2cccnc12 +CC(CCc1ccccc1)CC(=O)Nc1ccc(=O)n(C)c1 +CC(C)NC(=O)c1cc2cc(N(C)S(C)(=O)=O)ccc2s1 +Cc1ccc(F)c2c1N(C(=O)c1cnn(C)c1C(F)F)CCC2 +COc1ccc(NC(C)=O)c(NC(=O)c2csc3c2CCCC3)c1 +Cc1ccccc1CC1(c2cccc(Cl)c2)NC(N)=NC1=O +O=C(c1cc(-c2cccc(Cl)c2)on1)N1CCOCC1C1CC1 +COc1ccc(C(=O)NCc2cc[nH]c(=O)c2)cc1OC(F)F +CCc1ccc(-c2n[nH]c(SCc3nccn3CC)n2)cc1 +CC(=O)NCCNC(=O)c1c[nH]nc1-c1cccc(F)c1 +Cc1ccc(Cn2nc(C)c(Nc3nc(=O)c(C)n[nH]3)c2C)cc1 +Cn1cnnc1C1CCCN(Cc2ccsc2)C1 +CC1CCc2noc(NC(=O)c3ccccc3)c2C1 +CN(C)c1ccccc1C#CCNC(=O)c1cc(-c2ccco2)on1 +Cc1nc(C(C)C)ncc1C(=O)NCc1ccc(OC(C)C)cc1 +CC(C)CC(=O)Nc1ccc(S(N)(=O)=O)cc1 +N#CC(NC(=O)c1cnns1)c1cccc(Cl)c1Cl +CCOC(=O)CC1(CNC(=O)c2ccnnc2)CCCCC1 +Cc1cccc(C)c1NC(=O)OCCc1ccccn1 +Cc1cc(NC(=O)COc2c(Cl)cccc2Cl)on1 +Cc1ccc(S(=O)(=O)n2cc(Cl)c(=O)c3ccc(C)cc32)cc1 +CCCCNC(=O)c1ccnc(-c2ccc(C)s2)c1 +NS(=O)(=O)CCNc1c(F)c(F)c(F)c(F)c1F +COc1nc(C)cc(C)c1CN1CC(=O)N2CCC(O)CC2C1=O +CCOC(CC)C(=O)Oc1ccc(C(=O)N(C)C)cc1 +CC(=O)c1ccc(NC(=O)c2coc(S(N)(=O)=O)c2)cc1C +CC(C)C(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 +CC(Oc1ccc(N)cc1F)C(=O)N1CCOCC1 +CC1CN(CCC(=O)Nc2ccc(F)c(N)c2)CC(C)O1 +CC(C)(C)c1ccc(OCC(=O)Nc2nnc[nH]2)cc1 +Cc1nc2cccnc2n1-c1cc(N)ccc1Cl +Cc1ccc(C(C)C)c(OCC(=O)Nc2nc(C)no2)c1 +O=C1COc2ccc(C(=O)N3CCCC3C3CCCCC3)cc2N1 +CN(C)c1ncccc1NC(=O)c1ccc(Br)cc1 +Cc1ccc(S(C)(=O)=O)cc1NC(=O)C1CC2C=CC1C2 +C=CCNC(=O)CSc1nnc(-c2cccc(C)c2)n1CC +CCOCC1CCCN(C(=O)c2ccc(C(F)(F)F)cc2)C1 +CCN(CCO)C(=O)COc1ccc(Cl)c(Cl)c1 +O=C(CNC(=O)Cc1cccc2ccccc12)NCc1cccs1 +CC(C)C(=O)NCC(=O)N1CCC2(CC1)Cc1ccccc1C2=O +C=CCN(Cc1nccn1Cc1ccccc1F)C(=O)C1CCC1 +CCC(NS(=O)(=O)c1cn[nH]c1C)c1cccs1 +CN(C)C(=O)c1ccc(OCCCOc2ccc(C#N)cc2)cc1 +CCn1cc(C2CCN(C(=O)Nc3cnccc3C)CC2)cn1 +O=C(c1ccc(O)c(Cl)c1)N(Cc1cccc(F)c1)C1CC1 +Cc1ccc(NC(=O)COc2cccc(N)c2)cc1C +CCc1nnc(NC(=O)NC(C)c2ccc(OC)c(F)c2)s1 +O=c1c2c([nH]c3cc(-c4cccs4)nn13)CCC2 +Cc1cccc(CS(=O)(=O)NCCN2CCOCC2)c1 +c1ccc2c(-c3csc(NC4CC4)n3)c[nH]c2c1 +O=C(c1cc2ccccc2o1)N1CC(c2nc(-c3ccco3)no2)C1 +Nc1ccc2c(c1)N(C(=O)Cc1ccc(Cl)cc1)CC2 +Cc1cccc2c1C(=O)N(C)C(c1ccccn1)N2 +CCCc1nnc(NC(=O)C2CC(=O)N(C3CCCC3)C2)s1 +Nc1nonc1C(=O)NCc1ccc(O)c(F)c1 +CCCNC(=O)Cn1cc(Br)c(=O)[nH]c1=O +CCCCN(C)C(=O)c1cc(=O)c2cc(N)c(C)c(C)c2o1 +COc1ccc(C)cc1NC(=O)NCc1ccnc(OCC2CC2)c1 +CC(=O)Nc1cc(C(=O)Nc2cccc3cn[nH]c23)ccc1C +CCCNC(=O)CCNC(=O)Cn1ccc2ccc(Cl)cc21 +CCCNC(=O)Nc1cccc(C(=O)N2CCCC2)c1 +Cc1nnc(C(C)N2CCN(C(=O)c3cc4ccccc4[nH]3)CC2)o1 +CC(NC(=O)CCn1ccnn1)C12CC3CC(CC(C3)C1)C2 +CCS(=O)(=O)c1ccc(NC(=O)OC(C)(C)C)cc1 +CCOc1cc(NCCc2c[nH]c3ccccc23)nc(CC)n1 +CN(C)c1ccc(C#CCNC(=O)c2ccccc2)cc1 +CC(NC(N)=O)C(=O)NC(C)c1ccc(Cl)c(Cl)c1 +Cc1ccc(-c2c(C)sc3[nH]c(=O)[nH]c(=O)c23)cc1 +CC(=O)c1csc(C(=O)OCc2cc(C)nc(C)n2)c1 +COc1cc(F)c(NC(=O)N(C)C(C)CC#N)cc1OC +O=C(Cc1c[nH]c2ccccc12)Nc1ccc2c(c1)NC(=O)CO2 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)NCc2ccc(C)cc2)c1 +Cn1nnc2c1CCN(C(=O)Cc1ccccn1)C2COCC1CC1 +Cc1ccccc1NC(=O)CCc1c(C)nn2cnnc2c1C +COc1ccc(CCC(=O)N2CCC(C)CC2C)cc1OC +O=C(NCCOc1ccc(Cl)cn1)Nc1cccnc1 +CC(C)n1nnnc1-c1ccccc1NC(=O)C1CCOC1 +CNC(=O)c1cc(C)ccc1NC(=O)CSc1ccccc1F +Nc1ccccc1N1CCC(OCc2cccc(F)c2)CC1 +CCc1noc(C)c1C(=O)N1CC(C(=O)N2CCCCC2)C1 +Cc1nc(-c2cccc(NCc3cc4ccccc4o3)c2)n[nH]1 +CCOC(=O)CSc1nnc(-c2ccc(C)cc2)n1C +CCOCCC1(CNC(=O)N2CCCC(O)C2)CCCC1 +CC(C)OC(=O)c1ccc(CC(=O)c2ccc(O)cc2O)o1 +COCC1(NC(=O)CCc2ccncc2)CCCC1 +CSc1ccccc1NC(=O)c1c[nH]c2ccccc12 +N#Cc1ccc(NC(=O)CCC(C#N)c2ccccn2)cc1 +CC(=O)Nc1ccc(NCc2cccc(Br)c2)cc1 +O=C(c1cnns1)N(CCO)C1CCCCC1 +CC(=O)Nc1cc2c(cc1Cl)-c1ccc(F)cc1C2O +O=C(NCC1CCCO1)c1ccc(OCc2ccccc2)cc1 +CCCC(C)NC(=O)C(C)Sc1nc(C)c(C)o1 +CCN(CCO)C(=O)C(C)NC(=O)c1ccoc1 +COc1cccc(CC(=O)N(CCCO)C(C)C)c1 +O=C(NCc1ccnc(-n2cccn2)c1)C1Cc2ccccc2O1 +COc1ccc(NC(=O)Cc2ccc(-n3cccc3)cc2)cc1OC +C#CCN(CC(F)(F)F)C(=O)c1ccc(F)c(OC)c1 +Cc1cccc(NC(=O)CN(C)C(=O)c2c(C)cc(C)[nH]c2=O)n1 +Cc1cccc(C)c1NC(=O)CCCSc1nnnn1C +CN(C)C(=O)c1ccc(C(=O)Nc2cnn(C)c2)cc1 +OCCCn1c(-c2cccc(F)c2)nc2cc3c(cc21)OCO3 +COc1ccccc1C(C)NC(=O)Cc1ccc(C)s1 +CCS(=O)(=O)N1CCC(c2ccc3c(c2)OCO3)CC1 +CN(C(=O)c1cccc(CC#N)c1)c1ccccc1 +Cc1cccc(Cn2nc(C)cc2NC(=O)Cn2nnnc2N)c1 +CC(NC(=O)NC1CCCCCC1)c1nncn1C +COc1ccc2c(c1F)C(CC(C)(C)C)NCC2 +Cc1ncc(-c2ccc(S(=O)(=O)N(C)Cc3ccco3)cc2)o1 +Cc1cc(-c2nc(CC(=O)Nc3ccccc3)no2)c(C)n1C1CC1 +COc1ccc(S(=O)(=O)Cc2ccccc2F)cc1 +COc1ccc(COC(=O)c2ccccc2-c2nnc(C)o2)cc1F +O=C1Nc2ccccc2SCC1CC(=O)N1CCOCC1 +CCC(OC(=O)c1nccnc1N)C(=O)Nc1ccccc1 +COc1ccc(C(O)CCc2nccs2)c(OC)c1 +COC1OC(COC(=O)c2ccccc2)CC1F +Cc1ccc(OS(=O)(=O)c2ccc3[nH]c(=O)[nH]c(=O)c3c2)cc1C +CN(C)c1nc(N(C)C)n(C(=O)c2ccc(F)cc2)n1 +COc1ccc(NC(=O)CCNc2ncnc3[nH]cnc23)cc1Cl +COc1ccc(C)cc1CCOc1cc(C)c(N)cn1 +NC(=O)c1ccccc1OCC(=O)c1ccccc1 +COc1ccc2nc(N(Cc3ccco3)C(C)=O)sc2c1 +CNC(=O)NCC(=O)N(Cc1ccccc1)CC(F)F +COC(=O)CCC(=O)N1CCCC(Nc2ccc(C)c(C)c2)C1 +CC(C)(C)NC(=O)c1cccc(NC(=O)Cc2ccccc2)c1 +COc1ccc(C(=O)Nc2c(C)nc3c(C)cccn3c2=O)cc1 +CC(NC(=O)NCCNc1cnccn1)c1cc(F)ccc1F +O=S(=O)(c1cccc(Cl)c1)N1CCN(CC2CC2)CC1 +C=CCOc1ccccc1-c1c(C#N)c(N)nc2c1COCC2 +CCCCOC(=O)c1ccc(N2CCNC2=O)cc1 +CN(CC1CCCCO1)C(=O)NCC(=O)Nc1ccc(Cl)cc1 +COC(=O)CSc1nnc(-c2cccc(Cl)c2)o1 +CC(NC(=O)Nc1ccc(F)cc1)c1ccc(S(N)(=O)=O)cc1 +O=C(CNC(=O)c1cccs1)NC1(c2cccc(Cl)c2)CC1 +CCc1ccc(NC(=O)C(C)Sc2nccn2C)cc1 +Nc1ccc(C(Cc2cccs2)C(=O)N2CCCC2)cc1 +CC(C)C(=O)N1CCC(Cc2cnc(Nc3cnccn3)cn2)CC1 +COc1ccc(Br)c2ccnc(C#N)c12 +Cc1cc(Br)cnc1NC(=O)c1ccncc1 +CC(C)Cn1cc(NCc2cnn(-c3ccccc3)c2)cn1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NC2CCCCCC2)[nH]n1 +CCCCc1nnc(NC(=O)NCCc2ccccc2)s1 +CCC1CCN(C(=O)Nc2cnn(CCOC)c2)CC1 +CCn1nc(C)c(CNS(=O)(=O)c2ccc(C)cc2C)c1C +COc1ccc(NC(=O)c2nn(C)c3ccccc3c2=O)cc1OC +Cc1cc(NCc2nncn2C)ccc1C(=O)OC(C)(C)C +O=C(CCNS(=O)(=O)c1cccs1)NC1CCCCC1O +CC(COc1ccc(F)cc1F)NC(=O)Cc1cccs1 +O=C1N(Cc2ccccc2)c2ccccc2C1(O)c1ccccc1 +CC(=O)N1CCCC(C(=O)NCC(C)N2CCc3ccccc32)C1 +O=C(CCCn1cncn1)Nc1cccnc1N1CCCC1 +O=C(c1c2ccccc2nc2ccccc12)N1Cc2cncnc2C1 +Cc1cc(=O)[nH]c2ccc(CC3CCCCO3)cc12 +COc1ccc(OCC(=O)NC(C)c2ccc(F)cc2)cc1 +O=C(NCCN1CCN(C(=O)c2cc[nH]n2)CC1)c1ccccc1F +Cc1cnc(C(=O)N2CCOc3cc(F)ccc32)cn1 +CCc1ccc(C2CCCN2C(=O)NCc2ccc(C)nc2)o1 +Cn1cc(C2CN(S(=O)(=O)Cc3cccc(C#N)c3)CCO2)cn1 +CCCC(=O)Nc1cccc(CNC(=O)NC(C)C(C)C)c1 +COC(=O)NC(C)(C)C(=O)NCc1ccc(OC2CCCCC2)nc1 +CCOC(C)c1ccc(-c2cncc(C(N)=O)c2)cc1 +CCOC(=O)CSc1n[nH]c(=O)n1-c1ccccc1 +COCc1ccc(CNC(=O)c2c(C)nn(C)c2OC)cc1F +Cc1cc2nc(-c3ccccc3)cc(NCCCN3CCCC3=O)n2n1 +NC(=O)c1ccc(C(=O)Nc2cc(C3CC3)nn2-c2ccccc2)cc1 +COC(=O)c1ccc2c(c1)nc(C(C)=O)n2C(C)C +CC(C)(C)NC(=O)CNS(=O)(=O)c1cccc(Cl)c1F +C#CCOc1ccccc1OCc1nc(C)cs1 +O=C(NCCCOCC1CCCO1)N1CCOCC1C1CC1 +Nc1nccnc1C(=O)N1CCc2ccc(O)cc2C1 +Cc1cccc2[nH]cc(CC(=O)Nc3ccc4[nH]nc(C(N)=O)c4c3)c12 +COc1ccc(OCC(=O)Nc2cc(C)nn2C(C)(C)C)cc1OC +Cc1cc(=O)[nH]c2cc(NC(=O)CC(C)C)ccc12 +CCNC(=O)NCC1(Sc2ccccc2)CCOCC1 +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)Nc1ccc(F)c(F)c1 +COc1ccc(OC)c(C=Cc2nc(C(C)(C)NC(C)=O)no2)c1 +COC(=O)C(C)CN(C)C(=O)CSc1cccs1 +N#Cc1c(-c2ccc(F)cc2)nn(-c2cc(F)ccc2F)c1N +N#Cc1cccc(-c2nn3c(C#N)nnc3s2)c1 +c1ccc(COc2cc(CN3CCOCC3)on2)cc1 +CC(NC(=O)N1CCOCC1C1CC1)C(=O)N1CCCCC1 +COCCNC(=O)c1ccc(Cl)c(NC(=O)C(C)C)c1 +CCCCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1cccc(C)c1 +CC(=O)Nc1cnc2c(nc3cc(C)ccn32)c1C +NC(=O)CCCNC(=O)c1cc2ccccc2cc1OC(F)F +CCN(CCC(F)(F)F)C(=O)COc1ccc(F)cc1 +OCCCc1csc(COc2ccccc2Cl)n1 +CC(C)CNC(=O)c1cccc(S(=O)(=O)N2CCN(C)CC2)c1 +CCCCC(=O)N1CCc2cc(OC)c(OC)cc2C1 +CCNC(=O)CN(CC)C(=O)NCc1ccc(-n2ccnc2)c(F)c1 +CN(C)C(=O)N1CCN(C(=O)c2ccccc2F)CC1 +Cc1nc(N2CCOCC2)[nH]c(=O)c1CCC(=O)Nc1ccn(C)n1 +CC(C)c1n[nH]c(-c2nc(-c3ccncc3)no2)c1Br +Brc1ccccc1Oc1ncccn1 +CCOc1ccccc1NC(=O)Nc1cnn(C2CCOCC2)c1 +CSc1ccc(CN(CCO)C(=O)c2ccncc2Cl)cc1 +CC(=O)c1ccc2[nH]c3ccc(C(C)=O)cc3c2c1 +Cc1nnc(SC(C)C(=O)N2CCc3ccccc32)n(N)c1=O +COCCOc1cccc(C(=O)NCc2cccc(C)n2)c1 +COc1ccc2sc(NCc3ccncc3)nc2c1 +Cc1csc(C(C)NCC(=O)Nc2nccs2)n1 +O=C(c1cncs1)N1CCC(c2cc3cccnc3[nH]2)CC1 +O=C(CCC1CCCCC1)N1CCN(Cc2ccncc2)CC1 +Cc1ccc(S(=O)(=O)Nc2ccncc2N)cc1 +CC1CCCCC1NC(=O)c1onc(-c2ccccc2)c1N +COc1cc(-c2noc(-c3scnc3C3CC3)n2)ccn1 +CC(=O)N1CCN(C(=O)CNC(C)c2ccc(Cl)cc2)CC1 +N#Cc1ccccc1NC(=O)COc1ccc(F)cc1F +Cc1ccccc1-c1nnn(CC(=O)N2CCCC(C)C2)n1 +N#CCCCCC(=O)c1ccccc1Br +COc1ccc(CNC(C)C(=O)NC(C)(C)C)cc1OC +CCOC(=O)CN(C)C(=O)Cc1cccc(Br)c1 +N#CC(NC(=O)Cc1cccs1)c1cccc(Cl)c1 +CC(C)c1cc(N)c2onc(CC(=O)N(C)CCO)c2c1 +CC(C)CCNC(=O)C1CCN(C(=O)c2scnc2C2CC2)CC1 +Cc1cnn(CC2CCCN2C(=O)C2Oc3ccccc3OC2C)c1 +CC(C)CNC(=O)Cn1c(C(C)C)nc2ccccc21 +N#Cc1ccccc1Cn1nncc1-c1ccc(F)c(F)c1 +O=C(Cc1ccccc1)NCC(=O)NC1CCCC1 +O=c1[nH]c(C2CCOC2)nc2ccc(-c3ccccc3)cc12 +COc1ccc(OC)c(CC(C#N)C(=O)N2CCCCCC2)c1 +COc1ccc(NC(=O)Cn2ccc3ccccc3c2=O)cc1OC +CS(=O)(=O)N1CCCC1c1cccc2ccccc12 +Cc1cc(CNc2ccc(C(=O)N3CCCCC3C)cc2C)no1 +O=C(Cc1c(F)cccc1F)Nc1ccc(N2CCNC2=O)cc1 +Cc1ccnc2nc(C(=O)Nc3cccc(C(F)(F)F)c3)nn12 +Cc1ccccc1NC(=O)CNc1cccc(C)c1C(N)=O +COc1cccc(NC(=O)Nc2nnc(C(C)C)s2)c1 +COC(=O)CCCNC(=O)C(N)c1cccc(C)c1 +Cc1[nH]ncc1CCCNc1nc2ccccc2s1 +O=C(CCc1ccncc1)NC1CCCCNC1=O +CCOC(=O)c1ccc(N2CCCC2c2nncn2CC(C)C)nc1 +CSc1cccc(NC(=O)c2cn(C)c3ccccc23)c1 +Cc1ccc2[nH]c(CN3CCC(c4nc[nH]n4)CC3)cc(=O)c2c1 +O=C(Cc1ccc(F)cc1F)Nc1nc(-c2ccco2)cs1 +O=C(CCOCC1CCCO1)Nc1cccc2cnccc12 +Cc1csc(SCC(=O)NCCCN2CCCCCC2=O)n1 +O=C(NCc1ccc(C(=O)N2CCCC2)cc1)Nc1ccccc1F +O=C(Nc1ccc2c(c1)COC2)N1CC2C3CCC(O3)C2C1 +CCCOC(=O)c1nnn(-c2ccccc2OCC)c1C +Cc1cccc(COC2CCN(c3ccccc3N)CC2)c1 +CC1CN(Cc2ccc(CNC(=O)C(C)C)cc2)CC(C)O1 +Cc1nn(C)c2cn(CC(=O)Nc3ccc4c(c3)OCO4)nc12 +CCCCNC(=O)c1ccccc1NC(=O)Cc1ccccc1 +COc1ccc(CNC(=O)NCC(C)C)cc1OC1CCCC1 +C=CCn1c(N)nnc1SCCOc1ccccc1C +CCCn1ncc(-c2ccc3c(c2)OCCO3)c(C#N)c1=O +CCCc1cc(NC2CCc3nc(CC)nn3C2)n2ncnc2n1 +COc1ccc(NC(=O)CSc2nc3c(N)ncnc3[nH]2)cc1 +NC(c1ccc2c(c1)CCCC2)C(F)(F)C(F)(F)F +CCCN1CCCC2(CCN(C(=O)CCc3n[nH]c(C)n3)C2)C1=O +Nc1ccccc1C(=O)NCCCNC(=O)c1ccco1 +CC(C)C(=O)Nc1ccc(NC(=O)c2cnc3ccccc3n2)cc1 +Cc1cccc(Cc2nnc(CCC(=O)NC3CCCCCC3)o2)c1 +C#CCN1C(=O)C(Cc2cccc(F)c2)Oc2ccc(N)cc21 +CSc1nnc(-c2ccc(NC(=O)OC(C)(C)C)cc2)o1 +Cc1ccc(OCC(=O)Nc2ccc(Cl)c(C)n2)cc1 +CC(C)n1c(-c2cccc(C(=O)NCC3CC3)c2)nc2cccnc21 +CC(=O)Nc1cc(NC(=O)C2CCN(C(=O)C(C)C)CC2)ccc1C +COC(=O)C(C)(Cc1ccc(OC)cc1)NC(=O)c1ccccc1 +CCN(CCC#N)S(=O)(=O)N(C)C1CCCCC1 +Cn1ncc2ccc(F)c(C(=O)NCC(C)(C)C)c21 +CCCNc1nc(-c2ccc(OC)cc2)ccc1C#N +CC1(NC(=O)CCN2CCCC2=O)Cc2ccccc2C1 +Cc1n[nH]cc1CNC(=O)c1ccccc1OC(C)C +Cc1ccc(CCNC(=O)NC2CCCC(C(F)(F)F)C2)cn1 +COc1cc(CN2C(C)COCC2C)cc(Cl)c1OCC(N)=O +Cc1c(CCNC(=O)NC2(C)Cc3ccccc3C2)cnn1C +OCCCCSc1nnnn1-c1ccc(Br)cc1 +CCC(CO)NS(=O)(=O)c1cc(C)c(Br)cc1C +O=C(Cc1ccc(NC(=O)c2ccno2)cc1)NCC(F)(F)F +C=CCn1c(SCC(=O)N2CCCC2)nnc1C1CC1 +Cc1ccc(-c2nnc(SCC(N)=O)o2)cc1C +CCCC1CN(C(=O)c2ccc3c(c2)nnn3C)CCO1 +Cc1nn(C(F)F)c(C)c1CC(=O)NC(Cc1ccccc1)C1CC1 +COc1ccccc1CSc1nnc2ccccn12 +C=CCCC(=O)NCC1CCN(C(=O)Oc2ccccc2)CC1 +CCCC(=O)NC1CCCN(C(=O)Nc2ccc(C(C)=O)c(C)c2)C1 +CCCCC(=O)Nc1ccc2c(c1)oc(=O)n2C(C)C +COc1cccc(CNC(=O)Cn2ccc3ccccc32)c1OC +CCC(C(=O)Nc1ccnn1C)n1nc(C(F)(F)F)c2c1CCC2 +CC(Cc1ccco1)NC(=O)N(C)Cc1nnc2n1CCC2 +Cc1nn(C)cc1C(=O)OCCCc1nc2ccccc2s1 +Cc1noc(C)c1CC(=O)Nc1cccc(CN2CCOC2=O)c1 +Cc1noc(C)c1NC(=O)NCCc1ccccn1 +N#Cc1c(F)cccc1NC1CCN(c2ncccn2)CC1 +CC(NC(=O)CC1NCCc2ccccc21)c1ccccc1 +Cc1nsc2ncc(C(=O)N3CCn4c(C)nnc4C3)cc12 +CCN(Cc1nc2cc(Cl)ccc2n1C)CC(C)C#N +N#Cc1ccc(OC2CCC(NC(=O)Cc3ccon3)CC2)nc1 +CCOC(=O)c1cc(NC(=O)Nc2ccccn2)c(C)nc1C +CC(=O)c1c(C)[nH]c(C(=O)C(C)Sc2nnnn2C(C)(C)C)c1C +CC1(C)C(=O)NCCN1C(=O)Cc1ccc(S(C)(=O)=O)cc1 +Cc1nn(C)c(C(=O)Nc2ccc(C(N)=O)cc2)c1Br +CCOCCOC(C)C(=O)N1CCCc2c(F)ccc(C)c21 +CC(c1cccs1)N(C)C(=O)Nc1ccncc1 +CCC(=O)Nc1cccc(OCC(=O)Nc2ccc(C)cc2)c1 +COc1ccc(NC(C)=O)cc1NC(=O)CCCc1cccs1 +C#CCNC(=O)Cn1nnc(-c2ccc(F)c(C)c2)n1 +COc1cccc(-c2cnn3ccccc23)c1OC +Cc1cc(C(=O)N2CCOC3CCCC32)c(C)n1Cc1ccco1 +CCc1ccc2nc(CCC(F)(F)F)[nH]c(=O)c2c1 +C=CCn1nc2ccc(S(=O)(=O)N3CCCC3)cn2c1=O +CC(C(=O)NCc1ccco1)n1c2ccccc2c2cn[nH]c(=O)c21 +COc1ccccc1OCC(O)CNc1ccc(C)cc1C +NC(=O)COc1cccc(CN2CCOCC2)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)C1CCC(=O)NC1 +CCOC(=O)c1cc(N)n(-c2cccc(C)c2C)n1 +CN(Cc1cccc(C#N)c1)S(=O)(=O)c1ccc2c(c1)OCCO2 +CCn1cnnc1CNC(=O)CCN1C(=O)C(C)Oc2ccccc21 +CN(Cc1nc(-c2cccnc2)no1)C(=O)c1cn2cccnc2n1 +COCCNC(=O)C1CCC(c2cccc(C)c2)N(C(=O)C2CC2)C1 +c1coc(CN(Cc2cccs2)c2ncnc3ccsc23)c1 +O=C(Cc1ccc2c(c1)CCCC2)Nc1nn2cnnc2s1 +CCc1nc(CNc2ccc(-n3cnnn3)c(C)c2)no1 +COC(=O)c1cccc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)c1 +Cc1c(C(=O)OC(C)C)nnn1-c1ccccc1F +CCCN1CC(C)Oc2ccc(C(=O)C(C)N)cc21 +CC(NCC(=O)Nc1ccc(N2CCCCC2)nc1)c1ccncc1 +CC(=O)c1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1C +CC1CN(Cc2nnc(-c3ccccc3)o2)CCO1 +CCC1CN(CC(=O)OC(C)C)c2cc(N)ccc2O1 +CC(NC(=O)CNC(=O)C1CCCC1)c1ccccc1 +Nc1c(Cl)ccn2c(Cc3ccccc3)nnc12 +CC(C)(CO)n1c(CC(F)(F)F)nc2cccnc21 +C=C(C)COc1cccc(C(=O)NC(C)c2nncn2C)c1 +O=C(CCCC(=O)c1ccc(F)cc1)NCc1ccccc1 +O=C(CNc1cccc(Cl)c1)NCc1cccnc1-n1cccn1 +Cc1cc(C#N)c(=O)[nH]c1-c1ccc2c(c1)CCC2 +CC(C)(CNC(=O)Nc1ccc(F)cc1OCC#N)c1ccncc1 +O=c1sc(-c2ccccc2)cn1Cc1nccn1C(F)F +Cc1ccc(-c2nc(CCN(C)C(=O)c3ccccc3)no2)cc1 +O=C(CCc1cccc(Cl)c1)OCCn1nc2ccccn2c1=O +CC(C)c1nn(C)cc1CNCCc1cccc2cccnc12 +O=C(NCCCNC(=O)C1CCCN1C(=O)C1CC1)c1ccccc1 +CC(C)CS(=O)(=O)NCC1(c2cccs2)CC1 +CC(C)(C)c1cc2ncc3c(n2n1)CC1CCC3N1Cc1ccoc1 +O=C(Cc1ccncc1)N1CCOCC(CO)C1 +CCc1ccc(-c2c(C#N)c(N)n(N)c(=O)c2C#N)cc1 +CC1COC2(CCN(C(=O)CSc3ccccc3)CC2)O1 +O=C(c1cc(F)cc(F)c1)N1CCC(OCc2ccccc2)CC1 +Cc1cc(CN(C)C(=O)Nc2cccc(C#N)c2)no1 +OCC1CN(C2CC2)C(c2c(F)cccc2Cl)O1 +Cc1cc(O)c2c(c1)C(c1cc(=O)cc[nH]1)NCC2 +CCOc1ccccc1Cn1c(=O)oc(=O)c2ccccc21 +CCn1c(=O)c2c(nc3n2CCN3c2ccc(Cl)cc2)n(C)c1=O +CCC(=O)NCC(C)(OC)c1cccc(Cl)c1 +C=CCCOC(C)C(=O)Nc1ccc(Cl)c(C(N)=O)c1 +O=C(Nc1ccccc1F)NC1CCN(C(=O)c2cnccn2)CC1 +Cc1cccc(-c2nc(CC(=O)Nc3cc(C)n[nH]3)cs2)c1 +CNS(=O)(=O)CC1CCCN1C(=O)C1CC1c1ccco1 +COc1ccc(-c2nnc(COc3ccccc3OC)o2)cc1 +N#Cc1cccc(C(=O)N2CCC3C2CCC(=O)N3c2ccccc2)c1 +Cc1cc(C)c(OCc2nc3c([nH]2)CCCNC3=O)c(C)c1 +CC(Nc1ccn(C)n1)C(=O)Nc1ccc(Cl)c(Cl)c1 +O=C(Nc1nncs1)C1CC(=O)N(c2ccccc2F)C1 +O=C(Nc1ccc(F)c(F)c1F)c1cccnc1OCC(F)F +COC(=O)c1ccc(S(=O)(=O)NCc2nc(C)c(C)o2)o1 +Cc1oc2ncn(C)c(=O)c2c1C(=O)Nc1ccc2c(c1)CCC2 +CC(C)(C)C(=O)N1CCCC(C(=O)NCc2ccco2)C1 +CS(=O)(=O)NCc1noc2c1CN(C(=O)c1ccco1)CC2 +O=C1Nc2ccccc2OC1CC(=O)N1CCc2ccccc2C1 +COc1ccc2nnc(CCCC(=O)Nc3nnc(C)s3)n2n1 +Nc1nccnc1C(=O)Nc1cccc(N2CCOC2=O)c1 +O=C(c1ccco1)N1CCCC(c2nc(-c3cccnc3)no2)C1 +NC(=O)c1cccc(NCC(=O)N2CCCCCC2)c1 +CC(C)(C)CC(=O)Nc1ccc(C(N)=O)c(N2CCCCC2)c1 +NC(=O)c1ncc(Br)c2cc(F)cc(F)c12 +Cc1cc(CNc2ccc(-n3cccn3)c(F)c2)no1 +CCOc1ccc(-c2cc(C)nc3[nH]nc(N)c23)cc1 +O=C(NC1CCCC1)C1COC2CCN(c3ncccn3)CC2C1 +CCn1ccnc1N1CCN(C(=O)c2ccccc2SC)CC1 +CSc1n[nH]c2ncnc(NCCn3nc(C)cc3C)c12 +CC(=O)Nc1cc(C(=O)N(C)C2CCCC2)ccc1F +O=C(COc1ccc(-c2ccccc2)cc1)N1CCOCC1 +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)NCc1ccco1 +CN(C)c1ccc(-c2nnn(CC(=O)OC3CCCCC3)n2)cc1 +CCC(Sc1nc(C)nc(C)c1C#N)C(=O)Nc1cc(C)on1 +N#Cc1ccc(-c2cnc(Cn3c4c(sc3=O)CCCC4)o2)cc1 +COCc1cccc(NC(=O)N(C2CC2)C(C)C2CC2)c1 +Cc1ccc(CNC2C(=O)Nc3cccc(Br)c32)cc1 +COc1ccc(CCC(=O)N2CCN(c3cnccn3)CC2)cc1 +Nc1ccc(NCCCCNC(=O)c2cccnc2)nc1 +Cc1cccc(NC(=O)C2CC(=O)N(C(C)C)C2)c1C(N)=O +O=C(Nc1cc(N2CCCC2)ncn1)c1cc2ccccc2o1 +COc1cccc(-n2cc(-c3ccc4c(c3)OCO4)[nH]c2=O)c1 +CCc1cc(NC(CC)c2ccnn2C)nc(N2CCOCC2)n1 +Cc1sc(NC(=O)C(O)c2ccccc2)nc1-c1ccc(F)cc1 +CCc1nc2n(n1)CCCC2NC(=O)c1cc2cccc(F)c2o1 +CC1CN(C(=O)CSc2nnc(C(C)(C)C)o2)CC(C)O1 +CCc1ccc(C(=O)NCC(=O)Nc2c(C)cc(C)cc2C)s1 +Cc1ncc(-c2ccc(S(=O)(=O)Nc3ccc(F)cc3)cc2)o1 +COC(=O)CC(C)C(=O)c1ccc(OC)c(C(C)C)c1 +CCOC(=O)CCC(=O)Nc1ccc(-c2nccs2)cc1 +CCC(C)Oc1ccc(NC(=O)C2CCCN2C(=O)C2CC2)cc1 +Cc1ccc(NC(=O)C2CC=CCC2C(=O)N(C)C)cc1 +CC(=O)Nc1cccc(COC(=O)c2cnc3ccc(C)cn23)c1 +O=c1c2ccccc2n2c(=O)[nH]nc2n1CCc1ccccc1 +O=S(=O)(c1ccccc1)N1CCCC1c1nc2ccccc2[nH]1 +O=C(c1cnc(N2CCCCC2)nc1)n1ccnc1 +CC1Cc2cc(C(=O)Nc3ccc4c(c3)OCCCO4)ccc2O1 +O=C(CN1CCN(c2ncc(Cl)cc2F)CC1)N1CCCC1 +Cc1nc2sc(=Cc3ccc(Cl)c(Cl)c3)c(=O)n2n1 +CCOc1ccc(NC(=O)c2cccc(NC(=O)CC)c2)cc1 +CCCNc1nnc(-c2cc(C(C)C)nn(CC)c2=O)s1 +CC(=O)N1CCc2ccc(S(=O)(=O)N3CCCCCC3)cc2C1 +Cc1ccc(NC(=O)N(C)C)c(C(=O)NC(C)CCC(C)C)c1 +Nc1ccc(S(=O)(=O)Nc2cnn(-c3ccccc3)n2)cc1 +O=C(NCCCn1cnc2ccccc21)NCc1ccccc1F +C=CCCCN(C)C(=O)c1cc(C2CC2)nc2c1c(C)nn2C +Cc1nnc(NC(=O)c2csc(-c3cnccn3)n2)s1 +Cc1cc(CNC(=O)Cn2cccc(C(F)(F)F)c2=O)c(C)o1 +CC(C)(C)OC(=O)N1CCCC1C(=O)CCc1ccccc1 +CC(C#N)CN(C)C(=O)C1COc2ccc(Cl)cc2C1 +Cc1csc(N2CCCN(C(=O)C3Cc4ccccc4O3)CC2)n1 +CC(C)CN(CC(C)C)C(=O)C1CCN(c2ncccn2)CC1 +Cc1csc(CN2CCN(C(=O)OCC(C)C)CC2)n1 +c1ccc(C2Nn3c(nnc3-c3cccnc3)S2)cc1 +Cn1cc(CCNS(=O)(=O)CC2CCCCC2)cn1 +Cc1c(-c2ccc(C(N)=O)c(Cl)c2)c(C(F)(F)F)nn1C +CCOc1ncccc1CNC(=O)c1ccc2c(c1)OCC(=O)N2 +Nc1ccc(S(=O)(=O)Nc2ccc(Cl)cc2)cc1 +O=C(Cc1cccc(O)c1)Nc1cccc2[nH]cnc12 +CC(=O)N1CCC(C(=O)Nc2ccc(NC(=O)NC(C)C)cc2)CC1 +CC1COCCN1CC(=O)Nc1sccc1C#N +Cc1ccc(-c2cc(C(=O)NCCCO)on2)cc1 +COc1cccc(NC(=O)NCc2ccc(C)cc2)c1 +CC(C)OCC(=O)NCc1ccnc(-n2ccnc2)c1 +CCCn1nc(C(=O)Nc2ccc(Cn3ccnc3)cc2)ccc1=O +c1csc(Cc2noc(CCc3cn[nH]c3)n2)c1 +CC(C)CN(CC(C)C)C(=O)CCn1ncc(=O)c2ccccc21 +N#Cc1ccccc1NC(=O)CCc1ccccc1N +CCOCCNC(=O)c1ccc(F)c(NC(C)=O)c1 +Cc1cccc(C)c1NC(=O)NCCc1ccn(-c2ccccc2)n1 +CC(C)CN(CC(C)C)C(=O)c1cc(F)ccc1F +C=CCCOC(C)C(=O)Nc1ccc(=O)n(CC)c1 +CCCn1cc(CCNC(=O)c2ccnn2CC)c2cccnc21 +Cc1noc(C)c1C1CCCN1C(=O)c1cc(C2CCCCC2)no1 +Nc1cccc(OCc2nc(-c3ccccc3)cs2)c1 +CN(CCc1ccccn1)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +COCCN1CCN(C(=O)c2cccc(CCC(C)(C)O)c2)CC1 +COc1ccc(NC(=O)CCCNC(=O)c2ccco2)cc1C +CCN(CC(F)(F)F)C(=O)Cn1cccc(OC)c1=O +O=S(=O)(NC1CCCC1O)c1ccc(F)cc1 +Cc1cc(CN(C)S(=O)(=O)c2cc(Cl)cc3c2OCC3)no1 +CC(c1nnc(-c2cccs2)o1)n1nc(-c2ccco2)oc1=O +COc1cc(C#N)ccc1OCC(=O)NCCC1CC2CCC1C2 +C#CCOc1ccc(N(C)C(=O)c2ccncc2F)cc1 +Cn1ncnc1CNC(=O)Cc1ccc(F)cc1F +O=C(c1ccncc1)N1CCC(Oc2nncc3ccccc23)CC1 +CN(C)C(=O)Cc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1 +CC(C)CCNc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 +CCN1C(=O)C(C)(C(=O)NCc2ccncc2)Oc2ccccc21 +Cc1cc(NC(=O)C2CC(=O)Nc3cc(F)ccc32)c2ncccc2c1 +CC(=O)c1cccc(OCC(=O)NCCN2CCOCC2)c1 +COCCN(C)C(=O)c1cccc(NC(=O)c2ccco2)c1 +CN1CCN(C(=O)C2CC23C(=O)N(C)c2ccccc23)CC1 +CN(C)c1nccc(NC(=O)C2CCC(F)(F)CC2)n1 +Cc1ccc(C)c(C(=O)N2CCCN(C(=O)OC(C)(C)C)CC2)c1 +Cc1cc(-c2c[nH]nc2C2CCCCN2C(=O)C2CCCC2)on1 +Cc1nc(C)c(C(=O)NCc2c[nH]nc2C)s1 +CCOC(=O)c1cnn(C(=O)c2ccccc2)c1N +CCOC(=O)c1cc(C(=O)Nc2ccc(C(C)=O)cc2)c(=O)[nH]c1C +COc1ccccc1-c1cc(NC(=O)c2occc2C)[nH]n1 +COC(C)C(=O)Nc1ccc(C)cc1OCC1CCCO1 +O=C(CCc1cccc(Br)c1)NCc1ccco1 +CCCn1nc(C(=O)NC(C)c2cccs2)ccc1=O +Cc1nc2c(cnn2C(C)C)cc1C(=O)Nc1ncc(C(N)=O)s1 +CC(=O)Nc1cccc(OC(=O)C(CC(C)C)N2CCCCC2=O)c1 +CCCC1CN(C(=O)Nc2cccc(C(=O)NC3CC3)c2)CCO1 +CC(NC(=O)Nc1ccc(OCC2CCCCC2)cc1)c1nc[nH]n1 +Cc1[nH]ncc1C(=O)N1CCCN(C(=O)CCc2ccccc2)CC1 +COc1c(F)cc(NC(=O)c2ccn(-c3ccccc3)n2)cc1F +CC(C)CCNC(=O)Nc1ccccc1CN1CC(C)OC(C)C1 +CCC(C)Oc1ccc(NC(=O)NCCc2cccnc2)cc1 +CCn1cc(NC(=O)c2nnn(-c3ccc(F)cc3)c2C2CC2)cn1 +CNC(=O)CNc1cc(C(F)(F)F)ccc1Cl +CCCn1c(=O)sc2cc(NC(=O)C3CC3)ccc21 +CCc1ccc(NC(=O)C2CCN(C(=O)NC3CC3)CC2)cc1 +Nc1nc2c(cc1C(=O)Nc1c(F)cccc1F)CCC2 +Cc1cc(C)c2nc(C3CC3)cc(C(=O)N(C)Cc3cnccn3)c2c1 +COc1cc(C(O)c2cccs2)c(OC)cc1Cl +O=C(CN(C(=O)c1csnn1)C1CC1)NC1CCCCC1 +NC(=O)c1c(O)cc(Br)c(O)c1Br +COc1ccc(C(O)Cn2cnc3cc(F)c(F)cc32)cc1F +CN(C(=O)c1ccc(N2CCCC2=O)cc1)c1ccccc1F +CCCCN(CCO)C(=O)c1sc2ncn(C)c(=O)c2c1C +COc1ccc(Br)c(C(=O)OCC(=O)NC2CC2)c1 +COc1cc(C(=O)NC2CC2)ccc1OCc1cscn1 +O=C(NCCc1ccc(F)cc1)C1CCCN1C(=O)c1cccs1 +Cc1ccccc1CNS(=O)(=O)c1cn(C)nc1N +CCCCN1C(C)=NS(=O)(=O)c2cc(C(=O)NC3CC3)ccc21 +CCOc1ccccc1CNC(=O)CNC(=O)c1cccs1 +CNC(=O)c1cc(S(=O)(=O)Nc2cccc(C)c2)ccc1OC +Cc1cccc(CNC(=O)c2nn3ccccc3c2Cl)c1 +O=C(OC1CCCCC1=O)c1cc2ccccc2[nH]1 +O=C(Nc1ccc2nc(C3CC3)[nH]c2c1)c1ccco1 +CC(=O)Nc1cnc2c(C(=O)NCc3ccco3)cccn2c1=O +O=C(NCC1CCCCC1)c1cc2n(n1)Cc1ccccc1NC2=O +CCCNC(=O)CCc1c(C)nc2cc(C)nn2c1C +CC(=O)c1ccc(C(=O)OCc2cc(=O)oc3cc(O)ccc23)s1 +Cc1ccc(S(=O)C(C)C(=O)Nc2ccc(F)cc2F)nc1 +CCS(=O)(=O)N1CCCC(C(=O)Nc2ccc(F)c(F)c2)C1 +O=C(c1ccsc1)N1CCN(C(=O)c2cnn3ccccc23)CC1 +CN(CCOCC1CC1)Cc1nc(N)c2c3c(sc2n1)CCCC3 +O=C(NC1CC(=O)N(Cc2ccccc2Cl)C1)c1ccncc1 +O=C(CNC(=O)c1ccc2c(c1)OCO2)Nc1ccccc1F +Cc1nn(C)c(C)c1CNC(=O)CCn1ncc2cc(Cl)ccc21 +Cc1ccc(N(C(C)C(N)=O)S(C)(=O)=O)cc1C +O=C(CC1CCCC1)N1CCC(OCc2ccc(F)cc2)CC1 +O=C(NCCc1c(Cl)cccc1Cl)NCc1ccco1 +COc1ccnc(NC(=O)CCc2cnn(-c3ccccc3)c2)c1 +CC(=O)NC(C)C(=O)OC(C)C(=O)N1CC(=O)Nc2ccccc21 +COCCN1C(=O)CCc2cc(NC(=O)c3cccc(C#N)c3)ccc21 +Cc1cc(C(=O)CN2CCOC(C)C2)ccc1F +COc1cccc(C(=O)N2CCC(c3ccsc3)CC2)c1 +CCNS(=O)(=O)c1cnn(-c2ccccn2)c1 +O=C(c1cscn1)N1CC(OCC2CC2)C2OCCCC21 +COc1ccc(CC(=O)N2CCCC2C(=O)NCc2ccco2)cc1 +Cc1ccc(C(=O)NC(C)C(=O)N2CCCC2)cc1F +Clc1ccc(OCc2n[nH]c(-c3ccncc3)n2)cc1 +CCOC(=O)c1ccc(N2CC(C(=O)OCC)CC2=O)c(C)c1 +O=C(OCc1cc(-c2ccccc2)no1)c1cnn2cccnc12 +COCC(=O)NC(Cc1ccsc1)c1nc(C)cs1 +N#Cc1ccccc1OCC(=O)OCC(=O)C1=NC=CC1 +Cc1c(C(=O)N(C)C)oc2ccc(Br)cc12 +Cc1n[nH]c(C)c1NC(=O)c1cnn(Cc2ccccc2)c1 +CC(C)NC1=NS(=O)(=O)c2cc(Cl)ccc2N1 +Cc1ccc2oc(C(=O)N3CCCCC3Cn3cccn3)cc2n1 +CN(C)c1nc2sc(C(=O)NC3CCCCNC3=O)cc2s1 +Cc1ccc2c(c1)N(C(=O)c1[nH]c(C)c(S(N)(=O)=O)c1C)CCC2 +CN(CC(O)CN1CCOCC1)C1CCCN(c2ccccc2)C1 +CC(C)C(=O)Nc1ccc(NC(=O)C2CCC2)cc1 +O=C(CSc1nnc(-c2cccs2)o1)N1CCOCC1 +O=C1OCCN1c1cccc(NC(=O)N2CCCOC3CCCC32)c1 +COc1ccc(CCNc2c(C#N)cnc3ccccc23)cc1OC +Cc1noc(C2CC3CN(C(=O)c4ccsc4)CC3O2)n1 +CCNC(=O)c1cc2c([nH]c1=O)CC(C)(C)CC2=O +COc1ccc(CNC(=O)c2ccc(C)nc2C)cc1F +CC(C)C(C)(C#N)NC(=O)CN1CCN(C(=O)C2CC2)CC1 +CCCC(C(=O)Nc1nc(CC(N)=O)cs1)c1ccccc1 +CS(=O)(=O)N1CCCC(S(=O)(=O)N2CCc3ccccc32)C1 +CCc1nnc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)s1 +Cc1cc(C(F)(F)F)nc(CCNc2nnc(C)o2)n1 +Cc1ccn2ncc(C(=O)N3CCCN(c4cccnn4)CC3)c2n1 +COC(=O)Nc1ccc(OC(=O)c2cnn(C)c2-n2cccc2)cc1 +COc1cccc(-c2nnc(SCC(=O)Nc3ncccn3)o2)c1 +CCCn1cc(C(=O)NC(C)c2c(C)nn(CC)c2C)c(C)n1 +COc1ccc(C(C)(C)CNC(=O)NCc2ncn(C)n2)cc1OC +COc1cc(OC)c(C(=O)NCC(C)C)cc1OC +O=C(NCC1CCN(C(=O)Oc2ccccc2)CC1)c1ccccc1 +CC(NS(=O)(=O)c1cccc(C#N)c1)c1ccccn1 +Cc1ccc(OC(=O)CCNC(=O)OC(C)(C)C)c(C)c1 +COc1ccc(C)cc1NC(=O)Cn1cc(CO)nn1 +O=C(NCCCn1ccc2cccnc21)c1cccs1 +COc1ccc(NC(=O)Cc2nnc(-c3ccsc3)o2)c(OC)c1 +O=C(NCc1ccc(F)cc1)Nc1cccc(N2CCCC2=O)c1 +CCOc1ccc(C(=O)COc2ccc(-c3nnco3)cc2)cc1 +O=C(NC1CCCc2ccccc21)c1cc(CN2CCOCC2)on1 +CCOc1ncccc1CNC(=O)c1cccc(OC)c1F +CCc1nn(CC(=O)N2CCC3(CC2)OCCO3)c(=O)c2cccn12 +COc1ccc(NC(=O)c2sccc2C)cc1OC(F)F +O=C(Cc1ccccc1)NCc1ccc(-c2nc3ncccc3o2)cc1 +CC(=O)N1CCN(CCNC(=O)NCc2sccc2C)CC1 +CCC(C)NC(=O)CCNC(=O)Nc1ccc(-c2csnn2)cc1 +COC(=O)c1ccc(C(=O)Nc2n[nH]c(-c3ccoc3)n2)cc1 +Cc1cc(=O)c(C(=O)Nc2cccnc2)nn1-c1ccccc1 +CC(OC(=O)c1nccnc1N)C(=O)Nc1ccc2c(c1)OCCO2 +Cc1ccc(C(C)NC(=O)NCCNC(=O)OC(C)(C)C)cc1F +CCc1ccc(C(C)NC(=O)C(C)Sc2nncn2C2CC2)cc1 +CCC(C)NC(=O)Cn1nnc2cc3c(cc2c1=O)OCCO3 +CC(=O)c1ccc(NC(=O)CCc2nc3ccccc3s2)cc1 +CCCS(=O)(=O)N1CCC2C1CCC(=O)N2Cc1ccncc1 +Cc1nc2ccc(C(=O)N(CCC#N)Cc3cccnc3)cc2nc1C +Cc1ccc2ncc(C(=O)NC(C)C3CCCO3)n2c1 +COCCN1C(=O)C(=O)c2c(Br)cccc21 +CCOc1c(O)c(Cl)cc2c1C(CC(C)C)NCC2 +Cc1nc2cc3c(cc2n1-c1ccccc1N)OCCO3 +Fc1ccc(-c2nc(CN3CCOCC3C3CC3)co2)cc1F +CC(NC(=O)NC1CCCCCC1)c1cccc(S(N)(=O)=O)c1 +CCOC(=O)C(Cc1nc(-c2ccncc2)cs1)NC +CCOC(=O)C1=Nn2c(nnc2-c2ccccc2)SC1 +COC(=O)c1ccc(Cn2nnnc2C(C)(C)C)cc1F +COCCN(CC(C)C)C(=O)Nc1ccccc1S(C)(=O)=O +CCCCC1C(=O)N(C)CCN1C(=O)c1cc(C)n(CC)c1C +N#CCC(C1CCCC1)n1cc(-c2ncnc3[nH]ccc23)cn1 +Cc1cc2occ(CC(=O)NCC(C)n3cncn3)c2cc1C +CC1(C)CNc2ccccc2N1Cc1cccnc1 +Cc1ccccc1C1CC(C)N(C(=O)c2ccc(-n3ccnn3)cc2)C1 +O=C(Nc1cc(-n2ccnc2)ncn1)c1ccncc1 +CN(CC(F)(F)F)C(=O)COc1ccc(F)c(Cl)c1 +O=C(NCc1cc(F)ccc1Br)NC1CCC(O)CC1 +CCCC(=O)N1CCCC1C(=O)c1cc(C)ccc1OC +CC(O)c1ccc2c(c1)C(NC(=O)C1CC1)CC(C)(C)O2 +CCc1ccc(CNC(=O)c2sc(C(C)C)nc2C)s1 +COCCN1CCn2c(nc3cc(C(N)=O)ccc32)C1 +N#Cc1ccc(OCCOC(=O)c2cnc(C3CCCO3)s2)cc1 +C=CCNC(=O)c1ccc(OCc2ccccc2)cc1 +Fc1ccc(NCc2nnc(C3CC3)o2)c(-c2ccc(Cl)cc2)c1 +Cc1cc(NC(=O)C(c2ccccc2)n2cccc2)no1 +CN(CC(=O)NCCO)S(=O)(=O)c1ccc(Cl)cc1 +O=C(CN1C(=O)COc2ccc(Cl)cc21)NCc1ccccn1 +Cc1cccc(C(=O)N2CCOCC2C2CC2)c1O +N#Cc1ccc(OCCCN2CCOCC2C2CC2)cc1 +CCC(=O)Nc1cccc(NC(=O)c2cccc3[nH]ccc23)c1 +COc1ccccc1OCC(=O)N(C)Cc1cccc(Cl)c1 +CC1CC(C)CN(C(=O)CN2CCN(c3cccc(Cl)c3)C2=O)C1 +C=CCN(Cc1ccccc1)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +COc1ccc(NC(=O)NCCc2c(F)cccc2F)cn1 +CCCNS(=O)(=O)c1ccc2c(c1)CC(C)N2 +Cc1csc(NC(=O)CSc2nnc(C)n2-c2ccccc2)n1 +O=C(NCc1cc(=O)n(-c2ccccc2)[nH]1)c1ccc2ccccc2c1 +CC(=O)C(C)n1c(CNC(=O)c2ccccc2F)nc2ccccc21 +CSc1ncnc(NCC(=O)NC(C)C)c1C#N +CCCN1C(=O)NC(c2ccncc2)C(C(=O)OC)=C1CC +CC(=O)N(C)c1ccc(NCC(=O)Nc2ccccc2Cl)cc1 +CCN(CC1CC1)C(=O)Nc1ccc2oc(C3CC3)nc2c1 +Nc1cc(S(=O)(=O)N2CCOCC2)ccc1OCC(F)(F)F +O=C(c1cn2cccnc2n1)N1CC2(CCCC2)c2c(F)cccc21 +CC1CC1C(=O)N1CCC(C(=O)N2CCC(C(N)=O)CC2)CC1 +Cc1ccccc1NC(=O)Cn1c(C)cc(C)c(C(N)=O)c1=O +CSc1nc2nnc(-c3ccccc3)c(N)n2n1 +Brc1ccc2nnc(C3CCOCC3)n2c1 +COc1cc(F)ccc1NC(=O)Nc1ccc(S(N)(=O)=O)cc1 +c1coc(-c2nnc(CN3CCc4ccccc4C3)o2)c1 +COC(=O)c1cc(-c2ccc3c(c2)CC(=O)N3)nn1C +CCNc1ccc(C(=O)OCC)cc1NC(=O)C1CC1C +CCCn1cc(S(=O)(=O)NC(C)CO)c(N)n1 +Cc1cc(Cl)cc(C)c1CN(C)C(C)CC#N +CCN(CC)S(=O)(=O)CCNC(=O)NC1CCCC1 +CS(=O)(=O)NCC(Cc1cccc(F)c1)N1CCCC1=O +O=C(CSc1ccccn1)Nc1ccc(Br)cc1F +CCC(C)C(=O)c1cc2c(cc1Cl)OCCO2 +CCCc1nnc(SCC(=O)Nc2ccc(Cl)cc2)n1N +CC(=O)c1cc(CCC(=O)N2CCCCCC2)oc1C +O=C(CNS(=O)(=O)CC1CCOC1)Nc1cccc(F)c1 +Cc1ccccc1CNC(=O)c1c(C)noc1-c1cccnc1 +Cc1cccc2c1CCN(c1cc(N3CCCC3CO)ncn1)C2 +Cc1ccc(C)c(OCCCN(C)C(=O)c2cnc(C)[nH]c2=O)c1 +CCOC(=O)C1CC(=O)N(c2ccc(-c3ccccc3)cc2)C1 +CCCCOCCS(=O)c1c(F)cc(N)cc1F +CCOc1ccccc1Nc1ncccc1C(N)=O +CC(Oc1ccc(O)cc1)C(=O)N(C)c1ccccc1F +Brc1ccccc1CN1CCN(c2ncccn2)CC1 +O=C(c1sccc1Br)N1CCC(O)(C(F)(F)F)C1 +CCc1ccc(C(NS(C)(=O)=O)C(C)C)cc1 +COC(=O)N1CCN(C(=O)Nc2nc(C)c(C)s2)CC1 +Cc1ccc(C)c(OCc2c(C#N)nnn2CCO)c1 +COCCSc1ccccc1C(=O)Nc1c(C)cccc1C +CN(C)C(=O)N1CCN(C(=O)Nc2ccccc2F)CC1 +CN(CCc1ccccc1)C(=O)c1cc2ccccc2c(=O)[nH]1 +O=C(Nc1ccc(S(=O)(=O)N2CCOCC2)cc1)c1ccco1 +COc1ccccc1-c1nnc2n(C)c3ccc(N)cc3n12 +COc1cc(C)ccc1NCC(=O)Nc1cccc(C(C)=O)c1 +COc1ccc(NC(=O)C(C)n2nnc3ccccc3c2=O)cc1 +O=C(Cc1ccc(F)cc1F)Nc1cccc(-c2nc[nH]n2)c1 +O=C(NC1CCc2cc(F)ccc21)c1n[nH]c(=O)c2ccccc12 +O=C1CC(c2ccc(Cl)cc2)c2cc3c(cc2N1)OCCO3 +O=C(Cc1ccccc1)NCC(O)c1ccc2c(c1)CCCC2 +CCc1c(CO)nnn1-c1cc(Cl)cc(Cl)c1 +CC(C)(C)CCCC(=O)NCC(O)c1c(F)cccc1F +CCn1c(CCCNC(=O)C(C)C)nc2ccccc21 +O=C1COc2ccc(NS(=O)(=O)c3cc(F)cc(F)c3)cc2N1 +CCOC(=O)C1=C(C)N(C)C(=O)N(C)C1c1cccs1 +CCOc1ccc(C(=O)N(C)c2ccc(F)cc2)cn1 +O=C(Nc1ccccc1-n1cnnn1)c1cc2ccccc2o1 +CC(Sc1nnnn1C1CC1)C(=O)OCc1nccs1 +Nc1ccc(C(=O)Nc2ccc3c(c2)OCO3)c(Cl)c1 +CCOc1cccc(CN2CCCC(CN3CCOCC3)C2)c1 +COc1cc(-c2nc3ccc(C#N)cn3n2)ccc1O +CC(C)c1c(C(=O)N2CCCC2)c(C2CC2)nn1-c1ccccc1 +CCn1c(SC(C)C(=O)N(C)C)nnc1-c1ccncc1 +CS(=O)(=O)N=c1[nH]ccc(OC2CC2)c1C(F)(F)F +CCn1c(CN(C)C(=O)Nc2cccc(C#N)c2)nc2ccccc21 +CCCOc1nc(CC(C)C)nc(NCC)c1N +Cc1ccc(C2OCCCC2NC(=O)Cn2cnnn2)cc1 +CC(Sc1nnc(NC2CC2)s1)C(=O)NC1CC1 +CCOC(=O)c1ccc(CN2CC(C)OC(c3ccc(F)cc3)C2)o1 +CCCCS(=O)(=O)Nc1ncn(Cc2ccc(F)cc2)n1 +CCC(C)NC(=O)c1cnn(-c2ccc(F)cc2)n1 +O=C(CCOc1ccccc1F)NCc1ccncc1 +CC(=O)N1CCc2ccc(C(=O)N3CCCCCC3)cc21 +Cc1cc(C(=O)N(C)Cc2ccc3c(c2)OCCO3)c(C)o1 +CCCOCc1ccccc1CNC(=O)C1CC=CCC1 +CCn1c(=O)c(O)nc2c(=O)oc3ccccc3c21 +c1csc(CCNCc2cccc3cccnc23)c1 +Cc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)CC(C)(C)C +CSc1ccccc1C(=O)Nc1cccc(C#N)c1 +CC(=O)Nc1ccc(NC(=O)Cc2cccc(F)c2)cc1 +CC1CCN(C(=O)CCc2ccc3c(c2)OCO3)CC1 +CCOC(=O)CC(C)CNC(=O)N1CCCC(C)CC1 +O=C(NCC1CC=CCC1)Nc1nnc(-c2ccsc2)s1 +CCCCCC(C)NC(=O)c1ccc(-n2cncn2)nc1 +CC(=O)N1CCN(c2c(Cl)cccc2NC(=O)CC(C)C)CC1 +CC(NC(=O)COc1cccc(C(=O)NC2CC2)c1)c1cccs1 +O=C(COc1ccc(Br)cc1)Nc1nccs1 +CCCOC1CCCN(C(=O)NCc2c(C)cc(C)[nH]c2=O)C1 +Nc1nonc1CC(=O)Nc1ccc2c(c1)OCO2 +COc1cccc(NC(=O)C(C)Sc2nnc(-c3ccco3)o2)c1 +O=C1CN(Cc2c[nH]nc2-c2cccnc2)C2CCCCC2N1 +CCN(Cc1cccc(NC(=O)c2ccc(O)c(Cl)c2)c1)C(C)=O +CCc1ccc(C(=O)OCC(=O)NCC2CCCO2)cc1 +COc1ccc(CCNC(=O)c2ccc(OC)cc2)cc1 +CC(=O)N1CCc2ccccc2C1CC(=O)N1CCOCC1C1CC1 +COC(=O)C(NCc1ccccc1F)C(C)(C)C +Cc1ccn2c(=O)cc(COc3nnc4ccccn34)nc2c1 +Cc1nnc(COC(=O)C2c3ccccc3Oc3ccccc32)o1 +Cc1nc(C(=O)Nc2nnc(C(C)(C)C)s2)cs1 +CC(C)CC(C)OCC(=O)Nc1ccc(F)cc1N +Cc1ccc(F)c2c1CCCN2C(=O)Cc1c(C)nn(C)c1C +Cn1cc(C(=O)NC2CCCCC2)c(=O)c2ccccc21 +CC(=O)N1Cc2ccc(C(O)c3ccccc3F)cc2C1 +O=C(CCNC(=O)NC1CCN(c2ccccc2)C1)NC1CCCC1 +CN(CC(=O)NC1CCCC1)C(=O)c1c[nH]c2ccccc12 +COCC(O)CN(C)c1nc(C2CCCC2)nc2c1cnn2C +CC(C)C1Oc2cc(N)ccc2N(CC(N)=O)C1=O +Cc1cc(C)n(CCCC(=O)N2CC3CCN(C(=O)N(C)C)C3C2)n1 +C#CCN1CCN(CC(=O)NCCSc2ccc(C)cc2)CC1 +COCCCNS(=O)(=O)c1cccc2cccc(Cl)c12 +Cc1cnn(CCC(=O)Nc2cnn(CC3CCCO3)c2)c1 +CC(NC(=O)Nc1nnc(C(F)F)s1)C(=O)NC(C)(C)C +CCC1C2CCCCN3C(=O)CC(C4C(C)C(=O)OC14)C23 +COc1ccc(-c2cc(=O)c3cc(F)ccc3o2)cc1OC +CC(CO)(NC(=O)NCc1nc2ccccc2s1)C1CCCCC1 +COc1cc(C(=O)Nc2cc(F)cc(F)c2)ccc1OCC(N)=O +O=C(Cc1cccs1)NCc1ccc(Cn2cc(Cl)cn2)cc1 +COc1ccccc1OCC(=O)N1CC(C)C(O)(C2CC2)C1 +CNc1cc(COc2ccc3c(c2)OCO3)ccn1 +CC(C)C(NC(=O)c1ccco1)C(=O)NCCc1cccc(Cl)c1 +COc1ccc(C2(C)Nc3ccccc3C(=O)N2C(C)C)cc1 +CC(NC(N)=O)C(=O)NCCOc1cccc(Br)c1 +NC(=O)Nc1cccc(Cl)c1SCC(F)F +COc1ccc(CN2C(=O)Cc3cc(N)ccc32)c(OC)c1 +NC(=O)c1ccc(NC(=O)c2cc(F)c(Cl)cc2Cl)cc1 +Cc1ccc(C)c(NC(=O)Cc2nc(COC(=O)C3CC3)cs2)c1 +Cn1ccsc1=NC(=O)C1(C)CC1(Cl)Cl +Cc1ccc2nc(CN(C)C(=O)c3cc(C(C)C)nn3C)[nH]c2c1 +CC1CN(C(=O)Cc2ccc[nH]2)CCN1C(=O)OC(C)(C)C +CC(c1ccco1)N(C)S(=O)(=O)N1CCCCCC1 +CCN1CC(C(=O)Nc2cc(S(C)(=O)=O)ccc2Cl)CC1=O +Cc1ccc(CN2CCC(c3nnc(-c4ccncc4)o3)C2)o1 +CC1CN(C(=O)Nc2ccc(OC(F)F)cc2)CC(C)O1 +CC(=O)Nc1cc(NCC(=O)N2C(C)CCCC2C)ccc1F +CCN(CCOc1ccccc1F)S(C)(=O)=O +CCC(C)NC(=O)C(C)n1nc(-c2ccccc2)ccc1=O +O=C(c1ccccc1)c1nn2c(nc(=O)c3ccccc32)s1 +COc1ccnc(N2CCN(C(=O)COc3cccnc3)CC2)n1 +CCOc1ccc(NC(=O)CN(C)S(C)(=O)=O)c(C)c1 +Cn1ccnc1SCCOc1ccc(S(N)(=O)=O)cc1 +O=C(CC1CC2CCC1C2)N1CCC(OCc2ccccc2)CC1 +CS(=O)(=O)N1CCN(C(=O)c2cccc(F)c2)CC1 +CCCCCCNC(=O)Cc1c(C)nc(C)[nH]c1=O +CCCC(=O)Nc1sc2c(c1C(=O)N1CCCCC1)CCCC2 +O=C(COc1ccc(-c2nnco2)cc1)NC1CCCC1 +COC(=O)c1ccc(C(=O)Nc2ccccc2F)nc1 +Cc1noc(C)c1C(C)NC(=O)c1cccc(NC(=O)NC(C)C)c1 +CC(Sc1cc(C#N)ccn1)C(=O)N(C(C)C)C(C)C +COC(=O)CCC(=O)Nc1ccccc1C(=O)NC(C)C +O=C(c1ccc(F)cc1)N1CCCC(C(F)(F)F)C1 +O=c1[nH]c2cc(NCc3ccccc3Br)ccc2o1 +CN(C)C(C(=O)N1CC(c2cccnc2)C1)c1cccc(F)c1 +CCC(C)C(=O)OCc1cc(=O)oc2cc(O)ccc12 +COC1(C)CC(NC(=O)Cc2cccc(OCC#N)c2)C1(C)C +CCCc1nnc(N2CCN(C3CCCC3)C(=O)C2)o1 +c1ccn2cc(CSc3ncnc4sccc34)nc2c1 +CC(=O)Nc1ccc(OC(=O)c2cc(C(N)=O)cs2)cc1 +O=C(CO)N1CCN(C(=O)c2ccc(Oc3ccccc3)o2)CC1 +CC(C)CCOC1CCCCC1NC(=O)C1CCOCC1 +Cn1cc(C(=O)N2CCCC2c2ccccn2)cn1 +CCOc1cc(CNS(C)(=O)=O)ccc1OC +C=CCNC(=O)c1cccc(S(=O)(=O)NC(C)c2ccccc2)c1 +CC(=O)Nc1ccc(Br)c(C(F)(F)F)c1 +CNC(=O)CC1CC2(CCN(C(=O)COC)CC2)c2ccccc21 +O=C(Cn1nc(-c2cccs2)ccc1=O)NCc1cccnc1 +CN1C(=O)C2CCC1CN(C(=O)c1cc(N)ccn1)C2 +CC(C)NC(=O)CN(C)C(=O)C(C)Sc1ccccc1 +Fc1cc(F)cc(NCc2ccc3c(c2)OCO3)c1 +Cc1cc(NC(=O)c2ccccc2Cl)ccc1-n1cnnn1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(C(F)(F)F)nc2)cc1 +Cc1nc(CCC(O)c2ccccc2Cl)sc1C +COc1ccc(F)c(NC(=O)C2CCCOC2)c1 +Cn1cc(CNC(=O)c2ccnc3ccccc23)cn1 +Cc1cc(C(=O)NC(c2cccs2)c2cccs2)on1 +Cc1nc[nH]c1-c1nccn1C1c2ccccc2-c2ccccc21 +Cc1ccc(NC(=O)N(C)C(CO)C(C)(C)C)cc1S(C)(=O)=O +CC1CCC(C)N1C(=O)c1cccc(-c2ccoc2)c1 +CCOC(=O)c1ccc(N2CCOCC2)c(NC(=O)C(C)(C)C)c1 +Cc1c(C(=O)NCc2ccccc2Cl)oc2ccc(F)cc12 +NC(=O)c1cccc(CNc2ccc(Cl)cc2Cl)c1 +COCCOCC(=O)Nc1sc2c(c1C(N)=O)CCCC2 +Cc1cc(C)n(Cc2cccc(C(=O)N3CCCCC3C)c2)n1 +C=CCCCN(C)S(=O)(=O)c1ccc(F)cc1C +Cc1ccccc1C(=O)N1CCN(CC(C)C#N)CC1 +C=CCNC(=O)Nc1ccccc1-n1cc(Br)cn1 +O=C(O)C1CN(c2ccc(Cl)c(Cl)c2)C1=O +COC(=O)c1sccc1S(=O)(=O)N1CCCCCC1 +Cn1c(C2CC2)nc2cc(NC(=O)C3CCC3)ccc21 +Nc1nc(N)nc(CSc2nnnn2-c2ccc(O)cc2)n1 +Nc1n[nH]c(N)c1Cc1cccc(Br)c1 +Cc1n[nH]cc1NC(=O)c1c(O)cccc1Cl +CCCC(=O)Nc1c2c(nn1-c1ccccc1)CCC2 +Cc1cccnc1NC(=O)CCc1c(C)nn(-c2ccccc2)c1C +CC(C)NS(=O)(=O)c1ccc(NC(=O)CC2CCCC2)cc1 +NC(c1nnc(C2CC2)o1)c1ccc(F)c(F)c1F +CN(Cc1ccc(F)cc1)C(=O)c1ccc(CCC(C)(C)O)cc1 +Fc1ccccc1C1(CNCc2cccnc2)CC1 +COCC(C)OC(=O)Cn1nnc2ccccc2c1=O +CN(C1CCCC1)S(=O)(=O)c1ccc(F)cc1 +Nc1ccc(C(=O)c2ccc3c(c2)CCCN3)cc1 +Cc1ccc(C(=O)NCCc2nncn2C)cc1Cl +Cn1cc(C(=O)Nc2cc(-c3cccs3)n[nH]2)c(C(F)(F)F)n1 +Cc1cccc(C(=O)Nc2ccc3c(c2)OCC(C)(C)C(=O)N3)c1 +COC(=O)c1cc(F)c(Br)cc1F +COC(=O)C1=C(NC(=O)Nc2ccc(OC)cc2)CCC1 +O=C(CCCc1cc(F)ccc1F)N1CCN(c2cnccn2)CC1 +Cc1cc(C(=O)NCCCN2CCCC2=O)[nH]n1 +O=C(NCCNC(=O)c1ccc2cnsc2c1)Nc1ccccc1 +C=CCN(Cc1ccccc1Cl)C(=O)c1cnn(CC)c1 +COC(=O)c1cc(OC)ccc1OCC(=O)N1CCOC(C)C1 +CN(CCCCNC(=O)c1cc[nH]n1)c1ccccc1 +COc1ccc(N)cc1CNc1ncccc1C(F)(F)F +COc1ccc(N)cc1Cn1ncc2ccccc21 +CC1=CCC2CN(C(=O)c3cnc(N4CCCCC4)nc3C)CC2C1 +CCOCC(=O)N1Cc2ccnn2CC(COCc2ccccn2)C1 +COc1cccc(C(N)=O)c1OCc1cccc(C(=O)N(C)C)c1 +Cc1cccc(C(=O)c2ccccc2CN2CCOCC2)c1 +Cc1nc(NC2=NC(=O)CN2)nc2c(C)cccc12 +c1ncn(CCN2CCN(Cc3ccc(-c4cc[nH]n4)s3)CC2)n1 +CCCS(=O)(=O)NC(C)C(=O)NC(C)(C)CO +CCC(NC(=O)c1cc(Cl)c(OC)c(OC)c1)C1CCCO1 +COc1ccc(NC(=O)N2CCN(c3ccccc3F)CC2)cc1 +Cc1ccc(CN2CCN(C(C)C(N)=O)CC2)s1 +COc1cc(N(C)Cc2n[nH]c3c2CCCCC3)ncn1 +CNC(=O)CN1C(=O)CN=C(c2ccccc2)c2cc(Cl)ccc21 +CCOC(C)C(=O)OCc1coc(-c2ccccc2)n1 +O=C(CC1=CCCCC1)N1CCC(OCc2ccc(F)cc2)CC1 +CCN(C(=O)COC(=O)c1ccc(CO)cc1)c1ccc(F)cc1 +COc1cc(OC)c(-c2cn(C3CCCCNC3=O)nn2)c(OC)c1 +COC(=O)c1ccccc1NC(=O)C12CCC(C)(C(=O)O1)C2(C)C +N#Cc1ccccc1NC(=O)CCC(=O)c1ccccc1 +COc1ccc(OC)c(C(C#N)NCc2ccncc2)c1 +Cc1nc2ccccc2nc1N(C)CC(=O)NC(C)(C)C +O=C(NCc1noc(-c2cccs2)n1)OCC(F)(F)F +Cc1ccc(N2CC(c3nc4ccccc4n3C)CC2=O)cc1C +Cn1ccc(C(=O)N2CCCC(COc3ccc(F)cc3)C2)cc1=O +Cc1cc(C)cc(CCNC(=O)CCNC(=O)c2ccco2)c1 +CN(Cc1ccccn1)C(=O)Nc1ccc(N2CCOC2=O)cc1 +O=C(Cc1cccc(C(F)(F)F)c1)N1CCCC1 +COc1ccc(CN(C)C(=O)Nc2ccc(C(C)=O)c(C)c2)cc1 +CCN1CC(C(=O)N(CCC(N)=O)c2ccccc2)CC1=O +Cc1nnc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)s1 +O=C(c1cscn1)N1CCCC(n2cnc3cc(F)ccc32)C1 +NC(=O)c1ccc(OCc2ccc(F)cc2Cl)cc1 +Cc1nnc(NCc2ccc(C#N)cc2)c(C#N)c1C +Cc1nn(C)c2c1C(c1ccccc1F)=NCC(=O)N2C +Cc1ccc(C(=O)OCCc2cccc(C(F)(F)F)c2)c(=O)[nH]1 +O=C(C1(c2ccncc2Cl)CC1)C1(c2ccncc2Cl)CC1 +CC(C)c1ncc(CN2CCCC(C(=O)N(C)C)C2)s1 +CNc1snc(C)c1C(=O)NC1CCN(c2ncccn2)CC1 +O=C(NCc1nnc2n1CCC2)c1ccc(OC(F)F)cc1 +Cc1nn(C(C)C)c(C)c1NC(=O)CNC(=O)c1cccc(F)c1 +NC(=O)c1ccccc1COc1cccc(Br)c1 +O=C(Nc1cccnc1-n1cncn1)N1CCCCC1c1cn[nH]c1 +Cc1cc(NC(=O)C2CCC2)n(Cc2ccccc2)n1 +Cn1cc(S(=O)(=O)NCC2(c3ccccc3)CC2)c(=O)n(C)c1=O +COc1cccc(C(=O)N2CCN(Cc3ccncc3)CC2)c1OC +CC(C)N(CC(N)=O)C(=O)CCOc1ccccc1Cl +O=C(Nc1cccnc1-n1cncn1)c1cc(Cl)ccc1F +CCOc1cncc(N2CCC(c3nc(C)no3)CC2)n1 +COc1ccc(NC(=O)Cn2ccc3c(C)cccc32)cn1 +CC(Sc1nncs1)C(=O)Nc1ccc(OC(F)(F)F)cc1 +O=C(CCNS(=O)(=O)c1ccccc1)N1CCCC1 +O=C(Nc1ccc(N2CCOCC2)cn1)C1CC(=O)N(CC2CC2)C1 +CC(C)c1nc(CNc2ccccc2C(=O)N(C)C)no1 +Cc1noc(C23CCOC2CCN(S(=O)(=O)CC(C)C)C3)n1 +CN1CCC(NC(=O)c2cncc(Br)c2)C1=O +Cc1ccc(CCC(=O)OCCN2CCCC2=O)cc1 +COCCOc1ccccc1NC(=O)N1CCc2sccc2C1 +COCC(C)CNC(=O)c1cc(Br)c[nH]1 +CCCc1cc(C(=O)NCc2cnn(Cc3ccccc3)c2)no1 +COc1ccc(OCCCC(=O)Nc2ccccc2)cc1 +O=C(CNC(=O)CC1CCCC1)NCc1cn(-c2ccccc2)nn1 +O=C(c1ccoc1)N1CCC(c2nc(-c3ccncc3)cs2)CC1 +O=C(NC1CCCCC1)C1CCCN1C(=O)c1ccc2cc[nH]c2n1 +COCCn1cnc2scc(-c3cccs3)c2c1=O +O=C(Cc1cccs1)Nc1cnn(C2CCOCC2)c1 +Cc1noc(C)c1CC(=O)OCC(=O)c1c(C)[nH]c2ccccc12 +O=C(Nc1ccc(-c2nncn2-c2ccccc2)cn1)c1cnccn1 +COCCOc1cc(NC(=O)Nc2ccc(F)cc2)ccc1OC +Cc1nc(CCNCc2cc(F)ccc2Br)sc1C +COC(=O)Nc1cccc(C(=O)Nc2c(C)cccc2C)c1 +CN(CC(=O)OCc1ccc(-n2cccn2)cc1)c1ncccn1 +Cn1cc(CCNC(=O)N2CCOC(CCc3ccccc3)C2)cn1 +CCS(=O)(=O)N1CCC(C(=O)Nc2cc(OC)ccc2F)CC1 +CCOc1ccc(C(=O)N2CCc3ccc(Cl)cc3C2)cn1 +O=C(C1CCC1)N1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +CCC(C)NC(=O)c1cc(S(N)(=O)=O)oc1C +CC(Oc1ccc(Br)cc1)C(=O)NCCc1ccccn1 +Cc1ccc(C(=O)NCC(=O)NCCc2cccs2)cc1C +Cc1cc(C2CN(Cc3cn(C)nc3C)CCO2)ccc1F +COC(=O)CCCn1cc(Br)cc1C#N +Cc1cc(F)ccc1CNc1ccccc1CCO +COc1cc(COC(=O)Cn2ncc(=O)c3ccccc32)ccc1C +COCc1ccccc1NC(=O)N1CCN(C(=O)c2ccoc2)CC1 +CCC(NCc1ccc(OC)cc1)=C1N=C(c2ccco2)OC1=O +Cc1cc(C(C)NC(C)Cc2c(C)nn(C)c2C)c(C)s1 +N#Cc1ccc(N2CCCC2c2ccc3c(c2)OCCO3)nc1 +CCS(=O)(=O)NCCNc1ccc2nnc(-c3ccccc3)n2n1 +Fc1ccccc1CSc1nnnn1C1CC1 +COc1cccc(-c2nc(C(=O)Nc3cc(OC)ccn3)c(C)[nH]2)c1 +CC(COc1ccc(F)cc1F)NS(=O)(=O)c1ccc(F)cc1 +COc1cc(C)c(C(=O)N2CCC(=O)CC2)cc1C +Cc1cnn(CC2CCCCN2C(=O)CCc2c(C)nn(C)c2C)c1 +COc1c(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)c(C)nn1C +CCCCS(=O)(=O)NCC(=O)Nc1ccc(F)c(F)c1 +Cc1ccc(NC(=O)Nc2nnc(-c3sc(C)nc3C)o2)cc1 +CC(C)=CC1C(C(=O)NCCc2nnc3ccccn23)C1(C)C +COC(=O)CN(C)C(=O)c1cccc(-n2cccn2)n1 +NC(=O)COc1cccc(-c2nc(-c3ccncc3)no2)c1 +CC(C)c1ccc(C(=O)NCc2cn(-c3ccccc3)nn2)cc1 +CC(NC(N)=O)C(=O)NCc1ccnc(Oc2ccc(F)cc2)c1 +Cc1csc(CCn2c(N)nc3ccc(F)cc32)n1 +CCC(=O)Nc1ccc2c(c1)nc(Cn1cccn1)n2CC(C)C +CCn1cnnc1CNS(=O)(=O)N(C)C(C)C +N#Cc1cc(F)ccc1NC(=O)NCc1cccc(C(N)=O)c1 +Cc1nc2ccc(NC(=O)Cc3ccccc3F)cc2o1 +Nc1nn(C(=O)c2cc(Cl)c3c(c2)OCO3)c2ccccc12 +CC(=O)N(C)CC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +CC(=O)N1CCc2cc(NC(=O)Cc3ccc(F)c(F)c3)ccc21 +Cc1ccc(CCNC(=O)c2scnc2C2CC2)cc1 +O=C(Nc1cccc(N2CCCCC2)c1)Nc1ccccn1 +C=CCn1c(C)cc(C(=O)CN2CCOCC2C2CC2)c1C +CC(C)(C)c1ccc(C(=O)NCCC(=O)Nc2nccs2)cc1 +O=C(CSc1nnc(-c2cccs2)n1C1CC1)NC1CCCC1 +Cc1nc(C(=O)Nc2nc3c(s2)CC(C)CC3)cs1 +Cc1nc(-c2nnc(NC(=O)C3CC3)o2)cs1 +Cc1ccc(NCC(=O)Nc2ccc3c(c2)OCO3)cc1 +Cc1cc(OCC(=O)N2CCCC2)ccc1Cl +Cc1cccc(NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)c1 +CCCn1c(O)nnc1SC(C)C(=O)Nc1cccc(C)c1C +O=C(CN1CCN(c2nccs2)CC1)Nc1ccccc1 +Cc1n[nH]c(C)c1NC(=O)Nc1cccc2ccccc12 +O=S1(=O)Nc2c(Cl)cccc2-c2ccccc21 +COc1ccc(OC)c(C(C)NC(=O)c2ccsc2)c1 +NC(=O)C(c1ccccc1)N1CCN(Cc2cscn2)CC1 +O=C(COC(=O)c1[nH]nc2ccccc12)NCCc1ccccc1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)COC +O=C(OC(C(=O)NC1CCCC1)c1ccccn1)c1ccco1 +O=C(COc1ccc(C(F)(F)F)cc1)NC1CC1 +Cc1ccc(CNC(=O)c2cn(C(C)(C)C)c3ncccc23)cc1 +N#CC1(NC(=O)c2cnn(-c3ccccc3)n2)CCCCC1 +COc1ccc(NC(=O)C2(c3ccc(F)cc3)CC2)cc1OC +COc1ccc(N(C)S(=O)(=O)c2cccc(F)c2F)cn1 +COCC(=O)Nc1nc(-c2ccc(CNC(C)=O)o2)cs1 +Cc1ccc2c(c1)NCC(=O)N2CC(=O)OCCC(C)C +Cc1cc(OCC(=O)N2CCn3c(C)nnc3C2)ccc1C(C)C +N#Cc1cccnc1N1CCN(C(=O)NC2CCc3ccccc32)CC1 +CCOC(=O)c1cnc(SC)nc1-c1ccc(OC)nc1 +C=CCN(C(=O)c1ccc(OC)c(Br)c1)C(C)C +CNC(=O)c1ccc(OC2CC2)c(C(F)(F)F)n1 +CCn1cc(C(=O)N2CCC(C(=O)Nc3ccc(F)cc3)CC2)cn1 +Cc1cccc(-n2cc3c(c2-c2ccccc2)c(=O)n(C)c(=O)n3C)c1 +Cc1cc(=O)nc2c3ccccc3n(C(C)C(=O)NC3CCCC3)n12 +COC(C)(CNC(=O)c1cc(C)oc1C)c1ccccc1F +CC(NC(=O)Cn1nnc(-c2ccsc2)n1)c1ccco1 +O=C(c1cccnc1)N1CCN(c2cnccn2)CC1 +CC(C)N1CC(C(=O)N2CCCC2CC(=O)c2ccccc2)CC1=O +CN(C)C(=O)c1ccc(COc2ccccc2Cl)cc1 +O=C(COc1ccc(F)c(Cl)c1)NCCNC(=O)C1CC1 +Cc1ccc(N2CC(C(=O)N(C)CCC#N)CC2=O)c(F)c1 +CC(C)(C)CC(NC(=O)N1CCOCC1)c1ccc(F)cc1 +O=C(c1ccc(F)cc1)c1ccccc1CN1CCOCC1 +N#Cc1ccc(CN2CCN(C(=O)c3ccc(Cl)cc3F)CC2)o1 +CCn1cc(NC(=O)c2ccsc2NC(=O)c2cccs2)cn1 +CCOc1ccc(-c2noc(COc3ccc(C(N)=O)cc3)n2)cc1 +CN(C(=O)c1ccnc(OC2CCC2)c1)C1CCc2ccccc2C1 +Cc1ccc(C(O)CNc2ccccc2C)cc1N +CN1C=NC(O)(c2ccccc2)c2cc(Cl)ccc21 +CC(C)(C)NC(=O)CSc1ccc(Br)cc1 +CCN(CC)C(=O)c1ccccc1NC(=O)NCc1cccc(F)c1 +CCN1CCN(C(=O)c2nccc3c(N)cc(F)cc23)CC1 +Cc1ccc(-c2ccc(C(=O)Nc3ccc(C(N)=O)cc3F)s2)o1 +Cc1ccc(Cl)cc1NC(=O)CCCn1cccc1 +O=C(CNC(c1ccccc1)c1cccc(F)c1)N1CCOCC1 +CC(C)OCCNc1cc(C(F)(F)F)ccc1F +CC1CCCC(CNC(=O)NCc2ccnn2C)C1 +Cc1cc2ccccc2n1CC(=O)N(Cc1cccnc1)C1CC1 +COc1cccc(C(=O)OCC2CCN(CC(F)(F)F)CC2)n1 +Cc1nccn1-c1ncc(-c2nc3ccccc3o2)cn1 +CCS(=O)(=O)c1ccccc1C(=O)NCCc1ccc(F)cc1C +COc1ccccc1OCCn1c(=O)oc2cc(N)ccc21 +Nc1ccc2c(c1)C(c1c(F)cc(F)cc1F)NCC2 +CC(=O)c1csc(NC(=O)Cc2ccc(Cl)cc2)n1 +COC(=O)C1CCCN1Cc1ncc(C(C)(C)C)o1 +Cc1cc(C(=O)CSc2nc(CC3CCCC3)n[nH]2)c(C)[nH]1 +CC(N(C)S(=O)(=O)c1cc(C(N)=O)n(C)c1)C(C)(C)C +COc1ccc(CNC2CCN(c3ccccc3)C2=O)cc1O +Cc1nn(C)c2ncc(NC(=O)N(C)CCOCC3CC3)cc12 +Clc1cccc(CN2CCN(c3nccs3)CC2)c1 +CCN1CC(C(=O)Nc2ccc(C(C)=O)c(C)c2)CC1=O +CCC(C)C(C)NC(=O)CCN1C(=O)CCc2ccccc21 +COc1ccc(C(=O)Oc2ccc(C)cc2OC)nn1 +Cc1nc(OCCNC(=O)C2CCC2)cc(N2CCCCC2)n1 +N#CCCN(Cc1ccccn1)Cc1ccc(CO)o1 +CCSc1ccc(Cl)cc1C(=O)NCc1cc(CC)no1 +Cc1cccc(NC(=O)c2cc3c(cc2C)OCCCO3)c1 +O=C(CCN1CCOC(Cn2cncn2)C1)NC1CCCCC1 +CC(CO)NC(=O)C1CC(=O)N(c2ccccc2Br)C1 +O=C(Nc1c[nH]ccc1=O)c1cc(=O)[nH]c2cc(F)ccc12 +COc1ccc(CC(=O)NCc2nc3ccccc3s2)cc1 +Cc1nn(Cc2noc(-c3ccc(Cl)cc3)n2)c(N)c1C#N +CCC(C)n1ncc(C(=O)Nc2ccc(OC)nc2C)c1C1CC1 +O=C(Nc1cnn(CC(F)(F)F)c1)c1cnn(Cc2ccccc2)c1 +CCNC(=O)c1cc(S(=O)(=O)NCC)c(C)s1 +Cc1cc(OC(F)F)c(C(=O)Nc2cccc3c2OCCO3)s1 +CC(Sc1ccc2c(c1)CCCC2)C(=O)N1CCNCC1 +Cc1c(CN(C)C(=O)Cn2ncc(Br)c2C)cnn1C +N#Cc1ccccc1CSc1nc(-c2cccnc2)n[nH]1 +CCCC(C)c1nnc(NC(=O)Cc2cn3ccsc3n2)s1 +NC(=O)CCN(C(=O)CN1CCc2ccccc2C1)c1ccccc1 +CC(=O)N1CCCC(c2ncncc2-c2cc(C)no2)C1 +COc1cccc(-c2[nH]c3ccc(F)cc3c2C(=O)C2CC2)c1 +CCNc1ncc(C(=O)N2CCN(Cc3cccc(F)c3)CC2)cn1 +CCOCC(O)CN1CCN(C(=O)C2CCc3ccccc32)CC1 +COc1cc(CNS(=O)(=O)N2CCCCC2)ccn1 +COc1ccnc(C(=O)Nc2cc(-c3ncco3)ccc2C)c1 +CCC(C#N)NC(=O)c1cccnc1OCC(F)F +CCOC(=O)CCC(C)NC(=O)c1ccc(=O)n(C)n1 +CC(C)(C)CC(=O)NCCCn1ncc2ccccc21 +CCc1ccccc1CNC(=O)c1cncc(Br)c1 +C#CCOc1ccc(CCNC(=O)N(C)c2c(C)noc2C)cc1 +CC1(C)C(NC(=O)Cc2csc(-c3cccnc3)n2)C2CCOC21 +CC(CC#N)C(=O)c1cc(Cl)c2c(c1)OCCO2 +CCn1c(C)cc(C(=O)N2CCCC2c2ccncc2)c1C +Cc1cc(NC(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2)no1 +CC(C)Oc1ccc(C#N)cc1NC(=O)c1ccc(-n2cncn2)nc1 +O=C(CC(c1ccc(F)cc1)n1cccc1)Nc1cccnc1 +O=S(=O)(NCC#Cc1ccccc1F)c1cccc(F)c1 +Cc1cc(C)n(CC(=O)Nc2ccccc2-c2nnnn2C(C)C)n1 +O=C(C1CC1)N1CCC(c2ncc(-c3ccc(F)c(F)c3)[nH]2)CC1 +CC(C)(CNC(=O)c1ccc(Cl)c(F)c1)c1ccncc1 +O=C(C1Cc2cc(F)ccc2O1)N1CCCC(O)C1 +O=C1CC(c2nc(-c3ccccc3F)no2)CN1c1ccc(F)cc1 +Fc1cccc2c(N3CCOCC3)ncc(Br)c12 +COc1cc(OC)cc(OCc2nnc(C)n2C2CC2)c1 +COc1cccn(CC(=O)N(C)C2CCCc3ccccc32)c1=O +O=C(Cc1c[nH]c2ncccc12)Nc1cnc(-c2ccccc2)nc1 +COc1ccc2[nH]c(=O)c(CCC(=O)NCc3ccco3)cc2c1 +CC(C)C1C(=O)NCCN1Cc1cn2cc(Cl)cc(Cl)c2n1 +CCn1ccc2ccc(NC(=O)N3CCCC3)cc21 +CNc1cc(CNC(=O)Cc2ccc(C)cc2)nc(-c2ccncc2)n1 +CCOC(=O)COc1cc(C)cc2oc(=O)c3c(c12)CCC3 +CC(C)N(C(=O)Cn1cnc(C#N)n1)C1CCCCC1 +CCOCC(=O)Nc1ccc(C#CCCO)c(C)c1 +O=C1CC(Nc2cc(C3CC3)ncn2)CN1c1ccc(F)cc1 +CCOCCNC(=O)Nc1ccc(Oc2ccc(C)cc2)nc1 +CCC(C)N(C)C(=O)COc1ccc(Br)cc1F +COc1cccc(OC)c1-c1nc2ncc(N)cc2o1 +Cc1ccc(C(=O)NCC(=O)Nc2ccccc2)cc1 +CCC(CO)NC1=NS(=O)(=O)c2cc(C)ccc2N1 +COc1cccc(OCC(=O)Nc2ccc(-n3cncn3)c(F)c2)c1 +CCOc1cccc(CNC(=O)c2cccc(C#N)c2)c1 +O=C(Nc1ccncc1)c1ccc(Cl)cc1-n1cnnn1 +CCn1cc(C(=O)N2CCC(NC(=O)c3ccc(C)s3)CC2)cn1 +CCCCNC(=O)CN1C(=O)COc2ccc(Cl)cc21 +O=C(Nc1cc(O)cc(F)c1)C(c1ccccc1)N1CCCCC1=O +CC(C(=O)Nc1ccc(-n2ccnc2)c(F)c1)c1cccs1 +COCC1(CNC(=O)c2cc(C)nn2C)CC(O)C(O)C1 +O=S(=O)(c1ccccc1)N1Cc2cncnc2C1 +O=C(Nc1ccccn1)c1ccc2c(c1)CC(c1ccccc1)OC2=O +Cc1ccc2c(c1F)C(c1ccc(=O)[nH]n1)NCC2 +COc1cc(C#N)ccc1OS(=O)(=O)c1ccc(Cl)cc1F +O=c1nc2oc3cc4c(=O)oc(=O)c5cccc(c3cc2c(=O)[nH]1)c54 +CC1CN(c2ccccc2NC(=O)N(CCC#N)C2CC2)CC(C)O1 +O=C(NCCC(O)c1cccs1)c1ccc2ccccc2c1 +O=C(COCC1CCCO1)Oc1cccc(-n2cccn2)c1 +CN(Cc1cccnc1)C(=O)COc1ccccc1C#N +CC(C)CCNC(=O)N1CCC(CN2CCOCC2)CC1 +COc1cc(C(=O)N(CCC#N)C(C)C)cc(OC)c1C +Nc1ccc(C(=O)NCc2nc(CCOc3ccccc3)n[nH]2)cc1 +Cc1ccc(C(=O)NCCNC(=O)Cc2ccc[nH]2)cc1F +Cn1nccc1CCNC(=O)Nc1cc(F)ccc1-n1cccn1 +COCc1ccc(C(=O)Nc2nc3ccc(OC)cc3s2)cc1 +OC(CNc1ccnc(-c2ccccc2)n1)C1CC1 +Cc1ccnc(NC(=O)C23CCC(C)(C(O)C2)C3(C)C)c1 +CN(CC(=O)N1CCOC2CCCCC21)c1cnccn1 +O=C(Nc1cccc(OCC(F)F)n1)c1ccncc1F +N#Cc1ccc(NC(=O)Cc2c(F)cccc2Cl)cc1 +O=C(NCCNc1cc(-n2cccn2)ncn1)c1cccc(F)c1 +COCCNC(=O)C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +COC(=O)c1nc2nnc(N)n2c(-c2ccc(Cl)cc2)c1C +Cc1noc(C)c1CC(=O)Nc1ccc(C)c2cn[nH]c12 +CCCCS(=O)(=O)N1CCC(C(=O)NCc2cccs2)CC1 +Cn1ccc(C(=O)N2CCCC2c2cncc(Oc3ccccc3)n2)n1 +N#Cc1ccc(Cl)cc1NC(=O)C1CCCO1 +CC(C)n1cccc1C(=O)NC1CCN(C(=O)NC(C)(C)C)CC1 +CCC(CC)NC(=O)Cn1nc(C)c(CO)c1C +CNS(=O)(=O)c1ccc(C(=O)N(C)Cc2ccc(F)cc2)cc1 +CCOc1ccc(C(=O)CCC(=O)N2CCCC(CC)C2)cc1 +Cc1c(N)cccc1NC(=O)c1ccc(Br)cn1 +C=CCN(CC(F)(F)F)C(=O)c1[nH]nc(C)c1Br +CN(C)CC1NCCc2cc(Br)c(O)cc21 +CC(=O)N1CCN(C(=O)c2cccc(-c3ccco3)c2)CC(O)C1 +Fc1ccc(C2CC(c3ccc(F)cc3)n3ncnc3N2)cc1 +Cc1noc(C)c1S(=O)(=O)NC(C)c1ccco1 +CC1CCN(C(=O)Nc2cccc(C(=O)NC(C)(C)C)c2)CC1 +CCc1nc2c(N)cccc2n1CC(=O)N(CC)CC +O=C(Nc1nc(-c2cccnc2)cs1)c1ccc(-n2cccc2)cc1 +Cc1cccc(-c2nnc(-c3ccc(C(=O)NC(C)CO)cc3)o2)c1 +O=C(CSc1nncs1)NCC1(Sc2ccccc2)CC1 +Cc1noc(C)c1CN1CCN(C(=O)c2ccc(N(C)C)nc2)CC1 +Cn1ncc2c(=O)n(CCC(=O)Nc3ccc(Cl)cc3F)cnc21 +Cc1nn(C)c(C)c1NC(=O)CCc1nc2ccccc2s1 +CCOc1ccc2cc(C(=O)Nc3ccc(C)cn3)[nH]c2c1 +Cc1cc(C(=O)NC2(C#N)CCOCC2)c(C)cc1Br +CCc1cccc(C)c1NC(=O)COc1ccc(C#N)cc1OC +CN(C)C(=O)c1ccc(NC(=O)c2ccccc2OC(F)F)cc1 +Cc1ocnc1CNS(=O)(=O)Cc1ccccc1 +CC(C)n1ccnc1CN1CCCN(C(=O)c2ccsc2)CC1 +COc1ccccc1C1CC(c2ccccc2)Nc2nc(N)nn21 +CCCc1cc(C(=O)Nc2ccccc2C)n(C)n1 +CCCc1cc(C(=O)NCC2CCOc3ccccc3C2)no1 +Cn1cnc2c1c(=O)n(CCCSc1ncccn1)c(=O)n2C +CN(C(=O)c1cc2ccoc2s1)c1ccccc1 +CSc1c(C#N)c(=O)oc2c1c(=O)oc1ccccc12 +O=C(c1cccnc1)N1CCC(Oc2ccccc2F)CC1 +Cc1ccn(CCn2ccnc2-c2nn(C)c3cccc(Cl)c23)n1 +Cc1ccc(OC(C)C(=O)NCC2COc3ccccc3O2)cc1 +C=CCN(Cc1ccccc1F)C(=O)C1CC(=O)N(CC)C1 +CCC(=O)N1CCCCC1C(=O)Oc1ccc2cn[nH]c2c1 +O=C(Nc1ccccc1-n1cncn1)c1nccc2ccccc12 +Cc1cc(=O)n(-c2ccccc2)c(=O)n1-c1ccccc1 +Cc1ccc(C(C)C(=O)NCc2nnc(C)s2)s1 +Cc1cc(Cl)c(C)c(S(=O)(=O)N(C)C)c1Cl +CCc1nnc(SCC(=O)N2CCCCCC2)o1 +CCCC1CN(C(=O)COc2ccc(F)c(Cl)c2)CCO1 +Cc1cccc(OCCn2nnc(CO)c2-c2ccncc2)c1 +COc1cccc(CNC(=O)Nc2cc(C)cc3cccnc23)n1 +C#Cc1cccc(NC(=O)CN(C)C(=O)Cc2ccccc2F)c1 +Cc1c(CCC(=O)Nc2ccc(Cl)cc2Cl)cnn1C +CC(=O)N1CCCC1C(=O)Nc1ccc2oc(=O)ccc2c1 +CCC(C)NC(=O)NC1CCN(c2ccccc2)C1=O +CCn1c(C)cc(C(=O)CN2CCC(C(=O)N(C)C)CC2)c1C +O=C(c1ccccn1)N1CCC2(C=CC(N3CCOCC3)CC2)CC1 +NC(=O)c1ccc(NC(=O)CSc2ccccc2)cc1 +O=S(=O)(CC1CCOC1)NCCc1cccs1 +CCN(CC(C)C#N)c1ncnc2sc(C)c(C)c12 +Cc1n[nH]c(-c2cccc(-n3ccnc3-c3cccc4nonc34)c2)n1 +O=C(NCCCO)c1nc(N2CCCC2)ncc1Cl +COC(=O)c1noc(C(=O)NCc2ccccn2)c1N +CN(Cc1cccs1)c1ncnc2c1cnn2-c1ccccn1 +Cc1cc(NC(=O)c2ccccc2)nn1Cc1ccccc1 +CC1CCCN(C(=O)c2ccc(OC(F)(F)F)cc2)C1 +CCC(CC)C(=O)NCc1ccc(OC)c(OC)c1 +CC(Cn1cncn1)NC(=O)N1CCOC(CCc2ccccc2)C1 +CCN(Cc1cccc(-n2cccn2)c1)CC(C)C#N +CC(C)(C)NS(=O)(=O)c1cccc(-c2cc(O)cc(C#N)c2)c1 +COc1ccc(NC(=O)c2ccc(N(C)C)cc2)cc1 +CC(NC(=O)c1cccc(C#N)c1)c1ccc2c(c1)OCO2 +Cc1nn(-c2ccccc2)c(C)c1NC(=O)c1ccoc1C +O=C(c1ccnnc1)N1CCc2ncnc(C3CCOC3)c2CC1 +O=C(CN1CCCNC1=O)Nc1cc(Cl)ccc1NC1CC1 +NC(=O)c1cc(Cl)ccc1OCC(=O)NCc1ccc(F)cc1 +CCc1cc(C(=O)Cn2ccccc2=O)c(O)cc1O +C=CCOc1ccc(Cl)cc1-c1cn(Cc2noc(C)n2)nn1 +NC(=O)Nc1ccc(CNC(=O)c2cccc(C(F)(F)F)c2)cc1 +Cc1ccc(C(=O)Nc2ccc3c(c2)CC(=O)N3)cc1F +CN(C)S(=O)(=O)c1ccc2c(c1)N(Cc1n[nH]c(=O)[nH]1)CC2 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+O=C(Cc1ccc[nH]1)NCC#Cc1cccc(C(F)(F)F)c1 +COC(=O)C(C)Sc1nnc(COc2cccc(C)c2)o1 +CC(Cc1ccccc1F)NC(=O)N1CCC(CC(N)=O)CC1 +Cn1ccc(NC(=O)c2cc(Cl)ccc2F)n1 +Cn1nc(C(C)(C)C)cc1C(=O)NCc1ccc2c(c1)OCO2 +CCOC(=O)c1nc(Cc2c[nH]c3ccccc23)no1 +Cc1nn(C)c(C)c1S(=O)(=O)NC(C)c1ccc(F)c(Cl)c1 +CCCc1cc(-c2ccccc2OC)c(C#N)c(=O)[nH]1 +CC(OC(=O)c1ccc(CCNC(N)=O)cc1)C(C)(C)C#N +Cc1ccc(S(=O)(=O)N2CCN(CC3CCCCO3)CC2)cc1 +CC(C)(C)c1cc2c(=O)[nH]c(CCCS(N)(=O)=O)nc2s1 +CN1CCN(S(=O)(=O)c2ccc(N)cc2)CC1 +CCC(CC)C(=O)Nc1cc2c(cc1Br)OCCO2 +Cc1ncc(Cl)c(C(=O)NCCC(=O)NC2CCCCC2)n1 +COCCCn1c(C2CC2)nc2cc(Cl)ccc21 +CC(C)OCCOC(=O)C1(c2ccccc2F)CC1 +CCCC1CN(C(=O)c2ccc3c(c2O)OC(C)(C)C3)CCO1 +CCOC(=O)COc1ccc(Br)cc1CO +Cc1ccc(F)c(NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)c1 +O=C(c1cccc(F)c1)N(Cc1cccs1)C1CC1 +COCCCNC(=O)Nc1ccc(C)c(C(F)(F)F)c1 +O=C(c1cc2ccsc2n1Cc1cccc(F)c1)N1CCOCC1 +Cc1ccccc1NC(=O)COC(=O)c1cncc(Br)c1 +CCCN(C)C(=O)c1cnn(C(C)CC)c1C1CC1 +CCn1ccc(-c2cc(C(=O)OC)c3c(C)nn(C)c3n2)n1 +O=C(NCCOc1ccccc1)c1cc(-c2ccccc2)on1 +Cc1cc(=O)c(C(=O)NC(C)CC(=O)c2ccc(F)cc2)c[nH]1 +CCNC(=O)c1c(C)nc(N)nc1-c1ccc(OCC(C)C)cc1 +CC(=O)c1ccc(OCC(=O)OCc2cccc(F)c2)cc1 +Cc1c(NC(=O)COc2ccccc2F)cccc1C(N)=O +Oc1cc2c(cc1Cl)CCNC2c1ccc(F)cn1 +CC1CCCN(C(=O)c2cc(S(=O)(=O)N3CCCCC3)c[nH]2)C1 +CC(Sc1ncn[nH]1)C(=O)N(CCC#N)c1ccccc1 +Cn1c(=O)ccn(CC(=O)NC2(C(N)=O)CCCCC2)c1=O +CC(=O)c1cccc(OCC(O)Cn2c(=O)n(C)c3ccccc32)c1 +Nc1cccc(C#Cc2ccc(C(F)(F)F)cc2)c1 +COCc1ccc(C(=O)N(Cc2ccc(C3CC3C)o2)C2CC2)o1 +Cc1noc(C(NCc2ncc(C(C)(C)C)o2)C(C)C)n1 +COCc1cccc(C(=O)NC(C)c2ccco2)c1 +O=C(CSc1ccncc1)NCC1CCCCC1 +Cn1ncc2c(SCC(=O)c3ccccc3)ncnc21 +COc1ccc(OC)c(C(O)CNc2ccc(C)cc2C)c1 +CCN(CC)C(=O)CN(C)C(=O)CC(C)(C)c1ccccc1 +COc1c(Cl)cccc1NC(=O)CCn1cccn1 +COC(=O)c1[nH]c(C)c(C(=O)C(C)N(C)C(=O)c2cccs2)c1C +Cc1cc(C)c(OCC(=O)N(C)CCC#N)c(C)c1 +Cc1ccc(C(=O)NCc2ccccc2Cn2cccn2)o1 +CC(CN1CCOCC1)NC(=O)Nc1cccnc1-n1cccn1 +O=c1nc(SCc2ccncc2)c2c(n1CCO)CCCC2 +O=C(NCCC1CCCCC1)NCc1cn(-c2ccccc2)nn1 +Cc1ccc(NC(=O)c2cccc(CN3CCCC3=O)c2)cc1 +O=C(NCc1cccc(Cl)c1)c1ccc2[nH]cnc2c1 +COc1ccc(C2CCN(S(=O)(=O)c3ccccc3C#N)C2)cc1 +COC(=O)c1cccnc1SCc1ccccc1 +CN(C(=O)Nc1cccc(Cn2cccnc2=O)c1)C1CC1 +Cc1cc(N2CCN(CC3(O)CCCC3)CC2)nc(C(C)C)n1 +CC(C)CC1COCCN1C(=O)NCCNC(=O)C(C)(C)C +Cc1nn(C)c(C)c1CCC(=O)N1CCN(c2nccs2)CC1 +CC(C)C(C)N(Cc1ccco1)C(=O)c1cnn2ccccc12 +CC1CCCN(C(=O)NC2CCCN(C(=O)OC(C)(C)C)C2)C1 +Nc1cc(Br)cnc1NCC1CCCO1 +N#Cc1cccc(S(=O)(=O)NCC2COCCO2)c1 +CCc1sc2nc(C)[nH]c(=O)c2c1Br +Cc1cc(NC(=O)c2ccc(S(C)=O)cc2)c2ncccc2c1 +O=C(NCC(=O)N1CCCC1)c1cc2c(s1)CCC2 +CC(C)c1ccccc1NC(=O)CNc1cccc(C(=O)N(C)C)c1 +O=C(CCc1ccsc1)NCCC(=O)Nc1ccncc1 +CC1CC1c1ccc(CN2CCOC(c3nccs3)C2)o1 +CN(C)C(=O)N1CCC2(C1)C(=O)N(C)c1ccccc12 +Cc1ccc(CC(=O)Nc2cccc(-c3nc[nH]n3)c2)cn1 +C=CCn1c(C)cc(-c2csc(NC(=O)C3CCC3)n2)c1C +O=C(NCc1ccco1)C1Cc2ccccc2N1C(=O)c1ccccc1 +COc1cccc(OC)c1C(=O)Nc1cc(C(N)=O)ccc1C +Nc1cccc(CC(=O)OCc2cccc(Br)c2)c1 +CNC(=O)NC(C)(C)C(=O)Nc1ccc(OC)c(C)c1 +CCc1noc(CC)c1CNC(=O)NCC1(c2ccc(F)cc2)CC1 +Cc1cc(C(=O)Nc2ccc(Cl)cc2)cs1 +COc1cc(C)sc1C(=O)NC(C)C(=O)N1CCCCC1 +CSc1cccc(NC(=O)CCS(=O)(=O)c2ccc(C)cc2)c1 +O=C(CCC(=O)N1CCN(c2ccccc2)C(=O)C1)NC1CCCC1 +CCc1ccc(C(NC(=O)C2CC(=O)N(C)C2)C(C)C)cc1 +CCc1c(-c2csc(CCN3CCOC3=O)n2)[nH]c(C)c1C(C)=O +COCCc1ncc(C(=O)NCCC(C)C)c(N)n1 +COc1ccc(C(=O)N2CCOCC2)cc1NC(=O)C1CC=CC1 +CN(Cc1ccco1)C(=O)Nc1cccc(COCc2ccco2)c1 +Cc1cc(N)c2onc(CC(=O)N3CCCC3)c2c1 +CCn1cc(NC(=O)c2ccccc2Br)ccc1=O +CCCn1nnc(CO)c1-c1cccc(Cl)c1 +Cc1ccc(C#N)c(=O)n1C(C)C(=O)Nc1ccccc1 +COc1ccc(S(=O)(=O)NC(C)Cc2ccco2)cc1F +COC(C)(C(=O)NCC(O)Cc1ccccc1)c1ccccc1 +O=C(c1ccc(Cl)cc1)N1CCN(C(=O)C2CC2)CC1 +CC(O)(CNCc1ccc(Cl)c(F)c1)c1ccsc1 +O=C(Cc1cccc2ccccc12)Nc1cc(N2CCOCC2)ncn1 +Cc1ccccc1CNC(=O)Nc1ccc(Cn2cccn2)cc1 +COc1ccc(C(=O)OCC(=O)Nc2ccccc2C)cc1OC +Cc1c(C)n2c3c(=O)[nH]c(=O)n(C)c3nc2n1-c1ccccc1F +Cc1c(C(=O)NCC(O)c2ccc(C(C)C)cc2)cnn1C +CC(OC(=O)c1ccccc1O)C(=O)Nc1sccc1C#N +CN(C)c1cccc(C(=O)NCCc2ccc3c(c2)OCCO3)c1 +CCOc1ccc(C(=O)N(Cc2ccc(C)s2)C(C)C)cn1 +Cc1ccc2c(CC(=O)N(C)Cc3cc(C)on3)coc2c1 +CN(Cc1ccc(O)cc1)C(=O)c1cccc(F)c1 +CC(=O)c1c(C)nc(C)nc1SCc1cccc(C(N)=O)c1 +CCN(Cc1cccs1)C(=O)CCSc1ccccn1 +CNC(=O)Cn1cc(-c2cnn(Cc3ccccc3)c2)cn1 +Cc1cccn2c(=O)c(C(=O)NCc3cccnc3)c(O)nc12 +CCc1ncc(C(=O)NC(c2ccncc2)c2ccc(C)cc2)cn1 +COC(=O)c1ccc(S(=O)(=O)NC(C)C)cc1 +C=CCNS(=O)(=O)Cc1ccc(NC(=O)c2ccc(C)o2)cc1 +N#Cc1cccc(CNC(=O)Nc2cccc(Cl)c2)c1 +CCOC(=O)c1c(C)[nH]c(C(=O)CNc2ccccc2C)c1C +CCC(=O)c1ccc(N2CCN(C(C)=O)CC2)c(F)c1 +CC(O)CN1CCN(CC(=O)N(C)C(C)c2ccc(F)cc2)CC1 +c1cncc(CCNc2ncnc3ccsc23)c1 +Nc1cc(CCCNC(=O)Cc2cccs2)nn1-c1ccccc1 +COCCN(CC(=O)N(C)C)C(=O)Cn1c(C)c(C)sc1=O +Cn1ncnc1COc1ccccc1C(=O)OC(C)(C)C +Cc1ccc(CCNC(=O)C2CC(=O)N(Cc3cccnc3)C2)o1 +CCCCOc1ccc(C(=O)N2CCC(C(=O)N(C)C)CC2)cc1 +Cc1csc(CN2CCCN(C(=O)Oc3ccccc3)CC2)n1 +O=C(Nc1ccccc1N1CCOCC1)c1cc2ccccc2[nH]1 +Cc1nc(C)c(-c2nc(C3CCOC3)no2)s1 +Cc1ccc(NCCOc2ccccc2)cc1S(=O)(=O)N(C)C +Cn1cc(C(=O)N2CCCC(C)(C)c3ccccc32)ccc1=O +CN(C(=O)c1ccc(=O)n(Cc2ccccc2)n1)c1ccccc1 +O=C(C1CC2CCC1O2)N(CC(F)(F)F)c1ccccn1 +CC(=O)c1cccc(NC(=O)c2nnn(-c3ccccc3)c2N)c1 +O=C(CCCc1ccccn1)N1CCN(C2CCCC2O)CC1 +CCOc1ccc(S(=O)(=O)N2CCOCC2CC(C)C)cc1 +CC(=O)c1ccc(NC(=O)CCc2nncn2-c2ccccc2)cc1C +Cc1cc(NC(=O)C(C)N2CCN(c3ccc(F)cc3)CC2)no1 +CC(C)CCNC(=O)c1ccc(N)c(OCC(C)C)c1 +Cc1cnn(C2CCCC2)c1NC(=O)NC(C)c1ccsc1 +Cc1cc(F)c(F)c(C(=O)N2CCCCC2C)c1 +C=CCNC(=O)C1CCCN(S(=O)(=O)c2cccs2)C1 +CN(Cc1cnn(-c2ccccc2)c1)c1cn[nH]c(=O)c1Cl +CCCCCCNC(=O)Cn1c(=O)oc2cc(Cl)ccc21 +CCCc1cc(NCC2CN(C3CC3)CCO2)n2ncnc2n1 +CCc1n[nH]c(SCC(=O)N(C)Cc2nncn2C(C)C)n1 +Cn1c(=O)oc2ccc(NC(=O)NCC3(c4ccccc4)CC3)cc21 +CC(C)(C)C(=O)NCCC(=O)Oc1cccc(Br)c1 +CCCc1noc(CSc2ccc(N)cc2Cl)n1 +CN(Cc1ccc(-c2ccccc2)cc1)S(=O)(=O)N1CCOCC1 +c1ccc(CC(NCc2cn[nH]c2)c2ccccc2)cc1 +CC(C)NC(=O)N1CCC2(CC1)CC(=O)Nc1ccccc12 +CCN(C1CCCC1)S(=O)(=O)Cc1cccc(N)c1 +CCn1cc(C(=O)Nc2nc(-c3c[nH]c(C(N)=O)c3)cs2)cn1 +CCCc1cc(C2CCCN2S(=O)(=O)CC)no1 +CCC(NC(=O)c1cccc(Cl)c1)c1ccc(OC)c(OC)c1 +CCC(=O)c1cn(CC(=O)NC(C)C)c2ccccc12 +CC(C)CCNc1cc(C(=O)N(C)C)ccc1Cl +O=C(C#Cc1ccccc1)N1CCCCC1CCO +CCc1ccc(C(=O)N2CCN(S(C)(=O)=O)CC2)cc1 +Cc1ccc(C)c(OC(=O)CNC(=O)Cc2cccc(F)c2)c1 +CC(=O)N1CCCCC1(C)C(=O)N1CCC(c2ccnc(C)c2)CC1 +N#CCCn1c(-c2ccccc2N)nc2ccc(F)cc21 +CC(=O)NCc1ccc(C(=O)Nc2nccs2)cc1 +COc1ccc(C(=O)Nc2ccccc2C(=O)NC(C)C)nn1 +Cc1nc(C)c(CCC(=O)Nc2ccccc2C(C)(C)C)c(=O)[nH]1 +CCCN1C(=O)Cc2cc(C(=O)NC3CC3)ccc21 +Fc1ccc(CNCC(F)(F)F)c(Br)c1 +Brc1ccc2c(c1)C(NCc1cscn1)CCO2 +Cc1ccc(C2CCCN2C(=O)c2ccc3[nH]cnc3c2)o1 +CCCc1cc(C(=O)N2CCC3(CN(C)C(=O)O3)C2)cs1 +CC(C)c1noc(CN(C)c2cc(-c3ccccc3)nc3ccnn23)n1 +Cc1nc(C2CCCCCN2C(=O)Cc2c[nH]c3ncccc23)no1 +CCc1noc(CC)c1CC(=O)NCc1cc(=O)[nH]c2ccccc12 +CCc1nc2c(NC(=O)c3cccs3)cccn2n1 +Nc1cc(Cl)ccc1SCCN1CCOCC1 +CCS(=O)(=O)NCCNC(=O)C1COc2ccc(F)cc2C1 +CCC(C)n1cccc(-c2nnc(NCC(C)C)s2)c1=O +COc1cccc(C(N)=O)c1OCc1ccc(SC)cc1 +CC(C)N(CCC#N)C(=O)c1cccc(F)c1F +CNC(=O)C(C)NC(=O)COc1cccc(N)c1 +O=C(CCc1nnc(-c2ccsc2)o1)N1CCCC1c1ccc[nH]1 +CC(=O)Nc1ccc(CCNC(=O)c2cc(F)ccc2F)cc1 +O=C(NCC1CCC1)c1ccc(-c2cccs2)[nH]c1=O +N#Cc1ccc(OCCSc2nncn2-c2ccccc2F)cc1 +COCc1ccc(C(=O)N2CCCC2C(=O)N2CCN(C)CC2)o1 +O=C(COC(=O)c1cc(=O)[nH]c2ccccc12)NCc1ccccc1 +CCCOC(=O)CC1C(=O)NCCN1C(=O)OC(C)(C)C +c1ccc(Cc2n[nH]c(C(c3cccnc3)N3CCOCC3)n2)cc1 +COc1ccccc1CC(=O)NC(C)c1csc(C(C)C)n1 +Cc1c(C(=O)N(C)CC(C)(C)C)nnn1-c1cccc2ncccc12 +COc1ccccc1-c1noc(-c2ccnnc2)n1 +COc1cc(F)c(S(=O)(=O)N(C(C)C)C2CC2)cc1OC +NC(=O)CNC(=O)c1cn(Cc2ccccc2)nc1-c1ccccc1 +Fc1cc2c(cc1Cl)C(c1nc[nH]n1)NCC2 +O=S(=O)(NCCc1ccc(F)cc1F)c1cccc(F)c1 +CCNc1ncc(C(=O)N2CCCC(COc3ccccc3)C2)cn1 +CCn1cc(C(=O)NC(C)COc2cccc(C)c2)cn1 +Cc1ccnn1-c1cccc(NC(=O)N(C)Cc2nccs2)c1 +Cc1ccc(C)c(-c2cc(-c3nc(-c4ccncc4)no3)[nH]n2)c1 +CCNC(=O)N(Cc1ccccc1)c1ccccc1 +CNC(=O)Cn1nc(C2CC2)n(-c2ccccc2)c1=O +CCCCC(=O)Nc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1 +CCC(C)NC(=O)c1ccccc1NS(=O)(=O)c1ccccc1 +N#CCC(=O)NCc1ccccc1OCCN1CCOCC1 +CC(C)CCNC(=O)CSc1nncn1-c1cccc(Cl)c1 +O=C(c1cc2cc(F)ccc2[nH]1)N1CCc2cc(F)ccc2C1 +CC(O)CNc1nc(CN2CCOCC2)nc2sc3c(c12)CCC3 +Cn1nccc1C(=O)OCC(=O)Nc1cccc2ccccc12 +CCCC(=O)N1CCN(C(=O)c2ccccc2OCC)CC1 +CCCN(C)C(=O)Nc1cccc(-n2nnnc2C)c1 +CCOC(=O)NCC(=O)NC1CCC(C(=O)NC)CC1 +CC(C)CCN(C(=O)NCC1CCCO1)C1CC1 +CCNc1cc(C(=O)NCc2c[nH]nc2C)ccn1 +Cc1ccc(=O)n(CC(=O)N2CC(C)CC(C)C2)n1 +COCCN(Cc1ccsc1)C(=O)c1cc(C)oc1C +Cc1ccc(F)cc1NC(=O)C(C)NC(=O)c1ccccc1F +COC(=O)CNC(=O)CNC(=O)Cc1ccccc1 +Cc1cc2sc(NC(=O)N3CCN(C4CC4)C(=O)C3)nc2s1 +NS(=O)(=O)C1CCCN(c2nccc(C(F)(F)F)n2)C1 +CC(O)CNC(=O)c1cc(S(N)(=O)=O)cn1C +CCc1nc(C)c2c(C)c(C(=O)N3CCC(C(N)=O)C3)sc2n1 +Cc1ccccc1C(=O)Nc1ccc2nc3n(c(=O)c2c1)CCCC3 +COc1ncccc1NC(=O)c1ccc(F)cc1Cl +COC(=O)CN(C(=O)c1ccc(C#N)cc1)C1CCCC1 +O=C(CNC(=O)c1cccc(F)c1)Nc1cc(Cl)ccc1O +C#CCNC(=O)c1ccc(=O)n(CC(=O)NCc2ccccc2F)c1 +Cc1cc(N)nc(SCc2cccc(C#N)c2)n1 +CC(C)(C)NC(=O)Nc1ccc(CC(=O)NC2CC2)cc1 +Cc1ccc(OC2CCN(C(=O)Cn3cccn3)CC2)cn1 +Cc1ccc(NC(=O)c2cncn2-c2ccccc2)c(O)c1 +Cc1cc(S(=O)(=O)Nc2ccnn2C(C)C)ccc1F +CC(C)CCNC(=O)NCCN1CCN(c2ccc(F)cc2)CC1 +CCn1c(C)cc(C(=O)OCC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1C +Cc1cc(OC(F)F)c(C(=O)Nc2ccnn2CC(C)C)s1 +COCC1CCCN(C(=O)c2cccc(C#N)c2)C1 +Cc1cc(C)n2nc(C(=O)NCc3cscn3)nc2n1 +O=C(Cn1nccc1-c1ccncc1)N1CCc2ccccc2C1 +CC(=O)NCc1ccc(C(=O)Nc2ccc(C)c(C)c2)cc1 +O=C(Nc1ccc(Br)cn1)c1cc(C(F)(F)F)n[nH]1 +Cc1nc2ccccn2c1C(=O)NCCC(O)c1cccs1 +CCOc1ccc(Cl)cc1CSc1nnc(CC)n1N +CCC(Sc1nnc2c(n1)[nH]c1ccccc12)C(=O)OC +Cc1nn(C)c(C)c1C1NC(=O)c2ccccc2N1 +CC(=O)N1CCN(C(C)C(=O)NCCC(C)C)CC1 +CC(C)CNC(=O)c1ccc(NC(=O)NC(C)(C)C)cc1 +Cc1ccc(NC(=O)C2CCN(C(=O)C3CC3)CC2)cc1F +O=C(Nc1nc(C2CC2)cs1)c1ccc(OCC2CCCO2)cc1 +Cc1ccc(Cl)cc1CNc1ncccc1CO +NC(=O)c1ccc(C2CN(C(=O)c3ccc(F)cc3)CCO2)nc1 +O=C(NC(Cc1ccsc1)c1cccnc1)C1CCOCC1 +Cc1cc(C)cc(CCNC(=O)N(C)Cc2nccn2C(F)F)c1 +CCC(=O)Nc1ccc(NC(=O)c2ccccc2OC)cn1 +CCCNC(=O)C1Cc2ccccc2CN1C(=O)c1ccco1 +CNC(=O)c1cccc(OCc2noc(-c3cccs3)n2)c1 +CCc1ccc(CC(=O)NCCC(=O)N2CCOCC2)cc1 +O=C(NCCCO)c1ccccc1SCc1cscn1 +COCCOC(=O)Cn1nnc2sc3c(c2c1=O)CCC(C)C3 +Cc1cccc(C)c1NC(=O)CNC(=O)C(C)(C)c1ccccc1 +COC(=O)C1C(=O)OC(C)(C)C1C(C)C(=O)c1ccc(F)cc1 +COC(C)C(=O)Nc1cc(Cl)ccc1C(N)=O +O=C(Nc1ccccc1-c1ncc[nH]1)c1cnc(C2CCCO2)s1 +COCCOc1ccccc1NS(=O)(=O)c1cccc(Cl)c1 +CCOc1cc(C=Cc2ncc(C(=O)NC)s2)ccc1OC +Cc1ccc(-c2noc(C(=O)Nc3cccnc3)c2N)cc1 +C#CCN1CCN(c2cccc(C(F)(F)F)c2)CC1 +COc1ccc(CN(C)Cc2cc(=O)oc3ccc(OC)cc23)cc1 +Cc1cc(C2CCCN(C(=O)C3Cc4cc(F)ccc4O3)C2)n[nH]1 +Cc1nc2ccccc2c(-c2ccccc2)c1CC(=O)NC(C)C(N)=O +NC(=O)c1ccc(OCc2nc(-c3cccs3)no2)cc1 +CCS(=O)(=O)N1CC(c2nc(Cc3ccccc3OC)no2)C1 +O=C(Nc1nnc(C(F)(F)F)s1)C1COc2ccc(F)cc2C1 +Cc1ccccc1NC(=O)c1cccc(-n2cnnn2)c1 +COc1ccccc1C1C(C(N)=O)=C(C)OC(N)=C1C(N)=O +COC(=O)CN(C)C(=O)C1CC(=O)N(CC2CC2)C1 +COc1ccc2c(c1)OCC1(CO)CN(c3nccs3)CC21 +C#Cc1cccc(NC(=O)NC2c3ccccc3CC2O)c1 +Cc1ccc(NC(=O)CNc2ccccc2C(N)=O)cc1 +CCc1cc2c(=O)nc(SCCCC#N)[nH]c2s1 +CC(C)(CNC(=O)Nc1nc2ccccc2s1)C(N)=O +O=C(Nc1cccc(N2CCCS2(=O)=O)c1)C1CCC1 +CC(=O)N1CCN(CCC(=O)c2ccccc2)CC1 +CCN(CC)C(=O)CN(C)C(=O)CCc1c(C)nc(C)[nH]c1=O +O=C1CCCCCN1CC(=O)N1CCCOC(Cn2cccn2)C1 +Cc1cc(NC(=O)CSc2ccc3c(c2)OCCCO3)no1 +CC(O)c1ccc(Oc2ccccc2F)c(F)c1 +O=C(NCCN1CCOCC1)c1cc(-c2cccs2)cs1 +CCNC(=O)C(C)Nc1ccccc1S(N)(=O)=O +CC(C)Oc1cccc(CC(=O)Nc2cccnc2)c1 +O=C(Nc1ccccc1-n1cccn1)c1cccc(OCC(F)F)n1 +C(=Cc1ccccc1)COc1cccc(-n2cnnn2)c1 +COc1cc(CC(=O)Nc2cc(-c3ccco3)no2)cc(OC)c1 +CC(C)OC(=O)c1cc(NC(=O)C2CCCO2)ccc1Cl +Cc1nc(COC2COC3(CCN(c4cnccn4)C3)C2)cs1 +COc1ccccc1S(=O)(=O)N1CCC(O)(C(F)(F)F)CC1 +Cc1cc(C(=O)Nc2ccccc2C(C)C)nc2nccn12 +c1cnc(OCC2CCC3C2OCCN3Cc2ccoc2)nc1 +CCOc1cc(C(=O)Nc2cccc(SC)c2)ccc1OC +O=C(COc1cccc2c1NCCC2)Nc1cccc(F)c1 +COC(=O)C1=C(C)C(C(=O)OC(C)C(=O)NC2CC2)=NC1C +COc1ccccc1OCC(=O)N(C)C(C#N)c1ccccc1 +CS(=O)c1ccc(NC(=O)c2ccnc(SC(C)(C)C)c2)cc1 +O=C(CCNC(=O)c1ccsc1)Nc1ccc2[nH]c(=O)[nH]c2c1 +CCn1nnnc1SCCC(=O)Nc1ccc2c(c1)CCC2 +Cc1[nH]c(=O)[nH]c(=O)c1-c1ccc(C(C)N2CCOCC2)cc1 +CC(C)CCn1c(CO)nc2cc(OC(C)C)ccc21 +COc1ccc(CNc2cccc(F)c2C#N)cc1OC +COc1ccc(OCC(=O)Nc2nc(C)no2)cc1 +CCc1nc(CCNC(=O)N(C)C(C)C)cs1 +O=C(CSc1nc2ccccc2[nH]1)c1ccc(O)cc1 +CCN1C(=O)CCC2C1CCN2S(=O)(=O)c1cn(C)cn1 +Cc1cc(NC(=O)CSc2nc3ccccc3s2)ccn1 +Cc1cc(C(=O)NCC2(CO)CCCCC2)c2c(=O)[nH]n(C)c2n1 +O=C(Nc1cccnc1-n1cncn1)c1coc(-c2ccccc2)n1 +COC(=O)c1cccc(COc2ccccc2NC(C)=O)c1 +Cc1ccc(C(=O)Nc2ccc(F)c(C#N)c2)cc1 +O=C(NCC#Cc1ccccc1)c1ccccc1O +Cc1ccn(Cc2cc(=O)n3ccccc3n2)c(=O)c1 +NC(=O)c1ccc(NC(=O)c2nn(-c3ccccc3)c3c2CCC3)cc1 +Cn1ccc(NC(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)n1 +CC(C)(C)c1cc(-c2nc3c4cc(F)ccc4ncn3n2)n[nH]1 +O=C(c1ccccc1F)N(Cc1ccncc1)C1CC1 +CC(C)CCC(=O)NCCS(=O)(=O)c1ccc(Cl)cc1 +Cc1ccc(N(CC(=O)N2CCC(C)CC2)S(C)(=O)=O)c(C)c1 +NC(=O)c1cnn(-c2ncccc2Cl)c1C(F)(F)C(F)(F)F +Cc1cccc(NC(=O)c2cccc(-n3cccc3)c2)c1C(N)=O +Cc1noc(C2CCCN(C(C)c3nc(C(C)(C)C)no3)C2)n1 +CCNC(=O)CN1CCN(C(=O)c2c[nH]nc2C2CCCCC2)CC1 +CCCCn1c(SCC(=O)Nc2ccc(F)c(F)c2)n[nH]c1=O +CC(C)c1ccc(C2CC2C(=O)N(C)C(C)CC#N)cc1 +N#Cc1cccc(NC(=O)CCSc2ncccn2)c1 +Nc1cccc(-c2ccc(SC(F)F)cc2)n1 +Cc1cc(C(=O)NC(C)C)ccc1NC(=O)c1ccncc1F +Nc1nnnn1NCc1cccc(OCc2ccccc2Cl)c1 +Cc1cc(CNC(=O)C2CC(=O)N(c3ccccc3F)C2)ccc1F +O=S(=O)(N1CCCCC1)N1CCc2cc(F)ccc2C1 +COc1cc(NC(=O)CSc2nc(N)cc(=O)[nH]2)cc(OC)c1 +CCc1nc(CC(=O)N2CCCC2c2nc3ccccc3[nH]2)cs1 +COc1ccc(CN(C)S(=O)(=O)Cc2ccccc2C)cc1 +COCc1cc(N2CCC3(CC2)CC(O)CO3)ncn1 +Cc1noc(C)c1CC(=O)N1CC(c2nc(-c3ncccn3)no2)C1 +CCCCCC(=O)c1cccc(S(N)(=O)=O)c1 +O=C(c1ccncc1)N(Cc1ccsc1)C1CC1 +CN(C)c1cccc(C(=O)NC2CCCCC2n2cccn2)c1 +O=C(Nc1nc2cc3c(cc2s1)OCO3)c1cccc(F)c1 +CCc1cc(C(=O)NCCNC(=O)C(C)C)sc1C +COc1ccc(Cl)cc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C +CCC1C=CCN1C(=O)Nc1cc(F)ccc1OC +Cc1nccn1-c1ccc(NC(=O)C2CC=CCC2)cn1 +COCCCNC(=O)c1cc2sccc2n1Cc1cccc(F)c1 +Cc1nn(-c2ccccc2)nc1C(=O)NC(C)c1nnc2n1CCC2 +CC(C)C(=O)N1CCCN(c2ccc(NC(=O)C3CC3)cn2)CC1 +CCNC(=O)CSc1nnc(-c2cccnc2)n1Cc1ccco1 +COc1cc(OC)cc(OCC(=O)NCCO)c1 +CCC(C)(C)C(=O)Nc1cc(C(=O)N2CCOCC2)ccc1C +COc1cc(NS(=O)(=O)c2ccccc2F)c(OC)cc1Cl +COc1cc(OC)cc(C(=O)N2CCC(c3nc(C)cs3)CC2)c1 +Nc1cccc(OCCn2nncc2-c2ccc(F)c(F)c2)c1 +CC(=O)NC(CC(C)C)C1NCCc2cc(F)ccc21 +CC1CC1C(=O)N(C)CC(=O)Nc1ccc(F)cc1 +O=C(NCCN1CCOCC1)c1cc2ccccc2n1-c1ccccc1 +O=C(NCC1CCCO1)c1ncoc1-c1cccs1 +CC(c1ccco1)N(C(=O)Cc1ccc2c(c1)OCO2)C1CC1 +COC1CCc2c(nc(C(=O)C(C)(C)C)n2C)C1 +CCCn1nc(C(=O)NCc2ccco2)ccc1=O +Cc1ccccc1-c1nnc2sc(=Cc3ccco3)c(=O)n12 +CCc1ccc(CNC(=O)Nc2ccc3c(c2)COC3)s1 +N#Cc1cccc(NC(=O)CCCNC(=O)c2ccccc2)c1 +COc1cc(OC)cc(C(=O)NC2(C)Cc3ccccc3C2)c1 +CC(=O)c1cccc(S(=O)(=O)NCc2cnn3ccccc23)c1 +CCC(C)NC(=O)c1ccc(S(=O)(=O)N2CCOCC2)cc1 +CCOc1ccccc1CNc1ccc2[nH]nc(C(N)=O)c2c1 +Cc1cccc(NC(=O)C2CCN(c3nnc4ccccn34)CC2)c1 +CC(=O)NCC1CCN(C(=O)c2ccc(C)s2)CC1 +Cc1ccn2cc(CNC(=O)c3cccc(Cl)c3)nc2c1 +NC(=O)c1csc(C(=O)NC(c2ccccc2)c2ccccc2)c1 +CC(CN1CCOCC1)NC(C)c1cccc(Br)c1 +Cc1noc(CCCC(=O)N(C)Cc2ccccc2-c2ccccc2)n1 +COCCN(C)C(=O)CNC(=O)c1ccsc1 +C=CCNC(=O)c1ccccc1C(=O)c1ccc(F)cc1 +O=C(Cc1cc(-c2ccccc2)on1)N1CCCC1 +CCCc1nnc2sc(Cc3noc4ccccc34)nn12 +COc1cccc(-n2nnc(CO)c2C2CCCO2)c1 +CCCc1noc(Cn2cnc3nc(SC)sc3c2=O)n1 +CCc1nnsc1C(=O)Nc1cnc2n1CCCC2 +COc1ccc(N)c2c(C(=O)NCC(C)C)nccc12 +CCOCCC(=O)Nc1ccc(Br)cn1 +Cc1ccn(C)c(=O)c1NC(=O)CCCc1cc(F)ccc1F +COc1cc(C(=O)Nc2cccc(C#N)c2)ccc1C +N#Cc1cccc(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)c1 +COc1ccccc1NC(=O)Cn1c(CO)nc2ccccc21 +CNC(=O)c1cccc(CCNC(=O)NC2CCc3ccccc32)c1 +COc1c(Br)c(OC)c2c(c1OC)CNCC2(C)C +COc1c(F)cc(NC(=O)c2cccc(-c3nnc(C)o3)c2)cc1F +Cc1ccc(-c2ccc(=O)n(CCC(=O)NCc3ccccc3)n2)cc1 +CCn1nc(NC(=O)c2cc(C)nc3onc(C)c23)cc1C +COc1ccc(NC(=O)N2CCN(c3ccc(O)cc3)CC2)cc1 +CC(C)CS(=O)(=O)c1ccc(C(=O)C(C)C)cc1 +CC(C)(C)c1nn(Cc2ccncc2)c2c1C(=O)CCC2 +CCN(CC(=O)OC)S(=O)(=O)c1ccc(C)c(N)c1 +C#CCNC(=O)NC(C)c1cccc(NS(C)(=O)=O)c1 +CC(CCCO)NC(=O)NC(C)(C)c1ccc2c(c1)OCO2 +Cc1ccc(N2CC(C(=O)OCc3cccnc3)CCC2=O)cc1C +O=C(Oc1ccc(C(F)(F)F)cc1)C1CC=CC1 +Cn1ccnc1C(NC(=O)Nc1cccnc1)c1ccc(Cl)cc1 +CC(NC(=O)NC1(C)Cc2ccccc2C1)C1CCC1 +COc1ccc(NC(=O)c2ccc(C)nc2)cc1Cl +CCC(C)C(CO)NC(=O)c1ccc(C)cc1O +Cn1cc(C(O)CNC(=O)Cc2ccc(Cl)cc2)c2ccccc21 +Cc1cccc2sc(NC(=O)CNC(=O)NCc3ccco3)nc12 +CC1CC1NC(=O)Nc1ncn(C2CCCCC2)n1 +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1cscn1 +CCS(=O)(=O)NC1CCN(c2ncnc3ccc(F)cc23)CC1 +COCCOC(=O)C(C)N1CC(C)Oc2cccc(N)c21 +COC(=O)NCC(=O)N1CCCC(COc2ccc(C)cc2)C1 +CC(C)NC(=O)CNC(=O)NCC#Cc1ccccc1 +Cc1cc(C)[nH]c(=NS(=O)(=O)c2ccc(Cl)cc2)c1 +CC(C)Sc1ccc(NC(=O)c2ccco2)nn1 +Cc1ccc(Cl)cc1N1CCN(CC(O)CO)CC1 +Cc1ccc(-c2cc3c(=O)n(CC(N)=O)ncn3n2)cc1C +COCCN1CC2=C(C1=O)C(c1ccccc1Cl)NC(=O)N2 +O=C(Nc1ccccc1F)c1cc(-c2ccccc2)[nH]n1 +CCOc1c(Cl)cc(CNc2nnnn2C)cc1OC +CCOc1ccc(F)c(C(=O)NC2CCCn3nc(C)nc32)c1F +CCCCNC(=O)Nc1cc(S(=O)(=O)CC)ccc1O +COc1ccc(CNC(=O)c2ccc(-n3ccnn3)cc2)cc1OC +CC(C)(C)c1nnc(SC2CCN(c3sccc3C#N)C2=O)o1 +OCCCCCSc1ncnc2c1cnn2-c1ccccc1 +O=C(Cn1c(=O)oc2ccccc21)NCCc1c[nH]c2ccccc12 +O=C(c1ccc[nH]1)N1CCCC1COc1ccccc1 +COc1ccc(N2CC(C(=O)OCC3CC3)CC2=O)cc1 +CCC1CCc2nc(NC(=O)Cc3c(C)nc(C)[nH]c3=O)sc2C1 +Cc1ccc(OCCN2CCN(C(=O)C3CCCO3)CC2)cc1 +O=C(Cc1ccc[nH]1)NCc1coc(-c2ccccc2)n1 +COc1ccc(CCC(=O)N2CCCS2(=O)=O)cc1 +CCC(C)C(NC(N)=O)C(=O)NC(C)c1ccc(F)cc1Cl +CC(CCc1ccco1)NC(=O)c1csc(S(N)(=O)=O)c1 +COC(=O)Cn1c(-c2ccccc2N)nc2ccc(F)cc21 +Cc1ccnc2nc(C(=O)OCC(=O)Nc3cccc(C#N)c3)nn12 +CC(=O)Nc1nc(CC(=O)Nc2cc(C)ccc2C)cs1 +COc1cccc(CC(=O)OCC(=O)NC2CCCC2)c1 +COc1ccc(F)c(CNC(=O)C2CC(=O)N(C(C)(C)C)C2)c1F +COc1c(O)c(Cl)cc2c1C(CC(C)C)NCC2 +CCS(=O)(=O)N1CCC(C(=O)Nc2nnc(C3CC3)s2)CC1 +OC1CCOC2(CCCCO2)C1OCc1ccccc1 +CC1(C)C2CCC1(CS(=O)(=O)N1CCCCC1)C(=O)C2 +N#CC1CCCC1Nc1ncnc2sc3c(c12)CCCC3 +Cn1cc(C(=O)NCC(=O)Nc2cccnc2)c(-c2cccs2)n1 +CC(C)OCCC(=O)Nc1ccc(F)cc1Cl +O=C(c1csc(-n2cccc2)n1)N1CCc2ccccc21 +Cc1cc(C)n(CCNC(=O)c2nn(C)c3ccc(F)cc3c2=O)n1 +O=c1c(C(F)(F)F)cccn1Cc1cccc2cccnc12 +CC(=O)c1ccc(NC(=O)Cn2nc(C(F)(F)F)n(C)c2=O)cc1 +Cc1cccc(C(=O)N2CCC(CCC(=O)NC3CC3)CC2)n1 +CCC1=C(C(=O)OC)C(c2cc(OC)ccc2OC)n2nnnc2N1 +CCn1c(SCC(=O)NCC(F)(F)F)nnc1-c1ccco1 +CCCn1c(=O)c2ccccc2n2c(SCC(C)C#N)nnc12 +Cc1cc(=O)oc2cc(OCC(=O)Nc3cccnc3)ccc12 +Cc1n[nH]c(C)c1NC(=O)C1COc2ccccc2O1 +Cc1ccc(CN2CCOC3C(OCC4CC4)CCC32)o1 +O=C(Nc1ncccc1Cl)c1ccc(Br)cn1 +CCCc1cc(CN(C)C(=O)c2cc(C)nc3c(C)cccc23)n[nH]1 +O=C(c1ccccc1)N(Cc1ccc(Cl)cc1)CC1CCCO1 +Cn1cc(CNC2COc3ccccc3C2)c2ccccc21 +O=C(NCC1Cn2ccnc2CO1)c1cccnc1 +COCCc1nc(-c2ccc3c(c2)NCCO3)c(C)s1 +CC(Cc1ccsc1)NS(=O)(=O)c1ccccc1 +COc1ccc(C(=O)CSc2nnc(-c3cc(C)n[nH]3)n2N)cc1 +O=C1CCCN1CCCNc1ccc2nnc(C(F)(F)F)n2n1 +N#Cc1ccc(OC2CN(C(=O)C3CC=CC3)C2)cc1 +CCn1ccc(C(=O)OC2CN(c3nc4ccccc4s3)C2)n1 +O=C(Nc1ccc(F)c(F)c1)c1ccc(N2CCCC2=O)cc1 +Cc1cccc(-c2c(C#N)nnn2-c2nnc(C)s2)c1 +Cc1occc1-c1nnc(SCC(=O)N(C)c2ccc(F)cc2)o1 +CCC(C)NC(=O)COc1ccc(Br)cc1 +O=C(c1ccco1)N1CCc2c(c(CO)nn2Cc2ccccc2)C1 +COc1ccc(CC(C)CNC(=O)Nc2ccc(C)nc2)cc1 +COc1cccc(OC)c1C(=O)NC(C)c1ccccc1 +CCNC(=O)CNC(=O)Nc1cc(-c2ccccc2)nn1C(C)C +Cc1cc(=O)c(C(=O)NC2CCN(c3ccc(F)c(Cl)c3)C2)c[nH]1 +Cc1nc(C(=O)NC(C)C2CCCO2)nn1-c1ccc(F)cc1 +Cc1ccccc1OCc1nc(N)nc(C)c1C(N)=O +Cc1cc(Sc2ccccc2N)n2nc(C)nc2n1 +CC(Sc1nnc(NC2CC2)s1)C(=O)Nc1cccc(C#N)c1 +CCOc1ncc(C(=O)OCc2nccn2C(F)F)cc1Cl +CC(C)OCCC(=O)Nc1cccc(-c2nccs2)c1 +O=C(Nc1cnn(CC2CCCO2)c1)Nc1cc(F)ccc1F +COc1ccc(CCC(=O)NC(C)(C)C#N)c(OC)c1OC +CC(C)C(=O)Nc1ccc(OS(=O)(=O)c2cccnc2)cc1 +Cc1ncc(C(=O)Nc2ccc(-c3cn4ccsc4n3)cc2)c(C)n1 +Cc1cc(C)n2nc(SCc3nc(-c4ccsc4)no3)nc2n1 +CCC(=O)Nc1ccc(-c2nc(Cn3cccn3)c(C)o2)cc1 +CC(C)(C)OC(=O)N1CCC(Nc2ccnc(-c3ccccc3)n2)C1 +C=CCN(Cc1ccc2nonc2c1)Cc1ccco1 +O=C(Nc1cc2c(=O)[nH]cnc2cc1F)C1CSc2ccccc21 +CN(CCO)C(=O)Nc1ccc2nc(-c3ccc(F)cc3)oc2c1 +CC(NC(=O)C(C)(C)C)C(=O)Nc1c(F)cccc1N1CCCC1 +C#CCC(OC(=O)c1cnn(-c2ccccc2F)c1)c1ccccn1 +CCOC(=O)CC1NCCc2cc(F)c(C)cc21 +CNS(=O)(=O)c1cc(Br)ccc1OC +Cc1ccc2c(N3CCOCC3)cc(C#N)nc2c1C +CC(O)(CNC(=O)NC1CCN(c2ccccc2)C1)c1ccsc1 +Cc1ccc(C2CC(C(F)(F)F)n3ncc(C#N)c3N2)cc1C +COc1cccc(-c2nn(C(C)(C)C)cc2CO)c1 +COc1cccc(COC(C)C(=O)NCC(=O)N2CCCCC2)c1 +COc1cc(CCc2cc(NC(=O)c3ccoc3)[nH]n2)cc(OC)c1 +CC(=O)Nc1ccccc1OCC(=O)Nc1cccc2ccccc12 +CC1CCN(C(=O)c2cnn3c(-c4ccc(F)cc4)ccnc23)CC1 +Cc1ccccc1NC(=O)C(C)NC(=O)c1ccccc1F +CCCCCCNC(=O)N1CCOC(C(N)=O)C1 +Cn1nnnc1NCc1ccccc1OCc1ccccc1 +Cn1nc(C2CCCN(C(=O)c3cccc(F)c3)C2)c2cccnc21 +Cc1n[nH]cc1CN(CCc1ccccn1)Cc1ccc(F)cc1 +CCC(=O)Nc1ccc(C(C)NC(=O)N(CC(F)F)C2CC2)cc1 +C=C(C)CNC(=O)c1cc(-c2cccc(C)c2)on1 +Cc1cc(S(=O)(=O)N(C)Cc2ccno2)ccc1Br +CN(CC(=O)NC1CC1)c1nn2cc(C(C)(C)C)nc2s1 +O=S(=O)(NC1CCc2ccccc21)c1ccc(F)c(F)c1 +CCN(CC)c1ccc(NC(=O)c2ccc(N3CCCC3)nn2)cn1 +CC(Sc1ccccn1)C(=O)N(C)Cc1ccc(F)cc1 +CCCC(C)(O)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +COc1ccc(C(O)CNCc2ccccc2F)cc1 +O=c1ccc(C2NCCc3cc4c(cc32)OCCO4)n[nH]1 +CCOCCCNC(=O)c1cc(OC)ccc1Br +Cn1c(SCCC(=O)Nc2ccc(F)cc2)nnc1C1CC1 +COc1ccc(F)c(NC(=O)NCc2cc(C(C)C)no2)c1 +CC(=O)N1CCC(NC(=O)c2cc(-c3ccccc3F)on2)CC1 +CN(C)C(=O)CCCC(=O)Nc1ccccc1C(=O)N1CCCCC1 +CCOC(=O)c1nn(-c2ccc(Br)cc2)c(N)c1C#N +CCOC(=O)Cc1nn2c(=O)cc(C)nc2s1 +CC(=O)Nc1cccc(-c2csc(Nc3ncccc3C)n2)c1 +O=C(COC(=O)C1(c2cccc(F)c2)CCC1)N1CCCC1 +O=S(=O)(NCC#Cc1ccccc1)c1cccnc1 +O=c1[nH]c2cc3nc(COCc4ccccc4)[nH]c3cc2[nH]1 +CS(=O)(=O)N1CCC(CNC(=O)Cc2cc(F)ccc2F)CC1 +CCN(CC(=O)NC(C)C)C(=O)CCn1cncn1 +CCOC(=O)c1[nH]c(C)c(S(=O)(=O)NC2CCCCC2)c1C +Cc1cc(C(=O)Nc2ccccc2N2CCOCC2)on1 +COc1cc(-c2cc(NCc3ccccn3)nc3[nH]ccc23)nc(N)n1 +O=c1[nH]c2ccccc2n1Cc1ccccc1Cl +CCc1cc(C(=O)NC2CCCC2)nc2cc(-c3ccco3)nn12 +CCn1cc(C(=O)Nc2ccc(C)c(NC(=O)c3ccncc3)c2)cn1 +Cc1cnccc1-n1nc(C(C)C)nc1CCN(C)S(C)(=O)=O +COC(=O)c1cc(OC)nc2c1c(=O)n(C)c(=O)n2C +CCCNC(=O)N(C)Cc1csc(C#CCCO)c1 +COc1ccccc1NC(=O)N1CCCC(C(F)(F)F)C1 +COc1cccc(C(=O)NCC2COC3(CCCCC3)O2)c1OC +CCCC1CN(C(=O)c2cccc(-c3noc(C4CC4)n3)c2)CCO1 +CC(C)(C)c1ccc(OCC(=O)NCC2CCCO2)cc1 +Nc1cc2c(cc1NC(=O)COc1ccccc1)OCCO2 +CC(Nc1ccc(S(=O)(=O)N2CCCCC2)cn1)c1ccccc1 +Cc1noc(C2CCCN(C(=O)C3CC(=O)N(CC4CC4)C3)C2)n1 +Cc1nc2n(n1)C(CC(=O)Nc1cc(Cl)ccc1C)C(=O)N2 +CCOc1ccc(CNC(=O)Cc2ccc[nH]2)cc1C +Cc1noc(CCCC(=O)Nc2nc(-c3ccccc3)ns2)n1 +CN(Cc1ccccc1F)C(=O)CN1CCOCC1C1CC1 +NC(=O)C1CCCN(c2cnn(-c3ccccc3)c(=O)c2Cl)C1 +CC(C)C(NS(=O)(=O)c1ccccc1F)C(=O)N(C)CCC#N +Cc1cc(COC(=O)c2cccc(NC(N)=O)c2)no1 +Nc1nc2c(ncn2-c2ccc(Br)cc2)c(=O)[nH]1 +CC1COCC(C)N1CC(=O)NC1CCCCC1 +CNC(=O)Nc1ccc(NC(=O)c2cnc(C3CCCO3)s2)cc1 +Cc1ccc(-c2cnc(CCC(=O)N(C)Cc3cc(C)on3)o2)cc1 +Cc1cc(NC(=O)c2ccc(-c3nnc(C)o3)cc2)c2ncccc2c1 +Cc1ccc(NC(=O)c2ccc3nnc4ncn(C(C)C)c4c3c2)cn1 +CC(C#N)CN(C)C(=O)C(C)NC(=O)c1ccccc1 +CCCN(CCC)C(=O)CSc1ccc(N)cc1 +COc1ccnc(NC(=O)C2CC(=O)N(C)C2c2cccnc2)c1 +COc1ccc(Br)cc1-c1ccncn1 +O=C(NC1CCN(C(=O)C2CC2)CC1)C1CCCC1 +CCCNC(C#N)c1c(OC)cc(OC)cc1OC +Cc1ccc(Cc2sc(NC(=O)C3CCC(=O)N3)nc2C)cc1 +CC(C)CC1(CNC(=O)c2ccccc2Cn2cncn2)CC1 +CCCc1cc(NC(=O)Cc2ccc(F)c(F)c2)n[nH]1 +Cn1c(=O)c2c(nc(NCCCO)n2C)n(C)c1=O +CCOc1ccc(CN2CCN(C(=O)c3ccc(C)n3C)CC2)cc1 +Cc1n[nH]c2c1C(c1ccc(Br)cc1)C1=C(COC1=O)N2 +CCc1cccc(C)c1NC(=O)Cn1nccc1-c1ccncc1 +CCOC(=O)CC1NCCc2cc(C)c(F)cc21 +O=c1nc2sc3ccccc3n2c(=O)n1-c1ccccc1 +CCOc1ccc(CNc2ccccc2C#N)cc1 +COc1cc(C(C)=O)ccc1OC(=O)Cc1ccc(F)c(F)c1 +CN(C)C(=O)CNc1ccc(C(F)(F)F)cc1C#N +COCc1cc(NCCc2nc(-c3ccccc3)no2)ncn1 +N#CC(NC(=O)CCOc1ccccc1)c1ccccn1 +CC(CN1CCOCC1)NC(=O)N(C)CC1COc2ccccc2O1 +CCC(NCc1cc(F)cc(Cl)c1)C(=O)OC +CC(=O)Nc1cccc(NC(=O)CN(C)c2ncnc3[nH]cnc23)c1 +Cc1ccc(C=CCC(=O)N(C)Cc2nnc(C3CC3)n2C)cc1 +Cc1noc(C)c1CC(=O)Oc1ccc2c(c1)ncn2C +CC(=O)c1cccc(NC(=O)COc2nnc3ccccn23)c1 +CCc1oc2c(NC(=O)N3CCNC(=O)C3)cc(Cl)cc2c1C +N#Cc1c(CN(Cc2cccnc2)CC2CCCO2)cn2ccccc12 +N#Cc1ccccc1Oc1ccc(NC(=O)NCc2ncc[nH]2)cc1 +COC1CCN(C(=O)c2cc(C(C)C)nc3c2cnn3C(C)C)CC1 +COc1ccc(F)cc1NCc1cc2ccccc2[nH]c1=O +Cc1ccc(C(=O)N(C)Cc2nc3ccccc3c(=O)[nH]2)c(C)c1 +Cc1ccnc(N(C)C(C)CNC(=O)OC(C)(C)C)n1 +Cn1cc(S(=O)(=O)N2CCCC2c2ccco2)c(=O)n(C)c1=O +Cc1ccc(Cc2nc(-c3cccnc3)no2)cc1 +Nc1nc2c([nH]c(=O)n2C2OC(CO)C(O)C2O)c(=O)n1N +Cc1cccc(NC(=O)NCCc2cn3ccccc3n2)c1 +CCOC(=O)CCn1c(=O)ccc2cc(N)ccc21 +COc1cccc(CC(C)NC(=O)N(C)Cc2nccs2)c1 +Cc1[nH]ccc1C(=O)N1CCOCC1CC(=O)c1ccco1 +COc1cc(Cl)c(C)cc1NC(=O)COc1nnc2ccccn12 +N#CCc1cccc(C(=O)NCCc2ccc(O)cc2)c1 +O=S(=O)(Cc1noc(C2CC2)n1)c1ccc(C(F)(F)F)cn1 +C=CCn1c(SCC(=O)N2CC(C)CC(C)C2)nnc1C1CC1 +Cc1sc(=O)n(CC(=O)NC(C)CCc2ccccc2)c1C +CC(=O)NC(C(=O)Nc1nc(-c2ccccc2)ns1)C(C)C +O=C(CSc1ncc2ccccn12)c1ccc(F)c(F)c1 +N#Cc1ccc(C(C(O)Cc2ccc(F)cc2)n2cncn2)cc1 +COc1cc(C(C)=O)ccc1OC(=O)c1cc(-c2ccccc2)no1 +Cc1ccc(C(N)=O)cc1OC(=O)C1CCC(=O)CC1C +CC(C)(C)NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +CN(C(=O)C(C)(C)CS(=O)(=O)N1CCNCC1)c1ccccc1 +CC(C)COCCNC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +Cn1ccnc1-c1cn(Cc2cn3c(n2)SCC3)nn1 +CCc1c(C(=O)N2CCN(CC(=O)NC)CC2)[nH]c(C)c1C(C)=O +CCc1nc2cc(NC(=O)c3cnc4ccccc4n3)ccc2o1 +COc1ccc(F)cc1NC(=O)NCc1cccc2c1OCCCO2 +CN(C(=O)c1cccc(F)c1)C(C#N)c1ccccc1Cl +CC(=O)NC(C(=O)NCc1ccc(-n2cncn2)nc1)C(C)C +COC(=O)Nc1cccc(NCC(=O)NCc2ccc(C)c(F)c2)c1 +COC(=O)CCC(=O)N1CCN(CCC#N)CC1 +CC(C)CNC(=O)C(C)Nc1cccc(N2CCOC2=O)c1 +NS(=O)(=O)N1CCC(C(=O)N2CC=C(c3ccccc3)CC2)CC1 +CCOC(=O)c1cnc2c(C(=O)OCC)cnn2c1C +CNC(=O)c1ccc(Cl)c(NCc2noc(C(C)C)n2)c1 +Cc1cc(C)nc(SCc2ccc(C(=O)NCc3ccco3)o2)n1 +COC(=O)c1cnc2nc(-c3ccc(OC)cc3)nn2c1C +O=C(NCc1ccccc1)c1cccc(C(=O)NCc2ccccc2)c1 +O=C(c1nc(C2CC2)n(-c2ccccc2Cl)n1)N1CC(O)C1 +Cn1c(NC(=O)CCn2cc(Br)cn2)nc2ccccc21 +COCCN(C)S(=O)(=O)c1ccc(Br)c(C)c1 +O=C(Nc1ccccc1N1CCCC1=O)c1ccc(-n2cccc2)cc1 +O=C(COc1nncc2ccccc12)Nc1cccc(Cl)c1 +Cn1cccc1C(=O)N1CC2COCC2(COc2ncccc2F)C1 +O=C(Nc1nccs1)c1ccc(-n2ccnc2)nn1 +CCOc1ccccc1C(=O)Nc1ccc(C#N)cn1 +CC(NC(=O)c1ccn(C2CCCC2)n1)c1ncon1 +Nc1cccc(NC(=O)c2ccc(Br)cc2)c1 +CC1c2cccn2CCN1CC(=O)N1CCc2ccccc21 +COc1csc(C(=O)OCc2nccn2C)c1 +COC(=O)CC(NC(=O)c1cc(C)no1)c1ccccc1 +CC(=O)NCC1CCCN(C(=O)Nc2ccc3c(c2)COC3)C1 +CC(Cn1cccn1)OC(=O)Cc1cccc2cccnc12 +CCNC(=O)c1cccc(NCC(=O)Nc2ccc(Cl)cc2)c1 +COc1ccc(CCSc2nncs2)cc1 +Cc1cccc(OCC(=O)N2CCC(Oc3ccc(C)nc3)CC2)c1 +C#CCOc1ccc(CCNS(=O)(=O)N2CCCCCC2)cc1 +COC(=O)c1ccc(OC)c(OCc2ccccc2)c1 +CCOC(=O)c1ncoc1-c1ccccc1C(=O)N1CCOCC1 +COc1cccc(Cl)c1CC(=O)N(C)c1c(C)noc1C +CCN(CC(C)C#N)C(=O)CN1CCN(c2ccccc2F)CC1 +CCc1ccc(OC)c(S(=O)(=O)Nc2ccccc2O)c1 +CCOC(=O)N1CCN(C(=O)c2ccc3c(c2)CCN3C(C)=O)CC1 +CCS(=O)(=O)c1ccc(-c2cccnc2OC)s1 +O=C(NCc1n[nH]c(=O)c2ccccc12)Nc1ccc(Cl)cc1 +CCCc1sc(C(N)c2cccc(C#N)c2)nc1C +CCOC(=O)c1nnn(-c2cc(Cl)cc(Cl)c2)c1N +Cc1cc(C(=O)N2CCC(Oc3ncccn3)CC2)c(C)o1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)NCCNS(C)(=O)=O +CCOC(=O)C1=C(C)C(C(=O)CN2CC(C)CC(C)C2)=NC1C +COCC(NC(=O)CC12CC3CC(CC(C3)C1)C2)c1ccnn1C +O=C(CC1(O)CCCC1)N1CCN(c2ccc(O)cc2)CC1 +CCC(C)n1ncc(C(=O)NCc2nncn2C2CC2)c1C1CC1 +CC(C)(C)c1nc(CS(=O)(=O)c2ccc3c(c2)OCCO3)no1 +Cc1cc(=O)[nH]c(NCCNC(=O)CCc2scnc2C)n1 +CCC(C)NC(=O)NCc1nc2ccccc2s1 +CC(=O)OC1OC(O)C(C)C2CCC(C)C3CCOC132 +Cc1ccc(NC(=O)N(C)Cc2ccoc2C)cc1 +CCC(=O)N1CCN(C(=O)Nc2cc(-c3ccccc3)on2)CC1 +CCN(CC)C(=O)C(NS(=O)(=O)c1ccc(C)cc1)C(C)C +C=CCNC(=O)c1nnn(-c2cccc(F)c2C)c1C +COc1ccc(C(O)Cc2ccc(Cl)cc2)cc1OC +COCc1ccc(C(=O)N2CCN(C(=O)c3ccoc3)CC2)o1 +Cc1nnc(SCC(=O)c2ccc(NC(=O)CC(C)C)cc2)s1 +Cc1cc(C)n(CC(=O)Nc2ccc(CC#N)cc2)c(=O)c1C#N +Cc1nn2c(C(F)(F)F)ccnc2c1Br +CCc1cnc(NC(=O)NCC(C)(C)c2ccncc2)s1 +Cc1cc(NC(=O)Cc2cn3cccc(C)c3n2)n(C(C)(C)C)n1 +O=C(OC1CCOC1=O)c1cnn(Cc2ccccc2)c1 +CCC(NC(=O)c1cnc2sccn2c1=O)C(C)C +COc1c(F)cc(NC(=O)NCCNC(=O)OC(C)(C)C)cc1F +COc1ccc2ncnc(N3CCCCCC3)c2c1 +O=C(NC1CCN(c2c(F)cccc2F)C1=O)C1CCCO1 +CCC(Sc1nnc(-c2ccoc2C)n1-c1ccccc1)C(N)=O +CCCC1CCC(NC(=O)c2ccc(=O)n(CCOC)n2)CC1 +CC(C)C(=O)NCc1nnnn1-c1cccc(F)c1 +Cn1cc(S(=O)(=O)Nc2ccc(F)c(F)c2)cc1C(N)=O +CC1(C)C(=O)Nc2ccccc2N1C(=O)COC(=O)c1ccco1 +Cn1cc(S(=O)(=O)N2CCOCC2)c(=O)n(C)c1=O +Cc1ccc(NC(=O)Nc2cnn(C3CCOCC3)c2)cc1C +C#CCNC(=O)c1csc(-c2cccc(OC)c2OC)n1 +CCC1c2ccsc2CCN1C(=O)NCCCn1cccn1 +CC(C)NC(=O)C1CCCN1C(=O)c1cc2sccn2c1 +N#Cc1ccc(OCC(=O)Nc2cccnc2)cc1 +CC1CCN(C(=O)CSc2nc(-c3ccc(F)cc3)n[nH]2)CC1 +CC(C)N(C(=O)c1ccccc1-c1ncccn1)C(C)C +CC(=O)Nc1cccc(NC(=O)C2CC3CCC2O3)c1C +CC(C)C(=O)N1CCOC(c2cccc(OC(F)F)c2)C1 +COc1ccnc(CN2C(=O)CCc3ccccc32)c1OC +CC(C)NC(=O)Cc1csc(NC(=O)c2ccc(F)cc2)n1 +Cc1cc(C(O)CCCCO)ccc1OC(C)C +CCCCCNC(=O)NCc1cn2cc(Cl)ccc2n1 +CCCCS(=O)(=O)NCC(=O)Nc1ccc(F)cc1C +O=S(=O)(c1ccc(F)cc1F)N1CCCCCC1 +CCOC(=O)c1cc(C)n(Cc2ccc(F)cc2)n1 +CCc1nc(CN(C)C(=O)CC(C)c2ccccc2F)cs1 +Cc1cnn(CCc2nc(CC(=O)NC3CCCC3)no2)c1 +c1ccc(-n2cccn2)c(CNc2ncnc3[nH]cnc23)c1 +CNC(=O)COc1cccc(CNC(=O)NCC2CC2C)c1 +COc1ccc2c(c1F)C(c1cccc(O)c1)NCC2 +Cc1noc(C)c1C(C)NC(=O)C1(c2ccccc2)CCC1 +Cn1cccc1CN(Cc1cccs1)C(=O)c1cccn(C)c1=O +CCn1nc(C)c(CNC(=O)NCc2cccc(OC)c2)c1C +CC(NC(=O)c1cccs1)C(=O)NCc1ccoc1 +CC(C)(C#N)c1ccc(-c2cc(CO)ccn2)cc1 +CC(=O)N1CCN(c2nc3ccccc3c(=O)[nH]2)CC1 +CCN(CC(F)(F)F)C(=O)c1ccccc1Cl +Cc1nnc(CN2CCN(C(c3ccccc3)c3ccccc3)CC2)o1 +C#CCN1C(=O)C(O)(CC(=O)c2c(C)cc(C)cc2C)c2ccccc21 +CC(C)C(=O)N1CCN(C(C)c2nnc(-c3cccs3)o2)CC1 +CCC(C)C(C(=O)Nc1ccn(C)n1)c1ccccc1 +CCNC(=O)Cn1ccc(NC(=O)C2C(C)(C)C2(C)C)n1 +COCCNC(=O)c1cc(N2CCCC2=O)ccc1Cl +CC(C)CN1CCOC(CNC(=O)C2CC(=O)Nc3ccccc32)C1 +O=C(CCc1ccc(Br)cc1)NC1CCCOC1 +CCN1C(=O)COc2cc(-c3noc(C(=O)NCCOC)n3)ccc21 +Cc1cccc(C(=O)N2CCC3(CCCCC3)C2)n1 +COc1ccc2c(c1)OCC(C(=O)N1CCc3cc(F)ccc3C1)C2 +Cc1ncsc1C(=O)NCC(C)c1cccs1 +Cc1ccccc1CC(=O)Nc1ccc2c(c1)N(S(N)(=O)=O)CC2 +COC(=O)Cn1c(N)nnc1SCc1ccccc1 +CN1C(=O)CCOc2c(N)cc(-c3ccccc3)cc21 +CC1CC(C)CN(C(=O)c2ccccc2NC(=O)NCCO)C1 +CCC(C)Nc1ncnc(Nc2ccc(C(=O)OC)cc2)c1N +O=C(C1COCCO1)N1CCN(c2ncccc2Cl)CC1 +COCCOc1ccccc1C(=O)N(C)Cc1ccc(O)cc1 +COc1ccc(C2CC(c3ccccc3C)n3nnnc3N2)cc1 +CSc1cccc(NC(=O)NC2c3ccccc3CC2O)c1 +Cc1cccc(OC(F)F)c1NC(=O)NCc1ncoc1C +N#Cc1cnn2c1NC(C1CC1)CC2C(F)(F)F +c1cncc(CNCc2ncc(-c3cccc4ccccc34)s2)c1 +COCCNC(=O)C(C)S(=O)(=O)c1nccs1 +COC(=O)c1ccccc1NC(=O)CN1CCOc2ccccc21 +O=C(Cc1ccc[nH]1)N1CCCC1c1ccccc1Cl +O=C(CNc1ccccc1Cl)Nc1ccc(N2CCCC2)cn1 +Cc1nnc(N2CCN(c3ccccc3)CC2)n(N)c1=O +Cc1ccc2c(c1)N(CCCC(=O)NCc1ccccn1)C(=O)CO2 +COc1ccc(F)c(C(=O)N2CCc3cc(F)ccc3C2)c1F +CC(=O)Nc1ccc(NCC(O)c2ccc(Cl)cc2)cc1 +CCN(CC)C(=O)c1ccccc1NC(=O)C(C)c1cccs1 +O=C(Cc1coc2cc3c(cc12)CCC3)Nc1ccncc1 +Cn1cc(NC(=O)c2ccc(OC3CCCC3)cc2)cn1 +CC(=O)Nc1ccc(NC(=O)c2ccc(C(C)=O)s2)cc1C +Cc1nn(C)c(C)c1CC(=O)OCc1cc2c(Cl)cccc2[nH]1 +Cc1nc(CNC(=O)COc2ccc(C)c(C)c2)cs1 +CCC(C)CN(CC)C(=O)c1cnc2ccc(C)cn12 +CSc1cc(C(=O)Nc2cc(C)nn2-c2ccccc2F)ccn1 +CCOc1ccccc1CNC(=O)c1n[nH]c2c1CCC2 +O=S(=O)(Nc1ccccc1O)c1ccccc1Cl +N#CCCN(C(=O)COC(=O)c1cccc(Cl)c1)c1ccccc1 +Cn1cnnc1SCCC(=O)Nc1ccc(F)cc1 +CC(C)NC(=O)CN1CCN(C(=O)C2CC2)CC1 +Cn1ccc(C(=O)Nc2ccc(CN3CCOC3=O)cc2)cc1=O +CC(=O)NCC(=O)NCC(=O)NC(C#N)c1ccc(C(C)(C)C)cc1 +CNC(=O)c1c(C)cccc1NC(=O)COC1CCCCC1C +CC(C)CNC(=O)c1ccccc1C(=O)NCC(C)C +CC1CCCN(S(=O)(=O)c2ccccc2)CC1 +O=C(c1cnn(-c2ccccc2)c1)N1CCC(c2ccccc2F)C1 +CC(C)CCNc1ncnc(N2CCN(c3ccccc3)CC2)c1N +CCCOC1CCCN(C(=O)c2cc(Cl)ccc2O)C1 +CN(C)c1ccc2c(c1)C(c1cnccn1)NCC2 +Cc1noc(C)c1C(C)C(=O)N1CCC(Oc2cccc(Cl)c2)C1 +CN(c1nc2nonc2nc1NCc1cccs1)C1CCOCC1 +O=C(Nc1cc(F)cc(F)c1F)N1CC2CCC(C1)C2O +Cc1ccc(C(=O)N2CCOCC2C2CC2)cc1C +O=S(=O)(c1ccc2c(c1)OCCO2)N1CCOCC1 +CC(=O)c1cc2c(cc1NC(=O)CSc1cn[nH]n1)OCO2 +O=C(c1ccco1)N1CCC(Cn2cnc3ccccc32)CC1 +Cn1cc(N2CC3(CCN(C(=O)c4cccn4C)C3)CC2=O)cn1 +CNC(=O)NCC(=O)N1CCC(Oc2ccc(F)cc2)CC1 +O=C(NCc1nnc2ccccn12)Nc1ccc(-n2cnnn2)cc1 +N#CC(C(=O)CCC1Cc2ccccc2NC1=O)c1ccccn1 +CCCNC(=O)c1nnc2c(Cl)cccc2c1N +O=C(NC1CCN2C(=O)c3ccccc3NC(=O)C12)c1cnccn1 +O=C(Cc1noc2ccccc12)Nc1ccnn1C1CCCCC1 +COc1cc(C=c2sc(=CC(=O)C(C)(C)C)n(C)c2=O)ccc1O +O=C(CC1CCCC1)Nc1ccccc1-n1cnnn1 +CCS(=O)(=O)N1CCCC(c2cnccn2)C1 +COC(C)(C)c1noc(C=Cc2cccc3cccnc23)n1 +O=C1CCc2cc(OC(=O)c3cnn(-c4ccccc4)n3)ccc2N1 +CCCOC(=O)c1cc(-c2ccc(S(C)(=O)=O)cc2)n[nH]1 +CC(=O)N1CCN(C(=O)CNc2ccc(-n3cnnn3)c(C)c2)CC1 +Cc1nonc1C(=O)Nc1ccc(-n2ccnc2C)cc1 +Cc1ccc(OCC(=O)Nc2ccc(N3CCCC3=O)cc2)cc1C +COc1cc(CO)ccc1OCc1cc(C#N)ccc1F +CCOc1ncc(C(=O)Nc2nc3ccc(F)cn3n2)cc1Cl +O=C1CN(C(=O)c2ccc(OCc3ccccc3)cc2)CCN1 +COc1ccc(F)c(NC(=O)NCC(=O)NC2CCCCC2)c1 +C=CCNC(=O)c1ccccc1NC(=O)C(C)Oc1ccc(F)cc1 +COc1ccc(Cl)cc1C(=O)Nn1cnc2ccccc21 +Cc1ccc2cccc(NC(=O)c3cccnc3N3CCCCC3)c2n1 +Cc1ccccc1-c1noc(CN2CCc3cncnc3C2)n1 +CCOc1cccc(NC(=O)CSc2nnc(C(C)(C)C)n2N)c1 +CCn1ccc(C(=O)Nc2cccc(C(F)(F)F)c2)n1 +COC(=O)c1cc(S(=O)(=O)NC(C)(C)C)cn1C +c1ccc(CN2CCC(c3nnc(-c4ccco4)o3)C2)cc1 +CC(Nc1cccc(S(C)(=O)=O)c1)c1cccs1 +CCCn1nc(C(=O)N2CCC3(CC2)OCCO3)ccc1=O +CS(=O)(=O)c1ccc(C(=O)OCC(=O)N2CCCCC2)cc1 +Oc1ccc(C2CNC(c3ccc(O)cc3)CN2)cc1 +Cc1cc(OC(F)F)c(C(=O)Nc2ccc3ncccc3c2)s1 +Cc1cnc(-c2cccc(NC(=O)NC(C)C(C)C)c2)o1 +O=C(NCC1CCCO1)c1cccc(OCc2ccccc2)c1 +COC(=O)c1ccc(OC)cc1OC(=O)C1CC=CCC1 +Oc1ccc2c(c1)OCC2Nc1ccc(Cl)cc1 +Cc1ccc(NCc2ccccc2OCC(=O)N(C)C)cc1Cl +COc1nn(C)cc1C(=O)Nc1ccc(F)cc1F +O=C(NCCc1nnc2ccccn12)c1c[nH]c2ccccc2c1=O +NC(=O)Nc1ccc(C(=O)Nc2cccc(Br)c2)cc1 +CN(C)C(=O)N1CC2COCC(CC(=O)N3CCCC3)C2C1 +Cc1sc(NC(=O)CN2C(=O)COc3ccccc32)c(C#N)c1C +CCc1nnc(SCC(=O)N2CCCCC2)n1N +CCC(C(=O)N1CCCCC1)n1c(=O)[nH]c2ccccc2c1=O +Cc1ccc2[nH]nc(C(=O)Nc3ccc(CC(=O)N(C)C)cc3)c2c1 +Cc1ccc(CNC(=O)C2CC(=O)N(c3ccc(F)cc3)C2)cc1 +CCOc1ccc(C(=O)N2CCN(CCO)CC2)cn1 +COc1cccc(C(=O)NCc2nc3ccccc3[nH]2)c1OC +O=c1cc(C(F)(F)F)nc(NC2CCc3ccccc32)[nH]1 +Cc1cc(C(=O)Nc2cc3c(cc2Cl)NC(=O)CO3)[nH]n1 +CNc1nc(-c2cc(C(=O)OC)ccc2O)ns1 +O=C(Cc1cccc(F)c1)NCc1ccc(CN2CCCC2=O)cc1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)c1ccc(-n2cccn2)cc1 +Cc1nc(NCC2CCCO2)cc(OCC(C)C)n1 +COC(=O)NCC(=O)N1CCCC1c1ccc(C)c(C)c1 +CCCNC(=O)C(C)NC(=O)CC1CCCCC1 +Cc1cccc(C)c1C(C)OC(=O)c1ncn(-c2ccccc2)n1 +Cc1cc(C)n(Cc2ccc(C(=O)Nc3ccc4c(c3)COC4)cc2)n1 +CC(CN1CCOCC1)OC(=O)c1cccc(Cl)c1 +CCCCc1nc(CNc2cc(C#N)ccc2Cl)no1 +N#Cc1ncn(Cc2cc(-c3ccc(Cl)cc3)no2)c1C#N +CC(c1ccccc1F)N1CCN(C(=O)C2CC23CCOCC3)CC1 +CCn1c(C)cc(C)c(C(=O)NCCc2ccc(OC)cc2)c1=O +CCOCC1CCCN(C(=O)Cc2cccc(OCC#N)c2)C1 +CCOc1cccc2c1C(COCCOC)NCC2 +CSc1ccc(C(=O)N(C)CCOCC2CC2)cn1 +COCC(C)NC(=O)CN1CCN(c2cccc(OC)c2)CC1 +CC(C(=O)N1c2ccccc2NC(=O)C1(C)C)N1CCOCC1 +COc1ccncc1NCc1cc(OC)c(OC)c(OC)c1 +O=C(Cc1csc(Nc2ccccn2)n1)Nc1ccccc1 +CC1Oc2ccccc2N(CCC(=O)NC(C)c2cccnc2)C1=O +Cc1cc(C(=O)Nc2nnc(-c3ccn(C(C)C)n3)o2)nn1C(C)C +Cc1cc(OC(=O)C2CCCN2)cc(C)c1Cl +O=c1c2cnc(N3CCOCC3)nc2ccn1CCN1CCOCC1 +CC1(NC(=O)Cc2noc3ccccc23)Cc2ccccc2C1 +CCOCCCNC(=O)c1ccc(N)c(OC)c1 +CC(C)OCCC(=O)Nc1ccc(F)c(C(F)(F)F)c1 +CN(C)C(=O)COc1ccccc1CNc1ccccc1 +Cc1cccc(OCCn2c(-c3ccccc3)noc2=O)c1 +Cc1ccc(CN(C)C(=O)Nc2cccc(N3CCOCC3)c2)s1 +CCOC(=O)N1CCc2nc(NC(=O)c3c(C)cnn3C)sc2C1 +CC(=O)c1cc(C(=O)N2CCC(CC(C)C)C2)c(=O)[nH]c1C +COCCCC(=O)Nc1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +Cc1csc(=O)n1CCC(=O)OCc1cccc2cccnc12 +CCOc1c(S(=O)(=O)N2CCOCC2)ccc(Cl)c1Cl +CC(C)C(c1ccccc1)N(C)C(=O)c1cccc(-n2cccn2)n1 +Cc1cc(C)n(C2CCN(C(=O)CN3CCNC3=O)C2)n1 +Brc1ccc(-c2cn3ccncc3n2)cc1 +CCCCCNC(=O)c1cccc(NC(=O)CC)c1 +C#CCNC(=O)c1ccc(=O)n(Cc2c(Cl)cccc2Cl)c1 +COc1cc2c(c(OC)c1O)C(Cn1cnnn1)NCC2 +COc1cccc(C(=O)OC(C)C(=O)Nc2sccc2C(N)=O)c1 +Cc1cc(C)cc(OCCC(=O)Nc2ccc3c(c2)OCC(=O)N3)c1 +CC1(C)CCCN1C(=O)COc1ccc(Br)cc1 +CN(Cc1ccccc1)C(=O)Cc1noc2ccccc12 +COCCNC(=O)c1ccccc1COc1ccc(F)cc1F +CC(NC(N)=O)C(=O)N(Cc1ccccc1)Cc1ccccc1 +CCOc1ccccc1CNC(=O)C1CCCN1C(=O)c1ccco1 +O=C(NCc1csc(=O)[nH]1)c1ccnc2ccccc12 +N#Cc1ccc(-c2noc(C3CC3c3cc(F)ccc3F)n2)nc1 +CCS(=O)(=O)NCc1nnnn1-c1ccc(F)c(F)c1 +CC(C)NC(=O)CNC(=O)c1cc2sccc2n1C1CCCC1 +COc1ccc(F)cc1NC(=O)Cn1nc2n(c1=O)CCCCC2 +COc1ccccc1NC(C)C(=O)c1ccc2c(c1)CCN2C(C)=O +Cc1cccc(C(=O)Nc2ccc(Oc3cccnc3)nc2)n1 +Cc1ccc(CNC(=O)c2cc3cn(C4CC4)cc3s2)cc1 +CSc1ccccc1NC(=O)CN(C)C(=O)CC(C)C +Cc1ncc(CNc2ccccc2N2CCCC2)s1 +Cc1ccc2c(c1)nc1n2C(CNCc2ccncc2F)COC1 +O=C1CCCCN1CC(=O)N(Cc1ccccc1)CC1(O)CCCC1 +CCc1cnc(C)nc1-c1cc(NCc2ccncc2)nc2[nH]ccc12 +O=S(=O)(c1cccc(F)c1)N1CC(c2nc3ccccc3[nH]2)C1 +Cc1nnc(NC(=O)CSc2nnc(-c3ccco3)n2C)s1 +CCCCNS(=O)(=O)c1ccc(C(C)O)cc1 +COc1cccc(C(C#N)N(C)S(C)(=O)=O)c1 +CN(Cc1ccccc1C#CCO)C(=O)CC1CC1 +CCNC(=O)c1cccc(CNC(=O)c2ccc(-n3ccnn3)cc2)c1 +O=C(Cc1ccccc1)Nc1cccc(NC(=O)c2ccnnc2)c1 +CCn1c(SC)nc2cc(S(N)(=O)=O)ccc21 +COc1ccc(NC(=O)NCC#CCOc2cccnc2)c(OC)c1 +COC(=O)Nc1cccc(NC(=O)Cc2ccc(C)nc2)c1 +Cc1csc(SC(C)C(=O)N(C)CCC#N)n1 +CC(C)(C)c1noc(CCC(=O)N2CCOc3ccccc32)n1 +Cc1nc(-c2cccc(NC(=O)N(C)Cc3c(C)noc3C)c2)n[nH]1 +Cc1csc(C2CN(c3ncnc4c3cnn4C)CCO2)n1 +CCc1nonc1NC(=O)c1cc(Cl)c(OC)c(Cl)c1 +N#CC1(c2nc(-c3cc4ccccc4o3)no2)CCC1 +Cc1ccccc1C(=O)Nc1nnc(-c2ccc3c(c2)OCCO3)o1 +CC(O)c1ccc(OCCOc2cccc3cccnc23)cc1 +CCOCCCNC(=O)c1cccc(-n2nnc3cccnc32)c1 +O=C(NCc1ccc(N2CCCCC2=O)cc1)c1cc2ccccc2[nH]1 +Cc1nc(N2CCCC2C2CCCC2)c2cnn(C)c2n1 +Nc1cccc(C(=O)Nc2cccc(C(F)(F)F)c2)c1 +CCOc1cc(C#N)ccc1OCC(=O)Nc1ccccc1Cl +Cc1ccnc(NC(=O)CC2CCN(C(=O)OC(C)(C)C)C2)c1 +CCCCC(=O)N1CC(C)N(C(=O)CCCC)CC1C +COCC1CCCN(C(=O)c2cccc(Br)c2)C1 +CS(=O)(=O)c1cccc(NCc2cc[nH]n2)c1 +CNC(=O)C1CCCN(c2c(C#N)cnc3c(C)cc(F)cc23)C1 +CC(C)OC(=O)CCc1ncc(-c2ccccc2F)o1 +COCCNC(=O)C(N)c1c(OC)cccc1OC +O=C(NC1CCCC1)C1CCCN(c2ncnc3[nH]cnc23)C1 +O=C1NC2=Cc3ccccc3C2(O)Cc2ccccc21 +Cc1nc2c([nH]1)c(=O)n(C)c(=O)n2CC1CC=CCC1 +CC(C)(Oc1ccc(Br)cc1)C(=O)Nc1cccnc1 +CC(C)(CNC(=O)Nc1ccn(-c2ncccc2Cl)n1)C(N)=O +CN(C)c1ccc(C(=O)NC2CC2c2ccccc2)cn1 +c1nc(NCCOc2ccc3c(c2)CCC3)c2nc[nH]c2n1 +COc1ccc(CCOc2cc(C)c(N)cn2)cc1 +O=C(c1ccc(Oc2ncccn2)cc1)N1CCOCC1 +CCCc1ccc(S(=O)(=O)Oc2cccc(-n3cncn3)c2)cc1 +Cc1cc(C(=O)N2CCCC(c3nn(C)c4ncccc34)C2)cs1 +Cc1ccc(C(=O)Nc2ccc(C(=O)NC3CC3)cc2)s1 +CCC(CS(N)(=O)=O)c1ccc(Br)cc1 +COC(=O)C1=C(c2ccccc2)c2ccccc2S1(=O)=O +COCC(=O)N1CCN(C(=O)NC2CCCCCC2)CC1 +CC(C)=CCN1CC2(CCN(C(=O)C3CCCC3)CC2)CC1=O +COc1cccc(CCNC(=O)C2(C#N)CCCCC2)c1 +O=c1[nH]c2cc(C(F)(F)F)ccc2n(Cc2ccco2)c1=O +CCNC(=O)CCC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +Cc1ccc(NC(=O)CN(C)C(=O)c2ccc(C)c(C)c2)cc1 +CCOC(=O)c1cc(-c2ccc(OC)cc2OC)[nH]n1 +CN(Cc1cnn(C)c1)C(=O)c1cc(Br)cn1C +Cc1ccc(-c2cc(C(=O)Nc3cc(C(N)=O)ccc3C)on2)cc1 +CCOc1cc(C(=O)NCc2cccnc2)ccc1OC +c1ccc(-c2nc[nH]c2-c2cccn2-c2ncccn2)cc1 +O=C(c1nccc2ccccc12)N1CCOC(c2ccccc2F)C1 +CC(=O)N1CCN(C2c3cc(C)ccc3OCC2O)CC1 +CC(C)CN(C)C(=O)C1CCCN(C(=O)NC(C)C)C1 +CCCC(CCC)C(=O)N1CCc2nc(NC(C)=O)sc2C1 +Cc1nc(NC(=O)Cn2cnc(C#N)n2)sc1C +N#Cc1cccc(NC(=O)CSc2nncn2-c2ccccc2)c1 +CN(CCCNC(=O)c1cccc(F)c1)C(=O)c1cccc(F)c1 +NS(=O)(=O)c1ccc(OC2CC2)cc1Br +CCOC(=O)c1cc(-c2cc3cccc(OC)c3o2)nn1C +O=c1ccc(C(F)(F)F)nn1Cc1nccn1C(F)F +CC(C)C(=O)c1ccc(F)c(S(=O)(=O)N(C)C)c1 +CC(=O)N1CCc2ccc(NC(=O)NCc3ccc(F)cc3)cc21 +O=C(Nc1ccc2c(c1)OCCCO2)c1ccc(F)cc1 +COc1ccc(CCc2nc(CC(=O)Nc3ccccc3)no2)cc1 +Cc1ncc(CN2CCCC(c3nccs3)C2)n1-c1ccccc1 +Cc1cccc(OCC(C)NC(=O)C2CCC(=O)NC2)c1 +CC(NC(=O)C(C)n1ccnc1)c1cc(F)ccc1F +Cc1ccccc1S(=O)(=O)Nc1cccc(F)c1 +O=C(Nc1ncc(Cc2ccc(F)cc2)s1)C1CCCO1 +COc1ccccc1CNC(=O)CCc1nc2ccccc2c(=O)[nH]1 +CC(C)n1nccc1NC(=O)COc1ccc2ccc(=O)oc2c1 +CCC(C)C(C)NC(=O)Nc1ccc(F)c(NC(C)=O)c1 +O=C1CC2C(CCN2C(=O)c2cccc(C(F)(F)F)c2)N1 +CCc1nc2cc(NC(=O)NCc3csc(NC)n3)ccc2o1 +Cc1cccc(C(=O)NC(C)C(=O)NCC(C)N2CCOCC2)c1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)N1CC(C)OC(C)C1 +O=C(Nc1cc(F)cc(F)c1)c1ccccc1-n1cnnn1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccc2c(c1)COC2 +CCN(CCO)C(=O)Cc1coc2cc(C)c(C(C)C)cc12 +Cc1cc(C2CCCN2C(=O)c2cnc(-c3ccccc3)nc2)no1 +O=C(NCc1cc(F)ccc1F)NCC(O)c1ccccc1Cl +c1ccc(Cc2noc(CN3CCOCC3C3CC3)n2)cc1 +COC(=O)c1cc(CSc2nnc(-c3ccccc3)n2C)oc1C +Cc1nn(CCC#N)c(C)c1CCC(=O)NC(C)c1cccs1 +Cc1cc(C(=O)NCc2ccccc2Cl)on1 +Cc1ccc(=O)n(C(C)C(=O)N(Cc2ccccc2)c2ccccc2)n1 +N#Cc1ccc(N2CCCN(c3ncccc3C#N)CC2)c(F)c1 +COc1ccc2nnc(CCC(=O)Nc3nc(C)c(C)s3)n2n1 +N#CCCN(Cc1cccc(Cl)c1F)CC1CC1 +CC1=NC2(CCC3CN(C(=O)NC(C)C)CC32)C(=O)N1C +CCN(CC(C)C#N)C(=O)c1nc(S(C)(=O)=O)n2ccccc12 +Cc1ccc(C(=O)Nc2cccc(NC(=O)C(C)n3cccn3)c2)cc1 +CCc1ccc(OC(C)C(=O)Nc2cc(N)ccc2F)cc1 +COc1ccc(-c2nnc(N(C)C)s2)cc1N +COc1ccc(CNc2cnccc2Cl)cc1F +O=C(Nc1cccc2cn[nH]c12)C1(c2ccc(F)cc2)CCOCC1 +CCC(=O)N1CCc2ccc(NS(=O)(=O)C(C)C)cc2C1 +COC(=O)CCNC(=O)N1CC=C(c2ccc(F)cc2)CC1 +COCc1ccc(C(=O)NCC(=O)N2CCCC2)o1 +Cc1cc(C)c(C(=O)CSc2nncn2C)c(C)c1 +CC(=O)Nc1ccc(S(=O)(=O)NCc2cccc(C)n2)cc1 +CNC(=O)c1cc(C2CN(c3ncccn3)CCO2)nc2ccccc12 +CN(Cc1ccccc1)C1(C(=O)NCC(N)=O)Cc2ccccc2C1 +O=C(CNC(=O)c1ccc(C(F)(F)F)cc1)NCc1ccccc1 +CCc1n[nH]c(SCC(=O)Nc2cccc(C)c2)n1 +O=C(NCc1nnc2n1CCCCC2)C1CC(=O)N(C2CCCC2)C1 +Cc1csc(=O)n1CCSc1cccc(C#N)c1 +C=CCNC(=O)CN(c1cc(Cl)ccc1OC)S(C)(=O)=O +Cn1ncc(N)c1C(=O)Nc1nc2ccc(N)cc2s1 +Cc1ccc(C(=O)Nc2ccc3c(c2)OCCCO3)cc1N +CC(C)(CO)NC(=O)Nc1ccc(Oc2cccnc2)nc1 +COc1ccc(CCC(=O)Nc2ncn(Cc3cccnc3)n2)cc1 +O=C(Cn1ccc(C(F)(F)F)n1)Nc1ccc2c(c1)OCO2 +NC(=O)c1cc(Cl)ccc1OCC(=O)Nc1ccc(F)c(F)c1 +O=C(NCCNc1nccc(C(F)(F)F)n1)c1ccccc1Cl +COC(=O)Nc1ccc(NC(=O)Nc2cccnc2)cc1 +CC1CCN(C(=O)c2ccc(NCC(=O)NC(C)(C)C)cc2)CC1 +CC1=C(C(=O)N2CCOCC2)C(c2ccccc2Cl)NC(=O)N1 +CNS(=O)(=O)c1ccc(CCC(=O)NC2CCCCC2C)cc1 +CCCc1cc(CNC(=O)c2ccc(N3CCC(CO)C3)nc2)on1 +O=C(Cc1csc(NC(=O)C2CCCC2)n1)NCc1cccnc1 +Cc1nn(C)c(C)c1C(=O)Nc1cccc(OCCc2ccccc2)c1 +CCn1cnnc1C1CCCN(c2cccc(C(F)(F)F)n2)C1 +CC(C)NC(=O)CNC(=O)c1nn(-c2ccccc2)c2c1CCC2 +COCC(=O)Nc1nnc(CSc2ccccc2)s1 +CC(=O)NCC(=O)Nc1ccc(NC(=O)CC(C)C)cc1 +CCC1CCCCN1C(=O)c1c(C)oc2nc[nH]c(=O)c12 +NC(=O)c1ccc(C(=O)NC(c2ccccc2)C2CC2)cc1 +CC(NC(=O)C1CC(=O)N(C2CCOCC2)C1)c1ccccc1 +COc1cc(C(=O)Nc2ccn(CCN3CCOCC3)n2)ccc1C +COc1cccc(CC(NC(C)=O)C(=O)Oc2ccc(F)cc2)c1 +FC(F)(F)COc1ccc(NCc2ccoc2)cn1 +CC(C)OC(=O)CSc1nnc(N2CCOCC2)n1C +CC(Nc1ccc(-n2cncn2)nc1)C1CCCC1 +COc1cccc(C(=O)Nc2ccc(F)c(C#N)c2)c1O +CCC(C)NC(=O)C(C)NC(=O)Cc1ccsc1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1ccccc1Cl +COC(=O)CCc1csc(-c2cccc(O)c2)n1 +O=C(Cn1cnc(-c2ccccc2)cc1=O)NC1CCCC1 +Cc1cnc(C(=O)NCc2cnc(OCC(C)C)c(Cl)c2)cn1 +CN1CC(C(=O)NCC(=O)N2CCCC2)CC1=O +Cc1cccc(-c2ccc(C(=O)N(C)Cc3cnn(C)c3)c(=O)[nH]2)c1 +Cc1ccccc1C(C(=O)N1CC(N2CCOCC2)C1)N(C)C +CSc1ccc(C2CC(O)=Nc3c2cnn3C)cc1 +Cc1nn(C)cc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +CCn1c(SCc2ccc(C(N)=O)cc2)nc2ccccc2c1=O +CC1CCCN(C(=O)CNC(=O)c2ccc(C(C)(C)C)cc2)C1 +Cn1nc(C2CCN(C(=O)c3ccccc3F)CC2)c2nccnc21 +CCNC(=O)CCC(=O)c1ccc2c(c1)OCCO2 +Cc1cc(NC(C(N)=O)c2ccc(F)cc2)ccc1C(=O)NC(C)C +CN(C(=O)c1cccc(O)c1)C(CCO)c1ccccc1 +COc1ccc(C)cc1NC(=O)CN1CCN(C(=O)C2CC2)CC1 +COc1ccc(C(NC(=O)CC#N)c2ccccc2Cl)c(OC)c1 +CC1CN(Cc2n[nH]c(=O)[nH]2)C(c2ccccc2)CO1 +CC(C)(C)OCCn1cnc2c(F)cc(Br)cc2c1=O +COCCOc1ccc(-c2nccc(N3CCC(O)CC3)n2)cc1 +O=C(c1ccco1)N(Cc1cccc(Cl)c1)Cc1ccco1 +CCN(CC)C(=O)c1onc(-c2cccnc2)c1N +COC(=O)c1c(C)[nH]c(C(=O)OC(C)C(=O)c2ccccc2)c1C +CCOc1cc(F)ccc1NC(=O)N(C)CC1CC1 +Cc1nn(C)c(C)c1CCNC(=O)N1CCCC1C1CCCC1 +CCC(=O)Nc1ccc(S(=O)(=O)N(C)Cc2cc(C)on2)cc1 +Cc1csc(NC(=O)CSc2nnc(-c3ccccc3)n2N)n1 +Fc1cccc(C2CC2c2nc(-c3ccncc3)no2)c1 +CC1CCC(NS(=O)(=O)Cc2ccccc2)CC1 +CC(NC(=O)C(C)(C)c1ccccc1)c1ccncc1 +Cn1ccc(C(=O)NC(Cc2ccsc2)c2cccnc2)n1 +COc1ccc(-c2cc(N)on2)c(Cl)c1Cl +Cc1cc(C(F)F)nn1CC(=O)NCC1CCCOC1 +CCn1c(=O)c(C(=O)NC(C)C)nn(-c2cccc(C)c2)c1=O +CCOC(=O)NC1CCCN(C(=O)CCN2CCOC2=O)C1 +COc1ccc(C2OCCCO2)c(Cl)c1OC +Cc1ccc(C(C)OC(=O)COCC2CCCO2)cc1 +COC(=O)Cc1c(C)c2ccc(OC(C)=O)c(C)c2oc1=O +Nc1cnn(CCc2ccc3c(c2)CCC(=O)N3)c1 +O=C(NCc1ccccc1-c1ccsc1)c1cnn2c1SCC2 +COc1ccc(S(=O)(=O)NCc2ccccn2)cc1C(C)(C)C +CC(C)CCNC(=O)CCS(=O)(=O)c1cccc2nonc12 +CCOc1ccc(NC(=O)N2CCOCC2C2CC2)cc1C +CC(=O)c1ccc(OCC(=O)NC2(C#N)CCCCC2)cc1F +Cc1cc(C)cc(N(C)CC(=O)NCC(=O)N2CCCC2)c1 +O=C(NCCNc1ncccc1C(F)(F)F)Nc1ccccc1F +COc1ccccc1CC(=O)OCC(=O)Nc1ccccc1C +Cc1cc(NCc2cccc(F)c2)n2ncnc2n1 +COC(=O)c1ccc2c(c1)CCN(CC(F)(F)F)C2 +CS(=O)(=O)N(CC(=O)Nc1ccccc1F)c1ccccc1F +COc1ccccc1-n1nnnc1SC(C)C(=O)c1ccccc1 +Cn1cc(S(=O)(=O)NCC(=O)OCc2ccccc2Cl)cn1 +O=C(CN(Cc1cccs1)CC(F)(F)F)N1CCCC1 +CCOC(=O)C1C(C)=NC(C)=C1c1ccccc1OC +CCOc1cc(C)c(C(O)C(=O)NC)cc1Cl +CC1CCC(NC(=O)Cc2c(F)c(F)c(F)c(F)c2F)CC1 +CC(C)c1nncn1CCNc1nc2ccccc2c(=O)[nH]1 +CNC(=O)c1cccc(CS(=O)(=O)c2ccc(OC)cc2)c1 +NC(=O)c1ccc(NC(=O)c2cnc(-c3ccccc3)nc2)cc1 +O=C(Nc1ccc(F)cc1F)c1cccnc1-c1cccs1 +CCOC(=O)N1CCC(OC(=O)Cc2ccc(F)cc2F)CC1 +CCc1onc(C)c1NC(=O)CCSc1ccc(OC)cc1 +Cc1ccc2ncc(C(=O)Nc3ccn(CCc4ccncc4)n3)n2c1 +Cc1ccc(OCC(=O)Nc2ccc(N3CCOCC3)nc2)cc1C +CCc1nc(CNc2ccc(-n3cc(CO)nn3)cc2)no1 +O=S(=O)(Nc1cccc2cccnc12)c1ccc2c(c1)CCO2 +COCCS(=O)(=O)NC1(C#N)CCCCCC1 +O=C(NCC1CCCO1)N(Cc1ccco1)Cc1cccs1 +Cc1csc(CNC(=O)c2cnn(C)c2N)n1 +Nc1nonc1-c1noc(-c2ccc(Cl)cc2Cl)n1 +N#CC1(NCCc2ccc(S(N)(=O)=O)cc2)CCCC1 +CN(CC(=O)Nc1cnn(C)c1)C(=O)c1ccccc1 +Cc1cnc(CCNC(=O)C(C)OCc2ccccc2)s1 +CC(C)(C)n1cc(Nc2ncnc3sccc23)cn1 +Cc1cc2cc(CNc3ccccc3O)c(=O)[nH]c2cc1C +CCOc1ccc(C(=O)N(CC)Cc2cnc3ccccn23)cc1 +Cc1cccc(NC(=O)Cn2c(N3CCOCC3)nc(C)cc2=O)c1 +COc1cccc(C2CN(Cc3cccc(OC)c3OC)CCO2)c1 +CCC(C)Oc1cccc(NC(=O)NC(C)C)c1 +O=C(c1ccc(CN2CCc3ccccc3C2)cc1)N1CCCCC1 +CCOC(=O)c1[nH]c2ccc(Br)cc2c1NC(C)=O +CN(C)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cn1 +CCS(=O)(=O)c1ccccc1C(=O)NCC(=O)Nc1ccccc1 +CCc1onc(C)c1NC(=O)N(CCOC)CC(C)C +Cc1cc(C)n(-c2nccnc2SCc2cccc(F)c2)n1 +COC(=O)COC(c1ccccc1)c1ccccc1 +CCc1cc2c(=O)n(Cc3cccc(OCC(N)=O)c3)cnc2s1 +COc1nc2c(cc1C(=O)NCCC1CC3C=CC1C3)CCC2 +COC(=O)C(CC(C)C)NC(=O)N1CCC(C)CC1 +CC(C)C(=O)NCCNC(=O)C1CC2CCC1O2 +CC(=O)c1c[nH]c(C(=O)NC(c2cccs2)C(C)C)c1 +COc1ccc(CCNC(=O)c2cccnc2-n2cncn2)cc1 +Fc1ccc(F)c(-c2nc(-c3ccc4nncn4c3)no2)c1 +OC(CCN1CCOCC1)c1cc(Br)ccc1F +Cc1cccc(C(=O)N2CCC(C(=O)N(C)C)CC2)n1 +COC(=O)c1c(C)nn2c1ncc1c(=O)n(-c3cccc(C)c3)ccc12 +CC(CNC(=O)Nc1ccc2c(c1)CCC(=O)N2C)c1nccs1 +CC(C)Cn1cc(C(=O)N2CCNC(=O)C2)c2ccccc21 +Cc1ccc(NC(=O)CCC2Cc3ccccc3NC2=O)cc1 +CC(=O)N1CCC(c2nccnc2Oc2ccccc2C)CC1 +O=C(NCc1cccnc1-n1cncn1)c1occc1-c1ccccc1 +Cc1nn(C)c(C)c1C(C)NC(=O)N1CCCC1 +CCC(Cn1nc(-c2ccc(F)c(F)c2)ccc1=O)NC(=O)C(C)C +Cc1ccc2nc(CS(=O)(=O)c3ncccc3Cl)cc(=O)n2c1 +COc1cccc(NC(=O)COC(=O)c2cccc(C)c2O)c1 +Nc1cccc(CCC(=O)Nc2ccccc2Cl)c1 +Cc1nn(C)c2sc(C(=O)OC3CCN(CC(F)F)CC3)cc12 +O=C(Nc1ccc2ccccc2c1)N1CCCC(CO)C1 +CC(C)C(=O)Nc1ccc2c(c1)nc(CN1CCOCC1)n2C(C)C +CC(C)Cc1nc(C(=O)NC2CCCNC2=O)cs1 +CC(C)(C)CN1CC(NC(=O)CCC(=O)c2ccccc2)CC1=O +CC(=O)Nc1c(C)cc(C)cc1NC(=O)c1cc2ccccc2o1 +O=C(NCc1nnc(SCC(=O)N2CCCC2)o1)c1ccco1 +CCOC(=O)CCC(=O)N1CCC(Cc2ccc3c(c2)OCO3)CC1 +CC(=O)Nc1ccc(CN2CCN(c3ccccc3C)CC2)cc1 +O=C1NC2=C(C(=O)N(Cc3ccccc3)C2)C(c2ccc(O)cc2)N1 +N#CC(COC(=O)c1cn2ccccc2n1)Cc1ccccc1 +CCCn1nnnc1COc1ccc(Cl)c(Cl)c1 +CCC(C)c1ccc(NC(=O)CS(=O)(=O)c2ccccc2)cc1 +COc1cccc(-c2cc(-c3nc(-c4ccc(C#N)cn4)no3)[nH]n2)c1 +CCCn1cnnc1CN(C)C(=O)c1nc2c(s1)CCCC2 +COc1ccc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)cc1 +CNS(=O)(=O)c1cc(C(=O)NC(C)c2ccccc2)ccc1OC +NC(=O)CNC(=O)C(Sc1ccc(F)cc1)c1ccccc1 +Cc1nc(C)c(CCNC(=O)N2CCCCC2c2cn[nH]c2)s1 +CN(C)C(=O)c1ccc(C(=O)Nc2ccncc2)cc1 +Cc1nc(CNC(=O)Nc2ccc(OC(C)C)cc2F)c(C)s1 +CC(C)C(C)n1nccc1NC(=O)c1cccc(=O)[nH]1 +COc1cc(NC(=O)Cn2ccc3c(=O)[nH]ccc32)cc(OC)c1 +Cc1ccsc1C(=O)NC(C#N)C1CCCCC1 +Cc1cc(NC(=O)c2ccc3ccccc3c2)ccn1 +COC1(CNC(=O)NC(C)C)C2CC3CC(C2)CC1C3 +CNc1cc(S(=O)(=O)NCCc2ccsc2)ccn1 +CCn1nc2ccc(S(=O)(=O)N3CCCCC3)cn2c1=O +CC1CCC(NC(=O)CSc2n[nH]c(=O)n2C)CC1 +CC(CNC(=O)Nc1cccn(C)c1=O)Cn1cccn1 +Cc1cc(C(=O)N2CCC(c3ccnn3CCO)CC2)cc(C)c1F +O=C(NCc1ccc2c(c1)OCO2)c1cc2c(cn1)OCC2 +CC(=O)c1cccc(NC(=O)C(C)Sc2nc(N)nc(N)n2)c1 +Nc1cncc(-c2cc(C(=O)N3CCCCC3)ccn2)c1 +NC(=O)NC(CC(=O)NCCc1ccccc1F)c1cccs1 +COc1cc2ncnc(NCc3ccc4c(c3)OCO4)c2cc1OC +COc1cccc(CN2CCCC(c3nncn3C)C2)c1OC(C)C +Cc1ncc(Br)c(-c2cc(F)ccc2F)n1 +O=C(CNC(=O)c1ccccc1)Nc1nc2cc(F)c(F)cc2s1 +O=C(NCc1cccc(CN2CCOCC2)c1)Nc1nccs1 +O=C(Nc1cc(-c2ccoc2)nn1-c1ccccc1)c1ccccn1 +COc1cccc(-c2nc(CC(=O)NCCc3c[nH]cn3)cs2)c1 +COC(=O)N1CCC(CNC(=O)Nc2ccc(OC)cc2)CC1 +Cc1ccc(S(=O)(=O)N(Cc2cnn(C)c2)C(C)C)c(Cl)c1 +Cc1cc(C(=O)CN(CC(F)(F)F)C2CC2)c(C)s1 +OC1COc2c(F)cc(Cl)cc2C1N1CCOCC1 +O=C1CC(c2nc3ccccc3[nH]2)CN1Cc1ccccc1 +CCCn1cc(N)cc1C(=O)Nc1cccc(C)c1 +Cc1nn(C)c(C)c1CC(=O)Nc1cnn(-c2ccccc2F)c1 +O=S(=O)(NCCc1c[nH]c2ncccc12)c1cccc(F)c1 +Cc1nc(-c2coc3cc(O)c(C)cc3c2=O)cs1 +CCCCNC(=O)C1CCCN(C(=O)OC(C)(C)C)C1 +Cc1nc(-c2cccc(NCc3cc(F)ccc3F)c2)n[nH]1 +CC(=O)c1cccc(S(=O)(=O)N(Cc2ccccc2F)C2CC2)c1 +CS(=O)(=O)c1ccc(OCCNC(=O)C2CC=CC2)cc1 +Cn1nccc1CNC(=O)NC1(Cc2ccccc2)CCCC1 +CCN1CC(C(C)C)Oc2ccc(C(=O)C(C)N)cc21 +O=C(COC(=O)c1n[nH]c(=O)c2ccccc12)NCc1cccs1 +CC(Cn1nnc2ccccc21)NC(=O)c1ccccn1 +CCc1ccccc1NC(=O)c1ccc2[nH]c(C)nc2c1 +CNC(=O)CSc1nc2ccccc2c(=O)n1CCCOC +CC12CC(NC(=O)N1c1cccc(Cl)c1)c1ccccc1O2 +CCNC(=O)N1CCc2ccc(NC(=O)c3ccc(C)nc3C)cc21 +COCCNC(=O)C1CN(c2nc3c(F)cccc3s2)C1 +CC(C)(C)NC(=O)Nc1ccccc1SCC(N)=O +CCc1noc(CC)c1CNC(=O)NCc1nc(C)no1 +N#Cc1cccc(C(=O)NCC#CCN2CCc3ccccc3C2)c1 +CC(C)COc1ccc(S(=O)(=O)N2CCOCC2)cc1 +COc1ccc(C2CCc3nc(N)nn3C2C)cc1Cl +Cn1nc(CNC(=O)Cc2noc3ccccc23)c2ccccc2c1=O +CNC(=O)NCC(=O)NCC1(N2CCOCC2)CCCCC1 +Cc1cccc(NC(=O)N(CCCO)C(C)C)c1 +CN1CCN(C(=O)c2ccnc(-c3cccc(N(C)C)c3)c2)CC1 +COc1cc(C#N)ccc1CN(C)C(C)c1ccccn1 +Cn1ncc(C(=O)N2CCOC(c3ccccc3)C2)c1-n1cccc1 +NC(=O)CCOc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1 +O=C(NCCCOC1CCCc2ccccc21)C1CCCO1 +O=C(NCc1ccc2c(c1)CCO2)Nc1ccccc1 +O=C(Nc1ccccn1)c1ccc2c(c1)nnn2Cc1ccccc1 +Cc1ccc(S(=O)(=O)NCCC(=O)Nc2cc(C)ccc2C)cc1 +CC(C)c1cc(NC(=O)CS(=O)(=O)c2ccccc2Cl)on1 +Cc1cccc(C2(CNC(=O)C(C)NC(N)=O)CCCCC2)c1 +NC(=O)CNC(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +O=C(Cc1ccc(F)cc1)N1CCn2cc(Cn3cncn3)nc2C1 +CC1CCCCN1C(=O)CSc1ccccc1F +Cc1ccoc1C(=O)Nc1ccccc1SCCC#N +CCOCc1c(C(=O)Nc2ccc(N(C)C)nc2)oc2ccccc12 +CN(C(=O)c1ccnc(NCC2CC2)c1)c1ccccc1 +COc1cc(O)c2c(c1)C(C1CCC(=O)N1)NCC2 +N#CCCCOc1cccnc1NC(=O)c1cc2ccccc2o1 +CC(C)C(C)NC(=O)Nc1ccc(-n2cccn2)nc1 +CN(C)C(=O)CCNS(=O)(=O)c1ccc2c(c1)CCC2 +COc1ccc(NC(=O)c2ccc(C)c(Cl)c2)cc1N +COc1ccccc1NC(=O)c1cnc(N2CCOCC2)nc1C +Cc1cccc(C)c1NC(=O)CSc1nncn1-n1cccc1 +COc1ccccc1OCC(=O)N(C(C)C)C1CCC1 +CN(CC(O)C1CC1)C(=O)CCC(=O)c1ccccc1 +CC(C)(C)Nc1ncnc(NCc2ccc(Cl)cc2)c1N +Cc1nn(-c2ccccc2)c(C)c1-c1ccnc(N)n1 +CC(C)C(Oc1ccccc1C#N)C(=O)N(C)CC1CC1 +COc1ncc(NCc2cc(C#N)cs2)cc1C(N)=O +CC(C)c1nnc(NC(=O)CSc2nc(N)cc(=O)[nH]2)s1 +O=C(Nc1ccccc1SCC(F)(F)F)c1ccnnc1 +Cc1cccc2c1cnn2CCC(=O)N1CCCCCC1 +CCC(NC(=O)c1cc(C(F)(F)F)ccc1F)c1nc(C)n[nH]1 +COc1ccc(F)cc1C(=O)c1ccc(N2CCCC2)o1 +CCCNC(=O)CSc1nc2nc(C)cc(C)n2n1 +CCc1cc(=O)c2cc(NC(=O)Cc3ccn[nH]3)ccc2[nH]1 +O=C(c1c[nH]cn1)N1CCCn2c(nnc2Cn2cccn2)C1 +COc1cccc(NC(=O)Cn2ncccc2=O)c1 +N#Cc1nnn(CCO)c1-c1ccc(F)c(F)c1F +COc1ccc(C(=O)OCC(=O)Nc2ccccc2C)c(F)c1 +CCCn1c(N)c(C(=O)CSc2nnc(C)[nH]2)c(=O)[nH]c1=O +O=S(=O)(NCC(O)c1ccsc1)c1ccc2c(c1)OCCO2 +C=CCCOCCNC(=O)Nc1ccc2c(c1)COC2 +N#CCc1ccc(NC(=O)c2ccc3c(c2)CCC3)cc1 +CCN(CC)S(=O)(=O)c1ccc(O)c(NC(=O)C2CC2)c1 +Cc1ccc(CN(C(=O)CN2CCN(CCO)CC2)C2CC2)cc1 +c1cc(C2CCCC2)nc(NCc2nccs2)n1 +CCOC(=O)CCC(C)NC(=O)c1ccc(C)c(C)c1O +COc1cccc(NC(=O)c2cccc(-c3nnnn3C(C)C)c2)c1 +COC(=O)c1ccc(CNC(=O)CN(C)c2ccccc2)cc1 +COC(=O)COc1cccc(NC(=O)CC2CCCC2)c1 +Cc1nc(N)cc(N2CCC(N3CCOC3=O)CC2)n1 +O=C(Cc1ccc(-c2ccccc2)cc1)NCC1(O)CCOCC1 +O=C(Nc1ccc2c(c1)COC2)N(CCC(F)(F)F)CC(O)CO +CCc1onc(C)c1NC(=O)Cc1cc(Cl)ccc1OC +CC(=O)c1ccc(C(=O)NCCNc2cnccn2)s1 +COc1ccc(C(=O)Nc2ncc(C)s2)c2ccccc12 +Cc1ccc(C(C)C)cc1OC(=O)Cn1ncc(=O)c2ccccc21 +Cc1nc2nc3cc[nH]c(=O)c3c(-c3ccc(F)cc3)n2n1 +CCc1ncc2c(n1)CN(C(=O)c1ccc(F)c(OC)c1F)C2 +CCC(CNC(=O)N1CCC(OC)CC1)Oc1ccccc1Cl +COCCN(Cc1cnn(C)c1)C(=O)c1cnc(C)cn1 +CC1CCCCN1C(=O)Nc1ccc(F)cc1F +Cc1cc(C)n2nc(SC(C)C(=O)Nc3ccccc3C)nc2n1 +Cc1c(NC(=O)NCC2CC2)cccc1C(=O)N1CCOCC1 +O=C(NCCCOc1ccc2c(c1)OCO2)c1cccc2ccoc12 +COc1cc(NC(C)c2ccccc2)nc(C2CC2)n1 +CCN1CCc2nc(NC(=O)c3csc4c3CCCC4)sc2C1 +CC(=O)c1ccc(OCC(O)Cn2cnc3ccccc32)cc1 +CC(=O)c1ccccc1NC(=O)c1nn(-c2ccccc2)nc1C +COC(=O)CNC1CS(=O)(=O)c2ccccc21 +CCOC(=O)Cc1cc(C(=O)c2cccnc2)c(N)o1 +Cc1cc(C(=O)Nc2c(C)nn(C)c2C)nc(N(C)C)n1 +Cc1ccc(C(=O)NCC(=O)Nc2ccc(F)c(F)c2F)cc1 +CCc1nc(CCNC(=O)Nc2ccc3c(c2)COC3)cs1 +COc1cc(CN2CCOC(c3cccs3)C2)cc(OC)c1OC +CCn1nc(CNC(=O)c2ccc(C#N)cc2)c2ccccc21 +CCCC1CN(C(=O)C(C)Sc2ccccn2)CCO1 +Cc1cccc2c1CCN2C(=O)c1ccnc(OC2CCOC2)c1 +COc1ccc(OC)c(CN(C(=O)c2cc(C)on2)C2CC2)c1 +N#Cc1ccc(NCCC(=O)Nc2ccc(Br)cc2)nc1 +COC(=O)c1cccc(CCNC(=O)c2ccc[nH]2)c1 +COc1nccnc1NC1CCN(S(C)(=O)=O)CC1 +COc1cccc(C(=O)NC2CNc3ccccc3C2)c1 +COC(=O)C(C)(C)NS(=O)(=O)c1ccc(-n2cccn2)c(F)c1 +O=C(Cn1cc(Br)ccc1=O)NC1CCCCCC1 +CCc1nc2n(n1)CCCC2NC(=O)C(C)Sc1ccccc1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)NC2CCCCC2)c1C +COC(=O)c1ccc(S(=O)(=O)NC(C)c2cc(C)oc2C)cc1 +COC(=O)c1ccc(C)c(NC(=O)c2csc(C)c2)c1 +COCCn1ccc(NC(=O)CNC(=O)c2ccccc2)n1 +O=C(NCCS(=O)c1ccccc1)C1CC1c1ccccc1Cl +CC(COCC(F)(F)F)Nc1ccc(Cl)c(C#N)n1 +CCN(C(=O)CCSc1ccccn1)c1ccccc1 +Cc1cn(CCNC(=O)Cn2ccnc2-c2ccccc2)nn1 +CC1CCc2sc3nc(-c4ccco4)[nH]c(=O)c3c2C1 +O=c1c2cc(Br)ccc2ncn1CCO +Cc1occc(=O)c1OCC(=O)Nc1cc(F)c(F)c(F)c1 +O=C(c1cc2ccccc2s1)N1CCN(CC2COCCO2)CC1 +Cc1cccc2sc(NC(=O)COc3ccc(C(N)=O)cc3)nc12 +CCCNS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +O=C(CCCSc1ccc(Br)cc1)N1CCOCC1 +COc1ccc(C(=O)NC2(c3noc(C)n3)CCCC2)nn1 +CCOC(=O)C(NC(=O)OC(C)(C)C)c1ccccn1 +CC(=O)Nc1cc(NC(=O)NCC(=O)N(C)C)ccc1C +CNC(=O)c1cccc(OC(=O)CCc2cnn(C)c2)c1 +COc1ccc(C(O)CCCC(=O)NC2CC2)cc1C +O=C(NCC(=O)N1CCCC1)c1ccc2ccccc2n1 +Cc1cccc(N2CC(C(=O)NCC3CCC3)CC2=O)c1C +Cc1c(C(=O)NCCc2ncon2)c(=O)[nH]c2ccccc12 +O=C(CCC(=O)N1CCCCCC1)c1ccc2c(c1)CCC2 +Cc1cncc(C(=O)N2CCCC(O)(CO)C2)c1 +CCN(Cc1ccccc1NCC(=O)NC1(C#N)CCCC1)C(C)=O +CC(C)C(=O)Nc1ccccc1C(=O)NCc1cccnc1 +O=C(Nc1cnc2c(c1)COCC2)c1ccc(F)c(F)c1 +CCCC(=O)NC(C)c1ccc2c(c1)NC(=O)CO2 +Nc1nncn1C(=O)c1ccccc1CCc1ccccc1 +Cn1nc(-c2cccs2)cc1C(=O)NCCc1ccccn1 +CCN(CC)C(=O)c1cccc(-c2c(C)n[nH]c2COC)c1 +Cc1cc(C(C)(C)C)cc(C)c1COC(=O)Cn1ccc(=O)[nH]c1=O +CNC(=O)CSc1nc(=O)n(CCCO)c2c1CCCC2 +Cc1cc2ncn(CC(O)Cn3cc(Cl)cn3)c2cc1C +CCN(CC)S(=O)(=O)c1ccc(NCc2nncn2C)cc1 +Cn1nc2n(c1=O)CCN(CCS(=O)(=O)c1ccc(C#N)cc1)C2 +Cc1ccc(-c2cc(CO)nn2CCCC#N)cc1 +Cc1ccc(C(=O)NCc2ccc(OC(F)F)cc2)o1 +O=C(Nc1ccnc2ccc(F)cc12)c1ccccc1 +CCCC(C)C(=O)C(C#N)c1nc2ccccc2s1 +CC(Sc1ncnc2sccc12)C(=O)NCc1cccs1 +O=C(c1ccnc2c1OCO2)N1CCN(C(=O)C2CCC2)CC1 +Cc1ccc(C)c(NC(=O)c2ccc(S(=O)(=O)NC(C)C)cc2)c1 +NC(=O)c1ccc(NC(=O)COC(=O)c2ccccc2Cl)cc1 +CCOc1ccc(-c2nc(C(=O)N3CC(C)OC(C)C3)cs2)cc1 +CCCCC1CCC(NS(=O)(=O)c2cn[nH]c2)CC1 +CCCn1nc(-c2ccccc2OCC)cc(C(C)=O)c1=O +O=C(Cc1csc(-c2ccccn2)n1)NCCc1ccccc1F +Nc1c(Cl)cnn1C(c1cccs1)C1CC1 +CN(c1cccc2ncccc12)S(=O)(=O)c1ccc(F)c(F)c1 +CC(C)C(Sc1nnc(-c2ccco2)n1N)C(=O)NC(C)(C)C +CN(C(=O)c1ccccc1F)C1CCc2ccccc21 +Cc1ccc(N(Cc2ccco2)C(=O)c2cc[nH]n2)cc1 +CCNC(=O)Nc1cccc(N2CCCCC2=O)c1 +COC(=O)N1CCC(NC(=O)NCCc2ccc(F)cc2)CC1 +Cc1nnsc1C(=O)Nc1sccc1C(N)=O +O=C(Nc1c[nH]cc(Br)c1=O)c1ccon1 +COc1c(NC(=O)N(C)CCOc2ccc(F)cc2)c(C)nn1C +Cc1ccc(F)cc1NC(=O)N1CCCC1c1c(C)n[nH]c1C +O=C(Nc1cccc(Cl)c1)NC1CCOC2(CCOCC2)C1 +COCCCNC(=O)c1cnc(N2CCOCC2)nc1 +N#Cc1ccc(C(=O)N2CCC(CCOCC3CC3)CC2)cc1 +N#Cc1ccc(NC(=O)Nc2ccc(C#N)cc2)cc1 +CCOC(C)C1(O)Nc2nc3nc[nH]c3c(=O)n2C1O +O=C(CN1CCOC(Cn2cncn2)C1)N1CCc2sccc2C1 +Cc1cc(N2CCCC(OCc3cccnc3)C2)nc(N)n1 +COC(=O)c1cc(OC)c(OC)cc1NC(=O)c1ccc(OC)cc1 +COc1cc(-c2cc(C)n[nH]c2=O)cc(OC)c1OC +O=C(COc1ccccc1)Nc1ccc(N2CCCS2(=O)=O)cc1 +COCCN(Cc1ccc(C#N)cc1)C(=O)c1ccncc1 +C#CCOc1ccc(C(=O)Nc2ccc(OCC)cc2)cc1 +CCOC(=O)Nc1ccc(NC(=O)c2cc(C(C)=O)c[nH]2)cc1 +Cc1noc(C2CN(C(=O)C3CCC3)CC23CCOCC3)n1 +Cc1cc(NC(=O)CCC(=O)c2ccc(Br)cc2)ccn1 +O=C(NCc1ccco1)C1CCCN1C(=O)c1cccc2[nH]ccc12 +Cc1ccc2c(NC(=O)c3ccc4c(c3)OCO4)cccc2n1 +O=C(Nc1ncccn1)c1cccc(S(=O)(=O)N2CCOCC2)c1 +Cc1cccc(-n2nc(CC(C)C)nc2C(C)NS(C)(=O)=O)c1 +CC1CCCCN1C(=O)Cn1ncc2c([nH]c3ccccc32)c1=O +O=C(Nc1cccc(-c2cn3ccsc3n2)c1)c1cccnc1 +COc1cccc(C(=O)Nc2nonc2-c2cccs2)c1 +Cc1c(C(=O)OCCn2cncn2)nnn1-c1cccc2cnccc12 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)c1ccc(N(C)C)cc1 +C=CCNC(=O)c1nc(-c2ccc(N(C)C)cc2)no1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3cccc(C#N)c3)cc2)n1 +CCC(C)C(NS(=O)(=O)c1ccc(C)s1)C(N)=O +CCCn1c(=O)n(CCC(=O)Nc2cc(C)n[nH]2)c2ccccc21 +CC(C)Cn1nccc1NC(=O)c1cccc(F)c1 +Cc1cc(C(=O)c2ccccc2Br)ccn1 +OCCCCCNc1ccc(Br)cc1 +COc1cccc(-c2nc3ccc(F)cn3c2CO)c1 +NC(=O)c1ccccc1NC(=O)CSc1nncn1N +CC1CCCN(C(=O)Cc2cccc(OCC#N)c2)C1 +Fc1cccc(F)c1CNc1ccc2cn[nH]c2c1 +COc1ccc(C2CC(c3ccccc3)=Nc3ncnn32)c(OC)c1 +CCOc1ccccc1C1CCN(C(=O)c2cc(C)n[nH]2)CC1 +CC1CCN(S(=O)(=O)c2ccc(NC3CC3)nc2)CC1 +CC1C(c2ccccc2N(C)C)CCc2nc(N)nn21 +COc1ccccc1CCc1nc(CCO)c(C)o1 +O=C(c1ccccc1Cl)N1CCC(CN2CCOCC2)CC1 +Cc1nc(C)c(C(=O)N2CCCC3(CCOC3)C2)s1 +CCC(CC)C(=O)N1CCCN(C(=O)OCC(C)C)CC1 +Cc1nn(C)c(C)c1CC(=O)Nc1nnc(C2CC2)s1 +CNC(=O)c1cccc(NCC(=O)Nc2cc(C)nn2C)c1C +CCOC(=O)C1=C(CNc2ccc(C)cc2F)NC(=O)NC1C +O=C(NCC(F)(F)F)c1cccc(-n2ccnc2)c1F +CC(=O)Nc1cccc(NC(=O)c2ccc(Cl)cc2Cl)c1 +CCc1ccc(NC(=O)c2ccc(CNC(N)=O)cc2)cc1 +CC(O)CC(C)CNC(=O)Nc1ccc(C#N)c(Cl)c1 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+CN(Cc1ccncc1)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +CC(=O)Nc1ccc(CC(=O)Nc2ccnc(C)c2)cc1 +NC(=O)C1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1 +CC(Nc1nc2ccccc2c(=O)[nH]1)c1cccc(-n2cncn2)c1 +COc1ccc(C(C)COC(=O)C(C)c2c(C)noc2C)cc1 +C=CCNC(=O)N1CCC(c2nc(-c3ccccc3)no2)CC1 +CCc1ccc(CN2CCN(Cc3cc[nH]n3)CC2)s1 +CCOCc1ccccc1CNC(=O)c1ccsc1 +CC(C)NC(=O)Nc1cccc(OCCn2cccn2)c1 +CNC(C#N)c1cc(Cl)c2c(c1)OCCCO2 +C#CCN1CCN(C(=O)NCCc2cccc(C(=O)OC)c2)CC1 +Cc1cc(C)n2c(CN(C)CCN3CCOCC3)cnc2n1 +CC(=O)Nc1nnc(SCC(=O)NCc2ccccc2)s1 +Cc1nn(C)c(C)c1NC(=O)N1CCC(OCc2cccnc2)CC1 +Cc1noc(C2CCOC3CCN(C(=O)Cc4ccccn4)CC32)n1 +COc1ccc(CNC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cn1 +CCc1ccc(C(=O)Nc2ccc(OC)c(OCC(F)(F)F)c2)o1 +NC(=O)Cn1ccnc1Cc1cc(Cl)cc(Cl)c1 +Nc1c(NCc2ccco2)ncnc1Nc1ccccc1Cl +CC(O)(CNC(=O)c1cnc2ccccc2n1)C1CC1 +Cc1ccsc1C(=O)N1CCCC(N2CCNC2=O)C1 +Cc1ccc(-c2csc(C(N)=O)c2)c(-n2cccn2)c1 +COC(=O)C(NC(=O)CN(C)C(C)=O)c1ccc(Cl)c(F)c1 +CCCCN1CCS(=O)(=O)c2c(F)c(F)nc(F)c21 +CN(C)S(=O)(=O)NCc1nc2cccnc2n1C1CCCCC1 +CC(C)c1nn(-c2ccccc2)cc1CN(C)CC(F)F +CC(C)CCS(=O)(=O)c1ccccc1C(N)=O +COc1ccc2ccccc2c1CNC(C)CCN1CCOCC1 +CC(=O)Oc1cccc(NC(=O)CSc2nccn2C)c1 +CN(Cc1ccco1)C(=O)c1cc(NC(=O)c2ccco2)n(C)n1 +Cc1cc(C(=O)Nc2sc3c(c2C(N)=O)CCCCC3)n(C)n1 +Cc1ccc(-c2nnc(SC(C(=O)N(C)C)C(C)C)n2N)cc1 +CC(CN1CCOCC1)NC(=O)N1CCCC1c1ccsc1 +C#CCNC(=O)N(C)C1CCN(c2ccc(F)cc2)CC1 +CC(C)c1nnc(SCc2nc(-c3ccoc3)no2)n1C +COc1ccc(NC(=O)COc2ccc(CC#N)cc2)cc1 +CN(CCN1CCOCC1)C(=O)Nc1cccc(F)c1F +O=C(CCCc1ncc(-c2ccccc2)o1)N1CCOc2ccccc21 +CCn1c(=O)c2ccccc2n(CC(=O)N2CCc3ccccc32)c1=O +Cc1cc(C(C)NC(=O)c2cccs2)c(C)s1 +Cc1cccc2cc(CN(C)C(=O)c3ccncc3)c(=O)[nH]c12 +COC(=O)CC(NC1CC1)C(=O)c1ccc(C)cc1 +CCC(C)Oc1ccc(-c2n[nH]c(CO)c2C)cc1 +COc1cccn(Cc2nc3ccccc3n2C)c1=O +Cc1ccc2nc(C)c(C(=O)N(C)Cc3ccc(F)cc3)n2c1 +C=CCn1c(SCC(=O)Nc2c(C)n[nH]c2C)nc2ccccc21 +CCOc1ccc(Oc2ccc(S(=O)(=O)N3CCCC3)cn2)cc1 +Cc1nc(C)c(CC(=O)Nc2nnc(C(C)C)s2)s1 +COc1ccc(CN(C)C(=O)CNc2cc(C#N)ccc2Cl)cc1 +O=C(NCCCC(=O)N1CCc2cc(F)ccc2C1)c1ccsc1 +Cn1c(CN2CCOC(C)(C(N)=O)C2)nc2ccccc21 +CC(C)(C)OC(=O)N1CCC(N2C(=O)COc3ccccc32)CC1 +O=C(NCC(=O)N1CCCc2ccccc21)C1CC=CCC1 +COCCCNc1ncnc2sc(C(=O)N(C)C)c(C)c12 +Cc1noc(C)c1CC(=O)Nc1nc(-c2ccc(F)c(F)c2)cs1 +COCCNC(=O)N(C)Cc1cccc(Cl)c1 +Nc1cc(C(=O)NC2CCCCC2)ccc1Br +N#CC1(COC(=O)c2c[nH]nc2-c2ccc(F)cc2)CCOCC1 +CC(CNC(=O)c1cccnc1)OC(=O)c1scnc1C1CC1 +O=C(c1cnn(Cc2ccccc2)c1)N1CC2CC=CCC2C1 +Cc1noc(C)c1NC(=O)NC(C)c1ccc(-n2cccn2)cc1 +CCCn1nnnc1Cn1nnc2ccccc2c1=O +O=C1CCC(C(=O)Nc2cc(Cl)ccc2OCC(F)(F)F)N1 +O=C(CCn1ncc2ccccc21)NCc1ccc(F)cc1 +CC1(NC(=O)COc2ccc3c(c2)OCO3)CCC1 +CCOc1cc(C)ccc1NC(=O)N(C)C(C)CC#N +CC(C)NC(=O)CCNC(=O)NCCc1cccc2ccccc12 +Cc1ccc(CN2CCOC3C(OCC(=O)N(C)C)CCC32)s1 +CC(CO)(NC(=O)Nc1cc(-c2ccco2)ccc1F)C1CC1 +COc1ccc2c(c1)c1nc3n(c(=O)c1n2CC(N)=O)CCS3 +CC(=O)Nc1nc(CSc2n[nH]c(=O)n2C2CC2)cs1 +COc1ccccc1CNc1nc(N)nc2c1nc(C)n2C +COc1ccc(C(=O)OC(C)C(=O)NC2CCCC2)c(F)c1 +CCCc1c(C)nn(C(=O)c2cc(OC)c(OC)c(OC)c2)c1C +CCc1nc(CN2CCN(C(=O)C(CC)CC)CC2)no1 +CCCn1c(C)nnc1SCC(=O)NCc1cccnc1 +Cc1noc(COC(=O)CCc2nc(C(C)(C)C)no2)n1 +CNS(=O)(=O)c1ccc(C(=O)Nc2ccccc2Cl)o1 +C=CCOc1ccc2c(C)cc(=O)oc2c1C(=O)CC +CNS(=O)(=O)c1cccc(CNC(=O)c2cccnc2OC)c1 +COCCSc1ccccc1C(=O)N1CCCCC1 +COC(=O)N(C)CC(=O)NC1CCCCC1C(C)(C)C +CCOc1ccc(NC(=O)c2cnn(-c3ccncc3)c2C)c(C)c1 +c1ccc(Cn2ccc(CN3CCOCC3C3CC3)c2)cc1 +CC(=O)Nc1cccc(CNC(=O)c2c[nH]c3cccc(F)c23)c1 +CNC(=O)c1cccc(NCC(=O)NCc2ccccc2C)c1C +CC(=O)NC1CCN(c2nc(C)nc3c2c(C)nn3C)C1 +COCCN1CCN(C(=O)CCn2cnc3ccccc32)CC1=O +O=C1NC(Cc2cnc[nH]2)C(=O)NC1Cc1ccccc1 +COCc1cc(C(=O)N(C)CCOc2ccccc2F)ccc1F +Cc1ccc(C(=O)NC(CC(=O)NCC(N)=O)c2ccccc2)cc1 +COCc1nc2nccc(-c3ccc(-c4ccccc4)cc3)n2n1 +CC(=O)c1c(C)[nH]c(C(=O)OCc2nc(C(C)(C)C)no2)c1C +Nc1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc21 +O=c1[nH]c2ccccc2n1CCOc1ccccc1F +Cc1ccc(CN(C(=O)CNC(=O)Cc2ccccc2)C(C)C)o1 +NC(=O)CSc1nccn1-c1ccccc1F +O=C(CSc1ccncc1)OCCC(F)(F)F +CCCC1CN(C(=O)c2cccnc2NC)CC1NS(C)(=O)=O +CC1CCCCN1C(=O)CCNc1ncc(Br)cn1 +CC(C)(C)NC(=O)C1CC(=O)N(Cc2ccccc2)C1 +C#CCOC1C(CO)OC(n2cnc3c(N)ncnc32)C1O +Cc1ccc(S(=O)(=O)NCCC(=O)Nc2cc(C)on2)cc1 +CC(C)CNC(=O)c1cc2cc(N(C)S(C)(=O)=O)ccc2s1 +Cn1ncc2c(=O)[nH]c(NCC(O)c3ccc(Cl)cc3)nc21 +COc1ccc(-c2ccnc3c(Br)c(C)nn23)cc1 +COC(C(=O)N1CCC(=O)N(CC2CC2)CC1)c1ccccc1 +COc1ccccc1NC(=O)Cn1nc2c(cc1=O)CCCC2 +O=C(CSc1ncn[nH]1)NCC1(c2ccccc2)CCCC1 +CCOC(=O)c1cnn(-c2ccncc2)c1C(F)F +CCS(=O)(=O)c1nnc(-c2ccccc2C)n1C +N#Cc1ccc(F)c(C2NCCc3c(F)cc(O)cc32)c1 +c1ccc(C2CN(c3nccnc3N3CCCC3)C2)nc1 +Cc1noc(C)c1COc1ccc(F)c2c1C(=O)CC2C +CCN(CCC#N)C(=O)CSc1nccn1-c1ccc(C)cc1C +Fc1ccc(F)c2c1CCNC2C1Cc2ccccc2N1 +CCC(C)C(=O)NCc1nc(C(=O)N2CCCC2)c(C)o1 +CNC(=O)C1CCN(C(=O)c2cc(C)n(C(C)(C)C)n2)CC1 +O=C1CN(CCSc2ccccc2F)CCN1 +CCc1cc(CNC(=O)NC2CCN(c3ccc(F)cc3F)C2)[nH]n1 +Nc1cc(S(=O)(=O)N2CCCCC2)ccc1N1CCOCC1 +Cc1ccccc1C(C)NC(=O)c1cnc(C2CCCO2)s1 +O=C1CN(C(=O)c2csc3nc(-c4ccccc4)cn23)CCN1 +COc1ccc(O)c(C(=O)N(Cc2ccccc2OC)C2CC2)c1 +Cc1ccc(C#N)cc1NC(=O)c1c(C)nn(C)c1C +CC(=O)Nc1ccc(S(=O)(=O)Cc2cc(C)ccc2C)cc1 +CCn1ccc(NC(=O)c2cc3c(OC)cccc3n2C)n1 +CCC(Cc1ccccc1)N(C)Cc1ccc(S(C)=O)cc1 +CCOCCCNC(=O)NS(=O)(=O)c1ccc(C)cc1 +CC(C)(C)OC(=O)N1CCN(C2CCCCC2=O)CC1 +CCS(=O)(=O)N1CCC(NC(=O)CCc2ccccc2F)CC1 +CCCC1CN(C(=O)Cc2c(C)nn(C(F)F)c2C)CCO1 +CC(O)C1CCN(C(=O)Nc2ccc3c(c2)COC3)CC1 +Oc1cc(O)c(C(O)(C(F)(F)F)C(F)(F)F)c(O)c1 +COc1ccc(C(C)=O)c(OC(C)C(=O)NC(C)C)c1 +COc1ccccc1OCC(=O)Nc1ccccc1O +CCCC1CN(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)CCO1 +Cn1cccc(NC(=O)c2cc(-c3cccs3)n[nH]2)c1=O +Cc1cc(C(=O)N(C)C2CCCc3ccccc32)c(C)o1 +CC(=O)c1cccc(OC(C)C(=O)NC2CCCCC2C)c1 +COc1cccc(CCNc2ncc(C(N)=O)cc2Cl)c1OC +COc1ccc(-c2n[nH]c(C)c2NC(=O)C2CCCC2)cc1OC +Cc1ccc(OCCC(=O)N2CCCC(c3nncn3C)C2)c(C)c1 +Cc1ccnc2nc(C(=O)Nc3nc4ccc(Cl)cc4s3)nn12 +COCCCNC(=O)Cc1coc2cc(C)ccc12 +CC(O)CNC(=O)c1nc(COc2ccc3c(c2)OCO3)no1 +CN(C)c1ccc(C(=O)N2CCCC(C(=O)NCC3CC3)C2)cn1 +COCc1nc(C2CCOC2)nn1-c1nc2ccccc2s1 +CC(C)n1nc(-c2ccncc2)nc1CC(F)(F)F +Cn1c(SCCCCC(N)=O)nnc1-c1ccco1 +Nc1ccccc1N1CCN(C(=O)Nc2ccccc2)CC1 +Cn1ncc2c(Nc3cccc(Cn4cncn4)c3)ncnc21 +Cc1cc(C(=O)N2CC(C)OC(C)C2)c(C)n1Cc1ccco1 +O=S1(=O)N=C(NC(c2ccccc2)c2ccccc2)c2ccccc21 +Cc1cccc(N(CCO)C2=NS(=O)(=O)c3ccccc32)c1 +Cc1cc(NC(=O)C(C)Sc2nc(C)cc(N)n2)on1 +CCCC(C#N)NC(=O)CNC(=O)CC(C)(C)C +CNS(=O)(=O)c1cc(C(=O)NC(C)c2ccncc2)cc(C)c1C +Cc1cnn(CC(C)Nc2c(C#N)c(=O)n(C)c(=O)n2C)c1 +COC(=O)c1ncn(Cc2nc(-c3cccs3)no2)n1 +CC1CCN(C(=O)C(C#N)Cc2cccc(Cl)c2)CC1 +COc1ccc(C(=O)CN2CCOCC2)c(OC)c1 +CCCOCc1ccccc1CNC(=O)c1ccc(C)nc1 +CCOc1cc(CNc2c(C)nn(CC)c2C)ccc1OC +Cc1nc(SCC(=O)C(C)(C)C)sc1CC(N)=O +COc1ccccc1C1CN(C(=O)CO)CCN1C(C)=O +CCc1cc(NC(=O)NCCc2nc3ccccc3s2)n(C)n1 +O=C(NCC1CCCO1)C1CC(=O)N(c2ccccc2)C1 +NC(=O)c1ccc(NCc2cc(F)cc(F)c2)cc1 +CC(C)N(CC(N)=O)S(=O)(=O)c1ccc(C2CCCCC2)cc1 +Cc1cnc(C(=O)OCC(=O)Nc2c(C)cccc2C)cn1 +CCNC(=O)Cc1cccc(N(Cc2ccccc2)C(=O)C2CC2)c1 +Cc1ccccc1CN(C)S(=O)(=O)Cc1ccc(C#N)cc1 +C=C(C)COc1cccc(C(=O)N(CC)Cc2noc(C)n2)c1 +O=C(NCc1ncc[nH]1)Nc1ccc(NC(=O)C2CCCO2)cc1 +O=C(COc1ccccc1)NCCCn1ncc2c(Cl)cccc21 +O=C(Nc1ccc(Br)cn1)c1cc2ccccc2oc1=O +COCCCC(=O)Nc1ccc(CNC(N)=O)cc1 +CS(=O)(=O)c1ccc2ccn(OCc3nc4ccccc4[nH]3)c2c1 +Cc1noc(C)c1C(C)C(=O)Nc1cccc(Oc2cnccn2)c1 +CC(NC(=O)NCCCN(C)S(C)(=O)=O)c1ccc(Cl)cc1 +NS(=O)(=O)CCNC(=O)CC1CCC(c2ccccc2)CC1 +O=C(NCc1ccccc1Br)C1CCOC1 +NC(=O)c1cnc(NC(=O)c2ccc(SC(F)F)cc2)s1 +Cc1ccccc1CN1CCN(Cc2cncs2)CC1 +COC(=O)CN(C)C(=O)c1ccc(Br)cc1F +N#Cc1ccc(C(=O)NCCOc2ccc3c(c2)OCO3)cc1 +O=C(Nc1nnc(C2CC2)s1)c1ccc(Cl)cc1O +CN(CCC(F)(F)F)C(=O)c1ccc(OCC(F)(F)F)nc1 +C=CCNC(=O)N(CCc1cccs1)Cc1ccoc1 +COCC(NC(=O)C(C)Oc1cccc(Cl)c1Cl)C(N)=O +Fc1cc(CNc2cnn(CC(F)F)c2)cc(F)c1F +CC(NC(=O)c1ccc(F)cc1)C(=O)N1CCOCC1 +Cc1cc2c(nc1C)oc1c(=O)n(CC(=O)Nc3ccccc3)cnc12 +CC(C(=O)OCCNc1cccnn1)c1ccccc1F +O=C(Nc1cc(CO)ccn1)c1ccc(F)c(F)c1 +Cc1cc(C)n(CCCNC(=O)c2ccc(NC(=O)C3CC3)cc2)n1 +COC(=O)C(CNC(=O)c1cccc(C)n1)Oc1ccc(F)cc1 +C=CCCCN(C)C(=O)Nc1ccc(F)c(C(=O)NC)c1 +Cc1csc(N2CCN(CCS(=O)c3ccccc3)CC2C)n1 +Cn1ccc(NC(=O)c2ccc3c(c2)NC(=O)CCS3)n1 +COCCOCc1cc(C(=O)Nc2ccc3c(c2)COC3)ccc1F +COc1cccc(-c2nnc(SCC#N)n2C)c1 +Cc1ccc(F)c(NC(=O)NCc2nnc3ccccn23)c1 +O=C(CC(c1ccccc1)c1ccccc1)NCC(O)c1ccoc1 +O=c1c(O)c(-c2ccccc2)oc2cc(O)ccc12 +Cn1c(=O)c2c(ncn2CC(=O)NCc2ccsc2)n(C)c1=O +CCn1c(CCNC(=O)Cc2ccccc2OC)nc2cccnc21 +O=S(=O)(c1ccccc1)N(Cc1cccc(F)c1)CC1CCCO1 +CN(CC(=O)N1CCOCC1)c1nc2ccccc2s1 +Cc1cc(Oc2ncccn2)ccc1NC(=O)c1csnn1 +Cc1cc2c(SC(C)C(=O)NC(C)(C)C)ncnc2s1 +CS(=O)(=O)c1cccc(C(=O)Nc2ccc3ccccc3n2)c1 +Cn1cc2ccc(F)c(C(N)c3ccncc3)c2n1 +O=C(NCCSc1cn[nH]n1)c1cc2ccccc2s1 +CCN(Cc1ccoc1)C(=O)c1ccccc1-n1ccnn1 +CNS(=O)(=O)c1cccc(C(=O)OC(C)C(=O)OC)c1 +CCOc1ccc(Nc2ncnc(NC(C)(C)C)c2N)cc1 +Cc1ccc(-c2nc(C(=O)NCC(=O)NC3CC3)cs2)cc1 +COc1ccc(C(=O)Nc2cc(C)nn2C)cc1N +COC(=O)C(C)n1nnc(-c2nc(-c3ccccc3)no2)c1N +O=C(c1ccc(Oc2cccnc2)cc1)N1CCCC1CO +Cc1ccc(NC(=O)c2cc(-c3ccccn3)nc3ccccc23)nc1 +O=C(c1ccoc1)N1CCC(Oc2cc(N3CCCCC3)ncn2)C1 +Cc1noc(C)c1C(=O)N1CCN(CC(=O)N2CCCCC2)CC1 +O=C(Nc1ccc2oc(=O)ccc2c1)N1CCOCC1 +CN(C(=O)Cn1nc2ccccn2c1=O)c1nc2ccccc2s1 +Cc1ncc(C(=O)N2CCCC2c2cnn(C)c2)s1 +CN(C)C(=O)N1CCC(C(=O)NCc2ccnn2C)CC1 +O=C1c2cnc(N3CCCC3)nc2CN1c1ccc(F)cc1 +CCCNC(=O)Cn1c(=O)c(=O)n(CC)c2ccccc21 +COCCc1noc(N)c1-c1cccc(Br)c1 +CCc1nnc(CNc2cccc(OCC(=O)N(C)C)c2)o1 +CCOC(=O)C1CCN(C(=O)c2ccc(Br)cc2)CC1 +CCC(=O)NCC(=O)NCc1noc(-c2cccs2)n1 +Cc1c(N)cccc1NC(=O)COc1ccccc1Cl +Cc1cc(C)n2nc(C)c(C(=O)Nc3nc(C4CC4)cs3)c2n1 +CN1CC2CC(C(=O)NCc3ccccc3)C(C1)O2 +CC(C)c1nnc(NC(=O)NCCNC(=O)C2CC2)s1 +Cc1occc1C(=O)NCCOc1ccc2c(c1)OCO2 +O=c1cc(CNCCCn2cncn2)[nH]c2c(Cl)cccc12 +COc1ccccc1NC(=O)CNc1c(C)cccc1C(C)C +CC(C)(C)c1ncsc1NC(=O)Nc1ccc2c(c1)CC(=O)N2 +Clc1cnn(Cc2noc(-c3ccccc3Cl)n2)c1 +COCC(=O)N1CCN(CC(O)C(C)(C)C)CC1 +NC(=O)CN(Cc1nc2cc(Cl)ccc2c(=O)[nH]1)C1CCCC1 +CC(=O)c1cccc(OC(C)C(=O)NCc2nc(C)sc2C)c1 +NC(=O)N1CCCC(NC(=O)Nc2cccc3cnccc23)C1 +COc1ccc(OC)c(CNC(=O)c2cc(C3CC3)on2)c1 +Cc1ccc(NC(=O)NCCC(F)(F)F)cc1S(C)(=O)=O +COc1ccc(-c2csc(NC(=O)NC3CCC(O)CC3)n2)cc1 +Nc1ccc(SCC(=O)c2ccc(F)cc2)cc1 +Cc1ccc(S(=O)(=O)N2CCOC(C)(C)C2)c(Cl)c1 +COc1cc(C(=O)Oc2ccc3c(c2)OCO3)cc(OC)c1OC +Cc1cc(S(C)(=O)=O)ccc1NCc1cc(=O)n2ccccc2n1 +CCN(CCO)c1ncnc2sc3c(c12)CCC3 +CCOC(=O)c1ccc(OC(=O)c2cccs2)c(OC)c1 +C#Cc1cccc(NC(=O)c2ccc(=O)n(C)n2)c1 +CC(C)(CNC(=O)NCCc1ccccc1)C(N)=O +CCC1CC(C(=O)Nc2ccnn2Cc2ccsc2)CCO1 +CNc1ccc(C2CN(Cc3noc(C)n3)CCO2)nc1 +O=C(CCC1NC(=O)c2ccccc2N=C1O)Nc1ccc(F)cc1 +CCc1nc(COC(=O)c2sc3nc(C)[nH]c(=O)c3c2C)cs1 +Cc1cccc(C)c1NC(=O)CNCc1ccc(Cl)cc1 +O=C(NCc1ccc(F)cc1)c1noc(-c2ccn3ccnc3c2)n1 +O=C(NC1CCCC1)C1CC(=O)N(Cc2ccco2)C1 +Cn1c(=O)c2c(ncn2CC(=O)C2=NC=CC2)n(C)c1=O +O=C(Cn1ccc(=O)[nH]c1=O)NCCc1nc2ccccc2[nH]1 +CCC(=O)N1CCCC(C(=O)Nc2cc(F)ccc2OC)C1 +CC(C)=CC(=O)OCCn1c(=O)oc2ccccc21 +C=CCNc1nc2c(c(=O)[nH]c(=O)n2C)n1CC(=O)OC +COc1ccc(-c2cc(N)nc(C)n2)cc1NC(C)=O +COc1cc2c(cc1OC)C(C)N(C(=O)c1cccc(Cl)c1)CC2 +CC(C)c1cc(C2CCCN2C(=O)c2ccn(C)n2)no1 +COc1ccc(-n2ccnc2SCC(=O)Nc2cccnc2)cc1 +COc1cc(C(=O)N(C)Cc2cccs2)cc2occc12 +COc1ccc(O)c(C(=O)N2CCN(c3nccs3)CC2)c1 +Cc1cc(Br)c(S(=O)(=O)NCCO)cc1Cl +O=C(CNc1cccc(OCC2CCCO2)c1)Nc1ccccc1F +Cc1cc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)on1 +CCN(Cc1nc(C)no1)C(=O)Nc1ccc(F)c(C)c1 +COc1cccc(C(=O)Nn2cnc3c(cnn3C(C)(C)C)c2=O)c1 +CCC(C)(C(=O)NCc1ccc(C(F)(F)F)cc1)N1CCC1=O +O=C(CS(=O)(=O)c1ccccc1)NCCc1ccc(F)cc1 +CCC(OC(=O)Cc1c(C)nc(C)[nH]c1=O)c1ccc(C)cc1 +O=C(NC(Cc1ccccc1)C1CC1)c1ccc(-c2ccco2)[nH]c1=O +O=S(=O)(Nc1cn[nH]c1)c1ccc(F)cc1Br +CC(C)S(=O)(=O)N1CCN(S(=O)(=O)N(C)C)CC1 +CN(CC(=O)NCCOc1cccc(F)c1)S(C)(=O)=O +CN(C)C1CCN(c2nc3sccn3c2CO)CC1 +CC(C)OCc1c(C(=O)NCc2n[nH]c(=O)[nH]2)oc2ccccc12 +Cc1noc(CCCC(=O)Nc2ccccc2C(=O)NC(C)(C)C)n1 +Cc1ccc(-c2oncc2C(=O)NCc2ccco2)cc1 +CCOc1ccc(Cl)c(C(=O)NCc2cccc(COC)c2)n1 +CNC(=O)CNC(=O)CNC(=O)c1ccc(Cl)cc1Cl +Cc1nnc(C2CC3OCCC3N(c3ncccn3)C2)o1 +CC(Oc1ccc(-n2cnnn2)cc1)c1nc(-c2ccccc2)no1 +NC(=O)Cc1ccc(OCC(=O)Nc2ccccc2F)cc1 +CNC(=O)Cn1c(-c2ccco2)nn(-c2ccccc2OC)c1=O +Cc1cc(NC(=O)C(C)C)ccc1Oc1cccnc1 +COc1cc2[nH]c(C)c(C(C)C)c(=O)c2cc1OC +Nc1cc(C(F)(F)F)ccc1NCC1CCCO1 +COc1ccc(-c2noc(NCC3COc4ccccc4O3)n2)cc1 +CCN(CC(=O)NC(C)C)C(=O)c1cccc(Br)c1 +CC(=O)c1c(O)cc2cccc3c2c1CC(C)(O)O3 +O=C(Nc1ccc(F)cc1)N1CCN(C(=O)C2CC2)CC1 +CCOc1cc(C)ccc1NC(=O)N1CCC12CCC2 +CC(=O)NCCNC(=O)N(C)Cc1ccc(C)cc1C +O=C(NCCSc1cn[nH]n1)c1nc2c(s1)CCCC2 +Cc1ccc(Oc2cc(-n3ncc(C#N)c3N)ncn2)cc1 +O=C(NCc1cccs1)c1ccc(Br)c(F)c1 +O=C(CCn1ncc2c(Cl)cccc21)NCc1ccc(F)cc1 +CCN(CC1CCOC1)C(=O)c1cccnc1N1CCOCC1 +N#Cc1cc(F)c(NCC2CCN(CC(F)(F)F)C2)c(F)c1 +Cc1ccc(C(=O)Nc2cccc(C(=O)N(C)C)c2)s1 +Cc1cc(C)n(C(C)C(=O)Nc2cc(Cl)c(Cl)cn2)n1 +CCCCC(=O)N1CCC(n2ncc(C(=O)OCC)c2N)CC1 +Cc1cccc(C(=O)N2CC(NS(C)(=O)=O)C3OCCCC32)n1 +CCOc1ccccc1C(=O)Nc1ncc(C#N)s1 +CCC1C(=O)Nc2c1cc(F)cc2C(O)c1ccccc1C +Cc1cc(CSc2nnc(C)n2CCc2cccs2)on1 +CC(C)c1nnc(NC(=O)COCc2ccccc2Cl)s1 +CCC1CCCC(NC(=O)CNC(=O)c2ccc(OC)cc2)C1 +COC(=O)CCCc1nnc(NC(=O)C2CC=CC2)s1 +O=C(Nc1cccc(C(F)(F)F)c1)N1CCOCC1 +Cn1nnc2c1C(COCC1CC1)CN(C(=O)c1cccc(F)c1)C2 +Cc1ccc(S(=O)(=O)N2Cc3ccccc3CC2C(N)=O)c(C)c1 +CCc1ccc(C(C)NCC(=O)N(C)C2CC2)cc1 +Cn1cc(CC2C(O)CCN2C(=O)c2ccc3[nH]ccc3c2)cn1 +CC1Cc2ccccc2N1CCCNS(C)(=O)=O +O=C(CN1CCN(c2cccnc2)CC1)N1CCc2ccccc2C1 +O=C(NCCCn1ccnc1-c1ccccc1)c1cccs1 +COc1cc(C(=O)Nc2noc3nc(C)ccc23)cc(OC)c1OC +Cc1nn(C)c(C)c1CCC(=O)OCCC(C)C +CCc1ccc2oc3c(c(=O)c2c1)C(c1ccncc1)N(C)C3=O +Nc1cc(N2CCC(CO)(CCCc3ccccc3)CC2)nc(N)n1 +CCOC(=O)c1c(N)c(=O)n2c3c(cccc13)CC2 +COCc1nn(Cc2c(F)cccc2Br)c(=O)o1 +O=C(c1ccc(F)cc1F)n1nnc2ccccc21 +C=CCN1CCN(C(=O)c2c(Cl)cnn2C)CC1 +Cc1csc(CNc2c(F)cc(F)cc2F)n1 +CCC(C)NC(=O)c1cc(C)ccc1NC(=O)N(C)C +COc1cccc2cc(C(=O)N3CCCC3c3ccncc3)oc12 +COc1cccc(CCNC(=O)Nc2cn[nH]c2)c1 +Cc1cc(C)n(Cc2ccc(C(=O)OCCn3cncn3)cc2)n1 +Cc1ccc(NC(=O)C2CCOc3ccccc32)cc1C(=O)N(C)C +Cc1ccc(O)c(NC(=O)C2CCCN2C(=O)Cc2cccs2)c1 +Cc1cc2c(=O)n(CC(=O)N3CCCCC3C(N)=O)cnc2s1 +Cc1cc(CNC(=O)Nc2ccc(OC3CCC3)c(F)c2)no1 +Cc1ncsc1C(=O)NCCOc1cccc2c1OC(C)(C)C2 +COc1ccc(C(=O)Nc2nnc(-c3cccc(C)c3)o2)cc1OC +CC1CCc2nc(NC(=O)Cc3ccc4c(c3)OCCO4)sc2C1 +CC1CCc2nc(N)c(C#N)c(-c3ccco3)c2C1 +COc1ccc(NC(=O)Cc2c(C)noc2C)c(OC)c1 +CCCNC(=O)Cn1c(=O)n(C2CCCC2)c2ncccc21 +Cc1cccc(NCCC(O)c2ccc3c(c2)OCCO3)c1C +Cc1nc(NC(=O)Cc2ccc(Cl)cc2)sc1C(=O)N(C)C +Nc1cccc(NC(=O)N(CCO)C2CCCC2)c1 +CCN(Cc1cccs1)C(=O)NC1CCCCNC1=O +CN(C(=O)CSc1nc(-c2cccs2)n[nH]1)c1ccccc1 +COc1ccc(F)cc1NC(=O)CNC(=O)Cc1cccc(F)c1 +CCCn1nccc1C(=O)Nc1cnn(CC2CC2)c1 +C#CCN1C(=O)CSc2nnc(COc3ccccc3Cl)n21 +CCCCN(C)S(=O)(=O)NC1CCCCC1C +Cc1csc(NC(=O)CN2CCOC(Cn3cccn3)C2)n1 +CC(=O)N1CCN(C(=O)c2cc(N3CCCC3=O)ccc2Cl)CC1 +Cn1ncc2c(NCCc3cccc(F)c3)nc(-c3ccncc3)nc21 +CCOC(=O)C12CCCN(C(=O)c3ccco3)CC1CN(C(C)=O)C2 +CCC(=O)N(Cc1ccc(OCC2CCC2)cc1)C1CC1 +O=C(Nc1ccc(-c2csnn2)cc1)c1cccnc1-n1cccn1 +CN(C)C(=O)c1ccc(-c2cc(C(F)(F)F)nn2C)s1 +Cc1ccc(-n2c(SCC(N)=O)nc3ccccc3c2=O)cc1 +Cn1ccnc1SCCNC(=O)c1cnc(-c2cccnc2)nc1 +CCCN1CCc2nc(NC(=O)c3ccc(C(C)=O)cc3)sc2C1 +CC(C)OCCC(=O)NC(C)c1nnc2ccccn12 +CCC1=C(C(=O)OC(C)C)C(c2ccc(C)o2)NC(=O)N1 +CN(Cc1ccccc1)C(=O)Nc1cn(C)c2ccccc12 +Cc1ccc(OCCNC(=O)c2ccc(C)o2)cc1 +O=C(c1ccc2nccnc2c1)N1CCCCC1c1cccc(F)c1 +Cc1nn(C)c2ncc(NC(=O)Cc3ccc[nH]3)cc12 +CCOc1ccc(-c2csc3nc(CO)cn23)cc1 +O=C(NCCn1ccnn1)Nc1ccccc1Oc1cccc(F)c1 +Cc1cc(C)nc(NCCC(=O)Nc2nc3c(s2)CCC3)n1 +COc1ccccc1N1CCN(C(=O)NCc2nc(C)cs2)CC1 +CN(C)C(=O)c1csc(NC(=O)c2ccccc2F)n1 +CN(C)c1nc(N)nc(COc2c(Cl)cccc2Cl)n1 +O=C(Cc1c(F)cccc1F)NCc1csc(=O)[nH]1 +Cc1ccccc1NC(=O)c1nccc2cccc(N)c12 +Cc1cc(N)c2oc(-c3cncc(Br)c3)nc2c1 +CC1(C)CCCN1C(=O)CCCNC(=O)c1ccc(F)cc1F +O=C(Nc1cccc2ncccc12)c1cn2cc(Cl)ccc2n1 +CC(=O)c1ccccc1NCC(=O)Nc1ccc(OC(F)F)cc1 +COc1cc(NC(=O)NC(C)c2nc3ccccc3[nH]2)cc(OC)c1 +Cc1cc(N)nc(SCC(=O)NC(c2cccs2)C(C)C)n1 +COc1ccc(NC(=O)C2(c3ccccc3)CCOCC2)c(OC)c1 +Cc1ccc(NC(=O)c2sc(-c3ccc(C)o3)nc2C)nc1 +CCC(C)Nc1nc(-c2c3c(n[nH]c2=O)CCC3)cs1 +CCN(Cc1nc2cc(Cl)ccc2c(=O)[nH]1)C(=O)c1cc(C)no1 +Cc1ccsc1CN(C)S(=O)(=O)c1cn[nH]c1C +Cc1cc(F)ccc1C(=O)NCc1nnc(C)n1C1CC1 +Cc1cc(C)c(NC(=O)CNc2nnnn2-c2ccccc2)c(C)c1 +Cc1nc(-c2ccccc2)sc1C(=O)N(C)CC(=O)N(C)C +CC(CCCO)NC(=O)Nc1cccc(Oc2ccccn2)c1 +COCC(O)CCc1cc(Br)cs1 +O=C(Cc1cc(F)ccc1F)N1CCOc2ccc(F)cc21 +CC(=O)Nc1ccc(F)c(NC(=O)c2cccc3ccccc23)c1 +Nc1cc(Cn2ccc(=O)[nH]c2=O)ccc1Cl +Cn1ccnc1C(O)(CCNC(=O)NCc1ccco1)C(F)(F)F +COc1ccc(S(=O)(=O)CCC(=O)Nc2cccc(C#N)c2)cc1 +Clc1ccc(Cl)c(-c2noc3c2CCN3)c1 +Cc1ccccc1CC(=O)NCCc1nc2ccccc2[nH]1 +CC1CCN(C(=O)c2nc(-c3cnccn3)no2)CC1 +CCOc1ccc(NC(=O)c2c[nH]nc2-c2ccccc2F)cc1 +CS(=O)(=O)c1ccc(Cl)c(S(=O)(=O)NCc2cn[nH]c2)c1 +COC(=O)C(C)NC(=O)c1ccc(F)cc1NC(=O)CC(C)(C)C +Cc1ccc(CC(=O)Oc2ccc(F)cc2)s1 +COC(=O)c1ncn(Cc2cccc(C(=O)NCc3ccco3)c2)n1 +O=C(c1ccc(F)cc1)C1CCCN(Cc2cncs2)C1 +CSc1ncc(Cl)c(C(=O)NC(C)c2ccc(C)o2)n1 +NC(=O)Nc1ccc(C(=O)COc2cc(F)ccc2F)cc1 +CNC(=O)c1cccc(-c2ccc(C(C)N3CCOCC3)cc2)n1 +COc1ccc(CN(C(=O)c2cccc(Cl)c2)C2CC2)cc1 +CC(C)c1cc(=O)[nH]c2cc(NC(=O)C3CC3)ccc12 +Cc1nc2cccc(F)c2n1CCN1CCOCC1 +O=C(Cn1nc(-c2ccco2)ccc1=O)Nc1ccc(F)c(F)c1 +CC1CCN(S(=O)(=O)c2cccc(C(=O)N(C)C)c2)CC1 +CCc1nnc(NC(=O)c2cccc(-n3cccn3)n2)s1 +O=C(CCCOc1cccc(F)c1)Nc1ccccc1-n1cnnn1 +CC(CC#N)N(C)Cc1cc(-c2ccccc2)[nH]n1 +Cc1ccc(CN(C)C(=O)c2cccc(NS(C)(=O)=O)c2)o1 +CCCNC(=O)CNC(=O)NCC(=O)Nc1c(C)cccc1C +CC(C)(C)NC(=O)Cn1nnc(-c2ccc(Cl)cc2)n1 +CCC1CCCCC1NC(=O)NCCCc1n[nH]c(N)c1C#N +O=S(=O)(NCc1ccsc1)c1cc(F)ccc1F +CCCc1nnc(N2CCN(c3cccc(C)c3C)CC2)o1 +Cc1ccccc1-c1cnnc(N(C)CCc2nc3ccccc3[nH]2)n1 +O=C(c1cn2ccccc2n1)N1CCN(Cc2cccc(F)c2)CC1 +CC(C)C(=O)Nc1nc(-c2cccs2)cs1 +CC(C)CCCOC(=O)Cn1cc(N)ccc1=O +CNC(=O)c1sc(NCCc2ccccc2)nc1C +CN(C(=O)c1cncc(Br)c1)c1cccc(F)c1 +Cc1ccccc1SCC(=O)N1CCOCC1C1CC1 +COc1cc(N)ccc1NC(=O)CN1CCCC1=O +CCN1CCN(C(=O)c2ccnc(Oc3ccccc3)c2)CC1 +CCC(C)N(CCOC)C(=O)c1ccnc(F)c1 +O=C(COc1cccc(Oc2ncccn2)c1)NCc1ccco1 +Brc1cc(-c2ccccc2)cn2cnnc12 +O=C(NCCN1CCCS1(=O)=O)c1cccc2ccccc12 +COc1ccc(NC(=O)CN(C)C(=O)c2ccccc2)cc1C +CC(N(C)C(=O)c1c[nH]c(=O)c(Cl)c1)C(C)(C)C +CC(C)(C)c1cc(C(=O)OCCNc2cccnn2)[nH]n1 +Cc1cc(NC(=O)NC(C)c2ccc(S(N)(=O)=O)cc2)n(C)n1 +CCc1ccc(OC)c(-c2cc(C#N)c(=O)n(CC)n2)c1 +CCOC(=O)N1CCN(C(=O)c2cc(-c3ccccc3)cs2)CC1 +CCNC(=O)N1CCN(CCNC(=O)c2ccccc2F)CC1 +Cc1c(CNC(=O)Nc2nnc3ccccn23)cnn1C +COc1cccc(CNC(=O)C(C)S(=O)(=O)c2nccn2C)c1 +CNc1nc(N2CCN(CCO)CC2)nc2c1C(=O)CC(C)(C)C2 +CCCOc1ccc(C(=O)CCC(=O)N2CCC2)cc1 +COc1ccc(S(=O)(=O)NCCc2ccccc2)cc1 +O=C(CCCC(O)c1ccc(F)cc1)NC1CCCCC1 +COc1c(CNc2ccc(C(=O)NC(C)C)c(C)c2)c(C)nn1C +COCCCNC(=O)c1cnc(COC)nc1N +COCCCNC(=O)Nc1ccc(C)cc1Br +CC(=O)Nc1ccc(NC(=O)C2CC3C=CC2C3)cc1 +O=C(Cn1nnc(-c2cccs2)n1)NCc1ccco1 +CC(C)CC(=O)N1CCC(NC(=O)c2ccc(F)cc2)CC1 +COc1ccncc1NC(=O)Cc1csc(-c2ccoc2)n1 +Cc1nc(C)c(CC(=O)NC(c2ccccc2)C2CC2)c(=O)[nH]1 +CC(C)c1nc(C2CCCN(C(=O)CCCn3cncn3)C2)no1 +CC(=O)N(C)Cc1cccc(NC(=O)N2CCOCC2C2CC2)c1 +O=C(Nc1cccc2cnccc12)C1CC1c1ccccc1F +CC(C)n1ccnc1-c1nccn1CCCc1cnn(C)c1 +Cc1c(NC(=O)N2CCCCC2CO)cnn1-c1cccc(Cl)c1 +COc1ccccc1OCC(=O)NC(C)c1ccc(F)c(F)c1 +CCCN(Cc1cccnc1)C(=O)c1ccc2c(c1)ncn2CCO +CCNC(=O)c1ccc(NC(=O)NCCCc2cccc(F)c2)cc1 +Cc1ccc(NC(=O)c2cn3c(C)cccc3n2)c(Cl)c1 +O=C(Nc1ccc(C(=O)Nc2cccnc2)cc1)c1ccccc1 +CC1CCCCN1S(=O)(=O)c1ccc(N2CCOC2=O)cc1 +CCCn1nc(-c2cccc(OCC)c2)cc(C(C)=O)c1=O +CC(=O)c1cc(CC(=O)NCc2cccc(F)c2)cs1 +CCCNC(=O)c1ccc(NC(=O)c2cc(C)nn2C)cc1 +CC(C)n1ncc2cc(NC(=O)c3cc(F)ccc3F)cnc21 +COc1ccc(NC(C)=O)cc1N(CCO)CCO +CC(=O)N1CCc2cc(NC(=O)C(C)Oc3ccc(C)cc3)ccc21 +Cc1ccc(O)c2c1C(CNC(=O)OC(C)(C)C)NCC2 +CCSc1ccc(C(C)NC(=O)NCc2c(C)noc2C)cc1 +COc1ncc(Cl)c(N2CCC(c3noc(C)n3)CC2)n1 +Cc1cc(C(=O)NCCOc2c(C)cccc2C)no1 +CCC(CC)NC(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +COc1ccc(C2CC(=O)CC(Nc3nonc3N)C2)cc1OC +CN(CCOc1ccc(F)cc1)S(=O)(=O)c1cccs1 +CC1CN(C(=O)C2CC(=O)Nc3ccccc32)c2ccccc21 +Cc1ccc(CNS(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)cc1 +CCCNC(=O)C1CCCN(c2cnc3nccnc3c2)C1 +Cc1cccc(C(=O)NC2CCCN(c3ncccn3)C2)n1 +Cc1cc(C)nc(NCCOc2ccccc2N)n1 +O=C(Nc1nc(C(=O)N2CCOCC2)co1)c1ccccc1 +Cc1ccc(N2C(=O)CCC2(C)C(=O)NCCCOC(C)C)c(C)c1 +O=C1CCC(C2NCCc3cc(OC(F)F)ccc32)N1 +CCC(O)(CC)CNC(=O)NC1CCCN(Cc2ccccc2)C1=O +COc1ccc(CNc2ncnc(-n3nc(C)cc3C)c2N)cc1 +CC(=O)Oc1ccc2cc(-c3ccc4c(c3)OCCO4)c(=O)oc2c1 +CCc1ccc(S(=O)(=O)Nc2cnn(C3CCOCC3)c2)s1 +CC(C)CC(=O)N1Cc2ccccc2CC1C(=O)NCC(F)(F)F +COCCCNC(=O)N1CCN(Cc2ccc(OC)nc2)CC1 +Cc1nc(-c2cc(C(=O)N3CC(C)OC(C)C3)n(C)c2)cs1 +CCN(CC(F)(F)F)C(=O)c1ccc(F)cc1N +OCc1csc(Cc2ccc(Cl)cc2Cl)n1 +O=C1CCc2cc(S(=O)(=O)N3CCCC3)cc3c2N1CCC3 +CC(C)(C)n1cc(C(=O)OCc2ccc(-n3cccn3)cc2)cn1 +CC(C)n1nccc1NC(=O)c1csc(-c2cccs2)n1 +CC(=O)c1ccccc1NC(=O)COc1cccc2c1OC(C)(C)C2 +CN(C(=O)CCCc1cc(F)ccc1F)C1CCCc2c1cnn2C +Cc1ccc(CNC(=O)c2cc(Br)ccc2Cl)o1 +O=S(=O)(NCC1CN2CCCCC2CO1)N1CCCCCC1 +O=C(NCCc1ncc2ccccn12)NC1CCCCC1 +NS(=O)(=O)Cc1ccc(CNC(=O)c2cccnc2)cc1 +CN(CCc1ccccn1)C(=O)c1cc(=O)[nH]c2ccccc12 +Cc1nc(NCc2ccc(F)cc2)c2cc(C)sc2n1 +CCOC(=O)CSc1ccc(NC(C)=O)nn1 +CC(C)n1nccc1NC(=O)c1c[nH]c2c(F)cccc2c1=O +N#Cc1cccc2nc(-c3cncc(Br)c3)nn12 +COCCOc1nc(C)c2c(c1C#N)CC(C)(C)OC2 +Cn1cc(-c2nn3c(Cc4ccccc4)nnc3s2)cn1 +Cc1cnn(Cc2ccccc2C(F)(F)F)c1N +CCn1nc(C#N)cc1-c1c(C)cc(OC)cc1C +O=C(Nc1cc2c(cc1Cl)OCCO2)c1ccccn1 +O=C(Nc1ccnn1C1CCCC1)c1cccs1 +CCc1cc2c(N3CCCC4(C3)OCCO4)ncnc2s1 +O=C(OCC(=O)N1CCc2ccccc2C1)c1ccccc1O +CC(NC(=O)COc1ccc(Cl)cc1)C(=O)N1CCCCC1 +COc1ccc(C)nc1NC(=O)NCc1ccn(C2CCCC2)n1 +O=C(c1ccccc1Br)N1CCOCC1C1CC1 +CCc1ccc(S(=O)(=O)N(C)CCC(=O)OC)s1 +CCOC(=O)C1(O)c2ccccc2-c2ccccc21 +CC(=O)Nc1ccc(NC(=O)Cc2cn3ccsc3n2)c(Cl)c1 +COc1cccc(C(=O)OCC(=O)Nc2c(F)cccc2F)c1 +Cc1ccc(-n2nccc2NC(=O)c2scnc2C2CC2)nn1 +Cc1ncsc1CCN(C)C(=O)c1ccc(-n2cnnn2)cc1O +Cc1noc(CCC(=O)C(C#N)c2nc3ccccc3[nH]2)n1 +CC1(C)CCCN1C(=O)c1cnn(-c2ccc(Cl)cc2)c1 +CC(CO)(NC(=O)NCc1ccncc1)C1CCCCC1 +CC(C)(C)c1ccc(SCC(=O)NCC(O)c2ccco2)cc1 +Cc1ccc2c(c1C)CCNC2C(O)c1ccccc1F +COc1ccc(Cl)cc1-c1nc(-c2ccccn2)no1 +CC(C)C(=O)N1CCC2(COCc3cnc(N(C)C)nc32)C1 +O=C(NCc1csc(CCc2ccccc2)n1)c1cc[nH]n1 +CC1CN(C(=O)C2CCCN2C(=O)C(C)C)C(C)CO1 +CCCn1nc(C)c(CN2CCOC(CC(=O)OC)C2)c1C +CC(C)NC(=O)c1ccccc1NC(=O)C1CC=CC1 +CC1CCCN(C(=O)Cc2ccc(F)c(F)c2)C1 +CCCCC(COC)NC(=O)N1CCC(N(C)C(C)=O)CC1 +COc1ccc(Cn2nnnc2SC(C)C(=O)NC2CC2)cc1 +CNC(=O)c1ccc(NC(=O)CNC(=O)c2cc(C)nn2C)cc1 +O=C(Nc1ccnc2ccnn12)c1cccc(-n2cnnn2)c1 +O=C(NCCCn1cccn1)N1CCN(Cc2cccnc2)CC1 +CS(=O)(=O)c1ccc(NCC2CCCO2)c(S(C)(=O)=O)c1 +Cc1ccc(C(=O)N2CCC3(CC2)CC(c2ccccc2)C(=O)N3)o1 +COc1ccc(CC(C)CNC(=O)c2cc(C)ncn2)cc1 +Cc1cc(C)cc(NC(=O)c2cccc(N3CCCC3=O)c2)c1 +Cc1ccc(NC(=O)C(C)N2CC(C)Oc3cc(N)ccc32)cc1 +O=C(c1ccc(O)cc1)N1CCN(CCOc2ccc(F)cc2)CC1 +CCOCCn1c(C2CCCO2)nc2cc(C(F)(F)F)ccc21 +CN(C)S(=O)(=O)c1ccc(OCc2nc3ccccc3o2)cc1 +CC(C)(C)OC(=O)N1CCN(CC(=O)NCC2CCC2)CC1 +O=C(CNS(=O)(=O)c1cccc(Cl)c1)NCC(F)(F)F +CCOC(=O)CCNc1ccc(Cl)c(Cl)c1 +Clc1cccc(-c2nnc(-c3cccnc3)o2)c1 +O=C(c1ccccc1F)N1CCn2nnc(COCC3CC3)c2C1 +CC(C)C(=O)NCCn1c(=O)[nH]c2ccccc2c1=O +Cc1cnn(-c2ccccc2)c1NC(=O)CCSc1ccccn1 +CCOCCNC(=O)c1nnn(-c2ccc(F)cc2)c1C(F)(F)F +Cc1nn(C(C)(C)C)cc1C(C)NC(=O)Nc1c[nH]c(=O)c(C)c1 +CCOC(=O)c1ccccc1Nc1ncnc(OC(C)C)c1N +CCCNC(=O)CN(C)S(=O)(=O)c1cc(C)ccc1C +CNc1ccnc(N2CCOC(C(F)(F)F)C2)n1 +O=C(Cc1cccnc1)N1CCC(c2cc3cccnc3c(=O)[nH]2)CC1 +Cc1cc(NC(=O)CCc2ncc(-c3ccccc3F)o2)n(C)n1 +Cc1nc[nH]c1-c1nccn1Cc1nc2ccccc2s1 +Cc1nnc(-n2nnc(C#N)c2Cc2ccc(Cl)cc2)s1 +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)Cc1c[nH]c2ccccc12 +CC1=Nc2ncnn2C(c2ccc(OC(F)(F)F)cc2)C1C(N)=O +CCS(=O)(=O)NCCSc1nnnn1-c1cccc(F)c1 +CN(C(=O)c1ccc(OCC(F)F)nc1)c1ccccc1 +COC(=O)c1cc(-c2ccc(OC(C)C)cc2)on1 +CC(=O)c1ccc(NC(=O)C(C)NC(=O)C2CCCCC2)cc1C +O=C(NCC1CCCO1)c1ccc(COc2ccc(F)cc2F)o1 +COCCN(C(C)=O)c1nc(CSc2cccc(C)c2)cs1 +OCC1(CSc2nc3ccccc3o2)COC1 +CCOc1ccc(NC(=O)NCCC(=O)N2CCCC2)cc1 +Cc1ccc(S(=O)(=O)NC(C)Cc2ccsc2)cc1F +CC(C)Cc1cc(NC(=O)c2cc3c([nH]c2=O)CCCC3=O)n(C)n1 +CNC(=O)c1ccc(Cl)c(NC(=O)CCSc2ccccn2)c1 +Cc1ccc(-n2cc(C(=O)NCC(C)(C)c3ccncc3)nn2)cc1 +CCOC(=O)c1nn(-c2ccccc2Cl)c(=O)cc1OCC +C#CCOc1ccc(C(=O)C(C#N)c2nc(C)cc(C)n2)cc1 +CC(OCc1ccccc1)C(=O)Nc1nc(C(C)C)cs1 +O=C(NCc1ccccc1F)C1CCC(C(F)(F)F)NC1=O +CCC(C(=O)NC1CC1)N(c1ccc(OC)cc1)S(C)(=O)=O +COc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)cc1 +Cn1nnnc1Sc1cc(=O)n(C)c(=O)n1C +O=C(COC(=O)c1cnccn1)Nc1ccc2c(c1)CCC2 +Cc1ccccc1NC(=O)CCc1nc(-c2ccsc2)no1 +Cc1nc(-n2cnc(C#N)n2)c2c(-c3cccs3)csc2n1 +Cc1cccc(C(C)CNC(=O)c2ccc3c(c2)NC(=O)CO3)c1 +O=C1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CCN1 +CC(C)n1nccc1C(=O)N1CCC(c2cnccn2)CC1 +COc1ccc(C(O)CCN2CCc3ccccc32)cc1OC +CC(=O)NC(C)c1nc2ccccc2n1CCOc1ccccc1C +Cc1nc(CC(=O)Nc2sc3c(c2C#N)CCCCC3)cs1 +CC1CN(C(=O)C2CCCO2)C(c2ccccc2)CN1 +O=c1c(-c2ccc(F)cc2)coc2c3c(ccc12)OCN(CCO)C3 +Cc1noc(C2COCCN2C(=O)c2cc(Cl)cn2C)n1 +O=C1C(NC(=O)N(CCCCO)C2CC2)CCN1c1ccccc1F +Cc1ccc2c(CC(=O)NCCCCN3CCOCC3)coc2c1C +O=C(Nc1cccc2ncccc12)c1ccc(Cn2ccnc2)cc1 +CCC(C)C(=O)N1CCCN(C(=O)OCC(C)C)CC1 +COc1ccc(S(=O)(=O)N2CCN(CC(C)O)CC2)cc1 +Cc1cnc(NC(=O)c2cccc(OCC(C)C)c2)s1 +O=C(CCc1ccc(F)cc1)N1CCCC(CN2CCOCC2)C1 +CN(CC(=O)NCC(=O)NC1CC1)c1ccccc1 +CN(CC(=O)N1CC2(COC(C)(C)OC2)C1)S(C)(=O)=O +CC(C)N(CCCO)C(=O)c1cc(F)ccc1F +CC(C)c1nc(N2CCC3(O)CCCCC3C2)c2cnn(C)c2n1 +CCOC(=O)C1CCCN(C(=O)c2ccnc(OC3CCC3)c2)C1 +CS(=O)(=O)NCC1CCCN(c2ccc(C#N)cn2)C1 +NC(=O)c1cccc(OCc2nc(-c3ccncc3)no2)c1 +COc1ccc(C(=O)NCCNC(=O)c2scnc2C2CC2)cc1 +O=C1COC2(CCN(c3ncc(F)cn3)CC2)CN1c1ccsc1 +CC(NC(=O)CN(C)S(C)(=O)=O)c1ccc2c(c1)OCCCO2 +CCOC(=O)c1ccc(OCCn2c(=O)oc3cccnc32)cc1 +CCOC(=O)COC(=O)Cc1cc2ccccc2[nH]c1=O +CC(=O)c1c(C)nc(C)nc1SCC(=O)Nc1cc(C)on1 +CNS(=O)(=O)c1ccc(NC(=O)c2cc(F)ccc2OC)cc1 +O=C(Cc1csc(N2CCCC2=O)n1)Nc1nc(C2CC2)cs1 +CCCn1nc(C(=O)Nc2cc(C)nc(C(C)C)n2)ccc1=O +Cc1nn(C)c(C)c1NC(=O)CCc1nc2ccccc2[nH]1 +CC(Nc1ccc(Br)cc1)c1cccc(-n2cnnn2)c1 +Cc1ccc(-c2c3c(=O)n(C)c(=O)n(C)c3c3n2CCOC3)cc1 +Fc1ccc(Cn2ncc3c2CN(c2ncnc4[nH]cnc24)C3)cc1 +CC(C)c1cc(C(=O)N2CCC3(CC2)OCCO3)nn1C(C)(C)C +COC(=O)c1c(NC(=O)c2scnc2C2CC2)sc2c1CCC2 +Cc1ccc(C(=O)N2CCC(NC(=O)c3ccc[nH]3)CC2)cc1 +Cn1ncnc1NC(=O)NC1c2ccccc2CC1O +CC(C)Cn1ncc(C(=O)Nc2cccc3c2C(=O)NC3)c1C(F)F +O=C(NCCNC(=O)c1cncc2cnccc12)Nc1ccccc1 +CC(C)n1ncc2cc(C(=O)Oc3ccc(-c4nnco4)cc3)cnc21 +COc1ccccc1CNC(=O)c1ccc(-c2cscn2)cc1 +Cc1ccc(C)c(OC2CCN(C(=O)C(C)(C)C#N)CC2)c1 +COCC(NC(=O)c1cc(C)ccc1O)C(N)=O +CNc1nnc(SCC(O)COc2ccc(Cl)cc2)s1 +COC(=O)C1CCCCN1CC(O)COc1cc(C)ccc1C +Cn1cccc1CN1CCN(Cc2cccnc2)CC1 +CCC(=O)N1CCCN(Cc2cnc(N(CC)CC)s2)CC1 +O=S(=O)(NCc1ccc2c(c1)OCCO2)c1ccccc1Cl +Cc1ccc(C)c(C(=O)NCC2CCN(c3ncccn3)CC2)c1 +CC(C)(C)c1noc(CCCC(=O)NCCO)n1 +COC(=O)C(NC(=O)Cn1cnc(N)n1)C(C)C +COc1cc(NC(=O)NC(C)c2ccc(C)nc2)cc(OC)c1OC +Cc1ccc(OCc2cc(-c3ccc(N)cc3)n[nH]2)cc1 +CN1C(=O)CCC2(CNC(=O)c3ccc(F)cc3Cl)CCCC12 +CCC(C)NC(=O)Cc1csc(-c2ccccc2N)n1 +N#Cc1c(-c2ccc3c(c2)OCO3)cc(-c2ccc[nH]2)nc1N +COc1c(Cl)cccc1NC(=O)NCC(C)(O)c1ccco1 +O=C(CCCc1ccccc1)NCCc1ccncc1 +Cc1cc(C(=O)Nc2cccc(Cl)c2C)ccc1-n1cnnn1 +Cc1cc(C)cc(NC(=O)C(C)n2ccc3c(C)nn(C)c3c2=O)c1 +CCCC1CN(C(=O)Nc2ccc(C)c(NC(C)=O)c2)CCO1 +Cc1cc(C)cc(-n2nc(C(=O)OCC3CCC(=O)N3)cc2C)c1 +CC(Nc1cccc(Cl)c1)c1cccc(-n2cnnn2)c1 +Cc1ccc(C(=O)NCC(=O)N2CCOCC2)cc1 +COc1cccc(OCC(=O)NCc2ccccc2-n2ccnc2)c1 +Cc1c(C(=O)Nc2cccc(F)c2)cnn1-c1ccccc1 +CC(C)(C)n1cc(NC(=O)CSc2ccccc2F)cn1 +CC(C)OC(=O)CCNC(=O)N1CCCC(O)C1 +CCNC(=O)C(C)NC(=O)c1ccc(C(N)=O)cc1 +O=C(COCC1CCCO1)N1CCc2cc(F)ccc2C1 +O=C(NC1CC1)N1CCc2ncnc(-c3ccncc3)c2CC1 +C=CCN(CC=C)C(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 +COC(=O)C1(N(C)C(=O)c2csc(-c3ccco3)n2)CCCCC1 +Cc1cc(C)n(-c2cncc(NCCC(=O)NC(C)C)n2)n1 +O=C(Cc1ccccc1)Nc1ccccc1OC(F)F +CC(C)Oc1ccc2c(=O)n(CCCC#N)ccc2c1 +CCOc1cc(F)ccc1NC(=O)c1csc(C)n1 +CC(C)CCOC(=O)C1CC(=O)Nc2cc(F)ccc21 +O=S(=O)(c1cccnc1)N1CCOC(c2ccccc2)C1 +Cc1cc(C)cc(OCCN(C)C(=O)c2cccc3cn[nH]c23)c1 +Cn1nc(C(=O)Nc2ccc(Cl)c(Br)c2)ccc1=O +Cc1ccc2c(COC(=O)c3ccoc3C)cc(=O)oc2c1 +Cc1cc(Cl)c(Cl)cc1S(=O)(=O)Nc1ccccn1 +CNC(=O)C1CCCCN1C(=O)c1cccc(F)c1 +CC(C)CC(=O)N1CCCC1C(=O)N1CCNCC1 +COc1ncccc1CN(C)C(=O)CCc1nc2ccccc2[nH]1 +CCOc1ccccc1C(=O)NCC#CCOc1cccnc1 +CC(NC(=O)C(C)(C)C)C(=O)NC1(C#N)CCCC1 +CC(C)N(C(=O)c1cnc(C2CCCO2)s1)c1ccc(F)cc1 +O=C(Cc1c[nH]c2ncccc12)NCC1(c2ccc(F)cc2F)CC1 +Cc1ccccc1C1CCc2nc(C(=O)NCc3ccccc3)cn2C1 +Cc1ccsc1CNS(=O)(=O)c1cccs1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)NC1CCc2ccccc21 +O=C(NCC1Cn2cc(-c3ccccc3)nc2CO1)Nc1ccccc1 +O=C1CN(S(=O)(=O)c2c(Cl)cc(Cl)cc2Cl)CCN1 +CC(C)COCC(C)NC(=O)Nc1ccc2c(c1)COC2 +COc1cc(OC)cc(-c2nccn2Cc2ccccc2C#N)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)C1(C)CCCO1 +O=C(Cc1nc(-c2ccccc2)n[nH]1)Nc1cccc(Cl)c1 +CN(Cc1ccccc1F)S(=O)(=O)c1ccc(C(N)=O)cc1 +COc1cccc(C(O)CNc2ccc(NC(C)=O)cc2)c1 +Cc1cccc(-n2nnnc2SCc2n[nH]c(=O)[nH]2)c1C +Fc1cccc2c1CCNC2c1ccc2c(c1)OCCO2 +CS(=O)(=O)N1CCN(C(=O)C2(c3ccccc3)CCC2)CC1 +CC(C)c1nc2cccnc2n1Cc1ccccc1F +O=C(NC1CCCCC1n1cccn1)c1ccnc(OC2CCC2)c1 +O=S(=O)(c1ccc(F)cc1)N1CCN(CC(F)(F)F)CC1 +CCn1c(SCC(=O)c2ccc3c(c2)OCCO3)nnc1C(C)C +COC(CNC(=O)COc1ccc(C)cc1)c1cccc(F)c1 +Cc1noc(C)c1S(=O)(=O)Oc1ccc(NC(=O)C(C)C)cc1 +O=C(CCSc1ccccc1Cl)NCc1ccccn1 +Cc1ccc(C(O)CCC(=O)N(C)CCc2ccncc2)cc1 +Cc1ccc(CC(=O)Nc2sc3c(c2C(N)=O)CCC3)c(C)c1 +CC(NC(=O)C1(c2ccccc2)CCOCC1)c1ccncc1 +CCOC(=O)C1CCCN(c2cccc(N(C)C)c2)C1 +Cn1cnnc1C1CCN(C(=O)C2CCc3ccccc32)CC1 +Nc1ncnc2c1c1c(c(=O)n2-c2ccccc2)CCCC1 +COc1csc(C(=O)NCc2ccnc(OC(C)(C)C)c2)c1 +CC(=O)N1CCCSc2ccc(S(=O)(=O)NC(C)C)cc21 +CCN(CC)C(=O)Nc1ccccc1OCCOC +COc1ccc(C2NCCc3ccc(F)cc32)cc1OC +NC(=O)C1(NC(=O)c2c[nH]c3ccc(F)cc3c2=O)CCCC1 +CS(=O)(=O)N1CCCC(NC(=O)Nc2ccc3c(c2)CCC3)C1 +CNC(=O)c1nsc(C(=O)NCc2ccc(OC)cc2)c1N +CC(=O)Nc1ccc(S(=O)(=O)NCCn2nc(C)cc2C)cc1 +CCC(=O)N1CCc2cc(C(=O)Nc3cc(F)ccc3Cl)ccc21 +CCOc1ccc(N)cc1COc1ccccc1C +CC(=O)Nc1ccc(CN2CCOC(c3ccccc3F)C2)cc1 +CC(C)Cn1nccc1NC(=O)Cn1ccc2ccccc21 +CCC(NS(=O)(=O)c1ccc(O)cc1)C(C)C +COCCn1c(CCNC(=O)c2ccccn2)nc2ccccc21 +Cc1ccc(N2CC(c3nnc(NC(=O)N(C)C)s3)CC2=O)cc1 +Cn1nnnc1SCCC12CC3CC(CC(C3)C1)C2 +CC1C(=O)C(=O)OC1c1c(Cl)cccc1Cl +Cc1ccccc1NC(=O)COC(=O)CCc1ccncc1 +CCCNC(=O)Cc1nnc(-c2ccc(C)cc2)o1 +O=C(c1cnn2c1CCCC2)N1CCC(C(=O)N2CCCCC2)CC1 +Cc1ccc(C=c2sc3nc(-c4ccco4)nn3c2=O)o1 +CC(=O)n1ncc2cc(Br)c(F)cc21 +COC(=O)c1cc(OC)ccc1OCc1nc(C(C)C)no1 +O=C1C2CN(S(=O)(=O)C3CC3)CC2CN1c1cccnc1 +CCOc1ccc2c(C(=O)NCc3ccncc3)cc(=O)oc2c1 +NC(=O)c1cccc(S(=O)(=O)Nc2ccc3oc(=O)ccc3c2)c1 +CC(C)(C)n1nc(C(=O)NCCCC(N)=O)cc1C1CC1 +O=C(Nc1cccc(F)c1)C1CCCN1C(=O)c1cccc(F)c1 +COc1ccc(NC(=O)N2CCC3(CC2)CNC(=O)C3)cc1Cl +COc1ccnc(NC(=O)c2c(O)cc(Cl)cc2Cl)c1 +Cc1cccc2c1CCNC2C1COc2ccccc2O1 +Cc1ccccc1CNC(=O)c1scnc1C1CC1 +Cc1ccc(CN(C)C(=O)NCc2ccccc2)o1 +Cc1csc2nc3n(c(=O)c12)CCN(C(=O)C1CC1)CC3 +CCC1Oc2cccc(N)c2N(Cc2cccc(F)c2)C1=O +c1ccc2c(c1)CNC(CN1CCc3ccccc31)C2 +CCOc1ncnc2c1CCN(C(=O)C1CCCO1)CC2 +COC(=O)c1ccc(C(=O)N2CCc3ccccc3C2)cc1 +CCCC1CN(C(=O)Nc2cccn(CC(F)(F)F)c2=O)CCO1 +CCOC(=O)c1c(NC(=O)c2onc(C)c2Cl)sc(C)c1C +CC1(C)Cc2c(sc(NC(=O)Oc3ccccc3)c2C(N)=O)CO1 +CCCNC(C)(C#N)COc1cc(F)cc(F)c1 +CCCCS(=O)(=O)NCC(=O)NC1C=CCCC1 +COC(=O)CCC(=O)Nc1ccc(Oc2ccncc2)cc1 +CC1CN(C(=O)COC(=O)c2ccc(C#N)cc2)CC(C)O1 +CCN(Cc1cccc(F)c1)C(=O)CCc1c(C)n[nH]c1C +CCN(CCO)S(=O)(=O)CCc1ccccn1 +Cc1c(C(=O)NCC(=O)NCC(F)(F)F)sc2cccc(F)c12 +OC1COc2cc(OCC3CCCCO3)ccc21 +COc1cc2c(cc1OC)CCN(c1nc(C)cc(C)n1)CC2 +C=CCN(CCc1ccccc1)S(=O)(=O)c1ccc(C#N)cc1 +COCC(NC(=O)c1[nH]c(C)c(C(C)=O)c1C(C)C)C(N)=O +CC(C)(C)OC(=O)Nc1ccc2c(c1)ncn2C(=O)OC(C)(C)C +CCCc1nnc(NCCc2cccc(OC)c2)o1 +CC1Sc2ccc(C3CCCC(=O)C3)cc2NC1=O +COc1ccccc1NCC(=O)Nc1ccc(C(C)=O)cc1 +COCC(C)NC(=O)CCN1C(=O)CCc2ccccc21 +CCCc1nnc(NCC2(N3CCOCC3)CCCCC2)o1 +COCCN(CCC#N)Cc1cc(Br)ccc1F +CC(=O)N(C)CC(=O)NCc1cccc(OC(C)C)c1 +CCc1nnc(NC(=O)c2ccc(COC(C)C)o2)s1 +Cc1nc(N2CC(C)CC(C)C2)sc1C(C)O +CC(C)(C)Oc1cc(CNC(=O)Cc2ccccc2O)ccn1 +CCC(=O)NCC(=O)NCCn1c(C)nc2ccccc21 +CC(C)Nc1ncccc1C(=O)N1CCN(C(=O)CO)CC1 +Cc1ccc(S(=O)(=O)N2CCCC2C(=O)Nc2cccnc2)cc1 +CCOC(=O)c1cnn2ccc(NC(=O)NC(C)(C)C)cc12 +Clc1ccccc1-n1nc(Cn2cncn2)nc1C1CCC1 +CCSc1ccc(NC(=O)Nc2ncccc2C)cn1 +O=C(Cc1cccc(F)c1)NCCNC(=O)C1CC1 +CC(OC(=O)c1sccc1-n1cnnn1)c1cccc(C#N)c1 +COc1ccccc1C#CCNC(=O)CCn1ccc(=O)[nH]c1=O +O=C(c1ccc(-c2cc[nH]c(=O)c2)cc1)N1CCCCC1 +CCOc1ccc(S(=O)(=O)N2CCCC(C)C2)cc1OCC +Cc1cc(CN(C)Cc2noc(-c3cccs3)n2)no1 +Cc1nnc(C(C)NCC2(c3c(F)cccc3F)CCCC2)o1 +CC(=O)c1ccccc1NC(=O)COc1ccc(C#N)cc1Cl +COc1ccc(Br)cc1CNCc1nnc2n1CCC2 +Cc1nnc(NC(=O)c2cn(-c3ccccc3)nc2-c2ccccc2)o1 +CCn1c(SCCN2CCOCC2)nc2ccccc2c1=O +O=C1COc2ccc(COC(=O)CNC3CC3)cc2N1 +COc1cc(OC)cc(C(=O)N2CC(C)c3ccccc32)c1 +O=C(COc1cccc(-n2cnnn2)c1)NCCc1ccc(F)cc1 +CNC(=O)CCc1ccc(NC(=O)COc2cccc(C)c2)cc1 +Cc1ccc(C(C)NCC(O)c2ccc(F)cc2)o1 +COCCN1CC(C(=O)Nc2ccccc2)CC1=O +CCc1ccc(C(=O)NCCc2nnc(SC)n2C(C)C)cc1 +Cc1ccn(CCc2ccc3c(c2)CCO3)c(=O)c1 +NC(=O)Nc1ccc(CNS(=O)(=O)c2ccccc2Cl)cc1 +CCOc1ccc2c(C(=O)N(C)C3CCCCC3)cc(=O)oc2c1 +CC(NC(=O)c1ccc2nccn2c1)C1(N2CCOCC2)CCCC1 +CC(C)n1cnnc1CCNC(=O)Nc1nnc(C2CC2)s1 +Cn1nc(C(=O)NCC2CCC2)cc1NC(=O)C1CC1 +O=C(COc1cccc(F)c1)NC1CCCCC1 +CNC(=O)c1ccc(=O)n(Cc2cc(=O)oc3cc(C)ccc23)c1 +CC(=O)Nc1ccc(O)c(C(=O)c2ccc(Cl)cc2)c1 +O=C(Nc1ccccn1)c1c(-n2cnnn2)sc2c1CCC2 +COc1ccc(S(=O)(=O)N(C)C)cc1C(=O)NCc1cccnc1 +CCOC(=O)CCC(C)NC(=O)c1nc2nccc(C)n2n1 +CS(=O)(=O)NCC(=O)Nc1ccccc1N1CCCCCC1 +CN1C(=O)Cc2cc(NC(=O)c3cccnc3)ccc21 +CCNc1nc(SCC(=O)OC)nc(N2CCOCC2)n1 +CCS(=O)(=O)N1CCc2nc(NC(=O)C3CCCC3)sc2C1 +COc1ccc(NS(=O)(=O)c2cn[nH]c2)cc1OC +Cc1nc(N)n(CC(=O)NCc2ccco2)c(=O)c1C +Cn1c(C2CC2)nc2cc(NC(=O)CCC3CCCO3)ccc21 +CN(CCc1ccccc1)C(=O)CN1C(=O)OCC1c1ccccc1 +CCc1ccc(S(=O)(=O)N2CCC3(CCCN(C)C3=O)C2)cc1 +COCc1cccc(C(=O)N2CCN(C(C#N)c3ccccc3)CC2)c1 +CCC(C)C(=O)NC1CCN(S(C)(=O)=O)CC1 +Cc1ccc2c(c1C)OCC2NC(=O)N(C)Cc1cccnc1 +Clc1ccc(Nc2nccc(-c3ccncc3)n2)cc1 +O=C(CCCn1c(=O)c2cccn2c2cccnc21)N1CCCC1 +COCCNC(=O)CN(c1ccc(C)c(Cl)c1)S(C)(=O)=O +CC(C)NC(=O)c1ccc(CNC(=O)c2cnn3c2OCCC3)cc1 +Cc1cc(NC(=O)CSc2ncc(C#N)c(N)n2)ccc1Cl +CN(C(=O)c1cc2cccn2cn1)c1ccccc1 +Cc1cc(NC(=O)C(C)Cc2c(C)nn(C)c2C)c2ncccc2c1 +COC(=O)c1cc(OC)ccc1NC(=O)C(C)NC(=O)c1ccoc1 +O=C(Cc1c[nH]c2ncccc12)N1CCC2(CC1)OCCO2 +Cc1nn(C)c(C)c1CC(=O)Oc1ccc(C#N)cc1Cl +Cc1noc(C)c1CN(C(=O)Cc1ccccc1)c1ccccc1 +Cc1cc(C)n2nc(SCc3nnnn3C3CC3)nc2n1 +Cc1nc(C(N)c2cc(F)c(F)c(F)c2)sc1C +Cc1ncsc1C(=O)Nc1nc2ccc(Cl)cc2s1 +O=C(NCc1nnc2ccccn12)c1cnns1 +COc1ccc(CNC(=O)NCCN2CCOCC2)cn1 +Cc1noc(C)c1CCc1nc(-c2ccncc2)no1 +CCc1ccc(CNC(=O)CNc2cc(NC(C)=O)ccc2F)s1 +CCC(NC(=O)NCc1csc(C)n1)c1ccccc1OC +O=C(Nc1cccc(Cl)c1)c1scnc1C1CC1 +O=C(c1ccc(=O)[nH]c1)N1CCc2[nH]nc(Cc3ccccc3)c2C1 +O=C(NCCO)c1ccccc1C(=O)c1ccccc1 +COC(C)C(=O)NC1CCOc2c(Cl)cccc21 +Cn1cc(CN(C(=O)Nc2ccc(C(F)(F)F)cc2)C2CC2)cn1 +Cc1ccc(-n2nc(C(C)(C)O)c(=O)cc2C)cc1 +CCSc1[nH]c2ccccc2c(=O)c1C(=O)OC +COc1cc(C2CC(=O)Nc3[nH]ncc32)cc(OC)c1OC +CS(=O)(=O)NCCS(=O)(=O)c1ccccc1F +O=C(NCCNC(=O)C1Cc2ccccc2O1)c1ccco1 +CS(=O)(=O)NCCNC(=O)NCCc1cccc(F)c1 +CC(OC(=O)c1cc2ccccc2oc1=O)C(=O)c1ccccc1 +COc1cccc(C(=O)Nc2nn(C(C)C)cc2C#N)c1F +Cc1ccc(C2COCCN2C(=O)NC(C)COCC(C)C)o1 +N#Cc1noc(C(=O)NCCc2c[nH]c3ccccc23)c1N +CC(NC(=O)Cc1ccc2c(c1)OCC2)c1nnc2ccccn12 +C=CCNC(=O)Nc1cccc(C#Cc2ccccc2)c1 +O=C(Nc1cccc(Br)c1)c1cscn1 +COCCCOC(=O)c1ccc(F)c(NC(C)=O)c1 +CCc1nnc2sc(-c3ccc(OC)c(NC(=O)C(C)C)c3)nn12 +CNC(=O)c1c[nH]nc1-c1ccc(F)c(Cl)c1 +Nc1c(NCc2ccco2)ncnc1Nc1ccccc1F +Cc1ccn2cc(-c3ccc(NC(=O)CC(C)C)cc3)nc2n1 +c1cc2c(cc1-c1cn3c4c(sc3n1)CNCC4)OCCO2 +N#CC1CN(C(=O)NCC2CN3CCCCC3CO2)CCO1 +N#Cc1ccc(COC(=O)Cn2nc(-c3ccccc3)oc2=O)cc1 +CCn1c(SCCOc2ccccc2C)nnc1N1CCOCC1 +COCC(O)CN1CCN(c2nsc3ccccc23)CC1 +Cc1nc(C)c(CNC(=O)c2cn(C)nc2C(C)(C)C)s1 +CC(C)(C)CC(=O)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +O=C(Cc1ccccc1)Nc1cnc2ccccn2c1=O +Cc1ccc(NCc2ccc(C(N)=O)cc2)cc1F +Nc1oc(-c2cccs2)nc1-c1nc(-c2ccccc2)no1 +CC(=O)NCc1ccc(-c2nc(-c3cccc(O)c3)sc2C)s1 +Cc1cc(-n2cc(C(=O)NCc3ccccc3F)nn2)ccc1F +COc1ccc(OC(=O)COc2cccc(OC)c2)cc1 +O=C(Cn1ccnc1)Nc1cc(C2CC2)nn1-c1ccccc1 +CC(=O)Nc1ccc(C(=O)COC(=O)C2CC2C)c(F)c1 +CC(C(=O)NCc1n[nH]c(=O)c2ccccc12)n1cnc2ccccc21 +CCOC(=O)N1CCC(Nc2ccc3c(c2)COC3)CC1 +COc1ccc(S(=O)(=O)Oc2cccc3c2CCC3=O)cc1C +COc1ccc(O)c(C(=O)NCc2nnc3ccccn23)c1 +Cc1cc(C)c2sc(NCc3cccnc3)nc2c1 +CC(C)C(C)NS(=O)(=O)c1ccc(N2CCOC2=O)cc1 +COc1ccc(NC(=O)c2cc3ccccc3oc2=O)cn1 +Cc1nn(-c2ccccc2)nc1C(=O)Nc1ccc(C#N)cc1 +O=C(NCCO)Nc1cccc(COCC2CC2)c1 +COc1ccccc1-c1nn(C)cc1C(=O)NCCN1CCOCC1 +N#Cc1ccc(NCc2ccnc(OCC3CC3)c2)nc1 +COC(=O)CCC(=O)Nc1ccc(-n2cncn2)c(F)c1 +Cc1c(Cl)cccc1NC(=O)CS(=O)(=O)c1nncn1C +COc1ccc(C(C)NC(=O)c2cc(C3CC3)on2)c(OC)c1 +N#Cc1ccc(-c2cc(-c3ccncc3)nc3ncnn23)cc1 +Cc1ccc(C(C#N)N(C)C(=O)c2cccs2)cc1 +O=C(c1cc(=O)c(OCc2ccccc2F)co1)N1CCCC1 +O=C(c1ccc(S(=O)(=O)NC2CC2)cc1)N1CC(n2ccnc2)C1 +O=C(NCCOc1ccccc1F)c1ccc(-c2ccco2)[nH]c1=O +CC(C)C(=O)NCC(=O)N1CCC2(CC1)Nc1ccccc1NC2=O +CC(=O)Nc1ccc(C)c(NC(C)C(=O)Nc2ccccc2C#N)c1 +Cc1cc(C)c(OCC(=O)Nc2ccc(S(N)(=O)=O)cc2)c(C)c1 +Cc1nn2c(=O)cc(CN3CCc4ccc(O)cc4CC3)nc2s1 +COCCn1nc(C)c(CNc2ccc3nccnc3n2)c1C +COc1c(C)cnc(CNC(=O)NCC(C)c2nc(C)cs2)c1C +COc1cccc2c1C(CC(=O)N1CCCCC1)CC2=O +COCSc1nnc(-c2cccnc2)n1Cc1ccccc1 +CN(CCC#N)C(=O)COc1ccc2ccccc2c1 +Cc1nn(C)c(C)c1CCC(=O)N(Cc1ccccc1)c1ccccn1 +CCOC(=O)C(C)(C)N(C)C(=O)c1ncn(-c2ccccc2)n1 +CN(C(=O)Nc1ccncc1)C1CCN(c2ccccc2)C1=O +O=C(Nc1ccc(C(=O)OC2CCCCC2=O)s1)c1ccco1 +CC1(C)CCC(CNC(=O)CCC2CCOCC2)CC1 +CCNC(=O)CNC(=O)c1cc2sccc2n1C(C)C +COc1cc(-c2noc(-c3cc4ccccc4o3)n2)ccn1 +Cc1cccc(NS(=O)(=O)c2cc(C(=O)NCCO)ccc2C)c1 +O=C(Nc1cccc(-n2cccn2)c1)C1CCCN1C(=O)C1CC1 +CCc1cc(Cl)ccc1NC(=O)NC(C)c1n[nH]c(=O)[nH]1 +CC(C)CN(C(=O)Cn1c(-c2cccnc2)noc1=O)C1CC1 +Cc1ccc(NC(=O)CCn2cc(C)cn2)c(F)c1 +COC1CCC(CC(=O)NC2(C)Cc3ccccc3C2)CC1 +Cc1ccccc1N(C)C(=O)c1cccc2c1SCCC2=O +Cc1ccc(CC(=O)NCC(=O)N2CCCc3ccccc32)cc1 +O=C(NC1CC1)N1CCN(CC(F)(F)C(F)F)CC1 +COc1ccccc1C1=NCC(=O)Nc2sc3c(c21)CCC3 +N#Cc1cc(F)c(S(=O)(=O)N2CCOCC2C2CC2)c(F)c1 +NC(=O)c1ccccc1NC(=O)Cc1cccc(N)c1 +COc1ccc(C)cc1-c1c(N)nc(C)nc1C(F)(F)F +CSc1ccc(CN(C)C(=O)c2cnn(C)c2)cc1 +NS(=O)(=O)CCNC(=O)c1cc2c(s1)-c1ccccc1CC2 +O=C(NCCOc1cccc(Br)c1)Nc1cccnc1 +O=C(Cn1ccc(=O)[nH]c1=O)NCC1(c2ccc(F)cc2)CCC1 +Cc1ccc(F)cc1NC(=O)c1ccccc1S(C)(=O)=O +COc1ccc(-c2csc(C3CC3)n2)cc1Br +O=C(NCc1ccccn1)NCC1CCN(c2ccccc2)C1 +CNC(=O)c1cccc(CNC(=O)c2c(C)cc(C)cc2C)c1 +Cc1cccc(NCC(=O)Nc2c(C)cccc2C)c1 +O=C(C1CCCO1)N1CCCC2(COCCN(c3ncccn3)C2)C1 +CC(Cn1cncn1)NC(=O)NCC1CN2CCCCC2CO1 +Cc1ccc(S(=O)(=O)N2CCNC(=O)C2(C)C)cc1 +COc1cc(C(=O)N(C)C2CCCCC2)ccc1OC(C)C +O=C(Cn1c(=O)cnc2ccccc21)NC1CCCC1 +CCn1c(=O)sc2cc(Br)ccc21 +CCC(C)(C)c1ccc(CNC(=O)NCc2ncn(C)n2)cc1 +O=C(CCc1ncc(-c2ccccc2)o1)Nc1ccc[nH]c1=O +CCn1nc(-c2ccc(OC)c(Cl)c2)cc(N)c1=O +CCCCc1c(C)nc2nc(SCC3(CO)COC3)nn2c1C +CC(NC1CCc2ccccc21)C(=O)NC(C)(C)C +CCn1nc(C(=O)N(C)Cc2ccccc2F)c(=O)c2ccccc21 +CCCCC(=O)NC(C)c1cccc(S(N)(=O)=O)c1 +CC(Sc1ccccc1Cl)C(=O)N(C)CC(=O)NC1CC1 +O=c1onc(-c2ncccn2)n1CC=Cc1ccccc1 +O=C(Nc1ccc2c(c1)OCCO2)Nc1c[nH]nc1-c1ccccn1 +O=c1[nH]c2ccccc2c(=O)n1Cc1ccccn1 +CS(=O)(=O)N1CCN(S(=O)(=O)c2cc(F)ccc2F)CC1 +CCCC1CN(C(=O)c2cccnc2Nc2ccccc2F)CCO1 +COc1ccc(CCNC(=O)CSc2nncc(=O)n2N)cc1 +CC(C#N)NS(=O)(=O)c1ccc2[nH]c(=O)oc2c1 +N#Cc1ccc(NCC(=O)c2cc(F)ccc2F)cc1 +CCCOc1ccc(-c2nc(N)nc(C)c2C(=O)OCC)cc1 +CCCCNC(=O)C(C)S(=O)(=O)c1ccc(C)cc1 +CCC(C)N(C)C(=O)CCc1nc(-c2cccs2)no1 +CCc1[nH]c(C(=O)NC(C)c2ccccn2)c(C)c1C(=O)OC +Cc1c(Cl)cccc1NC(=O)c1cccc(O)c1 +NC(=O)COc1cccc(Cn2ccc(-c3ccccc3)n2)c1 +COCc1cccc(C(=O)N2CCN(C(C)=O)CC2)c1 +Cn1c(N)nnc1SCCOc1cccc(Cl)c1 +Cn1cc(CNc2ccccc2)c(-c2cccnc2)n1 +O=C(NCCc1ccc2c(c1)OCO2)NCc1ccco1 +COc1ccccc1Nc1nccc(-c2nnc3ncnn3c2C)n1 +C#CCCN1CCN(C(=O)c2cc(C)ccc2O)CC1 +C#CCOCC1CCN(C(=O)CCS(=O)(=O)c2ccccc2)CC1 +COCc1ncc(C(=O)NCCC2=CCCCC2)c(N)n1 +Cc1ccc(Br)cc1COC(=O)CN +O=c1c2ccccc2cnn1Cc1nc(-c2ccccn2)no1 +O=C(NCC1CC1)Nc1ccc(-n2cncn2)c(F)c1 +O=C(c1ccc(CNc2ccc(F)c(Cl)c2)cc1)N1CCCC1 +COc1ccc(C(C)OC(=O)CCc2cnn(C)c2)cc1F +COC(=O)c1cc(Br)cc2c1cnn2C(C)=O +Cc1cc2cc(C#N)c(SCC(=O)N3CCOCC3)nc2cc1C +Cc1cc(C(=O)N2CCN(c3ccccc3C#N)CC2)on1 +N#Cc1ccc(Cl)c(NC(=O)c2cccc(F)c2)c1 +CSc1ccc(CNC(=O)c2ncoc2-c2cccs2)cc1 +O=C(NCC1(N2CCOCC2)CCCCC1)c1ccc(F)cc1 +CC(C)(C)OC(=O)NCC(=O)n1nnc2ccccc21 +Cc1[nH]ncc1S(=O)(=O)Nc1ccccc1C(C)C +COC(=O)c1cccn2nc(-c3ccc(O)c(OC)c3)nc12 +Cc1ccc(S(N)(=O)=O)cc1C(=O)Nc1cnn(C)c1 +CN(CCC(F)(F)F)C(=O)Cc1ccc(-n2cnnn2)cc1 +NC(=O)c1ccc(NCc2nc(Cc3ccccc3)no2)cc1 +Cc1ccc(CNC(=O)C2CCCN(c3cn[nH]c(=O)c3)C2)cc1 +O=C(CNC(=O)c1cccc(F)c1)NCc1ccco1 +CN(Cc1cccc(C#N)c1)C(=O)CNC(=O)NCc1ccco1 +CNC(=O)c1c(C)cccc1NC(=O)CN(C)C(=O)OC(C)(C)C +CCc1ccc(COC(=O)CNC(=O)c2ccccc2)cc1 +CCN(Cc1ccccc1)C(=O)COc1ccccc1OC +CC(=O)c1cccc(-n2cnnc2Cn2nc(C)c(C)c2C)c1 +Cc1ccc(C(=O)CCC(=O)Nc2ccccc2C#N)cc1C +c1ccc(CCc2noc(Cn3ccnc3-c3cccnc3)n2)cc1 +Cc1cnc(NC(=O)CNC(=O)C(C)(C)C)s1 +CCOC(=O)CN1CCN(CC(=O)NC2CCCC(C)C2)CC1 +CCc1onc(C)c1NC(=O)N1CCN(c2cccc(O)c2)CC1 +COCCOc1cccc(CN2CCc3nc(C)[nH]c(=O)c3CC2)c1 +COc1cccc(NC(=O)Nc2ccc3c(c2)N(C)C(=O)CS3)c1 +C=CCc1cc(C(=O)Nc2cccc3cnccc23)cc(OC)c1OC +CC(C)CN1CC(C(=O)Nc2ccc3c(c2)COC3=O)CC1=O +CC(C)(C)OC(=O)N1CCC(COc2ncc(Cl)cn2)CC1 +COCCNC(=O)c1cc(C(=O)c2ccc(C(C)(C)C)cc2)c[nH]1 +CNC(=O)c1cc(NC(=O)c2cn(C)nc2C(C)(C)C)ccc1Cl +CN1CCN(C(=O)c2ccc(-n3cncn3)nc2)C(c2ccccc2)C1 +Cc1cc(NC(=O)c2ccnc(OCC(F)F)c2)sn1 +Cc1ccc(C(=O)NC2CCc3ccccc32)cc1 +CCN(C(=O)CCSc1ccccn1)c1cc(C)ccc1C +Cc1ccc(NC(=O)C(C)Sc2ncn[nH]2)cc1Cl +Cc1ccccc1-n1ncc2c(N3CCC(C(N)=O)CC3)ncnc21 +Cc1cc(NC(=O)CNC(=O)OCc2ccccc2)no1 +CCCCc1cc(NC(=O)c2nnn(-c3ccc(C)cc3)c2C)[nH]n1 +CN(C)S(=O)(=O)NCc1cccc(C(=O)NC2CC2)c1 +CCOC(=O)c1c(C)csc1NC(=O)CC#N +COc1ccc(Br)cc1S(=O)(=O)NC(C)(C)C +COC(=O)C1CCN(c2nc3ccccc3nc2C)CC1 +Cc1ccc(C(=O)CSc2nnc(C)n2CC(N)=O)cc1C +CCCNC(=O)c1cccc(C(=O)N2CCC(NC(C)=O)CC2)c1 +CC(=O)c1cccc(OCC(=O)Nc2ccc(C(N)=O)cc2)c1 +O=C(CSc1nncs1)c1c[nH]c2ccccc12 +CC(C)C(=O)Nc1cc(C(=O)Nc2ccccc2)nn1-c1ccccc1 +NC(=O)c1ccc(OCC(=O)Nc2ccccc2Cl)cc1 +Cc1oc(S(N)(=O)=O)cc1C(=O)N1CCc2ccccc21 +Cc1cc(C)c2nc(NCCCN3CCOCC3)sc2c1 +O=C(Cc1ccc(O)cc1)NCCc1ccccc1F +O=C(CCCn1cccc1)NCCc1ccc(Cl)cc1 +N#Cc1ccc(CNc2cnn(-c3ccccc3Cl)c2)cc1 +CCOc1ccc(CNC(=O)Cc2nnc(-c3ccsc3)o2)cc1 +CSc1nc2nc(C)c(CC(=O)Nc3ccc(C)cc3)c(C)n2n1 +O=C(NC1CCN(c2cccc(OC(F)(F)F)c2)C1)c1cc[nH]n1 +Cc1ccc(C(=O)NC2CC3C(=O)NC(CO)C(=O)N3C2)cc1 +CCCc1nc(CN(CC)C(=O)CC2CCCCC2)no1 +CN(Cc1cccc(F)c1)C(=O)c1ccc(-c2ccccc2)[nH]c1=O +Cn1nnnc1SCC(=O)Nc1sc2c(c1C#N)CCC2 +COCCCN1C(=O)CCC2CN(c3cccc(C#N)n3)CCC21 +CCN(CCO)c1ncnc(Nc2ccc(C)cc2C)c1N +CN(C)C(=O)Cn1cc(C(=O)Nc2cccc(OC(F)F)c2)nn1 +Cc1cnc(NC(=O)N(C)C2CCCCC2)s1 +CC(=O)NC(C(=O)N(Cc1ccccc1)CC1CCC1)C1CCCC1 +Cc1ccoc1C(=O)N1CCN(C(=O)c2occc2C)CC1 +O=C(NCCc1coc(-c2ccccc2)n1)c1ccc2c(c1)OCO2 +Cc1ccc(CNC(=O)COc2cccc(-n3cnnn3)c2)cc1 +COc1ccc(NC(=O)COc2cccc3c2CCC3=O)cc1 +COc1cccc(NC(=O)NC(CCO)C2CC2)c1 +CCOc1ccc(-c2nc(C#N)c(N3CC(C)OC(C)C3)o2)cc1 +CCOC(=O)c1cn(Cc2ccc(Cl)c(Cl)c2)cn1 +O=C(c1cccc(C2OCCCO2)c1)c1ccco1 +FC(F)(F)Cn1ccnc1Cn1cc(-c2ccccc2)cn1 +CC(Oc1ccc(Cl)cc1Cl)C(=O)N1CCN(C)CC1 +CN(Cc1cnn(C)c1)C(=O)NC1CCC2(CC1)OCCO2 +CCOC(C)c1noc(CN2CCN(c3cccc(OC)c3)CC2)n1 +N#Cc1ccc(C(=O)NCCSc2ccccc2)cc1 +COCC(=O)N1CCN(Cc2csc(-c3cccs3)n2)CC1 +O=C(Nc1nc2c(cc3c4c(cccc42)CC3)s1)c1ccno1 +O=C(Nc1cccc2cccnc12)N1CCCC1c1ccc[nH]1 +COC(=O)c1sc(NC(=O)C(C)Oc2cccc(F)c2)nc1C +CNC(=O)c1cccc(NC(=O)CN2CCc3ccccc32)c1 +Cc1cccc(CS(=O)(=O)NCc2cnn3ccccc23)c1 +COc1ccccc1CNC(=O)CN1CCN(c2ncccn2)CC1 +O=C(NCc1ccc(CN2CCOCC2)cc1)Nc1ccccc1 +CN(C)c1nc(CNc2cccc(F)c2F)ns1 +CC(CNC(=O)NCc1ncn(C)n1)Oc1ccc(F)cc1 +Cc1ccccc1C(C)NC(=O)NC(C)c1c(C)noc1C +CC(C)N(CCO)S(=O)(=O)c1ccc2c(c1)N(C)CCC2 +CCOc1ccc(F)c(C(=O)NCC(C)C(=O)OC)c1F +Cc1nn(C)c(C)c1NC(=O)Cc1noc2ccccc12 +CS(=O)(=O)N1CCOC2C(OCC(=O)N3CCCC3)CCC21 +CCc1nnsc1C(=O)Nc1ccnn1C1CCCCC1 +COc1ccccc1NC(=O)CSc1nc2ccccc2o1 +COc1cccc(N2CC(C(=O)NCc3nc(C)cs3)CC2=O)c1 +O=C(Cn1cnnn1)NCC1Cc2ccccc2O1 +OCCCn1nnc(CO)c1COc1ccccc1Cl +N#Cc1ccccc1CNc1ccc(C(=O)NC2CC2)cc1 +O=C(CCC1CCCO1)Nc1cccc(Oc2ccncc2)c1 +CCOC(=O)c1cc(S(=O)(=O)NC2CCCCCC2)c(C)n1C +CCOC(=O)CCC(=O)c1cc(C)ccc1OC +O=C(COc1ccc2ccc(=O)oc2c1)NCCOc1ccccc1 +C=CCNC(=O)c1ccc(S(=O)(=O)C(C)C)cc1 +CC(Sc1ccccc1Cl)C(=O)NC1CCCc2occc21 +COc1ccc(NC(=O)CN(C)C(=O)CCn2cncn2)cc1 +CS(=O)(=O)N1CCN(CC(O)c2ccccc2)CC1 +Nc1cc(F)cc(Br)c1OCc1ccccn1 +Cc1ccc(Cl)cc1NC(=O)CSc1n[nH]c(=O)n1C +CC(C)OCC(=O)N1CCCN(c2ccc(F)cc2)CC1 +O=S(=O)(NCCN1CCOCC1)c1ccc(Br)cc1 +O=C(CCCOc1ccccc1)Nc1nc2c(s1)CCC2 +CC(C)OCC(=O)N1CCCC(C(=O)c2cccc(OC(C)C)c2)C1 +CC(=O)NCCC(=O)NCc1ccc(C)cc1OC1CCCCC1 +Cc1cc(CN(Cc2ccccn2)Cc2sccc2C)n(C)n1 +CC(=O)NC1CCCN(Cc2ccc(C#N)cc2Br)C1 +COCCN(CCC#N)S(=O)(=O)c1ccc(F)cc1Cl +CCOC(=O)N1CCN(C(=O)c2nc(-c3ccccc3)oc2C)CC1 +CC(C)CN(C)C(=O)c1cc2ccccc2c(=O)[nH]1 +CC1CCC(N(C)C(=O)CSc2ccc(C#N)cc2)CC1 +CN(CC1CCCO1)C(=O)NCCNC(=O)C(C)(C)C +CC(C)Oc1ccc(-c2nc3ccc(F)cn3c2N)cc1 +O=C(NCCc1ccccc1)NCC(=O)N1CCCCC1 +CNC(=O)c1nnsc1Sc1c(C(=O)NC)nnn1C +COC(=O)C(NCc1cc(F)ccc1Br)C(C)C +Cc1cc(CN(C)Cc2nccs2)ccc1F +Cc1csc(C(C#N)C(=O)c2cnn(C)c2-n2cccc2)n1 +CCOc1cc(F)ccc1NS(=O)(=O)c1ccc2c(c1)CCO2 +CC(Oc1cccc(Cl)c1)C(=O)Nc1ccc(C(N)=O)cc1 +CCOC(=O)c1c(C)nc(N)nc1COc1ccccc1C +COCCNC(c1nccs1)c1c(F)cccc1F +CCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(C)s1 +Nc1nccc(CC(O)(c2ccccc2)c2ccccc2)n1 +CN1C(=O)CCc2cc(C(=O)NCc3csc(=O)[nH]3)ccc21 +CCS(=O)(=O)NCCSc1nc2ccccc2s1 +CCOCC(=O)Nc1ccc(OC)c(-n2cnnn2)c1 +O=C1COc2ccc(C(=O)N3CCC(O)C3)cc2N1 +Cc1nc(C2CCCN2C(=O)COCC2CC2)no1 +Cc1cc2oc(C(=O)Nc3ccn(CC#N)n3)c(C)c2cc1Cl +CC1CCc2c(C(=O)Nn3cc(Br)cn3)csc2C1 +CN1C(=O)Cc2cc(S(=O)(=O)NC(C)(C)C#N)ccc21 +CN1CC2CCC(CC1=O)N2C(=O)Cn1sc2ccccc2c1=O +CCn1nc(C2CC2)nc1-c1ccc(O)c(Cl)c1 +O=C(CNC(=O)c1csc2ncccc2c1=O)NC1CCCCC1 +O=S(=O)(Cc1csc(-c2ccccc2F)n1)c1nccs1 +CN(C)c1nc(=O)c2cccnc2n1Cc1ccc(F)cc1 +OCCC1CN(Cc2ccc(F)cc2)CCN1Cc1cccs1 +CCC(=O)N1CCc2c(c(C(=O)NCc3ccc(F)cc3)nn2C)C1 +COc1ccccc1CC(=O)NCCCn1ccc2ccccc21 +O=C(Cn1ccccc1=O)NCc1ccc(OCC(F)(F)F)nc1 +Nc1cc(Br)c(Br)cn1 +CN(Cc1cccc(OC(F)F)c1)C(=O)Cc1n[nH]c2ccccc12 +Cc1cc(C)c(CNC(=O)c2ccc(-n3cccc3)c(F)c2)c(=O)[nH]1 +O=C(C1CNCc2cccc(Cl)c21)N1CCOCC1 +CC(C)N(CC(N)=O)C(=O)Cc1cccc2ccccc12 +CN(CCC(F)(F)F)C(=O)c1cccc(OCc2cccnc2)c1 +O=C(CCn1ccccc1=O)N1CCCC1c1ccccc1 +CC(C)=CC1C(C(=O)N2CCCC2C(=O)N(C)C)C1(C)C +NC(=O)C(NC(=O)c1ccc(F)cc1OC(F)F)c1ccccc1 +O=C(C1CCCCC1)N1CCN(CC(O)c2ccco2)CC1 +Cc1cc(OCC(=O)NC(C)C)c2c(C)cc(=O)oc2c1 +Cc1ccccc1CS(=O)(=O)N1CCOc2ccc(F)cc21 +CCCC(=O)Nc1c(C)cnn1Cc1cc(F)ccc1F +Cc1ccc(CNC(=O)COC(=O)c2ccccc2F)cc1C +O=C(c1ccccc1Br)N1CCCC1CO +Cc1cc(C(=O)N(C)C2CCN(c3ccccc3Cl)C2=O)c(C)o1 +CC(C)(CNC(=O)C1CC(=O)Nc2cc(F)ccc21)c1ccncc1 +CN(C)S(=O)(=O)c1ccc(N2CCOC2=O)cc1 +C=C(C)COc1ccc(C(O)CCN2CCOCC2)cc1 +COC(C)C(=O)NCc1ccc(S(C)(=O)=O)cc1 +Cc1ccc(-c2nc3n(C)c4ccccc4n3c2CCC(N)=O)cc1 +CN(Cc1ccccn1)C(=O)c1ccc(OCC(F)F)nc1 +COCC(NC(=O)c1cc(OC)ccc1Br)C(N)=O +CC(C)(C)c1nn(-c2ccccc2Cl)c(=O)o1 +CC(C)(C(N)=O)c1ccc(NC(=O)c2cccc(OC(F)F)c2)cc1 +CCOc1ccccc1NC(=O)Cn1cc(C(F)(F)F)ccc1=O +CCC(CC)N(CCO)c1ccc(C(F)(F)F)cn1 +CC(=O)N1CCC2(CC1)CC(NC(=O)C1CCC1)c1ccccc1O2 +CN(C)S(=O)(=O)c1cccc(-c2cn3cc(Cl)ccc3n2)c1 +CC1CCCCC1NC(=O)C1CC1(Cl)Cl +Cn1c(=O)c2c(SCC#N)nc(-c3ccccc3)nc2n(C)c1=O +CC(C)(C)c1nnc(SCC(=O)OCc2ccccc2)n(N)c1=O +O=C(CC1CCCO1)Nc1ccnc(Sc2ccccn2)c1 +C=CCN(Cc1cccs1)C(=O)c1cnc2ccc(C)cn12 +Cc1ccc(C(=O)N2CCCC3(CC(Oc4cccnc4)CO3)C2)o1 +Cn1c(SCc2ccccn2)nnc1-c1ccco1 +O=C(Nc1ccc(Cl)cn1)c1cncc(Br)c1 +COc1ccc2c(c1)C(=O)NC2CC(=O)NCCC(C)C +Cc1noc(C)c1CCC(=O)N1C(C)COC(c2ccccc2)C1C +CC(Cc1ccccc1F)NC(=O)NC(C)C1CCCO1 +Cc1cc(C)c(NC(=O)c2cnccn2)c(Cl)c1 +CCNC(=O)CN1CCN(Cc2nc(-c3ccco3)no2)CC1 +Cc1cc(O)c(C2(c3c(O)cc(C)[nH]c3=O)CCCC2)c(=O)[nH]1 +Cn1cc(Nc2cccc(NC(=O)Cc3noc4ccccc34)c2)cn1 +CCC(O)(CC)CNC(=O)C(C)Sc1ccccn1 +CCNC(=O)CN1CCN(CC(=O)OC(C)(C)C)CC1 +COCCOC(=O)c1ccc(-n2cnc3ccccc32)nc1 +OCCc1csc(-c2ccc(Br)cc2)n1 +CCC(=O)NCc1ccc2c(c1)CCN2C(=O)c1ccc(F)cc1 +Cc1cc(C)cc(CCNC(=O)N2CCC3(CC2)OCCO3)c1 +C=CCOc1ccc(NC(=O)C2CCCN(S(C)(=O)=O)C2)cc1 +COCCCNC(=O)c1c(C)noc1-c1cccc(F)c1 +O=C(OCc1ccc(F)cc1)c1cnc(C2CCCO2)s1 +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)N1CCC1 +Cc1nn(-c2ccc(C(C)O)cc2)c(C)c1Br +CCCN(C)S(=O)(=O)c1ccc(OC(C)C)c(C)c1 +c1cncc(Cn2ccnc2-c2cccc(-n3cccn3)c2)c1 +CC(C)n1nnnc1COc1cccc(C(=O)Nc2ccccn2)c1 +CC(=O)Oc1ccc(C(=O)Nc2nc3c(s2)CNC3)cc1 +Cc1ccc(SCCC(=O)Nc2ccnc(C)c2)cc1 +CC(NC(=O)c1csc(Nc2ccccn2)n1)c1ccccc1 +CCC(CC)n1ccc(C(=O)NC2(C(=O)OC)CCCC2)n1 +O=C(CCc1ccc2c(c1)OCO2)NCCc1nnc2ccccn12 +CCC(c1ccc(F)cc1F)N1CCn2c(nn(C)c2=O)C1 +Cc1ccc(Cl)cc1N1CCN(C(=O)Nc2ccccn2)CC1 +CCN(CC)C(=O)COc1cccc(NC(N)=O)c1 +O=C(OC1CCCC1)c1cccc(S(=O)(=O)NCC2CC2)c1 +O=C(Nc1ccccn1)C1C2CC3CC(C2)CC1C3 +CCN(CC)C(=O)COC(=O)c1ccc2c(c1)nc(C)c(=O)n2CC +Cc1cc(CSc2nccn2Cc2ccccn2)on1 +COC(=O)NCCCC(=O)NCc1cc(C)oc1C +Cc1nn(CC(=O)NCc2ncn(C)n2)c(C)c1Cl +COc1ccc(CCC(=O)NCCS(N)(=O)=O)cc1 +NC(=O)CC12CC3CC(CC(Br)(C3)C1)C2 +CC(C)C(=O)N(CCC(N)=O)c1ccc(F)cc1 +CC(C(=O)Nc1ccc(Oc2cccnc2)nc1)c1cccs1 +CN(C)C(=O)COc1ccc(NC(=O)N2CCCC2)cc1 +CCn1nc(Cn2cncn2)nc1CN1CCCCCC1=O +Cc1ccc(NC(=O)COCC2CCCO2)cc1F +O=C(NCc1ccc2c(c1)CCC2)c1ccc(-n2ccnn2)cc1 +Oc1cc(O)c2c(c1)C(c1ccc(F)c(F)c1F)NCC2 +Cc1nsc(N2CCN(Cc3cnc(C(C)C)s3)CC2)n1 +CCC(C)(C)C(=O)NCc1cccc(S(N)(=O)=O)c1 +O=C(Cn1ccccc1=O)N1CCN(c2cnccn2)CC1 +COc1ccc2c(c1)CCCN2C(=O)c1ccc(C)nc1 +CCOCC(=O)Nc1nc2c(C)cccc2s1 +COC(=O)C1=C(C)C(C(=O)NCCN(C)c2ccccc2)=NC1C +COc1cc2c(c(OC)c1)C(c1cccc(C)c1)CC(=O)N2 +Cc1noc(NC(=O)c2ccc(F)cc2Cl)n1 +COc1ccc2sc(C(=O)Nc3nncs3)c(Cl)c2c1 +Cc1ncsc1CNC(=O)c1cn(C)nc1C(C)(C)C +CC1CN(S(=O)(=O)c2ccc(N)cn2)CC(C)O1 +CCSc1cc(C(=O)Nc2nc3c(s2)CN(CC)CC3)ccn1 +O=C(NCCO)c1cccc(Oc2ccccn2)c1 +O=C(NC1CC1)C1CN(C(=O)c2cccs2)CC1c1ccccc1 +O=S(=O)(Cc1cccc(Cl)c1)NCCN1CCOCC1 +Cc1ccc(C(O)CN2CCN(c3ncccn3)CC2)cc1N +CNC(=O)c1cccc(CCNCc2cc(OC)c3c(c2)OCO3)c1 +CNC(=O)NCC(=O)Nc1ccc(NC(C)c2ccccc2)cc1 +Cc1[nH]c2ccccc2c1C1=CCN(C(=O)Nc2cccnc2)CC1 +CN1CC(NC(=O)c2cccc(-c3ccoc3)c2)CCC1=O +CC(C)N1CCOC(CC(=O)NCc2ccccn2)C1 +O=C(NCc1ccnc2ccccc12)c1ccnc(OC2CCC2)c1 +CC1Cc2ccccc2N1C(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +CCCc1ccccc1NC(=O)CNC(=O)c1ccsc1 +Cc1cccc(OC2COCCN(S(C)(=O)=O)C2)n1 +Cc1n[nH]c2ncc(C(=O)N(Cc3nccn3C(F)F)C3CC3)cc12 +Cc1nn2ncc(C(=O)N(C)C3CCCCC3)c2[nH]1 +O=C(NCC1CCN(C(=O)c2ccccc2F)CC1)c1ccccn1 +Cc1ccc(Nc2c3c(nc4nc(C)nn24)CCC3)cc1 +CC(C)N(C(=O)c1csc(-c2cnccn2)n1)C1CCCCC1 +CCn1cc(C(=O)Nc2ccccc2Sc2nccn2C)cn1 +COc1ccc(-n2nnc(C#N)c2-c2ccccc2Cl)cc1 +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)Oc1ccccc1 +CC(=O)Nc1cc(S(=O)(=O)Nc2ccccc2)ccc1C +COc1ccc(-c2cn[nH]c2-c2cc(OC)c3c(c2)OCO3)cc1 +CC(Cn1cccn1)OC(=O)c1ccccc1Cl +O=C(Nc1cccc(Cn2cccn2)c1)c1c(F)cccc1F +CC(C)N(CCC#N)C(=O)c1cccc(Cl)c1 +O=C(N1CC(n2ccnn2)C1)C1(c2cccc(F)c2)CCC1 +O=C(NCCc1ccccc1F)c1ccc(-n2cccn2)cc1 +Cc1cnn(CC(=O)NCCc2ccc(Cl)cc2)c1 +O=C(c1ccoc1)N1CCC(Oc2ccc(Cl)cc2)CC1 +Cc1cc(C)n(Cc2ccc(C(=O)N3CCCCC3)o2)n1 +COc1cccc(NCc2nn(Cc3ccccc3Cl)c(=O)[nH]2)c1 +COc1ccc(C(C)=O)c(OC(=O)c2ccn(C)c(=O)c2)c1 +Cc1cc(S(=O)(=O)Nc2ccc(=O)n(C)c2)ccc1OC(C)C +CC(=O)NCCNC(=O)CCc1ccccc1Cl +Cc1cccc(C(C)C)c1NC(=O)c1ccc2c(c1)OCC(=O)N2 +CC1CCCCC1OCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CC(C)NC(=O)c1ccc(NC(=O)c2cccc(Cl)c2)cc1 +Cc1cc2ccccc2n1CC(=O)NCC(C)(C)c1ccncc1 +N#Cc1ccc(OC(F)F)c(NC(=O)NCc2ccccc2CO)c1 +NC(=O)c1cc(NCc2nc(-c3ccccc3)no2)ccc1F +Cc1cc(O)c(C(C)C)cc1NC(=O)CCN1CCCC1=O +CCSc1ccc(C(=O)NC2COc3c(cccc3OC)C2)cn1 +COc1ccc(CNC(=O)c2cc(=O)c3ccccc3o2)cc1F +COCC(NC(=O)Nc1nc(CC(C)C)n[nH]1)c1ccnn1C +Cc1noc(C2CCCN(S(=O)(=O)c3c(F)cccc3F)C2)n1 +N#CC(NCc1ccncc1)c1cccc(Cl)c1Cl +COc1cccc(CNC(=O)c2cccc3ncccc23)c1 +CCn1ccc2c(OCC(=O)NC(C)C)cccc2c1=O +COC(=O)c1ccc(OCC(=O)Nc2ccc(OC)cc2)cc1 +CCOCCCNC(=O)c1ccc2snnc2c1 +O=C(NC1CC1)C1CN(Cc2ccccc2)CC1C(=O)c1ccccc1 +Cc1ccc2c(c1)oc(=O)n2C(=O)COc1ccccc1 +CN(C)C(=O)CCNC(=O)Nc1cc(F)ccc1F +N#CC1(c2ccccc2Br)CCC(=O)CC1 +COC(=O)NCC(=O)N1CCC(Nc2ccccc2)CC1 +CCC(C)NC(=O)c1ccc(CNC(=O)c2ccc(C)s2)cc1 +CCC(Nc1cccc(OC)c1)C(=O)N1CC(O)C1 +CCCS(=O)(=O)NCC(O)c1ccc2c(c1)CCCC2 +Cc1cc(C)n(CC(=O)Nc2ccccc2N2CCNC(=O)C2)n1 +Cc1ccc(CN(C)C(=O)c2ccc(NC(=O)c3ccco3)cc2)cc1 +CCOC(=O)CSc1nnc(-c2ccco2)n1C(C)C +Cc1nn(C)cc1NC(=O)NCC(c1ccncc1)N1CCOCC1 +CC(=O)N(C)c1ccc(NC(=O)Nc2ccc(F)cc2)cc1 +CCCN(CC1CC(C)CCC1=O)CC(F)(F)F +CCN1CCN(C(=O)c2c(C)c(N)c[nH]c2=O)CC1 +COC1CCCN(C(=O)CNC(=O)Nc2cccc(C)c2)C1 +O=c1[nH]c(=O)n(-c2ccccc2)n1Cc1ccccc1 +CN(Cc1ccc(C(F)(F)F)cc1)C(=O)Nc1cnn(C)c1 +COC(=O)c1nn(-c2cccc(Cl)c2)c2nc3ccccc3n12 +Cn1ccnc1SCCNC(=O)c1c[nH]nc1C1CCCCC1 +COC(=O)c1cc(OC)c(OC)cc1NC(=O)c1cccc(OC)c1 +Cc1cc(CN2CC3CCCC(C2)N3C(=O)OC(C)(C)C)no1 +CNS(=O)(=O)c1cc(C(=O)NCCCO)n(C)c1 +CC(=O)NCc1ccc(C(=O)N(C)Cc2ccccc2C)cc1 +COc1ccc(C(C)C(=O)NC(C)c2c(C)noc2C)cc1 +COc1ccc(OC)c(C(C)NC(=O)Cc2cn3ccsc3n2)c1 +Cc1cccc(NC(=O)Cn2nc3ccccn3c2=O)c1C +COc1ccc2c(c1)N(Cc1ccc(CO)o1)CCO2 +COC(CNC(=O)C1CC=CCC1)c1ccccc1C +CC(C)C(=O)Nc1sc2c(c1C(=O)NCC1CCCO1)CCC2 +O=C(NCc1cn(-c2ccccc2)nn1)c1cc(-c2ccccc2)[nH]n1 +O=S(=O)(Nc1ccccc1)c1ccccc1F +CCC1(CNC(=O)NC2CCN(S(=O)(=O)C3CC3)CC2)CCC1 +Cc1ccc(-c2cc(N)c(=O)n(CC(=O)NCc3cccs3)n2)o1 +COc1ccc(NC(=O)CNC(C)c2ccccc2)cc1 +CCCCCNS(=O)(=O)c1ccc(Br)cc1N +CC(C)(C)C(NC(=O)Cn1nc2ccccn2c1=O)C(N)=O +Cn1cc(C#N)cc1C(=O)N1CC(CO)CC(CN2CCOCC2)C1 +CCc1ccc(C(=O)N2CCc3c(nc[nH]c3=O)C2)cc1 +COC(=O)c1cccc(NC(=O)COc2ccccc2F)c1 +COc1cc(-c2noc(-c3ccccc3C)n2)ccn1 +COc1ccc(CC(=O)Cc2ccc(F)cc2)cc1OC +Cn1c(CO)cnc1SCCOc1cccc(C#N)c1 +CCOC(=O)CCCNC(=O)NC1CCSc2c(F)cccc21 +CC1CN(c2nc3c(cc2C#N)CCCC3)CCO1 +CCn1nnc2cc(C(=O)NCC(=O)NC(C)(C)C)ccc21 +Cc1ccc(C(=O)C2CCN(C(=O)C(C)C)CC2)cc1 +CN(Cc1cc(-c2ccccc2)no1)C(=O)CCc1ccco1 +CS(=O)(=O)NC1CCN(C(=O)CCc2ccccc2F)CC1 +Cc1cc(CS(=O)(=O)NCc2cn[nH]c2)no1 +CCc1cc(N2CCC(CC(=O)NC)CC2)n2nc(C)c(C)c2n1 +N#CC1(C(=O)N2CCc3cc(F)ccc3C2)CCC1 +CCOC(=O)N1CCC(NC(=O)c2ccc3[nH]cnc3c2)CC1 +COc1cccc(OC)c1C(=O)NCC1(O)CCOCC1 +COC(=O)C1CCCC1NC(=O)Nc1ccc(S(C)=O)cc1 +CC(=O)Nc1cc(NC(=O)N(C)Cc2cnn(C)c2)ccc1F +CCC(C)NC(=O)COc1c(OC)cc(C)cc1OC +CC(C)n1cc(NC(=O)C2CCN(C(=O)OC(C)(C)C)C2)cn1 +Cc1cccc(OCC(=O)Nc2ccc3[nH]c(=O)c(=O)[nH]c3c2)c1C +CCc1ccc(C(=O)N2CCN(C(=O)Nc3ccccc3)CC2)cc1 +CCOC(=O)Nc1ccc(NC(C(N)=O)c2ccccc2)cc1 +C=CCN1CC2CN(C(=O)c3ccno3)CC2C1=O +CC(NC(=O)C1CCN(C(=O)c2ccco2)CC1)c1ccccn1 +CCCC1(CNC(=O)c2cn(C)nc2C(C)(C)C)CC1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3ncccc3O)cc2)n1 +CCNc1nnc(-c2cc3c([nH]c2=O)CCN(CC)C3)s1 +CCCNC(=O)CNC(=O)c1cc(C2CC2)nc(SC)c1C#N +Cn1ccc(NC(=O)CCCn2c(=O)oc3ccccc32)n1 +CC(NC(=O)C1CCCOC1)c1cccc(N2CCCC2)c1 +NC(=O)c1ccc(C(=O)NCCCN2CCCCCC2=O)cc1 +Cc1cc(CC(C)NC(=O)CN2CCN(c3ncccn3)CC2)[nH]n1 +CC(C)C(NC(=O)c1ccc2cn[nH]c2c1)c1cccs1 +Cc1c(COC(C)C)cccc1NCc1ccc(S(C)=O)cc1 +CCNC(=O)c1cccc(NC(=O)c2ccc(NC3CC3)nc2)c1 +COCC1CCCN(C(=O)c2ccc(C(=O)OC)cc2)C1 +CC1CCC(N(C(=O)c2ccc(OCC(F)F)nc2)C2CC2)CC1 +Cc1cc(C)c2c(c1)OCCCC2n1ncc(C#N)c1N +Cc1ccc(NS(=O)(=O)c2c(C)nc3sccn3c2=O)nc1 +CC(Oc1ccccc1C#N)C(=O)N1CCCC(n2cccn2)C1 +O=C(CN1CCCCC1=O)NCc1ccc(N2CCCCC2=O)cc1 +CC(C)Oc1ccc(CCNC(=O)NCc2ccnn2C)cc1 +CC(=O)NCc1ccc(C(=O)N2CCOC(c3nc(C)n[nH]3)C2)s1 +CCc1ccc(C(C#N)CCC(=O)NC(C)C)cc1 +Cc1ccc(C)c(N(C(=O)Cc2ccc(-n3cnnn3)cc2)C(C)C)c1 +CN(C)C(=O)c1ccc(OS(=O)(=O)N(C)C)cc1 +O=C(Cn1c(-c2nnco2)cc2ccccc21)NCc1ccccc1 +COc1cc(C)c(Cl)cc1NCC(=O)N(C)C +COc1cc(N)cn2cc(-c3ccc4[nH]c(=O)oc4c3)nc12 +O=C(NCc1ccc(-n2cncn2)cc1)c1ccno1 +CC(C)Oc1ccc(NC(=O)CC(C)C(N)=O)cc1 +CC(=O)c1ccc2c(c1)c(=O)oc(=O)n2CC(C)C +CNc1nnc(-c2cc3c(n(C4CC4)c2=O)CCC3)s1 +COc1ccccc1CCNC(=O)C(N)c1ccccc1 +Cc1ccccc1NC(=O)CSc1nc(=O)[nH]c2c1CCCC2 +O=C(C1CC=CCC1)N(Cc1ccc(F)cc1)C1CC1 +CCc1noc(COc2ccccc2C(=O)NCc2ccccc2)n1 +OC(CCNc1ccc(F)cc1)c1ccc2c(c1)OCCO2 +CC(c1nc(-c2cccs2)no1)N1CCOC(Cn2cccn2)C1 +CN(C)C(=O)CN(C)C(=O)C1CC(=O)N(Cc2ccco2)C1 +CC(C)(C)c1nc(COc2cccc(CC(N)=O)c2)cs1 +O=C(COC(=O)c1ccc2c(c1)CCC2)Nc1ccc2c(c1)OCO2 +Cn1cc(NS(=O)(=O)c2ccc(Cl)cc2)c(-c2ccccc2)n1 +CC1CCC(NC(=O)NCCCOCC2CCOC2)CC1 +COc1ccc2c(c1)OCCC(CO)(CO)C2=O +CCS(=O)(=O)c1ccccc1C(=O)N(C)C(C)C +NC(=O)c1nc(-c2ccccc2O)nc2c1[nH]c(=O)n2-c1ccccc1 +COCCC(=O)NCC1Cn2nnc(-c3cccc(F)c3)c2CO1 +CCC(CC)CN(CC)C(=O)Cn1c(C)c(C)sc1=O +COc1ccc(CN(C)c2nc(C)nc3c(C)n(C)nc23)cc1 +CN(Cc1cccs1)C(=O)C1CCC(=O)N(C)C1c1cccs1 +Cc1ccc(C2NC(=O)NC3=C2C(=O)N(Cc2ccco2)C3)cc1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)NC(C)c1cccnc1 +CC1CCc2nc3ccccc3c(C(=O)N3CCNC(=O)C3)c2C1 +COCC1(c2nc(C3CCOCC3)nn2-c2ccncc2C)CC1 +COCc1noc(-c2ccc(N(C)Cc3ccccc3)nc2)n1 +Cc1ccc(N)cc1NC(=O)C(C)Oc1ccc(Cl)cc1 +Cc1ccc(Cl)cc1C1CCc2nc(N)nn2C1C +COC(=O)C(C)(C)NC(=O)CSc1ccc(OC)cc1 +O=C(NCCC(=O)N1CCc2ccc(O)cc2C1)OCC(F)(F)F +COc1ccc(CN(C)C(=O)c2ccnc(OC3CCC3)c2)cc1O +CCc1nn(C(CC)C(=O)NC(C)C)c(=O)c2cc3oc(C)cc3n12 +Cc1csc(-c2cccc(C(=O)N3CCN(C(=O)CO)CC3)c2)n1 +Cn1c(=O)n(CC(=O)N2CCC(c3cn[nH]c3)CC2)c2ccccc21 +O=C(Nc1cccc2[nH]ccc12)N(CC(F)F)C1CC1 +COc1ccccc1C(=O)Nc1ccc2nc(NC(C)=O)sc2c1 +N#Cc1ccccc1NC(=O)c1ccc(-c2cscn2)cc1 +Cc1ccc(NC(=O)NCc2cccc(NS(C)(=O)=O)c2)cc1 +Cc1c(NC(=O)c2cc(C)n(C(C)C)c2C)cccc1C(N)=O +Cc1ccccc1C(=O)Nc1ccccc1C(=O)NCC1CCCO1 +CC(NC(=O)Cn1cnc2cc(F)c(F)cc21)c1ccc(Cl)cc1 +Fc1ccc(CNc2cnn(-c3ccccc3)c2)c(F)c1 +COc1ccc(S(=O)(=O)NCc2ccncc2)c(Cl)c1Cl +CNc1ncnc(Nc2nc3c(C)cccc3s2)c1N +O=C(NCC(O)c1cccc(Cl)c1)c1ccccc1C(F)(F)F +COc1cc(NC(=O)CCCc2nnc3ccccn23)cc(OC)c1 +CCCCNS(=O)(=O)c1cc(Cl)c(C)cc1OC +COc1nn(C)cc1C(=O)NCC(=O)NCCc1ccncc1 +CCCc1nc(N(C)C)sc1-c1csc(NC)n1 +CC(=O)Nc1ccc(Oc2cc(C)nc3ncnn23)cc1 +Cn1cc(-c2nc(C3COCCN3CCc3ccccc3)no2)cn1 +COc1ccc(-c2cc(NCCO)nc3[nH]ccc23)nn1 +COCCNC(=O)Cc1ccc(NC(=O)c2ccccc2)cc1 +COc1cc2c(c(OC)c1OC)C(c1cccc(O)c1)CC(=O)N2 +N#Cc1oc2c(F)cc(Br)cc2c1C1CC1 +COc1ccc2oc(C(=O)NCc3n[nH]c(C)n3)c(C)c2c1 +Fc1ccccc1N1CCCC2(CCN(c3ncccn3)CC2)C1 +COC(=O)C(O)(NC(=O)c1cnccn1)C(F)(F)F +CCCN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1cnccn1 +O=C(Cn1cnnn1)NC1(c2ccc(F)cc2F)CCOCC1 +CC(C)CC(NC(=O)c1cnccn1)c1ccccc1 +CN(C)C(=O)c1cc(-c2ccc(N)cc2)ccc1F +O=C(NCCOc1ccc(F)c(F)c1)c1nc2ccccc2c(=O)[nH]1 +Cc1sc(=O)n(CC(=O)NCc2ccc(OCC(C)C)cc2)c1C +Cn1c(N)c(C(=O)Cc2ccccc2)c(=O)n(C)c1=O +COc1ccc(OC)c(CCNC(=O)N(C)CC2CC2)c1 +Cc1oc(-c2cc(F)cc(F)c2)nc1Cn1cc(CCO)cn1 +CCC(CC)NC(=O)c1cc(S(=O)(=O)NC)ccc1C +NC(=O)c1nn(-c2ccc(Cl)cc2)c2c1CNCC2 +CNC(=O)c1cc(OC)ccc1NC(=O)Cc1c[nH]c2ccccc12 +O=C(C1CCN(c2ccc3ccccc3c2)C1=O)N1CCOCC1 +CC(C)OCCCNC(=O)C1COc2ccccc2C1 +Cc1ccccc1C(=O)NCC(=O)NCCNC(=O)C(C)C +CNC(=O)NCC(=O)NC(C)c1nc2ccccc2n1C(C)C +Cc1cccc(C)c1OC1CN(C(=O)CCc2c(C)noc2C)C1 +CN(CC(F)(F)F)S(=O)(=O)c1ccc(N)nc1 +CC(NC1CCN(C(C)C)C1=O)c1cnc2ccsc2c1 +COc1ccc(O)c(C(=O)NCc2ccc(F)cc2)c1 +O=C1CCc2cc(OCCCC(=O)Oc3ccc(F)cc3)ccc2N1 +CC(C)(C)c1ccc(C(=O)C2CCCN2S(C)(=O)=O)cc1 +CC(C)(C)OC(=O)N1CC2CC1CC2(O)C(F)(F)F +CCc1nc(CC(=O)NCCCc2nc3ccccc3s2)cs1 +CC(C)NC(=O)c1nc(Cc2ccccc2)n(-c2ccccc2)n1 +CCc1ncc(C(=O)N2CCN(CC(O)c3ccccc3)CC2)s1 +Cc1nsc(NC(=O)NCc2ccccc2-n2ccnc2C)n1 +O=C(COc1ccc(NC(=O)C2CC2)cn1)NCc1cccnc1 +Cc1nc(C)c(CC(=O)NCCCN(C)c2ccccc2)s1 +O=C(CCNC(=O)c1ccoc1)Nc1cc(F)cc(F)c1 +C=C(C)CN1CCN(C(=O)c2ccc(F)c(F)c2)CC1 +Cc1cc(C(=O)CCC(=O)Nc2cccc(O)c2)c(C)s1 +CCCn1nnnc1NC(=O)COc1ccc(C)c(C)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cccc(C)c1O +Cc1cc(C)c(NC(=O)c2cccc(F)c2F)c(C)c1 +Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)N(C)C)c(C)c1 +Cc1cn[nH]c1C1CCCN(S(=O)(=O)c2c(F)cccc2F)C1 +Cc1ccc(CCc2nn3cnnc3s2)cc1N +Cc1cccc(NC(=O)CCC(=O)c2ccccc2)c1 +CC(=O)N1CCc2cc(NC(=O)C(C)Oc3ccc(C#N)cc3)ccc21 +CC(Cn1cncc1-c1cnn(C)c1)Oc1ccccc1Cl +Cc1cc(CSc2nnc(-c3ccoc3C)n2C)no1 +O=C(CCNC(=O)c1ccc(Cl)cc1)Nc1nc2ccccc2[nH]1 +N#CCOc1ccc(Cc2nc(CC(=O)NC3CCCC3)no2)cc1 +Cc1cc(C)c2c(=O)n(Cc3c(F)cccc3Cl)c(=O)n(C)c2n1 +c1ccc(COCC2CN(Cc3ccncc3)Cc3ccnn3C2)nc1 +CNC(=O)NCC(=O)Nc1cccc(C(C)OC)c1 +CN(C(=O)Cn1ncc2ccccc2c1=O)c1ccccc1 +COCCNC(=O)CSc1nc2cc(Cl)cc(Cl)c2[nH]1 +CCc1nc(NC(=O)CCN2CCOC2=O)sc1C +Cc1sc2ncnc(OCC(=O)NCCc3ccccc3)c2c1C +COc1ccc(NC(=O)C(C)c2cccs2)cc1NC(C)=O +Cc1nccc(CNC(=O)c2cccc(Br)c2)n1 +CCC(C)NC(=O)COc1cc(C(=O)NC)ccc1N +O=C(Cc1c(F)cccc1Cl)Nn1cnnc1 +CCCCN1CC(C(=O)Nc2nc3c(s2)CCCC3)CC1=O +COc1cccc(CNC(=O)c2ccc3c(c2)N(C)C(=O)CO3)c1 +COc1ccc(C(=O)N2CCC2)cc1S(=O)(=O)N1CCCC1 +O=C(c1ccoc1)N1CCCC(c2nncn2Cc2ccccc2)C1 +CN(Cc1ccncc1)C(=O)NC1CCN(C(=O)C2CCCCC2)C1 +Cn1c(C2CCCCN2C(=O)CN2CCCC2=O)nc2ccccc21 +O=C(Nc1cccc2ccccc12)c1nc(-c2cnccn2)no1 +O=C(Cn1cccnc1=O)NCc1cccnc1OCC(F)(F)F +CCCN1CNc2c(c(=O)[nH]c(=O)n2Cc2ccco2)C1 +O=C1CCCc2[nH]c(=O)c(C(=O)NCCc3ccc(F)cc3)cc21 +CC(C#N)Cn1c(-c2cccc(N)c2)nc2cc3c(cc21)OCO3 +CN(C)C(=O)COc1ccc(-c2ccccc2)cc1Br +Cc1noc(C)c1C(C)NC(=O)NCc1ccccn1 +CN(C)C(=O)CCNC(=O)Nc1cc(C#N)ccc1OC(F)F +CN(Cc1nc2ccccc2s1)C(=O)C1CC(=O)N(CC2CC2)C1 +CCC(C(=O)NC(C)(C)C)N(c1cccc(Cl)c1)S(C)(=O)=O +O=C(CNc1cccc(F)c1)N1CCCc2ccccc21 +COc1ccc2[nH]c3c(NCCCO)ncnc3c2c1 +O=C(COc1ccccn1)Nc1ccc(F)cc1Cl +NC(=O)c1ccccc1NC(=O)c1n[nH]c2ccccc12 +CC(=O)N1CCCC1C(=O)NC(C)CC(O)c1ccccc1 +Cc1cccc(CS(=O)(=O)N2CCN(Cc3ccccc3)CC2)c1 +CCN(CC(C)C#N)C(=O)c1cc(C)n(C(C)(C)C)n1 +N#CCCCn1ccc2ccc(C(F)(F)F)cc2c1=O +COc1ccc(S(=O)(=O)NCc2nnc3ccccn23)c(C)c1C +CCc1c(C(=O)N2CCOCC2)cnn1-c1ccc(OC)nn1 +Cc1nc(CNC(=O)c2cnc(Cc3ccc(F)cc3)s2)cs1 +Cc1ccc(C(=O)C(C#N)c2nnc3n2CCCCC3)cc1F +O=S(=O)(Cc1ccc(F)cc1)NCC(O)C1CCCCC1 +Cc1ccc(NC(=O)c2cnc3c(c2)c(C)nn3C)c(C)c1 +O=C(c1c[nH]c2c(C(F)(F)F)cccc2c1=O)N1CCCCC1 +Cc1noc(C)c1C(C)NC(=O)c1ccc[nH]c1=O +CS(=O)(=O)c1ccccc1C(=O)Nc1ccc(-n2cnnn2)cc1 +Cc1cc(C(=O)N(C2CCC(C)CC2)C2CC2)[nH]n1 +Cc1cccnc1-c1nc(-c2ccccn2)cs1 +CCSc1nnc(-c2ccccc2Cl)n1N +CCc1ccccc1NC(=O)c1c[nH]c2ccccc2c1=O +CC(C)NC(=O)NC1CCSc2ccc(Cl)cc21 +COc1ccc(C(=O)CNC(=O)c2ccccc2C)cc1 +COc1ccccc1C(NC(=O)C1CC=CC1)c1ccccn1 +CNC(=O)c1ccsc1NC(=O)c1cnc2ccccc2n1 +CC(C)c1nc(NC(=O)c2cnc(C3CCCO3)s2)n(C)n1 +N#Cc1ccccc1Oc1ccc(NC(=O)CCC2CCCO2)cc1 +CC(C)Cc1noc(CN2CCOC(C(N)=O)C2)n1 +COc1c(C(=O)N2CCC(c3ccc(F)c(F)c3)CC2)c(C)nn1C +CC(C#N)CN(C)C(C)c1nnnn1-c1ccccc1 +CCC(=O)c1ccccc1OCC(=O)N1CCCCCC1 +Cc1cc(C(=O)N2CCN(Cc3nnc(C4CC4)o3)CC2)c(C)o1 +CC(NC(=O)C1CC2CCCC(C1)C2=O)c1ccccn1 +Cc1cccc(CNC(=O)c2cc3c(=O)n(C)c(=O)n(C)c3s2)c1 +O=C(NCc1noc(-c2ccsc2)n1)c1ccc(=O)[nH]c1 +COCC(O)CN(C)C(=O)c1ccc(N2CCCCCC2)nc1 +COc1ccccc1N1CCN(C(=O)CCc2n[nH]c(N)n2)C(C)C1 +COC(=O)CN1C(=O)CCn2nc(-c3ccc(C)cc3)cc21 +CCC(C(=O)N1CC(c2nc(-c3cccnc3)no2)C1)c1ccccc1 +CC1(CNS(=O)(=O)c2ccc(F)cc2)CCCC1 +COc1cc(C(=O)NC2CCOc3ccccc32)cc2c1OCCO2 +Cc1csc(C(C)N(C)C(=O)c2cnc(N3CCOCC3)nc2)n1 +Cn1cccc1C1COCCN1C(=O)c1cnn(-c2ccccc2)c1 +Cc1ccc(-c2nsc(C(=O)Nc3ccccn3)c2N)cc1 +CC(C)CC1CN(CCC(N)=O)c2ccccc2N1 +Cn1c(N2CCC(O)C2)nc2cc(C(=O)N3CCCCCC3)ccc21 +O=C(Nc1nc[nH]n1)C1CCN(c2ccc(C(F)(F)F)cn2)CC1 +Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)N1CCCC(O)C1 +COc1cc(OC)cc(C(=O)NC2CCCC(C)C2)c1 +CC(C)OC(=O)c1cccc(-c2ccc(CO)o2)c1 +Cc1ccc(OCC(=O)Nc2cccc(-n3cnnn3)c2)cc1 +O=C1NCc2ccc(NC(=O)C3CC(=O)N(C4CCCC4)C3)cc21 +Clc1cccc(-c2nn3c(-c4cnccn4)nnc3s2)c1 +O=C(CCNc1ncnc2ccsc12)NC1CCCC1 +CC(C)(C)Oc1cc(CNC(=O)C2(C)CCCO2)ccn1 +CCNc1cncc(S(=O)(=O)N2CC(C)CC(C)C2)c1 +O=C(Cc1cccs1)Nc1nnc(SCC2CC2)s1 +CCN(CC)c1ccc(CCC(=O)N2CCCC2)cc1N +O=C(CCCCc1ccccc1)Nc1cnn(C2CCOCC2)c1 +O=C(NCCc1noc(C2CCCC2)n1)c1cn2ccsc2n1 +Cc1cc2nc(C3CCCCN3C(=O)c3cnccn3)[nH]c2cc1C +CNC(=O)Cn1c(-c2ccccc2)nn(-c2ccc(OC)cc2)c1=O +CCOC1CCCN(C(=O)c2ccc(N)c(C)c2)C1 +O=C(NCc1cccnc1)Nc1ccc(CCN2CCOCC2)cc1 +COC(=O)c1cc(-c2ccc(F)c(C)c2)nc(N2CCOCC2)n1 +CC(C)Oc1ccc(CCNC(=O)c2cnn3c2SCC3)cc1 +COc1ccc(OC)c(CN(C)C(=O)COc2ccc(Cl)cc2)c1 +CN(Cc1cc(Br)cs1)CC(C#N)CCC#N +CC(Cc1cccc(C(F)(F)F)c1)C(=O)NC(C)C(N)=O +Cc1cc(CN2CCN(C(=O)c3ccc(=O)n(C)n3)CC2)on1 +CC1CCCCC1NC(=O)c1cc2n(n1)CCCO2 +CCCN(CCC)C(=O)c1cnc(-c2cccnc2)nc1N +Cc1noc(CNC(=O)C2CCN(S(=O)(=O)C3CC3)CC2)n1 +O=C1c2cccnc2CN1CC1OCCc2ccccc21 +COc1ccc(OCC(=O)NCC#Cc2ccc(N(C)C)cc2)cc1 +O=C(NCc1cn[nH]c1)c1cc(Br)ccc1F +Cc1ccoc1C(=O)OCC(=O)c1ccc(NC(=O)C(C)C)cc1 +COc1ccc(CNC(=O)Cc2ccc(C)nc2)c(OC)c1OC +CCNC(=O)C1CCCN(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)C1 +Cc1nc(C(=O)N2CCOC(Cc3ccc(F)cc3)C2)cs1 +COc1ccc(OC)c(C(C)NC(=O)Nc2cn[nH]c2)c1 +CCOc1ccc(C2(O)CC(O)(C(F)(F)F)NC(=O)N2)cc1 +CC(C)OCc1ncn2c1CN(C(=O)c1cc(F)cc(F)c1)CCC2 +CCCc1nnc(NC(=O)C(NC(C)=O)C(C)C)s1 +CC(=O)N1CCC2C(=O)N(c3ccsc3)CCOC2C1 +Cc1cc(OCn2ccc(C(=O)NCc3ccco3)n2)ccc1Cl +CCCCOc1cccc(OCC(=O)N2CCOCC2)c1 +Cc1nnc(N2CCC(CNC(=O)OC(C)(C)C)CC2)c(C#N)c1C +Cc1ccccc1-c1noc(-c2ccc(NCc3ccccn3)nc2)n1 +CCOc1ccc(C(=O)NCC2CN(C)CCO2)cn1 +Cc1ccncc1NC(=O)NCc1oc2ccccc2c1C +CCCN(Cc1ccccc1)C(=O)NCc1ncn(C)n1 +CS(=O)(=O)NCc1ccc(NC(=O)Cc2ccccc2F)cc1 +CC1COCCN1Cc1cccc(NC(=O)c2ccccc2Cl)c1 +COc1ccc(NC(=O)c2ccccc2Cl)cc1S(N)(=O)=O +CNC(=O)c1ccc(Cl)cc1NCc1ccccc1C +CCOc1cc(C2c3c(C)n[nH]c3C(=O)N2C)ccc1O +CCc1ccccc1NC(=O)COc1cccc(N)c1 +O=C1CC(COC(=O)c2sccc2Br)CN1 +COC(C)C(=O)NCCNS(=O)(=O)c1ccccc1 +Cn1ccc(C(=O)N2CCc3[nH]nc(Nc4ccccc4)c3C2)n1 +CCCNC(=O)C1CCN(C(=O)NCCC(C)C)CC1 +Cc1noc(C)c1S(=O)(=O)N(C)C(C)CC#N +CCCn1c(=O)n(CC(=O)NCCNC(C)=O)c2ccccc21 +CCn1nc(C(=O)Nc2ccc(C)cc2C)c(=O)c2ccccc21 +Nc1cn2nc(-c3ccc4c(c3)NC(=O)CO4)sc2n1 +Cc1occc1-c1nnc(SCc2ccc(C#N)cc2)o1 +Cc1nc(Oc2ccccc2)cc(N2CCN(C(=O)C(C)C)CC2)n1 +CCN(CCC#N)S(=O)(=O)c1ccc(Br)c(C)c1 +CCOC(=O)C(NC)c1cc(-n2cccn2)ccc1F +COC(=O)C1CCN(C(=O)NCCCC(C)(C)CO)CC1 +CCn1c(C)cc(C(=O)NC2CCC(C)CC2)c1C +COc1cc(Br)c(NC(=O)CC2CCCO2)cc1OC +Cc1nc(C2CCCN2C(=O)c2ccc3c(c2)ncn3C(C)C)no1 +COc1ccc(NC(=O)CCCc2cccs2)cc1OC +CC(O)CNC(=O)NCc1cnn(-c2ccccc2)c1 +CC(=O)c1ccc(Nc2ncnc3c2NC(=O)CN3)cc1 +OCc1cc(C(O)CN2CCOCC2)ccc1O +CCc1nc(-c2nn(-c3ccc(F)cc3)c(=O)[nH]c2=O)no1 +NC(=O)CSc1ccccc1NC(=O)Cc1cn2ccsc2n1 +Cc1sc(=O)n(CC(=O)Nc2cccnc2OC(C)C)c1C +Cc1cc(NC(=O)CNC(c2ccccc2)c2ccccn2)no1 +CC(C)c1ccc(-c2cnncc2Br)s1 +CCOc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CC +O=C1NCCN1c1cccc(C(=O)N2CCc3ccc(F)cc32)c1 +Cc1ccc(C(=O)Nc2cnn(CC(F)(F)F)c2)cc1C +O=C(c1ccc(S(=O)(=O)NCc2ccccn2)o1)N1CCCC1 +COCc1noc2c1CN(S(=O)(=O)C1CC1)CC2 +CC(C)N(C(=O)CCc1ccsc1)C1CCOCC1 +O=C(Nc1cccs1)Nc1ccccc1Cc1nc(C2CC2)no1 +Clc1cnc(NC2CCC(n3cnnc3)CC2)nc1 +CC(C)c1ccsc1C(=O)N(C)CC(=O)N(C)C +Cc1cn2cc(C(=O)NCc3cnn(Cc4ccccc4)c3)ccc2n1 +CC(C)NC(=O)C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +CC(C)(C)NC(=O)c1cc(S(N)(=O)=O)ccc1N +Cc1cc(NC(=O)Cn2ccn(-c3ccccc3)c(=O)c2=O)no1 +COC(=O)c1ccccc1NS(=O)(=O)c1ccccc1F +COC(=O)CCN(C)C(=O)Nc1ccccc1OC +CC(C)CCNC(=O)c1cc(Cl)c2c(c1)OCCCO2 +O=C(CC1(O)CCCCC1)N1CCc2cc(F)ccc2C1 +N#Cc1cccc(NC(=O)NCc2ccncc2)c1 +COC(=O)c1onc(-c2c(Cl)cccc2Cl)c1C(=O)OC +O=C(c1cccnc1Nc1ccccc1F)N1CCC1 +O=C(N1CCCC(c2ccn[nH]2)C1)C12CC3CC(CC(C3)C1)C2 +CC1CCCN(C(=O)CSc2ncnc3sc4c(c23)CCC4)C1 +CCC1CCC(CNC(=O)Cn2c(C)csc2=O)CC1 +O=C(c1ccco1)N(CC1CCCO1)c1ccncc1 +Cc1cncc(C(=O)N2CCC3C2CC(=O)N3c2cccnc2)c1 +COc1ccccc1-c1nc(-c2cn(-c3ccccc3)nn2)no1 +Cc1nc(-c2cnn(C)c2)sc1C(=O)NC(C(N)=O)C(C)(C)C +COC(=O)C1(NC(=O)C2CCCN(c3ncccn3)C2)CCCCC1 +CC(O)CNC(=O)C1(c2ccc(Br)cc2)CC1 +COc1ccccc1CC(=O)Oc1ccc(-n2cnnn2)cc1 +c1ccc(-c2cn3nc(NCCN4CCOCC4)sc3n2)cc1 +N#CCCN(Cc1cccnc1)c1cc(C#N)ccn1 +Cc1ncsc1C(=O)N1CCCC(C(=O)N(C)C)C1 +COCC(=O)Oc1ccc2c(=O)c(Cl)coc2c1 +CCn1cc(C(=O)NCCC(=O)Nc2cccc(C)n2)cn1 +COc1ccc(S(=O)(=O)n2cnc3ccccc32)cc1C +CCNC(=O)CN(C)C(=O)c1cccc(Br)c1 +CN(Cc1ccccn1)C(=O)c1cc2ccccc2o1 +O=C(c1cc(Cl)c2c(c1)OCCO2)N1CCCCCC1 +Fc1ccc(CSc2nnc3n2CCCCC3)cc1F +CC(=O)N(C)C1CCN(C(=O)CCOC(C)CC(C)C)CC1 +Cc1ccc(OC(C)C(=O)c2cccs2)c(N)c1 +CCS(=O)(=O)c1ccc(C(=O)N=c2sccn2C)cc1 +O=C(NCCOc1ccc(Br)cc1)c1cnn[nH]1 +CC(C)n1nnnc1-c1ccccc1NC(=O)N1CCC(C#N)CC1 +COc1ccc(C(=O)Nc2c(C)cc(Br)cc2C)nn1 +CC(C)CC1(CNC(=O)NCc2ccc(C(N)=O)o2)CCCC1 +O=C(NCc1ccccn1)c1ccc2c(=O)n3c(nc2c1)CCCC3 +Cc1noc(C)c1S(=O)(=O)N(CC(C)O)c1ccccc1 +CCCCNC(=O)C1CCCN(Cc2sc(N(C)C)nc2C)C1 +COCCN(Cc1cccs1)C(=O)c1ccccc1C#N +CCNC(=O)c1ccc(CNC(=O)CSc2ccc(F)cc2)cc1 +CNC(=O)c1cncc(C=Cc2nc(-c3cc4ccccc4o3)no2)c1 +O=C1CCCCCN1CCNc1nc2ccccc2o1 +Cc1ccc(C(=O)NCC(=O)OCC(=O)NC2CCC(C)CC2)cc1 +Cc1ccc(C(=O)N(C)CCc2ccccc2)c(C)n1 +CNc1nc(CNC(=O)Nc2ccc3c(c2)CCN3C(C)=O)cs1 +Cn1ncc2c1ncn1nc(-c3ccn(C(F)F)n3)nc21 +COc1cc(COc2ccc(C#N)cc2)cc(OC)c1OC +COc1ccc(-c2cc(CN(C)C(=O)C3CC3)no2)c(OC)c1 +Cc1ncc(CNS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)s1 +Cc1n[nH]c(C)c1NC(=O)c1ccc(F)cc1F +Cc1ccccc1C(NC(=O)CCNC(=O)c1cnccn1)C(C)C +COC(=O)Cn1cnc2cc(OC)c(OC)cc21 +CC(C)c1csc(C(=O)N(C2CC2)C(C)c2ccccn2)n1 +O=C(c1c2c(-c3cccnc3)ncnc2n2ccccc12)N1CCCC1 +Cc1n[nH]c(C)c1NS(=O)(=O)c1ccc2c(c1)C(=O)NCC2 +CN(CC(=O)N1CCN(C(=O)C2CC2)CC1)CC(F)(F)F +CCc1ccccc1NS(=O)(=O)c1ccc(F)c(NC(C)=O)c1 +Cc1ccc(OC2CCN(C(=O)CCC3CCCCC3)CC2)nn1 +COc1ccc(C(=O)Nc2nc(-c3ccc(C)cc3)n[nH]2)cc1OC +Cc1cccc(CC(=O)Nc2ccc(OCC(N)=O)cc2C)c1 +Nc1cccc(-c2nc(-c3ccccc3F)no2)c1 +Cc1csc(C(NC(=O)NCC2(O)CCCCCC2)C2CC2)n1 +COc1ccc2c(c1OC)C(c1ccc(=O)[nH]n1)NCC2 +NC(=O)N1CCCN(C(=O)C2(c3cccc(F)c3)CCC2)CC1 +O=C(NCc1cscn1)c1occc1COc1ccccc1 +COC(=O)CN1C(=O)C(C)(C)c2cc(NC(=O)C3CCC3)ccc21 +CC(C)(O)CN(Cc1ccccc1)C(=O)NCc1ccsc1 +COC(=O)c1ccc2c(c1)CCN(C(=O)OC(C)(C)C)C2 +CCN(CC)C(=O)CCC(=O)Nc1ccc(C)c(F)c1 +Cc1nc(-c2ccc(F)cc2)sc1C(=O)N1CCCC1 +COC(=O)COC(=O)c1c2c(nc3ccccc13)CCC2 +O=C(c1cc(Cl)c2c(c1)OCO2)N1CCN(c2cnccn2)CC1 +COC(CNS(=O)(=O)c1ccccc1F)c1ccsc1 +COc1ccc(C(O)CNc2ccccc2OC)c(OC)c1 +COC(=O)C(C)NC(=O)c1cc(NC(C)=O)ccc1F +CN1C(=O)c2ccccc2NC12Cc1ccccc1C2 +CCN(Cc1ccc2c(c1)OCO2)S(=O)(=O)c1cccc(C#N)c1 +COC(=O)CNC(=O)N1CCCC1c1cc(C)on1 +CCCCSc1nc(-c2ccco2)nc2c1c(=O)n(C)c(=O)n2C +Cc1cc(C)n(-c2ccc(NC(=O)NCCC(=O)NC(C)C)cn2)n1 +O=C(NCc1nc2ccccc2[nH]1)c1ccc(C(F)(F)F)nc1 +COc1cccc(S(=O)(=O)CCN2CC(n3cc(C)cn3)C2)c1 +Fc1cnc2oc(C(Cl)(Cl)Cl)nc2c1 +O=C(Nc1cc(-c2ccccc2)ns1)C1CCCO1 +Brc1ccc(NCC2CCOC2)cc1 +Cc1ccc(C(=O)N2CCOc3c(N)cccc32)cc1C +CCCC(=O)Nc1ccc(C(=O)Nc2cccc(C(C)=O)c2)cc1 +N#Cc1ccc(S(=O)(=O)N2CCC(Nc3ccccc3)C2)cc1 +O=C(CCCn1cncn1)N(Cc1cccs1)c1ccc(F)cc1 +CC(C)C(C(=O)Nc1ccc(Br)cn1)N1CCCC1=O +CS(=O)(=O)N1CCC(NC(=O)c2cc(F)ccc2F)CC1 +COc1ccc(C)cc1NCCC(O)c1ccccc1 +Cc1cccc(N(CCC(N)=O)C(=O)C(C)Sc2ccccn2)c1 +CC12CCC(C(=O)N3CCCc4ccccc43)(CC1=O)C2(C)C +CCNc1nc(SC(C)c2nc(C)no2)nc2ccccc12 +Cc1cnc2c(c1)nc(-c1ccccc1C)n2CCO +CCCOC(=O)CSc1nc2ccc(NC(C)=O)cc2s1 +CC1CCC(N(C)C(=O)CSc2nnc(CO)n2C2CC2)CC1 +Cc1cccc(C(=O)NC(C(N)=O)c2ccccc2)c1O +Cc1cc(NC(=O)C(C)Oc2ccccc2C#N)no1 +CC(C)c1nnc(SCC(=O)c2ccc[nH]2)n1C1CC1 +Cc1ccc(C(=O)N2CCN(Cc3cscn3)CC2)c(=O)[nH]1 +Cc1ccc(C)c(-n2nnnc2SCC(=O)NCc2ccco2)c1 +CCC(C)(C)C(=O)N1CCC(C(=O)Nc2cc(C)ccn2)CC1 +CCc1c(C(=O)Nc2ccc(CNC(N)=O)cc2)[nH]c(C)c1C(C)=O +CCNC(=O)C1CCN(c2ccccc2Br)C1=O +N#Cc1cnn(-c2ccnc3cc(Cl)ccc23)c1N +CCCS(=O)(=O)NCC(c1ccccc1Cl)N1CCOCC1 +O=c1[nH]cnc2ccc(-c3ccc(F)c(CO)c3)cc12 +COc1ccccc1-c1nnc(SCCCc2cnn(C)c2)o1 +COC(=O)CN(Cc1cccc(-n2cccn2)c1)C(C)C +CC(C)(C)OC(=O)CSc1nnnn1CC(F)(F)F +Cc1ccc(SCC(=O)N(CCC#N)c2cccc(Cl)c2)nc1 +COCCCN(C)C(=O)Nc1ccc(C(=O)N2CCCCCC2)cc1 +C=CCNC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +O=C(CNC(=O)c1cccc(Cl)c1)NCCc1ccc(F)cc1 +COc1ccccc1NC(=O)CSc1nc(-c2cccnc2)n[nH]1 +CCNC(=O)C(NC(=O)c1ccc(F)cc1)C(C)C +COC(=O)c1cccc(NCc2nc(-c3cccc(OC)c3)no2)c1 +COc1cc(F)c2c(c1)C(C1CCCN1C(C)=O)NCC2 +Cc1ccccc1CC(=O)Nc1sc(C(C)C)cc1C(N)=O +COc1ccc(C(=O)N(CCO)C2CCCC2)cc1 +Cc1nc(CC(=O)N2CCCCC2CCn2cccn2)cs1 +Cc1cccc(Nc2ccccc2C(=O)NCC(N)=O)c1C +Cc1ccc(NC(=O)NC2CCCCNC2=O)cc1OCC(F)F +O=C(Nc1cccc(Cn2cccn2)c1)c1ccc(F)c(F)c1 +C=C(C)CN(CC)C(=O)CNS(=O)(=O)c1cn(C)cn1 +CCn1nc(C)c2c1cnn2CC(=O)N1CCC(C)CC1 +OC(CN(Cc1ccco1)Cc1cccs1)c1ccc(F)cc1F +CC(=O)N1CCN(C(=O)c2ccc(F)cc2F)CC1 +CCCC(O)c1cc(CC)cc2c1NC(=O)C2CC +COCn1nc(CO)cc1-c1ccc(Cl)cc1Cl +COc1ccc2c(c1)OCC(CNC(=O)c1cn3cccnc3n1)C2 +Cc1c(C#N)nnc2c(Br)c(-c3ccccc3)nn12 +COc1cc(NC(=O)Cc2cccs2)c(C(=O)N(C)C)cc1OC +CC(C)Cc1cc(C(=O)Nc2c[nH]c3ccccc23)on1 +CN(C)C(=O)Oc1ccc2ccccc2c1Br +COc1cccc(CC(=O)N2CCN(Cc3ccnn3C)CC2)c1 +O=C(Cc1coc2cc3c(cc12)CCC3)NCC(F)(F)F +CCc1nnc(-c2ccc(NC(=O)C3CCCCC3)cc2)o1 +Cc1c(NCC(=O)NC2CCCCC2)cccc1C(N)=O +CCS(=O)(=O)N1CCN(c2ccc(O)cc2)CC1 +CCc1cc(Sc2cn[nH]n2)nc(-c2ccncc2)n1 +CC(C)COCCNC(=O)Nc1ccc2c(c1)OCCO2 +CC(C)(C)c1ncc(C(=O)Nc2c[nH]c3ccccc23)cn1 +CC(C)c1cccc(N(C)CC(=O)NCCC#N)c1 +Fc1cccc2c1CCNC2C1Cc2ccccc2N1 +CC(C)c1nnc(NC(=O)c2ccc(=O)n(C)c2)s1 +O=C(Nc1ccc(N2CCCCC2)c2ccncc12)c1ccco1 +CCC(C)Cc1c(C)sc2nc(CCn3cc(C)cn3)[nH]c(=O)c12 +CCCNC(=O)c1ccc(-c2ccc(OC)cc2)nc1N +COCCNC(=O)C1(c2ccc(F)cc2F)CCOCC1 +O=C(NCCc1ccccc1)C1CCCN1C(=O)Nc1ccccc1 +O=C(CSc1nnc2n1CCCN2)c1ccccc1 +Cc1ccc(C)c(N(CC(=O)N(C)C)S(C)(=O)=O)c1 +C=CCNC(=O)C1CCN(c2cccc(F)c2)C1=O +C#CC(OC(=O)CC(C)c1ccccc1OC)C1CC1 +COc1cccc2cc(C(=O)Nc3ccc4occc(=O)c4c3)oc12 +Cc1ccc(NC(=O)N(C)CCC#N)cc1S(C)(=O)=O +CC(=O)NC1CCCN(C(=O)NCc2ccc(-c3ccn[nH]3)cc2)C1 +COCc1nc(C(=O)N2CCCc3cccc(C)c32)cs1 +CC(C)Sc1ccc(C(=O)C2CCCCN2)cc1 +Cc1ccc(Cl)cc1NC(=O)NC(C)C(C)CO +CCOc1cc2c(cc1NC(=O)c1cc(C3CC3)on1)OC(C)C2 +OCc1cc2c(cc1OCc1ccsc1)OCO2 +COc1cccc2c1OCC(NC(=O)N(C)C(C)c1ccccn1)C2 +C=C(C)CN(CC)C(=O)Cn1ncc2ccccc2c1=O +Cc1cc(C(=O)Nc2ccccc2NC(=O)Cc2cccs2)on1 +O=C(NCC(=O)N1CCCc2ccccc21)c1cc(C2CC2)[nH]n1 +COC(=O)c1ccc(NC(=O)NCc2ccco2)cc1F +CCn1c(NCCO)nc2c1c(=O)[nH]c(=O)n2CC(C)C +Cc1nccn1-c1ccc(CNC(=O)Cc2ccc[nH]2)cn1 +COCCCN1C(=O)CCC2CN(C(=O)c3ccc[nH]c3=O)CCC21 +Cc1cc(C)c2c(c1)C(NCCCN1CCOCC1)CCO2 +CC(CC(=O)NCCc1cccc(O)c1)C(C)(C)C +CCCCn1c(SC(C)C(=O)c2ccc(C)cc2)n[nH]c1=O +Cc1cccc(S(=O)(=O)N2CCC3OC(C)CC3C2)c1 +O=C(NC(c1ccccc1)c1ccncc1)C1CCOC1 +CC(C)CCNC(=O)C1CCN(c2ccccc2)C1=O +COC(=O)c1cc(-c2cc(Cl)c(C)cc2O)nn1C +O=C(c1cc2cc(F)ccc2[nH]1)N1CCOC(CO)C1 +Cn1cc(CNc2cccc(-n3cccc3)c2)cn1 +COCCOC(=O)CN1C(=O)CNc2cc(Cl)ccc21 +CC(C)C(NC(=O)Nc1ccncc1)c1cccs1 +Cc1cc(C)c(S(=O)(=O)Nc2cccc(C(=O)N(C)C)c2)c(C)c1 +O=C(Nc1cnc(-c2ccccc2)nc1)c1cc2c([nH]c1=O)CCC2 +O=C(CCc1nnc(C2CCCC2)o1)Nc1cnc2ccccc2n1 +Cc1noc(C(C)Oc2ccc3ccc(=O)oc3c2)n1 +CCOC(=O)c1[nH]c(C)c(C(=O)N(Cc2ccccc2)C(C)C)c1C +CC(=O)Nc1ccc(F)c(NC(=O)C2CCCO2)c1 +OCC1CCN(c2ccc(C(F)(F)F)cc2)CC1 +N#Cc1cccc(-c2cn(Cc3c(F)cccc3F)nn2)c1 +COc1cccc(NC(=O)CNC(=O)c2cc(C)n(C)n2)c1 +CCN(Cc1noc(C)n1)C(=O)Nc1cc(NC(C)=O)ccc1C +O=C(NCCNC(=O)C1CC1)c1cnn(-c2ccccc2Cl)c1 +CN(C)C(=O)CC1(CC(=O)Nc2cccc(Cl)c2)CCCC1 +CCCc1nc(N(C)Cc2cnc(NC)nc2)c2cnn(C)c2n1 +Cc1cc(-c2nn3c(CC(C)C)nnc3s2)no1 +O=C(CCc1nc2ccccc2[nH]1)NCc1ccc(Cl)cc1 +NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)NC1CCCCC1 +COC(=O)C(C#N)CC(=O)c1ccc(OC)c(F)c1 +Cc1nc(CC(=O)OCc2cccc(C(N)=O)c2)cs1 +Cc1cc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)sc1C +CC(NS(=O)(=O)Cc1ccc(F)cc1)C(=O)N1CCCCC1C +CC(c1cc(F)ccc1F)N(C)S(=O)(=O)c1cccs1 +Cc1cnc(NC(=O)CSc2nc3ccccc3o2)s1 +O=C(Nc1nc[nH]n1)c1ccc2ccccc2c1O +CS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C#N)c1 +O=C(NC1CC1)C1COC2(CCCCC2)N1C(=O)c1ccccc1F +CCC(C)(C)NC(=O)Cn1cc(C(F)(F)F)ccc1=O +Cc1cc(C)c(C(=O)Nn2c(C)nc3ccccc3c2=O)cc1C +N#Cc1ccc(N2CCN(S(=O)(=O)N3CCCCCC3)CC2)nc1 +COc1cc(Cl)c(C)cc1NC(=O)N1CCOCC1CO +COC(C)CN(C)C(=O)c1cc(-c2cccnc2)[nH]n1 +COCc1c(C(=O)Nc2ccc(F)cc2)nnn1-c1ccccc1 +CN(C)c1ccc(NC(=O)Cc2cccc3cccnc23)cn1 +CN(C(=O)CC1C=CCC1)c1nc2ccccc2s1 +O=C(NCC(=O)N1CCOCC1)c1ccc(Br)cc1 +Cc1cc(CNc2cccc(C(=O)N(C)c3ccccc3)c2)no1 +Cn1nc(C(=O)OCc2cc(-c3ccc(F)cc3F)on2)ccc1=O +Cc1ccc(NC(=O)NCCNC(=O)C2CC2)c(F)c1 +CC(C)C(=O)Nc1cc2c(cc1C(=O)C(C)C)OCCO2 +O=C(Nc1ccc(N2Cc3ccccc3C2=O)cc1)c1cccnc1 +O=C(Nc1ccc(OC(F)F)cc1)c1ccc(=O)[nH]c1 +CC(C)c1ccc(S(=O)(=O)NC(C#N)c2ccco2)cc1 +Cc1c(C(=O)Nc2ncccc2O)nnn1-c1ccc(F)cc1 +COc1ccccc1NC(=O)C(Sc1nncn1C)C(C)C +c1cc(-c2nc(C3CCOC3)no2)c2[nH]ccc2c1 +Cc1ccc(C(=O)N2CCC(N3CCCC3=O)CC2)cc1O +O=C(Cc1ccc[nH]1)NCc1ccc(Oc2ccc(F)cc2)nc1 +Cc1cccc(OCCCN2CCCCS2(=O)=O)c1 +CC(=O)N(C)CC(=O)Nc1ccc(Cl)cc1OCC(F)(F)F +CC(=O)Nc1nc2ccc(C(=O)N3CCCCC3)cc2s1 +O=C(NCCc1cccnc1)NCc1cn(-c2ccccc2)nn1 +CCc1cccc(CC)c1NC(=O)Nc1ccc2c(c1)CC(=O)N2 +CC(C)(O)CN(Cc1ccccc1)C(=O)Nc1ccc2c(c1)CCO2 +Cc1noc(NC(=O)c2cccc(S(C)(=O)=O)c2)n1 +Cn1cc(C(=O)OCC2COc3ccccc3O2)c(C(C)(C)C)n1 +Cc1cc(C)n(CCCNS(=O)(=O)c2cccs2)n1 +CCC(C)n1ncc(C(=O)Nc2ccc(F)cn2)c1C1CC1 +CCc1onc(C)c1NC(=O)NCC1(C(=O)N(C)C)CCCC1 +O=c1[nH]c2ccc(Cn3cc(C4CCOC4)nn3)cc2[nH]1 +NC(=O)c1cccc(OCC(=O)N2CCCC2Cn2cccn2)c1 +C=CCn1c(SCC(=O)Nc2cc(C)on2)nnc1C1CC1 +COc1ccccc1N1CCN(C(=O)C2CC2(Cl)Cl)CC1 +COc1ccc(Cc2nnc(SCCn3cccn3)o2)cc1 +COc1ccc(C(=O)N(C)C)cc1NCc1cccc(F)c1 +Cc1nc2cc(NCCC(N)=O)c(N)cc2s1 +N#CCCN(CCC#N)c1ncnc(Nc2cccnc2)c1N +NC(=O)c1cnc(NCCc2nnc3ccccn23)c(Cl)c1 +Cc1ccc(C(=O)N2CCOCC2)cc1NS(C)(=O)=O +CCCCNC(=O)CSc1nnnn1-c1ccc(C)cc1 +CC(CNS(=O)(=O)Cc1ccon1)N1CCOCC1 +N#CCCN(Cc1ccccn1)S(=O)(=O)c1ccc(F)cc1 +CC(C)(C)C(=O)Nc1cccc(C(=O)N2CCCC2C(N)=O)c1 +CN(Cc1ccccn1)C(=O)c1cc(F)c(Cl)cc1Cl +Cc1cccc(S(=O)(=O)C(C)C(=O)NCc2ccccc2)c1 +Cn1c(NCCO)nc2c1c(=O)n(Cc1ccccc1F)c(=O)n2C +Nc1ccc(S(=O)(=O)NCc2ccccc2Cl)nc1 +N#Cc1ccccc1OCC(=O)c1ccc2c(c1)OCCO2 +CN1CCN(C(=O)CNc2ccc3nnnn3n2)CC1 +Fc1ccc(-c2nn3c(C4CC4)nnc3s2)cc1 +O=C(Cc1ccccc1Br)NCCCn1ccccc1=O +Cc1cc(OCCn2cc(Br)ccc2=O)ccc1N +O=C(Nc1ccc(-c2nc[nH]n2)cc1)c1cccc(OCC(F)F)n1 +COC(=O)CC(NC(=O)Nc1ccncc1)c1ccc(SC)cc1 +CCOc1cccc(NC(=O)CCn2nc3ccccn3c2=O)c1 +Cc1occc1C(=O)OCc1cccc(S(=O)(=O)N(C)C)c1 +CCc1nc(CNc2cccc(C(C)OC)c2)no1 +CCCNC(=O)C1CCN(C(=O)NC2CCCc3ccccc32)CC1 +Cn1cc(CC(=O)Nc2nc3c(s2)COCC3)c2ccccc21 +CC(C)CCNC(=O)NCCC(=O)NC1CCCC1 +COc1ccccc1COC(=O)C1CCc2cn[nH]c2C1 +CCN(CCC(=O)OC)C(=O)Cc1cn2ccccc2n1 +O=C(NCc1cccc(Br)c1)c1ccc2[nH]cnc2c1 +CCc1nnc(CSc2nccn2-c2ccccc2)o1 +COc1ccc(S(=O)(=O)N(C)Cc2csc(C)n2)c(C)c1 +COc1cccc2ccc(-c3ccc(N)nc3)nc12 +CCS(=O)(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +O=C1OCCN1CCn1cc(-c2cccc(Cl)c2Cl)nn1 +CC(C)c1noc(CCNC(=O)c2cccc(OC(F)F)c2)n1 +Cc1cccc(NS(=O)(=O)c2ccc(C#N)cc2)c1 +CCCc1sc(C(=O)N(CC(N)=O)C(C)C)cc1CC +CC(C)CN(CC(N)=O)C(=O)c1ccc(C#N)cc1 +C=CCOc1ccccc1CN1CCNC(=O)CC1c1ccccc1 +Cn1ccsc1=NC(=O)CNc1ccc(C#N)cc1 +COc1cc(OC)cc(C(=O)NCc2ccc(-n3cccc3)cc2)c1 +CCCCN(C)C(=O)c1ccccc1Br +Cc1cc(C(=O)NC2CCCN(S(C)(=O)=O)C2)n(C)n1 +COc1ccc(CNC(=O)N2CCOCC2CC(C)C)cc1 +CC(=CC(=O)OCC(=O)N1CCCCCC1)c1ccccc1 +COc1ccc(CNC(=O)N2CCC(O)(C3CCC3)C(C)C2)cc1 +CN(Cc1ccccc1F)C(=O)c1ccc(-n2ncc(C#N)c2N)cc1 +CCC(=O)N1CCCN(C(=O)NCCc2cccc(Cl)c2)CC1 +O=C(Cc1ccc(Cl)cc1)NC1C(c2cncnc2)CC(O)C1O +CN(CCN1CCOCC1)C(=O)Nc1ccccc1N(C)C +NC(=O)COc1ccccc1-c1nc2c(cnn2Cc2ccncc2)[nH]1 +CCN(Cc1cccc(NC(=O)N2CCCC2)c1)C(C)=O +COc1ccc2oc(CN3CCN(c4cnn(C)c4)C(=O)C3)cc2c1 +COc1cccc2c1OCC(CNS(=O)(=O)N(C)C)C2 +COCc1ccccc1NCc1nc(-c2ccccc2)no1 +N#CC(C(=O)c1cccc2c1OCO2)c1nc2ccccc2[nH]1 +COC(=O)c1ccc(C(=O)Nc2ccccc2F)cn1 +O=C(Nc1cn[nH]c1)c1c(Cl)cccc1Cl +CSc1ccc(CN(C)C(=O)COc2ccc(C#N)cc2)cc1 +COc1ccc(NC(=O)N2c3ccccc3CC2C(N)=O)c(OC)c1 +COCc1cccc(NC(=O)c2ccc(Cn3ccnc3)cc2)c1 +O=C(CCn1cnc2ccccc21)NCc1nc(-c2ccncc2)no1 +CCC(C)C(=O)N(Cc1ccc(C(N)=O)cc1)C1CC1 +CCC(CC)C(=O)NCCN1CCN(C(=O)OC)CC1 +Cc1ccc(OCC(=O)Nc2ncccc2CO)cc1 +COc1ccc(F)cc1CN1CCc2cncnc2C1 +C=CCN(Cc1cccs1)C(=O)c1ccc(NC(C)=O)s1 +Cc1nc2c(N(CCCO)C(C)c3ccccc3)ncnc2o1 +Cc1cc(N(C)CCCO)ccc1Br +Cc1cc(C(=O)Nc2nnc(-c3ccncc3)s2)no1 +CNC(=O)COC(=O)c1ccccc1OCc1cscn1 +CC(NC(=O)NCc1ccnc(OC2CCC2)c1)C1CN(C)CCO1 +CC(C#N)(NC(=O)CNc1ccccc1-n1cccn1)C1CC1 +O=C(Cc1c[nH]c2ccc(F)cc12)Oc1cccc(-n2cccn2)c1 +Cc1c(NC(=O)C2CC2)cccc1C(=O)NCC(C)C +CC(C)c1cc(C(=O)N2CCNCC2C(=O)N2CCCC2)cs1 +CC(=O)N1CCC(NS(=O)(=O)c2ccc(C)c3ncccc23)CC1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C(F)(F)F)cc2)c1C +Cc1cccc(OS(=O)(=O)c2c[nH]c(C(=O)N3CCCC3)c2)c1 +CCCCCN1C(=O)c2ccccc2S1(=O)=O +Cc1ccnc(NC(=O)CCCn2cnc(-c3ccccc3)cc2=O)c1 +CN(C)c1nc(N)nc(CSc2ccc(F)cc2)n1 +CCCn1nccc1NC(=O)c1cc(C)ccc1C +CCC(=O)c1ccc(S(=O)(=O)Nc2ccc(C)cc2O)cc1 +Cc1c(NCc2cccnc2)cccc1C(=O)N(C)C(C)c1ccco1 +CC(C)C(NC(=O)c1ccco1)C(=O)NCCO +COc1ccc(C(C)(C)C)cc1C(=O)CCN1CCOCC1 +CS(=O)(=O)NC1CCCN(c2ccc(C#N)c(C(F)(F)F)c2)C1 +CCOC(=O)C1=C(C)Nc2nnnn2C1c1ccccn1 +COC(=O)c1c(C)[nH]c(C(=O)NC2CCN(C(C)=O)CC2)c1C +CCc1cccc(C)c1NC(=O)NCCc1cccs1 +O=c1[nH]c2ccc(S(=O)(=O)N3CCc4ccccc4C3)cc2s1 +CCCCc1nnc(-c2c(Cl)c(CC)nn2C)o1 +CN(Cc1cnn(C)c1)C(=O)Cn1ccc(-c2ccsc2)n1 +CC(=O)Nc1ccc(C#CCNC(=O)NC(C)C)cc1 +CN(Cc1ncnn1C)C(=O)CCSc1ccccn1 +CCC(C)n1ncc(C(=O)NCC(C)(C)N2CCOCC2)c1C1CC1 +Cc1cc(Cn2cnc3sc(C)c(C)c3c2=O)no1 +COc1cccc(C(=O)Nc2ccc(F)c(F)c2F)c1 +COc1cc(CCC(=O)Nc2nc(C)cs2)on1 +Cn1c(SCc2ccccc2)nc2sccc2c1=O +Cc1csc(N2CCN(S(=O)(=O)c3cccnc3)CC2)n1 +COC(=O)Nc1cccc(NCc2noc(C(C)C)n2)c1 +CCN(Cc1c(C(C)C)nn(C)c1N1CCOCC1)CC(C)C#N +O=c1c2ccnn2cnn1Cc1nc(-c2cccs2)no1 +CCOc1cc(C(=O)Oc2ccc3cn[nH]c3c2)ccc1OC +CCC(C)C(NC(=O)Cc1coc2c(C)c(C)ccc12)C(N)=O +CCCn1c(SCc2nc3ccsc3c(=O)[nH]2)n[nH]c1=O +COc1cccc(CNC(=O)CCc2ccc3ccn(C)c3c2)c1 +CC(C)COc1cccc(-c2ncc(C(N)=O)c(N)n2)c1 +COc1ccc(NC(=O)NCc2nnnn2-c2ccc(C)cc2)cc1 +COc1ccc(CCNC(=O)Cc2noc3ccccc23)c(OC)c1 +CC(C)(C)C(=O)N1CCC(n2cc(C3(O)CCCC3)nn2)CC1 +CC(OCC(F)(F)F)C(=O)N1CCCCCC1c1ccco1 +CC(C)N(C)S(=O)(=O)c1ccc(C(=O)OCC(F)(F)F)cc1 +CCNC(=O)C(C)NS(=O)(=O)c1ccccc1N +O=C(Nc1cccc2cccnc12)C1CC1(Cl)Cl +O=C(NCC#Cc1ccccn1)c1ccn(C2CCCC2)n1 +COC(=O)C1NCC(C)(C)c2c1cc(F)c(F)c2F +Cc1ccc2cnn(CCC(=O)N3CCCCCC3)c2c1 +COc1ccc(Cc2nnc(NC(=O)c3snnc3C)o2)cc1 +Cc1ccc(OCC(=O)N(C)c2ccc(S(C)(=O)=O)cc2)c(C)c1 +Cc1c(CCC(=O)NCc2ccco2)c(=O)oc2c(C)c(O)ccc12 +Cc1ccc2ncc(C(=O)Nc3ccc(S(C)(=O)=O)nc3)n2c1 +CC(Oc1ccc(C(C)(C)C)cc1)C(=O)N1CCN(CCO)CC1 +Cc1ccc(N2CC3CCC(C2)N(Cc2ccccc2)C3=O)nn1 +O=C(c1ccc(Cl)cn1)N1CCC(CO)C(O)C1 +CC(NC(=O)C1COCCO1)C(=O)NC1CCCC1 +Cn1cc(Cn2nnc3c(cnn3-c3ccccc3)c2=O)cn1 +Cn1cc(CCNS(=O)(=O)c2ccc(-c3ccccc3)cc2)cn1 +COC(=O)CSc1[nH]c(NC(C)=O)c(C(N)=O)c1C(N)=O +CN1CCN(S(=O)(=O)c2ccc(Br)cc2)CC1 +COc1ccc(OC(=O)CCn2ccccc2=O)cc1 +O=C(CCc1ccncc1)N1CCC(C(=O)N2CCCCC2)CC1 +COCc1noc(CNC(=O)c2oc3cc(C)ccc3c2C)n1 +CCOC(=O)CN(C)S(=O)(=O)c1c(C)sc2ccccc12 +COc1cc(OC)c(OC)cc1CNS(=O)(=O)c1ccccc1 +CC(C)c1nc(N2CCCCC2C)sc1CO +CCC(Sc1nc(-c2ccccc2)n[nH]1)C(=O)Nc1cc(C)on1 +Cn1nc(-c2cccnc2)c2c1CCCC2CC#N +O=c1c(Cl)c(N2CCOCC2)cnn1-c1nc2ccccc2[nH]1 +CNC(=O)c1ccc(NC(=O)CCC=Cc2ccccc2)cc1 +Cn1cccc1C(=O)COc1ncnc2c(Cl)cc(Cl)cc12 +O=C(c1ccc(CS(=O)(=O)c2nccs2)cc1)N1CCCC1 +N#Cc1ccnc(N2CCN(C(=O)c3ccsc3)CC2)c1 +O=C(CCOc1cccc(Cl)c1)NCCCO +Cc1c(C(=O)OC(C)C)nnn1-c1nonc1N +OCc1nnn(-c2cccc(F)c2)c1-c1cccc(Cl)c1 +CCNc1c(COc2ccccc2Br)c(C)nn1C +COc1cccc(CNC(=O)c2scnc2C)c1 +OCC1OC(Sc2nc3ccccc3[nH]2)C(O)C(O)C1O +COc1cc2c(cc1O)C(c1cc(F)cc(C#N)c1)NCC2 +O=C(NCc1ccc(Oc2cccnc2)c(F)c1)N1CCCC(O)C1 +CN(C(=O)NCCNC(=O)c1ccc(F)cc1)C1CCCCC1 +COC(=O)c1[nH]c2ccccc2c1NS(=O)(=O)c1ccc(F)cc1 +O=C(Nc1ccc2c(c1)OCCCO2)N1CCc2ccccc2C1 +Nc1nc2ccccn2c1S(=O)(=O)NC1CCCC1 +N#CCCn1cnc2c(NCc3ccccc3)ncnc21 +Cc1n[nH]c(CC(=O)N2CCC(Cc3cccc(CO)c3)C2)n1 +O=C(Cc1ccccc1Cl)Nc1cccc(O)c1 +CC(=O)c1ccc(OC(C)C)c(NC(=O)C2CCCO2)c1 +O=S(=O)(NCC1CCCC1)c1ccc(F)c(F)c1F +Cc1cc(C(=O)N2CCc3cc(F)ccc3C2)c2c(=O)[nH]n(C)c2n1 +N#Cc1ccc(C2NC(N)=Nc3nc4ccccc4n32)cc1 +Cc1nn(C)c2ncc(C(=O)Nc3nc(C4CC4)cs3)cc12 +Cn1ccc(C(=O)NC2CCN(c3c(F)cccc3F)C2=O)cc1=O +O=C(Cn1ccnc1)NCc1cccc(C(=O)NCc2ccco2)c1 +CN1CC(C(=O)Nc2ccc(OCc3ccccc3)cc2)CC1=O +OC(CN1CCOC(c2nccs2)C1)c1ccccc1F +Cc1cc(=O)c(OCC(=O)Nc2cccc3ncccc23)c[nH]1 +CNC(=O)c1cn[nH]c1C1(C)CCCN(C(=O)c2ccc(F)cc2)C1 +O=C(CNC(=O)CC12CC3CC(CC(C3)C1)C2)NCC(=O)NC1CC1 +CC(C)c1nc(CN2CC(Oc3ccc(F)cc3)C2)co1 +COC1CCN(S(=O)(=O)c2cccc(Br)c2)CC1 +Cc1cc(C(=O)N2CC3(C)CC2CC(C)(C)C3)cnc1C +O=C(CCOCC(F)(F)F)Nc1c(F)cccc1F +CCC(C)(C#N)NC(=O)CCc1ccc(C(=O)OC)cc1 +COc1ccc(-c2cn(-c3ccc(Cl)c(N)c3)nn2)cc1F +Cc1occc1COC(=O)c1scnc1C1CC1 +Cc1ccnc(CC(C)N(C)C(=O)Cn2cc(C)c(=O)[nH]c2=O)c1 +COc1c(C)cnc(CNS(=O)(=O)N2CCCCCC2)c1C +NC(=O)c1ccnc(-c2ccccc2OCc2ccccc2)c1 +NC(=O)c1ncc(OC2CC2)cc1Br +O=C(Nc1cnn(Cc2cccnc2)c1)c1cc(Cl)ccc1Cl +COCc1ccccc1NC(=O)NCc1ccnc(OC(C)(C)C)c1 +CCOc1ccc2nc3c(cc2c1)CN(CCOC)C(=O)O3 +Cc1cc(C(=O)NCCCO)c(C)n1C(C)c1ccccc1 +CN(CCCNS(=O)(=O)c1ccccc1)S(C)(=O)=O +COCc1nc(N2CCOCC2)sc1CC#N +CN(C(=O)CSc1nccn1C)C1(C#N)CCCCC1 +CCNc1nc(-c2cc(C)oc2COC)cs1 +O=C(CCC(=O)c1cccs1)Oc1ccc2cn[nH]c2c1 +CC(C)COC1CCN(C(=O)c2cccc(-c3ccoc3)c2)CC1 +CC(C(=O)NC1CC1)N(c1ccc(F)cc1)S(C)(=O)=O +O=C(OCC(=O)N1CCCC1)c1ccc(NC(=O)C2CC2)cc1 +CCCCc1c(SCC)c(N)[nH]c(=O)c1C#N +CC(=O)C(NC(=O)CN(C)Cc1ccc(C#N)cc1)C(C)C +Cc1cnc(NC(=O)CC2CC3CCC2C3)s1 +CNS(=O)(=O)c1ccc(C(=O)NCCCn2cccn2)cc1 +COC(=O)c1ccc(NCc2csc(-c3cnn(C)c3)n2)c(C)c1 +CC(C)c1cc(N2CCN(C(=O)C3CC3)CC2)nc2nncn12 +O=C(NCc1cccnc1-n1ccnc1)c1cn2ccsc2n1 +Cc1nn(C(C)C)c(C)c1NC(=O)c1cc2sccc2n1C +O=C(NCC1(c2ccc(F)cc2)CCOCC1)c1cc(Cl)ccn1 +CC(C)CNC(=O)c1ccc2c(c1)C(=O)c1cnccc1-2 +Cc1cc(C)n(-c2ccc(CCNCc3ccc(C(N)=O)cc3)cc2)n1 +Cc1cc(-n2ccc(C)c(C#N)c2=O)ccc1Br +Cc1cc(C)c(C(=O)N2CCC(NC(N)=O)CC2)c(C)c1 +Cc1nnc(SCC(=O)NC2CCCCC2)n1-c1ccc(F)cc1 +CCOC(=O)CN(C(=O)Cc1ccccc1C)C1CC1 +CN(Cc1cccs1)c1cccc(Cl)c1CO +CC(=O)N1CCCC1C1CCCN1c1ccnc(-c2ccccc2)n1 +Cc1sc(CCNC(=O)Cn2ccnc2)nc1-c1ccccc1 +COC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(C)cc1 +CC(Cn1cccn1)NS(=O)(=O)c1ccc2c(c1)OCCO2 +CCCC(=O)N1CCCC1c1cc(=O)[nH]c(N)n1 +Cc1cc(NC(=O)C(Cc2ccccc2)NC(=O)c2ccco2)ccn1 +O=C(Cc1ccc2ccccc2n1)c1ccccc1F +CCC(OC)C(=O)Nc1ccccc1C(=O)NC1CC1 +O=S(=O)(NCc1cnn(Cc2ccccc2)c1)c1cccs1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)N2CCCC2(C)C)c1 +CCNC(=O)CCSc1nnc(-c2ccco2)o1 +O=C(Cn1cccnc1=O)N1CCCC(OCc2ccccc2)C1 +CCOC(=O)C(O)(CC(=O)Nc1cc(F)ccc1C)C(F)(F)F +Cc1ccc(NC(=O)CN2CCSc3ccccc32)nc1 +Cc1sc(-c2ccco2)nc1C(=O)N1CCCC1C(=O)N(C)C +O=C(NC1=Nc2ccccc2C2=NCCN12)C1CC1 +Cc1csc(NC(=O)CSc2nc3ccccc3c(=O)n2C)n1 +O=S(=O)(NC1CCSc2ccc(F)cc21)c1ccccc1 +Cc1ccn2cc(C(=O)NCc3nnc4ccccn34)nc2c1 +CCC(c1ccccc1)c1n[nH]c2c1CN(Cc1ccncc1)CC2 +Cc1ccsc1C(O)CNC(=O)NCc1cccs1 +Cc1cc(C(=O)OC2C3CCOC3C2(C)C)c2c(C)nn(C)c2n1 +CC(=O)c1cccc(NC(=O)c2csc3c2CCCC3)c1 +CC(C)(C)Nc1nc(=O)c(Cc2ccc(F)cc2)n[nH]1 +O=c1c2oc3ccccc3c2ncn1CC(O)c1cccc(Cl)c1 +CCCc1nnc(NC(=O)c2cc3cccc(OC)c3o2)s1 +COc1ccc(S(=O)(=O)N(C)C(C)C#N)c(OC)c1 +Cc1n[nH]c(C)c1CCC(=O)Nc1cc(N2CCCC2)ncn1 +CCC(C)(C)NC(=O)CS(=O)(=O)c1ccc2ccccc2c1 +Cc1ccc(NC(=O)CCNC(=O)c2c[nH]c(C(C)C)n2)nc1 +CCn1nnnc1NCc1c(F)cccc1Cl +CCOCCNC(=O)Nc1ccc(-c2cc[nH]n2)cc1 +COc1cc(N2CCC3OCCC(c4nnc(C)o4)C3C2)ncn1 +CCC(=O)Nc1ccc(NC(=O)CNc2cccc(C)c2)cc1 +Cc1nc2ccccc2nc1-n1nc(C)c2cc(N)cnc21 +CC(C)C(=O)NCCNC(=O)C1(C)Cc2ccccc2C(=O)O1 +COc1ccc(F)c(NC(=O)c2cccc(-n3cnnn3)c2)c1 +CC(=O)N1CCC(NC(=O)CCCSc2ccccc2)CC1 +Cc1cccc2c(CO)cn(CC(=O)NCC(C)C)c12 +CCOc1ccc(CNc2nc(C)cc(=O)[nH]2)cc1OCC +COc1ccccc1CCC(=O)Nc1ccc(C(C)=O)cc1 +C#CCOC(=O)Cc1csc(-c2ccsc2)n1 +CCC1COCCN1C(=O)c1ccc(-n2ccnn2)cc1 +CC1CCCCC1NC(=O)N1CCC2(CC1)OCCO2 +CCC(CO)NS(=O)(=O)c1ccc(F)cc1C +CCCNC(=O)CCNC(=O)Nc1ccc(C(=O)NC)cc1 +COc1cc(C)ccc1OCC(=O)Nc1ccc2c(c1)OCO2 +COC(=O)c1ccc(C(=O)N2CCOc3ccc(F)cc32)cc1 +Cc1csc(NC(=O)Cc2c(F)cccc2Cl)n1 +COc1ccc(-c2cc(CNC(=O)C3CCC(=O)N3)no2)cc1OC +CC1CCN(C(=O)CNC(=O)c2ccco2)CC1 +Cc1ccccc1-n1ncc(C(C)NC(=O)CC2CC2)c1C +Cc1ccc(NC(=O)c2cn(C)c3ccccc3c2=O)cc1 +Cc1noc(CCCC(=O)Nc2cccc(Oc3ccccc3)c2)n1 +Cc1cc(C)nc(N2CCCC(C(=O)NCCc3ccco3)C2)n1 +CC(C)n1c(=O)[nH]c2cc(C(=O)NCC3CCCO3)ccc2c1=O +OCc1cn(-c2ccc(NCc3noc(C4CC4)n3)cc2)nn1 +CC1CCC(NC(=O)N2CCN(c3ncccc3C#N)CC2)CC1 +COc1cccc(NC(=O)CSc2ncn(-c3ccccc3)n2)c1 +COc1ccc(CCCNC(=O)N2CCOCC2C)cc1 +Cc1cc(NC(=O)Cn2ncc(N3CCOCC3)cc2=O)on1 +COc1cc(NCc2c(C)nn(-c3ccccc3)c2C)cc(OC)c1 +CN(Cc1cccnc1)c1ccc(C#N)c(C(F)(F)F)c1 +CNC(=O)NCC(=O)Nc1ccc(-c2cn3cccnc3n2)cc1 +Cc1ccc(C)c(NC(=O)CN(C)C(=O)CNC(=O)c2ccco2)c1 +CCCCc1ccc(NC(=O)C2CCCN2S(C)(=O)=O)cc1 +COC(CC1C(=O)OC(C)(C)OC1=O)c1ccccc1 +COCCc1nc(CNC(=O)c2cc(C(C)C)nn2C)no1 +NS(=O)(=O)c1c(Br)cc(F)cc1Br +O=C(c1cc2ccccc2[nH]1)N1CCN(Cc2ccncc2)CC1 +CCc1nc2ccccc2n1Cc1nc2ccccc2n1CC(N)=O +CCc1onc(C)c1NC(=O)N1CCC(Oc2ccccc2)CC1 +CC1CC1C(=O)Nc1ccc(C(=O)Nc2ccc(Cl)cn2)cc1 +O=C(NCC(=O)N1CCNCC1)C1CCCCC1 +CC(=O)c1ccc(S(=O)(=O)Oc2ccc(C)cc2)cc1 +CNC(=O)COc1ccc(NC(=O)C(C)c2cccs2)cc1 +Cc1nsc(NC(C)c2cc3ccccc3o2)n1 +CC(=O)NCCn1ccnc1-c1ccc(F)c(F)c1F +CNc1nnc(-c2c(C)cc(C)n(C(C)C)c2=O)s1 +CCCNC(=O)c1ccc(NC(=O)c2cc(C)n(C(C)C)c2C)cc1 +COc1ccc(Br)cc1NC(=O)N(CCO)C(C)C +Cc1ccccc1CCNC(=O)C(C)Oc1ccccc1C(N)=O +O=C(NCCc1nc2ccccc2n1C(F)F)NC1CC1 +CNc1ncc(CN(C)Cc2cc(=O)[nH]c3ccccc23)cn1 +Cc1nc(-c2ccc(C(=O)Nc3ccc4c(c3)OCCO4)cc2)no1 +CC(C)n1cc(Br)cc1C(=O)N(C)CC1CCCO1 +CC(C)c1cc(NC(C)c2ccncn2)n2nccc2n1 +Nc1nc(NCc2ccccc2)nc(-c2cc(F)cc(F)c2)n1 +CC1CC1C(=O)Nc1cccc(CNC(=O)OC(C)(C)C)c1 +CSc1ccc(NC(=O)Cn2cc(N)cn2)cc1 +NC(=O)CSc1ncnc2cc(-c3ccc(F)cc3)sc12 +CCCCOCC(=O)N1Cc2cnc(CC(C)C)nc2C1 +CCCC(C)(CO)NC(=O)Nc1cc(F)ccc1-n1cccn1 +c1coc(-c2nnc(-c3ccc(-n4ccnc4)nc3)o2)c1 +COCCn1cc(NC(=O)NC2(C)Cc3ccccc3C2)ccc1=O +COc1ccc2cc(C(=O)NCCc3cccs3)c(C)nc2c1 +CC(C)Cc1noc(CN2CCN(S(N)(=O)=O)CC2)n1 +O=C(NCc1nnc2n1CCC2)c1ccc(-n2cccc2)cc1 +O=S(=O)(NCc1ccccn1)c1cncc(Br)c1 +CN1CCOC2CN(C(=O)NCC3CN4CCCCC4CO3)CC21 +COCCN1CCN(C(=O)c2cnc3ccc(C)cn23)CC1 +CCOC(=O)c1ccc(N(C)CC(=O)NC(C)C)nc1 +N#Cc1cc(-c2cc(F)cc(F)c2)cc2c1NCCC2 +NC(=O)c1ccc(C(=O)OCc2ccccc2Br)cc1 +O=C(NCC(O)(c1cccs1)C1CC1)Nc1ccc2c(c1)OCO2 +C=CCNC(=O)CNC(=O)CNC(=O)c1ccc(Cl)cc1Cl +Cc1nc(N2CCC(O)C2)c2c3c(sc2n1)CCCC3 +CN(Cc1ccncc1)C(=O)c1c(Cl)ccc(Cl)c1Cl +CC1C(=O)Nc2c(Cl)cc(C(O)Cc3cccs3)cc21 +C#CCOC(=O)c1cc(Cl)ccc1Br +CC(C(=O)NCC1CC1)n1ccc(C(F)(F)F)n1 +COCc1c(Br)cccc1NC(C)=O +CC(C)(C)NC(=O)c1cnn2c(-c3ccc(F)cc3)ccnc12 +O=C(COC1CCCC1)NCCCn1nc2ccccn2c1=O +O=C(CCNC(=O)c1ccccc1)NCCc1nc2ccccc2[nH]1 +CNC(=O)C1Cc2ccccc2CN1C(=O)CCC1CCCC1 +CCCc1nnc(NCC(=O)c2ccc(Cl)cc2)s1 +CCS(=O)(=O)N1CCC(NC(=O)CNC(=O)C2CCCC2)CC1 +CCOc1cccc(C(=O)NC(C)c2ccccc2)c1 +CCN1C(=O)C(Cc2nc3ccccc3c(=O)n2C)c2cc(C)ccc21 +O=C(N1CCCC1)N1CCC2OCCCC2(COCC2CC2)C1 +CC(C)N(CC(F)(F)F)C(=O)c1ccc2c(c1)CCN2 +Cc1cc(N2CCC3(CCCN(C4CCCCC4)C3=O)C2)nc(N)n1 +CCCCc1nnc(SCc2ccc(F)cc2C#N)n1N +Cc1csc(Cc2nc3scc(-c4ccccc4)c3c(=O)[nH]2)n1 +Cc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccco2)cc1 +c1cncc(CN(Cc2nnnn2C2CC2)CC2CCCO2)c1 +Cc1occc1C(=O)Nc1cccc2ncccc12 +CCN(CC(=O)N(C1CC1)C(C)C1CC1)c1ccccc1 +CC(C)(C)OC(=O)NC1CCCN(C(=O)c2cccnc2F)C1 +CN(C)S(=O)(=O)NCCS(=O)(=O)c1ccc(C(C)(C)C)cc1 +Cc1csc2c(=O)n(CCc3cn[nH]c3)cnc12 +Cc1noc(C)c1COc1ccc(C(=O)Nc2cccc(F)c2)cc1 +Cc1[nH]ncc1CCCNC(=O)c1ccc(Cl)cc1O +CCCN(C)c1nc2c(c(=O)[nH]c(=O)n2C)n1C +Cc1ccc2ncc(C(=O)NCCCNc3ccccc3)n2c1 +Cc1ccc2c(n1)sc1c(=O)n(CC(C)O)cnc12 +Cc1ccc(C(=O)Nc2cc(C3CCCC3)nn2-c2ccccc2)cn1 +O=C(NCc1ccccc1)NCC(O)c1cccc2ccccc12 +COc1ccc(C(=O)NCc2coc(-c3cccs3)n2)c(OC)c1 +CC(C)n1nnnc1COc1ccc(C(=O)NCC(=O)N(C)C)cc1 +CN(C1CCCCC1)S(=O)(=O)c1cccc(C(=O)NC2CC2)c1 +Cc1ccc(-c2nc(-c3ccc4c(c3)oc(=O)n4C)no2)cc1 +CC(CNC(=O)OC(C)(C)C)N(C)C(=O)c1ccc(F)cc1 +O=C(CCC1CCCCC1)N1CCCC1c1nc(C2CC2)no1 +COC(=O)C(CC(C)C)NC(=O)CC1CCCC1 +CCC(OC)C(=O)NCc1cccc(C(=O)NC)c1 +N#Cc1cccc(COC(=O)c2ccc(N3CCOCC3)nc2)c1 +Cc1cccc(C)c1NC(=O)NCc1ccc(-n2cncn2)cc1 +COc1ccccc1SCCS(=O)c1ccccc1 +COc1ccc(NC(=O)CCn2c(=O)n(C)c3ccccc32)cc1 +COc1ccc(NC(=O)Nc2ncccc2C)cc1 +CC(=O)NCCNC(=O)CCc1ncc(-c2ccc(F)cc2F)o1 +CCSc1ccc(NC(=O)NCCc2ccncc2)cn1 +COc1ccc(C(=O)CCNc2ccccc2F)cc1F +COc1ccc2c(c1)CN(C(=O)Cc1c[nH]c3ccccc13)CC2 +CN(C1(C#N)CCCCC1)S(=O)(=O)c1cccs1 +CCOc1ccc(C(=O)N2CCC(C(N)=O)CC2)nn1 +Cc1cc(O)c(C(C)C)cc1NC(=O)c1ccn(C)c(=O)c1 +CCS(=O)(=O)Nc1cccc(Cn2cccn2)c1 +COC(=O)c1sc(NC(=O)CCc2cnn(C)c2)nc1C1CC1 +COc1ccccc1-c1cc(C(=O)NC2CCN(C(C)=O)CC2)no1 +O=C(Nc1nc(-c2cccnc2)cs1)c1cnn2c1OCCC2 +C#CCN1CCN(S(=O)(=O)c2ccc(F)c(C)c2)CC1 +Cn1c(NCCNC(=O)c2ccccc2)c(C#N)c(=O)n(C)c1=O +Cc1cc(Cl)ccc1-n1c(C)ccc(C#N)c1=O +C#CCNC(=O)c1cc(-c2ccccc2OC)nn1CCC +Cc1ccccc1NC(=O)C(C)NC(=O)c1ccc(F)cc1 +Cc1nc(C(=O)N2CCCN(S(C)(=O)=O)CC2)cs1 +COc1cc(NS(C)(=O)=O)ccc1N1CCCCC1=O +CCOC(=O)CSc1ccc(-c2nc(CC)no2)cn1 +O=C(Nc1ccc(F)cc1)N1CCOCC1C1CC1 +Cc1nc(CN)nc(-c2ccc(OC3CCCC3)cc2)n1 +COc1ccccc1C1(C(=O)NCC2(O)CCOCC2)CC1 +Cc1ccc(CC(=O)NCCNc2nnnn2-c2ccccc2)cc1 +COc1cc(C#N)ccc1OCC(=O)NCCc1ccccc1C +CCC(=O)N1CCN(C(=O)NCCCCC(=O)OC)CC1 +CCCN1CCN(S(=O)(=O)c2c(C)noc2C)CC1 +CC(C)CCN1CCN(C(=O)c2cnc(C3CCCO3)s2)CC1 +Cn1ccnc1SCC(=O)NCC1CCCCO1 +COc1ccc(C(NC(=O)NCc2cnn(C)c2)C(C)C)cc1 +N#Cc1ccc(C(=O)NCCOCC(F)(F)F)cc1 +Cc1cc2nc(-c3ccccc3)c(=O)n(CCO)c2cc1C +CCn1cc(NC(=O)N(C)C(C)c2ccccc2)cn1 +CCCc1cc(C(=O)NCc2csc(-c3ncccn3)n2)ccn1 +CN(Cc1nc(-c2ccc(Cl)cc2)no1)S(C)(=O)=O +CCC(C(=O)N1CCC(CO)CC1)c1ccccc1 +CCS(=O)(=O)NCCNC(=O)N1CCC(C)CC1C +Cc1ccc(Cl)c(OC(C)C(=O)Nc2oncc2C)c1 +Cc1nc(C(=O)N2CCCC2c2nnc3n2CCCCC3)cs1 +O=C(CSc1ccccc1F)Nc1ccc2c(c1)OCO2 +CCC(C)n1ncc(C(=O)N(C)Cc2ccccc2Cl)c1C1CC1 +Cc1cc(NC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c2ncccc2c1 +Cc1nnc(CSc2nccn2Cc2ccccc2)o1 +O=C(CCNC1=NS(=O)(=O)c2ccccc21)Nc1ccccc1F +CCN1C(=O)N(c2ccccc2)C(C)(O)CC1(C)C +CC(C)c1noc(CN2CCCC2c2noc(C3CC3)n2)n1 +Cc1nc(C(F)(F)F)ccc1C(=O)NCCCN1CCCC1=O +COc1ccccc1CNc1cc(OCC(C)C)nc(C)n1 +NS(=O)(=O)c1ccc(NC(=O)C2CCCO2)cc1Br +COc1ccc(NC(=O)C2CC2)cc1OCc1ccc2ccccc2n1 +COC(CNC(=O)c1ccc(N(C)C)cc1)c1cccc(F)c1 +Cc1ccccc1N(CC(=O)NC(C)c1ccccc1)S(C)(=O)=O +CCOC(=O)C1CCN(S(=O)(=O)c2ccc(C)c(C)c2C)CC1 +O=C(Cn1nc(-c2ccc(F)cc2)ccc1=O)NCC1CCCO1 +Cc1ccsc1CN(C)C(=O)C1(c2ccccc2)CC1 +CN(C(=O)CNc1ccn(-c2ncccc2Cl)n1)C1CCCCC1 +Nc1nccnc1C(=O)Nc1nc(-c2ccc3c(c2)CCO3)cs1 +COc1cccc(CC(=O)N2CCN(CC(N)=O)CC2)c1 +COC(=O)C(C)CN(C)C(=O)CNc1ccccc1 +CC(=O)NCCNC(=O)CCSc1ccc(C)cc1 +CC(C)(C)c1nnc2sc(CCc3cccc(O)c3)nn2c1=O +CC(C)n1nc(-c2ccc3c(c2)OCO3)c2c1CCCC2=O +Cc1csc(-c2ccc(CNC(=O)C3CCOC3)cc2)n1 +Cc1occc1C(=O)NCCNC(=O)OC(C)(C)C +CCC(=O)Nc1ccc(C(=O)Nc2cccnc2)cc1 +CCn1nc(CNC(=O)c2ccc(F)cc2)c2ccccc21 +COc1ccc(Cc2nc3ncc(C)cc3[nH]2)cc1 +Cc1cscc1C(=O)N(C)CCN(C)C(=O)OC(C)(C)C +CC(NC(=O)OC(C)(C)C)C(=O)N(C)Cc1cccnc1 +CCc1noc(CC)c1CNC(=O)CNC(=O)c1cccc(Cl)c1 +COc1cc(C(=O)N2CCOC(C)C2)ccc1OC(F)F +CC1CCN(c2cc(NC(=O)CCCc3ccccc3)ncn2)CC1 +Cn1nccc1C(=O)N1CCN(Cc2cscn2)CC1 +Cc1noc(C)c1CC(=O)NC1CCCC(OCC(F)(F)F)C1 +CCN(CC)C(=O)CCC(O)c1ccc(C)c(N)c1 +CCOC(=O)C1CCCN(C(=O)Nc2ccc(F)c(F)c2)C1 +CCCc1noc(CN(C)Cc2cnn(-c3ccccc3C)c2)n1 +CC(CO)NC(=O)c1cccc(S(=O)(=O)N(C)c2ccccc2)c1 +COc1cccc(C(=O)NCCCn2c(C)nc3ccccc32)c1F +O=S(=O)(Cc1cc(-c2ccccc2)on1)c1nccn1C1CC1 +O=C(NCC(O)c1ccc(Cl)cc1)Nc1cccnc1 +OC(COc1ccc(Cl)cc1)(c1ccccc1)c1cccnc1 +O=C(Nc1ccc(-n2cnnn2)cc1)N1CCc2sccc2C1 +CNC(=O)c1sc2nc(C)nc(N3CCCCC3)c2c1C +O=c1[nH]nc(-c2ccccc2)nc1Cc1ccc2c(c1)OCO2 +Cc1nc(C#N)c(N2CCN(C(=O)CN(C)c3ccccc3)CC2)o1 +O=C(NCC1COCCO1)C1CC1c1ccco1 +Cc1c(C)c(C(=O)NC2CC2)n(Cc2ccccc2F)c1C +COc1cc(Cc2c(O)n[nH]c2N)c(OC)cc1C +CC(C)(C)c1ccc(CNCC(=O)NCc2ccco2)cc1 +COCc1ccc(CNC(=O)Nc2cc(OC)ccc2F)cc1 +COC(=O)N1CCC(CNC(=O)c2cc(C3CC3)on2)CC1 +Cc1cc(C)n(-c2ccc(C(=O)N3C(C)COCC3C)cc2)n1 +CSc1ccc(NCc2nnc(C(C)(C)C)o2)cc1F +O=C(NCc1cnn2ccccc12)Nc1ccc2c(c1)OCO2 +CC(C)C(NC1=NS(=O)(=O)c2ccccc21)C(=O)N(C)C +Cc1ncc(N)cc1C(=O)Nc1c(F)cccc1F +CC(C)c1ccsc1C(=O)N1CCN(C(=O)C2CCCO2)CC1 +NC(=O)C(NCC1Cc2ccccc2O1)c1ccccc1 +COc1ccnc(NC(=O)C(NC(=O)CC(C)C)C(C)C)c1 +CCOc1ccccc1OCCc1nc(C)c(C(C)=O)s1 +O=C(c1cnc(C2CCCO2)s1)N1CCOCC12CCC2 +Cc1noc(C)c1S(=O)(=O)N1CCCc2cc(N)ccc21 +CN(CCc1ccc(F)cc1)C(=O)NCc1ccncc1 +Cc1cc(F)ccc1NC(=O)c1cc(C2CC2)on1 +O=C(Cn1ccnc1)NC(Cc1ccccc1)c1ccccc1 +CCN(CC)C(=O)CCC(=O)Nc1ccc2[nH]ncc2c1 +Cc1nc(C(=O)N(C)Cc2csc(-c3ccccc3)n2)cs1 +O=C(Cn1c(=O)oc2cccnc21)Nc1ccccc1 +CCc1oc(-c2ccc3c(c2)OCCO3)cc1C(C)=O +Cc1ccc(C#N)cc1NC(=O)NC1CCOc2ccccc21 +Cc1[nH]nc(O)c1C(c1ccc(C(F)(F)F)cc1)C(C#N)C#N +Cn1cc(C2CCCN2C(=O)c2ccn(-c3ccc(F)cc3)n2)cn1 +O=C(c1ncn(CC(O)c2ccc3c(c2)OCO3)n1)N1CCCC1 +N#Cc1ccsc1NC(=O)CSc1nncs1 +CC(C)C(NC(=O)c1cccs1)C(=O)N1CCN(CCO)CC1 +O=C(Nc1ccc(Cl)cc1C(F)(F)F)N1CCCC(O)C1 +CCCOc1ccccc1NC(=O)c1cscn1 +CC(NC(=O)Cc1cccc(O)c1)C(O)c1ccc(F)c(F)c1 +NC(=O)CCCC(O)c1ccc2c(c1)OCCCO2 +COC(=O)c1cc(-c2ccccc2O)nc2cc(C3CC3)nn12 +Cc1[nH]ncc1CCCNC(=O)NCc1ccccn1 +Cc1ccsc1-c1nccn1CCC(=O)Nc1nccs1 +CCOc1ncnc2c1CN(CC(=O)NC1CCCCNC1=O)CC2 +Cc1ccc(CN(C(C)C)S(=O)(=O)CCC2CCCO2)s1 +CCN(CC)S(=O)(=O)CC(=O)Nc1ccccc1F +CNc1ccc(NS(=O)(=O)c2ccccc2C)cc1F +Cc1n[nH]c(C)c1NC(=O)c1cccc(NCC(C)(C)C)c1C +Cc1cc(NC(=O)c2nc3ncc(Br)cn3n2)n(C)n1 +COC(C)c1cccc(NC(=O)NC2C3CCC(C3)C2CO)c1 +Cc1cc2occ(CC(=O)Nc3ccnc4ccnn34)c2cc1C +N#CCCCCS(=O)(=O)N1CCC(c2ccccc2)CC1 +N#CCSc1nsc(SCC#N)c1C#N +CCSc1nc2c(c(=O)n1-c1ccccc1OC)SCC2 +COc1ncccc1N(C)C(=O)c1ccc2ccc(Cl)cc2n1 +COCCNC(=O)COc1cccc(Br)c1 +CC(Oc1ccccc1)C(=O)Nc1cnc(-c2cccnc2)nc1 +O=C(CCCc1ccccn1)N1CCc2cc(F)ccc2C1 +Cc1ccc2c(c1)N(C(=O)Cc1cccc(OCC#N)c1)CC2 +CC(NC(=O)Cc1ccc(Cl)cc1)c1ccc(-n2cncn2)cc1 +O=C(NCc1ccc2c(c1)OCO2)c1noc2c1CCCCC2 +Cc1nn(C)c(C)c1C(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2 +COc1ccc2c(c1OC)C(=O)N(c1ccc(F)cc1)C2 +CCCn1nnnc1CSc1nnc(-c2c[nH]c3ccccc23)o1 +CCOC(=O)NCCC(=O)Nc1cccc(C#Cc2ccccc2)c1 +CCSc1cc(Cl)ccc1C(=O)NC(C)C(=O)NC +CCn1cc(NS(=O)(=O)c2cn(C)nc2C)c(C(=O)NC)n1 +CCn1c(CCNC(=O)c2ccc(C)c(C)c2)nc2cccnc21 +N#Cc1cc2c(cc1Cl)Sc1nccn1S2(=O)=O +COCCOC(=O)Nc1cccc(NC(=O)c2cc(C)ccc2O)c1 +O=C(NCCc1ccccn1)c1cccnc1-n1cccn1 +O=C(C1CC2CCC1O2)N1CCC(c2c[nH]c3ncccc23)CC1 +CC(=O)c1c(F)cccc1N1CCC(Cc2cccnc2)CC1 +O=C(c1ccccc1-c1ncc[nH]1)N1CCCC(c2ccn[nH]2)C1 +COc1ccccc1CCNC1=NC=NC2=NC=NC21 +O=C(CC1CC1)NCc1noc(Cc2ccccc2)n1 +Cc1sc(=O)n(CC(=O)N(C)Cc2cccc(F)c2)c1C +CCOCCCNC(=O)NC1CC1c1cccc(Cl)c1 +Cc1ccc(S(=O)C(C)C(=O)Nc2cccc(F)c2)nc1 +CCn1ccc(C(=O)Nc2nnc(-c3csc(C)n3)o2)n1 +O=C(CC(C1CC1)C1CC1)NCCc1ccc(O)cc1 +Cc1nc(C(=O)N2CCOC(C)C2)nn1-c1ccc(Cl)cc1 +COCCN1CCN(C(=O)NCCC(F)(F)F)CC1=O +N#CCCN(Cc1ccco1)C(=O)c1ccncc1 +O=C(NCC(F)(F)F)c1csc(-c2ncccn2)n1 +CCC(C)C(=O)NCC1(NC(=O)C(C)CC)CCOCC1 +O=C(Cn1c2c(sc1=O)CCCC2)N1CCCC2CCCCC21 +CCC1(C)CCCN(C(=O)c2cccc(OCC(F)F)n2)C1 +COC(C)(C)c1noc(-c2occc2Br)n1 +COc1ccccc1OC(=O)Cn1ncc(=O)c2ccccc21 +CCCCNC(=O)CN1CC(C)Oc2ccc(N)cc21 +CCN(Cc1cnc2ccccn12)C(=O)NCc1ccc(OC)cc1 +CCc1cc(C(=O)NCc2ccc(OC)c(OC)c2OC)[nH]n1 +Cc1ncc(CNC(=O)NC(C)c2cccc3ccccc23)s1 +C#CCNC(=O)CSc1nnnn1-c1cccc(C)c1 +COc1cc(C(=O)NCc2ccccn2)cc(Cl)c1OC +CC(C)n1c(CO)nc2cc(C(F)(F)F)ccc21 +O=C(NCCCC1CCCC1)N1CCC(CO)CC1 +COC(=O)c1cccc(Cn2nnc(-c3ccsc3)n2)c1 +Cc1ccc2c(c1F)C(C(=O)Cc1ccc(O)cc1)NCC2 +Nc1nc(SCc2nc(CCc3ccccc3)no2)n[nH]1 +COc1ccc(C(C#N)NC2CC2)cc1OC(F)F +COC(=O)c1ccc(NC(=O)c2cccnc2C)c(Br)c1 +O=C(Nc1ccc2nc(N3CCOCC3)sc2c1)c1ccc[nH]1 +CCN(Cc1ccccc1)C(=O)COc1ccc(OC)cc1 +CC(=O)Nc1cccc(-c2nccn2Cc2cccc(N)c2)c1 +CCCCNC(=O)Cn1cnc2ccsc2c1=O +Cc1cc2c(cc1N)c(-c1ccccc1)nc(=O)n2C(C)C +COc1cccc(C(C#N)NS(=O)(=O)c2cccs2)c1 +O=C(NCc1ccccn1)c1cn2ccsc2n1 +CCc1nc2ccccc2n1C(CC)C(=O)NCc1ccccn1 +COc1ccc(-c2c(C(F)(F)F)noc2N)cc1 +Cc1cc2c(cc1NC(=O)N(C)Cc1ccoc1C)OCO2 +O=C(Cn1cnc(C2CCC2)cc1=O)N1CCOCC1 +O=S(=O)(c1cccc(F)c1F)N1CCCC2(C1)OCCO2 +CCC(=O)Nc1cccc(C(=O)Nc2ccc(C)cc2C(=O)NC)c1 +Cc1c[nH]c(=O)n1-c1ccc(C(=O)NCC(O)c2ccccc2)cc1 +COc1cc(CNC(=O)NCCOc2cccc(Cl)c2)ccn1 +O=C1CCCCCN1CCCNc1ncc(Br)cn1 +N#Cc1cc(S(=O)(=O)NCc2cn3ccccc3n2)ccc1Cl +O=C1COc2cc(-c3c(N4CCOCC4)c(=O)c3=O)ccc2N1 +Cc1cccc(NC(=O)c2ccc(NC(=O)C3CC3)cc2)c1 +CC(CC(=O)c1ccco1)NC(=O)C1CCCc2ccccc21 +C#CC(CC)(CC)NC(=O)Nc1ccc2c(c1)OCO2 +COc1ccc(CNS(=O)(=O)c2ccc(F)cc2)cc1 +CN(C)C(=O)c1cc(C(F)(F)F)ncc1OC1CC1 +Cc1nc(C)c(C(C)NC(=O)NC2CCOC(C3CC3)C2)s1 +O=C(c1ccc(F)c(F)c1)N1CCC(c2ccsc2)CC1 +CCCc1cc(=O)[nH]c2cc(NC(=O)CC(C)C)ccc12 +CC(Oc1ccccc1C(N)=O)C(=O)Nc1cccc(N)c1 +COc1ccc(C(=O)Nc2nc3ccc(NC(C)=O)cc3o2)cc1 +COCCNC(=O)c1cn(-c2ccccc2)c2ncccc12 +Cc1c(N)c[nH]c(=O)c1C(=O)N(C)CCc1ccncc1 +Cc1nn(C)c(C)c1C1CCCN1c1ncnc2c1CCC2 +COc1ccc(CNC(=O)N2CCOCC2C2CC2)c(OC)c1 +CCCCCCNC(=O)CN1CCN(C(=O)N(C)C)CC1 +CCN(CC)C(=O)c1sc(NC(=O)CC#N)c(C(=O)OC)c1C +NC(=O)Cn1cc(NCc2ccc(Br)cc2F)cn1 +Cn1c(SCCn2nc3ccccn3c2=O)nnc1-c1ccco1 +Cn1c(=O)oc2cc(NC(=O)NCC(=O)N3CCCC3)ccc21 +CCc1cc(NC(=O)NCC(C)C(=O)OC)n(C)n1 +O=C(NCCOc1ncccc1Cl)c1ccnc(OC2CCC2)c1 +CCC(=O)N(c1nc(C)c(C(C)=O)s1)C1CC1 +Cc1ccc(F)c2c1CCNC2c1ccc2nn[nH]c2c1 +Cc1cnn(CC(=O)N2CCCC3CCCCC32)c1 +CCC(NC(=O)c1ccc2ccccc2n1)c1ccc(OC)cc1 +NC(=O)Nc1ccc(NC(=O)Cn2c(=O)cnc3ccccc32)cc1 +O=C(Nc1nccs1)C12CC3CC(CC(O)(C3)C1)C2 +Cc1noc(NC(=O)CCCc2nnc(-c3ccccc3)o2)n1 +O=C(COc1ccc(Cl)cc1)Nc1ccccc1-n1ccnc1 +Cc1cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)no1 +O=C(NCC1(COc2ccccc2)CC(O)C(O)C1)C1CCCC1 +Cc1cc(OCC(=O)NCc2ccncc2)ccc1Cl +Cc1ccc(-c2nc(C(=O)OCc3cncs3)cs2)o1 +CN(Cc1ccco1)S(=O)(=O)c1cccc(N)c1 +Cc1cc(C(=O)N(CCCO)Cc2ccc(Cl)c(Cl)c2)no1 +COCCN(C(=O)Cn1nnn(-c2cccs2)c1=O)C1CC1 +Cc1ncsc1COC(=O)C1COc2ccccc21 +Cc1cc(C(=O)OCCOc2ccccc2F)c(C)o1 +Cc1noc(C)c1CC(=O)N(CCc1ccccc1)Cc1ccncc1 +C=CCOc1ccccc1CN1CCn2c(nnc2C(F)(F)F)C1 +CC(C)CNC(=O)C1CC(=O)N(c2cnn(C(C)C)c2)C1 +C=CCn1c(C)nnc1SCC(=O)N(C)C1(C#N)CCCCC1 +CN(CC(=O)NC1CCCCC1)C(=O)c1c[nH]c2ccccc12 +COc1ccc(C(=O)c2ccc(OCCN3CCOCC3)cc2)cc1 +COc1ccc(C2CCCN2C(=O)Cn2cc(Cl)cn2)cc1 +Cc1cccc(C)c1OCCCN1CCn2c(nn(C)c2=O)C1 +COC(=O)CNC(=O)c1csc(Cc2ccc(C)cc2)n1 +O=C(Nc1ccc(OCC2CCCO2)cc1)C1CCCc2[nH]ncc21 +C#CCN(Cc1ccc(F)cc1)C(=O)c1ccsc1 +Brc1ccc(-n2nccc2-c2cccnc2)cc1 +CCn1c(=O)c2c(nc3n(-c4ccccc4C)c(C)cn23)n(C)c1=O +O=S(=O)(NC1CCC(O)CC1)c1ccccc1C(F)(F)F +COc1ccc(OC)c(CN(CCO)C(=O)c2ccc(C)nc2)c1 +C#CCCNC(=O)c1ccc(OC(F)(F)F)cc1 +CSc1ccc(C(=O)Nc2nnc(Cc3cccs3)o2)cc1 +Cc1cnn(CC2CCCN2C(=O)c2cccc(-n3ccc(C)n3)c2)c1 +CCN(CC1CC1)C(=O)Nc1ccc(Cl)c(NC(C)=O)c1 +C=CCNC(=O)NC1CCOc2c(Cl)cccc21 +Clc1cccc(-c2cc(-c3nc(-c4ccncc4)no3)n[nH]2)c1 +Cc1cc(N2CCN(C(=O)c3ccsc3)CC2)n2ncnc2n1 +CC(CNC(=O)c1scnc1C1CC1)Oc1ccc(F)cc1 +CC(NC(=O)Nc1ccc(F)c(Cl)c1)c1ccccn1 +COCCOc1cccc(NC(=O)N(C)CC(C)C)c1 +Cc1ccccc1NS(=O)(=O)c1ccc2c(c1)C(C)(C)C(=O)N2 +CCCCOc1cccc(C(=O)N2CCNC(=O)C2(C)C)c1 +O=C(N1CCCCCC1)C1(c2cc(-c3ccco3)on2)CC1 +COc1ccc(Cl)cc1NC(=O)c1cc(S(N)(=O)=O)oc1C +CC(=O)N(C)c1nc(C2NC(=O)c3cc(Cl)ccc3N2)cs1 +COCC1CCCN1C(=O)c1cnc(N)nc1-c1ccccc1 +COCC(C)N1CCN(c2nn3cc(C(C)(C)C)nc3s2)CC1 +Cc1cc(C(=O)N(Cc2ccccc2)CC2(O)CCCC2)[nH]n1 +NC(=O)c1ccc(CNCCc2ccccc2F)cc1 +COc1ccc(CC(=O)OCC(=O)N2CCCCCC2)cc1 +CS(=O)(=O)c1ccccc1SC1C=CCCC1 +CCOc1ccccc1OCC(=O)NC(C)(C)c1nc(C)c(C)s1 +COc1ccc(CCC(=O)N2CCc3ccc(OC)cc3C2)cc1 +CC(NC(N)=O)C(=O)Nc1ccccc1OCC(F)(F)F +Cc1ccc(C(C)Nc2ccc(N)cc2F)s1 +Cc1cc(C)n(-c2cccc(CN(C)C(=O)CN3CCNC3=O)c2)n1 +CC1(C(=O)N=c2[nH]c3ccccc3[nH]2)Sc2ccccc2NC1=O +CC(C)(C)C(O)CN1CCN(C(=O)C2CCC(C(N)=O)CC2)CC1 +COC(=O)CN(C)C(=O)c1ccc(NC(=O)OC(C)(C)C)cc1 +CCCc1nnc2sc(NC(=O)c3cc(OC)cc(OC)c3)nn12 +O=C(NC1CCCCC1)c1cnc2sccn2c1=O +Cn1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1=O +CCC(CCO)NC(=O)NC1CCCC1Cc1ccccc1 +C=CCn1c2cc(C)sc2c2cnn(CCC)c(=O)c21 +O=C1CCc2ccccc2N1CCC(=O)N1CCOCC1C1CC1 +Cc1noc(CCNC(=O)CCn2ccc3ccccc32)n1 +CCCn1c(SCc2nc(C)c(C)o2)n[nH]c1=O +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccc3c(c2)CCC3)c1C +N#Cc1ccc(OC(=O)c2ccn(-c3ccccc3)n2)cc1 +CC(=O)NC(CC(=O)NCc1nc(C2CC2)no1)c1cccs1 +COc1cc(CNc2cc(C)n(C)n2)cc(OC)c1OC +COc1ccccc1OCCSc1nc(C)cs1 +Cc1ccsc1-c1nc(-c2cccc(N)c2)no1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)Cn1ccccc1=O +CC1(C)C(Cc2cc(CO)on2)CC1NC(=O)C1CCCCC1 +Cc1c(C(=O)NCC2CCC2)nnn1-c1cccc2cnccc12 +CC(C)CC(=O)Nc1ccc2[nH]c(CCC(C)O)nc2c1 +NS(=O)(=O)c1ccc(NC(=O)CCc2ccsc2)cc1 +Cc1ccc(Cl)cc1N1CCN(CCC#N)CC1 +Cc1cccn(CC(C)(C)C(=O)Nc2cccc(C#N)c2)c1=O +COCCN(CC(C)C)C(=O)c1cc2ccccc2n1C +CC(C)Oc1ccccc1CCC(=O)N1CCn2c(cccc2=O)C1 +CCOC1CCN(Cc2ccncc2)C1Cc1ccncc1 +CCOCCNC(=O)N1CCN(C(=O)c2ccco2)CC1 +O=S(=O)(Cc1ccc(Cl)cc1)N1CCc2ccccc2C1 +Cc1cccc(CCC(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)c1 +Fc1ccc(-c2csc(C3COCCN3)n2)c(F)c1 +NC(=O)c1c2c(nc3ccccc13)C(=Cc1ccco1)CCC2 +CC(C)C(=O)Nc1ccc(NC(=O)N(C)C(C)c2ccccn2)cc1 +CSc1ncccc1C(=O)NCC1(c2ccc(F)cc2)CC1 +Cc1cc2nc(N)nn2cc1-c1cccc(N(C)C)c1 +Cc1ccc(CN(C)C(=O)Cc2csc(-c3cnccn3)n2)s1 +COc1ccc(C)cc1CN(C)S(=O)(=O)CCCO +CCC(=O)Nc1ccc(Nc2nnc(C)c(C)c2C#N)cc1C +O=C(Nc1cccc(N2CCCCC2)c1)NC1CCCc2occc21 +C#CCOc1cc(F)ccc1NC(=O)NCc1ncc(C)s1 +C#CCN1CCN(C(=O)NCCNC(=O)c2ccc(Cl)cc2)CC1 +CC(NC(=O)c1ccco1)C(=O)OCc1cccc(C#N)c1 +Cn1nc2c(cc1=O)CN(c1cccc(F)c1C#N)CC2 +Cc1n[nH]c(C)c1NC(=O)CCc1ncc(-c2ccccc2Cl)o1 +Cn1cnc(S(=O)(=O)NCC(=O)NCc2cc(F)ccc2F)c1 +Cc1noc(CNC(=O)CCC(=O)c2ccc(Cl)cc2)n1 +CCc1cccc(NC(=O)Cn2ccc3c(=O)n(C)c(=O)n(C)c32)c1 +COC(=O)c1cc(S(=O)(=O)NCCC2=CCCCC2)c[nH]1 +C=CCn1c(SCCOCC)nc2ccccc2c1=O +CC(=O)N1CCC(C(=O)NCC#Cc2ccc(C(N)=O)cc2)CC1 +C=CCN1C(=O)CCCC12CCCN(C(=O)c1ccnnc1)C2 +CN(Cc1ccc(C#N)cc1)C(=O)c1cccnc1 +Cc1ccccc1NC(=O)c1cc2cccn2cn1 +CC(C)(C)c1nc(CSc2nnc(NC3CC3)s2)no1 +CN(C(=O)c1ccc(-n2cnnn2)cc1)C1CCCc2ccccc21 +CCOc1ccc(CC(=O)N2CCC(c3ccsc3)CC2)cc1 +CCCN(C)C(=O)c1cc(COc2ccc(Cl)cc2OC)on1 +OC1COc2cc(OCc3cccc(F)c3)ccc21 +COCC(C)NC(=O)NCC(=O)Nc1ccc(F)c(F)c1F +O=C(NCCCn1cccn1)Nc1ccc(Cl)c(F)c1 +CC(C)(C)C(=O)NC(c1ccccc1)c1nnc(N2CCOCC2)o1 +Cc1cc(C)n(CCCC(=O)NC(C)c2ccc3c(c2)CCC3)n1 +COC1CCN(C(=O)Cn2cnc3ccccc32)CC1 +CCCCNC(=O)c1cc2c(=O)n(C)c3ccccc3c2n1C +Cn1cc(S(=O)(=O)NCCN2CCN(c3ccccc3)CC2)cn1 +Cc1ccc2cc(C(=O)N(CCC(N)=O)Cc3ccccc3)[nH]c2c1 +CN(C1(C#N)CCC1)S(=O)(=O)c1cnn(C)c1 +O=C(Cn1c(=O)oc2cc(Cl)ccc21)NCc1ccco1 +Cc1nc(COc2ccc(C(=O)N3CCc4ccccc43)cc2)no1 +Cc1ccc(NCC(=O)Nc2ccc(Cl)cn2)cc1F +Cc1cccc(NC(=O)CNC(=O)NC2CCCCC2)n1 +CC1CCN(S(=O)(=O)c2ccc3c(c2)OC(C)(C)C(=O)N3)CC1 +O=C(COc1ccc(-c2nc3ccccc3[nH]2)cc1)N1CCOCC1 +CCCCCSc1nnc(-c2cccnc2)n1N +CCC(=O)Nc1cccc(S(=O)(=O)N2CCCCCC2)c1 +CCn1c(-c2cc(C)ccc2C)ccc(C#N)c1=O +CC(C)C(NC(=O)NCC1CCOC1)c1cccs1 +O=S(=O)(Nc1cn[nH]c1)c1ccc(F)c(C(F)(F)F)c1 +COc1ccc(SC(C)C(=O)OCC2CCCO2)cc1 +Cc1nnc(NC(=O)CN2CCOC(Cn3cccn3)C2)s1 +CN(C)c1cccc(C(=O)NCCc2ccsc2)c1 +CC(C)OC(=O)C(C)(C(F)(F)F)C(F)(F)F +CCSc1ccc(NC(=O)c2ccc(OC)nc2)cn1 +CCCNc1nc(-c2sc(C(C)C)nc2C)cs1 +O=C(Nc1cnc(-c2ccccc2)nc1)c1ccc[nH]1 +Cc1nc2ccc(N)cn2c1C(=O)N(C)c1ccccc1 +Cn1nccc1-c1nnc(NC(=O)CCSc2ccc(F)cc2)o1 +Cn1cccc1-c1nnc(-c2cnc3onc(C4CC4)c3c2)o1 +CCCCN(CC(N)=O)C(=O)c1ccc(C(N)=O)nc1 +O=C(Nc1nc2c(ccc3ccccc32)s1)c1cccnc1 +C#CCCOc1ccc(CNc2ccc3c(c2)COC3)cc1 +Cc1cc(NC(=O)c2cnn3c(-c4ccccc4)ccnc23)ccn1 +CC1CNC(=O)CCN1Cc1cc(=O)c2cccc(F)c2[nH]1 +CCc1noc2ncc(S(=O)(=O)NCC(C)Cn3cccn3)cc12 +Cc1ccc(CNC(=O)c2cc3c([nH]c2=O)CC(C)(C)CC3=O)o1 +CC(C)Cc1noc(CN2CCOc3ccc(F)cc32)n1 +O=C(NC1CCCCCC1)c1nc(-c2ccncc2)no1 +CCN(CC)C(=O)CNC(=O)c1ccc[nH]c1=O +COCCNC(=O)c1ccc(=O)n(Cc2cccc(F)c2)n1 +c1ccc(-c2nc(NC3CC3)cc(-c3cccnc3)n2)cc1 +COc1cc(CNS(=O)(=O)c2ccc(OC)c(Cl)c2)ccn1 +Cc1cc(C)c(CNC(=O)CCc2cc(F)ccc2F)c(=O)[nH]1 +Cc1cc(N)c2onc(CC(=O)Nc3nc(C)cs3)c2c1 +Cc1nc(CC(=O)N(C)Cc2nc(-c3ccccn3)no2)cs1 +CC(C)CC(=O)N1CCC(NC(=O)Nc2ccc(F)cc2)CC1 +CCN(CC(C)C)C(=O)COc1ccc(C#N)cc1 +Fc1ccccc1C1CN(Cc2cc[nH]n2)CCO1 +CCc1ccc(OCC(=O)N2CCNC(=O)C2)cc1 +Cc1ccnc(SCc2nc3ccccc3s2)n1 +CCOC(C)c1noc(CN2CCN(c3cccc(F)n3)CC2)n1 +COC(=O)CCCn1c(C)nc2ccc(F)c(F)c21 +CC(NC(=O)CNC(=O)c1ccoc1)c1ccccc1 +CN(CC(=O)NC(C)(C)C)Cc1nc2sc3c(c2c(=O)[nH]1)CCC3 +CCOc1cc(C)c(S(=O)(=O)N(C)CCO)cc1C +CC(Nc1cccc(F)c1)c1ccc(S(C)(=O)=O)cc1 +CNC(=O)C1(C)CCCN(C(=O)Cc2ccccc2)C1 +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)c1ccncc1 +CCS(=O)(=O)NCc1ccc(C(=O)OC)cc1 +CS(=O)(=O)N(CC(=O)Nc1nccs1)c1cccc(Cl)c1 +O=C(Nc1ccccc1)N1CCN(Cc2nc3ccccc3o2)CC1 +O=C(Nc1cnc(-c2ccccc2)o1)c1ccccc1 +CC(C)N(CC(F)(F)F)C(=O)c1ccc(N2CCCC2)nn1 +Cn1cc(-c2nc(C(=O)NC(C)(C)C#N)cs2)cn1 +COc1ccccc1OC(C)CC(=O)N1CCNCC1 +Cn1c(N)c(NC2CCCCC2O)c(=O)[nH]c1=O +CC(C#N)CN(C)C(=O)c1cc2c(s1)CCCC2 +COc1ccc(C2CCCN2C(=O)CCc2nc(C(C)C)no2)cc1 +COc1ccccc1NC(=O)c1ccc(C)c(NS(C)(=O)=O)c1 +COCC(=O)Nc1ccc(OC(=O)Cc2ccc(F)c(F)c2)cc1 +CCn1nccc1C(=O)N1CCN(Cc2cc(C)cc(C)c2)C(=O)C1 +O=C(CSc1nncs1)NCc1ccco1 +Cc1c(Br)c(C(=O)NC(C)C(C)(C)C)nn1C +Cc1nc(NCc2cc(CC(C)C)no2)c2cccnc2n1 +N#Cc1cccc(S(=O)(=O)NCCCc2ccccc2)c1 +Cc1n[nH]cc1CNS(=O)(=O)c1cccc(Cl)c1 +COC(=O)C1(N(C)C(=O)c2cc(C)nc3c2cnn3C)CCCCC1 +CCC(C)NC(=O)CSc1nnc(-c2ccco2)n1CC +O=C(Nc1ccccc1NCC(F)(F)F)C1CCOC1 +O=S(=O)(Nc1ccccc1CO)c1ccccc1F +Nc1cc(C(=O)NCc2cn[nH]c2)ccc1Cl +CC(C)Nc1ncnc(Nc2ccc(F)cc2)c1N +COC(=O)CSc1cc(NC(C)=O)ccc1O +O=C(COCC1CCCCO1)N1CCC(CCn2cccn2)CC1 +CNC(=O)c1ccc(OCC(=O)NCCOC)c(N)c1 +Cc1cc2c(N)cccc2c(C(=O)NCCCN2CCOCC2)n1 +CN(CC(=O)N1CCN(c2ncccn2)CC1)C(=O)c1cccs1 +CCn1ncc2c1CN(Cc1ccc3c(c1)OCO3)CC2COC +CNC(=O)C1CC2CN(S(=O)(=O)c3ccc(C)cc3)CC1O2 +O=C(Nc1cccc(F)c1)c1coc(NC(=O)c2cccs2)n1 +Nn1c(SCC(=O)Nc2ccccn2)nnc1C(F)(F)F +Cc1cccc(-c2noc(C(C)NC(=O)c3cccnc3)n2)c1 +O=C(C1CCCCC1C(=O)N1CCc2ccccc21)N1CCCC1 +Cc1csc(=O)n1CC(=O)NCC(C)(C)c1ccncc1 +Cc1csc(NC(=O)C2CC(=O)N(C(C)c3ccccc3)C2)n1 +COC(=O)c1cc(Cl)c(NC(=O)N(C)C)cc1OC +Cc1ccc(NC(=O)CSc2nnc(N)n2C)cc1 +O=C(c1ccc2ncn(-c3ccccc3)c2c1)C1CC1 +COC(=O)CNC(=O)c1ccccc1-n1cnnn1 +O=C(NC1CCSc2c(F)cccc21)C1CCCCC1 +C=CCN(Cc1ccccc1)S(=O)(=O)CCC +CCn1c(=O)[nH]c2cc(C(=O)OCC#Cc3ccccc3)ccc2c1=O +COc1ccc2[nH]c(C(=O)NCc3cccs3)cc2c1 +CCC(=O)Nc1cc(Cl)c(Cl)cc1NC(=O)CC +Cc1ccc(OCCc2nc(C)c(C#N)s2)c(C)c1 +COCc1ccc(C(=O)NC(c2ccccc2)C(C)C)o1 +CCC1(O)CCN(C(=O)Cc2csc(C(C)=O)c2)CC1O +CC1(C)CCN1C(=O)C1CCCN1c1ncnc2sccc12 +COc1ccc(CNC(=O)Cn2ccnc2)cc1OC +N#Cc1ccccc1CNc1cnc2ccccn2c1=O +COc1ccc(-c2onc(C)c2C(=O)NCC2CCCO2)cc1 +COc1ccc(NC(=O)NCc2ccc3c(c2)OCO3)cc1 +CCCC1(CO)CCCN(C(=O)c2ccc(OC)c(F)c2F)C1 +CCN(CC)c1ccc(C(=O)Nc2cc(C)n[nH]2)cc1 +COc1ccc(OCCc2nc(-c3ccc(C#N)cn3)no2)cc1 +COC(=O)CCC(=O)NCC(=O)Nc1ccc(Cl)cc1 +COc1ccc(NC(=O)CN(C)c2ccc(F)cc2)cc1OC +CC(C)C(=O)c1ccc(OCCN2CCOCC2)cc1 +COCCNC(=O)Nc1ccc(OCc2ccco2)c(Cl)c1 +CC(C)C(=O)N1CCC(C(=O)N(CCC#N)CCC(F)(F)F)CC1 +COc1ccc(CCOc2ccc(N)cn2)cc1OC +Cc1csc(=O)n1Cc1cccc(NC(=O)OC(C)(C)C)c1 +COC(=O)CSc1nc(COc2ccc(Cl)cc2)n[nH]1 +CN(CCc1ccc(F)cc1)C(=O)Nc1cccnc1-n1cncn1 +CCc1cc(C(=O)N2CCN(CCO)CC2)sc1C +Cc1ncsc1CCN(C)C(=O)C1CC(=O)N(C2CCCC2)C1 +COc1c(C)cc(-c2cc(=O)[nH]c(N)n2)c(C)c1C +COCCOCC(=O)N1CCC(c2ccc(F)c(F)c2)CC1 +CN(Cc1ccc(Oc2cnccn2)cc1)Cc1nccs1 +CN(CC1CCCO1)C(=O)c1cccnc1OCC(F)F +O=C(CN1CCc2ccccc21)Nc1cc(C(F)(F)F)c[nH]c1=O +O=C(c1ccncc1Cl)N(Cc1ccccn1)CC1CCCO1 +CC(C)OC(=O)CNC1=NS(=O)(=O)c2ccccc21 +CC(C)(C)OC(=O)N1CCC(CCOCc2cnccn2)CC1 +C=CCSc1ccccc1NC(=O)c1cnn(C)c1 +Nc1[nH]nc(-c2ccc(Cl)cc2)c1Br +Cn1nccc1CNC(=O)N1CCCC(C(=O)NCC2CC2)C1 +CC(NC(=O)c1c(F)cccc1Cl)c1ccc(-n2ccnc2)cc1 +CCCCCOc1ccccc1-c1cc(C(N)=O)nc(N)n1 +COC1CCCN(Cc2cnc(N3CCOCC3)nc2)C1 +CCOc1ncccc1NC(=O)C1CCN(S(C)(=O)=O)CC1 +COc1ccc(-c2cc(N)ncn2)c(-n2cccn2)c1 +Cc1[nH]c2c(c1C(=O)N1CCCC3(CN(C)C(=O)O3)C1)C(=O)CCC2 +CC(CNC(=O)NCc1cccnc1)N(C)c1ccccc1 +CC(C)C(=O)c1ccccc1NC(=O)Cn1nc2ccccn2c1=O +CC(CO)NC(=O)c1ccc(CCC(C)(C)O)cc1 +O=c1[nH]c(NCC(O)COc2ccccc2)nc2ccccc12 +CN(C(=O)c1cc(-c2ccc(F)cc2)[nH]n1)C1CC1 +Cc1c(C(=O)OCC2CCC(=O)N2)oc2c(Cl)cccc12 +CN(CC1CC(=O)N(C2CCCC2)C1)c1nnc(C2CCC2)o1 +CC(C)Oc1ccc2c(C(=O)NCc3cccnc3)cc(=O)oc2c1 +CC(NC(=O)OCc1ccccc1)C(=O)N1CCCC1 +CCOC(=O)Nc1cccc(-n2ccnc2-c2ccsc2)c1 +COC(CNC(=O)c1ccccc1F)c1ccsc1 +CSc1nnc(CNC(=O)Cn2cccn2)n1Cc1ccccc1 +CCc1cccc(C)c1NC(=O)c1cccc(F)c1 +CCCN(CCC)C(=O)c1ccccc1OC(C)=O +Cc1csc(NC(=O)C2CCN(c3cccc(F)n3)CC2)n1 +COC(=O)NC(C)(C)C(=O)NCCc1ccccc1Br +Cc1nn(-c2ccc(F)cc2)c2sc(C(=O)N(C)CCC#N)cc12 +CCCC(=O)N1CCCC(C(=O)OCC(=O)NC)C1 +CN(C)C(=O)c1cccc(-c2ccc(O)c(Cl)c2)c1 +COc1cc(C(=O)N2CCC2)ccc1OCc1ccccc1 +O=C(C1CNCCN1C(=O)CCCc1ccccc1)N1CCCC1 +Cc1cc(C)c2c(c1)c(C)cc(=O)n2CC(=O)NCc1ccco1 +Cc1cc(Cl)ccc1OS(=O)(=O)c1cc(C(N)=O)n(C)c1 +Cc1cc(N)nc(SCC(=O)NCc2cc(F)cc(F)c2)n1 +Cc1cccc(OC2CCN(C(=O)c3ccncc3)CC2)c1 +Cc1cc(NC(=O)c2ccc(-n3cccn3)cc2)no1 +CC(=O)c1c(C)[nH]c(C(=O)NC(c2ccccc2)C2CC2)c1C +CCN(CC)S(=O)(=O)c1ccc(NC(=O)CC2CCCC2)cc1 +NS(=O)(=O)N1CCN(C(=O)c2cc(Cl)c[nH]2)CC1 +COc1cccc(C(=O)NCc2ccc(NC(=O)C3CC3)cc2)c1 +CCOC(=O)CNC(=O)Cc1ccc(Cl)c(Cl)c1 +N#CCc1nc2cccc(F)c2n1Cc1cccc(C#N)c1 +CCOC(=O)C1(NC(=O)CSc2ccccc2F)CCCC1 +CCOc1cccc(NC(=O)c2cnc(C3CCCO3)s2)c1 +COc1ccc(C(=O)CCNc2c(C)cccc2C)cc1 +CC(Nc1cccc(CO)c1)c1cc(F)ccc1F +N#Cc1ccc(S(=O)(=O)NCCc2cccc(Cl)c2)cc1 +CN(Cc1ccco1)C(=O)c1cc(OCC(=O)N2CCCC2)n(C)n1 +CCC(C)(C)NC(=O)c1cnc2c(c1)c(=O)[nH]c(=O)n2C1CC1 +COc1ccc(CCNC(=O)Nc2ccc3oc(=O)ccc3c2)cc1 +COc1ccc(CN(C(=O)C2CCCO2)C2CC2)cc1 +C#CCN1CCN(C(=O)NCc2ccc(OC)c(C)c2)CC1 +Cc1nc(N(C)C)sc1CN1CCC(OCC(C)C)CC1 +CC(CC(=O)OCC1CCCO1)c1ccc(F)cc1 +COCCN1CCN(C(=O)NC(C)Cc2ccccc2C)CC1=O +CC(C)(C)c1cn(-c2ccc3c(c2)CNCC3)cn1 +COc1ccc(NC(C)=O)cc1NC(=O)c1scnc1C1CC1 +O=C(Nc1ccc2[nH]c(C3CCCO3)nc2c1)C1CCC1 +C=CCNC(=O)c1ccccc1NC(=O)Cc1ccc(F)cc1F +Cc1cc(C)c(CNC(=O)NCCc2c(C)nn(C)c2C)c(=O)[nH]1 +COC(=O)C1CCc2nc(Cc3ccccc3SC)nn2C1 +COCCC(=O)CCCc1c(F)cccc1Cl +CCN1CCN(Cc2cccnc2NC)C(=O)C1=O +O=C(OCC1CCCCC1)C1CC(=O)N(CC2CC2)C1 +N#Cc1cnn(-c2ccc(C(F)(F)F)cn2)c1N +Cc1cc(C)c(NC(=O)CN(C)S(=O)(=O)c2cccnc2)c(C)n1 +CCOc1ccc(NC(=O)c2nnn(-c3ccc(F)cc3)c2C)cc1 +CC(=O)Nc1cccc(C(=O)NC(c2ccc(F)cc2)C(C)C)c1 +CCn1cnnc1CNC(=O)Nc1ccc2c(c1)OC(C)(C)O2 +Nc1ccc(F)cc1C(=O)NCC1Cc2ccccc2O1 +O=C(Nc1cnn(CC(F)F)c1)N1CCOCC1C1CC1 +Cc1nc(C)c(CC(=O)NCCCOc2c(C)cccc2C)c(=O)[nH]1 +Cc1noc(NC(=O)c2cnn(-c3ccncc3)c2C)n1 +O=C(NCCOc1cccc2cccnc12)c1ccc(=O)[nH]c1 +CCC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc1cc(C)on1 +Cc1ccc(C(O)CNc2ccc(C#N)cc2)cc1 +COc1ccc(C(=O)N2CCOCC2)cc1NC(=O)CCC(C)(C)C +CC(=O)NC(C(=O)Nc1nc(-c2ccccn2)cs1)C(C)C +CCOC(=O)c1nn(Cc2ccc(C#N)cc2)c(N)c1C +COC(=O)Cn1cc(NC(=O)c2c[nH]c(=O)cn2)cn1 +O=C(Nc1ccccc1)C1CCCN1C(=O)Nc1ccccc1F +CCc1cc(C(=O)OC2CCCCC2OC)n[nH]1 +Cc1ccc(-c2csc(NC(=O)c3snnc3C)n2)cc1C +CC(C)C(=O)N1CCC(NC(=O)c2cc3c(F)cccc3s2)CC1 +CC(OCC(F)(F)F)C(=O)Nc1ccccc1-n1cnnn1 +CC1CN(C(=O)Cc2ccccc2Cl)CC(C)O1 +CC(=O)c1ccc(NC(=O)NCCOCC(C)C)cc1C +COc1cc(CNC(=O)Cc2ccccc2OC)ccn1 +COCCNC(=O)Nc1nnc(Cc2cccc(OC)c2)s1 +Cn1cc(NC(=O)Nc2cnn(CC(N)=O)c2)cn1 +COCCNC(=O)c1cccc(NC(=O)c2ccc(C(C)C)cc2)c1 +CC1CN(C(=O)c2ccc(NC(=O)c3cccn3C)cc2)CC(C)O1 +N#Cc1c(COc2cccc(C(N)=O)c2)cn2ccccc12 +Cc1coc(-c2cccc(NC(=O)NCc3nc(C)sc3C)c2)n1 +O=C(NCc1cccs1)c1ccc(-c2csc(C3CC3)n2)cc1 +CSc1ccc(CN(C)C(=O)COc2ccccc2)cc1 +Cn1c(=O)n(C)c2cc(CCCn3cc(N)cn3)ccc21 +Cc1nn(C)c(C)c1C1CCCN1C(=O)CCNS(C)(=O)=O +O=C(Nc1ccc(Cl)cc1F)C1CCN(C(=O)C2CC2)CC1 +CN(C)C(C(=O)N1CCNCC1)c1ccccc1Cl +O=C(Nc1cc(-n2cccc2)ccc1F)c1ccc(-n2ccnn2)cc1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)N1CC(C)CC(C)C1 +CC(C)(C)c1noc(-c2ccc(=O)n(Cc3cccc(C#N)c3)n2)n1 +O=C(CS(=O)(=O)c1ccc(O)cc1)Nc1cccc(F)c1 +CC(=O)Nc1cccc(C(=O)Nc2nc3ccc(Cl)cc3s2)c1 +O=C(NCc1ccco1)C1COCC2CN(c3ccncn3)CC21 +CS(=O)(=O)N1CCOCC2(CCC(Cn3cccn3)O2)C1 +COC(=O)c1ccc(NC2(C#N)C(=O)Nc3ccccc32)cc1 +COc1ccc(C(C)=O)cc1CC(=O)Nc1cc(F)ccc1OC +COC(=O)C(C)(N)c1ccc(OC)c(C(C)(C)C)c1 +C=CCN1CCN(Cc2cccs2)Cc2cccnc21 +O=C(NCc1nncn1-c1ccccc1)c1cc2c(cc1O)CCCC2 +Cn1cc(C(N)=O)cc1C(=O)Nc1ccccc1OCC(F)(F)F +COc1ccc2ccc(OCC(=O)N3CCCC3)cc2c1 +COC(=O)c1cc(C)ccc1NCc1c(C)noc1C +c1cc(CN2CCCC(c3nccs3)C2)cc(-c2ccncc2)c1 +NC(=O)CCSc1nc(-c2ccco2)nc2ccccc12 +COc1cccc2c1OCC(C(=O)NCCN(C)c1ccccc1)C2 +CC(c1ccc(S(N)(=O)=O)cc1)N(C)C(=O)c1ccccc1 +Cn1cc(C(=O)NC(c2c(F)cccc2F)C(F)(F)F)ccc1=O +Cc1noc(C)c1CC(=O)NCc1nc2ccccc2[nH]1 +CC(=O)c1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1C +COc1ccc(CCN(C)C(=O)c2ccccc2N)cc1OC +Cc1c(C(=O)OCCNc2ncccn2)cnn1-c1ccccc1F +O=C(Cn1cnnn1)N1CCN(C(=O)c2cc(F)cc(F)c2)CC1 +Cc1ccccc1OCC(=O)NCCc1cnn(-c2ccccc2)c1 +O=C1COc2cc(C(=O)Nc3ccccc3Cl)ccc2N1 +C=CCOc1ccc(C(=O)Nc2ccccc2-n2cnnn2)cc1 +COc1ccc(C2CCCN2C(=O)Nc2cc(C)on2)cc1OC +COC(=O)c1cc(COc2ccc(C(C)=O)cc2OC)oc1C +CS(=O)(=O)N1CCC(Cc2ccc(-n3ccnc3)nc2)CC1 +CCC(=O)Nc1cccc(NC(=O)N(C)Cc2ccccc2)c1 +CC(C)CC(=O)N1CCN(C(=O)c2ccc(O)cc2)CC1 +COc1ccccc1-n1nnnc1SCC(=O)Nc1ncccn1 +N#Cc1cccnc1N1CCCN(C(=O)C2CC2)CC1 +CNS(=O)(=O)c1ccc(C)c(NC(=O)c2ccc(C)c(F)c2)c1 +COC(=O)c1c(NC(=O)c2ccc(F)cc2F)sc(C)c1C +CC(C)n1c(SCC(=O)NCc2cccnc2)nnc1N(C)C +Cc1cc(C)n(-c2ccc(NCC(O)CN3CCOCC3)nc2)n1 +CCc1nnc(NC(=O)CSc2cc(C)[nH]c(=O)n2)s1 +CC(=O)c1cccc(NC(=O)c2cnc3[nH]nc(C)c3c2)c1 +COc1cc(CN2CCn3c(nnc3C(F)(F)F)C2)cc(OC)c1 +CC(=O)N1CCN(C(=O)Cc2ccccc2)CC1C(N)=O +CC(C)Oc1ccc(S(=O)(=O)N(C)C(C)(C)C#N)cc1 +CCC(CC)N(CCO)S(=O)(=O)C1CCOCC1 +C#CCOC(=O)c1sc(NC(=O)c2cccc(F)c2)cc1C +CCOc1cccc2c1C(C=Cc1ccco1)NCC2 +O=C(c1ccccc1)N1CCN(C(=O)c2csnn2)CC1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)Nc3ccnc(C)c3)ccc21 +O=C(COc1ccccc1)NCC1COc2ccccc2O1 +Cn1cc(C#N)c(-c2ccc(Br)cc2)n1 +O=C(c1cc[nH]n1)N1CCN(Cc2nnc3n2CCCCC3)CC1 +CC(CC(=O)N1CCc2cnccc21)C(=O)c1cccc(F)c1 +C=CCc1c(C)nn(-c2nc(CC(=O)NC(C)C)cs2)c1C +Cc1ncsc1C(=O)NC(C)C(=O)NC1CCCC1 +c1ccc2c(N3CCOC(Cn4cccn4)C3)ncnc2c1 +Cc1c(NC(=O)NCc2cccnc2)cccc1OC1CCCC1 +CCCCN(CC(N)=O)S(=O)(=O)c1ccc(C)cc1C +CCN(Cc1ccccc1N)S(=O)(=O)N1CCCC1 +O=C(Cn1nc2n(c1=O)CCCCC2)OCCOc1ccccc1F +CCOC(=O)c1ccc(CNc2nncc(-c3ccc(C)o3)n2)o1 +N#Cc1cc(C#N)c(SCc2coc(-c3cccs3)n2)nc1N +COc1cncc(-n2ccnc2-c2ccccn2)c1 +CC(=O)N1CCN(CC(O)c2ccc(C(C)(C)C)cc2)CC1 +Cc1nn(C)c(C(=O)Nc2ccc(CC#N)cc2)c1Cl +CCc1cccc(CC)c1NC(=O)NCc1cccc(C(N)=O)c1 +CN1CCc2nc3c(Cl)cc(Cl)cc3c(CO)c2C1 +Cc1ccc(F)cc1NCC(=O)NC(C)C(=O)N1CCCCC1 +COCCOc1cccc(NC(=O)c2cc(Br)c[nH]2)c1 +C=CCn1c(SCC(=O)NC)nc2cc(Cl)ccc2c1=O +Cc1ccc(F)cc1S(=O)(=O)N1CCC(C(=O)N(C)C)CC1 +Cc1nc2ncnn2c2ccn(-c3ccccc3Cl)c(=O)c12 +Cc1cc(C)c(N2Cc3ccc(N)cc3C2=O)c(Cl)c1 +Cc1ccc(-c2csc3ncn(CC#N)c(=O)c23)cc1 +Cn1nnc2c(=O)n(Cc3cccc(Cl)c3)cnc21 +CCC(CC)NC(=O)C(C)N1CCN(C(=O)c2ccco2)CC1 +Cc1cccc(-c2[nH]ncc2C(=O)NC2CCCCC2)c1 +O=C(c1cccnc1OCC(F)F)N1CCN(c2cnccn2)CC1 +Cc1ccc(Cl)cc1N1CCN(Cc2ccccn2)CC1 +CC(NC(=O)NCCCO)c1cccc(NC(=O)c2ccccc2)c1 +CCNC(=O)CCC(=O)c1ccc(CC(C)C)cc1 +Cc1n[nH]cc1CNC(=O)Nc1cccc(C(F)F)c1 +O=C(COc1ccccc1)c1cccc(C2OCCCO2)c1 +CCN(Cc1cc(C)c(OC)c(C)c1)CC(C)C#N +CC(C)c1noc(COC(=O)c2sccc2-n2cccc2)n1 +CC(Oc1ccc(-c2cnc3ccccc3n2)cc1)C(=O)NC1CC1 +C=CCn1c(SCC(=O)c2ccc[nH]2)nnc1-c1ccccc1 +COC(=O)c1ccccc1NC(=O)c1nn(-c2ccccc2)nc1C +COc1ccc(-c2onc(C)c2C(=O)NCc2ccc(C)o2)cc1 +COC(=O)c1[nH]c(C)cc1NC(=O)c1scnc1C1CC1 +CCCN1C(=O)CCC2CN(C(=O)Cn3nc(C)ccc3=O)CCC21 +NC(=O)CC(NC(=O)Nc1nncs1)C1CC1 +CCOCCn1c(CNC(=O)c2ccncc2)nc2ccccc21 +COCc1cccc(C(=O)N(C)Cc2ccccc2)c1 +CC(=O)N1CN(S(=O)(=O)c2ccc(C)cc2)CC1C +CC(O)CN(C)C(=O)Cc1cccc(C(F)(F)F)c1 +CC(C)NC(=O)c1ccc(-c2ccc(F)cc2)[nH]c1=O +Cc1nc(-c2ccc(NC(=O)c3nccn4ccnc34)cc2)oc1C +CC(C)c1ccccc1OCC(=O)N1CCN(C)CC1 +Cc1nnsc1CN(C)C(=O)C1CCCCC1 +CCOc1ccccc1C(=O)NCC(=O)NCC(C)C +COC(=O)c1sc2nc3ccc(OC)cc3cc2c1N +CNC(=O)CC1CCc2cc(OC)c(OC)c(OC)c21 +COc1c(Cl)cc(C(=O)N(CCO)C(C)C)cc1Cl +CCC(CC)N(C)S(=O)(=O)c1ccc(F)c(S(C)(=O)=O)c1 +CC(=O)N1CCCc2cc(NC(=O)c3cccc(F)c3)ccc21 +Cc1noc(C)c1CCCNC(=O)Nc1cnc2c(c1)c(C)nn2C +CCC(=O)N1CCC(C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)C1 +O=C(NCc1ccccc1)N1CCN(Cc2ccsc2)CC1 +COC(=O)c1cccc(CNC(=O)Cn2c(C#N)nc3ccccc32)c1 +CCNC(=O)C(C)Sc1nnc(-c2ccncc2)n1C +COc1ccccc1NC(=O)Nc1ccc(F)c(F)c1 +COC(=O)c1cc(COc2cc(C(N)=O)ccc2C)c(C)s1 +COc1ccc(CNC(=O)NCc2ccccn2)cn1 +Fc1ccc2[nH]c3c(NCc4ccco4)ncnc3c2c1 +COC1CCC(N(C)C(=O)CCc2c(C)nn(CC(C)C)c2C)CC1 +CC(C)(C)CC(=O)NC(Cc1ccccc1)C(=O)N1CCCC1 +Cc1cc(C)nc(C(C#N)C(=O)c2ccc(C#N)cc2)n1 +O=C(NC1CC1)N1CCC(C(=O)N2CCCCCC2)CC1 +COC(=O)c1ccc(N(CC(C)C)S(C)(=O)=O)cc1 +CC(=O)Nc1cscc1S(=O)(=O)c1ccccc1 +COc1ccc(C)cc1C(=O)CCc1nc(C)cs1 +O=C(c1cnc2ccccc2n1)N1CCCC1c1ccccc1 +Cc1n[nH]c(C)c1CCNC(=O)C1CC(=O)N(C2CCCC2)C1 +O=S(=O)(NCC1COc2ccccc2O1)c1ccc(F)c(F)c1 +CCn1nc(C(=O)N2CCN(c3ccccc3)CC2)ccc1=O +Cc1nn(C)c(=O)c(C(=O)N2CCc3cc(F)ccc3C2)c1C +COCC(C)NC(=O)N1CCN(Cc2ccc3c(c2)OCCO3)CC1 +Cc1ccc(NC(=O)c2sccc2C(C)C)cc1S(C)(=O)=O +Cc1cc(C)n2nc(C(=O)NCC3CCCC(C)C3)nc2n1 +O=C(Nc1cnc2ccccn2c1=O)c1ccc2ccccc2c1 +CN(CC1CCCN(C(=O)OC(C)(C)C)C1)c1nccs1 +CCC1CCCN(C(=O)NCc2cccnc2OC)C1 +CCOc1ccc(OCC)c(S(=O)(=O)n2ccnc2)c1 +Cc1ccc(-c2n[nH]c3c2CN(C(=O)c2cccn2C)CC3)cc1 +O=C(Cc1cccs1)N1CCC(Nc2cccnn2)CC1 +CC(C#N)CN(C)CC(=O)Nc1nc2c(s1)CCC2 +O=C(CSc1nnc(-c2ccccc2F)o1)Nn1cn[nH]c1=O +CN(c1cccc(NC(=O)C(C)(C)C)c1)S(C)(=O)=O +C#CCNC(=O)C(CC(C)C)NC(=O)NCc1ccc(C)cc1 +CC(C)(C)n1ncc2c(=O)[nH]c(NCc3cccc4cccnc34)nc21 +O=C(Nc1ccc2c(c1)COC2)c1ccc(-c2nc(C3CC3)n[nH]2)cc1 +COc1ccc2c(-c3ccc(N)cc3)noc2c1OC +CCCCOC(=O)Cn1cnc2ccc(Cl)cc2c1=O +Cc1nn(C)c2cnn(CCCNC(=O)C3CCCC3)c12 +O=C(Nc1c(-c2ccccc2)n[nH]c1C1CC1)c1ccc2c(c1)OCO2 +COc1ccc(Cl)cc1C(=O)NC(C)(C)CO +FC(F)n1ccnc1CN1CCN(Cc2cncs2)CC1 +N#Cc1nncn1Cc1nc2sc3c(c2c(=O)[nH]1)CCCC3 +NC(=O)c1ccccc1NC(=O)COc1cc(Cl)ccc1Cl +Cc1cc(CC(C)NC(=O)c2cc(C)nc3c(C)cccc23)[nH]n1 +O=C(NC1CCCNC1=O)c1ccc(-c2ccco2)[nH]c1=O +COc1cc(-c2cc(-c3ccc(C)s3)nc(N)c2C#N)ccc1O +CC(=O)Nc1ccc(F)c(C(=O)N(C)CC2CC2)c1 +COc1cccc(NCC(=O)N(C)Cc2ccccc2)c1 +O=C(NC1CCCCC12OCCO2)c1cc(Cl)c2c(c1)OCO2 +O=S(=O)(c1ccc(Br)cc1)n1ccc2cccnc21 +COc1cc2c(cc1-c1nccn1-c1cncc(C)c1)OCCO2 +Cn1nc(C#N)c2c1CN(C(=O)c1ccsc1)CCC2 +O=C(Cn1ncc(=O)c2ccccc21)Oc1cccc(-n2cccn2)c1 +CCCNc1ccc(C(=O)N2CCC3(CCOCC3)CC2)cc1 +COC(=O)NCC(=O)Nc1cccc(-n2cnnn2)c1 +CSc1ccccc1CC(C)NC(c1ccccc1)c1nc[nH]n1 +O=C1CCc2cc(NC(=O)C3CCCO3)ccc2N1 +Cc1nnc(SC(C)C(=O)Nc2ccccc2)n1N +Cc1nc(C)c(C(=O)N(C)Cc2cccc(OC(F)(F)F)c2)o1 +Cc1ccc(-c2nc(-c3ccccn3)no2)c(C)c1 +Cc1ccc(-n2ccnc2SCC(=O)NCC(F)(F)F)cc1C +COc1ccc(CNc2ncnc3c2cnn3-c2cccc(C)c2)cc1 +Cn1nc(-c2ccccc2F)c(-c2nc3ccccc3n2C)c1N +CCCCNC(=O)NCc1ccc(C(=O)N(C)C)cc1 +Cc1oc(C)c(C(=O)NCC(Cc2ccc(F)cc2)C(N)=O)c1C +NC(=O)CN1C(=O)COc2cc(NCc3ccc(F)cc3)ccc21 +COc1cc(C)ccc1NC(=O)Nc1nc(C)c(C)o1 +CC(=O)NCC(=O)N1CCC(OCC2CC2)C1Cc1ccccc1 +CCOC1C2CCC1N(Cc1nc(C)cs1)CCO2 +N#Cc1ccccc1OCc1nc(Cc2ccccc2)no1 +Cc1nn(Cc2ccc(Cl)cc2N)c(C)c1Br +CC(C)(C)c1noc(CCC(=O)NCC2(c3ccccc3)CC2)n1 +CCOc1ccc(-c2cn3c(N)csc3n2)cc1Cl +CCOC(=O)c1coc(NC(=O)Nc2ccc(F)cc2)n1 +CC(C)OCCOc1c(Cl)cc(Cl)cc1CO +Cc1ccc(N2C(=O)CCC(C(N)=O)C2c2cccs2)cc1 +Cc1c[nH]nc1C1CCCN1C(=O)c1ccc(Cl)cc1 +O=C(NC(CO)Cc1ccccc1)c1nc(-c2ccncc2)no1 +CCCOc1cccc(C(=O)Nc2cnn(C(C)(C)C)c2)c1 +Cc1ccc(NC(=O)N(C)C(C)CC#N)cc1NC(=O)C(C)(C)C +COc1ncccc1C(=O)N(Cc1cccnc1)CC1CCCO1 +Cc1cc(-c2nnc(NC(=O)C3CCCC3)o2)c(C)o1 +Cc1cc(S(=O)(=O)NCC(C)(C)c2ccncc2)ccc1F +CN(Cc1cn[nH]c1-c1ccc(F)cc1)C(=O)c1cccc(N)c1 +Cc1cc(NC(=O)C(C)OC(=O)c2c(C)oc(C)c2C)no1 +O=C(c1c(F)cccc1F)N1CCN(CCc2ccncc2)CC1 +CCCOc1ccc(CNC(=O)Nc2cc(OC)ccc2F)cn1 +NC(=O)c1ccccc1NC(=O)CSc1nncs1 +O=C(c1cc(-c2ccccc2)[nH]n1)N1CC(n2ccnn2)C1 +O=C1NC2c3ccccc3CN2c2c1[nH]c(=O)[nH]c2=O +CN1C(=O)COc2cc(NCc3ccc(F)cc3)ccc21 +COCCNC(=O)NC1(c2nc(-c3cnccn3)no2)CCCCC1 +CNC(=O)NCC(=O)NC(c1ccc(Cl)cc1)C1CCCC1 +CC(=O)NC(C)(C)c1noc(C(=O)c2ccc(C(C)(C)C)cc2)n1 +CCc1nc2c(NC(=O)c3ccc(OC)cc3C)cccn2n1 +C=CCC1(CO)CCCN(C(=O)c2c[nH]c(C)cc2=O)C1 +CC(=O)Nc1ccc(S(=O)(=O)N(CC(C)C)CC(C)C)cc1 +CCc1ncc(C(=O)Nc2ccccc2Sc2nncn2C)s1 +Cc1cc(C(O)CNc2c(C)cccc2C)ccc1F +Cn1cc(CC(=O)N(CC2CCCO2)c2ccncc2)c2ccccc21 +COCCN(c1nc2ccccc2s1)S(=O)(=O)c1ccccc1 +NC(=O)c1ccc(C#CCNC(=O)c2cc3ccccc3o2)cc1 +Fc1cccc(OCCc2nc3c(s2)CCCN3)c1 +CCCn1c(=O)c2c(c(-c3ccccc3)cn2C)n2c(=O)[nH]nc12 +COCCNc1ncnc(Nc2cc(Cl)ccc2C)c1N +COc1ccccc1NC(=O)COC(=O)Cc1ccc(Cl)cc1 +CC(C)c1cc(C(=O)N2CCOCC(CO)C2)c(O)c(C(C)C)c1 +NC(=O)NCC(=O)Nc1ccc(OCc2ccccc2F)cc1 +Cc1cc(-c2nnc(CN3c4ccccc4OCC3C)o2)c(C)o1 +Cc1ccc2ncc(C(=O)NC3(c4ncon4)CCOCC3)n2c1 +CC(O)(CC(=O)NCC1COc2ccccc2O1)C(F)(F)F +Cc1ccc(OC2CCN(C(=O)C3CCCC3)CC2)cn1 +COCCN(Cc1nccs1)C(=O)c1cnoc1C +CN1CCOc2ccc(NC(=O)Nc3ccccc3F)cc2C1=O +Cc1cc(CN(C)C(=O)c2nc(C(C)C)ncc2Cl)no1 +C=CCN(Cc1ccccc1)C(=O)Nc1nnc(CC(C)C)s1 +CCOC(=O)CN(CC)C(=O)Cn1ccc(=O)[nH]c1=O +CCS(=O)(=O)N1CCCC(C(=O)N2CCN(C)CC2)C1 +N#Cc1cccc(NC(=O)CCC(=O)Nc2cccc(C#N)c2)c1 +CCOc1cn(C)c(C(=O)NCCc2ccc(F)cc2)cc1=O +Cc1cccc(CCC(=O)N2CCN(C3CCCC3O)CC2)c1 +CCN(CC(F)(F)F)C(=O)Nc1ccccc1F +Cc1cc(C)c(CNC(=O)c2sc3ccc(F)cc3c2C)c(=O)[nH]1 +Cc1ccc(-c2ccc(=O)n(CCCNC(=O)C3CC3)n2)cc1 +Cc1nc(NCc2ccccc2)c2c3c(sc2n1)CCC3 +c1ncc(-c2nc(C3CCOCC3)nn2C2CCCCC2)[nH]1 +CNC(=O)c1ccnc(N2CCC(Sc3ccccc3C)CC2)c1 +N#CCc1ccc(NC(=O)c2ccnc(OC3CCC3)c2)cc1 +Cc1occc1C(=O)N1CCN(CC=Cc2ccccc2)CC1 +COC(=O)CC1CCCCN1S(=O)(=O)c1ccc(C)cc1 +CCS(=O)(=O)c1noc(C(=O)Nc2ccccc2)c1N +Cc1ccc(OC2CCN(C(=O)Nc3ccc(Cl)cc3)CC2)cn1 +COc1ccccc1S(=O)(=O)Nc1ccc(=O)n(C)c1 +Cc1nnc(SCC(=O)OC2CCCC2)n1-c1ccccc1 +CCCC(=O)Nc1nnc(-c2cc(OC)ccc2OC)o1 +CN(Cc1cnn(C)c1)C(=O)NCC(=O)Nc1ccc(Cl)cc1 +CCn1nc(C)c(-c2cncn2CCCOc2cccc(C)c2)c1C +Cc1noc(C)c1CCC(=O)N1CCC2CCCCC2C1 +CC1(C)CN(C(=O)c2cc(=O)c3ccccc3o2)CC1(C)O +Cn1cnnc1SCc1cn(-c2ccccc2)nc1-c1ccccc1 +COc1ccc(C(O)C(=O)NCc2nn(C)c3ccc(C)cc23)cc1 +Cc1nc(C(=O)N(C)C(C)c2cccs2)nn1-c1ccc(F)cc1 +N#Cc1ccc(CSc2nnc(C3CC3)n2C2CC2)cc1 +CCCCS(=O)(=O)N1CCCC1C(=O)NC1CCCCC1 +Cc1ccc(NC(=O)c2cc(F)c(F)c(F)c2)cc1S(C)(=O)=O +Cc1ccc(CC(=O)N(CCC#N)CCC(F)(F)F)cn1 +Cc1ccc(Cn2nnc(CO)c2C(C)(C)C)cc1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(C)c(C(F)(F)F)c1 +O=C(NCCC1=CCCCC1)c1cc2cc(F)ccc2[nH]1 +CC(C)(C)Oc1cc(CNC(=O)CCC2CCCOC2)ccn1 +CCOC(=O)CCCNC(=O)Nc1c(C)cccc1C +C#CCNC(=O)c1ccc(Cl)cc1NC(=O)c1ccoc1C +Cc1cnc(C(=O)OCC(=O)c2ccccc2)cn1 +Cc1nnc(SCC(=O)NC2CCCC2)n1-c1ccccc1 +CC(=O)c1cc(Cl)ccc1OCC(=O)Nc1nccs1 +CC(C)CC1COCCN1Cc1cnc(-c2ccccn2)s1 +CCC(CO)NC(=O)CC(c1ccccc1)c1ccccc1 +CCCN1C(=O)C(O)(C2COC(C)(C)CC2=O)c2ccccc21 +O=C(NCCCn1cccc1)c1ccccc1Cl +Cc1cc(NC(=O)CN2CCN(c3ccc(Cl)cc3)C2=O)no1 +CC(C)C(=O)N1CCN(C(=O)c2c(Cl)cccc2Cl)CC1 +CCN(CC)C(=O)Cn1cnc2ccc(Br)cc2c1=O +CC(C)Oc1cccc(C(C#N)N2CCOCC2)c1 +Cc1nnc2c(NC(=O)c3cc(F)ccc3F)cccn12 +NC(=O)c1cc(Cl)ccc1NC(=O)CCCOc1ccccc1 +NC(=O)Nc1cccc(C(=O)NCc2nnc3ccccn23)c1 +O=C(Cn1nnc(-c2cccs2)n1)NCC1(c2ccccc2)CC1 +Cc1ccccc1C(=O)NC(C(=O)N=c1[nH]cn[nH]1)C(C)C +CCC(CC(=O)N1CCC(C(=O)OC)c2ccccc21)C(C)C +Cc1ccc(CNc2ncc(Br)cc2N)s1 +Cn1ccnc1SCc1nc(C(C)(C)C)no1 +Cc1nc2ccccc2c(=O)n1-c1c(C)n(C)n(-c2ccccc2)c1=O +Cc1[nH]c2ccccc2c1C(=O)NCC1CN2CCCC2CO1 +CN(C)C(=O)c1ccc(NC(=O)CSc2ccc(F)cc2)cc1 +Nc1ccccc1C(=O)N1CCOc2ccccc21 +O=C(c1cnc2n(c1=O)CCS2)N(Cc1ccco1)C1CC1 +CC(C)C1Oc2ccc(C(=O)C3CCCCN3)cc2NC1=O +Cc1cc(C(=O)N2CCC(OCc3ccccc3F)CC2)[nH]n1 +COc1cc(C#N)ccc1OC(=O)Cc1cccc(C(F)(F)F)c1 +Cn1cc(Cl)cc1C(=O)Nc1cnc(-c2ccccc2)nc1 +COc1ccc(C(O)CCNc2ccccc2F)cc1OC +Cc1cccc(C(=O)OCCOc2ccc(C#N)cc2)n1 +CCOC1COCC1NC(=O)c1cc(C)c(CC)n(C)c1=O +CCCCC1CCC(C(=O)N2CCC(Oc3cccnn3)CC2)CC1 +O=C1Cc2cc(C(=O)CSc3nnc4ccccn34)ccc2N1 +O=C(c1ccn(C(F)F)n1)N1CCC(C(O)Cc2ccccc2)CC1 +CC1CCN(C(=O)c2csc(-c3cnn(C)c3)n2)C(C)C1 +Fc1ccc(-c2cnc(CNc3ccc(-n4cncn4)cc3)o2)cc1 +Cc1ccc(C)c(S(=O)(=O)NCC(C(C)C)N2CCOCC2)c1 +CCC(C)(CO)NC(=O)Nc1cccc(C)c1Cl +COc1ccc(Cl)cc1NC(=O)c1nnn(-c2ccccc2)c1C +CCC(CNC(=O)C1CCC(=O)N1)Oc1ccccc1Cl +CCN(C(=O)Cn1cnc2cc(F)c(F)cc21)C1CC1 +O=C(NCc1ccccc1C(F)(F)F)c1scc2c1OCO2 +Cn1cc(C(=O)NCC(=O)Nc2ccccn2)c(C(C)(C)C)n1 +Cn1cc(C(=O)NCC(=O)Nc2ccc(F)cc2)c(C(C)(C)C)n1 +COc1cc(OC)cc(C(=O)Nc2ccc(OC(C)=O)cc2C)c1 +CCS(=O)c1ccccc1C(=O)NCC1CCCC(C)C1 +COCc1cc(=O)[nH]c(NCc2cccc(Br)c2)n1 +Cc1ccc2cc(NC(=O)c3ccco3)ccc2n1 +O=C(NCC#CCN1CCc2ccccc2C1)c1ccno1 +CS(=O)(=O)c1ccc(-c2cc(O)cc(Cl)c2)cc1 +CC(CCc1ccc2c(c1)OCO2)OC(=O)C1COCCO1 +COc1cc(C(=O)N2CCCC(c3nncn3C)C2)cc(OC)c1C +CNC(C)C1NCCc2cc(Br)c(O)cc21 +CN(CCC#N)S(=O)(=O)NCC(C)(C)c1ccc(Cl)cc1 +CC1=C(C)C(O)N(C(C)CCc2ccccc2)C1=O +Cc1nn(CC(=O)NCc2ccco2)c(=O)c2ccccc12 +Cc1noc(C2(C)CCN(c3cnccn3)CC2)n1 +CN(c1ccc(F)c(N)c1)S(=O)(=O)c1cccc(Cl)c1 +CCOC(=O)CN(C(=O)c1ccc(C(C)(C)C)cc1)C1CC1 +CCOC(=O)CN(C)S(=O)(=O)c1cn(C)c(C)n1 +O=C(c1cc(Cl)ccn1)N1CCCC2CCCCC21 +CCN(CC)c1nc(N)c(C(=O)NC(C)C)s1 +COc1ccccc1C(=O)NCCNc1cccc(F)c1C#N +Cc1occc1-c1nnc(SC(C)C(=O)N(C)CCC#N)o1 +C=CCOCC1CC2OCCN(C(=O)Cc3ccccn3)C2C1 +COc1cc(C)ccc1OCC(=O)Oc1ccccc1C +O=C(Cc1ccc(F)c(F)c1)Nc1ccc(F)c(F)c1 +O=C1CCc2cc(NC(=O)NC3CCCCC3)ccc2N1 +CN(C)S(=O)(=O)c1cccc(CSc2nncn2C)c1 +NC(=O)COc1cccc(COc2ccccc2F)c1 +CC(C)CCn1c(CO)cnc1S(=O)(=O)CC(C)C +CCOc1ccccc1-c1nc(-c2nnn(-c3ccccc3)c2C)no1 +Cc1nccn1-c1ccc(NC(=O)CC2C=CCC2)cn1 +O=C(NCCCn1cccn1)c1cc2c(s1)CCC2 +COc1ccc2c(ccn2CC(=O)NCc2nnc3ccccn23)c1 +CCC(C)CSc1nnc(C2CCOCC2)n1N +CCn1cc(CN(C)C(=O)Nc2ccc(OC)c(C(=O)NC)c2)cn1 +Cc1noc2nc(C3CC3)cc(C(=O)N=c3[nH]ccn3CC(C)C)c12 +NC(=O)n1c2ccccc2c(=O)c2cc(Cl)ccc21 +COc1ccccc1N1CCN(CC(=O)NC2CC2)CC1 +Nc1ccc2[nH]c3nnc(-c4cncc(Br)c4)n3c2c1 +CCCCc1nnc(NC(=O)c2ccc(-n3ccnn3)cc2)s1 +Cc1ncsc1CCOC(=O)c1scnc1C1CC1 +O=C(COC(=O)Cn1nnc2ccccc21)NC1CCCC1 +CC(=O)c1ccc(C#N)c(SCC(=O)Nc2ccccc2Cl)n1 +CC(NC(=O)c1cncc(Br)c1)c1ccccc1N +Cc1ccc(CCc2ncc3c(n2)CCCC3)cc1N +N#Cc1c(F)cccc1NCc1csc(C2CC2)n1 +Nc1cccc(Cl)c1Sc1nnc2n1CCCCC2 +CS(=O)(=O)NCC1CCCCN1C(=O)NCCC1=CCCCC1 +CCOCCCN1CC2=C(C1=O)C(c1cccc(C)c1)NC(=O)N2 +C=CCOc1cccc(NC(=O)c2scnc2C)c1 +Cc1cc(=O)c(CO)nn1-c1ccc(Br)cc1 +CCC(C)NC(=O)Nc1ccc(C)c(S(=O)(=O)N(CC)CC)c1 +N#CCC(=O)Nc1ccc(C(=O)OCc2cccc3ccccc23)cc1 +CN(Cc1ccccn1)C(=O)NC1CCc2c(F)cccc21 +N#Cc1ccc(N2CCN(Cc3ccc(-n4cccc4)cc3)CC2)nc1 +N#CCOc1cccc(CC(=O)Nc2cccc3c2C(=O)NC3)c1 +O=C(CNC(=O)N1CCCC1c1ccsc1)N1CCCCC1 +COc1ccc(CCNC(=O)C(C)C)cc1OC +COc1c(C)cc(C)cc1NCCN1CCOCC1 +CC(C)CC1COCCN1CC(=O)Nc1nc(-c2ccco2)cs1 +Fc1ccc(OC2CCN(Cc3cnc4ncccn34)CC2)c(F)c1 +O=C(Nc1ccccc1-n1cncn1)c1ccnc2ccccc12 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)Nc1cccc2cn[nH]c12 +Cc1cc(C)c(C(=O)NCCc2c(Cl)cccc2Cl)c(=O)[nH]1 +CC(C)n1cc(CN(C)C(=O)Cn2c(=O)cnc3ccccc32)cn1 +Cc1oc2ncn(C)c(=O)c2c1C(=O)N1CCCC1 +Cc1cc(C)c2sc(NC(=O)c3cnccn3)nc2c1 +O=C(c1cscn1)N1CCOCC(Cc2cnccn2)C1 +COc1cc(OC)cc(OCCN2CCC(=O)CC2)c1 +CCN(CC)C(=O)CCCNC(=O)NC1CCCC1 +COc1ccc(-c2nc(-c3ccccc3)no2)cc1N +CC(NC(=O)Nc1ccncc1)c1ccc(F)cc1 +CC(Oc1ccc(F)cc1)C(=O)Nc1ccnn1Cc1ccco1 +Cc1oc2c(c1-c1csc(NCC(C)C)n1)CCC2 +COc1ccccc1-n1nnc(C#N)c1-c1ccccc1F +Cc1nc2ccc(N(C)C(=O)c3ccccc3-n3ccnn3)cc2s1 +Cc1cc(C)c2c(n1)oc1c(=O)n(CC(=O)N3CCCCC3)cnc12 +Cc1cccc(NC(=O)c2ccc(-n3nc(C)cc3C)cc2)n1 +Cc1ccc(C)c(SCC(=O)Nc2nccs2)c1 +O=C(NCc1ccccc1)Nc1ccccc1Cl +Cn1ccc(NC(=O)c2cc(-c3cccs3)nc3ccccc23)n1 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1cccnc1 +CC(O)CN1CCN(CCOc2ccc(C(C)(C)C)cc2)CC1 +Cc1ccc(NC(=O)N2CCC(CCn3cccn3)CC2)c(C)n1 +Cc1cc(C)n(-c2nc(C)c(C(=O)Nc3c(C)cccc3C)s2)n1 +Cc1cc(N2CCC(=O)CC2)nc(-c2ccc(Cl)cc2)n1 +Cc1ccc(C)c(C(=O)N2CCn3cccc3C2C)c1 +CC(C)n1cnnc1SCC(=O)Nc1cccc(F)c1 +N#CCC(=O)Nc1cc(Cl)cc(C(F)(F)F)c1 +Cc1cc(C)n(CCNC(=O)c2cc(NC(=O)C3CC3)n(C)n2)n1 +FC(F)n1ccnc1COc1nc(-c2ccccc2Cl)no1 +COc1ccc(OCC(=O)Nc2ccc(C)cc2O)cc1 +CC(C)C(=O)NC1CCN(c2ccccc2C(=O)N2CCCC2)CC1 +CCn1c(N2CCC(C(=O)Nc3cccnc3)CC2)nc2ccccc21 +Cc1nc(C2CC(=O)N(c3ccc4c(c3)OCO4)C2)no1 +CN(C(=O)COCC1CCCO1)c1cccc2ncccc12 +Cc1cc(C2CCC2)nc(N2CCC(CN3CCOCC3)CC2)n1 +O=C(NCc1cccc(C(F)(F)F)c1)c1ccc(-n2cncn2)cc1 +O=C(NCc1cccnc1)c1cc2c(ccc3ncccc32)s1 +COCCNC(=O)CCn1c(=O)c(C)nc2ccccc21 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCCNc1ncccn1 +COc1ccc(-c2ncncc2-c2ccccc2OC)c(O)c1 +CN(Cc1cc(Cl)cc(Cl)c1)C(=O)CCn1cncn1 +Cn1ncc2c(NCCCOc3ccccc3)ncnc21 +CC(NC(=O)COc1cccc(-n2cnnn2)c1)c1ccccc1 +CC(Oc1cccc(Cl)c1)C(=O)Nc1ccc(C#N)cn1 +O=C(COc1ccc2ccc(=O)oc2c1)N1CCc2ccccc2C1 +c1csc(-c2n[nH]cc2CN2CCc3ccccc32)c1 +CCOc1ccccc1-n1nnnc1SC1CC(C)OC1=O +Cc1c(CO)nnn1-c1cc(Cl)cc(Cl)c1 +CC(C)(C)c1nnc(NC(=O)NCC2CCCC2)s1 +O=C1CCSc2c1cccc2C(=O)Nc1ccc(F)cc1 +CCn1cnnc1CNS(=O)(=O)c1ccc(OC)c2ccccc12 +CCOC(=O)c1nc[nH]c1C(=O)Nc1ccccn1 +CS(=O)(=O)N1CCC(CNC(=O)c2ccc3ccccc3c2)CC1 +CCOC(=O)c1c(C)nc2nc(-c3cccc(Cl)c3)nn2c1C +C=CCn1cccc(C(=O)Nc2ccc(C)c(C)c2)c1=O +CC(C)C(C#N)N(C)S(=O)(=O)c1ccc2c(c1)OCO2 +Cc1ccc2nc(C)cc(C(=O)NC(C)Cc3cc(C)n[nH]3)c2c1 +O=C(c1csc(CCc2ccccc2)n1)N1CCCCC1 +CCCOc1cccc(C(=O)NCC2(C(N)=O)CCOCC2)c1 +O=C(CCN1CCCC1=O)OC1CCCc2ccccc21 +Cc1cc(C(=O)Nc2ccc(Cl)cn2)sc1C +CC1CC(C)CN(C(=O)c2ccccc2NC(=O)NC2CCCC2)C1 +CCS(=O)c1ccccc1C(=O)NCc1cnc(C)s1 +CCCOc1ccc2c(c1OCC)C(CC#N)NCC2 +N#Cc1cccc(S(=O)(=O)NCc2nccs2)c1 +CC1CCN(C(=O)c2ccco2)c2ccccc2S1 +Fc1ccc2c(c1)CCN(Cc1nc(-c3ccsc3)no1)C2 +CCOc1ncccc1CNC(=O)NC(CC)CC +CC1COc2cc(Cl)cc(Cl)c2N(C)C1=O +NC(=O)CN1CCCCC1c1nc2ccccc2s1 +COC(=O)c1c(N)n(C2CCCC2)c2nc3ccccc3nc12 +O=C(Cc1ccccc1)N1CCN(S(=O)(=O)C2CC2)CC1 +CC(NC(=O)Cn1cc(C(F)(F)F)ccc1=O)c1ccc(F)cc1 +Cc1ccc(SCC(=O)Nc2cccnc2)cc1 +CNc1ccccc1S(=O)(=O)Nc1cnccc1C +C#CCN(c1nccs1)S(=O)(=O)c1sccc1OC +CC(CC(=O)N(C)C1CC1)NC(=O)c1ccccc1 +Cc1cc(=O)c(C(=O)N(Cc2ccccc2)C(CO)C(C)C)c[nH]1 +Cc1ccc(NC(=O)Nc2ccccc2OCC2CC2)cc1C(N)=O +O=C(Cc1csc(NC(=O)c2ccccc2)n1)Nc1ccon1 +CC(C)C(=O)Nc1cccc(C(=O)Nc2ccc(F)cc2)c1 +O=C(c1noc2c1CCCC2)N1CCC(Oc2ccccc2)CC1 +COc1ccccc1NC(=O)N(Cc1ccco1)Cc1ccco1 +O=C(Nc1ccc2c(c1)OCCO2)c1ccc(F)c(F)c1F +CCc1nc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)sc1C +Cc1cccc(NC(=O)NC(C)C)c1NC(=O)C(C)(C)C +O=C(c1ccc(N2CCNC2=O)cc1)N(CCO)Cc1ccccc1 +CCc1onc(C)c1NC(=O)c1ccnc(SC)c1 +O=C(CSc1nnc(-c2ccccc2)o1)Nc1ccc(Cl)cn1 +O=C(CNCC(F)(F)F)N1CCCC1CN1CCOCC1 +O=C(CNC(=O)C1CCCc2ccccc21)OCc1ccccc1 +O=C(NCC1(COc2cccnc2)CC(O)C(O)C1)C1CCCC1 +CC(C)CCC(C)NC(=O)Cn1cnc2ccccc2c1=O +O=C(NC1CCCC1)c1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +Cc1ncc(C)c(N2CCc3onc(-c4ccc(Cl)cc4)c3C2)n1 +CC(C)CN(Cc1ccccn1)C(=O)c1nn(C)cc1Cl +Cc1ocnc1C(=O)NC(CC(F)(F)F)c1ccc(Cl)cc1 +CNC(=O)c1nc(N2CCCC2)c2c(C)scc2n1 +CC(C)NS(=O)(=O)c1cccc(C(=O)Nc2cccc(C#N)c2)c1 +Cc1cc(C)cc(C(=O)NCC(=O)Nc2nc(C)cs2)c1 +O=S(=O)(c1ccccc1Cl)N(CCO)C1CC1 +Cc1nc(-c2cccc(NCc3ccc(F)cc3)c2)n[nH]1 +CCOC(=O)c1c(C)nn(-c2ncccc2C(F)(F)F)c1C +C#CCN(C)c1c(N)n(CCCC)c(=O)[nH]c1=O +N#Cc1cc2ccccc2nc1NCCCOC1CCOC1 +O=C1CCC(NC(=O)Nc2cccc3c2OCCO3)CN1 +OCC#Cc1cc(COCC(F)(F)F)ccc1F +COCCOc1ccc(CN2CCNC(=O)C2c2ccccc2)cc1 +CCN(Cc1ccco1)S(=O)(=O)c1ccc(C(N)=O)cc1 +COc1ccc2nc(-c3ccc(Cl)c(NC(=O)C4CC4)c3)cn2n1 +Cc1ccc(-c2cc(=O)[nH]c(Cc3ccccc3)n2)cc1N +Cc1n[nH]c(C(=O)N(C)CCc2ccccn2)c1Br +CCOc1ccccc1C1Nc2ccccc2C(=O)N1C(C)C +COCc1nc(C(=O)N2CC(C)(C)Sc3ccccc32)cs1 +COCC(NC(=O)NCC1CN2CCCCC2CO1)C1CC1 +O=C1CCCc2cc(NCc3ccc4c(c3)OCCO4)ccc2N1 +CN1CCN(C(=O)C2CCN(C(=O)C(C)(C)C)CC2)CC1 +Cc1c(C(=O)NCc2ccccn2)oc2ccccc12 +COCCN1CC(C(=O)Nc2ccc(F)cc2)CC1=O +Cc1ccc(C)n1-c1c(C(=O)N(C)CCc2ccncc2)cnn1C +Nc1ccc(Cl)cc1NC(=O)Nc1ccccc1 +Cc1nn(C)c2nc(NCC3CCCN(C(=O)C4CC4)C3)sc12 +COc1cc(OC)cc(OC2(C(N)=O)CCCCC2)c1 +C=CCNc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccc(F)cc1 +O=C(NCc1ccccn1)c1nc(-c2ccc3[nH]ccc3c2)no1 +O=C(COC(=O)COc1ccccc1)Nc1ccc(F)c(F)c1F +CC(C)(C)OC(=O)NCCCNC(=O)c1cc(F)ccc1F +C=CCNC(=O)c1coc(CN2CCN(c3ccccc3C)CC2)n1 +CC(C)(C)CC(=O)NCC1CCN(S(=O)(=O)C2CC2)CC1 +NC(=O)c1ccc(COc2ccccc2Br)cc1 +COc1ccccc1C(O)CCNc1cccc(C)c1 +COCC(C)CNC(=O)c1cc(C(C)C)n(C(C)(C)C)n1 +COc1ccc(C)cc1NS(=O)(=O)c1cc(F)cc(F)c1 +CC(C(=O)N1CCCC1)S(=O)(=O)c1ccc2ccccc2n1 +CC(C)c1nc(CN(C)Cc2cnc(-c3ccco3)nc2)no1 +COc1ccc(Cl)cc1NC(=O)c1cnc(C)cn1 +Cc1cc(C)n(-c2cccc(NC(=O)Cc3noc4ccccc34)c2)n1 +Cc1ccc(Oc2ccc(S(C)(=O)=O)cc2)cc1 +CCC(NC(=O)CCC(=O)OC)c1ccc(C)cc1 +CC(C)c1n[nH]c(SCCCN2CCCC2=O)n1 +CCOC(=O)NCC1CCN(C(=O)c2cnccn2)CC1 +CCn1c(C(=O)Nc2ccccc2O)cc2ccccc21 +CS(=O)(=O)N1CCCc2ccc(NC(=O)C3CCCCC3)cc21 +O=C(CCCS(=O)(=O)Nc1ccccc1)Nc1ccccc1 +CSc1ccccc1C(=O)NCCN(C)c1ccccc1 +CCN(CC1CC1)C(=O)c1ccc(S(C)=O)cc1 +Cc1ccc(O)c(C(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)c1 +Cc1ccnc(NC(=O)CCc2c(C)n[nH]c2C)c1 +Cc1cccc2[nH]c(C3CCCN(C(=O)c4c[nH]c(=O)cn4)C3)nc12 +COc1ccc(NC(=O)CCC(=O)c2ccc(C)s2)cc1OC +Cc1noc(C)c1CCC(=O)Nc1ccc(OC(C)C)nc1 +CSc1ccc(NC(=O)C(C)Sc2ncn[nH]2)cc1 +CC(C)Cc1nnc(NC(=O)C2Cc3cc(Cl)ccc3O2)s1 +Cc1ccc(Cl)cc1NC(=O)COc1cccc2ccc(=O)[nH]c12 +COc1cccc(-c2nc(CC(=O)NC3CCCCC3)no2)c1F +c1csc(CN(Cc2nc(C3CC3)no2)CC2CCCO2)c1 +CN(CC(=O)NCCNc1ncccn1)S(C)(=O)=O +CC(CCC1CCCC1)NS(=O)(=O)c1cc(C(N)=O)n(C)c1 +NC(=O)CC1CCN(C(=O)c2ccccc2C(F)(F)F)CC1 +O=C(CNC(=O)c1ccccc1F)Nc1cccc(-n2cnnc2)c1 +Cc1ccc(C(=O)NCC(=O)NCc2cnn(C)c2C)cc1C +COCc1nc(C)cc(NC2CCSc3ccc(F)cc32)n1 +CCC(C)(CNC(=O)C(C)n1cncn1)N1CCOCC1 +CCOCCCNC(=O)c1n[nH]c2ccc(C)cc12 +Cc1cc(NC(=O)COc2ccccn2)ccc1Br +CCN(CCn1cccn1)C(=O)Cn1ncc(N(C)C)cc1=O +c1ccc2oc(-c3noc(-c4ccn[nH]4)n3)cc2c1 +O=C(Cc1ccc[nH]1)Nc1ccc2c(c1)OCCO2 +CNC(=O)c1cccc(C(=O)N(CCC#N)CCC(F)(F)F)c1 +O=C(NCc1ccncc1)c1cnn(-c2ccc(F)cc2)n1 +COCC(O)CNC(=O)NC(C)Cc1ccccc1Br +Nc1ccccc1OCCc1nc2ccccc2[nH]1 +Cc1ccc2[nH]cc(-c3cc(C(=O)N4CCN(C)CC4)ccn3)c2c1 +Cc1ccc(NC(=O)N(C)Cc2ccoc2C)c(Br)c1 +Cc1cccc(C2CC2C(=O)N2CCN(C3CCCC3O)CC2)c1 +CS(=O)(=O)N1CCN(C(=O)Nc2ccccc2)CC1 +Cc1ccc(S(=O)(=O)NCc2ccc(OC3CCCC3)nc2)cc1 +CC(=O)c1sc(-c2ccc3[nH]c(=O)oc3c2)cc1N +CC(=O)N1CCC(C(=O)Nc2cc(CC3CCCCC3)n[nH]2)CC1 +CCCCOc1cccc(NC(=O)CNC(N)=O)c1 +O=C(NCc1ccco1)C1c2ccccc2Oc2ccccc21 +O=C(Oc1ccc2c(c1)OCCO2)c1ccc(Cn2cccn2)cc1 +O=C(NCc1cn2ccsc2n1)c1ccnnc1 +O=c1c2ccccc2ncn1CCOc1ccccc1 +COc1ccc(NC(=O)NCCCc2nnc3ccccn23)c(C)c1 +CCc1ncsc1C(=O)Nc1c(C)noc1CC +COC(=O)CCN1CCN(C(=O)c2cc3ccccc3[nH]2)CC1C +CC(C)n1cnnc1CNc1nc2cc(C(F)(F)F)ccc2s1 +Nc1ccc(NC(=O)c2ccc(F)cc2F)c(Cl)c1 +N#Cc1cc(-c2cc(Br)cs2)[nH]c1N +Cc1ccc(-n2nnc(C(=O)Nc3ccnc(C)c3)c2C)cc1 +COc1ccc(Cl)cc1NC(=O)C1CCCN1S(C)(=O)=O +CC(C)CN(CC(N)=O)C(=O)c1ccc(N(C)C)cc1F +CCC(CO)NC(=O)NCC(C)c1ccc(F)cc1F +Cc1cc(CNC(=O)CNc2ccccc2Cl)no1 +CC(C)N(C)C(=O)NCCCC(=O)Nc1ccc(Cl)cc1 +Cn1nc(C(=O)NCc2ncc[nH]2)cc1C(F)(F)F +Cc1cccc(N)c1NC(=O)COCCCC(C)C +O=C(NC1CCN(C(=O)C2CCCC2)C1)c1ccc(O)cc1F +COC(=O)c1cc(Br)cn2nc(N)nc12 +COc1ccc(SCCC(=O)N2CCC(C(N)=O)CC2)cc1 +CCc1noc(NC(=O)Cn2ncc(N3CCCC3)cc2=O)c1CC +Cc1csc(-c2cccc(NC(=O)N3CCOC(C)(C)C3)c2)n1 +O=C(NCCN1CCOCC1)NCc1cccc(N2CCCC2=O)c1 +Cc1ccc(-c2nsc(SCC(=O)Nc3nccs3)n2)cc1 +Cc1noc(C)c1CN(C)C(=O)C1CCCN1C(=O)C(C)C +CC(=O)N(C)CC(=O)NC1CC(=O)N(C)C1c1ccc(Cl)cc1 +CC(=O)N(C)c1ccc(NCC(=O)Nc2ccccc2C(N)=O)cc1 +COC(=O)CNC(C#N)c1c(Cl)cccc1Cl +CCCCNC(=O)c1nn(-c2ccccc2C)c(=O)cc1OC +CCn1cc(NCc2ccc(OC)c(O)c2)c(C)n1 +COC(=O)Cn1c(-c2cccs2)nc2c(N)cccc21 +CCN(Cc1cccc(C)c1)C(=O)NCc1ccco1 +CC(Oc1ccc(Br)cc1)C(=O)Nc1ccccc1N +CCC(C)n1nccc1NC(=O)c1ccc(OC)c(OC)c1 +CCN(CC)C(=O)CSc1nc2cccnc2n1C +CCCC(=O)N1CCCC1C(=O)OCc1cccc(OC)c1 +Cc1ccc(-c2nc(Cn3cnc(C4CCC4)cc3=O)cs2)o1 +COc1ccc(SC(C)C(=O)Nc2nncs2)cc1 +CCc1onc(C)c1NC(=O)C(C)C1CCOCC1 +CC(C)(C)OC(=O)N1CCCC1c1cc(N)ccc1Cl +CC(CO)NC(=O)c1cn(-c2ccccc2)nc1-c1cccs1 +COc1cccc(OC)c1C(=O)n1nc(C)cc1C +O=C1c2cccnc2CN1Cc1n[nH]c2c1CCC2 +Fc1nc(F)c(F)c(C#Cc2ccccc2)c1F +CC(NC(=O)c1cn(C)nc1C(C)(C)C)c1ccccc1 +COc1cccc(C(=O)NCC(=O)Nc2ccccc2)c1O +O=C1NCCCc2[nH]c(-c3ccc4[nH]c(=O)[nH]c4c3)nc21 +N#CCc1ccc(OCC(=O)Nc2ccc(F)cc2)cc1 +COCCN(Cc1ccccc1)C(=O)C1CC(=O)N(C)C1 +Cc1csc(C2CCCCN2C(=O)CC(C)n2cccc2)n1 +Cc1noc(C)c1CC(=O)N1CCN(C(C#N)c2ccccc2)CC1 +Cc1ccc(OCCc2cnc3c(C#N)cnn3c2)cc1C +CC(C)(CNC(=O)Nc1cccc(C(N)=O)n1)c1ccncc1 +O=C(Cn1cncn1)Nc1ccc(-c2nc3c(F)cccc3[nH]2)cc1 +Cc1nc2ccc(C(=O)n3nc(N)c4ccccc43)cc2nc1C +O=C(NCCCO)c1cccc(Oc2cccc(C(F)(F)F)c2)c1 +Cc1ccc(C)c(NC(=O)c2nc(-n3ccnc3)ncc2Cl)c1 +Cc1nn(CCc2nnc(-c3ccc4c(c3)OCO4)o2)c(C)c1Cl +O=C(COC(=O)Cc1cccs1)Nc1ccc2c(c1)CCC2 +Cc1noc(C)c1C(=O)N1CCC(c2nc3ccccc3s2)CC1 +CCN(C)C(=O)c1cnc(Cc2ccc(F)cc2)s1 +NC(=O)c1cccc(COC(=O)C2CC(=O)N(Cc3ccco3)C2)c1 +COc1cc(OC)cc(-c2nnc(NC(=O)C(C)C)o2)c1 +Cc1ccc(N2CC(C(=O)N(C)Cc3c(C)noc3C)CC2=O)cc1 +CNC(=O)c1cccc(NCC(=O)NCCc2ccccc2)c1 +CCCCC(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +COCC(C)NC(=O)c1cn(Cc2ccc(Cl)cc2)nn1 +Cc1ccc(C(=O)Nc2ccc3c(c2)OCO3)cc1N +Cc1ccnc(NC(=O)COc2ccc(Br)cc2F)c1 +CCOc1ncccc1CNS(=O)(=O)N1CCCC(C)C1 +CSc1nccn1-c1cccc(C(=O)OCC(=O)NC(C)C)c1 +COc1ccc(NC(=O)c2c(C)n[nH]c2N)c(C)c1 +CCC(=O)Nc1cccc(NCc2cc(OC)cc(OC)c2)c1 +CCOC(C)c1noc(COc2nc(C(C)C)no2)n1 +Cc1oc(C2CCC2)nc1C(=O)N1CCCc2ccccc21 +CN(C)c1c(Cl)cccc1NC(=O)NCc1nnc2ccccn12 +Cc1ccc(C(=O)N2CCn3c2nc2ccccc23)cc1 +Cc1nc(Cc2ccccc2)sc1C(=O)NCC(=O)NC1CC1 +CCOc1ccc(S(=O)(=O)NCC2(O)CCc3ccccc32)cc1 +CC(NC(=O)OC(C)(C)C)C(=O)N(C)CC(O)C1CC1 +CCC(C)Oc1cccc(C(=O)NCc2ccco2)c1 +COc1cccc(-c2cc(C(=O)NC3CC3)n(C)n2)c1 +Cc1noc2nc(C(C)C)cc(C(=O)N(C)c3nccs3)c12 +CC(=O)Nc1ccc(NCC(=O)N2CCCCC2)cc1 +Cc1ccnc2nc(C(=O)N3CCCc4c(Cl)ccc(F)c43)nn12 +CC(=O)NCCCOc1cc(Cl)ccc1C(N)=O +CCn1cc(C(=O)Nc2ccc3oc(C4CC4)nc3c2)cn1 +N#CCCN1CCc2c(cccc2NC(=O)Nc2ccccc2)C1 +Cc1cc(Cl)c(C(=O)NC(C)CCN2CCCC2=O)cc1C +Cc1cc(CNC(=O)c2ccccc2S(=O)(=O)C(C)C)ccc1F +CSc1nc(C)cc(C(=O)NCCc2ccco2)n1 +COc1cn(CC(=O)NCC2CC3C=CC2C3)c(CO)cc1=O +CCC1CCCN(C(=O)c2cc3cc(F)ccc3[nH]2)C1 +Cn1ncc(N2CCCC(C3(C)OCCO3)C2)c(Cl)c1=O +O=C(NCc1cccc(F)c1)c1ccn2cncc2c1 +O=C1COc2ccc(NS(=O)(=O)c3cn[nH]c3)cc2N1 +C=CCN1CC2(CCC1=O)CCN(C(=O)c1ccccc1C#N)CC2 +Cn1nnnc1SCc1ccc(OC(F)F)cc1 +Cc1cccc(COc2ccc3c(c2)OCC3O)c1 +CCNC(=O)CN(CC)C(=O)COc1ccc(F)cc1F +O=C(Nc1ccc(N2CCCC2)nc1)c1ccc(C(F)(F)F)cc1 +CC(=O)NC(C(=O)NC(C1CC1)C1CC1)C1CCCC1 +Cc1nn(C)c2nc(NCc3cnn(Cc4ccccc4)c3)sc12 +Cc1nc(C)n(CCNC(=O)C2CC(=O)N(C3CCCC3)C2)n1 +CCc1cccc(C)c1NC(=O)Cc1ccc(OC)cc1 +NC(=O)c1ccc(NC(=O)c2nccc3ccc(N)cc23)cc1 +COC(=O)CC1CCCCN1C(=O)c1cc(C2CC2)on1 +CC(C)COC(=O)CN1CC(C)Oc2cccc(N)c21 +NC(=O)COc1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +Cc1cc(C(=O)Nc2sc3c(c2C(=O)NC2CC2)CCC3)on1 +O=C1N(CCOc2ccccc2)c2c(Cl)cccc2C12OCCO2 +Cc1c(N)cccc1C(=O)Nc1cccc(Br)c1 +CC1CCCCN1C(=O)c1cn(C)c2cccc(N)c2c1=O +Cc1cccc(C(C)C)c1NC(=O)c1nn(C)c(C)c1Cl +COc1ccc(NC(=O)NC(C)c2ccncc2)c(OC)c1 +O=C(Cn1ccccc1=O)N1CCCC1c1cccc2ccccc12 +CCS(=O)(=O)N(Cc1ccccc1C#N)c1ccc(C(C)=O)cc1 +CCn1cc(CN(C)C(=O)c2ccc(-c3ccccc3)cc2)cn1 +CC(=O)Oc1cccc(C(=O)Nc2ccc(C)c(C)c2)c1 +O=S(=O)(NCc1ccccc1)c1ccc2c(c1)CNCC2 +O=C(Cc1ccc[nH]1)N1CCOC(C2CCCO2)C1 +CCOC(=O)c1cc(C(=O)c2ccccc2)c2n(c1=O)CCN2C +Cc1noc(C)c1S(=O)(=O)NC(C)c1cccc(C(F)(F)F)c1 +CCc1cnc2c(c1NCCc1ccccc1)c(=O)n(C)c(=O)n2C +CC(C)(C)N1CC(C(=O)N2CCOCC2)CC1=O +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccc(F)c(F)c1 +CCc1noc(C)c1NC(=O)Nc1cc(-c2ncco2)ccc1C +COc1ccc(C)cc1S(=O)(=O)NCCC(O)C1CC1 +CCCCn1cc(C(=O)NCCC(C)C)c(=O)c2c(N)cccc21 +O=S(=O)(NCCc1cnn(-c2ccccc2)c1)N1CCOCC1 +COc1ccc(C#CCO)cc1NC(=O)CC1CC1 +Fc1cc(F)cc(OCc2noc(-c3cccs3)n2)c1 +NC(=O)c1cccc(C(=O)Nc2ccc(Cl)c(C(N)=O)c2)c1 +C=CCNC(=O)Nc1ccc(NC(=O)c2ccco2)cc1 +CNc1ncc(C(=O)OCC(=O)Nc2ccc(F)cc2Cl)s1 +Cc1csc(NC(=O)C2(c3cc(-c4ccccc4F)on3)CC2)n1 +CCN(CC)S(=O)(=O)N(C)C(C)c1ccccc1OC +COCCn1cc(NC(=O)NC(C)Cc2ccc(Cl)cc2)cn1 +Cc1c(C(=O)NCCC2=CCCCC2)sc2nc[nH]c(=O)c12 +CCc1ccc(C(C#N)N(C)C(=O)c2cccc(F)c2)cc1 +CCCn1nnnc1CN(C)S(=O)(=O)c1c(C)noc1C +CCc1ccc2nc(-n3ccc4c(cnc5ncnn54)c3=O)sc2c1 +Cc1noc(CNC(=O)CSc2nnnn2C)n1 +CC(=O)Nc1nc(C(=O)OC(C(C)(C)C)C(F)(F)F)cs1 +N#CC(NC(=O)c1ccco1)c1ccc2c(c1)OCO2 +CCOc1cc(-c2nc(-c3ccc(OC)cc3)n[nH]2)ccc1O +Cc1ccccc1CN(C)C(=O)CCNS(=O)(=O)c1cccnc1 +CC(C)(C)c1ccc(NC(=O)c2cnc(C3CCCO3)s2)nn1 +CCn1cc(C(=O)n2ccnc2)c2cc(S(=O)(=O)N(C)C)ccc21 +C#CCN1CCN(S(=O)(=O)c2cc(OC)ccc2OC)CC1 +CCOc1ccc(-c2nn3c(CC)nnc3s2)cc1 +CCN(CCO)C(=O)c1ccc(-c2cnco2)cc1 +CCCn1nnnc1CNc1ccc(C)c(Cl)c1 +CN(C)c1ccc(NC(=O)c2cccnc2OCC(F)F)cn1 +c1coc(-c2nnsc2-n2nnc3ccccc32)c1 +CC(=O)Nc1cc(NC(=O)NCc2ncoc2C)ccc1C +CC#CCCNS(=O)(=O)c1ccc(C(=O)NCC(F)(F)F)cc1 +CCN(Cc1cccs1)C(=O)Nc1nc(C)cs1 +COc1nccnc1COCC1CCCCN1C(=O)OC(C)(C)C +O=C(c1ccc[nH]1)N1CC(OCc2cccnc2)C2COCC21 +COc1cn(C)c(C(=O)NCc2ccc(F)cc2)cc1=O +Nc1cccc(CSc2nc3ccccc3[nH]2)n1 +COc1ncccc1CNC(=O)c1cc(C)ccc1F +O=C(Nc1ccc(C(=O)N(Cc2ccsc2)C2CC2)s1)C1CC1 +N#Cc1ccc(OCCOC(=O)CC2C=CCC2)cc1 +CC(C)CCC(C)NC(=O)c1ccc2c(c1)OCC(=O)N2 +Cc1nc(C(=O)NCCC2CCCCN2S(C)(=O)=O)cs1 +CCC(=O)NC1CCCN(C(=O)Cc2ccc(F)c(F)c2)C1 +COC1CCCC1OC(=O)C1CC1c1ccc(F)cc1F +CC(C)n1nccc1C(=O)NCCc1ccncc1 +Cc1ccc(-c2nc3ccc(C)cn3c2CC(=O)N(C)C)cc1 +CC1CC(c2cccc(C#N)c2)Cn2nc(N)nc21 +CCN(CCC(=O)OC)C(=O)c1ccc(Br)cc1C +CC(C(N)=O)n1ccnc1-c1ccc(Cl)c(Cl)c1 +CCc1nc2cc(NC(=O)CCc3c(C)nc(C)[nH]c3=O)ccc2o1 +CCn1nnnc1SCC(=O)Nc1ccc(OC)cc1OC +Cc1nc2ccc(NC(=O)c3cnc4c(C)csc4c3)cc2s1 +N#Cc1cccc(-n2c(=O)[nH]c3cc(F)ccc32)c1 +CCOC(=O)c1nnsc1NC(=O)C(C)CC +CCCc1c(CO)nnn1-c1ccc2c(c1)OCO2 +N#Cc1nnn(-c2nccs2)c1CCOc1ccccc1 +Cc1ccc(NC(=O)N(C)CCc2c(C)nn(C)c2C)c(Cl)c1 +Cc1nnc2ccc(NCc3cccc4c3OCCO4)nn12 +CC(C)(CNC(=O)c1coc(-c2ccccc2)n1)c1ccncc1 +O=C(NCc1cn2cc(Cl)ccc2n1)c1c[nH]c2cccc(F)c12 +CC1CCc2c(C(=O)Nc3cn[nH]c3)csc2C1 +CCOc1ncccc1C(=O)N(C)c1ncnc2ccsc12 +COC(=O)c1ccc(F)c(NCC(=O)Nc2c(C)nn(C)c2C)c1 +COC(=O)Cc1sc(C)nc1C(=O)NC(C)(C)C +O=C(CSc1nnnn1Cc1ccccc1)Nc1ccccc1 +CC(=O)c1cn(S(=O)(=O)c2ccccc2)c2ccccc12 +CN(C)C(=O)Cc1ccccc1NCc1nnnn1-c1ccccc1 +CC(OCC(F)(F)F)C(=O)Nc1nnc(C2CC2)s1 +Cc1cc(C(=O)Nc2nc(-c3ccccc3)cs2)n(C)n1 +COc1cc(NC(=O)c2cc(C(C)C)on2)cc(OC)c1OC +O=C(NCc1cc(Br)cs1)c1scnc1C1CC1 +Cc1c[nH]nc1C1CCCN1C(=O)CN1CCOCC1 +CNC(=O)c1ccc(Cl)cc1NC(=O)CCOC(C)C +CC(=O)NC1CCCN(C(=O)Cn2cnc3c(cnn3C)c2=O)C1 +Cc1ccc(C(C)NS(=O)(=O)c2ccc(C)c(C)c2)o1 +CCC(CC)n1ncc(C)c1NC(=O)c1cncc(C)c1 +O=C(c1ccc2c(c1)OCO2)N1CCN(CC(O)c2ccco2)CC1 +CC(Cn1cccn1)NC(=O)NCC(O)c1ccc(F)cc1F +COc1ccc(CNC(=O)C2(C)Sc3ccccc3NC2=O)cc1 +NC(=O)C1CCCN1C(=O)c1csc(-c2ccccc2)n1 +CCCC(=O)Nc1ccc(NC(=O)c2ccco2)c(Cl)c1 +O=C(CC1CC1)N1CCc2ncnc(-c3ccsc3)c2CC1 +Cc1ccc(NC(=O)Cn2nc3ccccn3c2=O)c(C)c1 +CCOC(=O)C1CCCN(C(=O)c2cc3c(s2)CCCC3)C1 +CCCC1CN(C(=O)C(C)n2nnc(-c3ccccc3)n2)CCO1 +O=C(NCc1csc2c1CCCC2)C1CC(=O)N(C2CC2)C1 +CCOC(=O)c1sc(NC(=O)Cc2ccsc2)nc1C +Cc1nsc(N2CCCN(C(=O)c3sccc3C3CC3)CC2)n1 +Cc1ccc2c(cnn2CCC(=O)N(CCO)Cc2ccccc2)c1 +Cc1cc(C(=O)OC(C)C(=O)NC2CCCCC2C)c(C)o1 +Cc1nc(-n2cccc2)sc1C(=O)Nc1ccncc1 +CC(=O)N1CCN(C(=O)C(C)Oc2cccc(F)c2)CC1 +Nc1oc(C(F)(F)F)cc1C(=O)c1ccc(F)cc1 +CCNC(=O)NC1(C(=O)NCC2CCCO2)CCCC1 +Cc1ccccc1NC(=O)NC(C)c1ccc(-n2ccnc2C)cc1 +Cc1ccc(-c2nc(-c3cccnc3)no2)cc1C +Cc1csc2ncc(C(=O)NCC3CCCO3)c(=O)n12 +CCCNC(=O)C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1ccc(NCC(=O)Nc2nnc(C(C)C)s2)c(C)c1 +Cc1n[nH]c(SCCC(=O)N(C)Cc2ccc(F)cc2F)n1 +CN(CC(=O)Nc1ccccc1)C(=O)c1cc(F)cc2[nH]cnc12 +COc1ccc(NC(=O)NCc2ccnn2C)c(OC)c1 +CC(=O)NC(CC(=O)OCC(=O)N1CCCCCC1)c1ccccc1 +CCSc1ccc(C(=O)CCN2CCC(=O)CC2)cc1 +Cc1n[nH]c(C)c1-c1c[nH]c(C(=O)N2CCOCC2)c1 +C=CCNC(=O)c1ccc(NC(=O)C(C)CC)cc1 +Cc1cc(=O)oc2cc(Oc3ncccn3)ccc12 +Cc1nn(C)cc1-c1ccnc(NCC(C)Oc2cccnc2)n1 +Cc1nc(C)c(C(C)NC(=O)c2ccc3[nH]nnc3c2)s1 +CCOc1cc(C(=O)N(C)C)ccc1NCc1nnc(C2CC2)o1 +N#CC1(NC(=O)c2ccc3c(c2)OCC(=O)N3)CCCCC1 +Cn1cc(NC(=O)CCc2nc(-c3ccncc3)no2)cn1 +CS(=O)(=O)NCCCSc1ncn(-c2ccccc2)n1 +O=C(Cc1ccc(Cl)cc1)N1CCN(Cc2ccon2)CC1 +N#Cc1ccc(NC(=O)Cc2cc(Cl)c3c(c2)OCCCO3)cc1 +CCOC(=O)C1(N)CC1c1ccc(Cl)c(Cl)c1 +CCS(=O)(=O)NCCn1nc(-c2sc(C)nc2C)ccc1=O +CC(OC(=O)C1COc2ccccc2O1)C(=O)NC1CCCCC1C +CN(CCCc1ccco1)S(=O)(=O)c1csc(C(N)=O)c1 +O=C(NCC1CC=CCC1)NC1CC1c1ccccc1 +CC(=O)NCc1ccc(C(=O)NCC(C(C)C)N2CCOCC2)cc1 +Cc1cccc(NC(=O)c2c[nH]c3ccc(Cl)cc3c2=O)n1 +CCOC(=O)N1CCC(Nc2ncccc2C#N)CC1 +CCN1CCc2nc(NC(=O)c3cc(C)n(C)n3)sc2C1 +Cn1nc(-c2ccc3c(c2)CCCC3)cc(CC#N)c1=O +Cc1nnsc1C(=O)NCCn1nc(C(F)(F)F)cc1C1CC1 +COC1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1 +FC(F)(F)c1cccc(CNc2cncnc2)c1 +CC(=O)c1ccc(NC(=O)NC(C)C2CN(C)CCO2)cc1C +CC(C)N1CCN(C(=O)CC2Sc3ncccc3N(C)C2=O)CC1 +CC(=O)c1cccc(NC(=O)Cc2cccc(C)c2)c1 +CC(=O)Nc1ccc(NC(=O)Cc2c(C)[nH]c(=O)[nH]c2=O)cc1 +CC1CN(C(=O)c2ccc(OCc3ccncc3)cc2)CC(C)O1 +CCCc1nnc(NC(=O)N2CCN(C(=O)C(C)(C)C)CC2)s1 +COCc1ccc(CNC(=O)CSc2nc3ccccc3o2)cc1 +CCc1nnc(NC(=O)NC(C)c2ccc(C)cc2)s1 +Cc1ccc(N2CCC3(CC2)CNC(=O)CO3)nn1 +COC(=O)CCC(=O)Nc1cccc(-c2nnnn2C2CC2)c1 +CCc1c(C)nn(C)c1NC(=O)Cn1ccc2cccnc21 +CC(NC(=O)c1ccc(OCC(F)F)nc1)c1nc2ccccc2[nH]1 +Brc1ccc(Nc2cnns2)cc1 +CCn1cc(NC(=O)c2ccn(C(F)F)n2)c(C(=O)NC)n1 +CCc1cccc(C)c1NC(=O)c1cc2cc(OC)ccc2oc1=O +CCNC(=O)c1ccc(NCc2nc(-c3ccsc3)no2)c(C)c1 +CC(C)Oc1ccc(NC(=O)c2ccccc2NS(C)(=O)=O)cc1 +Cc1ccc(F)c(NC(=O)NCCc2cn3ccccc3n2)c1 +CN(C)C(=O)N1CCN(C(=O)NCc2nnc3n2CCCCC3)CC1 +C=CCNC(=O)C1CCN(S(C)(=O)=O)c2cc(Cl)ccc2O1 +CCCNC(=O)C1CCc2sc(C(=O)N(C)C)cc2C1 +CC(=O)Nc1ccccc1OCc1ccc(F)cc1 +CS(=O)(=O)c1ccc(OCc2ccc(Cl)cc2)cc1 +CCCN(C)C(=O)c1cc2c(nc3sccn32)s1 +Cn1nnc2cc(NC(=O)Nc3ccc(Br)cc3)ccc21 +O=C1COc2ccc(C(=O)COC(=O)c3ccco3)cc2N1 +Cc1nnc(SC(C)C(=O)NCc2ccc(F)cc2)n1N +C#CCN1CCC(C(=O)NCCCOC(C)C)CC1 +Cc1nccc(N2CCCC(C)(C(=O)NC3CCCC3)C2)n1 +CC(Cc1ccsc1)NCc1c(F)cccc1F +CCC(=O)N1Cc2ccc(C(O)c3ccccc3C)cc2C1 +CCc1nc(-n2nc(C)cc2C)nc(N2CCC(=O)CC2)c1C +CC1Cc2ccccc2N1CC(=O)Nc1cc(N)ccc1F +O=C(CCc1ccco1)N1CC(CO)C(CN2CCOCC2)C1 +N#CC1(NC(=O)Cc2ccccc2F)CCCCC1 +O=C(Nc1cccs1)Nc1ccccc1NC(=O)c1cccnc1 +Cc1ccccc1SCC(=O)NCCCc1cn[nH]c1C +CCS(=O)(=O)N1CCC(NC(=O)c2cccc(C)n2)CC1 +CSc1ccc(CN(C)C(=O)c2cnc(C)cn2)cc1 +Cc1nnc(-c2ccccc2C(=O)Nc2ccc(Cl)cc2)o1 +CCn1ncc2c1CCCC2NC(C)c1nc(C)no1 +CC1(C)CCC(CNC(=O)CCc2nnc(C3CCCC3)o2)CC1 +O=C(NCc1ccoc1)NC(c1ccc(F)cc1)C1CCCO1 +COc1ccccc1NC(=O)C1=C(C)NC(=O)NC1c1ccco1 +CCOc1ccccc1-c1cnn(C)c(=O)c1C(C)=O +N#CC1(C(=O)Nc2ccc(-c3cnco3)cc2)CCCCC1 +Cc1sc2nc3cc(N)ccc3n2c1-c1ccc2c(c1)OCCO2 +Cc1nn(C(C)C)c(C)c1NS(=O)(=O)c1cc(F)ccc1Cl +CC(=O)c1ccc(NC(=O)c2cccc3cc[nH]c23)cc1C +COC(C(=O)N1CCC(NS(C)(=O)=O)CC1)c1ccccc1 +CC(C)Oc1ccc(C#N)cc1NC(=O)C1CCCC1 +Cc1c(C(=O)OCC(C)C)sc2nc[nH]c(=O)c12 +COc1ccc(Cl)cc1C(=O)CCc1nccs1 +CC1(O)CCN(C(=O)c2ccccc2N2CCOCC2)CC1O +CNC(=O)c1ccccc1NC(=O)c1cccnc1 +Cc1cnc(N2CCN(CC(=O)Nc3ccc(F)cc3)CC2)nc1C +CCNc1ncccc1S(=O)(=O)NC(C)C1CC1 +Cn1ccnc1C(NC(=O)CCOc1ccccc1)c1ccccc1 +O=C1CC2CCC(CN1)N2Cc1cnc(N2CCOCC2)nc1 +O=c1sc2ccccc2c2c1ncn2-c1ccccc1 +CCCCOCCS(=O)(=O)c1ncccc1Br +O=C(c1ccncc1)N1CCCC(N2CCNC2=O)C1 +COc1ccc(OC)c(C(C#N)NC(=O)C(C)(C)C)c1 +C=CCOc1ccccc1CNc1ccc(-c2nc(C)cc(=O)[nH]2)cn1 +Cc1ccnn1-c1ccc(C(=O)N2CCCC2c2ccc(F)cc2)cc1 +O=C(CNC(=O)NCC(=O)Nc1ccccc1)NCc1ccco1 +CCc1cccc(C)c1NC(=O)CCC(=O)c1ccc(N)cc1 +CCc1nc2c(N)cccc2n1CC(=O)Nc1cccc(C)c1 +CC(C)(C)NC(=O)Cn1c(=O)n(Cc2ccco2)c2ncccc21 +CCn1cc(NC(=O)Cn2nc(C)c3ccccc3c2=O)ccc1=O +CC(=O)N(C)c1ccc(NC(=O)NC(C)C(C)C)cc1 +CCOC(=O)Nc1nc2c(Cl)cccc2s1 +COc1ccc(CN(C)C(=O)COc2ccccc2F)c(OC)c1 +CCCCN(C)C(=O)C1CCN(c2nccc(C)n2)CC1 +Nc1onc(CN2CCc3ccccc3C2)c1-c1ccccc1 +Cc1cc(C)cc(C(=O)N2CCN(CCn3nc(C)cc3C)CC2)c1 +O=C(CCCN1C(=O)CCc2ccccc21)N1CCN(CCO)CC1 +CCc1cccc(NC(=O)NCc2ncn(C)n2)c1 +Cc1cc(C)c(NC(=O)c2cccc(Oc3cnccn3)c2)c(C)c1 +COc1ccc(C)cc1C(=O)N1CCCN(S(C)(=O)=O)CC1 +O=C(CNC(=O)c1ccc(Cl)cc1)OC1CCOC1=O +Cc1nc(Nc2ccc(C#N)cc2)[nH]c(=O)c1CCO +CCc1nc(CCNC(=O)NC2CCC(O)CC2)cs1 +CCS(=O)(=O)NCCNC(=O)c1cc2ccccc2cc1O +COCC(C)N1CCN(C(=O)c2cncc(Br)c2)CC1 +Cc1csc2ncc(C(=O)NCCSc3ccccc3)c(=O)n12 +CCn1cc(S(=O)(=O)N(C)c2ccc(OC)nc2)cn1 +O=C(NC1CCSc2ccccc21)c1n[nH]c2ccccc12 +CC1c2cccn2CCN1C(=O)CNC(=O)C1CC1 +C=CCOc1cccc(NC(=O)c2cccc(-n3cnnn3)c2)c1 +O=C1CCS(=O)(=O)N1CCCOc1ccc2c(c1)CCC2 +CCn1c(=O)[nH]c2cc(-c3noc(-c4ccccn4)n3)ccc21 +NC(=O)C(OC(=O)Cc1cnn(-c2ccccc2)c1)c1ccccc1 +CN(Cc1ccc(-n2cccn2)cc1)C(=O)C1Cc2ccccc2O1 +CC(NC(=O)c1ccccc1)n1nc2ccccc2n1 +O=C(Nc1ccc(C(=O)NC2CCCCC2)cc1)c1ccnnc1 +O=C(NC1CCc2c(Cl)cccc21)c1n[nH]c(=O)[nH]1 +CC(=O)Oc1ccc(C(=O)Nc2ccc(CC#N)cc2)cc1 +O=C1N(CC2CC2)c2ccccc2C12CCN(Cc1ccco1)C2 +CCOCC1(CNC(=O)c2cnc(-c3ccccc3)[nH]c2=O)CCC1 +CCNC(=O)c1ccc(NC(=O)N(C)CC2CC2)c(C)c1 +CN(C)C(=O)C(C)(C)NS(=O)(=O)N1CCC(C(C)(C)C)CC1 +CN1CCN(C(=O)c2c(-c3ccncc3)cnnc2N)CC1 +CC(=O)NCCC(=O)NCc1noc(-c2ccco2)n1 +CCCCCn1c(C2CC(=O)N(C)C2)nc2ccccc21 +CC(C)Cc1cc(-c2nc(-c3ccncc3)no2)on1 +Cc1cc(F)ccc1CCNC(=O)NCCCc1c(C)noc1C +O=C(c1ccc(Oc2ccccc2)nc1)N1CCN(CCO)CC1 +CS(=O)(=O)Nc1ccccc1Oc1ccccc1 +CC(=O)Nc1ccc(S(=O)(=O)NC2CCCCC2O)cc1 +O=C1CC(C(=O)NCc2ccnc(OC3CCC3)c2)CCN1 +COC(=O)c1cnc(NC(=O)c2ccc3ccccc3n2)s1 +CCC(C)(C)NC(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +COc1ccc2c(c1)CCc1c(C(=O)N3CCC(C)CC3)noc1-2 +Cn1cnnc1SCc1nc(-c2cccs2)no1 +O=C(COCc1cc(-c2cccs2)on1)Nc1cccc(O)c1 +O=C(OCCNc1cccnn1)c1sccc1Br +CC(C)OCCCNc1ncnc2c1[nH]c1ccc(Cl)cc12 +CSc1ccc(NC(=O)N(C)Cc2ccoc2C)cc1 +CC(C)(C)C1CCC(C(=O)NCCCS(N)(=O)=O)CC1 +COc1ccc(CNC(=O)C2Cc3ccccc3N2C(C)=O)cc1 +Cc1c(CCC(=O)N(c2ccc(F)cc2Cl)C(C)C)cnn1C +CC(C)(C)NC(=O)CNC(=O)c1ccc(F)c(F)c1 +Cc1ccn2cc(C(=O)OC3CCC(C)CC3)nc2c1 +CCn1nnc2cc(C(=O)N(CCOC)Cc3ccccc3)ccc21 +O=C(CSc1ccc2c(c1)CCC2)NC1c2ccccc2CC1O +CCOCC1CC2(COCCN2C(=O)c2ccc(C)c(C)c2)CO1 +CC(C(=O)Nc1n[nH]c(Cc2cccc(F)c2)n1)c1cccnc1 +Cn1ccc2cc(C(=O)NCCCc3nc4ccccc4[nH]3)ccc21 +COCCN(C)C(=O)Nc1ccc2c(c1)OCCO2 +COc1ccnc(NCc2cnn(Cc3ccccc3)c2)n1 +COC(=O)C1=C(C)NC(=O)NC1c1ccccc1C +COc1cc(NC(=O)N(C)C(C)C2(C)CC2)ncn1 +Clc1cccc(Cl)c1CNCCc1ccccn1 +O=C(Cc1cccs1)Nc1cccc(C(=O)Nc2nccs2)c1 +CCOC(=O)N1CCN(C(=O)Nc2ccnn2C(C)C)CC1 +CCOc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1OCC +N#Cc1ccc(N2CCn3c(C(=O)N4CCCC4)cnc3C2)nc1 +Cc1cc(N)nc(SCC(=O)Nc2cc(C)nn2C(C)(C)C)n1 +NC(=O)c1ccc(Oc2cccc(Br)c2)cc1 +NC(=O)C1CCN(c2ccc(Br)cc2N)CC1 +CC(Cn1cccn1)NC(=O)C1Cc2cc(Cl)ccc2O1 +O=C(c1ccc(F)cc1O)N1CCC(OCc2ccc(F)cc2)CC1 +COc1cc(OC)c(C(N)c2cccn(C)c2=O)c(OC)c1 +COC(=O)Nc1cccc(NC(=O)N2CCCC(C)C2)c1 +Cc1ccccc1-n1nc(C)c(CN(C)Cc2ccc(C#N)o2)c1C +CCOCC(=O)Nc1c(C(=O)N2CCC(C)CC2)oc2ccccc12 +COc1ccc(CCNC(=O)N2CCC(CC(N)=O)CC2)cc1 +CC(C)c1nc(CNc2ccc(C(N)=O)c(F)c2)no1 +CC(=O)N1CCN(c2nnc(SCC#N)s2)CC1 +COC(=O)c1c(C)nc(C)c2c(=O)oc3c(OC)cccc3c12 +CC1=NC2(CCC3CN(S(=O)(=O)c4ccccc4)CC32)C(=O)N1C +CC(=O)N1CCC(NC(=O)NCC(C)Cn2nc(C)cc2C)CC1 +Cc1noc(-c2cc(Br)ccc2Cl)n1 +O=C(c1ccc(-n2cccc2)c(F)c1)N1CCCC1Cn1cccn1 +Cc1ccc(-c2nc(CCNC(=O)c3cc(C4CC4)[nH]n3)co2)cc1 +COc1ccc(NC(=O)CSc2ncn(-c3ccccc3)n2)cc1 +Cc1ccc(CNC(=O)NCC(=O)Nc2ccccc2F)cc1 +CN(C)C(=O)c1cccc(NC(=O)COc2cccc3ccccc23)c1 +CCCNC(=O)CCNC(=O)Nc1ccc(CC)cc1 +Cc1cccc(C(C)C)c1NC(=O)C(C)NC(=O)c1ccccc1 +CC(=O)c1ccc(NC(=O)NCCC2CCC2)cc1C +O=C(NCC1CC1)c1cc(-c2ccc(F)cc2)ns1 +CCC(C)n1ncc(C(=O)Nc2nc(C(C)C)nn2C)c1C1CC1 +CC(C)NS(=O)(=O)C1CCN(c2noc(-c3ccccc3)n2)C1 +COCCCNC(=O)c1ccc(-c2ccc3ccccc3c2)[nH]c1=O +Cc1cc(C)n2nc(C(=O)NCCC(=O)Nc3cccnc3)nc2n1 +Cn1cccc1C1CCCCCN1C(=O)c1ccsc1 +COc1ccc(-n2cnnc2SCC(=O)NCc2ccco2)cc1 +Cc1nccc(C2CCN(S(=O)(=O)c3cccnc3)CC2)n1 +O=C(NCC1CC1)c1ccc(NC(=O)c2cccs2)cc1 +Cc1cc(C)n(C(C)C(=O)Nc2ccnn2-c2cccc(Cl)c2)n1 +Cc1ccc(NC(=O)COc2ccc3c(c2)CCC(=O)N3)c(O)c1 +COc1ccc(-c2cc3n(n2)CCCN(C(=O)C2CCCO2)C3)cc1 +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)CN1CCOC(C)(C)C1 +Cc1ccc(C(=O)NC2CCN(c3snc4ccccc34)CC2)o1 +CC(C)OC(=O)C(C)n1nc(C#N)cc1-c1ccco1 +CCN(CC)C(=O)c1cn2cc(Br)ccc2n1 +CCN(C)c1cccc(NC(=O)N2CCCN(CC(F)F)CC2)c1 +CC(c1ccc(F)cc1)N(C)S(=O)(=O)Cc1ccccc1 +O=C(NCCc1ccc2c(c1)OCO2)c1cnccn1 +Cc1ccc(S(=O)(=O)N2CCC(C)CC2C)s1 +CCCN(CCC)C(=O)c1cc(-c2ccccc2)n[nH]1 +CN(CCN1CCCC1=O)c1ccnc(Cc2ccccc2)n1 +CC(=O)NCCC(=O)Nc1ccc2c(c1)OC1(CCCCC1)O2 +CCOCCOC(C)C(=O)N1CCc2ccccc2C1CC +C=CCN(CC=C)C(=O)c1cc(F)c(F)cc1Cl +O=C(CNC(=O)c1cscn1)Nc1ccc(-n2cccn2)cc1 +CN(C(=O)COc1cccc(C#N)c1)C1CCCc2ccccc21 +CCc1ccc(NC(=O)c2cc(F)ccc2C)cc1S(N)(=O)=O +Cc1noc(CN(C)C(=O)c2cc(C(C)C)no2)n1 +Cc1noc(C)c1S(=O)(=O)N1CCCCC1CCn1cccn1 +Cc1cc(C)c(CNC(=O)CCc2cnn(C)c2)c(=O)[nH]1 +COCCN(CC(C)C)C(=O)c1cnn(-c2ccncc2)c1C +c1cncc(CN2CCN(Cc3nc4ccccc4[nH]3)CC2)c1 +O=S1(=O)COCCN1Cc1ccc(OC(F)(F)F)cc1 +O=C1NCC2CN(c3nc(C(F)F)nc4ccccc34)CCN2C1=O +CCOC(=O)c1ccc(NC(=O)CSc2ncccn2)cc1 +Cc1ccc(N2CCCC(c3nc4ccccc4[nH]3)C2)nn1 +CC(c1ncnn1CCc1ccccc1)n1cc(Cl)cn1 +CC(C)(C)c1csc(C2CN(C3CCOC3=O)CCO2)n1 +CCN(Cc1cccc(N)c1)C(=O)C1COCCO1 +O=C(c1cc(F)ccc1F)N1CC2CCC(C1)N(CC1CCC1)C2=O +COc1ccnc(NC(=O)CC(c2ccccc2)C(F)(F)F)c1 +C=C(C)Cn1c(N2CCCC2)nc2c1c(=O)n(C)c(=O)n2C +CCOc1ccccc1C(=O)Nc1ccc(CS(=O)(=O)NC)cc1 +COC(=O)c1ccccc1OCC(=O)NCc1ccccc1C +CC(C)COCCC(=O)Nc1c(-c2ccc(F)cc2)ncn1C +CC(Sc1nnnn1C)c1ccccc1Cl +O=C(NCCNC(=O)C1CC1)c1sccc1C1CC1 +COC(=O)c1ccc(C(=O)OC)c(NC(=O)c2ccc(N)cc2)c1 +CCN(CC)C(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 +CCOc1cc(C(=O)Nc2ncc(C)s2)cc2occc12 +Cc1cnn(CC2CN(Cc3ccc(C(N)=O)cc3)CCO2)c1 +CC(NC(=O)c1cc2ccccc2n1C)c1ccc2c(c1)CCC(=O)N2 +COc1cc(OC)c(NC(=O)c2cccnc2)cc1Br +CN(C)S(=O)(=O)c1ccc(OC(=O)C2CC3CCC2C3)cc1 +COc1ccnc(NC(=O)CCCNC(=O)c2cccs2)c1 +COCCn1nc(C(=O)N2CCN(c3cnccn3)CC2)ccc1=O +Cc1ccc(NC2C(=O)Nc3cc(F)ccc32)c(C)c1 +CCN(CC)C(=O)Nc1nnc(CCC(=O)OC)s1 +C#CCNC(=O)NCCc1cccc(Cl)c1Cl +CC(=O)C(C)CSc1nnc(C(F)(F)F)n1N +O=C(Cc1csc(N2CCCC2=O)n1)OCC(F)(F)F +COc1ccc(CN2CC3=C(C2=O)C(c2ccccc2)NC(=O)N3)cc1 +CCOc1cc2c(cc1CSc1nnnn1C)OC(C)C2 +CCC1CN(C(=O)NCCNc2ncccn2)CCO1 +CCc1ncc(NC(=O)NCc2ncn(C)n2)cn1 +Cc1ocnc1CNC(=O)Nc1ccc(CC(F)(F)F)cc1 +C=C(C)CN(CC)C(=O)c1cccc(CSc2nccn2C)c1 +CCOc1ccc(NC(=O)C2CCN(c3ccccc3)C2=O)cc1 +CCc1nc(CNC(=O)c2cc3c(OC)cc(OC)cc3[nH]2)no1 +CCc1ccccc1NC(=O)CN(C)C(=O)Cn1cnnn1 +COc1cccc(C2CCN2C(=O)c2cnn3c(C)cc(C)nc23)c1 +CCCc1cc(C(=O)OC)c(NC(=O)CC#N)s1 +Cn1cc2c3c(cccc31)CN(C(=O)NCc1ccco1)CC2 +CS(=O)(=O)NC1CCCN(CC(=O)c2c[nH]c3ccccc23)C1 +CCC(CC)NC(=O)CNc1ccc(F)c(C(N)=O)c1 +CCC(=O)NC1CCCN(C(=O)Nc2ccc3c(c2)OC(C)(C)O3)C1 +Cc1cnc(C)c(N2CCC3(CN(C)C(=O)O3)C2)n1 +O=C1CN(C(=O)CCc2cccc(Cl)c2)CCN1 +CN(C)C(=O)c1cccc(NCC(=O)NC2(C#N)CCCCC2)c1 +CC(=O)Nc1ccc(C(=O)C(C)OC(=O)c2ccc(C)c(O)c2)cc1 +O=C(NCC(O)c1ccc(C(F)(F)F)cc1)Nc1cccs1 +Cc1ccc(OCc2nc(C)c(C(C)(C)O)s2)cc1 +CC(C)CC(=O)NCc1ccc(NC(=O)C2CC2)cc1 +O=C(CC1CCCO1)Nc1cnn(-c2ccccc2Cl)c1 +CC(C)CCN(CCC#N)Cc1cc(=O)c(O)co1 +CCc1noc2ncnc(N3CCc4ccccc43)c12 +CC(NC(=O)c1cc(-c2ccccc2)[nH]n1)c1ccccc1F +CN(CC(=O)Nc1cc(C(C)(C)C)n[nH]1)C(=O)c1cccs1 +Cc1cccc(C)c1NC(=O)CCCn1cnc2c(C)cccc2c1=O +CC(C)(CNC(=O)NCC1CN2CCCCC2CO1)c1ccccc1 +CCOC(=O)c1csc(NC(=O)c2cccc(N(C)C)c2)n1 +CCc1cc(NC2CC(=O)N(C3Cc4ccccc4C3)C2)ncn1 +Cc1ccc(S(=O)(=O)Oc2cccc(C#N)c2)cc1 +COc1cccc(C2CN(Cc3ccc(C#N)o3)CCO2)c1 +CCNC(=O)c1ccc(Cl)cc1NCC(=O)Nc1cccc(F)c1 +COCCNc1nc(Cc2ccccc2OC)no1 +CC(C)(C)CCC(=O)NC1CCN(c2ccccc2)C1=O +O=C(NC1CCCC1)c1c(Br)cnn1C1CC1 +O=C(NCC12CC3CC(CC(Cl)(C3)C1)C2)C1CCCO1 +Nc1ccc2c(c1)oc(=O)n2Cc1ccc(Cl)cc1Cl +CC(=O)Nc1nc(CN2CCOC(c3nc(C)cs3)C2)cs1 +CCCc1c(C(=O)N2CCN(CCO)CC2)[nH]c(C)c1C(=O)OC +O=S(=O)(NC1CCCc2occc21)N1CCCC1 +Cn1ccc(C(=O)Nc2cnn(Cc3cccc4ccccc34)c2)n1 +Cc1nc2nc(-c3cccs3)nn2c(C)c1CC(=O)NCCO +CCn1nccc1CNS(=O)(=O)c1cc(Cl)ccc1Cl +CCOc1nnc(CN2CC(n3cc(C)cn3)C2)s1 +Cc1cccc2nc(CSc3nccn3C3CC3)cn12 +CC(C)CCNC(=O)c1nc(-c2ccc(N3CCCC3)cc2)no1 +COC(=O)c1ccc(-c2nc[nH]c2-c2cccs2)cc1 +COc1cccc(C(C#N)CC(=O)NCc2ccc(C)cc2)c1 +O=C(NC1CCC2(CC1)OCCO2)c1ccc2[nH]cnc2c1 +Cc1cc(C)cc(NC(=O)C(O)c2ccc(F)c(C)c2)c1 +CC1(C)CCN(C(=O)c2scnc2C2CC2)C1 +COc1ccc(OCC(=O)Nc2ccccc2F)cc1 +NC(=O)C1CCN(C(=O)NCCc2ccccc2Cl)CC1 +COc1cccc(C(=O)NCC(=O)N(C)Cc2ccc(C)s2)c1 +CC(=O)Nc1cccc(OCC#CCNC(=O)C(C)(C)C)c1 +CC(C)(C)CC(=O)NCC1Cn2ccnc2CO1 +COCCN(CC(F)(F)F)C(=O)c1ccc(N2CCCC2=O)cc1 +COCc1cc(=O)[nH]c2cc(NC(=O)c3cc(C)on3)ccc12 +CC(O)CN1CCN(CC(=O)NCC2(c3ccccc3)CC2)CC1C +C=CCNC(=O)C(C)Sc1nccn1-c1ccc(C)cc1C +NC(=O)C1CCN(C(=O)c2ccc(Oc3ccc(Cl)cn3)cc2)C1 +CCN(C(=O)c1ccnc(C)n1)C(Cc1ccc(C)cc1)C1CC1 +CCn1nnnc1NC(=O)c1cc(Cl)c(OC)c(Cl)c1 +CC(CC(=O)NCC1CN2CCCCC2CO1)c1ccccc1 +O=C(c1ccc[nH]1)N1CCC(C(O)CCc2ccccc2)CC1 +NC(=O)CSc1ccccc1NCc1ccc(F)c(F)c1 +CN(Cc1nccs1)C(c1ccc(Cl)cc1)c1ncccn1 +Cc1ccc(Oc2cccc(C(=O)Nc3cccnc3)c2)nn1 +CC(C)n1cc(Br)cc1C(=O)OCc1cnn(C)c1 +CC(C)c1ccc(C#N)c(=O)n1CC(=O)Nc1ccccc1 +Cc1noc(C)c1N(C)C(=O)C1COc2ccc(F)cc2C1 +CCn1cc(-c2n[nH]c(=O)n2-c2ccc3c(c2)OCO3)c(C)n1 +O=S(=O)(NCCN1CCOCC1)c1cnn(-c2ccccc2)c1 +C#CCCCOC(=O)C1CCN(c2ccc(Cl)cn2)CC1 +CCNC(=O)N1CCN(C(C)C(=O)NCC(C)c2ccccc2)CC1 +COC(=O)CCCn1ccc2cc(Cl)ccc21 +CC(=O)c1ccc2c(c1)N(CC(=O)OCCC(C)C)C(=O)CO2 +O=C(Cc1cccs1)Nc1cccc(F)c1F +COC(=O)c1ccccc1-n1nc(C(N)=O)c2c1CCN(C)C2 +Cc1ccc(C(=O)NCc2ccc(CN3CCCC3=O)cc2)c(=O)[nH]1 +CC(NC(=O)c1nn(C)c2ccccc2c1=O)c1ccccc1 +Cc1nnc(-c2[nH]c(C)c(S(=O)(=O)NCc3ccco3)c2C)o1 +CC1(C(=O)NCCc2cccc(Cl)c2)Oc2ccccc2NC1=O +COc1ccc(C)cc1NC(=O)COc1ccccc1 +CCC(=O)Nc1cccc(NC(=O)c2cccnc2)c1 +COc1ccc(Cl)cc1CNc1nccs1 +CC1CN(C(=O)c2ccnc(OC3CCC3)c2)C(C)CO1 +CC(C)C(=O)c1ccc(SCC(=O)N2CCOCC2)cc1 +CN(Cc1c(F)cccc1Cl)C(=O)Cn1ccnc1 +Cn1c(=O)c2[nH]c(NCCO)nc2n(C2CCCCC2)c1=O +O=C(Cn1cncn1)Nc1cccc(Br)c1 +O=C(NCCc1ccccn1)c1cc2cc(-c3ccccc3)ccn2n1 +O=C(Cn1nnc2ccccc2c1=O)Nc1ccc(Cl)cc1 +CNC(=O)C1CCN(S(=O)(=O)c2cc(C)ccc2C)CC1 +COc1cc(C)c(-c2cc(NC3CC3)ncn2)cc1OC +CN(C(=O)CSc1ccc(Br)cc1N)C1CC1 +CC(=O)c1cccc(OCc2cc(C(=O)NCC(C)O)n[nH]2)c1 +C=CCNC(=O)CN1C(=O)COc2ccc(C(=O)N(C)C)cc21 +CCOc1ccccc1C(=O)N1CCc2cc(OC)c(OC)cc2C1 +Brc1cnn(Cc2noc(-c3ccsc3)n2)c1 +O=C1CC(c2ccc(O)cc2O)Oc2cc(O)cc(O)c21 +O=C(NCCNc1nc2ccccc2s1)c1ccc2ccccc2n1 +CN(C)c1cccc(C(=O)NC2CCc3c(O)cccc32)c1 +COCC12CCOC1CCN(S(=O)(=O)c1ccccc1Cl)C2 +Cc1ccc(-c2noc(-c3ccccc3OCC(N)=O)n2)cc1 +CCN(CC)S(=O)(=O)c1ccc(N2CCCC2)c(N)c1 +CCOc1ccccc1OCc1nc(CC)c(C(C)=O)s1 +CCOC(=O)CCC(C)NC(=O)c1ccc2cc[nH]c2c1 +CCOC(=O)c1c(C)noc1-c1cc(OC)cc(OC)c1 +Cc1ccc(CN(C)c2cc(C)nc3ncnn23)cc1 +CS(=O)(=O)N(CC(=O)N1CCOCC1)c1ccc(Cl)cc1 +CN(C)C(=O)COc1cccc(CNC(=O)CC2CC3CCC2C3)c1 +O=C(Nc1cccnc1)c1ccc(S(=O)(=O)N2CCOCC2)o1 +CNS(=O)(=O)c1cccc(CNc2nccn3cnnc23)c1 +Cc1ccc(C)c(NC(=O)COC(=O)CCn2c(C)csc2=O)c1 +Cc1nc(C)c(CC(=O)Nc2ccc3c(c2)OCO3)c(=O)[nH]1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)NCC(C)(C)C(N)=O +O=C(CCOc1ccc(C=Cc2ccncc2)cc1)N1CCNCC1 +Cc1cccc(CC(C)n2cnc3cccc(C)c3c2=O)n1 +Cc1nc(CNC(=O)c2cnc(-c3ccccc3)nc2)n[nH]1 +O=C(Cc1ccccc1Cl)Nc1ccc(N2CCCC2=O)cc1 +COC(=O)c1ncn(CC(=O)Nc2ccccc2)n1 +CC(CO)NS(=O)(=O)c1ccccc1C(C)(C)C +CN(Cc1ccco1)C(=O)Nc1cccc(C(=O)NC2CC2)c1 +Cc1cccc(C(C)CNC(=O)c2c(C)c(C)nn(C)c2=O)c1 +CC(C)CCC(=O)Nc1ccccc1N1CCOCC1 +C#CCNc1cc(Cl)ccc1C(=O)NCCC +COc1cc(NC(C)C(=O)N2CCOCC2)ccc1N1CCCC1=O +CC(C)(C)c1nnnn1CC(=O)NCC1(c2ccccc2)CCC1 +Cc1cccc(C2CC2C(=O)N2CCCC2Cn2cccn2)c1 +Cn1c(=O)n(C)c2cc(NS(=O)(=O)Cc3ccccc3)ccc21 +N#Cc1ncn(CC(=O)Nc2ccc(CN3CCOCC3)cc2)n1 +CC(C)CCC(=O)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +COc1ccc(F)cc1NC(=O)c1ncoc1-c1cccs1 +COc1ccc(C(=O)N(CC2CC2)C(C)C)c(O)c1 +CCc1noc(-c2ccc(OCC(=O)Nc3ccccc3)cc2)n1 +CCN(CCC(=O)NCc1ccc(F)cc1)C(=O)c1cnccn1 +CCC(=O)N1CCCCC1C(=O)Nc1ccc(F)cc1Cl +COc1cc(C)ccc1OCCC(=O)NCc1n[nH]c(=O)[nH]1 +C=CCn1c(C)nc2c(sc3nc4ccccc4n32)c1=O +COC(=O)c1ccccc1Nc1nc(C)nc2onc(C)c12 +CC(C)c1cnc(-c2ccc(NC(=O)NCc3ccnn3C)cc2)o1 +CCOc1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)c(C)c1 +COc1ccccc1C(=O)N1CCN(C(C)=O)C(C(N)=O)C1 +Cc1n[nH]c(C)c1NC(=O)c1ccc(OCC(F)F)nc1 +Cc1nnc(NCCCNC(=O)c2ccccc2F)c(C#N)c1C +Cc1cc(F)ccc1CCNC(=O)c1cc2ccccc2oc1=O +COC(=O)CNC(=O)C1CC1c1cccc2ccccc12 +CCN(CC)C(=O)CCC(=O)NC1CCCN(c2ccccc2)C1=O +CCOC(=O)Nc1nnc(SCc2cnc(C)cn2)s1 +COc1ccccc1OCC(=O)Nc1ccc(F)c(NC(C)=O)c1 +O=C1c2ccccc2C(O)(Cc2ccccc2)N1Cc1cccnc1 +Cn1cnc2cc(C(O)CNCc3ccncc3)ccc21 +OC1CN(c2nc3ccccc3s2)CC1N1CCOCC1 +CC(C)(C)c1ccc(OCCC(=O)N2CCNCC2)cc1 +CCCCN(C)S(=O)(=O)Nc1cccc(C(F)(F)F)c1 +COC(=O)c1ccccc1Cn1cnn(C(C)(C)C)c1=O +Cc1cnn(C2CCCN(C(=O)c3cnc(C4CC4)s3)C2)c1 +COCCNC(=O)C1C2CCC(C2)N1C(=O)c1ccccc1 +COc1ccc(NC(=O)C(C)Oc2ccc(F)cc2)cn1 +CC(C)COc1ccccc1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(NC1CCCCC1)C1CCCN1C(=O)c1ccnc2c1OCO2 +CC(O)C(=O)N1CCN(c2ccccc2-c2ccccc2)C(=O)C1 +CC(C)C1C(=O)NCCN1C(=O)c1ccc(O)c(Cl)c1 +COCCN1CCCn2c(nc(CNC(=O)COC)cc2=O)C1 +Cn1ccc(C2CCCCN2C(=O)c2cc(-c3cccn3C)n[nH]2)n1 +Cc1cnc2c(c1)nc(C(Cl)(Cl)Cl)n2CC#N +CCOCc1ccc(CNC(=O)NCC2CC2C)cc1 +Cc1noc(C2CCCN(C(=O)CCCN3CCOC3=O)C2)n1 +O=S(=O)(c1cccs1)N1CCc2ccccc2C1 +Cn1c(SCCNC(=O)OC(C)(C)C)nnc1-c1cccnc1 +Cc1cc2ncc(CNCc3ccc(-n4cncn4)nc3)cn2n1 +COc1ccc2c(=O)n(CCCn3cnnn3)ccc2c1OC +COc1ccnc(N2CCN(C(=O)Cc3ccc(C)s3)CC2)n1 +CCCc1c(C#N)c(N)nc(SCC(=O)c2ccccc2)c1C#N +O=C(NCc1ccccn1)c1c2c(nc3ccccc13)CCC2 +COc1ccc(OC)c(CC(C#N)C(=O)NC2CC2)c1 +Cc1ccc(NC(=O)COc2ccc(C(=O)NCCO)cc2)cc1F +COc1ccccc1-n1c(=O)n(C(C)C)c(=O)c2c1ncn2C(C)C +Cc1ccc(CCC(=O)OCC2CC(=O)N(C3CC3)C2)cc1 +Cc1cccc(C(=O)NCCOC2CCCC2)c1O +Nc1nc2nc(-c3ccco3)cc(C(F)(F)F)c2c(=O)[nH]1 +Cc1noc(C)c1CCC(=O)NC1CCOC(C)(C)C1 +COc1ccc(O)c(C(=O)Nc2cccc(-c3n[nH]c(C)n3)c2)c1 +N#CCCCOc1cccnc1NC(=O)Cc1c(F)cccc1F +CN(Cc1ccccn1)C(=O)NC1CC2CCC1(C)C2(C)C +CC(C)N(C(=O)c1csc(-c2cccs2)n1)C1CCOCC1 +CCn1nnnc1SC(C)C(=O)Nc1cc(C)ccc1OC +CCC(C)C(NC(=O)c1cccc(C(F)(F)F)c1)C(N)=O +Cc1cc2nc(C)c(CCC(=O)NCc3cscn3)c(C)n2n1 +CNC(=O)c1ccsc1NC(=O)c1ccc(C)cc1 +Cc1cc(C)c(C(=O)N(C)CC(C)(CO)CO)[nH]1 +COC(=O)NC1(C(F)(F)F)Oc2ccc(Cl)cc2O1 +Cc1ccccc1CSc1nnc(-c2ccncc2)n1N +O=C(C(CNCc1cccnc1)c1ccccc1)N1CCOCC1 +COC(=O)c1cc(C)ccc1OC(=O)c1ccc(C)[nH]c1=O +Cc1n[nH]c2oc(N)c(-c3nc4ccccc4[nH]3)c12 +CCc1nnc(NC(=O)CCn2[nH]c(=O)ccc2=O)s1 +Cc1ccccc1NC(=O)COc1cccc2c1CCCC2O +CCOC1CC2(CCN(C(=O)Cc3ccccn3)CC2)C1 +COCCn1cc(NC(=O)Cc2ccc(F)c(F)c2)cn1 +CCNC(=O)Cn1cc(C#N)c(=O)c2cc(Br)ccc21 +O=C1CCCN1c1cc(C(F)(F)F)ccc1Cl +CC(C)n1nc(-c2ccccc2)cc1NC(=O)NCC1CCCO1 +COc1ccc(S(=O)(=O)NCC2COc3ccccc3O2)cc1 +CC(CC#N)N(C)C(=O)Nc1ccc(Oc2ccc(F)cc2F)nc1 +Cc1ccccc1NC(=O)C1CCN(c2cnccn2)CC1 +O=C(CSc1cccnn1)Nc1cc(N2CCCCC2)ncn1 +CN(C)C(=O)C1CCCN1c1cc(F)ccc1N +Cc1nc(NCCc2[nH]nc3c2CCCC3)c2nc(C)oc2n1 +O=C(Nc1ccccc1F)NC1CNc2ccccc2C1 +COc1ccccc1CN(C(=O)Nc1nncs1)C1CC1 +CC(=O)Nc1cccc(NC(=O)CNc2ccc(F)cc2)c1 +CC(CNC(=O)c1cncc(Br)c1)Oc1ccccc1 +CC(C)(C)c1nnc(NC(=O)Cn2c(=O)oc3ccccc32)s1 +O=C(c1ccc(Sc2ccccc2Cl)nn1)N1CCC(O)C1 +COc1ccccc1N1CCC(C(=O)N(C)Cc2ccccc2)C1=O +CC(C)(C)c1cc(OC2CC2)c[nH]c1=NS(C)(=O)=O +CS(=O)c1cnc2c(c1)CCC(c1ccc(Cl)c(Cl)c1)O2 +CCc1ccccc1NC(=O)Cc1nc2ccc(N)cc2o1 +CCn1ccnc1SCC(=O)c1[nH]c(C)c(C(C)=O)c1C +O=C(CCCn1cncn1)Nc1ccn(-c2ncccc2Cl)n1 +Cc1nccn1Cc1cccc(CNc2ccc(C(=O)N(C)C)cn2)c1 +Fc1ccc(NCc2n[nH]c(-c3cccnc3)n2)cc1 +Cc1ccn(CCN2CC(C)(c3ccccc3)CCC2=O)n1 +Cc1nn(-c2ccc(C(=O)NCc3cscn3)cc2)c(C)c1Cl +COc1ccc2c(n1)Sc1c([nH]c(N)nc1=O)N2 +CCn1nc(C)c(CNC(=O)Nc2ccc3c(c2)OCCCO3)c1C +COC(=O)CNS(=O)(=O)c1ccc(F)cc1Br +COc1ccc(CCNC(=O)NCC(C)(O)C2CC2)cc1 +CCCCC(=O)OCc1nnc(-c2cccc(C)c2)o1 +Cc1ccc2c(=O)c(C(=O)N3CCOCC3)c[nH]c2n1 +Cc1cccc(C(=O)N(C)Cc2nc3ccsc3c(=O)[nH]2)n1 +CCCCNC(=O)C(C)Sc1nnc(N)n1C +CC(C)N(C)C(=O)CNc1cccc2ccccc12 +CN(C(=O)C1CC1)c1ccccc1C(=O)Nc1cnc2ccccc2c1 +Cc1n[nH]cc1CN1CCOC(c2ccccc2Br)C1 +CCOc1ccccc1CNC(=O)Nc1nnc(C(F)(F)F)s1 +CC(=O)N1CCN2C(=O)N(C3CCCCC3)CC2C1 +Cc1sc(=O)n(CC(=O)NCc2ccnc(OC3CCC3)c2)c1C +COc1ccc(C2CC(=O)c3cn4nc(C)nc4nc3C2)cc1 +Cc1ccc(S(=O)Cc2cccc(Br)c2C)nc1 +Cc1nc2ncnn2c(C)c1CCC(=O)OCc1ccccn1 +COCc1ccccc1NC(=O)NCc1cccnc1OC +COC(=O)c1cc(NCc2nc(-c3ccco3)no2)c(F)cc1F +COc1cc(CCC(=O)N2CCCCC2)ccc1OCC(F)(F)F +CC1(C)C(=O)NCCN1CC1=Cc2cc(Cl)ccc2OC1 +NC(=O)CN1CCN(CCOc2cccc(Cl)c2)CC1 +Cn1ccc(C(=O)Oc2cccc(Cl)c2Cl)cc1=O +COCCC(C)NC(=O)NCC(O)c1ccc(Cl)cc1Cl +COCCNC(C)C(=O)c1ccc2c(c1)NCC(C)O2 +CCN(CC(C)C#N)C(=O)CCc1nc(C(C)C)no1 +CNC(=O)COC(=O)CSc1nccn1-c1ccccc1C +CC(Cc1ccsc1)NC(=O)CNC(=O)CC(C)(C)C +CSc1nc2cc(Cl)ccc2c(=O)n1Cc1ccco1 +CCOc1cc(F)ccc1NCC(=O)Nc1ccccc1 +CCCn1c(C)nnc1SCc1ccc(OC(C)=O)cc1 +NC(=O)c1cccc(S(=O)(=O)Oc2ccc3ccccc3c2)c1 +CC(NC(=O)NCCCOC1CCCCC1)c1nncn1C +CCOc1ccccc1NCc1cccc(C(=O)N2CCCCC2)c1 +CCCn1c(SCC(=O)Nc2sccc2C#N)n[nH]c1=O +CCNC(=O)N(CC)Cc1nc(-c2ccc(C)cc2)no1 +CCc1cc(C(=O)OC)c(NC(=O)CN2CC(C)OC(C)C2)s1 +CC1CCCCC1N(C)c1ncnc2c1cnn2C +O=C(Nc1cccc(CO)c1)C1(c2ccc(Cl)cc2)CC1 +Cc1ccc(-c2nc(CN3CCN(CCO)CC3)cs2)o1 +COCCn1c(C)cc(-c2cccc(OC)c2)c(C#N)c1=O +CCN1CCN(C(=O)C(C)Oc2ccc(C)cc2)CC1 +Cc1nn(C)c2ncc(NC(=O)COc3ccccc3)cc12 +COc1ccc(-c2n[nH]c(-c3ccc(Cl)c(N)c3)n2)cc1OC +CC(=O)OCC(=O)Nc1cc(Cl)ccc1C#N +COc1cc(C)c(-c2c(CCO)sc3nccn23)cc1C +Cc1ccc(CNC(=O)Nc2ccc(NC(=O)c3ccco3)cc2)cc1 +CCCNC(=O)c1nnn(-c2ccc(F)cc2)c1C +COc1ccc(-c2nc(CS(=O)(=O)c3ccc(F)cc3)no2)cc1 +O=C(c1ccc(N2CCN(CCO)CC2)nc1)N1CCOCC1 +Nc1cc(Cl)cc2c(CC(=O)N3CCCC3)noc12 +CC(NC(=O)C1CC=CC1)c1ccc(OCC(=O)NC2CC2)cc1 +CCOc1cc(C)c(C(C)C)cc1S(=O)(=O)N(C)C +Cc1cc(NC(=O)CN2CCN(c3ccccc3F)CC2)no1 +CCCNC(=O)c1ccc(-c2ccc(C(C)=O)cc2)o1 +Cc1ccc(CNc2ccc(C(N)=O)cc2N)s1 +CC(=O)c1cccc(S(=O)(=O)N(Cc2cccc(F)c2)C2CC2)c1 +CCCN1Cc2cccc(C(=O)NCc3ccc(Cl)cc3)c2C1=O +CCN(CC(=O)OC)C(=O)Cc1ccc(Cl)cc1Cl +O=C(Cn1ccc(C(F)(F)F)n1)N1CCN(C2CCCC2O)CC1 +COc1cc2c(cc1F)CCNC2c1cncc(F)c1 +COc1ccc(C)cc1C(=O)C1CCCN1C(=O)C(C)C +Cc1cc(NC(=O)CSc2ccc(-c3ccccc3)nn2)no1 +Cc1[nH]c2nc(NCc3ccc(Cl)cc3)nn2c(=O)c1CCO +NS(=O)(=O)c1ccc(CCNC(=O)Cc2cccc(F)c2)cc1 +C#CCOc1ccc(C(=O)Nc2cc(F)ccc2OC)cc1 +CC(C)(C)Oc1ccc(NC(=O)NCc2ncc[nH]2)cc1 +O=C(Nc1ccn(Cc2ccccn2)n1)c1ccccc1Cl +O=C(c1cccc(F)c1)N1CCC(Oc2cccnc2)CC1 +Cc1cccc(CC(=O)Nc2c3c(nn2C)CCC3)c1 +CC(C)NC(=O)c1cnn(-c2ccc(F)cc2)c1-n1cccc1 +CCC(=O)N1CCC2(CC1)CC(CC(=O)N(C)C)c1ccc(F)cc12 +C#CCN1CCN(C(=O)CN(CCc2ccccc2)C(C)=O)CC1 +COC(=O)c1ccc(C(=O)NCC(C)(C)c2ccncc2)s1 +CCC(=O)N1CCCN(C(=O)NCc2cccc(C)c2)CC1 +CCC(C)C(C(=O)N1CCN(C(=O)CO)CC1)c1ccccc1 +Cc1cc2c(cc1C(O)C1CCCCC1)n(C)c(=O)n2C +O=C(Nc1ccn(Cc2ccncc2)n1)N1CCOC2(CCCC2)C1 +N#CC1(C(=O)NCCC(=O)NC2CCCC2)CCCC1 +O=C(Nc1cccc(O)c1)c1cnn(Cc2ccccc2Cl)c1 +Cc1ccc(-c2c(-c3ccccc3)ncn2C(C)C(N)=O)c(F)c1 +COC(=O)CC1CCCCN1S(=O)(=O)c1ccccc1F +CCCc1cc(=O)oc2cc(Oc3ncnc4c3cnn4C)ccc12 +N#Cc1ccsc1C(=O)NCc1nc2ccccc2s1 +COCCNC(=O)CCNC(=O)Nc1cc(C)on1 +Cc1nnc(SCc2ccc(OC(F)F)cc2)s1 +CCSc1ccc(C(=O)N2CCCCC2CNC(N)=O)cn1 +Cc1cccnc1NC(=O)C1(c2cccs2)CCOCC1 +Nc1cc(S(=O)(=O)N2CCCCC2)cc2oc(=O)[nH]c12 +COc1ccc(NC(=O)c2cccc(OCC(F)F)n2)cc1C +COC(=O)C(C)CN(C)S(=O)(=O)N1CCC(C)CC1 +C=CCC1(OC)CCN(C(=O)c2cc(CN3CCOCC3)on2)CC1 +COc1cc(C#N)ccc1OC(=O)Cc1ccc(F)cc1 +CC(=O)Nc1cc(NC(=O)c2ccccc2Cl)ccc1Cl +COc1ccc(OC)c(S(=O)(=O)CCCO)c1 +C#CCNC(=O)C1CCN(C(=O)c2ccc(Br)cc2)CC1 +CCOc1ccccc1OS(=O)(=O)c1ccccc1F +CSc1ccsc1C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +CCc1nc(CC(=O)Nc2ccc(Oc3cc(C)[nH]n3)cc2)cs1 +O=C(CCSc1ccccn1)NC1CCN(c2ccccc2)C1=O +CCS(=O)(=O)NCC1Cn2nnc(-c3cccc(C)c3)c2CO1 +CC(C)n1nccc1NC(=O)CCc1nc2ccccc2s1 +CC(=O)Nc1ccc(F)c(NC(=O)C2CC(=O)N(C)C2)c1 +CNC(=O)c1cc2ccccc2cc1OCc1c(C)noc1C +CC(C)c1nnc(SCC(=O)c2cc3ccccc3oc2=O)o1 +COC1CCC(N(C)C(=O)CSc2ccc(C)cc2)CC1 +Cc1ccc(CNC(=O)NCCCO)c(N(C)C)c1 +O=C(c1sccc1-n1cccc1)N1CCN(c2ccccc2)CC1 +CC(C)(C)c1ccccc1S(=O)(=O)NC1CC2CCC1O2 +O=C1COc2ccc(NC(=O)c3ccc(F)cc3Cl)cc2N1 +COc1ccc(OCCN2CCOc3ccc(N)cc32)cc1 +C=CCN(Cc1nc(C)cs1)S(=O)(=O)c1ccc(OC)cc1 +COC(=O)COC(=O)Cc1coc2ccc3ccccc3c12 +CC(CNC(=O)N1CCCN(CC(F)F)CC1)c1cccs1 +CC(C)Nc1nnc(SCC(=O)NC(C)(C)C)s1 +CCc1nc(CC(=O)Nc2ccc(OC)c(C)c2)cs1 +CC(=O)Nc1ccc(NC(=O)Cc2ccccc2C)cc1C +COc1cccc(OCc2nc(C)c(CCO)s2)c1 +O=C(Nc1ccccc1N1CCc2sccc2C1)C1CCOCC1 +CC1CCN(C(=O)CCNC(=O)c2ccc(F)cc2Cl)C(C)C1 +COc1ccccc1OCC(=O)NCC1C(=O)N=C(C)C=C1C +Cc1cc(=O)oc2cc(Oc3ccc(C#N)cn3)ccc12 +CC(C)c1nnc(C2CCN(C(=O)c3c[nH]c4ccccc34)CC2)o1 +O=C(c1cccnc1-c1cncnc1)N1CC2CCC1C2 +COc1ccc(F)cc1C(=O)N(C(C)C)C1CCC1 +CCNC(=O)NC1(C(=O)NC2CCCc3occc32)CCCC1 +Cc1cc(C)n(-c2ccc3cccc(-n4cnnc4)c3n2)n1 +COc1ccc(C(=O)NCc2cccc(Cl)c2)cc1OC +CC(C)CC(=O)NCCC(=O)N1CCc2sccc2C1 +CCc1oc(-c2ccc3c(c2)OCCO3)cc1CO +CC(C)c1ccc(C(=O)CCCC(=O)NC2CC2)cc1 +COCc1ccccc1NS(=O)(=O)c1ccc(F)cc1 +CC(C)COc1ccc(CN(C)C(C)CC#N)cc1 +Cc1sc(C(=O)NCc2ccccc2)cc1S(=O)(=O)N(C)C +O=C(NCc1nc2ccccc2s1)c1ccc(OC(F)F)cc1 +CCC(C)NC(=O)NS(=O)(=O)c1ccc(C)cc1 +NC(=O)c1n[nH]c2ccc(NC(=O)Cc3ccc4ccccc4c3)cc12 +CC(=O)Nc1ccc(C(=O)N(C)c2cccc3ncccc23)cc1 +COCCNc1nc2ccc(OC(C)C)cc2s1 +COc1cc2c(cc1OC)CCN(C(=O)c1cc(C)n[nH]1)CC2 +CC(=O)Nc1ccc(-c2nn3c(C(F)(F)F)nnc3s2)cc1 +Nc1[nH]nc(-c2cccnc2)c1-c1cccc(F)c1 +Cc1cc(CN(C)C(=O)c2cc(C(C)C)nc3onc(C)c23)no1 +Cc1ccc(C(=O)N2CCCCC2CN2CCOCC2)c(C)n1 +CC(=O)Nc1cc2c(cc1C(=O)C(C)C)OCCO2 +Cc1cc(C)cc(NC(=O)C23CCC(C2)C(C)(C)C3=O)c1 +CCc1ncnc2c1CCN(C(=O)NC1CCCC1)CC2 +C#CCN(CC#C)Cc1cn(-c2ccccc2)nc1-c1ccncc1 +O=C(NC1CN(C2CCOC2)C2CCCOC12)c1ccno1 +Cc1cc(C(=O)N2CCCC2c2ccccc2)c(C)n1Cc1ccco1 +CCCCN1C(=O)c2cc(N)ccc2S1(=O)=O +O=C(CCc1nc(-c2cccnc2)no1)Nc1cccc2ccccc12 +COc1ccccc1-n1cnc2cc(NC(=O)c3ccco3)ccc21 +Cc1noc(CCCC(=O)N2CCCCC2C)n1 +CCc1[nH]c(C(=O)Nc2c3c(nn2C)CCC3)c(C)c1C(=O)OC +O=C(NCC1(O)CCCC1)c1cncc(Br)c1 +O=C(Nc1cnc2n1CCCC2)c1n[nH]c2c1CCC2 +CC(=O)Nc1nc2ccc(NC(=O)NC3CCCCC3)cc2s1 +COc1ccc(CC(=O)Nc2c(C)cnn2CC2CC2)c(OC)c1 +c1ccc(CCCNc2ccc(CN3CCOCC3)cc2)nc1 +CCCOc1ccc(CNC(=O)Nc2ccc3c(c2)OCCO3)cc1 +CC(=O)N1CCC(NC(=O)NCC(=O)NC2CC2)CC1 +CC(O)CNC(=O)c1cc(F)c(Cl)cc1Cl +C=CCOC(C)C(=O)Nc1nc(-c2ccco2)cs1 +CC12OC(C=C1CO)CC(=O)C2OCc1ccccc1 +Cc1cccc(NC(=O)C2CCC(=O)N2Cc2cccs2)n1 +Nc1nc(C(=O)N2CCCC(COc3cccc(F)c3)C2)n[nH]1 +Cc1cc(C(=O)Nc2ccc(N3CCOCC3)nc2)[nH]n1 +CCN(CCn1cccn1)C(=O)c1sc(C)nc1C +Cc1ccccc1C(=O)NC(C(=O)NCCc1cccs1)C(C)C +Cc1ccc(NCc2c(C)[nH]c3ccccc3c2=O)cc1C +COc1ccc(-c2[nH]nc(C)c2CC(=O)NCCc2ccco2)cc1 +COCCNC(=O)CNC(=O)c1c(F)cccc1Cl +COc1ccc(C(C)NC(C)C(=O)NCC(C)C)cc1F +Cc1nn2ccccc2c1C(=O)N(C)Cc1ccccc1 +Cc1cc(N)ccc1NC(=O)CCOCC1CCCCO1 +O=C(COc1cccc(C(F)(F)F)c1)NCC1CC1 +COCC(C)NC(=O)C(C)(C)Oc1ccc(Cl)cc1 +COC(=O)c1cc(CCNC(=O)OC(C)(C)C)ccc1F +COc1cc(C)ccc1OCC(=O)Nc1cnc2c(c1)c(C)nn2C +CN(C(=O)c1cnn(C)c1)C(c1ccccc1)c1ccc(F)cc1 +Cc1nc2nc(C(F)(F)F)nn2c(C)c1CC(=O)NCC1CCC1 +Cc1ccccc1C(=O)NC(C#N)c1ccccc1F +O=C(CCNc1ccccc1)NC(C1CC1)C1CC1 +O=C(NC1CCN(C(=O)c2ccccc2)CC1)c1cnc2cc[nH]c2c1 +COc1ccc(C(=O)N2CCC(Nc3ccccc3OC)CC2)nn1 +O=S(=O)(Cc1ccc(F)cc1)NCC1(O)CCOCC1 +COc1nc(C)c(C(=O)N(C)Cc2cccc(-n3cccn3)c2)s1 +CCOC(=O)N1CCC(n2ccc3nc(SC)ncc3c2=O)CC1 +CC(=O)Nc1sc(C)c(C)c1C(=O)OCc1cc(C)no1 +CN(CCC(F)(F)F)C(=O)CSc1ccccc1 +COc1ccc(-c2ncccc2C(=O)N2CCCC2)c(OC)c1 +COc1ccc2oc(=O)c(C(=O)Nc3ccc4cn[nH]c4c3)cc2c1 +CCOCCCNC(=O)c1onc(S(C)(=O)=O)c1N +CN(C)c1ccc(C(F)(F)F)cc1NC(=O)C1CC1 +O=C(CSc1nnc2ccc(-c3ccccn3)nn12)N1CCCC1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)c1ccc(-n2cncn2)nc1 +CC1CCCN(C(=O)c2cn(C)nc2C(C)(C)C)C1 +CC(C)CCC(C)(O)CNC(=O)Nc1ccc(C(N)=O)cc1 +O=C(Nc1ccc2c(c1)OCO2)NC1C2CCC(C2)C1CO +CCOCCNC(=O)N(C)C(C)c1ccc(F)c(F)c1 +Cc1ccccc1N1CCN(C(=O)C2Cc3ccccc3CN2)CC1=O +CC(=O)N(C)Cc1cccc(NC(=O)Nc2ccc(C)cc2)c1 +N#Cc1cccc(NC(=O)c2ccc(-n3cnc4ccccc43)cc2)c1 +Cc1cc(NC(=O)C(C)N2CCOC(Cn3cccn3)C2)no1 +Cc1cccc(C)c1OC1CN(C(=O)C(O)c2ccc(F)cc2)C1 +CC(C)(C#N)C(=O)NC1CCCN(S(C)(=O)=O)C1 +Cc1n[nH]cc1CN1CCOC(c2cccs2)C1 +CC1CCN(C(=O)c2ccccc2NCc2nc(C3CC3)no2)CC1 +Cc1nnc(CN2CCN(c3nc4ccccc4s3)CC2)o1 +O=C(c1cc[nH]n1)N(Cc1ccco1)Cc1ccco1 +CSc1ncnc(Nc2ccc(C)cc2)c1C#N +Cc1cccc(C(=O)NC2CNc3ccccc3C2)c1 +CC(=O)N1CCc2cc(S(=O)(=O)N3CCN(C)CC3)ccc21 +COc1ccc(-c2cc(CO)nn2CC(N)=O)c(C)c1 +N#Cc1cc(C=C2OC(=O)c3ccccc32)ccc1F +Cc1cnc(CCNC(=O)CC2CCCCC2)s1 +CCCNC(=O)c1c(NC(=O)c2ccco2)sc2c1CCCC2 +CNC(=O)C1CCCCN1C(=O)Cc1csc(-c2ccc(C)o2)n1 +O=C(COC(=O)c1cc2ccccc2oc1=O)c1ccccc1 +Nc1csnc1C(=O)Nc1cccc(C(F)(F)F)c1 +COC(=O)c1ccc(N(C)CC(F)(F)C(F)F)cc1 +CC(=O)N(C)c1cccc(NC(=O)N(C)CCOCC2CC2)c1 +CC(C(=O)Nc1ccc(Oc2cccnc2)nc1)c1cccnc1 +Cc1nccc(CNC(=O)c2ccccc2Br)n1 +O=C(Cc1noc(C2(c3ccccc3)CCC2)n1)NC1CCCC1 +O=C(NCC(=O)N1CCc2cc(F)ccc2C1)c1cccc(Cl)c1 +CCc1ccccc1NC(=O)c1cc(N)cnc1C +Cc1nc(CN(C)C(=O)Nc2ccc(C#N)cc2)cs1 +O=C(CC1CCCC1)NC1CCC(C(=O)Nc2ccncc2)CC1 +CCc1nc(C2CCCN(C(=O)c3ccsc3)C2)no1 +CC(C)(CNC(=O)c1sccc1Br)c1ccncc1 +COC(=O)c1cc(-c2ccc(Cl)cc2)n2c(N)nnc2n1 +O=C(Cc1csc(-n2cccc2)n1)Nc1ccc2c(c1)OCO2 +COc1ccc(NC(C)=O)cc1NCc1csnn1 +CC(=O)N1CCc2cc(CNC(=O)NCC(C)C)ccc21 +Nc1nccnc1C(=O)Nc1ncccc1OCC1CCCCC1 +COc1ccc(C(=O)NCc2ccsc2)cc1OC +O=c1c2c3c(sc2ncn1Cc1noc(C2CC2)n1)CCCC3 +Cc1ccc(S(C)(=O)=O)cc1C(=O)N1CCCC1C1CCCCC1 +O=C(c1cccc2ccnn12)N1CCCC1Cn1cccn1 +Cc1cc(C(=O)N2CC3COCC3(c3nnc(C(C)C)o3)C2)on1 +Cc1ccc2c(c1)NCC(=O)N2Cc1ccc(C#N)cc1 +CN(CC1CCOC1)c1ccnc(Cc2ccccc2)n1 +Cc1ccc(NC(=O)Cn2nc3cnc4ccccc4n3c2=O)cc1 +Cc1c2c(n3c(nc4ccccc43)c1C#N)N(Cc1ccccn1)CC2 +CC(COc1ccc(F)cc1F)NC(=O)c1cnn(C)c1 +CC(=O)NC(C(C)C)C1NCCc2c(N)cc(F)cc21 +O=S(=O)(c1cccnc1)N1CCN(c2ccc(F)cc2)CC1 +CC(C#N)CN(C)C(=O)C(C)Sc1nncn1C +O=C(NCC1CCCO1)c1ccc(CSc2ccccc2)o1 +CCOC(=O)Cc1csc(-c2ccc(O)cc2)n1 +CN1CCCN(C(=O)c2cccs2)c2nc3ccccc3nc21 +O=C(NCc1cccnc1OC1CCCC1)C1CC2CCC1C2 +COc1ccc(S(=O)(=O)NC2CCN(C(C)=O)CC2)cc1Cl +CNC(=O)c1cccc(OC(=O)COc2ccc(F)cc2)c1 +COc1ccc(NC(=O)C2CN(Cc3ccccc3)CCO2)cc1C +CC(C)COc1ccccc1NC(=O)N1CCC2(CC1)CC(O)CO2 +Cc1nn(-c2ccc(C(=O)NC3CCC(O)CC3)cc2)c(C)c1Cl +COc1cc[nH]c(=NS(=O)(=O)c2ccc(OC(F)(F)F)cc2)c1 +Cc1csc2ncc(C(=O)NCCc3cccs3)c(=O)n12 +COc1ccccc1CNC(=O)c1nn(-c2ccccc2)c(C)cc1=O +CN(Cc1ccccc1Cl)C(=O)c1cccc2[nH]ccc12 +COc1ccc(F)c(NC(=O)c2ccc(-n3cccn3)cc2)c1 +COC(=O)C1CCCN(CC2=Cc3ccccc3OC2)C1 +CCn1nnc2cc(C(=O)Nc3nc4c(s3)CC(C)CC4)ccc21 +COCCn1c(SCC(=O)NC(C)(C)C)nc2ccccc21 +CCCc1nc(CNc2ccc3oc(=O)n(C)c3c2)cs1 +CCC(C)(C)NC(=O)c1ccc(NC(=O)NCCOC)cc1 +CNC(=O)Nc1ccc(NC(=O)c2ccccc2SC(C)C)cc1 +CC(C)Cc1ncc2c(n1)CN(C(=O)CCN1CCCCCC1=O)C2 +Oc1cccc(CN2CCN(c3ccccc3F)CC2)c1 +Cn1nnc2c(SCC(=O)Nc3ccc(C(N)=O)cc3)ncnc21 +CC(C)(C)N1CC(C(=O)Nc2ccncc2)CC1=O +Cc1nc(-c2cc(-c3nc(-c4ccc(C#N)cn4)no3)co2)cs1 +Cc1nn(C)c(C)c1-c1ccc(=O)n(C(C)C(=O)NC(C)(C)C)n1 +CCc1c(C(=O)NCC(C)(C)c2ccncc2)cnn1-c1ccccn1 +CC(=O)c1cccc(NC(=O)c2coc(NC(=O)c3ccccc3)n2)c1 +CN(Cc1nc2ccccc2[nH]1)C(=O)CN1CCCCCC1=O +CCOC(=O)C(O)(c1cc(C)ccc1O)C(F)(F)F +CCN(CC)C(=O)CN1CCN(c2ccc3c(c2)OCO3)C1=O +CCOc1ccc(C(=O)Nc2nc(C3CC3)cs2)cc1OCC +Cc1nn(CC(=O)OCC2CC(=O)N(C3CC3)C2)c(C)c1Cl +CCCNC(=O)CNC(=O)c1cccc(N2CCCS2(=O)=O)c1 +Cc1cccc(C(=O)NC(C(=O)NCC(=O)NC(C)(C)C)C(C)C)c1 +NC(=O)N1CCN(C(=O)COc2ccccc2O)CC1 +CC(C)n1c(CNS(=O)(=O)c2ccccc2)nc2cccnc21 +CSc1ccc2nc(NCCN3CCOCC3)sc2c1 +O=S(=O)(NCc1ccccc1)c1cccc(C(F)(F)F)c1 +CCCOc1c(OC)ccc2c1CCNC2c1ccnnc1 +Cc1ccc(C(=O)NCC(C)C)cc1NS(C)(=O)=O +COC(=O)CNC(=O)CN1c2cccc3cccc(c23)S1(=O)=O +Cc1cccc(CC(=O)N=c2[nH]nc3cc(C)ccn23)c1 +O=C(c1cnccn1)N1CCN(C2CC2)CC1Cc1ccccc1 +Cc1ccccc1OC(=O)CCCNC(=O)c1ccco1 +O=C(Cc1ccsc1)N1CC2CCC(C1)N(CC1CCC1)C2=O +COc1ccc(NC(=O)c2ccc(F)cc2F)cc1S(N)(=O)=O +COc1ccc(C(C)N(C)C(=O)c2cc(OC)c(C)c(OC)c2)cc1 +CCNC(=O)CCNS(=O)(=O)c1cccc(C(C)=O)c1 +Cc1occc1C(=O)N(C)c1ccc(F)c(F)c1 +COc1c(O)ccc2c1C(c1ccccc1C)NCC2 +CC(C)c1ncncc1C(=O)NC1CCCc2[nH]c(=O)ccc21 +Cc1cc(C(=O)NCC(=O)NCC(C)Oc2ccccc2)c(C)o1 +O=C(CNC(=O)C1CCCCC1)NCc1nnc2n1CCCCC2 +COc1cccc(CNc2ncn[nH]2)c1OCc1ccccc1Cl +CN(CCc1ccncc1)S(=O)(=O)c1ccc(O)cc1 +COc1ccccc1C1CC(=O)NC(C)=C1C(=O)OC1CCCC1 +COCC(=O)NCC1Cc2cccc(-c3cccnc3)c2O1 +Nc1ccccc1OCC(=O)Nc1cccc(Br)c1 +CC1CCCCC1OCCSc1nncs1 +CCOC(=O)C1=C(C)N(C(C)C)C(=O)NC1c1ccc(C)o1 +Cc1nc(COc2cccc(C(=O)OCC3CCCO3)c2)cs1 +COc1cc(C)c(S(=O)(=O)N(C)CCCO)cc1C +COc1ccc2c(c1)OCC(C(=O)NCCCn1cncn1)C2 +Cc1cc(C(=O)N(C)Cc2cc(Cl)cc(Cl)c2)no1 +CC1CN(C(=O)c2ccc(-n3ccnn3)cc2)c2ccccc2O1 +COc1ccccc1-c1nc(C#N)c(N2CCOCC2)o1 +Cn1nc(C(=O)Nc2cccnc2)cc1NC(=O)c1cccs1 +CCN(CC)C(=O)CNC(=O)c1c[nH]c2ccccc2c1=O +CC(=O)Nc1c(Cl)cnn(-c2ccccc2)c1=O +COC(=O)c1ccc(C(=O)NCCC(O)c2cc(C)oc2C)cc1 +CC1CCCCC1NC(=O)COC(=O)c1ccc[nH]c1=O +O=C(Cn1cnc2ccccc2c1=O)NCC1CC2C=CC1C2 +COc1ccc(CCNC(=O)C2CCC(Cn3cnnn3)CC2)cc1 +Cc1c(CCC(=O)Nc2nc3ccc(F)cn3n2)cnn1C +CCOc1cccc(N2CCN(C(=O)NCc3ncn(C)n3)CC2)n1 +COCC(=O)NCCC(c1ccccc1)c1ccccc1 +O=c1[nH]c(-c2cccnc2)nc2sc3c(c12)CCC3 +CNC(=O)c1ccc(NC(=O)NCc2cccc(C(N)=O)c2)cc1 +CCN(CC)S(=O)(=O)c1cccc(NC(=O)CC2CCCC2)c1 +Cc1ccccc1C(=O)N1CCn2nnc(COc3cccnc3)c2C1 +CNc1snc(C)c1C(=O)N1CCN(c2ccccc2OC)CC1 +O=C(CCN1CCCC1=O)NC1CCCN(Cc2ccccc2)C1=O +COC(CNC(=O)NCc1ccc(F)cc1)c1cccc(F)c1 +Cc1csc(C(NC(=O)C(C)NC(=O)c2cccs2)C2CC2)n1 +Cc1nc(SCc2cc(=O)n3ccsc3n2)n(CC(C)C)c1C +OCC(O)C1NCCc2ccc(F)c(C(F)(F)F)c21 +O=C(Nc1ccc(CN2CCOC2=O)cc1)c1cccnc1 +COC(=O)CC(C)Nc1cccc(NC(C)=O)c1 +CCCCC1C(=O)N(C)CCN1C(=O)Nc1ccccc1SC +CCOC(=O)C1CCCN(C(=O)NCc2cccc(C)c2)C1 +Cc1c(COC(C)C)cccc1NC(=O)NC(C)C(C)CO +COc1ccc2c(c1)OCC(CNC(=O)CCn1cncn1)C2 +O=C(CCc1cccnc1)N1CCCC1CN1CCOCC1 +Cn1cccc(NC(=O)NCc2cccnc2OC2CCCC2)c1=O +Cc1cc(C)n2nc(SCc3ncc(C(C)C)o3)nc2n1 +N#CC(C(=O)Cc1ccc(N2CCCC2=O)cc1)c1ccccn1 +O=C(C1CC1)N1CCOC(c2cccc(OC(F)F)c2)C1 +O=C(NCC1CCOCC1)C1CCN(c2ncccn2)C1 +Cc1nn(C)cc1CN1CCN(Cc2nccn2C(F)F)CC1 +COc1ccc(F)c(NC(=O)c2ccc(OC)c(OC(F)F)c2)c1 +O=C1COc2ccc(Cl)cc2N1Cc1nc2ccccc2c(=O)[nH]1 +CCOC(=O)c1cnn(-c2ccc(CC)cc2)c1N +Cc1nc(CCc2ccc(O)cc2)sc1CCO +CCC(=O)Nc1cccc(-c2nc3ncccc3o2)c1C +Cc1cccc(N2CCN(CCC(=O)c3cccc(N)c3)CC2)c1 +CCOC(=O)CCC(=O)c1ccc(NC(C)=O)cc1 +NC(=O)C1(NC(=O)c2ccc(-c3ccccc3Cl)o2)CCCOC1 +CNC(=O)c1cc(Cl)ccc1NCc1nnnn1-c1ccccc1 +O=C(CCC(O)c1cc(F)ccc1F)NC1CC1 +CCCNS(=O)(=O)c1cc(C(F)(F)F)ccc1Cl +O=c1[nH]c(-c2cccc(O)c2)nc2c1cnn2-c1ccccc1 +CC(C)c1nc(C2CCCN(c3cccc(F)c3C#N)C2)no1 +CCN(CC)S(=O)(=O)c1ccc(-c2nc(C)ccc2OC)cc1 +CN(C)S(=O)(=O)CCNC(=O)c1cc(-c2ccccc2F)n[nH]1 +CC(Cc1ccco1)NC(=O)c1cc2c([nH]c1=O)CCCC2=O +COCCOc1ccc(NC(=O)C2CCC(=O)NC2)cn1 +CC(C)CCNS(=O)(=O)c1ccccc1Cl +O=C(NCc1ccccc1)Nc1ccc(-n2cncn2)c(F)c1 +CC(C)(CNC(=O)c1ccccc1OCC(N)=O)c1ccncc1 +COc1ccc(F)cc1S(=O)(=O)NCc1ccco1 +COc1ccc(F)cc1NC(=O)CN(C)c1ccccc1 +CCNC(=O)Nc1ccc(S(=O)(=O)N(CC)CC)cc1 +COc1c(F)ccc2c1C(c1ncccn1)NCC2 +Cc1ccc(NC(=O)Nc2cccc(F)c2)c(N)c1 +COCCN(C1CCCC1)S(=O)(=O)c1ccc2c(c1)CCC2 +CC(C)COCCC(=O)C(C#N)c1nnc2n1CCCCC2 +COc1ccc(-n2ccc(C)c(C#N)c2=O)cc1Cl +O=C1OC(C(=O)Nc2cccc(F)c2)Cc2ccccc21 +O=C(Nc1nc(-c2ccccn2)cs1)c1ccc(Cl)cc1 +CC(CCC1CCCO1)NC(=O)c1ccc(F)cc1Br +COc1cccc(COC(=O)c2cc(C(N)=O)cs2)c1 +COc1ccc2c(c1OC)CN(c1ccccc1)C2=O +COCC(=O)N1CCN(C(=O)c2c(F)cccc2Cl)CC1 +COc1cccc(C(=O)c2c[nH]c3ccc(C)cc3c2=O)c1 +COCC(=O)c1ccc(OCCC(C)C)c(N)c1 +N#CC1(C(=O)OCc2coc(-c3cccs3)n2)CCCC1 +Cc1ccc(CNC(=O)N2CCCC(NS(C)(=O)=O)C2)c(C)c1 +Cc1cc(CNC(=O)Nc2ccc(F)cc2)c(C)o1 +CCC(C)NS(=O)(=O)c1ccc(OC(F)(F)F)cc1 +Cn1c(=O)c2c(ncn2CCCOc2ccc(Cl)cc2)n(C)c1=O +COC(=O)COc1c(C(C)O)ccc2ccccc12 +Cc1csc(N2CCC(C(=O)N3CCOCC3C3CC3)CC2)n1 +CNS(=O)(=O)c1ccc2c(c1)nc(-c1cnn(C(C)(C)C)c1)n2C +COc1ccc(OC)c(-c2csc(NC(=O)c3ccccn3)n2)c1 +Cc1cc(C2CCCN2S(=O)(=O)c2ccc(Cl)cc2)no1 +O=S(=O)(Nc1cn[nH]c1)c1ccc(F)c(Cl)c1 +OC1CCN(c2ccnc(NCC(O)Cc3ccccc3)n2)CC1 +O=C(c1cccnc1)N1CCNC(c2ccccc2)C1 +O=C(Nc1ccc(NC(=O)C2CC2)cc1)c1c[nH]c2cccc(F)c12 +N#CC(C(=O)c1cc2cccc(Br)c2o1)c1ccccn1 +Cc1cnn(CCC(=O)N(C)CCOc2cccc(Cl)c2)c1 +Cc1ccc(CN2CC(N(C)C)C3OCCCC32)o1 +Cc1nc(C)c(CC(=O)Nc2ccnn2C(C)C)c(=O)[nH]1 +CCc1nnc(SCCC(=O)Nc2ccc(C)c(C)c2)n1N +C=CCNS(=O)(=O)c1cccc(C(=O)OC2CCCC2)c1 +Cc1cc(C(=O)N2CCN(C(=O)COCC3CC3)CC2)c(C)o1 +Cc1cc(Cl)cn2cc(Cn3cc(N)ccc3=O)nc12 +Cc1cc2n(n1)CCCN2C(=O)CCC(=O)Nc1ccccc1C +Cc1nnc(SCC(=O)NC2C3CC4CC(C3)CC2C4)s1 +NC(=O)c1ccsc1NC(=O)CCC(=O)N1CCCCC1 +C=CCNC(=O)CNC(=O)c1ccc(N2CCCC2=O)cc1 +Cc1cccc(NC(=O)NCC(O)COCC(C)C)c1C +Cc1nnc(SCC(=O)c2ccc(F)cc2)n1CC(N)=O +CC(C)(C)NC(=O)CSc1ccc(Cl)cc1N +CCc1cnc(NC(=O)NC(C(N)=O)C(C)C)s1 +COc1ccnc(N2CCN(C(=O)c3ncoc3C)CC2)n1 +C=CCN1C(=O)COc2ccc(NC(=O)c3ccccc3Cl)cc21 +CN(C)c1cc(N2CCCC(NC(=O)NCc3ccco3)C2)ncn1 +Cc1nn(C)c(C)c1C(=O)N(C)Cc1ccc(C(C)C)cc1 +COc1ccccc1C(NC(=O)c1ccc(C)[nH]c1=O)c1ccccc1 +Cc1n[nH]c(C2CCCN2C(=O)c2nn(C)c3ccccc23)n1 +CCC(=O)Nc1cccc(NC(=O)c2ccc(C)nc2)c1 +CC(C)N(CC1CC1)C(=O)c1cc(CN2CCOCC2)on1 +Clc1cccc(CCNc2ccc3nnnn3n2)c1Cl +Cc1ccccc1OCC(=O)N(C)Cc1ccco1 +COc1ccc(C(=O)Nc2ccccc2C(=O)N(C)C)nn1 +Cc1ccccc1C(=O)NCCCn1ncccc1=O +CCN(CC(F)(F)F)C(=O)Cc1csc(C)n1 +COc1cc(C)c(C(C)NC(=O)c2n[nH]c(=O)[nH]2)cc1OC +O=C(NCC#Cc1ccccc1)NCC1COCCO1 +COc1cccc(OC)c1COC(=O)C1COc2ccccc21 +Cc1cc(NC(=O)N(C)CC(C)(C)CN2CCOCC2)nn1C +Cc1cc(F)ccc1S(=O)(=O)NCc1sccc1C +CC(C)n1ncc2cc(NC(=O)c3cn(C)c4ccccc34)cnc21 +CC(=O)c1cc(C(=O)N(C)c2cccc3ccccc23)n(C)c1 +CCOC(=O)N1CCN(CC(=O)c2ccc(Cl)cc2Cl)CC1 +CCOC(CC)C(=O)NC1CCN(C(=O)c2ccccc2F)CC1 +COCc1ccc(C(=O)OCCc2c(C)n[nH]c2C)cc1 +O=C(Nc1cc[nH]n1)c1cc(-c2cccs2)n(-c2ccccc2)n1 +COc1ccc(C)cc1CCNC(=O)NCc1cnc(C)s1 +COc1ccc(CC(=O)OCc2nnnn2-c2ccccc2)cc1 +Cc1ccccc1C(C#N)N(C)C(=O)COc1ccccc1 +COc1cc(C(=O)NCCCC(C)C)sc1S(N)(=O)=O +COCCC(C)NC(=O)N1CCc2ccc(Cl)cc2C1 +Nc1cccc2ccc(CC(=O)N3CCCCC3)nc12 +Cc1nn(C)c(C)c1CCC(=O)NCCc1ccc(Cl)cc1 +COCCN(CCOC)C(=O)Nc1cnccc1C +Cc1ccc(-c2nc(C(=O)N(C)C3(C#N)CCC3)cs2)cc1 +COc1ccc(Oc2ncccc2NC(=O)Cc2ccco2)cc1 +O=C(Nc1nncs1)Nc1ccccc1Cl +CNC(=O)C1CCCN1C(=O)CSc1ccc(F)cc1 +COc1cccc(N2CCN(C(=O)NCCCn3cccn3)CC2)c1 +COc1ccccc1NC(C)C(=O)Nc1nccs1 +Cc1nn(CC(=O)NC(C)CN2CCOCC2)cc1Br +Cc1ccc(NC(C(N)=O)c2ccc(F)cc2)cc1Cl +CCNC(=O)CN(C)C(=O)c1ccc(C(N)=O)cc1 +O=c1ccccn1Cc1nnc(-c2cc3c(s2)CCCC3)o1 +Cc1ccc(C(=O)NCCc2cc3cc(C)c(C)cc3[nH]c2=O)cc1 +Cc1occc1CN(C)C(=O)NCCc1cccs1 +CC(C)(C)OC(=O)NCCC(=O)NC1CCCNC1=O +CCOc1ccc(S(=O)(=O)NC(C)c2ccncc2)cc1 +CCc1ccc(C(=O)OCCCc2ccncc2)o1 +CC(C)CC(=O)Nc1nnc(SCC(=O)NC2CCCC2)s1 +CC(C)CC(=O)N1CCC2(CC1)NC(=O)c1cc(F)c(F)cc1N2 +CCCOc1ccccc1-c1ncc(C(N)=O)c(N)n1 +CCn1cnc2c(nnn2Cc2ccccc2Cl)c1=O +COCC(C)N1CCN(C(=O)C2(C)CC2(Cl)Cl)CC1 +CC(C)(O)CCc1ccc(C(=O)N2CCCC2CO)cc1 +O=C(NCCc1nc(-c2cccnc2)n[nH]1)N1CCCC1 +CCN(CCO)C(=O)Nc1nnc(CC(C)C)s1 +C#CCN1CCN(C(=O)NCC2CCCc3ccccc32)CC1 +CCC(C(=O)NCc1nc2cccc(C)c2n1C)N1CCCC1=O +Cc1ccc(C(CNC(=O)c2ccc3c(c2)OCO3)OCCO)cc1 +COc1cc(F)ccc1NCc1cc(C)sc1C +CCCCC(C)NS(=O)(=O)c1ccc(C(C)O)cc1 +CCOc1ccccc1N1CCN(C(=O)c2ccco2)CC1 +CCCCn1ncc(-c2ccc(OC)cc2)c(CO)c1=O +CCc1nc(COC(=O)c2ccc(Cn3cccn3)cc2)cs1 +Cc1cccc(NC(=O)CN(C)C(=O)Cc2ccc[nH]2)n1 +CCOc1ccc(CNC(=O)Nc2ccc(C(C)=O)cc2)cc1OC +CC1=NC2(CCC3CN(c4ncccn4)CC32)C(=O)N1C +COc1ccc(CNC(=O)N2CCCCC2C)cn1 +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)CC(C)(C)C +O=C(NCc1ccc2c(c1)OCO2)c1cccc(N2CCCC2=O)c1 +Cc1cc(NC(=O)CNc2c(F)cccc2F)n(C(C)(C)C)n1 +Cc1ccc(NC(=O)c2c(C)c(N)c[nH]c2=O)c(C)c1 +Cc1cc(CNC(=O)C2(C#N)CCCCC2)ccc1F +CCn1ncc(C(=O)Nc2cc(C(C)(C)C)n[nH]2)c1C(F)(F)F +CCn1nc(C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)ccc1=O +CCCNC(=O)CCNC(=O)Nc1cccc(C(F)(F)F)c1 +CCOC(C)C(=O)N(Cc1cccnc1)c1ccc(F)cc1 +COc1ccccc1NC(=O)N1CCN2C(=O)NCC2C1 +CCOc1ccccc1NC(=O)c1nnn(-c2ccccc2F)c1N +COc1ccc(C(C)=O)cc1CC(=O)Nn1cnc2ccccc21 +CCc1c(C(=O)CN2CCOc3ccc(F)cc32)[nH]c(C)c1C(C)=O +Cc1cc(NC(=O)Cn2cc(C3CC3)nn2)c2ncccc2c1 +Nc1ccc(C(=O)NCC(=O)NCc2cn[nH]c2)cc1 +CN(Cc1ccc(Cl)cc1)C(=O)c1cncc(Br)c1 +Cn1cnc2ccc(-c3noc(CNC(=O)c4cccs4)n3)cc21 +Cc1cccc(-c2n[nH]c(C(N)c3ccccc3)n2)c1 +O=C(Nc1c(Cl)cccc1Cl)c1ccncc1 +Cc1nnc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)s1 +O=C(NC(Cc1ccccc1)C1CC1)c1cc(F)cc2[nH]cnc12 +Cc1cc(N2CCCC2)nc(N(CCO)Cc2ccccc2)c1C#N +NC(=O)C(Oc1ccc(Br)cc1F)c1ccccc1 +Cc1noc2ncc(C(=O)NCCNC(=O)OC(C)(C)C)cc12 +CCOC(=O)C(N)Cc1ccccc1CN1CCOCC1 +CC(O)CNc1ncnc2scc(-c3ccc(F)cc3)c12 +O=C(NCC1CCCCC1O)Nc1ccccc1C(F)(F)F +Cc1ccc(C(=O)NCc2nnc3ccccn23)cc1 +CC(=O)N1CCN(CCC(O)c2ccc3c(c2)CCC3)CC1 +CC1CCC(Nc2ccc(F)c(NC(=O)CCN3CCOCC3)c2)C1 +CC1CCN(C(=O)CSc2nnc3sc4ccccc4n23)CC1 +CCOC1CCC2C1OCCN2Cc1ccsc1 +CCCCOC(C)C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +CCOC(=O)c1nn(C)c2c1CN(C(=O)c1cnn(CC)c1)CC2 +COc1ccccc1C(C)=Cc1nc(-c2ccc(C#N)cn2)no1 +CC(C)n1c(CCNC(=O)c2c(F)cccc2F)nc2cccnc21 +COc1ccc(-c2n[nH]c(NC(=O)c3ccccc3F)n2)c(OC)c1 +c1ccc2c(c1)nc1n2C2(CCCC2)N=C2NCN(n3cnnc3)CN21 +CCc1oc(-c2ccc(OC)c(OC)c2)cc1CC#N +Fc1ccc(-c2cn(-c3ccc4nnnn4n3)cn2)cc1 +CCOCCCC(=O)Nc1n[nH]c(-c2ccccn2)n1 +CCn1cnnc1CN(C)C(=O)c1ccc(Cl)c(-n2cccc2)c1 +Cc1noc(C)c1CCC(=O)NCC1COc2ccccc2O1 +O=C(NCCOc1cccnc1)c1cccc(-c2ccoc2)c1 +CC(=O)N(C)CC(=O)NCCC(=O)NC1CCCC1 +COc1ccccc1Oc1ccc(NC(=O)c2ccoc2)cc1 +CCc1nnc(NC(=O)c2cnc(C)nc2N)s1 +Cc1ccc(N2CCC3(C2)CN(S(C)(=O)=O)CCC3(F)F)nn1 +CCSc1nnc(CSc2ccccc2)n1CC +CCCn1cc(CCNC(=O)c2ccc(OC)cc2)c2cccnc21 +O=C1CCc2cc(C(=O)NCc3cccc(C(F)(F)F)c3)ccc2N1 +CCOc1ccc(CN(C)C(=O)CNC(=O)C2CCCCC2)cc1 +CCCCN(C)C(=O)c1nc(C)n(-c2ccc(Cl)cc2)n1 +O=C1CCCc2[nH]c(=O)c(C(=O)OCc3ccc4c(c3)OCO4)cc21 +O=C(c1cccnc1C=Cc1ccccc1)N1CC2CCC1C2 +CCCNC(=O)C1CC(=O)N(c2cccc(C)c2)C1 +Nc1ncc(Br)cc1C(=O)N1CCCCC1CO +CC(=O)c1cccc(NC(=O)c2ccc(C#N)cc2)c1 +CCOC(=O)Nc1ccc(NC(=O)c2ccoc2)cc1 +Cc1cc(=O)oc2cc(OCCNc3ccccc3C(N)=O)ccc12 +CCC(C(=O)c1ccccc1)n1nnc2ccccc2c1=O +NC(=O)c1ccc(NC(=O)c2ccc(-c3ccc(Cl)cc3)o2)cc1 +CC(Cn1ccnc1)NS(=O)(=O)c1ccccc1OC(F)(F)F +CN(C(=O)c1cccc(N)c1)c1cccc(Cl)c1 +COc1cccc(-c2c3c(=O)n(C)ccc3nc3ncnn23)c1 +C#CCNC(=O)COC(=O)c1cc2ccccc2cc1O +NC(=O)c1ccc(NCc2nc(-c3ccsc3)no2)cc1Cl +Fc1ccccc1-n1cc(-c2ccnc(NCc3ccncc3)n2)cn1 +CC(Sc1cc(Cl)ccc1Cl)C(=O)NCc1ccncc1 +COc1cc2c(cc1OC)C(c1nccs1)NCC2 +COc1ccccc1C(=O)N(CC(=O)N(C)C)CC(F)(F)F +CCOC(=O)N1CCC(OC(=O)c2ccn[nH]2)CC1 +COc1ccc(CNC(=O)COC2CCCC2)cc1O +COC(=O)CCNC(=O)c1cc2cc(C)ccc2o1 +CCOCc1ccccc1NC(=O)c1ccc(-n2ccnn2)cc1 +CCc1c(C(=O)Nc2cccnc2)nnn1-c1ccccc1 +O=C(NCc1ccc2c(c1)OCCO2)c1cc(Cl)ccc1Cl +CCC(C)n1ncc(C(=O)N(C)C2CCC(C)CC2)c1C1CC1 +CC1(C(=O)N2CCc3ccccc32)Sc2ccccc2NC1=O +CC(=O)OCCOC(=O)c1cc(O)c2cc(N)ccc2c1 +CC(C)C(NC(=O)CCCC(=O)N(C)C)c1ccc2c(c1)OCCO2 +O=C(NCCc1cccs1)c1csc(-c2cnccn2)n1 +CC(Oc1ccc(F)cc1)C(=O)Nc1ccc(NC(=O)C2CC2)cc1 +Cc1ccc(S(=O)(=O)NC2CCC2)c(Br)c1 +CCc1nc(C)sc1-c1csc(NCC(C)C)n1 +Nc1nncc(-c2ccccn2)c1C(=O)Nc1ccccc1F +O=C(CC1CCc2ccccc21)NCCc1nc(-c2cccnc2)no1 +Cc1n[nH]c(C)c1NC(=O)CNC(=O)C12CC3CC(CC(C3)C1)C2 +Cc1oc2ncn(CCC(=O)N3CCC(C(N)=O)CC3)c(=O)c2c1C +COC(=O)C1(NC(=O)CN2CCOCC2C2CC2)CCCCC1 +COc1ccc(NC(=O)C2CC3CCC2O3)cc1F +COCCCCNC(=O)c1ccc(C(N)=O)nc1 +Cc1c(C#N)cnn1-c1ccc(Cl)c(C(F)(F)F)c1 +Cc1cc(C)n(CC(=O)N2CCN(C(=O)Cc3ccccn3)CC2)n1 +CC1CCC(NC(=O)CSc2nnc(C3CC3)n2C)CC1 +Cc1nc(CN2CCC3C2CC(=O)N3c2cncnc2)cs1 +NC(=O)CC1CCN(C(=O)C2CC(c3ccccc3)C2)CC1 +COc1cc(Br)cc(OC)c1OCC(F)F +Cc1ccc2c(NC(=O)c3ccc4c(c3)OCCO4)cccc2n1 +COc1ccc(CN(C)c2ccc3nnnn3n2)c(OC)c1OC +Cc1onc(-c2c(F)cccc2Cl)c1C(=O)NCc1ccco1 +CNC(=O)c1ccc(OC)c(NC(=O)NCc2cccnc2)c1 +Cc1cc2nc(N)nn2cc1NCC1(c2ccccc2)CC1 +O=C(NCCc1ccccn1)Nc1ccc(-n2cccn2)c(Cl)c1 +COc1ccc(C)c(C2NCCc3c(N)cc(F)cc32)c1 +Cc1nnc(C(=O)NCC(C)(C)C)n1-c1ccccc1 +Cc1ccc(C(=O)Nc2cccn(C)c2=O)cc1F +CC(=O)N1CCc2cc(NC(=O)CN3CCOC(C)C3)ccc21 +CCc1cc2c(NCCN3CCOCC3)nc(C)nc2s1 +COc1cccc(C(=O)N2CCC3(CCCCC3)C2)c1F +CC(C)OCc1cccc(CNC(=O)C2CCC2)c1 +CC(NC(C(N)=O)c1ccccc1)c1ccc(OC(F)(F)F)cc1 +Cn1cc(C(N)=O)cc1C(=O)NCC1(c2ccccc2)CCCC1 +Cc1ccccc1OC(=O)CCCNC(=O)c1cccs1 +Cc1cnc(C(=O)NC(C)c2ccc(C(F)(F)F)cc2)cn1 +COC(=O)c1cc(-c2cc(C)ccc2S(=O)(=O)C(C)C)nn1C +CC(=O)c1cnc(-c2ccc(Br)cc2)nc1C +Cc1ccccc1C1(CNS(C)(=O)=O)CCOCC1 +CC(NS(C)(=O)=O)C(=O)NCc1ncc(-c2ccccc2)[nH]1 +C=CCNS(=O)(=O)c1ccc(C(=O)Nc2ccc(F)cc2C)cc1 +Cc1nc(-c2ccc(N3CCCCCC3)c(N)c2)cs1 +CCOc1ccccc1NC(=O)CCc1cccc(N)c1 +CCCc1cc(C(=O)OCc2nc(C)no2)[nH]n1 +CC(C)N(C)S(=O)(=O)N(C)Cc1ccccc1OC(F)(F)F +CN(C)c1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)cc1 +CCOc1ncccc1CN(C)C(=O)c1ccccn1 +Cc1ccc(S(=O)(=O)CC(=O)NCc2ccccc2)cc1 +CCOc1ccc2cc(S(=O)(=O)Nc3ccncc3)ccc2c1 +CCc1nnc(COc2ccc(Cl)cc2C(N)=O)o1 +CCN(C(=O)Nc1cc(F)c(OC)cc1OC)C(C)c1cccnc1 +CCCCCCNS(=O)(=O)c1cncc(N)c1 +CC(=O)c1ccc(C(=O)NCCCn2c(C)nc3ccccc32)cc1 +Cc1cc(NC(=O)NCc2ccccc2OC(F)(F)F)n(C)n1 +COC(=O)c1cc(Cl)c(NC(=O)N2CCC(O)C2)cc1OC +CN1CCOC(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)C1 +COc1ccc(NCc2ccccc2C(F)(F)F)cn1 +CCc1cccc(C)c1NC(=O)c1ccc(OCC(N)=O)c(OC)c1 +Cc1cnc(SCc2cn3c(C)csc3n2)[nH]1 +CCCC(=O)Nc1cccc(NC(=O)CNC(=O)c2ccccc2)c1 +O=C(CN1CCOCC1C1CC1)Nc1ccc(Cl)c(Cl)c1 +COc1cccc(C(=O)N(C)Cc2ccccc2)c1F +COCCN1CC(c2nc(-c3cccc(Cl)c3)no2)CC1=O +CC(NC(=O)c1ccc2cccc(F)c2n1)c1nncn1C +CC1CCN(C(=O)Cc2cc(-c3ccccc3F)on2)CC1 +CC(CNC(=O)C(C)(C)C#N)N1CCc2ccccc21 +CC(C1CC1)N(Cc1ccccc1)C(=O)Cn1cnc(C#N)n1 +O=C(NCc1nc(-c2ccc(Cl)cc2)no1)Nc1ccncc1 +CNC(=O)C1CCC(Nc2nn3cc(C)nc3s2)CC1 +Cn1c(CN2CC(c3ccccc3)OCC2(C)C)nnc1C1CC1 +O=C(Cc1ccc2ccccc2c1)Nc1nnc(-c2ccno2)o1 +O=C(c1cncc(-c2ccc3c(c2)OCO3)n1)N1CCOCC1 +CC(C)Oc1ccc(F)cc1NC(=O)CC1OC(=O)c2ccccc21 +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)c1cccc(N(C)C)c1 +CCn1nnnc1SC(C)C(=O)C12CC3CC(CC(C3)C1)C2 +CNc1ncnc(Nc2ccc(Br)cc2)c1N +O=C(NCCc1ccc(Cl)cc1)c1nc(-c2cccnc2)no1 +O=c1[nH]c2ccccc2n1CCOc1ccc(F)cc1F +COC(=O)C(C)(C)NC(=O)c1ccn(-c2ccc(F)cc2)n1 +CCCNC(=O)c1ccc2c(c1)nc1n2CCCCC1 +O=C(c1ccoc1)N1CCN(CCn2cccn2)CC1 +COc1ccc(CCNC(=O)NCC(C)(O)c2ccsc2)cc1 +CCN(CCO)c1ncnc2sc(C(=O)OC)c(C)c12 +Cc1ccoc1C(=O)N1CCN(C(=O)Cn2cnnn2)CC1 +COC1(CNC(=O)C(C)C)C2CC3CC(C2)CC1C3 +C=C(C)CSc1ccc(S(=O)(=O)N2CCN(C)CC2)cn1 +O=C(NCCN1CCOCC1)N1CCCC1c1cccs1 +O=c1cc(CSc2nc(-c3ccccc3)c[nH]2)nc2ccccn12 +CCOc1ncccc1CNS(=O)(=O)c1ccc(C(C)=O)cc1 +O=c1[nH]c(=O)n(CCCOc2cccc3ccccc23)cc1Cl +Cc1nc2c(c(C)nn2C)c(C)c1CCC(=O)Nc1ccccc1O +COCc1c(C#N)nnn1-c1ccc(Cl)c(C(F)(F)F)c1 +O=C(CNC(=O)C1CCCCC1)Nc1cccnc1 +COc1cccc(C(=O)N2CCc3ccccc3CC2)c1F +CCC1CCCC(NC(=O)NCc2ccncc2)C1 +O=c1c2ccccc2nnn1CC(O)c1cc(Cl)ccc1Cl +CC(=O)NC1CCCN(C(=O)c2cc(Br)c[nH]2)C1 +O=C(NCc1ccco1)c1cccc(-n2nnc3cccnc32)c1 +CCOCCNC(=O)c1cc(S(C)(=O)=O)ccc1C +COCCN1C(=O)CC2C1CCN2C(=O)c1c[nH]cn1 +O=C(NCCN1CCN(C(=O)c2cnccn2)CC1)c1ccsc1 +Cc1csc(CCNc2ccc(N)cc2C#N)n1 +CC(OCCCNC(=O)C1CCC(=O)N1)c1ccccc1 +CC(=O)NCc1ccc(-c2nc3cc(C)c(C)cc3o2)cc1 +Cc1cccc(NC(=O)c2cncc(N)c2C)c1C +CCN(CC)C(=O)c1cccc(-c2ccccc2)c1 +O=C(c1ccc(C#CCCO)s1)N(CCO)C1CC1 +Cc1ccc(OCC(=O)NCc2nc3ccccc3[nH]2)cc1 +CC(C)C1NC(=O)C2CN(CC3CC3)CCN2C1=O +CSc1ncccc1C(=O)OCC(=O)NC1CCCC(C)C1C +CCCNC(=O)c1cc(S(=O)(=O)N(C)C)ccc1OC +COc1cc(C)c(C(C)C)cc1S(=O)(=O)n1ccnc1C +NC(=O)c1cccc(OC(=O)c2occc2COc2ccccc2)c1 +COc1cc(OC)nc(CSc2nc3ccccc3[nH]2)n1 +O=C(Nc1ccc(Cl)cc1)c1csc(-n2cccc2)n1 +COC(=O)c1c(C)[nH]c(C(=O)N(C)C(C)C)c1C +COc1ccc(NC(=O)NCc2ccccc2C)cc1OC(F)F +CCc1c(C)nc(N2CCN(CC(=O)NC3CC3)CC2)[nH]c1=O +COc1cccc(NC(=O)COc2ccc(C(=O)NC3CC3)cc2)c1 +CN(C(=O)CCC1CCCO1)C(c1cccc(F)c1)c1ccccn1 +O=c1n(CCOc2ccccc2F)nnn1-c1cccs1 +O=C(Cn1c(=O)cnc2ccccc21)NCc1ccccc1 +CS(=O)(=O)N1CCC2(CC(=O)N(c3cccc(C#N)c3)C2)C1 +CCC(=O)Nc1ccc(Oc2ccc(S(N)(=O)=O)cc2)cc1 +Cc1cc(OCn2nc(N)cc2C)ccc1C(C)C +CCN1CC2(CCC1=O)CCN(c1nc(C)c(C)cc1C#N)CC2 +c1cc(COC2CN(Cc3nccs3)C3CCCOC23)ccn1 +CC(=O)c1cc(C(C)=O)c2cc(C)cc(O)c2c1O +CCOC(=O)Cc1nccc(C(F)(F)F)c1Cl +Cc1nc(CCNC(=O)C2(C)Cc3ccccc3C(=O)O2)cs1 +Cc1cc(CN(C)C(=O)NCc2ccc(-n3ccnc3)c(F)c2)no1 +CCOC(C)C(=O)N1CCN(C(=O)c2cccs2)CC1 +N#Cc1ccc(S(=O)(=O)N2CCN(c3ccccc3F)CC2)cc1 +Cc1cccc(C)c1OCC(=O)Nc1cc(C(N)=O)cc(C(N)=O)c1 +c1cc2c(c(NCc3nc(C4CC4)no3)c1)CCCC2 +CC1CN(CCCCOc2ccccc2C#N)CC(C)O1 +COc1cccc2cc(C(=O)NC3(C#N)CCCC3)oc12 +Cc1ccc(S(=O)(=O)N(C)CCc2ccccc2)s1 +CCN(CC=Cc1ccccc1)C(=O)c1c(C)nn(CC)c1C +CCN(CC1CC1)C(=O)c1c(C)nn(-c2ccccc2)c1C +Cc1cc2c(o1)c1cnn(CC(=O)NC3CCC3)c(=O)c1n2C +CC(C)(C)c1nnc(CNc2ccccc2C(N)=O)o1 +O=C(CCc1ccncc1)NC1CC2CC1C1CCCC21 +Cc1ocnc1CNC(=O)NC1CCC(C)(C)CC1 +O=C(NCC(O)c1ccc(F)cc1)c1ccc2c(c1)OCCO2 +CCOc1ccccc1OCC(=O)Nc1cc(Cl)ccc1C(N)=O +CCS(=O)(=O)N1CCC(C(=O)NCCO)CC1 +COc1ccc(NC(=O)C2CSc3nccc(=O)n3C2)cc1OC +Cc1c(C(=O)NC(C)(C)CCO)sc2cccc(F)c12 +COc1ccc(NC(=O)c2csc(NC3CC3)n2)cc1Cl +Cc1ccc(N(C)CC(=O)Nc2c(C)n[nH]c2C)c(C)c1 +c1cncc(CCNc2ncnc3sccc23)c1 +NC(=O)CSc1nc(-c2ccccc2)cc(C(F)(F)F)n1 +COCc1ccccc1NCc1cn2c(C)cc(C)nc2n1 +CC(C)c1ccc(C23COCC(=O)N2CCCN3)cc1 +O=C(Cc1cccs1)N1CCCCC1c1nncn1CC1CC1 +CNC(=O)C1(NS(=O)(=O)c2ccc(F)cc2C)CCCC1 +COc1ccccc1C(=O)OCC(=O)Nc1c(C)cccc1C(C)C +Cc1ccc(-n2cc(C(=O)N3CCOCC3)nn2)cc1C +COc1ccccc1CNC(=O)C1CC(=O)N(c2ccccc2)C1 +O=C(NCCO)c1cc2c(ccc3ccccc32)[nH]1 +NC(=O)c1cccnc1N1CCOC(Cc2ccccc2)C1 +CCOC(=O)c1c(C2CC2)csc1NC(=O)c1ccc(C)cc1 +COCC(C)NC(=O)c1sc2ncnc(N3CCCCC3)c2c1C +CCOc1cccc(C(=O)Nc2cnn(CC3CC3)c2)c1 +COc1ccnc(N2CC(S(=O)(=O)N3CCOCC3)C2)n1 +CC(C)COC(=O)N1CCCN(C(=O)C2CC=CC2)CC1 +COCC(C)NC(=O)c1cc(F)cc2[nH]cnc12 +COCCCNC(=O)C1(c2ccc(Cl)cc2)CCC1 +Cn1cc(C(=O)CC2CCCN2c2ncc(Cl)cn2)cn1 +COCC(C)NC(=O)c1ccc(OC(F)(F)F)cc1 +O=C(Cc1ccc[nH]1)NCc1nc(-c2ccccc2)cs1 +CNC(=O)NCC(=O)NC(C)c1cccc(C(F)(F)F)c1 +Cc1cccc(C)c1OCCNC(=O)CNS(C)(=O)=O +Cc1nc[nH]c1-c1nccn1C(C)c1cccs1 +CCOc1ccc(Cl)cc1S(=O)(=O)N1CCCC(C(N)=O)C1 +Nc1nc(SCC(=O)NCC(=O)c2ccccc2)n[nH]1 +Cc1ccc(S(=O)(=O)Nc2ccc(N3CCCC3=O)cc2)cc1 +CC(C)Cc1ncc2c(n1)CN(C(=O)c1cc(F)cc(C#N)c1)C2 +CCS(=O)(=O)N1CCC2OC(c3nc(C)no3)CC2C1 +O=C(Nc1cccc(-n2cccn2)c1)c1cscn1 +O=C(Nc1ccc(Cl)c(Cl)c1)N1CCCC1 +CCC1CCCCN1C(=O)c1cc2n(n1)CCCO2 +Nc1cccc(CNS(=O)(=O)c2cc3ccccc3o2)c1 +CCC(=O)c1ccc(S(=O)(=O)C(C)C(=O)OC(C)C)cc1 +Cc1cc(C)c2cc(OCc3nnc(C)o3)ccc2n1 +NC(=O)C1CCN(C(=O)CCc2ccco2)CC1 +C=CCN(CC=C)C(=O)C(C)NC(=O)c1cn(C)nc1C +C#CCNC(=O)COc1cc(Cl)ccc1Cl +CC(C)Cc1ncc2c(n1)CN(c1ncccc1C(N)=O)C2 +O=C(c1cc(NCC2(Cn3cccn3)CC2)ccn1)N1CCOCC1 +O=C1CC(C(=O)N2CCCC(n3cccn3)C2)c2ccccc2N1 +CC(=O)Nc1ccc(C(=O)Cn2cnc3ccsc3c2=O)cc1 +NC(=O)CCN(C(=O)COc1ccccc1)c1ccccc1 +CN(Cc1ccccn1)C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +Cn1nnnc1-c1cccc(NC(=O)CCc2ccco2)c1 +CCSc1ccc(Cl)cc1NC(=O)N(C)C(C)CC#N +O=C(NCc1cscn1)N1CCCC1c1ccncc1 +N#CCCC(C#N)CN1CCCN(S(=O)(=O)c2ccccc2)CC1 +CCS(=O)(=O)c1ccccc1NC(=O)c1ccc(Cl)cc1 +CC1=NCCNC2=C1C(c1ccccc1)N(c1ccccc1)C2=O +N#Cc1cc(F)cc(C(=O)N2CCC(OCc3cccnc3)CC2)c1 +CC(C)CNC(=O)CSc1ccc2c(c1)OCCO2 +CS(=O)(=O)c1cccc(OCC(=O)N2CCOCC2)c1 +Cc1ccccc1CNC(=O)COC(=O)c1ccsc1 +Oc1ccc2c3c(ccc2c1)CCNC3c1cccnc1F +CCC(C)Nc1nnc(-c2cnc(N3CCCC3)s2)s1 +O=C(Nc1ccc(N2CCNC2=O)cc1)Nc1cccnc1 +O=C(CCSc1cccc2cccnc12)Nc1ccccc1 +CCCn1nc(C(=O)Nc2n[nH]c(-c3ccc(C)cc3)n2)ccc1=O +CCCCNC(=O)NCc1ccc(S(N)(=O)=O)cc1 +CCOC(=O)N1CCN(C(=O)Nc2c[nH]c3ccccc3c2=O)CC1 +COCCCC(=O)OCc1cccc(Br)c1C +Cc1cccc(CNC(=O)Cn2c(=O)c(=O)n(C)c3ccccc32)c1 +CC(C)Cn1cc(O)c(=O)cc1CN1CC(C)OC(C)C1 +CC(C)(C)Cc1nnc(NC(=O)C2CCCO2)s1 +CCOc1ccc(NC(=O)C2CCCN(C(=O)CC)C2)c(C(N)=O)c1 +COCCOc1cc(C)ccc1NCc1cc[nH]n1 +CCOC(=O)CN(C(=O)c1cc(F)cc(F)c1)C1CC1 +O=C(CCCc1ccccc1)NC1c2ccccc2CC1O +Cc1ccc(-c2cc(C(=O)N(C)C(C)C)on2)cc1 +NC(=O)CCSc1nnc(-c2ccco2)n1Cc1ccccc1 +Cc1nc(-c2c[nH]c(C(=O)Nc3ccc(F)c(C#N)c3)c2)cs1 +O=C(NCc1cccc(F)c1)Nc1ccc(F)cc1 +O=C(NCCOc1ccc(Br)cc1)c1cnns1 +CCCCOc1ccc(-n2nnc(C#N)c2C2CC2)cc1 +Cc1ccc(C)c(OC(C)C(=O)Nc2cccc(N)c2)c1 +COC(=O)N1CCC(CNC(=O)c2ccc(Cl)cc2Cl)CC1 +COc1ccc(COCCCC(=O)N2CCOCC2C)cc1 +CCCCN(C)C(=O)c1[nH]c(C)c(C(C)=O)c1C +Cc1cc(NC(=O)CSc2nnc(C3CC3)n2C2CC2)n(C)n1 +Cc1nn(C(C)(C)C(=O)N(C)C)cc1Br +CC1(c2[nH]ncc2C(N)=O)CCCN(C(=O)c2ccccc2)C1 +CC(OC(=O)C1CC(=O)N(c2ccccc2)C1)C(=O)c1ccccc1 +C=C(C)Cn1c(CCCO)nc2cc(Cl)ccc21 +O=S1(=O)CCN2C=Nc3sc4c(c3C2=N1)CCCC4 +CCc1noc(-c2ccc(C)c(NC(=O)NCc3ccncc3)c2)n1 +CC(C)N(C(=O)C1CC1c1cccc(F)c1)C(C)C +COc1ccc(C(C)=O)c(OCC(=O)Nc2ccccc2Cl)c1 +C=CCNC(=O)c1cc(S(=O)(=O)N(CC)CC)ccc1C +COCCOc1ccc(CNC(=O)c2csc3c2CCCC3)cc1 +CCc1ccccc1CNC(=O)CNC(=O)C1CCCC1 +CNc1cc(C(=O)N2CCC3(CC2)c2ccccc2CC3O)ccn1 +CCCc1nnc2n1NC(c1ccc(Cl)cc1)S2 +CCN(CCc1ccncc1)Cc1cccc(CC#N)c1 +CCOc1ccc(CC(=O)Nc2cc(NC(C)=O)ccc2OC)cc1 +CC(=O)c1ccc(Sc2nccc(=O)[nH]2)c(F)c1 +CC1CN(C(=O)CSc2nnc(-c3ccccc3)n2N)CC(C)O1 +CCC1CN(C)c2ccccc2CN1C(=O)C1CCN(C(C)=O)C1 +O=C(Nc1ccc(F)cc1)c1cccnc1OCC(F)F +CNC(=O)CS(=O)(=O)c1nnc(NC2CCCCC2)s1 +CN(c1cccc(C(=O)NCCC2=CCCCC2)c1)S(C)(=O)=O +COc1cc(NC(C)=O)ccc1NC(=O)c1ccccc1Cl +O=C1CN(C(=O)Nc2ccc(-n3ncc4ccccc43)cc2)CCN1 +Cn1ccc2ccc(C(=O)Nc3cccc4ncccc34)cc21 +O=C(NC1CCN(C(=O)C2CC2)CC1)c1cccc(F)c1 +COc1ccccc1S(=O)(=O)NCC(O)c1sccc1C +Cc1ccc(NCC(=O)N2CCC3(CC2)OCCO3)c(F)c1 +Cc1cccc(C(=O)NCc2n[nH]c(=O)c3ccccc23)c1 +CC1CC(N2CCCC(c3nnc4ccccn34)C2)C(=O)O1 +CC(NC(=O)CCCCNC(N)=O)c1ccccc1 +NC(=O)c1cccc(OC(=O)c2ccc(-n3cccn3)cc2)c1 +CCc1noc(CC)c1CC(=O)NC(C)c1c(F)cccc1OC +CCCCN(CCCC)C(=O)c1nc2nccc(C)n2n1 +CC(CC(=O)Nc1cccc(N2CCCC2)c1)Nc1ncccn1 +Cc1ccc2ncc(C(=O)N(C)Cc3nnc(C4CC4)n3C)n2c1 +Cc1ccc(F)cc1NC(=O)c1cc(C)n(C2CC2)c1C +C=CCc1cc(C(=O)C(C#N)c2ccccn2)cc(OC)c1OC +O=C(CN1CCN(Cc2cc(F)ccc2F)CC1)c1cccs1 +Cc1noc(-c2cnc(NCc3ccncc3)nc2-c2ccco2)c1C +COCCOc1ccc(F)cc1NCc1csc(C)n1 +CC(=O)c1ccc(S(=O)(=O)N(C)C(=O)Cc2ccc(F)cc2)cc1 +Cc1cc2nnc(Sc3nccn(C4CC4)c3=O)n2c2ccccc12 +Cc1nc(CC(O)C(Cl)(Cl)Cl)c2cc(C)oc2n1 +COc1cccc(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1OC +CCn1c(C2CCN(Cc3sccc3C)C2)nc2cccnc21 +CC1CCCCN1C(=O)c1ccc(NC(=O)c2ccco2)cc1Cl +CCOC(=O)c1cnc2ccc(Br)cn12 +O=C(c1cccc2ncccc12)N1CCCC1c1ccccc1 +COc1cccc(CNc2ccc(-c3nc(C)c(C)c(=O)[nH]3)cn2)c1 +CCCn1nc(-c2cccs2)cc(CO)c1=O +O=S(=O)(Nc1cccc(CO)c1)c1ccccc1F +CCOC(=O)C(C)NS(=O)(=O)CC1CCCCC1 +CCOC(=O)CN(C)C(=O)C1(c2ccccc2)CC1 +COc1ccc(-c2nnc(SCC(=O)Nn3cnnc3)o2)cc1 +COc1ccc(CN2CCNc3ccc(C)cc32)cc1N +COc1ccccc1-n1nc(CC#N)c(=O)cc1C +Nc1ccc(SCC(=O)Nc2ccc(S(N)(=O)=O)cc2)cc1 +CC(O)CN(C)C(=O)c1c[nH]c2ccccc2c1=O +CCc1nnc2n1CCN(C(=O)c1ccc(C#N)c(C)n1)C2 +Nc1cc(CCC(=O)NCc2ccncc2)ccc1N1CCCC1 +CCOc1ncccc1NC(=O)N1CCCC1C(C)C +CC(O)c1nc2cc(N)ccc2n1CCN1CCOCC1 +COc1ccc(CC(=O)NCCc2cc(C)no2)cc1 +CCOC(=O)c1nnn(-c2cccc(F)c2)c1N +Cc1cc(NC(=O)C(C)n2nnc3ccccc3c2=O)on1 +N#Cc1c(-c2cccnc2)c2c([nH]c1=O)-c1ccccc1OC2 +COc1cccc(CNc2[nH]c(C)c(C)c2C#N)n1 +OCc1cc(Cl)ccc1OCCOCC(F)(F)F +O=C(CCn1cnc2ccccc21)N1CCC(N2CCNC2=O)CC1 +Cc1cc(C(=O)Nc2nncs2)c2cnn(C(C)C)c2n1 +CCOCC1CCCN(C(=O)CN(C)C(=O)OC(C)(C)C)C1 +O=C(Cc1ccc[nH]1)NCc1ccc(Oc2cccnc2)c(F)c1 +N#CCCCOc1cccnc1NCc1ccc2c(c1)OCCO2 +Cc1ccncc1NC(=O)c1cc2c(C)nn(-c3ccccc3)c2s1 +CCOc1ccc(C2CC(c3ccccc3)Nc3ncnn32)cc1 +Brc1cccnc1SCc1nnc(-c2ccccc2)o1 +CCc1cc(Cc2nc(CCO)cs2)ccc1OC +CCn1cc(C(=O)N(CCOC)Cc2ccc(C#N)cc2)cn1 +CC(C)c1nc(C(=O)OCc2ccco2)cs1 +Fc1ccc(-c2nnc(CN3CCCC4(C3)OCCO4)o2)cc1 +CCN(C(=O)CC1CC2CCC1C2)c1ccc(F)cc1 +Cc1cccc(C(C(=O)NCCCn2c(C)cccc2=O)N(C)C)c1 +NC(c1cc(Br)cc(C(F)(F)F)c1)C(F)(F)F +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)Nc1cccc(C)n1)O2 +CCCCCNC(=O)N1CCC(c2nnc3n2CCC3)CC1 +c1ccc(Cc2nccc(N3CCn4cnnc4C3)n2)cc1 +COc1ccc(C(=O)Nc2cc(C)nn2C)c(OC)c1OC +COC(=O)C1CC(O)CN1CC1=Cc2ccccc2OC1 +CCc1nc2c(N)cccc2n1Cc1cccc(F)c1 +CN1CCc2c(c(C#N)nn2-c2ccc(CC#N)cc2)C1 +CC1(O)CCN(C(=O)c2n[nH]cc2Cl)CC1Cc1ccccc1 +CCCCCN(C(=O)c1cnn(-c2ccncc2)c1C)C(C)C +CC(C)C(NC(=O)C1CC(=O)N(c2ccccc2)C1)C(=O)NC1CC1 +Cc1ccc(C(=O)NCCc2ccc3ccccc3c2)c(=O)[nH]1 +CC(=O)Nc1ccc(NCc2cnn(C)c2)cc1Cl +Cc1ncc2c(n1)CCN(Cc1noc(C(C)(C)C)n1)C2 +COC(=O)N1CCC(NC(=O)C2(c3cccc(F)c3)CCCC2)CC1 +COc1ccc(N2CCN(CC(=O)N3CCCC(C)C3)C2=O)cc1 +COc1ccc(C(=O)Nc2cccc3cn[nH]c23)cc1Br +CCOC(=O)CCNS(=O)(=O)c1cccs1 +Cc1cc(C(=O)N(C)C(c2ccc(Cl)cc2)c2cccnc2)no1 +CCOc1ccc2nc(CN3CC(c4ccccn4)C3)ccc2c1 +CN(C(=O)Cn1cnc2cc(F)c(F)cc21)C1CCCCC1 +N#CCc1ccc(OCc2cccc(NC(=O)c3ccoc3)c2)cc1 +O=C(NCc1ccc(C(F)(F)F)cc1)c1cccn2nccc12 +CCc1nc(CNS(=O)(=O)c2ccc(C)c(N(C)C)c2)cs1 +Cc1nnc(SCC(=O)Nc2c(C(C)C)cccc2C(C)C)n1N +Cc1nc(CN2CC3CN(c4cccnc4)CC3C2=O)cs1 +O=C(CSc1cnccc1C(F)(F)F)NCCN1CCOCC1 +CCCCNC(=O)C1CCCN(C(=O)c2n[nH]c3ccccc23)C1 +Cc1nc(SC(C)C(=O)NCc2ccco2)n(C2CCCC2)c1C +COC(=O)c1ccc(C(=O)Nc2cc(C(N)=O)c(F)cc2F)s1 +CCn1cc(S(=O)(=O)NC(C)C(N)=O)c(N)n1 +Cn1cnnc1CCC(=O)N1CCC(C(O)Cc2ccccc2)CC1 +CCNC(=O)Nc1cc(C(=O)NCC(F)(F)F)ccc1C +CCn1nc(-c2ccc(OC)cc2)cc1C(=O)NC1CCCC1 +CC(NS(=O)(=O)c1cccs1)c1cccnc1 +CCCCN(C)S(=O)(=O)NC(C)c1ccc(C)s1 +CNC(=O)c1cccc(NC(=O)Cc2ccc(-n3cccc3)cc2)c1 +Cc1ccc2[nH]c3c(SCC(=O)NC(C)(C)C)ncnc3c2c1 +Cc1c[nH]nc1C1CCN(C(=O)Cc2cccnc2)C1 +Cc1c(C(=O)N(C)Cc2ccc(O)cc2)cnn1C +CCOC(=O)c1oc2ccccc2c1NC(=O)C1CC1 +N#CCc1noc(-c2cc(Cl)ccc2Cl)n1 +COc1nc(C2CC2)nc(NCc2ccccc2F)c1N +Cc1ccc(-n2nnc(CC(=O)NCc3ccc(O)cc3)c2C)cc1 +CC(C)C(=O)NCC(=O)Nc1cccc(C(F)(F)F)c1 +CNc1cc(C(=O)NCCCN2CCCC2=O)ccn1 +COc1ccc2nc(CNC(=O)c3cc4cccc(C)c4n3C)[nH]c2c1 +CCC(C)Oc1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +O=C(c1ccccn1)N1CCC1c1nc(-c2cccnc2)no1 +NS(=O)(=O)CCCC(=O)NCC12CC3CC(CC(C3)C1)C2 +Nc1nccnc1C(=O)Nc1ncc(Cc2cc(F)cc(F)c2)s1 +Cc1ccccc1CSc1nnc(C(F)(F)F)n1N +Cc1ccc(C(=O)NCCc2cn3ccccc3n2)c(=O)[nH]1 +C#CCNC(=O)N1CCN(CC(=O)N2CCc3ccccc32)CC1 +CCOCC1CCCN(C(=O)c2cc(NC(C)=O)ccc2O)C1 +O=C(Cc1cccs1)NCCCn1ccnc1-c1ccccc1 +O=C(Nc1cc(Cl)ccc1N1CCCCC1)N1CCCOCC1 +COCc1nc(CNc2cc(Cl)ccc2-n2cccn2)cs1 +O=C(CNC(=O)NCc1ccco1)NC1CCCCC1 +O=C(NCCN1CCCS1(=O)=O)C1COc2ccc(F)cc2C1 +Cc1cc(OCC(=O)OCC(=O)Nc2ccc(F)cc2)no1 +COc1ccc(C(=O)Nc2ccc(C)c(NC(=O)C3CC3)c2)cc1 +CC(=O)Nc1ccc(C(=O)c2cc(F)ccc2F)cc1 +CC(C)NC(=O)C1CCCC(NC(=O)Nc2ccc3c(c2)COC3)C1 +CN(C)c1ncc(C(=O)NCCc2ccccc2)c(N)n1 +O=C(NCCC1=CCOCC1)c1cnc2ccccn12 +Cc1nn(CC(=O)N2CCN(C(=O)CO)CC2)c(C)c1Cl +COc1cc2c(cc1OC)C(CC(=O)N(C)C)CC2=O +O=C(Oc1ccc(-n2cnnn2)cc1)c1cc2ccccc2o1 +Cn1ccsc1=NC(=O)c1cc(C2CC2)n(C(C)(C)C)n1 +O=C(OCc1cc(-c2ccc(F)cc2F)on1)c1ccncc1 +O=C(Cc1ccc[nH]1)Nc1ccc(NC(=O)c2ccco2)c(Cl)c1 +COC(=O)Cc1csc(NC(=O)c2ccc(O)c(Cl)c2)n1 +O=C(Nc1cccc(N2CCNC2=O)c1)c1ccccc1 +O=C(NCCc1cccs1)c1csc(Nc2ccccn2)n1 +O=C(Nc1ccc(F)cc1Cl)c1ccccn1 +CC(=O)c1c2c(nc3c(Cl)cccc13)CCN(C)C2 +CC(C)OCCCNC(=O)Nc1ccc(F)cc1Br +N#Cc1cccc(CN2C(=O)OCC2C(=O)NC2CC2)c1 +O=C1CN(S(=O)(=O)c2cccc(Cl)c2Cl)CCN1 +O=C(NCCCc1nc2ccccc2[nH]1)c1[nH]nc2c1CCCC2 +O=C(CSc1ncnc2ccsc12)c1cc(F)ccc1F +CC1CC(C)CN(S(=O)(=O)N2CCN(C(=O)C(C)(C)C)CC2)C1 +CCn1cc(CCC(=O)Nc2cnn(Cc3ccccc3)c2)c(C)n1 +CN(C)C(=O)C1Cc2ccccc2N(C)c2ccccc21 +CC(C)N(C)S(=O)(=O)Nc1ccc(CCO)cc1 +CCC1CCCN(C(=O)c2ccc(N3CCCCC3=O)cc2)C1 +CNC(=O)c1cccc(NCc2ccccc2Br)c1 +Cc1cc(S(=O)(=O)NCC#Cc2ccccc2)c(C)s1 +Cc1ccc(Oc2ccc(NC(=O)Cc3c(C)noc3C)cc2)nc1 +O=S(=O)(c1cccs1)N(CCO)Cc1ccco1 +Cc1ccc(OCc2ccc(C(F)(F)F)cc2)c(CO)n1 +COCCOc1cccc(C(=O)N(C(C)C)C2CCOCC2)c1 +COc1ccc(-n2ccnc2SCCC#N)c(OC)c1 +Cn1c(C(=O)Nc2ccc3c(c2)OCCO3)cc2ccc(F)cc21 +NC(=O)C(NC(=O)Cc1cc2ccccc2[nH]c1=O)c1ccccc1 +CC(C)Cc1ccc(-c2ccc(C#N)c(N)n2)cc1 +Cc1cc(C)c2c(c1)C(N)C(=O)N2Cc1ccccc1 +c1cc2c(cc1-c1nc3c(s1)CCCN3)OCCO2 +OC1CCN(c2cc(-c3cccnc3)nc(-c3cccnc3)n2)CC1 +O=C(Cc1cccc2ccccc12)Nc1ccc(N2CCCC2=O)cc1 +COc1cc(C#N)ccc1OS(=O)(=O)c1cccnc1 +COC(=O)c1n[nH]c2ccc(NC(=O)NCc3csc(C)n3)cc12 +CCCc1cc(C(=O)NCC(O)c2ccccc2)[nH]n1 +CC(C)CCNC(=O)CCC(=O)N=c1[nH]nc2ccccn12 +CN(C)C(=O)c1cccc(NC(=O)c2ccco2)c1 +Cn1nnc2c(SCC(=O)Nc3ccc(F)cc3F)ncnc21 +CC1Cc2ccccc2N1CCNC(=O)NCC1COCCO1 +CC(=O)c1noc(C)c1C(=O)Nc1nccs1 +O=C(Cn1ccc2ncccc2c1=O)NCCC(=O)NC1CCCC1 +COc1cccc(CN(C)C(=O)COc2ccccc2CO)c1 +COc1ccc(-c2nc(N(C)C)ncc2S(C)(=O)=O)cc1 +CCc1nc(CCNC(=O)C2CCOC2)sc1C +O=C(Nc1nccs1)c1nnc2ccccc2n1 +CCn1nnc2cc(C(=O)N(Cc3ccccc3)C3CC3)ccc21 +CC(c1ccccn1)N(C)C(=O)Nc1cccc(COCC2CC2)c1 +O=C(NCCCc1ccccn1)C(c1cccnc1)N1CCOCC1 +O=C(NCC(F)F)c1cc(-c2ccccc2)nc2ncnn12 +Cc1ncsc1CCOC(=O)c1cc(F)ccc1F +Cc1ccc(C(=O)N(C)Cc2cccnc2)cc1NC(=O)c1ccco1 +Cc1cccc(NC(=O)CCNC(=O)Nc2cccc3cccnc23)n1 +O=C(Cc1nc(Cc2ccc(Cl)cc2)n[nH]1)NC1CCCC1 +COc1ccc(-c2nc(CN3CCNC(=O)C3C)c(C)o2)c(C)c1C +O=C(NCC(O)Cc1ccccc1)c1cnccn1 +O=C(CC1CCCCC1)N1CCN(Cc2nc3ccccc3[nH]2)CC1 +Nc1nnnn1NCc1ccc(Cl)c(Cl)c1 +COC(=O)CN1C(=O)C(C(C)C)Oc2ccc(N)nc21 +CCOCn1cc(NC(=O)c2sc3ccccc3c2Cl)cn1 +CCOc1ncnc(Oc2ccccc2OC)c1N +CCOC(=O)c1c(C)n(C)c2ccc(OCC(N)=O)cc12 +Fc1c(Cl)ccc2c1CCNC2c1cccnc1 +O=C(NCCCN1CCCC1=O)Nc1ccc(-n2cncn2)nc1 +COC(=O)c1ccc(Cl)c(NC(=O)c2ccccn2)c1 +COc1ccccc1C1CNC(=O)c2nc(CO)[nH]c2C1 +Clc1ccc2cccnc2c1CN1CCOC(Cn2cccn2)C1 +Cc1nc(C2CCCN2Cc2nnc(C3CC3)o2)no1 +Cn1cc(Cl)c(C(=O)NC2CCC(C(C)(C)C)CC2)n1 +COC(=O)c1cc(Cn2cc(NC(=O)C(C)(C)C)cn2)c(C)s1 +Cc1ccccc1CCNC(=O)Cn1cc(Br)cn1 +CCc1nc(C(=O)NCc2cccc(NC(C)C)c2)c[nH]1 +COC(=O)c1sccc1NC(=O)c1cccc(=O)n1C +O=S(=O)(NCC(O)Cc1ccccc1)c1ccc2c(c1)OCCO2 +O=C1NCCCCC1n1ccnc1-c1cnc(-c2ccccn2)nc1 +Cc1nc2cc(F)ccc2cc1C(=O)Nc1nc(CC(N)=O)cs1 +CCOC1COC2(CCCN(C(=O)Cc3ccco3)C2)C1 +Cc1ccc(CC(=O)Nc2ccc(N3CCCC3)cn2)cc1 +CN(CCCNC(=O)c1cc(Br)c[nH]1)S(C)(=O)=O +CCOC(=O)C(C)NC(=O)c1ccc(O)cc1O +CC(Sc1ccc(N)cc1)C(=O)Nc1ccc2c(c1)OCCO2 +Cc1cc(C)n(-c2ncnc(NCCCN3CCOCC3)c2N)n1 +O=C(COc1ccccc1O)N1CCCC1Cc1ccccc1 +Cc1nn(CC(=O)N2CCN(C)CC2)c(C)c1Cl +CC(=O)Nc1cc(NCC(=O)N2CCCCCC2)ccc1F +CCNc1cc2c(nn1)CCN(C(=O)c1ccc3c(c1)nnn3C)C2 +COc1cc(OC)cc(C(=O)OCC(=O)N2CC(C)CC(C)C2)c1 +CS(=O)(=O)N1CCCC1C(=O)Nc1nnc(C2CC2)s1 +COC(=O)c1ccc(C(=O)Nc2ccn(C)n2)cc1 +CCCC1CN(C(=O)c2ccc(NC(=O)c3ccco3)cc2)CCO1 +CN(CC1CCC1)C(=O)NCc1ccnc(OCC2CC2)c1 +C=CCN(CC(F)(F)F)C(=O)c1ccc(-n2ccnn2)cc1 +CC(CC#N)N(C)C(=O)Nc1ccccc1C(=O)NC(C)(C)C +Cc1nccn1Cc1cccc(CNC(=O)N(C)Cc2ccccn2)c1 +O=C(CNC(=O)c1ccccc1)Nc1cccc2cnccc12 +O=S(=O)(NCC1CC1)c1ccc(N2CCN(CCO)CC2)nc1 +Cn1c(C(=O)NC(C)(C)C)nnc1-c1ccccc1 +COC(=O)c1ccc(OCC(=O)Nc2ccccc2OC)cc1 +Cc1n[nH]c(-c2cccc(CNC(=O)c3cccnc3)c2)n1 +CCCCc1ccc(-n2nc(CC#N)c(=O)cc2C)cc1 +COc1ccc(-c2nc(-c3nc[nH]n3)no2)cc1F +N#CCn1ccc(=O)c2cccc(C(F)(F)F)c21 +CC(=O)c1ccc(NC(=O)NC(C)(C)c2nccs2)cc1C +CCOC(=O)CSc1nnc(-c2ccc(F)cc2)o1 +CCCNC(=O)CNC(=O)Nc1cccc(-n2nc(C)cc2C)c1 +CCCC(=O)Nc1ccc(C(=O)Nc2cc(OC)ccc2OC)cc1 +Cc1ccccc1CC(=O)Nc1ccc(Cl)cn1 +CCN(Cc1ccccc1)C(=O)CNC(=O)N1CCc2ccccc21 +CCc1nnc(CN2CCN(C(C)c3nc(C4CC4)no3)CC2)o1 +CCc1cccc(C)c1NC(=O)NCc1ccco1 +COc1cc(NC(=O)c2c(C)[nH]c3ccccc23)ccc1NC(C)=O +Cn1cccc1C1CCCN1C(=O)NCc1cccc(O)c1 +Cc1nc(CNC(=O)c2cnn(C)c2)c(C)s1 +Cc1ccc(NC2(C(=O)NCc3ccccn3)CCCC2)cc1 +N#Cc1cccn2nc(-c3ccccc3C(F)(F)F)nc12 +CC(=O)N(Cc1ccccc1)CC(O)c1ccsc1 +C=CCN(CC(=O)Nc1cc(C)on1)C(=O)Cc1ccccc1 +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)Cn1cnnn1 +COCCCNC(=O)c1cn(-c2ccccc2)nc1-c1ccc(C)cc1 +CC1CN(CC(=O)NCCOc2ccc(F)cc2)C(C)CO1 +CCCNC(=O)CCNC(=O)NC1CCCC(C)C1C +Cc1ccccc1OCC(=O)N1CCN(CC(O)C(F)(F)F)CC1 +Cc1ccc(S(=O)(=O)N2CCN(CCO)CC2)c2cccnc12 +O=C(Cc1c[nH]c2cc(Cl)ccc12)NCCNC(=O)C1CCCC1 +COc1cccc(CN(C)C(=O)CC(O)c2cccc(F)c2)c1 +Cc1cccc(CS(=O)(=O)Nc2cccc(-n3cnnc3)c2)c1 +CC(C)COc1ccc(C(=O)N2CCCCCC2)cc1 +CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccc(F)cc2)CC1 +O=C(N=c1[nH]ccn1Cc1ccc(Br)cc1)C1CC1 +NC(=O)c1oc2ccccc2c1NC(=O)c1cc(Cl)cc(Cl)c1 +CCOC(=O)C1CCCN1C(=O)c1cc(C)oc1C +CCCc1nnsc1C(=O)NCC1CCN(c2ncccn2)CC1 +CCCc1c(C(=O)Nc2cccnc2)cnn1Cc1ccccc1 +O=C(c1ccccc1-n1cncn1)N1CCC2(CCCO2)CC1 +CCN(Cc1cccs1)C(=O)c1cc(OC)ccc1OC +CS(=O)(=O)N1CCN(Cc2ccc(-n3cccn3)cc2)CC1 +CC(=O)Nc1ccc2nc(NC(=O)c3c(F)cccc3F)sc2c1 +COc1cccc(C(=O)Nc2cccc(-n3cnnn3)c2)c1F +CC1CN(C(=O)c2cccc(F)c2Cl)CCN1S(C)(=O)=O +Cn1cc(C(=O)NC2CCc3ccccc32)c(C(C)(C)C)n1 +CC(C)c1ccccc1NC(=O)Cn1nnc2ccccc21 +CC(Sc1nncn1C)C(=O)NC1(C#N)CCCCC1 +COc1cccc(CCNC(=O)c2ccc(OC)nn2)c1 +O=C(NCc1cn2ccccc2n1)NCC(F)(F)F +CC(C)(C(=O)Nc1ccccc1Cl)n1cc(Br)cn1 +O=C(Oc1cccc(N2CCCC2=O)c1)c1cc(Cl)ccn1 +CC(C)CNC(=O)c1ccccc1NS(=O)(=O)c1cccs1 +COc1cc(C(C)NS(C)(=O)=O)ccc1OCc1ccncc1 +Cc1cc2c(cc1C)NC(c1ccccc1O)=CC(=O)N2 +COc1cc(CNC(C)=O)ccc1OCc1ccccc1 +Nc1cc2c(cc1NCc1cccs1)NC(=O)C2 +CCCn1nc(-c2nnc(NC(C)C)s2)ccc1=O +CN(C(=O)c1scnc1C1CC1)C1CCN(S(C)(=O)=O)CC1 +COc1ccc2nc(CNc3cc(C)nc4c(C)c(C)nn34)[nH]c2c1 +CC(C)CNS(=O)(=O)c1ccc(Cl)c(N)c1 +CC(C)C(NC(=O)CNC(=O)c1ccccc1)c1ccccc1 +CC(NC(=O)Cc1cccc(OCC#N)c1)c1nnc2ccccn12 +Oc1ccc(C(O)C2NCCc3ccc4[nH]ccc4c32)cc1 +Cc1cc(C(=O)Nc2cccc(-n3cnnc3)c2)c(C)o1 +CC(=O)NC(C(=O)NCCc1nc(C(C)C)no1)C1CCCC1 +CC(C)(C)c1ccc(C2(C(=O)OCC3CCC(=O)N3)CC2)cc1 +COC(C(=O)Nc1ccc(Cl)cn1)c1ccccc1 +Cc1cc(C(=O)NCc2cnn(C)c2)ccc1NC(=O)CC(C)C +CCOC(=O)CC(NC(=O)c1cc(C)n[nH]1)c1ccc(F)cc1 +COc1ccc(C2CCc3nc(N)nn3C2)cc1OC +COCCOc1ccc(Cl)cc1S(=O)(=O)NC1C=CCCC1 +COc1ccc(CNC(=O)c2ccc(-n3ccnn3)cc2)cc1F +Cc1cc(C2CCCN(C(C)c3ccc(C#N)cc3)C2)n[nH]1 +N#Cc1cccc(COc2ccc(N3CCCC3=O)cc2)c1 +Cc1cccc(NC(=O)c2cccc(S(C)(=O)=O)c2)c1 +CC(C)c1nc(CNc2ccc(CN3CCCC3=O)cc2)cs1 +CC1(C(=O)NCCc2cccs2)Oc2ccccc2NC1=O +Cc1ccc(CC(=O)NCC(c2cccs2)N(C)C)cc1 +O=C(NCCN1CCNC1=O)c1cn2ccsc2n1 +Cc1ccc(NC(=O)c2cnc(-c3ccccc3)nc2N)nc1 +O=C(CSc1nnnn1C1CCCC1)c1ccc2c(c1)OCCO2 +COc1ccc(Cl)cc1-c1cc(NC(=O)C2CNC(=O)N2)[nH]n1 +O=C(NCCCN1CCOCC1)c1nc(-c2ccncc2)no1 +Nc1ccc(F)c2ccnc(C(=O)NCCCO)c12 +CC(C)c1cc(NC(=O)Cn2ccc(=O)c3ccccc32)[nH]n1 +Cc1ccc(C)c(OCC(=O)Nc2ccc(OCC#N)cc2)c1 +CC(C(=O)N1CCCC1)n1cnc2c1c(=O)n(C)c(=O)n2C +CCn1cnnc1CNC(=O)c1cncc(Br)c1 +COc1cc(C(=O)Nc2cccc(C)c2)ccc1OCC(N)=O +Cc1noc(C)c1CC(=O)Nc1cccc2[nH]ccc12 +Cc1nnc(-c2ccc(C(=O)NC(C)c3ccc(C)c(F)c3)cc2)o1 +CN(C)C(=O)N1CCN(C(=O)CNC(=O)C2CCCC2)CC1 +Cc1cc(C)n(CCNC(=O)C2(c3ccc(F)cc3)CC2)n1 +CC(=O)c1cccc(NC(=O)CN2CCN(c3ccccc3)C2=O)c1 +COc1ccc2ncc(-n3cc(CCO)cn3)cc2c1 +Cc1cc(C)nc(SCC(=O)Nc2c(C)nn(C)c2C)n1 +CCOc1ccc(NC(=O)c2cccs2)cc1CO +COc1ccc(CC(=O)OCc2cc(=O)n3ccsc3n2)cc1 +Cc1csc(=O)n1CCC(=O)NC1CC1c1cccc(Cl)c1 +COCCn1cc2c(n1)C(CNC(=O)c1cccs1)OCC2 +CCC(O)c1ccc2c(c1)CN(C(=O)c1ccc(C)cc1)CC2 +CCn1nc(C(C)C)cc1C(=O)NCC(C)(O)c1ccsc1 +CCNC(=O)c1cccc(NC(=O)NCc2cc(C)on2)c1 +CNC(=O)C1CCC(NC(=O)c2cccc(Br)c2)CC1 +Cc1ccccc1CNc1nc(N)n(-c2ccccc2)n1 +CC(C)(C)n1cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)cn1 +Cn1nc(NC2CCOCC2)c2ccc(Br)cc21 +CC(Sc1nncs1)C(=O)N1CCCc2ccccc21 +N#Cc1ccc(S(=O)(=O)CCn2ccnc2-c2cccs2)cc1 +CCCCn1c(SCc2ccccc2C#N)n[nH]c1=O +Cc1ccc(C(CNC(=O)C(C)C)N2CCOCC2)cc1 +CCC(C)NC(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +COc1c(C)cc(CNc2ccc(N3CCOCC3)cn2)cc1C +N#Cc1c(N2CCCCCC2)c2ccccc2oc1=O +CC(=O)N1CCCCC1C(=O)NCc1cnn(C)c1C +Cc1ccc2c(c1)N(CC(=O)N1CCCC1)C(=O)c1cccnc1O2 +O=C(Cn1nnc2ccccc2c1=O)Nc1ccncc1 +C1CCN(c2nc(N3CCOCC3)nc(N3CCOCC3)n2)CC1 +O=S(=O)(Cc1ccc(F)cc1)NCC1(O)CCc2ccccc21 +CC(C)C(NC(=O)C1CCCCC1)C(=O)NCc1ccccn1 +CCOC1C2CCC1N(C(=O)c1nn(C)c3ccccc13)CCO2 +Cc1ccc(Br)cc1NC(=O)CC#N +COc1cc(Cl)ccc1C(=O)NC1CCC(O)CC1 +Cn1cnc2cc(OC(=O)Cc3noc4ccccc34)ccc21 +Cc1c(CCC(=O)N2CCCC2)c(=O)n2c([nH]c3ccccc32)c1C#N +CC(C)c1c(C(=O)NCC2CCOC2)cnn1-c1ccccn1 +NC(=O)c1cccc(COC(=O)C2COc3ccccc32)c1 +O=C(Nc1cccc(COC2CCCCC2)c1)N(CCO)C1CC1 +Cc1cccc(C(N)=O)c1NCc1ncc(-c2cccs2)o1 +Nc1cc(C(F)(F)F)ccc1OCc1ccccn1 +CCOC(=O)c1ccccc1C(=O)c1cncc(Br)c1 +CC(C)C(CO)n1cnc2cccc(C(F)(F)F)c2c1=O +CC(Cc1cccs1)N(C)C(=O)c1cccc(OCC(F)F)n1 +Cc1cc(Cl)ccc1NC(=O)COc1ccc(-n2cnnn2)cc1 +Cc1c(NCC(=O)N(C)C)cccc1S(=O)(=O)NC1CC1 +CC1CCCN(S(=O)(=O)c2ccc(N3CCCC3=O)cc2)C1 +O=C(NCC1CCCO1)Nc1cccc(CSc2ccccn2)c1 +COCCN(C)C(=O)Nc1cc(Cl)cc(Cl)c1 +CCC(C(=O)Oc1ccc(NC(C)=O)cc1)c1ccccc1 +COCc1oc(-c2ccc3c(c2)OCCCO3)cc1C(C)=O +NC(=O)CNc1cc(C(F)(F)F)ccc1Cl +CC(C1CC1)N(CCC#N)Cc1nc2c(F)cccc2[nH]1 +CCN(Cc1ccccc1Cl)C(=O)CNC(C)=O +COc1ccc(Oc2ncnc(-n3nc(C)cc3C)c2N)cc1 +Cc1nc(C)c(C(=O)N2CCC(C(=O)NCc3ccco3)CC2)o1 +COCCN(Cc1ccccc1)C(=O)Nc1ccc(OC)cc1 +CC(C)Oc1cccc(C(=O)N2CCn3c(cccc3=O)C2)c1 +CSc1cccc(NC(=O)c2c[nH]c3ncccc23)c1 +Nc1ccc2c(c1)C(COc1ccccc1)NCC2 +CCOc1ccc(Cl)cc1CN(C)C(=O)c1cnc(C)[nH]c1=O +CN(Cc1ccccc1)C(=O)c1c(F)cccc1Cl +Nc1ccc(Cl)cc1-c1nn2cnnc2s1 +O=C1CCCc2cc(-c3csc(-c4cnccn4)n3)ccc2N1 +CC(NC(=O)C1CCC(=O)N1)c1ccc(Cl)cc1 +CC1COCCN1C(=O)Cn1c(C2CCCCC2)nc2ccccc21 +CC(Cc1ccccc1)C(=O)Oc1ccc2cn[nH]c2c1 +Cn1ncc(Cl)c1C(=O)Nc1ccc(F)cc1 +CC(O)c1ccccc1N1CCC2(CC1)OCCO2 +O=C(COc1ccccn1)Nc1ccc(F)cc1F +CN(Cc1ccc2c(c1)OCO2)C(=O)Cn1c(=O)[nH]c2ccccc21 +COCc1csc(NC(=O)N(C)Cc2cc(Cl)cn2C)n1 +COc1cccnc1NC(=O)Cc1nc(-c2ccsc2)oc1C +COc1ccc(C(=O)N2CCN(c3ccccc3Cl)CC2)nn1 +OCC(O)C1NCCc2ccc(-c3ccccn3)cc21 +Cc1cc(NC(=O)C(C)Oc2ccc(C#N)cc2)nc(C(C)C)n1 +COCCNC(=O)C12CCOC1CCN(Cc1nccs1)C2 +COC(=O)c1cc(C2CC2)nc2c1c(C)nn2-c1ccc(OC)cc1 +NC(=O)c1cccc(OC(=O)Cn2nc(-c3ccccc3)ccc2=O)c1 +CCN(C(=O)c1ccc2oc(C)cc2c1)C1CCOC(C)(C)C1 +O=C(Cn1c(=O)oc2ccccc21)N1CCCSc2ccccc21 +Cc1cc(C)cc(OCC#CCN2CCOCC2)c1 +Cc1cc(NC(=O)c2nn(-c3ccccc3F)c(C)cc2=O)[nH]n1 +Cc1n[nH]c(C)c1NC(=O)c1ccc(-n2ccnn2)cc1 +Cc1ccc(C(=O)NCCNC(=O)NC(C)c2ccc(C)o2)cc1 +COc1ccc(CC(=O)N2CCC(=O)CC2)c(OC)c1C +Cc1ccc(F)c(NC(=O)c2cccc(-n3cccn3)n2)c1 +CNc1cc(-c2ccc(OC(C)C)c(F)c2)nc(C)n1 +Cc1nc(Nc2ccc(NC(=O)C(C)C)cc2)cc(-n2cccn2)n1 +COC(c1ccc(Cl)cc1)C(C)NC(=O)N1CCCC(O)C1 +O=C(NCCCN1CCCC1=O)NCCc1ccsc1 +COc1ccc(NC(=O)C2CCN(c3ccc(C#N)cn3)CC2)cn1 +Cn1cc(C(=O)N2CCCC(c3cc(CO)[nH]n3)C2)cn1 +CN(CCC#N)Cc1coc(-c2ccc(S(C)(=O)=O)cc2)n1 +COCC(=O)N1CCCC(c2ccc(Nc3cnccn3)cn2)C1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1cc(C)cc(F)c1 +Cc1nc2ncnn2c(N)c1-c1ccc(Cl)cc1 +Nc1nnc(SCc2ccccc2OC(F)F)n1C1CC1 +CNC(=O)C1CCCN(Cc2cnc(C(C)(C)C)s2)C1 +Cc1cc(O)cc(C)c1C(N)c1nc(C)c(C)s1 +C=CCOC(=O)N1CC(C)NCC1Cc1ccccc1 +Cc1ccc(S(=O)(=O)NCCc2sc(C)nc2C)s1 +COc1ccc(CN2CCN(C(=O)c3ccc(C)s3)CC2)cc1O +c1csc(C2CN(Cc3cnc4cnccn34)CCO2)c1 +Cc1ncsc1C(=O)NCc1ccccc1F +CCCOC(=O)C1C2C=CC3(CN(c4ccc(OC)cc4)C(=O)C13)O2 +Cn1c(C2CC2)nc2cc(NC(=O)CCC(=O)c3ccccc3)ccc21 +Cc1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1F +Cn1c(NCCNc2cccc3ccccc23)c(C#N)c(=O)n(C)c1=O +Cc1oc2ncn(CC(=O)Nc3cccc(Cl)c3)c(=O)c2c1C +CC(C)CC(C)(NS(=O)(=O)c1cc(F)ccc1Cl)C(N)=O +CCCNC(=O)CCNC(=O)c1cc2c([nH]c1=O)CCCC2 +CCc1ccccc1OCC(=O)Nc1ccn(Cc2ccccn2)n1 +Cc1nc(-c2ccc3c(c2)CCN3C(=O)Cn2ccnc2)cs1 +Cc1ccc(-c2ccc(C(=O)NCCn3cnnc3C)s2)o1 +CC(Sc1nnnn1C(C)(C)C)C(=O)NC1CC1 +N#Cc1ccc(Cn2cc(C(F)(F)F)ccc2=O)c(F)c1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1ccc2c(c1)CCC(=O)N2 +CN1CCN(C(=O)c2nccc3c(N)cc(Cl)cc23)CC1 +Cc1ncc(CNC(=O)NCc2nncn2-c2ccccc2)s1 +Cc1cc(C(=O)OCC(=O)N2CCCC2)c(C)s1 +CCC(=O)NCC(=O)Nc1ccc(C)c(NC(=O)c2ccncc2)c1 +CC(C)NC(=O)Nc1cccc(-c2noc(-c3ccncc3)n2)c1 +CCNS(=O)(=O)c1ccc2oc(=O)ccc2c1 +Cc1c(C(=O)N2CCN(CC(C)O)CC2)sc2cccc(F)c12 +COc1c(O)ccc2c1C(c1ccc3cc[nH]c3c1)NCC2 +CCn1cc(NC(=O)N(C)Cc2csc(C)n2)cn1 +Cc1cc(C(=O)NCC2CN3CCCCC3CO2)c(C)s1 +CCC1COCCN1C(=O)CCCc1cc(F)ccc1F +CC(C)(C)OC(=O)N1CCNC(Cc2ccccc2)C1 +CCOc1cccc(NCc2c(C)nn(C)c2C)c1 +Cc1cccn2c(=O)c(NC(=O)c3ccc(F)cc3)cnc12 +C=C(C)Cn1cnc2c(oc3nc4c(cc32)COC(C)(C)C4)c1=O +Cc1ccn2ncc(C(=O)NCCCC(=O)NC(C)C)c2c1 +CNc1ccc(C2CN(c3cc(C)ncn3)CCO2)nc1 +CC(C)Oc1ccc(NC(=O)c2ccc(F)nc2)c(F)c1 +Cc1cc(F)ccc1C(O)CN(CCO)c1ccccc1 +COc1cccc(F)c1-c1cc(C(=O)N2CCN(C)CC2)ccn1 +Cc1nn(CC(C)C)cc1S(=O)(=O)N(C)Cc1cnn(C)c1C +Cc1nc2cc(NC(=O)NCc3ccccc3)ccc2n1C +CCc1nnnn1CC(=O)NC1(C#N)CCCCCC1 +N#CC(CC(=O)NC1CCCC1)c1ccc(F)cc1 +COc1ccc(F)cc1NC(=O)c1ccc(C#N)cc1C +COc1ccccc1CNC(=O)Cn1cc(C(C)=O)c2ccccc21 +CCN(Cc1cccc(C)c1)C(=O)c1cnn(-c2ccncc2)c1C +COc1cccnc1NC(=O)c1csc(NC(C)=O)n1 +Cc1cc(C)n(CC(C)CNC(=O)Nc2cccnc2)n1 +O=C1CCOc2c(cc(Cl)cc2C(F)(F)F)N1 +Cc1cc(C)nc(C(C#N)C(=O)C2CC2c2ccccc2C)n1 +COc1ccc(CNC(=O)C2(c3cccs3)CCOCC2)cc1 +OCCc1csc(COc2ccccc2Br)n1 +CCOC1CC1C(=O)N1CCOC(c2nc(C)n[nH]2)C1 +O=C(CNC(=O)c1ccc2sncc2c1)Nc1ccccc1 +CC(=O)c1csc(NC(=O)C(Cc2ccccc2)n2cnnn2)n1 +Cc1noc(C)c1NC(=O)Cn1cnc2c(C)cccc2c1=O +Cc1cc(C)cc(CSc2nnc(C)c(=O)n2N)c1 +CC(C)(C)OC(=O)N1CCC(CNC(=O)Nc2ccncc2)CC1 +COC(=O)c1cc(F)c(C)c(NC(=O)c2cn3cccnc3n2)c1 +Cc1c(N)cccc1OC(C)C(=O)NC1CCCC1 +CCCOc1ncccc1CNC(=O)N1CCOCC1C +COc1ccc(NC(=O)c2cnc3ccc(C)cn23)c(C)n1 +CCc1n[nH]c(C2CCN(C(=O)c3ccc4c(c3)OCO4)CC2)n1 +Cc1n[nH]cc1CN1CCOC(c2ccc(F)c(F)c2)C1 +NC(=O)COC(=O)C1(c2cccc(Br)c2)CC1 +Cc1nc(N)n(CC(=O)Nc2cccc(F)c2)c(=O)c1C +COc1cccc(CNc2ccc(NC(C)=O)cc2)c1 +COCCn1c(C)cc(C(=O)CN(C)c2ccccc2F)c1C +COCCC(=O)N(Cc1ccccc1)c1ccncc1 +O=C1COCC(C(O)c2ccc(NC(=O)c3ccccc3)cc2)N1 +COC(=O)Nc1sc2c(c1C#N)CCCCC2 +COc1cc(C(=O)N2CC(C)OC(C)C2)cc2c1OCCO2 +O=C(C1CC=CC1)N1CCN(c2ncnc3sccc23)CC1 +Cn1c(=O)c2c(ncn2CCOC(=O)c2cccnc2)n(C)c1=O +CC(CCc1ccc(OC(C)C)cc1)NC(=O)C1CNC(=O)N1 +CC(C)(CNC(=O)NCc1nc(C2CC2)no1)c1ccccc1Cl +Cc1ccc(N2CCC(C(=O)Nc3ccc(F)cc3)C2=O)cc1F +CC(C)CNC(=O)c1ccc(N(C)S(C)(=O)=O)cc1 +Cc1nc(C)c(C(=O)N2CCN(Cc3cccs3)CC2)s1 +CCc1nc(-c2cc(C)n(-c3nccs3)c2C)cs1 +O=C(CSc1nc2ccccc2o1)OCC(=O)N1CCCC1 +O=c1ccc2cc(S(=O)(=O)NCCN3CCOCC3)ccc2o1 +O=C(COc1ccccc1)NC1CCCc2ccccc21 +Cc1cc(NC(=O)COc2cccc(CC(N)=O)c2)no1 +CC(C)Oc1ncccc1CNC(=O)c1ccn(C)c(=O)c1 +CC(=O)c1c(C)[nH]c(C(=O)N(C)CC2CCCCC2)c1C +Cc1nn(-c2ccccc2)cc1CN1C(C)COCC1C +CCCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CCOCC +CN(CC(=O)Nc1cc(C(C)(C)C)ccc1O)c1cnccn1 +CC1CN(C(=O)c2nn(-c3ccccc3)c3c2CCCCC3)CCO1 +COC(=O)C(NC(=O)NCCC(C)C)c1ccccc1 +CCCc1noc(C(C)N2CCOC(c3ccc(F)cc3)C2)n1 +C=CCCC(=O)N1CCC(OCc2ccc(F)cc2)CC1 +Cc1ccccc1NC(=O)CSc1nnc(-c2ccncc2)o1 +COCCN(Cc1ccoc1)C(=O)Nc1ccccc1F +CC(CNC(=O)C1CC(=O)N(C)C1)N1CCc2ccccc21 +CCOc1cc(CNC(=O)c2cccc(Cl)c2)ccc1OC +COc1ccc(-c2nnc3n2NC(c2ccco2)S3)cc1 +Cc1ccc(N(C(=O)CCc2cnn(C)c2C)C(C)C)cc1 +COc1ccc(NC(=O)NCc2ccco2)cc1OC +CCCCCNC(=O)C1CC(=O)N(c2cccc(C)c2)C1 +Cc1cccc(NC(=O)N2CCCC2c2cccn2C)c1 +CNC(=O)c1c(C)nc(N)nc1-c1cccc(C)c1 +O=C(CCC(=O)c1cccs1)c1ccsc1 +Cc1nc(C)n(C(=O)N(c2ccccc2)c2ccccc2)n1 +COc1cccc(-c2cc(N)c3ccncc3c2)c1 +Cc1cc(NC(=O)CN2CCN(C(=O)NCCC(C)C)CC2)no1 +CCCC(C)(CO)NC(=O)NC1CCCC(C2CC2)C1 +Cc1ccc(N2CCC(c3nnc4n3CCCCC4)CC2)nn1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1ccncc1F +CCCSc1nnc(C2COc3ccccc3O2)o1 +NC(=O)C1CCN(C(=O)Cc2ccc3ccccc3c2)C1 +COCCCNC(=O)Cn1nnc(-c2cccs2)n1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)NCCCC(N)=O +COCCNC(=O)N1CCc2[nH]nc(-c3ccc(C)cc3)c2C1 +CCc1noc(C)c1NC(=O)Cc1cccc(OCC#N)c1 +CCCCn1nc(C(=O)NCc2cccs2)c2ccccc2c1=O +Cc1nc(C)c(CC(=O)N2CCOC(C)(C)C2)c(=O)[nH]1 +CC(C)c1cc(=O)n2c(n1)SCC2CC(=O)NC1CC1 +CC(C#N)NS(=O)(=O)c1cccc(C(C)C)c1 +CN(Cc1cnn(C)c1)C(=O)c1cc(S(C)(=O)=O)ccc1Cl +CCN(CC)S(=O)(=O)N1CCC(NC(=O)c2cc(C)no2)CC1 +COc1cc(CNc2cn(C)nc2C)ccc1OCC(F)(F)F +COc1cc(CNC(=O)CCNC(=O)c2cccs2)ccn1 +Cc1csc(=O)n1Cc1cc(=O)n2ccsc2n1 +CCc1cccc(C)c1NC(=O)c1ccc(-n2ccnn2)cc1 +NC(=O)C1CCN(C(=O)Nc2cnn(-c3ccccc3F)c2)CC1 +O=C(NCCc1ccccn1)c1ccc(Cl)c2cccnc12 +CC(=O)N(C)C(C)c1ccc(S(C)(=O)=O)cc1 +CNC(=O)Cn1nc(C#N)cc1-c1cc(Cl)ccc1C +Cc1c(C(=O)NCC(=O)OC(C)C)cnn1-c1ccncc1 +Cc1cccc(CCCOC(=O)c2scnc2C2CC2)n1 +Cc1sc(NC(=O)Cc2ccccc2)c(C(N)=O)c1C +CCC(C)C(C(=O)NCCc1nc(C)no1)c1ccccc1 +Cc1ccc(C)c(NC(=O)Cn2ccc3ccn(C)c3c2=O)c1 +COC(=O)C(C)NC(=O)COc1ccc2c(C)cc(=O)oc2c1 +COc1cc(Cl)ccc1CNC(=O)c1cccc(-n2cccn2)n1 +Cn1ccc(NC(=O)COc2cc(Cl)ccc2Cl)n1 +Cc1ccc(N)cc1Cc1cnc(N2CCCC2)s1 +CCNc1ccccc1C(=O)NCC(=O)OCC +CC(=O)Nc1cccc(C(C)NC(=O)CCOc2ccc(F)cc2)c1 +NC(=O)Cc1csc(NC(=O)COc2ccc3c(c2)C(=O)CC3)n1 +Cc1nc(CC(=O)NC(C)C(C)Oc2ccccc2)cs1 +CC(C)CCCC(C)NC(=O)C(C)n1nnc2ccccc2c1=O +Nc1nc(N)nc(SCC(=O)c2ccccc2)n1 +CCCc1nc(CN(CC)Cc2cnc3ccccc3n2)no1 +O=C(CCCc1ccc(Cl)cc1)NCC(O)c1ccccn1 +N#CCc1ccc(OS(=O)(=O)c2ccc(F)c(F)c2F)cc1 +CCC(CO)NC(=O)c1csc(NC(C)=O)n1 +O=C(Cn1nnc2ccccc21)OCc1nc2ccccc2s1 +CC1C(=O)Nc2c(F)cc(C(O)c3ccccc3Cl)cc21 +Cn1cc(C(=O)OCCOC(N)=O)c(-c2cccs2)n1 +COc1ccc(Nc2ncccc2C#N)cc1OC +CC(=O)c1ccc(C(=O)Nc2cccc(C)c2)s1 +CCCCCC1NC(=O)NC(C)=C1C(=O)OCC +O=C(Cn1ccc(=O)[nH]c1=O)N1CCN(c2ccccc2)C(=O)C1 +CCNC(=O)c1cccc(CNC(=O)NC(CC)CC)c1 +Cc1nc(C)c(CC(=O)NCCc2c[nH]c3ccccc23)c(=O)[nH]1 +CC(Sc1nncs1)C(=O)NCC(C)c1ccccc1 +Cc1cc(C)c(CN2CCCS2(=O)=O)c(C)c1 +Cc1ccc(S(=O)(=O)NCC(=O)Oc2ccccc2Cl)cc1 +COc1ccc(Cl)cc1NC(=O)CNC(=O)C1CCCC1 +Cc1nc(COc2ccc(NC(=O)c3cn[nH]n3)cc2)no1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)Nc1ccc(C(N)=O)cc1)O2 +OCc1cnc2c(Br)cc(C(F)(F)F)cn12 +N#CCSc1ccccc1NC(=O)CNc1ccc(C(N)=O)cc1 +CC(CCc1ccccc1)CC(=O)NC1(C(N)=O)CCCOC1 +Cc1ccc(OCc2cccc(C(=O)NCC(=O)NC3CC3)c2)cn1 +CCCc1nnc(N2CCN(C(=O)c3cccc(OC)c3)CC2)o1 +O=C(Nc1ccc2c(c1)OCCO2)c1cccc(-n2cccc2)c1 +Cc1oncc1C(=O)N1CCC2(CC1)NC(=O)CC2c1cccnc1 +c1cnc(N2CCOC3(CCCN(c4cnccn4)C3)C2)nc1 +O=C(NCc1nnc2n1CCC2)Nc1cc(-c2ccco2)ccc1F +CCOC(=O)C(C)(C)N1C(=O)CNc2cc(F)ccc21 +CC(C(=O)Nc1ccc(C#N)cc1)N1CCOC1=O +CCCn1nc(C(=O)Nc2ccc(SC(F)F)cc2)ccc1=O +COc1ccc(CC(=O)Nc2nnc(-c3ccnn3C)o2)cc1C +Cc1cccc(C)c1OCCn1nc2ccccn2c1=O +CCOc1ccc(C(=O)N(C)Cc2nccn2CC(F)(F)F)cc1 +Cc1cc(CCCC(=O)N2CCC(O)CC2)ccc1F +CC(=O)c1csc(NC(=O)C2COc3ccc(F)cc3C2)n1 +CC(CN1CCOC1=O)NC(=O)c1cccc2cc[nH]c12 +Cc1c(-c2ccc(NS(C)(=O)=O)cc2)nc2ccccn12 +O=C(NCc1cc(Br)cs1)C1CC2C=CC1C2 +Cc1nccnc1N(C)C1CCN(C(=O)OC(C)(C)C)CC1 +Cc1ccoc1C(=O)NC1CCN(S(=O)(=O)N2CCCC2)CC1 +CC(=O)NC1CCCN(C(=O)NCCCOC(C)C)C1 +COc1ccccc1S(=O)(=O)N1CCCC(C(N)=O)C1 +CC(C)NC(=O)N1CCC2(CC2C(=O)NCc2cccs2)C1 +CC(NC(=O)N(C)Cc1ccco1)c1csc(C2CC2)n1 +CSc1ccc(CN(C)C(=O)CC(C)(C)C)cc1 +CCOCC(=O)N1CCC2(CCN(c3ncccn3)CC2)C1 +Cc1ccccc1-n1ncc(C(=O)OCC2(C#N)CCOCC2)c1C +CC1CC(=O)N(C)c2cc(Cl)c(Cl)cc2O1 +COC(=O)C(NC(=O)c1cccc(S(C)(=O)=O)c1)C(C)C +Cc1ccc(Cl)cc1Nc1ncnc(NCc2ccco2)c1N +O=C(NCCCOc1cccc(Cl)c1)c1ccc2cncn2c1 +CC(C)COC(=O)N1CCN(C(=O)c2cccc(F)c2)CC1 +COc1ccc(OC)c(NCC(O)c2ccc(C)c(C)c2)c1 +CCCc1nc(C(=O)N2CCC(O)(c3ccccc3C)C2)cs1 +CCOC(=O)c1cnn(C)c1NC(=O)c1nc2ncccn2n1 +CCN(C)C(=O)C1CC(=O)N(c2cc(F)cc(F)c2)C1 +O=C(CCNC(=O)c1ccco1)NC1CCC(c2ccccc2)CC1 +CCCOc1cc(NCc2ccco2)nc(C(C)C)n1 +O=C(Cn1c(C2CCCCC2)nc2ccccc21)NCc1ncc[nH]1 +CNc1ncc(C(=O)NC2CC2(C)C)cc1Cl +COc1ccccc1OCCN1CCN(C(=O)c2cc(C)no2)CC1 +CCSc1ccc(C(=O)Nc2ncccc2OC)cn1 +Cc1nn(C)c2c(=O)n(C)c(Nc3ccc4c(c3)CCC4)nc12 +Cc1cc(CNC(=O)C2CCN(C(=O)C3CCCC3)CC2)n(C)n1 +COc1ccc(OCCCC(=O)Nc2nc(C)c(C)s2)cc1 +CCCN(CCO)C(=O)Nc1ccc(C(=O)NC)cc1 +N#Cc1c(F)cccc1NCCNC(=O)NCCn1cccc1 +CC(=O)c1ccc(C(=O)NCc2ccnc(N(C)C)n2)cc1 +CC(C)CCNC(=O)c1cn(C(C)C)c2cccc(N)c2c1=O +O=C(Cc1ccccc1)N1CCN(C(=O)c2ccccc2F)CC1 +COc1ccccc1-c1nc2c([nH]1)CCCNC2=O +O=C(Cc1cccs1)N1CCc2nc3cccnc3cc2C1 +Cc1cc(C(=O)NCC(=O)OCC2CC2)ccc1-n1cnnn1 +CCOC(=O)CN1CCC(c2nnc3n2CCCCC3)CC1 +CN(Cc1cscn1)C(=O)Nc1nc2ccccc2s1 +O=C(NCCCO)c1ccc(NC(=O)c2ccccc2)cc1 +CN(CCO)C(=O)Nc1ccc(OCc2ccccc2Cl)cc1 +CC(=O)NC(C(=O)Oc1ccccc1)C1CCCC1 +COc1ccc(CNC(=O)CNc2cccc(F)c2F)cc1 +CC(=O)N(Cc1ccc(NC(=O)N(C)C(C)CC#N)cc1)C(C)C +Cc1n[nH]c(C)c1NC(=O)c1csc2c1CCC(C)C2 +COc1ccc(CN2CCN(C(=O)c3cccn3C)CC2)cn1 +O=C1CCCN(C(=O)OCC2c3ccccc3-c3ccccc32)CC1 +CCCNC(=O)C(C)Oc1ccc(F)cc1Cl +Cc1ccc(CCNC(=O)N2CCC(CC(=O)N(C)C)CC2)cn1 +COCCNc1ncc(-c2cnccn2)c(-c2ccc(C)s2)n1 +Cc1cc(CN2CCN(C(=O)c3csnn3)CC2)no1 +Cc1ccnc(NC(=O)c2cc3c([nH]c2=O)CCCC3)c1 +Cn1cc(Br)c(C(=O)Nc2ccc(F)cc2)n1 +Cc1ccc(N2CC(C(=O)N3CCCC(O)C3)CC2=O)c(F)c1 +CN(Cc1ccccc1F)C(=O)COc1cccc(C#N)c1 +Cc1cc(NC(=O)NCCc2cccc(F)c2)n(C)n1 +CN(CC12CC3CC(CC(C3)C1)C2)S(C)(=O)=O +O=C(CCSc1nnc(-c2ccncc2)o1)Nc1ccc(F)cc1 +CNC(=O)c1nnsc1NC(=O)N1CCN(c2ncccn2)CC1 +COc1ccc(Cl)cc1NCc1nc2n(n1)CCCCC2 +Cc1cnc(C(=O)NCc2nc(-c3ccc(Cl)cc3)cs2)cn1 +CC(NC(=O)NCCNc1cnccn1)c1ccccn1 +COc1ccc2oc(C)c(C(=O)N3CCNC(=O)C3)c2c1 +Cc1ccn(-c2ccc(C(=O)NCc3cc(F)cc(F)c3)cn2)n1 +Cn1cc(N2C(=O)CCC3C2CCN3C(=O)N2CCOCC2)cn1 +Cc1cc(O)c(C(C)C)cc1NC(=O)CCSc1nnnn1C +Oc1cccc(C2NCCc3ccc4c(c32)OCO4)c1 +Cn1cc(C(=O)Nc2cc(F)ccc2F)c(C(C)(C)C)n1 +CCCN(C)c1cc(NC(=O)OC(C)(C)C)c(N)cc1C#N +CN(C)C(=O)c1ccc(C(=O)Nc2cccc(-n3cnnc3)c2)cc1 +CCCc1nnc2sc(NC(=O)c3ccc(OC)cc3)nn12 +CC(C)NS(=O)(=O)c1ccc(CCCO)cc1 +CCc1nnc2n1CCN(C(=O)C(C)OCC(C)C)C2 +COCCOc1ccccc1NC(=O)c1cc(F)ccc1OC +NC(=O)Cn1c2ccc(Cl)cc2c2nc3ccccc3nc21 +CC(N(C)C(=O)c1cccc2cn[nH]c12)C(C)(C)C +CCOC(=O)C(NC)c1ccc(OC)c(Br)c1 +Cc1cc(NC(=O)CNS(=O)(=O)c2cccs2)n(C)n1 +CCc1nc(CN2CCN(C(=O)Cc3ccc[nH]3)CC2)no1 +CCCS(=O)(=O)Nc1c(NCC)c2ccccc2oc1=O +Cc1cc(C(=O)C(C#N)c2ccccn2)c2c(C)nn(C)c2n1 +Cc1cc(CN2CCOC(c3noc(-c4ccccc4)n3)C2)on1 +CCCNC(=O)c1cccc(NS(=O)(=O)c2ccc(F)cc2)c1 +COc1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)cc1 +COc1ccc(-c2noc(CNC(=O)c3ccc(C)cc3)n2)cc1 +Cc1ccc(C(=O)NCC(C)CC2(C)OCCO2)cc1 +COC(=O)c1cccc(CCNC(=O)Nn2cnc3ccccc32)c1 +Cc1cc(C)c(NCCC(=O)c2cccc(N)c2)c(C)c1 +O=C(Nc1cccc(S(=O)(=O)Nc2ccccc2)c1)C1CC=CC1 +N#Cc1ccc(Oc2ccc3c(c2)CCC(=O)N3)nc1 +CSc1ccc(CNC(=O)NC(C)C2CCCO2)cc1 +CCN1C(=O)C(C)(C)c2cc(C(O)C(C)C)ccc21 +C=CCN(CC1CCCCC1)C(=O)c1ccncc1F +NC(=O)C1CCN(C(=O)Cc2c(F)cccc2Cl)C1 +Clc1ccc(OCCSc2ncn[nH]2)c(Cl)c1 +COc1cc(CNc2cnn(C)c2)cc(OC)c1OC +COC(=O)C(c1ccccc1Cl)N1CCC(OCC(C)C)CC1 +COc1ccc(C(=O)NCC(=O)c2ccc(C)cc2)cc1 +CC(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1 +COc1ccc(Br)cc1S(=O)(=O)NC(C)CC#N +CCc1cccc(NC(=O)NCc2cnn(C)c2)c1 +CC(C)(C)c1csc(SCC(=O)Nc2ncccn2)n1 +Cc1ccc(S(=O)(=O)NCCC(=O)NCC(C)C)cc1C +Cc1ccc(C(=O)CSc2nnc(C3CC3)n2C)cc1 +Cc1ncncc1C(=O)Nc1cnn(CC(=O)NC2CCCC2)c1 +CC1CCC(NC(=O)CCCNC(=O)c2ccsc2)CC1 +Cc1cc(C)c(N(C)C(=O)C2C3CC4OC(=O)C2C4C3)c(C)c1 +CCNC(=O)C1(NC(=O)c2ccoc2C)CCCCC1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)C1CC=CCC1 +CC(C)(CO)NC(=O)c1cncc(-c2ccc3c(c2)CCO3)c1 +CCOC(=O)c1nc(C(=O)OCC)c2cn[nH]c2n1 +Cc1nc(-c2cccc(NC(=O)Cn3cnnn3)c2)cs1 +COC(=O)c1ccc(C(=O)N2CCCN(C(C)=O)CC2)cc1 +CCCn1cc(N)cc1C(=O)NC(CC)C(C)C +CC(C)CN(Cc1ccc(OS(C)(=O)=O)cc1)C(=O)C1CCC1 +CCCn1c(C)cc(C(=O)COC(=O)c2nccnc2N)c1C +C=CCc1ccc(OCC(=O)Nc2cccc(C#N)c2)c(OC)c1 +O=C(CCCn1ccc2cc(Cl)ccc21)N1CCOCC1 +Cc1cc(C(C)NC(=O)Nc2cc(C(N)=O)ccc2F)c(C)s1 +CCn1cc(S(=O)(=O)NCc2ccc3c(c2)OCO3)c(C)n1 +COc1ccc(C(=O)NC2CC2)cc1Br +Cn1ncc2cc(C(=O)Nc3cccc(Cl)c3)c(N)nc21 +CN(C)c1nc(NCc2ccccc2)nc(SCC(N)=O)n1 +CCS(=O)(=O)c1ccc(NCc2cc(=O)n3ccsc3n2)cc1 +COCC(C)NC(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +CNC(=O)c1ccc(NC(=O)CCc2ccsc2)cc1Cl +COC(C)C(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +O=C(NC1CC1)c1cc(SCC(=O)N2CCC2)nc2ccccc12 +O=C(NCC1CCC1)c1cn(-c2ccccc2Cl)nn1 +COc1cccc(OC)c1C(=O)c1ccc(O)cc1 +COc1ccnc(NC(=O)C2(c3cccc(Br)c3)CC2)c1 +CCC(C)N(Cc1ccccc1)C(=O)c1ccc(C(N)=O)cc1 +CC(NC(=O)c1cccs1)C(=O)NC(C)C(=O)N1CCCC1 +COc1cccc(N2C(=O)NC3CC2(C)Oc2c(OC)cccc23)c1 +CSc1c(N)c[nH]c1-c1ccccc1Br +CCN1CC(C(=O)Nc2cc3c(cc2Cl)OCCCO3)CC1=O +CC(C)COCCCNC(=O)N1CCCC1c1nnc2ccccn12 +CCCCn1c(SCC(=O)Nc2ccccc2F)n[nH]c1=O +O=C(Nc1ccc(Br)cn1)c1cccnc1 +CCOC(=O)CN1CCCSc2ccccc21 +Cc1cc(OCC(=O)NCc2ccc3c(c2)OCO3)nnc1C +CSc1nc(C2CC2)cc(C(=O)OCc2c(C)noc2C)c1C#N +CCC1CCCN(C(=O)Nc2ccc3c(c2)OCC(=O)N3)C1 +Cc1ncccc1C(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +O=C(Nc1ccccn1)C1(c2cc(-c3cccs3)on2)CC1 +Cn1cc(CNC(=O)N2CCOCC2C2CC2)c(C(F)(F)F)n1 +O=C(Nc1cccc(-c2nnco2)c1)C1COc2ccc(F)cc2C1 +Cc1ccc(CC(=O)NC(C)(C)CNC(=O)OC(C)(C)C)cn1 +O=C(c1ccoc1)N1CCN(C(=O)c2cc(-c3ccco3)[nH]n2)CC1 +COC(=O)CN1CCOc2c(O)cc(-c3ccccc3C)cc2C1 +CC(CCc1ccccc1)CC(=O)N1CCN(CC(=O)N(C)C)CC1 +COC(=O)N1CCC(CNS(=O)(=O)c2ccc(C)c(C)c2)CC1 +CC(C)Cc1n[nH]c(SCC(=O)Nc2cccc(Cl)c2)n1 +Cc1cc(NC(=O)CCn2ncc3ccc(Cl)cc32)n(C)n1 +CC(C)(CNC(=O)N1CCC(n2cncn2)CC1)c1ccncc1 +O=C(c1ccccc1)C1CCN(C2CCOC2=O)CC1 +Cc1ccc(CNC(=O)COC(=O)c2cc(F)ccc2F)cc1C +CC1CN(C)CCN1C(=O)c1cnc2onc(CC(C)(C)C)c2c1 +COC(=O)CCNC(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +CC(Sc1ccccn1)C(=O)NCC(C)c1ccc(F)cc1F +O=C(NC1CCCCCC1)C1CCCN(C(=O)NC2CC2)C1 +CC(Sc1ccc(O)cc1)C(=O)Nc1ccc(Cl)cn1 +Cc1cnc(C(=O)N2CCC3CC(c4noc(C)n4)OC3C2)cn1 +COc1cccc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)c1 +COc1cc(C)c(C(C)NC(=O)c2scnc2C2CC2)cc1OC +CCOc1ccc(S(=O)(=O)N2CCC(Cn3cccn3)CC2)cc1 +Cc1cc2c(=O)n(CC(=O)N(C)C)cnc2s1 +CCc1noc(C(C)Sc2nnc(N3CCCC3)n2C2CC2)n1 +Cc1ccc(C(=O)N2CCC(c3nnc(-c4ccco4)o3)CC2)cc1 +Cc1nc(CN(C)C(=O)Nc2cc(-c3ccccc3)ns2)no1 +Brc1cc(Br)c2nc[nH]c2c1 +COc1ccccc1OC(C)C(=O)N1CCN(c2ccccc2)CC1 +CCOc1ccc2nc(C(=O)N(C)Cc3ccccc3)cn2n1 +CCOC(=O)N1CCN(C(C#N)c2cccs2)CC1 +N#CCOc1ccc(NS(=O)(=O)c2cccc(C#N)c2)cc1 +CCc1n[nH]c(SC(C)C(=O)NCCc2ccc(F)cc2)n1 +CC(C)NC(=O)CNC(=O)c1nn(C)c2ccc(F)cc2c1=O +Cc1cc(NS(=O)(=O)c2ccc(F)cc2)ccc1-n1cnnn1 +O=C(Nc1cc(C2CC2)[nH]n1)c1ccc(Br)cc1 +NC(=O)c1c(NC(=O)Cc2ccc(F)cc2)sc2c1CCC2 +Cc1nn(C)c(=O)c(C(=O)Nc2ccc3c(c2)oc2ccccc23)c1C +CNC(=O)c1ccc(NC(=O)C(Cc2ccccc2)NC(N)=O)cc1 +CCOC(=O)c1cnn(C2CCCN(C(=O)CC3=CCCCC3)C2)c1 +O=C(Cc1ccc2c(c1)OCCO2)N1CC=C(c2ccccc2)CC1 +CSc1cccc(NC(=O)Cn2cnc3ccccc32)c1 +COc1ccc(NC(C)=O)cc1NC(=O)c1cc(C)on1 +C=CCN(CC=C)C(=O)NCc1cc(C#N)ccc1F +CCOC(=O)CC1NCCc2ccc(C)c(F)c21 +Cn1cc(CCC(=O)NC(c2ccc(Cl)cc2)C(F)(F)F)cn1 +O=C1CN(C(=O)c2ccc(NCCC3=CCCCC3)nc2)CCN1 +CCC(CC)C(=O)NCC(C)(O)c1cccs1 +Cn1cc(CCNC(=O)CNC(=O)c2cc(F)cc(F)c2)cn1 +CCn1ncc(-c2ccc(OC)c(C)c2)c(CO)c1=O +Cc1nccnc1-c1c(Br)cnn1C +CCC1CCCCN1C(=O)C(C)Sc1nnc(C(C)(C)C)n1N +Clc1cccc(-c2nnc(SCc3noc(C4CC4)n3)o2)c1 +COc1ccc(C(=O)N(Cc2cc(OC)ccc2OC)C2CC2)cc1 +Cc1ccc(OS(=O)(=O)c2cccc(-n3cnnn3)c2)cc1C +CCc1noc(C)c1C(=O)N1CCCC1(C)C(=O)NC +CCCCNC(=O)C1CCN(c2nc3ccccc3o2)CC1 +COc1ccc2c(c1)C(c1ncccc1Cl)NCC2 +CCSc1cc(C(=O)Nc2ncn(CC(=O)N(C)C)n2)ccn1 +COCCN(Cc1cc(C)ccc1F)CC(F)F +CCCC1CCC(NS(=O)(=O)c2cccnc2)CC1 +O=C(NCC#Cc1ccc(F)cc1)C1CC=CCC1 +O=C(c1cncn1-c1ccccc1)N1CCCC(n2cccn2)C1 +COc1ccc(-c2cc3ncnc(N4CCNC(=O)C4)c3s2)cc1 +N#Cc1ccc(-c2csc(NC(=O)C3CCC3)n2)cc1 +CN(Cc1nc2ccccc2n1C)C(=O)c1ccco1 +O=C(NCCCn1ccnn1)c1c[nH]nc1-c1cccc(F)c1 +Fc1ccc2ncnc(NCC3CCN(CC(F)(F)F)C3)c2c1 +Cc1noc(C)c1CCC(=O)Nc1ccccc1N1CCCCC1 +COC(=O)C(C)Sc1nnnn1-c1cccc(C)c1 +O=C(CSc1nc2ccccc2o1)NCCOc1ccccc1 +CCCCC(=O)NCc1nc(-c2ccccc2OC)no1 +COc1ccc2[nH]c(CNC(=O)OC(C)(C)C)nc2n1 +Cc1cccc2cc(-c3noc(-c4ccc(F)cc4)n3)c(=O)[nH]c12 +N#Cc1ncn(Cc2ccc(Cl)cc2Cl)n1 +CCc1nnsc1C(=O)NCc1ccc(-n2ccnc2)cc1 +CCOc1cc(C)ccc1NC(=O)Cc1c(C)nn(C)c1C +CCOC(=O)c1c(C)oc2ncnc(NC(C)CC)c12 +CC(=O)NC(C(=O)Nc1cc(F)cc(F)c1)C1CCCC1 +O=C(NCCNC(=O)C1CC1)c1cc(Cl)ccc1F +CCCCN(C)S(=O)(=O)NCc1nnc2ccccn12 +CCCN1C(=O)C(C)Oc2ccc(C(=O)CN)cc21 +Cn1cc(C#N)c(=O)c2cc(F)c(N3CCCCCC3)cc21 +COCCCOc1ccccc1NC(=O)C1CC(=O)N(C)C1 +CCOc1cc(C)c(C(=O)c2nccn2C)cc1C +CCOC(=O)C1=C(C)N(CC2CC2)C(=O)NC1c1csc(CC)n1 +CC(C)c1nc(CC(=O)NCc2ccnc(OC3CCC3)c2)cs1 +CCOC(=O)c1nnn(-c2nonc2N)c1-c1ccccc1 +Cc1cc(CN(C)C(=O)c2cc(C)n(Cc3ccccc3)c2C)no1 +CC(=O)NC1C(=O)N(Cc2ccccc2)c2ccc(C)cc21 +NC(=O)c1sccc1S(=O)(=O)N1CCOCC1 +COc1ccc(CN2CCN(S(=O)(=O)C(C)C)CC2)cn1 +Cc1nc2ccc(NC(=O)NCCC(=O)N3CCCCC3)cc2s1 +Cc1ccc(NC(=O)c2coc(NC(=O)c3cnccn3)n2)cc1F +Cn1c2c(c(=O)n(C)c1=O)CN(Cc1cccs1)CN2 +CN(CC(=O)NC1CCCCNC1=O)S(C)(=O)=O +NC(=O)c1csc(-c2cnc3ccccc3c2)n1 +CCn1c(=O)oc2ccc(C(=O)Nc3cccc(C)c3C)cc21 +OCc1nc2cc3c(cc2n1Cc1ccccc1)OCCO3 +CCS(=O)(=O)NC(c1ccc(OC)cc1)c1nccn1C +CCc1c(C(C)O)oc2ccc3c(C)cc(=O)oc3c12 +Cc1nonc1CC(=O)N1CCN(c2cnn(C)c(=O)c2)CC1 +O=C(NCC1(c2ccccc2)CCOCC1)c1ccc[nH]1 +CC(C)CNC(=O)NCc1csc(-c2ccccc2)n1 +CCN(CC1COc2ccccc2O1)C(=O)Cc1ccc(F)c(F)c1 +COCC(C)NC(=O)c1ccc(OC)c(OC)c1 +CCCC(C)CC(=O)Nc1c(S(C)(=O)=O)cnc2cc(C)nn12 +COc1ccc(F)cc1C(=O)NCC(=O)OCc1ccccc1 +COC(=O)c1cc2n(n1)CCN(C(=O)c1cnc(C)nc1C)C2 +Cc1ccccc1-c1nnc(SCC(=O)NC(C)(C#N)C2CC2)o1 +COCCN(C(=O)c1ccc(O)cc1)C(C)COC +CCCC(C)N1CC(C(=O)NCc2ccc(F)cc2)CC1=O +Nc1ccccc1N(CCO)S(=O)(=O)N1CCCC1 +CCSc1nn2cc(-c3ccccc3)nc2s1 +CN(CCCc1n[nH]c(N)c1C#N)c1nccnc1C#N +COc1ccc(NC(=O)Nc2c(C)nc3ccccn3c2=O)cc1 +O=C(NCCCc1ccco1)C1CC(=O)N(Cc2cccnc2)C1 +COc1cccc(C(=O)NC(c2nc3ccccc3[nH]2)C(C)C)c1 +O=C(COc1ncnc2c(Cl)cc(Cl)cc12)NC1CCCC1 +COc1ccc(C(=O)NCCN2CCOCC2)cc1OC +CC(C)(C)OC(=O)N1CCC2CCC(=O)CC2C1 +Cc1ccccc1-c1cnc(NC(=O)Nc2c(C)n[nH]c2C)s1 +Cc1ccc(CCC(=O)NC2CCCN(c3ccccc3F)C2=O)o1 +Fc1ccccc1CN1CCCC1c1nnc2ccccn12 +CN(C)C(=O)c1cccc(-c2ccc(O)c(F)c2)c1 +Cc1nccn1Cc1ccc(NC(=O)C2CC3C=CC2C3)cc1 +Cc1nc(CN2CCOC(c3nccs3)C2)oc1C +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)C1CC=CC1 +Cn1cc(NC(=O)C2CCOCC2)cc(Br)c1=O +COc1ccc(CN(C)C(=O)CSc2ccc(F)cc2)c(OC)c1 +Cc1cccc(COC(=O)c2cc(S(N)(=O)=O)ccc2C)c1 +Cn1cc(C2CN(Cc3ccc(-c4ccccc4)o3)CCO2)cn1 +COc1ncccc1N(C)C(=O)c1cccc(-c2ccccn2)c1C +CCOc1ccccc1NCC(O)c1cccc(OC)c1 +CCOc1ccccc1C(=O)NCC(=O)N1CCc2ccccc2C1 +Cc1ccc(NC(=O)c2nccnc2N)cc1S(C)(=O)=O +Cn1c(SCc2cc(-c3ccco3)on2)nnc1-c1cccnc1 +CN(C)C(=O)COc1cccc(NC(=O)c2cccc(Cl)c2)c1 +O=C(NC(CCO)c1ccccc1)c1ccc2cccc(F)c2n1 +COc1cccc(-c2noc(-c3ccc[nH]c3=O)n2)c1 +COC(=O)c1ccc(-n2nnc(CO)c2C2CCC2)cc1 +COC(=O)CCC(O)c1c(C)cc(OC)cc1C +O=C1CSc2ccc(C(=O)OCC3CC3(Cl)Cl)cc2N1 +O=c1cc(CSc2ncn[nH]2)nc2ccc(Cl)cn12 +CCN(CC)C(=O)CSc1nc(-c2cccs2)n[nH]1 +CCOC(=O)CCC(C)NC(=O)c1sc2ccc(F)cc2c1C +Cc1ccc(OCC(=O)OCc2ccn(C)c(=O)c2)cc1C +COc1ccc(NC(=O)N(C)Cc2ccc(C)s2)cc1NC(C)=O +Cc1cc(C)n(CCc2nc(-c3cc4ccccc4o3)cs2)n1 +CCCc1cc(C(=O)N(C)Cc2csc(C(C)C)n2)no1 +CC(C)(C)Nc1ccc(C(=O)N2CCCC(Cn3ccnc3)C2)cn1 +N#Cc1ccc(OCc2noc(-c3cccs3)n2)cc1 +C#Cc1cccc(NCc2ccccc2OCC)c1 +N#Cc1ccc(Cl)cc1NCc1ccc2c(c1)OCO2 +O=S(=O)(Cc1ccccc1)N1CCC(c2nc(C3CC3)no2)C1 +Cn1cnc(CNC(=O)c2cccnc2OCC(F)(F)F)n1 +CCOc1cc(CNC(=O)c2cccc(C)c2)ccc1OC +Cc1nc2c(-c3ccccc3F)csc2c(=O)[nH]1 +COCc1csc(NC(=O)NCc2cn(-c3ccccc3)nn2)n1 +Cc1ccc(=O)n(CC(=O)NC2CCCCC2OCCC(C)C)n1 +COc1ccc(-c2nc3sc(=Cc4cccnc4)c(=O)n3n2)cc1 +O=c1nc(NCc2ccc3c(c2)OCO3)[nH]nc1-c1ccccc1 +CCc1ccc(OCC(=O)NCCc2nc(C)cs2)cc1 +CCOC(=O)CN(CC(F)(F)F)C(=O)c1cnc(C)cn1 +CCOC(C)C(=O)Nc1cc(-c2cc(Cl)ccc2OC)n[nH]1 +Cc1ccc(CNC(=O)CSc2nnc(C)n2-n2cccc2)cc1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NC(C)(C)C +O=C(NCCC(F)(F)F)c1cccnc1OCC(F)F +Cc1ccc(C(=O)CCC(=O)Nc2nc(C)cs2)cc1 +CCn1nccc1CN(C)S(=O)(=O)c1ccc(C)cc1 +Cc1cc(C(=O)NCCCO)c2cnn(C(C)C)c2n1 +CN(CCOc1ccc(C#N)cc1)S(=O)(=O)c1cccs1 +CC(=O)Nc1cc(C(=O)COC(=O)c2cccc(Cl)c2)ccc1O +COC(=O)Cc1csc(NC(=O)c2cc(C)n(C3CC3)c2C)n1 +COCC(O)COc1cc(Cl)c(Cl)cc1Cl +COc1cc(C)c(C(=O)Nc2nc(C(C)=O)cs2)cc1OC +O=C1OC(COc2ccc(F)cc2)CN2Cc3ccccc3CC12 +CCCCc1nnc(NC(=O)Cc2ccc(C)s2)s1 +COC(=O)c1noc(N)c1-c1ccc(OC)cc1OC +CC(C)(C)N(CCO)S(=O)(=O)c1ccc(F)cc1 +CC(C)(C)C(=O)NCC1(c2cccs2)CCOCC1 +Cn1cnn(-c2ccc(NCCc3cccs3)cc2)c1=O +Cn1cccc1C(=O)N1CCC(c2nc(-c3ccccc3)no2)CC1 +COc1ccc(C(=O)OCC(=O)c2ccccc2Cl)cc1N +Cc1nc(CCCNC(=O)c2c(F)cccc2Br)n[nH]1 +Cc1ccc(F)c(NC(=O)CCCNC(=O)c2ccccc2)c1 +O=C(NCCN1CCc2ccccc21)c1ccc(-n2cnnc2)nc1 +CCCc1nc(Cn2cnc(C(=O)OC)n2)cs1 +COc1ccc(C(O)C(C)NC(=O)c2ccc3nccnc3c2)cc1 +N#Cc1cc(NC(=O)NCCc2cn3ccccc3n2)ccc1F +CC(CNC(=O)NCc1ncn(C)n1)Oc1ccccc1 +O=C(NCCOc1cccc(Br)c1)Nc1nncs1 +CCOc1nn(CC)cc1C(=O)N1CCC(C(=O)OC)CC1 +COc1ccccc1CNC(=O)CSc1nnc(C(C)(C)C)n1N +CC(C(=O)NC1(c2ccc(F)cc2F)CCOCC1)C1CC1 +O=C(NCCCCN1CCOCC1)c1ccc(F)cc1F +c1ccc(-n2ncc(CNCCc3ccc4c(c3)OCO4)n2)cc1 +CCC(CNC(=O)Nc1cnn(CC(N)=O)c1)c1ccccc1 +CC(C)(C)C(=O)NCCC(=O)Nc1cc(C#N)ccc1Cl +CCCNC(=O)C(N)c1ccc(OC)cc1OCC +Cc1nc(NC(=O)CN2C(=O)CC(C)(C)c3ccccc32)sc1C +COCCN(CC(F)F)C(=O)Cc1c[nH]c2c(C)cccc12 +CC(NC(=O)NCc1ncn(C)n1)c1cccc(-n2cccn2)c1 +O=C(COCC1CC1)NCc1ccc(N2CCCCC2=O)cc1 +CN1CCN(C(=O)C2CC2c2ccccc2Br)CC1 +O=C(NC1CC1)c1cccc(NS(=O)(=O)c2cccc(F)c2)c1 +CCN(C(=O)Cn1nc(C)c2ccccc2c1=O)c1ccccc1 +CC(=O)N1CCN(C(=O)CN2CCN(c3ccccc3O)CC2)CC1 +O=C(Nc1ccn(Cc2ccncc2)n1)c1ccc(O)c(Cl)c1 +CC1CCC(NC(=O)COc2ncnc3sc4c(c23)CCC4)CC1 +COc1cc(CO)c(O)c(Cc2cc(OC)cc(CO)c2O)c1 +Cc1cc(C(=O)N2CCC(C)CC2)c2c(C)noc2n1 +CN(CCc1ccccn1)C(=O)CNC(=O)N(C)CC1CCCC1 +Fc1cc(Cl)c2c(c1)CCNC2c1cc[nH]c1 +CC(C)(C)C(=O)N1CCN(C(=O)Nc2ccc(C#N)c(Cl)c2)CC1 +CCc1nnc(CN(C)c2ccc3cc[nH]c3n2)o1 +CC(=O)Oc1ccc2c(=O)c(-c3ccccc3)coc2c1 +CC(C)(C)C(O)CCNC(=O)C1c2ccccc2Oc2ccccc21 +O=C(N1CCC(O)C1)C1(c2ccc(F)cc2F)CCCC1 +Cc1c(C(=O)N(C)Cc2ccccc2)cnn1-c1ccc(F)cc1 +Cc1ccc(S(=O)(=O)N(CCO)CC(C)C)s1 +Cc1ccc(-c2c(C#N)nnn2-c2ccc(F)cc2)cc1 +CC(O)c1ccccc1OCC(=O)NC(C)C(C)C +CCOC(=O)c1c(C)oc2ncn(Cc3cccc(F)c3)c(=O)c12 +CCC(NC(=O)c1ccc(NC(=O)C2CC2)cc1)c1ccc(C)cc1 +CCNC(=O)NCCNc1nc2ccccc2s1 +O=C(Nc1nc(C(F)(F)F)cs1)C1CC1c1ccco1 +C=CCNC(=O)c1cccc(N(C)S(C)(=O)=O)c1 +O=C(NCc1cccc(NC(=O)NC2CC2)c1)Nc1cccnc1 +CSc1ccc(NC(=O)NC(C)(C)CO)cc1Cl +Cn1c(N)c(Sc2nnnn2-c2ccccc2)c(=O)[nH]c1=O +COc1cccc(-c2nsc(NC(=O)c3cnc(C)cn3)n2)c1 +CCCOC(=O)C(CC)N1C(=O)CNc2cc(F)ccc21 +Cc1ccccc1Cn1c(C(=O)NCc2ccncc2)cc2occc21 +COCCn1cc(NC(=O)c2ccc(-n3cccc3)cc2)ccc1=O +CCN1C(=O)c2ccc(C(=O)Nc3cccnc3)cc2S1(=O)=O +CC1CCc2nc(NC(=O)c3ccnc(-n4ccnc4)c3)sc2C1 +Cc1ccc(Nc2nc(NCc3cccnc3)nc3[nH]ncc23)cc1 +N#Cc1ccc(-c2noc(-c3ccc4c(c3)OCC(=O)N4)n2)nc1 +CCOc1ccc(C(=O)Nc2cc(OC)ccc2OC)cc1 +O=C(NCC1CCCO1)NC1c2ccccc2CC1O +CCc1nc(C)c(C(=O)N(C)Cc2nc(-c3ccccc3)no2)o1 +CC(C)c1nnc(NC(=O)CSc2nncs2)o1 +NC(=O)CC1CCN(C(=O)NCc2ccccc2-n2cccn2)CC1 +O=C(NCc1cn(-c2ccccc2)nn1)c1ccoc1 +CCOc1ccccc1NC(=O)C1CC(=O)N(C2CCCCC2)C1 +Cc1ccc(S(=O)(=O)NCc2cccc(C(N)=O)c2)cc1Cl +Cc1cc(C)cc(NC(=O)c2nnn(Cc3ccccc3)c2N)c1 +O=C1Cc2cc(S(=O)(=O)Nc3ccccc3)c(Cl)cc2N1 +COc1ccc(-c2cc(N)c(=O)[nH]n2)cc1C(C)C +CCC1CN(CC(=O)N2CCCCC2)c2cc(C(C)=O)ccc2O1 +COc1ccc(CNC(=O)c2ccc3c(c2)nc2n3CCCCC2)cc1 +COc1cc(OC)cc(-c2nc(C)c(N)c(C)n2)c1 +Cc1cc(NC(=O)C(C)c2cccs2)ccc1-n1cnnn1 +Cc1ccc(-c2nc(C(=O)OCC3CCC(=O)N3)cs2)o1 +Cc1nc(CCN(C)C(=O)C23CC4CC(C)(CC(C)(C4)C2)C3)no1 +CCNC(=O)NCCCOC(=O)c1cccc2ccccc12 +COc1ccc(C(=O)COC(=O)C2CCC(=O)N2)cc1 +COc1cccc(C2NC(=O)c3ccccc3N2C)c1OC(C)C +CC(C)c1ncc(CN2CCC3OCCCC3C2)s1 +CNS(=O)(=O)c1ccc(NC(=O)Cc2ccccc2Cl)cc1 +COC(=O)c1csc(-c2c(F)cccc2F)n1 +Cn1ncnc1C1CCN(C(=O)c2ccccc2Cl)CC1 +CCOC(=O)CN(C)S(=O)(=O)c1cc(Cl)cc(Cl)c1 +CS(=O)(=O)c1cccc2c1CCCN2C(=O)COc1ccccc1 +N#Cc1ccc(C(N)c2nnc(C(O)CO)o2)cc1 +CC(NC(=O)CCCc1cccs1)C(=O)Nc1ccccc1 +Cc1cccc(C)c1NC(=O)CSc1nnc(C2CC2)n1N +O=C(NCc1cn2ccccc2n1)N1CCCC1c1ccncc1 +CCOc1ccc(-n2nnc(C#N)c2-c2ccccc2)cc1 +N#CC(C(=O)c1ccccc1)c1ccc(C(F)(F)F)cn1 +O=C(Nc1ccc(F)cc1)C1CCN(C(=O)c2cccc(F)c2)CC1 +C=CCN(c1nc(C)nc2oc(C)nc12)C1CCCC1 +O=C(Cn1ncn2c(cc3ccccc32)c1=O)NCc1cccs1 +Cn1c(C(=O)Nc2ccccc2)nnc1-c1ccccn1 +O=C1CCc2cc(S(=O)(=O)Nc3ccc(F)c(F)c3)ccc2N1 +O=C(CNC(=O)c1n[nH]c(=O)[nH]1)NCC1CCCC1 +COC(CNC(=O)C1COc2ccccc2O1)c1ccc(C)s1 +CC(C)CCN(CC(C)CO)C(=O)c1ccc(N)cc1 +Cc1ccccc1N1CCCN(C(=O)COCC2CCCO2)CC1 +O=C(CCN1CCCCC1=O)NCc1cccc(-c2ccccc2)c1 +NC(=O)C1Cc2ccccc2N1C(=O)Nc1ccccc1F +CCn1c(=O)n(CC(O)c2ccc(F)cc2F)c2ccccc21 +CCC(OC(=O)c1c(C)nn2cccnc12)c1cccc(OC)c1 +CN(Cc1ccc(Br)cc1)C(=O)c1ccc(C#N)cn1 +COc1cccc(C(=O)Nc2cccc(S(N)(=O)=O)c2)c1F +CCOC(=O)CN(C)C(=O)c1cc(F)c(F)c(F)c1 +CC(C)c1cc(C(=O)N(C)Cc2cnc3ccccc3n2)on1 +CCOC(=O)C(C)(NCC1CC1)c1ccc(F)cc1F +COC(=O)c1cc(-c2cc(C)cc(Cl)c2OC)n[nH]1 +COc1cc(C(C)Nc2ccc(F)c(F)c2)ccc1O +Nc1c(Oc2ccccc2)ncnc1-n1nnc2ccccc21 +O=C(Cc1c[nH]c2ccccc12)Nc1cccnc1N1CCCC1 +CCOC(=O)CC(C)CNC(=O)c1cc(F)cc2[nH]cnc12 +Cc1ccc(C)c(C2CCN(C(=O)OC(C)(C)C)CC2=O)c1 +CN(C)c1ccc(C(=O)Nc2cccc(F)c2)cn1 +COc1ccc(NC(C)C(=O)Nc2sccc2C#N)cn1 +CCOc1ccc(NC(=O)C(C)CC(N)=O)cc1 +CN(C)c1ccc(-c2nnn(CC(=O)N3CCCCCC3)n2)cc1 +O=C(CCc1nc2ccccc2s1)NCc1ccc(O)cc1 +Cc1noc(CCCNC(=O)c2ccc(F)c(Br)c2)n1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3ncccc3C)cc2F)n1 +CCCC1CC(=O)N(Cc2ccnc3nc[nH]c23)C1 +CC(C#N)CN(C)C1=NS(=O)(=O)c2ccccc21 +COCCN1C(=O)CCC12CCC(NC(=O)Cc1ccccc1)CC2 +CS(=O)(=O)N1CCCC1CNC(=O)c1cccc(-c2ccoc2)c1 +COc1ccccc1C(NC(=O)c1ccsc1)c1nccn1C +CCCn1c(=O)n(CC(=O)Nc2cccc(OC)c2)c2ccccc21 +O=C(Nc1c[nH]cc(Br)c1=O)c1ccn2ccnc2c1 +NC(=O)CCN1C(=O)c2ccccc2C1c1c[nH]c2ccccc12 +Cc1cc(C)cc(C2Nc3ccccc3C(=O)N2C)c1 +O=C(CNc1ccc(-n2cccn2)cc1)NCc1ccco1 +Cc1ccc2nc(-c3ccncc3)cc(C(=O)N3CCC(C)CC3)c2c1 +Cc1ccc2c(ccn2CCC(=O)Nc2nncs2)c1 +O=c1c2sccc2ncn1CCSc1ncnc2ccsc12 +CCn1cc(CCNC(=O)Nc2ccccc2C)c2cccnc21 +O=C(Nc1ccc2c(c1)CCC2)c1cccc(NC(=O)C2CC2)c1 +CC(C)CC(=O)Nc1ccc2oc(-c3cccnc3)nc2c1 +Cc1ccccc1C(C#N)CC(=O)Nc1ccc(C#N)cc1 +Cc1nccc(CNC(=O)Cc2c(Cl)cccc2Cl)n1 +CCOC(=O)CNC(=O)c1ccc(NC(C)=O)cc1 +CCCCCC(C)NC(=O)c1sc(C)nc1C +O=C(Nc1ccc2c(c1)COC2)c1cccc2c1OCCO2 +COc1ccc(NC(=O)c2c(C)nc3sccn23)cc1 +NS(=O)(=O)NC(c1cccs1)C1CCCC1 +CCOC(=O)C1(NC(=O)CCn2cc(C)cn2)CCCCC1 +CS(=O)(=O)NCCNC(=O)c1cc(Cl)ccc1N +Cc1nc(CNC(=O)CN(C)c2ncnc3[nH]cnc23)cs1 +CCc1cc2c(C)cc(=O)oc2cc1OS(=O)(=O)c1cnn(C)c1 +CCC(Oc1ccccc1C)C(=O)Nc1ccon1 +CC1(C)CCCN1C(=O)c1cc(CN2CCOCC2)on1 +C=CCNC(=O)c1ccccc1SCc1cscn1 +CCCNC(=O)c1ccccc1NC(=O)c1ccccc1C +Cc1csc(CNc2cccc(C(=O)N3CCc4ccccc43)c2)n1 +O=C(Nc1ccc2c(c1)OCCO2)c1c[nH]c2ccccc12 +CC(C)Oc1cccc(-c2cc(CO)c(=O)[nH]n2)c1 +Cc1c(CNC(=O)Nc2ccc(CC(F)(F)F)cc2)cnn1C +CC(NS(C)(=O)=O)C(=O)Nc1nnc(C(F)(F)F)s1 +COCCNC(=O)c1ccc(CN2CC(=O)N3CCCC3C2=O)cc1 +CC(C)(C)C(=O)CNC(=O)c1ccc(Cn2cccn2)cc1 +CCOC(=O)c1cccnc1NC(C)C(=O)NC +CCCn1nnc(NC(=O)COc2cc(C)cc(C)c2)n1 +CC(C)(C)NC(=O)c1ccc(NC(=O)Cc2cccs2)cc1 +O=C(c1ccc(N2CCCC2=O)cc1)N1CCCC1 +N#CCc1ccc(NC(=O)CCC(=O)c2ccc3c(c2)CCC3)cc1 +CCN(Cc1cc(=O)[nH]c2ccccc12)C(=O)c1ccc(Cl)cc1 +Cc1ccc(C(NC(=O)COc2ccccc2O)C2CC2)cc1 +CCS(=O)(=O)c1ccc(O)c(Nc2nc(C)ccc2N)c1 +Cc1ccc(OCc2c(C#N)nnn2-c2ccc(O)cc2)cc1 +Cc1cc(C)nc(Nc2nc(CC(=O)NC3CC3)cs2)n1 +COc1ccnc(NC(=O)c2ccc(F)cc2OC(F)F)c1 +CS(=O)(=O)N1CCN(C(=O)NCc2ccccc2F)CC1 +C=CCN1C(=O)C(C)Oc2ccc(C(=O)C(C)N)cc21 +O=C(CC(c1ccccc1)C(F)(F)F)Oc1ccccc1 +CC(NS(=O)(=O)N1CCC(C(C)(C)C)CC1)C1CCOCC1 +O=C(OCc1cccs1)c1ccc2c(c1)CCN2 +O=C1COc2cc(C(=O)NCCc3cccc4ccccc34)ccc2N1 +CCOc1c(OC)ccc2c1C(Cn1cnnn1)NCC2 +O=C1CC(c2ccccc2F)c2ncn(-c3ccccc3)c2N1 +COC(=O)C1C2C=CC(C3CC23)C1C(=O)OCC(=O)c1ccccc1 +CCC(=O)N1CCC(C(=O)Nc2ccccc2CC)CC1 +CCCNC(=O)COc1ccc(S(=O)(=O)N2CCCCC2)cc1 +Cc1ccc(-c2nnn(Cc3cc(=O)n4ccsc4n3)n2)cc1 +COCCCNC(=O)NC(C)Cc1ccc(O)cc1 +CC(=O)Nc1cccc(-c2nc3cc(CO)ccn3c2N)c1 +CCCn1c(CCC(=O)Nc2cccc(F)c2)nc2cccnc21 +CCCCNC(=O)CCn1cnc2c([nH]c3ccc(F)cc32)c1=O +NC(=O)COc1cccc(C(=O)NCC2CCOC2)c1 +CCN(CC1CCCO1)C(=O)c1coc(CN2CCOCC2)c1 +CCc1ccccc1NC(=O)N(C)Cc1csc(C)n1 +CCOC(=O)NCCNC(=O)Nc1cc(S(C)(=O)=O)ccc1C +Cc1ccc(-c2nnn(CC(=O)Nc3c(C)cccc3C)n2)o1 +COc1c2c(c(S(N)(=O)=O)c3c1OCO3)CCN(C)C2 +CC(C)OC(=O)Cn1cnc2c(Cl)cc(Cl)cc2c1=O +CCOc1ccc(-c2nnc(NC(=O)CC)o2)cc1OCC +CCCN1CCN(C(=O)Cn2c(=O)cnc3ccccc32)CC1 +CC(Cc1ccco1)NC(=O)Nc1ccc(N2CCNC(=O)C2)nc1 +Fc1cccc(NCc2ccc3c(c2)OCO3)c1F +CCCCOC(C)C(=O)N1CCC(C(N)=O)c2ccccc21 +Cc1nc(SCC(=O)N2CC(C)CC(C)C2)c2ccccc2n1 +CCN1C(=O)C(c2ccccc2)Oc2c(OC)cc(CO)cc21 +COC(=O)Cc1csc(NC(=O)Cc2cccc(OC)c2)n1 +O=C(NCC(=O)N1CCN(c2ncccn2)CC1)c1ccco1 +NC(=O)c1ccsc1NC(=O)CSc1nnc(C2=NC=CC2)o1 +CC(=O)NCC1CCN(C(=O)CC(C)C2CCCCC2)CC1 +Cc1ccc(OCC(=O)NCCc2nnc3n2CCCCC3)c(C)c1 +CCCn1c(SCC(C)O)nc2c1c(=O)[nH]c(=O)n2C +COC(=O)C1CC(O)CN1Cc1ccn(-c2ccc(F)cc2)n1 +COCCOCC1NCCc2c(Cl)cccc21 +O=C(Cn1cnnn1)NCc1ccc(Cl)cc1Cl +CCN(Cc1noc(C)n1)C(=O)c1cc(C)nc2cc(F)ccc12 +CC(Sc1ccccn1)C(=O)NCC(=O)N1CCc2ccccc21 +COc1ccc2oc(C(=O)NCCNC(=O)C3CC3)c(C)c2c1 +O=C(c1ccncc1)N1CC2c3ccccc3C(N3CCOCC3)C2C1 +C=C(C)CN(CC)C(=O)c1ccc(Cl)cc1N1CCCC1=O +COC(=O)c1occc1Cn1nc(-c2ccccc2F)ccc1=O +Cc1n[nH]c(SCC(=O)N(C)C2CCCCC2C)n1 +Cc1nc2cc(C(=O)C3CCCCN3)ccc2n1C1CC1 +CCOC(=O)C1CC(=O)N(c2ccccc2Br)C1 +Nc1cc(-c2ccc(=O)[nH]n2)ccc1N1CCCCCC1 +CC(=O)c1ccc(OC(=O)CCc2nc(-c3cccnc3)no2)cc1 +CCOCCC1(CNC(=O)C2CCCO2)CCC1 +N#Cc1cccc(CS(=O)(=O)N2CCCCC2c2ccco2)c1 +Cc1ccc2c(c1)c(=O)c(C#N)cn2CC(=O)OC(C)C +CN1C(Cl)=NS(=O)(=O)c2cc(Cl)ccc21 +O=C(c1ccncc1)N1CCC2(CC1)C(=O)Nc1ccccc12 +COC(=O)c1cc(CN2CCOC(c3cccs3)C2)c[nH]1 +CCn1nccc1C(=O)NCCc1cn(C)c2ncccc12 +CC(NC(N)=O)C(=O)Nc1ccc(N(C)C(C)C)c(F)c1 +Cc1ccc(OCC(=O)Nc2cccc(O)c2)cc1C +CC(C)N(C)S(=O)(=O)N1CCN(Cc2ccccn2)CC1 +COc1ccc(S(=O)(=O)NCc2cn3ccsc3n2)cc1C +Cc1ccc(F)cc1C(=O)N(C(C)C)C1CCOCC1 +Cc1cc(C(=O)NC(C)c2cccc(N3CCCC3)c2)on1 +C=CCOC(=O)c1ccc(-c2cccc(N)c2C)o1 +CC1(C)Cc2cc(CN(CCCO)CC(F)(F)F)ccc2O1 +O=C(NCCCN1CCCC1=O)c1cn2ccccc2n1 +Cc1noc(C)c1CN(C)C(=O)NC(Cc1ccccc1)C1CC1 +Cc1oc(C(=O)N(C)Cc2ccccc2)cc1S(N)(=O)=O +Cc1cccc(C)c1OCC(=O)Nc1ccc(Cl)cc1C(N)=O +CCC(CO)NS(=O)(=O)c1c(C)ccc(N)c1C +CC1CCC(NC(=O)N2CCC3(C2)OCCO3)C(C)C1 +CCSc1cc(C(=O)N2CC(C)c3ccccc32)ccn1 +Cc1cnc(C(=O)OCC(=O)Nc2ccc(C(C)C)cc2)cn1 +CCC(=O)NCCCc1nc2ccccc2n1CC(C)C +Cc1cc(C(=O)N(CC2CCCO2)c2ccncc2)c(C)n1C(C)C +CC1CCCN(C(=O)C2CCN(C(=O)Nc3cccc(F)c3)CC2)C1 +COc1ccc2nc(-c3ccc(C)c(N)c3)[nH]c2c1 +Cc1cc(C(=O)Nc2nc3cc(F)c(F)cc3s2)on1 +COC(=O)c1cnn(-c2nc3ccccc3[nH]2)c1C +CCCNC(=O)COc1cc(O)c2c(c1)OC(C)(C)CC2=O +COc1ccccc1C(=O)OCC(=O)NCC(F)(F)F +Cc1ccc(NC(=O)C23CCC(C)(C(=O)O2)C3(C)C)cc1 +COc1ccc2c(=O)cc(C(=O)NCc3ccccc3Cl)oc2c1 +Cc1n[nH]c(C)c1C(C)C(=O)Nc1cnn(-c2ccccc2Cl)c1 +Cc1cnn(C2CN(Cc3nc4c(c(=O)[nH]c(=O)n4C)n3C)C2)c1 +CCN(c1cccc(C)c1)S(=O)(=O)c1ccc(NC(C)=O)cc1 +Cc1cc(Cl)ccc1NC(=O)CS(=O)(=O)c1ccccc1F +COC(=O)C1CN(C(=O)NCc2ccccn2)c2ccccc21 +O=C(NCCc1ccccn1)c1ccn(-c2ccccc2Cl)n1 +Cc1ccc2nccc(NC(=O)c3ccncc3)c2c1 +CS(=O)(=O)N1CCCC1C(=O)N1CCCCC1 +CCOC(=O)c1cc(C)nc(S(C)(=O)=O)c1C#N +CN1C(=O)CCc2cc(C(=O)N3CCC(O)CC3)ccc21 +Cc1oc(-c2ccccc2Cl)cc1C(=O)NCCc1ccccn1 +COc1ccc(F)cc1-c1c(C(F)(F)F)nn(C)c1N +O=C(Nc1cccc2c1CCCC2)c1ccc2[nH]nnc2c1 +O=C(CCc1ccsc1)OCC(=O)N1CCCc2ccccc21 +Cc1cc(Cl)c(S(=O)(=O)NC2CCCC2)cc1OCC(N)=O +COc1cc(F)ccc1NC(=O)N(Cc1ccccc1)CC(C)O +CCn1c(NC(=O)c2ccc3ccccc3n2)nc2ccccc21 +NC(=O)c1ccc(-c2nc(COC(=O)C3CCC3)cs2)cc1 +CNC(=O)c1ccc(Cl)cc1NC(=O)c1ccccn1 +CC(=O)N(CCc1ccccc1)CC(=O)NC(C)c1nc(C)cs1 +COc1ccc(CCCCNC(=O)NC2CCCc3cn[nH]c32)cc1 +Cc1nc(C)c(C(C)NC(=O)Nc2ccncc2)s1 +COC(C)(C)CNS(=O)(=O)c1c(C)nn(CC(C)C)c1C +Cc1noc(C)c1CC(=O)N1CCN(Cc2cccc(Cl)c2)CC1 +Cn1c(CN2CCOCC2)nnc1C1CCCN(C(=O)C(C)(C)C)C1 +Cc1ccc(C)c(NC(=O)CC(C)n2cccn2)c1 +COC(=O)C(C)NC(=O)C1CNCc2cc(Cl)ccc21 +CCC(OC)C(=O)Nc1cccnc1N1CCOCC1 +c1ccc2c(CNCCc3nnc4n3CCCCC4)cccc2c1 +O=C(c1ccncc1)N1CCN2CC(OCc3ccccc3)CC2C1 +CCN1C(=O)c2ccccc2NC12CCN(C(=O)C1CC1)CC2 +CCC(NC(=O)CNC(=O)c1ccc(C)s1)c1ccc(OC)cc1 +O=C(CCCc1cc(F)ccc1F)Oc1ccc(-n2cnnn2)cc1 +O=C(NCc1cccc(O)c1)c1c(F)cccc1F +CC(C)C(O)CC(=O)Nc1ccc(O)c(Cl)c1 +CCNC(=O)CN(CC)C(=O)Cn1c(=O)oc2ccccc21 +COC(C(=O)Nc1ccon1)(c1ccccc1)c1ccccc1 +Cc1cccc(C(=O)NCCC(=O)N2CCCC2c2ccccc2)c1 +Cn1c(CNC(=O)c2ccco2)nc2ccccc21 +CC(C)Cc1nc(NC(=O)c2n[nH]c3ccccc23)n[nH]1 +COc1ccc(Cc2nccn2Cc2ccccc2C#N)cc1 +Cc1ccnc(NC(=O)CCc2ccc(S(N)(=O)=O)cc2)c1 +Cc1nc(CN2CCN(c3nc(C)c(CC(C)C)c(C)n3)CC2)no1 +COc1cc2ccccc2cc1C(=O)Nc1nc[nH]n1 +Cc1cc(CNC(=O)c2cc(=O)c3cccc(F)c3[nH]2)n(C)n1 +CC(C)c1cc(=O)n(CC(=O)Nc2cccc(F)c2)cn1 +COCCn1nc(C)c(CNC(=O)C2CC2c2ccc(C)s2)c1C +Cc1n[nH]c(C)c1CCC(=O)Nc1ccc2c(c1)nc(C(C)C)n2C +COC1CCC2OCCN(C(=O)c3c(C)cc(C)cc3C)C2C1 +COc1cccc2c1N(CC(=O)NC1CCN(C(C)=O)CC1)CCC2 +CCOc1ncccc1C(=O)Nc1cc2c(cc1Cl)OCO2 +Cc1nn(CCC#N)c(C)c1CCC(=O)N(C)Cc1ccc(O)cc1 +Cc1noc(C)c1CC(=O)N=c1[nH]c2ccccc2n1C(C)(C)C +CCCn1cc(NC(=O)c2cc(C(C)=O)c[nH]2)ccc1=O +CN(C)C(=O)c1cc(NC(=O)c2cccc(Cl)c2)ccn1 +N#CCCN(Cc1cc(C#N)ccc1F)C1CCOCC1 +CC(C)(CO)NC(=O)COc1ccc(Cl)c(Cl)c1 +Cc1ccc(C(C)NC(=O)c2ccc3c(c2)OCCO3)o1 +CCCC(=O)Nc1cccc(NC(=O)C(C)OCC)c1C +CCCN(C)C(=O)Nc1ccc(CC(=O)N(C)C)cc1 +O=C(Cn1cccn1)N1CCc2cc(F)ccc2C1 +CCOC(=O)C(NC(C)=O)(Nc1ccc(C)cc1C)C(F)(F)F +COc1cc(NC(=O)NCc2ccncc2)ccc1N1CCCC1=O +Cc1ccc(S(=O)(=O)NC(C)c2ncon2)cc1N(C)C +CS(=O)(=O)NCC1CCN(S(=O)(=O)C2CC2)CC1 +C=CCn1nnnc1SCCC(=O)Nc1ccccc1 +O=C(Nc1cnn(CC(F)F)c1)c1cccnc1OCC(F)F +Cc1ccc(OCc2cccc(NC(=O)OC(C)(C)C)c2)cn1 +O=C(NCCCN1CCCCCC1=O)c1cc2ccccc2c(=O)[nH]1 +N#CC(CN1CCOCC1)c1ccc(Br)cc1 +CN(Cc1ccccn1)C(=O)CC1C(=O)NCCN1Cc1ccoc1 +COc1cc(C#N)cc(Cl)c1OCc1ccc(C(N)=O)cc1 +Cc1cc(C)c(C(=O)NC2CCCc3occc32)c(C)c1 +NC(=O)Cc1nc2scc(-c3ccccc3)c2c(=O)[nH]1 +O=c1c2cc(OCc3ccccc3)ccc2nc2n1CCC2 +CCC(Cc1ccc(Cl)cc1Cl)NC(=O)c1n[nH]c(=O)[nH]1 +CCCCC(=O)c1ccc(NS(=O)(=O)CC)cc1 +CCOC(=O)C1CCN(c2ccnc(C(=O)N(C)C)c2)CC1 +COc1cc(C)c(C)cc1C(=O)CNC(=O)C(C)(C)C +CCN(C(=O)CSc1nnc(-c2ccc[nH]2)o1)C1=CCCC1 +CCCc1n[nH]c(C2CN(C(=O)c3cc(OC)ccn3)CCO2)n1 +Cc1cc(C(=O)CN(C)Cc2nc3ccccc3c(=O)[nH]2)c(C)[nH]1 +CN1CCN(C(=O)c2cc(C3CC3)on2)C(c2ccccc2)C1 +Cc1ccc(CC(=O)Nc2ccc(S(=O)(=O)N3CCCC3)cc2)o1 +CC(=O)Nc1ccc(NC(=O)c2cc3ccccc3c(=O)s2)cc1 +CN1C(=O)CC(C(=O)NCC2CC2)C1c1cccc(F)c1 +CCC(=O)Nc1ccc(-c2nnc(C(C)(C)C)o2)cc1 +CCn1c(Cc2ccccc2)nnc1SCCc1ccccn1 +Cc1ccc(-c2ncncc2Br)c(C)c1 +COC(=O)c1cnn2c(-c3ccccn3)ccnc12 +Cc1csc2nc(CSc3nnc(C4CC4)o3)cc(=O)n12 +CCNC(=O)CN(C)C(=O)c1cccc2c1OCCO2 +C1CCC(c2nc(CN3CCOCC3C3CC3)no2)CC1 +Cc1ccccc1NC(=O)C(C)n1nc(C)c2c(C)onc2c1=O +Cc1cc(NC(=O)Cc2c(C)nn(C)c2C)n(C)n1 +Cc1nc(-c2ccc(CC(=O)N3C(C)COCC3C)cc2)cs1 +CC1CCC(NC(=O)Nc2ccnc(C(=O)N(C)C)c2)CC1 +Cc1cccc(C(=O)N(C)Cc2nc3ccccc3s2)c1C +NC(=O)c1csc(CN2CCC(Oc3cccc(Cl)c3)C2)c1 +Cc1nn(CC(=O)N2CCC3(CC2)OCCO3)c(=O)c2noc(C)c12 +CCOCCN1CCN(C(=O)c2cccc(OC)c2OC)CC1 +CCOCCCNC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +COCCCNC(=O)C(N)c1ccc2c(c1)OCO2 +COc1ccccc1-c1nc2ccccc2nc1C#N +Cc1ccccc1C(=O)NCC#Cc1ccc(C(=O)N(C)C)cc1 +COc1cccc(CCNCc2nc3c(s2)CCCC3)c1 +O=C(Nc1ccccc1)Nc1cccc(OCCO)c1 +CCC(CC)N(C)C(=O)c1cc(OC)c(OC)cc1C +O=C(Cc1cn2ccsc2n1)Nc1cccc(CO)c1 +Cc1ncsc1C(=O)N1CCCC1c1cnn(C)c1 +Cc1cc(N)n(-c2cc(C)c3cccc(C)c3n2)n1 +CC(C1CC1)N(Cc1ccccc1)S(N)(=O)=O +O=C(C1CC1)N1CCN(Cc2ccc(F)cc2)CC1 +CCN(CC)C(=O)CS(=O)(=O)c1ccc(Cl)cc1 +O=C(NCC(=O)N1CCc2ccccc21)c1cccc(-c2ccoc2)c1 +CC(=O)c1ccc(SCC(=O)c2cccs2)cc1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(C(N)=O)cn1C +CCC(=O)Nc1nc(-c2ccc(CNC(C)=O)s2)c(C)s1 +O=C(CNc1nccc(C(F)(F)F)n1)NCc1ccco1 +Cn1c(SCCc2nc3ccccc3c(=O)[nH]2)nc2ccccc21 +CSc1nccn1-c1ccc(C(=O)Nn2cnc3ccccc32)cc1 +COCC(=O)NCCN1CCN(C(=O)c2ccsc2)CC1 +Cc1c(CC#N)cnn1-c1cccc(C(F)(F)F)c1 +Cc1ccc(C2CCCN2C(=O)C(C)Sc2ccccn2)s1 +CC=Cc1cc(C(=O)NCC(C)C)cc(OC)c1OC +CCC(=O)NCc1ccc(OCc2ccccc2)c(OC)c1 +CSc1ccc(NC(=O)N(CC2CCC(=O)N2)C(C)C)cc1 +NC(=O)c1csc(C(=O)Nc2ccc(Nc3ccccc3)cc2)c1 +N#CC1(NS(=O)(=O)c2cccs2)CCCC1 +O=C(c1c[nH]c2ccc(Br)cc12)C1COCCO1 +CN(Cc1ccco1)C(=O)c1cc2c(F)cccc2n1C +CS(=O)(=O)c1ccc(F)c(C(=O)NC2CCCC2)c1F +CNC(=O)NCC(=O)Nc1ccn(-c2ccccc2)n1 +O=C(NCCc1c[nH]c2ccccc12)c1ccc2nnnn2c1 +Cc1nc(COc2ccccc2C(=O)NC2CC2)no1 +N#Cc1ccc(COC(=O)c2cc(Cl)c[nH]2)cc1 +Cc1cc(=O)[nH]c(N2CCN(c3cccc(C)c3C)CC2)n1 +OC(COc1ccc(F)cc1)Cn1cnc2ccccc21 +COC(=O)c1ccc(Cl)c(Cn2c(-c3cccnc3)noc2=O)c1 +CC(C)CC1CCCN1C(=O)c1cc(N2CCCC2=O)ccc1Cl +CCSc1nnc(SCCc2ccncc2)s1 +CCCOC(=O)N1CCC(c2n[nH]c(=O)n2CC)CC1 +CCC(C(=O)OC)N1CCNc2cc(Cl)ccc21 +O=C(COC1CCCCC1)Nc1ccccc1N1CCCC1=O +Cc1cccn2c(CC(=O)NCc3ccc4c(c3)CC(C)O4)cnc12 +Cc1ccc(C(=O)NCC(=O)C(C#N)c2nc3ccccc3n2C)cc1 +Cc1cccc(-n2ccnc2SCC(=O)N2CCOCC2)c1C +CCc1nnc(NCc2nc(-c3ccccc3)n[nH]2)o1 +COc1cccc(-c2n[nH]c(C3CC3)c2NC(=O)c2cccs2)c1 +CCCOCC(=O)Nc1cc2ccccc2cc1C(=O)OC +CCNC(=O)CNC(=O)C1CCOc2ccccc21 +COc1ccccc1CC(=O)Nc1ccccc1N1CCOCC1 +CCOC(=O)CSc1nnnn1-c1c(C)cccc1C +Cc1cccc(S(=O)(=O)N2CCc3nocc3C2)c1 +O=C(CCCc1cccs1)NC1CCN(c2ncccn2)CC1 +COc1cccc2c1CCNC2CSc1ncccn1 +COC(=O)Cn1ccnc1Cc1ccccc1S(C)(=O)=O +NC(=O)C1CCCN(S(=O)(=O)c2ccccc2-c2ccccc2)C1 +CCN(CC(=O)Nc1c(F)cccc1F)C(C)=O +CC(Oc1ccc(C#N)cc1)C(=O)NC1CCCCC1C +CCn1ncc(-c2cccc(OC(C)C)c2)c(N)c1=O +COc1ccccc1C(=O)Nc1cnccc1-n1cc(C)cn1 +CC(C)C1CN(c2ncccc2Cl)CC1NS(C)(=O)=O +O=C(OC1CCOC1=O)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +COC(=O)c1ccc(NC(=O)CN2CCOc3ccc(F)cc32)cc1 +Cc1csc(N(C(=O)C2COc3ccc(F)cc3C2)C2CC2)n1 +O=C(C1CC1)N(Cc1ccc2cc[nH]c2c1)C1CC1 +CC(C)C1C(=O)NCCN1C(=O)c1cccc2ncccc12 +C#CCN1CCN(S(=O)(=O)c2ccc(Cl)c(Cl)c2)CC1 +COC(=O)c1nnsc1NC(=O)CCc1ccccc1 +O=S(=O)(CC(O)CSc1ccccc1)c1ccccc1 +COc1ccc(C(=O)NCC(O)C2CCCCC2)cc1 +COC(=O)C(C)n1ccnc1-c1ccc(OC)cc1 +Cc1ccc(C2(Cc3cccc(Br)c3)NC(N)=NC2=O)o1 +Cc1nn(C(C)(C)C)cc1C(C)Nc1ccc(N2CCCC2=O)cc1 +Cc1ccc2c(CC(=O)Nc3ccc4c(c3)OCCCO4)coc2c1 +Cc1cc(F)ccc1NC(=O)c1ccc(-n2cncn2)nc1 +CCOC(=O)CSc1ncc(-c2ccc(F)cc2)o1 +Cc1cc(NC(=O)C(C)N2CCN(c3ccccc3F)CC2)no1 +NC(=O)CSc1nc2ccc(F)cc2c2c1CCCC2 +Cc1noc(COc2ccc(NC(=O)c3cc(F)ccc3F)cc2)n1 +CCc1c(C)[nH]c2c(-c3ccccc3)c(C)nn2c1=O +COc1cc(C(=O)OCC(=O)NC2CCCC2)cc(Cl)c1OC +COCCNC(=O)Nc1cccn(Cc2ccccc2)c1=O +CCc1noc(CC)c1CNC(=O)NC1CCC(C)CC1C +CN(Cc1cccc(F)c1)C(=O)COc1ccc(C#N)cc1 +CNC(=O)CN1CCN(C(=O)CCc2c[nH]c3ccccc23)CC1 +O=c1[nH]cc(CCn2cc(C3CCOC3)nn2)c(=O)[nH]1 +Cn1cc(CNC(=O)c2cc3c(F)cccc3[nH]2)cn1 +Cc1ccc(C(=O)NCCOc2ccc(F)cc2)cc1 +CC(=O)c1cccc(NC(=O)Nc2sc3c(c2C#N)CCC3)c1 +CC1(C)OC(=O)C(c2nc3ccccc3[nH]2)C(=O)O1 +Cc1csc(NC(=O)COc2ccccc2N)n1 +NS(=O)(=O)c1cc(C(=O)NCCCNc2ccccc2)cs1 +O=C(CC1CCc2ccccc21)N1CCC(c2cc(=O)[nH]cn2)CC1 +Cc1cccc(NC(=O)c2cccc(S(=O)(=O)NC(C)C)c2)c1 +CN(Cc1ccccc1)C(=O)CSc1n[nH]c(N)n1 +C=CCNC(=O)c1ccccc1NC(=O)C(C)Sc1nncn1C +C=CCNC(=O)c1c(N)n(CC(C)C)c2nc3ccccc3nc12 +CCCCNC(=O)c1ccc(N(C)S(C)(=O)=O)cc1 +CC(Oc1ccccc1)C(=O)NCCc1ccoc1 +Cc1ccc(NCc2n[nH]c(CC(=O)NC(C)C)n2)cc1 +CC1c2ncc(CNC(=O)C3CC3)n2CCN1S(C)(=O)=O +Cc1cnccc1CN(C)Cc1nc(Cc2ccccc2F)no1 +CCOC(=O)Cc1csc(NC(=O)c2cn3cc(C)ccc3n2)n1 +CCc1nc2ccccc2n1CC(=O)Nc1cc[nH]n1 +Cc1cc(NC(=O)c2ccoc2)ccc1C#CCO +O=C(NC1CCc2c(O)cccc21)c1ccc(-c2ccco2)[nH]c1=O +CCN(CCC(=O)OC)C(=O)c1cccc(F)c1 +C=CCn1c(C)nnc1SCC(=O)N(C1=CCCCC1)C1CC1 +Cn1nc2n(c1=O)CCN(CC(=O)N1CCCCCC1)C2 +Cc1cc(Br)ccc1NCc1cccc(C(N)=O)c1 +CC(=O)c1ccc(OCC(=O)N2CCN(C(=O)C3CC3)CC2)cc1F +CCNC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1 +CCCCn1c(N)c(N(C)CCC#N)c(=O)[nH]c1=O +COc1c(C)cc(C)cc1-c1cc(CC#N)c(=O)n(C)n1 +CCN(C(=O)Cc1ccc2c(c1)OCO2)C(C)CCO +C#CCOc1ccc(NC(=O)c2cnn(CC)c2)cc1 +CC1CCCCC1N(C)C(=O)COc1cc(Cl)ccc1C(N)=O +COc1ccc(-n2cnnc2SCC(=O)NC2CCCC2)cn1 +CCN(CC(=O)NCc1ccc(F)cc1)C(=O)c1cnccn1 +Cc1cc(C(=O)NCCNc2ccc3ccccc3n2)on1 +Cc1cccc(NC(=O)c2cc(C)n(Cc3cccs3)c2C)n1 +Cc1nc(CCNC(=O)CC2CCCCC2)cs1 +O=C(CSc1ccc(F)cc1)NCc1ccc2c(c1)OCO2 +Cn1ncc2c(Oc3ccc(F)cc3Cl)ncnc21 +O=C(Cn1nnc(-c2ccccc2)n1)N=c1[nH]nc2ccccn12 +CNC(=O)c1cccc(CCNCc2cnc(C)n2-c2ccccc2)c1 +Cc1cc(C(=O)Nc2ccc(F)cn2)ccc1S(N)(=O)=O +CCCCc1ccc(-c2nc3c(=O)[nH]c(N)nc3[nH]2)cc1 +CC(C)(C)n1nc(C(=O)NCCc2ccco2)cc1C1CC1 +Cc1csc(NC(=O)Cc2ccccc2Cl)n1 +CCN(CC(F)(F)F)C(=O)C1CC(=O)N(CC(F)(F)F)C1 +CCc1ocnc1C(=O)N1CCCC(n2nc(C)nc2C)C1 +CCN(c1ccccc1)S(=O)(=O)c1ccc2c(c1)OCCO2 +CCc1nc(C(=O)N2CCC(OCc3ccccc3F)CC2)c[nH]1 +CCn1ncc(-c2ccc(Cl)c(Cl)c2)c(C#N)c1=O +Cc1ccc(Cl)cc1NC(=O)C(C)Sc1nccc(=O)[nH]1 +CC(C)n1cc(CN(C)C(=O)c2cn3cccnc3n2)cn1 +Cc1ccc(F)c(NC(=O)C2CCCN(C(N)=O)C2)c1 +CCC(CC)NC(=O)CSc1nnc2cc(C)nc(C)n12 +Brc1cc(CNc2cccnc2)cc2c1OCCO2 +CN(C)c1cccc(CNC(=O)Cc2ccc[nH]2)c1 +CCOC(=O)c1cc(C)sc1NC(=O)COc1ccccc1F +Cc1nn(C)c(C)c1C(=O)N(C)Cc1ccc(OC(F)(F)F)cc1 +COc1ccccc1CNC(=O)C1COC(=O)N1Cc1nccs1 +NC(=O)C1(c2cccc(Br)c2)CCOCC1 +CNc1snc(C)c1C(=O)Nc1cc(Cl)c(N)c(Cl)c1 +O=C(COc1ccc(Cl)c(Cl)c1)NC1(CCO)CCC1 +Cc1ccc(F)c(CN2CCOC(c3cccc(O)c3)C2)c1 +Cc1cccc(OCC(=O)Nc2cnn(C3CCOCC3)c2)c1 +OCC1CN(Cc2ccc(F)c(Cl)c2)CC1CN1CCOCC1 +O=C1CCN(C(=O)C2COc3ccccc3C2)CC1 +CCCCc1noc(C(C)N2CCN(CCO)CC2)n1 +Nc1cccc(-c2csc(CC(=O)c3cccs3)n2)c1 +CC1CCC(N(C)C(=O)CSc2nncn2C(C)C)CC1 +CCC(=O)N1c2ccccc2CC1C(=O)N1CCc2ccccc2C1 +Cc1nnc(SCC(=O)OC2CCCCC2)n1N +CC(C)OCCCn1cnc2c([nH]c3ccccc32)c1=O +CC(C)(C)CC(=O)N1CCN(CC(=O)N2CCc3ccccc32)CC1 +COc1ccc(C)cc1S(=O)(=O)N=c1cccc(CO)[nH]1 +Nc1c(Cl)ccn2c(CCOc3ccccc3)nnc12 +O=C(CCn1cncn1)NCc1ccccc1Cn1cccn1 +O=C(NCCCCNC(=O)c1ccc(F)cc1)c1ccc(F)cc1 +O=C1CC2c3c(cccc31)CCN2C(=O)c1ccccc1 +O=C(CCn1cncn1)Nc1ccc(-c2ccccc2)cn1 +CC(C(=O)Nc1c(F)cccc1F)n1nnc(-c2ccccc2)n1 +COc1ccccc1CNC(=O)COc1ccccc1F +CCc1nn2c(C#N)c(-c3cc(C)ccc3OC)nc2s1 +Cc1ccc(C(=O)N2CCCN(c3nc(C)cs3)CC2)cn1 +CCOc1cc(NC(=O)c2cccc(F)c2)c(OCC)cc1N +Cc1cc(Cl)ccc1-n1c(C)cc(C)c(C#N)c1=O +COCC(=O)N1CCc2sccc2C1c1ccccc1 +COCCNC(=O)C1CCN(C(=O)c2ccccc2)CC1 +CC(C)C(NC(=O)Cc1ccccc1)C(=O)N(C)CCC#N +CC(C)(C)c1nn(-c2ncccn2)c2c1C(=O)CCC2 +COC(=O)NCC(=O)NCc1cccc(C(F)(F)F)c1 +COc1cccc(C(=O)Nc2cc3c4c(c2)CCN4C(=O)CC3)c1 +Cc1noc(C)c1CN1CCN(C(=O)C2CC2c2ccco2)CC1 +O=C(c1ccsc1)N1CCC(OCC2CCOC2)CC1 +Cc1ccc(C)c(NC(=O)COC(=O)c2ccc3c(c2)OCCO3)c1 +Cc1nc2ccc(Nc3ncnc4c3cnn4C)cc2s1 +COc1ccc(NS(=O)(=O)c2ccc(C(=O)NC(C)C)cc2)cc1 +Cc1cc(C)n2nc(C(=O)N(C)CC(=O)N(C)C)nc2n1 +CCN(C(=O)NCc1nnc2ccccn12)C1CCCC1 +NC(=O)c1cnc(NC(=O)Cc2c(F)cccc2Cl)s1 +Cc1oc2ccc(O)cc2c1C(=O)NCCCc1ccccn1 +N#Cc1cc(F)c(C(=O)N2CCc3cc(F)ccc3C2)c(F)c1 +CCC(=O)N1CCN(c2ccc(C(C)=O)cc2F)CC1 +Cc1ccc2c(C(=O)N3CCC(C(N)=O)CC3)nccc2c1N +NC(=O)NCC(=O)NCc1noc(-c2ccsc2)n1 +O=C(Nc1nnc(C2CCCCC2)o1)c1ccc2c(c1)OCO2 +Cc1ccc(C(=O)OCC(=O)N2C(C)CCCC2C)cc1O +O=C(c1cc2ccccc2[nH]c1=O)N1CC2C3CCC(CC3)C2C1 +CN(Cc1cccc(Cl)c1)C(=O)c1ccc2c(c1)OCCO2 +COc1ccc(-c2nn3cc(N)nc3s2)c(Cl)c1 +Cc1cc(C(=O)NC2CCCc3nc(-c4cccnc4)ncc32)c(C)o1 +O=C(NC1CCN(c2ccccc2)CC1)c1ccc2cc[nH]c2c1 +CC1CC1c1ccc(CN2CCN(C(=O)c3ccccc3O)CC2)o1 +CCc1noc(CC)c1CC(=O)N(C)Cc1nc(C)cs1 +NC(=O)c1csc(C(=O)Nc2cccc(Br)c2)c1 +Nc1nc(-c2ccncc2)ncc1C(=O)N1CCCCCC1 +CCCC(=O)NCC(c1ccco1)S(=O)(=O)c1ccc(C)cc1 +Cc1noc(C2CCCN(C(=O)c3ccccc3)C2)n1 +CCNC(=O)CSc1nnc(-c2ccco2)n1C +CCn1nnc2cc(C(=O)N3CCCS3(=O)=O)ccc21 +O=C(CC1OCCN(CCO)C1=O)Nc1ccccc1 +O=C(Nc1cccc2cn[nH]c12)c1cc(Cl)cc2cccnc12 +Cn1cc(CCNC(=O)N2CCOCC2C2CC2)cn1 +COc1ccccc1OCCC(=O)NCc1nc2ccccc2s1 +CCC(CC)c1nnc(NC(=O)CCc2c(C)nc(C)[nH]c2=O)s1 +CCOc1ccc(CC(=O)Nc2ccccc2N(C)C)cc1 +Cc1cc(S(N)(=O)=O)sc1C(=O)NC1CCCC1 +COC(=O)c1ccc2ccn(Cc3nc(C)no3)c(=O)c2c1 +Cc1nn2c(-c3cccc(N)c3)nnc2c2ccccc12 +Cc1ccc(C(=O)NCc2ccc3c(c2)OCO3)c(C)c1 +CCCC(C)(NS(=O)(=O)c1ccccc1)C(=O)OC +Cc1cc(C)n(-c2cc(SCC(=O)NC3CCCC3)ncn2)n1 +CCOCCCNC(=O)c1ccc(O)c(Cl)c1 +Cn1nc(COCC2CC2)c2c1CN(c1cnccn1)CC2 +Fc1ccc2c(c1)N(Cc1nnc(-c3cccs3)o1)CCO2 +COc1cccc(C(O)CSc2n[nH]c(=O)n2C2CC2)c1 +CCOCC(=O)Nc1ccc2c(c1)CCC(=O)N2C +CC(C(=O)N1CCN(c2ccc(F)cc2)CC1)n1cncn1 +Cc1csc(CNC(=O)c2cc3c(C)nn(C)c3s2)n1 +CCCC(=O)Nc1ccc(C)n(CC(=O)N(C)C)c1=O +Cc1cc(CN(C)C(=O)c2ccc3[nH]nnc3c2)no1 +Cc1oc(C(=O)N2CCc3ccccc32)cc1S(N)(=O)=O +Cc1nc(NC(=O)NCc2cnc3ccccn23)nn1C +COC(=O)C(NS(=O)(=O)c1ccccc1Cl)C(C)C +COCC(=O)N1CCN(c2nc3c(cnn3C(C)(C)C)c(=O)[nH]2)CC1 +CN(Cc1ccc2c(c1)OCO2)C(=O)Cc1cccs1 +CCOC(=O)C=C1CCC(c2cc(O)ccc2O)=C1N1CCOCC1 +CCOc1cccc2c1C(C(O)c1ccc(O)cc1)NCC2 +c1ccc(-c2cc3c(NCc4cccnc4)ncnc3s2)cc1 +O=C(CCc1nc2ccccc2c(=O)[nH]1)NC(c1ccccc1)C1CC1 +Cc1n[nH]c(C2CCCN2C(=O)c2ccccc2OC(F)(F)F)n1 +CCn1cc(N)c(-c2ccc(Br)cc2)n1 +O=C(c1ccccc1)C1CCN(S(=O)(=O)N2CCOCC2)CC1 +CC(NC(=O)CCC(=O)Nc1nccs1)c1ccccc1Cl +CN(Cc1ccccc1)CC(O)c1ccc2c(c1)OCCCO2 +Nc1nc(NCc2ccco2)nc2c1C(=O)CC(c1ccccc1)C2 +COCCOc1ccc(NC(=O)c2ccc(N(C)C)nc2)cc1F +C=CCc1ccc(OS(=O)(=O)c2cccs2)c(OC)c1 +CCNC(=O)NC1CC(=O)N(CCc2cccc(Cl)c2)C1 +Cc1ccc(-c2noc(CCC(=O)N(C)CCC#N)n2)cc1F +C=CCc1ccccc1OCCN(C)C(=O)c1cnccc1C +CC(C)CC1(CNC(=O)C2CCCOC2)CCCC1 +COc1cc(F)c(C(C)NCc2nnc(C)s2)cc1OC +COCc1ccc(C(=O)Nc2cccc(Cl)c2OC)cc1 +O=C(c1cnccn1)N1CCC(c2nnc(-c3cccnc3)o2)C1 +Cc1ccc(-c2nc(CNC(=O)COc3ccccc3)no2)cc1 +CCCc1nc(C)c(C(=O)N2CCN(C(=O)N(C)C)CC2)s1 +C#CCNC(=O)Nc1ccnn1CCc1ccccc1 +CC1=C(c2ccccc2)C1C(=O)NCc1cnc(C)cn1 +Cc1cc(CNC(=O)c2ccnc3ccccc23)ccc1F +O=C(Nc1cccnc1)c1c(Cl)cccc1Cl +O=C(C1CN(Cc2ccccc2)CCO1)N1CCCc2ccccc21 +Cc1ccc(-c2csc(NC(=O)C3CCC(=O)NC3)n2)cc1C +CC(=Cc1ccccc1)c1nnc(-c2cccc(N)c2)o1 +CCC(C)NC(=O)Cn1ncn2c(cc3cc(F)ccc32)c1=O +Cc1ccc(F)cc1NC(=O)NC1C2CCC(C2)C1CO +CCCOc1ccc(C(=O)N2CC(C)OC(C)C2)cc1OCCC +CC(C)(C)NS(=O)(=O)c1cccc(NC(=O)c2cccs2)c1 +O=C(Cc1ccc[nH]1)NCCNS(=O)(=O)c1ccccc1 +CC(O)CNC(=O)C1CNCc2cc(Cl)ccc21 +CCC(NC(=O)c1cc(C(C)C)nn1C)c1cnn(C)c1 +CC(C)Cc1cc(C(=O)NCCSc2nccn2C)on1 +Cc1cccc(-c2c(CO)nnn2-c2nnc(C(C)C)s2)c1 +CCOCCOC(=O)c1ccc(Br)cc1 +O=C(NCC(O)c1cccc(OC(F)F)c1)C(O)c1ccccc1 +CC(=O)N1CC(=O)c2cccc(Br)c21 +O=C(CNC(=O)CNC(=O)c1ccco1)NCc1ccncc1 +CC(C)Oc1nnc(SCC(=O)N2CCc3ccccc3C2)s1 +CC(c1cccs1)N(C)C(=O)NCc1cc[nH]n1 +CCOC(C)c1noc(C2(c3ccccc3)CCC2)n1 +CCC1(O)CCN(C(=O)c2cccnc2OC)CC1O +CCNC(=O)NCC1(OC)C2CC3CC(C2)CC1C3 +CCn1cnnc1CNC(=O)c1ccccc1CCc1ccccc1 +Cc1cccc(C)c1NC(=O)CN1CCOCC1C1CC1 +C#CCC(OC(=O)CC1CCCC1)c1ccccn1 +c1nc(N2CCOCC2)ncc1CN1CCCC(c2cn[nH]c2)C1 +O=C(Cc1csc(-c2ccncc2)n1)N1CCNCC1 +O=C(Cn1ncc2c(=O)[nH]cnc21)Nc1cccc(Br)c1 +CC(C)C(NC(=O)NCc1cc[nH]n1)c1cccs1 +CCSc1nnc(NC(=O)C(NC(C)=O)C2CCCC2)s1 +Cc1cccc(CN2CCN(C(=O)c3occc3C)CC2CCO)n1 +O=C(NCCC(F)(F)F)Nc1ccc(F)cc1Cl +Nc1cnn(CCCCc2ccc3c(c2)ncn3C2CC2)c1 +Cc1cc(C)cc(C(=O)N2CC3CCC2CN(C(=O)C2CCC2)C3)c1 +Cn1c(=O)oc2cc(NC(=O)c3cc(Cl)c[nH]3)ccc21 +CCN1C(=O)C(c2ccccc2)Oc2ccc(N)nc21 +CCCOC(=O)c1cc(-c2ccc(N)cc2)nn1CCO +CC(=O)c1ccccc1NCC(=O)N1CCC(C)CC1 +COc1cc(CN2CCOC3(CCCC3)C2)cc2c1OCO2 +CCn1c(C(=O)NCC(C)(C)C)nc2ccccc21 +O=C(Cc1csc(COc2ccccc2)n1)NCc1ccccn1 +CCN(CC(C)(C)O)C(=O)NC(c1ccccn1)C(C)C +Cc1ccc(F)cc1NCC(=O)NCc1ccc(F)cc1 +CCCNC(=O)NC(C)COc1ccc(F)cc1F +CC(C)C(C)NC(=O)CNC(=O)c1ccc2c(c1)OCO2 +CCC(Sc1cccc(N)c1)C(=O)Nc1ccccc1 +CC(C)NC(=O)CNc1ccc(C(=O)N(C)C)cc1 +CC1CCCCN1S(=O)(=O)n1nc(N2CCCCC2)nc1N +CCOc1ncccc1-c1nc(-c2ccncc2)no1 +CNc1snc(C)c1C(=O)NCc1cccc(COC)c1 +O=C(c1ccccc1)c1ccc(Oc2ccc3nnnn3n2)cc1 +Cc1ccc(-n2cnnn2)cc1S(=O)(=O)N1CCc2ccccc21 +COC(C)c1cccc(NC(C)c2ccc(S(C)(=O)=O)cc2)c1 +COC(=O)c1ccc(CNC(=O)c2cscn2)cc1 +CC1CC1C(=O)N(Cc1ccco1)c1ccccn1 +O=C(Nc1nccs1)C1CCCN1C(=O)Cc1cccc(F)c1 +CCc1oc2ccccc2c1CN1CC2OCCN(C)C2C1 +CCCc1nn(CC(=O)NC(C)(C)C)c(=O)c2cc3ccsc3n12 +Cc1cn(S(=O)(=O)c2cc(Cl)ccc2Cl)cn1 +CC(C)c1cnc(-c2ccc(NC(=O)N(C)C(C)CC#N)cc2)o1 +O=C(NC1CCC(O)CC1)C1CNCc2ccccc21 +CC(=O)NCCc1ccc(-c2csc(C3CC3)n2)cc1F +CCOc1cc2c(cc1CNC(=O)c1ccc(F)cc1)OC(C)C2 +CCOc1ccc(-c2nnc(SCC(=O)N(C)C3CC3)n2N)cc1 +CS(=O)(=O)c1ccc(C(=O)NCc2nc3ccc(F)cc3[nH]2)cc1 +O=C(Nc1cc(C(=O)N2CCCCC2)ccc1Cl)C1CCC1 +COc1cc(C)sc1C(=O)NCc1cccc(Cl)c1 +COc1ccc(OC)c(C(C)(O)CNCc2cccnc2)c1 +CC1CCC(N(C)C(=O)c2cnc3c(cnn3C(C)C)c2)CC1 +Cn1ccc(-c2ncc3c(Br)ccn3n2)n1 +CCC(C)NC(=O)CNc1ccccc1C(F)(F)F +c1ccc(-c2nc(NCc3ccncc3)cc(-c3ccccn3)n2)cc1 +CCn1ccc(-c2ccc(Br)cc2)c(C#N)c1=O +Cc1ccc(NC(=O)c2cc(C(N)=O)cs2)cc1-n1cnnn1 +CN(C)C(=O)c1cccc(C(=O)N2CCN(c3ccccc3)CC2)c1 +Cc1cccc(NC(=O)CCC(=O)N=c2[nH]nc3ccccn23)c1 +CCOC(=O)c1cc(-c2ccc(Cl)c(Cl)c2)nn1CCO +COc1ccccc1CNC(=O)Nc1cnc2c(c1)c(C)nn2C +CC(=O)N1CCC2(CC1)Nc1ccccc1N(CCO)C2=O +N#CCCN(Cc1cccnc1)C(=O)c1ccccc1C(F)(F)F +CCCCCNC(=O)C(N)c1cccc(F)c1OC +COC(=O)CCC(=O)Nc1ccc2ccccc2c1 +CCN(CC)C(=O)c1ccccc1NC(=O)N(C)CCOC +O=C(CC1CCN(c2cccnn2)CC1)Nc1nncs1 +Cc1cc(C(=O)N2CC(C(=O)Nc3ncc(C)s3)C2)no1 +O=C(Nc1nc[nH]n1)c1sccc1-c1ccccc1 +Cc1ccccc1OCC(C)NC(=O)c1ccco1 +Cc1csc(CCNC(=O)COC2CCCC(C)C2)n1 +CN(CCO)c1ccc(C(=O)Cc2ccccc2)cc1 +Cc1nc(COc2ccc(C(=O)N3CCOCC3)cc2)cs1 +O=c1cc[nH]c(C2NCCc3cc4c(cc32)OCC4)c1 +CN(Cc1ccccn1)C(=O)NCc1ccncc1 +CCc1ccccc1CNC(=O)Nc1ccc(C(=O)NC)cc1 +O=C(NCc1cn(-c2ccccc2)nn1)c1cc2ccccc2s1 +Cc1ccc(-c2nc(C(=O)NCc3csc(=O)[nH]3)cs2)cc1 +O=c1[nH]nc(CSc2nnnn2CC2CCCO2)[nH]1 +NC(=O)Cc1csc(NC(=O)c2cccc(-c3ccoc3)c2)n1 +O=C(Cn1cnc2ccccc2c1=O)OCCCc1cccnc1 +Nc1nc(SCc2csc(-c3ccccc3)n2)n[nH]1 +COc1cccc(-c2nnn(CC(=O)NCCC3CCCCC3)n2)c1 +COc1ccc2c(CC(=O)Nc3ccnn3C3CCCC3)coc2c1 +COC(=O)NCC(=O)N1CCC(OCc2ccccc2)CC1 +Cc1noc(COC(=O)CC(c2ccccc2)c2ccccc2)n1 +CCCn1c(O)nnc1SCc1cn2ccccc2c1C#N +Cc1nc(-c2ccccc2)sc1-c1ccnn1C +CCCCC(=O)NCCS(=O)(=O)c1ccc(Cl)cc1 +CC(C)CNC(=O)CCC(O)c1ccc(F)cc1 +CC(=O)N1Cc2ccccc2CC1C(=O)NCC1(C)CCCC1 +CCOc1cc(N)cnc1NCCc1nc2ccccc2[nH]1 +CCc1nnc(NC(=O)N(C)Cc2ccc(OC(F)F)cc2)s1 +COCC(C)NC(=O)C1(c2cccs2)CCCCC1 +CCc1onc(C)c1NC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +CC1CN(C(=O)CCOCc2ccccc2)c2ccccc21 +CNC(=O)c1ccc(OC)c(NC(=O)c2cc(F)cc3[nH]cnc23)c1 +O=C1Nc2ccccc2SC1CC(=O)N1CCOC2CCCCC21 +CN(CC(=O)Nc1cccc(Cl)c1)C(=O)CC#N +CCNc1ccc(S(=O)(=O)N(C)C(C)CC#N)cn1 +COc1cc2nc(NC(C)=O)sc(=O)c2cc1OC +Cc1sc(=O)n(CC(=O)N(Cc2ccccc2)C2CC2)c1C +NC(=O)c1ccccc1NCC(=O)Nc1cc(F)ccc1F +Cc1ccc(CNC(=O)Nn2cnc3ccccc32)c(N(C)C)c1 +CCCCNC(=O)c1n[nH]c2c1CN(C(=O)OC(C)(C)C)CC2 +O=C(c1ccsc1)c1cc2c(cc1Br)OCCCO2 +CC(C)CNC(=O)C(NC(=O)c1cc2cccnn2n1)C(C)C +Cc1ccc(N)cc1NC(=O)c1cc2c(s1)CCCC2 +O=C(NCc1cc(C2CC2)n(C2CCCC2)n1)C1CCC1 +COc1ccccc1CNCCc1nc(-c2ccco2)cs1 +Cc1cc(C(=O)NCc2ccc(C)o2)nc(N2CCOCC2)n1 +Cc1cccc(CC(=O)Nn2cnc3c(cnn3C(C)(C)C)c2=O)c1 +CN1CC(C(=O)Nc2nnc(-c3ccccc3Cl)s2)CC1=O +CCn1cc(C(=O)Nc2cccc(C(=O)N3CCCC3)c2C)cn1 +CC(C)n1nnnc1SCc1nc2cc(Cl)ccc2c(=O)[nH]1 +CC(c1cccs1)N(C)C(=O)NCc1ncn(C)n1 +Cc1cc(NC(=O)CNc2cc(S(C)(=O)=O)ccc2F)n(C)n1 +O=C(Nc1cc(F)ccc1-n1cccn1)N1CCOCC1C1CC1 +c1nc2ccc(C3NCCc4ccc5cc[nH]c5c43)cc2[nH]1 +Cc1cccc(C)c1NC(=O)c1ncn(-c2ccccc2)n1 +CCC1CN(C(=O)NC(c2cccc(F)c2)c2nccn2C)CCO1 +O=C(CSc1nc(-c2ccccc2)n[nH]1)N1CCOCC1 +COC(=O)c1ccc2c(=O)[nH]c(C3CCC(C)CC3)nc2c1 +CCC(CC)NC(=O)C1CN(C(C)=O)c2ccccc2O1 +Cc1ccsc1C(=O)N1c2ccc(N)cc2CC1C +O=C(Cc1cccs1)NCc1cc(Cl)c2c(c1)OCCCO2 +CCC(C)NC(=O)C(C)NC(=O)Nc1cccc(F)c1 +Cc1ccc(SCc2cn3cccnc3n2)cc1 +Cc1noc2nc(-c3ccco3)cc(C(=O)N(C)CC(=O)N(C)C)c12 +COCCNC(=O)CNC(=O)Cc1cccc(F)c1F +CCCC(C)NC(=O)C1CC(=O)N(c2ccc(OC)cc2)C1 +COc1ccc(NC(=O)C2CCCCN2C(=O)C2CCCO2)cc1C +Cc1cccc(NC(=O)CCC(=O)c2ccc(F)cc2F)c1 +Cc1ccc2oc(C(=O)N3CCN(S(C)(=O)=O)CC3)cc2c1 +Cc1ccc(-n2nc3c(c2-n2cccc2)CN(C(=O)C(C)C)C3)cc1 +CC(C)C(NC(=O)c1cnc2snnc2c1)C(=O)NC1CCCC1 +O=C(NCc1ccccc1F)c1ccc(-n2cnnn2)cc1 +CCOc1ccc(C(=O)N(C)CC(=O)Nc2cccc(C)c2C)cc1 +CC(=O)c1cncc(-c2ccc(C(F)(F)F)cc2)c1 +CC(C)CC(=O)N1CCN(c2cc(N(C)C)cnn2)CC1 +O=C(NC1CCCCNC1=O)c1cc(C2CC2)nc2ccccc12 +COc1ccc(C(=O)Nc2ccccc2C(=O)NC(C)(C)C)cc1 +CCCC(=O)N1CCN(c2cc(N3CCCC3)nc(C)n2)CC1 +CN(C)c1cc(CNC(=O)Cc2cccnc2)nc(-c2ccncc2)n1 +CC(Sc1nccc(C(F)(F)F)n1)C(=O)N(C)C +CC(NCC(=O)NCc1ccccn1)c1ccncc1 +O=C(NC1CCC(c2ccccc2)CC1)c1ccc(-n2cncn2)nc1 +O=C(c1cnc(C2CCCO2)s1)N(CC1CCCCC1)C1CC1 +CCOCC12COCC1CN(Cc1scnc1C)C2 +COc1ccc(OCCNS(=O)(=O)c2ccc(F)c(F)c2)cc1 +NC(=O)c1ccc(NC2C(=O)Nc3cc(Br)ccc32)cc1 +CCOc1ccc(OCc2ccc(C(=O)Nc3cccnc3)o2)cc1 +Cc1ccsc1CN(C(C)C)S(=O)(=O)c1cnn(C)c1 +CC(C)C(NC(=O)Nc1ccccc1)C(=O)NCCc1ccccc1 +CC(=O)c1ccccc1NC(=O)CCc1c(C)nc(C)[nH]c1=O +O=C(CCn1cccc1)N1CCN(c2ncccn2)CC1 +Cc1ccc(SCCC(=O)Nc2nc(C)cs2)cc1 +Nc1c(Cl)ccc2c(C(=O)N3CCCC3)nccc12 +CCOC(=O)c1nn(Cc2ccncc2)c2ncccc12 +COCCNc1nnc(SC(C)c2cc(F)ccc2F)s1 +OCc1ccc(CNC2(Cc3cc(-c4ccccn4)on3)COC2)o1 +CCC(C)(C)C(=O)Nc1nc(CC(=O)OC)cs1 +COc1ccc2c(c1F)C(C(C)NC(C)=O)NCC2 +COc1ccc(OC)c(CC(=O)NCc2nnc3ccccn23)c1 +Cc1ccc(C(=O)NCc2ccncc2)c(Cl)c1 +CCc1ccc(Cn2c(=O)oc3cc(N)ccc32)cc1 +COc1cccc(NC(=O)C(C)Sc2nc3ncccc3o2)c1 +Cn1cc(Cl)c(C2CCCCCN2C(=O)c2ccco2)n1 +Fc1cccc(F)c1CCNCc1cccs1 +CC(C)(C)OC(=O)N1CCC(C(O)c2nccs2)CC1 +Cc1ccc(CN(C(=O)c2ccncc2F)c2ccc(F)cc2)o1 +Nc1ccc(Cl)c2c(C(=O)NCc3cccnc3)nccc12 +Cc1csc(NC(=O)Cn2c(=O)cnc3ccccc32)n1 +CC(=O)c1ccc(NC(=O)NCc2cccs2)cc1C +O=C(NCc1ccccn1)C1CC(=O)N(Cc2ccc(Cl)cc2)C1 +CCc1ccc2nc(N3CCN(C(=O)c4ccno4)CC3)sc2c1 +NS(=O)(=O)N1CCN(CCc2ccccn2)CC1 +CC(C)c1nc(-c2ccc(F)c(F)c2)n(CCO)n1 +Cc1onc(-c2ccccc2)c1C(=O)NC1CCC(C)CC1 +CSc1ccc(C(=O)Nc2cccc(C(=O)NC3CC3)c2)cc1 +CC(C)NC(=O)c1ccc(NC(=O)c2ccccc2O)cc1 +CCOc1ccc(Br)cc1NC(=O)CCOC +N#CC(NC(=O)Cc1c[nH]c2ccccc12)c1ccncc1 +CC(=O)N(C)c1ccc(NC(=O)c2ccccc2F)cc1 +Cc1ccc2ncc(C(=O)NC3CCOC4(CCCC4)C3)n2c1 +COC(=O)Cn1cc(NC(=O)c2ccc(F)cc2Cl)cn1 +Cc1nnc(-c2cccc(C#N)c2)n1Cc1ccccn1 +Cc1cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)c(C)n1C(C)C +Cc1ccc(C)c(S(=O)(=O)N(C)C2CCCCC2O)c1 +Cc1cc(-n2nc(C)cc2C)n2nc(C(F)(F)F)nc2n1 +Cc1cc(NC(=O)C2(C#N)CCCC2)nc2nc(C(F)(F)F)nn12 +COc1ccccc1C(=O)Nc1nn(C)c2nc(C)ccc12 +O=C(Nc1ccncc1)c1cc(F)c(Cl)cc1Cl +Cc1oc2ncn(CC(C)C)c(=O)c2c1C(=O)Nc1cccc(F)c1 +C=C(C)CN(CC)C(=O)CNc1cc(C#N)ccc1Cl +COC(=O)c1ccc2c(c1)[nH]c(=O)n2C(=O)c1ccccc1 +N#Cc1ccccc1N1CCCN(Cc2cc[nH]n2)CC1 +CC1Sc2ccc(C(=O)NC(C)c3ccco3)cc2NC1=O +NC(Cc1cc(F)cc(F)c1)C(=O)NCCCO +COc1cc2nc3c(c(Cl)c2cc1OC)CCC3 +CC(OC(=O)CCSc1ccc(F)cc1)c1ccccn1 +Cc1cc(C(N)=O)ccc1NCCc1ccccc1 +CC(=O)Nc1cc(NC(=O)Cc2ccc(F)cc2)ccc1F +CCOc1cc(CNC(=O)NCCC(=O)N(C)C)ccn1 +Cc1ccnc2nc(NC(=O)c3ccc(C(C)(C)C)cc3)nn12 +CCOC(=O)C1C(=O)n2ncnc2NC1C(C)C +CCCn1cc(C(=O)N2CCCC2C(=O)NCC2CCCCC2)cn1 +CC(=O)Nc1nc(C(=O)Nc2ccc(N3CCCCC3)nc2)cs1 +Cc1cc(C)c(C(=O)CCC(=O)N2CCN(C)CC2)c(C)c1 +O=C(Nc1ccnn1C1CCCC1)c1cc(Cl)ccn1 +Cc1nn(C)cc1CN1CCN(c2ccnc(-c3ccccc3)n2)CC1 +COc1ccc(C(O)CNC(=O)CCn2cnc3ccccc32)cc1 +Cc1ccc(C(=O)N2CCc3nc(-c4ccc(F)cc4)ncc3C2)cc1 +COCCOC(=O)c1cc(C(=O)Nc2ccc(F)cc2)c(=O)[nH]c1C +Cc1nc2ccccc2nc1SCCS(=O)c1ccccc1 +CC(OC(=O)C1(Cc2nc3ccccc3s2)CCCC1)C(N)=O +CC(=O)c1cc(-c2ccc3nc(C)oc3c2)n(C2CC2)c1C +COc1ccc(CNc2ccc(C#N)cc2)cc1C +Cc1cccc(C)c1NC(=O)CN(C)C(=O)c1cccnc1 +Cc1c(-c2ccccc2)nc2ccccc2c1C(=O)OCC(=O)N(C)C +CCc1cc(C(=O)N2CCCC2c2ccc(OC)cc2OC)no1 +COc1ccc(CCNC(=O)C2CCN(C(=O)C(C)(C)C)CC2)cc1 +O=C(C1CCC1)N(Cc1ccco1)CC1CCCO1 +COCC(=O)Oc1ccc2cc(-c3ccccn3)c(=O)oc2c1 +CC(O)(CNC(=O)c1cccs1)c1cccs1 +CS(=O)(=O)c1cc(C(=O)N2CC(O)C2)ccc1Cl +CCN1C(=O)C(C)(C(=O)N2CCOCC2)Oc2ccccc21 +COc1ccncc1NC(=O)c1ccc2c(c1)nc(C)n2C +CCn1cnnc1CNC(=O)C(C)Oc1ccc(C)cc1 +CN(C)S(=O)(=O)NCC(O)c1ccc2c(c1)OCO2 +Cc1ccc2[nH]cc(NC(=O)NCCO)c(=O)c2c1 +Cn1c(=O)c(C(=O)NCc2c(F)cccc2F)cc2cccnc21 +COc1ccc(OCC(=O)Nc2nnc(C3CCCCC3)o2)cc1 +CCc1ccc(S(=O)(=O)NC(C#N)c2cccnc2)cc1 +Cn1c(N)nnc1SCc1c(F)cccc1Br +Cc1nn(CC(=O)NC2CCCCCC2)c(=O)c(C#N)c1C +CCc1ccc(C(=O)Nc2ccc(OC)c(-n3nnnc3C)c2)s1 +COc1cc(C(=O)NCC2CCCO2)cc2occc12 +Cc1ccc(CN(C(=O)Cc2cccc(OCC#N)c2)C(C)C)o1 +O=C(NCCCn1cccn1)NC1(c2ccc(Cl)cc2)CC1 +COc1ccccc1C(=O)NC1CCN(c2ccc(C)cc2)C1=O +CC(C)(C)c1nnc(CNc2cccc(-c3nnnn3C3CC3)c2)o1 +CCn1nc(C)c(S(=O)(=O)N2CCN(c3ccccc3)CC2)c1C +COCCN(CCOC)c1ncnc2c1cnn2C +Cc1cc(C)nc(C2CCN(c3cnccn3)C2)n1 +COc1ccc(C(C)=O)cc1CC(=O)NCCC(C)C +Cc1nc(CNC(=O)CCc2cn(C)c3ccccc23)c(C)s1 +Cc1cc(NC(=O)Cc2ccccc2O)ccc1OCCO +CCOC(C)C(=O)OCC(=O)NC1CCCc2ccccc21 +NC(=O)CN(C(=O)c1cc2c(ccc3ccccc32)[nH]1)C1CCCC1 +COCCCN(C)C(=O)c1ccc(-c2nc(C)cs2)cc1 +Cc1nc(C)c(CCC(=O)N2CCCC2c2ccsc2)c(=O)[nH]1 +Cc1cccc(OCCOC(=O)c2sccc2S(N)(=O)=O)c1 +COCc1nn(C)c(N)c1-c1nc2ccccc2s1 +CCOc1cccc(CNC(=O)c2cccs2)c1 +Cc1c(CCC(=O)Nc2ccc(OCCO)cc2)cnn1C +CN(C)C(=O)c1cc(=O)[nH]c2c(Br)cccc12 +Clc1ccc(OCc2nnc(-c3cccnc3)o2)c(Cl)c1 +CCc1[nH]nc(C(=O)NC(C)Cc2ccsc2)c1N +Cc1ccc(-c2cc(C(=O)NC(C)C(=O)N3CCCCC3)on2)cc1 +FC(F)(F)c1nc(N2CCCCC2)c2cnn(-c3ccccc3)c2n1 +COc1ccc(-n2ccc(CNc3ncccc3C#N)n2)cc1 +CCCN1C(=O)CCc2cc(NC(=O)c3ccccc3OC)ccc21 +Cc1cnc(C(=O)OC(C)C(=O)NCc2ccco2)cn1 +O=C(Cc1ccc[nH]1)Nc1ccccc1C(=O)N1CCCCC1 +CCCCCCNC(=O)c1cnc(C2CCCCC2)nc1N +Cc1ccc(N)c(Oc2ccc(Br)cc2)n1 +Cn1cccc1C1COCCN1C(=O)CC1C(=O)Nc2ccccc21 +O=c1ccc(C2NCCc3c(F)ccc(Cl)c32)n[nH]1 +COc1ccc(Nc2nc3[nH]nc(N)c3c3c2CN(C)CC3)cc1 +CS(=O)(=O)NCCNc1ccccc1S(N)(=O)=O +O=C(CNc1ccc(F)cc1)NCc1cccc(NC(=O)C2CC2)c1 +CCOC(=O)c1ccc(CNC(=O)c2c(C)nn(C)c2C)o1 +COC(=O)CCCCC1=CCC2C(=O)CC(=O)C2C1 +Cc1ccccc1NC(=O)C(C)S(=O)(=O)c1ccc(F)c(F)c1 +Cc1nc2ccccc2n(CCC(=O)NCC2CCCO2)c1=O +CC(=O)NC1CCCN(C(=O)Nc2cc(-n3cccc3)ccc2F)C1 +COC(=O)c1ccccc1NC(=O)COC(=O)c1ccc(F)cc1N +Cc1ccc(NC(=O)c2ccc3n[nH]c(=O)n3c2)cc1 +CC(C)(CNC(=O)Cc1ccc[nH]1)c1cccc(F)c1 +Cc1nnc(CNc2ccccc2NC(=O)Cc2cccs2)n1C +C=CCN(C(=O)c1cccc2[nH]ncc12)C1CCCC1 +Cc1cc2cccc(C(=O)NCCCN3CCOCC3)c2o1 +COc1ccccc1N(CCC(N)=O)C(=O)c1ccc2ccccc2c1 +Cn1ccc(C(=O)Nc2ccc(Cl)cc2-n2cccc2)cc1=O +CC1CN(c2ccccc2NC(=O)NC2CCC(O)CC2)CC(C)O1 +Cn1cc(C(=O)NCc2ccnc3ccccc23)c(C(C)(C)C)n1 +CCSc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1cccc(C)c1 +C#CCOc1cc(CNC(=O)N2CCC(CO)CC2)ccc1OC +NC(=O)N1CCC2(CC1)CC(C(=O)NC1CC1)Oc1ccccc12 +COCCCC(=O)Nc1ccccc1C(=O)C(C)C +CC(C)CN(C(=O)CCc1nc(-c2ccccn2)no1)C1CC1 +Cn1c(NCc2ccc(-n3cncn3)cc2)c(C#N)c(=O)n(C)c1=O +Cn1cc(CCNS(=O)(=O)c2cccc(C#N)c2)c2cccnc21 +CN(Cc1ccc(F)cc1Cl)C(=O)c1cc(C(N)=O)cs1 +CC(NC(=O)c1ccccc1)C(=O)NC1CCCC(C)C1C +COc1cccc(C(=O)N(Cc2cccs2)C2CC2)c1 +CCc1nc(COc2cccc(-c3nnco3)c2)cs1 +CCn1nc(C(=O)N2CC3CCC2CN(S(C)(=O)=O)C3)cc1C +O=C1CC(C2NCCc3c(F)ccc(Cl)c32)C1 +CNC(=O)COC1CN(C(=O)c2cccc(C#N)c2)C1 +N#Cc1ncn(CC(=O)N2CCCc3ccccc32)n1 +COc1cc(OC)c(OC)cc1CNC(=O)c1cc2ccccc2[nH]1 +CCn1c(C(=O)NCC2CCCO2)cc2sccc21 +FC(F)(F)c1ccc2c(c1)CCNC2c1cc[nH]c1 +CC(=O)N1CCN(C(C)C(=O)N2CCCCC2)CC1 +Cc1ccc(NC(=O)CN2CCOC(c3ccsc3)C2)c(C)c1 +COC(=O)c1ccc(NC(=O)Cn2ncc3ccccc32)s1 +CCC1C(=O)NCCN1Cc1cnc(C2CCC2)s1 +NC(=O)C(Cc1ccccc1)NC(=O)c1cccc(-n2cncn2)c1 +CC(=O)OCC1CCC(n2cnc3c(=O)[nH]cnc32)O1 +O=C(NCCc1cccs1)NCc1nnc2ccccn12 +Cc1ccc(-c2nc(NC(=O)c3ccnc(F)c3)sc2C)s1 +CCS(=O)(=O)NC1CCN(c2ccccc2)C1=O +COc1cc2c(cc1OC)CN(C(=O)C1CCC1)CC2 +CC(C)c1ccc(C(=O)Nc2cc(F)ccc2F)c(N)n1 +Cn1ncc(C(=O)Nc2cccc(Cn3ccnc3)c2)c1-n1cccc1 +COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)Nc1ccccc1 +Cn1cc(C(=O)Nc2cccc(NC(=O)C3CC3)c2)c2ccccc21 +CC(NCCc1ccccn1)c1c(F)cccc1F +C=CCNC(=O)Cn1c(CNC(=O)CC)nc2ccccc21 +O=C(Nc1ccncc1)c1cccc(Br)c1 +CC(Oc1ccccc1F)C(=O)NCCOc1ccc(F)cc1 +COC(=O)c1cc(S(=O)(=O)N(C)Cc2ccccc2)cn1C +Cn1nc(C(C)(C)C)cc1C(=O)N1CCN(c2ccccc2O)CC1 +FC(F)(F)C1=CCN(Cc2ccn(-c3ccccc3)n2)CC1 +C=CCNC(=O)NC1CC(C)(C)Cc2nc(N3CCOCC3)ncc21 +Cc1ccc(-c2ncc(C(=O)NCCn3cccn3)s2)c(C)c1 +CC(C)c1nc(Cn2ccnc2-c2ccc(-c3cc[nH]n3)s2)no1 +O=C(COC(=O)c1cc(F)cc(F)c1)NCc1ccccc1 +C=CCn1c(=O)n(CC=C)c(=O)n(CC(=O)N2CCCC(C)C2)c1=O +Brc1ccccc1OCC#CCN1CCOCC1 +C=CCOCC12CCCOC1CCN(Cc1cccs1)C2 +Cc1cc(C)n(-c2ccc(C(C)Nc3ccc(C(N)=O)nn3)cc2)n1 +CCCOc1cccc(C(=O)N(C)CC(=O)N(C)C)c1 +CC(NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)NCc1ncn(C)n1 +Cc1cc(CC#N)nn1-c1ccc(C(F)(F)F)cc1 +CN1C(=O)C2(CCN(C(=O)Cc3cccc(F)c3)C2)c2ccccc21 +CCN1CCN(C(=O)c2nccc3c(N)c(Cl)ccc23)CC1 +COc1cccc(C(=O)NC(C)(C)c2ncc(C)s2)c1F +CCN(CCC#N)C(=O)COc1ccccc1C(F)(F)F +Cc1ccc(NC(=O)C(C)NC(N)=O)c2[nH]ncc12 +Cn1cc(C(=O)Cn2cc(-c3ccccc3)sc2=O)cn1 +COc1ccc(F)cc1NC(=O)NCCC(=O)N1CCCCCC1 +CC(C(=O)Nc1cc(F)ccc1F)c1cccs1 +CCc1ccccc1NC(=O)c1ccc(OC)nn1 +CCCS(=O)(=O)N1CCC(C(=O)Nc2ccc(C)cc2C)CC1 +COc1ccccc1NCC(=O)Nc1ccccc1C(=O)NC(C)C +COCc1cccc(CNC(=O)c2ccc(N(C)C)cc2)c1 +CCn1ccc(CNc2cc(OC)ccc2OC)n1 +COc1cc2c(cc1Cl)C(c1ccco1)NCC2 +COc1ccc(CC(=O)Nc2nnc(-c3cc(C)n(C)n3)o2)cc1 +Cc1csc(N2CCCN(C(=O)Cc3csc(C)n3)CC2)n1 +NC(=O)c1cnc(NCCC(=O)N2CCCC2)c(Cl)c1 +CSc1ccc(CNC(=O)c2cn3cc(C)ccc3n2)cc1 +CC(=O)c1ccc(-n2ccc3c(cnc4nc(C)nn43)c2=O)cc1 +CCc1nc2ccccc2c(=O)n1CC(=O)Nc1c(C)cc(C)cc1C +O=C1Nc2ccc(Cl)cc2C1(O)c1c[nH]c2ccccc12 +CN(CC1CCCC1)C(=O)CCNC(=O)c1cccs1 +COc1ccc(NS(=O)(=O)c2ccccc2Cl)c(OC)c1 +CCCCN1C=NS(=O)(=O)c2ccc(C)cc21 +COC(=O)CCN(C)C(=O)C(C)Oc1ccccc1 +O=C1COc2ccc(C(=O)COC(=O)c3ccc(O)cc3O)cc2N1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)N(C)C)ccc21 +CCCC(=O)Nc1c(C(=O)OCC)[nH]c2ccc(OC)cc12 +Cn1c(=O)n(C2CCN(C(=O)c3cccs3)CC2)c2ncncc21 +CCC(CO)NC(=O)c1ccc(CNC(N)=O)cc1 +COC(=O)C(N)Cc1cn(Cc2ccccc2)cn1 +CNC(=O)Cc1ccc(NCC(=O)Nc2ccc(C(N)=O)cc2)cc1 +CC(C)c1nc(CN2CCCN(c3ncnc4[nH]ccc34)CC2)no1 +CCCn1cc(NC(=O)c2cc(-c3ccccc3)[nH]n2)ccc1=O +Cc1nnc2c(N3CCCC(C)C3)nc3ccccc3n12 +CN(Cc1ccc(C#N)cc1)C(=O)Nc1cnn(-c2ccccc2F)c1 +CCCS(=O)(=O)N1CCC(S(=O)(=O)c2nncn2C)CC1 +Cc1cc(C)c(C(=O)N2CCCC(C(=O)NCc3ccc(C)o3)C2)[nH]1 +O=c1cc(-c2nc(-c3ccc(Oc4ccccc4)cc3)no2)[nH]c(=O)[nH]1 +COc1cccc(CCC(=O)Nc2nc3c(s2)CN(C)CC3)c1 +CCCC(C)(C)NC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +Cc1ccc(-c2c(C#N)c(N)nc(SCCO)c2C#N)o1 +O=C(Nc1cccc(-c2nc3ccccc3[nH]2)c1)c1cnccn1 +CNC(=O)CNC(=O)c1nn(C)c2ccc(F)cc2c1=O +COc1ccc(-n2cc(CNC(=O)CC(C)C(C)C)nn2)cc1 +CC(C)CNC(=O)C(C)Sc1ccccc1F +Cc1ccccc1CC(=O)NC1CNc2ccccc2C1 +Cc1ccc2c(c1)nc(CC#N)n2CC(=O)N1CCCC1 +COc1ccc(NC(=O)CC2OC(=O)c3ccccc32)cc1F +O=C(NCc1ccc2c(c1)CCC2)Nc1ccncc1 +COc1ccc(NC(=O)CC2NC(=O)c3ccccc3NC2=O)cn1 +C=CCNC(=O)Cc1csc(COc2ccccc2)n1 +COC(=O)CCSc1nnc(-c2ccc(Cl)cc2Cl)n1N +COc1ccc(NC(=O)Cc2ccc(C)nc2)cc1C +CC(NC(=O)c1cccc(S(=O)(=O)N2CCCC2)c1)C1CC1 +CC(NS(C)(=O)=O)C(=O)NC1CCc2ccccc21 +CCc1nnc2n1CCN(C(=O)c1cn(C)nc1C1CCCCC1)C2 +C#CCN(Cc1ccco1)S(=O)(=O)c1cccc(C)c1 +CCCn1cc(-c2ccnc(NC3COC4(CCCC4)C3)n2)c(C)n1 +CCn1nc(C)c(CCN2Cc3ncccc3C2=O)c1C +NC(=O)C(OC(=O)Cn1c(=O)oc2ccccc21)c1ccccc1 +Cc1nc2n(c1C)CCN(CC(O)COCc1ccco1)C2 +COCCNC(=O)C(C)n1nc(-c2ccccc2)ccc1=O +CCN(CCC#N)C(=O)CSc1nc2cc(Cl)ccc2s1 +CCNS(=O)(=O)c1c(NC)nc2ccccn12 +CCc1nc2ccccc2c(C(=O)NCc2c(C)noc2C)c1C +Nc1ccc(C(=O)Cc2nc(-c3ccccc3)cs2)cc1 +O=C(CCOc1ccccc1)N1CCC(c2cc[nH]n2)C1 +C#CCNc1cc(S(=O)(=O)N2CCCCC2)ccc1C +CCCn1c(C)nnc1SCc1cc(C#N)ccc1F +CC(C)NC(=O)c1ccc(Cl)cc1NC(=O)C(C)NC(N)=O +COCCn1nc(-c2ccccn2)cc(CC#N)c1=O +CC(NCCc1nc(-c2ccccn2)cs1)c1ccco1 +COc1nccc2cccc(NCc3ccccc3)c12 +CC(=O)Nc1ccc(C(=O)c2cc3ccccc3o2)cc1 +CCOC(=O)c1cnc(CC)nc1-c1ccccc1Br +CN(C)c1ccc(NC(=O)c2cncc(Br)c2)nc1 +O=C1CCC(C2NCCc3c2ccc(F)c3O)N1 +Cn1cccc1C(=O)NCc1ccc2c(c1)OCCO2 +Cc1nn(C)c(C)c1CNc1ncnc2c(Br)cccc12 +N#CC(c1ccccc1)N1CCN(C(=O)c2ccc3cc[nH]c3c2)CC1 +O=C(NC1CC1)c1cc2n(n1)CCN(Cc1cccc(Cl)c1)C2=O +NC(=O)C1CN(C(=O)NCCc2c(F)cccc2F)CCO1 +O=C(CCNC(=O)C1Cc2ccccc2S1)NCc1cccnc1 +CC(C)CSc1nc2c(c(=O)[nH]c(=O)n2C)n1C(C)C +CCC(C)(O)CNC(=O)C1CC(=O)N(Cc2ccco2)C1 +O=C(NCC1CC1)Nc1cccc(Cn2nc3ccccn3c2=O)c1 +Cc1cn2nc(N3CCCC(N4CCNC4=O)C3)sc2n1 +O=C(CCc1n[nH]c(=O)[nH]c1=O)NCc1ccccc1 +COc1ccccc1N1CCN(C(=O)C(C)c2cccs2)CC1 +Cc1ccccc1C(=O)NCCC(=O)N1CCc2sccc2C1 +CCOC(=O)CN(CC)C(=O)Cc1c(C)n[nH]c1C +CNc1ccc(S(=O)(=O)N(C)C(C)CC(C)C)cn1 +CCN(C(=O)Cc1c(C)nn(CC(F)(F)F)c1C)c1ccncc1 +COc1c(C)cnc(COc2cc(F)ccc2N)c1C +CCCn1nc(C)c(C(=O)NCC(C)(C)c2ccncc2)c1C +CCn1c(C2CCN(C(=O)CCn3nnnc3C)CC2)nn(C)c1=O +O=C(Nc1ccc2oc(=O)[nH]c2c1)c1ccccc1F +CCc1nc2n(n1)CCCC2NC(=O)Nc1nc2ccccc2s1 +CCC(=O)Nc1cccc(NC(=O)c2ccccc2)c1C +COc1cc(C(=O)Nc2ccncc2)cc(OC)c1OCC(N)=O +CCOC(=O)C1CCCN(C(=O)C(C)Sc2nc(C)c(C)o2)C1 +Cc1ccc(C)c(C(=O)CCC(=O)Nc2ccncc2)c1 +C#CCN1CCC(C(=O)Nc2cc(Cl)c(N)c(Cl)c2)CC1 +COc1ccc(Cl)cc1NC(=O)CCn1ccnn1 +O=C(c1cccs1)N1CCN(Cc2cnc3ccccn23)CC1 +CCOC(=O)N1CCN(C(=O)Nc2ccc(C)c(NC(C)=O)c2)CC1 +CC(C)S(=O)(=O)Nc1cnn(CCc2ccccc2)c1 +O=C(CCC(=O)c1ccccc1)Nc1cnc2ccccc2c1 +Cn1c(-c2c(COc3ccccc3)n[nH]c2N)nc2ccccc21 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc2c(c1)CCC2 +CCCCNC(=O)C1CCN(c2nc(OC)nc(OC)n2)CC1 +CCc1nc(CNc2ccc(S(C)(=O)=O)cc2C)cs1 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+Cc1ccc(Cn2nc(C)c3c(C)onc3c2=O)cc1 +COc1cccc(C2CC(O)=Nc3c2ncn3-c2ccccc2)c1 +COc1c(C)cnc(CN(C)C(=O)c2cccc(NC(N)=O)c2)c1C +COC(=O)C1CCCN1C(=O)c1ccc2c(c1)CCN2C(C)=O +Cc1ccccc1S(=O)(=O)c1c(C)cc(C)n(C)c1=O +Cc1noc(-c2cccc(F)c2)c1C(=O)NCCOC(C)C +COc1ccc(CCNC(=O)c2scc3c2OCO3)cc1 +Cc1ccsc1-c1nn2c(-c3c(Cl)cnn3C)nnc2s1 +O=C(NC1CCN(C(=O)c2ccc3[nH]nnc3c2)CC1)c1ccccc1 +COC(=O)C1CCN(C(=O)CCOc2cccc(F)c2)CC1 +Cc1ocnc1CNC(=O)Nc1ccc(NC(=O)C2CC2)cc1 +Cc1cc(Sc2ccccc2)ccc1NC(=O)N(C)CCC#N +Cc1nnnn1-c1cccc(NC(=O)N2CCOCC2CC(C)C)c1 +Cc1cc(C)nc(N2CCCC2c2nc(-c3ccncc3)cc(=O)[nH]2)n1 +CCc1cc(NCCn2cc(Cl)cn2)n2nccc2n1 +CCOC(=O)C(NC)c1nnc2sc3ccccc3n12 +COc1ccc(OC(=O)c2c(C)c(C)nn(C)c2=O)cc1 +COC(=O)c1cccc(Cn2c(C(C)C)ccc(C#N)c2=O)c1 +COc1ccc(C(=O)NCCc2ccccn2)c(O)c1 +CNC(=O)C1CCN(C(=O)Nc2ccccc2SC(F)F)CC1 +CCS(=O)(=O)N1CC2CN(C(=O)c3cscn3)CC2C1 +COC(=O)CNC(=O)c1cnc2sc(C)cn2c1=O +CCCN(CCOC)C(=O)c1[nH]nc(CC)c1C +Cc1nc(COc2ccc(F)c(F)c2)nc(C)c1N +CN(CC(=O)NC1CC1)c1ncc(C(F)(F)F)cc1Cl +CC(NS(=O)(=O)CC(C)(C)CO)c1ccccc1 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+CNC(=O)c1ccc(CN(C(=O)c2ccc(Cl)cc2)C2CC2)cc1 +COc1ccc(OC)c(CN(C)C(=O)c2cc(F)ccc2OC)c1 +Cc1noc(CCC(=O)Nc2c[nH]cc(Br)c2=O)n1 +Cc1ccc(N2CCCCn3c2nc2c3c(=O)n(C)c(=O)n2C)cc1 +O=C(CC(c1cccc(F)c1)n1cccc1)Nc1cccnc1 +C#CCn1c(C2CC(=O)N(C)C2)nc2ccccc21 +Cc1cc(C)cc(NC(=O)Cn2nnc3ccccc3c2=O)c1 +O=C(CSc1ccc2c(c1)OCCO2)Nc1ccc2c(c1)CCC2 +O=C(Cn1cccn1)Nc1cccc(CNC(=O)NC2CC2)c1 +CCOC(=O)c1cccc(NC(=O)C2CCCO2)c1C +CN(C(=O)CCNC(=O)c1cc(F)ccc1Br)C1CC1 +O=C(Nn1c(C2CCCCC2)nc2ccccc2c1=O)c1ccco1 +Cc1nccc(CNC(=O)C(C)(C)Oc2cccc(Cl)c2)n1 +CCOC(=O)C(N)CCOC1CC(C)CC(C)(C)C1 +Cn1nc(C(=O)NCc2ccccc2Cn2ccnc2)ccc1=O +CC(C)(NC(=O)CCCc1cc(F)ccc1F)c1nccs1 +COC(=O)CCn1nc(C)c(CN2CC3OCCN(C)C3C2)c1C +COc1coc(C(=O)Nc2ccc(Cl)cc2)cc1=O +COc1cc(C)ccc1CNC(=O)c1cccc(OC)c1F +CN(Cc1cccc(C#N)c1)C(=O)Nc1c(F)cccc1F +Cn1cc(NC(=O)N2CCCC(C(=O)c3cccs3)C2)cn1 +OC(CNc1ncnc2sccc12)c1ccccc1F +O=C(c1c(F)cccc1F)N1CCC(O)(c2cccnc2)CC1 +CCc1onc(C)c1NC(=O)CCOc1c(C)cccc1C +CCOC(=O)C(Cc1nnc2oc3ccccc3n12)NC +O=C(CN1CCCCC1=O)Nc1ccccc1-c1ccccc1 +Cc1cc(SCCC(=O)Nc2cc(C)on2)nc(C)n1 +CCOC(=O)CSc1nnc(-c2ccc(N)cc2)n1C +O=C(Nc1ccccc1F)c1cnc2ccccn2c1=O +Cc1ccc2nnc(C(=O)NCc3ccco3)nc2c1 +O=C(OCC(F)(F)F)c1ccc(Cn2ccccc2=O)o1 +Cc1nc(CC(=O)NCCCSc2ccc(F)cc2)cs1 +O=S(=O)(CCC1CCCO1)NCCc1ccccc1F +CCn1ccnc1N1CCN(C(=O)c2c(F)cccc2F)CC1 +O=C(NCCCCn1ccccc1=O)Nc1cccnc1 +CC(NC(=O)Cn1cccn1)c1nnc2n1CCCCC2 +CCCc1noc(-c2cc(-c3ccc(O)cc3)n[nH]2)n1 +COC(=O)C(NC(=O)c1ccc(Br)cc1)C(C)C +CC1(C(=O)N2CCOCC2)CCCN(c2ncccn2)C1 +Cc1ccc(-c2nc(-c3cccnc3)cc3n[nH]c(=O)n23)cc1 +CCc1cc(NC(=O)c2cccc(OCC(F)F)n2)[nH]n1 +Nc1cccc2c1CN(c1ccccc1Br)C2 +Cc1cc(C)n2nc(C(=O)Nc3ccccc3Br)nc2n1 +CC(C)NC(=O)CNC(=O)CCc1ccc(Br)cc1F +NS(=O)(=O)C1C=CN=C(Br)C1OC1CC1 +O=C(Nc1ccccc1Cl)C1OCCc2ccccc21 +CC(=O)N1CCc2ccc(NC(=O)c3ccc(F)cc3F)cc21 +CC(CCO)NS(=O)(=O)c1ccc(Br)cn1 +CCOC(=O)c1c(C)csc1NC(=O)c1ccc(NC(C)=O)cc1 +O=c1c2cnc(C(F)(F)F)nc2nc2sccn12 +Cc1nn2cccnc2c1C(=O)Nc1ccc2c(c1)COC2 +CCOC(=O)Cn1c(C)nc2sc(CC)cc2c1=O +Cc1nc(-c2cc(C(=O)N(C)CCc3ccccn3)n(C)c2)cs1 +CC(C)NC(=O)CNS(=O)(=O)c1cccs1 +COc1ccc(C(=O)Nc2cccc(NC(C)=O)c2)cc1OC +COc1cc(C(=O)NC2CCC(C(=O)N3CCOCC3)C2)ccn1 +Cc1c(Cl)cccc1S(=O)(=O)NCCC(O)c1ccccc1 +CC1(O)CCN(C(=O)c2ccc(-c3noc(C4CC4)n3)cc2)CC1O +CC1CCc2c(sc(NC(=O)c3ccnn3C)c2C#N)C1 +COc1cc(NC(=O)NC(C)C(C)C)ccc1NC(C)=O +Cn1ccsc1=NC(=O)CCCNC(=O)c1ccc(Cl)cc1 +N#Cc1ccc(-c2noc(CCCOc3ccccc3F)n2)nc1 +CCc1cccc(NC(C)C(=O)N(C)CC(=O)NC2CC2)c1 +COc1ccc(C(=O)N=c2[nH]c3ccccc3n2-c2ccccc2)nn1 +Cc1cccc(NCC(=O)NCC2CN(CC(C)C)CCO2)c1C +CN(Cc1ccc(F)cc1)C(=O)CNC(=O)COc1ccccc1 +COc1ccccc1Cn1cc2c(c(C#N)c1=O)CCCC2 +COc1cc(NC(=O)CCc2ccccc2)ccc1NS(C)(=O)=O +Cc1c(C(=O)NCCO)cnn1-c1ccc(F)cc1 +Cn1cncc1C1NCCc2ccc3c(c21)CCO3 +Cc1ccc(SCC(=O)c2ccc(NS(C)(=O)=O)cc2)nc1 +CC(C)c1ccc(C(O)CNC(=O)CCc2ccco2)cc1 +CCN(c1ccc(C(=O)NC2c3ccccc3CC2O)cc1)C(C)C +NC(=O)Cn1cc(NC(=O)NCc2ccncc2)cn1 +CC(C)(C)OC(=O)NCc1nnc(-c2ccc(Cl)cc2)o1 +CNS(=O)(=O)C1CCN(C(=O)c2scnc2C2CC2)C1 +COc1ccc(C(=O)NCC(C)C)cc1S(=O)(=O)NC(C)C +CCn1cc(S(=O)(=O)c2ccc(OC)cc2)c(=O)c2ccccc21 +CCN(Cc1ccccc1)Cc1c(O)c(=O)cc(C)n1CC +Cc1cccc(OCC(=O)N(C)CCC(F)(F)F)c1 +CCOc1ccc(CC(=O)NCC2CCN(C(=O)OC)CC2)cc1 +CCCN1C=NS(=O)(=O)c2cc(C(=O)N3CCOCC3)ccc21 +CC(O)CNC(=O)c1cccc(OCc2csc(C(C)C)n2)c1 +Cc1nn(C(F)F)c(C)c1CC(=O)N=c1[nH]ncn1-c1ccccc1 +CCC(C(=O)Nc1ccc(F)cc1)N1CCN(c2nccs2)CC1 +CCNS(=O)(=O)c1cc(C(=O)Nc2ccc(C)cc2)ccc1OC +O=C(NCCNc1cnccn1)c1cc(Cl)c2c(c1)OCCO2 +COc1cc(CN2CCCc3ccccc32)ccc1OCCO +CC(NC(=O)NCC(O)C(C)(C)C)C(=O)N1CCCCC1C +CCCCn1c(N)c(N(C)Cc2ccc(C#N)cc2F)c(=O)[nH]c1=O +Cc1ccc(CC(=O)OCC(=O)NCC(F)(F)F)cc1C +Cc1occc1C(=O)N(CCC#N)Cc1cccnc1 +CNC(=O)c1cccc(NS(=O)(=O)c2ccc(C)cc2)c1 +Cc1ccccc1-n1ccnc1SCC(=O)NC1CCCC1 +O=C(OCc1cccnc1)c1ccc(OC(F)F)cc1 +COc1ccc(C(=O)NCCn2ccc3c(OC)cccc32)cc1 +CCCNc1ccc(Cl)c(C(=O)N2CCC(O)C2)n1 +CCOc1cc2c(cc1OCC)CN(C(=O)c1ccccc1O)CC2 +O=C(NCCc1nc(-c2ccncc2)n[nH]1)c1cccnc1 +CN(CCc1cnn(C)c1)C(=O)CN1CCN(c2ncccn2)CC1 +Cc1c(C(N)=O)nnn1CC(=O)N1CCCCC1 +Cc1nnc(SCC(=O)N2CC(C)CC(C)C2)n1CC(N)=O +N#Cc1cc(-c2ccccc2Cl)cnc1N1CCOCC1 +COCc1nc(NCc2ccc(C)cc2)cc(OC)n1 +O=C(NCc1ccnc(OC2CCC2)c1)C1CC1c1cccc(F)c1 +Cc1cc(NC(=O)C(C)(C)Oc2ccc(F)cc2)n(C)n1 +Cc1ncsc1C(=O)OCc1cc(Cl)c2c(c1)OCO2 +COc1ccc(-n2ccc(CNC(=O)NC(C)C(C)CO)n2)cc1 +CCN(CC)C(=O)Cn1c(COC)nc2c(N)cccc21 +CCC(Nc1cccc(OC)c1)C(=O)Nc1cc(C)on1 +CCOC(=O)C1CCCCN1S(=O)(=O)c1cn[nH]c1 +CC(c1ccncc1)N(C)C(=O)c1cncc(Br)c1 +CCCS(=O)(=O)N1CCCC1C(=O)Nc1cc(C)nn1C +Cc1nn(C)c2sc(C(=O)NCC3(c4ccccc4)CCC3)cc12 +Nc1cc(N)nc(SCCc2cccs2)n1 +O=C(C(O)c1ccccc1)N(CCO)Cc1ccsc1 +CCOc1ccc(C(=O)Nc2c(C)cccc2C)cc1OC +O=C(Nc1ccc2c(c1)OCO2)N1CCCC1c1cccs1 +Cc1ccn(CC(C)CNS(=O)(=O)c2cnn(C(F)F)c2C)n1 +Cc1sc2nc(CSc3n[nH]c(N)n3)nc(N)c2c1C +CCCNC(=O)NC1CCN(C(=O)OC(C)(C)C)CC1 +Cc1nc(-c2nnc(SCC(=O)c3ccccc3)o2)cs1 +O=C(NC1C2CCOC2C12CCC2)c1cccc(OCC(F)F)n1 +CN(CC(=O)Nc1ccc(Cl)cc1)C(=O)c1ccc(=O)[nH]n1 +CCc1ccccc1NC(=O)Cn1cnc2cc3c(cc21)OCCO3 +CC(C)(CNC(=O)c1ccc(F)cc1)N1CCOCC1 +CCc1ccc2c(c1)S(=O)(=O)N=C(NC(C)(C)CO)N2 +Cc1cnn(CC2CCCN2C(=O)Cc2cn(C)c3ccccc23)c1 +CC(C)c1cc(NS(=O)(=O)Cc2cccc(C(F)(F)F)c2)[nH]n1 +CCn1cc(Br)cc1C(=O)Nc1nnc(C2CC2)o1 +O=C(Nc1nncs1)c1coc(-c2ccccc2)n1 +CN(C)S(=O)(=O)NCC1(N2CCOCC2)CCCCC1 +CC(NC(=O)NCc1ccnc(OCC(F)(F)F)c1)C1CCCO1 +COc1cc(Cl)c(C)cc1NC(=O)COc1ccccc1C(N)=O +CCOc1c(Cl)cc(C(=O)N2CCC(C)CC2C)cc1OC +Cc1ccc(NC(=O)c2c(C)nn(-c3ccccc3)c2C)cc1F +OC(CNc1ccc(Cl)cn1)c1cccc(F)c1 +CC1CN(C(=O)Nc2cccc(F)c2F)CC(C)(C)O1 +CNc1snc(C)c1C(=O)OC(C)C(=O)Nc1ccccc1OC +Cc1ccc(N)c(Oc2nccn(C(C)C)c2=O)c1 +Cc1noc(C)c1CN1CC2(CCN(c3nncs3)C2)CC1=O +CCC(C)C(NC(=O)CCn1ncc(=O)c2ccccc21)C(N)=O +Cc1nc(C)c(C(C)NC(=O)Nc2ccccc2Cl)s1 +N#Cc1ccccc1NC(=O)CCCC(=O)N1CCCCC1CCO +COCCNC(=O)c1csc(-c2ccccc2OC)n1 +N#CC(NCc1ccco1)c1ccc(Cl)cc1Cl +O=S(=O)(CCOc1ccc(F)cc1)NCc1ccncc1 +COc1ccc2c(c1)nc(C(C)C)n2Cc1cccnc1 +CCc1ncc(NC(=O)Cc2cccc(OCC#N)c2)cn1 +Cc1cc(Cl)cc(Cl)c1-n1ncc(C#N)c1N +Cc1nc(Cc2c(C)noc2C)n(-c2ccc(C(F)(F)F)cc2)n1 +CN(C(=O)c1ccccc1)c1cccc2ncccc12 +Cc1ccc(OCCCOc2cccnc2N)cc1 +CC(C)CNC(=O)C1CCN(c2ccccc2F)CC1 +COc1cc(CNC(=O)Nc2ncc(-c3ccccc3)s2)ccn1 +O=C(CNS(=O)(=O)c1cccs1)Nc1ccc(Cl)cc1 +CN(C)C(=O)COc1cccc(NC(=O)Cc2ccccc2Cl)c1 +CCCC(=O)Nc1cccc(CNC(=O)N(C)Cc2cnn(C)c2)c1 +COC(=O)c1cccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)c1 +COc1cc(OC)c(C(=O)NCc2ccccc2C)cc1OC +Cc1ccc(C(=O)N(C)C(C)c2ccon2)cc1N1CCNC1=O +O=C(NC1CCCC2OCCC12)N(CC(O)c1ccccc1)C1CC1 +N#Cc1ccccc1CSc1nnnn1C1CC1 +CCNC(=O)c1ccc(OCc2cc(Cl)c3c(c2)OCCO3)cc1 +CCOC(=O)c1[nH]c(=O)[nH]c1CN1CCCc2ccccc21 +CCCCNS(=O)(=O)c1cn(C)c(=O)n(C)c1=O +CNC(=O)c1sc(-c2cc(Br)ccc2OC)nc1C +COc1cccc(-c2csc3[nH]c(-c4ccccn4)nc(=O)c23)c1 +COc1ccccc1OC(=O)Cn1cnc2sccc2c1=O +Cc1ccc(CNC(=O)NC2CCCN(c3ncccn3)C2)s1 +CC(C)c1cc(NC(=O)CNC(=O)c2cccs2)[nH]n1 +Cc1ccnn1CCNC(=O)C(C)Cc1cccs1 +Cc1cc(C(=O)N2CCOC(C)C2)ccc1-n1cnnn1 +COC(=O)c1ccccc1S(=O)(=O)Nc1ccccc1F +COc1cc(OC)cc(-c2nc(-c3cccnc3)no2)c1 +CC(C)c1nnc(NC(=O)c2ccc(-n3ccnn3)cc2)s1 +C#CCN1C(=O)c2ccccc2NC1C1=Cc2ccccc2OC1 +O=C(Cc1ccc(Cl)cc1)NCc1cnn(Cc2ccccc2)c1 +CCc1cc(=O)oc2cc(OCC(=O)NC(C)(C)C)ccc12 +CC(C)N(C(=O)c1ccc(OCC(F)F)nc1)C(C)C +COc1ccc(NC(C)=O)cc1NC(=O)c1cccn1C +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)N(C)Cc2cccs2)c1C +CNC(=O)C1CC(=O)N(c2cc(Cl)c(OC)cc2OC)C1 +N#Cc1ccc(-c2ccc3c(c2)OCO3)nc1N1CCCC1 +CC(C)CCC(=O)N1CCN(c2ccccc2C#N)CC1 +Cc1cc(C)cc(NC(=O)CCC(=O)N2CCOCC2)c1 +COc1ccc(Br)cc1NCc1nc(C2CC2)no1 +Clc1ccc2c(c1)C(C=Cc1ccncc1)NCC2 +CC(=O)c1c(Nc2cc(C)cc(C)c2)oc(C)cc1=O +Cc1nc2ccccc2c2c1Cn1c(C)nnc1S2 +CC(=O)N(C)c1cccc(NC(=O)NC2CCOCC2)c1 +N#CCCSc1ccccc1NC(=O)CSc1ccc(F)cc1 +CC1CCCN(C(=O)c2sccc2-n2cccc2)C1 +CC(=O)N1CCC(C(=O)Nc2ccc(OC(F)(F)F)cc2)CC1 +Cc1ccc(S(=O)(=O)Nc2cccc(C(=O)NC3CC3)c2C)cc1 +Cc1ccc(C2(Cc3ccccc3F)NC(N)=NC2=O)o1 +Cc1ccc(OCC(C)NC(=O)Nc2nncs2)cc1 +O=C(CSc1ccncc1)OCc1nc2ccccc2s1 +C#CCNC(=O)c1cccnc1Nc1cccc(F)c1 +Cn1nnc2c(N3CCN(CC(=O)NC4CCCC4)CC3)ncnc21 +COc1ccc(-n2nc(C)c3c(C)cc(=O)oc32)cc1 +COC(=O)N1CCc2ccc(F)cc2C1C(=O)NC(C)(C)CO +O=C(C1CCOc2ccccc2C1)N1CCC(c2cc[nH]n2)CC1 +COC(=O)c1ccc(-n2[nH]c(-c3ccccc3)cc2=O)cc1 +CC(=O)c1cccc(NCC(=O)c2cccc(N)c2)c1 +Oc1ccc(C2NCCc3ccc(O)c(F)c32)cc1 +COc1cccc(C(=O)Nc2ncccc2C)c1OC(F)F +Cc1ccc(NC(=O)Cc2nc(-c3ccccn3)n[nH]2)cc1C +Nn1c(Nc2ccccc2)nnc(C=Cc2cccs2)c1=O +Cn1cc(S(=O)(=O)NC2(C)CCCC2)c(=O)n(C)c1=O +Nc1[nH]nc(CCc2ccco2)c1-c1cccs1 +CC(C)CN(CC(F)(F)F)C(=O)CCn1nc2ccccn2c1=O +CCCCC(=O)N1CCN(c2ccccc2O)CC1 +Cc1noc(C)c1CC(=O)N1CC(c2nc3ccccc3[nH]2)C1 +CC(C)Cn1cc(C(F)F)c(C(=O)Nc2cccc3[nH]cnc23)n1 +CC(=O)NC1C(=O)N(CCOc2cccc(C)c2)c2ccc(C)cc21 +O=S(=O)(Nc1ccccc1O)c1ccccc1F +CS(=O)(=O)N1CC2CN(c3nncs3)C2C1 +COCC(=O)N1CCC(C(=O)N2CCCC2c2nccs2)CC1 +CCc1nc(CNc2ccc(Cl)cc2F)no1 +CCC(C)C(=O)Nc1ccc(CN2CCOCC2)cc1 +COC(=O)C(NC(=O)C#Cc1ccccc1)c1ccc(Cl)c(F)c1 +Cc1ccc(NS(=O)c2ccc(N)cc2)c(C)c1 +CCCCS(=O)(=O)N1CCN(C2CCCCC2)CC1 +CC(Cn1c(=O)oc2ccccc21)NC(=O)c1nccc2ccccc12 +CCC(c1nc2ccc(OC)cc2[nH]1)N1CCOCC1 +CCOC(=O)CN(CC)C(=O)c1cc(SC)ccc1Cl +CCCNC(=O)NCc1cccnc1OCC(F)(F)F +NC(=O)c1ccc(F)c(NCC2CCC=CO2)c1 +Nc1oc2c(c1C(=O)c1ccccn1)C(=O)CCC2 +CN(Cc1cccc(F)c1)C(=O)CSc1nnnn1C1CC1 +NC(=O)N1CCC(C(=O)NCc2ccccc2Cn2cccn2)CC1 +Cc1cc(CNC(=O)Nc2nc(C(F)(F)F)cs2)on1 +COc1cc(C(=O)NCc2nccc3ccccc23)ccc1C +Cc1cc(C)c(C(=O)CCCC(=O)Nc2cc(C)n[nH]2)c(C)c1 +CCc1ccc(C(=O)NCc2ccccc2OC)cc1 +CCOC(=O)c1nnn(Cc2ccc(C)cc2)c1N +N#CC1(NC(=O)CCc2ccccc2OC(F)(F)F)CCC1 +O=C(CNc1ccc(-n2cccn2)cc1)Nc1ccccc1Cl +CCCC(C)C(=O)NCC(=O)N1CCCc2ccccc21 +FC(F)Oc1cccc2c1C(c1ccc[nH]1)NCC2 +Cc1cnc(C(=O)N(C)Cc2ccc3ccccc3c2)cn1 +Cc1c(C(=O)NCC2CN3CCCC3CO2)sc2cccc(F)c12 +CN(Cc1ccco1)C(=O)CSc1ccccc1Cl +CCOC(=O)c1ccc(N2CCC(C(N)=O)CC2)nc1 +CC(C)CC(C)OC(=O)c1ccc(C(=O)N(C)C)cc1 +CNC(=O)c1cccc(C(=O)OC2CCCC2n2cccn2)c1 +CC(=O)N1Cc2ccccc2CC1C(=O)N1CCc2cnccc21 +O=C(Nc1nncs1)c1cc2cc(Cl)ccc2o1 +CCCS(=O)(=O)NCCn1nc(-c2cccs2)ccc1=O +COc1ccc2cc(C(=O)N3CCOCC3(C)C)[nH]c2c1 +CCOC(=O)c1nn(-c2ccc(C(F)(F)F)cc2)c(N)c1C +O=C(COC(=O)Cc1ccsc1)Nc1ccc2c(c1)OCO2 +NC(=O)NCCC(=O)NCc1ccc(Br)cc1Cl +Cc1noc(C)c1CNC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +Cc1ccc(C(=O)N(CCC#N)c2ccccc2)c(O)c1 +CN1CC(C(=O)N(C)Cc2cccc3ccccc23)CC1=O +Cc1cc(C)n(C(C)C(=O)N2Cc3cnc(-c4ccccc4)nc3C2)n1 +Cc1coc(-n2ccc3nccc(Br)c32)n1 +Nc1ccc(C(=O)Nc2cc(Br)ccc2F)cc1 +CC(Sc1ccccn1)C(=O)NC(C)(C)c1nccs1 +CCOCC1CCCN(C(=O)c2cc3cc(C)ccc3nc2C)C1 +NC(=O)c1cccc(NC(=O)c2cccc(-c3ccoc3)c2)c1 +O=C(C(OC1CCCC1)c1ccccc1)N1CCN(CCO)CC1 +CC(=O)NCCCCCC(=O)Nc1nc2ccc(Cl)cc2s1 +O=C(CCc1ccco1)NC1CCCN(c2ncccn2)C1 +CCc1nn(C)c(CC)c1CNc1cnn(CC(F)F)c1 +CC1CN(C(=O)c2scnc2C2CC2)c2ccccc21 +O=S(=O)(NCc1cccs1)c1ccc2c(c1)OCCCO2 +Cc1ccc(S(=O)(=O)NCC(C)(O)c2ccc3c(c2)OCO3)cc1 +Nc1ccc(NC(=O)Nc2ccc(Cl)cc2)nc1 +Cc1nnnn1-c1ccccc1C(=O)NCc1cccc(Cl)c1 +O=C1Nc2ccc(F)cc2C1NCCN1CCOCC1 +Cc1ccccc1COC1CCN(C(=O)NCC2CC2)CC1 +Cc1nccn1-c1cc(CNc2nnnn2-c2ccccc2)ccn1 +Cc1occc1C(=O)NCC(=O)N(C)C(C)CC(C)C +Cc1ccc(C(=O)N(CCC#N)CCC(F)(F)F)c(F)c1 +COc1cccc(OC)c1COC(=O)c1cnn(C)c1C +Cc1ncc2c(n1)CN(c1nccc(C(F)(F)F)n1)CC2 +N#CCCCOc1cccc(CNc2ccc3[nH]ncc3c2)c1 +O=C(NCCC(=O)N1CCCC1c1ccncc1)NC1CCCCC1 +COCCn1c(SCC#N)nnc1-c1ccc(Cl)cc1 +N#Cc1nn(-c2ccc(F)c(F)c2)c2c1CNCC2 +COC(=O)C(NC(=O)c1cc(Br)cn1C(C)C)C(C)C +Cc1noc(C)c1C(C)NC(=O)NC(C)CCc1ccccc1 +NC(=O)N1CCC(NC(=O)Nc2cc(Cl)ccc2Cl)CC1 +COc1ccc2[nH]c(C(=O)NCc3ccc4c(c3)OCO4)cc2c1 +Fc1ccccc1-c1noc(CCc2nc(C3CCOC3)no2)n1 +CC1CNc2cc(CCNCc3ccco3)ccc2O1 +CNC(=O)c1ccc(CNc2cc(C)nc(-c3ccncc3)n2)cc1 +Cc1ccc(OCC#CCNC(=O)Cn2ccc3ccccc32)cn1 +CC(C(=O)NCCc1ccccc1)n1nc(-c2ccccc2)ccc1=O +CC1CCN(C(=O)NCc2noc3ccccc23)CC1 +COc1ccc(CNC(=O)CCc2ccccc2N)cc1 +Cc1ccc(S(=O)(=O)CCC(=O)N2CCOCC2)cc1 +Cc1nc(C2(NC(=O)Nc3cnccc3C)CCCC2)no1 +CC(C)C(NS(=O)(=O)c1ccccc1)c1nnc2ccccn12 +O=C(CSc1nc(-c2ccccc2)n[nH]1)Nc1ncccn1 +CCc1nc(CNCCc2ccc(-n3cccn3)cc2)cs1 +COc1cc(C#N)cc(Cl)c1OCC(=O)NC1CCCC1 +CC(C)(C)n1nnnc1SCc1ccc(OCC(F)(F)F)nc1 +O=C1COc2ccc(S(=O)(=O)CCC(=O)NC3CC3)cc2N1 +Cc1c(-c2nnc(-c3ccccn3)o2)oc2ccccc12 +COC(=O)CCN(C)C(=O)c1cc(F)cc(Br)c1 +CCc1ccc(NS(=O)(=O)c2ccc(-n3cccn3)cc2)cc1 +O=C(COc1ccc2c(c1)CCC2)NCc1csc(=O)[nH]1 +COc1cc(CNC(=O)C(C)NC(=O)Nc2ccccc2)ccn1 +Cc1oc(S(N)(=O)=O)cc1C(=O)NC1CCN(c2ccccc2)C1 +O=C(NC1CCC(O)CC1)N1CCN(C(=O)C2CCCCC2)CC1 +O=C(NCC(O)c1ccccc1)NC1CCCCC1 +CCCOc1cc(S(=O)(=O)NC(C)C)ccc1Cl +CCOc1ncc(C(=O)N(C(C)C)C2CCC2)cc1Cl +CCOc1ccc(Cl)cc1S(=O)(=O)Oc1ccccn1 +CCc1nc(NC(=O)C2CC(=O)N(C3CC3)C2)sc1C +Cc1nc(C2CCCN(C(=O)C(C)Cc3c(C)noc3C)C2)no1 +Cc1[nH]c2ncnc(NC(=O)C3OCCc4ccccc43)c2c1C +Cc1ccc(-c2nnc(CN3CCc4ccccc43)o2)cc1 +O=C1CCCc2cc(OC3CCN(c4ccccc4)C3=O)ccc21 +CN(C)C(=O)c1ccc(CNC(=O)NC2CCCCC2)cc1 +O=C(Cn1c(=O)[nH]c2ccccc21)OCc1coc(-c2ccccc2)n1 +Cc1cc(C(=O)NCC(C)(O)c2ccc(F)cc2)c2cnn(C)c2n1 +CC(=O)NCC1CCC2(CCN(c3ncc(C)cn3)CC2)O1 +CC(C)CN(CC(C)C)S(=O)(=O)c1ccc(N)nc1 +CNC(=O)c1ccc(Cl)c(NCc2csc(C)n2)c1 +N#CCCN(Cc1ccco1)C(=O)Nc1cccc2cccnc12 +NC(=O)C1CCN(C(=O)NCC2COc3ccccc3O2)CC1 +CCc1cccc(C)c1NC(=O)c1ccc(S(C)=O)cc1 +O=C(CS(=O)(=O)c1ccc(F)c(F)c1)NCc1ccccc1 +CCOCC1CCCN(C(=O)C(OC)c2ccccc2)C1 +CCc1ccc(CN(C)C(=O)c2ccccc2F)cc1 +CC(=O)N1CCc2cc(S(=O)(=O)NC(C)C#N)ccc21 +O=C1CC(C(=O)N2CC(c3ccccn3)C2)CN1Cc1ccccn1 +COc1ccc(C)cc1N1CC(C(=O)N=c2sccn2C)CC1=O +N#Cc1ccc(NC(=O)Cc2ccc(Br)cc2)cc1 +Cn1c(SCC(N)=O)nnc1-c1ccc2c(c1)OCO2 +NC(=O)c1ccc(NCC(=O)Nc2cccc(F)c2)cc1 +O=C(NCC(=O)N(Cc1ccc(F)cc1)C1CC1)c1cccc(F)c1 +CN(C)S(=O)(=O)c1ccc(OCC(=O)NC(C)(C)C)cc1 +CCCOC(=O)c1ccccc1SCC(N)=O +Cn1c(=O)c2ccccc2n2c(SC3CCCC3)nnc12 +COC(=O)C(C)(C)NC(=O)c1cc(-c2cccs2)n[nH]1 +CN(C(=O)CC1(CC(=O)N(C)C2CC2)CCCCC1)C1CC1 +O=C(Nc1ccc(-c2c[nH]cn2)cc1)C1COCCO1 +Cc1[nH]c2c(Cl)cc(Cl)cc2c(=O)c1CC#N +Cc1cccc(CNC(=O)CCC(=O)c2ccc(F)c(F)c2)n1 +Cc1noc(C)c1CNC(=O)NC1c2ccccc2CC1O +COc1ccc(C)cc1NCC(=O)Nc1ccccc1 +O=C(CSc1nc(C2CC2)n[nH]1)c1ccc(F)cc1 +CCn1cc(C(=O)Nc2ccccc2-n2nc(C)nc2C)cn1 +Cc1cnc(C)c(NCc2ccc3c(c2)OCO3)n1 +CC(=O)c1ccccc1OCCn1cnc(C#N)n1 +NC(=O)c1ccccc1OCC(=O)Nc1ccc(Cl)cc1F +CN(Cc1nccn1C(F)F)C(=O)c1ccc(O)c(Cl)c1 +COCCCCCNC(=O)N1CCOCC1c1ccc(C)o1 +Cc1ccsc1CNC(=O)CCC(=O)c1ccccc1 +COc1cc(NC(=O)Nc2cc(F)ccc2OC)cc(OC)c1 +Cc1ccc(NC(=O)NCC2CCOC2)cc1Cl +CCN(CC)C(=O)CN1C(=O)C(C)Oc2c(N)cccc21 +CCn1c(=O)n(CC(O)=NCc2ccco2)c(=O)c2ccccc21 +O=C(Nc1ccccc1)Nc1ccc(-n2cc(Cl)cn2)cc1 +CC(C)(C)C(=O)NCCN1CCN(c2ccc(F)cc2)CC1 +CCC1CCC(NC(=O)N2CCN(c3ncccc3C#N)CC2)CC1 +O=C(NCCS(=O)(=O)N1CCNCC1)C1CCCO1 +c1csc(-c2nc(N3CCc4cncnc4C3)c3ccccc3n2)c1 +CCOC(=O)CCC(C)NC(=O)c1cccs1 +CC(=O)NC(Cc1ccccc1)C(=O)N1CCNCC1 +O=C(c1nnc2sc(-c3ccccc3Cl)nn12)N1CCCCC1 +Cc1ccc(-c2nnc3c4cnn(C)c4ncn23)cc1 +CCn1c(SCC(=O)Nc2cc(C)on2)nc2ccccc2c1=O +COCC(=O)NC1CCOc2c(C)cc(C(O)C(C)C)cc21 +CNC(=O)Cn1cc(NC(C)c2ccccn2)cn1 +CC(C)C(C)N(C(=O)c1ccc(-c2cscn2)cc1)C1CC1 +CCCNC(=O)C1CCCCN1S(=O)(=O)c1ccccc1 +COc1ncccc1NCc1cc(F)cc(F)c1 +CCS(=O)(=O)N1CCN(c2ncc(Br)cn2)CC1 +COc1ccc(NC(=O)NCCNC(=O)NC2CCCCC2)cc1 +COc1cccc(C2CN(Cc3cc[nH]n3)CCO2)c1 +CC(C)CC(O)CNC(=O)N(Cc1ccco1)c1cccnc1 +COC(=O)c1cc2occc2n1CC(=O)Nc1ccccc1OC +COc1cc(NC(=O)c2cc(C)ccc2C)ccc1NS(C)(=O)=O +CC1(C)OC(=O)C(C(c2ccccc2)C(C#N)C(N)=O)=C(O)O1 +COc1ccc(Cl)cc1CNc1ccc(S(N)(=O)=O)cc1 +CCc1nc(C)sc1CNc1nccc(-c2cccnc2)n1 +Cc1cc(NC(=O)CCn2cncn2)c2ncccc2c1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NC(C)c2ccccc2)[nH]n1 +CC(NC(=O)Cc1cccc(F)c1)C(=O)N1CCCC1 +COc1ccc(CNc2ccn(C)n2)cc1CN1CCOCC1 +Cc1nc(C)c(COC(=O)c2ccc(CCNC(N)=O)cc2)s1 +COc1ccc2nc(SCc3ccc(C(=O)N(C)C)cc3)[nH]c2c1 +CN(Cc1n[nH]c2c1CCCC2)C(=O)Nc1nnc(C2CCC2)s1 +COc1cccc(NC(=O)c2csc(-c3cnccn3)n2)c1 +CCC1CCCCN1S(=O)(=O)c1cc2c(cc1C)NC(=O)CO2 +COc1ccc(C(=O)Nc2ccc(OCc3nccn3C)cc2)cn1 +C=CCN(Cc1ccccc1)C(=O)Nc1ccc(C)c(-n2cnnn2)c1 +CC(NC(=O)C1CCOCC1)c1cccc(Cl)c1 +NC(=O)C1CCN(C(=O)c2ccc(-c3cccc(Cl)c3)s2)CC1 +CC(C)S(=O)(=O)c1ccc(NCC(=O)N(C)C)cc1 +CNC(=O)N1CCC2(CC1)CN(C)c1c(F)cccc12 +COc1ccc(C(=O)Nc2ccccc2F)c(OC)c1OC +Nc1onc(-c2cn[nH]c2)c1-c1c(F)cccc1Cl +COCCN1CC(c2cc(=O)[nH]c(N3CCC(C)CC3)n2)CC1=O +Nc1ccc(F)cc1CSc1nccc(=O)[nH]1 +Cc1cccc(Cl)c1NC(=O)Cn1nnc2c(cnn2C)c1=O +Cc1nc(C(=O)NC2=NC(=O)N(C)CC2)cs1 +O=c1c2ccccc2nnn1-c1cccc(Cl)c1 +CS(=O)(=O)N(CC(=O)NCc1ccncc1)c1ccccc1 +Cc1cc(NC(=O)COc2ccc3c(C)c(C)c(=O)oc3c2)no1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)N1CCC2CCCCC2C1 +Cn1ncc(C(=O)Nc2nc(C3CC3)cs2)c1-n1cccc1 +CN(C)C(=O)CN(C)C(=O)c1cccc(OCC2CCCO2)c1 +Cc1[nH]c2ccccc2c1C(=O)NC1CCC(C)CC1 +Cc1ccc(-c2n[nH]cc2CN2CCOC(c3nccs3)C2)cc1 +Cc1nn(C)cc1C(=O)Oc1cccc(-n2cccn2)c1 +COc1ccc2ccc(OCc3nc(N)nc(N(C)C)n3)cc2c1 +C=CCN(Cc1ccccc1C)C(=O)c1cc(=O)c2ccccc2[nH]1 +c1ccc(CN2Cc3ccnn3CC(COCc3cccnc3)C2)nc1 +COc1ccc(-c2noc(CNc3ccc(-n4cccn4)cc3)n2)cc1 +COc1ccc(F)cc1NC(=O)c1sccc1C#N +O=C(COC(=O)c1ccco1)NC1c2ccccc2-c2ccccc21 +CN(Cc1cc(Br)cn1C)C(=O)C1CC2C=CC1C2 +CC(C)c1cc(C(=O)Nc2cccc(N3CCCS3(=O)=O)c2)n[nH]1 +Cc1cccc(NC(=O)c2csc(NCC(C)C)n2)n1 +CC1CCN(C(=O)NCCN(C)c2ccccc2)CC1 +CC(Oc1ccc(C(N)=O)cc1)c1nc(-c2cccs2)no1 +COc1ccc(CNS(=O)(=O)N2CC(C)CC(C)C2)cc1OC +COC(=O)c1ccccc1SCc1nnc(C2CC2)o1 +COc1ccccc1-c1cn(-c2cc(N)ccc2C)nn1 +CC(C)(C)c1nnc(SCC(=O)Nc2cccc(Cl)c2)n1N +O=C(OCc1ccccc1)N1CCn2c(c[nH]c2=O)C1 +CCCN1CCN(C(=O)c2ccn3c(-c4ccccc4)nnc3c2)CC1 +O=C(c1cccnc1Nc1ccccc1F)N1CCOCC1 +O=c1c2cccn2cnn1CCCOCc1ccccc1 +CNC(=O)NC(C)(C)C(=O)NCc1ccc(C)s1 +COc1ccc(CN(C2CC2)S(C)(=O)=O)cc1 +O=C(Nc1ccc(Br)cc1O)C1CC=CC1 +Clc1ccc(C2=Nn3c(nnc3-c3ccncc3)SC2)cc1 +CC(C)Cn1ccc2cc(NC(=O)NC(C)c3ccncc3)ccc21 +Cc1ccc(C)c(NC(=O)c2cc(-c3ccncc3)[nH]n2)c1 +N#Cc1cccc(CN2CCN(C(=O)c3cccc(F)c3)CC2)c1 +Cc1cccnc1NC(=O)CNC(=O)c1ccc(F)c(F)c1 +O=C(C1CCOC1)N1CCCn2c(nc(CN3CCCC3)cc2=O)C1 +CC1Cc2ccccc2N1C(=O)NCc1ccc(C(=O)N(C)C)cc1 +CN(C)C(=O)COC1C2CCCC1CN(c1nncs1)C2 +Cc1ccc(-n2nnnc2SCc2c(C)noc2C)c(C)c1 +CCOc1ccc(-c2cn[nH]c(=O)c2CO)cc1F +NC(=O)CC1CCN(C(=O)c2cccnc2SC(F)F)CC1 +CCN1CCN(S(=O)(=O)c2ccc(C(C)(C)C)cc2)CC1 +CCc1nccn1-c1cccc(C2CCCN(Cc3ccccn3)C2)n1 +CCCn1nc(C(=O)NC(C)C2CCCO2)ccc1=O +CC(=O)NC(c1nc(C)nn1Cc1cccc(C)c1)C(C)C +COc1ccc(CNc2ccc(F)cn2)cc1F +CCOC(=O)c1cnc(SC)nc1NCc1ccccc1 +O=C(NC1CCCC1)c1cc(-c2ccncc2)[nH]n1 +Cc1cccc(NC(C(=O)N(C)C)c2ccccc2)c1C +NC(=O)C(NC(=O)c1sc2ccccc2c1Cl)c1ccccc1 +CCC(C)C(NC(=O)NCc1ccc2c(c1)OCO2)C(=O)OC +CNc1nc2ccccc2nc1N1CCCC1CO +O=C(NCc1ccccc1)c1ccccc1N1CCCC1=O +C=CCCC(=O)NCC#Cc1ccc(N2CCCCC2=O)cc1 +Cc1ccc2c(c1)SC(C(=O)N(C)Cc1cnn(C)c1)C2 +CC(C(=O)NCc1nnc2n1CCCCC2)n1cccn1 +NC(C(=O)Nc1ccc2c(c1)CCN2C(=O)C1CC1)c1ccccc1 +NC(=O)c1[nH]nc2c1CCOc1cc(Cl)c(Cl)cc1-2 +CCN(CC)C(=O)COc1ccc2c(C)c(C)c(=O)oc2c1C +CC(C)Cn1cc(NCc2c[nH]nc2-c2cccs2)cn1 +CN(C)C(=O)Cc1ccc(-c2cccc(C#N)c2)cc1 +CCNC(=O)c1ccc(-c2ccc(F)cc2F)nc1N +Cc1ccc(S(=O)(=O)N(C)CCOCC2CC2)cc1 +O=C(c1ccncn1)N1CCOC2C(OCc3ccncc3)CCC21 +CCN(Cc1ccccc1Cl)C(=O)c1csc(NC(C)=O)n1 +Cc1cc(C)nc(Nc2nc(-c3ccccc3N)n[nH]2)n1 +Cc1cc(F)ccc1NC(=O)c1cc(F)cc2[nH]cnc12 +CC(C)C(NC(N)=O)C(=O)N1CCN(c2ccccc2F)CC1 +CCn1c(SCC(=O)N2CCC(C(N)=O)CC2)nc2ccccc21 +COc1cccc2cc(C(=O)Nc3ccc4c(c3)CC(=O)N4C)oc12 +CCOCCCNC(=O)Cn1c2ccccc2c2nc(=O)cc(C)n21 +O=C(NCCC(=O)N1CCCCC1)C1CC1c1cccc(Cl)c1 +O=C1NCc2ccc(NCc3c[nH]nc3-c3ccccc3F)cc21 +Cn1c(=O)c2[nH]c(-c3cccnc3)nc2n(C)c1=O +CCC(CO)NC(=O)Nc1cccc(-c2nnco2)c1 +Cc1nn(-c2ccccc2)c(C)c1CC(=O)NC1(C#N)CCCCC1 +CC(C)N(C(=O)CSc1nc2ncccn2n1)c1ccccc1 +COc1ccc(SCC(=O)Nc2sc(C)c(C)c2C#N)cc1 +CS(=O)(=O)c1ccccc1C(=O)NCCc1c[nH]c2ccccc12 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)Nc2cc(C)on2)c1 +CC(C)(C)c1ccc(OCc2ncc(N)cn2)cc1 +Cc1cc(F)ccc1S(=O)(=O)NCC(O)C1CCCCC1 +CCCn1nccc1C(=O)Nc1nc2ccccc2n1C +CCCCn1c(SCc2noc(-c3ccccc3)n2)n[nH]c1=O +Cc1nc(CNC(=O)Nc2cc(C(F)(F)F)ccc2F)c(C)s1 +CCC1=C(C(=O)OC)C(c2cccnc2)NC(=O)N1 +CC(C)(C)c1ncc(CNC2CCCCNC2=O)s1 +CC(=O)c1ccc(OCC(=O)Nc2ccccc2SCC#N)cc1 +Cc1cc(C(=O)CSc2nccn2C)c(C)n1CCC(C)C +CCCN(CC1CC1)C(=O)Nc1ccc(N2CCOC2=O)cc1 +Cc1nn(CC(=O)OC(C)C)c(C)c1CN1C(C)COCC1C +Cc1ccc(C(=O)NCc2nc(-c3cccs3)no2)cc1C +COC(=O)Nc1cc(N2CCCS2(=O)=O)ccc1C +CN(C)C(=O)C(Cc1ccccc1)NC(=O)NC1CCCCCC1 +CCOc1ccccc1OCC(=O)NCc1ccco1 +Clc1ccc(CSc2nnc(C3CC3)n2Cc2ccco2)nc1 +CC(=O)Nc1cc(NC(=O)NC2(C)Cc3ccccc3C2)ccc1C +Cc1nc(-c2ccsc2)sc1C(=O)NCCc1cccnc1 +CC(C)C(C)NC(=O)NCc1cn(-c2ccccc2)nn1 +COC(=O)c1ccc(CN(C)Cc2c(C)nn(C)c2OC)cc1 +CC(=O)c1ccc(S(=O)(=O)N2CCc3ccc(Cl)cc3C2)cc1 +Cc1ccc(-c2ccnc(NCCOC(C)C)n2)c(C)n1 +COc1ccc2c(c1)C(C1COc3ccccc3O1)NCC2 +c1cnc(-c2nc(-c3nc(-c4cc5ccccc5o4)no3)cs2)nc1 +Cc1n[nH]c(C)c1N1CCN(C(=O)CSc2ccc(F)cc2)CC1 +Cn1c(CNS(=O)(=O)c2ccccc2F)nc2cccnc21 +O=C(Nc1c(F)cccc1F)N1CCc2cc(F)ccc2C1 +CC(NC(N)=O)C(=O)NC(C)c1ccc(OCC(F)(F)F)cc1 +CC(C)Sc1nnc(C2CCCN2C(=O)OC(C)(C)C)o1 +CC(C)Oc1ccc(OCCN2CC(C)OC(C)C2)cc1 +COCCc1n[nH]c(N)c1-c1nc2ccccc2s1 +Cc1nn(C)c2[nH]c(-c3cnn(-c4ccc(Cl)cc4)c3)nc12 +Cc1c(-c2ccnn2C(=O)c2cccs2)cnn1-c1ccccc1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc[nH]2)CC1 +Cc1cc(C)n(CC(=O)Nc2cccc(C(C)C)c2)c(=O)c1C(N)=O +O=C(CN1CCN(c2ncccn2)CC1)Nc1cccnc1 +O=S(=O)(CCCc1nc(-c2cccs2)no1)c1ccccn1 +O=C(c1c[nH]nc1-c1ccc(F)cc1)N1CCOCC1 +Cc1c(NC(=O)c2ccccc2)cccc1NC(=O)C(C)C +CC(OC(=O)c1ccc(-n2cnnn2)cc1)C(=O)N1CCCC1 +COc1ccc(NC(=O)NC2CCN(CC(F)(F)F)C2)cc1C +N#Cc1cc(S(=O)(=O)Oc2ccc3ccc(=O)oc3c2)ccc1F +COCCNC(=O)c1ccc(N(C)Cc2ccc(C)s2)nc1 +CC(=O)N1CCN(C(=O)c2cccc3[nH]ccc23)CC1 +OCc1cccc(NCc2c(F)cc(F)cc2F)c1 +CNC(=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1Cl +O=C(NCc1ccon1)Nc1nnc(CCN2CCOCC2)s1 +Cc1cc(C(C)NC(=O)NCC(=O)NCC2CC2)cc(C)c1F +COC12C=CC(C=C1)c1c(F)c(F)c(F)c(F)c12 +COC(=O)c1oc(CSc2ncc3ccccn23)cc1C +Cn1ccc(NC(=O)c2ccc(NC(=O)c3ccco3)cc2)n1 +CCCNC(=O)CNC(=O)N1CCCC1C1CCCC1 +COc1cc(NCC(=O)Nc2ccccc2C)ncn1 +CC1CCN(C(=O)c2cnc(-c3ccccc3)nc2N(C)C)CC1 +C#CCNC(=O)COc1ccc(F)cc1Br +NS(=O)(=O)c1cc(NC(=O)c2cnccn2)ccc1Cl +Cn1c(=O)oc2c(C(=O)NCC3CN4CCCCC4CO3)cccc21 +Cc1cccc(C(C(=O)N2CC(n3nc(C)cc3C)C2)N(C)C)c1 +CC(C)CCn1cnc2c(nnc3ccnn32)c1=O +CCOc1cccc2c1C(c1ccncc1F)NCC2 +CCOc1ccc(CCN2CCN(c3ncccn3)CC2)cc1N +COCCOC(=O)C1CCCC(C(F)(F)F)C1 +COc1ccc(NC(=O)NCCNc2nc(C)cc(=O)[nH]2)c(OC)n1 +COc1cc(CO)cc(Br)c1OCC#N +N#Cc1ccc(N2CC3OCC(=O)N(CC4CC4)C3C2)nc1 +C=CCn1c(=O)oc2ccc(C(=O)N3CCCCC3)cc21 +Cc1cccc(CNC(=O)CCCN2C(=O)CCn3nc(C)cc32)c1 +CCC(NCc1cc(=O)c2c(C)ccc(C)c2[nH]1)c1cnn(C)c1 +Cc1nnc(Cn2cnc3sc4c(c3c2=O)CCCC4)o1 +O=C(Nc1cccs1)N1CCC(c2nnc(-c3ccco3)o2)CC1 +CC(C)(CNC(=O)CCc1ncc(-c2ccccc2)o1)c1ccncc1 +CC1COC(Cn2cncn2)(c2occ3ccccc23)O1 +O=C(Cn1cnc2sccc2c1=O)NCCOc1ccccc1 +COC(=O)c1cnn2c1nnc1c(=O)n(-c3ccc(C)cc3)ccc12 +COCCN1CCOC2CC(COCc3ccccn3)CC21 +N#Cc1c(-c2ccncc2)cc(-c2c[nH]c3ccccc23)nc1N +Cc1c(C(=O)NCC2CCC(C)(C)CC2)sc2ncn(C)c(=O)c12 +Cc1ccc(C(=O)N2CC3CC(NC(=O)c4cccnc4)C2C3)cn1 +CCN1CC(c2nc3ccccc3n2Cc2ccc(C)cc2)CC1=O +Fc1ccc(CN2CCC(c3nnc(-c4ccncc4)o3)C2)cc1F +CCC1CCCN1C(=O)c1ccc(OC)c(Br)c1 +Cc1cc(C)c(NC(=O)Cc2c[nH]c3ccccc23)c(C)c1 +CCC(Nc1cnc(C(N)=O)cn1)c1cccs1 +CC1CN(C2CCN(Cc3cccc4[nH]ccc34)CC2)CCO1 +CCC(CO)N1CCN(C(=O)Nc2ccc(S(C)=O)cc2)CC1 +O=C(NCc1ccc(-n2ccnc2)nc1)c1cc2ccccc2o1 +CC(C)CNC(=O)COc1cc(F)ccc1C(C)O +CCC(NS(=O)(=O)c1cccc(C(C)=O)c1)c1nccs1 +Cc1csc(=O)n1CCC(=O)NCc1ccccc1F +Cc1ccc(C2CC(C(F)F)n3ncc(C#N)c3N2)cc1 +O=C(OCn1nnc2ccccc2c1=O)c1ccc(O)cc1 +Cc1noc(C)c1C(C)NC(=O)c1ccc(Cl)cc1O +CCN(CC)C(=O)c1ccc(-n2nc(C)cc2C)cc1 +COC(=O)C1CCCc2c1cnn2CC(=O)Nc1ccc(C)cc1 +CS(=O)(=O)Nc1cc(NC(=O)c2cccc(F)c2)ccc1F +c1cc(CNc2nnc(C3CC3)o2)cc(-n2cccn2)c1 +CCOC(=O)c1cnc2cc(C)nn2c1C(F)(F)F +O=C(CCC(=O)c1ccc(Cl)cc1)NCc1ccco1 +CN(CCc1ccncc1)C(=O)c1cc(N2CCNC2=O)ccc1F +Cc1cc(Cl)ccc1NC(=O)NCCNC(=O)c1ccc(O)cc1 +Cc1ccc(C(N)=O)cc1NC(=O)N1CCC(n2cccc2)CC1 +COCCS(=O)(=O)NC(c1ccc(F)cc1)C(C)(C)C +CCOC1CC(NC(=O)C2CCCN(CC(F)(F)F)C2)C1OC +CCCCn1nc(-c2cccnc2)cc(CO)c1=O +COc1cccc(-c2cn3ccn(-c4cccc(OC)c4)c(=O)c3n2)c1 +O=C(NCc1cccs1)C1COC2CN(c3ncccn3)CC21 +O=C(CCCC(O)c1ccccc1)Nc1ccc(F)cc1 +O=C1C(=O)N(Cc2cc3c(cc2Cl)OCO3)c2ccccc21 +CCc1ccc(CN(C(=O)C2CCC(=O)N2)C2CC2)cc1 +Cc1cc(NC(=O)C2CCCN(C(=O)NC3CC3)C2)sn1 +Cc1ccnc(NC(=O)c2c(C)oc3ncn(CC(C)C)c(=O)c23)c1 +Nc1nnc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)o1 +O=C(NCCCn1ccc2cccnc21)c1ccc(=O)oc1 +Cc1ccc(S(=O)(=O)N2CCC3(CC2)OCCCO3)s1 +O=S(=O)(c1cncc(F)c1)N(CCO)c1cccc(F)c1 +CC(C)Cc1ncc2c(n1)CN(C(=O)CCn1cnc3ccccc31)C2 +Cc1nn(C)c2oc(N)c(-c3ccccc3C(F)(F)F)c12 +Cc1ccccc1-c1cnnc(N2CCN(c3cnccn3)CC2)n1 +O=S(=O)(c1cc(F)cc(F)c1)N1CCCCC1C1OCCO1 +Cc1cn(Cc2ccc(Cl)c(Cl)c2)nc1N +Nc1nc2ccccc2n1C(=O)c1ccccc1F +CN(C(=O)c1cnn(-c2ccc(F)cc2)n1)c1nccs1 +Cc1cnn(C2CCCN(C(=O)C(OCC3CCCO3)C(C)C)C2)c1 +Cc1ccc(Cn2cc(NC(=O)c3cc4ccccn4n3)cn2)cc1 +CCc1cc(CNC(=O)CCc2c[nH]c3ccccc23)[nH]n1 +CNc1snc(C)c1C(=O)NCCc1cccc(Cl)c1 +COCCN(Cc1ccccc1)C(=O)c1ccc(SC)cc1 +Cc1ccc(CNC(=O)Nc2ccc(C)c(-n3cnnn3)c2)cc1 +COC(=O)CSc1nnc(-c2ccccc2Cl)n1N +Cc1nc(C(=O)N(C)Cc2ccc(O)cc2)cs1 +Cn1cc(C(=O)NCc2ccnc(-n3cccn3)c2)c(C(C)(C)C)n1 +CC(C)C(C)NC(=O)C1CCCCN1S(=O)(=O)c1ccccc1 +CCOC(C)c1nc(CN(C)Cc2cc(=O)c(O)co2)cs1 +CCOc1ccc(CC(=O)NCc2cccs2)cc1 +CCOC(=O)C(C)N1CCCC(c2nc3ccccc3n2C(C)C)C1 +CCNC(=O)CNc1ccc(C(=O)OC(C)(C)C)c(C)c1 +CCn1nc(C(=O)NC2CCCC2)cc1-c1ccc(OC)cc1F +O=C(Nc1nc[nH]n1)c1cc2ccccc2cc1O +N#CCn1ccnc1-c1ccccc1C(F)(F)F +O=C(CCc1ccco1)NCCc1cc(N2CCCC2)ncn1 +COc1ccc2c(c1)[nH]c(=O)n2Cc1ccccc1F +O=C(c1cncc(Br)c1)N(Cc1ccccc1F)C1CC1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2ccc3c(c2)OCCO3)n1 +CCC(=O)c1cccc(S(=O)(=O)NC(C)c2ncc(C)s2)c1 +Cc1ccc2nc(C)c(C(=O)OCCNc3cccnn3)cc2c1 +CCOc1cc(C#N)ccc1OS(=O)(=O)c1ccc(F)c(F)c1 +CCC(=O)Nc1ccc(C)c(NCc2nc(CC(C)C)no2)c1 +Cc1cc2c(=O)n(Cc3ccccn3)cnc2cc1F +Cc1noc(CCC(=O)Nc2ccccc2-c2nc3ccccc3[nH]2)n1 +O=C(c1ccco1)N1CCN(Cc2cnc3ccccn23)CC1 +CCCSc1nc2c(c(=O)[nH]c(=O)n2C)n1C(C)C +CCNC(=O)CSc1nncn1-c1ccccc1 +CCn1cnnc1SCC(=O)Nc1c(F)cccc1F +CCN(Cc1ccccc1)C(=O)CNC(=O)C(C)c1ccsc1 +COCC(NC(=O)c1cc(Cl)ccc1OC1CCCC1)C(N)=O +Cc1cccc(-n2cc(C(=O)Nc3ccc(-c4nnco4)cc3)nn2)c1 +O=C(Nc1ccc(CCN2CCOCC2)cc1)C1CCCC1 +CN(Cc1cnn(C)c1)C(=O)Nc1nncs1 +Cc1ncsc1CN1CCC(OC(C)(C)C)CC1 +C=CCNC(=O)c1cc(C)nc2c1cnn2Cc1cccs1 +O=S(=O)(c1ccccc1)N1CCN(c2cccc(Cl)c2)CC1 +O=C(CSc1cc(N2CCCCC2)ncn1)NCc1ccco1 +N#Cc1ccc(F)c(COCCCc2ccncc2)c1 +CCOC(=O)c1cnc2cc(OC(=O)c3ccccc3)nn2c1C +CCN(CC)C(=O)CCC(=O)Nc1ccc(Cl)cc1NC(C)=O +CC1CN(c2ccc(C(=O)NC(C)c3ccccn3)cn2)CC(C)O1 +Cc1ccc2c(c1)S(=O)(=O)N(C)C(c1ccccc1)=C2 +Cc1cccc(OCC(=O)NCc2cscn2)c1 +CCOC(=O)C1=C(C)C(C(=O)CSc2ccccc2F)=NC1C +CCN(CC)C(=O)Cn1c(C(C)C)ccc(C#N)c1=O +COc1ccc(C(O)CNCc2ccccc2)cc1OC +CC1CCCN(C(=O)COC(=O)c2ccc(O)cc2O)C1 +O=C1CC(C(=O)OCc2ncc(-c3ccccc3)o2)c2ccccc2N1 +Cc1nc2cc(C(=O)Nc3nnc(C)s3)ccc2[nH]1 +CCOC(=O)c1sc2ncn(C(CC)C(=O)OC)c(=O)c2c1C +CCc1sc(C(N)c2ccc(Cl)cc2)nc1C +Cc1ccccc1NC(=O)C1COc2ccccc2O1 +CCC(=O)Nc1cccc(NC(=O)Cc2ccccc2C)c1 +N#Cc1ccc(C2NC(=O)c3ccccc3N2CC(N)=O)cc1 +CC1(O)CCN(C(=O)CCc2ccc(-c3ccccc3)cc2)CC1O +Nc1ncnc2c1ncn2C1OC(C(F)F)C(O)C1O +O=C1c2ccccc2S(=O)(=O)N1CCc1cccc(Cl)c1 +COCCNC(=O)Nc1cccc(COc2cccc(F)c2)c1 +Cc1nc(CNC(=O)Nc2ccc3c(c2)C(=O)CCC3)c(C)s1 +Cc1cc(=O)n2c3c(cc(S(=O)(=O)NC4CC4)cc13)CCC2 +Cc1cnn(CC(=O)Nc2ccn(Cc3ccccc3)n2)c1 +COC(=O)C=c1sc2n(c1=O)CN(Cc1ccccc1)CN=2 +Cc1ccc(CCNC(=O)Nc2ccc(CC(=O)NC3CC3)cc2)o1 +CCCC(C)C(=O)N(C)Cc1csc(C#CCO)c1 +Cn1cccc(C(=O)NCCCn2cccc2)c1=O +CN1CC2(CCN(C(=O)c3ccno3)CC2)OCC1=O +O=S(=O)(N1CCCC1)N1CCCCC1CCc1ccc(O)cc1 +CC1Cc2cc(S(N)(=O)=O)ccc2N1Cc1ccc(C#N)cc1F +CC(C)CCNC(=O)c1ccc(NC(=O)C(C)C)cc1 +C=CCN(CC=C)C(=O)Cc1cc(Cl)ccc1OC +O=C(Nc1cccnc1)c1ccc(NC(=O)c2cccnc2)cc1 +O=C(NCC1CC1)C1CCCN(C(=O)c2ccccn2)C1 +CC(=O)N(C)CC(=O)NC1(c2ccc(Br)cc2)CCC1 +Cc1ccc(CSc2ncc(CN3CCOCC3)c(=O)[nH]2)cc1 +NS(=O)(=O)c1ccc(NCc2cccc(Cl)c2)cc1 +COc1ccc(NC(=O)C2CCCN2C(=O)OCC(F)(F)F)cc1 +Cc1cc(=O)[nH]c(-c2ccc(NC(=O)c3ccc(C#N)cc3)cc2)n1 +CCOC(=O)c1ccc(NC(=O)c2cc3ccccn3n2)cc1 +Cc1cc(NCCc2c[nH]c3ccccc23)c2nncn2n1 +CC(NC(=O)c1[nH]ncc1Br)c1ccc(F)cc1F +O=C(c1ccoc1)N1CCCCC1CCc1cccs1 +Cc1ccc(N)c(C)c1S(=O)(=O)Nc1cccnc1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)cc2Cl)c1C +Cc1c(C(O)c2ccco2)cc2c(c1C)NC(=O)C2 +Cc1cc(NC(=O)CN2C(=O)c3ccccc3S2(=O)=O)on1 +CN(Cc1ccccc1)C(=O)CN1CCCc2ccccc21 +COc1ccc2ccn(CC(=O)N3CCC(C)CC3)c(=O)c2c1 +C#Cc1cc(F)c(NC(=O)NC(C)Cc2c(C)noc2C)c(F)c1 +CC(C)c1ccc(C(O)CNC(=O)c2cccnc2)cc1 +CCCc1nc(-c2ccc3c(c2)CC(C)N3S(C)(=O)=O)cs1 +CCOc1ccc2c(c1)CCNC2Cn1cnnn1 +Cc1ccc(C)c(SCC(=O)NC(C)C(N)=O)c1 +CCOC(CC)C(=O)Nc1ccc(F)c(C(=O)NC)c1 +CN(C(=O)c1ccc(Oc2cccnc2)cc1)c1cccc(C#N)c1 +CC(C)Oc1ccc(-c2nc3cc(O)ccc3o2)cc1N +NC(=O)C(NC(=O)CNC(=O)c1cccc(F)c1)c1ccccc1 +Cc1cccc(N2CC(c3nc4ccccc4n3C)CC2=O)c1C +Cc1nnnn1-c1cccc(NC(=O)Nc2cnn(CC(F)F)c2)c1 +O=C(CNC(=O)NC1CCCCC1)Nc1ccc(F)c(F)c1F +CNC(=O)Nc1cccc(NC(=O)c2cc(C(C)C)nn2C)c1 +CCOC(=O)c1sc2nc(C)nc(N3CCCC(CO)C3)c2c1C +COc1ccc(-c2nnc(N3CCOCC3)s2)c(N)c1 +COCCN1CCCC2(CCN(C(=O)c3ccc(=O)n(C)c3)C2)C1=O +CCC(CC)C(=O)Nc1ccc(C(=O)NCc2cccnc2)cc1 +CNC(=O)C1(NC(=O)c2cnn3cc(CCO)cnc23)CCCCC1 +O=C(Cc1ccccc1)NCC(=O)N1CCOC(c2ccccc2)C1 +Cn1c(=O)n(C)c2cc(NCCN3CCOCC3)ccc21 +CNC(=O)NCC(=O)Nc1ccc2nc(C3CCCO3)[nH]c2c1 +CN(C(=O)Cn1cc(C(F)(F)F)ccc1=O)c1ccccc1 +CN(Cc1cnn(C)c1)Cc1nc(Cc2ccccc2Cl)no1 +COc1cccc(CCc2nc(CCO)cs2)c1 +CN(c1ccc(C(=O)N2CCCC2)cc1)S(C)(=O)=O +COc1cc(C(=O)NC(C)C)ccc1OCc1cscn1 +COc1ccc(-c2cnnn2-c2cccc(N)c2)cc1OC +COc1ccc(CNC(=O)c2cccc(N(C)C)c2)cc1OC +CC(C)N1CC(C(=O)Nc2cccc(OCC(F)(F)F)c2)CC1=O +CCOc1ccc(C(=O)Nc2nnc(Cc3ccc(F)cc3)o2)cc1 +OCCOc1ccccc1OCc1ccn(-c2ccc(F)cc2)n1 +CN(CCO)C(=O)c1cc(COc2cccc(F)c2)[nH]n1 +COc1cccc(NC(=O)C(C)Oc2ccccc2N)c1 +CC(C)Cc1cc(C(=O)N2CCn3c(C(N)=O)cnc3C2)on1 +COCCN(Cc1ccco1)C(=O)NC(C)c1ccc(C)o1 +CNS(=O)(=O)c1ccc(C)c(C(=O)NC(C)C)c1 +CC1(C(=O)Nc2ccc(-n3cccn3)cc2)Cc2ccccc2C(=O)O1 +CN(Cc1noc(C2CCC2)n1)c1ncnc2cccc(F)c12 +CCCn1c(C)nnc1SCC(=O)N(C(C)C)C1CCCC1 +CC(=O)NC(C)(C)c1noc(Cc2ccc(CC(C)C)cc2)n1 +CCNC(=O)CCOc1ccc(C)cc1Br +CCOCc1ccc(NC(=O)NCc2nncn2C2CC2)cc1 +O=C(c1ccc(-c2ccco2)[nH]c1=O)N(Cc1ccsc1)C1CC1 +O=C(c1ccc(Cl)cc1)N1CCC(Nc2cccnc2)CC1 +Nc1ccc(Cn2c(=O)[nH]c3cccc(F)c32)cn1 +COc1ccc(S(=O)(=O)Nc2cccc(C)n2)cc1OC +Cc1cnc2n(c1=O)CC(C(=O)NCC(F)(F)F)CS2 +O=C(NCCCn1cccn1)c1ccc(N2CCOCC2)nc1 +Cc1ccc(-n2nnnc2CNC(=O)c2ccc3c(c2)OCO3)cc1 +CCCOc1ccc(F)cc1C(=O)c1cccc(N)c1 +c1cncc(N2CCCn3nnc(CN4CCOCC4)c3C2)c1 +COc1cc(C)c(C(=O)N(C)C(C)c2ccccc2OC)cc1OC +CC(C)(C)c1cnc(SCN2CCCCC2=O)o1 +CC(C)n1nnc(-c2ccc(C(=O)NCc3cccnc3)cc2)n1 +COc1ccccc1N1CCN(C(=O)c2ccc(C)n2C)CC1 +CS(=O)(=O)c1ccc(-c2noc(-c3cscn3)n2)cc1 +CCN(CC)S(=O)(=O)c1ccc(Cl)c(NC(C)=O)c1 +O=C(Nc1nc(C2CC2)cs1)c1cnn(-c2ccccc2)c1 +CC(Sc1nnnn1-c1ccccc1)C(=O)N(C)CCC#N +NC(=O)NCCCCC(=O)NC1CCCCC1C(F)(F)F +CCCc1ccccc1NC(=O)Nc1cnn(CC2CCCO2)c1 +Cc1cnn(CCC(=O)Nc2cc(S(C)(=O)=O)ccc2F)c1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)N(C)C3CCCCC3)ccc21 +Cc1ccc(C(=O)N2CCN(S(C)(=O)=O)CC2)s1 +CC(=O)c1cccc(NC(=O)Cc2ccc(C)cc2)c1 +Cc1ccc(C)c(OC(=O)Cc2ccc(-n3cnnn3)cc2)c1 +CC(C)CCN(C)C(=O)CCNC1=NS(=O)(=O)c2ccccc21 +COc1ccc(SC(C(N)=O)c2ccc(F)cc2)cc1 +CC(CNC(=O)c1ccsc1)COCc1ccccc1 +CCCc1ccc(NC(=O)Cn2ccccc2=O)cc1 +CN(C(=O)C1CC1)c1ccccc1C(=O)C(C#N)c1ccccn1 +COc1ccc(C(=O)Nc2cc(Cl)c(N)c(Cl)c2)cc1OC +COc1cccc(NC(=O)N2CCC(=O)NCC2C)c1Cl +CC(=O)N1CCC(NC(=O)CNc2ccc(C)cc2F)CC1 +CCOC(=O)C(C)(C)n1cc(NC(=O)N2CC(C)CCC2C)cn1 +COCc1nnc(-n2nnc(S(=O)(=O)C(C)C)c2N)s1 +Cc1ccccc1NC(=O)c1ccnc(OC2CCC2)c1 +CCCC(=O)Nc1ccc2c(c1)N(S(=O)(=O)CCC)CCC2 +O=C(NCc1cccc(C(F)(F)F)c1)c1cn2c(n1)COCC2 +Cc1nc2ncnn2c(O)c1CCC(=O)NCC(C)c1ccccc1 +CNc1snc(C)c1C(=O)NCCCn1cnc2ccccc21 +CC(NC(=O)c1ccoc1)C(=O)N(CC1CC1)C(C)c1ccccc1 +Cc1cccc(NC(=O)COC(=O)Cc2noc3ccccc23)c1 +COc1ccc(C(=O)N2CCN(Cc3occc3C)CC2)c(OC)c1 +C=CCN(C(=O)c1cnc2[nH]nc(C)c2c1)C1CCCC1 +CCc1nc(COc2cc(C)cc(C)c2)sc1CO +COc1cc(F)ccc1-c1ccc(=O)n(CC(=O)OC(C)C)n1 +COc1ccc(F)c(NC(=O)Cc2c(C)nn(C(F)F)c2C)c1 +Cc1cccc(N2CCN(C(=O)C3CCC3)C(C)C2=O)c1 +CCCNC(=O)CN(C)C(=O)c1ccc(Cl)c(N)c1 +CC(C)Oc1ccc(CNC(=O)CCc2ccsc2)cn1 +COCCN(Cc1ccc(C#N)cc1)Cc1ccccc1F +O=C(Nc1cc(F)ccc1F)c1cc(=O)c2ccccc2o1 +CC(C)Cn1ncc(C(=O)NCC(=O)c2cccs2)c1C1CC1 +Cc1c(Cl)cccc1NS(=O)(=O)c1ccc2c(c1)CC(=O)N2 +CCc1ccc(NC(=O)N2CCOCC2CC(C)O)cc1F +Cc1c(NCc2nnc(C(C)(C)C)o2)cccc1OCC(F)(F)F +COc1ccccc1-c1nc2c(F)cccn2c1CO +CSc1nn(-c2ccc(Cl)cc2)c(N)c1C#N +CCC(CC)NC(=O)C1CN(CC(N)=O)c2ccccc2O1 +CSc1ccc(NC(=O)COc2ccc(Cl)cc2)nn1 +N#CCCN(Cc1cnc2ncccn12)CC1CC1 +CC(=O)c1ccc(NC(=O)c2ccc(NC(=O)C3CC3)cc2)cc1 +COc1ccccc1-n1cnnc1SCc1ccc(F)cc1C#N +CC(c1cn(-c2ccccc2)nn1)N(C)CC(F)F +CC1CCN(c2cc(NC(=O)c3ccc(F)cc3)ncn2)CC1 +CC(NC(=O)N1CCN(c2ccccc2O)CC1)c1nncn1C +O=C(Nc1ccc2c(c1)COC2)c1ccccc1C(=O)N1CCCC1 +CN(C)C(=O)c1cccc(C(=O)NCc2cn(-c3ccccc3)nn2)c1 +CC(=O)NCCNC(=O)NCC1(c2ccccc2C)CCOCC1 +Cc1ccccc1NC(=O)Cn1[nH]c(=O)c2ccccc2c1=O +CC1(C)Cc2cc(C(=O)C3CCCOC3)ccc2O1 +Cc1nnc(NC(=O)c2ccnc(OC3CCC3)c2)s1 +Cc1ccc(CN(C)C(=O)Nc2cccc(F)c2F)s1 +COCCn1nc(C(=O)Nc2ccsc2C(=O)OC)ccc1=O +CCOC(=O)CCN1CCc2cc(F)ccc2C1 +N#Cc1ccccc1Cn1c(-c2nonc2N)nc2ccccc21 +CC(C)(C)OC(=O)Nc1cc(N)c(F)c(F)c1F +CCOC(=O)Cn1c(=O)cc(C)n(-c2cccc(F)c2)c1=O +Cc1ccc(CCc2c(C#N)nnn2-c2nccs2)cc1 +Fc1ccccc1CCNCc1ncc(-c2cccnc2)s1 +COc1ccc(-c2csc3nc4cc(N)ccc4n23)cc1OC +CC(=O)Nc1cc(C(=O)N(C)C(C)c2cc(F)ccc2F)ccc1C +CN(C(=O)c1ccc2ccccc2n1)C1CCc2ccccc21 +CCN1CCN(C(=O)c2cc3c(s2)-c2ccccc2OC3)CC1 +Cn1c(=O)[nH]c2cc(C(=O)Oc3cccc(-c4nnco4)c3)ccc21 +CC1CCCCC1OCCNC(=O)c1ccc(N(C)C)nc1 +CSc1ccc(S(=O)(=O)N2CCCCCC2)cc1 +CCN(CC)C(=O)c1csc(COc2ccc(Cl)cc2)n1 +CCOC(=O)CC(C)CNC(=O)c1c(C)nn2c(C)cc(C)nc12 +COc1cc(OC)cc(C(=O)OCC(=O)Nc2ccccc2C#N)c1 +Cc1ccccc1CNC(=O)N(C)Cc1nccn1C(F)F +COC(=O)N(C)c1ccc(NC(=O)c2ccccc2O)cc1 +Cc1nc(N)ccc1NC(=O)c1ccc(Cl)cc1 +CCOc1ccc(CN(C)C(=O)c2ccc(NC(C)=O)s2)cc1 +CCC1C(=O)Nc2c(C)cc(C(O)c3cccc(C)c3)cc21 +COc1ccccc1CN(C)C(=O)CSc1ccc(C)cn1 +c1ccc(CN2CCOC3C(OCc4cccnc4)CCC32)nc1 +CN(C)S(=O)(=O)c1ccc(C(=O)Nc2onc3c2CCCC3)cc1 +O=C(CNc1ccn(-c2ncccc2Cl)n1)NCC1CC1 +Nc1ccc2nnc(C=Cc3ccc(Cl)cc3)n2c1 +Cn1cc(CNc2cnn(CC(F)(F)F)c2)c(-c2ccncc2)n1 +COCC(=O)NCc1cc(=O)oc2cc(C)c(Cl)c(C)c12 +Cn1cnnc1SCc1nc2ccccc2s1 +Cc1ccc(-n2nc(-c3nc(-c4ccncc4)no3)c3c2CCC3)cc1 +CN(C)c1cccc(OCC(=O)N2CCNCC2)c1 +CCC(CC)N(CCO)c1cccc(Cl)c1CO +Cc1ccccc1C1CN(Cc2c[nH]nc2-c2cccnc2)CCO1 +COc1ccc(C(=O)Nc2cc(F)ccc2C)cc1 +COc1ccccc1C(=O)NCC(=O)Nc1cccc(C(C)=O)c1 +Cc1n[nH]c(C(=O)N2CCN(C(C)C)CC2)c1Br +CC1(C)C2CCC(C2)C1(C)NC(=O)CN1CCOCC1 +CS(=O)(=O)N1CCOCC2(CCN(c3ncc(F)cn3)CC2)C1 +CCc1oc2ccccc2c1CN1CCC(N2CCOC(C)C2)CC1 +Cc1ccccc1Nc1nc(Cn2cc(Cl)c(=O)[nH]c2=O)cs1 +CN(CC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1)S(C)(=O)=O +CCn1cnnc1CNC(=O)NC(C)(CO)C1CCCCC1 +O=C(NCCOc1ccc(Cl)cn1)c1cccs1 +CC(C)c1nnc2n1CCN(C(=O)c1occc1-c1ccccc1)C2 +C#CCN1CCN(C2CCN(c3ccccc3Cl)C2=O)CC1 +CCOC(=O)c1sc2ncnc(NC(CC)CO)c2c1C +O=C(NCc1nnnn1-c1cccc(F)c1)Nc1cccc(Cl)c1 +CS(=O)(=O)N1CCc2ncnc(N3CCC(O)C3)c2CC1 +NC(=O)COc1ccc(CNC(=O)Nc2cccc(Cl)c2)cc1 +Cc1ccc(CNC(=O)NCCNC(=O)c2ccc(C)c(F)c2)cc1 +CC1(C)Cc2nc3sc4[nH]c(=O)[nH]c4c3cc2CO1 +CCOc1cc(CNc2cccc(C)n2)ccc1O +CCC1(C)CC(CC#N)(c2ccc(OC)cc2)CCO1 +COc1cc(C)c(C(C)C)cc1S(=O)(=O)n1ccnc1C(C)C +Cc1nc2cc3c(cc2n1Cc1cccc(C#N)c1)OCCO3 +COCCn1c(SCCC#N)nnc1-c1ccc(Cl)cc1 +COc1ccc(NC(=O)N2CCC(Cc3cnn(C)c3)C2)cc1C +Cc1nc2ccccc2nc1NCCC(=O)NC(C)C +O=C1NC2=C(C(=O)N(Cc3ccc(F)cc3)C2)C(c2ccccc2)N1 +COc1cc(C#N)ccc1OCCCC(=O)Nc1scnc1C +COc1cc(C)c(C(=O)CCc2nc(C)cs2)cc1C +CC(C(=O)NCC1CCCO1)N1CCOC(Cn2cccn2)C1 +CC1CCC(C(=O)N2CCC(OCc3ccccc3F)CC2)O1 +C=CCNC(=O)c1cccc(S(=O)(=O)Nc2cccc(C)c2)c1 +COc1ccc(NC(=O)CN(C)C(=O)c2cc(C)oc2C)cc1 +CN(CCOCC1CC1)C(=O)Nc1ccc2c(c1)oc(=O)n2C +N#Cc1ccc(Oc2nccc(C(F)(F)F)n2)cc1 +CCOCCCNC(=O)c1c(-c2ccccc2Cl)noc1C +OC(COc1ccccc1)Cn1c(C2CCCO2)nc2ccccc21 +Brc1ccc(CN2CCOCC2)nc1 +NC(=O)c1ccc(Cl)cc1NC(=O)C1CC2CCC1O2 +CC(C)Oc1cc(OC2CC2)cnc1C(=O)N(C)C +Cc1cc(C(=O)N2CC(C(=O)NCC(F)(F)F)C2)no1 +Cc1c(NCC(=O)N2CCCCC2)cccc1C(=O)N1CCOCC1 +Fc1ccc(-c2n[nH]cc2CNCCc2cccnc2)cc1 +COCCN1CC(C(=O)Nc2ccc(C)c(C)c2)CC1=O +CSc1ncccc1C(=O)Nc1ccc(-n2cnnn2)cc1 +Cc1cccc2[nH]cc(CC(=O)NCC(O)c3cccc(F)c3)c12 +CC(=O)NC(CC(=O)Nc1ccccc1C(C)(C)C)c1ccccc1 +COc1cc(C(=O)Nc2cccc(O)c2)ccc1OC(F)F +NC(=O)c1cc(NC(=O)c2cnccn2)cc(C(N)=O)c1 +CCOc1ccc(-c2nnn(CC(=O)N3CCCC(C)C3)n2)cc1 +Cc1cc(NC(=O)c2cccnc2OCC(F)F)nc(C(C)C)n1 +CC(=O)NCc1cccc(Cc2ccc(F)cc2)c1 +Brc1cnc(Nc2cnn(-c3ccccn3)c2)nc1 +CSc1c[nH]nc1NC(=O)c1ccc(C)c(F)c1 +Cc1ccc(-c2noc(-c3ccc(O)c(Cl)c3)n2)nn1 +Cc1noc(C(C)NC(=O)c2cccc(OCc3ccccc3)c2)n1 +CC(C)(C)CC(=O)NCc1nnnn1-c1ccc(Cl)cc1 +Cc1c(C(=O)N2CCN(c3ncccn3)CC2)cnn1-c1ccncc1 +CCc1ccc(CNC(=O)C(NC(C)=O)C(C)C)s1 +CCCC(C)NC(=O)CS(=O)(=O)c1ccccc1OC +Cc1nn(C)c2[nH]c(=O)c(CCC(=O)N(CC(C)C)C3CC3)c(C)c12 +OCc1nnn(-c2ccc(Cl)c(Cl)c2)c1CO +O=C(NCCc1ccncc1)NCc1ccc(Br)cc1 +Nc1nc(-c2ccccc2)cnc1C(=O)NCCO +COc1ccc(Cc2nc(-c3cccs3)no2)cc1OC +CC1c2ccsc2CCN1C(=O)c1csc2c1CCCC2 +Cc1cnc2c(C(=O)NCc3ccccc3-n3ccnc3)cnn2c1 +COc1ccccc1NC(C)C(=O)N1CCCCC1 +Cc1ccccc1CC1(CO)CCCN(C(=O)CN2CCCC2=O)C1 +O=C(NCc1cccc(F)c1)Nc1ccc(C(=O)NC2CC2)cc1 +Cc1[nH]n(-c2ccccc2)c(=O)c1C(=O)c1ccc(F)cc1 +O=C(NC1Cc2ccccc2C1)c1c[nH]nc1-c1ccccc1 +CC(Sc1nnc(N)[nH]1)C(=O)NC(C)c1ccccc1 +CNC(=O)c1cnc(C=Cc2cc(F)ccc2Br)s1 +COc1cccc(-c2c(C#N)nnn2-c2ccc(C)cc2)c1 +CCOC(=O)c1sc(NC(=O)CC)c(C#N)c1C +O=C(Cc1noc2ccccc12)N1CCC(Cn2cccn2)CC1 +CCc1cc(-c2c(C#N)c(N)nc3c2COCC3)[nH]n1 +CC(=O)c1ccc(O)c(NC(=O)c2occc2C)c1 +CCS(=O)(=O)NCc1nnc(C(=O)Nc2ccccc2)s1 +O=C(NCc1cccnc1)C1(c2ccccc2)CC1 +CC(Oc1ccc(C#N)cc1)C(=O)N=c1[nH]ccn1Cc1ccccc1 +CSc1ccc(Cl)cc1NC(=O)NCc1ccco1 +Cc1ccc(C)c(C(=O)Nc2cc(N)ccc2F)c1 +C#CCOCC1CCCN(C(=O)c2cc(-c3cccs3)n[nH]2)C1 +CC(C)(C)OC(=O)N1CCC(n2cccc2)CC1 +Cn1c(SCc2nc(C(C)(C)C)no2)nnc1N1CCOCC1 +CC(C)Cc1cc(-c2nn3c(-c4cccnc4)nnc3s2)n(C)n1 +Cc1cccc(NC(=O)N2CCN(Cc3cc(C)no3)CC2)c1 +Cc1cc(Br)cc2cc(C(N)=O)c(=O)oc12 +Cc1ccccc1OCCOC(=O)c1ccc(S(C)(=O)=O)cc1 +Cc1cccc(CC(=O)Nc2cnn(-c3ccccc3F)c2)c1 +Cc1cc(NC(=O)C2CC(=O)N(c3ccccc3Cl)C2)ccn1 +CCOC1CCCN(c2ncc(Br)cc2N)C1 +CC(=O)N1CCN(C(=O)CSc2nc(=O)ccn2C(C)C)CC1 +CCCc1cc(=O)[nH]c(SCC(=O)Nc2ccc3c(c2)OCO3)n1 +O=C(CCOC1CCOCC1)NC1CC(c2ccccc2)C1 +COCCCC1CCCCN1C(=O)c1ccc(S(N)(=O)=O)cc1 +CC(OCC(F)(F)F)C(=O)Nc1ccccc1N +O=S(=O)(Cc1ccc(F)cc1)NCc1ccc(F)cc1 +COc1ccc2nnc(C(=O)NCCCN3CCOCC3)nc2c1 +Cc1cccc(NC(=O)c2nc3nccc(C)n3n2)c1 +O=C(NCc1cn(-c2ccccc2)nn1)c1cccc(-n2cccn2)n1 +C#CCNc1cccc(C(=O)N2CCOCC2)c1C +CN(C(=O)c1ncn(-c2ccccc2)n1)C1CCCc2c1cnn2C +CCCNc1ncnc(Nc2ncc(C(F)(F)F)cc2Cl)c1N +Cc1cccc(C(=O)N2CCn3cc(CNS(C)(=O)=O)nc3C2)n1 +Cc1ccc(OC(=O)Cn2cnc3c(oc4ccccc43)c2=O)cc1C +COCc1ccc(C(=O)N2CCCC2CC(=O)c2ccccc2)cc1 +CCN(C)S(=O)(=O)N1CCN(Cc2nccn2C(F)F)CC1 +COc1cc2nc(-c3ccccc3N(C)C)nc(N)c2cc1OC +Cn1nccc1-c1nnc(NC(=O)c2c(F)cccc2Cl)o1 +Cc1ccc(CC(=O)Nc2ccc3oc(C)nc3c2)cn1 +O=C(CCn1ccnc1)NC1CC1c1cccc(C(F)(F)F)c1 +CCOC(=O)C1(NS(=O)(=O)c2cc(C)sc2C)CCCC1 +O=C(CN1CCOCC1)Nc1cccc(C(=O)NC2CCCCC2)c1 +Cn1c(C(=O)NC2CCCc3ccccc32)cc2c(F)cccc21 +Nc1cc(S(=O)(=O)NCC2CCCCO2)ccc1F +COCc1cccc(C(=O)C(C#N)c2nnc3n2CCCCC3)c1 +Cc1cc(C(=O)Nc2ccnn2C2CCCCC2)c(C)o1 +Cn1nccc1NC(=O)c1c(Cl)ccc(Cl)c1Cl +CC(=O)c1ccc(NC(=O)COC(=O)c2cccc(Cl)c2N)cc1 +Cc1onc(-c2cccc(F)c2)c1C(=O)NCc1ccccc1 +Cc1[nH]ncc1C(=O)NC(C)c1cc(F)ccc1N1CCOCC1 +Cn1cc(-c2nn3c(-c4cc(F)ccc4F)nnc3s2)cn1 +CCOC(=O)c1ncn2cc(Br)ccc12 +CCOc1cc(CNC(=O)Nc2cc(OC)ccc2F)ccc1OC +CSc1ccc(C)c(C(=O)N2CCCCC2CC(N)=O)c1 +CNC(=O)c1ccc(NC(=O)c2cccc(C(=O)N(C)C)c2)cc1 +CCn1c(SC(C)C)nnc1-c1cccs1 +Cc1nc(C)c(C(=O)OCc2csc(-c3cccs3)n2)s1 +Cc1onc(-c2ccccc2Cl)c1C(=O)Nc1nccs1 +O=c1[nH]c(CCn2nccn2)nc2c(Cl)cc(Cl)cc12 +O=C(c1cscn1)N1CCCc2c(Cl)ccc(F)c21 +O=C(c1ccc2ccccc2n1)N1CCC(O)(C(F)(F)F)C1 +CSc1ccc(C)c(C(=O)OC(C)c2nc(C)no2)c1 +COc1nc2c(cc1C(=O)N(C)Cc1noc3c1CCCC3)CCC2 +COCCNC(=O)CSc1nnc2c(n1)[nH]c1ccc(F)cc12 +c1cc(NCc2cccs2)cc(-n2cnnn2)c1 +O=C(CO)N1CCN(c2cccc(Cl)c2)CC1 +CCN(CC)C(=O)c1cc(-c2cccs2)on1 +Cc1ccc(C)c(NC(=O)C2CN(Cc3ccccc3)CCO2)c1 +CN(Cc1ccc2c(c1)OCO2)c1c(C#N)c(=O)n(C)c(=O)n1C +NC(=O)c1ccc(OCC(=O)N2CC=C(c3ccccc3)CC2)cc1 +CCC(CC)NC(=O)C(C)Sc1nnc(C(C)(C)C)o1 +COC(=O)CCn1c(CO)nc2cccc(F)c21 +CCCn1ncc(C(=O)NCc2ccc(C(F)(F)F)cc2F)c1C +O=C(Cc1ccc(Cl)cc1F)NCc1ccncc1 +CCN(CC)S(=O)(=O)c1cc(NC(=O)Cc2ccc[nH]2)ccc1C +Cc1ccc(CNC(=O)N(C)CC2CCCC2)cn1 +CCSc1nnc(C(C)NC(=O)Cc2ccsc2)n1C +O=C(Cn1cccn1)N(CCO)C1CCCCC1 +Cc1cc(Cl)ccc1NC(=O)c1ccc2c(c1)OCC(=O)N2 +COc1ccc(C(O)CNC(=O)CCc2ccncc2)cc1 +Cc1ccsc1CN(C)C(=O)c1ccccc1O +CC(NC(N)=O)C(=O)N1CC=C(c2ccccc2Cl)CC1 +O=C(CCCc1cccs1)NCc1nc2ccccc2s1 +CC(C)COC(=O)N1CCN(Cc2cncs2)CC1 +Cc1cc(C)n(-c2ccc(N3CC(C)OC(c4ccccc4)C3)nn2)n1 +CC(=O)NCc1noc2c1CN(Cc1cccs1)CC2 +O=C(CSc1cn[nH]n1)Nc1ccc(OC(F)(F)F)cc1 +Cc1ccc(C(=O)CCC(=O)N2CCC(=O)CC2)cc1C +N#CCCn1c(CNC(=O)c2ccccc2)nc2ccccc21 +COc1ccc(F)cc1COc1c(OC)cccc1C(N)=O +O=C1NCCCCC1Oc1ccc(F)cc1Br +Nc1cc(C(O)CCN2CCOCC2)ccc1Cl +CC1CCCC(CNC(=O)N(C)Cc2nccn2C(F)F)C1 +COC(=O)C(Sc1nnnn1C1CC1)c1ccccc1C +CCCCNC(=O)c1sc(NC(C)=O)c(C(=O)OC)c1C +CCCC(=O)NC(C(=O)OC)c1ccc(Br)cc1 +O=S(=O)(N=c1[nH]c(C2CC2)cs1)c1cccc2cnccc12 +Cc1ccc(-c2nc(C(=O)N(C)Cc3cnn(C)c3)cs2)c(C)c1 +Cc1noc(C)c1CC(=O)NCc1ccnc(-n2ccnc2C)c1 +Cn1nc(C(=O)NCC(=O)c2ccccc2)c2ccccc2c1=O +CCN(Cc1cccc(C)c1)C(=O)NCc1cccnc1OC +COc1ccc(CCc2ccc(OC)c(O)c2)cc1O +COC(=O)NCC(=O)N(C)CCc1ccc(F)cc1 +CCS(=O)(=O)Nc1ccc(C#CCCO)cc1F +CCOC(=O)N1CCN(CC(O)c2ccc(C)cc2)CC1 +Cc1nc(C)n(CC2CN(Cc3nc(C4CC4)no3)CCO2)n1 +Cn1nnc(C#N)c1-c1ccccc1Br +CC(C)C(NC1=NS(=O)(=O)c2ccccc21)C(=O)N(C)CCC#N +Cc1nnc(SCCCc2cnn(C)c2)n1N +CCOC(=O)c1nn(-c2ccccc2)c(=O)cc1Cl +CCc1ccccc1-n1nnc(C#N)c1C(F)(F)F +CNC(=O)c1cccc(OC(=O)Cc2coc3cc(C)c(C)cc23)c1 +CCN(CC)C(=O)CN(C)c1nc(-c2cccnc2)nc2ccccc12 +CCCNC(=O)c1cc2n(n1)CCN(Cc1ccccc1)C2=O +COC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +CCc1nnsc1C(=O)N1CCC(N2CCNC2=O)CC1 +O=C(NCCn1nc(-n2cccn2)ccc1=O)c1ccc(Cl)cc1 +NC(=O)c1sc2nncc(-c3ccc(Cl)cc3)c2c1N +Cn1ccc(NC(=O)Cn2nc(-c3ccccc3)ccc2=O)n1 +CC1c2cccn2CCN1C(=O)Nc1ccc(F)cc1 +O=C(NCc1ccnc(OC2CCC2)c1)c1ccc2c(c1)OCCO2 +O=C(NCc1ccc2c(c1)OCCO2)c1ccsc1 +Cc1ccc2nc(CNc3ccc4oc(C)nc4c3)cc(=O)n2c1 +COCC(C)OC(=O)C(C)c1ccc2c(c1)OCCO2 +O=C(Nc1cnc(N2CCCCC2)nc1)c1cccc(F)c1 +Cc1nc(-c2nn3c(-c4cccc(Cl)c4F)nnc3s2)co1 +Cc1ccc2ncc(CN3CCOC4CCCCC43)n2c1 +CCc1nc(CNc2ccccc2NC(=O)CC2C=CCC2)cs1 +Cc1cccc(NC(=O)c2cnn(-c3ccc(F)cc3)c2C(C)C)n1 +CC(Sc1ncnc2ccccc12)C(=O)N(C)Cc1ccccc1 +CCOc1ccc(C(=O)Nc2ccccc2OC(F)(F)F)nn1 +COc1ccc(CC(=O)Nc2sccc2C#N)cc1OC +COc1ccc(C(=O)Nc2ccc(Oc3ccc(C#N)cc3)cc2)nn1 +Cc1cccc(CS(=O)(=O)NCC(C)(O)c2cccs2)c1 +O=S(=O)(CCN1CCCSc2ccccc21)c1ccccc1 +CCC(=O)N1CCc2cc(C(=O)N(C)c3nc(C)cs3)ccc21 +COC(=O)C1CCN(C(=O)c2cccc3ccccc23)CC1 +COCCC(C)NC(=O)c1ccc2c(c1)OCCO2 +O=C(CSc1nnc2ccccn12)Nc1cc(F)ccc1F +O=C(NCC1CCCCC1)c1ccc(Cn2ccnc2)cc1 +Cc1cc(C)cc(NC(=O)C2CN(S(=O)(=O)C3CC3)C2)c1 +CC1CN(CCNC(=O)Nc2ccccn2)CC(C)O1 +C=CCNC(=O)Cn1cnc2c(F)cc(Br)cc2c1=O +COC(=O)c1ccc(OCc2ccc(C#N)cc2)c(OC)c1 +CCC(C)Nc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1 +Cc1nc(-c2ccc(NC(=O)C3OCCc4ccccc43)cc2)oc1C +CC(=O)NC(CC(=O)OC(C)c1cc(F)ccc1F)c1ccccc1 +NC(=O)c1cc(NCC(=O)N2CCc3ccccc3C2)ccc1F +N#Cc1ccc(N2CCC(c3nc(-c4ccccn4)no3)CC2)nc1 +Cc1ccc(CN(C)C(=O)Cc2ccc(N3CCCC3=O)cc2)s1 +CC(=O)N1CCN(C(=O)Nc2sc(C)c(C)c2C#N)CC1 +CC(C)(CO)NS(=O)(=O)c1cc(Cl)ccc1Cl +CCCC1CN(C(=O)COc2ccc3c(c2)CCC(=O)N3)CCO1 +CN(Cc1nnc(-c2ccccc2)o1)C(=O)c1ccc(F)cc1 +COc1ccc(CCNC(=O)Cc2cnn(-c3ccccc3)c2)cc1 +O=C(NC1CC1)c1nc2ccc(C(F)(F)F)cc2s1 +Cc1ccc2ncc(C(=O)Nc3ccc4oc(=O)[nH]c4c3)n2c1 +Cc1cc(NC(=O)CCn2nc(C)c3ccccc32)n(C)n1 +O=C(NCCN1CCN(C(=O)C2CCC2)CC1)N1CC2CCCC2C1 +CCCc1oncc1C(=O)N1CC(c2cccnc2)C1 +Cc1cccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c1O +Cc1noc(CCC(=O)N2CCC(C)c3ccccc32)n1 +CCNC(=O)NC1(C(=O)N(CC)CC2CC2)CCCC1 +COc1ccc(NC(=O)c2ccc(N)cc2Cl)cn1 +O=C(Cn1nc2c3ccccc3ncn2c1=O)NC1CCCC1 +O=C1OCCN1CCc1nc(-c2ccc3c(c2)OCCO3)cs1 +CC(=O)Nc1cccc(C(=O)Nc2ccccc2N2CCOCC2)c1 +CCCCNC(=O)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1 +Cc1ccc(NC(=O)CNc2ccc(F)c(C(N)=O)c2)c(Cl)c1 +O=C(Nc1c(F)cccc1NC1CC1)C1CC=CC1 +O=C(COC(=O)c1cccc2ncccc12)Nc1cc(F)ccc1F +COc1ccccc1-n1ccnc1SCC(=O)NC(C)(C)C +Cc1cc(CN(C)C(=O)NC2CCN(CC(F)(F)F)C2)no1 +Cn1cc(C(O)CNC(=O)Nc2cc(F)cc(N3CCCC3)c2)cn1 +Cc1nnnn1-c1cccc(NC(=O)NC2CCCCC2C)c1 +O=c1c2c3n(nnc-2nn1-c1ccccc1)CCC3 +CSc1nnc(NC(=O)CSc2nccn2C)s1 +CC(=O)NC(C)c1nc2ccccc2n1Cc1cc(C)ccc1C +CCCNC(=O)CCNC(=O)NCc1cccs1 +Cc1sc2nc(CN(C)C(C)c3cccs3)nc(N)c2c1C +Cc1c(C(=O)NC(C)CO)cnn1Cc1ccccc1 +CC(=O)c1ccccc1NC(=O)C1CCN(C(=O)N(C)C)CC1 +Cc1cccc(C2CC2C(C)NC(=O)c2ccnc(-n3cncn3)c2)c1 +COc1ccc(CC(=O)c2ccc(OC)cc2O)cc1 +COc1ccc(Nc2cc(C)nc(C)n2)c(OC)c1 +CC(C1CC1)N(Cc1ccccc1)C(=O)CN1CCOC(C)(C)C1 +Cc1cc(C)n2nc(CC(=O)NCC3CCCO3)nc2n1 +CC(C)OCCCNS(=O)(=O)c1ccc2c(c1)CCN2 +N#Cc1ccc(NCCCNC(=O)c2cccc(O)c2)c(F)c1 +Cc1cc(NC(=O)CN(C)S(=O)(=O)Cc2cccc(C#N)c2)no1 +C#Cc1cccc(NCc2cc(=O)n3ccccc3n2)c1 +CC(=O)Nc1cccc(C(=O)OCC(=O)N2CCOCC2)c1 +Cc1cc(C)n2nc(S(=O)(=O)Nc3cccc(F)c3)nc2n1 +O=C(Nc1ccc2nc(-c3ccco3)[nH]c2c1)c1ccc2[nH]cnc2c1 +Nc1cc(NC(=O)CCCOCC2CCCO2)ccc1F +NC(=O)c1cccnc1Nc1cccc(Br)c1 +COc1ccc(NC(=O)COCc2nc(C)no2)cc1C +CCOc1ncccc1C(=O)NC(C)Cc1ccccc1F +Cc1ccc(F)cc1C(=O)NCCC(=O)NC1CCCC1 +CCC(NC(=O)c1csc(NC(C)=O)n1)C(C)C +Cc1nn(C)c2ncc(NC(C)c3ccccn3)cc12 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)N(CC1CCOC1)C1CC1 +COc1ccc2cccc(CC(=O)NCc3n[nH]c(=O)[nH]3)c2c1 +CC(C)C(=O)Nc1nc(-c2ccc3c(c2)OCO3)cs1 +CCOC(=O)CC(C)CNC(=O)c1cccc(Cl)c1Cl +Cc1ccc(S(=O)(=O)N2CCC(C)CC2)c(C)c1 +O=C1CNc2[nH]c3ccc(Br)cc3c21 +O=C(NC1CCCC1)C1CCCN1C(=O)C12CC3CC(CC(C3)C1)C2 +COc1ccc(NC(=O)C2CCC(Cn3cnnn3)CC2)c(OC)c1 +N#Cc1ccc(C2Nc3ccccc3C(=O)N2Cc2ccccc2)cc1 +CCOC(=O)c1nnsc1NC(=O)CCc1ccc(C#N)cc1 +CN(Cc1nnc(C2CC2)n1C)C(=O)Cc1ccc(F)cc1F +CC(C)n1c(CCCO)nc2cc(Cl)ccc21 +CCC(C(=O)N1CCC(C(=O)OC)CC1)c1ccccc1 +O=S(=O)(c1cccc(C(F)(F)F)c1)N1CCC(O)CC1 +CN(Cc1cnn(C)c1)C(=O)NC(c1ccccc1)c1ccccc1 +Nc1cccnc1Sc1ccc(C(F)(F)F)cn1 +CC(C)(C)OC(=O)Cn1nnc(-c2ccc(C(N)=O)cc2)n1 +NC(=O)C1CCCN1C(=O)CC(c1ccccc1)c1ccccc1 +CN(CCc1ccc(F)cc1)C(=O)C1CCCN1C(=O)C1CC1 +CC1CCCCC1NC(=O)C1CCCN1C(=O)OC(C)(C)C +Cc1cc(NC(=O)CNc2ccc(C)c(F)c2)n(C(C)(C)C)n1 +O=c1ccc(-c2noc(-c3n[nH]c4ccccc34)n2)c[nH]1 +Cn1ccnc1SCC(=O)Nc1ccc(N)cc1Br +Cc1ccc2c(c1)c1cccc3c1n2CCN3CCC#N +CCOC1CCN(C(=O)c2nc(-c3ccc(Cl)cc3)oc2C)CC1 +COc1cc(CN(C)S(C)(=O)=O)ccc1SC +CCN(CC(C)(C)O)C(=O)c1cc(N2CCCC2=O)ccc1Cl +COc1ccc(N)cc1CNc1ccc(C#N)cc1F +CCC(=O)NCc1ccccc1-c1cccc(-n2cccn2)c1 +O=C(Nc1nc2ccccc2n1Cc1ccccc1)C1CCCO1 +COC(=O)c1ccc(Cn2ccc(=O)c3cc(F)cc(F)c32)o1 +O=C(NCc1cccc(Cl)c1)c1ccc2[nH]ccc2n1 +Cc1cc(Nc2ncnc(Nc3cc(F)ccc3F)c2N)no1 +CC(=O)NCCNC(=O)CCc1ccc(Cl)cc1 +Cc1ccc(CN(CCCO)Cc2cccc3cnccc23)s1 +COc1ccc(Cc2nnc(C(=O)NCC3CCCO3)o2)cc1OC +O=C1N(CCCO)c2cc3c(cc2NC12CCCC2)CCCC3 +Cc1cnc(C(=O)Nc2ccc(F)cc2F)c2cccc(N)c12 +Cc1oc(C2CCC2)nc1C(=O)NCCc1nc2ccccc2n1C +Cc1cc(C(=O)Nc2ccc(Cl)cc2F)no1 +COc1ccc(-c2n[nH]cc2C(=O)Nc2cn(C)c(=O)cc2C)cc1 +CC(=O)c1ccc(CNC(=O)c2ccnc(-n3ccnc3)c2)nc1C +CCn1c(CNc2cc(C(N)=O)ccn2)nc2ccccc21 +CCCNC(=O)c1cccc(NC(=O)COc2cccc(C)c2)c1 +COc1ccc2nc(N3CC(C(N)=O)C3)sc2c1 +COC(=O)C1CCN(c2cccc3ccncc23)CC1 +CC(C)CC(NC(N)=O)C(=O)Nc1ccc(F)c(C#N)c1 +Cc1cc(C(=O)Nc2ccnn2C(C)C)c(C)n1C1CCCCC1 +COC(=O)CCC(=O)N1CCN(c2ccc(F)cc2)CC1 +COc1cccc(OC)c1C(N)C(=O)NCCO +CCn1nc(C)c(CNc2cc(OC)c(Cl)cc2OC)c1C +OC(CNc1ncccn1)(c1ccccc1)c1ccccc1 +Cc1ccc2nc(CN(C)C(=O)c3cc(C)nc(C)n3)[nH]c2c1 +CC(C)OC(=O)C(C)N1C(=O)C(C)Oc2cccc(N)c21 +CCNc1nc(N2CCCCC2)nc2c1C(=O)CCC2 +Cc1cc(NC(=O)Cc2cccc(OC(C)C)c2)[nH]n1 +CCOCCCNC(=O)c1c(C)noc1-c1ccc(C)cc1 +O=C(Cc1ccc(Cl)cc1)NCc1nccc(N2CCCCC2)n1 +Cc1nn(C)c2ncc(NC(=O)Cc3ccc(O)cc3)cc12 +CCOC(=O)Nc1ccc(C(=O)NCc2nc(C)cs2)cc1 +N#Cc1cccc(C(=O)NCc2ccc(Cl)cc2)c1 +CC(=O)Nc1ccc(Cl)c(C(=O)N(C)Cc2cc(C3CC3)[nH]n2)c1 +CC(C)c1nc(CC(=O)NC2CCN(S(C)(=O)=O)CC2)cs1 +Cc1noc(C)c1CSc1ccccc1C(=O)NCC(C)O +COC(=O)C1NCC(C)c2ccc(Br)cc21 +CN(C(=O)CNC(C)(C)c1ccc2c(c1)OCO2)C(C)(C)C#N +Cc1csc(C2CN(Cc3nc(-c4ccco4)no3)CCO2)n1 +CCOc1ncccc1C(=O)Nc1cccc(Cl)c1F +CC(C)n1cnnc1SCCCOc1ccccc1 +O=C(c1ccc(N2CCOCC2)c(F)c1)N1CCN(CCO)CC1 +COc1ccc(NC(=O)NC(C)c2ccc3c(c2)OCO3)cc1 +Cc1cc(C)nc(SCC(=O)Nc2ccnn2CC(C)C)n1 +CC(CN1CCCC1=O)NC(=O)NCCc1cccs1 +CCC(NC(=O)N1CCCC(COC)C1)c1cc(F)ccc1F +Cc1c(C(=O)NCC2CC2C)sc2ncn(C)c(=O)c12 +CC(NC(=O)c1ccc2c(c1)OCCO2)c1ccccc1Cl +CC(C)C(=O)Nc1ccn(CCc2ccccn2)n1 +CSc1nc2nc(C)c3c(=O)n(C(C)C)ccc3n2n1 +Cc1ccc(CN(C)Cc2cc(=O)n3nccc3[nH]2)s1 +CCNC(=O)C1(NC(=O)Cc2c(C)nn(C)c2C)CCCCC1 +Cc1cc(CN(C)C(=O)NCc2cccs2)no1 +CCCCS(=O)(=O)NCC1CCN(C(=O)OC)CC1 +COc1nc(NC(C)=O)nc(C)c1Br +COc1ccc(CNC2C(c3cncnc3)CC(O)C2O)cc1 +CN(Cc1ccccc1)C(=O)c1ccc2ncnc(N3CCCC3)c2c1 +COCCN(CC(=O)N(C)C)C(=O)C1CC2CCC1O2 +CCCN(CC1CCCCO1)C(=O)c1cc2c([nH]c1=O)CCCC2 +CC(=O)Nc1ccc(CCNCc2cn(C)nc2-c2cccnc2)cc1 +Cc1cc(C)cc(OCC(=O)Nc2ccc(C#N)cc2)c1 +Oc1ccc(C2Nn3c(Cc4ccccc4)nnc3S2)cc1 +O=C(NCc1ccc(Cl)c(Cl)c1)c1ccc2[nH]ccc2n1 +Cc1cc(C(=O)NCC2(c3ccccc3)CCOCC2)oc1C +COc1cc(Cl)c(C)cc1NCc1ccc(S(C)=O)cc1 +CCn1ccc(NC(=O)C2CCC(=O)N(C)C2c2ccccc2F)n1 +O=C(Nc1ccc(F)cc1F)N1CC2CCC(C1)N(CC1CC1)C2=O +Cc1cc(Br)ccc1NC(=O)c1cccnc1N(C)C +NC(=O)NCCCCC(=O)N1CCN(c2ccccc2F)CC1 +Cc1cccc(C)c1NC(=O)CNC(=O)c1ccccn1 +CCC(NC(=O)c1c[nH]nc1C1CCCCC1)C(=O)OC +Cc1ccc(C(=O)NCC(=O)NCCCc2ccccc2)s1 +Cc1nc(C)c(C(C)Nc2nc3ccccc3[nH]2)s1 +CCOC(=O)N(C)CC(=O)Nc1nc(C)cs1 +COc1ccc(F)c(NC(=O)Cn2ncc3ccccc32)c1 +CCOc1ccccc1C1C(C(N)=O)C(C)=Nc2ncnn21 +CCC(C)(C)c1ccc(OCCNC(=O)CC#N)cc1 +COc1ccc(NC(=O)N2CCN(C)c3ncccc32)cc1OC +CNC(=O)CC(c1ccccc1)c1ccc2c(c1)OCO2 +CCOCCCNC(=O)Nc1ccc(C)cc1OC +CSc1nc(N)nc(SCc2ccc(F)cc2)c1C#N +Cc1ccc(NCC(O)C(O)C(O)CO)cc1C +CCNC(=O)c1ccc(NC(=O)c2cccc(OC)c2)c(C)c1 +Cc1ccc(-c2cncc(-c3cc(NCCCO)nc(C)n3)c2)cc1 +COc1cccc(OC)c1OCc1cccc(C(N)=O)c1 +Cc1ccccc1CCC1CCCN(C(=O)c2cn[nH]c2)C1 +CSc1ccc(CCC(=O)N2CCc3ncncc3C2)cc1 +Cc1ccc(N2CCc3onc(-c4ccc(F)c(F)c4)c3C2)nn1 +CCC(=O)c1cc2c(cc1NC(=O)c1cccc(OC)c1)OCCO2 +Cc1ccc(CCC(=O)Nc2cccn(C)c2=O)cc1 +Cc1csc(CCCCNC(=O)c2cc(-c3ccccc3)no2)n1 +c1cncc(CCCn2ccc(-c3cccc(-c4cncnc4)c3)n2)c1 +O=C(Nc1cccc2cn[nH]c12)c1ccc(=O)n(-c2ccc(F)cc2)c1 +Nc1cccc(CCC(=O)N2CCN(c3ccccc3)CC2)c1 +CC(C)CCC(=O)NCCCc1nc2ccccc2[nH]1 +c1ccc(Cc2nnc(NCCc3nnc4ccccn34)s2)cc1 +COc1ccc(COC(=O)c2c(C)nn(C)c2C)cn1 +N#Cc1ccc(-c2noc(-c3cc(-n4cccn4)ccn3)n2)nc1 +CN(C)C(=O)CN(Cc1ccc(Cl)c(F)c1)CC(F)(F)F +CNC(=O)c1cc(OC2CC2)cc(C(F)(F)F)n1 +CCOC(=O)C(NCC(F)(F)F)c1cc(F)ccc1F +CCCOc1ccc2c(c1)CCNC2C1CC(=O)C1 +CCCN(CCC)C(=O)Cn1cc(C#N)c2ccccc21 +Cc1c(Cl)cccc1N(C)S(=O)(=O)c1cccc(N)c1 +CCOC(=O)C(C)(NC)c1ccc(S(C)(=O)=O)cc1 +N#CCCN1CCN(C(=O)COc2ccccc2Cl)CC1 +COc1c(C)cc(C)cc1S(=O)(=O)N1CCCC(=O)C1 +CCOC(=O)N1CCN(CC(O)COC(C)(C)C)CC1 +CN(Cc1ccccc1)CC(O)c1ccccc1F +O=C(Nc1nnc(C2CC2)s1)NC1c2ccccc2CC1O +CN(CC(=O)Oc1ccc(-c2ccc(C#N)cc2)cc1)S(C)(=O)=O +Cc1nc(S(=O)(=O)N(C)CC2(C)CCOCC2)cn1C +O=C(Cc1ccccn1)N1CCc2ncnc(-c3ccncc3)c2CC1 +COc1ccc(CCc2nnc(NC(=O)c3cccs3)s2)cc1 +COCC(=O)NCCC1CCN(C(=O)c2ccc(F)cc2)CC1 +O=C(C1CCCC1)N(CC1=CC2N=CC=C2C=C1)C1CC1 +O=C(Nc1cnc2n1CCCC2)c1ccc2c(c1)ncn2CCO +CN(Cc1ccccc1)C(=O)c1ccc2ccnn2c1 +CC(=O)N1CCN(C(=O)CCNc2c(F)cc(C#N)cc2F)CC1 +COCC(C)n1c(C)cc(C(=O)CSc2n[nH]c(N)n2)c1C +Cc1nc(N2CCCC2)nc(-c2ccncc2)c1C +CC(=O)NCCNC(=O)CCC1Cc2ccccc2NC1=O +Cc1cccc(C(=O)Nc2nnc(-c3cc(C)n(C)n3)o2)c1 +O=C(Cc1ccsc1)Nc1ccc(C(=O)NC2CC2)cc1 +COC(=O)c1cccn2cc(-c3ccc(F)cc3)nc12 +Cc1ccc(C)c(NC(=O)C2CC(=O)Nc3nc(C)nn32)c1 +COc1ccccc1C(=O)NCc1cc(-c2cccs2)n(C)n1 +CCC1C(=O)Nc2ccc(C(O)c3ccco3)cc21 +Cn1cnnc1-c1cccc(NC(=O)c2cc(F)cc3[nH]cnc23)c1 +O=C(NCCCOCC1CCCO1)c1cnns1 +CC(=O)N1CCN(C(=O)CSc2nncn2C)CC1 +O=C(c1ccc(Cl)cc1)N1CCN(c2ccccn2)CC1 +CCNC(=O)N1CCc2nc(NC(=O)C3CCC3)sc2C1 +C#CCN(CC1CCCO1)C(=O)NC(C)Cn1cncn1 +CC(C)On1c(SCC(=O)N(C)C)nc2ccccc2c1=O +CCCC(=O)N1CCC(C(=O)NCCC(=O)NC2CCCC2)CC1 +O=C(N1Cc2nn3nccnc3c2C1)C1(c2ccccc2)CCCC1 +COC(=O)NCC(=O)N1CCN(Cc2ccco2)CC1 +CCc1ccc(-n2nnnc2C=CN2CCCCC2)cc1 +O=C(Cn1cc(C(=O)n2ccnc2)cn1)N1CCCCC1 +CCCn1ncc2nc(-c3ccc(OC)c(O)c3Cl)[nH]c21 +COc1ccc(NC(=O)CNC(N)=O)cc1Cl +Cn1cc(C(=O)OCC(=O)N2CCSc3ccccc32)cn1 +CC(C)c1cc(C(=O)NCc2noc(-c3ccsc3)n2)nn1C +CC(=O)Oc1ccccc1-c1nnc(-c2ccccc2)o1 +Cc1noc2nc(C3CC3)cc(C(=O)NCc3ccccc3Cl)c12 +COCC(C)NC(=O)Nc1cccc(N2CCCCCC2)c1 +Cc1ccc(NC2C(=O)Nc3ccccc32)cc1C +CC(=O)Nc1ccc(OC(=O)c2ccc3nc(C)c(C)nc3c2)cc1 +Cc1nc2scc(C)n2c(=O)c1NC(=O)COc1ccc(F)cc1 +CCc1nn(C)c(CC)c1CN1CCC(S(=O)(=O)NC2CC2)C1 +CCc1nc2n(n1)CCCC2NC(=O)c1cc(OC)cc(OC)c1 +O=C(NC1CCc2ccccc21)c1cc(F)c(F)c(F)c1F +COc1cc(C(=O)N2CCCC(c3ccn[nH]3)C2)c2ccccc2n1 +O=C(Cn1nc(-c2ccco2)ccc1=O)c1ccc(Cl)cc1 +CC(C)N(CCO)c1ccc(N)c(C(F)(F)F)c1 +CCn1c(Cn2c(-c3ccccn3)noc2=O)nc2c(F)cccc21 +CC(C)CN(C)S(=O)(=O)c1ccc2c(c1)oc(=O)n2C +CN(CC(=O)Nc1nccs1)Cc1ccc(Cl)cc1Cl +COC(=O)c1ccc(OCc2nc(C)no2)c(OC)c1 +COCCC1CN(c2ncnc3sc4c(c23)CCNC4)CCO1 +Cc1cccc(C(C)C)c1NC(=O)N1CCOCC1C1CC1 +CCC(NC(=O)NCc1ccnn1C)c1cccc(Cl)c1 +Cc1cc(NC(=O)NCCc2ccc(O)cc2)nn1C +COC(=O)NCCC(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +Cc1sc(C(=O)NCC(=O)NC2CC2)cc1-c1ccc(F)cc1 +Cc1nc(C#N)c(NCc2ccc3c(c2)OCO3)o1 +CC(=O)OCC(=O)Nc1ccccc1OC(F)F +C=CCN(Cc1cccs1)C(=O)NCc1ccnc(OC)c1 +CC(C)c1nnc(NC(=O)c2cn(CC(=O)N(C)C)nn2)s1 +CCS(=O)(=O)NCCNC(=O)c1ccc(O)c(Cl)c1 +COc1cc(N)ccc1NC(=O)C12CC3CC(CC(C3)C1)C2 +Cc1cc2cc(NC(=O)c3cccc(C(N)=O)c3)ccc2[nH]1 +NC(CS(=O)(=O)c1ccc(F)cc1)c1ccncc1 +Cn1c(SCC(N)=O)nnc1-c1csc2ccccc12 +Cc1ccc(-c2noc(CCc3nc4ccc(C)c(C)c4[nH]3)n2)nn1 +CC1CCN(c2cc(NC(=O)Nc3ccc(F)cc3F)ncn2)CC1 +CC(Nc1ncnc2c1cnn2CCO)C(=O)N1CCCCC1 +CCCNC(=O)C1CCCN(C(=O)C(C)Sc2ccccn2)C1 +COC(=O)CCCC(=O)c1cc(Cl)c(Cl)cc1O +CC1CN2CCCC2CN1C(=O)c1scnc1C1CC1 +CCCNC(=O)C(C)Oc1cccc(Br)c1 +CCCS(=O)(=O)NCCc1ccc(S(N)(=O)=O)cc1 +COc1cc(C)sc1C(=O)Nc1ccc2oc(=O)[nH]c2c1 +CC(C)CNc1ncnc2c1nnn2Cc1ccccc1Cl +Cn1cc(CCCSc2nnnn2CC2CCCO2)cn1 +CC1CC1C(=O)Nc1nc(-c2cccc(O)c2)cs1 +COc1ccc2c(c1)CCCN2C(=O)CN1CCCC1=O +Cc1cc(NC(=O)NC2CCCC2C)ccc1C(=O)NC(C)C +COc1cc(F)ccc1NCc1cc(OC)c2c(c1)OCO2 +CCc1ccccc1N1CC(C(=O)OCC2CCCCO2)CC1=O +Cc1cc(C)n2cc(CSc3ncnc4ccsc34)nc2n1 +O=C(NCC(=O)N1CCc2nocc2C1)NCc1ccccc1 +Cc1cc(C(=O)Nc2cccc(-n3cccc3)c2)n(C)n1 +COc1ccc(C2=CCN(C(=O)c3cccc4cn[nH]c34)CC2)cc1 +O=C(NCc1ccco1)c1ccc2c(c1)[nH]c(=O)c1ccncc12 +Cc1nonc1C(=O)Nc1cc(Cl)ccc1C(=O)N1CCCC1 +Cc1cc2c(cc3c(=O)n(CC(=O)NC4CCCCC4)nc(C)n32)o1 +Cc1nn(C)c2ncc(NC(=O)N3CCCC(C)CC3)cc12 +Cc1cccc(-c2noc(C(=O)N3CCC(C)CC3)c2N)c1 +CCCC1=C(C(=O)OC)C(c2cc(OC)ccc2OC)NC(=O)N1 +Cc1cccc(NC(=O)Cc2cccc(C(F)(F)F)c2)n1 +CC(=O)Nc1cc(C(=O)NCc2ccccc2C)ccc1C +CC(C1CC1)N(C(=O)c1cn(C)c2ccccc12)C1CC1 +O=C(c1cc(-c2ccco2)[nH]n1)N1CCN(C2CCCC2O)CC1 +CC1=NC(C)CNc2c1c(=O)n(C)c1ccccc21 +CN(C(=O)CSc1nnc(-c2cccnc2)n1C)c1ccccc1 +CCCn1ccc2oc(C)c(C(=O)NCc3ccccc3)c2c1=O +COCc1ccc(C(=O)N2CCc3ccc(Cl)cc3C2)cc1 +O=C(NCc1cccnc1)c1ccc(Cn2cccn2)cc1 +CC(C)N1CC(F)C(OCc2nc3ccccc3[nH]2)C1 +CCCCN(CC)C(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +Cc1csc(NC(=O)C2CC(=O)N(c3ccccc3F)C2)n1 +CCC(C)(C)C(=O)Nc1ccc(N2CCNC(=O)C2)nc1 +CN(Cc1nccn1C(F)F)C(=O)Nc1cc(F)ccc1F +CCCOC1CCCN(C(=O)c2cc(C(C)=O)c[nH]2)C1 +COCCNC(=O)c1ccccc1NC(=O)c1ccncc1 +CCCCn1c(CCNC(=O)c2ccco2)nc2ccccc21 +CCOc1ccc(C2CCCN2C(=O)NCc2ncn(C)n2)cc1 +COC1CCCC(OC(=O)C2CCCN2C(=O)c2cccs2)C1 +CCCNC(=O)CNC(=O)Nc1ccccc1Br +O=C(NCc1ccncc1)Nc1ccccc1OC(F)F +Cn1nc(CC(=O)Nc2ccccc2O)c2ccccc2c1=O +Cc1cc2c(=O)n(CC(=O)NC3CC3)ccc2s1 +COCc1nc(C(=O)N2CCN(c3ccc(C#N)cn3)CC2)cs1 +CN(C)C(=O)N1CCC(C(=O)Nc2ccccc2C(N)=O)CC1 +CCCNC(=O)CN1CCc2nc(NC(=O)c3ccoc3)sc2C1 +Cc1cc(=O)[nH]c2sc(C(=O)c3ccc(F)cc3)c(N)c12 +OCc1nnn(Cc2ccccc2Cl)c1C1CC1 +COc1ccc(-c2noc(N(C)Cc3ccccc3)n2)cc1 +O=C(CCNC(=O)c1ccc(F)cc1F)Nc1ccc2[nH]ncc2c1 +COCCN1CCN(C(=O)CCCc2ccccn2)CC1=O +Cc1nc(-c2cc(C(=O)Nc3c(C)noc3C3CC3)cs2)cs1 +Cc1ccc(CNC(=O)N2c3cccnc3N(C(C)C)C(=O)C2C)o1 +CC(C)CNC(=O)CNC(=O)N1CCN(c2ncccn2)CC1 +CCC(CC#N)NC(=O)c1cccc(C(F)(F)F)c1 +Cc1c(C(=O)Nc2ccc3c(c2)OCO3)nnn1Cc1ccccc1 +CC1CCCC(NC(=O)C2CCCN(C(=O)C3CC3)C2)C1 +CC(=O)NC(C)(C)c1noc(-c2ccn(-c3cccc(F)c3)n2)n1 +COc1ccc(F)cc1NC(=O)c1ccc(-n2cccn2)cc1 +N#Cc1c(NC(=O)COc2ccc(F)cc2F)sc2c1CCC2 +COc1ccc(-c2ccc(CCC(=O)OCC#N)o2)cc1 +Cc1ccccc1Cn1nnc(CO)c1-c1ccc(F)cc1 +COc1ccc(CCC(C)(C#N)N2CCCC2)cc1OC +Fc1ccc(C=Cc2nn3c(-c4cnccn4)nnc3s2)cc1 +CCNC(=O)Nc1ccc(C(O)C2COCC(=O)N2)cc1 +CCC(NS(=O)(=O)c1ccc(Br)cc1)C(=O)N(C)C +COc1ccc(F)cc1-c1cc(CO)c(=O)[nH]n1 +Cc1ccccc1NC(=O)c1ccc(S(=O)(=O)NC(C)C)cc1 +CCOc1ccc2c(c1)C(c1c(C)ncnc1C)NCC2 +Cc1nn(C)c2ncc(NC(=O)c3cc(Cl)ccc3F)cc12 +CN(C)c1ccc(S(=O)(=O)N(C)C)cc1NC(=O)c1cc[nH]n1 +CCCNC(=O)CCCC(O)c1cc(F)ccc1F +COc1cc(CCNC(=O)CSc2nncs2)ccc1C +O=S1(=O)N=C(NCC(F)(F)F)c2ccccc21 +CCC(C(=O)N1CCCCCC1)N(c1ccccc1)S(C)(=O)=O +COc1ccc(N)cc1-n1cc(-c2ccc(N(C)C)cc2)nn1 +Cc1ccc2c(c1)nc(CO)n2CC(=O)NC1CCCC1 +CC1NCc2ccccc2C1C(=O)NCC1CCCO1 +CCC(C)NC(=O)CSc1nc(=O)[nH]c(C)c1C(=O)OC +CCNC(=O)Cn1c(-c2ccc(OC)c(OC)c2)nc2ccccc21 +O=C(NCCSc1ccccc1)c1ccc(N2CCOCC2)nc1 +O=C(c1ccccc1)n1nc(-c2cccnc2)nc1NCc1ccco1 +O=C(NCc1cc(-c2ccco2)on1)c1cc2sccc2[nH]1 +O=C(Nc1ccnn1C1CCCCC1)c1cncc(Br)c1 +O=C(OCc1ccccn1)c1ccc(-n2cncn2)c(F)c1 +CCc1ccc(CNC(=O)Nc2cc(NC(C)=O)ccc2F)s1 +COc1cc(CNCC(=O)NC(C)(C)C)cc(Cl)c1OC +CCc1ccc(C2COCCN2CCn2c(=O)oc3cccnc32)o1 +Cc1nc(C)n(CC2CN(CC(=O)NC3CCCC3)CCO2)n1 +CNC(=O)c1cccn(-c2ccc(NC(=O)c3ccccc3)cc2)c1=O +CCOC(=O)c1sc2ncnc(NC)c2c1C +OCC(c1ccccc1)C1NCCc2cc3c(cc21)OCC3 +CC(C)NC(=O)CNc1ccccc1OC(F)(F)F +Cc1cc(C)cc(NC(=O)C(C)Sc2nnc(C3CC3)n2C)c1 +Cc1nc2ccc(NC(=O)CCNC(=O)c3cccs3)cc2o1 +CNc1ccc(C(=O)N(C)c2ccc(F)cc2)cc1 +Oc1ccc(Cl)c2c1CCNC2c1cnn2ccccc12 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(F)c(Cl)c1 +COc1cccc(-n2c(SCC(N)=O)nc3ccccc3c2=O)c1 +CC1Cc2ccccc2N1C(=O)C1CCN(C(=O)C2CC2)CC1 +CCc1cc2c(SCC(=O)NCc3ccccc3)ncnc2s1 +CCC1CN(Cc2cc(F)c(F)cc2F)CC(C)O1 +COCc1cc(C(=O)N2CCCCCC2c2ccncc2)ccc1F +CCn1cc(NC(=O)c2ccc(C)cc2C)ccc1=O +CNC(=O)c1cccnc1S(=O)Cc1ccccc1 +Cc1cc(-c2csc(NC(=O)c3cccnc3)n2)c(C)o1 +COC(=O)CN(C(C)C)S(=O)(=O)c1c(C)c(C)cc(C)c1C +CCOC(=O)CCC(C)NC(=O)N1CCC2(CCCC2)CC1 +Cn1ncc(C(=O)Nc2cc(F)c(F)c(F)c2)c1-n1cccc1 +CC(NC(=O)NCCc1nnc2n1CCCCC2)c1ccccc1 +Nc1ccc(SCC(=O)Nc2ccc(S(N)(=O)=O)cc2)cn1 +COCc1cc(C)nc2sc(C(=O)Nc3ccccc3O)c(N)c12 +COc1cc2c(cc1OC)CN(C(=O)Cc1ccccc1F)CC2 +N#Cc1ccc(CCC(=O)Nc2ccnc3ccncc23)cc1 +O=C(Cn1cc(Br)cn1)c1cc(F)ccc1F +O=C(Cn1nnc2ccccc21)Nc1ccc(OC(F)(F)F)cc1 +O=C1C2CC(O)CCN2C(=O)CN1CCCn1ncc2ccccc21 +COC(=O)CN(C)C(=O)c1ccc(O)c(Cl)c1 +CCC(CC)NC(=O)C(C)Sc1nncn1-c1ccccc1 +COc1ccc(CNC(=O)N2CCCC2c2nc(C3CC3)no2)cc1 +CN1c2cnc(N)nc2-c2sccc2S1(=O)=O +CC(=O)N1CCc2ccc(NC(=O)Cc3cccs3)cc21 +COCCN(Cc1ccccc1)C(=O)NC1CCCC1 +Nc1cccnc1S(=O)CC(=O)NCC(F)(F)F +CC(NC(=O)CSc1nncn1Cc1ccco1)c1ccccc1 +CSc1ccccc1C(=O)NCCC(O)c1ccc2c(c1)OCO2 +CC(NC(=O)COc1ccc(F)cc1F)c1ccc2c(c1)OCO2 +Cc1ccc(C(=O)Nc2nc(-c3ccc(Cl)cc3)cs2)cn1 +COc1ccc(C(O)CCC(=O)NC2CCCCCC2)cc1 +CCOc1ccc(NC(=O)C(C)Nc2cccc(CO)c2)cc1 +Cc1cc(-c2nnc(NC(=O)Cc3ccc(Cl)cc3)o2)c(C)o1 +Cc1ccc(-c2cnn(CCN3CCOCC3)c2)s1 +O=C(OCC(=O)N1CCc2ccccc2C1)c1ccc2c(c1)CCC2 +CC(NC(=O)Nc1ccccc1F)c1ccc2c(c1)OCO2 +CC(=O)c1ccc2c(c1)N(C(C)C)C(=O)C(C)(C)O2 +N#Cc1cccc(OCC(=O)c2c[nH]c3ccccc23)c1 +O=C(c1ccccc1)N1CCN(Cc2cc(-c3ccco3)on2)CC1 +Cc1cccc(C)c1NC(=O)c1ccc(C(F)(F)F)nc1 +NC(=O)c1ccc(OC(C(=O)NC2CC2)c2ccccc2)cc1 +Cc1nc2cc(NC(=O)CCCc3cccs3)ccc2o1 +COc1ccc(C(=O)COc2ccc(C)cc2N)c(C)c1 +Cc1ccccc1NC(=O)CC1C(=O)N=C2Nc3ccccc3N21 +COc1cccc(C(=O)NC(C)CN2CCCC2=O)c1 +COc1ccc(Cl)c2c1CCNC2c1scnc1C +Cc1ccc(OC(C)C(=O)N(C)Cc2cc(C)on2)cc1 +O=C(Cc1ccc(O)cc1)Nc1ccc(F)c(F)c1 +Cc1ccc(C(=O)c2ccccc2C(=O)N2CCn3cncc3C2)cc1 +CC(C)COc1cccc(-c2cnn(C)c(=O)c2C#N)c1 +CCCCCS(=O)(=O)N1CCN(c2nc(CC)ns2)CC1 +CS(=O)(=O)c1ccccc1NC(=O)c1cc(Cl)cc(Cl)c1 +CC1CN(C(=O)CCc2ccccc2N)CC(C)O1 +Cc1ccc(C(=O)N2CCN(C(=O)C3CCCO3)CC2)cc1 +CC(C)(C)C(=O)NCC(O)c1ccc2c(c1)CCCC2 +O=C(NCCOc1cccc(Cl)c1)NC1CCCc2occc21 +CCN1CC(NC(=O)c2oc3cc(C)ccc3c2C)CC1=O +Cc1cc(C(=O)NC(C)c2ccccc2Cl)n(C)n1 +COc1cccc2c1CCN(C(=O)NCC(C)(C)c1ccncc1)C2 +Cc1ccc(-n2ncc(C(=O)N(C)CCC#N)c2C(F)(F)F)cc1 +Cc1ccc(CS(=O)(=O)NCc2ccccc2-n2ccnc2)cc1 +CN(CC(F)(F)F)C(=O)CN1CCN(c2nccs2)CC1 +O=C(Nc1cccc(C(=O)N2CCCCC2)c1)c1ccccc1 +Cc1cccc2c(CC(=O)NC(C)c3nnc4ccccn34)c[nH]c12 +CCn1nccc1C(=O)NCc1ccc(OC)c(OC)c1 +COc1ccc(CCNC(=O)CNc2cccc3c2OCCO3)cc1 +CC(CC12CC3CC(CC(C3)C1)C2)NC(=O)CNC(N)=O +COc1ccc(NC(=O)CC(NC(C)=O)c2cccs2)cn1 +Cc1cc(C)n(C2CCN(c3ccc(F)cn3)C2)n1 +CC(C)(CO)NS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +CC(C)CN(C(C)C)S(=O)(=O)c1ccc2c(c1)CCC2 +CCc1ccc(S(=O)(=O)N(CC(=O)OC)C(C)C)s1 +O=C(CC1C=CCC1)N1CCN(c2ncccn2)CC1 +OCCC(c1ccc(F)cc1)c1ccc2c(c1)OCO2 +COC(=O)c1cccc(NS(=O)(=O)c2ccc(OC)c(C)c2)c1 +Cn1cc(CNS(=O)(=O)c2c(F)cccc2F)cn1 +CN(Cc1cccc(F)c1F)Cc1nccn1C(F)F +O=C(Cc1ccc(-n2cccn2)cc1)N1CCCC1Cn1cccn1 +Cc1nn(C)c(C)c1CCC(=O)NC1(C)Cc2ccccc2C1 +COc1ccc(CCNC(C#N)c2ccco2)cc1 +CCc1nn(C)c(CC)c1CNC(=O)NCc1nc(C)c(C)s1 +O=c1ccc(-c2nnco2)cn1Cc1cccc2cccnc12 +Cc1csc(N2CCN(C(=O)C3CCCN(C(N)=O)C3)CC2)n1 +COCC(O)CN(C)C(=O)Nc1nc(C)cs1 +Cc1nc(C)c(C(=O)NC(Cc2ccccc2)C2CC2)s1 +COC(=O)c1ccc(C(=O)N2CCCCCC2c2cccn2C)nc1 +CCC(C)N(C)C(=O)Nc1ccccc1CC(N)=O +CC=CCCNC(=O)NCC(C)(C)C(O)C(C)C +COC(=O)CN(C(=O)c1nc2nc(C)cc(C)n2n1)C(C)C +CC1CN(C(=O)CCCS(=O)(=O)N2CCCC2)C(C)CO1 +CC(C)NC(=O)CNC(=O)c1ccc2c(c1)CCCC2 +CCCNC(=O)CCNC(=O)Nc1cccnc1-n1cncn1 +Cc1nsc(NC(=O)NCC(=O)c2c[nH]c3ccccc23)n1 +O=C(NCCCc1ccccn1)c1cccc(Cn2cccn2)c1 +Cc1nccn1-c1ccc(CNC(=O)N2CCCC(C)C2)cc1F +CCC1CCC(NC(=O)COc2ccccc2)CC1 +CCN(CC)C(=O)CCC(=O)NC1(C)CCC(C)CC1 +Cc1csc(-c2cc(S(=O)(=O)NC(C)(C)C)c(C)n2C)n1 +COC(=O)C1OC2(OC1C(=O)OC)c1ccccc1-c1ccccc12 +O=C(CCOc1ccccc1)Nc1cccc2c1NCCC2 +CC(C)(C(=O)NCCCN1CCCC1=O)c1ccccc1 +COc1ncccc1CNC(=O)NCCOc1ccc(C)cc1C +O=C(CCNc1ncnc2sccc12)N1CCOCC1 +O=C(Nc1nnc2n1CCS2)c1ccccc1C(F)(F)F +Cn1cc(Br)c(-c2ccc(N)cc2)n1 +O=C1CN(C(=O)c2cnns2)c2ccccc2N1 +Cc1cc(C(=O)Nc2nc3c(C)ccc(Cl)c3s2)no1 +COc1cc(C(=O)Nc2ccc(C(C)=O)cc2)ccc1OC(C)=O +COC(=O)C1CCN(C(=O)Nc2ccccc2OC)CC1 +Cc1ccc(-c2ccc(=O)n(C(C)C(=O)NCc3ccncc3)n2)cc1 +CN1CC(C(=O)N(C)Cc2ccc(F)c(F)c2)CC1=O +Cn1c(NC(=O)c2ccc3c(c2)OCO3)cc(=O)n(C)c1=O +CCCC(=O)N1CCCC(c2nc(C(C)CC)no2)C1 +C=CCNC(=O)C(C)Nc1ccc2[nH]c(=O)[nH]c2c1 +NC(=O)c1ccc(NCC(=O)N2CCc3sccc3C2)cc1 +O=C(NCCc1cccs1)c1cc(Cl)c2c(c1)OCO2 +CNS(=O)(=O)c1ccc(C(=O)N2CCN(CC(C)(C)O)CC2)o1 +Cc1nc(Nc2cccc(F)c2)[nH]c(=O)c1CCO +Cc1cc(C(=O)Nc2nc(-c3ccccc3)cs2)no1 +N#CCCCCN1C=Nc2ccccc2S1(=O)=O +CCCc1nnc(SCC(=O)NC(C)CC)n1N +CCCOc1ccc(Cl)cc1NC(=O)NCc1ccnn1C +NC(=O)CN1C(=O)C=C(c2ccc(F)cc2)Nc2ccccc21 +Cc1cccc2[nH]cc(CC(=O)NCCCNS(C)(=O)=O)c12 +O=C(c1ccc(O)cc1)N1CCN(CCO)CC1 +COc1cc(NC(C)=O)ccc1NCCc1cccs1 +O=C(c1cc[nH]n1)N1CCC2(CC(c3ccccc3)CO2)C1 +COCCCNC(=O)C1(C)CCC(=O)N1c1ccccc1C +c1ccc(-n2cc(NCc3ccc(OCC4CCCO4)cc3)cn2)cc1 +CCOC(=O)CCNc1ccccc1Br +CC(=O)Nc1ccccc1OCC(=O)Nc1cccc(C)c1 +COc1ccc(SC(C)C(=O)NC(C)CO)cc1 +COc1ccc(CNC(=O)c2ccc3cc[nH]c3c2)cc1OC +Cc1ccc(Br)cc1NS(=O)(=O)c1c[nH]nc1N +CCOc1ccc(NC(=O)NCc2cc(C)no2)cc1Cl +CN(C)c1ccccc1C#CCNC(=O)c1ccc2[nH]cnc2c1 +Cc1ccc2nnc(C#N)c(Nc3cccc(C(N)=O)c3)c2c1 +CC(C)(C)C(=O)Nc1ccccc1C(=O)NCc1cccc(F)c1 +CCCNC(=O)CN(C)C(=O)c1ccn(-c2cccc(Cl)c2)n1 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)NCCCC(N)=O +CCC(=O)Nc1cc(F)ccc1C(=O)NC(C)C(=O)OC +CC(C)CCOC1CCCCC1NC(=O)c1cccc(NC(N)=O)c1 +CCCNC(=O)CCOc1cccc(Br)c1 +CCOc1c(Cl)cc(C(=O)NC2CCC(O)CC2)cc1OC +Cc1ccccc1CC(=O)NCc1ccc2c(c1)OCO2 +CCn1c(CCCNC(=O)C2CC2)nc2ccccc21 +COc1ccc2c(c1)CCCC2CC(=O)NCCCC(N)=O +Cc1nc2nc(-c3cccnc3)nn2c(N)c1C#N +Cc1ccc(C(=O)N2CCCC(C(=O)Nc3nccs3)C2)cc1 +N#Cc1nc(C=Cc2cccs2)oc1N1CCC(C(N)=O)CC1 +O=C(Nc1ccccc1)Nc1cc2c(oc1=O)CCCC2=O +Cn1ncc(NC(=O)c2ccc(F)cc2)c(N2CCCCC2)c1=O +COc1ccc(CNC(=O)CC(C)(C)C)cc1NC(C)=O +Cc1noc(C)c1N(C)C(=O)c1c[nH]c2cccc(F)c12 +CCc1nsc(N2CCCN(C(=O)CCC3CCCO3)CC2)n1 +CCCc1noc(CNc2cccc(C(N)=O)c2C)n1 +CC1CCc2noc(NC(=O)c3ccccc3Cl)c2C1 +CC(Cc1cnccn1)NC(=O)C1(c2ccc(F)cc2)CC1 +CC(C)CNC(=O)C(C)Sc1ccc(F)cc1 +O=C(Nc1cc(N2CCOCC2)ncn1)c1ccc(F)cc1Cl +Cc1c(C(=O)N(C)Cc2ccc3ncccc3c2)cnn1C +COC(=O)CCCc1ccc2c(c1)N(C(C)=O)CC(C)(C)O2 +COC(=O)c1ccc(F)c(S(=O)(=O)N2CCCC(C)C2)c1 +CCN(CC)C(=O)c1ccc(C(=O)N(CC)CC)cc1 +COCc1ccccc1CNC(=O)c1cc(C)ccc1C +CC(CCC1CCCO1)NC(=O)c1ccc[nH]c1=O +O=C(c1c[nH]c2cccc(F)c12)N1CCCC2(CC=CCC2)C1 +CC(C)c1nnc2n1CCN(Cc1ccccc1Oc1cccnc1)C2 +CC(C)(CNC(=O)CCn1c(=O)oc2ccccc21)c1cccs1 +COc1ccccc1CNC(=O)CN(C)CCC#N +Cc1ccsc1C(=O)N1CCN(c2ccccc2)CC1 +Cc1nc(-c2ccc(NC(=O)N3CCCC(C)C3CO)cc2)cs1 +COc1ccccc1C(=O)CSc1nnc(-c2cnccn2)n1C +COc1ccc(-c2noc(CNc3ccccc3C(N)=O)n2)cc1 +O=S(=O)(NCCC(O)C1CC1)c1ccccc1Cl +Cc1ccccc1C1CC1C(=O)N(CC1CCCO1)c1ccncc1 +C=CCc1c(N2CCN(C(=O)OCC)CC2)[nH]c(=O)n(C)c1=O +O=C(NCC1(c2ccccc2F)CC1)Nc1cccnc1 +CCC(C)NC(=O)COc1cc(=O)n(CC)c2ccccc12 +O=C(C1CC=CC1)N1CC2OCC(=O)N(Cc3ccncc3)C2C1 +O=C(NCc1cccs1)c1cc(COc2ccccc2)[nH]n1 +CC(C)Cn1nccc1NC(=O)C1CC2CCC1C2 +CC(C)(CNC(=O)c1cc(-c2ccccc2)on1)c1ccncc1 +CC(NC(=O)c1ccccc1)C(=O)N1CCN(c2ccccc2)CC1 +CC(=O)Nc1ccc(F)c(NC(=O)NCc2cc(C#N)ccc2F)c1 +COc1ccc2c(c1)CCCN2C(=O)c1cccnc1N1CCCC1 +Cc1cc(C(=O)NC2CCN(c3ncccc3C#N)CC2)on1 +Cc1cc(C)cc(C(=O)NC2CCN(c3ccccc3)C2=O)c1 +CCCNC(=O)CCNC(=O)Nc1cc(Cl)ccc1F +C=CCNC(=O)C1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +O=C(COc1ccc(NC(=O)C2CC2)cc1)NCc1cccs1 +COCN1C(=O)CNc2cc(Cl)c(Cl)cc21 +COC(=O)Nc1ccc(S(=O)(=O)NCC2CCCO2)cc1 +OCc1ccc(CNc2ccccc2OCc2cscn2)o1 +Cc1occc1C(=O)N1CCSc2ccc(N)cc21 +Cc1ccc(NC(=O)c2ccc3[nH]c(C(F)F)nc3c2)c(O)c1 +O=C(c1ccccc1O)N1CCCC(C(=O)N2CCOCC2)C1 +CCOC(=O)N1CCN(C(=O)c2ccccc2)CC1 +Cc1cc(C)cc(-c2nc3ccc(-n4cnnc4)cc3o2)c1 +CC(C)CN1C(=O)C2(CCN(S(C)(=O)=O)C2)c2ccccc21 +N#Cc1ccc(CNC(=O)N2CC3CC=CCC3C2)c(F)c1 +CCc1onc(C)c1NC(=O)Nc1c(C)nn(CCOC)c1C +O=S(=O)(c1ccc(OCCn2cnnn2)cc1)N1CCOCC1 +CC(C)NC(=O)Cc1ccc(NCc2nnc(C(C)(C)C)o2)cc1 +COc1cc(CC(=O)Nc2c(C)n[nH]c2C)cc(OC)c1OC +CCN(CCO)C(=O)c1ccc(C)c(NC(=O)c2ccccc2)c1 +OCCOc1cccc(-c2[nH]cnc2-c2ccccc2)c1 +CCc1nc2nc(C)c(CC(=O)NCc3ccccc3)c(C)n2n1 +CCCOc1ccc(CNC(=O)NCc2cnc(C)s2)cc1 +CN(C)C(=O)CN1CCN(c2ncnc3[nH]ncc23)CC1 +O=C(Cc1ccccc1)NCC(=O)Nc1ccnn1C1CCCCC1 +O=c1[nH]cccc1-c1nc(-c2ccc(C(F)(F)F)cc2)no1 +Cc1cnn(CCCNC(=O)C2COc3ccccc3C2)c1 +NC(=O)CCN(Cc1ccccc1)C(=O)c1cccc(-n2cccn2)c1 +Cc1c(-c2ccncn2)cnc2nc(-c3ccc4c(c3)OCCO4)nn12 +COCCn1c(SCC2(O)CCCCC2)nnc1-c1ccncc1 +COc1cc(C(=O)NC(C)c2ccc(C)c(F)c2)cc(OC)c1OC +CCc1nc(CNC(=O)C2CCOc3ccccc3C2)cs1 +COc1cc(C)c(C(=O)OCc2nc3ccccc3[nH]2)cc1OC +Cc1cc(NC(=O)CSc2nnnn2C2CC2)ccn1 +O=C(NCc1noc(-c2ccco2)n1)OCC(F)(F)F +COCc1ccc(C(=O)OC(C)c2nc(C)no2)o1 +N#Cc1ccc(CNc2ncccc2C(N)=O)cc1 +Cc1cc(Nc2nc(-c3cc(C)n(C4CC4)c3C)cs2)n(C)n1 +CCN(CC(C)C#N)S(=O)(=O)c1ccc2c(c1)CCO2 +Cc1ccc(S(=O)(=O)NCCCOC2CCCC2)s1 +CC(C)N(C(=O)Cn1c(=O)oc2ccccc21)C(C)C +CCN(CCc1ccncc1)C(=O)c1ccccc1N +Cc1ccc(OCC(O)Cn2nnnc2C(C)(C)C)c(C)c1 +CCC(C(=O)OC)C(O)c1ccc(OC(C)C)cc1 +O=C(NCc1noc2ccccc12)NCC1CCCO1 +CCC(Sc1nc(C)c(C)c(=O)[nH]1)C(=O)OC +CC(=O)Nc1cccc(NC(=O)NC(CCO)c2ccccc2)c1 +Cc1nc(CN2CCN(C(=O)c3cccs3)CC2)oc1C +COC(=O)Nc1cccc(NC(=O)NC2CCCCCC2CO)c1 +CCc1n[nH]c(SCC(=O)NC(C)c2n[nH]c(C)n2)n1 +CCC(=O)N1CCCN(Cc2cnc(C(C)(C)C)s2)CC1 +Cc1nc(-c2cc3c4c(c2)CC(=O)N4CCC3)cs1 +COc1ccc(-c2noc(Cn3nnc4ccccc43)n2)cn1 +COC(=O)COc1cccc(NC(=O)Cn2cncn2)c1 +Cc1ccnc2nc(C(=O)Nc3ccc4oc(N(C)C)nc4c3)nn12 +O=C1CN(C(=O)Cn2nnc3ccccc32)c2ccccc2N1 +Cc1cccc(NC(=O)CCCc2nc(-c3ccccn3)no2)c1C +Cc1ccncc1NC(=O)N(C)C(C)Cc1cccs1 +O=C(c1ccccc1)N1CCCN(c2cccc(C(F)(F)F)n2)CC1 +CN(CCc1ccccc1)c1cnn(CC2CC2)c(=O)c1 +CC(O)CCC(=O)N1CCC(Cc2ccccc2)CC1 +Cc1oncc1C(=O)N1CCC2(CC1)CCN(c1ccsc1)C2=O +CC1CN(c2ncc(-c3ccccc3)cn2)CC(C)O1 +COc1ccc2c(c1)cc(C(=O)NCCOc1ccccc1)n2C +Cc1ccsc1CNC(=O)Cn1c(C)nc(C#N)c1C#N +CN1C(=O)c2cc(Cl)ccc2NC1c1cnn(-c2ccccc2)c1 +CCC1CCCN(C(=O)c2[nH]c(C)c(C(=O)OCCOC)c2C)C1 +CCOC(=O)N1CCN(C(=O)c2cnc(N(C)C)nc2C)CC1 +CCSc1ccccc1C(=O)N1CCN(c2nccn2CC)CC1 +N#Cc1ccccc1COc1cccc(C(=O)N2CCC2)c1 +CC(=O)c1ccc2c(c1)NCC(c1ccccc1)O2 +CCC1=C(C(=O)OC)C(c2cnn(C)c2C)n2ncnc2N1 +CS(=O)(=O)N1CCCc2cc(NC(=O)c3cccs3)ccc21 +O=C(Nc1cccc2[nH]ccc12)N1CCN(C(=O)c2ccco2)CC1 +CCCN(CC(=O)OCC)C(=O)c1cccc2ccccc12 +O=C1CN(C(=O)NCCC(=O)NC2CC2)c2ccccc2N1 +CCOC(=O)c1cnn(C2CCCN(C(=O)c3occc3C)C2)c1 +O=C(NCc1cccc(N2CCCC2=O)c1)Nc1nccs1 +NC(=O)COC(=O)CCc1ncc(-c2ccccc2Cl)o1 +CC(Cn1cncn1)NC(=O)Cc1ccc(Cl)c(Cl)c1 +CN(Cc1ccccn1)C(=O)Nc1cccc(COCC2CC2)c1 +Cc1ccc(NC(=O)N2CCCCC2CO)cc1Cl +CSc1cc(C(=O)Nc2ccc(C(=O)NC(C)C)cc2C)ccn1 +Cc1noc(CNC(=O)C2CN(C(=O)c3cccs3)C2)n1 +CC(=O)N1CCCc2cc(S(=O)(=O)N=c3[nH]cccc3C)ccc21 +CCN(CC(=O)NC)C(=O)Cn1c(C(F)(F)F)nc2ccccc21 +COC(=O)NCC(=O)N1CCC(c2nc3ccc(F)cc3[nH]2)CC1 +CC(C)CCC(=O)N1CCN(CC(=O)N(C(C)C)C(C)C)CC1 +CC(=O)Nc1cccc(NC(=O)Nc2nonc2C)c1 +Cc1cc2c(s1)c1cnn(CCc3ccccc3)c(=O)c1n2C +N#Cc1ccc2c(c1)nc1[nH]c(Nc3ccccc3F)nn12 +COc1cccc2cc(C(=O)Nc3ccccc3-n3cnnn3)oc12 +COCCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(F)cc1 +CN(CCC#N)S(=O)(=O)c1ccc2c(c1)CCN2C(=O)C1CC1 +COc1cc2c(cc1OC)N1C(=O)c3ccccc3C1(O)OC2=O +Cc1cc(C)n(-c2ccc(NC(=O)N(C)CCC(C)O)cc2F)n1 +COC(=O)CCNC(=O)C1(c2cccc(Cl)c2)CC1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)C1CC(=O)N(C)C1 +c1ccc(CC2C(OCC3CC3)CCN2Cc2ccoc2)cc1 +CC(C)(CO)N(CCO)C(=O)c1ccc2c(c1)OCO2 +Cc1cnc(Oc2ccccc2CN2CCOCC2)c(Cl)c1 +COc1ccc2c(C(=O)N(C)Cc3cn(C)nc3C)cc(=O)oc2c1 +CCc1cnc(N2CCC3C2CCN3C(=O)c2cnn(C)c2)nc1 +O=C1CC(C(=O)N2CCCC2Cn2cccn2)CN1C1CC1 +CC(=O)Nc1c(-c2ccc(C)cc2)nc2scnn12 +COc1ccc(CC(=O)N2CCOc3ccc(F)cc32)cc1OC +O=C(NCC(O)c1ccc(F)c(F)c1)Nc1ccc2[nH]ncc2c1 +Cc1ccccc1COc1cccc(NCc2ncnn2C)c1 +CNC(=O)c1cc(C)ccc1NC(=O)COCc1nc(C)no1 +COC(=O)c1ccc(NCC(=O)Nc2ccc3c(c2)OCO3)c(C)c1 +CCSc1cccc(C(=O)Nc2nnc(-c3ccn(C)n3)o2)c1 +CCn1c(Sc2nccc(OC)n2)nnc1-c1ccc(OC)cc1 +CN1CC2CCC(CC1=O)N2C(=O)c1scc2c1OCCO2 +CC(=O)c1ccc(NC(=O)CN2CCSc3ccccc32)cc1 +CCCCC(NC(N)=O)C(=O)N1CCCC2CCCCC21 +Cc1ocnc1C(=O)Nc1ccc(C(=O)OC(C)(C)C)cc1F +CC(C)n1c(C2CCCN(C(=O)c3cnccn3)C2)nc2ccccc21 +CS(=O)(=O)Nc1ccccc1NC(=O)c1ccc2ccccc2c1 +Cc1ccc(C(C)NC(=O)CCNC(=O)C2CC2C)s1 +Cc1cc(C)c2c(N)c(C(=O)N3CCCC3)sc2n1 +Cc1cc(C)c(C(=O)OCCc2ccccc2F)c(=O)[nH]1 +CCCC1CN(C(=O)CC2=CCCCC2)CCO1 +CC(c1nc(-c2cccnc2)no1)N1CCc2ccc(Cl)cc2C1 +O=C(C1CNCc2ccccc21)N1CCc2ccccc2C1 +O=C(NCCc1cscn1)c1cc(F)cc(C(F)(F)F)c1 +CCCCC(=O)Nc1cc(OC)c(OC)cc1C(N)=O +CC(=O)N(Cc1ccccn1)c1ccc(Cl)cc1 +COc1ccc(NC(=O)N2CCN(CC3CCCO3)CC2)cc1F +CCOc1ccc(C(=O)N2CCN(c3ncccn3)CC2)cc1OC +O=C(Nc1ccc(F)c(F)c1F)c1ccc(F)c(F)c1 +COCc1ccc(C(=O)N(C)Cc2ccc(C(F)(F)F)cc2)o1 +O=C(CNC(=O)c1c[nH]c2ccccc12)Nc1cccnc1 +CCC(=O)N1CCC(NC(=O)c2ccccc2)CC1 +CNc1ncc(Br)cc1C(=O)NCc1scnc1C +O=C(Nc1cc(-c2ccncc2)n[nH]1)c1cccs1 +COc1ccc(C(=O)Nc2c(C)cc(O)cc2C)cc1 +CCOCc1ccccc1CNC(=O)NC(C)c1c(C)noc1C +CCn1cc(NC(=O)NC2Cc3ccccc3C2)ccc1=O +CC(C)C(=O)Nc1ccc(SCc2ccccn2)nn1 +CC(C)(C)c1ccc(C(=O)NCC(=O)N2CCNCC2)cc1 +O=C(Oc1cc(Cl)cc(Cl)c1)C1CCOCC1 +CCC(C)(S(=O)(=O)c1ccccc1)S(=O)(=O)c1ccccc1 +COC1C2=C(CCCC2)C(=O)N1CCCOC(C)C +COC(=O)C1CCCc2nc(-c3ccc(-n4ccnc4)cc3)nn21 +O=C(Cc1ccc(F)cc1)N(Cc1ccoc1)Cc1cccs1 +Cc1oc(C(=O)OC2(C3CC3)CC2)cc1S(=O)(=O)N(C)C +CC(=O)Nc1ccc(NC(=O)c2cnccn2)cc1C +Cn1ccnc1Sc1ccc(Cl)cc1NC(=O)Cn1cccn1 +O=C(Cn1ncc(-c2ccc(Cl)cc2)nc1=O)Nc1ccccc1 +O=C(Nc1cccc(Nc2ccccc2)c1)c1cnccn1 +CN(Cc1cnc2cnccn12)C(c1ccccc1)C(F)(F)F +CC(=O)NCC(=O)NCC(=O)N1CC(c2ccc(F)cc2)CC1C +Cc1cccc(S(=O)(=O)CC(=O)N(Cc2ccccc2)C2CC2)c1 +CCOc1cccc(CNC(=O)c2ccc3c(c2)CC(=O)N3C)c1 +CCCn1cc(NC(=O)NCc2ccc(OC)cc2OC)nn1 +CCn1c(SCC(=O)NCc2cnc(C)s2)nc2ccccc21 +CNC(=O)C1CN(CC(=O)Nc2cccc(C)c2)c2ccccc2O1 +CC(Oc1ccccc1)C(=O)NCCc1nnc2n1CCC2 +Cc1oc(N)c(C(=O)C(C)(C)c2ccccc2)c1C(N)=O +O=c1c(=O)n2c(nn1Cc1ccccc1F)N(c1ccccc1)CC2 +COc1cc2[nH]c(=O)n(Cc3cccnc3)c(=O)c2cc1OC +CCc1c(C(=O)OC(C)c2nc(C)no2)cnn1-c1ccc(C)cc1 +CCC(=O)N1CCCN(c2ccc(C#N)cc2)CC1 +CC(NC(N)=O)C(=O)NC(C#N)c1ccc(Cl)c(Cl)c1 +Cc1nc(CC(=O)Nc2ccc(NC(=O)C3CC3)nc2)cs1 +O=C(c1cccs1)N1CCN(Cc2ccsc2)CC1 +O=C(NCC1CCCCC1)c1cn[nH]c1-c1cccs1 +CCOC(=O)c1nsc(C(=O)NCc2ccccc2)c1N +CN(C(=O)c1cnc2c(c1)NC(=O)CS2)C1CCCCC1 +O=C(NCc1ncc[nH]1)Nc1ccccc1OC1CCOC1 +COc1ccc(NC(=O)c2cc(Cl)ccn2)c(OC)c1 +CCC(C)n1nccc1NC(=O)c1ccc2c(c1)CCC(=O)N2 +COC(=O)c1ccc(Cn2c(=O)c(=O)n(C)c3cccnc32)cc1 +CCc1cccc(NC(=O)NC(C(=O)OC)C(C)C)c1 +Cc1ccc2oc(C(=O)NCc3nc4ccccc4[nH]3)cc(=O)c2c1 +CC(=O)c1cc2c(Br)cccc2oc1=O +COc1cccn(CC(=O)N(CC2CCC2)CC2CCCO2)c1=O +CCN(CC)C(=O)N1CCC(C(=O)NC(C)(C)C(=O)OC)CC1 +CCOc1ccc(C(O)C2=CCCC2)cc1OCC +O=C(NCc1ccc(F)cc1)c1cn2cc(Cl)ccc2n1 +COC(=O)C(NC(=O)c1cccc(C)n1)c1ccc(Cl)c(F)c1 +CCCCn1nccc1NC(=O)c1cc(=O)[nH]c2ccccc12 +CCN(CC(O)c1ccc(C)cc1)C(=O)c1cc(C)cc(F)c1 +O=C(COC(=O)c1ccc2ccccc2c1O)NCC(F)(F)F +O=C(NCc1cccnc1-n1cccn1)N1CCC1c1ccccc1 +COCCOc1cccc(NCc2cnn(C)c2)c1 +CCCS(=O)(=O)N1CCC(Cc2ccccc2)CC1 +O=c1ccc2ccc(OCCn3c(=O)oc4ccccc43)cc2o1 +CCN(CC)c1ccc(C(=O)Nc2nc3ccc(F)cn3n2)cn1 +Cc1cc(Cl)cc(C)c1CN1CCCC(c2nncn2C)C1 +CN(C)c1ccc(C(=O)OCC(=O)N2CCOCC2)cc1 +CC1CCCCN1C(=O)c1snc(C#N)c1N +CCCNS(=O)(=O)c1ccc2c(c1)N(C)C(=O)C(C(C)C)O2 +O=C(Nc1ccccc1)Nc1ccccc1C(=O)NCc1ccco1 +O=c1c(Cl)c(Cl)cnn1Cc1ccc(-n2cccn2)cc1 +C=CCn1c(CCCNC(=O)C2CC2)nc2ccccc21 +c1ccc2nc(N3CCCC3)c(NC3CCOCC3)nc2c1 +CC(C)(C)NC(=O)c1c(F)cccc1C(F)(F)F +CCS(=O)(=O)NCCNC(=O)C1(c2ccccc2)CC1 +C=CCc1cc(C(=O)N(C)c2ccccn2)cc(OC)c1OC +CC(=O)c1cc(F)ccc1N(C)Cc1ccccn1 +CCn1nnnc1-c1cccc(C(=O)Nc2ccc(C)cn2)c1 +CCN(CC)C(=O)CCCNC(=O)Nc1nncs1 +O=C(NCCNC(=O)c1cnc2cc[nH]c2c1)Nc1ccccc1 +Cc1nc(C)c(CNCc2ccc(F)c(C)c2)s1 +Cc1cc(NC(=O)C2COc3ccccc3C2)n(C)n1 +CN(Cc1cc(C(C)(C)C)n[nH]1)Cc1ccccc1C#N +CCOc1ccc(C(=O)NCC(=O)N(C)C)cc1OCC +O=C(Nc1cncnc1N1CCCC1)c1ccn(C2CCCC2)n1 +CCOC(=O)c1nn(CC)c2c1CN(C(=O)c1nonc1C)CC2 +O=C(c1cnccn1)N1CCCC2(CCN(c3ccccc3)CC2)C1 +O=C(Nc1cccn2nc(C3CCC3)nc12)c1c(F)cccc1Cl +Cc1n[nH]c(SCC(=O)NCC2CCCO2)n1 +CS(=O)(=O)N1CCC(c2nc(CCCc3ccccc3)no2)CC1 +CN(C)C(=O)Cc1ccccc1NC(=O)NC1CCCC1 +CCCCOc1c(Cl)cc(C(=O)N2CCNC(=O)C2)cc1OC +CCn1c(C)cc(C(=O)N2CCc3ccccc32)c1C +CCc1onc(C)c1NC(=O)CCc1ccncc1 +CCOC(=O)C(O)(c1ccc(Cl)cc1)C(F)(F)F +COC(=O)CNC(=O)c1cnc(SC)n1-c1ccccc1 +O=C(c1cccnc1)N1CC2(CCN(C(=O)c3cscn3)C2)C1 +CCNC(=O)N1CCN(C(=O)Cc2cccc3ccccc23)CC1 +Nc1cc(CCC(=O)N2CCCc3ccccc32)ccc1O +COc1ccc(C(=O)NCCC(=O)Nc2ccc(C)cn2)c(O)c1 +CCc1ccc2c(Cn3cc(C(=O)NC)ccc3=O)cc(=O)oc2c1 +CCn1cc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)cn1 +Cc1cnc(CNc2c(C#N)nnc3ccccc23)o1 +CCC(C)C(=O)NCCCc1nn(-c2ccccc2)c(N)c1C#N +CN(C)c1ccnc(Nc2ccc(F)cc2F)c1C#N +COCC(=O)Nc1ccc(Oc2ccc(C)cc2OC)c(F)c1 +Cc1ncc(C(=O)N2CCC(Nc3cccnn3)CC2)s1 +O=C(NCc1nnc2ccccn12)NC1Cc2ccccc2C1 +COc1cc2nc(C)sc2cc1NC(=O)c1cnn(C)c1 +CC1=C(C=C2OC(=O)c3c2cc(C)[nH]c3=O)C(C)C(C#N)=N1 +CC(C)n1c(=O)c(NCCc2ccc(Cl)cc2)nc2ccncc21 +N#CC1CN(Cc2ccccc2)c2ncc(-c3ccccc3)nc21 +Clc1ccccc1-n1cc(NCc2cc[nH]n2)cn1 +COc1ccc(-c2nnc(SCC(=O)N3CCCCC3)n2C)cc1 +NC(=O)C1Cc2ccccc2N(Cc2nc(Cc3ccccc3)no2)C1 +O=S(=O)(Nc1cccc(-c2cn[nH]c2)c1)c1ccccc1 +Cc1ccc(Cl)cc1S(=O)(=O)Nc1ccccn1 +CC1=C(C(=O)N(C)C)C(c2ccccc2Cl)NC(=O)N1 +Cc1c(C(=O)NC(C)C)nc2ccc(Cl)cn12 +CC(C)CCCC1CN(C(=O)CCc2cn[nH]c2)CCO1 +c1ccc2c(NCc3nnc(C4CCC4)o3)cccc2c1 +CCC(CC)c1cc(CNS(=O)(=O)c2c[nH]c3ncccc23)on1 +CC(NC(=O)c1ccc(=O)n(C)n1)c1nnnn1-c1ccccc1 +O=C(CN1CCCCC1=O)NCCSc1ccc(Cl)cc1 +Cc1cc(C)c(NC(=O)CN(C)C(=O)c2ccccc2)c(C)c1 +O=C(CN1C(=O)c2ccccc2S1(=O)=O)Nc1ccccc1 +COc1ccccc1NC(=O)c1ccc(Cn2cncn2)cc1 +Cc1ccc(C(=O)NC2CCN(C(=O)Nc3cn[nH]c3)CC2)o1 +CCOC(=O)c1c(C(=O)N2CCCCC2)n[nH]c1Nc1ccccc1 +CCN(CC(C)C#N)C(=O)c1ccc(F)cc1F +Cn1c(C(=O)NCC(=O)NCc2ccncc2)cc2occc21 +CCc1ccc(NC(=O)CSc2nnnn2-c2cccnc2)cc1 +N#Cc1ccc(NC(=O)c2cc3ccccn3n2)cc1 +CCOC(=O)Cn1c(=O)c2ccccc2n(CC)c1=O +CC(C1CC1)n1nccc1NC(=O)CSc1n[nH]c(N)n1 +CC(C)NS(=O)(=O)c1ccc2c(c1)NC(=O)C(C)N2 +O=C1N(Cc2ccccc2)c2ccc(Cl)cc2C12OCCCO2 +CCOC(=O)CN(C)S(=O)(=O)c1ccc(C)cc1C +CCC(=O)Nc1ccc(C(=O)NCCCOC)cc1 +CC(COc1ccc(F)cc1)NC(=O)Nc1cn[nH]c1 +CNC(=O)CSc1nc(N)c(NC(=O)c2ccccc2)c(=O)[nH]1 +NC(=O)c1cccc(NC(=O)c2cc(-c3cccc(Cl)c3)[nH]n2)c1 +Cc1ncsc1C(=O)N(CC(C)C)CC(F)(F)F +O=C(NCC(O)C(F)(F)F)Nc1ccccc1F +Cc1ccc(-n2ccnc2)c(C(=O)N(C)CCOc2ccccc2)c1 +CCn1nccc1C(=O)NC(C)c1ccc(OC)cc1 +Cc1ccc2ccc(S(=O)(=O)N3CCOCC3)cc2c1 +CC(CN1CCCC1=O)Nc1cnc2ccccc2n1 +COc1ccc(-n2nnc(C#N)c2-c2ccccc2)cc1 +CCc1csc(CNC(=O)CC2NC(=O)c3ccccc32)n1 +CN1C(=O)CC(Sc2ccccc2)c2ccccc21 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)C1CC1c1ccccc1 +Cc1cccc(C(=O)Nc2cc(Cl)ccc2Cl)n1 +CCC(=O)Nc1ccc(C)c(NC(=O)NCc2ccnn2C)c1 +Cn1cc(S(=O)(=O)Oc2ccc(CC#N)cc2)cc1C(N)=O +COc1ccc(-c2c3c(=O)n(C4CC4)ccc3nc3ncnn23)cc1 +CC(=O)Oc1ccc2c(=O)c(Oc3ccc(F)cc3)coc2c1 +Cc1cc(C)c(CNC(=O)C2(c3ccccc3)CC2)c(=O)[nH]1 +O=C(c1ccc(-c2ccccc2)cc1)N1CCN=C1c1ccccc1 +N#Cc1ccc(Cl)cc1Sc1nc(N)cc(N)n1 +COc1ccc(NC(=O)COc2cccc(Br)c2)cn1 +Cc1csc(-c2cccc(C(=O)OCC(N)=O)c2)n1 +O=C(Nc1cccc2[nH]cnc12)c1c[nH]nc1-c1ccccc1F +CN1CCC2(CCN(C(=O)c3ccncc3)CC2)C1=O +COc1cccc(C(=O)Nc2nc(C)c(SCC#N)s2)c1F +CC(=O)N1CCCN(CCn2cncn2)c2ccccc21 +N#Cc1ccc(OCC(=O)N2CCNC(=O)C2)c(Cl)c1 +CCOc1ccc(C(=O)CN2CCOCC2)c(OCC)c1 +O=C(CCc1ncc(-c2ccccc2Cl)o1)NCc1ccncc1 +Cc1ncc(CNC(=O)NCCc2c(F)cccc2F)s1 +CC1CCCCC1NC(=O)c1ccc(N)c(OCC#N)c1 +CCC(Sc1ccccc1)C(=O)Nc1nc(C)ncc1C#N +CC(C)c1ccc(O)c(C(=O)Nc2cnn(CC(N)=O)c2)c1 +CC(=O)NC(C(=O)NCCCc1cn[nH]c1C)C(C)C +C=C(C)CN(CC)C(=O)Nc1ccc(Oc2cccnc2)nc1 +O=C(NCc1ncc[nH]1)c1ccc(-n2ccnn2)cc1 +COc1ccc(OCCCn2nnc(CO)c2C)cc1 +CC1CN(c2nc3c(s2)C(=O)CCC3)CCCO1 +Cn1cc(NC(=O)c2cc(N)ccc2Cl)cn1 +Cn1cc(C(C)(O)CNC(=O)Nc2cccc(C(F)F)c2)cn1 +C#Cc1cccc(NC(=O)CNC(=O)c2ccc(OC)nn2)c1 +COc1ccc(C2c3c(nc[nH]c3=O)Oc3nc[nH]c(=O)c32)cc1 +COc1ccc(-c2nc(COc3cccc4c3CCC4=O)no2)cc1 +O=C1CC(c2ccccc2Cl)c2cnn(-c3ccccc3)c2N1 +O=C(C1CCCCC1)N1CCn2nc(-c3ccccc3)nc2C1 +Cc1nn(CCC#N)c(C)c1CCC(=O)N1CCOC2CCCC21 +O=C(c1ccc(-n2cccn2)c(F)c1)N1CCOCC1C1CC1 +CC(=O)Nc1ccc(NC(=O)c2cc(Br)c[nH]2)cc1 +CC(C)c1nc(CSc2ccccc2)sc1CO +Cc1ccc(C(C)NC(=O)CNS(=O)(=O)c2cnn(C)c2)cc1 +Cc1ncoc1C(=O)NC(c1ccccc1)c1ccccc1 +CC1(C)Cc2cccc(CNc3ccc4[nH]nc(C(N)=O)c4c3)c2O1 +CCNC(=O)c1ccc(NS(=O)(=O)c2ccccc2OC)c(C)c1 +O=C(Cc1c[nH]c2ccccc12)Nc1cccc(N2CCOC2=O)c1 +N#Cc1ccc(F)c(C2NCCc3cc(F)c(O)cc32)c1 +Nc1ccc2oc(-c3ccc(F)c(F)c3F)nc2c1 +CCN(CC1COc2ccccc2O1)C(=O)c1cc2ccccc2[nH]1 +NS(=O)(=O)CCNC(=O)c1csc(-c2ccccc2Cl)n1 +O=C(NCc1cccs1)c1noc2ncnc(N3CCOCC3)c12 +CNC(=O)C1CCCN1C(=O)Nc1ccccc1C +CC(C)CC(=O)N(C)C(C#N)c1ccc(Cl)cc1 +CCNS(=O)(=O)c1ccc(C(=O)N(C)c2nccs2)cc1 +CCS(=O)(=O)N1CCN(c2ccc(-n3ccc(C)n3)nn2)CC1 +Fc1ccccc1N1CCN(c2c3c(nc4nncn24)CCC3)CC1 +CCC(CO)NS(=O)(=O)c1cc(C)c(C)cc1N +Cc1nn(C)c(C)c1C(=O)Nc1ccc(Cl)c(Cl)c1 +CC(C)Cc1nnc(NC(=O)NC2CCCC2)s1 +NC(=O)c1cccc(CCNCc2cc(F)ccc2F)c1 +COCCNC(=O)c1ccc(C)c(Br)c1 +NC(=O)C(Cc1ccccc1)NC(=O)c1cccc(Cn2cccn2)c1 +CNC(=O)c1cc(S(=O)(=O)Nc2ccccc2)ccc1OC +CC(C)CC(O)CNC(=O)c1ccc(-n2cnc3ccccc32)nc1 +CC(c1ccc2ccccc2c1)N(C(=O)CCCn1cncn1)C1CC1 +COc1cc(C)c(C(=O)NC(C#N)c2ccccc2OC)cc1OC +CC(C)Oc1cccc(C(=O)N(CCC#N)Cc2ccccc2)c1 +O=C(CSc1nnc(-c2ccco2)o1)c1ccc(Cl)cc1 +Cc1cc2nc(CCO)n(CC(=O)N(C(C)C)C(C)C)c2cc1C +COc1c(F)ccc2c1CCNC2c1ccncc1 +Cc1cc(C(=O)Nc2c(F)cccc2F)c2cnn(C(C)C)c2n1 +Cc1ncsc1CCN(C)c1nccc(-c2ccncc2)n1 +O=C1CN(C(=O)Cc2coc3cc4c(cc23)CCC4)c2ccccc2N1 +CC(CO)NC(=O)C1(c2cccc(Cl)c2)CC1 +CCc1c(C(=O)OCC(=O)N2CCOCC2)cnn1-c1ccccc1 +CCn1c(=O)[nH]c(=O)c2c(C(=O)OC)cc(-c3ccc(C)cc3)nc21 +Cc1ccccc1CN1C(=O)C(=O)c2cc(F)ccc21 +CCCn1nnnc1COc1cccc(-n2cnnn2)c1 +CC(Sc1ccccc1)C(=O)OCC1CCCCO1 +Cc1ccc(S(=O)(=O)N2CCN(C(C)(C)C#N)CC2)s1 +O=C(Nc1ccc(F)c(F)c1)c1ccncc1F +CS(=O)(=O)Nc1c(O)cccc1OC1CCCCC1 +COc1ccc(C2CCN(C(=O)C3CC=CC3)C2)cc1 +CNC(=O)c1ccc(NC(=O)CNc2ccc(F)c(Cl)c2)cc1 +Nc1cc(F)ccc1C1NCCc2c(F)cc(O)cc21 +COCC(C)NS(=O)(=O)Cc1ccc(Cl)cc1 +CC(C)(C(N)=O)S(=O)(=O)c1ccc(Br)cc1 +CCn1c(-c2cccc(OCC(C)C)c2)ccc(CO)c1=O +Cc1nc2cccc(F)c2n1Cc1cccnc1N +CCC1(NC(=O)NCc2ccnc(OC3CCC3)c2)CCC1 +O=C(NCc1ccnc(OCC(F)(F)F)c1)N1CCC(CO)CC1 +CN(Cc1ccc(O)cc1)C(=O)c1c[nH]nc1-c1ccc(Cl)cc1 +O=C(NCc1cc(Br)c2c(c1)OCO2)c1ccccn1 +O=C(NC(c1nnn(CC(F)(F)F)n1)C1CC1)c1ccccc1 +COCCNC(=O)NCc1cccnc1OC1CCCC1 +Cc1cccc(Oc2ccccc2NC(=O)N(C)CCC#N)c1 +CC(C)C1C(=O)NCCN1Cc1cnc2cnccn12 +Nc1ccc2c(c1)N(C(=O)Cc1noc3ccccc13)CC2 +Cc1ccc(S(=O)(=O)CCOC2CCCCC2C)nc1 +O=C(Nc1nncs1)c1cnn(-c2ccccc2)n1 +Cc1ccccc1C(=O)N1CCCC(CNC(=O)C(C)C)C1 +O=C(CN1CCN(c2ccc(F)cc2)CC1)c1ccc2cc[nH]c2c1 +COCc1cc(=O)[nH]c(Nc2ccc(C(F)(F)F)cc2)n1 +Cc1nc2ccc(NC(=O)C3CCCN3C(=O)C(C)C)cc2o1 +C=CCN(Cc1ccc(C#N)cc1)C(=O)NCCN1CCOCC1 +COc1cccc(COC(C)c2nc(C(C)(C)NC(C)=O)no2)c1 +O=C(Nc1ccc2c(c1)CCC2)c1ccn2nccc2c1 +COc1ccccc1C(=O)N1CCCC(c2n[nH]c3nccnc23)C1 +Cc1nc2cc(NC(=O)CCc3c(C)nn(C)c3C)ccc2o1 +COc1ccc(CCC(=O)Oc2ccc3cn[nH]c3c2)cc1OC +CCCCNC(=O)Nc1ccc(S(=O)(=O)CC2CCCO2)cc1 +O=C(NC1CCOC1c1ccc(F)c(F)c1)c1cccc2cn[nH]c12 +CCOCCNC(=O)N1CCC(c2nc3ccccc3[nH]2)CC1 +Cc1cccn2c(=O)c3c(nc12)CCN(C(=O)NC(C)(C)C)C3 +CC(C)OCCCNC(=O)c1cc(Br)ccc1F +COC(=O)CNC(=O)CNS(=O)(=O)c1cn[nH]c1 +CN(Cc1cccnc1)Cc1c[nH]nc1-c1ccc2c(c1)OCO2 +CN(C(=O)CSc1nnc(-c2ccncc2)n1C1CC1)C1CC1 +O=C(c1ccccn1)N(CCc1ccccc1)C1CCOC1 +COc1ccc(C(=O)Nc2cccc(OC)c2)cc1 +Cc1c(Cl)cnc(NC(=O)CSc2nncn2N)c1Cl +Cc1cnc(NC(=O)CCSc2ccccc2F)s1 +CC(C)c1n[nH]c(SC(C(=O)N2CCOCC2)c2ccccc2)n1 +CCOc1ccc(OCC)c(NC(=O)c2cccc(NC(C)=O)c2)c1 +O=C(COC(=O)c1cccc(F)c1)Nc1ccc2c(c1)OCO2 +Cc1cc(C)n(CCCNC(=O)Nc2cnccc2C)n1 +CN(CC1(CO)CCC1)C(=O)C1CCCN1C(=O)C1CCCCC1 +COc1cccc(NC(=O)CSc2nc(C)c(CCO)c(=O)[nH]2)c1 +Cc1noc(CCCC(=O)NC(c2nc3ccccc3[nH]2)C(C)C)n1 +CCOC(=O)CN(C(=O)c1ccc(N(C)C)nc1)C(C)C +COC(=O)C1CCCN1C(=O)C(N)c1ccccc1 +O=C1CCCN1c1ccc(-c2csc(C3CC3)n2)cc1 +NS(=O)(=O)c1ccc(CCNc2ccc3nnnn3n2)cc1 +CCn1c(SCC(=O)N2CCOCC2)nnc1-c1cccs1 +CC(=O)c1sc(NC(=O)c2cccc(C)c2)nc1C +Cc1ccc(NC(=O)Cn2ncc3c2c(C)nn3C)nc1 +OC(CCN1CCOCC1)C1c2ccccc2Cc2ccccc21 +Cc1ccc(N2C(=O)CCC2(C#N)c2ccccc2)cc1 +COc1ccc(NC(=O)NCc2ccnc(OC(C)(C)C)c2)cc1F +CC1(C(=O)NC2C3CCOC3C2(C)C)Cc2ccccc2C(=O)O1 +Cc1cc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)on1 +COc1cc(C)c(C(=O)NC2CC(C)(OC)C2(C)C)cc1OC +Cc1cccc(C(=O)Nc2nc(-c3ccccn3)cs2)c1C +C=CCc1cc(C(=O)NCC(N)=O)cc(OC)c1OC +NS(=O)(=O)c1ccc(CNCc2ccccc2C(F)(F)F)cc1 +Cc1nc(C2CCCN(c3cnccn3)C2)ncc1C(N)=O +Cc1nc(C(=O)N2CCCC2c2noc(C3CC3)n2)ccc1C#N +Nc1nc(N)nc(COc2ccc3ncccc3c2)n1 +CCCNC(=O)COc1cccc(C(=O)OC)c1 +Cc1nc2cc(C3CCCCN3C(=O)C3CC3)nn2c(O)c1C +CC(C)(C)NC(=O)CNC(=O)NCc1cccc(Cn2cccn2)c1 +CCN(CC)S(=O)(=O)N1CCCC1c1ccc[nH]1 +Cc1c(C(=O)N2CCCCC2)sc2nc[nH]c(=O)c12 +CCCNC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1O +Cc1oc(-c2cccc(Cl)c2)nc1Cn1cccn1 +Cc1c(CNc2nnc(CC(C)(C)C)o2)cnn1C +COC(=O)c1cc(NC(=O)Cc2noc3ccccc23)c(F)cc1F +COc1ccc(NC(=O)NC(c2nccn2C)C(C)C)cc1Cl +Cc1cc(NC(=O)NCc2nncn2C)c2ncccc2c1 +Cc1cc(C(=O)Nc2ccc(OC(C)C)cc2)[nH]n1 +CNS(=O)(=O)c1cccc(C(=O)N2CCCC2c2cnn(C)c2)c1 +O=C(Cc1ccc(-n2cnnn2)cc1)NCCc1cc2ccccc2o1 +CCCCn1c(N)c(N(CC)C(=O)CC(C)(C)C)c(=O)[nH]c1=O +Clc1ccc(CCc2nc(C3CCOC3)no2)cc1 +COc1ccc(Nc2c(C#N)cnc3ccc(F)cc23)c(OC)c1 +COC(=O)CC1CCN(C(=O)c2csc(-n3cccc3)n2)CC1 +O=C(Nc1onc2c1CCCC2)c1ccccc1Cl +CC(C)Cc1nc(NC(=O)CCc2ncc(-c3ccccc3)o2)n[nH]1 +O=C(Nc1ccc(F)cc1OCC(F)(F)F)C1CC1 +CCn1cnnc1CNC(=O)c1cc(Cl)cc(Cl)c1 +CC1=NC(=O)C(NC(=O)c2cccc(Cl)c2)(C(F)(F)F)C1C#N +CCC(CC)NC(=O)NCCNC(=O)c1ccoc1 +CN(C)S(=O)(=O)c1ccc(OCc2noc(C3CC3)n2)cc1 +CC1CCN(C(=O)CSc2nc(=O)[nH]c3c2CCC3)CC1 +O=S(=O)(Cc1ccccc1)N1CCC2(CC1)OCc1ccccc12 +Cc1ccc(CN2CC3OCCN(C(C)C)C3C2)o1 +Cc1ccc(-c2ccnc(NC(C(N)=O)C(C)O)n2)c(C)n1 +COc1ncccc1CNC(=O)c1cnc(C)cn1 +CCCOCC(=O)Nc1cc(C(=O)N2CC(C)CC(C)C2)ccc1C +Cc1cc(Br)ccc1NC(=O)CNC(=O)c1ccccc1 +COCc1ccc(C(=O)N2CCCC2c2nnc3ccccn23)cc1 +Cc1ccccc1-c1cncc(C(=O)NCC(C)C)c1 +COC(=O)C1CN(c2cccc(C)c2C)CCC1=O +Nc1ccccc1NC(=O)Cn1ncc2ccccc2c1=O +CCC(NC(=O)c1cnc(C(C)(C)C)s1)c1ccncc1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(Cl)ccc2F)c1C +Nc1nccc(C2CCCN2C(=O)c2cnco2)n1 +CC(C)N1CC(C(=O)Nc2ccc(-n3cc(Cl)cn3)nc2)CC1=O +COC(=O)c1ccc(C(=O)N(Cc2cccc(F)c2)C2CC2)nc1 +CC(C)(CNc1nc(-c2cccnc2)nc2ccccc12)C(N)=O +COC(=O)Cn1c(CNC(=O)c2cccnc2)nc2ccccc21 +CC1Nc2cc(Br)ccc2N(CCC#N)C1=O +CN(CCCc1ccccc1)S(=O)(=O)N1CCCC1 +CCOc1ccc(NC(=O)c2nn3cccnc3c2Cl)cc1 +Cc1ccc(S(=O)(=O)NCC(O)C2CCCCC2)cc1C +COc1ccc(CN(C)S(=O)(=O)c2ccccc2F)cc1 +COC(=O)CNC(c1c(F)cccc1F)C(F)(F)F +CCOc1cc(Cl)cc(F)c1-n1nc(C#N)cc1N +O=C(Nc1cccc(F)c1)c1cc(F)ccc1-n1cnnn1 +CCOCC1CCCN(S(=O)(=O)c2ccc(F)c(C)c2)C1 +Cc1ccc(-n2nnc(-c3noc(-c4ccc[nH]4)n3)c2C)cc1 +Cc1nc(C)n(CC(=O)NCc2ccc(C(=O)N3CCCC3)cc2)n1 +CC(C)c1nnc2sc(-c3ccc(F)cc3F)nn12 +CNC(=O)NC(C)c1cccc(NS(C)(=O)=O)c1 +CC(=O)Nc1cc(S(=O)(=O)Oc2ccccc2C#N)ccc1F +Cc1ccccc1C(C)(C)CNC(=O)CNC(=O)c1ccoc1C +Cc1cnn(C2CCCN(C(=O)c3cc(C)n(C4CC4)c3C)C2)c1 +CC(C)c1nnnn1CC(=O)Nc1ccn(-c2ncccc2Cl)n1 +O=C(Nc1cc[nH]n1)C1CCCC(C(F)(F)F)C1 +Cc1nnc(N2CCC3(CC2)COC(COc2cccnc2)C3)s1 +Cc1ccc(CNC(=O)Cc2c[nH]c3ncccc23)cc1C +CCc1nn(C)c(CC)c1CNC(=O)NC(C)c1nnc2n1CCC2 +O=S(=O)(c1cccnc1)N1CC2CC3CC(C2)CC1C3 +CC1Oc2ccccc2N(CC(=O)Nc2nc3ncccn3n2)C1=O +CC(C)OCCC(=O)N(C1CC1)C1CCCc2ccccc21 +COc1ccc(-c2noc(COc3ccc(C)cn3)n2)c(OC)c1 +COc1ccc(OC)c(CC(=O)NCc2ccncc2)c1 +Cc1ccc2nnc(C(=O)NCc3ccccn3)cc2c1 +Cc1ccc(F)c2c1N(C(=O)CCc1c(C)nn(C)c1C)CCC2 +Cc1ncc(C(C)NCC(c2ccccc2)N2CCOCC2)c(C)n1 +Cc1cc(C(=O)N(C)Cc2nc3ccccc3c(=O)[nH]2)no1 +COC(=O)c1cccc2nc(-c3ccc(-n4ccnc4)cc3)nn12 +O=C(NCc1ccc2c(c1)OCO2)C1CCn2c(nc3ccccc32)C1 +COC(=O)c1cccc(OCc2cccc(C(N)=O)c2)c1 +CCc1nc(CC(=O)Nc2ccc(-n3cncn3)c(F)c2)cs1 +CCSc1ccc(C(=O)Nc2ccc(OCC(=O)NC)cc2)cn1 +COC1CCCCCC1NC(=O)NC(C)CC(O)c1ccco1 +CCCCS(=O)(=O)Nc1cnn(Cc2c(F)cccc2Cl)c1 +CN(Cc1cc2ccccc2o1)C(=O)N=c1[nH]nc2ccccn12 +CCn1cnnc1CNC(=O)Cn1cc(C)c2ccccc21 +C=CCNS(=O)(=O)c1cc(C)c(Cl)cc1Cl +CC(OC(=O)c1cnc2c(cnn2Cc2ccccc2)c1)C(N)=O +Cn1cnc2c1c(=O)n(CCCOC(=O)c1ccccc1)c(=O)n2C +COc1ccc(NC(=O)c2cccs2)cc1-n1cnnn1 +Cc1ccccc1C1=Nn2c(nnc2-c2cccnc2)SC1 +Cc1ccc(CNC(=O)c2nc3nc(C)cc(C)n3n2)c(C)c1 +Cc1cc(C)c2nnc(C(=O)c3ccccc3)n2n1 +Cc1ccc(C)c2c(C)c(C(=O)Nc3ccccc3C(N)=O)oc12 +CN(C)c1nc(NCc2cccs2)ncc1F +NC(=O)c1ccc(Nc2cc(N)ccc2Cl)cc1 +O=C(Cc1ccc(O)cc1)NCc1ccnc(OC2CCC2)c1 +CC(C)(C)OC(=O)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +Cc1cccc(N2CCN(c3nnc(C(F)(F)F)s3)CC2)c1 +CN(Cc1ccccc1)C(=O)NCCC(=O)N1CCCC(O)C1 +Cc1nccn1-c1cc(CNC(=O)c2ccsc2)ccn1 +C=CCOc1c(CN2CCC3(C2)OCCO3)c(C)nn1C +N#Cc1ccc(C(=O)NCC2CCN(S(=O)(=O)C3CC3)CC2)cc1 +C=CCN(CC1CCCCC1)C(=O)NCCNC(C)=O +O=C(Cn1nnc(-c2ccc(Br)cc2)n1)c1ccccc1 +CC(C)CC(=O)Nc1nnc(CCc2ccccc2)s1 +CCOc1ncccc1C(=O)NC1CCN(S(C)(=O)=O)CC1 +CCC(=O)Nc1cccc(C(=O)N2CCC(C)CC2)c1 +COc1ccnc(N(C)CC(=O)Nc2ccc(C)cc2)n1 +Cc1ccc2cccc(NC(=O)c3cc4c(C)nn(C)c4s3)c2n1 +CC1CCCC1NC(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +Cc1nsc(NC(=O)N2CCCCC2c2cccc(F)c2)n1 +C=CCn1c(=O)c2ccccc2n(CC(=O)Nc2ccc(C)cc2)c1=O +CCc1ccc(NC(=O)c2cnn(-c3ccncc3)c2C)cc1 +CNC(=O)COC(=O)c1cccc(OCc2ccccc2)c1 +CCN1C(=O)CCCC12CCCN(C(=O)c1ccoc1)C2 +CCOc1ccc(NS(=O)(=O)c2cc(N)ccc2OC)cc1 +CCc1ccccc1NC(=O)CN(C)C(=O)CCc1ccco1 +OCC1(CSc2nnnn2C2CCCC2)COC1 +Cc1cc(C(=O)N2CCOC(c3ccccc3)C2)c(C)n1C1CC1 +Fc1ccc(C(CC(F)(F)F)NCc2ccccn2)cc1 +CC1CC=CCC1COC(=O)c1cnn2cccnc12 +CCCn1cc(C(=O)N2CCC3(C=Cc4ccccc43)CC2)c(C)n1 +NC(c1cccc(Oc2ccc(F)cc2)c1)C(F)(F)F +CN1CC(=O)N(c2ccccc2)CC12CCN(C(=O)C1CCC1)C2 +Cn1cc(CCNCc2cc(Br)c3c(c2)OCO3)cn1 +Cc1nc(-c2cc(C(=O)NCc3ncn(C)n3)n(C)c2)cs1 +CNc1ncc(Br)c2cccc(C)c12 +CC(=O)Nc1cccc(NCCC(=O)c2ccc(C)cc2)c1 +C=CCN(CC=C)C(=O)CNc1cccc(Br)c1 +O=C(c1cccs1)N1CCN(c2cnccn2)CC1 +CCCCN1C(=O)CCC2CN(C(=O)c3ccc(COC)o3)CCC21 +COc1ccc(S(=O)(=O)c2coc3ccc(C)cc3c2=O)cc1 +COC(=O)Cn1cccc(S(=O)(=O)N2CCC(C)CC2)c1=O +CC(C)NC(=O)CNc1ccc(C(=O)N(C)c2ccccc2)cc1 +Cc1c(C(=O)Nc2cccc3ncccc23)cnn1-c1ccncc1 +O=C(NC1CC1)c1cc(C(F)(F)F)cc(C(F)(F)F)n1 +CCN1CCc2nc(NC(=O)C3(c4ccccc4)CCC3)sc2C1 +COc1ccc(-c2nc(Cn3cc(Cl)c(=O)[nH]c3=O)co2)cc1 +CCC(C)NC(=O)C1CC(=O)N(c2ccccc2F)C1 +COc1ccccc1CNC(=O)CSc1nncn1C(C)C +CN1CCN(S(=O)(=O)c2cccc(C(=O)N(C)C)c2)CC1 +CCc1ncc(C(=O)N2CCN(c3nccs3)CC2)s1 +CC(C)c1cc(C(=O)N2CCOCC2CC(=O)c2ccccc2)on1 +Cc1cccc(C(=O)NC(C)C(=O)NCC(=O)Nc2ccccc2)c1 +O=S(=O)(NC1CCC(C(F)(F)F)CC1)c1cccc(F)c1 +Cc1ccc(C)c(NCC(=O)Nc2cc(C)on2)c1 +O=C(Nc1ccc(Br)cn1)N1CCOCC1 +Cc1ccc(C(=O)Nc2c(C)nc3cc(C)ccn3c2=O)cc1 +Oc1ccc(-c2nc(CCc3ccccc3)n[nH]2)cc1 +COc1ccccc1OCCNC(=O)c1cccc2ccnn12 +O=S(=O)(c1ccccc1)N1CCC(OCc2ccccc2F)CC1 +CCCN(Cc1ccc(C#N)cc1)C(=O)c1ccc(-n2cncn2)nc1 +CCOc1cc2c(c(Br)c1O)C(C)NCC2 +O=C(C1CC1)N1CCN(c2ccc(-c3ccc(Cl)cc3)nn2)CC1 +Cc1ccnc2nc(C(=O)NC(C)c3cc4ccccc4o3)nn12 +N#Cc1cccc(C(=O)N(Cc2ccoc2)Cc2cccs2)c1 +CC(NC(=O)C(C)c1ccsc1)c1ccc2c(c1)CCC(=O)N2 +C=CCOC(C)C(=O)Nc1cccc2c1OCCO2 +COc1ccc2nc(C(=O)NCc3ccc(Cl)cc3)cn2n1 +COc1ccc(-c2nc(-c3ccccn3)no2)cc1 +CNC(=O)c1ccc(NCC(=O)Nc2ccc(NC(C)=O)cc2)cc1 +CC1CN(C(=O)c2sccc2-n2cccc2)CCO1 +Cc1nnc(SCc2c(Cl)ccc3cccnc23)n(N)c1=O +Cn1ccc(NC(=O)COc2ccccc2Cc2ccccc2)n1 +CCOC(=O)C1CCCc2cnn(CC3CCCCC3)c21 +Cc1c(C(=O)NCCCCC(C)C)cnn1-c1ccncc1 +CCOCC1CCN(C(=O)Cc2ccc(F)cc2F)C1 +CCOc1ccc(NC(=O)CCOC)cc1CO +Oc1ccc2cc3c(cc2c1)C(c1ccncc1F)NCC3 +COC(=O)CCNC(=O)c1ccc2nccnc2c1 +c1cncc(-c2n[nH]c(SCc3nnc(C4CCC4)o3)n2)c1 +Cc1ncsc1C(=O)Nc1ccc(Cl)c(N)c1 +CC(=O)c1ccc2c(c1)N(CC(=O)NCCc1ccccc1)CCO2 +Cc1cnn(-c2ccccc2)c1NC(=O)c1ccoc1 +Cc1nc2ccc(NC(C)C(=O)Nc3ccccc3C#N)cc2s1 +COC(=O)C(Cc1ccccc1)NCc1ccco1 +Cc1csc(N2CCN(C(C(N)=O)c3ccccc3)CC2C)n1 +CC(Oc1ccc(-c2ccccc2)cc1)C(=O)NCC(N)=O +CCN(CC)S(=O)(=O)N(C)Cc1ccc(Cl)cc1 +O=S(=O)(N1CCOCC1)N1CCN(CCc2ccccc2)CC1 +Nc1ncnc2c1ncn2CCCSc1ncnc2ccsc12 +O=C(NCCOc1ccc(Br)cc1)NCC1CCC1 +O=C(Cc1cccnc1)NC1CCCC1Oc1ccccc1 +CC(=O)Nc1cccc(C(=O)OC(C)C(=O)NC2CC2)c1 +COc1ncnc2c1ncn2C1OC(CO)C(O)C1O +CC(C)NC(=O)NC(c1ccc(F)cc1)c1nccn1C +Cc1nnc2ccc(-c3noc(-c4ccc(F)c(F)c4)n3)cn12 +CCCS(=O)(=O)c1ccccc1C(=O)N1CCCC(O)C1 +COc1ccc(NC(=O)N2CCC(c3ccc(O)cc3)CC2)cn1 +O=C(Cc1ccccc1)Nc1ccc(C(=O)N2CCOCC2)cc1 +COc1cc(CCc2ccc3c(c2)OCO3)oc(=O)c1 +CCCNC(=O)NC(C)c1ccc(OC(F)F)cc1 +CCN(CC)S(=O)(=O)c1cc(C(=O)NC(C)C)ccc1C +CCc1nc(COc2ccccc2F)sc1C#N +Cc1nc(SCC(=O)C2=NC=CC2)n(C2CCCC2)c1C +CC(NC(=O)c1cc(Br)cn1C(C)C)C(=O)N(C)C +Cc1nc2ccccn2c1C(=O)NCCc1cccs1 +CN(CC1CC1)C(=O)COc1ccc(C#N)c(F)c1 +CN(C(=O)C1CCCN1C(=O)OC(C)(C)C)C1CCCCC1 +O=C(c1cc(Br)ccc1Cl)N1CCC(CO)CC1 +O=C(NCCN1CCc2ccccc21)c1onc2ccccc12 +Nc1c(-c2ccccc2F)noc1C(=O)N1CCCCC1 +CC(C)Oc1cccc(NCCN2CCOCC2)c1 +O=C1CC(CNC(=O)N(Cc2ccccc2)C2CC2)c2ccccc2N1 +COC(=O)CCC(=O)N(C)Cc1cccc(C(N)=O)c1 +O=C(NCC1CC=CCC1)c1scnc1C1CC1 +O=C(Nc1ccccc1N1CCOCC1)c1ccccc1F +CC1CN(CC(=O)N2CCCC2c2cccs2)CC(C)O1 +O=c1c2sccc2ncn1Cc1nc2ccccc2s1 +O=C(CC1CCc2ccccc21)NCCc1c[nH]c2ccccc12 +COC(=O)c1ccccc1NC(=O)Nc1cc(C)cc(C)n1 +COCc1noc(CCNC(=O)c2oc3cc(C)ccc3c2C)n1 +N#Cc1cccc(C(N)c2nc3c(s2)CCCC3)c1 +Fc1ccc(NCCN2CCOCC2)cc1Cl +C=CCn1c(SCc2cn3ccccc3n2)nnc1-c1ccncc1 +CCS(=O)(=O)N1CCN(C(=O)Cc2ccc(F)cc2)CC1 +Cc1cccc(=O)n1CCCCNC(=O)C1C(C)(C)C1(C)C +COc1cccc(CC(=O)N2CCC3(CC2)OCCCO3)c1 +COCc1ccc(C(=O)Nc2ccc(OCC(F)(F)F)nc2)o1 +OC(c1ccccn1)C1(c2ccccc2)CCOCC1 +Cc1ccc(NC(=O)CC2CC3CCC2C3)cc1S(C)(=O)=O +CN(C)C(=O)c1cccc(CCNc2ccc(C#N)cc2F)c1 +Nc1cnc(CCOc2cccc3c2CCCC3)nc1 +CC(C)(C)c1noc(CCCC(=O)N2CCCS2(=O)=O)n1 +Cc1cc(C(=O)NC(C)CC(=O)c2ccco2)nn1-c1ccccc1 +COCCCC(=O)NCc1ccc2ccccc2c1 +C=CCOc1cccc(NC(=O)N(C)Cc2ccccn2)c1 +O=C(NCCOc1cccc2ccccc12)c1cc[nH]n1 +Cc1ccc(-c2noc(-c3ccc4c(C)cc(C)nc4c3)n2)nn1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)OCc1ccc(F)cc1 +CC1CCC(NS(=O)(=O)c2c[nH]c(C(=O)N3CCCC3)c2)CC1 +NC(=O)COc1ccc(NC(=O)c2ccc(Cl)cc2F)cc1 +CCc1[nH]nc(C(=O)N(CC)CC(F)(F)F)c1N +O=C(c1cc(N2CCOCC2)ccn1)N1CCOCC1 +COc1cc[nH]c(=NS(=O)(=O)c2cc(Cl)cc(Cl)c2)c1 +CCCNC(=O)CNC(=O)c1cc(OC)ccc1O +COC(=O)c1csc(NC(=O)C2CCCN(C(=O)C3CC3)C2)c1 +Cc1cc(F)ccc1S(=O)(=O)N(Cc1ccsc1)C1CC1 +COC(=O)c1ccc(CS(=O)(=O)c2ccc(C(F)(F)F)cn2)o1 +COc1cc(C#N)ccc1OCC(=O)N(Cc1ccccc1)C(C)C +CC(=O)Nc1cccc(C(=O)N2CCOC(C)C2)c1 +CCOC(=O)c1cnn(-c2cnc3ccccc3n2)c1N +CCc1c(C)sc(NC(=O)Cc2cccc(OCC#N)c2)c1C#N +CCCCS(=O)(=O)NCC(=O)N1CCOC(c2ccsc2)C1 +CCn1c(SCc2ccccn2)nnc1-c1ccc(OC)cc1 +COCc1ccccc1NC(=O)c1cccc(OCC(N)=O)c1 +CCC(=O)Nc1cccc(C(=O)N(CC(F)(F)F)C(C)C(C)C)c1 +COc1cc(Cl)cc(C(=O)N2CCOCC(CO)C2)c1 +CN(CC(=O)N1CCC1c1ccccc1)c1ncnc2[nH]cnc12 +O=C(CCc1ccsc1)Nc1ccc(-n2ccnc2)nc1 +Cc1cc(N)nc(SCC(=O)Nc2ccccc2SCC#N)n1 +CC(=O)Nc1ccc(F)c(NC(=O)Cc2ccccc2)c1 +Cc1cccc(CN2CCN(C(=O)CCn3cncn3)CC2=O)c1 +Cc1cc(CN(C)C(=O)c2ccc(N(C)C)cc2)no1 +CC(=O)N1CCC(NC(=O)N(C)CCc2ccc(F)cc2)CC1 +CC1(C(=O)NCc2ccncc2)Cc2ccccc2C(=O)O1 +CCc1onc(C)c1NC(=O)NCC(C)CC1(C)OCCO1 +CN(C(=O)c1cnn2c1OCCC2)C1CCCCC1 +CC(=O)NC1CCN(c2cccc(OC(F)(F)F)c2)C1=O +CCC1C=CCN1C(=O)Nc1cc(C(C)(C)C)nn1C +CCCn1nnnc1NC(=O)c1ccc(-c2ccc(Cl)cc2)o1 +Cc1ccc(CNC(=O)N2CCN(CC(=O)NC(C)C)CC2)cc1 +NC(=O)C1CCN(C(=O)CCc2nc(-c3ccncc3)no2)CC1 +CN(C)C(=O)C1CCN(c2ccccc2F)CC1 +Cc1cc(NC(=O)CCc2cccc(Cl)c2)[nH]n1 +COc1ccsc1C(=O)NCC(C)(C)N1CC(C)OC(C)C1 +O=C(Nc1ccc(NC(=O)C2CC2)cc1)c1cccnc1 +CC(=O)Nc1ccc(-c2nc3ccc(C)cn3c2N)cc1 +CC(C)NC(=O)CC1(C(=O)Nc2ccc(C(N)=O)cc2)CCCC1 +CCCN(C)C(=O)NCc1cn(-c2ccccc2)nc1-c1ccncc1 +COc1ccc(C(=O)C(C)OC(=O)c2ccc(C)o2)cc1 +CCc1noc(C)c1C(=O)Nc1nc(-c2ccccc2)c(C)s1 +CC1CCCC(C)N1CC1=NS(=O)(=O)c2ccccc2N1 +O=C(COC1CCCC1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)c1ccc(C#N)cc1 +COc1ccc(F)cc1Cc1nc(-c2cccc(N)c2)cs1 +COCc1nc2c(NC(=O)C3CCCCC3)cccn2n1 +COc1ccc2c(c1)c(=O)ncn2-c1cccc(Cl)c1 +Cc1ccc(C)c(CN(C)Cc2nnc(C)n2C)c1 +CC(=O)Nc1cccc(C(C)OC(=O)c2cc(C(N)=O)cn2C)c1 +Nc1cc(Cl)cnc1N1CCN(c2ccccc2)CC1 +CCC(C)(CO)NC(=O)NCc1ccccc1Cl +CCn1ncc(NC(=O)Cn2ccc(-c3cccn3C)n2)n1 +COCc1noc(CN2CCN(CC(C)C)C(=O)C2C)n1 +COc1cc(C(C)NC(=O)Cn2ccccc2=O)ccc1OC(C)C +Cc1ccc(C(=O)N(Cc2ccco2)CC2CCCO2)s1 +CCC(C)NC(=O)CN1CCNc2cc(C)c(C)cc21 +CCC(C)NC(=O)NCCc1c(C)nn(C)c1C +OCC#Cc1cc(F)ccc1CSc1ncn[nH]1 +Cc1cccc(C)c1NC(=O)c1cccc2c1OCO2 +COc1ccc(Cl)cc1NC(=O)Nc1cc[nH]n1 +CCNc1ccc(C(=O)N(CCO)C(C)C)cn1 +O=C(NCCc1cccnc1)C1CCCc2ccccc21 +CCOC(=O)CSc1nncn1-c1ccccc1 +C=CCNc1cnn(-c2ccc(OC)cc2)c(=O)c1Cl +Nc1c(NCCN2CCOCC2)ncnc1NCC1CCCO1 +Cc1ccccc1C(C)NC(=O)c1nn(C)c(=O)c2ccccc12 +C#CCNC(C(=O)OCC)c1ccc(OC)c(O)c1 +CCNC(=O)N1CCN(Cc2cc(F)cc3cccnc23)CC1 +Cc1ccc(C(C)C)cc1CC(=O)N1CCC(=O)CC1 +CC(=O)N1CCCC(S(=O)(=O)NC(c2ccccc2)C2CC2)C1 +CC(C)c1ccccc1OCCc1nc(C#N)cs1 +COCCn1cc(NC(=O)C2CC(=O)N(Cc3ccccn3)C2)cn1 +CCC(C)C(=O)C(C#N)c1nnc2n1CCCCC2 +Cn1ccnc1C(NC(=O)c1ccccc1Cl)c1ccccc1F +CC(Sc1nnc(NCc2ccc(F)cc2)s1)C(N)=O +O=C(NCCc1csc(-c2ccccc2)n1)NCc1cc[nH]n1 +Cc1nn(C)c2sc(C(=O)NC(C)c3ccccc3)cc12 +COc1cccc(C(=O)NCCC(=O)Nc2ccc(Cl)cc2)c1 +O=C(C1CCC1)N1CCCN(c2ccncn2)CC1 +Cn1ncc2c(N3CCCC3c3nnc4n3CCCCC4)ncnc21 +CC(=O)NC(C)C(=O)Nc1ccc2c3c(cccc13)CC2 +CCn1nc(C(=O)N2CCOCC2)c2ccccc2c1=O +COc1cc(CNc2cccc(SC)c2)cc2c1OCO2 +CCn1cc(NC(=O)c2ccc(Br)cc2O)ccc1=O +CCC1CN(C)c2ccccc2CN1C(=O)NCc1cnc(C)s1 +COCCN(Cc1ccncc1)C(=O)C1COc2ccccc2C1 +NC(=O)CN1C(=O)N2CCN=C2c2cnn(-c3ccccc3)c21 +Nc1ccc(-c2nnc(Cc3c(F)cccc3F)o2)cc1 +O=C(NCCCN1CCOCC1)NC1COc2ccccc2C1 +COCCNC(=O)c1nccc2c(N)c(OC)c(OC)cc12 +CC(C(=O)NC1CCCCC1)N(C)Cc1nc2ccccc2c(=O)[nH]1 +NS(=O)(=O)c1ccc(CNC(=O)Nc2ccncc2)s1 +Cc1cc(C)c(C(=O)Nc2ccc(OC(C)C)c(Cl)c2)c(=O)[nH]1 +OCc1cc2cc(-c3ccc4c(c3)OCCO4)ccc2[nH]1 +O=C(NCC1CCCO1)c1n[nH]c2ccc(Br)cc12 +O=C(Nc1nc(-c2c[nH]c3ccccc23)cs1)c1ccoc1 +COC(=O)c1cc(N)cc2c1Oc1ccccc1O2 +CC(=O)c1c(SCC(=O)NC2CCCCC2)nc(=O)[nH]c1C +CC1CCCC(NC(=O)CCCC(=O)NC2CCCC(C)C2)C1 +CCC1CN(C(=O)c2cn(-c3ccc4c(c3)OCCO4)nn2)CCO1 +CCOc1ccc(NS(=O)(=O)c2cc(F)ccc2F)cc1 +CCCC(=O)N1CCc2cc(-c3csc(C)n3)ccc21 +CC(=O)c1cccc(OCc2nc(N)nc(N(C)C)n2)c1 +Cc1cc(C(=O)Nc2nc(CC(C)C)n[nH]2)c2c(C)noc2n1 +COc1ccc2nc(SCC(=O)Nc3ccccc3C#N)[nH]c2c1 +CCCNC(=O)C1CCCN(C(=O)NC2CCc3ccccc32)C1 +CCCNC(=O)c1nc(Cn2cnc3ccccc3c2=O)no1 +CCS(=O)(=O)N1CCCC1c1ccc(Cl)cc1 +COc1ccc(SCC(=O)NCc2cccc(C(N)=O)c2)cc1 +Cc1nc(-c2ccc(S(=O)(=O)N3CCOCC3)cc2)cs1 +CS(=O)(=O)N1CCN(c2c(Cl)cncc2Cl)CC1 +COc1ccc2c(CC(=O)N3CCNC(=O)C3)coc2c1 +CCS(=O)(=O)N(C)C(C)c1ccc(Cl)cc1 +OCCn1nncc1-c1ccc(Cl)c(Cl)c1 +CC(C)(C)C(CCO)NC(=O)NCc1ccc(F)cc1 +CCOc1ccccc1Nc1ncnc(-n2ccnc2)c1N +Cc1ccc(S(=O)(=O)N2CC3CCC2C3OCC(C)C)cc1 +Cc1cccc(NC(=O)Cn2nc(-n3nc(C)cc3C)ccc2=O)n1 +COc1cc(C)c(NC(=O)c2cn(C)nc2C(C)(C)C)cc1OC 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+COc1ccc(CN(C(=O)c2ccc(=O)n(C)c2)C2CC2)cc1 +CC(C)(C)OC(=O)N1CCN2C(CO)CCC2C1 +Cn1nnnc1SCC(=O)C12CC3CC(CC(C3)C1)C2 +CC(=O)N1CCCN(CCCNC(=O)C2CCCC2)c2ccccc21 +Cc1cc(N(Cc2cccnc2)Cc2ccco2)ncn1 +CC(C)CC(=O)N1CCC(NC(=O)c2ccc3c(c2)OCCO3)CC1 +CCC(=O)Nc1cc(S(N)(=O)=O)ccc1OC +N#Cc1cccc(C2NCCc3cc(F)c(O)cc32)c1 +O=C(C1CCCN1c1nnc(N2CCCC2=O)s1)N1CCCC1 +O=C(NCCOc1cccc(Cl)c1)Nc1cn[nH]c1 +Cc1cc(C(=O)OCC(=O)Nc2oc(C)c(C)c2C#N)on1 +CC1CN(C(=O)Nc2cccc(C#N)c2)CC(c2ccccc2)O1 +COc1ncccc1CNC(=O)NC(C)CCc1cccn1C +COc1ccccc1-c1ncc(-c2cn(CC(O)CO)nn2)s1 +O=C(c1ccco1)N1CCOCC1c1nccc(N2CCOCC2)n1 +CCc1ccccc1N1Cc2ccccc2OCC1=O +CC(C)C(=O)N1CCCc2cc(NC(=O)C3CC3)ccc21 +CCc1cc(=O)[nH]c(Cc2c(F)cccc2Cl)n1 +C=CCn1c(C)nnc1SC(C(N)=O)c1ccccc1 +CCCCN(CC(F)(F)F)C(=O)c1cc(C)sc1C +CCOC(=O)NCCC(=O)Nc1cccnc1N1CCCC1 +CCCCCNC(=O)Cn1c(=O)oc2cc(Cl)ccc21 +Cc1cccc(OCC(=O)N(CC2CCCO2)c2ccncc2)c1 +CCOC(=O)CN(C)C(=O)c1ccc(Cl)cc1N +CCc1nc2n(n1)CCCC2NC(=O)CC(C)c1ccccc1OC +CCCn1c(N)c(C(=O)CN2CCC(OC)CC2)c(=O)[nH]c1=O +CC(Cc1cnccn1)NC(=O)c1cnc(Nc2ccccc2)nc1 +Cc1cccc(NC(=O)Cn2c(=O)n(C)c(=O)c3sccc32)c1 +c1cc(-c2noc(CSc3nnnn3C3CCCCC3)n2)cs1 +CC(=O)Nc1ccc(Br)cc1NC(=O)c1ccc(C)cn1 +CC1(C)Cc2cccc(OCC#CCNC(=O)c3ccno3)c2O1 +C#CCNC(=O)C1CC(=O)N(c2ccc(CC)cc2)C1 +CS(=O)c1ccc(NCc2ccccc2-n2cccn2)cc1F +O=C(NCC1COCCO1)c1cc(Cl)ccc1O +COc1ccccc1-c1nnn(-c2ccccc2F)c1N +CSc1nc(C(=O)N2CCN(c3ccc(C)cc3)C(=O)C2)cs1 +N#Cc1nccnc1N1CCOC(CCc2ccccc2)C1 +O=C(Cc1ccc[nH]1)N(Cc1ccccc1)Cc1ccco1 +FC(F)(F)Oc1cccc2c1C(C1CCCO1)NCC2 +CCc1ccccc1Nc1ncnc(N2CCCC2)c1N +Cc1c(C(=O)N2CCCCC2)nnn1Cc1ccccc1 +Cc1cc(-n2ccnc2)n2ncc(-c3ccccc3)c2n1 +COc1ccc(C(C)C)cc1S(=O)(=O)Nn1cnnc1 +CC(C)(C)CCNC(=O)CNC(=O)c1ccccc1Br +CS(=O)(=O)c1cccc(OCC(=O)c2ccc(F)c(F)c2)c1 +COc1ccc(CN(C)S(=O)(=O)c2c(C)noc2C)cc1F +O=C(NC1CC1)C1CNCCN1C(=O)c1c[nH]c(=O)cn1 +O=C(NCC1CCCCC1)c1ccc2ncccc2n1 +CC(C)CCNC(=O)NC(CN1CCOCC1)c1ccccc1 +O=C(CSc1ncn[nH]1)Nc1nonc1-n1cccc1 +Nc1cc[nH]c1Cc1ccc(Br)cc1 +CCCc1ccc(S(=O)(=O)NCc2cnc(C)s2)cc1 +CC(CNC(=O)N(C)CC1CCCCO1)Cn1cccn1 +Cn1ncc2c1C(COCC1CC1)N(C(=O)Cc1ccsc1)CC2 +C=CCSc1nc2c(c(=O)n(C)c(=O)n2C)n1CC=C +CN1C(=O)CCc2cc(NC(=O)NCCc3ccccc3)ccc21 +Cc1ccc(Cn2cnc3c2c(=O)n(C)c(=O)n3C)cc1 +C=C(C)COc1cccc(NC(=O)NCc2nncn2C2CC2)c1 +COCCn1ccc2c(nnc3c(-c4ccc(F)cc4)cnn32)c1=O +CCC1CCC(N(C)C(=O)c2ccc(N)cc2)CC1 +COC(=O)c1ccc(-c2noc(-c3ccnnc3)n2)cc1 +O=C(CC1NC(=O)c2ccccc21)Nc1cccc(Cl)c1 +Brc1ccccc1OCc1nc2c(s1)CCN2 +CCOC(CC)C(=O)Oc1ccc2c(C)cc(=O)oc2c1 +COc1cccc(C(=O)Nc2cccc(C(C)=O)c2)c1O +Cc1nccn1-c1ncc(NC(=O)COc2ccc(Cl)cc2)cn1 +Cc1ccsc1CNC(C)c1cnc(-c2ccncc2)nc1C +CC(=O)c1ccccc1NC(=O)C(C)OC(=O)c1ccccc1O +Cc1nc(NCCNC(=O)c2ccccc2)cc(-n2cccn2)n1 +CS(=O)(=O)NCCCNC(=O)c1ccc(Cl)cc1Cl +CC(=O)c1ccc(C(=O)N2CCC(OCc3ccccc3)CC2)s1 +FC(F)(F)c1ccc2c(c1)nc(C1CC1)n2C1CC1 +COCCC(=O)N1CCN(c2ccc(C#N)cn2)CC(O)C1 +COc1ccc(-c2cc(COC(=O)c3snnc3C)no2)cc1 +COC(=O)N1CCC2Nc3ccc(Cl)cc3C2C1 +CCC1CN(C(=O)c2sccc2C2CC2)CC1N1CCOCC1 +CCC(CO)NC(=O)Cc1ccc(NC(=O)c2cccn2C)cc1 +Cc1ccccc1CNC(=O)COC(=O)c1sccc1C +CCNS(=O)(=O)c1ccc(C)c(C(=O)NCCC(C)C)c1 +CCc1onc(C)c1NC(=O)NCCC(=O)Nc1cccc(C)n1 +Cc1cc(F)ccc1NC(=O)c1cc(C(C)C)on1 +CC1Oc2ccc(C=CCCC(C)(C)O)cc2N(C)C1=O +CCC(=O)Nc1ccccc1Cc1nc(-c2cccnc2)no1 +CCCCN(C(=O)C1CC(=O)N(CC)C1)c1ccccc1 +N#Cc1c(CN2CCSc3ccccc32)cn2ccccc12 +O=C(NCCC(O)C1CC1)c1ccc(Cl)cc1Cl +CCN(CC)c1cccc(OC(C)C(=O)OC)c1 +CC(=O)Nc1cccc(NC(=O)Nc2cccc(C(N)=O)c2)c1 +CC(=O)c1cccc(NCCC(O)c2ccc(Cl)cc2)c1 +COCCc1ncc(C(=O)NCc2ccco2)c(N)n1 +Cc1ccc(OCc2cc(C(=O)N(C)Cc3nnc(C)o3)no2)cn1 +COC(=O)c1cccnc1NC(=O)Cc1c(C)nc2ccccc2c1C +O=C(CSc1nc(=O)[nH]c2c1CCC2)Nc1ccc(Cl)cc1 +O=C(CNC(=O)c1cnc2cccnn2c1=O)Nc1cccnc1 +CCN(CC)S(=O)(=O)c1ccc(CNC(=O)C(C)(C)C)cc1 +CC(Sc1ccc(F)c(F)c1)C(=O)N(C)CCC#N +CC(NC(=O)c1ccc(N2CCOC2=O)cc1)c1ccccc1 +COC(=O)CNc1ccc(Br)c(C)c1 +CC(=O)c1ccc(NS(=O)(=O)N2CCC(C)CC2)cc1 +CCc1nnsc1C(=O)N1CCN(C(C)c2ccccc2F)CC1 +O=C(Nc1ccc2c(c1)OCO2)c1cc(-c2cccc(O)c2)on1 +CCCC1CN(C(=O)c2cccc(-n3ccnc3SC)c2)CCO1 +CC(=O)Nc1ccc(-c2nc3ccccc3o2)c(O)c1 +CC(C)(C)C(=O)Nc1nc(-c2ccc3c(c2)OCCO3)cs1 +O=C(CC1CCCCC1)NCC(=O)Nc1c[nH]ccc1=O +Cc1ccc(S(=O)(=O)NCCc2cn3c(C)csc3n2)cc1 +Cc1ccc(C)c(N2CCN(C(=O)c3cccs3)C(C)C2=O)c1 +O=C(NCc1ccccc1F)c1c(-n2cnnn2)sc2c1CCC2 +COc1cc2nc(-c3cccc(C)c3)n(CCCO)c2cc1OC +CCCNC(=O)NCC1(O)CCc2ccccc2C1 +CC(C)(C#N)C(=O)N1CC=C(c2ccc(F)cc2)CC1 +CC(C)Oc1ccc(F)cc1NC(=O)C1CC(=O)N(C2CC2)C1 +COc1ccccc1NC(=O)N1CCC2(CC1)OCCO2 +C=CCOC(C)C(=O)Nc1cc(Cl)ccc1C(=O)NC +CCC(NCc1ccco1)C(O)c1ccc(F)cc1 +CNc1ncccc1S(=O)(=O)NCC1CCCCO1 +NC(=O)C(NC(=O)c1csc(-c2ccco2)n1)c1ccccc1 +CCn1nc(C)cc1C(=O)Nc1cccc(CN2CCOCC2)c1 +Cc1ccn2cc(C(=O)Nc3cccc(-c4ccnc(C)n4)c3)nc2c1 +CC(C)Oc1ccc(NC(=O)NCC2CCOC2)cc1 +CC(N)C(=O)c1noc2ccc(Br)cc12 +CC(C)N(C(=O)c1cc(-c2ccccc2)[nH]n1)C1CCC1 +CCc1ccc(CCC(=O)NCC(O)c2ccco2)cc1 +CC(=O)Nc1ccc(F)c(C(=O)NCc2cccc3ccccc23)c1 +COc1ccc(NC(=O)COc2cccc3c2CCN(C)C3=O)cc1 +O=C(Oc1ccccc1F)c1cnc2ccccn2c1=O +O=C(Cc1noc2ccccc12)N1CCCCC1c1nc[nH]n1 +CCCc1nnc(NC2CCN(C(=O)c3ccccc3)CC2)o1 +CSc1nccc(N2CC(NC(C)=O)C(C(C)C)C2)n1 +COc1ccccc1C(C)(C)CNS(=O)(=O)N(C)C +CNC(=O)c1oc(-c2ccc(Cl)cc2)nc1C +COc1ccc(CN(C)C(=O)Nc2cc(F)c(OC)cc2OC)cc1 +CCOC(=O)Nc1cccc(C(=O)OCc2cc(C)no2)c1 +Cc1ccc2nnc(C(=O)Nc3cccc(C#N)c3)n2n1 +CC(=O)NCC(=O)NC1CCN(c2cc(C)ccc2F)CC1 +COc1ccc(S(=O)(=O)N(C)Cc2ccc(C)o2)cc1OC +CC(NC(=O)NCc1ncn(C)n1)c1ccc(C(F)(F)F)cc1 +O=C(NCc1ccc(-c2ccn[nH]2)cc1)c1cccc(-c2ncon2)c1 +O=C(NCc1nnc2n1CCCCC2)NC1c2ccccc2CC1O +CCN(CC)C(=O)CN(C)C(=O)c1cn(C)nc1C(C)(C)C +CCn1c(=O)n(CC(O)CN2CCOCC2)c2ccccc21 +Cc1sc(=O)n(CC(=O)OCc2ccc(F)cc2)c1C +Cc1ccc(NC(=O)CNC(=O)c2ccc3ccccc3c2)nc1 +Cc1c(C(C)NC(=O)c2ccn(C)c(=O)c2)oc2ccc(F)cc12 +COC(=O)C1CN(Cc2cnn(Cc3ccccc3)c2)CC(C)O1 +O=S(=O)(CCSc1nnc(C2CC2)n1C1CC1)c1ccccc1 +CS(=O)(=O)N1CCCN(C(=O)c2cccc(Cl)c2)CC1 +Cc1cccc(NCC(=O)NC2(C#N)CCCC2)c1C +CCOCC(=O)Nc1ccc(OC)c(OCC)c1 +CN(C)c1cccc(N(C)C)c1CNC(=O)C(C)(C)C +CC1CN(C)CC(C)N1C(=O)c1cnc(C2CCCO2)s1 +CCN(C)C(=O)c1ccc(N2CC3C4CCC(CC4)C3C2)nc1 +CCNC(=O)C1(NC(=O)c2cn3ccccc3n2)CCCCC1 +C=CCN1COc2c(cc3c4c(c(=O)oc3c2C)CCC4)C1 +CCCOc1cccc(NC(=O)N2CCCN(C(=O)OC)CC2)c1 +CC(C)(C)OC(=O)n1ccc2c(F)c(F)ccc21 +Cc1cc2ccccc2n1CCNC(=O)c1cc2ccccc2oc1=O +COc1ccc(CNc2cc(OC)c(Cl)cc2OC)cc1O +COCCn1nc(C(=O)Nc2cc(C)on2)ccc1=O +CCCCN(C)C(=O)C1CCN(C2CC(C)OC2=O)CC1 +COC(=O)c1sc(NC(=O)Cc2c(F)cccc2Cl)nc1C +CCOc1cccc2sc(NC(=O)c3cc(C)on3)nc12 +COCCn1c(C(=O)NCc2cccnc2)cc2ccccc21 +COCC(C)NC(=O)Cn1nc(C(F)(F)F)cc1C +CC(NC(=O)c1ccccc1Br)C1CCCO1 +CN(Cc1ccc(OC(F)F)cc1)C(=O)NCc1cscn1 +CC(=O)Oc1ccccc1C(=O)c1ccc(C)cc1 +Cc1ncc(CN(C)Cc2ccc(-n3ccnc3)cc2)s1 +COc1ccc(-n2nnnc2SCC(=O)NC(C)C(C)C)cc1 +COc1ccc(CNc2ccc3[nH]nc(C(N)=O)c3c2)c(OC)c1 +CC(C)(C)C(=O)Nc1ccc(C(=O)Nc2ccc(O)cc2)cc1 +O=C(NCCO)NCc1cccc(NC(=O)c2ccc(F)cc2)c1 +CCCCN1CC(c2nc3ccccc3[nH]2)CC1=O +CC(=O)Nc1ccc(CCNC(=O)NCc2ccsc2)cc1 +Clc1cccc(CN2CCN(c3cnn4cnnc4c3)CC2)c1 +COCCOc1ccccc1NC(=O)N(C)CC1CC1 +O=C(NCCc1cccnc1)N1CCc2cc(F)ccc2C1 +CCN1CCN(C(=O)CCCC(=O)N2CCN(CC)CC2)CC1 +O=c1[nH]c(CO)nc2sc(-c3ccccc3)cc12 +CCCC1CN(C(=O)CCc2c(C)nc(SC)[nH]c2=O)CCO1 +CNC(=O)NCC(=O)NCC(C)N(C)c1ccccc1 +Cc1nc(-n2cccc2)sc1C(=O)Nc1ccc2c(c1)OCCO2 +CSc1ccc(S(=O)(=O)Nc2cccc(C(N)=O)c2)cc1 +COc1c(F)c(F)cc(C(=O)NC(C)(C)CO)c1F +CC(C)CCc1noc(CNc2cc(C#N)ccc2Cl)n1 +Cn1cnc(CNS(=O)(=O)c2ccccc2Cl)n1 +Cc1cc(C)n(C2CCN(C(=O)c3cc(-c4ccc(C)o4)n[nH]3)C2)n1 +COc1ccc(C(=O)NC2CCSc3ccc(F)cc32)nn1 +NS(=O)(=O)c1ccc(C(=O)NC2CCCCCC2)o1 +CS(=O)(=O)N1CCCC(C(=O)NC2CCCCC2O)C1 +O=C1CN(C(=O)COc2ccc(-c3nnco3)cc2)CCN1 +CCc1noc(CNc2ccc(Cl)c(F)c2)n1 +Cc1nnc(SC(C)C(=O)c2cccc(Cl)c2)n1C +Cc1cc(C(=O)NCC(C(C)C)N2CCOCC2)c(C)o1 +CN(C)c1c(Cl)cccc1NC(=O)NCC(=O)N1CCCCC1 +CCCC1CCN(C(=O)c2ccc(NC)cc2)CC1 +O=C1OCCN1CCc1nc(-c2cc3cc(Cl)ccc3o2)cs1 +Cn1nnc2cc(C(=O)NCc3ccnc(OC(C)(C)C)c3)ccc21 +COc1ccc(C(N)C(F)(F)F)cc1C(C)(C)C +CCCC1CN(C(=O)C2(C)Cc3ccccc3C(=O)O2)CCO1 +O=C(NCc1ccccc1-c1ccccc1)c1cc2cc(=O)[nH]cc2[nH]1 +CC(=O)N(C)C1(c2ccccc2)CCN(C(=O)OC(C)(C)C)CC1 +Cc1ccc(CNC(=O)c2cccc(OCc3nnnn3C)c2)o1 +C#Cc1cccc(N(Cc2ccon2)Cc2cccs2)c1 +CC(=O)Nc1nc(COC(=O)c2ccc3nccnc3c2)cs1 +CCOC(=O)CCN1CCN(c2ncc(Cl)cc2Cl)CC1 +CNc1snc(C)c1C(=O)NC1COc2ccccc21 +NC(=O)c1ccc2c(c1)n(CC1CC1)c(=O)n2C1CCCCC1 +CN(C(=O)c1cc(C(N)=O)cn1C)c1ccc(F)c(F)c1 +COc1cc(-c2cnn3cccnc23)c(Cl)cn1 +COC(=O)CCNc1ccc2c(c1)CCN2C(C)=O +CC(NC(=O)CCc1ccco1)c1ccc(S(N)(=O)=O)cc1 +Cc1cc(-c2nnc(NC(=O)Nc3ccc4c(c3)OCO4)o2)nn1C +CC(NC(=O)CNC(=O)c1cccs1)c1nc2ccccc2o1 +COC(=O)c1nn(-c2cc(Cl)cc(Cl)c2)nc1C +CCOc1ccc(C(=O)N2CCN(c3ncccn3)CC2)cn1 +COCCNc1nc(C)nc2c1oc1ccccc12 +O=C(c1coc2ccccc12)N1CCCS1(=O)=O +CCCN(CC1CC1)C(=O)Nc1cnn(-c2ccccc2F)c1 +Cc1csc(=O)n1CC(=O)Nc1nnc(C2CC2)s1 +NC(=O)C1Cc2ccccc2CN1C(=O)CCc1c[nH]c2ccccc12 +Cc1nc(C)c(C2NCCc3c(C)cccc32)s1 +CCOC1CCCN(C(=O)c2cccc(-c3ccoc3)c2)C1 +NC(=O)NCCC(=O)Nc1cccc(NC(=O)C2CC2)c1 +O=C(C#Cc1ccccc1)NC1CCN(c2c(F)cccc2F)C1=O +Cn1c(C(=O)NCc2ccc(Cl)cc2)nc2ccccc2c1=O +CCc1ccc(CC(=O)Nc2nnc(-c3csc(C)n3)o2)cc1 +COc1ccc(-n2ccnc(NCc3ccc(F)cc3)c2=O)cc1 +COC(=O)C(C)NC(=O)C(C)NC(=O)OC(C)(C)C +COc1ccc(-n2nnc(C(N)=O)c2C)cc1OC +O=C(NC1CCOC(C2CC2)C1)NC1CCc2cc(Cl)ccc21 +Cc1ccccc1S(=O)(=O)CC(=O)N1CCCC1c1cccs1 +Cn1nccc1CNC(=O)Nc1ccc(F)c(F)c1 +Cn1cccc(NC(=O)Cc2ccc(Cl)c(Cl)c2)c1=O +COc1cc2c(cc1OC)CN(c1ncnc3oc(C)nc13)CC2 +Cc1nc(SCc2ccc(F)cc2F)[nH]c(=O)c1CCO +O=C1CCC(C(=O)N=c2[nH]c3ccccc3n2-c2ccccc2)N1 +CCN1CC(C(=O)N2CCCSc3ccccc32)CC1=O +C#CCn1c(=O)c(-c2ccccc2)nc2cc(F)ccc21 +Cc1cc(C)c2c(NC(=O)Cc3ccccc3)nn(C)c2n1 +Cc1nc(C(=O)NC2CCC(C(F)(F)F)CC2)cs1 +CCOC(=O)c1ccc(NC(=O)c2ccnn2CC)cc1 +COc1cccc(CNC(=O)CSc2nncn2C)c1 +CC(C)(C)C(C#N)NC(=O)CCc1cc(Cl)cs1 +Cc1csc(SCC(=O)NCc2cccs2)n1 +Cc1cc(NC(=O)C2CCN(c3ccc(Cl)cn3)CC2)n(C)n1 +NC(=O)COc1ccccc1C(=O)NC1CCSc2ccccc21 +CC1CCN(C(=O)CN2CCNc3ccccc32)CC1 +CC(Oc1ccc2c(c1)CCC2)C(=O)NCC(F)(F)F +CCN(Cc1cccs1)C(=O)CNC(=O)c1ccccc1Cl +Cc1nc(-c2c(C)c(C)nn(C)c2=O)sc1C(=O)NCC(C)C +COC(C)c1nc(C)c(C(=O)Nc2cc(C#N)ccc2Cl)s1 +COc1cc(CNc2ncccc2Cl)ccc1O +CC1CN(C(=O)c2ccccc2C#N)CCC1(O)C1CCOCC1 +CC(=O)NCC(=O)N(C)Cc1ccccc1Cl +O=C1CNc2cc(F)ccc2N1Cc1ccc(F)cc1 +O=C(NCCCOc1ccc2c(c1)OCO2)c1ccnc2[nH]ccc12 +COCCn1cnnc1SCc1ccc(C(=O)N2CCCC2)cc1 +C=CCNC(=O)COc1ccc(NC(=O)c2ccccc2Cl)cc1 +CCn1c(SCc2ccccc2C(=O)NC2CC2)nnc1C(C)C +CSc1nnc(CSc2ncccn2)n1C +CC(=O)NC(C(=O)NCCCC1CCCC1)C(C)C +O=C(NCCCc1ccc(Cl)cc1)NCCc1nnc2n1CCC2 +COc1cccc(OCC(=O)N(C)CCC(C)C)c1 +Cc1ccc(NC(=O)N(C)C(C)c2ccccn2)cc1S(C)(=O)=O +O=C(COc1cccc2ccc(=O)[nH]c12)Nc1cccc(Cl)c1 +C=CCN(CC=C)C(=O)c1ccc(F)cc1Br +Cc1n[nH]c(-c2ccc(NC(=O)c3ccc(-n4ccnn4)cc3)cc2)n1 +Cc1cccn2cc(CSc3nc4ccccc4n3CCC#N)nc12 +Cc1noc2nc3c(c(C(=O)Nc4nncs4)c12)CCC3 +N#Cc1ccc(CC(C#N)C(=O)N2CCCCCC2)cc1 +COc1ccc(Cl)cc1NC(=O)c1ccc(C)nc1 +COC(=O)N1CCC(NC(=O)Nc2ccccc2Cl)CC1 +CCC(C)C(O)CNS(=O)(=O)c1cc(C)c(C)s1 +COC1(CNC(=O)c2ccccc2C(C)=O)CCC1 +COC(=O)c1ccccc1NS(=O)(=O)c1ccccc1C +O=C(CN1CCOC(Cn2cncn2)C1)Nc1nccs1 +COc1cc(OC)cc(C(=O)N2CCN(C(=O)CC(C)C)CC2)c1 +CN(Cc1ccsc1)C(=O)c1cccc(-n2cccn2)c1 +COc1cccc(CN(C)C(=O)COc2ccc(F)c(F)c2)c1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ncccc2C)c1C +CC(C)NC(=O)CN1CCOCC1c1noc(-c2ccccc2)n1 +COc1ccc(CN(C)C(=O)C2CCC2)c(OC)c1 +N#CCc1cnn(-c2cccc(F)c2)c1C(F)(F)F +O=C(Cn1c(=O)sc2ccccc21)Nc1ccc(F)c(F)c1 +CC(C)CCNC(=O)CSc1nc2ccccc2c(=O)[nH]1 +Cc1cccc(-c2nc(C(C)C)no2)c1NC(=O)c1ccncc1F +CCOc1ccc(S(=O)(=O)n2ccc(C)n2)cc1CC +CC(=O)c1cccc(NS(=O)(=O)c2ccc(F)c(Cl)c2)c1 +Cc1nc(C)n(C2CCCN(C(=O)c3ncoc3C3CCCO3)C2)n1 +COCC(C)NC(=O)c1ccc(CN2CCCC2=O)cc1 +O=C(CCNC(=O)c1cccs1)NC12CC3CC(CC(C3)C1)C2 +OC(c1ccccc1)(c1ccc(Cl)cc1)c1ncc[nH]1 +Cc1noc(C)c1CC(=O)NCCC(=O)NC1CCCC1 +CCCC(=O)NCC(=O)N1CCCCCC1c1ccco1 +COC(=O)c1sccc1CN(C)c1c(C)noc1C +CC(C)Oc1ccc(C(=O)NCc2cccs2)cc1 +O=C(NCCC1CCCO1)C1CC(=O)N(c2cccc(Cl)c2)C1 +Cc1ccc(F)cc1S(=O)(=O)N(C)Cc1cccs1 +Cc1ccsc1CN(C(C)C)S(=O)(=O)c1cn[nH]c1 +CCn1nccc1CNC(=O)c1c(C)nn(C)c1C +Cc1ccc(S(=O)(=O)NCCn2c(C)nc3ccccc32)cc1C +CCS(=O)(=O)c1ccc2oc(Cn3nnnc3C(C)(C)C)nc2c1 +CCc1nnc(NC(=O)CSc2nc3cc(C)ccc3[nH]2)s1 +COCCCNC(=O)c1sc(NC2CCCCC2)nc1C +Cc1nc(-c2cccc(CNC(=O)C3CC34CCOCC4)c2)n[nH]1 +CCOC(=O)CC(C)(O)c1ccc(OC(F)F)cc1 +C=CCNC(=O)c1ccccc1S(=O)(=O)N1CCCCC1 +Cc1cc2cc(NC(=O)N3CCC(CC(=O)N(C)C)CC3)ccc2[nH]1 +CC#CC1NCCc2cc(OC)c(OC(C)C)cc21 +Cc1cccc(C(C#N)CC(=O)NCc2cccnc2)c1 +Cc1c(Cl)cccc1N(C)S(=O)(=O)c1ccc(N)cc1 +CC(C)(C)NC(=O)N1CCn2nc(-c3ccccc3)nc2C1 +Cc1ccc2nc(SCC(=O)Nc3ccc(F)cc3)nc(=O)n2c1 +Cc1[nH]c2ncnn2c(=O)c1Cc1cccc2ccccc12 +Cc1cc(F)ccc1S(=O)(=O)N1CCCC(C#N)C1 +COc1ccc(-c2nn(CC(=O)N(C)C)c(=O)cc2OC)cc1 +O=C(c1ccco1)N1CCOC2CN(Cc3cccs3)CC21 +CC(C)c1nc(CN(C)C(=O)c2cnn(Cc3ccccc3)c2)no1 +CC(C)(C)C(=O)NCC(=O)NCCc1ccc2c(c1)OCO2 +COc1cc(-c2nc3[nH]cnn3c2Nc2ccccc2)ccc1O +O=S(=O)(CC1CCCCC1)N1CCOCC1C1CC1 +Cc1cccc(-c2cnc(CNCCc3ccccc3Cl)s2)n1 +CCCCS(=O)(=O)NC(C#N)c1cccs1 +CC1CCCCC1N(C)S(=O)(=O)c1cn[nH]c1 +Cc1ccc(=O)n(C(C(=O)Nc2ccccc2N)C(C)C)c1 +CC(C)NC(=O)c1cc(N2CCCC2=O)ccc1Cl +CC(C)Cn1c(SC(C)C#N)nnc1N1CCOCC1 +Cc1ccc(NC(=O)c2ccc(NC(N)=O)cc2)cc1C +CNC(=O)c1sc(Nc2ccc(OC)cc2)nc1C +NC(=O)COC(=O)c1ccccc1NC(=O)c1ccsc1 +CCOCC(=O)N1CCCC1c1cccc(Cl)c1 +O=C(Cc1csc(NC(=O)C2CC2)n1)Nc1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)Cn2cnc(N)n2)c(Br)c1 +c1ccc(CN2CCNC(c3nc4ccccc4[nH]3)C2)cc1 +Cc1csc2c(=O)n(Cc3ccccc3)cnc12 +CCCCN(C)S(=O)(=O)Nc1cccc2[nH]ncc12 +COCC(C)NC(=O)CN(C)S(=O)(=O)c1ccc(C)c(C)c1 +COc1ccccc1CNc1cc(C(=O)N2CCCCC2)nc(C)n1 +COc1ccc2c(c1)c(=O)c(C(=O)Nc1ccc(C)cc1C)cn2C +CCOc1ncccc1C(=O)NCCc1ccc2c(c1)OCCO2 +C=CCCNc1ccccc1CS(=O)(=O)c1ccccc1 +O=C(Nc1ccc(N2CCCC2)nc1)OCC(F)(F)F +O=C(N1CC(O)C1)C1(c2ccc(Cl)cc2)CCC1 +CNS(=O)(=O)c1csc(C(=O)Nc2cn(C)c(=O)cc2C)c1 +O=C(c1cccs1)C1NCCc2cc3cc[nH]c3cc21 +COC1CCCC1NS(=O)(=O)c1cccnc1N +COC(=O)C1CN(Cc2ccc(Br)cc2C)CCO1 +CC(NC(=O)CSc1ncnc2nc[nH]c12)c1ccc(Cl)cc1 +CC(=O)NCCC1CN(Cc2cnn3c(C)cc(C)nc23)CCO1 +CCn1nc(C)c(C(=O)NCC(C)c2ccc(F)cc2)c1C +COc1ccccc1C(C#N)NC(=O)C(C)OCc1ccccc1 +Cn1nc(C(=O)NCc2nc3ccccc3n2C)c(=O)c2ccccc21 +Cc1nn(CCC(=O)NC(C)C2CCCO2)c(C)c1Br +NC(=O)CCc1cc2c(cc1C(=O)Cc1ccccc1)OCCO2 +COC(=O)c1ccc(NC(=O)N(C2CC2)C(C)c2ccco2)cc1C +CC(C)(C)C(=O)CC1(O)C(=O)Nc2ccc(Br)cc21 +CC(C)C1C(=O)NCCN1C(=O)NCC1CCCC1 +CCCn1nnnc1CSc1nc(C)c(C)c(C)c1C(N)=O +CCOc1ccc(C(=O)C2CCCN2C(=O)C(C)(C)C)cc1 +COCCNC(=O)CN1CCN(Cc2ccc3ccccc3n2)CC1 +O=C(CSc1nnc(-c2ccccc2)[nH]1)c1cccs1 +COC(=O)Cn1ccn(-c2ccccc2C)c(=O)c1=O +O=C(c1ccc(-c2ccccc2)cc1)N1CC(c2nc(C3CC3)no2)C1 +Cc1ccc(CC(=O)Nc2cccc(S(N)(=O)=O)c2)s1 +CCOC(=O)C1=C(N)Oc2[nH]nc(C)c2C1c1ccc(SC)cc1 +NC(=O)C1=C(N)Oc2[nH]c(=O)[nH]c(=O)c2C1c1cccs1 +CCOc1ccccc1NC(=O)c1cccc(C)c1N +N#Cc1cccc(OCCSc2nnnn2Cc2cccs2)c1 +COc1ccc(Cc2nnc(NC(=O)C3CCCO3)o2)cc1 +CC(O)CN(C)S(=O)(=O)Cc1ccc(F)cc1F +Cc1cc(Cl)cc(C)c1NC(=O)N(C)CCN1CCCCC1=O +CCc1cccc(C)c1NC(=O)c1ccc2c(c1)OCCO2 +O=C(c1cc(-c2csc(N3CCCC3)n2)c[nH]1)N1CCCC1 +CC(C)CS(=O)(=O)N1CCc2ncncc2C1 +COc1ccc(NC(=O)CCC(=O)c2cccc(OC)c2)cc1 +Cc1cc(COC(=O)Cc2n[nH]c(=O)c3ccccc23)no1 +COc1ccc(C(=O)N(CC2CC2)C(C)C)cc1N +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(C)cc2O)cc1 +CCc1ccc(S(=O)(=O)Nc2ccc(NC(C)=O)cc2)cc1 +CCN(CC)C(=O)CCC(=O)NC1CCC(c2ccccc2)CC1 +COCC(=O)Nc1ccc(C(=O)N2CCCC2)cc1 +CC(=O)N(C)CC(=O)NCc1nncn1-c1ccccc1 +O=C1CCN(C(=O)c2ccc3c(c2)CCC3)CCN1 +CN(C)c1cnc(CC2COCCN(S(C)(=O)=O)C2)cn1 +COc1ccc(CC(=O)N(C)C)c(OC)c1OC +Cc1nc(C(C)(C)NC(=O)c2ccc(CNC(N)=O)cc2)sc1C +O=C(C1CC1)N1CCCN(CC(F)(F)F)CC1 +COC(=O)c1c(C)[nH]c(C(=O)OCC(=O)NC(C)C)c1C +Nc1ccc(O)c(-c2nc3cc(Cl)ccc3o2)c1 +O=C(C1Cc2ccccc2S1)N1CCCC(n2cccn2)C1 +COc1ccc(CNC(=O)Nc2cnccc2C)c(OC)c1 +COc1ccc(CN2CCOC(C)(C)C2)cc1SC +Cc1cc(C(=O)Nc2ccccc2C(=O)NCC(F)(F)F)no1 +O=C(NC1CCCCC1)c1ccc(-n2cnc3ccccc3c2=O)cc1 +N#Cc1cccc(OCc2ccc(Cl)c(N)c2)c1 +CCNC(=O)C(C)NC(=O)Cc1cccc(OC)c1 +CC1CN(C(=O)C2(C)CC2(Cl)Cl)CC(C)O1 +CCOc1ccc(Nc2nc(C)cc(C)c2C(N)=O)cc1 +Cc1ccc(OCC(=O)Nc2ccccc2N2CCCC2=O)cn1 +Cc1occc1-c1nnc(SCc2ncoc2C2CC2)n1C +Cc1nnc2n1CCN(C(C)C(=O)Nc1ccc(Cl)cn1)C2 +CC(C)(C)n1cc(NC(C(N)=O)c2ccc(F)cc2)cn1 +Cc1ccc(C(=O)NCCc2ccc(S(N)(=O)=O)s2)s1 +COc1ccc(-c2n[nH]cc2-c2cnn(-c3ccccc3)c2)c(O)c1 +COc1ccc(C(C)NCc2nccc(N)n2)cc1Br +CC(C)N(C)C(=O)CSc1ccc(Cl)cc1N +CCc1noc(C(C)Sc2ccc3c(c2)OCCCO3)n1 +CC(=O)C(C)CSc1nnc(-c2ccoc2C)n1C +Cc1c(N)c[nH]c(=O)c1C(=O)NC(C)c1ccccc1 +O=C(CCNC(=O)c1ccccc1)NCc1ccccc1Cl +CC(C)Oc1ccc(NC(=O)C(C)CC(N)=O)cc1 +Cc1cccc(NC(=O)NCCc2csc(-n3cccn3)n2)c1 +O=C(c1cccs1)N1CC2CC(C1)c1cccc(=O)n1C2 +Cc1ncc(C(C)NCc2ccc(S(C)(=O)=O)c(C)c2)s1 +O=C(OCc1nc2ccccc2[nH]1)c1cn(-c2ccccc2)nn1 +COc1cccc(C(=O)NCCCN(C)c2ccccc2)c1F +COc1ccc(S(=O)(=O)N(C)CCOc2ccccc2C)cc1 +Cc1cccnc1NC(=O)CCc1c(C)noc1C +CCCn1c(SCc2nnc(C)o2)n[nH]c1=O +O=C(Nc1ccnc2ccnn12)c1ccc(F)c(F)c1 +O=C(Nc1nc(-c2ccoc2)n[nH]1)c1occc1Br +COc1ncccc1NC(=O)NCc1ccc(C)n1C +COC(=O)Cn1c(C(C)NC(=O)c2ccco2)nc2ccccc21 +Cc1cc(Cl)ccc1N(CC(=O)NC(C)(C)C)S(C)(=O)=O +CS(=O)(=O)c1ccc(OCCCSc2ccccc2)cc1 +CCOC(=O)c1c(-c2ccc(Br)cc2)noc1C +CN(C)S(=O)(=O)c1ccc(NC(=O)CCc2ccsc2)cc1 +CCNC(=O)CSc1nc2cc(Cl)ccc2n1CCOC +Cc1cc(C2CCC2)nc(-c2ccccc2CO)n1 +Cc1nnc2ccc(NCCc3ccn(-c4ccc(F)cc4)n3)nn12 +O=C(NCCCc1nnc2ccccn12)c1ccccc1-n1cnnn1 +Cc1oc(C)c(C(=O)NC(C)c2ccccn2)c1C +COc1ccc(C(=O)CSc2ncn(-c3ccccc3)n2)cc1 +Cc1cc(OC(F)F)c(C(=O)NCC(=O)NC2CCCCC2)s1 +Cc1nc(C)c(-c2nnc(NC(=O)Cc3ccc(C)c(C)c3)o2)s1 +CCOCC(=O)NC(C)c1cccc2ccccc12 +COc1cc(OC)cc(-c2nnc3sc(-c4cnn(C)c4)nn23)c1 +Cc1nc(-c2noc3ccc(C(=O)Nc4cccnc4C)cc23)co1 +CC(NC(=O)c1ccccc1)c1ccc(-n2cncn2)cc1 +COC(=O)C1CN(C(C)C)CCN1C(=O)c1cccnc1 +O=C1Nc2cc(Br)ccc2C1NCc1ccc(F)cc1 +CC(C)c1cc(C(=O)C(C#N)c2ccccn2)nn1C(C)(C)C +CCCn1c(N)c(NCC2CCC2)c(=O)n(C)c1=O +CC(=O)NCC1CCCN(C(=O)COc2ccc3ccccc3c2)C1 +CC(C)(C)c1nc(CNCc2cnc(-c3ccccn3)s2)no1 +CC(C)CN1CC(C(=O)Nc2n[nH]c3ccccc23)CC1=O +Cc1ccc(-c2ncco2)cc1NC(=O)NC1CCCC1(C)CO +CCOC(=O)c1cnn(-c2ccnc(-c3ccccc3)n2)c1C(F)F +CC(NC(=O)CCc1cccnc1)c1ccc(Cl)cc1 +CCC(c1ccncc1)N(CC)C(=O)C1CCN(C(=O)N(C)C)CC1 +Cc1ccsc1-c1nnc(CC(=O)NCc2cccnc2)o1 +CCCN(Cc1ccccc1)C(=O)c1ccccn1 +CCOC(=O)Nc1ccccc1Cc1nc(-c2cccnc2)no1 +COC(=O)c1ccc(COc2cccc(F)c2)o1 +COc1ccc(NC(C)=O)cc1NC(=O)NC(C)CCC1CCCC1 +Cc1occc1C(=O)NCC1Cn2nnc(-c3cccnc3)c2CO1 +CCc1ccc(NS(=O)(=O)c2ccc(-c3ccc(=O)[nH]n3)o2)cc1 +CC(Sc1ccccc1Cl)C(=O)NCC1CCOC1 +Nc1ccnn1Cc1cc(Br)cs1 +O=C(NCCN1CCc2ccccc21)c1sccc1Cl +Cc1cc(OC(C)C(=O)Nc2ccccc2C(N)=O)ccc1C(C)C +COc1ccc(OCC(=O)Nc2ccc(C)cc2F)cc1 +Cc1nn(C)c(C)c1OC(=O)c1cnn(CC(C)C)c1C(F)F +CCc1onc(C)c1NC(=O)CC(C)c1ccccc1F +Cc1cc2ccccc2n1CCNC(=O)c1ccc(F)cc1 +Cc1ccsc1CNC(=O)CSc1ccccc1F +C#Cc1cccc(NC(=O)Cc2ccccc2F)c1 +CC(C)COc1ccccc1NC(=O)Cn1c(=O)oc2ccccc21 +COCCn1nc(C(=O)N2CCCC2c2cccc(C)c2)ccc1=O +Cc1cc2c(NCc3ccc(F)cc3)ncnc2s1 +Cc1ccc(Cn2cc(NC(=O)c3cnccn3)cn2)cc1 +CCNC(=O)C1CCN(c2nc3ccc(OC)cc3s2)CC1 +O=C1C(Cc2ccccc2)C(O)C=CN1CCc1cc2ccccc2[nH]1 +Cc1nn(C)c(C)c1C1COCCN1S(=O)(=O)Cc1ccccc1 +COC(=O)Nc1cccc(NCc2nc(-c3ccccc3)no2)c1 +N#CCOc1cccc(CC(=O)N2CCCC2c2ccc[nH]2)c1 +O=C(Nc1ccc(NC(=O)c2ccco2)cc1)Nc1ccccc1F +CNC(=O)C(NC(=O)CN(C)c1ccc(C)cc1C)c1ccccc1 +O=C(Nc1ccc(F)c(F)c1)c1cnc2ccccc2n1 +CCCCCn1cc(O)c(=O)cc1CN1CC(C)OC(C)C1 +Cc1ccc2c(c1)c(CNc1ncc(F)c(N(C)C)n1)nn2C +CC(=O)N1CCCC(C(=O)N2CCCCC2CO)C1 +CCN(CC)C(=O)c1ccc(-c2cccc(OC)c2)nc1N +CCC(=O)Nc1ccc(O)c(C(=O)NCCO)c1 +CC1CN(CC2CCN(c3nc4n[nH]cc4c(=O)[nH]3)CC2)CC(C)O1 +O=C(c1cc2ccccc2oc1=O)N1CCN(Cc2cccnc2)CC1 +CCC(C)C(NC(N)=O)C(=O)N1CCCCCC1 +CNC(=O)C1CCCCN1C(=O)C1CCN(S(C)(=O)=O)CC1 +C=CCNc1nnc(SC(C)C(=O)Nc2cccc(C#N)c2)s1 +Cc1c(NS(=O)(=O)c2ccccc2)cccc1C(=O)NC1CC1 +CC(COCc1ccccc1)C(=O)N1CCC(c2nncn2C)CC1 +CCCCC(=O)N(C)Cc1cc(C#CCCO)cs1 +COc1cccc2c1N(C(=O)c1scnc1C1CC1)CCC2 +CCn1nc(C)c(S(=O)(=O)Nc2ccccc2F)c1C +O=C(CCn1nnc2ccccc2c1=O)Nc1cccc2cnccc12 +Cc1ccccc1C1CC(=O)Oc2c1c(=O)[nH]c1ccccc21 +COCCCNC(=O)CN(C)C(=O)c1ccc(Cl)cc1 +c1csc(-c2n[nH]cc2CNCc2cccnc2-n2cccn2)c1 +NC(=O)c1csc(NC(=O)Cc2ccc(OC(F)(F)F)cc2)n1 +Cc1nc(CNc2ccc(C(=O)NC3CCCC3)cc2C)cs1 +O=C(Nc1ccc(NCCO)nc1)c1ccc(Br)cc1 +COc1ccc(C2COc3cc(OC)ccc3C2=O)cc1 +CCOC(=O)C1CCCCN1c1ccc(C#N)cc1 +O=C(NC1CC1)C1CCCN(C(=O)c2cccc3ccoc23)C1 +CC(=O)Nc1ccc(Nc2ncnc(OC3CCCCC3)c2N)cc1 +CCn1nc(NCc2cc(OC)c(OC)c(OC)c2)cc1C +Cn1ccc(NC(=O)c2cncc(C(=O)Nc3ccn(C)n3)c2)n1 +Cc1ccc(Br)c(S(=O)(=O)NCc2cnn(C)c2)c1 +CCn1c(CNC(=O)c2ccccc2Cl)nc2ccccc21 +O=C(NCc1ccco1)c1scc2c1OCCO2 +COc1ccc(NC(=O)N2CCc3[nH]c(=O)ccc3C2)cc1 +CNC(=O)c1ccc(S(=O)(=O)Nc2cccc(NC(C)=O)c2)cc1 +Cc1noc(C)c1CCC(=O)NC1CCCc2c1cnn2C +CC(=O)NC1CCCN(C(=O)CNC(=O)c2cc(F)cc(F)c2)C1 +COc1cccc(OC)c1COC(=O)C1CC1c1ccco1 +CCOC(=O)c1sc(NC(=O)C2CCCO2)c(C(=O)OC)c1C +CC(CC(=O)Nc1ccc(F)c(Cl)c1)n1ccnc1 +O=C(c1cccc(-c2ncon2)c1)N1CCOCC1c1ccccc1 +Nc1nc(SCc2ccc(F)c(Br)c2)n[nH]1 +CC1COCC(C)N1Cc1cc(F)cc2cccnc12 +COc1ccc(NC(=O)c2cn(C)c3c(OC)cccc3c2=O)cc1 +Cc1nn(C)c(C)c1CCNC(=O)N(C)CCC(F)(F)F +Cc1c(-c2cccs2)nn2c(=O)cc(C3CC(=O)N(C)C3)[nH]c12 +O=C(NC1CCOCC1)C1COC(=O)N1Cc1cccs1 +Cc1nn(C(C)CC(=O)n2nnc3ccccc32)c(C)c1Cl +COc1ccccc1S(=O)(=O)NC(C)(C)CO +COCc1c(C#N)nnn1-c1cccc2c(O)cccc12 +Nc1ccc2c(cnn2-c2ccc(C(F)(F)F)cc2)c1 +CC1(NC(=O)COc2ccc(CC(N)=O)cc2)Cc2ccccc2C1 +Cc1c(C(C)NC(=O)c2c(Br)cnn2C)cnn1C +CCS(=O)(=O)c1cccc(C(=O)NC(C)c2cnn(C(C)C)c2)c1 +CCOC(=O)C1CCN(c2ncnc(NC(C)C)c2N)CC1 +CC(C)(C)c1csc(CCNc2ncnc3[nH]cnc23)n1 +O=C(c1cccc(-n2nnc3cccnc32)c1)N1CCCC1 +CCOC(=O)c1ccc(NCC(=O)N2CCC(C)CC2)cc1 +N#CCc1csc(CCOc2ccccc2Cl)n1 +O=C(C1CCCN(c2nnc3c(Cl)cccn23)C1)N1CCOCC1 +N#Cc1cc(Cn2nnnc2C2CCCC2)ccc1F +CCOC(=O)N(C)c1ccc(NC(=O)c2cnn(CC)c2)cc1 +Cn1cc(N)cc1C(=O)Nc1ccc(C#N)c(Cl)c1 +Cc1cnn(CC(=O)Nc2c(-c3ccc(F)cc3)ncn2C)c1 +Fc1ccc(CSc2nnnn2C2CC2)cc1F +O=C(Nc1cccc(Cl)c1N1CCCCC1)c1cccnc1 +CCCn1nccc1C(=O)NCCCn1ncc2c(Cl)cccc21 +COc1ccc(NC(=O)C(C)Sc2nccn2C)c(OC)c1 +Cc1nc2cc(NC(=O)CCC3Cc4ccccc4NC3=O)ccc2o1 +CC=CCn1c(=O)c2c(nc3oc(C)c(C)n32)n(C)c1=O +CN1C(=O)Cc2cc(NC(=O)C3CCCCC3)ccc21 +NC(=O)C1CCN(C(=O)c2ccc3noc(-c4ccccc4)c3c2)C1 +COc1ccccc1S(=O)(=O)NC(C)Cc1ccco1 +CSc1ccc(NC(=O)c2sccc2NS(C)(=O)=O)cc1 +N#Cc1cccc(NC(=O)c2ccc(O)c(F)c2)c1 +Cc1ccc(S(=O)(=O)NCc2ccnc(OC3CCCC3)c2)cc1 +Cc1cc(NC(=O)NCc2ccnn2C)c2ncccc2c1 +Fc1cccc(NCc2noc(-c3cccs3)n2)c1F +NS(=O)(=O)CCNC(=O)c1sccc1Br +O=C(NC1CCCCC1)c1ccc2ncsc2c1 +CN1CCC(NC(=O)c2ccc(Br)c(F)c2)=NC1=O +CCOc1ccc(C(C)Nc2ccc(NC(C)=O)cc2)cc1 +CC(=O)N1CCC(C(=O)NCCCCN(C)c2ccccc2)CC1 +OCCN1CCN(Cc2nc3cc(F)c(F)cc3[nH]2)CC1 +CCc1cccc(NC(=O)Cn2ccc3c(=O)[nH]ccc32)c1 +CNc1cc(C(=O)N(C)Cc2nc(C)cs2)c2ccccc2n1 +CC(=O)c1c[nH]c(C(=O)Nc2cnn(-c3ccccc3F)c2)c1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)Nc1cccc(Cl)c1 +Cn1c(=O)n(CC(=O)NC(C)(C)c2cccc(F)c2)c2ccccc21 +COC(=O)C(NC(=O)c1ccccc1OC)c1ccccc1 +Cc1ncc(-c2ccccn2)c(C2CCN(C(=O)C3CCCC3)C2)n1 +COc1ccccc1CC(=O)Nc1ccc(F)cc1 +C=CCOc1cccc(NC(=O)Cc2c(C)nc(C)[nH]c2=O)c1 +COc1ccc(Cl)cc1CCNC(=O)CC#N +CC(C#N)C(=O)Nc1ccc(Br)cc1 +C=CCN(C(=O)c1ncn(-c2ccccc2)n1)c1ccccc1 +COc1ccc(C2CC(c3ccccc3)n3ncnc3N2)cc1 +CCOc1cccc(NC(=O)NCc2ccc(OC)cc2OC)c1 +COc1c(Cl)cc(C(=O)N2CCOCC2)cc1Cl +Cc1cccc2c(CC(=O)NCc3ccncc3)c[nH]c12 +Cc1ccc(NC(=O)Cn2cnc3c(cnn3C)c2=O)cc1C +CC(Sc1nnnn1C1CC1)c1nc(Cc2ccc(F)cc2)no1 +NC(=O)CCc1ccc(S(=O)(=O)NC2CC2)cc1 +O=S(=O)(Oc1ccccc1C(F)(F)F)c1c[nH]cn1 +O=C(COc1ccccc1F)NCCn1ccc(-c2ccccn2)n1 +COC(=O)c1[nH]c(C)cc1NC(=O)Cn1nc2n(c1=O)CCCCC2 +CC(C)Oc1ccccc1NC(=O)c1ccccc1CC#N +O=C(Nc1nc(-c2ccc3c(c2)COC3)cs1)C1CCCO1 +Cc1nccn1-c1ccc(F)cc1CNC(=O)c1ccncc1Cl +CCC(C)(C)NC(=O)CSc1nc2ccccc2c(=O)n1C +CCC(NCc1cccnc1)C(=O)c1ccc(N)cc1 +CC(C)OCCS(=O)(=O)NCc1ccncc1 +CC(C)Oc1cc(F)cc(-c2ncccc2C(=O)N(C)C)c1 +CCSc1ccc(C(=O)Nc2cccc(NC(=O)NC)c2)cn1 +CC(C)Oc1ccc(-c2csc(NC(=O)C3CCOCC3)n2)cc1 +COC(=O)c1ccc(NC(=O)CNc2cc(F)ccc2F)cc1 +Cc1noc(COCC(=O)Oc2cc(C(C)C)c(Cl)cc2C)n1 +O=C(CSc1nnnn1-c1ccccc1)N1CCCC1 +CCC1=C(C(=O)OC)C(c2c[nH]c3ccccc23)NC(=O)N1 +CNC(=O)c1ccc(NC(=O)CCc2c(C)n[nH]c2C)cc1 +O=C(NC1CCCCC1)N1CC(CO)CC(CN2CCOCC2)C1 +COCc1nc(C2CCCCCN2C(=O)c2cccnc2OC)no1 +Cc1cccc(NC(=O)c2ccccc2SCC(=O)NC(C)C)n1 +O=C(NCc1ccccc1OC(F)F)c1cc2ccccc2c(=O)[nH]1 +CCOc1ccc(NC(=O)N2CCC3(CC2)OCCO3)cc1Cl +CC(=O)c1ccc(NC(=O)c2sc(C)nc2C)cc1C +Cc1occc1-c1nnc(SCC(=O)N(C)C2CC2)o1 +CC(C)C(C)(C#N)NC(=O)CSc1ccc(F)cc1 +Cc1noc(C)c1C(=O)NCc1ccccc1Cn1cccn1 +CCc1ccc(NC(=O)C(C)c2c(C)n[nH]c2C)cc1 +CCOC(=O)C1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1 +CCC(c1cccs1)n1c(C)nc2cc(N)ccc21 +COc1cccc(CNC(=O)NCCn2c(C)nc3ccccc32)c1 +Cn1ncc2ccc(F)c(-c3ccc(C#N)cc3)c21 +Cc1ccc(-c2nc(CC(=O)Nc3ccc4c(c3)COC4)cs2)o1 +COc1ccc2c(CCNC(=O)Cc3ccccc3)c[nH]c2c1 +CN(C)C(=O)COCC1CN(S(C)(=O)=O)Cc2nnn(C)c21 +Cc1cc(N(C)CC(=O)NC(C)(C)C)nc(-c2ccncc2)n1 +Cc1csc(=O)n1CC(=O)N(Cc1ccccc1)CC1CCC1 +Cc1ccc(OCCNC(=O)CNC(=O)c2cccs2)cc1 +COc1cc(C)ccc1OCC(=O)N1CCOCC1C1CC1 +CCN(C(=O)COc1ccccc1)c1nnc(-c2cccnc2)s1 +Cc1c(C)n2c3c(=O)[nH]c(=O)n(C)c3nc2n1C(C)c1ccccc1 +O=C(CN1CC(c2ccccc2)CC1=O)Nc1ccc(F)cc1 +Nc1ccc(F)cc1C(=O)Nc1cc(F)ccc1F +CC1CCCN(c2ncc(Br)c3cc(N)ccc23)C1 +CS(=O)(=O)c1cccc(OCCn2cc(Cl)c(=O)[nH]c2=O)c1 +COc1ccc(NC(=O)C2(C)CC2(Cl)Cl)cc1OC +Cc1cc(=O)[nH]c2nnc(SCC(=O)NC(C)C)n12 +NS(=O)(=O)c1ccc(NCc2cncnc2)cc1 +O=C(Nc1c(O)cccc1F)c1ccc(-n2cccn2)c(F)c1 +COc1cccc(C(=O)CCC(=O)NCC(C)C)c1 +O=C(NC1CCC2CCCC21)c1ccc2ncccc2c1 +CC(C)(CNC(=O)Cc1cccc(O)c1)c1ccncc1 +COc1ccc(C(=O)CNc2ccc(C(C)=O)cc2)cc1OC +Cc1ccccc1C(O)CNC(=O)CCc1ccsc1 +CCN(CC1CCCO1)C(=O)Nc1ccc(-c2csnn2)cc1 +CCC(=O)Nc1cnn(Cc2cccc(OC)c2)c1 +CN1CCN(S(=O)(=O)c2cccc(OC(F)(F)F)c2)CC1 +CCOC(=O)c1sc(-c2ccc3c(c2)CCO3)nc1C +CCCc1nc(CSc2nnc(C3CC3)n2C2CC2)cs1 +CN(CC(=O)c1cccs1)Cc1cscn1 +O=C(COc1ccc2ccccc2c1CO)N1CCOCC1 +COc1cc(C2NCCc3c(O)cc(O)cc32)ccn1 +O=C1COc2cc(C(=O)N3CCc4cc(F)ccc4C3)ccc2N1 +O=C(OCc1ccccc1)N1CCCC1C=CCn1ccnc1 +Cc1ccc(NC(=O)CSc2nc(N)cc(N)n2)cc1Cl +c1ccc(-c2nccn2CC2CCCO2)c(Cn2cccn2)c1 +N#Cc1cccc(NC(=O)CCSc2ccccn2)c1 +O=C(NCCn1ccc(C(F)(F)F)n1)NC1CCCCC1 +CC(=O)c1cnc(N(C)CCc2noc(C)n2)nc1C +CN(C)C(=O)Cc1ccccc1NC(=O)NCCc1cccs1 +COC(=O)c1c(NC(=O)CC(C)C)sc(C)c1C +CCCc1noc(-c2sc3nnc(C)c(C)c3c2N)n1 +CN(C)c1ncc(CN2CCOC(C(=O)Nc3ccccc3)C2)cn1 +CCN(Cc1cccc(NCc2ccc(NC(C)=O)cc2)c1)C(C)=O +O=S(=O)(Nc1c(F)cccc1F)c1ccc(F)c(F)c1F +CC1Cc2ccccc2N1C(=O)CNc1cccc(F)c1 +O=C(COC(=O)c1ccccn1)c1ccc(Br)cc1 +CCCCc1cc(NC(=O)c2ccc(C(=O)OC)cc2)[nH]n1 +Cc1ccccc1NC(=O)CSc1nnc(C)n1-n1cccc1 +COC(=O)c1cccc(C(=O)NCc2cc3ccccc3[nH]2)n1 +Cc1nn(C(=O)Nc2ccc3c(c2)OCO3)c2ccccc12 +CNc1cc(-c2ccc(S(C)(=O)=O)cc2)nc(C)n1 +CN(C(=O)NCC1(CN2CCOCC2)CCCCC1)C1CC1 +O=C(Cc1cccc(F)c1)NCc1noc(C2CCCCC2)n1 +CC(C)(C)C(=O)C(CO)(Oc1ccc(Cl)cc1)n1cncn1 +COc1ccccc1CNc1cccc(C(=O)NCC(C)C)c1 +Cn1nccc1C(=O)NCC(=O)Nc1ccccc1 +Cn1cc(C(=O)Nc2ccc(Cl)cc2)c(=O)c2ccccc21 +C#CCOC(=O)c1cc(C)n(Cc2ccco2)c1C +O=c1[nH]nc(SCCCOc2ccc(Cl)cc2)n1C1CC1 +O=C1N(c2ccccc2)CCC12CCCN(S(=O)(=O)C1CC1)C2 +Nc1ncnc(SCC(=O)c2ccccc2Cl)n1 +COc1ccc(-c2noc(-c3cc(C)n(C4CC4)c3C)n2)c(OC)c1 +COc1ccc(Br)cc1C(O)C1CCC1 +Cc1nc(C)c(C(=O)Nc2ccc(Br)cc2)s1 +CCCC(=O)N1CCCC1C(=O)NCc1nnc2n1CCCCC2 +Cc1nc(-c2ccc(NC(=O)CCC(C)C)cc2)co1 +COc1cccc(CNS(=O)(=O)c2c[nH]c(-c3nnc(C)o3)c2)c1 +COCc1ccccc1NCc1cc(C#N)ccc1F +CCC(NS(=O)(=O)c1cccc(NC(C)=O)c1)C(C)C +CCOC(=O)CNC(=O)N1CCCC1c1cc(CC)no1 +CNC(=O)Nc1ccc(Oc2ccccc2OC)cc1 +COC(=O)c1ccc(OC(=O)c2cc3cc(F)ccc3nc2C)cc1 +O=S(=O)(Cc1cccc(F)c1)c1ccccc1F +CCc1nc2n(n1)CCCC2NC(=O)CCc1nc(C(C)C)no1 +COCC(=O)Nc1ccc(Oc2ccc(C)cc2)cc1 +O=C(Cn1cncn1)NC1CC2(CCOCC2)Oc2ccccc21 +CCOC(=O)N1CCN(CC(=O)c2ccccc2)CC1 +CCn1ncc(S(=O)(=O)NCc2ccco2)c1N +CN(CC(=O)N1CCNCC1)C(=O)c1cncc(Br)c1 +O=C(c1ccc(Cn2cccc2)cc1)N1CCCC(n2cccn2)C1 +COCc1cccc(CNC(=O)C2CCCCC2)c1 +COC(=O)C(NS(=O)(=O)c1ccccc1Cl)C(C)(C)C +O=C(c1ccc2ncsc2c1)N(Cc1ccccc1)C1CC1 +O=C(Nn1cnc2ccccc2c1=O)c1cc(=O)[nH]c2ccccc12 +CNC(=O)COc1ccc(OC(=O)c2cccc3c2ccn3C)cc1 +COCCOc1ccccc1NC(=O)c1cc2ccccc2n1C +CC1CC(C)CC(CCS(=O)(=O)c2nccn2C)C1 +CC(C)c1ncc(Cl)c(C(=O)NC(C(N)=O)c2ccccc2)n1 +COc1cccc(CN2CCCC(c3nncn3C)C2)c1 +CCOC(=O)C1(O)CCN(C(=O)C2(c3ccc(F)cc3)CCC2)CC1 +CC(=O)Nc1c(C)c(O)c(NC(C)=O)c(C)c1O +CCCNC(=O)C(C)n1nc(C)c(Br)c1C +CC(C)CNC(=O)c1cnc(N2CCCCC2)nc1N +O=C(NCc1cccnc1)C1CC1c1ccccc1C(F)(F)F +CC(=O)c1ccc(OC(=O)COc2ccccc2C#N)cc1 +CC(Cc1ccccc1F)NC(=O)C(C)NC(=O)c1cccs1 +CNC(=O)NCC(=O)NCCC(=O)Nc1ccc(C)cc1Cl +COCCN(CC(C)C)C(=O)c1cc(C(C)(C)C)nn1C +CCS(=O)(=O)NCc1nc2cccnc2n1Cc1cccc(C)c1 +COc1cccc(-c2n[nH]cc2C(=O)NC2c3ccccc3CC2O)c1 +CC(C)CNc1nccc2c(N)c(Br)ccc12 +CCCOc1cccc(C(=O)Nc2ccccc2C(=O)NCC)c1 +Cc1cnn(CCC(=O)Nc2cccc(-n3nccc3C)c2)c1 +COC(=O)c1cc(-c2cc(O)cc(F)c2)cs1 +COc1ccc(C(NC(=O)NCC(C)CO)C(C)C)cc1 +NS(=O)(=O)c1ccc(OCCOC(=O)c2ccc(F)cc2)cc1 +C=CCNC(=O)Cn1c(=O)c2c(OCC)c(C)cnc2n(C)c1=O +COc1cccc(C(O)C(=O)N2CCNCC2)c1 +CCC(C(=O)NCc1ccsc1)c1ccccc1 +Cc1cc(C)n(-c2ccc(NC(=O)CN3CCCC3=O)cn2)n1 +Cc1ccc(C)c(NC(=O)c2cc(-n3ccnc3C)ccn2)c1 +CCOC(=O)CSc1nc2c(c(=O)n(CC)c(=O)n2C)n1C +CC(C)NC(=O)c1cccc(-c2ccc(N3CCOCC3)nn2)c1 +COCCCNC(=O)c1cnn(-c2ccncc2)c1C +N#CCCN(CCN1CCOCC1)S(=O)(=O)c1cccs1 +COc1ccc(NC(C)=O)c(NC(=O)c2cc(C)ccc2C)c1 +Cc1csc(=O)n1CC(=O)N(Cc1ccccc1)c1ccccc1 +Cc1cnn(CCC(=O)NCC2CCCc3ccccc32)c1 +Cc1ccc(NC(=O)C(N)c2ccccc2)c(Br)c1 +O=C(c1ccc(OC(F)F)cc1)N1CCc2cc(F)ccc2C1 +Cc1c(NC(=O)C(C)NC(=O)Nc2ccccc2)cccc1C(N)=O +O=C(CCc1cccc(Br)c1)NC1CCC(O)CC1 +Cc1cc(NC(=O)CCNC(=O)C2CC2C)[nH]n1 +CCc1nc2cc(C(F)(F)F)ccc2n1CCCO +CC(C)(C)C(=O)Cn1nc(C2CC2)cc(C(F)(F)F)c1=O +Cc1c(C(C)NC(=O)NCc2cnn(C)c2)cnn1C +CNC(=O)c1ccc(CNc2cc(Br)ccc2OC)cc1 +CCOC(=O)c1c(C)oc2nc(C)nc(NCCC3=CCCCC3)c12 +COc1cc(C(C)=O)ccc1OCc1csc(C)n1 +CCc1onc(C)c1NC(=O)c1ccc(Cl)cc1N1CCCC1=O +CCOc1ccc(NC(=O)c2cc(C)nn2C)c(C)c1 +CC(=O)c1cccc(NC(=O)C2CCCN(C(N)=O)C2)c1 +O=S(=O)(c1ccc(CN(CCO)c2ccccc2)cc1)C(F)F +CN(C)c1ncc(Br)c2ccc(N)cc12 +Cc1nn(C)c(=O)c2c1cnn2-c1ccc(F)cc1 +CC(=O)Nc1ccc(NCC(=O)Nc2cccc3ccccc23)cc1 +CN(Cc1ccnn1C)C(=O)Nc1cccc(Cl)c1Cl +CCOC(=O)c1cccc2[nH]c(=O)n(C(C)(C)CO)c12 +N#Cc1ccccc1C(=O)N1CCCCC1c1cccc(F)c1 +CCC1Oc2c(OC)cc(CO)cc2N(CCC(C)C)C1=O +CCc1c(C(=O)Nc2ccc(C(C)=O)cc2)nnn1-c1ccccc1 +COc1ccc(C(=O)N2CCC(O)(C(F)(F)F)C2)cc1OC +Cc1nc2ncnn2c2ccn(-c3ccc(F)cc3F)c(=O)c12 +O=C(NCCOc1ccc(F)cc1)NCC1CC1 +CCS(=O)(=O)c1ccc(N2CCc3ccccc32)cc1N +CC(c1ccccc1)N(C)C(=O)Cn1c(=O)oc2ccccc21 +CC(=O)NCCNC(=O)c1cn(C)nc1-c1ccc(F)cc1F +CCn1nnnc1SC(C)C(=O)Nc1cccc(F)c1 +NC(=O)c1ccc(CNCCc2ccc(F)cc2)cc1 +CCNC(=O)c1ccc(Cl)cc1NC(=O)COC +O=C(COC(=O)Cc1cccs1)Nc1ccc(F)c(F)c1F +CCCCC(=O)Nc1nnc(-c2ccc(OCC)cc2)o1 +O=C(Nc1cc(-c2ccccc2Br)n[nH]1)c1cnccn1 +O=C(Cc1ccc(F)cc1)N1CCC(c2n[nH]c3nccnc23)CC1 +CCOc1ccc(SCC(=O)C(C#N)c2nc(C)cc(C)n2)cc1 +CCCC(=O)NCCc1ccc(OC(F)F)cc1 +O=C(NC1CCCc2occc21)c1ccc(Oc2ccccc2)nc1 +COc1nccnc1N1CCC(N(C)S(=O)(=O)c2ccccc2)C1 +CC(=O)N1CCN(S(=O)(=O)c2c(C)c(C)cc(C)c2C)CC1 +COCCOCC(=O)Nc1cccc(C#Cc2ccccn2)c1 +N#Cc1ccc(-n2c(-c3ccncc3)nc3ccccc32)cc1 +CCOC(=O)c1sc(NC(=O)c2cnccn2)c(C#N)c1C +CC1(CCNC(=O)Nc2cc(-n3cccc3)ccc2F)OCCO1 +Cc1cnc(-c2cccc(NS(=O)(=O)N(C)C(C)C)c2)o1 +Cc1cccnc1NC(=O)c1ccc2c(c1)NC(=O)C(C)S2 +COC(=O)c1cccc(NC(=O)c2nc3nc(C)cc(C)n3n2)c1 +CC(CC(=O)Nc1cccc(Cl)c1)n1cccn1 +N#Cc1ccccc1NC(=O)c1cccc2c1SCCC2=O +CCc1nc(NC2CCCC2)c(N)c(OCCOC)n1 +Cc1nc(C)n(CC(=O)NCCc2ccccc2C)n1 +COc1cc(OC)c(C(=O)OCc2scnc2C)cc1OC +COC(=O)c1ccc(CN2CCOC(C3CCCO3)C2)o1 +CCNC(=O)CN(CC)S(=O)(=O)c1cn[nH]c1C +CCc1c(C)sc2ncn3nc(-c4c(Cl)c(C)nn4C)nc3c12 +COc1cc(OC)c(NC(=O)NC(C)c2ccc(C)o2)cc1F +COc1cc(OC)cc(C(=O)Nc2ccnc(C)c2)c1 +CN(Cc1ccc(Cl)cc1)C(=O)c1ccncc1 +Cc1ccc(OC2CCCCC2N2CCOCC2)c(N)c1 +CC(=O)Nc1cccc(Nc2ccc(Cl)cc2N)c1 +CCOC(=O)C(C)NC(=O)c1cc(F)ccc1N +COCc1nc(C)c(C(=O)N2CCCc3c(F)ccc(C)c32)s1 +CC(=O)N1CCCN(C(=O)Cn2nc(C)c(Cl)c2C)CC1 +COc1cccc(NC(=O)Cn2cc(C)c(N)n2)c1 +CC1=NC(CN(C)Cc2sc(C)nc2C)N=C1 +CC(=O)Nc1cccc(NC2CCC3(CC2)OCCO3)c1 +O=C(NCCNC(=O)c1ccccn1)c1ccccn1 +CCCNC(=O)c1nc(CCS(=O)(=O)c2ccc(F)cc2)no1 +Cn1nc(C(=O)NCCOc2cccc(C(C)(C)C)c2)ccc1=O +C=CCn1c(N)c(C(=O)NC2CCCC2)c2nc3ccccc3nc21 +C=CCn1c(C)nnc1SCC(=O)c1c(C)cc(C)cc1C +CC(=O)c1cccc(NS(=O)(=O)c2ccc(CO)cc2)c1 +CC(C)(C)c1cc(NS(=O)(=O)Cc2ccccc2)no1 +O=C(CNS(=O)(=O)c1ccc(Cl)cc1)N1CCOCC1 +COc1ccc(OC)c(CC(=O)Nc2nnc(C(C)C)s2)c1 +CCCn1nnc(NC(=O)c2ccc(C#N)cc2F)n1 +O=C(NCC(O)c1ccc(O)cc1)c1cnc(-c2cccnc2)nc1 +Cc1nc(C)c(CC(=O)NC2(C)CCC(C)CC2)c(=O)[nH]1 +O=C(NCc1ncccc1F)c1cc(F)cc(Cl)c1O +Cc1cccc(OCC(=O)c2c(C)[nH]c3ccc(F)cc23)c1 +Cc1ccc(S(=O)(=O)NCc2cnn(C)c2)c(C)c1 +Cc1ccccc1SCC(=O)c1c(N)n(C2CC2)c(=O)[nH]c1=O +Cc1ccc(OC(=O)CCCCNC(N)=O)cc1C +O=C(NCc1ccco1)Nc1cccc(Cl)c1-n1cccn1 +Cc1ccncc1NC(=O)NCc1ccc(C(N)=O)o1 +Cc1nn(C)c(C)c1OCC(=O)N(C)c1ccccc1 +CSc1ccc(CN(C)C(=O)c2ccc(F)cc2)cc1 +Cc1ccc(C(C)NC(=O)c2cc3c(F)cccc3[nH]2)o1 +Nc1ccc2sc(C(=O)NC3CCCCC3)nc2c1 +CCCCOc1cccc(-c2nc(N)nc(C)c2C(=O)NCC)c1 +CCC1CN(S(=O)(=O)c2cn[nH]c2C)CCO1 +CCCC1CN(C(=O)C2CC2c2cccc(F)c2F)CCO1 +COc1ccc(OC)c2sc(NCCN3CCOCC3)nc12 +C=CCOc1ccc(C(=O)NCCN2CCN(C(C)=O)CC2)cc1 +Cc1ccc2ncc(C(=O)NC(C#N)c3ccc(F)cc3F)n2c1 +CCN(CC(C)C#N)C(=O)CCNC(=O)c1ccoc1 +CC(C)(C)c1cc(NC(=O)NCCCCn2ccccc2=O)no1 +c1ccc(COC2COC3(CCN(c4cncnc4)CC3)C2)cc1 +Cc1ccc(NC(=O)NCCNC(=O)c2ccc(C)c(F)c2)cc1F +Cn1ncc2c(N3CCN(C(=O)Cc4cccs4)CC3)ncnc21 +COC(=O)C1C(c2ccc(C)cc2)c2c(O)n[nH]c2CC1(C)O +CCOCC(=O)Nc1c(C)cc(Br)cc1C +Cc1cc(NC(=O)CN2CCOCC2c2cccn2C)n(C)n1 +Cc1cc(NC(=O)C(OC(=O)c2n[nH]c3ccccc23)C(C)C)no1 +Nc1c(-c2cccnc2)nnn1-c1ccc2c(c1)OCO2 +COC(=O)c1sc(NC(=O)Cc2cccc(OC)c2)nc1C1CC1 +Cc1ccc(CC(=O)NCc2sccc2C)s1 +COc1ccc(-c2cc(C(=O)NC3CC3)ccn2)cc1Cl +CN1C(=O)CCCC12CCCN(C(=O)CCc1ccccc1)C2 +CC(Nc1ncnc2ccc(F)cc12)c1ccc(F)cc1F +COc1ccc(C(O)CNC(=O)c2ccc(CNC(N)=O)cc2)cc1 +CC(=O)c1c(SCC(=O)Nc2ccc(C)cc2C)nc(=O)[nH]c1C +Cc1ccc(S(=O)(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1 +Cc1nc2cc(NC(=O)c3nnn(-c4ccccc4)n3)ccc2s1 +COCCS(=O)(=O)N(C)C(C)c1ccc(O)cc1 +CCc1onc(C)c1NC(=O)c1cc2c(s1)CCOC2 +CN(C(=O)c1cc2cc(C(F)(F)F)ccc2n1C)c1ccnn1C +O=S(=O)(NCCc1ccccn1)c1c(F)cccc1F +CC(C)CCn1nnc(CO)c1-c1ccccc1Cl +CCCn1nc(C)c2c(C(=O)OC)cc(-c3cnn(C)c3C)nc21 +Cc1nnc(SCC(=O)NCc2ccccc2)n1C(C)C +COc1cc(C(=O)N2CCCC2)cc(Cl)c1OCCC(C)C +CC(C)(C)OC(=O)c1cc(Br)ccn1 +N#CCOc1ccc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)cc1 +Cc1ccc(NC(=O)c2c[nH]c(=O)n(-c3ccc(C)c(C)c3)c2=O)cc1 +CCN(Cc1ccccc1)C(=O)c1cn2ccccc2n1 +O=c1c2cnc3ncnn3c2ccn1Nc1nc2ccccc2[nH]1 +COC(=O)CCNC(=O)c1ccc(NC(=O)c2ccc(C)cc2)cc1 +Cc1noc(NC(=O)CCCc2c[nH]c3ccccc23)n1 +COc1ccc(F)cc1NC(=O)CN1C(=O)CCc2ccccc21 +COC(=O)c1c(OC(C)=O)c2ccccc2n1C(C)=O +CCN(Cc1ccc(OC)c(F)c1)C(=O)c1ccc2[nH]nnc2c1 +Nc1ccc(NC(=O)c2nn(-c3ccc(F)cc3)c3c2CCC3)cn1 +CC(=Cc1nc(-c2ccc(C#N)cn2)no1)c1ccc(F)cc1F +CCCn1nc(C(=O)N2CCCCC2Cn2cccn2)ccc1=O +CCn1c(-c2cc(NC(C)=O)[nH]n2)cc2ccc(OC)cc21 +CC(C(=O)N1CCN(Cc2ccco2)CC1)n1cccn1 +Cc1nc(C)c(CC(=O)NCCCN(C)c2ccccc2)c(=O)[nH]1 +CC(C)c1cccc(S(=O)(=O)NCCOC(N)=O)c1 +Cc1cccc(C2(C(=O)Nc3ccncc3)CC2)c1 +O=C(CCC1CCCCC1)N1CCC(Oc2cccnc2)CC1 +CCOC(=O)C(O)Cc1ncc(-c2ccncc2)o1 +CC(C)C(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +NC(=O)c1ccccc1NC(=O)CCCc1ccc2c(c1)CC(=O)N2 +O=C(NCC1CCOC1)c1cc(-c2cccnc2)on1 +CNC(=O)NCC(=O)NC(C)(C)c1ccc(Cl)c(Cl)c1 +O=C(NCc1cn2c(n1)SCC2)c1nc2ccccn2c1F +Cc1nc(-c2ccsc2)sc1C(=O)N1CCCS1(=O)=O +Cc1ccc(NC(=O)CSc2nccc(=O)[nH]2)c(C)c1 +CCOC(=O)C1CCCN(c2ncnc(Oc3cccnc3)c2N)C1 +CCCS(=O)(=O)N1CCc2ccc(Cl)cc2C1 +O=C(CNC(=O)c1ccc(-c2ccccc2)cc1)NCc1ccncc1 +COc1ccc(NC(=O)c2cccnc2OCC(F)F)c(OC)c1 +COc1ccc2c(c1Br)C(CN(C)C)NCC2 +COc1cccc(OCC(=O)N(C)C(C)c2ccc(F)cc2)c1 +Cc1ccc(-c2cncc(C(=O)NCc3cccnc3)c2)cc1 +CCOC(C)c1nc(COc2cc(C)c(C)nn2)cs1 +CCc1nccc(CN(C)CC2COc3ccccc3O2)n1 +COCCNC(=O)C(C)S(=O)(=O)c1cccc(C)c1 +O=C(Oc1cccc2[nH]c(=O)ccc12)c1ccccc1 +Cc1c(Cl)c(C(F)(F)F)nn1CC(=O)N(C)Cc1ccccc1 +CC(C)CN(C(=O)CSc1ncn(-c2ccccc2)n1)C1CC1 +CCc1cnc(C)nc1NCc1n[nH]c2c1CCC2 +CN(CC(=O)N(C)C1CC1)C(c1ccccc1)C(F)(F)F +Cc1noc(COC(=O)Cn2c(=O)[nH]c3ccccc32)n1 +CC1CC(C)CN(c2ncc(N)cc2Br)C1 +CCCC1CN(C(=O)CNC(=O)NCc2ccco2)CCO1 +CS(=O)c1ccc(C(=O)NCCNC(=O)C2CC2)cc1 +COc1ccccc1C(NC(=O)Cc1ccc[nH]1)c1noc(C)n1 +CCC(=O)Nc1cc(S(=O)(=O)N(C)C(C)C)ccc1C +Cc1ccc(CNC(=O)CSc2nnc(C3CC3)n2C)cc1 +CSc1nc2sc3c(c2c2nnc(C)n12)CC(C)(C)OC3 +COC(=O)c1ccc2nc(C)cc(NC(=O)c3ccco3)c2c1 +Cc1ccc(CNC(=O)Nc2ccc(C(N)=O)cc2F)c(N(C)C)c1 +COC(=O)c1ccc(NC(=O)c2c[nH]c3c(F)cccc3c2=O)cc1 +c1ccc(COc2ccc(CSc3ncnc4nc[nH]c34)cc2)nc1 +CCc1ccc(NC(=O)CCS(=O)(=O)N2CCNCC2)cc1 +CCc1noc(CC)c1CNC(=O)Nc1cnccc1C +O=C(NCc1ccncc1)C(Cc1ccccc1)n1cnnn1 +COC1CCN(S(=O)(=O)c2ccccc2C(C)(C)C)CC1 +CCCCNC(=O)CNc1c(C)cccc1C(N)=O +CC(C)(C)c1nnc(NC(=O)NCc2nnc3ccccn23)s1 +COc1ccc(OC)c(C(O)CNC(=O)c2cccs2)c1 +COCCn1cc(NC(=O)NC2(CO)CC(C)CC(C)(C)C2)cn1 +O=C(Nc1cc(-c2nc3cnccc3o2)ccc1Cl)c1ccco1 +COc1ccc2c(-c3cc(-c4ccn(C)c4)nc(N)c3C#N)n[nH]c2c1 +Cc1cc(C(=O)Nc2ccccc2C(F)(F)F)c(C)o1 +CC(=O)Nc1ccc(NC(C(N)=O)c2ccccc2)cc1C +C=CCn1c(N2CCC(C(=O)NC3CC3)CC2)nc2ccccc21 +CCc1ccc2c(c1N)C(C)(C)S(=O)(=O)N2C +COC1CCCC1OC(=O)CCc1c(C)nn(C)c1C +Cn1cc(CC2CCN(C(=O)Cc3c(F)cccc3F)C2)cn1 +CCCNc1cc(S(=O)(=O)N(C)CC)ccn1 +O=C(c1cncc(Br)c1)N1CCSc2ccccc21 +Cc1ccsc1C(=O)OCc1ccc(C#N)cc1 +O=C(NCCC(=O)N1CCc2ncccc2C1)NC1CCCCC1 +O=C(COc1ccc(F)c(F)c1)Nc1ccccc1 +CC1(C)CN(CCN2CCOCC2)c2cc(N)ccc2O1 +OC(CN(Cc1ccco1)C1CC1)c1ccccc1 +COc1cccc(CC(=O)NCc2ccc(-n3ccnc3)cc2)c1 +Cc1cc(-c2nnc(SCC3CC3(Cl)Cl)o2)no1 +Cc1cnc(NC(=O)C(C)Oc2cccc(F)c2)s1 +CCOC(=O)C1=C(C)NC(=O)NC1c1ccoc1 +COc1cccc(-c2cc(C(=O)NCc3ccccn3)n[nH]2)c1 +Nc1cccc(OCCNc2ccccc2C(F)(F)F)c1 +COc1ccccc1NC(=O)c1ccc(-n2cccn2)cc1 +Cn1ccnc1C(=O)c1ccc(NC(=O)C2CC=CCC2)cc1 +CCC(C(=O)NCc1ccco1)n1nnc(-c2ccc(Cl)cc2)n1 +C=CCNC(=O)C(C)Sc1nc(C2CC2)nc2ccccc12 +CCOc1ccc(C(=O)CCC(=O)Nc2nnc3n2CCCC3)cc1 +CC(C)(C)n1nnnc1C(c1ccncc1)N1CCCCCC1 +CC(=O)N1CCc2cc(NC(=O)CCc3ccccc3Cl)ccc21 +CNC(=O)NCC(=O)N1CCC(c2c[nH]c3ncccc23)CC1 +Cc1cc(C(=O)N2CCC(Cc3ccccc3)C2)no1 +O=C(CCn1ccnn1)NCC(O)c1ccccc1 +CCC(O)c1c(-c2cccs2)nc2cccc(C)n12 +CCNC(=O)Nc1ccccc1CN(CC)C(C)=O +Cc1occc1C(=O)OCc1coc(-c2ccccc2)n1 +c1ccc(OCC2CC3OCCN(Cc4ccsc4)C3C2)nc1 +C=CCOc1ccc(-c2nonc2NC(=O)CC)cc1 +Cc1ccc(-c2nc(CNS(=O)(=O)c3cnn(C)c3)co2)cc1 +CC(=O)Nc1cccc(-c2cc(C#N)nn2C(C)C)c1 +CCc1cccc2c1N(C(=O)Cc1ccc(-n3cnnn3)cc1)CCC2 +COc1ccc(CN2CCOC3CCCCC32)cc1SC +CC(CC#N)N(C)C(=O)CCc1ccc(OC(F)(F)F)cc1 +O=C(Nc1ccccn1)C1CCCN(C(=O)NCc2cccs2)C1 +COC(=O)Cc1csc(NC(=O)c2ccc(-n3ccnn3)cc2)n1 +OC(c1ccco1)c1ccccc1OC(F)(F)F +Cc1cc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)no1 +CCS(=O)(=O)N1CCN(C(=O)c2ccccc2)CC1 +CCC1CCCCN1C(=O)C(C)c1c(C)nn(C)c1C +CCC(CC(=O)Nc1ccnc(C(=O)N(C)C)c1)c1ccccc1 +Cc1nc2cc(NC(=O)Cn3ccc(C(F)(F)F)n3)ccc2o1 +Cc1cc(C(=O)NCc2nc3ccccc3[nH]2)c2ccccc2n1 +COc1ccccc1C(=O)N1CCN(C(=O)Cc2cccnc2)CC1 +N#Cc1ccc(OCC(=O)NCCOc2ccccc2F)cc1 +CC(NC(=O)c1cccnc1OCC(F)F)c1ccc(F)c(F)c1 +N#Cc1ccc(NC(=O)CS(=O)(=O)c2ccccc2)cc1Cl +O=C1CCCN1CCCSc1ccc2c(c1)OCCCO2 +CCSc1ccccc1C(=O)N1CCC(C)CC1 +CNC(=O)c1nsc(C(=O)NCc2cccc(OC)c2)c1N +COc1cc(C2(C(=O)NCc3nc(C)sc3C)CC2)ccc1C +CCCn1cc(C(=O)Nc2cccc(C)c2C)c(=O)c2ccc(C)nc21 +O=C(Nc1cccc(Cl)c1Cl)c1ccccn1 +O=C(NCCc1ccn(-c2ccccc2)n1)c1ccc2c(c1)OCCO2 +C#CCN1CCN(C(=O)NCCCN(C)c2ccccc2)CC1 +Cn1cnnc1C(=O)Nc1cccc(C(F)(F)F)c1 +CC(C)N(Cc1cc2c(s1)CCC2)C(=O)CNC(=O)NC1CC1 +C=CCn1c(=O)[nH]c2cc(C(=O)NC3CCCC3)ccc2c1=O +Cc1cc(C(=O)NC(C)C)ccc1NC(=O)Cc1cccc(F)c1F +N#Cc1ccccc1C(=O)c1ccc2c(c1)OCCO2 +O=C(CCCn1cc(Cl)cn1)c1ccc(F)cc1 +Cc1nc(C)c(C(=O)N2CCC3(CC2)OCCO3)s1 +CCCc1ccc(CCCC(=O)N2CCC(=O)CC2)cc1 +CC(C)(C)OC(=O)N1CCCN(C(=O)c2cnccn2)CC1 +Cc1cc2cc(CNC(=O)CC(C)(C)C)ccc2[nH]1 +CCOC(=O)c1sc(NC(=O)c2ccc(Cl)cc2F)nc1C +Cc1cccc(C(N)C(=O)NCC(O)CO)c1C +CCCNC(=O)C(C)NC(=O)Nc1c(C)cccc1C +CC1C(O)c2ccccc2C2c3ccccc3C(=O)N21 +COC(=O)c1c(C)nn2c1ncc1c(=O)n(CCC(C)C)ccc12 +CC(C)C(NC(=O)C1CC(=O)N(Cc2ccco2)C1)c1cccs1 +CC(=O)c1cccc(Nc2ncnc(NCc3ccc(C)cc3)c2N)c1 +COCc1cc(NC(CO)c2ccccc2)n2ncnc2n1 +Cc1ccc(NC(=O)NCc2ncn(C)n2)cc1OCCC(C)C +CC(C)C(Cc1ccc(F)cc1)NC(=O)NCc1ncn(C)n1 +O=C(NCCc1ccccc1)N1CCC(Oc2cccnc2)CC1 +COc1ccc(-n2nc3cc(C)c(N)c(Br)c3n2)cc1 +CCC1CN(C(=O)c2cccnc2N2CCOCC2)CCC1(C)O +COc1cccc(CNC(=O)Nc2cc(NC(C)=O)ccc2C)c1 +O=C(Nc1ccccc1C(=O)NC1CC1)c1ccc(-n2cncn2)cc1 +CCS(=O)(=O)N(Cc1noc(C2CC2)n1)c1ccc(C(C)=O)cc1 +CCCC(=O)N1CCc2sccc2C1C(=O)OC +CCCn1nc(-c2ccccc2)cc(C(C)=O)c1=O +O=C(Cn1nc(-c2cccs2)n(C2CC2)c1=O)N1CCOCC1 +CS(=O)(=O)N1CCC2(CCCN2c2nncs2)CC1 +CN(CCN1CCOCC1)C(=O)NC1CCCOc2ccccc21 +CC(C#N)NC(=O)c1ccc(-n2cnc3ccccc32)nc1 +COc1ccc(C(=O)Nc2ncccc2O)cc1F +CCOc1ccccc1NC(=O)Nc1ccc(N(C)C(C)=O)cc1 +CC(=O)c1cc(C(=O)NC(C)(C)c2ccc3c(c2)OCCO3)n(C)c1 +Cc1cccc(CCNC(=O)c2ccc(S(=O)C(C)C)cc2)c1 +CCc1ccc(CNS(=O)(=O)c2ccccc2F)s1 +COc1cccc(OC)c1-c1nc2c([nH]1)CCCNC2=O +Cc1cnc(NC(=O)C2CN(C(=O)c3cccs3)C2)s1 +CCc1ccccc1NC(=O)c1c[nH]c2c(Cl)cccc2c1=O +COC(=O)C1CCC(NC(=O)c2ccc3c(c2)N(C)CC3)CC1 +CCC(C)(C)NC(=O)C(C)N1CCSc2ccc(N)cc21 +CC(C(=O)N1CCc2ccccc21)n1nnc(-c2ccccc2)n1 +O=C(CCN1Cc2ccccc2C1=O)NCc1cnn2ccccc12 +CN(CC1CCCO1)C(=O)NCc1cccc(N2CCCCC2=O)c1 +COc1cc(C(=O)Nc2ccccc2C(=O)NC(C)C)ccc1C +CCOCCNC(=O)COc1ccc(Br)cc1Cl +Cn1c(=O)c2c(-c3ccccc3)n(CC3CCCO3)cc2n(C)c1=O +Cn1ccc(-c2nnc(NC(=O)NCc3cccc4ccccc34)o2)n1 +CCn1cc(CN(C)C(=O)c2nn(C)c(C)c2Cl)cn1 +COc1cccc(NC(=O)c2nc3c(s2)CCN(C(C)=O)CC3)c1 +O=C(CCSc1nnc(C2CCCCC2)o1)Nc1cccc(F)c1 +COCc1cc(=O)[nH]c(Nc2ccc(OC)c(Cl)c2)n1 +CC(C)CNC(=O)c1cc2cnn(C(C)C)c2nc1N +CC(=O)NCC1CCCN(C(=O)c2csnn2)C1 +CC(CC(=O)NCc1ccc(Cl)cc1)n1cccn1 +CCNC(=O)c1ccc(C)c(NCc2noc(-c3ccoc3)n2)c1 +COc1ccc(CC(=O)N(CCC#N)C(C)C2CC2)cc1 +Cc1cc(C2CCCN(C(=O)CCc3nc(C(C)(C)C)no3)C2)n[nH]1 +COCc1nnc(NC(=O)CNc2cc(C)cc(C)c2)s1 +CCCNC(=O)CNC(=O)NCc1ccc(C)cc1 +CCNC(CC(=O)OC)C(=O)c1ccc2c(c1)ncn2C +CC1(C(=O)Nc2ccc(-n3cccn3)nc2)CC1(Cl)Cl +COc1ccnc(NCc2c(C)cc(C)[nH]c2=O)n1 +CCn1nc(C)c(CNC(=O)Nc2cccc(C(=O)OC)c2)c1C +COCc1ccc(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)o1 +O=C(COc1nnc2ccccn12)NCCc1c(F)cccc1F +CN(C)C(=O)CN1C(=O)C2CCC1CN(C(=O)c1cnccn1)C2 +Brc1cncc(-c2nn3c(C4CC4)nnc3s2)c1 +Cc1ccc2nc(-c3ccc(C(=O)N4CCOCC4)cc3)[nH]c(=O)c2c1 +CN(CC1COc2ccccc2O1)c1ccc2nncn2n1 +CCc1noc(CC)c1CC(=O)Nc1ccc(C(=O)OC)c(C)c1 +N#Cc1cccc(CSc2nnc(-c3ccccc3)c(=O)n2N)c1 +CCOCC1CC2(COCCN2S(=O)(=O)c2cccs2)CO1 +Cc1nnc(CNC(=O)C2CSc3ncc(C)c(=O)n3C2)o1 +Cc1cc(C)cc(NC(=O)C(c2ccccc2)N2CCOCC2)c1 +NC(=O)CCCNC(=O)c1ccc(Oc2ccc(F)c(F)c2)cc1 +O=C(Cc1n[nH]c2c(Cl)cccc12)NCC(=O)N1CCCC1 +Cc1cccc2nc3c(c(=O)n12)CN(C(=O)c1ccco1)CC3 +N#Cc1ccc(NCC(=O)N(Cc2ccccc2)C2CC2)cc1 +CCN(CC)S(=O)(=O)c1ccc(N(C)CC(=O)NC)nc1 +COc1ccc(NC(=O)CN2CCN(c3ccccc3F)C2=O)cn1 +Cc1cccc(-c2nnn3c2COC(CNCc2nccs2)C3)c1 +CC(C)CC1COCCN1C(=O)C(C)OCc1ccccc1 +Cc1cccc(NC(=O)NCc2ccccc2OC(F)F)n1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)C(=O)c1cc(F)ccc1C +Cc1cc(NC(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)no1 +COc1ccc(C(O)CCN2CC(C)OC(C)C2)cc1C +Cc1ccc2nc3c(cc(C(=O)NCc4cccnc4)n3C)c(=O)n2c1 +c1coc(-c2nc3cnccn3c2NC2CCCC2)c1 +CC(C)(C)c1ccc(C(=O)Nc2ccccc2F)c(N)n1 +O=C(CSc1nc(=O)[nH]c2c1CCC2)Nc1cccc(Cl)c1 +O=C(NCCN1CCOCC1)Nc1cccc(C#Cc2ccccc2)c1 +O=c1c2ccccc2nnn1CC(O)COCc1ccc(Cl)cc1 +CCn1c(COc2cc(C)ccc2Cl)nnc1SCC(N)=O +Cc1cccc(C)c1OCC(=O)NCc1ccc2c(c1)OCCO2 +Cc1ncsc1C(=O)C(C#N)c1nc2cc(F)ccc2s1 +CN(Cc1ccccn1)C(=O)NCc1ccc(O)cc1 +COC(=O)COc1cc(Br)c(CO)cc1OC +CC(=O)Nc1cccc(C(=O)N(C)c2ccccc2)c1 +CCCN1C(=O)C2CCC1CN(C(=O)NCc1ccc(OC)cc1)C2 +Cc1cc(C(=O)NC2CCCCC2)ccc1NCC(=O)N(C)C +CCc1cc(C(=O)N2CCCC2C(=O)N(C)C)[nH]n1 +COc1ccc(CN(C)C(=O)CCC#N)cc1C(C)C +O=C(Cc1cccc(F)c1)N1CCc2ncnc(NC3CC3)c2CC1 +CCNc1cncc(S(=O)(=O)NCc2ccccc2OC)c1 +COc1ccccc1CCc1nc(C)nc(CN)n1 +Cc1cc(C(=O)NC(C)c2ccc(Br)cc2)no1 +NC(=O)c1ccc(CNC(=O)c2cccc(-c3ccoc3)c2)o1 +Cc1ccc(S(=O)(=O)NCC2CCCC2O)c(F)c1 +CC(C)CC(=O)Nc1cccc(-c2nn3cnnc3s2)c1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)Nc1cccnc1 +NC(=O)CCCCn1ncc(Cl)c(Cl)c1=O +Cc1noc(C)c1CN1CCN(C(=O)Nc2ccccc2F)CC1 +COC(=O)C(Cc1ccc(F)cc1)NC(=O)C1CC=CC1 +COc1ccc(F)cc1C(=O)NC1CCSc2c(F)cccc21 +C=CCn1c(CNC(=O)c2ccc(C)s2)nnc1SC +Cc1ccc2c(c1)N(CC(=O)NCc1ccco1)C(=O)C(C)O2 +N#Cc1ccccc1-c1ccccc1C(=O)Nc1nnc(C2CC2)s1 +O=C(NCCNC(=O)C1Oc2ccccc2O1)c1ccccn1 +COc1ccc(NC(=O)CCc2ccc3c(c2)OCO3)cn1 +Cc1csc(=O)n1CCC(=O)Oc1ccc2c(c1)OCO2 +Cn1nccc1CCNC(=O)C1CCCN1C(=O)C1CCCCC1 +CCCN(Cc1ccc(C#N)cc1)C(=O)c1cnc(C)cn1 +FC(F)(F)c1cnc2c(Br)cccn12 +COc1cccc2c1CCC2NC(=O)NCCc1nc(C)c(C)s1 +CC(C)c1nnc(NC(=O)c2cc3ccccc3o2)s1 +CC(C)n1[nH]c(=O)c2c1N=C(O)CC21C(=O)Nc2ccc(Cl)cc21 +Cc1ccc2c(CC(=O)OC(C)c3ccccn3)c[nH]c2c1 +COCc1cc(N2CC3CC(C2)C2CCCC(=O)N2C3)ncn1 +Cn1ncc(Br)c1C(=O)N1CCc2ccccc21 +N#Cc1cc(F)ccc1NC(=O)N(CCO)C1CCc2ccccc21 +O=C(COc1ccc(NC(=O)C2CC2)cc1)NC1CCCCC1 +CC(C)(C)CNC(=O)c1cc2ccccc2c(=O)[nH]1 +COc1ccccc1OC1CN(C(=O)c2ccc(C)n(C)c2=O)C1 +Cc1cc(C(=O)Nc2nc(Cc3ccccc3)cs2)n(C)n1 +N#Cc1cccnc1NCCNC(=O)Nc1nncs1 +O=C(c1ccnc(OC2CCC2)c1)N1CCc2c(Cl)cccc21 +NC(=O)CNC(=O)CCOc1ccccc1Br +CCN1CCN(C(=O)C2CC(=O)N(c3ccc(C)cc3C)C2)CC1 +CC(C)(C)C(O)CCNS(=O)(=O)c1cccc(Cl)c1 +Cc1ccc(C(=O)N(C2CCCC2)C2CCCC2)c(=O)[nH]1 +CCc1onc(C)c1NC(=O)C1OCCc2ccccc21 +Cc1cc(CN(C)Cc2nc3ccccc3n2C)ccc1-n1cncn1 +Cn1c(CNC(=O)Cc2cccc(F)c2)nnc1C1CCC1 +Cc1cc(C)n(CC(=O)NCc2ccc(OC(F)(F)F)cc2)n1 +O=S(=O)(Cc1cccc(Cl)c1)NCC(O)c1ccsc1 +OCC1CCCN1c1ncc(C(F)(F)F)cc1Cl +COCc1oc(-c2ccc(OC)cc2)cc1CC#N +CC(C)(C)OC(=O)N1CCC(N2CCc3ccccc32)CC1 +Cc1cc(C)cc(OCCN(C)C(=O)CNC(=O)c2cccs2)c1 +COCCN(C(C)=O)c1nc(CN2CCN(C(C)=O)CC2)cs1 +COC(=O)NCC(=O)Nc1ccc2c(c1)OC(F)(F)O2 +Cc1cc2ncc(C(=O)NCC(=O)NCc3ccco3)c(C)n2n1 +Cc1nc(COC2COC3(CCN(S(C)(=O)=O)CC3)C2)cs1 +COc1cccc(OCC(=O)NCC2(O)CCc3ccccc3C2)c1 +O=C(Nc1cccc(Cl)c1F)c1ccc(-n2cccn2)cc1 +CC(=O)Oc1ccccc1-c1cc2c(C)nc3ccccc3n2n1 +COC(=O)CNC(=O)C1CCN(c2nc3ccccc3n2C)CC1 +CN(C1CCCCC1)S(=O)(=O)N1CCc2cc(F)ccc2C1 +COc1ccc(NC(=O)N=c2[nH]nc3cccc(OC)n23)c(OC)c1 +CCc1cc(C(=O)N(CC(N)=O)C(C)C)sc1C +CN(CC1CCCO1)C(=O)Nc1cccc(Cn2cncn2)c1 +CCC(C)NC(=O)NCCNC(=O)c1cccs1 +Cc1nc(CNC(=O)N(C)Cc2cnn(C)c2)cs1 +CC1Oc2c(cccc2C(=O)Nc2cccn(C)c2=O)NC1=O +Cc1ccccc1CC1(CO)CCCN(c2ncnc3[nH]cnc23)C1 +CCn1nc(CO)c2c1CCN(c1nccc(C3CCCC3)n1)C2 +CC(C)Cc1ccc(S(=O)(=O)N2CCC(=O)CC2)cc1 +CC(C)n1c(C(=O)NCC(=O)N(C)C)cc2sccc21 +Cc1noc(C)c1CCCNC(=O)NC1CCCCC1C +COc1ccccc1CNC(=O)c1nc2ccc(Cl)cn2c1C +CN(C)c1ccccc1C#CCNC(=O)Cc1noc2ccccc12 +CCOCCNC(=O)c1ccc(S(=O)(=O)CC)cc1 +CCCC(=O)N1CCCC1C(=O)N(C)Cc1cnn(C)c1 +O=C(NCCCO)c1nc(-c2cccs2)n(-c2ccccc2)n1 +Cc1ccc(C)c(C(=O)CN(C)Cc2ccsc2)c1 +CC(=O)N1CCOC2CN(S(=O)(=O)c3cccs3)CCC2C1 +O=C(NCC#Cc1ccccc1)NCc1ccccc1 +O=c1oc2ccccc2n1CCSc1ccccn1 +O=C(CC1Cn2ncnc2N=C1O)Nc1ccc(F)c(F)c1 +CCOc1ccc(-n2nc3cc(N)c(Br)cc3n2)cc1 +CCCCCn1c(=O)[nH]c(=O)c2c3c(cnc21)C(=O)CCC3 +Cc1nnc(SC(C(=O)NC2CC2)c2ccc(F)cc2)n(N)c1=O +Cc1ccc(OCC#CCNC(=O)Cc2ccc(Cl)cc2)cn1 +CCN(CC)c1ncnc2c1cnn2-c1ccc(F)cc1 +Cn1ncc2c(Sc3nnc(-c4cccs4)o3)ncnc21 +c1coc(-c2cc(CSc3nc(C4CC4)n[nH]3)no2)c1 +Cc1ccc(Nc2nc(N)nc(N)c2N)cc1Cl +CN(Cc1cc(-c2ccccc2)no1)C(=O)CCCn1cccn1 +CN(CCN(C)C(=O)C1CCC1)C(=O)C1CCC1 +N#Cc1c(F)cccc1NC(=O)c1cc2ccccc2o1 +CC(=O)Nc1ccc(C)n(CC(=O)NCc2ccccc2C)c1=O +CSc1nnc(SC2CCCCC2=O)s1 +CC(Cc1ccc(O)cc1)NC(=O)N(C)CC(=O)NC(C)(C)C +CCc1cc(Br)c2c(c1)NC(=O)CC(C)O2 +Nc1cn(-c2ccccc2)nc1-c1cc2ccccc2o1 +CCN(Cc1ccc(C(=O)N(C)C)cc1)C(=O)c1ccc(Cl)cc1 +COc1cc(NC(=O)C2CCCC2)c(C(=O)N(C)C)cc1OC +CC(OC(=O)c1cnn(C)c1-c1ccccc1)c1nccs1 +COc1ccc(C2CC(O)=Nc3c2ncn3-c2cccnc2)cc1 +O=C1CC(c2nc(C3CC3)no2)CN1c1cccc(Cl)c1 +CCOC(=O)CNC(=O)c1ccc(SC)cc1OC +CCOC(=O)C(C)N1CCC2(CCC1=O)NC(=O)c1ccccc1O2 +Cc1nonc1NC(=O)c1c(-c2c(F)cccc2Cl)noc1C +CC1COCCN1C(=O)c1ccccc1C(F)(F)F +COc1cc(C(=O)N=c2sccn2C)ccc1OC(C)C +N#Cc1cccc(NC(=O)CSc2ncnc3ccccc23)c1 +Cc1noc(C)c1C(=O)Nc1ccc(N(C)C)nc1 +O=S(=O)(CCOC1CCCCCC1)c1nnc(NC2CC2)s1 +N#CCCN(C(=O)c1ccc(Cl)cc1)C1CCCCC1 +CCOc1cc(NCc2ccc(OC)cc2)ncn1 +NC(=O)c1cnn(-c2ccc3ccccc3n2)c1N +CCOC(=O)CCC(C)NC(=O)c1cnn(C)c1 +CCOc1ccc(-c2nc3n(c2CO)CCS3)cc1OCC +CCOCC1CCCN(C(=O)c2ccc(C(=O)N(C)C)cc2)C1 +CCC1C(=O)NCCN1C(=O)Cc1cccc(OCC#N)c1 +COC(=O)CCC(=O)NCC(C)(C)c1ccc2c(c1)OCCO2 +OC(Cn1c(C(F)F)nc2ccccc21)c1ccccc1 +COc1cccc(C2CC2C(=O)N=c2[nH]nc3cc(C)ccn23)c1 +O=C(Oc1ccccc1)c1occc1CS(=O)(=O)c1ccccc1 +COC(=O)c1c(C)nn(-c2nc3ccccc3[nH]2)c1C +Cc1sc(NC(=O)C2CC2)c(C(=O)OC(C)C#N)c1C +Cc1nn(-c2ccc(F)cc2)c(C)c1CC(=O)N(C)C1(C#N)CCC1 +c1ccc2c(c1)ccn2CCCn1cc(-c2ncc[nH]2)nn1 +FC(F)(F)c1ccccc1Cn1cnc2cccnc21 +Cc1ccc2c(CNC(=O)c3cccc(F)c3)cc(=O)oc2c1 +COC(=O)c1ccc(C(=O)Nc2cc(-c3cccs3)n[nH]2)cc1 +COCCCNC(=O)c1oc2ccc(Cl)cc2c1C +CC(C)(C)OC(=O)N1CCCC(CS(=O)c2nccs2)C1 +CCCNc1ncc(-c2nc3cc(-n4cnnn4)ccc3[nH]2)cn1 +CN(CC(=O)NC(C)(C)C)C(=O)CNc1ccc(Cl)c(F)c1 +COc1ccc(C(=O)Nc2cccc(C(=O)N3CCCCC3)c2)cc1 +O=C(OCc1cccnc1)C1CCN(C(=O)C2CC2)CC1 +COc1ccc2[nH]c(=O)c(CNc3ccc(C)c(F)c3)cc2c1 +CSc1nc(C(C)C)nc(C)c1C(=O)NC1CCc2ccccc21 +CCOCc1ccc(CNC(=O)C2CC=CC2)cc1 +COc1cccc(C(=O)Nc2cccc(-c3nnco3)c2)c1OC +C=CCNS(=O)(=O)c1ccc(Cl)cc1Cl +CC(NC(=O)C1CN(Cc2ccccc2)CCO1)C1CCCO1 +COc1ccc(NC(C)=O)cc1NCc1ccccc1F +O=C(CCC(=O)c1ccc(F)cc1F)Nc1cccc2cn[nH]c12 +Cc1n[nH]c(C)c1NC(=O)Cc1ccc(OCC(C)C)cc1 +CC(=O)c1cc(C)ccc1OCC(=O)NC1CCCC1 +O=C(Cn1cnc2c([nH]c3ccc(F)cc32)c1=O)NC1CCCCC1 +O=C(NCc1ccc(CO)c(F)c1)C1CCCN(c2ncccn2)C1 +COc1ccccc1NC(=O)c1cc2ccoc2cn1 +CN(C)S(=O)(=O)CCCOC(=O)c1n[nH]c(=O)c2ccccc12 +COc1ccc(OC)c(NC(=O)c2c(C)nc3ccccn23)c1 +CC1CCN(C(=O)NCc2cc(F)ccc2F)CC1 +COc1cccc(C(=O)N2CCN(CC3CCCO3)CC2)c1 +C=CCn1c(SCc2nc3ccccc3[nH]2)nnc1-c1ccccn1 +c1ccc2[nH]c(C3CCCN3c3ccc4nccnc4n3)nc2c1 +Cc1ccc(CNc2cc(C(=O)N3CCCCC3)nc(C)n2)cc1 +CNC(=O)C1CCCN1C(=O)c1cc2ccccc2[nH]1 +O=C(c1cc(=O)c2ccccc2o1)N1CCCCCC1 +CCOC(=O)c1c[nH]c2ccc3ccccc3c2c1=O +Cc1cc(C)n(CCCn2ccnc2-c2[nH]cnc2C)n1 +O=C1CCCCC1Sc1n[nH]c(=O)n1CC1CCCO1 +CCCOc1ccc(C(=O)Nc2cc(C)ns2)cc1OCC +Cc1cccc(C)c1NC(=O)CCNC(=O)c1ccoc1 +N#Cc1ccnc(N2CCN(CC(O)COCc3ccco3)CC2)c1 +OC1C2CCCC1CN(c1ccc(Br)cn1)C2 +COc1ccccc1C1NCCc2ccc3[nH]ccc3c21 +COC(=O)c1nc(Cc2ccccc2)[nH]c(=O)c1O +COCCN1CCC2(CCC1=O)CN(c1nccs1)CCN2C +O=C1CC(NC(=O)Cc2ccc(Cl)cc2)CN1 +CCCCCOc1ccc(C(=O)Nc2cc[nH]n2)cc1 +CC(CO)NS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 +CC12CCC(C)(C(NC(=O)C34CCC(C)(C(=O)O3)C4(C)C)C1)C2(C)C +COCCN(CC(=O)N(C)C)C(=O)c1n[nH]c2ccccc12 +Cn1cnnc1CNC(=O)NC(c1ccccc1)C1CCCC1 +Cc1c(N)cccc1C(=O)Nc1ccccc1N1CCOCC1 +Nc1onc(C2CC2)c1-c1cccc(Br)c1 +CCOc1c(Cl)cnn(-c2ccccc2)c1=O +COc1ccc(CCc2nnc(N3CCCC3)o2)cc1N +COC(=O)CNC(=O)c1ccc(-c2cccc(Cl)c2C)o1 +Cc1c(C(=O)OCCNc2cccnn2)oc2ccc(Cl)cc12 +O=C(Nc1cccc(F)c1)c1ccc2ncsc2c1 +COCc1c(C(=O)NC(C#N)c2ccccc2F)oc2ccccc12 +Cc1ccc(CNC(=O)c2cnc3scc(C)n3c2=O)o1 +Cc1cc(F)ccc1CCNC(=O)C(C)OCC(F)(F)F +COc1c(C(=O)NCC(C)Oc2ccc(Cl)cc2)c(C)nn1C +O=C(Nc1ccccc1-n1cncn1)c1ccn(-c2cccc(F)c2)n1 +CC(NC(=O)c1csnn1)c1cccc(Cl)c1 +Nc1ncccc1C(=O)Nc1ccc(OC(F)(F)F)cc1 +CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccsc2)CC1 +Cc1noc(C2COCCN2c2ncc(Br)cn2)n1 +Oc1ccc(CCNCc2ccccc2Cl)cc1 +CN(C)c1c(Cl)cccc1NC(=O)c1cccnc1 +Cc1csc(CNC(=O)C2CCCCN2C(=O)OC(C)(C)C)n1 +O=C(CCc1ncc(-c2ccccc2)o1)N1CCN(CCO)CC1 +Cc1nn(C)cc1CN(CCc1cccc(F)c1)C1CC1 +Nc1occ(C(F)(F)F)c1C(=O)c1ccccn1 +COc1ccc(C#CCNC(=O)NCCc2ccccc2)cc1 +O=C(Cc1ccccc1)Nn1c(-c2ccc(F)cc2)csc1=O +Cc1cc(NC(C)c2ccccc2Br)n2ncnc2n1 +CC(=O)Nc1ccc(C)c(NC(=O)c2ccc(-n3ccnn3)cc2)c1 +c1nc(NCc2ccoc2)c2c3c(sc2n1)CCCC3 +CC(C)N(CCCO)c1ccc(N)c(C(N)=O)c1 +CCSc1nc(C)cc(C(=O)N2CCc3ccccc3C2)n1 +Cc1oc(-c2ccco2)nc1CC(=O)N(CCC#N)c1ccccc1 +COc1ccccc1NC(=O)c1csc(Nc2cccnc2)n1 +Nc1cccc(OCc2cc(Cl)c3c(c2)OCO3)c1 +CC(NC(=O)OC(C)(C)C)C(=O)N(C)Cc1ccoc1 +Cc1ccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)cc1 +COC(=O)N1CCC(NC(=O)N(C)Cc2ccc(C)s2)CC1 +CC(NC(=O)c1cccc(C(F)(F)F)c1)C1CCCO1 +Nc1nc2nc3c(c(-c4ccc(Cl)cc4)c2c(=O)[nH]1)C(=O)CCC3 +COc1ccc(OC)c(C(C)NC(=O)c2ccc(C)s2)c1 +O=C(Cn1nc2ccccn2c1=O)OC1CCCCC1 +COc1ccc(-c2c(CO)nnn2-c2cccc(OC)c2)cc1 +CC(C)CNC(=O)CCNC(=O)c1ccc(Cl)cc1 +COC(=O)CSc1nc2ccccc2c(=O)n1-c1cccnc1 +CCN(CCC#N)C(=O)CNc1cccc(Cl)c1-n1cccn1 +O=C(Nc1nncs1)C1CCCN(c2nc3ccccc3s2)C1 +CCCOc1ccccc1NC(=O)C(C)NC(C)=O +Fc1cc2c(cc1C(F)(F)F)CCNC2c1cnccn1 +CCOc1cc(S(=O)(=O)N2CCOCC2)ccc1Cl +COCc1ccccc1C(=O)NCC1(C(N)=O)CCOCC1 +Cc1cccc(OCC(=O)Nc2ccccc2N2CCCC2=O)c1 +Cc1ncsc1CCOC(=O)C1CCN(C(=O)C(C)C)CC1 +O=C(NCc1cccnc1-n1cncn1)c1ccsc1 +Cc1cccc(NC(NC(=O)c2ccco2)C(=O)c2ccccc2)c1 +CC(O)CN(C(=O)Cc1ccc(F)c(F)c1)C(C)C +O=c1ccc(S(=O)(=O)NC2(CO)CCCCC2)c[nH]1 +Cc1ccc(OCCNC(=O)Cc2cccs2)cc1 +Cc1nnc(SCC(=O)Nc2ccnn2C(C)C)n1N +CCC(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccco2)cc1 +COc1ccc(C2CCCN2C(=O)c2ccc3c(c2)OCO3)cc1 +Cc1c(CNC(=O)c2c(O)cc(F)cc2F)cnn1C +c1ccc2c(c1)NCC2Cc1ccc2c(c1)OCCO2 +CCC(C(=O)OCC(C)C)N1C(=O)COc2cccc(N)c21 +O=C(NCc1ccco1)Nc1cc(F)ccc1Cl +CN1CCN(C(=O)CN2C(=O)c3ccccc3S2(=O)=O)CC1 +Cc1nc(-c2ccccc2)ccc1C(=O)N1CCCC(n2cccn2)C1 +CC(C)(C)c1noc(OCc2nnc(C3CC3)o2)n1 +CS(=O)(=O)c1ccc(F)c(Br)c1 +CNS(=O)(=O)c1cccc(NC(=O)c2cc[nH]n2)c1 +CC(C)NC(=O)c1cccc2c1C(=O)N(C1CCCCC1)C2 +CC(C)c1noc(CCNC(=O)Cc2cccc3ccccc23)n1 +C#Cc1cccc(N(CC(=O)Nc2c(C)nn(C)c2C)C(C)C)c1 +COCc1c(C(=O)N2CCC(OCc3cccnc3)CC2)noc1C +COc1ccc(OC)c2c1CCNC2C1CCOCC1 +CCNS(=O)(=O)c1ccc(CNc2ncnc(CC)c2F)cc1 +CC(=O)C(C)n1cnc2scc(-c3ccc(Cl)cc3)c2c1=O +O=C(CCc1nc2ccccc2[nH]1)N1CCN(c2ccccc2)CC1 +CCN1CCN(C(=O)NCc2cccc(OC)c2)c2cccnc21 +C#CCCOC(=O)c1ccc(OC)c(OC)c1OC +Nc1ccc2c(c1)N(CC(=O)N1CCOCC1)CCO2 +C#CCN1C(=O)COc2ccc(Br)cc21 +Cc1cccc(-c2nnc(COC(=O)Cc3c(C)noc3C)o2)c1 +Cc1cc(C)c(CNC(=O)NCC(C)(C)c2ccc(F)cc2)c(=O)[nH]1 +COc1cc(C)c(COC(=O)CN)cc1C(C)(C)C +O=C(c1cccs1)N1CCC(Cn2cccn2)CC1 +COC(=O)c1cc(-c2ccc(OCC(C)C)c3ncccc23)n[nH]1 +COc1ncccc1CNC(=O)CC(NC(C)=O)c1cccs1 +CCOc1ccc(-n2nnc(-c3ccco3)c2N)cc1 +O=C(Nc1cccc(Cl)c1F)c1cccc(N2CCCC2=O)c1 +CC(=O)c1ccc(S(=O)(=O)NCc2ccoc2)cc1 +CC1CN(C(=O)c2cnn(-c3ccccc3)c2)c2ccccc2S1 +Cc1ccc(C=CCC(=O)N(C)c2ccc(S(C)(=O)=O)cc2)cc1 +CCOC(=O)CN(C(=O)c1ccc(C)cc1C)C(C)C +CC(C)N(C)C(=O)NCC(C)(C)c1ccc2c(c1)OCCO2 +CC(C)c1noc(-c2ccccc2C(=O)Nc2ccc(C#N)cc2)n1 +CC(=O)NCC1CCCN(S(=O)(=O)c2ccc(C(C)=O)cc2)C1 +CC(Oc1cccc(N)c1)C(=O)N1CCc2ccccc21 +CN(Cc1ccccc1OC(F)(F)F)C(=O)c1ccc(=O)[nH]c1 +CC1(C(=O)Nc2ccn(-c3ncccc3Cl)n2)CC1(Cl)Cl +CC(=O)c1ccc(C)cc1OC(=O)c1cnns1 +COC(C)(C)c1noc(-c2ccc(CNC(=O)C(C)(C)C)cc2)n1 +Cc1cc(C(O)c2cccs2)c2c(c1)C(C)(C)C(=O)N2 +c1ccc(NC2CCN(c3ncnc4[nH]cnc34)C2)cc1 +COc1cccc(C(=O)NCc2ccnc(-n3cccn3)c2)c1O +COc1ccc(C(=O)N(C)Cc2ccc(C)cc2C)cc1OC +O=C(Nc1ccnc2ccnn12)C1(c2cccc(Cl)c2)CC1 +Cc1cc(CN(CC(C)C)c2c(N)n(CC(C)C)c(=O)[nH]c2=O)no1 +O=C(NC1CCc2c(Cl)cccc21)c1scnc1C1CC1 +Cc1cc(OC(C)C)ccc1NS(=O)(=O)c1cn[nH]c1 +CCNC(=O)N1CCN(Cc2nc3ccc(Cl)cc3c(=O)[nH]2)CC1 +CCNC(=O)CNc1ccc(C(=O)N(CC)CC)cc1 +Cc1ccc(C(=O)N2CCN(Cc3nc(C)no3)CC2)cc1 +CC(CO)CNC(=O)NC(C)c1ccc2ccccc2c1 +COC(=O)c1ccc2c(c1)C(CC1=CCCCC1)NCC2 +CC(C)Oc1ccc(NC(=O)CCNC(=O)C2CC2C)cc1Cl +Cc1cc(C)n(C2CN(Cc3nnnn3C3CC3)C2)n1 +Cc1ccc(-c2nc(CCNC(=O)c3cnn(C)c3C)cs2)cc1 +CCCS(=O)(=O)NCC(O)c1cn(C)c2ccccc12 +CCCCCNC(=O)c1n[nH]c2c1CN(C(=O)COC)CC2 +CN(Cc1cnn(Cc2ccccc2)c1)C(=O)c1cc(C2CC2)on1 +COc1ccccc1C(=O)c1ccc(N2CCCC2)o1 +CCOc1ccc(C#N)cc1NC(=O)c1ccco1 +O=C(NCCc1csc(-c2ccccc2)n1)Nc1nccs1 +Cc1cc(C(=O)N2CCC(CNC(=O)C(C)C)CC2)no1 +COc1cc(C)c(C)cc1C(=O)COc1ccccc1N +O=C(Nc1ccc(C(=O)N2CCCC2)cc1)NC1CCCCC1O +CC(c1ccc(Cl)cc1)N(C)C(=O)c1cc(F)cc2[nH]cnc12 +CCOCc1ccc(CNC(=O)c2ccsc2)cc1 +Cc1cccc(C)c1NC(=O)c1cccc(N(C)S(C)(=O)=O)c1C +O=C(NC1CCCN(Cc2ccccc2)C1=O)c1cnccn1 +COCc1cc(-c2cn(CC(O)CO)nn2)ccc1OC +Nc1nc(CSc2ccccn2)nc(Nc2ccccc2)n1 +Cc1nc(CSc2nc(N)cc(N)n2)oc1C +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)COC +CCN1CCN(C(=O)c2cnc(C3CC3)nc2N)CC1 +Cc1oc(C)c(C(=O)Nc2ccc3c(c2)CCC(=O)N3)c1C +CSc1ccc(C(O)CNC(=O)NCc2ccccc2)cc1 +O=C1CN(C(=O)CS(=O)(=O)c2ccc(Cl)cc2)CCN1 +CNC(=O)c1cc(NC2CCOCC2)ccc1Cl +COc1ccc(C(O)C(=O)Nc2cccc(C)c2C)cc1 +C#CCNC(=O)CSc1ccc(F)c(Cl)c1 +O=C(Cc1ccc[nH]1)N(Cc1ccccc1)CC1CCCO1 +COc1cc(C)ccc1C(=O)Cn1cc(Cl)cn1 +CCCCCNC(=O)c1cc(OC)c(S(N)(=O)=O)s1 +CCOc1ccccc1C(=O)Nc1ccc(NS(C)(=O)=O)cc1 +CC(Sc1nnc(C2CC2)n1C)C(=O)N1CCCc2ccccc21 +Cc1cc(C)n2ncc(C(=O)N(C)C3CCCc4ccccc43)c2n1 +O=c1c2c([nH]c3c(-c4ccccc4)cnn13)CCCC2 +COc1ncccc1C1NCCc2c1ccc(C)c2Cl +CCOC(=O)N1CCC(NC(=O)c2cc(C)n(C(C)C)c2C)CC1 +C=CCNC(=O)Cc1nc(CNc2ccc(C)cc2)n[nH]1 +COc1cc(C)c(S(=O)(=O)NC(C)c2ccc(C)cc2)cc1OC +CNC(=O)C1CCCCC1NC(=O)CCCc1cc(F)ccc1F +CNC(=O)c1ccccc1NC(=O)C(c1ccccc1)c1ccccc1 +Cc1nc(-c2ccc3c(c2)NCC(C)O3)c(C)s1 +CCCn1cc(N)cc1C(=O)NCC1CCCCC1 +CCOc1ccc(C(F)(F)F)cc1NCc1nc(C)c(C)o1 +Cc1cc(C)n(CC(C)CNC(=O)c2ccsc2)n1 +Cc1ccc(CNC(=O)NCCCN2CCOCC2)cc1 +CCCNC(=O)CNS(=O)(=O)c1ccc(O)c(N)c1 +Cc1nc(C)c(C(=O)C(C#N)c2nc3cc(Cl)ccc3s2)s1 +CNC(=O)CN1CCc2nc(NC(=O)NC3CCCC3)sc2C1 +CC1CCCC(NC(=O)C(C)N2CCN(S(N)(=O)=O)CC2)C1C +Cc1cc2oc3c(c(=O)c2cc1C)C(c1ccccn1)N(C)C3=O +COc1cc(C(=O)NC2CCCCC2)cc(OC)c1OC +CC(=O)c1nnn(CC(=O)Nc2cc(C)cc(C)c2)c1C +CC(=O)Nc1ccc(C2NCCc3c(O)ccc(C)c32)cc1 +C#CC(C)OC(=O)c1cc(N2CCCC2=O)ccc1Cl +CN(CC(=O)N1CCOCC1)C(=O)c1ccc(Cl)cc1 +CC(C)c1cccc(NC(=O)NCCC(=O)N2CCCC2)c1 +CCC1CN(C)c2ccccc2CN1C(=O)c1cc(C)no1 +CCN(C(=O)c1ccc(C)c(NS(C)(=O)=O)c1)c1ccccc1 +O=C(Nc1ccc2c(c1)CNCC2)c1ccccc1Br +CNC(=O)COc1cccc(NC(=O)NCc2cccc(O)c2)c1 +O=C(CCn1cnc2sccc2c1=O)Nc1ccccc1O +O=C(Cc1ccccc1F)Nc1ccccc1N1CCCC1=O +O=C(NCCNS(=O)(=O)c1ccccc1)c1cnccn1 +CCCNC(=O)C1CCCN(C(=O)c2ccc(C)cc2O)C1 +CCC(C)NC(=O)Cn1c(-c2ccccc2)cc(C(C)=O)c1C +CCCCS(=O)(=O)NC(CC)c1cccs1 +CC(=O)Nc1cc(NC(=O)c2ccco2)ccc1F +CCCc1cc(NCCNc2cccnc2)n2nccc2n1 +CC(=O)Nc1ccc(F)c(C(=O)NCc2cccc(Cl)c2)c1 +CC(C)N(Cc1ccccc1)C(=O)c1scnc1C1CC1 +CCOCC(=O)Nc1cccc(C(=O)N2CCCCC2C(=O)OC)c1 +CCn1nc(C(=O)Nc2cccc(F)c2)c(=O)c2cc(Cl)ccc21 +CS(=O)(=O)NCCc1nccn1Cc1ccccc1 +O=C(NCC(O)c1ccccc1)C1Cc2ccccc2CN1 +CCc1nc(NCc2cnn(-c3ccccc3C)c2)c2cnn(C)c2n1 +CC(Nc1nc2cc(Br)ccc2s1)c1nncn1C +O=C(OC1CCOC1)c1cnc(C2CCCO2)s1 +CC1CC1CNC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +Nc1cc(Cl)ccc1C(=O)NCc1ccccc1F +COc1ccc(C(=O)Cc2nc3ccccc3[nH]2)cc1OC +CCC(=O)Oc1cc(C)c(CN2CCOCC2)cc1C +Cc1nn(C(F)F)c(C)c1CC(=O)OCC1CC(=O)N(C2CC2)C1 +CC(C)CC1COCCN1Cc1nnc(-c2ccc(Cl)cc2)o1 +Cn1ncc2c(SCc3ccccc3Oc3cccnc3)ncnc21 +Cc1occc1CN(C)C(=O)C1(c2cccc(F)c2)CCOCC1 +CCCC(=O)N(CCc1cccs1)Cc1ccoc1 +CCOc1ccccc1CNC(=O)c1ccnc(-c2cccs2)c1 +Cc1cnc2[nH]c(C(F)(F)F)c(CN3CCOCC3)c2c1 +CCOc1ccc(CC2COc3ccccc3C2)nn1 +COc1ccc(S(=O)(=O)NC2CC2)cc1NCc1cccc(C)c1 +Cc1cc(=O)oc2c3c(ccc12)OCN(CCCc1ccco1)C3 +CCCC1CCC(NC(=O)NC(C)C(=O)N2CCCCC2)CC1 +CC(NC(=O)c1n[nH]c(=O)c2ccccc12)c1ccc(F)cc1F +Nc1cc(Cl)ccc1S(=O)(=O)NCC1CCC1 +COC(=O)Cn1c(CCNC(=O)C2CC2)nc2ccccc21 +CCN1CCN(C(=O)C(C)Sc2nc(C(C)C)n[nH]2)CC1 +CN(C1CCC(C)(C)CC1)S(=O)(=O)c1cn(C)c(=O)n(C)c1=O +COc1ccc(N)cc1-c1n[nH]c(-c2cccc(C)c2)n1 +COCC(=O)NCC#CCOc1ccccc1OC +N#CCCN(Cc1ccccn1)Cc1cccc2c1OCO2 +CCCOc1cc(C)ccc1NCc1ccccn1 +Cc1ccc(F)cc1C(=O)Nc1ccc(-n2ccnc2C)nc1 +CC1COc2c(Cl)ccc(Cl)c2N(C)C1=O +COCC1c2nnn(CC3CC3)c2CCN1Cc1cccc(OC)c1 +CN(C)c1ccc(NC(=O)c2cnccn2)c(C(F)(F)F)c1 +CCOC(=O)c1sc(NC(=O)OC)c(C(=O)OC)c1C +CC(=O)Nc1ccc(C(=O)N2CCC(Oc3cnccn3)CC2)cc1 +CN1CCN(C(=O)CS(=O)c2ccncc2N)CC1 +COc1ccccc1-c1nnc(-c2ccc(N)cc2)o1 +CC1(C)CCCN1C(=O)c1sccc1Br +CCOC(=O)NC(C(=O)NC1c2ccccc2CC1O)C(C)C +CC(CO)(CO)NC(=O)Nc1cc(Br)ccc1F +COc1ccc(OCC(=O)NCC(C)(O)c2ccsc2)cc1 +CC(=O)N1CCN(CCNC(=O)NC2CCOc3ccccc32)CC1 +CSc1cccc(NC(=O)c2cn(C)nc2C)c1 +CC1C(=O)N(c2ccc(Br)cc2)CCN1C(=O)C1CC1 +COc1ccc(OC)c(NC(=O)N(C2CC2)C(C)C2CC2)c1 +Cc1csc(CCNc2ncnc3cc(F)ccc23)n1 +O=C(Cc1csc(-c2cccc(F)c2)n1)OCCN1CCCC1=O +CCc1cc(-c2ccccc2CO)nc(N2CCOCC2)n1 +C#CCNC(c1c(C)nn(-c2ccccc2)c1C)C(F)(F)F +Cc1cc(NC(=O)CNc2cc(NC(=O)C3CC3)ccc2C)on1 +CCOc1ccnc(N2CCN(Cc3ccc4c(c3)OCO4)CC2)n1 +COC(=O)Cc1csc(NC(=O)c2cc(Cl)c[nH]2)n1 +Cc1nn(C)c(C)c1CC(=O)N1CCCc2cccc(OC(F)F)c21 +C=CCn1c(C)cc(C(=O)CN2CCC(C(=O)NC)CC2)c1C +CC(=O)Nc1cccc(CNC(=O)Nc2ccc3nc(C)oc3c2)c1 +CC1(C(=O)N(Cc2ccco2)c2ccccn2)CC1(Cl)Cl +CCc1nnc(NC(=O)Cc2noc3ccc(C)cc23)s1 +Cc1cccc(C(=O)N2CCC(c3ccnn3CCO)CC2)c1Cl +CC1CCc2sc(C(=O)N3CCC(CO)CC3)cc2C1 +O=C1COc2cc(NC(=O)c3cn(Cc4ccccc4)nn3)ccc2N1 +CC(C)n1nc(Cn2cccc2)c2c1CN(C(=O)c1ccc[nH]1)C2 +CCc1ccccc1NC(=O)Cn1c(=O)c(C)nc2ccccc21 +NS(=O)(=O)c1ccc(NC(=O)c2ccc3nccnc3c2)cc1 +CC1CCN(S(=O)(=O)NCC(C)N2CCOCC2)CC1 +CC(C)c1csc(NC(=O)CC2OC(=O)c3ccccc32)n1 +CS(=O)(=O)c1cc(Nc2ccccc2)ccc1O +COc1cc(C)c(C)cc1SCC(=O)N1CCNCC1 +NC(=O)c1ccc(Cl)c(NC(=O)CCc2ccc(F)cc2)c1 +Cc1c(C(=O)NCCC(=O)N2CCCCCC2)[nH]c2c1C(=O)CCC2 +CN(C)C(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +COCc1cc(N2CCCC(c3ccccc3)CC2)n2ncnc2n1 +CN(C)S(=O)(=O)N1CCc2[nH]nc(Nc3ccccc3)c2C1 +CCC(O)CN1CCN(C(=O)c2cc(C)nc3ccc(C)cc23)CC1 +Cc1ccc(-c2ncc(CN3CCOC(C(N)=O)C3)s2)cc1 +COc1ccc(Cl)cc1C(=O)N1CCN(c2ccccc2O)CC1 +Cc1ccc(NCc2cccc(C(N)=O)c2)cc1C +CC(CNC(=O)Cc1noc2ccccc12)c1cccs1 +Cc1ccc(C)c(CNc2ccc(C(N)=O)cc2)c1 +O=C(NCCN1CCOCC1)C1CCCN1C(=O)c1ccco1 +CCn1nc(C(=O)NC)c2c1CCC(NCc1cccc(C)c1)C2 +CCCNC(=O)c1ccc(-n2nncc2-c2ccc(F)cc2)cc1 +Cc1ccc(CNC(=O)c2csc(Nc3cccc(C)n3)n2)cc1 +N#Cc1ccc(Cn2sc3ccccc3c2=O)cc1 +Cc1ccc(N2CCC(NC(=O)OC(C)(C)C)C2)nn1 +Cn1c2c(c3c(Br)cccc31)COCC2 +O=C(Nc1ccccc1-n1cnnn1)c1cn(Cc2ccccc2)nn1 +O=C(Cc1cc2ccccc2[nH]c1=O)OCCOc1ccccc1 +CCc1[nH]c(C(=O)Nc2cc(F)ccc2C)c(C)c1C(=O)OC +N#Cc1ncn(CC(=O)N2CCCC2c2ccc3c(c2)OCCO3)n1 +Cn1cccc1Cc1nnc(SCC(=O)NC2CCCCC2)n1C +CCCN(C)C(=O)NCCc1ccc2c(c1)OCCO2 +O=C(Nc1ccc(N2CCCCC2)cn1)c1ccc[nH]c1=O +Cc1occc1C(=O)N1CCC2(CCCN(CC3CCC3)C2=O)C1 +Nc1ccn(CC(=O)NCCn2ccc(C3CC3)n2)n1 +COc1cn(-c2ccccc2)nc1C(=O)Nc1ccccc1 +NC(=O)C1CCCN(C(=O)CC(c2ccccc2)c2ccccc2)C1 +CCCCNC(=O)Oc1ccc2c(c1)c(C(=O)OC)c(C)n2C +Cc1nc(-c2ccccc2F)sc1C(=O)N(C)C +Cc1ccc(S(=O)(=O)N2CCNCC2)c(Br)c1 +COC(=O)C1CC(NC(=O)c2cc(Cl)cc(OC)c2)CN1C +O=C(C1CCCN(C(=O)C2CC2c2ccco2)C1)N1CCCCC1 +NC(=O)c1ccc(NC(=O)Cn2nc3c(cc2=O)CCCCC3)cc1 +CC1CCc2sc(C(=O)OCCNC(=O)c3ccncc3)cc2C1 +CCCN(Cc1ccsc1)C(=O)C1CCCC1 +CC(C)Oc1ccc(NS(=O)(=O)c2cccc(O)c2)cc1 +O=C1NCCN1Cc1cccc(OC(F)(F)F)c1 +Cc1nn2cc(CCCOC(=O)Cc3cccnc3)cnc2c1C +Cc1csc(COc2cccc(Oc3ncccn3)c2)n1 +CS(=O)(=O)NC1=NCN(CCN2CCOCC2)CN1 +O=C1CCC(n2nnc3ccccc32)N1Cc1ccccc1 +CN(c1ccc(Cl)cn1)S(=O)(=O)c1ccccc1 +CC(C)C(=O)NCCNS(=O)(=O)c1ccc(C#N)cc1 +Cc1oc(-c2ccco2)nc1CC(=O)N1CCCC(n2cccn2)C1 +CCN(C(=O)CS(=O)(=O)c1cc(C(C)(C)C)ccc1C)C1CC1 +CCn1cc(C#N)c(=O)n(Cc2sc(C)nc2C)c1=O +CCC(C)NC(=O)CSc1nnnn1-c1ccc(O)cc1 +CCCC(=O)Nc1nnc(C2CC(=O)N(c3cccc(C)c3)C2)s1 +CC(C)CCNC(=O)Cn1nnc2ccccc2c1=O +Cc1ccccc1-n1ccnc1SCC(=O)Nc1cc[nH]n1 +Cn1cnnc1SCC(=O)NCc1nnc2ccccn12 +COc1cccc(CN(C)S(=O)(=O)c2ccc(F)cc2F)c1 +CS(=O)(=O)c1ccc(Cl)c(NC(=O)C2(c3ccccc3)CC2)c1 +CC(=O)c1c[nH]c(C(=O)NCCc2ccccc2C)c1 +CCCCNC(=O)C(C)Sc1nnc(C)n1-c1ccccc1C +O=C(Nc1nc(-c2ccccn2)cs1)C1CC(=O)N(CC2CC2)C1 +CC(=O)c1ccccc1NC(=O)c1ccc(F)nc1 +Cc1ocnc1CNS(=O)(=O)c1cc(F)ccc1F +CC(C)Oc1cccc(CNC(=O)Nc2ccccc2CC(N)=O)c1 +N#Cc1ccsc1NC(=O)CCCS(=O)(=O)c1ccccc1 +Cc1ccc2c(c1)-c1c(cnn1CC(=O)Nc1cccc(C#N)c1)CO2 +Fc1ccc(NCc2nnc(C3CCC3)o2)c(OCC2CC2)c1 +CCC(C)(C#N)NC(=O)c1nnn(-c2ccc3c(c2)OCCO3)c1C +Cc1csc(C(C)Nc2nccc(C(F)(F)F)n2)n1 +CC(=O)c1ccc(OC(C)C)c(NC(=O)C2CC2)c1 +COc1cccc(OC)c1OCC(=O)N(C)C1CCC(C)CC1 +CCOCCNC(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +Cc1ccc(-n2nnnc2SCCCCCO)cc1 +CCc1ccc(C(=O)Nc2ccc(C(=O)c3nccn3C)cc2)cc1 +Cn1cccc1C(=O)N(CCC#N)CCC(F)(F)F +Cn1cc(CNc2ccc(N3CCOC3=O)cc2)c(-c2ccncc2)n1 +O=C(Nc1nncs1)c1cccc(Oc2ccccc2)c1 +COc1cc(C(=O)Nc2cccc3cn[nH]c23)cc(OC)c1C +CSc1ccc(NC(=O)NC(C)(CO)C2CC2)cc1Cl +N#Cc1ccc(Nc2ccc3c(c2)OCCCO3)cc1 +C=C(C)COc1ccccc1C(=O)N1CCCC1c1c(C)noc1C +Cc1cccc(-c2nc3cc4c(cc3n2CCCO)OCCO4)c1 +COc1ccc(S(N)(=O)=O)cc1C(=O)N(C)Cc1ccccc1C +COc1ccnc(NC(=O)C2CCCN2C(=O)Cc2cccs2)c1 +CCCNC(=O)NCc1ccc(C(=O)N2CC(C)OC(C)C2)cc1 +Cc1cnc(C(=O)Nc2cc(C(F)(F)F)ccc2-n2cccn2)cn1 +O=C(NCCc1ccccn1)c1ccc(Cl)cc1Cl +COC(=O)Nc1ccc(OC(=O)c2cccn2C)cc1 +CSc1ccc(Cl)c(C(=O)Nc2ccc(-n3cncn3)cc2)c1 +O=C(NCCCn1ccc2cccnc21)c1cc2ccccc2oc1=O +O=C(C1CC1)N1CCCC(C2CC(C(F)F)n3ncnc3N2)C1 +CC(C)(C)OC(=O)N1CCC(C(=O)Nc2ccc(F)cc2F)CC1 +C=CCn1c(=O)oc2cc(NC(=O)Nc3ccccc3F)ccc21 +CCc1c(C(=O)N(CCC#N)Cc2cccnc2)[nH]c(C)c1C(C)=O +COc1cccc(C(=O)NC(C)c2ccc(-n3cncn3)cc2)c1F +CC(C)CC(C)OCCC(=O)Nc1nc2c(s1)C(=O)CCC2 +COc1ccc(C(C#N)NCc2ccccn2)cc1 +CC1CCC(NS(=O)(=O)c2ccc3c(c2)oc(=O)n3C)CC1 +COc1ccc(C(=O)NCCc2cn3ccccc3n2)c(OC)c1 +Cc1cc(C)c(NC(=O)Cn2ncc(=O)c3ccccc32)c(C)c1 +CCCc1nc2ccc(N)cc2c(=O)n1Cc1ccccc1Cl +COC(=O)C1CC(NC(C)=O)CN1Cc1cc(C)ccc1C +O=c1nc(CN2CCCC2c2ccsc2)[nH]c2ccccc12 +CN(Cc1coc(-c2ccccc2)n1)C(C(N)=O)c1cccc(F)c1 +CCOC(=O)C(O)Cc1nccn1-c1cccc(C#N)c1 +COCCOC(=O)c1[nH]c2c(c1C)C(=O)CC(c1cccs1)C2 +CC(=O)N(C)CC(=O)NC1CCCC1Cc1ccccc1 +O=C(NC(c1ccccc1)c1nnc(N2CCCCC2)o1)C1CCC1 +CCN(CC(=O)NC(C)(C)C)C(=O)Cc1c[nH]c2ccccc12 +C#CC1(O)C(O)C(CO)OC1n1ccc2c(N)ncnc21 +CC(C)CC(NC(=O)NCC(C)N1CCOCC1)c1cccs1 +C=CCN1CCN(S(=O)(=O)CC)Cc2cccnc21 +CCC(C)CN(C)c1ccc(F)cc1CN1CCOC(C#N)C1 +CC(C)Cc1cc(C(=O)N2CCCC(OCc3ccccn3)C2)on1 +CC(=O)N(C)Cc1ccccc1NC(=O)c1cnn(C)c1C +Cc1cccc(CC2(c3ccc(F)cc3)NC(N)=NC2=O)c1 +O=C(NCc1cc(-c2ccccc2F)on1)c1c[nH]c2ccccc12 +Nc1nc(SC2CCN(c3c(F)cccc3F)C2=O)n[nH]1 +Cn1cc(CCC(=O)OCc2ccc(Cl)cc2Cl)cn1 +O=C(CN1CCOC1=O)N1CC2c3ccccc3OCC2(CO)C1 +COC(=O)c1ccc(C(=O)N2CCOCC2(C)C)cc1 +NC(=O)c1cccc(OS(=O)(=O)N2CCCCCC2)c1 +Cc1ccc(SCC(=O)Oc2ccc(-n3cnnn3)cc2)cc1 +CCCn1c(NCC(C)C)nc2c1c(=O)n(C)c(=O)n2C +COc1ccc(-c2ccc(C#N)c(N3CCCC3)n2)cc1F +O=C(Nc1ccc(C(=O)N2CCCS2(=O)=O)s1)c1ccco1 +COC(=O)c1c(-c2csc(-c3ccco3)n2)c(C)n(C2CC2)c1C +CCc1nn(Cc2nc(-c3ccsc3)no2)c(=O)c(C#N)c1CC +CCn1ccnc1C(O)(c1ccccc1)c1ccccc1 +COc1ccc(SC(C)C(=O)NCC2CN(C)CCO2)cc1 +CC(C)CN(CC(F)(F)F)C(=O)c1ncn(-c2ccccc2)n1 +CCCn1c(C)nnc1SCC(=O)N(C)C1CCC(C)CC1 +Cc1ccc(CNC(=O)N2CCC(CN3CCOCC3)CC2)cc1F +Cc1cc(Br)cnc1NCc1n[nH]c(=O)[nH]1 +CN(CCCNc1nc2ccccc2c(=O)[nH]1)CC(F)(F)F +CCOC1CCCN(C(=O)c2ccnc(F)c2)C1 +NC(=O)C1Cc2ccccc2CN1Cc1nc(C2CC2)no1 +COc1ccc(C(=O)Nc2nc[nH]n2)cc1Br +CC(=O)N(CCc1ccccc1)CC(=O)N1CCOC(C)(C)C1 +CN(C)c1cc(C(=O)Nc2ccc(C(N)=O)cc2)ccn1 +CCOC(=O)CN(C(=O)Cc1ccc(Cl)cc1Cl)C1CC1 +CC(C)c1ccnc(NC(C(=O)N(C)C)C(C)C)n1 +Cc1nc(-c2nn3c(-c4cc(F)ccc4F)nnc3s2)co1 +CCC1COCCN1C(=O)c1cc(=O)c(OC)co1 +Cc1ccc(NC(=O)Cc2nn(C)c(=O)c3ccccc23)cc1 +Cc1nc(NC(=O)NC(C)C(=O)N2CCCC2)oc1C +O=C(NCc1cccs1)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +CC(C)CS(=O)(=O)NCC1(Sc2ccccc2)CCOCC1 +COc1ccc(C(O)CNc2ccc(Cl)cc2)cc1 +N#Cc1cc(F)ccc1Cn1cnc2c(nnn2-c2ccccc2)c1=O +CCOc1ccc(-c2ccc(=O)n(C(C)C(=O)N(C)C)n2)cc1 +Cc1cc(C)cc(NC2C(=O)Nc3ccc(F)cc32)c1 +COCCN1CCN(C(=O)c2ccc3ncccc3c2)CC1=O +COCCNC(=O)CNC(=O)c1cc(SC)ccc1C +CCc1nnnn1Cc1cc(-c2cccs2)on1 +O=C(COCC1CC1)N1CCCC(c2nc3ccccc3[nH]2)C1 +CCN1CCN(C(=O)C(C)Oc2ccc(Cl)cc2C)CC1 +O=C(Cn1nc(-c2ccc(Cl)cc2)ccc1=O)Nc1nncs1 +CCNC(=O)CNC(=O)c1c(F)cc(Br)cc1F +Cc1noc(C)c1S(=O)(=O)NC(C#N)C(C)C +COc1cccc(OCC(=O)Nc2ccc(-c3nncn3C)cc2)c1 +Cc1cc(C)n(-c2ccc(CSc3nnc(N)n3C3CC3)cc2)n1 +COc1ccc(C(=O)N(C)C2CCCCC2)c(O)c1 +Cn1c(Oc2ccc(Cl)c(Cl)c2)cc(=O)n(C)c1=O +O=C(NC(c1ccccc1)c1ccncc1)c1cc(C2CC2)[nH]n1 +CSc1nnc(COc2ccccc2Cl)o1 +CC(C)CC1(C(=O)CNc2ccc(Cl)cn2)CCC(=O)O1 +Cc1nc(C(=O)OCc2cc(-c3ccc(F)cc3)on2)cs1 +COc1ccc2nc(SCc3ccccc3N)[nH]c2c1 +CC(=O)NC(C(=O)N1CCN(C(=O)N(C)C)CC1)C(C)C +CCOc1ccc(C=Cc2nc(-c3ccc(C#N)cn3)no2)cc1OC +CCCCNC(=O)Nc1c(C(=O)OCC)[nH]c2ccccc12 +Cc1cnc(C(=O)N2CCC3(CC2)CC3C(=O)NCC2CC2)cn1 +COc1ccccc1CNC(=O)c1sc(C(C)C)nc1C +CNc1nc(-c2cc3c4c(c2)CC(=O)N4CCC3)cs1 +COCCNc1ccc(-c2nc(Cc3ccc(F)cc3)no2)cn1 +CCNC(=O)CN1CCN(C(=O)NCCCOC)CC1 +Cc1cc(C(=O)N2CCOc3cc(F)ccc32)c(C)o1 +COC(=O)c1cc(OC)cc(Br)c1N +CC(C)NC(=O)CNC(=O)CCc1ncc(-c2ccc(Cl)cc2)o1 +Cc1sc2ccccc2c1C(=O)CN1CCOCC1 +Cn1cnnc1SCCCC(=O)Nc1ccccc1N +CCn1cnnc1CNC(=O)c1cc(Cl)c2c(c1)OCO2 +CCCNC(=O)Cn1nnc(CO)c1-c1cccc(F)c1 +Cc1cc(NC(=O)NC2c3ccccc3CC2O)no1 +CCOC(=O)c1c(NCc2ccccc2)n[nH]c1N +O=C(COc1ccccc1)N1CCCC(c2cnccn2)C1 +Cc1ccc(CC(=O)N(C)C(C)c2ccc(Cl)cc2)cn1 +COC(=O)C1=C(C)C(C(=O)COC(=O)c2ccc(O)cc2)=NC1C +COc1ccc(CNC2C(=O)Nc3ccc(C)cc32)cc1 +O=c1cc(CN2CCOc3ccc(F)cc32)[nH]c2ccnn12 +CC(=O)N1CCN(CCNC(=O)C2CC2c2cccc(C)c2)CC1 +CCCNC(=O)CCc1nnc2ccc(N3CCC(C)CC3)nn12 +COCCCn1ccc(NC(=O)NCc2cnn(C)c2C)n1 +COc1cc2[nH]c(=NC(=O)c3c(C)noc3C(C)C)[nH]c2cc1OC +CC1=C(C(N)=O)C(c2c(F)cccc2Cl)NC(=O)N1 +CSc1ccc(CNc2ncccc2CO)cc1 +Cc1cnccc1NC(=O)c1cc(F)c(Cl)cc1Cl +CC(=O)Nc1cccc(NCC(=O)NCc2cccc(Cl)c2)c1C +CCN(CC)C(=O)c1ccc(-n2cnc3ccccc3c2=O)cc1 +O=C(COc1ccccc1CO)NCCc1c(F)cccc1F +O=c1c(NCc2cccs2)nccn1-c1ccc(F)cc1 +CC(=O)NCCCCCC(=O)N1CC(C)OCC1C +Cc1noc(C)c1CC(=O)Nc1cccc(C(=O)N2CCOCC2)c1 +CN(C)C(=O)C1CC2CN(C(=O)Nc3ccc(Cl)cc3)CC1O2 +COCCN1CCN(Cc2cc(=O)c(O)co2)CC1=O +Cc1n[nH]c(C)c1C(C)CC(=O)NC1CC(C)OC(C)C1 +O=C(Cn1ccnc1)N1CCC2(CCCN(C3CCOCC3)C2=O)C1 +O=C(NC1CCC(O)CC1)c1cnn(Cc2ccccc2Cl)c1 +CCCCNC(=O)C1CCC(C)N(C(=O)c2csnn2)C1 +NC(=O)CCC(=O)N1CCCC(Nc2ccc(F)c(F)c2)C1 +O=C1C(=O)N(CC2CCCO2)c2c(F)cc(F)cc21 +CCOCCn1c(N2CCCCCC2)nc2c1c(=O)[nH]c(=O)n2C +CCOc1ccc(NC(=O)CNC(=O)C(C)c2cccs2)cc1 +Cn1cccc1C(O)CNC(=O)CCS(=O)(=O)c1ccccc1 +O=C1CC(C(=O)N2CCCC(n3cccn3)C2)CN1Cc1ccco1 +O=C(NC1c2ccccc2CC1O)C1CC1c1c(F)cccc1Cl +Cn1c(=O)n(C)c2cc(NC(=O)NCc3cccc(Cl)c3)ccc21 +O=C(c1csc2ccccc12)N1CCC(n2ccnn2)CC1 +Cc1ccc2c(c1)CCCN2C(=O)c1ccc(N2CCCC2=O)cc1 +O=C(Nc1ccn(Cc2ccccc2)n1)NC1CCCc2occc21 +O=C(CSc1nccn1-c1cccc(Cl)c1)NC1CC1 +O=C(NCc1cccnc1)Nc1cc(F)ccc1N1CCCCC1 +CC(Nc1cccc(OCc2cccnc2)c1)c1nc(C2CC2)no1 +O=C(COc1ccc2oc3c(c2c1)CCCC3)NC1CCC(O)CC1 +Cc1ccc(NC(=O)CCc2nnc(N)n2N)cc1 +CCCCCc1nnc(NC(=O)Cn2c(=O)oc3ccccc32)s1 +CCCC(=O)N1CCCC(C(=O)NC2CC(OCC)C2(C)C)C1 +COC(=O)c1cc(C2CC2)nc2onc(-c3c(C)nn(C)c3C)c12 +OCC1CN(c2ccc(F)cc2)C(c2cccnc2)O1 +CCCCc1nnc(NC(=O)N2CCN(C(=O)N(C)C)CC2)s1 +COc1cc(C#N)ccc1OCCn1cnc2cc(F)ccc2c1=O +O=C(CNC(=O)c1cccs1)Nc1ccc(N2CCCC2)nc1 +COc1ccc(NC(=O)COc2nnc3ccccn23)cc1 +Cc1ccc(CNC(=O)CCC(=O)c2ccc3c(c2)CCC3)n1C +CCOC(=O)c1cccc(CN(C)C(=O)OC(C)(C)C)c1 +O=c1c2ccsc2ncn1CC(O)c1ccc(Cl)cc1 +CCCC(=O)n1nc(-c2ccccc2Cl)nc1N +CCc1onc(C)c1NC(=O)CNC(=O)c1cccc(F)c1 +CCCCN(C)C(=O)c1cc(-c2ccco2)nc2c1cnn2C(C)C +Cc1cccnc1NC(=O)c1ccc(OCC(F)(F)C(F)F)nc1 +COc1ccc(OC)c(CNC(=O)CNC(=O)c2ccc(C)cc2)c1 +Cc1cnc(C(=O)Nc2cccnc2N(C)C)cn1 +CCOc1ccnc(N2CCN(C(=O)CC3CCCO3)CC2)n1 +Cc1cc(C(=O)NC(C)C2CCCO2)c2c(=O)[nH]n(C)c2n1 +O=C(Cn1ccc2ccc(Cl)cc21)NCc1nnc2ccccn12 +Nc1c(C(=O)NC2CCCC2)nnn1-c1ccccc1 +Cc1noc(C2CCN(C(=O)NCCc3ccco3)CC2)n1 +Cc1nnc(NC(=O)CCOc2ccc(Cl)cc2)s1 +CC(C)c1ccc(NC(=O)CNS(=O)(=O)c2cn(C)cn2)cc1 +CCCC(C)N1CC2(CCN(C(=O)Cc3cc(C)no3)CC2)OC1=O +CCOc1ccc(C(O)CNC(=O)c2cccc(F)c2)cc1 +CCCS(=O)(=O)N1CCCCC1C(=O)NCc1cc(C)oc1C +COc1ccc(C2CC(C)N(C(=O)CCc3cn(C)nc3C)C2)cc1 +COc1ccc(F)cc1NC(=O)c1cnn(-c2ccccc2C)c1 +c1nc(C2CCC2)sc1CN1CCOCC1C1CC1 +CCOC(=O)c1cnc(SCCCC#N)nc1N +Cc1c(C(C)NC(=O)NCc2cccc(C#N)c2)cnn1C +Cc1ccc(C(=O)N(C)C)cc1NC(=O)CCn1c(C)csc1=O +CCS(=O)(=O)NC(C)c1cccc(N2CCOC2=O)c1 +CCC(=O)Nc1nnc(-c2ccc(S(=O)(=O)N(C)C)cc2)o1 +Cc1cc(F)ccc1NCC(=O)N(C)c1ccccc1 +C=CCSc1nnc2c(n1)OC(C)N(C(C)=O)c1ccccc1-2 +Cc1cc(C)c(NC(=O)NCCc2cnn(-c3ccccc3)c2)c(C)c1 +CC(NC(=O)CCc1ccncc1)c1cccc(N2CCOC2=O)c1 +CNC(=O)N1CCN(S(=O)(=O)c2cccnc2)CC1 +Cc1nc(C)c(C(=O)N(C)C(C)c2ccc(F)cc2)s1 +CNc1nc(CNC(=O)Nc2ccc(F)cc2C(F)(F)F)cs1 +Cn1nc2nc(NCc3ccccn3)nc(-c3cccc(F)c3)c2c1N +Cc1ccc(S(=O)(=O)N=c2ccc(N)c[nH]2)cc1C +CN(Cc1csc(C#CCO)c1)C(=O)c1ccsc1 +CCOC1COC2(CCCN(c3nncs3)C2)C1 +CCC(C(=O)NCCCOC)N1C(=O)CCCc2ccccc21 +CC(C)CC(=O)N(Cc1cccnc1)c1ccc(Br)cc1 +CCn1cc(S(=O)(=O)Nc2ccsc2C(=O)OC)cn1 +O=C(NCC1(N2CCOCC2)CCCCC1)c1ccncc1 +Cc1nnc(NCc2ccc(O)cc2Cl)s1 +CCOc1ccc(NC(=O)c2cccc(NC(C)=O)c2)cc1OC +CCCn1ncc(C(=O)NCCc2nc(C)c3c(n2)CCCC3)c1C +c1ccc(CSc2nnc(-c3cccnc3)o2)nc1 +Cc1cccc(OCC(=O)Nc2noc(-c3ccccc3)n2)c1 +COc1cc(OC)cc(C(=O)NCC(=O)N2CCCCC2)c1 +Cn1cnc(S(=O)(=O)NCC(=O)NC(C)(C)CC(C)(C)C)c1 +COc1cccc(C2CC(=O)Nc3[nH]nc(-c4ccccc4)c32)c1 +CC(C)c1nc2cc(-c3ncc(N)nn3)ccc2n1C +CC(OC(=O)C1CCC(C(C)(C)C)CC1)C(N)=O +Cc1c(O)ccc2c1C(C(O)c1ccccc1)NCC2 +O=S(=O)(NCC1CCCC1O)c1cc(F)c(F)c(F)c1 +CCCc1cc(C(=O)OC(C)C(=O)Nc2ncnc3nc[nH]c23)[nH]n1 +CCOC(=O)c1[nH]c(C)c(C(=O)Cn2c(C)csc2=O)c1C +COCCN(c1cc(N)cc(F)c1)C(C)C1CC1 +COc1cccc(CNc2ncnc3cc(OC)c(OC)cc23)c1 +Cc1noc(NC(=O)CSc2ccc(Cl)cn2)n1 +COc1ccc(C)cc1NC(=O)N1CCCC(CNC(=O)C(C)C)C1 +CCN1CC(C(=O)NC(C#N)c2cccc(Cl)c2Cl)CC1=O +Cc1cc(C)n2nc(C(=O)NCC3CCOC3)nc2n1 +CCCCN1C(=O)COc2ccc(NC(=O)c3snnc3C)cc21 +COC(=O)C(C)NC(=O)COc1ccccc1-c1ccccc1 +CC(C(=O)NCc1cccnc1)n1nc(-n2cccn2)ccc1=O +CN(CCCOc1ccccc1)C(=O)c1cnns1 +CCOc1ccc(NC(=O)Cn2c(=O)oc3ccccc32)c(C)c1 +CCn1nnc2cc(C(=O)NCCn3c(C)nc4ccccc43)ccc21 +COCc1ccccc1CNC(=O)Nc1c(C)cc(C)cc1C +COC(=O)CSc1cc(C(=O)NC2CC2)c2ccccc2n1 +Cc1cccc(O)c1NC(=O)CCc1cnn(C)c1C +Cc1ccc(CNS(=O)(=O)c2cc3c(cc2C)N(C)CCO3)cc1 +CCNC(=O)C1Cc2ccccc2N2CCN(c3ccccc3)CC12 +Cc1occc1C(=O)Nc1nc(CC(=O)N2CCCC(O)C2)cs1 +COc1ccccc1CNC(=O)c1ccc(F)cc1Br +Cc1ccccc1C1(O)CCN(Cc2cnc(N3CCCC3)nc2)C1 +Cc1noc2nc(-c3ccco3)cc(C(=O)N3CCC(O)C3)c12 +COc1cc2c(cc1OC)CCN(S(C)(=O)=O)CC2 +COc1cccc(C(=O)Nc2nnc(-c3ccccc3)s2)c1 +N#CCSc1ccccc1NC(=O)CN1CCOCC1C1CC1 +Cc1nc2ccc(NC(=O)N(C)CCCc3cnn(C)c3)cc2s1 +O=c1n(CCCNc2cncc(-n3cccn3)n2)nc2n1CCCC2 +NC(=O)C1CCN(C(=O)NCCc2ccc3c(c2)OCCO3)C1 +Cc1cccc(CNS(=O)(=O)c2cc(F)ccc2C)n1 +CS(=O)(=O)Nc1ccccc1CNC(=O)c1ccc(C#N)cc1 +O=C(Cn1cc(-c2ccc(F)cc2)oc1=O)NCc1ccccn1 +CC(=O)NC1c2ccccc2C2CN(C(=O)c3cnccn3)CC21 +Cc1nc(CN2CCN(C(=O)c3ccc4c(c3)CCCC4)CC2)no1 +CC(C)Cc1ncc2c(n1)CN(C(=O)c1ccc(=O)n(C)n1)C2 +OCCCn1nncc1-c1ccc2ccccc2c1 +CCCOCC(=O)Nc1[nH]nc(-c2ccncc2)c1CC +COc1ccc(CC(=O)NC2(C#N)CCOCC2)cc1 +CCC(=O)c1ccc(OCC(=O)N(C)Cc2ccc(F)c(F)c2)cc1 +Cn1cnc(S(=O)(=O)NCC(=O)N2CC(C)(C)C2(C)C)c1 +Cc1cc(NC(=O)c2scnc2C2CC2)n(-c2ccccc2C)n1 +CN(C)C(=O)c1ccc(CNC(=O)N(C)Cc2ccncc2)cc1 +O=C(Nc1ccc(S(=O)(=O)NCC2CC2)cc1)c1ccncc1 +CCCOc1ccccc1C(=O)N1CCC(CN2CCOCC2)CC1 +Cc1noc(CCC(=O)Oc2ccc3c(c2)OCO3)n1 +CCN(CC)C(=O)C1C(=O)N(CCO)C2(C)CC1c1ccccc1O2 +COc1ccc(NCc2ccc3c(c2)OCCO3)cn1 +COc1ccc(Cl)cc1NC(=O)NCC1(O)CCCC1 +COc1cccc2c(C)cc(=O)n(CC(=O)N3CCOCC3)c12 +N#CC(NC(=O)c1ccc(F)cc1)c1cccc(Cl)c1 +Cc1cccc(C)c1NC(=O)CNC(=O)C(C)N(C)CCC#N +COc1ccc(C(N)=O)cc1NCc1cc(-c2ccccc2)no1 +CCn1ncc(C(=O)Nc2cnn(CC)c2C(N)=O)c1C +CC(C)(C)Cc1nnc(NCc2ccsc2)o1 +COc1ccc(CN(C)C(C)CC#N)c(Cl)c1OC +COC1CCCCC1NC(=O)Cc1ccc(F)c(F)c1 +CNC(=O)NCC(=O)Nc1ccc(N(C)C)cc1C(F)(F)F +CCC(=O)N1CCCC(c2nnc(-c3cccnc3)o2)C1 +CCNC(=O)CNC(c1ccc(OC)cc1)C1CC1 +C(=Cc1nn2c(CN3CCOCC3)nnc2s1)c1ccco1 +CCCCN(C(=O)c1ccc2c(c1)OCO2)C(C)CC +CCc1ccc(CNC(=O)c2cccs2)s1 +CC(c1cccnc1)N(C)C(=O)NCCNC(=O)CC1CCCCC1 +Cc1cc(OCc2cccc(F)c2)ccc1NC(=O)c1cn[nH]n1 +CC(C)(CNC(=O)c1cccc2cn[nH]c12)N1CCOCC1 +Cc1cc(NC(=O)NCCc2nc(C)c(C)s2)c2ncccc2c1 +CNC(=O)Cc1ccc(NC(=O)c2ccccc2SC)cc1 +CCCN(C)c1ccc(-c2nc(-c3ccc(C#N)cn3)no2)cc1 +Cn1cnc(CNC(=O)c2cc(-c3cccs3)nc3ccccc23)n1 +Nc1ccc2c(c1)C1(OC2=O)c2ccc(O)cc2Oc2cc(O)ccc21 +O=C(NCc1nc(-c2ccccc2)no1)c1ccccc1Cl +COCC(C)N1CCN(C(=O)c2ccc(SC(F)F)cc2)CC1 +CC(=O)N1CCCN(C(=O)NCc2nnc3ccccn23)CC1 +CNC(=O)CNC(=O)CCc1ccc(Br)cc1F +CC(C)CNC(=O)c1csc2c1CCC(C)C2 +COc1cc(C#N)ccc1OC(=O)c1csc(C)n1 +Cn1cc(NC(=O)Nc2ccc(CCC(=O)N3CCCC3)cc2)cn1 +CC(=O)c1cccc(S(=O)(=O)N(C)C2CCC(C)(C)CC2)c1 +CC(NC(=O)C1CC(O)CN1C(=O)OC(C)(C)C)c1ccccc1 +CCn1cc(C(=O)NCCOc2ccc(OC)cc2)c2ccccc21 +CC(C)COCCC(=O)Nc1cc(-c2cccs2)n[nH]1 +Cc1ncc(C(=O)N2CC(C)(C)Sc3ccccc32)c(C)n1 +CC(Oc1ccc2c(c1)OCO2)C(=O)NC1CCCc2ccccc21 +CC(Sc1nc(N)nc(N)n1)C(=O)NCc1ccccc1 +COc1ccc(-c2cc(C(=O)NCc3ccco3)nn2C)c(OC)c1 +CCCN(CC(=O)OCC)C(=O)c1ccc(C)nc1C +O=C(NCCNC(=O)C1CC1)c1ccc(S(=O)(=O)C(F)F)cc1 +CC(=O)Nc1nc(C(=O)Nc2cc(F)cc(F)c2)cs1 +Cc1ccc(C(=O)Nc2ccccc2N2CCOCC2)cc1N +C=CCOCC12CCCOC1CCN(C(=O)c1cnccn1)C2 +N#CCCN(C(=O)CSc1ccc(F)c(F)c1)c1ccccc1 +Cc1nc(N2CCOCC2)nc(C)c1NC(=O)c1ccccn1 +C=C(C)COc1ccc(C(=O)NC2COCC2N2CCOCC2)cc1 +CCOC(=O)CN(C(=O)c1cccc(N)c1)C1CC1 +CC(C)c1nc(C2CCCN2C(=O)c2cn3cccnc3n2)no1 +O=C(Cc1c[nH]c2ccccc12)NCCCn1cccn1 +CCCCn1nc(C(=O)Nc2ccccc2O)ccc1=O +COc1cc(C)ccc1-c1ncncc1Br +CCN(CCn1nc2ccccn2c1=O)c1ccc(F)cc1 +COC1CCCC1OC(=O)CCc1ccc(F)c(F)c1 +COc1cc(CCNC(=O)c2cnn(-c3ccccc3)c2C)ccc1C +Cc1cccc(-c2noc(Cn3cnc4sc(C)cc4c3=O)n2)c1 +CC(O)CNC(=O)c1ccc(-c2cc(Cl)cc(Cl)c2)o1 +Cc1ccc(N)cc1NC(=O)C1COc2ccccc2O1 +CC(C)(C)c1ccc(C(=O)Nc2nnc(-c3ccno3)o2)cc1 +O=C(NCc1cccs1)c1cc(-c2cccnc2)[nH]n1 +CN(Cc1cc(F)c(F)cc1F)Cc1cccn1C +COCCOC(=O)Cn1ccc2ccc(Cl)cc21 +NC(=O)c1cnc(NC(=O)C(c2ccccc2)c2ccccc2)s1 +COC(=O)c1nnsc1NC(=O)CC1CCCCC1 +O=C1CCNc2ccccc2N1Cc1ccccc1 +CCOc1ccc(CN(C)C(=O)c2ccc3c(c2)CCC3)cc1OC +CC(CNC(=O)N(C)CC(F)F)Oc1ccccc1 +COC(=O)c1ccc(N(C(=O)c2ccncc2F)C(C)C)c(C)c1 +CCCC(NC(=O)CC)c1nc(-c2ccc3c(c2)OCO3)c[nH]1 +Cn1c(C(C#N)C(=O)CSc2ccncc2)nc2ccccc21 +Cc1ccc2ncc(C(=O)OCC(=O)NC3CCCCC3)n2c1 +Cc1cc(C)c(NC(=O)CSc2nnc3n2CCCCC3)c(C)c1 +CCN(CCNC(=O)c1csnn1)c1ccccc1C +CCOc1ccccc1CNC(=O)NC1CCN(C(C)=O)CC1 +CCCC1(CNC(=O)NCC2CN3CCCCC3CO2)CC1 +COc1c(C)cc(C(=O)N2CCCC(O)(CO)C2)cc1C +CCOc1ccc(NC(=O)NCc2cccc(C#N)c2)cc1C +Cc1cc(C)cc(NC(=O)Cc2csc(N3CCCC3=O)n2)c1 +CC(C)c1nc(Cc2nc3ccsc3c(=O)[nH]2)cs1 +O=C(Cn1cccn1)NCCCOC1CCCc2ccccc21 +Cc1ccc(NC(=O)c2nccc3cccc(N)c23)cc1 +CCC(=O)N1CCN(c2ccc(N3CCCC3)nn2)CC1 +CCCN(CCC)C(=O)CCn1cc(Br)ccc1=O +CCOCCC(=O)N(C)Cc1nccn1C(F)F +Clc1cc(Br)ccc1-c1cc[nH]n1 +Cc1nnc(NC(=O)C(C)n2nc(C(F)(F)F)cc2C)s1 +O=C(NCc1ccccc1)Nc1ccc(-n2cncn2)nc1 +CC(=O)Nc1cc(Cl)ccc1NC(=O)Cc1c(F)cccc1F +CCc1ccccc1NC(=O)Cc1ccc(NC(C)=O)cc1 +O=C(NCCC(=O)N1CCCc2cc(Cl)ccc21)c1cccs1 +Cc1cnn(CC2CC2)c1NC(=O)c1cccc(Cl)c1 +CCCn1c(C)cn2c3c(=O)n(CCC(=O)OC)c(=O)n(C)c3nc12 +CC(C)NC(=O)Nc1ccc(C(=O)Nc2ccc(N(C)C)nc2)cc1 +CC(=O)Nc1ccc(C(=O)CSc2nc3ccccc3s2)cc1 +CCN(CC)C(=O)c1ccc(NC(=O)CN(C)c2ccccc2)cc1 +Cc1nnc(-c2ccc(NC(=O)N3CCOCC3C3CC3)cc2)o1 +COCC(=O)NCC(C)Cc1ccc(OC)cc1 +CC(C)(C)c1nnc(NCc2ccc(C(=O)N3CCCCC3)cc2)o1 +O=C(NCC(C1CCOC1)N1CCOCC1)c1ccnnc1 +COCCOc1ccc(NC(=O)NCC2CCC2)cc1 +Cn1cc(NC(=O)c2cccnc2N2CCOCC2)cn1 +c1ccc2c(c1)CCN2CCn1cc(-c2ncc[nH]2)nn1 +CCC(NC)C(=O)c1cc(Br)ccc1OC +Cc1ccn2c(=NC(=O)c3cccc(S(C)(=O)=O)c3)[nH]nc2c1 +Cc1ccccc1CNC(=O)Cc1cn(C)c2ncccc12 +Cc1n[nH]c(C)c1C(C)CC(=O)NC(C)C(O)c1ccc(F)cc1 +CC(=O)Nc1ccccc1SCC(=O)N1CCNC(=O)C1C(C)C +C#CCOC(=O)Cn1c(=O)c2c(ncn2C)n(C)c1=O +NC(=O)NCC1CCCCN1c1cnc2cc(F)c(F)cc2n1 +COC(=O)Nc1ccccc1C(=O)N1CC=C(c2ccccc2)CC1 +Nc1ccc2c(c1)N(Cc1ccccc1F)C(=O)C(c1ccccc1)O2 +Cc1cc(C)nc(N2CCCC(c3ccnc(N)n3)C2)n1 +Cc1ccc2ncc(C(=O)OCCNS(C)(=O)=O)n2c1 +O=C(NCc1ccccc1)C1CC(=O)N(C2CCCCC2)C1 +Cc1ccc(NC(=O)COC(=O)C2CCC2)cc1Cl +COc1ccc2oc(=O)c(C(=O)Nc3cccc(C)c3)cc2c1 +Cc1ccc(F)c(C(=O)N2CCCC2c2ccncc2)c1 +Cc1n[nH]c(SCC(=O)Nc2cccc(C)c2C)n1 +CC1CN(CC(=O)NCc2ccccn2)c2ccccc2O1 +CC(O)CN1CCN(C(=O)c2ccc(CNC(N)=O)cc2)CC1 +Cc1noc(C)c1CCC(=O)N1CCC(OCC(C)C)CC1 +Cc1occc1-c1nnc(SC(C)C(=O)NC2CC2)n1N +CCCN(C)C(=O)c1cccc(OCC(N)=O)c1 +Cc1cc(C)nc(NC(=O)NCCCSc2nc(C)cc(C)n2)n1 +Cc1cccc(C(=O)N2CCN(C(=O)CCO)CC2)c1 +CCN(CC(=O)OC)C(=O)Nc1cccc(F)c1 +Cn1cc(C(=O)Nc2cccc(C#N)c2)ccc1=O +Cc1ccc(OCc2nnc3n(C)c(=O)c4ccccc4n23)c(C)c1 +c1csc(-c2nnc(NCc3cccc4cn[nH]c34)o2)c1 +O=C(NCc1nc(-c2cccs2)no1)c1ccccc1Cl +CC(C)(C)c1ccc(O)c(NC(=O)C2CC(=O)N(CC3CC3)C2)c1 +COC(=O)Cn1cnc2c(-c3ccc(F)cc3)csc2c1=O +CCOc1ccc(C(=O)Nc2cccc(F)c2C#N)cc1 +CC(C)CNc1nnc(-c2ccc[nH]c2=O)s1 +COc1ccc(C2=Nc3nnnn3C(c3ccccc3)C2)cc1OC +Cc1cc(C(=O)C2CCCN2S(C)(=O)=O)ccc1F +CC(CNC(=O)NCc1cc(=O)[nH]c2ccccc12)c1nccs1 +Cc1cc(-c2nc(-c3ccc(C#N)cn3)no2)c2c(C)nn(C)c2n1 +CCCn1c(SCC(=O)NCc2ccc(C)cc2)n[nH]c1=O +Cc1ccc(C)c(NC(=O)CNc2c(C)cccc2C(N)=O)c1 +CCC1CCC(NC(=O)Cc2cccc(OCC#N)c2)CC1 +NC(=O)c1cccc(NC(=O)COc2ccccc2-c2ccccc2)c1 +CCCC(NC(=O)C(C)Sc1nncn1C)c1ccccc1 +Cn1ncc2c1CCCC2NC(=O)NCCOc1cccc(F)c1 +Cc1nc(C2CCCN(C(=O)C(C)n3ccnc3)C2)sc1C +Cc1ccc2c(C)nc(N=C3NCN(C(C)C)CN3)nc2c1 +c1ccc2oc(N=C3NCN(CC4CCCO4)CN3)nc2c1 +COc1ccc(C(=O)C(C)CN2CCOCC2)c(OC)c1 +CN(C)c1ccc(Cl)cc1NC(=O)NC(C)(C)c1nccs1 +CC1COC(c2ccccc2Cl)CN1Cc1nnc(C2CC2)n1C +Nc1cnn(CCCc2cc(Br)cs2)c1 +COCCOc1cccc(CNC(=O)c2cc3c(F)cccc3[nH]2)c1 +CC(OC(=O)c1csc(-c2ccsc2)n1)c1ccccn1 +CCc1nn2c(C#N)c(-c3cc(OC)ccc3OC)nc2s1 +COc1ccccc1C(NC(=O)C1CCCO1)C(C)(C)C +COCCOc1ccc(NC(=O)NCc2ccccc2)cc1Cl +O=C(c1ccc(F)cc1)c1ccc(OCc2nnnn2C2CC2)cc1 +O=C(c1cccs1)N1CCc2nc3ncccc3cc2C1 +CC1CCOC1C(=O)NCCNc1cccc(F)c1C#N +O=C(CC(c1cccs1)n1cccc1)NCc1cccnc1 +CCCN(CC(=O)OCC)C(=O)c1cc(Br)cn1C +Cc1ccc(-c2ncc(C(=O)NCC3CC3)c(N(C)C)n2)cc1 +COc1ccc(C2NC(=O)c3cccc(C)c3N2)c(OC)c1OC +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)C1CCN(C(=O)C2CC2)CC1 +CCn1nccc1C(=O)Nc1nnc(Cc2ccc(C)cc2)o1 +CC(C)CNC(=O)c1nc2c(O)cccc2s1 +CCc1nnc(NC(=O)N2CC=C(c3ccccc3Cl)CC2)s1 +O=C(CCC1CCCOC1)Nc1ccc2c(c1)COC2 +O=C(NCCc1cnn(-c2ccccc2)c1)NCc1ccco1 +O=c1cc(CNc2ccccc2OC(F)(F)F)nc2sccn12 +COCCC1(C(=O)N2CCC(OC(C)(C)C)CC2)CCCC1 +CCc1nc(C(C)NC(=O)NCc2ccnc(OC)c2)cs1 +CCOC(=O)c1nn(-c2ccc(C)cc2)c2nnc(C)c(=O)n12 +O=C1CCCN1CCC1CCN(C(=O)C2CCc3ccccc32)CC1 +CS(=O)(=O)c1ccc(C(=O)NCCCC2CCCC2)cc1 +Cc1ccc(NC(=O)N2Cc3cnc(C(C)(C)C)nc3C2)cc1 +CCc1csc(C2CCN(C(=O)C3CCCC3)CC2)n1 +COC(=O)CN(C(=O)c1ccn(-c2ccc(OC)cc2)n1)C(C)C +CS(=O)(=O)c1ccc(-c2cccc(Br)c2)cc1 +CCOC(=O)c1cnc2c(ccc3ccccc32)c1NCC(C)O +Cn1c(SCC(=O)NCc2cccc(Cl)c2)n[nH]c1=O +Cc1cc(C)c2c(c1)OCCC2NCCCN1CCOCC1 +CCc1nc2n(n1)CCCC2NC(=O)N(C)Cc1ccc(OC)cc1 +CCC(C)c1cc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)on1 +Cn1cc(S(=O)(=O)N2CCCC(c3ccnc4nccn34)C2)cn1 +CCOc1cc2c(cc1CNC(=O)NCc1cscn1)OC(C)C2 +CCOc1ccc(S(=O)(=O)N2Cc3ccccc3C2)cn1 +O=C(COC(=O)c1cc(F)ccc1Br)C1=NC=CC1 +O=C(Nc1nnc(C(F)(F)F)s1)NC1CCC(O)CC1 +Cc1ccc(C(=O)NC(c2ccccc2F)c2nccn2C)cc1 +COc1ccc(F)c(NCC(C)(C)CCC#N)c1 +Cc1ccc(OCC(=O)c2cc(C)n(C3CC3)c2C)nc1 +Cc1ccc(CN(C)C(=O)COc2ccc(-n3cnnn3)cc2)o1 +C=CCN(C)S(=O)(=O)c1ccc(NC(=O)NCCC)cc1 +CCn1c(SCC(=O)N(C)CCC#N)nnc1-c1cccs1 +Cn1ccnc(NC(=O)c2ccnc3ccccc23)c1=O +CCOC(=O)C(O)c1nc2ccc(OC)cc2s1 +CC(C)OCc1c(C(=O)NCc2ccco2)oc2ccccc12 +CC(C)(C)c1ccc(NC(=O)c2cccc(-n3cccn3)n2)nn1 +COC(=O)NC(C)(C)C(=O)Nc1ccc(Cl)c(Br)c1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)c1cc(F)cc2[nH]cnc12 +CCOC(=O)N1CCCC(C(=O)Nc2cccc(Cl)c2F)C1 +CC(O)c1cn(C2CN(C(=O)C3(c4cccc(F)c4)CCC3)C2)nn1 +COc1ccc(-c2cc(C(C)C)nc(N)n2)c(OC)c1C +CN(Cc1ccccc1N)C(=O)c1cc2ccccc2o1 +C=CCN1C(=O)C2(OCCO2)c2c(Cl)ccc(Cl)c21 +Cc1ccc(-c2nnc(NC(=O)c3ccnn3C)o2)c(C)c1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCc1ccco1 +CCn1nc(NC(=O)c2cc3ccc(F)cc3[nH]2)cc1C +CCCc1c(C(=O)Nc2ccc(F)cc2F)[nH]c(C)c1C(=O)OC +COC1CCN(C(=O)c2n[nH]c3ccccc23)CC1 +CS(=O)(=O)NC1CCN(C(=O)CSc2ccc(F)cc2)CC1 +CCc1ccc(NC(=O)N(C)Cc2cc(C(=O)OC)c(C)o2)cc1 +Cc1c(C(=O)NCCCc2ccccc2)cnn1-c1ccncc1 +COc1cc(CNc2ccc(NC(C)=O)cc2)cc(Cl)c1O +Cc1ncsc1CNC(=O)N(C)CCN(C)C(=O)OC(C)(C)C +CCC(NC(=O)N(C)Cc1c(C)noc1C)c1cc(F)ccc1F +Cc1cccc(OCc2nnc(SCc3noc(C(C)C)n3)o2)c1 +CC(CC#N)N(C)C(=O)Nc1ccc2c(c1)OC(C)(C)O2 +O=C(NCc1cccnc1)c1cc(Br)c2c(c1)OCCO2 +CCOc1cc2c(cc1NCc1noc(C(C)C)n1)OC(C)C2 +COc1cccc2c(=O)c(C#N)cn(Cc3cccc(F)c3)c12 +COc1cccc(NCC(=O)c2cc(F)ccc2OC)c1 +CCC(CC)N(C)S(=O)(=O)c1ccc(C)cc1N +CNC(=O)c1cc(-c2ccccc2)nc2ccccc12 +Fc1cccc(-c2nnc3sc(Cn4ccnc4)nn23)c1 +Cc1ccc(NC(=O)NCc2nn(C)c(=O)c3ccccc23)cc1 +O=C(OCC1CCCO1)c1csc(-c2cccs2)n1 +Cc1cnn(Cc2cc(C(=O)NCc3csc(=O)[nH]3)no2)c1 +CC1CC(C)CN(C(=O)Nc2cccc(C(N)=O)c2)C1 +O=C(NCc1ccccc1-n1ccnc1)Nc1cc(F)cc(F)c1 +Cc1cc(C)n(CCCNC(=O)c2cncc(Br)c2)n1 +CC(Sc1nccn1C)c1nc(-c2nc[nH]n2)no1 +O=C(c1ccsc1)N1CC2CCN(CC3CC3)C(=O)C2C1 +CN1c2cc(C(=O)NC3CCCCC3)ccc2C(=O)N2CCCCC21 +Cc1nn(CCc2nnc(-c3cc(F)ccc3F)o2)c(C)c1Cl +CC(C)c1nc(-c2ccc3c(c2)CCCN3)nn1C +COc1ccc(-c2c(C(F)(F)F)noc2N)cc1F +C#CCCNC(=O)Cn1cnc2ccccc2c1=O +COc1ccc(OC)c(NC(=O)c2nc3ccccc3n(C)c2=O)c1 +CCCOc1ccc(CNC(=O)Cn2cc(Cl)cn2)cc1 +Cc1ccc(NC(=O)c2c(F)ccc3cn(C)nc23)cc1C +NC(=O)C1CCN(S(=O)(=O)c2cccc(O)c2)CC1 +COc1cc(OC)cc(C(=O)Nc2ccccc2OC)c1 +CCC(OC)C(=O)Nc1cc(C(N)=O)cc(F)c1C +CNC(=O)C(C)NC(c1ccc(F)cc1)C1CC1 +Cc1ncc(CNC(=O)NC(C)CCC(C)C)s1 +CCCN(CCO)C(=O)Nc1cc(Br)ccc1C +Cc1ccc(SCC(=O)c2ccc3c(c2)NC(=O)CO3)c(C)c1 +CC(C)NC(=O)C1CCCN(c2nc3cccnc3s2)C1 +COc1c(Cl)cccc1NCc1nc(C)no1 +Cc1cc(-c2nnn(CC(=O)NC3(C#N)CCCC3)n2)ccc1F +CC(=O)Nc1ccc(S(=O)(=O)Nc2cccc(Cl)c2)cc1 +COc1ccc(S(=O)(=O)Nc2cccn(C)c2=O)c2ccccc12 +CC1(NC(=O)C2CCN(c3cnccn3)CC2)Cc2ccccc2C1 +CCn1cc(NC(=O)c2ccccc2S(=O)(=O)C(C)C)ccc1=O +COc1ccc(N(C(=O)C2CC2)S(=O)(=O)c2ccccc2)cc1 +O=C(NCCNC(=O)c1cnc2ccoc2c1)c1ccc(Cl)cc1 +COC(C)(C)c1noc(C2Cc3cccc(F)c3O2)n1 +CCCNC(=O)CCNC(=O)c1ccnc(NC)c1 +NC(=O)Cn1ccc(NC(=O)C2(c3cccc(Cl)c3)CC2)n1 +Cc1nc(C)c(C#N)c(SCc2nc3ccccc3n2C(F)F)n1 +CCc1nc(CC(=O)Nc2ccccc2C(=O)NC(C)C)cs1 +CCC(Oc1cccc(N)c1)C(=O)OCC(C)C +COCC(=O)NC(C)c1nc2ccccc2n1CC(N)=O +CCS(=O)(=O)NCC(=O)N1CC2(CCCC2)c2c(F)cccc21 +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)NCC(C)O +C=CCNC(=O)C(C)Sc1nccn1-c1cccc(C)c1 +C=CCNC(=O)CSc1ccc(S(C)(=O)=O)cc1 +NC(c1nnc(-c2c[nH]cn2)o1)c1c(F)cccc1F +C=CCSc1ccccc1C(=O)Nc1ccccc1NC(C)=O +CC(Cc1ccccc1)NCc1cccc(C#N)c1 +CCOc1ccc(Cl)c(C(=O)NCc2cccnc2)n1 +CCOc1ccccc1CNC(=O)c1cc(OC)ccc1O +Cc1cc(C(=O)N2CCc3sccc3C2)ccc1N +COc1ccc(Cl)cc1N1CCC(NC(=O)CNC(N)=O)C1 +COc1ccccc1CC(=O)Nc1nnc(CC(C)C)s1 +COc1cccc(-c2cnnc(N3CC(C)OC(C)C3)n2)c1 +Cc1nn(C)cc1S(=O)(=O)NCC1(c2ccccc2)CCOCC1 +COC(=O)c1cc(=O)c2c(C(F)(F)F)ccc(C)c2[nH]1 +CCOc1ccc(OCC)c(NC(=O)c2cn[nH]n2)c1 +Cc1cc(C)n(CCCNC(=O)c2c(Cl)cccc2Cl)n1 +O=C(NCCC1=CCCCC1)c1nnc(-c2ccc3c(c2)OCO3)o1 +CC(C(=O)NCCNC(=O)c1ccc(Cl)cc1)c1cccs1 +COc1cccc(NC(=O)Nc2nnc(N3CCCC3)s2)c1 +Cc1noc(C)c1S(=O)(=O)Nc1cccc2c1CCCC2 +O=C(NCc1ccc(F)cc1)c1nnc(COc2ccccn2)s1 +COc1cc2c(cc1OC)C(C)N(C(=O)COc1ccccc1)CC2 +Cc1cc(F)ccc1C(=O)N1CC(CO)OCC1C +CCSc1cc(C(=O)N2CCCC2c2cc(C)no2)ccn1 +CC1CN(Cc2ccccc2)CCN1Cc1nnc(C2CC2)n1C +Cn1cc(S(=O)(=O)Oc2ccccc2C(F)(F)F)cc1C(N)=O +CC(OC(=O)C1Cc2ccccc2C(=O)O1)c1ccccn1 +COc1cccc(-c2nc(C(=O)NCC3(CO)CC3)c(C)[nH]2)c1 +CCn1cc(C(=O)N(C)CCC2CCCCC2)cn1 +Cc1ccn2cc(C(=O)NCc3ccoc3)nc2c1 +CN(C)c1cccc(C(=O)Nc2cccc(-c3nnnn3C3CC3)c2)c1 +Cc1cc(C)cc(C(=O)NCc2cc3ccccn3n2)c1 +Nc1ccc2nn(-c3cccc(C(F)(F)F)c3)nc2c1 +CCCOc1ccc(Cl)cc1NC(=O)C1CC(=O)N(C)C1 +CC(C)(C)OC(=O)NCCCC(=O)Nc1cc(F)cc(F)c1 +Cc1cc2nnc(SCC(=O)N(C)C3CC3)n2c(C)n1 +OCc1nnn(Cc2ccc(Cl)cc2)c1-c1cccnc1 +CCOC(C)c1noc(Cn2nc(-c3cccs3)oc2=O)n1 +O=C1CC(c2cc(F)c(F)c(F)c2)c2c(nc3ccccn3c2=O)O1 +O=C(c1c[nH]c2cccc(F)c12)N1CCN(c2nccs2)CC1 +CCNC(=O)c1snc(-c2ccc(Cl)cc2)c1N +CC(C)C(=O)NCCC(=O)Nc1ccc(F)cc1 +CN(C)S(=O)(=O)N1CCN(CC2CCCCO2)CC1 +COc1cc(OC)c(NC(=O)c2cc3cc(F)ccc3[nH]2)cc1Cl +CCN(CC(=O)NC(C)(C)C)C(=O)CNC(=O)c1ccccc1 +Cc1ncc(CNC(=O)NCc2nc(C)c(C)o2)s1 +CNc1nc(C(=O)N2CCCC(CO)(CCCOC)C2)cs1 +O=C(COc1ccc2c(c1)CCC(=O)N2)Nc1cn[nH]c1 +COC(=O)CCCn1cnc2c(Br)cccc2c1=O +O=C(C1CC=CCC1)N1CCC2CC(c3nnc(C4CC4)o3)OC2C1 +CC(C)(C)OC(=O)NC(C)(C)C(=O)NCC(C)(C)C(N)=O +COCCN1CCCC2(CCN(C(=O)c3cc[nH]c3C)C2)C1=O +Cc1ccc(-n2nc(C(=O)NC(C)C)nc2-c2ccoc2)cc1 +Cc1occc(=O)c1OCC(=O)NC1CCCC1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)c1cccn1C +Cn1c(N2CCCN(C(=O)c3ccco3)CC2)cc(=O)n(C)c1=O +COc1cccc(OCc2noc(-c3cc(OC)cc(OC)c3)n2)c1 +Cc1ccc(C(=O)N2CCC3(O)CCCCC3C2)cc1-n1cnnn1 +CCC(C)c1ccccc1N1CC(C(=O)NCCO)CC1=O +Cc1ccc(N2CCCC2=O)c(C(=O)N2CCOC3CCCCC32)c1 +O=C(CNC(=O)c1ccoc1)Nc1cnc2ccccc2c1 +CC(C)OCCCNC(=O)c1cnn(C)c1-n1cccc1 +O=C(Cn1c(=O)cnc2ccccc21)NCc1ccccc1Cl +Cc1nc(S(=O)(=O)NCCC(=O)N2CCCC(C)C2)cn1C +Cc1occc1C(=O)Nc1cccc(C(=O)c2ccccc2)c1 +O=C(NCC(=O)N1CCC(c2ccccc2)CC1)c1cccs1 +COc1ccccc1C(=O)NC(CO)CC(C)C +Nc1nnc(-c2cn(-c3ccccc3)nc2-c2ccccc2)o1 +CC1CCc2ccccc2N1C(=O)Cn1nc(-c2ccco2)oc1=O +CC(C)Cc1cc(Br)c2c(c1)NC(=O)CO2 +Cc1cc(C(=O)N2CCNC(=O)C2CCO)c(-c2ccccc2)o1 +CC(=O)Nc1n[nH]cc1C(=O)NCc1ccc(C)cc1 +N#Cc1cccc(NC(=O)N2CCC(CCn3cccn3)CC2)c1 +COc1ccc(OCCCc2nn3c(C#N)c(C)nc3s2)cc1 +COC(=O)CN1CCC(c2nc3ccccc3o2)CC1 +COC(=O)c1cc(C)sc1NC(=O)CSc1nccc(C)n1 +Cc1nn(C(C)C)c(C)c1NC(=O)CN1CCc2sccc2C1 +Cc1cc(C(=O)N2CC(OCc3cccnc3)C3COCC32)c(C)o1 +Cc1ccc(F)cc1NCc1cc(=O)n2c(C)csc2n1 +COc1ccc2c(ccn2CC(=O)Nc2ccc3cc[nH]c3c2)c1 +CN(CCC(F)(F)F)C(=O)Cn1ccc(=O)n(C)c1=O +O=C(CSc1nc(-c2ccccc2)c[nH]1)NC1CCCC1 +COc1ccc(C(C)=O)cc1CC(=O)Oc1ccc(F)cc1 +CCC(C)n1nccc1NC(=O)C1CCCN(C(=O)NCC(C)C)C1 +CC(C)(C)c1ccccc1OCCNC(=O)CC#N +COCCNC(=O)N1CCC(Cc2ccccc2)CC1 +O=C(c1cc(-c2cccs2)n[nH]1)N1CCC2(CC1)OCCO2 +CCOc1ccc(C)cc1-c1nc2c(CO)cccn2c1N +Cc1cccc(C(=O)N2CCc3sccc3C2)c1N +Cc1ccc(C(=O)Nc2cccc(Cl)c2N(C)C)n1C +Cc1ccc2c(c1)N(C(=O)c1ccn(C)c1)CCC2 +C#Cc1cccc(N(C(=O)COc2ccc(C(C)=O)cc2)C(C)C)c1 +Clc1cc(Br)cnc1NCc1ccccn1 +Cc1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)c(O)c1 +Cc1cc(F)ccc1NC(=O)CC(NC(N)=O)c1ccccc1 +N#Cc1ccc(CSc2nnc3ccccn23)c(F)c1 +C#CCNC(=O)c1cc(C2CC2)nn1-c1ccccc1 +Cc1nc(Sc2nnnn2C2CC2)c2c3c(sc2n1)CCC3 +Cc1ccc(COC(=O)c2n[nH]c(=O)c3ccccc23)cc1 +COc1cc(C(=O)N2CC3CCC2CN(C(=O)C2CCC2)C3)ccn1 +O=C(NCC1CN2CCCCC2CO1)c1ccc(-c2ncon2)cc1 +Cc1ccc(C(=O)CCC(=O)OCC2CCCO2)cc1C +COc1cccc2c1N(Cc1oc(=O)oc1C)CCC2 +Cc1ccc(OC2CCN(C(=O)Cc3cccs3)CC2)cn1 +CC1=CCC(CN(C)C(=O)CCc2c[nH]c3ccccc23)O1 +COC(=O)c1ccccc1N(C)C(=O)c1cccc(C#N)c1 +COc1ncccc1NC(=O)NCC(C)N(C)c1ccccc1 +Cc1c(C(=O)N(C(C)C)C2CC2)nnn1-c1ccc2ncccc2c1 +CCOC(=O)C1CCC(=O)N1c1ccc2c(c1)OCCO2 +CCN(CC(C)C#N)C(=O)c1cccc(N(C)C)c1 +Cc1cnn(CCC(=O)NCCc2ccccc2)c1 +Cc1ccc(O)c(NC(=O)c2ccc(C#N)c(C)n2)c1 +COc1ccc(NC(=O)c2cc(=O)c3ccccc3o2)cn1 +c1csc(-c2noc(CSc3ccc4c(c3)OCCO4)n2)c1 +COc1ccc(F)cc1NC(=O)NC1CCc2c(O)cccc21 +O=C(CNC(=O)c1cnc2ccoc2c1)Nc1ccc(F)cc1 +O=C(Cn1cnc2c(oc3ccccc32)c1=O)Nc1cccc(F)c1 +COC(=O)c1coc(C(=O)N(CC(F)(F)F)C(C)C)c1 +Cc1nn(C)c2ncc(S(=O)(=O)N(C)CCOCC3CC3)cc12 +CCOc1cccc2cc(S(=O)(=O)N3CCCC3)c(=O)oc12 +CC(=O)Nn1ccc2c(cnc3nc(-c4ccncc4)nn32)c1=O +Cn1nc(C(=O)OC(C(N)=O)c2ccccc2)c2ccccc2c1=O +O=C(CCN1C(=O)CCc2ccccc21)Nc1cc(F)ccc1Cl +CC(NC(=O)Nc1cn[nH]c1)c1cc2ccccc2o1 +O=C(c1ccc(Cl)cc1)N1CCCCCC1c1ccncc1 +COc1ccc(C(C#N)N(C)C(=O)OC(C)(C)C)c(OC)c1 +CCC(=O)N1CCC(C(=O)Nc2ccn(-c3ncccc3Cl)n2)C1 +COc1ccc(C(=O)CCCO)cc1C(C)(C)C +CC(CN1CCCC1=O)NS(=O)(=O)c1ccc(F)cc1 +CCCCn1nccc1NC(=O)Cn1ncc(N2CCCC2)cc1=O +CCCCCOc1cccc2c1CCNC2c1ccnnc1 +Cc1sc(-c2nnc(C(C)C)o2)cc1NC(=O)c1ccccc1 +O=c1ccc(-c2ccc(S(=O)(=O)NCc3cccs3)o2)n[nH]1 +Cc1ccc(-c2nnc3n(C)c4c(=O)n(C)c(=O)n(C)c4n23)cc1 +CC(NC(=O)Nc1cccc(S(N)(=O)=O)c1)c1ccncc1 +CCCn1nc(-c2ccc(OC)c(CC)c2)cc(C#N)c1=O +O=C(NCC1CCCCC1)c1ccc2c(c1)OCCO2 +Cc1ccc2nc(NC(=O)c3cc(N)ccn3)sc2c1 +CCCc1c(C#N)nnn1-c1ccc(Cc2ccncc2)cc1 +Cc1nc2cc(-c3cnn(-c4ccccc4)c3)ccc2c(=O)[nH]1 +COCc1nc(C)c(C(=O)N(C)c2ccccn2)s1 +O=C(CC1OCCc2ccccc21)Nc1nncs1 +CCOc1cc(C(=O)Nc2ccccc2N2CCCC2)ccc1OC +CN(C(=O)CCOc1ccccc1)C(C#N)c1ccc(F)cc1 +COc1cccc(C(=O)NCCNC(=O)c2ccc(C)nc2)c1 +N#Cc1cc(F)c(NCCC(=O)N2CCOCC2)c(F)c1 +CCN(C(=O)c1ccncc1)C(c1cccnc1)c1ccc(F)c(C)c1 +O=C(NCCc1ccccc1)c1ccc(Cn2cnnn2)cc1 +CC(=O)c1nnn(-c2ccc3c(c2)OCC(=O)N3C)c1C +COc1ccccc1CC(=O)Nc1cc(S(C)(=O)=O)ccc1F +Cc1noc(CNS(=O)(=O)c2cc(F)cc(F)c2)n1 +CCn1cc(C(=O)Nc2cccc(C(F)(F)F)c2)c2cccnc21 +CCOC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1ccc(C)cc1 +C=CCNS(=O)(=O)c1ccc(C(=O)N(C)Cc2ccc(C)o2)cc1 +C=CCSc1nnc2n1-c1sc3c(c1-c1ncnn1-2)CCCC3 +Cc1n[nH]cc1CN(C)Cc1nc(-c2cccnc2)no1 +CNc1snc(C)c1C(=O)Nc1ccc(F)c(Cl)c1 +Cc1nc(C(=O)N2CCCC(CNS(C)(=O)=O)C2)cs1 +O=C(CNC(=O)NCc1ccc(Cl)cc1)Nc1ccccn1 +CCCCn1c(S(=O)(=O)Cc2noc(C(C)C)n2)nc(C)c1C +O=C(Cc1ccc2ccccc2c1)NCC1CCCO1 +O=C(CCn1cc(Br)cn1)Nc1ccncc1 +O=C(c1cc(Br)cs1)N1CCC(O)CC1 +CCOC(=O)CN(C)C(=O)c1scnc1C1CC1 +Nc1ccccc1Cc1nn2cnnc2n(CCO)c1=O +CN(Cc1ccc(F)cc1Cl)Cc1cnnn1C +CCn1nccc1NC(=O)COc1ccccc1OC +O=C(c1cn2ccsc2n1)N(Cc1ccc2[nH]ccc2c1)C1CC1 +NC(=O)C1(NS(=O)(=O)c2c[nH]cn2)CCCCC1 +COC(=O)C1CCCCN1C(=O)c1cc(C2CC2)nc2onc(C)c12 +CC(C)C(=O)NC1CCCc2c1cnn2C(C)(C)C +CC(Sc1nnnn1C1CCOCC1)c1nc2ccccc2o1 +Cc1ccn(CCC(=O)N2CCc3ccccc32)n1 +CNc1nc(-c2nnc3sc4c(n23)CCCC4)cs1 +CCc1ccc(C2CC(=O)Nc3nc(N4CCOCC4)nc(N)c32)o1 +CC(=O)NC(C(=O)NCC(O)c1ccccc1C)C1CCCC1 +CC(=O)c1c[nH]c(C(=O)Nc2nc(C)c(-c3ccccn3)s2)c1 +CC(NC(=O)N(C)Cc1cc(Cl)cn1C)c1cccnc1 +CC(=O)NC(C(=O)OCCc1cccnc1)C1CCCC1 +CNC(=O)NCC(=O)Nc1ccc(C(C)N2CCOCC2)cc1 +CSc1ccccc1NC(=O)Cc1n[nH]c2ccccc12 +COc1ccnc(Sc2nnc(-c3cccs3)n2C2CC2)n1 +CC(C)c1ccccc1NC(=O)c1ccc2ccnn2c1 +Fc1ccc(-c2nnc(C3CC3)o2)cc1Br +Cc1ccccc1COC1CCN(C(=O)NCc2cscn2)CC1 +CCc1cc(N)cc2c(=O)cc(C(=O)N(CC)CCO)oc12 +CNC(=O)c1ccc(NC(=O)NCc2cnn(C)c2C)c(C)c1 +Cc1cc(C)n(C(C)C(=O)Nc2ccccc2N)n1 +CCC(CC(=O)N=c1[nH]ncn1C)c1ccccc1 +CC(C)C(NC(=O)c1ccc(Cl)cc1)C(=O)OCC(N)=O +CN1C(=O)c2ccccc2NC1c1cccc(O)c1 +CCN(CC)C(=O)Nc1ccc(C)c(N2CCCS2(=O)=O)c1 +COc1ccccc1C(NC(=O)NCC1CCCO1)C(C)(C)C +Cc1ccsc1CN(Cc1cccc(C#N)c1)Cc1ccccn1 +Cc1ccc(C(N)=O)cc1NC(=O)CCNC(N)=O +CC1NCc2ccccc2C1C(=O)NC1CCCCC1 +Cc1ccc(CNC(=O)CNC2=NS(=O)(=O)c3ccccc32)s1 +CCc1nc(NC(=O)c2cccc(N3CCCNC3=O)c2)sc1C +N#Cc1cnn2c(C(F)F)cc(-c3ccc4c(c3)OCO4)nc12 +Cc1ccc(CNS(=O)(=O)c2cnc(N)nc2)cc1 +CC(CCCO)NS(=O)(=O)Cc1ccccc1Cl +CCc1ccc(C(=O)NCc2ccc(CC)s2)o1 +COc1ccc(CCC(=O)NCC(C)(C)C(N)=O)cc1F +CCOC1COC2(CCN(C(=O)c3cccc(C)n3)CC2)C1 +CCN(CC)C(=O)N1CCCC(C(=O)NCCc2ccc(F)cc2)C1 +Cn1c(=O)n(C)c2cc(NC(=O)Nc3ccc(F)cc3)ccc21 +O=C(NCCOc1ccc(Cl)cc1)c1ccccc1 +Cc1cc(N2CCN(c3cccc(Cl)c3)CC2)n2cnnc2n1 +CC(C)CNC(=O)Cn1nc(C#N)cc1-c1cccs1 +O=C1CCCN1c1ccc(CNc2nnc(C3CC3)o2)cc1 +CC(C)n1cc(S(=O)(=O)N2CCC(n3cccc3)CC2)cn1 +Cc1nccc(CNc2cnn(-c3ccccc3)c(=O)c2Cl)n1 +COc1ccc(CN2CC(C(=O)N(C)CC3CC3)CC2=O)cc1 +c1cc(OCC2CCCO2)ccc1CN1CCOC2(CCC2)C1 +Cc1cc2cc(C(=O)c3cc(C(N)=O)co3)oc2cc1C +O=C(CCCc1nc(C2CC2)no1)N1CCCC(c2ccn[nH]2)C1 +C=C(C)COCCNC(=O)NCc1ccnc(C)n1 +O=c1[nH]cnc2c(-c3ccc(Br)cc3)csc12 +CN(C)c1nc(N)nc(COc2ccc3ccccc3c2)n1 +CC(COC1CCOC1)NC(=O)c1ccc(-n2ccnn2)cc1 +CC(C)N(C(=O)Cn1nnnc1C(C)(C)C)C1CCCC1 +CC(=O)NCCCC(=O)Nc1cc(C#N)ccc1C +Cc1ccn2c(=O)c(NC(=O)c3ccccc3Cl)c(C)nc2c1 +CC(C)OC(=O)Cn1nc(C(F)(F)F)c2c1CCCC2 +COc1c(C)cnc(CN(C)C(=O)Cc2cccc3cccnc23)c1C +Cc1cc(C(=O)OC2CC3CCC2C3)ccc1N1CCNC1=O +CN(C)c1ncccc1NC(=O)C1CC1c1ccco1 +CCCOc1cc2c(cc1OC)CCNC2c1cncnc1 +Cc1cncc(C(=O)N=c2[nH]c3ccccc3[nH]2)c1 +O=C(Nc1ccc(F)cc1F)c1cc2ccc3cccnc3c2[nH]1 +CCn1nnnc1COc1cccc(C(=O)NCC(C)C)c1 +COc1cccc(-c2nsc(C(=O)NCC3CC3)c2N)c1 +CC(C)(C)OC(=O)NCc1nnc(SCc2ccccc2)o1 +Cc1ccccc1C(=O)NCCC(=O)OCc1cccc2cccnc12 +CCc1nc(C)c(C(=O)NCC(O)c2ccc(Cl)cc2)s1 +CCC(CCO)NC(=O)Nc1c(C)cc(C)cc1C +CCOC(=O)C1(NC(=O)c2ccnc(SC)c2)CCCC1 +N#Cc1nnn(CCCOc2ccc(Cl)cc2)c1C1CC1 +COc1ccc2cc(C(=O)NCC(C)(C)N3CCOCC3)ccc2c1 +CC(=O)c1ccc(NC(=O)c2ccc(NC(=O)C(C)C)cc2)cc1 +CCN1CC2(CCCN(C(=O)CCCn3cncn3)C2)CCC1=O +c1ccc(Cc2nnc3sc(-c4ccco4)nn23)cc1 +Cc1cccc(C)c1NC(=O)NCCNC(=O)c1ccc(O)cc1 +CCOC(=O)c1cc(-c2cccc(Cl)c2)[nH]n1 +COCCn1nc(C(=O)Nc2nc[nH]n2)ccc1=O +O=c1oc2ccc(CO)cc2n1CCN1CCOCC1 +COCC(O)CN(C)C(=O)c1cccc(NC(=O)C(C)(C)C)c1 +Nc1ccc(Cl)c(C(=O)N2CCNC(=O)C2)n1 +CCOc1ccc(CC(=O)Nc2cccn3nc(C)nc23)cc1 +CCN(CC)C(=O)c1ccc(NC(=O)c2ccc(F)c(F)c2)cc1 +Nc1nc2c(N3CCN(c4ccccc4)CC3)cccn2n1 +O=C(Cc1c(F)cccc1F)NC1CCN(c2ccccc2)C1 +O=C(CSc1ccc2c(c1)CCC2)NCC(O)c1ccc(F)cc1 +CCCCCNC(=O)c1cn(C2CC2)c2cccc(N)c2c1=O +CN(C)S(=O)(=O)c1cccc(NC(=O)c2cccc(Cl)c2)c1 +O=C(Nc1ccc(-c2nc[nH]n2)cc1)c1ccc(N2CCCCC2)cc1 +CCC(C)NC(=O)CCNC(=O)c1cccc(OC)c1 +COc1cc(NC(=O)Nc2cc(C)on2)cc(OC)c1OC +Cc1nc(NC(=O)CCC2CCCO2)sc1C +O=C1CCCN1CCC1CCN(C(=O)c2ccn(C(F)F)n2)CC1 +CCc1ccccc1CNC(=O)c1c(C)nn(C)c1OC +CC(=O)c1cccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)c1 +CC(C)(C)c1cc[nH]c(=NS(C)(=O)=O)c1OC1CC1 +CC(=O)Nc1ccc(NC(=O)c2cc(Cl)ccn2)cc1C +Cc1ccc(-n2ncc(C(=O)N(C)CC(N)=O)c2C)cc1 +Cc1ccc(NS(=O)(=O)c2ccc(N3CCCC3=O)cc2C)nc1 +Cc1nc2cc(NC(=O)CCOC(C)CC(C)C)ccc2n1C +Cc1nn(C)c(C)c1S(=O)(=O)NC(CC(C)C)c1cccs1 +COc1cccc(CC(=O)NCCc2ccccc2OC)c1 +Cc1cccc(C2(CNS(N)(=O)=O)CCCCC2)c1 +COc1ccnc(N2CCN(C(=O)Cc3ccc(C)nc3)CC2)n1 +COCC(C)N(C)C(=O)Nc1cccnc1Oc1ccc(OC)cc1 +COc1ccc2oc(CN3CC4OCCN(C)C4C3)cc2c1 +COC(=O)c1ccnc(NC(=O)CCc2ccccc2)c1 +Cc1ccccc1NC(=O)c1ccc(N(C)C)cc1 +COc1ccc(S(=O)(=O)N2CCOCC2)cc1N +O=C(NCC1=CCCCC1)C(c1cccnc1)N1CCOCC1 +CC(=O)c1cccc(S(=O)(=O)N2CCOC(C)(C)C2)c1 +COc1c(Cl)cc2c(c1OC)C(c1ccco1)NCC2 +O=C(c1ccccc1)C1CCN(C(=O)c2ccc3c(c2)OCO3)CC1 +Cc1c(C(=O)Nc2cccc(-n3cnnn3)c2)sc2ccccc12 +Cn1ccc(CN(Cc2cccnc2)CC2CCCO2)c1 +O=C(NCC1CCCCO1)c1cc2ccccc2[nH]1 +CN(C)C(=O)c1ccccc1NCc1c(Cl)cccc1Cl +COCc1cc(C)nc2sc(-c3nc(N)nc(N(C)C)n3)c(N)c12 +COCCOc1ncccc1NC(=O)N1CCCC1 +COc1cc(NC(=O)NCc2ccccc2)ccc1N1CCCC1=O +Cc1c(Br)cccc1CSc1nncn1C1CC1 +O=C(NCc1ccc2[nH]c(=O)[nH]c2c1)c1c(F)cccc1Cl +COCC1CCCCN1C(=O)c1cn(CCc2ccccc2)nn1 +COc1ccccc1CC(=O)N(C)c1cccc2ncccc12 +FC1CN(C2CCC2)CC1OCc1nc2ncccc2[nH]1 +Cn1nc(-c2ccccc2Cl)cc1C(=O)N=c1[nH]cc[nH]1 +CC(C)COc1cccc(C(=O)NCc2nnc3ccccn23)c1 +Cc1nnc(CCc2ccc(Cl)c(N)c2)nc1C +CCn1ccnc1CNC(=O)CC(c1ccccc1)c1ccccc1C +Cc1cccc(C)c1OCCN1C(=O)CCS1(=O)=O +CCC(C)(C)Oc1cc2c(cc1N)OCC(=O)N2 +CCc1cccc2c(C#N)cn(CC(=O)NCc3ccccc3)c12 +COCCOc1ncccc1C(=O)NCc1ccc(F)c(C)c1 +O=C(Nc1cc(F)ccc1Cl)c1ccnc(F)c1 +O=C(Nc1nc2c(s1)CCCC2)c1ccc(-n2cnnn2)cc1 +CCNC(=O)c1ccc(C)c(NS(=O)(=O)c2ccc(OC)cc2)c1 +CC(=O)Nc1cc(NC(=O)NCCc2ccncc2C)ccc1Cl +CC(C)n1c2ccccc2c2c1cc(C(=O)NCc1ccccn1)n2C +COC(C)C(=O)NCCNc1ncc(C(F)(F)F)cc1Cl +Cc1cn(-c2ccccc2Cl)nc1NC(=O)C(C)n1cncn1 +O=C(CC1C(=O)NCCN1Cc1ccc(Cl)c(F)c1)NCCO +Cc1ccc(CNS(=O)(=O)Cc2ccccc2)cc1 +Cc1cc(C)nc(Sc2ccc(NC(=O)c3ccc(C)o3)cc2)n1 +COc1ccc2cc3cc(C(=O)NCCCOC(C)C)oc3nc2c1 +Cc1cc(NC(=O)C(C)c2cccs2)ccc1C(=O)NC(C)C +COc1ccc(C(=O)Nc2cc(-c3cccnc3)no2)cc1F +Cc1ccc(C)c(C2CSc3nnc(C)n3N2)c1 +CC(C)n1ncc2c(C(=O)OCC(F)(F)F)cc(C3CC3)nc21 +CC(C)C(=O)N1CCCC1C(=O)Oc1ccc(OCC2CC2)cc1 +COC(=O)C(c1ccccc1)N1CCC(C(N)=O)CC1 +COc1ccccc1C(=O)Nc1ccc(OCC(=O)NC(C)C)cc1 +CC(C)c1ocnc1C(=O)Nc1nnc(-c2ccccc2)s1 +O=C(NC1CCCC(C2CC2)C1)N1CCC2(CCOC2)C1 +COc1cccc(COC(=O)C2CC(=O)N(CC(F)(F)F)C2)c1 +O=C(CCC1CCCC1)N1CCN(C(=O)Cc2ccc[nH]2)CC1 +CCOc1ccc(CN(C)CCc2nc3ccccc3c(=O)[nH]2)cc1 +CSc1ccc(C(=O)Nc2c[nH]cc(Br)c2=O)o1 +CN(C(=O)CS(=O)(=O)c1nnc2ccccn12)C1CCCCC1 +CC(C)(C)Oc1nccc(Br)c1OC1CC1 +Cc1cc(C)c2c(NC(=O)CN3CCOCC3)csc2n1 +CCC(=O)c1ccc(S(=O)(=O)N2C(C)CCCC2C)cc1 +N#Cc1cccc(C(=O)N2CCC3(CC2)OCCO3)c1 +COC(=O)CNC(=O)C(NC(=O)c1cccc(C)c1)C(C)C +O=C(Cn1c(-c2cscn2)nc2ccccc21)NC1CCCCC1 +O=C(CC1Sc2ccccc2NC1=O)NCCOc1ccccc1 +Cc1cccc(-n2c(C)cc3c(cnc4ncnn43)c2=O)c1 +N#Cc1cccc(NC(=O)Cn2cnc(C#N)n2)c1 +O=C(NCC1CCN(C(=O)c2ccoc2)CC1)c1cccnc1 +O=C1CCCN1c1cc(F)ccc1Br +N#CCCN(CCC#N)C(=O)CSc1cccc(Cl)c1 +CC1(C)CCC(NC(=O)NCC(=O)NCc2ccccc2)CC1 +CC1CCCC(CNC(=O)CCC(=O)N2CCc3sccc3C2)C1 +CCN1CC2=C(C1=O)C(c1ccccc1Cl)NC(=O)N2 +O=C(Nc1ccccc1)Nc1cc(C(F)(F)F)ccc1-n1cncn1 +O=C(CN1CCN(c2ccccc2)C1=O)NC1CC1 +CCOc1ccc(NC(=O)CCc2ccc3nc[nH]c3c2)cc1 +O=C(C1CCOCC1)N1CCC(O)(c2ccccc2)C2CCCCC21 +Cc1cc(C(=O)Nc2cccc(N3CCCC3=O)c2)c(C)s1 +CC(C)c1n[nH]c(C2CN(Cc3nnc(C4CCC4)o3)CCO2)n1 +Cc1ccnc(-n2nc(C)c(Br)c2C)c1 +CCn1cc(CN(C)S(=O)(=O)c2cn(C(F)F)nc2C)c(C)n1 +O=C(Nc1nccs1)c1cccc(-n2cc(Br)cn2)c1 +CCOC(=O)c1nnc2c(-c3cccs3)c(CC)nn2c1N +CCc1sc(-c2nnc(CSc3nnnn3C3CC3)o2)cc1C +CC(C(=O)N1CCc2cccc(F)c21)n1nnc(-c2ccccc2)n1 +CCN(CC)C(=O)c1cn2ccnc(-c3ccccc3)c2n1 +COc1c(C)cnc(CNS(=O)(=O)Cc2cccc(F)c2)c1C +O=C(NCCn1cnc(-c2ccccc2)cc1=O)c1cccs1 +CC(C)CCC(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 +Cc1cc(C)c(NC(=O)c2cc(=O)c3ccccc3o2)c(C)c1 +COc1ccc(C)cc1NC(=O)c1cc(C(N)=O)cn1C +CN(Cc1ccc(Cl)cc1)S(=O)(=O)c1cn[nH]c1 +COC(=O)c1cc(-c2ccc(OC)cc2)nn1-c1ccccc1 +Cc1nn(-c2ccccc2)c(C)c1NC(=O)Cc1cccs1 +Cc1n[nH]c(NCc2ccc(-c3ccc(F)c(Cl)c3)o2)n1 +COc1ncccc1C(=O)N1CCCN(S(C)(=O)=O)CC1 +CCc1ccccc1NC(=O)C(C)n1cc(Br)cn1 +COC(=O)CN(C(=O)C(C)Oc1ccccc1C#N)C(C)C +Cc1cccnc1NC(=O)Cn1cnc(-c2ccccc2)cc1=O +O=C(C1CCN(c2ncccn2)CC1)N1CCCn2ncnc21 +CCOCCn1c(C(C)=O)nc2cc(Cl)ccc21 +CCNC(=O)c1cnn(-c2ccc(-c3nc(C(C)C)no3)cn2)c1C +O=C(CCN1CCCC1=O)N=c1[nH]c2ccccc2n1C1CCCC1 +COc1cc(C(F)(F)F)cc(C(F)(F)F)c1N +Cc1nc(C)c(CC(=O)Nc2nc3c(s2)CCCC3)s1 +O=C(NCC#CCOc1cccc(C(F)(F)F)c1)c1ccncc1 +CCC(CC)N(C)C(=O)C1(C)Cc2ccccc2C(=O)O1 +COc1ncccc1C(=O)N1CCOC2CCC1C2OC +CCC(O)c1ccc(-c2ccccc2CN2CCOCC2)cc1 +Cc1cnc(CCNC(=O)CCC(=O)c2ccc3c(c2)CCC3)s1 +CC(C)c1n[nH]c(NC(=O)C2COc3ccc(F)cc3C2)n1 +Cc1nn(CC(=O)NCc2ccncc2)c(C)c1Cl +COc1c(Cl)cc(-c2nc3ncccc3o2)cc1NC(C)=O +COCc1cc(C(=O)OC)nc(N2CCOCC2)n1 +Cc1ncc(CNC(=O)c2c[nH]c3ccccc3c2=O)s1 +Cc1nc(CN2CCN(C(=O)c3ccc4[nH]cnc4c3)CC2)cs1 +CCC(C)n1ncc(C(=O)N(C)CCc2ccccc2)c1C1CC1 +CC(=O)c1ccc(NC(=O)c2ccc(N3CCCCCC3)nc2)cc1 +NC(=O)C1CN(CCC(=O)NC2CCCc3ccccc32)CCO1 +O=C(Nc1nc[nH]n1)c1cccc(OC(F)F)c1 +CCc1c(C#N)c(N)nc2sc(C(=O)c3ccccc3)c(N)c12 +CC(NCc1nnc2n1CCCC2)C(=O)N1CCCc2ccccc21 +COCC1CN(Cc2ccco2)Cc2cnn(C)c21 +O=C(CNc1ccc(Cl)c(Cl)c1)N1CCCC1 +CCc1ccccc1NC(=O)Nc1cc2[nH]c(=O)[nH]c2cc1C +C#CCN1C(=O)C(Cc2cccc(OC)c2)Oc2cc(O)ccc21 +O=C(c1cc(OCc2ccccc2)ccc1O)N1CC(O)C1 +CC1CC1C(=O)Nc1ccc(C(=O)NC(C)(C)C)cc1 +O=C(CN1CCCCCC1=O)Nc1cccc(CO)c1 +O=C(Cn1ccn2nc(-c3ccccc3)cc2c1=O)NCc1ccco1 +Cc1cc(C)nc(N2CCCC(C(=O)NC(C)(C)CO)C2)n1 +CCCCN(C)C(=O)NCc1ccc(C(=O)N2CCNC(=O)C2)cc1 +O=C(NCc1ccco1)c1ccc(Br)cc1 +COc1ccc(-c2nsc(NC(=O)c3occc3C)n2)cc1 +O=C(NCCN1CCOCC1)c1ccc(Oc2ncccn2)cc1 +CC(Sc1nc(-c2ccccc2)c[nH]1)C(=O)NCc1cccs1 +O=C(c1ccncc1)N1CCN(c2ncccc2Cl)CC1 +CCC(=O)N1CCCN(C(=O)Nc2ccc(F)cc2Cl)CC1 +CC(C)OC(=O)CCCC(=O)c1ccc2c(c1)CCC2 +C=CCNC(=O)NC1CCN(C(=O)c2ccccc2F)CC1 +COc1ccc(F)cc1C(O)CNc1ccc(C(C)=O)cc1 +CN(Cc1cccc(C#N)c1)C(=O)c1cn(C)nc1C(C)(C)C +O=c1[nH]c2ccccc2n1CCCSc1cccc2cccnc12 +CC1C(c2ccccc2)CCN1Cc1c[nH]nc1-c1cccnc1 +O=C(NCc1cccc(O)c1)c1cccc(Cl)c1 +Cc1cc(C(=O)Nc2cccc(Oc3ccc(C#N)cn3)c2)c(C)s1 +OC1=Nc2nc(N3CCCCC3)sc2C(c2ccccc2)C1 +Cc1noc(C)c1CCCNC(=O)N1CCc2c(F)ccc(F)c2C1 +Cc1nc(CNc2ccc(C)c(-n3nnnc3C)c2)no1 +Cc1cc(CNC(=O)CC2NC(=O)c3ccccc32)n(C)n1 +COCCOc1ncccc1C(=O)N(C)CCO +CC1CCc2c(sc3ncn(CCC(N)=O)c(=O)c23)C1 +CC1Nc2ccccc2N(CC(=O)N(C)CCC#N)C1=O +O=C(NC(c1nccs1)C1CC1)N1CCN(Cc2ccon2)CC1 +CNC(=O)Cc1ccccc1NC(=O)Cc1ccccc1C +CC(=O)Nc1c(C)cccc1C(=O)OCc1ccccn1 +COc1cc(CO)cc2c1OCC(=O)N2CCO +Cn1cnc(CNC(=O)NCCc2ccc(-n3cccn3)cc2)n1 +CCc1nc(C)c(C(=O)N(C)Cc2nc(-c3ccccc3)no2)s1 +O=C(NCc1ccccc1)C1CCCN(c2cnccn2)C1 +Brc1ccc(-n2nnnc2C=CN2CCCC2)cc1 +O=C(Nc1ccc(Cl)cn1)c1nccnc1CO +CCOc1ccc(C(=O)NCC2CCCO2)cc1Br +O=C(Cn1c(-c2nnco2)cc2ccccc21)N1CCOCC1 +Cc1cccc(-n2ncc(C(=O)N(C)C3CC3)c2C)c1 +N#Cc1ccc(CSc2nncn2-c2ccccc2)cc1 +Cn1c(=O)n(C)c2cc(N3CCN(c4ccccc4)CC3)c(N)cc21 +Cc1noc(C)c1S(=O)(=O)N(CCC#N)C(C)C +CNC(=O)C(C)NC(=O)c1ccc(N(C)C)c(F)c1 +Clc1cccc(-c2noc(-c3cc(-c4ccco4)n[nH]3)n2)c1 +Cc1nc2nc(N)nn2c(C)c1CCC(=O)NCc1ccccn1 +COc1ccc2c(c1)OCC(C(=O)NCC(C)(O)c1ccsc1)C2 +Cc1nc(CN(C)C(=O)NCc2cscn2)cs1 +Cc1n[nH]c(SCC(=O)NC(c2cccs2)C(C)(C)C)n1 +Cc1csc(NC(=O)CCc2c(C)[nH]c(=O)[nH]c2=O)n1 +COc1ccc(CCCNC(=O)Nc2cnn(C)c2)cc1 +Cc1cccnc1CC(C)NC(=O)c1ccn2nnnc2c1 +O=C(NCc1nc(-c2ccccn2)no1)c1cc2cc(F)ccc2o1 +CCN(CC1CCCO1)C(=O)c1ccc(C)c(Br)c1 +CC(=O)Nc1ccc(SCC(=O)N2C(C)CCCC2C)cc1 +CCSc1ccc(CC(=O)Nc2nnc(-c3ccccn3)o2)cc1 +COc1ccccc1NC(=O)c1cc(OC)c(OC)cc1C +COc1ccc(CNC(=O)c2ccc(OC)c(F)c2)cc1 +O=C(Nc1cccnc1)C1CCN(c2ccc3nncn3n2)CC1 +COc1ccc(Nc2c(N)c(C)nn2C)c(OC)c1 +N#CC(NC(=O)C1CCCO1)c1ccc(Cl)c(Cl)c1 +Cc1cccc(NC(=O)C2CC(=O)N(C3CCCCC3)C2)c1 +Cc1nc(-c2ccsc2)ccc1C(=O)Nc1ccccc1C(N)=O +CC(C)C(C)(O)CNC(=O)CCN1C(=O)CSc2ccccc21 +FC(F)(F)c1nnc2ccc(Oc3ccccc3)nn12 +CCCCN(CC#Cc1ccccc1)C(=O)c1ccoc1 +Cc1cnc2c(c1)ncn2CCCOc1cccc(N)c1 +CCCN1CCN(C(=O)C2CCCN(S(C)(=O)=O)C2)CC1 +CC(C)(C)CC(=O)NCc1coc(-c2cccs2)n1 +O=C(CCNC1=NS(=O)(=O)c2ccccc21)NCc1ccccn1 +CCc1cc(N2CCN(S(=O)(=O)N(C)C)CC2)n2ncnc2n1 +N#Cc1ccc(COC(=O)CCc2nc3ccccc3s2)cc1 +COc1ccc(-c2nc3c(c(=O)[nH]2)CCCC3)cc1 +Cc1ccc(NC(C)c2cccc(-n3cnnn3)c2)cc1F +CC(C)c1nnc(C2CCN(C(=O)c3ccc[nH]c3=O)CC2)o1 +CC(C)Cc1noc(CNc2ccc(Cl)cc2C(N)=O)n1 +Cc1noc(C)c1C(=O)OC1CCCc2ccccc21 +CC1CCCC(C)N1C(=O)CSc1ncccc1C#N +Cc1cc(NC(=O)C(C)c2ccsc2)c2ncccc2c1 +CNC(=O)Cn1c2ccccc2c2cnn(C)c(=O)c21 +CC(OC(=O)c1cccnc1)C(=O)Nc1cccc(C#N)c1 +CN(C)c1ccccc1NC(=O)CCc1ccccn1 +CCn1nnnc1-c1cccc(C(=O)NCc2cccc(Cl)c2)c1 +CCCNC(=O)Nc1cccc(Cn2ccnc2C(C)C)c1 +Cc1ncoc1C(=O)NC1CCCc2nc(-c3cccnc3)ncc21 +Cc1ccccc1NC(=O)COC(=O)c1ccccc1 +CCCCOC(=O)C1=C(C)Nc2nnnn2C1c1ccccc1OC +O=C(NCc1cccc(COC2CCCC2)c1)c1cc2cccnn2c1 +CS(=O)(=O)NCCNC(=O)c1ccc(NC(=O)C2CC2)cc1 +CN(C)C(=O)CCC(O)c1cccc(Br)c1 +O=C(Nc1ccn(-c2ccccc2)n1)c1sccc1C1CC1 +Cc1nc(-n2cnnc2S(C)=O)c2c3c(sc2n1)CCCC3 +COc1ccc(NC(=O)NCCCn2ccc3cccnc32)cc1 +COCc1ccc(C(=O)Nc2c(C)cc(Br)cc2C)cc1 +Cc1cccc(NC(=O)CSc2ncnc(N)n2)c1 +COc1cc(C)ccc1NCc1nc(C2CC2)no1 +Cc1ccc(-n2nc(C(=O)NC3CC3)cc2C)cc1 +O=C(NC1CC1)N1CCC(F)(F)C2(CCN(c3ncccn3)C2)C1 +O=C1CCCc2c1cc(C(=O)NCCCO)c(=O)n2-c1ccccc1 +COc1ccc(C(=O)COC(=O)c2sc(C)nc2C)cc1OC +CCN(CC)C(=O)CSc1nc(C)nc2sc(C)c(C)c12 +COC(=O)c1c(C)[nH]c(C(=O)OCc2nc3ccccc3o2)c1C +Cn1cccc1CN(CCO)Cc1cc(Br)ccc1F +CC(C)NC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1 +COc1ccc(OC)c(S(=O)(=O)NC2CCCC(C)C2)c1 +CN(CC(=O)Nc1c(Cl)cccc1Cl)C(=O)c1cccnc1 +Cc1nn(C)c(C)c1CC(C)C(=O)Nc1ccc2c(c1)COC2 +O=C(CC1C=CCC1)N1CCCC1c1nnc2n1CCCCC2 +CC(C)(C)c1ccc(-c2noc(CCC(=O)N3CCOCC3)n2)cc1 +Cc1c(F)cccc1NCc1nnnn1-c1ccccc1 +CC(C)Oc1ccc(CCNC(=O)C2CC=CC2)cc1 +CC1CN(Cc2csc(NC(=O)c3nccnc3N)n2)CC(C)O1 +COc1ccc(CCC(=O)N2CCCC(C)C2)cc1OC +CN(C)C(=O)COCc1cncc2c1CCN(Cc1cccs1)C2 +CCN(CC)C(=O)CCc1ccc2c(ccn2C)c1 +Nc1c2c(cc3c1SCCS3)SCCS2 +C=CCn1c(C)nnc1SCc1coc(-c2ccccc2)n1 +CCOc1cccc(C(C)NC(=O)N2CCOCC2)c1 +N#CCC(=O)Nc1ccc(Oc2cccc(Br)c2)nc1 +CN(C)C(CNC(=O)C1CCCCC1)c1cccs1 +COc1ncccc1CN(C)C(=O)c1nccc2ccccc12 +NC(=O)c1nn(-c2ccc(F)c(F)c2)c2c1CCC2 +CC(=O)NCc1ccc(S(=O)(=O)Oc2ccc(F)c(F)c2)s1 +Cc1cc(C)cc(NC(=O)CNC(=O)c2c[nH]c3ccccc3c2=O)c1 +CCOc1ccccc1-c1csc(NC(=O)c2ccncc2)n1 +CC(C)(C)C(=O)Nc1ccccc1C(=O)NCc1cccnc1 +CC(C)C(=O)Nc1ccnn1Cc1cccc(Cl)c1 +NS(=O)(=O)CCNC(=O)C1Cc2ccccc2CN1 +COc1cc(CNC(=O)Nc2cccc(CN(C)C(C)=O)c2)ccn1 +Cc1ccc(C)c(OC(=O)C2CC(=O)N(CC(F)(F)F)C2)c1 +O=C(NC1(c2ccc(Cl)cc2)CC1)c1ccon1 +O=C(Cc1ccc(-c2ccccc2)cc1)NCC1(CO)CC1 +COc1ccc(C(=O)c2cccc(OC)n2)c(OC)c1 +NC(=O)CCCNC(=O)Cn1nc2ccccn2c1=O +C=CCn1nnc(CO)c1COc1ccccc1OC +COCCN(CC(F)(F)F)C(=O)c1cc2ccccc2c(=O)[nH]1 +CC(Oc1ccccc1Cl)C(=O)N1CCN(c2ncccn2)CC1 +O=C(Nc1cccc(C#Cc2ccccn2)c1)c1ccc[nH]1 +CC(C)CNC(=O)C(C)N1CCN(c2ncccn2)CC1 +N#Cc1cnn(-c2cccc(Cl)c2)c1-n1cccc1 +CN(C)C(=O)C(O)c1ccc2c(c1)ncn2C1CC1 +CC(C)c1ccc(OCCNC(=O)C2CC(=O)N(C)C2)cc1 +CCCN(CC(=O)NC)c1ncnc2c1nnn2-c1ccccc1 +COc1ccccc1CNC(=O)Nc1cccc(-n2nnnc2C)c1 +COC(=O)CCn1nc(C(F)(F)F)c(Cl)c1C1CC1 +CN(C)c1ccc(C(=O)NC2CCOc3c(Cl)cccc32)cn1 +CCOC(=O)C1CCN(C(=O)c2ccnc(-c3cccs3)c2)CC1 +CN1CCOC(C(=O)N2CCN(CC3CC3)c3ccccc32)C1 +CCc1cc(C(=O)NCc2nc(-c3ccncc3)no2)[nH]n1 +CCCOc1cn(-c2ccc(F)cc2)nc1C(=O)NC1CC1 +CC(=O)c1cnc2nc(SCc3ccccc3Cl)nn2c1C +Cc1cc(C(=O)N(CCC(=O)N2CCOCC2)C2CC2)c(C)o1 +Cc1nc(Cc2noc(C3CCN(C(=O)OC(C)(C)C)C3)n2)no1 +COCCC1(CNC(=O)N2CCOCC2C2CC2)CC1 +COCc1ccc(C2CCCN2C(=O)Nc2ccncc2)o1 +CC(c1cccnc1)N1CCN(C(=O)c2cc(Cl)c[nH]2)CC1 +CNc1ncnc(N2CCC(C(=O)OC)CC2)c1N +O=C(Cc1csc(-c2ncccn2)n1)N1CCCC2CCCCC21 +CN1CCc2nc(NC(=O)c3cnn(C)c3N)sc2C1 +CS(=O)(=O)N1CCCC1C(=O)NCCOc1ccc(F)cc1 +Cc1ccccc1NC(=O)CSc1nc(C)c(C)c(=O)[nH]1 +O=C1NCCCCC1N1CCN(C(=O)COc2ccc(F)cc2)CC1 +CCNS(=O)(=O)c1ccc(NC(=O)c2ccccc2)cc1 +COc1ccc(C(=O)Nc2cccc(N)c2)c(OC)c1 +Cc1cc(C)nc(SCC(=O)c2ccc(F)cc2)n1 +Nn1ccc2nc3ccn(Cc4cccc(F)c4)c(=O)c3cc2c1=O +Clc1ccccc1-c1noc(-c2ccncc2)n1 +CCN(Cc1ccncc1)C(=O)c1ccc(Cl)cc1 +CC(C)(C)c1ccc(S(=O)(=O)n2ccnc2)cc1 +Cc1cscc1C(=O)NCC(C)(C)c1ccncc1 +Nc1ccccc1NC(=O)NCc1ccccc1Cl +C#CCOc1ccc(C2CC(=O)Nc3c2c(C)nn3C)cc1 +Cc1ccc(O)c(C(=O)N2CCC(OCc3ccccc3C)CC2)c1 +CCCN(C)C(=O)Nc1cc(C)nn1Cc1ccccc1 +CC(C)C(=O)NCCNS(=O)(=O)c1ccccc1 +Cc1nn(C)c(C)c1CN(C)C(=O)c1nn(C)cc1Br +COCCNC(=O)CNC(=O)Cc1c(F)cccc1Cl +COCCNS(=O)(=O)c1ccc(Cl)c(Cl)c1 +Cc1cc(=O)oc2cc(OCC(=O)N3CCCC3)c(Cl)cc12 +Cc1ccsc1CNC(=O)c1cnc2n(c1=O)CCS2 +CCOC(=O)CCC(=O)c1c(F)cccc1Cl +CC(NC(=O)c1ccc(NS(C)(=O)=O)cc1)c1ccccc1 +O=S(=O)(Nc1c(F)cccc1F)c1ccccc1F +COC(=O)C(C)NCc1ccc(C(F)(F)F)cc1 +CC(C)c1noc(CCCNC(=O)c2scnc2C2CC2)n1 +Cc1cc(C(=O)Nc2ccc3nc[nH]c(=O)c3c2)no1 +O=C1NC(c2ccc(O)cc2)Nc2sc3c(c21)CCCC3 +CC(C)N(C)C(=O)c1cc(S(=O)(=O)N2CCCC2)cn1C +Cc1oc(-c2cccs2)nc1Cn1c(=O)oc2ccccc21 +CCC(NC(=O)c1nnc(C)o1)c1ccc(C)cc1C +O=C(Cc1cn2ccsc2n1)NC1CCOc2ccccc21 +COCc1nc2cc(NCc3cccc4[nH]ccc34)ccc2o1 +CC(=O)Nc1ccc(NC(=O)NCCc2cn3ccccc3n2)cc1 +CC1(C)CC(=O)c2cccc(Br)c2O1 +Cc1c[nH]c(=O)n1-c1ccc(C(=O)NC(C2CC2)C2CC2)cc1 +Cc1ccc(Cn2c(=O)c3cccnc3n(-c3ccccc3)c2=O)cc1 +CC(C)(C)C(=O)NCCNC(=O)c1ccc(Br)cc1 +Cc1nn(C)c2c(=O)n(C)c(N3CCc4ccccc4C3)nc12 +O=C(c1ccc(S(=O)(=O)NCc2ccco2)o1)N1CCCC1 +COc1ccccc1C(=O)N1CCC(C(O)c2ccccc2)CC1 +N#CC1(C(=O)N=c2[nH]nc3ccccn23)CCCC1 +COc1ccc(CNC(=O)Cc2n[nH]c3cc(Cl)ccc23)cc1 +O=c1c2ccccc2cnn1-c1nc2ccccc2s1 +Cc1cc(C)n(NC(=O)Cc2cc(F)ccc2C)c(=O)c1 +CCC(C(=O)NC(C)(C)C)n1cccc(OC)c1=O +COc1ccccc1CNC(=O)Cn1ncc(N2CCCC2)cc1=O +CN(C)S(=O)(=O)c1cccc(C(=O)N2C3CCC2CC3)c1 +O=C(NCCCn1cnc2ccccc21)NCCc1cccc(F)c1 +COc1cccc(C(=O)N2CCN(S(C)(=O)=O)CC2)c1 +COc1ccc(C(=O)Nc2ccc(Cl)cc2C)nn1 +Cc1cc(C(=O)OCCCn2ccccc2=O)c2cnn(C)c2n1 +O=C(c1cnccn1)N1CC(c2nc(-c3ncccn3)no2)C1 +CC(Nc1ccc(CC(=O)N(C)C)cc1)c1cccc(Cl)c1 +N#Cc1ccc(OS(=O)(=O)c2ccc(F)c(C#N)c2)cc1F +O=C(Nc1cccc(Oc2ccncc2)c1)c1scnc1C1CC1 +CCn1cnc(S(=O)(=O)N(CC(C)C)CC(C)C)c1 +CCCOC(=O)c1ccc(NC(=O)NCc2ccncc2)cc1 +CCOC1CC(NC(=O)NC2CCCn3nc(CC)nc32)C12CCC2 +COCc1c(C(=O)Nc2ccc(OC)cc2OC)oc2ccccc12 +CCN(CC)C(=O)C(C)Oc1ccc(Br)cc1 +O=C(Nc1cc(Br)ccn1)c1ccccc1 +CC(=O)N1CCC(NC(=O)CCn2c(C)csc2=O)CC1 +CCC(=O)N1CCN(Cc2nc(Cc3ccccc3)no2)CC1 +Cc1cc(C(=O)NC(c2c(F)cccc2F)C(F)(F)F)n(C)n1 +O=C1CNCCC1c1ccccc1Br +Cc1ccc(N2CCC3C2CCN3C(=O)c2cccn2C)nn1 +COc1ccc(C(=O)NC2CCCc3ccccc32)cc1 +COc1ccc(Br)cc1CNC(=O)c1ccccn1 +CCOc1ncccc1-c1cccc2cccnc12 +Cc1ncc(C(=O)N2CCC(CN3CCCC3=O)CC2)s1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)NC(C)c1ccccc1 +O=C(NCc1cc(Cl)c2c(c1)OCCCO2)c1cccs1 +O=C1COc2ccc(C(=O)NC3CCc4cc(Cl)ccc43)cc2N1 +Cc1noc(C)c1Cc1nn2c(-c3cnn(C)c3)nnc2s1 +Cc1nc(C)c(CC(=O)NCCNc2cccnc2)s1 +Fc1cc2c(c(F)c1Cl)CCNC2C1CCOCC1 +COc1ccccc1S(=O)(=O)CC(=O)NC(C)C(C)C +CC(C)C(=O)OC(C)C(=O)N1c2ccccc2NC(=O)C1(C)C +Cc1cc(C(=O)N2CCCN(C(=O)c3ccc(Cl)cc3)CC2)on1 +CCC(=O)N1CCCCC1C(=O)OCc1nc2ccccc2[nH]1 +C=CCn1nnnc1SCC(=O)NC1CCCCC1 +COc1cc(O)ccc1C1NCCc2c(F)cccc21 +Cc1nn(-c2ccc(F)cc2)c2sc(C(=O)NCC(C)C#N)cc12 +CN(C(=O)COCCOc1ccccc1)c1ccc(F)c(F)c1 +CC(c1cccnc1)N1CCN(CC2=Cc3ccccc3OC2)CC1 +COc1ccc(-c2noc(=O)n2CCN2CCOC2=O)cc1OC +CC(CO)NC(=O)c1ccccc1OCc1ccc(F)cc1 +CC1CCC(C(N)=O)CN1C(=O)c1ccc(Br)cc1F +COc1ccc(CCNc2ncnc3c2cnn3-c2ccccc2)cc1 +CS(=O)(=O)N1CCOC2(CCCN(c3cnccn3)C2)C1 +CNC(=O)Cc1ccc(NC(=O)NCC(C)(C)c2ccncc2)cc1 +CC1CC(C)n2nccc2N1C(=O)CCCc1ccccn1 +Cn1c(SCc2ccccc2)nnc1-c1cnccn1 +CN(C)c1ccc(C(=O)Nc2cnn(C(C)(C)C)c2)cc1 +CC(C(=O)N(Cc1ccco1)C1CC1)n1cnc2ccccc21 +N#CCCN(CCC(F)(F)F)C(=O)Nc1cc(Cl)ccc1F +O=C(CCn1ncc2ccccc21)N1CCCCC1 +CCCc1noc(CCCC(=O)Nc2ccc3c(c2)OCCCO3)n1 +C=CCSc1nnc(NC(=O)C2CC2C)s1 +COC(=O)C1CCN(C(=O)c2cc(Cl)c3c(c2)OCCO3)CC1 +O=C1CN(C(=O)CN2CC(c3ccc(Cl)cc3)CC2=O)CCN1 +CC(=O)c1cccc(NC(=O)CSc2nnc(N)n2C2CC2)c1 +COCCN(CCOC)C(=O)c1cnc2ccc(C)cn12 +CC(=O)c1cc(-c2cc(C)[nH]c2C)n(C(C)C)c1C +CC(=O)Nc1cccc(C(=O)OCc2cc(-c3ccco3)on2)c1 +Cc1cc(S(C)(=O)=O)ccc1NC(=O)c1ccsc1 +Cc1cc2occ(CC(=O)N3CCCC3C(N)=O)c2cc1C(C)C +CCC(C)NC(=O)CCC(=O)c1ccc2c(c1)CCCC2 +Cc1cc(C)c(NC(=O)CCC(N)=O)c(Cl)c1 +COCc1ncc(C(=O)Nc2cc(C)ccn2)c(N)n1 +COCCNC(=O)c1sc2cc(C)ccc2c1Cl +Cc1ccccc1CC(=O)Nc1cccc(NC(=O)c2ccncc2)c1 +COc1cc(NC(=O)C(c2ccccc2)n2cnnn2)cc(OC)c1 +CCOc1ccc2nc(C(=O)NCc3ccccc3F)cn2n1 +CCc1nccn1CCN1CCN(CC(N)=O)CC1 +COc1cc(Cn2nnc(-c3cccs3)n2)ccc1SC +COc1ccc(CNc2ccc(C(F)(F)F)cn2)cc1 +O=C1NCCn2c1cc(=O)n(-c1ccc(Cl)c(Cl)c1)c2=O +O=C(c1cccnc1)N1CCc2ccccc2C1c1ccccc1 +Cc1nc(C)c(C(=O)Oc2cccc(C(N)=O)c2)s1 +Cc1ccc(NC(=O)CCNC(=O)N2CCOC(C)C2)c(Cl)c1 +O=C(CCC1CCCO1)N1CCC(CN2CCCCC2=O)CC1 +CC(=O)Nc1cc2c(cc1Cl)[nH]c(=O)c1ccccc12 +O=C(CCC(=O)c1cccs1)NCc1nc(-c2cccs2)no1 +CCNC(=O)C1CCN(C(=O)c2ccc(Cl)c3cccnc23)CC1 +O=C(C1CC1)N1CCN(C2=NC=NC3=NC=NC32)CC1 +COCCn1ccc2nc(C)c(C(=O)N3CCC(C)CC3)cc2c1=O +CC(=O)Nc1ccc(NC(=O)c2cn(CC(C)C)c3ccccc23)cc1 +Nc1nc(-c2ccccn2)ccc1C(=O)N1CCCCCC1 +Cc1ccc(C(=O)Nc2ccc(C)c(C)c2)c(N)n1 +Cc1cc(C)n(CCC(=O)OCC(=O)c2ccc3c(c2)OCO3)n1 +CC(CC#N)N(C)C(=O)c1cc(F)c(F)c(F)c1 +CCCCc1nnc2sc(-c3ccc(N)cc3Cl)nn12 +Cc1cccc(SC2CCN(C(=O)c3cc(O)n[nH]3)CC2)c1 +CNc1snc(C)c1C(=O)N1CCn2c(nnc2C(C)C)C1 +COc1ccccc1C(=O)NCC(=O)NCC1Cc2ccccc2O1 +COC(=O)c1ccc(OC(C)C)c(NCc2nc(C)cs2)c1 +COC(=O)CC1CCCCN1S(=O)(=O)c1cc(C)sc1C +Cc1ccccc1NC(=O)C1CCCN(S(=O)(=O)N(C)C)C1 +Cc1cc(C)n(-c2c(Nc3ccccc3)c(=O)c2=O)n1 +O=C(CC1COC(=O)C1)NC(CC(F)(F)F)c1ccc(Cl)cc1 +O=C(NCc1noc(-c2cccs2)n1)c1ccccc1 +CC(=O)Nc1cccc(-n2nnnc2SCCC(C)C)c1 +O=c1c2cncn2ccn1Cc1ccc(F)cc1Cl +CCC(C)c1ccc2nc(NC(=O)COC)sc2c1 +COc1ccc(NC(=O)Cc2nc3ccc(Cl)cc3c(=O)[nH]2)cc1 +O=C(Cn1ncc2ccccc21)Nc1c(O)cccc1F +O=C(Cn1c(=O)oc2ccccc21)NCc1ccsc1 +CCn1cc(NCc2ccccc2Cl)ccc1=O +CCc1c(C(=O)Nc2ccc(F)cc2F)nnn1-c1ccccc1 +Nc1nccn2c(C3C=C(CO)C(O)C3O)cnc12 +COc1ccccc1OC(=O)CN(C)C(=O)c1cccs1 +c1cnc(NCCNc2ccc3nnnn3n2)nc1 +CCCNC(=O)c1ccc(Cl)cc1NC(=O)C1CCCO1 +CCOC(=O)C1CCN(S(=O)(=O)c2cn(CC)nc2C)CC1 +COc1ccc(S(=O)(=O)N(Cc2ccco2)Cc2ccco2)cc1 +NC(=O)C1CCN(C(=O)COC(=O)C2CCCC2)CC1 +Cn1ccnc1C(=O)C1CCCN(C(=O)CCn2ccccc2=O)C1 +N#CCCCN1C(=O)C2(CCCCCC2)Nc2cc(F)ccc21 +COc1cccc(CNC(=O)c2nnc(Cc3cccc(F)c3)o2)c1 +O=C(Nc1ccccc1OC(F)(F)F)c1ccncc1F +Cc1ccc(C(C)NC(=O)c2csc(C(N)=O)n2)cc1 +CC(C)(C)n1nccc1C(=O)Nc1ccccc1F +CC1Sc2ccc(C(=O)NCCNS(C)(=O)=O)cc2NC1=O +c1cncc(-c2n[nH]cc2CNCCc2ccsc2)c1 +COCCn1cnnc1Cn1cnc2c(C)cccc2c1=O +O=C(CN1CCc2ccccc21)NC(C1CC1)C1CC1 +CN(Cc1ccccc1)S(=O)(=O)c1cccc(Br)c1 +COC(=O)CCc1cc2c(C)cc(=O)oc2c2c1OCN(C(C)C)C2 +Cc1ccc(C(=O)NCCc2ccc(S(N)(=O)=O)cc2)c(O)c1 +O=C(Cc1noc(Cc2c[nH]c3ccccc23)n1)NC1CCCC1 +CNC(CC(=O)OC)C(=O)c1ccc(C(C)(C)C)cc1 +CC(=O)c1cc(F)cc(CNC(=O)OC(C)(C)C)c1 +CN(Cc1ccco1)C(=O)Cn1[nH]c(=O)c2ccccc2c1=O +COc1cc(OC)c(OC)c2c1CCNC2c1nc[nH]n1 +Cc1ccc(S(=O)C(C)C(=O)Nc2cc(Cl)ccc2C)nc1 +COc1ccc(OC)c(CCNC(=O)C2(C#N)CCCC2)c1 +COc1ccccc1NC(=O)NCc1sc(-c2ccco2)nc1C +COc1ccc(OCCC(=O)Nc2cnn(C)c2)cc1 +Cc1cccnc1CC(C)Nc1nccc(-c2ccccn2)n1 +CCn1ncc(Br)c1C(=O)N(C)CC1CC1 +NS(=O)(=O)C1CCCN(c2ncnc3c2cnn3CCO)C1 +COCc1ccccc1NCc1nccn1Cc1ccccc1 +CC(NCC1=NS(=O)(=O)c2ccccc2N1)C(C)n1cccn1 +O=C(c1cccc(OCCOc2ccccc2)c1)N1CCOCC1 +COc1ccc(-c2cc(CO)nn2C(C)C)c(C)c1 +COCCn1cc(C(=O)NC2CCc3ccccc32)c2ccccc21 +CC(C)(C)c1nnc(SCc2ccccc2C#N)n1N +CN(C)c1cccc(C(=O)NCCc2csc(N3CCCC3)n2)c1 +CC(=O)Nc1ccc(NC(=O)CCc2ccc(C)o2)cc1 +CCOC(=O)C1=C(C)Nc2nnnn2C1c1cccs1 +Cc1sc(=O)n(CC(=O)N(Cc2ccco2)C2CCCC2)c1C +O=C(Nc1cccc(-n2cnnn2)c1)c1cc[nH]n1 +CC(C)(C)c1csc(SCC(=O)Nc2nccs2)n1 +CC1CCCCC1NC(=O)c1cccc(CC#N)c1 +COc1ccc(C(C)NC(=O)NCc2cnc(C)s2)cc1F +Cc1cccc(C(=O)N2CC(=O)N(c3ccccc3Cl)CC2C)n1 +COc1ccccc1C(C)NC(=O)c1ccccc1F +CCOCC1CCCN(C(=O)CCc2ccc(F)c(F)c2)C1 +O=C(Nc1ccccc1Cl)c1cccc(-n2cnnn2)c1 +Cc1ccc(CC(=O)NC(C)c2ccc(-n3cncn3)cc2)cc1C +CC(C)C(C)N(C(=O)NCCNC(=O)c1ccccc1)C1CC1 +CC(=O)Oc1ccccc1C(=O)NCCc1ccc(F)cc1 +O=C1COc2cc(C(=O)NCCCn3cccn3)ccc2N1 +CCCNC(=O)CN1CCN(Cc2ccccc2F)C1=O +CCn1cc2c(n1)CN(Cc1cccs1)CC2COCC1CC1 +O=C(Nc1cccnc1)c1ccc(Cn2cccn2)o1 +CCC(C)(C)NS(=O)(=O)c1ccc(S(C)(=O)=O)cc1 +C#CCN1CCN(S(=O)(=O)c2ccc(N(C)C(C)=O)cc2)CC1 +O=C(CC1C=CCC1)NCc1ccc(CN2CCOCC2)cc1 +Clc1ccc(C2CC(c3cccnc3)=Nc3ncnn32)cc1 +CCc1nc(CC(=O)NCC(C)(C)c2ccncc2)cs1 +COC(=O)CSc1nc(Cc2ccccc2)c(C)[nH]1 +COc1ccc(S(=O)(=O)NCc2ccco2)cc1Br +Cc1csc(C(C)CNC(=O)NCCc2ccco2)n1 +CCCn1c(C)cc(C(=O)COc2ccc(NC(C)=O)cc2)c1C +Oc1ccc(C2=CCN(c3ncnc4ccccc34)CC2)cc1 +Cc1nc(CNC(=O)N(C)Cc2csc(C)n2)cs1 +NS(=O)(=O)c1ccc(CNc2cc(C3CC3)ncn2)cc1 +Cn1cc(C(=O)N2CCCCC2c2nc3ccccc3s2)cn1 +Cc1nc(CN(C)C(=O)c2sc(-c3ncccn3)nc2C)cs1 +COc1ccccc1C(C)Nc1ccc2nnc(C(F)(F)F)n2n1 +Cc1ccc(C(=O)N2Cc3ccccc3C(c3ccccc3)C2)c(=O)[nH]1 +Cc1ccccc1NC(=O)c1cc(S(N)(=O)=O)ccc1F +CNc1ncccc1C(=O)N1CCC(C)(O)C(O)C1 +COc1ccc(Cl)cc1CNC(=O)CC(C)C +CCOC1CCC2C1OCCN2Cc1ccc2ccccc2n1 +CC(C)(C)C(=O)N1CCC(Oc2cnccn2)CC1 +Cc1ccc(C(N)=O)c(OCc2noc(C3CC3)n2)c1 +COc1ccccc1-c1nnc(SCC(=O)NC(C)C(C)C)n1C +COCCC(=O)NC1CCC2(CC1)CNC(=O)c1cc(C)ccc1O2 +CCCCCNC(=O)C(C)Oc1cccc(C)c1N +Cn1cc(C(=O)NCc2ccccc2Cn2cccn2)c2ccccc21 +CC(NC(=O)C1(c2ccc(Br)cc2)CC1)C(N)=O +Nc1ccccc1OCCCn1nnc2cc3c(cc21)OCCO3 +C#CCN1CCN(C(=O)c2n[nH]c3ccccc23)CC1 +CC(C(=O)NC1CC1)N1CCN(C(=O)C2CC(=O)N(C)C2)CC1 +Cc1cn(C)nc1C(=O)Nc1sc2c(c1C#N)CCC2 +CC(O)CNC(=O)c1nc(-c2cccc3[nH]ccc23)no1 +O=C(CCN1CCN(C(=O)C2CCCO2)CC1)Nc1ccccc1 +COc1ccc(OC)c(CN(C)C(=O)CCC2CCCC2)c1 +CCn1c(C(C)NC(=O)c2nccc3ccccc23)nc2ccccc21 +O=C(COC(=O)c1cccc(O)c1)NCCc1ccccc1 +CN(C)C(=O)COc1cccc(NC(=O)c2ccccc2)c1 +CCN(CCC#N)C(=O)CSc1ncn(-c2ccccc2)n1 +O=C1CN(C(=O)c2cc(F)ccc2-n2cccc2)CCN1 +Cc1ccc(CC(=O)Nc2nc(-c3ccncc3)cs2)cc1 +COc1ccc(Cl)cc1C(N)C(=O)NC1CC1 +CCCCN1C(=O)C(O)(CC(=O)c2ccco2)c2ccccc21 +CC(C)N1CCC(NC(=O)NCc2cc(=O)[nH]c3ccccc23)C1=O +O=c1c2c(c1=O)Cc1cc3c(cc1C2)COS(=O)C3 +CC(C)(C)Oc1ccc(C(=O)Nc2cccnc2)cc1 +CCCC(C#N)NC(=O)c1nc(S(C)(=O)=O)n2ccccc12 +CCCn1nc(C(=O)NCc2ccc(O)c(OC)c2)ccc1=O +Cc1cc(C)n2nc(C(=O)N3CCN(c4ccccc4)CC3)nc2n1 +Nc1cc(C(=O)CCC(=O)N2CCOCC2)ccc1Cl +Cc1nn(C)c(=O)c(C(=O)NCCc2ccc(OC(C)C)cc2)c1C +CCCC1CN(C(=O)C2CC(=O)N(c3ccccc3OC)C2)CCO1 +Cc1cnc(SCCC(C#N)NC(C)C)nc1 +CCCCN(C)c1ncnc(N(C)Cc2ccccc2)c1N +CCN1CCN(S(=O)(=O)c2ccc(C(C)C)cc2)CC1 +CC(C)CC1(CNC(=O)NCC2(CO)CC2)CCCC1 +O=C1CC(NC(=O)C2(c3ccccc3)CCOCC2)CN1C1CC1 +Cc1cc(NC(=O)CCCN(C)S(=O)(=O)c2cccs2)no1 +CC(=O)c1cccc(OCc2cc(C(=O)N3C(C)CCC3C)no2)c1 +NS(=O)(=O)CCNC(=O)CCc1cccc(Br)c1 +O=C(NCc1nnc2n1CCC2)c1cccnc1Oc1ccccc1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3ccc(CC#N)cc3)cc2)n1 +COc1ccc(F)cc1C(=O)NCCNC(=O)c1ccccc1O +Cc1ccc(CC(=O)N2CCN(C(C)c3ccsc3)CC2)cn1 +Cc1c(CCC(=O)Nc2ccc(F)cc2C#N)cnn1C +Cc1ccccc1Cn1ccnc1CN(CC1CC1)C(=O)C(C)C +Cc1ccc2c(CC(=O)N(CCC#N)Cc3cccnc3)coc2c1C +Cc1nn(C)cc1-c1cc(C(F)(F)F)nc(N2CCOCC2)n1 +CC(C)(O)CCc1cccc(C(=O)N2CCC2c2ccccc2)c1 +CCSc1ncc(CN2CCCC(c3cc(=O)[nH]cn3)C2)cn1 +Cc1ccc(NC(=O)Nc2ccc(Cn3cncn3)cc2)cc1C +Cc1cc(C(C)NS(=O)(=O)c2ccc(C#N)cc2)c(C)s1 +N#CCn1c(C(F)(F)F)nc2c(cnn2-c2ccccc2)c1=O +Cc1ccc(NCC(=O)N2CCCC(C(N)=O)C2)cc1C(=O)N(C)C +CC(Nc1ccc(=O)n(C)c1)c1ccc(Cl)cc1 +Cc1cccc(OC(C)C(=O)NCc2ccc(S(N)(=O)=O)cc2)c1 +O=C(CC1(O)CCCC1)NC(c1cccnc1)c1ccc(F)c(F)c1 +N#CCOc1cccc(CC(=O)Nc2ccc(Cl)cc2)c1 +Brc1ccccc1-n1cc(NC2CCOCC2)cn1 +CCN(CC)c1ncnc(Oc2cccc3cccnc23)c1N +O=C1CN(C(=O)Cc2ccc(N3CCCC3=O)cc2)c2ccccc2N1 +CC(NCC(c1cccs1)N1CCOCC1)c1ccc(C#N)cc1 +N#Cc1ccccc1CNCc1ccc(F)cc1F +COC(=O)N(C)c1ccc(NC(=O)C(C)(C)C)cc1 +O=C(Nc1ccccc1C(=O)NCCc1ccccn1)c1ccccc1 +O=C(NCc1ncccc1F)c1ccc(-n2ccnn2)cc1 +O=C(CN(Cc1cccnc1)CC1CCCO1)Nc1cccnc1 +COc1cccc(OC)c1C(=O)NCCc1ccsc1 +CC1CCN(S(=O)(=O)n2nnc3ccccc32)CC1 +CS(=O)(=O)N1CCN(C(=O)c2coc(NC(=O)C3CC3)n2)CC1 +COc1cccc2c1cc(C(=O)NCC(C)O)n2C +Cc1cc(NC(=O)c2cc(-c3ccco3)nc3onc(C)c23)no1 +Cc1nnc(SCC(N)=O)c2c1cnn2-c1ccccc1 +CC(C)n1cc(NC(=O)NCCCn2ncc3ccccc32)cn1 +CN(CC12CCCC1N(C)C(=O)CC2)C(=O)NC1CCCCC1 +COc1ccc(NC(=O)C2CCCO2)cc1OC +Cc1cc(CN(C)C(=O)c2sc(-c3ccccn3)nc2C)no1 +Cn1c(SCc2c(F)cccc2F)nnc1-c1cnccn1 +COC(=O)c1[nH]c(C)c(C(=O)CN(C)C(=O)C(C)C)c1C +N#Cc1cc(NC(=O)Cc2cccc(Cl)c2)ccc1F +CCCn1cc(C(=O)N(C)C(C)c2ccncn2)c(C)n1 +Cc1ccc(NC(=O)CC(NC(N)=O)c2ccccc2Cl)c(O)c1 +CCCn1c(N)c(-c2csc(-c3ccco3)n2)c(=O)n(C)c1=O +CCc1ccc(Oc2ccc(CCNC(=O)CC#N)cc2)cc1 +COc1ccc(CNc2nc(-c3ccco3)n[nH]2)cc1OC +CCCCCNC(=O)N1CCN(c2cnccn2)CC1 +CN(CC(=O)Nc1ccc(Cl)cc1)Cc1nc(N)nc(N(C)C)n1 +CC(=O)c1cccc(NC(=O)N2CCCC(C(=O)NC3CC3)C2)c1 +CC1CC(=O)NCCN1c1ncnc2sccc12 +COc1ccc(-c2cc(C(C)=O)c(C3CC3)o2)cc1OC +CCN(C1CCCC1)S(=O)(=O)c1cc(Br)cnc1N +CC(NC(=O)NC1CCCC1C(N)=O)c1cccc(N2CCCC2)c1 +CNC(=O)NCC(=O)N(C)CCc1cccs1 +COc1ccc(CNC(=O)N(Cc2ccco2)C2CCOCC2)cc1 +Cc1ccc2ncc(C(=O)Nc3nc4ccccc4s3)c(=O)n2c1 +O=C(Cn1nc(-c2ccco2)oc1=O)N1CCC2(CC1)OCCO2 +Cc1ccc(N)cc1NS(=O)(=O)c1ccccc1Cl +CC(=O)c1ccc(NC(=O)NCCCc2nc(C(C)C)no2)cc1C +COC(=O)CCn1cnc2sc3c(c2c1=O)CCC(C)C3 +COc1ccc(SCC(=O)N2CCCC(C(F)(F)F)C2)cc1 +Cc1ccc(NC(=O)Cc2csc(N3CCNC3=O)n2)c(O)c1 +C#Cc1cccc(NC(=O)C2COc3ccccc3O2)c1 +O=C(C1CCc2ccccc2C1)N1CCN(CCn2cncn2)CC1 +CNS(=O)(=O)c1cc(C(=O)N2CCCCC2)cc(C)c1C +CCn1nc(C)c2c(C(=O)NCC(=O)C(C)(C)C)cc(C)nc21 +Cc1nc(CCNc2ccccc2Br)sc1C +CCC1Nc2cc(F)ccc2N(CCC(N)=O)C1=O +CN(Cc1ccco1)S(=O)(=O)c1cccc(Cl)c1 +CC1CCCCN1C(=O)c1cccc(N2CCCS2(=O)=O)c1 +Cc1cc(C(=O)OCCc2cccnc2)ccc1-n1cncn1 +COc1cccc(CN2CCCCS2(=O)=O)c1 +CCN(CC(C)C#N)S(=O)(=O)c1cc(C)ccc1C +O=C(CN1CCCCC1=O)NCC1(c2ccccc2)CCOCC1 +N#Cc1cnc2ccc(N3CCOCC3)cc2c1Cl +CC(C)CCCC(C)NS(=O)(=O)c1cnc(N)nc1 +O=C(Nc1cccc(Cn2cccn2)c1)c1cc2ccccc2o1 +CCCc1nnc(NC(=O)NCCc2cn3ccccc3n2)s1 +CC(Oc1ccc(F)cc1)C(=O)Nc1cccc(C(N)=O)c1 +COc1cc(-c2nc(CN3CCOCC3)c(C)o2)cc2c1OCO2 +COC(=O)c1ccc(S(=O)(=O)Nc2ccn(C)n2)c(C)c1 +COc1ccc(Cn2nnnc2SC(C)C(=O)NC(C)(C)C)cc1 +CCc1nnc(NC(=O)NCc2csc(NC)n2)s1 +CC1CNc2cc(S(=O)(=O)N3CCCCCC3)ccc2O1 +Cc1ccc2ncc(C(=O)Nc3cnc(C4CC4)nc3)n2c1 +N#CC1(NS(=O)(=O)Cc2ccc(F)cc2)CCOCC1 +Cc1ccc(-c2ccc(C#N)c(=O)n2CC(=O)N2CCOCC2)cc1 +CC(=O)Nc1ccc(CCNC(=O)C(C)(C)c2ccccc2F)cc1 +CCC(C)(C)NC(=O)c1ccc(-c2ccco2)[nH]c1=O +Cc1ccc(C)c(C(=O)Nc2nnc(C3CCCO3)o2)c1 +Cc1nnsc1SCCNC(=O)c1c(F)cccc1F +CC(=O)N1CCCC1c1cncc(Cc2cccc(F)c2)n1 +CN(CCc1ccccn1)c1nc2ncccc2o1 +CCN(Cc1cnn(C)c1)C(=O)c1cncc(Br)c1 +NC(=O)c1ccc(C(=O)OCC(=O)N2CCNC(=O)C2)cc1 +CC(C)(CNC(=O)Nc1cccc(S(C)(=O)=O)c1)c1ccncc1 +O=C1NCC(=O)N2CCN(Cc3cccc(OC4CCCC4)c3)CC12 +CC(Cc1cn(Cc2ccoc2)nn1)c1ccccc1 +CN(Cc1nccn1C)C(=O)c1ccc2nc(C3CC3)oc2c1 +C#Cc1cccc(NC(=O)N2CCC(N3CCOC(C)C3)CC2)c1 +O=C(NCc1nc(Cc2ccc(Cl)cc2)no1)OCC(F)(F)F +Cc1cc(C)cc(CCNS(=O)(=O)N2CCOCC2)c1 +Cc1nnnn1-c1cccc(NC(=O)N(C)CCOCC2CC2)c1 +CC(C)C(NC(=O)c1ccco1)C(=O)NCC1CN(C)CCO1 +Cc1ccccc1CNC(=O)CCn1cnc2ccccc2c1=O +O=C(NCc1csc(=O)[nH]1)c1ccc(Cl)cc1O +O=C(CSc1ccc(F)cc1)NC1Cc2ccccc2C1 +CC(=O)N(C)CC(=O)NCc1ccccc1-c1ccc(Cl)cc1 +CCc1onc(C)c1NC(=O)NC(C)Cc1ccc(O)cc1 +CCOC(=O)c1ccc(NCc2cnn(C)c2)nc1 +CCOC(=O)N1CCc2nc(NC(=O)c3ccc(C)cc3)sc2C1 +N#CCc1ccc(NC(=O)CNc2ccccc2C(=O)NC2CC2)cc1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)Cc1c[nH]nc1C(C)(C)C +COc1ccccc1OC1CCN(C(=O)C2CCC(=O)N2)CC1 +CCOC(=O)c1cc(C)nc(N2CCCC2Cn2ccnc2)n1 +N#Cc1cc(NC(=O)Cc2csc(N3CCNC3=O)n2)ccc1F +CC(C)Cn1ncc(C(=O)NC(C(N)=O)C(C)C)c1C(F)F +O=C(NCCCn1cccn1)C1Cc2ccccc2S1 +O=C(CN1CCN(C(=O)c2ccco2)CC1)NCc1ccco1 +Cn1ccnc(NC(=O)c2ccc(Br)cc2Cl)c1=O +Nc1cccnc1Sc1nnc2n1CCCCC2 +CC(Sc1nnc(Cn2cncn2)o1)c1ccccc1 +CC1CN(C(=O)Nc2ccc(F)c(C#N)c2)CC(C)O1 +CCC(NC(=O)c1cnn(C)c1C)C1CCCCC1 +COC1CCN(C(=O)NCc2cnn(C)c2)CC1 +O=C(COc1ccc(Cl)cc1)N1CCN(C(=O)c2ccc[nH]2)CC1 +NC(=O)COc1ccc(NC(=O)c2ccc(=O)[nH]c2)cc1 +Cc1cccc(NS(=O)(=O)c2ccc(C)c(C)c2)n1 +Cc1[nH]n(-c2ccccc2)c(=O)c1C(=O)c1cnc2c(c1)c(C)nn2C +CC(C)N(CCCO)C(=O)COc1ccccc1Cl +CC(=O)Nc1cccc(-n2nnc(CO)c2C(C)(C)C)c1 +CCC(C)n1nccc1NC(=O)c1cccc(C)c1 +CCOC(=O)CCN1CCCN(S(C)(=O)=O)CC1 +CC(=O)Nc1ccc(C(=O)COc2ccc(C)c(C)c2)cc1 +Cc1occc1CN(C)C(=O)c1cc(-c2ccco2)nc2ccccc12 +O=C(OC1CN(c2nc3ccc(F)cc3s2)C1)c1ccc(=O)oc1 +Cc1nnc(C2CC3OCCC3N(Cc3cccs3)C2)o1 +Cc1nc2nc(Cc3ccccc3)nn2c(C)c1Cl +CNS(=O)(=O)c1cc(C(=O)NCC2CC2C)ccc1Cl +COC(=O)c1ccc(C(=O)Nc2nc(-c3ccccc3)ns2)s1 +CCC(C)CNC(=O)C(CC)Sc1ccc(N)cc1 +Cc1csc(CCNC(=O)c2nccc3c(N)cc(F)cc23)n1 +CC(C)c1nc2ccccc2c2nnc(SCC(N)=O)n12 +COc1cc(-c2cc(=O)n3c(n2)CCCCC3)cc(OC)c1OC +Cn1c(C(=O)N(CC(F)(F)F)C2CCC2)cccc1=O +Cc1cccnc1NC(=O)c1ccc(NC(=O)c2ccccc2)cc1 +Cc1cccc(C)c1OCC(O)CN(C)S(=O)(=O)O +COc1ncccc1C(=O)NCC#CCOc1ccc(F)cc1F +Cc1cc(-c2ccccc2)nn(C(C)CN2CCOCC2)c1=O +CC(C)N(C(=O)CCSc1ccccc1F)C1CCOCC1 +CC(Sc1nc(-c2ccccn2)n[nH]1)C(=O)N(C)C +COCCC(=O)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1 +CCn1nc(C)cc1C(=O)N1CCOCC(Oc2cccnc2)C1 +CCCOCC(=O)N1CCN(C(=O)c2ccc(Cl)cc2F)CC1 +CC(=O)Nc1ccc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)cc1 +Cc1cc(NC(=O)c2ccc(Br)cn2)ccc1N +Cc1[nH]c(=O)c(C(=O)NCc2ccncc2)c(C)c1N +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)NCC1(C)CCCC1 +COC(C(=O)N(C)CCc1ccc(F)cc1)c1ccccc1 +COc1cccc(OC)c1COC(=O)c1ccc(=O)n(C)c1 +O=C(CCc1cnn(-c2ccccc2)c1)Nc1ccc2[nH]c(=O)[nH]c2c1 +CC(NC(=O)C12CC3CC(CC(C3)C1)C2)C1CCCO1 +Nc1cc(N)cc(-c2n[nH]c(-c3ccccc3)n2)c1 +CCOC(=O)CN(CC)C(=O)c1ccc(N(C)C)cc1 +CN(C1CCCCC1)S(=O)(=O)NCCc1ccccn1 +Nc1ccc(NC(=O)Nc2ccc(Cl)cc2)cc1F +CC1(C(=O)Nc2cccc(Cl)c2)Sc2ccccc2NC1=O +COCC(C)NC(=O)Nc1ccc(CCC(=O)N2CCCC2)cc1 +CC(CN1CCOCC1)OC(=O)c1cccs1 +Cc1ccc(-c2nccn3cc(C(=O)NC(C)C)nc23)cc1 +C#CCn1c(=NC(=O)c2ccnn2C)sc2cc(F)ccc21 +COC(CNC(=O)c1cccnc1N1CCCCC1)c1ccccc1 +OC(CCNc1nc2ccccc2s1)C(F)(F)F +NC(=O)N1CCCC(C(=O)NCCc2cc(Cl)cc(Cl)c2)C1 +CCc1n[nH]c(SCC(=O)c2ccc3ccccc3c2)n1 +O=C(CCn1cnnn1)NCC1COc2ccccc2C1 +CC(=O)c1cccc(NC(=O)c2cc(-c3ccc(F)cc3)[nH]n2)c1 +COc1cccc(N2CCN(C(=O)c3cc(OC)ccc3O)CC2)c1 +CC(C)OCCS(=O)(=O)c1ccccc1C#N +CCCC(C)C(=O)NCCNc1ncnc2ccccc12 +Cc1ccc(Cl)cc1S(=O)(=O)NCCNC(=O)C1CC1 +CS(=O)(=O)N1CCc2c(C(=O)N3CCCC3)n[nH]c2C1 +CCn1cc(NC(=O)NCCc2ccc(C)c(OC)c2)cn1 +Nc1cc(S(=O)(=O)NCCS(N)(=O)=O)ccc1O +CCOC(=O)c1c(C)c(C(=O)Nc2ccc(F)cc2)c(C)n1CC +COc1ccc(S(=O)(=O)C2CN(C(=O)CC(C)C)C2)cc1 +COc1cccc(CN2CCOC3(CCc4ccccc43)C2)c1OC +Cc1cc(C)cc(NC(=O)CNC(=O)c2ccccc2F)c1 +OCC(c1ccccc1)C1NCCc2ccccc21 +CC(=O)Nc1ccccc1Oc1ccc(F)cc1C(C)=O +CC(C)CCNC(=O)C(N)c1ccc(F)cc1F +Cc1cc(O)ccc1-n1nnc(-c2ccc(F)c(F)c2)c1N +CCCCn1nnc(NCc2cccc3ccccc23)n1 +CC(NCc1ccncc1)=C1N=C(c2ccc(Cl)cc2)OC1=O +CC(C)CCNC(=O)Cn1cnc2c(nc3n2CCCCC3)c1=O +O=C(Cc1scnc1-c1cccs1)NCc1ccco1 +O=C(NCc1nc(Cc2ccccc2)no1)Nc1cccnc1 +COC(=O)c1cnc(N)nc1-c1cccc(Br)c1 +CCC1CCCCN1C(=O)NCCOCC(F)(F)F +CC1=C(C(=O)OCC(C)C)C(c2ccc(O)cc2)NC(=O)N1 +O=C(Cn1nc(C2CC2)n(-c2ccccc2)c1=O)NCc1ccco1 +CC(C(=O)Nc1c(F)cccc1F)n1ncc2ccccc2c1=O +CC(NC(=O)c1ccc(=O)n(C)n1)c1cccc2ccccc12 +Cc1cc(C)n(C2CCN(Cc3cnc(C4CCCCC4)nc3)C2)n1 +Cc1cc(CS(=O)(=O)NC2CCCC(C)C2C)on1 +O=c1[nH]c2ccc(C(O)c3ccccc3Cl)cc2[nH]1 +N#CCn1c(Cc2cccs2)nc2cc3c(cc21)OCO3 +Cc1nc(NC(=O)CC2C=CCC2)sc1-c1nccn1C(F)F +Cc1cc(=O)c(O)c(CN2CC(C)OC(C)C2)n1C1CC1 +CN(C)c1c(Cl)cccc1NC(=O)N1CCOC(C)(C)C1 +CCOC(CC)C(=O)NCCc1c(F)cccc1F +CN1C(=O)CCC2(CNC(=O)c3cc(Cl)ccc3F)CCCC12 +CCc1cc(C(=O)OC(C)COc2ccccc2)n[nH]1 +CCn1cnnc1SCC(=O)Nc1cc(C)cc(C)c1 +COc1ccccc1C1(NC(=O)Cn2nc(C)cc2C)CCCC1 +O=C(Cn1nc2n(c1=O)CCCCC2)OC1CCCCC1 +O=C(NCC1CCCc2ccccc21)N(CCO)C1CC1 +CCCC1=C(C(=O)OC)C(c2sccc2C)NC(=O)N1 +COc1ccccc1C1(CC(N)=O)CCOC(C)(C)C1 +N#Cc1ccc(NC(=O)Cn2cccnc2=O)cc1 +O=c1[nH]nc(CSc2nnc(-c3ccco3)n2C2CCCCC2)[nH]1 +CN(CCc1ccncc1)C(=O)NCc1cc2cc(F)ccc2s1 +CCOc1cc(C(=O)NCc2nc(C)cs2)ccc1OC +Cc1csc(N2CCCN(C(=O)NCc3ccncc3)CC2)n1 +CN1CC(=O)N(c2ccccc2)CC12CCN(C(=O)C1CCCC1)C2 +Cc1nn(CC#N)c(=O)n1-c1cccc(C(F)(F)F)c1 +O=C(Nc1cccs1)N1CCC(Cn2cc(C3CC3)nn2)CC1 +COCCOc1ccccc1NC(=O)c1nc2nccc(C)n2n1 +COC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2cccs2)c1C +Cc1cc(OCC#N)nc(-c2ccc(Cl)cc2)n1 +CCN(CC)C(=O)CCC(=O)N1CCOc2cc(C)ccc21 +CCCC(CC(=O)OC)NC(=O)c1ccc(F)cc1Cl +c1ccc2c(c1)OCCC2NCc1c(C2CC2)nc2sccn12 +COCCOCC(=O)Nc1ccccc1-n1cnnn1 +CC(=O)N1CCN(C(=O)c2cncs2)C(C(=O)N(C)C)C1 +CCN(Cc1cccc(C)c1)C(=O)c1ccccc1COC +O=S(=O)(Cc1cc(F)ccc1F)N1Cc2cncnc2C1 +COC(=O)CC(C)NC(=O)Cc1ccc(Cl)cc1 +OCc1ccc2oc(-c3ccc4c(c3)OCO4)nc2c1 +Cc1ccc(F)c(S(=O)(=O)NCc2cscn2)c1 +O=C(NCC1CC12CCc1ccccc12)c1ccc(-n2cncn2)nc1 +CCOCC1CCCN(S(=O)(=O)c2ccc(NC(C)=O)cc2)C1 +CCCn1ccc2cc(NC(=O)c3cscn3)ccc21 +N#Cc1cccc(S(=O)(=O)Nc2ccc(NC(=O)C3CC3)cc2)c1 +CCc1ccc(CCC(=O)NCc2nnc3ccccn23)cc1 +NC(=O)c1oc2ccccc2c1NC(=O)c1ccc2ncsc2c1 +COC(=O)Cn1c(CCNC(=O)C2CCCO2)nc2ccccc21 +Cc1c(NCCC(C)(C)C)cccc1S(N)(=O)=O +N#Cc1c(NC(=O)c2ccc3c(c2)OCCO3)sc2c1CCC2 +O=C(NCCCc1nnc2ccccn12)c1ccc(-n2cnnn2)cc1 +CC(CNC(=O)NCC(C)(C)c1ccncc1)N1CCOCC1 +CN1CC(NC(=O)c2ccc(Br)cc2F)CCC1=O +Cc1nn(C)c(C)c1C1CCCN1c1cccc(F)c1C#N +COc1ccc(C)cc1NC(=O)COc1ccc2c(c1)OCO2 +CN(Cc1ccccc1F)C(=O)COc1ccc(F)cc1 +CN(Cc1ccsc1)C(=O)C1CC(=O)N(Cc2ccco2)C1 +Cc1cccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)c1 +C#CCN(CC#C)C(=O)c1c(F)ccc(OCC)c1F +CN(Cc1ccccn1)C(=O)NCCCC1CCCC1 +COCCCNC(=O)CCC1NC(=O)c2ccccc2N=C1O +CC(C)N(C)C(=O)NC1CCCN(C(=O)OC(C)(C)C)C1 +CCC1CN(C)c2ccccc2CN1C(=O)c1cnccn1 +NC(=O)C1(CNC(=O)NCCc2cccs2)CCOCC1 +Cc1nc(C)n(Cc2cc(Br)cs2)n1 +CCOC(=O)N1CCN(C(=O)Cn2cnc(C)cc2=O)CC1 +CNC(=O)COC(=O)C(C)Oc1ccc(C(C)C)c(C)c1 +COC(=O)c1ccc(NC(=O)CCn2ncc3ccccc32)cc1 +O=C(Nc1cccc(-n2cncn2)c1)N1CCCC2(CCOCC2)C1 +Cn1cc(NC(=O)COCC(F)(F)F)cc(Br)c1=O +CN(C)C(=O)c1ccc(Oc2ccc(F)cc2F)cc1 +CNC(=O)c1cccc(CNC(=O)c2cc(C)n[nH]2)c1 +Cn1nc2n(c1=O)CCN(C(=O)Nc1ccc(F)c(F)c1)C2 +CC(C)OCCCNC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +CNC(=O)c1ccc(NC(=O)c2nonc2C)cc1 +CN(Cc1ccco1)C(=O)c1cnc2sc3c(n2c1=O)CCCC3 +CCn1nc(C(C)C)cc1C(=O)NCc1sccc1C +COc1ccccc1C(=O)N1CCNCC1c1ccccc1 +O=C(NCCc1ccccc1)N1CCC(Oc2cccnn2)CC1 +Cc1ncnc(N2CCCC3(CCC(=O)N(CCC(C)C)C3)C2)c1C +COC(=O)N(C)CC(=O)NCc1ccc(Cl)cc1Cl +COCCOC1CCN(C(=O)c2c[nH]nc2-c2ccccc2F)CC1 +CN(C)C(CNC(=O)COc1ccc(Cl)cc1)c1cccs1 +O=C(NCc1nnc(C2CC2)n1C1CC1)c1ccc2ccccc2c1 +COc1ccc(NC(=O)c2ccc(CNC(N)=O)cc2)cn1 +Cc1ccc(C(=O)OC(C)C(=O)NC2CCCC2)cn1 +CCC(C)C(NC(=O)c1ccc(-n2ccnn2)cc1)C(N)=O +Cc1cc(C)cc(OC(=O)C(C)S(=O)(=O)c2ccc(F)cc2)c1 +O=c1ccn(Cc2ccc(F)c(Br)c2)c(=O)[nH]1 +CC(OC(=O)CCc1ncc(-c2ccccc2F)o1)C(N)=O +O=C(COc1ccc2c(c1)CCC2)NCc1nc2ccccc2s1 +CC(=O)Nc1ccc2c(c1)-c1cc(NC(C)=O)ccc1C2=O +CC(C(=O)NCCC(=O)N1CCCC1)c1cccs1 +Cc1cc(Br)c2[nH]cc(Br)c(=O)c2c1 +CCc1cccc(CC)c1NC(=O)CCSc1nnnn1C +CCc1noc(CC)c1CNC(=O)c1cc(Cl)c[nH]1 +COc1ccc(CN(C)C(=O)c2cnn(-c3ccccc3)n2)cc1F +Cc1ccc(Oc2ccc(NC(=O)Cn3ccnc3)cc2)cc1 +CCOC(=O)c1ccc(NC(=O)COc2ccccc2C#N)cc1 +Cc1noc2ncc(-c3nnc(-c4cccc5ncccc45)o3)cc12 +CN(CCOCC1CC1)C(=O)C1(c2cccc(Cl)c2)CC1 +CCCNC(=O)CNC(=O)c1ccccc1NC(=O)NC(C)C +Cn1cc(C(=O)Oc2ccc3c(c2)ncn3C)nn1 +O=C(COc1ccccc1Br)NCC(F)(F)F +CC(=O)Nc1ccc(C(=O)NC2CCC(C)CC2)s1 +O=C(NCC1CCC1)Nc1cccc(-c2cnco2)c1 +CCOc1nc(CC(C)C)nc(NCc2ccccn2)c1N +CCC1COCCN1C(=O)c1cc(-c2ccncc2)n[nH]1 +CCCCNC(=O)c1cnn(Cc2ccccc2)c1CC +Cc1ccoc1C(=O)NCCCNC(=O)c1ccc2[nH]ccc2c1 +CC(C)Oc1ccc(C#N)cc1NC1CCN(C(=O)N(C)C)CC1 +COCc1cccc(CNC(=O)c2cc(C)nc3c2c(=O)[nH]n3C)c1 +CC(C)Oc1ncccc1NCc1csc(-c2ccccn2)n1 +COC(=O)c1c(NC(=O)c2cccnc2)sc2c1CCC2 +CCOC(=O)C(NC)c1nc2cc(O)ccc2n1C +O=c1ccc2cc(S(=O)(=O)NC3CC3)ccc2[nH]1 +CCC(C(=O)N1C2CCCC1COC2)c1ccccc1 +Nc1c(Nc2nccs2)ncnc1-n1nnc2ccccc21 +CS(=O)(=O)N1CCCC1c1nnc2n1CCCCC2 +Cc1ccc(S(=O)(=O)Cc2cc(F)ccc2N)cc1 +COc1ccc(C(=O)n2nc(-c3ccco3)nc2SC)cc1 +Cc1cc(COC(=O)c2ccc(NC(=O)c3ccco3)s2)on1 +Cc1oc(C)c(S(N)(=O)=O)c1C(=O)NCC1(c2ccccc2)CC1 +COc1ccc(C)cc1SC(C)C(=O)N1CCNCC1 +COc1ccc(-c2nnc(SCC#N)n2N)c(OC)c1 +O=S(=O)(c1ccccc1)N1CCCC1c1cccc(F)c1 +O=C(COc1ccccc1)Nc1ccc(N2CCNC2=O)cc1 +Cn1c(=O)[nH]c(=O)c2c1nc(N)n2Cc1ccc(Cl)c(Cl)c1 +Cc1ccccc1CN(C)C(=O)CCn1ccccc1=O +COc1cc2cc(C(=O)c3cc(C)ccc3O)cnc2cc1OC +NC(=O)C1CCN(C(=O)NC2CCCCc3ccccc32)CC1 +Cn1cnnc1Sc1ccc(NC(=O)c2cc(Cl)c[nH]2)cc1 +CCC(C)C(C)NS(=O)(=O)c1cccc(N)c1C +CN(CCOc1ccccc1)Cc1nc2sccc2c(=O)[nH]1 +O=C(NCc1cc(Br)ccc1F)c1cnn[nH]1 +CC(=O)Oc1ccc(C(=O)Cc2ccccc2)c(OC(C)=O)c1 +C=CCNC(=O)CN1CCN(c2nccc(C(F)(F)F)n2)CC1 +Cc1n[nH]cc1CNCCc1ccc2c(c1)OCCO2 +CC1(C)C(NC(=O)NCC2CN3CCCCC3CO2)C2CCOC21 +CC(C)Cc1nn2cc(-c3ccccc3)nc2s1 +CC1CCCCN1C(=O)Cn1cnc2ccccc2c1=O +O=C(Nc1ccccc1C(=O)Nc1nccs1)c1ccccc1F +CC(C)c1cccc(NC(=O)c2ccc(N)nn2)c1 +Cn1cnc(CNC(=O)c2c(F)cccc2F)n1 +CN(C)C(=O)c1ccc(NC(=O)COc2ccc(F)cc2)cc1 +c1ccc(CSc2ncnc3c2ncn3C2CCCCO2)cc1 +Cc1nc(C)c(C(=O)C(C#N)c2nc3ccccc3[nH]2)s1 +CCc1cc2c(NCCC(=O)N3CCCC3)ncnc2s1 +OCCCn1c(C2CC2)nc2cc3c(cc21)OCO3 +Cc1c(C(=O)NC2(c3cc(F)ccc3F)CC2)cnc2ccnn12 +O=C1CCC(COC(=O)CCNC(=O)c2ccco2)N1 +CNS(=O)(=O)c1cc(C(=O)NCCNc2ncccn2)n(C)c1 +N#Cc1cccnc1NCCNS(=O)(=O)c1ccccc1 +NC(=O)Nc1cccc(C(=O)N2CCC(C3OCCO3)CC2)c1 +CNC(=O)c1ccc(N(Cc2ccc(F)cc2)S(C)(=O)=O)cc1 +CS(=O)(=O)N1CCN(C(=O)c2ccc(-n3cnnn3)cc2)CC1 +CCOC(=O)CC1Cc2ccc3ccc(O)cc3c2C1=O +COCCOCC(=O)Nc1cc(Cl)c(C)cc1Br +CCc1nc2nnc3c(=O)n(-c4ccc(Cl)cc4)ccc3n2n1 +CC(C)(NC(=O)Nc1ccccc1)C(=O)Nc1ccsc1 +CCC1(CC)CCN(C(=O)c2cc(Cl)ccn2)CC1 +CC(Sc1nnc(-c2ccncc2)o1)c1c(F)cccc1F +Cc1ccc(C#N)c2nc(-c3cccc(Cl)c3)nn12 +COCC(=O)NC(Cc1ccc(F)cc1)c1ccc(OC)cc1 +CCc1noc(CC)c1CNC(=O)NCc1oc2ccccc2c1C +CCOc1ncccc1C(=O)Oc1ccc2c(C)cc(=O)oc2c1 +COC(=O)C(NC(=O)c1ccc(OC)c(F)c1)C(C)C +O=C(NCc1ccc(OCC(F)(F)F)cc1)c1ccncc1 +COc1ccc(Cl)cc1C(=O)Nc1nnc(-c2ccncc2)s1 +Cc1oc(-c2cccs2)nc1CC(=O)N1CCOC2CCCCC21 +Cc1ccc(NC(=O)c2ccc(NCC(O)c3ccco3)nc2)cc1 +C=CCCC(=O)NC(C)C(O)c1c(F)cccc1Cl +COC(=O)C(Sc1ncnc2c1cnn2C)c1ccccc1Cl +CN1c2ccccc2C(=O)NC1c1c(F)c(F)c(F)c(F)c1F +CCCn1c(C)ccc(-c2noc(CCCC(=O)N(C)C)n2)c1=O +C=C(C)Cn1c(SCC(O)CO)nc2c1c(=O)[nH]c(=O)n2C +N#Cc1ccc(OCC(=O)Nc2ccc(F)c(F)c2)cc1 +CN(CC1(CO)CCOCC1)c1nc(CO)nc2ccccc12 +O=C(NC1(c2cccc(Cl)c2)CC1)c1ccc[nH]1 +Cc1[nH]c(=O)[nH]c(=O)c1NC(=O)Cn1c(C)cc2ccccc21 +COc1cc2c(cc1OC)CN(c1nnnn1-c1ccccc1)CC2 +Cc1csc(NC(=O)CC2OC(=O)c3ccccc32)n1 +COc1cccc(C(=O)N(CCc2cccs2)Cc2ccoc2)c1 +CC(=O)NCCc1nc2ccccc2n1Cc1cc(C)ccc1C +CC(Nc1ncnc2c1cnn2C)c1ccccn1 +Nc1cccc(NS(=O)(=O)CCCc2ccccc2)c1 +O=C(NCCCOCC1CCOC1)N1CCC2(CCCCC2)C1 +Cn1c(=O)c2ccn(CC(=O)NCc3ccccc3)c2n(C)c1=O +CCNC(=O)CNCc1cccc(OC2CCCC2)c1 +O=C1CNc2cccc(Cl)c2N1c1cccc(F)c1 +Cc1nc(C)c(C(=O)Nc2ccc(F)c(C#N)c2)s1 +COCCOc1ccccc1NC(=O)c1cc(C)n(C(C)C)c1C +Cc1ccc(CNS(=O)(=O)c2cncc(Br)c2)s1 +CN(C(=O)Cc1cccs1)C(C#N)c1ccc2c(c1)OCO2 +Cc1n[nH]cc1CNc1cccc(S(C)(=O)=O)c1 +Cc1nc(N2CCN(c3ncccc3F)CC2)sc1C +CCC(C)n1ncc2cc(C(=O)NC3CC3)c(N)nc21 +CCNC(=O)c1ccccc1NC(=O)COc1ccc(OC)cc1 +CC(C(=O)NCc1ccccn1)n1ccc(C(F)(F)F)n1 +O=C1C=C(c2ccc(F)cc2)Nc2ccccc2N1 +Oc1ccc2c(c1)NCC(Cc1ccc3c(c1)OCO3)O2 +CN1C(=O)CCC(C(=O)NCCc2ccccc2)C1c1cccs1 +CCCNC(=O)C1CCCN(C(=O)c2ccc(C(C)=O)cc2)C1 +Cc1cc(S(=O)(=O)N(C)Cc2ccccn2)c(C)s1 +Cc1csc(C(C)NC(=O)CCn2c(C)cc(C)nc2=O)n1 +COc1ccccc1NC(=O)Cn1ccnc1-c1cnccn1 +CC(C)Cn1nnc(C#N)c1C(Cl)(Cl)Cl +Cc1noc(CNC(=O)Cc2csc(NC(=O)C3CC3)n2)n1 +O=C(CNCC(F)(F)F)NC1CCN(c2c(F)cccc2F)C1 +Cc1nc(CN2CCC3OC(COCC(C)C)CCC32)cs1 +CC(CC(=O)NC(C)(C)C(N)=O)C(=O)c1cccc(F)c1 +CCN(C(C)=O)c1nc(CSc2nc(C)cc(N)n2)cs1 +Cc1cccc(OCC(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)c1 +CC(=O)c1ccc(NS(=O)(=O)c2ccccc2O)cc1 +COCc1cc(=O)[nH]c(Nc2ccc(F)c(Cl)c2)n1 +COc1ccccc1CNC(=O)c1c[nH]c2cccc(F)c12 +Cc1cc(OC(F)F)c(C(=O)Nc2cccc(C)c2C(N)=O)s1 +Cc1ccc(C(=O)NCCNC(=O)c2ccc(C)c(F)c2)s1 +COCCN(C)C(=O)C1CCN(c2cc(F)cc(F)c2)C1=O +CC(C)CNC(=O)NC1CCCc2[nH]c(=O)ccc21 +O=S1(=O)CCCN1CCCOc1ccc(F)cc1Cl +CCOc1ccc(Nc2ccc3nnnn3n2)cc1F +CCCn1ncc(S(=O)(=O)NCC(C)C)c1N +COC(=O)CCCn1cnc2sc(C)c(C)c2c1=O +CC1CC1c1ccc(CN(C)C(C(N)=O)c2cccc(F)c2)o1 +COCC(C)OC(=O)c1cccc(NC(=O)C2CC2)c1 +CCCCC(NC(N)=O)C(=O)Nc1cc(Br)ccc1C +Cn1cc(CNc2nc3ccccc3o2)c(-c2cccnc2)n1 +O=C(c1cc(F)cc(F)c1)N1CCC2(CC1)CC2 +CC(C)C(C)NC(=O)NCc1ccc(S(C)(=O)=O)cc1 +CC(C(=O)N(C)CC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1)n1cccn1 +O=C(NCC(O)c1ccco1)Nc1nccs1 +Cc1cc(NC(=O)Cn2ccc3cccnc32)n(C(C)C)n1 +CC(C)(CNC(=O)Cc1ccc(F)c(F)c1)NS(C)(=O)=O +Cc1cc(SCc2noc(C)n2)c2ccccc2n1 +Cc1ccc(CNc2cnn(CC(F)(F)F)c2)o1 +Cc1cccc(C(C(=O)N(Cc2cncs2)C2CC2)N(C)C)c1 +O=C(NCc1ncccc1F)Nc1ccn(-c2ncccc2Cl)n1 +Cc1nc(-c2ccc3c(c2)CCN3C(=O)C2CCC(=O)NC2)cs1 +CCC(C)NS(=O)(=O)Cc1cccc(NC(=O)c2ccccc2)c1 +CC(=O)c1csc(NC(=O)c2cccc(=O)n2C)n1 +CCNC(=O)c1cc(S(=O)(=O)Nc2cccnc2)c(C)s1 +Cc1ccc(C(=O)NC(c2ccccc2)c2nccn2C)o1 +CCc1ccc(C(=O)NCCCc2nc(-c3ccncc3)cs2)o1 +O=C(Cn1cnc2ccccc21)NC1CCOCC1 +CCC(C)CS(=O)(=O)c1nnc(NCC(C)C)s1 +Cc1occc1C(=O)NCC(CC(C)C)N1CCOCC1 +OC1CN(Cc2cc(C3CCCCC3)no2)Cc2ccccc21 +CCOC(=O)C1CCCN(C(=O)NCc2ccc(C)cc2N(C)C)C1 +COCC(=O)N1CCN(C(=O)Nc2cc(-c3ccccc3)on2)CC1 +Cc1cccc(CNC(=O)COc2cc(C)ccc2F)c1 +CCC(=O)Nc1cc(F)ccc1SCC(F)F +O=C(NCCCN1CCCC1=O)C1CN(C(=O)c2cnccn2)C1 +CCCOc1c(Cl)cc(C(=O)N(CC)CC)cc1OC +COc1cccc(Cc2nc3ccccn3c2CO)c1 +COc1cccc(-c2cc(-c3nc(-c4ccccn4)no3)[nH]n2)c1 +CC(C)CNS(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CC(=O)Nc1ccc(C2Nc3ccc(Cl)cc3C(=O)N2C)cc1 +Cn1cc(C(=O)NCC2CCN(c3ccc(F)cc3)C2)cn1 +Cn1c(=O)[nH]c(N2CCCC2)c(Cc2ccc3ccccc3c2)c1=O +COCc1cccc(C(=O)Nc2ccccc2SCCC#N)c1 +c1ccc2oc(N3CCCC(c4ccn[nH]4)C3)nc2c1 +COCCC(=O)NC1CCN(c2ccc(C)cc2)C1=O +C=CCOc1ccc2c(C)c(CC(C)O)c(=O)oc2c1 +CCCc1cc(C(=O)NCc2cccnc2)cs1 +CCOCCNC(=O)N1CCC(C(=O)c2ccccc2)CC1 +CCC1=C(C(=O)OC)C(c2ccc(F)cc2)n2nnnc2N1 +Cc1cc(NC(=O)c2cccc(Br)c2)ccn1 +O=C(NC1CCCc2c1cnn2-c1ccncc1)C1CCCO1 +CC(C)S(=O)(=O)NCCn1nc(-n2cccn2)ccc1=O +C=CCNC(=O)Nc1ccc(NC(=O)CSc2ccncc2)cc1 +CCn1cc(Br)cc1C(=O)NC1CCCC(O)C1 +Cc1cccn2c(=O)c(C(=O)NCc3ccc(Cl)cc3)c(O)nc12 +Cc1ccc(OCCNC(=O)c2cccc(N3CCCC3=O)c2)cc1 +O=C(c1c(F)cccc1F)N1CCC(Nc2cccnc2)C1 +CN(C)Cc1cc(=O)c(O)cn1Cc1ccccc1Cl +COc1ccc(F)cc1NC(=O)CCCc1nc(C)no1 +CCC(C)N(C)C(=O)CSc1ccc(F)cc1 +Cc1cc2nnc(SCc3noc(-c4ccco4)n3)n2c(C)n1 +COc1ccc(CNC(=O)c2ccc(-c3cccnc3)nc2)c(OC)c1 +CC(=O)Nc1cccc(C(=O)Nc2ccc(Br)cc2)c1 +CC(Sc1ccccc1)C(=O)Nc1ccnn1C(C)C +CCC(C)NC(=O)c1nc2cc(C)c(C)cc2n(C)c1=O +COc1cc2c(c(OC)c1)C(c1cncc(C)c1)NCC2 +O=C(CCc1cnccn1)N1CCN(c2ccc(F)cc2)CC1 +COC(=O)C(Cc1ccccc1)NC(=O)c1cc(C(C)C)no1 +CCCc1n[nH]cc1C(=O)N1CCN(CCOc2ccccc2)CC1 +CCN1CCN(S(=O)(=O)c2cc(C)c(OC)cc2C)CC1 +CN(CCO)C(=O)Nc1ccc(SC(C)(C)C)cc1 +CC(=O)c1c(C)nc(C)nc1SCCCNS(C)(=O)=O +CC1CC(c2ccc(F)cc2)CN1Cc1cnnn1C +CCn1cc(Br)cc1C(=O)N(CCC#N)C(C)C +Cc1cnc(NC(=O)c2cc3cc(F)ccc3s2)s1 +COc1ccccc1C(O)c1ccc2c(c1)CCC(=O)N2C +Cc1cc(NC(=O)C(C)N2CCn3c(nn(C)c3=O)C2)on1 +CSc1cc(C(=O)NCCCN2CC(C)OC(C)C2)ccn1 +CCCC1CN(C(=O)C2CCCN(S(=O)(=O)CCC)C2)CCO1 +COC(=O)CCCC(=O)c1cc(C)cc(Cl)c1OC +NC(=O)CCCNC(=O)CCc1cccc(F)c1 +Cc1ccc(-n2nnnc2CNS(C)(=O)=O)cc1 +CCOC(=O)N1CCN(c2ccc3nncn3n2)CC1 +O=C(CCCOc1ccccc1Cl)NCc1nnc2n1CCC2 +COc1ccc(C(=O)Nc2nnc(Cc3cccs3)o2)cc1OC +Cc1ccc(N2Cc3ccc(N)cc3C2=O)cc1Cl +CCn1cnnc1CNC(=O)Nc1ccccc1C#Cc1ccccc1 +CCc1[nH]c(SCC(=O)Nc2ncccn2)nc1C +CCOc1ccccc1NC(=O)Cn1ccc2sc(C)cc2c1=O +O=C(CCNC(=O)c1ccc(F)cc1F)OC1CCCCC1 +Cc1ccc2c(c1)CCN2S(=O)(=O)c1ccc2oc(=O)ccc2c1 +NC(=O)CC1CCN(C(=O)c2cc3c([nH]c2=O)CCC3)CC1 +COC(=O)c1cc(-c2ccc(OC)cc2C)nn1-c1ccccn1 +CC(C)(C)n1cc(Nc2cnc3ccccc3n2)cn1 +CS(=O)(=O)NC(Cc1ccccc1)c1cccs1 +CC(C)N(C)S(=O)(=O)c1ccc(NC(=O)NC(C)(C)C)cc1 +CCC(C)OCC(=O)Nc1cc(-c2ncco2)ccc1C +Cc1cc(=O)n(CCNC(=O)c2ccccc2Cl)cn1 +CCOC(=O)c1c(C)nn(CC2CCCCC2)c1N +Cc1cccc2nc(C(=O)Nc3ccc(C#N)c(Cl)c3)cn12 +O=C(NCc1cn[nH]c1)c1cc2c(s1)CCCCC2 +Cc1cc(C)n2nc(CC(=O)Oc3c(C)cccc3C)nc2n1 +COc1ccc(C(=O)Nc2ncc(C(F)(F)F)cc2Cl)cc1 +CCNC(=O)C1CCCN(C(=O)NC2CCCC(CC)C2)C1 +Nc1nncc(-c2ccc3c(c2)CCCC3)c1C(=O)NC1CC1 +COc1ccc(OC)c(C(=O)NCCC(C)C)c1 +c1ccc(OCC2CC2)c(NCc2nnc(C3CCC3)o2)c1 +CCC(=O)Nc1ccc(S(=O)(=O)N=c2cc(C)cc[nH]2)cc1 +Cc1ccc(CC(=O)N2CCC3(CCC(=O)N(C4CC4)C3)CC2)cc1 +CCOCc1cccc(NC(=O)c2ccccc2COC)c1 +CC(=O)N1CCN(Cc2cc(=O)c3cc(C)cc(C)c3[nH]2)CC1 +COC(=O)CNS(=O)(=O)c1cscc1C(=O)OC +CC1CC(C)CN(C(=O)CC2Oc3ccccc3NC2=O)C1 +CCc1cc(NC(=O)N2CCN(c3cccs3)CC2)n(C)n1 +O=C(Nc1cnc2ccccc2c1)c1ccc2cc[nH]c2n1 +Nc1c(Br)ccc2c(C(=O)N3CCCC3)nccc12 +CCOc1cc(F)ccc1NCc1nc(C)no1 +CCCn1c(SC(C)C)nnc1-c1ccncc1 +Cc1cc(NC(=O)Cn2nnc(-c3cccs3)n2)n(C)n1 +CC(=O)NCc1ccc(S(=O)(=O)N2CCN(C(C)=O)CC2)cc1 +CN(CCC#N)C(=O)CSc1nnc(-c2cccs2)n1C1CC1 +Cn1nnnc1SCC(=O)N(Cc1ccccc1F)C1CC1 +CCCOc1ccc(-c2ncc(CO)s2)cc1OCC +CC(CC(=O)N1CCC(C(=O)N2CCCC2)CC1)c1ccccc1F +O=c1c(=Cc2ccccc2Cl)sc2ncnn12 +COc1ccc(CCNC(=O)c2ccc(N)c(OC)c2)cc1 +O=C(CCn1cncn1)N1CCN(c2ccc(F)cc2)CC1 +CN(CC(=O)NC1CC1)C(=O)c1cc(N2CCCC2=O)ccc1Cl +CCN(CC)C(=O)CCC(=O)N(c1ccc(F)cc1)C(C)C +COc1cc(CNC(=O)c2cccnc2SC)cc(OC)c1OC +N#Cc1cccc(C(=O)N2CCc3ncnc(-c4ccoc4)c3CC2)c1 +COCCn1c(C)c(C)c2c1ncn1c3ccccc3nc21 +Cc1nc(SCCN2CCOCC2)cc(-c2ccccc2)n1 +CC(C)(C)OC(=O)NCC(O)c1ccc(Cl)c(F)c1 +CCCC1CCC(NC(=O)C2CCN(S(=O)(=O)CC)CC2)CC1 +CC(C)c1ccc(OCCNS(C)(=O)=O)cc1 +O=C(NCCS(=O)(=O)c1ccc(F)cc1)Nc1ccccc1 +O=c1[nH]c2ccccc2c(=O)n1Cc1cnn(-c2ccccc2)c1 +CCCN(CC(F)(F)F)C(=O)c1ccc(N)nn1 +COc1ccccc1-c1noc(-c2cn(C)c3ccccc3c2=O)n1 +Cn1ncc(Br)c1NC(=O)c1ccc(Cl)cc1 +COc1ccc(CNC(=O)c2cc(Cl)ccc2F)c(OC)c1 +Cc1ccc(C)c(NCc2nnc(-c3ccccc3)o2)c1 +Cc1ccc(CN2CC3CC(C(=O)NCC4CC4)C(C2)O3)cc1 +O=S(=O)(c1ccc(F)c(Cl)c1)N1CCCCCC1 +C=CCN(CCc1ccccc1)C(=O)NCc1cc(C)on1 +Cc1cc(NC(=O)NCC(=O)NC2CC2)ccc1-n1cnnn1 +Cc1nc(-c2cccs2)sc1CNC(=O)C1CCC1 +O=C(c1cc2ccccc2[nH]1)N(CC(F)F)C1CC1 +CN(CC(F)(F)F)S(=O)(=O)c1ccc2c(c1)CCN2 +COc1ccc(F)cc1NC(=O)Cc1c(C)nc2nc(N)nn2c1C +CC(=O)N(Cc1nc(-c2ccc(C)cc2)no1)C(C)C +N#CC(C(=O)C1(c2ccc(F)cc2F)CCCC1)c1ccc(F)cn1 +COCCNC(=O)Nc1ccc(=O)n(CCOC)c1 +CCSc1ccc(NC(=O)c2csnn2)cn1 +CCc1nc(CNC(=O)N2CCc3ccccc3C2CO)cs1 +CC(C)Cn1nccc1NC(=O)CSc1ccccc1Cl +CCCCn1nnnc1CN1CCc2c(N)cccc2C1 +NC(c1ccc(Cl)cc1)c1nc2c(s1)CCCC2 +Cc1cc(C(C)(C)C)cc(C)c1CCNC(=O)Cn1cnnc1C#N +CCOc1ccccc1NCC(O)c1ccc(C)c(N)c1 +CN(Cc1ccccc1)C(=O)NCCCn1nc2n(c1=O)CCCC2 +Cc1cc(C(C)NS(=O)(=O)c2ccccc2C#N)c(C)o1 +CC(C)S(=O)(=O)c1noc(C(=O)Nc2ccccn2)c1N +CC1COC(c2ccccc2)C(C)N1Cc1cc[nH]n1 +CSc1ccc(S(=O)(=O)NCCCN2CCOCC2)cc1 +COC1CCCC1OC(=O)CCn1ncc(=O)c2ccccc21 +COCCC1(C(=O)NCc2ncn(C)n2)CCCC1 +Cc1ccc(N2CCC3(CC2)CN(Cc2ccccc2)C3=O)nn1 +COc1ccc(F)cc1NC(=O)NC(C)C1CN(C)CCO1 +CCc1onc(C)c1NC(=O)C(C)CSc1ccccc1 +CCc1nc2cc(Br)c(N)cc2n1CC +Cc1noc(CC2COC3CN(C(=O)c4cnccn4)CC23)n1 +Cn1cccc1-c1cn2cc(Br)ccc2n1 +CCCNC(=O)CN1C(=O)C(C)Oc2cc(O)ccc21 +O=C(NC1CC(=O)N(c2ccccc2)C1)c1cc2ccccc2c(=O)[nH]1 +CCCC(C)(C)NC(=O)c1csc(-c2cnn(C)c2)n1 +CCNC(=O)c1cccc(NCc2cc(Br)cs2)c1 +CC1C(=O)Nc2ccccc2N1C(=O)c1cccc(OCC(F)F)n1 +CCC(=O)Nc1cccc(NC(=O)C2CCN(C(C)=O)CC2)c1 +CC(OC(=O)c1cccn1C)C(=O)Nc1sccc1C#N +Cc1nc(C)n(CCSc2ncc(C(F)(F)F)cc2Cl)n1 +C=CCNC(=O)N1CCN(c2ccccc2OC)CC1 +NC(=O)Cc1nccc2c(Cl)c(Cl)ccc12 +COc1cc(CNC(=O)c2scnc2C)ccc1OC1CCCC1 +COc1ccc(C(=O)Nc2cccc(NC(=O)C(C)C)c2)cc1 +CC(=O)NC(C(=O)Nc1cccc(C(F)(F)F)c1)C(C)C +O=C(NCCNC(=O)C1CC(=O)N(c2ccccc2)C1)C1CC1 +COC(=O)CC(N)C(=O)c1ccc2ccccc2c1 +CC(=O)Nc1nnc(SCc2cccc3ccccc23)s1 +O=C(COc1ccc(Cl)cc1)NCCCN1CCCC1=O +COc1ccc(NC(=O)c2nc(-c3ccncc3)no2)c(OC)c1 +N#Cc1cccc(NC(=O)COc2cccc(-n3ccnc3)c2)c1 +COC(=O)c1ccc(Cn2cnc3c(C)cccc3c2=O)cc1 +Clc1ccc(-c2nnc(-c3cccnc3)o2)cc1 +CCC(CC)CNC(=O)NCC1CN2CCCCC2CO1 +Cc1cc(Sc2nnc(C)s2)c2ccccc2n1 +CNC(=O)c1cc2occc2n1Cc1ccccc1 +CNC(=O)CNC(=O)c1cc2ccc(Cl)cc2n1C +Cn1c(CCNc2nnc(C3CC3)o2)nc2ccccc21 +N#CCc1c(-c2cccnc2)nc2c(Cl)cccn12 +CCCOc1cc(CO)cc2c1OC(C)(C)C(=O)N2CC(N)=O +Cc1cccc(CNC(=O)Nc2nnc(C(C)C)s2)n1 +O=C(c1cnn2cccnc12)N1CCn2c(nnc2-c2ccccc2)C1 +CC(OC(=O)CCc1nc(-c2cccs2)no1)C(N)=O +COC(=O)c1c(-c2cccnc2)csc1NC(=O)c1cc(C)on1 +COc1ccc(OCCN(C)C(=O)c2cccc(OC)c2)cc1 +CC(Sc1nccn1C)C(=O)Nc1cc(Cl)cc(Cl)c1 +CCOCCC(=O)Nc1ccc2[nH]c(C3CCCO3)nc2c1 +Cc1ccc(Sc2ncnc(N3CCCC3)c2N)cc1 +NC(=O)C1CCCN1C(=O)c1ccc(OCC2CCCO2)cc1 +CC(C)=CCCC1(C)CCC(=O)N(CCc2nc(C)cc(=O)[nH]2)C1 +COc1ccc(C)cc1NC(=O)C(C)N1CCc2cc(F)ccc2C1 +CCC(=O)Nn1cnc2c(cnn2-c2ccc(F)cc2)c1=O +CNC(=O)C(C)(C)CNC(=O)Nc1cc(C)ccn1 +O=C(NCc1ccc(F)cc1)NC1CCN(c2ccccc2)CC1 +CC1CN(Cc2cn3ccsc3n2)CC(C)O1 +Cn1c(NC2CCN(C(=O)C3CC3)CC2)c(C#N)c(=O)n(C)c1=O +Cc1ccc2ncc(C(=O)Nc3cccc(-n4nnnc4C)c3)n2c1 +O=C(Cn1cccn1)NCC(c1cccs1)N1CCOCC1 +Nc1ccc(F)c2ccnc(C(=O)NC3CCCCC3)c12 +COc1cc(CN(C)c2ccc3nnnn3n2)ccc1OC(F)F +CC(C)Oc1nc(OCc2cccs2)ccc1N +CC(NC(N)=O)C(=O)N(C)CCCOc1ccc(F)cc1 +Cc1nnc(-c2ccc(C(=O)N3CCOc4ccc(F)cc43)cc2)o1 +Cc1cc(=O)n(CC(=O)N(Cc2ccccc2)c2ccccc2)cn1 +NS(=O)(=O)NCC1(c2cccc(C(F)(F)F)c2)CCOCC1 +CCOC(=O)N1CCN(C(=O)C2CC2c2ccc(F)cc2)CC1 +Cc1nnc(SCC(=O)NC2(C#N)CCCC2)n1C1CCCCC1 +Cc1cc2ncn(CC(O)c3ccc4c(c3)OCCO4)c2cc1C +Cc1ccc2ncc(-c3nc(CC(C)C)no3)n2c1 +CCCCN(CCO)C(=O)Nc1ccc(Cl)c(C(=O)NC)c1 +Cc1cc(C)nc(N2CCC(O)(c3ccccc3F)CC2)n1 +CCn1nc(C(=O)Nc2nnc(-c3ccccc3OC)o2)cc1C +OC(CNCc1nc(-c2ccccc2)cs1)c1c(F)cccc1F +Cc1cccc(Cl)c1NCc1cccc(C(=O)N(C)C)c1 +CN(c1c(F)cccc1F)S(=O)(=O)c1ccc(C#N)cc1 +CC1CN(C(=O)c2cccn2Cc2cccs2)CC(C)O1 +CC(C)OCCCNC(=O)c1ccc2c(c1)n(C)c(=O)c1ccnn12 +CCC(=O)c1ccc(OCC(=O)Nc2cccc(C(N)=O)c2)cc1 +COCCNC(=O)N1CCC(CNC(C)=O)CC1 +O=C(NCc1ccco1)c1sc(-n2cccc2)nc1-c1ccccc1 +CNC(=O)COc1ccc(C(=O)Nc2cccc(C)c2C)cc1OC +Cc1cc2c(=O)n(CCCc3ccccc3)cnc2s1 +NC(=O)C1CCN(C(=O)NCCc2ccc3c(c2)OCCO3)CC1 +CC(=O)Nc1ccc(O)c(C(=O)NC(C)c2ccc(C)c(F)c2)c1 +CCOC(=O)c1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)cc1 +O=c1c(Cl)c(N2CCCCC2)cnn1Cc1ccc(F)cc1 +Cc1cccc(NC(=O)c2cc3cc(F)ccc3[nH]2)n1 +Cc1cc(N)cc2c(CC(=O)Nc3ccccc3C#N)noc12 +CNC(=O)c1cccc(CCC(=O)Nc2ccc(C(C)=O)c(C)c2)c1 +CS(=O)(=O)N1CCC2(CCN(C(=O)c3ccsc3)CC2)CC1 +COc1cc(OC)c2[nH]c(C(=O)Nc3ccn(C)n3)cc2c1 +Cc1cc(C)n(C2CN(CCC(=O)NCCc3ccccc3)C2)n1 +Cc1cc(C)n(CCCNS(=O)(=O)c2ccc(F)c(Cl)c2)n1 +CCCn1cc(-c2cc(C(=O)NC(C)C)c3ccc(F)cc3n2)cn1 +CN(Cc1ccc(F)cc1F)C(=O)COc1ccccc1F +COc1ccc2[nH]cc(C(=O)NCCC(=O)N3CCOCC3)c2n1 +Cc1csc(CN2CCN(C(=O)CC(C)C)CC2)n1 +CCS(=O)(=O)NCCNc1nn2cc(C(C)(C)C)nc2s1 +NS(=O)(=O)CCCNC(=O)c1c(O)cc(F)cc1F +COc1ccc(C(=O)NCc2cc[nH]n2)cc1-c1ccccc1 +CC(C)Cc1noc(-c2ccc(N(C)CCO)nc2)n1 +COCC(=O)NCC(c1ccc(OC)cc1)c1c[nH]c2ccccc12 +COc1cc(Cl)c(C)cc1NC(=O)C1CC=CC1 +CC(C)N(Cc1ccc(C#N)cc1)C(=O)c1ncn(-c2ccccc2)n1 +CC(C)(C)c1ccc(=O)n(Cc2ccccc2C#N)n1 +Cc1c(C(=O)N(C)CC(=O)NC(C)(C)C)sc2ccc(F)cc12 +O=C1CCC(NS(=O)(=O)c2ccccc2Br)CN1 +COC(=O)c1sccc1NC(=O)c1ccccc1OC +CCCNC(=O)CCNC(=O)Nc1ccc(C(C)=O)cc1 +C=CCc1cc(CNC(=O)c2cnccn2)cc(OC)c1OC +C=CCNC(=O)Cc1csc(NC(=O)Nc2ccccc2)n1 +CC(=O)Nc1nc(C(=O)Oc2ccc(C(F)(F)F)cc2)cs1 +CCOC(=O)N1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +Cc1csc(C2CCCCN2C(=O)COC2CCCC2)n1 +CCCNS(=O)(=O)c1ccc(OCC(=O)N2CCOCC2)cc1 +CCNC(=O)C1CCCN(C(=O)Nc2ccc(OCC)c(C)c2)C1 +NC(=O)COc1cccc(NC(=O)c2ccc(F)cc2)c1 +O=C(CCOC1CCOCC1)N(CC1CC1)C1CCCCC1 +Cc1nc(C)c(CC(=O)NC(C)Cc2ccco2)c(=O)[nH]1 +CC(C)(C)c1ncc(C(=O)N2CCN(c3ncccn3)CC2)s1 +CCCSc1nc2[nH]c(C)c(CCO)c(=O)n2n1 +CS(=O)(=O)Nc1ccc(C(=O)NCc2ccccn2)cc1 +Cc1csc(NC(=O)COC(=O)c2cc(=O)c3ccccc3o2)n1 +C=CCNC(=O)CNc1cccc(C(=O)NC(C)(C)C)c1 +COc1ccc(NC(=O)NCc2ccc(S(N)(=O)=O)cc2)cn1 +CS(=O)(=O)c1cc(N)c(OC(F)(F)F)cc1Br +Cc1cccc2c1C(C(=O)Cc1ccc(O)cc1)NCC2 +O=C(CCNC(=O)C1CCCC1)Nc1ccc(F)cc1F +COCC1(C(=O)N2CCCC2c2ccccc2C)CCC1 +CCc1ccc(C(C)CC(=O)N2CCC(C(N)=O)CC2)cc1 +Cc1ccc(C(C)N(C)C(=O)NCCN2CCOCC2)cc1 +O=C(Cn1ncc2ccccc2c1=O)NCc1ccc(Cl)cc1 +CCc1nc(C)sc1Cn1cc(-c2cn(CC)nc2C)nn1 +COc1ccc(C2CC(c3ccccc3OC)n3ncnc3N2)cc1 +CCS(=O)(=O)c1cccc(S(=O)(=O)Nc2c[nH]nc2C)c1 +CCNC(=O)c1ccc(CNC(=O)c2cn(-c3ccccc3)nn2)cc1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3noc4c3CCCC4)cc12 +O=S(=O)(NCCn1nc(C2CC2)cc1C1CC1)C1CC1 +COc1c(F)ccc2c1CCNC2c1cncn1C +Cc1nc2ccccc2n1CCNC(=O)c1ccc(=O)n(C)c1 +COc1ccc(Cl)cc1NC(=O)CCCCO +C=CCOc1ccccc1CNC(=O)NCC(=O)N1CCCCC1 +CC1COCCN1C(=O)c1ccc2ncsc2c1 +CCc1noc(CC)c1CC(=O)Nc1cc(F)ccc1C +Cc1ccc(S(=O)(=O)NC(=O)NCc2ccncc2)cc1 +O=C(NC1C2Cc3ccccc3C21)c1ccnc(OC2CCOC2)c1 +N#Cc1ncc(C(F)(F)F)cc1Br +O=C(CCn1nnc2ccccc2c1=O)NCCc1ccccn1 +CC(=O)N1CCC(CCC(=O)NC(C(N)=O)C(C)(C)C)CC1 +CC(C)OCCCNC(=O)c1cccc(S(C)(=O)=O)c1 +CN(Cc1nc(-c2ccccc2)no1)S(C)(=O)=O +Cc1cccc(CN2CCOC3CCC2C3OCc2cccnc2)n1 +Cc1noc(C)c1CC(=O)NCC#CCOc1cccnc1 +O=C(CCn1c(=O)oc2ccccc21)OCC(=O)c1ccc[nH]1 +Cn1nc(CNC(=O)Nc2ccc3c(c2)OCO3)c2c1CCCC2 +C=CCN(Cc1cccs1)C(=O)CNc1c(C)cccc1C +CC(NC(=O)CSc1nncs1)C(=O)N1CCCC1 +COCCn1cc(C(=O)NCCc2ccccc2F)ccc1=O +CC(C#N)CN1CCN(c2cccc(Cl)c2)CC1 +CC(=O)Nc1ccc(NS(=O)(=O)c2ccccc2C)cc1 +CCCC(C)NC(=O)c1cccc(NC(=O)CC)c1 +Cc1onc(-c2ccccc2)c1C(=O)OCC1CCCO1 +CC1CN(C(=O)NCCNC(=O)c2ccc(Cl)cc2)CC(C)O1 +Cn1ccc2ccc(NC(=O)c3cccc(N4CCCNC4=O)c3)cc21 +CCN1CCN(S(=O)(=O)N2CCOCC2)CC1 +COc1ccc(-c2noc(CC(=O)NCc3ccc(F)cc3)n2)cc1 +C=CCn1c(SCCCC)nnc1-c1cccnc1 +Cc1n[nH]c2ncc(NC(=O)c3cccc(=O)n3C)cc12 +Cc1cc(C)n(CC2CCCN2C(=O)COC2CCCCC2)n1 +O=C1NCCN(C(=O)Nc2ccc(OC(F)(F)F)cc2)C1CCO +CCCn1c(C)cc(C(=O)CSc2nncn2C)c1C +COc1ncccc1C(=O)NC1CC(=O)N(CC(C)(C)C)C1 +CCC1CCC(NC(=O)N2CCCC(NS(C)(=O)=O)C2)CC1 +Cc1nc(N(C)CCc2cn[nH]c2)c2nc(C)oc2n1 +CC1CCC(N(C)C(=O)COc2ncnc3sccc23)CC1 +Cc1ccc(NC(=O)CCNC(=O)c2ccccc2)cc1C +CCN(CC)S(=O)(=O)c1ccc(N(C)C)c(NC(C)=O)c1 +COc1ccc(C(C)NC(=O)Cn2ccccc2=O)cc1F +O=C(Nc1ccc(NC(=O)C2CC2)nc1)c1cnoc1-c1ccccc1 +CC(=O)c1ccc2c(c1)N(CCCOc1cccc(C)c1)C(=O)CO2 +Cc1c(CNCCc2nc(-c3ccccn3)cs2)cc(C#N)n1C +CCOC(=O)CN(CC)C(=O)c1c[nH]c(=O)[nH]c1=O +COc1ccc(C)cc1C(C)NC(=O)Nc1nc(C2CC2)cs1 +CCCNC(=O)Nc1cnn(-c2ccccc2S(C)(=O)=O)c1 +CCC(C)NC(=O)c1cc(-c2ccc(OC)c(OC)c2)no1 +CS(=O)(=O)c1ccc(NCC(=O)NCC2CC2)cc1 +O=C(NCC1CC1)C1CCCN(C(=O)Cc2noc3ccccc23)C1 +Cn1c(SCC(=O)NC(C)(C)C)nnc1C1CCCCC1 +Cc1ccc(C2=CCN(S(=O)(=O)c3ccccc3F)CC2)o1 +CCC(C)c1ccc(NC(=O)COC(=O)c2cnc(C)cn2)cc1 +Cc1occc1-c1nnc(SCC(=O)N2CCCCCC2)n1N +CN(C(=O)COc1ccc(Cl)cc1)C1(C#N)CCCC1 +NC(=O)CCCNC(=O)c1ccc(N2CCCCC2=O)cc1 +CCN(CC)C(=O)c1cccc(NC(=O)c2cnc(C)cn2)c1 +O=C1CCN(C(=O)c2cc(Br)ccc2F)CC1 +O=C1NCCN1C1CCN(C(=O)C2(c3ccc(F)cc3)CCC2)CC1 +CC1CCCN(C(=O)c2ccc3c(c2)CCCN3S(C)(=O)=O)C1 +CCN(CC(=O)OC)C(=O)c1cccc(OC)c1O +CC(=O)c1ccc(NC(=O)CSc2cn[nH]n2)cc1 +CCC(CC)NC(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +CC(C)(C)OC(=O)N1CCC(C(=O)NC2CC2)CC1 +CCCc1cc(C2CCCN2S(=O)(=O)c2c(C)noc2C)no1 +CC(C)C(=O)NC(C)c1cc2c(cc1Br)OCCO2 +C#CCOC(=O)COC(c1ccccc1)c1ccccc1 +COCc1c(C#N)nnn1CCOc1ccc(C)cc1 +Cc1ccccc1-c1ncc(C(=O)Nc2ccccn2)c(N)n1 +COCCOCC(=O)N1CCN(C(=O)c2ccccc2)CC1 +CCOCc1ccccc1CNC(=O)c1n[nH]c(=O)[nH]1 +CC(CCCO)NC(=O)N1CCCN(C(=O)c2cccs2)CC1 +Cc1cc(C)cc(NC(=O)COC(=O)c2cc(C)oc2C)c1 +Fc1ccc2c(c1)CCCC2Nc1ncnc2ncccc12 +CC(C)(C)C(=O)COC(=O)c1ccc(Cl)c(N)c1 +CNC(=O)C1CCCCN1C(=O)c1cnc(C)cn1 +CCc1nc2cc(NCc3cncs3)ccc2o1 +CC(NC(=O)Cc1c[nH]c2ncccc12)c1ccccn1 +CC1=Nc2ncnn2C(c2ccccc2F)C1C(N)=O +Cc1nn(C(=O)NCC2CCCCC2)c(=O)n1N +O=C(Nc1cccc(O)c1)c1ccnc(OC2CCC2)c1 +Cc1cccc(OC(C)C(=O)Nc2nccs2)c1 +COCCn1c(CN(C)C(=O)c2ccco2)nc2ccccc21 +CC(Sc1n[nH]c(N)n1)C(=O)NC(C)(C#N)C(C)C +COCCN(C)C(=O)c1sccc1-n1cnnn1 +C#CCn1cnc2c(nnn2-c2ccc(C)c(Cl)c2)c1=O +Cc1ccccc1-n1ccnc1SCC(=O)n1ncc(C#N)c1N +Cc1ccc(NCc2nc(C)cs2)c(OCC2CCCO2)c1 +CC(Nc1ccc2c(c1)CCC2)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +CN(C)c1cccc(C(=O)NC2CCCCC2O)c1 +CCCCn1nc(C(=O)N2CC3CC4CC(C3)CC2C4)ccc1=O +Cc1nc2ccccn2c1C(=O)NCc1ccccc1 +COc1cc(OC)cc(C(=O)NCC(OC)c2ccsc2)c1 +Cc1noc(C)c1C(=O)Oc1ccc2c(c1)OCO2 +O=C(Nc1cnc(N2CCCC2)nc1)Nc1ccc2c(c1)OCCO2 +CNC(=O)CCNC(=O)Nc1c(C)cc(Br)cc1Cl +COCCNC(=O)c1cc(Br)cs1 +COc1ccc(C(=O)Nc2cccc(N)c2)c(O)c1 +Cc1nn(C)c2ncc(NC(=O)COc3ccc(C#N)cc3)cc12 +COc1ccc(CC(=O)Nc2cccc3cnccc23)cc1 +COc1ccc(Br)c(C(=O)N(C)Cc2cnn(C)c2)c1 +CCOC(=O)c1c[nH]nc1S(=O)(=O)N1CCCC(C)C1 +Oc1cc(-c2cccnc2)cc2c1OCCN(Cc1nccs1)C2 +Cc1occc1C(=O)N1CCN2CC(OCc3ccccn3)CC2C1 +CC(=O)Nc1cc(NC(=O)N2CCc3cc(F)ccc3C2)ccc1C +CCC(C)n1ncc(C(=O)NCC2(CC)CC2)c1C1CC1 +Nc1ncnc2c1ncn2CCCSc1ncc2ccccn12 +O=S(=O)(c1ccc(NC2CCC(O)CC2)nc1)N1CCCC1 +CC(NC(=O)c1ccccc1)C(=O)NCC(C)(C)C(N)=O +Cc1n[nH]c(SCC(=O)N(Cc2ccccn2)Cc2ccco2)n1 +CN(C)c1ccc(C2CCN(C(=O)c3cnccn3)CC2)nc1 +Cc1ccc(C(=O)N2CCC(C(=O)N3CCCCC3)CC2)c(C)c1 +Cc1cc(C)n2nc(C(=O)NCCCN(C)S(C)(=O)=O)nc2n1 +O=C(NCc1ccc2c(c1)OCO2)N(Cc1ccco1)C1CC1 +NC(=O)c1cc(Cl)ccc1NCC(=O)Nc1cccc(F)c1 +Cc1csc2nc(CNc3ccccc3F)cc(=O)n12 +Cn1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)cc2occc21 +Cc1cc(C)cc(OC(C)C(=O)Nc2ccc(C(N)=O)cc2)c1 +Cc1ccc(-c2csc(NC(=O)c3snnc3C)n2)cc1 +Cc1cc(NCCNc2ncccn2)n2c(nc3ccccc32)c1C#N +CCN(CC)C(=O)N1CCC(C(=O)Nc2ccc(C#N)cc2)CC1 +COc1ccc(CC(=O)c2ccc(OC)c(OC)c2C)cc1OC +COc1cccc(CCNS(=O)(=O)c2ccccc2)c1 +CC(=O)Nc1cc(NCc2cccc(C)c2)ccc1F +CC(C)NC(=O)CN(C)C(=O)c1ccccc1Cl +CC(C)C(NC(=O)c1cnccn1)c1ccc2c(c1)OCCCO2 +C=CCN(CC(F)(F)F)C(=O)c1[nH]c(C)c(C(=O)OC)c1C +CCc1cc(C2CCCN2C(=O)c2ccnn2C)on1 +O=C(NCC(=O)N1CCCC1)c1cccc(CN2CCCC2=O)c1 +Cc1c(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)cnn1C +O=C(NCCCN1CCCC1=O)c1ccc(NC(=O)C2CC2)cc1 +CCc1csc(C2CCCN(C(=O)CCn3ccnn3)C2)n1 +CNC(=O)CC1CCN(C(=O)c2scnc2C2CC2)CC1 +CC(C)CC1COCCN1C(=O)CCNC(=O)Cc1ccccc1 +Cc1cnn(C2CN(Cc3csc(COc4ccccc4)n3)C2)c1 +COc1ncccc1CNC(=O)C1CCN(c2ccc(C)cc2)C1=O +Cc1noc(CNC(=O)c2ccc(-c3cnco3)cc2)n1 +O=C(CNC(=O)C(c1ccccc1)c1ccccc1)NC1CC1 +COc1ccc2c(c1F)C(c1ccc(N)cc1)NCC2 +COc1ccc(-n2cc(CNC(=O)N3CCOCC3C)nn2)cc1 +CC(NC(=O)c1csc2ccccc12)c1ncon1 +CCCCNC(=O)c1snc(C(=O)NCCC)c1N +CC(C)(C)c1cccc(OC(=O)C2CCCN(C(N)=O)C2)c1 +CCN(CCc1ccncc1)C(=O)c1ccc(N)c(N)c1 +Cc1ccc(-c2ncc(CN3CCNC(=O)C3(C)C)s2)o1 +O=C(C1CCOc2ccccc2C1)N1CCC(N2CCOC2=O)CC1 +CCN(CC(O)c1ccc(C)cc1)C(=O)C(C)(C)NS(C)(=O)=O +Cc1noc(C)c1C(C)NC(=O)CCc1nc(-c2ccco2)no1 +N#Cc1cccc(NC(=O)c2csc(-c3ccsc3)n2)c1 +O=C1CCC(C(=O)NCCOCc2ccc(Cl)cc2Cl)N1 +COc1cccc(NC(=O)NCCNc2ccc(C)nn2)c1 +CCNC(=O)C1CCCN(C(=O)c2c[nH]c3cccc(F)c23)C1 +N#CCn1c(CSc2nncs2)nc2ccccc2c1=O +Cc1nc(C)c(C(=O)N2CCCC(Cc3cccnc3)C2)s1 +COc1cccc(NC(=O)N2CCN3C(=O)NCC3C2)c1 +O=C1CCC(C(=O)NCC2(c3cccc(Cl)c3)CCCC2)CN1 +CCCc1cc(=O)n2c(n1)SCC2CC(=O)NC1CC1 +CCCCS(=O)(=O)NCC(=O)N1CCCC1c1ccco1 +Cc1cc2n(n1)CCCN2C(=O)CCC(=O)NCc1ccccn1 +Cc1nc2ccccc2n(Cc2nncn2C)c1=O +COC(=O)c1cc(CN2CCN(C(=O)OC(C)(C)C)CC2C)c[nH]1 +c1cc(SCc2nc(-c3ccoc3)no2)ccn1 +CCC(Nc1nc(C)nc2c1cnn2C)C(=O)NC +CC(C)(C)OC(=O)N1CCC(COCc2cccnc2)CC1 +CC(C)(C)n1nc(C(=O)Nc2nc[nH]n2)cc1C1CC1 +O=C(Cn1cnnn1)Nc1ccc(C(=O)NCc2ccccc2)cc1 +O=C(COC(=O)CCc1ccsc1)Nc1cccc2ncccc12 +Cc1cc(-c2nnc(CN(C)c3cccc(C#N)c3)o2)c(C)o1 +C=CCN1C(=O)C(C)NC12CCN(C(=O)c1cccc(F)c1)CC2 +C#CCOC(=O)CSc1nnc(-c2ccccc2C)n1CC +Cc1cccc(C(=O)NCc2cnn(Cc3ccccc3)c2)n1 +COC1CCCN(Cc2cnc3ccc(C#N)cn23)C1 +COCCNC(=O)N1CC(c2nc(-c3cccc(Cl)c3)no2)C1 +COc1ccc(-c2nn3cccnc3c2CO)cc1OC +CCc1ccc(C(=O)NC(C)c2ccc(C)o2)cc1 +Cc1cccnc1CN1CCN(C(=O)c2cc(Cl)c[nH]c2=O)CC1 +O=C(Nc1ccc(F)c(F)c1F)N1CC2CC(O)C(O)CC2C1 +Clc1ccc(NCc2nnc(-c3ccccc3)o2)cc1 +Cc1cccc(NCC(=O)N2CCc3ccccc32)c1 +COc1nccnc1NC1CCN(C(=O)c2ccc(C)cc2)CC1 +CC1COCCN1C(=O)CNC(=O)NCc1ccccc1 +CC(C)c1ncc(Cl)c(C(=O)NCCc2ccco2)n1 +CCc1ccccc1OCC(=O)N1CCCN(C(N)=O)CC1 +COc1cccc(-c2nnc(SCC(=O)Nn3cnnc3)o2)c1 +O=C(C1Cc2ccccc2S1)N1CCN(CCn2cncn2)CC1 +O=C(NCC1(O)CCc2ccccc2C1)c1ccc(F)cc1F +CCCc1noc(C2CCN(C(=O)CCC3CCCC3)CC2)n1 +CC(C)(C)NC(=O)CNc1cccc(C(=O)NCC2CCCO2)c1 +CC=CC1NCCc2c1cc(OC)c(OC)c2Cl +OC(CNCc1cccc2c1OCCCO2)c1cccc(F)c1 +CCCCNC(=O)NCCc1coc(-c2ccccc2)n1 +COc1ccc(Cl)c2c1N(C(=O)CCN1CCOC1=O)CCC2 +c1ccc(SCc2nc(-c3ccccn3)no2)cc1 +c1ccn2c(Sc3ncnc4sccc34)ncc2c1 +Cc1ccc(C(=O)COC(=O)C2CC(=O)N(c3ccccc3)C2)cc1 +CC1CCN(C(=O)c2cnc3c(cnn3Cc3ccccc3)c2)CC1 +CC(C)(C)C(=O)N1CCN(C(=O)Nc2ccncc2F)CC1 +CC(Nc1cc(N2CCCC2CO)ncn1)c1ccc(C#N)cc1 +CC(C)C(NC(=O)c1ccco1)C(=O)N=c1[nH]cn[nH]1 +CCc1ccc(NC(=O)CC(NC(N)=O)c2ccccc2)cc1 +Cc1ccc(C(=O)N2CCN(CCCNS(C)(=O)=O)CC2)s1 +CC(=O)Nc1ccc(-c2nc3cc(C)cc(C)c3o2)c(O)c1 +CC(=O)c1cnc(NC(=O)c2cccc(OCC(F)F)n2)s1 +O=S(=O)(c1ccccc1)n1ccc2cc(-c3cn[nH]c3)cnc21 +CCc1ccc(-c2ccc(N)c(=O)n2C2CC2)cc1 +COC(=O)Cn1c(=NC(C)=O)sc2cc(F)cc(F)c21 +O=C(Cc1cccs1)N1CC2OCCN(CC3CCCO3)C2C1 +COC(=O)c1cccc(NC(=O)c2nccc3cc(N)ccc23)c1 +CCCS(=O)(=O)NCC1(Sc2ccccc2)CCOCC1 +CC(=O)NCCCS(=O)(=O)c1ccc(C(C)C)cc1 +Cc1ccc(C(=O)N2CCC3(CC2)CNC(=O)c2ccccc2O3)o1 +Cc1ccc(N2CCCC2=O)c(C(=O)NCCc2cccs2)c1 +CC(NC1=NS(=O)(=O)c2ccccc21)c1nc(C(C)(C)C)no1 +CCOc1ccc(CC(=O)NCCc2csc(C)n2)cc1 +COc1ccc(NC(=O)N2CCN(c3ncccn3)CC2)cn1 +CCCn1cc(-c2ccncc2)cc1C(=O)NC1CCCC1 +Nc1nc(Cn2c(=O)oc3ccccc32)nc(N2CCCCC2)n1 +CC(=O)N1CCC(C(=O)Nc2cccc(NC(=O)C3CC3)c2)CC1 +CCc1c(C)cc(-c2nc(C3CCOC3)no2)c(=O)n1C +COc1ccccc1CNC(=O)Cn1nc(C)ccc1=O +O=C(Cc1ccsc1)N1CCCC(OCc2nc(C3CC3)no2)C1 +CCOC(=O)C1N=C(COC(C)=O)C(CC)=C1C +CN(C)S(=O)(=O)NC1CCCc2cc(OC(F)F)ccc21 +COc1ccc(C(=O)NCC(CC(C)C)N2CCOCC2)cc1 +O=C(NCc1nnnn1C1CCCCC1)c1ccccc1 +CC(C)N(CCO)C(=O)CN1CCN(c2ccc(F)cc2)C1=O +Cc1ccc(NC(=O)Cn2nc(-c3cccs3)oc2=O)cc1Cl +CCOc1ccc2cc(C(=O)N3CCCC(O)C3)[nH]c2c1 +Cc1cc(C)n(CCNC(=O)c2cc3ccc(Cl)cc3n2C)n1 +Cc1cccc(C)c1-n1nnnc1CN(C)CCc1ccncc1 +COc1cc(C)ccc1OCC(=O)NCc1ccco1 +Cc1c(-c2nnc(NC(C)C)s2)cnn1-c1ccccc1 +Cc1nc(N)cc(N2CCCC(Cc3nc4ccccc4[nH]3)C2)n1 +CCN(C(=O)COC(=O)c1[nH]nc2ccccc12)c1ccccc1 +CC(C)C1C(=O)NCCN1S(=O)(=O)N1CCCC1c1ccco1 +O=C(c1ccnc2c1OCO2)N1CCCN(C(=O)C2CCC2)CC1 +CC(C)OCCC(=O)Nc1cccc(N2CCCS2(=O)=O)c1 +Cc1ccccc1CCNC(=O)CS(=O)(=O)c1nccn1C +CCn1cc(C(=O)NCc2ccc(CN3CCCC3=O)cc2)cn1 +O=C(NCc1cccc(CN2CCOCC2)c1)C1CCCO1 +Cc1ccc2c(c1)C(=O)NC1(CCN(C(=O)C3CCCC3)CC1)N2 +Cc1ccc2c(c1)nc1n2C(CNC(=O)Cc2ccccc2)COC1 +Cc1ccc2ncc(C(=O)NCc3ccccc3Cn3cccn3)n2c1 +CCCCN1CC(C(=O)NCC2CCCO2)CC1=O +COc1cccc(C(=O)N(C)c2ccccc2)c1O +Cc1cnn(CC2CN(c3cc(C)nc4ncnn34)CCO2)c1 +CCC(C)(C)NC(=O)Cn1c(C)c(C)sc1=O +Cc1cc(C(=O)N2CCN(c3ccccc3F)CC2)c(C)o1 +CC(C)c1ccc(OCC(=O)Nc2ccccc2C(N)=O)cc1 +Cc1cc(C(=O)Nc2cc(-c3ccccc3Br)n[nH]2)on1 +Cc1nc(CC(=O)N(C)CC2CCN(c3ccccc3)C2)cs1 +C#CCNC(=O)c1nccnc1-c1nc2ccccc2s1 +COC(=O)c1cc(S(=O)(=O)Nc2cc(Cl)ccc2C)c[nH]1 +COc1cccc2c(=O)cc(-c3ccc4c(c3)OCO4)n(C)c12 +NC(=O)C1CCC(NC(=O)Nc2cccc(N3CCOC3=O)c2)CC1 +CC(CC#N)N(C)C(=O)Nc1ccc2c(c1)OCO2 +Cc1nn(C)c(C)c1C1CCCN1C(=O)CC1C=CCC1 +Cc1nn(-c2ccccc2)c2sc(C(=O)NCCCO)cc12 +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)NCCCO +O=c1ccc2cc(S(=O)(=O)N3CCOCC3)ccc2[nH]1 +Cc1nn(C)c2ncc(NC(=O)N(Cc3cccnc3)C(C)C)cc12 +CCCc1nnc(NC(=O)CCCc2ccc3[nH]c(=O)[nH]c3c2)s1 +NC(=O)c1cn[nH]c1NC(=O)C1CC12CCCc1ccccc12 +Cc1ccccc1OCCNC(=O)NCC(F)(F)F +Cc1ccc2c(c1)nc(CO)n2CCN1CCOCC1 +COc1c(C)cc(CN(C)C(=O)C2CCN(C(C)=O)CC2)cc1C +Cc1nc(C2CCCCCN2C(=O)Nc2ccncc2)no1 +NC(=O)c1cnc(NCCC(=O)NC2CCCC2)c(Cl)c1 +COCc1ccc(C2CCCN2C(=O)NCc2ccnn2C)o1 +CC(C)Nc1nn(-c2ccccc2)c(=O)n1C(C)C +CC1=NC(C(=O)N2CCCC(C(=O)NC(C)C)C2)C(C)=C1C +CC1CCC(NC(=O)CSc2nncn2C(C)C)CC1 +Cn1ccc(NC(=O)NCC2(c3ccccc3)CCCC2)n1 +CCn1ccc2ccc(NC(=O)N(C)Cc3noc(C)n3)cc21 +Cc1ccc(C(=O)N2CCN(C3CCOC3=O)CC2)s1 +O=C(CSc1nnc2[nH]c3ccccc3n12)c1ccccc1 +CC(=O)NC1CCOc2c(C)cc(C(O)CC(C)C)cc21 +Cc1nnc(C)n1NC(=O)N1c2ccccc2Sc2ccccc21 +Cc1ccc(C(=O)N2CCCC2c2ccc3c(c2)OCCO3)cc1C +CNC(=O)c1ccc(CNCC2(c3ccc(F)cc3)CC2)cc1 +CC(=O)c1ccc(NC(=O)NC2CC2c2ccccc2)cc1C +COc1ccc(OC)c(C(O)CNc2ncccc2F)c1 +CC(C)OC(=O)Cn1cnc2ccc(Cl)cc2c1=O +CCOC(=O)c1c(C)nc(N)nc1COc1cccc(CC)c1 +CCCN(CCC)C(=O)c1c(NC(C)=O)sc2c1CCCCC2 +Cc1nc2cc(C(=O)Nc3ccc(-c4nc[nH]n4)cc3)ccc2n1C +CC(=O)NCC(=O)Nc1ccc(Oc2cccnc2)c(C)c1 +O=C(Nc1sccc1C(=O)NCC1CCCO1)c1cccs1 +CCCNc1nc2ccc(S(=O)(=O)C(C)C)cc2s1 +Cc1nc(-c2ccccc2)ccc1C(=O)NCc1cncnc1N +CCNC(=O)Nc1nc2c(s1)CN(S(=O)(=O)CC)CC2 +CCNc1ncc(CN2CCCn3nc(C(=O)OC)cc3C2)cn1 +Cc1sc(=O)n(Cc2nc(-c3ccc(C#N)cn3)no2)c1C +Cc1nc2ccc(NC(=O)C(C)NC(=O)c3ccco3)cc2s1 +Cc1cc(C)n(CC(C)Cn2c(=O)[nH]c3ccccc3c2=O)n1 +c1ccc(OCCc2nc3cc4c(cc3[nH]2)OCCO4)cc1 +OC1CCCN(c2ncnc3scc(-c4ccccc4)c23)C1 +CCN1CCC(=O)c2cc(Br)ccc21 +CC(C)Cn1cc(NCc2c[nH]nc2-c2cccnc2)cn1 +O=C(NCCCc1ccco1)c1ccc(-c2ccccc2)[nH]c1=O +Cc1noc2ncc(C(=O)NCCNC(=O)C(C)C)cc12 +CC1CC1CNC(=O)NCc1noc(-c2ccsc2)n1 +CN(C)C(=O)CNC(=O)NCc1cc(=O)[nH]c2ccccc12 +COc1cc(NCC2COc3ccccc3O2)nc(C)n1 +OCc1cccc(-c2cc(NCc3ccccn3)nc3[nH]ccc23)c1 +O=C(NCCCN1CCc2ccccc21)c1ccccc1 +CCc1c(C(=O)N2CCN(C(C)COC)CC2)[nH]c(C)c1C(C)=O +Cc1ccc(C)c(C(=O)Nc2cc(-c3cccnc3)no2)c1 +C#CCN(Cc1ccco1)C(=O)CSc1nccn1C +O=C(NCCc1ccccn1)NCCc1cccc2ccccc12 +Nc1ccc2ccnc(C(=O)Nc3ccccc3)c2c1 +COc1ccc2c(CC(=O)N=c3sccn3C)coc2c1 +C#CCOc1ccc(C(=O)NC(C)C(O)c2ccc(OC)cc2)cc1 +COc1ccc2c(c1)C(O)(CC(=O)c1ccc(C)cc1C)C(=O)N2 +CC(C)CNc1nc(C(=O)Nc2ccccn2)cs1 +Cc1ccc(-c2nnc(NC(=O)C3CC3)s2)cc1 +O=C(CNC(=O)c1ccccn1)NCc1ccco1 +Cc1ncc(CNC(=O)Cc2ccc(F)c(Br)c2)s1 +CCCOc1cc(C)ccc1NC(=O)c1cc[nH]n1 +CN(Cc1ccc(F)cc1F)C(=O)c1cccn1Cc1cccnc1 +CC(NC(=O)CCn1cnc2ccccc2c1=O)C(N)=O +CCc1cc(C(O)CC(C)C)c2c(c1)C(CC)C(=O)N2 +CC(C)CC1NC(=O)C(CC(C)C)N(CO)C1=O +Cc1ccc(NC(=O)CCSc2nn3cnnc3o2)cc1 +COCCCNc1ncnc(Nc2cc(C)cc(C)c2)c1N +O=C(Cn1ncc(=O)c2ccccc21)Nc1ccccc1Cl +Cc1ccnn1CC(=O)NC1CCCc2nc(-c3cccnc3)ncc21 +Cc1ccn(C(C)CC(=O)Nc2ccc(Br)c(C)c2)n1 +Cc1nn(-c2ccccc2)c(C)c1Br +CC(=O)N1CCc2cc(S(=O)(=O)NC(C)(C)C)ccc21 +CCN(CCO)C(=O)c1cc(Br)cnc1NC +C#CCOc1cc(F)ccc1NC(=O)Cc1ccccc1O +CCn1cc(NC(=O)c2ccc(Oc3ccc(C#N)cn3)cc2)cn1 +CC1CCCC(CO)(NC(=O)c2cc(Cl)cn2C)C1 +C=CCn1c(CNC(=O)C2CCCCC2)nnc1SC +CC(=O)NC12CC3CC(CC(Br)(C3)C1)C2 +CC(NC(=O)NCCNc1ncc(Cl)cc1Cl)C1CCCO1 +CCc1nnc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)s1 +Cc1nnsc1C(=O)NC(C)Cc1ccco1 +COC(=O)c1c(C)cccc1NS(=O)(=O)c1ccc(C(C)=O)cc1 +CC(C)=CC1C(C(=O)NC2(C(N)=O)CCCCC2)C1(C)C +CCc1c2c(nc3cc(C(=O)OC)n(C)c13)CCCC2=O +COc1cccc(NC(=O)CSc2nnc3nc(C)cc(C)n23)c1 +Cc1nn(C)cc1C(C)NC(=O)C(C)Oc1ccc(F)cc1Cl +CC1(C(=O)Nc2nc3ccccc3[nH]2)Sc2ccccc2NC1=O +COC(=O)C(C)n1ccnc1Cc1ccc(F)cc1 +CCCCNc1ccccc1C(=O)NCc1ncn(C)n1 +CCc1cc(C(=O)NC(C)C)nc2cc(-c3ccco3)nn12 +Cc1cc(C(=O)Nc2nc(-c3ccncc3)cs2)n(C)n1 +CCc1ccc(CNC(=O)NCc2ccc(C(=O)N(C)C)cc2)s1 +Nc1ccc(C(=O)N2CCc3sccc3C2)c(Cl)c1 +Cc1ccc(OCc2nc(-c3ccc(F)cc3)no2)nc1 +CC(CNC(=O)c1ccnnc1)c1nc(-c2ccccc2)no1 +c1cn2ccc(-c3nc(C4CCOC4)no3)cc2n1 +CNC(=O)c1cc(Oc2ccc(NC)cc2)ccn1 +CCCC1CN(C(=O)NCc2cc(=O)[nH]c3ccccc23)CCO1 +O=C1COc2cc(C(=O)Nc3ccc(Cl)c(Cl)c3)ccc2N1 +CCn1ncc(-c2cc(C(F)F)n3ncc(C(=O)OC)c3n2)c1C +Cc1ccc2nc3nc4ccccc4n3c(=O)n2c1 +O=C(Cc1cccc(F)c1F)NCc1ccc(OCC2CC2)nc1 +CNC(=O)CCc1cc(C)nc(C2CCCN(c3cnccn3)C2)n1 +Cc1nsc(N2CCN(Cc3nc4c(s3)CC(C)CC4)CC2)n1 +OCCCCSc1ncnc2c1cnn2-c1ccccc1 +Cc1sc2nc(COC(=O)c3ccc(O)cc3)nc(N)c2c1C +CC(C)c1nnnn1CC(=O)NC(C)c1ccccc1 +CN(Cc1ccccc1)C(=O)Cn1cc(-c2ccc(F)cc2)oc1=O +COc1ccccc1CCNC(=O)c1cccc(NC(N)=O)c1 +Cc1cccc(NC(=O)NCC2CCOC2C(C)(C)C)n1 +COCCCCNC(=O)c1c(F)cccc1OC +CC1CCN(C(=O)CNc2ccccc2OCC2CCCO2)CC1 +O=C(Nc1cccc(Cn2cccn2)c1)c1cc2ccccc2c(=O)[nH]1 +CC(C)OC(=O)CCNC(=O)c1ccc(F)nc1 +CN(CC(N)=O)C(=O)CCn1c(=O)oc2cc(Cl)ccc21 +O=C(NCC1CN2CCCCC2CO1)c1cc(F)c(F)c(F)c1 +CCN(CC(=O)NC(C)(C)C)C(=O)C1CCN(C(C)=O)CC1 +CCOc1ccccc1OCC(=O)c1ccc(O)cc1O +NC(=O)CC1CCCN(C(=O)Nc2cnn(-c3ccccc3)c2)C1 +COCCN1C(=O)C2(CCN(C(=O)N(C)C)CC2)c2ccccc21 +CC(C)Oc1ccc(C2CC(=O)Nc3cc4c(cc32)OCO4)cc1 +COC(=O)N1CCC(NC(=O)Nc2cccc(C)c2)CC1 +C=CCN1C(=O)COC2CN(C(=O)c3ccccn3)CC21 +Cc1cc(O)cc(C)c1CNc1cnccc1Cl +CC(C)C(C)N(C(=O)c1cnn2c(-c3ccccc3)ccnc12)C1CC1 +CC(=Cc1ccco1)C1CC(=O)Nc2n[nH]c(-c3ccccc3)c21 +Cc1cccc(C)c1NC(=O)c1coc(NC(=O)c2ccco2)n1 +CC(C)c1csc(CN2CCN(CCn3cncn3)CC2)n1 +Cc1ccc(CN2CCN(C(=O)c3ccc(Cl)cc3F)CC2)o1 +CCOC(=O)c1ccc(N2CCCN(C(=O)C3CC=CC3)CC2)nc1 +Cc1cccc(CNC(=O)NCCCc2cn[nH]c2C)n1 +COCc1nc(C(=O)NC(C)c2cccc(-n3cccn3)c2)cs1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)Nc1nccs1 +Cn1nc(CNC(=O)c2cc(-c3ccco3)n[nH]2)c2ccccc2c1=O +CSc1c(C#N)c(N)nc(SCC(N)=O)c1C#N +CC(C)NC(=O)C1CC1c1ccc2c(c1)OCCO2 +O=S(=O)(c1ccc(F)cc1F)N1CCN2CCCC2C1 +CN1CCc2cc(C(=O)Nc3ccccc3)ccc21 +Cn1ccnc1COc1ccc(NS(=O)(=O)c2ccccc2)cc1 +Cc1ccccc1C(=O)NCC(=O)Nc1ccc(F)cc1 +CCCn1nc(-c2ccccc2OC)cc1C(=O)NC(C)C +c1ccn2cc(CSc3nnc(-c4ccncc4)o3)nc2c1 +C=CCNC(=O)CN(c1cc(Cl)cc(Cl)c1)S(C)(=O)=O +N#CCc1nc2cc(C(F)(F)F)ccc2n1CC#N +CS(=O)(=O)Nc1ccc(NC(=O)CCc2ccco2)cc1Cl +CCCS(=O)(=O)N1CCC(C(=O)NCC(=O)OC)CC1 +CN(C)C(=O)CN(C)C(=O)COc1ccc(C(C)(C)C)cc1 +CS(=O)(=O)N(Cc1ccc(F)cc1F)c1ccc(F)cc1 +COc1ccc(NC(=O)CCOCC(C)C)c(Cl)c1 +CC(OC(=O)c1cccc(=O)n1C)c1nc2cc(Cl)ccc2n1C +COc1ncccc1NC(=O)N(C)CC(=O)Nc1ccccc1 +CC1Sc2ccc(C(=O)N3CCCCCC3)cc2NC1=O +Cc1nc(C)c(CNC2CCN(c3ccc(F)cc3F)C2)s1 +CC(Nc1ccc(OCC(F)(F)F)nc1)C(=O)N1CCOCC1 +CCN(CC)C(=O)CCC(O)c1cccc(N)c1 +CC(C)CN(C(=O)CN1CC(C)OC(c2ccccc2)C1)C1CC1 +CC(C)=CC(=O)OCc1nnc(-c2cccc(C)c2)o1 +CCc1nn(CC(=O)N2CCOCC2)c(=O)c2cc3occc3n12 +Cc1cc(C)n(Cc2nc(-c3ccsc3)no2)n1 +CC(=O)c1c[nH]c(C(=O)Nc2ccc(-n3cnc4ccccc43)cc2)c1 +CCc1ccc(C(=O)CCC(=O)N(C)C(C)c2ccco2)cc1 +O=C(c1cccs1)N(CCc1cccs1)C1CC1 +CC(=O)c1cccc2nc(-c3cccc(N)c3)oc12 +Cc1ccn2c(=NC(=O)c3ccc(-n4cc(C)cn4)cc3)[nH]nc2c1 +CC(C)(C)C(=O)CSc1nnnn1C1CCCCC1 +COc1ccc2nnc(CCC(=O)NC3CCCCC3)n2n1 +COc1ccc(OC)c(-c2csc(NC(=O)Cn3ccnc3)n2)c1 +COc1ccc(S(=O)(=O)N(C)C2CCCCC2O)cc1OC +O=C(NCc1ccnc(OCC2CC2)c1)c1cc(F)ccc1F +CC(=O)c1cccc(NC(=O)N(C)C(C)C(C)C)c1 +CCOC(=O)c1nc(C(=O)Nc2cccc(C#N)c2)oc1C +CC(C)c1noc(CCNC(=O)CCn2c(=O)oc3ccccc32)n1 +COc1ccc(CC(=O)NCCNc2cccc(F)c2C#N)cc1F +CC1=Nc2ccccc2Nc2c1c(=O)[nH]c1ccccc21 +C=CCOc1cccc(NC(=O)c2cc3c([nH]c2=O)CCCC3=O)c1 +Cn1cc(-c2cn3cccc(N)c3n2)c2ccccc21 +CC(C)Oc1ccccc1NC(=O)NCc1cccs1 +CCC(C)C(NC(=O)Cn1cccn1)c1nc2ccccc2[nH]1 +CC(=O)NCCNC(=O)NCCc1cc(Cl)cc(Cl)c1 +Cc1noc(C)c1CN(C)C(=O)c1occc1CN1CCOCC1 +Cc1cccnc1NC(=O)c1ccc2c(ccn2C)c1 +O=C(Nn1nnc2ccccc2c1=O)c1ccccc1 +COCc1c(C(=O)Nc2nc(C)cs2)sc2cccc(F)c12 +O=C(CCS(=O)(=O)c1ccccc1)NCc1cccnc1 +CC(C)N(C(=O)CCCNC(=O)c1ccc(F)cc1)c1ccccc1 +CSc1cccc(NC(=O)CCC(=O)c2ccc(F)cc2)c1 +CCOc1ccccc1NC(=O)c1cc(-c2cccs2)[nH]n1 +Cc1nc(C(Cc2ccsc2)NC(=O)C2CCCO2)sc1C +O=c1c2ccccc2cnn1Cc1cccc(F)c1 +CC(C)C(=O)Nc1cccc(NC(=O)Cc2cccc(F)c2F)c1 +CCN(C(=O)C1CCOCC1)c1ccc(F)cc1 +CCCCc1ccc(NC(=O)c2nccnc2N)cc1 +CCC(NC(=O)C1CC(=O)N(C)C1)c1ccc(OC)cc1 +Cc1ccc(C(=O)Nc2nccn(C)c2=O)c(Br)c1 +CCCN1CCCn2c1nc1c2c(=O)[nH]c(=O)n1C +CC(OCC1CCCCO1)C(=O)N1CCCC1c1ccccc1 +Cc1ccc(NC(=O)c2nccc3c(N)cc(C)cc23)cc1 +Cc1cc(NC(=O)c2cccc(F)c2F)nn1C +Cc1ccoc1CN1CCOC(C)(c2ccccc2)C1 +COCCNC(=O)CC1CCCN(C(=O)c2cccc(F)c2)C1 +Cc1nc(CN2CCC3(CCCO3)CCC2=O)no1 +CNC(=O)C1CN(C(=O)c2cc(C)cc(C)c2)CC12CCCC2 +Clc1cccnc1NCc1cnn2ccccc12 +N#Cc1ccccc1Oc1ccc(NC(=O)CNC(N)=O)cc1 +CC(=O)c1ccc(Nc2ncnc3n[nH]cc23)cc1 +O=C(Nc1ccc(Cl)c(F)c1)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +N#Cc1ccc(NC(=O)c2cccc(Br)c2)cc1 +O=C(Nn1cnc2ccccc21)c1ccc2ncsc2c1 +CN(C)C(=O)c1ccccc1NCCOc1ccccc1F +N#CCCN(Cc1cccc2cn[nH]c12)CC1CC1 +COC(=O)c1cccc(NC(=O)COc2ccc(C)cc2)c1C +Cc1ccc(C(C)NC(=O)CCC2CCCO2)cc1F +CCOC(=O)c1sc(NCC2CCCC2)nc1C +CC(NC(=O)C1CCOCC1)C(=O)NC(C)(C)CC(C)(C)C +CC(NC(=O)c1cn(CC(=O)N(C)C)nn1)c1nc2ccccc2[nH]1 +CS(=O)(=O)N(CC(=O)Nc1ccccc1)C1CCCCC1 +CC(C)CNC(=O)C(C)Nc1ccc(C(=O)NC2CC2)cc1 +CCOc1cc(CNCCc2nccs2)ccc1O +CCC(C)NC(=O)NC(CC(=O)OC)c1ccc(C)cc1 +COc1ccc(C(O)CNc2ccc(C)cc2)cc1C +COc1ccc(-c2[nH]c3ccc(F)cc3c2C#N)cc1 +Cc1cnc(-c2cccc(NC(=O)C(C)c3ccsc3)c2)o1 +CC(OC(=O)c1ncn(-c2ccccc2)n1)C(C)(C)C#N +COC(=O)CCC1CCCCN1c1nc2c(s1)c(C)nn2C +CS(=O)(=O)c1ccccc1C(=O)Nc1ccccc1OC(F)F +Cc1ccc(Cn2nccc2NC(=O)Cc2ccc(F)cc2F)o1 +COc1ccc(C(=O)CCC(=O)NC2CCCC2)cc1 +COc1cccc(CN2C(=O)OCC2C(=O)NCc2cccnc2)c1 +COc1cccc(N2C(=O)c3ccccc3NC2c2ccccn2)c1 +CCN(CC)C(=O)N1CCN(C(=O)c2nccnc2N)CC1 +CC(C)(C)OC(=O)N1CCC(C(=O)N2CCc3[nH]ncc3C2)C1 +O=C(NCC1(O)CCc2ccccc2C1)c1c(F)cccc1F +NC(=O)c1ccc(NC(=O)CCCC(=O)c2ccc(F)cc2)cc1 +CC(C)c1ncc(C(=O)NCC2CCCO2)c(N)n1 +CN(C)C(=O)C1CCN(C(=O)NCC2(c3ccccc3)CCC2)CC1 +COc1cccc(-c2cc(COC(=O)c3cccn(C)c3=O)no2)c1 +CCN(CC)C(=O)NCCc1ccn(-c2ccccc2)n1 +O=C(NCC1CCc2ccccc2N1)c1nc2ccccc2c(=O)[nH]1 +NC(=O)c1cc(Cl)ccc1OCC(=O)c1ccc(F)cc1 +COC1CCC(CC(=O)Nc2nc(-c3cccc(O)c3)cs2)CC1 +N#Cc1nnn(-c2cccc(F)c2)c1-c1cccc(F)c1 +O=C(NCCc1ncc2ccccn12)Nc1ccccc1 +O=C(NCc1ccc2c(c1)CCC2)c1ccc(F)nc1 +CCC(C)(C)NC(=O)c1ccc(CSc2ncn[nH]2)cc1 +CC(=O)Nc1ccc(OCC(O)COc2cc(C)ccc2C)cc1 +O=C(NCCc1ccco1)NCc1cccc(NC(=O)C2CC2)c1 +COc1cc(NC(=O)c2onc(C)c2Cl)c(OC)cc1Cl +O=C(Nc1cccnc1)c1cc(-c2ccc(F)cc2)[nH]n1 +Cc1ccnc(NC(=O)c2cc(-c3ccco3)nc3onc(C)c23)c1 +O=C(Nc1ccc(SC(F)F)cc1)c1[nH]ncc1Br +CC(=O)N(CCC(=O)NCc1nccs1)Cc1ccccc1 +Cc1c(C(=O)Nc2cccc(F)c2)nc2ccc(Cl)cn12 +CC(NC(=O)N(C)CCC(F)(F)F)c1ccncc1 +CC(CNC(=O)C(C)S(=O)(=O)c1ccccn1)c1ccccc1 +COCCNC(=O)c1cnn(-c2ccccc2C)c1C1CC1 +O=C1OCCC1Sc1nnc(-c2cccc3ccccc23)o1 +CC(C)CC1COCCN1Cc1cnc2ncccn12 +CCC(=O)N1CCCCC1C(=O)Nc1cc(F)ccc1OC +CCC(=O)OCC(=O)c1ccc2c(c1)OCCO2 +CCC(NC(=O)c1ccc(N(C)C)cc1)c1ccc(C)cc1 +CC(=O)c1ccc(OS(=O)(=O)c2ccc(F)c(C#N)c2)cc1 +C#CCNC(=O)CSc1nc2ccccc2c(=O)n1CC=C +O=C(CSc1ccc(-c2ccccc2)nn1)N1CCCCC1 +CCc1c(C#N)nnn1-c1nc(-c2ccc(F)cc2)cs1 +CC(C)(C)c1oc(C(N)=O)cc1Cn1ncc2ccccc2c1=O +CN(CC12CC3CC(CC(C3)C1)C2)C(=O)Nc1nncs1 +O=C(NC1CCCCC1)C1CCCN1C(=O)C1CC1 +CCn1cc(C(=O)N2CCCC2C(=O)Nc2ccc(OC)cc2)cn1 +N#Cc1ncnc(C(F)(F)F)c1Cc1nccs1 +COC(C)C(=O)NC1CCCc2c1cnn2Cc1ccccc1 +C=CCn1c(=O)n(CC=C)c(=O)n(CC(C)C(C)=O)c1=O +O=C(c1ccc(COCC(F)(F)F)cc1)N1CCCCCC1 +CC(C)(C)C(=O)NCCc1csc(-n2cccn2)n1 +Brc1cccc2c1cnn2-c1cncnc1 +O=C1CC(Cc2ccccc2)CN1Cc1nnc(-c2ccco2)o1 +CN(C)c1ccc(C(=O)Nc2nc(-c3ccccc3F)n[nH]2)cc1 +Cc1cc(NC(=O)CN(C)C(=O)COc2ccccc2)no1 +Cc1nc(S(=O)(=O)C(C)c2ccccc2)n(CC(C)C)c1C +CCN(CC1CC1)C(=O)NCc1ccnc(-n2cccn2)c1 +CCCCCNC(=O)C1CCN(C(=O)Nc2cnccc2C)CC1 +O=C(c1cc(=O)[nH]c2ccccc12)N1CC2CCCC2(CO)C1 +CCC(=O)Nc1ccc(OC)c(S(N)(=O)=O)c1 +O=C(NCc1ccc(F)cc1)c1ccc(-n2cccn2)cc1 +Cc1ccc(NC(=O)Cc2csc(C)n2)c(Cl)c1 +Cc1noc(C2CCCN(C(=O)c3cc(Cl)ccc3Cl)C2)n1 +COc1ccccc1CNC(=O)c1ccccc1-n1nnnc1C +CCOCc1ccccc1NCC(=O)Nc1cccc(C#N)c1 +CCSc1cc(C(=O)Nc2ccc(C)cc2F)ccn1 +COc1ccc(F)cc1NC(=O)NCC1Cc2ccccc2O1 +Cc1c(Cl)cccc1NCC(=O)c1c(N)n(C)c(=O)n(C)c1=O +Cc1cc(C)cc(OCCC(=O)OCc2ccccn2)c1 +O=C(Nc1cnn(CC2CCCO2)c1)c1cc(Cl)ccc1O +COc1cc(Br)c(NC(=O)c2cc(C)on2)cc1OC +O=C(Cc1ccc(F)cc1)Nc1cccc(Cl)c1-n1cncn1 +CN(C)c1ccc(C(=O)NCC(F)(F)F)cc1F +Cc1cc(F)ccc1NC(=O)Cn1ncc2ccccc2c1=O +C=CCNC(=O)NC1CCCN(S(C)(=O)=O)C1 +N#Cc1ccnc(SCC(=O)NCCOc2cccc(F)c2)c1 +O=C(COc1ccc2ccccc2c1)NCC(F)(F)F +CCc1cc2c(N3CCCC(c4noc(C)n4)C3)ncnc2s1 +Cc1cccc(NC(=O)NCCn2ncccc2=O)c1C +C#CCN(CC(=O)NCC(=O)N1CCCC1)C1CCc2ccccc21 +NS(=O)(=O)c1ccc(CNC(=O)C2CCCCCC2)cc1 +N#Cc1ccc(-c2noc(-c3csc(-c4ccc(F)cc4)n3)n2)nc1 +O=C(c1cc(-c2ccccc2Cl)[nH]n1)N1CCCC(O)C1 +CN(Cc1ccccc1Cl)C(=O)CCNC(=O)c1ccsc1 +CCN(CC(=O)NC)S(=O)(=O)c1cc(F)ccc1F +Cc1ccc(C(=O)NCCNc2ccc(-n3cccn3)nn2)cc1C +CCOCCN(C(C)=O)c1cccc(C(F)(F)F)c1 +NC(=O)c1csc(C(=O)NC2CCCCC2)c1 +CCOc1ccc(C2(CNS(C)(=O)=O)CCOCC2)cc1 +Fc1ccc(CN2CCOC(Cn3cccn3)C2)c2ncccc12 +CCn1c(=O)c2ccccc2n(CC(=O)NC2CCCCC2)c1=O +Brc1ccc(CN2CCOCC2)cc1 +COc1ccc2cc(NC(=O)c3ccccn3)cnc2c1 +CCOc1cc(NC(=O)c2c(C)oc(C)c2C)ccc1OC +CCN(CC)C(=O)c1cnc(N2CCCCC2)c2ccccc12 +CC(C)Oc1ccc(F)cc1-c1cn2c(nc3cc(N)ccc32)[nH]1 +O=C(NCC1CC1)c1nc(-c2cccs2)n(-c2ccccc2)n1 +O=C1CN(c2nc(-c3ccsc3)nc3ccccc23)CCN1 +COC(=O)CNC(=O)C(N)c1ccc(O)c(OC)c1 +Cc1nc2ncccn2c1C(=O)NCc1cnc2c(c1)CCC2 +COc1cc(C(=O)N2CCC(O)CC2)cc(Cl)c1OCC(C)C +Cc1ccc(C(=O)N2Cc3ccccc3OC3(CCOCC3)C2)cn1 +CCN(CCO)C(=O)c1ccc(C(F)(F)F)nc1C +CC(C)Nc1cccc(CNC(=O)CN(C)C(=O)c2ccccc2)c1 +O=C(NC1CCCC1)c1nc(Cn2cnc3ccccc3c2=O)no1 +NC(=O)C1CCN(C(=O)Nc2csc3ccccc23)CC1 +Cn1cc(CCNC(=O)C2(c3cccc(Cl)c3)CC2)cn1 +Cc1ccc(CNS(=O)(=O)c2ccccc2F)s1 +Nc1c(-c2cc(Cl)ccc2O)nc2ccc(F)cn12 +O=C(c1cc2c([nH]c1=O)CCC2)N1CCCC(N2CCNC2=O)C1 +C#CCN1CCN(CC(=O)N(C)C(C)c2ccc(F)cc2)CC1 +CSc1nc2nc(C)c(CC(=O)Nc3ccccc3C)c(C)n2n1 +CCCn1c(=O)[nH]c(=O)c2cc(C(=O)NC(C)C)cnc21 +CC(C)CNC(=O)N1CCN(CC(=O)N2CCCCC2C)CC1 +COc1cccc(NC(=O)Cc2nnc(-c3sccc3C)o2)c1 +CC(C(=O)NCc1cccc(COC2CCOCC2)c1)n1cncn1 +COCc1ccc(NCC2CCN(c3ccc(O)cc3)C2)cc1 +O=S(=O)(CCCn1cccn1)c1ccc(Cl)cc1 +COC(=O)CNC(=O)C12CC3CC(CC(Cl)(C3)C1)C2 +CCc1ccc(S(=O)(=O)N2CCN(c3ncccn3)CC2)cc1 +O=C(NCc1ccc(NC(=O)C2CC2)cc1)c1ccccc1O +O=c1c(CNc2ccccc2)cc2cccc3c2n1CCC3 +Cc1cc(C(=O)NC2CCCN(c3ccccc3)C2=O)c(C)o1 +CCCc1noc(C2CCCN(C(=O)N(C)C)C2)n1 +CCc1ccccc1NC(=O)CS(=O)(=O)c1nnc(C2CC2)n1C +COC(=O)c1ccc(C(=O)NC2CCCC2Cc2ccccc2)cn1 +O=C(NCC1CCCO1)c1cc(-c2cccc(Cl)c2)[nH]n1 +CCN(CC(=O)NC(C)(C)C)c1ccc2nnnn2n1 +COCC(=O)N1CCc2ccc(C(O)C(C)(C)C)cc2C1 +CCN1C(=O)CCC2C1CCN2C(=O)c1cccc(C#N)c1 +Cc1cc(Br)c2oc(C(=O)NC(C)(CO)CO)cc2c1 +COc1ccc(CNC(=O)C2CCCN2C(=O)C2CCCCC2)cc1 +O=C(CCC(=O)c1ccc(F)cc1F)Nc1cc(F)cc(F)c1 +CC1CN(CC(=O)NC(C)c2ccc(F)cc2)CC(C)O1 +COC(=O)c1sccc1OCc1cccc(OC)c1 +CN1CCN(C(=O)c2ccnc(OC3CCC3)c2)c2ccc(F)cc21 +CCCOc1c(N)cc(C(C)O)cc1C(C)(C)C +Cc1c(NC(=O)CCc2ccco2)c(=O)n(-c2ccccc2)n1C +CCNC(=O)CNC(=O)c1nn(-c2ccc(Cl)cc2)c(C)cc1=O +CCC(=O)N1CCC2(CC1)CC(NC(=O)c1ccccn1)CO2 +CCCN(C(=O)CCNC(N)=O)C(C)c1cc2ccccc2o1 +CC(C)c1nc2c(Cl)cc(F)cn2c1C(C)O +COC(=O)C(NC(C)=O)(Nc1ncc(C)s1)C(F)(F)F +O=C(Cn1c(=O)oc2ccccc21)NCc1cccc(Cl)c1 +CN(Cc1ccsc1)C(=O)CC1C(=O)NCCN1Cc1ccoc1 +Cc1ccc(N2CCCC2=O)c(C(=O)Nc2nnc(C3CC3)s2)c1 +COC(=O)C(NC(=O)c1ncoc1C(C)C)c1ccccc1Cl +CCC1CCCN(C(=O)C2CCN(S(C)(=O)=O)CC2)C1 +CC(=O)N1CCC(NC(=O)CCn2cncn2)CC1 +CCN(CC(=O)NC(C)C)C(=O)c1ccc(NC(=O)C2CC2)cc1 +CN(C)C(=O)CSc1n[nH]c(C=Cc2ccccc2)n1 +CCCSc1nc(C(C)(C)C)nc2c1c(=O)n(C)c(=O)n2C +O=C(NCC1COc2ccccc2O1)c1ccc2c(c1)OCO2 +O=C(Nc1ccc2c(c1)OCO2)C1CCC(=O)N1Cc1cccs1 +Cc1noc(C2CCCN2C(=O)NCc2cccc3ccccc23)n1 +Cc1nnc(SCC(=O)N(C)C(C)c2ccccc2)n1N +CCc1ccc(CNC(=O)N(C)Cc2ccoc2C)s1 +COC(=O)C(C)CN(C)Cc1cn[nH]c1-c1cccc(C)c1 +COCC(=O)N1CCCc2ccc(NC(=O)c3cn(C)nn3)cc21 +CCC(C)C(NC(=O)Cc1ccc(O)cc1)C(N)=O +O=C(c1ccc[nH]1)N1CCC2(CC1)COCCN(c1ncccn1)C2 +COc1cccc(-c2c(-c3cn[nH]c3)noc2N)c1 +CC(C)(C)OC(=O)N1CCC(NC(=O)Cc2ccsc2)C1 +CCN(Cc1noc(CC(C)C)n1)C(=O)C1CCCO1 +CCCn1nc(-c2cc(C)c(OC)c(C)c2)cc(CO)c1=O +CCOC(=O)C1=C(C)C(C(=O)COc2cccc(C#N)c2)=NC1C +CC(NC(N)=O)C(=O)N(C)C1CCN(c2ccc(F)cc2)CC1 +CCCN(Cc1ccccc1)C(=O)NC1CCOCC1 +COCC(O)Cn1cnc2c(Cl)cc(Cl)cc2c1=O +Cc1ccc(C)c(S(=O)(=O)N(C)Cc2ccc3c(c2)OCO3)c1 +Cc1ccc(-c2ocnc2C(=O)N(C)CCc2ccccn2)cc1 +CCCC(NC(=O)c1ccc[nH]c1=O)c1ccccc1 +CC(Sc1nnc(CO)n1C1CC1)C(=O)NC1CCCC1 +COCCNC(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +C=CCN(Cc1cccs1)S(=O)(=O)Cc1ccccc1 +CCCC1(CO)CCCN(C(=O)c2cc(C)n(CC)n2)C1 +O=C1NCCCCC1n1ccnc1-c1ccccc1Cn1cccn1 +COCCn1c(SCC(O)CO)nc2ccccc21 +COc1ccc(C(=O)Nc2nc(-c3cccs3)cs2)cc1 +Cc1nn2cccnc2c1C(=O)Nc1cnn(CC2CCCO2)c1 +COc1ccc2c(c1F)C(C=Cc1ccco1)NCC2 +COc1cc(NCc2ccc(C#N)cc2F)cc(OC)c1 +O=C(CC1C(=O)NCCN1Cc1ccoc1)NCCc1cscn1 +CCC(C)C(=O)Nc1cccc(CNC(=O)NCc2cccs2)c1 +COC(=O)CCCCNC(=O)C1COc2ccc(F)cc2C1 +CC(C)C(=O)N1CCCC1C(=O)Nc1ccc(F)cc1F +Cc1cc(C(=O)NCc2cc(-c3ccc(F)cc3F)on2)c(C)o1 +CC(=O)NCc1ccc(C(=O)N2CCCC2C(=O)N(C)C)cc1 +C#CCNC(=O)c1cc2c(C)nn(-c3ccc(F)cc3)c2s1 +COC(=O)c1cc2c(O)ccc(O)c2cc1C(=O)OC +CC(CNC(=O)NCC(C)c1nccs1)c1cccs1 +O=C(c1ccc(OCC2OCCO2)cc1)C1CCC1 +CN(Cc1ccccc1)C(=O)Cn1nc(-c2ccco2)ccc1=O +CNC(=O)Cc1ccc(NS(=O)(=O)C2CC2)cc1 +Cc1cc(NC(=O)CSc2nnc(C3CC3)n2C)n(C(C)(C)C)n1 +N#CC1(NC(=O)CCCC(=O)c2ccc(F)cc2)CCOCC1 +Cc1ccc(S(=O)(=O)Nc2nnc(C(C)C)s2)cc1 +O=C(Nc1nc[nH]n1)C1CCN(c2ccc(Cl)cn2)CC1 +CC(C)C(C(=O)OC1CCc2ccccc2C1)N1CCCC1=O +O=C(CCNS(=O)(=O)c1cccc(C(F)(F)F)c1)NC1CC1 +Cc1ccc(C(=O)Nc2ccc(C)c(N3CCCS3(=O)=O)c2)cc1 +COc1cc(N)c(C(=O)Nc2cc(C)ccc2C)cc1OC +O=S(=O)(Nc1ccc(F)cc1F)c1ccccc1F +COC(=O)c1ccc(-c2noc(-c3ccn(C)c(=O)c3)n2)cc1 +Cc1cc(C(C)NC(=O)CNC(=O)c2cccs2)c(C)s1 +Cc1cnc(NC2CC(C)OC(C)C2)nc1NC1CC(C)OC(C)C1 +COCCCn1c(=O)c2ccccc2n(Cc2ccccc2C)c1=O +CNC(=O)CN1c2ccc(Cl)cc2-c2ccccc2S1(=O)=O +Cc1nc(NC(=O)N(CCCO)Cc2ccncc2)sc1C +O=C(CCc1nc2ccccc2[nH]c1=O)Nc1ccc2ccccc2c1 +CC(C)c1nc(CN2CCNC(=O)CC2c2ccccc2)cs1 +COc1cc(OC)c2c(CCCO)c(C)n(C)c2c1 +Cn1cc(S(=O)(=O)N2CCC(C(=O)NC(C)(C)C)CC2)cn1 +Cc1nc(CSc2nnc(C)n2Cc2ccccc2)cs1 +Cc1noc(C)c1NC(=O)COc1ccccc1C(F)(F)F +CCOC(C)C(=O)OCc1nc(-c2cccc(Cl)c2)no1 +COc1ccc(C(=O)N2CCCN(C(C)=O)c3ccccc32)cn1 +Cn1c(=O)cc(C(=O)N2CCC(O)(CO)CC2)c2ccccc21 +Fc1c(Cl)cccc1CNc1cnn(-c2ncccn2)c1 +CCOC(=O)CCC(C)NC(=O)NC1C2CCOC2C1(C)C +Cn1nc(C(=O)NC2CCCCCC2)c2ccccc2c1=O +COc1cccc(C(=O)N2CCN(Cc3ccccc3)CC2)c1 +CC1CN(Cc2ccc(-n3ccnc3)cc2)CC(C)O1 +O=S(=O)(Cc1cccc(Br)c1)c1nccs1 +COc1ccc(OCCNC(=O)c2c(C)oc(C)c2C)cc1 +Cc1ccc2c(c1)nc(-c1ccccc1)c(=O)n2CCCC#N +CC(C)(C)C(=O)N1CCN(Cc2ccc3ccccc3n2)CC1 +NC(=O)NCCNC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +CC(=O)NCCNC(=O)NCCNc1ncccn1 +c1ccc(-c2nnc(CSc3nncn3Cc3ccco3)o2)cc1 +CNC(=O)c1ccc(OCc2csc(C(C)C)n2)cc1 +CC(=O)Nc1ccc(OC(=O)c2cc(Br)cn2C)cc1 +CCOc1cc(C(=O)Nc2ccc(F)c(C)c2)ccc1OC +CC(C)(C)Oc1cc(CNC(=O)Nc2c(F)cccc2F)ccn1 +O=C(NCC1(O)CCOC1)c1ccc(Br)cn1 +C=CCNC(=O)c1ccc(S(=O)(=O)NCC)cc1 +CCCC1CN(C(=O)CCc2c(C)nc(SC)nc2C)CCO1 +Cc1nnc(SCC(=O)N2CCN(c3ncccn3)CC2)n1C +CC(C)OC(=O)COc1ccc2cc(-c3ccccn3)c(=O)oc2c1 +CC1CN(S(=O)(=O)NCCc2ccc(F)cc2F)C(C)CO1 +CCOC(=O)N1CCN(C(C)C(=O)NCC(F)(F)F)CC1 +CCC1CCCN(C(=O)Nc2ccc(C)cc2OCC(=O)N(C)C)C1 +CCc1c(C)nc2nncn2c1NCc1ccc(C)cc1 +CCN(CC)S(=O)(=O)c1cccc(C(=O)N2CCCC(C)C2)c1 +N#CCOc1ccccc1NC(=O)Cc1ccsc1 +CCC(C)C(=O)N1CCCC(C(=O)Nc2cc(OC)ccc2F)C1 +CCOC(=O)Cn1cnc2c(cnn2-c2cc(C)cc(C)c2)c1=O +Clc1cc(Cl)cc(OCCn2cncn2)c1 +Cn1c(N2CCC(O)C2)nc2cc(C(=O)N3CCCC3CO)ccc21 +COc1ccc(C)cc1C(C)NC(=O)c1cnn(Cc2ccccc2)c1 +Nn1c(SCc2ccc(Cl)cc2)nnc(-c2ccccc2)c1=O +CCOCCCNC(=O)Nc1ccc2sc(NC(C)=O)nc2c1 +COc1cc(OC)cc(C(N)c2nc3ccccc3s2)c1 +Cc1cccc(CC(=O)N2CCN(C3CCCC3O)CC2)c1 +O=C(Nc1ccc(C2=NCCO2)cc1)c1ccc(C(F)(F)F)cc1 +CNC(=O)c1ccc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)cc1 +O=C(C1CC2CCC1C2)N1CCN(c2ccc(O)cc2)CC1 +NS(=O)(=O)c1ccc(CCNCc2cccc3ccccc23)cc1 +CCOc1ccc(C(=O)CN2CCC(=O)CC2)cc1Cl +COCCNC(C#N)c1ccccc1C(F)(F)F +Cc1ccccc1CNC(=O)c1nn(-c2ccccc2F)nc1CO +CCOC(CC)C(=O)Oc1cccc(C(N)=O)c1 +Cc1n[nH]c2c1C(c1ccc(-c3nc4ccccc4n3C)o1)CC(=O)N2 +CCOc1ccc(S(=O)(=O)N(C)C)cc1-c1nc(C(C)C)no1 +CCCn1ccc2sc(C)c(C(=O)NCc3cccs3)c2c1=O +Cc1ccc(S(C)(=O)=O)cc1C(=O)N1CCN(CCO)CC1 +CC=Cc1ccc(OCc2cc(C)on2)c(OC)c1 +Oc1ccc(CNc2ccc3cn[nH]c3c2)cc1Br +Cc1nc(C)c(C(=O)N2CCC(C(=O)N3CCC(C)CC3)CC2)s1 +Cc1ccc2oc(SCC(=O)NCc3ccco3)nc2n1 +CNC(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2C)cc1 +Clc1cc(Cl)c2c(c1)C(c1cccnc1)NCC2 +CSc1ccc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)cc1 +c1ccc(-n2ncc3c(NC4CCCC4)ncnc32)cc1 +Cn1cc(NC(=O)NCc2cnn(-c3ccccc3)c2)cn1 +NC(=O)CCCNC(=O)C1CCN(c2nc3ccccc3o2)CC1 +CC(=O)OC(c1ccc(C)cc1)n1nnc2ccccc21 +COc1ccc(C(=O)Nc2ccc(C(F)(F)F)cc2)cc1OC +N#Cc1cccc(NC(=O)c2ccc(S(=O)(=O)NC3CC3)cc2)c1 +Cc1nc2cc(C(=O)Nc3cccc(F)c3)ccc2[nH]1 +CCCC(=O)N1CCN(c2cc(N3CCOCC3)ncn2)CC1 +CCn1c(N)nc2cc(C(=O)NCc3cnn4ccccc34)cnc21 +CN(C(=O)C1CCCCN1C(=O)c1ccco1)c1ccc(F)c(F)c1 +COC(=O)C(C)(C)NC(=O)c1[nH]c2ccccc2c1Br +COc1cc2c(C(=O)N3CCCC3)nccc2c(N)c1OC +CC(=O)c1cccc(NC(=O)CSc2ccc3nnc(C)n3n2)c1 +Cc1cc(N2CCC(O)CC2)n2c(nc3ccccc32)c1C#N +CCn1c(SCC(=O)c2ccc(C#N)cc2)nnc1-c1ccco1 +FC(F)(F)c1ccc(CNc2ccc3nnnn3n2)cc1 +N#Cc1cc(N2CCOCC2)cc(C(F)(F)F)c1 +CCC(C)C(NC(=O)c1ccc(=O)[nH]c1)c1nc2ccccc2[nH]1 +O=C(CNC(=O)C1COc2ccc(F)cc2C1)NC1CC1 +CCOCc1cccc(NC(=O)Cc2cccc(F)c2F)c1 +Cc1ncc(CNC(=O)c2cnn(-c3ccccn3)c2C)s1 +Cc1cc(C)c(OC(=O)Cn2c(C)c(C)sc2=O)c(C)c1 +CCCn1cc(C(=O)N2CCN(c3ccccc3C)CC2C)c(C)n1 +CCN1C(=O)CCCc2cc(C(O)COC)ccc21 +CC(=O)NCCNC(=O)c1cccc(Nc2ncccn2)c1 +Cc1cccc(NC(=O)CSc2ccc(-n3cccn3)nn2)c1C +CC(=O)NCCc1ccc(OCc2ccccc2)cc1 +CCN(CC)C(=O)c1cc2c(s1)CCC(C(=O)NC(C)C)C2 +Cc1cc(S(=O)(=O)N(C)CCCO)ccc1F +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)c1ccc(C#N)cc1 +COC(=O)c1n[nH]c2ccc(NC(=O)CCc3ccccc3)cc12 +N#Cc1cc(C2NCCc3c(F)cccc32)ccc1F +Cc1cc(C(=O)COC(=O)CCc2c(C)nn(C)c2C)c(C)[nH]1 +Cc1nc2nc(C)c(C(=O)Nc3ccc(Cl)cc3)cn2n1 +CC(C#N)(NC(=O)CNc1cc(F)cc(F)c1)C1CC1 +Cc1ccc(-c2nc3cnccn3c2Nc2ccc(C(N)=O)cc2)cc1 +Cc1cccc(C(=O)NCCNC(=O)c2ccccc2)c1 +CCNC(=O)N1CCN(CCn2nc(C)cc2C)CC1 +Cc1c(CNC(=O)Nc2ccc(-n3cccn3)c(Cl)c2)cnn1C +O=C(NC1CCC(O)CC1)c1cc(Br)ccc1Cl +COc1cc2ncnc(NCC(C)C)c2cc1OC +O=C(c1ccc2c(c1)OCO2)N(CC1CC1)C1CC1 +Cc1ccc(-n2ccc3nc4ccn(N)c(=O)c4cc3c2=O)cc1 +COc1ccc(NS(=O)c2ccc(N)cc2)cc1OC +O=C(NC1CCc2c(O)cccc21)c1cc(=O)[nH]c2ccccc12 +CCC(C)n1ncc(S(=O)(=O)NC2CCCC2)c1N +CC1CN(c2ncnc3[nH]ccc23)CCN1c1ccc2nncn2n1 +CCS(=O)(=O)NCc1ccc(NC(=O)NC(C)C)cc1 +CCOc1ccc(C(=O)N(C)Cc2ccc(Cl)cc2)cc1OC +Cc1cc(NC(=O)c2nccc3c(N)cc(F)cc23)no1 +N#Cc1ccc(-c2noc(COCC3CC3)n2)nc1 +Cn1nc2c(c1C(=O)c1ccc(F)cc1)CCCC2 +CN(C1CCCCC1)S(=O)(=O)c1ccccc1 +COc1ccc(C2NC(=O)c3cccnc3N2)cc1F +COc1ccccc1NC1CCN(C(=O)CCc2cnn(C)c2)CC1 +COC(=O)Nc1snc(C)c1C(=O)NC(C)c1ccc(F)cc1 +COc1cc(C)ccc1OCc1nc(C(=O)N2CCCC2)cs1 +CC(=O)Nn1c(-c2ccccc2)cc2ccccc21 +CC(C)CNS(=O)(=O)c1ccc(C(=O)NCC(F)(F)F)cc1 +Cc1cn2c3c(=O)n(C)c(=O)n(C)c3nc2n1-c1ccc(O)cc1 +CCC(=O)N1CCCC(C(=O)NCC(C)(O)COC)C1 +CC(=O)N1CCN(c2c(C)nn(-c3ccccn3)c2C)CC1 +COCCN(C)C(=O)NC(C)c1cccc(C(F)(F)F)c1 +COc1ccccc1-c1nn(-c2cc(C(F)(F)F)ccn2)c(=O)o1 +Cc1ccc(OCC(=O)N2CCN(C(C)C)CC2)cc1 +CCc1noc(CC)c1CC(=O)N1CCN(c2ccccc2F)CC1 +CC(C)(C)C(C#N)NC(=O)CCOC1CCOCC1 +CCOc1cc(NC(=O)NCc2ccco2)ccc1OC +COC(=O)C1(C)CCN(Cc2cn(C)nc2-c2ccccc2)C1 +COc1ccc(CN(C)C(=O)CCSc2ccccc2)cc1 +Cc1ccc(NC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)cc1F +CCCn1ccc2ccc(NC(=O)NCc3cccnc3)cc21 +CC(C)N(C)C(=O)CN(C)c1cccc2ccccc12 +CN(C)C(=O)c1cccc(CN2CC(n3cccn3)C2)c1 +COCCNC(=O)Nc1ccnn1Cc1ccc(Cl)cc1Cl +c1ccc(-c2ncc(CN3CCc4nncn4CC3)s2)cc1 +Cc1cnc(NC(=O)CCc2ccsc2)c(Br)c1 +CC(=O)c1cccc(NC(=O)NCc2cccc(C#N)c2)c1 +COc1ccc(CC(=O)NC2CNCc3ccccc32)cc1 +O=C(NCC(O)c1ccco1)c1ccc(OCc2ccccc2)cc1 +COc1ccccc1C(C)(C)NC(=O)NCCc1cccnc1 +COC(C)(C(=O)Nc1nc(C(C)=O)cs1)c1ccccc1 +CCNC(=O)CSc1nnc2n1CCCCC2 +CC(C)C(NC(=O)CCC(C)(C)C)c1nnc2ccccn12 +N#CC1CCCCC1OC(=O)CCC(=O)c1ccc(F)c(F)c1 +Cc1cncc(C(=O)NC2CCC3(CCC(=O)N3CC3CC3)CC2)c1 +Cc1csc(=O)n1CCC(=O)Nc1cc(F)c(F)c(F)c1 +O=C(NCc1cccs1)c1cccc(OC(F)F)c1 +CCc1ccc(NC(=O)CSc2nn3cnnc3o2)cc1 +Cn1cc(S(=O)(=O)NCC2CCCO2)cc1C(N)=O +Cc1cc(NC(=O)N2CCCC2)ccc1Oc1cccnc1 +CCc1cc(C(=O)NC(C)C(O)c2ccc(OC)cc2)oc1CC +CC(C)(CNC(=O)Nc1cccc(Cl)c1)N1CCOCC1 +O=c1ccc2cc(O)c(OCc3ccccc3)cc2o1 +Nc1c(N)n(Cc2ccc(Cl)cc2)c(=O)[nH]c1=O +COCc1cccc(-c2nc3ccsc3c(=O)[nH]2)c1 +CCN1c2cc(C(=O)Nc3ccccc3)ccc2C(=O)N2CCCC21 +COc1ccc(NC(=O)c2ccc3c(OC)n(C)nc3c2)cc1OC +CCNC(=O)C1Cc2ccccc2N1C(=O)Nc1ccccc1Cl +CC1(NS(=O)(=O)c2ccc3c(c2)CCO3)Cc2ccccc2C1 +COC(=O)c1cccc(CCNC(=O)NC(C)c2ncc(C)s2)c1 +CC(OC(=O)c1cnc(-c2cnn(C)c2)s1)c1ccccn1 +O=C1CCN(C(=O)c2cc3sc4ccccc4c3s2)CCN1 +COCc1c(C(=O)NCc2ccccc2)oc2ccccc12 +Cc1cccc(Oc2ncccc2NC(=O)c2cnccn2)c1C +c1ccc(Nc2nn3nnnc3c3ccccc23)cc1 +CCNc1ccc(C(=O)NC2CCC(O)CC2)cc1 +CC(=O)c1c(C)[nH]c(C(=O)NCCNc2ncccn2)c1C +Cc1ccc(CNC(=O)CNC(=O)c2cccc(F)c2)cc1 +CCc1cccc(NC(=O)C(C)NC(=O)c2ccccc2)c1 +COc1cccc2cc(C(=O)OC3CCCC(OC)C3)oc12 +N#Cc1ccn2nc(-c3c(F)cccc3Cl)nc2c1 +O=C(C1CCC1)N1CCCc2cccc(OC(F)F)c21 +Cc1nccn1-c1ncccc1NC(=O)Cn1ccc(=O)[nH]c1=O +C#CCCCCC(=O)Nc1ncnc2oc(C)c(C)c12 +Cc1cc(Oc2ncccn2)ccc1NC(=O)NC(C)(CO)C1CC1 +Cn1cc(C(=O)OCCNc2cccnn2)ccc1=O +CC(Nc1nn(C)c(=O)n(C)c1=O)c1cccc(Cl)c1 +N#Cc1ccccc1S(=O)(=O)NCc1cccnc1 +CCc1nnc(NC(=O)C2CCCN2C(=O)c2cccs2)s1 +CC#CCn1c(=O)oc2cc(S(=O)(=O)N(C)C)ccc21 +Cc1cccc(N(CCC(N)=O)Cc2nc(-c3ccco3)oc2C)c1 +CC(OCCCNC(=O)c1cc(F)cc2[nH]cnc12)c1ccccc1 +O=C(Nc1ccc2c(c1)COC2)N1CCCC1COc1ccccc1 +CCc1cc(C(=O)N2c3ccccc3CC2C(N)=O)sc1C +CCC(NC(=O)NCC(C)(C)C(N)=O)c1cc(F)ccc1F +O=C(CNC(=O)CNC(=O)c1ccccc1)NCc1ccccc1 +CC(C)CNC(=O)CCNC(=O)c1cccc2ccoc12 +CC(=O)Nc1c(Sc2ccccc2)nn(-c2ccccc2)c1N +COC(=O)c1ccc2nc(-c3ccc(F)cc3)cn2c1 +CN(CC(=O)N1CCNCC1)C(=O)Nc1cccc(Cl)c1 +CCC(C)(C)NC(=O)COc1cc(Cl)ccc1C(N)=O +CCC(C)OC(=O)CC1C(=O)NCCN1C(=O)c1ccc(OC)cc1 +COC(CNC(=O)N1CCC(C(C)O)C1)c1ccccc1Cl +CC(C)(C)OC(=O)NCC1CCCCN1CC(=O)c1cnccn1 +O=c1cccnn1CCNS(=O)(=O)c1ccccc1F +O=C(CCNc1ccc2nnnn2n1)N1CCOCC1 +COc1cccc(-c2ccc(=O)n(CC(=O)NC3CCCC3)n2)c1 +Cc1ccc2nc3c(cc(C#N)c(=O)n3Cc3ccccc3)c(=O)n2c1 +CCC(C)(C)NC(=O)C(C)OC(=O)c1cccnc1 +Cc1oc(Cc2ccc(Cl)cc2)nc1CCO +O=C(Cc1cc(-c2ccccc2)on1)NCCN1CCOCC1 +CC1(C)Cc2nc(C(C)(C)C)ncc2C(NCc2cccnc2)C1 +Cc1ccc(C)c(S(=O)(=O)N2CCN(CC(N)=O)CC2)c1 +Cc1ccc(SCCC(=O)C(C#N)c2ccccn2)cc1C +C=CCn1c(SCC(=O)NC(C)(C)C)nnc1-c1ccco1 +Cc1ccc(NC(=O)NCC(C)(C)c2ccncc2)cn1 +CCC(=O)N1CCC(C)(C(=O)NCc2cc(OC)cc(OC)c2)CC1 +Cn1cnnc1-c1ccc(NC(=O)c2ccoc2)cc1 +CS(=O)(=O)N1CC2CCC(C1)N(C(=O)c1ccc[nH]1)C2 +Cc1cc(NC(=O)CN(C)C(=O)CC2CC3CCC2C3)no1 +CC1CC1c1ccc(CN(C(=O)Cc2ccc[nH]2)C2CC2)o1 +O=C(CCSc1ccccc1)NC1CC2CCC1C2 +Cc1csc(NC(=O)c2cc(C3CC3)nc3c2c(=O)[nH]n3C)n1 +CN(Cc1ccc(F)cc1)C(=O)CSc1ccc(O)cc1 +CCNC(=O)c1cc(S(=O)(=O)N(CC)CC)ccc1C +COc1cc(C)c(C)cc1S(=O)(=O)C(F)F +CN(C)C(=O)c1cn(CCC#N)nc1-c1cc2ccccc2o1 +O=C(NCc1ccco1)C1CCCN1C(=O)c1ccc2c(c1)OCO2 +CC(C)CNC(=O)CNC(=O)c1cc2sccc2n1C +COCC1(C(=O)N(C)Cc2nnc(-c3ccccc3)o2)CCC1 +O=C(c1ccoc1)N1CCCC(c2nc(-c3ccccc3)n[nH]2)C1 +O=C(CSc1ccc(F)cc1)NCc1cccnc1 +COc1cccc(OC)c1OCCSc1nc(C)cc(O)n1 +CCCCn1c(CCCO)nc2cc(F)ccc21 +Cc1c(OCC(=O)Nc2ccc3c(c2)OCO3)c(=O)ccn1C +C=CCNC(=O)CSc1nnnn1-c1ccc(OC)cc1 +COCC(=O)N1CCC(c2sccc2C)C(O)C1 +COc1ccc2cc(CNC(=O)c3ccc(C)o3)ccc2c1 +CCc1c(C(=O)N2CCC(C(N)=O)C2)cnn1-c1ccc(F)cc1 +OCCc1nnc(COc2ccc3c(c2)OCO3)o1 +CCOc1ccc(Nc2nc(N)c(C(C)=O)s2)cc1 +CC(C(=O)c1c[nH]c2ccccc12)N(C)CCC#N +O=C(NCCCN1CCCC1=O)c1cc(Br)ccc1O +c1ccc(COCC2CN(Cc3cccnc3)Cc3ccnn3C2)nc1 +Cc1ccc(S(=O)(=O)N(C)Cc2nc(-c3ccncc3)no2)cc1 +CC(C)c1cc(CNC(=O)C2CC(=O)N(C(C)C)C2)on1 +CCCN1C(=O)c2cccc3c(S(N)(=O)=O)ccc1c23 +CCOc1cc(NC(=O)c2cccnc2)ccc1OC +COc1ccc(N)c(S(=O)(=O)N2CCOCC2)c1 +O=c1[nH]nc2c(Oc3ccc(Cl)cc3)nccn12 +O=c1[nH]c(CSc2ccc(F)cc2)nc2ccsc12 +Cc1csc(C2CCN(C(=O)c3ccc(C)s3)CC2)n1 +Cc1ccc(NS(=O)(=O)c2ccc(-c3nnc(C4CC4)o3)o2)cc1 +CC(C)c1cc(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)n[nH]1 +O=C(CCc1nc2ccccc2[nH]1)NCCC(=O)Nc1cccnc1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1cc(C)c(C)s1 +Cc1cccc(Cl)c1S(=O)(=O)N(C)C(C)C +COc1ccc(-c2nc3cc(F)ccc3n2C)cc1O +Cc1ccc(NC(=O)Nc2cc[nH]n2)c2cccnc12 +COc1c(Br)cccc1CCNC(=O)C1CNC(=O)C1 +CCCCC(=O)Nc1cccc(S(N)(=O)=O)c1C +CC(C)(C(=O)NCc1ccncc1)c1ccc(F)cc1 +CCc1nnc2n1NC(c1ccc(C)cc1)CS2 +Cc1ccc(CC2CCCN2C(=O)C2CCCN2C(=O)C2CC2)cc1 +Cc1cc(C)cc(-c2ccc(C(=O)NCC(C)O)o2)c1 +COc1ccccc1Nc1ncnc(NCCC(C)C)c1N +O=c1[nH]c(=O)n(Cc2ccccc2C(F)(F)F)cc1Cl +N#Cc1ccc(Nc2ccc3c(c2)OC(F)(F)O3)nc1 +CC(C)N(CCC#N)S(=O)(=O)c1cccc(F)c1 +Cc1cc(C)cc(NC(=O)c2cc3cccnc3n(C)c2=O)c1 +Cc1ccc(-n2ncc3c(C)nn(CC(N)=O)c(=O)c32)c(C)c1 +CC(=O)NCCCCCC(=O)Nc1ccnc2ccnn12 +C#CCOc1ccccc1CNc1ccc2oc(C)nc2c1 +Cn1cc(NC(=O)NCc2ncc[nH]2)cc(Br)c1=O +Cc1ccc(C(=O)NCC(=O)N(C)CCOc2ccccc2)cc1C +COc1ccc(C(=O)CN2CCc3ccccc32)c(OC)c1 +CC(=O)N1c2ccc(S(=O)(=O)Nc3ccccn3)cc2CC1C +O=C(NCc1ccccc1F)c1sccc1Br +CC(=O)NC(C(=O)OC(C)c1ccccn1)C1CCCC1 +CCOc1cc(C)c(C2CCC(=O)C2)cc1Cl +CC(C)c1ccc(C2CCCN2C(=O)c2cc(C(N)=O)c[nH]2)cc1 +Cc1cc(NC(=O)C(NC(=O)c2ccc(Cl)cc2)C(C)C)n(C)n1 +CCCCc1nnc(NC(=O)c2cnc3ccc(C)cn23)s1 +COC1CCC(c2cccc(C)c2)n2nc(N)nc21 +O=C(CCCNC(=O)c1cnn2ncccc12)Nc1ccccc1 +CCCn1cnc2c(Cl)cc(Cl)cc2c1=O +Cn1nccc1CNC(=O)NC(c1ccc(F)cc1)C(C)(C)C +COC(=O)Cc1nc2c(Br)cccn2c1N +O=C(CCCCO)Nc1cc(Cl)ccc1Cl +O=C(NCc1ccc(OCc2ccccn2)cc1)Nc1cccnc1 +CCn1cnnc1CNC(=O)c1ccc(Br)cc1C +CC(C)OCCC(=O)Oc1ccc(Br)cc1F +CC(C)c1cc(NC2c3ccccc3CC2O)n2nccc2n1 +Cc1ccc(S(=O)(=O)N2CCCC2C)c2c1NCCC2 +CCn1nc(C)cc1NC(=O)COc1ccccc1 +CC(C)n1cnnc1SCC(=O)NC1(C#N)CCCCC1 +COCCNC(=O)c1cc2sccc2n1C(C)C +NC(=O)c1ccccc1NC(=O)Cc1ccccc1Cl +CN1CCN(C(=O)c2cnc(-c3ccccc3)nc2N)CC1 +CCC(CC)NC(=O)NCC(c1ccccc1)N1CCOCC1 +COc1ccc(CNC(=O)c2csc3c2CCCC3)cc1 +O=C(NCC1Cn2nnc(-c3ccsc3)c2CO1)c1ccc[nH]1 +CCN(CCC#N)S(=O)(=O)c1ccc(OC)cc1OC +CC(O)(CNC(=O)c1ccc(C(F)(F)F)nc1)c1ccc(F)cc1 +Cc1cccc(CS(=O)(=O)NCC2CN3CCCCC3CO2)c1 +CC(CS(=O)(=O)N1CCNCC1)C(=O)NCC1CCCO1 +CS(=O)(=O)N1CCCC(C(=O)CCc2ccccc2)C1 +CCOCC1CCCN(C(=O)CSc2ccc3c(c2)CCC3)C1 +O=C(NCCS(=O)(=O)c1ccccc1)Nc1cccnc1 +CC(O)CN(C)C(=O)COc1ccc(Cl)cc1Cl +O=C(CN1CCN(C(=O)C2CCC(=O)N2)CC1)Nc1ccc(F)cc1 +Cc1cccc(OC(=O)C2CCN(c3cnccn3)CC2)c1C +O=C(CNC(=O)C1CCCCC1)Nc1nc2ccccc2[nH]1 +O=C(NCCNC(=O)C1CC1)NC1CCCc2ccccc21 +CC(=O)c1c(C)[nH]c(C(=O)C(C)Sc2ncn[nH]2)c1C +NC(=O)COC(=O)Cc1ccc(OC(F)(F)F)cc1 +O=C(CCCOc1ccccc1Cl)NC1CC1 +CC(NC(=O)NCC1(C)CCCC1)c1ccncc1 +O=C(Cn1nnc(-c2ccc(Cl)cc2)n1)NCCc1ccccn1 +CC1CCCCC1OCCSc1nnnn1C1CC1 +Cc1csc(C(C)NC(=O)NCc2ccccc2-n2cccn2)n1 +CCN(C(=O)N(C)Cc1cnc(N(C)C)nc1)C(C)C +Cc1cc(C)c2oc(-c3ccc(-n4cnnc4)cc3)nc2c1 +CC(C)(C)C(=O)N1CC(=O)N2CCc3ccccc3C2C1 +COC(=O)c1ccc(CN(C)Cc2cc(C(N)=O)cs2)cc1 +COc1nc2ccccc2cc1-c1ccc(SCC(N)=O)cc1 +CCOC(=O)CSc1nc(-c2ccccc2)cn1N +CC(C)(C)c1ccc(OCCn2nncc2CO)cc1 +CC(=O)NCCNC(=O)Cc1cn2ccsc2n1 +CC(C)Nc1ncnc(-n2cnc3ccccc32)c1N +Cc1cc(C(=O)Nc2ccc(-c3cn4cccnc4n3)cc2)on1 +Cc1c(C(=O)NCc2ccc(C(N)=O)o2)cnn1-c1ccncc1 +C=CCNC(=O)C1CSc2nccc(=O)n2C1 +CNc1nc2cc3c(cc2s1)CCCN3S(C)(=O)=O +CC(NS(=O)(=O)c1ccc(=O)[nH]c1)c1ccccc1 +Cc1cc(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)on1 +COc1ccc(CNC(=O)NC(C)c2nncn2C)cc1F +Cc1ccc(NC(=O)c2ccc3nnc(C)n3c2)cc1S(C)(=O)=O +CC(C)CNC(=O)N1CCCC(CC(=O)Nc2ccc(C#N)cc2)C1 +CCCCC(=O)NCC(=O)Nc1c(C)cccc1C +CCOc1cc(C2NC(=O)c3ccccc3O2)ccc1OC +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)NCC(N)=O +COc1ccc(C(=O)NCC(=O)NCCc2ccc(F)cc2F)cc1 +C#CCN(CCc1ccncc1)Cc1cccc(C)n1 +O=C1N(CCO)CCCC12CCN(c1nccc(C(F)(F)F)n1)C2 +Cn1cc(NC(=O)NC2CCCc3occc32)cn1 +O=C(NCc1ccnc(-n2cccn2)c1)c1cc(-c2ccccc2)no1 +CCOc1cc(CC(=O)CC)ccc1OC(C)C +Cc1nc2cc(NC(=O)N3CCOCC3)ccc2n1-c1ccccc1 +CCOCCN(C)C(=O)Nc1c(C)cccc1Cl +COc1ccc(C(=O)N(C)CCOc2ccccc2)cc1OC +CCc1cccc(NC(C)c2cccc(-n3cnnn3)c2)c1 +CCN(Cc1cccc(F)c1)C(=O)COc1ccccc1F +C=CCn1nnnc1-c1cc(Cl)cc(Cl)c1 +CCOc1ccc(C(=O)N(CC)Cc2ccccc2Cl)cc1OC +O=C(Cn1ccc(=O)[nH]c1=O)NCC(c1ccccc1)c1ccccc1 +CC(NC(=O)c1ccc2c(c1)OCC(=O)N2)c1ccccc1Cl +CC(C)(C(=O)N1CCCC(N2CCOCC2)C1)c1ccccc1 +Cc1ccn2cc(-c3ccc(NC(=O)Cc4cc(C)on4)cc3)nc2c1 +Cc1cccc(CN2CCCC(c3cncc(-n4ccnc4C)n3)C2)c1 +CC(C)C(=O)NC1CCCN(C(=O)CNc2ccc(C#N)cc2)C1 +Cc1[nH]ncc1CCCNC(=O)N1CCN(Cc2cccnc2)CC1 +C#CCC(OC(=O)c1cc(F)cc(F)c1)c1ccccn1 +Cc1c(CN(C)c2cc(-c3ccccc3)nc3ccnn23)cnn1C +Cc1cc(NCCOCCO)n2c(nc3ccccc32)c1C#N +NC(=O)Cc1csc(NC(=O)c2ccc(Cn3cccn3)cc2)n1 +N#Cc1cc(F)ccc1NC(=O)Cc1c(F)cccc1F +O=C(Cn1cccn1)NCC(C1CCOC1)N1CCOCC1 +O=C(CC(F)(F)F)Nc1ccc(C#CCO)cc1F +Cc1nn(C)c(-c2ccc3c(c2)C(C)(C)C(=O)N3)c1N +CCOC(=O)c1cnn(-c2cccc3ccccc23)c1N +CCOc1ccc(CC(=O)Nc2cccc(NC(=O)CC)c2)cc1 +CC(C)c1ccc(C(=O)CCC(=O)N2CCOCC2)cc1 +CC(O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O +CC1CCC(NC(=O)CN2CCN(c3nccs3)CC2)CC1 +CC(C)CC(=O)N(Cc1nccn1Cc1cccc(F)c1)C1CC1 +C#CCn1c(CCCO)nc2cc(OCCC)ccc21 +Cc1ccc2c(c1)nnn2C(=O)c1ccccc1F +CC(=O)N1CCc2c([nH]c3ccccc23)C12C(=O)Nc1ccccc12 +Cc1cc(C(F)(F)F)cc(=O)n1Cc1nc(C(C)C)no1 +COc1ccc(C(NC(=O)c2cnc3onc(C)c3c2)C2CC2)cc1 +C=CCNC(=O)c1cc(S(N)(=O)=O)ccc1N +CC(=O)NCC1CCCN(C(=O)NC(C)CCc2ccccc2)C1 +COc1c(F)ccc2c1CCNC2c1cccnc1F +Cc1ccc(C)c(CN(CCC#N)CCN2CCOCC2)c1 +CC(O)CN1CCN(C(=O)c2cnc(-c3ccco3)s2)CC1 +O=C(Nc1cccc(C(=O)OCc2nncn2C2CC2)c1)NC1CC1 +CCn1nc(CC(C)C)cc1C(=O)N(C)C(C)c1cncs1 +CC1(CC(=O)N2CCOCC2C2CC2)CCCCC1 +c1csc(C2NCCc3nc4ccccc4n32)c1 +O=C(c1ccco1)N1CCN(c2ccc(Cl)cc2)CC1 +Cc1ncc(CNS(=O)(=O)c2ccccc2C(F)(F)F)s1 +CNC(=O)c1ccc(NC(=O)NCC(=O)N2CCCCC2)cc1 +NC(=O)c1ccc(Cn2nnc(-c3cccc(C(F)(F)F)c3)n2)cc1 +CC1CCN(C(=O)Cc2cccc(OCC#N)c2)CC1 +CCOC(=O)c1cnc(SC)nc1C(F)(F)F +CCc1ccc(C(C)NC(=O)CN2C(C)COCC2C)cc1 +CC1Oc2ccc(-c3cc(CO)on3)cc2NC1=O +CC(C)(C)c1nnc(SC(C(N)=O)c2ccc(F)cc2)n1N +Cc1cccc(NC(=O)CN(C)C(=O)c2cccc3c2OCCO3)n1 +CCOC(=O)C(C)(NCC(C)C)c1ccccn1 +Cn1ccnc1Sc1nnnn1-c1ccccc1 +COC(=O)C1CCCCN1Cc1cccc(-n2cccn2)c1 +Cc1cc(C)c(CNC(=O)c2cncn2-c2ccc(F)cc2)c(=O)[nH]1 +CCOc1ccc(C(=O)C(C)N)cc1NC(C)=O +CCOC(=O)c1c(-c2cc(OC)ccc2OC)c[nH]c1C +COc1ccc(CNC(=O)c2c(F)cccc2F)cc1 +COC(=O)c1cc2c(=O)n(C)c(=O)n(C)c2nc1N(C)C +CC(C)NC(=O)NCC(=O)N1CCn2nnc(-c3ccccc3)c2C1 +CCN(CCO)S(=O)(=O)c1cc(Cl)ccc1C +Cn1cc(CN2CC(C(=O)Nc3cnccn3)CC3OCCC32)cn1 +CCC(CC)c1c(CO)nnn1-c1nc2c(s1)CCCC2 +COC(=O)C1CCCc2c1[nH]c1cc(OC)ccc21 +COC(=O)C1C2C=CC3C(C(=O)OC)C4C=CC1C4C23 +CC(=O)NCCCS(=O)(=O)c1ccccc1Br +N#Cc1ccc(C(=O)NCc2ccc(-n3ccnc3)cc2)cc1 +Cc1cnn(C2CN(c3cc(C)nc4ncnn34)C2)c1 +CCOC(=O)COC(=O)c1ccc(C)c(OC)c1 +O=C(Cn1nnc(-c2ccc(Cl)cc2)n1)Nc1ccccc1F +CC(C)=CCOc1cccc(C(=O)NC(C)(C)C(N)=O)c1 +Nc1ccc(OCCc2ccc3c(c2)OCCO3)nc1 +Fc1ccc(C2NCCc3cc4[nH]ccc4cc32)cn1 +CNC(=O)CNc1nc(C(F)(F)F)nc2ccccc12 +CCNC(=O)C(C)NC(=O)Cc1ccc(C)s1 +NC(=O)CC1CCN(C(=O)c2ccnc(OC3CCC3)c2)CC1 +O=C(NC1=CC2=CC=NC2C=C1)c1cccc(-n2cccc2)c1 +Cn1cccc1C(=O)Nc1cccc2ncccc12 +CC(=O)Nc1cc(NC(=O)N(C)CCOCC2CC2)ccc1F +CCOc1ccc(C(O)CNc2ccccc2F)cc1 +CCC(C)N(C)C(=O)NC1CCC2(CC1)OCCO2 +O=C(NCC#CCOc1ccc(F)cc1F)c1ccco1 +Cn1ccsc1=NC(=O)Cc1cn(C)c2ccccc12 +O=C(Nc1ccc2c(c1)COC2)N1CCCC1CO +O=C(NCCc1nnc2ccccn12)c1ccc2c(c1)N=C(O)CO2 +O=C(Nc1nc(-c2ccncc2)cs1)c1cc2ccccc2o1 +O=C(Nc1ccc2c(c1)N(C(=O)C1CC1)CC2)c1cccc(F)c1 +Cn1cc(C#N)cc1C(=O)NCc1ccnc(OC2CCC2)c1 +CC(=O)c1cc2c(cc1Br)CCN2C +COc1ccc(C2CC2C(=O)N2CCn3c(C)nnc3C2)cc1 +N#Cc1ccc(-c2ccccc2)n(CC(=O)N2CCCC2)c1=O +O=C(c1cc(F)cc(F)c1)N1CCN(Cc2ccccn2)CC1 +COc1cccc(Cc2nc3c([nH]2)CC(C)(C)CNC3=O)c1OC +CC(=O)NC1CCN(c2ncnc3c2c(C)nn3C)C1 +CN(C)S(=O)(=O)c1cccc(Cn2ncc(=O)c3ccccc32)c1 +CC1CN(C(=O)COc2ccc(Cl)c(Cl)c2)CC(C)O1 +Cc1noc(C)c1CCCNC(=O)NCc1ccnn1C +Cc1oc(C)c(C(=O)Nc2ccc(N3CCOCC3)nc2)c1C +CCOc1cccnc1C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +N#Cc1ccc(N2CCC(NC(=O)NC3CCCC3)CC2)nc1 +CCN(C)C(=O)c1cc(Br)ccc1Cl +COc1ccc(Cn2c(=O)n(C)c3ncncc32)cc1F +Cc1ccccc1C1(O)CCN(c2ccc3cc[nH]c3n2)C1 +CCN(CC)C(=O)c1ccccc1NC(=O)Cc1cccs1 +Cc1sc(NC(=O)c2ccc3nccnc3c2)c(C#N)c1C +CCC(C)c1ccc(C(O)CN2CCN(C(C)=O)CC2)cc1 +O=C(C1CC=CCC1)N1CCC(Oc2cccnc2)CC1 +CCN1CC(c2nc3ccccc3n2CCC(C)C)CC1=O +CC(=O)C(C)Oc1c(-c2ccco2)oc2cc(C)ccc2c1=O +Cc1nc(C(C)N(C)C(=O)Cc2cn3ccsc3n2)c(C)s1 +CCN1CCc2nc(NC(=O)CCOCC(F)(F)F)sc2C1 +CC(=O)N1CCCC(OCc2ccc(F)c(F)c2)C1 +CNC(=O)c1cc(C)ccc1NC(=O)c1coc(-c2ccccc2)n1 +CCc1nnc(NC(=O)C2CC(=O)N(c3ccccc3F)C2)s1 +Cc1cc(S(=O)(=O)N2CCCC(C)C2)cc2c1NC(=O)C2(C)C +CC(C)C1CCCN1C(=O)c1cnc2c(cnn2C2CCCC2)c1 +CC(C)Cc1nc(Cn2nnc(-c3ccccc3)n2)no1 +O=C1CN(Cc2ncc(-c3cccs3)o2)CCN1 +Cc1cc(NC(=O)COc2ccc(N(C)C(N)=O)cc2)n(C)n1 +O=C(NCc1ccco1)C1CCCN1c1ccnc(-c2ccccc2)n1 +CCCC(=O)N1CCCc2c(Cl)ccc(F)c21 +Cn1cc(-c2ncc(C(=O)NC(C#N)c3ccccc3F)s2)cn1 +CCOc1ccccc1-c1cc(CO)nn1CC(N)=O +Cc1cc(-n2ccc(C(F)(F)F)n2)ccc1CO +COc1cc(C)c(CN2CCCC(CN3CCOCC3)C2)cc1OC +CC(=O)Nc1cc(NCC(=O)Nc2ccccc2C)ccc1C +CC(OC(=O)c1cccs1)C(=O)N1CCN(c2ncccn2)CC1 +CNC(=O)c1nsc(C(=O)NC2CCCCC2)c1N +Cc1cc(C)c(C(=O)N2CCN(C3CCCCC3O)CC2)c(=O)[nH]1 +Cc1ccc(C)c(CC(=O)NCc2cc(C)oc2C)c1 +Cc1sc(-n2cccc2)nc1C(=O)NCCc1cccs1 +CCC(NCc1ccccn1)C(O)c1ccc(F)cc1 +O=C(Nc1cc(Cl)cc2c1OCC2)NC1C=CC(CO)C1 +Fc1cccc(CSc2nnc3ccc(-c4ccncc4)nn23)c1 +O=C1CCC(NC(=O)c2csc3c2CCCC3)CN1 +O=C(CC12CC3CC(CC(C3)C1)C2)N1CCOCC1 +c1cncc(CN2CCN(c3ncnc4[nH]ncc34)CC2)c1 +Cc1cc(C(=O)NCCCO)c2cnn(Cc3cccs3)c2n1 +Cc1ccccc1OCC(=O)Nc1sc(C)c(C)c1C(N)=O +Cc1cc(C#N)c(N(C)C)nc1-c1ccc2c(c1)OCCCO2 +O=C(NCCC1CCCO1)Nc1ccc(OCC2CCCO2)cc1 +CSc1ccc(-c2ccc(-n3cccn3)cc2)nn1 +COCc1nnc(-n2nnc(CO)c2C2CCCCC2)s1 +O=C(c1ccc(Cl)cc1F)N1CCN(c2ccc(F)cc2)CC1 +O=S(=O)(CCc1ccncc1)NCc1cn[nH]c1 +COc1cccc(NCc2ccc(F)c(OC)c2)c1 +CCOc1cc(=O)c(C(=O)NC2CCCC2)nn1-c1ccc(C)cc1 +N#Cc1cccc(COc2ccc(NC(=O)NCc3ccon3)cc2)c1 +CC(C)COC1CCN(C(=O)c2cc3ccccc3c(=O)[nH]2)CC1 +COc1cccc(COC2CCCN(C(=O)C3CCCC3)C2)c1 +CCN(Cc1ccc(OC)cc1OC)c1cccc(N)c1 +Cc1cnc(NC(=O)c2nn(CC(C)C)c(=O)c3ccccc23)s1 +COc1ccc(CCNc2ncnc3c2cnn3C)cc1OC +COc1ccc2c(c1)C(CSc1ncccn1)NCC2 +Cc1ccc(SCC(=O)OCc2cc(=O)n3oc(C)cc3n2)cc1 +CCC1CN(C(=O)c2cc(C3CC3)no2)CCN1C(C)C +Cc1ccccc1NC(=O)Cn1c2ccccc2c(=O)c2ccccc21 +CC(O)CN1CCN(C(=O)c2cccc3c2OCO3)CC1 +CCC(C)n1nccc1NC(=O)C1CC(=O)N(C)C1 +C#CCN(Cc1ccc(F)cc1)C(=O)NCCOC +COC(=O)c1nnn(Cc2ccccc2Cl)c1N +Cc1cc(C)n(C(=O)C2CC(F)(F)C2(F)F)n1 +COC(=O)c1ccc(NS(=O)(=O)c2ccc(OC)c(C)c2)cc1 +CCOc1ncccc1CNS(=O)(=O)c1ccccc1 +CCN(CC)C(=O)CCC(=O)N1CC(C)(C)Sc2ccccc21 +OCCN1CCN(Cc2nnc(Cc3ccccc3)o2)CC1 +c1ccc2cc(OCCCn3ccnc3-c3cnccn3)ccc2c1 +CC(NC(=O)c1cccc(OCc2ccccc2)c1)c1cccnc1 +CN(C)C(=O)c1cccc(CCNC(=O)Cc2ccc[nH]2)c1 +CCc1ccccc1NC(=O)c1ccc(OCC(N)=O)c(OC)c1 +CCCCN(C)C(=O)CNC(=O)c1cccc(F)c1 +Cn1c(C(=O)N2CCN(C(=O)C(C)(C)C)CC2)cc2ccccc21 +CCCC(=O)Nc1ccccc1C(=O)NC1CCCC1 +CCc1nc(CC(=O)NCc2ccc(C(=O)N(C)C)cc2)cs1 +O=c1cc(CSc2nncs2)c2cc(Cl)c(O)cc2o1 +Cc1ccccc1-n1cc(C(=O)Nc2ccc(-n3ccnc3)nc2)cn1 +CCC(C)C(C)NC(=O)c1cc(OC)c2c(c1)OCCO2 +O=C(NC(CC(F)(F)F)c1ccc(F)cc1)c1cc2occc2[nH]1 +CC(C)C(C)OC(=O)c1ncn(-c2ccccc2)n1 +CC(C)OC(=O)C(C)N(C)C(=O)c1cn(C)nc1-c1cccs1 +O=C(NCC(F)(F)F)c1ccc(-n2ccc(C(F)(F)F)n2)cc1 +Cc1ccccc1-n1cnc(C(=O)N(C)CC(=O)N(C)C)n1 +COc1ccc(NC(=O)c2cc(F)ccc2-n2cnnn2)cc1OC +CSc1ccc(Cl)c(C(=O)Nc2ccc3c(c2)NC(=O)CO3)c1 +Cc1cccc(C(=O)NCCC(=O)Nc2ccc(F)cc2)c1 +Cc1ccc(S(=O)(=O)N(C)CCCO)c(C)c1 +CC(C)N1CC(C(=O)Nc2cccc(Cl)c2Cl)CC1=O +O=C(Nc1cc(F)cc(F)c1)C1CCN(C(=O)c2ccco2)CC1 +CCNC(=O)Cn1ccsc1=NC(=O)c1cccc(Cl)c1 +CCNc1ncnc(Nc2cc(C)ccc2OC)c1N +CC(NC(=O)c1cc(C(N)=O)cs1)c1cccc(OC(F)F)c1 +O=C(CNc1ccc(F)c(F)c1F)N1CCCCCC1 +O=C(C1CCCO1)N1CCC2C1CCN2c1nncs1 +Cc1oc(-c2ccccc2)nc1C(=O)N1CCc2sccc2C1 +CNC(=O)C1(C)CN(Cc2c[nH]nc2-c2ccccc2)CCO1 +CC(C)CC(C)OC(=O)Cn1ncc(=O)c2ccccc21 +CCn1c(CN2CCOCC2)nc2c1c(=O)[nH]c(=O)n2C +O=C(c1cc(F)cc(F)c1)N1CCCCC1C1OCCO1 +COc1cc(C(F)(F)F)c(C(=O)Nc2c(C)cccc2C)cn1 +Cc1cn(-c2ccccc2)nc1NC(=O)NC(CO)c1ccccc1 +CC1(C)CCCC1NC(=O)Nc1ccc2c(c1)COC2 +O=C(NCc1ccon1)Nc1cccc(Cl)c1Oc1cccnc1 +CCn1c(CC2CCN(C(=O)c3ccoc3)C2)nc2cccnc21 +Cc1ccc(Cn2cnc3c(cnn3-c3ccc(F)cc3)c2=O)cc1 +COC(=O)c1cccc(CCNC(=O)Nc2cc(C)n(C)n2)c1 +COc1ccc(OC)c(CN(C)C(=O)c2cnccn2)c1 +Cc1ccn2c(=O)c(C(=O)NCc3cccnc3)cnc2c1 +CC(=O)Nc1nc(C2CCCN2c2cnccn2)cs1 +CN(CCc1ccc(F)cc1)C(=O)C1CCN(CC(F)(F)F)CC1 +COC(=O)c1cc(F)c(N2CCCC2)c(F)c1F +CC(=O)Nc1ccc(OCC(=O)NC(C)c2ccc(F)cc2)cc1 +O=C(NC(c1ccccc1)C1CCCC1)C1COCCO1 +Cc1nn(C(C)C)c(C)c1NC(=O)c1cccc2cccnc12 +CNC(=O)c1cn[nH]c1C1CCCN1C(=O)Cc1csc(C)n1 +Cc1coc2c1C(NC(=O)c1cccc(Cl)c1)CCC2 +CCCCNC(=O)CS(=O)(=O)c1ccccn1 +Cc1cc(NC(=O)CCSc2ncn[nH]2)no1 +C=CCn1c(CN(C)C(=O)c2ccncc2)nc2ccccc21 +NC(=O)Cc1ccccc1NC(=O)c1ccc(OC(F)F)cc1 +CN(C)c1ccccc1NC(=O)CN1C(=O)CSc2ccccc21 +Cc1cn[nH]c1C1(C)CCN(C(=O)c2ccc(F)cc2)CC1 +O=C(NCc1ccccn1)c1cn(-c2ccc(F)cc2)nn1 +Cc1sc(C(=O)NC(C)C)cc1S(=O)(=O)N1CCOCC1 +COC(=O)C(NC(=O)c1cnc2ccc(C)cn12)C(C)(C)C +CCCCC(=O)Nc1ccc(NC(=O)c2c(C)n[nH]c2C)cc1 +Cc1ccc(Cl)cc1-c1nc2c(CO)cccn2c1N +Cn1c(=O)cc(-c2ncnn2CCO)c2ccccc21 +CCOc1cc(C2NC(=O)c3cccnc3N2)ccc1OC +Cc1csc(NC(=O)c2cc(F)ccc2F)n1 +CNC(=O)CSc1ncc(-c2ccccc2)n1C1CC1 +CCC(=O)Nc1cccc(NC(=O)CNC(=O)C(C)(C)C)c1 +CCCc1c(C(=O)OC)cnn1-c1cccc(C#N)c1 +CCCCNc1c(C(=O)OCC)c(=O)[nH]c2c(C)cccc12 +CCNC(=O)CSc1nc(-c2cc(Cl)ccc2OC)n[nH]1 +N#Cc1cccc(CNC(=O)c2cnc(Cc3ccccc3)s2)c1 +CCCC(=O)Nc1cccc(CNS(=O)(=O)c2cccs2)c1 +O=C(CCn1cnc2ccccc2c1=O)NCc1cscn1 +Cc1cccc(C2(C(=O)NC3CCCc4c3cnn4C)CC2)c1 +O=C(CCOc1cccc(F)c1)N1CCCC(O)C1 +COC(=O)c1ccc2[nH]c(-c3ccc(O)cc3)nc2c1 +O=C(NCCCc1ccco1)c1ccc(N2CCOCC2)cc1 +CC(C)c1ccsc1C(=O)NCCc1cnn(C)c1 +N#Cc1c(-c2ccc(F)cc2)nn(-c2cccc(F)c2)c1N +CC(C)NC(=O)Nc1ccc(OCC(=O)N(C)C)cc1 +CCCCCNC(=O)CS(=O)(=O)c1ccc2ccccc2c1 +CC(c1ccccc1F)N(C)CC(=O)c1c(N)n(C)c(=O)n(C)c1=O +Cc1nn(C(=O)c2ccc(F)cc2)c(C)c1Cl +CN(CC(O)C(F)(F)F)S(=O)(=O)c1cc2ccccc2o1 +O=C(Nc1ccc2c(c1)C(=O)NCC2)c1cc2ccccc2o1 +Cc1nnc2sc(-c3cc(Cl)ccc3Cl)nn2c1=O +COc1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1Cl +CC(=O)Nc1ccc(Cl)c(C(=O)NCC2CCC(C)(C)CC2)c1 +Cc1cccc(S(=O)(=O)NC(CO)Cc2ccccc2)c1 +Cc1cc(NC(=O)NC(C)c2ccccc2C(F)(F)F)no1 +CC(=O)c1cccc(OC(C)C(=O)Nc2cc(C)on2)c1 +CCOc1ccc(F)cc1NC(=O)c1ccc(N2CCOC2=O)cc1 +Cc1ccc(C(C)NC(=O)CCc2ccc(C#N)cc2)o1 +CCC1CN(C)c2ccccc2CN1S(C)(=O)=O +Cc1noc(C)c1CC(=O)OCC(=O)c1ccc2c(c1)NC(=O)CO2 +Cc1c(C(C)NC(=O)c2cnn(C)c2)oc2ccc(F)cc12 +C=CCN(Cc1cccs1)S(=O)(=O)c1cc(C)sc1C +CC1Oc2ccc(NC(=O)CCc3cccs3)cc2NC1=O +Cc1nc(C(=O)NC(C)Cc2ccccc2C)cs1 +O=C(NCCNS(=O)(=O)c1cccc(Cl)c1)NC1CCCC1 +CC1CN(c2ccc(Br)cc2N)CC(C)O1 +NC(=O)CSc1nnc(-c2cccc(Cl)c2)n1-c1ccccc1 +O=S(=O)(CC1CCCC1)N1CCCN(c2nccs2)CC1 +CC(=O)N(C)Cc1ccccc1NC(=O)N(C)CCc1cccs1 +CN(CC(N)=O)C(=O)c1ccc(OCC(N)=O)cc1 +CCC(C(=O)N1CCCN(c2ccccc2C)CC1)N1CCOCC1 +CC(=O)c1ccc(OCCN2CC(C)OC(C)C2)cc1 +Cc1cnn(C2CCCN(C(=O)c3cc[nH]n3)C2)c1 +Cc1nnc(N2CCN(C(=O)C3CCCCC3)CC2)o1 +CCOC(=O)COc1ccc(Br)cc1C#N +COc1ccc(C2NC(=O)NC3=C2C(=O)N(CC(C)C)C3)cc1OC +CCC(C)C(NC(=O)c1ccccc1)C(=O)Nc1ncccc1C +CC(Cc1ccc2ccccc2c1)NC(=O)NCCn1ccnn1 +COc1cccc(CC(=O)Oc2ccc(C#N)cc2)c1 +Cc1nnc(SCc2cccc(C(=O)OC(C)C)c2)n(N)c1=O +COCc1ccccc1CNC(=O)C1CCN(S(N)(=O)=O)CC1 +O=C1CC2(CCN(c3nccs3)C2)CN1c1ccccc1 +CC(NC(=O)c1cccc(-n2cccc2)c1)c1nnc2ccccn12 +NC(=O)C1Cc2ccccc2CN1C(=O)c1cccnc1 +CC1(O)CCC2C3CCC4CC(O)C5CC4(CO5)C3CCC21C +COc1ccc(F)cc1NC(=O)CCn1ccc2ccccc21 +CC(NC(=O)c1ccc(F)cc1F)c1cnn(C)c1 +Cc1cc(C)nc(NCC(C)Cn2nc(C)cc2C)n1 +Cc1cc(=O)[nH]c2cc(NC(=O)c3ccccc3)ccc12 +COC(C)C(=O)N(C)c1ccc(Br)cc1F +CC1CN(C(=O)C2CCN(C(=O)N3CCCC3)CC2)c2ccccc21 +CNC(=O)c1cccc(NCC(=O)Nc2ccc(OC)cc2)c1 +CCn1cc(-c2ccc(C)cc2)cc1C(=O)N(C)C +CN(C)C1CN(Cc2ccoc2)C2CCCOC12 +COC(=O)c1cc(C)nc2onc(-c3ccccc3)c12 +O=C(NCC(O)COc1ccc(F)cc1)C1(c2ccc(F)cc2)CC1 +Cc1nnc(SC2CCCN(c3ccc(C#N)cc3)C2=O)s1 +CCNS(=O)(=O)c1ccc(C(=O)OCC(F)(F)F)cc1 +CCCN(CC(=O)N(C)C)C(=O)c1ccc(O)cc1 +CC(C)NC(=O)c1nc2c(c(=O)n(C)c(=O)n2C)n1C +CC(C)C(=O)N1CCCN(S(=O)(=O)CCc2ccccc2)CC1 +O=C(Nc1ccc2c(c1)OCCCO2)c1cccc2c1OCO2 +CC1CN(c2cc(NCCO)ncn2)CCC1(O)C1CCOCC1 +C#CCn1cnc2c(cnn2-c2cccc(C)c2C)c1=O +COCC(=O)NC(CC(=O)OC)c1ccc(C)cc1 +Cc1cccc(NC(=O)c2ccc(S(=O)C(C)C)cc2)c1 +Cc1cnn(C2CCCN(C(=O)C3CCc4ccccc43)C2)c1 +COC(=O)c1ccccc1NC(=O)c1ccc(-n2nncc2C)cc1 +OC(COc1ccc(Cl)cc1)CN1CCOC(c2ccccc2)C1 +Cc1cc(C(=O)N2CCN(c3ccc(F)cc3)CC2)c2ccccc2n1 +CC(C)CCNC(=O)C(C)Oc1ccccc1N +C=CCNC(c1c(C)nn(-c2ccccc2)c1C)C(F)(F)F +CCOC(=O)CC(C)CNC(=O)N1CCCC(C)(CO)C1 +O=C(NC(CO)CO)c1coc(COc2cccc3cccnc23)n1 +CSc1ccccc1NC(=O)c1ccc(N2CCCC2)nn1 +CC(Sc1nnnn1C)C(=O)N(C)c1ccccc1 +C=CCNC(=O)c1ccc(NC(=O)COC2CCCCC2)cc1 +N#Cc1nc(-c2cccs2)oc1NCCCN1CCOCC1 +Cc1cc(C(=O)N(Cc2cnc3ccccn23)c2ccccc2)no1 +CCCn1cc(NC(=O)Cc2ccc(C(F)(F)F)cc2)ccc1=O +CCn1cnc2ncnc(SCc3ccccc3)c21 +COC(Cc1ccc2c(c1)NC(=O)CCO2)(OC)OC +CC(C)CC(=O)NCCCn1nc2ccccn2c1=O +CCOc1ccc(C)cc1-c1cn2ccc(CO)cc2n1 +CC(=O)c1c(F)cccc1N1CCCC(N2CCNC2=O)C1 +CCOC(=O)N1CCN(C(=O)Nc2ccc(Cl)c(Cl)c2)CC1 +O=C(c1nnsc1-c1ccc(Cl)cc1)N1CCOCC1 +CCc1ccc(C(=O)N2CCCCC2CNS(C)(=O)=O)cc1 +O=C(C1COc2ccccc2O1)N1CCN(Cc2ccsc2)CC1 +O=C(NCc1nnc2n1CCC2)c1cc(Cl)ccc1F +O=C(CNc1cccc(F)c1)NCC(O)c1ccc(Cl)cc1 +Cc1ccc(C(=O)NCCC2CCCO2)c(=O)[nH]1 +CCn1ccc(=O)nc1SCc1nc2ccccc2s1 +Cn1nnnc1-c1cccc(NC(=O)c2cscn2)c1 +CC(C)Nc1cc(N2CCN(c3ncccc3C#N)CC2)ncn1 +CCCCC(CC)CNC(=O)c1c[nH]c2ccccc2c1=O +Cc1cc(F)ccc1NC(=O)Cc1nnc(-c2cnccn2)o1 +CNc1nc(-c2csc(CCN3CCOCC3)n2)cs1 +CCN(CC)C(=O)C(CC(C)C)NC(=O)c1ccccc1C +CNC(=O)C1CCC(NC(=O)c2cc(C)sc2C)CC1 +CC(C)c1nc(C#N)c(NCC(c2cccs2)N2CCOCC2)o1 +CC(=O)c1cc(F)cc(Nc2ccc3c(c2)OCCO3)c1 +Cc1ccccc1C(=O)N(Cc1ccc(C#N)cc1)C(C)C +CC(NCc1nnc2n1CCC2)c1ccc(SC(F)F)cc1 +COc1ccc(OCCNc2ccc(F)c(C(N)=O)c2)cc1 +COC(=O)c1cccc(NC(=O)N2CCOCC2)c1 +Cc1ccc(C(=O)N2CCC3(CC(=O)N(c4cncnc4)C3)C2)o1 +Cc1ccc(Oc2ccc(C(=O)Nc3cc(C)on3)cc2)nn1 +O=C(Cc1cnc(-c2ccccc2F)s1)Nc1nccs1 +CCOC(=O)N1CCCC(C(=O)Nc2nc3ccc(C)cc3s2)C1 +Cc1cccc(CCNC(=O)N(C)CC2CCCO2)c1 +CC(NC(=O)c1cccc(-c2ccoc2)c1)c1ccco1 +COc1ccc(Cc2nc(CCO)cs2)cc1C +CC(=O)NC(C)C(=O)OCC(=O)Nc1ccc(C(F)(F)F)cc1 +CCc1n[nH]c(C2CCN(C(=O)OC(C)(C)C)CC2)n1 +CNC(=O)c1ccc(NC(=O)C(C)n2cnc3ccccc32)cc1 +CC(C)C(C(=O)OCC1CC(=O)N(C2CC2)C1)N1CCCC1=O +CC(C)NC(=O)N1CCOC2(CCCN(c3cccc(F)c3)C2)C1 +Cc1nc(COc2ccc(C(=O)N(C)C3CCCCCC3)cc2)no1 +Cn1c(N2CCCC(C(=O)NCc3ccco3)C2)cc(=O)n(C)c1=O +CCN(Cc1ccc2c(c1)OCO2)C(=O)CCC(C)C +COC(=O)C1=C(C)C(C(=O)COC(=O)c2ccccc2Cl)=NC1C +Cn1c(C(N)=O)cnc1Sc1ncc(C(F)(F)F)cc1Cl +CCCCOCC(O)Cn1c(C)nc2ccccc21 +CC(=O)Nc1cc(NCC2=Cc3ccccc3OC2)ccc1F +NC(=O)c1nn(-c2cccc(C(F)(F)F)c2)c(=O)cc1O +CC(=O)N1CCC(Cc2cccc(Nc3cnccn3)n2)CC1 +CCNC(=O)CSc1ccccc1S(C)(=O)=O +Cc1ccccc1OCC(=O)NCCc1nnc2n1CCCCC2 +Cc1cccc(NCC(=O)N2CCc3ccccc32)c1C(N)=O +CC(C)N(CCCO)C(=O)c1c(F)cccc1Cl +Oc1cc2c(cc1C(F)(F)F)CCNC2c1cncnc1 +CC(C)CCCCNC(=O)NC(C)c1ccc2c(c1)NC(=O)CO2 +COC(=O)c1sc2nc(-c3ccc(OC)cc3)[nH]c(=O)c2c1C +CN(C(=O)c1cccc(S(=O)(=O)N(C)C)c1)c1ccccc1 +COCCOCCNC(=O)Nc1cc(C)cc(C)c1 +COc1ccccc1CNC(=O)c1nnn(-c2ccc(F)cc2)c1N +Cc1cccc(NCC(=O)N2CCCC(C(N)=O)C2)c1C +O=C(Nc1ccc(N2CCNC2=O)cc1)C1CC2CCC1O2 +CCn1nnc2c(NCc3ccc(F)cc3)ncnc21 +CCC1CN(C(=O)Cc2c(C)nc(C)[nH]c2=O)CC1N1CCOCC1 +O=C(CCc1ccco1)Nc1ccc2c(c1)CCC2 +CCCCC(NC(N)=O)C(=O)N(C)Cc1ccoc1C +O=C(Nc1nc(-c2cccc(Cl)c2)ns1)c1cnns1 +Cc1ccnc(N2CCCC(C(=O)NCCc3ccco3)C2)n1 +O=S(=O)(c1cccc2nonc12)n1cc(Cl)cn1 +Cn1cc(CCNC(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1 +CC(CO)NC(=O)Nc1ccc(C(=O)NC2CCCCC2)cc1 +COC(=O)c1sccc1S(=O)(=O)NC1CCCC(O)C1 +CC(C)(C)OC(=O)N1CCCCC1CNc1nccs1 +O=C(Cc1noc2ccccc12)Nc1ccc(N2CCNC2=O)cc1 +Cc1cccc(NC(=O)Cn2c(=O)n(C)c3ccccc32)c1 +Cc1nc2nc(COc3ccccc3)nn2c(C)c1Cl +COCC1(C(=O)NCc2cccnc2Oc2ccc(C)nc2)CCC1 +CCOc1cccc(C(C#N)N(C)C(=O)c2ccccc2C)c1 +CCOC(=O)Cc1ccc(N2Cc3ncccc3C2=O)cc1 +CC(=O)NCc1ccc(C(=O)N(C)CCC#N)cc1 +Fc1ccccc1N1CCN(c2nccc(-c3ccncc3)n2)CC1 +CCNc1ncc(C(=O)NCC(C)N(C)c2ccccc2)cn1 +CC(C)n1ccc(C(=O)Nc2ccc(C#N)cc2)n1 +COc1cc2c(cc1OC)CN(C(=O)CNc1ccc(C)cc1)CC2 +COc1ccc(Cl)cc1NC(=O)N1CCC(C)CC1 +c1cncc(CNc2ncc(-c3cnccn3)c(-c3ccoc3)n2)c1 +CCC(=O)N1CCN(c2ccc(Cl)cc2C)C(=O)C1C +CCOc1ccc2c(C(=O)NCCCO)cc(=O)oc2c1 +CC(C)(C)Oc1cc(CNC(=O)NCc2cscn2)ccn1 +Cc1cc(NC(=O)c2csc(CC(C)C)n2)n(C)n1 +CC(=O)NCC1CN(c2ccc3c(Cl)ccnc3c2F)CCO1 +O=c1c2nnc3ncnn3c2ccn1Cc1ccccn1 +N#Cc1cccc(CSc2n[nH]c(=O)n2CCc2ccccc2)c1 +Cc1ccc2nc(C(=O)NCc3ccccc3C)cn2c1 +O=C(Cn1c(-c2cccs2)cc2ccccc21)NC1CC1 +O=C(CSc1n[nH]c(=O)n1-c1cccnc1)N1CCOCC1 +CCNC(=O)CN(C)S(=O)(=O)c1cccc(C(C)=O)c1 +CCC(C)NC(=O)c1ccc(NC(=O)NCc2ccco2)c(C)c1 +COc1c(F)cc(NC(=O)C2COc3ccccc3O2)cc1F +Cc1nsc(NCC2CCc3ccccc3N2)n1 +Cc1cc(C)c(NCc2c(C)nn(C)c2C)c(C)c1 +COCCNC(=O)c1ccccc1-c1ccccc1C(N)=O +CCCn1c(=O)n(CCC(=O)Nc2ccccc2)c2ccccc21 +Cc1ccc2nc(NC(=O)CN3CCN(CCO)CC3)sc2c1 +COc1ccc(CC(=O)c2cccnc2)cc1Br +CN(C)c1ccnc(SCC(=O)Nc2ccccc2)c1C#N +CC(C)c1noc(CCNC(=O)Nc2ccc(C#N)c(Cl)c2)n1 +COc1ccc(CNc2cccc(-n3nnnc3C)c2)c(OC)c1 +Cc1cc(Sc2cc(N)cc(S(N)(=O)=O)c2)n(C)n1 +Cc1ccc(N2CC(C(=O)NCC3(C)COC3)CCC2=O)cc1C +O=C(Oc1ccc(-c2csnn2)cc1)c1ccco1 +OCC1(NCc2cnc(C3CCCCC3)s2)CCOCC1 +CC(CC(=O)NCC(=O)Nc1ccc(Br)cc1)C1CC1 +O=C(Nc1cc(F)ccc1O)c1ccc2nncn2c1 +COc1ccc(C(C)(O)CN(C)c2ccccc2)cc1OC +Cn1nc2c(c1NC(=O)c1cc(Cl)c[nH]1)CCC2 +O=C(CNC(=O)NC1CC1)NC1CC1c1cccc(F)c1 +COc1ccc(CNC(=O)N2CCCCCC2)cc1F +CCCCNC(=O)c1cnc(SC)n1-c1ccc(F)cc1 +N#CCCSc1ccccc1NC(=O)Cc1ccc(F)cc1F +CN(C)S(=O)(=O)NC(c1ccc(Cl)cc1)c1cccs1 +COc1cc(C)c(C(=O)NC(C)(C)c2ncc(C)s2)cc1OC +CC(=O)NC(C(=O)NCCNC(=O)c1ccc(F)cc1)C(C)C +N#CCCCn1nc(C#N)cc1-c1ccc2c(c1)CCCC2 +CCc1cc(=O)n2c(n1)SCC2CC(=O)NCc1ccc(F)cc1 +CCCS(=O)(=O)N1CCCCC1C(=O)Oc1ccccc1C +NC(=O)CN(Cc1ccccc1)C(=O)c1cc(=O)c2ccccc2o1 +CC(C(=O)Nc1ccc(C(N)=O)cc1)n1nnc(-c2ccccc2)n1 +COc1ccccc1C(=O)Nc1ccc(C)c(-n2cnnn2)c1 +COC(=O)c1ccc(NCc2csc(C)n2)cc1 +CCn1ccc(=O)c2cc(Br)ccc21 +Cc1ccnn1CC(C)CNC(=O)NC1CCCCC1 +Cc1noc(C2CCCN(Cc3cc(C#N)cs3)C2)n1 +CC(=O)N1CCCC(S(=O)(=O)N2CCc3ccccc32)C1 +CCOc1cc(NCCc2ccccc2)nc(C2CC2)n1 +Cn1cc(CCC(=O)NC2CC2c2cccc(Cl)c2)cn1 +COCc1ccc(C(=O)OCc2csc(-c3ccccn3)n2)o1 +O=C(c1csc(-c2cccs2)n1)N1CCCn2cncc2C1 +CS(=O)(=O)c1ccccc1C(=O)Nc1ccc2scnc2c1 +Cc1nc(CN2CCN(S(=O)(=O)c3cnn(C)c3)CC2)cs1 +Fc1cccc(CN2CC3CN(Cc4cccnc4)CCOC3C2)c1 +CC(C)N1CCOC(CC(=O)NCc2ccc3c(c2)CCCC3)C1 +CCCCS(=O)(=O)NC(C#N)c1cccc(Cl)c1 +CCNC(=O)c1cc(S(=O)(=O)NCc2ccco2)ccc1C +O=C(Nc1ccccc1F)N1CCN(C(=O)c2ccoc2)CC1 +CCOc1c(Cl)cccc1NC(=O)N(CC)CCO +Cc1n[nH]c2ncc(C(=O)Nc3ccccc3OC(F)F)cc12 +CC(c1ccccc1)N(C)C(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 +Cc1cccnc1NC(=O)Cc1ccccc1Cl +O=C(C1COc2ccccc2O1)N1CCC(c2ccc(O)cc2)CC1 +COc1ccc(CNC(=O)NC2CCN(S(C)(=O)=O)CC2)cc1 +Cc1cc(CCNC(=O)C2COc3ccccc3O2)on1 +CC1Cn2c(nnc2-c2ccc(Cl)cc2)S1 +COc1ccc(N)cc1CNc1nccnc1C#N +CCOc1c(OC)cc(CNc2ncccc2F)cc1OC +Cc1cc(NC(=O)CSc2ccccc2Cl)ccn1 +O=C(CN1CCOCC1C1CC1)NCC1Cc2ccccc2O1 +COc1ccccc1NC(=O)CSc1nnc(C(C)C)o1 +COC(=O)c1sc(NC(=O)CCc2cccc(OC)c2)nc1C +COc1ccc(-c2ccc(C(O)CN3CCOCC3)cc2)cc1Cl +COC(=O)C1(NS(=O)(=O)c2cnn(C)c2)CCCCC1 +COc1ccc(C(=O)c2ccc(O)c(Cl)c2)cc1OC +Nc1cccc(-c2nc(CCNc3cccc(F)c3)n[nH]2)c1 +Cc1cnc2nc(C)n(-c3c(C)cccc3C)c(N)c1-2 +COC(=O)c1[nH]c(C)c(C(=O)C(C)Oc2ccc(F)cc2)c1C +CC(C)COCC(C)NC(=O)c1cc(N2CCCC2=O)ccc1F +CCn1nc(C)c(CCn2ccnc2-c2ccc(F)c(OC)c2)c1C +Cc1noc(Cn2cnc3c(cnn3-c3ccccc3)c2=O)n1 +Cc1cn2cc(C(=O)NCCCc3nc(C)c(C)s3)ccc2n1 +Cc1cc(C)c(S(=O)(=O)NCCC(O)C(C)(C)C)c(C)c1 +CCCCN(C)C(=O)c1onc(-c2cccc(OC)c2)c1N +Cc1ccsc1CNCC(O)c1ccc(F)cc1F +NC(=O)CNC(=O)c1cc(C#CCO)ccc1F +O=C(NCCCO)c1cc(-c2ccncc2)nc2ccccc12 +COc1ccccc1Cn1nnc(C(=O)Nc2ccccc2)c1N +CCCN(CC(F)F)C(=O)c1cc(OC)c(OC)cc1C +COc1ccc(C(=O)Nc2cccc(S(N)(=O)=O)c2)cc1 +COC(=O)c1sccc1NS(=O)(=O)c1ccc(C)s1 +CCc1cnccc1C(=O)Nc1ccc(C(N)=O)cc1F +CCOC(C)C(=O)Nc1cc(-c2nnc3n2CCCCC3)ccc1F +Cc1cc(NC(=O)c2cnccn2)ccc1OCC(F)(F)F +O=C(Cc1c[nH]c2ccccc12)N1CCC(O)(C(F)(F)F)C1 +COc1ccc(CNc2ccccc2O)c(OC)c1 +CCC(C)CN(C)C(=O)c1cc(N2CCCC2=O)ccc1Cl +O=C(CSc1ccc(F)cc1F)NCCCO +O=C(Cn1nnc2sc3c(c2c1=O)CCCC3)c1ccccc1 +COc1ccc2c(c1)CN(C(=O)NCCc1cnn(C)c1)CC2 +CC(=O)Nc1nc(C(=O)NCCCC(C)C)cs1 +COc1cc(COC(=O)C(C)c2c(C)noc2C)ccc1C +Cc1cccc(OCC(=O)N2CCC(c3ccsc3)CC2)c1 +COC(=O)c1cccc(C(=O)OCc2nccs2)n1 +COCc1ccccc1NCC(=O)NCc1ccccc1 +CCNC(=O)c1ccc(C2CCCN2C(=O)c2cccn2C)s1 +CCC1CN(Cc2cn(CCC#N)nc2-c2ccccc2)CC(C)O1 +CC(Nc1ncccn1)c1ccc(N2CCOC2=O)cc1 +COc1ccc(-c2nc(C)nc(N3CCOCC3)c2N)cc1F +c1csc(-c2noc(-c3cc(C4CC4)[nH]n3)n2)c1 +CC(Sc1ccncc1)C(=O)N1c2ccccc2CC1C +CCc1c(C(=O)N2CCCC(CC)C2)cnn1-c1ccccc1 +CCOC(=O)C(C)NC(=O)c1ccc(OC)c(Br)c1 +Cc1noc(COC(=O)c2ncn(-c3ccccc3)n2)n1 +CC(C)(C)C(O)CN1CCN(C(=O)c2cccc(CC#N)c2)CC1 +O=C(Nc1ccc(F)cc1F)N1CCCC1CCCO +CC(C)c1nc2sc(CCc3ccccc3)nn2c1CO +O=C(C1CCCC1)N1CC(c2nc(-c3cnccn3)no2)C1 +Cc1nn(-c2ccccc2Cl)c(=O)n1CC(=O)NCc1ccoc1 +O=C(NCc1cccc(F)c1)c1cnc(C2CCCO2)s1 +COc1ccccc1N(C)CCCn1c(=O)oc2ccccc21 +CN(C)c1cccc(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)c1 +O=C(NCCCO)C1CCN(c2ncnc3[nH]cnc23)CC1 +CN(C)C(=O)CNc1ccc(-c2ccccc2)cc1 +COc1ccc(Cn2c(=O)[nH]c(=O)c3[nH]cnc32)cc1 +CC1CCc2ccccc2N1C(=O)Cn1cnc2sccc2c1=O +COc1c(O)ccc2c1C(Cc1ccc(O)cc1)NCC2 +COc1ccc(-c2nccn2Cc2cccc(O)c2)cc1OC +CC(OCC1CCN(C(=O)OC(C)(C)C)C1)c1cnccn1 +O=C(Nc1ccc2c(c1)OCCCO2)C1(c2ccccc2)CC1 +CCC1(CNC(=O)Nc2cccn(CC(F)(F)F)c2=O)CCCC1 +CCCCOc1cccc(C(=O)N2CCOCC2)c1 +Cc1cccc(-c2nc(CC(=O)NCCO)cs2)c1 +O=C(Nc1ncn(Cc2cccnc2)n1)C1CCC1 +COc1ccc2c(C(=O)NCc3ccccc3C)cc(=O)oc2c1 +O=C(Nc1c[nH]cc(Br)c1=O)c1ccnc(F)c1 +Cc1ccnc(OCC(=O)Nc2ccc(OC(F)(F)F)cc2)n1 +COC(=O)c1cnn2c1nnc1c(=O)n(-c3cccc(F)c3)ccc12 +O=C(OCc1ccccc1F)c1ccc(-n2ccnn2)cc1 +CC(=O)Nc1ccc(F)c(NC(=O)c2cc(Cl)ccn2)c1 +Cc1ncsc1C(=O)NCc1ccc(OC(C)C)c(F)c1 +CC(c1ccsc1)N1CCN(C(=O)c2scnc2C2CC2)CC1 +COc1ccc2ncnc(NCc3ccc(S(N)(=O)=O)cc3)c2c1 +N#Cc1ccc(SCC(=O)NCc2ccc(F)cc2)cc1 +CCNC(=O)Cn1c(CNC(=O)c2ccccc2)nc2ccccc21 +Cc1oc(C(C)(C)C)cc1C(=O)Nc1cccc(O)c1 +COc1cc(C)c(-c2cn3c4ccc(N)cc4nc3n2C)c(C)c1 +CN1CCN(S(=O)(=O)N2CCN(C(=O)c3ccc[nH]3)CC2)CC1 +CC(NC(=O)Cc1ccc[nH]1)C(=O)Nc1ccccc1 +Cc1noc(C)c1CCCNC(=O)c1c(C)[nH]n(CC(C)C)c1=O +COCCOc1cccc(NC(=O)NCC(C)C)c1 +Cc1ccc(C(=O)N2CCCCC2C(N)=O)cc1N +O=C(NCC1CCCCO1)NC1CCC(O)CC1 +O=C1CCCN1c1cccc(NCc2cccc3cccnc23)c1 +CCOc1ncccc1-c1nccc(CCC(F)(F)F)n1 +CCCCNC(=O)c1snc(-c2cccc(OC)c2)c1N +COc1ccc(C)cc1C(=O)Cn1cnc2ccccc2c1=O +CCOc1ccc(S(=O)(=O)Nc2ccc3oc(C)nc3c2)cc1 +O=C(NCC(=O)N(Cc1ccccc1)C1CC1)C1CCCC1 +CC(C(=O)Nc1ccccc1F)N1C(=O)c2ccccc2S1(=O)=O +Cc1cc(CN(C)C(=O)c2ccc(-c3ccsc3)nc2C)no1 +OCCn1c(CC(F)(F)F)nc2ccc(F)cc21 +Cc1ccccc1C(CC(=O)NCC1CCCC(C)C1)NC(N)=O +CCNC(=O)C(C)n1c(N)nc2cc(F)ccc21 +OCC(c1ccccc1)C1NCCc2ccc(F)cc21 +CCCn1c(C2CC(=O)N(c3ccc(F)cc3)C2)nc2ccccc21 +CCCCn1nc(CO)cc1-c1ccc(F)c(F)c1 +CC(CCCO)NC(=O)NCC(=O)N1CCN(c2ccccc2)CC1 +NC(=O)CC(c1ccc2c(c1)OCCCO2)C1CC1 +CCC1(CC)Nc2cc(Cl)ccc2N(CCC#N)C1=O +Cc1n[nH]c(C)c1CN(C)c1nc2nonc2nc1N(C)C +CCOCC1CCN(C(=O)c2ccc(OC)c(OC(F)F)c2)CC1 +Cc1ccc(-c2noc(CSc3ncc(C#N)c(N)n3)n2)cc1 +CCCS(=O)(=O)N(C)c1ccc(NC)cc1OC +Cc1noc(C(C)OC(=O)c2cccc(NC(=O)NC(C)C)c2)n1 +CCOc1ccc(NC(=O)CN(C)C(=O)OC)cc1F +Cc1cc(NCCCn2nc(C)cc2C)n2nc(C)c(C)c2n1 +CCCN(C)C(=O)NCc1ccc(C)cc1N(C)C +Cn1c(=O)cc(N2CCN(Cc3ccccc3)CC2)[nH]c1=O +N#CC(C(=O)c1ccco1)c1ncc(C(F)(F)F)cc1Cl +Cc1cccc(NC(=O)CCS(=O)(=O)c2cccc3nonc23)c1 +CCC(C)n1ncc(C(=O)Nc2ccc(C#N)cn2)c1C1CC1 +CCN1C(=O)C(O)(CC(=O)c2ccccc2)c2ccccc21 +CC(C(=O)N1CCC(OCc2ccccc2F)CC1)c1cccs1 +COCCC1CCN(C(=O)c2cccc(Cl)c2)CC1 +Cc1scc(C(=O)NCCCN2CCOCC2)c1-c1ccccc1 +CCC(=O)Nc1cccc(-c2nc3ccccc3c(=O)o2)c1 +Cn1cc(C(=O)NCCc2ccc(C(F)(F)F)cc2)cn1 +Cc1cc(=O)[nH]c2cc(NC(=O)Cn3cnc4ccccc43)ccc12 +Cc1ccnc(NC(=O)C2Cc3cc(Cl)ccc3O2)c1 +COc1cc(Br)c(CC(N)=O)cc1OC +Cc1cc2c(cc1C)OC(C(=O)NC(CCO)C(C)(C)C)C2 +Cc1nc(NC2CC2)cc(-c2ccc(Cl)cc2)n1 +CCn1cc(CN2CC3CCC2CN(Cc2ccccc2)C3)cn1 +N#CC1(NC(=O)CNc2cc(CO)ccc2Cl)CCCC1 +NC(=O)C1c2ccccc2CCN1C(=O)c1ccc(F)c(F)c1 +CCC(CC)CN1CC2OCCN(Cc3cnn(C)c3)C2C1 +CCOc1ccc(C2NC(=O)NC(C)=C2C(=O)OC)cc1Cl +CN(Cc1cccnc1)C(=O)c1cc(-c2ccccc2)no1 +O=C1CC(C(=O)N2CCCCCC2)CN1CCc1ccc(F)cc1 +O=C(NCc1ccc(-n2cccn2)cc1)c1n[nH]c(=O)[nH]1 +CCn1nc(C)c(NC(=O)NCc2ccnn2C)c1C +CCOC(=O)CCC(C)NC(=O)N1CCCC2CCCC21 +CC(=O)Nc1nc(CC(=O)Nc2cccc(Cl)c2)cs1 +COc1ccc(C)cc1NC(=O)c1ccc(OC(F)F)c(OC)c1 +CCOC(=O)c1oc2nc(C)c3c(c2c1N)CC(C)(C)OC3 +Cc1c(C(=O)Nc2nnc(C3CC3)s2)cnn1-c1ccccc1 +N#Cc1ncn(CC(=O)Nc2c(F)cc(F)cc2Br)n1 +CN1CCN(S(=O)(=O)c2ccccc2F)Cc2ccccc21 +Cc1nc(-c2ccncc2)[nH]c(=O)c1CC(=O)NC(C)c1ccccc1 +C=CCCC(=O)N1CCCC(C2(C)OCCO2)C1 +O=C(CCOc1cccn(CCO)c1=O)N1CCCCC1 +CCC(CC)NC(=O)C1CC(=O)N(c2ccc(F)c(Cl)c2)C1 +COc1ccc(Br)c(NC(=O)NCC(O)C(C)C)c1 +CS(=O)c1cccc(NC(=O)CCc2cc(Cl)cs2)c1 +C=CCOCCCC(=O)N1CCOc2ccc(F)cc21 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cccc(C#N)c1 +O=C(CSc1ccncc1)NCCc1cccc(Cl)c1 +COC(=O)c1sccc1NS(=O)(=O)c1ccc(C)c(C)c1 +CC(C)Oc1nnc(SCCn2c(=O)oc3cccnc32)s1 +CCn1cc(Cl)c(CN(C)S(=O)(=O)c2ccccc2)n1 +CC(O)CCN(C)C(=O)Nc1ccc(SC2CCCC2)cc1 +COc1cccc(C(=O)Nc2ccc(C(=O)NC(C)C)cc2)c1 +CCn1c(C(=O)N2CC(=O)Nc3ccccc32)cc2ccccc21 +CC(=O)N1CCN(CCNc2ccc(C#N)cc2F)CC1 +O=C(Cn1c(-c2ccncc2)nc2ccccc21)Nc1ccccc1F +COc1cccc(CN2CCN(C(=O)Nc3ccc(F)cc3)CC2)c1 +CCCCCNC(=O)c1nnc2n(c1=O)CCN2c1ccc(C)cc1 +CC(C)S(=O)(=O)N1CCN(c2cnccn2)CC1 +CCc1ccsc1C(=O)NCCC(=O)N(C)C +Cc1ccc(CN(C)S(=O)(=O)N2CC(C)OC(C)C2)o1 +CCNC(=O)CNC(=O)Nc1ccc(OCC)cc1 +N#CCOc1cccc(Cc2nc(CC(=O)Nc3ccccc3)no2)c1 +Cc1cc(C(=O)NCCC(=O)NCc2ccccc2)n(C)n1 +N#Cc1cccc(CNC(=O)c2cccc(C(=O)N3CCCC3)n2)c1 +CCC(C)C(=O)Nc1ccc(CCC(=O)NC(C)C)cc1 +Cc1ccc2ccccc2c1NC(=O)N(C)CC1(CO)CCC1 +CC(C)c1cc(C2CCCN2C(=O)C2CCCO2)on1 +O=C(NCc1ncc[nH]1)Nc1ccc(C(=O)NC2CCCCC2)cc1 +CN(C)C(=O)c1cc(NC(=O)NCC(C)(C)c2ccncc2)ccn1 +CCOC(=O)c1ccc(NC(=O)C2(C)CC2(Cl)Cl)c(O)c1 +CCCC1CCC(NC(=O)c2cc(C3CC3)[nH]n2)CC1 +Brc1ccc2c(c1)C(Cn1cnnn1)NCC2 +Cc1cc(C(=O)Nc2ccc3ncsc3c2)no1 +Cn1cc(CNC(=O)Nc2ccc(-n3ncc4ccccc43)cc2)cn1 +CCN(CC(C)C#N)C(=O)CNc1ccc(-c2nccc(C)n2)cc1 +CC(=O)c1c[nH]c(C(=O)NC(C)c2ccc3c(c2)NC(=O)CO3)c1 +COc1ccc(-c2noc(CN3C(=O)COc4ccccc43)n2)cc1 +COc1ccc2ccn(CC(=O)Nc3ccccc3OC)c(=O)c2c1 +CC(C)(CO)n1c(-c2ccncc2)nc2cc(N)ccc21 +O=C(CNC(=O)c1cccc(F)c1)Nc1ccc(-c2cnco2)cc1 +CCOc1ncccc1CNC(=O)NCc1ccc(C)cc1 +CNC(=O)CN1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1 +O=C(CCc1nc[nH]n1)Nc1ccccc1Nc1ccccc1 +Cc1nc(-c2cccnc2)sc1C(=O)N1CC(C)OC(C)C1 +CC1Cc2ccccc2N1C(=O)c1ccc(S(C)(=O)=O)cc1 +COc1cccc(-c2noc3c2CN(c2ccc(C)nn2)CC3)c1 +CCc1nn(C)c(OC)c1CN(C)C1CCc2ccccc2C1 +O=C(NCCCc1ccccc1)c1ncccc1O +CC1CCC(N2CC(C(=O)Nc3cnn(C)c3)CC2=O)CC1 +O=S(=O)(Oc1ccc(-n2ccnc2)cc1)c1cc(F)ccc1F +CNC(=O)c1ccc(Cl)cc1NCC(=O)Nc1cc(C)nn1C +Cc1cccc(OS(=O)(=O)c2cccc(C(=O)N(C)C)c2)c1 +COc1ccc(CNC(=O)c2ccc(Cl)cc2O)cn1 +CC=CCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CC=CC +CC(c1nnnn1-c1ccccc1)N(C)Cc1cccc(F)c1 +CCNC(=O)c1ccc(NC(=O)CCC(=O)OC)cc1 +CCN1CC(C(=O)OCc2ccc(C)c(OC)c2)CC1=O +CCCCN(C(=O)Cn1cnc2c(cnn2C)c1=O)C(C)CC +CN(CC(=O)Nc1ccccc1)c1c(F)cccc1F +CC(C)(C)NC(=O)Nc1cccc(NC(=O)C2CC2)c1 +COc1cc(OC)cc(C(=O)NCc2cccc(C(N)=O)c2)c1 +CC(=O)c1cccc(NC(=O)COc2cccc(CO)c2)c1 +COc1cc(Cl)c(C)cc1-n1nnc(CO)c1C1CCC1 +NC(=O)c1cc(Cl)ccc1OCC(=O)N1CCc2ccccc2C1 +Cc1cc(C2CCCN2C(=O)C2CCCN(S(C)(=O)=O)C2)on1 +CN(CC(O)C1CC1)C(=O)c1cc(Cl)c2c(c1)OCCO2 +CC(C)(CNC(=O)CNC(=O)c1cccs1)c1ccncc1 +C=CCC(C)(C)c1nc2cc3[nH]c(=O)[nH]c3cc2[nH]1 +CCC(=O)NC1CCN(c2cccc(F)c2)CC1 +COc1ccc(OC)c2sc(NC(=O)C3CCC3)nc12 +CCC(=O)N1CC(CC)(CC)Oc2ccc(C(C)=O)cc21 +CCC(Nc1ccc(=O)n(C)c1)c1ccc(C)cc1 +CCN(CCC#N)C(=O)CN1CC(C)OCC1C +Cc1nnsc1CNC(=O)Nc1ccc2c(c1)COC2 +Cc1ccc(C(C)NC(=O)C2COCC(=O)N2Cc2ccccc2)o1 +COCCN1CCN(c2ccc(Br)cn2)CC1 +COC(=O)c1csc(NC(=O)c2cc[nH]c2C)c1 +CCOc1cc(F)ccc1NS(=O)(=O)c1ccccc1 +CN1CCc2ccc(NC(=O)NC3(C)Cc4ccccc4C3)cc2C1=O +O=C1c2ccsc2SCCN1Cc1c(F)cccc1Cl +CNC(=O)N1CC2CC(C(=O)N3CCCC3)C(C1)O2 +COc1cn(-c2ccccc2)nc1C(=O)OCCCC#N +Cn1ccc(NC(=O)NCc2ncc(-c3ccccc3)[nH]2)n1 +Cc1cc(COC(=O)CCc2c[nH]c3ccccc23)no1 +COc1ccc(NC(=O)c2ccc(C)cc2O)cn1 +Cc1ccc(S(=O)(=O)N2CC(c3nc(C)no3)C2)cc1 +O=C(NCc1ccc(OCC(F)(F)F)nc1)c1ccc(Cl)cc1 +c1ccc(SCCCSc2ccccn2)nc1 +Cc1ccc(C(=O)Nc2ccc(CNC(N)=O)cc2)c(C)c1 +Cc1nccn1-c1ccc(C(C)Nc2ccc3nnc(C)n3n2)cc1 +CC(=O)N1CCC(Nc2nc3cc(C(F)(F)F)ccc3s2)C1 +COCC1CCCN(C(=O)c2ccc3[nH]cnc3c2)C1 +CCc1ccccc1NS(=O)(=O)c1ccc(-c2nnc(C)o2)o1 +Cn1cc(Cl)c(C(=O)NCCn2cc(Br)cn2)n1 +CCc1nc(C2CCCC2)ncc1Br +CC(C)Cc1ccc(C(=O)Cn2nc(-c3ccco3)oc2=O)cc1 +CN(Cc1nc(C(F)(F)F)cs1)C(=O)NC1CCN(C)C1=O +COC(=O)c1nc(C)c(Br)c2c(N)cccc12 +CCCNC(=O)c1cccc(NC(=O)N(C)C(C)c2cccnc2)c1 +Cc1cccc(CC(=O)OCC(=O)NCc2ccc3c(c2)OCO3)c1 +CC(C)c1noc(CCC(=O)Nc2ccc(N3CCOCC3)cn2)n1 +CC(C)(C)C(=O)Nc1ccc(F)c(C(=O)NC2(C#N)CC2)c1 +Cc1ccc(S(=O)(=O)N(C)CC(=O)OCc2ccccn2)cc1 +CC(NS(=O)(=O)c1ccccc1)c1ccc2c(c1)OCO2 +Cc1cccc(NC(=O)c2nccc3c(N)ccc(F)c23)n1 +CC(C)NS(=O)(=O)c1ccc(NCc2cn3cccnc3n2)cc1 +Cc1cc(Cl)ccc1NC(=O)COC(=O)c1ccnc(N(C)C)c1 +CC(C)(C)C(=O)CSc1nc(C2CCCC2)n[nH]1 +O=C(c1cccnc1)N1CCC2(C1)CN(C(=O)c1ccoc1)C2 +CCOC(=O)C(C)n1nnc(-c2ccc(Br)cc2)n1 +CCOCCNC(=O)NC1CCN(C(=O)c2ccccc2F)CC1 +Cc1c(NC(=O)N2CCC(c3cc[nH]n3)CC2)cnn1C +CNc1ccc(C(=O)Nc2ccc(F)cc2Cl)cc1 +COc1cccc(COc2cccc(NCc3cnnn3C)c2C)c1 +Cn1nc(C(=O)NC(C#N)c2ccc(Cl)cc2)ccc1=O +c1ccc(-n2nc(C3CCCC3)nc2CCCN2CCOCC2)nc1 +Cc1cc(NCCS(=O)(=O)N2CCc3ccccc32)nc(C)n1 +COc1ccc(CNC(=O)c2n[nH]c3ccc(C)cc23)c(OC)c1 +CCC(C)C(C)NS(=O)(=O)c1ccc(F)cc1N +CC(=O)NCCCSc1nc(N)c2c(C)c(C)sc2n1 +Cc1ccc(C(=O)N(C)Cc2c(C)noc2C)c(=O)[nH]1 +N#Cc1c(N2CCCC2)nn2c1N=CC(NC(=O)c1ccccc1)C2=O +C#Cc1cccc(NCC(=O)N2CCCc3ccccc32)c1 +CC(C)(CNC(=O)N1CCCC(c2nccs2)C1)c1ccncc1 +CCNC(=O)C1CCCN(C(=O)c2ccc(C)c(NC(C)=O)c2)C1 +FC(F)(F)CSc1nnnn1Cc1cccs1 +COc1ccc(N(C)S(=O)(=O)Cc2cccc(F)c2)cc1OC +COc1ccc(N)cc1NC(=O)c1ccc(C)c(C)c1 +O=C(Nc1ccccc1C(=O)NC1CCCC1)c1cccs1 +CC(C)CNC(=O)CN1C(=O)COc2ccc(N)cc21 +O=C(NCCC(=O)N1CCCC1)Nc1cnn(-c2ccccc2F)c1 +O=C(CCC(=O)c1cccs1)NCCc1c[nH]c2cc(F)ccc12 +CC1CCCN(S(=O)(=O)c2ccc3c(c2)NCCO3)C1 +COCc1cccc(C(=O)N(C)C(C)c2sc(C)nc2C)c1 +N#Cc1cccnc1NCC(=O)N1CCc2sccc2C1 +CSc1nc(C)c(CCC(=O)NCCCO)c(C)n1 +COc1cccc(CNC(=O)CCC(=O)c2ccc(F)cc2)c1 +COc1cccc(OC)c1C(=O)N(C)CC(C)C#N +COc1ccc(OCc2nnc(SC3CCCCC3=O)n2C)cc1 +COc1ccc(S(=O)(=O)NCC2(O)CCc3ccccc3C2)cc1 +O=C(Nc1cccc2ncccc12)c1cnc(-c2ccccc2)nc1 +CC(=O)NCCNC(=O)CSc1nc2c(c(C)c1C#N)CCC2 +CC(=O)N1CCCC1c1csc(Nc2ncccn2)n1 +CCOc1ccc(C(=O)Nc2ccc(N3CCCC3)nc2)cc1OC +O=C(Nc1cnn(CC2CCCO2)c1)c1cccc2c1OCCO2 +COCCNC(=O)c1cc(S(=O)(=O)N2CCOCC2)cn1C +CNC(=O)NCCS(=O)(=O)N1CC(C)OC(C)C1 +Cc1cc(NC(=O)NCCc2sc(C)nc2C)c2ncccc2c1 +COc1ccnc(N2CCCN(C(=O)c3sccc3OC)CC2)n1 +CCN(CC)C(=O)CN1CC(C)Sc2ccccc21 +COc1ccc(CN(C)S(=O)(=O)c2ccc(C#N)cc2)c(OC)c1 +Cn1c(SC2CCOC2=O)nc2sccc2c1=O +Cc1nc2ncnn2c(NC2CCC(=O)N(C)C2)c1C +Cc1ccn(-c2cc(O)c(-n3ccc(C)n3)cc2O)n1 +O=C(Cn1c(=O)[nH]c2c(oc3ccccc32)c1=O)Nc1ccccc1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)c1cc(C(N)=O)cs1 +O=C1CCC2(CCC(Nc3ncccn3)CC2)N1Cc1ccccc1 +CCc1ccsc1C(=O)Nc1ccc(C(=O)NC)cc1 +CCOc1ccc(C(=O)Nc2cccc(-c3nc(C)c(C)o3)c2)cn1 +Cc1ccc(CC(=O)NCCS(=O)c2ccc(Cl)cc2)cc1 +CCNc1ncc(C(=O)N(CC2CCC2)CC2CCCO2)cn1 +Fc1cc(CN2CCOC(C3CCCO3)C2)c2ncccc2c1 +Cc1noc(C(C)Sc2nc(C)c(C)c(C)c2C#N)n1 +Fc1ccc(OCc2csc(-c3ncccn3)n2)c(F)c1 +CCC(=O)N(CC(=O)NCC(=O)Nc1cccc(C)c1)C(C)C +COC(=O)c1sc(NC(=O)c2ccc(F)cc2Cl)nc1C +CC(NC(=O)C1CC1c1cccc(Br)c1)c1ccccn1 +Nc1cnc(CCc2c(F)cccc2Cl)nc1 +COCCN(CC(=O)OC)C(=O)c1cc(C)oc1C +Cc1ccc(C)c(S(=O)(=O)Nc2cc3[nH]c(=O)[nH]c3cc2C)c1 +Cc1nn(C)c(Oc2cccnc2)c1CNc1ccc(CCO)cc1 +CC(Cc1cccs1)NC(=O)NCC(C)(C)c1ccncc1 +CC(O)CN(C)C(=O)C(C)Oc1cccc(Cl)c1 +CN(C(=O)CCn1ncc(=O)c2ccccc21)C1CCCC1 +COC(=O)c1cccc(C(=O)NCc2ccccn2)n1 +CCC(C(=O)c1ccc(OC)c(N)c1)N1CCN(C(C)=O)CC1 +CCS(=O)(=O)NCC1COc2ccccc2O1 +Cc1ccc(C(C)(C)C(=O)N2CC(C(N)=O)C2)cc1 +CN(CCCNS(=O)(=O)c1cccc(C#N)c1)c1ccccc1 +CCn1nc2nc(Nc3ccc(C)c(C)c3)cc(C)n2c1=O +COc1cccc(C(=O)N2CCC(C(=O)c3ccccc3)CC2)c1O +O=C(CC1CCCCC1)N1CCN(CC2=CCCOC2)CC1 +CC(CC(=O)Nc1ccc(F)c(F)c1)n1cccn1 +O=S(=O)(Oc1ccc(-n2ccnc2)cc1)c1ccccc1Cl +CC(OCCO)C(=O)Nc1nc2ccc(N)cc2s1 +O=C(c1ccccc1)N1CCN(C(=O)c2cc(Cl)ccc2F)CC1 +COCC(C)NC(=O)c1ccccc1OCc1cscn1 +Cc1ccc(C)n1C(C)C(=O)N1CCn2c(nnc2C(C)C)C1 +Cc1cc(NCCc2cnc3ccccn23)nc(-c2cccnc2)n1 +Cn1cc(C(N)=O)cc1C(=O)Oc1ccc(NC(=O)C2CC2)cc1 +CC(C)(C)OC(=O)N1CCC(CC(=O)NCc2cn[nH]n2)CC1 +Cc1nc(SCCn2cccn2)c2c(C)c(C)sc2n1 +CNC(=O)c1ccc(OC)c(NC(=O)C2CC=CC2)c1 +COc1ccc(C(=O)N(CCc2ccccc2)Cc2ccncc2)nn1 +COCC(C)NC(=O)NC(C(=O)Nc1ccccc1)c1ccccc1 +C=CCn1c(C)cc(-c2csc(NC(=O)C3CC3)n2)c1C +CC(C)CNC(=O)NCC(=O)N1CCN(c2ccc(F)cc2)CC1 +Cc1nn(C)c2ncc(C(=O)NCc3cscn3)cc12 +COc1ccc2cc(C(=O)N3CCN(c4ncccn4)CC3)ccc2c1 +CCC(=O)NCC(=O)NC(C)c1ccc(SC)cc1 +CCC(COc1ccccc1)NC(=O)c1cn[nH]c1C +Cc1nn(C)cc1CN1CCOC(c2cccc(O)c2)C1 +COCc1cccc(NC(=O)CCc2ccco2)c1 +O=C(CCc1ccccn1)N(Cc1ccco1)Cc1cccs1 +OC1CCN(c2ccnc(-c3cccc4[nH]ccc34)n2)C1 +Cc1cc(NC(=O)c2ccccc2)ccc1S(N)(=O)=O +O=C1CN(Cc2cc(O)ccc2Br)C2CCCCC2N1 +Cc1ccncc1NC(=O)NCC(c1cccs1)N1CCOCC1 +Cc1ccc(NCC(O)c2ccco2)cc1Br +O=C1CCc2cc(C(=O)CSc3ccccn3)ccc2N1 +O=C(CCn1c(=O)oc2ccccc21)Nc1n[nH]c(-c2ccoc2)n1 +Cc1cc(C2CCC2)nc(NCCc2scnc2C)n1 +CC(C)CNC(=O)c1cc2cc(NC(=O)C3CC3)ccc2n1C +Cc1ccc(-n2nnnc2SCC(C)(C)O)cc1 +COC(=O)CCCNC(=O)C(N)c1ccc(C)cc1 +COc1ccc2nc(C(=O)NCc3cscn3)ccc2c1 +COc1ccc(C(=O)n2nc(-c3ccc(C)cc3)nc2N)cc1 +CCc1nc(NC(=O)CNC(=O)NC)sc1C +CC(C)(NC(=O)c1ccc(N2CCCC2=O)cc1)c1cccc(F)c1 +Cc1cc(C)c(NC(=O)c2ccc(N)c(F)c2)c(C)c1 +O=C(NCC#Cc1ccccc1)N1CCC(O)(C(F)(F)F)CC1 +CC(Cc1cccs1)N(C)C(=O)Cc1cccc(OCC#N)c1 +Cc1ccc(S(=O)(=O)NCc2cccs2)c(C)c1 +CCOc1ccc(C(=O)CCC(=O)N=c2sccn2C)cc1 +CCC(NC(=O)c1c(F)cccc1F)c1ccccc1 +CCOC(=O)C(CC)c1ccc2c(c1)OCCCO2 +O=C(NCCS(=O)(=O)N1CCCC1)c1cccc(-c2cn[nH]c2)c1 +CCC(CC)C(=O)NCCCc1nc2ccccc2[nH]1 +Cn1ncc2c(N3Cc4cnn(CCO)c4C3)nc(C(C)(C)C)nc21 +CC1Sc2ccc(CCOC(=O)CN)cc2NC1=O +COc1ccccc1CNc1cnn(Cc2ccccc2)c1 +CCCn1cc(C(=O)N2CCN(C(=O)N3CCOCC3)CC2)c(C)n1 +CN(Cc1cccs1)C(=O)CN1CCN(c2nccs2)CC1 +CCNC(=O)CSc1nnc(Nc2cccc(C)c2)s1 +CC(=O)N1CCCN(C(=O)c2cnc3[nH]nc(C)c3c2)CC1 +COc1ccc(C)cc1C(O)CNC(=O)c1ccccc1C +Nc1ccc(C(=O)Nc2ccc3nc(-c4ccccc4)[nH]c3c2)cc1 +CC(=O)c1cc(Cl)ccc1OCC(=O)N(C1CC1)C(C)C1CC1 +C=CCNC(=O)NCC(O)c1ccc2c(c1)CCO2 +O=C1CCC2(CCN1)CCN(c1ncc(Cl)cn1)CC2 +CC(C)C(=O)c1ccccc1NC(=O)c1cnc(C2CCCO2)s1 +Cc1cccc(C2CC2C(=O)N2CCCCC2Cn2cccn2)c1 +COCCN(C)C(=O)Nc1ccc(-n2nccc2C(F)(F)F)cc1 +CC(=O)N1CCCn2nc(C(=O)N3CCCC3C(F)(F)F)cc2C1 +O=S(=O)(Cc1noc(-c2cccs2)n1)c1ccc(F)c(F)c1 +CCC(=O)N(C)CCCOc1cccc(S(C)(=O)=O)c1 +c1cncc(-c2cn3c(n2)sc2ccccc23)c1 +CCOc1cc2c(cc1O)C(c1cnoc1C)NCC2 +Cc1cc(=O)[nH]c(SCc2oc(=O)oc2C)n1 +Cc1cc2c(o1)c1cnn(CC(=O)N3CCCC3)c(=O)c1n2C(C)C +Cc1ccc2[nH]c(=O)cc(C(=O)OCC(=O)c3ccc(F)cc3)c2c1 +CC(NC(=O)CN1CCn2c(nn(C)c2=O)C1)c1ccco1 +CCCCN(CC)C(=O)CN1CCN(C(=O)c2cccs2)CC1 +CN(Cc1nnc(-c2ccc(F)cc2)o1)Cc1nccn1C(F)F +COc1ccc(F)cc1NC(=O)c1ccc(N2CCNC2=O)cc1 +COc1ccc(NS(=O)(=O)c2cc(C)ccc2C)cc1OC +CC(C)NC(=O)CN1CCN(CC(=O)NCC2CCCCC2)CC1 +CC(C)NC(=O)C1CCN(S(C)(=O)=O)c2ccccc2O1 +CCOC(=O)c1ccc(CNC(=O)C(C)(C)C)cc1 +CCOc1ccccc1NC(=O)Cn1c(=O)cnc2ccccc21 +CC(C)c1cccc(OCC(=O)Nc2ccccc2-n2cnnn2)c1 +CN(Cc1cscn1)C(=O)c1ccc(C#CCO)s1 +N#CCOc1cccc(CC(=O)Nc2ccccc2)c1 +Cc1ccc2nc(-c3cc(N)c(C)c(N)c3)oc2c1 +CCC(=O)N1CCC(C(=O)Nc2ccc(F)cc2)CC1 +O=C(CSc1nc2ccccc2[nH]1)NC1CCOCC1 +Cc1noc(CCNC(=O)c2cc(Cl)ccc2-n2cnnn2)n1 +CCOC(=O)c1sc2ncnc(NC3CC(C)OC(C)C3)c2c1C +CCOC(=O)c1ccc(NC(=O)c2cnn(C)c2)cc1 +CC(C)(CNC(=O)Nc1ccc(F)cc1C#N)N1CCOCC1 +COCCN(C)C(=O)c1[nH]nc(C)c1Br +O=C(Nc1ccccc1S(=O)(=O)N1CCOCC1)C1CCOC1 +Cc1nc2ccccc2cc1OCC(=O)N(C)c1ccccc1 +CC1CN(C(=O)c2cnn(C3CCCCC3)c2)CC1N1CCOCC1 +Cc1nc2c(Cl)cc(C(F)(F)F)cn2c1C(C)O +Clc1ccccc1Oc1nnnn1-c1ccccc1 +Cn1cc(NC(=O)Cc2ccccc2O)cc(Br)c1=O +CC(C)(C)NC(=O)CN1CCSc2ccccc21 +Cc1cc(C)c(NC(=O)CS(=O)(=O)c2nccs2)c(C)c1 +COC(=O)c1ccc(S(=O)(=O)Nc2ccc(-n3cccn3)nc2)o1 +O=C(Nc1ccc(N2CCCC2)nc1)c1cc(-c2cccs2)n[nH]1 +COc1ccccc1OCC(=O)C(C#N)c1nc(C)cc(C)n1 +O=C(NCc1cccs1)Nc1ccc(NC(=O)C2CCCO2)cc1 +Cc1cc(CC(=O)NCCCO)ccc1OC(C)C +COC1CCN(S(=O)(=O)c2ccc(F)c(C)c2)CC1 +COc1cc(C)c(C)cc1C(O)CNc1ccccc1C#N +CC1Cc2ccccc2N1C(=O)c1cccc(S(N)(=O)=O)c1 +CN(Cc1cccs1)C(=O)CNc1ccc(C(F)(F)F)cc1 +CCN(C(=O)CNc1c(C)cc(C)cc1C)c1ccccc1 +Cc1noc(C)c1C(=O)N1CCN(C2CC2)CC1Cc1ccccc1 +CCCn1nc(C(=O)Nc2ccc(S(C)(=O)=O)cc2)ccc1=O +COCc1nc(NC(C)(C)C)cc(OCC(C)C)n1 +Cc1nccn1-c1nccnc1C1CCCN(C(=O)c2ccccc2)C1 +CCOc1ccc2c(c1)CN(C(=O)NCC(C)C)CC2 +CCC(C)NC(=O)Nc1ccc(CN2CCOC2=O)cc1 +O=C1CN(C(=O)c2csc(COc3ccc(F)cc3)n2)CCN1 +COc1ccc(CCN2CCCCS2(=O)=O)c(OC)c1 +CC(C)(C)n1nc(C(=O)NCCC(=O)N2CCCC2)cc1C1CC1 +CCc1ccc(OC(=O)CSc2ccc(NC(C)=O)cc2)cc1 +Cc1cc2ncn(CCS(=O)(=O)c3ccccc3)c2cc1C +Cc1ccc2ncc(C(=O)Nc3cccc(-n4ccnn4)c3)n2c1 +CC(NS(=O)(=O)c1cc(F)cc(F)c1)C(=O)N1CCCCC1C +CC(C)OC(=O)c1nnn(-c2cc(Cl)cc(Cl)c2)c1N +c1cc(CN2CCOC(Cn3cncn3)C2)c2c(c1)OCCO2 +Cc1ccc(CN(CCCO)C(=O)c2sccc2Cl)s1 +O=C(c1ccn[nH]1)N1C2CCC1c1cc(Cl)cnc1C2 +CCCc1cc(=O)n(CC(=O)Nc2cccc(C(F)(F)F)c2)cn1 +CC(C)CCN(C)C(=O)Cn1c(=O)[nH]c2ccccc21 +COc1ccc(CN2CCOC(c3cccs3)C2)c(OC)c1OC +CC(C)C(=O)N1CCN(C(=O)c2ccc3sncc3c2)CC1 +COCC12COCC1CN(C(=O)c1sccc1C)C2 +COCCN(Cc1ccsc1)C(=O)c1cccn(C)c1=O +Cc1csc(NC(=O)c2nn(C)c3ccc(F)cc3c2=O)n1 +N#Cc1c(NC(=O)c2ccco2)sc2c1CCCC2 +CC(=O)Oc1ccc(C(=O)NC(C)c2ccccc2)cc1 +Cn1ccc(NC(=O)CCNS(=O)(=O)c2cccs2)n1 +Cc1cc(C)cc(OCC(=O)NCc2ccccc2F)c1 +CC(C)c1ccccc1NC1CCN(C(N)=O)CC1 +CN(C)C(=O)Cn1c2c(ccc1=O)CCN(C(=O)c1ccc[nH]1)CC2 +Cc1cc(C(=O)n2nc(N)cc2C2CCOCC2)c(C)n1C(C)C +CCC(Sc1nnc(-c2ccccn2)n1N)c1ccc(F)cc1 +CC(=O)NCc1csc(C2CCN(C(=O)c3ccccc3)CC2)n1 +Cc1ccc(-c2nnc(NCCc3c[nH]c4ccccc34)[nH]c2=O)cc1 +CCn1nc(C)cc1C(=O)N(C)c1cc(Cl)ccc1OC +CC1CCc2c(sc(NC(=O)CSc3nncn3C)c2C#N)C1 +COC(=O)c1ccc(NCC(=O)NCc2ccccc2)cc1 +CN(Cc1ccccc1)C(=O)c1cc2c(c(S(N)(=O)=O)c1)CCC2 +CC(C)(C)c1nnc(NC(=O)C2(C#N)CCCC2)s1 +c1ccc(-c2noc(Nc3ccc4c(c3)OCCO4)n2)cc1 +CCc1nnc2n1CCN(C(=O)c1ccc(C(F)(F)F)nc1C)C2 +O=c1c(N2CCCC2)c(Cl)cnn1-c1ccccc1 +COc1ccc(-n2ncc3c2ncn2nc(-c4ccccc4)nc32)cc1 +COCC(=O)N1CC(N(C)Cc2cccnc2)C2OCCCC21 +CCCNC(=O)C(C)NS(=O)(=O)c1ccc(C(C)=O)cc1 +COc1ccc(C(=O)OC(C)C(O)c2ccc(OC)cc2)cc1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)Cc1cc(C)no1 +O=C(Cc1ccc[nH]1)N1CCCC(Cn2cncn2)C1 +CCOc1cccc(CNC(C)C(=O)NC(C)(C)C)c1 +COc1ccc(CCNC(=O)c2ccc(S(=O)C(C)C)cc2)cc1 +CC(C)(C)c1nnc(CNc2cc(Cl)cc(Cl)c2)o1 +CSc1ccc(NC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1 +CCCCN(CCO)C(=O)c1ccc(N2CCCS2(=O)=O)cc1 +N#Cc1cccnc1NCCc1cccc2cccnc12 +CSc1ccc(C(O)CNC(=O)c2cc(C)on2)cc1 +C=CCN(CC=C)C(=O)CNc1cccc(C)c1C +Cc1oc2ncn(C)c(=O)c2c1C(=O)NC1CCCC1 +COC(=O)c1[nH]c(C)c(CN(C)C(=O)Cc2ccccc2Cl)c1C +CC(Nc1cccc(F)n1)C(=O)N1CCCCC1C +COCC1CCCN(C(=O)CCc2ccccc2)C1 +CCOC(=O)CCC(=O)Nc1ccc(OC)c(Cl)c1 +OCc1cn(-c2ccccc2)nc1-c1ccc(Cl)cc1 +CN(CCc1ccccn1)c1ncnc2c1cnn2C +CCC(CC)C(=O)Nc1cccn(Cc2ccccc2)c1=O +CS(=O)(=O)NCCCNC(=O)N1CCCC(C(F)(F)F)C1 +NC(=O)C1CN(Cc2nnc(-c3ccco3)o2)c2ccccc21 +CCc1ccccc1OC1CN(C(=O)CC2CN(C(C)C)CCO2)C1 +CC(=O)NC(C)C(=O)Nc1nc2c(s1)CCCCC2 +CC(CCc1ccccc1)NC(=O)CSc1ncccc1C#N +CCC(Sc1nc(N)cc(=O)[nH]1)C(=O)Nc1ccc(Cl)cn1 +Cn1c(SCC(=O)NC2CCCCNC2=O)nnc1-c1ccco1 +CCc1ccc(S(=O)(=O)N2CCC(Oc3cccnn3)CC2)cc1 +CN(C(=O)CSc1nnc(-c2ccncc2)o1)c1ccccc1 +CC(c1cccnc1)N(C)C(=O)c1ccccc1C(F)(F)F +Cc1csc(=O)n1CC(=O)NCc1nc(-c2cccs2)no1 +Cc1cc(C(C)(O)CNC(=O)c2cccn2C)c(C)o1 +Cc1ccc(Cl)cc1NC(=O)c1cccc(C(N)=O)c1 +CC(NS(=O)(=O)Cc1ccccc1)c1ccc(C#N)cc1 +Cc1cccc2c(CC(=O)Nc3ccc(-c4nncn4C)cc3)c[nH]c12 +COc1cc(N2CC3CCN(Cc4ccncc4)C(=O)C3C2)ncn1 +CC(C)n1c(=O)nc2n1C(=O)N(c1ccc(F)cc1)C2 +Cc1cccc(C)c1NS(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +CCOc1ncccc1C(=O)Nc1nnc(Cc2ccccc2)s1 +COc1ccc(CC(=O)Nc2cc(C#N)ccc2C)cc1 +O=C(NCCc1cccc(O)c1)c1ccccc1F +Cc1cc(F)ccc1S(=O)(=O)NCCNC(=O)c1ccoc1 +O=C(c1ccc(=O)[nH]c1)N1CCCC1c1ccc2c(c1)OCCCO2 +Cc1cc(C)c(C(=O)N(C)Cc2ccc(F)cc2)c(=O)[nH]1 +COC(=O)C1=C(C)NC(=O)CC1C(=O)Nc1ccc(F)c(Cl)c1 +Cc1nnc(COc2ccc3c(C)ccnc3c2)o1 +Cc1ccc(NC(=O)c2ccc[nH]2)cc1C(=O)NC(C)C +Cc1nc(C2CN(Cc3ccc(F)c4cccnc34)CCO2)no1 +O=C(Nc1ccc(N2CCCCS2(=O)=O)cc1)c1ccc(F)cc1 +COc1ccc2c(c1)CC(CNC(=O)c1ccc(F)cc1)O2 +CCC1CCCCN1c1ncnc(-n2nc(C)cc2C)c1N +CCC(OC)C(=O)Nc1ccnn1Cc1ccccc1F +Cc1cn2c(CC(=O)Nc3nc4ccc(F)cc4s3)csc2n1 +C#CCOC(=O)c1cccc(NCc2c(C)noc2C)c1 +COc1c(Cl)cccc1NC(=O)C1CCCN1C(=O)c1ccco1 +CNC(=O)c1ccc(CSc2nc(C)cs2)cc1 +CC(=O)Nc1cc(NC(=O)Cc2cccc(OCC#N)c2)ccc1F +CCCNC(=O)NC1CCN(c2c(F)cccc2F)C1 +COC(=O)C(O)c1ccc(OC)c(Br)c1 +CCCc1n[nH]c(C2CN(CC=C(C)C)CCO2)n1 +N#CCCN(CCC(F)(F)F)C(=O)c1cc(-n2cccn2)ccn1 +Cc1nn(C)cc1CN(C)C(=O)c1ccc2c(c1)OCO2 +COc1ccc2[nH]cc(CCNc3ncncc3Br)c2c1 +CCCCC(=O)Nc1nonc1-c1ccc(F)cc1 +CC(C)c1cccc(N2CC(C(=O)N(C)CC(N)=O)CC2=O)c1 +O=C(NCc1ccccc1)NCC1COc2ccccc2C1 +Cc1cc(C)nc(CN(C)c2ncnc3c2c(C)nn3C)c1 +CCn1ccc(C(=O)Nc2nc(-c3cc(C)ccc3C)cs2)n1 +CC(C)c1nnc(NS(=O)(=O)c2ccccc2)s1 +CCNc1nc(SCC(N)=O)nc2sc3c(c12)CCN(C)C3 +C=CCNC(=O)Cc1cc(-c2ccccc2F)on1 +Cc1ccsc1CCNC(=O)C1CC(=O)N(Cc2ccncc2)C1 +CN(C(=O)c1c(-c2ccccn2)cnnc1N)c1ccccc1 +CN(C(=O)c1cccc2ccccc12)C1CCN(c2ccccc2)C1=O +COCC(=O)NCC(O)c1cn(C)c2ccccc12 +CCc1nc2n(n1)CCCC2NC(=O)c1[nH]nc2c1CCCC2 +COCCCNC(=O)Nc1ccc(-n2nc(C)cc2C)c(F)c1 +COc1ccc(OC)c(C(O)CCNc2ccc(C)cc2)c1 +CCC(CC)N(C)C(=O)NC(C)c1ccc(S(=O)(=O)NC)cc1 +COc1ccccc1CCNC(=O)CN1CCCCCC1=O +O=C(N(c1ccccc1)c1ccccc1)n1cncn1 +CCCc1nnc2sc(CCc3scnc3C)nn12 +Oc1ccc2c(c1Br)C(c1nc[nH]n1)NCC2 +CSc1ccc(CN(C)C(=O)c2cccc(S(C)(=O)=O)c2)cc1 +O=C(Nc1nc(C2CC2)cs1)N1CCC(Oc2cccnc2)C1 +CC(OC(=O)C1CCCCC1)C(=O)Nc1ccc(C(N)=O)cc1 +COC(=O)c1nn(C)c(C)c1NC(=O)COc1ccc(C)c(C)c1 +COC(=O)c1cc(-c2ccc(N)cc2)nc(N2CCC(C)CC2)n1 +CCCn1cc(C(=O)N(C)Cc2ccc(C)o2)c(C)n1 +CCc1nc(C(=O)NC(c2ccccc2)C(C)C(=O)OC)c[nH]1 +O=C(NCCCn1cncn1)NC(c1cccs1)C1CCCC1 +COc1ccccc1CN(C)C(=O)CN1CCN(CC(F)F)CC1 +CC(C(=O)Nc1cc(-c2c(F)cccc2F)[nH]n1)n1cccn1 +Cc1csc(CNC(=O)CC(NC(N)=O)c2ccccc2C)n1 +CC(C)CN(CC(C)C)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CCCNC(=O)c1c(O)nc2scc(C)n2c1=O +COc1ccc(CCNC(=O)C2CC(=O)N(C3CCOCC3)C2)cc1 +C#CCOc1cc(CNC(=O)N(C)CC2CCC2)ccc1OC +Cc1[nH]c(-c2ccc(Cl)cc2)cc1C(=O)N1CCC(C)CC1 +COc1cccc(C(CNC(=O)c2c(F)cccc2Cl)OC)c1 +Cc1ccc(OCC#CCNC(=O)Cc2cn(C)c3ccccc23)cn1 +CNC(=O)c1cc(NC(=O)N2CCCC2)ccc1Cl +CCC(CC)C(=O)NCCN1CCN(C(=O)c2cc(C)on2)CC1 +COc1cc(C2(C(=O)N3CCN(C)CC3C)CC2)ccc1C +COc1cccc(CN2C(=O)COc3cc(C)ccc32)c1 +Cc1nn(Cc2cccc(C#N)c2)c2c1C(CC#N)CCC2 +O=C(NCCc1ccccn1)NCc1cccc(O)c1 +O=C(NC1CCC2CCCC21)c1nc2ccccn2c1F +O=C1NC(c2ccc3c(c2)OCO3)Nc2ccccc21 +C=CCNC(=O)CSc1nnc(Nc2ccccc2)s1 +COc1cccc(C(=O)N2CCN(C(=O)C3CC=CC3)CC2)c1OC +Cc1cc2oc(=O)cc(CN3CC(C)OC(C)C3)c2cc1C +Cc1nc(CNC(=O)C(CC(C)C)N2CCCCC2=O)n[nH]1 +Cc1ccc(NC(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)c(O)c1 +CCCOc1cc(C)ccc1NCC(=O)NCC +CCOC(=O)COc1cccc(NC(=O)c2ccco2)c1 +CCOC(=O)C(C)NS(=O)(=O)c1cccs1 +N#Cc1cccn2nc(Cc3ccc(F)cc3)nc12 +O=S(=O)(NCc1cccnc1)c1ccc(C(F)(F)F)cc1 +COCC1(C(=O)N2CCC(Cc3cccc(C(N)=O)c3)C2)CCC1 +C=CCOC(=O)c1ccc(-c2ccc(OC)c(N)c2)o1 +CCCn1nnnc1NC(=O)c1cccc(OCc2ccccc2)c1 +CCOc1cc(C)c(C)cc1S(=O)(=O)N1CC(C)OC(C)C1 +COC(=O)c1cccc(COC(=O)c2cn(-c3ccccc3)nn2)c1 +CCC(=O)N1CCC(Nc2ccc(OCC(F)(F)F)nc2)CC1 +c1coc(CNc2ccc(Cn3cccn3)cc2)c1 +CC1CCCC(N(C)C(=O)CCNC(=O)c2cccs2)C1 +CC(=O)N1CCC(C(=O)N=c2sc3ccccc3n2C)CC1 +O=C(CC1Sc2ccccc2NC1=O)c1ccccc1 +O=C(Cc1ccccn1)N1CCN(C(=O)c2cc(F)ccc2F)CC1 +CCCn1nnnc1NC(=O)c1ccc(Br)cc1 +O=C(NCc1cc(Cl)c2c(c1)OCCO2)c1cc2ccccc2[nH]1 +CCOC(=O)N1CCC(OC(=O)c2cccc3cn[nH]c23)CC1 +COc1ccc(C(C)NC(=O)CCc2c(C)noc2C)cc1F +CCc1ccc(OCC(=O)N2CCOCC2)c(Br)c1 +CCOc1ccc(C(=O)Nc2ccc(OC)c(N)c2)cc1 +Cc1ccc(CNC(=O)C(C)NS(C)(=O)=O)s1 +Cc1csc(CCCNC(=O)Nc2nccn(C)c2=O)n1 +O=C1CCC2(CCCN(C(=O)c3ccncc3)CC2)N1 +CC1CCCC(C(=O)N(CCC#N)CCC(F)(F)F)C1 +Cc1ncc(CNC(=O)N2CCN(Cc3cccs3)CC2)s1 +Cc1cc(OC(C)C(=O)N2CCOCC2)ccc1Cl +CNC(=O)c1cccc(NC(=O)COc2ccc(Cl)c(C)c2)c1 +c1ccc(SCc2nnc3n2CCCCC3)cc1 +CCCOC1CCCN(c2ccc3cc[nH]c3n2)C1 +CCOc1ccc(-n2nnnc2CNC(=O)c2ccc(F)cc2)cc1 +Cc1nc(-c2ccccn2)sc1C(=O)Nc1cnc2ccccc2c1 +COc1cccc2c1OCC(NC(=O)c1cccs1)C2 +CSc1ccc(NC(=O)N(C)CCC#N)cc1F +O=C1CC2C(CC(O)C2CCC(O)CCc2ccccc2)O1 +COCc1ccc(CNS(=O)(=O)c2ccc(Cl)cc2F)cc1 +CCOc1ccc(OCC(=O)Nc2c(C)cc(C)cc2C)cc1 +COc1c(Cl)cccc1NC(=O)N(C)CC(=O)NC(C)(C)C +O=C(CSc1nc2cc(Cl)ccc2o1)Nn1cn[nH]c1=O +CCc1noc(CCCC(=O)NCc2ccco2)n1 +CC(NS(C)(=O)=O)C(=O)N1CCc2ccc(Br)cc21 +Cc1cc(C(=O)NC2(c3ccccc3)CCCC2)[nH]n1 +O=C(Nc1ccc2[nH]c(C(F)F)nc2c1)c1scnc1C1CC1 +Cc1[nH]ncc1CCCNC(=O)C1CCCN1C(=O)c1ccco1 +CCS(=O)(=O)N1CCc2onc(COc3ccccn3)c2C1 +CC(C)N(C(=O)COc1ccc(C(N)=O)cc1)C(C)C +Cc1cc(C)n(-c2cccc(NC(=O)C3CCC(=O)N3)c2)n1 +O=C(Nc1ccc(Br)cn1)c1cc2ncccn2n1 +COc1ccc(N2CCN(Cc3ccc(C)s3)CC2=O)cc1 +O=C(CCc1nc(-c2cccnc2)no1)N(Cc1ccncc1)C1CC1 +Cc1nc2ccccc2n1CC(=O)Nc1cccc(N)c1 +COc1ccc(CNC(=O)Cn2ccccc2=O)cc1 +CCc1ccc(NCC(=O)c2ccc(OC)c(OC)c2)cc1 +COc1ccc2c(c1)CC(C(=O)Nc1ccc(C(C)=O)cc1)CO2 +CC(CO)CNC(=O)NCC(C)(C)N1CCOCC1 +O=C(CNS(=O)(=O)N1CCCCCC1)OCc1ccccc1 +O=C(NC(c1cccs1)c1cccs1)c1cscn1 +CC(=O)Nc1cccc(-c2cccc3[nH]ccc23)c1 +CCCCS(=O)(=O)N1CCN(CC(=O)Nc2cc(C)on2)CC1 +NC(=O)C1(CNC(=O)CCCc2cccs2)CCOCC1 +O=C(NCCN1CCOCC1)N1CCCC1c1ccncc1 +CCC(CC)NC(=O)C1CC(=O)N(c2ccc(C)cc2C)C1 +Cn1ccc(-c2cc(C(=O)NCCCO)c3ccccn23)n1 +CC(C)CNC(=O)NCc1ccccc1N1CCCC1 +Cc1cc(NC(=O)NC2CCCC3OCCC23)c2ncccc2c1 +OCc1cn(Cc2ccccc2OC(F)F)nn1 +O=C1CSc2ccc(NC(=O)NCc3ccccn3)cc2N1 +COC(=O)C1CCN(C(=O)CCCNC(=O)C(C)(C)C)CC1 +COC(=O)C1CCC(=O)N1c1cccc(Cl)c1C +COc1ccc2c(CC(=O)Nc3ccc(OC)nc3)coc2c1 +Cc1nn(C)c2[nH]nc(NC(=O)C(C)Sc3ccccn3)c12 +CC(C)S(=O)c1ccc(C(=O)N(C)C2CCCCC2)cc1 +CC(Nc1ccc(NC(N)=O)cc1)c1ccccn1 +CS(=O)(=O)NCC1CCN(c2ccc(F)c(F)c2)C1 +CCn1ncc(CN(C)C(=O)c2cc(C(F)(F)F)n(C)n2)c1C +Cc1ccoc1C(=O)Nc1ccc(N)c(C(F)(F)F)c1 +CCOC(=O)C1=NCn2cc(Br)cc2C1 +CCCn1c(CCNC(=O)c2cc(F)cc(F)c2)nc2cccnc21 +CC1CC(C(=O)N(Cc2nnc(-c3ccc(Cl)cc3)o2)C2CC2)C1 +CN(Cc1ccccc1F)C(=O)CS(=O)(=O)c1ccccn1 +COCCn1c(C(=O)NCc2cccnc2)nc2ccccc2c1=O +Cc1cc(CNC(=O)Cn2c(C)c(C)sc2=O)ccc1F +Cn1cc(NC(=O)Cc2ccc(OC(F)F)cc2)cc(Cl)c1=O +CN(CC(=O)NCc1ccc(S(N)(=O)=O)s1)S(C)(=O)=O +O=C(NCc1cc2ccccc2[nH]1)N1CCN(Cc2ccon2)CC1 +CCOc1cccc2c1CCNC2c1cncnc1 +CCOC(=O)c1ccc2c(c1)nc(C(F)(F)F)n2N +Cc1ccc(S(=O)(=O)N(C)C2(C#N)CCN(C)CC2)cc1 +Cc1noc(C(NC(=O)CCCc2cc(F)ccc2F)C(C)C)n1 +Cc1cc(-c2ccc(C#N)c(N(C)C)n2)ccc1F +CC(CN1CCOCC1)NC(=O)NC1CC(=O)N(C(C)C)C1 +Fc1ccc(CNc2cccc3cccnc23)cc1 +NC(=O)C1CN(Cc2csc(C3CCCCC3)n2)CCO1 +CC1(C)CCCN1C(=O)CCNC(=O)c1n[nH]c2ccccc12 +COCCN(Cc1cnn(C)c1)C(=O)c1ccccc1C(C)=O +CC(=O)Nc1ccc(C(=O)Nc2ccc(-n3cnnn3)cc2)cc1 +Cc1cc(Nc2ncnc3c2CCN(C(=O)c2cc[nH]n2)C3)[nH]n1 +CCOC(=O)CN1C(=O)CS(=O)(=O)c2ccc(N)cc21 +COC(=O)C(C)NS(=O)(=O)c1cn(C)nc1N +COCC(C)Nc1cnn(Cc2ccccc2)c(=O)c1Cl +CCOC(=O)C1CCCN1S(=O)(=O)N1CCCCC1 +COC(=O)c1cc(-c2c(C)cc(C)c(Cl)c2C)nn1CCO +N#CCCCS(=O)(=O)N1CCC(OCc2ccccc2F)CC1 +CC(NS(=O)(=O)c1ccc(C#N)cc1)c1nnc2ccccn12 +CC(=O)Nc1cc(NC(=O)Cc2ccccc2C)ccc1C +C=CCn1c(=O)c2c(nc(-n3nc(CC)cc3CC)n2C)n(C)c1=O +C#CCCCOC(=O)c1cn(C)nc1-c1ccccc1Cl +Cc1cncc(C2NCCc3c(Cl)cc(F)cc32)c1 +Cc1cccc(NCC(=O)N(C)Cc2cccs2)c1C +Cc1ccc(C(C)NC(=O)c2ccc(OCC(N)=O)cc2)o1 +Cc1nc(CNC(=O)CC(NC(N)=O)c2ccccc2C)c(C)s1 +COc1cccc(C(=O)Nc2cccc(C(C)OC)c2)c1F +Cc1ccccc1SCC(=O)Nc1ccc2c(c1)OCCCO2 +Cc1ccc(OCC(=O)OCc2cccc(C(N)=O)c2)c(C)c1 +Cc1cnc(C(C)NC(=O)N2CCc3cc(F)ccc3C2)s1 +CCOc1ccccc1NC(=O)C1CC1c1ccc2c(c1)OCCO2 +Cc1nn(-c2ccccc2)c(C)c1C(=O)Nc1cc(F)cc(F)c1 +COC(=O)C(C)n1cnc2cc(C(F)(F)F)ccc21 +Cc1noc(C)c1S(=O)(=O)NCc1ccc(S(C)(=O)=O)cc1 +CC(Oc1ccccc1)C(=O)N1CCN(CCc2ccccc2)CC1 +O=C(Cc1ccccc1)NCC(=O)Nc1ccc(F)c(F)c1 +COc1cc(C(=O)Nc2cccc(SC)c2)cc(OC)c1OC +COCCC(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +CC(C)(C)c1cc(C(=O)Oc2cccc(C(N)=O)c2)[nH]n1 +CCOCCCC(=O)N1CCN2C(=O)CCC2C1 +CCOc1ccccc1CCN1CCCCS1(=O)=O +C=CCNC(=O)c1ccccc1NCC(=O)N1CCCCC1 +CC(C)c1ccc(OCC(=O)NC2(C#N)CCC2)cc1 +Cc1cc(CNS(=O)(=O)c2cnc3c(c2)c(C)nn3C)on1 +Cn1cc(NC(=O)Nc2ccc(OCC(F)(F)C(F)F)nc2)cn1 +CNC(=O)C1CN(C(=O)Cc2cccc(C)c2)CCO1 +CC(C)c1ccccc1C(O)CNC(=O)c1ccccc1 +CC(=O)Nc1nc(C(=O)Nc2cccc(N3CCNC3=O)c2)cs1 +COc1cc(C(=O)Nc2cccc(F)c2C#N)cc(OC)c1OC +CCCc1noc2nc(C3CC3)cc(C(=O)N3CCN(C)CC3C)c12 +C#Cc1cccc(NC(=O)CCc2ncc(-c3ccccc3)o2)c1 +O=C(CSc1ccncc1)Nc1ccc(Br)cc1F +CCCC1CN(C(=O)c2cccc(NC(=O)NC3CC3)c2)CCO1 +O=C(COc1ccc(F)cc1)Nc1ccc(Br)cn1 +Cn1cnc2cc(C(=O)OCC(=O)N3CCCC3)ccc21 +Cc1cc(C(=O)OC(C)c2nccs2)c(C)o1 +O=S(=O)(CC1=NCCCCC1)c1ccccc1Cl +CCNC(=O)CNc1ccnc(C(=O)NCC)c1 +CCc1onc(C)c1NC(=O)N(C)CCOc1ccccc1OC +CC(C)n1cnnc1S(=O)(=O)Cc1cccc(Cl)c1 +CC(Nc1ncccc1C#N)c1ccccc1Br +Cn1nccc1C(=O)Nc1cccc(C(F)(F)F)c1 +Cc1csc2ncn(Cc3cc(-c4cccnc4)no3)c(=O)c12 +Cc1cc(C)n(CC(=O)N2CCCCC2c2nc(CC(C)C)no2)n1 +Nc1cnc(C(F)(F)F)nc1CCC(F)(F)F +CCCC1CN(C(=O)c2ccc(C(=O)NC(C)(C)C)cc2)CCO1 +CS(=O)(=O)N(c1ccccc1C#N)S(C)(=O)=O +COCCC1(CO)CCCN(C(=O)Cc2c(C)n[nH]c2C)C1 +C#CCC(OC(=O)c1cc(N2CCCC2=O)ccc1Cl)C1CC1 +CN1CCOC(C(=O)NCC(O)c2cccc(OC(F)F)c2)C1 +COC(=O)c1ncn(Cc2nc(C)c3ccccc3n2)n1 +CCN(CCO)C(=O)CCCc1c[nH]c2ccccc12 +C=CCN1C(=O)C(C)(C)COc2cc(NC(=O)OC)ccc21 +Cc1cc(CNC(=O)CCC(=O)c2cccs2)cc(C)c1O +CCc1c(C)nn(C(=O)c2ccccc2OC)c1C +Cc1cc(C(=O)CSc2n[nH]c(N)n2)c(C)n1Cc1cccs1 +Nc1occ(-c2ccccc2F)c1C(=O)c1ccccn1 +CC(=O)N(C)Cc1cccc(NC(=O)c2occc2C)c1 +O=C(NCc1cccnc1)c1nc2ccccc2c(=O)[nH]1 +O=C(NCCc1cn2ccccc2n1)c1ccccc1 +c1ccc(CC2CCCN2c2ccc3nnnn3n2)cc1 +O=C(NCCC(=O)N1CCNCC1)c1ccc(F)cc1 +CCOC(=O)C1CCCCN1C(=O)c1n[nH]cc1N +Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CCC3)CC2)s1 +COc1ccc(-c2cc(CNC(=O)c3cccc(F)c3)on2)cc1 +O=C(c1ccncn1)N1CC2CCCC2(COCC2CCOCC2)C1 +Cc1ccccc1COC1CCN(C(=O)NC(C)C2CC2)CC1 +Cc1cc(C)c(CNC(=O)C2CC2c2ccco2)c(=O)[nH]1 +CCC(CC)N(C)C(=O)c1ccc(N2CCNC2=O)cc1 +Cc1cc(NC(=O)CSc2cc(Cl)ccc2Cl)[nH]n1 +CCOC(=O)NC(C(=O)c1ccccc1)n1cc(F)c(=O)[nH]c1=O +O=C(NCCn1cccn1)C1CCN(c2ccccc2)C1=O +CC(C(=O)NC1CCCC1)N1CCN(CC2=CCCOC2)CC1 +CCOc1ccccc1NC(=O)c1c(-c2cccnc2)noc1C +Cc1cc2ccccc2n1CC(=O)NCC1CC1C +CN(c1cccnc1N1CCCC1)S(=O)(=O)c1cccnc1 +Nc1nnc(SCC(=O)N2CCCc3ccccc32)n1C1CC1 +CCn1c(C)cc(=O)c2cccc(C(F)(F)F)c21 +CCOC(=O)c1c(C(F)F)oc(C(F)F)cc1=O +CCC(C(=O)NCc1cccs1)N1C(=O)CCCc2ccccc21 +CCOc1ccc(C(=O)Nc2cc(C)nn2CC)cc1OCC +Cc1cc(S(=O)(=O)NC(C)C)c(Cl)cc1Cl +O=C(NC1CCN(C(=O)NC2CCCCC2)CC1)c1ccncc1 +CC(CO)(CO)C(=O)c1ccc(C(C)(C)C)cc1 +CCOC(=O)COc1cccc(NC(=O)c2ccc(F)cc2F)c1 +COCCOc1ccc(NC(=O)NCc2ccc(C)c(F)c2)cc1 +Cc1nc2ccc(F)cc2n1Cc1cccc(C#N)c1 +CCNC(=O)c1cccc(NC(=O)NCc2ccc(C)c(F)c2)c1 +Cc1nnc(SCC(=O)c2c(C)[nH]c3ccccc23)s1 +CCCn1c(C)nnc1SC(C)C(=O)N(CC)c1ccccc1 +COC(=O)CCCCSc1nc2c3ccccc3ncn2n1 +C=CCN(Cc1ccccc1F)C(=O)CNC(=O)C1CC1 +CCC(=O)N1CCN(CC2(CN3CCOCC3)CCCCC2)CC1 +Cc1ccc(O)c(S(=O)(=O)Nc2cccc(F)c2F)c1 +CC1CCCN(C(=O)Cn2c(-c3ccccn3)noc2=O)C1 +O=C(CS(=O)(=O)c1ccccc1)Nc1cccc(Cl)c1 +CCc1cccc(OCC(=O)NCc2ccc(OC)cc2)c1 +CN(Cc1cc(Br)cs1)C(=O)Cn1cc(Cl)cn1 +CNC(=O)c1ccc(NC(=O)c2ccncc2F)cc1 +CCCNC(=O)NC1CCOc2c(Cl)cccc21 +Cc1c(C(=O)CSc2nnc(C3CC3)o2)oc2ccccc12 +N#Cc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)nc1 +CC(C)(CNC(=O)c1ccc2ccccc2n1)N1CCOCC1 +Cc1n[nH]c(C)c1CCOC(=O)c1cc(C(C)C)[nH]n1 +O=C(CCc1ccc(NCc2nc(C3CC3)no2)cc1)N1CCCC1 +CC(c1ccccn1)N(C)S(=O)(=O)c1cc(F)cc(F)c1 +CCCCOC(=O)Cn1c(=O)oc2ccc(CO)cc21 +N#Cc1cc(-c2ccco2)n(-c2ccccc2Br)n1 +CCC1CN(C(=O)CCOc2ccccc2)CCO1 +Cn1cc(C2CC2C(=O)N2CCC(c3nnc4n3CCC4)CC2)cn1 +O=C(Nc1cc(Cl)ccc1F)c1ncccc1O +Cn1ccc(NC(=O)Cc2cc(Cl)c3c(c2)OCCCO3)n1 +CC1C(=O)N(c2cccc(F)c2)CCN1S(=O)(=O)c1ccccc1 +Cc1ccc(NC(=O)C(C)n2cc(Br)cn2)cc1C +CC(C)(C)c1nc2cc(F)c(F)cc2n1CCCC#N +CC(NC(=O)CNC(N)=O)c1ccc(OC(F)F)cc1 +O=C(CCc1cnn(-c2ccccc2)c1)NCCC1CCCO1 +Cc1[nH]ccc1C(=O)NC1(C)Cc2ccccc2C1 +COc1cc(CCNC(=O)c2cccc(C(=O)N(C)C)c2)ccc1C +Cc1ccc(C(=O)N2CCc3ccccc3C2)cc1C +CCC(=O)Nc1ccnn1Cc1ccc(OC(F)(F)F)cc1 +CC(C)C(C)NC(=O)c1cccc(NC(=O)C2CC2)c1 +NC(=O)CCSc1nnc(-c2ccncc2)n1CC(F)(F)F +CCNC(=O)CCSc1nn2cnnc2s1 +CCCCn1nccc1NC(=O)c1ccc(C(=O)N(C)C)cc1 +CC(=O)C(C)Sc1nnc(-c2ccncc2)n1-c1ccc(C)cc1 +CC1Cc2cccc3c(=O)c(C(=O)Nc4ccc(Cl)cc4)cn1c23 +CCc1noc(-c2cc(Cl)ccc2NC(=O)C2CCCO2)n1 +COc1cc(OC)c(OC)cc1CN1CCOC2(CCC2)C1 +Cc1c(C(=O)Oc2cccc(-n3cccn3)c2)cnn1C +CCCC(=O)N1CCC(c2nc3ccccc3o2)CC1 +Cc1nc2c(NC(=O)COc3ccccc3C)cccn2n1 +O=C(CC1C=CCC1)NC(CC(F)(F)F)c1ccc(F)cc1 +Cc1ccc(C(=O)Nc2ccnn2C(C)C)cc1O +CC1CCCCN1C(=O)CN(C)c1ccc(C#N)cn1 +O=C(NCc1cccc(Cl)c1)c1cc(-c2cccs2)[nH]n1 +CCc1ccc(-n2c(SCC(N)=O)nnc2-c2ccoc2C)cc1 +CCS(=O)(=O)NCc1ccc(Oc2cccc(F)c2)nc1 +Cc1ccc(SCC(=O)Nc2ccnn2C(C)C2CC2)nc1 +Cc1ccc(C2Oc3c(F)cc(N)cc3N(C)C2=O)cc1 +CC(C)c1ccsc1C(=O)N1CCN(C(=O)c2ccco2)CC1 +OCCCCN1CCc2onc(-c3ccc(C(F)(F)F)cc3)c2C1 +Cc1cc(C)c(CNC(=O)c2ccc(S(N)(=O)=O)o2)c(=O)[nH]1 +Cc1cc(C)n(CCNc2nc3c(F)cc(F)cc3s2)n1 +CC(C)C(Sc1nc2ccccc2[nH]1)C(=O)NCC1CCCO1 +O=C(Nc1cc(-c2ccncc2)n[nH]1)c1ccc(Cn2cccn2)cc1 +Cc1c(C(=O)NC2CC2)cnn1-c1ccccc1C(F)(F)F +COc1ccc(O)c(C(=O)NCc2ccccc2Cn2cccn2)c1 +COc1ccccc1NC(=O)CSc1nnc(C)o1 +Cc1ccc(C)c(S(=O)(=O)NC2CCCC(O)C2)c1 +COc1ccc(Br)c(C(=O)OCC(=O)C2=NC=CC2)c1 +CNC(=O)c1c(C)nc(N)nc1COc1cc(C)cc(C)c1 +Cc1ccc(NC(=O)NCCc2ccncc2)cc1 +CCC(C)Cn1c(CNC(=O)COC)nc2ccccc21 +CCCn1nnnc1COC(=O)c1cc2ccccc2o1 +CCN(C(=O)c1scnc1C)C(C)c1ccc(F)cc1 +CCNC(=O)NC1(C(=O)NCC2Cc3ccccc3O2)CCCC1 +COc1ccc(S(=O)(=O)N(C)c2ccccn2)c2cccnc12 +Cc1ccc2ncc(C(=O)N(c3nc(C)cs3)C3CC3)n2c1 +Cc1ccc(OC(=O)COc2ccccc2C#N)c(C)c1 +CCCCOc1ccc(NC(=O)c2cnccn2)cc1 +Cc1ccc(C(C)NS(=O)(=O)N2CCCCC2)s1 +COc1ccc(-c2nc(Cn3ccc4occc4c3=O)no2)cc1 +O=C(c1cnccn1)N1CCOC2C(Oc3ncccc3F)CCC21 +FC(F)(F)C(Cl)(Br)Br +NC(=O)COc1ccc(NC(=O)c2ccoc2)cc1 +CC(C)(C)C(=O)C=c1[nH]c(=O)c(=Cc2cccnc2)s1 +CC1=C(C(=O)N(C)C)C(c2ccc(Br)cc2)NC(=O)N1 +COc1ccccc1-n1nnc(C#N)c1C1CCC1 +Cc1cc(C(=O)COC(=O)c2cc(C)n(C3CC3)c2C)c(C)s1 +CC(=O)c1cccc(NC(=O)c2nc(-n3cnnc3)ccc2Cl)c1 +Cc1ncccc1C(=O)NCCNC(=O)c1c(F)cccc1F +CC1Oc2ccccc2OC1C(=O)NCC#Cc1ccc(F)cc1 +CN(C)C(=O)NCCNC(=O)Nc1ccc2c3c(cccc13)CC2 +CC(=O)c1ccc(OC(=O)C2CC2c2ccccc2)cc1 +CC(C)(CNC(=O)c1ccc(F)cc1)NS(C)(=O)=O +Cc1ccccc1Oc1ncccc1CNC(=O)c1c[nH]c(=O)[nH]1 +O=C1CN(C(=O)CSc2ccccc2Br)CCN1 +C=CCN(CCc1ccccc1)C(=O)c1ccc(-n2ccnc2)nn1 +NC(=O)CCN(C(=O)CSc1ccncc1)c1ccccc1 +COc1cc(C#N)ccc1C1NCCc2c1ccc(C)c2O +COc1ccc(-c2nnc(CN(Cc3ccc(C)o3)C(C)C)o2)cc1 +C=CCCOC(C)C(=O)N1CCOCC1C1CC1 +Nc1ccc2nc(CC(=O)NCc3ccccc3F)oc2c1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1cc(C2CC2)[nH]n1 +COCCN(C)C(=O)NCCS(=O)(=O)c1ccccc1 +COc1ccc(Cl)cc1C1CCc2nc(N)nn2C1 +COc1ccc(CNC(=O)c2ccc(OCC(F)F)nc2)cc1 +CC1(c2ccccc2)CCC(=O)N(CC2(CO)CCC2)C1 +CCN(CC)S(=O)(=O)CC(=O)Nc1cccc(OC)c1 +CCCn1nc(C#N)cc1-c1ccc(OC)cc1C +Cn1cnc(S(=O)(=O)N2CCCC2c2cnccn2)c1 +O=C(Cc1ccc[nH]1)NCc1ccc(Oc2cccc(F)c2)nc1 +O=C(c1ccco1)N1CCOC2C(OCc3cccnc3)CCC21 +CC(CN(C)c1ccccc1)NC(=O)Cc1cccs1 +CC(C)(C)c1nnnn1CC(=O)NCc1cc(F)cc(F)c1 +Nc1ccc(Cl)c(C(=O)Nc2ccc3c(c2)OCCO3)c1 +CCOC(=O)CC1NCCc2cc(F)cc(F)c21 +CC(=O)NC1CCOc2c1cc(C)cc2C(O)c1ccco1 +CC(C)S(=O)(=O)N(Cc1ccsc1)Cc1ccco1 +O=C(Nc1cccc2ccccc12)N1CCC(CO)CC1 +CNC(=O)c1cc(NCc2ccncc2)ccc1Cl +Cc1[nH]ccc1C(=O)NCC1CCCCC1OCC(F)(F)F +CN(C)c1cncc(N2CCn3nc(C(=O)N4CCCC4)cc3C2)n1 +CC1CCN(c2cc(NC(=O)C3CCCO3)ncn2)CC1 +CN(C)C(=O)Cc1ccc(NC(=O)CCC2CCCC2)cc1 +O=S(=O)(c1cccc(Cl)c1)N1CC(OCc2ccccc2)C1 +COCCN(Cc1ccccc1)C(=O)c1cccc(OC)c1O +CC(=O)c1c(C)[nH]c(C(=O)CN2CCN(C(=O)C(C)(C)C)CC2)c1C +Nc1cc(C(O)CCN2CCc3ccccc32)ccc1F +COC(=O)N1CCC(NC(=O)Nc2ccc(C#N)cc2)CC1 +NC(=O)NCC1CCCN(C(=O)OCC(F)(F)F)C1 +CC(=O)Nc1ccc(F)c(NC(=O)NCc2cc(Cl)ccn2)c1 +CC1(C)CCC(NC(=O)C2(C)CC2(Cl)Cl)c2ccccc21 +CC(=O)c1cccc(COC(=O)c2ccncc2F)c1 +COc1ccc(-c2nnn(-c3ccccc3O)c2N)cc1 +Cc1[nH]nc(-c2ccc3c(c2)OCO3)c1NC(=O)C1CC1 +COCC1CN(Cc2cccs2)Cc2c1cnn2CC1CC1 +CC(O)CNC(=O)CSc1ccc2ccccc2c1 +Cc1cc2nccc(C3CCCN3C(=O)c3ccc(N(C)C)cc3)n2n1 +O=C(Nc1cccc(-n2cnnc2)c1)c1ccc(Cl)cc1F +CC(O)CN1CCN(C(=O)c2ccnc(Oc3ccccc3)c2)CC1 +COc1cc(C)cc2c1OC(c1ccccc1)CC2=O +Cc1ccc(NC2C(=O)Nc3ccc(F)cc32)cc1C +N#Cc1ccc(-c2noc(CCC(=O)c3ccc(F)c(F)c3)n2)nc1 +Nc1cnc2nc(-c3ccc(F)c(F)c3F)oc2c1 +Cc1cc(NC(=O)CCc2nc(-c3ccoc3)no2)c2ncccc2c1 +O=C(CCn1ncc2ccccc21)Nc1cccc(Cn2ccnc2)c1 +O=c1[nH]c(NCCCOC2CCOCC2)nc2ccccc12 +O=C(COc1ccc(F)cc1)N1CCN(CCn2cccn2)CC1 +Cc1ccc2nc(COc3ccc(C(=O)N4CCC4)cc3)cn2c1 +CCOCCOCC(=O)Nc1cc(C)ccc1F +O=C(COc1ccccc1Cl)N1CCN(c2ncccn2)CC1 +Cc1cc(Cl)ccc1OCC(=O)Nc1c(N)nc(N)n(C)c1=O +CCCc1ccc(S(=O)(=O)NCC2COc3ccccc3O2)cc1 +CC(NC(=O)CNC(=O)c1ccccc1Cl)c1ccccc1 +Cc1cccc(C(C)C)c1NC(=O)N(C)Cc1ccsc1 +CCNC(=O)Cc1ccc(NCc2ncc(CC)o2)cc1 +O=C(Nc1cccc(CS(=O)(=O)c2ccccc2)c1)C1CCCO1 +CCCn1c(=O)n(CCC(=O)NC(C)c2ccco2)c2ccccc21 +CC(=O)c1ccc(NC(=O)C2CC3CCC2O3)cc1 +COc1ccc2c(C(=O)Nc3ccon3)cc(=O)oc2c1 +O=C(C1CCCO1)N(Cc1ccco1)Cc1ccco1 +Cc1nnc(SCCCc2cc(Cl)ccc2Cl)n(N)c1=O +C#CCN1CCN(C(=O)CCn2cnc3ccccc32)CC1 +COCC(=O)Nc1nc2ccccc2nc1N1CCCC1 +COC(=O)c1ccc(Cn2ccc(C)c(C#N)c2=O)s1 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)Nc2ccc(Cl)cc2)c1C +O=C(NCCC(=O)N1CCCC1)c1cc2ccccc2cc1O +CCc1cc(N2CCc3[nH]nc(C4CCC4)c3C2)n2nccc2n1 +COC(=O)c1ccc2c(c1)CCN2C(=O)c1ccc(C)nc1C +O=C(Cn1c(=O)oc2ccc(CO)cc21)c1ccccc1 +CC(C)(C)OC(=O)N1CCCC1C(=O)NC1CCCCC1 +COc1ccc(OC)c(CCNC(=O)NCc2ccc(C#N)cc2)c1 +COc1ccc(C(C)(C)C)cc1-c1ncc(N)cn1 +Cc1ccc(N2CCN(C(=O)c3ccccc3F)CC2)c(C)c1 +COC(=O)CN(Cc1ccccc1Cl)C(=O)c1cnn(C)c1C +CCc1ccc(C(=O)CCC(=O)Nc2ccncc2)cc1 +COC(C(=O)N(C)Cc1cc(-c2ccccc2)no1)c1ccccc1 +Cc1ccccc1C(C(=O)N1CCC(O)CC1)N(C)C +O=C(NCCc1nc(C(F)(F)F)cs1)c1scnc1C1CC1 +Cc1nn(C)c(C)c1CC(=O)Oc1ccccc1Br +O=C(Nc1ccc2c(c1)COC2)NC1CCN(c2ncccc2F)C1 +O=C(NCc1ccccc1)c1ccc(-c2ccccc2)[nH]c1=O +COc1ccc(NC(=O)c2csc(-n3cccc3)n2)cc1 +CCOC(=O)CC(NC(=O)c1cccs1)c1ccc(C)cc1 +C#CCN1CCN(C(=O)NCc2ncccc2C)CC1 +Cn1cc(S(=O)(=O)N2CCC(NC(=O)c3cccnc3)CC2)cn1 +COc1ccc(-c2nnc(SCCC(N)=O)n2C)cc1 +COCCNC(=O)c1cc2cc3ccc(C)cc3nc2o1 +CC#CCSc1nnc(N2CCOCC2)n1C +CSc1ccccc1NC(=O)c1ccc2nccnc2c1 +O=C(Nc1nnc(C2CC2)s1)c1cnc(C2CCCO2)s1 +COc1ccc(CN2CCNc3ccccc32)cc1N +Cc1[nH]c(-c2ccccc2)nc1C(=O)N1CCC(CO)C(O)C1 +CC(C)C(=O)NCCNC(=O)c1cnc2c(c1)nnn2C +CC(NC(=O)NCCCn1cccn1)c1cccs1 +CS(=O)(=O)NCc1nnc(C(=O)Nc2ccc(F)cc2)s1 +N#Cc1cccnc1N1CC2CC3CC(C2)CC1C3 +CCn1c(=O)c2ccccc2n(CC(=O)Oc2ccc(C#N)cc2)c1=O +CN(CC(=O)NCc1nnc2ccccn12)S(C)(=O)=O +COCc1ccc(CNC(=O)c2csnn2)cc1 +Cc1csc(C2CCN(S(=O)(=O)Cc3ccon3)CC2)n1 +CCCCNC(=O)N1CCN(C(=O)CN2CCOCC2)CC1 +COc1cc(C(=O)Nc2ccccc2OC(F)(F)F)on1 +C=CCn1c(N(C)Cc2ccccc2)nc2c1c(=O)[nH]c(=O)n2C +O=c1oc(-c2ccco2)nn1Cc1ccc(OCC(F)(F)F)cc1 +Cc1nc2ccc(Cl)cn2c(=O)c1NC(=O)C1CC1 +NC(=O)c1ccccc1NCC(=O)N(Cc1ccccc1)C1CC1 +NC(=O)NCc1ccc(NC(=O)CCSc2ccccn2)cc1 +CC(=O)N1CCC(NC(=O)c2cccc(F)c2)CC1 +Cc1cccc(C)c1OCC(=O)NC1CCN(C(=O)CC(C)C)CC1 +Cc1cc(OCC(=O)Nc2nccs2)nc(-c2ccc(F)cc2)n1 +Cc1ccc(C(=O)C(C)Sc2cc(C)nn2C)cc1 +CC1CCCCN1C(=O)Cn1c(=O)n(C)c2ncccc21 +CCN(Cc1ccccn1)Cc1cnc2ccc(Br)cn12 +CN(Cc1ccc2c(c1)OCO2)S(=O)(=O)c1ccccc1F +Cc1cccc(-n2cnc(C(=O)NC(C)(C)C)n2)c1 +CSc1nc2nccc(-c3ccc(O)cc3)n2n1 +Cn1cccc(NC(=O)CCC(=O)c2ccc(F)c(F)c2)c1=O +COc1ccc(C2CC23N=C(c2ccccc2)OC3=O)cc1 +Cc1ccc(Cn2nnc(C(=O)Nc3cccc(C)c3C)c2N)cc1 +CC(C)(C)CCNC(=O)c1cncc(Br)c1 +Cc1nn(C)cc1-c1csc(NCCc2ccccn2)n1 +CC1=C(C(=O)N2CCCCC2)C(c2cccs2)n2ncnc2N1 +CC(NS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1)c1ccc(F)cc1 +O=C(c1cc(OCc2ccccc2)no1)N1CCCCC1CCO +CCC(=O)Nc1cccc(CS(=O)(=O)NC(C)(C)C)c1 +COC(=O)c1ccc(=O)n(Cc2coc(-c3ccc(C)cc3C)n2)c1 +CCc1ccc(N(CC(=O)N2CCCC(C)C2)S(C)(=O)=O)cc1 +CCCCN(C)c1ccc(S(=O)(=O)N2CCCC2)cn1 +Cc1cccnc1NC(=O)CN(C)C(=O)c1ccsc1 +C=C(C)CSc1nnc(NC(=O)C2CC2)s1 +Cc1cc(C(F)(F)F)cc(=O)n1C(C)C(=O)NC1CCCCC1 +Cc1cc(CNC(=O)c2scnc2C2CC2)ccc1F +CCc1ccc(C(C)NC(=O)c2ccc(S(C)(=O)=O)cc2)cc1 +CN(CC(=O)N1CCOc2ccccc21)S(C)(=O)=O +O=C(c1c[nH]c2ccccc2c1=O)N1CCC(Nc2ccccc2)C1 +CC(=O)N1CCc2ccccc2C1C(=O)NC1CCCCCC1 +Cc1ccsc1CN(Cc1nc2c(cnn2C)c(=O)[nH]1)C(C)C +Clc1ccccc1Cc1noc(CCc2ccncc2)n1 +CCc1cc(NC(=O)c2occc2-c2ccccc2)[nH]n1 +COCCCNC(=O)C(C)S(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1ccc(CNCc2cnc3[nH]nc(C)c3c2)s1 +CC(C)n1cc(C(=O)N2CCC(c3ccccc3Cl)C2)cn1 +O=C(c1cc(-c2ccco2)[nH]n1)N1CCN(C(=O)C2CCCO2)CC1 +CCC(CC)n1ccc(C(=O)N2CCC(c3noc(C)n3)CC2)n1 +CCNC(=O)C1CC(NC(=O)CO)CN1CC=Cc1ccc(F)cc1 +Cn1c(SC2CCCCC2)nnc1N1CCOCC1 +Cc1nc(Cc2nnc(SC(C)C)o2)cs1 +O=C(Cn1ccnn1)Nc1c(N2CCCC2)cccc1N1CCCC1 +CCOC(=O)CCCC(=O)c1ccccc1Cl +CCCN(C)C(=O)NC1CC(=O)N(c2ccccc2)C1 +C=C(C)CSc1nnc(-c2cccs2)n1C +Cc1cccc(C(=O)N2CCN(c3ncccn3)CC2)c1C +CNC(=O)CCN(C)C(=O)Nc1ccc(C(F)(F)F)cc1 +C=CCn1c(SCCC#N)nc2sc(C)c(C)c2c1=O +CC(=O)Nc1ccc(OC(=O)CCNC(=O)c2ccco2)cc1 +COc1ccc(C(=O)n2nc(-c3ccc(F)cc3)nc2N)cc1 +O=C(Nc1ccc(F)cc1)c1ccc2ccccc2n1 +COc1cc(OC)nc(NC(=O)Nc2cccc(Cl)c2)n1 +Cc1nn(C)c(C)c1S(=O)(=O)N1CCOCC1 +Cc1ccccc1CC(=O)NCCCn1cccn1 +Cn1cccc1C(=O)Nc1ccc2c(c1)CCC(=O)N2 +N#CC(c1ccccc1)N1CCN(C(=O)c2n[nH]c3ccccc23)CC1 +CSc1nnc(C=Cc2cccs2)c(=O)n1N +O=C(c1ccc2occc2c1)N1CCC(C(O)Cc2ccccc2)CC1 +Cc1nnc(NC(=O)N2CCN(Cc3noc(C4CC4)n3)CC2)s1 +COc1ccc(CNC(=O)COc2c(C)cccc2C)cc1 +Fc1cccc(C=Cc2nc(-c3ccncc3)no2)c1 +CCN1CCN(C(=O)CCCc2ccccc2)CCC1=O +Cc1cc(C#N)c(NC2CC2)nc1-c1ccc(F)c(F)c1 +O=C(NCC#CCOc1ccccc1Cl)c1cnccn1 +CCn1ncc(-c2ccc(C)cc2C)c(CO)c1=O +COCC(NC(=O)c1ccccc1C(=O)c1ccccc1)C(N)=O +CC(C)CNc1nnc(SCC(=O)N(C)C2CC2)s1 +CCCN1C(=O)c2ccccc2NC1(C)c1ccccc1OC +CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1ncccc1O2 +O=C(Cc1cc(F)ccc1F)NC1CCCC(C(=O)NC2CC2)C1 +O=C(Nc1ccc2nc(N3CCOCC3)sc2c1)c1cccnc1 +COc1cc(C(C)=O)ccc1OCC(=O)NC1CC1 +O=C(Nc1ccc2cn[nH]c2c1)c1ccc(C(F)(F)F)cc1 +CN(C)C(C#N)Cc1cccc(Br)c1 +COc1ccc(C(=O)Nc2cnn(-c3ccccc3F)c2)c(C)c1 +COC(=O)CNC(=O)CN1C(=O)C2CCCN2C(=O)c2ccccc21 +COC(=O)CN(C(=O)CCc1nc(C)no1)C(C)C +O=C(Nc1cc(N2CCCC2)ncn1)c1ccccn1 +CCOC(=O)c1cccnc1NCCS(N)(=O)=O +Cc1cnn(CCC(=O)Nc2ccc(NC(=O)OC(C)(C)C)nc2)c1 +COCCN(C)C(=O)C(C)Oc1cccc(C(C)C)c1 +O=C(NCCc1ccc(Cl)cc1)c1cn(-c2cccc(F)c2)nn1 +O=C(CN1CCOC(Cn2cncn2)C1)N1CCc2ccccc21 +O=C(NCc1ccncc1)c1cc(-c2ccco2)nc2ccccc12 +Cc1ccc(OC2CCN(C(=O)c3ccc(Cl)cc3)CC2)nn1 +CC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)c2c(C)noc2C)c1C +O=C(Nc1cccc2cnccc12)C1CC2CCC1O2 +COc1ccc(CC(=O)N2CCN(c3nccc(OC)n3)CC2)cc1 +CCN1CCc2c(cc(C#N)c(=O)n2CCCOC)C1 +COc1cccc2c1N(Cc1nnnn1-c1ccccc1)CCC2 +COC(=O)CNC(=O)C1CC(=O)N(c2ccc(OC)cc2OC)C1 +Cc1cc(N2CCC(O)(c3ccccn3)CC2)nc(N)n1 +CCOC(=O)CNC(=O)CSc1ccc(C)cc1 +CCN(CC)C(=O)N1CCC(C(=O)NCCc2cccc(O)c2)CC1 +Fc1ccc(Cn2cc(-c3noc(-c4ccccc4)n3)nn2)cc1 +Cc1cc(C(=O)NCc2ccc(OCC3CC3)nc2)ccc1F +COc1ccnc(NC(=O)c2ccc(C(F)(F)F)cc2)c1 +CCCn1nnnc1CN1CCC(Nc2ccccc2)C1 +Cn1c(=O)oc2cc(NC(=O)Cc3cccc(Cl)c3)ccc21 +Cc1cc(OCC(=O)Nc2cccc(N)c2)ccc1C(C)C +Cc1ccc(-c2ccc(C(=O)NC3CCCC3)c(N)n2)cc1 +O=C(NCc1cccc(CO)c1)c1cccc(O)c1 +Cc1cc(C)cc(CCNC(=O)Cn2ccc(=O)[nH]c2=O)c1 +CN(C)c1ncccc1C(=O)OCCN1CCOC1=O +COc1cc(OC)c(OC)cc1NC(=O)c1scnc1C1CC1 +Nc1ccccc1C(=O)N1CCN(c2ccccc2)CC1 +COc1cc(CNC(=O)Nc2ccc(C)cc2C)ccn1 +Cc1cc(C(=O)NCCCn2ccc3ccccc32)[nH]n1 +CCN(CC)S(=O)(=O)c1ccc(Cl)c(C(=O)N2CCCC2)c1 +CCOc1ccc(NC(=O)CNC(=O)c2ccc(F)nc2)cc1 +CN(C)C(=O)CN(C)C(=O)CCc1nc(-c2ccsc2)no1 +CN(C)C(=O)Cn1cc(C(=O)NCc2cccs2)nn1 +Cc1ccc(OCC(=O)Nc2ccccc2CO)cc1 +Oc1cccc2c1CCNC2C(O)c1ccccc1 +Cn1cc(Cl)cc1CNS(=O)(=O)c1cncc(Cl)c1 +CC(C)N(C)C(=O)Nc1cccc(-c2noc(C3CC3)n2)c1 +CC(NCC(=O)N1CCOCC1)c1ccccc1N(C)C +CCOC(=O)C(Cc1ccccc1)N(C)C(=O)c1cccc(C#N)c1 +Cc1cc(C(=O)Nc2cccc(-c3cn4c(n3)SCC4)c2)c(C)o1 +Cc1ccccc1Oc1ncccc1CNC(=O)C(C)(C)n1cccc1 +O=C(CNc1ccc(Cl)c(Br)c1)N1CCOCC1 +CCOc1ccc(NC(=O)NCCc2ccccn2)c(C)c1 +C=CCCC1NCCc2cc(Cl)cc(Cl)c21 +Nc1ccccc1C(=O)OCC(=O)Nc1ccc2c(c1)OCO2 +Cc1cc(NC(=O)COc2ccccc2)ccc1S(N)(=O)=O +CCCN(CC(F)F)C(=O)N1C(C)CCCC1C +Oc1ccc(SCc2cn3ccccc3n2)cc1 +Cc1ccc(C(C)(C)C(=O)NCCC(=O)Nc2ccncc2)cc1 +Cn1cc(C(C)(O)CNc2ncccc2C#N)cn1 +Cc1ccc(NC(=O)C(C)OCC(C)C)c2[nH]ncc12 +COC(=O)c1ccc(Cn2nc(-c3cccs3)oc2=O)o1 +O=C(Nc1nc2ccc(F)cc2s1)c1ccc2[nH]nnc2c1 +NC(=O)COc1cccc(C(=O)Nc2cc(F)ccc2Cl)c1 +O=C(Nc1cn[nH]c1)N1CCc2sccc2C1c1ccccc1 +CC(OC(=O)c1cccn1C)C(=O)Nc1cccc(Cl)c1Cl +COC(=O)CC(NC(=O)C1CC(=O)N(C)C1)c1ccccc1Cl +CC(C)c1csc(C(C#N)C(=O)CN(C)Cc2ccccc2)n1 +CN(CC1CCC1)C(=O)C1CC(=O)N(C)C1c1cccnc1 +Nc1nn(CC(F)(F)C(F)F)cc1Br +CCn1c(C2CCCN(c3ccc4ccccc4n3)C2)nn(C)c1=O +Oc1cc(F)c2c(c1)C(c1cnc3ccccc3n1)NCC2 +OC1(C(F)(F)F)CCN(Cc2cnc3ncccn23)C1 +CS(=O)(=O)N1CCN(c2ncc(Cl)cc2Cl)CC1 +Cc1cc(C(=O)NCc2nc(-c3cccs3)no2)c(C)s1 +Nc1cn2nc(-c3ccc(F)c(F)c3)sc2n1 +CCOC1CC(NC(=O)N(C)CC(C)c2nccs2)C12CCC2 +CCOc1ccc(C2=CCN(C(=O)c3c[nH]c(CC)n3)CC2)cc1 +C#CCN1CCN(C(=O)CNc2cc(OC)ccc2Cl)CC1 +O=C(NCc1cccc(Cl)c1)c1sccc1C1CC1 +CN(Cc1nnc2ccccn12)C(=O)Cc1ccc(C(F)(F)F)cc1 +CC1CCCCC1N(C)C(=O)c1ccc(O)c(Cl)c1 +CC(=O)OC1C(CO)C=CC1OC(=O)c1ccccc1 +Cn1nc(C(=O)N2CCC3(CCc4ccccc4O3)CC2)ccc1=O +Cc1ccc(-c2nnco2)cc1NC(=O)N(C)CC1CCC1 +CC(C)C(=O)N1CCN(C(=O)Cc2cccc(OC(F)F)c2)CC1 +COc1cc(Br)c(NC(=O)C2CCOC2)cc1OC +CC1CN(C(=O)CCS(=O)(=O)N(C)C)CCC1c1ccccc1 +Cc1ccccc1C(=O)N1CCOC(COc2cccc(F)c2)C1 +CCC(C)n1c(=O)[nH]c2ccc(Cl)cc2c1=O +Cc1ncc(C(=O)N2CCC(Sc3ccccc3C)CC2)s1 +Cc1cccc(OCCc2nc(CCO)c(C)o2)c1 +CS(=O)(=O)N1CCN(C(=O)c2cnc(C3CC3)[nH]c2=O)CC1 +Cc1ccccc1CCC(=O)NCCS(N)(=O)=O +O=c1oc2ccccc2n1Cc1coc(-c2cccc(F)c2)n1 +CNC(=O)c1ccccc1NC(=O)c1csc(C)n1 +CC(=O)NC(C)(C)c1noc(-c2cccc(NC(=O)NC(C)C)c2)n1 +COc1ccc(NC(=O)COc2ccc(C)cc2)cc1OC +CC(O)(CNC(=O)CCc1ccc(C#N)cc1)c1ccc(F)cc1 +COC(=O)Cn1cnc2onc(-c3ccc(F)cc3)c2c1=O +CC(OCC(O)CNC(=O)Nc1nccs1)c1ccccc1 +CCn1nccc1CNS(=O)(=O)c1ccc(OC)c(OC)c1 +C#Cc1cccc(NC(=O)CNC(=O)CNC(=O)c2cccs2)c1 +CC(C)c1ccc(SCC2(CO)COC2)cc1 +O=S(=O)(NCCCn1ccnc1)c1cn[nH]c1 +CC1CC(C)CN(c2nc3nccc(-c4ccccn4)c3c(=O)[nH]2)C1 +O=C(COc1ccc(-n2cnnn2)cc1)NCCC1CCCCC1 +COc1ccc(C)cc1-c1cn2c(N)csc2n1 +CCCNC(=O)C(C)NC(=O)c1ccc(F)cc1 +CC(=O)NC(C(=O)Nc1ccccc1Cl)C1CCCC1 +CCOc1ccnc(N2CCCN(c3nc(C4CC4)ns3)CC2)n1 +COCCn1nc(C(=O)Nc2ccc(C(C)=O)c(C)c2)ccc1=O +CCc1cnccc1C(=O)NCCNC(=O)c1n[nH]c2ccccc12 +CCOc1cccc(C(=O)Nn2c(C)nc3sccc3c2=O)c1 +CC(C)CC(NC(=O)c1cnn[nH]1)C(=O)N(C)C +Cc1ccccc1-c1noc(COC(=O)Cc2c(C)noc2C)n1 +COCCNC(=O)NCC#CCN1CCc2ccccc2C1 +Cc1cc(C)n(C(=O)c2cc(C(F)(F)F)n(C)n2)n1 +O=C(C1CC=CC1)N1CCC2(CC(Nc3ncccc3F)CO2)C1 +Nn1c(SCCOc2ccccc2F)nnc1-c1cccs1 +CCCCCC(=O)N1CCN(c2ccccc2O)CC1 +O=C(COc1ccc(Cl)cc1)Nc1nc2c(s1)CCC2 +CCn1cc(NC(=O)CCc2nc(C)c(-c3ccccc3)o2)cn1 +NS(=O)(=O)NCCNC(=O)c1ccc(Cl)cc1 +Cc1ccccc1CCNC(=O)c1cc(S(C)(=O)=O)ccc1C +COc1ccc(CC(=O)NCCc2nnc3ccccn23)cc1 +Cc1occc1C(=O)NCC(=O)NCC(C)(C)c1ccccc1F +CC(C)N(C(=O)Cn1cccc(C(F)(F)F)c1=O)C1CCOCC1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1ccc2c(c1)CCC2 +CNC(=O)Cc1cn(-c2ccccc2)nc1-c1ccc(Cl)cc1 +CC(C)(C)c1nsc(NC(=O)c2cn3cccnc3n2)n1 +CCCN(CC1COc2ccccc2O1)C(=O)Cn1cccn1 +N#CC(NC(=O)CCCOc1cccnc1)c1ccccc1Cl +O=C(c1ccccc1Nc1ccccc1)N1CCCC(O)C1 +C#Cc1cccc(NC(=O)N(C)C(C)c2ccco2)c1 +Cc1coc2c1C(NC(=O)c1ccc(F)cc1)CCC2 +CCCCNC(=O)Cn1cc(C#N)c2ccccc21 +Cc1nc2ccc(NC(=O)NCCCNS(C)(=O)=O)cc2s1 +O=C(OCc1cc(-c2ccc(F)cc2)on1)c1cnccn1 +Cc1ccc(CC(=O)Nc2ccccc2Oc2ccccc2)cn1 +Cc1ccc(C(=O)N(Cc2cccnc2)c2ccc(F)cc2)cn1 +CC(OC(=O)c1ccnc(-n2ccnc2)c1)c1nc2ccccc2n1C +Cc1ccccc1C1CN(Cc2cc[nH]n2)CCO1 +Cc1ccc(-c2nc(CN3CCOC(Cn4cncn4)C3)cs2)o1 +Cn1ccnc1C(NC(=O)CCc1cccnc1)c1ccc(F)cc1 +Cc1nc(Nc2ncnc(NCc3ccco3)c2N)sc1C +Cc1ccccc1CN(C)C(=O)c1nn(C)c(=O)c2ccccc12 +Cc1ccccc1NC(=O)c1cnc(N2CCCC2)nc1C +O=C(Cn1nc(C(F)F)cc1C(F)F)Nn1cnnc1 +O=C(Cn1c(=O)[nH]c2ccccc21)NCc1cc2ccccc2o1 +O=C(c1cn2c3c(cccc3c1=O)CC2)N1CCN2CCCC2C1 +O=C(Cn1nnc2ccccc2c1=O)NCCc1ccc(Cl)cc1 +Brc1ccc2ncnc(OCC3CCCO3)c2c1 +CC(=O)c1cccc(CN(C)Cc2ccncc2C)c1 +CCN(C(=O)COc1ccccc1N)c1ccccc1C +COc1ccc2c3c(c(=O)oc2c1)CCC1(C3)OCCO1 +CC(=O)c1cc2c(cc1NC(=O)CSc1nnc(C)n1N)OCO2 +O=C(Cn1nc(-c2cccs2)ccc1=O)NCc1ccccc1 +COC(=O)CC1CCN(C(=O)c2ccc(-n3nnnc3C)cc2)CC1 +CC(C)C(=O)Nc1ccc(C(=O)NC(C)(C)C#N)cc1 +O=C(Nc1ccc(C(F)(F)F)cn1)Oc1ccccc1 +O=C(NCc1ccc2c(c1)OCO2)c1cccn1Cc1cccnc1 +Cc1ccc(NC(=O)CCOCC(F)(F)F)cc1S(C)(=O)=O +CCOC(=O)c1ccc(NC(=O)c2ccccc2S(C)(=O)=O)cc1 +COc1cccc(C(=O)OCCCNC(C)=O)c1F +CCOc1cc(C)ccc1S(=O)(=O)NCc1ccc2c(c1)OCO2 +N#Cc1c[nH]c(C(=O)NC(CC2CCCCC2)c2ncccn2)c1 +CCN(Cc1ccccc1)C(=O)Nc1ccc(Oc2cccnc2)nc1 +CC(C)COC(=O)C(C)N1C(=O)CNc2ccccc21 +CCCc1ccc(OC(C)C(=O)N2CCNCC2)cc1 +CC1CN(C(=O)Cn2cc(NCc3ccccc3F)cn2)CC(C)O1 +CN(CCC#N)C(=O)CN1CCNc2cc(F)c(F)cc21 +CC(Cc1cccc(F)c1)C(=O)NCc1ccnn1C +Cc1ccc(OCCN(C)C(=O)NC(C)c2nncn2C)cc1 +O=C(CC1C=CCC1)N1CCC(c2c[nH]c3ccccc23)CC1 +O=C(CC1(O)C(=O)Nc2ccccc21)c1ccc(F)cc1 +N#CC1(C(=O)Oc2cccc(NC(=O)c3ccco3)c2)CCCC1 +O=C(NCCc1csc(-c2ccccc2)n1)NC1CCCNC1=O +Cn1nccc1C(=O)Nc1sc2c(c1C(N)=O)CCCCC2 +COc1ccccc1CNC(=O)CNc1ccc(C)cc1F +CCCCN(C)C(=O)CCC(O)c1ccc(F)c(F)c1 +O=C(NCc1ccc(F)cc1)Nc1cccc(F)c1 +CCCc1nnc(NC(=O)c2c(-c3ccccc3)noc2C)s1 +Cc1cc(OCC(=O)NC(C)C)c2c(C)c(C)c(=O)oc2c1 +CC(=O)Nc1cccc(C(=O)NC2CCc3ccccc32)c1 +CC1(C)CN(C(=O)Nc2ccc(CC#N)cc2)CCO1 +CCN(CC)C(=O)C(C)NS(=O)(=O)c1ccccc1F +CN(CCO)Cc1c(O)c(=O)cc(CO)n1C1CC1 +COCCCCCNC(=O)c1ccc2c(=O)n(C)c(=O)n(C)c2n1 +O=S(=O)(NCCn1ccnc1)c1cc(Cl)cc(Cl)c1 +CN(C)C(=O)CC1(CC(=O)Nc2ccc(F)cc2)CCCC1 +COc1cccc2[nH]c(-c3ccccc3)cc(=O)c12 +CN(C)c1c(Cl)cccc1NCc1cnccn1 +O=C(Nc1ccn(CC(F)F)n1)c1ccc(-n2ccnn2)cc1 +Cc1ccc(NCc2noc(-c3ccoc3)n2)cc1C(=O)NC(C)C +CN(CC1CCCC1)C(=O)c1[nH]nc(C2CC2)c1Br +CCOCCCNC(=O)c1nc(-c2cccnc2)no1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)Nc1cnn(C(C)C)c1)O2 +CC(C)OCCC(=O)Nc1cc(F)cc(N2CCCC2)c1 +Cc1ccsc1CN(C)C(=O)c1cc(S(C)(=O)=O)ccc1F +COc1cc(NS(=O)(=O)c2ccccc2)ccc1NC(C)=O +N#Cc1ccc(C(=O)Nc2cccc(Br)c2)cc1 +COC(=O)c1nonc1NCc1cc(F)cc(F)c1 +Fc1ccc(Cl)c2c1CCNC2c1cncnc1 +C#CCNC(=O)CSc1nnc(-c2cccc(Cl)c2)n1N +Cc1nn(C)c2c1C(c1ccc(F)cc1F)CC(=O)N2 +CC1(C)Cc2occc2C(NC(=O)Nc2ccccc2)C1 +Cc1cccc(OCc2c(C#N)nnn2CCO)c1C +Cc1cc2c(=O)n(CC(=O)Nc3ccc(CC#N)cc3)cnc2s1 +CC1Cc2ccccc2N1C(=O)CCn1c(=O)[nH]c(=O)c2ccccc21 +CC(C)c1nc(CNC(=O)N(C)Cc2ccc(F)cc2)cs1 +COCCNC(=O)C(C)Sc1nc2nc(C)cc(C)n2n1 +CCOC(=O)Cn1nc(C)n(-c2cccc(C(F)(F)F)c2)c1=O +N#Cc1ccccc1CSc1ncnc2ccsc12 +Cc1onc(-c2ccccc2)c1C(=O)NC(C)C1CCCO1 +CC(C)Nc1ncnc2c1CCN(C(=O)c1ccno1)CC2 +Cc1ccc(Cl)cc1-c1ccc(C(N)=O)c(N)n1 +COCCn1cnnc1SC(C)C(=O)Nc1ccc(C)cc1F +CC(C)(C)C(=O)c1ccsc1NC(=O)CCNC(=O)c1ccco1 +CC(NC(=O)COc1ccc(-n2cnnn2)cc1)c1ccc(F)cc1 +COc1ccc(-c2ccc(N)c3ccncc23)cc1 +O=C1CCCN1CC(O)CN1CC2(CCCC2)c2ccccc21 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccccc1Cl +CCCCCC(=O)Nc1ccc(S(=O)(=O)NC(C)=O)cc1 +CC(C)N(C)C(=O)CC(c1ccc(O)cc1)c1cccc(O)c1 +O=C(CN1CCCc2cc(F)ccc21)NC1CCCCNC1=O +Cc1cc(=O)c(OCC(=O)NCCc2nccs2)cn1C +Cc1noc(C2CCCN(C(=O)Cc3ccc4c(c3)CCCC4)C2)n1 +COCc1cccc(NC(=O)c2ccc(OC(F)F)cc2)c1 +COc1ccc(C(=O)OCC(=O)N(C)Cc2ccccc2)cc1 +CCOC(=O)CNC(=O)Nc1ccc2sc(NC(C)=O)nc2c1 +O=C1CN(C(=O)c2[nH]c3ccc(F)cc3c2Cl)CCN1 +O=S(=O)(Cc1c(F)cccc1Cl)N1CCCC1 +Cn1cnc(CNC(=O)N(CC2CC2)C2CCCCC2)n1 +O=C(CSc1nnc(-c2cccnc2)o1)Nc1ccc(F)cc1F +CC(=O)N1CCC(C(=O)OC2CC(C)CC(C)(C)C2)CC1 +O=C(c1cc(N2CCCC2=O)ccc1Cl)N1CC2CCCCC2C1 +CCCCOc1ncccc1CNC(=O)Nc1ccccn1 +COCc1ccccc1NC(=O)NCCc1nc2ccccc2s1 +CCCN(C(=O)c1ccc2nccnc2c1)C1Cc2ccccc2C1 +O=C(CSc1ccc(F)cc1)Nc1ccc(-c2cc[nH]n2)cc1 +O=C(NCCc1ccn(-c2ccccc2)n1)c1ccccc1F +CC(=O)Nc1ccccc1C(=O)NCc1ccc2c(c1)OCO2 +COC1CCCN(c2ccc(-c3nc(C4CC4)no3)cn2)C1 +CCCc1noc(CNc2cc(C(=O)NC)ccc2OC)n1 +CN(CCOc1cccc(F)c1)C(=O)C1CCCN1c1ncccn1 +COc1ccccc1NC(=O)CNc1ccccc1-n1cccn1 +CC(=O)NC(C)C(=O)NC(c1ccc(Cl)cc1F)C(C)C +O=C(NCCCc1nc(-c2ccncc2)no1)c1ccsc1 +COc1cc(N)ccc1-c1nnc(N2CCCCC2)s1 +CCCn1nnnc1NC(=O)COc1cccc(C)c1 +CSc1nc(C)c(CCC(=O)N(C)c2ccccc2)c(C)n1 +CC(=O)c1cc(F)ccc1OCC(=O)N(C)CC1CC1 +CC(=O)N1CCc2cc(NC(=O)C(C)Oc3ccc(F)cc3)ccc21 +Cc1csc(Cn2nc(C(C)(C)C)ccc2=O)n1 +CC(=O)c1c[nH]c(C(=O)NCc2ccc(OCC(F)(F)F)nc2)c1 +O=S(=O)(NC1CCC1)c1ccc(C#CCO)cc1 +Nc1c(C(=O)Nc2ccc(F)cc2F)oc2cccnc12 +CC(=O)Nc1cc2ccccc2cc1C(=O)OCC(=O)C(C)(C)C +Cc1ccc(NC(=O)N(C)C)c(C(=O)Nc2nnc(C3CC3)s2)c1 +COC(=O)CSc1nnc(-c2ccc(OC)c(OC)c2)o1 +CC(NC(=O)c1ccco1)C(=O)N(CCC#N)Cc1ccco1 +O=C(CNC(=O)c1ccc(Cl)cc1Cl)NCC(F)(F)F +COc1cccc(-n2c(N)c(C#N)c3c(c2=O)COC(C(C)C)C3)c1 +O=S(=O)(c1ccccc1F)N1CCCCC1c1cc[nH]n1 +CC(=O)N(c1ccc(C)cc1)c1nc(C)cc(C)c1C#N +O=C(Nc1c[nH]cc(Br)c1=O)c1ccccc1F +COCC(NC(C)c1cnc(C)s1)c1ccco1 +CC1(C2CCCN(C(=O)c3cc(F)cc4[nH]cnc34)C2)OCCO1 +O=C(CCC(=O)N1CCOCC1)NCCC1=CCCCC1 +Cc1ccc(-n2ccnc(NCCCOC(C)C)c2=O)cc1F +CC(Oc1ccccc1)C(=O)Nc1cccc2cn[nH]c12 +Cc1sc2nc3n(c(=O)c2c1C)CCC(=O)N3Cc1ccccc1 +Cc1ccc(NC(=O)Cc2noc3c(N)cc(F)cc23)nc1 +CC(C)Oc1ccc(F)cc1NC(=O)c1cc2c([nH]c1=O)CCCC2 +N#CC(c1ccc(Cl)cc1Cl)N1CCCC1 +Cc1cc(C(=O)N(CCC#N)C23CC4CC(CC(C4)C2)C3)no1 +Cn1ccnc1SCC(=O)c1ccc2c(c1)CCC2 +Cc1noc(C2CCC3(CCN(C(=O)Cc4cccs4)CC3)O2)n1 +O=C1CCN(C(=O)c2ccc3c(c2)OCCO3)CC1 +CCCCn1nnc(CO)c1COc1ccccc1Cl +Cc1csc(NC(=O)COCC2CCCO2)n1 +CCN(CCO)C(=O)Cc1csc(-c2ccccc2)n1 +CSc1cccc(C(=O)Nc2sc3c(c2C(N)=O)CCCC3)c1 +COc1ccc(NC(=O)c2ccc(C(=O)N(C)C)cc2)cc1C +COc1cc(C(C)C)ccc1C(=O)N1CCC(O)CC1 +CCCC(Nc1ncnc2c1c(C)nn2C)C(=O)OC +CNS(=O)(=O)c1ccc(C(=O)N2CCC3CCCCC3C2)cc1 +CC(C)C1Oc2cc(N)ccc2N(CC(=O)N2CCCCC2)C1=O +CCCNc1nc(-c2c3c(n[nH]c2=O)CCC3)cs1 +COCc1nc(CCOc2cccc(C)c2)sc1CC#N +CN(CCOc1ccc(F)cc1)C(=O)c1ccccn1 +CCCn1cc(C(=O)NC(CC)c2nc(C)no2)c(C)n1 +CCc1ccc(C(=O)N2CCN3C(=O)C4CCCN4C(=O)C3C2)cc1 +c1ccc2sc(SCCCN3CCOCC3)nc2c1 +O=C(C#Cc1ccccc1)NC1CCN(C(=O)Nc2ccccc2)CC1 +C#CCN1CCN(C(=O)NCc2cc(C)ccc2OC(F)F)CC1 +Cc1ccn2c(=O)c(C(=O)Nc3ccc(C(F)(F)F)cc3)cnc2c1 +O=C(NCCCN1CCCC1=O)c1nnn(-c2ccc(F)cc2)n1 +COC(=O)c1cccc(S(=O)(=O)NC2CCCOC2)c1C +Cc1cn(-c2ccccc2)nc1NC(=O)Cc1cccc(F)c1F +Cc1occc1-c1cc(NC(=O)C2CCCO2)n(CCO)n1 +N#CC(NC(=O)CCCc1ccccn1)c1ccc(F)cc1F +CCOC(=O)C1CCN(C(=O)C2(c3ccc(F)cc3)CCC2)CC1 +CC(C)CNC(=O)c1cn2c(n1)CCC(c1ccccc1)C2 +Nc1cc(F)ccc1OCC(=O)N1CCOCC1 +CN(Cc1cc(Br)cs1)C(=O)NCc1cc[nH]n1 +O=C(CSc1nc(=O)[nH]c2c1CCCC2)Nc1ccccc1 +CCc1nnc(N2CCC3(CCCN(CCO)C3=O)C2)s1 +CCc1cc(=O)[nH]c2cc(NC(=O)c3ccc4c(c3)OCO4)ccc12 +CC(NC(=O)NCc1ccc(N2CCCC2=O)cc1)c1ccncc1 +CC(NC(=O)c1ccc(Br)c(F)c1)c1ccccn1 +CCCCNC(=O)c1ccc(NCC(=O)N2CCOCC2)cc1 +CSc1ncc(C(=O)N2CCC(Cc3ccc(F)cc3)CC2)cn1 +O=c1c(=Cc2ccc(F)cc2)sc2nc3cccnc3n12 +Cc1cc(NC(=O)C2CCN(C(=O)Cc3ccc(F)cc3)CC2)no1 +CNC(=O)COc1ccc(NC(=O)C(C)CC2CCCC2)cc1 +N#Cc1cc2c(nc1Oc1ccccc1CN1CCOCC1)CCCC2 +CC(O)CN1CCN(C(=O)Cc2n[nH]c(=O)c3ccccc23)CC1 +COC(=O)c1ccccc1NC(=O)CNC(=O)c1ccccc1F +COc1ccc(Br)c(NC(=O)NCc2cccnc2)c1 +O=C(Nc1ccccc1O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +COc1cc(C(=O)Nc2cnn(CC3CC3)c2)cc(OC)c1OC +COc1ccc(C)cc1C(C)NC(=O)CNC(=O)Nc1ccccc1 +O=C(c1ccccc1Cl)N1CCCCC1CCN1CCOCC1 +CN(C(=O)C1CCN(C(=O)c2ccccc2F)CC1)c1ccccc1 +Cc1cc(COC(=O)c2cccc(OCc3csc(C)n3)c2)no1 +CCn1cc(C(=O)N2CCN(c3cccc(O)c3)CC2)cn1 +CCOc1ccc(-c2nc3cc(OC)c(OC)cc3[nH]2)cc1N +C=CCn1ccn(-c2ccc(Cl)cc2)c(=O)c1=O +Cc1nc(C(N)=O)nn1-c1c(Cl)cccc1Cl +OCCN1CCN(c2cccc(Cl)c2Cl)CC1 +CC(C)(C)CC(NC(=O)c1cnccn1)c1ccc(F)cc1 +O=C(NC1CCN(c2c(F)cccc2F)C1)C1CCCOC1 +Cc1cc(C(N)c2nc3ccccc3n2C)c2ccccc2n1 +COc1c(C)cnc(CNC(=O)c2ccc(N(C)C)c(F)c2)c1C +CC(C)(CNC(=O)c1n[nH]c(=O)[nH]1)c1cccc(Cl)c1 +N#Cc1cccc(C(=O)N2CCC3(CC2)CN(CC2CC2)C3=O)c1 +O=C(OCC(=O)c1c[nH]c2ccccc12)c1ccc2c(c1)OCO2 +N#CC(NS(=O)(=O)c1ccccc1)c1cccc(Cl)c1 +O=S(=O)(NCc1ccccc1)c1cccc(O)c1 +OCC1CN(c2ccc(Cl)cc2)C(c2cccs2)O1 +COC(C(=O)OCc1ccc(F)cc1)c1ccccc1 +CCc1noc(CN(C)C(=O)c2cccnc2OCC(F)F)n1 +Cc1cc(CC(=O)NC2CCCOc3c2ccc2ccccc32)no1 +O=C1CC(c2ccccc2Br)c2cc3c(cc2N1)OCO3 +CC(C(O)=NC1CCCC1)N1CCN(Cc2ccccc2)CC1 +Cc1ccc(C)c(Nc2nc(NCCCO)nc3c2cnn3C)c1 +CCN(CCc1ccc2c(c1)CCO2)Cc1nc2ccccc2c(=O)[nH]1 +CN(CCC#N)S(=O)(=O)c1ccc(Br)cc1 +CSc1ccc(NC(=O)Cn2c(=O)oc3ccccc32)cc1 +O=C(NC1CCCNC1=O)c1cc(F)cc(F)c1 +Cc1ccnc(NC(=O)c2ccn(COc3ccccc3)n2)n1 +Cc1nnc2n1CCN(C(C)c1nc(-c3cccs3)no1)C2 +Cc1cc(C2CCCN2C(=O)c2cc(-c3cccs3)on2)on1 +Cn1nc(-c2ccccc2)cc1C(=O)N1Cc2cncnc2C1 +CC(=O)Nc1ccccc1CNc1ccc2[nH]nc(C(N)=O)c2c1 +OC(CNc1cccc(F)c1)COc1cccc(F)c1 +Cc1cccc(NC(C(=O)Nc2cc(C)on2)c2ccccc2)c1 +Cc1ccnc(C2CCN(C(=O)c3cnn(C)c3)CC2)n1 +Cc1c(C(=O)N2CCC2(C)C)nnn1-c1cccc2cnccc12 +Nc1ccc(NC(=O)c2cc(F)cc(F)c2)c(Br)c1 +CC1CCC(OC(=O)c2cccc3[nH]ncc23)CC1 +Clc1cccc(CNc2cnn(-c3ncccn3)c2)c1 +CC(c1nc(-c2ccccc2)no1)N1CCn2c(nnc2C2CC2)C1 +Cc1ccc2c(c1)N(CC(=O)N1CCNCC1)C(=O)CO2 +Cc1nc(-c2cccnc2)sc1C(=O)NCCCOC(C)C +CC(C)NC(=O)NCCNc1ccc(C(F)(F)F)cn1 +CCc1nsc(N2CCN(C)c3ccccc3C2)n1 +CCC(C)NC(=O)COC(=O)c1cc(Cl)ccc1OC +NS(=O)(=O)c1ccc(NCc2cn[nH]c2)cc1 +COc1ccccc1CNC(=O)c1c(Br)cnn1C +C#CCOC(=O)C(CC)n1c(C)ccc(C(C)=O)c1=O +Cc1cc(NC(=O)CCc2nc(C)no2)n(Cc2ccccc2)n1 +CC(NC(=O)c1ccc(F)cc1F)c1ccc(NC(N)=O)cc1 +CC(C)c1ncc(CN2CCc3ccc(F)cc3C2)s1 +Cc1cccc(NC(=O)C23CCC(C)(C(O)C2)C3(C)C)n1 +NC(=O)CCCNC(=O)c1cn(Cc2ccccc2)nn1 +COc1ccc(NC(=O)c2ccc(N3CCCC3=O)cc2)cc1Cl +CCC(CO)N(Cc1cccs1)c1nc(C)nc2oc(C)nc12 +Cc1ccc(N(C)C(=O)c2cccc(OCC(=O)N(C)C)c2)c(C)c1 +CN(CC(C)(CO)CO)c1ccnc(C(C)(C)C)n1 +CC(C)(C)c1ccc(C(C#N)NC(=O)CCC2CCCO2)cc1 +CN(C)C(=O)c1nnsc1S(=O)(=O)c1ccc(Cl)cc1 +Cn1c(=O)c2c(nc3n(CC(N)=O)c(C(C)(C)C)cn23)n(C)c1=O +COC(=O)NCCc1nc(Cc2ccc(OC)cc2)no1 +CNC(=O)c1noc(Cn2ccc3ncccc3c2=O)n1 +Cc1ccc(NC(=O)c2nc3cccnc3n2C)cc1C +Cc1nsc(N2CCc3c(F)ccc(F)c3C2)n1 +CCOC(=O)c1c(C)oc(NC(=O)Nc2ccccc2)c1C(N)=O +CCOC(=O)c1c(NC(=O)C(C)C)sc(C(=O)N(C)C)c1C +COc1cc(F)c2c(c1)C(c1ccc(N)cc1)NCC2 +Cc1nnnn1-c1cccc(NCc2ccc(Cl)cc2Cl)c1 +CCN(CC(=O)NC(C)C)S(=O)(=O)N1CCC(C)C1 +Cc1ccc(-c2cc(=O)[nH]c(-c3ccco3)n2)cc1N +Cn1c(NC(=O)c2ccn(C(F)F)n2)nc2ccccc21 +Cn1cccc1C(=O)Nc1ccc(OC(F)F)cc1 +CCC(=O)N1CCN(C(=O)Cn2cccn2)CC1 +CCCCN(CC(N)=O)C(=O)C1CC(=O)N(CC)C1 +COc1cc(OC)cc(OCC(=O)N(C)C2CC2)c1 +O=C(Nc1ccc(F)nc1)C1COc2ccc(F)cc2C1 +CCOCc1ccccc1CNC(=O)N1CCOC(C)C1 +CCC(NC(=O)c1ccc(OC)nc1)c1cccs1 +COc1ccc2c(c1)CC(NS(=O)(=O)c1ccc(F)cc1)CO2 +CN(C)C(=O)c1cccc(CNc2cncc(-n3cccn3)n2)c1 +CCc1ocnc1C(=O)NC1CC(=O)N(CCc2ccccc2)C1 +Cc1ccoc1C(=O)N1CCC2C1CC(=O)N2c1cnn(C)c1 +COc1ccc(C(=O)Nc2sc(C)c(C)c2C(N)=O)cc1 +COCC(=O)N1CCC2(CC1)CC(=O)N(Cc1c(C)noc1C)C2 +Cc1cc(C(=O)NCC(=O)NCCc2cccc(F)c2)nn1C +Cc1noc(C)c1CNc1cc(F)ccc1Cl +CNC(=O)C(NC(=O)Cc1c(C)noc1C)c1ccccc1 +CC(C(=O)NC(c1ccc(F)cc1)C1CCCO1)n1cccn1 +OCCN(Cc1ncc(-c2cccc(F)c2)o1)c1ccccc1 +CCCc1cc(C(=O)NCC(C)(O)c2ccsc2)sc1C +CCCn1nnc2cc(C(=O)Nc3cccc(F)c3)ccc21 +C=C(C)CSc1nnc(C(C)NC(=O)OC(C)(C)C)o1 +Nc1ccccc1OCCNC(=O)C1CCCCC1 +Cc1csc(NC(=O)C2CN(C(=O)c3cnccn3)C2)n1 +CCc1cccc(CC)c1NC(=O)CCNC(=O)c1ccco1 +CC(C)c1cc(C(=O)NCc2ccc(N3CCCCC3=O)cc2)n[nH]1 +Cc1cc(S(=O)(=O)N2CCNCC2)c(C)s1 +Cc1oc(-c2ccco2)nc1CN1CCOc2ccc(F)cc21 +Oc1ccc2c(c1F)C(c1cccc3cc[nH]c13)NCC2 +COc1cccc(C2CCN2C(=O)CCc2n[nH]c3c2CCCC3)c1 +Cc1cccc(CN2CCOC3CN(CCc4ccccc4)CC32)n1 +CC(C)(C)NS(=O)(=O)c1ccc(Cl)c(N)c1 +N#Cc1c(CCCNC(=O)Nc2cccc(F)c2)n[nH]c1N +CCCN(C(=O)NC1CCCN(c2cccnc2)C1=O)C1CC1 +CCCC(=O)Nc1ccc(C(=O)Nc2cc(C)on2)cc1 +O=C(Cn1cnc2ccccc21)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1cc(N)cc(S(=O)(=O)NC(C)CO)c1C +CCC(C)NC(=O)c1ccc(N(CC)S(C)(=O)=O)cc1 +Cc1nnsc1-c1nnc2sc(-c3ccsc3)nn12 +COc1ccc(-c2n[nH]cc2CNc2cccc(-n3cnnn3)c2)cc1 +CC1CN(CC(O)Cn2cccn2)CCN1CC(O)c1ccccc1 +Cc1ccc(N2CC(C(=O)NCc3cccnc3)CC2=O)cc1 +CC(C)C(C)NC(=O)NCC1COc2ccccc2C1 +Cc1cc(C(=O)N2CCCC2c2nc(C)cc(O)n2)on1 +CN(Cc1cccs1)C(=O)CS(=O)c1cccs1 +O=C(CCNC(=O)c1ccsc1)Nc1ccc(-n2ccnc2)cc1 +Cc1ccc(C(C)NC(=O)c2ccc(N(C)C)cc2)s1 +CCC1CCN(C(=O)c2cnc(C3CCCO3)s2)C1 +O=S(=O)(c1ccc(F)c(F)c1)N1CCN(CCO)CC1 +C#CCn1c(=O)nc2n1C(=O)N(c1ccc(OC)cc1)C2 +Cc1cccc(N(C)S(=O)(=O)c2ccc(N)cc2)c1C +COc1ccc(Cl)cc1N1CCN(C(=O)C2CCC2)C(C)C1=O +CSc1ncnc(N2CCc3ccccc3C2)c1C#N +CCn1nnc(NC(=O)c2ccc(-c3cccc(Cl)c3)o2)n1 +CC1Oc2ccccc2OC1C(=O)NC(C(N)=O)c1ccccc1 +Cc1cc(C)c(S(=O)(=O)n2ccnc2C(C)C)cc1C +CCOC(=O)CC(NC(=O)c1ccccc1Cl)c1ccc(F)cc1 +CSc1ccc2c(C)cc(N3CCNC(=O)CC3)nc2c1 +CC(NC(=O)Nc1ccc(C#N)cc1)c1ccncc1 +CCc1nnc2n1CCN(C(=O)c1ccc3c(c1)NC(=O)CS3)C2 +Cc1noc(C)c1C(=O)Nc1cc(C(=O)N(C)C)cn(C)c1=O +Cc1nnc(SCc2nnc(C(F)(F)F)o2)n1N +COc1cc(C)ccc1OC(C)C(=O)n1ccnc1 +N#Cc1cn(-c2ccc(NC(=O)C3CCCO3)cc2)nc1N +CNS(=O)(=O)c1ccc(NC(=O)Cc2cccc(C)c2)cc1 +COc1ccc(F)cc1NC(=O)N(C)Cc1csc(C)n1 +N#Cc1c(-c2cccn2-c2ncccn2)cc(-c2cccs2)nc1N +CN(Cc1ccc(C#N)cc1)CC(C#N)CCC#N +CCCS(=O)(=O)c1ccc(NC(C)COC)cc1 +CN(C(=O)c1ccc(NC(=O)C2CC2)cc1)C1CC1 +CC(=O)c1c(C)nc(C2CC2)nc1SCC(=O)NCC(C)C +c1csc(-c2nn3c(CN4CCOCC4)nnc3s2)c1 +CC(CC#N)N(C)C(=O)Nc1cccc(Cl)c1Cl +CSc1ccc(CN(C)C(=O)Nc2cnccc2C)cc1 +COC(=O)c1sc(NC(=O)c2ccc(C)[nH]c2=O)nc1C1CC1 +CCc1cccc(OC(=O)CCc2nc(-c3cccnc3)no2)c1 +CCC(=O)NCc1ccccc1-c1cncc(OC)c1 +Cc1cc(O)c(C(C)C)cc1NC(=O)Cn1ccccc1=O +N#CC(c1ccccc1)C1CCCN1C(=O)c1c[nH]c2cccc(F)c12 +Cc1nn(C)c(C)c1S(=O)(=O)NC1(c2ccc(Cl)cc2)CC1 +CCC(CC)c1c(CO)nnn1Cc1ccccc1C +Cn1cc(NC(=O)Cc2ccc(Br)cc2)cn1 +Cc1cc(NC(=O)c2cn(C)nc2-c2cccs2)n(C)n1 +Cc1cc(-c2nc(-c3cccs3)no2)cc(S(N)(=O)=O)c1C +O=C1CCN(C(=O)CCCc2nc(-c3ccc(F)cc3)no2)CCN1 +N#Cc1cccc(OCc2ccc(S(=O)(=O)C(F)F)cc2)c1 +O=C(Cc1cccc(F)c1)NC1CCN(C(=O)C2CCCCC2)CC1 +C=CCN(CC(F)(F)F)C(=O)CN(C)c1ncnc2[nH]cnc12 +Cc1cc(C(=O)Nc2ccccn2)c2c(C)nn(C)c2n1 +CC(C)CC(C#N)CC(=O)N1CCN(c2ccccc2)CC1 +O=C(Cn1cnnn1)Nc1cc(-n2cncn2)ncn1 +CCc1ccc(C(=O)Nc2cccc(Oc3cnccn3)c2)o1 +COCC(=O)N1CCN(C(=O)NCC(C)C)CC1 +Cn1cc(S(=O)(=O)N2CCOCC2)cc1C(=O)N1CCOCC1 +Cc1ccc2c(c1)OCCN2Cc1ccc(C(=O)N(C)C)[nH]1 +N#CCOc1ccc(NC(=O)c2cccc(F)c2)cc1 +COC(=O)C1CC(O)CCN1C(=O)Cc1ccc(OC)c(C)c1 +CN1C(=O)COc2ccc(-c3cc(N)nn3C)cc21 +CCn1cnnc1-c1cccc(NC(=O)CN(C)S(C)(=O)=O)c1 +Cc1nc(-c2ccc(NC(=O)c3ccco3)cc2)cs1 +Cc1noc(C2CCCN(C(=O)NC3CCCC3)C2)n1 +O=C(NCCS(=O)(=O)NCc1ccc(F)cc1)c1ccccc1 +O=C(OCC(=O)N1CCCCC1)c1ccc(O)cc1 +COc1cccc(-n2nnnc2S(=O)(=O)Cc2ccccc2)c1 +O=C(NCCO)Nc1ccc(Cl)c(C(F)(F)F)c1 +CCc1ccc(S(=O)(=O)N(C)CC(O)COC)cc1 +N#Cc1cc(F)c(NCCCNC(=O)c2cccc(O)c2)c(F)c1 +CN(Cc1ccc(C#N)cc1)C(=O)CCNc1ccccc1 +NC(=O)C1CN(C(=O)c2cccc(-n3cccc3)c2)CCO1 +C#CCOc1ccc(C(=O)N2CCC(C)CC2)cc1 +CC(C)CC(NS(=O)(=O)N(C)C)C(=O)N(C)C +CCCNC(=O)c1ccc(NC(=O)N(C)Cc2ccoc2C)cc1 +Nc1cc(F)ccc1NC(=O)c1ccc(Cl)cc1 +Cc1nn2cc(C(=O)NCC(=O)NC(C)C)nc2s1 +O=S(=O)(Cc1nc2ccccc2s1)c1ccc(Cl)cc1 +O=C(COc1ccccc1Cl)Nc1ccccc1C(=O)NC1CC1 +CCOc1ccc(C(C)NC(=O)NCc2ccco2)cc1 +NC(C(=O)NC1CC1)c1ccc(Br)cc1 +CCN(Cc1ccccc1)C(=O)c1cnc(N(C)C)nc1N +Nc1ccccc1OCCCn1nnc2cc3c(cc21)OCO3 +CCCC(C)(C)NS(=O)(=O)N1CCCCCC1 +CCC(=O)NCC(=O)NC1(c2cccc(Br)c2)CCC1 +CC(CNC(=O)c1cccc(F)c1)N1CCOCC1 +Cc1cccc(NC(=O)NCc2noc3ccccc23)n1 +CCOC(=O)CCC(=O)c1ccc(Cl)cc1OC +O=C(c1c(F)cccc1F)N1CCN(CC2=CCCOC2)CC1 +CC(C)n1c(C2CCCN(C(=O)Cn3ncnn3)C2)nn(C)c1=O +CC(C)N(Cc1ccccc1)C(=O)Cc1cccs1 +O=C(c1ccc(C2OCCO2)cc1)c1cccc(F)c1 +CCN(C)S(=O)(=O)N(CC(C)O)C1CCCCC1 +COC(=O)N(C)CCCC(=O)NCC1(O)CCCc2ccccc21 +CCOc1ccc(CCn2nc(C)c(N)c2C)cc1 +O=C(c1cnccn1)N1CC(C(=O)N2CCc3ccccc32)C1 +CCCC(=O)N1CC2CC(C1)c1cccc(=O)n1C2 +O=C(NCCc1cccs1)c1cccc(-n2cnnn2)c1 +CCOC(=O)c1c(NC(C)=O)sc2c1CCN(C(=O)OCC)C2 +O=C(CCn1ccccc1=O)Oc1ccccc1Cl +COCCCN(C)S(=O)(=O)c1ccc(C#N)cc1C +O=C(c1ccccc1)c1ccc(OCCO)cc1O +CC(C(=O)Nc1cccc(F)c1)N1CCN(C2CCOC2=O)CC1 +CCc1ccccc1CNC(=O)Nc1ccccc1S(C)(=O)=O +Cc1noc2nc(C(C)C)cc(C(=O)N3CCCC3)c12 +Cc1ccc(Cl)cc1NS(=O)(=O)c1ccc(N)cc1 +C(=CCN1CCOC2CCCCC21)CN1CCOC2CCCCC21 +CCOCCOC(C)C(=O)N1CCCC1c1ccccc1Cl +O=S(=O)(c1cccc(F)c1F)N1CCOc2ccc(F)cc21 +CCC(=O)N1CCN(Cc2nc3cc(NC(C)=O)ccc3n2C)CC1 +CN(c1ccc2ccc(F)cc2n1)C1CCN(S(C)(=O)=O)CC1 +Cc1nn2c(CNC(=O)c3ccc(C(C)C)cc3)c(C)nc2s1 +O=C(NC1CC1)c1ccc(Oc2cnc3ccccc3n2)cc1 +O=C(NCCC(O)c1ccoc1)C12CC3CC(CC(C3)C1)C2 +CC1CN(C(C)(C)CNc2ncnc3ccc(F)cc23)CC(C)O1 +CCCC(C)N1CC(C(=O)NCc2cccc(OC)c2)CC1=O +CCN(CC)C(=O)C(Cc1ccccc1)c1cccc(N)c1 +O=C(C1CC1c1c(F)cccc1Cl)N1CCOCC1C1CC1 +CCC1CCCN(C(=O)Cn2c(=O)[nH]c3ccccc3c2=O)C1 +COC(=O)c1ccc(C(=O)N2CCC(c3cccs3)CC2)cc1 +CCC(CO)NC(=O)Nc1nnc(C(F)(F)F)s1 +O=C(NCCN1CCNC1=O)c1coc(CN2CCOCC2)c1 +CCCCNC(=O)c1ccc2c(OC)n(C)nc2c1 +COc1ccc(C2NCCc3ccc(F)c(OC)c32)cc1 +Cc1csc(N(C(=O)c2ccccn2)c2ccccc2)n1 +COCc1cc(C(=O)NC(C(N)=O)C(C)(C)C)ccc1F +Cc1cc(F)cc2c1CCNC2c1cnccc1Cl +Cc1ccccc1CC(=O)OCc1ccc(C(N)=O)cc1 +O=C1C2CCC(C2)N1Cc1ccccc1C(F)(F)F +Cc1ccc(S(=O)(=O)NC(=O)c2cnc(N(C)C)s2)cc1 +Cc1noc(C2CCCN2C(=O)c2cnn(-c3ccccc3)c2C)n1 +Cc1cc(C)cc(NC(=O)c2cc3cnn(C)c3nc2N)c1 +NC(=O)c1ccc(Cn2cnc3c(cnn3-c3ccccc3)c2=O)cc1 +Cc1cc(C(=O)Cn2cnc(C#N)c2C#N)c(C)n1-c1nccs1 +O=C(NCCNC(=O)c1cc2cnsc2s1)c1cccs1 +O=C(c1nc(NCCc2ccccc2)ncc1Cl)N1CCOCC1 +CCNC(=O)c1ccc(NC(=O)c2cccc(C)c2)c(C)c1 +Cc1ccc(C(C(=O)NCCCn2cc(Cl)cn2)N(C)C)cc1 +Cc1cnc2n(c1=O)CC(C(=O)NCCOCCO)CS2 +CCN(CC(F)(F)F)C(=O)CCc1cccc(N)c1 +CCN(Cc1ccc(C#N)cc1F)C(=O)c1csc(NC(C)=O)n1 +O=C(Cc1ccc[nH]1)Nc1ccc(C(=O)NC2CC2)cc1 +C=C(C)CN(CC)C(=O)NCc1ccccc1-n1ccnc1 +O=C(C1CC2CCC1C2)N1CCN(c2ncccn2)CC1 +COc1ccccc1NC(=O)C(C)NC(=O)c1ccccc1F +Cc1ccc(OCCC(=O)N2CCOCC2c2ncon2)c(C)c1 +Cc1cn(C2CC2)c(=O)c(C#N)c1-c1cccnc1 +CCOC(=O)c1cccc2nc(C(C)O)n(C3CC3)c12 +CCCNC(=O)CN(c1cccc(F)c1)S(C)(=O)=O +Cc1nn(CC(C)C)c(C)c1CC(=O)NC(C1CC1)C1CC1 +C#CCN1CCN(S(=O)(=O)CC2CCCCC2)CC1 +CCOC(C)C(=O)N(C)Cc1c(C)nc2sc(C)cn12 +Cc1cc(C)c(C(O)CCc2nc(C)cs2)c(C)c1 +Cc1cc(NC(=O)C2CCCN2C(=O)COc2ccccc2)no1 +CCN(Cc1c(F)cccc1Cl)C(=O)c1cccc(COC)n1 +CC(NC(=O)NC(C)C1CC1)c1cccc(F)c1 +COCCn1cnnc1C1CN(S(=O)(=O)c2cn(C)cn2)C1 +Cc1cc(C(C#N)C(=O)c2cc(C)n(Cc3ccco3)c2C)nc(C)n1 +Cc1ccc(NC(C)c2cc(F)ccc2F)cc1C(N)=O +O=C(NCCCO)C1(c2ccc(Br)cc2)CCC1 +O=C(c1ccc[nH]c1=O)N1CCN(c2nccs2)CC1 +Cc1cnn(CC2CCCN2C(=O)CCc2c[nH]c3ccccc23)c1 +Nc1nccnc1C(=O)NCc1ccc(COCC(F)(F)F)cc1 +NC(=O)c1ccc(CNCCc2ccc(F)cc2)c(F)c1 +Cn1c(CSc2nnnn2Cc2ccco2)cc(=O)n(C)c1=O +Cc1cc(OC(C)(C)C(=O)N2CCN(C)CC2)cc(C)c1Cl +CSc1ccc(CN(C)C(=O)Cc2ccc(C)nc2)cc1 +CN(CC(F)(F)F)C(=O)CNC(=O)N1CCC2CCCCC21 +C=CCn1c(C)nnc1SCC(=O)Nc1ccc(Cl)cn1 +O=C(Cc1ccc(F)c(F)c1)OCCn1ccccc1=O +CCn1nnc2cc(C(=O)N(C)c3ccc(OC)c(OC)c3)ccc21 +CC(=O)Nc1ccc(NC(=O)C(C)OC(=O)c2ccc(O)cc2)cc1 +Cc1ccc(NC(=O)CCc2nc3ccccc3[nH]c2=O)c(C)c1 +Cn1cnc(CNC(=O)N2CCC(Oc3cccc(C#N)c3)CC2)n1 +COC(=O)C(C#N)c1nc2ccccc2nc1NCc1cccs1 +CCOc1ccc(NC(=O)Cn2c(C)nc3ccccc3c2=O)cc1 +Nc1ccc2oc(C(=O)NCCC(F)(F)F)cc2c1 +Cc1ccc(S(=O)(=O)N(CCO)CCO)cc1Cl +Cc1cnn(-c2ccccc2)c1NC(=O)c1ccncc1F +COc1ccc(Cc2noc(-c3cccc4cn[nH]c34)n2)cc1OC +Cn1c(CN(CCCO)C2CCc3ccccc32)nnc1C1CC1 +CCCCCN(C(=O)c1ccc(NC)nc1)C(C)C +Nc1cccc(-c2nnc(NC(=O)c3cnccn3)s2)c1 +CN(Cc1nnc2n1CCC2)C(=O)c1ccc(S(C)(=O)=O)cc1 +O=C1C(C(O)c2ccccc2)OCCN1c1ccccc1 +Cc1ccc(C(C)(C)C)cc1S(=O)(=O)NCc1ncoc1C +CN(C(=O)CCOc1ccc(Cl)c(Cl)c1)C1(C#N)CCC1 +CN1C(=O)C2CCC1CN(S(=O)(=O)c1ccc(F)c(Cl)c1)C2 +Cc1cc(-c2ccc(C(=O)N(C)C)cc2)ccc1O +COCC(O)CN(C)C(=O)c1cc(C)c(C)s1 +FC(F)(F)c1ccc(-n2cc(NCc3cscn3)cn2)cc1 +CCCC1CN(C(=O)c2cc3ccc(F)cc3nc2C)CCO1 +Cc1ccc(OCCNC(=O)CNC(=O)c2cc(F)cc(F)c2)cc1 +Cc1nc(COc2ccc(NC(=O)c3ccc[nH]c3=O)cc2)no1 +Cc1ccc(-c2nnc3ccc(SCC(N)=O)nn23)cc1 +O=c1[nH]nc(CNCc2c[nH]nc2-c2ccc(F)cc2)c2ccccc12 +COc1cc(C(=O)N2CCN(C(C)=O)CC2)cc(Cl)c1OC +CCOC(=O)c1cnn(-c2ccccc2OC)c1C +Cn1cc(C(=O)NCc2ccc(F)cc2)c(C(C)(C)C)n1 +COCCSc1nc(=O)n(CC2CCCO2)c2c1CCCC2 +Cc1ccc(=O)n(C(C)C(=O)Nc2ccc(F)c(Cl)c2)n1 +N#CCc1ccc(OCCCn2ccc(N)n2)cc1 +COc1cccc(-c2nc(C)nc(N3CCCC3)c2N)c1 +O=C(CSc1ncn[nH]1)N1CCCC2CCCCC21 +CC(=O)N1CCC(Cc2ccc(-c3ccncc3)cc2)(C(N)=O)C1 +CCN(CC(F)(F)F)C(=O)CCCc1nc2ccccc2s1 +CCNC(=O)COc1ccc(NC(=O)c2ccc(F)cc2)cc1 +CC(C)Oc1ccc(OC2CC2)c(C(=O)N(C)C)n1 +CCNC(=O)c1ccc(-c2cc(NCCO)nc3[nH]ccc23)cc1 +O=c1[nH]c2cc(Cl)c(C(O)c3ccc(Cl)cc3)cc2[nH]1 +COc1ccc(C(=O)Nc2cccc(SC)c2)nn1 +CC(=O)Nc1ccc(S(=O)(=O)N=c2[nH]c3c(s2)CCC3)cc1 +CCCNc1nc(-c2sc(C3CC3)nc2C2CC2)cs1 +CCCCc1c(C#N)nnn1-c1ccc(OCC)cc1 +CCc1cnc(NC(=O)CNS(=O)(=O)c2cn(C)cn2)s1 +O=C(Nc1cc2c(cc1C(O)c1ccccc1)OCCO2)C1CC1 +COc1cccc(NC(=O)c2cc(Cl)cc3cccnc23)c1 +Cc1ccc(C(=O)Nc2nn(-c3ccccc3Cl)cc2C)c(=O)[nH]1 +N#Cc1ccc(-c2noc(COCC3CCCO3)n2)nc1 +Cc1sc2ncnc(SCC(C)C#N)c2c1C +COc1ccccc1N(C)C(=O)CN1C(=O)CCCc2sccc21 +Cc1cc(CN2CCN(C(=O)NC(C)Cn3cccn3)CC2)no1 +CN(Cc1cnn(C)c1)C(=O)c1cccc(NC(=O)OC(C)(C)C)c1 +CCc1nc(-c2ccco2)ncc1Br +COc1cccc2c1N(C(=O)c1csc(C)n1)CCC2 +Cc1ccc(CNC(=O)COCC(F)(F)F)s1 +CC(C(=O)N1c2ccccc2CC1C)N1CCN(C(=O)N(C)C)CC1 +Cc1ccc(NCCC(O)c2ccc(F)c(N)c2)cc1 +CN(CCC(=O)OC(C)(C)C)Cc1cnc2ccc(C#N)cn12 +CCN(Cc1ccco1)C(=O)Nc1ccccc1Cl +CC(C)c1nc(CN2CCOCC2)sc1CO +COc1ccccc1N1CCN(CC(=O)N2CCCC(C)C2)C1=O +O=C(NCCc1ccc(F)cc1)c1cnn(-c2ccc(F)cc2)n1 +Fc1ccc(C2=Nc3ncnn3C(c3ccco3)C2)cc1 +CCOC(=O)C1CCCN(C(=O)c2ccc(C)cc2O)C1 +Cc1cc(C)n(CC(=O)Nc2cccc3ncccc23)c(=O)n1 +CSc1nnc(N)n1C(C)C(=O)NCc1ccccc1 +CSc1ccc(CNC(=O)c2cnc3c(C)cccn3c2=O)cc1 +CS(=O)(=O)NCCc1ccc(C(=O)NCC2CC2)cc1 +COc1ccccc1C(C)N(C)S(=O)(=O)N(C)C +COCc1ccc(C(=O)Nc2ccc(-n3ccnc3)cc2)cc1 +C=CCNC(=O)c1cc(-c2ccc(OC)cc2F)n(CC)n1 +Cc1csc(CNC(C)c2ccc(-c3cccnc3)cc2)n1 +CC(C)Cn1nccc1NC(=O)CCc1ccccc1 +COc1cccc(C(=O)CCN2CCc3ccccc3C2)c1 +N#Cc1cccc(CSc2nc(N)c(C#N)cc2C#N)c1 +Cn1cc2ncn(CC3CCCN(c4ncccn4)C3)c(=O)c2n1 +O=C(CSc1nccc(=O)[nH]1)Nc1ccc(Cl)c(Cl)c1 +CCC(C)NC(=O)CCC(O)c1ccc(C(C)C)cc1 +CC(C)C1COC(=O)N1Cc1cccc(-n2cccn2)c1 +CCc1ncnc2c1CCN(C(=O)c1ccc[nH]1)CC2 +CCn1nc(C)c(Cl)c1C(=O)NCCc1ccc(C)o1 +Cc1cc(-c2c[nH]nc2C2CCCN2C(=O)OC(C)(C)C)on1 +CC1CCCCN1C(=O)c1cccc(Oc2ncccn2)c1 +Cn1cc(N2CCN(Cc3ccco3)CC2=O)cn1 +CCOc1ccccc1OC(c1ccccc1)C(O)CO +CC(=O)Nc1ccc(CC(=O)Nc2ccc(C)c(Cl)c2)cc1 +Cc1ccc(N)c2c1N(C)S(=O)(=O)C21CCCC1 +Cc1cc(C)cc(NC(=O)c2ccc3[nH]c(C)nc3c2)c1 +CCNC(=O)CNc1cccc(C(=O)NC(C)(C)C)c1 +CCN1CC(C(=O)N(C)Cc2nc(-c3ccncc3)no2)CC1=O +NC(=O)CCn1ccc(Nc2ncc(Br)cn2)n1 +COc1ccc(C(CC(=O)N2CCOCC2)c2ccccc2)cc1 +CCOC(=O)NCCOc1cccc2c1OC(C)(C)C2 +COc1ccc(C(=O)N(C)Cc2cccs2)cc1F +CC(=O)N1CCc2cc(C(=O)NCCCOCC(C)C)ccc21 +Cc1cn(-c2ccccc2)nc1NC(=O)N1CCc2ccccc2C1 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(F)cc1F +CCOc1ccc(C(=O)NC2(c3ccccc3)CCC2)cn1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2nc3ccc(F)cc3s2)c1C +CCOc1cc(N)cnc1NCc1ccccc1Cl +COc1cc2nc(CC(C)C)n(CCCO)c2cc1OC +CC1CCC(Nc2ccc(S(N)(=O)=O)cc2)CC1 +CC(=O)c1cccc(NC(=O)N2CCC(Nc3cccnc3)CC2)c1 +Cc1nnc(CN2CC(Cc3ccccc3)CC2=O)o1 +CCCC(C)(C)NC(=O)c1cccc(N2CCCS2(=O)=O)c1 +CC(CC(=O)Nc1ccc2c(c1)OCCO2)C(N)=O +Cc1cc(C)c(NC(=O)Cc2csc(-c3cccnc3)n2)c(C)n1 +Cc1csc2nc(Cc3ccccc3)[nH]c(=O)c12 +COc1ccc(NC(=O)Cn2cc(CCO)cn2)cc1 +O=C(c1ccncc1F)N1CCC(c2nc3ccccc3[nH]2)CC1 +COc1cc(C(=O)Nc2cccc(C(N)=O)c2)cc(OC)c1C +O=C(NCCC1=CCCCC1)N1CCC(N2CCNC2=O)CC1 +CCOc1c(F)cccc1C(=O)Nc1ccccc1-c1nnc(C)o1 +O=C(NCCc1cc(F)cc(F)c1)Nc1cnn(CC(F)F)c1 +CCC(O)c1cc(F)c2c(c1)C(NC(=O)C1CC1)CCO2 +CC(C)(C)CN(CCCO)C(=O)c1ccc(C#N)cn1 +CCCCNC(=O)c1csc(C(=O)NC2CC2)n1 +Cn1cc(NC(=O)c2cc3c(s2)CCC3)ccc1=O +O=C(Cc1cn2ccsc2n1)Nc1c(F)cccc1N1CCCC1 +OC(Cn1cncn1)(c1ccc(F)cc1)c1ccccn1 +CC(C)c1ccccc1OCC(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(Cn1ncc(=O)c2ccccc21)Nc1cccc(C(F)(F)F)c1 +CC1(CNC(=O)N2CCC(N3CCCC3=O)CC2)CCCC1 +Cn1nnc2c(SCC(=O)NC3CC3)ncnc21 +CCc1c(C(=O)N2CCC(OC)CC2)cnn1Cc1ccccc1 +CC(C)(C)OC(=O)N1CCN(CC(=O)NCCC#N)CC1 +O=C(COC1CCCC1)N1CC2COCC2(COc2cccnc2)C1 +CCOC(=O)c1cccc(NC(=O)NCC2CC2C)c1 +CCNC(=O)NC1(C(=O)NCc2ccncc2)CCCC1 +COCc1cc(NCc2ccc3c(c2)CCCO3)ncn1 +COC(=O)C(CC(C)C)NC(=O)c1cc(C(C)C)nc2onc(C)c12 +O=C(Nc1ccc(C(=O)NCc2ccncc2)s1)c1ccco1 +CC(=O)OCCNc1ncc(C(F)(F)F)cc1Cl +CCOc1cccc(CNC(=O)c2cc(F)ccc2C)c1 +NC(=O)COc1cccc(C(=O)NC2CCSc3ccccc32)c1 +Cc1c(NCC(=O)Nc2ccccc2F)cccc1C(N)=O +O=C(Cn1nc2nc(N3CCCC3)ccn2c1=O)Nc1nccs1 +CCOCCC1CCN(C(=O)Cc2cccc(F)c2F)CC1 +Cc1ccc(OCC(=O)Nc2ccccc2SCC(C)C#N)nc1 +CC(=O)N1CCN(C(=O)CCOc2ccc(C)cc2)CC1 +Cc1ncc(C(C)NC2CCN(c3ccc(F)cc3F)C2)s1 +CCCC(=O)N1CCCC(C(=O)OC2CCCC2OC)C1 +COc1nc2c(cc1C(=O)N1CC3CC=CCC3C1)CCC2 +CCOc1cc(C(=O)N(C)C)ccc1NC(=O)C1CC1c1ccco1 +COc1ccc(C(NC(=O)N(C)Cc2cnn(C)c2)C(C)C)cc1 +Cn1ccc(CC(=O)OCCNc2ncccc2C#N)n1 +CCc1nnc(NC(=O)N(C)C(C)c2cccnc2)s1 +Cc1cc(C(=O)Cn2cnc(C#N)n2)c(C)n1C1CC1 +O=C(NCC(O)c1ccc(Cl)cc1)C1(O)Cc2ccccc2C1 +COc1ccc(Cl)c2c1CCNC2C1CCC1 +COCCNC(=O)c1nn(-c2ccccc2)c2c(=O)n(C)cnc12 +COc1ccc(-c2nnn(CC(=O)NC(C)C)n2)cc1OC +Cc1cc(-n2cnc3ccccc32)cn2nc(N)nc12 +COc1ccc(CNC(=O)Nc2ccccc2)cc1OC +CCCN1CC(C(=O)N2CCC3(CC2)NCCNC3=O)CCC1=O +NC(=O)N1CCC2(CC1)CCN(c1ncccn1)CC2 +COc1ccccc1C1CNC(=O)c2nc(-c3ccc(C)o3)[nH]c2C1 +Cc1n[nH]cc1NC(=O)c1ccc(OC(C)C)cc1 +CCc1ccccc1CNC(=O)NCCNC(=O)c1ccccc1O +O=C(Nc1cccc2[nH]cnc12)c1cccc(Oc2cnccn2)c1 +CCOc1ccc(NC(=O)NCCN2CCOCC2)c(C)c1 +Cc1ccc(NC(=O)NCc2cccc(O)c2)cc1C +CN(C)C(=O)C1CCCN1C(=O)c1cc(F)cc(F)c1 +C=CCn1c(COC)nnc1SCc1ccccc1 +COC(=O)c1ccc2c(c1)nc(C1CC1)n2C1CCCC1 +CC(C)(CNC(=O)CCC(=O)N1CCOCC1)c1ccccc1 +O=C(OCCN1CCOC1=O)c1csc(Cc2ccccc2)n1 +Cc1cc(NCc2nccs2)ccc1C(=O)OC(C)(C)C +CNC(=O)COC1CN(C(=O)c2ncc(C(C)(C)C)o2)C1 +Cc1nc(CN2C(=O)COc3ccc(F)cc32)n(C)n1 +Cc1ccc(NC(=O)C2OCCc3ccccc32)nc1 +O=C(Nc1cnn(CC(F)F)c1)c1cccc(Cl)c1 +CC(C)Nc1nc(NC(C)C)nc(SCC(N)=O)n1 +COc1ccc(S(=O)(=O)N(C)CCc2nccs2)c(C)c1F +Cc1ccc(S(=O)(=O)NCC(=O)NCc2ccncc2)cc1 +CN(CC(C)(CO)CO)C(=O)c1cc(C2CCCCC2)n[nH]1 +O=C(Nc1cccc2ccccc12)c1ccc(-n2cnnn2)cc1 +CC(=O)N(C)Cc1cccc(NC(=O)CCc2ccc(F)cc2)c1 +CN(C(=O)c1ccc(CC#N)cc1)c1ccccc1 +Cc1cc(C(=O)NCC(C)CCO)nn1-c1ccccc1Cl +Cc1ccc(OC(=O)CCCc2nc(C3CC3)no2)c(Cl)c1 +CC1CCCN(C(=O)c2ccc(-c3ccco3)o2)C1 +CC(=O)Nc1cccc2c1ccn2CC(=O)NCC1CCCO1 +O=C(Nc1cc(F)c(F)c(F)c1)c1scnc1C1CC1 +Cc1nncn1CCNC(=O)C1(Cc2ccccc2)CC2CCC1C2 +CC(=O)Nc1ccc(NC(=O)CSc2nnc(C3CC3)n2C)cc1 +Cc1ncccc1OCC(=O)N1CCc2sccc2C1 +CC(OC(=O)c1ccc2c(c1)NC(=O)CS2)c1ccccc1 +Cc1cc(C(=O)NCC2CCN(c3ccccc3)C2)c(C)n1C1CC1 +CCC(C)(C)NS(=O)(=O)c1cc(S(C)(=O)=O)ccc1C +CC(C)n1nccc1NC(=O)CCc1nc(-c2ccsc2)no1 +CC(=O)NCCNC(=O)Nc1cc(C)cc(C)n1 +COc1cc(C)c(-c2cc(C)nc(N)n2)cc1Cl +CCc1nnc(NCC(=O)c2ccc(C)c(F)c2)s1 +COC(=O)c1ccc(F)c(NC(=O)N(C)Cc2ccoc2C)c1 +CN(C)c1cccc(CNC(=O)Nc2ccc(F)c(F)c2F)c1 +CCNc1ccc(Br)cc1NC(=O)c1ncoc1C +CC(O)CN1CCN(Cc2nnc(C3CC3)o2)CC1C +O=C1CN(C(=O)C#Cc2ccccc2)C2CCCCC2N1 +CCOC(=O)c1cccc2nc(C(C)O)n(CC#N)c12 +COc1ccc(CC(=O)Cc2ccc(Cl)cc2)cc1OC +CCCC(C(=O)OCC(=O)N1CCCC1)c1ccccc1 +CCOC(=O)C1(NC(=O)c2ccoc2C)Cc2ccccc2C1 +O=C(NC1CCN(c2nccs2)CC1)c1cc2ccccc2[nH]1 +Clc1ccccc1Cc1nnc2sc(Cn3cccn3)nn12 +COC(=O)c1ccc(CS(=O)(=O)NC2CCCC2)cc1 +O=C(Cc1ccc(Cl)cc1)NCc1nnc2ccccn12 +CCNC(=O)CCc1ccc(S(=O)(=O)NC2CCCCC2)cc1 +CC(=O)N1CCN(C(=O)COc2cc(C)ccc2C(C)C)CC1 +CN(Cc1nccs1)C(=O)c1c(F)cc(Br)cc1F +COCCN(C(=O)Nc1ccccc1)C(C)c1cccnc1 +COc1ccc(Oc2ncnc(NC3CCCC3)c2N)cc1 +CC1(C)CCC(CNC(=O)c2cc(C(N)=O)cs2)CC1 +O=C(OCC(F)(F)F)c1scnc1C1CC1 +O=C(Nc1nnc(Cc2cccs2)o1)c1ccccc1Cl +O=C(Nc1ccc2c(c1)COC2=O)c1ccncc1 +Cn1cc(NC(=O)C2CCCN2S(C)(=O)=O)cn1 +COc1cc2c(cc1NC(C)=O)-c1ccc(NC(C)=O)cc1C2 +CC1CN(CCCCOc2ccc(F)cc2)CC(C)O1 +CNC(=O)c1cc(OC)c(OC)cc1NC(=O)c1ccccc1 +Nc1cc(F)c(N(CC(F)(F)F)C2CC2)c(F)c1 +CCc1cnc(CN(C)C(=O)Nc2cc(F)ccc2OC)s1 +CCNc1nnc(CCn2nc(C)c(Br)c2C)s1 +CSc1cccc(NCc2cn(C)nc2C(C)C)c1 +O=C(NCc1nncn1C1CC1)Nc1cccc(Cl)c1F +Cc1cccc(CC(=O)NCC2CN3CCCCC3CO2)c1 +CC(C(=O)NCc1ccnc(OC(C)(C)C)c1)C1CCOCC1 +Nc1ccc(-c2nn3cnnc3s2)c(Cl)c1 +CCOC(=O)CCC1NCCc2c(F)cccc21 +CCN(CC(F)(F)F)C(=O)c1c(C)nn2cccnc12 +CC(CO)NC(=O)NCCC(=O)Nc1ccc(Br)cc1 +COCCNC(=O)c1cc2sc(C)cc2n1Cc1ccccc1 +CN(Cc1nccs1)C1CCCN(c2ccc(C#N)cc2)C1=O +CCc1noc(CC)c1CC(=O)NC1CCCN(c2cnn(C)c2)C1 +Cc1ccccc1CNC(=O)CNC(=O)Cc1ccccc1 +O=C(Cc1ccccc1F)N1CCN(Cc2ccccc2F)CC1 +CC1CCCC2CCCN(C(=O)c3ccc(N4CCCC4=O)cc3)C12 +CC(C)(C)C(=O)CSc1n[nH]c(=O)n1CCc1ccccc1 +CCc1nnc(CNC(=O)c2c(C)c(C)nc3ccc(C)cc23)o1 +Cc1nc2n(c(=O)c1Cc1ccc(Br)cc1)CCS2 +Nc1ccc(OCCCOCC(F)(F)F)c(F)c1 +O=C(Nc1nc2ccccc2s1)c1cc(F)ccc1-n1cnnn1 +O=C(NCc1ccccc1F)N1CCN(Cc2ccco2)CC1 +NC(=O)CSc1ncnc2c1sc1nc3ccccc3cc12 +Cn1ncc2c(N3CCC(CNc4ncccc4C#N)C3)ncnc21 +CC(C)Oc1ccc(NC(=O)N(C)Cc2cnn(C)c2)c(F)c1 +O=C(c1csc(NC2CC2)n1)N1CCC2(O)CCCCC2C1 +CCCCN(CC)C(=O)COc1ccccc1N +COC(=O)CC(NC(=O)c1cscn1)c1ccc(OC)cc1 +COc1cc(C)c(NC(=O)c2c(F)cccc2F)cc1OC +CC(C(=O)Nc1ccc(O)cc1F)n1cnc2ccccc21 +CCOc1cc(C2C(C(N)=O)C(C)=Nc3nnnn32)ccc1OC +O=C1CCc2c(OCc3noc(C4CC4)n3)cccc21 +Cc1ccc(S(=O)(=O)C(C)C(=O)Nc2c(C)cccc2C)c(C)c1 +Cc1csc(CNC(=O)Cc2ccc3c(c2)CCCC3)n1 +CCCC(=O)Nc1cccc(NCc2cccc(C(=O)NC)c2)c1C +c1ccc(COC2CC3CN(Cc4nccs4)CCN3C2)nc1 +C=CCNC(=O)c1cn(Cc2ccco2)c2cccc(N)c2c1=O +CC(COc1ccccc1F)NS(=O)(=O)N1CCCC1 +Cn1cc(C(=O)OCc2csc(COc3ccc(F)cc3)n2)cn1 +COC(=O)C(NC(=O)c1cccc(OC)c1F)C(C)(C)C +C#CCOc1ccc(N(C)C(=O)c2ccccc2-n2ccnn2)cc1 +CC(C)NC(=O)COc1cccc(CC(N)=O)c1 +CCn1nc(C(=O)Nc2ccc3c(c2)OCCO3)cc1C +CCN(Cc1ccncc1)C(=O)c1ccc(C)c(OC)c1 +O=C(NCCCc1ccccc1)c1ccc2ncccc2n1 +O=C(NCCCc1nc2ccccc2[nH]1)NCc1ccccc1Cl +CCOC(=O)C1=C(CC)N(C)C(=O)NC1c1ccc(OC)c(O)c1 +COCCOc1ccc(NC(=O)NC2c3ccccc3CC2O)cn1 +Cc1nn(CC(=O)c2cccs2)c(C)c1Br +COc1cccc(C(=O)Nc2cccc(N)c2C)c1OC +Cc1cc(NC(=O)NCc2ccccc2)c(C(F)(F)F)o1 +COC(C)C(=O)N(Cc1ccc(C(F)(F)F)cc1)C1CC1 +COCc1nn2c(C)c(C(=O)OC)nnc2c1-c1ccc(OC)cc1 +CC(=O)Nc1ccc(CC(=O)Nc2cccc(C)n2)cc1 +COCCN1CC(C(=O)N2CCCC(c3nccs3)C2)CC1=O +CCC1CCCCN1C(=O)CC(NC(C)=O)c1ccccc1 +Cc1cc(NC(=O)CN2c3ccccc3CCC2C)on1 +CC(=O)c1ccccc1NC(=O)c1cc(Cl)c2c(c1)OCO2 +Cc1c(C(=O)N(C)c2ccccc2)cn2nc[nH]c(=O)c12 +CCCC1CN(C(=O)c2cn(C)nc2-c2ccccc2OC)CCO1 +COc1ccc(NC(=O)Cn2ccc3c(=O)n(C)ccc32)cc1OC +CCS(=O)c1ccccc1C(=O)NCc1ccc(F)cc1 +CCCNC(=O)C1(NC(=O)Cc2csc(CC)n2)CCCCC1 +CS(=O)(=O)NCC(=O)NCCc1cccnc1 +COc1ccc(NC(=O)NCC(O)Cc2ccccc2)cc1 +COC(=O)C(C)Sc1nnc(-c2ccc(OC)cc2OC)o1 +CNC(=O)c1nnn(-c2cccc(Cl)c2)c1N +COC(=O)CN(C(=O)C(C)Sc1ccc(Cl)cc1)C(C)C +COCC1CCN(C(=O)c2cccc(Br)c2C)C1 +Cc1cnc(C2NCCc3c(O)ccc(Cl)c32)cn1 +N#Cc1cnn2ccn(Cc3ccc(F)c(F)c3)c12 +Cc1ccnc(NC(=O)CCOc2cccc(Cl)c2)c1 +CN(Cc1nnc2ccccn12)c1ccc(C#N)c(Cl)c1 +CC(=O)c1ccc(NC(=O)CSc2nc(C)n[nH]2)cc1 +O=C(CNc1ccc(Cl)c(F)c1)NCC1CC1 +CNc1ncc(C(=O)N2CC(Oc3c(C)cccc3C)C2)cn1 +CCOc1ccc(CCC(=O)NCc2ccccc2)cc1N +CC(C)n1ncc2cc(C(=O)NCC3CCCO3)cnc21 +CN(Cc1ccc2c(c1)OCO2)C(=O)NCC1CCOC1 +Cc1nc2n(c(=O)c1C)C(CC(=O)Nc1nccs1)CS2 +CN(CC(=O)OCc1ccccc1C(F)(F)F)c1ncccn1 +Cc1ccc(NC(=O)CN2CCN(C(=O)c3ccco3)CC2)cc1F +COC(=O)C1CCCN(Cc2cnc(-c3ccccn3)s2)C1 +O=C(Nc1ccc(Oc2cccnc2)nc1)c1cccc2cc[nH]c12 +CCCCc1ccc2c(c1)C1(OCCO1)C(=O)N2CC +CC1CCCC(NC(=O)COc2ccccc2)C1C +CC(C)NC(=O)c1ccccc1NC(=O)CCc1cccc(F)c1 +CC(C)NC(=O)Nc1cc(C#N)ccc1OC(C)C +CCCSc1nnc2nnc3c4ccccc4[nH]c3n12 +Cc1ccn(CCC(=O)Nc2ccc3nc(C)[nH]c3c2)n1 +COC(=O)CNC(=O)CCOc1cccc(C)c1C +O=C(COC(=O)c1cc(F)c(F)cc1Cl)c1ccc[nH]1 +Nc1ccc2c(Br)cnc(NCc3cccnc3)c2c1 +O=C(COc1ccccc1F)N1CCN(CCn2cccn2)CC1 +O=C(C1OCCc2ccccc21)N(CCO)Cc1ccccc1 +COC(=O)c1cc(-c2ccccn2)nc(N2CCOCC2)n1 +CC1CC(NC(=O)c2c(O)cc(Cl)cc2Cl)CC(C)O1 +O=C(c1ncoc1C1CC1)N1CCCCC1CCn1cccn1 +Cc1cccc(-c2nc(C)nn2CC(=O)NC(C)C)c1 +CC1CCCC(CNC(=O)c2cc3ccccc3c(=O)[nH]2)C1 +Cc1ccc(C(=O)Nc2cccc(S(N)(=O)=O)c2C)o1 +Cc1nc2ccccc2n1CCNc1c(F)cc(C#N)cc1F +CC1CN(C(=O)c2cn(C)nc2C(C)(C)C)CC(C(N)=O)O1 +O=C(OCc1ccc2[nH]c(=O)[nH]c2c1)C1CCCN1 +Cn1cc(C(=O)Nc2ccc3oc(=O)ccc3c2)ccc1=O +COc1ccc(NC(=O)c2ccc(SC)cc2)c(OC)c1 +CCC(O)CN1CCN(C(=O)CCN2CCCC2=O)CC1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccc(N2CCOCC2)nc1 +O=C(Nc1ccc2c(c1)OCCO2)c1n[nH]c2c(Cl)cccc12 +Cc1ncc(-c2nc3c(s2)CC(C)CC3)c(N)n1 +CC(C)n1ncc2cc(NC(=O)N3CCNC(=O)C3)cnc21 +Cc1cccc(NC(=O)c2ccc(S(=O)(=O)NC(C)C)cc2)c1 +CCn1nnnc1SC(C)C(=O)Nc1ccc(C#N)c(Cl)c1 +COC(=O)Nc1ccccc1C(=O)N(C)c1ccc(F)cc1 +CCNc1ncc(C(=O)N(CCO)C2CC2)s1 +C#CCNC(=O)c1cnn(-c2ccc(C(F)(F)F)cn2)c1C(C)C +O=S(=O)(Nc1ccncc1)c1ccc(Cl)c(Cl)c1Cl +CC(=O)c1ccc(NC(=O)N2CCC3OCCCC3C2)cc1C +CC(=O)c1cc(-c2ccc3c(c2)OCCO3)[nH]c1C +Cc1ccc(C(=O)N2CCN(CC(C)O)CC2)cc1 +COc1ccc(NC(=O)N2CCOc3ccccc32)cc1 +COc1ccc(C)cc1NC(=O)c1cncc(N)c1C +N#Cc1cc(F)ccc1NC(=O)c1cccc(-c2ccoc2)c1 +CCOCC12COCC1CN(Cc1csc(C)n1)C2 +Cc1c(C#N)c(NC(=O)Cn2cnc(C#N)n2)n(Cc2ccco2)c1C +CC(=O)N1CCN(C(=O)CN(CCC#N)CCC(F)(F)F)CC1 +NS(=O)(=O)CCNC(=O)c1ccc(Br)cc1 +CSc1ccc(Cl)c(C(=O)N(C)Cc2nnc3ccccn23)c1 +Cc1c(C(=O)NCCNC(=O)CC(C)(C)C)cn2nc[nH]c(=O)c12 +COCCOc1ccc(CNC(=O)N2CCc3sccc3C2)cc1 +CSc1cc(C(=O)Nc2ccc(C)cc2O)ccn1 +CNC(=O)CCNS(=O)(=O)c1ccc(C(C)=O)cc1 +O=C(NCC(c1cccnc1)N1CCOCC1)c1cc(C2CC2)n[nH]1 +O=C(c1ccc(C(F)(F)F)cc1)N1CCCCCC1c1ccncc1 +COCCNC(=O)C1CC2CCN(c3ccc(C)nn3)CC2O1 +O=C(OCc1cnn(-c2ccccc2)n1)C1CCc2cn[nH]c2C1 +CN(C)C(=O)c1cccc2c1CCN2C(=O)c1ccccc1 +CC(=O)NCC(=O)Nc1cc(C(N)=O)ccc1N1CCCCC1C +COC(=O)CC1Nc2cc(Cl)cc(Cl)c2NC1=O +O=S(=O)(NC1CCc2cc(F)ccc21)c1ccccc1F +CC(Cn1cncn1)C(=O)Nc1ncc(Cc2ccc(F)cc2)s1 +Cc1cc(C)c(C#N)c(SCC(=O)Nc2ccccc2C(N)=O)n1 +CCOC(=O)n1c2ccccc2c(=O)n1CCO +COc1ccc(NC(=O)Cc2csc(C(C)C)n2)cc1 +NC(=O)C1(NC(=O)Cc2cn3ccsc3n2)CCCCC1 +Cc1cccc(C(=O)OCC(=O)N2CCCCC2)c1O +CCOc1ccc(CNn2nnnc2N)cc1OC +Nc1ccccc1N1CCN(C(=O)CCc2ccccc2)CC1 +CC(C)CN(C)C(=O)CNC(=O)NCc1ccccc1 +COCCNC(=O)Cn1c(=O)n(-c2ccc(F)cc2)c2ncccc21 +CN(C)C(=O)CN1CCN(C(=O)c2ccc(Cl)cc2Cl)CC1 +CCOc1ncccc1CNC(=O)N(C)Cc1ccc2c(c1)OCO2 +CCN(CC)C(=O)COc1cccc(NC(=O)C2CC3CCC2O3)c1 +COc1ccc(CNC(=O)c2ccc(C(F)(F)F)nc2)cc1OC +Cn1cc(C(=O)NC2CCN(c3ncc(C#N)cc3Cl)CC2)cn1 +CN1CC(C(=O)Oc2ccc(NC(=O)c3cccs3)cc2)CC1=O +CC(C)N1CCN(C(=O)C2CC(=O)N(CCc3ccccc3)C2)CC1 +COc1cc(N)ccc1NC(=O)CCOC1CCCCC1 +Cc1ccc(SCC(=O)NCc2cccnc2)cc1 +CC1CN(CCCNCc2csc(C(C)C)n2)CC(C)O1 +CCOC(=O)Nc1ccc(NC(=O)C(C)OC)cc1 +CSc1ncc(Cl)c(C(=O)OCc2ccc(C(N)=O)cc2)n1 +NC(=O)C(NCc1nn(-c2ccccc2)c2c1CCC2)c1ccccc1 +COc1cc(NC(=O)NCC(=O)Nc2ccc(F)cc2)cc(OC)c1 +O=C(NCCc1cccnc1)c1coc(COc2cccc(F)c2)n1 +Cc1nc(COCC2CC3OCCN(Cc4ccco4)C3C2)cs1 +CCCCNC(=O)NCC(C)N1CCc2ccccc21 +Cc1cc(=O)n(CC(=O)N(C)C2CCCCC2)c(N2CCOCC2)n1 +Cc1nc(SCC(=O)NCC(=O)c2ccccc2)oc1C +CCN(CC)c1nc(C)cc(C(=O)Nc2cnn(CC)c2)n1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCc1ccc(F)cc1 +O=S(=O)(Cc1ccon1)NCC1(c2ccc(F)cc2F)CC1 +Fc1cc2c(cc1Cl)C(c1ccoc1)NCC2 +O=C(NCC1CCCN(C(=O)C2CCOCC2)C1)c1ccc(F)cc1 +CCOC(=O)c1c(C(=O)OCC)c(C)n(C2CC2)c1C +CC(=O)NC(C)(C)c1noc(-c2ccc(F)cc2)n1 +CC(OC(=O)c1ccc(=O)n(Cc2ccccc2)n1)C(N)=O +Cc1ccc(N(CCC#N)C(=O)C(C)Sc2ncn[nH]2)cc1 +CCc1ccc(-n2cnnc2)cc1NC(=O)N1CCC(F)(F)CC1 +CC1(NC(=O)C2(C)CCCO2)Cc2ccccc2C1 +Cc1ccc2c(c1)-c1c(cnn1CC(=O)N(C)Cc1ccco1)CO2 +CCN(CC)c1ncnc2c1ncn2Cc1ccc(C(=O)OC)cc1 +COc1ccc(Nc2ccnc3c(F)cc(F)cc23)cc1OC +CC(C)Oc1ccc(CNS(=O)(=O)c2cc(F)ccc2F)cn1 +CCNC(=O)c1c(C)nc(N)nc1COc1cccc(C)c1 +Cc1noc(C)c1CC(=O)Nc1cccc(Cl)c1Cl +COCCC1(CO)CCCN(C(=O)C2(c3ccccc3F)CC2)C1 +COCCCn1ccc(NC(=O)NCc2scnc2C)n1 +O=S(=O)(NCCc1cccc(Cl)c1Cl)N1CCCCC1 +CCc1c(C(=O)CN(C)Cc2ccc(C)s2)[nH]c(C)c1C(C)=O +Cc1[nH]cc(C(=O)OCC(=O)N2CCCC2)c(=O)c1Br +N#Cc1c(-c2ccnc3ccccc23)cc(-c2ccco2)nc1N +C=CCNC(=O)C1CCN(S(=O)(=O)N(C)C)CC1 +CC(C)CS(=O)(=O)N1CC(S(=O)(=O)c2ccc(F)cc2)C1 +COc1ccccc1C(O)CNc1c(C)cc(C)cc1C +COc1ccc(-c2ccn3nc(N)nc3c2)cc1OC +CC(Sc1n[nH]c(N)n1)C(=O)NCc1ccccc1F +Cc1cc(C(=O)CN(C)C(C)c2cccc(S(N)(=O)=O)c2)c(C)[nH]1 +CN(C)C(=O)c1cc(C(=O)NCC(F)(F)F)ccc1F +O=c1oc(-c2cccs2)nn1Cc1coc(-c2cccs2)n1 +COCCCC1CCCN(C(=O)c2cc(Cl)ccc2C)C1 +O=C(NCc1ccccc1)c1cc(F)ccc1-n1cnnn1 +CC(=O)c1cc(C(=O)C(C#N)c2ccccn2)n(C)c1 +COc1cc(C)ccc1NC(=O)Cn1ccc(=O)n(C)c1=O +CCn1cc(C(=O)NCCc2ccc(C)c(OC)c2)c(C(C)C)n1 +CCOC(C(=O)N1CCN(CC(C)O)CC1)c1ccccc1 +O=c1[nH]c(N(CCO)CCO)nc2sc3c(c12)CCCC3 +Cc1nc(CC(=O)Nc2nc(-c3ccc(F)cc3)ns2)cs1 +O=C(Cc1ccccc1Cl)NCCC(=O)N1CCCC1 +CCOC(=O)c1c(C(F)(F)F)nc2c(C)cccn12 +CCC(NS(C)(=O)=O)c1ccccc1OCC(=O)N1CCCC1 +COc1ccccc1-n1cc(C(=O)Nn2cnnc2)cn1 +CCCCOC(=O)Cn1c(C(C)C)ccc(C#N)c1=O +CCC1CCCN(C(=O)c2ccc(OCc3c(C)noc3C)cc2)C1 +CCCNC(=O)CCNS(=O)(=O)c1c(C)c(C)c(C)c(C)c1C +CC(=O)c1ccc(OCC(=O)Nc2c(C)cc(C)nc2C)cc1 +Cc1ccc2ncc(C(=O)OCc3nc4ccccc4[nH]3)n2c1 +COCCNc1cc(-c2cccnc2)nc(-c2ccccc2)n1 +COc1ccc2c(c1)CCN2C(=O)c1cc2c([nH]c1=O)CCCC2 +Cc1c(C(=O)N2CCN(c3ncccn3)CC2)oc2ccc(F)cc12 +COc1cccc(OCc2nc(-c3cccnc3)no2)c1 +CCn1cc(CNc2ccc(F)c(N3CCCS3(=O)=O)c2)cn1 +O=C(Nc1ccccc1F)N1CCc2sccc2C1 +COc1ccc(C(NC(=O)c2cnns2)C2CCOCC2)cc1 +CCOC(C)c1nccn1CCOc1ccccc1Cl +CCOC(=O)N1CCCC(C(=O)N2CCSc3ccccc32)C1 +Cc1cc(-c2nnc(NC(=O)c3ccccc3)o2)n(C)n1 +CCC(=O)N1CCc2cc(Br)ccc21 +Cc1ccc(OC(C)C(=O)Nc2ccc3c(c2)OCCO3)c(C)c1 +N#Cc1ccc(N2CCN(Cc3nnnn3C3CC3)CC2)c(F)c1 +Cc1ccc(C2COCCN2Cc2cnc(-c3ccsc3)s2)o1 +COC(=O)C(CC(C)C)NC(=O)c1cccc(-n2cnnn2)c1 +CC(=O)N1CCN(C(=O)CCNC(=O)c2ccccc2)CC1 +Cn1nnnc1-c1cccc(C(=O)NCCc2c[nH]c3ccccc23)c1 +Cc1nc(C)c(CNCc2cnc(OCC(C)C)c(Cl)c2)s1 +CN(C)C(=O)C1CCC2(CCN(c3ncccn3)CC2)O1 +C=CCNC(=O)C1CSc2nc(C)c(CC)c(=O)n2C1 +Cc1n[nH]c(Nc2cccc(C(F)(F)F)c2)nc1=O +c1ccc(Cn2cc(-c3n[nH]c4ccccc34)cn2)cc1 +OCCOCCSc1nnc2sc3ccccc3n12 +CCc1cc(N2CCN(c3ccc(C)cc3C)CC2)n2ncnc2n1 +NS(=O)(=O)c1ccc(Br)cc1Br +CCOCCC(=O)NC(C)c1ccccc1OC +CCOC(=O)c1cccc(NC(=O)NCc2csc(NC)n2)c1 +CC(=O)c1ccc(C)c(S(=O)(=O)NCC(C)C)c1 +Cc1nn(CCCNC(=O)c2ccnn2C)c(C)c1Br +C=CCN(Cc1cccs1)CC(O)c1cccc(F)c1 +Nc1cc(CCC(=O)N2CCc3ccccc3C2)ccc1N1CCCC1 +Cc1occc(=O)c1OCc1noc(C(=O)NCCO)n1 +COc1cccc(C2CC(c3ccccc3)Nc3nc(N)nn32)c1 +O=C(CC1C=CCC1)NCCc1c[nH]c2ccccc12 +CCCn1c(NC(=O)CCNC(C)=O)nc2ccccc21 +Cc1ccccc1CNC(=O)C1CCC(=O)N(C)C1c1cccs1 +COc1cc(CCC(=O)Nc2nc(C)c(C)s2)on1 +CCc1nc(CN(C)C(C)c2cccc(S(N)(=O)=O)c2)cs1 +Cc1noc(C)c1CCCNC(=O)C1CCN(C(=O)C2CCC2)CC1 +Cc1nn(C)c(C)c1CCN(C)C(=O)Nc1ccc(Cl)cc1 +Cc1n[nH]c(C)c1C(C)C(=O)N(CC(O)c1ccc(F)cc1)C1CC1 +Cc1n[nH]c(C2CN(C(=O)Cc3csc(C)n3)CCO2)n1 +Cc1cnccc1NC(=O)C(C)(C)c1ccccc1F +CC1CN(C(=O)c2cc3ccccc3c(=O)[nH]2)c2ccccc21 +CCC(CO)NC(=O)c1cn(-c2ccccc2)nc1-c1cccs1 +COc1cccc(C2C(C(=O)Nc3nncs3)CC(=O)N2C)c1 +Cc1cc(=O)n2c(n1)SCC2CC(=O)Nc1ncccc1C +COc1ccc(N2CC(C(=O)Nc3ccnn3C(C)C)CC2=O)cc1 +O=C(CSc1ccccn1)NCc1cccc(Cl)c1 +O=C(COc1cccc(Cl)c1)NCc1nc2ccccc2[nH]1 +CC(COc1ccc(F)cc1)NS(=O)(=O)C(C)C +CN(C)C(=O)c1cccnc1-c1ccc2ncccc2c1 +CC(Cn1cccn1)NC(=O)NC(C)c1ccc2c(c1)OCCCO2 +COc1ccc2[nH]cc(C(=O)c3ccc(Cl)cc3)c(=O)c2c1 +Cn1cc(C(N)=O)cc1C(=O)Oc1cccc(C(=O)NC2CC2)c1 +CN(Cc1ccsc1)C(=O)c1cc2ccccc2[nH]1 +CCN(CCC#N)C(=O)CSc1ccccc1F +CCOC(=O)C(Nc1cccc(N2CCOC2=O)c1)c1ccccc1 +CCCCOc1cccc(NCc2ccccn2)c1 +Cc1noc(C)c1CC(=O)N1C(C)CC2CCCCC21 +O=C(NCCC(F)(F)F)NCc1cn(-c2ccccc2)nn1 +Cc1cc2c(cc1F)CCNC2C(=O)c1cccs1 +CCn1cc(NC(=O)NCCNC(=O)c2cccnc2)c(C)n1 +O=C(c1ccc(=O)[nH]c1)N1CCc2ccccc2C1 +COc1ccc2c(c1)CCCN2C(=O)CN1CCOC(C)C1 +COc1ccc(OC(C)C(=O)N2CCNCC2)cc1 +CCC(CC)C(O)CNC(=O)NC(C)C(=O)N1CCCCC1 +O=C(COCC(F)(F)F)N1CCc2ccc(Br)cc21 +Cc1cc(C#N)ccc1Oc1ncc(Br)cn1 +CCOC(=O)N1CCCC(C(=O)Nc2ccc(C)c(F)c2)C1 +CC(C)CC1COCCN1C(=O)c1cccc(OCC(F)F)n1 +O=C(Cn1cc(-c2ccccc2)nn1)NC1CCCCC1 +COc1c(F)ccc2c1C(c1sc(C)nc1C)NCC2 +Cc1ccc(C(=O)OCc2nnc(-c3cccs3)o2)o1 +Cc1cc(CNC(=O)NC(C)CCc2ccco2)ccc1F +COc1nccc(-c2ccnc3c2ccn3C)c1C#N +CCOC(=O)CS(=O)(=O)N1CCc2ccc(Cl)cc2C1 +Cc1noc(C(C)OC(=O)CCC(=O)c2ccc(C)s2)n1 +O=C(Nc1nnc(-c2ccc3c(c2)OCO3)o1)c1cc2ccccc2o1 +COc1ccc(NC(=O)N2CCCC2C(=O)Nc2ccccc2)cc1 +CS(=O)(=O)NCCSc1ccccc1Br +COC(=O)C1CCN(C(=O)C(OC2CCCC2)c2ccccc2)CC1 +Nc1c2c(nn1-c1ccccc1)CCN(Cc1ccco1)C2 +CCCn1c(=O)c2ccccc2n(CC(=O)NCCC(C)C)c1=O +CC(c1ccc(-n2cncn2)cc1)N(C)CC(O)c1ccccc1 +COc1ncccc1C(=O)NC1(C#N)CCCCC1 +CC(C)CNC(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +N#Cc1ccc(C(F)(F)F)c(NCCn2cnnc2C2CC2)c1 +O=C(CCc1ccco1)Nc1ccccc1N1CCCC1 +CC(Cc1ccsc1)NS(=O)(=O)c1ccc(F)cc1Cl +O=C(NC1CCCCC1)N1CCC(n2cnc3cccnc32)CC1 +CCOc1ccc2ccccc2c1-c1cc(N)[nH]n1 +CCc1nc2ccccc2n1C1CCN(C(=O)Cc2cccnc2)CC1 +CCCOc1cccc(CNC(=O)NCC(=O)NC)c1 +CCOC(=O)C1CCCN(C(=O)CN2CCOCC2C2CC2)C1 +Cc1cnc(NC(=O)CCCc2nc3ccccc3s2)s1 +NC(=O)c1ccc(NC(=O)N2CCOCC2C2CC2)cc1F +CCOc1ccccc1OS(=O)(=O)c1ccc(NC(C)=O)cc1 +CCCN1C(=O)COc2ccc(-c3noc(CNC(C)=O)n3)cc21 +Cc1cc(C)c2oc3nc(N)c(C#N)cc3c(=O)c2c1 +O=C(C1CC1)N1CCC(C(=O)N(CCO)Cc2nccs2)CC1 +Cc1ccc(NC(=O)CCC(C)C#N)cc1Cl +COc1ccc(Cl)cc1S(=O)(=O)NC(CO)C(C)C +CC(C)NC(=O)Nc1ccc(CNC(=O)Nc2cccnc2)cc1 +CCCNC(=O)C(N)c1cccc(Cl)c1Cl +CCCN(CCC)C(=O)C1CC(=O)N(C2CCCC2)C1 +O=C(Cn1cc(Cl)ccc1=O)c1ccc(Cl)cc1 +CCNC(=O)CN(C)S(=O)(=O)c1c(C)cc(C)cc1C +CCCC(=O)NCC(O)c1ccc(OC)c(Cl)c1 +CC1CCCC(CNC(=O)CCCNC(=O)c2ccsc2)C1 +Cc1csc(CNc2ccccc2C(=O)NCC(C)C)n1 +CS(=O)(=O)NCC(O)c1ccc2c(c1)CCCC2 +Cc1ccc(CNc2cc(C(N)=O)ccc2C)cc1 +CCCc1cc(C(=O)NC2CCCc3c2cnn3C)[nH]n1 +CCOC(=O)c1cnc(N2CCC(O)CC2)nc1 +O=C(Nc1cccc(O)c1)c1csc(-c2ccccc2)n1 +CC(Cn1cccn1)NC(=O)c1ccc2ccccc2c1 +O=C(CNC(=O)c1ccccc1)NCCC(=O)N1CCCC1 +Cc1ccc(S(=O)CCC(=O)Nc2ccccc2)nc1 +CCc1ccc(CN(C(=O)c2c(C)c(C)nn(C)c2=O)C2CC2)cc1 +Nn1c(SCC(=O)NCc2cccs2)nnc1C(F)(F)F +CN(Cc1cccc(C#N)c1)C(=O)C1COc2ccc(F)cc2C1 +COC(=O)Cc1ccc(Oc2ccc(N)cc2Cl)cc1 +CC(C)Oc1ccc(NC(=O)NC(CCO)C(C)C)c(F)c1 +Cc1ccc(S(=O)(=O)N(Cc2cccnc2)C2CC2)cc1 +Cc1ccccc1CNC(=O)CSc1ccccc1 +O=C(NC1CCN(C(=O)C2CCC2)C1)C1CCC1 +CCC1CCCCN1C(=O)CN1CCN(c2ccc(C)cc2)C1=O +CN1C(=O)CCCC12CCCN(C(=O)Nc1ccccc1)C2 +CC(=O)N1CCC2(CC1)C(=O)NC2c1ccccc1 +COc1ccccc1Oc1ncccc1CNC(=O)C1CCC(=O)N1 +Cc1nnc(-n2nnc(CO)c2Cc2ccc(F)cc2)s1 +FC(F)(F)c1cccnc1NCCNc1cncc(-n2cccn2)n1 +COC(=O)COc1ccc(S(=O)(=O)Nc2cccc(C#N)c2)cc1 +Nc1c(C(=O)Nc2cccc(Br)c2)sc2ncccc12 +O=C(Cn1cccnc1=O)N1CCCC(CO)(CC2CC2)C1 +Cc1nnc(SCC(=O)Nc2ccc(C(=O)N(C)C)cc2)s1 +Cc1c[nH]nc1C1CCN(S(=O)(=O)c2ccccc2)C1 +O=C(Cc1csc(N2CCCC2=O)n1)Nc1cccc(Cl)c1 +CC(=O)Nc1ccc(SCC(=O)N2CCC(C(N)=O)CC2)cc1 +CCc1nnc2n1NC(c1ccc(C)cc1C)CS2 +CCc1n[nH]c(SCC(=O)c2c[nH]c3ccccc23)n1 +COC(=O)Nc1ccccc1C(=O)NCC(F)(F)F +CC(NC(=O)c1ccccc1)C(=O)Nc1ccc(Br)cc1 +CC(C)(C)c1nnc(CNc2cccc(C#N)c2)o1 +CCN(CCc1ccccc1)C(=O)C(C)NC(C)=O +O=C(COc1ccccc1)N1CCCN(c2ncccc2F)CC1 +O=C(CCc1nc(-c2ccccc2)no1)NCCc1ccccc1 +N#Cc1ccc(S(=O)(=O)N(CCCCO)C2CC2)c(Cl)c1 +COc1ccc2c(CC(=O)Nc3cc(F)cc(F)c3)coc2c1 +Cn1cc(S(=O)(=O)NC2CCCN(Cc3ccccc3)C2=O)cn1 +CC1CCCCC1NC(=O)NC(Cc1ccccc1)C(=O)N(C)C +COc1cc(OC)c2ccn(CCCC#N)c(=O)c2c1 +Cc1ccc(C(=O)Nc2cc3[nH]c(=O)oc3cc2C)cc1 +CCCNC(=O)CNC(=O)CNC(=O)c1ccsc1 +CNC(=O)NC(C)(C)C(=O)N1CC(C)CC(C)C1 +COCCN(CC(C)C)c1ncc(Br)cc1N +CCn1c(=O)c(N2CCC(C(=O)NC(C)C)CC2)nc2ccccc21 +O=C(Oc1ccc2cc(-c3ccccn3)c(=O)oc2c1)C1CC1 +CCOc1cc(NC(=O)c2ccc(F)cc2)c(OCC)cc1N +CSc1ccc(C(=O)NC2CCN(C(=O)c3ccoc3C)CC2)o1 +CCCc1nnc(NC(=O)c2nc(C)sc2-c2ccccc2)s1 +COc1cc(-c2noc(CC#N)n2)ccc1OC(C)C +Cc1ccccc1CNC(=O)N1CCC(NS(C)(=O)=O)CC1 +Cc1cccc(C2NCCc3ccc(Cl)cc32)n1 +COc1nc(C(C)(C)C)nc(NCc2ccc(C)cc2)c1N +Nc1ccc(Cl)c(NC(=O)c2ccc(Br)cc2)c1 +CCCCc1cc(=O)oc2cc(OC(C)=O)ccc12 +O=C(NCc1cccc(OC2CCCC2)c1)c1ccc2ncnn2c1 +CC1Cc2ccccc2N1C(=O)c1csc(-c2ncccn2)n1 +Cc1cccc(C)c1NC(=O)N1CCC(n2ccnn2)CC1 +CC(C)c1ccc(NS(=O)(=O)c2coc(C(N)=O)c2)cc1 +CNc1ncc(C(=O)NCCNC(C)=O)cc1Cl +Cc1nn(CC(=O)NC2CCCC2)c(=O)c2cc3sccc3n12 +CCN(C(=O)c1cc(OC)c(S(N)(=O)=O)s1)c1ccccc1 +CC(=O)N1CCCc2cc(S(=O)(=O)Nc3ccccn3)ccc21 +Cc1ccccc1C(=O)N1CCc2nc3cccc(C)n3c(=O)c2C1 +CCNC(=O)CNC(=O)c1cc(C2CC2)n(C(C)(C)C)n1 +CC1CN(Cc2nnc(-c3cccc(Br)c3)o2)CCO1 +Cc1ccc(C#N)c(=O)n1CC(=O)NCC1CCCO1 +COc1ccc(-n2ccc(CNC(=O)N3CCCC3)n2)cc1 +C=CCNS(=O)(=O)c1ccc(OCC)c(-c2nc(C)no2)c1 +CCn1nc(C)c(CN(CCOC)C(=O)c2cnc(C)c(C)c2)c1C +CC(C)Oc1cncc(C(=O)NCC(C)(C)c2ccncc2)c1 +CCc1ccc(S(=O)(=O)N(Cc2ccco2)CC2CCCO2)cc1 +COc1ccc(-c2nnc(NCc3ccsc3)o2)cc1OC +CC(=O)Oc1ccc2c(C)c(Cl)c(=O)oc2c1 +Cc1c(Cl)cccc1NC(=O)c1ccc(N2CCCC2=O)cc1 +CCNC(=O)c1c(NC(=O)CC#N)sc2c1CCCC2 +CCSc1ccccc1C(=O)Nc1nccc(C)n1 +Cc1nn(C)cc1CN(C)S(=O)(=O)c1c(C)c(C)c(C)c(C)c1C +COc1c(C)cnc(CNC(=O)c2cc(Br)c[nH]2)c1C +CC(=O)Nc1cccc(NC(=O)COc2ccc(C(C)C)c(C)c2)c1 +CCNC(=O)CN(CC)C(=O)COc1cc(Cl)cc(Cl)c1 +Cc1cc(C(=O)CNC(=O)c2ccc(Cl)cc2)ccc1F +Cc1ccc(CCOC(=O)c2ccc(C#N)cn2)cc1 +Cc1ccc(C(=O)N2CCOC(c3cccc(OC(F)F)c3)C2)cn1 +O=C(Nc1ccc2ccccc2c1)c1ccc(-n2ccnn2)cc1 +Cc1noc(C)c1C(C)NC(=O)c1ccccc1F +CCC(C)NC(=O)c1cc(-n2cnnc2)ncc1Br +CC(C)C(C)n1ncc(S(=O)(=O)NC2CC2)c1N +Cc1nc(C(=O)Nc2ccn(CC(N)=O)n2)cs1 +O=C(Nc1cccc(Cl)c1)NC1CC(=O)N(c2cccc(F)c2)C1 +O=C(NC(C(=O)c1ccccc1)n1cnccc1=O)c1ccccc1 +COc1ccc(C2c3c(C)n[nH]c3Oc3[nH]c(=O)c(C#N)c(N)c32)cc1 +Cc1c(C(=O)NCCCn2cccn2)oc2c1C(=O)CC(C)(C)C2 +CC(=O)N1Cc2ccccc2CC1C(=O)N(C)Cc1cccnc1 +O=C(NCc1cn2ccccc2n1)NCC1CCC1 +Cc1ocnc1CNC(=O)Nc1ccc(F)cc1OC(F)F +Cc1occc1C(=O)Nc1ccnc2cc(Cl)ccc12 +CC(C)C(NC(N)=O)C(=O)NCC1(Sc2ccccc2)CCCC1 +Cc1cc(C(=O)Nc2nccs2)c(C)n1C1CCCCC1 +Cc1noc(C2CN(C(=O)c3cccc(N(C)C)c3)C2)n1 +Cc1ccnc(NC(=O)c2cccc(OCc3nnnn3C)c2)c1 +N#CCCCn1c(-c2ccc3c(c2)OCO3)nc2ccccc21 +Cc1ccc(C2(O)CCN(C(=O)C3CCC3)CC2)cc1 +COCC(=O)N(C)CC(=O)Nc1ccccc1C(=O)C(C)C +CSc1cccc(NC(=O)c2ccncc2F)c1 +CC(=O)Nc1cccc(CNC(=O)N(Cc2ccc(C)o2)C(C)C)c1 +CC(C)Oc1ccc(Nc2ncccc2CO)cc1 +Cc1noc(C)c1N(C)CC(=O)N1CCCCC1C +Cc1nc(C)c(C(C)Nc2cccc(F)c2)c(=O)[nH]1 +CC(C)Cc1nn2c(C#N)c(-c3cccnc3)nc2s1 +Cc1c(N)cccc1S(=O)(=O)N(C)Cc1ccco1 +Cc1ccc(OCC(=O)NCc2ccccc2Cn2ccnc2)c(C)c1 +Cc1nn(C)c(C)c1OS(=O)(=O)c1ccc(Cl)c(C#N)c1 +CN(C)c1ncccc1NC(=O)c1ccc(C#N)cc1 +NS(=O)(=O)c1ccc(NC(=O)c2cscn2)cc1F +COC(=O)c1ccccc1Oc1nc(C)cc(C)n1 +CC1CCCC(C)N1C(=O)NCCCN1CCCCCC1=O +CCN(CC)C(=O)CSc1ccc(N)cc1Cl +CCOC(=O)NC(C(=O)Nc1nnc(CC)s1)C(C)C +CC(C)Cn1c(N2CCCC2)nc2c1c(=O)[nH]c(=O)n2C +CCOCCn1c(CNC(=O)C2CCCCC2)nc2ccccc21 +N#Cc1ccc(S(=O)(=O)NCC(O)c2ccccc2Cl)cc1 +CCC(C)OC(=O)Cc1csc(NC(=O)c2ccccc2)n1 +CCCC12CN3CC(C)(CN(C1)C3c1c(C)[nH]c(=O)[nH]c1=O)C2=O +CCC(=O)N(C)CCCNC(=O)c1nc2ccccc2c(=O)[nH]1 +O=C(Nc1cccnc1)C1CC2CCN(c3nncs3)CC2O1 +O=C(Cc1ccc(F)cc1)NCCOc1ccc(-c2ccco2)nn1 +O=C1OCCC1Sc1nnnn1Cc1ccco1 +CN(CCO)S(=O)(=O)c1ccc(C(=O)NC2CCCCC2)cc1 +CCCc1nc(NCc2ccc(Cl)cc2)c(N)c(OC)n1 +CCCCc1nnc(NC(=O)C2CCCN(C(N)=O)C2)s1 +COCC1CCCN1C(=O)c1csc(C(C)=O)c1 +Cc1n[nH]c(C)c1C1CCCCCN1C(=O)NCc1ncccc1F +CN(C)S(=O)(=O)N1CCN(CC(O)c2ccc(F)cc2)CC1 +CCc1noc(C)c1C(=O)N1CC(C(=O)N2CCN(C)CC2)C1 +CCCCCC1CC(COc2ccccc2)OC1=O +COc1ccc(Cl)c(NC(=O)N(C)C(C)c2cccnc2)c1 +CCCSc1nnc2c3cc(F)ccc3n(C)c2n1 +CCCCNC(=O)CCN1C(=O)COc2ccccc21 +Cc1ccc(NC(=O)N(Cc2ccncc2)CC2CCCO2)cc1 +CCN(C(=O)c1cc[nH]n1)C1C2CC3CC(C2)CC1C3 +Cc1nsc(N2CCN(CC3=Cc4ccccc4OC3)CC2)n1 +CC(C)c1cc(C(=O)Nc2ccc3c(c2)COC3)n(C)n1 +N#Cc1cn(C2CC2)c(=O)n(CC(O)c2ccccc2F)c1=O +COc1ccnc(NC(=O)c2cccc(-c3n[nH]c(C)n3)c2)c1 +COc1ccc(C(=O)NCc2ccc(F)cc2)c(OC)c1 +COc1cccc(C(=O)NCc2cccc(C(N)=O)c2)c1O +CCCC(NC(=O)Cc1ccc(F)cc1F)c1nnc2ccccn12 +CCCC(=O)N1CCCC1C(=O)N(C)CC(=O)NC(C)C +OCC(CNc1ncc(Cl)cc1F)Cc1ccccn1 +Cc1ccc(OCC(=O)NCC2CCCO2)cc1C +Cc1nc(CNC(=O)CCN2CCOC2=O)cs1 +O=C1CSc2nc(C(Cl)(Cl)Cl)nn21 +COc1cccc2c1CCCCN2C(=O)c1ccoc1 +Cc1cc(C)n(C(C)C(=O)N(C)Cc2c[nH]nc2-c2ccccc2)n1 +O=C(CCC(=O)c1ccccc1)Nc1ccc2c(c1)OCCO2 +O=C(c1nc2ncccn2n1)N(C1CCCCC1)C1CCCCC1 +O=C(Nc1cccnc1N1CCOCC1)c1ccc(Cl)cc1F +CC(C)NC(=O)CN(C)c1nc2sccn2c1CO +CC=Cc1ccc(OC(=O)c2cccn2C)c(OC)c1 +O=C(Nc1ccccc1N1CCCC1)c1cccc(F)c1 +CC(CN1CCN(c2ccccc2)CC1)NC(=O)Cc1ccc[nH]1 +COC(=O)CCCn1cnc2sc3c(c2c1=O)CCC3 +O=C(c1ccccn1)N1CCn2cnc(COCC3CC3)c2C1 +COc1ccc(CC(=O)N2CC(OCc3cccc(F)c3)C2)cc1 +CCCn1c(SCCC#N)nc2cc(S(N)(=O)=O)ccc21 +O=C(Nc1cn[nH]c1)c1[nH]c2ccc(Br)cc2c1Cl +Cc1ccc(C(=O)N(C)C)cc1OC(=O)C1CC2CCC1O2 +Cc1nc[nH]c1-c1nccn1CC1(N2CCOCC2)CCCCC1 +CCNC(=O)Nc1cccc(NS(=O)(=O)c2cc(C)ccc2C)c1 +COC(=O)c1sccc1CN1CCOC(c2ccccc2C)C1 +COc1ccc(C(C)(C)C)cc1C(O)CCC(=O)N(C)C +CN1CCC2(CCCN(C(=O)c3ccnnc3)C2)C1=O +O=C(NCc1ccccc1F)c1cccc(N2CCCS2(=O)=O)c1 +O=C(NCc1cnn(Cc2ccccc2)c1)NCc1ccccn1 +Cc1cc(C(F)(F)F)nn1CC(=O)N1CCc2ccccc2C1 +CC(C)c1ccc(C(C#N)N(C)C(=O)c2cccnc2)cc1 +O=C(CCc1csc(NC(=O)c2ccco2)n1)Nc1nccs1 +CCNC(=O)C1CCN(C(=O)c2ccsc2)CC1 +COc1ccc(NC(=O)NCc2cnn(C)c2)cc1Cl +O=C(NC1CC1)c1cc(NC(=O)N2CCCC2)ccc1Cl +O=C1C=C(c2cc(F)ccc2O)Nc2ccccc2N1 +COC(=O)CC1CN(Cc2cnn(-c3ccccc3)c2)CCO1 +CCOc1cc(S(=O)(=O)n2nccc2C)ccc1F +COCCn1cc(CC(=O)Nc2ccc(OC)nc2)c2ccccc21 +CC(C)CN(C)C(=O)Nc1ccccc1-n1cccn1 +CCNc1ncc(C(=O)NCCCc2ccncc2)cn1 +c1ccc(-c2noc(-c3ccc(N4CCOCC4)nn3)n2)cc1 +O=C(NCc1cccs1)C1CCN(C(=O)c2ccc(F)cc2)CC1 +COCCN(Cc1ccc(C)o1)C(=O)Nc1ccc(F)cc1C +CCCCCNC(=O)c1ccc(=O)n(CCC)n1 +Cc1c(C(=O)NC(C)CO)sc2nc3n(c(=O)c12)CCCCC3 +CCOc1ccc(C(=O)Nc2nccs2)cc1Br +Cn1nncc1CNc1cnn(-c2cccc(C(F)(F)F)c2)c1 +COC(=O)N1CCC(OC(=O)C(C)N2CCc3ccccc3C2)CC1 +Nc1cc(CCC(=O)N2CCCc3ccccc32)ccc1N1CCCC1 +CC(=O)N1CCc2c(sc(NC(=O)c3ccc(F)cc3)c2C#N)C1 +CCN1C(=O)Cc2cc(NC(=O)c3cc(-c4ccccc4)on3)ccc21 +COC(=O)C1(N(C)C(=O)c2cccc3cn[nH]c23)CCCCC1 +O=S(=O)(c1ccc(Cl)cc1)N1CCC2(CC1)OCCO2 +COCCc1nsc(NCc2ccnn2C)n1 +Cc1c[nH]c(CN2CCOC(c3ccc(F)cc3)C2)c(C)c1=O +Cc1ccc(C(=O)Cn2c3ccccc3n3nc(C)nc23)cc1 +Cc1nc2ccc(-c3ccccc3Cl)cc2c(=O)[nH]1 +N#Cc1c(F)cccc1Oc1ccc(C(=O)N2CCCC(O)C2)cc1 +CC(CN1CCOCC1)NC(=O)c1ccc(-c2ccccc2)[nH]c1=O +CCOC(=O)Cn1nc(C)c(NC(=O)c2ccc3c(c2)OCO3)c1C +O=C(C1CCCN1C(=O)C1CC1)N(Cc1cccc(F)c1)C1CC1 +COC(=O)C(C)C(NCc1ccon1)c1ccccc1 +COc1ccccc1OC1CN(c2nccnc2OC)C1 +O=C(CCC1NC(=O)N(Cc2ccccc2)C1=O)NCc1ccco1 +Cc1noc(-c2cccc(OCC(=O)NCc3ccco3)c2)n1 +O=C(Nc1cc[nH]n1)C1CC(=O)N(C2CCCC2)C1 +Cn1cc(NC(=O)c2cnc(Cc3ccccc3)s2)cn1 +COc1ccc(NC(=O)CSc2ccc(NC(C)=O)nn2)cc1 +c1c(-c2nnc(CN3CCOCC3)o2)sc2c1CCCC2 +CC1Oc2ccccc2N(CC(=O)OC2CCCCC2)C1=O +CC(C)(C)OC(=O)N1CCN(CC(=O)c2ccc(Cl)cc2)CC1 +Cc1nc2cc(O)nn2c(C)c1CCC(=O)NC(C)c1ccccc1 +Cc1ccnc(NS(=O)(=O)c2ccc(C(C)C)cc2)n1 +COc1ccc(NC(=O)Cc2ccccc2O)cc1 +CC(=O)N1CCCN(C(=O)c2cc(C)n(-c3cc(C)on3)c2C)CC1 +Cn1c(S(=O)(=O)Cc2ccc(Cl)cc2)n[nH]c1=O +CCc1onc(C)c1NC(=O)CSc1ccccc1C +CN(Cc1ccco1)C(=O)Nc1ccc(Cn2cccn2)cc1 +CC1CCCCN1C(=O)Cn1nc(-c2ccco2)cc(N)c1=O +COc1ccc(OC)c(C2CCCN2S(=O)(=O)N(C)C(C)C)c1 +Cc1ccc(-c2nnc(NC(=O)CCc3cnn(C)c3)s2)c(C)c1 +O=C(CSc1nn2cnnc2s1)N1CCCCCC1 +CCn1cc(S(=O)(=O)NCCc2ccc(F)cc2)cn1 +CCC(C)Nc1nc(OC)nc(Oc2ccc(=O)[nH]n2)n1 +COc1ccnc(NC(=O)CCCOc2cccc(F)c2)c1 +CC(=O)NC(C)C(=O)Nc1cccc(C(=O)NC(C)(C)C)c1 +Cc1cc(C)n(CC2CCCN2C(=O)c2cnn(C)c2C2CC2)n1 +Nc1ccccc1C(=O)NCCNC(=O)c1cnccn1 +CC1(NC(=O)c2ccc(N3CCCC3=O)cc2)Cc2ccccc2C1 +Cn1nc(C(=O)NCc2cccc(CN3CCOCC3)c2)ccc1=O +Cc1ccc2cc(C(=O)N3CCCCC3Cn3cccn3)[nH]c2c1 +COCC(O)CN(C)C(=O)c1ccc(C)c(N)c1 +Cc1nc2c3ccccc3nn2c(C)c1CC(=O)NCCO +COc1ccc(CNC(=O)c2nc(-c3cccs3)no2)cc1 +CCCc1cc(NC(CO)c2ccccc2)ncn1 +Cn1cc(C(=O)Nc2ccc3c(c2)OCO3)c(C(C)(C)C)n1 +Cn1cc(C(=O)NC(c2ccc(F)cc2)C2CCCO2)cn1 +CCOCc1c(C(=O)N2CCNC(=O)C2)oc2ccccc12 +COC(=O)c1ccc(OC(=O)Cc2cccc(F)c2)cc1 +COc1cccc(COc2ccc(N(C)C(C)=O)cc2)c1 +CCCOCC(=O)Nc1ccc(C(=O)N2CC(C)OC(C)C2)cc1 +Cc1cnn(CC(=O)N2CCOC(c3nc(C)n[nH]3)C2)c1 +CCC(C)(CC)NC(=O)c1ccc(S(=O)(=O)NC)cc1 +Cc1c(Cl)cccc1S(=O)(=O)NC(C)(CC(C)C)C(N)=O +Cc1cc(C(=O)Nc2ccncc2Cl)sc1C +O=C(c1ccc2c(c1)CCO2)N1CCC2(CC1)OCCO2 +COc1cc(OC)cc(C(=O)N(CC(C)O)C(C)(C)CO)c1 +Cc1n[nH]c(C)c1NC(=O)COc1cccc2c1OC(C)(C)C2 +CC(=O)c1ccc(NC(=O)c2cccc(-n3cccc3)c2)cc1 +CC(NC(=O)Cn1cnnn1)c1ccc(Cl)cc1 +CC1Oc2ccccc2N(CCC(=O)NCCc2ccsc2)C1=O +Cc1n[nH]c(N)c1C(=O)N(C)c1cccc(C#N)c1 +O=S(=O)(c1ccc(SCc2ccccn2)nc1)N1CCCCC1 +COCc1ccc(C(=O)N2CCc3ccc(Br)cc32)o1 +CN1C(=O)C(C)(C(=O)Nc2ccccc2F)Sc2ccccc21 +Cn1cnc(S(=O)(=O)N2CCC(O)C2Cc2ccncc2)c1 +CC(CC#N)N(C)C(=O)Nc1ccc(OCC(=O)N(C)C)cc1 +CC(=O)N(C)CC(=O)Oc1cccc(C(=O)NC2CC2)c1 +COc1ccc(NC(=O)c2ccsc2)cc1OC(F)F +COc1ccc(CCC(=O)Nc2ccc(C(C)=O)cc2)cc1N +CCN(CC)C(=O)CSc1nc(C)cc(N)n1 +CNC(=O)NC(C)(C)C(=O)Nc1ccc(Cl)c(Cl)c1 +COCCn1c(N)c(NCc2cn[nH]c2)c(=O)[nH]c1=O +CCCn1cc(NC(=O)Cc2ccc(C)s2)ccc1=O +CCC(=O)N1CCc2cc(CNC(=O)C3CC3)ccc21 +Cc1nc(C2CCCN2C(=O)c2ccc(N3CCCC3)c(F)c2)no1 +Cc1noc(C)c1CNc1ccc(Cl)cc1C(N)=O +C#CCNC(=O)COc1c(Cl)cccc1Cl +CCc1ccccc1CNC(=O)CNC(=O)c1cccs1 +Cc1ccc(C(=O)NCCCCN2CCOCC2)c(=O)[nH]1 +CN(CC(=O)OCC(=O)N1CCCC1)C(=O)c1cccs1 +Cc1ccc2c(C(=O)N(C)C(C)C)cc(-c3cnn(C)c3)nc2c1C +Cc1c(NC(=O)CC2C=CCC2)c(=O)n(-c2ccccc2)n1C +CC(C)C(=O)N1CCCC1C(=O)Nc1cccn(C)c1=O +O=C(NCc1cccnc1)c1ccccc1-c1ccccc1 +CC(C)COc1cccc(-c2cnn(C)c(=O)c2CC#N)c1 +Cc1cc(C(=O)OCC(=O)N2CC(C)CC(C)C2)c(C)o1 +CNc1ncc(C(=O)N2CC(CO)C(CN3CCOCC3)C2)cn1 +Cn1cc(C#N)c(=O)n(Cc2csc(-c3ccccc3)n2)c1=O +CN(C)C(=O)CS(=O)(=O)c1ccc2ccccc2c1 +Oc1cc(Cl)c2c(c1)C(Cc1cccnc1)NCC2 +CCOC(=O)C(C)NC(=O)c1ccc2c(c1)CCO2 +COCc1nnc2sc(-c3cccc(N)c3)nn12 +CCCCC(=O)Nc1nc(-c2c[nH]c(C(=O)OC)c2)cs1 +Cc1cc(Cl)ccc1NC(=O)c1nc(C)n2c1CCCC2 +CCOc1ccc(NC(=O)c2cc(C)cc(C)n2)cc1 +CCOc1ccccc1NC(=O)Cn1cnc2c(cnn2C)c1=O +COc1cccc(OCC(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +CN1CC2(CCC1=O)CCN(C(=O)C1CCC(O)CC1)CC2 +Cc1ccc2c(c1)NC1(CCCC1)CN2CCC#N +Oc1cccc(CN2CCN(c3ccc4nnnn4n3)CC2)c1 +CCS(=O)(=O)N(C)CCCNC(=O)c1ccc(F)c(F)c1 +Cc1c(C)n(C(=O)CSc2nnc3ncccn23)c2ccccc12 +Cc1cc(Cl)ccc1OC(C)C(=O)NCCCN1CCOCC1 +Cc1ccc(NC(=O)c2cncc(N)c2)cc1Cl +CCCn1cc(-c2ccncc2)cc1C(=O)Nc1ccc2c(c1)OCO2 +Cc1ccc(C(=O)Nc2cc(F)cc(F)c2)cc1N +CS(=O)(=O)N1CCC(C(=O)NCCc2ccsc2)CC1 +CN1CC(C(=O)NC2CCN(C(=O)c3ccco3)CC2)CC1=O +COCCCNc1oc(-c2ccc(F)cc2)nc1C#N +COc1cccc(CNC(=O)CSc2ccc3ccccc3n2)c1 +NC(=O)C1CCCN(C(=O)CCn2cnc3ccccc3c2=O)C1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)NC(C)C +CSc1cccc(-c2nnc(NC(=O)c3ccccc3F)o2)c1 +Cc1c(C(=O)NCc2ccoc2)oc2ccc(Cl)cc12 +N#CC1(C(=O)NCC2(C(N)=O)CCOCC2)CCCC1 +CC(Sc1ccccn1)C(=O)N1CCSc2ccccc21 +O=C(NCCNc1cnccn1)c1ccc(Cl)cc1 +Cc1ccccc1-c1noc(Cn2cnc3ccccc3c2=O)n1 +O=C(NCC(F)(F)F)Nc1cccc2[nH]ccc12 +CCn1c(SCC(=O)Oc2ccccc2)nc2ccccc2c1=O +COc1ccc(-n2nnc(-c3ccccc3OC)c2N)cc1 +CCOc1cc(S(=O)(=O)NCc2cccs2)c(C)cc1C +COc1cc2cc(C(=O)N(C)Cc3ccccc3)[nH]c2cc1OC +Cc1nc(C)c(CCC(=O)Nc2cc(F)ccc2C)c(=O)[nH]1 +COc1cc(NC(=O)Cc2ccc(C)cc2)cc(OC)c1OC +O=C(NCc1nncn1C1CC1)Nc1cccc(SC(F)F)c1 +COc1ccc(NS(=O)(=O)c2cccc(C(C)=O)c2)cc1 +O=C(NC1CCCN(Cc2ccccc2)C1=O)C1CC=CC1 +COc1ccc(Cl)cc1-n1ncc(C(C)=O)c1C +CC1CN(C(=O)Cc2c[nH]c3ccccc23)C(C)CO1 +Cc1ccncc1NC(=O)NCC(C)N(C)c1ccccc1 +CCOC(C)c1noc(COc2cccc(S(C)(=O)=O)c2)n1 +CSc1ccc(C(=O)N(C)Cc2ccc(C)cc2)cc1 +OCc1ccc(C2NCCc3c2cc(F)c(F)c3F)cc1 +CCNC(=O)CCC(O)c1ccc(C(C)(C)C)cc1 +CN(C)C(C)(C(N)=O)c1cccc(Br)c1 +COc1ccc(-c2nnc(N3CCC(C(=O)NC(C)C)CC3)o2)cc1 +O=C(CCSc1nncn1CC(F)(F)F)Nc1ccccc1 +CCOc1cc(F)ccc1NCC(=O)Nc1c(C)nn(C)c1C +Cc1ccc(NC(=O)C(c2ccccc2)N2CCOCC2)cc1 +NC(=O)c1ccc(NC(=O)C2(c3ccc(F)cc3)CCOCC2)cc1 +COc1ccc(Br)c(CNC(=O)N2CCOC(C)C2)c1 +Cc1cc(CNC(=O)Nc2ccc(CC(=O)NC(C)C)cc2)c(C)o1 +O=C(NCc1nc(-c2ccccc2)cs1)c1cnccn1 +Cc1c(C(=O)OCc2ccc(C#N)cc2)cnn1C +Cc1cccc(CNS(=O)(=O)c2ccc(Br)cc2)n1 +Cc1cc(F)ccc1NC(=O)CCc1nc(C(C)C)no1 +O=C(NCC1CC1)c1cc(-c2ccccc2)nc2ncccc12 +O=C(CS(=O)(=O)c1ccccc1)Nc1ccccc1Cl +CC1Oc2ccccc2N(Cc2ccccc2F)C1=O +CCSc1ccccc1C(=O)NCc1ccncc1 +CNc1ccc(S(C)(=O)=O)cc1S(=O)(=O)NC1CC1 +CN(C)c1ccccc1NC(=O)NCc1ncc(-c2ccccc2)o1 +CC(NC(=O)CCc1cccc(OC2CCCC2)c1)c1nncn1C +Cn1ccc(NC(=O)c2cc(-c3ccncc3)nc3ccccc23)n1 +CCN(CC(C)C)C(=O)c1ccn(-c2ccc(OC)cc2)n1 +CCOC(=O)c1c(NC(=O)c2ccco2)sc2c1CC(C)CC2 +CCC(NC(=O)NCCCOC)c1cccs1 +Cc1cc(F)cc(NC(=O)NCc2ccccc2)c1 +Cn1cc(C(=O)NCCCNc2ccccc2)c(C(C)(C)C)n1 +CCNC(=O)CN(CC)C(=O)c1ccccc1-c1ccccc1C#N +CCOC(=O)c1nn(-c2nc3ccccc3[nH]2)c(N)c1C +O=C(OC(Cn1cncn1)c1ccc(Cl)cc1)c1cncc(F)c1 +COc1ccccc1S(=O)(=O)NC1CCCCC1O +Cn1nc(C2CCC2)cc1NC(=O)C1CC2C=CC1C2 +CCC(C)C(NC(=O)c1cccc(-n2cccc2)c1)C(N)=O +Cc1c(CCC(=O)Nc2ccc(-c3ccccc3)nn2)cnn1C +CCc1onc(C)c1NC(=O)N(Cc1ccc(C)s1)C(C)C +CC(C)c1ccc(NC(=O)CS(=O)(=O)c2ccccc2)cc1 +CCC(Nc1nccc(C2CCCC2)n1)c1ccncc1 +CC1CCN(C(=O)COC(=O)c2ccc(F)c(Cl)c2)CC1 +CC1CCc2sc(C(=O)NCc3ccccn3)cc2C1 +COc1ccc(-c2nnc3sc(SC)nn3c2=O)cc1 +C=C(C)COc1cccc(C(=O)NC(CO)c2ccccc2)c1 +O=C(CO)Nc1ccccc1NCC1CCCCC1 +COCCNC(=O)Cn1c2ccccc2c2nc(=O)cc(C)n21 +CCCCCNC(=O)c1[nH]c2c(c1C)C(=O)CCC2 +Cc1ccc(C)c(NS(=O)(=O)c2ccccc2N)c1 +COCCNC(=O)CN1C(=O)C(C)Oc2ccc(C(C)=O)cc21 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)c1ccc2c(c1)CCC2 +O=C(NCC1CCOCO1)c1cccc(Cl)c1 +CC(C)C(NC(N)=O)C(=O)NCc1cccnc1OC1CCCC1 +COc1ccccc1CN(C)C(=O)c1cccc(S(C)(=O)=O)c1 +CS(=O)(=O)N1CCC(C(=O)N(Cc2ccncc2)C2CC2)CC1 +COc1cccc(C(NCC(F)(F)F)C(N)=O)c1OC +Cc1ccc2nnc(C(=O)Nc3ccc(F)cc3)n2n1 +COCc1ccccc1C(=O)NCC(C1CCOC1)N1CCOCC1 +CCCCN(CC(F)(F)F)C(=O)c1sc(-c2nc[nH]n2)nc1C +Cn1nc(C(=O)Nc2cccc(Cl)c2)c(=O)c2cc(Cl)ccc21 +Cc1ncc(CNC(=O)Nc2cc(-c3ncco3)ccc2C)s1 +CCCN(CCC)C(=O)c1ccc(NC(=O)c2ccncc2F)cc1 +Cc1ccccc1OCC(=O)NC(C)c1ccc(-n2ccnc2)cc1 +CCCN(CCC)C(=O)c1c(F)ccc(OCC)c1F +CCCCOc1ccc(C(=O)Nc2cc(C)no2)cc1 +O=c1sc2c(n1Cc1nnc(-c3cccc(Cl)c3)o1)CCCC2 +Cc1nnnn1CCC(=O)N1CCn2c(C(N)=O)cnc2C1 +O=C1CN(C(=O)CCC(=O)N2CCN(c3ccccc3)CC2)CCN1 +CCc1sc(C(=O)OCC2CC(=O)N(C3CC3)C2)cc1C +CCOc1ccc(F)c(C(=O)NCCCC(N)=O)c1F +CCSc1nnc(NCc2cccc(O)c2)s1 +C=CCNC(=O)c1cccc(S(=O)(=O)NCc2cscn2)c1 +Cc1nc(C(=O)N2CCCC(C(=O)c3nccn3C)C2)c(C)o1 +CCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)C(C)(C)C +COc1cc(CCC(=O)Nc2nc(C)no2)cc(OC)c1 +CC1CCC(NC(=O)Cc2ccc(N3CCCC3=O)cc2)CC1 +CN(C)S(=O)(=O)c1c[nH]c(-c2nnc(-c3cccs3)o2)c1 +Cc1noc(C)c1C(=O)NC(C)c1cnn(-c2ccccc2)c1C +O=C(Nc1ccccc1)c1ccc(S(=O)(=O)NC2CCCC2)cc1 +CCN(C(=O)c1ccc2c(c1)OCO2)c1ccc(F)cc1 +COc1ccc(CN(C)C(=O)Nc2ccc3c(c2)COC3)c(OC)c1 +COc1cc(NC(=O)c2ccccc2Cl)c2ncccc2c1 +Oc1ccc(C2NCCc3cc(Cl)c(O)cc32)cc1 +COc1ccc(CCNC(C#N)c2ccc(F)cc2)cc1 +CN(Cc1ccc(C#N)cc1)S(=O)(=O)c1cn[nH]c1 +NC(=O)c1c(NC(=O)c2cscn2)sc2c1CCCC2 +Cc1nn(C)c(C)c1NC(=O)C(C)OC(=O)c1cccs1 +Nc1cccc(-c2csc(-c3cccs3)n2)c1 +CCN(CC1CCCO1)C(=O)NCC(F)(F)F +Clc1ccc2c(c1)CN(Cc1ccncc1)CC2 +COc1ccccc1N1CCN(C(=O)Nc2cccn(C)c2=O)CC1 +CCCn1c(=O)[nH]c2sc3c(c2c1=O)CCN(C(=O)CC(C)C)C3 +Cc1ccc2c(c1)NC(C)CN2CC(=O)NCc1ccco1 +COc1cc(F)ccc1Nc1cc(N)cc(F)c1 +Cn1c(=O)ccn(CC(=O)NCc2ccccn2)c1=O +Cc1cccc(N2CCN(C(=O)c3nccnc3N)CC2)c1C +O=C(CCn1cnnn1)N1CC(CO)CC(CN2CCOCC2)C1 +COc1ccc(NC(=O)c2c[nH]c3cccc(F)c23)cc1OC +CC(=O)Nc1ccc(-n2cnc3c(C)ncnc32)cc1 +CN(Cc1cccc(C#N)c1)C(=O)Nc1cccc(C(=O)NC2CC2)c1 +Cc1cc(=O)n(CC(=O)N2CCCCCC2)c2ccccc12 +COc1ccccc1CNC(=O)c1ccc(-c2cccs2)nc1 +CC1(C)CS(=O)(=O)N(Cc2ccc(Cl)cc2)C1=O +Cc1nc(N)cc(N(C)CC2(CO)CCCC2)n1 +N#Cc1ccc(C(=O)NCc2nc3ccccc3s2)cc1 +COc1ccccc1CNC(=O)c1ccc(C)nc1 +COc1ccc(OCc2nc(CN)cc(=O)[nH]2)cc1 +O=C(Nc1cc[nH]n1)c1ccc(-n2ccnn2)cc1 +Cc1nc(C2(NC(=O)NCC3CN4CCCCC4CO3)CCC2)no1 +COc1cc2c(cc1OC)C(C)OC(c1ccc(OC(C)=O)cc1)=C2 +Cc1nc(CNCCc2ccccc2F)sc1C +CCOC(C)c1nccn1CC(=O)N1CCCCCC1 +COc1ccc(CNC(=O)c2cc(Cl)cc(Cl)c2)cn1 +Cc1ccncc1NC(=O)N(C)CCc1ccccc1 +Cn1ncc2c(Nc3ccccc3Br)ncnc21 +CCOc1ccc(-c2cc(C(=O)OC(C)C)[nH]n2)cc1OC +O=C(NCCN1CCOCC1)N1CCN(c2ccccc2F)CC1 +CC(=O)NCC(OC(=O)c1ccc2c(c1)ncn2C)c1ccccc1 +O=C(CCc1cnccn1)N1CCCC(Nc2ccc(F)c(F)c2)C1 +Cc1nn(C)c2cn(C(C)C(=O)NCc3ccccn3)nc12 +CCC(C(N)=O)N1C(=O)C(C)Nc2cc(C)ccc21 +CCn1cc(C(=O)Nc2cc(C)[nH]n2)c(=O)c2ccc(C)nc21 +CNc1cc(C)nc(-c2cc(NCCO)nc3[nH]ccc23)n1 +CCc1cccc(CC)c1NC(=O)NC(C)C(=O)N1CCCCC1 +CCN(CC)C(=O)N1CCC(C(=O)Nc2cc(C)ccc2OC)CC1 +Cc1cnc(NC(=O)C2CCN(c3ncccn3)CC2)s1 +COc1ccc(CNC(=O)NCCC(O)c2ccco2)cc1 +CC(C)Oc1ccc(C(=O)Nc2cccc(O)c2)cc1 +COc1ccc(NC(=O)Cc2c(C)nc3ccccc3c2C)cn1 +Cn1nc(C(=O)N2CCCC2c2ccc(F)cc2)ccc1=O +CCc1nc(CN(C)C(=O)c2cnc(NC)s2)cs1 +CC(C)(C)c1nc(CNc2ccc(CN3CCCC3=O)cc2)cs1 +O=C(COc1cccc(-c2nnco2)c1)NC(c1ccccc1)C1CC1 +Cc1cc(C(=O)N(C)CC2COc3ccccc3O2)n[nH]1 +CC(C)(C)c1ccc(C(=O)Nc2cccc(S(C)(=O)=O)c2)cc1 +CC(C(=O)NCC(c1ccccc1)N1CCOCC1)n1cncn1 +CN(C(=O)CCC(=O)Nc1nncs1)C1CCCCCC1 +CN(c1ccc(C(=O)NCc2ccncc2)cc1)S(C)(=O)=O +Cc1cc(=O)n(CC(=O)Nc2ccc(F)cc2)c(-c2ccccc2)n1 +CCCCN(CC(N)=O)S(=O)(=O)c1ccc(F)c(Cl)c1 +CS(=O)(=O)c1ccc(C(=O)OCCCc2ccccc2)cc1 +CC1CCN(S(=O)(=O)NC(C)C(=O)N2CCCC2)CC1 +CN(C)c1ccc(NC(=O)CCCc2nc3ccccc3[nH]2)cn1 +O=C(c1cnccn1)N1CCC(C(=O)N2CCCC2)CC1 +O=C(CN1CCN(c2ccccc2F)C1=O)N1CCCCC1 +COC(=O)C1(NC(=O)c2cnn[nH]2)CCC(C)CC1 +COc1ccnc(NC(=O)c2cccc(-n3ccnc3)c2)c1 +C=CCN1C(=O)c2ccccc2NC1c1cccc(OCCOC)c1 +CC1CCCC(OC(=O)Cn2c(=O)c3c(ncn3C)n(C)c2=O)C1 +CN(C)S(=O)(=O)c1ccc(CNC(=O)CCC(F)(F)F)cc1 +Cc1cc(C(=O)NCCCc2n[nH]c(=O)[nH]2)c(C)n1C(C)C +Cc1ccc(F)cc1C(=O)N1CCN(CC(=O)N2CCCC2)CC1 +Cn1c(=O)ccn(CC(=O)NCC(O)COc2ccccc2)c1=O +COC(=O)c1cc(C(=O)Nc2ccc(C)c(C)c2)c(=O)[nH]c1C +CS(=O)(=O)N1CCCCC1C(=O)NCc1ccccn1 +O=C1CCC(COC(=O)CCc2cccc(Br)c2)N1 +CC(C)(C)c1ccc(C(=O)Cn2cnc(C#N)n2)cc1 +Nc1cc(F)ccc1NC(=O)CCCOCC(F)(F)F +CCOc1ccccc1CCn1cc(-c2ncc[nH]2)nn1 +CN(Cc1cccc(C(N)=O)c1)S(=O)(=O)c1cn[nH]c1 +COc1ccc(OCC(=O)Nc2ccc3c(c2)OCO3)cc1 +Cc1c(C(=O)N2CCN(CC(C)O)CC2)sc2ccc(F)cc12 +CC(C)C(=O)Nc1cc(C(=O)NC2CC2)nn1-c1ccccc1 +NC(=O)N1CCCC(C(=O)OCCC#Cc2ccccc2)C1 +CC(C)N(C)C(=O)c1cc(S(C)(=O)=O)c(Cl)cc1Cl +Cc1n[nH]c(C)c1S(=O)(=O)N(C)c1cccc(N)c1 +CCn1c(C(=O)NCCn2cccn2)cc2sccc21 +Cc1ccc2[nH]c(=O)c(CNc3ccccc3Cl)cc2c1 +CC1(c2ccccc2)CN(Cc2cccc3cn[nH]c23)CCO1 +CCOC(=O)c1noc2ncnc(N3CCc4ccccc4C3)c12 +CNC(=O)CN1CCOC2CN(C(=O)c3ccccn3)CC21 +CC(=O)c1c(C)[nH]c(C(=O)OCC(=O)Nc2cccc(C#N)c2)c1C +Cc1csc(C(C#N)C(=O)c2cnn(-c3ccc(F)cc3)c2C)n1 +COc1c(Br)cc(C)cc1C(=O)C1CC1 +COc1cc(CNc2ccccc2C#N)ccc1F +CN(CCOC(=O)Nc1ccccc1)c1ccc(C#N)cn1 +CCCCCNC(=O)C1CC(=O)N(c2cc(Cl)ccc2OC)C1 +Cc1ccc(Cl)cc1N1CC(C(=O)NC2CC2)CC1=O +Cc1ccc(C(=O)NC(c2cccs2)c2cccs2)cn1 +COc1cccc(NCC(=O)Nc2ccccc2C#N)c1 +C=CCOC(=O)c1ccc(-c2ccc(C)c(N)c2)o1 +O=C(Cn1cnnn1)Nc1ccccc1C(=O)NCC1CCCO1 +COc1cccc(C(=O)c2ccc(OC)c(N)c2)c1 +CCC(C)C(NC(=O)c1cnn(-c2cccc(Cl)c2)c1)C(N)=O +O=c1c2ccccc2ncn1CCCc1ccccc1 +CCCCC(=O)Nc1ccc(SCC(N)=O)cc1 +CC(C)c1nc2cc(O)ccc2n1Cc1cccnc1 +O=C(NC1CCC(O)CC1)c1ccc(-c2ccccc2)cc1 +C=CCOC1CCN(C(=O)C2CC2c2ccc(OC)cc2)CC1 +CC(=O)N1CCN(Cc2csnn2)C(C)(C)C1 +c1csc(CN2CCOC3C(OCC4CCOCC4)CCC32)n1 +CCOC1CCCN(C(C)c2nc(N)nc(Nc3ccccc3)n2)C1 +N#Cc1ccc(CNC(=O)c2cnc(C3CC3)[nH]c2=O)cc1 +CCN(C(=O)c1ccc(F)c(NC(C)=O)c1)C1CCCC1 +CN(C)C(=O)N1CCN(C(=O)Nc2ccccc2OCC2CC2)CC1 +Nc1ccc(F)c(C(=O)Nc2ccc(Br)cc2Cl)c1 +CCN(CC)S(=O)(=O)c1ccc(C(=O)N2CCCC(C)C2)cc1 +NC(=O)c1oc2ccccc2c1NC(=O)c1cc(-c2ccccc2)no1 +CS(=O)(=O)c1ccc(Cl)c(C(=O)Nc2sccc2C#N)c1 +O=C(N1CCC(Nc2cccnn2)CC1)C1(c2ccc(F)cc2)CC1 +Cc1cccc(CN2CCN(C(=O)c3cc(C(N)=O)cs3)CC2)c1 +CC(=O)NC(C)C(=O)NCc1cnc(OCC(C)C)c(Cl)c1 +CC(C#N)CN(C)c1nc(-c2cccnc2)nc2ccccc12 +COCCNC(=O)N1CC(C)CC1c1cccc(F)c1 +CC(CC(=O)NCc1cccnc1-n1cncn1)C1CCCCC1 +O=C(Cn1nc(C(F)(F)F)cc1C1CC1)N1CCc2ccccc21 +N#CCCC(C#N)Cn1c(SC(F)F)nc2ccccc21 +O=C1CC(c2cccc(Br)c2)c2cc3c(cc2N1)OCO3 +CCC1CCCN(C(=O)c2cc(F)c(F)cc2Cl)C1 +CN(Cc1ccco1)C(=O)c1cc(Cn2ccc3ccccc32)[nH]n1 +O=C(NCCCCNC(=O)c1ccccc1F)c1ccccc1F +CCc1cccc2c1OCCC2NCc1ccccc1F +C=CCSc1nc2c(c(=O)[nH]c(=O)n2C)n1CCCCC +CC(c1ccccn1)N(C)C(=O)NCC(=O)Nc1ccc(Cl)cc1 +O=S(=O)(NCC(O)C1CCCCC1)c1ccc(F)c(Cl)c1 +Cc1cc(C)n(C(C)C(=O)Nc2cc(Cl)ccc2F)n1 +Cc1nn(C(C)C(=O)Nc2nccs2)cc1Br +COCc1cccc(CNC(=O)c2nc3ccccc3c(=O)[nH]2)c1 +CCn1cc(Cl)c(C(=O)NCc2ccc3c(c2)OCO3)n1 +C=CCCCN(C)C(=O)Nc1ccc2c(c1)CCN2C(C)=O +Cc1noc(C)c1CCC(=O)Nc1ccc2c(C)cc(=O)[nH]c2c1 +Cc1nccc(N2CCC3(CCC(=O)N(CCO)C3)CC2)n1 +Cc1cc(NC(=O)NC(C)(C)c2nc(C)c(C)s2)n(C)n1 +Cc1cc(C(=O)NC(C(N)=O)c2ccccc2)c(C)n1-c1cccnc1 +O=C(Nc1nc(-c2cccnc2)cs1)c1ccccc1F +Cn1nc(C(=O)NCc2noc(-c3ccco3)n2)ccc1=O +O=C(Cn1ccc(=O)c2ccccc21)Nc1cc(F)ccc1Cl +COC(=O)C1NC(O)C2CCC1N2C(=O)OC(C)(C)C +Cc1ccccc1OCC(=O)N1CCCN(Cc2nccn2C)CC1 +CC1(C)C(=O)Nc2c(C(O)c3ccccc3)cc(F)cc21 +CC(=O)c1cnc(NCc2nnnn2-c2ccccc2)nc1C +COc1ccc(CNC(=O)Cn2nc(-c3ccco3)ccc2=O)cc1 +CCCNC(=O)CNC(=O)Nc1cc(NC(=O)C2CC2)ccc1C +Cc1cn2cc(NC(=O)c3occc3C)ccc2n1 +CCC(C)C(NC(=O)Nc1ccccc1C)C(=O)OC +CCC(C)N(C(=O)c1cccc(OC)c1)C(C)CC +Cc1cc(NCc2ccccn2)ccc1Br +Cc1ccc(C2CSc3nnc(C4CC4)n3N2)cc1 +CC(NC(=O)Cn1nc(C(F)(F)F)c2c1CCC2)c1ccccc1 +Cc1cc(C(=O)NCc2ccnc(OC3CCC3)c2)[nH]c(=O)n1 +CCOc1ccc(CNC(=O)c2cc(C(N)=O)cs2)cc1OC +COC(=O)c1ccc(Cl)c(NC(=O)NCC(C)C)c1 +CC(NC(=O)Nc1ccc(C(N)=O)cc1)c1nc2ccccc2[nH]1 +Cn1c(=NC(=O)C2CCCO2)[nH]c2cc(Cl)ccc21 +CN(CCCCNC(=O)Nc1cccc(C#N)c1)c1ccccc1 +Cc1ccc(Cl)cc1-n1nnc(CO)c1C1CC1 +COc1cc(SC)ccc1C(=O)N1CCN(c2ccccn2)CC1 +CCOC(=O)C1CC(=O)N(c2cc(C)ccc2OC)C1 +CC(C)N(CCCO)C(=O)Cc1cn2ccsc2n1 +CC(C)c1ncc(Cl)c(C(=O)N2CCOCC2C2CC2)n1 +CCc1ccc(C(=O)CSc2nnc(C)o2)cc1 +Cc1nc(CN(C)C(=O)c2cc(Cl)ccn2)cs1 +CCc1onc(C)c1NC(=O)NCCNC(=O)c1ccco1 +CC1CCCC1NC(=O)C(Cc1c[nH]c2ccccc12)NC(N)=O +CC1(C(=O)N2CCC(C(N)=O)c3ccccc32)CCCO1 +COC(=O)c1c(NC(=O)Cc2ccc(OC)cc2)c(C)nn1C +CCNC(=O)NC1CN(C(=O)Cc2ccccc2O)CC1OC +Cc1cccc2nc(C(=O)N(C)Cc3ccccc3N3CCCC3)cn12 +Cc1nc2cc(-c3cc(Cl)c(C#N)cn3)ccc2o1 +Cn1nc(C(C)(C)C)cc1C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +O=C(Nc1nc(-c2cccc3ccccc23)cs1)c1cccnc1 +O=C(c1ccccn1)N(Cc1ccco1)CC1CCCO1 +Cc1ccc(C(=O)OCC2CC(=O)N(C3CC3)C2)c(C)c1 +CCOC(=O)N1CCC(C#N)(NS(C)(=O)=O)CC1 +CNC(=O)c1cccc(OCc2nc(-c3ccc(C)cc3F)no2)c1 +Cc1ccccc1COC1CCN(C(=O)C(C)n2cccc2)CC1 +CC(C)N(C(=O)CNc1ccc(-n2cccn2)cc1)c1ccccc1 +NC(=O)Cc1ccc(NC(=O)c2ccccc2F)cc1 +CCCC(=O)N1CCC(n2c(C3CCC3)nc3cccnc32)CC1 +CSc1cc2c(cc1NC(=O)N(C)Cc1ccco1)OCCO2 +Cc1nnc(Cc2ccccc2N)n1C1CCCC1 +CCOc1ccccc1NC(=O)Nc1ccncc1 +COc1ccc(CN(C)C(=O)c2ccc(=O)n(C)c2)cc1F +Cc1c(C(=O)NCc2ccc(OC(C)C)nc2)cnn1C +Nc1ccc2c(c1)N(C(=O)Cc1ccsc1)CCS2 +CC(=O)Nc1ccc(-c2cn(Cc3snnc3C(C)C)nn2)cc1 +CN(C)c1ncnc(Nc2cccc3ccccc23)c1N +O=C(NCc1cc(F)ccc1F)NC1CCCCC1 +CCCCCc1nnc(NC(=O)NCc2cccc(C#N)c2)s1 +COC(=O)Nc1cccc(NC(=O)CCC(=O)c2ccc(C)s2)c1 +NC(=O)C1CCCN1C(=O)c1c(-n2cccc2)sc2c1CCC2 +CCc1ccc(Cl)c(CC)c1NC(=O)N(C)Cc1cc(C)on1 +Cn1nc(C(=O)NCCc2ccc(F)cc2)c2ccccc2c1=O +CC(C)c1nnc(CNC(=O)Cc2ccccc2F)s1 +COc1ccc(NC(=O)c2cccc(C)c2OC)cc1N +Cc1cccc(C)c1NC(=O)c1ccc(S(C)(=O)=O)cc1 +COCc1ccccc1C(=O)NCCNC(C)=O +Cc1cc(C)c2[nH]c3nc(SCCN4CCOCC4)nnc3c2c1 +COc1ccccc1NC(=O)CSc1nc(N)cc(N)n1 +Cc1cc(C)cc(C(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)c1 +CCCSc1n[nH]c(=O)nc1NCc1ccc(F)cc1 +Cc1nc[nH]c1-c1nccn1-c1cccc(N2CCNC2=O)c1 +NC(=O)C1CCCCN1C(=O)CCn1ccccc1=O +CCCOc1ccc(CNC(=O)c2cccnc2)cc1OC +N#CCCN(c1nnnn1-c1ccccc1)C1CC1 +CC(NC(=O)c1cccc(-n2cnnc2)c1)c1ccc2c(c1)CCC2 +Cc1nc(CNC(=O)NCc2c(F)c(F)cc(F)c2F)c(C)s1 +COc1cc2c(cc1OC)C(c1ccnn1C)N(C(C)=O)CC2 +CCOC(=O)c1c(C)n(C)c2cc(F)c(O)cc12 +CCN(Cc1ccccc1)C(=O)CNC(=O)NCc1nc(C)c(C)o1 +O=C(Cn1cnccc1=O)NCCCn1ncccc1=O +COc1ccc(C(C)COC(=O)c2ccc(C(N)=O)nc2)cc1 +Cc1cc(NC(=O)c2ccccc2C#N)c2ncccc2c1 +N#Cc1nncn1CC(=O)Nc1ccccc1Sc1ccccc1 +COCCCn1c(SCc2c(Cl)cccc2Cl)n[nH]c1=O +O=C1COc2ccc(C(=O)COC(=O)c3ccccc3F)cc2N1 +COCCCNC(=O)C(N)c1ccc(F)cc1F +COc1ccc(Cl)cc1Nc1ncnc(-n2ccnc2)c1N +CCc1nc2ccccc2n1CC(O)c1ccccc1F +CC(=O)c1ccccc1OCc1ccc(S(=O)(=O)N(C)C)o1 +CC(Nc1ccc(N)cc1C(N)=O)c1cccs1 +CC(c1ccccc1)N(C)C(=O)Cn1cc(Br)ccc1=O +COC(=O)c1n[nH]c2ccc(NC(=O)c3cccs3)cc12 +CC(Cc1ccsc1)NC(=O)c1coc(CN2CCOCC2)c1 +O=C(C(c1ccccc1)n1cnnn1)N1CCC2(O)CCCCC2C1 +CCC(C)NC(=O)C1(C)CCC(=O)N1Cc1ccccc1OC +Fc1cccc(Cn2nccc2-c2ccncc2)c1 +CC(C#N)CNC(C)c1ccccc1C(F)(F)F +CC(C)C(NC(=O)C1CCCN(S(=O)(=O)N(C)C)C1)C(C)C +Cc1cc(C2CCCCN2C(=O)COc2ccc(F)cc2F)no1 +CCc1cccc2c(C(=O)COC(=O)c3cc(C)oc3C)c[nH]c12 +Cc1cc(C)c(S(=O)(=O)NCC(C)n2cncn2)c(C)c1 +c1ccc(CN2CCOC(c3cccnc3)C2)cc1 +Cc1c(C(=O)NCc2cn[nH]c2)oc2ccc(Br)cc12 +O=C(Nc1cccc(OCCc2ccccc2)c1)c1cnccn1 +COCCCNC(=O)CS(=O)(=O)c1nccn1C +Cc1cccc(Nc2nc(C(=O)NCCCn3ccnc3)cs2)c1 +Cc1c(NC(=O)Cc2c[nH]c3c(C)cccc23)cccc1C(N)=O +C=CCc1ccc(OC(=O)Cn2c(=O)[nH]c3ccccc32)c(OC)c1 +Cc1nc2ccc(NC(=O)N3CCC(n4cccc4)CC3)cc2o1 +N#Cc1cnc(NC(=O)Nc2ccc(Cl)c(Cl)c2)s1 +Cc1cc(CN(C)C(=O)c2cc3cc(F)ccc3[nH]2)no1 +CN(Cc1ccccn1)c1ccnc2c(F)cc(Br)cc12 +N#Cc1ccccc1COc1ccc(C(=O)NC2CC2)cc1 +COc1cc(-c2nc3cc(C)cnc3o2)cc(OC)c1OC +COCC(O)CN(C)C(=O)c1ccc(-c2nc(C)cs2)cc1 +O=C(NCCc1cc(F)ccc1F)NCC1CC(=O)N(C2CC2)C1 +COC(=O)N1CCC(CNC(=O)Nc2c(F)cccc2F)CC1 +Cc1cccc(CS(=O)(=O)NCC#Cc2ccc(C(N)=O)cc2)c1 +CC(=O)NC(C)C(=O)NC(C)c1ccc(C(F)(F)F)cc1 +O=C(Nc1ncccc1OC(F)F)c1cccc(F)c1 +O=C(Nc1ccc(N2CCCC2)nc1)c1cc(Cl)ccc1F +O=C(Cn1cnc2ccccc21)Nc1nc(-c2ccco2)cs1 +Cc1cc(C)cc(C2CCN(C(=O)c3ccncc3)C2)c1 +COc1cc(-c2nc(-c3ccc(C#N)cn3)no2)cc(OC)c1OC +CCNc1ncc(C(=O)N(C)Cc2nc(-c3cccnc3)no2)cn1 +CC(=O)c1ccc(N2CCN(C(=O)Cc3ccc[nH]3)CC2)c(F)c1 +CNC(=O)c1ccc(Cl)c(NC(=O)CCCc2cccs2)c1 +CC(NC(=O)C(C)(C)C)C(=O)Nc1ccc(N2CCCCC2)nc1 +CN(CC1CCCO1)C(=O)c1cccc(F)c1F +O=C(NCCc1cccc(Cl)c1)NCC1CCC1 +CC(C)c1cc(C(=O)Nc2ccc3c(c2)OCCO3)on1 +CCNC(=O)CN1CCN(C(=O)Nc2ccc(OC)cc2)CC1 +COC(=O)Cc1nnn(CC(=O)NCc2ccccc2F)n1 +COc1ccc(C(=O)N2CCC3CCCCC32)nn1 +O=C(CCn1cnc2sccc2c1=O)N1CCOC2CCCC21 +COc1ccc(OC)c(C(=O)CSc2nc3cccnc3n2C)c1 +CC(=O)N1CCN(c2nc(=O)c(C(C)(C)C)n[nH]2)CC1 +CCN(CCC#N)C(=O)CSc1nncs1 +Cc1cc(NC(=O)N(C)CC2(CO)CCOCC2)n(C)n1 +COC1CCC(OC(=O)c2cccc(OCC(F)F)n2)CC1 +CN(C)S(=O)(=O)CCNC(=O)c1ccc(C2CCCO2)s1 +O=C(Nc1cc[nH]n1)C1(c2cccc(Cl)c2)CCC1 +CCc1cc2c(Oc3cccc(C(=O)NC)c3)ncnc2s1 +CCc1nnc(SCC(=O)Nc2ccc(C(C)CC)cc2)n1N +O=C(Nc1ccccc1)C(c1ccccc1)N1Cc2ccccc2C1=O +COc1ccc(F)c(NC(=O)c2ccc(-c3ccco3)nc2C)c1 +CCc1cc(=O)[nH]c(SCC(=O)NCCOC)n1 +Cc1ccc2c(c1)CCCN2C(=O)CCc1c(C)noc1C +Cc1csc(CNS(=O)(=O)c2ccc3ccccc3c2)n1 +O=C(CCCn1sc2ccccc2c1=O)Nc1ccccc1O +CCc1ncnc(N2CCOCC2c2c(C)n[nH]c2C)c1F +Cc1csc2oc(C(=O)c3ccccc3)c(N)c12 +CN(C)c1ccccc1-c1cccc2nc(N)nn12 +CCOC(=O)c1cc(NC(=O)c2ccc(-n3cccc3)nc2)c[nH]1 +CN(C)C(=O)N1CCC(C(=O)NCCNc2ncccn2)CC1 +O=C(c1ccco1)N1CCn2c(nnc2C(F)(F)F)C1 +Cc1noc(C)c1CNc1ccccc1C(=O)N(C)C +Cc1cc2c(cc1N)CN(C1CCCC1)S(=O)(=O)C2 +COc1ccccc1C(C)(C)NCC(=O)NCC1CCC1 +COCCCNC(=O)COc1ccc(Br)cc1F +COCC(NC(=O)c1cc(F)ccc1Br)C(N)=O +CC(=O)N1CCc2nc(C3CCN(C(=O)C4CCC4)CC3)ncc2C1 +CC(O)CC(C)(C)CNC(=O)c1c(F)cccc1Br +CCn1nc(C(=O)NC2CCCC2)c(=O)c2ccccc21 +O=C(C1CC1)N1CCC(n2cnc3cc(F)ccc32)CC1 +CC(C)(C)NC(=O)CCCc1nc2ccccc2c(=O)[nH]1 +CC1CN(C(=O)c2cccc(OCc3cscn3)c2)C(C)CO1 +O=C(Cc1c[nH]c2ccccc12)N1CCN(C(=O)c2ccccc2)CC1 +O=C(COc1ccc(F)cc1)NCCc1cccs1 +Cc1oc(C(=O)NCC(C)c2ccsc2)cc1S(N)(=O)=O +COc1cc(N)cc2sc(NC(=O)C(C)(C)C)nc12 +COc1ccc(Cl)cc1NC(=O)Cc1noc(-c2ccco2)n1 +CCC(NC(=O)c1ccc2c(c1)OCO2)c1ccc(Cl)cc1 +CNC(=O)c1cccc(NCc2ccc(F)cc2F)c1C +CC(C)(C(=O)N1CCN(C(=O)c2ccccc2)CC1)c1ccccc1 +O=C(NCc1ccco1)C1CC2OCCC2N(c2ncc(F)cn2)C1 +CCC(COC(=O)C1CCN(C(C)=O)CC1)c1ccccc1 +Cc1ccc(C)c(S(=O)(=O)N(C)Cc2c(Cl)cnn2C)c1 +CC(=O)NCCNC(=O)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +O=C(NCCC1CN(C2CCCC2)CCO1)c1c[nH]c(=O)[nH]c1=O +Cc1n[nH]c2c(NCCCn3cccn3)ncnc12 +Cc1c(C#N)c(=O)oc2c(Cl)cc(Br)cc12 +Cc1occc1C(=O)N1CCCN(S(=O)(=O)c2ccccc2)CC1 +COC(C)(C)c1noc(-c2ccc(=O)n(C)n2)n1 +CCOC(=O)Cn1c(C(C)NC(=O)CC)nc2ccccc21 +COc1ccc2c(c1)OCC(C(=O)N(C)CC(O)C1CC1)C2 +Cc1n[nH]cc1CNS(=O)(=O)N1CCCC(C)C1 +CN(C)C(=O)COc1ccc(NC(=O)C2CCC2)cc1 +CN1C(=O)CC2C1CCN2C(=O)CCc1ccccc1 +CCc1cc(NCc2ccon2)n2nc(C)c(C)c2n1 +CC(C)CC(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +CCn1cc(C(=O)NCCCO)c(=O)c2ccccc21 +O=C(CNC(=O)c1ccc(Cl)c(Cl)c1)OC1CCCCC1=O +CC(CNC(=O)c1ccc2[nH]cnc2c1)N1CCOCC1 +CC(=O)Nc1cc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)ccc1Cl +CCn1cc(NC(=O)C2CCN(C(=O)CC3CCCO3)CC2)cn1 +Cc1ccc(SCC(F)(F)F)c(NCC(=O)N2CCOCC2)c1 +CCCN(CC(F)(F)F)c1c(CO)c(C)nn1C +Cc1cccc(C(C(=O)NCc2noc(-c3ccco3)n2)N(C)C)c1 +O=C(Nc1nncs1)C1CCCN(c2ncnc3[nH]ccc23)C1 +O=C1CCCc2cc(OCc3nnnn3-c3ccccc3)ccc21 +CC(C)(C)Oc1cc(CNC(=O)C2CC2(Cl)Cl)ccn1 +CCC(CC)CC(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +CNC(=O)Cn1nc(C#N)cc1-c1ccc(Cl)c(C)c1 +NC(=O)c1ccc(NC(=O)c2ccc(F)nc2)cc1 +COc1ccc(NC(=O)C2CCN(C(C)=O)CC2)cc1 +CN1CC2(CCN(C(=O)OC(C)(C)C)CC2)Nc2ccccc21 +CCCN(CCC)C(=O)c1csc(NC(=O)c2cccc(F)c2)n1 +COC(=O)c1ccc(C(=O)N2CCCCCC2c2ccco2)nc1 +COc1cc2c(cc1O)CCNC2C=Cc1ccco1 +CCN(CC(F)(F)F)C(=O)c1cnc(-c2cccnc2)nc1 +COc1ccc2nc(C(=O)NCC(C)(C)C)sc2c1 +COc1ccc(C(=O)N2CC3CC=CCC3C2)nn1 +CC(=O)NCc1cccnc1Oc1ccc(C)nc1 +O=C(CCn1ccccc1=O)N1CCCCC1c1cccc(F)c1 +Cc1cc(C(C)NC(=O)c2cc(Cl)c[nH]2)c(C)o1 +CCNC(=O)c1ccc(OCc2c(C)noc2C)c(OC)c1 +O=C(NCc1ccncc1)NCc1cccc(C(F)(F)F)c1 +CCOC(=O)c1c(NCc2ccccc2)c2ccccc2n(C)c1=O +CCOC(=O)CCSc1nc2ccccc2c(=O)n1C +CN(CCCOc1ccccc1)C(=O)Nc1cccc2c1OCCO2 +CC(=O)c1c(C)cc(C)c(CN2CCN(c3ncccn3)CC2)c1C +C=CCCCN(C)C(=O)c1cc(C)cc(OC)c1O +COc1cc(NCc2cccnc2)nc(C2CCCCC2)n1 +CC(C)CNC(=O)NCc1ccc(-n2cccn2)cc1 +COc1ccc(N)cc1NC(=O)C(C)Oc1cccc(C)c1 +O=C(O)C1CN(c2cc(Cl)ccc2Cl)C1=O +COCCNC(=O)c1nn(-c2ccccc2C)c(=O)cc1OC +Cc1ocnc1CNC(=O)Nc1ccc(OC2CCCC2)cc1 +COC(=O)c1cc(-c2ccc(OC(F)F)cc2)nc2c(C#N)cnn12 +CC1CN(C(=O)C(NC(=O)c2ccco2)C(C)C)c2ccccc21 +CCNC(=O)N1CCC(S(=O)(=O)c2ccccc2)CC1 +Cc1noc(C)c1CCCNS(=O)(=O)Cc1cccc(C#N)c1 +CCC(O)(CC)CNC(=O)Nc1ccc(Oc2cccnc2)nc1 +Cc1ccc(-c2noc(CCC(=O)Nc3cccnc3)n2)cc1 +CN(CC(=O)Nc1ccccc1N)c1ccccc1 +COc1ccc(C(=O)N(C)C2CCCCCC2)cn1 +Cc1oncc1C(=O)N1CCC(C(=O)NCC2CCCC(C)C2)CC1 +N#CCCn1c(-c2cccnc2)nc2cc3c(cc21)OCO3 +CC(NC(=O)NCCO)c1ccc(OCc2cccnc2)cc1 +O=C(NCc1cccc(F)c1)c1ccc(Oc2nccs2)cc1 +Cc1noc(C(C)C)c1C(=O)N1CCC(c2nnc3n2CCC3)CC1 +CCCS(=O)(=O)NCC(C)c1nc(-c2ccccc2)no1 +Fc1cnc(N2CCC3(CC2)COC(COc2ccccn2)C3)nc1 +C=CCn1c(CSc2ccc(C)cc2)nnc1SCC#N +O=C(NCC1CN2CCCCC2CO1)NC1CCCc2occc21 +CNC(=O)C(C)Sc1nnc(-c2ccccc2Br)o1 +Cc1cc(C)n(CC(=O)N(C)C(C)CC(C)C)n1 +CCc1ccc(Cc2nnc(NC(=O)c3cc(C)n(C)n3)o2)cc1 +COc1ccc(NC(=O)c2cc(C3CC3)nc3ccccc23)cn1 +NC(=O)C1CCN(C(=O)CC2CSc3nccc(=O)n32)CC1 +OC1CCC(Nc2ncnc3scc(-c4ccc(F)cc4)c23)CC1 +O=C(CCCCO)Nc1cc(C(F)(F)F)ccc1Cl +CC(C)Nc1nnc(SCc2nnc(C(C)(C)C)o2)s1 +CSc1nsc(NC(=O)C(C)NC(=O)c2cccc(C)c2)n1 +COc1cccc(NC2CCN(S(=O)(=O)CC(C)C)CC2)c1 +O=C(Nc1ncn(Cc2ccccc2)n1)NC1CC1 +O=C(CCn1cc(Cl)cn1)NCc1ccc2c(c1)OCO2 +CCC(=O)N(Cc1cccnc1)c1nc2c(C)cc(Cl)cc2s1 +CCc1nc(CN2CCN(C(=O)c3ccco3)CC2)cs1 +CC(Oc1ccccc1C#N)C(=O)NCC1CN2CCCCC2CO1 +CC(C)C(Sc1nnnn1C1CC1)C(=O)NCc1ccccc1F +Cc1ccccc1CS(=O)(=O)c1ccc(C(=O)N2CCCC2)cn1 +N#Cc1ccc(CNc2cc(Cl)ccc2O)cc1 +Cc1[nH]nc(O)c1CC(=O)NCc1cc(-c2ccccc2Cl)on1 +COc1ccc(OC)c(CCCNc2ncnc3oncc23)c1 +COCc1cc(NC(c2nc3ccc(C)cc3[nH]2)C(C)C)ncn1 +O=C1CN(C(=O)c2ccc3noc(-c4ccccc4)c3c2)CCN1 +CC(Sc1ncnc2sc3c(c12)CCC3)C(=O)N1CCCCC1 +Cc1cccc(NC(=O)CCN(C)c2ccc(N)cn2)c1C +O=C(CC1CCCC1)N1CCC(Oc2cc(N3CCCC3)ncn2)C1 +O=C(CCc1ncc(-c2ccccc2F)o1)NCC1CCOC1 +CC(C(=O)OC1(C)CCC1)N1CCc2ccccc2C1 +CC(NC(=O)c1ccc(Cn2cccn2)cc1)c1nnc2ccccn12 +O=C(NCc1ccccc1Cl)c1cn[nH]c1-c1cccs1 +CCOc1ccc2cc(C(=O)Nc3ccc(Cl)cn3)c(=O)oc2c1 +COc1c(C)cc(S(=O)(=O)N(C)CCO)c(C)c1C +CCOc1cc(C(=O)N2CCc3sccc3C2CC)ccc1OC +CCS(=O)(=O)NCCc1csc(-n2nc(C)cc2C)n1 +O=C(NCC(NC(=O)C1CCC1)C1CCCCC1)C1CCC1 +CC1CCCN(C(=O)CCNC(=O)c2ccc(F)cc2F)C1 +CCOC(=O)CNC(=O)c1scnc1C1CC1 +Cc1cc(C)c(NC(=O)c2ccccc2F)c(C)c1 +CC(c1cccnc1)N(C)C(=O)Nc1cnn(Cc2ccccn2)c1 +Cc1nccc(CNC(=O)CCSc2ccccc2)n1 +CNc1cc(C(=O)N2CCC(Cc3ccc(F)cc3)CC2)ccn1 +Cc1ccc(NC(=O)C(C)Sc2ccccn2)cc1C(N)=O +CCOc1ccc(C(=O)c2cccc(N)c2)c(C)c1 +COC(=O)C(CC(C)C)NC(=O)c1ccc(NC(N)=O)cc1 +O=C(c1ccoc1)N1CCC2(CC1)COC(COc1cccnc1)C2 +CC(=O)NC(C(=O)Nc1ccc(-n2cccn2)nc1)C1CCCC1 +CCCCNS(=O)(=O)c1ccc2c(c1)CCN2C(C)=O +CCn1c(=O)c2c(ncn2CC)n(-c2cccc(F)c2)c1=O +Cc1ccc(CC(=O)NCc2ccc(NC(=O)c3ccco3)cc2)cc1 +COC(=O)c1cc(CNC(=O)Cn2c(=O)[nH]c3ccccc32)oc1C +O=C1CN(C(=O)c2cc3c(s2)CCCC3)CCN1 +CNC(=O)Cn1nc(C#N)cc1-c1ccc(OC)cc1C +OC(c1ccccc1F)C1NCCc2ccccc21 +COc1cc(C)c(C)cc1S(=O)(=O)Nc1ccc2c(c1)CC(=O)N2 +Cc1cc(F)ccc1NC(=O)NCCC(=O)OC(C)C +CC(=O)Nc1ccccc1NC(=O)c1ccc(C)c(Cl)c1 +CCCOc1cc(C)c(S(=O)(=O)Nc2cccnc2)cc1C +COc1cccc(OCC(=O)N2CCN(CCn3cccn3)CC2)c1 +O=C(Nc1cccc(N2CCCC2)c1)NC1CC=CC1 +NC(=O)OCCNC(=O)c1cc(F)cc(C(F)(F)F)c1 +CC(=O)c1ccccc1NC(=O)Cn1nc2ccccn2c1=O +Nc1ccccc1OCCCCn1nnc2cc3c(cc21)OCO3 +COC(=O)C(C)Sc1ncnc2c1oc1ccccc12 +CC(=O)C(NC(=O)CSc1nnc(C)o1)C(C)C +CCCNC(=O)Nc1cnn(-c2cccc(C(F)(F)F)c2)c1 +CCOc1ccc(CCC(=O)N2CCN(C3CCCC3O)CC2)cc1 +CCCn1cc(NC(=O)c2cnc3ccc(C)cn23)cn1 +CCc1nc2nnc(-c3ccnc(N4CCCC(C)C4)n3)c(C)n2n1 +O=C(NCCC(=O)N1CCc2nocc2C1)c1cccs1 +Nc1nc(-c2ccccn2)c(Br)c(=O)[nH]1 +O=C(Cc1cccc(F)c1)N1CCN(C(=O)c2cccc(O)c2)CC1 +Cc1occc1CN(C)CC(=O)c1c(N)n(C2CC2)c(=O)[nH]c1=O +Cc1nonc1NC(=O)c1cccc(-c2ccoc2)c1 +CSc1ccc2nc(NC(=O)c3ccn(C)n3)sc2c1 +Cc1ccc2nc(SCCCc3cnn(C)c3)n(C)c(=O)c2c1 +COc1cccc(C(=O)Oc2cccc3[nH]ncc23)c1 +Cc1nn(C)c(C)c1NC(=O)c1cc2ccccc2c(=O)[nH]1 +Cc1oc(CO)cc1C(=O)OCC(=O)Nc1ccc(C#N)cc1 +CCc1nc(CNc2cccc(CN(C)C(C)=O)c2)cs1 +O=C(c1cccc(CN2CCOCC2)c1)N1CCc2ccccc21 +Cc1nnc(COc2ccc(N)cc2Cl)n1C +COc1ccc(-n2c(Cn3ccnc3)n[nH]c2=O)c(C)c1 +CC(C)Nc1cccc(CNC(=O)NCC(C)(C)C(N)=O)c1 +CC(Oc1ccc(C(N)=O)cc1)C(=O)Nc1ccccc1C#N +O=C1CC(C(=O)N2CCOCC2C2CC2)CN1c1ccccc1Cl +COc1ccc(-n2nc(C(N)=O)c(=NC(=O)c3ccco3)s2)cc1 +CCC(=O)c1ccc(OCC(O)CN2CCc3ccccc32)cc1 +COC(=O)c1ccc(CN2c3ccccc3C(C(N)=O)CC2C)cc1 +Cc1ccsc1-c1nnc(SCc2nnc(C3CC3)n2C)o1 +CN(Cc1ccccc1F)C(=O)c1cccc(O)c1 +CC(=O)N1CCN(Cc2ccc(C3=NC(=O)C(C)C(C)=N3)cc2)CC1 +N#Cc1c[nH]c(-c2ccc(OC3CCCC3)cc2)cc1=O +CN1C(=O)C(O)(CC(=O)c2ccco2)c2ccccc21 +CCOc1ccc(CNC(=O)c2cnn(CC)c2)cc1F +CN(CCC(F)(F)F)S(=O)(=O)c1cn(C)c(=O)n(C)c1=O +Cc1ccc(C(=O)N(Cc2ccoc2)Cc2cccs2)cc1C +CCCCN(CCCC)C(=O)C1CC(=O)OC12CCCCC2 +O=C(COc1ccccc1Cl)Nc1ccc2c(c1)COC2 +CCNC(=O)Cc1csc(Nc2ccc(S(C)(=O)=O)cc2)n1 +CCc1onc(C)c1NC(=O)NC1(c2ccccc2F)CC1 +COc1ccc(C(=O)CN2C(=O)c3ccccc3S2(=O)=O)cc1 +CCc1c(C(=O)NC2CCCC2)[nH]c(C)c1C(C)=O +CCOCc1ccccc1CNC(=O)N(C)Cc1cc(C)on1 +CCCOc1ccc(C(F)(F)F)cc1NC(=O)c1cnccn1 +O=C(NCCc1ccccc1)Nc1cnn(C2CCOC2)c1 +CCN1CCN(C(=O)c2ccc(-c3ccccc3)[nH]c2=O)CC1 +Cc1ccsc1C(O)CNC(=O)Nc1ccccc1C(F)(F)F +CC(C)n1cc(C(=O)N(C)CC2Cc3ccccc3CN2C)cn1 +CC(Nc1ccc2nnnn2n1)c1ccc2c(c1)CCCC2 +Cc1ccsc1CNc1cnn(CC(F)(F)F)c1 +COC(=O)N1CCC(Nc2ncnc3c2CCCC3)CC1 +CCOCCNC(=O)N1CCN(CC(=O)NC2CC2)CC1 +CC(C)N1CC(C(=O)N(C)Cc2noc3c2CCCC3)CC1=O +CCn1cc(NS(=O)(=O)c2cccc(N)c2)cn1 +CC(C)(C)CNC(=O)c1[nH]cnc1C(=O)N1CCc2ccccc2C1 +Cc1nn(C)c(C)c1C(C)NC(=O)Nc1cccnc1 +Cc1ccccc1-c1ccc(CC2CCCN(S(C)(=O)=O)C2)nn1 +CCc1cc2c(=O)[nH]c(Cc3ccc(C(=O)OC)o3)nc2s1 +COc1ccc(C(=O)NCC2CC(=O)N(c3ccc(F)cc3)C2)cc1 +Cc1cnn(CCC(=O)N2CCN(C(=O)OC(C)(C)C)CC2)c1 +CC(C)OCCn1nc(C2CC2)cc(C(F)(F)F)c1=O +CCc1nnc2n1CCN(C(=O)c1cnc3ccccc3n1)C2 +COc1ccc(CC(=O)NCCCO)cc1C(C)(C)C +CC(NCC(O)c1ccco1)c1nc2cc(Cl)ccc2n1C +CCOC(=O)C1CCN(C(=O)c2nnc3ccc(C)cc3n2)CC1 +CCc1cccc(NC(=O)Cn2c(C(=O)OC)cc3occc32)c1 +COc1ccc(F)cc1NC(=O)N1CCCC(OC)C1 +Cc1ccsc1CNC(=O)C1COc2ccccc2O1 +Cc1ccccc1C(C)NC(=O)NCCOCC(F)(F)F +Cc1cccc(OCCC(=O)N2CCC(O)CC2)c1 +Cc1cccc(-c2ccc(C(=O)NCc3ccc(C)o3)cn2)c1 +COCCn1c(SCc2nc(C)c(C)o2)nnc1-c1ccncc1 +CC(O)C(=O)Nc1ccc(Cl)cc1C(F)(F)F +O=C(NCCc1nnc2ccccn12)c1cc2c(s1)CCCCC2 +Cc1c(NC(=O)c2ccco2)cccc1NC(=O)c1ccco1 +CCCNC(=O)CN(C)C(=O)CNc1c(F)cc(F)cc1F +CN(c1ccc(NC(=O)C2COCCO2)cc1F)C1CCCCC1 +CCCOc1cccc2c1CCNC2c1ccco1 +OC(Cc1nc2ccccc2s1)C(Cl)(Cl)Cl +Cn1c(C(=O)Nc2ccn(Cc3ccccc3)n2)cc2occc21 +CCOc1ccc(F)c(C(=O)N(C)Cc2ccc(C)o2)c1F +CCOc1ccc(CNS(C)(=O)=O)cc1OC +CC(Sc1nc2ccccc2o1)C(=O)Nc1ncccn1 +CCCn1nc(C)c2c(C(=O)Nc3ccc(OC)cc3)cc(C)nc21 +O=C(Nc1ccc(S(=O)(=O)NC2CC2)cc1)c1ccoc1 +Cc1cc(Cn2nnc(-c3ccc(C(C)C)cc3)n2)no1 +COc1cccc(NC(=O)C2CCN(C(=O)C3CC3)CC2)c1 +Cc1cc(F)c2[nH]c(=O)cc(C(=O)N(C)Cc3nccs3)c2c1 +COc1ccc(C(=O)c2cnc3ccccc3c2)cc1 +Cc1csc(NC(=O)c2cccc(NC(=O)c3ccccc3)c2)n1 +CC1CCCN(C(=O)C2CC(=O)Nc3cc(F)ccc32)C1 +CC(C)c1nccn1Cc1cccc(NC(=O)NC2CC2)c1 +COCCNC(=O)c1ccccc1Sc1ccccc1C#N +CC(C)=CC1C(C(=O)N2CCCN(c3cccnn3)CC2)C1(C)C +Cc1nc(C(=O)Nc2ccc(-c3cn4ccsc4n3)cc2)cs1 +O=S1(=O)CCCN1CCCOc1ccc2ncccc2c1 +COC(=O)C(C)n1c(=O)[nH]c2cc(OC)ccc21 +COc1ccc(-c2cc(-c3ccc(F)cc3)nc(N)n2)cc1OC +CC1CCCC(NC(=O)CNc2ccc(C#N)cc2)C1 +Cc1nnnn1-c1cc(N)ccc1C(=O)OC(C)C(=O)NCC(C)C +CC(=O)NC(CC(=O)N1CCCC1)c1ccc(C)cc1 +Cc1cn2nc(N3CCCC3c3cc(C)on3)sc2n1 +Fc1ccc(F)c(Cn2cccc2-c2nc(-c3ccncc3)no2)c1 +Cc1ccc(C(=O)Nc2ccccc2C(=O)Nc2cccnc2)cc1 +Cc1noc(C)c1Cn1ccnc1-c1ccncc1 +CNC(=O)c1ccc(NC(=O)CNC(=O)c2ccc(C)c(C)c2)cc1 +O=C(CCNC(=O)c1ccc(F)cc1F)NCc1csc(=O)[nH]1 +O=C(CN1CCCCC1=O)NC1CCc2cc(Cl)ccc21 +Cn1cccc1CNc1ccc(F)cc1OCC(F)(F)F +Cc1nn(C)cc1CN1CCCN(c2nc3ccccc3s2)CC1 +Cc1cnn(C)c1C(=O)Nc1nc2c(C)cc(Cl)cc2s1 +CCn1nc(C)c(S(=O)(=O)NCc2ccc(C)c(OC)c2)c1C +CC(C)N(C(=O)CSc1nc2n(n1)CCCCC2)c1ccccc1 +CC1CC(=O)c2cnc(NC(=O)Nc3ccc(Cl)cc3)nc2C1 +Cc1cc2c(=O)n(CC(=O)NC3CCCCC3C)cnc2s1 +CCCc1nn2c(C#N)c(-c3ccccc3OC)nc2s1 +COC(=O)CCCN(C)C(=O)c1cccc(C)c1O +CSc1ccc(C)c(C(=O)N2CCCC(C(N)=O)C2)c1 +Cc1cccc(OCCNC(=O)N2CCC(C(N)=O)CC2)c1 +Cc1cccc(-c2noc(Cn3cnc4c(cnn4C)c3=O)n2)c1 +CCCC1CCC(NC(=O)c2nonc2N)CC1 +CCc1cccc(NC(=O)C(C)NS(=O)(=O)c2cccs2)c1 +Cc1ccc(NC(=O)N2CCN(Cc3nc(C)no3)CC2)cc1 +CC(=O)Nc1cccc(C(=O)NC2(Cc3ccc(C)cc3)CC2)c1 +c1csc(-c2nnc(COc3ncnc4ccccc34)o2)c1 +COc1ccc(N2Cc3ccccc3C2=O)cc1OC +CN(Cc1cccnc1)c1ccc2scnc2c1N +COC(=O)c1cnc2ccc(Br)cn12 +CCC(C)N(C)C(=O)CCS(=O)(=O)c1ccc(Cl)cc1 +CC(NC(=O)COCc1nc2ccccc2c(=O)[nH]1)C1CCCO1 +CC(=O)c1ccccc1NC(=O)COc1ccccn1 +COc1ccc(CC(=O)N2CCC(O)(C(F)(F)F)CC2)cc1OC +O=C1COc2ccc(C(=O)NCCCOC3CCCCC3)cc2N1 +CC(=O)Nc1cccc(OCCNC(=O)Nc2nnc(C)s2)c1 +CC(=O)Nc1ccc(S(=O)(=O)N(C)CC(C)C)cc1 +CC(=O)N1CCC2(CC1)Nc1ccccc1-n1cccc12 +CS(=O)(=O)c1ccc(NC2CCCCCC2)c(S(C)(=O)=O)c1 +CN(C(=O)NCc1ccc2c(c1)CCC2)C1CCC(CO)CC1 +CC(C)C(C(=O)N1CCOC(c2ccc(F)cc2)C1)n1cncn1 +COC(=O)CSc1nc2ccccc2n1CC(=O)NC(C)C +NC(=O)C1CCN(C(=O)c2ccc3c(c2)OCCO3)CC1 +Cc1nc2ccc(-c3cn4cc(N)ccc4n3)cc2[nH]1 +CCCn1c(NCCO)nc2sc3c(c2c1=O)CCCC3 +O=C(Nc1ccc2nc(N3CCOCC3)sc2c1)c1cnccn1 +COc1ccc(CNC(=O)CNc2ccc(C(N)=O)cc2)cc1O +COc1ccc(CNC(=O)c2csc(C)c2)cc1 +NC(=O)C1CCN(C(=O)Nn2cnc3ccccc32)CC1 +CC1CCC(NC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)CC1 +O=C(Nc1ncnc2c1CCC2)c1ccc2c(c1)OCCO2 +CSc1ncc(CNC(=O)c2cc(=O)[nH]c3ccccc23)n1C +COCc1cccc(C(=O)Nc2ccc(CN3CCCC3=O)cc2)c1 +CCc1cccc(C)c1NC(=O)c1[nH]c(C)c(C(C)=O)c1C +COc1ccc(-c2noc(COc3ncnc4sccc34)n2)cc1 +CCOC(=O)C1CCCN(S(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O)C1 +O=C(Nc1cnc(N2CCCC2)nc1)c1ccccc1 +Cc1cc(N)nc(SC(C)C(=O)NC2CCCC2)n1 +CN(Cc1cc(Br)cs1)C(=O)c1cccc(C#N)c1 +CN1CC(NC(=O)c2cnn(-c3ccccc3Cl)c2)CCC1=O +CCOc1ccc(NC(=O)NCCc2nccs2)cc1Cl +Cc1ccccc1CSc1nnc(C(C)C)n1N +Nc1c(NCc2ccccc2)ncnc1Oc1cccc2cccnc12 +Cc1ccc2oc(=O)n(CCC(=O)N3CCOCC(CO)C3)c2c1 +Cn1cccc1CN(Cc1cccs1)S(=O)(=O)c1cccnc1 +CC(C)C(O)CNC(=O)CNC(=O)c1ccc(Br)cc1 +CC(C)c1cc(C(=O)NCC2CCCN(c3ncccn3)C2)n(C)n1 +COCC(=O)Nc1cc(OC)c(OC)cc1Br +COc1ccc(Cl)cc1CNC(=O)CN1C(C)COCC1C +O=c1ccc(C(F)(F)F)cn1Cc1cc(=O)n2ccccc2n1 +Cc1nn(CCC(=O)NC(C)C)c(C)c1Br +Cc1cc(NC(=O)CCN2CCN(C(=O)CCC(C)C)CC2)no1 +COc1ccccc1NC(=O)C1CC(C)(C)OC1=O +O=C1Cc2cc(NC(=O)c3ccc(Cl)cc3O)ccc2N1 +CCc1nn2c(=O)cc(COC(=O)c3cc(C)no3)nc2s1 +CCc1nn(C)c(NC(=O)NCCc2nc(COC)no2)c1C +Cc1cccc2c1CC(C1OC(=O)c3ccccc31)C2=O +COc1cc(C)c(C)cc1S(=O)(=O)NCC(N)=O +O=C(Nc1cccc(F)c1)c1cc(F)cc(F)c1 +CCCS(=O)(=O)c1ccc(NCCOC)cc1 +CCc1cc(NC(=O)c2cnn(-c3ccccn3)c2C)[nH]n1 +Cn1c(=O)c2cn(-c3ccc(F)cc3)cc2n(C)c1=O +Cc1cccc(C)c1Oc1ccccc1NC(=O)NCCO +CC1(C)C(=O)OC(C(=O)c2ccccc2)C(C)(C)C1=O +Cc1cc(C)nc(-c2nc3c([nH]2)CC(C)(C)CNC3=O)n1 +COc1ccc(C(=O)N2CCN(CCn3cccn3)CC2)cc1 +CN(CC(=O)Nc1ccccc1)C(=O)CNC(N)=O +Cc1sc(C(N)=O)cc1S(=O)(=O)NC(C)(C)C +CC(C)Cc1n[nH]c(SCC(=O)Nc2nc3ccccc3s2)n1 +O=C(c1noc2c1COc1ccccc1-2)N1CCc2ccccc2C1 +NS(=O)(=O)NCC1(c2ccc(Cl)cc2Cl)CCOCC1 +O=C(c1ccc(-n2cnnc2)cc1)N1CCCC1Cn1cccn1 +Cc1cccc(OC2CCN(C(=O)c3cc4ccccc4o3)CC2)n1 +COCCNC(=O)c1cc(C(C)C)nc(N2CCCC2)n1 +O=C(NCc1nc(-c2ccccc2)cs1)c1ccc(F)cc1 +CC(C)OCCCNC(=O)NC1(C(F)(F)F)Oc2ccccc2O1 +CS(=O)(=O)c1ccccc1-n1cc(NCc2cccnc2)cn1 +O=C(CCC(=O)c1cccs1)Nc1cnn(CC(F)F)c1 +O=C(Nc1nccs1)c1cc2c(=O)c3ccccc3oc2o1 +Cc1cc(C)cc(CCNC(=O)Nc2ccc3c(c2)oc(=O)n3C)c1 +O=C(c1csc2c1CCCC2)N1CCC(N2CCNC2=O)CC1 +Cc1ccc(Cl)c(-c2nccn2CCN2CCNC2=O)c1F +Cc1cc(NC(=O)CSc2nnc(Cc3ccccc3)o2)no1 +CCc1cccc(C)c1NC(=O)Cn1nnc(-c2ccccc2)n1 +Cc1ccc(=NS(=O)(=O)c2cccc(C(=O)N3CCCC3)c2)[nH]c1 +C=CCN(Cc1ccccc1F)S(=O)(=O)c1ccc(C(N)=O)cc1 +CNc1nc(CNC(=O)Nc2ccnn2-c2ccccc2C)cs1 +Cc1cc(C(C)NC(=O)N2CCCC(C3(C)OCCO3)C2)c(C)o1 +COc1cccc(CCCNC(=O)NC2(CO)CCCC2)c1 +Cc1cc(Br)ccc1NC(=O)Cn1cnc(N)n1 +CC(C(=O)NC1CCCc2ccccc21)n1cc(Br)cn1 +CCn1c(-c2ccc(Br)cc2)ccc(CO)c1=O +O=C(NCCNc1cccnc1)c1c(O)cccc1O +Cc1ccc(NC(=O)N2CCOC(c3ccccc3)C2)c(C)n1 +Cc1nc(-c2ccccn2)ncc1Br +Cc1cnc(C(C)(C)NC(=O)Nc2nc3c(s2)COCC3)s1 +CCOCC(O)CN1CCN(C(=O)c2ccc(C)o2)CC1 +COc1ccc(CN(C(=O)C2COCCO2)C(C)C)c2ccccc12 +FC(F)(F)c1cnc(Sc2nc(C3CC3)n[nH]2)c(Cl)c1 +CCCCN(CC(F)(F)F)C(=O)c1cc2c([nH]c1=O)CCCC2=O +Cc1nc(N2CCC(c3ccnn3CCO)CC2)c2cnn(C)c2n1 +O=S(=O)(c1ccccc1)c1cc2ccccc2n2nnnc12 +CCOCCCNS(=O)(=O)c1ccc2c(c1)CCCN2C(C)=O +COC(C(=O)Nc1cc(C)cc2cccnc12)c1ccccc1 +CCOc1ccccc1C(=O)NCC1CCN(c2cnccn2)CC1 +CCCOc1ccccc1C(=O)N1CCC2(CCCN(C)C2=O)C1 +COC(=O)c1ccccc1S(=O)(=O)Nc1ccc(F)c(F)c1 +Cc1cc(C(=O)N2CCCCC2)c2cnn(C(C)C)c2n1 +CC(C(=O)NCc1cccnc1-n1cccn1)n1ccnc1 +CNS(=O)(=O)c1cccc(C(=O)NCc2ccccc2)c1 +O=C(NC1CCN(c2nccs2)CC1)c1c[nH]c2ccccc12 +CCc1nc2n(n1)CCCC2NC(=O)NCc1ccc(OC)c(C)c1 +CC(NC(=O)c1ccc[nH]c1=O)c1cc2ccccc2o1 +COCc1ccccc1C(=O)N1CCN(Cc2nc(C)c(C)o2)CC1 +CCCCc1noc(Cn2nc(-c3ccc(F)cc3)oc2=O)n1 +COCc1ccccc1NC(=O)C(C)Sc1nncn1C +Nc1cc(S(N)(=O)=O)ccc1-n1cc(Br)cn1 +CCCC(=O)NC1CCCN(c2ccc(C#N)nc2)C1 +COc1ccc(C(=O)N2CCCCCC2)cc1Br +CC(Sc1ccccn1)C(=O)N(C)C1CCCCC1 +CN(C)C(=O)CNc1ccc(Cl)cc1C(N)=O +CC(Oc1ccc(F)cc1Br)C(=O)N1CCNC(=O)C1 +OCCN1CCN(c2nc3ccccc3nc2-c2ccccc2)CC1 +COc1cc(F)c(NC(=O)NC(C(N)=O)C(C)(C)C)cc1F +CN(C)C(=O)c1ccc(CN2CCN(CC3CC3)c3ccccc32)[nH]1 +Cc1occc1C(=O)Nc1ccc(Br)c2cccnc12 +C#CCNC(=O)N1CCC(Oc2ccccc2)CC1 +CCOc1ccc(NC(=O)c2cnc(C)cn2)c(C(F)(F)F)c1 +Cn1c(C(O)(c2ccccc2)C(O)c2ccco2)nc2ccccc21 +CCC(C)n1ncc(C(=O)Nc2ncc(C(C)=O)s2)c1C1CC1 +COC(=O)c1c(NC(=O)c2csnn2)sc2c1CCCC2 +CN(Cc1ccccc1Br)c1nnnn1-c1ccccc1 +COc1ccc(F)cc1NC(=O)N(C)Cc1cn(C)nc1C(C)C +O=C(NCCCn1cccn1)c1ccc2ccccc2c1 +O=C1CCCN1Cc1nnc(SCc2cccc(F)c2)o1 +Cc1cc(C(=O)Nc2ccc3c(c2)NC(=O)CO3)on1 +O=C(c1cccc(=O)[nH]1)N1CCC(Cn2cc(C3CC3)nn2)CC1 +CN(C)c1ccc2c(Br)cnc(C#N)c2c1 +O=C(CNC1CCCN(c2cccnn2)C1)Nc1ccc(Cl)cn1 +Cc1csc(NC(=O)NC2CC(=O)N(c3ccccc3)C2)n1 +CC(C)NC(=O)Nc1ccc(-n2cncn2)c(C(F)(F)F)c1 +CC(=O)Nc1ccc(-c2cn3cc(Cl)ccc3n2)cc1 +Cc1ccc(N2CCC3(CC2)NC(=O)CC3c2cnn(C)c2)nn1 +CC1(C(=O)NCCc2ccc(F)cc2)Cc2ccccc2C(=O)O1 +CCC1CCN(C(=O)c2ccc3c(c2)CCN3)CC1 +COc1cccc(C2NCCc3ccc(OC)c(F)c32)n1 +CCc1ncsc1-c1nnc(NCC(C)C)s1 +Cc1ncnc2c1CCN(C(=O)C1CCCCC1)CC2 +COc1ccc(NC(=O)N2CCN(Cc3ccccc3C)CC2)cc1 +COc1ccc(Cc2cc(N)n(C)n2)cc1C(C)C +CC1CCC2(CC1)CN(CCO)c1ccc(Cl)cc1N2 +O=C(Cn1nnc2ccccc2c1=O)NCCc1ccccc1F +CCOC(=O)Nc1nc(CC(=O)NCc2cccnc2)cs1 +O=C(C1CCCN(c2ncnc3[nH]cnc23)C1)N1CCCCCC1 +CCOC(=O)C(N)Cc1c(C)ccc(C(C)C)c1OC +CCOC(=O)Cc1csc(NC(=O)CC2CC3CCC2C3)n1 +Cc1cccc(-c2nnc(COC(=O)C(C)NC(=O)C(C)(C)C)o2)c1 +CC(C)(CNC(=O)OC(C)(C)C)NC(=O)c1noc2c1CCCC2 +Cc1[nH]c2cc(-c3ccncc3)nn2c(=O)c1CCC#N +Nc1c(Br)cc(Br)c(F)c1F +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1cc2ccccc2oc1=O +COCCCNC(=O)Nc1cccc2c1CCCC2 +CC(CNC(=O)C1CC1c1ccco1)c1nc(-c2ccccc2)no1 +CCC(CC)NC(=O)Cc1coc2cc(OC)ccc12 +CCOc1ccc(F)c(C(=O)Nc2ccsc2C(=O)OC)c1F +COc1cccc(CC(=O)NCc2cccc(-c3nc(C)n[nH]3)c2)c1 +CN(CC1CCCCO1)c1cc(C(F)(F)F)nc2ncnn12 +O=C(c1ccc(=O)[nH]c1)N1CCCC1c1nc2ccccc2[nH]1 +COc1ncccc1N(C)C(=O)CCCc1cc(F)ccc1F +CS(=O)c1ccc(CNc2ccccc2OCC2CC2)cc1 +CCOC(=O)C1CCCN(C(=O)c2cc(C)sc2C)C1 +CCCCn1c(SCC(=O)N(C)C)nc2ccccc2c1=O +Cc1nc(C(C)NC(=O)C(O)c2cc(Cl)cc(Cl)c2)cs1 +Cc1ccc(NC(=O)NC(C)C)c(C)c1S(=O)(=O)NC1CC1 +COc1cccc(C(=O)Nc2cccc(S(C)=O)c2)c1OC +CS(=O)c1ccc(C(=O)OC2CCCCC2)cc1 +CC(C)Oc1ccc(C(N)=O)cc1Br +COc1ccc(Cl)cc1NC(=O)Cn1cnc2ccccc2c1=O +CSc1nc(N)c(S(=O)(=O)c2ccc(C)cc2)s1 +CCN1CCc2nc(NC(=O)CNC(=O)CC(C)(C)C)sc2C1 +CCCn1c(C)c(C)n2c3c(=O)n(C)c(=O)n(C)c3nc12 +COCCc1nnc2sc(-c3cccc(N)c3)nn12 +Cc1ccccc1SCC(=O)Nn1c(C)nc2sccc2c1=O +Clc1cccc(CNc2cccc3[nH]ncc23)c1 +Cc1ocnc1CNC(=O)Nc1ccc(CCN2CCOCC2)cc1 +Cc1ccc(OC2CCN(C(=O)Nc3cccs3)CC2)nn1 +O=C(Cc1ccccc1F)Nc1ccc(F)c(F)c1F +CCn1cc(C#N)c(=O)c2cc(F)c(N3CCCCCC3)cc21 +Cc1cc(C(=O)NCC(=O)Nc2ccccc2Br)no1 +CCOC(=O)C1=C(COC)Nc2ncnn2C1c1cccc(Cl)c1 +CC(C)c1nnc(NC(=O)Cc2ccc(Br)cc2)s1 +Cc1ccsc1C(=O)Nc1sccc1C(=O)NC1CC1 +COc1ccccc1C1CC(O)=Nc2c1cnn2C +Cc1cc(C)n2ncc(-c3noc(CN4CCCCCC4=O)n3)c2n1 +O=C1NCCCCC1NC(=O)N1CCCC1c1nnc2ccccn12 +N#Cc1cccnc1SCC(=O)Nc1ccc(Cl)cc1 +CCc1nc(CNc2cccc(C(=O)NC(C)(C)C)c2)cs1 +O=C(c1c[nH]nn1)N1CCCC(NS(=O)(=O)c2ccccc2)C1 +Cc1cccc(NC(=O)c2ccccc2S(N)(=O)=O)c1 +CCN(c1ccncc1)S(=O)(=O)c1cccc(Cl)c1C#N +O=C(Nc1cccn2c(C3CCC3)nnc12)C1CCCO1 +CC(Cc1ccccc1F)NC(=O)C(NC(=O)c1ccco1)C(C)C +Cc1n[nH]c(C2CN(CC(O)c3ccc(F)cc3F)CCO2)n1 +O=C(Cc1ccccc1)N1CCN(C(=O)c2cnc3ccoc3c2)CC1 +CS(=O)(=O)N1CCN(C(=O)Cn2cnc3ccccc32)CC1 +CN(C)c1ccccc1C#CCNC(=O)NCc1ccc(F)cc1 +Cc1cccc2sc(NCc3ccncc3)nc12 +CCCC(C)(CO)NC(=O)NCc1ccc(C(N)=O)o1 +Nc1cccc(CC2Oc3ccccc3NC2=O)c1 +CC(C)Cc1nnc(NC(=O)NCc2nnc3n2CCCCC3)s1 +CCc1ccc(NC(=O)c2ccc(S(N)(=O)=O)cc2)cc1 +COc1ccc(CC(C)CNC(=O)c2scnc2C)cc1 +NC(=O)N1CCCC(C(=O)NC2c3ccccc3-c3ccccc32)C1 +O=C(Nc1nncn1Cc1ccccc1)c1ccccc1-n1ccnn1 +Cc1ccc(S(=O)(=O)Oc2ccc3c(c2)CCC(=O)N3)cc1C +Cc1cc(C)n2ncc(C(=O)N3CCC(OCC(C)C)CC3)c2n1 +COc1ccc(-c2nc(C(=O)Nc3cc(OC)ccn3)cs2)cc1 +COc1ccc(OCCNC(=O)N2CCOC(C)(C)C2)cc1 +CCN1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 +CCCOc1cc2c(cc1OC)CCNC2C1CC(=O)C1 +CCc1noc(CN(C)C(=O)C(C)Sc2ccccn2)n1 +Cc1cc(C(=O)N2CCC(O)(C(F)(F)F)CC2)sc1C +CCC(=O)NC1(c2ccc3c(c2)OCCO3)CCCC1 +CCOc1ccc(NC(=O)Cc2coc3ccc(F)cc23)cc1 +COc1ccc(NC(=O)Cc2ccc[nH]2)c(C(=O)NC2CC2)c1 +CCCNC(=O)COc1ccc(C(=O)NC2CC2)cc1N +CCN(CC(=O)NC(C)C)C(=O)c1cccc(C)c1C +Cc1cc(Cl)ccc1NC(=O)Cn1cc(N)ccc1=O +O=C(COCc1cc(-c2cccs2)on1)N1CCCCCC1 +COc1cccc(C(=O)N2CCN(C3=NC=NC4=NC=NC43)CC2)c1 +O=C(CC1CCN(C(=O)Nc2ccccc2)CC1)N1CCCCC1 +O=C1CCc2ccc(NC(=O)c3c(O)cc(F)cc3F)cc2N1 +CN(C)c1ccc(C(=O)NCCCn2ccc3ccccc32)cc1 +CCCCn1nc(-c2cc(F)ccc2OC)cc(C#N)c1=O +CCC(C)NC(=O)NCc1cn2ccsc2n1 +CC(C)Nc1cccc(CNC(=O)c2cccc(-n3cncn3)c2)c1 +CCN(CCc1ccccc1)C(=O)CNC(=O)c1cccc(C)c1 +CCn1cc(-c2nc(C)nn2CC(F)(F)F)cn1 +O=S(=O)(NCc1cccc(O)c1)c1ccc(F)cc1F +CCCNC(=O)CN(C)S(=O)(=O)c1cccc(C#N)c1 +Cc1ccc(NC(=O)CCCNC(=O)c2ccco2)cc1C +CC1CN(CCc2cccc(Br)c2)CC(C)O1 +Cc1ccc2ncc(C(=O)N(C)c3cccc4ncccc34)n2c1 +Cc1cc(=O)c(C(=O)N2CCCCCC2)nn1-c1ccccc1 +Cc1nc2c(N)cccc2n1CC(=O)Nc1ccc(F)cc1 +Cc1occc1C(=O)NC(C)c1csc(C(C)C)n1 +Cc1cccc(CSc2n[nH]c(=O)n2C2CC2)c1 +Cc1ccccc1COC1CCN(C(=O)Cn2cnnn2)CC1 +CCN(CC)C(=O)c1sc(NC(=O)C2CCCC2)cc1C +Cn1c(N)c(C(=O)CSc2ncn[nH]2)c(=O)n(C)c1=O +Cc1cccc(COC2CC3CN(Cc4cnn(C)c4)CCN3C2)n1 +O=C(c1ccncc1)N1CCC(c2nnc(-c3ccncc3)o2)C1 +Cc1ccc(=O)n(C(C)C(=O)Nc2ccccc2-c2ccccc2)n1 +CS(=O)(=O)NCCC(=O)Nc1ccc(Oc2ccccc2)cc1 +COC(=O)c1cccc(C(=O)Nc2ccccc2N(C)C)c1 +Cc1ccccc1-n1ccnc1SCc1ccccn1 +C#CCN1CCC(C(=O)Nc2ccc3oc(C)nc3c2)CC1 +CN(Cc1cccc2cnccc12)C(=O)c1cnn2ccccc12 +O=C(NCC(N1CCC1)C(F)(F)F)OCc1ccccc1 +CCCCNc1ncnc2c1cnn2-c1ccc(C)cc1 +Cc1ccc(O)c(-c2cc(C(=O)OC(C)C)no2)c1 +CNC(=O)c1cc(S(=O)(=O)NCCN2CCOCC2)ccc1C +O=C(NCc1ccnc(OCC(F)(F)F)c1)c1ccccc1 +Cc1nc(CNC(=O)CCn2cnc3ccccc3c2=O)c(C)s1 +CC(C(=O)N(C)C)N1CCN(C(C)C(=O)N2CCCC2)CC1 +COCC(=O)Nc1cccc(NCc2cncs2)c1 +CC(=O)Nc1cccc(C(=O)NC2CCCNC2=O)c1 +N#Cc1cccc(NS(=O)c2ccc(N)cc2)c1 +COCCCC1CCCCN1C(=O)c1cccc2cc(C)oc12 +CN(C)C(=O)CCCC(=O)Nc1ccc(Cl)cc1 +Cc1ccc(S(=O)(=O)n2ccc3c2C(=O)CC3(C)C)cc1 +Cc1nsc(N2CCN(Cc3cncs3)CC2)n1 +Cc1nn(C)c(C)c1CCC(=O)NCc1nc2ccccc2[nH]1 +CCn1cc(NC(=O)Cn2cc(-c3cc(C)nc(NC)n3)cn2)nn1 +NC(=O)c1ccc(S(=O)(=O)N2CCSc3ccccc32)cc1 +CCOC(=O)C(C)NC(=O)c1c(Cl)cccc1Cl +CCCNC(=O)c1nc(CCS(=O)(=O)c2ccc(C)cc2)no1 +Cc1cc(C)nc(NC(=O)C2CC(=O)N(C3CCCC3)C2)n1 +COCC(C)(O)CNS(=O)(=O)c1cccnc1 +O=C1NCCN(CC2CCOC2)C1c1ccccc1C(F)(F)F +CCCNC(=O)C(C)NC(=O)Nc1c(C)cccc1CC +Cc1ncc(CNC(=O)c2cnc3sccn3c2=O)s1 +Cc1cccc(C(=O)N2CCc3cc(F)ccc3C2)n1 +O=C(NCc1ccccc1)c1ccc2ncnn2c1 +Cc1nc(C)c(C(=O)Nc2ccccc2C(=O)NC(C)(C)C)s1 +COC(=O)C(C)NC(C)c1cccc(OC(F)F)c1 +COc1cc(C(=O)NCCN2CCOCC2)ccc1OC(C)C +CC1CCN(c2nc(SCC(N)=O)c(C#N)c3c2CCCC3)CC1 +CC(NC(=O)c1ccccc1)c1nc2ccccc2n1C(C)C +COC(=O)c1cccc(Cc2cnc(NC(=O)C3CCOC3)s2)c1 +CS(=O)(=O)c1ccc(-c2csc3nc(N)cn23)cc1 +CCC(C)NC(=O)C(C)Oc1ccc(Cl)cc1 +CCCN1C(=O)C(O)(CC(=O)c2ccccn2)c2ccccc21 +O=C(NCC1CC1)C12CC(CN1Cc1nccs1)C2 +O=C(NCC1CCCO1)c1cccc(N2CCNC2=O)c1 +COc1cccc(CNC(=O)CNC(=O)NCc2ccccc2)c1 +O=C(c1cc2ccccc2c(=O)[nH]1)N1CCCC1c1ccsc1 +CCc1nnsc1C(=O)N1CCCC(n2cc(C)cn2)C1 +O=C(c1cc2occc2[nH]1)N1CCN(CCc2ccccc2)CC1 +Cc1csc2ncc(C(=O)NCCc3ccccc3)c(=O)n12 +O=C(COc1ccccc1)Oc1ccc2ccc(=O)oc2c1 +CC(C)(C)c1nc(CNC(=O)NCC(C)(C)c2ccncc2)cs1 +c1ccc2sc(-c3ccc(Cn4cnnc4)cc3)nc2c1 +Cc1cccc(-c2noc(C3CCN(C(=O)N(C)C)CC3)n2)c1 +Clc1cc(Br)ccc1CN1CCCC2(C1)OCCO2 +O=C1CC(CO)CN1c1cc(Cl)cc(Cl)c1 +O=C(Nc1cccnc1N1CCCCC1)c1ccsc1 +O=C(Cc1cccs1)NCCn1nnn(-c2ccccc2)c1=O +O=C(NCc1ccccc1F)NCC1Cc2ccccc2O1 +O=C(CNC(=O)c1cnc2ccoc2c1)Nc1cccc(Cl)c1 +O=C(NC1CCN(c2cccc(F)c2)CC1)N1CCCCC1CCO +CCCOc1ccc(Cl)cc1NC(=O)NCCNC(C)=O +Cc1c(C(=O)N2CCN(c3ccccc3Cl)CC2)cnn1C +C#CCN1CCN(C(=O)NC2CCCC(C(=O)NC(C)C)C2)CC1 +CC(=O)c1ccc(NC(=O)c2nc3nc(C)cc(C)n3n2)cc1C +COc1ccccc1CNC(=O)c1nc2ccccc2c(=O)[nH]1 +CCOC(=O)N1CCN(C(=O)c2n[nH]c3c2CCCC3)CC1 +CC(NC(=O)c1ccncc1)c1cc2ccccc2o1 +CCC1CN(C(=O)C(C)NC(=O)OC(C)(C)C)CCO1 +CC1CN(Cc2ccc(OC(F)F)c(Cl)c2)CC(C(N)=O)O1 +Cc1n[nH]c(C(=O)N2CCCC(c3ccn[nH]3)C2)c1Br +CCCn1ncc(C(=O)NCC(O)c2ccccc2Cl)c1C +Nc1cc(N2CC3CCC(C2)N(Cc2ccccc2)C3=O)nc(N)n1 +CC1(NS(=O)(=O)N2CCCCCC2)CCCC1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(C(F)(F)F)cc1 +Cc1ccc(NC(=O)C(C)n2nc(C)cc2C)c(F)c1 +CC(=O)Nc1ccc(-c2csc(-c3cnccn3)n2)c(F)c1 +COc1ccc(Cl)cc1C(=O)NC(C)c1nnc2ccccn12 +CCOC(=O)C(C)NC(=O)NCC(=O)N1CCc2ccccc21 +O=C(COC(=O)c1ccc(O)cc1)NCc1ccccc1Cl +CCOC(=O)c1ccc(NCc2ccncc2)cc1 +CCn1cc(C(=O)N2CCCC2C(=O)N2CCN(C)CC2)cn1 +Cc1cc(C(C)(O)CNC(=O)CC2(O)CCCCC2)c(C)o1 +COc1ccc(Cl)cc1CC(=O)N1CCN(CC(C)O)CC1 +O=c1oc(=C(Cl)Cl)[nH]c1=Cc1ccccc1 +Cc1cccc(N2CCN(C(=O)NCCc3nccs3)CC2)c1C +O=c1[nH]c(Cc2ccc3c(c2)OCO3)nc2ccc(F)cc12 +COC(=O)CC1CCN(C(=O)OCc2ccccc2)CC1 +Nc1ncnc2c1sc1nc(-c3ccccc3)ccc12 +N#Cc1ccccc1N1CCCN(CC(O)CN2CCOCC2)CC1 +CCC(C)Oc1ccc(NC(=O)c2cccc(NC(C)=O)c2)cc1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NC2CCCCC2)[nH]n1 +O=C(COc1ccc2ccc(=O)oc2c1)c1ccc2c(c1)OCCO2 +CCCS(=O)(=O)NCc1cc(F)cc(Br)c1 +Cc1nn(CCO)cc1-c1c(C#N)c(N)nc2c1Cc1ccccc1-2 +Cc1ccc(N2CC(C(=O)N3CCC(C)C3C)CCC2=O)cc1C +Cc1ccc(CCNS(=O)(=O)c2ccc(C(F)(F)F)nc2)cn1 +CC(CC(=O)NC1CC(=O)N(C)C1)c1ccc(C(F)(F)F)cc1 +Cc1cc2occ(CC(=O)N(C)C)c2cc1C(C)C +O=C(NCc1ccc2c(c1)OCCO2)c1ccnc(-n2ccnc2)c1 +CCCNC(=O)C(C)NC(=O)c1nc(C)n(-c2ccc(Cl)cc2)n1 +CN(C)S(=O)(=O)NC1CCN(c2ccc(F)cc2)CC1 +Fc1ccc(C(CC(F)(F)F)NCc2cccs2)cc1 +CC(C)CN1CC(C(=O)NCCN2CCOCC2)CC1=O +Cc1nccn1-c1ncccc1NC(=O)C(C)OCC(C)C +Cc1cc(Cl)ccc1Nc1nc(C)c(CCO)c(=O)[nH]1 +CN(Cc1nc2ccccc2[nH]1)C(=O)Nc1cn[nH]c1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2c(C)cccc2C)c1 +CCC1c2ccccc2CCN1C(=O)c1cccn1C +COC(=O)c1ccc(C)c(NC(=O)c2ccc3ccccc3n2)c1 +O=C(Nc1cc(-c2ccc(F)cc2)no1)c1ccccc1F +CS(=O)(=O)NCCNC(=O)c1cn(-c2ccccc2Cl)nn1 +CCC(NC(=O)C(C)C)c1ccccc1OCC(=O)N1CCCC1 +CCN(CC)C(=O)CN1CCN(c2ccc(F)c(F)c2)C1=O +O=C(CC1CC2CCC1C2)NC1CCN(C(=O)c2cnccn2)CC1 +CCCC1CN(C(=O)C(C)Oc2ccccc2)CCO1 +Cc1nnc(-n2nnc(CO)c2-c2cccc(F)c2)s1 +COCCN(CC(F)(F)F)C(=O)c1cc2ccccc2s1 +COc1ccc(C(=O)CCC(=O)Nc2cccnc2)cc1 +CC(C)CC(=O)NCCn1ncc2c(N3CCCCC3)ncnc21 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCc1csc(C)n1)O2 +Cc1ccsc1CNC(=O)Cn1ccc(C(F)(F)F)n1 +COc1ccccc1C1NC(=O)NC2=C1C(=O)N(CCC(C)C)C2 +Cc1cccc(C(=O)NCc2nc3ccccc3s2)c1 +CCC1CCCCN1C(=O)c1cccc(Oc2ncccn2)c1 +O=C(Cc1c(Cl)cccc1Cl)NCCCn1cccn1 +CC1(C)Oc2cc(S(=O)(=O)N3CCCCC3)ccc2NC1=O +O=C(NCc1nnc2n1CCC2)Nc1cc(Cl)ccc1F +CCc1cc(C#N)c(NC(=O)COc2cccc(OC)c2)s1 +Nc1cccn2c(-c3ccc(F)c(F)c3F)nnc12 +O=C(NC(C(=O)Nc1ccccc1)c1ccccc1)C1CC=CC1 +COc1ccc(C(=O)OC(C)c2nccs2)cc1-c1ccccn1 +Cc1ccc(CC(=O)Nc2cccc(OCC(=O)N(C)C)c2)s1 +C=CCNC(=O)c1ccc(C)c(Br)c1 +Cn1ccnc1C(NC(=O)NC1CCC(O)CC1)c1cccc(F)c1 +O=C(CC1C=CCC1)Nc1cccnc1-n1cccn1 +CCC(C)NC(=O)CCC(=O)c1ccc(OC)c(C)c1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1ccc(C#N)cc1 +C#Cc1cccc(NCc2cccc(OCCOC)c2)c1 +CCOC(=O)CN1CCCC(C(=O)OC(C)(C)C)C1=O +Cc1cccc(C(C)CNC(=O)COc2cccc(C(N)=O)c2)c1 +CC(C)C(C)NC(=O)Nc1nnc(-c2ccsc2)s1 +Cc1noc(-c2cccs2)c1C(=O)NCCc1ccc(F)cc1 +Cc1ccc(N2C(=O)c3cccnc3C2CC(=O)NC2CCCC2)cc1 +CCc1cc(C2CCCN2C(=O)Nc2cc(OC)ccc2OC)on1 +CC(CNC(=O)Cn1cnnn1)N1CCc2ccccc21 +O=C(CCCNC(=O)C1CC1)Nc1nc(-c2ccccc2F)n[nH]1 +CCOC(=O)N1CCN(C(=O)CCNC2=NC=NC3=NC=NC32)CC1 +O=C(CSc1cccs1)Nc1cccc(CO)c1 +O=C(NC1CCN(C(=O)c2ccncc2Cl)CC1)c1ccncc1 +CC(C)Cn1ncc2cc(C(=O)N3CCOCC3C3CC3)cnc21 +CS(=O)(=O)NCCCNS(=O)(=O)c1ccc2c(c1)CCC2 +O=C(CCCC(=O)c1ccc(F)cc1)NCc1ccncc1 +Cn1nccc1C(=O)Nc1ccccc1CCc1nc2ccccc2[nH]1 +N#Cc1ccc(Cl)c(NC(=O)c2csc(-c3ncccn3)n2)c1 +N#Cc1ncn(CC(=O)N(CCC(N)=O)Cc2ccccc2)n1 +CC(CO)NC(=O)C(C)Oc1ccc(Cl)cc1Cl +Cc1noc(C)c1CCCNC(=O)NCC1CCCc2ccccc21 +Cn1c(=O)c2c(-c3ccc(Cl)cc3)n(NC(N)=O)cc2n(C)c1=O +CCN(C(=O)Cn1cc(C)c(N)n1)c1ccccc1 +CCC1CCC(CNC(=O)NCc2ncn(C)n2)CC1 +COc1cccc(OC)c1CNCCN1CCOCC1 +CCOc1cc(C(=O)N2CC(C)OC(C)C2)nn1-c1ccccc1 +COC(=O)CSc1nnc(-c2ccoc2C)n1-c1cccc(C)c1 +Cc1cccc(NCC(=O)N2CCN(C(=O)C3CC3)CC2)c1C +NC(=O)N1CCCC(C(=O)NCCc2nc3c(s2)CCCC3)C1 +CSc1ncccc1C(=O)N1CCCCCC1 +CCC(CO)N(Cc1ccc(C)s1)C(=O)c1occc1C +O=C(CCn1ncc(=O)c2ccccc21)Oc1ccc2c(c1)CCC2 +CC(NC(=O)NCc1nnc2n1CCC2)c1ccccn1 +CCc1onc(C)c1NC(=O)Nc1cnn(CC(C)C)c1 +COC(=O)N(C)CC(=O)N1CCC2C(CCC(=O)N2C2CC2)C1 +CN1CCN(C2CCN(C(=O)c3ccccc3)CC2)C(=O)C1=O +Cn1c(SCc2ccccc2F)nnc1C(O)c1ccccc1 +Cc1cn(C)nc1C(=O)c1cc(S(C)(=O)=O)co1 +C#CCNC(=O)CNC(=O)C(Oc1ccccc1)c1ccccc1 +C=CCNC(=O)CN1CCc2nc(NC(=O)OCC)sc2C1 +O=C(c1cn(-c2ccccc2)nn1)N1CCOCC1C1CC1 +COc1ccc(CNC(=O)Cn2c(CO)nc3ccccc32)cc1 +Cc1ccc(CNC(=O)CN2C(=O)CSc3ccccc32)n1C +N#Cc1ncn(Cc2csc(-c3ccsc3)n2)c1C#N +COc1ccccc1C(C)NC(=O)Cn1c(=O)n(C)c2ccccc21 +CCc1ccccc1N1CC(C(=O)NCCO)CC1=O +Cn1c(=O)[nH]cc(C(=O)Nc2ccccc2C(N)=O)c1=O +Cc1cccc(C(CC(=O)N2CCc3sccc3C2)NC(N)=O)c1 +O=C1CC(O)Cc2nc(-c3cscn3)sc21 +O=C(c1cnn(-c2ccc(F)cc2)n1)N1CCCCC1 +COCCCNC(=O)c1cc(S(N)(=O)=O)ccc1F +Cc1ccsc1CN(C)C(C)c1cccc(O)c1 +Cc1nn(C)c2ncc(C(=O)NCC(C(C)C)N3CCOCC3)cc12 +COc1ccccc1SCC(=O)N(C)C1CCC(C)CC1 +O=C(NCCCn1ccc2ccccc21)NCCc1ccccn1 +CCc1onc(C)c1NC(=O)NCC1(c2ccc(F)cc2)CCC1 +COc1cc(Cl)c(C(=O)Cn2cccn2)cc1Cl +N#Cc1c(-c2cccs2)nc2sc(-c3ccco3)nn12 +N#Cc1cccc(S(=O)(=O)NCC2CN3CCCCC3CO2)c1 +CCOc1ccccc1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(CNC(=O)NCC1CC=CCC1)NCC(F)(F)F +COc1ccc(-c2nc3c(Cl)cccn3c2N)cc1 +O=S(=O)(NCc1cccc(Br)c1)c1cccs1 +CCNC(=O)c1nc(CS(=O)(=O)c2ccc(Cl)cc2)no1 +O=C(c1cccc2c1OCCO2)N(CCO)CCc1ccccc1 +Cc1cc(CNC(=O)c2cccc(N3CCCC3=O)c2)c(C)o1 +Cc1cc(C(=O)COC(=O)c2cc[nH]n2)c(C)n1C1CC1 +CC(C)C(NC(=O)CNc1ccc(C(N)=O)cc1)c1ccccc1 +O=C1COc2cc(C(=O)N3CCCC3Cc3ccccc3)ccc2N1 +CC(C)(C)c1nc2cccnc2n1Cc1cccnc1N +COC(=O)N1CCC(NC(=O)NCC(C)N(C)c2ccccc2)CC1 +COc1ccccc1NC(=O)c1cc(O)cc(OCC(F)(F)F)c1 +OC(CCc1ccccc1)CCC1C(O)CC2OC(O)CC21 +CC(O)(CNC(=O)Cc1cccc2ccccc12)C1CC1 +CC(Cc1ccsc1)NC(=O)N1CCc2ccccc2C1CO +CNC(=O)c1cc(C)ccc1NC(=O)c1cnn(-c2ccncc2)c1C +CC(C)(C)c1nnsc1C(=O)Nc1ccc2[nH]ncc2c1 +CCc1ccc(C(=O)Nc2ccc(SC)cc2)o1 +CCC(Oc1ccccc1F)C(=O)Nc1cc(OC)ccn1 +COc1cccc(NC(=O)NCc2nnc3n2CCCCC3)c1 +Cc1nc(CNC(=O)CCc2ccccn2)oc1C +Cc1ccccc1Cn1ccn(-c2cccc(Cl)c2)c(=O)c1=O +Cc1nn(-c2cncc3nnnn23)c(C)c1Br +CCCn1c(SCC(=O)CC)nc2cc(S(N)(=O)=O)ccc21 +C=CCNc1ncnc(Nc2ccccc2CC)c1N +CSc1cc(C)ccc1CNC(=O)c1ccc(-n2ccnn2)cc1 +CSc1ncc(CO)n1Cc1ccc(Cl)cc1 +Cc1c(N)cccc1C1CCCN1C(=O)OC(C)(C)C +CCN(Cc1ccccc1)S(=O)(=O)c1ccc2[nH]c(=O)ccc2c1 +Nc1ccccc1-c1nc2ccc(F)c(F)c2n1N +c1cnc(-n2cc(NCc3cccc(OC4CCCC4)c3)cn2)nc1 +CCN(CC(=O)N1CCC2(CC1)OCCO2)c1ccc(F)c(F)c1 +CN(Cc1cc[nH]n1)c1nc(-c2ccncc2)nc2c1cnn2C +Cc1[nH]ncc1CCCNC(=O)NC(C)c1ccncc1 +COc1cccc(CNC(=O)c2cc3c(cn2)OCC3)c1 +CC(C)C(=O)Nc1cccc(NC(=O)N2CCOCC2C2CC2)c1 +COCC(=O)N1CCC(NC(=O)NC2CCCC2)CC1 +CCc1ccc(S(=O)(=O)N2CCc3cc(N)ccc32)s1 +COCC(=O)Nc1cccc(NS(C)(=O)=O)c1 +Cc1ccc(NC(=O)NCc2ccn(C)c2)cc1S(C)(=O)=O +CN(Cc1ccsc1)C(=O)COc1ccccc1O +O=C(COc1ccccc1O)NCC1(N2CCOCC2)CCCCC1 +Cc1occc1C(=O)Nc1cnc2c(c1)c(C)nn2C +COc1ccc(S(N)(=O)=O)cc1C(=O)OCC1CCCCC1 +Nc1cc(Cl)ccc1NC(=O)CN1CCCCCC1=O +Cc1ccc(SCCNC(=O)c2cccnc2-n2cncn2)cc1 +CCOCCNC(=O)N1CCN(C(=O)c2cccc(O)c2)CC1 +CCOC(=O)CC(NC)C(=O)c1ccc2[nH]c(=O)oc2c1 +CCOC(CC)C(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +N#Cc1c(-c2ccc(C3CCCO3)s2)cc(-c2ccco2)nc1N +C=CCc1cc(C(=O)N2CCCC(CC)(CO)C2)ccc1OC +CCC(C)(C)NC(=O)C(C)N1CCN(S(N)(=O)=O)CC1 +CCC1CN(C(=O)c2ncoc2C2CCCO2)CC1N1CCOCC1 +CSc1nc2ncc3c(n2n1)CC(c1ccccc1C)CC3=O +COc1ccc(Nc2ncnc(-n3ccnc3)c2N)c(OC)c1 +O=C(Nc1ncnc2sccc12)c1ccc(Cl)cc1 +CC(C)CNc1nc(-c2c3c(n[nH]c2=O)CCC3)cs1 +Cc1cc(=O)n2nc(N3CCCC(C(=O)NC(C)C)C3)sc2n1 +CC1(C(=O)NCCc2ccccc2Cl)Oc2ccccc2NC1=O +Cc1nc(CSc2nc(-c3cccnc3)n[nH]2)cs1 +COc1ccc2ncnc(NCc3ccccc3)c2c1 +COc1c(O)ccc2c1C(c1cncn1C)NCC2 +Cc1nc(SC(C)C(N)=O)n(C2CCCCC2)c1C +N#Cc1ccccc1Sc1ccccc1C(=O)N1CCCCC1 +Cc1ccsc1C(=O)Nc1cc(Cl)ccc1C#N +Cc1c(Sc2nnc(C(C)C)n2C2CC2)c(=O)[nH]c2ccccc12 +CCOc1ccccc1-n1c(-c2ccn(C)n2)n[nH]c1=O +CC(=O)c1cccc(OCC(=O)Oc2ccccc2)c1 +Cc1ccc2nc(SCC(=O)c3ccc4c(c3)OCCO4)[nH]c2c1 +O=C(OCc1ccccc1)C1CCCN(C(=O)C2CC2)C1 +Cc1c(Nc2nc3nonc3nc2N)c(=O)n(-c2ccccc2)n1C +CCOC(=O)c1[nH]c2ccc(OC)cc2c1NC(=O)N1CCOCC1 +O=C1CCC(COC(=O)COc2ccc3c(c2)CCC3)N1 +NS(=O)(=O)c1ccc(C(=O)Nc2ccc(-c3nccs3)cc2)o1 +O=C(Nc1ccc(CC(=O)N2CCCC2)cc1)NC1CC1 +N#CCCN(CCN1CCOCC1)C(=O)c1cccs1 +Cc1cc(C(=O)NCCCC(N)=O)c(C)n1Cc1cccs1 +Cc1cc(NC(=O)c2ccc3ncsc3c2)sn1 +N#Cc1cc(C(=O)Nc2ccccc2)c(F)c(F)c1F +COc1ccc(C(=O)NC(C)c2nc3ccccc3[nH]2)c(OC)c1 +Cc1noc(C(NC(=O)Cc2cccc(OCC#N)c2)C(C)C)n1 +C#Cc1cccc(NC(=O)Nc2cccc(N3CCNC3=O)c2)c1 +Cc1ccc(NC(=O)COc2ccc(S(C)(=O)=O)cc2)cc1C +Cc1cc(NC(=O)c2cnc(Cc3ccccc3)s2)no1 +Cc1nn(C)c(C)c1CC(=O)N(C)C1CCCCC1C +COc1cc(Cl)ccc1C(=O)Nc1nc(C(N)=O)cs1 +Cc1ccnc(SCC(=O)c2cccs2)n1 +CCn1ccnc1CN1CCCN(C(=O)c2ccncc2)CC1 +Cc1ccc(S(=O)(=O)NC(C)c2nc(C)no2)c(F)c1 +CS(=O)(=O)c1ccc(NC(=O)N2CCc3ccccc32)cc1 +CC1CCCC(NC(=O)CS(=O)(=O)c2nncn2C)C1C +CC(C)c1cccc(OS(=O)(=O)c2cccnc2)c1 +CC(C)CN(C)C(=O)Nc1cccc(-n2cnnn2)c1 +Cc1cc2c(=O)n(C(C)C(=O)Nc3ccccc3)cnc2s1 +CCc1ccc(NCC(=O)Nc2nnc(C(C)C)s2)cc1 +O=C(Nc1cc(F)ccc1Cl)c1ccc2c(c1)OCO2 +CN(C)C(=O)c1ccccc1NC(=O)Cc1cc(-c2ccccc2)on1 +Cc1cc(=O)oc2cc(NC(=O)NCCC(=O)N3CCCC3)ccc12 +O=C(CN1CCN(CC(=O)N2CCOCC2)CC1)NCC1CCC1 +COc1ccc(CCC(=O)N2CCCc3ccc(F)cc32)cc1OC +Cc1ccccc1CC(C)NC(=O)CN1CCn2c(nn(C)c2=O)C1 +CCN1CC(C(=O)NCCCn2nc(C)cc2C)CC1=O +CCc1nc2nc3c(c(NCc4ccc(F)cc4)n2n1)CCC3 +CC1(C)C2CCC1(C(=O)NC1CCCCC1)C(=O)C2 +CC(NCCCN1CCOCC1)c1ccc(Cl)cc1 +COC(=O)C(C)(C)NC(=O)c1occc1Br +O=C1CC(c2nc(-c3ccccc3)no2)C2(CCCC2)O1 +NC(=O)CC1CCN(C(=O)Cc2cccs2)CC1 +COc1cc2oc(=O)cc(C)c2cc1CCC(=O)Nc1ccncc1 +COc1ccc(-c2cc(C#N)nn2CCCO)c(OC)c1 +CCOc1ccc(S(=O)(=O)N(C)CC(=O)NC(C)(C)C)cc1C +NC(=O)C(OC(=O)Cc1ccc2c(c1)OCCO2)c1ccccc1 +CC(=O)c1ccc(-c2nc3ccsc3c(=O)[nH]2)cc1 +CC(C)OCc1cccc(NC(=O)N2CCN(CC(F)F)CC2)c1 +CC1CCC(N(C)C(=O)NCc2nnc3n2CCCCC3)CC1 +COC(=O)CCCN(C)C(=O)c1cccn1C(C)C +O=C(Nc1cccc(-c2cn3ccsc3n2)c1)c1ccncc1 +CC(C1CC1)N(Cc1ccccc1)C(=O)CN1CCOCC1C1CC1 +N#CCc1sc(CSc2ccccc2)nc1C1CC1 +COC(=O)C(C)N(C)CCOc1ccc(Cl)cc1 +COc1cccc(CNC(=O)C2CCCN(C(=O)NC3CC3)C2)c1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)NCc1ccccc1Cl +COc1cc(C)c(S(=O)(=O)N2CCCN(C(C)=O)CC2)c(C)c1 +CCN(Cc1ccc(OCC#N)c(OC)c1)c1ccccc1 +O=C(CC1CCCCC1)NCCNC(=O)c1ccnc2cccnc12 +Cc1cccc(C(C)C)c1NC(=O)c1cccc(F)c1N +COc1ccccc1C(=O)CCC(=O)N1CCN(C)CC1 +Cc1c(NCC(=O)N2CC(C)OC(C)C2)cccc1C(N)=O +CC(C)CC1COCCN1CC(=O)N1CCOC2CCCCC21 +Cc1noc(CCC(=O)N(C)Cc2ccc(C)o2)n1 +CCc1cccnc1NC(=O)c1ccc(=O)[nH]c1C +Cc1ccc2nc(N3CCCCCC3)c3nnnn3c2c1 +CCOc1ccc(OCC(=O)Nc2ccccc2OC)cc1 +Cc1ccn2c(CN3CCN(C(=O)CC(F)(F)F)CC3)cnc2c1 +Cc1cccc2[nH]c(C(=O)N3CCN(C)CC3)nc12 +Cn1nc(Nc2ccc(Cl)cc2O)c(N)nc1=O +O=C(NCc1cccnc1)c1cc(N2CCCC2=O)ccc1Cl +O=C(C1CC=CCC1)N1CC=C(c2c[nH]c3ncccc23)CC1 +COc1cc(OC)cc(C(=O)NCCOc2ccc(C)cc2)c1 +CC(C)C(=O)NCc1cnn(-c2ccc(C(=O)NC(C)(C)C)cc2)c1 +CC(=O)Nc1c(C(=O)C2CC2)oc2ccc(Cl)cc12 +CNc1ccc(C)c(N(C)S(=O)(=O)N(C)C)c1 +Cc1c(C(=O)N2CC(C)OC(C)C2)oc2c(F)cccc12 +CC(Oc1ccccc1)C(=O)Nc1nc(C2CC2)cs1 +O=C(Cn1nc(-c2ccccc2F)ccc1=O)N1CCCCCC1 +C=C(C)CC1CCC(=O)N1Cc1ccc(OC)cc1 +CCCNC(=O)c1cccc(NC(=O)CCn2cc(C)cn2)c1 +CCC(=O)N1CCc2c3n(c4ccccc24)C(=O)CCC31 +CC(C)NC(=O)CCCOc1ccc(Cl)cc1 +CCN1C(=O)c2ccccc2Sc2ccc(N)cc21 +O=C(Nc1cnccn1)c1cccc(S(=O)(=O)N2CCCC2)c1 +O=C(C1CC1)N1CCCC(C(=O)N2CCCc3c(F)ccc(F)c32)C1 +Cc1ccc(OC(=O)CCC(=O)N2CCCC2)cc1 +N#Cc1cccc(-c2nncn2-c2ccc(Cl)cc2)c1 +Cc1ccc(CNC(=O)C2CC(=O)N(Cc3ccco3)C2)cn1 +Cc1cccc(CNCC(C)(C)N2CCOCC2)c1C +CSc1ccc(CNC(=O)NCc2ccsc2)cc1 +O=C(Cc1ccc(Cl)cc1)Nc1cnc(N2CCOCC2)nc1 +CC(=O)c1ccc(S(=O)(=O)CC(=O)N2CCOCC2)cc1 +CC(C)CCNC(=O)C1CCN(C(=O)c2cc(C(C)C)no2)CC1 +Cc1nc(C(C)C)[nH]c(=O)c1C(=O)N1CCCCCC1 +CC(=O)Nc1cccc(C(=O)OCC(=O)c2ccc3c(c2)CCC3)c1 +Cc1ccc(C(=O)N(C)C2CCCN(c3ccccc3)C2)cc1 +O=C(COC(=O)C1CCCN1C(=O)C1CC1)NC1CCCCC1 +CCc1nnc(NC(=O)NC(C)Cc2ccc(O)cc2)s1 +COc1ccc(OC)c(CN(C)C(=O)c2ccc3ccccc3n2)c1 +CCS(=O)(=O)N1CCC2(CC1)CN(c1ccsc1)C(=O)CO2 +CC(C)(CO)Nc1ccc(NC(=O)c2ccc(F)c(F)c2F)cn1 +CCc1nc(Cn2nc(C)c(C)c(C#N)c2=O)cs1 +CCC(=O)c1ccc(OCC(=O)Nc2cc(C)on2)cc1 +Cn1ccnc1Cn1ccnc1-c1cc(F)cc(Br)c1 +Nc1c(-n2ccnc2)ncnc1-n1nnc2ccccc21 +CCCS(=O)(=O)Nc1cccc(-c2ccc(OC)nn2)c1 +CC(C)C(=O)Nc1ccc(NC(=O)Nc2ccccc2)cc1 +CC(NC(=O)Nc1ccccc1OCCC(N)=O)c1ccncc1 +CSc1ccc(OC2CC2)c(S(N)(=O)=O)n1 +CC(=O)NC(C)(C)c1noc(-c2cn(-c3ccccc3)nc2C)n1 +CCOC(=O)C1(C)Oc2cc(NC(=O)CC)ccc2NC1=O +COCc1c(C(=O)NC2c3ccccc3-c3ccccc32)noc1C +CCN(C(=O)CSc1ncnc2sc3c(c12)CCC3)C1CC1 +CCNC(=O)Cn1ccc(NC(=O)C(C)(C)c2cccc(F)c2)n1 +CN(C)c1cccc(NC(=O)C(C)(C)c2ccc(N)cc2)c1 +Cc1nc(C(=O)c2ccc(F)cc2)n2ccccc12 +COc1ccc(NC(=O)COC(=O)c2ccsc2)c(OC)c1 +CNC(=O)Cn1nc(C)c2cnn(-c3ccccc3C)c2c1=O +O=S(=O)(NCCOCC(F)(F)F)c1ccc2c(c1)CCCC2 +CN(CC(=O)N1CCC(C(O)c2ccccc2)CC1)c1cnccn1 +Cc1cccc(CNC(=O)CCc2nc3c(C)cccc3c(=O)n2C)c1 +Cc1cc(=O)c(C(=O)NCC(C)(C)Cc2cccc(Cl)c2)c[nH]1 +Cc1cnc2n(c1=O)CC(C(=O)N1CCC(O)CC1)CS2 +O=C(C1CC1(Cl)Cl)N(Cc1ccco1)Cc1cccs1 +CC(Cc1ccccc1Br)NC(=O)Cc1cccnc1 +CC(NCC(N)=O)c1ccc(S(=O)(=O)N(C)C)cc1 +CCCNc1nc2c(c(=O)n(C)c(=O)n2C)n1C +Cc1cccc(NC(=O)N2CCOCC2C2CC2)c1C +Cc1n[nH]c(SCC(=O)Nc2nc3ccccc3s2)n1 +CCN(C(=O)c1ccc(OC)nn1)C1CCN(c2ccccc2)C1=O +CC(NC(=O)N(C)Cc1cccc(OC(F)F)c1)c1nncn1C +C#CCNC(=O)c1ccc(=O)n(CCCc2ccc(Cl)cc2)c1 +Cc1ccc(=O)n(CCCCC(=O)Nc2cccc(N)c2)c1 +CC(NC(=O)c1ccncc1)c1nc2ccccc2n1C +COc1cccc(OC)c1C(=O)N(C)CC(N)=O +Cc1ccc(F)cc1NC(=O)CSc1nn2cnnc2s1 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccc(-n3cccc3)cc2)cc1 +Cc1ccc(S(=O)(=O)c2c(C)c(C)n(CC(C)C)c2N)cc1 +CCCCNC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1 +COC(=O)c1cc(CNC(=O)NC(C)c2ccncc2)oc1C +COc1ccc2cc(C(=O)NCCCN3CCCC3=O)[nH]c2c1 +Cc1ccc(N)cc1NC(=O)COc1cccc(C)c1C +Cc1ccc(NC(=O)CN2C(=O)CCSc3ccccc32)c(C)c1 +O=C(NCCCSc1ccccc1)Nc1nccs1 +Cc1n[nH]c(-c2cccc(CNC(=O)CCCn3cccc3)c2)n1 +Cc1nnc(SCC(=O)Nc2sccc2C#N)n1C(C)C +CCc1nnc(NC(=O)CCn2ncc(=O)c3ccccc32)s1 +CC(C)CN1C(=O)CCc2cc(NC(=O)C(C)(C)C)ccc21 +CC(=O)c1ccccc1NC(=O)c1cccc(S(C)(=O)=O)c1 +O=C(Nc1ccncc1)c1cnc(C2CCCO2)s1 +COc1ccccc1OCC(C)(O)c1ccccc1 +CC1=NC(C(F)(F)F)(C(F)(F)F)N=C(N(C)C)O1 +COC(=O)c1ccc(OCC(=O)Nc2nccs2)cc1 +Cc1cc(F)ccc1CCNCc1ccc(S(C)=O)cc1 +O=C1CC(c2ccc(Cl)cc2)Cc2nc3ncnn3cc21 +C#CCNC(=O)c1ccc(NC(=O)OC(C)(C)C)cc1O +COc1ccccc1C(=O)NC(C)(C)c1nc(C)c(C)s1 +N#Cc1nc(C=Cc2ccc(F)cc2)oc1NCc1cccnc1 +Cc1ccc(NC(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)cc1 +COCCC(C)NC(=O)N1CCCN(C(=O)Oc2ccccc2)CC1 +O=C(Nc1ccc(-c2nccs2)cc1)C1CCC1 +O=C(NCC(O)c1ccco1)Nc1ccc(Oc2cccnc2)nc1 +CC(C)n1nc(O)c2c(-c3cccs3)c3c(nc21)[nH]c(=O)n3C +COc1ccc(SC(C)C(=O)N2CCNCC2)c(C)c1 +O=C(Nc1cc(Cl)cc(Cl)c1)c1ncccc1O +CCCC1CN(C(=O)c2ccnc(OCc3ccccc3)c2)CCO1 +CCOc1ncccc1C(=O)Nc1ccc(N2CCCCC2)nc1 +CN(CCc1ccccc1)C(=O)c1ccc(Cn2cc(Cl)cn2)o1 +COc1ccc(-n2nnc(CO)c2C(C)C)cc1OC +c1cnc2c(-c3cc(N4CCOCC4)ncn3)cccc2c1 +COc1cc(C(=O)NCCc2nc(C)ncc2-c2ccncc2)ccn1 +N#Cc1cccc(OCC(=O)N2CCN(Cc3ccccc3)CC2)c1 +O=C(NC1CCN(c2nccs2)CC1)c1ccc(F)cc1 +O=C(NC1COc2ccccc2C1)N1CCCCC1c1cn[nH]c1 +Cc1ccc(C(O)CN2CCN(c3ccccc3F)CC2)cc1N +COc1cc(C(=O)NCCc2nc(C)c(C)s2)ccn1 +O=C(c1ccc(F)cc1F)N(Cc1cnc2ccccn12)C1CC1 +Cn1cc(C(=O)N2CCCC2c2ccc(C(C)(C)C)cc2)ccc1=O +Fc1cccc2ncnc(N3CCc4sccc4C3)c12 +CCC1CCCN(C(=O)c2ccc(Cl)cc2)C1 +COc1ccc(CN2CC(c3nc(C(C)(C)OC)no3)CC2=O)cc1 +CC(=O)Nc1nc(C(=O)NCCOc2ccccc2F)cs1 +CC(=O)NCC(=O)NC(C)c1cccc2ccccc12 +CN(CCc1ccccn1)C(=O)C1COc2ccc(F)cc2C1 +CCOc1ccc(Cl)c(C(=O)NCC(=O)NC)n1 +COCCNC(=O)c1ccc(-c2nc(-c3cccc(F)c3)no2)cc1 +Nc1ccc(Cl)c(C(=O)N2CCN(c3ncccn3)CC2)c1 +O=C(CCNC(=O)c1cccs1)OCC(F)F +Cc1nc2cc(=O)[nH]n2c(C)c1CC(=O)Nc1nccn(C)c1=O +CCCc1nc2cc3c(cc2n1CC(C)C#N)OCCO3 +CCCC(=O)N1CCCC1C(=O)NCc1ccc(OC)c(F)c1 +O=C(Nc1ccc(F)cc1F)c1ccc(Cn2cc(Cl)cn2)o1 +Cc1ccccc1C1CC1C(=O)NCCc1n[nH]c(-c2ccco2)n1 +CCC(C)CS(=O)(=O)NC1CCN(c2c(F)cccc2F)C1=O +Cc1ccc(OC(C)C(=O)N2CCOCC2)c(C)c1 +CC(C(=O)N1CCC(C(N)=O)CC1)S(=O)(=O)c1ccccc1F +O=C(CNC(=O)c1ccn2ccsc12)NC1CCCCC1 +O=C(CCc1ccco1)NCc1ccc2c(c1)OCCO2 +CCN1CCN(C(=O)c2cc(N)c[nH]c2=O)CC1 +Cc1ccc(Cc2nnc(NC(=O)c3ccc(F)cc3)o2)cc1C +C#CCNC(=O)CN1CCN(S(=O)(=O)CCC)CC1 +Cc1ccc(S(N)(=O)=O)cc1NC(=O)c1cccc2ccccc12 +Cc1cc(C)n2nc(SCc3nc4ccccc4nc3C)nc2n1 +O=C(NCCOc1ccc2c(c1)OCO2)c1ccc(F)c(F)c1 +N#CCCN(CCC#N)C(=O)c1ccc(N2CCCC2=O)cc1 +CC(=O)Nc1cccc(Cn2ccc(C)c(C#N)c2=O)c1 +CCNC(=O)c1ccc(NC(=O)c2ccc(C)cc2)cc1 +C=CCN(CCO)S(=O)(=O)Cc1noc2ccccc12 +CCC(NC(=O)NCc1scnc1C)c1ccc(F)cc1F +CC(C)(C)c1ccc(C(=O)OCC(=O)N2CCOCC2)cc1 +CCn1c(=O)n(Cc2ccco2)c(=O)c2c3c(sc21)CCCC3 +CC(C)c1ccc(NC(=O)C2C(=O)COC2=O)cc1 +COC(=O)Nc1ccc(NC(C)C(=O)NCc2ccccc2)cc1 +COc1ncccc1CN1CC(=O)N(C)c2ccccc2C1=O +Cn1cccc1C(=O)N1CCn2c(CN3CCCC3=O)nnc2C1 +Cc1c(Br)cccc1CNc1ccc(C(N)=O)cc1 +Cc1ccc2c(c1)nc1n2C(CNCc2nccs2)COC1 +Cc1cc(C)c(CNC(=O)c2ccc(F)nc2)c(C)c1 +CCOC(=O)c1cnoc1-c1ccc(Br)cc1 +Cc1ccc(OCc2nnc(NC(=O)NCc3ccoc3)s2)cc1 +CCC(Sc1nccn1C)C(=O)Nc1ccc(Cl)cn1 +CCOC(=O)Cc1cc(=O)n(-c2nc3ccccc3s2)[nH]1 +CC1Oc2ccccc2N(CCC(=O)N(C)c2ccccn2)C1=O +CC(C)c1cc(=O)n(CC(=O)Nc2cc(Cl)cc(Cl)c2)cn1 +COc1ccccc1OCc1nc(C(=O)N2CCCC2)cs1 +CC(C)n1nccc1NC(=O)c1ccc2ccccc2c1 +O=C(NCc1ccccc1Cl)NC1COc2ccccc2C1 +O=C(NCCS(=O)c1ccccc1)c1cc(-c2ccccc2)no1 +COCC(C)N1CCN(C(=O)C(C)NC(C)=O)CC1 +CNC(=O)c1csc(NC(=O)Nc2ccc(C)cc2)n1 +Cc1ccc2c(c1)C(c1ccc(F)cc1)NCC(=O)N2 +CCc1nn(C)c(OC)c1CN(C)C(C)Cc1ccc(O)cc1 +COCCNC(=O)CCNC(=O)Nc1ccc(Br)cc1 +Cc1ccc(CCC(=O)Nc2cc(CO)ccn2)cc1 +CC(C)n1cnc(-c2ccccc2Br)c1 +CCc1ccc(C(NCC(=O)N2CCOCC2)C(C)C)cc1 +N#Cc1ccc2nc(-c3cncc(Br)c3)nn2c1 +Cc1cc(C)n2nc(C)c(C(=O)Nc3cc(C(C)C)n[nH]3)c2n1 +CN(C)c1ncnc2c1CCN(C(=O)c1ccc3[nH]ccc3c1)CC2 +O=C(NC1CCN(C(=O)c2ccncc2)C1)c1ccc(F)c(F)c1F +CCS(=O)(=O)Nc1ccn(Cc2cccc(F)c2)n1 +CC(C)(CNc1cn[nH]c(=O)c1Cl)c1cccc(Cl)c1 +CCn1nccc1CNc1cc2c(cc1F)NC(=O)CC2 +CCOC1CC1C(=O)N1CCCC1c1noc(C2CC2)n1 +CCOCC1CCCN(C(=O)NCC(=O)NC(C)(C)C)C1 +O=C(Cc1ccc2c(c1)CCO2)NCC(=O)Nc1ccc(Cl)cc1 +CCn1c(C(=O)NCc2ccc(OC)c(OC)c2)cc2sccc21 +O=S(=O)(c1cccc(F)c1)N1CCN(Cc2ccccc2)CC1 +Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCC3)c(Cl)c1 +CCC(=O)Nc1nc(C)c(-c2nc(-c3ccccc3)no2)s1 +Cc1cc(C)n(CC2CCCN2C(=O)c2c(C)noc2C)n1 +O=C(COC(=O)C1C2CC3OC(=O)C1C3C2)Nc1ccccc1 +CC1CCCCN1S(=O)(=O)c1ccc2c(c1)NC(=O)CC(=O)N2 +CC1(C)COc2ccc(NC(=O)c3c(F)cccc3F)cc2NC1=O +Cn1c(=O)n(CC(O)COc2ccccc2F)c2ccccc21 +Cc1ccc(N2CC(C(=O)Nc3ccccn3)CC2=O)cc1Cl +CCCCS(=O)(=O)N1CCCC1C(=O)NC1CCCCCC1 +N#Cc1nnc2ccccc2c1NCc1ccccn1 +NC(=O)NCc1ccc(NC(=O)COc2ccccc2F)cc1 +Cn1c(=O)n(CC(=O)NC2C3CCOC3C2(C)C)c2ccccc21 +COc1ccccc1OCC(=O)NCc1cccc(C(F)(F)F)c1 +COCCCNC(=O)c1cc(-c2ccc(Cl)cc2)n[nH]1 +O=C(NCc1ccncc1)c1cc(Cl)ccc1Cl +Cc1nc(C)n(CC(=O)N2CCOC(c3ccc(F)cc3)C2)n1 +Cc1ccc2ncc(C(=O)NCc3noc(C)n3)n2c1 +CCC1CN(C(=O)Nc2cccnc2OC)CCO1 +CC(C)C(=O)OCc1cc(=O)n2nc(C3CC3)sc2n1 +CC(C)Oc1cccc(-c2nc(-c3cccnc3)no2)c1 +Cc1sc2nc(NCC3CCCO3)n3ncnc3c2c1C +CC1Cc2cc(C(=O)N3CCCC3)ccc2N1S(C)(=O)=O +N#CCC1CCCc2c1cnn2CCCc1ccccc1 +Cc1cnc(C(=O)N(C)Cc2sccc2C)cn1 +Nc1cccc(OCCNC(=O)C2CCCCC2)c1 +N#Cc1ccc(CCC(=O)NCc2ccoc2)cc1 +Cn1c(SCC(=O)C(C)(C)C)nc2ccccc21 +COc1cc(O)ccc1CNc1cc(F)ccc1F +O=C(COc1cccnc1)NC1CCC(n2cnnc2)CC1 +CCOc1ccc(F)c(C(=O)NC(C)c2ncc(C)s2)c1F +O=C(Nc1c[nH]c2ccccc12)c1cnc(N2CCOCC2)nc1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(N(C)C)nc1 +COC(=O)Cn1cc(NC(=O)c2cnoc2C)cn1 +COCC(C)NC(=O)Nc1ccc(C(=O)NC(C)C)c(C)c1 +Fc1cccc(CN2CCc3nc(N4CCOCC4)ncc3C2)c1F +N#Cc1cc(NC(=O)NC2CCN(c3ccccc3)CC2)ccc1F +O=C(NCCn1ccnc1-c1ncccn1)NC1CCCCCC1 +CNC(=O)CSc1nnnn1-c1ccc(OC)cc1 +COc1ccc(OCC(=O)N(C)CCC(F)(F)F)cc1 +CC(=O)c1cc(C(=O)NCC2(c3ccc(F)cc3)CC2)n(C)c1 +Cc1cccc(-c2nc3c(cnn3CC3CC=CCC3)[nH]2)n1 +O=C(Cc1ccc(Cl)cc1)NCc1nccc(N2CCOCC2)n1 +NC(=O)c1cnc(NC2CCCN(c3ncccn3)C2)c(Cl)c1 +CCC(C)NC(=O)NCCn1c(C(F)(F)F)nc2ccccc21 +CCOC(=O)N1CCCC(C(=O)OCCc2ccccc2)C1 +COc1ccc(C2(C(=O)N3CCN(CC(C)O)CC3)CCCC2)cc1 +O=C1COC2(COCCN(C(=O)c3cccnc3)C2)CN1CC1CC1 +Cc1nnccc1C(=O)N1CCN(c2ccc(F)cc2)CC1 +CCc1cccc(C)c1NCC(=O)c1cccc(N)c1 +CCOCCNC(=O)Cn1cnc2c(cnn2C)c1=O +Cc1nc(COC(=O)c2cccc3c2ccn3C)no1 +O=C(CCCNC(=O)c1ccco1)NCc1ccc(Cl)cc1 +CC(C(=O)N1CCC(OCc2ccccc2F)CC1)C1CC1 +O=C(CO)N1CCC2(CC1)COCCN(c1nccs1)C2 +O=C(CNS(=O)(=O)c1ccc(F)cc1Cl)NCc1ccco1 +CCCN(CCO)C(=O)Nc1cccc(OC)c1 +COCCOc1ccc(C(=O)Nc2ccc(N(C)C(C)=O)cc2)cc1 +CCSc1nnc(NC(=O)c2ccc(C)o2)s1 +CC1(C)CCC(NC(=O)NC2CC2)c2ccccc21 +Cc1ccnc(NC(=O)c2cc(C(N)=O)cn2C)c1 +CC(=O)N1CCN(C(=O)c2cc3cccc(C)c3o2)C(C)(C)C1 +CCCCC(COC)NC(=O)c1c[nH]c2cccc(F)c12 +CN(C)C(=O)c1cc(Br)cc(Br)c1Cl +CCS(=O)(=O)c1ccc(C2NCCNC2=O)cc1 +Cc1ccc(C(=O)Nc2c(C)cccc2C(C)C)o1 +CN(CCOc1ccccc1)C(=O)c1cc(=O)c2ccccc2o1 +CC(C(=O)NCc1ccccc1F)n1sc2ccccc2c1=O +COc1ccc(CN(C)c2nnnn2-c2ccccc2)cc1 +COC(=O)C1CCN(C(=O)CCc2nc(C)no2)c2ccccc21 +Cc1cc(N)ccc1NC(=O)CCCOC1CCCCC1 +N#Cc1ccccc1OCC(=O)NCCOc1ccccc1F +CCOc1ccccc1NC(=O)Cc1ccc2c(c1)OCCO2 +CCOCCC(=O)N1CCC(Nc2ccccc2OC)CC1 +CC(C)(C)OC(=O)N1CC(=O)c2ccc(Br)cc21 +CC(=O)Nc1nc(C(=O)N2CC(C)c3ccccc32)cs1 +COc1ccc(-c2nnc(NC(=O)c3ccco3)o2)cc1OC +COC(=O)c1cc(-c2sc(-c3ccncc3)nc2C)n[nH]1 +CN1C(=O)CN(C(=O)c2cccnc2OCC(F)F)c2ccccc21 +Cc1ccc(O)c2c1C(c1ccncc1F)NCC2 +N#Cc1ccc(C(=O)OCC(=O)C2=NC=CC2)cc1 +Cc1nc(C)n(CC(=O)N2CCC(Oc3cccc(F)c3)CC2)n1 +Cc1cccc(NC(=O)C(C)Oc2cccc(C(=O)NCCO)c2)c1 +COc1cc(C(=O)Nc2nccs2)c(-n2cccc2)cc1OC +O=C(COc1cccnc1F)Nc1ccc(C(F)(F)F)cc1 +COc1ccc(C2CC(=O)c3cnc(NC(C)=O)nc3C2)cc1OC +COCCCNC(=O)CN(C)C(=O)c1ccc(C)s1 +O=C(NCCNC(=O)C1CCC(F)(F)CC1)c1ccc(O)cc1 +COc1ccccc1NC(=O)Cn1[nH]c(-c2ccc(F)cc2)cc1=O +CCCCN(C)C(=O)c1cc2ccccc2oc1=O +Cc1ccc(-c2nnc(COC(=O)c3cccs3)o2)cc1 +COc1ccc2c(=O)cc(-c3cccc(N)c3)oc2c1 +CN(C(=O)CN(c1cccc(F)c1)S(C)(=O)=O)c1ccccc1 +CC(C)N(Cc1ccc(Cl)c(Cl)c1)S(=O)(=O)N(C)C +CCN(Cc1cccc(Cl)c1)C(=O)NCCCn1cccn1 +CCCCS(=O)(=O)NCc1c(C)nn(C)c1C +CC(C)N(C)C(=O)CN(C)C1=NS(=O)(=O)c2ccccc21 +CC(C)(C)OC(=O)N1CCCC(COc2cnccn2)C1 +Cc1cc(F)ccc1NC(=O)c1c[nH]nc1-c1ccccc1F +COC(=O)C1CCCCC1NC(=O)c1ccon1 +O=C1CCOc2cc(OCc3ccccc3)ccc21 +COCC(=O)Nc1ccc(-c2nc(Cn3cc(C)cn3)c(C)o2)cc1 +COC(=O)C(CNC(=O)OC(C)(C)C)C(C)(C)O +Cc1cc(C(=O)NCCCS(N)(=O)=O)cc(C)c1OC(F)F +O=C(NCC1CN2CCCCC2CO1)C1CCC2CCCCC2C1 +CCC(=O)Nc1ccc(C(=O)CSc2ncc3ccccn23)cc1 +CCc1noc(CC)c1CC(=O)Nc1ccc2c(c1)NC(=O)C(C)O2 +O=C(COc1ccc(Cl)cc1Cl)NCCc1ccco1 +CC(C)CNC(=O)C1CNCc2cc(Cl)ccc21 +CCc1ccc(NC(=O)COc2cccc(C#N)c2)cc1 +C=CCNC(=O)CSc1nnc(-c2cccs2)o1 +OC(CNCc1ccccn1)c1cccc(Br)c1 +Nc1nnc(SCC(=O)Nc2cccc3ccccc23)n1C1CC1 +Cc1cc(C#N)nn1Cc1cccc(Br)c1 +Cc1nc(NCCSc2cnn[nH]2)c2cccnc2n1 +C=CCn1c(SC2CCN(C)C2=O)nnc1-c1ccoc1C +Cc1ccc(C(=O)Nc2cnc3sc(C(C)C)nn3c2=O)cc1 +COc1ccc(CC(C)C(=O)NC(C)(C)C#N)cc1OC +CC(C)CNC(=O)c1ccccc1CN1CCOCC1 +CCCNS(=O)(=O)c1cc(C(C)C)ccc1OC +CC1CN(C(=O)CN2CCN(c3ccc(O)cc3)CC2)CC(C)O1 +CC(C)c1nc(CNC(=O)c2ccc(-c3cccnc3)nc2)no1 +Cc1nc(C)c(CC(=O)N(C)Cc2cc(C)on2)c(=O)[nH]1 +Nc1cc(Cl)ccc1N1CCN(CCO)CC1 +NC(=O)CC(NC(=O)c1cccc(-c2ccoc2)c1)C1CCOCC1 +CCCOc1ccc(CNC(=O)NCc2cscn2)cc1 +O=C(COC(=O)c1ccc(O)cc1O)Nc1ccc(Cl)cn1 +CCCCn1nnc(S(=O)(=O)c2ccc(C)cc2)c1N +CS(=O)c1ccc(CNc2cccc(C#N)c2)cc1 +O=S(=O)(Nc1ccccn1)c1ccc2c(c1)OCCO2 +CN1CCc2ccc(NCc3ccn(-c4ccccc4)n3)cc2C1=O +COC1CCC(CC(=O)NCC2(c3ccc(F)cc3F)CC2)CC1 +Cc1nc2ccc(NC(=O)NCCCC(N)=O)cc2s1 +CCCN(C)C(=O)Nc1ccc(C(=O)NCc2ccc(F)cc2)cc1 +CC(=O)NCCNC(=O)NCc1sccc1C +CN(C)C(CNCc1ccc(-n2ccnc2)cc1)c1ccccc1 +CC(C)NC(=O)N1CCN(CCc2ccccc2)CC1 +O=C(Cc1ccc(N2CCCC2=O)cc1)Nc1ccccc1 +CC(CCC(C)(C)C)NC(=O)Nc1ccc(C(N)=O)c(F)c1 +CC1(C(=O)NCCO)Oc2ccc(Cl)cc2NC1=O +CCNC(=O)CN(C)S(=O)(=O)c1cc(Br)ccc1C +CC(=O)N1CCc2nc(NC(=O)c3cccs3)sc2C1 +Cc1noc(C)c1CN(C)C(=O)C1(c2ccc(Cl)cc2)CCC1 +O=C(NCc1ccoc1)C1(c2cccc(Cl)c2)CCC1 +CCOCCCNc1ncnc2sc3c(c12)CCC3 +COC(=O)CNC(=O)COc1ccc2c(C)cc(=O)oc2c1 +Cc1ccc(CNC(=O)NC(C)c2ccc3c(c2)OCCO3)cc1 +O=C(Nc1c(O)c(Cl)cc(Cl)c1Cl)c1cc[nH]c(=O)c1 +O=C(C1CCC1)N1CCC(Nc2cccnn2)CC1 +Cc1nc(C)c(CNCc2ccccc2-n2cccn2)s1 +Cc1ccc2c(c1)CCCN2CC(=O)N1CCCC(C)C1 +CCNC(=O)c1cccc(NC(=O)c2ccc3c(c2)OCCCO3)c1 +CNC(=O)c1cccc(CNc2ccc(F)cc2Cl)c1 +O=C(Cn1cnnn1)N(Cc1ccccn1)CC1CCCO1 +COCCCN(C)C(=O)Nc1ccccc1Cn1cccn1 +CCCCNC(=O)C(C)S(=O)(=O)c1ccccc1Br +NS(=O)(=O)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +CCc1onc(C)c1NC(=O)N1CCN(C(=O)COC)CC1 +COC(C)(C)c1noc(-c2cc(C(C)C)n(C(C)(C)C)n2)n1 +CC(C)c1ccc(NC(=O)NCC(=O)N2CCCCC2)cc1 +CSc1ccc(C(=O)Nc2ccccc2-n2ccnc2)cc1 +Cn1cc(C(=O)NCc2cscn2)c(-c2ccc(F)cc2F)n1 +COc1ccccc1OC(C)CNC(=O)c1scnc1C1CC1 +CNC(=O)c1ccc(-c2ccccc2OC(C)C)nc1N +Cc1cccc(C)c1OCC(=O)N1CCCC(n2cncn2)C1 +CCCC(=O)N1CCC(Cn2ccc3cccnc32)CC1 +Cc1cncc(C(=O)Nc2ccc(NC(=O)c3ccc(C)o3)cc2)c1 +Cc1ccc(OCC2NCCc3cc(O)ccc32)cc1 +CSc1ncc(C(=O)N(C)C)cc1OC1CC1 +Cn1cc(CN2CCOC3C(OCC4CC4)CCC32)cn1 +CCCNC(=O)CN(C)C(=O)c1cc(OC)ccc1Br +COc1ccc(Cl)cc1NC(=O)Nc1ccc2c(c1)OCCO2 +O=C(CCc1nnc2ccccn2c1=O)NCCc1ccco1 +COCCN(Cc1ccccc1)C(=O)Nc1ccccc1OC +N#CCn1ccc(NC(=O)c2ccccc2Br)n1 +CCOc1ccc(Br)cc1NC(=O)NC(C)CCCO +CCc1csc(CNc2ccc3cc[nH]c3n2)n1 +CCC(CC)n1ncc(C(=O)N2CCN(CCOC)C(=O)C2)c1C +COC(=O)CSc1nc(N2CCCC2)c2c(c1C#N)CCCC2 +Cc1cc(C)cc(OCn2ccc(C(=O)NC3CC3)n2)c1 +O=C(NC1CCCNC1=O)c1ccc(Br)cc1 +COc1ccccc1OCc1nnc2c(N)cccn12 +CCc1nc(CCNC(=O)CNC(=O)NC)sc1C +COc1ccc(OCCNS(=O)(=O)c2ccc3c(c2)CCO3)cc1 +Cc1csc(=O)n1Cc1nc(-c2ccc(C#N)cn2)no1 +COc1ccc(C)c(NC(=O)NC(CO)c2ccccc2)c1 +CC(C)(C)C(=O)Nc1ccc(N2CCCCC2)nc1 +CC1CN(C(=O)CNC(=O)COc2ccccc2)CCO1 +CCOc1ccc(Cn2nc(C3CC3)cc(C(F)(F)F)c2=O)nc1 +O=C(OC1CN(c2nc3ccc(F)cc3s2)C1)c1cnccn1 +O=C(Cc1cc2ccccc2[nH]c1=O)OC1CCCCC1 +CC(=O)c1ccccc1NC(=O)c1cnn(C)c1-n1c(C)ccc1C +CC1CCN(S(=O)(=O)N2CCOc3ccccc32)CC1 +Fc1cccc2c1CCC2Nc1ccc2nnnn2n1 +CCC(CC)NC(=O)NCc1ccc(F)c(C)c1 +CCNC(=O)NC1(C(=O)NCC2CC2C)CCCC1 +CN1CCN(C(=O)c2cncc(Br)c2)CC1 +CC(C)Cc1nnc(NC(=O)N2CCCC(C)C2)s1 +Cn1cc(CCC(=O)NCC(O)c2ccccc2)cn1 +Cc1cn(S(=O)(=O)c2ccc(Cl)c(C)c2Cl)cn1 +Cc1ccn2ncc(C(=O)OC(C)c3nc(C)no3)c2n1 +COc1cc(C(C)Nc2ncc(C#N)cc2Cl)ccc1OCCO +CN(C)C(=O)C1CCN(C(=O)Nc2ccc(Cl)c(Cl)c2)CC1 +COc1ccc(C(=O)N(C)C(C#N)c2ccccc2)cc1OC +CCOC(=O)C1CCN(C(=O)Cc2cc(-c3ccccc3)on2)CC1 +CNC(=O)c1ccc(CNC(=O)Cn2ccc3ccccc32)cc1 +CS(=O)(=O)NCC1CCCCN1C(=O)CCn1cccn1 +O=C(NCC1CCCO1)c1csc(-c2cc3ccccc3[nH]2)n1 +CCCNC(=O)Cn1c(=O)ccc2cc(N)ccc21 +CCn1nc(C(C)C)cc(C(N)c2ccc(F)cc2)c1=O +COCCNC(=O)c1ccccc1NC(=O)Nc1cccc(Cl)c1 +CC(=O)Nc1ccc(C)c(NC(=O)NC2CCCCCC2)c1 +CCOc1ncc(C(=O)Nc2c(C)n[nH]c2C)cc1Cl +CNC(=O)c1ccccc1C#CCNC(=O)c1cccc(C)c1 +CCC1CN(CC(=O)OC(C)C)c2cc(C(C)=O)ccc2O1 +Cc1cc(C)c(C#N)c(SCC(=O)N2CCCC(C)C2)n1 +CN(Cc1cnn(C)c1)S(=O)(=O)c1ccc(F)cc1F +O=S(=O)(NCc1ccccc1)Nc1cccc(-c2ccccn2)c1 +CC1CCCN(C(=O)C2C3CC4OC(=O)C2C4C3)C1 +CC1(COC(=O)CCn2nnc3ccccc3c2=O)COC1 +CCc1cccc(C)c1NC(=O)c1ccc(F)c(F)c1 +Cn1cc(S(=O)(=O)Nc2ccc3oc(=O)[nH]c3c2)cc1C(N)=O +CCOC(=O)CCC(=O)Nc1nnc(-c2csc(C)n2)o1 +CCc1cc(N)c2onc(CC(=O)NCCO)c2c1 +COCCN1CCN(C(=O)Nc2cnn(CC(F)(F)F)c2)CC1=O +COc1ccc(C(=O)N(C)Cc2ccccc2)nn1 +O=C(OCc1ccccn1)C1(c2ccc(Cl)cc2)CC1 +Cc1cc(C2CN(Cc3cccc(O)c3)CCO2)ccc1F +N#CCOc1cccc(CC(=O)Nc2cc(F)c(F)cc2F)c1 +CCSc1cc(C(=O)NCc2ccc(C)nc2)ccn1 +CC(C)C(=O)NCCCSc1ccc(F)cc1 +CC12CCC(CC1C(=O)NC1CC1)C1(C2)NC(=O)c2ccccc2N1 +N#CCCCS(=O)(=O)NC(c1ccccc1)C1CCCC1 +COc1ccccc1NC(=O)CSc1ccccc1 +CCC(NC(=O)c1ccc2c(c1)OCC(=O)N2)c1cc(F)ccc1F +CN1CC(=O)N2CCN(C(=O)c3ccccc3Cl)CC2C1=O +Cc1cc(Cl)ccc1NC(=O)NC(C)C(=O)NCc1ccccc1 +CNC(=O)NCC(C)(c1ccccc1)c1ccccc1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(C#N)cc1 +CCCS(=O)(=O)c1ccc(C)cc1C(=O)OC(C)C +CC(=O)Nc1cc(C(=O)NCc2nc3ccccc3n2C)ccc1F +Cc1ccc(OCC(=O)Nc2ccc(C(=O)N(C)C)cc2)cn1 +CC(CNC(=O)CCc1ccsc1)Oc1ccccc1 +Cn1nnc2c(Nc3ccc(F)c(F)c3)ncnc21 +CN(C)c1nc2ccc(NC(=O)c3scnc3C3CC3)cc2o1 +COc1cccc(-c2nc3cc(Cl)ccn3c2CO)c1 +Cc1csc(NC(=O)c2ccc(C(C)C)nc2N)n1 +COc1cc(C2NCCc3c2ccc(C)c3F)ccc1O +CCOC(=O)CN(C(=O)c1cc(C)no1)C(C)C +N#Cc1cnn(Cc2ccccc2)c1C(F)(F)F +CC(C)S(=O)(=O)N(Cc1ccon1)c1ccccc1F +C=CCN1C(=O)NC2C1N(S(C)(=O)=O)CCN2S(C)(=O)=O +O=C(OCC1CC(=O)N(Cc2ccccc2)C1)c1cnc2ccccn12 +CCC(=O)c1ccc2c(c1)N(Cc1c(C)noc1C)C(=O)C(C)(C)O2 +CCN(Cc1ccccc1C)C(=O)CCn1cncn1 +Cc1cnc(CNC(=O)N(C)CCN(C)C(=O)OC(C)(C)C)s1 +CCCn1nc(C)c(C(=O)N2CC(CO)OCC2C)c1C +Cc1cc(C)n(CC2CN(Cc3noc(C)n3)CCO2)n1 +COc1ccccc1N1CCN(C(=O)C2CC(=O)N(C3CC3)C2)CC1 +Cc1c(C#N)c(NC(=O)CN2CCOCC2C)n(C2CCCC2)c1C +CC1CCCN(C(=O)c2cc(S(=O)(=O)N(C)C)ccc2Cl)C1 +CC(C)CCC(=O)N(C)Cc1cc(C#CCO)cs1 +C#CCOC1C(O)C(CO)OC1n1ccc(N)nc1=O +N#Cc1ccc(C(=O)Nc2ccc(Br)cn2)c(F)c1 +Cc1ccc(C)c(SC(C(=O)N2CCNCC2)C(C)C)c1 +CCC1CN(Cc2ccc(C#N)cc2)CCC(=O)N1Cc1ccccc1 +CCc1cc(C#N)c(NC(=O)Cc2ccc(F)c(F)c2)s1 +O=C(Cc1ccc(N2CCCC2=O)cc1)OCC1CCCO1 +CCC(CC)C(=O)N1CCc2ccc(C(C)O)cc2C1 +CC(=O)Nc1ccc(NC(=O)NC(C)(C)c2cccc(F)c2)cc1 +Cc1ccc(NC(=O)c2cccc(Cn3cncn3)c2)cc1C +O=C(CN1C(=O)COc2ccc(Cl)cc21)Nc1ccccc1F +Cc1nc(COc2ccccc2N)n2ccccc12 +Cn1cc(S(=O)(=O)NC(CO)c2ccccc2F)cn1 +O=c1cnn(Cc2ccc(Cl)cc2)c2ccccc12 +COc1ccc(C(=O)OC(C)C(=O)Nc2ccccc2)cc1 +COC(=O)C1CCN(C(=O)C(C)Oc2ccccc2)c2ccccc21 +Cc1c(C(=O)Nc2nc[nH]n2)cnn1-c1ccc(Br)cc1 +CC(C)(C)c1ccnc(COc2cccc(N)c2)n1 +Cc1cc(C)n(C2CCCN(C(=O)c3ccc(C#N)c(C)n3)C2)n1 +CCOC(=O)CC(C)CNC(=O)N1CCCC1c1cccc(C)n1 +CCC(CC)NC(=O)NCc1cc(C(=O)OC)c(C)o1 +CC(O)CNC(=O)C1CSc2nccc(=O)n2C1 +CCOC(=O)C(Nc1ccc(F)cc1)c1ccsc1 +COc1ccc(OC)c(NC(=O)CCn2nc(C)cc2C)c1 +CCOC(=O)c1c(C)[nH]c(-c2csc(CC#N)n2)c1C +CCCNC(=O)CSc1ccc(NC(=O)C2CC2)nn1 +Cc1noc(C)c1CC(=O)Nc1cccc(-n2cn[nH]c2=O)c1 +Cc1nc(CN(C)S(=O)(=O)c2ccccc2C(F)(F)F)no1 +COCC(=O)NC(C)c1ccc(OC(F)(F)F)cc1 +Cc1cc(=O)c(OCC(=O)N=c2[nH]cc(C)s2)c[nH]1 +COc1ccccc1C(NC(=O)NCc1ncnn1C)C(C)(C)C +CCCN(CCO)S(=O)(=O)c1ccc2c(c1)OCO2 +CCn1nc(C#N)cc1-c1ccc(OC(C)C)cc1 +CNc1cc(-c2cccc(C(F)(F)F)n2)c2cc[nH]c2n1 +CC1C(=O)NCCN1S(=O)(=O)N1CCCC1c1ccco1 +Cc1noc(C2CN(C(=O)Cn3c(=O)oc4ccccc43)C2)n1 +c1ccc(-n2nc(-c3ccc4c(c3)OCO4)c3c2CCNC3)cc1 +O=C(CCc1ccccc1)Nc1nnc(C2=COCCO2)o1 +CN(C)c1ccc(C(F)(F)F)cc1NC(=O)c1ccco1 +CC1CCCN(C(=O)Nc2cccc(C(=O)NC(C)(C)C)c2)C1 +CCOc1cc(C)ccc1NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +CC(=O)N1CCC2(C1)c1ccccc1S(=O)(=O)N2C +CC(CC(O)c1ccco1)NC(=O)Nc1cnn(C(C)C)c1 +COC(=O)CSc1nc2ncc3c(n2n1)CCC3 +COc1ccc(C2(CNC(=O)c3cc(C)on3)CCCC2)cc1 +COCCNC(=O)c1ccc(Cl)c(NC(=O)CC2CCCC2)c1 +O=C(Cn1c2ccccc2c(=O)c2ccccc21)NCC1CC1 +CCN1CC(c2nc3ccccc3n2Cc2ccc(F)cc2)CC1=O +CC(C)n1cnnc1SCC(=O)N1CCCC1c1cccc(F)c1 +Cc1csc(C(C)NC(=O)Nc2ccc(-n3cccn3)c(F)c2)n1 +CCOc1ccc(C(=O)N=c2[nH]nc3ccccn23)cc1 +CN(Cc1cccc(O)c1)C(=O)c1cn(CC(=O)N2CCCC2)nn1 +O=C(CSc1ccc(-c2cccs2)nn1)NC1CC1 +COc1ccccc1-c1noc(C(C)NC(=O)C2CCCO2)n1 +COc1cc(OC)c(-c2ncnc(C)c2N)c(OC)c1 +Cc1ccnc(NC(=O)CN(C)c2ccc(C#N)cc2F)c1 +c1nc(NCc2ccc3c(c2)OCO3)c2sccc2n1 +CCOc1cccc2sc(-n3ncc(C#N)c3N)nc12 +CN(C)c1ccccc1NC(=O)NCCC(C)(C)C +Nc1cc2c(nn1)CCN(C(=O)C1CCc3ccccc31)C2 +CC(C)Sc1ncccc1C(=O)NCC1COCCO1 +CC(c1ccccc1)N(CC(N)=O)C(=O)c1ccc(-n2ccnn2)cc1 +O=C(NCc1ccsc1)c1ccc2c(c1)OCO2 +CC1CCN(C(=O)C2c3ccccc3CC(=O)N2C(C)C)CC1 +N#Cc1ccc(F)c(C(=O)Nc2cccc(F)c2)c1 +Cc1cc(NC(=O)CN(C)S(=O)(=O)c2ccc(C#N)cc2)no1 +Cc1nc(N(C)C)ncc1C(=O)NCc1csc(N2CCCC2)n1 +O=C(Cc1cccc(F)c1)NCC(c1ccccc1)N1CCOCC1 +CCc1nnc(SCc2cc(=O)n3oc(C)cc3n2)[nH]1 +COC(=O)c1ccc2c(c1)ncn2Cc1cccc(N)c1 +O=C(COC(=O)c1cccc(-n2cnnn2)c1)NC1CCCC1 +CC(=O)NCCNC(=O)c1ccc(Cn2ccnc2)cc1 +CC1Sc2ccc(C(=O)N(C)CCc3ccccc3)cc2NC1=O +Cc1cc(C)c(C(=O)N(CCO)Cc2ccccc2F)c(=O)[nH]1 +O=C(CCS(=O)(=O)c1cccc(Cl)c1)Nc1cccc(F)c1 +CCc1cccc(C)c1NC(=O)C(C)c1ccsc1 +CC(C)OCCC(=O)OC1CCCC1n1cccn1 +CCCCn1nc(C(=O)Nc2ccccc2C(C)=O)ccc1=O +CC(C)Oc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cc1 +O=C(NCC1(O)CCCC1)c1cc2ccccc2[nH]1 +O=S(=O)(NCc1cn2ccsc2n1)c1ccc2ccccc2c1 +O=C(NCc1cnn(-c2ccccc2)c1)C1CCCC1 +Cc1ccc(C)c(NC(=O)c2c(-c3cccnc3)noc2C)c1 +CC(CN1CCN(c2ccccc2)CC1)NC(=O)N1CCOCC1 +O=C1CCCN1c1ccc(-c2nc(Cc3ccccc3)no2)cc1 +COCCN1CCN(Cc2ccc(C(=O)NC(C)C)cc2)C(=O)C1=O +Cc1cc(C)n(CCNS(=O)(=O)c2ccc(C)s2)n1 +CCn1nc(C)c(NCc2ccc(OCc3noc(C)n3)cc2)c1C +O=C(Nc1cccc(CNc2nc3ccccc3o2)c1)c1ccncc1 +O=c1c2cccnc2ccn1CCCn1cnnn1 +O=C(OCC(=O)N1CCCC1)c1n[nH]c2ccccc12 +CCN(c1ccccc1)c1nc(N)nc2[nH]ncc12 +CC(C)CC(C(=O)Nc1nccs1)N1CCCCC1=O +CSc1nc(C)c(CCC(=O)Oc2ccccc2F)c(=O)[nH]1 +C#CCNC(=O)CCCCOc1cc(C)ccc1C +COc1cc(C)sc1C(=O)NC(C)c1ccc2c(c1)NC(=O)CO2 +COc1ccc(CN(C)C(=O)c2ccc(CNC(N)=O)cc2)cc1F +COCC(=O)N1CCC2(CC1)CNC(=O)c1ccc(OC)cc1O2 +O=C(COc1cccc(Cl)c1)NCCn1ncccc1=O +CC(C)Nc1nnc(SCC(=O)Nc2ccc(F)cc2)s1 +Cc1noc(C2CC3OCCC3N(Cc3cccc4ccccc34)C2)n1 +O=C(c1ccno1)N1CC2OCC(=O)N(c3ccccc3)C2C1 +CSc1nc(=O)[nH]c(C)c1C(=O)NCc1cn[nH]c1 +COc1ccccc1CNC(=O)Cn1c(N)nc(C)cc1=O +O=C(c1ccc(Br)cn1)N1CCSc2ccccc21 +CCCCc1ccc(NC(=O)NCCOC)cc1 +O=C(Cc1c(F)cccc1F)NCCC(=O)Nc1ccccc1 +Cc1nc(CN2CCN(CC(=O)NCCC(C)(C)C)CC2)cs1 +CNC(=O)c1ccc(C2CCCN2C(=O)c2cn[nH]n2)s1 +Cc1nn(C(=O)CCC(=O)NCc2ccccc2)c(C)c1CC(C)C +CCOC(=O)C1=C(C)C(C(=O)Nc2ccccc2)C(C)=N1 +COc1ccc(Cl)cc1C(=O)N1CCCC(CS(N)(=O)=O)C1 +CS(=O)(=O)c1cccc(NC(=O)c2cccs2)c1 +CCc1noc(CN(C)S(=O)(=O)Cc2noc3ccccc23)n1 +CN(C)C(=O)CCNS(=O)(=O)Cc1cccc(C#N)c1 +COc1ncccc1CNC(=O)Cc1ccsc1 +CC1CN(CCNc2cccc(Cl)c2)CCO1 +COc1ccc(S(=O)(=O)NCCc2ccccn2)c(C)c1 +c1ccc(-c2nnc(CNc3nccs3)o2)cc1 +COCCN1CCOCC12CCN(Cc1cccc(F)c1)CC2 +Cc1ccc(-c2nc3[nH]cnn3c2Nc2ccccc2)o1 +CC(C)(C)NC(=O)c1nn(-c2ccccc2F)c2c1CCC2 +CCc1nc(CNC(=O)Nc2nc(CC)n(C)n2)cs1 +Cc1cc(C(=O)NC2CCCc3c2cnn3C(C)(C)C)on1 +COc1cccc2c1OCC(NC(=O)Nc1cccnc1)C2 +O=C(CN1CCC(NC(=O)c2ccccc2)CC1)C1=NC=CC1 +CCNc1nc(C(F)(F)F)c(C(=O)OCC)o1 +COCc1nc(CN2C(=O)CCc3ccccc32)no1 +CC1(CNC(=O)Cc2ccc(F)c(F)c2)CCCC1 +COC1CCN(S(=O)(=O)c2cccc(F)c2)CC1 +CNC(=O)c1ccc(CNC(=O)c2ccoc2)cc1 +COc1cc(C)c(C(=O)N(CCC#N)Cc2ccco2)cc1OC +CCOc1ccc(CCC(=O)NCc2ccc(F)cc2)cc1N +COc1ccc(-c2c(CO)nnn2-c2ccc(OC)cc2)cc1 +C=CCNc1nnc(SC(C(N)=O)c2ccc(F)cc2)s1 +CCOC(=O)CN(CC)C(=O)c1cc(Br)c[nH]1 +CC(Cc1ccccc1)c1nc(-c2ccc(C#N)cn2)no1 +CC1CN(Cc2cc(=O)c(O)cn2Cc2ccncc2)CC(C)O1 +CCN1CCN(C(=O)COc2cccnc2)C(C)C1=O +COCCCNC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CS(=O)(=O)Nc1ccc(C(=O)c2cccs2)cc1 +Cc1ccc2cc(CN(C)C(=O)c3ccccc3F)c(=O)[nH]c2c1 +CC(C)COc1ncc(CNC(=O)C2CCC2)cc1Cl +CC(C)c1nc(S(=O)(=O)N(Cc2ccccc2)CC(F)F)c[nH]1 +COc1ccc2nnc(CCC(=O)Nc3cc(C)ccn3)n2n1 +COc1ncc(C(=O)NCc2ccccc2C)cn1 +N#Cc1ccccc1OCC(=O)N1CCN(Cc2ccccn2)CC1 +COc1ccc(S(=O)(=O)NC(C)C(=O)NC2CCCCC2)cc1 +CCc1nc2c(N)cccc2n1CC(=O)Nc1ccccn1 +CN(CCc1ccccc1)C(=O)NCC1CCCO1 +COc1ccc(CC(=O)Nc2ncccc2CO)cc1 +CN1CCC2(CN(C(=O)c3cccn3C)CC2c2ccccc2)C1=O +COc1ccc(NC(=O)CNC(=O)c2cccc(Cl)c2)cc1OC +Cc1nn(C)c2ncc(NC(=O)NC3CCCc4c3cnn4C)cc12 +CCOC(=O)CC(C)CNC(=O)NC1(C)Cc2ccccc2C1 +COc1ccc(Cc2nnc(SC3CCCCC3=O)o2)cc1 +C=CCN(Cc1ccccc1)C(=O)Nc1cccnc1 +CCc1ccc(S(=O)(=O)NC(C)c2ccc(C)o2)s1 +COc1ccc(CNC(=O)c2cccc(OC)c2O)cn1 +O=C(c1ccoc1)N1CCN(CCn2nc3ccccn3c2=O)CC1 +N#Cc1ccc(S(=O)(=O)N2CCNC(=O)C2c2ccccc2)cc1 +Cc1ccc2cccc(NC(=O)c3cccs3)c2n1 +CN(Cc1ccc(C(F)(F)F)cc1)C(=O)c1cccc(F)c1 +CC(NC(=O)c1ccc2c(c1)NC(=O)CS2)c1ccc(F)cc1F +CC1CCN(C(=O)C(C#N)Cc2ccc(C#N)cc2)CC1 +Nc1ncnc2c1ncn2C1OC(CO)C(O)C1(N)O +CC(C)(C)c1cnc(CNC(=O)c2ccnc(OC3CCC3)c2)o1 +COc1ccc(NC(=O)Nc2cccc(C#N)c2)cc1OC(F)F +Cc1nn(-c2ccccn2)c2ncc(C(=O)N(C)C)cc12 +CCc1cc(N2CCN(c3ccccc3C#N)CC2)n2nccc2n1 +CCOCCN1CC23C=CC(O2)C(C(=O)N2CCNC(=O)C2)C3C1=O +Cn1c(-c2ccccc2Cl)cn2cc(C(=O)NCCO)nc2c1=O +O=C(Cn1cnnn1)N(Cc1ccc2c(c1)OCO2)C1CCCCC1 +CC(c1cccc(O)c1)N(C)Cc1cnc(-c2ccccn2)s1 +Cc1oncc1C(=O)N1CC(Oc2cccnc2)C2OCCCC21 +Oc1ccc2c(c1Cl)C(c1ccc(F)cn1)NCC2 +COc1cc(C)c(C(=O)Nc2ccccc2C#N)cc1OC +CCc1ccc(OCC(=O)N2CCN(CC(=O)NC(C)C)CC2)cc1 +CC(=O)c1ccc(S(=O)(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +Cc1ccc(Oc2ncccc2CNCc2ccccn2)c(F)c1F +CC1CN(C(C)CNC(=O)CCc2ccsc2)CC(C)O1 +CC(=O)c1csc(NC(=O)c2cncn2-c2ccccc2)n1 +CC(=O)NCc1ccc(C(=O)COc2ccc(C(N)=O)cc2)s1 +COc1cc(-c2ncnc(C)c2N)c(OC)cc1C +CS(=O)(=O)c1ccc(-c2[nH]nc3c2CCC3)c(Cl)c1 +CCc1ccc(CN2CCN(C(=O)c3cc(C)no3)CC2)o1 +Cc1cc(NC(=O)NCc2ncn(C)n2)ccc1OC(C)C +CCc1onc(C)c1NC(=O)NC(C)Cc1c(C)noc1C +CCn1c(NC(=O)c2cnc3c(cnn3C(C)C)c2)nc2ccccc21 +O=C(NCCN1CCOCC1)Nc1cccc(Cn2cccn2)c1 +CC(C)c1cc(=O)n(CC(=O)NCCn2ncccc2=O)cn1 +COc1ccc(OC)c(-c2nc3ccc(C)cn3c2CO)c1 +O=C(CNc1ccccc1F)NCc1ccc2c(c1)OCO2 +CCc1nnc(NC(=O)c2cn(C)c3ccc(Cl)cc3c2=O)s1 +Cc1ccc(N(CC(N)=O)C(=O)c2ccccc2C)cc1 +CC(NC(=O)CCCNC(=O)c1ccsc1)C1CCCCC1 +O=c1ccc2cc(S(=O)(=O)NC3CCCC3)ccc2o1 +CCCCNc1nc(-c2cn(C)nc2C)cc(C(F)F)n1 +CC(NC(=O)c1cccc(C#N)c1)c1ccc(S(C)(=O)=O)cc1 +COc1ccccc1N1CCC(CNC(=O)NCc2cccnc2)C1 +O=C(Cn1cnc2ccccc2c1=O)c1cccc(Br)c1 +COC(=O)Cn1cc(NC(=O)c2cccc(C)c2)cn1 +CC(=O)NC1CCCN(C(=O)c2ccc(NC(=O)C(C)C)cc2)C1 +CCC(=O)Nn1cnc2c(cnn2-c2cccc(Cl)c2)c1=O +Cc1nc(N2CC(NC(=O)CCC(F)(F)F)C(C(C)C)C2)no1 +CC(C)(C)NC(=O)CNC(=O)NCc1cccc(Cl)c1 +COC(=O)c1ccc(Cn2c(C)nc3ccccc32)cc1 +CC(=O)N1CCN(C(=O)c2ccc3c(c2)NC(=O)CCS3)CC1 +CCOC(=O)c1cc2cc(CC(=O)c3ccc(O)cc3O)ccc2o1 +Nc1ncc(C(F)(F)F)cc1N1CCc2ccccc2C1 +CCNC(=O)c1cnc(-c2ccc(OC(C)C)cc2)nc1N +CN(C)S(=O)(=O)N1CCC(C(=O)NCc2cccnc2)CC1 +C=CCNc1c(C)c(C)nc2cc(-c3ccc(OC)c(OC)c3)nn12 +CCOC(=O)C(C)Sc1ncc(OC)c(OC)n1 +O=C(c1ccc(NCc2ccccc2)nc1)N1CCCC1 +Cc1n[nH]c(C)c1C(C)N(C)C(=O)c1cc(C(C)C)on1 +Cc1nc(NCc2ccc(F)cc2)cc(C2COCCN2)n1 +CSc1ccc(Cl)cc1NC(=O)c1ccco1 +CC1(C)CN(C(=O)Nc2cc(C(F)(F)F)ccc2F)CCO1 +Cn1ccnc1C(=O)C1CCCN(Cc2nc3ccccc3n2C)C1 +O=C(Nc1c(-c2ccco2)nc2ccccn12)C1CCCC1 +Cc1ccc(N2CC(CNC(=O)Cc3cccs3)CC2=O)cc1 +Cc1nc(C(N)c2ccc(O)c(F)c2)sc1C +COc1cc(C)ccc1C(=O)N1CCC(C(C)N2CCOCC2)CC1 +Cn1c(-c2ccc3c(c2)OCCO3)ccc(C(C)(C)O)c1=O +CC(NC(=O)C(c1ccccc1)N1CCCC1)C(=O)N1CCOCC1 +CC(C(=O)N1CCc2c(nc(N(C)C)[nH]c2=O)C1)n1cncn1 +CCC(C)(NC(=O)c1ccccc1)c1nc(C)c(C(=O)NC)s1 +O=C(NC1CCCCC1)C1CCCN(c2cnccn2)C1 +COc1cccc2c(C)c(C(=O)NC3(C#N)CCCC3)oc12 +CCOc1ccccc1NC(=O)C(N)c1ccccc1 +O=C(NCc1ccccc1F)c1ccc(S(=O)(=O)NC2CC2)o1 +COc1ccc2nc(-c3ccc(N)nc3)sc2c1 +CN(CC(=O)N1CCOCC1)C(=O)Cc1ccc(-n2cccn2)cc1 +COC(=O)c1noc(C(=O)Nc2cc(C)ccn2)c1N +CC(C)CCC(=O)Nc1ccccc1S(C)(=O)=O +CCOC(=O)CCC1NCCc2ccc(F)c(F)c21 +Cc1ccc2c(c1)NC(C(=O)Nc1cccc(C)c1C)NS2(=O)=O +Cc1cc(NCCCn2c(=O)c(C)nc3ccccc32)ncn1 +N#Cc1ccc(-c2noc(-c3noc4c3CCCC4)n2)nc1 +Cn1cnc(CNC(=O)NCCOc2ccc(F)c(F)c2)n1 +COC(=O)c1c(C)[nH]c(C(=O)NC2CCCCC2)c1C +CC(C)NC(=O)COC(=O)C1CCN(c2cnccn2)CC1 +COCCNc1cnc(CC2CCCN(C(C)=O)C2)cn1 +CCCCn1c(SCC(=O)NCC)n[nH]c1=O +Cc1ccc(-c2nc(CN3CCNC(=O)C3)cs2)cc1 +Nc1ccc2c(c1)OCC(=O)N2Cc1c(F)cccc1Cl +CCOc1ccc(S(=O)(=O)n2ccc(C)n2)cc1C(C)C +C=C(C)CSc1nnc(Cc2ccc(OC)cc2)o1 +Cc1nnnn1-c1ccc(C(=O)NCc2cccnc2)cc1 +O=C(NCC(=O)N1CCn2c(cccc2=O)C1)NC1CCCCC1 +Cc1csc(=O)n1CC(=O)OCCCc1ccccc1 +CCOc1cc(N2CCCCC2CNC(=O)OC(C)(C)C)ncn1 +CC1CN(CC(=O)Nc2ccc3c(c2)OCO3)CC(C)O1 +Cc1ccc(C(=O)Nc2ccc3c(c2)OCCO3)c(O)c1 +Cc1nc(C(NC(=O)c2cc(F)ccc2F)c2ccccc2)n[nH]1 +CNC(=O)c1ccc(NC(=O)NCCCC(N)=O)cc1 +CCS(=O)(=O)NCC(=O)N(C1CC1)C1Cc2ccccc2C1 +COc1ccc(Cl)c2c1CCNC2c1ccoc1 +CCN1C(=O)c2cc(Cl)ccc2NC1c1c(C)nn(C)c1C +Cc1nc(COc2cccc(C(=O)N3CCOCC3C)c2)cs1 +Cc1nc(C(=O)NCC#Cc2ccccc2F)cs1 +CC(C)C(NC(=O)c1cnc(N2CCOCC2)nc1)c1cccs1 +O=C(CCSc1ccccc1)Nc1nnc(C2=COCCO2)o1 +O=C(Nc1cccn(Cc2ccc(F)cc2)c1=O)N1CCCC1CO +Cc1ccccc1CNC(=O)Nn1cnc2ccccc21 +CC(C)(CO)NC(=O)C(Cc1ccc(O)cc1)c1ccccc1 +CC(C)CC(=O)N1CCOC(c2cccc(OC(F)F)c2)C1 +CC(C)(CO)NC(=O)c1ccc(OCC(N)=O)cc1 +CN(C(=O)c1cccn2ccnc12)c1ccccc1F +CC(C)C(=O)NC1CCN(C(=O)c2ccc3cnsc3c2)C1 +COc1ccccc1-n1nnnc1SCC(=O)c1ccc(F)cc1 +CCc1nnc(CN2CCCc3cc(F)c(F)cc32)o1 +COc1ccc(NC(=O)NCCOc2ccccc2)c2cccnc12 +CC(=O)NC(C)C(=O)NCc1ccc(NC(=O)c2ccco2)cc1 +COc1ncccc1CNC(=O)C(C)Sc1nncn1C +O=C(CCN1CCOC1=O)Nc1cc(Cl)c(Cl)cc1Cl +Nc1nn(COc2ccc(Br)cc2)cc1Cl +CC(NC1=NS(=O)(=O)c2ccccc21)C1CC1 +O=C(NCC(=O)N1CCCC1)c1n[nH]c(=O)c2ccccc12 +O=C(CN1CCN(c2cccc(Cl)c2)C1=O)NCC(F)(F)F +Cc1oc(C(=O)N(C)C2CCC(C)(C)CC2)cc1S(N)(=O)=O +CCOC(=O)c1cc2c3ccccc3n(C)c2nc1N1CCOCC1 +Cc1noc(C)c1CC(=O)N1CCC(Oc2ccccc2)CC1 +Cc1cc(NC(=O)NCCS(=O)c2ccccc2)n(C(C)(C)C)n1 +CS(=O)(=O)c1ccc(NC(=O)NC2CCOc3ccccc32)cn1 +CC(C)C(=O)Nc1nc(CC(=O)Nc2cccn(C)c2=O)cs1 +CCC(=O)Nc1cccc(C(=O)Nc2nc(CC(N)=O)cs2)c1 +CCc1ncc(C(=O)N2CCC(C(O)Cc3ccccc3)CC2)cn1 +CC1Cc2cc(S(N)(=O)=O)ccc2N1C(=O)Cn1ccnc1 +CC(NC(=O)c1n[nH]c2ccccc12)C(=O)NC(C)(C)C +COC(=O)C(CC(C)C)NC(=O)c1c(C)nn2c(C)cc(C)nc12 +CC(C)NC(=O)N1CCCC(C(=O)NCCC2=CCCCC2)C1 +N#Cc1ccc(NC(=O)NCCNC(=O)Nc2ccc(C#N)cc2)cc1 +COc1ccccc1-c1nnc(CSc2ccccc2O)o1 +CN(C)C(=O)c1cc(NC(=O)NCc2ccc3c(c2)CCC3)ccn1 +O=C(OCc1ccoc1)c1ccccc1Cn1cncn1 +C=CCCCN(C)C(=O)C1CCCN(C(=O)c2ccc(C)cc2)C1 +COc1cc(Cl)cc2cc(C(=O)Nc3cnc4n3CCCC4)oc12 +CC(C)C(=O)N1CCCC(c2ccnc(Nc3ccccc3)n2)C1 +CC(C)c1ccc(C(=O)Nc2ccc(Cl)cc2)c(N)n1 +CCOC(C)c1nc(Cn2nnc3ccccc3c2=O)cs1 +COc1ccc2[nH]c(SCc3ncc(C)c(OC)c3C)nc2n1 +CCC(CC)c1nnc(NC(=O)N2CCCC2c2ccncc2)s1 +O=C1CCCN1c1ccc(NCCCc2ccccc2)cc1 +NC(C(=O)NC1CC1)c1ccc(Cl)cc1Cl +O=C(Nc1nc2c(s1)CN(C(=O)C1CC1)CC2)C1CCC1 +Cc1ccc(NC(=O)COC(=O)CC(C)c2ccccc2)c(Cl)c1 +COc1ccccc1OCC#CCNC(=O)C1CCN(C(C)=O)CC1 +COc1ccc(N(C)S(=O)(=O)c2cccc(Cl)c2C)cn1 +Cn1nnnc1SCc1cc(Cl)ccc1OC(F)F +COc1cc(C)c(S(=O)(=O)N(C)CCO)cc1C +CC(C)CCc1noc(CN2C(=O)c3ccccc3CS2(=O)=O)n1 +CCC(=O)OCc1cc(=O)n2c3c(sc2n1)CCCC3 +CC(NC(=O)N1CCC(c2ccccc2)CC1)c1nncn1C +Cc1cc(COC(=O)c2csc(S(N)(=O)=O)c2)no1 +CN(Cc1ccccc1N1CCCC1)C(=O)c1ccc2[nH]nnc2c1 +CC(=O)NC(C)C(=O)NC1(C(=O)Nc2ccc(C)cc2)CCCC1 +COc1ccc(CCC(=O)N2CCCC2c2nc(C)no2)cc1 +CCCNc1nc(C)nc2oc(C)c(C(=O)OCC)c12 +O=C(C1CC1)N1CCN(Cc2nnnn2-c2cccc(F)c2)CC1 +CN(C)c1ncccc1NC(=O)COc1ccc2c(c1)CCC(=O)N2 +COc1ccc(-n2c(SC)nc3ccccc3c2=O)cc1 +CCN(Cc1ccccc1)C(=O)CCC(O)c1ccc(C)cc1 +Cc1ccc(C(=O)N2CCCC(C(N)=O)C2)cc1N +CCCCc1ccc(NC(=O)CSc2cn[nH]c(=O)n2)cc1 +O=C(NCC1CCCCO1)c1ccc(-c2ccco2)[nH]c1=O +CCOC(=O)C1CCC(=O)N1c1ccc(F)c(F)c1 +COC(=O)c1sc(N2CCOCC2)nc1-c1ccccc1 +c1nc2c3c4c(sc3nc(N3CCOCC3)n2n1)CCC4 +COc1ccccc1NCCC(O)c1ccc(C)c(N)c1 +CN(CC(=O)Nc1ccc(-c2ncc[nH]2)cc1)C(=O)OC(C)(C)C +CS(=O)(=O)c1cccc(C(=O)OCC2CC2(Cl)Cl)c1 +CC(=O)c1nc(-c2cccs2)n(-c2ccc(C)cc2)n1 +CC(=O)Nc1cccc(NCC(=O)NC2(C#N)CCCC2)c1 +CCC(=O)c1ccc(OCC(=O)Nc2ccccc2)cc1 +CCn1cnnc1-c1cccc(NC(=O)c2ccc(OC)nn2)c1 +Cc1ccc(CNC(=O)c2ccc3c(c2)OCO3)cn1 +COCc1nc(C)cc(N2CCC(NC(=O)c3occc3C)CC2)n1 +CC(=O)N1CCN(C(=O)C(C)(C)c2ccc(Cl)c(Cl)c2)CC1 +O=C(Nc1ccccc1F)c1cc(-c2ccccc2)no1 +OCc1nc2ccccc2n1CC(O)COc1ccc(Cl)cc1 +Cc1ccc(C(=O)NC(CC(F)(F)F)c2ccccc2)c(=O)[nH]1 +CCOC(=O)c1nn(-c2nc3ccccc3[nH]2)c2c1CNCC2 +CC(O)CCC(=O)Nc1cccc(Cl)c1Cl +Cn1c(N)nnc1SCc1nccn1C(F)F +CC(C)c1ccccc1OCCn1c(=O)oc2ccc(N)cc21 +CC(c1cc(F)ccc1F)N(C)C(=O)CCSc1nnnn1C +N#CCCN(Cc1cccnc1)C(=O)c1ccc2c(c1)CCC2 +O=C1CCCN1c1cccc(NCc2ccc(CO)o2)c1 +Nc1ccc2c(c1)N(C(=O)c1ccc(Br)cn1)CC2 +CC(C)(C)OC(=O)c1cncc(Br)c1 +CC(=O)NC(CC(=O)Nc1cccc(Cl)c1F)c1cccs1 +CNC(=O)c1cccc(CN2CCc3cc(S(N)(=O)=O)ccc32)c1 +Cc1noc(C)c1S(=O)(=O)Nc1ccc2c(c1)CCC2 +Cc1csc(NC(=O)NC(C)c2cccc(OC(F)F)c2)n1 +CCOCc1ccccc1NC(=O)NC1CCCC1C(=O)OC +COc1cccc(CCNC(=O)c2ccoc2C)c1 +Cc1c(-c2ccnc(N3CCCCC3)n2)nnc2ncnn12 +C=CCOC(=O)C1CCC(O)CN1C(=O)OC(C)(C)C +CC(=O)c1c(F)cccc1NCC(C)(C)C(N)=O +COCCN1CCCC2(CCN(C(=O)c3c[nH]c(C)cc3=O)C2)C1=O +COc1ccc(CNC(=O)CCc2c(C)nc(C)[nH]c2=O)cc1O +CC(=O)NC(C(=O)OCc1ccc2[nH]nnc2c1)C1CCCC1 +COc1ccc(C(=O)OCC(=O)Nc2ccccc2)cc1N +O=C1Nc2cccc(Br)c2C1NCC(F)(F)F +CCCCn1nc(C(=O)NC2CCCn3nc(CC)nc32)ccc1=O +CCNc1ncnc(Oc2ccc(Cl)c(C)c2)c1N +Cc1ccnn1CC(=O)NC1CCCc2nc(-c3ccccc3)ncc21 +CC(C)c1nnc(NC(=O)Cc2ccccc2F)s1 +Cc1ccc(C(=O)c2c[nH]c3ncccc23)cc1F +NC(=O)c1cc2cc(F)ccc2nc1C1CCN(C(=O)C2CC2)CC1 +C#CCN(Cc1ccc(F)cc1)C(=O)CCSc1ccccn1 +O=S(=O)(NCC1CCOC1)N1CCCCCC1 +Cc1oc(-c2ccsc2)nc1CC(=O)NC(C)C(=O)N(C)C +Cc1nnc(SCC(=O)Nc2c(Cl)cccc2Cl)n1N +COC(=O)c1ccc(C(=O)Nc2ccc3c(c2)OCCCO3)s1 +CC(C)Cc1nc(C(=O)N(CCC#N)CCC#N)cs1 +Cc1c(CC(=O)N2CCC(C)CC2)c(=O)oc2cc(O)cc(O)c12 +CS(=O)c1ccc(C(=O)NCC(C)(C)c2ccncc2)cc1 +O=C1OCCN1CCN1CCN(C(=O)c2n[nH]c3ccccc23)CC1 +O=C(Nc1cccc2cn[nH]c12)c1[nH]nc(C2CC2)c1Cl +CSc1cccc(NC(=O)N2CCCC(CO)C2)c1 +O=C(NCC1CCCC(CNC(=O)N2CCCC2)C1)N1CCCC1 +CCNc1nnc(S(=O)(=O)CC(=O)NCc2ccco2)s1 +Cn1ncc2c(=O)n(CC(=O)NCCc3cccs3)cnc21 +COc1ccc(-n2ncc3c(NC4CCCC4)ncnc32)cc1 +Cc1ccc(S(=O)Cc2cccc(S(=O)(=O)N(C)C)c2)nc1 +COc1ccccc1C(=O)NCCNC(=O)c1ccccn1 +Nc1ccc2c(c1)N(CC(=O)Nc1ccccc1)CCS2 +Cc1ncc(C(C)NC(C)c2ccccc2-n2cccn2)s1 +Cc1nc(C)c(C(=O)OCC(=O)NC2C3CC4CC(C3)CC2C4)s1 +CCOC(=O)c1cnn(C2CCCN(C(=O)C3CC3(C)C)C2)c1 +CCC(=O)NC(CC)c1ccccc1OCC(=O)N1CCCC1 +CC1(C)C(NC(=O)CCC(=O)c2ccc(F)c(F)c2)C2CCOC21 +Cc1cc(N)c2onc(CC(=O)NCCc3ccccc3)c2c1 +COCCNC(=O)C(C)Sc1nnnn1C(C)(C)C +COC(=O)C1(NC(=O)c2cccnc2OC)CCCC1 +COc1ccc(NC(=O)NCC2(CO)CC2)cc1 +Cn1ncc(SCc2ccccc2)c(Cl)c1=O +Cc1nc(-c2cccc(CNC(=O)c3cc(C(N)=O)c[nH]3)c2)n[nH]1 +COCCNC(=O)c1ccc(Cl)c(NC(=O)CC(C)(C)C)c1 +Cc1ccc(CN(C)C(=O)c2scnc2C2CC2)cc1 +COC(=O)COC(=O)c1ccc(C)c(NC(=O)c2ccco2)c1 +CNC(=O)c1ccc(NCc2ccccc2)c(C)c1 +COC(=O)c1ccc(NC(=O)c2ccc(NS(C)(=O)=O)cc2)cc1 +CC1(c2ccc(S(C)(=O)=O)cc2)COCCN1 +CC(=O)c1cc(-c2ccc3c(c2)OCCCO3)[nH]c1C +Cc1cc(NC(=O)CSc2nncn2CC(F)(F)F)no1 +COc1ccccc1-n1nnc(C(=O)Nc2ccccc2Cl)c1N +CCOc1cccc2cc(C(=O)Nc3ccccc3)c(=O)oc12 +Cc1cc(NC(=O)CSc2nc(-c3ccccc3F)n[nH]2)n(C)n1 +COc1cc(CNC(=O)c2oc3c(C)cccc3c2C)ccn1 +Cc1ccc2c(CC(=O)N(C(C)C)C3CCOCC3)c[nH]c2c1 +CC1CCCCN1C(=O)c1cccc(CCC(C)(C)O)c1 +N#CCCc1c(C(F)(F)F)nc2ccncc2c1Cl +Cc1oc(-c2ccccc2Cl)nc1CN(C)Cc1ccncn1 +Cc1c(Cl)cccc1-n1ncc2c(=O)[nH]cnc21 +CC(c1cccs1)N(C)C(=O)CN1CCCCC1=O +Cc1noc(C)c1COc1ccc(C(=O)N(C)C2(C#N)CCC2)cc1 +CC(C)N(Cc1ccccc1)C(=O)Cn1ncn2cccc2c1=O +CCCc1nc(C(=O)N2CCCN(c3ccc(F)cc3)CC2)cs1 +O=C(NCC(=O)N1CCc2ccccc21)c1cc2scnc2[nH]1 +CC1=CCC2CN(C(=O)c3coc4c3C(=O)CCC4)CC2C1 +CCCc1nn2c(CO)c(-c3cc(C)ccc3OC)nc2s1 +CCN(CC)C(=O)N1CCN(Cc2nc(C(C)C)no2)CC1 +CCC(O)Cn1ccc(-c2cccc(-c3cnccn3)c2)n1 +COc1ccc(CNC(=O)c2nc3nccc(C)n3n2)cc1OC +Cc1ccc(NC(=O)c2ccc[nH]2)cc1NC(=O)c1ccncc1 +CCC1c2ccsc2CCN1C(=O)CCc1c(C)noc1C +O=C1NCCN(C(=O)CCn2cccn2)C1c1ccccc1Cl +Cc1cc(C)c(S(=O)(=O)NCCNC(=O)c2ccco2)c(C)c1 +CCCCNC(=O)CSc1nc2ccccc2n2c(C)nnc12 +NC(=O)CSc1nnc(-c2cc(-c3ccc(Cl)cc3)n[nH]2)n1N +Cn1cnc(CNC(=O)NCCNc2ccc3ccccc3n2)n1 +Cc1ccc2nc(NC(=O)CCCCNC(N)=O)sc2c1 +COCCn1cc(C(=O)N2CCCCC2)c(=O)c2c(N)cccc21 +O=C(OCCN1CCCC1=O)c1ccc(Cn2cccn2)cc1 +O=C(Nc1ccccc1F)NC1CCOc2ccccc21 +CC(C)CCC(=O)Nc1ccc(F)cc1C#CCO +CC(NC(=O)CCn1ncc2ccccc21)C(=O)N1CCCCC1 +Cc1cc(C)cc(CSc2ncnc3c2cnn3C)c1 +CC1CC(C)CN(C(=O)c2cn3ccccc3n2)C1 +C=CCN1C(=O)c2ccccc2NC1c1ccoc1C(=O)OC +CCCCCn1nnc(S(=O)(=O)c2ccccc2)c1N +CC(Oc1ccccc1C(F)(F)F)C(=O)C(C#N)c1ccccn1 +N#CCCn1c(=O)c(-c2ccccc2)nc2cc(F)ccc21 +O=C(NCc1cccnc1)NCc1cc(Br)cs1 +COC(=O)C1CCCN1C(=O)c1cccc(Cl)c1N +COc1cc(C)ccc1OCc1nc(C(=O)N2C(C)CCC2C)co1 +CNC(=O)c1cc(S(=O)(=O)NC2CCCC2)cs1 +CN(C(=O)Cc1ccsc1)c1ccc(C(N)=O)cc1 +CCn1c(SCc2nnc(C3CC3)o2)nnc1-c1ccccc1C +O=C(c1ccncc1)N1CCC(Nc2nc3ccccc3o2)CC1 +O=C(CC1CCCC1)NCC(=O)Nc1cccc(-c2cn[nH]c2)c1 +CCc1ccc(-n2c(Cc3nc(C)cs3)n[nH]c2=O)cc1 +CCCn1nc(-c2ccc(CC)cc2)cc(CO)c1=O +O=C(NCCc1ccccc1Cl)NC1CCC(O)CC1 +Cc1cc(CN(C)C(=O)CN2C(=O)OCC2c2ccccc2)n(C)n1 +CCCS(=O)(=O)N1CCCCC1C(=O)N(C)Cc1cc(C)on1 +Cc1nnsc1C(=O)N1CCN(CC(=O)c2cccs2)CC1 +Cc1cc(NC(=O)C(C)N2CCN(c3nc(C)cs3)CC2)on1 +CCc1c(C)nc2nncn2c1NCc1ccc(Cl)cc1 +Cc1ccnc(NC(=O)Cc2cc(=O)oc3cc(C)ccc23)c1 +CC(=O)Nc1cc(NC(=O)NC(C)(C)C)ccc1F +O=C(NCc1ccc2c(c1)OCO2)c1cnc(N2CCOCC2)nc1 +O=C(Oc1ccc(N2CCOC2=O)cc1)c1cnn(-c2ccccc2)c1 +CCOc1ccc(CNC(=O)N2CCOC(C)C2)cc1F +O=C(c1ccc(Cl)cc1Cl)N1CCC2(CC1)OCCO2 +C=CCc1ccccc1OCC#CCNC(=O)C1CC(=O)N(C)C1 +Nc1nncc(-c2ccccn2)c1C(=O)NCc1ccccc1 +CCNc1nnc(-c2ccc(C)n(C(C)C)c2=O)s1 +Cn1c2ccc(N)cc2n2c(C3CCCCC3)nnc12 +Cn1c(=O)c2c(ncn2CC(=O)Nc2nncs2)n(C)c1=O +CCc1onc(C)c1NC(=O)c1ccn(C2CCCC2)n1 +CC(C)c1ccc(S(=O)(=O)c2nonc2N)cc1 +O=C(Nc1nnc(Cc2ccc(F)cc2)s1)c1ccco1 +CCCC(C)NC(=O)C(C)S(=O)c1ccc(C)cn1 +CN(C(=O)CC1OCCc2ccccc21)c1cccc2ncccc12 +COc1cc(Br)cc(C)c1NC(=O)c1cn[nH]c1 +CC(=O)c1ccc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)cc1 +CC(COCc1ccccc1)C(=O)N1CCCC(c2nccs2)C1 +Cc1ccc(-c2nnc(SCC(=O)N3CCC(C)CC3)n2C)cc1 +Cc1ccc(S(=O)(=O)NC2(C#N)CCCC2)cc1C +COC(=O)CS(=O)(=O)c1ccc(C(F)(F)F)cn1 +CCOc1ccnc(N(C)CCc2ccncc2)n1 +CCCCc1noc(CN2CCc3cc(OC)c(OC)cc3C2)n1 +COc1ccc(-c2noc(NCc3ccc(O)c(F)c3)n2)cc1OC +Cc1c(N)cncc1C(=O)Nc1cccc(C#N)c1 +O=C(c1cnn(-c2ccccc2)c1C1CC1)N1CCCCC1 +CCN(CC(=O)NC1CC1)S(=O)(=O)c1ccc(Cl)cc1 +Cc1nn(Cc2ccccc2F)c(C)c1NC(=O)NC1CCCC1 +Cc1cc(O)c(C(C)C)cc1NC(=O)CCCc1nc(C2CC2)no1 +Cc1nc(N2CCCC2=O)sc1C(=O)Nc1ccccc1 +C=CC(CC(=O)Nc1c(NC)c(O)nc(=O)n1CC)c1ccccc1 +COc1ncccc1C(=O)N1CCOC(c2ccccc2Cl)C1 +CN(C(=O)c1ccc(-n2cccn2)cc1)c1ccc(F)c(F)c1 +CN(Cc1ccccc1)C(=O)CNC(=O)c1cc(F)cc(F)c1 +Cc1cccc(C(=O)NCC(=O)Nc2cccc(F)c2)c1 +CN1CC(C(=O)Nc2ccc(N(C)C)cc2C(F)(F)F)CC1=O +O=C(CCC1CCOCC1)NC1CCCN(Cc2ccccc2)C1=O +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(C(C)C)cc1 +Cc1ccc(Cl)cc1N1CCN(C(=O)CCCn2cncn2)CC1 +CCCn1c(C)nnc1SCC(=O)C(C)CC +N#CCSc1nc2ccccc2c(=O)n1CCN1CCOCC1 +CC(=O)Nc1nc(C(=O)N2c3ccnn3C(C)CC2C)cs1 +CNc1ncc(Br)c2c(F)c(F)c(F)cc12 +O=C(Nc1ccncc1)N1CCN(c2nccs2)CC1 +Nc1c(-c2ccccn2)nc2scc(-c3cccnc3)n12 +Fc1ccc(-c2nn3c(C4CC4)nnc3s2)c(F)c1F +CCc1ccccc1OCCCN1CCCS1(=O)=O +CCN1CC(C(=O)Nc2ccc(Br)cn2)CC1=O +Fc1cccc2ncnc(NCCCn3ccnn3)c12 +Cc1cc(Br)ccc1NC(=O)N(C)Cc1cnn(C)c1 +Cc1cn(CCNc2nc(C(C)(C)C)nc3c2cnn3C)nn1 +CCc1nnc2n1CCN(CC(=O)Nc1ccc(Cl)cn1)C2 +O=S(=O)(NCc1ccn(-c2ccccc2)n1)c1cc(F)cc(F)c1 +O=C(NC1CCCCC1)c1ccc(NC(=O)c2cc[nH]n2)cc1 +CN(Cc1ccccc1Cl)C(=O)C1CCC(=O)N1 +O=C(Nc1cn[nH]c1)C1(c2cccc(F)c2)CCOCC1 +CC1CN(S(=O)(=O)NC(C)c2nnc3ccccn23)CC(C)O1 +CC1C(=O)N(c2ccc(F)cc2)CCN1C(=O)C1CC1 +Cc1nc(COCc2ncc[nH]2)nc2ccccc12 +COc1ccc(S(=O)(=O)N(C)Cc2ccccc2N)c(C)c1F +Cc1nn(C)c(C)c1CNC(=O)C1(C)Sc2ccccc2NC1=O +CCc1ccc(-c2cn(CCc3c[nH]c4ccccc34)nn2)o1 +COc1cnc(NCCSc2cnn[nH]2)nc1-c1ccnn1C +CC1C(=O)N2CCCc3cc(S(=O)(=O)NC4CC4)cc1c32 +Cc1nc(C(C)(C)NS(=O)(=O)N2CC(C)OC(C)C2)sc1C +N#Cc1ccc(C(=O)OCC(=O)c2ccc[nH]2)cc1 +COc1cc(C(=O)Nc2cccc(Cl)c2C)ccc1OCC(N)=O +COc1ccc(C2NCCc3c(OC)cccc32)c(F)c1 +CNC(=O)c1cccc(NC(=O)CNc2ccc(C)cc2)c1 +COCC(=O)N1CC(C(C)C)NCC1c1ccccc1 +CNC(=O)c1ccc(OC)c(NC(=O)NC(C)c2ccccc2)c1 +CCCNC(=O)c1cccc(NC(=O)CSc2nncs2)c1 +CC(NC(=O)NCC1CCCO1)c1cccc(O)c1 +O=C(COC(=O)c1ccccc1O)NCC1CCCO1 +CC(CC(=O)Nc1ccc(Cl)c(S(N)(=O)=O)c1)C1CC1 +O=C(c1ccc[nH]1)N1CCCN(C(=O)C2CC3CCC2C3)CC1 +Cc1nnc2ccc(C(=O)Nc3ccccc3)cn12 +Cc1cc(F)ccc1S(=O)(=O)N(C)Cc1c(C)noc1C +COCc1nc(C)c(C(=O)N(C)C(CO)C(C)(C)C)s1 +CC(C)Oc1ccc(CNC(=O)Cn2c(=O)[nH]c3ccccc32)cn1 +CCOc1ccc(C2CCCN2C(=O)c2cc(C3CC3)on2)cc1 +Cc1cc(COC(=O)CCN2C(=O)COc3ccccc32)no1 +COc1ccc(-c2nc(CN3CCOC(C)(C)C3)cs2)cc1OC +Cc1ccc(C(N)=O)cc1NC(=O)NCc1cc2ccccc2o1 +CN(Cc1ccccc1Br)C(=O)c1cnns1 +Nc1cc(N2CCC3(CCC(=O)N(CC4CC4)C3)CC2)ncn1 +COC(=O)C(C)N1CCc2c1cccc2C(F)(F)F +Cc1cc(C2CCCN2C(=O)Cc2ccccc2F)no1 +Cc1csc(C2CN(CC(=O)Nc3sccc3C#N)CCO2)n1 +CC1CCN(C(=O)c2ccccc2NC(=O)C2CC3C=CC2C3)CC1 +O=C(NCCOc1cccnc1)c1cc(Cl)c2c(c1)OCCO2 +O=C(Cc1cccc(O)c1)N1CCCC1c1nc2ccccc2[nH]1 +COC1CCCC1OC(=O)CSc1ccc(F)c(F)c1 +CC(C)CCNC(=O)C(O)c1ccc2c(c1)OCCO2 +Cc1ccc2nc(-c3ccc(N(C)C)cc3)nn2c1 +NC(=O)c1cccc(S(=O)(=O)Oc2ccc3c(c2)CCC3)c1 +Cc1cc(N)nc(SCC(=O)Nc2nc3ccccc3s2)n1 +CCn1nccc1CN(C)C(=O)Nc1cccc(F)c1 +Cc1noc(COc2ccc(NC(=O)c3cc(C)sc3C)cc2)n1 +CCC1CCCN(C(=O)CCc2ccsc2)C1 +CC12CCC(C(=O)Nc3ccccn3)(CC1=O)C2(C)C +CC1CCC(NC(=O)NCc2cccc(S(N)(=O)=O)c2)CC1 +O=C(Nc1ccc2c(c1)COC2)Nc1cnn(Cc2ccccc2)c1 +COC1CCCC1OC(=O)c1ccc(CNC(C)=O)cc1 +COC(=O)C(NC(=O)Cc1ccc(C)s1)C(C)C +COCCn1c(=O)[nH]c(=O)c2c(-c3ccc(Cl)cc3)ccnc21 +CC1CN(C(=O)NCCCCN(C)c2ccccc2)CC(C)O1 +CC(=O)Nc1cccc(NS(=O)(=O)c2ccccc2F)c1C +Cc1ccc(NC(=O)CN2C(=O)CSc3ccccc32)c(F)c1 +Cc1cccc(C(=O)N2CCc3cc(N)ccc32)n1 +CCN(Cc1cccs1)C(=O)Cn1nnc(-c2cccc(F)c2)n1 +CCOC(=O)NCCn1nc(-c2sc(C)nc2C)ccc1=O +COC(CNC(=O)c1c(C)nc2ccccn12)c1ccc(C)s1 +CCN(Cc1ccccc1C)C(=O)Nc1cccc(NC(C)=O)c1C +O=C(CSc1nnc2sc3ccccc3n12)n1ccnc1 +Cc1cc(C)n(Cc2ccc(C(=O)Nc3ccncc3)cc2)n1 +Cc1cccc(CCCNC(=O)C2CC(=O)N(C(C)C)C2)c1 +CCn1c(C(=O)Nc2ccc(S(N)(=O)=O)cc2)cc2sccc21 +Cc1cccc(NCc2cc(C#N)ccc2F)c1N +CCOC(=O)CCC(=O)Nc1ccc2c(C(C)(C)C)cc(=O)[nH]c2c1 +Cc1nc(C(=O)N2CCC3(CCCN(CC4CC4)C3=O)C2)cs1 +CN(CC(=O)Nc1ccc(F)cc1)C(=O)CSc1nncs1 +O=C(Cn1c(=O)oc2ccccc21)N=c1[nH]nc(-c2ccccn2)[nH]1 +Cc1cccc(OCC(=O)NC(C(N)=O)c2ccccc2)c1C +O=S(=O)(c1c(F)cccc1Cl)N1CCCC(n2cccn2)C1 +Cc1ccc(CNc2cc(C)nc3nncn23)cc1 +CCOC(=O)CNS(=O)(=O)c1cccc(Cl)c1F +Cc1csc(-c2ccc(NC(=O)NCCN3CCOCC3)cc2)n1 +Nc1ccc(-c2ccc3c(c2)OCCCO3)cc1F +CC(NC(=O)NCc1cc[nH]n1)c1ccc2c(c1)NC(=O)CO2 +Cc1cc(S(=O)(=O)Nc2ccc(F)cc2)ccc1OCC(N)=O +COC(=O)c1ccc(NC(=O)c2cccc(-c3ccoc3)c2)cc1F +O=C(NCc1cccs1)NCC1(c2cccc(F)c2)CCOCC1 +CCc1nnc(SCC(=O)Nc2cccc(Cl)c2C)o1 +O=C(Cn1cnc2ccccc2c1=O)Nc1ccccc1C(F)(F)F +Cc1ccc2c(c1Br)C(c1cc[nH]n1)NCC2 +Cc1nc(C)c(CC(=O)N(C2CC2)C(C)C(C)C)c(=O)[nH]1 +CC1CN(c2nccc(C(F)(F)F)n2)CCC1(O)C1CC1 +Cc1ccccc1NC(=O)CCS(=O)(=O)c1cccs1 +CCC(C)Sc1nnc(-c2ccc(F)cc2)n1N +Cc1ccc(C(C)C)c(OCC(=O)Nc2cc(C)on2)c1 +N#Cc1cccnc1NC1CCCN(c2ncccn2)C1 +Cc1cc(NC(=O)Nc2cc(Cl)cc(Cl)c2)on1 +CNS(=O)(=O)CCNc1cc(-c2ccccc2F)nc2ccnn12 +COc1ccc(Cl)cc1CNC(C)(C#N)C(C)C +COC(=O)CCn1nc(C)c(CN2CC(C)OCC2C)c1C +Cc1cccc(-c2nnc(C)c(N3CCCC3)n2)c1 +Cn1cc(C(=O)N2CCOC3CCCCC32)c(C(C)(C)C)n1 +CC(C)C(CC(N)=O)c1ccc2c(c1)OCCCO2 +Clc1ccc2nc(CSc3nccn3C3CC3)cn2c1 +O=C(NCC(F)(F)F)C1Cc2cc(Cl)ccc2O1 +O=C(CSc1ccccn1)Nc1cccc(F)c1 +O=C(NCc1nncn1-c1ccccc1)c1ccc(-n2ccnn2)cc1 +c1ccc(Cn2nnnc2SCc2ccc3c(c2)OCCO3)cc1 +CCc1nc(C(C)NC(=O)Nc2ccc3[nH]ncc3c2)cs1 +c1csc(-c2nc(COc3nnc4ccccn34)no2)c1 +CN1CCCN(S(=O)(=O)c2cn(C)cn2)c2cc(F)ccc21 +Cc1ncsc1-c1nc2ccccc2n1CC(=O)Nc1cc[nH]n1 +Cc1cccc(NC(=O)CNC(=O)Nc2ccc(F)c(F)c2)c1 +CC1CCCC(CNC(=O)CCCc2nnc(-c3ccccc3)o2)C1 +O=C(Cn1nnc2ccccc2c1=O)NCC1CCOC1 +Cc1ccc(C(=O)N2CCCC(CN3CCOCC3)C2)cc1 +CCc1nnc(NC(=O)COCc2nc(-c3ccncc3)no2)s1 +CC1(CNC(=O)NCc2ccnc(OC3CCC3)c2)CCC1 +O=S(=O)(Nc1cccc(CO)c1)c1c(F)cccc1F +CCC(NC(=O)c1c[nH]c(=O)c(Cl)c1)c1cccs1 +CNc1nc(-c2cnc(N3CCCC3)s2)cs1 +O=C(NC1CC1)c1cccc(NC(=O)c2cn3ccccc3n2)c1 +CCC(C#N)(CNC(=O)c1ccccc1)c1ccccc1 +CCC1CCC(NC(=O)Nc2cnc3c(c2)c(C)nn3C)CC1 +CN1CCOc2ccc(NC(=O)Nc3ccc(Cl)cc3)cc2C1=O +O=C(NCC1(O)CCCc2ccccc21)Nc1ccc(F)cc1F +CC(=O)Nc1ccc(CC(=O)Nc2nccs2)cc1 +CC(=O)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1 +N#CCC(=O)NCc1ccccc1CN1CCN(c2ccccc2)CC1 +CC(C)(C)C(=O)N1CCC(C(=O)NCc2cscn2)CC1 +COC(=O)C1CN(C(=O)c2cn(C)nc2C(C)(C)C)CCO1 +CCN(CC)C(=O)N1CC2CCC1CN(C(=O)c1ccccc1)C2 +N#Cc1cnc(SCc2ccccc2Oc2cccnc2)nc1N +CCc1ccc(CN(Cc2cccnc2)C(=O)c2oc(C)nc2C)cc1 +CC(=O)c1ccc(S(=O)(=O)N(C)c2c(F)cccc2F)cc1 +CCNc1ccccc1C(=O)N1CCCC1C(N)=O +O=C(CCNC(=O)N1CCc2ccccc2C1)Nc1nccs1 +COc1ccc(CCNC(=O)Cn2c(C)csc2=O)cc1 +COc1ccc(C(=O)N(C)Cc2ccc3c(c2)OCCO3)cc1F +N#Cc1ccccc1OS(=O)(=O)c1ccc(Cl)cc1F +O=C(NCc1cccnc1Oc1ccc(F)cc1F)c1cccnn1 +CC1CN(C(=O)c2cccc3ncccc23)C(C)CO1 +CCOC(=O)c1c[nH]c2cc3c(cc2c1=O)CCS3 +C=CCn1c2cc(C)sc2c2cnn(CC(=O)NC(C)C)c(=O)c21 +O=C(CNC(=O)N1CC2CCCC2C1)Nc1ccccc1 +O=C(Nc1ccc2c(c1)Cc1ccccc1-2)c1cnn2c1OCCC2 +CC12COC3(C(=O)Oc4ccccc4)CC1CCC32C +Cc1cccc(C(=O)NCC(=O)N2CCC(CC(N)=O)CC2)c1 +Nc1ccccc1S(=O)(=O)NC1CCC(O)CC1 +Cn1cc(C(=O)NCCOC2CCCCC2)ccc1=O +CC(C)(C)C(=O)N1CCN(CC(O)CN2CCOCC2)CC1 +CCn1nccc1C(=O)N1CCOC(C(=O)N2CCCCC2)C1 +CCC(C(=O)N(CC)CC1CCOCC1)n1cccn1 +CCC(C)N1C(=O)CCC1C(=O)NCCc1ccc(Cl)cc1 +NC(=O)c1ccc(CN(C(=O)c2cccc(Cl)c2)C2CC2)cc1 +O=C(c1cc(-c2cccnc2)[nH]n1)N1CCCCCC1 +CN(C)C(=O)c1ccc(C(=O)Oc2ccc3c(c2)CCC(=O)N3)cc1 +Cc1oc(-c2cccs2)nc1Cn1ncn(C)c1=O +CN(C)C(=O)COc1cccc(NC(=O)c2cc(F)ccc2F)c1 +CC(=O)c1cccc(OCC(=O)Nc2ccc(CC#N)cc2)c1 +Cc1c(NCc2noc(C3CC3)n2)cccc1S(=O)(=O)NC1CC1 +Cc1csc(=O)n1CCC(=O)Nc1ccc(N2CCCC2)nc1 +Cc1cc(C)n(CCC(=O)NCc2ccccc2OC(F)(F)F)n1 +COCc1c(C(=O)Nc2nnc(C3CC3)s2)oc2ccccc12 +COc1ccc(OC)c(NCC(=O)Nc2cccc(NC(C)=O)c2)c1 +Cc1cc2[nH]c(=O)[nH]c2cc1NC(=O)Nc1ccc(Cl)cc1 +C=CC(C)(C)c1cc2cc(OC)c(O)cc2oc1=O +CCC1CCCCN1C(=O)NCCCc1c(C)noc1C +Cc1ccnn1-c1cccc(NC(=O)CC2OC(=O)c3ccccc32)c1 +COc1ccc(-c2cc3nc(C)cc(C)n3n2)c(OC)c1 +CC(NC(=O)c1ccc(=O)n(C)n1)c1nc2ccccc2[nH]1 +CCn1cc(C(=O)OCc2ncc(-c3ccc(F)cc3)o2)cn1 +Brc1cccc(-c2cnc3c(n2)NCC3)c1 +Nc1c(-c2cc(F)ccc2F)nc2c(F)cccn12 +CC1(c2ccccc2)CCC(=O)N(Cc2n[nH]c(=O)[nH]2)C1 +COc1cccc2c(=O)c(C(=O)Nc3ccc(F)cc3)c[nH]c12 +Cc1csc(-n2nnc(C(=O)N3CCC4(CC3)OCCO4)c2C)n1 +CCN1CCN(C(=O)C2(c3ccc(Cl)cc3)CC2)CCC1=O +CCN1CCc2nc3ccc(C)cc3c(C(C)=O)c2C1 +O=C(COC(=O)CCn1cnnn1)Nc1nccs1 +CNC(=O)Cn1cnc(NC(=O)CCc2cccc(F)c2)n1 +Cc1ccc(OCC(=O)NCC2CCN(S(C)(=O)=O)CC2)cc1 +CC(C)(O)CCc1ccc(C(=O)NC2CCOCC2)cc1 +CCn1nc(C)c2c1cnn2CC(=O)NCc1ccco1 +CC(=O)c1cc2c(cc1NC(=O)COc1ccc(Cl)cc1)OCO2 +COC(=O)c1ccc2c(c1)CCN2Cc1c[nH]nc1-c1ccc(C)o1 +Nc1cccc(Cn2c(=O)cnc3ccccc32)c1 +CC(C)Sc1ccccc1C(=O)C(C#N)c1ccccn1 +CCN(CC)C(=O)CCNS(=O)(=O)c1cccc(Cl)c1 +CC(=O)Nc1cccc(NC(=O)Nc2cc(C)on2)c1 +CCN1CC(C(=O)Nc2cc(F)c(OC)cc2OC)CC1=O +COc1ccc(CNc2cc(C)ccc2C#N)cn1 +Cc1nc(NC(=O)Nc2cnn(C(C)(C)C)c2)sc1C +CCSc1ccc(NC(=O)c2ccc(COC)cc2)cn1 +CC(=O)N1CC(C(=O)N2CCCC2c2cc(C)ccc2C)C1 +COc1cc(C(=O)NC(C#N)C(C)(C)C)cc(OC)c1OC(F)F +COc1cccc(COCC(=O)N2CCCCC2Cn2cccn2)c1 +CCC(CC)NC(=O)C1CCCCN1C(=O)c1cccs1 +CC(C)CCC(=O)Nc1cccc(N2CCCC2=O)c1 +CCOc1cccc2c1OCC(CN1CCOCC1)C2N +COc1ccc(OC)c(C(=O)CC2C(=O)Nc3ccccc32)c1 +CC1CCCN(S(=O)(=O)NC(C)c2ccncc2)C1 +CCOCc1nc(-c2ccccc2SC)n(C)n1 +COc1ccc(S(=O)(=O)NCc2cnc(C)s2)c(C)c1F +COc1ccc2c(c1)C(c1ccc3ccccc3n1)NCC2 +C=CCn1c(=O)c(=O)n(CC(=O)NCCC(C)C)c2ccccc21 +Cc1cc(C)c(C(=O)N2CCOCC(CO)C2)c(=O)[nH]1 +O=C1Nc2cc(Br)ccc2C1NCC1CCCO1 +Cc1cc(C(=O)Nc2ccccc2F)c2c(C)nn(C)c2n1 +Cc1cc(F)ccc1NC(=O)CCCNC(=O)c1cccs1 +CN(C)c1ccccc1NC(=O)N1CCc2cc(F)ccc2C1 +CCC(=O)N1CCc2ccc(NC(=O)c3ccc(Cl)cc3)cc2C1 +O=C(CSc1cn[nH]n1)Nc1nc2ccccc2s1 +COc1ccc2c(C(=O)CN3CCc4ccccc4C3)c[nH]c2c1 +CCN(Cc1cnc2ccccn12)C(=O)COc1ccc(C)cc1 +CN(C(=O)CSc1nnnn1Cc1ccco1)C1CC1 +COc1cccc(C2CCCN2C(=O)c2cnc3ccc(C)cn23)c1 +Cc1ccc(Cl)c(OC(C)C(=O)Nc2nc(C)no2)c1 +CC(C)C(NC(=O)NCc1cccc(C#N)c1)c1nc2ccccc2[nH]1 +COc1cccc(Cn2cc(NC(=O)c3nc4ncccn4n3)cn2)c1 +Cc1cccc(OCC(=O)Nc2cccnc2)c1C +CCn1cnnc1-c1cccc(NC(=O)c2cccs2)c1 +Cn1cc(-c2nnn3c2COC(CNC(=O)CC2CCCC2)C3)cn1 +CC1CN(S(=O)(=O)c2ccccc2)C(C)CC1=O +CC1(NC(=O)CNC(=O)Cc2ccccc2)CCCC1 +CCNc1nc(C(=O)N(C)Cc2cnccn2)cs1 +Cc1nc(CSc2nc(Cc3cccs3)n[nH]2)no1 +CCC(O)c1ccc(OCC(=O)NC2CCCC2)cc1 +COC(=O)CCN(C)C(=O)COc1ccc(Br)cc1 +O=C(COC(=O)c1cc(=O)[nH]c(=O)[nH]1)NCc1ccco1 +CC1(CNC(=O)NC2CCCN(c3ccccc3F)C2=O)COC1 +CCCCNC(=O)CSc1nc2ccccc2[nH]1 +N#Cc1ccc(OC2CCN(S(=O)(=O)C3CC3)CC2)nc1 +CC(NC(=O)COc1ccc(C(N)=O)cc1)c1ccc(F)cc1 +COc1ccc(C(=O)NCC(=O)c2ccc3c(c2)CCC3)cc1 +COC(=O)Nc1cc(NC(=O)c2ccccc2OC)ccc1F +Cn1nccc1CNC(=O)NC1CCN(c2ccc(Cl)cc2)C1 +COc1ccccc1NC(=O)c1c[nH]c2c(OC)cccc2c1=O +Cc1ccccc1C1(CNC(=O)NCc2nc(C3CC3)no2)CC1 +CNC(=O)NCC(=O)N(Cc1ccccn1)Cc1ccccc1C +NC(=O)Nc1cccc(C(=O)NCCC(=O)NC2CCCC2)c1 +Cc1ncc(CNC(=O)N(C)CCOc2ccccc2F)s1 +CCn1c(C(=O)Nc2cn[nH]c2)cc2ccccc21 +CCn1nnc2cc(C(=O)NCc3ccc(C)cc3)ccc21 +O=C(NCc1nnc2n1CCC2)NC12CC3CC(CC(C3)C1)C2 +CCc1nc2cc(NC(=O)N(CCOC)Cc3ccco3)ccc2o1 +COC(=O)c1ccc(C(=O)Nc2ccccc2-c2ccccc2)cn1 +CC(=O)Nc1ccc(NCCC(O)c2cccc(N)c2)cc1 +Cc1cc(Br)ccc1C(=O)NCC(O)c1ccccc1 +O=C(NCC1COCCO1)c1cc(COc2cccc(F)c2)[nH]n1 +COc1ccccc1N1CCN(CCC(F)(F)C(F)F)CC1=O +NC(=O)COC(=O)c1ccc(Oc2cccnc2)cc1 +O=C(NCC1CCCO1)c1ccc(Cn2cccn2)cc1 +Cc1cc(S(=O)(=O)NCCO)c(C)cc1Cl +Cc1oc(-c2ccccc2)nc1CC(=O)NC1CCOc2ccccc21 +COc1ccc(NC(=O)Cc2noc(-c3ccccc3OC)n2)cc1 +Cc1cc(C)n2ncc(C(=O)NC3C4CC5CC(C4)CC3C5)c2n1 +O=C(NCCc1ccccc1)c1ccc2c(c1)OCO2 +CC(C#N)OC(=O)Cn1ccc2ccc(Cl)cc21 +CCCN(CC1CC1)C(=O)c1cc(OC)ccc1N +Cc1ccccc1CCC(=O)N(C)c1ccccc1S(C)(=O)=O +Fc1cccc(CN2CCN(c3ncccn3)CC2)c1F +CCOc1ccc(NC(=O)CNC(=O)c2cc(F)cc(F)c2)cc1C +NS(=O)(=O)c1ccc(NC(=O)N2CCCCC2)cc1 +CC(OC(=O)c1ccoc1)C(=O)Nc1ccc(SC(F)F)cc1 +O=C1NCCc2ccc(S(=O)(=O)Nc3cn[nH]c3)cc21 +CC(C)Oc1ccc(C(=O)Nc2cnn(C3CCOCC3)c2)cc1 +CC(=O)c1c(C)nn(S(=O)(=O)c2ccc(C)cc2C)c1C +CC1CN(S(=O)(=O)c2ccc3oc(=O)ccc3c2)CCO1 +O=C(CCCc1cc(F)ccc1F)NCc1ncc[nH]1 +CC1CCN(C(=O)CC2CSc3nc(C(C)(C)C)cc(=O)n32)CC1 +COc1cc2[nH]c(=O)c(C(C)O)cc2c(OC)c1OC +CCNc1nc(C(N)=O)c(NC(=O)c2ccccc2Cl)s1 +Cc1ccc(C)c(C(C)Nc2ccc(C(N)=O)cc2)c1 +CN(C)S(=O)(=O)N1CCN(c2ncnc3ccccc23)CC1 +C#CCN(Cc1ccco1)S(=O)(=O)c1cn[nH]c1 +O=C(NCc1ccc(F)cc1)NCC1(N2CCOCC2)CCCCC1 +O=C(Cn1cnnn1)Nc1ccccc1Oc1ccccc1 +COC(=O)Nc1cccc(NC(=O)NC(C)c2ccccc2)c1 +Cc1cc(C)n(Cc2ccc(C(=O)N(C)CC3CC3)o2)n1 +CCc1nnc(SCC(=O)NC2CCCCC2)n1CC +COc1ccccc1OCC(=O)Nc1cc(Cl)ccc1F +O=C1CC(C(=O)N2CCCC2)Cc2ccc(F)cc21 +NC(=O)C(NCc1cc(F)c(F)c(F)c1)c1ccccc1 +Cc1ccc2c(c1)-c1oc(=O)c(C(N)=O)cc1C(C)O2 +Cc1noc(C)c1N(C)C(=O)NC1CCCC(C(=O)NC(C)C)C1 +CC(=O)N1CCC2(CCCN2c2nncs2)CC1 +C#CCOc1c(OC)cc(Br)cc1OC +Cc1ccccc1C1CC(C)N(C(=O)c2nccnc2C(N)=O)C1 +Cc1ccn(-c2cccc(C(=O)N3CCN(CC(C)O)CC3)c2)n1 +COCCN1CC2(CCCN(C(=O)CC3CCCC3)C2)CCC1=O +CC1CN(Cc2cc(F)c(F)cc2F)C(C)CO1 +CC(NC(=O)c1ccco1)C(=O)OCc1cccc(Cl)c1 +CCCS(=O)(=O)NCc1cccc(Cn2ccnc2)c1 +Cc1ccc2[nH]c(=O)c(CCC(=O)N3CCCC3)cc2c1 +CCCCN(Cc1ccccc1F)C(=O)c1cnc(C)cn1 +CCn1cc(C(=O)NCC2CCOC2)c2ccccc21 +CCN(CC(C)C#N)C(=O)C1CCN(c2nccc(OC)n2)CC1 +NC(=O)C1Cc2ccccc2CN1CCOc1ccccc1 +Cc1noc(C2CCN(C(=O)c3csnn3)CC2)n1 +CCOc1cc(C)ccc1S(=O)(=O)N1CCCCC1 +COc1ccccc1CC(=O)Nc1ccc(C)cc1OC +N#Cc1ccccc1CNCc1cc(F)ccc1Br +COC(=O)NCC(=O)NC(C)Cc1c(Cl)cccc1Cl +CC(Sc1nncs1)C(=O)NCCc1cccs1 +COc1ccccc1OCCN(C)C(=O)Nc1cnn(C)c1 +Cn1nc(C(C)(C)C)cc(C(N)c2cccs2)c1=O +Nc1cc(N)nc(SCCCCSc2nc(N)cc(N)n2)n1 +CCOc1ccccc1NC(=O)c1sccc1C +O=C(c1scc2c1OCCO2)N1CCOCC(O)C1 +COc1cc(Br)c(NC(=O)C2CC=CCC2)cc1OC +COCCOc1ccc(C2(C)Nc3ccccc3C(=O)N2C)cc1 +CNC(=O)c1ccc(NC(=O)COc2cc(C)ccc2C)cc1 +CC(O)(CNC(=O)C1COc2ccccc21)c1ccc(F)cc1 +Cc1cc(C)nc(SCNC(=O)c2ccc(F)cc2)n1 +O=C(CC1(O)CCCC1)Nc1ccc(OCc2cccnc2)cc1 +CC(CC(=O)Nc1ccc(N2CCOCC2)nc1)c1ccccc1 +CC(C)c1ccc(S(=O)(=O)N(C)CC(N)=O)cc1 +CCOc1ccccc1CN(C)C(=O)Nc1c(C)cccc1C +CCc1noc(C2CCCN(S(=O)(=O)c3ccccc3)C2)n1 +Cc1cc(-c2nn3c(-c4ccc(Cl)cc4)nnc3s2)n[nH]1 +CCc1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)cc1 +CCN(CC)C(=O)C1CCCN1C(=O)c1cc(F)cc(F)c1 +CCc1ccc(N2CC(C(=O)N3CCCC(C)C3)CC2=O)cc1 +CC(NC(=O)c1ccc(Br)cc1O)C(=O)N(C)C +CCCOc1cccc(C(=O)Nc2cnn(C)c2)c1 +COc1ccccc1OCCNC(=O)c1cc(-c2ccccc2)on1 +Cc1c(C(N)=O)nnn1CC(=O)NCc1ccco1 +Cc1cc(C(=O)NCC2(O)CCc3ccccc32)c(C)o1 +Cc1cc(C2CCN(c3ncnc4sc5c(c34)CCC5)CC2)[nH]n1 +CCC1CCCN(C(=O)CCc2nc3ccccc3c(=O)[nH]2)C1 +COc1cccc(OCC(=O)NCC(C)(C)C(N)=O)c1 +CCOC(=O)c1c(NC(=O)C(C)(C)C)sc(C(C)=O)c1C +Cn1cc(NC(=O)c2cccc3cc[nH]c23)cc(Br)c1=O +CCN(CC)C(=O)CN1CCN(C(=O)c2ccc(C)c(C)c2O)CC1 +Cc1cccc(C)c1OCC(C)NC(=O)NC1CCC(O)CC1 +O=C(CN1CCOCC1)Nc1ccc(C(=O)N2CCCCCC2)cc1 +Cc1ccccc1C1CCCN1C(=O)C1CC(=O)N(C2CCCC2)C1 +COCCCn1c2c(cc(C#N)c1=O)CN(C)CC2 +Cn1cc(NC(=O)c2n[nH]c3ccccc23)cc(Br)c1=O +O=C(Nc1nc(-c2ccccc2)cs1)c1cccc2cn[nH]c12 +O=C(NCCCn1ncc2c(Cl)cccc21)C1CCCO1 +Cc1cc(C)n(-c2ncnc3c2cnn3-c2ccccc2)n1 +CCOC(=O)c1ccc(COc2ccccc2F)o1 +COC(=O)c1cc(F)ccc1Cn1cnc2sccc2c1=O +Cc1cc(N)ccc1S(=O)(=O)Nc1ccc(Br)cc1 +Cc1cc(NC(=O)C2CC2c2ccccc2C)[nH]n1 +CC(C)(C)C(O)CN1CCN(C(=O)c2cnc[nH]2)CC1 +COc1ccc(NC(C)=O)cc1NC(=O)CCc1ccccc1F +COc1ccc2c(c1)CCCC2CC(=O)NCCc1nc(C)cs1 +Cn1c(SCC(=O)NCC(F)(F)F)nnc1-c1ccccc1F +COC1(CNC(=O)NCCc2ccc(C)nc2)CCC1 +CCC1Oc2ccc(C(C)C)cc2N(CCC#N)C1=O +COc1ccc(OC)c(NC(=O)Nc2c[nH]c(=O)[nH]c2=O)c1 +O=C(Nc1cnn(CC2CCCO2)c1)C1COc2ccc(F)cc2C1 +CC(OC(=O)c1ccccc1O)C(=O)NC(C)(C)C +CCOC(=O)c1noc(C)c1COc1ccccc1Cl +CCC(C)(NC(=O)Nc1nncs1)c1ccccc1 +CC(Nc1ncccc1S(N)(=O)=O)c1ccccc1C(F)(F)F +CCNC(=O)C1CCN(C(=O)NCc2ccc(C)c(F)c2)CC1 +Cc1c(C(=O)NCc2cscn2)oc2c(Cl)cccc12 +N#CC(c1ccc(Br)cc1)c1ccccn1 +CC(NC(=O)c1nc[nH]n1)c1ccc(-c2ccccc2)cc1 +O=C(Cn1ncc(N2CCCCC2)cc1=O)NCC1CCCOC1 +CC(C)(C)Oc1cc(S(N)(=O)=O)c(OC2CC2)cn1 +CC1CCC(NC(=O)N2CCC(c3nnc4ccccn34)CC2)CC1 +O=C(COc1ccc(Cl)cc1)N1CCC(Oc2cnccn2)CC1 +COc1ccc(C(O)CCC(=O)N2CCCCC2)cc1C +CC(=O)c1csc(NC(=O)C2COc3ccccc3O2)n1 +COc1cc(CNCC(C)(O)c2ccsc2)cc2c1OCCO2 +Cc1ncsc1C(=O)N1CCCN(c2cccc(F)c2C#N)CC1 +CCOC(=O)C1=C(CN2CCC3CCCCC3C2)NC(=O)NC1 +CS(=O)(=O)NCC1CCCN(C(=O)NC2CCCCC2)C1 +CN(Cc1ccc(N)cc1Cl)Cc1nccn1C +O=C(CCn1ccnn1)NC1(c2ccc(Br)cc2)CC1 +O=C(Cn1ccc2ccccc21)NCCCn1ncccc1=O +N#Cc1ccc(CNCCc2c[nH]c3ccccc23)cc1 +CNC(=O)c1nnc2ccc(-c3ccccc3)nn12 +CN(Cc1ccc(S(C)=O)cc1)Cc1cnc2cnccn12 +Cc1cc(C)nc(C(C#N)C(=O)CCc2cccc(Cl)c2)n1 +CCN(CC)C(=O)C1CCN(C(=O)C(C)OCC2CC2)CC1 +COCCNC(=O)NC1CCCc2[nH]c(=O)ccc21 +CC(C)CC(=O)Nc1ccc(NC(=O)N2CCCC(CO)C2)cc1 +CNC(=O)CNC(=O)c1ccc2c3c(cccc13)CC2 +CC(C)(C)c1ncc2c(n1)CN(C(=O)CSc1ccccc1)C2 +CCC(C)C(=O)NCc1ccnc(-n2cccn2)c1 +Fc1ccc(CNc2nnc3n2CCCCC3)cc1 +CC(C)N(C(=O)CSc1nncn1C)c1ccccc1 +Cc1ccc(CCC(=O)Nc2cc(C)ccn2)cc1 +O=C(Nc1cccc(F)c1)c1cccc(NC(=O)c2csnn2)c1 +O=C(NCCc1cnn(-c2ccccc2)c1)c1ccnc2ccccc12 +COC(=O)c1cccc(NC(=O)N(C)Cc2ccc(C)s2)c1 +O=C(Nc1ccc2[nH]c(C(F)(F)F)nc2c1)c1ccco1 +Cc1ccc(C)c(NC(=O)C(O)c2ccc(F)c(C)c2)c1 +CC(=O)Oc1ccccc1C(=O)N1CCC(C)CC1 +c1ccc(C2(c3nn(-c4ccccn4)c4c3CNCC4)CC2)cc1 +O=S1(=O)N=C(N2CCOC(c3ccc(F)cc3)C2)c2ccccc21 +N#CCSc1nc(-c2ccc(Br)cc2)n[nH]1 +Nc1ccn(CC(=O)OCc2cc(Br)ccc2F)n1 +Cc1cc(C)c(-n2nc(C)c(CO)c2C)c(Cl)c1 +Cc1ccc(-n2ccc(=O)c(C(=O)Nc3nnc(C)s3)n2)cc1 +Nc1cccnc1NCCCNC(=O)Cc1cccs1 +CC(=O)Nc1nc(C(=O)Oc2ccc(C)cc2)cs1 +Cc1noc(NC(=O)CCCOc2ccc(S(C)(=O)=O)cc2)n1 +COc1ccc2[nH]cc(CC(=O)NC(C)CO)c2c1 +O=C(NC1CCCCCC1)c1cc2cc(F)ccc2[nH]1 +CC(C)(C)CC(=O)NCc1cccc(OCc2ccccn2)c1 +O=C(NCc1cccc(F)c1)C1CCN(c2cn[nH]c(=O)c2)CC1 +COc1c(F)cc(NC(=O)C2CC=CC2)cc1F +COc1ccc2c(c1)CCCC2CC(=O)N1CCCCC1CCO +Cc1noc(COCC(=O)NCc2nc3ccccc3n2C)n1 +O=C(CC1C(=O)Nc2ccccc2S1=O)Nc1ccccc1 +Cc1ccc(-n2ncc3c(Nc4ccc(O)cc4)ncnc32)cc1 +CCn1nc(C)cc1C(=O)N1CCC(=O)N(CC(C)C)CC1 +CCc1oc2ccccc2c1CN(C)C(=O)C1CCCN1C(C)=O +CSc1nc2nnc(C(=O)N3CCCCC3)c(C)n2n1 +Cc1noc(C(C)OC(=O)c2ccc(C(F)(F)F)cc2)n1 +CCOC(=O)C1CCN(C(=O)c2cn3c(n2)COCC3)CC1 +CN(CC1CCCO1)C(=O)NCCCc1ccccc1 +NC(=O)c1ccccc1NC(=O)CNc1cccc(C(F)(F)F)c1 +CN(Cc1cnn(C)c1)C(=O)c1cc(Cl)c[nH]1 +N#CC1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1 +O=C(c1ccc(OCC(F)F)nc1)N1CCCC(n2cccn2)C1 +CC(C)(C)C1CCC(C(=O)Nc2cc(-c3ccncc3)n[nH]2)CC1 +CSc1ccc2nc(NC(=O)c3cc(C)oc3C)sc2c1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCOc2cc(F)ccc21 +O=C(CO)N1CCN(C(=O)Cn2ccc(=O)c3ccccc32)CC1 +CC(C)C(C)NC(=O)c1cccc(C(=O)NC(C)C(C)C)c1 +CC(=O)c1c[nH]c(C(=O)NCCc2coc(-c3ccc(F)cc3)n2)c1 +CCC(CC)n1ncc(C(=O)N2CCc3cc(F)ccc3C2)c1C +C=CCn1c(SC2CC(C)OC2=O)nnc1C1CC1 +Cc1ccc(-c2cc(N)c(=O)n(CC(=O)NCc3ccco3)n2)o1 +Cc1cc(OCC(=O)Nc2ccc(-c3ncc(C(C)C)o3)cc2)no1 +CCCCn1c(N)c(N(CC)Cc2ccccc2C#N)c(=O)[nH]c1=O +C#CCNC(=O)C(NC(=O)C1CCCCC1)C(C)C +O=C(c1ccc(-n2ccnn2)cc1)N1CCCCCC1c1ccncc1 +CN1C(=O)C2(CCN(Cc3cccs3)CC2)C1c1ccccc1 +Cc1c(N)c(Br)c(C)c2cnccc12 +Cc1cc(CNc2cc(C3CCN3S(C)(=O)=O)nc(C)n2)on1 +COCCn1c(SCc2ccccc2)nnc1-c1ccncc1 +O=C(Nc1cccnc1Oc1ccccc1)NC1CCCCNC1=O +Cc1noc(CCC(=O)Nc2cccc(C(=O)N3CCOCC3)c2)n1 +CC(Oc1cccc(-c2ccc(C(=O)N(C)C)cc2)c1)C(N)=O +CCNS(=O)(=O)c1ccc(CC(=O)COC)cc1 +COCCC(=O)NC1(c2ccc(F)cc2F)CCOCC1 +CCc1cnc(N2CC3CC(C(=O)N4CCN(C)CC4)C(C2)O3)nc1 +Cc1cnc(NC(=O)C2CC(=O)N(C)C2c2cccs2)s1 +O=C(CCc1ccsc1)Nc1ccccc1-n1cccn1 +CNC(=O)NC(C)(C)C(=O)N(C)Cc1cnc(C)s1 +Cc1cc(C)c(C(=O)CCC(=O)N2CCOCC2)c(C)c1 +Cc1ccc(CC(=O)NC(C)c2ccc(C(F)(F)F)cc2)cn1 +CS(=O)(=O)c1ccc(C(=O)Nc2sccc2C(N)=O)cc1 +Cc1ccc(S(=O)(=O)N(CCC#N)C2CCOCC2)c(Cl)c1 +CC(C)(C)OC(=O)N1CCCC(S(=O)c2ncccn2)C1 +COCCN(C)C(=O)Nc1cccc2c1OCCO2 +O=C(CSc1ccccc1)NCc1ccccc1F +O=C(NC1CCc2c(O)cccc21)c1cccc(-n2cnnn2)c1 +Cc1cc(C)n(CCCNC(=O)c2cnc3sccn3c2=O)n1 +C=CCNC(=O)CSc1ccc(-c2ccc(C)cc2)nn1 +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)Nc1nc(-c2ccco2)cs1 +CC(Nc1ncnc2sccc12)c1ccc2[nH]c(=O)[nH]c2c1 +COC(=O)C(NC(=O)Cc1cccc(F)c1)C(C)(C)C +Cc1nn(CC(=O)N(C)C(C)C2CC2)c(C)c1N +Cc1ccc(C(=O)COc2ccccc2C(N)=O)s1 +CCC(C)n1cccc(-c2nnc(NC)s2)c1=O +Cn1nc(C2CCN(C(=O)c3ccncc3)CC2)c2cccnc21 +CC(C)C(NCc1nnnn1-c1ccccc1)c1cccs1 +Cc1cccc(Nc2nnc(SC(C)C(=O)N(C)C)s2)c1C +COc1ccc(CNC(=O)Cn2ccc(-c3ccccc3)n2)cc1 +O=C(Nc1nnc(Cc2ccccc2)o1)c1ccc2c(c1)OCO2 +CC(=O)NC(C(=O)OC1CCCC(C)C1)C(C)C +CC1CCCN(C(=O)Nc2ccnc(Oc3ccccc3)c2)C1CO +COc1ccccc1C(C#N)NC(=O)c1cnc(-c2ccccc2)nc1 +CCN(c1cccc(C)c1)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +CCOCC1CCCN(C(=O)CCn2cnc3sccc3c2=O)C1 +Cc1cccc(Nc2ncnc(-n3ccnc3)c2N)c1C +COc1ccc2c(c1)nc(-c1ccc(N)cc1)n2CC#N +Cc1ccccc1CSc1nnc(C)c(=O)n1N +CC(C)Oc1ccc(Cl)cc1C(=O)Nc1cnn(C)c1 +CCNC(=O)Nc1cccc(NC(=O)Cc2ccc(OC)c(F)c2)c1 +Cc1n[nH]c(SCC(=O)N2c3ccccc3CC2C)n1 +Nc1cc(-c2c[nH]nc2-c2cccc(F)c2)ccn1 +CCCN(C)C(=O)CCNS(=O)(=O)c1ccc(C)cc1 +CCc1nc(CC(=O)Nc2cc(C)nn2Cc2ccccc2)cs1 +CC(C)c1cc(C(=O)NCc2cccnc2-n2cncn2)n[nH]1 +N#Cc1ccc(Cl)cc1NC(=O)c1cc(Cl)ccn1 +CCC1CN(C(=O)c2cnn(C)c2)CCC(=O)N1Cc1ccccc1 +CCC(CO)NS(=O)(=O)c1ccc(Cl)cc1 +CCOCC1CN(Cc2ccsc2)Cc2cnn(C)c21 +COCCN(C)C(=O)c1nc2c(s1)CCCN2c1ccccc1 +COCc1cccc(C(=O)NC(C)c2ccc(C)o2)c1 +COc1cccc2c1Oc1nn(-c3ccccc3)c(N)c1C2 +CCOC(=O)c1nc2ccc(Br)cn2c1N +CC(C)NC(=O)COC(=O)C1CCCC(C(F)(F)F)C1 +O=C(CN1CCCCC1=O)NCc1cccc2ccccc12 +CC1CCN(C(=O)Nc2cccc(N3CCCC3=O)c2)CC1 +C#Cc1cccc(NCC(=O)N(Cc2ccccc2)C2CC2)c1 +N#CCCN(Cc1cccnc1)C(=O)c1ccccc1Cl +COc1cc(Cl)c(NC(=O)Cc2ccccc2)cc1OC +CCCNC(=O)CN(C)c1nn2c(=O)cc(CCC)nc2s1 +COc1cc(OC)cc(C(=O)NCC(=O)Nc2ccc(Cl)cc2)c1 +CN(C(=O)c1ccc2ccccc2n1)c1ccc(F)c(F)c1 +COC(C)C(=O)Nc1cc(NC(=O)Nc2ccccc2)ccc1C +CCOc1ccc(Oc2ncc(N)cc2C#N)cc1 +CC1CCCC1NC(=O)c1ccc2c(c1)OCCCO2 +C=CCN(C(=O)C1CNC(=O)N1)c1nc2c(s1)CCCC2 +C=CCNS(=O)(=O)c1ccc(C(=O)Nc2nccs2)cc1 +Cc1ccc(OCC(=O)N(C)Cc2ccc(C)o2)cc1 +O=C(CCn1cncn1)N(C1CC1)C1CCCc2ccccc21 +COc1ccnc(NC(=O)c2ccc(-n3cnc4ccccc43)cc2)c1 +CC(C)CC(C)N(C)C(=O)CSc1nnnn1C +CCC1CCCCN1C(=O)C(C)Sc1nnc(-c2ccncc2)o1 +COCC(COC)Oc1c(F)c(F)nc(F)c1F +COc1cc(C)c(S(=O)(=O)N2CCOC(C)(C)C2)cc1C +COC(=O)c1cccc(NC(=O)Cc2cccc(OC)c2)c1 +O=C1CCCc2[nH]c(=O)c(C(=O)N=c3[nH]c4ccccc4[nH]3)cc21 +Cc1cc(C(=O)NCCNC(=O)c2ccc(F)cc2)c(C)n1C(C)C +Cc1nc(C2CCCN(C(=O)c3ccc4c(c3)CCCC4)C2)no1 +CCOC(=O)C(C)(C)NC(=O)c1c[nH]c2cccc(F)c12 +CC(=O)Nc1ccc(CCNCc2sc(C)nc2C)cc1 +Cc1nc2sccn2c1CN1CCN(c2cnn(C)c(=O)c2)CC1 +Cc1ccccc1OCC(=O)Nc1cccc(CCC(=O)N(C)C)c1 +CC(=O)c1ccc(C(F)(F)F)cc1S(C)=O +COc1cc(-c2nc(CN)cc(=O)[nH]2)ccc1OCC(C)C +O=C(Oc1ccccc1F)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CCC(C)(C)C(=O)NCC(c1ccc(OC)cc1)N1CCOCC1 +Cc1nc(-c2cccc(NC(=O)CC3C=CCC3)c2)cs1 +Cc1ccc(CNC(=O)c2cc(C(C)C)nc(N(C)C)n2)o1 +CC(=O)c1ncc(C(F)(F)F)cc1Br +CCC(C)N(C)C(=O)Nc1ccc2c(c1)OCO2 +CC1Cc2ccccc2N1C(=O)Cn1cnc2ccccc21 +O=C(Nc1ccc2[nH]ccc2c1)N(CCO)C1CCCCC1 +Cc1ccc(S(=O)(=O)NCC(=O)NCCc2ccccc2)cc1 +COc1ccc(C(=O)NCCNC(=O)Nc2c(F)cccc2F)cc1 +Cn1cc(NC(=O)CCCc2nnc3ccccn23)cn1 +Cc1nc(CN(C)C(=O)c2scnc2C2CC2)cs1 +COc1cc(OC)c(NC(=O)NCc2cc(C(C)C)no2)cc1F +CCCc1n[nH]c(C2CN(C(=O)c3cc(COC)oc3C)CCO2)n1 +CCc1nc(COC(=O)Cn2nc3n(c2=O)CCCCC3)cs1 +O=C(Nc1cccc(Cn2ccnc2)c1)c1cc(F)cc(F)c1 +COCCn1ccc(NCc2cc3cccc(OC)c3o2)n1 +O=C(OCC#Cc1ccccc1)c1ccc(-n2cncn2)cc1 +Cn1ccc(NC(=O)C2(c3ccc(Cl)cc3)CCCC2)n1 +COC(=O)c1ccc(C(N)c2nc3c(s2)CCC3)cc1 +CCCC1CN(C(=O)c2ccnc(N(C)C)c2)CCO1 +Cc1nc(SCC(=O)NCC(=O)N2CCCC2)c(C#N)c(C)c1C +Cc1csc(=O)n1CCC(=O)NCC1(O)CCCc2ccccc21 +COCCN(C(=O)c1ccnc(F)c1)C(C)COC +OCc1ccc(C2NCCc3ccc(F)cc32)cc1 +CC1CCc2c(sc(NC(=O)CCN3CCOC(C)C3)c2C#N)C1 +CC(=O)N(CCc1ccccc1)CC(=O)NC(C)C1CCCO1 +NC(=O)Cc1ccc(NC(=O)Nc2cccs2)cc1 +CCOC(=O)CN(CC)S(=O)(=O)c1cn[nH]c1C +Cc1cccc(OC(C)C(=O)NCc2ccnc(OC3CCC3)c2)c1 +Nc1nonc1-c1nc2ccccc2n1Cc1ccccc1F +CCOC(=O)c1ccc(NC(=O)c2ccc(C)c(NC(C)=O)c2)cc1 +COc1ccc(CNC(=O)c2cc(C)sc2C)cc1O +CC1(COC(=O)c2cccc(-c3ccoc3)c2)COC1 +CCOC(=O)C(C)(O)CNC(=O)c1cc(F)c(C)cc1F +CCSc1cccc(NC(=O)NC(C)Cc2c(C)noc2C)c1 +Cc1ncsc1CN1CCN(Cc2cccc(O)c2)CC1 +CC(C)n1ncc2c1N=C(O)CC2c1cccc(O)c1 +N#Cc1ccccc1COC(=O)CNC(=O)c1ccccc1 +CCCCn1c(=O)[nH]c(=O)c2c1nc(CSc1nccn1C)n2C +Nc1ncccc1C(=O)NCCc1ccc(F)cc1 +COc1cccc(CNC(=O)Nc2ccc(C(C)=O)c(C)c2)n1 +O=C(NC1CCCC1)c1coc(NC(=O)c2cccs2)n1 +Cc1cc(NC(=O)C2CCCN2C(=O)c2ccco2)n(C)n1 +COCCOc1ccc(CNc2cnc3ccccc3n2)cn1 +Cc1nn(C)c(C)c1-c1nn2c(-c3ccc(F)cc3)nnc2s1 +O=C1C2CCC(CN(Cc3cccc(F)c3F)C2)N1CC1CCC1 +O=C1NC2(CCN(C(=O)c3cccc(F)c3)CC2)Nc2ccccc21 +CC(C)c1ccccc1OCCC(C#N)C(=O)N1CCCC1 +CCC(C)NS(=O)(=O)c1cc(C(=O)C(C)C)ccc1C +O=C(Nc1ccnc2ccccc12)c1c(F)cccc1F +COc1cc(C(C)=O)ccc1OC(=O)Cn1cc(C)c2ccccc21 +CCn1ncc(C(=O)NCc2ccccc2Cl)c1C +FC(F)(F)c1ccccc1-n1nc(C2CC2)nc1C1CCOC1 +NC(=O)N1CCCC(C(=O)Nc2cccc(OC(F)(F)F)c2)C1 +COc1cc(C)c(C(=O)Nc2cccc3cccnc23)cc1OC +COc1ccc(-c2nc(CSc3nnnn3C3CC3)cs2)cc1 +CCc1ccc(NC(=O)NCC(=O)Nc2c(C)cccc2C)cc1 +Cc1noc(-c2cccnc2)c1C(=O)N1Cc2ccccc2C1 +CCc1ccccc1NC(=O)Cn1c(C)nc2c(c1=O)CCCC2 +O=C1COc2cc(NC(=O)NC3CCCCC3O)c(Cl)cc2N1 +CC1(C)CC(=O)N(CCCC(=O)Nc2nncs2)c2ccccc21 +Nc1cc(Cc2nc(-c3ccccc3)cs2)ccc1OCCO +O=C(Cn1ccc2ccccc21)NC1CCN(c2nccs2)CC1 +FC(F)(F)CN1CCC(CNc2ccc(Cl)cn2)C1 +CC(=O)NCc1ccc(C(=O)COC(=O)C2CC=CCC2)s1 +Cc1ccccc1CNC(=O)c1nn(C)c2ccccc12 +COc1ccc(C(O)C(C)NC(=O)c2ccc(OC)cc2C)cc1 +CC(C)Cn1ccc2cc(NC(=O)CCCC(=O)N(C)C)ccc21 +CC1=C(C(=O)Nc2ccccc2)C(c2cnn(C)c2C)n2ncnc2N1 +CS(=O)(=O)N1CCC(C(=O)N2CC(=O)Nc3ccccc32)CC1 +CCn1ccc(C(=O)N=c2sc3cc(OC)c(OC)cc3n2C)n1 +CCCN(CCC)C(=O)c1ccc(-c2cccnc2)cc1 +COc1ccccc1-c1ccc(=O)n(CC(=O)N2CCC(C)CC2)n1 +CCn1c(SCc2ccc(OC)cc2)nnc1-c1ccncc1 +CC(C)(C)c1ccc(OCCNC(=O)c2cnccn2)cc1 +O=C(NCc1ccc(-n2cccn2)cc1)c1ccc(Cl)cc1F +Cc1ccc2c(=O)c(C(=O)c3ccc(F)cc3)cn(CC(N)=O)c2n1 +O=c1[nH]ncc(N2CCN(c3ccc(F)cc3)CC2)c1Cl +CCC(C)NC(=O)c1ccc(NC(=O)Cc2ccccc2F)cc1 +CC1(C(=O)Nc2cc(F)cc(F)c2)Cc2ccccc2C(=O)O1 +Cc1ccc(S(=O)(=O)NCCC(=O)N(C)C)cc1C(F)(F)F +CCN(Cc1cccc(Cl)c1)C(=O)NCCNC(C)=O +Cc1noc(C)c1S(=O)(=O)Nc1cc2c3c(c1)CC(=O)N3CCC2 +CCC1CCCCN1C(=O)c1cc(N)ccc1Cl +CC(C#N)CNC(=O)c1cccc(COc2cccc(C#N)c2)c1 +COc1cc(C(=O)NCC2C(=O)N=C(C)C=C2C)cc(Cl)c1O +Cc1cc(C)n2nc(CC(=O)N3CCc4ccccc4C3)nc2n1 +COCCNC(=O)c1ccc(Cl)c(NC(=O)NC2CCCC2)c1 +CCc1n[nH]c(SCC(=O)Nc2ccccc2)n1 +COc1ccc(OC)c(-c2nnc(NC(=O)c3cccs3)o2)c1 +OCCC1CN(Cc2cccnc2)CCN1Cc1cccs1 +N#CC(NC(=O)CCc1cccnc1)c1ccc(Cl)c(Cl)c1 +COc1ncccc1NC(=O)NCc1cccc(N2CCCC2=O)c1 +CCCOC(=O)CSc1nc2ccccc2n1C +CC(=O)N1CCC2(CC1)CN(C(C)=O)CC21CCNC1=O +CN(Cc1csc(-c2ccccc2)n1)C(=O)Cn1cncn1 +Cn1c(=O)oc2cc(NS(=O)(=O)NCc3ccccc3)ccc21 +CN(CCOc1ccccc1F)C(=O)Cn1cc(Cl)cn1 +O=C(Nc1ccncc1)C1CC(=O)N(c2ccc(F)c(Cl)c2)C1 +Cc1nnc(Cn2nnnc2Cc2ccc(Br)cc2)o1 +Cc1nn(C)c(C)c1CNC(=O)c1cc(Cl)ccc1Cl +CCC(C)C(NC(=O)COC)c1nc2cccnc2n1C(C)C +CC(NC(=O)N(C)CC1CCCO1)c1ccccc1 +CCCOc1ccc(Cl)cc1NC(=O)c1cc(C(N)=O)cs1 +CCN(CC)S(=O)(=O)c1cc(N)c2c(c1)nc(C)n2C +COC(C)(C)C(=O)NCc1cccnc1Oc1ccc(F)cc1F +O=C(c1ccc(F)c(F)c1)N(Cc1ccc(F)cc1)C1CC1 +O=C(NCc1ccccc1Cl)Nc1ccccc1 +Nc1cc(F)cc2c(NCCO)ncc(Br)c12 +COc1ccccc1NC(=O)C(O)c1ccccc1 +Cc1ccc(NC(=O)CNC(=O)c2cccc(Cl)c2)c(O)c1 +NS(=O)(=O)c1ccc(OCCSc2ncccn2)cc1 +C=CCN(Cc1cccs1)C(=O)COc1ccc2c(c1)OCO2 +CCOC(=O)Cc1nc2c(Br)cccn2c1N +CCCOCc1nc2c([nH]1)CC(c1ccc(Cl)cc1)CNC2=O +O=C(NC1CCN(C(=O)OCc2ccccc2)C1)C1CCOCC1 +Nc1ccc(S(=O)(=O)N2CCc3sccc3C2)cn1 +O=C(c1cc(=O)nc2cccnn12)N1CCc2ccccc2C1 +Cc1cc(C)c(CNC(=O)c2ccc(C(F)(F)F)cn2)c(=O)[nH]1 +C=CCN1CCN(S(=O)(=O)c2ccccc2)CC1 +Cc1ccc(NC(=O)NCc2cccnc2-n2cncn2)s1 +Cc1ncn(CC(O)CN2CC(C)OC(C)C2)c(=O)c1C +O=c1c2ccsc2ncn1Cc1ccc2nonc2c1 +O=c1[nH]c2cc(C(F)(F)F)ccc2n1-c1ccccc1 +Cc1cc(OC(=O)Cc2c(C)nn(C)c2C)ccc1C(C)C +COCC(O)CN(C)C(=O)c1ccc(C(C)C)cc1 +COc1ccccc1NCCCN1CCOCC1 +CCC(=O)N(C)CCc1noc(-c2ccccc2Cl)n1 +Nc1nc(-c2cccc(Cl)c2)ncc1C(=O)N1CCCC1 +CSc1nc2nc(C)c(CC(=O)Nc3cc[nH]n3)c(C)n2n1 +CC(O)(CNC(=O)c1ccc(F)c(F)c1)c1ccc2c(c1)OCO2 +Cc1c(C(=O)NC(C)c2ccccc2)ccc2cncn12 +Cc1noc(C)c1CC(=O)N1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1ccc(C(=O)Nc2ccc(C(=O)NC3CC3)cc2)c(C)c1 +Cc1occc1C(=O)NCC(=O)Nc1ccc(F)c(C(N)=O)c1 +CC(Cn1cccn1)OC(=O)c1cc(C(N)=O)cn1C +FC(F)COc1ccccc1NCc1ccncc1 +CC(=O)Nc1cccc(Oc2nc3cc(C)nn3c3ccccc23)c1 +Nc1ccc(NC(=O)C(c2ccccc2)c2ccccc2)cn1 +Cn1c(=O)c2c(nc3n2CCCN3c2ccc(Cl)cc2)n(C)c1=O +CCC1Oc2ccc(N)cc2N(CC(=O)N2CCCC2)C1=O +O=C(c1ccnc(OC2CCC2)c1)N1CCOC(c2nccs2)C1 +O=C(c1cccc2[nH]ncc12)N1CCCC1C1CCCC1 +CC(C)(C)c1nnc(NC(=O)N2CCOC(c3ccccc3)C2)s1 +Cc1cccc(NC(=O)c2ccc(-c3nc(C)no3)cc2)n1 +CCOc1nc(C)ccc1-c1noc(-c2cc(OC)cc(OC)c2)n1 +O=C(Cn1cnc2ccccc2c1=O)OCCCc1ccncc1 +CN(Cc1ccccn1)C(=O)c1ccc(OCC(N)=O)cc1 +Nc1oc(-c2ccccc2)cc1C(=O)c1cscn1 +CN(C)CC1NCCc2cc(O)c(OC(F)(F)F)cc21 +COCCN(C(=O)c1cccc(C)c1C)C(C)C(N)=O +CN(C)c1ncnc2c1CN(c1cnc3ccccc3n1)CC2 +COC(=O)C(Cc1cc(F)ccc1OC)NC(C)=O +CCn1ccc2cc(NC(=O)c3ccccn3)ccc21 +CCN(CC)C(=O)c1sc(C(N)COC)nc1C +Cc1ccc(NC(=O)CNS(C)(=O)=O)cc1F +CC(NC(=O)C(NC(=O)Cc1ccccc1)C(C)C)c1ccco1 +COc1ncccc1CN(C)C(=O)Cc1ccccc1 +CCCCN1CNc2c(c(=O)[nH]c(=O)n2-c2cccc(Cl)c2C)C1 +Cn1c(SCC(=O)Nc2ccncc2)nnc1-c1ccco1 +CC(C)C(=O)N1CCN(Cc2cc(=O)oc3cc(O)ccc23)CC1 +CN1C(=O)Cc2cc(S(=O)(=O)NCc3ccco3)ccc21 +NC(=O)CCN(C(=O)c1cnn(-c2ccccc2)n1)c1ccccc1 +O=C(c1ccc2[nH]cnc2c1)N1CCC2(C=Cc3ccccc3O2)CC1 +CC(=O)Nc1ccc(NCCOc2cccc(C)c2)cc1 +Cc1cccc(C)c1OCCNC(=O)c1scnc1C +Cc1ccc(C)c(OCC(=O)Nc2cccnc2-n2cccn2)c1 +COCCNC(=O)NC(C)C(OC)c1ccc(Cl)cc1 +Cn1nnnc1Sc1ncccc1C(=O)Oc1ccc(F)cc1 +CCCC(C)(NC(=O)c1cn(C)c2nc(C)ccc2c1=O)C(=O)OC +Cn1nc(C(=O)Nc2cnn(-c3ccccc3F)c2)ccc1=O +CC(C(=O)NCC1CCCO1)N1CCc2c(nc(C3CC3)n2C)C1 +O=C(c1ccoc1)N1CCC(C2CCN(c3ncccn3)CC2)C1 +COc1cc(NC(=O)c2cccc(N3CCCC3=O)c2)cc(OC)c1 +CC(=O)NC1CCCN(C(=O)CSc2nc(C)c(C)o2)C1 +CCN(Cc1cccc2c1OCO2)C(=O)CCCn1cncn1 +Cc1ccc(C(=O)Nc2nc(-c3ccccc3)c(C)s2)o1 +Cc1noc(CCC(=O)NCc2ccc(C(C)(C)C)cc2)n1 +CCNC(=O)CSc1nnc(-c2ccccc2C)o1 +CCOC(=O)Cc1ccccc1NC(=O)c1cccc2ccc(C)nc12 +Cc1cc(C)c(NC(=O)CSNC(=O)Nc2ccccc2)c(C)c1 +Nc1cc(F)cc2c1CCNC2c1cccc(O)c1 +Cc1ccc(C)c(S(=O)(=O)NCC2CCOC2)c1 +CCOCC1CCCN(S(=O)(=O)c2ccccc2F)C1 +Cc1ccc2nc(C(=O)N3CCNC(=O)C3CCO)cn2c1 +Cc1noc(C)c1CC(=O)Nc1cnc(C(C)(C)C)nc1 +CSc1ccc(Cl)cc1NC(=O)C1CCCN1C(=O)C(C)C +COc1ccnc2c(NC(=O)NCC(C)c3nccs3)cccc12 +O=S(=O)(CC1CC1(Cl)Cl)Nc1ccccc1 +c1cc(OCc2noc(-c3ccoc3)n2)cc(-n2cnnn2)c1 +O=S(=O)(c1ccccc1O)c1ccccc1O +CC(CNC(=O)CCCc1nc2ccccc2o1)N1CCOCC1 +O=C(Nc1ccccc1CN1CCOCC1)c1ccc2c(c1)CCO2 +Cc1cc(C)c2c(c1)S(=O)(=O)N(C)C(Cl)=N2 +CCCc1nc(CN2CCc3ccccc32)cs1 +COC(=O)c1ccc(NC(=O)COc2ccc(F)cc2)cc1 +CCN1CC(CN(C)C(=O)c2ccccc2O)Oc2ccccc21 +COc1ccc(C(=O)Nc2ccccc2OCC(C)C)nn1 +O=C(NCCCc1ccccc1)c1[nH]cc2c1CCC2 +COc1ccc(S(=O)(=O)N2C3CCC2CC(=O)NC3)cc1 +Cc1ccc(NC(=O)N2CCNC(=O)CC2)cc1Cl +Cn1ccnc1SCC(=O)c1ccc(F)cc1 +CCOc1ccc(C(=O)Nc2nc(C(C)=O)cs2)cc1 +O=C(Nc1ccc(C(=O)N2CCCCC2)nc1)c1cccc2cn[nH]c12 +CCC(C#N)NC(=O)C(C)Sc1ccc(OC)cc1 +CCC(C)NC(=O)C(C)NC(=O)C(C)c1cccs1 +CC(C)CNC(=O)COCc1cc(-c2ccc3c(c2)OCO3)on1 +NC(=O)Cc1ccccc1-c1nn2cnnc2s1 +CC(C)(C)c1nnc(CNc2ccc(Br)c(F)c2)o1 +Cc1ccccc1OCCCC(=O)N1CCCS1(=O)=O +COc1ccc(C(=O)Nc2cccc(CO)c2)cc1OC +CC(=O)Nc1ccc2nc(NC(=O)Cc3c(C)noc3C)sc2c1 +Cc1nn(C)cc1CN(C)C(=O)c1ccc(Cc2c(C)noc2C)o1 +CCSc1nnc2c(n1)OC(CC)Nc1ccccc1-2 +Nc1ccc(F)cc1NC(=O)Cn1cc(Br)cn1 +O=C(Nc1nccs1)C1CCCN1C(=O)c1scnc1C1CC1 +CC(C)CC(=O)Nc1nc(-c2ccccc2)ns1 +COc1c(F)cc(NC(=O)C(C)NC(N)=O)cc1F +COCc1c(C#N)nnn1-c1ccc(Cl)c(Cl)c1 +CN(C)C(=O)CCc1ccc(NC(=O)Nc2cccc(Cl)c2)cc1 +Cc1csc(CN(C)Cc2ccccc2N(C)C)n1 +FC(F)CN(Cc1ccccc1-n1cccn1)C1CC1 +O=C(NC1CC1)C1(c2cc(-c3ccc4c(c3)OCO4)on2)CC1 +NS(=O)(=O)c1ccc(NC(=O)N(Cc2ccccn2)C2CC2)cc1 +CCC(=O)N1CCC2(CC1)CC(Oc1ccccc1)CO2 +Cc1ccccc1OCc1ncc2c(n1)CCNC2 +Cc1cccc(OCC(=O)Nc2ccncc2Cl)c1C +CC(=O)N1CCN(C(=O)c2ccc3ccccc3c2O)CC1 +Cc1nnc2ccc(NC(=O)c3ccccc3)cn12 +CC(O)CC(C)CNC(=O)NCc1ccc(Cl)cc1Cl +Cc1cc(N)ccc1SCc1cc(=O)c(O)co1 +O=C(CN1CCc2ccc(Cl)cc2C1)NCC(=O)c1ccccc1 +COc1ccc(-c2csc(Nc3c(C)n[nH]c3C)n2)cc1 +CC(C)c1ccsc1C(=O)N1CCC(C(N)=O)C1 +CC(c1cccc(O)c1)N(C)C(=O)c1ccncc1F +O=S(=O)(Cc1ccc(F)c(Br)c1)c1ccc(O)cc1 +Cc1nc(N(C)Cc2cccc(C#N)c2)c2c3c(sc2n1)CCC3 +COc1ccc(S(=O)(=O)N2CCCC(O)C2)cc1F +C#Cc1cccc(NC(=O)CNC(=O)C(C)CC)c1 +COC(=O)c1cc(C(=O)N2CCc3ccc(C)cc32)ccn1 +CCCOC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)o1 +CNC(=O)NCC(=O)Nc1ccc(C)c(OCC(F)F)c1 +c1ccc(CCN2CCNC(c3nc4ccccc4[nH]3)C2)cc1 +CC(=O)Nc1ccc(NC(=O)Cc2ccc(F)cc2)cc1 +Cc1ncc(C(=O)NCc2ccccn2)c(C)c1N +N#Cc1ccc(F)c(CNC(=O)c2cnc(C3CCCO3)s2)c1 +CC(C)OC(=O)CCNC(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +CC(C)c1noc(CCNC(=O)c2cc(C(C)C)[nH]n2)n1 +CC(NC(=O)Nc1ccccc1)C(=O)NCc1ccc2c(c1)OCO2 +CC(OCCC1CCCN(C(=O)OC(C)(C)C)C1)c1ccccn1 +CCc1onc(C)c1NC(=O)Nc1ccccc1OCC1CC1 +Cc1nn(C)c(C)c1S(=O)(=O)NCc1ccsc1 +c1cc(COC2CCC3C2OCCN3Cc2ccoc2)ccn1 +O=C(Nc1ccc(OC(F)F)c(Cl)c1)C1CC2CCC1O2 +N#Cc1ccc(NC(=O)NCCS(=O)(=O)c2ccccc2)cc1 +CN(CC(O)C1CC1)C(=O)COc1ccccc1C(C)(C)C +COc1c(Cl)cc(Cl)cc1-c1cc(C)nc(N)n1 +CCN(Cc1cnn(C)c1)C(=O)CCNS(C)(=O)=O +COCCOc1ccc(Cl)cc1C(=O)N1CCN(CCO)CC1 +CCCC1CN(S(C)(=O)=O)CC1NC(=O)c1cc(C)n[nH]1 +CC(C)CCC(=O)N1CCN(C(=O)c2ccc3c(c2)OCCO3)CC1 +CCc1onc(C)c1NC(=O)NC(C)C1CCC1 +CN(CC1COc2ccccc2O1)C(=O)Nc1nncs1 +COCc1cc(CN(C)Cc2cc(=O)c3cccc(Cl)c3[nH]2)n[nH]1 +COCCNC(=O)C12CCC(c3nc4ccccc4nc31)C2(C)C +CC(C)(O)CCC=Cc1ccc(S(C)(=O)=O)cc1 +Cn1c(SCC(=O)NCC(=O)c2ccccc2)nnc1C1CC1 +Cc1noc(C)c1CCN1CCn2c1nc(-c1ccccc1)cc2=O +NC(=O)NC(C(=O)Nc1ccccc1)c1ccccc1 +CC(O)CC(C)CNC(=O)Nc1cccc(Oc2ccncc2)c1 +COc1ccc2nc(N(CC3CCCO3)C(=O)C3CC3)sc2c1 +CC(C)C(C)NC(=O)CSc1nc2ccccc2n1C +Cc1c(-c2cn(CCN(C)S(C)(=O)=O)nn2)oc2ccccc12 +Cc1nc2cc(C(=O)NCc3ccccc3)ccc2n(C)c1=O +CNc1nnc(SCC(=O)NC(C)c2cccs2)s1 +COc1ccc(OC)c(C(O)CSc2nnc(C3CC3)n2C)c1 +OC1CCCN(c2nc(-c3ccncc3)nc3ccccc23)C1 +CCn1cc(CCNS(=O)(=O)c2c(C)noc2C)c2cccnc21 +O=C(NCCc1cccc2cccnc12)c1c[nH]nc1-c1ccccc1 +CCn1cc(C(=O)Nc2ccccc2C)c(=O)c2cc(F)ccc21 +Cc1ccnn1CCc1nc(CC(C)C)nn1-c1ccccc1 +COc1cccc(NC(=O)Cn2cnc(C(C)C)cc2=O)c1 +O=C(COC(=O)c1cnccn1)Nc1ccc(C(F)(F)F)cc1 +Cc1nc(-c2csc(S(=O)(=O)NCc3ccco3)c2)no1 +O=C(c1cc2cc(F)ccc2[nH]1)N1CCCCCC1 +Cc1ccc(NC(=O)CC2CC3CCC2C3)c(O)c1 +NS(=O)(=O)c1cc(C(=O)NCc2cccc(F)c2)ccc1Cl +COc1cc(C)ccc1Oc1ncnc2c1cnn2C +Cc1c(C(=O)Nc2cccnc2)cnn1-c1ccccn1 +C=CCc1cc(CNC(=O)c2occc2C)cc(OC)c1OC +CCC(C)(C)NC(=O)c1cccc(-n2cnnn2)c1 +CC(=O)Nc1ccc(Sc2ncnc3c2oc2ccccc23)cc1 +Cc1ccncc1NC(=O)N1CCCC2(CC=CCC2)C1 +O=C(NCC(O)COc1ccc(F)cc1)NC1CC1 +O=C(C1CCCCC1)N1CC(S(=O)(=O)c2ccc(F)cc2)C1 +CCCn1c(C)nnc1SCC(=O)N(C)Cc1ccccc1F +CNC(=O)CC(C)N(C)c1nc2c(s1)c(C)nn2C +Nc1ccccc1OCC(=O)NCc1ccccn1 +O=S(=O)(CC1CCOCC1)N1CCC(Oc2cccnc2)C1 +CC1CCN(C(=O)NCc2ccc(C(=O)N(C)C)cc2)CC1 +Cc1nc(CNC(=O)Nc2ccc(-n3cncn3)c(F)c2)cs1 +Cc1ccsc1CNC(=O)C1CCN(c2ccc(C#N)cn2)CC1 +CCOC1CCN(C(=O)Nc2nncs2)CC1 +COc1ccc(NC(=O)c2cccn3nccc23)cc1OC +CCc1cc(N2CCN(CCOC)CC2)n2ncnc2n1 +Cc1nc(C)c(N)c(-c2ccc(OC(C)(C)C)cc2)n1 +Cc1ccc(-c2noc(CCCC(=O)Nc3cccc(C)n3)n2)cc1 +CC1CCC(NC(=O)N2CCCC(NS(C)(=O)=O)C2)CC1 +COCCN(Cc1ccoc1)S(=O)(=O)c1ccc(C)cc1 +CC(C)S(=O)(=O)NCc1ccnc(Oc2ccccc2)c1 +COC(=O)N1CCCC(C(=O)NCC(C)c2cccs2)C1 +COc1ccc(NC(=O)c2cccc3ncccc23)cn1 +O=C(CCC1CCCO1)NCc1cc(F)cc(Br)c1 +O=C(Nc1ccc(-n2cc(Cl)cn2)nc1)c1cccs1 +CN(C(=O)c1cccc(-n2ccnn2)c1)C(CO)C(C)(C)C +Cc1sc(=O)n(CC(=O)NCCOc2cccc(Cl)c2)c1C +CCOC(=O)c1cnn(CCOc2ccccc2)c1N +COc1ccc(C(O)CNC(=O)NCc2cnc(C)s2)cc1 +CCOC(=O)CSc1nnc(-c2nc3ccccc3nc2C)n1N +CCN(CC1CCOC1)C(=O)NCc1cc[nH]n1 +CN(C(=O)Cc1cccc(N)c1)c1cccc(F)c1 +CC(C)c1noc(-c2cc(-c3ccccc3)on2)n1 +Cn1cnnc1C1CCCN1C(=O)OC(C)(C)C +CCOC(=O)C1CCC2(CC1)CN(C)C(=O)c1ccccc1O2 +CC(C)Cc1nc(C#N)c(N2CCC(C(N)=O)CC2)o1 +CC(O)CC1COCCN1C(=O)NC1CC=CC1 +CC(C)(C)c1cc(C(=O)Nc2ccc(Oc3cccnc3)nc2)[nH]n1 +COCCOc1ccc(CNC(=O)N2C(C)CCCC2C)cc1 +Cc1cc(NC(=O)COC(=O)c2ccc(-n3cccn3)cc2)n(C)n1 +CN(Cc1nc2ccccc2s1)C(=O)CNC(=O)C(C)(C)C +COc1ccc2oc3c(c2c1)NC(=O)CN=C3c1ccccc1 +Cc1cc(CN(C)C(=O)Cn2cccc(C(F)(F)F)c2=O)no1 +COc1cc(C(=O)NCC2CN3CCCCC3CO2)cc(OC)c1C +CN(CC(=O)N1CCCC1)C(=O)NCCc1cccs1 +N#CC1CN(C(=O)COCC2CCCO2)CCN1Cc1ccccc1 +Cc1csc2nc(O)c(C(=O)NCC(C)O)c(=O)n12 +Cc1cc(NC(=O)C2CC2)sc1C(=O)N1CCCC(C(N)=O)C1 +CCOc1ccc(F)c(C(=O)N2CCC3OCCCC3C2)c1F +CN(C)C(=O)CN1CCN(Cc2ccc(F)cc2)C1=O +Cc1cc(C)n(-c2ccc(C(=O)OCC(=O)C(C)(C)C)cc2)n1 +CCN(C(=O)c1cc(F)ccc1F)C1CCN(c2ccccc2)C1=O +CC(C)Sc1ccc(C(=O)N(C)C2(C#N)CCC2)cc1 +CC(C)NC(=O)C1CCN(c2cc(N3CCCCC3)ncn2)CC1 +Cc1nc(C)n(Cc2cccc(NC(=O)Nc3cnccc3C)c2)n1 +Nc1ccccc1S(=O)(=O)NCCOc1ccccc1 +COC(=O)N1CCN(C(=O)c2ccc(=O)[nH]c2)CC1 +COc1ccc(OCC(C)NC(=O)Cn2c(C)cc(C)nc2=O)cc1 +CCS(=O)(=O)NC(c1cccc(F)c1)c1nccn1C +COc1ccc(Cl)cc1NS(=O)(=O)c1cc(C)sc1C +Cc1ccc(C(NC(=O)c2cc(C)nc(N)n2)c2ccncc2)cc1 +Cc1ccc(C(=O)NC(C)(C)c2noc(C(C)(C)C)n2)cn1 +CCOc1cc(C)c(C(O)CCCCO)cc1Cl +CCOC(=O)CC1CCCCN1C(=O)Cn1nc(C)ccc1=O +Cc1ccc(-c2noc(Cn3cc(C)c(=O)[nH]c3=O)n2)nn1 +O=C(CCc1ccc(Cl)cc1Cl)OCCN1CCOC1=O +CSc1cccc(NC(=O)CSc2nc(C)cc(C)c2C#N)c1 +CCc1nc2ccccc2n1CC(=O)N(C)Cc1ccc(O)cc1 +CN(CC(C)(C)O)c1ncc(Br)cn1 +COC(=O)CC(C)C(=O)Nc1cc(F)ccc1OC +COCCNC(=O)NCC(C(C)C)N1CCOCC1 +Cn1cc(-c2nc(CSc3ncccn3)cs2)cn1 +CN(C)C(=O)c1cccc(-c2cc(O)cc(F)c2)c1 +CC(=O)N1CCN(S(=O)(=O)Cc2cccc3cccnc23)CC1 +CCNC(=O)c1cccc(NC(=O)Cn2ccc(=O)n(C)c2=O)c1 +COc1ccc(NC(C)c2ccc(C#N)cc2)cn1 +O=S(=O)(NCCc1cccc(F)c1)N1CCOCC1 +CCn1ccnc1Cn1ccc(-c2cccc(-c3nccs3)c2)n1 +COc1cc(Cl)c(C)cc1NC(=O)N(C)C(C)CC#N +CN(C)c1ccc(C(=O)NCCC2CCCO2)cc1 +Cn1c(C(=O)NCC(=O)NCc2cccc(F)c2)cc2occc21 +COc1ccccc1Nc1cc(-n2ncc(C(C)=O)c2C)nc(C)n1 +O=C(NCCc1cccnc1)Nc1cnn(-c2ccccc2)c1 +CC(=O)Nc1cc(-c2ccccc2)nn1-c1ccccc1 +Cc1ccc(OS(=O)(=O)c2ccc(C#N)cc2)cc1C +COCc1cccc(NC(=O)CCC(=O)OC)c1 +CCCOCC(=O)NC(C)c1ccc(C)c(F)c1 +CN(C)C(=O)c1cc(Cl)c(Br)c(Cl)c1 +COc1cccc(NC(=O)NCC#Cc2ccccc2OC)c1 +C#CCCN1CCN(C(=O)Cc2cc(C)[nH]n2)CC1 +NC(=O)COC(=O)c1nn(-c2ccccc2F)c2c1CCC2 +CN(C)C(=O)Cc1ccccc1NCc1cc(-c2ccccc2)no1 +O=C1c2ccccc2NC(c2ccco2)N1Cc1cccnc1 +CC(=O)N(C)Cc1cccc(NC(=O)CCN(C)c2ccccc2)c1 +Cn1cc(Br)cc1C(=O)Nc1ccc2cn[nH]c2c1 +Cn1cc(C2CC3(CCN(C(=O)c4ccsc4)CC3)NC2=O)cn1 +Cn1c(SCC(=O)NCCc2c(F)cccc2F)n[nH]c1=O +CCNC(=O)N1CCN(C(=O)c2ccc(SCC)nc2)CC1 +CC(=O)NCC(=O)NCC(=O)N(C)Cc1cnn(C)c1 +Cc1nn(C)c(C)c1CCN(C)S(=O)(=O)c1ccc(C(C)C)cc1 +CC(Nc1ccc(N2CCCC2=O)cc1)C(=O)Nc1ccccc1C#N +COc1cccc(NC(=O)c2nccc3c(N)ccc(C)c23)c1 +COCC(C)NC(=O)c1c2c(nc3ccccc13)CCC2 +CC(C)C(NC(=O)c1ccco1)C(=O)NC(C1CC1)C1CC1 +Cc1cc(C(=O)N2CCCC2c2nccs2)c2ccc(F)cc2n1 +Cc1cc(OCc2ccc(F)c(F)c2)nc(-n2nc(C)cc2C)n1 +Cn1cc(C(=O)NCc2ccc(OCc3ccccc3)cc2)nn1 +COCCNc1nc(-c2cc(C(C)C)oc2C2CC2)cs1 +CCCC(C)Nc1ccc(S(=O)(=O)N(C)C)cc1N +Cc1nnc2n1CCN(C(C(N)=O)c1ccccc1)C2 +O=C1C(NS(=O)(=O)c2c[nH]cn2)CCCN1Cc1ccccc1 +Cc1ccc(NC(=O)c2c[nH]c(=O)n(-c3ccccc3)c2=O)c(C)c1 +CC(=O)Nc1ccccc1NC(=O)COc1ccc(Cl)c(C)c1 +O=C(NCc1cccnc1)c1cc(C(=O)C2CC2)c[nH]1 +CC(C)N(Cc1cccc(Cl)c1)C(=O)Nc1ccncc1 +CC(NC(=O)c1ccccc1)C(=O)N(C)CCOc1ccccc1 +O=C(CSc1nc2cc(Cl)ccc2[nH]1)NCc1ccco1 +COCC(=O)NC(CC(=O)OC)c1ccccc1Cl +Cc1nc2ccc(C(=O)N3CCOCC3)cc2s1 +Cc1nc(N2CCc3onc(C(=O)N(C)C)c3C2)c2sccc2n1 +O=C(NC1(c2ccc(F)cc2)CCC1)c1ccc[nH]c1=O +CCCc1nnsc1C(=O)NCCc1ccsc1 +C#CCN1C(=O)C(Cc2cccc(C)c2C)Oc2cc(N)ccc21 +c1ccc(CCSc2nnc(-c3cccs3)o2)nc1 +Cc1ccccc1S(=O)(=O)Cc1nc(N)nc(N(C)C)n1 +CN(CC1CCCC1)C(=O)NCc1cccc(Cn2cncn2)c1 +CSc1n[nH]c2ncnc(N3CC(C)OC(C)C3)c12 +COCCc1noc(C(C)(C)c2ccc3c(c2)OCCO3)n1 +COc1ccc(CCNC(=O)NCc2nc(C)cs2)cc1OC +CC(=O)N(CCc1ccccc1)CC(=O)Nc1nccs1 +CCNC(=O)Cn1nc2c3c(cccc31)C(=O)c1ccccc1-2 +Cc1ccc(CN(C)C(=O)c2c[nH]c3ccccc23)o1 +CCCNC(=O)c1cc2c([nH]c1=O)CC(c1ccco1)CC2=O +Cn1nc(CNc2ccc(F)cc2F)cc1C(F)(F)F +O=C(Cc1c(F)cccc1F)Oc1ccc(F)cc1 +O=c1onc(-c2ccccc2)n1Cc1nc2ccccc2o1 +COc1sc(CN2CCNC(=O)C2C(C)C)cc1Br +Cc1ccccc1-n1nnc(CO)c1Cc1cccs1 +Nc1cc2c(=O)[nH]cnc2cc1-n1cc(Cl)cn1 +COC(=O)CSc1nc(-c2ccncc2)n[nH]1 +CSc1ccccc1C(=O)NCC(C)N1CCOCC1 +O=C(OC1CCN(C(=O)c2ccccc2F)CC1)c1cscn1 +CC1(C(=O)N2CCN(c3nc4ccccc4s3)CC2)CCCO1 +Cc1nc(C)n(CC2CCCN2Cc2nc3ccccc3n2C)n1 +COc1ccc(S(=O)(=O)NCc2ncoc2C)c(C)c1C +COc1cccc2ncn(CC3CCCCC3O)c(=O)c12 +CN(Cc1cnc2ccsc2c1)Cc1nc(-c2cccnc2)no1 +COc1ccccc1NC(=O)CCNC(=O)c1cc2scnc2[nH]1 +Cc1n[nH]cc1CN1CCN(C(=O)c2c(F)cccc2F)CC1 +O=C(Nc1cc(F)ccc1F)c1cnn2c3c(cnc12)CCCCC3 +CN(Cc1ccc2c(c1)OCO2)C(=O)Cc1ccc2c(c1)CCC2 +NC(COC(F)(F)F)c1cccc(Br)c1 +COc1cccc(CN2CCN(C(=O)c3cc[nH]n3)CC2CCO)c1 +Cc1ccc2c(c1)NCCN2CC(=O)NCC1CCCO1 +CCNC(=O)N1CCc2nc(NC(=O)c3cccs3)sc2C1 +NS(=O)(=O)C1CCCN(C(=O)c2ccccc2Cl)C1 +CCNC(=O)N(CCCN1CCOCC1)Cc1ccco1 +Cc1cnc(NC(=O)COc2ccccc2Br)s1 +Oc1cc2c(cc1Cl)CCNC2c1nccs1 +CCn1nc(C)c(S(=O)(=O)NCCCO)c1C +CC1CCCN(C(=O)Cn2cc(Br)ccc2=O)C1 +COc1cccc(CCNC(=O)Cc2cn(C)c3ccccc23)c1 +CCOc1ccc(C(=O)NC(C)(CC)C(=O)OC)cc1 +CCOc1c(Cl)cc(C(=O)Nc2c(C)nn(C)c2C)cc1OC +Cc1nccn1-c1ccc(F)cc1CNCc1cc(C(N)=O)cs1 +Cn1cc(C(=O)Nc2cnn(-c3ccccc3S(C)(=O)=O)c2)cn1 +CCC1CN(C(=O)c2cnc(C)nc2C(C)C)CC1N1CCOCC1 +CNC(=O)COC(=O)C(NC(=O)c1ccc(F)cc1)C(C)C +CC(C)Oc1nccc(C(=O)N(C)C)c1OC1CC1 +O=C(CNC(=O)c1ccc2noc(-c3ccccc3)c2c1)NCCO +O=C(Nc1ccc(O)c(-c2nc3cnccc3o2)c1)c1ccc(F)cc1 +CN(C)S(=O)(=O)N1CCC2(O)CCN(c3nccs3)CC2C1 +COc1ccc(Cl)cc1C(=O)Nc1nn(C)c2c1C(C)CC(=O)N2 +O=C(NCCCc1nc2ccccc2[nH]1)c1cccc(-n2cccc2)c1 +Cc1ccc(C(=O)N2CCN(C)C3(CCNC(=O)CC3)C2)c(=O)n1C +CC(C)Sc1nnc2c3ccccc3n(C)c2n1 +COc1cccc2c(=O)n(CC(=O)N3CCc4ccccc43)ccc12 +N#Cc1cc(F)c(NCc2cccc(C(=O)N3CCCC3)c2)c(F)c1 +Cc1ccc(C2NCCc3c(F)cc(O)cc32)s1 +COc1ccc(C#CCNC(=O)Nc2ccccc2)cc1 +COCC(=O)Nc1ccc2c(c1)-c1ccccc1C2 +CCOC(=O)c1nnc2nc(C)nn2c1C=CN(C)C +Cc1ccc(NS(=O)(=O)c2ccc(N)cc2)cc1F +CCc1noc(CN(Cc2nc(CC)no2)C2CCCCC2C)n1 +Cc1nc2ccc(NC(=O)c3sc(C)cc3OC(F)F)cc2o1 +CC(=O)Nc1ccc(-n2ccnc2-c2ccccn2)cn1 +O=C(NCc1ccccc1Cl)c1ccc(Cn2cccn2)o1 +CCCc1nc(NC(=O)CC2C(=O)N=C(C)N=C2C)sc1CC +COC(=O)c1cc(-c2cc(C)ccc2OC(C)C)nn1C +O=C1CN(C(=O)c2cc(-c3ccccc3)on2)c2ccccc2N1 +CCNC(=O)C(C)NC(=O)c1ccc(OCC(C)C)cc1 +O=C(OCC(=O)N1CCCCCC1)c1ccnc2ccccc12 +CC(=O)NCCC(=O)Nc1nnc(CC(C)C)s1 +Cc1c(C(=O)NCc2ccccc2)cccc1N(C)S(C)(=O)=O +COc1ccc(C(=O)N(CC(F)(F)F)c2nc(C)cs2)cc1 +COC(=O)Nc1cccc(NCC(=O)NCc2ccc(C)cc2)c1 +Cc1cccc(NC(=O)c2cccn(Cc3cccc(F)c3)c2=O)n1 +COc1cc(OC)c(-c2cc(C#N)c(C(C)C)o2)cc1OC +Cc1noc(C)c1CSc1ncccc1C(=O)NC1CC1 +CCCn1c(S(=O)(=O)Cc2ccccc2)n[nH]c1=O +COc1ccc(NC(=O)NC2CCN(CC(F)(F)F)C2)cn1 +COc1cc(CNC(=O)c2ccc(OCC3CC3)cc2)ccn1 +Cc1nc(C2CCCN(C(=O)Cc3cccnc3)C2)no1 +CNC(=O)NCC(=O)Nc1ccccc1OC(C)C +COC(=O)c1csc(NCc2cccc(O)c2)n1 +COc1ccc(C(O)C(C)NC(=O)CC2CCOCC2)cc1 +COC(=O)CCC(=O)Nc1ccccc1NS(C)(=O)=O +COc1ccc(CNC(=O)c2sccc2SC)cc1F +Cc1cc2cc(NC(=O)C3CCOCC3)ccc2[nH]1 +Cn1ccnc1C(=O)C1CCCN(C(=O)CCc2ccco2)C1 +CCc1ccc(NC(=O)c2n[nH]c3ccccc23)cc1S(N)(=O)=O +COCCN(Cc1cncs1)Cc1ccc(F)cc1Cl +O=C(NCC(O)c1c(F)cccc1F)c1cnn(-c2ccccc2)n1 +CCNC(=O)c1cccn(Cc2ccc(Cl)cc2Cl)c1=O +COc1ccc2oc(C(=O)NCCC(=O)N3CCCC3)c(C)c2c1 +CC(C)N(CCc1nccs1)C(=O)Cc1c[nH]c2ccccc12 +O=C(NCC#Cc1ccccc1F)C1CC=CCC1 +Cc1n[nH]c(C)c1S(=O)(=O)Nc1cccc2cccnc12 +CC(NC(=O)NCc1cnn(Cc2ccccc2)c1)c1ccncc1 +O=C(Cn1nc2c(cc1=O)CCCC2)NCCC1=CCCCC1 +CC(C)(C)c1ccc(C2(C(=O)NCc3ccncc3)CC2)cc1 +CCS(=O)(=O)N1CCCC(C(=O)Nc2cccc(C)c2C)C1 +Cc1cc(C)c(S(=O)(=O)NCCC(N)=O)c(C)c1 +CC(=O)N1CCc2cc(S(=O)(=O)N3CCCC(C)C3)ccc21 +CCc1nc2c(s1)C(OC(=O)c1cnn(C)c1C(F)F)CCC2 +OCC1NCCc2c(Cl)ccc(Br)c21 +CNC(C)(C(=O)OC)c1cc(F)c(Cl)cc1Cl +CCCCCn1ccc2c(cnc3nc(-c4cccnc4)nn32)c1=O +COc1ccc(-c2nnc(NC(=O)C(C)(C)C)o2)cc1 +CCCS(=O)(=O)N(C)C1(C#N)CCN(C)CC1 +COCC(O)CN(C)S(=O)(=O)c1ccccc1N +O=C(CS(=O)(=O)c1ccc(F)c(F)c1)Nc1ccc(Cl)cc1 +COc1ccc(C(=O)N2CCOC(C)C2)cc1S(=O)(=O)N(C)C +COc1cccc(OCC(=O)Nc2ccc(C)cc2N)c1 +CN(C(=O)c1cncc(C(=O)N(C)c2ccccc2)c1)c1ccccc1 +CC(C)NC(=O)c1cc2c([nH]c1=O)CC(c1ccco1)CC2=O +COc1cccc(C(=O)N(C)CCc2ccc(F)cc2)c1 +CCOc1ccc(C(=O)Nc2ccc(S(=O)(=O)N(C)C)cc2)cc1 +COCc1cccc(CNC(=O)Cc2ccc(C)s2)c1 +CC1CN(CC2CN(C(=O)NC(C)(C)C)CC2CO)CC(C)O1 +CCOc1nc(N(CCO)C2CCCC2)ccc1N +Cc1ccoc1C(O)c1cc2[nH]c(=O)[nH]c2cc1Br +COc1cccc(C(=O)Nc2ccccc2N(C)C)c1F +CC(C)n1nccc1-c1nnc(NC(=O)c2ccccc2)o1 +Cc1cc(Cl)ccc1NC(=O)NCc1ccc(C(=O)N(C)C)cc1 +CC(=O)N1CCc2ccc(Br)cc2C1 +CC(=O)c1cccc(S(=O)(=O)NC(C)c2cccs2)c1 +O=S(=O)(NCc1cc2ccccn2n1)c1ccc(F)cc1F +CCCCNC(=O)c1cnc(N2CCCC2)nc1C +Cc1nc2ncnn2c2ccn(-c3ccc(F)c(Cl)c3)c(=O)c12 +O=C1Cc2cc(NC(=O)C3COc4ccc(F)cc4C3)ccc2N1 +O=C(NCCc1cc(Cl)c2c(c1)OCCO2)c1cccs1 +COc1ccccc1-c1nn(-c2ccccc2)cc1C(=O)NC1CC1 +CCOC(=O)c1cc2c(=O)n(C)c(=O)n(C)c2nc1N +CN1C(=O)C2CCC1CN(C(=O)c1cnc(N3CCOCC3)nc1)C2 +CCC(=O)c1ccc(SCC(=O)Nc2nccs2)cc1 +O=C(NC1CCCc2c1cnn2Cc1ccccc1)c1cscn1 +COc1ccc(OC)c(NC(=O)C(O)c2ccc(C)cc2)c1 +O=C1NCCN1c1ccc(NCc2ccc3c(c2)OCCO3)cc1 +Cc1cc(=O)[nH]c(-c2cccc(NC(=O)COCC3CC3)c2)n1 +CC(C)CC(C#N)NC(=O)c1ccc(Cl)cc1 +CC(C)COCCNC(=O)c1cc(=O)[nH]c2ccc(Cl)cc12 +CC(=O)NC(Nc1nccs1)(C(F)(F)F)C(F)(F)F +O=C(Nc1cccc(OC2CCCC2)c1)c1csnn1 +Cn1cc(-c2ccco2)nc1CCNC(=O)c1cccn(C)c1=O +CC(OC(=O)c1cccc(-n2cnnn2)c1)C(N)=O +COC(=O)C(C)(C)NC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +CCOc1ccc2c(c1)CN(C(=O)C1CC(=O)N(C(C)C)C1)CC2 +Cc1nc(C)c(C(=O)NCCC(=O)Nc2cccnc2)s1 +CCCN1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1 +Cc1nonc1NC(=O)c1cc2cc(Br)cc(C)c2o1 +Cn1nnc(NC(=O)CSc2nnnn2C)n1 +Cc1ncc(CO)c(CNc2ccc(C(N)=O)cc2)c1O +O=C(Nc1ccc2c(c1)OCCO2)c1nc(-c2ccncc2)no1 +CCn1c(-c2ccc(C)cc2C)ccc(CO)c1=O +CC(=O)c1ccc(NC(=O)N2CCNC(=O)C2C(C)C)cc1C +COc1ccccc1CCN(C)Cc1cnc2cnccn12 +Cc1nc2ccc(NCC(=O)NC(C)(C#N)C(C)C)cc2s1 +O=C1COc2ccc(-c3csc(N4CCOCC4)n3)cc2N1 +O=C(CC1CSc2nccc(=O)n21)Nc1cccnc1 +Cc1nsc(N2CCCN(Cc3cnnn3C)CC2)n1 +CC(CC#N)N(C)Cc1ccccc1OCC(=O)N(C)C +CC(C)N(C)C(=O)Cc1csc(-c2cccnc2)n1 +O=S(=O)(NC1CCCC(O)C1)c1ccc(C(F)(F)F)cc1 +O=C(Cn1cccn1)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +CC(C)C(C#N)OC(=O)CCC(=O)c1ccc(F)c(F)c1 +Cn1cc(CCCNC(=O)CCC(C)(C)C)cn1 +O=C(NCCc1ccccc1F)NCc1cc(=O)[nH]c2ccccc12 +Cc1ccc(N2CC(C(=O)N3CCC(C)CC3)CC2=O)cc1Cl +COC(=O)CCCn1nncc1-c1ccc(N)cc1 +Cc1ccc2cccc(C(=O)NCC3(C(=O)N(C)C)CCCC3)c2n1 +CCc1ccccc1NCc1ccc(NC(C)=O)cc1 +Cc1nnc(SCC(=O)Nc2nc3ccccc3s2)n(N)c1=O +O=C1CC2(CCN(C(=O)c3ccsc3)C2)Oc2ccccc21 +CN(Cc1nc2ccccc2s1)C(C(N)=O)c1ccc(F)cc1 +CC1CN(Cc2nc3c(cnn3C)c(=O)[nH]2)CCO1 +CC(CC(=O)OCC(=O)N1CCNC(=O)C1)c1ccncc1 +NC(=O)c1csc(C(=O)NC2CC2c2cccc(Cl)c2)c1 +Cc1csc(CS(=O)(=O)c2ccccc2)n1 +CSc1nc(C)c(CCC(=O)N(C)Cc2ccncc2)c(C)n1 +Cc1ccc2[nH]cc(CCC(=O)NCc3csc(=O)[nH]3)c2c1 +CC1CCC(N(C(=O)CN2CCOCC2C2CC2)C2CC2)CC1 +COc1cc(NC(=O)c2nc3nccc(C)n3n2)cc(OC)c1 +CCCOc1ccc(-c2cc(NC3CC3)nc(C)n2)cc1 +Cc1nnc(CSc2nnc(C(C)(C)C)n2N)o1 +O=C(CCOc1ccc[nH]c1=O)N1CCc2ccccc2C1 +Cc1cc(NC(=O)c2cc(-c3cccs3)cs2)no1 +O=C(Cc1cnn(-c2ccccc2)c1)Nc1ccc(N2CCCC2)nc1 +Cn1ccc(NC(=O)CCc2cccc(Br)c2)n1 +CCOCCCn1cnc2c([nH]c3ccc(OC)cc32)c1=O +Cc1ccc(C(C)(C)C)cc1C(=O)CN1CCC(=O)CC1 +COc1ccc(C(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)cc1Cl +COCCCNC(=O)NCCc1csc(C)n1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)c1ccco1 +CCOC(=O)c1ccccc1NC(=O)CSc1nc(C)cc(=O)[nH]1 +COC(=O)C1CN(c2cc(OC)ccc2OC)CCC1=O +COc1cn(CC(=O)NC(C)C)c(CSc2ncccn2)cc1=O +Cc1cc(C(=O)N2CCCN(C)c3nc4ccccc4nc32)no1 +CCN(Cc1ccccc1)C(=O)CCc1ccc(O)c(N)c1 +CC(=O)Nc1cccc(C(=O)Nc2nc(-c3ccc(C)o3)cs2)c1 +CNC(=O)c1ccc(CN(C)c2ncnc3c2cnn3CCC#N)cc1 +c1cc(CN2CCC(CN3CCOCC3)C2)c2c(c1)OCCCO2 +Cc1ccc(-c2nnc(SCc3c(C)noc3C)n2C)cc1 +CC(CN1CCOCC1)NC(=O)c1cc2ccccc2[nH]c1=O +O=C(NC1CCC2CCCC21)c1n[nH]c2c1CCCC2 +CC1c2ccsc2CCN1C(=O)c1cn(C)c2ccccc12 +CCN(C)c1ccc(C(=O)Nc2cccc3cn[nH]c23)cc1 +C#CCN1C(=O)CNc2cc(Cl)c(Cl)cc21 +COc1cc(C(=O)N(C)Cc2ccc(F)cc2F)cc(OC)c1C +CC(C)(C)NC(=O)COC(=O)c1ccc(NC(N)=O)cc1 +COc1ccc(Br)c(C(=O)N2Cc3cncnc3C2)c1 +Nc1nccnc1C(=O)N1CCC(CCc2ccccc2)CC1 +CC(C)(C)NC(=O)Cc1n[nH]c(=O)c2ccccc12 +Cc1nnnn1-c1cccc(NCC2CCOC2)c1 +O=C(OCC(=O)N1CCCCCC1)C1CC=CCC1 +O=C(NCCCCN1CCOCC1)c1ccc2ncsc2c1 +CC(c1ccccc1)N(CC1CCC1)S(C)(=O)=O +COc1ccc(C(=O)NCCCC2CCCC2)cc1OC +CC(C)c1cccc(NC(=O)NCCNC(=O)c2ccc(O)cc2)c1 +Cc1ccc(SCC(=O)N2CCCC(O)C2)cc1 +CCn1cc(NCc2ccc(F)c(C)c2)ccc1=O +Nn1c(SCc2ccccc2F)nnc1-c1ccccn1 +Cc1noc(C2CCN(C(=O)c3cccc(-c4ccoc4)c3)CC2)n1 +COCCCNc1nc(C)nc2sc(C)c(C)c12 +O=C(CCCOc1ccccc1)N1CCc2cc(F)ccc2C1 +Cc1ccsc1C(=O)N1CCCn2cnc(COC(C)C)c2C1 +CCC(CC)NC(=O)N1Cc2c(OC)ccc(OC)c2C(O)C1 +CN(CCc1ccc(F)cc1)Cc1nc(-c2cccnc2)no1 +COc1c(C)cnc(COc2ccc(F)nc2)c1C +COCc1cc(C(=O)NCCc2cccc(C)c2)ccc1F +CC(=O)N1CCc2cc(NCc3ccc(Br)cc3)ccc21 +Cc1ccccc1NC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +Cc1csc(=O)n1CC(=O)Nc1ccc2nc(N(C)C)ccc2c1 +N#Cc1cccc(NC(=O)c2nccn2-c2ccncc2)c1 +CC(C)(C)NC(=O)CSc1nc2c3ccccc3ncn2n1 +CCc1onc(C)c1NC(=O)N1CCOC(c2ccc(C)o2)C1 +CC(=O)N1CCC(Cc2ccnc(Cc3ccccc3)c2)CC1 +CN(Cc1nc(-c2ccco2)no1)Cc1[nH]nc2c1CCC2 +CC(CNC(=O)Cn1ccc(=O)n(C)c1=O)N1CCOCC1 +Cc1nc(C)c(C(=O)Nc2ccc(Cl)c(Br)c2)o1 +Cc1ccc(C(=O)NC2CCN(C(=O)OC(C)(C)C)CC2)cc1C +CC(NC(=O)c1ccccc1)C(=O)NC1CCCC1 +COc1ccc2nnc(C(=O)NCc3ccccc3)nc2c1 +Cn1c(CCNC(=O)C2CC2)nc2cc(NC(=O)C(C)(C)C)ccc21 +CC1CCCN(C(=O)C2CC(=O)N(C3CC3)C2)C1 +Cc1cccn2c(CN3CCOCC3)c(C(=O)N3CCCCC3)nc12 +COC(=O)C(C)(NCC1CCCO1)C1CCCCC1 +C#CCNC(=O)c1ccc(OC)c(S(=O)(=O)N(C)C)c1 +CCN(CC(F)(F)F)C(=O)Cc1ccc(C)cc1 +Cc1nn(C)c(C)c1C(=O)Nc1ccc(Oc2ncccn2)cc1 +COC(=O)c1ccc(COc2cccc(-n3cnnn3)c2)o1 +COC(=O)NCC(=O)NC(c1ccccc1)c1cccc(Cl)c1 +Cc1ccc(C(=O)N(C)C)cc1OCc1cc(F)cc2cccnc12 +CN(CCc1ccncc1)C(=O)c1ccn(-c2cccc(F)c2)n1 +Cc1nnc(C2CCN(C(=O)c3sc(C)nc3C)CC2)s1 +CC1CCN(c2nnc(SCCC(N)=O)n2Cc2ccco2)CC1 +Cc1cc(NC(=O)CCN2CCc3ccc(Cl)cc3C2)no1 +COc1cccc(C2NCCc3ccc4c(c32)OCO4)c1 +CN(Cc1ccc(O)cc1)C(=O)CN1C(=O)CSc2ccccc21 +NC(=O)c1cc(N2CCCCC2)ccc1NCC(=O)N1CCOCC1 +NC(=O)c1ccc(C#CCNC(=O)CSc2ccc(F)cc2)cc1 +Cc1ccccc1C(C#N)CC(=O)N1CCC(C)CC1 +C=C(C)Cn1nc(C#N)cc1-c1ccc2[nH]c(=O)oc2c1 +CN(C(=O)COc1cccc(-c2nnco2)c1)C1CC1 +O=C(Cc1csc(N2CCCC2=O)n1)NCc1cscn1 +CCC(=O)Nc1ccc(NC(=O)c2cccc(Cl)c2)nc1 +CSc1ccc(NS(=O)(=O)c2cc(C#N)ccc2C)cc1 +CCOC(=O)c1sc2ncnc(NC(C)C)c2c1C +COc1ccc(CC(C)C(=O)Nc2nn(C(C)C)cc2C#N)cc1 +CC(OC(=O)c1ccc(-n2ccnn2)cc1)C(=O)Nc1ccccc1 +CC(=O)Nc1ccc(NC(C(N)=O)c2ccccc2)cc1Cl +CC(C)NC(=O)N1CCCC(c2nnc(Cc3ccccc3)s2)C1 +C#CCNC(=O)c1ccccc1NC(=O)c1ccc(C)cc1 +Cc1n[nH]c(C2CN(CC(O)c3cccc(F)c3)CCO2)n1 +COC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)C2CC2C)c1C +Cn1nc(C(=O)NCc2ccccn2)c2c1-c1ccccc1SC2 +CCN(CCO)C(=O)c1ccc(CNC(C)=O)cc1 +Cn1cc(S(=O)(=O)N2CCc3c2cccc3C(F)(F)F)cn1 +Cc1cc(OCC#N)nc(Nc2cccc(F)c2)n1 +CC(=O)N1c2ccccc2CC1C(=O)NCc1ccccc1F +Cc1ccccc1C1CC1C(=O)NCc1ncccc1C +N#Cc1nc(C2CC2)oc1N1CCN(C(=O)c2cccs2)CC1 +CN(Cc1cccc2ncccc12)C(=O)c1ccc(F)c(F)c1F +CC(CCc1ccco1)NC(=O)CNC(=O)c1ccc(F)cc1 +CC(=O)Nc1cc(S(=O)(=O)N(C)Cc2ccccc2C)ccc1C +COc1ccc(C(=O)c2cc(N)ccc2OC(F)F)cc1OC +Cc1ccc(OCC(=O)Nc2cccc(O)c2)c(-n2cnnc2)c1 +CCc1noc(CC)c1CC(=O)Nc1ccnc(N(C)C)n1 +COCCOC1CCN(c2ccccc2N)CC1 +CCc1onc(C)c1NC(=O)NC1CCN(CC(F)(F)F)C1 +NC(c1nnc(C2CC2)o1)c1c(F)cc(F)cc1F +COc1ccc(NC(=O)C2CCOC2)cc1OC1CCCC1 +COC(=O)c1cccc(CC(=O)Nc2cc(C)n[nH]2)c1 +COc1ccc2c(ccn2CCC(=O)Nc2cccc(C(C)=O)c2)c1 +CC(Cn1cccn1)OC(=O)c1ccc(N2CCCC2)nc1 +CSc1ccc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)o1 +CN1CC(Cc2cccc(F)c2)Oc2ccc(O)cc21 +COc1ccc(C2CC(C)N(C(=O)C(C)OC)C2)cc1 +Cn1c(=O)oc2cc(NC(=O)NCc3cccc(F)c3)ccc21 +COc1ccc(OC)c(NCc2nc3ccccc3s2)c1 +Cc1cccc(OCC(=O)NCC2CN(CC(C)C)CCO2)c1 +CC(C)NC(=O)Nc1ccc(C(=O)Nc2cnc3ccccc3c2)cc1 +Cc1ccc(CNC(=O)N2CCC(C(N)=O)CC2)c(N(C)C)c1 +CCc1ccccc1CNC(=O)NCCNC(=O)c1ccccc1 +CCN(Cc1cccc(F)c1)C(=O)c1ccc(NC(=O)C2CC2)cc1 +Cc1noc(C2CCCN(C(=O)COc3ccccc3)C2)n1 +O=C(Cc1nc2sc3c(c2c(=O)[nH]1)CCCC3)NC1CCCC1 +CCC(O)Cn1nc(C)nc1Cn1c(C)cc(=O)c2ccccc21 +CCCCN(CC(F)(F)F)C(=O)c1cc(C)no1 +Cn1cnnc1SC(C(=O)NCc1ccccc1)c1ccccc1 +Cc1ccc(C#N)cc1NC(=O)C1(c2ccccc2)CC1 +CCn1nc(C)cc1C(=O)NCC(O)c1cc(Cl)cc(Cl)c1 +COc1cc(OC)cc(C(=O)NCCNC(=O)c2ccccc2)c1 +CC(=O)c1cncc(-c2ccc3c(c2)CCN3C(C)=O)c1 +CCC1NCCc2c(Br)cc(F)cc21 +O=C(N1CCN(c2ccccc2F)CC1)C1(c2ccccc2)CC1 +COc1ccccc1OCCC(=O)N(C(C)C)C1CCC1 +CCCOc1ccccc1-c1ccc(CO)c(=O)n1CC +COc1cccc(C(=O)Nc2ccc3nc(-c4ccncc4)[nH]c3c2)c1 +Cc1nc(CN(C)S(=O)(=O)c2cc(F)cc(F)c2)cs1 +Cn1ncc(Cl)c1-c1nn2c(Cc3ccccc3)nnc2s1 +COC(=O)C1=C(C)N=C(C(=O)C(C)Sc2ccccn2)C1C +COc1ccccc1NC(=O)Cn1nnc2ccccc21 +CC(C)c1nc(C2CCCN2C(=O)c2ccsc2)no1 +O=C(Cn1c(CO)nc2ccccc21)Nc1cc(F)ccc1F +Cc1nc(C2CCCN(c3ncc(C#N)cc3Cl)C2)no1 +CCOC(=O)C(N)Cc1nc2c(OC)cccc2s1 +NC(=O)c1cccc(OS(=O)(=O)c2cccc(Cl)c2)c1 +CCCN(CC1CC1)C(=O)CSc1ncnc2sccc12 +CC(C)N1CCN(C(=O)c2cn3cc(-c4ccccc4)ccc3n2)CC1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(C(C)=O)cc1 +CC(NC(=O)CCC(=O)c1ccc2c(c1)CCCC2)c1ccccn1 +C=CCn1c(=O)c2c(ncn2CC=C)n(-c2ccc(F)cc2F)c1=O +Cc1c(Cl)cccc1NC(=O)NCCNC(=O)c1cccnc1 +CCS(=O)(=O)c1ccc(CC(=O)Nc2sccc2C#N)cc1 +Cc1ccc(F)cc1C(=O)Nc1ccccc1C(=O)N(C)C +CCn1nc(C)c(CNC(=O)NCCOC2CCCCC2C)c1C +CC1CCCN(C(=O)c2ccc(NC(=O)CC#N)cc2)C1 +Cc1csc(CCNC(=O)N(Cc2ccccc2F)C2CCC2)n1 +CCc1sc(C(=O)N2CCCC(n3nc(C)nc3C)C2)cc1C +CC(C)NC(=O)c1ccc(NC(=O)c2ccco2)cc1 +Cc1cc(C)nc(C(C#N)C(=O)c2sc3ccc(F)cc3c2C)n1 +Cc1cc(C(=O)Oc2ccc3c(c2)OCO3)c(C)s1 +Cc1cc(C(=O)Cn2cnc3sccc3c2=O)c(C)n1C1CC1 +CC(C)=CCN1CCN(C(=O)c2ccccc2F)CC1 +CC(C)C(CNS(=O)(=O)c1ccc(C#N)cc1)N1CCOCC1 +Cc1cccc(C)c1OCc1nc(C)c(CO)s1 +Cc1ccc(C(=O)Nc2cccnc2-n2cccn2)o1 +O=C(NCCn1nc(-c2cccs2)cc1C1CC1)c1ccsc1 +CC(C)c1nnc(NC(=O)CN2CCN(c3ccccc3)CC2)s1 +CSc1ncc(C(=O)Nc2ccc(C)cc2)c(=O)n1C +O=S(=O)(Cc1ccccc1)NCCCc1ccccc1 +COC(=O)c1cc(S(=O)(=O)NCC2CCCO2)cn1C +CCCc1cc(NC(=O)c2c[nH]nc2-c2ccccc2Cl)n[nH]1 +CCN(CCC(=O)OC)C(=O)c1ccccc1OC +Cc1ccc(C(C)NC(=O)c2ccoc2C)cc1C +CCCn1nc(C(=O)NC(C#N)c2c(F)cccc2Cl)ccc1=O +Cc1nc(C2CCN(Cc3cnc(C(C)C)nc3)C2)cc(=O)[nH]1 +COc1ccc2c(c1O)CCNC2c1ccc(C#N)cc1 +CCc1ncc(C(=O)N(C)Cc2ccccc2C(F)(F)F)cn1 +CCOC(=O)CN(C)C(=O)c1ccc(OC)c(Br)c1 +CCOc1ccccc1Oc1cc2c(cc1N)OCCO2 +Cc1ccccc1-n1ncc2c1ncn1nc(-c3ccco3)nc21 +Cc1nc(C)c(CC(=O)NCCSc2ccccc2)c(=O)[nH]1 +Cc1nc(C)c(C(=O)OCC(=O)NC2CC2)s1 +O=C(Nc1ccc2c(c1)CCC2)C1CC2CCCC(C1)C2=O +CCNC(=O)C1CC(=O)N(c2ccccc2)C(C)=C1C(=O)OC +OCCSc1nnc(Nc2ccc(F)c(Cl)c2)s1 +Cc1ncc(CNC(=O)Nc2cnn(C)c2)s1 +Cc1cccc(NC(=O)NCc2nnnn2-c2ccc(F)c(F)c2)c1 +CCOc1ccccc1C(=O)Nc1cc(N2CCOCC2)ncn1 +Cc1cccn2cc(CC(=O)NC(C)c3nnc4ccccn34)nc12 +CC(Sc1nnc(-c2ccncc2)o1)C(=O)NCc1cccs1 +c1ccc(CN2CCOC3C(COCc4cccnc4)CCC32)nc1 +CCOC(=O)C=C1CCN(C(=O)OCc2ccccc2)CC1 +Nc1c(-c2ccccc2)nnn1-c1ccc(Br)cc1 +O=C(Nc1ccccc1)C1CC2CN(S(=O)(=O)C3CC3)CC1O2 +CCSc1ccc(Cl)cc1C(=O)NC1CC(=O)N(C)C1 +CC1(C)CN(Cc2cc(F)cc(C(F)(F)F)c2)CCO1 +CN(CCC(F)(F)F)C(=O)c1cc(N2CCCC2=O)ccc1Cl +COC(=O)c1cc(CNC2(C(=O)OC)CCCCC2)c(C)s1 +Nc1onc(C(F)(F)F)c1-c1ccc2c(c1)OCO2 +CCOc1cccc2c1OCC(O)C2N1CCOCC1 +O=c1c2ccccc2nc2n1CCN2CCOc1ccc(F)cc1 +Cc1ccc(C(=O)c2ccccc2C(=O)NCc2ccnn2C)cc1C +O=C(CCC1CCCCC1)NC1CCCc2occc21 +COc1ccc(-c2noc(C(=O)NC(C)C)c2N)cc1 +CCS(=O)(=O)N1CCCc2cc(C(=O)NC)ccc21 +Cc1cnc(NCc2cccc(OC(F)F)c2)nc1-c1ccnn1C +COCc1cc(CNC(=O)Nc2cnn(C(C)C)c2)ccc1F +Cc1ccc(N2CC3(CCN(C(=O)C(C)C)C3)CC2=O)cc1 +CC(=O)NCc1cc(=O)[nH]c(CC2=CCCCC2)n1 +CS(=O)(=O)c1ccc(-c2cc(NC3CC3)ncn2)cc1 +COC(=O)Nc1cccc(NC(=O)C2CCOCC2)c1 +Cn1c(N)c(C(=O)COC(=O)c2ccccc2)c(=O)n(C)c1=O +CC(OC(=O)c1cc(S(C)(=O)=O)ccc1Cl)c1ccccc1 +Cc1cnc(NC(=O)COc2ccc(Cl)cc2C)s1 +Cn1cc(-c2nnc(SCC(=O)Nc3ccccc3)n2C)cn1 +CC(C)N(C)C(=O)c1ccc(CNc2ncc(C#N)cc2Cl)cc1 +CCN(Cc1ccccc1Cl)C(=O)CCCn1cncn1 +Cc1ccc(NC(=O)NC2CC(=O)N(c3ccc(F)cc3)C2)c(C)c1 +O=C(c1ccccc1Cl)N1CCC(C(O)c2ccccc2)CC1 +Cc1nc(C)c(C#N)c(SC(C(=O)N2CCCC(C)C2)C(C)C)n1 +CC(Sc1nnc2ccc(N)cn12)C(=O)Nc1ccc(Cl)cc1 +CCC1CCCC(NC(=O)c2ccc3c(c2)[nH]c(=O)c(=O)n3CC)C1 +NC(=O)c1cccc(CC2CCN(C(=O)C3CCOCC3)C2)c1 +COc1ccc(CC(=O)OCC(=O)N2CCCC2)cc1 +Cc1ccc(F)cc1NC(=O)NCC(F)(F)F +CC(=O)NC(C(=O)Nc1nc2ccccc2s1)C1CCCC1 +CN(CCOc1cccc(Cl)c1)C(=O)c1ccc(F)cc1 +COc1cccc(C(=O)N(C)c2cccnc2N(C)C)c1F +COC(=O)NCC(=O)NCc1cccc(NC(C)C)c1 +CCCCS(=O)(=O)NCC(=O)Nc1cc(F)c(F)c(F)c1 +Cc1nn(C)c(C)c1C(=O)Nc1ccc2c(c1)NC(=O)CO2 +CCOc1cc(C(=O)CCC(=O)NC2CCCCCC2)ccc1O +COc1ccc(Cl)cc1CNc1cccc(C(N)=O)c1C +Cc1nc2ccccc2c(=O)n1Cc1cccnc1 +CCOC(=O)c1nc(NCC(C)O)c2ccccc2n1 +COc1cccc(F)c1C(=O)N(Cc1cccnc1)C(C)(C)CO +O=C(c1scnc1C1CC1)N1CCOC2(CCOCC2)C1 +Cc1ccncc1NC(=O)NC(c1ccccc1)C(C)C +CS(=O)(=O)NCC(=O)NC1CCCC(C(F)(F)F)C1 +C#CCN1CCN(C(=O)NCCOc2cc(C)cc(C)c2)CC1 +CCOCc1cccc(NC(=O)C2CC3CCC2O3)c1 +Nc1cc(C2CC2)nn1-c1ccc(Cl)c(Cl)c1 +CC(C)(C)C(NC(=O)c1ccc(S(N)(=O)=O)o1)c1cccs1 +CS(=O)(=O)c1ccc(F)c(NCc2cc(=O)n3ccccc3n2)c1 +CC(C)(C)CC(=O)N1Cc2ccccc2CC1C(N)=O +Cc1noc(C)c1CN1CCCc2cc(Cl)ccc21 +CN(C1CC1)S(=O)(=O)c1ccc(NC(=O)N2CCOCC2)cc1 +CCNc1nnc(-c2c3c(nn(CC)c2=O)CCCC3)s1 +Cc1ccc(O)c(C(=O)NCC2CN(Cc3ccccc3)CCO2)c1 +Cc1cccn2cc(CSc3ccc(O)cc3)nc12 +CCNC(=O)CCc1nc(-c2cccc(C)c2)no1 +CC(=O)N(C)C1CCN(C(=O)C2COc3ccc(F)cc3C2)CC1 +Cc1nccc(C(=O)Nc2ccc3nc(C4CC4)sc3c2)n1 +CC(C)(C)Cc1noc2ncc(C(=O)Nc3ccc(O)cc3)cc12 +CC(NS(C)(=O)=O)C(=O)NCCSc1ccccc1 +CCc1nc2n(n1)CCCC2NC(=O)c1cc2cc(F)ccc2o1 +C#CCNC(=O)c1cc2ccccc2cc1OCc1c(C)noc1C +CCN(CC(=O)NC(C)C(C)C)Cc1nc2ccccc2c(=O)[nH]1 +C=CCOc1cc(C(=O)NC(C)c2ccncc2)cc2occc12 +Nc1nc(N2CCCCC2)ncc1C(=O)Nc1cccnc1 +Cc1cc(C)n(-c2ccc(NC(=O)c3ccc4cc[nH]c4c3)cn2)n1 +Cc1cc(C)c(CNC(=O)NCc2ccoc2)c(C)c1 +OCc1cc(Br)cc(CO)c1OCC1CCC1 +CCC(=O)N1CCCN(C(=O)Nc2cc(C)ccc2OC)CC1 +CCCN(CCC)C(=O)c1cccc(NC(=O)c2ccco2)c1 +Cc1cccc(OCCNC(=O)COc2nnc3ccccn23)c1 +CNC(=O)c1c(NC(=O)Cc2ccccc2)sc2c1CCC2 +O=C(c1ccncc1)N1CCN(c2cccc3[nH]c(=O)oc23)CC1 +CCOC(=O)c1sc(NC(=O)CN2CC(C)OC(C)C2)nc1C +O=C(NCc1ccc(F)cc1Cl)c1n[nH]c(=O)c2ccccc12 +O=C(Nc1ccc2c(c1)OCCO2)c1cc(C2CC2)nc2ccccc12 +CC(OCc1ccccc1)C(=O)NC(C)c1ccncc1 +CC(O)CNC(=O)c1ccccc1OCC1CCCO1 +CCOC(=O)CN1CCCN(C(=O)Cc2ccc(F)c(F)c2)CC1 +Cc1csc(C2CN(Cc3cccn3C)CCO2)n1 +O=C(NC(Cc1c[nH]cn1)C(=O)N1CCCC1)C1CCCC1 +COCc1nc2cc(C(F)(F)F)ccc2n1Cc1ccco1 +CCC(CC)C(=O)Oc1ccc(-n2cnnn2)cc1 +COc1cc(C(=O)N2CCCC(OCc3cccnc3)C2)ccn1 +COc1ccccc1NC(=O)CCSc1nc(C)cc(C)c1C#N +CN1C(=O)CN=C(c2ccccc2Cl)c2cc(Cl)ccc21 +NC(=O)Cn1cc(NC(=O)c2ccc(Br)cc2O)cn1 +COc1ccc(CCN(C)c2ncnc3c2cnn3C)cc1OC +CC(C)COc1ccc(CC(=O)N2CCC(=O)CC2)cc1 +NC(=O)c1ccc(C(=O)Nc2ccc(OC(F)F)c(F)c2)cc1 +COC(C)C(=O)Nc1nc2ccc(N)cc2s1 +CC(C)CC1COCCN1C1CCN(CC(F)(F)F)C1=O +CCN(CC)C(=O)CCC(=O)N(C)CC(=O)N(C)C +Cc1n[nH]c(C)c1C(=O)N(CCO)CC(F)(F)F +CCCNC(=O)c1cccc(NC(=O)OCC)c1 +CNc1ccc(C(=O)NCC2CCCCO2)cc1C +CCn1ccc(-c2nnc(SCc3ccccn3)n2CC)n1 +Cc1nc2cnccn2c1NCCC(=O)NCCC1=CCCCC1 +COc1cccc2c1OCC(CNC(=O)CN1CCCCCC1=O)C2 +CC(C)c1ncncc1C(=O)N1CCN(Cc2cscn2)CC1 +CCOC(=O)C1=C(C)C(C(=O)NC(C)C)=NC1C +CC(C)Oc1ccccc1C(=O)NCc1nncn1-c1ccccc1 +CC1CC(c2cccc(C(F)(F)F)c2)Cn2nc(N)nc21 +CN(Cc1ccco1)C(=O)c1cccc2cccnc12 +CCOCCn1c(C2CC2)nc2ccc(Cl)cc21 +N#Cc1cccnc1NCCNC(=O)c1cc(Br)c[nH]1 +CCOC(=O)N1CCN(C(C)C(=O)Nc2cc(C)no2)CC1 +Cn1cc(C(=O)Nc2ccc3c(c2)C(=O)NCC3)nn1 +Cc1ccccc1Cn1ccc(NS(=O)(=O)c2cn(C)nc2C)n1 +Cc1nc2ncnc(N3CCN(CCO)CC3)c2[nH]1 +CS(=O)(=O)Nc1ccccc1CNC(=O)C1CCOC1 +C=CCn1c2cc(C)sc2c2cnn(Cc3cccnc3)c(=O)c21 +N#Cc1ccc(-c2ccc(F)c(F)c2)nc1N1CCCC1 +Cc1ccc(F)cc1NC(=O)C12CC3CC(CC(O)(C3)C1)C2 +COc1ccccc1NC(=O)CNc1ccc(C)cc1 +Cc1ccnc(NC(=O)c2cccc(Cn3nc(C)cc3C)c2)n1 +COc1cccc(C(=O)N2CCC3(CCOC3)C2)c1F +CCc1onc(C)c1NC(=O)N1CCC(OC2CCCCC2)CC1 +Nc1ccc(Br)c(C(F)(F)F)c1O +Cn1cc(CCNC(=O)Nc2cccc(N3CCCCC3)c2)cn1 +COc1cc(OC)nc(N2CCN(Cc3cccc(C#N)c3)CC2)n1 +O=C1CN(S(=O)(=O)c2ccc3c(c2)CCCC3)CCN1 +Cc1nn2c(=O)c3c([nH]c2c1-c1ccccc1F)CCCC3 +Cc1ccc(NC(=O)Cc2noc3c(N)cc(C)cc23)cc1 +CCCn1cc(Cl)cc1C(=O)N(CC)CC(=O)OC +O=C(N=c1[nH]c2ccccc2n1-c1ccccc1)C1COCCO1 +Cc1nc(C)c(C(=O)N2CCC(O)(c3cccnc3F)CC2)s1 +Cc1ccc(C(C)NC(=O)c2cc(C)oc2C)cc1 +COC(=O)c1[nH]c(C)cc1NS(=O)(=O)c1ccccc1Cl +CC(C)C(C)(C#N)NC(=O)c1ccc(-n2ccnn2)cc1 +COc1ccc(Cl)cc1NCCC(=O)Nc1ccnn1C(C)C +O=C1COc2ccc(O)cc2N1CCc1ccccc1 +Cc1sc(=O)n(CC(=O)NC2CCCCCC2)c1C +O=C(Cc1n[nH]c2c(Cl)cccc12)NCc1ccccn1 +Cc1cc(Br)ccc1-c1ccc(CNn2cnnc2)o1 +CCOc1cc(C)ccc1NC(=O)CNC(=O)Cc1cccc(F)c1 +CC(C)n1cc(C(=O)NC2CCOC(C)(C)C2)c2ccccc2c1=O +COc1cccc(C(=O)N(C)C)c1OCC1CCC1 +NS(=O)(=O)CCNC(=O)c1c[nH]nc1-c1ccc(F)cc1 +C=CCOc1ccc(C(=O)N(C)C2(C(=O)OC)CCCCC2)cc1 +Cn1nnnc1COc1ccc(C(=O)Nc2ccncc2)cc1 +OCc1csc(Cc2ccc(Br)cc2)n1 +Cn1c(=O)n(CCC(=O)N2CCC3(CC2)OCCO3)c2ccccc21 +CC1CC(C)CN(C(=O)COC(=O)c2cc(=O)[nH]c3ccccc23)C1 +Cc1cc(C)n2nc(C(=O)Nc3ccccc3C)nc2n1 +CCN(CCC#N)C(=O)CSc1nnc(-c2ccco2)n1C +C=C(C)COC(=O)Cc1n[nH]c(=O)c2ccccc12 +CNC(=O)c1cc(Cl)c(=O)n(Cc2cccc(C(F)(F)F)c2)c1 +COc1c(O)c(Cl)cc2c1C(c1ccccn1)NCC2 +Cn1nc2c(cc1=O)CN(Cc1ccc(Cl)c3cccnc13)CC2 +O=C(Nc1cc(S(=O)(=O)N2CCCC2)ccc1O)c1ccco1 +NS(=O)(=O)Cc1ccc(NC(=O)c2cn[nH]n2)cc1 +Cc1cc(C(=O)N2CCC(c3nnc(C4CC4)s3)CC2)no1 +CCn1c(C)cc(C(=O)CSc2nc3nc(C)cc(C)n3n2)c1C +CCOC(=O)C(C)(C)N(C)Cc1ccc(C(=O)NC)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)COCC(F)(F)F +Cc1ccccc1C(=O)N1CCc2cc(N)ccc21 +COC(=O)c1ccc2c(c1)C1CC(C)(O2)N(c2ccccc2)C(=O)N1 +Cn1c2ccc(N)cc2n2c(C3(c4ccccc4)CC3)nnc12 +COc1ccccc1NC(=O)C(C)Nc1cnn(C(C)(C)C)c1 +CCCn1nc(C)c(CN2CCOCC2CC(C)C)c1C +Cc1cccc(NC(=O)Cn2c(=O)c3ccccc3n3nncc23)c1 +CNC(=O)c1nnn(-c2ccc(Br)cc2)c1N +CCC(C)NC(=O)c1nc2c3c4c(sc3ncn2n1)CCC(C)C4 +CCCn1c(C)cc(C(=O)COc2ncnc3sccc23)c1C +Cc1cc(C)cc(C(=O)NCC(=O)Nc2ccc3c(c2)COC3)c1 +CCN(C(=O)CN1CCCc2cccc(F)c21)C1CC1 +COC(=O)c1ccccc1Cn1ccnc1-c1cnccn1 +Cc1cnc(C(=O)NCc2ccnc(OC3CCC3)c2)cn1 +CCOc1cc2c(cc1OC)C(c1ncccn1)NCC2 +CCc1nc(CCNC(=O)NCc2ccc(C)cc2N(C)C)cs1 +Cn1c(=O)[nH]c2cc(C(=O)OCCNC(=O)c3ccncc3)ccc21 +Cc1ccc(F)cc1C(=O)Nc1cc(C(=O)N(C)C)ccc1Cl +CC(=O)c1ccc(NC(=O)CN(C)C(=O)c2ccccc2)cc1C +COc1ccc(-c2csc(NC(=O)c3ccco3)n2)cc1OC +COc1ccc(Cc2nn(CCO)c(=O)[nH]c2=O)c(OC)c1 +CNC(=O)c1cccc(NCC(c2cccs2)N2CCOCC2)n1 +CCOC(=O)c1ccc(S(=O)(=O)NCc2ccco2)cc1 +O=C(CO)N1CCCC(c2cncc(Nc3ccccn3)n2)C1 +CNC(=O)c1ccc(C)c(NC(=O)c2csc(-c3ccoc3)n2)c1 +CC1c2cccn2CCN1C(=O)CCc1ccc(F)cc1 +COc1ccc(C(=O)Nc2c(C)cccc2C)c(F)c1 +CCC(C)C(NC(=O)c1ccn(C)c(=O)c1)C(N)=O +CN(Cc1cc(Br)cs1)C(=O)c1ccon1 +N#Cc1cccc(NC(=O)Nc2ccc3c(c2)OCCO3)c1 +Cc1noc(C)c1C(C)NC(=O)c1cc(Cl)cc(Cl)c1 +O=C(Cn1cnnn1)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +CC(NC(=O)CNC(=O)C12CC3CC(CC(C3)C1)C2)c1cccnc1 +CC(C)(C)C(C#N)NC(=O)c1cccc(N2CCCNC2=O)c1 +Cc1nn(C)c2ncc(C(=O)N3CCC(C)C4CCCCC43)cc12 +CN(CCc1ccncc1)c1cnn(C)c(=O)c1Br +COc1nc2ccccc2nc1N1CCC(CO)CC1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cccc(-n2cnnc2)c1 +O=C(NCc1cccs1)c1cnn(-c2ccccc2)n1 +COc1ccc(C2CCCN2C(=O)C2CCC2)cc1 +CC(=O)Nc1ccc(SC(C)C(=O)NC(C2CC2)C2CC2)cc1 +COc1ccc(Cc2nc3ccc(Cl)cn3c2N)cc1OC +CC(C)NC(=O)CN1CCN(c2ccccc2)CC1 +Cc1cccc(COCc2n[nH]c3c2CN(C(=O)CC2CC2)C3)n1 +CC1=Nn2c(nnc2-c2ccc(Br)cc2)SC1 +Cc1cccc(N(C)C(=O)C2CCCN(S(C)(=O)=O)C2)c1C +c1ccc(-c2nnc(Sc3ccc4nccnc4n3)o2)cc1 +CCOC(=O)c1nnc(CNC(=O)OC(C)(C)C)o1 +CCOCCCNC(=O)C1(C)CCC(=O)N1c1ccccc1F +O=C(NCc1ncc(-c2ccccc2)o1)c1cc2ccccc2oc1=O +CCCNC(=O)c1coc(NC(=O)c2ccccc2)n1 +Cn1ccnc1Cn1c(CC#N)nc2ccc(F)cc21 +Cc1nc(Cc2ccccc2)sc1C(=O)N1CCCS1(=O)=O +Cc1csc(C2CCCN(S(=O)(=O)c3cn(C)cn3)C2)n1 +Clc1ccc(CSc2nnc3ncccn23)cc1 +O=C(NCC1OCCc2cn(CC3CCOCC3)nc21)C1CC1 +Cc1ccc(C(O)(CC(=O)OCc2ccccn2)C(F)(F)F)o1 +CC(NC(=O)N(C)Cc1ccccc1-c1ccccc1)c1nncn1C +CCC(C)Oc1ccc(NC(=O)c2cccnc2)cc1 +COc1ccccc1NC(=O)Nc1cccc(N)c1 +O=C(CCCNC(=O)NC1CCCCC1)Nc1cc(F)cc(F)c1 +COc1cccc(OCCNC(=O)Cn2c(=O)[nH]c3ccccc32)c1 +Cc1cccc(C)c1OCCCn1cnc(C2CCC2)cc1=O +CCC(Nc1cc(NC(C)=O)ccc1OC)C(=O)Nc1cc(C)on1 +O=C(COC(=O)c1cc2c(s1)CCC2)Nc1ncccn1 +C=CCNC(=O)C1CCCN1C(=O)Nc1cccc(Cl)c1 +COc1cc(C)nc(N2CCC(CS(N)(=O)=O)CC2)n1 +O=C(NC1CC1c1cccc(Cl)c1)c1cccc(-n2cccn2)n1 +N#Cc1ccc(N2CCCC(C(=O)NCC3CC3)C2)c(F)c1 +Cc1ccsc1CNC(=O)CSc1nnc(C2CC2)n1C1CC1 +CNc1nnc(SCC(=O)c2ccc3c(c2)CCCC(=O)N3)s1 +N#Cc1sc2sc(C#N)c(-c3ccco3)c2c1N +O=c1c2ccccc2oc2nc(-c3ccncc3)ccc12 +CCc1nnsc1C(=O)N(C)Cc1cc(C)c(OC)c(C)c1 +O=C(Cc1nc(-c2ccc(O)cc2)cs1)Nc1ccc(F)cc1 +CCSc1ccccc1C(=O)N1CCN(Cc2ccccc2)CC1 +O=C(NCCCO)C1CC(=O)N(c2cccc(Br)c2)C1 +CC(CC#N)N(C)C(=O)c1[nH]ncc1Br +Cc1cnn(-c2ccccc2)c1NC(=O)c1ccc2c(c1)OCCO2 +C=CCN(Cc1ccccc1)CC(O)c1ccccc1 +O=C(Cn1ccccc1=O)Nc1ccc(NC(=O)c2ccco2)cc1 +Cc1nnc(SC(C)C(=O)NCc2ccccc2F)s1 +CC(=O)c1nnn(CC(=O)N2CCCCC2)c1C +O=C(Cc1c(F)cccc1F)NCc1ccc(OCC2CC2)nc1 +CC(=O)NC(C)C1NCCc2c1cc(F)c(Cl)c2F +CC(=O)Nc1ccc(F)c(NCc2ccccc2)c1 +Cc1cc(C(=O)NC(c2ccc(Cl)cc2)C2CC2)on1 +O=C(c1cc(C2CC2)n[nH]1)N1CCN(c2ncccn2)CC(O)C1 +CCC(CC)C(=O)c1c[nH]c(C(=O)NCc2ccco2)c1 +CN(C)S(=O)(=O)c1cccc(NC(=O)c2cc(F)cc(F)c2)c1 +CC(C)(C)CC(=O)Nc1cccc(Cl)c1-n1cncn1 +CC(C)C(=O)N1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1 +CCC1(CC)Oc2ccc(O)cc2N(CCCO)C1=O +CCCOCc1ccccc1CNC(=O)c1cc(F)cc2[nH]cnc12 +Cc1cccc(NC(=O)NCc2ccccc2)c1C(=O)N1CCCC1 +Cc1cc2nc3c(=O)n(C)c(=O)n(C)c3nc2cc1C +Cc1ccc2sc(NCc3cccnc3)nc2c1C +CCCNC(=O)c1cccc(C(=O)NCc2cc(C(C)C)no2)c1 +O=C(CSc1nnnn1-c1cccc(F)c1)Nc1ccc(F)cc1 +CC(O)(CNC(=O)NCCN1CCOCC1)c1ccsc1 +CNC(=O)C1(C)CN(C(=O)c2cccc3[nH]c(C)c(C)c23)CCO1 +Cc1cc(C)c(CNC(=O)c2ccc(=O)n(C)n2)c(C)c1 +CC(C)(C#N)NC(=O)CSc1ccc(F)c(F)c1 +CC(C#N)CN(C)C(=O)Nc1ccccc1Cl +CCOc1ccc(COC(=O)C2CCCN2)cc1Cl +COc1cccn(C(C)C(=O)N2CCCC2)c1=O +COc1ccc(-c2ccc(C(=O)NCc3cc(=O)[nH]cn3)o2)cc1 +O=S1(=O)N=C(NCCc2ccc(Cl)cc2)c2ccccc21 +CCc1ccccc1CNC(=O)NCc1cc(C(C)C)no1 +O=c1[nH]cnc2c1cnn2-c1ccc2c(c1)OCCO2 +O=C(CCN1CCOC(C2CCCO2)C1)Nc1cccc(F)c1 +CCn1c(CN2CCN(CCOC)CC2)nc2cc(F)ccc21 +CCOc1ccc(F)c(C(=O)NCCNC(C)=O)c1F +O=C(c1ccccn1)N1CCN(C(c2ccccc2)C(F)(F)F)CC1 +CCC(C)NC(=O)CCCc1nc2ccccc2s1 +CC(C)CC(C(=O)N1CCc2sccc2C1)N1CCCCC1=O +O=S(=O)(CCN1CCOCC1C1CC1)c1ccccc1 +CCn1nc(C(=O)Nc2ccc(C)cc2)c(=O)c2ccccc21 +Cc1cc(CNC(=O)Nc2ccc(C(F)(F)F)cc2)no1 +O=C(NCc1ccc2c(c1)OCO2)C1CCCN(c2cnccn2)C1 +CC(CNC(=O)N(C)C(C)c1ccncc1)Oc1ccc(F)cc1 +CC(CN(C)C(=O)NC(C)C1CCOC1)c1nccs1 +COC(=O)c1ccncc1NCc1cccc(O)c1 +Cc1cccc2c(=O)n(CC(=O)NCCO)cnc12 +Cc1cc(C(=O)NCC2CCCO2)nn1C(F)F +C#Cc1ccc(CNC(C)c2cnc(-c3ccncc3)nc2C)cc1 +CCOC(=O)C(C)NS(=O)(=O)c1c(Cl)cccc1Cl +Cc1nc(CN2C(=O)CCC3C2CCN3C(=O)N2CCCC2)cs1 +CC1CCCCN1S(=O)(=O)NCCc1ccccc1Cl +CC(C)(C)OC(=O)N1CCCCC1C(=O)NCc1nnc2n1CCC2 +CC(=O)Nc1cccc(C(=O)OCC(=O)c2ccc[nH]2)c1 +COc1ccc(Nc2nnc(-c3cc(C)on3)o2)cc1 +O=C1CCN(C(=O)c2[nH]nc3c2CCCC3)CCN1CC1CC1 +CN(C)c1nc(CNc2ccccc2OCC2CC2)ns1 +CC(C)(CNC(=O)Nc1ccccc1F)N1CCOCC1 +Cc1ccc(C(=O)CCC(=O)Nc2nnc(CC(C)C)s2)s1 +O=C(CN1CCOCC1)Nc1ccc(C(=O)NCc2ccco2)cc1 +COC(=O)C1=C(C)N(C)C(=O)NC1c1ccc(SC)cc1 +O=C(OCc1nc(-c2ccsc2)no1)c1ccccn1 +Cc1c(NC(=O)C(C)C)cccc1S(N)(=O)=O +CC1CCCN(C(=O)c2ccc(-n3cnnc3)cc2Cl)C1 +CN(Cc1ccc(Cl)cc1)C(=O)COc1ccc(C(N)=O)cc1 +COC(=O)C(NC(=O)C(C)c1ccsc1)c1ccccc1 +Brc1cnn(-c2cncc(C3CC3)c2)c1 +CCSc1ccc(C(=O)N2CC(=O)Nc3ccccc32)cc1 +Cc1noc(C)c1C(C)NC(=O)C1COc2ccccc21 +N#CC1(NC(=O)Cc2ccc(OCC(F)(F)F)cc2)CCC1 +CCCCN(C)c1ncnc(N(CC)CC)c1N +COCCOCC1CCN(C(=O)C2(C#N)CCCC2)C1 +CCCc1nc(NCc2c(C)nn(C)c2C)c2c(n1)c(C)nn2CC +COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)c1ccc(C)o1 +Cc1ccccc1-n1c(C)nnc1SCC(=O)NC1CCCC1 +CN(C)S(=O)(=O)N1CCCC1CC(=O)c1cccs1 +CCCn1cnc2cc(NCc3ccccn3)ccc21 +CCCn1cc(NC(=O)c2c[nH]nc2-c2ccccc2F)cn1 +O=C(COc1ncnc2sccc12)N1CCc2ccccc21 +Cc1ccc(-c2n[nH]cc2CN2CCCC3(C2)OCCO3)o1 +Cc1nn(C)cc1CCC(=O)N1CC2(CCCC2)c2ccccc21 +CCN(C)C(=O)CC(NC(N)=O)c1cccc(Oc2ccccc2)c1 +CC(c1cccc(Cl)c1)N(C)C(=O)c1ccc(-n2ccnn2)cc1 +COc1ccc2[nH]cc(C(=O)Nc3cc(C)cc(C)c3)c(=O)c2c1 +Cc1ccccc1N1CCN(C(=O)c2cnn3cccnc23)CC1=O +C=CCSc1ncc(Cl)c(C(=O)Nc2ccc(C(N)=O)cc2)n1 +COCC(=O)N1CCC(c2cccc(Cc3ccc(F)cc3)n2)CC1 +CCc1c(C(=O)NC(COC)C(N)=O)cnn1-c1ccc(C)cc1 +COC(=O)c1cnn2c(C(F)(F)F)cc(C3CC3)nc12 +Cc1cc(-n2c(C)cc(C(=O)CN3CCC(C(N)=O)CC3)c2C)no1 +COc1ccc(NC(=O)CCn2c(=O)oc3ccccc32)cc1Cl +Cc1nc(CNC(=O)CCCn2ccc3cc(Cl)ccc32)oc1C +Cc1ccc(C2=CCN(C(=O)c3ccc(C)[nH]c3=O)CC2)cc1 +CN(CC(=O)NC1CC1)C(=O)c1ccccc1OCc1cscn1 +CC(=O)N1CCN(C(=O)CNc2ccccc2C(=O)NC2CC2)CC1 +CN(C)c1ncccc1NC(=O)CCc1cnn(C)c1 +COC(=O)C(c1cccc(C#N)c1)N1CCC(Cc2cnn(C)c2)C1 +NC(=O)C(Cc1ccccc1)NC(=O)Nc1ccccn1 +COC(=O)C(CC(C)C)NC(=O)Nc1ccccc1 +O=C(COc1ccc(F)cc1Cl)NC1CCCC1 +COC(=O)c1ccc(C#Cc2ccccc2)cc1C(=O)OC +Cc1cccc2c(N3CCCN(S(C)(=O)=O)CC3)c(C#N)cnc12 +Cc1cc(C)n(-c2ccc(C(C)O)cc2Br)n1 +N#Cc1cc(C#N)c(SCCNC(=O)OCC(F)(F)F)nc1N +Cc1oc(-c2ccccc2)nc1C(=O)OCc1cc(=O)c(O)co1 +CCC(C)n1nccc1NC(=O)c1cc2cccc(OC)c2o1 +CC(C)C(=O)N1CCc2cc(C(=O)NC3CC3)ccc21 +CC(C)n1ncc2c(C(=O)N(C)Cc3ccccc3)c3c(nc21)CCC3 +Cc1ccccc1-n1ccc2c(nnc3ncnn32)c1=O +CS(=O)(=O)c1ccc(Nc2ccc(F)cc2)c(S(C)(=O)=O)c1 +CC(CO)(NC(=O)Nc1ccc(-c2nnnn2C2CC2)cc1)C1CC1 +Cc1cccc(NCC(=O)NC(C)(C#N)C2CC2)c1 +O=C(c1cccc(O)c1)c1ccc2c(c1)OCCCO2 +CCNC(=O)c1cccc(NCC(=O)N(CC)CC)c1 +CCc1nn(C)c(CC)c1CNc1ccn(-c2ncccc2Cl)n1 +O=C(NCc1cccs1)c1cc(C(F)(F)F)n[nH]1 +CCSc1nnc2c(n1)OC(c1ccccn1)Nc1ccccc1-2 +COCc1ccc(CNC(=O)NC2Cc3ccccc3C2)cc1 +O=C(CCNc1ncccn1)NCCc1c[nH]c2ccccc12 +CC(=O)c1c[nH]c(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)c1 +CCCC1CCC(NC(=O)C2CC(=O)N(C)C2c2cccnc2)CC1 +CC(C)NC(=O)CSc1ncnc2nc(N3CCCC3)sc12 +CN(CCc1ccccc1)S(=O)(=O)N1CCCCCC1 +COC(=O)C(NC(=O)c1cc(C)nc2c1cnn2C(C)C)C(C)C +CCC(NC(=O)c1cc(=O)c2ccccc2o1)c1ccc(OC)cc1 +COc1cc(-c2c(C#N)c(N)nc3c2CCC3)ccc1O +CCCCCNC(=O)C1CCCN(C(=O)OC(C)(C)C)C1 +O=C(Nc1ccccc1-n1cccc1)c1ccco1 +COC(=O)CNC(=O)c1csc2c1CCC(C)C2 +O=C(c1ccc(OCCSc2ccccc2)cc1)N1CCCC1 +COc1cc(C)ccc1OC(=O)C(NC(=O)c1cccs1)C(C)C +N#Cc1ccccc1OCCN1CCN(Cc2ccncc2)CC1 +COc1ccccc1N1CC(C(=O)NCc2ccccc2C)CC1=O +CC1=NC(=O)C(Cc2nc(CCc3ccccc3)n[nH]2)C(C)=N1 +Cc1ccc(C(=O)Nc2cccc(-n3cnnc3)c2)cc1F +CC(C)(C)C(=O)COc1nncc(-c2ccccc2)n1 +CCn1cnc2c(F)cc(Br)cc2c1=O +CCc1nn(C)c(OC)c1CN1CCOC2(CCC2)C1 +COc1ccccc1CCNC(=O)c1ccc(CNC(N)=O)cc1 +COc1ccccc1CNC(=O)COc1ccccc1C(N)=O +COc1cccc2cc(C(=O)NCCCn3ccc4cccnc43)oc12 +CC1Oc2ccc(O)cc2N(Cc2ccccc2C#N)C1=O +COc1cccc2c(=O)c(C#N)cn(Cc3ccc(C)cc3)c12 +CC(=O)c1cc(C(=O)NCCS(=O)(=O)N2CCCC2)cs1 +COC(=O)C(NC(=O)c1ccc(Oc2ccccc2)nc1)C(C)C +CCN(CCCN1CCOCC1)Cc1cccc(Cl)c1 +CC1(C)COc2c(Br)cccc2NC1=O +Cc1ccc2ncc(C(=O)Nc3ccccc3C(=O)N(C)C)n2c1 +CC(NCC1CCCO1)C(=O)c1ccc2c(c1)CCCN2 +CC(=O)N1CCC(C(=O)NCCCn2cccc2)CC1 +Cc1cccc(-c2c(CO)nnn2Cc2c(C)noc2C)c1 +CCOC(=O)c1cc(S(=O)(=O)N(C)C(C)C)ccc1Cl +CSc1ccsc1C(=O)N(C)c1ccccc1S(C)(=O)=O +CC(Oc1ccccc1)C(=O)OCC(=O)NC1CCCCC1 +CC(=O)Nc1c(-c2cc(F)ccc2F)nc2ccccn12 +CN(C)C(=O)c1ccc(C#CCNC(=O)c2ccc(N(C)C)cc2)cc1 +CC(C)CNC(=O)C1CCCN(c2cnccn2)C1 +CC(NC(=O)c1cnccn1)c1ccc(Cl)c(Cl)c1 +Cc1c(C)n(Cc2ccccc2)c2ncnc(N3CCOCC3)c12 +COc1ccc(CN2C(=O)C(CCC(=O)NC(C)C)N=C2O)cc1 +CCCNC(=O)CNC(=O)CCn1cnc2ccccc21 +CC(NCc1nnc(C(=O)Nc2ccccc2)s1)c1ccncc1 +CC(=O)c1cccc(OC(=O)CSc2ccccc2F)c1 +CCC(NC(=O)c1cc(-c2ccccc2F)[nH]n1)c1ncc(C)[nH]1 +Cc1ccn2c(=NC(=O)CNC(=O)OCc3ccccc3)[nH]nc2c1 +COC(=O)N1CCC(CNC(=O)c2cccc(C)c2)CC1 +Cc1nnc(-c2cn(CC(=O)Nc3ccccc3C)c3ccccc23)o1 +Fc1ccc(NCc2nc(-c3ccsc3)no2)c(F)c1F +O=C(CO)N1CCCC1c1ccc2c(c1)OCCCO2 +Cc1ccc(O)c2c1C(c1ccc[nH]c1=O)NCC2 +CCCOCC(=O)Nc1ccc(Sc2nncs2)c(Cl)c1 +CCc1ccc(CNS(=O)(=O)CCCO)cc1 +Cc1ccc(-n2cnnc2SCC(=O)Nc2ccccc2)c(C)c1 +O=C(NCCC(O)c1ccccc1)c1ccc2c(c1)OCO2 +CCOc1cccc(C(=O)NC(C)c2ccncc2)c1 +CNC(=O)COC(=O)c1cnn(-c2ncccc2Cl)c1C(F)F +CC(C)Cn1ncc(C(=O)OCC2CCCO2)c1C1CC1 +O=C1CC(NC(=O)NCc2cccc3ccccc23)CN1 +COC(=O)C(C)n1ccc(=O)c2cc(OC)c(OC)cc21 +CC(C)CN(CC(C)C)C(=O)CCC1CCCO1 +COC(C(=O)N(C)c1ccccc1F)c1ccccc1 +CC(NC(=O)c1ccc[nH]1)c1ccc(Oc2cccnc2)c(F)c1 +O=C(Nc1cc(Cl)c(Cl)cn1)c1ccncc1F +Cc1ccc(C(=O)Nc2ccc(N3CCCCC3)cn2)c(=O)[nH]1 +Cc1coc2c1C(NC(=O)c1ccccc1Cl)CCC2 +CCn1cc(NC(=O)c2cc3ccc(OC)cc3[nH]2)cn1 +Cc1nn2cccnc2c1C(=O)NCc1cccc(NC(C)C)c1 +Cc1cccn2c(CN(CCCO)C3CCc4ccccc43)cnc12 +CC(C)CNS(=O)(=O)c1ccc(OC(F)(F)F)cc1 +COCCNC(=O)c1cc(C2CC2)nc2onc(-c3ccco3)c12 +O=C(NCC(c1ccccc1)N1CCOCC1)c1cc(F)cc(F)c1 +O=C(CN1CCOCC1)c1ccc2c(c1)OCCCO2 +CCCCNC(=O)Cn1c(=O)ccc2cc(N)ccc21 +CCS(=O)(=O)NC(c1cccs1)C(C)(C)C +O=C(Cc1nnc(-c2ccsc2)o1)NCc1cccs1 +Cn1nccc1C1(O)CC2CCC(C1)N2C(=O)c1ccncc1 +CC(Sc1ncnc2c1cnn2C)C(=O)N(C)Cc1ccccc1 +Cc1nc(C)c(C(C)N(C)Cc2ccccc2N2CCOCC2)s1 +CN1CCOc2ccc(NC(=O)c3ccc4ccccc4c3)cc2C1=O +CN(CCc1ccccc1)C(=O)CNC(=O)NC1CCCCC1 +COCC(=O)N1CCC2CN(CCC(C)C)S(=O)(=O)C2CC1 +Cn1cnc2cc(OC(=O)c3cc(-c4ccccc4)n[nH]3)ccc21 +CCS(=O)(=O)c1ccc(Cl)c(C(=O)N2CCCCCC2)c1 +NC(=O)Cc1csc(NC(=O)c2cc(Cl)ccc2F)n1 +Cc1ccc(=NS(=O)(=O)c2ccc(N3CCCC3=O)cc2)[nH]c1 +O=C(NCc1cccnc1)c1ccc(-c2ccc(F)cc2)s1 +N#Cc1ccc(SCC(=O)NCc2ccco2)cc1C(F)(F)F +O=S(=O)(NCc1nccs1)C1=Cc2ccccc2CC1 +CCOC(=O)Cc1csc(NC(=O)C2CCCCC2)n1 +COCCNC(=O)Nc1nn(-c2ccccc2Cl)cc1C +CC1Cc2ccccc2N(C(=O)c2ccn(C)c2)C1 +O=C(Nc1ccc(F)cc1)c1ccc(=O)n(Cc2cccc(F)c2)c1 +O=C(NCc1ccccc1)C1CCCN(C(=O)Nc2cccs2)C1 +O=C(CNC(=O)OCc1ccccc1)Nc1ccc(Cl)cc1 +c1ccc(COC2CCN(c3ccc4nncn4n3)CC2)cc1 +COc1ccc(C(=O)N2CC(C)OCC2C)cc1N +C=CCN(Cc1cccnc1)c1ncnc2sc3c(c12)CCNC3 +Cc1ccnc(SCC(=O)Nc2nc(-c3ccccc3)cs2)n1 +CC(=O)NCCNS(=O)(=O)c1c(C)cc(C(C)(C)C)cc1C +COc1ccc(F)cc1NC(=O)Cn1c(=O)oc2ccccc21 +COCCCNC(=O)CSc1ccc(N)nc1 +N#CC(C(=O)c1ccccc1OCc1cscn1)c1ccccn1 +Cc1nn(-c2ccc(F)cc2F)c(C)c1C(=O)NCc1ccncc1 +O=C(CNC(=O)c1ccc2cncn2c1)NCc1ccccc1 +Cc1ncncc1NCc1ccccc1OC(F)F +N#Cc1ccc(C(=O)N2CCN(Cc3ccc(C(N)=O)cc3)CC2)cc1 +CC(c1nc2ccccc2c(=O)[nH]1)N(C)CCc1ccc(F)cc1 +COc1ccc(C)cc1NC(=O)c1nn(-c2ccccc2)nc1C +CC(=O)Nc1ccc(Br)cc1Br +COc1ccc2nc(C)c(C(=O)N3CCNC(=O)C3)cc2c1 +COC(=O)c1ccc(COc2nnc(-c3ccccc3)o2)o1 +O=S(=O)(Cc1nc(-c2ccsc2)no1)c1ncccc1Cl +Cc1cc(C(C)NC(=O)CCc2cccnc2)c(C)o1 +CC(NC(=O)c1cc(C(N)=O)cs1)c1cccc(N2CCCC2)c1 +CCS(=O)(=O)NCCn1ncc2c(N3CCCCC3)ncnc21 +CCOCCCCNC(=O)Nc1c(C)cc(C)cc1C +O=C(NCCC1CCC1)c1cc(N2CCCC2=O)ccc1Cl +CCOC(=O)Nc1ccc(Oc2cc(C)nc3ncnn23)cc1 +CCOC(=O)c1c(NC(=O)c2ccncc2F)sc(C)c1CC +CCCCCNC(=O)Nc1ccccc1CC(N)=O +Cn1ccc2c(C(=O)N3CCCS3(=O)=O)cccc21 +CCC(C)c1ccc(S(=O)(=O)NCc2cccnc2)cc1 +NC(=O)c1ccccc1NS(=O)(=O)c1ccc2c(c1)CCC2 +COc1ccc(CCSc2nnc(C3CC3)n2C2CC2)cc1 +Nc1ccc(-c2csc(=O)n2Cc2c(F)cccc2Cl)cc1 +CC(=O)Nc1ccc(NC(=O)COc2ccccc2)c(C)c1 +O=S(=O)(Cc1ccccc1C(F)(F)F)Nc1cn[nH]c1 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+CC(=O)NCCNC(=O)N(C)CCOc1ccccc1 +CCc1cccc(CC)c1NC(=O)Cn1cnc(C2CCC2)cc1=O +CCNc1nc(-c2csc(COC)n2)cs1 +Cc1ccn(CC(=O)Nc2ccc(C(=O)N(C)C)cc2)c(=O)c1 +CCC(NC(=O)N(CC)C(C)c1cccnc1)c1cc(F)ccc1F +Cn1cc(C#N)cc1C(=O)NC1CCCN(Cc2ccccc2)C1=O +O=C(NCc1ccco1)Nc1cc2c(cc1Cl)OCCO2 +O=C(CNc1c(F)cccc1F)Nc1ccc(F)cc1F +CCCCNC(=O)CC1NC(=O)c2ccccc2NC1=O +CC(C)(C)CC(=O)N1CCN(C(=O)c2cccc(F)c2)CC1 +Nc1nc(-c2ccccc2)cc(-c2nc3cccnc3[nH]2)n1 +CCn1ncc(-c2ccc(C)c(Cl)c2)c(N)c1=O +Cc1cccc(NC(=O)CNC(=O)c2cc3sccc3n2C)c1 +CCC(CC)(CC)CNC(=O)Nc1cnccc1C +CC1CN(C(=O)c2cc(F)cc(C#N)c2)CCC1(O)C1CCOCC1 +COC(=O)C1CC(O)CN1CC1=Cc2cc(Cl)ccc2OC1 +CSc1cccc(NC2CCCCNC2=O)c1 +CCc1nnc(NC(=O)c2cc3c(=O)c4ccccc4oc3o2)s1 +O=C(Cn1cnnn1)Nc1ccc(Oc2ccccc2)cc1 +CC(NC(=O)CCCC(=O)N(C)C)c1cccc2ccccc12 +CC(C(=O)N(C(C)C)C(C)C)N1CCN(C(=O)c2ccco2)CC1 +CC(C)C(=O)Nc1c(C(N)=O)cnn1-c1ccccc1 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)N(CC(N)=O)C(C)C +O=C(NCC#Cc1ccccc1Cl)c1ccc(=O)oc1 +Cc1cccc(N(CCC(N)=O)Cc2cccc(C(=O)N(C)C)c2)c1 +CC(C)(C)OCc1ccc(F)cc1C#CCCO +O=S(=O)(Nc1cn[nH]c1)c1cc(Cl)ccc1Cl +CCN(CCO)c1ncnc(Oc2ccc(C(C)C)cc2)c1N +Cc1cc(F)ccc1CN1CCN(C(=O)c2cccc(O)c2)CC1 +CN(C)S(=O)(=O)c1ccc(=O)n(CC(=O)c2ccccc2)c1 +Cc1ccc(C(=O)NCCc2ccc3c(c2)OCCO3)s1 +Cc1nc(CN2CCN(c3cc(C#N)c4ccccc4n3)CC2)no1 +O=C(COC(=O)Cc1ccccc1F)NCc1ccccc1 +Cc1cc(C)n2nc(SCC(=O)NCCC(C)C)nc2n1 +CC(=O)N1CCc2[nH]nc(-c3cccc(Cl)c3)c2C1 +CC(C)(C)c1ncc(NC(=O)COC2CCCCC2)cn1 +CC(=O)N1CCCN(c2cccc(Cl)c2C#N)CC1 +O=C(Nc1ccccc1C(=O)N1CCCC1)c1cccc(Cl)c1 +CN(CC1CC1)S(=O)(=O)c1ccc2oc(=O)ccc2c1 +COc1ccc(NC(=O)NC2CCCc3c2cnn3C)cc1 +Cc1cc(Sc2ccccc2)ccc1NC(N)=O +Cc1ccccc1OC(=O)CN1C(=O)CSc2ccccc21 +Cc1cc(Cl)ccc1OC(=O)CCC(=O)N1CCOCC1 +Cc1cc(N)c(-c2ccc(C(N)=O)o2)cc1Cl +CCOCC(=O)N1CCCC2(CC(OCc3cccc(C)n3)CO2)C1 +Cn1c(C(=O)OCC2CC(=O)N(C3CC3)C2)cc2ccccc21 +COC(=O)c1cc(C(=O)Nc2cccc(F)c2)ccc1F +O=C(NCCOc1ccc2c(c1)OCO2)Nc1nccs1 +O=C(NCc1ccccn1)C1CCN(c2ncnc3[nH]cnc23)CC1 +Cc1nc2ccccc2c(=O)n1-c1ccc(NC(=O)C(C)C)cc1 +CCc1ccccc1NC(=O)C1CC(=O)NC(C)=C1C(=O)OC +COc1ccc(C2(C(=O)NCc3ccnn3C)CCCC2)cc1 +CCOCCCNC(=O)C1CN(C(=O)c2cc(C)on2)C1 +Cc1cc(Cl)ccc1NS(=O)(=O)c1c(C)noc1C +CC(NC(=O)c1cc(C2CC2)[nH]n1)c1nc2ccccc2[nH]1 +CCn1nc(CC(C)C)cc1C(=O)NC1CCCC1C(N)=O +COc1cc(CCC(O)c2cccnc2)cc(OC)c1OC +CC(=O)Nc1ccc(O)c(C(=O)NCCCO)c1 +Cc1cccc(C(N)=O)c1NCC(=O)N1CCCCCC1 +Cc1nc(C)c(C(=O)OCc2nccn2Cc2ccccc2)s1 +Cc1cccc(C(=O)N2CCN(C(=O)c3cccs3)CC2)n1 +Cc1noc(COC(=O)CCSc2ccc(Cl)cc2)n1 +COCC(=O)N1CCCCC1c1nc(C)cc(Nc2ccccn2)n1 +O=C(CCc1ccc2c(c1)OCCO2)NCc1ncc[nH]1 +O=C(NCCNc1ncccn1)Nc1ccncc1 +CC(C)(C)OC(=O)N1CCCN(CCn2cncn2)c2ccccc21 +COc1ccc(CNC(=O)CCc2nccs2)c(C(F)(F)F)c1 +Cc1cc(C(=O)NCCNc2ncccc2C#N)c2[nH]ncc2c1 +COCCN(CC(=O)N(C)C)Cc1ccc(C)s1 +CCC(=O)Nc1cccc(NCC(=O)N2CCCCCC2)c1C +O=C(NCC1CCCO1)c1ccc(C(F)(F)F)cc1 +COc1cccc2c1N(S(=O)(=O)c1cccnc1)CCC2 +Cc1ccc2c(c1)CCCN2C(=O)c1csc(C)n1 +Cc1nnc(SCC(=O)NCC2CCCO2)n1Cc1ccccc1 +O=C1OC(C(=O)Nc2ccnn2C2CCCCC2)Cc2ccccc21 +CCOc1ccc(S(=O)(=O)N(C)CC(=O)NC2CC2)cc1Cl +CCOc1ccc(C(=O)Nc2nn3c(CC)nnc3s2)cc1 +CN(C)C(=O)c1cccc(NC(=O)c2ncccc2OCC(F)F)c1 +Cn1cc(C(=O)Nc2ccc3nn[nH]c3c2)c(C(C)(C)C)n1 +Cc1cc2n(CC(=O)Nc3ccc(C)c(C)c3)c(C)cc(=O)n2n1 +Cc1ccccc1OCCCC(=O)Oc1ccc2c(c1)OCCO2 +CCCCn1c(=O)[nH]c(=O)c2c1ncn2Cc1ccco1 +CC(=O)N1CCN(Cc2nc3ccc(C)c(C)c3[nH]2)CC1 +Cc1nnc(SCc2coc(-c3ccccc3)n2)n1N +COc1ccc(NC(=O)COc2ccc(-c3nnco3)cc2)cc1 +COCCNC(=O)CCCn1nc(C)n2c(cc3oc(C)cc32)c1=O +COC(=O)CC1Oc2ccccc2N(Cc2cnn(C)c2)C1=O +CC(C)(NC(=O)c1cc(-c2cccc(Cl)c2)on1)C(N)=O +O=C1CCCc2nc3nc(SCc4cccc(Cl)c4)nn3cc21 +Cc1ccc(CN(C)C(=O)c2cc(C3CC3)[nH]n2)o1 +c1cnc2c(SCc3cn4ccsc4n3)cccc2c1 +O=C(C1CC1)N(Cc1ccccc1)c1ccccn1 +CCN(Cc1cccc(NCc2ccccc2-n2cccn2)c1)C(C)=O +CNc1nc(SCC(N)=O)nc(N2CCOCC2)n1 +c1coc(-c2nnc3sc(-c4ccncc4)nn23)c1 +Cc1cnc(NC(=O)CCCc2nc3ccccc3[nH]2)s1 +CN(CCC(=O)N1CCC(CN2CCOCC2)CC1)c1ccccc1 +CC(CCSc1ccccc1)Sc1ncc(CO)n1C +CN(Cc1cccc(NC(=O)OC(C)(C)C)c1)CC(F)F +O=C(Cn1ncc2c1-c1ccccc1OC2)NCc1ccc(F)cc1 +COCC(=O)N1CCN(C(=O)NCCc2cccc(Cl)c2)CC1 +O=C(Nc1cccnc1)N(Cc1ccccc1)CC1CCOCC1 +CCc1nc(CN2CCN(Cc3csc(CC)n3)CC2)cs1 +CCOC(=O)CN(C(=O)C1CCOCC1)C1CC1 +COc1ccccc1CNC(=O)Nc1cccc(C(C)=O)c1 +CC1CCCCN1c1ccc(N)cc1-n1cnnc1 +CCC1CN(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)CC(C)O1 +Cc1cc(C)cc(-n2nnc(-c3nc(-c4cccs4)no3)c2N)c1 +Cc1sc(C(N)=O)cc1S(=O)(=O)NC(C)(C)CO +Cc1nc(-c2ccc(NC(=O)NC3CCC(C)CC3)cc2)no1 +CC(C)NC(=O)N1CCCN(S(=O)(=O)c2ccccc2)CC1 +Cc1cc(N(Cc2ccco2)C2CC2)n2ncnc2n1 +N#Cc1nnn(Cc2c(F)cccc2Cl)c1C1CCC1 +CCOC(=O)c1[nH]c(=O)[nH]c1COC(=O)c1ccco1 +O=C(CCc1nc(-c2ccc(Cl)cc2)no1)Nc1ccncc1 +CC(=O)c1cccc(NC(=O)N2CCC(O)(c3nccn3C)CC2)c1 +CCCCCCNC1=NS(=O)(=O)c2cc(C)ccc2N1 +OCCn1nc(CO)cc1-c1ccc(Cl)c(Cl)c1 +CCOC(=O)Cc1ccccc1NC(=O)NCc1ccc(F)cc1 +O=C(CNC(=O)C1CCOc2ccccc21)c1ccco1 +O=C(CN1C(=O)CSc2ccccc21)NCCO +CN(CCCOc1ccccc1)C(=O)C1CCC(=O)N1 +CCOC(=O)c1cccc(NC(=O)N(CC)CC)c1 +CC(C)N1C(=O)COC2CN(C(=O)C3CC3)CC21 +CC1CN(S(=O)(=O)c2ccc(-n3cnnn3)cc2)CC(C)O1 +NC(=O)c1n[nH]c2ccc(NCc3cccc4c3OCCCO4)cc12 +COCC1CCCN(C(=O)Cc2ccc(F)c(F)c2)C1 +COc1ccsc1C(=O)N1CCC(NC(=O)c2ccncc2)CC1 +COc1cc(-c2noc(-c3csc(-c4ncccn4)n3)n2)ccn1 +CC(C)n1ncc2c(C(=O)Nc3nc[nH]n3)cc(-c3ccccc3)nc21 +Cc1ccsc1CN(Cc1ccncc1)Cc1cccnc1 +COC(=O)c1ccc(C2NC(=O)c3ccccc3N2)o1 +COc1cc2c(cc1OC)CN(c1nc3ccccc3o1)CC2 +CC(CO)C(C)N1CC2=C(C1=O)C(c1ccccc1)NC(=O)N2C +CN(C)c1ccc(C(=O)NCC2(c3cccs3)CCOCC2)cc1 +O=C(NCCc1nc(-c2cccnc2)n[nH]1)NC1CCCCC1 +CC(=O)Nc1cccc(C(=O)OC(C)COc2ccccc2)c1 +O=C(Nc1cnc2ccccc2c1)NC1CCCCNC1=O +COCc1ccccc1CNC(=O)CCC(=O)N1CCOCC1 +Cc1ccc(C(C)C)c(OCC(=O)N2C(C)COCC2C)c1 +CN(C)c1nc(N)nc(COc2cc(Cl)ccc2Cl)n1 +CN(Cc1ccccc1)C1COc2ccc(F)cc2C1O +CS(=O)(=O)N1CCCCC1C(=O)NCCCOc1ccccc1 +OC(CCOc1ccccc1)CC1CCOCC1 +Cc1ccc2c(Cl)ccc(OCc3nnc(C)o3)c2n1 +C#CCN1CCCCC1C(=O)NCC(C)(O)c1cnn(C)c1 +O=C(OC1CCN(CC(F)F)CC1)c1cccc2ncccc12 +Cc1cccc(C)c1OCCC(=O)NC1(C(N)=O)CCCCC1 +N#CCC1CCCc2c1c(-c1ccccc1)nn2CCO +CCc1onc(C)c1NC(=O)NCCNC(=O)C1CC1 +Cc1cccc(C(=O)NCc2nccc(N(C)C)n2)c1 +CC(C)(C)OC(=O)NCCC(=O)Nc1ccc(C(F)(F)F)cc1 +COc1ccc(-c2nnc(SCC(=O)Nc3cn[nH]c3)o2)cc1 +COCC(=O)NCc1ccc(OCc2ccc(F)cc2)cc1 +O=C(COC(=O)c1cccs1)c1ccc2c(c1)OCCO2 +O=C(NCCS(=O)(=O)N1CCOCC1)c1cc(C2CC2)[nH]n1 +Cc1ccnc2nc(C(=O)NC(c3ccccc3)C3CCCC3)nn12 +O=C(NCCc1cn[nH]c1)c1sc2cccc(F)c2c1Cl +O=C1CN=C(c2ccccc2F)c2cc(OC(F)(F)F)ccc2N1 +CN(C)C(=O)CN(C)C(=O)CCn1c(=O)oc2ccccc21 +Cc1csc(NC(=O)c2ccc(-n3ccnc3C)nn2)n1 +COc1ccc(OC)c(C(=O)N2CCC(O)(C(F)(F)F)CC2)c1 +C=CCNC(=O)Nc1nc(-c2ccc3c(c2)OCCO3)cs1 +COC(=O)CN(Cc1ccc(F)c(F)c1)c1cc(C)nc2ncnn12 +Cc1nc(CNc2ccc(-n3cccn3)nc2)cs1 +O=C(CN1CCCCCC1=O)NCc1ccc(Cl)cc1 +Cc1cc(C(C)NS(=O)(=O)c2cc(C)sc2C)c(C)o1 +O=C(c1ccc(-n2cccn2)cc1)N1CCN(c2ccccc2O)CC1 +CC(=O)Nc1cccc(NC(=O)c2csc(NCC(C)C)n2)c1 +CC(=O)c1ccc(NC(=O)c2sc(N(C)C)nc2C)cc1C +Cc1ncsc1C(=O)NC(CN1CCCC1=O)c1ccccc1 +Cc1oncc1C(=O)N1CCOC2CCC1C2OCC1CC1 +COc1ccnc(C(=O)N2CCCCC2c2nc(C)cs2)c1 +CCNC(=O)N1CCC(Oc2nc3ccc(F)cc3s2)CC1 +N#CCCCOc1cccnc1NC(=O)Cc1ccc(F)c(F)c1 +O=c1cc(CO)occ1OCc1c(F)cccc1Cl +CC(C)n1nccc1NC(=O)c1c[nH]c2cccc(F)c12 +CC(CNC(=O)c1ccc(-n2ccnn2)cc1)c1ccc(F)c(F)c1 +CCCc1nc2c(N)cccc2n1CC(=O)NC1CCCC1 +COC(=O)c1c(C)nc(C)c2c(=O)n(CCN3CCOCC3)ccc12 +COc1ccc(C(=O)N2CC3CC(NS(C)(=O)=O)C2C3)c(C)c1 +CCn1nc(C)cc1C(=O)Nc1nc2c(s1)CCCC2 +Cc1cnc(C2NCCc3cc(Cl)c(Cl)cc32)cn1 +COc1ccccc1CC(=O)Nc1cnc(-c2cccnc2)nc1 +CCc1nnc(CNc2ccc(C(=O)NC(C)C)cc2)o1 +COCc1cccc(NC(=O)NC2(c3nc(C)cs3)CCCC2)c1 +O=S(=O)(c1cccs1)N1CC=C(c2c[nH]c3ccccc23)CC1 +O=c1[nH]c(=O)c2cc(S(=O)(=O)NCC3CC=CCC3)ccc2[nH]1 +CC(C)CC(=O)NCc1ccc(OCc2cccnc2)cc1 +CC1CN(c2ncnc3c2cnn3-c2cccc(Cl)c2)CC(C)O1 +Cc1noc(COCC(=O)Nc2ccc(Oc3ccccc3)cn2)n1 +CC(C)(C)Oc1ccncc1NC(=O)C1COc2ccc(F)cc2C1 +Cc1cc(C(=O)CNC(=O)CCc2ccccc2)ccc1F +C#CCOc1nc(C)nc2c1nnn2Cc1ccc(F)cc1 +Cn1ccnc1S(=O)(=O)C(c1ccc(F)cc1)c1ccc(F)cc1 +CS(=O)(=O)Oc1cccc2c(OS(C)(=O)=O)cccc12 +CCc1oc2ccccc2c1CN(C)C(=O)c1cc(C(N)=O)cs1 +CCC(=O)CSc1nnc(-c2cccnc2)n1Cc1ccccc1 +Cc1cc(S(=O)(=O)NC(CCO)C(C)(C)C)c(C)o1 +CN(Cc1nc2ccccc2s1)Cc1nc2ccccc2[nH]c1=O +Cn1cc(COC(=O)c2cccc(-c3ccoc3)c2)cn1 +Cc1cccc(NC(=O)N2CCCC2CO)c1Br +O=C(c1ccon1)N(Cc1ccccc1)c1ccccc1 +O=C1CCc2ccc(C(=O)NCCOc3ccccc3)nc2N1 +CCC(CC)CN(CCC#N)C(=O)c1ccc(O)c(Cl)c1 +COCc1nc(C(=O)NCCc2ccc(O)cc2)cs1 +CCCCCNS(=O)(=O)c1ccc(Cl)cc1N +CCN(CC)C(=O)CCC(=O)N1CC(C)OCC1c1ccccc1 +Cn1cc(C2CCCN2C(=O)c2csc(-c3ccccc3)n2)cn1 +O=C(CC1=CCCCC1)N1CCC(OCC2CC2)C2OCCC21 +CCCN1CCN(S(=O)(=O)N2CCN(C)CC2)CC1 +Cc1cccc(-c2[nH]ncc2CN2CCOC3(CCCC3)C2)c1 +CC1CCCCN1C(=O)c1ccc(N2CCCCC2=O)cc1 +O=C(NCCC(=O)N1CCCC1)c1ccsc1 +COCCS(=O)(=O)NC1(c2cccc(Br)c2)CC1 +Cc1cc(OCC(=O)NCC(F)(F)F)ccc1N +O=c1cc(CN(Cc2cccnc2)CC2CCCO2)[nH]c2ccnn12 +CC1CN(Cc2cnn(C)c2)CCN1CC(O)c1ccccc1 +CCC1CCCCC1NC(=O)NCC(C)CC(C)O +Cc1nc(C)n(CC2CN(Cc3ccc(C(N)=O)cc3)CCO2)n1 +CCOC(=O)C(N)Cc1c(OC)cc(O)cc1OC +Cn1cccc1C(=O)N1CCN(Cc2nc3ccccc3s2)CC1 +CC(NC(=O)c1cn2cccnc2n1)c1ccc2ccccc2c1 +CC(=O)NC1(C(=O)NC2CCCC2)CCCCC1 +Cc1nc(NC(=O)c2ccc(N3CCCCC3=O)cc2)sc1C +Cc1ccc(F)cc1C(=O)OCc1nnnn1-c1ccccc1 +Cc1ccc2nnc(-c3ccc(OC(C)C)c(N)c3)n2c1 +CC(C)CN1CC(C(=O)N2CCCCC2CCO)CC1=O +NC(=O)NCc1ccc(C(=O)Nc2ccc(-n3ccnc3)cc2)cc1 +CCSc1nnc(N)n1CCOc1ccc(Cl)cc1 +CCc1nn(-c2cc(Oc3ccccc3C)ncn2)c(N)c1C(N)=O +O=C(C1CCCC1)N1CC(S(=O)(=O)NCCN2CCOCC2)C1 +Cc1cc(C)n(-c2ccc(CC(=O)N3CCN(CCO)CC3)cc2)n1 +COc1cc(CCC(=O)N2CCC2)ccc1OCC(F)(F)F +COCCN1C(=O)CCC2C1CCN2C(=O)Cc1cccc(F)c1 +CC(=O)Nc1ccc(-c2nn3c(C)nnc3s2)cc1 +CCOc1ccc(NC(=O)CS(=O)(=O)c2ccccc2)cc1 +O=C(c1ccco1)N1CCC2(CC1)Nc1cccnc1-n1cccc12 +Cc1cc(C)c(C(=O)NC2CCN(c3ccc(C#N)cn3)CC2)c(C)c1 +O=C(NCc1ccnc(-n2cccn2)c1)NC1CCCCC1 +CS(=O)(=O)NCCNC(=O)N1CCCC1Cc1cccc(F)c1 +C#CCNC(=O)c1ccccc1NCC(=O)Nc1ccc(CC#N)cc1 +CC1CCCN(C(=O)Cc2n[nH]c(=O)c3ccccc23)C1 +Cc1ccncc1NC(=O)NCc1nccn1C(F)F +CC(=O)NC(C)C(=O)N1CCN(CC(=O)N2CCCCCC2)CC1 +Cc1ccc(C#N)c(=O)n1CC(=O)Nc1ccccn1 +CCC(=O)c1ccc(OC(=O)C(C)n2c(=O)oc3ccccc32)cc1 +Cc1ccc(C2COCCN2Cc2nc(-c3ccccc3)cs2)o1 +Cc1cc(Br)ccc1OCC(=O)N1CCC(=O)CC1 +CCc1cc(CNc2nc3c(cc2C(N)=O)CCC3)on1 +CC(C)CS(=O)(=O)N1CCCC1CS(=O)(=O)c1ccccc1 +CCCCn1c(N)c(N(C)C(=O)c2cc(C)oc2C)c(=O)[nH]c1=O +Cc1nc2c(nc3c(Br)cc(F)cn32)c(=O)[nH]1 +CCC(CCO)NC(=O)Nc1cccc(Cl)c1C +O=C(CCn1ccccc1=O)NCc1ccccn1 +CCCCC(=O)NC(C)c1cc(OC)c(OC)cc1C +Cc1ccc(-n2nnc(C(=O)Nc3ccc(C#N)cc3)c2C)cc1 +COCc1ccccc1CNC(=O)c1nc2ccccc2c(=O)[nH]1 +NC(=O)Nc1ccc(-c2csc(Nc3ccccn3)n2)cc1 +CCOC(=O)CCC(C)NC(=O)c1cc2c(C)cc(F)cc2[nH]1 +CCOCC(=O)Nc1ccccc1C(=O)N1CCOCC1 +COc1cc(OC)cc(C(=O)OCc2nc(N)c3ccccc3n2)c1 +CN(Cc1ccccc1F)C(=O)CCCn1c(=O)oc2ccccc21 +COC1CN(Cc2scnc2C)C2CCCOC12 +O=C(NCc1cccc(F)c1)NCc1nnc2n1CCCC2 +CNC(=O)c1ccc(N)c(OCc2ccc(Cl)cc2)c1 +CCc1nnc(CN(C(=O)c2cccc3nccnc23)C(C)C)o1 +O=C(c1ccnc(OCC(F)F)c1)N1CCC(n2ccnn2)CC1 +Nc1cc(NC(=O)CCCn2cncn2)ccc1Cl +CCN(C(=O)c1cc(OC)ccc1O)C(C)COC +Cc1c(NS(C)(=O)=O)cccc1C(=O)NC(C)(C)C +NC(=O)C1Cc2ccccc2CN1C(=O)C1CC2CCC1C2 +CN(CC1(CO)CCC1)c1nccc(-c2cnn(C)c2)n1 +COC(=O)CC(NC(=O)c1ccncc1)c1ccccc1Cl +CCc1nc(CC(=O)Oc2cccc(C(N)=O)c2)cs1 +CC(=O)NCCCNC(=O)Nc1c(C)cccc1C +CC1CC(C)CN(C(=O)CN2CCN(C(=O)c3ccccn3)CC2)C1 +COC(=O)CN1CCCC(c2nnc3n2CCCCC3)C1 +CC(NC(=O)C1Cc2ccccc2O1)c1cccs1 +O=C(c1ncccc1Cl)N1CCN(c2ccccc2F)CC1 +CCCCS(=O)(=O)N1CCN(c2cc(OC)nc(OC)n2)CC1 +CCN(CCCNS(N)(=O)=O)c1ccccc1 +O=C(NCc1cscn1)c1cccnc1OCC(F)(F)F +COc1cc(C#N)ccc1OC(=O)COc1ccc(C)cc1C +Cc1sc2ncnc(Oc3cccc(C(=O)NCCO)c3)c2c1C +Cc1noc(C)c1CC(=O)NCc1cccnc1OCC(F)(F)F +O=C(NC1CCCCC1)C1CCCN1C(=O)c1cccc2ccoc12 +Cc1csc(C(C#N)C(=O)COc2ccc3ccc(=O)oc3c2)n1 +CCOc1ccc(N2CC(c3nnc(N)o3)CC2=O)cc1 +Cc1noc(C)c1C(=O)NCCc1cccs1 +CCCN(CC1CC1)C(=O)Nc1ccc(NC(=O)OC)cc1 +COCC1(NC(=O)Nc2ccccc2OC)CCCC1 +Cc1cccc(N)c1C(=O)Nc1cccc(C#N)c1 +CC(Oc1ccc(Cl)cc1)C(=O)N1CCN(CC(N)=O)CC1 +Cc1ccc(CC2CN(CCO)c3cc(O)ccc3O2)cc1 +CCc1cccc(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 +CCCCNc1nc(C(C)C)nc(OCC)c1N +CN1CCN(C(=O)c2cnc3ccccc3c2C(F)(F)F)CC1 +CCNc1c(N)cc(C(=O)OCC)cc1Br +Cc1ccoc1C(=O)N1CC2CC3CC(C2)CC1C3 +O=C(CNS(=O)(=O)c1cccc(Cl)c1)Nc1cccnc1 +O=C(NCc1cn[nH]c1-c1ccccc1)c1ccc(C(F)(F)F)cc1 +COc1cccc(CNC(=O)NCC2CC=CCC2)c1 +COc1ccc(NC(=O)c2cc3ccccc3c(=O)[nH]2)cc1 +Cc1nc(-c2cccnc2)cc(N2CCC(=O)CC2)n1 +Nc1nonc1C(=O)Nc1cccc(Cl)c1F +CS(=O)(=O)NCCCNC(=O)N1CCc2ccccc21 +Cc1ccc(C(=O)NCCc2ccc(OC(F)(F)F)cc2)c(=O)[nH]1 +COCc1ccc(C(=O)NCC(C)N2CCOCC2)o1 +COc1ccc(C(=O)NCC(=O)n2nc(C)cc2C)cc1 +Cc1cc(C(=O)Nc2cccc(S(=O)(=O)N3CCCCC3)c2)no1 +Nc1cnn(CCCCc2ccc3ncoc3c2)c1 +CCN(CC(C)C#N)S(=O)(=O)c1cn[nH]c1C +O=C(NC1CC1)c1cc(NC(=O)C2CCCO2)ccc1Cl +Cc1cc(C)c(NC(=O)CN(C)C(=O)NC(C)C)c(C)c1 +Cc1nnc(NC(=O)c2nccc3cccc(N)c23)s1 +O=C(Nc1c[nH]ccc1=O)c1ccnc(OCc2ccccc2)c1 +OCC1CCCCCC1Nc1nnc(-c2ccccn2)s1 +Cc1nnc(SCC(=O)N2CCc3ccccc3C2)n(N)c1=O +O=S(=O)(Cc1csc(NC2CCOCC2)n1)c1ccccc1 +Cc1ccc(-c2cc(-c3ccccc3F)nc(N)n2)o1 +CNC(=O)c1cccc(CN(C)C2CCCc3nc(C)sc32)c1 +CC(C)c1cccc2c1OCC(N1CCC(=O)CC1)C2O +COC(=O)C1C(C)=CCN1S(=O)(=O)c1ccc(OC)cc1 +CC(OCC(O)CNC(=O)c1cc(F)cc(F)c1)c1ccccc1 +COc1ccc(CCC(=O)NC(C)(C)C#N)cc1OC +COc1ccc(C)cc1-n1nnnc1SCC(=O)NC1CCCC1 +O=C1CCOc2c(Cl)cc(C(F)(F)F)cc21 +CCC(C)n1nccc1NC(=O)Cc1ccc(O)cc1 +CCC(CC)(CC)NC(=O)c1cc(S(=O)(=O)N(C)C)oc1C +Cn1cc(C2CCCN2c2ncnc3[nH]ccc23)cn1 +Cc1cccc(OCc2nc3cc4c(cc3[nH]2)OCCO4)c1C +CC(=O)NCC1CCCN(C(=O)c2c[nH]nc2-c2ccccc2F)C1 +Cc1cnn(CCC(=O)NC(C)c2ccc(NC(=O)C3CC3)cc2)c1 +Cc1cccc(C(C)C)c1NC(=O)COC(=O)c1ccc[nH]c1=O +Cc1noc(NC(=O)c2ccn(-c3cccc(Cl)c3)n2)n1 +O=C1CCc2cc(OC(=O)Cc3ccc(F)cc3)ccc2N1 +CCC(C)NC(=O)COC(=O)c1ccc2c(c1)nc(C)c(=O)n2CC +Cn1ccc(NC(=O)c2cc3c(Cl)cccc3n2C)n1 +COCc1ccc(CNC(=O)CNC(C)=O)cc1 +COc1ccc(COC(=O)c2ccc(NC(N)=O)cc2)cc1F +Nc1cccc2c1oc(=O)n2Cc1ccc(Cl)cc1 +O=C(Cc1coc(-c2cccs2)n1)N1CCc2cc(F)ccc2C1 +CCNc1cnc(C(C)C)nc1C(=O)N(C)C1CC1 +CC(=O)N1CCC(C2NCCc3c(O)ccc(F)c32)CC1 +CC(=O)Nc1ccc2c(c1)C(c1ccc(C)nc1)NCC2 +Cc1ccn(CCOc2ccccc2F)c(=O)c1C#N +O=C(c1ccc(Br)cc1)N(Cc1ccsc1)C1CC1 +CCOC(=O)C1=C(C)NC(=O)CC1c1ccc(C#N)cc1 +Cc1cc(C)cc(NC(=O)c2c(C)oc3ncn(C)c(=O)c23)c1 +O=C(Nc1cccc(Cl)c1)c1ccn(-c2ccccc2)n1 +CCOC(=O)CCC(=O)Nc1ccc(F)c(Cl)c1 +Cc1ccc(CNC(=O)NC2CCC3(CC2)OCCO3)cc1 +CCCOc1cc(C)c(C)cc1S(=O)(=O)NCC(C)O +Cc1ccc(C(=O)NC2CC2)cc1NC(=O)CN1CCCCC1=O +O=C(Nc1ncccc1F)c1ccc(Br)cn1 +C=CCCOC(=O)c1cn(C)nc1-c1cccs1 +CN(Cc1cnn(C)c1)c1nc2ccccc2s1 +Cc1noc(COC(=O)c2cc(C)n(C(C)C)c2C)n1 +CCOC(=O)c1c(C)[nH]c(C(=O)NCC2CC2C)c1C +O=C(Cc1ccc(-n2cccc2)cc1)Nc1ccccc1F +N#Cc1ccc(OCC(=O)Nc2sccc2C(N)=O)cc1 +CCCC(C)N1CC2(CCN(C(=O)c3cccc(C)n3)CC2)OC1=O +Cc1nc(C(C)(C)NC(=O)c2ccc(F)c(F)c2)sc1C +Cc1ccc(CNC(=O)c2cn(-c3ccccc3)nn2)cc1 +COc1ccc(C(=O)OCC(=O)N2CCCCCC2)c(OC)c1 +Cc1cn(Cc2ncnn2C2CCCCC2)c(=O)[nH]c1=O +CSc1cccc(NC(=O)Cn2nc3c(cc2=O)CCCC3)c1 +CCc1noc(CN(C)Cc2cnc(-c3ccc(C)o3)s2)n1 +COc1ccccc1C(=O)NCCNC(=O)c1ccc(C)nc1 +CCOC(=O)c1cc(N)cc2nc(-c3ccccc3Cl)oc12 +Cn1cn[nH]c1=NC(=O)c1ccn(-c2ccccc2F)n1 +Nc1ccc2c(C(=O)NCc3cccnc3)nccc2c1 +COc1ccc(CCS(=O)(=O)NCc2cc(C)oc2C)cc1 +CCOc1ccc(NC(=O)c2ccc(Cn3ccnc3)cc2)c(C)c1 +O=C(CCCO)N1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1ccc2ncc(C(=O)N3C(C)CCC3C)n2c1 +Cc1cccc(S(=O)(=O)CC(=O)NCc2ccccc2C)c1 +Cc1[nH]ncc1CCCNC(=O)c1ccc(=O)n(-c2ccccc2)n1 +CN1CCC(N2CCCc3c(NC(=O)OC(C)(C)C)cccc32)C1=O +COCc1cc(NCc2cc3cc(OC)ccc3[nH]2)n2nccc2n1 +COc1ccc(-c2cc3nc(C)cc(C)n3n2)cc1OC +O=C(c1cnccn1)N1CCCC(CCc2ccc(F)cc2)C1 +Cc1ccc(NC(=O)N2CCc3ccccc3C2)nc1 +CCc1cc(C(=O)Nc2c(C)nn(-c3ccccc3)c2C)[nH]n1 +CC(Oc1ccc(C(C)C)cc1)C(=O)Nc1ccc(C(N)=O)cc1 +CCCC(=O)c1ccc2c(c1)N(CC)C(=O)C(C)(C)O2 +CN1CCOc2ccc(NC(=O)CC(C)(C)C)cc2C1=O +CCc1n[nH]c(SC(C)C(=O)Nc2ccccc2)n1 +O=C(NCCc1ccccc1F)NCC1CC=CCC1 +Cn1cccc1C(O)CNC(=O)Cc1cccc2ccccc12 +CCn1ncc(CNc2ncnc3c2NC(=O)CN3)c1C +Cc1nn(-c2cccc(Cl)c2)c(C)c1C(=O)NCC(C)C +CCC(C)(C)NC(=O)C(Sc1nc(C)cc(N)n1)C(C)C +O=C(c1ccoc1)N1CCC2CC(c3nccs3)OC2C1 +CN1C(=O)COc2ccc(-c3nc(C4CC4)n[nH]3)cc21 +CC(NC(=O)c1cc2ccccc2nc1N1CCCC1)C(N)=O +CCOC(C)c1nc(CN2CC(C)OCC2C)cs1 +CCOC(=O)c1ccc(-c2cc(N)ccc2OC)o1 +CCOC(=O)C1CCCN1C(=O)Cc1cccnc1 +CC(C)c1noc(CN2CCc3ccccc3C2)n1 +CC(NC(N)=O)C(=O)N(Cc1cccs1)Cc1cccs1 +CC(C)(C)c1ccc(-c2nc(-c3cc(N)cc(N)c3)n[nH]2)cc1 +CCOC1CCCN(C(=O)c2ncccc2O)C1 +CC(=O)c1cccc(NC(=O)C2CCN(C(=O)OC(C)(C)C)CC2)c1 +CN(C)C(=O)N1CCN(c2cnn(C)c(=O)c2Cl)CC1 +Cc1ccc(N2CC(Nc3nccc(-c4cccnc4)n3)CC2=O)cc1 +CCC1CCC(NC(=O)c2ccc(-n3ccnn3)cc2)CC1 +CC(=O)Nc1ccc(Cl)c(NC(=O)NCCO)c1 +O=C(Cn1cnc2ccccc21)NCCc1ccsc1 +CCC(CC)N(CCO)C(=O)c1c(F)cccc1F +C=CCNC(=O)CCCC(O)c1c(C)cc(C)cc1C +NC(=O)CNC(=O)Cn1cc(C(F)(F)F)ccc1=O +CCCNC(=O)N1CCN(c2cc(C#N)ccn2)CC1 +CCOC1CC(N(C)C(=O)NCc2ncn(C)n2)C1(CC)CC +O=C(Cc1c(F)cccc1Cl)N1CCc2sccc2C1 +CC(C)C(=O)N1CCC(C(=O)OCc2cc(C#N)ccc2F)CC1 +CCc1cc(C#N)c(NC(=O)Cc2cccc(C(=O)OC)c2)s1 +CCc1ccccc1OC(=O)CCc1c(C)nc2c(C#N)cnn2c1C +CC1CCN(S(=O)(=O)NCc2cccnc2-n2cncn2)CC1 +CC1CCCC(OCc2cccc(NC(=O)C3CCC(=O)N3)c2)C1 +Cc1cc(-n2cnnc2)cc(C)c1NC(=O)c1cccc2ccccc12 +COCC1(C(=O)NCc2csc3c2CCCC3)CCC1 +CCN(C(=O)CNc1cccc(NC(=O)C(C)C)c1)c1ccccc1 +CN(C)C(=O)C1CCCN1C(=O)Cc1cccc(OCC#N)c1 +CC1NC(=O)COC12CCN(C(=O)c1ccc3[nH]ccc3c1)CC2 +CC(CNc1ccccc1)NC(=O)c1cc2ccccc2[nH]1 +CCCn1c(SCc2cc(C)on2)nc2ccccc2c1=O +CC(NC(=O)Cn1nnc(-c2ccccc2)n1)c1ccc(F)cc1 +CCOC(=O)c1c(NCC(C)C)sc(C(C)=O)c1C +CCC(C)(C)NS(=O)(=O)c1ccc2c(c1)OCCO2 +CCCOC(=O)CSc1nc(C)c(C)c(C)c1C#N +Cn1c(=O)c2c(ncn2CC(=O)NC(C)(C)C)n(C)c1=O +COc1cccc(NC(=O)NCC2(O)CCCc3ccccc32)c1 +CCC(CC#N)NS(=O)(=O)c1c(C)nn(C)c1C +Cc1ccc2c(c1F)CCNC2c1cncc(F)c1 +COCCN1CCCC2(CCN(c3ccc4ccccc4n3)C2)C1=O +COc1ccc(CC(=O)Nc2ccc3nc(C)sc3c2)cc1C +CC(=O)Nc1nc2ccc(NC(=O)Cn3cnnn3)cc2s1 +Cc1noc(C)c1-c1ccc(-c2ncc(O)cn2)cc1 +CC(O)C(=O)N1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +Cc1ccc(C(=O)N(C)C(C#N)c2ccc(C)cc2)cc1 +COc1ccc(F)cc1C(=O)Cn1nc(C)c(C)c(C#N)c1=O +N#Cc1cccc(NC(=O)N2CCc3sccc3C2)c1 +Cc1cc(C(=O)N2CC(=O)N(c3ccc(Cl)cc3)CC2C)[nH]n1 +CC(=O)Nc1cc(C(=O)NCCCCn2ccccc2=O)ccc1F +Cc1ccc(-c2nc(C(=O)N(C)CC(N)=O)cs2)cc1 +O=S(=O)(CCn1cc(C2CCOC2)nn1)N1CCCC1 +Cc1ccc(CN2CCN(C(=O)c3ccccc3)CC2)cc1 +CSc1ccc(Nc2ncccc2S(N)(=O)=O)cc1 +CN(C(=O)Cc1c(F)cccc1F)C1CCN(c2ccccc2)C1=O +O=c1[nH]c(=O)n(C2OCC(O)C(O)C2O)cc1F +CCN1CC(C(=O)N(C)c2ccc(C)cc2)CC1=O +Cc1nc(COc2ccc(C(=O)Nc3nccs3)cc2)no1 +Cc1nnc2sc(NC(=O)c3ccc(Cl)cc3)nn12 +O=C(NCc1nc(-c2ccco2)n[nH]1)Nc1ccc(F)cc1 +NS(=O)(=O)c1ccc(CNC(=O)c2ccc(Cl)cc2O)cc1 +Cc1cccc(NC(=O)CNc2cccc(C#N)c2)c1 +COCCN1CC(C(=O)Nc2ccc(C)cc2F)CC1=O +CCC1CCC(NC(=O)COc2ccc(C(C)=O)cc2)CC1 +Cc1ccc(NC(=O)CSc2nnc(C)n2N)cc1C +CN1CCN(C(=O)Nc2cccc(Br)c2)c2cccnc21 +CNC(=O)c1cc(NC(=O)C2CC3C=CC2C3)ccc1F +Cc1ccccc1C(=O)NCc1noc(Cc2ccccc2)n1 +C=CCCC(=O)Nc1ccc(COC(=O)N2CCOCC2)cc1 +CC1COCCN1S(=O)(=O)c1sccc1Br +CCOCC1CN(C(=O)CC2C=CCC2)Cc2cnn(CC)c21 +CC(=O)Nc1ccc(C(=O)Nc2ccc(C)cc2F)cc1 +COC(=O)CC(N)C(=O)c1ccc(CC(C)C)cc1 +CN(C)S(=O)(=O)c1cccc(COc2ccc(F)c(F)c2)c1 +CN(CC1CCCCC1)C(=O)CN1CCOC(C)(C)C1 +CCOc1cccc(C(=O)NCc2ncc(-c3ccccc3)o2)c1 +Cc1ccc(C)c(NC(=O)N2CC3CCC(C2)N(CC2CC2)C3=O)c1 +CCOc1cc(C(=O)Nc2ncc(C)s2)ccc1OC(F)F +CCn1c(C)cc(C(=O)NCCNC(=O)C(C)C)c1C +O=S(=O)(Nc1cccc(F)c1)c1ccc2c(c1)CCN2 +Cc1cccc(NCc2ccc(F)cc2F)c1C(N)=O +O=C(CCc1cccc(F)c1)N1CCC(CN2CCOCC2)CC1 +O=C(NCC1(O)CCOCC1)NCC12CC3CC(CC(C3)C1)C2 +COc1cc(CNC(=O)N(C)CC2CCCC2)ccn1 +Cc1cccc(CNc2cnn(CC(F)(F)F)c2)c1 +CCn1c(-n2nc(C)cc2C)nc2c1c(=O)n(CC(N)=O)c(=O)n2C +COc1nn(C)cc1C(=O)NCCn1ccc(-c2ccncc2)n1 +COCC(C)NC(=O)Nc1ccccc1C(=O)N(C)C1CCCCC1 +O=C(CSc1nc(Cc2cccs2)n[nH]1)NCC(F)(F)F +CCCc1nc(C(=O)NCc2ccccc2Cn2cccn2)cs1 +CN(CC(=O)NC1CCOc2ccccc21)S(C)(=O)=O +CNC(=O)C1(NC(=O)c2nc(-c3ccco3)sc2C)CCCCC1 +COc1ccc(NC(=O)c2ccc(-n3nncc3C)cc2)c(OC)c1 +Cc1cccc(NCC(=O)N2CCCCC2)c1C(N)=O +Cn1cc(NC(=O)Nc2ccc(F)cc2)cc(Br)c1=O +Cc1cc(C)cc(CS(=O)(=O)c2nnc(N(C)C)s2)c1 +Cc1ccc(-c2cc(NC(=O)c3ccco3)on2)cc1 +Cc1ccc(NC(=O)c2ccc(O)c(Cl)c2)cc1S(C)(=O)=O +COC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1ccc(C)o1 +CN(C)c1ccc(-c2ccn(C)c(=O)c2C#N)cc1 +CC(=O)Nc1cc(NCC(=O)NC(C)C(C)C)ccc1C +CCc1nnc(CNc2cc(OC)ccc2F)o1 +CCn1nnc2cc(-c3noc(C4CCC4)n3)ccc21 +O=C(CSc1ccccn1)NC1CCCc2ccccc21 +Cc1nc(S(=O)(=O)NCCC(=O)NCc2ccsc2)cn1C +CCN(Cc1cccc(NC(=O)NCC(=O)NC(C)(C)C)c1)C(C)=O +Fc1cccc(Cl)c1-c1nccn1CCc1ccncc1 +O=C(NCCNC(=O)c1scnc1C1CC1)c1ccccc1O +Cn1nnc(-c2ccc(NC(=O)NCCN3CCNC3=O)cc2)n1 +CC(C)CCNC(=O)c1nc2ncc(Br)cn2n1 +O=C1C(=O)N(Cc2cccc(Br)c2)c2cc(F)ccc21 +COC(=O)c1cc(CN2CCN(c3ccc(O)cc3)CC2)c(C)s1 +CN(C(=O)NCc1ccccc1-n1ccnc1)C1CCC1 +CC(=O)c1ccc(NC(=O)C2CCCOC2)cc1C +COc1ccc(C)nc1NC(=O)Cc1ccc(F)c(F)c1 +Cc1ccc(-c2ccc(=O)n(CC(=O)NCc3ccco3)n2)cc1C +Cn1ccc2c(C(=O)N(CCC(N)=O)c3ccccc3)cccc21 +CCOC(=O)c1cn(-c2cc(SCC#N)ncn2)nc1C +CC(=O)N1CCC(NC(=O)CNC(c2ccccc2C)C(C)C)CC1 +O=C(Nc1ccc2ccccc2n1)c1ccc(=O)[nH]c1 +O=C(Nc1ccccc1Cl)c1cccc(CN2CCOCC2)c1 +CC1CCN(C(=O)C2CN(C(=O)c3c[nH]c4ccccc34)C2)CC1 +O=C(Nc1nc(Cc2ccc(F)cc2)n[nH]1)c1cccnc1 +O=C(c1ccccn1)N1CCN(c2ccccc2O)CC1 +Cc1ccc2cccc(C(=O)N3CCc4ncncc4C3)c2n1 +CCc1cccc(NC(=O)CC(C)n2cccn2)c1 +CC(C)(C)OC(=O)NCC(=O)Nc1ccc2c(c1)COC2 +CS(=O)(=O)c1ccc(Cl)c(NC(=O)c2ccc(F)cc2)c1 +NC(=O)C1Cc2ccccc2N1C(=O)c1ccc(F)nc1 +CC(C)Oc1cccc(C(=O)C2CCCN(C(=O)c3ccoc3)C2)c1 +CNC(=O)COc1ccc(S(=O)(=O)N2CCCCC2)cc1 +Cc1nc2c(s1)CN(S(=O)(=O)c1ccc3c(c1)OCO3)CC2 +Cc1ccc(NC(=O)Cc2c(C)nn(C)c2C)cc1F +CCc1cc(NCCCO)n2c(nc3ccccc32)c1C#N +Cc1cc(C(=O)Nc2nc3c(C)cc(Cl)cc3s2)on1 +Cn1ncc2c1ncn1nc(-c3ccc(Cl)cc3Cl)nc21 +C#CCOC(=O)C1CCN(S(=O)(=O)CC)CC1 +Cn1cc(-c2nc(COc3nc(C(C)(C)C)no3)cs2)cn1 +Cc1ccc(SCCNC(=O)Cc2ccc3c(c2)OCCO3)cc1 +COCCNC(=O)c1cc2sc3ccccc3c2s1 +CN(Cc1ccc(F)c(F)c1)C(=O)Nc1ccc(CC#N)cc1 +Cc1ccc(C(NC(=O)Nc2cnn(C)c2)c2ccccc2)cc1 +CCNC(=O)c1ccc(C)c(NC(=O)c2scnc2C2CC2)c1 +Cc1ccc(CCC(=O)N2CCCC2C(=O)NC2CC2)cc1Cl +CN(CCC#N)C(=O)Nc1ccc(OCC(F)(F)C(F)F)nc1 +O=S(=O)(Cc1ccc(Cl)cc1)NCCc1cnccn1 +CCC1CCCCN1c1ccc(S(=O)(=O)CC)c(N)c1 +CNc1ncnc(Oc2ccc(Cl)c(C)c2)c1N +COc1ccc(F)cc1NCc1nc2ccccc2n1C +CN(C)c1ccc(F)c(C(=O)NC2CCCC2)c1 +CCC(C(=O)Nc1cc(Cl)ccc1C)n1c(N)nnc1SC +CCCC(=O)N1CCC(C(=O)Nc2ccccc2C(=O)C(C)C)CC1 +CCN(C(=O)COc1ccc2c(c1)CCC(=O)N2)c1cccc(F)c1 +COc1ccc2c(c1)CC(NCc1cccc(NC(C)=O)c1)CC2 +C=CCc1ccccc1OS(=O)(=O)c1cn(C)c(=O)n(C)c1=O +Cc1ccc(C)c(NC(=O)NCc2ccnn2C)c1 +C=CCn1c(-c2ccc(OC)cc2)cn2cc(C(=O)NC)nc2c1=O +CCc1nc(C)c(C(=O)N2CCC(c3sccc3C)C(O)C2)o1 +CCc1nc2cc(F)c(F)cc2n1CCOc1cccc(N)c1 +COc1ccc(C(C)=O)c(OC(C)C(=O)NC2CC2)c1 +Cc1cc(C(=O)N2CCOc3c(Cl)cccc32)[nH]n1 +Cc1cc(NC(=O)N(Cc2cccc(O)c2)C2CC2)on1 +CC(C)Cn1cc(CCNC(=O)c2ccco2)c2cccnc21 +OCc1sc2ccccc2c1CN1CCOCC1 +Cc1ccccc1OCCCC(=O)N(C)c1cccc(C#N)c1 +Cc1ccccc1-n1ccnc1SCC(=O)NCc1cscn1 +COc1cccc(CN2CCOC(C#N)C2)c1OC +COc1nc(NCC(C)C#N)nc(NC(C)C)n1 +CCCNC(=O)NC(C)CCc1ccc(O)cc1 +Cn1ccc(C(NC(=O)CC(O)c2cccc(F)c2)C(F)(F)F)c1 +Cn1cc(CNC(=O)c2cc(F)c(F)cc2Cl)cn1 +CC1CC(Sc2nnc(C3CC3)n2C2CC2)C(=O)O1 +Cc1ccccc1OCCSc1nnc(Cn2cncn2)o1 +OCCCc1nc2ccccc2n1CCOc1ccccc1 +COc1ccccc1C(=O)N1CCC(C(N)=O)CC1 +CC(=O)c1ccc(Oc2ccc(C(=O)N3CCC(O)C3)cc2)cc1 +CCOC(=O)C1C(c2ccccc2)NC(=O)NC1(O)C(F)(F)F +O=c1[nH]c(CN(CC2CCCO2)CC2CCCO2)nc2ccccc12 +Cc1ccc2cc(C)c(SCC(=O)NCc3ccco3)nc2c1 +Cc1ccc(C(=O)Nc2cnc3oc(-c4ccccc4)nn3c2=O)cc1 +O=C(CNC(=O)c1csc2ncccc2c1=O)NC1CCCC1 +Nc1cc2c(cc1NC(=O)Cc1ccc(F)cc1)OCCO2 +O=C(C1C=CC=N1)N1CCC(c2ccc3ccccc3c2)C(O)C1 +CC(C)N(C(=O)Cc1csc(C(C)(C)C)n1)C(C)C +C#CCOC(=O)c1ccc(N)c(OCC(=O)NC)c1 +COC1CCCC1NS(=O)(=O)c1ccc(Cl)cc1N +O=C(CNc1cc(F)ccc1F)Nc1ccccc1F +Cn1cc(Br)cc(Br)c1=O +COc1nc2ccccc2cc1CNc1cccc(-n2cnnc2)c1 +O=C(NCCCC1CCCC1)NCc1ccccn1 +Nc1c(-c2nc3ccccc3[nH]2)c(-c2ccco2)nn1CCO +O=C(NC1CC1)C1CN(Cc2ccc(-c3ccccn3)cc2)CCN1 +CCC(O)Cn1nc(C2CCCC2)nc1-c1ocnc1C +CC(Cc1ccc(O)cc1)NC(=O)N1CC(C)OC(C)C1 +C=CCN(CC=C)C(=O)CSc1nncc2ccccc12 +Cc1cc(C)cc(C(=O)Nc2cnn(C3CCOCC3)c2)c1 +CN(C)S(=O)(=O)c1ccc(SCC(O)c2ccccc2)nc1 +CCC(Nc1nnc(C(C)(C)C)o1)c1ccnn1C +NC(=O)c1csc(C(=O)N(Cc2ccco2)c2ccc(F)cc2)c1 +CC(C)C(=O)Nc1ccc(S(=O)(=O)NCCc2ccoc2)cc1 +CN(C)c1cccc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)c1 +CC(C)CC(=O)N1CCN(Cc2cccnc2)CC1 +OC(c1ccccc1)C(Cl)(Cl)C(F)(F)F +CCCCOCC(=O)N1CCC2(CCOCC2)CC1 +CN(CC1(O)CCCC1)S(=O)(=O)N1CCCCCC1 +NC(=O)c1cccc(CNCCc2cccc3ccccc23)c1 +COC1CCCN(Cc2cnc3ccc(Br)cn23)C1 +NC(=O)c1ccc(C(=O)Nc2ccc(F)c(Cl)c2)cn1 +COC(=O)c1sc(NC(=O)C2CC2c2ccco2)nc1C1CC1 +Cc1cccc(C)c1NC(=O)CSc1ncccc1C#N +COCC(NC(=O)C(C)(C)c1ccc(F)cc1)C(N)=O +COc1ccc(CNS(=O)(=O)c2c[nH]c(-c3nnc(C)o3)c2)cc1 +O=C(NC1CC1)N1CCCN(C(=O)c2cccc(Cl)c2)CC1 +CC(NC(=O)CCCc1nc2ccccc2[nH]1)c1ccc(F)cc1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)NC(C)C(C)CO)c1 +CC(C)NC(=O)C1CCC(CNC(=O)c2cnc3ccoc3c2)CC1 +Cc1noc(C)c1C(C)NC(=O)c1sccc1OC(F)F +COCCNS(=O)(=O)c1ccc(OC)c(C)c1C +CNC(=O)CN1CCN(C(=O)c2cccc(OC)c2)CC1 +O=C(NCc1ccnc(OC2CCOCC2)c1)c1cccc(Cl)c1 +COc1ccc(F)c(NC(=O)NC2CCCc3ccccc32)c1 +C=CCNC(=O)Cn1nnc(-c2ccc(Br)cc2)n1 +COc1ccc(-c2cc(CN(C)C(=O)C(C)C)no2)c(OC)c1 +CC(=O)Nc1cc(F)c(S(=O)(=O)N2CCCCC2)cc1Cl +CCN(Cc1ccccc1)C(=O)c1nccnc1N +CN1C(=O)c2cc(Cl)ccc2NC12C(=O)Nc1c(Cl)cccc12 +O=C(CCc1ncc(-c2ccccc2Cl)o1)OCc1ccccn1 +CCCS(=O)(=O)N1CC2CC(C(=O)NCC(C)C)C(C1)O2 +Cn1nc(C(=O)Nc2nccs2)cc1NC(=O)c1ccco1 +CCCCCN(C(C)C)S(=O)(=O)c1ccc(O)cc1 +O=C(NCCNc1ncccn1)NCc1ccccn1 +CCN1CCN(S(=O)(=O)c2cccc3nonc23)CC1 +COC(=O)CSc1ncc2c(c1C#N)CCCC2 +CCOC(=O)C1CCN(C(=O)Nc2cccc(Cl)c2F)CC1 +CC(O)c1ccc2ccccc2c1OCCCC#N +COc1ccccc1CCN(C)S(=O)(=O)c1ccc(F)c(C#N)c1 +Cc1cc(NC(=O)CSc2nc(CC(C)C)n[nH]2)no1 +CCOc1ccc(NC(=O)C(CC)CC)cc1OC +O=C(Nc1cc(Cl)ccc1-n1cncn1)C1CC1c1ccccc1 +O=C(NCCc1ccoc1)c1cnc2ccccc2n1 +CCCCCCNC(=O)C(N)c1ccccc1Cl +CCc1nnc(CSc2nnc3n2CCCCC3)o1 +CCCC(=O)NCc1ccc(OCC(F)(F)F)cc1 +COCCNS(=O)(=O)c1ccc(Nc2nc(C)cc(C)n2)cc1 +CCNC(=O)N1CCCN(S(=O)(=O)C(C)C)CC1 +O=C(Nc1cc2c(cc1Cl)OCCO2)NC1CCC(O)CC1 +O=S(=O)(c1ccccc1F)N(CC(F)(F)F)C1CCOCC1 +COc1cc2c(cc1O)C(c1nccs1)NCC2 +CCc1nc(NC(C)CC)c(N)c(OCC(C)C)n1 +CC1CCN(C(=O)c2cc3c(F)cccc3n2C)CC1 +O=C(NCCc1cn2ccccc2n1)Nc1cccnc1 +C=CCn1c(=NC(=O)CN(C)S(C)(=O)=O)sc2ccccc21 +C=CCN1C(=O)c2ccccc2NC1c1cn(C)c(=O)n(C)c1=O +COc1ccc(-c2nc(NCC3CCCO3)sc2C)cc1 +COCC(C)NC(=O)c1cnc2c(cnn2Cc2ccccc2)c1 +COc1ccc(CCC(=O)Nc2ccccc2N)cc1OC +Cc1ccc(N2CCC(n3cc(Cc4ccccc4)nn3)CC2)nn1 +O=C(Nc1ccccc1-n1ccnc1)c1c[nH]c2cccc(F)c12 +O=C(NC(c1ccccc1)c1cccs1)C1CC1 +Cc1ccc(CCNC(=O)c2cccc(-c3ccoc3)c2)cn1 +CCOC(=O)c1c(-c2cccnc2)oc(N)c1-c1ncc[nH]1 +O=C(OCc1nc(-c2cccc(Cl)c2)no1)C1CCCO1 +Cc1cccc(CC(=O)Nc2sc(C)c(C)c2C#N)c1 +CCCn1c(C)cc(-c2csc(NC(=O)C(C)OC)n2)c1C +O=C(Nc1ccc(-c2cc[nH]n2)cc1)c1ccccc1 +CC(Cc1ccc2ccccc2c1)NC(=O)CCNS(C)(=O)=O +O=c1[nH]c2ccc(F)c(F)c2n1Cc1ccc(F)cc1 +O=C1CCC(C2NCCc3c(F)cc(F)cc32)N1 +Cc1ncsc1C(=O)N1CCN(C(=O)N(C)C)CC1 +COCCOC(=O)C(C)N1C(=O)COc2ccc(N)nc21 +O=S(=O)(Oc1ccc2c(c1)OCO2)c1ccc2c(c1)OCCO2 +Cc1noc(C)c1C(C)NC(=O)c1cccnc1SC(F)F +CC(NC(=O)N1CCOC(C(N)=O)C1)c1ccc(Cl)cc1Cl +COC(=O)CC1CCN(C(=O)CCn2ccc3c(C)cccc32)CC1 +Cc1ccsc1C(=O)N1CCN(C(=O)Cc2ccccc2F)CC1 +COC(=O)c1ccc(NC(=O)C(NC(C)=O)C(C)C)cc1 +CCCCc1cc(NC(=O)c2ccc(Cl)cn2)[nH]n1 +O=C1CN(C(=O)C2CCCCC2)c2ccncc2N1 +CN(Cc1cc(-c2ccncc2)no1)C(=O)c1cn2ccsc2n1 +CN1CCN(C(=O)COCC2CCCO2)C(c2ccccc2)C1 +CCc1nc(-c2ccc(C(=O)NCC(C)Cn3cccn3)cc2)n[nH]1 +O=C(Cc1cccc2ccccc12)N1CCN(Cc2ccncc2)CC1 +O=C(CC(F)(F)F)Nc1ccc(F)c(NC(=O)c2ccsc2)c1 +Nc1ncn(-c2ncc(C(F)(F)F)cc2Cl)n1 +Cc1nn(-c2ccccc2)nc1C(=O)N1CCOC2CCCC21 +COC(=O)C1(S(=O)(=O)c2ccc(Cl)cc2)CCCC1 +N#Cc1ccccc1OCC(=O)NCCc1ccccc1F +O=C(Nc1cccc(-n2ccnn2)c1)c1cccc(OCC(F)F)n1 +CCSc1cc(OC)c2c(c1OC)CNCC2(C)C +COCCN1CCN(C(=O)c2cccc3cn[nH]c23)CC1=O +C=CCN1C(=O)COc2ccc(NC(=O)c3cccc(Cl)c3)cc21 +O=C(COc1ccccc1Cl)NCCCN1CCOCC1 +Nc1ncccc1C(=O)OCCOc1ccccc1 +c1cc(-c2cnccn2)cc(-c2ccn(Cc3nnc(C4CC4)o3)n2)c1 +O=C(NCCc1ccccc1)c1cccc2cc[nH]c12 +N#Cc1ccccc1N1CCN(CC(O)c2ccccc2)CC1 +COc1ccc(-n2ccc(C(=O)Nc3ccccc3C#N)n2)cc1 +Cc1nccn1-c1ncc(NC(=O)CNC(=O)c2ccccc2)cn1 +CC(C)CNC(=O)COC(=O)c1ccc(O)cc1 +CCCCNC(=O)C1c2ccccc2C(=O)N(C)C1c1cccs1 +COc1ccccc1CC(C)NCc1ccc(-n2ccnc2C)nc1 +CC(C)(CNC(=O)C1CCCCC1)c1ccncc1 +O=C(NCc1ccncc1)NCc1cccc(NC(=O)C2CC2)c1 +c1ccc(-n2cccn2)c(CN2CCCC(c3nnc4n3CCC4)C2)c1 +Cc1ccc(CNS(=O)(=O)c2ccc(-c3cc(C)no3)o2)cc1 +O=c1[nH]ncc(NCCCc2ccc(Cl)cc2)c1Cl +CCN(CC(F)(F)F)S(=O)(=O)c1cc(N)ccc1F +COCCN1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1=O +O=C(Nc1cccc(-n2cnnn2)c1)c1cnc(C2CCCO2)s1 +O=C(c1ccc2[nH]ccc2c1)N1CC(c2nc(-c3cnccn3)no2)C1 +Cc1cc(C(=O)N2CCN(Cc3ccc4c(c3)OCCO4)CC2)no1 +O=C(NCc1ccccc1)c1nc(-c2ccc(F)cc2)no1 +O=C(NC1CC1)C1CC(=O)N(c2ccc(Br)cc2)C1 +CCOc1cccc2c1CCNC2c1cnccn1 +Cc1cc(C(=O)N(C)Cc2ccc(O)cc2)c2c(C)nn(C)c2n1 +Cn1ncc(C(=O)N(CCO)Cc2ccccc2)c1-n1cccc1 +CNc1nc(-c2cc(Br)cs2)cs1 +COCCC1(CNC(=O)NC2CC(C)C2)CCC1 +CC1CCCC(NC(=O)c2cc(Cl)ccc2-n2cnnn2)C1 +CCC(CC1CCCC1)C(=O)N1CCCC(NC(C)=O)C1 +CC1CN(C(C)(C)CNC(=O)NCCC(=O)N(C)C)CC(C)O1 +CN(C)c1ncccc1C(=O)NCc1nnc2n1CCCCC2 +Cc1noc(C)c1COc1ccccc1C(=O)C(C#N)c1ccccn1 +COCCN(Cc1cnc2ncccn12)C(C)C(N)=O +Cn1nccc1-c1cccc(-c2csc(C(N)=O)c2)c1 +COc1ccc(NC(=O)C(C)n2cc(CO)nn2)cc1Cl +O=C(Nc1ccncc1)c1ccc(-n2ccnc2)nc1 +CC(C)(C)C(=O)N1CCN(C(=O)Nc2ccc(F)c(F)c2F)CC1 +CC(c1cccnc1)N1CCN(c2nccs2)CC1 +NC(CCc1ccccc1)C(=O)NCc1ccco1 +O=C(NCC(c1ccccc1)N1CCOCC1)c1ccsc1 +Cc1nnc(C(C)N2CCN(c3ccc(C#N)cc3F)CC2)o1 +CCOc1cc(C)c(Cl)cc1S(=O)(=O)N(CC)CC +N#CC(C(=O)C1CCOCC1)c1nc2ccccc2[nH]1 +CC(C)N(C)C(=O)C1(S(=O)(=O)c2ccc(Cl)cc2)CCCC1 +CS(=O)(=O)NCc1ccccc1-n1ccnc1 +CN1C(=O)CCC(C(=O)N2CCCC2)C1c1ccccc1 +COc1ccsc1C(=O)NCC1(c2ccccc2)CC1 +CC(C)CC(CNC(=O)N1CCOCC1C1CC1)N1CCOCC1 +Cc1cccc(C)c1N(CC(=O)NCc1ccccn1)S(C)(=O)=O +Cc1ccc2[nH]nc(C(=O)Nc3nc(-c4ccccn4)cs3)c2c1 +Cc1ccc(C(=O)NC2CCN(S(C)(=O)=O)CC2)cc1F +CC(c1cccs1)N(C)CC(=O)c1c[nH]c(C(=O)N2CCCC2)c1 +O=C(NCc1ccncc1)c1scnc1C1CC1 +Cn1nc(Cn2cccn2)c2c1CN(C(=O)c1ccco1)C2 +Cc1cccc(CN(C(=O)c2ccccc2F)C2CC2)c1 +CC(=O)N1CCCCC1C(=O)Nc1ccc(Cl)cc1 +O=C(Nc1ccccc1-n1ccnn1)c1ccc(OCC(F)F)nc1 +COc1cccc(-c2ncnc(N3CCCCC3)c2N)c1 +O=C(c1cnccn1)N1CCOC2CCC1C2OCc1ccncc1 +CC(C)CNC(=O)C1CN(c2ncnc3c2nnn3C)C1 +CC(CCCO)NC(=O)NC1CC1c1c(F)cccc1F +O=C(CNC(=O)NCc1ccco1)Nc1ccccc1 +O=C(NCc1ncc[nH]1)c1cccc(-c2ccoc2)c1 +O=C1COc2cc(C(=O)NCc3ccccc3)ccc2N1 +COC(=O)N1CCC(CNC(=O)CCCc2ccccc2)CC1 +CC(=O)Nc1ccc(C(=O)Nc2cnccc2C)cc1 +CN(CCCNS(=O)(=O)c1ccccc1)c1ccccc1F +CCOCCCNC(=O)c1nnc(-c2oc3ccc(C)cc3c2C)o1 +O=C(NCc1ccc2ccccc2c1)NCC(F)(F)F +Nc1cccc(-c2nnc3c(OCCCO)cccn23)c1 +CC1CN(C(=O)NC(C)c2ccccc2Cl)CCO1 +Cc1cc(Cn2cc(-c3cnn(Cc4cc(C)on4)c3)cn2)no1 +CN1CCN(C2CCN(C(=O)c3ccc(F)c(F)c3)CC2)C1=O +O=C(c1cncc(-c2ccccc2)c1)N1CCCC2(C1)OCCO2 +COc1ccc(-n2nc(C(F)(F)F)cc2CO)cc1 +COc1ccc2nc(CN3CCN(CC(=O)NC(C)C)CC3)[nH]c2c1 +CNS(=O)(=O)c1cc(C(=O)NCC(C)C)cc(C)c1C +CC(=O)N1CCc2cc(NC(C)C(=O)Nc3ccccc3C)ccc21 +Nc1nc(CN2CCc3cc(F)ccc3C2)nc2ccccc12 +COc1cccc(-n2nnc(C(=O)NC3CCCC3)c2C)c1 +Cc1cccc(CC(=O)OCC(=O)Nc2ccccc2)c1 +CCOC(=O)Cn1c(C(CC)CC)nc2c(N)cccc21 +COc1ccccc1NC(=O)C(C)n1nc(C)cc1C +Cc1coc2cc3oc(=O)c(CCC(=O)NC(C)C)c(C)c3cc12 +CC(C)(C)NC(=O)c1ccccc1NC(=O)NCCc1cccnc1 +CC(=O)N1CCOC2CN(C(=O)COc3ccccc3)CCC2C1 +COc1ccc(C(O)CNc2cc(C)ccc2C)cc1N +O=C(NCC(F)(F)F)c1ccc(F)c(F)c1F +COc1cccc(NC(=O)Cc2cc(OC)c(OC)c(OC)c2)c1 +O=C(NCCCCN1CCOCC1)NC1c2ccccc2CC1O +O=C(NCC1(O)CCCc2ccccc21)c1ccc2cc[nH]c2c1 +Cc1c(CCC(=O)N(c2ccc(F)cc2)C2CCCC2)cnn1C +Cc1cc(C(=O)CCC(=O)N(C)CC(=O)N(C)C)c(C)s1 +CCOC(=O)c1cnc(SCc2nc(C)no2)nc1N +c1ccc(CNc2cccc(-c3nccs3)c2)nc1 +COc1ccc(CNC(=O)C2CC(=O)N(C)C2)c(OC)c1 +O=C(COc1ccc(Cl)cc1Cl)NCC(O)c1ccsc1 +NC(=O)c1ccc(CN2C(=O)c3ccccc3S2(=O)=O)cc1 +Cc1cc(NCc2cnc(C3CC3)s2)ccc1F +COc1ccc(N2CCN(CC(=O)N3CCCC3)C2=O)cc1OC +CC(C)c1nnc2n1CC(Nc1ncccc1C#N)CC2 +COc1ccc(C2(O)NC(=O)c3c2c(C#N)c(N)[nH]c3=O)cc1 +Cc1nc(NC(=O)NC(C)CC(N)=O)sc1C +Cc1nnc(CN2CCCc3c(NC(=O)OC(C)(C)C)cccc32)o1 +CCOC(C)c1noc(COc2cccc(CO)c2)n1 +CC(C)(C)C(=O)N1C2CCC1CC(S(=O)(=O)c1ccccc1)C2 +COC(=O)c1cccc(OCC(=O)Nc2ccc(C(C)=O)cc2)c1 +CN(CC(=O)Nc1cc(F)c(F)c(F)c1)C(=O)c1cccs1 +CC(=O)c1nc2ccccc2n1C1CCN(C(=O)OC(C)(C)C)C1 +COc1ccc(-c2nnc(C)o2)cc1NC(=O)N1CCOCC1 +COc1ccc(NC(=O)c2ccc(-c3ccsc3)nc2)cc1 +NC(=O)Nc1ccc(NC(=O)c2cccc(-n3cccn3)n2)cc1 +CCc1nn2c(CNC(=O)c3ccc(F)c(F)c3)c(C)nc2s1 +CCCc1nnsc1C(=O)N1CCN(CC(=O)c2ccco2)CC1 +CCCNC(=O)c1nn(-c2ccc(F)cc2)c2ccccc2c1=O +O=C(CCCn1cccc1)N1CCN(c2ccccc2F)CC1 +CCn1cc(CN(C)C(=O)c2cc(SC)ccc2Cl)cn1 +CC(C)(C)C(=O)N1CCCC(C(=O)NC2COc3ccccc3C2)C1 +Cc1ccc(NS(=O)(=O)N2CCCCCC2)c(O)c1 +Cc1c[nH]nc1C1CN(S(=O)(=O)c2cn(C)cn2)C1 +Cc1cccc(C(=O)Nc2cc(N3CCOCC3)ncn2)c1 +CC(C)NC(=O)Cn1cc(Br)c(=O)[nH]c1=O +COc1cc(C2(C(=O)N3CCC(N(C)C(C)=O)CC3)CC2)ccc1C +Cc1nc2ccc(NC(=O)Cn3cnc4ccccc4c3=O)cc2o1 +CCNC(=O)C(C)n1nc(-c2ccc(OC)cc2)c(OC)cc1=O +O=C(CN1CCCCC1=O)Nc1cccc(C#Cc2ccccc2)c1 +Cc1noc(Cn2nnc(-c3cccc(C(=O)OC(C)C)c3)n2)n1 +NS(=O)(=O)c1cc(C(=O)NC23CC4CC(CC(C4)C2)C3)cs1 +O=C(CNC(=O)NCCCN1CCCCCC1=O)Nc1ccccc1 +Cc1cc(C(=O)Nc2nc(-c3cccs3)cs2)nn1C +CCOc1ccc(C(=O)NC(C(N)=O)C(C)CC)cc1 +CCN(CC(F)(F)F)C(=O)CCc1c(C)noc1C +COC1CCC(CC(=O)Nc2cc(-c3ccccc3)on2)CC1 +CCOC(=O)NCCC(=O)N(C)Cc1ccsc1 +O=C(NCc1nc(C2CC2)cs1)NC(CO)c1ccccc1 +CCc1nnc(NC(=O)N(C)Cc2ccccc2N2CCCC2)s1 +COc1ccc2nc(NC(=O)c3ccc(C(N)=O)cc3)sc2c1 +CC(C)(C)C(=O)N1CCOC(c2ccc(F)cc2)C1 +CCc1cc2c(=O)n(CCC(=O)OC)cnc2s1 +CC(=O)Oc1ccc2c(c1Br)CCCC2 +CCOc1ccc(F)c(C(=O)N2CC(C)OC(CC)C2)c1F +Cc1ccoc1-c1noc(N)c1-c1cccc(F)c1 +Cc1ccc2ncc(C(=O)N3CC(C(N)=O)CCC3C)c(=O)n2c1 +COc1ccc(CN(C(=O)c2ccc3[nH]nnc3c2)C2CC2)cc1 +COc1cccc2c(=O)c(C(=O)NCCc3cccs3)cn(C)c12 +Cc1ccc(S(=O)(=O)NCc2cccnc2)cc1C(N)=O +NC(=O)C(OC(=O)c1ccsc1)c1ccc(F)cc1 +COCCC1CCN(C(=O)CN(C)C(=O)c2ccccc2)CC1 +CCSc1cc(Cl)ccc1C(=O)NCCC(N)=O +Cc1c(Cl)cccc1NC(=O)COc1ccccn1 +COc1ccc(S(=O)(=O)NCc2cc(C)oc2C)c(C)c1 +COc1ccc(CNC(=O)N(C)C(C)C)cc1OC(F)F +CCN(CC)C(=O)c1ccccc1NC(=O)c1ccc(F)cc1 +CCN(CC)c1nc(C)nc2sc3c(c12)CCC3 +Cc1noc(C)c1CC(=O)N(C)Cc1ccc2c(c1)OCO2 +CC(C(=O)N(C)C)S(=O)(=O)c1cccc(Cl)c1 +CC(=O)N1Cc2ccccc2CC1C(=O)N(C)Cc1c(C)noc1C +Cc1nc(NC2CC2)c2c3c(sc2n1)CCCC3 +CCc1noc(CN2CCCc3ccc(S(N)(=O)=O)cc32)n1 +COc1cnc(N2CCCC3(CCC(=O)N(CC4CC4)C3)C2)nc1 +Cc1nn(C)c2sc(C(=O)N3c4ccccc4CC3C)cc12 +COc1ccccc1CCCNc1nccc(-c2ccccn2)n1 +O=C(NCc1ccc(Br)cc1Cl)c1ccncc1 +Cc1nc(NC(=O)CSc2nccn2-c2ccccc2)sc1C +Cc1cccc(C(=O)Nc2ccccc2Br)c1N +CC(C)(C)c1nc(Cn2cc(-c3nnco3)ccc2=O)cs1 +O=C(NC(c1ccc2c(c1)OCCO2)C1CC1)c1ccc(=O)[nH]c1 +NC(=O)C1CN(C(=O)Nc2ccc3c(c2)Cc2ccccc2-3)CCO1 +Cc1ncsc1C(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +COc1ccc2nc(OC3CCN(C(=O)C(C)(C)C)CC3)sc2c1 +Cc1cc(C(=O)Nc2nc(C(N)=O)cs2)c(C)o1 +O=c1c2c(-c3cccs3)csc2ncn1CC1N=CC=N1 +COC(=O)c1cc(S(=O)(=O)Nc2ccc(C)cn2)cn1C +O=C(CCc1nc2ccccc2s1)N1CCC(n2cncn2)CC1 +CC(=O)N1CCN(C(=O)C(O)c2ccc(Cl)cc2)CC1 +COc1cccc(NC(=O)c2n[nH]c3ccc(C)cc23)c1 +O=S(=O)(NC1CCC2CCCC21)N1CCCC1 +Cc1n[nH]cc1CNC(=O)c1ccc(Cl)c(N)c1 +COc1ccc(C(=O)Cn2c(-c3cccnc3)noc2=O)cc1F +CC(C)CC(NS(=O)(=O)C(C)C)c1ccccc1 +CCN(Cc1cc2ccc(C)cc2[nH]c1=O)C(=O)C(C)(C)C +Cn1cc(C(=O)Nc2ccc(F)c(F)c2F)ccc1=O +Cc1cccc(C(=O)Nc2nnc(C3CC3)s2)c1 +CCC(Sc1nc(C(C)C)cc(=O)[nH]1)C(=O)O +CC(C#N)CNC(=O)c1cccc(NC(=O)c2cccnc2)c1 +O=C(CC(O)(c1ccccc1)C(F)(F)F)N1CCC2(CCC2)C1 +COc1ccc(-n2ncc3c(N4CCCC4)ncnc32)cc1 +CC(NC(=O)CC1(C)CCCCC1)C1CCOC1 +CC(C)Oc1cccc(C(=O)Nc2ccccc2C(N)=O)c1 +O=C1NCc2cccc(NCc3nc(-c4cccc(Cl)c4)no3)c21 +CCC(=O)NCC(=O)Nc1ccc(OCc2ccccn2)c(Cl)c1 +Cc1n[nH]c(C)c1CNC(=O)Nc1ccc(C#N)cc1 +COc1c(OC(C)C)ccc2c1C(c1cc[nH]c1)NCC2 +Nc1nc(SCc2ccc(Br)cc2Cl)n[nH]1 +Cc1ncsc1C(=O)N(C)c1ncccc1Br +CCNC(=O)CNC(=O)Nc1ccc(Oc2cccc(F)c2)cc1 +O=C(CN1C(=O)CCS(=O)(=O)c2ccccc21)NC1CCCC1 +NC(=O)c1cnn2c1NC(c1cccs1)CC2C(F)(F)F +CCOC(=O)C1CCN(C(=O)c2cn3nc(OCC)ccc3n2)CC1 +OCCn1c(C2CCCO2)nc2cc(Cl)ccc21 +COc1ccc(-n2cnnc2SCC(=O)Nc2cc(C)on2)cn1 +Cc1n[nH]c(=O)nc1NCc1ccc(S(N)(=O)=O)cc1 +COc1ccccc1C(C)N(C)C(=O)c1ccc(-n2ccnn2)cc1 +COc1ccccc1NC(=O)C1C2CC3OC(=O)C1C3C2 +NC(=O)c1cncc(CCOc2ccc(F)cc2)c1 +Cc1ccnc(NC(=O)c2coc(-c3ccccc3)n2)c1 +COC(CCc1ccc2c(c1)oc(=O)n2C)(OC)OC +CC(C)CN(C(=O)CN1CCOCC1C1CC1)C(C)C +CCCN1CNc2c(c(=O)[nH]c(=O)n2-c2ccccc2)C1 +CCN1CCOc2ccc(NC(=O)C3CCCC3)cc2C1=O +CCOc1ccc(OCC(=O)Nc2ccc3nc(C)sc3c2)cc1 +O=C(C1CC(=O)N(c2ccc3c(c2)OCCO3)C1)N1CCCC1 +CS(=O)(=O)N1CC(C(=O)NCc2ccccn2)Oc2ccccc21 +CCn1cc(NCc2csc3ccccc23)cn1 +COc1cc(C)sc1C(=O)NCCN1CCOCC1 +CCOC(=O)CC1NCCc2ccc(OC)c(F)c21 +CC(C)(C)c1cc(NC(=O)CCC2CCCO2)n(-c2ccccn2)n1 +CC(Nc1ncnc(N2CCCC2)c1N)c1ccccc1 +CCN(CC)C(=O)CCSc1nnc(-c2ccco2)o1 +Cc1nn(C)c(C)c1CNC(=O)Cc1csc(-c2cccs2)n1 +COc1cc(C)c(C(=O)NCc2cccnc2OC)cc1OC +COc1ccc(Cl)cc1NCc1cc2ccc(C)cc2[nH]c1=O +CCCn1c(SCC(=O)NC2CCCC2)nc2ccccc2c1=O +O=C(c1ccccc1-n1ccnn1)N1CCc2[nH]ncc2C1 +CC(C)NC(=O)CN(C)C(=O)c1ccc2c(c1)CCC2 +Cc1cn(C2C=CC(COC(=O)c3ccccc3)O2)c(=O)[nH]c1=O +CCCn1c(-c2cccc(OC)c2)ccc(C(C)(C)O)c1=O +Cc1nc(-c2ccncc2)ncc1C(C)NC(=O)Cc1cccs1 +OC1=Nc2c(ncn2-c2ccc(F)cc2)C(c2cccs2)C1 +Nc1ncc(S(=O)(=O)Cc2cccs2)c(N)n1 +Cc1ccc(N2CCCN(C(=O)c3csc(C)n3)CC2)nn1 +CC(=O)NCC(=O)N(Cc1cccc(Cl)c1)C(C)C +NC(=O)c1ccc(OC(C(N)=O)c2ccccc2)cc1 +COC(=O)C1CCN(C(=O)CCOc2ccc(C)cc2)CC1 +NC(=O)CCCNC(=O)Cc1cccc(C(F)(F)F)c1 +Cc1n[nH]c(C)c1S(=O)(=O)N1CCCc2cc(F)c(F)cc21 +CC(CO)NC(=O)c1ccc(COC(C)C)cc1 +O=C(NCc1cn(-c2ccccc2)nn1)c1cccc(F)c1Cl +Cc1sc(=O)n(CC(=O)Nc2ccc3c(c2)OC(C)(C)O3)c1C +Cc1ccc2ncc(C(=O)NCc3cc4ccccc4[nH]3)n2c1 +CC1Cc2ccccc2N1C(=O)NC1CC(=O)N(c2ccccc2)C1 +Cc1ccc(C(C)NC(=O)c2csc(-c3ncccn3)n2)cc1 +C=CCn1c(N)nnc1SCCOc1ccc(F)cc1 +CC(C)c1ccc(C(NS(N)(=O)=O)c2cccs2)cc1 +CC(OC(=O)C1CCCCC1)C(=O)Nc1cccc(C#N)c1 +COc1cc(C)c(-c2nn3cc(N)nc3s2)cc1C +O=C(NC1CCCCCC1)N1CCN(C(=O)c2ccco2)CC1 +CCCC(=O)Nn1c(C)nc2sccc2c1=O +COc1ccc(-c2nc3sc(CC(C)C)nn3c2C#N)cc1 +COc1ccc(NC(=O)CCc2nc3ccccc3s2)cn1 +CCN(C(=O)c1ccc(N(C)C)cc1)C(C)c1ccc(C#N)cc1 +CN(Cc1nc2ccccc2[nH]1)C(=O)OCC(F)(F)F +NC(=O)C1CN(C(=O)NCc2ccc3c(c2)CCC3)CCO1 +CC(C)CNC(=O)c1nnn(-c2ccc(F)cc2)c1-c1ccncc1 +CCC(NS(=O)(=O)c1cccc(-n2cnnn2)c1)c1cccs1 +CC(C)c1cccc(S(N)(=O)=O)c1OC1CC1 +COc1ccc(-c2nnc(SCCCC#N)o2)cc1 +Cc1cc(Cl)ccc1NC(=O)Cn1ccc2c(=O)[nH]ccc21 +C#CCN(Cc1ccco1)C1CCN(CC(F)(F)F)C1=O +CCNC(=O)C(C)NC(=O)c1ccc(NCC)nn1 +O=c1[nH]c2cc3c(cc2cc1CN1CCOCC1)NCCC3 +Cc1nnc2ccc(-c3noc(-c4ccccc4)n3)cn12 +CCn1c(-c2ccc(OC)c(OC)c2)ccc(C#N)c1=O +CNC(=O)c1ccc(CN(C(=O)c2cc(C)n[nH]2)C2CC2)cc1 +OCCn1c(-c2cccc(F)c2)nc2cccc(F)c21 +Cc1ccc(SCC(F)(F)F)c(NC(=O)N2CCNC(=O)C2)c1 +COc1ccc(CC(=O)N2CCC(C(N)=O)CC2)c(OC)c1 +O=C(Nc1ccc2nn[nH]c2c1)c1cccc2cc[nH]c12 +COc1ccnc(NC(=O)C2(Cc3ccccc3)CC2)c1 +Cc1cc(C)c(CNC(=O)Cc2ccc(C)nc2)c(C)c1 +CC1CCCC1NC(=O)C1CCCCN1C(=O)OC(C)(C)C +Cc1cc(C)n(Cc2ccc(C(=O)OCc3cnn(C)c3)cc2)n1 +COc1ccc2c(c1)CCCN2C(=O)c1ccnc(N(C)C)c1 +CCOc1ccc(C(C#N)NCc2ccccc2OC)cc1 +CC(C)N(C)C(=O)c1coc(COc2ccccc2F)n1 +CCOc1ccc(C(=O)NCCNC(=O)c2ccccn2)cc1Cl +CNc1nnc(-c2ccc(Cl)c(S(N)(=O)=O)c2)s1 +COC(=O)C1CCCN1C(=O)c1cn(C2CCCCC2)nn1 +O=C(Cc1cn2ccccc2n1)N1CCc2cc(F)ccc2C1 +Cc1cnc(NC(=O)CCc2c[nH]c3ccccc23)s1 +O=C(Cc1noc(C2CCCC2)n1)NC1CCCC1 +CC(O)CN1CCN(C(=O)CC2CCCCC2)CC1 +CCCn1nccc1NC(=O)C1CC1c1ccccc1 +CCN(CCC(=O)OC)C(=O)c1cc(-c2csc(C)n2)cn1C +Cc1noc2ncc(C(=O)NC(C)Cn3ccnc3)cc12 +COc1ccc2[nH]c(CNc3nc(C)cc(C)n3)cc2c1 +CN1CCN(C2CCN(c3nccc(C(F)(F)F)n3)CC2)C1=O +COc1cc(F)c(S(=O)(=O)NCC2CCC2)cc1OC +N#Cc1cc(N)ccc1NC(=O)c1cncc(Br)c1 +Cc1nc(CNc2cc(C)c3ccc(Cl)cc3n2)cc(=O)[nH]1 +CC(C)OCCCC(=O)Nc1ccc(Cl)c(N)c1 +COc1ccccc1C(CNC(=O)c1cc(C)oc1C)OC +CCOc1ccc(CC(=O)N2CCNC(=O)C2c2ccccc2)cc1 +O=C(CCNC(=O)c1ccsc1)Oc1ccc2cn[nH]c2c1 +CCC(C)NC(=O)CC1Sc2ncccc2N(C)C1=O +CN(C)c1ccc(C(=O)Nc2ccccc2C(=O)NC2CC2)cc1 +CC(C)N(C(=O)CCc1nc(-c2ccsc2)no1)C1CCOCC1 +Cc1cccc(-n2nnnc2SCC(=O)c2ccccc2F)c1 +CS(=O)(=O)c1ccc(OCc2csc(-c3ccccn3)n2)cc1 +O=C(C1CCCO1)N1CCOC2C(COc3ncccn3)CCC21 +Cc1cnc(NC(=O)c2c(C)nc3ccccn23)s1 +NC(=O)c1cccc(CSc2nccn2-c2cccc(F)c2)c1 +CN1C(=O)CCc2cc(-c3cc(=O)[nH]c(N)n3)ccc21 +CCOC(CC)C(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1 +CN(C)C(=O)Cc1ccc(NCc2cccc3cccnc23)cc1 +O=C(NCc1nnc2ccccn12)c1cc2ccccc2s1 +O=C(CCCOc1cccc(F)c1)Nc1nncs1 +CCC(C)Sc1nnc(-c2ccoc2C)n1C +Cc1ccnc(NC(=O)C2CCCCN2C(=O)c2cccs2)c1 +Cc1cc(NC(=O)NCc2cnn(C)c2C)ccc1F +CCC(=O)Nc1ccc(O)c(C(=O)Nc2cccc(C)n2)c1 +Cc1c(C(=O)Nc2ccc(C(F)(F)F)cc2)cnn1-c1ccccn1 +CC(=O)Nc1ccsc1C(=O)N(Cc1cnn(C)c1)C1CC1 +Cc1ccc(NS(=O)(=O)c2cccc(S(N)(=O)=O)c2)cc1F +Cc1cc(=O)cc(C(=O)N2CCC(Cc3ccc(CO)cc3)C2)o1 +Cc1ccc(CN(C)C(=O)COC(=O)c2ccc3c(c2)OCO3)o1 +Cc1ccc(NC(=O)Cn2nc(-c3cccs3)ccc2=O)cc1 +COc1ccc(C(=O)N2CCCC(C(N)=O)C2)cc1-c1ccccc1 +CCc1nn2c(=O)cc(COc3ccc(C)cc3)nc2s1 +COC(=O)c1sccc1NC(=O)c1nn(C)c(=O)c2ccccc12 +CCc1c(C)ncn2c(-c3cc(N)ccc3OC)nnc12 +Cc1cc(C(=O)Nc2ccc(Br)cc2)on1 +CCS(=O)(=O)NCC(O)c1ccc2c(c1)CCO2 +CCC(CC)C(O)CNC(=O)C1(O)Cc2ccccc2C1 +O=C(Cc1cc(F)ccc1Br)c1ccccn1 +O=C(NCc1cccc(Oc2ccccn2)c1)c1ccncc1 +CCOc1ccc(N2CCN(CC(=O)N(C(C)C)C(C)C)C2=O)cc1 +COc1ccc(CC(=O)Nc2cc(F)ccc2OC)cc1 +O=C(Oc1ccc2cn[nH]c2c1)c1ccc(-n2cccn2)cc1 +CC(=O)N1CCN(C(=O)C(O)c2ccc(F)cc2)CC1 +CCN(C(=O)Cn1nc(-n2cncn2)ccc1=O)c1ccccc1 +CCc1nc(CC(=O)Nc2cc(C)nn2C)cs1 +C=CCn1c(C2CC2)nnc1S(=O)(=O)CC(=O)NC(C)C +CC(C)(C)NC(=O)N(CCO)Cc1cc(Br)ccc1F +COc1cc(F)cc(CNC(=O)NCc2nc(C)no2)c1 +Cc1cc(NS(=O)(=O)c2ccc3oc(=O)n(C)c3c2)no1 +CC(=O)N1CCC2(CC1)Nc1ccccc1N(CCC#N)C2=O +CCCn1ccc(NC(=O)c2ccncc2)c1C(=O)OCC +Cc1ccc(C(C)NC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +CCCCCn1c(CN(C)C(=O)c2ccncc2)nc2ccccc21 +COc1ccc(OC)c(NCC(O)c2ccc(C)cc2)c1 +CN(CC(O)C(F)(F)F)C(=O)c1cc(F)cc2[nH]cnc12 +COc1cccc(C(O)CCC(=O)NCc2ccccc2)c1 +CCNC(=O)c1cccc(CNC(=O)NCC(O)c2ccco2)c1 +O=C(CSc1nncn1-c1ccccc1)c1cccs1 +CC(C)CNC(=O)C(C)CS(=O)(=O)N1CCNCC1 +CC(=O)Nc1cccc(NC(=O)c2cccc(-c3ccoc3)c2)c1 +Cc1ccc(CN(C)Cc2nc3cc(Cl)ccc3c(=O)[nH]2)cc1 +Nc1cc2c(cc1Cl)[nH]c(=O)c1cc(Cl)ccc12 +COc1ccc(C=Cc2nc3ccccc3[nH]c2=O)cc1 +CN(Cc1nccs1)C(=O)CCC(=O)c1ccc(F)c(F)c1 +O=C(CCCc1ccccc1)NCCc1cn2ccccc2n1 +O=c1[nH]c(=O)n(Cc2ccccc2)c2ncc(CCCO)cc12 +CCCN(CC(F)(F)F)C(=O)c1cccnc1N +C#CCNc1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1 +CCOC(=O)Nc1nnc(SCc2nc3ncccc3[nH]2)s1 +CC(C)OCCCNC(=O)Cc1ccccc1F +CN(CCc1ccccn1)C(=O)CNC(=O)NCC1CC1 +Cc1cc(C)n(CC(C)NC(=O)CCC(=O)c2cccs2)n1 +CC(C)OCCCNC(=O)c1ccc(Cl)c(N)c1 +CC1CCN(S(=O)(=O)NCc2cccc(O)c2)CC1 +CC(C)c1ccc(S(=O)(=O)C(C)C(N)=O)cc1 +Cc1ncc(CNc2ccccc2SCC(F)(F)F)s1 +CCCOc1ccc(C(=O)NC2CCCCNC2=O)cc1OCC +CC1CN(Cc2cccc(C(F)(F)F)c2)C(C)CO1 +O=C(NC1CCCC1)NC1CCN(c2ncccn2)CC1 +Cc1c(Cl)cccc1-n1ccnc1SC(C)C(=O)NC1CC1 +Cc1nn(-c2ccc(Cl)cc2)nc1C(=O)NC1CCCCC1 +Cc1cnc(C(C)NCc2noc(C(C)C)n2)s1 +COCCN(Cc1ccccn1)C(=O)Cc1c[nH]c2cc(F)ccc12 +Cc1ccc(Cl)cc1NC(=O)COc1c(C)occc1=O +O=C(Nc1cc(-c2cccnc2)n[nH]1)c1cccc(-c2ccoc2)c1 +Cc1oc(-c2ccccc2)nc1CC(=O)OCC(N)=O +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NCC1(c2ccccc2)CCC1 +CC(O)c1ccc(S(=O)(=O)N(C)C2CCCC2)cc1 +c1cncc(CNc2ncnc3sc4c(c23)CCCC4)c1 +Cc1ccc(NC(=O)c2cc(Cl)ccc2-n2cnnn2)c(Cl)c1 +COc1cc(OC)c(OC)cc1CNC(=O)c1cnn2ccccc12 +CCOc1ccc(NC(=O)c2cccc(F)c2)cc1 +COc1ccc(NC(C)=O)cc1NC(=O)c1cccc(C#N)c1 +COc1ccccc1CNC(=O)COc1ccccc1N +NC(=O)C1CCN(C(=O)NCCOc2ccc3c(c2)OCO3)C1 +CC=CCOC(=O)CC(NC(C)=O)c1ccc(C)cc1 +CC(C)c1cc(C(=O)N2CCN(C)C(c3ccccc3)C2)[nH]n1 +NC(=O)c1ccc(CNc2cccc3ccccc23)cc1 +CCCC(=O)N1CCCC(COc2ccc(C(=O)NC3CC3)cc2)C1 +CC(NC(=O)c1cccc(F)c1)C(=O)N1CCOCC1 +CCCn1c(SCC(=O)NC2CCCC2)nnc1C(C)C +N#CCSc1cccc(C(=O)NCc2cn(-c3ccccc3)nn2)c1 +CN(CC(F)(F)F)C(=O)CNC(=O)NCc1ccc(F)cc1 +Cc1ccc(N)cc1NC(=O)Cc1ccccc1F +COCCCNC(=O)c1cc(Br)ccc1-n1cccc1 +COCCNC(=O)CN1C(=O)COc2cc(N)ccc21 +COC(=O)C(C)S(=O)(=O)Nc1ccc(N)c(C)c1 +O=C(NCC(=O)N1CCC1)c1cccc(Br)c1 +CNC(=O)c1cnc(C=Cc2cnc(C(C)(C)C)s2)s1 +COc1ccccc1C(=O)Nc1ccccc1-n1cnnn1 +COC(=O)CSc1ccc(NC(=O)c2ccco2)nn1 +O=S(=O)(c1cccc(F)c1)N1CCOC(c2ccc(F)cc2)C1 +Cn1cnnc1Sc1ccc(NC(=O)CCc2ccco2)cc1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)c1ccc2c(c1)OCC(=O)N2 +COc1cc(C(=O)NC2c3ccccc3CC2O)cc(OC)c1C +Cc1cc(C)n(Cc2ccc(C(=O)NCCCC(N)=O)cc2)n1 +COCCCNc1ncnc2c1nc1n2CCCC1 +CCC(C)C(=O)N1CCC(C(=O)NCCCN2CCOCC2)CC1 +CCCC(=O)N1CCc2nc(C3CCCN3C(=O)CC)[nH]c(=O)c2C1 +Cc1ccc(OCCNS(=O)(=O)c2ccc(F)c(F)c2F)cc1 +CCN(Cc1nc(COC)no1)C(=O)c1cc(C)[nH]c(=O)c1 +O=C(Cn1ccccc1=O)c1sccc1Br +Cc1ccc(CCNC(=O)Nc2ccc(Oc3cccnc3)nc2)cn1 +Cc1cn(CC(=O)N2CCN(Cc3csc(C)n3)CC2)nn1 +CNC(=O)c1sc2nc(C(F)(F)F)nn2c1C +CCC(C)NC(=O)c1nc(Cn2c(=O)oc3ccc(C)cc32)no1 +COC(=O)CCCN1C(=O)CNc2cc(Cl)ccc21 +Cc1noc(CCC(=O)N2CCCC2c2ccccc2Cl)n1 +CCC(=O)Nc1cc(S(=O)(=O)NCC2CCCO2)ccc1OC +NC(=O)C1CCN(C(=O)CCc2cccc(Cl)c2)c2ccccc21 +CCc1nc(NCCOC)c2oc3ccccc3c2n1 +Cc1nn(C)cc1C(=O)OCCc1c[nH]nc1C(F)(F)F +Cc1nc(SCC(=O)N2CCC(C)CC2)c2ccccc2n1 +Cc1ccc(NC(=O)CN2CCN(C(=O)c3ccncc3)CC2)cc1 +Cn1nnnc1-c1cccc(NCC(=O)Nc2ccc(Cl)cn2)c1 +O=C(Nc1ccc(Oc2cccnc2)nc1)C1CC1 +COCc1nc2cc(NC(=O)C(C)Sc3ccccn3)ccc2o1 +Cn1c(=O)c2c(ncn2CC(=O)NC2CCCCNC2=O)n(C)c1=O +O=C(Cn1nnc(-c2ccccc2)n1)NCCOc1cccnc1 +Cc1cc(NC(=O)c2ccc3c(c2)NC(=O)CO3)ccn1 +CC1CN(CC(=O)c2ccc(F)cc2)c2c(N)cccc2O1 +O=C(Nc1nnc(C2CCCC2)s1)c1ccc(F)cc1 +CCC(C)C(=O)NCc1cccc(COC(C)C)c1 +CC(C)(C)OC(=O)NCCn1nc2ccccn2c1=O +Cc1[nH]ncc1CCCNC(=O)NC1CCC2(CC1)OCCO2 +CC1=NC(c2cccc(NC(=O)c3cccs3)c2)=NC(=O)C1 +C#CCN1CCN(CC(=O)NCc2cc(F)cc(F)c2)CC1 +O=C(CN1CCOCC1C1CC1)Nc1ccc2c(c1)OCCCO2 +CC(=O)c1ccc(NC(=O)NC2(C)CCOCC2)cc1 +Cn1cnc(CNC(=O)c2cccnc2N2CCCC2)n1 +CCc1ccccc1NC(=O)c1ccc(C#N)cc1 +CC(C)c1nccc(CN2CCCC3(CNC(=O)O3)C2)n1 +O=C(CO)NCc1cc2n(n1)CCCN(C(=O)C1CCC1)C2 +O=C(NC1CCCCNC1=O)c1sccc1-c1ccc(F)cc1 +N#CC1(NC(=O)Cc2cccc(C(F)(F)F)c2)CCOCC1 +CC(C)(C)NC(=O)c1ccc(NC(=O)c2cccnc2)cc1 +CNC(=O)NC1CCCN(c2ccccc2Cl)C1 +CCc1noc(-c2c(C)cc(C)n2CC(=O)Nc2cccc(F)c2)n1 +Cc1nccn1-c1ncccc1NCc1coc(-c2ccccc2)n1 +O=c1cc(Cn2cncn2)nc2n1CCCN(Cc1ccoc1)C2 +Cc1nn(C)c(C)c1CN(C(=O)c1ccc(C)n(C)c1=O)C1CC1 +c1csc(CCNCc2c[nH]nc2-c2cccs2)c1 +CCCCN(CC)C(=O)c1cnc(C2CCCO2)nc1N +O=C1NCCN(C(=O)c2ccc(Cl)cc2)C1c1ccccc1 +O=C(NC1CCN(c2ncccn2)CC1)c1cc2c(s1)CCCC2 +CC(=O)N(C)c1ccc(NC2=NS(=O)(=O)c3ccccc32)cc1 +COc1c(O)ccc2c1C(c1ccc(=O)[nH]c1)NCC2 +COCCNC(=O)N1CCCC1c1cccc(Br)c1 +CC1CCc2c(C(=O)OCC(=O)NCc3ccco3)csc2C1 +CCCn1c(C)nnc1SCC(=O)N(CC)C1CCCCC1 +C#CCNC(=O)NCc1cn2cc(Cl)ccc2n1 +CCS(=O)(=O)c1ccccc1NCc1ccc(C)s1 +COc1ccc(F)c(NC(=O)N(CCO)C(C)C)c1 +CCOc1ccc(C(=O)N=c2sccn2C)cc1OC +COC(=O)Cn1c(CC#N)nc2cc(OC)c(OC)cc21 +CCCCCNC(=O)CN1CCN(c2ccccc2F)C1=O +Cc1ccccc1SCC(=O)NCc1nc2ccccc2[nH]1 +CC(NC(=O)c1cccnc1Oc1ccccc1)c1ccncc1 +O=C(CN1CCOCC1)NCc1cc(Br)cs1 +CCOC(=O)c1nc2ccccc2n(C(C)=O)c1=O +CC(C)c1ccccc1NC(=O)c1ccc2c(c1)OCCO2 +Cc1noc(C(C)OC(=O)Cc2ccc(Cl)cc2Cl)n1 +COCC(NC(=O)c1cc(C)nc2onc(C)c12)C(N)=O +Cc1nc(Cc2cc(F)cc(F)c2)[nH]c(=O)c1C +CC(=O)c1cccc(NC(=O)C(C)(C)c2ccc(N)cc2)c1 +O=C(Nc1ccc(SC2CCCC2)cc1)c1ccncc1 +NC(=O)NCc1ccc(NC(=O)c2ccc3ccccc3n2)cc1 +COc1ccc(-c2cc(=O)[nH]c(C(C)(C)C)n2)cc1N +O=C(Cc1noc(C(=O)NC2CC2)n1)Nc1ccc(F)cc1F +O=C(CNC(=O)c1ccccc1)Nc1ccc(Cl)cc1 +CCn1cc(Cl)c(C(=O)Nc2ccncc2)n1 +COC(=O)CCSc1ncnc2c1oc1ccccc12 +O=C(CCC1(Cc2ccc(Cl)cc2)CCC(=O)N1)NCC1CC1 +CC(=O)N(CCC(=O)N1CCC(CC(N)=O)CC1)Cc1ccccc1 +CCn1ncc(NC(=O)C2CCCO2)c1C(N)=O +CSc1ccc(Cl)c(C(=O)NCCC(=O)Nc2ccncc2)c1 +Cc1nccnc1N1CCC(Cn2cc(CC(C)O)nn2)CC1 +O=C1Nc2ccc(F)cc2C1(O)c1cc(Br)ccc1O +CCOC(=O)c1sc(NC(=O)c2ccco2)c(C(=O)OC)c1C +Cc1ccc(C(=O)NC2CNc3ccccc3C2)cc1C +CC(CC(=O)Nc1ccc(Cl)cc1Cl)C(N)=O +CC(=O)Nc1nc2c(s1)CN(CC(=O)Nc1cccc(C)c1)CC2 +N#CCCN(Cc1cccnc1)C(=O)c1cc(F)c(F)c(F)c1F +Cc1ncc(Cl)c(C(=O)NC(C)C(=O)N2CCOCC2)n1 +COC(=O)C(CNC(=O)C#Cc1ccccc1)Oc1ccc(F)cc1 +CN1C(=O)CCc2cc(-c3nc(-c4ccc(C#N)cn4)no3)ccc21 +CC(=O)c1ccc(OC(=O)c2sc(C)nc2C)cc1 +COc1ccc(CC(=O)N2CCCC2c2cccs2)cc1OC +O=C(Cc1cccs1)N1CCc2cc(F)ccc2C1 +Cc1nnc2c(NC3CC(=O)N(c4ccccc4Cl)C3)nccn12 +Cc1ccc(NC(=O)c2nc3cc(O)ccc3n2C)cc1C +O=C(NCCNC(=O)c1ccc(F)nc1)c1ccc(F)cc1 +COCCOC1CCN(C(=O)c2cnoc2C)C1Cc1cnn(C)c1 +CC(c1cccc(Cl)c1)N(C)C(=O)C1CC(=O)N(C)C1 +CCc1nc2sc3c(c2c2nnc(C)n12)CC(C)(C)OC3 +CCCn1cc(CNCc2cc(=O)c3cc(F)ccc3[nH]2)cn1 +CC(C)c1nc(C2CCCN(C(=O)c3ccc4nncn4c3)C2)no1 +COc1ccc(NC(=O)N(CCO)Cc2ccccc2)cn1 +COc1cc(C)ccc1OCc1nc(C(=O)N2CCOCC2)cs1 +CCc1nnc(SCC(=O)Nc2ccccc2Cl)n1CC +C=CCn1c(SCC(=O)OC)nc2sc(C)c(C)c2c1=O +O=C(Cn1c(=O)oc2ccccc21)N1CCCC1C1CCCCC1 +CNC(=O)c1ccsc1NC(=O)Cc1ccc(OC)c(C)c1 +CS(=O)(=O)N1CCOCC2(CCN(C(=O)c3ccno3)CC2)C1 +O=C(Nc1ccc(N2CCCCC2)nc1)C1CCC1 +CS(=O)c1ccc(CN2CCC3(C2)OCCO3)cc1 +CC(Oc1ccc2c(c1)OCO2)C(=O)Nc1cccc(N)c1 +Cc1ccc(CN(C)C(=O)COc2ccc(C#N)cc2)o1 +O=C(Cn1nc(-c2ccc(F)cc2)ccc1=O)N1CCOCC1 +Cc1ccccc1NC(=O)CNc1ccc(C)c(-n2cnnn2)c1 +COC(=O)c1ccccc1NC(=O)C1CCN(C(=O)C(C)C)CC1 +Cc1cccc(C2(C(=O)NCc3nc(C)sc3C)CCCC2)c1 +CCCN(C)C(=O)c1ccccc1SCC(N)=O +COCCNC(=O)c1cc2sccc2n1Cc1ccc(OC)cc1 +COCCOc1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +Cc1cnn(-c2ccc(C(=O)N3CCOc4ccc(F)cc43)cc2)c1 +CCN(CCc1nccs1)C(=O)C1OCCC1C +O=C(CCc1ccccc1)NC(C(=O)Nc1cc[nH]n1)c1ccccc1 +O=C(Cc1ccc(O)cc1)Nc1ccccc1N1CCOCC1 +Cc1noc(C)c1S(=O)(=O)N(C)C1CCCCCC1 +Cc1ccc(NC(=O)NCc2cc(C3CC3)n(C)n2)cc1C +C=CCN(Cc1ccccc1)C(=O)Nc1ccc(NC(=O)OC)cc1 +NC(=O)C1CCN(C(=O)c2c[nH]nc2-c2ccc(Cl)cc2)CC1 +O=C(CCC(O)c1ccc2c(c1)CCC2)NC1CC1 +CCCCN(CC(N)=O)C(=O)c1ccc(C(C)C)cc1 +Cc1ncc(CNC(=O)Nc2cc(Cl)ccc2C)s1 +O=C(CNC(=O)OCC(F)(F)F)Nc1ccc2ccccc2c1 +O=C(Cn1c(-c2ncccn2)noc1=O)NCc1ccco1 +CC1CN(C(C)C(=O)N2CCc3c(nc(N)[nH]c3=O)C2)CC(C)O1 +CCOc1cc(CNC(=O)NCc2cc[nH]n2)ccn1 +Cc1[nH]c2ccccc2c1C(=O)N1CCN(c2nccs2)CC1 +CCOc1c(OC)cccc1-c1ncc(C(=O)NC)c(N)n1 +CCNC(=O)CN(C)C(=O)c1ccc(OC)cc1O +Cc1ccc2oc(C(=O)Nc3ccc(N(C)C)nc3)cc2c1 +CNS(=O)(=O)c1ccc(Sc2nnnn2C)c(N)c1 +Cc1c(C(=O)NC(C)(C)C)cnn1-c1ccccn1 +O=C(CCC(=O)c1ccccc1)NCC(=O)Nc1cccc(F)c1 +COc1cccc(-c2cc(C(=O)NCC#Cc3ccccc3F)[nH]n2)c1 +Cc1n[nH]c(C)c1CCNC(=O)c1cn(CCc2ccccc2)nn1 +CCn1c2ccccc2n2c(=O)c(Cl)c(C)c(C#N)c12 +CC(=O)N1CCC(C(=O)NC(c2nc3ccccc3[nH]2)C(C)C)CC1 +CCN(Cc1cccs1)C(=O)CNC(=O)c1ccccc1 +O=C(c1c[nH]nc1-c1ccccc1)N1CCN(c2cnccn2)CC1 +COc1ccc(S(=O)(=O)Nc2ccc3[nH]ncc3c2)cc1C(N)=O +O=C(CC1CC2CCC1C2)Oc1cccc(N2CCCC2=O)c1 +CCc1cccc(NC(=O)Cn2ncc(-c3ccccc3)nc2=O)c1 +Cc1ccn(CC(=O)NC2CCCc3nc(-c4ccccn4)ncc32)n1 +CC(C)n1nccc1NC(=O)Cc1ccc(F)c(F)c1 +CC(=O)Nc1cc(C(=O)N2CCOCC2)nn1-c1ccccc1 +CCNC(=O)c1cccc(CNC(=O)CCC(C)C)c1 +CC(NC(=O)c1cn2ccsc2n1)c1nc2ccccc2[nH]1 +CCCCN1C(=O)C(c2ccccc2)Oc2cc(N)ccc21 +O=C(c1c[nH]nc1-c1ccccc1)N1CCN(c2ccccc2)CC1 +COC(=O)c1cc(N)n(-c2ccc(OC)c(Cl)c2)n1 +Cc1noc(CCC(=O)Nc2cccc3c2CCCC3)n1 +CC(C)CNC(=O)CCSc1ccccc1Cl +CC(=O)Nc1ccc(CNC(=O)c2c(C)[nH]c3ccccc23)cc1 +Cc1cccc(NC(=O)CN2CCN(c3ccc(O)cc3)CC2)c1 +Cc1cc(NCc2cc3n(n2)CCCN(C(=O)N(C)C)C3)ncn1 +CCSc1nc2c(c(=O)n1-c1ccc(C)cc1)SCC2 +CCN(CC)c1ccc(C(=O)N(C)Cc2ccccn2)cc1 +O=S(=O)(N1CCOCC1)N1CCC(c2cc(CCO)[nH]n2)C1 +Cc1cccnc1NC(=O)NCc1cc(Br)cs1 +Cc1csc(Cn2cc(C(N)=O)c(-c3ccccc3)n2)n1 +CC(CC(N)=O)C(=O)Nc1ccc(Br)cc1 +CC(C)(C)C(=O)N1CCN(CCNC(=O)c2ccsc2)CC1 +Cc1oncc1C(=O)N1CCC2(CC1)Cc1ccccc1CNC2=O +Cc1n[nH]c(C2CCCN2S(=O)(=O)c2ccc(C#N)cc2)n1 +CC1CCC(NC(=O)C(C)Oc2ccc(S(C)(=O)=O)cc2)CC1 +CS(=O)(=O)N1CCC(Cc2cnc(Nc3cnccn3)cn2)CC1 +CCC(C)C(NC(=O)c1ccc(Cl)cc1)C(=O)NCC(N)=O +CN(C(=O)CCc1cccnc1)C1CCc2ccccc21 +COc1ccc(CC(=O)C(C#N)c2nc3ccccc3[nH]2)cc1 +CN(C)C(=O)c1cccc(OC2CC2)c1C(=O)N(C)C +O=C(NC1CCSc2ccc(F)cc21)c1ccsc1 +N#Cc1cnc(NC(=O)COc2ccc(F)cc2)s1 +COC(=O)Nc1cccc(NC(=O)NC(C)c2c(C)nn(C)c2C)c1 +CCS(=O)(=O)c1ccc(-c2cc(N)nc3[nH]ccc23)s1 +N#CC(Cc1cccc(Br)c1)C(=O)N1CCCC1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)c1ccsc1 +CCCN(C)S(=O)(=O)c1cccc(C(=O)Nc2cc(C)on2)c1 +CCc1nc(CNC(=O)Nc2nc3ccsc3s2)cs1 +Cc1n[nH]c(C)c1CC(=O)NCCOc1cccc2ccccc12 +O=C(CSc1ccc2c(c1)OCCO2)N1CCc2ccccc21 +Cc1ccc(CN2CCCN(Cc3ccccc3F)S2(=O)=O)cc1 +O=C(c1cccc(-n2cccn2)n1)N1CCOCC1C1CC1 +CC(C)Oc1ccccc1NC(=O)c1ccc(S(N)(=O)=O)o1 +O=C(NCc1ccccc1OC(F)F)c1ccc(-n2ccnn2)cc1 +COc1cccc(S(=O)(=O)CCN2CCN(C(C)=O)CC2)c1 +CCCC(NC(=O)NCc1ccc(F)cc1)C(=O)Nc1cccnc1 +Cn1nccc1CCNC(=O)Nc1cc(F)ccc1N1CCCCC1 +Cc1cc(C(=O)N(C)CCCOc2c(C)cccc2C)c(=O)[nH]c1C +COc1cc2c(c3c1OCO3)CN(Cc1ccccc1Cl)CC2O +CC(NC(N)=O)C(=O)Nc1ccc(N2CCCCC2)c2ccncc12 +Cc1cc(C)n(-c2ccc(C(=O)N3CCCC(O)C3)cc2)n1 +COCCCn1c(-c2ccc(C)cc2C)ccc(CO)c1=O +C#CCOc1ccc(CCNS(=O)(=O)c2ccc(C)s2)cc1 +Nc1ccccc1OCCc1nnc(N2CCCCC2)o1 +Nc1ccc(Cl)c(NC(=O)c2ccccc2O)c1 +Cc1ccc(NC(=O)c2ccc(OC(C)C)cc2)cc1N +O=C(NCC(O)COC1CCCCC1)Nc1ccc2ncccc2c1 +CCC(=O)N1CCC(Oc2nncc3ccccc23)CC1 +OC(CN1CCn2c(nnc2C2CC2)C1)c1ccc(F)cc1F +Cc1ccccc1Cn1nc(-n2cncn2)ccc1=O +COC(=O)C(NCC1CC1)c1cc(F)ccc1F +CSc1cncc(NCc2cccc(Cn3ccnc3C)c2)n1 +CC(=O)Nc1ccc(F)c(NC(=O)NCc2nnc3ccccn23)c1 +Cc1cc(C)n(-c2nc(C)c(C)c(=O)n2CC(=O)N2CCCC2)n1 +CNC(=O)CSc1nnc(Nc2ccc(C)c(C)c2)s1 +O=C(COCC1CCCO1)NC1CCN(c2ccc(F)cc2F)C1 +CC(=O)N(CCc1ccccc1)Cc1cc2cc(C)cc(C)c2[nH]c1=O +CCN(CC)C(=O)Cn1c(-c2ccco2)nc2ccccc21 +CC1CCC2(CC1)OCC(CNc1ncnc3nccnc13)O2 +Cc1ccc(N2CC(C(=O)Nc3ccnc(C)c3)CC2=O)c(F)c1 +CN(CCn1cccn1)C(=O)CCc1ncc(-c2ccccc2)o1 +O=C(Cc1ccn[nH]1)NC(c1cccc(Cl)c1)c1ccccn1 +CC(C)(C#N)c1ccc(NC(=O)NC(C(N)=O)C(C)(C)C)cc1 +Cc1cc(C)n(CCCNC(=O)CSc2ccc(F)c(F)c2)n1 +O=C1CCN(c2nc3cc(Cl)ccc3o2)CC1 +COc1ccccc1OCC#CCNC(=O)C1CCC(=O)N1 +Cc1cc(NC(=O)N(C)C(C)c2ccccn2)c2ncccc2c1 +Cc1nc(C(C)C)sc1C(=O)NCCCN1CCCCCC1=O +CCOc1ccc(CC(=O)NCc2n[nH]c(=O)c3ccccc23)cc1 +CC(C)NC(=O)CNC(=O)C(Cc1ccc(O)cc1)c1ccccc1 +CC(=O)Oc1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1 +NC(C(=O)NCCCCCO)c1ccc(O)cc1 +O=C(NCCOCC(F)(F)F)Nc1ccc(Cl)cc1 +Cc1cc(NC(=O)c2ccc(COc3ccccc3Cl)o2)no1 +CCc1nnc(SCC(=O)N2CCN(C)CC2)n1N +O=C(NC1CCCc2ccccc21)c1ccc2c(c1)nc1n2CCOC1 +CCOC(=O)c1cc2c(=O)n(-c3ccccc3)ccc2nc1C +COCC(C)NC(=O)N1CCc2cc(OC)c(OC)cc2C1 +CC(O)c1nc2cc(N3Cc4ncccc4C3=O)ccc2n1C +CCN(Cc1cccc(Cl)c1)C(=O)NCC(C)N1CCOCC1 +Cc1cc(C)cc(OCCCN2C(=O)CCS2(=O)=O)c1 +CCC(C)NC(=O)CN1CCN(C(=O)Cn2cnnn2)CC1 +CCCCC(=O)Nc1cccc(C(=O)N(C)Cc2ccncn2)c1 +NC(=O)c1cc(NC(=O)NCC2(c3ccccc3F)CC2)ccc1F +COc1ccccc1C(=O)C(C#N)c1nc(C)cs1 +CCCN1C(=O)C(Cc2ccc(OC)c(N)c2)Oc2ccccc21 +Cc1ccc(CN(C)C(=O)COc2cccnc2C)o1 +Cc1nn(C)c(C)c1CC(C)NC(=O)Cc1ccc(F)cc1F +Cn1ccc2ccc(NC(=O)Cn3cnc4c(cnn4C)c3=O)cc21 +COc1ccc(CCc2nn3c(-c4ccncc4)nnc3s2)cc1 +CN(C(=O)c1coc(=O)c2ccccc12)c1ccccc1F +Cc1ccc(CNC(=O)CNC(=O)c2cccs2)cc1 +O=C(COC(c1ccccc1)c1ccccc1)NCc1ccco1 +CCCc1cc(=O)[nH]c(SCC2CCCO2)n1 +COC(=O)c1ccc(S(=O)(=O)N(C)Cc2cnn(C)c2)cc1 +CCn1cnnc1-c1cccc(NC(=O)C2CCCCC2)c1 +Cc1ccc(CNC(=O)NCc2ccc3c(c2)OCO3)n1C +Cc1nc(C)c(CNC(C)c2ccc(F)c(Cl)c2)s1 +CCn1c(C2CC(=O)N(c3cccc(OC)c3)C2)nc2ccccc21 +CC(=O)Nc1cccc(Cl)c1Oc1cccnc1 +Cc1cc(N2CCC(NC(=O)C3C4CCCC43)CC2)ncn1 +CN1CC(NC(=O)c2ccc(Cl)c(Cl)c2)CCC1=O +Cc1nnc(-c2ccc(C(=O)Nc3n[nH]c(-c4ccoc4)n3)cc2)o1 +CCCOc1cccc(C2C(C(N)=O)C(C)=Nc3ncnn32)c1 +COc1nn(C)c2c1CCCN(C(=O)Nc1cccc(F)c1)C2 +Cc1ncc(CNc2ccc(N)c3cccnc23)s1 +COc1cc(C(=O)N=c2[nH]nc3cc(C)ccn23)cc(OC)c1C +CNC(=O)NC(C)(C)C(=O)Nc1nnc(CC(C)C)s1 +COc1cc(CN2CCC3(C2)OCCO3)ccc1OCC(F)(F)F +COc1ccc(CNC(=O)COc2cccc(C)c2C)cc1 +O=C(Nc1ccc(F)cn1)c1cnc(-c2ccccc2)nc1 +CC(=O)OC1CCN(C(=O)c2cccc(C#N)c2)CC1 +CC1CCCCC1Nc1ncc(N)cc1Br +CC(NC(=O)C1(O)CCCC1)c1ccc(OCC(=O)NC2CC2)cc1 +CC(C)C1Nc2ccccc2C(=O)N1Cc1ccccc1 +CCNc1nc(Nc2ccc(C(N)=O)cc2)nc2ccccc12 +O=C(OCCNc1cccnn1)C1C2CCCCC21 +CC(=O)c1ccc(NC(=O)NC(C)(CO)C2CC2)cc1 +CCc1cccc(NC(=O)C2(C)Oc3cccnc3N(C)C2=O)c1 +Fc1cc(CNc2cnn(-c3ncccn3)c2)ccc1Br +OCCCNc1ncnc2onc(-c3ccc(F)cc3)c12 +COc1ccc(C(NC(=O)c2cc(C)nn2C)C2CCOCC2)cc1 +CCc1ccc(N)cc1S(=O)(=O)N(C)C1CCCC1 +CNS(=O)(=O)c1ccc(CNC(=O)NC2CCCCC2)s1 +Cn1c(=O)c(C(=O)NC2CCCC2)nc2cccnc21 +Cc1cc(NC(=O)c2cc(Br)ccc2N)no1 +c1cncc(-c2n[nH]cc2CN2CCCN(c3cccnn3)CC2)c1 +COCC(C)(NC(=O)c1cc(NC(C)=O)ccc1F)c1ccccc1 +CCCS(=O)(=O)NCC(OC)c1ccc(C)s1 +CCCCn1nc(C(=O)Nc2ccc(F)cc2F)ccc1=O +COC1C(COC(=O)C2CCCCC2)OC2OC(C)(C)OC21 +Cc1ccccc1-n1cc(C(=O)N(C)C2CCc3ccccc3C2)cn1 +CCc1nnc(COc2cc(Br)ccc2Cl)n1C +CC(OC(=O)Cc1ccc2c(c1)OCCO2)C(N)=O +COCCn1cc(NC(=O)COc2cccc3c2OC(C)(C)C3)cn1 +Cn1cncc1-c1nnc(C2CCN(Cc3cccc(C#N)c3)C2)o1 +COc1cccc(N2CCN(C(=O)Cc3sc(C)nc3C)CC2)c1 +O=C(NCc1ccccc1F)c1ccc2ncsc2c1 +O=C(Nc1cccc(N2CCNC2=O)c1)c1cccc(F)c1 +Cc1cc(NCCNC(=O)c2cnc(C3CC3)s2)n2ncnc2n1 +O=C(Cn1cnnn1)N(Cc1ccccc1)Cc1ccco1 +NC(=O)c1cc(NCC(=O)NC2CC2)ccc1F +CC(C)c1nc(CN2CCc3ccccc3C2)cc(=O)[nH]1 +COc1cccc(CNC(=O)c2cccc(C(=O)N3CCCC3)n2)c1 +CN(CCC#N)S(=O)(=O)N1CCOc2ccc(F)cc21 +COc1cc(O)c2c(c1)C(c1ccnnc1)NCC2 +CCOc1cc2c(cc1O)C(c1ccc(C)nc1)NCC2 +Cc1ccc(C(=O)NCC(=O)NC(C)CCc2ccco2)cc1 +N#CCc1nnc(C(N)c2ccc(F)c(F)c2F)o1 +COc1c(NC(=O)Nc2cn[nH]c2)c(C)nn1C +CCc1cccc(CC)c1NC(=O)Cc1ccc(NC(C)=O)cc1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)c1c(O)cc(F)cc1F +CN(CC(=O)NC(c1ccc(F)cc1)C1CCCC1)S(C)(=O)=O +CCc1noc(CC)c1CC(=O)NC1CC(C)(OC)C1(C)C +CC(C)c1csc(C2CC(=O)NCc3nc4ccccn4c32)n1 +CC(C)c1csc(NC(=O)c2cccc(N)n2)n1 +C=CCNC(=O)c1nn(-c2ccc(F)cc2)cc1OCC +COc1ccc(OC)c(NC(=O)c2cc(F)ccc2-n2cccc2)c1 +COC(=O)N1CCc2[nH]nc(-c3ccc(OC)cc3OC)c2C1 +Cc1ccc(C)c(OCCc2nc(C3CC3)c(CO)s2)c1 +COCC1CCCN(C(=O)c2cc(Cl)ccc2Cl)C1 +Cc1nc2ccc(N)cn2c1C(=O)OC1CCCCC1 +COc1cn(-c2ccc(F)cc2)nc1C(=O)NC1CC1 +O=C(OCc1noc(-c2ccco2)n1)c1ccccc1 +Cn1cc(Cl)c(C(=O)Nc2cc(Cl)cc(Cl)c2)n1 +COC(=O)c1ccc(CCNC(=O)c2c(C)noc2C(C)C)cc1 +COC(=O)CC1C(=O)NCCN1C(=O)Cc1cc(F)ccc1C +CS(=O)(=O)N1CCc2ccc(C(=O)NCc3cccs3)cc21 +CC(=O)NCCNC(=O)C(C)Oc1ccc(Cl)cc1C +Cc1cnc(NC(=O)C2CCN(C(=O)NC3CC3)CC2)s1 +CCCCCCSc1nnc(-c2ccoc2C)n1N +COc1c(N)ccc2c1N(C)S(=O)(=O)C21CCCCC1 +C=CCCCN(C)C(=O)Nc1ccnn1C(C)C +COC(=O)CSc1nc2ccccc2c(=O)n1CCC(C)C +CCN(CC(=O)OC)C(=O)Cc1c(F)cccc1Cl +CC(=O)NC(C)C(=O)N1CCCC1Cc1ccccc1 +Cc1ccc(-c2cc(=O)[nH]c(-c3cccnc3)n2)cc1 +N#Cc1ccsc1NC(=O)Cc1ccc(N2CCCC2=O)cc1 +Cn1ccnc1C(=O)c1ccc(NC(=O)C2Cc3ccccc3O2)cc1 +COc1ccc(C2CCCN2C(=O)c2ccc(=O)[nH]c2)cc1OC +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1ccc2[nH]cnc2c1 +CN(Cc1ccc(Cl)c(Cl)c1)C(=O)c1cnns1 +c1ccc(NCCCN2CCOC3CCCC32)cc1 +O=C(Nc1ccccc1C(F)(F)F)c1cn[nH]c1 +O=C(NCCc1nnc2ccccn12)c1ccccc1OC(F)F +O=C(Cc1ccc(OC(F)F)cc1)Oc1ccc(-n2cnnn2)cc1 +Cc1nc(CNC(=O)CSc2ccccc2)no1 +CCCOC(=O)C1C2C=CC3(CN(CC4CCCO4)C(=O)C13)O2 +CCOc1ccc(CN(C)C(=O)c2ccc3[nH]cnc3c2)cc1 +Cc1cccc(NC(=O)C2CSc3ncc(C)c(=O)n3C2)n1 +C1Cc2c(sc3nc(C4CC4)nn23)C(C2CC2)N1 +COc1ccc(C2(NS(=O)(=O)c3cn(C)c(C)n3)CCCC2)cc1 +O=C(Cn1nnc(-c2ccccc2)n1)NCc1ccc2ccccc2c1 +CS(=O)c1ccc(CNC(c2nccs2)C2CC2)cc1 +O=C(c1cc2ccccc2s1)N1CCN(C2CCCC2O)CC1 +N#Cc1nnn(-c2ccc(C(N)=O)cc2)c1C1CCC1 +COc1ccc(CNC(=O)Cn2nnc3ccccc32)cc1 +COc1cc(OC)c(-c2nn(C)c(C)c2N)c(OC)c1 +O=C(Nc1ccc(-n2cncn2)c(F)c1)N1CCCC1 +CC(=O)c1ccc(C(=O)N2CCSc3ncccc32)cc1 +O=c1ccc2ccc(OCc3cc(=O)n4ccsc4n3)cc2o1 +O=C(NC(CC1CCOC1)c1ccccc1)c1scnc1C1CC1 +COc1ccc(C(C)=O)cc1CN1CCOC2CCCCC21 +Cn1ccc(CNC(=O)c2ccc(Br)c(O)c2)c1 +CCOc1ccc(CNC(=O)C2COc3ccc(OC)cc3C2)cc1 +CC(C)C(=O)N1CCCC1C(=O)N1CCN(C(=O)c2ccco2)CC1 +Cc1c(C(=O)N2CCCC2)sc2ncnc(N3CCCCCC3)c12 +O=c1[nH]ccn2c(C(O)c3ccc(F)cc3)ncc12 +Cn1cc(C(=O)NCc2ccncc2)c2ccccc21 +Cc1ccc(CN(C)C(=O)CSc2ncn[nH]2)cc1 +CC(C)(O)CN(Cc1ccccc1)C(=O)NCC(F)(F)F +COc1ccc(C)cc1NC(=O)c1cc(S(N)(=O)=O)c(C)o1 +COCC(=O)Nc1nnc(CS(=O)(=O)c2ccccc2)s1 +Cc1ccc(S(=O)(=O)NCC(O)CN2CCOCC2)cc1 +CC(=O)c1cc(F)ccc1OCC(=O)NCc1ccccc1C +CCCC1CCC(NC(=O)CCn2nnc3ccccc3c2=O)CC1 +COc1cc(OC)c(NC(=O)c2ccnn2C)cc1F +CCN1C(Cl)=Nc2c(Cl)cccc2S1(=O)=O +COc1cc(Cl)c(C)cc1-n1nnc(C#N)c1C1CCC1 +CC(=O)Nc1cccc(NC(=O)c2csc(-c3ccsc3)n2)c1 +CCOc1ccnc2c1c(=O)n(Cc1ccccc1)c(=O)n2C +CCNC(=O)N1CCc2cc(S(=O)(=O)Nc3ccccc3)ccc21 +CC(C)C(NC(=O)c1ccnc2[nH]ccc12)C(=O)N1CCOCC1 +COc1cc(NC(=O)CN(C)c2ccccc2)cc(OC)c1OC +O=C(NCC1CN(Cc2ccccc2)CCO1)c1ccccn1 +O=C(NCc1nc2ccccc2s1)Nc1ccc2c(c1)CCC2 +Cc1cc(C)c(CNC(=O)N(Cc2ccc(F)cc2)C2CC2)c(=O)[nH]1 +CCN(CC)S(=O)(=O)c1ccc(NC(=O)CC2C=CCC2)cc1 +COc1ccccc1CNC(=O)C(NC(=O)C1CCCCC1)C(C)C +Cc1cccn2cc(CC(=O)Nc3c(C(N)=O)oc4ccccc34)nc12 +Cc1nnc2n1CC(CNc1nccc(C(F)(F)F)n1)CC2 +CCOc1ccc2cc(C(=O)N(C)CCC#N)[nH]c2c1 +CC(C)(C)c1cc(C(=O)Nc2ccc3c(c2)COC3)no1 +CCOC1CCCN(S(=O)(=O)c2c(C)cc(C)cc2C)C1 +CC(=O)c1ccc(OCc2ccccc2C)c(N)c1 +CCCn1cnnc1CNC(=O)c1cnc(Nc2ccccc2)nc1 +O=C(NCc1ccc2c3c(cccc13)C(=O)N2)c1ccccc1 +CSc1nnc(-c2cccn(Cc3ccccc3)c2=O)n1C +N#Cc1c2c(c(-n3ccnc3)n3c1nc1ccccc13)CCCC2 +CC(Nc1ccccc1S(C)(=O)=O)c1ccsc1 +NC(=O)c1cccc(CNC(=O)COc2cccc(F)c2)c1 +Cc1cc(C)n2nc(C(=O)NCCc3ccc4c(c3)OCO4)nc2n1 +COc1ncnc2c1CN(Cc1csc(-c3ccc(C)o3)n1)CC2 +CCNC(=O)COc1cccc(NC(=O)NCc2ccccn2)c1 +CC(C)C(=O)Nc1cccc(NC(=O)CNC(N)=O)c1 +COc1ccc(OC)c(C(=O)Nc2cc(-c3ccncc3)n[nH]2)c1 +Cc1ccn(Cc2nc(N)nc(N(C)C)n2)c(=O)c1C#N +CS(=O)(=O)N1CCC(NC(=O)CC(F)(F)F)CC1 +CC(C)c1cc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)nn1C +Cc1nc2ccccc2n1CCCNC(=O)C(C)(C)C +CCCN(Cc1ccc(C#N)cc1)C(=O)NC1CCOCC1 +Cc1cccc(C(C)C)c1NC(=O)Cc1ccc(-n2cnnn2)cc1 +CCC(CC)NC(=O)N1CCCC(c2nc(C)no2)C1 +CCc1nc(NCC(C)C)c2c(C)nn(-c3ccccc3)c2n1 +CC(C)S(=O)(=O)c1cccc(C(=O)Nc2ccccc2)c1 +CCOC(=O)c1ccc(Oc2ncnc3c2cnn3C)cc1 +COc1ccccc1CC(=O)Nc1cccc(NC(=O)C2CC2)c1 +CN(CC(=O)NC1CC1)c1nc(-c2ccsc2)nc2ccccc12 +COc1ccccc1CCNC(=O)C1CCCN(C(=O)NC2CC2)C1 +CCOc1ccc(-c2csc3ncnc(NCCO)c23)cc1 +NC(=O)C1CCN(C(=O)CSc2nc3ccccc3o2)C1 +N#Cc1ccc(Cn2ccc3ccc(O)cc3c2=O)cc1 +CCCOc1cccc2c1C(c1cnoc1C)NCC2 +COC1CCCCCC1NC(=O)NC1CC=CC1 +CSc1ccc(CNC(=O)c2sccc2C2CC2)cc1 +COc1ccccc1SCC(=O)N(CC(F)(F)F)C(C)C +CCn1cc(CN(C)C(=O)Cn2cc(C)c(N)n2)c(C)n1 +CCOC(=O)C(C)(N)Cc1c(F)c(F)c(F)c(F)c1F +COc1cccn(CC(=O)N2CCC3(CCCN(C)C3=O)C2)c1=O +CCC(=O)c1ccc(OCC(=O)N=c2[nH]nc3cc(C)ccn23)cc1 +CCOCCCn1c(=NC(=O)C2CC3CCC2O3)[nH]c2ccccc21 +CS(=O)c1ccc(NC(=O)Cc2cccc(F)c2F)cc1 +COc1ccc(C(=O)N2CC3CCCCC3C2)cc1-n1cnnn1 +CCCC(=O)Nc1cc(=O)n(-c2ccccc2)nc1C(=O)OCC +CCc1noc(C(C)N2CCN(CCN3CCCC3=O)CC2)n1 +Cc1cnc(C)c(-c2cccc(-c3ccn[nH]3)c2)n1 +O=C1C(NC(=O)N2CCOCC2C2CC2)CCCN1c1ccccc1 +COCCN(CC(N)=O)C(=O)c1cccc(F)c1Cl +CCn1nc(C)c(NC(=O)c2cnc3ccc(C)cn23)c1C +O=C(COc1ccc(Cl)cc1Cl)NCC1CCCO1 +O=C1CCC2(CCCN(C(=O)Cc3cccc(O)c3)C2)CN1CCO +O=C(c1cnc2n(c1=O)CCS2)N1CCCC1c1ccncc1 +CCCC(=O)NC1CCCN(C(=O)NCc2ccccn2)C1 +O=C(CCc1ccsc1)N(CC(F)(F)F)c1ccccn1 +CC(C)(C)n1cc(C(=O)NCc2cc(Cl)c3c(c2)OCCO3)cn1 +COC(=O)c1sc(NC(=O)Cn2ccccc2=O)nc1C1CC1 +CC(=O)Nc1cccc(NC(=O)Cc2c[nH]c3ccccc23)c1C +CC(=O)N1CCN(C(=O)CCNS(=O)(=O)c2ccccc2)CC1 +Nc1ccc(Cl)c(NC(=O)Cn2ccccc2=O)c1 +NC(=O)CSc1nccn1-c1cc(Cl)ccc1Cl +CC(=O)c1cc(Br)cc2c1OC(C)C(=O)N2C +CC1(C)COc2c(N)c(Cl)cc(Cl)c2NC1=O +Cc1nnc(SCCC(=O)NCc2ccco2)n1-c1ccccc1 +Cc1nn(CCO)c(C)c1-n1ccnc1-c1ccc(CO)o1 +O=S(=O)(NCc1ccnc(-n2cccn2)c1)c1cccs1 +CCC1CCCCN1C(=O)CCNC(=O)NCCc1ccccc1 +CC(C)Oc1cccc(Cn2cnc3sccc3c2=O)c1 +Cc1ocnc1C(=O)NCCCn1ccc2ccccc21 +CSc1ccc(Cl)c(C(=O)NC(C)c2nnc3ccccn23)c1 +Cc1nc(SCc2ccc(C(N)=O)cc2)c2ccccc2n1 +O=C(NCCCc1ccccc1)C1CCCN(C(=O)NC2CC2)C1 +COc1ccc(-c2nc(CNC(=O)NCc3ncn(C)n3)n[nH]2)cc1 +Cc1ccccc1C(=O)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +CN(C)C(=O)CN1CCN(Cc2cccs2)CC1 +O=C(Cc1ccc(F)c(F)c1)OCCNc1ncccn1 +Cc1ccc(Br)cc1NC(=O)c1ccc(=O)n(C)n1 +Cc1ccc(C)c(C(=O)N(C)Cc2ccncc2)c1 +COc1ccc(NC(=O)N2CCN(Cc3cccnc3)CC2)cc1 +COc1cc(CSc2nncn2C(C)C)ccc1SC +CCNc1nn(-c2nc(C)cc(C)n2)c2c1C(=O)CC(C)(C)C2 +N#Cc1cccc(NC(=O)CC(C#N)c2ccc(F)cc2)c1 +N#Cc1ccc(S(=O)(=O)c2ccc(Cl)cc2)o1 +CC1CCCCN1C(=O)CNC1=NS(=O)(=O)c2ccccc21 +COc1ccc(C(=O)N2CCCCC2C(N)=O)cc1Br +OCCNc1cc(-c2ccc(O)c(Cl)c2)c2cc[nH]c2n1 +COC(=O)N1CCCN(C(=O)Nc2ccc(F)cc2Cl)CC1 +Cc1ccccc1CC(C)NC(=O)CCn1cncn1 +COCC(O)CN(C)C(=O)c1cc2cc(C(F)(F)F)ccc2n1C +CCc1cc(NC(=O)c2cnc(Cc3ccccc3)s2)nc(C)n1 +NC(=O)c1oc2ccccc2c1NC(=O)c1ccc(C(F)(F)F)cc1 +CC(Cc1ccc(Cl)cc1)N(C)C(=O)c1ccc(F)nc1 +COCC(C)(O)CNS(=O)(=O)c1ccc2ccccc2c1 +Cc1nc(-c2ccc(F)cc2)sc1C(=O)Nc1cccnc1 +Cc1ccc2oc(C(=O)N(C)Cc3nc(-c4ccncc4)no3)cc2c1 +COc1ccc(NC(=O)C2(C#N)CCCC2)cc1N1CCCC1=O +Cc1cc(Br)ccc1SCC(=O)Nc1cn[nH]c1 +CC(C)CNC(=O)Cn1cc(Br)ccc1=O +Cc1nn(C)c(C)c1NC(=O)COc1cccc(Br)c1 +CC(=O)c1ccc(NC(=O)c2ccccc2-c2nc(C(C)C)no2)cc1 +CC(=O)Nc1ccc(C2NC(=O)c3ccccc3N2C)cc1 +COc1ccccc1OCCNC(=O)NCc1ccc(F)cc1 +CC(C)C(=O)NCc1noc(-c2ccsc2)n1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)N1CCOCC1CC(C)C +Cn1cccc1C(O)CNC(=O)c1c(F)cccc1Cl +O=C(NCCc1ccccc1F)N1CCN(c2ncccn2)CC1 +COc1ccc(N2CC(C(=O)NCCN3CCOCC3)CC2=O)cc1 +CCCOc1ccc(Cl)cc1C(=O)CCN1CCOCC1 +COc1ccc(C)cc1NC(=O)c1ccc(-n2ccnc2)nn1 +Cc1cc(C)c(C)c(OS(=O)(=O)c2cccc(-n3cnnn3)c2)c1 +O=C(Nc1nc2ccccc2s1)c1ccc2cc[nH]c2n1 +COc1cccc(Nc2cc(C(F)(F)F)cnc2N)c1 +O=C(Nc1cnc(N2CCCC2)nc1)c1cccc(Cl)c1 +O=c1[nH]c(Sc2ccccc2)nc2ccccc12 +CCc1cc(-c2ccncc2)nc(N2CCOCC2)n1 +CS(=O)(=O)c1ccc(NC(=O)c2cccc(-n3cnnn3)c2)cc1 +Cc1nc(-c2c[nH]c(C(=O)NC3(C#N)CCCCC3)c2)cs1 +Cc1cc(C(=O)CN(C)Cc2ccc(OC(F)F)cc2)c(C)[nH]1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2ccccc2C)cc1 +Cc1cc(NC(=O)c2ccc(F)c(F)c2)n(C)n1 +CCCS(=O)(=O)N1CCC(NC(=O)OC(C)(C)C)C1 +C#CCn1nc(CO)cc1-c1cc(C)ccc1OCC +N#Cc1nc(-c2ccccc2)oc1N1CCCCCC1=O +Cc1occc1CN(C)C(=O)Nc1ccc(Br)cc1F +CC(C)c1ccc(OC(=O)CSc2nnnn2C2CC2)cc1 +COc1ccccc1CC(=O)N1CCN(C(=O)c2ccccc2)CC1 +CN(C)C(=O)CN1CC2CN(c3ncccn3)CC2C1=O +CCOCC1CCCN(C(=O)C(CC(C)C)N2CCCCC2=O)C1 +COc1ccc(NC(=O)c2cccc3c2SCCC3=O)cc1OC +Cn1cnc2ccc(NC(=O)c3cc(=O)[nH]c4ccccc34)cc2c1=O +CC1CCN(c2ccc(S(C)(=O)=O)cc2S(C)(=O)=O)CC1 +CCOC(=O)C1CCN(S(=O)(=O)NC2CCCC(CC)C2)CC1 +O=C(NCC(O)CO)Nc1cccc2cnccc12 +COc1ccc(-n2ccnc2SCc2cc(C)on2)cc1 +N#Cc1ccc(Sc2nnc(NCCc3cccs3)s2)nc1 +Cc1n[nH]c2c1C(c1c(F)cccc1Cl)C1=C(COC1=O)N2 +Cc1csc(C(C)NC(=O)Nc2ccccc2Cn2cccn2)n1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(N2CCOCC2)nc1 +Cc1noc(CCC(=O)NC(C)c2ccc3c(c2)CCCC3)n1 +Cc1nc(C2(NC(=O)c3ccc(OCC4CC4)nc3)CCCC2)no1 +COCC(=O)N1CCCC(c2cc(C(F)F)n3ncnc3n2)C1 +Fc1ccc(OC(F)F)c(NCc2nnnn2-c2ccccc2)c1 +N#Cc1cccc(NC(=O)CCSc2ccc(O)cc2)c1 +CS(=O)c1nncn1-c1ccnc(Cc2ccccc2)n1 +COCCN(CC(C)C)C(=O)Nc1nc2ccc(OC)cc2s1 +CC(C)OC(=O)CN1C(=O)COc2cc(Br)ccc21 +Cc1oc(C(=O)NC(c2ccccc2)C(C)C)cc1S(N)(=O)=O +CCNC(=O)NC1COC2C(Nc3nccc(C(C)(C)C)n3)COC12 +Nc1ccc2c(c1)N(CC(=O)Nc1ccccc1F)CC2 +Cc1ccccc1OCC(=O)Nc1ccc(Cl)c(C(N)=O)c1 +CCOC(=O)CN1CCCn2nc(C(=O)N3CCOCC3)cc2C1 +COCc1nc(C(=O)Oc2ccc(Cl)cc2C)cs1 +CC1Oc2ccc(C(=O)CN3CCC(=O)CC3)cc2NC1=O +Cc1occc1C(=O)N(C)Cc1nc(-c2ccc(Cl)cc2)no1 +CCC(CC)c1nnc(NC(=O)C(C)NC(C)=O)s1 +CC(Cc1ccccc1Cl)NC(=O)NCC1CCOC1 +Cc1c(NCC(=O)Nc2ccccc2F)cccc1NC(=O)C1CC1 +CC(NC(=O)C1COc2ccc(F)cc2C1)c1nc(C(C)(C)C)no1 +Cn1c(C(=O)NCCNC(=O)OC(C)(C)C)cc2ccccc21 +CC(C)CN1CCOC(CNC(=O)Cc2ccc3c(c2)CCC3)C1 +CS(=O)(=O)NC1CCN(Cc2ccncc2)C1Cc1ccccc1 +Cc1nc(N(C)C)sc1CN1CCN(C(C)c2ccccn2)CC1 +CCN(Cc1ccccc1C#N)C(=O)CNC(=O)OC +CCNC(=O)CN1C(=O)CCCc2sccc21 +N#Cc1cc2c(nc1SCC(=O)NCCc1ccccc1)CCC2 +O=C(NCC1CN2CCCCC2CO1)c1cc2cc(Cl)ccc2o1 +O=C(NCCc1cccs1)c1ccc2nnc(C(F)F)n2c1 +Cn1nc2n(c1=O)CCN(Cc1nc(-c3ccc(F)c(F)c3)no1)C2 +Cc1nn(C)c2ncc(NC(=O)C3CCCC3)cc12 +CC(C)c1ccc(C(=O)NC(C)(CO)CO)cn1 +O=S(=O)(c1ccc(Cl)c2ccccc12)N1CCCC1 +COc1ccccc1OCC(=O)N1CCOCC1(C)C +C=C(C)CN(CC)C(=O)C1CC(=O)N(c2ccc(OC)cc2OC)C1 +COC(=O)Cc1csc(NC(=O)c2ccc3[nH]ncc3c2)n1 +CNC(=O)NCC(=O)NCc1sc(-c2ccccc2)nc1C +CCN(Cc1ccn(C(C)C)n1)C(C)c1ccc(C#N)cc1 +O=C(NCCC(O)c1cccs1)Nc1ccccc1C(F)(F)F +CC1(C)Cc2cccc(OCC(=O)N3CCNCC3)c2O1 +CC(c1ccccc1F)N(C)C(=O)c1csc(-c2ncccn2)n1 +CS(=O)(=O)N1CCCC(NC(=O)Nc2ccc3c(c2)OCO3)C1 +COc1cccc(C(NC(=O)c2cccs2)c2nccn2C)c1 +Cc1ccc(CC(=O)Oc2ccc(OCC3CC3)cc2)cn1 +CC(C)NC(=O)Nc1nc(-c2ccccn2)cs1 +CCCCNC(=O)CN1CCN(c2ncccc2C(N)=O)CC1 +O=C(NCCc1ccc(F)cc1)C1CN(C(=O)c2cnccn2)C1 +Cc1cccn2c(C(C)O)c(-c3ccc4c(c3)OCCO4)nc12 +COCCN(Cc1occc1C)CC(F)(F)F +CC(Oc1cccc(-c2ccccc2Cl)c1)C(N)=O +CC(=O)c1cccc(NCC(=O)NCCc2ccc(F)cc2)c1 +Cc1nc(C#N)c(-c2ccc(Br)cc2)o1 +O=C(NCc1nccn1Cc1ccccc1)Nc1ccc2c(c1)COC2 +CC1(C)OC2C(CCCO)OC(OCc3ccccc3)C2O1 +Cc1cc(=O)[nH]c(-c2ccccc2C(F)(F)F)n1 +O=C(NCc1cc(Br)cs1)NC1CCCCNC1=O +CN1C(=O)CC(C)(C)Oc2ccc(C(=O)NCCO)cc21 +Cc1nc(SCCCCC(N)=O)c2c(C)c(C)sc2n1 +NC(=O)c1ccc(Cn2c(-c3ncccn3)noc2=O)cc1 +CCc1onc(C)c1NC(=O)Cc1csc(-c2cnccn2)n1 +COCC(O)CN(C)c1cnc2cc(Cl)c(Cl)cc2n1 +Cc1cc(NC(=O)C2CCN(S(C)(=O)=O)CC2)n(C)n1 +O=C1NCCCCC1Sc1ccc2c(c1)OCCO2 +Cc1n[nH]cc1CNc1ccc(-c2nccs2)cc1 +COc1cccc(CC(C#N)C(=O)NCC(C)C)c1 +NC(=O)C1CCCN(C(=O)Cc2ccc(-n3cccn3)cc2)C1 +Cc1ccc(NC(=O)NC(C)c2ccco2)cc1S(C)(=O)=O +O=C(NCC(F)F)Nc1ccccc1CN1CCNC1=O +CC1CN(C(=O)CNc2ccc(F)c(C(N)=O)c2)CC(C)O1 +Cc1cc(NC(=O)CCC#N)ccc1Br +NC(=O)c1cc(S(=O)(=O)N2CCCc3ccccc32)cs1 +CSc1ccc(C#N)cc1NCC(=O)Nc1cc(C)nn1C +CN(C)C(=O)c1cccc(CNc2cn[nH]c(=O)c2Cl)c1 +Nc1ccc(-c2nc3cc(Cl)cnc3o2)c(Cl)c1 +CC(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O +Nc1cc(=O)[nH]c(Cc2ccccc2Br)n1 +COC(=O)C(C)n1cnc2c(cnn2-c2ccc(F)cc2)c1=O +CN(C)c1nc(CN2CCCN(CC(F)F)CC2)ns1 +CCCCNC(=O)N1CCN(C(=O)Cc2ccccc2F)CC1 +CC(C)NC(=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1Cl +Cc1ccccc1CCNC(=O)Cc1ccc(N2CCCC2=O)cc1 +Cc1nnc(NCc2ccc(C(C)(C)C)cc2)s1 +O=C(NCc1ccncc1)N1CCN(c2ccccc2O)CC1 +Cc1ccc(C(=O)NCCCc2nc(CC(C)C)no2)cc1F +O=C(Cn1nc(-c2ccco2)oc1=O)Nc1c(F)cccc1F +COCc1ccccc1NC(=O)NC1CCCC1C(=O)OC +CC(C(=O)N(c1nccs1)C1CCCCC1)N1CCOCC1 +Cc1c(C(=O)N(C)CC(N)=O)oc2ccc(F)cc12 +COc1cccc(-c2ncc(CNC(=O)c3cn[nH]n3)s2)c1 +CNC(=O)c1cc(C)ccc1NC(=O)CCOC +O=C(NCCCOC1CCOCC1)c1ccc(-c2cscn2)cc1 +COCCNc1nc(C)cc(N2CCC(=O)CC2)n1 +CCc1nc2cc(NC(=O)c3ccccc3S(C)(=O)=O)ccc2o1 +O=C(NCCc1cccnc1)c1coc(COc2ccccc2F)n1 +Cc1c(C(=O)N2CCCCC2C)[nH]c2c1C(=O)CC(C)(C)C2 +COc1cc(C)c(C(=O)CN2CCOCC2)c(C)c1 +Cc1ccc(N)cc1NC(=O)CCCSc1ccccc1 +COc1ccc(COC(=O)C(C)CC#N)cc1C(C)C +CCc1nc(COC(=O)CCc2ccccc2)cs1 +COc1ccc(OC)c(NC(=O)c2nc(-c3cnccn3)no2)c1 +CC(C)N(C)C(=O)C1CCN(C(=O)CC=Cc2ccccc2F)CC1 +CCCn1c(=O)cc(Nc2cccc(Cl)c2C)[nH]c1=O +CCC(=O)N1CCCC1C(=O)c1cc(F)ccc1F +O=C(Nc1ccc(F)cc1Cl)c1scnc1C1CC1 +Nc1c(-c2ccncc2)noc1C(=O)Nc1nccs1 +Cc1cc2n(n1)CCC(=O)N2C(C)C(=O)NC(C)C +O=C(Nc1ccc(S(=O)(=O)N2CCCC2)cc1)C1CC1 +CC(C)(C)n1cc(NC(=O)CCOc2ccccc2)cn1 +CCCNS(=O)(=O)c1ccc2c(c1)NCC(CC)O2 +CC1CCCN(S(=O)(=O)N2CCCC2c2nnc3ccccn23)C1 +O=S(=O)(NCc1ccccc1)c1cccc(Cl)c1 +CCOc1ccc(C(=O)NCC(=O)N2CCN(CC)CC2)cc1 +Cn1ccnc1SCCNc1ncnc2c1oc1ccccc12 +N#Cc1ccc(S(=O)(=O)N2CCCC(C(N)=O)C2)cc1 +Cc1ccc(NC(=O)NCc2cnn(C)c2)cc1Br +CC(=Cc1ccc2c(c1)CCO2)c1nc2sccc2c(=O)[nH]1 +Cn1nc2nc(N3CCCC3)nc(-c3ccc4c(c3)OCO4)c2c1N +CN(C)S(=O)(=O)c1cccc(CN2CCOCC2)c1 +CCn1ncc(Cl)c1-c1nn2c(C)nnc2s1 +Cc1ccc(OCCN(C)C(=O)c2ccccc2F)cc1 +Cc1csc(C(C#N)C(=O)C(NC(=O)c2cccs2)C(C)C)n1 +c1ccc2c3c(ccc2c1)CCNC3C1CCCO1 +COc1ccc2nc(NC(=O)Cc3c(C)nc(C)[nH]c3=O)sc2c1 +COC(=O)N1CCCC(NC(=O)NCCc2ccc3c(c2)OCO3)C1 +COc1ccc(C(=O)Nc2nc3ccc(NC(C)=O)cc3s2)cc1 +Nc1ccc2nc(-c3ccccc3)n(CCO)c2c1 +CCNC(=O)CN(C)C(=O)c1cc(Cl)ccc1Cl +Cc1cc(C)cc(OCCNC(=O)c2c[nH]c(=O)n(C)c2=O)c1 +CNC(=O)c1ccc(Cl)c(NC(=O)Cc2ccccc2F)c1 +CC(C)(C)C(=O)Cn1cnc2scc(-c3ccccc3)c2c1=O +O=C(NCCCc1ccccc1)NCC(O)c1ccc2c(c1)CCO2 +CC(NC(=O)c1ccc(N2CCCC2=O)cc1)c1ccccc1 +Nc1ccc2c(N)c(OC(=O)Nc3ccccc3)ccc2c1 +CCOC(=O)N1CCCC(C(=O)Nc2nc(C(C)=O)cs2)C1 +C=CCNC(=O)CNC(=O)C(C)Oc1cccc(C)c1 +C=CCOc1cc(C(=O)NCc2c(C)nn(C)c2C)cc2occc12 +Cc1ccc(OCCNC(=O)c2nccnc2N)c(C)c1 +CCCc1cc(C(=O)N(C)Cc2nc(-c3ccccc3)cs2)[nH]n1 +CC1CCc2ccccc2N1CCC(=O)NC1C=CC(CO)C1 +Cc1ccc(Cl)cc1NC(=O)c1cn2ncnc2nc1C +N#Cc1c(N2CCCC2c2nnc3n2CCCCC3)nc2ccccn12 +CCC(C)N(C)C(=O)NCC(C)(C)c1ccncc1 +CC(C)c1cc(Br)cc2c1NC(=O)C2=O +CS(=O)(=O)c1ccc(N2CCOCC2)c(S(C)(=O)=O)c1 +Cc1cc(N)nc(SCC(=O)c2ccc(Br)cc2)n1 +NC(Cn1cccn1)c1cc(Br)ccc1F +Cc1ccc(CNC(=O)CCc2c[nH]c3ccccc23)n1C +CC(C)N(C)S(=O)(=O)NCc1coc(-c2cccs2)n1 +Cc1ccc(CC(=O)NCc2ccc(CN3CCCC3=O)cc2)cc1 +c1ccc(-c2ncc(CN3CC(c4cccnc4)C3)s2)cc1 +COc1ccc(NC(=O)c2cc3n(n2)CCCO3)cc1Cl +CCC(C)(CC)NC(=O)CCC(=O)c1ccc2c(c1)OCCO2 +COC(=O)c1ccc(OCc2ccccc2)c(O)c1 +Cc1ccc(C(=O)CCC(=O)Nc2ccc(F)c(F)c2)s1 +Cc1nc(-c2ccccc2)sc1C(=O)OCC1CCC(=O)N1 +CCC(CC#N)NC1CN(C(=O)OC(C)(C)C)C1 +Cc1noc(COC(=O)c2cnn(-c3ccccc3Cl)c2)n1 +CCC(C)NC(=O)NCC(=O)N1CCCc2ccccc21 +O=C(Oc1cccc(Br)c1)c1cnc2ccccn2c1=O +Nc1ccccc1S(=O)(=O)Nc1ccc(Br)cn1 +COc1cc(C#N)ccc1OCC1CCN(C(=O)OC(C)(C)C)C1 +Cc1ccccc1OCC(=O)Nc1ccccc1CC(N)=O +CC1(C2CCCN(Cc3cc(F)ccc3C#N)C2)OCCO1 +O=C(CSc1nnc(C2CC2)o1)NCC1CCCO1 +CS(=O)(=O)N1CCN(C(=O)CCCn2cncn2)CC1 +N#CCSc1ccsc1C(=O)Nc1ccc(F)cc1 +Cc1ccc(C)c(C(=O)OCC(=O)Nc2ccc3c(c2)OCCO3)c1 +NC(=O)CN1CCN(C(=O)c2cccs2)CC1 +CCCNS(=O)(=O)c1cc2n(c1)CCCN(CC)C2=O +Cc1cccc2nc(CSc3nnc(C(C)(C)C)n3N)cc(=O)n12 +O=C(NCc1ccccn1)NCC1(c2ccccc2)CCCC1 +CC(C)Cc1nc(CN(Cc2ccccn2)S(C)(=O)=O)no1 +CCOC(C)C(=O)Oc1ccc(C#N)cc1Cl +Cc1ccc(C(C)NC(=O)N2CCCC(NS(C)(=O)=O)C2)o1 +COCC1CCCCN1C(=O)c1c(C)nn(C)c1C +COc1cc(CNC(=O)NC2CCc3c(Cl)cccc32)ccn1 +Cc1ncsc1CCN(C)C(=O)C1Cc2cc(Cl)ccc2N1 +CNC(=O)C1CCCN1C(=O)c1ccc(C)cc1O +CC(C)OC(=O)CCNC(=O)N1CCC(C(=O)c2ccccc2)CC1 +O=C(c1ccccn1)N1CCCN(c2cnc3ccccc3n2)CC1 +CC(C#N)Sc1nc(-c2ccccc2Br)n[nH]1 +COCCNC(=O)c1ccc(NC(=O)c2ccc(OC)cc2)cc1 +C#CCNc1cc(S(=O)(=O)N2CCCCC2)ccc1N(C)C +CCOc1cccc(C2CC2Nc2cc(C)nc(C)n2)c1 +CN1CCN(C(=O)c2cnc3c(cnn3Cc3ccccc3)c2)CC1 +CC(C)(C)CC(=O)Nc1ccc(N2CCCC2=O)cc1 +Fc1ccc(C2=Nn3c(nnc3-c3ccco3)SC2)cc1 +O=C(Nc1ccccc1)C(Cc1ccccc1)n1cnnn1 +COC(=O)N(C)CC(=O)NCc1cccc2c1OCO2 +Cc1cccnc1NC(=O)c1nc(-c2cnccn2)no1 +CC(=O)Nc1cccc(CNC(=O)C2CCOC2)c1 +COc1cc(NC(=O)CCn2cc(C)cn2)cc(OC)c1OC +Cc1cc(C(=O)NCc2ccc(COCC(F)(F)F)cc2)on1 +COc1cc(CCNC(=O)N2CCCC2C(C)(C)O)ccc1F +Cc1ccc(S(=O)(=O)N(C)CCCC#N)cc1 +Nc1oc2c(c1C(=O)c1ccncc1)COc1ccccc1-2 +O=c1c(-c2nc(-c3cc4ccccc4o3)no2)cnc2ccccn12 +COc1c(C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)c(C)nn1C +O=C(COc1ccc2ccccc2c1)NCC(O)c1cccs1 +CN(C)C(=O)CNC(=O)NC1CCN(c2ccccc2)CC1 +O=C1CN(C(=O)c2cscn2)c2ccncc2N1 +CC(O)(CNC(=O)c1cccc(C#N)c1)c1ccc2c(c1)OCO2 +CCc1oc(-c2ccc(OC)c(OC)c2OC)cc1C(C)=O +CC(C)(C)OC(=O)NC1(c2noc(-c3cc(C4CC4)[nH]n3)n2)CCC1 +CC(C)(C)OC(=O)N1CCN(c2cc(C(F)(F)F)ccn2)CC1 +CC(C)c1ccc(CN(CCC#N)Cc2ccccn2)cc1 +CN(Cc1ccc(O)cc1)C(=O)C1CC1c1ccco1 +COc1cccc(C(=O)N2CCCN(C(N)=O)CC2)c1F +O=C(c1ccccc1)C1CCN(C(=O)c2cccs2)CC1 +Cc1ccc(Cn2c(CNC(=O)C3CC3)nc3ccccc32)cc1 +O=C(NCCCn1cncn1)Nc1ccccc1Cl +CC(C(=O)NCc1ccnc(OC2CCC2)c1)c1ccsc1 +CCCCCn1c(N(C)C)nc2c1c(=O)[nH]c(=O)n2C +CN(C(=O)C1Cc2cc(Cl)ccc2O1)c1nccs1 +CCOC(=O)C1CCCN(C(=O)c2cn(C)c3ccccc23)C1 +CCCN(Cc1cc2cccc(C)c2[nH]c1=O)C(=O)c1ccccc1 +COC(=O)Cn1nc(-c2cccs2)ccc1=O +C#CCNC(=O)CSc1nnc(C2CC2)n1Cc1ccccc1 +CC(=O)NCCNC(=O)N(C)Cc1ccccc1F +CCOc1ccc(CNC(=O)NCC(=O)NC2CC2)cc1F +COc1ccc(OCC(=O)Nc2ccnc(C)c2)cc1 +CCOC(=O)c1cnc(SCC(=O)NC2(C#N)CCCC2)nc1N +Cc1cc(Oc2ncccc2C#N)ccc1NC(=O)C1CCC1 +CNC(=O)c1nnc2ccc(-c3cccs3)nn12 +Cc1ccc(F)c(NS(=O)(=O)c2c(C)noc2C)c1 +Cc1cccc(C(=O)NCCc2ccccn2)c1O +O=C(Nc1ccc(F)c(F)c1)N1CCC(Oc2ccccc2)CC1 +Cn1cc(N2CCN(C(=O)c3cc(F)ccc3O)CC2)cn1 +Nn1c(SCCCc2cn[nH]c2)nnc1-c1ccccc1F +COc1ccc2oc(CNc3cc(C(N)=O)ccc3OC)cc2c1 +N#CC1(C(=O)N2CCCn3c(nnc3Cn3cnnc3)C2)CC1 +OCc1cccnc1NCc1ccc(Cl)cc1F +O=C(NCC1(CO)CC1)c1ccc(-c2ccccc2)cc1 +Cc1c(C(=O)Nc2cc(F)c(F)c(F)c2)cnn1C +Cc1cccc(N2CCN(S(=O)(=O)c3cn(C)nc3C)CC2)c1C +CC(C)(C)OC(=O)Nc1cc(N)c2ccccc2c1 +CC(C(=O)Nc1ccc(F)c(N)c1)n1cc(Br)cn1 +COc1cccc(CNC(=O)c2cc(-c3ccc(C)cc3)[nH]n2)c1 +Cc1noc(NC(=O)c2ccc(OCc3cscn3)cc2)n1 +CC(Sc1nnnn1C1CC1)C(=O)NCc1cscn1 +Cn1cc(N2CCN(Cc3ccsc3)CC2=O)cn1 +COCCNc1nc2sc3c(c2c2ncnn12)CC(C)CC3 +COC(=O)c1nn(Cc2noc3c2CCCC3)c(C)c1Cl +COc1ccc(NC(=O)Cc2ccccc2Cl)c(N)c1 +CC(c1cccs1)N(C)C(=O)c1cc(C(N)=O)cs1 +Cn1cc(C(=O)Nc2cccc(S(C)=O)c2)c(C(C)(C)C)n1 +CC(=O)c1ccccc1NC(=O)CCc1ccccc1 +CCCn1c(SCC(=O)NC2CC2)nnc1-c1cccc(C)c1 +Cc1cnn(CC2CCCCN2Cc2nnc(C3CC3)n2C)c1 +Cn1cc(NC(=O)Cc2cn(C)c3ccccc23)cn1 +COc1ccccc1-c1csc(NC(=O)c2cccn2C)n1 +COc1ccccc1-c1cc(=O)n2ncc(C(C)C)c2[nH]1 +COc1cc(=O)[nH]c(SCC(=O)Nc2[nH]c(C)c(C)c2C#N)n1 +Cc1nc(C(=O)N2CCC3(CC2)Nc2ccccc2NC3=O)cs1 +COc1cccc(C(=O)NCCCn2ncc3c(Cl)cccc32)c1 +CCOC(=O)CCN1CCCC1c1cccs1 +Cc1noc(C)c1C(=O)Nc1ccc2oc(C3CC3)nc2c1 +Cc1cccc2c(C(N)=O)cc(N3CCCC3)nc12 +O=C(Nc1noc2ncccc12)c1ccc2c(c1)OCCO2 +CCOCc1ccccc1NC(=O)N(C)c1c(C)noc1C +Cn1ccc(NC(=O)NCC2(CN3CCOCC3)CCCCC2)n1 +CC(C)(C)n1ncc2c1NC(=O)CC2c1ccc(F)c(F)c1 +Cc1c(Cl)cccc1NC(=O)c1cn(C)c2ccccc2c1=O +CC(=O)NCCNC(=O)NCCc1cnn(C)c1 +O=C(CCc1ccc(=O)n(Cc2ccccc2)n1)Nc1ccncc1 +Cc1cc(NC(=O)c2cc(-c3ccccc3)n[nH]2)sn1 +CC(=O)Nc1ccc(C)c(NC(C)c2nc(C3CC3)no2)c1 +CC(C)C(=O)N1CCCC(C(=O)NCCNc2cnccn2)C1 +Nc1cnn(CCc2ccc(Cl)cc2Cl)c1 +CC(C)c1noc(CCNC(=O)Cc2c(Cl)cccc2Cl)n1 +Cc1cccc(NC(=O)c2cc3ccc(O)cc3oc2=O)n1 +Cc1nnc(SCC(=O)NCC2CCN(c3ccccc3)C2)n1N +Cc1ccc(NC(=O)C(C)n2nnc(-c3ccccc3)n2)cc1F +COc1cc(S(=O)(=O)N2CCCCC2)ccc1F +O=C(NCC1(c2cccs2)CCCC1)c1ccno1 +CCCNC(=O)c1nnc2ccc(-c3ccccc3)nn12 +O=C(c1ccc(CS(=O)(=O)N2CCCC2)cc1)N1CCOCC1 +Cc1nnc(CNC(C)C(C)c2ccccc2)n1C1CC1 +CCOCCCNC(=O)C1CC(=O)N(C2CC2)C1 +Cc1sc(-c2ccco2)nc1C(=O)Nc1ccc(C#N)cc1 +Cc1nnc(SC(C)C(=O)Nc2ccc(C(F)(F)F)cc2)s1 +CS(=O)(=O)NCC(=O)N1CCC(Cc2ccccc2)CC1 +CCc1cc(Sc2ccc(O)cc2)n2ncnc2n1 +Nc1ccc(=O)n(CCCOCC2CCCCO2)c1 +Cc1cccc(OCC(C)NC(=O)c2cccc(NC(N)=O)c2)c1 +CC(C)NC(=O)CN1CCN(CC(O)CN2CCOCC2)CC1 +Cn1nc(C2CC2)nc1Cc1ccccc1Br +COc1cccn(CC(=O)N(C)CCC2CCOCC2)c1=O +CCOc1ccccc1Nc1nnc(SCC(N)=O)s1 +COc1ccc(C(=O)N(CC(F)(F)F)C2CCOCC2)cc1 +Cc1cccc(NC(=O)CNC(=O)C23CC4CC(CC(C4)C2)C3)n1 +CS(=O)(=O)NCC(=O)NC1CCN(c2ccccc2)CC1 +CC(=O)c1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)n2)cc1 +CCC1COCCN1C(=O)c1cnc(C(C)C)nc1C +COc1ccc(Oc2ncccc2NC(C)=O)c(C(N)=O)c1 +CCNC(=O)CNC(=O)Nc1ccc(Cl)cc1C +O=C(NCc1cc(F)ccc1Br)c1cscn1 +COc1ccc(-c2csc(-c3cccnc3)n2)c(OC)c1 +COCCNC(=O)CCNC(=O)c1cccc(C)c1 +CCc1ccccc1NC(=O)C1CCN(c2cnccn2)CC1 +CN(CCCNC(=O)C1COc2ccccc2C1)c1ccccc1 +CCN(CC)C(=O)CCC(=O)N1CCCN(C(C)=O)c2ccccc21 +Cc1nn(C)c(C)c1OCC(=O)Nc1cc(F)ccc1-n1cccn1 +Cc1ccccc1SC1CCN(C(=O)c2cnccc2C)CC1 +C#Cc1cccc(N(C)C(=O)c2sc(C)cc2OC)c1 +COC(=O)c1cccc2c1CCCN2C(=O)c1ccoc1C +CCn1cc(C(=O)Nc2ccccc2OCCOC)cn1 +Cc1cnn(CCC(=O)N2CCCC(n3cc(C)cn3)C2)c1 +CSc1ccc(NC(=O)N(CCC#N)CCC(F)(F)F)cc1F +Cn1cc(NC(=O)NCc2cccc(C#N)c2)cn1 +Cc1nccnc1S(=O)CC1CCN(C(=O)OC(C)(C)C)CC1 +Cc1csc(N2CCCN(Cc3cncs3)CC2)n1 +CCOC(=O)c1sc(NC(=O)c2ccn(C(C)C)n2)nc1C +CS(=O)(=O)N1CCCN(C(=O)Cc2cccc(F)c2F)CC1 +CCC(=O)N1CCCCC1C(=O)Nc1ccc(F)cc1OCC1CC1 +CCC1CCCCN1C(=O)c1cnc(N(C)C)nc1N +CSc1ccc(CNc2cnccc2C#N)cc1 +O=C(CN1CCN(c2ccccc2)CC1)N1CCCCC1 +Cc1ccsc1C(=O)NCC(=O)N1CCN(c2ccccc2)CC1 +CC(Oc1ccc(C#N)cc1)C(=O)Nc1ccccc1OC(F)F +COC(=O)c1sc(NC(=O)C2(C#N)CCCCC2)nc1C1CC1 +Cc1occc1C(=O)N1CCCC(NS(C)(=O)=O)C1 +CC(C#N)Sc1nnc(COc2ccc(C(C)(C)C)cc2)n1N +N#Cc1cccc(NC(=O)c2cn3cc(N)ccc3n2)c1 +CC1CCC(N(C)C(=O)Cn2nc(-c3ccccc3)ccc2=O)CC1 +Cc1cc(NC(=O)NC(C)c2cccnc2)n(C)n1 +C=CCOc1cccc(NC(=O)N2CCC3(CC2)OCCO3)c1 +COc1ccc(F)cc1NC(=O)CNc1ccc(C#N)cc1 +Cc1cccc(C)c1OCCCNC(=O)C1CC(=O)N(C)C1 +O=C1CN(Cc2cc(Cl)ccc2F)C2CCCCC2N1 +CN(C(=O)C1CC1)c1ccccc1C(=O)Nc1nc[nH]n1 +CNC(=O)c1ccnc(C23CC4CC(CC(C4)C2)C3)c1 +O=C1C2(Cc3ccccc3)CN3CCN(C2)CC1(Cc1ccccc1)C3 +CCC(C)n1c(C(C)O)nc2cc(C(F)(F)F)ccc21 +Cc1c(-c2cc(C(F)(F)F)nn2CCC#N)cnn1C +Cc1cc(C)n(CCC(=O)NCc2ccc3c(c2)OCO3)n1 +O=C(Cc1c[nH]cn1)N1CCC2(CCCN(C3CCOCC3)C2=O)C1 +COC(=O)CCNC(=O)Cn1ccc2ccc(F)cc21 +Cc1c(S(=O)(=O)Nc2ccc(OC(F)(F)F)cc2)cnn1C +CC1CCN(C(=O)Cn2cnnn2)C(c2ccco2)C1 +Cc1nn(C)c(C)c1NC(=O)C(C)N(C)CCC#N +Cc1cc(C)c(NC(=O)CNc2cc(C(N)=O)ccc2C)c(C)c1 +COC(=O)C1CCN(C(=O)c2cnc(Cc3ccccc3)s2)CC1 +O=C(CCn1ccccc1=O)Nc1ccn(-c2ncccc2Cl)n1 +COc1cccc(S(=O)(=O)CC(=O)N2CCCC2)c1 +CC(C)NC(=O)Nc1ccccc1C(=O)N1CCNC(=O)C1 +COc1ccccc1C(N)c1nc2ccccc2n1CC(C)O +Cc1cc(C)c(NC(=O)Cn2cnc3oc(C)c(C)c3c2=O)c(C)c1 +COc1ccc2c(cnn2CCC(=O)NC(C)C)c1 +c1ccc(OCc2nc(CCn3cnc4ccccc43)no2)cc1 +CCCCN(CC)S(=O)(=O)c1cc(C)cc(N)c1 +NC(=O)c1ccc(CNCC(O)c2ccccc2)s1 +CCS(=O)(=O)N1CC2(CCN(C(=O)c3cccnc3)C2)C1 +CCC(=O)CSc1nnc(Nc2ccc(OC)cc2)s1 +OCC1(CN2CCCc3ccccc32)CCOCC1 +CCNC(=O)CCc1ccc(S(=O)(=O)NC(C)C)cc1 +O=C(Nc1ccccc1C(=O)NC1CC1)c1cccc(-c2ccoc2)c1 +C#CCNC(=O)N1CCC(NS(=O)(=O)c2ccc(F)cc2)CC1 +CCOc1ccc(F)c(C(=O)OCc2nc(C)c(C)s2)c1F +CC1CCCN(C(=O)Nc2ccc(-n3cccn3)nc2)C1 +CCC(C)n1c(=O)[nH]c(C)c(Br)c1=O +CNc1ccc(Cl)c(C(=O)N2CCCC(CO)C2)n1 +Cc1nn2ncc(C(=O)NCc3ccccc3-c3ccsc3)c2[nH]1 +Cn1ccc(C(=O)NCc2cccc(NC(=O)C3CCC3)c2)cc1=O +CC(C)c1nc2c(c3c1COC(C)(C)C3)C1=NC=NC(=O)C1O2 +CSc1ccc(NC(=O)C(C)Sc2nncn2C(C)C)cc1 +CCN1C(=O)C(O)(CC(=O)c2cc3ccccc3o2)c2ccccc21 +CC(NCC(=O)NC1CCCCNC1=O)c1ccc(Cl)cc1 +C=CCNC(=O)c1ccc(Br)cc1O +O=c1[nH]nc(SCc2nc3ccccc3s2)n1C1CC1 +CC1CN(C(=O)c2cc3n(n2)CCCO3)CC(C)O1 +CC(C)c1cc(C(=O)N2CCCC(OCc3cccnc3)C2)n(C)n1 +COc1ccc(NC(=O)c2ccc(F)cc2)cc1O +COCCOC1CCN(c2ncc(C)cn2)C1Cc1ccncc1 +CC(CNC(=O)c1c[nH]c2ccccc2c1=O)N1CCc2ccccc21 +CCN(Cc1cccs1)C(=O)c1ccc2c(c1)OCCO2 +CCc1ccc(C(C)C(=O)NCc2csc(=O)[nH]2)cc1 +Cc1ccc(NC(=O)c2cnccn2)cc1S(=O)(=O)NC1CC1 +Cc1cccc(OCCCn2nnc(CCO)c2C)c1 +COc1ccc(C(=O)OCC(=O)Nc2ccc(F)cc2F)cc1F +COc1ccc(NC(=O)C(C)Sc2nncc3ccccc23)cc1 +O=C(CSc1ccc2c(c1)OCCCO2)N1CCCC1 +Cc1cc2c(cc1F)C(c1c[nH]c(=O)c(Cl)c1)NCC2 +Cc1cc(N)nc(SCCC(=O)Nc2ccccc2Cl)n1 +Cc1cc(Cl)c(NC(=O)NCc2cnn(C)c2C)cc1Cl +COc1ccc(CN(C)S(=O)(=O)c2ccc3c(c2)OCCO3)cc1 +Cc1ccccc1C1CC(C)N(C(=O)c2c(C)c(C)nn(C)c2=O)C1 +CCN(C(=O)CCc1cc(N)c(OC)c(OC)c1)C(C)(C)C +O=C(Cn1nc(C(F)F)cc1C(F)F)NCC1CCCO1 +Cc1cc(-c2c[nH]nc2C2CCCN2C(=O)C2CCCCC2)on1 +Cc1nnc(COc2ccc(NC(=O)CCc3cccnc3)cc2)o1 +Cc1ccc(NC(=O)COc2nncc3ccccc23)cc1 +CC(=O)N1CCCC1C(=O)Nc1ccc2nc(C)sc2c1 +O=C(NC1CCOCC1)c1c[nH]nc1C1CCCCC1 +O=C(NCc1c(F)cccc1F)c1ccc(N2CCCCC2)nn1 +CCOC(=O)CN(CC)S(=O)(=O)c1ccc(Cl)cc1C +O=C(Nc1cnc2n1CCCC2)c1ccn2nnnc2c1 +N#CCc1nc2cc(N)ccc2n1Cc1ccccc1C#N +CC(C)C(C)(C#N)NC(=O)Cn1nc(-n2cncn2)ccc1=O +CC(C)C(C#N)NC(=O)CNC(=O)c1c[nH]c2ccccc2c1=O +Cc1ccc(C(=O)N(Cc2ccncc2)C2CC2)c(=O)[nH]1 +CCS(=O)(=O)NCCCN(C)c1ccccc1F +COc1cccc(-c2cc(-c3nc4c5cnn(C)c5ncn4n3)n[nH]2)c1 +Cn1c(C(C#N)C(=O)Cc2cccc3ccccc23)nc2ccccc21 +Cc1noc(C2CCCN2S(=O)(=O)c2c(F)cccc2F)n1 +CCn1cc(C(=O)Nc2sc3c(c2C(=O)NC2CC2)CCC3)cn1 +COc1cc(Br)cc(NC(=O)NC2C=CC(CO)C2)c1 +CC(CCOc1ccccc1)C(=O)NC1CCN(c2cnn(C)c2)C1 +CCOCc1ccc(NC(=O)Nc2cnccc2C)cc1 +CN(CC(=O)NC1CC1)C(=O)CN1CCn2c(nn(C)c2=O)C1 +CCNC(=O)c1onc(-c2ccc(Br)cc2)c1N +Cc1ccc(NC(=O)c2cccs2)cc1NC(=O)c1cccnc1 +Cc1ccccc1OCC#CCNC(=O)C1CC(=O)N(C)C1 +O=C(CC1CCCO1)NCC(=O)Nc1ccccc1 +CC1CN(CC(O)c2ccc(C#N)cc2)CC(C)O1 +CC(OC(=O)CN(C)C(=O)c1ccccc1)c1cc(F)ccc1F +Cc1cnc(N2CC(N(C)Cc3ccco3)C3OCCCC32)nc1 +CNC(=O)CSc1nnnn1-c1ccc(Br)cc1 +O=C(NCC1(c2ccccc2)CC1)c1occc1CN1CCOCC1 +Cc1ccc(S(=O)(=O)N2C3CCC2COC3)cc1C +Cc1ccc2[nH]c(CSc3nnc(C)s3)cc(=O)c2c1 +CCOC(=O)CN(CC)C(=O)c1ccc(F)c(N)c1 +COc1c(F)cc(NC(=O)Cc2ccc(F)cc2F)cc1F +CCOC(=O)C(O)(c1ccc(NC(=O)NC)cc1)C(F)(F)F +O=S1(=O)N=C(NCc2ccco2)Nc2ccccc21 +CC(C)Cc1nc(CN(C)C(=O)c2cnnn2-c2ccccc2)no1 +COCC1CCCN(C(=O)c2ccc(-c3ccccc3)cc2)C1 +CSc1ncn(-c2nc(NC(C)C)nc(N(C)C)n2)n1 +O=C(NCC1CCC1)c1ncoc1C1CCCO1 +O=C(OCCCc1cccnc1)c1cnn(-c2ccc(F)cc2)n1 +CC(C)(C)OC(=O)N1CCCC(NC(=O)NC2C=CCCC2)C1 +COc1ccc(-c2cc(C(F)(F)F)nc(N)n2)c(OC)c1 +O=c1c(Cl)c(NCc2ccco2)cnn1-c1ccc(F)cc1F +COc1ccc(N2CCCN=C2NC(=O)c2cccc(OC)c2)cc1 +Cc1cc(C)n(-c2ccc(C(=O)N3CCCC3)cc2F)n1 +Cc1ccccc1C(=O)NC1CCN(C(=O)c2ccccc2O)CC1 +CNC(=O)CNC(=O)c1ccc(OC)c(OC)c1 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1cc(C(F)(F)F)c[nH]c1=O +Cc1nn(Cc2ccccc2Cl)c(C)c1C(=O)N1CCC1 +Cc1ccc(C(C)NC(=O)c2ccc(F)cc2Cl)o1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)N1CCc2ccccc2C1 +CC(C)CNC(=O)N1CCCC(C(=O)Nc2ccc(F)c(C#N)c2)C1 +CCNC(=O)CNC(=O)CCc1nnc(-c2ccc(C)cc2)o1 +Cc1ccc(OCC(=O)Nc2ccc(N)cc2O)cc1C +CC(=O)Nc1ccc(CC(=O)OCCc2c(C)n[nH]c2C)cc1 +CC(Oc1cccc(F)c1)C(=O)NCCc1ccccc1 +CC(C)(CO)NC(=O)Nc1cc(Cl)ccc1OCC(F)(F)F +CCCc1cc(=O)[nH]c(SCC(=O)c2ccc3c(c2)OCCO3)n1 +CC(C)OCCCNC(=O)C1CC(=O)N(c2ccccc2)C1 +Cn1ncc(C(=O)Nc2cc(Cl)ccc2Cl)c1N +COc1ccccc1CNC(=O)C(c1ccccc1)n1cnnn1 +Cc1ccccc1NC(=O)COC(=O)c1cccnc1 +CCC(=O)NCC(=O)Nc1cc(-c2cc(Cl)ccc2OC)n[nH]1 +COCc1cccc(NC(=O)c2cccc(OC)c2F)c1 +Fc1cccc(-n2nc(C3CCOC3)nc2-c2ccnnc2)c1 +CC(C)Nc1ncc(-c2c(C#N)c(N)nc3c2CCCC3)cn1 +O=C(C1CCCCC1)N1CCCC1CS(=O)(=O)c1ccccc1 +CCc1ccccc1NC(=O)CN1CCCCCC1=O +Cc1csc(CCC(=O)c2ccccc2Cl)n1 +CCN(CC)C(=O)CCC(=O)N1CCCC(C(C)(C)C)CC1 +CCOc1cc(CNC(=O)NC(C)C)ccc1OC(F)F +O=C(CSc1nn2cnnc2o1)c1ccc(Cl)cc1 +CCC(NS(N)(=O)=O)C(C)(C)c1ccccc1 +COc1ccc(CNC(=O)NCc2cnc(C)s2)cc1 +Cc1ccc(CNc2ncc(Br)cc2C#N)cc1 +CC1CCC(CO)(NC(=O)Cn2cncn2)CC1 +COC(=O)c1ccc(NC(=O)Nc2ccccc2OC)cc1 +N#Cc1csc(CNc2cnn(CC(F)(F)F)c2)c1 +CC(=O)c1cnc(-c2ccc(Br)cc2)[nH]1 +O=C(Nc1nnc(Cc2ccc(F)cc2)o1)C1CCCO1 +O=C(OCC(=O)N1CCc2ccccc21)c1ccc(-n2cccn2)cc1 +CCC(NC(=O)N1CCOCC1)c1ccccc1OC(F)F +CCN1CCN(C(=O)c2cc(C)nc3ccccc23)CC1 +CC(C)S(=O)(=O)NC1CCOc2ccccc21 +CCc1cc(-c2nnc(SCC(N)=O)n2C)cs1 +CCc1cc(C(=O)NCCCNS(C)(=O)=O)sc1C +CC(C)CNC(=O)COc1ncnc2sc3c(c12)CCC3 +O=C(NCc1ccccn1)C1(c2ccc(F)cc2)CCCC1 +CCC(C)NC(=O)Nc1cc(F)c(OC)cc1OC +CCn1nnc2c(=O)n(Cc3cccc4ccccc34)cnc21 +CN(C(=O)Cn1ccnc1-c1cnccn1)C1CC1 +O=C(NCc1ccccc1)C1CCN(C(=O)c2ccccc2)CC1 +COC(=O)CCCOc1ccc(C#N)cc1Cl +CN(C)C(=O)c1ccc(CNC(=O)Nc2cccc(Cl)c2F)cc1 +CC(=O)N(C)Cc1cccc(NC(=O)c2ccc(N(C)C)cc2)c1 +O=C(Nc1ccc(F)cc1)c1c[nH]c2ccc(F)cc2c1=O +COc1ccc(C(=O)NCC2CCC(c3ccccc3)CC2)nn1 +COCc1c(C(=O)Nc2ncc(C)s2)sc2cccc(F)c12 +Cc1ccc2ncc(C(=O)N(Cc3ccccc3)CC3CCCO3)n2c1 +CC1CC1CNS(=O)(=O)c1ccc2c(c1)oc(=O)n2C +O=C(Cn1ccccc1=O)NCc1nnc2n1CCCCC2 +CCCCC(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 +CN(CCN(C)c1ccccc1)C(=O)Cc1c(F)cccc1F +CCOc1cc(Cl)ccc1NC(=O)NCc1cnn(C)c1C +Nc1cc(CCOc2cc(Cl)cc(Cl)c2)no1 +CS(=O)(=O)N(CC(=O)NCc1ccncc1)c1ccc(F)cc1 +CCOCC1CCCN(C(=O)c2c[nH]nc2-c2ccccc2)C1 +COC(=O)c1cnn(-c2ccc(S(N)(=O)=O)cc2)c1N +COc1ccc(C(C)n2c(=O)[nH]c3ccc(Cl)cc3c2=O)cc1 +Cn1cnc2c1C(C(=O)NC1CC1)N(S(C)(=O)=O)CC2 +CCCOc1cc(OC)ccc1CNc1ccon1 +COc1ccc(F)cc1NC(=O)COc1ccccc1O +CCn1cc(-c2cc(=O)n3nc(-c4cccc(C)c4)c(C)c3[nH]2)c(C)n1 +CC(NC(=O)C1(c2cccc(F)c2)CCC1)c1nc2ccccc2[nH]1 +O=C(NCCCN1CCCC1=O)NCc1nc2ccccc2s1 +O=C(CSc1ccc(Cl)cc1)Nc1nnc(-c2ccccn2)o1 +Cc1cc(C)n(CC2CN(Cc3ccccn3)CCO2)n1 +CCCn1nc(-c2ccc(OC)c(C(C)C)c2)cc(N)c1=O +COc1ccc2c(c1)C(NC(C)=O)C(=O)N2Cc1ccccc1 +Cc1cccn2c(=O)c(C(=O)NCc3ccccc3)cnc12 +Cc1ccc(NC(=O)N2CCC(N3CCOC(C)C3)CC2)cc1C +Cc1ccc(C(=O)NCCNc2ccc(C#N)cn2)cn1 +CCCC(C)NC(=O)CCCn1cnc2c1c(=O)n(C)c(=O)n2C +C=CCNC(=O)c1ccc(NC(=O)C2CC2c2ccccc2)cc1 +Cc1ccc(C(=O)NCC(O)c2ccc(F)cc2F)s1 +COc1ccc(C2(C(=O)NCCC(C)(C)C)CCOCC2)cc1 +CCn1nc(C)cc1-c1nnc(CCC(=O)NC2CCCCC2)o1 +CS(=O)(=O)NCCNC(=O)CCc1ccsc1 +CSc1ccc(C(=O)NC(C)c2cccc(N3CCCC3)c2)cn1 +Cc1nn(Cc2cccs2)c(N)c1Br +Cc1nc(C(C)(C)NC(=O)NCCOc2ccccc2)sc1C +O=C(NCC1(c2ccccc2Cl)CC1)N1CCN2C(=O)NCC2C1 +CC(Cc1ccccc1F)NC(=O)NC(C)C(C)C +O=C(CCc1ccccn1)Nc1cccc(CSc2ccccn2)c1 +COCCC1(CNC(=O)c2scnc2C2CC2)CCCC1 +CNC(=O)c1ccc(NC(=O)c2cc(OC)cc(OC)c2)cc1Cl +CCN(Cc1ccccc1)C(=O)C1CC(=O)N(c2cccc(C)c2)C1 +CC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)c2cc(C)no2)c1C +CCc1cc(=O)oc2c3c(ccc12)OCN(Cc1cccnc1)C3 +CCCn1cnc2c1c(=O)n(CC)c(=O)n2-c1ccc(C)cc1 +O=C(Nc1ccccc1N1CCCC1)C1CCCC1 +CCC(C)(C)NC(=O)c1ccc(NC(=O)NCc2cccn2C)cc1 +CCN(CC)C(=O)CCC(=O)Nc1cc(C)c(Br)cn1 +CCOC(=O)NCCC(=O)N(C)Cc1c(C)nc2sc(C)cn12 +CC(NC(=O)Cc1ccc2c(c1)CCC2)c1nc2ccccc2[nH]1 +N#CCCN(Cc1ccco1)S(=O)(=O)c1ccc(Cl)cc1F +CC(C)CC(C)NC(=O)C1CCCN(C(=O)c2cccs2)C1 +COc1ccc(Cl)cc1-n1nc(CO)cc1C +CC(=O)Nc1ccc(Oc2cc(C(F)(F)F)cnc2N)cc1 +CCCC1CN(C(=O)c2c[nH]nc2-c2cccc(Cl)c2)CCO1 +O=C1NC(c2ccc(-n3ccnc3)c(F)c2)Nc2ccccc21 +COc1cc(NC(=O)c2cc3n(n2)CCCO3)cc(OC)c1OC +CC(=O)c1ccc(C#CCNC(=O)Cc2ccccc2)cc1 +COc1ccc(-n2ncnc2Cc2cc(C)no2)cc1 +CCOc1ccc(OCC)c(NC(=O)c2[nH]c(C)c(C(C)=O)c2C)c1 +CC(C)c1nnc(NCc2cccc3cn[nH]c23)o1 +CCCn1c(C)nnc1SCc1nc2ccccc2[nH]1 +NC(=O)CSc1nnc(-c2ccc(Br)cc2)o1 +O=C(CSc1ccccc1)Nc1nnc(Cc2cccs2)o1 +N#CC(NCCc1ccc(Cl)cc1)c1ccco1 +Cc1ccc(NC(=O)CSc2nncn2Cc2ccco2)cc1C +Cc1noc(C)c1CC(=O)N1CCC(Cc2ccc(F)cc2)CC1 +O=C(c1ccc(S(=O)(=O)Nc2cccnc2)o1)N1CCCC1 +CC(=O)Nc1ccc(C(=O)NCC(C(C)C)N2CCOCC2)cc1 +C=CCOC(=O)C1CC(=O)N(CCc2ccccc2)C1 +Cc1cccc(NC(=O)N2CCc3c(F)cc(F)cc3C2)n1 +CC(C)NC(=O)Cn1ncc2ccsc2c1=O +CS(=O)(=O)c1cc(C(F)(F)F)cc(C(F)(F)F)c1 +COc1nn(C)cc1C(=O)NCC1(c2cccs2)CC1 +COc1ccc(C)c(NC(=O)N2CCN(Cc3ccccn3)CC2)c1 +CCOc1ccc(OC(=O)CCc2c(C)nc3ncnn3c2C)cc1 +OCCN1CCN(c2nc(-c3ccccc3)nc3ccccc23)CC1 +O=S(=O)(NCc1ncc(-c2ccccc2)o1)c1ccccc1 +CNC(=O)c1ccc(NC(=O)NCc2nnc3ccccn23)cc1 +COC(=O)c1ccc(Cn2c(C)nc3cc(N)ccc32)cc1 +Cc1ccnc(NC(=O)c2ccc(OCc3noc(C)n3)cc2)c1 +O=C(Nc1cccc(Cl)c1)c1cccc(-n2cnnc2)n1 +Cc1cc(C(C)NC(=O)C2(C)CC2(Cl)Cl)c(C)s1 +CCOC(=O)CCCOc1ccc2oc(=O)cc(C)c2c1 +CC(c1ccccc1)N(C)C(=O)c1ccccc1N +CC(=O)N1CCC(c2cncc(-c3cnn(C)c3)n2)CC1 +CCOC(=O)CNc1nc2cc(-c3nccs3)ccc2[nH]1 +CCc1cc(NC(=O)C2CC(=O)N(c3cc(Cl)ccc3C)C2)[nH]n1 +COc1ncccc1NC(=O)N1CCN(c2ccccc2)CC1 +Cc1cc(C)cc(NC(=O)c2nc3ccc(O)cc3n2C)c1 +CS(=O)(=O)c1ccc(C(=O)NCc2ccccc2F)cc1 +O=C(NCc1ccccc1F)Nc1cccc(-c2nnco2)c1 +Cn1c(SCc2ccccn2)nc2sc3c(c2c1=O)CCC3 +COc1ncncc1NC(=O)NCc1cnn(C)c1C +COCc1nc2ncc3c(=O)n(-c4ccc(C)cc4)ccc3n2n1 +CCCc1nnc(NC(=O)NC2(c3ccccc3F)CC2)s1 +NC(=O)c1ccsc1NC(=O)c1ccc(N2CCCC2=O)cc1 +CC1CC(C)CN(C(=O)CSc2nnc(-c3ccco3)o2)C1 +O=C(Nc1nnc(C2CC2)s1)c1cn2cccnc2n1 +Cc1cc(C)cc(C(C)NC(=O)NCc2cnn(C)c2)c1 +Cc1nc(CNC(=O)c2ccc3c(c2)NC(=O)CS3)c(C)s1 +CCn1c(C)ccc(-c2csc(NCC(C)C)n2)c1=O +CCOc1ccc(C(=O)COc2ccc(NC(C)=O)cc2)cc1 +CCc1nnc2n1CCN(C(=O)C1CCCc3ccccc31)C2 +O=C(CC1CCCO1)NC(c1cccs1)C1CCCC1 +N#CCC(=O)Nc1ncc(Cc2ccccc2Cl)s1 +O=C(Nc1cccc(N2CCCCC2=O)c1)Nc1ccccc1F +CCn1ccc(NC(=O)CCn2ncc3ccc(Cl)cc32)n1 +CC1CCCC1NC(=O)C(NC(=O)c1ccccc1)c1ccccc1 +CC(C)(C)NC(=O)C1CC(=O)N(c2ccccc2Cl)C1 +Cn1cc(C(=O)N2CCOCC2)cc(NC(=O)c2ccccc2)c1=O +CCCNc1ccccc1S(=O)(=O)N1CCOCC1 +Cn1ccc(CNc2cnn(CC(F)(F)F)c2)c1 +CCc1nc(-c2cc(NC(=O)c3ccccn3)c(C)s2)no1 +Cc1c(C(=O)NCc2cccc(F)c2)nc2cc(Cl)ccn12 +CCOc1ccc(-c2nnc3n(C)c4c(=O)[nH]c(=O)n(C)c4n23)cc1 +CC(=O)NC(C)C(=O)NC(C)c1ccc(S(C)(=O)=O)cc1 +CCNC(=O)CNC(=O)NCCNC(=O)c1ccc(F)cc1 +CCc1ncc(C(=O)N2CCN(c3ccccc3OC)CC2)s1 +CN(CC(N)=O)C(=O)c1cc(Br)ccc1O +COc1cc(-c2nc3cc(N)ccc3[nH]2)ccc1OCC(C)C +COc1cc(C#N)ccc1OCC(=O)N(C)C1CC1 +Cc1cccc(S(=O)(=O)N2CCCc3cc(O)ccc32)c1 +Cc1ccc(F)c(-n2nnnc2Cn2cc(Br)cn2)c1 +CCCOc1ccc(Br)cc1CN1CCNC(=O)CC1 +Cc1nnc(N2CCCC(C(=O)NC3CCCCC3)C2)c(C#N)c1C +Cc1nnc(-c2cc(NC(=O)c3sccc3C)c(C)s2)o1 +Cc1noc(CSc2ccccc2C(=O)NCc2ccccn2)n1 +Cc1ccc2ncc(C(=O)N3CC(C)Oc4cc(F)ccc43)n2c1 +CCc1cc(NC(=O)c2cc(NC(C)=O)ccc2O)[nH]n1 +CCNC(=O)CN1CCN(C(=O)Cn2ccc(=O)[nH]c2=O)CC1 +CC1(C)CCC(CNC(=O)C2CCN(C(=O)N3CCCC3)CC2)CC1 +COC1(C)CC(NC(=O)Nc2cnn(C)c2)C1(C)C +O=C(NCc1ccon1)c1cccc(-c2ncc[nH]2)c1 +CCn1nccc1C(=O)Nc1nnc(-c2csc(C)n2)o1 +CCCOC(=O)c1ccc(NC(=O)COC)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)C1Cc2cccc(F)c2O1 +Cc1cc(NC(=O)NC(C)c2ccccc2F)no1 +COc1ccccc1CNC(=O)COc1ccc(C)cc1 +CC(C)N(C)C(=O)CCn1c(=O)oc2ccccc21 +CCCOC(=O)c1ccc(NC(=O)c2cc(C)nn2C)cc1 +Cc1nc(CC(=O)Nc2ccc(CS(N)(=O)=O)cc2)cs1 +O=C(NCC1(O)CCCc2ccccc21)c1cc(F)ccc1F +CCOCC(=O)N(Cc1ccco1)Cc1cccs1 +Cc1ncc(C(=O)N(C)Cc2ccc(Oc3ccccc3)cc2)s1 +COc1cccc(CNC(=O)c2ccc(F)c(S(N)(=O)=O)c2)c1 +CC(Oc1ccccc1F)C(=O)NCc1ccncc1 +Cc1cccc(-c2nnc(COC(=O)c3ccc(C)nc3)o2)c1 +CC(=O)c1cccc(COC(=O)c2cc(-n3cccn3)ccn2)c1 +CNC(=O)c1cc(C)ccc1NC(=O)C(C)Sc1ccccc1 +COC(=O)c1ccc(NC(=O)COc2cccc3cccnc23)cc1 +NC(=O)OCCNC(=O)Cc1csc2ccc(Cl)cc12 +COCc1nn2c3c(cnc2c1-c1ccc(Cl)cc1)C(=O)CCC3 +Cc1ccc(O)c(C(=O)N2CCN(C(=O)N3CCCCC3)CC2)c1 +CCOC(=O)c1cc(NC(=O)Cc2noc3ccccc23)c[nH]1 +Cc1nc(-n2c(C)ccc2C)sc1C(=O)NC(C)C +FC(F)(F)Oc1cccc2c1CCNC2c1ncccn1 +Cc1ccc(OC2CCN(C(=O)c3ccccn3)CC2)nn1 +COC(=O)c1cc(-c2ccc3c(c2)CCCC3)[nH]c1N +CCCN(Cc1ccsc1)C(=O)c1ccc2c(c1)OCO2 +O=C(c1cccnc1-c1ccc2c(c1)OCCO2)N1CCCC1 +CCOC(=O)N1CCC(NC(=O)NCCCC2CCCC2)CC1 +CCSc1ccc(NC(=O)c2cccc(F)c2)cn1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)c1c[nH]c2cccc(F)c12 +COCCN1CCN(C(=O)c2ccn3ccnc3c2)CC1=O +CCC(CC)C(CNC(=O)N1CCC(CO)CC1)N1CCOCC1 +CC1CN(C(=O)NCc2ccsc2)CC(C)O1 +Cc1cc(O)ccc1NC(=O)CCc1cccnc1 +COCC1(CNc2cc(C(C)C)nc(N)n2)CC1 +CCOC(=O)CCCNC(=O)Nc1cccc(Cl)c1Cl +CC(OC(=O)Cc1c[nH]c2ccccc12)C(=O)N1CCCCC1 +COc1ccc(OC)c(C(=O)C2CCCN2C(=O)C(C)C)c1 +Cn1cnc(CNC(=O)C(C)(C)C2CCCC2)n1 +OCC(O)CSc1nnc(-c2ccccc2)n1Cc1ccco1 +CCNC(=O)c1cn(-c2ccc(F)cc2)nc1-c1cccc(OC)c1 +Cc1ccc(CNC(=O)Nc2ccc(OCC(N)=O)cc2)c(C)c1 +COc1cc2cc(C)c(SCCN3CCOCC3)nc2cc1OC +CCCc1nnc(NC(=O)CNC(=O)c2ccc(OC)cc2)s1 +CC(C)CCn1nc(-c2ccccc2Cl)cc(N)c1=O +COCc1ccc(C(=O)Nc2cc(C)nc3c(OC)cccc23)o1 +CC(NS(=O)(=O)c1cccs1)c1cccc(OC(F)F)c1 +CCNC(=O)CCN1CCOC(c2ccc3cc(OC)ccc3c2)C1 +c1ccc(-c2nccn2-c2ccc3cc[nH]c3c2)nc1 +CCN1C(=O)C(C)Oc2ccc(S(N)(=O)=O)cc21 +CC(C)N(C)S(=O)(=O)NCC1CCCc2ccccc21 +CCc1onc(C)c1NC(=O)NC(C)c1cn(-c2ccccc2)nn1 +CCS(=O)(=O)N(C)C(C#N)c1ccccc1OC +O=C(Nc1ccc(NC(=O)C2CCCO2)cc1)c1ccsc1 +c1ccc(C(NCc2nnnn2-c2ccccc2)c2cccs2)cc1 +O=C(CCNC(=O)c1n[nH]c2c1CCC2)NC1CCCC1 +O=C(CCOc1ccccc1)c1cccc(C2OCCCO2)c1 +Cc1snc(S(=O)(=O)Cc2ccc(Cl)cc2)c1C#N +NC(=O)c1cccc(CC2CCN(C(=O)C3CCC(O)CC3)C2)c1 +N#Cc1ccc(-n2c(N)nc3ccc(F)c(F)c32)nc1 +CC(C)C1C=CCN1C(=O)Nc1cccc(C#N)c1 +CCn1ncc(-c2ccc(Br)cc2)c(N)c1=O +Cc1ccc(C(=O)NCCNC(=O)N2Cc3ccccc3C2)cc1 +CN(C)c1nc(N2CCc3ccccc32)ncc1F +O=C(c1ccncc1)c1nnc(-c2ccc(Cl)cc2)o1 +COc1ccc(C(=O)N2CCc3ccccc3C2)cc1N +O=c1cc(CN2CCCC(O)CC2)[nH]c2c(Cl)cccc12 +O=S(=O)(NCc1cnn(Cc2ccccc2)c1)N1CCCCC1 +Cc1ncsc1C(=O)N1CCN(C(C)c2ccccc2F)CC1 +Cc1cc(C)n2nc(NC(=O)C3CCCCC3)nc2n1 +CC(=O)N(C)c1ccc(NCC(=O)Nc2ccc(C)c(C)c2)cc1 +Cc1ccc(CC(=O)Nc2c(C)nc3sccn3c2=O)cc1 +CCNC(=O)c1cccc(NC(=O)c2ccc(OCC(F)F)nc2)c1 +COC(=O)c1ccc(NC(=O)COc2ccccc2)cn1 +Cc1ccc(-c2c(CO)nnn2-c2ccc(C)cc2)cc1 +CCc1noc(CN(C)C(=O)c2cnn(CC)c2)n1 +CC(C)(CNC(=O)Cc1cccc(F)c1F)NC(=O)OC(C)(C)C +O=C(CCn1ccccc1=O)OCc1ccccc1F +O=C(c1ccccc1Cl)n1oc2ccccc2c1=O +CCNC(=O)c1cc(NC(=O)C2CC2)n(-c2ccccc2)n1 +Cc1cccc(-n2ncc(C(=O)NC3CCCCNC3=O)c2C)c1 +O=C(Cc1ccccc1)N1CCN(c2ccc(-n3cccc3)nn2)CC1 +COc1cc2nc3n(c(=O)c2cc1OC)CCN(C(C)=O)CC3 +CC1CCCCC1OCCSc1ncnc2c1cnn2C +FC(F)(F)Cn1cc(NCC=Cc2ccco2)cn1 +CCC(C)n1nccc1NS(=O)(=O)c1cccc2nonc12 +CN(C)C(C(=O)N(Cc1cccc(O)c1)C1CC1)c1ccccc1F +COCCn1nc(-c2cccs2)cc(CC#N)c1=O +COC(=O)C1CCCN(S(=O)(=O)c2cccs2)C1 +CCOC(=O)CC(C)CNC(=O)c1cc(C)oc1C +Cc1cc(-c2cncnc2-c2ccc(CNC(=O)C3CC3C)cc2)on1 +CC(C)C(NC(=O)c1ccn2ccsc12)C(=O)NC1CC1 +O=C(COc1ccc(Cl)cc1)N(CC1CCCO1)c1ccncc1 +CCOc1ncccc1C(=O)Nc1cccc(Cl)c1 +CC(=O)Nc1ccc(CC(=O)Nc2nc(C)no2)cc1 +COc1cc(N(CC(N)=O)S(C)(=O)=O)c(OC)cc1Cl +Cn1ccc(NC(=O)CCC(=O)c2ccc(Br)cc2)n1 +CC(C)Sc1nnc(CN2CCCC2=O)n1-c1ccccn1 +CCOc1cccc(CC(=O)NCC(C)(C)c2ccncc2)c1 +CC(=O)Nc1ccc(C)c(NC(=O)CSc2nc(C)cc(C)n2)c1 +Cc1cc(SCc2nc3ccccc3[nH]2)ncn1 +O=C(NCCc1nc(-c2cccs2)c[nH]1)c1ccccc1 +N#CCCNS(=O)(=O)c1ccc2c(c1)CCCC2 +CCc1ccccc1OCC(=O)NC1CCN(c2nnnn2C)CC1 +Cc1ccccc1C1CCCN(c2cc(N)ncn2)C1 +O=C(NCCOc1ccc(F)cc1F)c1ccc(F)nc1 +CC(C)C(NC(=O)NCc1ccccc1)C(=O)NCc1ccccn1 +COCC(O)CN(C)C(=O)Cc1cc(=O)[nH]c(=O)[nH]1 +Cc1cc(F)ccc1NC(=O)CCc1c(C)n[nH]c1C +COc1ccc(OC)c(C2CCCN2c2ccc(C#N)cn2)c1 +O=C(Nc1cc(F)ccc1F)c1cccc(Oc2ncccn2)c1 +O=C(Cc1cccnc1)NCCc1nc2ccccc2[nH]1 +COc1ccc(OCC(=O)NCCn2ncc3c2c(C)nn3C)cc1 +CN(CC1CC1)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CCN(CC)C(C#N)c1cc(Cl)c2c(c1)OCCO2 +COc1ccc(Cl)cc1NCCC(=O)OC1CC(C)OC1=O +O=C(CNC(=O)NCCOc1ccc(F)c(F)c1)NC1CC1 +Cc1ccccc1COc1ccc(CCC(O)CO)cc1 +Cc1ccc(C(=O)NCCc2nnc(SCC(C)C)n2C)s1 +Cc1cc(C)c(NC2=NS(=O)(=O)c3ccccc32)c(Cl)c1 +O=C(Nc1nc(COc2ccccc2)cs1)C1CCC1 +Cc1cc(C)c2c(c1)c(C)cc(=O)n2CC(=O)Nc1nc(C)cs1 +O=C(Nc1ccc(Oc2ccc(F)cc2)nc1)c1ccoc1 +CNC(=O)c1cn[nH]c1C1CCCN1C(=O)c1coc(C)n1 +CC(C)c1ccc(C(=O)Nc2ccccc2C(N)=O)cc1 +CCCC(=O)N1CCCC1C(=O)NC(C)CCc1ccccc1 +CCc1cccc(NC(=O)CNS(=O)(=O)N(C)C(C)C)c1 +FC(F)(F)c1ccccc1CNCc1ccccn1 +O=S(=O)(NCc1ccccc1)N1Cc2ccccc2C1 +COc1ccc(C(=O)N2CCCC(O)C2)c(O)c1 +CN(C)S(=O)(=O)c1ccc(SCC2CC2(Cl)Cl)nc1 +COC(=O)c1ccc(C(=O)NC2CCN(c3nccs3)CC2)cc1 +C#CCN1CCC(C(=O)NCCNC(=O)Cc2cccc(F)c2)CC1 +CNc1snc(C)c1C(=O)N1CCN(Cc2cccnc2)CC1 +CCn1ccc(NC(=O)c2cc3ccccn3n2)n1 +N#Cc1ccccc1Cn1ncc(N2CCCCC2)cc1=O +COc1ccc(CN2CC(C(=O)Nc3cc[nH]n3)CC2=O)cc1 +COC(=O)c1cc(OC)ccc1NC(=O)CCn1cc(C)cn1 +CC(=O)NC(C(=O)Nc1ccc(C)c(Cl)c1)C(C)C +CC(=O)Nc1ccc(F)c(NC(=O)NCC(C)(C)c2ccncc2)c1 +CC(=O)NC(C)C(=O)OCCCC1CCCCC1 +OCc1nnn(Cc2cccc(F)c2)c1C1CCCO1 +CC1(C)CN(C(=O)c2cccnc2OCC(F)F)C1(C)C +CC(C)N(C(=O)c1cc(F)ccc1Br)C1CCC1 +COC(=O)CC1C(=O)NCCN1C(=O)c1c(F)cccc1F +Cc1occc1C(=O)Nc1ccccc1S(=O)(=O)N1CCCC1 +CC(=O)Nc1ccc(CC(=O)NCCc2ccc(F)cc2C)cc1 +OCCc1ccccc1NCc1ccc(F)c(F)c1 +O=C(NCCCOCC1CCCO1)NC1c2ccccc2CC1O +Cc1nc2ncccc2c(=O)n1CCNC(=O)c1ccccc1 +CN(Cc1cccnc1)C(=O)C1CCCN1C(=O)Cc1cccs1 +O=C(COC(=O)c1ccc2ccccc2n1)Nc1ccc(F)c(F)c1 +O=C(Cn1ccnc1)N1CC=C(c2ccccc2Cl)CC1 +Cc1ccc(OCC2CCCN(C(=O)c3snnc3C)C2)cc1 +CC(NS(=O)(=O)N1CCOCC1)c1ccncc1 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+Fc1cc2ncnc(Sc3nnc(-c4cccs4)o3)c2cc1F +COc1cccc(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)c1 +CCOC(=O)N1CCC(NC(=O)Nc2ccccc2OC)CC1 +Cc1cnc(C(=O)N2CCCC3(CCN(CC4CC4)C3=O)C2)cn1 +CS(=O)(=O)N1CCOC2CC(COCc3ccccn3)CC21 +O=C(NCc1ccncc1)c1cccc(NC(=O)c2ccccc2)c1 +O=C(COc1cccc2c1CCC2=O)NCCOc1ccccc1 +CC(C)Cc1nnc(NC(=O)c2cccnc2N2CCCC2)s1 +COC(=O)Nc1cc(NC(=O)c2ccc(Cl)cc2F)ccc1F +COc1ccc(N)cc1NC(=O)c1ccc(OC)c(OC)c1 +CC1CN(C(=O)c2ccccc2C(=O)c2cccs2)CC(C)O1 +COC(=O)C(NC(=O)Cc1cc(C)[nH]n1)c1ccc(Cl)c(F)c1 +Brc1ccc(Cc2nccn2Cc2cccnc2)cc1 +COc1ccc2nc(SCc3ncon3)[nH]c2c1 +CC1CN(S(=O)(=O)CCNC(=O)NCC2CCCC2)CC(C)O1 +NC(=O)CNC(=O)c1cccc(Oc2ccc(Cl)cc2)c1 +CCOc1ccc(NC(=O)c2cnn3ccccc23)cc1 +Cc1cccc(NC(=O)CCSc2nc3nc(C)ccc3o2)c1 +COC(=O)C(NC(=O)c1ccc(NC(=O)C2CC2)cc1)C(C)C +COC(=O)c1cccc(C(=O)NC(C)C2CCCO2)c1 +COc1ccc(OC(=O)CCn2cnc3sccc3c2=O)cc1 +O=S(=O)(Cc1ccccc1)NCC1Cn2nncc2CO1 +Cc1cccc(CC(=O)NCCNC(=O)c2cccc(C)c2)c1 +CC(C)(CNC(=O)NC(CO)c1ccco1)c1ccncc1 +Cc1cc(F)ccc1C(=O)NCC(O)c1cccc(OC(F)F)c1 +CCNS(=O)(=O)c1ccc(O)c(C(=O)OC)c1 +N#Cc1ccnc(N2CCN(C(=O)n3ccnc3)CC2)c1 +Cc1nccn1-c1ccc(C(C)NC(=O)c2ccc3[nH]cnc3c2)cc1 +CNC(=O)c1ccc(C)c(NCc2cccn2C)c1 +Cc1cc(NC(=O)N2CCN(CC=Cc3ccccc3)CC2)no1 +Cn1c(CNc2nccnc2C#N)nnc1C1CCC1 +CCC(C)n1ncc(C(=O)N(C)c2ccc3c(c2)CCO3)c1C1CC1 +Cc1cccc(NC(=O)N2CCN(Cc3cccs3)CC2)c1 +CC(OC(=O)c1ccco1)C(=O)N(c1nccs1)C1CCCCC1 +CC(C)(NC(=O)NCCNC(=O)C1CC1)c1ccc(F)cc1Cl +Cc1ccc(-c2csc3ncn(CCc4ccncc4)c(=O)c23)cc1 +CNC(=O)COC(=O)c1ccc(OCC(F)F)nc1 +CCOc1ccc(S(=O)(=O)N=c2cc(C)cc[nH]2)cc1C +O=C(c1ccc(Br)cc1)N(CCO)C1CCCCC1 +Cc1ccccc1C(C)(C)CNC(=O)c1cscn1 +NC(=O)c1ccccc1NC(=O)CSc1ncnc2nc[nH]c12 +Fc1ccc(N2CCN(c3c4c(nc5nncn35)CCC4)CC2)cc1 +CC1Oc2ccc(NC(=O)NCc3cccc(Cl)c3)cc2NC1=O +CC(c1ccccc1Cl)N(C)C(=O)c1ccc(S(N)(=O)=O)o1 +Cn1nnc2c(N3CC(C(=O)NCC4CCCCC4)C3)ncnc21 +Cn1ccc(C(=O)N2CCc3sccc3C2)cc1=O +COc1cc(OC)cc(N2C(=O)CCC2(C)C(=O)NC2CCCC2)c1 +COc1cccc(NC(=O)CN(C)C(=O)c2ccc3nccn3c2)c1 +O=C(NC1CCCCNC1=O)c1cc2c(s1)-c1ccccc1OC2 +CC1Oc2c(cccc2C(=O)N2CC(=O)Nc3ccccc32)NC1=O +CCOc1ccc(C(O)CN2CCN(c3ccccc3)CC2)cc1 +Cc1ccc(C(C)NC(=O)C2CC(=O)N(CC(F)(F)F)C2)o1 +CCCC(C)C(=O)Nc1cc(C#CCO)ccc1C +COC(=O)c1cccc(NC(=O)C(C)OCC(F)(F)F)c1C +Cc1cccnc1C(Cc1ccsc1)NCc1cnn(C)c1 +COc1ccc(S(=O)(=O)Nc2cccnc2)cc1C(C)(C)C +CCN(C)C(=O)NCc1cn(-c2ccccc2)nn1 +O=C(Nc1ccc2c(c1)OCCO2)Nc1ccc2c(c1)OCCO2 +COc1ccc(NC(=O)Cn2c(CO)nc3ccccc32)c(OC)c1 +O=C(Nc1ccncc1)N(Cc1ccc(O)cc1)Cc1ccco1 +N#CC(C(=O)c1coc2ccccc12)c1nnc2n1CCCCC2 +CC(CNC(=O)c1cncn1-c1ccccc1)N1CCOCC1 +CC(=O)c1c[nH]c(C(=O)NCCc2ccc(C(C)C)cc2)c1 +CCCOc1cccc(NC(=O)CNC(=O)c2cc(F)cc(F)c2)c1 +CCCCN(CC)C(=O)CSc1nnc2cc(C)nc(C)n12 +Cc1cccc(Cn2nc(C3CCOC3)nc2-c2cnc(C)cn2)c1 +CCOCc1nc(-c2ccc(F)cc2Cl)n(C)n1 +Cc1ccnn1-c1ccc(Br)c(N)c1 +CCN(CC(O)c1ccc(OC)cc1OC)c1ccccc1 +Cc1ccccc1CNC(=O)c1cnc2sc3c(n2c1=O)CCC3 +O=C(NC(CO)c1ccccc1)c1cn(Cc2ccc(F)cc2)nn1 +COCCNC(=O)C1CCC(C)N(C(=O)c2cccc(N(C)C)c2)C1 +Cc1cc(-n2nc(CCc3ccccc3)nc2C2CC2)ccn1 +Cc1ccc2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)c(C)nc2c1 +COCCNC(=O)CSc1ccnc2c1c(=O)n(C)c(=O)n2C +COCCNS(=O)(=O)c1ccc2c(c1)n(C)c(=O)n2C +CCCCS(=O)(=O)NC(C)c1ccc(-n2ccnc2)cc1 +O=C(NCCNc1ccc2ccccc2n1)c1scnc1C1CC1 +CCCc1n[nH]c(C2CN(CCn3nc(C)cc3C)CCO2)n1 +CCOC(=O)COc1cc2occ(-c3cscn3)c(=O)c2cc1C +O=C(c1ccco1)N1CCN(C2=CS(=O)(=O)c3ccccc32)CC1 +O=C(NCC(=O)N1CCCCC1)Nc1ccc(Cl)cc1 +CS(=O)(=O)c1nccn1CCCc1ccccc1 +CN(CCCOc1cccc(C#N)c1)Cc1ncnn1C +CC(=O)c1cccc(NC(=O)COC(=O)c2cc(Cl)cn2C)c1 +COc1cc(CN2CCOC3(CCC3)C2)c(SC)cc1OC +Cc1ccc(C(C)NC(=O)CCc2ccccc2)o1 +Cc1cc(C)nc(C(C#N)C(=O)CNC(=O)Cc2cccc(F)c2)n1 +COC(=O)CCC(=O)NCc1ccc(F)c(Cl)c1 +NC(=O)C1CCCN(C(=O)c2ccc(O)c(Cl)c2)C1 +N#Cc1ccc(-c2coc(N)c2C(=O)c2ccccc2)cc1 +CC(NC(=O)c1c[nH]nc1-c1ccccc1Cl)c1ccncc1 +CCn1nc(C)c2c1cnn2CCNC(=O)c1cccs1 +CCN(CC1CC1)C(=O)Nc1ccc(C(=O)OC)cc1 +Cc1nnc(NC(=O)C2CNCc3ccccc32)s1 +Cc1sc(-c2ccno2)cc1S(=O)(=O)NCc1ccccn1 +Cc1ccccc1C1CCCN1c1ccc(C(N)=O)nn1 +COCCN1CC(C(=O)N2CCOCC2C2CC2)CC1=O +Cc1ccc(S(=O)(=O)N2CCNC(=O)C2)c2cccnc12 +O=C1CCC(C(=O)N2CCN(C(=O)Cc3ccc(Cl)cc3)CC2)N1 +COc1ccc(OC)c(-c2nnc(NC(=O)c3ccccc3)o2)c1 +Nc1ccccc1-c1nn2c(-c3ccco3)nnc2s1 +Cc1c(C(=O)Nc2cccc(C#Cc3ccccc3)c2)cnn1C +Cc1ccc(CN(C)S(=O)(=O)N(C)C(C)C)o1 +Cc1cc(=O)oc2cc(NC(=O)NCc3ccoc3)ccc12 +Cn1c(CNC(=O)CCNC(=O)c2ccccc2)cc(=O)n(C)c1=O +CCC(CC)CNC(=O)C(N)c1ccc(F)cc1N +O=C1CCC(C(=O)N2CCC(CO)(CCc3ccccc3)CC2)N1 +COc1cc(C#N)ccc1OCCn1nnc(-c2ccccc2)n1 +Cc1cc(C(=O)N(C)Cc2ccco2)nc(N(C)C)n1 +Cc1nn2c(=O)cc(CNc3cccc(Cl)c3)nc2s1 +O=C(NCc1cn2cc(Cl)ccc2n1)c1ccc2[nH]cnc2c1 +CCOC(=O)c1ccccc1NC(=O)c1nc2nccc(C)n2n1 +COCc1nc2sc(C)c(-c3ccc(C)cc3)c2c(=O)[nH]1 +CC(Nc1ccc(S(C)(=O)=O)cc1)c1ccccc1F +Cc1nc(Nc2ccccc2)cc(C2CCN2C(=O)CO)n1 +CS(=O)(=O)N1CCN(C(=O)CCc2ccc(F)c(F)c2)CC1 +CC1CCN(C(=O)c2onc(S(C)(=O)=O)c2N)CC1 +CCn1cc(NC(=O)CCc2cnn(C)c2)c(C(N)=O)n1 +CCc1c(C(=O)NCC2CCCO2)cnn1-c1ccccn1 +Cc1cc(NC(=O)CSc2ccncc2)ccc1C(=O)N(C)C +Nc1occ(-c2cccs2)c1C(=O)c1cccnc1 +COc1ccc(CC(=O)Nc2cccc(C(=O)NC3CC3)c2)cc1 +COc1cccc(C(=O)Nc2c(F)cccc2NC2CC2)c1F +COc1ccc(-c2nc(CN3CC(C)OC(C)C3)c(C)o2)c(F)c1 +CC(OC(=O)c1ccc(CNC(N)=O)cc1)c1ccccn1 +COC(=O)c1cccc(NC(=O)Cc2cccc(OCC#N)c2)c1 +N#Cc1ccc(N2CCc3ccccc3C2)c(F)c1 +CCc1cc(C2CCCN2C(=O)c2c(F)cccc2F)on1 +CCC(=O)Nc1ccc(NC(=O)c2cc(C)n[nH]2)cc1Cl +N#Cc1cnn(C(=O)c2ccc3ccccc3c2)c1N +O=C(NCCCn1cccn1)NCc1nc(-c2ccccc2)cs1 +COC(=O)c1ccccc1S(=O)(=O)N(C)CCO +CCCc1cc(C(=O)NC(c2ccccc2)C2CC2)[nH]n1 +CCOC(=O)C1=C(CC)NC(=O)NC1c1cccnc1 +CCN(C)c1ccc(C(=O)N2CCC(C(=O)N3CCCC3)CC2)cc1 +N#Cc1ccccc1C1NCCc2cc(F)ccc21 +O=C(Cc1cc2ccccc2[nH]c1=O)OCCNc1cccnn1 +O=C(Cn1c(=O)n(-c2ccc(F)cc2)c2ncccc21)N1CCCC1 +CCc1cc(C(N)=O)c(NC(=O)c2ccc3ccccc3c2)s1 +CC(NC(=O)Cn1ccccc1=O)c1nc2ccccc2[nH]1 +COc1ccc(N)cc1NC(=O)CSc1ccccn1 +CC(=O)Nc1c(Br)cc(C)c(C)c1C +CCCN(C(=O)c1cc(C(N)=O)c[nH]1)C1CCc2ccccc2C1 +CC1CCN(S(=O)(=O)NCCc2ccc3c(c2)OCO3)CC1 +CC(Oc1ccc(Cl)c(Cl)c1)C(=O)NCc1ccoc1 +CC(NC(=O)N1CCCC1c1cccs1)c1nnc2ccccn12 +CCn1cc(CN2CCCC(CN3CCOCC3)C2)cn1 +CN(C)C(=O)C1CCOC2CCN(c3nncs3)CC21 +Cc1cc(N(C)Cc2cnn(C)c2C)n2nc(C)c(C)c2n1 +COc1ccc(-c2nc3c(s2)CCN3)c(OC)c1 +c1ccc(Cn2ccnc2CSc2nnnn2C2CC2)cc1 +Cc1ccc(-c2cc(C)nc(C3CCN(S(C)(=O)=O)CC3)n2)cc1 +CC(C)CC(=O)Nc1ccnn1C1CCN(C(=O)C2CCOC2)CC1 +O=C(c1ccon1)N1CCCC1c1nc2cc(Cl)ccc2[nH]1 +Cc1ccc(NC(=O)Cn2ccccc2=O)cc1C(=O)NC(C)C +CCOc1cccc(C(=O)C(C#N)c2ccccn2)c1 +COc1ccc(CN2CC(C(=O)N3CC(C)OCC3C)CC2=O)cc1 +O=C(c1cc(=O)c2ccccc2o1)N1CCCC2(CCOC2)C1 +N#CCOc1cccc(CC(=O)NC2CC3CCC2O3)c1 +Cc1cc(NC(=O)CCc2ncc(-c3ccccc3)o2)n(CCC#N)n1 +O=c1cc(-c2cccnc2)c2ccc(OCc3ccccn3)cc2o1 +Cc1cccc(OC(C)C(=O)Nc2ccccc2NS(C)(=O)=O)c1 +CSc1nnc(SCC(=O)N2CC(C)CC(C)C2)s1 +Cc1nc(NCCNC(=O)c2snnc2C)cc(-n2cccn2)n1 +CCNC(=O)c1cccc(NC(=O)CNc2ccc(Cl)cc2)c1 +CCNC(=O)Cn1c(-c2cccs2)cc2ccccc21 +CC(C)CCOC1CCN(Cc2cnc(C3CCC3)s2)C1 +COCCOc1ccc(NS(=O)(=O)c2ccc(C)s2)cc1 +COc1ccc(Cl)cc1C(=O)OCC1CC(=O)N(C2CC2)C1 +Cc1sc(NC(=O)COc2ccc(F)cc2)c(C(N)=O)c1C +Cc1ccc(F)c(NC(=O)N(C)Cc2cccc(C#N)c2)c1 +CC(CCC(C)(C)C)NS(=O)(=O)Cc1cccc(C#N)c1 +CCn1ncc2ccc(NC(=O)CCc3ccc4c(c3)OCO4)cc21 +CN(c1cccc(NC(=O)C2CCCC2)c1)S(C)(=O)=O +COCC(=O)N1CCN(Cc2nc3c(F)cccc3[nH]2)CC1 +Cc1nc2c(c(=O)[nH]1)CCN(Cc1ccnc3ccccc13)C2 +Nc1cc2c(nn1)CCN(C(=O)c1cnc(-c3cccs3)s1)C2 +COc1ccccc1-c1ccc(C(C)N(C)S(N)(=O)=O)cc1 +COc1cccc2sc(NC(=O)c3cnccn3)nc12 +O=C(c1ccc(=O)[nH]c1)N(Cc1cccc(Br)c1)C1CC1 +N#Cc1ccc(OC2CCC(NC(=O)c3nccnc3N)CC2)nc1 +CC(C)(C)C(=O)NCC(=O)Oc1ccccc1Cl +CC(OC(=O)c1ccc(NC(N)=O)cc1)C(=O)NC1CCCCCC1 +O=C(Nc1c[nH]cc(Br)c1=O)C1CC1C1CC1 +COC(C)C(=O)OC(C)c1ccc2c(c1)OCCO2 +C=CCN(CC=C)c1cc(C(F)(F)F)cnc1N +CCN(CC)C(=O)Cc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CC(C)c1nnc(NC(=O)N(C)Cc2ccco2)s1 +C=CCn1c(CCNC(=O)c2ccc(OC)cc2)nc2ccccc21 +CCCc1n[nH]c(SCc2cc(=O)n3nc(C)sc3n2)n1 +Cc1nc(CNC(=O)C2CCN(c3cnccn3)CC2)c(C)s1 +Cc1ccc(-n2nc(C(=O)NCCCO)c3c2CCC3)cc1 +COc1ccc(-c2ncccc2CNC(=O)NCC(C)C)cc1 +COCc1cccc(-c2nc(C3CC3)nn2-c2ccccc2OC)n1 +Cc1cc(C(=O)NCCc2ccc(F)c(Br)c2)[nH]n1 +CC(C)S(=O)(=O)NC1CCc2c(Cl)cccc21 +CCOc1ccc(C(C)NC(=O)Nc2nccs2)cc1OCC +CC(C)NC(=O)c1ccc(CNC(=O)c2ccnc3[nH]ccc23)cc1 +COc1cc2c(cc1C(=O)NCc1ccccc1)OCCCO2 +Cc1csc(CN(C)CCc2ccc(Br)cc2)n1 +Cc1cc(C(=O)N2CC3CCC(C2)N(Cc2ccccc2)C3=O)no1 +COCc1c(C(C)C)c2cc3c(cc2[nH]c1=O)OCCO3 +O=C(CN1CCCCC1=O)NCC1(c2ccccc2)CCCC1 +O=C(Nc1ccc(Br)cc1)c1ccc(O)cc1 +CCOc1ccccc1OC1CCN(C(=O)c2ccoc2C)CC1 +C=CCn1c(SCc2cccnc2)nnc1-c1ccco1 +CCCCN(C)S(=O)(=O)c1ccc(OC)c(OC)c1 +COCCc1noc(CN2CCC3(CCCO3)CCC2=O)n1 +Cc1nnc2c(N3CCOCC3)nc3ccccc3n12 +Cc1cc2ncn(CC(=O)N3CCOC(C)C3)c2cc1C +COc1cc(Cl)c(C)cc1NC(=O)CCNC(=O)c1ccccc1 +Cc1cc(=O)c(OCc2ccccc2)cn1CC(=O)Nc1cccnc1 +C=CCNC(=O)Cn1nnc2c(C)nn(CC)c2c1=O +O=C(Nc1ccccn1)c1csc(-c2cc3ccccc3[nH]2)n1 +CCOc1c(CNc2nnnn2C)cccc1OC +Cn1c(=O)ccn(CC(=O)Nc2cc(F)c(F)c(F)c2)c1=O +CCOC(=O)C(O)Cc1cc(F)c(N(C)C)cc1F +CN(C)c1ccccc1NC(=O)NC1CCc2cc(F)ccc21 +Cc1cc(CN(C)C(=O)NCCC(=O)N2CCCCC2)no1 +NC(=O)C1CCCN(c2nn3cc(-c4ccc(F)cc4)nc3s2)C1 +Cc1cc(C(=O)Nc2ccc3c(c2)COC3)ccc1S(N)(=O)=O +CC(C)n1cnc2cc(NCc3ccccn3)ccc21 +CNC(=O)C1CCN(C(=O)c2ccc(C)cc2)CC1 +O=C(C1CC=CC1)N1CCC(O)C1Cc1cccnc1 +O=C1CSc2ccc(NC(=O)NCc3ccc(Cl)cc3)cc2N1 +CC1CC1C(=O)NCC1CCN(c2ccc(F)cc2)C1 +CC(C)c1[nH]c(-c2c[nH]c3ccccc23)nc1C#N +O=C(Nc1ccc(F)cc1)Nc1cc(F)c2[nH]c(=O)ccc2c1 +Cc1cc(C)c(C(=O)NCc2ccnc(OC(C)(C)C)c2)c(=O)[nH]1 +CC1CCC(C(N)=O)CN1C(=O)Cc1ccc2c(c1)OCCO2 +[H]N=c1n(CCO)c2ccccc2n1CCOc1ccccc1 +CCOC(=O)C1CCCN(C(=O)c2ccc3cn[nH]c3c2)C1 +O=C(Cc1csc(-c2nc[nH]n2)n1)NCCc1ccccc1Cl +CCn1cc(C(=O)NCc2ccc(Oc3ccc(F)cc3)nc2)cn1 +C=CCNC(=O)COC(=O)c1ccc2c(c1)OCO2 +CCc1cccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)c1 +CC(O)c1cccc(OCC(=O)Nc2ccc(OC(F)F)cc2)c1 +CCN(C)S(=O)(=O)NCc1ccnc(OC(C)(C)C)c1 +COc1cccc(-n2nnc(C(=O)OCc3ccc(F)cc3)c2C)c1 +CN(C)S(=O)(=O)c1cc(C(=O)Nc2ccn(C)n2)ccc1Cl +CCOc1cc2c(cc1NC(=O)c1ccc[nH]c1=O)OC(C)C2 +CN(C(=O)c1cc2c(nc1N)CCCCC2)C1CCCCC1 +Clc1ccc(-c2ccnc3ncnn23)c(Cl)c1 +CC(CN1CCCC1=O)NC(=O)Nc1cc(-c2ccccc2)on1 +O=C(NCc1ccncc1)C1(c2ccccc2)CCC1 +CC(C)CC(C#N)NC(=O)CCc1c[nH]c2ccccc12 +O=C(NCCC(=O)N1CCCCC1)c1ccccc1 +COc1cc(-c2nc(-c3ccccc3O)n[nH]2)cc(OC)c1OC +CC(Oc1ccccc1)C(=O)Nc1ccc2c(c1)OCCO2 +CC(Cn1cncn1)C(=O)N1CCCCC1CCc1ccccc1 +COCc1noc(-c2ccc(N(C)Cc3ccncc3C)nc2)n1 +Cn1cc(C(=O)NC2CN(S(C)(=O)=O)C3CCCOC23)cn1 +CCCCn1ncc(-c2ccc3c(c2)OCO3)c(CO)c1=O +O=C(NC1CCSc2ccc(F)cc21)N1CCOCC1 +Cc1cc(Cn2ncc(N(C)CCc3ccccc3)cc2=O)on1 +O=C(c1ccc(Cl)cc1Cl)N1CCCC(n2cncn2)C1 +CCn1ccnc1SCc1coc(-c2cccs2)n1 +Cc1cc(C)c(CNC(=O)c2ccc(=O)n(C)n2)c(=O)[nH]1 +Cc1csc(NC(=O)c2oc3ccccc3c2COC(C)C)n1 +Cc1cccc(NC(=O)c2cccc(N(C)S(C)(=O)=O)c2)c1 +CNc1ncccc1C(=O)Nc1cc(C)ccc1F +Cc1noc(C2CCCN2C(=O)C2COc3ccccc3O2)n1 +Cc1ccc(Cl)c2ccc(NC(=O)Cn3cnnn3)nc12 +O=C(Nc1nnc(-c2ccno2)o1)c1cccc(F)c1 +COC(=O)C1CCC(=O)N1c1cc(OC)ccc1OC +COCCNc1cc(-c2cncc(Br)c2)nc(C)n1 +CCn1nccc1C(=O)N1CCCCC1c1nncn1CC1CC1 +COc1cc(CC(=O)Nc2ccc(CC#N)cc2)cc(OC)c1OC +Cc1c(NC(=O)NC(C)C(C)C)cccc1C(N)=O +CN(C(=O)c1cc(F)ccc1-n1cnnn1)c1ccccc1 +CNc1nc2c(c(C(=O)N3CCCC3)n1)CN(C(=O)C1CCC1)CC2 +CCN(CC)C(=O)CN(C)C(=O)C1CCC(=O)N1 +CCOc1ccc(CNC(=O)NCCN2CCOCC2)cc1F +NC(=O)c1ccsc1NC(=O)CCSc1ncccc1Cl +COC(=O)c1c(C)nn(-c2cccc(C)c2)c1-n1cccc1 +c1ccc(-c2cnc(CN3CCc4cncnc4C3)o2)cc1 +Cc1c2c(nc3cc4c(cc13)OCO4)-c1cnn(C)c1CC2 +O=C(C1COc2ccccc2O1)N1CCOC2CCCCC21 +COC1CCN(C(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)CC1 +CC(C)NC(=O)Nc1nc2c(s1)CN(C(=O)C1CCCC1)CC2 +CC(C)CC(C(=O)N(C)CC1CC1)N1CCCCC1=O +CCn1cc(CCC(=O)Nc2cnc3cc(OC)ccc3c2)c(C)n1 +CCOC(=O)C(C)Sc1nnc(-c2ccc(F)cc2)o1 +CN(C(=O)C1CCOCC1)C1CCN(c2ccc(F)cc2)CC1 +CCCNC(=O)CNC(=O)NC(C)c1ccc(CC)cc1 +c1ccc(-c2cnn(Cc3noc(-c4cccs4)n3)c2)cc1 +COc1cccc(C(=O)NCc2ccc3c(c2)CCN3C(C)=O)c1 +O=C1Cc2cc(-c3csc(C4CC4)n3)ccc2N1 +C=CCNS(=O)(=O)c1ccc(C(=O)OC2CCCC2)cc1 +COc1cccc(C2CCC(OC)c3nc(N)nn32)c1 +Cc1sc2nc[nH]c(=O)c2c1S(=O)(=O)N1CCCCC1 +Cc1cn[nH]c1C1(C)CCCN(C(=O)c2ccc(F)cc2)C1 +O=c1n(Cc2ncc(-c3cccs3)o2)nc2ccccn12 +CCOC(=O)c1c(C)[nH]c(C(=O)NC2CC2)c1C +CCc1noc(CNc2ccccc2CN2CC(C)OC(C)C2)n1 +CCCc1nc2ccccc2c(=O)n1-c1ccccc1 +Cc1cccc(-c2cc3n[nH]c(=O)n3c(NCc3ccc(F)cc3)n2)c1 +COc1cccc(N2CCN(C(C)CC#N)CC2)c1 +Cc1cccc(S(=O)(=O)c2c(C)cc(C)[nH]c2=O)c1 +CCC(=O)Nc1ccc(S(=O)(=O)N(C(C)C)C(C)C)cc1 +CCCc1nc(C(=O)N2CCN(S(=O)(=O)CC)CC2)cs1 +O=c1[nH]c2ccc(-c3[nH]nc4c3CNCC4)cc2o1 +CSc1ccc(NC(=O)N(C)Cc2ccccn2)cc1 +CCC(=O)N1CCCc2ccc(NS(=O)(=O)CC(C)C)cc21 +COc1cccc(CN(C)C(=O)c2ccccc2-n2ccnn2)c1 +Cc1c(C(=O)Nc2ccc3oc(=O)ccc3c2)nnn1-c1ccccc1 +CC(C)(CO)Nc1ccc(NC(=O)C2CCCCC2)cn1 +COc1ccc(C)cc1S(=O)(=O)NCc1cn[nH]c1 +O=C(COc1ccccc1NC(=O)C1CC1)Nc1cccc(Cl)c1 +CC(=O)Nc1cccc(NC(=O)c2cc3cc(Cl)ccc3o2)c1 +Cc1ccc(CC(=O)Nc2ccn(-c3ncccc3Cl)n2)cn1 +COCCCOc1ccccc1NC(=O)c1[nH]nc2c1CCCC2 +COCCOC(=O)N1CCCC(C)(c2ccccc2)C1 +Cc1nc(C)c(C2NCCc3c(C)ccc(F)c32)s1 +Cc1ccc(C(CNC(=O)c2cc(C)cc(C)c2)OCCO)cc1 +Cc1nnc(-n2nnc(C#N)c2Cc2cccs2)s1 +CCOC(=O)c1cc(-c2cc(C)cc(C)c2OC)nn1CCO +CCOC(=O)CN(C)C(=O)COc1ccccc1F +CN(Cc1ccco1)C(=O)c1ccc2c(c1)OCCCO2 +CCOC(C)c1noc(CN2CCN(C(=O)CC)CC2)n1 +Cc1ccc(CN(C)C(=O)c2cc3c(cc2O)OCO3)s1 +CC(C)c1cccc(OCC(=O)NCC2CN3CCCCC3CO2)c1 +CCC1CCCC(NC(=O)NCc2ccnn2C)C1 +CC(C)(C)OC(=O)NCC1CCCN(C(=O)Nc2nccs2)C1 +CCOC(=O)C1=C(C)N(C)C(=O)NC1c1sccc1C +Cc1cc(C)nc(Nc2nc3sc(C)c(C)c3c(=O)[nH]2)n1 +Cc1nccc(CNc2ccccc2S(=O)(=O)N(C)C)n1 +CCS(=O)(=O)c1ccc(NC(=O)c2ccncc2)cc1 +CC(=O)Nc1nc2ccc(CC(=O)NCCC(C)C)cc2s1 +COCCn1ccc(NC(=O)C2CN(Cc3ccccc3)CCO2)n1 +COc1ccc(-c2nccnc2C#N)c(Cl)c1Cl +CC(NC(=O)N1CCN(CC(F)F)CC1)c1ccc(F)c(F)c1 +COCC(C)N(C)C(=O)Cn1ncc2ccccc2c1=O +CCS(=O)(=O)NCCCn1nc(-c2ccc(C)cc2)ccc1=O +COc1ccc(N(Cc2cccs2)C(=O)CCC2CCCO2)cc1 +O=C(N1CCCC(CN2CCOCC2)C1)C1(c2ccccc2)CC1 +CC(CNS(N)(=O)=O)c1nc(-c2ccccc2)no1 +CCc1nnc2n1CCN(C(=O)CCc1c[nH]c3ccccc13)C2 +CCC(=O)Nc1ccc(-n2cnc(C(=O)NC)c2)nc1 +O=C(CNC(=O)Nc1cccc(OC(F)F)c1)Nc1ccccc1 +CN(Cc1ccc(C#N)cc1)C(=O)NCCNC(=O)c1cccnc1 +CCSc1ccc(NC(=O)C(C)n2cncn2)cn1 +CC(C)C(C(=O)N1CCc2cnccc21)N1CCCC1=O +O=C(NCCc1ccccc1)NC1CCCCNC1=O +Cc1cc(NCc2nnc3n2CCCCC3)nc(-c2ccccn2)n1 +COc1cccc(C(=O)Nc2c[nH]c(=O)[nH]c2=O)c1 +COc1cccc(-c2ncc(CN3CCOCC3CC(N)=O)s2)c1 +COc1cccc(OC)c1C(=O)Nc1ccc(C)cc1 +Cc1cc(=O)n2nc(NCc3ccccc3F)nc2[nH]1 +O=C(c1cc(-n2ccnc2)ccn1)N1CCn2c1nc1ccccc12 +CCNC(=O)CN(c1ccc(C)cc1)S(C)(=O)=O +COCCNS(=O)(=O)c1cc2c(cc1C)CCN2C(C)=O +COC(=O)c1cc2oc(C)cc2n1CC(=O)Nc1ccc(OC)cc1 +Cc1nn(-c2c(F)c(F)cc(F)c2F)c(N)c1C#N +Nc1ccc(S(=O)(=O)Nc2nccc(C(F)(F)F)n2)cc1 +COc1cc(CC2COc3c(cccc3OC)C2)ncn1 +Cc1ccccc1NC(=O)NC1CCCc2ccccc21 +CNc1nnc(-c2cnn(-c3cccc(Cl)c3)c2C)s1 +CC(NC(=O)Nc1ccc(OCC(F)(F)F)nc1)c1ccccn1 +O=C1c2ccccc2NC(c2cnn(-c3ccccc3)n2)N1C1CC1 +COc1ccc(C)cc1CCNCc1cn(C)nc1-c1ccncc1 +Cc1ncc(CNC(=O)Cc2csc(N3CCNC3=O)n2)s1 +COc1ccccc1C(=O)N(C)C(C#N)c1cccc(Cl)c1 +CC(C)(C)c1nc2cc(NC(=O)NCc3ccncc3)ccc2o1 +O=S(=O)(N1CCCC1c1ccco1)N1CCCC2CCCC21 +CCOCCCNC(=O)NC(C)c1ccc(C#N)cc1 +CC(=O)NCCc1nc(CC(C)C)nn1-c1ccc(Cl)cc1C +COc1cc2nc(CCC3CCCC3)oc(=O)c2cc1OC +CCc1cc(C(=O)NCC(F)(F)F)sc1C +Cn1cnnc1CNC(=O)CNC(=O)c1ccc(N)cc1 +CC1OC(c2cccs2)N=C1CSc1nc(N)n[nH]1 +CN1c2ccc(N)cc2N(CCO)CC1c1ccccc1 +COc1ccc(F)c(NC(=O)c2cc(C(C)C)nn2C)c1 +CCOCC(O)CN1CCOC(c2ccccc2Cl)C1 +Cc1cccc(C)c1OCCCNC(=O)NC1CC1 +CCS(=O)(=O)c1ccccc1C(=O)Nc1cc(F)cc(F)c1 +CCNc1ccc(C(=O)NCCCc2c(C)noc2C)cn1 +COCCCNC(=O)CN(C)C(=O)c1cc(F)cc(F)c1 +CCCCc1nnc(NC(=O)C2CCCN(C(=O)OCC)C2)s1 +Cc1cnn(CC2CCCCN2C(=O)Cc2cccc(F)c2)c1 +Cc1cnc(CNC(=O)NC2(C)Cc3ccccc3C2)s1 +COC1CCN(S(=O)(=O)c2ccccc2)C1Cc1ccccc1 +COc1ccc(CN(C(=O)c2[nH]c(C)c(C(C)=O)c2C)C2CC2)cc1 +COc1ccc(CCC(=O)Oc2ccc3cn[nH]c3c2)cc1F +CCOC(=O)c1cn2cc(Br)cc(C(F)(F)F)c2n1 +Nc1ccc2nc(CC(=O)N3CCCCC3)cn2c1 +CNC(=O)c1ccccc1Cn1ccsc1=NC(=O)c1ccco1 +Cc1cc(C)c(S(=O)(=O)NCCNC(=O)OC(C)(C)C)c(C)c1 +CCCc1nnc(NC(=O)c2cnc(C)nc2N)s1 +Cc1csc(CCCNC(=O)NC2CCOC2c2ccccc2)n1 +CC(C)COC1CC(OC(=O)c2ncn(-c3ccccc3)n2)C1(C)C +Cc1cnn(CC2CN(Cc3nnc(C(C)C)o3)CCO2)c1 +Cc1cc(-c2nn3c(-c4cc(C(C)(C)C)[nH]n4)nnc3s2)on1 +Cc1cc(C(=O)Nc2sc(C(C)C)cc2C(=O)OC(C)C)no1 +O=C(NC1CC1)C1CCCN(C(=O)C2CCCCC2)C1 +COc1cccc(-c2nsc(NC(=O)c3ccc(C)nc3C)n2)c1 +COc1ccc(OC)c(CNC(=O)c2cn3nc(OC)ccc3n2)c1 +CN(C)S(=O)(=O)c1cc(Cl)c(Cl)cc1Cl +O=C1OCc2ccc(NS(=O)(=O)NCc3ccccc3)cc21 +COc1ccc(N)cc1N1CCN(C(=O)C(C)C)CC1 +OC(CNc1cccc(F)c1)c1ccc2c(c1)OCO2 +Cc1noc(C)c1C(C)C(=O)N1CCN(Cc2ccccc2)CC1C +Cc1ccc(C(=O)NC2CC2)cc1NCc1nnnn1-c1ccccc1 +Cc1cnn(CCC(=O)Nc2ccc(SC(=O)N(C)C)cc2)c1 +O=C1OCCN1CCn1nnn(-c2ccccc2)c1=O +Cc1ccc(NC(=O)c2cn3ccccc3n2)cc1 +O=C(CCCCc1ccccc1)N1CCOCC(CO)C1 +CC(C)Cn1nccc1NC(=O)c1cc(C(C)C)[nH]n1 +CN(CC(=O)N1CCN(C(C#N)c2cccs2)CC1)CC(F)F +Nc1ccccc1NS(=O)(=O)c1ccc2c(c1)CCC2 +CCOC(=O)C1CCCN(C(=O)NCc2ccccc2F)C1 +Cn1nccc1C(=O)N1CCCC(C)(c2[nH]ncc2C(N)=O)C1 +CCN(CC)C(=O)c1ccccc1NC(=O)N1CCC(C)CC1 +COC(=O)c1cc(-c2ccc(Cl)cc2)[nH]c1N +COC(=O)c1cccc(C(=O)NCCCn2ccc3ccccc32)n1 +CC1CCC(N(C)C(=O)COc2ccccc2)CC1 +Cc1n[nH]cc1NC(=O)CN(C)C(=O)c1ccsc1 +Cc1ccccc1CN(C)S(=O)(=O)c1ccccc1 +O=C(NC1CCCC1)C1(c2cc(-c3ccco3)on2)CC1 +CC(C)Nc1cc(S(=O)(=O)N(C)C)ccc1OC(C)C +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)N1CCc2sccc2C1 +Cc1sc2ccccc2c1S(=O)(=O)NCCN1CCOCC1 +Cc1ccc(C(C)NC(=O)c2cnn(C(C)(C)C)c2)s1 +COc1cc2ncn(CC=C(C)C)c(=O)c2cc1OC +Cc1nc2cc(C(=O)N3CCn4cccc4C3C)ccc2n1C +COc1ccnc(NC(=O)Cn2nnnc2C(C)C)c1 +CC(C)CCCOC(=O)C1CC(=O)Nc2ccccc21 +COc1ccc2c(c1OC)C(Cc1ccccc1)NCC2 +CCCOc1cc(CN2C(C)COCC2C)ccc1OC +CC(C)(C)C(NC(=O)c1cc(C2CC2)nc2ccc(F)cc12)C(N)=O +CCCNC(=O)c1cccc(CNC(=O)NCc2cscn2)c1 +COc1ccc(S(=O)(=O)N(C)C(C)C(C)C)cc1N +Cn1ccc(NC(=O)c2ccc(F)cc2Cl)n1 +OCC1(CC2CC2)CCCN(c2nccnc2N2CCCC2)C1 +Cc1cc(CN(C)C(=O)c2ccc3c(c2)CCCC3)no1 +CCc1onc(C)c1NC(=O)NCc1ncc(-c2ccccc2)[nH]1 +CCCN(CCC)C(=O)COc1ccc[nH]c1=O +CCC(=O)Nc1nnc(S(=O)(=O)NC(C)C)s1 +CNC(=O)c1cn(CC(C)C)c(=O)c2ccccc12 +Cc1cccn2cc(Cn3c(S(C)(=O)=O)nc4ccccc43)nc12 +NC(=O)c1cc(NC(=O)CSc2nc3ccccc3o2)ccc1F +C=C(C)Cn1c(=O)n(CC(=O)OC)c(=O)c2c3c(sc21)CCC3 +CC1CC1CNC(=O)CCNS(=O)(=O)c1cccs1 +CCc1nnsc1C(=O)NCCc1cccc(C)c1 +N#CC(C(=O)c1ccc(F)cc1)c1nc(-c2ccccc2)cs1 +CC(C)(C)NC(=O)CCSc1nnc(-c2ccco2)o1 +CC(C)c1ccccc1NC(=O)C1CCCN1C(=O)c1cccs1 +C=CCNC(=O)NCC#CCOc1ccccc1CC=C +CCN(CCO)C(=O)c1cc(Cl)ccc1Cl +Cc1cc(NC(CO)CC(C)C)nc(-c2ccccn2)n1 +O=C(COC(=O)C1COc2ccccc2O1)c1ccc2c(c1)CCC2 +Cn1c2ccc(N)cc2n2c(-c3ccc4c(c3)OCO4)nnc12 +COc1cc(N)cn2cc(-c3ccc(F)cc3)nc12 +Cc1ccncc1NC(=O)N1CCC(C(=O)c2ccccc2)CC1 +Cn1cc(CNC(=O)C2CCCCC2C(F)(F)F)cn1 +COc1ccc(CCNC(=O)c2ccn(-c3ccccc3)n2)cc1 +NC(=O)CCn1c(CS(=O)(=O)c2ccccc2)nc2ccccc21 +COCCNS(=O)(=O)c1ccc2c(c1)CC(C)N2C(C)=O +Cc1nc2ccc(C(=O)NC(C)Cc3ccsc3)cc2nc1C +O=S(=O)(NCCc1ccsc1)c1ccc(Br)cc1 +COc1ccccc1NC(=O)CSc1cn(C)c2ccccc12 +CCC(Sc1nc(=O)ccn1C1CC1)c1ccc(F)cc1 +CS(=O)(=O)N1CCCC1C(=O)Nc1nc2ccc(F)cc2s1 +CCN(CC(O)c1ccc(C)cc1)C(=O)Cc1c(C)noc1C +CCN(CC)c1ncnc(Oc2ccccc2)c1N +Cc1noc(C)c1CCCNC(=O)NCCC(F)(F)F +CCc1cnccc1C(=O)NC(C)Cn1cncn1 +Oc1ccc2c(c1)OCC2NCCc1ccc(F)cc1 +O=C(NCc1ccc(Cl)cc1)c1ccc(-n2cnnc2)cc1 +Cc1ccc(C(=O)NCC(=O)N(C)Cc2cccc(Cl)c2)cc1C +O=C(Cc1ccc(N2CCCC2=O)cc1)Nc1nc(C2CC2)cs1 +COc1ccc(S(=O)(=O)C(C)C(=O)NC(C)c2ccccc2)cc1 +CC(=O)N1CCN(CC(=O)Nc2nc3ccc(F)cc3s2)CC1 +O=C(NCc1ccc(Cl)cc1)c1cc2n(n1)CCCO2 +CCC(C)N1CCN(C(=O)c2n[nH]c(N)n2)CC1 +O=C(Nc1ccccc1)N1CCN(C2Cc3ccccc3C2)CC1 +CC(C)(O)CCc1ccc(C(=O)NCC2CCC(=O)N2)cc1 +CCc1nc(NCc2ccccn2)cc(OCC(C)C)n1 +COc1ccc(-c2cc3nccc(-c4cc(O)ccc4O)n3n2)cc1 +Cc1cc(NC(=O)COC(=O)COc2ccc(C)c(C)c2)no1 +COc1ccc(C(=O)N(C)Cc2ccccc2F)c(OC)c1OC +Cc1nccn1-c1ccc(NC(=O)COc2ccccc2F)cn1 +O=C(Nc1cc(C2CCCCCC2)[nH]n1)C1CCOCC1 +Cc1occc1C(=O)OCc1cc(=O)oc2c(C)c(O)ccc12 +COc1cc2c(C(=O)NCCC(C)C)cn(C)c(=O)c2cc1OC +CNC(=O)c1ccc(NC(=O)CNc2ccc(Cl)cc2)cc1 +Cc1ccc2oc(SC(C)c3nc(C4CC4)no3)nc2c1 +COC(=O)c1ccc(N2CCN(Cc3csc(C)n3)CC2)nn1 +CCOc1ccccc1OC(=O)C(C)NC(=O)C(C)(C)C +O=C(Cn1c(=O)oc2cc(CO)ccc21)N1CCCC1 +Cc1ccc2ncn(CC(=O)NCCCc3ccccc3)c(=O)c2c1 +O=C(NCCc1nccs1)N1CCCCCC1c1ccncc1 +NC(=O)CNC(=O)Cc1csc(-c2ccccc2Cl)n1 +Cc1cccc(-c2nc(C)nn2CC(=O)NCC(F)(F)F)c1 +COc1cc(C#N)ccc1OCc1cccc(F)c1 +CCN(Cc1cc(Br)ccc1F)C(=O)CCC(=O)OC +O=C(Nc1cc(-c2cccs2)nn1CCO)c1ccco1 +COc1ccc2ccccc2c1CNc1cncnc1 +Cc1cc(C)n2c(CNC(=O)CC3C=CCC3)nnc2n1 +CS(=O)(=O)NC(c1ccccc1OC(F)F)C(F)(F)F +CCN(CC(C)C#N)C(=O)c1ccc(Cl)cc1 +CNS(=O)(=O)CCNC(=O)c1cccc(Cn2cccn2)c1 +Cc1nc(C2(NC(=O)c3cc4ccccc4oc3=O)CCCC2)no1 +CC(C)COc1ncc(CNC(=O)C(C)n2cccc2)cc1Cl +Cc1nn(CC(C)C)c(C)c1CC(=O)N(CC(N)=O)C1CCCC1 +O=C(Cc1csc(-c2ccoc2)n1)N(CC1CC1)CC1CC1 +Cc1csc(CN2CCN(C(=O)c3cc4ccccc4o3)CC2)n1 +O=C(NCc1cn[nH]c1)c1ccc(OC(F)F)cc1 +CC(C)(C)c1ccc(OCCNC(=O)C2CCC(=O)N2)cc1 +NC(=O)CSc1nccn(-c2cccc(Cl)c2)c1=O +COc1ccnc(NC(=O)c2ccc(=O)n(-c3ccccc3)n2)c1 +COCCNC(=O)c1cccc(-n2nnc3cccnc32)c1 +Cc1nn(C)c(C)c1CCNS(=O)(=O)c1ccc(C(C)(C)C)cc1 +CC1(C)CN(C(=O)c2cc(-c3ccccc3)no2)CC1(C)O +CCc1cccc(CC)c1S(=O)(=O)Nc1ccc(CC(N)=O)cc1 +CCOc1ccc(C(C)=O)cc1NC(=O)C1CCC1 +N#Cc1ccc(-c2ccc(C(=O)N3CCCCC3)cc2)cc1 +CCn1nc(CNC(=O)c2ccnc(NC)c2)c2ccccc21 +Cc1noc(-c2ccc(NC(=O)c3ccccc3C)cc2)n1 +COc1c(O)ccc2c1C(c1cccc(N(C)C)c1)NCC2 +CCc1c(C)nc(SCC(=O)Nc2ccccc2C)[nH]c1=O +CSc1cccc(-n2nnc(C(=O)OC(C)C)c2N)c1 +CCOC(C)c1noc(CNc2cc(F)ccc2Cl)n1 +Cc1nc(C(=O)N2CCN(c3ccccc3)CC2)co1 +Cc1nc(-c2cc(C(=O)Nc3cc(F)ccc3C)n(C)c2)cs1 +CC(=O)Nc1ccc(CC(=O)N(C)C2CCCC(C)C2)cc1 +Cc1cccc(-n2ccnc2SCC(=O)NCc2cccs2)c1 +Fc1ccc(NCc2nnc3n2CCCCC3)cc1 +Cn1cc(CNc2c(Cl)cccc2C(F)(F)F)cn1 +Cc1nn(C)c2ncc(C(=O)NCC3CN(CC(C)C)CCO3)cc12 +O=C(NCC1CC1)c1ccc2c(c1)CC(=O)N2Cc1ccc(F)cc1 +Cc1onc(-c2ccccc2Cl)c1-c1nc(C2CCOC2)no1 +CNC(=O)c1ccc(Oc2ncnc3ccccc23)cc1 +CN(C)C(=O)CSc1nnc(-c2cnccn2)o1 +c1ccc(-c2cc(CNCCc3ccco3)c3nnnn3c2)cc1 +CCOC(C)C(=O)Nc1ccc(OCC(N)=O)cc1 +CCCCCC(=O)N1CCC(C(=O)OC)c2ccccc21 +CC(=O)NCC1CCCN(C(=O)Nc2cc(C)ccc2C)C1 +CC(=O)N1CCN(C(=O)CC2C(=O)Nc3ccccc32)CC1 +CC(C(=O)NC1CC1)N1CCN(CC(=O)Nc2cccc(F)c2)CC1 +O=C(NCc1cc(F)ccc1Br)N1CCOC(CO)C1 +O=C(Nc1nc(-c2ccccc2)ns1)c1cccnc1 +CC1CN(C(C)(C)CNc2nnnn2-c2ccccc2)CC(C)O1 +Cn1cc(C(=O)N2CCN(C(=O)C3CCCO3)CC2)c2ccccc21 +CN(CCc1ccccn1)C(=O)NCC1(c2ccc(F)cc2)CC1 +CCC(CCO)NC(=O)Nc1ccc(OC)c(C)c1 +COc1ccc(Cc2nc3cc(C)ccn3n2)cc1 +O=C(CCCC(O)c1cc(F)ccc1F)NCc1ccco1 +Cc1cc(-c2csc(S(=O)(=O)NCc3ccccc3C)c2)on1 +CN(C)c1ccc(C(=O)Nc2ccc3oc(C4CC4)nc3c2)cc1F +O=C(NCC(O)c1ccc2c(c1)OCO2)c1ccccc1 +COc1ccccc1C(C#N)N(C)C(=O)c1ccc(C)cc1 +O=C(CCc1nc2ccccc2s1)NC1CCc2c(O)cccc21 +CCc1nnsc1C(=O)NCc1ccc(C(=O)OC)cc1 +CC(C)Cc1nc(CN(C)c2ccnc(C(F)(F)F)n2)no1 +Cc1nc(NC(=O)c2snnc2C)sc1C +CCCS(=O)(=O)NCCn1ccc(-c2ccccn2)n1 +O=C(c1ccc2[nH]nnc2c1)N1CCCC1c1ccncc1 +COc1ccccc1C(O)C(=O)N1CCNCC1 +CCN(C)C(=O)c1cccc(C(=O)Nc2cc(-c3ccncc3)n[nH]2)c1 +Cc1ccccc1NC(=O)Cc1csc(-n2cccc2)n1 +CC(=O)c1c[nH]c(C(=O)Nc2ccc(C)c(C)c2)c1 +NC(=O)Cn1nnc2sc(-c3ccccc3)cc2c1=O +COc1cccc(NC(=O)CN(C)C(=O)c2ccoc2)c1 +Cc1ccc(-n2nnc(C(=O)NCc3ccccc3)c2N)cc1 +CC=CCC(=O)N1CCC2(CC1)c1nc[nH]c1CCN2C(=O)COC +O=C(CNC(=O)N(Cc1ccccc1)CC1CCCO1)N1CCCC1 +Cc1c(C(=O)NCC2CC2C)[nH]c2c1C(=O)CCC2 +CC1(CNC(=O)Nc2ccc(Oc3cccnc3)nc2)CCCO1 +COC(=O)C1CCn2nc(-c3cccnc3)nc2C1 +CCN(C(=O)C1CCCO1)C(C)c1cccc(C(F)(F)F)c1 +Cc1ccc(N2CCC3(CC(NS(C)(=O)=O)CCO3)C2)nn1 +CCc1ccc(S(=O)(=O)NCc2ccc(OC)c(F)c2)cc1 +CCN(CCO)C(=O)c1cn(C)nc1C(F)(F)F +CN1CCN(C(=O)CCC(C)(C)C)C(c2ccccc2)C1 +Cc1ccc(C(=O)NCC(C)c2c(Cl)cccc2Cl)cn1 +O=C(CN1CC(Cc2ccccc2)CC1=O)N1CCOCC1 +CCc1nsc(N2CCN(Cc3cnc4cnccn34)CC2)n1 +Cc1ccc(C(=O)OCC(=O)Nc2ccccc2)cc1O +Cc1oc(C)c(C(=O)NC(C)c2ccncc2)c1C +CCc1nc(NCc2ccccn2)c2c(n1)c(C)nn2C +CCOCCCNc1ncnc2onc(-c3ccc(F)cc3)c12 +OCCN(CCc1ccccc1)Cc1c(F)cccc1F +COCC(=O)N(C)CC(=O)N(c1ccc(C)cc1)C(C)C +C=CCNC(=O)c1onc(S(=O)(=O)CC)c1N +CCOC(=O)N1CCN(C(=O)c2ccc(C)cc2C)CC1 +C=CCn1c(C(O)c2ccccc2)nc2ccccc21 +Cc1cc(C(=O)OCCCC(N)=O)nn1-c1ccccc1 +CCC(C)(C)NS(=O)(=O)c1cc(OC)c(OC)cc1F +O=C(CCCOC(=O)c1ccc(O)cc1)c1ccccc1 +CS(=O)(=O)NCCc1ccc(C(=O)NCc2cccnc2)cc1 +CC(=O)NCCNC(=O)NCC(C)c1nc(-c2ccccc2)no1 +O=C(NC1CCN(c2ccccc2)CC1)c1csnn1 +COc1cccc(C(=O)NC(C)CC(C)C)c1OC +CCC(C)NC(=O)NCc1cccn1Cc1cccc(F)c1 +CCc1nc(COc2ccc(Cl)cc2)sc1CO +CN(CC(C)(C)O)C(=O)c1cnc(Cc2ccccc2)s1 +COc1nc2ccccc2cc1-c1ncccc1C#N +O=C(CCn1cncn1)NC1CCN(c2ccccc2)CC1 +COc1ccc(S(=O)(=O)N=c2cccc(C)[nH]2)cc1 +CCC(=O)CSc1ncnc2c1cnn2-c1ccc(F)cc1 +COCc1ccccc1C(=O)Nc1cc(C)cc(C)n1 +CSc1cccc(NC(=O)n2ncc3ccccc32)c1 +CCOCCCNS(=O)(=O)c1ccc2c(c1)NCC(C)(C)O2 +Cc1nnc(SCC(=O)c2ccc(Br)cc2)o1 +CN(C)C(=O)CCSc1nc2ccccc2n1Cc1ccccc1 +CC(=O)c1nc2ccccc2n1C1CCN(C(=O)OC(C)(C)C)CC1 +Cc1ccc(NC(=O)CCc2c(C)nn(C)c2C)cc1Cl +CS(=O)(=O)c1cccc(NC(=O)C2CCC2)c1 +COc1cc(NCC(=O)N2CCCCC2C)c(OC)cc1Cl +COCCNC(=O)C1(C)CCC(=O)N1Cc1ccc(Cl)cc1 +Cc1cc(N)cc(C(=O)OCC2CCOCC2)c1C +Cc1cccc(N(C)C(=O)c2ccc(CSc3ncn[nH]3)cc2)c1 +O=C(CCC(=O)c1ccc(F)cc1F)NCCc1ccccn1 +CCCCN(C(=O)c1cnc2c(c1)c(C)nn2C)C(C)CC +O=C(CNc1ccc(F)c(F)c1)NC1CCOCC1 +CC(=O)N1CCC(c2cc(N(C)C)nc(-c3cnccn3)n2)CC1 +Cc1ccc(CN2CCC3(CC(Nc4ncccn4)CO3)C2)s1 +COCc1ncc(C(=O)N2CCCc3ccccc32)c(N)n1 +CC1Cc2nc(N)nn2CC1c1ccc2ncccc2c1 +Cc1cc(NC(=O)c2ccc(-c3ccccc3)[nH]c2=O)no1 +COc1ccc(C(=O)Nc2nc(-c3ccc(C#N)cc3)cs2)cc1 +CCS(=O)(=O)c1ccc(-c2cc(C#N)c(C)o2)cc1 +CSc1ccc(S(=O)(=O)Nc2ccc(NC(C)=O)cc2)cc1 +CCCn1c(CCC(=O)NC)nc2cc(S(N)(=O)=O)ccc21 +Brc1cccc2c(NCCn3cccn3)ncnc12 +COCc1c(Br)cccc1NCc1cnccn1 +O=C(Oc1ccccc1)N1CCN(C(=O)c2cccnc2)CC1 +CCNC(=O)NC1CCC(OC(=O)Cn2c(C)csc2=O)CC1 +CN(C)c1ccccc1NC(=O)c1ccc(=O)n(C)c1 +CC(=O)c1ccc(C(=O)Nc2nnc(Cc3ccc(F)cc3)o2)cc1 +Cc1nc(C)n(CC2CCCN2C(C(N)=O)c2ccccc2)n1 +CCn1c(NC)nc2c1c(=O)n(C)c(=O)n2CC(C)C +FC(F)(F)CN1CCC(c2c[nH]c3ccccc23)CC1 +CC1CCCCC1NC(=O)NCCCOCc1ccco1 +Cc1cc2n(n1)CCC(=O)N2CC(=O)NCc1ccc(C)o1 +O=C(Cn1cncn1)N1CCCC1c1ccc2c(c1)OCCO2 +CC(NS(C)(=O)=O)C(=O)N(C)Cc1ccc(OC(F)F)cc1 +CCOC(=O)c1ccccc1NC(=O)CCc1cccc(N)c1 +CCN(CC)C(=O)c1cnn(-c2ccc(C)nn2)c1N +Cc1cc(C)cc(NC(=O)Cn2c(C)nc3ccccc32)c1 +Cc1cccc(C(=O)N2CCCC2C(=O)N2CCN(C)CC2)c1O +O=C(c1cccc(-n2cnnc2)c1)N1CC=CC1CO +CN(C)C(=O)Cc1nc(CN2CCc3ccc(Cl)cc3C2)cs1 +N#CCc1c(C#N)c(N)nc(NCCCN2CCOCC2)c1C#N +COc1ccc(OC(=O)Cn2nc(C)c3ccccc3c2=O)cc1 +O=C(Cc1cccc(O)c1)N1CCc2ccccc2C1 +CCN(CC)S(=O)(=O)c1ccc(N2CCCCC2=O)cc1 +CCCC(NC(=O)c1ccc(N2CCOCC2)cc1)c1ccccc1 +CNC(=O)c1nc(Cn2nc(-c3ccc(F)cc3)ccc2=O)no1 +CC(C)c1nnc(NC(=O)c2csc(NC3CC3)n2)s1 +N#CC(CC(=O)NCc1ccccn1)c1ccc(Cl)cc1 +CC(=O)N1CCN(C(=O)C2CC(=O)N(Cc3ccco3)C2)CC1 +CCNc1nnc(-c2sc(-c3ccncc3)nc2C)s1 +COC1CCCC1OC(=O)COc1ccc(C(C)=O)cc1 +C#CCOc1ccc(C(=O)N2CCN(CC(=O)C3CC3)CC2)cc1 +CC(C(=O)N(C)c1cccc(C#N)c1)c1cccs1 +CCOC(=O)Cn1nc(C)n(-c2ccccc2Cl)c1=O +CCN(Cc1ccccc1)C(=O)c1ccc(C)c(C)c1 +COC(=O)Cn1c(-n2ccnc2)nc2c1c(=O)n(C)c(=O)n2C +COC(=O)c1ccc2nc(NC(=O)c3nn(C)cc3C)sc2c1 +CCOc1ccccc1NC(=O)c1cccc(NC(C)=O)c1 +CCc1noc(CC)c1CC(=O)Nc1c(C)cccc1C(C)C +CCOc1nn(CC)cc1C(=O)NCCc1c[nH]c2ccccc12 +Cc1cc(C)n2nc(C(=O)Nc3cc(C)on3)nc2n1 +CCOC(=O)C(NC(C)C)c1cccc(Cl)c1 +Cc1ccccc1C(=O)Nc1ccc2nc[nH]c2c1 +O=C(NC1CCCC1)c1nc[nH]c1C(=O)NC1CCCCC1 +O=C(Cc1csc(Nc2ncccn2)n1)Nc1cccc(Cl)c1 +CCc1c(C(=O)Nc2cccnc2)cnn1-c1ccc(F)cc1 +O=C(NCc1cn[nH]c1)c1ccccc1C#CCO +Cc1nc(C)c(C(=O)OCc2ccc(C#N)cc2)s1 +O=C(COC(=O)c1ccsc1)NCc1ccccc1C(F)(F)F +Nc1c(-c2ccco2)nc2scc(-c3ccncc3)n12 +O=C(c1cc(N2CC3CC4CC(C3)CC2C4)ccn1)N1CCOCC1 +O=C1CC(c2ccco2)Cc2nc(NCC3CCCO3)ncc21 +CC(C)(C)OC(=O)N1CCN(C(=O)CCc2ccccc2F)CC1 +CCn1cc(N2Cc3nc(N4CCC(O)CC4)ncc3C2=O)cn1 +COc1cccc(C(=O)OC(C)C(=O)Nc2ccccc2)c1F +CCC(C)OC(=O)CCC(=O)Nc1ccc(C)cc1 +Cc1cccc(OCC(O)CN2CC(=O)Nc3ccccc32)c1 +CC(=O)c1ccc(NC(=O)Nc2cccc(F)c2)cc1 +CC(C)c1nccn1-c1ccc(C(C)(C)C(N)=O)cc1 +CN(Cc1ccccc1)C(=O)c1cn(-c2ccccc2)c2ncccc12 +CCS(=O)(=O)N1CCN(C(=O)c2cccnc2)C(C(=O)OC)C1 +Cn1c(=O)cc(OCCCC(=O)N2CCCCCC2)c2ccccc21 +O=C(Nc1cccc(N2CCCC2=O)c1)c1ccccc1-n1cccn1 +Cc1ccn2c(=O)c(C(=O)Nc3ccccn3)cnc2c1 +Cc1nc(N2CCCC(C(C)O)C2)ccc1Br +O=C(Cc1nc(-c2ccc(F)cc2)cs1)N1CCOCC1 +COC(=O)c1cc(S(=O)(=O)N2CCCCC2C)c[nH]1 +Cc1ccc(C)c(OCCC(=O)NC2CCC(O)CC2)c1 +CCC1CCc2c(sc(NC(=O)c3cc(C)on3)c2C#N)C1 +CC(=O)c1ccc(C(=O)N2CCCC2CC(=O)c2ccccc2)cc1 +C#Cc1cccc(N(C(=O)c2ccn(-c3ccccc3)n2)C(C)C)c1 +CCOC(=O)C(N)Cc1nc2c(s1)COCC2 +Cc1cccc2cnn(CCC(=O)Nc3ccn(C)n3)c12 +COc1ccc(Cn2cnc3c(N)c(C)c(C)cc32)cc1 +CC1CN(S(=O)(=O)CCNc2ccc(C#N)cn2)CC(C)O1 +CCOCc1cccc(NC(=O)c2ccncc2F)c1 +COc1cc2c(cc1OC)S(=O)(=O)N(CC(=O)C(C)(C)C)C2=O +Cc1cc(C(=O)NCC(=O)N(C)Cc2ccc(Cl)cc2)n(C)n1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)Nc1cc(F)cc(F)c1 +CN(Cc1ccccc1)C(=O)c1nc(-c2cccc3[nH]ccc23)no1 +CC(C)COc1ncc(CNC(=O)C2CCC(C)O2)cc1Cl +O=C(c1cc2c(s1)-c1ccccc1S(=O)(=O)C2)N1CCOCC1 +Cc1cccc(OCC(=O)Nc2cccc(N)c2C)c1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccc(F)c(Cl)c2)cc1 +O=C(CCOc1ccccc1)NC1CCc2ccccc21 +COc1ccc2nc(CCNC(=O)Nc3nncs3)[nH]c2c1 +O=C(CC1(O)C(=O)Nc2ccc(F)cc21)c1ccccc1 +CCCc1n[nH]cc1C(=O)NCCc1ccccn1 +CCOCC(=O)NCC1(O)CCc2ccccc2C1 +Cn1cnc(CNC(=O)NC2CCOC3(CCCCC3)C2)n1 +Nc1cc(C(=O)N2CCCC2)cc(C(=O)N2CCCC2)c1 +CCNC(=O)C1CCN(c2ccc3nnc(C(F)(F)F)n3n2)CC1 +COc1ccc(NC(=O)C2COc3ccc(F)cc3C2)cn1 +COC(CNC(=O)c1nc2nc(C)cc(C)n2n1)c1ccccc1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1cc(F)ccc1F +COc1ccc(C(=O)C(C)Oc2ccccc2N)c(OC)c1OC +Cc1nc(C)c(C(=O)Nc2cc(C(C)C)n[nH]2)s1 +COc1cccc(C2(NC(=O)CCn3nc(C)cc3C)CCCC2)c1 +COc1ccc(CN2CCN(C(=O)c3ncc[nH]3)CC2=O)cc1 +Cc1csc(C(C#N)C(=O)C(NC(=O)CC(C)C)C(C)C)n1 +CC(C)NC(=O)CCNS(=O)(=O)c1ccccc1Cl +COc1cc(F)c(C(C)NC(=O)c2ccccn2)cc1OC +COc1cccc(-c2ccc(C#N)c(=O)n2CC(C)C)c1 +CS(=O)(=O)c1ccc(-c2noc(COc3ccccc3F)n2)cc1 +CC(=O)N1CCCC1C(=O)c1cnn(-c2ccccc2)c1N +COc1ccccc1S(=O)(=O)Nc1ccccc1SC +C=CCNC(=O)CCC(O)c1ccc2c(c1)CCCC2 +O=C1Nc2cc(Br)ccc2OC12CCCC2 +COc1ccc(-c2cn3cccnc3n2)cc1NC(=O)C(C)C +Cc1cc(NC(=O)c2ccccc2)ncc1NC(=O)c1ccco1 +CC(=O)Nc1nnc(S(=O)(=O)N2CCCC2)s1 +O=C(Cc1ccc(F)cc1F)Nc1cc(-c2cccs2)n[nH]1 +CCc1nc(CCNC(=O)c2cccc(C#N)c2)sc1C +CN1C(=O)COc2ccc(NC(=O)Cc3ccc(F)c(F)c3)cc21 +CCn1c(=O)c(C(=O)Nc2cccc(C(C)=O)c2)nc2ccccc21 +COc1ccccc1NCCC(O)c1ccc(C)cc1 +O=C(C1CCCN1C(=O)c1cnc2[nH]ccc2c1)N1CCCC1 +Cc1cc(CN(C)S(=O)(=O)c2ccc(F)c(F)c2)no1 +CC(=O)Nc1ccc(S(=O)(=O)NCCCc2cccc(C)c2)cc1 +Cc1cccc(NC(=O)c2snnc2-c2ccccc2)n1 +O=c1cc(C(F)(F)F)oc2cc(F)cc(F)c12 +Cc1ccc(NC(=O)NCCS(=O)(=O)NCC2CCC2)c(F)c1 +CNC(=O)c1ccc(=O)n(Cc2ccccc2F)c1 +CNC(CC(=O)OC)C(=O)c1cc(C)ccc1OC +Cn1ncc2c1CCCC2NC(=O)c1cc(Cl)c[nH]1 +CCCN(CC(=O)OCC)C(=O)c1ccnc(F)c1 +CS(=O)(=O)c1cccc(NC(=O)Cc2noc3ccccc23)c1 +CS(=O)(=O)N1CCN(C(=O)c2ccc3c(c2)OCCO3)CC1 +Cc1cccc(NCC(=O)N2C(C)CCCC2C)c1 +CCC(=O)Nc1ccc(NS(=O)(=O)c2cc(C)ccc2O)cc1C +COCCNC(=O)N1CCN(CCn2c(C)nc3cccnc32)CC1 +COCCOCc1nc(C)nn1C1CCCCC1 +O=C(CSc1nnc2n1CCCCC2)c1c[nH]c2ccccc12 +CCc1nc(COC(=O)c2ccc(C(N)=O)cc2)cs1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)NCC#Cc1ccccc1 +CCc1nc(CSc2nnc(C)n2C)cs1 +CC(Sc1ccccn1)C(=O)NC1CCCCC1 +COc1cccc(CCC2CCCN(C(=O)c3cnc(C)cn3)C2)c1 +CC(C)(C)c1ncc2c(n1)CN(C(=O)c1scc3c1OCCO3)C2 +CCCCNC(=O)c1[nH]c(C)c(C(=O)OC)c1C +O=C(c1ccncc1)N1CC2CCN(c3cccnc3)CC2C1 +CCc1c(C)nc2n(c1=O)CC(C(=O)N1CCC(O)CC1)CS2 +CN(Cc1cccnc1)C1CN(S(C)(=O)=O)C2CCCOC12 +CN(Cc1nccn1C(F)F)C(=O)c1ccc(C#N)cc1 +O=C(c1ccc2[nH]ncc2c1)N1CCC(Oc2cccc(Cl)c2)C1 +O=S(O)c1cccc2c(S(=O)O)cccc12 +CN(C)c1ccc(-c2noc(CCNC(=O)CC(C)(C)C)n2)cc1 +CC(C)(C)NC(=O)C1CCCCN1c1nccc(C(F)(F)F)n1 +Cc1c(C(=O)OC(C)C(=O)NCC2CCCCC2)cnn1C +CCCOn1c(OCC(C)C)nc2ccccc2c1=O +COc1ccc(CN(C)Cc2cc(C(F)(F)F)ccc2F)cc1O +Cc1cc(NC(=O)c2n[nH]c3ccc(Br)cc23)[nH]n1 +CCn1c(SCC(=O)c2ccc(F)cc2)nc2cccnc21 +Cc1ccc(N2CC(c3nc4ccccc4[nH]3)CC2=O)c(C)c1 +CCNC(=O)NC1(C(=O)N(C)Cc2ccccc2Cl)CCCC1 +CC(C)N(C1CCC1)S(=O)(=O)c1ccc2[nH]c(=O)[nH]c(=O)c2c1 +COc1cccc(CC(=O)NCc2cnn(Cc3ccccc3)c2)c1 +COc1cccc(CN(C)C(=O)CSc2nc3ccccc3o2)c1 +CN(C)c1ccccc1NC(=O)c1ccc(-n2ccnn2)cc1 +CCNS(=O)(=O)c1ccc(C)c(C(=O)Nc2ccccc2C)c1 +COCCOC(=O)Nc1cccc(NC(=O)c2cc(F)ccc2C)c1 +CCSc1nnc(NC(=O)Cc2cc(Cl)ccc2OC)s1 +c1ccc2c(c1)CCC2Nc1ncnc2ccccc12 +CCCOc1cccc(NC(=O)Cc2c(C)nc(C)[nH]c2=O)c1 +Cn1ncc2c(N3CCN(S(C)(=O)=O)CC3)ncnc21 +Cc1nn(C)c2ncc(SCC(O)COC(C)C)cc12 +O=C(Oc1ccc2c(c1)CCC2)C1CCN(C(=O)c2ccoc2)CC1 +Cc1ccc(C(=O)N2CCCC2Cn2cccn2)cc1S(N)(=O)=O +CC(C)OCc1cccc(S(=O)(=O)NC2CCCC2)c1 +Cc1noc(C)c1C(C)NC(=O)C1CC1c1cccc(Cl)c1 +Cc1noc2ncc(C(=O)NCc3ccoc3)cc12 +CC(NS(=O)(=O)N(C)C)c1ccc(-c2ccccc2)cc1 +CN(C)S(=O)(=O)c1cccc(COc2cccc(F)c2)c1 +CCn1cc(NC(=O)C2CCN(Cc3nc(C)c(C)s3)CC2)cn1 +COCC(NC(=O)C1(Cc2cccc(Cl)c2)CCCC1)C(N)=O +COC(=O)Cc1ccc(OCc2noc(-c3cccs3)n2)cc1 +Cc1nn(C)c2c(N3CCCCC3C)nc(C3CC3)nc12 +Cc1cc(C(C)NC(=O)NC(C)C(=O)NCc2ccco2)c(C)o1 +Fc1ccc(CSc2nc(C3CC3)n[nH]2)c(Br)c1 +Cc1cccn2cc(C(=O)N3CCC(C)CC3)nc12 +C#CCOC(=O)c1ccc(NC(C)=O)c(SC)c1 +COC(=O)c1ccc(C)c(S(=O)(=O)N(C)CCC(F)(F)F)c1 +O=C(CNC(=O)c1ccco1)OCc1ccccc1F +CCC(C)C(C)NC(=O)CCc1ccc(C#N)cc1 +CC(=O)N1CCCc2cc(NC(=O)c3cccc(Cl)c3)ccc21 +CC(=O)Nc1ccc(C(=O)N(CCCO)C(C)C)s1 +CCOc1ccc(NC(=O)c2ccc(=O)n(C)c2)cc1Cl +O=C1c2cnc(N3CCCC3)nc2CN1Cc1cccc(F)c1 +CC=CCOC(=O)c1nn(CC(C)C)c(=O)c2ccccc12 +Cc1cccc(CN2C(=O)CC3C2CCN3C(=O)NC2CCCC2)n1 +O=C(c1ccccc1)C1NCCc2cc3c(cc21)OCC3 +CN1C(=O)CC(C(=O)N2CCNC(=O)C2)C1c1cccnc1 +Cc1occc1C(=O)N1CCOCC2(CC(Cn3cnnc3)CO2)C1 +CC(=O)NC1CCCN(C(=O)NCc2ccoc2)C1 +CC(=O)NC1CCN(C(=O)c2cccc3ccc(C)nc23)CC1 +CC1CN(C(=O)NCc2ccc(O)cc2)c2ccccc21 +CCc1ccccc1OCCCN(C)C(=O)c1cnc(C)nc1C +COC(=O)C(C)CN(C)C(=O)c1cc(C(C)=O)c[nH]1 +COC(=O)c1ncn(CCOC2CCCCCC2)n1 +O=C(NCCCN1CCCC1=O)c1cc2cc(F)ccc2[nH]1 +Cc1ccc(CC(=O)N(Cc2ccco2)Cc2cccs2)cn1 +CCC(CC)NC(=O)N(C)Cc1csc(C)n1 +Cc1cccc(Oc2ncnc3c2cnn3C)c1C +CCN1CCc2nc(NC(=O)c3cc(C(N)=O)cs3)sc2C1 +NC(=O)c1ccc(-c2nnn(Cc3c(F)cccc3Cl)n2)cc1 +Cc1cc(NC(=O)C(OC(=O)c2ccc3c(c2)OCO3)C(C)C)no1 +CCc1ccc(N2CCN(C(=O)c3cccnc3)CC2)cc1N +COC(=O)CCCCNC(=O)C1(C#N)CCCC1 +Cc1c(C(=O)NCCc2nc3ccccc3[nH]2)cnn1-c1ccccc1 +Cc1nc(CCNC(=O)c2ccc(C(F)(F)F)nc2)cs1 +O=C(NCCN1CCN(c2ccc(F)cc2)CC1)C1CCCC1 +COc1cc2nc(NC(=O)c3ccnn3C(C)C)sc2cc1OC +O=S(=O)(CC1CCCCC1)c1nccn1C1CC1 +CCC(=O)N1CCOC(c2cccc(OC(F)F)c2)C1 +O=C(C1CCCN1C(=O)c1ccco1)N1CCCCCC1 +NC(c1ccccc1)c1nc2cccnc2n1C1CCCC1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)Nc3ccnc4ccnn34)c12 +N#Cc1ccc(NCc2ccc(C#N)cc2F)cc1 +CC(=O)OC(C(=O)Nc1nc2ccccc2s1)c1ccccc1 +COc1ccc(CNC(=O)NCC#Cc2ccccc2N(C)C)cc1 +O=C1CCCN1CC(O)CNc1ccc2nnc(C(F)(F)F)n2n1 +CC(=O)N(C)Cc1cccc(NC(=O)NC(C)C(=O)NC(C)(C)C)c1 +CCNS(=O)(=O)C1CCN(c2ccc(C#N)nc2)C1 +NC(=O)c1nnn(-c2cccc(C(F)(F)F)c2)c1N +CCc1ccccc1N1CC(C(=O)N(CC)CCO)CC1=O +CCN1C(=O)C=C(c2ccco2)Nc2ccc(C)cc21 +CN(C(=O)c1ccno1)c1nnc(-c2ccccn2)s1 +O=C(Nc1cccc(Cn2ccnc2)c1)c1cc2ccccn2n1 +CSc1nnc(SC(C)C(=O)NCCC(C)C)s1 +CCCNC(=O)c1ccc(-n2nnc3cccnc32)cc1 +Cn1cnc(CNC(=O)NC2CC2c2cccc(Cl)c2)n1 +CC(=O)Nc1cccc(COC(=O)c2ccc(C(=O)N(C)C)cc2)c1 +O=C(NCCOc1cccnc1)C1CCc2ccccc2O1 +CCSc1ccc(-c2cccc(NC(=O)C3CCCO3)c2)nn1 +CC(C)CN(C)C(=O)C1CCN(C(=O)NC(C)C)CC1 +COc1ccc(C(=O)CC2(O)C(=O)N(C)c3ccccc32)cc1 +COC(=O)c1nn(-c2cccc(Cl)c2)c2c(=O)[nH]cnc12 +Cc1nnc(COc2nc(Cc3ccc(F)cc3)no2)o1 +Cc1cc(NC(=O)NCC(C)(C)C(N)=O)ccc1C(=O)NC(C)C +CC(C)Cn1ncc(C(=O)C(C#N)c2ccc(F)cn2)c1C1CC1 +COC(=O)C1=C(C)N(C)C(=O)CC1c1cccc(F)c1 +CCc1ccc(N2CC(C(=O)OCc3cc(C)on3)CC2=O)cc1 +CC(=O)c1ccc(NC(=O)CSc2nnc(C)s2)cc1 +CCOc1ccccc1-n1c(C)cc2c(cnc3ncnn32)c1=O +Cc1nc2sc3c(c2c(=O)n1NC(=O)c1ccn(C)n1)CCCC3 +O=C1NC2(CCc3ccccc32)Nc2ccccc21 +CC(C)c1ccccc1NCC(=O)NCC(F)(F)F +Cc1cccc(C)c1OCC(=O)Nc1c(C(N)=O)oc2ccccc12 +C=CCCCN(C)C(=O)c1cc(-c2csc(C)n2)c[nH]1 +Cc1cc(C)c(CNC(=O)c2nn(C)c(=O)c3ccccc23)c(=O)[nH]1 +CCOc1ccc(C(=O)Nc2c(C)nc3cc(C)ccn3c2=O)cc1 +Cc1noc(C2CCCN2C(=O)Nc2c(F)cccc2F)n1 +CCS(=O)(=O)N(CCO)c1ccc(C)c(Cl)c1 +COc1ccc2c(c1)CCCN2C(=O)NCCCOCC1CCCO1 +CCC(CC)N(CCO)c1ncc(CO)cc1Cl +COc1cc2oc(=O)ccc2cc1C(=O)CC(C)C +Cc1nc(C2(NC(=O)c3cccc(F)c3)CCCCC2)no1 +CNc1snc(C)c1C(=O)N(C)Cc1ccc(F)c(F)c1 +COc1ccc(Cc2nnc(NC(=O)Cc3cccc(C)c3)o2)cc1 +Nc1ccc2oc(C(=O)NCc3ccccc3)cc(=O)c2c1 +Cn1ccnc1C(=O)c1ccc2c(c1)C(C)(C)C(=O)N2 +Cc1cnn(CC2CCCCN2C(=O)CCNS(C)(=O)=O)c1 +O=C(NCc1ccccc1F)C1CCCN(C(=O)NC2CC2)C1 +CC(C)C(NC(=O)Nc1cn[nH]c1)c1ccc2c(c1)OCCCO2 +CCNC(=O)c1cccc(NC(=O)CNc2c(C)cc(C)cc2C)c1 +CC(=O)NC1C(OC(=O)c2ccccc2)OC(CO)C(O)C1O +CC(C)CC1COCCN1C(=O)Cc1cc2ccccc2[nH]c1=O +COC(=O)c1ccc(NC(=O)c2c(F)cccc2F)cc1 +COc1ccc(C(=O)N(CC(F)(F)F)C2CCOCC2)c(OC)c1 +Nc1ccc(F)c2ccnc(C(=O)NCc3cccnc3)c12 +CCCCC1(C)Nc2ccccc2C(=O)N1CC1CCCO1 +CCNC(=O)c1ccc(C)c(NCc2cn3cc(Cl)ccc3n2)c1 +O=C(NCc1nnc2n1CCCCC2)C1CC=CC1 +CC(C)n1cnc2cc(CNC(=O)Cc3c[nH]c4ccccc34)ccc21 +COc1ccc(CNC(=O)Nc2ccc(OC)c(C)c2)c(OC)c1 +Cc1cccnc1CN(C)c1nc(C2CCCC2)nc2c1cnn2C +CC(NC(=O)c1cccc(-n2cnnn2)c1)C1CC1 +CC1CN(C(=O)c2cc(OCC3CC3)c3ccccc3n2)CCO1 +COc1ccc(C)cc1NC(=O)CSc1nc(C(C)(C)C)n[nH]1 +CCN(CC)C(=O)CNc1cccc(NC(=O)OC)c1 +CCN(CCNC(=O)c1cnc(C)cn1)c1cccc(C)c1 +O=C(c1cccc(F)c1)N1CCCC1c1nc(-c2ccccc2)n[nH]1 +COc1ccc2[nH]cc(C3CCCC(NC(=O)C4CCCO4)C3)c2c1 +Cc1nc(C(=O)Nc2cccc(CO)c2)ccc1C#N +CC(=O)N(C)CC(=O)Nc1cc(-c2ccccc2)nn1-c1ccccc1 +Cc1cccc(C(=O)Nc2nnc(SCC(=O)NC3CC3)s2)c1 +CNC(=O)c1cc(C)ccc1NC(=O)c1ccco1 +CC(C(=O)NC1CCCC1)N(C)Cc1nc2ccccc2c(=O)[nH]1 +CCCCNC(=O)C(C)(C)CS(=O)(=O)N1CCNCC1 +CC(C)(C)OC(=O)N1CCC(CNC(=O)c2cccs2)C1 +Cc1csc(NC(=O)CSc2nc(=O)[nH]c3c2CCCC3)n1 +O=C(Nc1cccc(C(F)(F)F)c1)c1ncn(-c2ccccc2)n1 +COC(=O)Cc1c(C)nc(SCCCO)[nH]c1=O +CCc1nc2ccccc2n1Cc1ccnc(N)c1 +O=C(NCCCC1CCCC1)N1CCN(C(=O)C2CCCO2)CC1 +O=C(c1cccnc1)N1CCN(c2cc(NCC3CC3)ncn2)CC1 +Cc1cc(NC(=O)c2oc3c(C)ccc(C)c3c2C)n(CCC#N)n1 +CCOc1ncnc(NCCc2c[nH]c3ccccc23)c1N +O=C(c1ccc2cc[nH]c2c1)N1CCCC1c1nc(C2CC2)no1 +O=C(Cn1cncn1)NCc1ccccc1Sc1ccccc1 +COc1cc(CNC(=O)c2cnn(C)c2)ccc1OCC(N)=O +Nc1cc(Cl)c(Br)c(C(F)(F)F)c1 +COC(=O)C(NC(=O)c1ccc(Cl)c(N)c1)C(C)C +CCN(C(=O)C1CN(C(=O)c2cc(C)on2)C1)C1CCCCC1 +CCc1nnc2n1CCN(c1ncnc3c1CCC3)C2 +CCOC(=O)c1cc(-c2ccc(OCC)c(N)c2)nn1C +CC(NC(N)=O)C(=O)NCCCSc1ccccc1 +Cc1ccc(C)c(NCC(=O)N2CCN(S(C)(=O)=O)CC2)c1 +CC(C)NC(=O)CNC(=O)CN(C)c1ccccc1 +Cc1cccc(NC(=O)c2[nH]nc(C)c2Br)n1 +Cc1ccc(F)c(NC(=O)NCC(=O)Nc2ccccc2)c1 +Cc1cc(C(=O)Nc2nnc(-c3ccnn3C)o2)n(C)n1 +Cc1ccc(S(=O)(=O)Cc2cc(=O)n3ccccc3n2)cc1 +CC(=O)Nc1ccc(O)c(C(=O)NC2c3ccccc3CC2O)c1 +O=C1Cc2ccccc2C(c2ccc(Br)cc2)N1 +COc1ccc(CNC(=O)Nc2nnc3ccccn23)cc1 +Cc1cc(C2CCCN2C(=O)Nc2ccccc2F)on1 +CNC(=O)c1ccc(NC(=O)C2(C)Cc3ccccc3C(=O)O2)cc1 +O=C(c1ccc(=O)[nH]c1)N1CCCSc2ccccc21 +Cc1ccc(N(C)C(=O)C(C(C)C)N2CCCC2=O)cc1 +O=S(=O)(Cc1ccccc1Cl)c1nnc(N2CCCC2)s1 +CC(O)CNC(=O)CN(C)C(=O)c1cccs1 +NC(=O)c1ccc(NC(=O)c2ccco2)cc1Cl +O=C(Cc1cccc(CNC(=O)c2cc3cccnn3n2)c1)NC1CC1 +CCC(C)NC(=O)c1ccc(N2CCCS2(=O)=O)cc1 +Cn1cc(-c2nc(C(=O)NCCC3CCCO3)cs2)cn1 +Cc1cc(Br)cc(C)c1NC(=O)NCCC(=O)N(C)C +O=C1CN(C(=O)Cn2ccc(C(F)(F)F)n2)c2ccccc2N1 +Cc1nc(COc2ccccc2C(=O)NC(C)c2ccncc2)no1 +Cc1nc(C(=O)N2CCC(C)CC2C)nn1-c1ccccc1C(C)C +CC(C)COC(=O)Nc1cccc(NC(=O)Cc2ccc[nH]2)c1 +COC(=O)c1ncn(Cc2ccc(Br)cc2F)n1 +O=C(NC1CC(=O)N(c2ccc(F)cc2)C1)N1CCCCCC1 +CC(NC(=O)Nc1ccccc1)C(=O)Nc1cccc(-c2cn[nH]c2)c1 +c1cncc(-c2nc(-c3ccc4c(c3)OCO4)cs2)c1 +Cc1cnc2c(c1)nc(C(Cl)(Cl)Cl)n2CCCO +COc1ccc(OC)c2c1CCNC2c1cccc(C)n1 +Cc1occc1C(=O)Nc1cc(Cl)ccc1C(N)=O +O=C(CCCc1c[nH]c2ccccc12)Nc1nnc(C2CC2)s1 +Cc1ccc2cccc(OCC(=O)NCc3ccccc3)c2n1 +CCc1nc(C)c(C(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)s1 +C=CCN1CCOC2CCN(C(=O)c3nc[nH]n3)CCC21 +O=C(COc1ccc(F)cc1)NCc1nc(-c2cccs2)no1 +CC1CN(Cc2ccnn2C)CC(c2ccccc2)O1 +Cc1ccc(Cl)c(OCc2cc(=O)n(C)c(=O)n2C)c1 +Cc1n[nH]c(C2CN(C(=O)COC3CCCC3)CCO2)n1 +CC(C)c1nc(CN(C)C(=O)c2sccc2Cl)cs1 +CC(C)(C)C(=O)N1CCCC(c2nnc(Cc3ccc(F)cc3)o2)C1 +Cc1ccc(NC(=O)N2CCC3CCCCC32)cc1S(C)(=O)=O +O=C(NC1CCN(C(=O)c2ccco2)CC1)C1CC1 +CC1=CC(C)(C)N(C(=O)c2ccco2)c2ccc(O)cc21 +COc1ccc(F)cc1C(=O)NCc1cnn(Cc2ccccc2)c1 +CCCc1n[nH]c(C2CN(C(=O)Cc3csc(CC)n3)CCO2)n1 +C=CCC1(CO)CCCN(c2cc(N3CCCC3)nc(N)n2)C1 +COc1cccc(C(=O)N2CC(OCc3ccc(Cl)cc3)C2)c1 +Cc1ccc(CC2CN(CCO)c3ccc(O)cc3O2)cc1C +CC1(C)CC1(C(=O)Nn1cnnc1)c1cccs1 +Nc1nccnc1C(=O)Nc1ccc2nc(N3CCCC3)sc2c1 +Brc1cn[nH]c1-c1nn2c(-c3ccccc3)nnc2s1 +CC(=O)c1csc(NC(=O)COc2ccccc2C(F)(F)F)n1 +COc1ccc(Cl)cc1NC(=O)c1csc(C)n1 +CC(NC(=O)CCc1ccccc1)c1nnc2ccccn12 +NC(=O)c1cnc(NC(=O)c2occc2COc2ccccc2)s1 +COc1ccc2cc(C(=O)N(C)Cc3cnn(C)c3)[nH]c2c1 +C#CCN1CCN(Cc2nc(C(C)(C)C)cs2)CC1 +O=S(=O)(CCNCc1c(F)cccc1F)N1CCOCC1 +CCOC(=O)NC(C(=O)N1CCN(c2nccs2)CC1)C(C)C +CC1CCN(c2nc(CNC(=O)c3cccnc3)cc(=O)[nH]2)CC1 +CCCN1C(=O)C(O)(CC(=O)c2ccc(C)o2)c2cc(Cl)ccc21 +CC(Nc1cccc(Oc2ccccc2)c1)C(=O)N(C)CCC#N +CSc1cc(NC(=O)N2CCCCC2c2cn[nH]c2)ccn1 +Cc1cccc(NC(=O)Cc2noc(-c3cc(C#N)cn3C)n2)c1C +CCCn1cnnc1Cn1ccnc1-c1ccc2occc2c1 +CC(Oc1ccc2c(c1)OCO2)C(=O)NCCCn1ncccc1=O +COc1ccc(Cl)cc1S(=O)(=O)Nc1ccccc1 +CN(Cc1cnn(C)c1)C(=O)Cn1c(=O)n(C)c2ccccc21 +Nc1nccnc1C(=O)NCc1ccc(Br)cc1Cl +Cc1cc(C(=O)NC2CCN(C(=O)C(C)C)CC2)c(C)s1 +C#CCOC(=O)C1CCN(S(=O)(=O)c2ccc(C)cc2C)CC1 +CC(OCC1CC1)C(=O)NCCC(=O)N1CCCc2ccccc21 +Fc1cc(F)c(CN(CC(F)F)C2CC2)cc1F +COC(=O)Cc1csc(NC(=O)c2cc(F)cc3[nH]cnc23)n1 +Cn1nc(C2CC2)nc1-c1ccc(F)c(Br)c1 +COc1ccc(C(CC(=O)Oc2cccc(C)c2C)NC(C)=O)cc1 +CN(C(=O)CCn1cccn1)c1ccc2c(c1)OCO2 +COc1cccc(CNC(=O)Nc2cccs2)c1OC +O=C(Nc1ccccc1-c1nc(-c2ccccc2)n[nH]1)c1ccoc1 +Cc1cc(C)n2nc(SCc3ccccc3F)nc2n1 +CC(NC(=O)N1CCOC(C)(C)C1)c1ccc(-n2ccnc2)cc1 +CC(=O)Nc1ccc(C(=O)N(C)C2CCCCCC2)cc1 +CC(C)C(c1ccoc1)S(=O)(=O)c1ccccc1 +CC(=O)Nc1cccc(NS(=O)(=O)c2cccs2)c1 +COc1cccc(CNC(=O)Nc2ccc(OC)c3ncccc23)c1 +CN(Cc1cscn1)c1nc2sccn2c1CO +COc1ccc(NC(C)=O)cc1NC(=O)NCC1CCCC(C)C1 +CCn1nc(C)c(CNc2nc3nonc3nc2N(C)C)c1C +C#Cc1cccc(NC(=O)CNC(=O)c2sc(C)cc2OC)c1 +Cn1ncc(C(=O)OCc2nc3ccccc3s2)c1-n1cccc1 +CC(Sc1ncccc1Cl)C(=O)NC1CCCC1 +O=c1ccc2cccc(OCc3ccccc3F)c2[nH]1 +Cc1nn(-c2ccccc2)c(C)c1NC(=O)c1cccs1 +O=C(Cn1nc(C(=O)N2CCCC2)c2ccccc21)Nc1ccccc1 +N#Cc1ccc(C(=O)Nc2ccccc2OC(F)F)c(F)c1 +CCC(C(=O)NCCC(O)c1cc(C)oc1C)c1ccccc1 +COc1cc(COC(=O)CCn2c(=O)oc3ccccc32)ccc1C +O=C(c1cccs1)N1CC2OCCN(c3cccnc3)C2C1 +Cc1cc(NC(=O)c2cc3cccc(Cl)c3s2)nn1C +CN(C)C(=O)Cn1cc(C(=O)N(C)Cc2cccnc2)nn1 +CN(CC(=O)NC1CC1)C(=O)CNc1ccc2c3c(cccc13)CC2 +CCOc1c(OC)c(Cl)cc2c1C(C(C)(C)O)NCC2 +O=C(N=c1[nH]cn[nH]1)C1CCCN1C(=O)C1CCCCC1 +CC(C)Cc1nnc(NC(=O)CSc2ccccc2)s1 +O=C(CSc1cc(Cl)ccc1Cl)NC1CC1 +Nc1ccc2c(N3CCCC(c4nccs4)C3)ncnc2n1 +COc1cc(OC)cc(C(=O)OCCc2scnc2C)c1 +O=C(NCC(c1cccs1)N1CCCC1)c1cccnc1 +CNC(=O)C1CCCN(Cc2cnc(C(C)C)s2)C1 +COC(=O)c1cc(-c2cc(C)cc(C)c2OC)n[nH]1 +NC(=O)C(NCCOc1cccc2ccccc12)c1ccccc1 +CCc1ccc(-c2cnnc(N)c2C(=O)N2CCCCC2)cc1 +CCOc1ccc(NC(=O)c2ccc[nH]2)cc1S(=O)(=O)N(C)C +Cc1nc(CS(=O)(=O)c2nnc(NC3CCCCC3)s2)no1 +Cc1cccc(C(N)C(=O)NCC2CCCO2)c1F +COc1ccccc1-c1cc(C)nc2onc(N)c12 +CN(C)C(=O)COc1cccc(NC(=O)C2CC3CCC2O3)c1 +O=C1CCc2cc(NC(=O)c3cnc4sccn4c3=O)ccc2N1 +CC(C)NC(=O)COC(=O)c1ccccc1OC(F)F +N#Cc1cccnc1NCc1ccc(Cn2cncn2)cc1 +NC(=O)c1ccc(N2CCCC2)c(NC(=O)c2ccc(Cl)cc2)c1 +Cc1c(N)cccc1NC(=O)CCN1CCOC(C)C1 +CCCc1c(C)nc2ncnn2c1Sc1ccc(N)cc1 +CCn1cc(C(=O)N2CCN(S(C)(=O)=O)CC2)c2ccccc21 +CN(C)C(=O)c1cc(NC(=O)C(C)(C)c2cccc(Cl)c2)ccn1 +CC1CCCC(NC(=O)NCc2cn(-c3ccccc3)nn2)C1 +O=C(c1c(-c2ccccc2)nn2ccccc12)N1CCOCC1 +Cc1ccc2c(c1)CCN2C(=O)NC1CCN(S(C)(=O)=O)CC1 +COc1ccccc1S(=O)(=O)N(C)Cc1ccccc1Cl +O=C(NC1CCCc2ccccc21)c1nc2ccccc2c(=O)[nH]1 +CCN(C)c1ccc(C(=O)N(C)c2ccc(Cl)cn2)cc1 +CCc1nc(CC(=O)N2CCC(Nc3ccccc3)CC2)cs1 +CN(CC1CCCCO1)C(=O)NC1CCC(O)CC1 +c1coc(-c2nc(CCn3cnc4ccccc43)no2)c1 +NC(=O)c1ccc(OC(=O)c2ccc3ccccc3n2)cc1 +C=CCOc1ccc(C(=O)N(C)Cc2cc(C)on2)cc1OC +Clc1ccc(CCc2nc(-c3ccncc3)no2)cc1 +Cc1cc(NC(=O)NC(C)(C)c2nc(C)c(C)s2)no1 +CCC(C)(C)NC(=O)C(C)Sc1nnnn1Cc1cccs1 +COc1ccc(C(=O)Nc2cccc(NC(=O)NC(C)C)c2)cc1F +COC(=O)c1cc(=O)n2c(nc3cc(OC)ccc32)s1 +CC(C)Sc1nc(-c2ccco2)nc2c1c(=O)n(C)c(=O)n2C +C=CCC1(CC=C)CCCN1C(=O)c1cccc(NC(=O)CC)c1 +CC(C)n1ncc2ccc(NC(=O)c3ccncc3)cc21 +COCC(=O)N(C)CC(=O)Nc1cnc2[nH]nc(C)c2c1 +Cc1nc(CNC(=O)N2CCC(C)CC2C)oc1C +CC(C)OCCNC(=O)NCc1cc(=O)[nH]c2ccccc12 +COc1cc(O)c2c(c1)C(c1cccc(C)n1)NCC2 +CC(=O)Nc1cc(CCC2CCCN(c3ncccn3)C2)ccn1 +Cc1cc(NC(=O)c2cccnc2OCC(F)F)ccc1C(N)=O +Cn1cccc1C(=O)Nc1nc(-c2cccs2)cs1 +CSc1ccc(COc2ccccc2NC(C)=O)cc1 +CC(C)(C)C1CCC(C(=O)NCC(C)(C)N2CCOCC2)CC1 +CSc1nccc(Oc2cncc(Cl)c2)n1 +COC(=O)CC(NC(=O)Nc1ccccc1Cl)C1CC1 +Cc1ccc(N2CCCC2=O)c(C(=O)NC(C)c2cc(C)oc2C)c1 +CC1CC1C(=O)N(C)CC(=O)Nc1cccc(F)c1 +Cc1ccc(NC(=O)CS(=O)(=O)c2nnc(C3CC3)n2C)cc1 +O=C(c1ccc(-c2cncnc2)nc1)N1CCN(c2ccccc2)CC1 +Cc1cc(C)c(NC(=O)CSc2nnc(C(C)(C)C)n2N)c(C)c1 +Cc1cccnc1NC(=O)Nc1ccc(N2CCCS2(=O)=O)cc1 +CCn1c(SCc2ccc(F)cc2)nc2c1c(=O)n(C)c(=O)n2C +COC(=O)c1cc(-c2c[nH]c(=O)[nH]c2=O)cs1 +O=C(NC12CC3CC(CC(C3)C1)C2)C1CN(C(=O)c2cnccn2)C1 +Cc1noc(C)c1CC(=O)OCc1cc(=O)n2cc(Cl)ccc2n1 +CCOC(=O)N1CCC(NC(=O)CCCc2cccs2)CC1 +CCOC(=O)c1ccc(-n2nnc(CO)c2COC)cc1 +Nc1ccnc(CNC(=O)CCCn2ccc3cc(Cl)ccc32)n1 +O=C(COc1ccccc1F)NCC1(O)CCc2ccccc2C1 +COCCNc1ncnc(Nc2ccc(C)cc2)c1N +COc1ccc2nc(NC(=O)Cc3ccc(C)nc3)sc2c1 +Cc1nn(C)c(C)c1CCC(=O)NCc1ccnc(OC2CCC2)c1 +Cc1nc2ccccc2nc1SC(C(=O)N1CCOCC1)C(C)C +COCC1CCCN(C(=O)c2cccc(-n3cnnn3)c2)C1 +O=C(COc1ccc(N2CCCC2=O)cc1)Nc1nccs1 +N#Cc1ccc(-c2noc(C3Cc4cc(F)ccc4O3)n2)nc1 +CNC(=O)c1cc(C)c(C)c(S(=O)(=O)NC)c1 +O=C1CCc2cc(C(=O)NCC(=O)c3ccco3)c(F)cc2N1 +COc1ccc(C(C#N)N(C)C(=O)c2cccnc2)c(OC)c1 +COc1cc(C(=O)OCC(N)=O)cc2c1OCCO2 +Cc1ccoc1C(=O)NCc1cccc(NC(C)C)c1 +COCc1csc(NC(=O)N2CCN(c3ccccc3)CC2)n1 +O=C(c1cnc(-c2ccccc2)nc1)N1CCCC1Cc1ccccc1 +CNC(=O)C(C)NC(=O)C1CCCN(C(=O)C(C)(C)C)C1 +CNC(=O)C(CC(C)C)NC(=O)Cc1nn(C)c(=O)c2ccccc12 +COC(=O)c1ccc(C2CC(C)c3nc(N)nn3C2)cc1 +Cc1ccn2c(=NC(=O)C3CCCN3C(=O)C3CCCC3)[nH]nc2c1 +N#Cc1ccc(NC(=O)NCc2ccc(N3CCCCC3=O)cc2)cc1 +CCC(Oc1ccccc1N)C(=O)c1ccc2c(c1)OCCO2 +COC(=O)CSc1ncccc1-c1nc2ccccc2[nH]1 +Cc1cccc(-c2nnc(SC3CCOC3=O)o2)c1 +COc1ccc(C(=O)OCC(=O)NC2CCCC2)cc1F +COc1ccc(NC(=O)C2(n3cnnn3)CCCCC2)cc1OC +Cc1ccc(C(=O)Nc2cc[nH]n2)cc1NC(=O)c1ccccc1F +CCS(=O)(=O)N1CCN(C(=O)CC(C)(C)C)CC1 +CC(=O)c1cc(C2OC(=O)c3ccccc32)c(O)cc1O +NC(=O)C1CCN(C(=O)CC(F)(F)F)c2ccccc21 +NC(C(=O)N1CCC(OCc2ccccc2)CC1)c1ccccc1 +CC(=O)Nc1ccc(NCc2ccc(F)c(C)c2)cc1 +COCC(=O)N1CCN(C(=O)c2ccc(=O)n(C)c2)CC1 +CNC(=O)c1ccc(NC(=O)NC2C=CCCC2)c(Cl)c1 +CCOc1c(C=C2Sc3cc4c(cc3N2C)OCO4)c(=O)c1=O +CC(=O)Nc1cccc(-n2nnc(SCc3ccccc3)n2)c1 +Cc1ccc(OCC(=O)N2CCc3ccc(N)cc3C2)cc1 +CCc1nc(C)sc1C(=O)Nc1ccc(Cn2cncn2)cc1 +CCC(C)(NC(=O)C1COc2ccc(F)cc2C1)c1nccs1 +CCOC(=O)C1=C(CC)NC(=O)NC1c1ccc(F)cc1 +COC(=O)c1cccc(C(=O)NCCC2CC3CCC2C3)n1 +O=C1CCCN1c1ccc(S(=O)(=O)N2CCCCC2)cc1 +CC(C)(C)c1csc(CNC(=O)N2CCOCC2C2CC2)n1 +O=C(NCc1cscn1)N(Cc1cccc(F)c1)C1CC1 +CCCC1CN(C(=O)Nc2cc(CCOC)nn2C)CCO1 +COC(=O)c1cc(-c2ccc(OC)cc2C)nc(N(C)C)n1 +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)NCCn1cccn1)O2 +O=C(CSc1ncc2ccccn12)NCCOc1ccc(F)cc1 +CCN(Cc1cccc(C)c1)C(=O)c1ccc2c(c1)OCC(=O)N2 +CC(C)NS(=O)(=O)c1ccc(C(=O)N2CCCC2)cc1 +CCCN1C(=O)CCC2CN(C(=O)CCn3cncn3)CCC21 +Cc1cc(=O)c(C(=O)N(C)CC(N)=O)nn1-c1ccc(Cl)cc1 +Cc1nc(NC(=O)COCC(F)(F)F)ccc1Br +CC(=O)N(C)c1ccc(NC(=O)CCc2ccc3c(c2)OCO3)cc1 +Cc1cc(C(=O)NCCc2cccs2)c(C)n1C(C)C +CCOc1cccc(C(C#N)N(C)C(=O)C(C)(C)C)c1 +O=C(c1ccc(Cn2ccnc2)cc1)N1CCCC1Cn1cccn1 +Cn1cc(CNc2cccc(OC(F)F)c2)nn1 +COc1ccc(C2CC2C(=O)NCCc2ccccc2OC)cc1 +CC(C)C(Sc1ccc(F)cc1)C(=O)NCc1ccco1 +Cc1occc1C(=O)NCC(=O)NCc1ccnc(OC2CCC2)c1 +CCOc1ccc(C2=CCN(C(=O)C(C)C)CC2)cc1 +COc1cccc(OCC(=O)N2CC(=O)Nc3ccccc32)c1 +CN1C(=O)CC(C(=O)NCC2CCC2)C1c1cccc(F)c1 +CCCCN(C)C(=O)c1onc(S(=O)(=O)CC)c1N +Cc1ccc(C(=O)CCC(=O)NC2CCCCC2C)s1 +O=C(OCC(=O)N1CCCCC1)c1csc(-c2ccccc2)n1 +CCc1ccc(NC(=O)CSc2noc(-c3ccncc3)n2)cc1 +O=C(NCCO)NC(c1ccccc1)c1ccccn1 +COc1cccc(OCC(=O)Nc2cccc(C)n2)c1 +N#CCCNC(=O)CNc1ccccc1SC(F)F +COCc1cccc(NC(=O)c2cc(C)nc(SC)n2)c1 +CCCNC(=O)c1cccc(C(=O)Nc2cccc(-c3ncc[nH]3)c2)c1 +CC(=O)C(C)n1c(S(=O)(=O)Cc2ccccc2)nc2ccccc21 +Cc1cc(C)n(CCCNC(=O)CC(C)(C)C)n1 +O=C(Cc1ccc(Cl)cc1)Nc1ccc(CN2CCCC2=O)cc1 +CCC(C)NC(=O)C1CCN(C(=O)c2cnoc2C)CC1 +O=C(CS(=O)(=O)c1ccccc1Cl)N1CCCCC1 +O=C(CNC(=O)c1ccn2ccsc12)Nc1ccc2c(c1)CCC2 +COCCNC(=O)C(Sc1ccccc1)c1ccccc1 +Cc1ccc(Cl)cc1NC(=O)CCc1c(C)nn(C)c1C +CN(C)c1cc(C(=O)N2CCN(c3nccs3)CC2)ccn1 +Cc1cc(N(CC(C)C)S(=O)(=O)c2cccc(C#N)c2)no1 +COc1ccc(OC)c(N(C)c2c(-c3ccccc3)c(=O)c2=O)c1 +Cn1c(C(F)(F)F)nn(CC(=O)Nc2ccccc2)c1=O +CNC(=O)CN1CCN(C(=O)c2cc(F)c(F)cc2Cl)CC1 +O=C(NCc1ccccn1)c1ccc(OCc2cccnc2)cc1 +Cc1ccc(C(=O)Nc2ccccc2-c2nc(-c3ccco3)no2)cn1 +Fc1ccc(CNCc2nnc3n2CC(C(F)(F)F)CC3)c(F)c1 +O=C(NCc1ccc(Cl)cc1)c1cc(-c2ccccn2)[nH]n1 +Cc1cccc(NC(=O)CN(C)S(=O)(=O)c2ccccc2F)n1 +Cc1c(C#N)c2ccccc2n1CC(=O)N1CCC(CO)C(O)C1 +O=C(CCN1C(=O)c2ccccc2Sc2ncccc21)NC1CC1 +Cc1cnccc1NC(=O)NC1(C)Cc2ccccc2C1 +COC(=O)N1CCC(CNC(=O)c2ccccc2Cl)CC1 +COC(=O)NCC(=O)Nc1cccc(NC(C)=O)c1 +CC(C)C(=O)N1CCCC1C(=O)Oc1ccc2cn[nH]c2c1 +COc1ccc(NC(=O)N2CCN(C(=O)c3ccco3)CC2)cc1F +Cn1c(SCC(=O)NCC2CCCO2)nc2sccc2c1=O +Cc1noc(C)c1NC(=O)C1Cc2ccccc2O1 +CCN(CC)C(=O)c1cccc(Oc2nccc(C)n2)c1 +CC(C)c1ncc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)s1 +Cc1cc(C(=O)NCC(=O)NCC(C)CCO)c(C)o1 +Cc1cc(F)ccc1NCC(=O)Nc1cccc(C(=O)NC2CC2)c1 +COc1ccc(C#CCNC(=O)c2cc(C3CC3)on2)cc1 +CC(C)N(Cc1cccnc1)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +O=C(C1CN(C(c2ccccc2)c2ccccc2)C1)N1CCOCC1 +CCOc1ccc(C2CCCN2C(=O)c2ccccn2)cc1 +Nc1cc(Cl)ccc1C(=O)OCC(=O)Nc1ccc2c(c1)OCO2 +COC(=O)c1cccc(Oc2nc(C)cc(C)n2)c1 +CN(C)c1ncc(C(=O)Nc2nccs2)c(N)n1 +CC(C)(C)OC(=O)N1CCC(NC(=O)CCn2cncn2)CC1 +COCc1ccccc1NC(=O)N1CC(C)OC(C)C1 +CCn1c(-c2nc(-c3ccc(C#N)cn3)no2)cc2ccccc21 +Cc1cc(-c2nnc(NC(=O)Cn3cnc4ccccc43)o2)c(C)o1 +O=C(CCSc1ccccn1)NCc1cccc(C(F)(F)F)c1 +Cc1ccc(NC(=O)CCC(=O)c2cccs2)cc1 +Cc1cccc(C)c1NC(=O)CNC(=O)Nc1cccnc1 +Cc1ccc(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)nc1 +COc1ccnc(NC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1 +C#CCNCC(=O)NC(C)c1ccccc1Cl +NC(=O)c1ccc(NC(=O)CNC(=O)c2ccco2)cc1 +CC(C)CCNC(=O)c1cccnc1Oc1cccnc1 +CC1Cc2ccccc2N1C(=O)CNC(=O)NCc1ccc(F)cc1 +O=C(NCC1CCCO1)Nc1cccc(-c2nnco2)c1 +CCn1c2ccccc2c2cc(NC(=O)CCc3nc(C)no3)ccc21 +CCOC(=O)c1ccc(NC(=O)CNC(=O)C2CCCC2)cc1 +Cc1ccccc1-c1nc(C(=O)NCCO)cc2c1[nH]c1ccccc12 +O=C(Nc1cc(Cl)ccc1O)C1CC(=O)N(Cc2ccccn2)C1 +C=CCCCN(C)C(=O)NCC1(C(=O)N(C)C)CCCC1 +Cc1nc(-c2ncccn2)sc1C(=O)NCC1CCCOC1 +CCN(Cc1cccc(NC(=O)NC(C)c2ccc(C)o2)c1)C(C)=O +CCOc1cccc(NC(=O)c2cn(Cc3cccc(F)c3)nn2)n1 +CCOCC1CCCN(C(=O)CCc2cccc(OC)c2)C1 +CCN(CC)C(=O)NCc1cccnc1OCC(F)(F)F +CC(C)CC(NC(N)=O)C(=O)NCCc1cccs1 +Cc1noc(C)c1C(C)C(=O)N1CCOCC1C1CC1 +Cc1noc(C)c1CN(C)C(=O)c1c(O)cccc1O +CC1(NC(=O)CSc2cccc(Br)c2)CCOC1 +CC1Cc2ccccc2N1CCNC(=O)CNC(=O)OC(C)(C)C +COC(=O)N1CCC(c2nnc(Cn3cccn3)n2C)CC1 +CC(=O)NC1CCCN(C(=O)c2cc(C(C)C)nc3onc(C)c23)C1 +CCn1cc(NC(=O)c2ccn(C(F)F)n2)c(C(=O)OC)n1 +Nc1c[nH]nc1-c1c(Br)ccc(F)c1F +CCC(C)(CCNC(=O)c1cncnc1C)c1ccccc1OC +O=S(=O)(C1CCCCC1)N1CCc2ncncc2C1 +CC1Oc2ccc(-c3ccnc(N)n3)cc2NC1=O +CN1CCN(C(=O)CCNC(=O)c2cccs2)CC1 +COCCN(Cc1ccsc1)C(=O)c1ccccc1Cl +O=C(NCC1Cc2cc(F)cc(F)c2O1)c1cc(F)ccc1F +CCC(C)C(C(=O)NCc1ccncc1)N1Cc2ccccc2C1=O +COCCCNC(=O)N(C)C(C)c1ccncc1 +CCCNS(=O)(=O)c1ccc(C(=O)OC)cc1 +c1cnc(N2CC(Oc3cccnc3)C3OCCCC32)nc1 +CS(=O)(=O)c1cccc(S(=O)(=O)Oc2ccccc2)c1 +CCOC(=O)CC(C)CNC(=O)N1CCC(c2cnn(C)c2)CC1 +Cc1cc(NC(=O)NCCc2cccnc2)n(C2CCCCC2)n1 +COc1ccc(CCNC(=O)Cc2ccc(NC(C)=O)cc2)cc1 +CCCC(C)NC(=O)c1ccc(-c2ccco2)[nH]c1=O +Cc1noc(CNC(=O)N2CCCCCC2c2ccco2)n1 +Cc1cc(NC(=O)c2ccc(OCc3cscn3)cc2)ccn1 +CNC(=O)C(C#N)S(=O)(=O)c1ccc(C)cc1 +O=C1C(=O)N(Cc2ccccc2)c2ccc(Cl)cc21 +Cc1cc(NC(=O)C2CC2)sc1C(=O)NCC1CCOC1 +NC(=O)c1ncc(Br)c2cc(Cl)cc(Cl)c12 +Cc1cc(CN(C)CC(O)c2cccc(F)c2)no1 +CCCS(=O)(=O)N(C)C(C#N)c1cccc(C)c1 +CCc1onc(C)c1NC(=O)CSc1ccc(F)cc1 +Cc1sc(NC(=O)C2CCC2)nc1-c1ccc(F)cc1 +Cc1cc(C(=O)Nc2ccc3nn[nH]c3c2)c(F)cc1F +CC=CC1OC(=O)C2(CCCCC2)C(=O)C1(C)C +CCc1nc(N2CCN(CCO)CC2)c2cc(CC)sc2n1 +CC(C)NC(=O)C1CN(C(=O)c2ccc3c(c2)OCO3)C1 +COc1ccc(F)cc1NC(=O)NCC(C)(O)c1ccco1 +CN(CC1CCOC1)C(=O)CCOc1ccccc1F +O=C(NC1CCN(C(=O)c2ccn(C(F)F)n2)CC1)c1ccccc1 +CC(C)C1C(=O)NCCN1C(=O)Nc1ccncc1 +O=C1c2c(Br)cnn2C2CCCCN12 +COC1COC2(CCN(S(=O)(=O)N(C)C)CC2)C1 +COc1ccc(CC(C)(O)CNC(=O)C2CC2)cc1 +O=C(CN1CCN(C(=O)C2CC2)CC1)Nc1ccc2c(c1)OCO2 +COc1ccc(Nc2ncnc(Nc3ccc(C)cn3)c2N)cc1 +Cn1nc2c(c1NC(=O)c1cccc3ccccc13)CCC2 +CCn1nc(C)cc1C(=O)OC(C)c1nccs1 +C=CCNC(=O)Nc1ccc(-n2cncn2)c(C(F)(F)F)c1 +C=C(C)CN(CC)C(=O)c1ccc(OC(F)F)cc1 +CC(C)n1nnnc1-c1ccccc1NC(=O)NCC(F)F +CC(=O)Nc1ccc(NC(=O)CSc2nnc(C)n2N)cc1 +COc1ccc(-c2noc(CNC(=O)c3ccc(F)cc3)n2)cc1 +O=C(OCc1ccn(-c2ccccc2)n1)c1cc[nH]n1 +COc1cc(C)c(C(=O)N(Cc2cccc(F)c2)C2CC2)cc1OC +O=C(CN1C(=O)c2cccnc2Sc2ccccc21)NC1CC1 +CCc1nc2cc(C)cnc2n1Cc1cccc(C#N)c1 +Cc1ccc(CCC(=O)OCCN2CCCC2=O)c(C)c1 +CC(=O)Nc1ccc(Nc2cc(-n3nc(C)cc3C)ncn2)cc1 +CN(CC(=O)OC1CCCCC1)C(=O)c1cccs1 +Cc1cccc(C2CCCN2C(=O)Cn2c(=O)oc3ccccc32)c1 +CC(CN(C)C(=O)c1cc(-n2cccc2)ccc1O)N1CCOCC1 +O=C(NCc1nc(-c2ccccc2)no1)c1c[nH]nn1 +CCNC(=O)CN(CC)C(=O)CNC(=O)c1ccccc1Cl +COc1ccc(OC)c(NC(=O)C2CC(=O)N(C3CCCCC3)C2)c1 +CC(=O)Nc1ccc(C(=O)NC2CCc3ccccc32)cc1 +Cc1ccc(CNC(=O)c2c(N)n(N)c3nc4ccccc4nc23)cc1 +O=C(NCc1ccccn1)Nc1ccc(Br)cc1 +CC(C)(C#N)NS(=O)(=O)CCCc1ccccc1 +O=C(c1ccc(OCC(F)F)nc1)N1CCc2ccccc2CC1 +COC(=O)CN(c1ccc(OC)c(Cl)c1)S(C)(=O)=O +CCN(Cc1cccc(C)c1)C(=O)CNC(=O)c1cc(C)oc1C +CCN(CCC(=O)OC)C(=O)c1ccc(-n2ccnc2)nc1 +NC(=O)CN(C(=O)C1COc2ccccc2O1)C1CCCC1 +Cc1ncsc1C(=O)Nc1cc(F)ccc1SCC(F)F +CC(C)C(=O)Nc1nc2c(s1)CN(S(=O)(=O)C(C)C)CC2 +Cc1ccccc1CC(=O)Nc1ccc(NC(=O)NC2CC2)cc1 +COc1ccc(-c2nc(C(=O)NCc3ncnn3C)cs2)cc1 +CCc1nc2n(n1)CCCC2NC(=O)COc1ccccc1Cl +CC(C)Oc1cc(C(=O)NC(C)c2nc3ccccc3o2)nn1C +Cc1cc(N2CCC(C(=O)N3CCCCCC3)CC2)n2ncnc2n1 +CC1(C(=O)NCC(=O)N2CCCC2)CC1(Cl)Cl +N#Cc1ccc(N2CC3COc4ccccc4CC3(CO)C2)nc1 +O=C(COc1ccccc1-c1nnc(-c2ccccc2)o1)NC1CC1 +Cc1cc(C(=O)N2CCC3(CC2)CC(=O)Nc2ccccc23)[nH]n1 +Cc1ccccc1C(=O)Nc1sc2c(c1C(N)=O)CCCC2 +Cc1cc(C)nc(N2CCC(C(=O)NC(C)(C)C)CC2)n1 +O=C(C1CC=CCC1)N1CCc2cc(F)ccc2C1 +O=c1[nH]cccc1C1NCCc2ccc(F)c(F)c21 +O=C(CS(=O)(=O)c1ccc(F)cc1)NCC1(c2ccccc2)CC1 +Cc1nn(C)c2nc(NCCC(=O)NC3CCCCC3)sc12 +Cc1cccc(CN2CCN(C(=O)c3n[nH]c(N)n3)CC2=O)c1 +COC(=O)CC(c1c(O)n[nH]c1C)c1cccc2cccnc12 +Cc1ccc(-c2nnn(-c3ccc(F)cc3)c2N)c(C)c1 +Cc1noc(C)c1S(=O)(=O)N1CCN(S(C)(=O)=O)CC1 +CC(C)(C)C(=O)Nc1ccc(NC(=O)CCc2ccco2)cc1 +CCOc1cccc2cc(C(C)NC(=O)Cc3c(C)noc3C)oc12 +O=C(c1ccc(=O)oc1)N1CCC(Oc2ncccn2)CC1 +CCCCn1c(C)c(C)c2c1ncn1nc(-c3cccnc3)nc21 +O=C(Nc1cccc(-c2nnco2)c1)c1ccccc1-n1cnnn1 +CCc1c(C)sc2nc(-c3ccc4c(c3)OCO4)c(N)n12 +CCOC(=O)C1CCCN(C(=O)CCNC(=O)c2ccsc2)C1 +O=C(CCC(=O)N1CCN(c2ccccc2F)CC1)c1cccs1 +C=CCn1c(SC(C)c2nnc(C)o2)nnc1-c1ccncc1 +COC(=O)CSc1nnc(-c2ccc(OC(F)F)cc2)o1 +Cc1ccn2c(=NC(=O)CCc3ccc(F)c(F)c3)[nH]nc2c1 +CCc1noc(CC)c1CC(=O)NCc1ccc(OC)c(F)c1 +O=C(NCCCN1CCCCCC1=O)C1CC=CCC1 +COCCN(C)C(=O)Nc1cc(F)c(SC)c(F)c1 +O=C(c1cccs1)N1CCc2ccc(=O)[nH]c2CC1 +Cc1cccc2nc(CSc3ncc(C#N)c(N)n3)cc(=O)n12 +COC(=O)c1sc(NC(=O)CC(C)c2ccccc2)nc1C +CCc1ccc(CNC(=O)NCCCc2c(C)noc2C)s1 +Nc1c(-c2ccc(Br)cc2)nc[nH]c1=O +CCn1cc(Br)cc1C(=O)Nc1ccc(OC)cc1 +CC1CC1C(=O)NCc1ccc(N2CCCCC2=O)cc1 +CC1CCN(C(=O)c2ccc(NC(=O)N3CCCC(O)C3)cc2)CC1 +O=C(Nc1cc(-n2cccc2)ccc1F)N1CCOCC1C1CC1 +CNC(=O)C(C)N(C)C(=O)c1ccccc1-c1ncc[nH]1 +COC(=O)c1ccc(CNc2c(C)n[nH]c2C)cc1 +CCNc1ncc(C(=O)NC2CCCC2OCc2ccccc2)cn1 +COCC1c2c(cnn2CC2CC2)CCN1C(=O)c1ccoc1C +COCCCNC(=O)C(C)Nc1ccccc1C +Cc1cc(Oc2ccc(F)cc2N)nc(C(C)C)n1 +Cc1ccncc1NC(=O)NC1CCCCCC1CO +CCn1cc(-c2cc(C(F)F)c3c(C)nn(CC)c3n2)c(C)n1 +Nc1cc(C(O)CCN2CCOCC2)ccc1F +Cc1[nH]ncc1CCCNC(=O)Nn1cnc2ccccc21 +CCCNC(=O)Cn1nc2n(c(=O)c1=O)CCN2c1ccccc1 +CN(C)C(=O)Cn1cc(C(=O)N2CCc3ccccc32)nn1 +CCOC(=O)C1=C(C)NC(=O)NC1c1ccccc1C +COc1ccc(F)c(NC(=O)CNC(=O)Nc2cccc(C)c2)c1 +COc1cccc(C(=O)Nc2ccc(N)c(C)n2)c1 +C#CCNS(=O)(=O)c1cccc(C(=O)N(CC)CC)c1 +CCCCn1nnc(NC(=O)COc2cccc(C)c2)n1 +Cc1cc(-c2nnc3ccc(Br)cn23)co1 +CCc1ccc(OCc2cc(=O)n3oc(C)cc3n2)cc1 +COC(=O)c1coc(COc2cc(F)cc(F)c2C(C)=O)c1 +Cc1ccsc1CN(Cc1cccc(F)c1F)CC(C)O +Cc1csc(NC(=O)C2CCN(C(=O)Nc3ccccc3)CC2)n1 +COc1ccc(CNS(=O)(=O)c2ccc(C)c(C)c2)cc1OC +COc1cc(C(=O)Nc2nccs2)cc(Cl)c1OC(C)C +O=C1C(=O)N(Cc2cccc(F)c2)c2ccc(F)cc21 +CC(C)Oc1cccc(OCC(F)(F)F)c1C#N +O=C(c1cnc(-c2ccncc2)nc1)N1CCC1c1cccs1 +NC(=O)c1ncc(Br)c2c(Cl)cccc12 +CC(C)N(Cc1cccnc1)C(=O)NCC(C)(C)c1ccncc1 +NS(=O)(=O)c1cccnc1Nc1cccc(Cl)c1 +CCn1nc(C)cc1C(=O)Nc1ccc(C#N)cc1 +O=C(CCCN1C(=O)CSc2ncccc21)NC1CCCC1 +Cc1cccc(C(=O)NCc2cccnc2-n2cccn2)c1 +Cc1nnc(NC(=O)Cn2ncc3ccccc3c2=O)s1 +O=C(c1cccc(-n2cccn2)c1)N1CC(c2cccnc2)C1 +COc1ccc(C(=O)CSc2nncc3ccccc23)c(OC)c1 +Cc1csc2nc(-c3cccc(NC(=O)c4ccco4)c3)cn12 +CC(=O)N(C)c1ccccc1NCc1nnc(C(C)(C)C)o1 +O=C(CCSc1ccc(F)cc1)Nc1ccc(-n2cncn2)cc1 +Cn1cc(CN2CC(OCc3ccncc3)C3OCCCC32)cn1 +Cc1noc(C)c1S(=O)(=O)N(C)C(C#N)c1ccncc1 +CCc1ccc(NC(=O)CCc2cccc(N)c2)cc1 +CCC(C)c1nc2cc(Cl)ccc2n1CCCO +O=C1CCN(C(=O)c2csc3ccccc23)CC1 +CC(=O)N1CN(CCCn2ccnc2)Cc2c1sc1c2CCCC1 +CN1CC(C(=O)N2CCN(C(=O)c3ccccc3)CC2)CC1=O +CCNC(=O)c1ccc(NC(=O)C(C)Sc2ccccn2)c(C)c1 +Cc1cc(C(=O)c2cccc(Br)c2)ccn1 +CN(Cc1ccc(F)cc1)C(=O)c1ccccc1Br +N#Cc1ccc(OC(C(N)=O)c2ccccc2)c(Cl)c1 +CC(C)(C(=O)N1CCN(C(N)=O)CC1)c1ccccc1 +Cc1noc(C)c1C(=O)Oc1cccc(S(C)(=O)=O)c1 +CC(C)(C)C(=O)N1CCOc2ccc(NC(=O)c3cnns3)cc21 +CCC(=O)Oc1ccc2c3c(c(=O)oc2c1)CCC3 +CCNC(=O)C1CCCN1c1nc(C)c2cc(OC)ccc2n1 +CCOC(=O)C1CC(=O)N(c2ccc(Cl)cc2Cl)C1 +COc1ccc(Cl)cc1NC(=O)CC1C=CCC1 +O=C(CNC(=O)NCc1cccc2cccnc12)NC1CCCCC1 +OCCCn1nncc1-c1cccc(Br)c1 +CC(=O)NC(C(=O)N1CCC(C(N)=O)c2ccccc21)C1CCCC1 +C#CCN1C(=O)c2ccccc2NC1c1cccc2c1OCO2 +Cc1cc(NC(=O)c2cccc(Cl)c2Cl)no1 +O=C1CN(C(=O)Cc2ccccc2)c2ccccc2N1 +Cc1cccc(NC(=O)Cn2cnc3c(cnn3C)c2=O)n1 +COc1cc(OC)c2nc(C#N)cc(C3CC3)c2c1 +CC1CCC(N(C)C(=O)c2cccc(-n3cccn3)n2)CC1 +CC(CNS(=O)(=O)c1cccc(C#N)c1)Oc1ccccc1 +CCc1ccsc1C(=O)NCCCn1nc(C)cc1C +CC(NC(=O)CSc1ccc(F)cc1)c1ccccn1 +NC(=O)Nc1ccc(C(=O)NCc2nc3ccccc3s2)cc1 +CC1=CCC2(CO)COC(c3ccccc3O)C1C2 +Cc1ccccc1OCCCNC(=O)NC1CCCCNC1=O +CCn1cc(NC(=O)NCCN2CCCCCC2=O)cn1 +CCc1nn2c(=O)cc(CNc3ccc(F)cc3Cl)nc2s1 +CCC(CC)NC(=O)COc1ccc(N)c(C)c1 +CN(C)S(=O)(=O)c1ccc(C(=O)NCCC2=CCCCC2)o1 +COc1cccc(NC(=O)c2sc3nc(N)c(C#N)cc3c2N)c1 +Cn1cnc(CNC(=O)Nc2ccc(F)c(C(F)(F)F)c2)n1 +CC1CC(Sc2nc(NC3CC3)c3ccccc3n2)C(=O)O1 +COc1ccc(NC(=O)c2ccc3ncsc3c2)c(OC)c1 +C=CCOc1ccc(C(=O)N(CC)CC)cc1Br +O=C(Nc1ccc(OCC(=O)N2CCCCC2)cc1)c1ccco1 +Cc1ccc(-c2noc(CN3CCCC4(C3)OCCO4)n2)cc1F +O=C(Nc1nnc(-c2ccccc2)o1)c1cc2ccccc2oc1=O +O=C(NCCCOC1CCCCC1)C1CCCO1 +Cc1ccc(CC(=O)Nc2cc(F)ccc2OCC(F)(F)F)cn1 +CCC1CCCCN1C(=O)NCCc1cccc(C(=O)NC)c1 +Nc1cccc(CCCC(=O)NCc2ccccn2)c1 +COc1ncccc1NC(=O)NCCCc1cn[nH]c1C +Cc1cc(=O)n2c(n1)SCC2CC(=O)NCc1cccnc1 +COc1cc(C2CC(=O)Nc3cc4[nH]ncc4cc32)cc2c1OCO2 +CC(C(=O)NC1CC1)N1CCN(C(=O)CO)CC1 +CC1CC(C)CN(C(=O)CN2CCN(C(=O)C3CCCC3)CC2)C1 +COc1ccc(NC(=O)CCc2c(C)nn(C)c2C)c(OC)c1 +CC(C)N(CCc1nccs1)C(=O)C(N)c1ccccc1 +O=C(Nc1ccc2c(c1)OCCO2)Nc1c[nH]c2ccccc12 +CC(C)c1nnc2n1CCN(Cc1nc(-c3ccoc3)no1)C2 +O=C(Nc1ccccc1O)C1CCCN1S(=O)(=O)c1ccccc1 +CCCNC(=O)COC(=O)c1cncc(Br)c1 +O=C(CCc1ccccc1)NC1CCSc2ccccc21 +N#CC(Sc1ccccc1)n1nnc2ccccc21 +COCc1ccccc1C(=O)OCc1ccc(C)nc1 +CC(C)(C)OC(=O)C1C2C=CC1C1(C2)OCCO1 +COc1cccc(OC)c1C(=O)NCC1(O)CCOc2ccccc21 +CCOc1ncccc1C(=O)NC(C)c1ccc2c(c1)CCC(=O)N2 +CCCC(C(=O)N1CCN(S(N)(=O)=O)CC1)c1ccccc1 +O=C(CCNC(=O)c1cccs1)Oc1cccc(F)c1 +CC1(C)OCC(COC(=O)C2CC2c2cc(F)ccc2F)O1 +CCn1nc(-c2cc(F)ccc2F)cc(C(C)=O)c1=O +CCC(CCO)NC(=O)Nc1cccc(C(C)C)c1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)c1n[nH]c2c1CCC2 +CCc1cccc(C)c1NC(=O)CSc1nc2c(c(=O)[nH]1)CCC2 +Brc1cnc(N2CCCC23CCOCC3)nc1 +Cc1nc(CC(=O)Nc2cc(S(N)(=O)=O)cc(C)c2C)cs1 +c1cc2c(cc1CNc1nnc(C3CCC3)o1)OCO2 +Cn1c(-c2cccs2)nn(CCNC(=O)Cc2ccccc2)c1=O +Fc1cc2c(c(C(F)(F)F)c1)C(c1ccc[nH]1)NCC2 +COc1ccccc1NC(=O)c1ccc(NC(=O)c2ccccn2)cc1 +CCOc1ccc(C(=O)Nc2ccc(NC(C)=O)cc2)cc1C +COc1cc2c(cc1O)C(C(C)NC(C)=O)NCC2 +CCOC(=O)C1=C(C)Nc2ncnn2C1c1cccc(C)c1 +O=C(Cn1c(CO)nc2ccccc21)OC1CCCC1 +Cn1ncnc1CNS(=O)(=O)c1ccccc1Br +CC(CCC(C)(C)C)NC(=O)NCc1cccc(C#N)c1 +Cc1cc(C)c2c(CNC(=O)c3ccco3)cc(=O)oc2c1 +CN(Cc1ccco1)C(=O)Cn1cnc2ccccc2c1=O +Cc1ccc(C(=O)N2CC(S(=O)(=O)N3CCOCC3)C2)nc1 +COc1cc(CNc2ccc(NC(C)=O)cc2)cc(OC)c1 +CN(C(=O)Nc1cn[nH]c1)C1CCN(c2ccc(Cl)cc2)CC1 +CCOC(=O)c1c(C)[nH]c(C(=O)NC(C)C(C)C)c1C +CCCOc1ccc(CNC(=O)c2ccc(F)cc2)cc1OC +CCc1cnc(CNC(=O)NCC2CN3CCCCC3CO2)s1 +CNc1cc(-c2ccc(Br)cc2)nc(C)n1 +COC(=O)c1cc(C(=O)Nc2ccncc2)n(-c2ccccc2)n1 +CC(NC(=O)c1nc(C(C)C)ncc1Cl)C(=O)N(C)C +Cc1cc(NC(=O)C(C)S(=O)(=O)c2ncccc2Cl)no1 +COc1ccccc1CNC(=O)c1cc2ncsc2[nH]1 +CC(=O)c1nc2cc(Cl)ccc2n1CC(C)C +CSc1ncc(CNC2CC(=O)N(CCc3ccccc3)C2)cn1 +CCCc1cnc(C)nc1N1CC(c2ccccn2)C1 +N#Cc1ccc(CSc2nc3ncccc3[nH]2)cc1 +Nc1cc(C(=O)N2CCN(CCO)CC2)ccc1Cl +COc1cccc(-c2nc(-c3c(C)noc3C)cs2)c1 +CC(=O)NC1CC(Cc2ccccc2)OC(Cc2ccccc2)C1 +COCCCC(=O)N(C)C(C)c1cc(F)ccc1F +CCOc1ccccc1NC(=O)C(C)NC(=O)c1ccccc1F +CCc1noc(C)c1C(=O)N1CC(C)OC(C)C1 +Clc1ccc(COc2ccccc2CNc2ncn[nH]2)cc1 +CCn1nnc2cc(C(=O)NC(C)(C)c3cccc(F)c3)ccc21 +COC(=O)c1c(C)[nH]c(C(=O)NCC(C)(C)N2CCOCC2)c1C +CCc1noc(CC)c1CC(=O)NCc1oc2ccc(F)cc2c1C +CN(Cc1cnn(C)c1)C(=O)c1ccccc1Cl +Cc1ccc(C(=O)COc2ccc(C(N)=O)cc2)cc1C +O=C(NCc1cccnc1)c1nc(-c2ccc(N3CCCC3)cc2)no1 +CC(C)C(=O)Nc1nc(CCCc2c[nH]c3ccccc23)n[nH]1 +CC1CCCCN1C(=O)c1cnc(N(C)C)nc1N +CC1CC1C(NC(=O)NCc1ncn(C)n1)c1ccc(Cl)cc1 +CC(C)NC(=O)NCC1(c2ccc(F)cc2F)CC1 +CCC(C)C(NC(=O)c1cncc(Br)c1)C(N)=O +Cc1cc(NC(=O)N2CCC(CO)CC2)ccc1C(=O)N(C)C +Cc1nc(C(F)(F)F)ccc1C(=O)NCc1ccccc1 +Cc1nc(C)c(C(=O)N2CCOC(C)(c3cnn(C)c3)C2)s1 +CCOC(=O)CCN1CCCN(CC(F)(F)F)CC1 +CCn1nc(-n2cnnc2)c(NC(=O)c2ccc(F)cc2)c1C +CCN(CC)S(=O)(=O)c1ccc(N2CCCCCC2)nc1 +Cc1cnn(C2CCCN(C(=O)c3ccnc(N(C)C)c3)C2)c1 +Cc1cnc(C)c(N2CCC3(CCCN(CCO)C3=O)C2)n1 +CC1(C)Oc2ccc(N)cc2N(CCCc2ccccc2)C1=O +CCCn1c(C)cc(=O)c(O)c1CN1CCN(CCO)CC1 +Cc1cc(-c2nnc(SCC(=O)N3C(C)CCCC3C)o2)no1 +NS(=O)(=O)Cc1cc(Br)ccc1Cl +O=C(Nc1ccc(Cl)cc1)c1ccccc1NCc1ccncc1 +COc1cc(-c2noc(-c3cccc4c3OCO4)n2)ccn1 +CCC(C(=O)Nc1cccc(Cl)c1C)n1nc(C)ccc1=O +CCC(=O)Nc1cccc(C(=O)Nc2ccc(F)cc2)c1 +Cc1ccc(-n2ncc(C(=O)OCC(N)=O)c2C(F)(F)F)cc1 +Cc1cc(CN(C)C(=O)CN(C)c2ncnc3[nH]cnc23)no1 +CCN(CC)C(=O)CCC(=O)Nc1cccc(N2CCCCCC2)c1 +CC(=O)Nc1cc(C(=O)NCCCC2CCCC2)ccc1F +COC(=O)c1ccc(S(=O)(=O)NCc2cccc(C#N)c2)cc1 +CC(CCc1ncnn1CCc1ccccc1)N1CCOCC1 +CCc1noc(CCn2ccnc2-c2ccc(-c3cc[nH]n3)s2)n1 +O=C(NCC1(c2ccc(F)cc2)CC1)c1cc(=O)[nH]c2ccccc12 +CN(CC1CC1)C(=O)NCc1cn2cc(Br)ccc2n1 +CCN(CC)C(=O)c1ccccc1NC(=O)NCc1ncn(C)n1 +O=C(Nc1cccc(F)c1)C1CCN(C(=O)c2ccco2)CC1 +CC(C)(CNC(=O)c1cnc(C2CCCO2)s1)c1ccncc1 +CCCn1cc(-c2ccncc2)cc1C(=O)N(C)Cc1ccco1 +CNS(=O)(=O)c1ccc(C)c(NC(=O)Cc2ccccc2OC)c1 +O=C(Nc1ccccn1)C1CC(=O)N(c2ccc3c(c2)OCO3)C1 +Oc1ccc2oc(CCOc3ccccc3)nc2c1 +Cc1ccc(C(=O)NCc2cccc(NS(C)(=O)=O)c2)o1 +CCOC(=O)C(Cc1cccc(F)c1)=C(N)C(F)(F)F +CCOC(=O)C(C)NC(=O)c1ccc(SC)cc1 +CSc1nc(C2CC=CCC2C(=O)Nc2ccccc2)n[nH]1 +OCC1CCN(c2nc3ccccc3nc2NC2CC2)CC1 +CCOCCc1nnc(NC(=O)Cc2ccc(C)cc2)s1 +Cc1cc(C(=O)NCCc2ccc(F)cc2C)c2c(C)nn(C)c2n1 +Cc1csc(C2CCCCN2C(=O)c2cnccn2)n1 +Nc1c(NCc2ccc(Cl)cc2)ncnc1Nc1nccs1 +N#Cc1cccc(NC(=O)NCc2nc(-c3ccncc3)cs2)c1 +CS(=O)(=O)N1CCC(C(=O)OCC(=O)c2ccccc2)CC1 +O=C(Cc1nnc(-c2ccccn2)o1)NCc1ccc(F)cc1 +COC1CCCN(C(=O)C2CC2c2cccc(C(F)(F)F)c2)C1 +COC(=O)CCCNc1cc(F)cc(C(C)=O)c1 +Cc1nc(-c2nonc2N)sc1Cc1ccccc1 +N#Cc1cccnc1NCc1ccnc(-n2cccn2)c1 +CCc1noc(C)c1C(=O)NC(CC(C)C)c1ccccc1 +CSc1ccc(Cl)c(C(=O)Nc2cccnc2)c1 +Cc1cnn(CC(=O)NCC2(c3ccccc3)CC2)c1 +CCCCC1C(=O)N(C)CCN1C(=O)c1ccc(-n2cnnc2)cc1 +CS(=O)(=O)N1CCN(C(=O)Nc2cnc3ccccc3c2)CC1 +CC(C)S(=O)(=O)c1ccc(Cc2nnc(NC(=O)C3CC3)o2)cc1 +O=C(CNC(=O)c1cn2cccnc2n1)NC1CC1 +Cc1csc(NC(=O)Cc2nc(-c3cccs3)oc2C)n1 +COc1ccc(C(=O)N2CCOCC(Oc3cccnc3)C2)cc1 +Cc1ccncc1NC(=O)Cc1ccc(Cl)cc1 +O=C(NCc1nnc(C2CC2)n1C1CC1)c1cscn1 +Cc1cc(CN2CCN(C(=O)Nc3ccccc3C(C)C)CC2)on1 +CC(NC(=O)Nc1cccc(C#N)c1)c1nnnn1-c1ccccc1 +Cc1nnc(SCC(=O)NCCC2=CCCCC2)n(N)c1=O +N#Cc1cccnc1N1CCN(C(=O)c2ccccc2F)CC1 +Cc1ccc(C(=O)N2CC(C)C(O)(C3CC3)C2)s1 +CC(Oc1ccc(C#N)cc1)C(=O)OCC1CCCCO1 +Cc1ncc(CN(C)C(=O)Nc2cccc3cnccc23)s1 +Cc1cn(CC(=O)NCC(C)(C)c2ccncc2)c2ccccc12 +CCN(CC(=O)NC(C)(C)C)C(=O)Cc1ccc(F)cc1F +O=C(c1ccnc(-c2cncnc2)c1)N1CCCC1 +O=S1(=O)N=C(NCc2ccccc2Cl)Nc2ccccc21 +CCN(Cc1cccs1)C(=O)Cc1ccc2c(c1)OCCO2 +CCN(Cc1cccs1)C(=O)c1scnc1C1CC1 +CN(C)c1cccc(NC(=O)c2onc(C#N)c2N)c1 +COc1ccc(C(C)NC(=O)COC(=O)c2ccc(C)s2)cc1 +O=C(COc1ccc(F)cc1F)Nc1cccnc1N1CCCCC1 +CC(C)(C)OC(=O)N1CCCC(NC(=O)N2CCCC2)C1 +Nc1cc(NC(=O)c2ccc(Cl)cc2F)ccc1F +CCNC(=O)c1ccc(NCC(=O)Nc2c(C)nn(C)c2C)c(C)c1 +COc1ccc(CNS(=O)(=O)c2ccc(F)cc2F)cc1 +Cc1noc(C)c1C1CCCN1C(=O)c1cc(-c2ccco2)on1 +COc1ccc(NS(=O)(=O)c2ccc(-c3ccno3)o2)cc1 +Cc1c(C(=O)OCc2cccc(F)c2)nnn1-c1ccccc1 +Cn1cc(C(=O)Nc2cc(F)ccc2F)ccc1=O +CCn1c(C)nnc1CN(C)S(=O)(=O)c1cccs1 +Cc1cnc(NC(=O)CN(C)c2nc3ccccc3s2)s1 +CC(C)c1noc(CCCNC(=O)C2(c3ccc(Cl)cc3)CC2)n1 +O=C(Nc1nnc2ccccn12)C1CCCc2ccccc21 +Cc1cc(=O)[nH]c(SCC(=O)Nc2nonc2C)n1 +CC1Oc2ccc(NS(=O)(=O)c3ccccc3)cc2NC1=O +CCC(=O)NC(CC(C)(C)C)c1ccc(F)cc1 +O=C(Nc1nnc(-c2cccc(F)c2)o1)c1c[nH]c2ccccc12 +Nc1c(Cl)cc(S(=O)(=O)NCCCn2cccn2)cc1Cl +COCCC(C)NC(=O)N1CCc2c(F)ccc(F)c2C1 +C=CCN(Cc1cccs1)C(=O)NC1CCC2(CC1)OCCO2 +CC(C)COCCNC(=O)N1CCN(Cc2cccnc2)CC1 +FC(F)(F)c1cccn2c(C(F)(F)Cl)nnc12 +Cc1nc(-c2ccc(C(=O)N3CCC(C)CC3)cc2)no1 +CCCC1CN(C(=O)c2ccc3c(c2)ncn3C)CCO1 +COC(=O)C(CNC(=O)c1cc(C)n[nH]1)Oc1ccc(F)cc1 +Cc1ccc(CNC(=O)c2nc3c(o2)CN(Cc2cccnc2)C3)o1 +CCNC(=O)NCCCOC(=O)c1ccccc1C +CC(O)CN(CCO)C(=O)c1ccccc1Br +CN(C(=O)c1ccc(F)c(F)c1F)C(C#N)c1ccccc1 +COc1cccc(C(N)c2nc(CNc3ccccc3)n[nH]2)c1 +CCC1Oc2ccc(N)cc2N=C1Nc1cccc(OC)c1 +COCCN(CC(N)=O)C(=O)C1CCCN(C(=O)c2ccccc2)C1 +Cc1cccc(NC(=O)N2CCN(Cc3cnnn3C)CC2)c1 +CC(=O)N1c2ccccc2CC1C(=O)NCc1ccccn1 +Cc1ccc(C(CNC(=O)Cc2ccc[nH]2)N2CCOCC2)cc1 +CC1CCCC(OC(=O)c2cccc(S(=O)(=O)N(C)C)c2)C1 +Cc1cc(C(=O)Nc2cnn(CC(F)(F)F)c2)nc(N(C)C)n1 +Cc1n[nH]c(C2CN(C(=O)C3CC=CC3)CCO2)n1 +O=C(COC1=CC=CC2N=CC=C12)Nc1cccc(C(F)(F)F)c1 +CC1CN(C(=O)c2ccc(C#N)cc2)c2ccccc21 +CCC(C(=O)N1CCc2c(nc(C)nc2N(C)C)C1)n1cccc1 +CC(C)C(C)(C#N)NC(=O)CNc1cccc(F)c1 +CCc1nnsc1C(=O)N1CCN(C2CCCC2O)CC1 +CC(=O)c1ccc2c(c1)N(CCCCOc1ccccc1)C(=O)CO2 +Cc1cc(C)n(Cc2nn3c(C(C)C)nnc3s2)n1 +CSc1cccc(NC(=O)C(C)Oc2ccc(C(C)=O)cc2)c1 +CC(C)c1n[nH]c(NC(=O)CCCn2nnc3ccccc3c2=O)n1 +N#CCCN(CCC#N)C(=O)CNc1cccc(Cl)c1F +CC(C)(C)CCNS(=O)(=O)c1ccc(C#N)cc1 +CCN(CC)C(=O)c1cc2c(C)nn(C)c2nc1N +COC(=O)N(C)CC(=O)Nc1ccc(F)c(C(N)=O)c1 +FC(F)(F)c1nnc2ccc(NCCc3c[nH]c4ccccc34)nn12 +NC(=O)CCN(Cc1ccccc1)C(=O)Cc1ccon1 +CCCCNC(=O)c1cnc(N2CCOCC2)nc1 +Cc1cc(OC(=O)Cn2c(C)c(C)sc2=O)ccc1Cl +Cc1noc(C)c1NC(=O)NCC1COc2ccccc2O1 +CC(C)(O)CNC(=O)Nc1nc(-c2ccccc2Cl)ns1 +CC(C)Cc1ccc2c(n1)sc1c(N)ncnc12 +COCc1nc(C(=O)OC(c2ccccc2)c2ccncc2)cs1 +CC(=O)NC(C)c1nc2ccccc2n1CCc1ccccc1 +CCc1ccc(C2COCCN2C(=O)c2ccc(F)c(COC)c2)o1 +CN(C)S(=O)(=O)NCC#Cc1ccc(N2CCOC2=O)cc1 +CC(C)CC1COCCN1C(=O)Cc1cccc(F)c1 +COc1cc(-c2cn3c(nc4cc(N)ccc43)[nH]2)ccc1OC(C)C +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)CCc1ccsc1 +CCOC(=O)C1(O)CCN(C(=O)c2cc(C)oc2C)CC1 +CCn1c(C)cn2c3c(=O)n(CCC(C)C)c(=O)n(C)c3nc12 +O=C(Nc1ccccc1C(=O)NC1CC1)c1ccc2c(c1)OCCO2 +OCCn1c(C(F)(F)F)nc2ccc(F)c(F)c21 +NC(=O)CNS(=O)(=O)c1cccc(Br)c1 +CC(C(=O)Nc1ccc(Cl)cn1)N1CCN(C(=O)CO)CC1 +CC(C)C(NC(=O)COc1ccccn1)c1ccccc1 +CN(C)C(=O)CCCC(=O)NCC(C)(C)c1cccc(Cl)c1 +O=C(Nc1ccccc1OC(F)F)c1ccc2nccnc2c1 +Cc1oc(-c2ccsc2)nc1Cn1nc(-c2ccco2)oc1=O +CCC1CN(C(=O)C2COc3ccc(F)cc3C2)CC(C)O1 +O=C(Nc1ccnc2c(F)cc(F)cc12)c1ccncc1 +CCOc1ccc(C(=O)NCc2ccco2)cc1C +CC(C)C(=O)Nc1cccc(C(=O)Nc2ccc(F)c(F)c2)c1 +O=C(CNC(=O)c1cc2c(s1)SCC2)Nc1ccccc1 +COCCn1nc(-c2ccc(F)cc2)cc(CO)c1=O +O=C(Cc1c(F)cccc1F)NCC(O)c1ccccc1Cl +CC(=O)N1CCc2cc(S(=O)(=O)NC3CCC(O)CC3)ccc21 +CC(Sc1ccccc1)C(=O)NCCc1ccccn1 +CC(Oc1ccccc1)C(=O)Nc1nc2c(s1)CCCC2 +CC(NC(=O)c1cc(Br)cn1C)C(N)=O +Cc1cc(=O)[nH]c(-c2cccc(NC(=O)CCc3ccsc3)c2)n1 +CCN(CCNC(=O)c1cccnc1)c1cccc(C)c1 +CCCc1nc(NCCc2ccccc2)c(N)c(OC)n1 +Cc1ccc(OC2CCN(Cc3cnnn3C)CC2)cc1C +CCCC(=O)NC(C)c1cnn(-c2ccc(F)cc2)c1C +CC(C)N(C)S(=O)(=O)Nc1ccc(Cn2cccn2)cc1 +Cc1nccnc1N1CCC(n2cc(C(=O)NCC(C)C)nn2)CC1 +CC(C)c1ccc(S(=O)(=O)NC2(CC(N)=O)CCC2)cc1 +Cc1occc1COC(=O)c1cc(N2CCCC2=O)ccc1Cl +Cc1noc(C)c1C1CCCN1C(=O)c1ccc2c(c1)OCO2 +CN(C)S(=O)(=O)NCCNC(=O)OC(C)(C)C +COCCNS(=O)(=O)c1ccc(Cl)cc1OC +CCSc1nnc(N2CCOCC2)n1Cc1ccco1 +Cc1cccc(N2C(=O)CCC2(C)C(=O)NC2CCCC2)c1C +Cc1nc(C(=O)NCC2COc3ccccc3C2)cs1 +CCN(Cc1cnc2ccccn12)S(=O)(=O)c1c(C)noc1C +COc1ccccc1-n1nnc(-c2ccc(Cl)cc2)c1N +O=C(NCC(C1CCOC1)N1CCOCC1)C1CC1(Cl)Cl +Cc1ccc(-c2nnc(CCC(=O)N3CC(C)OCC3C)o2)cc1 +CCC(CC)(CC)NC(=O)c1cnc(C2CCCO2)s1 +Cc1nn(C)cc1C(=O)Nc1ccc(Br)c2cccnc12 +O=C(Nc1ccc(OCC(O)c2ccc(F)cc2)cc1)c1ccco1 +OC(CNCC#Cc1ccccc1)c1ccccc1 +COc1cc(C(=O)N(C)CC(O)C2CC2)ccc1C +CCCCNC(=O)Cn1ccn(-c2ccccc2C)c(=O)c1=O +CN(C)C(=O)c1ccccc1NC(=O)c1coc(-c2ccccc2)n1 +COC(=O)c1ccc(C(=O)Nc2ccnn2C2CCCCC2)cc1 +CCSc1cccc(C(=O)Nc2nnc(-c3ccno3)o2)c1 +CC(=O)c1cc(C(=O)NCCCN2CCCc3ccccc32)cs1 +Cc1nnc(SC2CCN(c3ccc(C#N)cc3)C2=O)n1N +Nc1ncnc2c1ncn2Cc1ccc(Cl)cc1 +Cn1ncc2c(N3CCC(c4ccccc4)C3)ncnc21 +CC(=O)NC1C(O)OC(COC(C)=O)C(O)C1O +O=C(CN1CCCS1(=O)=O)N1CCc2ccc(Cl)cc2C1 +CCOc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cc1 +CC(=O)NC(C(=O)NCc1cccc(Cl)c1)C(C)C +CSc1cccc(NC(=O)C(C)Sc2nc(C)cc(N)n2)c1 +NC(=O)CCNC(=O)C1COC(=O)N1Cc1cccc(O)c1 +COCCn1cc(NC(=O)Nc2ccccc2)c2ccccc21 +Cc1csc(S(=O)(=O)CC(=O)NCC(C)C)n1 +CC(C)C(=O)NC1CC(Cc2cc(CO)on2)C1(C)C +COc1ccc(NC(=O)c2cc3ccccc3oc2=O)c2cccnc12 +Oc1cccc(-c2ccc(CN3CCOCC3)cc2)c1 +CCN(CC)C(=O)c1sc(-c2ccccc2)nc1C +CC(NC(=O)OC(C)(C)C)c1nc(-c2ccc(C#N)cn2)no1 +Cc1nc(-c2cccnc2)[nH]c(=O)c1CC(=O)N(C)C(C)C(C)(C)C +COCCN1CCOCC12CCN(c1ccc(C#N)cc1)CC2 +CCCC(=O)NCc1ccc(NS(C)(=O)=O)cc1 +CCOCCNS(=O)(=O)c1cc(C)c2[nH]c(=O)cc(C)c2c1 +CC(C)C1CN(C(=O)c2ccc3c(c2)OCO3)CC1NC(=O)N(C)C +Cc1ccccc1OCCN(C)C(=O)c1cccnc1O +Cc1ccc(SCC(=O)N2CCOCC2)c(N)c1 +COc1ccc(Cl)cc1NC(=O)C(C)Oc1ccc(C(N)=O)cc1 +CCOC(=O)c1cnn(-c2ccc(OC)c(OC)c2)c1N +O=C(Nc1cccc(O)c1)c1cccc2ccccc12 +CC1CCN(C(=O)C2CCCCN2C(=O)c2ccn(C)c(=O)c2)CC1 +Cc1ccc(CN(C(C)C)S(=O)(=O)c2cnn(C)c2)o1 +O=C(NC(c1ccccc1)c1ccc2c(c1)CCCO2)c1cnn[nH]1 +CCNC(=O)CN1CCN(C(=O)Nc2ccccc2C)CC1 +COCCNC(=O)NCC1(Sc2ccccc2)CC1 +CCCNC(=O)C(C)NC(=O)c1sc2cccc(F)c2c1C +COc1ccc2c(=O)cc(C(=O)Nc3ccc(C(C)=O)cc3)oc2c1 +Cc1ccc(NC(=O)C2CC(=O)N(C3CC3)C2)c(C)c1 +Cc1nn(C)c(C)c1CC(C)NC(=O)N(C)CC1CCCCC1O +CC(C)(CNC(=O)C1COc2ccc(F)cc2C1)N1CCOCC1 +CC1(C(=O)NCCNC(=O)c2ccccc2Cl)CCCO1 +CN(C)C(=O)CSc1nnc(Cc2cccs2)n1C1CC1 +Cc1cncc(C2NCCc3c2ccc(C)c3Cl)c1 +CCc1nn(C)c(NC(=O)NCc2cnn3cccnc23)c1C +COC(=O)c1ccc(CN(C)Cc2cnc3nc(C)cc(C)n23)cc1 +Cc1cnc(C(C)(C)NC(=O)NCCCc2ccc(O)cc2)s1 +O=C(Nc1ccccn1)c1ccc(-c2noc(C(F)(F)F)n2)cc1 +CC(=O)c1sc(-c2ccncc2)nc1-c1cccs1 +COc1cc(NC(=O)CN(C)c2ccc(F)cc2)cc(OC)c1 +COCC(=O)N1CCN(C(=O)NC(C)CCC2CCCC2)CC1 +COCC1(C(=O)N(C)Cc2ccc3nonc3c2)CCC1 +Cc1ccc(C(C)NC(=O)Cn2cnc3ccccc3c2=O)o1 +Cc1ccc(C(=O)NCC(F)(F)F)cc1NCC(=O)NC1CC1 +CC(C)(C)C(=O)N1CCc2nc(NC(=O)c3ccoc3)sc2C1 +Cc1ccc(OCC(=O)Nc2cccc(C(=O)N(C)C)c2)cc1C +O=C(CC1(O)C(=O)Nc2ccc(F)cc21)c1c[nH]c2ccccc12 +COC(=O)c1cc2c(=O)n(-c3ccccc3OC)ccc2nc1C +N#Cc1cc(NC(=O)NC2(C(=O)NCC3CC3)CCCC2)ccc1F +C#Cc1cccc(NS(=O)(=O)c2cc(C)ccc2C)c1 +CCOC(=O)CS(=O)(=O)Nc1ccc(F)cc1N +CCNC(=O)N1CCN(C(C)C(=O)N2CCC(C)CC2)CC1 +CCOC(=O)C(O)(c1ccc(CC#N)cc1)C(F)(F)F +COCCCn1cc(C(=O)c2cc(F)ccc2O)cc(C#N)c1=O +CC1CN(CC(=O)N2CCCC2)c2ccc(F)cc2N1 +Cn1cc(CNC(=O)Nc2ccc(Cl)cc2)cn1 +C=C(C)c1ccccc1NC(=O)Cn1c(=O)sc2ccccc21 +Cc1noc(C)c1C(C)NC(=O)c1cccnc1OCC(F)F +CCOc1cc(F)ccc1NC(=O)c1cccc(OCC(F)F)n1 +COCCCCCC(=O)N1CC(=O)N(c2ccc(C)cc2)CC1C +CC(C)(C)c1ccc(OCC(=O)NCCO)cc1 +Cc1ccc(C(=O)N(Cc2ccsc2)CC2CCCO2)c(O)c1 +CCC(=O)NC1CCCc2ccc(C(O)CC)cc21 +CN(C(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1)c1ccccc1 +CC1CCN(c2ncc3c(n2)CC(C)(C)CC3=O)CC1 +Cc1nc2ccccc2n1CC(=O)Nc1cnn(C)c1 +CCOC(=O)CCN1CCN(C(=O)CC(F)(F)F)CC1 +COCCNC(=O)C(C)n1c(=O)c(C(F)(F)F)nc2ccccc21 +Cc1nccn1-c1ccc(NC(=O)c2ccno2)cn1 +COc1ccccc1C1OC(CO)CN1c1ccc(F)cc1 +CCCN(CCO)S(=O)(=O)c1ccc2oc(=O)ccc2c1 +COc1ccc(NC2=C(C(N)=O)S(=O)(=O)c3ccccc32)cc1 +C=CCN(CC)c1c(N)n(CCCC)c(=O)[nH]c1=O +Cc1scc(C(=O)Nc2ccc(C(=O)N3CCOCC3)cc2)c1C +O=C(NC1CC1)C1CCN(C(=O)c2cc(-c3ccncc3)[nH]n2)CC1 +Cc1ccccc1C(C)NC(=O)Cn1nnn(-c2ccccc2)c1=O +CCc1nc(CNC(=O)NCc2ccnn2C)cs1 +CCc1cccc(NC(=O)CCNC(=O)c2ccc(F)cc2F)c1 +CCOc1ccccc1N1CCN(C(=O)COc2ccccc2)CC1 +CCCCc1cn(CC2CCN(C(=O)c3cncc(C)c3)CC2)nn1 +O=c1c2ccccc2ccn1CCS(=O)(=O)NCc1ccco1 +CS(=O)(=O)c1cccc(NCc2csnn2)c1 +CN(C)C(=O)N1CCC2(CCCN(C(=O)c3cnccn3)C2)C1 +C#Cc1cccc(NCC(=O)Nc2cc(C)nn2C(C)(C)C)c1 +Cc1c(C(=O)NCC2CC2)cnn1-c1ccccc1F +Oc1cc2c(cc1OC(F)F)C(C1CC=CC1)NCC2 +CCNC(=O)c1ccc(OC)c(Br)c1 +Cc1ccccc1CCC(=O)NCc1ccc(S(N)(=O)=O)cc1 +CC(=O)c1c(C)[nH]c(C(=O)Cn2c(-c3ccccc3)noc2=O)c1C +Cc1ccc(C(=O)Nc2ccccc2C#CCO)o1 +CC(C)c1cnc(NC(=O)Cc2ccccc2)s1 +Cc1ccc(NC(=O)NCC(C)(C)C(N)=O)cc1OCC(F)F +CN1CC2(c3ccccc3)CN(C)CC(c3ccccc3)(C1)C2=O +Cc1nc2ncc3c(=O)n(-c4ccc5c(c4)OCO5)ccc3n2n1 +CCOc1nc(CC(C)C)nc(NCC2CCCO2)c1N +Fc1ccc(CN2CCOC(C3CCCO3)C2)c(F)c1 +Cc1noc(C)c1CNC(=O)CNS(=O)(=O)c1cccs1 +Nc1cccc2c1CCN(S(=O)(=O)N1CCCCC1)C2 +O=C(CCC(=O)c1ccccc1)Nc1ccnn1C1CCCCC1 +O=C(Nc1nccs1)c1cc2ccccc2c(=O)s1 +Cc1ccc(O)cc1NCc1c(C)cc(O)cc1C +O=C(NCc1ccc(Br)cc1)c1ccccc1F +COc1ccc(Cc2nc(C)nc(C(C)C)n2)cc1N +CN(Cc1csc(-c2cccs2)n1)C(=O)CN1CCOC1=O +Cc1nc(-c2ccccc2)ccc1C(=O)N1CCC(C(N)=O)C1 +Cc1ccc(C(=O)Nc2ccc(F)c(Cl)c2)cc1N +CC(C)c1nc(C2NC(=O)c3cc(Cl)ccc3N2)cs1 +O=C(NCc1ccoc1)Nc1ccc(F)cc1Br +COc1ccc2nc(NC(=O)C3CC=CC3)sc2c1 +CCN1C(=O)CCc2cc(NC(=O)c3ccsc3)ccc21 +CCOC(=O)NC1CCN(C(=O)c2ccccc2)CC1 +CCn1nc(C)c(CCNC(=O)Nc2ccc(OC)cc2)c1C +CCCCn1nc(-c2cccc(F)c2)cc(CO)c1=O +Nn1c(SCc2ccccc2F)nnc1C1CCOCC1 +O=C(c1ccc(F)cc1F)N1CCCC1c1nc2ccccc2s1 +Fc1ccc2nc(NCCN3CCOCC3)sc2c1 +COc1ccc(CNC(=O)Nc2nnc(C(C)(C)C)s2)cc1 +C=C(C)CN(CC)C(=O)c1ccc(Cn2cccn2)o1 +Cc1ccc(-c2nc(CS(=O)(=O)c3ccccn3)co2)cc1 +Cc1n[nH]c(C)c1C(=O)N(C)CC(=O)NC(C)C +COC(=O)C1CCC(=O)N1c1ccc(Cl)c(Cl)c1 +O=C(Cc1ccc(F)cc1)NCc1noc(-c2ccco2)n1 +N#CCCN(Cc1cccnc1)C(=O)Cc1ccc(O)cc1Cl +CCCCNc1nnc(-c2nnc3sccn23)s1 +CCCNC(=O)c1ccc2c(c1)CC(=O)N2Cc1ccccc1 +CCOC(=O)c1cnn(-c2ccc(C(=O)NC3CC3)cc2)c1N +COCCCNc1nccc2c(N)ccc(Cl)c12 +Cc1ccccc1CNC(=O)Cn1cc(Cl)cn1 +COc1ccc(OC)c(NS(=O)(=O)c2ccc(O)cc2)c1 +COCCN(Cc1ccccc1)C(=O)Nc1c(F)cccc1F +COc1cccc(CNC(=O)c2ccc(-c3ccco3)cc2)c1 +COc1ccccc1NC(=O)C(N)c1ccccc1 +CCN(CC)c1ccc(NC(=O)C(C)c2c(C)n[nH]c2C)cn1 +Nc1cc(Cl)ccc1C(=O)Nc1ccc2c(c1)OCO2 +COc1cc(NC(=O)N2Cc3ccccc3C2)ncn1 +Cc1cc(C(=O)NC(C)CCCC(C)C)c2c(C)nn(C)c2n1 +CCCn1nccc1NC(=O)CN1CCOC(Cn2cncn2)C1 +CC(C)OC(=O)C(C)CNC(=O)NCc1cc(=O)[nH]c2ccccc12 +COc1ncnc2c1CN(C(=O)C(C)Cc1cccc(Cl)c1)CC2 +O=C(OCCc1cccnc1)c1ccn(-c2cccc(Cl)c2)n1 +CCn1cc(NC(=O)CCOc2ccc(C)c(C)c2)ccc1=O +CCn1cc(SCC(=O)NCc2ccon2)c2ccccc21 +N#Cc1nc2cccnc2n1-c1cccc(C(F)(F)F)c1 +O=C(NCc1cc(C2CC2)[nH]n1)c1cc(-c2ccc(O)cc2)n[nH]1 +O=C(NCc1ccc(COCC(F)(F)F)cc1)Nc1ccccn1 +Cn1cc(CNC(=O)Nc2ccc(Cn3cccn3)cc2)cn1 +Cc1csc(NC(=O)CSc2nc3ncccc3o2)n1 +CCN(CC)C(=O)c1cc(C(=O)NC2CCCCCC2)n(C)n1 +CCC(=O)Nc1cccc(C(=O)NCC(C)C)c1C +Cc1cnn(CCC(=O)N2CCN(CC(O)c3ccccc3)CC2)c1 +O=C(Nc1nc[nH]n1)c1ccc(SCc2cscn2)cc1 +CCS(=O)(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +Cc1nc2ccccc2n1CCNC(=O)c1ccc2c(c1)OCO2 +CC1CCCCC1OCCSc1nncn1C +COC(CCc1ccc2c(c1)NC(=O)CCO2)(OC)OC +COC(C)(C)c1noc(-c2cnn(-c3ccccn3)c2C)n1 +COc1ccc(CC(=O)OCc2nc3ccccc3s2)cc1OC +Cc1cc(C)c(C(=O)N2CCC(CO)CC2)c(C)c1 +Nc1ccc(-c2noc(-c3ccccc3Cl)n2)cc1 +CCOC(=O)C(NCC(F)(F)F)c1cc(C)c(O)c(C)c1 +CCCN(CC(=O)N(C)C)C(=O)c1ccc(F)c(COC)c1 +CCNC(=O)C1(c2cc(-c3ccc(Cl)cc3)on2)CC1 +CC(C)NC(=O)c1ccc(Oc2ccc(Br)cc2)nc1 +CC1Cc2cc(-n3cc(Br)cn3)ccc2O1 +CCn1ccnc1SC1CCCN(Cc2ccccc2)C1=O +CCCNC(=O)CSc1nccn1Cc1ccc(F)cc1 +O=C(c1ccc2c(c1)OCO2)N(Cc1cccc2[nH]ccc12)C1CC1 +Cc1c(CNCC2(c3ccc(F)cc3F)CC2)cc(C#N)n1C +CC(C(=O)Nc1ccncc1)n1ccc(C(F)(F)F)n1 +Cc1nccc(C(=O)N2CCCC2Cn2cccn2)n1 +Cc1ccc(O)c(NS(=O)(=O)N2CCOCC2)c1 +NC(=O)CSc1ccc(-c2ccc(Br)cc2)nn1 +Cc1cc(CNC(=O)N2CCN(c3nc(C)c(C)s3)CC2)no1 +CSc1ccc(CNS(=O)(=O)c2cnn(C)c2)cc1 +Cc1ccc(NC(=O)C2CCCN(C(=O)c3cc(C)oc3C)C2)cc1 +CN1C(=O)C=C(c2ccccc2)Nc2ccccc21 +O=C(c1ccccc1NCc1ccc(F)cc1)N1CCCCC1 +O=C(c1ccc2nccnc2c1)N1CCN(c2ccccc2F)CC1 +COC(=O)Cn1ccc(=O)c2cccc(C(F)(F)F)c21 +COc1ccc(CCC(=O)N2CCCN(C(=O)C3CC3C)CC2)cc1 +Cc1noc(C)c1NC(=O)C1CC1c1cccc2ccccc12 +O=C(CC1OC(=O)c2ccccc21)c1ccc(-n2ccnc2)cc1 +COCCS(=O)(=O)N(C)Cc1ccc(C)s1 +CC(C)c1n[nH]c(C2CN(C(=O)c3cccc4cn[nH]c34)CCO2)n1 +COC(=O)C(C)(C)NC(=O)c1ccc(-c2nc(C)cs2)cc1 +CC(NC(=O)NC(C)C1CCCO1)c1ccc(F)c(F)c1 +CS(=O)(=O)NCCCNc1ccc(C#N)cc1F +COCc1cc(CNC(=O)c2ccc(-c3ccccc3Cl)o2)n[nH]1 +C=CCn1c(C)c(C)n2c3c(=O)n(C(C)C(C)=O)c(=O)n(C)c3nc12 +COc1ccc(-c2nsc(NC(=O)c3scnc3C)n2)cc1 +CCc1ccc(CNC(=O)CSc2ncn[nH]2)s1 +NC(=O)C1Cc2ccccc2CN1Cc1nnnn1-c1ccccc1 +COc1ccccc1CCC(=O)Nc1cc(-c2cccnc2)no1 +COCCOc1cc(C)ccc1NC(=O)c1cc(C(N)=O)cs1 +O=C(c1ccno1)N1CCC2(CCCN(c3ncccn3)C2)CC1 +Cn1cc(CNS(=O)(=O)c2cnn(-c3ccccc3F)c2)cn1 +CCN(CCO)C(=O)Cc1noc2c(C)c(C)c(N)cc12 +NC1=NC(=O)C(Cc2c(F)cccc2Cl)(c2ccc(F)cc2)N1 +Cc1ccccc1-n1nnc(C(=O)Nc2cccc(Cl)c2)c1N +CCC(C)C(NC(=O)C(C)Sc1ccccc1)C(N)=O +CC(C)(C)C(=O)N1CCC(C(=O)Nc2ccc3[nH]ncc3c2)CC1 +Cc1cccc(OC(C)C(=O)Nc2ccc3c(c2)OCCO3)c1 +Cc1oc(S(N)(=O)=O)cc1C(=O)NCC1CCCc2ccccc21 +COCCN(Cc1ccccc1)C(=O)c1ccc(C(N)=O)cc1 +CCCCNc1cc(C(F)(F)F)cc2c1OCC(=O)N2 +CN(Cc1ccc2c(c1)OCO2)C(=O)NCc1nnc2ccccn12 +CC1CCN(c2ncc(C(=O)N3CCCC3)c(N)n2)CC1 +CC(C)NC(=O)Nc1ccccc1N1CC(C)OC(C)C1 +CNc1ncc(C(=O)NC2CCN(c3ccc(F)cc3F)C2)s1 +Cc1ccc(OCc2ccc(C(=O)Nc3nccs3)o2)cc1 +CN1CC(C(=O)NCc2cccc(C(F)(F)F)c2)CC1=O +O=C(NC1Cc2ccccc2C1)NC1CCCC2OCCC12 +CCOC(C)C(=O)Nc1c(Cl)cc(N)cc1Cl +COCC(=O)Nc1ccc(Br)cc1C(C)C +CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2F)CC1 +Cc1nn(-c2ccc(C(=O)N3CC(C)OC(C)C3)cc2)c(C)c1Cl +Cc1cc(Cl)cc2c(=O)n(C(C)c3ncn[nH]3)cnc12 +c1cc(-c2nc(-c3ccc4c(c3)NCCO4)cs2)ccn1 +CC1(C)Cc2cccc(OCC(=O)Nc3ccc4c(c3)OCO4)c2O1 +CC1(C)CN(CCC(=O)Nc2ccc(Br)cc2)CCO1 +CC(=O)c1cccc(NC(=O)OC(C)(C)C)c1F +COC(=O)CCCN(C)S(=O)(=O)c1ccc(Cl)c(C#N)c1 +CCC(CCO)NC(=O)Nc1cccc(S(C)=O)c1 +CSc1nc(C)c(CCC(=O)N2CCCC(O)C2)c(C)n1 +CC(C)Cc1c(CO)nnn1-c1nc(-c2ccccc2)cs1 +CC(C)c1noc(COC2CCCN(C(=O)Cc3ccsc3)C2)n1 +CCNc1nc(C2COc3cc(C)c(C)cc3O2)cs1 +O=C(Nc1cccc(-n2cnnn2)c1)c1cc(F)ccc1F +O=C(NCc1ccc(-n2cnc3ccccc32)cc1)c1cnccn1 +CC(NC(=O)C1CCC1)c1cccc(N2CCCC2)c1 +Cc1c(C(=O)NC(C)C2CC2)nnn1-c1ccccc1 +Cc1ccc(C)c(C(=O)Nc2cccc(F)c2C#N)c1 +CNC(=O)c1cccc(NC(=O)C(C)NC(=O)C2CCCCC2)c1C +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1c(C)cnn1CC1CC1 +CCc1c(-c2nc(C(C)(C)OC)no2)[nH]c(C)c1C(C)=O +Cc1cc(C)c2cc(-c3cccs3)c(N)nc2n1 +Cc1cc(C)nc(-n2nc(-c3ccccc3C)cc2N)n1 +CCC(CCO)NC(=O)c1ccc2c(c1O)OC(C)(C)C2 +O=C(C1CCCC1)N1CCC(n2nnc3ccccc3c2=O)CC1 +COc1cc(NC(=O)NC(C)c2nnc3ccccn23)cc(OC)c1 +CC(=O)c1ccccc1NC(=O)c1ccc(C)c(O)c1 +Cc1cc(C)n(CCCNC(=O)N2CCOCC2C2CC2)n1 +CCNc1nnc(-c2cnn(-c3cccc(F)c3)c2C)s1 +CC(C)(CNC(=O)Nc1nc2ccccc2s1)N1CCOCC1 +CCN(CC(C)C)C(=O)c1cnn(-c2cccc(Cl)c2)c1 +Nc1cccc(NC(=O)c2ccccc2Br)c1 +Cc1ccc(C)c(NC(=O)CSc2ncccc2C#N)c1 +CN(C)C(=O)CNc1ccc(C(=O)NC(C)(C)C)cc1 +O=C(Cn1ccc(C(=O)NC2CCCCC2)n1)NC1CCCCC1 +COc1ccc(C(=O)N2CCCC2c2nc(C3CC3)no2)cc1OC +Cc1cc(C)cc(OCc2nc(CCN(C)C(=O)C(C)C)no2)c1 +CNc1snc(C)c1C(=O)OC1CCCCC1=O +CCN1CC2(CCC1=O)CCN(C(=O)c1ccc(Cl)c(C)c1)CC2 +O=C(Nc1cnc(N2CCCC2)nc1)c1ccc(Cl)cc1 +CCOC(=O)c1cn(C)nc1S(=O)(=O)N1CCOCC1 +CC(C(=O)NCCCNc1ncccn1)n1cccn1 +CCOCC(=O)NC(C)c1sc(-c2ccc(OC)cc2)nc1C +COc1c(C)cnc(CSc2nnc(C)n2CC(N)=O)c1C +COC(=O)C1CC(O)CCN1Cc1ccccc1OCCO +O=C(c1ccoc1)N1CCOC2C(OCc3cccnc3)CCC21 +CC(C)Cn1nccc1NC(=O)C1CCCN(S(C)(=O)=O)C1 +CNC(=O)Cn1cnc(NC(=O)c2ccc(-c3ccccc3)o2)n1 +CC(C)NC(=O)CNC(=O)COC(=O)c1nccnc1N +CCN(CC(=O)NC(C)C)C(=O)c1csc(Cc2ccccc2)n1 +Cc1cc(C)nc(SCCCNC(=O)Nc2ncccn2)n1 +CCOc1c(Cl)cc(-c2noc(CC#N)n2)cc1OC +C#CCN1CCN(CC(=O)NCC2(c3ccccc3)CC2)CC1 +N#Cc1cc(-c2ccc3ccccc3c2)n(CC(N)=O)n1 +Cc1noc(COC(=O)C2CC2c2ccccc2Cl)n1 +CCOC(=O)c1sc(NC(=O)c2snnc2C)c(C#N)c1C +CCNC(=O)CN(CC)C(=O)Cc1csc(C(C)C)n1 +CCNc1nc(C)cc(N2CCN(C(C)=O)CC2)n1 +Cn1c(SC2CCCCNC2=O)nc2ccsc2c1=O +N#Cc1ccc(NC(=O)COc2cccc3cccnc23)cc1 +COCCN(C)C(C(=O)NC1CC1)c1ccccc1 +Cc1ncc2c(n1)CCCC2NC(=O)C(C)(C)c1cccc(F)c1 +CCOC(CC)C(=O)NCc1cc(OC)ccc1Br +CC(C)c1ccc(OCC(=O)Nc2cn[nH]c2)cc1 +N#CCc1ccc(OCC(=O)Nc2ccccc2N)cc1 +O=S(=O)(Cc1ccc(F)cc1)NCC1COc2ccccc2O1 +CC(C)NC(=O)N1CC(c2nc(-c3ccsc3)no2)C1 +C=CCNC(=O)COc1ccc(C(=O)c2ccccc2)cc1 +Cc1nc2cc(-c3cc(F)cc(F)c3)ccc2c(=O)[nH]1 +Cc1ncc(CNC(=O)c2ccc(CC(C)C)cc2)s1 +CCNC(=O)N1CC(c2nc(Cc3ccccc3)no2)C1 +COC(=O)c1cn(C2CCCCC2)cc(C(=O)OC)c1=O +COC(=O)CNc1c(N)n(CC(C)C)c(=O)[nH]c1=O +O=C(c1nn(-c2ccccc2)c2c1COC2)N1CCc2ccccc2C1 +Cc1ccc(Br)c(NCC(=O)N2CCNC(=O)C2)c1 +Cc1csc(-c2csc(N3CCOCC3)n2)c1 +Cc1nc(CN(C)C(=O)c2ccn(C)c(=O)c2)cs1 +Cc1nc(NC(=O)c2ccc(Cc3c(C)noc3C)o2)sc1C +CN(C(=O)c1cccn(Cc2ccccc2)c1=O)c1ccccc1 +O=C1CC(C(=O)Nc2ccc(Oc3cccnc3)nc2)CN1 +CCCN1C(=O)CCc2cc(NC(=O)c3sccc3C)ccc21 +Cc1nc(-c2ccc(F)cc2)nc2c1CC(=O)N2Cc1ccco1 +NC(=O)Cn1cnc2c(nnn2-c2cccc(Cl)c2)c1=O +O=C(NCCc1ccccc1)c1cnc2ccccn2c1=O +CC(C)NC(=O)N1CCN(C(=O)c2c[nH]c(=O)[nH]2)CC1 +CCn1ncnc1CN1CCc2onc(-c3ccccc3F)c2C1 +Cc1nnc(COC(=O)c2csc3c2CCCC3)o1 +COc1cccc2c(=O)c(C(=O)N(C)c3ccccc3)c[nH]c12 +N#Cc1ccnc(SCC(=O)Nc2ccc(F)cc2Cl)c1 +CCCCN1C(=O)C(NC(C)=O)(C(F)(F)F)C(C(=O)OC)=C1C +CCOC(=O)c1sc(-c2ccc(O)cc2)nc1C +Nc1c(N2CCCc3ccccc32)ncnc1-n1nnc2ccccc21 +CS(=O)(=O)N1CCCC(C(=O)N2CCOc3ccccc32)C1 +Cc1cc(C)n(-c2ccccc2NC(=O)N(C)Cc2ccoc2C)n1 +COc1ccc(N(C)C(=O)c2cccc(N(C)C)c2)cc1OC +O=C(NCc1ccc(F)cc1)C1CSc2nccc(=O)n2C1 +CC(C(=O)N1CCC(c2ccncc2)CC1)n1cnc2ccccc21 +CC(C)Oc1ncccc1CNC(=O)NCC1CC1C +CC(Cc1ccco1)NC(=O)NCCCn1nc2n(c1=O)CCCC2 +O=C(NCC(O)CO)Nc1cc(F)ccc1N1CCCCC1 +Cc1nc(CCNC(=O)N2CCc3ccccc32)cs1 +CCN(Cc1ccccc1)C(=O)C1CN(C(=O)c2cccs2)C1 +CCNC(=O)N(C)C(c1ccccc1)c1ccccn1 +CCC(=O)N1CCN(Cc2c[nH]nc2-c2ccccc2)CC1 +Cc1nnc(NC(=O)c2nc(-c3cccs3)oc2C)s1 +O=C1CCCCN1c1ccc(S(=O)(=O)Nc2ccccc2)cc1 +CC(C)(C)Oc1ncc(S(N)(=O)=O)cc1OC1CC1 +CC(Oc1ccc(Br)cc1)C(=O)N1CCCS1(=O)=O +COc1ccc(C)cc1NC(=O)Cn1nc(C)nc1C1CCCCC1 +CC(=O)c1ccc(CN(C)C(=O)OC(C)(C)C)cc1 +CN(Cc1ccco1)C(=O)CSc1nc2ccccc2n1C +CC(COc1ccccc1)OC(=O)Cn1nc2n(c1=O)CCCCC2 +COCc1ccc(NCCCc2ccccn2)cc1 +CC(=O)c1ccc(OC(=O)C(C)OCC(F)(F)F)cc1 +COc1ccc(OCc2nnc(SCC#N)o2)cc1 +Cc1nc(C)c(CC(=O)Nc2cccc(C(C)C)c2)c(=O)[nH]1 +CCCN(Cc1ccc(S(C)=O)cc1)CC(F)F +CCOC(=O)c1cnc(-c2c(F)cccc2Cl)nc1N +CN(Cc1ccccc1)C(=O)C12CCC(C)(C(=O)C1)C2(C)C +Fc1ccc(Cl)c2c1CCNC2Cn1cnnn1 +O=C(NCCNC(=O)c1ccccc1Cl)c1cn2ccccc2n1 +Cc1ccc(Cl)cc1NC(=O)Cc1c(C)noc1C +Cc1ncc(Cl)c(C(=O)NCc2cccc(NC(C)C)c2)n1 +COC(=O)Cc1ccccc1NC(=O)c1ccncc1F +COc1ccc(NC(=O)NC(C2CC2)C2CC2)cc1F +COc1ccc(C(=O)N2CC(OCc3ccc(F)cc3Cl)C2)cc1 +CC(C)(C)Oc1cc(CNC(=O)NCC2(O)CCCCC2)ccn1 +Cc1ccc(Cl)cc1NC(=O)N1CCN(Cc2ccccn2)CC1 +COC(=O)c1sc(NC(=O)C2C3CCCC32)nc1C1CC1 +Cc1noc2ncc(C(=O)NCCc3coc(-c4ccccc4)n3)cc12 +CCCCN1CC(C(=O)Nc2nnc(C(C)C)s2)CC1=O +Cc1cccc(OCCSc2nc(-c3cccnc3)n[nH]2)c1 +Cc1cc(NC(=O)C2CC(=O)N(C3CC3)C2)ccc1Br +CC(C)Oc1ccc(C(=O)Nc2ccc(CC(N)=O)cc2)cc1 +CCOc1ccc(NC(=O)NC=Cc2ccsc2)cc1 +CCn1cc(S(=O)(=O)N(C)C(c2ccccc2)C(C)C)cn1 +Cc1ccnc(Nc2nc(CC(=O)N3CCCC(C)C3)cs2)c1 +Cc1nn(C)c2ncc(NC(=O)c3ccc(Cl)cc3F)cc12 +CCC(=O)Nc1nc2c(s1)C(=O)CC(C)(C)C2 +CC(O)C(=O)N1CCN(c2ncc(F)cn2)CC1 +CC(=O)N(C)CC(=O)NC(CC(C)C)c1cccs1 +COc1ccc(CNC(=O)c2cc(CN3CCOCC3)on2)cc1 +Cc1nc(N2CCN(C(=O)N(C)C)CC2)ccc1Br +C#CCOc1ccc(CN2CCOC(CC(=O)OC)C2)cc1 +CCOCc1cccc(CNC(=O)c2cc3ccccc3c(=O)[nH]2)c1 +CS(=O)(=O)N1CCN(C(=O)CCC2CCCO2)CC1 +Cc1ccc(F)cc1NC(=O)NCCNC(=O)C1CC1 +CC(=O)N1c2ccc(-c3cc(C#N)n[nH]3)cc2CC1C +OC(c1ccc(Cl)cc1)c1ccc(-n2ccnc2)cc1 +O=C(Nc1ccccc1F)c1ccccc1CSc1ncn[nH]1 +CCCCC(=O)NCc1ccccc1Cn1cncn1 +Cc1ccc(CS(=O)(=O)c2ccc3c(c2)OCCCO3)cc1 +CN(Cc1ccccc1)C(=O)NCc1cccnc1 +CN(C)c1ccc(Cl)cc1NC(=O)Cn1ccc(C(F)(F)F)n1 +CCOCCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CN(CCC#N)C(=O)Nc1c(F)cccc1OCc1ccccc1 +Cc1ccc(F)c(NC(=O)NCCNC(=O)c2cccnc2)c1 +O=C(Cc1ccc(F)cc1)Nc1ccc2cn[nH]c2c1 +COC(=O)C1CC(NS(=O)(=O)c2cn(C)cn2)CN1C +C=CCNC(=O)COC(=O)c1cc(Cl)cc(Cl)c1 +Cc1cc(C)cc(CCNC(=O)NCCN2CCCS2(=O)=O)c1 +CCNC(=O)CC1CSc2nc3c(c(=O)n21)CCCC3 +Cc1ccc(-c2csc(NC(=O)Cn3cccn3)n2)cc1 +CCOc1cc(CO)ccc1OCC(=O)NC(C)(C)C +Cn1nc(-c2cc(F)ccc2F)cc(CO)c1=O +CC1CCCN(S(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)C1 +CCn1cc(CNC(=O)c2c(F)cccc2F)cn1 +NS(=O)(=O)c1cc(C(=O)Nc2cccc(Cl)c2)ccc1Cl +CCOc1ccc(F)c(C(=O)N2CCN(C(=O)COC)CC2)c1F +O=C(COc1ccccc1)N1CC2CC=CCC2C1 +Cc1ccc(NC(=O)Cc2ccccc2N)cc1Cl +CC(=O)OCCCOc1ccc(Br)cc1 +Cc1nc(C(C)NC(=O)c2ccc3ncsc3c2)n[nH]1 +NC(=O)C(c1ccccc1)N1CCCN(C(=O)c2ccsc2)CC1 +COc1ccc(NC(=O)NCCNC(C)=O)cc1C +Cc1cc(NC(=O)NC2CCN(c3ccccc3)C2=O)n(C)n1 +CC1(C)Oc2ccc(NC(=O)C3CCOC3)cc2O1 +COc1ccc(C2Nc3ccc(Cl)cc3C(=O)N2C)cc1OC +Cc1ccccc1NC(=O)N1CCN(Cc2ccccn2)CC1 +Cc1cn2c(CN(C)C(=O)c3cn4cccnc4n3)c(C)nc2s1 +Cc1n[nH]c(C(NC(=O)c2ccc(Cl)cc2Cl)C(C)C)n1 +CC1CCCCN1c1ncnc(-n2cnc3ccccc32)c1N +COCC(C)OC(=O)C1CCCN(C(=O)Cc2ccccc2)C1 +COc1cccc(NS(=O)(=O)c2ccc3c(c2)OCCO3)c1 +CC(C)Cn1nccc1NC(=O)CSc1nnnn1C1CC1 +O=c1cnc2ccccc2n1Cc1cccc(Cl)c1 +CCn1c(N)c2c(=O)n(CC)c(-c3ccc(C)cc3)cc2c(C#N)c1=O +CCCn1cc(C(=O)Nc2nncs2)c2ccccc21 +CC1c2ccsc2CCN1C(=O)c1cnn(Cc2ccccc2)c1 +Cc1noc2ncc(C(=O)NC3CCCC(C)C3)cc12 +Cc1ccc(-n2cc(C(=O)N3CCCCC3)nn2)cc1 +O=C(NCCCn1cccn1)C1CCN(C(=O)c2ccoc2)CC1 +CC(=O)Nc1cccc(NC(=O)CC2C=CCC2)c1 +CCOc1ccc(C(C)O)cc1CN1CCOCC1 +COC(=O)c1ccc(Cn2nnc(C#N)c2C(C)C)cc1 +COC(=O)C1=C(C)N(C)C(=O)CC1c1ccc(OC)cc1 +O=C(c1cc2cn(C3CC3)cc2s1)N1CCCCCC1 +NC(=O)CCN(C(=O)c1cccc(Cl)c1)c1ccccc1 +Cc1ccc(CN(C(=O)CC(F)(F)F)C(C)C)s1 +Cc1cccc(N2CCN(CC(O)c3ccco3)CC2)c1C +Cc1cc(N2CCC(NS(=O)(=O)c3ccccc3)C2=O)ccc1F +Cc1cccc(OCCCCC(=O)N2CCCC(c3ccn[nH]3)C2)c1 +COCCCN(C)C(=O)c1cc2cc(Cl)ccc2[nH]1 +CCCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(C)=O +CN1CCOC(CNC(=O)Cc2cccc(F)c2)C1 +O=S(=O)(NC1CC1)c1ccc(-c2nc(-c3ccncc3)no2)cc1 +O=C(CCC(=O)c1ccc(F)c(F)c1)Oc1ccc2c(c1)OCO2 +CCCNC(=O)c1ccc(NC(=O)Cc2ccc(C)s2)cc1 +O=C(NCCc1cnc[nH]1)c1ccc(Br)cc1 +CN(CC(=O)NC1CC1)c1nc2sccn2c1CO +CCC(C)CN(C)C(=O)c1ccc(O)c(Cl)c1 +NC(=O)CCN1CCN(S(=O)(=O)c2cc(F)ccc2F)CC1 +CC(C)(C)C(O)CN1CCN(C(=O)c2n[nH]c3c2CCC3)CC1 +O=C(Cn1cccn1)Nc1ccc(N2CCCC2)nc1 +O=C(NCCCc1ccccc1)Nc1ccc(C(=O)NC2CC2)cc1 +Cn1cc(C(=O)CC2CCCN2C(=O)c2ccc(O)c(Cl)c2)cn1 +Cc1cc(C(=O)Nc2ccc(OC(F)F)cc2OC(F)F)no1 +Cc1ccc(-n2ccnc2SCC(N)=O)cc1Cl +O=C(c1ccccn1)N1CCN(C(=O)c2cc3ccoc3cn2)CC1 +CCOC(=O)C(C)NS(=O)(=O)c1ccc(C)c(C)c1 +CCNC(=O)CCc1ccc(-c2ccc(OC)cc2)o1 +COc1ccc(-c2ccc(CCC(=O)N3CCC(C(N)=O)C3)o2)cc1 +CCOc1ccccc1OCCCC(=O)N1CCN(C(C)=O)CC1 +CC(=O)Nc1ccc(Nc2nn3c(nc4cc(C#N)ccc43)[nH]2)cc1 +COc1ccc(F)cc1C(O)CCCC(=O)N1CCCC1 +CC(C)CCn1c(CO)cc(=O)c(O)c1CN1CCOCC1 +CCC(C)Oc1ccc(NS(=O)(=O)c2cccc(C(N)=O)c2)cc1 +COCC1CN(C(=O)c2cccn2C)Cc2c1cnn2C +N#Cc1cccnc1NCCOC(=O)C1CSc2ccccc2O1 +COc1cc(C(=O)NCCCC(N)=O)cc2c1OCCO2 +COc1cccc(C(=O)N(Cc2ccc(C)s2)C(C)C)c1F +Cc1c(CCNS(=O)(=O)Cc2ccc(F)c(Cl)c2)cnn1C +CCCCc1noc(C2CCN(S(=O)(=O)c3ccccc3)CC2)n1 +O=C(NCc1ccco1)c1csc(C2COc3ccccc3O2)n1 +OCCn1ncc2c1CN(c1nc3ccccc3s1)C2 +CN1CCN(C(=O)C2CCCN2C(=O)CCn2cncn2)CC1 +Cc1ccc(S(=O)(=O)Nc2ccccc2)cc1C(N)=O +Cc1cc(NC(=O)c2ccc3c(c2)OCO3)n(-c2ccccc2F)n1 +O=C(NCCOc1ccc2c(c1)OCO2)C1CCOc2ccccc21 +CN(C)S(=O)(=O)c1cccc(NCc2ccc(Cl)cc2)c1 +Nc1nc(N2CCCCC2)nn1C(=O)CC1C=CCC1 +COc1cc(F)ccc1NCc1cccc2c1OCO2 +CC(=O)c1ccc(NC(=O)C2CCCN(C(=O)C(C)(C)C)C2)cc1 +COc1ccc(Nc2ncnc3c2cnn3CCO)cc1OC +CNC(=O)c1c(NC(=O)C2CCCCC2)sc2c1CCC2 +CCC(CC)C(CNC(=O)NC(C)C)N1CCOCC1 +Cc1nn(-c2ccccc2)c2c1C(c1ccc(F)cc1)C(C#N)C(N)O2 +CCOc1ccc(C(=O)N(Cc2ccccc2)Cc2ccccc2)nn1 +CCOC(=O)N1CCN(Cc2cnoc2-c2ccccc2)CC1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc3cc[nH]c3c2)CC1 +CCOC(=O)C(CC)Sc1ccc(C(C)=O)cc1 +CCC(C(N)=O)n1c(=O)oc2cc(S(=O)(=O)N(C)C)ccc21 +Cc1cc(CN(C)C(=O)C2(C)Cc3ccccc3C(=O)O2)no1 +Cc1cccc(-c2nnc(NC(=O)c3cccs3)o2)c1 +COc1ccc(NC(=O)c2c[nH]c3ncccc23)cc1Br +Cc1cc(C)n(-c2ccc(=O)n(CCNC(=O)c3ccncc3)n2)n1 +CC(C)C(C)NC(=O)Cn1cnc2ccsc2c1=O +CC(C)NC(=O)COCc1cc(-c2cccs2)on1 +Cn1cnc(S(=O)(=O)NCc2ccccc2)c1 +O=c1onc(-c2cccs2)n1Cc1csc(-c2ncccn2)n1 +Cc1ccc(-c2ccc(CCC(=O)Nc3nnc(C)s3)o2)cc1 +COCCCCN(c1ccccc1F)S(C)(=O)=O +Cc1cc(C)c2c(C)c(C(=O)N(C)Cc3cc(C)on3)sc2n1 +O=C(c1cccc(Cl)c1)N1CCCCC1CCO +Cc1ncc(CNC(=O)COc2ccccc2Br)s1 +COc1ccc(CC(=O)Nc2ccc(N)nc2)cc1 +CC(=O)Nc1nc2ccc(NC(=O)c3ccccc3Cl)cc2s1 +Cc1cccc(NC(=O)NCC(c2cccnc2)N2CCOCC2)c1 +Cc1ccc(S(=O)(=O)n2nc(-c3ccc(Cl)cc3)nc2N)cc1 +O=C(Nc1ccc2c3c(c(=O)[nH]c2c1)CCC3)c1ccc2cc[nH]c2c1 +COc1cc2c(cc1O)C(c1cnc(C)cn1)NCC2 +Cc1cccc(S(=O)(=O)N(C)C(C#N)CC(C)C)c1 +O=C(Cc1cccs1)NCC(=O)c1ccc2c(c1)CCCC2 +COc1ccc(C)cc1C1(CNC(=O)c2ccsc2)CCOCC1 +CCN(Cc1cccc(F)c1)C(=O)CNc1cccc(NC(C)=O)c1 +COCC(O)CN(C)C(=O)c1cc(Cl)ccc1Cl +CCOC(=O)C(C)Sc1nnc2c(n1)[nH]c1ccc(C)cc12 +Cc1ccc(CNC(=O)C(C)S(=O)(=O)c2ccccc2)cc1 +COC(CNC(=O)c1ccn(-c2ccccc2F)n1)c1ccccc1 +COC(=O)Cn1ccnc1Cc1ccc(F)c(F)c1F +CCOC(=O)C(C)Nc1ccc2c(c1)CCCC(=O)N2 +COc1cccc(C(=O)c2c(N)oc3cccnc23)c1 +O=C1COC2CN(Cc3ccncc3)CC2N1Cc1ccncc1 +NC(=O)c1cccc(CNC(=O)NCCCN2CCOCC2)c1 +CCCc1cc(N2CC(n3nc(C)cc3C)C2)n2ncnc2n1 +Cc1cc(C(=O)NCC2(c3ccccc3C)CCOCC2)c(C)o1 +CN(c1c(F)cccc1F)S(=O)(=O)c1cc(F)cc(F)c1 +Cc1cc(C(=O)NCc2ccncc2)nc(N2CCCCCC2)n1 +Cc1cnc(CN2CCN(Cc3nccn3C(F)F)CC2)cn1 +OC1c2ccccc2CC1n1cnc2ccccc21 +Nc1ncccc1Cn1c(C2CC2)nc2cc(O)ccc21 +CCOC(C)C(=O)Nc1ccc(C(=O)NCC(C)C)c(Cl)c1 +COc1cccc(C(=O)Nc2ccc(-c3nnnn3C3CC3)cc2)c1 +CNC(=O)CN(C)Cc1cc(=O)oc2cc(Br)ccc12 +CCc1ccccc1NC(=O)N1CCCC1c1cc(C)on1 +O=C(COc1ccc(F)cc1)N1CCC(Nc2cccnc2)C1 +CCCCN(C)S(=O)(=O)c1ccc2c(c1)NCCO2 +CC(C)n1c(C(=O)N2CCCCC2)cc2sccc21 +NC(=O)Nc1cccc(NC(=O)c2ccc(Cn3cccn3)cc2)c1 +CN(CC(F)(F)F)C(=O)CN1CCN(c2ncccn2)CC1 +O=C(NCC(=O)N1CCc2ccccc2C1)c1ccccc1F +O=C(CCn1cncn1)Nc1cccc(N2CCOC2=O)c1 +CC(CCO)CNS(=O)(=O)c1cc2c(cc1Cl)NC(=O)CO2 +O=C(c1cc(-c2ccc(F)cc2)[nH]n1)N1CCN(CCO)CC1 +CS(=O)(=O)N1CC(C(=O)NCc2cccnc2)Oc2ccccc21 +CCc1nnc(CNC(=O)COc2ccc(Cl)cc2Cl)s1 +COc1ccc2oc(C(=O)Nc3ccccc3C(N)=O)c(C)c2c1 +O=C(COC(=O)c1cc(Cl)c[nH]1)c1ccc(N2CCCC2=O)cc1 +CC(=O)c1ccc(NC(=O)c2cccc(F)c2N)cc1 +C=CCOc1ccc(C(=O)Nc2ncc(C(N)=O)s2)cc1 +O=C(COc1ccccc1)NCc1noc(-c2cccc(Cl)c2)n1 +CCc1ccc(S(=O)(=O)N2CCOC(C)(C)C2)s1 +CN1CCCn2c1c(Br)c(=O)[nH]c2=O +O=C(NCCCn1cnc2ccccc21)c1ccc(Cl)cc1F +CNS(=O)(=O)CC(=O)NC(c1ccccc1F)C1CCCC1 +C=CCN(CC=C)C(=O)CN1CCN(c2ccc(C)cc2)C1=O +CC(=O)C1C(=O)NC2(C)CC1c1cc(Cl)ccc1O2 +CCOC(=O)c1cnn(-c2ccc(F)cc2F)c1N +N#CCC(=O)Nc1nnc(SCc2ccc(F)cc2)s1 +N#CCCN(CCC#N)C(=O)c1ccc(-c2ccc(F)cc2)o1 +O=C1COc2c(cccc2C(=O)N2CCCCCC2)N1 +COCCOc1nc(C2CCCO2)nc(NC2CC2)c1N +O=C(c1ccc2c(c1)OCCO2)N1CCOCC(CO)C1 +CC(C)OCCCNc1nc2ccccc2c(=O)n1C +Cc1ccccc1CCNC(=O)C1CCN(c2ccc(F)cc2)C1=O +COc1ccc(F)c(NC(=O)CCCc2nc(C(C)(C)C)no2)c1 +CCCCC1C(=O)N(C)CCN1C(=O)c1cnn2ccccc12 +CCCc1noc(CNc2ccc(Cl)cc2C(=O)NC)n1 +Cc1nn(C)c(C)c1C(=O)Nc1ccc2c(c1)OCCCO2 +CN1C(=O)Cc2cc(S(=O)(=O)N3CCCC3)cc(N)c21 +CCOc1ncccc1C(=O)Nc1c(C)cccc1C +O=C(CCNS(=O)(=O)c1ccccc1F)NC1CC1 +Cc1cc(SCC(=O)Nc2ccccc2)ncn1 +OC1Cc2ccccc2C1Nc1cnc2ccccc2n1 +N#Cc1cc(NC(=O)NCCNC(=O)c2cccnc2)ccc1F +CCOc1ccccc1NC(=O)c1cccn(Cc2ccccc2)c1=O +Cc1cccc(NC(=O)c2ccccc2NCc2cccnc2)c1O +COCCN(C)C(=O)NCc1sc(-c2ccccc2)nc1C +CC(C)(NC(=O)COc1ccccc1Cc1ccccc1)C(N)=O +O=C(c1cc2cccn2cn1)N1CCc2ccccc21 +O=C(c1cn(CCN2CCOCC2)nn1)N1CCc2ccccc2C1 +COc1cc(OC)c(OC)cc1CNc1ccccc1F +Cc1nnc(C2CCN(C(=O)c3ccccc3)C2)o1 +COC(=O)C1CCN(c2ncnc(NC3CCCCC3)c2N)CC1 +CC(=O)Nc1cccc(NS(=O)(=O)c2cccc(F)c2)c1 +COc1ccc(F)cc1C(=O)NCCCN1CCCC1=O +O=C1COc2ccc(Cl)cc2N1Cc1nnc(-c2ccccc2)o1 +O=c1n(Cc2nc3ccccc3s2)nnn1-c1ccccc1 +Cc1ccc(C(=O)N=c2[nH]c3ccccc3[nH]2)cc1-n1cnnn1 +COCCOc1ccc(CNc2ncc(C#N)cc2Cl)cn1 +Cc1ccc(C(=O)N2CCCC2c2ccccn2)o1 +COc1ccc(CNC(=O)COc2ccc(F)cc2F)cc1 +Nc1ccc(-c2cccc(OC(F)(F)F)c2)cn1 +COCC(=O)Nc1[nH]nc(C)c1-c1cc(OC)c(OC)c(OC)c1 +Cn1cnc2scc(-c3ccc(Cl)cc3)c2c1=O +COC(=O)c1ccc(OC(C)C(=O)Nc2ccc(F)cc2)c(OC)c1 +Cc1ccc(S(=O)(=O)N(C)C(C#N)C(C)C)cc1 +COC(=O)c1cc(NC(=O)C(C)(C)C)cc(C(=O)OC)c1 +Cn1nc(C(=O)NCCCn2ncccc2=O)ccc1=O +CS(=O)(=O)NCC(=O)Nc1cccc(Oc2ccccc2)c1 +CCN(CCC#N)C(=O)c1cnc2ccc(C)cn12 +CC(C)C(=O)Nc1nnc(SCC(=O)N(C(C)C)C(C)C)s1 +Cc1cc(NC(=O)NCC(C)CC2(C)OCCO2)c2ncccc2c1 +Cc1cc(C)c(S(=O)(=O)NCCn2cnc(C)c(C)c2=O)cc1C +Cc1ccc(S(=O)(=O)Nc2ccccc2)c2c1NCCC2 +COC(=O)c1c(C)nn(CC(=O)Nc2cccc(SC)c2)c1C +CCNc1nc(-c2ccc(C)n(CC)c2=O)cs1 +CC1c2ccccc2-c2cc(C(=O)N(C)C)ccc21 +COc1ccc(-c2csc(NC(=O)C(C)n3ccnc3)n2)cc1F +O=C(NCc1nnc2ccccn12)Nc1cc(F)ccc1Cl +O=C(CN1CCCCC1=O)Nc1ccc(Cl)c(Br)c1 +O=C(NCCC1=CCCCC1)C1CC(=O)N(Cc2ccccn2)C1 +O=C(c1cc(Cl)ccn1)N1CCCCC1CO +O=C(NCC(=O)N1CC(O)C1)c1ccccc1F +O=C(NCC(O)Cc1ccccc1)c1nc2ccccc2s1 +Cc1noc2ncc(C(=O)OCc3ccc(-n4cccn4)cc3)cc12 +COc1ccc(Oc2ncccc2NC(=O)c2cccnc2)cc1 +O=C(NC1CC(=O)N(Cc2ccccc2)C1)c1cccc2ccnn12 +O=C(NCC(=O)N1CCCC1c1ccc(O)cc1)c1ccsc1 +CC(C)C(=O)NC1CCN(Cc2ccccc2)C1=O +O=C(Cc1noc(CCc2cscn2)n1)Nc1ccccc1 +Cc1ccc(CNC(=O)c2c(C)noc2-c2ccc3c(c2)OCO3)o1 +Cc1nc2c(c(=O)n1C)CCN(C(=O)c1c[nH]c(=O)cn1)CC2 +COc1ncccc1CNC(=O)c1ccccc1F +COc1ccc(N)cc1-c1nnc2sc3c(n12)CCCC3 +CC(C)C(=O)Nc1ccc(NC(=O)CC2CCCC2)cc1 +C=CCN1C(=O)CCC2C1CCN2Cc1nccn1C +O=C(c1cc(C2CC2)[nH]n1)N1CCN(Cc2ccccc2)CC1 +COC(=O)c1ccc(S(=O)(=O)Nc2c(C)n[nH]c2C)o1 +CCn1nnnc1-c1cccc(C(=O)N(C)Cc2ccc(F)cc2)c1 +CCOC(=O)c1cnn(-c2cnnc3ccccc23)c1N +CCCc1cc(C(=O)NC2(CN3CCOCC3)CCCC2)n(C)n1 +C=CCCCN(C)S(=O)(=O)c1ccc2c(c1)N(C(C)=O)CCC2 +Cc1cc(Br)c(C)c2c1OC(C)CC(=O)N2 +O=c1ccnc(SCc2cccc(Cl)c2)[nH]1 +Cn1cnc2c1c(=O)n(CC(=O)Oc1ccc(Cl)cc1)c(=O)n2C +Cc1ccccc1NC(=O)COC(=O)c1cncc(OC(C)C)c1 +COc1ccc(S(N)(=O)=O)cc1C(=O)Nc1cccc(Cl)c1 +CCC(CC)C(=O)N1CCCC1C(=O)c1cccs1 +CC1Cc2ccccc2C1NC(=O)c1csc(S(N)(=O)=O)c1 +COc1cc(-c2ccccc2)sc1C(=O)N1CCNC(=O)C1 +CCc1nc(CC(=O)Nc2cccc(NS(N)(=O)=O)c2)cs1 +C=CCOc1ccccc1NC(=O)c1c(-c2ccncc2)noc1C +c1ccc(-c2noc(CN3CCn4c(nnc4C4CC4)C3)n2)nc1 +Cc1ccc2c(c1)CNCC2C(=O)NC1CCCCCC1 +COC(=O)CCNC(=O)c1cccc2c1ccn2C +CCCN(C)C(=O)NCc1ccc(S(=O)(=O)NC)cc1 +Cc1cc2cc(NC(=O)c3cnn(C)c3C)ccc2[nH]1 +O=C(COC(=O)Cc1ccc(F)cc1F)NC1CCCCC1 +CCc1cc(C2CCCN2C(=O)c2ccc(F)cc2)on1 +COc1ccccc1CN(C)CC(O)CN1CC(C)OC(C)C1 +CCOc1ccccc1CCNC(=O)N(C)C(C)C +NC(=O)c1ccc2[nH]c(-c3cccc(Br)c3)nc2c1 +CC(C)C(=O)N1CCN(c2ccc(N3CCOCC3)nn2)CC1 +Cc1ccc(CNS(=O)(=O)c2ccccc2N)o1 +O=C(Nc1cccc(C(F)(F)F)c1)C1(n2cnnn2)CCCCC1 +Cc1nn(C)cc1-c1cc(-c2cc3ccccc3[nH]2)c(C#N)c(N)n1 +N#CCOc1cccc(CC(=O)Nc2nc3ccc(Cl)cn3n2)c1 +COc1ccc(Cl)cc1Cn1nnc(-c2ccsc2)n1 +Cc1ccc2nc(CNC(=O)c3ccnc(-n4cnnc4)c3)[nH]c2c1C +CCC(Oc1ccccc1C)C(=O)N1CCN(CCOC)C(=O)C1 +CCCC(=O)NC1CCCOc2ccc(F)cc21 +Cc1ccncc1NC(=O)NC1CCc2c(Br)cccc21 +Cc1ccc(Nc2ncnc(-n3nc(C)cc3C)c2N)nc1 +COC(=O)c1ccc(Cl)c(NC(=O)c2ccc(NC(C)=O)cc2)c1 +O=C(CC1CCCC1)NCCNC(=O)c1c(F)cccc1F +NC(c1ccc(Br)cc1CO)C(F)(F)F +Cn1cc(CNC(=O)Nc2nc3c(s2)CCCC3)cn1 +O=S1(=O)N=C(NCC2CCC2)c2ccccc21 +CCn1nnnc1-c1cccc(C(=O)Nc2ccc(C#N)cc2)c1 +c1ccc(-c2noc(-c3cccc(-c4ccoc4)c3)n2)nc1 +Cc1nc(C(=O)Nc2ccc(C(C)C)cc2)cs1 +CC(=O)Nc1ccc2c(c1)C(=O)N1CCCC1C(=O)N2 +COc1ccc(OCC(O)CNC(=O)Nc2cc(F)ccc2C)cc1 +O=C(CN1C(=O)CSc2ccccc21)Nc1ccc(CCO)cc1 +CC(NC(=O)NCc1ccc(F)cc1)c1cccs1 +COc1cc(NCCN2CCOCC2)c(OC)cc1C +CNC(=O)Nc1ccc(NCc2cnn(C)c2)cc1 +CCn1nc(C)cc1C(=O)N1CCC2OCCCC2(COC(C)C)C1 +Nc1ccc(C(=O)CC2(O)C(=O)Nc3ccc(Cl)cc32)cc1 +COc1ccc(C(O)CNC(=O)Cn2c(C)c(C)sc2=O)cc1 +CC1CCC(NC(=O)C2CN(Cc3ccccc3)CCO2)CC1 +COc1ccc(NC(=O)CNc2ccccc2OC)cc1 +CCc1ccccc1OC1CN(c2ccc(C(=O)N(C)CC)cn2)C1 +COc1cc(COC(=O)CSc2ccncc2)ccc1C +CCOc1cccc(C(C#N)NCc2ccco2)c1 +CN(C(=O)CN1CCCC1=O)C1CCCCCC1 +CC(=O)NCCNC(=O)c1cccc2c1OCCO2 +COCC(C)NC(=O)Nc1cccc(Cl)c1Oc1cccnc1 +O=C(OCc1nc2ncc(Br)cc2[nH]1)C1CC=CCC1 +CC(C)S(=O)c1ccc(C(=O)NCc2cccc(C(N)=O)c2)cc1 +CC(C)NC(=O)NCC1(Sc2ccccc2)CCOCC1 +CC(C)Cc1cc(C(=O)NCCNC(=O)c2cccnc2)[nH]n1 +CCCn1c(=O)n(Cc2noc(-c3ccoc3)n2)c2ccccc21 +COc1ccc(NC(=O)Cc2c[nH]c3ccccc23)cn1 +Cc1ccc(CN2CCc3n[nH]c(-c4ccc5c(c4)OCO5)c3C2)o1 +CCn1c(SC(C)C(=O)N(C)CCC#N)nnc1-c1ccncc1 +Cc1ccccc1-c1nnn(CC(=O)C(C)(C)C)n1 +O=C(NCc1ccccc1F)NCC1(N2CCOCC2)CCCCC1 +N#Cc1ccc(CN2CCCN(C(=O)C3CC3c3ccco3)CC2)cc1 +CCc1nc(CC(=O)N2CCOC(c3ccc(F)cc3)C2)cs1 +Cc1[nH]ncc1S(=O)(=O)NCC1Cc2ccccc2O1 +Cc1ccnc2nc(C(=O)Nc3cc(Cl)ccc3C(N)=O)nn12 +COc1ccc(S(=O)(=O)Nc2ccc(C)c(O)c2)cc1 +CN(CCC(=O)c1ccccc1)Cc1cccs1 +CCOc1c(OC)ccc2c1CCNC2c1nc[nH]n1 +Cc1nc(C)c(C(=O)NCc2ccc(-n3ccnc3C)nc2)o1 +CCCCSc1nc2nc3c(cn2n1)C(=O)CC(C)C3 +CCn1cc(NC(=O)NCc2ccccc2OC)cn1 +Cc1nn(C)cc1C(=O)NCC(C)Oc1ccc(Cl)cc1 +CNS(=O)(=O)c1ccc(C(=O)N2CC(C)c3ccccc32)o1 +O=C(COc1ccc(-c2ccccc2)cc1)NC1CCOC1=O +COc1ccc(OC)c(CNc2nc3ccccc3n2C)c1 +CCOc1ccc(C(=O)Nc2ccc(NC(C)=O)cc2)cc1OCC +CCOC(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1 +COc1ccccc1CNC(=O)COc1ccc(Cl)cc1C(N)=O +CC(C)(C)OC(=O)N1CCC(NC(=O)Nc2ccccc2C#N)CC1 +Cn1cnc(S(=O)(=O)N2CCN3CC(OCC4CC4)CC3C2)c1 +NC(=O)c1ccc(C#CCNC(=O)Cc2c[nH]c3ccccc23)cc1 +CCS(=O)(=O)c1ccc(NC(=O)N(C)Cc2ccccc2)cc1 +NC(=O)COC(=O)c1ccc(OCC2CCCCC2)cc1 +Cc1cc(C)c(C(=O)Nc2cnn(CC3CCCO3)c2)c(C)c1 +NC(=O)c1cccc(NS(=O)(=O)c2cccc(Cl)c2)c1 +CCc1sc(C(=O)Nc2cccc(N3CCCC3=O)c2)cc1C +CC(C)NS(=O)(=O)c1ccccc1NCc1cn[nH]c1 +CCOc1ccnc(N2CCN(C(=O)COCC(F)(F)F)CC2)n1 +CNC(=O)c1ccc(OCC(F)(F)C(F)F)nc1 +CC(C)(C)c1ccccc1NC(=O)Cn1cc(N)cn1 +CCc1cc(C(=O)NCC(O)c2ccc(O)cc2)cc(=O)[nH]1 +CCOCC(=O)Nc1nc2c(s1)CN(S(=O)(=O)C(C)C)CC2 +Cn1ccnc1SCC(=O)c1cn(CCC#N)c2ccccc12 +Cc1noc(C)c1Cn1nnc(C#N)c1-c1cccc(Cl)c1 +O=c1ccccn1CCCCNS(=O)(=O)c1ccc2c(c1)CCC2 +Cc1ccccc1NC(=O)CCSc1nnnn1-c1ccccc1 +CC(CC#N)N(C)CC(=O)c1cccc(Cl)c1 +CC(OC(=O)c1cc(=O)c2ccccc2o1)C(=O)NC1CCCCC1 +Cc1ncsc1CNCc1c(F)cccc1F +Cc1nc2ccccn2c1C(=O)Nc1ccc(CC(=O)N(C)C)cc1 +Cc1cc(CN(C)Cc2ccccc2-n2cccn2)no1 +Cc1ccc(C(=O)Nc2cnn(Cc3cn4ccccc4n3)c2)cn1 +Cc1ccnc(NC(=O)CN(C)C(=O)CCNC(=O)C(C)(C)C)c1 +Cc1cc(C(=O)Nc2n[nH]c(-c3ccc(Br)cc3)n2)no1 +Nc1c(-c2ccncc2)noc1C(=O)NCc1ccco1 +Cc1nn(C)c2nc(C3CC3)cc(C(=O)NC3CCCCC3)c12 +COc1ccnc(NC(=O)C(C)c2cccs2)c1 +COc1ccc(C)c(NC(=O)c2cnn(-c3ccncc3)c2C)c1 +O=C(NC1CCCCC1)c1cnn2c(-c3cccs3)ccnc12 +COc1ccccc1NC(=O)COc1cccc(-c2nc(C)no2)c1 +CC(NC1CCc2ccccc21)C(=O)Nc1ccc(Cl)cn1 +NS(=O)(=O)c1ccc(CCNC(=O)c2n[nH]c3ccccc23)cc1 +CC(=O)Nc1cc(NC(=O)NCCCO)ccc1F +CCOc1cc(F)ccc1NC(=O)c1ccc(C(=O)N(C)C)cc1 +O=C(Cc1c(F)cccc1F)NCCNC(=O)c1ccc(F)cc1 +O=C1CC(C(=O)N(Cc2ccco2)Cc2ccco2)CN1CC1CC1 +CCNC(=O)COc1ccc(CN2CC(C)OC(CC)C2)cc1 +C#Cc1cccc(NC(=O)C2CCCN2C(C)=O)c1 +Cc1c(N)cccc1NC(=O)CCOC(C)CC(C)C +CCc1ccsc1C(=O)Nc1cccc(C(=O)NCC(N)=O)c1 +NS(=O)(=O)CCNC(=O)c1csc(-c2ccc(Cl)cc2)n1 +COc1cccc(NS(=O)(=O)c2ccc(-c3ccno3)s2)c1 +CN(CC=Cc1ccc(F)cc1)C(C(N)=O)c1cccc(F)c1 +Cc1ccc(NC(=O)N2CCCC(c3nnc4ccccn34)C2)c(C)c1 +O=C(NC1CC=CC1)N1CCOC(Cc2ccccc2)C1 +CC(C)CC(CO)Nc1ncc(C(=O)N(C)C)cc1Cl +Cc1ccc(OCC(=O)NCc2cscn2)c(C)c1 +COCCOc1cc(C)ccc1NCc1ccsc1 +O=C(Oc1ccccc1F)c1cccc2cn[nH]c12 +CC(=O)Nc1ccc(NC(C)C(=O)Nc2cc(C)no2)cc1C +CCc1oc2ccccc2c1CNc1cccnc1 +CCn1nnnc1-c1cccc(C(=O)Nc2ccc(Cl)cc2)c1 +CCN(Cc1cnc2ccccn12)C(=O)COc1cccc(C)c1 +CN(CCNC(=O)c1c[nH]c2cccc(F)c12)c1ccccc1 +CC(C)(C)OC(=O)N1CCC(c2cccc(N)c2)CC1 +CN(Cc1ccc2c(c1)OCO2)C(=O)Cc1c[nH]c2ccccc12 +COC(=O)Nc1scc(-c2ccccc2)c1C(=O)OC +COCCN1CCC2OC(C(=O)Nc3cc(C)nn3C)CC21 +COc1cccc(NC(=O)NCC2CCN(S(C)(=O)=O)CC2)c1 +Cc1ccncc1NC(=O)N1CC=C(c2cccs2)CC1 +CCCS(=O)(=O)N1CC(C)OC(c2ccccc2)C1 +COc1ccccc1NCc1ccc(NC(C)=O)cc1 +COc1ccc2[nH]c(C(C)=O)c(Br)c2c1 +COc1cccc(C(C#N)CC(=O)NCc2ccccc2)c1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc2c(c1)CCN2C(C)=O +COc1cccc(-c2ccc(OC)c3nc(N)nn23)c1 +CCCCCNC(=O)C1CCN(C(=O)c2ccccc2Cl)CC1 +CCOC(=O)CNS(=O)(=O)c1c(F)cccc1F +Cn1cccc1C1CCCCCN1S(=O)(=O)N1CCCCC1 +O=C(c1cccnc1)N1CCC2(CCN(Cc3nccs3)CC2)C1 +Cc1ccccc1CN1CCN(c2ncccn2)CC1 +O=S(=O)(c1cccnc1)N1CCN(Cc2cccc(F)c2)CC1 +CCCOc1cc(C)c(Cl)cc1S(=O)(=O)NCC1CCCO1 +CCc1nc(CCNC(=O)C2COc3ccc(F)cc3C2)sc1C +COC1CCN(C(=O)c2ccccc2Br)CC1 +Cc1nc(C(=O)N2CCC(NS(C)(=O)=O)CC2)cs1 +Cc1ccccc1C1(C(=O)N2CCCC(n3cncn3)C2)CC1 +CC1(C)CCCN1C(=O)COc1ccc2ccc(=O)oc2c1 +Cc1nn(C)c(C)c1CNC(=O)c1cnc2sccn2c1=O +CCNC(=O)CNC(=O)c1ccc2c(=O)n(CC)c(=O)[nH]c2c1 +COc1cc(CNc2ccc3c(c2)CCC3)cc(OC)c1OC +CC(C)CC1(CNC(=O)N2CCCC2CO)CCCC1 +O=C(COc1ccc(-c2nnco2)cc1)Nc1cc(Cl)ccc1F +COC(=O)c1ccc(CN2CCCC(C(=O)OC)C2)cc1F +Cc1cc(C(=O)N2CCCCC2CO)sc1C +O=C(CCN1C(=O)c2ccccc2S1(=O)=O)Nc1ccccc1F +CCOC(=O)c1sc(-n2nc(C)cc2C(F)(F)F)nc1C +Cn1c2ccccc2c2nnc(SCC(=O)N3CCOCC3)nc21 +CCn1c(CNc2ncnc3c2oc2ccccc23)nc2ccccc21 +COC(=O)CCCNC(=O)c1sccc1C1CC1 +COc1cccc(NC(=O)N2CCN(Cc3ccsc3)CC2)c1 +CC(C)c1nnc(NS(=O)(=O)Cc2ccccc2)s1 +CS(=O)(=O)N1CCCC(C(=O)NC2CCCCNC2=O)C1 +CCOc1ccc(OCC)c(S(=O)(=O)Nc2cccnc2)c1 +CC(C)C(NC1=NS(=O)(=O)c2ccccc21)C(N)=O +COCC(C)NS(=O)(=O)c1c(C)cc(C)cc1C +N#Cc1cc(-c2cccs2)n(CCN2CCOCC2)n1 +CCC(NC(=O)Nc1cc(OC)ccc1F)c1ccc(OC)cc1 +COCCCNC(=O)NCc1noc(-c2cccs2)n1 +N#Cc1ccc(Cl)cc1NC(=O)Cn1nnc(-c2ccccc2)n1 +CCc1nnc(NC(=O)C2CCCN(C(=O)NCC(C)C)C2)s1 +Cc1cc(C(=O)NCCCO)nn1-c1ccccc1 +COCCS(=O)(=O)N1CCN(c2ccc(Cl)cc2)CC1 +CC1CCN(C(=O)c2cc(F)cc(Br)c2)C(C)C1 +CC(C)Oc1ccc(C(=O)NCCC(O)c2ccco2)cc1 +Nc1cc(COc2ccc(Cl)cc2Cl)n[nH]1 +COc1ccc(C(=O)CCC(=O)Nc2ccn(C)n2)cc1OC +CC(=O)Nc1cc(C(=O)NCCCC(=O)NC2CC2)ccc1F +CC(=O)Nc1cc(NC(=O)Cc2ccc(O)cc2)ccc1F +CC1(C)OCC2(CO1)CN(C(=O)NCc1ccc(F)cc1)C2 +Cc1nc(CNC(=O)CCc2c[nH]c3c(C)cccc23)c(C)s1 +N#Cc1ccc(CNS(=O)(=O)Cc2cccc(C#N)c2)cc1 +CC(C)C(=O)N(C)Cc1cc2ccccc2[nH]c1=O +CCCCc1ccc(NC(=O)NCc2ncn(C)n2)cc1 +COCCCN(C)C(=O)c1ccc(Cl)c(N)c1 +CC(=O)N1CCC(NC(=O)c2cnn3c(C)cc(C)nc23)CC1 +CN(CC1CCCC1)C(=O)NCCS(=O)(=O)c1ccccc1 +O=C(CCSc1ccccc1)Nc1nc2c(s1)COCC2 +CN(C)c1cccc(CSc2nnnn2C2CC2)c1 +CCOc1ncccc1CNC(=O)Cc1ccc[nH]1 +CCN(CC)C(=O)CN(C)c1ncnc2c1cnn2C +O=C(NCc1ccc(N2CCCCC2=O)cc1)c1cc(Cl)c[nH]1 +COc1cccc(C(=O)N2CCN3C(=O)C(C(C)O)NC(=O)C3C2)c1 +CCCCN1C(=O)NC(NC(=O)c2cccnc2)(C(F)(F)F)C1=O +N#Cc1ccc(CS(=O)(=O)c2cccc(Cl)c2)cc1 +CCCC(=O)c1ccc2c(c1)N(CCC)C(=O)CO2 +COc1ccccc1C(C)NC(C(=O)NC1CC1)c1ccccc1 +O=C(c1ccc(OCC2CC2)nc1)N1CCCC(n2cncn2)C1 +Cc1nc(CNC(=O)Cn2cnc3c(C)cccc3c2=O)c(C)s1 +CC1CN(CCCNC(=O)N2CCOC(C)(C)C2)CC(C)O1 +CC(C)C(NC(=O)c1ccc2c(n1)NCCS2)C(=O)N1CCCC1 +COCCCN1C(=O)C(=O)c2c(Br)cccc21 +Cc1cc(C)c(C(=O)NCCC(=O)Nc2ccccc2)c(C)c1 +Cc1ccc(NC(=O)N(C)C)c(C(=O)OCc2nc(C(C)C)no2)c1 +Cc1ccc(-c2noc(CNc3cc(C(N)=O)ccc3Cl)n2)cc1 +CC(C)c1noc(CCCC(=O)Nc2cccnc2)n1 +N#CCCN(CC1CC1)C(=O)c1[nH]ncc1Br +COc1cc2nc(-c3ccccc3)[nH]c2cc1OC +CCOCCC(=O)NC(C)(C)c1ccc(Cl)cc1 +COC(=O)C(NC(=O)c1cc(C)n(C2CCCCC2)c1C)C(C)C +CCOCCOCc1cccc(NC(=O)N2CC(C)CC(C)C2)c1 +Cn1cc(C(=O)N2CCN(CCOc3ccccc3Cl)CC2)cn1 +Cc1nc(CC2CCN(C(=O)CN3CCCCCC3=O)CC2)no1 +O=C(Nc1cccc2cn[nH]c12)C1CCCCN1C(=O)c1cccnc1 +O=C(CCSc1ccccc1)NCc1cnn2ccccc12 +CC1CCC(N2CC(C(=O)NCC(=O)OCC3CC3)CC2=O)CC1 +CC(O)(CNC(=O)Nc1ccccc1CC(N)=O)c1ccsc1 +CCCNC(=O)Nc1ccc(S(=O)(=O)CC2CCCO2)cc1 +CS(=O)(=O)N1CCCCC1C(=O)Nc1ccc(Cl)cc1F +COc1cccc(OC(C)C(=O)Nc2ccc3c(c2)OCCO3)c1 +Nc1nc(C2CC2)ncc1C(=O)Nc1ccc(F)c(Cl)c1 +Cc1cc(C)c(CNC(=O)CNS(C)(=O)=O)c(=O)[nH]1 +O=C(c1ccncc1)N1CCn2nc(-c3ccccc3)nc2C1 +CC(=O)N1CCc2c(-c3ccccc3)cccc2C1C +CCC(=O)Nc1ccc(Cl)c(NC(=O)c2cc(C(C)C)[nH]n2)c1 +COc1ccc2c(c1)nc(C(C)=O)n2Cc1ccc(N)nc1 +Cc1nnc(SCC(=O)Nc2cccc(C(=O)OC(C)C)c2)n1N +CSc1ccc(CN(C)C(=O)CNC(C)=O)cc1 +Cc1cnc(C2NCCc3cc(F)c(Cl)cc32)cn1 +Cc1sc2nc(-c3cccs3)nc(NC(C)(CO)CO)c2c1C +Cc1ccc(C(NC(=O)CSc2ncn[nH]2)C2CC2)cc1 +COc1cccc(CC(=O)N2CCCN(S(C)(=O)=O)CC2)c1 +CCC(=O)N1CCc2cc(C(=O)OCc3cnn(C)c3)ccc21 +N#Cc1ccc(NC(=O)NCc2cccc(NC(=O)C3CCC3)c2)cc1 +Cc1nc(NCCNC(=O)c2ccc(F)cc2F)cc(N(C)C)n1 +Cc1cccc(CN(C)C(C(N)=O)c2cccc(F)c2)c1C +Cc1ccc(NC(=O)COC(=O)CC(C)(C)C)cc1 +CCC1c2ccccc2CCN1C(=O)NCc1ncn(C)n1 +CCC(NC(=O)CNC(C)=O)c1ccccc1OC(F)F +O=S(=O)(NCc1ccnc(OCC(F)(F)F)c1)C1CCCC1 +COc1cc2c(nn1)CCN(C(C(N)=O)c1ccc(F)cc1)C2 +COc1cc(C(=O)N2CCCC2c2cnn(C)c2)cc2c1OCCO2 +COc1cc(C(=O)Nc2c[nH]nc2C)cc(OC)c1C +Cc1ccccc1NC(=O)c1cc(Br)c[nH]1 +CCN(Cc1ccco1)C(=O)NCc1c(C)cc(C)[nH]c1=O +Cc1cccc(NCc2nnc(-c3ccccc3)o2)c1 +COc1ccc(C)cc1-c1ccc(CO)c(=O)n1C(C)C +COC1CCC(N(C)C(=O)Cc2c[nH]c3ccccc23)CC1 +Cc1cc(C(=O)NCC(=O)NCc2ccc(C)o2)n(C)n1 +N#Cc1c(N)nc2c(c1-c1c[nH]cn1)CCc1occc1-2 +Cc1cc(CC(C)NC(=O)c2cc(CN3CCOCC3)on2)[nH]n1 +CCn1c(=O)n(CCC(=O)Nc2cc(C)on2)c2ccccc21 +COc1ccc2[nH]cc(CNc3cc(C)on3)c2c1 +Cc1ccc(-n2nnnc2SCC(=O)N(C)C)cc1C +CC(C)NC(=O)c1ccccc1NC(=O)c1scnc1C1CC1 +Cc1nc2sc(-c3ccc(Br)cc3)nn2c1CO +Cc1occc1COC(=O)COC1CCCCC1C +COc1ccc(C(=O)CCCC#N)cc1C(C)(C)C +CNC(=O)NCC(=O)Nc1ccc(OC)nc1C +CC(=O)NCCNc1ccc(-n2ccc(C)n2)nn1 +CC1CN(S(=O)(=O)c2cn(C)c(=O)n(C)c2=O)CC(C)O1 +CC(=O)N1CCN(c2ncnc3c2nnn3-c2ccc(F)cc2)CC1 +CC(=O)N1CCC2(C1)CN(c1ccc(C#N)cn1)C2 +CC1(CCc2ccc(O)cc2)NC(=O)c2ccc(Cl)cc2N1 +O=C(NCCc1nccs1)NC(c1ccccc1)C1CCC1 +O=c1c(=Cc2cccc(Cl)c2)sc2nc(-c3cccnc3)nn12 +Cc1nc(C(C)NC(=O)C(c2cccc(F)c2)N2CCOCC2)no1 +O=C(NCCNS(=O)(=O)c1ccccc1)C1CC2CCC1C2 +COCCn1c(C)nc2nnc3ccc(C(=O)NC4CC4)cc3c21 +O=C(Cc1ccccc1NC(=O)c1cc2ccoc2s1)NC1CC1 +N#CCCN(C(=O)c1cc(Cl)ccc1Cl)C1CC1 +COC(=O)c1cc(-c2ccncc2)nc2ccccc12 +CC1CC(Sc2nccc(C(F)(F)F)n2)C(=O)O1 +COc1ccc(-c2cccc(-n3cnnc3)c2)cn1 +COc1ccnc(N2CCC(Oc3c(C)cccc3C)CC2)n1 +CCn1nc(C)c(Cl)c1C(=O)NCc1ccc(OC)cc1 +CCOC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1ccc[nH]1 +Cc1cc2c(SCc3nnc(C4CCC4)o3)ncnc2s1 +NC(=O)c1ccccc1NC(=O)CNc1cccc(F)c1 +O=C(Cc1ccc(F)cc1)NCCCNC(=O)c1cccc(O)c1 +COc1ccc2nc(NC(=O)c3cccc(C)n3)sc2c1 +CN(C(=O)COc1ccccc1)C(C#N)c1ccc(Cl)cc1 +Cc1cc2ncc(C(C)NCC3CC(=O)Nc4ccccc43)c(C)n2n1 +O=C(NCCc1nnc2ccccn12)C1CCOC1 +NC(=O)CNC(=O)Cc1coc2ccc3ccccc3c12 +Brc1ccn2nc(-c3cnco3)ncc12 +Cc1cc(CN2CC(C)(c3ccccc3)CCC2=O)n(C)n1 +COCCN(CCC#N)C(=O)Nc1ccc2c(c1)COC2 +Nc1ccc(C(=O)OCCCc2ccccc2)c(O)c1 +Cn1cc(C2CCCN2C(=O)c2n[nH]c(=O)c3ccccc23)cn1 +O=C(Nc1ccncc1)N1CCN(Cc2cccnc2)CC1 +COc1cccc(NC(=O)C(C)On2nnc3ccc(Cl)cc32)c1 +CCCNC(=O)C1CC(=O)N(C)C1c1ccc(C)cc1 +COc1cccc(NCc2cccc3cc[nH]c23)c1 +Cc1ccccc1C(=O)NCC(=O)NC1CN(C(=O)OC(C)(C)C)C1 +CC(C)NC(=O)CN1CCN(c2nnc(C3CCC3)o2)CC1 +O=C(CNC(=O)NC1CC1)NC1(c2ccc(Cl)cc2)CCC1 +COc1ncccc1C(=O)N=c1[nH]c2cc(Cl)ccc2n1C +CC(c1cccc(Cl)c1)N(C)C(=O)Nc1ccc(C(N)=O)cc1 +CCCN(C)S(=O)(=O)c1cc(C(=O)NC)ccc1C +CN(C)c1ncc(NC(=O)C2CCCN(CC(F)(F)F)C2)cn1 +Nc1cccc(-c2csc(=O)n2CCCO)c1 +CC(C)N1CCC(NC(=O)Nc2ncco2)C1=O +Cc1nc2cc(C(=O)N3CCOC(c4ccccc4)C3)ccc2[nH]1 +Cc1nnc2n1CCN(Cc1ccc(-n3ccnc3)cc1)C2 +O=C(Nc1ccc(-c2ccccc2)nn1)N1CCOCC1C1CC1 +CC1=NC(=O)C(CCC(=O)NCc2ccc(F)c(C)c2)C(C)=N1 +CC(=O)NC1CCOc2c1cc(C(O)C(C)(C)C)c(C)c2C +Cc1ccc2c(C)c(C(=O)Nc3ccn(CC#N)n3)oc2c1 +COc1cccc(CNc2cc(Cl)ccc2NC(C)=O)c1 +COc1ccc(OCc2ncc(C(C)(C)O)s2)cc1 +CCc1onc(C)c1NC(=O)CCc1c(C)nc(SC)[nH]c1=O +CCOC(=O)CC1CCCCN1C(=O)OCc1ccccc1 +CC(NC(=O)c1cnc2ccccn2c1=O)c1ccc(F)c(F)c1 +CC(C)(CO)NC(=O)C1(c2ccccc2)CCOCC1 +O=C(C1CC1c1ccc(F)cc1)N1CCOCC1C1CC1 +CC1Cc2ccccc2N1C(=O)c1nc2ncccn2n1 +CC(C)n1[nH]c(=O)c2c1N=C(O)CC2c1ccc(C#N)cc1 +CC(Oc1cccc(C#N)c1)C(=O)N(C)c1ccccc1 +Cc1ncsc1C(=O)NCCNC(=O)C(C)C +CNc1cc(-c2ccc(Br)cc2)ncn1 +COC(=O)CCCCc1ccc2c(c1)N(C(C)=O)CC(C)O2 +NC(=O)c1cccc(OCCCOc2ccccc2)c1 +CC(c1cc(F)ccc1F)N(C)C(=O)Nc1ccncc1F +COCCNC(=O)CC1OCC2CN(S(C)(=O)=O)CCC21 +C#CCNC(=O)N(C)Cc1cc(Cl)cc(Cl)c1 +Cc1cc(NC(=O)C2CC(=O)N(C)C2)ccc1Br +CCN1C(=O)C(C)(C(=O)NC(C)(C)C)Sc2ccccc21 +COc1ccc(O)c(C(=O)Nc2cccc(NC(C)=O)c2)c1 +O=C(COc1ccc(OCc2ccccc2)cc1)NC1CCOC1=O +COc1ccc2c(=O)cc(-c3ccc(O)c(OC)c3)oc2c1 +O=C(c1cccc2ccccc12)N1CCN(Cc2ccncc2)CC1 +O=C(Cn1nnc(-c2cccc(F)c2)n1)N1CCc2ccccc21 +Cc1cc(O)c(C(C)C)cc1NC(=O)c1ccc(S(C)(=O)=O)cc1 +COc1cccc(C(O)CNC(=O)c2ccccc2Cl)c1 +CN(C)C(=O)c1ccc(C(=O)N(C)CCN2CCOCC2)cc1 +COc1cccc(C(=O)Nc2ccc(C(=O)NC(C)C)cc2)c1O +Cc1nnc(-c2cccc(C(=O)Nc3ccc(C(F)(F)F)cc3)c2)o1 +N#CC(CC(=O)N1CCc2ccccc2C1)c1cccnc1 +CNC(=O)NCc1cn(-c2ccccc2)nc1-c1ccncc1 +Cc1nc(CN(C)C(C)C(=O)NCC2CCCO2)nc2ccccc12 +Cc1ccc2c(c1)CCCN2C(=O)Cn1cnc2ccccc2c1=O +Cc1ccc(NC(=O)NC2OC(=O)c3ccccc32)cc1 +CCOCCCNC(=O)c1cc2c(=O)[nH]c3ccc(C)cc3c2s1 +Cc1ccccc1Cn1cc(C(=O)N2CCNC(=O)C2)nn1 +COc1cc(NC(=O)c2ccc(C)c(N)c2)cc(OC)c1 +COc1ccc(COC(C)C(=O)Nc2ccccc2N)cc1 +Cc1nnc2n1CCN(CCCS(=O)(=O)c1ccc(F)cc1)C2 +CCNC(=O)CNC(=O)Nc1nn(-c2ccccc2Cl)cc1C +COc1ccc(F)cc1NC(=O)c1cnn(C)c1-n1c(C)ccc1C +Cc1noc(COC(=O)c2cnn(-c3ccc(F)cc3)c2C)n1 +COCCCOC(=O)c1ccc(Br)cn1 +COc1ccc(C(=O)Nc2cc(C)cc(C)n2)cc1OC +O=C(Nc1ccc(NCc2noc(-c3ccsc3)n2)cc1)C1CC1 +O=C(Nc1ccc(Oc2cnccn2)cc1)c1ccc(F)c(F)c1 +O=C(c1ccccc1)N1CCN(C2CC2)CC1c1ccccc1 +CC(C)(C)NC(=O)N1CCC(S(=O)(=O)c2ccccc2)CC1 +CC(C)Oc1nc(N(CCC#N)C2CC2)ccc1N +COCCNc1nnc(-c2ccc(C)n(C)c2=O)s1 +Cn1nccc1CN1CCN(C(=O)c2c(F)cccc2F)CC1 +CCCc1nn(C)c(C(=O)Nc2cc(OC)ccc2OC)c1Cl +CC(CN1CCOCC1)NC(=O)C1CCCN1S(C)(=O)=O +CCc1onc(C)c1NC(=O)c1cccc(Oc2ccncc2)c1 +c1cc(CSc2ccc(-c3ccc4c(c3)OCO4)nn2)ccn1 +Cc1nc(NCc2ccccc2-n2cccn2)c2cnn(C)c2n1 +CC1CCCN(C(=O)Nc2nc(C3CC3)cs2)C1 +CC(=O)Nc1ccc(SCC(=O)NCc2cccc(Cl)c2)cc1 +CN(C)c1cc(C(=O)Nc2cc(F)ccc2F)ccn1 +CCCCCNC(=O)c1cc2c(=O)n3cccc(C)c3nc2n1C +COC(=O)NCC(=O)N1CC2CCC1CN(C(=O)c1ccccn1)C2 +N#Cc1ccsc1NC(=O)c1cnn(-c2ccccc2)n1 +CCCOCC1CCN(C(=O)c2cc(C(C)C)nn2CC)C1 +CC1(C)CN(C(=O)NC2CCC3(CC2)OCCO3)CCO1 +Cc1noc(C)c1CN1C(=O)C2CCC1CN(c1cnccn1)C2 +Cc1ccc(C)c(NC(=O)COC(=O)c2sc(C)nc2C)c1 +Clc1cccnc1-n1ccc(NCc2nccs2)n1 +Cc1nn(CCC(=O)NCc2ccccc2F)c2ccccc12 +CCN(c1ccc(C(=O)N2CCCCCC2)cc1)S(=O)(=O)CC +Cc1ccc(Cl)c(OCC(=O)NC(C)(C)C)c1 +COC(=O)c1cc(OC)ccc1NC(=O)CC(C)C +COc1ccc(CN2CCOC3CCCCC32)cc1OC(F)F +CCN(CC(C)C#N)C(=O)COc1ccc2ccccc2c1 +O=C(NCCN1CCOCC1)c1cc(F)cc2[nH]cnc12 +Cc1cc(C)n(-c2ccc(CNC(=O)c3ccc4[nH]nnc4c3)cn2)n1 +CCc1c(C(=O)NCC(C)O)cnn1-c1ccc(F)cc1 +CCOC(=O)C1=C(C)C(C(=O)N(C)Cc2cccc(F)c2)=NC1C +C#CCNC(=O)c1ccc(OCC2CCCO2)cc1 +O=C(NCc1nnc2ccccn12)c1ccc(Br)cc1O +CC(c1cccc(O)c1)N(C)Cc1cc(O)ccc1Br +O=C(Nc1ccc2oc(=O)[nH]c2c1)c1scnc1C1CC1 +O=C(NCc1cc(F)ccc1F)N1CCCN(C(=O)C2CC2)CC1 +CC(C)(C)CCOC(=O)COc1ccc2c(c1)CCC(=O)N2 +CCCCSc1nc(N)cc(N2CCCN(C(C)=O)CC2)n1 +O=C1C(NC(=O)N(CCO)C2CC2)CCCN1Cc1ccccc1 +Cc1cc(NS(C)(=O)=O)c(=O)n(Cc2cccc(F)c2)c1 +COc1ccc(NC(=O)n2ncc3c(C)cccc32)cc1OC +CCOC(=O)c1nc2sc3c(c2c(=O)[nH]1)CCC(C)C3 +CN(C)C(=O)COC(=O)c1cccc(Oc2ccccc2)c1 +COCCn1cc(NC(=O)N2CCOCC2)c2ccccc21 +CCC(=O)Nc1nc(-c2ccccc2)nc(C)c1C(C)=O +Cc1cnc(C(=O)OCC(=O)Nc2ccccc2Cl)cn1 +CC(C)C1(CNC(=O)c2cc(N3CCCC3=O)ccc2Cl)CC1 +CC(NC(=O)Nc1nccs1)c1cccc(F)c1 +CCOc1ccccc1NC(=O)CN(C)C(=O)c1ccccc1 +O=C(NCC(c1ccc(F)cc1)N1CCOCC1)N1CCOCC1 +CCc1ccc(S(=O)(=O)CC(N)c2ccccn2)cc1 +COc1cc2c(cc1OC)C(c1cccc(OC)c1OC)CC(=O)N2 +O=C(Cc1c(F)cccc1F)NCc1nncn1C1CC1 +CCN(CC)S(=O)(=O)N1CCCC(C(F)(F)F)C1 +COc1cccc(OS(=O)(=O)c2ccc(NC(C)=O)cc2)c1 +Cc1ccc(C(=O)N2CCN(C(=O)Cc3ccccn3)CC2)cc1F +COc1cccc(C(O)CNC(=O)Cc2ccccc2)c1 +COc1cccc(C(=O)NC(C)C(=O)Nc2ccccc2)c1OC +CC(O)c1ccccc1Oc1ccc(C(N)=O)cc1 +Cc1ccc(OCC(=O)OC(C)C(=O)Nc2cc(C)on2)cc1 +O=C(Cc1cccc(F)c1)N1CCn2nc(-c3ccccc3)nc2C1 +CC(=O)NC(CC(=O)Nc1ccc(F)cc1Cl)c1ccccc1 +CN(C)c1ccc(C(=O)NCC(=O)N2CCCc3ccccc32)cc1 +NS(=O)(=O)c1ccc(CNC(=O)Nc2ccc(F)c(F)c2)cc1 +N#Cc1c(-c2cccc(OCCO)c2)cc(-c2ccc(F)cc2)nc1N +CCn1nccc1C(=O)Nc1cccc2nc(C)ccc12 +CC1(C)C2CCC(CNC(=O)c3cc(CN4CCOCC4)on3)C1C2 +O=C(NCc1ccc(OCC(F)(F)F)nc1)Nc1ccccc1F +Cc1ccnc(Nc2nc(CC(=O)N3CCNC(=O)C3)cs2)c1 +CCCCCCOC(=O)C1CCCN(C(N)=O)C1 +Cc1c(C(=O)N(CCC(N)=O)Cc2ccccc2)cnn1C(C)(C)C +Cc1ccccc1OCc1ncc(C(N)=O)c(N)n1 +CCOC(=O)Nc1ccc(NC(=O)CCn2cc(C)cn2)cc1 +COc1ccc(N)cc1-c1cc(=O)[nH]c(-c2cccs2)n1 +COc1cc(C)c(C(=O)NC2c3ccccc3CC2C)cc1OC +COc1cc(NC(=O)c2cc3ccccn3n2)cc(OC)c1 +CCOC(=O)C1=C(C)Nc2nnnn2C1c1cccc(OCC)c1 +Cc1cc(-c2nnc(CCC(=O)NCc3ccc(F)cc3)o2)n(C)n1 +CC(C)(C)n1ccnc(N2CCCC(O)C2)c1=O +Cc1cc(CNc2nnc(C(F)F)s2)ccc1-n1cncn1 +Nc1cccc(Cl)c1N1CCN(C(=O)c2cccnc2)CC1 +O=C(N=c1[nH]c2ccccc2[nH]1)c1sccc1-n1cnnn1 +COc1ccc2[nH]c(=O)c(CN(C)Cc3snnc3C)cc2c1 +N#Cc1ccc(Oc2cccc(F)c2C#N)c(N)c1 +O=C(Nc1ccc(-n2cccn2)nc1)NC1CCCCCC1 +CN(C)c1ccccc1NC(=O)NCCNC(=O)c1ccccc1O +CCOC(=O)C1=C(C)NC(=O)NC1c1cccnc1 +CCN(Cc1cc2ccccc2[nH]c1=O)C(=O)c1ccco1 +Cc1cc(C(=O)N2CCOCC2)nc2cc(-c3ccccn3)nn12 +COc1ccccc1N1CCN(c2nc(C)cs2)C(C)C1 +COCc1cccc(CNC(=O)c2n[nH]c3ccc(C)cc23)c1 +Cc1cccc(OCC(C)NC(=O)C(C)Sc2nncn2C)c1 +CCCC1CCCN(C(=O)c2cnc3ccccn3c2=O)CC1 +C=C(C)CN(CC)C(=O)C(C)Sc1nc(C)c(C)o1 +O=C(CCNC(=O)Nc1cccc(Cl)c1Cl)NC1CCCC1 +COc1cccc(C(=O)Nc2nccs2)c1O +O=C(CC1(Cn2cnnn2)CCCCC1)Nc1cccc(Cl)c1 +CCC(C)NC(=O)c1ccc(-c2cc(F)ccc2F)nc1N +Cc1csc(NC(=O)CNC(=O)c2cc(F)cc(F)c2)n1 +O=C(COc1ccc2c(c1)CCC2)N1CCC(N2CCNC2=O)CC1 +O=C(c1cc(-c2cccnc2)on1)N1CCCc2ccccc21 +Cn1cc(CNC(=O)Nc2cccc(S(N)(=O)=O)c2)cn1 +Nc1cccc(OCCCn2nnc3cc4c(cc32)OCCO4)c1 +CCn1nc(C(C)C)cc1C(=O)OCc1ccccn1 +COC(=O)c1sc2nc3c(C)cccc3cc2c1N +Cc1ccccc1-c1nnc(SCc2ccc(C(N)=O)cc2)n1C +Cc1ccc(C2CN(CC(C#N)CCC#N)CCO2)c(C)c1 +Cc1cc(Cl)ccc1-n1cc(C)c(C)c(C#N)c1=O +CCOc1ccccc1N1CCN(CC(=O)N(C(C)C)C(C)C)CC1 +Cc1cc(CN2CCN(C(=O)NC3CCCC(C)C3)CC2)on1 +O=C(Nc1nnc(CSc2ccccc2)o1)c1ccc(F)cc1 +CCC(=O)N1CCC(NC(=O)Nc2cnccc2C)C1 +Cc1nc2sccn2c(=O)c1NC(=O)COc1ccccc1 +CCOc1ccccc1-c1cc(CO)nn1C(C)C(C)=O +O=C(NCc1cn(-c2ccccc2)nc1-c1ccccc1)NC1CC1 +CCc1ncnc(NC2CCN(S(=O)(=O)CC(C)C)CC2)c1F +COc1ccc(Cc2nc3c(N)cccc3o2)cc1OC +COc1c(F)c(F)cc(C2=NC(C)(C)CO2)c1F +c1ccc(N2CCOCC3(CCCN(c4ncccn4)C3)C2)cc1 +Cc1n[nH]c(C)c1CCC(=O)N1CCc2ccccc2C1 +CCC(CC)Nc1nc(-c2ccncc2)nc2c1CCN(C(C)=O)C2 +CCn1nc(NC(=O)c2cc(C3CC3)on2)cc1C +Cc1cc(CNc2c(C)cc(Br)cc2C)no1 +Cc1ccc(C)c(OCCC(=O)Oc2ccc(-n3cnnn3)cc2)c1 +COCC(=O)N(C)CC(=O)Nc1cc(C)ns1 +CC(NC(=O)COc1ccccc1)C(O)c1ccc(F)cc1 +O=C(Cc1ccc[nH]1)N1CCc2ccccc2CC1 +CC(C)c1nnc(CS(=O)c2ccc3ccccc3c2)o1 +CCOC(C)C(=O)Nc1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +CNC(=O)C(CC(C)C)NS(=O)(=O)c1c(C)noc1C +Nc1ccc2nc(-n3nnc4ccccc43)sc2c1 +O=C(Cn1nnc2ccccc2c1=O)Nc1nccs1 +Cc1ccc(S(=O)(=O)CCC(=O)OC2CCOC2=O)cc1 +Cc1nc(-c2ccccc2)ccc1C(=O)N1CCc2sccc2C1 +COCc1cc(C(=O)NCc2cc(F)ccc2F)ccc1F +COC(=O)N1CCC(NC(=O)Cn2cc(C)c3ccccc32)CC1 +O=C(CC1C=CCC1)N1CCC(Oc2ccc(F)cc2)CC1 +COc1ccccc1C(C)CC(=O)NCc1nc(C)sc1C +CC(=O)Nc1cccc(CN2CCN(C(C#N)c3ccccc3)CC2)c1 +COc1cccc(N2CCC(CNC(=O)NCc3ncn(C)n3)C2)c1 +COc1ccc(OC)c(NC(=O)Nc2ccc(C)cn2)c1 +Cc1nnc(C2CCCN2C(=O)c2csc(-c3ccsc3)n2)o1 +Cn1c(=O)ccn(CC(=O)Oc2cccc(F)c2)c1=O +C#CCNC(=O)N1CCN(Cc2csc(C(C)(C)C)n2)CC1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)C(C)c1ccsc1 +O=C(Nc1ccccc1)c1ccc(S(=O)(=O)c2ccccc2)o1 +CC(=O)N1CCC(C(=O)Nc2cccc(-c3cn[nH]c3)c2)CC1 +COCC(NC(=O)C1C(C=C(C)C)C1(C)C)C(N)=O +O=C(Cn1cncn1)NCCCNc1ncccn1 +COc1ccc(C(=O)N2c3ccccc3CC2C)cc1N +O=C(Nc1ccccc1)C1CCCN(C(=O)c2ccco2)C1 +COc1cccc(N(CC(=O)NCc2cccnc2)S(C)(=O)=O)c1 +CC(=O)C(C)n1nc(CO)cc1-c1ccc2c(c1)CCC2 +Cc1ccc(Nc2ncnc(Oc3cccnc3)c2N)c(C)c1 +Cc1nc(CC(=O)N2CCC(OCc3ccc(F)cc3)CC2)cs1 +CC1CC(=O)Nc2c1c(NC(=O)c1cc(-c3ccco3)n[nH]1)nn2C +CCC(NC(=O)Cc1c[nH]c2ccccc12)c1nccs1 +CC(=O)Nc1cc(C)c(S(=O)(=O)Nc2cccc(F)c2)c(C)c1 +NC(=O)c1ccc(C(=O)NCc2ccc3c(c2)OCO3)nc1 +CCOc1ccc(OCC(=O)Nc2ccc(Cl)c(N)c2)cc1 +COc1ccc2nc(SCC3CCCCO3)[nH]c2c1 +O=C(Nc1cccc(OCc2cccnc2)c1)c1cnns1 +CC1CCN(C(=O)c2cccc(OC(F)F)c2)C(C)C1 +CC(C)(C)C(=O)Nc1c(C(=O)N2CCCC2)oc2ccccc12 +Cc1cc(C)cc(OCCCSc2nnc(C)c(=O)n2N)c1 +COc1cccc(C(C#N)CC(=O)N2CCOCC2)c1 +CC(C)COCCC(=O)NC1CCN(C(=O)c2ccccc2O)CC1 +CS(=O)(=O)Nc1ccc(C(=O)Nc2ccccc2O)cc1 +COc1ccc(C)cc1C(O)CNC(=O)CC(C)C +CN(C)c1c2c(nn3c(C4COCCN4)nnc13)CCC2 +Cc1csc2nc(CN3CCOCC3)[nH]c(=O)c12 +Cc1cc(S(=O)(=O)N2CCC(C(N)=O)CC2)ccc1OC(C)C +CCC(C)n1nccc1NC(=O)c1ccc(OCC(F)F)nc1 +CC1CCC(NC(=O)Cn2nnc(-c3ccc(C(N)=O)cc3)n2)CC1 +CCCCNC(=O)Nc1ccc(C#CCO)cc1F +Oc1ccc2c(c1)CCNC2C=Cc1ccncc1 +CC(C)c1noc(C(C)Sc2nnc3ccccn23)n1 +N#Cc1c(-c2ccc3c(c2)NC(=O)CO3)coc1N +N#Cc1cccc(NC(=O)Nc2ccn(CC(N)=O)n2)c1 +CCNC(=O)C(C)NC(=O)NC1CCc2ccccc21 +COC(=O)c1cnc(NC(=O)c2ccccc2-n2cnnn2)s1 +Cc1ccccc1C(C)NC(=O)NCc1cnn(C)c1 +CCOc1ccccc1NC(C)C(=O)Nc1cccc(NC(C)=O)c1 +Cc1ccc(CNC(=O)Cc2ccc(N3CCCC3=O)cc2)cc1 +CC(C)C(=O)NCCn1nc(C2CC2)n(-c2ccccc2)c1=O +Cc1cccc(N(CCC(N)=O)Cc2csc(C)n2)c1 +CCN(CC)C(=O)CCC(=O)N1CCCC1c1ccc(OC)cc1 +CCC(C(N)=O)N(c1ccc(Cl)cc1)S(C)(=O)=O +O=C(NCCNC(=O)c1ccccc1O)Nc1cc(F)cc(F)c1 +NC(=O)CCC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +COc1cccc(N2CCN(C(=O)NCC(F)(F)F)CC2)c1 +COc1ccc(C(C)NC(=O)c2nccnc2N)cc1F +COc1cc(=O)n(-c2ccc(C)cc2)nc1C(=O)NC(C)(C)C +Cc1nc(C2CCN(c3nc(N)nc4c3CCCC4)CC2)no1 +Cc1cccc(CNC(=O)NCC(O)COc2ccc(F)cc2)n1 +CS(=O)(=O)Nc1cccc(NC(=O)c2ccccc2)c1 +CCOc1cc(C(=O)N2CCOCC2C)cc(OCC)c1OCC +CC(C)(C)OC(=O)NCC#Cc1ccc(N2CCNC2=O)cc1 +Cc1cnc(CCN(C)C(=O)c2cnn(-c3ccncc3)c2C)s1 +Cc1nn(CCO)c2c(Br)c(O)ccc12 +Cc1cc(CN(C)C(=O)c2ccc(C(=O)NC(C)(C)C)cc2)no1 +CCC(=O)Nc1cccc(C(=O)Nc2cccnc2C)c1 +Cc1noc(C2CCN(C(=O)CCc3cccs3)CC2)n1 +Cc1ccc(CN2CCc3ccc(=O)n(CC4CC4)c3CC2)o1 +CCn1cc(S(=O)(=O)N2CCN(Cc3ccccc3C)CC2)cn1 +CCCC(=O)Nc1ccc(S(=O)(=O)NC(C)=O)cc1 +CC(C)(Oc1cccc2cccnc12)C(=O)n1ccnc1 +CC(=O)Nc1ccc(NCC(=O)OC(C)C)cc1 +Cn1cc(-c2ncc(C(=O)N3CCOC(C)(C)C3)s2)cn1 +Cc1nc(NCc2ccnc(N(C)C)n2)nc(N(C)C)n1 +Cc1ccn(Cc2nc(-c3ccc(C)c(F)c3)no2)c(=O)c1 +CC(C)NS(=O)(=O)c1ccc2c(c1)CCCN2 +Cc1nc(NCc2ccccc2)sc1C(=O)NC1CCCC1 +Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)NCCC(C)C +Cc1ccc(CN(C)C(=O)c2c(C)n[nH]c2N)cc1 +CNC(=O)c1nc2c(s1)CCN(C(=O)CC(C)C)CC2 +N#CCCN(CCC#N)C(=O)c1cccc(N2CCCC2=O)c1 +O=C(NCCC1CCCCC1)Nc1cnn(CC2CCCO2)c1 +O=C(Cc1ccccc1)Nc1cccc(C(=O)N2CCOCC2)c1 +Cc1ccn2c(=NC(=O)c3ccc(NC(=O)C(C)C)cc3)[nH]nc2c1 +CC(C)NC(=O)COC(=O)c1nn(-c2ccccc2)c2c1CCC2 +COc1ccc(C(=O)Nc2c(-c3ccccc3)nc3ccccn23)nn1 +Cc1nc(C)c(CC(=O)Nc2cccc(C)c2C)c(=O)[nH]1 +O=C(CCOc1ccccc1)Nc1cccc(C(=O)N2CCCC2)c1 +COc1cccc(NC(=O)Cn2ccc(C(F)(F)F)n2)c1 +Cc1ccc(C)c(C(=O)CCC(=O)N2CCC3(CC2)OCCO3)c1 +Cc1ncsc1CCN(C)c1cc(N2CCC(O)CC2)ncn1 +Cc1ccc2c(c1)NCCN2Cc1c(C)noc1C +Cc1nc(C)n(CCN2CC(C)(c3ccccc3)CCC2=O)n1 +CCn1cc(CN2CCOCC2c2ccc(C)o2)cn1 +C=CCN(Cc1ccc(OC)cc1)S(=O)(=O)c1ccc(C#N)cc1 +CCOc1cc(C#N)ccc1OCc1nnc(C2CC2)o1 +OC(c1ccc(Cl)cc1)C1(n2nnc3ccccc32)CC1 +CCOC(=O)c1sc2ncn3nc(-c4ccco4)nc3c2c1C +CCCn1cc2c(c1-c1ccccc1Cl)c(=O)n(C)c(=O)n2C +Cc1cc(-c2ccncc2)c(C#N)c(S(C)=O)n1 +O=C(CCc1ncc(-c2c(F)cccc2F)o1)Nc1ccccn1 +COc1cc(CNc2ncnc3c2CCC3)cc(OC)c1 +CCC(=O)N1CCCC1C(=O)Nc1ccccc1Oc1cccnc1 +CCc1nc(CC(=O)Nc2cc(C)ccc2O)cs1 +CCCCS(=O)(=O)Nc1cnn(Cc2ccccc2)c1 +CCc1nnc(COc2ccc(C(O)CC)cc2)o1 +CCN(CC)c1ccc(NC(=O)c2cc(C3CC3)[nH]n2)cn1 +O=c1ccc(C2NCCc3c(Cl)cc(O)cc32)c[nH]1 +Cc1ccc(SCC(=O)NCC2Cc3ccccc3O2)nc1 +CC(=O)N1CCC(Oc2ccc(-c3ccsc3)cc2)CC1 +CCn1nc(-c2cccc3ccccc23)cc(CO)c1=O +Cc1ccnc(Nc2nc(C)c3cccc(C)c3n2)n1 +COc1ccc(OC)c(NC(=O)CC2Cn3ncnc3NC2=O)c1 +Cc1occc1C(=O)N(C)Cc1csc(C(C)C)n1 +C#Cc1cccc(NC(=O)N2CCN(C(=O)c3ccco3)CC2)c1 +CCc1nc(CN2CCN(C(=O)C3CCC(=O)NC3)CC2)cs1 +CC1(COC(=O)c2ccc(OCC(F)F)nc2)COC1 +Cc1cc(C)nc(-n2ncc3c2CC(c2cccs2)CC3=O)n1 +Cc1c(CCC(=O)NCc2cccc(C(F)(F)F)c2)cnn1C +COc1ccccc1CN(C)C(=O)Cn1c(=O)n(C)c2ccccc21 +COc1ccccc1NC(=O)c1ccc2c(c1)S(=O)(=O)N(C)C2=O +CCCCN(C)c1c(N2CCN(C(=O)OCC)CC2)c(=O)c1=O +CCOCC(=O)N1CCN(CC(=O)NC2CCCC(C)C2)CC1 +CCS(=O)(=O)Nc1ccc(C(=O)NCCC(C)C)cc1 +CCCCNC(=O)N1CCC(c2nc(CCC)no2)CC1 +c1ccc(-c2nc(CSc3nncs3)no2)cc1 +COc1cc(OC)c(C(=O)CCCO)c(OC)c1 +Cc1ccc2c(c1)C(=O)CC(c1cccc(O)c1)O2 +CC(=O)NC1C(Oc2ccccc2C(C)=O)OC(CO)C(O)C1O +Cc1nc2ccc(NC(=O)NC(CCO)c3ccccc3)cc2s1 +CC(C)CNC(=O)CNc1ccccc1Br +Nc1cccc(OCCNC(=O)c2ccncc2)c1 +CN(C)S(=O)(=O)N1CCCC(c2ccncn2)C1 +O=C(Nc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1)C1CC1 +CCn1nc(C(=O)NC(C)(C)c2nc(C)c(C)s2)ccc1=O +O=C(NCc1nnc2ccccn12)Nc1cccnc1 +CCN1CCN(S(=O)(=O)c2cc(Cl)c(N)c(Cl)c2)CC1 +CCS(=O)(=O)N1CCOC(c2ccncn2)C1 +CN(C)S(=O)(=O)NC1(Cc2ccccc2)CCCC1 +O=C(NCCC(=O)N1CCCC1)NC1CCCCC1 +O=C(Nc1ccc2[nH]ncc2c1)c1ccn2ccsc12 +COc1cc(C2NC(=O)c3ccc(Cl)cc3N2)cc(OC)c1OC +CNC(=O)c1sc2nc(-c3ccc(OC)cc3)cn2c1C +CCNC(=O)CNC(=O)Nc1cc(OC)ccc1Cl +CC(O)CCn1ccc2[nH]c(=O)c(C#N)cc2c1=O +CC(=O)Nc1cc(OC(C)=O)c(OC(C)=O)c2ccccc12 +Cc1nc(-n2nnc(C#N)c2-c2cccnc2)sc1C +CSc1cccc(NC(=O)c2cccc(O)c2)c1 +Cc1nn(C)c(C)c1CNC(=O)c1ccc(-n2nnnc2C)cc1 +Cc1ccc(-c2ccc(=O)n(CC(=O)NCCC(C)C)n2)cc1C +Cc1cnc(NC(=O)c2ccc(-c3ccco3)o2)s1 +COC(=O)C(C)Nc1nc2cc3c(cc2[nH]1)OCCO3 +O=c1c2ccccc2nc2ccc(NCCO)nn12 +c1ccc(-c2cnn(Cc3nnnn3C3CC3)c2)cc1 +Cc1cc(NC(=O)CCc2cccnc2)ccc1S(N)(=O)=O +CNc1nnc(-c2cnn(-c3cccc(OC)c3)c2C)s1 +O=C1N=C(N2CCCCC2)CN1c1ccc(Cl)cc1 +Cc1cccn2c(NC(=O)c3ccoc3)c(-c3ccccc3)nc12 +COc1ccc(-c2noc(CCC(=O)Nc3ncc(C)s3)n2)cc1 +NC(=O)CSc1nnc(NC(=O)CCn2cnnn2)s1 +Cc1ccnc2nc(C(=O)NCc3cn[nH]c3)nn12 +Nc1ccc(C(=O)OCc2ccccc2)c(Cl)c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)NC1CCC(O)CC1 +CN(c1cnc2ccccc2n1)C1CCCN(C(=O)OC(C)(C)C)C1 +Cc1cc(Cl)cc2c1N(C(=O)c1ccn(C)c(=O)c1)CCC2 +CCOc1ccc(C#N)cc1NCc1nc(C2CC2)no1 +CC(C)C(=O)N(C)c1ncccc1Br +COCC(=O)NC1CCCN(c2ccnc(C)n2)CC1 +COC(=O)C1CN(Cc2cn(C)nc2C(C)(C)C)CC(C)O1 +COc1ccc(OC)c(CN(C(=O)NC2CCC(O)CC2)C2CC2)c1 +COc1ccc(Cl)cc1Nc1ncnc2c1nnn2C +Cn1ccc(NC(=O)CCC(=O)N2CCSc3ccccc32)n1 +COc1cc(C(=O)Nc2ncc(C(N)=O)s2)ccc1C +Cc1cc(-n2c(C)nc3ccccc3c2=O)ccc1N +O=C(Nc1cc2c(cc1Cl)OCCO2)c1cc(F)cc(F)c1 +Cc1nc2sc(-c3ccc(F)cc3)nn2c1C#N +COCCNC(=O)c1cc(OC)c(Br)c(OC)c1 +COC(=O)c1ccc(Cl)c(N2CCNC(C)C2=O)c1 +CC(=O)NCCNC(=O)Cc1c(Cl)cccc1Cl +FC(F)(F)c1ccc(N2CCC(c3nc4ccccc4[nH]3)CC2)nn1 +CCc1cc(NC(C)c2c(C)nn(C)c2C)nc(N2CCOCC2)n1 +CC(=O)Nc1ccc(F)c(NC(=O)c2ccnc(OC3CCC3)c2)c1 +OC1CCOCC1Cc1ccc(Br)cc1 +CN(C)c1ccccc1C#CCNC(=O)Cn1ccc2ccccc21 +Cc1n[nH]c(C)c1C(=O)N1CCCC1c1ccsc1 +C=CCNC(=O)Nc1ccc(C(=O)NCC)cc1C +CC(NC(N)=O)C(=O)Nc1ccc(C(=O)N2CCCC2)cc1 +COc1cccc(NC(=O)c2coc(NC(=O)c3ccccc3)n2)c1 +COC(=O)c1ccc(CNc2ccc3ncccc3c2)cc1 +COC(=O)CSc1nc2ccccc2c(=O)n1CC(C)C +COC(=O)C(NC(=O)Cc1cc(C)[nH]n1)C(C)(C)C +Cc1ccn(C(=O)CNc2cccc(Cl)c2C)n1 +CN(CC1CCCC1)C(=O)c1cc(C2CC2)nc2c1c(=O)[nH]n2C +CCOC(=O)C(NCC(C)C)c1ccc(F)cc1F +Cc1cc(C(=O)NC2CCCCC2C)nc2c1c(=O)n(C)c(=O)n2C +CCCNC(=O)c1ccc2c(c1)nnn2Cc1ccc(C)cc1 +Cc1cc(C)cc(Oc2ccc(NC(=O)NCCO)cc2)c1 +CC1CN(C(=O)c2ccc3c(c2)NC(=O)CS3)CCO1 +O=C(NC1CCN(C(=O)c2ccco2)CC1)c1cc2cccnn2n1 +O=C(NCc1cccs1)NC1CC(=O)N(C2CC2)C1 +Cc1cc(N2CCCC(O)(C(F)(F)F)C2)nc(-c2ccccn2)n1 +O=S(=O)(Cc1ccc(F)cc1)Nc1cccc(CO)c1 +O=C(Cc1cccs1)NCc1cccc(Cn2ccnc2)c1 +CCOCC1CCCN(C(=O)c2ccccc2OC)C1 +COc1ccc2c(c1)Cc1sc(NC(=O)c3ccco3)nc1-2 +O=C(Cn1cc(-c2nc(C3CC3)no2)ccc1=O)Nc1ccccc1 +NC(=O)C1CN(S(=O)(=O)c2ccccc2F)c2ccccc2O1 +Cc1cccc(N(CCC#N)C(=O)CSc2nnc(C)n2N)c1C +Nc1nccnc1C(=O)Nc1nnc(-c2ccco2)s1 +Cc1cccc(-c2[nH]ncc2CN2CCC(NS(C)(=O)=O)C2)c1 +CC(=O)NC(C)(C)c1noc(C(C)NC(=O)OC(C)(C)C)n1 +CCOc1ccc(S(=O)(=O)Oc2ccccn2)cc1 +Cc1cc(NC(=O)CNc2cccc(F)c2C)n(C)n1 +O=C(CCc1nc(-c2cccnc2)no1)Nc1cnc2ccccc2c1 +CCOC(=O)c1cnc2nc(C(F)(F)F)nn2c1-c1ccccc1 +Cc1c(C#N)cnn1-c1ccc(Oc2ccccc2)cc1 +Cc1ccc(N2CCC(C(=O)NCc3cnc(C)s3)C2=O)cc1 +CS(=O)(=O)N1CC(C(=O)NCCc2ccccc2)C1 +COC(=O)c1ccc(N2CCOCC2)c(NC(=O)c2ccco2)c1 +CC1CCCN(C(=O)c2cc3c(s2)N(C)CCC3)C1 +COCC(C)NC(=O)c1ccc(-c2ccccc2)cc1 +CCn1cc(C(=O)OC(C)c2ccccn2)c(C(C)C)n1 +Cc1nnc2n1CCN(CCC(=O)NC1CCCCC1)C2 +COc1ccc(CN2CC3CN(c4ccc(C#N)cn4)CC3C2=O)cc1 +CCCC(C)(NC(=O)Cc1ccc(F)c(F)c1)C(=O)OC +Cc1cc(C2CCCN2C(=O)c2cc(F)c(F)cc2Cl)on1 +O=C(Cc1c(F)cccc1F)Nc1cc(F)cc(F)c1 +Cc1ccc2nc(C(=O)N3CCOC(c4ccc(F)cc4)C3)cn2c1 +CCc1n[nH]c(-n2ccc3c(c(C)nc4nc(C)nn43)c2=O)n1 +COCC(NC(=O)Nc1ccc(C(C)=O)c(C)c1)c1ccco1 +COc1cccc(C(=O)N2CCc3ccccc3C2)c1O +CCn1ccc(NC(=O)c2cc3occc3n2Cc2ccc(C)cc2)n1 +Cc1cc(C)n2c(SCC(=O)Nc3cccc(F)c3)nnc2n1 +Cc1ccc(C(C)CCN2CCN(C(=O)c3ccc[nH]3)CC2)o1 +CCS(=O)(=O)c1ccc(-c2ncc(N)nn2)cc1 +Cc1nc(Cc2noc(CNC(=O)CC(C)(C)C)n2)no1 +CCC(C)Oc1ccc(NC(=O)C(NC(C)=O)C2CCCC2)cc1 +NC(=O)c1cccc(NC(=O)C2(c3cccc(F)c3)CCOCC2)c1 +COc1cccc2c(=O)c(C(=O)NCc3ccco3)cn(C)c12 +CCOC(=O)C1=C(CNC(C)(C)C)NC(=O)NC1c1ccccc1 +CC1CN(Cc2nc3ccccc3c(=O)n2Cc2ccco2)CCO1 +O=C(CCc1c[nH]c2ccccc12)N1CCCN(c2cccnn2)CC1 +COc1ccc(CN(C)C(=O)c2cccc(N(C)C)c2)cc1F +CCOC(=O)c1c(NC(=O)CC#N)sc(C)c1C +CC(=O)NCc1ccc(C(=O)Nc2ccnn2CC(C)C)s1 +COc1ccc(CNC(=O)CCN2CCOC2=O)cc1 +CC(=O)c1ccc(NC(=O)CNc2cccc(C#N)c2)cc1 +CC(CNS(=O)(=O)c1ccc(C#N)c(Cl)c1)N1CCOCC1 +Cc1ccc(NC2COC3(CCN(Cc4nccs4)CC3)C2)nn1 +O=C(Cc1ccc(F)cc1)N1CCN(C(=O)c2ccccc2F)CC1 +N#Cc1c(NC(=O)COCC2CC2)sc2c1CCCCC2 +Cc1ccc(NC(=O)c2cc3n(n2)CCS3)cc1 +CC1c2ccsc2CCN1Cc1ccccc1N +OCCN(CCO)c1ncnc2scc(-c3ccc(F)cc3)c12 +CC1CCCC(NC(=O)NCc2ccc(N3CCCC3=O)cc2)C1 +N#Cc1cn(Cc2ccc(Cl)cc2)c(=O)[nH]c1=O +O=C(c1ccccc1)N1CCN(Cc2nc3ccccc3o2)CC1 +COC(=O)Cc1ccc(OC(=O)c2cccc3cn[nH]c23)cc1 +CSc1ccc(-c2nc(Cn3cc(C)cn3)c(C)o2)cc1 +Cc1noc(C)c1S(=O)(=O)NCC(O)c1ccc2c(c1)CCO2 +CC(C)c1ccc(C(=O)Cc2cnc3n(C)c(=O)[nH]c(=O)n23)cc1 +O=C(Cc1ccc(Cl)cc1F)NCc1cccnc1 +CC(=O)c1ccc(NC(=O)c2c[nH]c3ccc(Cl)cc3c2=O)cc1 +CCCn1cc(CN2CCc3[nH]c4cc(C)nn4c(=O)c3CC2)cn1 +CC1CC1C(=O)N1CCN(Cc2ccc(Cl)cc2)CC1 +COc1cc(C)c(Cl)cc1C(=O)CCN1CCOCC1 +CC(=O)N1CCC(C(=O)NCc2nc(C)cs2)CC1 +Cn1cc(Br)cc1C(=O)NCC(=O)NC(C)(C)C +CCC1COCCN1S(=O)(=O)c1ccc(C(C)=O)cc1 +N#CC1(NC(=O)c2ccc(F)c(F)c2)CCCCC1 +Cc1ccc(-c2noc(-c3ccc(N4CCOCC4)nc3)n2)cc1 +CCCC(C)NC(=O)CS(=O)(=O)c1cccc(C)c1 +CCN(Cc1cnn(C)c1)S(=O)(=O)N(C)CCC#N +COC(=O)C1CCCN(Cc2cnc(CC(C)C)s2)C1 +CCOc1nccnc1N1CCC(NC(=O)CNC(C)=O)C1 +CC(C)Cc1cc(C(=O)N=c2[nH]c3ccccc3[nH]2)n[nH]1 +COc1ccccc1C(NC(=O)c1ccoc1C)c1nccn1C +Nc1cnc2[nH]nc(-c3ccc(Br)cc3)c2c1 +CCCCC(=O)Oc1ccc2cc(C(=O)NCC)c(=O)oc2c1 +CN(C)S(=O)(=O)c1cccc(C(=O)OCc2ccc(C#N)cc2)c1 +CCc1ccsc1C(=O)NCc1ccc(C)s1 +CC(C)c1ccc(NC(=O)N(C)CCn2cnnc2)c(C(C)C)c1 +CN(CCC1CCCCO1)C(=O)Nc1ccccc1 +N#CCCn1c(-c2cccs2)nc2cc3c(cc21)OCCO3 +CC(=O)NC(C(=O)NCc1ccc(Cl)cc1Cl)C(C)C +COCCCCC(=O)N(C)c1ccccc1S(C)(=O)=O +Cc1nc2c(c(=O)[nH]1)CCN(Cc1cccc(F)c1)CC2 +CCC(C)NC(=O)CC(NC(C)=O)c1ccccc1 +Nc1nc(C2CC2)ncc1C(=O)N1CCCc2ccccc21 +CCc1ccccc1NS(=O)(=O)c1ccc(OC)c(C(=O)NC)c1 +Cc1ccc(NC(=O)C(C)NC(=O)Nc2ccccc2)cc1C +COC(=O)c1cc(-c2ccc(OC)cc2OC)nn1C +Cn1ccnc1COC(=O)C1CCc2cn[nH]c2C1 +CC(C)NS(=O)(=O)c1ccc(C(=O)Nc2ccccc2)cc1 +CCOCc1ccc(NC(=O)Cc2c(F)cccc2F)cc1 +CSc1nnc(SCC(=O)NCc2cccs2)s1 +CNC(=O)NCC(=O)Nc1ccc(SC2CCCC2)cc1 +Cc1cnc(C(=O)N(C)Cc2cccc(Cl)c2)cn1 +O=S(=O)(NCCCO)c1cccc2ccccc12 +Cc1nc(C)n(CC2CN(C3CC(C)OC3=O)CCO2)n1 +CC(C)c1csc(NC(=O)N2CCN(C(=O)C3CC3C)CC2)n1 +O=C(NCc1ccccc1Cl)c1nc2ncccn2n1 +Cc1cccc(Nc2nc(C(=O)NCC(N)=O)cs2)n1 +Cc1sc(=O)n(CC(=O)NCc2nc3ccccc3[nH]2)c1C +CCc1cccc(C)c1NC(=O)NC(C)COC +COc1ccc(C(=O)CCC(=O)N(C)Cc2ccccc2)cc1 +COc1cc(C)c(C(=O)NCc2nc(C)c(C)s2)cc1OC +O=C(NCCCC(=O)N1CCCC1C1CCCC1)c1ccc(F)cc1 +CNC(=O)CNC(=O)C1(C)Sc2ccccc2N(C)C1=O +CC(C)(C)OC(=O)N1CCCC(Sc2cc(C#N)ccn2)C1 +COc1ccc(CC(=O)Nc2ccc(Cl)cn2)cc1OC +N#Cc1ccc(Oc2cccc(C(=O)NC3CC3)c2)cc1 +COc1ccc(F)c(NC(=O)CCc2ccc(C)o2)c1 +Cc1ccc(C)c(OC(=O)CCCNC(=O)C2CC2)c1 +Cc1nc(SCC(=O)NCC(F)(F)F)c(C#N)c(C)c1C +COC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1ccc(OC)c(OC)c1 +Cc1cccc2c1NC1(NC2=O)C(=O)N(C(C)C)c2ccccc21 +CCCCn1nnnc1CN1c2cccc3cccc(c23)S1(=O)=O +CCOc1ccc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)nn1 +CC(=O)Oc1cccc(-c2csc(-n3nc(C)cc3C)n2)c1 +CCn1c(COc2ccccc2)nnc1SCC#N +Nc1ccc2nnc(-c3cc(F)ccc3Br)n2c1 +CS(=O)(=O)N(CC(N)=O)c1cc(Cl)c(Cl)cc1Cl +COC(=O)c1c(C)[nH]c(C(=O)NCCc2ccc(OC)cc2)c1C +COc1cc(C(=O)OCc2nc(C)no2)cc(OC)c1C +COc1ccc(C(=O)NCC(C)Cn2nc(C)cc2C)cc1OC +CC(C)CNC(=O)C1CCCN(S(=O)(=O)c2cccs2)C1 +Cc1ncsc1CNC(=O)N1CCOC(Cc2ccccc2)C1 +CCOC(=O)CSc1nnc2c3cc(OCC)ccc3n(C)c2n1 +CCOc1cc2c(cc1NC(=O)C1CCC1)OC(C)C2 +CCCc1ccc(OC(C)c2nc(-c3nonc3N)no2)cc1 +COCc1cccc(NC(=O)NC(C)c2nnc3n2CCCCC3)c1 +O=C(Cc1ccc[nH]1)NCCc1nc2ccc(F)cc2[nH]1 +Cc1cc(Cl)ccc1-n1nnc(CO)c1C1CCCO1 +Cc1cc(NC(=O)c2ccc(C(C)C)cc2)ccn1 +CCOc1ccccc1CCC(=O)NC(C)c1ccncc1 +N#Cc1ccc(CN2CCC(Oc3ccccc3)CC2)c(F)c1 +CCc1cc(NC(CO)Cc2c[nH]c3ccccc23)ncn1 +CC(=O)NCCCCCC(=O)Nc1ccc(C#N)cc1 +CCc1ccc2ncnc(NCc3ccncc3)c2c1 +CC(C)C(=O)Nc1cccc(NCc2nnnn2-c2ccccc2)c1 +N#Cc1ccccc1N1CCCN(C(=O)c2n[nH]c3ccccc23)CC1 +Cc1c(F)ccc2c1C(c1ccc(F)nc1)NCC2 +O=C(c1ccc2c(c1)COC2)N1CCCC(n2cccn2)C1 +N#Cc1cccc(N2CCC(CO)(CCCc3ccccc3)CC2)n1 +O=C(CNC(=O)c1ccc(F)cc1)NCc1ccco1 +CCSc1nnc2n(CCCOC)c(=O)c3ccccc3n12 +COc1ccc(CNc2ccc(CN3CCCC3=O)cc2)c(OC)c1 +CC1c2cccn2CCN1C(=O)CCC(=O)c1ccc2c(c1)CCC2 +COc1ccc(NC(=O)CSc2nccc(C)n2)c(OC)c1 +CC(=O)NCCc1ccc(-c2csc(NC3CC3)n2)cc1 +CCCCN(C)C(=O)Nc1cc(C(=O)NC)ccc1OC +COc1ccc(-c2cnn3cc4c(nc23)CCCC4=O)cc1 +COC(=O)c1cc(OC)c(OC)cc1NC(=O)c1ccoc1C +CC(OCC(F)(F)F)C(=O)N1CCN(c2ccc(C#N)cn2)CC1 +N#Cc1ccccc1-c1ccccc1C(=O)Nc1ncc(C(N)=O)s1 +Nc1nccnc1C(=O)NCc1cccnc1-n1cccn1 +Cc1c(C(C)Nc2ncnc3[nH]cnc23)cnn1-c1ccc(F)cc1 +CCN(C)S(=O)(=O)c1csc(C(=O)NC2CCCC2)c1 +Cc1cc(C)n(-c2ccc(=O)n(C(C)C(=O)N3CCOCC3)n2)n1 +CN(C)c1cccc(OC2CCN(C(=O)OC(C)(C)C)CC2)c1 +Cn1nc(C(=O)N2CCCCC2)cc1OCC(=O)N1CCCCC1 +O=C(c1csc2ccccc12)N1CCN(c2ccccc2F)CC1 +CCS(=O)(=O)N1CCN(C(=O)CN(C)C(=O)OC(C)(C)C)CC1 +CC(NC(=O)c1ccc(=O)n(CCOc2ccccc2)n1)C1CC1 +N#Cc1ncn(CC(=O)Cc2c(F)cccc2Cl)n1 +CCn1nc(C)c(NC(=O)Cc2ccc(OC)cc2)c1C(N)=O +COc1cc2c(cc1OC)CN(C(=O)c1cc(C)cc(C)c1)CC2 +CCCCNC(=O)c1cc2c(C)nn(C)c2nc1N +Nc1ccc(F)c(F)c1N1CCOC2CCCC21 +CCOc1ccccc1NC(=O)c1ccc(F)c(F)c1 +Cc1ccnn1CCCNC(=O)Nc1cccc2ccccc12 +CN(C(=O)c1ccc(Cl)c(F)c1)c1ccc(C(N)=O)cc1 +Cc1nnc(NC(=O)NC23CC4CC(CC(C4)C2)C3)s1 +Cc1ccc(CC(=O)NCC#Cc2ccccc2)cn1 +COC(=O)Cc1c(C(=O)OC)nnn1-c1ccc(Cl)cc1 +CC(Sc1ccccn1)C(=O)NCC(=O)c1ccccc1 +CCOc1ccc(-n2nc(C)c(Br)c2C)cc1 +Cc1nc2c(C(N)=O)cnn2c(C)c1CCC(=O)Nc1cnn(C)c1 +CCc1nnc(-c2cc(NC(=O)C3CC3)c(C)s2)o1 +Nn1cnc2c(c1=O)C1(CCCC1)Cc1ccccc1-2 +N#CCCN(C(=O)Cc1ccc(Br)cc1)C1CC1 +O=C(NCC(=O)N1CCN(CCO)CC1)c1ccccc1 +Cc1cccc(NC(=O)Cn2nc(-c3ccc(F)cc3)ccc2=O)n1 +Cc1cc(CN2CCN(C(=O)NCc3ccncc3)CC2)on1 +Cc1cc(-c2ccc3c(c2)C(C)(C)C(=O)N3)nc(N)n1 +COc1cc(C(=O)NCc2ccc(-c3csc(C)n3)o2)ccc1C +Cc1n[nH]c(C)c1NC(=O)c1cccc(S(=O)(=O)NC(C)C)c1 +COc1ncccc1C(=O)Nc1ccc(F)cc1Br +Cc1ccnn1-c1ccc(C(=O)N2CCNC(=O)C2C(C)C)cc1 +CC(=O)Nc1ccc(CC(=O)Nc2ccc(C)cc2C)cc1 +CCNC(=O)NCC1COCc2nc3cc(OC)ccc3n21 +CCC(NC(=O)c1c(F)c(F)cc(F)c1F)C1CCOCC1 +CC(=O)Nc1cccc(NCC=Cc2ccc(C#N)cc2)c1C +Cc1cccc(NC(=O)CCC(=O)c2cccs2)c1 +CCCCc1nc2ccc(OCC(C)O)cc2s1 +COC(=O)C1=C(C)N(C2CC2)C(=O)NC1c1cccc(F)c1 +Cc1csc(CNc2cccc(N3CCNC3=O)c2)n1 +CNC(=O)Cc1ccc(NC(=O)c2ccccc2OC(C)C)cc1 +COC(=O)c1cccc(S(=O)(=O)N=c2ccc(C)c[nH]2)c1 +O=C(CNc1ccccc1Cl)NCCc1ccco1 +Cc1ccc(N(C)C(=O)c2cc(S(C)(=O)=O)ccc2C)c(C)c1 +CC(=O)N1CCC(c2ccc(Br)cn2)CC1 +Nc1cnn(CCCc2ccc3c(c2)CCCC3)c1 +Cc1cccc(C(=O)NCCC(=O)NCc2ccccc2Cl)c1 +Cc1cnn(CCCCCn2c(S(C)(=O)=O)nc3ccccc32)c1 +O=C(NCCSc1ccc(Cl)cc1)c1ccc(O)nc1 +Cc1ccc(C(=O)Nc2ccc(C#CCO)cc2)s1 +O=C(c1cc2c(s1)CCCC2)N1CC=CC1CO +COc1ccc(C)cc1NC(=O)C1CCCN(c2cnccn2)C1 +COc1ccc(Br)cc1C(=O)CCCC#N +COc1cc(OC)cc(C2CCN(C(=O)c3cc[nH]c3C)C2)c1 +Cc1cccc(CCCOC(=O)c2ccccc2F)n1 +Cc1cc2c(c(=O)[nH]1)C(c1ccncc1)CC(=O)O2 +Cc1ccc(C(=O)NCCC(O)c2ccco2)c(C)c1 +COc1ccc(N(Cc2ccccc2)C(=O)C(C)n2cncn2)cc1 +CCc1cc(NC(=O)c2ccnc(OC3CCC3)c2)nc(C)n1 +O=C(COc1ccc(F)cc1)N(Cc1ccco1)Cc1cccs1 +N#Cc1nnn(-c2cccc3ccccc23)c1C1CCCO1 +CCC(=O)Nc1ccc2c(c1)CN(C(=O)C1CC1)CC2 +CSc1nc(C(=O)Nc2c[nH]ccc2=O)c2ccccn12 +C=CCNC(=O)c1cccc(S(=O)(=O)Nc2c[nH]nc2C)c1 +CC(=O)c1c(C)[nH]c(C(=O)N(C)C(C)C(C)(C)C)c1C +Cc1nc(CNc2nc3nonc3nc2NC2CC2)cs1 +COc1ccc(C(=O)N2CCc3n[nH]c(-c4ccccc4)c3C2)cc1 +CCOc1ccc(CC(=O)N2CCN(Cc3ccsc3)CC2)cc1 +Cn1cc(C(=O)N2CCN(C(=O)N3CCOCC3)CC2)ccc1=O +CC(=O)c1cccc(NC(=O)C(C)OC(=O)c2ccc(F)cc2F)c1 +CCc1nnc(-c2ccc(=O)n(CC(=O)Nc3ccc(F)cc3)c2)o1 +O=C(CC(F)(F)F)N1CCN(Cc2cc3cc(F)ccc3o2)CC1 +Cc1noc(C)c1C(C)NC(=O)N(CCC(N)=O)Cc1ccccc1 +O=C1C(Nc2c(F)cccc2-n2cccn2)CCN1C1CC1 +O=C1CC2(CCCCN2C(=O)c2ccoc2)CN1Cc1ccccc1 +O=C(Nc1ccccc1Cn1cccn1)c1ccc(Cl)cc1 +COCCNc1cc(-c2cc(OC)nc(N)n2)c2cc[nH]c2n1 +O=C(c1cccc2ccnn12)N(Cc1ccccn1)CC1CCCO1 +CCc1nonc1NC(=O)c1cc2ccccc2oc1=O +COc1cc(-c2nc3c(N)cccn3n2)ccc1O +Cc1nnc2n1CCN(CC(=O)NCCc1ccsc1)C2 +CC(NC(=O)C1CCN(C(=O)OC(C)(C)C)CC1)c1cccs1 +CCOCCNC(=O)c1cc(S(N)(=O)=O)ccc1C +CCN(CCO)c1cc2nc(C)sc2cc1N +CN(C)C(=O)CCOc1ccc2ccc(O)cc2c1 +Cc1cccc(OCCNC(=O)Cc2cccs2)c1 +CCn1cnnc1CNC(=O)c1cc(Br)ccc1Cl +O=C(Cn1nc(-c2cccs2)n(C2CC2)c1=O)NC1CCCCC1 +Cc1cccc(CC(=O)NCc2nnnn2C2CCCCC2)c1 +Cc1ccc(C)c(OCC(=O)Nc2c[nH]c(=O)[nH]c2=O)c1 +O=C1CCCc2[nH]c(=O)c(C(=O)OC3CCCC3)cc21 +CC(=O)Nc1cccc(NC(=O)C2COc3ccc(Cl)cc3C2)c1 +FC(F)(F)c1nnc2ccc(NCC3CCC3)nn12 +N#Cc1cnc(SCCc2ccncc2)nc1N +Cc1ccc(C(=O)c2cc(N)ccc2OC(F)F)cc1 +O=C(c1cc(-c2csc(Cc3ccccc3)n2)c[nH]1)N1CCCC1 +CCNC(=O)COc1cccc(NC(C)c2nnc(C)o2)c1 +O=S(=O)(c1ccc(F)cc1)C1CN(S(=O)(=O)c2c[nH]cn2)C1 +CNC(=O)C1CCC(NC(=O)Nc2nc(C)cs2)CC1 +O=C(c1cc2c(s1)CCC2)N1CCCCC1Cn1cccn1 +O=C(c1ccc(-n2ccnn2)cc1)N1CCN(c2ccccc2O)CC1 +CSc1ccc(Cl)cc1NC(=O)c1cnn(C)c1C +O=C(c1c(F)cccc1F)N1CCN(C(=O)C2CCCO2)CC1 +Cc1ncc(Cn2c(CO)nc3cc(N)ccc32)s1 +COc1ccccc1OCc1cc(C(=O)N(C)C(C)C)no1 +Cc1ccccc1CNC(=O)C(C)Sc1ccc(O)cc1 +CC(C)OCC(=O)Nc1c(Cl)cc(N)cc1Cl +Nc1c[nH]c(CCc2ccccc2Br)c1 +Fc1ccccc1-c1cc(NC2CC2)nc(-c2ccccn2)n1 +COC(=O)CNC(=O)CCSc1ccc(F)cc1 +COc1ccccc1-n1cc(C(=O)N2CC3CCCC3(CO)C2)cn1 +COc1cccc(CNC(=O)C(C)Sc2ncc3ccccn23)c1 +COc1cccnc1-c1cnn(CC(=O)Nc2cc(C)nn2C)c1 +COC1(CNC(=O)c2ccc(-n3ccnn3)cc2)CCOCC1 +Cc1ccc(C)c(OCCCSc2nnc(C)c(=O)n2N)c1 +COCCN1CCN(C(=O)c2ccccc2C(C)(C)C)CC1=O +CCOc1ccccc1NC(=O)CSc1nncn1C(C)C +Cc1cnc(N2CCC3(CC2)CC(=O)N(C)c2ccccc23)nc1 +CC1(C(=O)NCc2ccccc2)CCC(=O)N1Cc1ccccc1 +CC(C)c1n[nH]c(C2CN(C(=O)C3CCc4ccccc43)CCO2)n1 +CCOc1ccc(C(=O)NCc2cc3ccccn3n2)cc1OCC +COc1ccc(NC(=O)NCC(C2CCOC2)N2CCOCC2)cc1 +C=CCNC(=O)c1cccc(S(=O)(=O)N(C)Cc2cc(C)on2)c1 +Cc1csc(C2CCCCN2C(=O)CC2CCc3ccccc32)n1 +CCOC(=O)CSc1nc(-c2ccccc2)ccc1C#N +CCC(C)N(CC)C(=O)Cn1cc(N)ccc1=O +O=C(Cn1ncccc1=O)Nc1cc(F)ccc1F +COc1cc(C(=O)N(C2CCCCC2)C2CC2)ccc1OCC(N)=O +Cc1cc(C)cc(NC(=O)c2c(C)c(N)c(C)[nH]c2=O)c1 +O=C(CC1C=CCC1)N1CCn2c1nc1ccccc12 +O=C1c2ccccc2C2(c3ccccc3)NCCCN12 +CNc1nc(C(=O)NC(c2ccncc2)c2ccc(F)cc2)cs1 +CCOc1ccc(S(=O)(=O)NCc2ncn(C)n2)cc1 +CC(=O)c1ccc(NC(=O)CCNC(=O)c2ccco2)cc1C +CCOCCNC(=O)NCCc1ccccc1C +CCOC(=O)CCC(C)NC(=O)c1ncoc1C +CC(=O)Nc1cccc(OCCNC(=O)Nc2cc(C)nn2C)c1 +CC(C)(C)C(=O)N1CC2c3ccccc3OCC2(CO)C1 +O=C(NCc1cccc(Cn2cccn2)c1)NC1CCCC1 +Cc1cccc(C)c1OCCN1C(=O)c2ccccc2S1(=O)=O +COc1cccc(-c2nnn(CC(O)c3ccccc3)n2)c1 +Cc1ccc(N2CCN(C(=O)c3cccc(F)c3)CC2)c(C)c1 +CCN(CC)S(=O)(=O)Nc1c(N)ccc(C)c1C +CSc1ccc(NC(=O)C2CCCN(C(N)=O)C2)cc1 +COCCNc1ncnc(Oc2ccc(Cl)c(C)c2)c1N +O=C(Nc1ccc(Cl)cc1)Nc1nnc(-c2ccsc2)o1 +N#Cc1cn(C2OC(CO)C(O)C2O)c(=O)nc1N +CC(=O)NC(C)(C)c1noc(-c2cccc(N3CCCC3=O)c2)n1 +Cc1nc(COc2ccc(C(=O)NCCCO)cc2)cs1 +OC(Cc1nc2ccccc2[nH]1)c1nc2ccccc2[nH]1 +CCCOC(=O)Cn1nc(C#N)cc1-c1ccncc1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)c1ccccc1 +CCc1ccc(OCc2nc3cc(N)cnc3o2)cc1 +CC(Nn1cncn1)c1ccc(Cl)cc1Cl +Cc1ccccc1CCNC(=O)CS(=O)(=O)c1ccccn1 +O=C(CCN1C(=O)c2ccccc2S1(=O)=O)NCCc1ccco1 +CC1=NC(C#N)N(C(=O)c2ccccc2)c2ccccc21 +COc1ccc(-c2noc(CC(C)C)n2)cc1OC +CC1CN(C(=O)COC(=O)c2ccc(O)cc2O)CC(C)O1 +C=CCn1c(C)cc(C(=O)COc2ccc(-c3nnco3)cc2)c1C +CC1CC(OC(=O)C2CCN(C(=O)Nc3ccccc3)CC2)C(=O)O1 +CC(=O)N1CCC(C(=O)Nc2cnccc2Oc2ccccc2)CC1 +CN(C)c1cccc(C(=O)NCCn2ccc(-c3ccncc3)n2)c1 +CCSc1ccc(C(=O)NCCS(=O)c2ccccc2)cn1 +CC1CN(C(=O)c2ccnc(OC3CCC3)c2)CC(C)O1 +COC(=O)Cc1csc(NC(=O)c2cc(-c3ccncc3)on2)n1 +O=C(Nc1nc(-c2cccs2)cs1)c1cccs1 +OCCC1CCCCN1c1cc(C(F)(F)F)nc2ncnn12 +Cc1sc2ncnc(NCCC(=O)N3CCCC3)c2c1C +Cc1noc(-c2ccc(SCC(=O)NCc3ccncc3)nc2)n1 +O=C(NCCOc1ccccc1)c1ccc(=O)n(Cc2ccccc2)n1 +Cc1ccc(CCN(C)C(=O)C(N)c2ccccc2)cc1 +CCOCC1CCCN(C(=O)c2cnc(Cc3ccccc3)s2)C1 +CCC(C)C(C)NC(=O)Cc1cc(OC)ccc1OC +O=C(NC1CCCCC1)c1ncc(-c2ccncc2)s1 +O=C1CCc2ccccc2N1Cc1nc(-c2ccsc2)no1 +CC1CCN(C(=O)C(C)OC(=O)c2cccc(O)c2)CC1 +CC(=O)Nc1ccc(S(=O)(=O)NCC(C)C#N)cc1 +O=C(NCC1(c2ccc(F)cc2F)CC1)Nc1ccncc1 +N#CCOc1cccc(CC(=O)NC2CC=CC2)c1 +CSc1cccc(NC(=O)CNc2ccc(C#N)cc2)c1 +CC(NC(=O)C1CC=CC1)c1cc(F)ccc1N1CCC(O)CC1 +CC(=O)Nc1ccc(S(=O)(=O)CCC#N)cc1 +CC(=O)Nc1nc(NC(C)=O)nc(N2CCOCC2)n1 +CC1CN(C(=O)c2n[nH]c(C(C)C)c2N)CCO1 +CCS(=O)(=O)NCc1ccccc1C#CCO +COCc1nc2ncc3c(=O)n(Cc4cccnc4)ccc3n2n1 +O=C(COCC(F)(F)F)Oc1ccc(Cl)cc1Cl +Cc1noc(C)c1C(C)NC(=O)NCC(=O)N1CCCCC1 +OCC1CCCN(c2ccc3nnc(-c4ccccc4)n3n2)C1 +CCNC(=O)c1cccc(NC(=O)N(C)Cc2ccc(C#N)cc2)c1 +Cc1c(C(=O)OCC(C)C)sc2nc(-c3cccnc3)[nH]c(=O)c12 +Cc1ccc(-c2n[nH]c(NC(=O)c3ccoc3C)n2)cc1 +CCC1CN(C(C)C(=O)OC)c2cc(C(C)=O)ccc2O1 +C#CCC(NC(=O)c1ccc(OCC(F)F)nc1)C(N)=O +CNC(=O)COc1ccccc1-c1nc(-c2cccc(C)c2)no1 +CCCC(NC(=O)Cc1ccccc1)C(=O)N1CCOC(C)(C)C1 +CCN(CC)C(=O)CCCNC(=O)Nc1cn[nH]c1 +CC(C)C(NC(=O)c1ccccc1)C(=O)NCc1ccco1 +Cc1csc(NCc2ccc(Cl)c(F)c2)n1 +CC(C)(C)CCS(=O)c1nc2ccc(N)cc2[nH]1 +CN(CC(=O)Nc1ccn(Cc2ccccc2)n1)C(=O)c1ccccc1 +CCNc1nc2c([nH]1)c(=O)n(CC)c(=O)n2CCCOC +CN(C)C(=O)Nc1ccc(S(=O)(=O)NCC2CCCO2)cc1 +CC(CCc1ccccc1)NC(=O)C1CN(S(C)(=O)=O)C1 +CC(=O)Oc1ccc(C(=O)Nc2cccc(C)c2C)cc1 +Cc1nc2sc(-c3ccccc3F)nn2c1CO +CCC(NCc1cncs1)c1ccc(Cl)cc1 +O=C(NC1CC1)OCC(O)C1COc2ccccc2O1 +Cc1nonc1NC(=O)c1c(-c2ccccc2)noc1C +CC(C)(C)c1nnc(SCc2ccc(F)cc2)n(N)c1=O +C=C(C)n1c(=O)n(CC(=O)N2CCC(C)CC2)c2cc(C)c(C)cc21 +Cn1ncc2c(N3CCCC(CCC(N)=O)C3)nc(C(C)(C)C)nc21 +CC(=O)Nc1cccc(CNC(=O)Nc2ccc(F)cc2C#N)c1 +CCc1cc(=O)[nH]c(-n2nc(C3CC3)cc2NC(=O)C2CCCC2)n1 +COCCCNC(=O)CN(C)C(=O)c1ccc(F)cc1 +CC(Sc1nnnn1C1CC1)C(=O)Nc1sccc1C(N)=O +O=C(CSc1nncs1)NC1CCc2c(F)cccc21 +COc1cc(OC)c(C(=O)NC(C)C2CCCO2)cc1OC +CCc1cc(=O)n(CCNC(=O)c2cc(=O)[nH]c(=O)[nH]2)cn1 +CN(C(=O)c1nn(C)c2ccc(Cl)cc2c1=O)c1ccccc1 +CSc1ccc(NC(=O)NCc2cnn(C)c2C)cc1F +Cc1cc(NC(=O)c2ccc(F)cc2)c2ncccc2c1 +COC1CCCN(C(=O)Cc2csc(-c3cccs3)n2)C1 +COc1ccc(CNC(=O)C2c3ccccc3CC(=O)N2C)cc1 +CC(c1nc(N)nc(N(C)C)n1)N1CCC(C(=O)N(C)C)CC1 +CCCCC(C)NS(=O)(=O)c1ccc(O)c(N)c1 +Cc1ccnc(NC(=O)c2cc(C(C)C)nc(N3CCCC3)n2)c1 +NC(=O)C1CCN(C(=O)c2occc2CSc2ccccc2)C1 +CCNC(=O)Nc1ccc(-c2nc3ccccc3[nH]2)cc1 +CN(C)c1cccc(COC(=O)c2ccc(-n3ccnn3)cc2)c1 +CCCOC(=O)CCSc1ccc2c(c1)OCCCO2 +O=c1c2sc(N3CCOCC3)nc2ncn1Cc1cccc(F)c1 +CCOC(=O)CNC(=O)c1cc(F)c(F)c(F)c1F +O=C(Cc1cccc(O)c1)NC1(c2ccc(F)cc2F)CCOCC1 +CC(C)(O)c1cn(CC2CCN(c3ccc(C#N)cn3)CC2)nn1 +Cc1ccc(NCC(O)c2ccc(F)c(F)c2)cc1 +CC(C)NC(=O)COC(=O)CN(C)C(=O)c1ccccc1 +O=C(Cn1nc2ccccn2c1=O)N1CCCC1C1CCCC1 +Cc1ccc(CNC(=O)Cc2nc3ccc(N)cc3o2)cc1 +CC(NC1=NS(=O)(=O)c2ccccc21)C(=O)Nc1cnn(C)c1 +Cc1cc(NC(=O)c2ccc3ccccc3c2)[nH]n1 +CCOC1CC(NC(=O)C(C)OCC2CCCCO2)C12CCCC2 +CC(C)(CO)NS(=O)(=O)c1ccc(C(=O)Nc2ccccc2)cc1 +COC(=O)C(C)CNC(=O)c1cccc(Br)c1Cl +CCOCCn1c(COC)nc2cc(Cl)ccc21 +CC(=O)Nc1ccc(NC(=O)CNC(=O)c2cccs2)cc1 +Cc1cc2occ(CC(=O)NCC(N)=O)c2cc1C +CS(=O)(=O)N1CC2OCC(=O)N(Cc3cccnc3)C2C1 +CNC(=O)C(CC(C)C)NC1=NS(=O)(=O)c2ccccc21 +Nc1nc(=O)n(C2OC(CO)C(O)C2O)cc1Br +CCOC(=O)NCCNC(=O)c1cccc(Br)c1C +O=C(CCC(=O)c1cccs1)NCCc1ccccc1F +CC(=O)N1CCCc2cc(NC(=O)NC(C(N)=O)C(C)(C)C)ccc21 +COc1ccc(NC(=O)c2cn(C)c3ccc(F)cc3c2=O)cc1 +Cc1ccc(CC(=O)Nc2nnc(-c3cccnc3)o2)c(C)c1 +COC(=O)c1cc(CNc2ccc(F)cc2OC(F)F)c[nH]1 +CNC(=O)NCC(=O)Nc1ccccc1-c1nc2ccccc2s1 +Cc1cc(C(=O)NCCCO)cc(C)c1OCc1cccnc1 +Cc1noc(C)c1CC(=O)N(Cc1cnc2ccccn12)C1CC1 +CCCCn1nccc1NC(=O)c1nccnc1N +COc1ccc(CN(C)Cc2nc3ccccc3s2)c(OC)c1 +CCn1c(C)nnc1SCC(=O)Nc1ccccc1 +O=C(Nc1cccnc1)c1cc2c(s1)CCCC2 +CCCS(=O)(=O)N(Cc1ccc(CC)cc1)C1CC1 +CC(C)n1ncc2cc(NC(=O)CCCc3cccs3)cnc21 +Nc1nc(N)c2c(n1)CCc1c(Cl)cc(Cl)cc1-2 +Cc1ccc(CSc2nnc(CNC(=O)c3ccccc3)o2)cc1 +CC(C)CCC(=O)NCc1nc(Cc2ccc(Cl)cc2)no1 +CC(C)Cc1c(C#N)nnn1Cc1ccc(F)cc1 +CCC(CC)NC(=O)COc1ccc(C)c2c1C(=O)CC2C +COc1ccc(C(=O)N(C)Cc2sccc2C)c(OC)c1 +CCNC(=O)c1ccc(CNC(=O)c2ccc(F)cc2)cc1 +COc1ccc2c(c1)C(O)C(N(C)Cc1ccccc1)CO2 +CC(C)CCOc1cc(N)c(N)cc1Br +c1ccc(-c2csc(CN3CCOC4(CCC4)C3)n2)cc1 +CC1CCN(C(=O)CN(C)c2ccc(N)cn2)CC1 +Cc1noc(C(C)OC(=O)c2cnn(-c3ccccc3F)c2C)n1 +CCN(CC)C(=O)CCc1c(C)nc2c3ccccc3nn2c1C +CCc1ccc(-c2nc(SCc3nnc(CC)o3)n[nH]2)cc1 +c1cnn(-c2ccc(CSc3ncnc4sccc34)cc2)c1 +CC(C)(NC(=O)c1scnc1C1CC1)c1ccc2c(c1)OCO2 +O=C(NCCOc1ccc(Cl)cc1)c1cnn[nH]1 +CCOC(=O)CNC(=O)CCc1c(C)nn(C)c1C +Cc1ccccc1-n1cc(C(=O)NC2CC2C)cn1 +CC1CN(C2(C(=O)N3CCC(O)C3)Cc3ccccc3C2)CC(C)O1 +CCOC(=O)Nc1ccc(NC(=O)NCc2ccc(F)cc2)cc1 +CCN(CC)C(=O)c1cnc(-c2ccccc2C)nc1N +Cc1cc(C(=O)NC2CCCC2)ccc1NC(=O)NCCO +O=C(c1cn[nH]n1)N1CCN(Cc2cccc3nonc23)CC(O)C1 +CCOC(=O)C(C)NC(=O)c1c(O)cc(F)cc1F +Cc1ccc(NC(=O)CC2Cn3ncnc3NC2=O)cc1C +COC(=O)C(C)Oc1ccc(CN2CCOC(C#N)C2)cc1 +CCOC(=O)c1cc(S(N)(=O)=O)ccc1OCC +Cc1ccc2cccc(Nc3ncnc(NCCC(C)C)c3N)c2n1 +Cc1c(C(=O)N2CCN(C(=O)c3ccccc3)CC2)oc2ccccc12 +COc1ccc(-c2nc(CNC(=O)c3ccccn3)n[nH]2)cc1 +Cc1noc(C)c1S(=O)(=O)Nc1ccc(NC(=O)C(C)C)cc1 +O=C(CCc1ccccc1F)NCc1ccc(-n2ccnc2)cc1 +OC(CN1CCOC2CCCCC21)Cn1cccn1 +NC(=O)c1ccc(NC(=O)c2cccc(Nc3ncccn3)c2)cc1 +O=C(CCc1cc(Cl)cs1)NCCC(=O)NC1CCCC1 +CC(NC(=O)CSc1nnnn1C(C)C)c1cc2ccccc2o1 +Fc1ccc(CN2CC(c3nc(-c4cnccn4)no3)C2)cc1F +CC(CO)NC(=O)c1ccc(F)c(S(=O)(=O)NC(C)(C)C)c1 +Cc1ccccc1NC(=O)c1nn(-c2ccccc2F)c(C)cc1=O +O=C(NCCC(O)c1cccc2ccccc12)c1ccsc1 +CN(C)C(=O)C(Sc1ccccc1F)c1ccccc1 +CCC(CC)N(CCO)C(=O)c1cccn1C1CC1 +CC(C)(C)OC(=O)Nc1cccc2[nH]cc(CO)c12 +Cc1ccc(-c2nc(NC(=O)CSc3n[nH]c(N)n3)ns2)cc1 +C=CCn1cc(-c2cc(-c3cn(CCC)nc3C)nc(N)c2C#N)cn1 +Nc1nc(SCc2nnc(C3CCCO3)o2)n[nH]1 +Cc1cc(C(C)(O)CNC(=O)c2cc(C3CC3)on2)c(C)o1 +O=C(CN1C(=O)OCC1c1ccccc1)N1CCOC2(CCCC2)C1 +O=C(c1scnc1C1CC1)N1CCOC2CCCCC21 +CC(=O)NC(C)C(=O)N1CCC(c2nc3cc(Cl)ccc3o2)CC1 +Cc1ccc(C)c(SCC(=O)Nc2cccc(O)c2)c1 +CCCCc1ccc(N2CC(C(N)=O)CC2=O)cc1 +O=C(CCn1cccn1)NC1CCN(c2ccc(F)c(Cl)c2)C1 +O=C(C1CCCO1)N1CCc2ccc(=O)n(CC3CC3)c2CC1 +NC(=O)CN(C(=O)c1ccc(Cl)c(Cl)c1)c1ccccc1 +CCN(CC(=O)NC(C)(C)C)C(=O)NCC(=O)NC(C)(C)C +CCC(CO)N1CCN(C(=O)Nc2cc(F)ccc2OC)CC1 +Nc1c(Nc2nccs2)ncnc1Nc1ccc(F)cc1F +Cc1c(Cl)cccc1NCc1nc(C(F)(F)F)cc(=O)[nH]1 +Cc1cnc(=O)n(Cc2sccc2C#CCCO)c1 +CCCOc1ccc(CNC(=O)c2ccc(F)nc2)cc1OC +CC(Sc1nnnn1C1CC1)C(=O)NC1(C)Cc2ccccc2C1 +CN(Cc1nc(-c2ccco2)no1)c1ccccc1 +Fc1c(Cl)ccc2c1CCNC2c1ccc[nH]1 +CCN1CC(C(=O)NCc2ccccc2Cn2cccn2)CC1=O +Cc1ccc(CNC(=O)N(C)Cc2cnn(C)c2)c(N(C)C)c1 +Cc1cc(Nc2cnn(CCN3CCOCC3)c2)nc(C(C)C)n1 +O=C(NC1CC1)C1CC(=O)N(c2cc(F)cc(F)c2)C1 +CNC(=O)CC(c1cc(Cl)ccc1OC)C1CC1 +CC(CNC(=O)c1ccccc1S(C)(=O)=O)N1CCOCC1 +Cc1cc(C)c(CNC(=O)Cn2c(=O)oc3ccccc32)c(=O)[nH]1 +CNC(=O)c1ccccc1NC(=O)c1ccc(N)cc1 +OC(c1ccc2c(c1)OCCCO2)C1CCCOC1 +CCCCOc1cccn2c(-c3ccc(N)cc3)nnc12 +COCCC(C)NC(=O)Nc1ccc(-n2nc(C)cc2C)nc1 +CC1CCCC(N(C)C(=O)Cn2nc(-c3ccccc3)ccc2=O)C1 +CC(CNS(=O)(=O)C(C)C)c1ccc(F)cc1 +Cn1cc(NC(=O)NCCc2cccc(F)c2)cn1 +CCc1nnc(SCC(=O)Nc2sc3c(c2C#N)CCC3)n1N +O=C(Nc1ccccn1)c1cc2c(=O)c3ccccc3oc2o1 +C#Cc1cccc(NCC(=O)N(CCC#N)c2ccccc2F)c1 +CC1(C)CCC(CNC(=O)C2CCCN2C(=O)C2CC2)CC1 +CC1CCCN(C(=O)c2ccc(C(=O)N3CCCC(C)C3)cc2)C1 +O=C(Nc1nnc(-c2cccs2)s1)N1CCC(O)CC1 +Cn1c(C2CC2)nc2cc(C3CCC(=O)C3)ccc21 +COC(=O)c1cccc(NC(=O)c2cc(C(N)=O)cn2C)c1 +C(Sc1nnc(NC2CC2)s1)c1noc(C2CC2)n1 +CCC(CO)Nc1cc2nc(C)sc2cc1N +Cc1n[nH]c(C)c1CCNC(=O)c1ccc2ccn(C)c2c1 +Cc1cc(C(=O)Nc2ccc(C(N)=O)nc2)c(C)cc1Br +Cc1ccc(S(=O)C2CCCC3(O)CCCN=C23)cc1 +CCn1c(=O)oc(=O)c2cc(Br)cc(F)c21 +CC(C)(CO)NC(=O)c1cn(-c2ccccc2)nn1 +C#CCN1CCN(C(C)C(=O)N(C)C(C)C)CC1 +O=C(CNc1cc(Cl)cc(Cl)c1)N1CCCC1 +CCc1nc(CC(=O)Oc2ccc(C#N)cc2)cs1 +COC1CCC2C1OCCN2C(=O)c1cn(C)c2ccccc12 +COCCOC(=O)c1sc(-c2c(C)c(C)nn(C)c2=O)nc1C +CC(=O)Nc1cccc(NCc2ccc(F)c(C)c2)c1 +COCCOc1cccc(NC(=O)NCc2ccncc2)c1 +CC(C)CCOc1ccc(C(=O)Nc2nccn(C)c2=O)cc1 +O=C(OCc1ccccc1)N1CCCCC1CCCO +COC(=O)C1(NCc2nnc(Cc3ccccc3C)o2)CCCC1 +CC1CCC(NC(=O)c2scnc2C2CC2)C(C)C1 +COc1ccc(-c2noc(C(C)NC(=O)C3CC3)n2)cc1 +CN1CCc2ccc(C(=O)N3CCc4cnccc43)cc21 +COc1cccc(NC(=O)C2CC(=O)N(C)C2c2ccccc2)c1 +Cc1ccc(NC(=O)c2cnc(CC(C)C)nc2N)nc1 +Cn1ccnc1SCC(=O)Nc1ccc(Cl)cc1N +Cc1noc(C2CCN(C(=O)CC3CC4CCC3C4)CC2)n1 +CCOC(=O)c1ncoc1-c1ccccc1C(=O)NC1CC1 +Cc1cc(C(=O)N(Cc2ccccn2)C2CC2)cc(C)c1OC(F)F +COc1ccc2c(c1)C(Cc1ccccc1)NC(=O)CC2 +Cc1cc(C)c(C(=O)NC2COC3(CCCC3)C2)c(=O)[nH]1 +CC(NC(=O)c1ccc2ncsc2c1)c1ccccn1 +COc1ccc(F)cc1C(C#N)CC(=O)NC1CC1 +COc1ccc(OC2CCN(C(=O)C(C)n3cccn3)CC2)cc1 +Cc1nc(CN2CCCC3(C2)CN(c2ncccn2)CCO3)cs1 +Cc1ccc2cccc(NC(=O)c3ccc(N4CCCC4=O)cc3)c2n1 +NC(=O)NCC1CCCCN1C(=O)Cc1ccccc1Cl +O=c1cc(CSc2ccc3c(c2)OCCCO3)nc2sccn12 +N#CCCN(Cc1ccco1)C(=O)c1cccc(-n2cccn2)n1 +COC(=O)COc1cc(C)cc2oc(=O)c3c(c12)CCC3 +CCCCc1ccc(-n2nnnc2SCCC#N)cc1 +CC1CCCC(CNC(=O)N2CCN(Cc3ccncc3)CC2)C1 +COc1ccc(CC(=O)Nc2cccc(NC(C)=O)c2)cc1 +CCCn1nc(-c2ccc3c(c2)OCCO3)cc(CO)c1=O +CCC(=O)N1CCC(NC(=O)Nc2ncco2)C1 +COc1cc2ccccc2cc1C(=O)NCCCN1CCOCC1 +CC(C)c1ncc(Cl)c(C(=O)NCc2cnn(C)c2)n1 +COc1cc(CNC(=O)NCc2ccc(-c3ccn[nH]3)cc2)ccn1 +CCN(CC)C(=O)c1cc2ccc3cccnc3c2[nH]1 +O=C(NCCC(O)c1ccc2c(c1)OCO2)c1ccc2c(c1)OCO2 +CC(CC(=O)N1CCN(C2CCCCC2O)CC1)c1ccccc1 +Cc1cc(F)ccc1CCNC(=O)NCc1nc(-c2ccco2)n[nH]1 +CCn1c(C2CCCN(C(=O)c3cnn4cc[nH]c34)C2)n[nH]c1=O +CC(C)NC(=O)C1CCCC(NC(=O)N(C)Cc2nccs2)C1 +N#Cc1ccc(CSc2nncc3ccccc23)cc1 +O=C(NCc1ccccc1)c1ccc(OCC2CCCO2)cc1 +O=C(NCC1COc2ccccc2C1)c1ccc(=O)[nH]c1 +O=C(N=c1[nH]ccn1Cc1ccccc1)c1cnccn1 +CC(C)(C)OC(=O)N1CCC(S(=O)(=O)c2ccccn2)C1 +COc1ccc(S(=O)(=O)CC(=O)Nc2cc(C)on2)cc1 +CCc1cccc(NC(=O)Cc2cn3ccccc3n2)c1 +O=C(COc1cccn(CCO)c1=O)N1CCCC1 +Cn1nc(CO)cc1-c1cccc(Br)c1 +Cc1ccc(C)c(C(=O)NC(C)c2nnc3ccccn23)c1 +CNC(=O)C1CN(C(C)C)CCN1C(=O)c1cncs1 +Clc1ccccc1-c1nnc2sc(-c3cnccn3)nn12 +O=C(Cc1ccccc1)NCc1cc(Cl)c2c(c1)OCCCO2 +COC(=O)c1ccc(F)cc1NC(=O)CCc1nc(C(C)(C)C)no1 +Cc1ccc2nc(C)c(C(=O)OCC3CCC(=O)N3)cc2c1 +Cc1cc(C)c(NC(=O)c2ccc(C)nc2N)c(Cl)c1 +CCC(CC)c1nnc(NC(=O)c2ccccc2-n2cccn2)s1 +O=C(NCc1ccc(-n2ccnc2)cc1)c1cccnc1-n1cncn1 +O=C(NCc1ccc(Cl)cc1)C1CSc2nccc(=O)n2C1 +COc1ccc(C(=O)NCCNC(=O)C2CC2)cc1Br +O=C(COc1ccc(F)cc1)N1CCC2(CC1)OCc1ccncc12 +CC(NC(=O)N1CCOCC1)c1ccc(-n2ccnc2)cc1 +COc1ccc(NC(C)=O)cc1NS(=O)(=O)c1c(C)noc1C +COc1nc(C2CCCCC2)nc(NCc2ccco2)c1N +O=C(c1ccco1)N1CC2CN(c3ncccn3)CC2C1 +CC(=O)N(C)c1ccc(NC(=O)c2ccc(C)c(C)c2)cc1 +Cc1n[nH]c2c(Nc3cccc(CN4CCOCC4)c3)ncnc12 +c1csc(C2NCCc3ccc4[nH]ccc4c32)c1 +Cc1ccc2c(c1)N(CC(=O)NC(CO)c1ccccc1)C(=O)CO2 +CCOC(=O)c1noc(C(=O)N2CCCCC2C)c1N +CN(C)C(=O)c1ccc(C(=O)N(C)CCc2ccccc2)cc1 +CCCCn1nccc1NC(=O)Cc1ccc(C)s1 +Cc1noc(C)c1CN(C)Cc1cc(Cl)cc(Cl)c1 +CN(CC1CC1)S(=O)(=O)NCCc1nc2ccc(F)cc2n1C +CCc1ccc(CN(C(=O)CCc2ccncc2)C2CC2)cc1 +CCOC(=O)CC1NCCc2ccc(Cl)cc21 +Oc1cccc(CC2NCCc3c(F)cc(O)cc32)c1 +CCN(CCn1cccn1)c1nc2nonc2nc1N(C)C +CCn1ccnc1SCCCN1CCOC1=O +CCCCCCC(C)NC(=O)c1nc2nc(C)cc(C)n2n1 +CCNS(=O)(=O)c1ccc(C(=O)NCc2cccc(C#N)c2)cc1 +O=C1CC2(CCN(c3ncccn3)C2)CN1c1cccc(F)c1 +Cc1ccc(CNC(=O)c2nc(N3CCOCC3)ncc2Cl)cc1 +Cc1n[nH]c(SCC(=O)Nc2ccc(Oc3ccccc3)cc2)n1 +Cc1n[nH]c(C(=O)NC(C)COCC(F)(F)F)c1Br +CC(C)OC(=O)CC(NC(=O)c1ccco1)c1ccccc1Cl +CC(NC(=O)CCCc1cccc(N)c1)c1ccccc1 +CCOc1ccccc1NC(=O)NCCn1ccc(C(F)(F)F)n1 +CC(=O)Nc1cccc(NCCC(=O)c2cccs2)c1 +CN(C(=O)CCc1ccccc1)C(C#N)c1cccnc1 +O=C(NCCO)c1cccc(Oc2ccccc2)c1 +CCOC(=O)c1cc(OC(C)=O)c2cccc(F)c2c1 +COc1cccnc1-c1cc(NCc2ccccn2)nc2[nH]ccc12 +Cc1cnc(CNC(=O)CCCc2cn[nH]c2)cn1 +CC1=Nc2ncnn2C(c2ccc(Cl)cc2)C1C(N)=O +CCS(=O)(=O)NCCN1CCN(C(=O)c2cccs2)CC1 +Cc1nn2ccccc2c1C(=O)NCCC(=O)Nc1ccccc1 +Cc1ccc(C(=O)C(C)Sc2nnc(-c3cccnc3)n2C)cc1 +CN(Cc1cnn(C)c1)C(=O)COc1ccc(-c2ccccc2)cc1 +CCOc1ccc(CNC(=O)N2CC(C)c3ccccc32)cc1OC +CCc1nnc(NC(=O)COc2ccc3c(C)cc(=O)oc3c2)s1 +Cc1cccc(NCc2noc(C(C)C)n2)c1C(=O)N1CCCC1 +O=C(CCc1cccs1)N1CCN(c2ccc(F)cc2)CC1 +COc1ccc(C2CCCN2C(=O)C2CCN(C)C(=O)C2)cc1 +COc1ccccc1CN1CC(C(=O)NC(C)(C)C)CC1=O +CC(C)(C)OC(=O)NCC1NCCc2c(O)ccc(F)c21 +Cc1ccc(CNC(=O)C2CC(=O)N(CC(F)(F)F)C2)s1 +CCC(C)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 +O=C(Nc1nnc2ccccn12)c1cccc(OCc2cccnc2)c1 +Cc1nc(NC(=O)c2ccc(CC#N)cc2)sc1C +COc1cccc(NC(=O)c2cn(-c3ccccc3)cn2)c1 +COc1ccc2c(c1)OCC(C(=O)Nc1nc3ccc(F)cn3n1)C2 +CCOC(=O)Nc1c(-c2ccccc2)nc2ncccn12 +CCCc1cc(C(=O)NC(C)Cc2ncccc2C)n(C)n1 +CCCNC(=O)C1CCCN(C(=O)NCc2ccc(F)cc2)C1 +CC(NC(=O)CCCc1nc(C(C)(C)C)no1)c1cccs1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)NCc2ccc(C)cc2C)c1 +COc1ccccc1CN(CC1CCCO1)C(=O)c1scnc1C +Cn1c(C(C#N)C(=O)CCn2ccccc2=O)nc2ccccc21 +CN(Cc1ccco1)C(=O)Cc1csc(N2CCCC2=O)n1 +CCOCc1ccc(CNC(=O)CN2CC(C)OC(C)C2)cc1 +CC(C(=O)NC1CC1)n1ccc(-c2ccc(F)cc2)c1 +COc1ccccc1N1CCN(C(=O)c2cc(C3CC3)n[nH]2)C(C)C1 +Cc1ccc(C)c(SCC(=O)NCc2ccco2)c1 +COc1cccc(-c2ccc(=O)n(CC(=O)NC3CCCCC3)n2)c1 +CC(C)(C)C(=O)CN1CCN(c2ccccc2O)CC1 +Cc1cc(C(=O)N2CCN(C(=O)c3ccc(O)cc3)CC2)[nH]n1 +COCCCC(=O)Oc1ccc(Cl)cc1Cl +CC1=CCC2CN(C(=O)Cc3ccc(N4CCNC4=O)cc3)CC2C1 +Cc1cnn(Cc2ccccc2Br)c1N +CC(C)(C)c1cnc(CNC(C(=O)N2CCCC2)c2ccccc2)o1 +OCCCCC(O)c1cc(Br)cs1 +CCOC(=O)CCC1NCCc2ccc(Cl)c(OC)c21 +CN(C)C(=O)CSc1nnc(-c2ccccn2)o1 +CC1CCCC(C)N1C(=O)c1cc(Br)ccc1F +CC(=O)Nc1cc(F)c(F)cc1NC(=O)c1nc2nccc(C)n2n1 +CCc1nc(Cc2nc(CC(=O)NC3CCCC3)no2)cs1 +Cc1cc(C(=O)OCc2ccc(C#N)cc2F)c2c(C)noc2n1 +COc1ccccc1C(CNC(=O)c1ccc(C#N)cc1)OC +Cc1nc(CNC(=O)CCc2ccc(-c3ccccc3)o2)c(C)s1 +Cc1nn(C)cc1C1CC(C(=O)NC(C)(C)C)N(C)S(=O)(=O)N1 +Cc1cc(C)c(NC(=O)CSc2nncn2C(C)C)c(C)c1 +Cc1cc(-n2cc(C(=O)N3CCC(C)CC3)nn2)ccc1F +CC(Sc1nnc2ccccn12)c1nc2ccccc2c(=O)[nH]1 +Cc1cccc(C(C)C)c1NC(=O)COc1ccc(C(N)=O)cc1 +CNS(=O)(=O)Cc1c(Cl)cccc1Cl +CN(C)C(=O)c1cc(OC2CC2)c(OC(C)(C)C)cn1 +Cc1ccn(CC(=O)Nc2cnn(CCc3ccccc3)c2)n1 +O=C(NCCc1ccc(F)cc1)C1CC1c1ccco1 +Cc1nc(-c2ccc(Oc3ncccc3C#N)cc2)no1 +Cc1nnsc1C(=O)NCC(O)c1ccc2c(c1)CCO2 +COCCNC(=O)NCCNC(=O)c1ccc(C)c(F)c1 +Cc1nn(C)c2sc(C(=O)N(C(C)C)C3CCC3)cc12 +CCC(=O)Nc1ccc(S(=O)(=O)Oc2ccccc2)cc1 +c1csc(N2CCN(c3cc(C4CC4)nc4ncnn34)CC2)n1 +Cc1nnsc1-c1nn2c(-c3ccncc3)nnc2s1 +O=C(Nc1cccc(Cn2cccn2)c1)c1ccc(-c2cnco2)cc1 +CCCCNC(=O)c1ccc(-n2nc(C)cc2C)cc1 +CCN(Cc1cnn(C)c1)C(=O)CNC(=O)C1CC1 +COc1ccc(-c2nccn2CC(N)=O)cc1OC +CCCn1c(SCC(=O)Nc2ccc(F)cc2)n[nH]c1=O +COc1cccc(C(=O)N(C)CCOc2ccc(Cl)cc2)c1F +O=C(CC1CSc2nccc(=O)n21)NCc1ccc(Cl)cc1 +O=C(NCc1ccccc1F)Nc1ccn(CCN2CCOCC2)n1 +CC(C)(C)OC(=O)N1CCCC(C(=O)NCC(F)(F)F)C1 +Cc1nc(C(=O)NC2CCOC(C)(C)C2)c(-c2ccccc2)s1 +O=C(NCC1CC1)c1cncc(Br)c1 +Nc1cccc(Cn2ccnc2Cc2ccccn2)c1 +Cc1csc(CCCNC(=O)c2c[nH]nc2-c2ccccc2)n1 +Cc1cnc(N2CC3CCC2C3OCC2CC2)nc1 +Cn1nnnc1-c1cccc(NC(=O)C2CC(=O)Nc3ccccc32)c1 +Cc1nn(-c2ccccc2)c2sc(C(=O)NCc3ccccn3)cc12 +Cc1noc(CSc2nnnn2Cc2ccco2)n1 +COc1ccc(C2OC(=O)C(C)(C)C(=O)C2(C)C)cc1OC +CN(Cc1cnn(Cc2ccccc2)c1)C(=O)c1cc2ccccc2[nH]1 +Nc1c(NCC2CCCO2)ncnc1Nc1ccccc1Cl +CC(=O)Nc1cccc(NC(=O)c2cccc(C#N)c2)c1 +Cc1ccc(C(=O)NC(Cc2ccccc2)C(=O)NC2CC2)c(C)c1 +O=c1ccc2ccc(OS(=O)(=O)c3ccc(F)cc3)cc2o1 +CCOC(=O)c1ccc(NCc2ccsc2)c(N)c1 +Cc1nc2sc3c(c2c2nc(C(=O)NCC(C)O)nn12)CCCC3 +O=C(c1ccc2[nH]ccc2c1)N1CCC(Oc2cnccn2)CC1 +CC(=O)Nc1ccc(NCC(=O)N(C)C2CCCCC2)cc1 +CCCCN(C)C(=O)c1onc(-c2ccccc2OC)c1N +NC(=O)C1(NC(=O)CCCC(=O)c2ccc(F)cc2)CCCCC1 +O=C(C1CCN(c2ccc(F)cc2)C1=O)N1CCCCC1 +CCC1CN(C(=O)c2nccnc2N)CC1N1CCOCC1 +CCCNC(=O)NCc1cccc(CN2CCOCC2)c1 +CCOC(=O)c1cc(NC(C)C(=O)NC)ccc1N +CCCc1nnc2n1NCC=C(c1ccccc1)S2 +Cc1ccc(C)c(CN(c2ccc(C#N)cc2)S(C)(=O)=O)c1 +Oc1ccc2c(c1)CCNC2c1cc(F)ccc1F +CC(C)(C)OC(=O)CSc1nc2ccccc2[nH]1 +CN(Cc1cscn1)S(=O)(=O)c1cc(N)ccc1Cl +CCc1cccc(C)c1NC(=O)CC(NC(C)=O)c1ccccc1 +CC(C)(C)c1csc(CNC(=O)Cn2nnc3ccccc32)n1 +CNC(=O)c1cccc(OC(=O)Cn2ncc(=O)c3ccccc32)c1 +CC(Oc1ccc(Br)cc1)C(=O)NCC(=O)NC1CC1 +CC(NC(=O)c1nn(-c2ccccc2)c(=O)c2ccccc12)C1CC1 +Cc1nn2cc(C(=O)NCC(=O)Nc3ccc(F)cc3)nc2s1 +CN(C)c1ccc(C(=O)N(C)C2(C#N)CCC2)cc1F +O=C(NCCOc1ccccc1)c1cnc(-c2ccccc2)nc1 +Cc1c(Cl)cccc1NC(=O)Cn1c(C)nc2ccccc21 +CN(C)c1ccc(S(=O)(=O)N2CCCC2)cn1 +Cc1cc(OCC(=O)Nc2ccccc2C(N)=O)ccc1Cl +COc1ccnc(NC(=O)CCN(Cc2ccccc2)C(C)=O)c1 +CCOc1ccc(C(C)NC(=O)c2cc(CC)[nH]c(=O)c2)cc1F +Cn1ccnc(NC(=O)c2ccc3c(c2)CCCC3)c1=O +c1ccc2c(c1)nc(C1CC1)n1nc(-n3cnnn3)nc21 +CCCC1CN(C(=O)Cc2cccc(C(=O)OC)c2)CCO1 +CCn1nc(C)c(S(=O)(=O)NCCCOC)c1C +Cn1cc(Cc2nc(CC(=O)NC3CCCC3)no2)c2ccccc21 +O=C(Nc1ccc(NC(=O)C2CCCO2)cc1)c1ccc[nH]c1=O +CCC(CNCc1cn(C)nc1-c1ccncc1)c1ccccc1 +COc1c(Br)cccc1CCNC(=O)CC(F)(F)F +Cc1[nH]ncc1CCCNC(=O)N1CCOC(C)C1 +CCC(C)n1c(C)c(C)n2c3c(=O)n(CCCO)c(=O)n(C)c3nc12 +O=C(NCc1ccco1)C1CCN(C(=O)c2cccc(F)c2)CC1 +C=CCNc1ncnc2c1CCN(C(=O)COc1ccccc1)CC2 +CC(C)c1ccccc1NC(=O)C(O)c1ccc(F)cc1 +O=C(c1ccc(Oc2ccccc2)cc1)N1CCCS1(=O)=O +Cc1c(Cl)cccc1-n1nnc(CO)c1-c1ccncc1 +COc1ccc(-c2c(N)nc(=O)[nH]c2C)cc1C(C)C +COC(=O)N1CCN(C(=O)CCn2c(C)cccc2=O)CC1 +Cc1ccc(OCCNc2cc(C)nc3ncnn23)cc1 +NC(=O)Cc1ccc(NC(=O)c2ccc(F)cc2F)cc1 +Cc1cc(C(=O)N2CCCC2c2cnn(C)c2)c(C)n1C(C)C +CC(=O)N1CCN(C(=O)C2CC(=O)N(c3ccc(C)cc3)C2)CC1 +O=C(CCCc1cccs1)Nc1nc(-c2ccco2)n[nH]1 +Cc1cccc(C(=O)NC(C)C(N)=O)c1NC(=O)c1ccccc1F +Cn1nc(C(=O)Nc2c[nH]cc(Br)c2=O)ccc1=O +CSc1ccc(C)c(C(=O)NCCCOC(C)C)c1 +COC(C)(C(=O)Nc1cccc(C(=O)NC2CC2)c1)c1ccccc1 +O=C(NCCc1cccc(O)c1)NC1CCN(c2ccccc2)C1=O +Cc1cccc(C)c1NC(=O)c1ccc(Cn2cc(Cl)cn2)o1 +COc1ccc(C(=O)NCCNC(=O)c2ccccc2O)cc1F +Cc1c(-c2nc3c([nH]2)CC(C)(C)CNC3=O)cnn1C +CCc1ccc(NC(=O)C2CN(c3ncnc4c3nnn4C)C2)cc1 +CS(=O)c1ccc(C(=O)N(Cc2ccco2)Cc2ccco2)cc1 +COc1ccc(Cc2nnc(SCc3ccccc3)o2)cc1OC +Cc1cnc(-c2cccc(NC(=O)N(Cc3ccncc3)C3CC3)c2)o1 +CN(CC1CC1)C(=O)c1c[nH]nc1-c1ccccc1F +CC(CCc1ccccc1)NC(=O)Cn1ncn2cccc2c1=O +CCCn1nnc2c(C(=O)N3CCCCC3)ncn2c1=O +COc1ccc(OCCNC(=O)c2ccccc2C)cc1 +CNc1ccc(S(=O)(=O)N2CCc3ccccc32)cn1 +CSc1ccccc1NC(=O)COC(=O)c1cnc(C)cn1 +COc1cc(C(=O)NC(C)(C)CO)ccc1Cl +COc1ccc(NC(=O)NCC#CCOc2cccnc2)cc1OC +Cc1cc(NC(=O)NC(C)c2ccc3c(c2)OCCCO3)n(C)n1 +CC1CCCN(C(=O)CNC(=O)c2ccsc2)C1 +NC(=O)C1(NS(=O)(=O)Cc2ccccc2F)CCCC1 +Cc1ccsc1C(=O)OC1CCN(CC(F)F)CC1 +COc1ccccc1OCC(=O)Nc1cccnc1 +Cc1nccc(C(=O)NCCN2CC(C)OC(C)C2)n1 +COC(=O)Cc1ccc(OC(=O)CC2CCCC2)cc1 +C=CCCCN(C)C(=O)C1COc2ccc(F)cc2C1 +CC(C)C(NCc1ccc(S(C)=O)cc1)C(=O)N1CCOCC1 +COc1ccccc1-c1nn(C)cc1C(=O)OCC1CCCO1 +CC(=O)NC(C(=O)Nc1cccc(-c2cn[nH]c2)c1)C(C)C +COCCSc1nnc(-c2ccccc2O)n1N +CC(=O)N(CCc1ccccc1)CC(=O)Nc1cccc(C(N)=O)n1 +CC(C)NC(=O)Nc1ccc(C(=O)N(C)CCC(F)(F)F)cc1 +N#Cc1cccnc1N1CCCN(C(=O)COC2CCCC2)CC1 +N#Cc1c(F)cccc1NCCNS(=O)(=O)N1CCOCC1 +O=c1[nH]c2ccsc2c(=O)n1Cc1ccccc1Cl +N#Cc1ccnc(N2CC(CO)C(CN3CCOCC3)C2)c1 +Cc1nnc(NC(=O)c2cc3c(s2)CCCC3)o1 +Cc1ccc(Cl)c2c1CCNC2c1ccnnc1 +NC(=O)c1cccc(S(=O)(=O)N2CCC(Oc3cccnc3)C2)c1 +COC(=O)N1CCN(C(=O)c2ccc(N)cc2)CC1 +O=S(=O)(CCN1CCN(c2ccccc2)CC1)c1ccccc1 +O=C(Nc1cccnc1)C1(c2ccccc2)CCOCC1 +CCn1c(NCCO)nc2c1c(=O)n(C)c(=O)n2CC +O=C(CSc1nnnn1C1CC1)c1cc2ccccc2o1 +O=c1c2ccsc2ncn1Cc1ncc(-c2cccs2)o1 +CN(CC(O)COc1cc(Cl)cc(Cl)c1)S(=O)(=O)O +CC(=O)N1CCC2(CC1)OCCN2S(=O)(=O)c1ccc(C)cc1 +NC(=O)c1ccnc(-c2ccccc2CN2CCOCC2)c1 +CC(C)(C)NC(=O)CNc1nc(C(F)(F)F)nc2ccccc12 +CCC(C)C(=O)N1CCCC(c2nc(-c3ccc(C#N)cn3)no2)C1 +Cc1cc(F)cc(NC(=O)N2CCCC(C)C2CO)c1 +CC(C)NC(=O)C1CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +O=C(Cn1cnc2sccc2c1=O)c1cccs1 +O=C(Nc1cccc(N2CCCC2=O)c1)c1ccno1 +COCCN(C)C(=O)Nc1c(C)cc(Br)cc1OC +Cc1c(NS(=O)(=O)c2ccccc2Cl)cccc1-n1cnnn1 +CC(=O)Nc1nc(C(=O)Nc2cccnc2)cs1 +CC(=O)N1c2ccccc2CC1C(=O)NCc1ccc(Cl)cc1 +O=C(CC1Sc2ccccc2NC1=O)Nc1cc(C2CC2)n[nH]1 +NC(=O)CCn1nc(-c2ccc3c(c2)OCCCO3)ccc1=O +CC(=O)c1ccc(Oc2ccc(F)c(F)c2)c(N)c1 +CC(C)CC(=O)Nc1sc2c(c1C(=O)NC1CC1)CCC2 +CC(C)CCC(C)NC(=O)NCC(O)c1ccccc1F +Cc1ccc(-c2cc(C(=O)N(C)CC(=O)N3CCOCC3)[nH]n2)cc1 +O=C(c1cccc(NCc2ccc(F)cc2F)c1)N1CCOCC1 +Cc1cccc(NC(=O)Nc2cc(C(=O)N(C)C)ccc2Cl)c1 +COC(=O)c1ccc(C(=O)NCc2cnc(C)s2)s1 +COCCNC(=O)C1COC(=O)N1Cc1ccc(SC)cc1 +N#Cc1c[nH]c(C(=O)Nc2ccc3[nH]nnc3c2)c1 +COc1ccc(CCNC(C#N)c2cccs2)cc1 +Cc1cnc(CNC(C)c2c(C)nn(CC(F)(F)F)c2C)o1 +Cc1cc2nc(-c3ccccc3)cc(NCC3CCC(=O)N3C)n2n1 +OCc1cccc(-c2cc(C(F)(F)F)ccn2)c1 +CC(=O)C(C)CSc1nnc(-c2ccco2)n1C +CC(C)C(c1ccccc1)N(C)C(=O)c1cnc(C2CCCO2)s1 +Cn1nccc1CNC(=O)NCC1CC12CCCc1ccccc12 +COc1ccccc1-c1nc(C(=O)Nc2nccn(C)c2=O)cs1 +CC(=O)c1ccc(N2CCCOC(C)C2)c(F)c1 +CC(C)Cc1ccc(C(O)CNCc2cccnc2)cc1 +CN1CCN(C(=O)c2cc3c([nH]c2=O)CC(C)(C)CC3=O)CC1 +Cc1ccc(-c2cc(C(=O)NCc3nc(-c4ccncc4)n[nH]3)[nH]n2)o1 +CS(=O)(=O)N1CCc2c(CNC(=O)c3ccco3)cncc2C1 +CSc1ccc(OCC(=O)N(C)Cc2ccccc2F)cc1 +Cc1nnnn1CC(=O)NCCCOc1ccccc1F +O=C(c1ccccc1F)N(CCc1cccc(F)c1)C1CC1 +CN(Cc1ccc(F)cc1)C(=O)c1cccc(Cl)c1 +Cc1ccc(C)c(N2CC(C(=O)NC3CCCC3)CC2=O)c1 +COc1ccc(S(=O)(=O)N(C)Cc2ccc(C)cc2)cc1 +CCCNS(=O)(=O)c1ccc(NC(=O)CCC)cc1 +CCn1c(=O)c2ccccc2n(Cc2nc(-c3ccccc3)no2)c1=O +N#Cc1cccc(CN2C(=O)C(=O)c3c(Br)cccc32)c1 +CNS(=O)(=O)c1cc(NC(=O)c2ccccn2)ccc1C +CSc1ccc(NCc2cnn(-c3ccccc3)c2)cc1 +c1cc(NCc2ccncc2)cc(-n2cccn2)c1 +COCc1nnc(NC(=O)c2sc(-c3ccccc3)nc2C)s1 +CCC(CC)C(=O)Nc1cc(NC(C)=O)ccc1OC +COc1ccc(-c2nc(C)c(C)o2)cc1Br +Cc1ccc(C(=O)Oc2cccc(C(N)=O)c2)s1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1ncccc1C +CN(C)C(=O)CCNC(=O)Nc1cccc(-c2nnc3n2CCC3)c1 +Cc1cc(=O)c2c(C)nc(-c3ccccc3)nc2[nH]1 +c1cc(-c2cc[nH]n2)cc(-c2cnc3ccccc3n2)c1 +COCC(=O)NCc1nnc(SC)n1-c1ccc(OC)cc1 +CNC(=O)CCC(C)(C)NC(=O)c1cccc2c(=O)cc(C)[nH]c12 +O=C(Nc1cnn(CC(F)(F)F)c1)c1cc(Cl)ccc1Cl +CCCN(C(=O)Cn1nc(C)ccc1=O)c1cccc2ccccc12 +Cc1cnn(C2CN(c3ncnc4ccsc34)C2)c1 +CCC(CC)NC(=O)N1CCN(C(=O)C2CCCO2)CC1 +Cc1ccc(OC(=O)c2ccc3c(c2)[nH]c(=O)n3C)cn1 +Cc1ccc(F)cc1C(=O)N1CCc2cc(F)ccc2C1 +Cc1cccc(CN(C(=O)CCSc2ccccn2)C2CC2)c1 +COc1ncc(CN2CCC(c3nc(C)cc(C)n3)C2)cn1 +CC(=O)c1cnc(NCC(O)COC2CCCCC2)nc1C +O=C(CC1CCc2ccccc21)N1CCc2ncccc2C1 +N#Cc1ccc(NCC(=O)N2CCN(CC3CCCO3)CC2)cc1 +CNC(=O)C1(C)CN(Cc2ccc3[nH]ccc3c2)CCO1 +CCC(C)(C)NS(=O)(=O)c1sccc1Br +Cc1noc(C)c1CCC(=O)OCC1CC=CCC1 +N#CCc1c(-c2ccc3c(c2)OCCO3)nc2sccn12 +Cc1cc(F)ccc1S(=O)(=O)N1CCC(Oc2ccccc2)CC1 +CNc1snc(C)c1C(=O)N(C)CCOCC1CC1 +Nc1nccnc1C(=O)Nc1nc2ccc(F)cc2s1 +Cc1cccc(-n2nnc(-c3ccc(F)c(F)c3)c2N)c1 +CCCc1nc2sc3c(NCCCO)ncnc3c2c2c1CCC2 +Cc1ccc(-n2nnnc2SCC(=O)NCC(F)(F)F)c(C)c1 +Cc1nc(NC(=O)C2CC(=O)N(CC3CC3)C2)sc1C +Cc1noc(C)c1S(=O)(=O)N(C)C1CCCCC1 +COCCNC(=O)c1nc(Nc2ccc(F)cc2)c2ccccc2n1 +Cc1nc2c(c(=O)n1C)CCN(C(=O)CCc1ccccc1O)CC2 +CC1(C)CN(CC(=O)NCc2ccco2)c2cc(N)ccc2O1 +Cc1cc(Sc2ccccc2Cl)n2ncnc2n1 +COCc1ccccc1CNC(=O)C1CCCCN1S(C)(=O)=O +COc1cc(S(N)(=O)=O)c(OC)cc1Br +Cc1nc(C(=O)Nc2cccc(S(N)(=O)=O)c2C)cs1 +COCC(=O)NC1CCN(C(=O)C(C)(C)C)CC1 +COc1cccc(OC)c1COC(=O)c1cccc(C#N)c1 +CC(C)(C)n1cc(NC(=O)CNS(C)(=O)=O)cn1 +CC(C)(C)c1ccc(NC(=O)N2CCN(CCO)CC2)cc1 +Cc1noc(C)c1COc1ccc(CN2CCOC(C(N)=O)C2)cc1 +CCOc1cc(C#N)ccc1OCC(=O)N(c1ccccc1)C(C)C +CCc1ccccc1C(=O)NCC(=O)N1CCOCC1 +O=C1CC(NS(=O)(=O)c2cccc(F)c2)CN1 +CC(C)(NC(=O)CCc1nc(-c2ccco2)no1)c1cccc(F)c1 +Cc1nn(-c2ccc(C(C)(C)C)cc2)c(C)c1CO +O=C(NCC1CCCO1)C1CN(c2nc3c(F)cccc3s2)C1 +O=C(C1CCCO1)N1CCc2c(COCC3CC3)cncc2C1 +COc1ccc(-c2nc(CCS(=O)(=O)c3ccccc3)no2)cn1 +Cc1nc2cc(C3CCCCN3C(=O)C3CCCO3)nn2c(O)c1F +Cc1c(-c2noc(C(=O)NCc3ccccc3)n2)oc2ccccc12 +COC1CCCC1OC(=O)Cc1csc(-c2cnccn2)n1 +CC(C#N)Cn1cc(Br)cc(Br)c1=O +CC(=O)NC(C)C1NCCc2c1ccc(F)c2Cl +CCN(Cc1ccccc1)C(=O)CNC(=O)C1CCCCC1 +CC(C)(C)CC(C)(C)NC(=O)c1ccc(C(N)=O)nc1 +N#Cc1cccc(NC(=O)CCn2cc(Br)ccc2=O)c1 +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)Nc1cccc(O)c1 +Cc1ccc(NC(=O)c2csc(-c3cccnc3)n2)cc1 +CC(C)(C)OC(=O)Oc1ccc(-n2cccn2)cc1 +CCc1oc(C(=O)Nc2cccc(-c3cn[nH]c3)c2)cc1C +O=C(Nc1cccc(C#Cc2ccccc2)c1)C1CC(=O)N(C2CC2)C1 +O=C(CCn1cnc2ccccc21)Nc1ccccc1F +O=C(NCc1c(F)cccc1OC(F)F)c1ccc2nncn2c1 +COc1cccc(C(=O)NCC(F)(F)F)c1OC +C=CCCCN(C)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +Cc1cc(-c2cccc(CN3CCOCC3)c2)nc(N)n1 +CC(C)c1nnc2sc(-c3c(F)cccc3F)nn12 +O=C(NC1CCN(C(=O)Cc2cccs2)CC1O)c1cnccn1 +CCc1cc2c(=O)n(CC(=O)Nc3cccc(Cl)c3)cnc2s1 +Cc1cccc(NCCc2n[nH]c(C(C)(C)C)n2)c1 +Cc1nn(C)c2ncc(NC(=O)CNC(=O)c3ccccc3)cc12 +COc1ccc(C(CC(=O)Nc2ccc(C)cc2O)NC(C)=O)cc1 +CCc1cc2ccccc2nc1SCC(=O)N1CCCC1 +COC(=O)c1cc(F)c(C)c(NCc2nnc(C(C)(C)C)o2)c1 +CCc1ccccc1-n1nc(N2CCOCC2)cc1N +CC(=O)c1ccc(Cl)c(NC(=O)c2scnc2C2CC2)c1 +Cc1cccc(NC(=O)Nc2cccc(Cl)c2C)n1 +COC(=O)C1CC(O)CCN1Cc1cnn(C(C)C)c1 +O=C(NCC(O)c1cccc2ccccc12)c1ccccc1 +O=C(NC1CCN(C(=O)c2cc3n(n2)CCCO3)C1)c1ccccc1 +Cc1ccc(S(=O)(=O)N2CCC(Oc3ccccn3)CC2)c(C)c1 +COc1ccc(C2CCCNC2=O)cc1Br +Cc1nnc2ccc(C(=O)N3CCCC3C3CCCC3)cn12 +COC(C)C(=O)Nc1ccnc(Oc2ccccc2)c1 +CCCNC(=O)C(C)NC(=O)Nc1ccccc1OC +COc1cc(C(C)=O)ccc1OC(=O)CSc1ccccc1C +Cc1cc(Br)cc(C)c1NC(=O)c1n[nH]c(N)n1 +CCn1cc(C(=O)Nc2cccnc2)c(=O)c2cc(OC)ccc21 +COCCNC(=O)N1CCN(c2nc3c(F)cccc3s2)CC1 +CCOc1ccc(NC(=O)c2nc3nc(C)cc(C(F)F)n3n2)cc1 +CC(NC(N)=O)C(=O)Nc1ccc(Br)cc1 +CCCNC(=O)c1c(NC(=O)c2ccc(C)cc2)cnn1C +Cc1nnsc1-c1nnc2sc(Cc3ccc(F)cc3)nn12 +COc1ccc(CN(C)Cc2cc(F)ccc2C#N)cc1 +O=C(Cc1ccccc1)NCCC(=O)Nc1ccc(F)cc1 +Cc1oc(S(N)(=O)=O)cc1C(=O)NCCCOC1CCCC1 +CCc1nc(CNc2ccc(Cl)c(Br)c2)no1 +O=C1NCCN1CCNS(=O)(=O)c1ccc(F)cc1 +Cc1noc(C)c1C(=O)Nc1ccc(-c2cn3ccccc3n2)cc1 +C#Cc1cccc(NC(=O)CNC(=O)C(CC)OC)c1 +Cc1c(C(=O)OCC(=O)NC(C)C)nnn1-c1ccccc1Cl +CCOCC1CCCN(C(=O)c2cccc(OCC(N)=O)c2)C1 +Cc1cc(NCc2scnc2C)ccc1C(=O)NC(C)C +N#Cc1nc(COc2cccc(Cl)c2)oc1NCC1CCCO1 +N#Cc1ccc(NCC2CCN(c3ncnc4ccccc34)C2)nc1 +O=C(CCn1ccc2ccc(F)cc21)NCc1ccccn1 +O=C(Cn1cc(Cl)c(=O)[nH]c1=O)c1ccc2ccccc2c1 +Cc1cc(S(=O)(=O)N(C)C)ccc1OCC(=O)Nc1ccccc1 +N#Cc1cccc(S(=O)(=O)Nc2c(F)cccc2N2CCCC2)c1 +CCS(=O)(=O)N1CCc2nc(NC(=O)CC(C)(C)C)sc2C1 +CCC(C)NC(=O)NCc1ccc(-n2nc(C)cc2C)nc1 +CC1Cc2ccccc2N1C(=O)COc1ccccc1N +COc1cc(NC(=O)N2CCCC2c2nc(C)no2)cc(OC)c1 +COc1cccc(NC(=O)CSc2nnc(NC(C)=O)s2)c1 +CS(=O)(=O)NCCNC(=O)N1CCC2(CCCCC2)CC1 +C#CCOC1C(O)C(CO)OC1n1cnc2c(=O)[nH]c(N)nc21 +C=CCNc1nnc(SC(C)C(=O)N2CCCCC2)s1 +CCOC(=O)C1CCN(C(=O)Cc2ccccc2F)CC1 +OC(c1cccc(Cl)c1)c1ccc2c(c1)COC2 +Cc1cc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)c(C)o1 +COCc1nnc(NC(=O)CN2CNc3ccccc3C2=O)s1 +N#Cc1cccc(S(=O)(=O)Nc2ccc(F)cc2)c1 +COc1ccc2c(ccn2CC(=O)N2CCNC(=O)CC2)c1 +O=C(CCn1cncn1)N1CCN(Cc2ccco2)CC1 +Nc1c(F)cccc1C(=O)NCCc1ccc(F)cc1 +Cc1ccc(CNC2=NS(=O)(=O)c3ccccc3N2)cc1 +CC(=O)c1cccc(-c2cc(OC(C)C)nc(N)n2)c1 +CCOC(=O)c1ccsc1NC(=O)c1cc(C)oc1C +COc1ccc(Br)c2c1C(CC#N)NCC2 +CCN(CC(=O)NC(C)(C)C)C(=O)Cn1ccc2ccccc21 +Cc1cccc2sc(NC(=O)CCn3cnnn3)nc12 +CC(=O)Nc1cccc(NC2CCN(C(=O)OC(C)(C)C)CC2)c1 +O=C(CO)N1CC2CC(C1)CN(C(=O)c1ccco1)C2 +O=C(CC1C=CCC1)N1CCCCC1c1nc[nH]n1 +COc1ccc(CC(=O)Nc2ccc(Cl)cc2C(N)=O)cc1 +Brc1ccn2nc(-c3cccnc3)ncc12 +COc1cc(NC(=O)C2CC3CCC2O3)c(OC)cc1Cl +Cc1sc2nc(SCCC(N)=O)n(C(C)C)c(=O)c2c1C +COC1CCN(C(=O)c2cc(F)c(F)c(F)c2)CC1 +O=C(CN1CCN(Cc2ccc(F)cc2)C1=O)NC1CCCC1 +Cc1cc(C(=O)NC(C)Cn2cncn2)c2cnn(C(C)C)c2n1 +CCOC(=O)c1nnc2ncnn2c1C=CN(C)C +Cc1cccc(S(=O)(=O)C(C)C(=O)NC2CCCC2)c1 +CCOC(=O)CN(C(=O)c1cc(C(C)=O)cn1C)C1CC1 +COC(=O)c1cc(NC(=O)CO)cc(C(=O)OC)c1 +Cc1nc(-c2ccco2)ccc1C(=O)Nc1ccc2c(c1)oc(=O)n2C +COCCn1c2c(ccc1=O)CC(NCc1cccc(F)c1)CC2 +Cc1cc(F)ccc1S(=O)(=O)N(C)c1ccc(F)c(N)c1 +COc1ccccc1C(=O)N(C)c1nnc(-c2cccnc2)s1 +COc1ccc(NC(=O)c2ccc(C)c(O)c2)cc1OC +Cc1noc(C)c1N(C)C(=O)c1cn(-c2cccc(Cl)c2F)nn1 +Cc1n[nH]c(=O)c(C(=O)NC2CCCCCC2)c1C +Cc1ccc(C(=O)OCC(=O)Nc2ccccc2C#N)cc1 +CCC(CC)C(O)CNC(=O)C1CC(=O)N(C)C1c1cccnc1 +O=C(c1ccsc1)N1CCC(OCc2nc(C3CC3)no2)CC1 +CN1C(=O)C(C)(C(=O)NCCN2CCOCC2)Sc2ccccc21 +COc1ccc(CNS(=O)(=O)c2c(F)cccc2F)cc1F +Cc1nc(NC(=O)CCC(C)(C)C)sc1SCC(N)=O +COc1ccc(CCn2c(C(C)O)nc3ccccc32)cc1OC +COc1ccc(C2CC(=O)Oc3ccc4c(C)cc(=O)oc4c32)cc1 +N#CC(CC(=O)NCc1ccncc1)c1ccc(Cl)cc1 +CN(C)S(=O)(=O)NCCn1nc(-c2cccs2)n(C)c1=O +CCc1cc(-c2nccn2-c2ccc(-c3ccn[nH]3)cc2)on1 +COC(=O)COC(=O)Cn1cnc2ccccc2c1=O +Cc1ccc(CN(C)C(=O)C2CCCCN2S(C)(=O)=O)o1 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+COc1cc(-c2nccc(CO)n2)cc(Cl)c1OC +O=C(c1ccccn1)N1CCN(CC(F)(F)F)CC1 +COc1ccc(OC)c(CN(CCO)C(=O)c2ccsc2)c1 +N#CC(NCC(F)(F)F)c1ccc2c(c1)OCCO2 +CCOc1cccc(C(=O)N=c2[nH]nc3cc(C)ccn23)c1 +Cc1cc(O)c(C2(O)C(=O)Nc3cc(Br)ccc32)cc1C +C=CCNC(=O)C(C)Sc1nccn1-c1cccc(C)c1C +CCCc1cc(C(=O)Nc2ccc(C(C)=O)c(Cl)c2)[nH]n1 +O=S(=O)(NCc1ccc2ccccc2c1)c1cccnc1 +COc1ccc(S(=O)(=O)NCc2cnn(C)c2)c(C)c1F +Cc1nn(C)c2nc(N3CCCN(c4ccc(F)cc4)CC3)sc12 +CC(C)Cc1cc(C(=O)N2CCC(O)(c3ccccn3)CC2)n(C)n1 +N#Cc1cc2c(nc1SCc1nc3ccccc3[nH]1)CCCC2=O +CNC(=O)C1CCC(NC(=O)NCc2c(C)cc(C)cc2C)CC1 +CC(=O)Nc1ccc(C(=O)CNc2ccc(C)cc2)cc1 +COCC(=O)NCc1cc(-c2ccc3c(c2)OCCO3)on1 +O=C(CSc1nccnc1-n1cccn1)c1ccc(Cl)cc1 +O=C(Cc1csc(-c2ccccc2)n1)Nc1nccs1 +O=C1C=C(Nc2ccccc2)CN1c1ccccc1 +O=C(Cn1cccn1)NC1(c2ccc3c(c2)OCCO3)CCCC1 +CC1CC(CC(=O)N(C)C(C)CC#N)CC(C)(C)C1 +O=C(c1ccncc1)N1CCOc2ccc(F)cc21 +CC(C(=O)NCCc1ccc(F)cc1)S(=O)(=O)c1nncn1C +Cc1nc(N2CCN(CCO)CC2)c(C#N)c2c1CCCC2 +CN(C)C(=O)c1cc(-c2cccs2)nn1-c1ccccc1 +CC(Cc1ccc(O)cc1)N(C)C(=O)c1ccc(-n2cnnc2)cc1 +COc1cc(NC(=O)c2ccc3snnc3c2)cc(OC)c1OC +COC(=O)c1ccsc1NC(=O)C(C)Sc1ccccc1 +Cc1cccc(Cl)c1NC(=O)N1CCCC1CC(C)O +Cc1ccc(OCCNC(=O)N2CCN(S(C)(=O)=O)CC2)cc1 +CCCc1cc(C(=O)NCc2csc(=O)[nH]2)sc1C +COc1cc(OC)c2c(CCC#N)c(C)n(C)c2c1 +CCOC(=O)CN(C)S(=O)(=O)c1ccccc1OC +COc1ccc(C(=O)NCCNC(=O)Nc2ccccc2Cl)cc1 +Cc1ccc(CN2C(=O)CN(C)C(=O)c3ccccc32)cc1 +CN(C)C(=O)C1CCN(C(=O)c2ccc3ccccc3c2)CC1 +O=C(Nc1cccc(-c2nnco2)c1)c1ccc(OCC(F)F)nc1 +CNC(=O)c1cccc(OS(=O)(=O)N(C)C)c1 +CCS(=O)(=O)NCCCNC(=O)c1cc2cc(Cl)ccc2[nH]1 +COc1cc(NC(=O)NCCc2c[nH]c3ccccc23)cc(OC)c1 +CN(C)c1cccc(-c2ccc3nc(N)nn3c2)c1 +COCc1nc(CC(=O)Nc2cc(Cl)c(O)c(Cl)c2)cs1 +Nc1ccc2nc(CC(=O)Nc3ccc(Cl)cc3)oc2c1 +CC1(COC(=O)c2ccc(N3CCCC3=O)cc2)COC1 +CCCNC(=O)CN(C)c1cc(Br)ccc1CO +CCCOc1ccc(C(=O)NC(C)(C)CO)cc1 +Cn1ccnc1SCCNC(=O)c1ccc2nc(C3CC3)oc2c1 +CNC(=O)c1ccc(F)c(S(=O)(=O)N2CCOCC2)c1 +COCC(=O)N1CCC(c2cc3ncccc3c(=O)[nH]2)C1 +Cc1nc(-c2ccc(OCc3nnc(-c4cccs4)o3)cc2)no1 +CC(=O)NCC1CCCN(C(=O)C2C3CC4CC(C3)CC2C4)C1 +CNc1ncccc1C(=O)NCc1cn2nc(C)sc2n1 +CC(=O)NC(C(=O)OCC1CCC(=O)N1)C1CCCC1 +Cc1cccc(NC(=O)c2onc(S(C)(=O)=O)c2N)c1C +COc1ccc(NC(=O)C2(C#N)CCCC2)cc1OC +O=c1ccc(S(=O)(=O)NCc2ccc(F)cc2)c[nH]1 +C=CCn1c(C)c(C(=O)OCC)c2cc(O)ccc21 +Cc1cc(NC(=O)CCSc2ccccc2F)no1 +CSc1ccc(C(=O)N2CCOCC2C2CC2)o1 +CC(C)(CNC(=O)C1CCCN(C(N)=O)C1)c1cccc(Cl)c1 +Cc1nc(CN(Cc2ccccc2)CC2CCCO2)cs1 +O=C(Nc1ccccc1Cl)c1cncc(Br)c1 +CCCCn1cc(C(=O)NC(C)(C)C)c(=O)c2c(N)cccc21 +O=C(NCC1CC1)C1CN(C(=O)c2cccs2)CC12CCOCC2 +Cc1cc(C(=O)N2CCN(C(=O)NC3CCC(C)CC3)CC2)c(C)o1 +O=C(C1CCCO1)N1CCOC(c2ccc(F)c(Cl)c2)C1 +CCc1ccc(OCC(O)Cn2c(C)cc(=O)n3ncnc23)cc1 +COc1ccc(NC(=O)Nc2ccc(C(C)=O)cc2)cn1 +CC(C)C(C)NC(=O)CSc1ccc(N)cc1Cl +COCc1ccc(CNS(=O)(=O)c2cccc(C(N)=O)c2)cc1 +CC(=O)c1nnc2scc(-c3ccc4c(c3)OCCO4)n12 +O=C(NCCCc1nnc2ccccn12)c1c[nH]c2cccc(F)c12 +CCC(NC(=O)NCc1ccco1)c1cccc(S(N)(=O)=O)c1 +Cc1ccn(-c2ccc(N3CCCC(N4CCCC4=O)C3)nn2)n1 +CN(C)C(=O)N1CCN(C(=O)c2ccnc(-n3cncn3)c2)CC1 +Cc1cc(N)ccc1NC(=O)CCSc1cccs1 +Cn1nnnc1SCC(=O)Nc1cc(-n2ccnc2)ncn1 +C=CC1CCN(C(=O)NCc2cccc3cccnc23)CC1 +CCC(=O)NCc1cc(S(N)(=O)=O)ccc1OC +Cc1cc2c(cc1C)C(c1cccnc1F)NCC2 +CCc1cc(C(=O)Nc2ccc(-c3cn4cccnc4n3)cc2)[nH]n1 +COc1cccc(OC)c1COC(=O)c1ccc(-n2ccnn2)cc1 +COC(=O)c1ccc(NC(C)=O)c(OCC(F)(F)F)c1 +CC(C)(CNC(=O)C1CC1(Cl)Cl)NC(=O)OC(C)(C)C +C=CCN1C(=O)c2ccccc2NC1c1c[nH]nc1-c1cccnc1 +Cc1nn(C)c2sc(C(=O)Nc3cccc4[nH]ccc34)cc12 +COc1ccc(C(=O)NCC2CCCCO2)cc1Br +COCc1ccc(C(=O)Nc2ccc(NC(C)=O)cc2)o1 +CC1CCCCN1c1ncnc(NC2CCCCC2)c1N +CC(C)COc1ccc(CCC(O)c2cccnc2)cc1 +CC(=O)NC(C(=O)Oc1cccc(N2CCCC2=O)c1)C(C)C +COc1ccc(NC(=O)c2ccccc2-n2cnnn2)cc1OC +CC(=O)NCc1ccc(C(=O)NC2CCC(C)CC2)cc1 +COC(=O)c1ccc(S(=O)(=O)N(C)CC(C)c2ccccc2)o1 +N#Cc1cccc(COC(=O)CNC(=O)c2cccc(F)c2)c1 +CCCNC(=O)c1cc(-c2c(C)nn(C)c2C)n[nH]1 +CCOc1cc(C(=O)N(CC)CC)nn1-c1ccccc1 +Cc1nn(Cc2ccccc2Cl)c2[nH]c(C3CCOCC3)nc12 +CC(c1cccs1)N(C)C(=O)NCC1CCC1 +COC(=O)c1cccc2c1CCCN2CC(=O)N(C)CC1CC1 +C#CCn1c(C(O)c2ccccc2)nc2cc(C)c(C)cc21 +O=c1[nH]c(SCc2cc(=O)n3ccccc3n2)nc2[nH]cnc12 +COc1cccc(NC(=O)COc2cccc(C(C)=O)c2)c1 +CN(C)c1cccc(C(=O)N2CCc3ccccc32)c1 +COC(=O)CC(NC(=O)C1CC1)c1ccc2c(c1)OCO2 +CC(NC(=O)Cc1cccc(OCC#N)c1)c1nc(C(C)(C)C)no1 +CS(=O)(=O)c1cc(C(=O)OCC(F)F)c(Cl)cc1Cl +O=C(NCC1CCOCC1)C1CC2C(CCN2Cc2ccoc2)O1 +CC1CN(CC(=O)N2CCC(C(=O)N(C)C(C)C)CC2)C(C)CO1 +N#Cc1c(-c2ccccc2)nc2sc(C3CC3)nn12 +CC1CN(Cc2nc3ncc(Br)cc3[nH]2)CC(C)(C)O1 +CC1Cc2nc(N)nn2CC1c1ccc(C(F)(F)F)cc1 +N#Cc1ccsc1NC(=O)c1ccc(OC(F)F)cc1 +CCC(C)CS(=O)(=O)c1ncccc1Br +NC(=O)CSc1nccn1CCc1ccc(F)cc1 +Cc1ccc2ncc(C(=O)Nc3ccnn3C3CCCCC3)n2c1 +CN(Cc1nccn1C(F)F)C(=O)c1c[nH]c2cccc(F)c12 +COCc1nc(CC(=O)Nc2ccc(F)c(C#N)c2)cs1 +CC(C)NC(=O)NCC1CCN(c2ccc(Br)cc2)C1 +COc1ccccc1CN(CCO)C(=O)c1ccnc(SC)c1 +CCOc1ccccc1NC(=O)NCc1nc2ccccc2s1 +CC(C)c1ccc(S(=O)(=O)c2c[nH]c3ccccc3c2=O)cc1 +CC=CC=CC1NCCc2c1ccc(OC)c2OC +CCS(=O)(=O)c1ccccc1C(=O)NCCc1ccc(C)cc1C +CCCNC(=O)CSc1nnc(-c2ccco2)n1-c1ccccc1 +Cc1noc(CCC(=O)N(C2CCC(C)CC2)C2CC2)n1 +CN1C(=O)C(c2ccccc2)CC12CCN(S(=O)(=O)C1CC1)CC2 +CC1(CNC(=O)Nc2ccc(S(C)(=O)=O)cc2)CCCC1 +COC(=O)N(C)c1ccc(NC(=O)NCc2ccccn2)cc1 +COc1cc(-c2ccnc3c2ccn3C)ccc1O +CC(=O)NCC(=O)Nc1ccccc1C(=O)N1CCCCC1 +COc1ccc(-c2nnc(SCC(=O)N3CCOCC3)n2C)cc1 +COC(=O)c1ccc(NC(=O)c2cn(-c3cccc(C)n3)cn2)cc1 +CCCCNC(=O)Nc1ccc(C(=O)N2CCCCCC2)cc1 +C=CCN1C(=O)C(CC)(CC)Oc2c(OCC)cc(CO)cc21 +CC(C)c1cn(CC(=O)N(C)CC2OCCc3ccccc32)nn1 +CN(C1CCCCC1)S(=O)(=O)c1ccccc1F +CC(O)CNC(=O)C(N)c1ccccc1OC(C)C +CNC(=O)c1cccc(C(=O)NC(C)(COC)c2ccccc2)c1 +Cc1noc(C)c1C(C)NC(=O)c1ccc2c(c1)CCCC2 +C=CCOCc1cncc2c1CCN(C(=O)c1cccn1C)C2 +O=C(Cc1noc2ccccc12)N1CCN(Cc2cccs2)CC1 +CCCn1cc(C(=O)Nc2cccc(C)c2)c(=O)c2ccc(C)nc21 +CC(=O)Nc1nc(CC(=O)Nc2ccc3sc(C)nc3c2)cs1 +CCn1nccc1CNC(=O)c1cc(C)nc2onc(C)c12 +O=C(NCCCOc1ccc(F)cc1)c1ccncc1 +COc1ccc(CCC(=O)Nc2ccc(-n3ccnc3)nc2)cc1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)NC(C)C)O2 +O=C(OCCC#Cc1ccccc1)C1CC(=O)N(Cc2ccccn2)C1 +O=C(NCCCNC(=O)c1ccc2ncnn2c1)c1cccc(F)c1 +COCc1ccc(C(=O)N(CC(F)(F)F)C(C)C(C)C)cc1 +O=C(c1ccc[nH]1)N(Cc1ccc(Cl)cc1)C1CC1 +COCC(O)CN(C)C(=O)c1cc(C)ccc1C +COc1cc(OC)c2c(c1)C(c1ccccc1)NCC2 +Cc1ccc(C(O)C(=O)NCc2cccnc2)c(C)c1 +O=c1[nH]nc2cc(-c3ccccc3)nc(NC3CC3)n12 +Cc1nn(C)cc1CN(C)C(=O)COc1ccc(Cl)cc1Cl +CCCCn1nnc2sc3c(c2c1=O)CCCC3 +O=C1OCCN1CCOC(=O)C1(c2ccc(Cl)cc2)CC1 +CCc1nn(CC(=O)NC2CC2)c(=O)c2cc3sc(C)cc3n12 +CCCC(C(=O)OC)N1CCN(c2ccc(F)cc2)CC1 +Cc1nc(C(C)(C)NC(=O)NCCNC(=O)C(C)(C)C)sc1C +Cc1cnccc1CN(C)C(=O)C1CCCN1S(C)(=O)=O +COC(=O)CC1COCCN1C(=O)OC(C)(C)C +COc1c(C)cc(Cl)cc1-c1cc(=O)[nH]c(N)n1 +CC(C)OCCC(=O)N1CC(c2ccc(F)cc2)CC1C +O=C(NCc1cn(-c2ccccc2)nc1-c1ccccc1)C1CCCO1 +CCCn1ncc2[nH]c(-c3cc(Cn4cncn4)c(C)cc3C)nc21 +CCn1cc(NC(=O)c2cccc(Br)c2)cn1 +O=c1c2ccccc2ncn1CC(O)c1cc(F)ccc1F +O=C(NCc1ncccn1)C1CC2C(CCN2C2CCOC2)O1 +CSc1nnc2n(CC(=O)N(C(C)C)C(C)C)c3ccccc3n12 +O=C(NCc1ccccn1)c1ccnc2ccccc12 +O=C(CSc1nncs1)NC1CCCCCC1 +CCN(CCCNc1ncnc2ccsc12)S(C)(=O)=O +O=C(Nc1ccc2c(c1)COC2)c1cccc(CN2CCCC2=O)c1 +COC(=O)c1ccc(CCC(=O)Nc2nc(C(C)C)n[nH]2)cc1 +Cc1ccc(NC(=O)CCc2nc(C3CC3)no2)cc1S(C)(=O)=O +CC(C)CC1COCCN1Cc1cccc2c1OCCCO2 +COc1cccc(CN(C)C(=O)c2sc(-c3nc[nH]n3)nc2C)c1 +CC(OCC1CC1)C(=O)NC(C)c1csc(C(C)C)n1 +CC(C#N)Cn1c(C(C)(C)C)nc2cc3c(cc21)OCCO3 +O=C(CC1CC1)N1CCCC2(CC(Nc3ncccc3F)CO2)C1 +O=C1CC(c2ccc(F)cc2)Cc2c1cnc1ccnn21 +Cc1ccc(C)c(OCC(O)Cn2nc(C)c(C)c(C#N)c2=O)c1 +COC(=O)C1C(=O)c2c([nH]c(C(=O)OCC3CCCO3)c2C)CC1C +COc1ccc(Cl)cc1C(=O)OCC1CCC(=O)N1 +CN(C)c1ccc(C(=O)Nc2ccc(F)cc2F)cc1 +Cc1cc(=O)n2c(n1)SCC2CC(=O)NCc1ccc(Cl)cc1 +CC(Sc1nccn1C1CC1)C(=O)N(C(C)C)C(C)C +O=C(c1cc(-c2cccnc2)on1)N1CCN(c2ccccc2)CC1 +CCOC(=O)C1CCCN(C(=O)c2cc(OC)cc(OC)c2)C1 +Cn1c(=O)ccn(CC(=O)NCC(=O)N2CCCC2)c1=O +CCCN(C)C(=O)CCSc1ccc2c(c1)OCCCO2 +CN(Cc1ccccc1)c1ncccc1CNC(=O)c1ccccc1F +O=C(Nc1ccc(-n2cncn2)nc1)c1cc2ccccc2oc1=O +Cc1ccc(NS(=O)(=O)c2ccc(C)c(C(=O)NCCO)c2)cc1 +CCc1nnsc1C(=O)Nc1cc(C(C)(C)C)n[nH]1 +CCc1cc(=O)[nH]c(-c2ccc3ncccc3c2)n1 +CCOC(=O)N(C)c1ccc(NCc2ccc(C#N)cc2)cc1 +Cc1ccc(-c2csc3ncc(C(=O)NC(C)(C)C)c(=O)n23)cc1 +Cc1nn(CCOc2ccccc2)c(=O)c(C#N)c1C +Cc1nc(C)c(CCC(=O)NC(C)C(C)(C)c2ccccc2)c(=O)[nH]1 +CCc1cnc(CN(C(C)=O)C2CCN(Cc3cnc(C)s3)C2)o1 +O=C(NCc1ccccc1)C1CC1c1ccccc1 +COc1ccc(-c2nnc(NC(=O)C(C)C)o2)cc1 +COc1ccc(O)c2c1C(C(C)NC(C)=O)NCC2 +CCCN1C(=O)C2CCC1CN(C(=O)c1ccc(C)c(O)c1)C2 +O=C(Cc1cn2ccsc2n1)N1CC=C(c2ccccc2)CC1 +N#CCc1ccc(NC(=O)CCCc2nc3ccccc3c(=O)[nH]2)cc1 +NC(=O)CSc1nnc(CCn2ccc(=O)[nH]c2=O)o1 +CCOc1cc(C(=O)N2CCCCCC2)ccc1OCC(=O)OC +CN(CC(=O)OCc1ccc(C#N)cc1)S(C)(=O)=O +Cc1cnc(NC(=O)Cc2ccccc2Cl)s1 +CC(Sc1nc2ncccn2n1)c1cccc(Cl)c1 +CNC(=O)NCC(=O)Nc1cc(F)ccc1NC(C)C +NC(=O)C1CCN(C(=O)CCc2ccsc2)CC1 +NC(=O)c1cccc(CC2CCN(C(=O)Cn3cccnc3=O)C2)c1 +CCn1c(=O)c2ccnn2c2ccc(C(=O)N3CCCC3)cc21 +CC(Nc1ccc2nnnn2n1)c1ccccc1F +CCCCNC(=O)N1CCCC(NS(C)(=O)=O)C1 +Cc1ccnc(C(NC(=O)c2cnc(-c3ccncc3)nc2)C2CC2)c1 +COc1ccc(C(=O)NCCCn2cccn2)nn1 +CN(Cc1ccc(F)cc1Cl)S(C)(=O)=O +O=C(c1ccc(CCC(F)(F)F)cc1)N1CCC(CO)C1 +CC(C)(CNC(=O)C1CCC(=O)N1)c1ccc(Br)cc1 +CSc1cc(C(=O)N2CCC(n3cccn3)CC2)ccn1 +O=C(Nc1nc(-c2ccc3c(c2)CCO3)cs1)c1ccsc1 +COc1ccc(NC(=O)N(C)Cc2ccccn2)cc1Cl +Cc1n[nH]c(CN2CCc3onc(-c4cccc(F)c4)c3C2)c1Cl +Cc1ccc(NC(=O)c2ccccc2S(N)(=O)=O)cc1 +Cc1ccc(C(=O)N2CCC3CC(C)OC3C2)cn1 +Cc1cc(C)n(CCCNC(=O)N(C)Cc2nccn2C(F)F)n1 +COc1cccc(C(=O)NCC(C(C)C)N2CCOCC2)c1F +CCN(CC)c1ccc(CCC(=O)N(C)C)cc1N +COc1cc(C#N)ccc1OC(C)C(=O)NC1CCC(C)CC1 +Cc1ccc(Nc2ccc(NC(=O)C(C)(C)C)cc2)nn1 +CNS(=O)(=O)Cc1ccc(CNC(=O)Nc2ccccn2)cc1 +CCOC(=O)C1(CNC(=O)Nc2cccc(C(C)=O)c2)CCC1 +Oc1ccc2c(c1F)C(Cc1cccc(F)c1)NCC2 +CN1CCC2(CCC1=O)CC(NC(=O)C1CC1)c1ccccc1O2 +Cc1nn(C)c2ncc(C(=O)NCC3CCCC(C)C3)cc12 +CCC(C)(NC(=O)c1cnc(C2CCCO2)s1)c1nccs1 +CC(C)(C)c1ccc(NC(=O)NCc2nnc3n2CCC3)nn1 +CCc1noc(CN(C)C(=O)c2ccc(-c3cscn3)cc2)n1 +NC(=O)c1ccc(COc2cccc(C(N)=O)c2)cc1 +CCn1nccc1NC(=O)COc1ccccc1Cl +O=C(COC(=O)Cc1cccs1)NC1CCCc2ccccc21 +COC(=O)CCNc1cc(C(C)=O)ccc1Cl +Cn1ncc2c1ncn1c(-c3ccccc3)nnc21 +O=C(c1cc(-c2csc(-c3ccoc3)n2)c[nH]1)N1CCCC1 +C#CCNC(=O)c1ccccc1NC(=O)C1CC2CCC1O2 +Cc1cccc(C)c1OCCc1nc(CC#N)cs1 +CCc1cc(OC)c(NCCN2CCOCC2)cc1OC +COc1cccc(-c2cn3c(nc4cc(N)ccc43)[nH]2)c1 +CCCOc1cccc(C(=O)Nc2ccncc2)c1 +Cc1cc(Cl)ccc1S(=O)(=O)NC(C)(C)CO +CCN(CC)c1ncc(CN2CCC(Oc3cccnc3)C2)s1 +C=CCN(CC=C)Cc1nc2cc(F)c(F)cc2[nH]1 +CC(=O)c1cccc(NC(=O)C(C)OC(=O)c2ccc(O)cc2)c1 +O=C(Cc1cccs1)NCc1nc(-c2ccc(F)cc2)n[nH]1 +CN(C)S(=O)(=O)N1CCN(C(=O)Nc2cn[nH]c2)CC1 +CC(C)(C)c1cc(C(=O)NCc2csc(=O)[nH]2)no1 +Cc1ccc(NC(=O)c2ccc(F)c(F)c2)cc1N +CNS(=O)(=O)CC(=O)N1CCCCC1c1ccc(C(C)C)cc1 +O=C(NCCN1CCOCC1)Nc1nc(Cc2ccccc2)cs1 +O=S(=O)(NCCCn1cccn1)c1cccc2cccnc12 +Cc1ccc(C(C)C)c(OC(C)C(=O)N(C)Cc2cc(C)on2)c1 +COCC(C)(NC(=O)c1ccc2ccccc2c1)C(=O)OC +CCOc1ncccc1CNC(=O)c1cc(OC)ccc1O +CCCC1CN(C(=O)Nc2ccccc2SC)CCO1 +CN(C)C(=O)CN1CCN(C(=O)Cc2c[nH]c3ccccc23)CC1 +CNC(=O)C(Sc1ccccc1)c1ccccc1 +NC(=O)NCC(=O)NCCOc1cccc(Cl)c1 +Cn1ccc2c1CN(c1ccc3nnc(C(F)(F)F)n3n1)CC2 +Cc1csc(C(=O)NCCCn2ccc3cccnc32)c1 +Cc1cccc(C(=O)NC(C)C(=O)N(C)Cc2c(C)noc2C)c1 +CCCc1noc(C2CCCCN2C(=O)Cc2cccs2)n1 +O=C(Nc1ccc(OC(F)F)cc1)c1ccc[nH]c1=O +CCCCN(CC(=O)Nc1ccon1)C(=O)C(C)(C)C +Cc1nc(C(N)c2cccc(F)c2Cl)sc1C +O=C(NC(c1ccc(F)cc1)C1CC1)c1cccnc1 +O=S(=O)(N1CC=C(c2ccccc2Cl)CC1)N1CCOCC1 +C=CCNC(=O)CSc1nncn1-c1ccc(OC)cc1 +CCCOc1ccc(C(=O)Nc2ccccc2C(=O)NCC)cc1 +COc1ccccc1CNC(=O)c1cn[nH]c1-c1cccs1 +Cc1nc(C(C)NC(=O)c2ccc(CCC(C)(C)O)cc2)n[nH]1 +CC(C)Cc1cc(C(=O)N(C)C(C)c2ccncn2)n(C)n1 +Cc1cc(C(=O)N2CCC(CSc3nccn3C)CC2)c(C)o1 +CCC(C)NC(=O)NC1CCCN(Cc2ccccc2)C1=O +COC(=O)C1CCCN(C(=O)c2nc(C)cc3c(N)cccc23)C1 +O=C(Nc1ccc(OC(F)F)c(F)c1)c1ccc2[nH]cnc2c1 +CCC1COCCN1CCC(=O)N1CCc2ccccc2C1 +CCCN(CC)c1ccc(C(=O)N2CCC(CNC(C)=O)CC2)cc1 +CCOC(=O)c1csc(NC(=O)Cn2cnc(C)cc2=O)n1 +CC(CC(=O)Nc1cccc(C#N)c1)NC(=O)c1ccccc1 +CCOCc1cccc(NC(=O)C2CCCN2C(=O)OC(C)(C)C)c1 +Cc1ccc2nc(SC(C)c3nc(C(C)C)no3)n(C)c(=O)c2c1 +COC(=O)CCN(C)C(=O)c1ccc(OC)c(F)c1 +CCOc1ncnc2c1CN(C1CCOC1=O)CC2 +COc1ccc(CCCCn2cc(N)cn2)c(C)c1C +O=C(Nc1cc(C2CCOCC2)[nH]n1)c1cccc(-c2ncon2)c1 +CCCN(CCC)C(=O)c1ccc(NC(=O)CC)cc1 +Cc1ccc(-c2n[nH]c(SCC(C#N)CCC#N)n2)cc1 +CC(C)(C)C(=O)NCCCC(=O)Nc1cc(F)c(F)c(F)c1 +Cc1cc(C(=O)N2CCCC2CO)c(C)cc1Br +CC(C)c1nnnn1CC(=O)Nc1cc(Cl)ccc1F +COc1cccc(C(=O)N2CCN(c3c(C)n[nH]c3C)CC2)c1 +CCc1sc(C(=O)NCCc2nc(C(C)C)no2)cc1C +O=C(CC1CCN(C(=O)c2ccccc2O)CC1)N1CCOCC1 +C=CCNC(=O)CSc1cc(C(=O)NC2CC2)c2ccccc2n1 +NC(=O)C1(CNC(=O)c2ccc(-c3cscn3)cc2)CCOCC1 +CCC(CCNC(=O)c1ccccc1)NC(=O)c1ccccc1 +CC(=O)Nc1ccc(SC(C)C(=O)N2CCc3ccccc32)cc1 +C=CCNc1nnc(SCc2cn3ccccc3n2)s1 +CCOC(=O)c1c(C)c(C)n(Cc2ccc(OC)c(OC)c2)c1C +O=C(OCC1CC=CCC1)c1cn(-c2ccccc2)nn1 +COc1ccnc(NC(=O)c2ccc(C(F)(F)F)nc2)c1 +CC1CCOCCN1S(=O)(=O)c1ccc(C#N)cc1Cl +COCC12CCCOC1CCN(C(=O)Cc1ccc3c(c1)OCO3)C2 +NS(=O)(=O)c1cccc(NC(=O)C2CCCCCC2)c1 +C=CCn1c(SCC(=O)NC2CCCCC2C)nnc1C1CC1 +CCN(Cc1cc(N)ccc1OC)c1cccc(C)c1 +COCCNC(=O)CNc1cccc(C(=O)N2CCCCCC2)c1 +Cc1c(Cl)c(C(=O)NC(C)CN2CCOCC2)nn1C +Cn1cc(-c2nn(C(C)(C)C)c3c2CNCC3)nn1 +Cc1ncc2c(c1-c1nnnn1Cc1ccccc1)CCC2 +CC1CN(C(=O)Nc2cccc(Cl)c2N(C)C)CCO1 +COCCn1cc(NS(=O)(=O)c2ccc(C)cc2)cn1 +Cc1nnc(COC(=O)CCNC(=O)c2ccco2)o1 +COc1ccc(Cl)cc1NC(=O)NCC(C)(O)C1CC1 +O=S1(=O)COCCN1Cc1cccc(Oc2ccccc2)c1 +Cn1cnc(CNC(=O)NCC2(c3ccc(Cl)cc3)CCCC2)n1 +CC(=O)NCCCNC(=O)NC1CCC(O)CC1 +Cc1cc(C(=O)Nc2ccc(OC(C)C)cc2)no1 +CCCS(=O)(=O)N(C)Cc1ccc(OC)cc1 +CCC(C)NC(=O)c1cc(C)c(C)c(S(=O)(=O)NC)c1 +CC(C)CC(C(=O)NC1CCC(=O)N(C)C1)N1CCCCC1=O +O=C(NCC(F)(F)F)c1nc2c(O)cccc2s1 +O=C(NCCCc1nc2ccccc2s1)Nc1cccnc1 +CC(C)c1ccc(C(=O)N2CCC(C(N)=O)C2)cc1 +CC(CN1CCCC1=O)Nc1ncnc2sccc12 +CC(C)(C)C(=O)N1CC(F)C(OCc2nc3ncccc3[nH]2)C1 +CCCS(=O)(=O)NCC1(O)CCOc2ccccc21 +O=C(CSc1nncs1)NCCOc1ccc2c(c1)CCC2 +Cc1cc(C)c(C(=O)Cn2cc(Br)cn2)cc1C +COc1ccccc1CCOc1cc(C)c(N)c(C)n1 +COC(=O)CCn1c(-c2ccc(N)cc2)nc2ccccc21 +Cc1ccc(NC(=O)C(C(C)C)N2CCCC2=O)cc1C(F)(F)F +CCOC(=O)C1CCN(S(=O)(=O)c2cnn(C)c2)CC1 +CC(NC(=O)CSc1ncnc2ccsc12)c1cccs1 +Cc1nn(C)c(C)c1CC(=O)Nc1ccnn1C(C)C +COc1ccccc1NC(=O)COc1ccccc1CO +COC(=O)Cn1ccn(-c2cc(C)cc(C)c2)c(=O)c1=O +CCc1nnsc1C(=O)N1CC(C)C(=O)Nc2ccccc21 +Cc1noc2nc(C3CC3)cc(C(=O)N3CCCC(C)CC3)c12 +Cc1csc(C2CN(CC(O)COc3ccccc3)CCO2)n1 +Cc1ccc(C(C)NC(=O)Nc2nnc3ccccn23)cc1F +Cc1noc(C)c1C(=O)Nc1nc(C2CC2)cs1 +CC(=O)Nc1ccc(CC(=O)N2CCOC(C)C2)cc1 +CC1CN(C2CCN(C(=O)NCc3ccnn3C)CC2)CCO1 +CCOc1ccc(C(C)NC(=O)c2cc(C)no2)cc1OCC +CCn1c(=O)n(CC(=O)N2CCOCC2)c(=O)c2ccccc21 +CCc1cccc(OC2CN(C(=O)CN3C(=O)OCC3C(C)C)C2)c1 +CCC(CO)NC(=O)c1ccc(S(=O)(=O)N2CCCCC2)cc1 +CCn1cccc(-c2nnc(NCC(C)C)s2)c1=O +CCC1CCCN(S(=O)(=O)c2ccc(CNC(C)=O)s2)C1 +CCCOC1CCCN(C(=O)c2cc3ccccc3[nH]2)C1 +CC(C)(CNC(=O)c1cccnc1OCC(F)F)c1ccncc1 +COC(=O)CCCN(C)C(=O)c1ccc2c(c1)Cc1ccccc1-2 +CCOCCCC(=O)Nc1ccc(-c2cn3cccnc3n2)cc1 +NC(=O)Nc1cccc(C(=O)OCc2ccc(Cl)cc2)c1 +CC(C)CCNC(=O)CN1CCN(c2ccc3c(c2)OCCO3)C1=O +CN(C)S(=O)(=O)c1ccc(C(F)(F)F)cc1 +O=C(NCc1ccccc1)c1noc(-c2ccc(F)cc2)n1 +COc1ccc(C2CCCN2C(=O)NCC2CCCO2)cc1OC +CC(C)CC(C)n1nccc1NC(=O)NCCC(=O)N(C)C +COc1ccc(C(=O)CCCC(=O)NC(C)(C)C)cc1F +Nc1ccc(F)c(NS(=O)(=O)c2ccccc2)c1 +Cc1ccc(C)n1-c1sccc1C(=O)NCCCN1CCOCC1 +Cc1ccc(CNC(=O)Nc2nnc(C)s2)cn1 +CC(NC(=O)N(C)Cc1nc2ccccc2c(=O)[nH]1)C1CCCO1 +CCCc1c(C(=O)OCC(N)=O)[nH]c(C)c1C(C)=O +O=S(=O)(NCc1ccc(F)cc1)c1cc(F)ccc1F +O=C(CCc1cnn(-c2ccccc2)c1)N1CCCS1(=O)=O +CC(=O)NC(C)C(=O)N1CCN(c2nnnn2-c2ccccc2)CC1 +Cc1ccc(Cn2cc(-c3noc(-c4ccncc4)n3)nn2)cc1 +CC(NS(=O)(=O)c1ccccc1F)C(O)c1ccc(F)c(F)c1 +O=S1(=O)N=C(NCC(O)c2ccc(F)c(F)c2)c2ccccc21 +CCOc1cccc(-c2ccc(CC#N)c(=O)n2C)c1 +COc1ccc(C(=O)Nc2cccnc2)cc1Cl +Cc1cccc(S(=O)(=O)NCC2CCCO2)c1 +CSc1cccc(NC(=O)Nc2cccc(NC(C)=O)c2)c1 +CCCNC(=O)C1CN(C(=O)C(C)C)CC1c1cccc(F)c1 +Cc1nn(C(C)C)c(C)c1NC(=O)CCn1c(=O)oc2ccccc21 +Cc1nn(C)c(C)c1NC(=O)c1cc(-c2c(C)nn(C)c2C)[nH]n1 +CCC(C)C(C)Nc1ccccc1S(N)(=O)=O +N#Cc1cccc(S(=O)(=O)NC2(c3cccc(Cl)c3)CC2)c1 +CCOc1ccccc1-n1c(Cc2cccnc2)n[nH]c1=O +CCc1cc(CNC(=O)CCn2cc(C)cn2)[nH]n1 +Cn1cc(S(=O)(=O)NCCC2CCCCC2)c(N)n1 +CCOC(=O)C=C(Nc1ccc2c(c1)OCO2)C(F)(F)F +O=C(OCCc1cccnc1)c1ccc(-n2ccnc2)cc1 +Cc1cnc(CNC(=O)NC2COc3c2ccc(C)c3C)s1 +O=C(Nc1nc(-c2ccccc2)ns1)c1ccc2c(c1)OCO2 +Nc1cccc(OCc2nc(-c3ccsc3)no2)c1 +O=C(NCc1ccccn1)C1CCC(=O)N(C2CCCCCC2)C1 +COc1cc(-n2cnc3cc(-c4ccncc4)ccc32)ccc1O +COc1ccc(NC(=O)c2cncc(C)c2)cc1CO +CC(Oc1ccc(Cl)cc1)C(=O)Nc1cccc(C(=O)N(C)C)c1 +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1ccc(Cl)cc1 +CCC1c2ccsc2CCN1C(=O)CNc1ccc(C#N)cc1 +COCC(NC(=O)NC1(C)Cc2ccccc2C1)c1ccc(C)o1 +Cc1cc(C(=O)NC2CCCCC2)nc(N(C)C)n1 +CC(C)OC(=O)c1cccc(-c2nnn(CCC#N)n2)c1 +CS(=O)(=O)N1Cc2nccn2CC(COCC2CC2)C1 +CCC(=O)Nc1cc(Cl)ccc1C(=O)N1CCCC1 +N#Cc1cccc(NC(=O)c2ccc(O)cc2F)c1 +CCOC(=O)c1c(NC(=O)c2cc(C)on2)sc(C(C)=O)c1C +CN(Cc1cccnc1)C(=O)Nc1cc(Cl)cc2c1OCC2 +COc1ccc2oc(=Nc3ccc(F)cc3)c(C(N)=O)cc2c1 +O=C(CC1COc2ccccc2O1)Nc1ccccn1 +O=C(CC1CCCO1)NC1CCCc2[nH]c(=O)ccc21 +CCCCNc1ncnc(Nc2nc(C)c(C)s2)c1N +c1ccc(-n2nnnc2NCCc2ccco2)cc1 +CSc1ncccc1C(=O)N1CCC(Oc2cccc(F)c2)CC1 +CCOC(=O)N1CCN(CCOc2cccc(N)c2)CC1 +CCCOc1nccnc1NC1CCN(C(=O)c2ccccn2)CC1 +CCc1cnccc1C(=O)NCC(=O)Nc1ccc(-n2cccn2)cc1 +COc1ccc(NC(=O)N2CCN(c3ccc(F)cc3)CC2)cc1 +Cc1n[nH]c(C)c1S(=O)(=O)N1CCCC(C(=O)NC(C)(C)C)C1 +N#Cc1ccc(Cn2cc(Br)ccc2=O)cc1 +Cc1cc(=O)n(CCNS(=O)(=O)c2ccccc2)cn1 +CCNC(=O)Cc1c(C)nn(-c2nc(C)cc(C)n2)c1C +COc1ccc(S(=O)(=O)c2cnc(N)nc2)cc1C +CC(C)(C)c1nnc(NC(=O)NC(C(N)=O)C(C)(C)C)s1 +CCCCCCNC(=O)N1CCN(c2ncccc2C#N)CC1 +Cc1ccc(C)n1N(C)c1ccc(C(F)(F)F)cn1 +Cc1cccc(CC(=O)NCCS(=O)(=O)N2CCOCC2)c1 +CNC(=O)CN(C)c1nc2c(OC)cccc2s1 +COc1nn(C)cc1C(=O)N1CCC(C(=O)NCc2ccco2)CC1 +c1cnc(-c2nc(COc3ccc(-c4nnco4)cc3)cs2)nc1 +CC(C)(O)CN1CCN(C(=O)C2CCN(c3cnccn3)CC2)CC1 +COCC(=O)N1CCC(c2nc3ccccc3cc2NC(C)=O)CC1 +Cc1occc1C(=O)N1c2ccc(F)cc2CCC1C +COC(=O)c1ccc(Cn2cnc3c(oc4ccccc43)c2=O)s1 +Cc1noc(C)c1Cn1c(=O)n(C)c2ccccc21 +O=C(Nn1cnnc1)c1cc2ccccc2oc1=O +CC(CC(N)=O)C(=O)Nc1cccc(Cl)c1Cl +CCOc1ccc2c(c1)CN(C(=O)c1ccccn1)CC2 +CCNC(=O)N1CCN(c2ncccc2Cl)CC1 +N#Cc1cccc(C(=O)Nc2ccccc2C(F)(F)F)c1 +O=C(Nc1ccc2c(c1)CCC(=O)N2Cc1ccccc1)c1ccco1 +Cc1cccc(CNC(=O)c2ccc3c(c2)NC(=O)CO3)c1 +Cc1cc(C(=O)Nc2cc(S(C)(=O)=O)ccc2F)c(C)s1 +CC(CC1CC(C)(C)OC1=O)C(=O)Nc1cc(Cl)ccc1Cl +COc1cccc(OC)c1OCc1ccc(CO)o1 +CC(C)Oc1nnc(SCC(=O)c2ccccc2)s1 +CC1CN(C(=O)C2CC2c2ccccc2OC(F)(F)F)C(C)CO1 +O=C(NCc1cc2ccccn2n1)c1ccc(F)cc1 +O=C(NCc1ccccc1Cl)C1CC(=O)N(CC(F)(F)F)C1 +CC(C)CCOCCOc1ccc(N)cc1Cl +CC(C)(C)c1nnc(CN(CCc2cccc(F)c2)C2CC2)o1 +Cn1c(N)c(N2CCN(C(=O)c3ccco3)CC2)c(=O)[nH]c1=O +CC1(C)C2CCC1(C)C(NC(=O)CCCNC(=O)c1ccsc1)C2 +CSc1ncccc1C(=O)Nc1cc(C)ccc1F +CN(C(=O)c1[nH]ncc1Br)c1cccc(C#N)c1 +CCn1c(C(=O)NCC(=O)NC(C)C)cc2sccc21 +O=C(NCCCOC1CCCC1)c1c[nH]c2ccccc2c1=O +CCN1CC(C(=O)Nc2nc(-c3cccnc3)cs2)CC1=O +C=CCNC(=O)c1ccc(NC(=O)N2CCC(CO)CC2)cc1 +CC(=O)c1cnc(-c2ccc3c(c2)OCCO3)s1 +CCC(=O)c1cn(CC(=O)NCc2ccco2)c2ccccc12 +COc1ccc(NC(=O)CCCNC(=O)c2ccc(F)cc2F)cn1 +CCc1ccc(CNC(=O)Cn2cnnn2)s1 +O=C(NCc1cn[nH]c1)c1ccc(F)cc1Br +Cc1ccc(C(C)NC(=O)Cn2cc(Cl)cn2)cc1C +CN(CCOc1ccc(F)cc1)C(=O)NCCN1CCOCC1 +Cc1cc(C)cc(NCc2cn(C)nc2-c2ccncc2)c1 +N#Cc1nc(NCC2(O)CCOCC2)ccc1Cl +Cc1ccc(NS(=O)(=O)c2ccc(-c3[nH]nc(C)c3C)o2)cc1 +CCCCS(=O)(=O)N(C)C(C#N)c1ccccc1 +CN(C)C(=O)c1cc(OC2CC2)ccc1C(C)(C)C +CNC(=O)c1ccc(NC(=O)NC(C)C(=O)NC(C)(C)C)c(C)c1 +COC(=O)C1CCN(C(=O)c2ccncc2F)CC1 +CC1CN(C(=O)c2ccns2)CC1(O)C1CC1 +FC(F)CN1CCN(CCOc2ccc(Cl)cc2)CC1 +O=C1N(c2cccnc2)CCC12CCN(c1ncc(F)cn1)CC2 +Cc1ccccc1NC(=O)c1ccc(S(=O)(=O)N(C)C2CC2)cc1 +Cc1ncc(C(C)NC(C)c2ccc(-n3cccn3)cc2)s1 +Cc1ccc(-c2nnn(CC(=O)N3CCc4ccccc43)n2)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)NCc1ncccc1F +Cc1cnn(C2CCCN(C(=O)c3cncn3-c3ccccc3)C2)c1 +Cc1ccc(S(=O)(=O)n2c(=O)oc3ccc(Cl)cc32)cc1 +Cc1ccc(-n2ncc3c(N4CCC(C)CC4)ncnc32)cc1 +O=C(NCC(F)(F)F)c1c(F)cccc1Cl +Cc1cc(C)c(NC(=O)CCN2C(=O)COc3ccccc32)c(C)c1 +CCCCCCNC(=O)Nc1ccc(Cl)c(C(=O)N(C)C)c1 +NC(=O)C1CN(c2nc(-c3ccc(Cl)cc3)no2)CCO1 +Cc1ccc(OCCC(=O)NCc2n[nH]c(C)n2)cc1 +Cc1ccc(F)c(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)c1 +CCC(C)OC(=O)C(C)Oc1ccccc1C(C)=O +CC(=O)Nc1ccccc1OCc1ccccc1C#N +CN(CCO)C(=O)Nc1ccc(C(=O)Nc2ccccc2)cc1 +CCOC(=O)C1CCCN(C(=O)Cn2cnc(C(C)C)cc2=O)C1 +NC(=O)CC1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 +CCNC(=O)N1CCOC(c2ccccc2Br)C1 +O=C(COC(=O)c1ccc(O)cc1)Nc1ccc(Cl)cn1 +Cc1ccsc1C(O)CNC(=O)COc1ccccc1 +Cc1nn(C)c(C)c1CCNC(=O)C1Oc2ccccc2OC1C +O=S(=O)(c1ccccc1)c1ccc(NCc2ccco2)nn1 +CCOC(=O)C(C#N)c1ccc(OC)c(Cl)c1 +C#CCNC(=O)c1ccc(C)c(S(=O)(=O)N(CC)CC)c1 +O=C(Nc1ccc(Cl)cc1)c1cc(Br)c[nH]1 +Cc1cc(NC(=O)CN(C)c2ncnc3c2cnn3CCC#N)no1 +O=C(Cn1nnnc1C(c1ccccc1)N1CCOCC1)N1CCC1 +O=C(CNC(=O)NCc1ccccc1)Nc1ccccc1F +CCc1nn(C)cc1CNc1cccnc1-n1cccn1 +CCCCc1ccc(NC(=O)CCc2c(C)nc(C)[nH]c2=O)cc1 +O=C(CS(=O)(=O)c1ccc(F)c(F)c1)Nc1ccc(F)cc1F +Cn1cnnc1-c1ccc(NC(=O)COc2ccccc2C#N)cc1 +COc1cc(OC)c2c(c1)C(C(=O)N1CCCC1)CC2=O +O=C(NC1CC1)c1nc(-c2ccc3cc[nH]c3c2)no1 +CCOCC1CCCN(C(=O)c2ccc(SCC)nc2)C1 +CCOC1CC(NC(=O)Cn2cccn2)C12CCCC2 +Cc1ncc(C(C)NCCc2cc(Cl)c3c(c2)OCCO3)s1 +COc1cccc2c1OCC(NC(=O)c1cccc3ccc(C)nc13)C2 +Cc1nc(CN2CCOCC3(CCN(c4ncccn4)C3)C2)cs1 +Cc1n[nH]c(C(=O)Nc2ccnn2C(C)C)c1Br +CCOC(=O)c1cc(NC(=O)NC(C)c2c(C)noc2C)cn1C +CC(NC(=O)c1cccc(C#N)c1)c1nc2ccccc2[nH]1 +CCc1noc(C)c1C(=O)N1CCN(CC)CC1 +Cc1cccc(OCCC(=O)N2CCC(O)CC2)c1C +COc1cccc(CNC(=O)c2scnc2C2CC2)c1OC +CCC(C)N(C)S(=O)(=O)c1cccc(S(N)(=O)=O)c1 +CCCn1nc(CO)cc1-c1ccc(OC)c(F)c1 +O=C(CCn1cnc2ccccc2c1=O)N1CCC2(CC1)OCCO2 +CCCNS(=O)(=O)c1c(C(=O)OCC)c(C)n(C)c1C +Cc1cc(C(=O)N2CCC(Cn3cccn3)CC2)c2cccc(C)c2n1 +NC(=O)c1ccc(NC(=O)Cc2ccc3ccccc3c2)cc1 +Cc1cnc(NC(=O)CCc2ccccc2F)s1 +Cc1nccn1-c1ncccc1NC(=O)c1cn[nH]n1 +COC(=O)c1cccc(-n2nnc(CO)c2C2CC2)c1 +N#Cc1c(Cn2c(=O)oc3cc(Cl)ccc32)cn2ccccc12 +CCCNC(=O)CNc1cccc(C(=O)N2CCOCC2)c1 +Cc1cc(Cl)cc(C(=O)Nc2ccsc2C(N)=O)c1 +Cc1ccc(OCC(=O)Nc2cccc(-n3cnnn3)c2)c(C)c1 +Cc1ccc(S(=O)(=O)NC(=O)NCCC(=O)N2CCCC2)cc1 +O=C(NCC1(CCO)CCCCC1)c1ccnc(OC2CCC2)c1 +Cc1cccc(CNC(=O)COC(=O)c2ccccc2F)c1 +COc1ccccc1CC(C#N)C(=O)Nc1ccccc1OC +CCOC(=O)COC(=O)c1ccc(Br)cc1Cl +Cc1nc(CSc2nnnn2-c2ccccc2)nc2ccccc12 +NS(=O)(=O)c1ccc(Cl)c(C(=O)OCC2CCCO2)c1 +C=C(C)CN(CC)C(=O)C(C)Nc1ccc2c(c1)CCN2C(C)=O +COc1ccc(OC)c(NC(=O)Nc2cc(C)nn2C)c1 +CC(C)Oc1ccc(CNC(=O)c2cn[nH]c2-c2ccccc2)cc1 +O=C(NCCN1CCCCCC1=O)c1cn(-c2ccccc2)nn1 +CCCN(Cc1ccccc1)C(=O)Cn1c(C)c(C)sc1=O +CC(C)Nc1cccc(CNC(=O)c2ccncc2)c1 +CSc1nccn1-c1cccc(C(=O)Nc2nccn(C)c2=O)c1 +Cc1ccc(NC(=O)N2CCN(S(C)(=O)=O)CC2)cc1C +COCCNC(=O)C1CCCN(c2cn[nH]c(=O)c2)C1 +CCCC(=O)Nc1cccc(CNC(=O)NC2CC2)c1 +O=C(Nc1cccc(F)c1)N1CCc2nc3ccccn3c(=O)c2C1 +COCCOc1ccc(NC(=O)Cc2c(C)nc(C)[nH]c2=O)cc1 +COCCOC(=O)C1=C(C)C(C(=O)N(C)c2ccccc2)=NC1C +Cc1onc(-c2cccnc2)c1C(=O)N1CCC2(CC1)OCCO2 +Cc1nnc(SCC(=O)N2CCc3ccccc32)n(N)c1=O +CCC(NC(=O)c1ccoc1)C1CN(Cc2ccccc2)CCO1 +Cc1cc(C)c(NC(=O)Cc2nc3ccc(C)cc3c(=O)[nH]2)c(C)c1 +CC1CCCCN1C(=O)COC(=O)c1n[nH]c2ccccc12 +COc1ccc(-c2sc(NC(C)=O)nc2C)cc1OC(C)C +COCC(C)N1CCN(C(=O)C(C)OC2CCCC(C)C2)CC1 +COc1coc(C(=O)NCCCc2ccccc2)cc1=O +CCOC1CCN(C(=O)Nc2cnc(C(C)(C)C)nc2)CC1 +Cc1c(C(=O)Nc2ccccc2C(N)=O)cnn1-c1ccc(F)cc1 +CCc1nc(CNc2ccc(-c3nccc(C)n3)cc2)cs1 +N#CCC(=O)COc1ccc(Br)cc1 +O=S(=O)(NCCCO)c1ccc(F)c(F)c1F +Nc1cccc2c1CN(c1ccc(Cl)cc1)C2=O +CC1=NC(C(=O)N2CCCC(C(=O)NCCC(C)C)C2)C(C)=C1C +CN1C(=O)C2(CCN(C(=O)CO)CC2)C1c1ccccc1 +CCS(=O)(=O)c1ccc(NC(=O)N2CCCC(O)C2)cc1 +Cn1c(C2CC2)nc2cc(NC(=O)c3cc(Cl)c[nH]3)ccc21 +CCN(Cc1ccc(C#N)cc1F)C(=O)c1cccc(C)c1 +Cc1nn(C)c2cn(C(C)C(=O)N(C)Cc3cccs3)nc12 +CC(CC(=O)c1ccccc1)NC(=O)c1scnc1C1CC1 +CC(C)NC(=O)COC(=O)c1cnn2c(-c3ccccc3)ccnc12 +CCn1nnc2cc(C(=O)OCC(=O)NC3CCC(C)CC3)ccc21 +CN(CC(=O)NC1CCCC1)S(=O)(=O)c1ccccc1F +CC(C)n1ncc2cc(C(=O)N3CCOCC3)cnc21 +CCOC(=O)CN(C)C(=O)c1c(C)noc1C(C)C +Cc1nc(C(C)N(C)C(=O)Cn2cc(C)c(=O)[nH]c2=O)c(C)s1 +COc1ccccc1NC(=O)Cn1nnc(-c2ccccc2)n1 +CSc1ccc(Cl)c(C(=O)Nc2cccc(S(C)=O)c2)c1 +COc1ccc(F)c(NC(=O)C(NC(=O)CC(C)C)C(C)C)c1 +Nc1ccc(C2NCCc3cc(Cl)cc(F)c32)cc1 +CCS(=O)(=O)N1CCCC1C(=O)c1cc(C)ccc1C +CCCC(CCC)N1Cc2c(C(=O)OC)cc(N)cc2C1=O +Cn1c(=O)cc(C(=O)Nc2cccc3[nH]ccc23)c2ccccc21 +COc1ccc(OC)c(NC(=O)Cn2nccc2-c2ccncc2)c1 +CCOc1ccccc1N1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1ccncc1NC(=O)N(C)CC1CCCCO1 +FC(F)(F)CNC(CC1CCOC1)c1ccccc1 +O=C(NC1C2CC3CC(C2)CC1C3)c1ccc(N2CCCC2=O)cc1 +CNC(=O)c1cccc(NC(=O)Cc2c[nH]c3c(C)cccc23)c1C +Cc1ccccc1-c1noc(=O)n1CC(=O)c1cnn(C)c1 +Cc1cc(C)cc(NCc2nnc3n2CCCCC3)c1 +CN(Cc1ccc(F)cc1)c1ncnc2sccc12 +CN1C(=O)CC(C(=O)Nn2cnc3ccccc32)C1c1cccnc1 +Cc1ccc(C(N)=O)cc1NC(=O)CSc1nncs1 +CC(C)c1ccc2c(c1)C(=O)CC(C(=O)N1CCN(C)CC1)C2 +CSc1ccc(C=Cc2nc3c(cnn3C)c(=O)[nH]2)cc1 +CCC1CCCCN1S(=O)(=O)c1cc(OC)c(OC)cc1F +Clc1ccc(-c2nc3ccccc3[nH]2)cc1-n1cnnc1 +Cc1nc(-c2ccc(NCc3csnn3)cc2)cs1 +COCCOc1c(Cl)cc(NC(=O)c2ncoc2C)cc1Cl +CC(=O)NC1CCN(S(=O)(=O)c2ccc(C)c(C)c2)CC1 +CCn1ccc(C(=O)Nc2nnc(Cc3ccc(C)cc3)o2)n1 +CC(=O)Nc1ccc(NC(=O)c2noc3c2CCCCC3)cc1 +CCCCNc1nc(-c2cc(C)nn(CC)c2=O)cs1 +COc1cccc(C(NC(=O)c2ccsc2)c2nccn2C)c1 +CCOC(=O)c1c(C)c(C(=O)Nc2ccc(OC)cc2)c(C)n1C +Nc1cnn(CCCc2ccc3nc(C4CC4)[nH]c3c2)c1 +Cc1c(CN2CCN(Cc3ccc(F)cc3)C(CCO)C2)cnn1C +O=C(c1cccc(-n2cccc2)c1)N1CCN(c2ccc(F)cc2)CC1 +CCCNC(=O)c1ccc(N2CCN(S(=O)(=O)CC)CC2)nc1 +COc1ccc(OCCS(=O)(=O)N=c2[nH]c(C)c(C)s2)cc1 +COc1ccc(C(=O)C2CC2)cc1S(=O)(=O)NC(C)(C)C +O=C(Nc1ccccc1)Nc1cccc(CNC(=O)c2ccncc2)c1 +CC1(C)CN(C(=O)Nc2ccc(N3CCCC3=O)cc2)CCO1 +CC(C)(C)C(=O)CSc1nnc(-c2cnccn2)s1 +OCCNc1nc2ccccc2n1CCOc1ccccc1Cl +Cc1csc(CNC(=O)c2cccnc2N2CCCC2)n1 +CC(C)(C)c1ccc(C(=O)NCCC(=O)N2CCOCC2)cc1 +COCc1ccc(C(=O)Nc2ncccc2C)cc1 +CC(C)n1ncc2c1NC(=O)CC2c1ccc(-c2ccccc2)o1 +Cc1cccc(OCC(C)NC(=O)c2nccnc2N)c1 +COc1ccc(C(C)=O)cc1CC(=O)NC1(C#N)CCCCC1 +CC(C)c1nnc(SCC(=O)Nc2ccc(F)cc2)o1 +CC(OC(=O)c1cnn(C(C)(C)C)c1)c1ccc2c(c1)OCCO2 +Cc1cc(NC2CCC(O)CC2)n2nc(C(F)(F)F)nc2n1 +Cc1nc2scc(-c3ccco3)c2c(=O)n1CC#N +Cc1cc(C)n2ncc(C(=O)NCC(C)N3CC(C)OC(C)C3)c2n1 +CCN1C(=O)C(Cc2ccc3c(c2)OCO3)Oc2cc(O)ccc21 +CCN(CC(=O)OC)C(=O)CSc1ccc(C)cc1 +O=C(CCCc1nnc(-c2ccccc2)o1)NCc1cscn1 +Cc1nnc(CN(CCCO)c2ccccc2)n1C +CCc1nc(Cn2nnc(-c3ccc(C(N)=O)cc3)n2)cs1 +COCCN(Cc1ccco1)C(=O)Nc1ccc(F)cc1Cl +O=c1[nH]nc(C(O)c2ccccc2)n1Cc1ccco1 +N#Cc1ccc(Cn2nnc3cc4c(cc3c2=O)OCCO4)cc1 +CC(OC(=O)c1cc(C(C)C)nc2c1cnn2C(C)C)C(N)=O +CCN(CC(=O)Nc1cc(C)no1)c1cc(C)cc(C)c1 +Cc1ccc(N(Cc2ccco2)S(=O)(=O)c2cn(C)c(C)n2)cc1 +CC(C)N(Cc1ccc(C#N)cc1)C(=O)c1cc(=O)c2ccccc2[nH]1 +Cc1csc(CN(C)Cc2ccc(-n3cncn3)cc2)n1 +CN(CCN(C)C(=O)OC(C)(C)C)C(=O)Nc1ccc(F)c(F)c1 +CCC(NC(=O)CCC1CCCO1)c1nc(-c2ccccc2)c[nH]1 +CC(NC(=O)c1scnc1C1CC1)c1ccc(-n2ccnc2)cc1 +CCN(CC)C(=O)NC(C)c1cccc(S(=O)(=O)NC)c1 +CCCN(CCC)C(=O)CN1CC(C)OCC1C +Cc1cc2nc(-c3ccccc3)cc(NCCn3nc(C)nc3C)n2n1 +CCc1nc(C(=O)Nc2cccc(OCCn3cncn3)c2)co1 +O=C(CSc1nccc(=O)[nH]1)Nc1cccc(F)c1 +COc1ccnc(NC(=O)CSc2nccc3ccccc23)c1 +CCCC(=O)N1CCCC1C(=O)NCc1cccc(OC(F)F)c1 +CC(C)COC(=O)c1cccc(OCC(F)F)n1 +Cc1ccc(NC(=O)c2nc3ccc(N)cc3s2)cc1C +CC(C)C1CN(C(=O)c2n[nH]cc2Cl)CCC(=O)N1CC1CC1 +CC(=O)Nc1cc(F)c(F)cc1NC(=O)C1CCCc2ccccc21 +CC(CNc1ccccc1)NC(=O)c1ccc(-n2cnnc2)cc1 +O=C(Cc1ccc(F)cc1)NCc1cn2ccsc2n1 +O=C(NC1C(c2ccc(C(F)(F)F)nc2)CC(O)C1O)C1CCC1 +Cn1cc(NC(=O)NCCCCOc2ccc(F)cc2)cn1 +Cc1ccc(C(CNC(=O)c2scnc2C)N2CCOCC2)o1 +CN(CCCOc1ccc(F)cc1)S(=O)(=O)c1cccs1 +CNc1ncccc1C(=O)N(Cc1ccc(SC)cc1)C1CC1 +CC1Oc2ccc(C(=O)N3CCC(O)CC3)cc2NC1=O +CC(C)c1ocnc1C(=O)N1CCOC(c2ccc(Cl)cc2)C1 +CC1=NC(=O)C(CC(=O)NC(C)Cc2ccccc2Cl)C(C)=N1 +COc1ccc(Cl)cc1-n1ccnc1SCC#N +CCN(CCC#N)C(=O)c1cccc(OC)c1OC +O=C(Oc1ccc(Br)cc1)c1ccc(=O)[nH]c1 +CNC(=O)c1cccc(CNC(=O)c2cccc(OCC(F)F)n2)c1 +O=C(CCc1c[nH]c2ccccc12)Nc1cc(C(F)(F)F)c[nH]c1=O +CNC(=O)c1cc(S(=O)(=O)Nc2ccccc2OC)ccc1C +CC(=O)c1sc2ncn(CCCO)c(=O)c2c1C +CC(C)(CC(=O)NCc1cccc(C(F)(F)F)c1)n1cccc1 +CCC(C)N(Cc1ccccc1)C(=O)c1cc2c([nH]c1=O)CCCC2 +Cc1cccc(C(=O)Nc2ccccc2C(=O)Nc2nccs2)c1 +Cc1cnc2c(c1NCCCc1ccccc1)c(=O)n(C)c(=O)n2C +CC(C)(C)CC(=O)N1CCCN(C(=O)c2cccc(Cl)c2)CC1 +Cc1ccc(C(=O)c2c(Cl)cccc2Cl)cn1 +CC(=O)N1CC2c3ccccc3C(NC(=O)Cc3ccsc3)C2C1 +CCOC(=O)N1CCN(c2ncc(Br)cn2)CC1 +COCc1cc(C(=O)NC(C)C(C)(C)C)ccc1F +Cn1nc(CNC(=O)c2ccc(Cl)cc2)c2c1CCOC2 +Cc1ccc(N2CCN(C(=O)CCc3ccccc3)CC2=O)cc1 +COc1ccc(OCCCC(=O)N(C)C(C)C)cc1 +Oc1cc(OC(F)(F)F)c2c(c1)C(C1CC1)NCC2 +C#CCN1CCN(CC(=O)Nc2sc(C)c(C)c2C#N)CC1 +Cn1nccc1NC(=O)COc1ccccc1C#N +CC(C)(C)n1cc(NC(=O)Cn2nnc3ccccc3c2=O)cn1 +N#CC(NC(=O)c1ccc2nncn2c1)c1ccc(F)cc1F +Nc1ccc(C(=O)Nc2cccc3cn[nH]c23)cc1 +CCN(C)S(=O)(=O)c1c(F)cc(NC(C)=O)cc1F +CC(=O)N1CCC(C(=O)OCC2CC2(Cl)Cl)CC1 +COCCN1CC(C(=O)N2CCC(C)CC2C)CC1=O +NC(=O)Cc1ccc(NC(=O)c2cccc3ccccc23)cc1 +CC(C)(C)OC(=O)N1Cc2cnc(C(C)(C)C)nc2C1 +COc1cc(CNC(=O)Nc2nncs2)ccc1O +Cc1cc(C(=O)NCC(C)Oc2ccccc2)c(C)o1 +CCCNC(=O)CSc1ccc(-c2ccncc2)nn1 +CC(C)NC(=O)N1CCC(C(=O)NCc2ccc(F)cc2)CC1 +CCC(C)CS(=O)(=O)c1nnc(C2CC2)n1C +COC(=O)C(CNC(=O)c1nccn2ccnc12)CC(C)C +CCc1ccc(NC(=O)c2cnc3cc(C(C)=O)[nH]c3c2)cc1 +CC(=O)c1ccc(N2CCN(Cc3ccccc3)CC2)cc1 +NC(=O)C(Nc1ccc2nnc(C(F)(F)F)n2n1)c1ccccc1 +CC(C)C(C#N)N(C)C(=O)c1ccc(Cl)cc1 +COc1ccnc(NC(=O)c2cc(-c3ccc4c(c3)CCO4)no2)c1 +COCc1ccc(C(=O)N(CC2CCCO2)c2ccncc2)cc1 +Cc1ccc(Cl)c(NC(=O)CSc2nnnn2C)c1 +CN(C(=O)C1CC1(Cl)Cl)c1ccc(F)cc1 +O=C(Nc1ccncc1)NC1CCOc2c(Cl)cccc21 +CCCOC(=O)c1cc(NC(=O)c2ccco2)ccc1O +COC(=O)c1cc(Cl)ccc1Oc1cc(=O)n(C)c(=O)n1C +CC(Cc1ccccc1)OC(=O)C(C(C)C)N1CCCC1=O +COC(=O)Cc1cc(Br)ccc1C(=O)OC +COc1ccc(CNC(=O)c2cccc(C#N)c2)cc1OC +CC1CCN(C(=O)CN(C)S(C)(=O)=O)c2ccccc21 +Cc1ccc(C(=O)CNC(=O)c2c(F)cccc2Cl)cc1 +Cc1ccc(CN(C)Cc2nnc(-c3ccccc3Cl)o2)s1 +CC1Cc2ccccc2N1C(=O)CNS(=O)(=O)Cc1ccccc1 +N#Cc1cccc(NC(=O)CCC(=O)c2cccs2)c1 +COC(CNC(=O)C1CCN(S(C)(=O)=O)CC1)c1ccsc1 +CC(=O)N1CCc2ccc(NC(=O)Cc3cccc(C)c3)cc21 +CC(=O)NCCNC(=O)C(C)Oc1ccc(Br)cc1 +COCc1c(C(=O)N(C)Cc2cccc(-n3cccn3)c2)noc1C +Cc1nc(NC(=O)N(CCCO)CC(C)(C)C)sc1C +CC(=O)NC(Sc1ccc(Cl)cc1)C(=O)c1cccs1 +CCCCN(Cc1ccco1)C(=O)c1cc2c([nH]c1=O)CCCC2 +Cc1cc(C)n(Cc2nn3c(C4CC4)nnc3s2)n1 +CCOc1cc(F)ccc1NC(=O)c1nc2nccc(C)n2n1 +Cc1ccc2oc(=O)n(CC(=O)NC(c3cccs3)C(C)C)c2c1 +Cc1cc(NC(=O)c2ccc(Cl)cc2O)[nH]n1 +CCCNC(=O)CSc1nc(C)nc2sc3c(c12)CCC3 +C#CCOC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +CSc1nnnn1-c1cccc(NC(=O)NCC(C)(C)C(N)=O)c1 +COc1ccc(-c2csc(-c3nonc3N)n2)cc1 +Cc1cc(C(=O)N2CCN(CCCc3cnn(C)c3)CC2)on1 +CC(C)c1cc(C(=O)NCc2ccc3c(c2)OCCO3)n[nH]1 +CCOC(=O)Cc1csc2nc3[nH]ncc3c(=O)n12 +CCCCNC(=O)c1ccc(N2CCNC2=O)c(C)c1 +CN(Cc1ccco1)C(=O)c1cc2cc(Br)ccc2[nH]1 +O=c1c2ccccc2ncn1CC(O)COc1ccccc1 +CC1CN(C(C)(C)CNC(=O)C2CC2c2ccccc2)CC(C)O1 +Cc1nn(CC(F)(F)F)c(C)c1C(C)NC(=O)N(C(C)C)C1CC1 +CCn1nccc1C(C)NS(=O)(=O)c1ccc(C)cc1 +CC1CCCN(C(=O)NCCCOCC2CCCO2)C1 +CNC(=O)NCCc1ccccc1Br +O=C(C1CNc2ccccc2O1)N1CCC(O)CC1 +Cc1ccc(NC(=O)c2cccc(-c3nnnn3C)c2)cc1C +c1ccc2c(SCCn3cccn3)nncc2c1 +CCc1nc(C(C)NCc2nnnn2-c2ccccc2)cs1 +CCCC(C)NS(=O)(=O)c1ccccc1Cl +CCn1nc(C)c2ncnc(NCc3ccc4c(c3)OCO4)c21 +O=C(NCCCN1CCOCC1)c1ccc(-c2cccnc2)nc1 +CC(=O)N(C)C1CCN(C(=O)NCCSc2ccc(C)cc2)CC1 +Cc1ccccc1-c1ncc(C(=O)N2CCCC(C)C2)c(N)n1 +CCN1C(=O)C(O)(CC(=O)c2ccc(OC)cc2)c2ccccc21 +COc1cc(C)c(C)cc1-c1cc(C(C)=O)c(=O)n(C)n1 +CCOc1ccc(NC(=O)NCC2CCOC2)cc1F +C=CCOc1cccc(NC(=O)N2CCCC(O)C2)c1 +CCN(C)C(=O)C1CC(=O)N(c2cccc3ccccc23)C1 +COc1ccc(Nc2ncnc(Nc3cc(C)on3)c2N)cc1 +Fc1ccc(OCc2nnc(C3CC3)o2)c(Br)c1 +CC(=O)c1cc(-c2ccc(S(C)(=O)=O)[nH]2)c[nH]1 +CCCNC(=O)C1CCC(=O)N(C)C1c1ccc(F)cc1 +CC(C)(C)OC(=O)N1CCN(C(=O)Cc2cccc(O)c2)CC1 +Cc1cc(C)cc(OCc2nnc3n(C)c(=O)c4ccccc4n23)c1 +COC(=O)c1ccc(OC(=O)c2csc(C)n2)cc1 +Cc1nnc(SCC(=O)Nc2ccc(F)cc2Cl)s1 +Cc1nn(C)c(C)c1CNC(C)Cc1ccsc1 +COCCN(CCC#N)C(=O)c1oc2c(C)ccc(C)c2c1C +CCOC(=O)c1c(C2CCC2)nn(-c2ccncn2)c1N +O=C1COc2cc(NC(=O)NCCC3CCCCC3)ccc2N1 +CCc1nsc(N2CCN(Cc3cccn3C)CC2)n1 +Cc1noc(NC(=O)c2oc3c(C)ccc(C)c3c2C)n1 +Cc1ccc2c(c1)-c1nc3nc(N)[nH]c(=O)c3cc1C(O)O2 +CC(C)Oc1ccccc1OCCCn1cnc2ccccc2c1=O +CN(Cc1csc(C#CCO)c1)C(=O)NC1CC1 +CCC(C)NC(=O)CNc1cccc(Br)c1 +C=CCNC(=O)CN(c1ccc(Cl)cc1C)S(C)(=O)=O +CCOCC(=O)OCc1c(C)nn(-c2ccccc2)c1C +O=C(Nc1ccccn1)NC1CCc2cc(Cl)ccc21 +C=CCNS(=O)(=O)c1cc(C)c(C)cc1OC +Cc1ccc(C(=O)N2CCN(C(=O)C3CC3)CC2)cc1-n1cccc1 +N#Cc1cc(F)cc(C2NCCc3c(F)cc(F)cc32)c1 +CCCC(=O)Nc1cccc(NCC(=O)N2CCCCC2)c1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cnccn1 +OCc1ccc(-c2cn(Cc3csc4c3CCCC4)nn2)o1 +CC(C)c1cc(C(=O)NCc2cccnc2)nc(N2CCOCC2)n1 +CCCn1cc(NC(=O)c2ccc(CC)o2)ccc1=O +O=C(NCC#CCOc1cccc2cccnc12)c1ccc(=O)[nH]c1 +COc1ccc(NC(=O)NCc2cc(Cl)ccn2)cc1C +CC(C)(C)Sc1cc(CNC(=O)N2CCCC2)ccn1 +Cc1c(C(=O)N2CCC(c3ccncc3)CC2)oc2ccccc12 +CC(C)CN1CC(C(=O)NCc2nncn2-c2ccccc2)CC1=O +C=CCNC(=O)N1CCC(c2noc(C)n2)CC1 +CCC(C)C(=O)CSc1nc2sccc2c(=O)n1C +NC(=O)c1ccn(-c2ccccc2NC(=O)CC2CCCCC2)n1 +O=C(CCC1CCCO1)Nc1ccc(Cl)c(Cl)c1 +N#Cc1ccc(NC(=O)N2CCCC2c2ccc3c(c2)OCO3)cc1 +CCN(CC)S(=O)(=O)NC(C)c1ccccc1OC +CN1Cc2nc3ccc(Br)cc3cc2C1=O +COc1ccc(C(=O)Nc2cc(F)cc(F)c2)cc1OC +Cc1cc(C)c(C(=O)N2CCC(CC(N)=O)CC2)c(C)c1 +COc1cc[nH]c(=NS(=O)(=O)c2cccc(Cl)c2C)c1 +CC(C)(O)C#Cc1ccc(C(=O)N2CCN(c3ccccn3)CC2)cc1 +CCOC(=O)C1=C(CN2CCCC2c2cccc(F)c2)NC(=O)NC1 +COc1ccccc1CC(=O)N1CCC(NC(=O)N(C)C(C)C)CC1 +Nc1cc(Br)cnc1NCc1ccccc1 +COc1cccc2c1ccn2CC(=O)N1CCOCC1 +CN(Cc1nccn1C(F)F)C(=O)NCC1Cc2ccccc2O1 +COCc1cccc(C(=O)N2CC(C)CC(C)C2)c1 +CC(C)c1ccc(OC(=O)C23CCC(C)(C(=O)O2)C3(C)C)cc1 +CCC1CN(C(C)C(=O)OCCOC)c2ccccc2N1 +Cc1c(NCc2ccc(F)c(F)c2)cccc1C(N)=O +Cc1ccc(NC(=O)C2CCCN2C(N)=O)cc1Cl +Cc1nc(Sc2nnnn2C(C)C)c2c(CC(C)C)csc2n1 +CNc1ncc(S(=O)(=O)NC2CCCCCC2)cc1C +Cc1nc(NCC2CCCO2)c2cc(C)sc2n1 +COCC(=O)N1CCCC(c2nc3ccccn3c2NC(C)(C)C)C1 +N#Cc1ccc(S(=O)(=O)N2CCN(Cc3ccccn3)CC2)cc1 +CC(Oc1cccc(F)c1)C(=O)N(C)CCC#N +Oc1ccc(-n2nnnc2SCC2CCCC2)cc1 +CCN(CC)C(=O)COc1ccc(C#N)cc1F +CCCN(Cc1ccc(F)cc1)C(=O)c1cnccn1 +CN(C(=O)c1cc(-c2ccncc2)on1)C(CO)C(C)(C)C +CCS(=O)(=O)N1CC(OCc2cccnc2)C2OCCCC21 +COC(=O)c1cc(CN(C)C(c2ccccc2)C(F)(F)F)c[nH]1 +Cc1nc(C2CCCN2C(=O)C2CCC(n3cccc3)CC2)no1 +Cc1ncc(Br)c(Cc2cscn2)n1 +CC(O)CN(Cc1ccccc1)C(=O)Nc1ccccc1F +Cc1ccc(OCC(=O)Nc2cc(-n3cnnn3)ccc2F)c(C)c1 +Cn1ccc(NC(C(=O)N2CCCCC2)c2ccccc2)n1 +O=C(CCn1ncc(=O)c2ccccc21)NC1CCC(O)CC1 +COc1ccc(-c2nc3c(C#N)cccn3n2)cc1OC +CC(C)NC(=O)c1ccc(NC(=O)c2ccccc2Cl)cc1 +O=S(=O)(c1cccc2cnccc12)N1CCOCC1 +CN(Cc1ccccc1)C(=O)COc1cccc(N)c1 +O=C(Nc1ccccc1F)c1c[nH]c2ccccc12 +O=C(Nc1cc(-c2ccoc2)nn1-c1ccccc1)C1CCC1 +Cn1nc(C(C)(C)C)nc1-c1ccc(Cl)c(N)c1 +CNC(=O)c1cccc(NC(=O)c2cccc(COC)c2)c1 +COc1ccc(OC(C)C)c(NC(=O)N(C)Cc2ccncc2)c1 +CNC(=O)c1cnc(C=Cc2cccc(OCCCC#N)c2)s1 +Cc1cc(C)n(-c2nc3c(c(=O)n2CC(=O)NC(C)C)CCC3)n1 +COc1ccc(C(=O)Nc2ccccc2OC)c(OC)c1 +CCNC(=O)c1cccc(NC(=O)c2ccc(Br)cc2)c1 +COCCN1C(=O)CC2C1CCN2C(=O)c1ccccc1F +CC(C)c1ccc(C#N)c(=O)n1C(C)C(=O)Nc1ccccc1 +Cc1oc(S(N)(=O)=O)cc1C(=O)Nc1ccc2c(c1)C(=O)CCC2 +CC(C)(O)CN1CCN(C(=O)c2cccn2Cc2cccnc2)CC1 +CNS(=O)(=O)c1ccc2c(c1)CC(C)N2C(C)=O +Cc1ccc(C(=O)CNC(=O)Cc2ccccc2)cc1 +CC(NCc1nnnn1C(C)C)c1nc(-c2ccccc2)cs1 +CC(Oc1ccc(Cl)cc1)C(=O)N1CCNCC1 +N#CC(NC(=O)c1ccccc1Cl)c1ccco1 +CC(Sc1ncn[nH]1)C(=O)N(C)c1ccccc1 +CC(=O)Nc1cccc(NC(=O)COc2cccc(C)c2)c1 +C=CCN1CC(c2nc3ccccc3n2C)CC1=O +CC(=O)c1cccc(NC(=O)COc2c(C)cccc2C)c1 +CCCCC(=O)Nc1ccc(NC(=O)c2cccc(OC)c2)nc1 +Cn1cc(C(N)=O)cc1C(=O)Nc1cccc(NC(=O)C2CC2)c1 +COc1ccc(F)cc1NC(=O)NCc1ccc2c(c1)OCCCO2 +COC(=O)CN(Cc1cncs1)C1CCCC1 +COc1cccc(NC(=O)NCC(=O)Nc2ccc(Cl)cc2)c1 +CCn1nc(C)c(S(=O)(=O)Nc2cccc(Cl)c2C)c1C +COCc1cccc(CNC(=O)N2CC3CCC2C3)c1 +COc1ccccc1CCNC(=O)c1cnn2c1OCCC2 +CCOC(=O)c1cnn(-c2nc3c(F)cccc3s2)c1N +Cc1c(Br)cccc1CNc1ccc2c(c1)C(=O)NC2 +CCNC(=O)NCCCOC(=O)c1ccc2c(c1)CCN2C(C)=O +CCn1nc(C(=O)NCc2cc(C(C)C)no2)ccc1=O +CCCn1c(C)nnc1SCc1nnc(CC)o1 +OCc1cc2ccccc2nc1-c1ccc2c(c1)OCCO2 +COCC(=O)NC1CCSc2ccc(F)cc21 +Cc1cc(C(=O)N2CCN(C(=O)Cc3ccc(C)s3)CC2)c(C)o1 +O=S(=O)(NCC1COc2ccccc2C1)N1CCCCCC1 +CCOc1ccccc1C(=O)CN(C)C(C)CC#N +CC(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccccc1F +CCN1CC(C(=O)N2CCNC(=O)CC2)CC1=O +Cc1ccc(NC(=O)c2ccc(Cl)cc2N)nc1 +COC(=O)N1CCC(NC(=O)C2CCOCC2)CC1 +CN1CCCC2(CCN(C(=O)CCc3c[nH]c4ccccc34)C2)C1=O +COC(=O)c1ccc(C(=O)NCc2ccccc2OC)cn1 +COc1ccccc1C(NC(=O)NC(C)c1cnn(C)c1)C(C)(C)C +CCCC1(CNC(=O)NCC(C)(C)c2ccncc2)CC1 +COc1ccccc1CCNC(=O)C1CN(C(=O)c2cc(C)on2)C1 +COc1cccc(-c2cn(C)c3c(=O)n(CC#N)cnc23)c1 +COCCNS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CC(=O)c1ccc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)cc1 +CC(=O)c1cc(C#N)c(SCC2CCCO2)nc1C +CCCCn1nc(-c2ccccc2)cc(CO)c1=O +Cc1ncsc1C(=O)N1CCCC1c1c(C)nn(C)c1C +CC(C)(C)c1ccc(C2CCCN2S(C)(=O)=O)cc1 +CC(C)(C)c1nc2c3cc[nH]c(=O)c3c3cc(F)ccc3c2[nH]1 +CC1CN(C(=O)C2CCC(=O)N2Cc2cccs2)CC(C)O1 +Cc1cc(=O)c(OCC(=O)Nc2ccccn2)cn1C +CCN(CC)C(=O)COc1cccc(NC(=O)c2csnn2)c1 +COc1ccc2cc(S(=O)(=O)N3CCC(C(N)=O)CC3)ccc2c1 +CN(C)C(=O)C(OC(=O)c1cn(C)c2ccccc12)c1ccccc1 +CCn1c(C)cc(C(=O)NCc2ccnn2C)c1C +N#Cc1ccc(C(=O)NC(c2ccc(F)cc2)C(F)(F)F)nc1 +Cc1ccccc1SCC(=O)N(Cc1ccco1)CC1CCCO1 +COCc1nc2ccccc2n1CC(=O)Nc1cccc(OC)c1 +Cc1cc(C(=O)Nc2ccc(OCC3CCOCC3)cc2)on1 +CN(CC(=O)NC1CC1)C(=O)CNc1ccccc1C(F)(F)F +COc1ccc(CNC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +OCC(CO)C1c2cccc3ccc4cccc1c4c23 +CC(=O)c1nnc2c(-c3ccc(Br)cc3)c(C)nn2c1C +Nc1ccc2[nH]c(Cc3ccc(Cl)cc3)nc2c1 +CCC(C)C(NC(=O)Cc1c(F)cccc1Cl)C(N)=O +Cc1nc(CNC(=O)COc2ccc3c(c2)CCC(=O)N3)c(C)s1 +CCc1noc(C)c1C(=O)NC1C2CC3CC(C2)CC1C3 +Cc1ccc(NC2=Nn3c(nnc3-c3cccnc3)SC2)cc1 +Cc1ccc(N)cc1NC(=O)CN(C)c1ccccc1 +COCc1nc(C(=O)N2CCN(c3nccc(OC)n3)CC2)cs1 +COc1ccc(C(=O)c2ccc(O)cc2)c(OC)c1 +COC(=O)C1CCN(C(=O)C2CCCO2)c2ccccc21 +CC(=O)c1c(-c2ccc(F)c(F)c2)cnn(C)c1=O +CC(C)N1CC(C(=O)NCc2cccnc2-n2cncn2)CC1=O +Cc1noc(C)c1CCC(=O)N1CCN(c2ccccc2Cl)CC1 +CCCC(CCC)C(=O)N1CC(c2nc(-c3ccncc3)no2)C1 +CC(=O)Nc1cc(F)c(F)cc1NC(=O)c1ccc(F)nc1 +Cc1ccc(NC(=O)c2cc(S(N)(=O)=O)c(C)o2)c(Cl)c1 +CCN(C(=O)Cn1c(-c2ccc(OC)c(OC)c2)noc1=O)C1CC1 +COc1ccccc1C(CNS(=O)(=O)c1ccccc1F)OC +O=c1[nH]c2ccccc2c(-c2ccccc2)c1-n1ccnc1 +CC1CCCN(C(=O)C2CCN(c3cnc4ccccc4n3)CC2)C1 +O=C(COc1ccccc1F)NCc1ccc(Cl)cc1 +CCOc1cc(S(=O)(=O)N2CC(C)OC(C)C2)ccc1Cl +O=C(NCC(O)c1cccc(OC(F)F)c1)c1cc[nH]c(=O)c1 +Cc1ncsc1C(=O)N1CCN(C(=O)c2ccccc2F)CC1 +CCOC(=O)c1cnn(-c2ccc3nncn3n2)c1N +Cc1nc(C2C=CCN2)n(-c2ccc(Cl)cc2C)n1 +COc1ccc(C)cc1NC(=O)NCC1CN2CCCCC2CO1 +CCCCNC(=O)c1ccc(C)c(N(C)S(C)(=O)=O)c1 +Cc1cc(F)ccc1NC(=O)NCc1ccc(C(=O)N(C)C)cc1 +Cc1ccc(-c2nnc(CCC(=O)N(C)CC(N)=O)o2)cc1 +O=C(Nc1ccc2nc(C3CCCO3)[nH]c2c1)c1ccccc1F +O=c1cc(N2CCC(C(O)c3ccccc3)CC2)nc2ccccn12 +COc1ccc(OC)c(NC(=O)c2ccc(OC(F)F)cc2)c1 +CC(Cn1cncn1)NC(=O)c1coc(COc2ccc(F)cc2)n1 +Cc1nc(CCc2ccc3c(c2)OCCO3)sc1CCO +O=C(NCc1cc2ccccc2o1)c1c[nH]c2cccc(F)c12 +COc1ccc(-c2nnc(NC(=O)C(C)(C)C)s2)cc1OC +CC(NC(=O)c1scnc1C1CC1)C(=O)N1CCc2ccccc21 +Cc1nnc(C(=O)N(C)CC2(c3ccccc3)CC2(C)C)o1 +CC(C)CC(=O)N1CC(S(=O)(=O)c2ccc(Cl)cc2)C1 +CC(=O)N1CCC(NC(=O)COc2ccc(Cl)c(C)c2)CC1 +Cc1noc(C2CCN(C(=O)c3cncnc3C(C)C)CC2)n1 +COc1c(COC(=O)c2ccccc2C)cnc(CO)c1C +COCCN(CC(C)C)C(=O)c1cc(F)c(F)cc1Cl +O=C(CN1CCCC2(C1)OCCO2)NCCCC1CCCCC1 +CCCc1cc(C(=O)N2CCN(C(=O)N(C)C)CC2)[nH]n1 +CNC(=O)c1ccc(Cl)c(NC(=O)NCc2cccs2)c1 +CS(=O)(=O)Nc1ccc(C(=O)NCCCO)cc1 +CCCS(=O)(=O)N1CC2CN(Cc3cccc(C)n3)C(=O)C2C1 +CCOc1cc2c(cc1OC)CCNC2C1CC(=O)C1 +O=C(Cc1cnc(-n2cccc2)s1)NCc1ccc2c(c1)OCO2 +CCOc1ccc(CCC(=O)N2CCC(=O)CC2)cc1 +Cc1nc2scc(-c3cccs3)n2c1CC#N +CC(NC(=O)Cn1nnc(-c2ccc(F)cc2)n1)c1ccccc1 +Cc1ccc(Oc2ccccc2)c(NC(=O)NCCc2nc[nH]n2)c1 +COc1c(Cl)c2c(c(OC)c1OC)C1(CC1)CNC2 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(=O)[nH]n1 +Cc1nnnn1-c1cccc(NC(=O)Cn2ccccc2=O)c1 +Cc1cc(NC(=O)C(C)N2CCc3c(nc(C(C)C)n3C)C2)on1 +CC1(C(=O)NCc2cccc3cccnc23)CC1(Cl)Cl +Cc1csc(C(C#N)C(=O)Cc2csc(-c3cccs3)n2)n1 +Cc1ccccc1CCNS(=O)(=O)N1CCCC(C)C1 +Cc1cccc(-n2nc(C(=O)NC(C)C)nc2-c2ccccc2)c1 +CC(Sc1ccccn1)C(=O)NCC(C)c1ccsc1 +O=C(Nc1ccccc1)Nc1cccc(CNC(=O)C2CCOC2)c1 +CC(Sc1nccn1C)c1ccccc1Cl +CC(C)(C)c1ccccc1NC(=O)NCc1ccncc1 +O=C(CSc1ccc(F)cc1)N1CCCCC1CO +O=C(Nc1cccc(C#Cc2ccccn2)c1)c1ccoc1 +Cc1cccc(N(CCC(N)=O)C(=O)c2scnc2C2CC2)c1 +Cc1n[nH]cc1NC(=O)COc1ccccc1C#N +CC(C)NC(=O)CSc1ccc(-c2cccs2)nn1 +CCN(CC)C(=O)c1ccc(Br)c(OC)c1 +CCCNC(=O)c1cc2c(C)nn(-c3ccccc3)c2s1 +COc1ccccc1NC(=O)c1nccc2ccc(N)cc12 +COc1ccc(Cc2cnn(-c3ccccc3)c2N)cc1 +O=C(Nc1ccc(F)cc1NC1CC1)c1cc2ccccc2c(=O)[nH]1 +COc1ccc(NC(=O)c2cn(C)nc2-c2cccs2)c(Cl)c1 +O=C(NCc1coc(-c2cccs2)n1)c1ccccc1F +COc1cc(C(N)=O)ccc1Oc1ccc(N)cc1Cl +CNC(=O)COc1ccc(NC(=O)c2sc(C)cc2OC)cc1 +Cc1nc(C2CCCN2Cc2noc(CC(C)C)n2)no1 +COc1cccc(N2CC(C(=O)Nc3cnoc3)CC2=O)c1 +COc1ccc(CNC(C#N)CC(C)C)cc1OC +C=CCNC(=O)Cc1cc(-c2ccc3c(c2)CC(C)O3)on1 +CC1CN(C(=O)c2sccc2C#N)c2ccccc2S1 +CNC(=O)COc1ccc(-c2ccc(C#N)cc2)cc1 +Cc1ncc(CN(C)C(=O)c2[nH]c3ccccc3c2Cl)s1 +CN(C)C(=O)CCCC(=O)Nc1ccccc1Cc1ccccc1 +O=C(Nc1ccc2[nH]ncc2c1)NC1CCCCC1 +N#CC1(NC(=O)CSc2nnc(-c3cccs3)o2)CCCCC1 +Cc1c(-c2ccc3c(c2)OCCO3)[nH]c(=O)c(C#N)c1C +Cc1cccc(OC(=O)CCNC(=O)c2ccc(F)cc2F)c1 +Cc1ccc(OCC(=O)N(C)C(C#N)c2ccccc2F)cc1 +COCc1ccc(CNS(=O)(=O)N(C)C2CCCCC2)cc1 +COc1ccccc1CNC(=O)Nc1cccc(F)c1 +CCOCCCNC(=O)c1cc2cnn(CC)c2nc1N +COc1c2ccc(C(=O)NCc3ccc(C)cc3)cc2nn1C +NC(=O)CCOc1ccc(NC(=O)c2ccc(O)c(Cl)c2)cc1 +O=C(CN1CCOCC1)NCc1ccc(-c2ccc(Cl)cc2)o1 +OCc1cc(CC2(NCc3ccc(C(F)(F)F)cc3)COC2)no1 +CC(CO)NC(=O)c1cc2c(s1)CCCCC2 +O=C(CNC(=O)c1ccsc1)N=c1[nH]ccn1Cc1ccccc1 +COc1ccc(CC(=O)NCCc2ccc3c(c2)OCO3)cc1 +CCc1nc(CNC(=O)NCC(C)(C)NS(C)(=O)=O)cs1 +CCCn1c(=O)c2c(nc3n(CCO)c(C)c(C)n23)n(C)c1=O +Cc1nn(Cc2ccccc2Cl)c(=O)c(C#N)c1C +CCCNC(=O)CN1C(=O)CCc2cc(N)ccc21 +CCOc1nn(CC)cc1C(=O)Nc1nnc(SCC)s1 +O=C(CCCOc1ccccc1)N1CCN(C(=O)c2ccco2)CC1 +COc1cccc(CN2CCOCS2(=O)=O)c1OC +CCOC(C)c1noc(Cn2ccc(-c3ccc(F)cc3)n2)n1 +CN(C)C(=O)c1cnccc1C(=O)Nc1ccccc1 +O=C(NCCCCO)c1ccc(C(F)(F)F)cc1 +COCCOc1cc(C)ccc1NC(=O)Cc1ccon1 +Cc1cc(C(=O)NC2CCCC(C(F)(F)F)C2)c2c(C)noc2n1 +CCC(C)N(C(=O)C1CN(C(C)=O)C1)C(C)CC +COC(=O)CC1C(=O)NCCN1S(=O)(=O)c1ccc(F)cc1 +Cc1ccc(OC(C)C(=O)Nc2cccnc2)cc1 +CCCCc1nc(CS(=O)(=O)c2ccc(Cl)cc2)no1 +CCNC(=O)NC1(C(=O)Nc2ccc3oc(=O)ccc3c2)CCCC1 +COC(=O)N1CCCC(NC(=O)N2CCCC2)C1 +Cn1cc(C(=O)N2CC(c3nc(-c4ncccn4)no3)C2)nn1 +O=C(NC(C(=O)NCC(F)(F)F)c1ccccc1)c1cccs1 +CC(C)(C(=O)Nc1nnc(-c2ccccn2)s1)c1ccccc1F +Cc1cc(N)ccc1NC(=O)CN1CCc2ccccc21 +Cn1ccc2cc(C(=O)Nc3ccccc3F)ccc21 +COc1ccc(Br)c2c(=O)c3c([nH]c12)CCC3 +CCC(C)C(=O)NCC(C)c1nc2ccccc2s1 +COc1ccc2c3c(ccc2c1)C1CCC(=O)N1CC3 +Cc1nnc(-c2ccc(NC(=O)c3scnc3C3CC3)cc2)o1 +COc1cccc(-c2cc(NCc3cccnc3)nc3[nH]ccc23)n1 +COc1ccc(CC(=O)N2Cc3cncnc3C2)cc1OC +CN1CC(C(=O)NCC2(N3CCOCC3)CCCCC2)CC1=O +Cc1cccc(Cn2cccc(C(=O)OCc3nccs3)c2=O)c1 +CS(=O)(=O)N1CCCC(C(=O)N2CCOCC2C2CC2)C1 +Cc1nc(CNC(=O)Nc2cc(-c3ccco3)ccc2F)c(C)s1 +CCCCN(C)C(=O)CCC(=O)c1ccc(Cl)c(N)c1 +C=CCC(CC=C)C(=O)N1CCC(C(N)=O)c2ccccc21 +COc1cccc(CC(=O)N2CCCC(CS(N)(=O)=O)C2)c1 +C=CCCOC(=O)c1nnn(-c2ccc3ncccc3c2)c1C +O=C(CCSc1ccccn1)NCC1CCN(c2ccccc2)C1 +Cc1ccc(C)c(OCCCN2CCn3c(nn(C)c3=O)C2)c1 +CCSc1ccc(Cl)cc1NC(=O)Cc1ccc[nH]1 +COCc1ccc(C(=O)N2CCCC2c2ccccc2)o1 +COc1cccc(-c2ccnc3nc(-c4cccnc4)nn23)c1 +O=C(NCc1ccccc1)c1c(F)cccc1C(F)(F)F +CCOC(=O)C1CCCC(=O)N1c1ccc(F)cc1F +CCC(=O)N1CCc2c(C(=O)NCc3ccco3)cccc21 +Cc1ccc(Cl)cc1S(=O)(=O)Nc1cccnc1 +O=C(NCC1CCC1)NC1CCOc2c(Cl)cccc21 +CCN(CC(F)(F)F)C(=O)c1ncccc1OC(C)C +COC(=O)C1(NC(=O)c2cc(C)n[nH]2)CCCC1 +COCC(C)NC(=O)c1ccc(C(F)(F)F)cc1 +CCc1cc(CN(C)c2nc(C)nc3ccsc23)on1 +Cc1ccc(CNC(=O)C2(O)CCCC2)c(OCC2CC2)c1 +COc1ccc(CNC(=O)CNC(=O)c2ccc(C)c(C)c2)cc1 +CNC(=O)CCCN1C(=O)C(c2ccccc2)Oc2cccnc21 +CC(=O)c1nc2cc3c(cc2n1C(C)(C)CO)OCCO3 +CC(NC(=O)c1cc(F)ccc1F)c1ccc2c(c1)OCO2 +COC(=O)CCNc1cccc(OC(F)(F)F)c1 +CC1(C)CC(=O)c2sc(NC(=O)Cc3ccc[nH]3)nc2C1 +C=CCN(C(=O)C1CC(=O)N(C(C)C)C1)c1ccccc1 +CCOC(=O)c1ccc(NC(C)c2cc(C)sc2C)nc1 +CCC(C)NC(=O)c1ccc2c(=O)n3c(nc2c1)CCCC3 +C#CCn1c(C2CC(=O)N(c3cccc(F)c3)C2)nc2ccccc21 +C1=CC2CC1CC2CNc1cnn(-c2ncccn2)c1 +Cc1ccc(C2OCCCC2NC(=O)c2cc(C)no2)cc1 +CCc1nnc(-c2cc(S(=O)(=O)NCCOC)c[nH]2)o1 +O=C(NCCCn1cccn1)NC1CCN(c2ccccc2)CC1 +O=C1CCCN1Cc1nnn2c1CN(S(=O)(=O)C1CC1)CCC2 +CCCOc1ccc(Br)cc1S(=O)(=O)NC(C)C +Cc1nc(CNC(=O)c2cnc(C3CCCO3)s2)no1 +COC(=O)c1ccc(N2CCN(CCC#N)C(C)C2)cc1 +CSc1ccc(OCc2nc(CC(C)C)no2)cc1 +Cn1cc(Cl)cc1C(=O)Nc1c2c(nn1C)CCC2 +CCCc1cc(=O)[nH]c(SCC(=O)NC2(C#N)CCCCC2)n1 +CC(C(=O)N1CCCCCC1)N1CCN(C(=O)c2ccco2)CC1 +CC(C)COCCNS(=O)(=O)c1ccccc1 +O=C(CSc1nccc(=O)[nH]1)Nc1cccc2ccccc12 +COC(=O)C(C)NC(=O)C1CNCc2cccc(C)c21 +CCC(C)NC(=O)NCc1nc(C(=O)N2CCCC2)c(C)o1 +CC(C)(C)C(=O)CNC(=O)Cn1ccc2ccccc21 +CN(CCC#N)S(=O)(=O)N1CCCC(CN2CCOCC2)C1 +CSc1cccc(NC(=O)c2csc(C)n2)c1 +Cc1n[nH]c(C)c1CC(=O)NCCCN1CCOCC1 +Cc1cccc(C)c1OCC(=O)Nc1cccc(N2CCCC2=O)c1 +O=C(c1ccc[nH]1)N1CCOCC2(CCC(CN3CCOCC3)O2)C1 +CC(C)C(NC(=O)c1cc2cc(F)ccc2[nH]1)c1cccs1 +O=C(Nc1cnn(Cc2ccccn2)c1)c1ccc[nH]c1=O +CCc1cnc(C(C)NC(=O)NCc2ncn(C)n2)s1 +CCN(CC)C(=O)c1cncc(C(=O)N(CC)CC)c1 +COc1ccc(-c2ccc(-c3nc(CC(C)C)no3)cn2)c(OC)n1 +CCc1nc(CC(=O)OCc2nnc(-c3ccccc3)n2C)cs1 +Cc1c(C(=O)Nc2ccc(Cn3cccn3)cc2)[nH]c2c1C(=O)CCC2 +CC(=O)Nc1ccc2nc(NC(=O)C3(C#N)CCCC3)sc2c1 +CCc1ncc2c(n1)CN(Cc1cc(=O)n(C)c(=O)n1C)CC2 +COc1cc(C(C#N)OC(C)=O)cc(OC)c1OC +Cc1cccc(NC(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)n1 +COc1ccc(C(C)COC(=O)c2sccc2-n2cnnn2)cc1 +COCCc1ccc(OS(=O)(=O)c2cccc(F)c2)cc1 +O=S(=O)(Nc1ccccc1F)c1ccc2c(c1)CNCC2 +Cc1cc(=O)c(O)c(CN2CCOCC2)n1C(C)(C)CO +O=C(c1ccc(S(=O)(=O)C2CCCC2)cc1)N1CCCCCC1 +COc1ncc(-c2nccn2Cc2nc3cc(C)c(C)cc3[nH]2)cn1 +O=C(NCCNC(=O)C1CC1c1ccc(F)cc1)c1ccc(F)cc1 +N#CC1(CN2CCN(c3cccc(Cl)c3)CC2)CC1 +CC(OC(=O)c1cc(F)cc(F)c1)C(=O)N1CCc2ccccc2C1 +CC(=O)Nc1nc2ccc(C(=O)NCC(C)C)cc2s1 +CC(O)CC(C)CNC(=O)C1CC1c1ccc(Cl)cc1 +OCCNc1ncnc2ccc(-n3ccnc3-c3ccccn3)cc12 +Cc1cc(C)n(CCCNC(=O)CCc2cnn(C)c2C)n1 +CCN(CC)C(=O)c1snc(-c2cccc(Cl)c2)c1N +Cc1nc2ccc(NC(=O)CSc3nncn3C(C)C)cc2o1 +CN1CC(C(=O)NC(c2ccccc2)c2ccc3nc[nH]c3c2)CC1=O +N#Cc1cccc(NC(=O)C2CC(=O)N(C3CCOCC3)C2)c1 +CC(C)(C)CCC(=O)NCc1ccc(-n2cncn2)cc1 +CCOC(=O)c1c(NC(=O)CO)sc(C(C)=O)c1C +O=C(Cc1nc(-c2cccnc2)n[nH]1)NCc1cc(F)cc(F)c1 +CNC(=O)CSc1nc(-c2ccco2)nc(C)c1C(C)=O +Cc1ccc(Cc2nc(C(=O)OCc3nc(C)no3)cs2)cc1 +CCC(Nc1ccc2nnnn2n1)c1ccc2c(c1)CC(C)(C)O2 +Cc1ccoc1C(=O)N1CCC(c2ccnc(-c3ccncc3)c2)C1 +CC(C)C1C(=O)N(C)CCN1C(=O)CCNC(=O)c1ccccc1F +Cc1ccc(NC(=O)CSc2nnc(NC3CC3)s2)c(C)c1 +CCCc1nc(CS(=O)c2n[nH]c(CC)n2)cs1 +COC(=O)CN(C(=O)c1ccc(Cl)c(OC)c1)C(C)C +NS(=O)(=O)c1ccc2c(c1)N(CC(=O)NC1CC1)CC2 +COc1ccc(N2CC(C(=O)NCc3ccccc3C)CC2=O)cc1 +O=C(NC1CC1)c1nnsc1-c1ccc(Cl)cc1 +COCCOC1CC2CN(c3cc(OC)ncn3)CCN2C1 +COc1ccc(C(O)CSc2nc(C)cc(C)c2C#N)cc1F +Nc1ncn(CC(=O)N2CCC3CCCCC3C2)n1 +COCc1ccccc1CNS(=O)(=O)c1ccc2c(c1)CCCC2 +Cc1cccc(C(=O)Oc2ccc(Oc3ccccn3)cc2)n1 +Cc1cc(Br)c(O)c(C(=O)NCCS(N)(=O)=O)c1 +CCCN(CCC)C(=O)c1cncc(Br)c1 +Cc1ccc(OCCCOc2c(C)occc2=O)cc1 +CC1CCC(C(N)=O)CN1c1ncnc2cc(F)c(F)cc12 +O=C(Cn1nnc(-c2ccccc2Cl)n1)NC1CC1 +CCn1nc(C)cc1C(=O)NCC(=O)NCc1ccc2c(c1)OCO2 +Cc1cc(NC(=O)C(C)S(=O)c2nncn2C(C)C)on1 +O=C(c1cc[nH]n1)N1CCCn2cnc(COCC3CC3)c2C1 +Cc1nc(-c2ccc(C)n2C)sc1C(=O)NC1CC1 +CN(CC(N)=O)C(=O)COc1cccc(C(N)=O)c1 +CC(C)C(=O)Nc1cccc(OCC(=O)Nc2ccc(O)cc2)c1 +CCC(CC)NC(=O)NCc1noc(-c2ccsc2)n1 +CC(NC(=O)c1ccc(N2CCCC2)nn1)c1nc2ccccc2[nH]1 +O=C(CN1CCN(c2ccccc2)CC1)c1ccccc1 +CCCC1CN(S(C)(=O)=O)CC1NC(=O)c1cnc(C)nc1 +C=CCN1CCC2(CCCN(S(=O)(=O)c3cccs3)C2)C1=O +CC1(C)Cc2cccc(OCC(=O)Nc3nnc(C4CC4)s3)c2O1 +CC(C)NC(=O)c1nsc(C(=O)NCc2ccccc2F)c1N +COc1ccc(Cc2nc(-c3ccc4nncn4c3)no2)c(Cl)c1 +O=C(NCCc1cn2ccccc2n1)c1cc2c(cc1O)OCO2 +CCC(C(=O)N1CCOCC1)n1c2ccccc2c2cn[nH]c(=O)c21 +CCCc1noc(CSc2nnc(C3CC3)s2)n1 +O=C(CCc1cccc(F)c1)OCC1CC(=O)N(C2CC2)C1 +Cn1cnnc1SCc1nc(-c2ccsc2)no1 +CCC(=O)NC1CCCN(C(=O)Nc2cccc(OC)c2)C1 +CC(C)(C)NC(=O)CNC(=O)Nn1cnc2ccccc21 +O=C(c1ccc2occc2c1)N1CC=C(c2ccccc2)CC1 +O=c1cc(CO)[nH]cc1OCc1ccc(Br)cc1 +OCC1(O)CCN(c2cccc(C(F)(F)F)n2)CC1 +Cn1nccc1-c1cccc(-c2noc(CNC(=O)c3ccco3)n2)c1 +Cc1ccc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)s1 +CCOC(=O)CSc1nnc(-c2ccco2)n1-c1ccc(F)cc1 +O=C(Cc1c(F)cccc1F)NC1CC(=O)N(C2CC2)C1 +CCc1cc(=O)[nH]c(Cn2nc(C(F)(F)F)ccc2=O)n1 +Cc1ccc(NC(=O)c2cccnc2)cc1S(C)(=O)=O +CC(=O)NCC(=O)N1CCCCCC1C=Cc1ccccc1 +O=C(Nc1ccc(F)cc1OCC1CC1)c1ccco1 +CC(Sc1nnnn1C)C(=O)NCCC1=CCCCC1 +Cn1ncc2c(N3CCCC3Cc3ccccc3Cl)ncnc21 +CCN(Cc1ccc(OC)cc1)S(=O)(=O)c1cccc(C#N)c1 +O=C(NC(Cc1ccccc1)C(=O)N1CCCC1)C1CCCC1 +COc1ccccc1CNC(=O)COC(=O)c1cccnc1 +CC(Sc1nnnn1C1CC1)c1nc2ccccc2s1 +Cc1ccc(S(N)(=O)=O)cc1C(=O)N1CCOC2CCCCC21 +CC(C)OC(=O)Cn1c(C2CC2)nc2ccccc21 +Cn1cc(C(=O)NCc2ccc(S(N)(=O)=O)cc2)nn1 +COC(=O)C(C)NC(=O)CNS(=O)(=O)c1ccc(F)cc1 +CCOC(=O)c1ccc(Nc2ncnc3c2nnn3CC)cc1 +Cc1ccn2c(=NC(=O)Cc3ccc(C)s3)[nH]nc2c1 +Cc1c(C(=O)NCCc2cccs2)nc2cc(Cl)ccn12 +CNC(=O)c1ccc(CNCc2nnc3n2CCCCC3)cc1 +CC1(C)CC(C(=O)N2CCC3(CC2)C(=O)Nc2ccccc23)CCO1 +CCC(C)OC(=O)c1ccc(N2CCOC2=O)cc1 +Cc1nc(C)c(C(=O)N2CCOC(C(=O)NC3CCCC3)C2)s1 +CC(C)(C)c1ccc(C(=O)N2CCN(Cc3ccsc3)CC2)cc1 +Cc1cc2oc(=O)cc(Cn3nnnc3C3CCCC3)c2cc1C +O=C(c1cccnc1)N1CCC2(CCC(C(=O)N3CCCC3)O2)CC1 +Cn1cc(-c2ncc(C(=O)NCCOc3cccnc3)s2)cn1 +O=C(NCCOCCO)c1ccc(Br)cc1 +COc1cccc(OCCN2CC(CO)CC2=O)c1 +COC(=O)c1ccc(NC(=O)CSc2nnc3n(N)cnn23)cc1 +Cc1ccnc2nc(C(=O)Nc3ccc(OC(C)C)c(Cl)c3)nn12 +N#Cc1ccc(NC(=O)CCn2ncc3ccc(Cl)cc32)cc1 +O=C(NC1CC1)c1cccc(OC(=O)C2CC3CCC2O3)c1 +Cc1ccnc(OCC23COCC2CN(C(=O)c2cnn(C)c2)C3)n1 +CN(C)c1ncc2c(n1)CN(C(=O)CNC(=O)C1CCC1)CC2 +CCc1cc(NC(=O)C(C)Oc2cccc(C(C)=O)c2)[nH]n1 +Brc1csc(COCC2CCOCC2)c1 +Nc1cc2c(c(Cc3cc(N)cc4c3OCOC4)c1)OCOC2 +Cc1ccc(CC(=O)N2CCN(Cc3cccs3)CC2)cn1 +O=C(NCCc1nnc2n1CCC2)c1ccccc1OC1CCCC1 +N#CC1(C(=O)Nc2nc(CN3CCOCC3)cs2)CCCCC1 +CN(C(=O)C1CCN(c2ccc(Cl)cc2)C1=O)C1CC1 +COC(=O)c1ncn(Cc2ccc(OCC(F)(F)F)cc2)n1 +NC(=O)CCCNC(=O)Nc1cccc(Cl)c1Cl +N#CC1(NC(=O)c2cnc(-c3ccc4c(c3)OCO4)s2)CCC1 +NC(=O)c1cnc(NCCc2cccs2)c(Cl)c1 +CS(=O)(=O)N1CCc2cc(C(=O)CN)ccc21 +CCc1nnsc1C(=O)N(C)Cc1cnn(C)c1 +CNC(=O)c1ccc(Cn2c(-c3cccnc3)noc2=O)cc1 +CC(=O)N1CCN(C(=O)C(C)Nc2ccc3oc(C)nc3c2)CC1 +COCCCNC(=O)C(C)Nc1ccc(F)c(Cl)c1 +C#CCN1CCN(C(=O)NCCCOC2CCOC2)CC1 +NC(=O)N1CCCC1C(=O)N1CCN(CCc2ccccc2)CC1 +CC(=O)NC(C)C(=O)Nc1ccc2c(C)cc(=O)oc2c1 +CCN(Cc1ccoc1)C(=O)NCc1ccccc1-n1cccn1 +CSc1ccc(S(=O)(=O)NC(C)C)cc1C(=O)N1CCCC1 +CC(=O)c1ccccc1NC(=O)C(C)Oc1ccc(C#N)cc1 +O=C1C(N2CCOCC2)CCCN1Cc1ccccc1C(F)(F)F +COc1ccc(C)cc1NC(=O)Nc1c(C)nc2sccn2c1=O +Cc1ccc(-c2cc(C(=O)NCCN3CCCCCC3=O)n[nH]2)s1 +CC(NCC(F)(F)F)(C(N)=O)c1cccc(C(F)(F)F)c1 +CN1C(=O)Cc2cc(CC(=O)N3CCC(O)CC3)ccc21 +COc1ccc(CCC(=O)N2c3ccccc3CC2C)cc1 +CC(C)(C)NC(=O)CSc1nc2ccccc2c(=O)n1CCCO +Cc1nc2ccc(N(C)C(=O)c3csc(-c4ccco4)n3)cc2[nH]1 +CC(Cn1ccnc1)NC(=O)c1ccn(C)c(=O)c1 +COc1ccc(S(N)(=O)=O)cc1C(=O)Nc1cc(C)cc(C)c1 +COc1ccccc1OCC(=O)NCCc1ccsc1 +CCOc1ccccc1C(=O)NCc1ccc2[nH]c(=O)[nH]c2c1 +Cc1ccccc1C1CC(=O)CC(Nc2nonc2N)C1 +O=C(NCc1ccc(F)cc1)c1ccc(-c2cccc(F)c2)nc1 +CNS(=O)(=O)c1cccc(CNC(=O)NCC(F)(F)F)c1 +CN(C)C(=O)Cc1ccccc1NC(=O)N1CC(N2CCOCC2)C1 +CCC(C)NC(=O)CC1Sc2ccc(C(F)(F)F)cc2NC1=O +CCN1CC(C(=O)Nc2ccc(Cl)c(Br)c2)CC1=O +COc1cc(=O)n(-c2ccccc2C)nc1C(=O)N1CCC(C)CC1 +CCN(CC(C)C)C(=O)C1CCN(c2ccc(F)c(F)c2)C1=O +CCN(CC)C(=O)Cn1nc2n(CCOC)c3ccccc3n2c1=O +COCc1cccc(C(=O)NCc2ccc(F)cc2C(F)(F)F)c1 +COC(=O)CCC(=O)Nc1ccccc1Cc1ccccc1 +O=C(CCNC(=O)OCC(F)(F)F)NC1CCCc2occc21 +COc1cc(C)c(Cl)c(C)c1S(=O)(=O)NCCO +O=C(Nc1n[nH]c2cccc(F)c12)C1(n2cnnn2)CCCCC1 +Cc1ccc(NC(=O)C(O)c2ccccc2)c(C)c1 +CCOC(=O)c1sc2nc(C(C)N(C)CC)[nH]c(=O)c2c1C +CCOCCNS(=O)(=O)c1c(Cl)cccc1Cl +CCCCCC(C)NC(=O)c1ccc(NC(N)=O)cc1 +CN1CC(C(=O)N2CCN(CCc3ccccc3)CC2)CC1=O +CC(Oc1ccc2ccc(=O)oc2c1)C(=O)N1CCCCCC1 +O=C(CNC(=O)c1ccccc1Cl)Nc1ccc2c(c1)CCC2 +O=C(OCc1c(F)cccc1F)c1ccnc(-n2ccnc2)c1 +O=C(CCN1CCOCC1)c1ccc2c(c1)OCCCO2 +CSc1ncccc1C(=O)Nc1ccc(N(C)C)nc1 +Cc1cc[nH]c(=NS(=O)(=O)c2ccc(F)cc2F)c1 +CCc1cnc(N2CCOC3(CCCN(c4nncs4)C3)C2)nc1 +Cc1nc(C)n(C(C)CNC(=O)c2cccs2)n1 +CN(Cc1ccncc1)C(=O)NCCCN(C)c1ccccc1 +Cc1ccc(-c2c3c(=O)n(C)c(=O)n(C)c3cn2C(C)(C)CO)cc1 +COc1ccc(N2C(=O)CN=C2Nc2nc(C)cc(C)n2)cc1OC +O=c1oc2cc(O)ccc2cc1S(=O)(=O)c1ccc(Cl)cc1 +Cc1occc1C(=O)Nc1ccc(NC(=O)CN2CCOCC2)cc1 +CN(CC(=O)NC(C)(C)C)C(=O)c1ccc(F)cc1Cl +O=C(CCc1nc(-c2ccc3cc[nH]c3c2)no1)Nc1nccs1 +Cc1nc(C(=O)OC(C)C(N)=O)nn1-c1ccc(F)cc1 +Cc1cc(NC(=O)NC2CCSc3ccccc32)no1 +CC(=O)N1CCC(C(=O)Nc2cccc(C)c2C)CC1 +CCC(=O)Nc1cccc(N(CCO)CCO)c1 +Cc1cc(S(=O)(=O)n2ccnc2C)ccc1F +CCN(C)C(=O)c1nn(-c2ccccc2)c(=O)n(CC)c1=O +CC(O)CNC(=O)C1CNCc2cccc(Cl)c21 +O=C(CCc1c[nH]c2ccccc12)NCc1ccc(F)cc1 +COc1ccc2c(c1OC)C(=O)OC2CC(=O)c1ccccc1 +COc1cc(C(=O)NC2CC2)ccc1OC(F)F +Cc1ccc(Nc2nn[nH]c2C(=O)NCc2ccncc2)cc1C +Cc1ccc(N2CC(C)C3(CCN(Cc4cccnc4)C3=O)C2)nn1 +COCCNC(=O)c1cc(=O)c(OCc2ccc(Cl)cc2)co1 +CC(C#N)CCC(=O)Nc1ccc(OC(C)C)cc1 +CCCNc1nc(-c2cccn(C(C)CC)c2=O)cs1 +CCCCCNC1=NS(=O)(=O)c2ccccc2N1C +O=C(Nc1cccc(C(=O)N2CCOCC2)c1)C1CC1(Cl)Cl +COC(=O)Nc1nc2ccccc2n1Cc1ccc(F)cc1 +CC(C)Oc1ccc(CNC(=O)Cn2c(=O)[nH]c3ccccc32)cc1 +O=C(NC1CCCC2OCCC12)N(Cc1ccco1)Cc1ccco1 +Cc1nn(C)c2ncc(NC(=O)COc3ccc(F)cc3)cc12 +CS(=O)(=O)N1CCc2cc(C(=O)N3CCOCC3)ccc21 +CC(c1ccccc1F)n1cc(C(=O)NCC2CCCO2)nn1 +CCOC(C)c1noc(COc2ccc(C#N)cc2C)n1 +O=C(CCC(=O)c1cccs1)OCc1nc2ccccc2o1 +CCc1ccccc1NC(=O)c1c(-c2cccnc2)noc1C +Cn1nccc1-c1nnc(NC(=O)C2COc3ccccc3O2)o1 +COc1ccc2[nH]cc(C3=CCN(C(=O)C(C)NC(C)=O)CC3)c2c1 +CCN(Cc1ccc2c(c1)OCO2)S(C)(=O)=O +O=C(Cc1coc2cc3c(cc12)CCC3)NCC1CCCO1 +CNC(=O)c1ccc(NC(=O)Cn2cc(Cl)cn2)cc1 +CCN(CC1COc2ccccc2O1)C(=O)c1cc2ccccc2o1 +O=C(CN1CCCc2cccc(F)c21)NCc1ccco1 +O=C(CSc1n[nH]c(=O)n1C1CC1)NCc1ccc(Cl)cc1 +CN(Cc1cc2ccccc2[nH]c1=O)C(=O)c1ccccc1F +O=C(C1CN(c2ncccn2)CCO1)N1CCC2(CCCCC2)C1 +OCCn1c(-c2ccccn2)nc2cc3c(cc21)OCCO3 +N#Cc1c(F)c(F)c(Br)c(F)c1F +CC(C)(C)c1ncc2c(n1)CN(C(=O)C1CCCCO1)C2 +Cc1cc(C)cc(C2(C(=O)NCCc3nc(C)cs3)CC2)c1 +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(-n2cnnn2)cc1 +CC(NC(=O)Nc1ccc(OC(F)F)cc1)c1nnc2ccccn12 +CC(C#N)(NC(=O)COc1ccc(Cl)cc1C(N)=O)C1CC1 +Cc1cc(=O)[nH]c(NCC2CCN(C(=O)C(C)C)CC2)n1 +CCc1cc2n[nH]c(=O)n2c(-c2ccc(F)cc2)n1 +COc1cc(OC)cc(C(=O)Nc2nnc(-c3cccc(F)c3)o2)c1 +CCC(=O)Nc1cccc(NCC(=O)N2CCOCC2)c1 +Cc1ccccc1-n1ccnc1SC1CCOC1=O +COC(=O)c1ccc(-c2nc(Cn3ccnc3)cs2)cc1 +COc1ccc(Br)c(C(=O)Nc2ccc(OC)nc2)c1 +COCCN1CCN(C(=O)NC2CCCC(C)C2C)CC1=O +c1ccc2c(-c3nccn3CCn3ccnc3)cccc2c1 +CCOc1ccc(C(C)NC(=O)Nc2cnn(C)c2)cc1 +CCNC(=O)COc1cc(OC)ccc1C(N)=O +CCC(=O)NCC(=O)N1CCC(Nc2ccccc2OC)CC1 +COCC(C)OC(=O)Cc1csc(-c2ccccc2)n1 +C=CCNC(=O)c1nn(-c2ccccc2)c(=O)cc1Cl +Brc1cnc2c(cnn2Cc2ccncc2)c1 +Cc1cc(OCc2nnc(CCO)o2)cc(C)c1Cl +CN(Cc1ccncc1)C(=O)c1ccn(C)c(=O)c1 +CCCC1CN(C(=O)c2ccc(OC3CCCC3)c(OC)c2)CCO1 +CN(C(=O)Cc1ccsc1)c1nc2c(s1)CCc1occc1-2 +COCc1cccc(NC(=O)NCc2ncoc2C)c1 +Cc1csc2ncc(C(=O)NCc3ccc(F)cc3)c(=O)n12 +CCCNC(=O)c1nsc(C(=O)NCC(C)C)c1N +N#Cc1nccnc1NCc1cccc(-n2cccn2)c1 +COc1ccc(C)cc1NC(=O)c1cccc(OC)c1O +CCOC(=O)NCCC(=O)Nc1ccc(C)c(F)c1 +CC(NS(=O)(=O)c1ccc(C#N)cc1)c1cc2ccccc2o1 +COc1ccnc(NC(=O)c2ccc3ccc(Cl)cc3n2)c1 +CC1CN(C(=O)OC(C)(C)C)CCN1CCC(=O)N1CCOCC1 +Cc1ccc(C(O)CNC(=O)Nc2cccc(Cl)c2)o1 +CCOC(=O)Nc1cccc(C(=O)NCc2ccc3c(c2)OCO3)c1 +CSc1cccc(NC(=O)C2CCCN2C(=O)c2cccs2)c1 +N#Cc1cccc(CNC(=O)CSc2ccncc2)c1 +COc1ccc(C2(CNC(=O)Cn3cnnn3)CCCCC2)cc1 +CCC1=C(C(=O)OC)C(c2ccc(C)o2)n2ncnc2N1 +CC1COC2(CCN(c3ncnc4sc5c(c34)CCC5)CC2)O1 +Cc1ccc(NC(=O)NCc2c(C)nn(-c3ccccc3)c2C)cc1 +CC(NS(=O)(=O)c1cn(C)c(=O)n(C)c1=O)c1cccs1 +CC1(C)CNC(=O)c2nc(-c3nc4cc(F)ccc4[nH]3)[nH]c2C1 +CC(=O)Nc1cccc(OC(=O)C2CCCN2C(=O)c2ccco2)c1 +Cc1cccc(NC(=O)c2cc(=O)c(OCc3ccccc3)c[nH]2)n1 +Cc1nccc(NC2CN(C(=O)CN3CCCC3=O)CC2C(C)C)n1 +Cc1ccc(-n2nnnc2SCC(=O)N2CCCC2)cc1 +CN(Cc1ccccc1F)C(=O)COc1ccc(F)c(F)c1 +Cc1ccncc1NC(=O)N1CCCC1C1CCCC1 +Cc1cccc(CN2CCc3onc(CNc4ncccn4)c3C2)n1 +CC(C)C(=O)NCCc1cc(Cl)c2c(c1)OCCO2 +CC(C)Cc1ccc(CC(=O)Nc2nnc3ccccn23)cc1 +CCn1c(CC2CCN(c3cc(NCCO)ncn3)CC2)n[nH]c1=O +CCCOc1ccnc2c1c(=O)n(CCC(C)C)c(=O)n2C +Cc1nn(-c2ccccc2)c(SCc2ccco2)c1N +Cc1ccc(S(=O)(=O)NCCNC(=O)C2CC2)c(Cl)c1 +Cc1onc(-c2ccccc2Cl)c1C(=O)N(C(C)C)C(C)C +CCCn1nc(C)c(CNCc2c(F)c(F)cc(F)c2F)c1C +CCN(C(=O)c1cc(OC)c(OC)cc1OC)c1ccncc1 +COc1cc(C)c(C(=O)Nc2ccccc2C)cc1OC +C#CCN1CCN(C(=O)NCCNC(=O)c2ccc(C)cc2)CC1 +Nc1cccc2c1CCN(CCOc1ccccc1Cl)C2 +Cc1cc(NS(=O)(=O)c2c(C)noc2C)no1 +Cc1nn(C)c(C)c1S(=O)(=O)NCC(=O)Nc1cccc(F)c1 +CCC(C)(C)NC(=O)COc1cc(Cl)ccc1N +Nc1cnc(-c2cc(Br)cs2)nc1 +CNC(=O)CC(C#N)c1ccc(OC)c(C(C)C)c1 +COCCN1CC2(CCN(C(=O)c3ccc(C)nc3)CC2)C1=O +Cc1cc(C(=O)N2CCOc3ccc(F)cc32)c2c(C)noc2n1 +O=c1[nH]nc2c3sc(N4CCCCCC4)nc3ncn12 +CCCN(C)C(=O)c1csc(NC(=O)c2c(F)cccc2F)n1 +CCCS(=O)(=O)N1CCCc2cc(NS(=O)(=O)CC)ccc21 +C=C(C)CN(CC)C(=O)CN1CCOCC1CC(C)C +COCC(C)NC(=O)C(C)NC(=O)c1ccccc1Cl +O=C(CNc1ccc(F)c(F)c1F)Nc1ccc2c(c1)OCO2 +COc1ccc(OC)c(Nc2ncccc2CO)c1 +CNC(=O)CN(c1cccc(Br)c1)S(C)(=O)=O +Cc1ccccc1NC(=O)C1CCN(C(=O)N(C)C)CC1 +O=C(CCC(=O)c1ccc(F)cc1F)Nc1ccc(F)cc1F +Cc1ccc(NC(=O)CN(C)Cc2nc(N)nc(N(C)C)n2)cc1 +CCN(Cc1cccc(NCc2csc(C(C)(C)C)n2)c1)C(C)=O +CCN(CC)C(=O)c1sc(NC(=O)c2cnccn2)c(C#N)c1C +O=C(Cn1ccc(=O)[nH]c1=O)N(Cc1ccccc1)C1CC1 +CCOc1ccc(S(=O)(=O)NCCc2cn3ccccc3n2)cc1 +N#Cc1c(-c2ccccc2OCCO)cc(C2CC2)nc1N +CCC(CC)c1nnc(NC(=O)C(C)(C)C)s1 +O=C(CNc1ccc(C(F)(F)F)cc1)N1CCOCC1 +CC(=O)c1cnc(NCc2cc(C(C)(C)C)n[nH]2)nc1C +CCOc1ccc(C(=O)Nc2ccccc2C(N)=O)cc1OC +CCc1noc(-c2ccc(C)c(NC(=O)Cc3ccc[nH]3)c2)n1 +CC(C)CCNC(=O)CCc1ccc(N2CCCC2)c(N)c1 +COc1cc(C(=O)OCC(F)(F)F)cc(OC)c1C +CN(C)C(C(=O)NCCCN1CCCC1=O)c1ccc(F)cc1 +O=C(c1cnc2cc(-c3ccco3)nn2c1)c1cc(F)ccc1O +Cc1cc(N)nc(C2(C)CCCN2C(=O)Cc2ccc(F)cc2)n1 +Cc1cccc(C(=O)NC(C)C(=O)OCc2cccc(C#N)c2)c1 +Cc1ccc(CN(C)S(=O)(=O)c2ccc(F)c(F)c2)s1 +COCCCNC(=O)Cn1c(=O)c(C)nc2ccccc21 +COC(=O)C(NC(=O)c1cn2cccnc2n1)c1cc(F)ccc1F +N#Cc1cccc(CNC(=O)NCc2ccc3c(c2)OCO3)c1 +CN1C(=O)CC(C(=O)N2CCCC2)C1c1ccc(F)cc1 +Cc1ccc(NC(=O)CN(C)S(=O)(=O)Cc2ccon2)cc1 +CCOc1ccccc1CNC(=O)c1ccc(N(C)C)nc1 +CC(Oc1cccc(C#N)c1)C(=O)NCc1cscn1 +CC(C)Cc1cc(C(=O)N2CCNC(=O)C2c2cccc(F)c2)on1 +CC(C)Cn1cc(NCC=Cc2ccc(C#N)cc2)cn1 +Cc1nc(SC2CCOC2=O)c2c(C)c(C)sc2n1 +O=C(Nc1ccc2[nH]c(=O)sc2c1)c1ccc2c(c1)OCO2 +CNc1ccc(C(=O)NCc2ccc(C)cc2)nn1 +CCOc1ccc(OCC(O)Cn2nnc3ccccc3c2=O)cc1 +Cc1ccc(-n2ccnc2)c(C(=O)NCCc2c[nH]c3ccccc23)c1 +COc1cc(C(=O)OCCn2nc(C)cc2C)ccc1C +COc1ccc(OC)c(CC(=O)Nc2ccccc2-n2cncn2)c1 +O=C(Cc1ccon1)N1CC=C(c2ccccc2Cl)CC1 +O=C(COc1ccccc1)Nc1ccc(-c2ccccn2)cn1 +O=C(NC1CCS(=O)(=O)c2ccccc21)c1ccc(=O)[nH]c1 +O=C(CN1CCc2sccc2C1)Nc1nnc(C(F)(F)F)s1 +Cc1ccc(S(=O)(=O)Nc2ccccc2O)s1 +CC(CC(=O)Nc1cccc(NS(N)(=O)=O)c1)c1ccccc1 +N#Cc1ccccc1NCCC(=O)c1cc(F)ccc1F +Cc1ccc(NC(=O)c2cnn(C(C)C)c2N)s1 +CC(C)(C)C(NC(=O)C1CN(Cc2ccccc2)CCO1)C(N)=O +Cc1nn(C)c(C)c1C(=O)NCCc1cccs1 +O=C(c1ccc(F)c(F)c1)N1CCC(Oc2ncccn2)CC1 +Cc1cc(NC(=O)c2ccco2)nc2nc(C(F)(F)F)nn12 +COc1ccc(C(=O)NCc2ccc(NC(=O)C(C)C)cc2)cc1 +Cc1cnn(CCCNC(=O)C2CCCCC2C(=O)N2CCCC2)c1 +N#Cc1ccccc1S(=O)(=O)Nc1ccc(F)cc1 +c1cnnc(N2CCCN(Cc3cnc4cnccn34)CC2)c1 +O=C(Cc1cccs1)Nc1ccccc1NC(=O)Cn1cnnn1 +COc1ccc(NC(=O)NC(C)c2ccc3c(c2)CCC(=O)N3)cn1 +COc1ccc(C(=O)NCC(O)c2c(C)cc(C)cc2C)cc1 +CCOCC(=O)N1CCCC1c1nnc2n1CCCCC2 +CC(C)(CNC(=O)c1n[nH]c2c1CCC2)c1ccncc1 +CC(=O)Nc1cccc(NC(=O)C2(C)CC2(Cl)Cl)c1 +Cn1nnnc1SCCC(=O)NC(C#N)C(C)(C)C +CCc1ncc(CN(C)C(=O)Nc2c(CC)cccc2CC)s1 +C#CCN1CCC(C(=O)NCc2ccc(OC(C)C)c(F)c2)CC1 +N#CC(NS(=O)(=O)c1ccccc1Cl)c1cccs1 +CS(=O)c1ccc(NCC=Cc2ccc(C#N)cc2)cc1 +O=C(COc1ccc(F)cc1)Nc1cc(N2CCOCC2)ncn1 +CNC(=O)c1cc(C)ccc1NC(=O)c1ccc(C)c(NC(C)=O)c1 +CCOc1ccc(C2=Nc3c(C#N)cnn3C2NC2CCCC2)cc1 +CC(O)CNC(=O)CSc1ccc(F)c(F)c1 +COc1cccc(C2NCCc3cccc(F)c32)c1 +O=C(CC1CCN(c2cccnn2)CC1)NC1CCOCC1 +CN(Cc1cccc(F)c1)S(=O)(=O)c1ccc(F)c(F)c1F +Nc1cc(-c2ccco2)nn(CC(=O)N2CCc3ccccc32)c1=O +CCOC(=O)C1CCN(C(=O)c2ccc(C)cc2Cl)CC1 +CC(C)CNC(=O)NCCCn1cnc2ccccc21 +Cn1ncc(-c2nc(C3CC3)no2)c1NC(=O)c1cc(Cl)ccn1 +CCC(C(=O)NC)N(c1cccc(OC)c1)S(C)(=O)=O +CCC(C)C(C)NC(=O)N1CCCN(C(=O)c2cccc(F)c2)CC1 +COc1ccccc1NC(=O)CC(C#N)c1cccc(F)c1 +COc1cc(CNC(=O)c2ccc(O)c(Cl)c2)ccc1O +COCc1c(C(=O)N2CCC2c2ccc(F)cc2)noc1C +Cc1ccc(NS(=O)(=O)c2ccccc2N)nc1 +NS(=O)(=O)c1ccc(Cn2ccnc2-c2cccc(F)c2F)cc1 +Cc1noc(C)c1C(C)NC(=O)c1cc(Cl)ccc1O +CC(C)(C)OC(=O)N1CCC(c2nc(C3CC3)n[nH]2)CC1 +CCCC(=O)Nc1cccc(NC(=O)c2ccc(OC)cc2)c1 +CCOC(=O)Nc1nnc(-c2ccc(OC)c(OC)c2)s1 +O=C(c1cccnc1OCC(F)F)N1CCOC2CCCCC21 +COc1cc(-c2noc(COCc3ccccc3Cl)n2)ccn1 +CCn1ccc2oc(C)c(C(=O)N3CCCC(C)C3)c2c1=O +CC(CNC(=O)C(C)NC(N)=O)Oc1ccccc1 +Cc1ccc(OCC(=O)Nc2ccc(Cl)c(N)c2)cc1 +Cc1ccc(NS(=O)(=O)c2csc(C(N)=O)c2)cc1 +CC(C)(NCc1ccc(F)cc1C#N)c1nccs1 +CCCSc1ccccc1NC(=O)NCc1c(C)n[nH]c1C +Nc1ccc(OCCc2cccs2)c(Cl)c1 +CC(c1ccc(Br)cc1)n1c(N)cc(=O)[nH]c1=O +Cc1cccnc1NC(=O)Cc1c[nH]c2c(C)cccc12 +CCOc1cc(C)ccc1NC(=O)CCc1nc(-c2ccco2)no1 +CC1CCCCN1C(=O)CSc1nc(N)nc(N)n1 +Cc1c(C(=O)NC(C)CC(O)c2ccco2)sc2ccccc12 +Clc1cc(CSc2nnnn2C2CC2)cc2c1OCCCO2 +COc1ccc(F)c(NC(=O)c2c(C)oc(C)c2C)c1 +CCCNC(=O)CNC(=O)Nc1c(C)cccc1C(C)C +O=C(CSc1nnnn1-c1ccc(F)cc1)c1ccc(F)cc1 +Cc1ccc(Cl)c(OC(C)C(=O)N(C)Cc2cc(C)on2)c1 +Cc1ncsc1C(=O)N1CCN(C(C#N)c2ccccc2)CC1 +Cc1ccc(NC(=O)N2CCC(n3c(C)nc4cccnc43)CC2)cc1 +CC1Sc2ccc(C(=O)N(C)c3ccccc3)cc2NC1=O +CCOc1ccccc1C(=O)Nc1sc(NC2CC2)nc1C(N)=O +Cc1ccnc(NC(=O)CC2Oc3ccccc3NC2=O)c1 +O=C1Cc2cc(NC(=O)c3ccc(Cl)c(Cl)c3)ccc2N1 +CN(C)C(=O)N1CCN(C(=O)c2cn[nH]c2)CC1 +Cc1cccc(CNC(=O)NCC(=O)Nc2c(C)cccc2C)c1 +COc1ccc(CNc2ccccc2C#N)c(F)c1 +CCCS(=O)(=O)N1CCC(NC(=O)c2cccc(C)c2O)CC1 +CC(C)NC(=O)c1ccccc1NC(=O)CNc1ccc(F)cc1 +CCC(C)C(NC(=O)c1sc(C)nc1C)C(N)=O +COc1cccc2c1cc(C(=O)Nc1nc(C)cs1)n2C +O=C(NCc1nc2ccccc2[nH]1)c1cc(-n2ccnc2)ccn1 +O=C(NCCO)c1nc(-c2ccccc2)n2c1CCCCC2 +O=C(c1ccco1)N1CCC(C(=O)N2CCOCC2)CC1 +CC(C)c1nc(CCNC(=O)CCc2ccccc2)cs1 +CCC(Cn1c(=O)oc2ccccc21)NC(=O)c1cccs1 +COc1ccc(C)cc1NC(=O)CCC(=O)c1cccs1 +CCN(CC)C(=O)CSc1ccc(C)cc1C +Cc1cccc(OCC(O)CNC(=O)c2cccc(C)c2O)c1 +O=C(c1cc(=O)c2ccccc2o1)N1CCC(N2CCNC2=O)CC1 +CCCC1CN(C(=O)Nc2ccc3c(c2)CCC(=O)N3)CCO1 +CCc1ccc(NC(=O)C(C)S(=O)(=O)c2ccc(O)cc2)cc1 +Cc1cc(C(=O)COc2cccc(Cl)c2)c(C)[nH]1 +Cc1cc(NC(=O)NC(CO)c2ccccc2)no1 +Cc1cnc(NC(=O)c2cccc(Cl)c2)s1 +Cc1cc(-c2nnc(NC(=O)c3cc(-c4ccco4)n[nH]3)o2)c(C)o1 +Cc1ccccc1CN(C)C(=O)Cn1ccnc1-c1cnccn1 +COc1ccc(NC(=O)C(c2ccccc2)n2cnnn2)cn1 +O=C(Nc1ccc(-n2ncc3ccccc32)cc1)C1CC1 +C=CCN(C)C(=O)c1csc(NC(=O)c2ccc(F)c(F)c2)n1 +Cc1ccc(C(=O)CCC(=O)Nc2ncc(C(N)=O)s2)s1 +Cc1csc(=O)n1CC(=O)N(Cc1ccc(C#N)cc1)C(C)C +COc1ccc(CNc2ccccc2C#N)c(OC)c1OC +COC(=O)c1cc(Cl)cc2c1OCC(=O)N2C +CSc1nnc(CNC(=O)Nc2cccc(C(C)=O)c2)n1C(C)C +C=CCc1ccccc1OC(=O)C1CC(=O)N(C(C)C)C1 +CCOC(=O)c1nn(CC)c2c1CN(CC1N=CC(C)=N1)CC2 +CSc1ccccc1NC(=O)CSc1nc(C)cc(N)n1 +CCOc1ccc(C(=O)Nc2cccn(C)c2=O)cc1 +O=C1CSc2cc(C(=O)NCCCN3CCCC3=O)ccc2N1 +CCOCC1=NC(=O)C2C(=N1)c1ccccc1CC21CCCC1 +CCN(CC(C)C#N)C(=O)Nc1ccc(OC)nc1 +NC(=O)c1c(NC(=O)c2ccc(Cl)cc2)sc2c1CCC2 +CCNC(=O)c1ccc(NC(=O)Cc2csc(CC)n2)cc1 +CC(C#N)NS(=O)(=O)c1ccc2c(c1)N(C)CCC2 +Fc1ccccc1N1CCN(c2ccc3nncn3n2)CC1 +CCN(CC)c1ccc(C(F)(F)F)cc1NC(C)=O +CC(NC(=O)Cn1ncc2ccccc2c1=O)c1nc2ccccc2[nH]1 +CNC(=O)CN1c2ccccc2C(=O)N(C)C1c1cccc(F)c1 +Cc1ccc(CNC(=O)NCc2noc3ccc(C)cc23)cc1 +O=C(c1cscn1)N(Cc1ccccc1)C(CO)C1CC1 +CCCNC(=O)c1cccc(CNC(=O)C2(C#N)CCCCC2)c1 +Cc1cc(C)c(C(=O)NCCOc2cccc(F)c2)c(=O)[nH]1 +Cc1cc2nc(C3CCCN(Cc4ccccc4F)C3)cc(N)n2n1 +CC1CCCN(S(=O)(=O)NC2CCc3ccccc32)C1 +Cc1ccccc1-c1noc(C2CCN(Cc3ccncc3)C2)n1 +COc1cc2[nH]c(=O)n(CCCN3CCOCC3)c(=O)c2cc1OC +Cc1noc(C(C)OC(=O)c2cc(F)ccc2F)n1 +CCOc1nc(C)nc(NCc2ccc(OC)cc2)c1N +COc1ccc2ccccc2c1Cn1cnc2nccnc2c1=O +CCC(C)Oc1ccc(NC(=O)c2cc(C)n[nH]2)cc1 +COc1c(F)cc(NC(=O)NC2CCOC(C3CC3)C2)cc1F +CC(=O)Nc1ccc(F)c(C(=O)NCCCn2nc(C)cc2C)c1 +CCOC1CN(C(=O)c2ccncn2)C2CCCOC12 +CC(Nc1ncnc2c1cnn2CCC#N)C(=O)N1CCCCC1 +COc1cc2nc(C(C)O)n(CC#N)c2cc1OC +CC(C)c1cc(=O)n2ncc(-c3ccccc3)c2[nH]1 +COCc1nnc(NC(=O)C2CC(=O)N(C)C2c2ccccc2)s1 +Cc1ccc(C(=O)NC2CCc3cc(F)ccc32)c(=O)[nH]1 +CCn1ncc2c1NC(=O)CC2c1cnc(-c2ccccn2)nc1 +CC(NC(=O)c1n[nH]c2ccccc12)c1ccc(S(C)(=O)=O)cc1 +O=C(CCc1nc2ccccc2[nH]1)N1CCC2(CC1)OCCO2 +Cc1ccc(CC(=O)NCCc2cc(F)cc3c2OCOC3)cc1 +Cc1nn2c(C)c(-c3ccno3)nnc2c1-c1ccccc1 +Cc1cccc(CN2CCOCC3(CNC(=O)CO3)C2)n1 +COCCN1CC(C(=O)N(C)c2cc(C)ccc2C)CC1=O +CN(Cc1ccco1)C(=O)c1cc2c([nH]c1=O)CCC2 +CS(=O)(=O)N1CCC(C(=O)NCCOc2ccc(F)cc2)CC1 +COC(C)(C)c1noc(CCNC(=O)c2n[nH]c3ccccc23)n1 +O=C(c1c(F)cccc1Cl)N1CCN(Cc2ccncc2)CC1 +FC(F)(F)Oc1ccccc1NCC1CCCO1 +O=C(NCc1cn2c(n1)SCC2)c1cn2cccnc2n1 +Cc1ccc(S(=O)(=O)Nc2ccccc2N2CCCC2=O)cc1C +CC(C)c1nnc(SCc2ccc(Cl)cc2)n1N +Cn1cc(C(=O)N2CCC(c3cc4cccnc4c(=O)[nH]3)CC2)cn1 +CCCOc1ccc(CSc2nc(CC)n[nH]2)cc1 +CC(NC(=O)CCCNC(=O)c1ccc(Cl)cc1)c1ccccc1 +CCOc1ccc(C(=O)Nc2ccccc2Cl)nn1 +CCOC(=O)CN(C(=O)c1ccc2ccccc2n1)C1CC1 +CCCc1nc(C(=O)NC2CCC3CCCC32)cs1 +CN(CC(F)F)C(=O)NCC1(c2ccc(F)cc2F)CC1 +O=C(c1[nH]ncc1Br)N1CCCC(c2ccn[nH]2)C1 +CCOC(=O)c1cnn(C2CCCN(C(=O)C3CCC(C)CC3)C2)c1 +CCCCc1c(CO)nnn1-c1cccc(SC)c1 +Cc1cccc(NC(=O)C2CCCN2C(=O)OC(C)(C)C)n1 +NC(c1nc2c(s1)CCC2)c1ccc(O)cc1Cl +O=C(CCCc1ccccc1)N1CCC(Oc2cnccn2)CC1 +CC1CN(C)CCN1C(=O)c1cccnc1Oc1cccnc1 +CCN(CC(=O)N(C)C)C(=O)c1cc2c(ccc3ccccc32)[nH]1 +Cc1cc(C)c(Cn2nc3ccccn3c2=O)c(C)c1 +CC(C)CCNC(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +CCn1c(C)cc(C(=O)NCCNC(=O)C2CC2)c1C +Cc1c(C(=O)NC(C)(C)C#N)oc2c(Cl)cccc12 +CN(C(=O)Cn1c(CCCO)nc2ccccc21)c1ccccc1 +O=C(C1CC1)N1CCCC2(CC(Oc3ncccn3)CO2)C1 +C=CCOC(C)C(=O)Nc1ccc2c(c1)NC(=O)CO2 +CC(C)Cc1cc(C(=O)N2CCCC2c2nc3ccccc3[nH]2)no1 +CCC(=O)Nc1ccc(NC(=O)C(CC)OC)cc1 +CCC1(CO)CCN(C(=O)c2cc(C(C)C)nc3onc(C)c23)CC1 +N#Cc1ccccc1C(=O)c1cccc(CN2CCOCC2)c1 +CCn1nc(C(C)C)cc1C(=O)N1Cc2ccccc2C1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2cccc(C)n2)c1C +CC1(C)CN(C(=O)c2cncn2-c2ccc(F)cc2)CCO1 +CCC(=O)Nc1ccc(S(=O)(=O)N(C)CC2CCCC2)cc1 +Cc1cc(NC(=O)CC#N)n(-c2nc3ccccc3[nH]2)n1 +CC(=O)Nc1ccc(OS(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)cc1 +COC1CCN(C(=O)c2cnn(Cc3ccccc3Cl)c2)CC1 +COc1ccc(CC2CN(Cc3ccco3)CCO2)cc1 +CCC(NC(=O)Nc1ccccn1)c1ccc2c(c1)OCCO2 +O=C(Nc1ccc(Br)cc1Cl)c1cscn1 +CC(C(=O)NCCC1=CCCCC1)N1CCOC(Cn2cncn2)C1 +CNC(=O)c1cc(NC(=O)c2cccc(N(C)C)c2)ccc1F +COc1ccc(OC)c(C(O)CNc2cccc(F)n2)c1 +CN(CCOc1ccccc1F)C(=O)c1scnc1C1CC1 +O=C1CN(C(=O)CCCc2ncc(-c3ccccc3)o2)CCN1 +COCc1csc(NC(=O)c2cnn(-c3ccncc3)c2C)n1 +C=CCOc1ccc(C(=O)N2CC(C)OC(C)C2)cc1 +Cc1nnc(CSc2nnc3c(Cl)cc(Cl)cn23)o1 +NC(=O)c1ccnc(NCCc2coc(-c3ccccc3)n2)c1 +COC(=O)CSc1nc2sc3c(c2c(=O)n1C)CCCC3 +COCCn1cc(NC(=O)C(C)c2ccsc2)cn1 +COc1cccc(C(=O)N2CC3CC2C(=O)O3)c1OC +Cc1ccc(C(=O)N(C)C)cc1OCc1cn2ccccc2c1C#N +CCc1cnccc1C(=O)OCC(=O)N1CCc2ccccc2C1 +CCOC(=O)c1cc(-c2ccc(OC)cc2)nn1CCO +COCc1ccccc1CNC(=O)c1ccc(C(=O)N(C)C)cc1 +CS(=O)(=O)c1ccc(OCC2CCOC2)c(N)c1 +CCCn1ccc2cc(NC(=O)c3cc(C)n[nH]3)ccc21 +COc1cc(CC(=O)NCC(O)c2cccc(Cl)c2)ccc1C +CCN(CC)c1ccc(C(=O)NCc2ccc(OC)cc2)cc1 +COc1cc(C(C#N)N2CCOC(C)C2)cc(OC)c1OC +CN(CCOCC1CC1)C(=O)NCc1ccco1 +CN(CC(=O)OCC1CCC(=O)N1)Cc1ccccc1 +CCCNc1ccc(C(F)(F)F)cc1NC(=O)Cc1ccon1 +O=C(c1cccs1)N1CCCC1Cn1nnc(-c2cccnc2)n1 +CCOC1CCN(C(=O)C(c2cccc(C)c2)N(C)C)CC1 +CC1CCCCC1N(C)C(=O)c1ccc(-c2ccncc2)[nH]c1=O +CCOCC1(CNc2cc(C)nc3c(C)c(C)nn23)CC1 +CC(NC(=O)c1ccoc1)C(=O)NC(C)c1nc2ccccc2[nH]1 +CCC1CN(C(=O)NC2CCC(O)CC2)CCO1 +Cc1cc(=O)c(C(=O)N(C)CCC(F)(F)F)nn1-c1ccccc1 +Cc1ccoc1C(=O)NCc1ccc(OC2CCCC2)nc1 +Cc1nc(C(F)(F)F)ccc1C(=O)N(CC(N)=O)C1CCCC1 +c1ccc(CN2CCN(Cc3csc(-c4ccco4)n3)CC2)nc1 +Cc1nc(C)c(CC(=O)NC23CC4CC(CC(C4)C2)C3)c(=O)[nH]1 +COc1ccc(C(=O)N2CCCCC2)cc1Cl +CCN(C(=O)c1cn(C)nc1C)c1cccc(C)c1 +O=C(COc1ccccc1CN1CCOC2(CCC2)C1)N1CCCC1 +CC(=O)N1CCCC1C(=O)Nc1ccccc1Cc1ccccc1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)Nc1ccc(F)c(F)c1 +COc1cc2cnc(-c3ccccc3)c(O)c2cc1OC +CNC(=O)c1ccc(CNC(=O)CCOC(C)C)cc1 +Cc1cc(C)c(C#N)c(SC(C)C(=O)Nc2ccnn2C(C)C)n1 +O=S(=O)(c1ccc(NCCOc2ccccc2)cc1)C(F)F +O=C(CCCc1ccccc1)Nc1cnn(CC2CC2)c1 +Cc1cc(C(C)NC(=O)Cc2ccc(F)cc2)c(C)o1 +Cc1nc2c(s1)C(N(C)Cc1ccc(OC(C)C#N)cc1)CCC2 +COc1cc(C(C)=O)ccc1OCc1nc(C(C)(C)OC)no1 +CC(C)OCCC(=O)N(C)C(C)c1ccc(F)c(F)c1 +c1ccc(C2(c3nnc(CC4CCCCC4)o3)CCOCC2)cc1 +O=C1CCC2(CCCN(C(=O)c3ccccn3)CC2)N1 +O=S(=O)(NCC1CCC1)c1cccc(Cl)c1 +COc1ccc(NC(=O)C(O)c2ccc(F)cc2)cc1Cl +CCN(CCO)C(=O)c1cnn(-c2ccc(F)cc2)c1C(C)C +COc1ccc(C(=O)n2nc(C(F)(F)F)nc2N)cc1 +COCC(C)NC(=O)C12CCC(c3nc4ccccc4nc31)C2(C)C +CCOCC(O)CN1CCN(C(=O)c2cccc3ncccc23)CC1 +N#Cc1ccc(C(=O)N2CCCC2c2cccs2)cc1 +Cc1nc2ccc(C(=O)N(CCC#N)CCC#N)cc2nc1C +COCCOc1cc(C)ccc1NC(=O)N1CCCC(C)C1CO +CCCn1cc(S(=O)(=O)N(C)C(C)C2CC2)c(N)n1 +O=C(NCC(=O)N1CCCC1)c1nc(C2CC2)n(-c2ccccc2)n1 +CCN(C)C(=O)C(C)NS(=O)(=O)c1ccccc1C(F)(F)F +CN(C)C(C(=O)NCc1ccoc1)c1c(F)cccc1F +O=C(Nc1ccc(CC(=O)N2CCCC2)cc1)c1cccc(Cl)c1 +NC(=O)c1cc(S(=O)(=O)Nc2ccccc2)ccc1N +CCc1noc(CC)c1CNC(=O)c1cc2ccc(C)cc2nc1C +CCn1c(C)nnc1SCCNc1cc(C2CC2)ncn1 +CC(C)c1nnc2n1CCN(C(=O)c1cccc(-n3cccc3)c1)C2 +O=C1CCCN1CCCNc1ncnc2sc3c(c12)CCCC3 +CCCn1cc(Br)cc1C(=O)N(C)CC(C)C#N +COc1ccccc1CN(Cc1cccs1)C(=O)c1cnccn1 +CC(=O)Nc1cccc(NCC(=O)N2CCOCC2)c1 +CCOC(=O)CNS(=O)(=O)c1cc(C)c(OC)cc1C +CC(=O)Nc1ccccc1OCc1cc(Cl)c2c(c1)OCO2 +CNC(=O)NCC(=O)NCCOc1cccc(C(F)(F)F)c1 +CCCC1CN(C(=O)Nc2ccccc2N(C)C)CCO1 +Cc1cc(C2CN(Cc3cccn3C)CCO2)ccc1F +CC(C)Oc1cccc(C(C#N)N2CCC(O)CC2)c1 +CCOC(=O)c1cnn2cc(-c3ccccn3)cnc12 +Cc1ccc(-c2cnn(CC(=O)NCc3ccco3)c2)cc1 +CCC(C)N(CCOC)C(=O)c1cc(N)cn1C +CCC(NC(=O)c1c(Cl)cnn1C)c1ccccc1 +Cc1ccc(CNS(=O)(=O)c2ccc(-c3cnc(C)o3)cc2)cc1 +O=C(Nc1ccccc1N1CCC(O)CC1)c1ccc2c(c1)OCO2 +CN(C)S(=O)(=O)Nc1ccc2c(c1)oc1ccccc12 +Cc1cnc(C2NCCc3ccc(Cl)cc32)cn1 +Cc1ccc(Br)cc1NC(=O)NCc1ccoc1 +Cc1ncc(N)cc1C(=O)Nc1ccc(Br)cc1 +CC(=O)N(C)c1cccc(NC(=O)N2CCc3cc(F)ccc3C2)c1 +C#CCNC(=O)NCc1ccc(OCC(F)(F)F)nc1 +O=C(CNC(=O)c1ccc(Br)cc1)Nc1ccccn1 +COc1ccc(NC(=O)Cn2nnc(-c3ccccc3)n2)cc1 +O=C1NCCN1C1CCN(C(=O)C2(c3ccccc3)CCCC2)CC1 +CCC(C)NC(=O)Nc1cc(OC)ccc1Cl +Cn1cnc(CNC(=O)NCc2ccc(F)c(Cl)c2)n1 +NC(=O)c1ccccc1NC(=O)C1COc2ccc(F)cc2C1 +CN(C)c1cccc(C(=O)N2CCN(c3ccccc3O)CC2)c1 +COCCCNC(=O)c1ccc(Oc2ccccc2Cl)o1 +Cc1cc(C)n2nc(C)c(C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)c2n1 +CC(=O)Nc1ccc(NC(=O)C2CCCN(S(C)(=O)=O)C2)cc1 +Cc1ccc(S(=O)(=O)CCC(=O)Nc2ccncc2)cc1 +CN(C)C(=O)c1ccc(Cn2ccc3ncccc3c2=O)o1 +O=C(Nc1cccc2ccc(O)cc12)c1ccccc1 +Nc1ccc(NC(=O)c2ccc(Br)cn2)cn1 +N#Cc1ccc(CN2CCN(C(=O)CN3CCOCC3)CC2)c(F)c1 +Cn1nc(C(=O)Nc2n[nH]c(-c3cccc4ccccc34)n2)ccc1=O +COC(=O)c1ccc(Cn2ccc(=O)c3cc(C)ccc32)o1 +C=CCn1cc(O)c(=O)cc1CN1CCOCC1 +O=C(CNC(=O)c1ccccc1Cl)NCc1ccccc1F +Cc1nccc(C(=O)NCCNC(=O)COc2ccccc2)n1 +COc1cc(C(C)O)ccc1OCc1nnc(C)o1 +CCc1onc(C)c1NC(=O)c1sc(-c2ccc(C)o2)nc1C +Cn1nnc(C#N)c1-c1cccc(Br)c1 +CCc1nc2n(n1)CCCC2NC(=O)C1CC(=O)N(CC)C1 +O=C(CCSc1ccccc1F)NCC(O)c1ccncc1 +COc1ccc(C(=O)N(CCc2cccs2)C2CC2)cc1 +Cc1csc(=NS(=O)(=O)c2cnn(C(C)C)c2)[nH]1 +CC1CCN(C(=O)c2ccc(Br)cc2O)CC1 +Nc1ncc(Br)cc1C(=O)NCCc1cccnc1 +CCn1cc(NC(=O)Nc2nccs2)c2ccccc21 +CCC(=O)NCC(c1ccccc1)c1ccccc1 +COc1ccc(SC(C)C(=O)N2CCC(C(N)=O)CC2)cc1 +Cc1nc(CNC(=O)N2CCOCC2C2CC2)sc1C +Cc1n[nH]c(-c2cccc(CNC(=O)CC3CCC3)c2)n1 +CCCNC(=O)C1CCN(c2ccc(F)cc2)C1=O +COc1cc2oc(C(=O)Cc3ccccc3)cc2cc1N +COCCNC(=O)CNC(=O)C1CC1c1ccc(C)s1 +Cc1[nH]nc2c1NC(c1cccc(OC3CCCC3)c1)NC2=O +CC(=O)NC1CCCN(C(=O)NCc2ccco2)C1 +Nc1c(Cl)cc(NC(=O)c2scnc2C2CC2)cc1Cl +COc1cc(Cl)c(C)cc1NC(=O)c1ccc(-n2cnnn2)cc1 +COc1c(NS(=O)(=O)Cc2ccccc2)c(C)nn1C +NC(=O)c1csc(C(=O)NC2CCN(c3ccccc3)CC2)c1 +COc1cccc(C2NCCc3c(O)ccc(F)c32)n1 +CN(CCCc1ccccc1)S(=O)(=O)c1ccc(N)cc1 +COC(=O)N1CCC(NC(=O)COc2ccc3ccccc3c2)CC1 +CCOc1ccccc1NC(=O)Cn1nnc(-c2ccccc2)n1 +CCc1cc(-c2nc(C(C)(C)NC(C)=O)no2)sc1C +COc1ccc(S(=O)(=O)NCc2ccc(C)cc2)cc1NC(C)=O +CC1(C(N)=O)CN(C(=O)c2cccc(-n3cnnc3)c2)CCO1 +Cc1ccc(CCCCC(=O)Nc2c(C(N)=O)n[nH]c2C)cc1 +CC(C)S(=O)(=O)c1cc(N)cc2c1ccn2C +CCOc1ccc(C2CC(=O)Nc3c2c(=O)nc(SC)n3C)cc1 +CNC(=O)NCC(=O)NCC(C)c1cccs1 +N#Cc1nnn(-c2cc(Cl)cc(Cl)c2)c1C1CCCO1 +CCCN(Cc1ccccc1)C(=O)c1cc2ccccc2oc1=O +Cc1cccc(NC(=O)Cc2nc3scc(C)c3c(=O)[nH]2)c1 +c1ccc(Cn2ncc3c(NCc4ccccn4)ncnc32)cc1 +CCc1ccc(NC(=O)c2ccc(OC)c(N)c2)cc1 +Cc1ccc(Cn2nccc2NC(=O)CCSc2nnnn2C)o1 +CC(C(=O)NC(C#N)C1CCOC1)N1CCc2ccccc2C1 +NC(=O)CCCNC(=O)C1CC(=O)N(c2ccccc2Cl)C1 +Cn1c(=O)c2ccccc2n(NC(=O)OC(C)(C)C)c1=O +CCN(C)c1ccc(C(=O)NCCNC(C)=O)cc1 +N#CCc1ccccc1C(=O)NCCN1CCOCC1 +CCOC(=O)CCC(C)NC(=O)N1CCCC(C)CC1 +CCCn1cc(C(=O)NCC2CC2)c2ccccc21 +COc1ccc(C=Cc2cc3c(cc2OC)OCCO3)cc1O +CN(CCc1ccccn1)C(=O)c1cc(Br)ccc1O +CN(CCO)S(=O)(=O)c1ccccc1C(F)(F)F +Cc1ccc(C2(Cc3ccccc3)NC(N)=NC2=O)o1 +Cn1c(C(=O)NCC2CC2)cc2cnc3[nH]ccc3c21 +CC(C)N(C(=O)CSc1ncn[nH]1)C1CCCCC1 +CCNC(=O)c1ccccc1NC(=O)C(C)NC(N)=O +O=C(NCc1ccncc1)N(CCCO)C1CCCc2ccccc21 +Cc1ccc(C(O)CCC(=O)NCc2cccnc2)c(C)c1 +CC(C)(C)CC(=O)NCC(O)c1ccc2c(c1)CCO2 +COCc1cc(C(=O)Nc2ccc3c(c2)COC3)no1 +CCN(CC)C1CN(Cc2nccs2)C2CCCOC12 +Cc1ccc(-c2nn(CCC#N)cc2C(=O)OC(C)C)cc1 +Cc1ccsc1C(=O)OC(C)C(=O)N1CCc2sccc2C1 +CCOc1ccc2cccc(NC(=O)c3cc(-c4ccco4)on3)c2n1 +O=C(N1CCC2(CC1)CC2)C1(c2cccc(F)c2)CCOCC1 +Cc1occc1-c1n[nH]c(C(N)c2ccc(F)cc2)n1 +O=C(NC1CCSc2c(F)cccc21)c1ccnc2ccccc12 +O=C(CCCC(O)c1ccc(Cl)cc1)NC1CCCC1 +Cc1cc(C(=O)N(C)C2CCCC2)c2c(C)nn(C)c2n1 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+O=C(Cc1ccc2c(c1)OCCO2)NCCc1ccco1 +CCc1ccc2c(COC(=O)c3cc(C)no3)cc(=O)oc2c1 +COc1cccc(CC(=O)Nc2cccc3c2NCCC3)c1 +CNC(=O)NCC(=O)Nc1cnn(Cc2ccccc2)c1 +O=C(Cc1nc(-c2ccccn2)n[nH]1)NCCc1ccccc1 +CS(=O)(=O)c1ccc(NS(=O)(=O)c2cc(F)cc(F)c2)cc1 +CC(=O)NC(c1cccc2ccccc12)n1nnc2ccccc21 +COc1ccc(C)cc1NC(=O)c1cccnc1N1CCCCC1 +Cc1ccc(Cn2ccsc2=NC(=O)c2ccc(C)[nH]c2=O)cc1 +Cc1cc2oc3c(c(=O)c2cc1C)C(c1cccc(O)c1)NC3=O +Cc1noc(C)c1C(C)NC(=O)NCCCC1CCCCO1 +COCc1c(C(=O)N2CCCCC2C)oc2ccccc12 +CCOc1ncccc1NC(=O)c1ccc(NC(C)=O)cc1 +Cc1noc(C)c1Cn1nnc(C#N)c1-c1cccnc1 +CCN(CC)C(=O)Cn1c(=O)oc2cc(CO)ccc21 +CC(Cc1c(Cl)cccc1Cl)NC(=O)c1cc[nH]c(=O)c1 +Cc1nnc(SC(C)C(=O)c2ccc(Cl)cc2)o1 +O=C(Nc1ccncc1)c1cnc(Cc2ccccc2)s1 +O=C(Nc1ccc(C(=O)NC2CCCC2)cc1)NC1CCCC1 +N#CCn1ccc(NC(=O)CCc2ccc3c(c2)OCO3)n1 +CC(C)n1nccc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +COc1ccc(C(O)C(C)NC(=O)COc2ccc(F)cc2)cc1 +CC(C)CCc1noc(CSc2nnnn2C2CCOCC2)n1 +COc1ccccc1CNC(=O)c1csc(-c2ccncc2)n1 +CN(CCc1cccc2ccccc12)C(=O)C(C)(C)O +O=C(Cc1cccs1)NS(=O)(=O)N1CCCCC1 +CCOCCCNC(=O)C1CN(C(=O)c2ccc3c(c2)OCO3)C1 +O=C(NCc1ccncc1)NCC(O)c1ccc2ccccc2c1 +CN(C)c1ccc(NC(=O)c2cc(F)cc(Br)c2)cn1 +CC(C)Oc1cccc(CNc2ccc3[nH]nc(C(N)=O)c3c2)c1 +NC(=O)c1ccc(NCc2cc(C(N)=O)ccc2F)cc1 +O=C(Cc1c[nH]c2ccccc12)N1Cc2cncnc2C1 +CCCC(=O)Nc1cccc(CNC(=O)NC2CCCC2)c1 +O=C(Cc1cccc(F)c1F)Nc1ccccc1N1CCCC1=O +CC(C)(C)C(=O)c1ccc2c(c1)NC(=O)CC(=O)N2 +CCNC(=O)Cn1c(CO)cnc1SCc1ccc(C)cc1 +COc1cccc(F)c1C(=O)OCCNC(=O)c1ccncc1 +COc1ccc(CC2CCCN2C(=O)c2ccc(C)[nH]c2=O)cc1 +Cc1nn(C)c2nc(N(C)Cc3ccccc3-n3cccn3)sc12 +CC1(C(=O)N2CCSc3ccccc32)Oc2ccccc2NC1=O +COc1ccc(NC(=O)Cn2c(N)nc(C(C)C)cc2=O)c(OC)c1 +COCCN(Cc1cnn(C)c1)C(=O)Nc1cccc2[nH]ncc12 +COCC(C)NC(=O)c1ccc(OCc2ccccc2)cc1 +CCc1nc(C(=O)N2CC3OCCN(Cc4ccccc4)C3C2)c[nH]1 +Cc1cccnc1NC(=O)NCCCn1nc2n(c1=O)CCCC2 +Cc1cc2c(nc1C)oc1c(N3CCCCC3)ncnc12 +CC(C)c1nc(C2CCCN(C(=O)c3ccn(C)c(=O)c3)C2)no1 +CCc1cccc(C)c1N1C(=O)C(C)(C)CS1(=O)=O +COc1ccc(C(C)NC(=O)Nn2cnc3ccccc32)c(OC)c1 +Cc1ccc(C)c(C(N)c2ccc(C(C)C)n(C)c2=O)c1 +CCOC(=O)c1c(NC(=O)C2CCOCC2)sc(C)c1CC 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+Cc1ccc(C(=O)Nc2cccc(Cl)c2Cl)c(N)n1 +COc1cc2c(cc1OC)-c1c(c(C(=O)N3CCCC3)nn1C)C2 +COc1cc(C(=O)N(C)C)ccc1NC(=O)CC1=CCCCC1 +O=C(NCCc1nnc(-c2ccccc2)o1)Nc1cn[nH]c1 +Cc1ocnc1CNC(=O)Nc1ccc(C(=O)N2CCOCC2)cc1 +Cn1cc(C(=O)NCC#Cc2cccc(Cl)c2)nn1 +Cc1c(C(=O)OCCOC(C)C)cnn1-c1ccccc1 +Cc1ccc(CNC(=O)NCc2ncnn2C)c(OC(C)(C)C)c1 +COc1cccc2c1OCC(NC(=O)Nc1nc(C)cs1)C2 +Cc1cc(C)c(S(=O)(=O)N2CCCC2c2c(C)noc2C)cc1C +CCc1ccc(C2Nc3ccccc3C(=O)N2CC2CCCO2)cc1 +CC(C)OC(=O)Cn1c(=O)cc(O)c2ccc(N)cc21 +O=C1CCc2cc(NC(=O)NCC(=O)NC3CCCCC3)ccc2N1 +Cc1nn(C)c(=O)c(C(=O)Oc2ccc(F)cc2)c1C +Cn1nc(C(=O)NCc2ccc(F)c(Cl)c2)c2ccccc21 +NC(=O)COC(=O)c1ccccc1OCc1ccc(F)cc1 +CCN(CC)S(=O)(=O)c1ccc(F)c(C(=O)N2CCC(O)C2)c1 +Cc1cc(-c2ccc(S(=O)(=O)N(C)Cc3ccccc3)cc2)on1 +CCOCc1ccc(CNC(=O)c2c(C)[nH]c3ccccc23)cc1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(F)c(F)cc1Cl +Cc1cc(NC(=O)N2CCN(c3ncnc4c3cnn4C)CC2)on1 +Cc1ccc(C)c(SCCn2c(=O)oc3cccnc32)c1 +CN(C(=O)c1cn(Cc2cccc3ccccc23)nn1)C1CCOC1 +CCOc1ncccc1C(=O)NCc1ccc(OC)nc1 +CCCOc1ccc(C(N)c2nc(C)c(C)s2)cc1 +O=C(CNc1ccc(-n2cccn2)cc1)N1CCc2ccccc2C1 +CCCn1c(C)cc(C(=O)CSc2n[nH]c(N)n2)c1C +CC(=O)NC(CC(=O)Nc1cccc(-c2cn[nH]c2)c1)c1ccccc1 +COc1cccc(C(=O)NCC(C)(C)c2ccncc2)c1F +Cc1nc(C)c(COC(=O)c2cnn(-c3ccncc3)c2C)s1 +O=C(CC1C=CCC1)OCCNC(=O)c1ccncc1 +CC(C)(C)c1ccccc1NC(=O)NCCCO +CCCC(=O)Nc1cccc(NC(=O)NCc2csc(NC)n2)c1 +CCOC(CC)C(=O)NC1CCSc2ccccc21 +CS(=O)(=O)N(C(=O)CC1C=CCC1)c1cccc(O)c1 +Cn1ncc2c(SCc3noc(Cc4ccccc4)n3)ncnc21 +Brc1cncc(CNc2ccon2)c1 +COc1cc[nH]c(=NS(=O)(=O)c2ccc(F)c(Cl)c2)c1 +CCOC(=O)c1ccc(NC(=O)Cn2nnc3ccccc32)cc1 +O=c1c2nnc3c(-c4ccccc4)cnn3c2ccn1CCCO +Cc1cccc(S(=O)(=O)CCCn2cnnc2S(C)=O)c1 +Nc1cc(N2CCCC(CO)(CCCc3ccccc3)C2)nc(N)n1 +CC(CC(=O)NC1(CCO)CCC1)c1ccc(F)cc1 +Cc1cn2c3c(=O)[nH]c(=O)n(C)c3nc2n1-c1ccccc1O +O=C(CCn1ccccc1=O)NCc1ccc(N2CCCC2=O)cc1 +Cc1cccc(CN2CCN(C(=O)c3cc(C)oc3C)CC2)c1 +Cn1cc(CC(=O)C(C#N)c2ccccn2)c2ccccc21 +Cc1ccc(OC(C)C(=O)Nc2ccc(C(=O)NC(C)C)cc2)cc1 +O=C(CNC(=O)NCC1CCCC1)Nc1cccnc1-n1cccn1 +CC(=O)c1nn(-c2ccccc2)c(=O)n1-c1ccc(Cl)c(Cl)c1 +Cc1cc(C)c(NC(=O)Cn2nc3c(cc2=O)CCCC3)c(C)c1 +CC(=O)NCCNC(=O)NC(C)Cc1ccc(O)cc1 +CCOCc1ccc(CNc2ncnc3c2cnn3C)cc1 +CNS(=O)(=O)CC(=O)N1CCCc2sccc2C1 +COC(=O)c1cc(NC(=O)NCc2ccc(F)cc2)c(F)cc1F +CCCC(=O)N1CCCC1C(=O)Nc1nc2c(C)cccc2s1 +CC(=O)Nc1cccc(C(=O)OCC(=O)Nc2cc(C)ccc2C)c1 +Cc1cc(C(C)O)c2c(c1)C(NC(=O)CC(C)C)CCO2 +COc1ccc(NC(C)=O)cc1NC(=O)Cc1ccc2ccccc2c1 +Cc1cc(C(=O)N2CCN(Cc3ncc(C(C)(C)C)o3)CC2)c(C)o1 +c1ccc(-c2nnc3sc(Cn4ccnc4)nn23)cc1 +COC(=O)c1cc2ccccc2cc1NCC(=O)N1CCOCC1 +O=C(NC1CCN(c2c(F)cccc2F)C1=O)c1cc[nH]n1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cc2ccccc2o1 +Cc1c(C(=O)NCc2ccc(F)cc2)sc2ncn(C)c(=O)c12 +Cc1nc2ccc(C(=O)NCCS(=O)(=O)N(C)C)cc2nc1C +O=C(Oc1ccc2c(c1)CCC2)c1cccc(-n2cnnn2)c1 +CCC(C#N)Oc1cccc(CNC(=O)Nc2cccc(C#N)c2)c1 +COC(=O)C(C)Cn1nc(C)c(Br)c1C +CC(C)c1nn(Cc2ccccc2)c2c1C(CC#N)CCC2 +CCCCOC(=O)CN1C(=O)CNc2cc(OC)ccc21 +CCC(C)(NCC(=O)NC1(C#N)CCCCC1)c1nc(C)cs1 +CC(=O)NC(C)(C)c1noc(CSc2nnnn2C2CC2)n1 +NC(=O)c1n[nH]c2ccc(NC(=O)CCc3ccccc3Cl)cc12 +Cc1cc(CNS(=O)(=O)c2ccc(C(C)C)cc2)nn1C +COc1cc(NC(=O)c2cccc(OC)c2OC)cc(OC)c1 +CN(Cc1cccnc1)C(=O)c1ccc(NC(N)=O)cc1 +CC(C)C(=O)Nc1nnc(Cc2ccccc2)s1 +CCOc1ccc(NC(=O)N2CCOCC2C2CC2)cc1Cl +CC(=O)Nc1ccc(NCc2csc(C(C)C)n2)cc1 +O=C(c1ccnnc1)N1CC(OCc2cccnc2)C2COCC21 +NC(=O)C1CCN(c2ccc(Cl)c(Cl)c2)C1=O +COCCOc1ccc(CNC(=O)N2CCc3ccccc3C2)cn1 +CNC(=O)Cc1ccc(NC(=O)c2cc(C)ccc2C)cc1 +Cc1cc(C)n2cc(CN3CCOC(c4ccccc4)C3)nc2n1 +COC(=O)C(C)c1cc(=O)oc2c(OC)c(OC)ccc12 +Cc1cc(C)n2nc(C(=O)Nc3nnc(C4CC4)s3)nc2n1 +COCCNC(=O)N1CCCCC1c1nnc2n1CCCC2 +CS(=O)c1ccc(CN2CCNC(=O)C2c2ccccc2)cc1 +CCCC(C)NC(=O)C(C)Sc1nnnn1-c1ccccc1 +CC(=O)N1CCN(C(=O)NC(C)C)CC2(CNC(=O)C2)C1 +CC(C)(C)C(=O)N1CCN(C(=O)CCCSc2ccccc2)CC1 +O=C(COc1ccccc1Cl)Nc1ccnn1Cc1ccco1 +O=C(NCCNc1cccnc1)c1cnc(N2CCCC2)nc1 +CC1CCCC(OCC(=O)Nc2cnn(C)c2)C1 +Cc1cc(C(O)CCNS(=O)(=O)c2ccc(F)cc2C)c(C)o1 +COc1ccc(Cn2cnc3ncccc3c2=O)c(OC)c1 +CCn1cc(C(=O)NCc2cn(-c3ccc(OC)cc3)nn2)cn1 +CNC(=O)c1ccc(OC)c(NC(=O)N(C)C(C)c2ccccn2)c1 +O=C(COC(=O)c1ccoc1)c1ccc2ccccc2c1 +C#CCn1cc(C(=O)OCC)c(=O)c2cc(F)c(Cl)cc21 +Cc1cccnc1NC(=O)C1(c2ccc(F)cc2)CCC1 +COC(=O)c1cc(S(=O)(=O)N2CCOCC2)ccc1F +CC(C)S(=O)(=O)N(C)C(=O)c1cccc(OC2CCCC2)c1 +CCC1CCCN(C(=O)CCc2nc(C)no2)C1 +CN(C(=O)c1ccc2c(c1)CCC(=O)N2)C1CCCC1 +O=C(Cc1c(F)cccc1Cl)NCc1ccc2c(c1)OCO2 +Cc1cc(-c2ccc(Cl)cc2)n2ncc(C#N)c2n1 +c1cncc(-c2n[nH]cc2CNCC2CCCc3ccccc32)c1 +CN(C)C(=O)Cn1cnc2ccc(Br)cc2c1=O +CC(C)NC(=O)c1cnn(-c2cc(F)cc(F)c2)c1-n1cccc1 +CC(C)COc1ccccc1C(=O)Nc1ccccc1C(N)=O +NC(=O)c1ccc(NC(=O)c2c[nH]c3cc(F)cc(F)c3c2=O)cc1 +Oc1cc(F)c2c(c1)C(Cc1cccnc1)NCC2 +Cc1nc(NC(=O)c2cccc(NC(N)=O)c2)sc1SCC#N +CNC(=O)Cc1ccc(NC2CCC(C)CC2)cc1 +COc1ccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)nn1 +COCC(C)NC(=O)C1CC(=O)N(Cc2ccccn2)C1 +OCc1ccc(OCc2cn3ccccc3n2)cc1 +CCNC(=O)c1ccc(NCC(=O)Nc2ccccc2OC)c(C)c1 +CC(C(=O)N1CCCCCC1)S(=O)(=O)c1nncn1C1CC1 +COC(C(=O)NCCc1ccc(NC(C)=O)cc1)c1ccccc1 +CCOC(=O)c1ccc(CNC(=O)c2ccncc2F)o1 +OC(CCNc1cccc(F)c1)c1ccc2c(c1)CCC2 +CC(C)CC(NC(=O)C1CCCN1C(=O)Cc1ccccc1)C(N)=O +COC(=O)Cc1cc(=O)oc2cc(OC)c(Cl)cc12 +CCc1onc(C)c1NC(=O)N1CCCC1C1CCC1 +COc1ccc(-c2nc3nc(C)cc(N(C)CCO)n3n2)cc1 +Cn1cc(C(=O)NCCC2=CCCCC2)c(=O)c2c(N)cccc21 +CCOc1ccc(Nc2ncccc2C(=O)N(C)C)cc1 +COc1ccnc(N2CCCCC2Cn2cncn2)n1 +O=C(Cn1c(=O)[nH]c2ccccc21)Nc1ccc(F)c(F)c1 +CCCCN(C)S(=O)(=O)N(C)Cc1ccc(C)o1 +Cc1ccc(C(=O)Nc2cccc3cnccc23)o1 +Cc1ccc(NC(=O)c2cccs2)c(OCC(=O)N(C)C)c1 +Nc1ccc(Oc2nccn(C3CC3)c2=O)cc1Cl +Cn1ncc2c(=O)n(CC(=O)Oc3cccc(F)c3)cnc21 +OCc1c(-c2ccc(Br)cc2)nc2ccccn12 +COC(=O)c1cc(-c2c(O)ccc3ccccc23)nn1C +O=C(COc1cccc2ccc(=O)[nH]c12)Nc1c(F)cccc1F +CC(C)N(C)C(=O)c1ccc(S(=O)(=O)N2CCCCC2C)cc1 +Cc1cc(C)nc(SCC(=O)NC(C)C(=O)N2CCCCC2)n1 +CC1CCN(C(=O)C2(c3ccccc3)CCOCC2)CC1 +Cc1cccc(OCCCC(=O)Nc2nncs2)c1C +CCC(=O)N1CCc2cc(CNC(=O)NCc3ccccc3)ccc21 +Cc1[nH]nc(C(N)=O)c1NC(=O)Cc1ccc(OC(F)(F)F)cc1 +COC(=O)c1ccc(NC(=O)C2CC=CC2)c(OCC(F)(F)F)c1 +CCCS(=O)(=O)NC(C)c1ccc(Br)cc1 +O=C(c1cccc(F)c1)N1CCn2c(nnc2-c2cccs2)C1 +NC(=O)c1ccc(S(=O)(=O)Oc2ccc3ccccc3c2)cc1 +Cc1nc(CSc2nc(-c3cccs3)n[nH]2)oc1C +CCCCN(C)C(=O)Cc1noc2c(N)cc(CC)cc12 +CC(C)NC(=O)Nc1cccc(C(=O)N=c2sccn2C)c1 +CNC(=O)c1sc(CCN2CCCC2=O)nc1C +CCCOc1ccc(-c2cc(C(C)=O)c(=O)n(CC)n2)cc1 +O=C1OCCN1c1cccc(NS(=O)(=O)c2ccc(F)cc2)c1 +CC(=O)c1c(C)cc(C)c(Cn2cnc(C#N)c2C#N)c1C +COC(=O)CCC(=O)N1CCCc2cc(F)cc(C)c21 +CC(C)C(NC(=O)Cc1ccsc1)C(=O)N1CCc2nocc2C1 +O=C(NCCCN1CCOCC1)Nc1c(Cl)cccc1Cl +O=C(Cc1ccc(-c2ccccc2)cc1)NCCc1cnccn1 +O=C(Nc1ccccc1)C1CCCN(C(=O)NCc2ccco2)C1 +COCC(=O)N1CCN(C(C)C(=O)NCCc2cccs2)CC1 +Cc1nc(-c2cc(NC(=O)c3ccccc3F)c(C)s2)no1 +Cc1ccc(C(=O)NCC2CCCO2)cc1-n1cccc1 +O=C(Nc1ccccc1)c1nn(-c2ccccc2)ccc1=O +Cc1nnc(C2CCN(C(=O)c3ccc4c(c3)OCO4)C2)o1 +COCCCNC(=O)CNc1ccc(F)cc1Br +COCCCNC(=O)Nc1cccc(NC(C)=O)c1 +CC1CCN(C(=O)c2cc(Br)ccc2O)CC1 +Cc1ccc(NCc2cccc3c2OCCO3)cc1 +CC(C)c1ocnc1C(=O)N1CC(=O)Nc2cccnc21 +Cc1nc(C(=O)Nc2ccc(C)c(C(F)(F)F)c2)cs1 +CCCn1nc(C)c(NC(=O)N2CCCC2c2nccs2)c1C +COc1cccc(SCC(=O)NC2CCCCNC2=O)c1 +CC(NC(=O)c1cc(Br)ccc1Cl)c1ccccn1 +Cc1ccc(C(C)NC(=O)c2cnn3cccnc23)o1 +CCCCc1c(C)nc2nc(SCC(=O)NC)nn2c1C +CCN1CCN(C(=O)c2cccc(C)c2C)CCC1=O +CC1CCN(C(=O)CSc2nncn2-c2ccccc2)CC1 +O=C(Nc1ccc(C(=O)N2CCCCC2)c(Cl)c1)c1cccnc1 +COc1cc(O)c2c(=O)c(O)c(-c3ccc(OC)c(O)c3)oc2c1 +O=C(COC(=O)c1cc(Br)ccc1Cl)c1ccc[nH]1 +CCN(Cc1cccc(C)c1)C(=O)CNC(=O)NC +COC(=O)CNC(=O)c1ccn(-c2ccc(Cl)c(Cl)c2)n1 +CCN(C)C(=O)c1cccc(OC(=O)Cc2csc(C(C)C)n2)c1 +CCOC(=O)c1c(NC(=O)C(C)C)c(-c2cccc(F)c2)cn1C +CCOCCCNS(=O)(=O)c1ccc(N)cc1 +CC(=O)c1ccc(NC(=O)C(C)N2CCn3c(nn(C)c3=O)C2)cc1 +C=C(C)CN1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +CC(C)(C)c1nccc(NC(=O)c2cccnc2)n1 +CNC(=O)N1CCc2c(sc3nc(-c4ccc(OC)cc4)nn23)C1 +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)N1CCN(C)CC1 +CC(C)(C)c1noc(CCC(=O)OCc2ccccc2)n1 +C=CCn1c(=O)n(CC=C)c(=O)n(CCN2CCOCC2)c1=O +CN(C)c1cccc(C(=O)N2CC(c3nc4ccccc4[nH]3)C2)c1 +Nc1ccc(SCC(=O)NCc2ccco2)cc1 +COCCN(Cc1ccc(F)cc1Cl)C(=O)c1cc(C)n[nH]1 +CCOc1ccc(C(=O)Nc2onc3c2CC(C)CC3)cc1 +CN(CCc1ccncc1)S(=O)(=O)c1ccccc1N +COCC(=O)N(C)c1nnc(C2CCOC2)s1 +CN(CC1CCC(NC(=O)c2ccco2)CC1)C(=O)c1ccco1 +CCC(CCO)NC(=O)NCc1cccc(NC(C)=O)c1 +CCn1c(SCc2ccc(C)cc2)nc2c(=O)[nH]cnc21 +CC(C)c1n[nH]c(C2CN(C(=O)Cc3ccn(C(C)C)n3)CCO2)n1 +COc1ccccc1C(=O)Nc1cc(-c2ccccc2)nn1CCO +CC1(C)C(=O)C2(C(=O)NCc3ccco3)CCC1C2 +CC(O)CNC(=O)c1cccc(OCc2c(F)cccc2Cl)c1 +COC(=O)c1ccccc1NC(=O)c1cccc(OC)c1F +CC(C)(C)c1nc2cc(F)c(F)cc2n1CCC#N +O=C(c1ccc(Cl)cc1)N(CCO)Cc1ccccc1 +CCc1ccc(OC)c(CCN(C)C(=O)CCC#N)c1 +CCOC(=O)c1cc(S(=O)(=O)N2CCC(C)CC2)cn1C +COc1cc2[nH]c(C(=O)N3CCN(C)CC3)cc2c(OC)c1OC +CN(C)c1cc(C(=O)NC(C#N)c2ccccc2F)ccn1 +c1ccc(-c2cnc(CSc3cnccn3)o2)cc1 +COCC(c1cccc(C(F)(F)F)c1)N(C)C(=O)c1cccnc1 +CCCCn1nnc(CO)c1Cc1c[nH]c2ccccc12 +COc1ccc(S(=O)(=O)Nc2nnc(C)s2)cc1OC +Cc1nsc(NC(=O)CNC(=O)c2cc(F)cc(F)c2)n1 +CCc1nnc2ccc(N3CCCC(C(=O)NCC4CC4)C3)nn12 +Cc1cccc(NC(=O)Cn2cnc(C(C)C)cc2=O)c1 +Cc1ccc(CC2Oc3cc(N)ccc3N(C(C)C)C2=O)cc1 +FC(F)(F)c1ccnc(-c2cccc3ccnn23)c1 +CC(=O)Nc1ccc(Oc2ccc(C#N)cc2F)cc1 +CC(CC#N)N(C)C(=O)Nc1cccc(Cl)c1SCC(F)F +CCC1CCCCN1C(=O)C(C)Nc1ccc(NC(C)=O)cc1 +O=C(c1cc(Br)c[nH]1)N1CCCC1c1ccc[nH]1 +Cc1ccc(CC(=O)NCc2ccccc2C)cn1 +CS(=O)(=O)Nc1ccc(C(=O)NCCc2ccccc2F)cc1 +CCOC(=O)c1ccc(NC(=O)OC(C)(C)C)nc1 +N#CCCN(Cc1ccco1)C(=O)c1cccc2ccccc12 +CC(=O)NC(C(=O)N(C)Cc1nnc2n1CCC2)C(C)C +NS(=O)(=O)N1CCN(CCOc2cccc3ccccc23)CC1 +CC(=O)c1c[nH]c(C(=O)NCc2cnn(Cc3ccccc3)c2)c1 +CCC(C)N(C)C(=O)NC(C)c1ccc(C#N)cc1 +CC(C)(O)c1cc(CC2(NCc3ccncc3)COC2)no1 +O=C(Oc1ccc2c(c1)OCC2=O)c1ccccc1 +CCC(CC1CCCCC1)C(=O)NCc1nc(C)no1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3cc(Cl)ccn3)cc12 +CCN(C)S(=O)(=O)NCC1CCN(c2cc(Cl)ccc2C)C1 +COc1nc(C)c(C(=O)N2CCC3(CCCN(C)C3=O)C2)s1 +CCOc1ccc(C(=O)NCc2noc(C)n2)cc1OCC +Cc1c(C(=O)NCc2ccccc2)nc2cc(Cl)ccn12 +O=C(CSc1nc2ccccc2s1)N1CCC(CO)CC1 +CCc1cccc2c1N(C(=O)c1ncn(-c3ccccc3)n1)CCC2 +CCNC(=O)C(C)NC(=O)c1cc(F)c(F)c(F)c1 +COC(=O)c1cc(C#N)c(=O)n(Cc2ncc(-c3ccccc3)o2)c1 +O=C(Cn1c(=O)oc2ccccc21)NCC1(O)CCOCC1 +CCc1onc(C)c1NC(=O)NCc1nc(C(C)C)cs1 +O=C(c1ccc(Br)cc1F)N1CCCCC1 +OCCNc1ncnc2ccc(-c3ccnc4[nH]ccc34)cc12 +CC(O)CN1CCN(Cc2nnc(C3CC3)o2)CC1 +CC(C)N(C(=O)Cn1nc(-c2ccco2)cc(N)c1=O)C(C)C +CCOC(=O)CCc1ncccc1Br +Cc1cc(C(=O)N(C)C2(C#N)CCC2)c(C)n1Cc1ccccc1 +CC(C)CN1CC(C(=O)NCc2nncn2C2CCCCC2)CC1=O +Cn1c(Oc2ccccc2Br)c(C#N)c(=O)n(C)c1=O +Cc1ccccc1CS(=O)(=O)Nc1ccccc1F +Cc1nn(C)c(C)c1CCC(=O)OC(C)c1ccc2c(c1)OCCO2 +O=C(Cn1cccn1)NC(c1ccc(Cl)cc1)c1ccsc1 +CN(Cc1ccco1)C(=O)c1c[nH]c2ccc(Br)cc12 +Cc1cc(Cl)cc2c1OCC(C)(C)C(=O)N2C +CC(C)(C)OC(=O)Nc1cc(NC(=O)NCc2ccco2)ccc1F +C=CCCC(=O)Nc1ccc(Br)cn1 +c1ccc(Cc2noc(CSc3cn[nH]n3)n2)cc1 +Cc1cccc(C(=O)NCC(=O)N2CCCc3ccccc32)c1C +Cc1ccc(C)n1NC(=O)c1cccc(-n2cccc2)c1 +O=C(Nc1cccnc1-n1cccn1)c1ccccc1 +Cc1ccc(NC(=O)CC2CCC2)cc1S(C)(=O)=O +O=C(c1cc(F)c(F)c(F)c1)N1CCC(OCC2CCCO2)CC1 +O=C(NCc1ccncc1)Nc1ccc(-n2ccnc2)nc1 +CN(C)C(=O)CCNC(=O)NCc1coc(-c2ccccc2)n1 +Cc1[nH]c2ccccc2c1C(=O)NCC(=O)N1CCCc2ccccc21 +Cc1cc(C)c(C)c(OCC(=O)Nc2cccc(C(=O)N(C)C)c2)c1 +CCC(C)NC(=O)c1ccc(N2CCOCC2)cc1 +CC1CN(C(=O)NCCc2cn3ccccc3n2)CCO1 +CCOc1cc(F)ccc1NCc1cc(=O)n2ccccc2n1 +Nc1cc(C(=O)OCC(=O)NCc2ccccc2)ccc1Cl +Cc1nccc(C(=O)Nc2ccc(-c3noc(C(C)(C)C)n3)cc2)n1 +CCN(CCNC(=O)NCC(C)C)c1ccccc1C +CC(C)Cc1cc(NC(=O)C2CCCO2)n(C)n1 +CN(C)C(=O)C1CCN(c2ncnc3c2cnn3C)CC1 +C=CCNC(=O)c1ccc(N(C)S(=O)(=O)c2ccccc2)cc1 +CNC(=O)N1CC2CC(C(=O)N3CCOCC3)C(C1)O2 +CCCOc1cccc(C(=O)Nc2c[nH]c(=O)[nH]c2=O)c1 +COc1ccc(C)nc1NC(=O)NCCn1cccc1 +COc1cc2cc(C(=O)N(C)CCC#N)[nH]c2cc1OC +CNC(=O)c1ccc(COc2ccc(C)cc2C)o1 +COc1ccc(C2CCCN2C(=O)Cn2c(C)c(C)sc2=O)cc1 +c1csc(-c2noc(-c3ccc4c(c3)OCO4)n2)c1 +CC(C)(C)c1noc(CN2C(=O)c3ccccc3S2(=O)=O)n1 +CCOc1cccc(-c2ccc(C(C)=O)c(=O)n2C(C)C)c1 +O=C(CCCNC(=O)N1CC(=O)Nc2ccccc21)NCCO +CCOC(=O)CNC(=O)c1cc2cc(C)ccc2o1 +CCN1CCN(C(=O)C2(c3cc(-c4cccs4)on3)CC2)CC1 +COc1ccc(C(C)=O)cc1CC(=O)Nc1ccc(F)cc1F +CCN(CC(C)C#N)C(=O)CN1CCN(c2ncccn2)CC1 +O=C(Nc1ccc(OC(F)F)cc1)c1ccc(NC(=O)C2CC2)cc1 +Cc1ccc(-c2n[nH]c(SCC(=O)c3cnn(C)c3)n2)cc1 +COc1cc(C(N)=O)ccc1Oc1c(N)cccc1Cl +CC(C)(C)CCC(=O)Nc1ccc2oc(=O)ccc2c1 +CCOC(=O)c1ccc(NC(=O)C2CCOC2)cc1 +O=S(=O)(c1cc(F)cc(F)c1)N1CCN(CC2CC2)CC1 +c1cnn(-c2ccc(CCNCc3ccncc3)cc2)c1 +Cc1nc(C(=O)Nc2ccc3nc[nH]c(=O)c3c2)cs1 +CC(C)C(Sc1nncs1)C(=O)Nc1ccccc1F +O=C(Cc1ccccc1)N1CCN(Cc2ccco2)CC1 +CCc1cccc(C)c1NC(=O)CSc1nn2cnnc2o1 +CC(C)(C)CC(=O)N1CCC(Oc2cccnn2)CC1 +CC(NC(=O)CSc1ccccc1Cl)C(N)=O +Cn1cc(C(N)=O)cc1C(=O)OCc1nc2ccccc2n1C(F)F +CCc1ccc(C2CCCCN2C(=O)NCc2ncn(C)n2)o1 +CCc1noc(C)c1C(=O)N1CCC(NC(=O)c2ccsc2)CC1 +O=C(COc1ccc(F)cc1F)Nc1ccncc1 +COCC(=O)Nc1cc(C)nn1-c1nc(-c2ccc(C)cc2)cs1 +Cc1ccc(Cl)cc1NC(=O)COC(=O)c1ccco1 +Cc1ccn2c(=NC(=O)CCc3ccc(C)o3)[nH]nc2c1 +O=C(CCCc1cc(F)ccc1F)Nc1ccc2c(c1)C(=O)NC2 +O=C1COc2ccc(S(=O)(=O)NCCC3CCCCC3)cc2N1 +COCc1ccc(C(=O)NC(C(N)=O)c2ccccc2)o1 +O=C(C1CCc2ccccc21)N1CCCC1Cn1cccn1 +CCc1ccc(S(=O)(=O)N2CCCC(O)C2)s1 +Fc1cnc2nc(COc3ccccc3Cl)[nH]c2c1 +O=C(c1ccc(CS(=O)(=O)c2ccccn2)cc1)N1CCCC1 +Cc1cc(S(=O)(=O)NCc2cn[nH]c2)ccc1OC(C)C +CCCS(=O)(=O)N1CCCC1CC(=O)c1cnn(C)c1 +COCC(C)NC(=O)NC(C)c1cccc(Br)c1 +O=C(Nc1nc(-c2ccccc2)cs1)c1ccc(-n2cncn2)cc1 +CCc1ccccc1NC(=O)Nc1c[nH]c(=O)[nH]c1=O +Cc1ccn(CC(=O)N2CCC(C)CC2)c(=O)c1C#N +C=CCCCNc1cc(C(=O)N(C)C)ccc1Cl +Cc1nc2cc(NC(=O)C3CCCOC3)ccc2n1C +CNC(=O)NCC(=O)Nc1ccccc1CN1CC(C)OC(C)C1 +Cc1nc(CC(C)C)c(NC(=O)NC2(C)CCOC2)s1 +Cc1cccc(C)c1NC(=O)Cn1cc(C(=O)C2CC2)c2ccccc21 +CCn1cc(CN2CCN(C(=O)c3cccnc3)CC2)cn1 +Cc1ccc(CNC(=O)c2cc3c([nH]c2=O)CCCC3=O)s1 +COCCOCC(=O)Nc1ccc2nc(-c3cccc(F)c3)[nH]c2c1 +CCn1c(C(=O)N2CCOCC2)cc2c(=O)oc3ccccc3c21 +Cc1nn(C)cc1CN1CCOC(c2ccc(F)c(Cl)c2)C1 +N#Cc1cccc(C(=O)N2CCCC(CCO)C2)c1 +CCC(C(=O)Nc1c(C)cc(C)cc1C)n1c(N)nnc1SC +CCC(=O)c1cccc(S(=O)(=O)NC(C)C)c1 +N#Cc1cc(S(=O)(=O)NCC2(CCO)CCOC2)ccc1F +Cc1cc(C(=O)N2CCCC(NC(N)=O)C2)sc1C +COCC(=O)N1CCN(Cc2noc3ccccc23)CC1 +Cc1ccc2ncc(C(=O)Nc3ccc(-c4cnco4)cc3)n2c1 +CCN(CC)c1ccc(NC(=O)c2ccn(C)c(=O)c2)cn1 +O=C(OCc1ccc(Cl)cc1Cl)c1ccccn1 +CC(=O)c1ccccc1OCCn1cnc2ccccc21 +O=C(CCNC(=O)NCC(F)(F)F)Nc1ccccn1 +CCOc1ccccc1Nc1ncnc(Nc2cc(C)on2)c1N +Cc1cc(C)n2nc(SC(C)C(=O)N3CCOCC3)nc2n1 +CC(C)C(CNC(=O)Nc1cnn(C)c1)c1ccccc1 +CC(OC(=O)c1ccccc1OC(F)F)C(=O)NC1CC1 +COC(=O)CCc1csc(COc2cccc(F)c2)n1 +COc1ccc2c(O)cc(C(=O)NC3CC3)cc2c1OC +CCOc1ccc(NC(=O)Cc2ccc(NC(C)=O)cc2)cc1Cl +CN(C1(C#N)CCCC1)S(=O)(=O)c1ccc(Cl)cc1 +CCC(C)n1ncc(C(=O)Nc2nc(C(N)=O)cs2)c1C1CC1 +CNCC(=O)OCc1ccc2c(c1)NC(=O)CCO2 +CC(O)c1ccc(OCC(=O)N2CCOCC2)cc1 +CCC(Nc1cc(C)nc2ncnn12)c1ccc(OC)cc1 +CN(C)S(=O)(=O)NCc1ccc(-n2ccnc2)cc1 +COc1ccccc1-c1nnc(SCc2ccccn2)n1C +CCN(CC)C(=O)c1cc(NC(=O)COC)c(=O)n(C)c1 +CCCCOc1ccc(C(=O)C(C#N)c2ccccn2)cc1 +COc1ccc(NC(=O)Nc2cccc(NC(=O)C(C)C)c2)cc1 +Cn1cc(CCCC(=O)Nc2ccccn2)c2ccccc21 +CCc1cc(OCC(=O)OC)nc(-c2ccc(F)cc2)n1 +Cn1ncc(C(=O)N2CCN(Cc3ccccc3)CC2)c1N +CCN(CCc1nc2ccc(C)cc2[nH]1)C(=O)c1cnc(C)cn1 +O=C(NCC(O)Cn1ccccc1=O)c1ccccc1F +NC(=O)Cn1c(CCCNC(=O)c2ccccc2)nc2ccccc21 +Fc1ccc2c(c1Br)C(c1ccco1)NCC2 +CC(C)CCC(=O)NCCC(=O)Nc1ccccn1 +Cc1noc(C)c1C(C)NC(=O)Cc1cc2ccccc2[nH]c1=O +O=C(NCCCn1ccc2cccnc21)c1c(F)cccc1Cl +Cc1cc(C(=O)NCCNC(=O)c2ccc(O)cc2)c(C)n1C(C)C +CC(Sc1nc2ncccn2n1)c1nc(-c2ccco2)no1 +O=S(=O)(NC1CC1)c1cc(Cl)c(Cl)cc1Cl +CCc1cc(NCCc2ccc(O)cc2)n2nccc2n1 +CCC1c2ccsc2CCN1C(=O)Cn1c(C)c(C)sc1=O +CCNC(=O)CCCC(=O)Oc1ccc(F)cc1F +O=C(NCc1ccc2ccccc2c1)C1CCOCC1 +CCc1ccc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)cc1 +O=C(NC1CC1)c1cccc(OC(=O)c2ccnc(-n3cncn3)c2)c1 +Cc1ccc(OC(=O)CCCNC(=O)C(C)(C)C)cc1 +C=CCNC(=O)CNC(=O)c1ccc(OC)c(OC)c1 +NC(=O)CSc1ccccc1NCc1csc(C2CCCC2)n1 +Cn1cccc1C(=O)OCC(=O)c1ccc(Br)cc1 +COCCN(CC(=O)Nc1ncc(C)s1)C(=O)C1CCC1 +CS(=O)c1cccc(NC(=O)Cc2cccc(F)c2F)c1 +CCc1n[nH]c(SC(C)C(=O)N2CCN(C(C)=O)CC2)n1 +N#CCCSc1ccccc1NC(=O)c1cccc(-c2ccoc2)c1 +COc1cccc(C2CC(O)=Nc3c2cnn3C2CCCC2)c1 +Cc1ccccc1OCCCC(=O)Nc1c(C(N)=O)n[nH]c1C +Cc1ccc(NC(=O)C(c2ccccc2)n2cnnn2)c(O)c1 +CCCOc1ccc2cc(C(=O)NC(C)C)c(=O)oc2c1 +N#CC(C(=O)c1cccc(N2CCOC2=O)c1)c1nc2ccccc2[nH]1 +CCn1nnc(NC(=O)COc2ccc(OC)cc2)n1 +CCCOc1ccc(Cl)c2c1CCNC2C1CC(=O)C1 +COCCNC(=O)CN1CCN(C(=O)NC(C)c2ccccc2)CC1 +COc1ccc(N)cc1Oc1cccc(Cl)c1C#N +CC(C)(C)N1CC(c2nc(-c3ccc4nc[nH]c4c3)no2)CC1=O +CN1CCN(C(=O)NCc2ccc(O)cc2)C(c2ccccc2)C1 +CCCCN(C)S(=O)(=O)NC1c2ccccc2CC1O +CCOc1cc(NC(=O)Cc2ccc(OC)cc2)ccc1OC +CC(C)CCOc1cccc(C(=O)Nc2ccccc2C(N)=O)c1 +Cc1ccc(-n2cnc(C(=O)N3CCC(C)CC3)n2)cc1 +O=C(NC(c1ccccc1)c1ccccn1)c1cnns1 +CCC(Sc1ncc(CO)n1C)C(=O)c1ccc(Cl)cc1 +CCC(CC)N(C)C(=O)NCc1ccc(-n2cccn2)cc1 +c1cncc(-c2n[nH]c(SCc3cccc4c3OCCO4)n2)c1 +NC(=O)CCCOc1cccc(Br)c1 +CC(=O)Nc1ccc(C(=O)NC2CCCCCC2)cc1 +CN1CCN(C(=O)C2CCN(c3ccccc3)C2=O)CC1=O +Cc1nc(C(=O)N2CCN(C(C)c3ccccc3F)CC2)cs1 +CCCc1nc(NCc2noc(C3CCCO3)n2)c2cnn(C)c2n1 +COCCn1ccc2c(NC(=O)c3snnc3C)cccc21 +CC(C)NS(=O)(=O)c1ccc2c(c1)C(C)(C)CC(=O)N2 +CCc1nc(NC(=O)NCc2ccc(OC)cc2)nn1C +COCCCNc1nc(C)nc2sc(C)cc12 +COCC(C)NC(=O)NCc1ccc(Oc2cccnc2)c(F)c1 +N#Cc1ccc(N2CCCC(C(=O)Nc3nccs3)C2)nc1 +Cc1ccc(NC(=O)C2CCCOC2)cc1S(C)(=O)=O +COc1cccc(-c2noc(-c3ccc(-c4cc[nH]n4)nc3)n2)c1OC +N#Cc1ccc(NC(=O)CCSc2ccc3c(c2)OCCO3)cc1 +COc1ccccc1CCCNC(=O)C1CCC(=O)N1 +CCOc1cc(CCC(=O)N(C)Cc2cccc3ncccc23)on1 +CCOC(=O)c1c(NC(=O)c2nc[nH]n2)sc2ccccc12 +O=S(=O)(NCCCO)c1ccc2c(c1)OCO2 +CC(C)Oc1ccc(CNC(=O)c2cc(C(N)=O)cs2)cc1 +Cc1cc2oc(C(=O)NCc3ccncc3)c(C)c2cc1Cl +N#Cc1ccc(NC(=O)Cc2cccc(Cl)c2)cc1 +Cc1ccc(S(=O)(=O)Nc2ccc(S(C)(=O)=O)cc2)cc1 +C=CCNc1cc(S(=O)(=O)N(C)C)ccc1OC(C)C +Cc1ccc2ncc(C(=O)OCC3CCCCO3)c(=O)n2c1 +NC(=O)c1ccccc1NC(=O)c1csc(-c2cccs2)n1 +CCCc1cc(C(=O)N2CCN(C(=O)C3CCCCC3)CC2)n(C)n1 +Cc1cc(=O)n2c(-c3ccccc3)c(-c3ccco3)nc2n1C +CNC(=O)c1cnc(COc2ccccc2F)nc1N +CC(C)(C)OC(=O)N1CCC(c2nc(-c3ccc(F)cc3)n[nH]2)CC1 +O=C(NCc1cscn1)c1cc(=O)[nH]c2ccccc12 +Cn1c(SCC(=O)NC(C2CC2)C2CC2)n[nH]c1=O +COc1ccc(OC)c(C(O)CNC(=O)c2cc[nH]n2)c1 +Cc1c(Cl)cccc1NC(=O)C1CCCN1C(=O)C1CC1 +O=C(Nc1cnn(-c2ncncc2N2CCCC2)c1)c1ccccc1 +COCCC(Nc1cnc2cc(F)c(F)cc2n1)c1ccco1 +Cc1cc(O)c(C(=O)Nc2ccccc2)c(=O)n1Cc1cccnc1 +CS(=O)(=O)c1ccccc1NC(=O)CC1CCCCC1 +CC(C)Cn1c(-c2ccc3c(c2)OCCO3)ccc(N)c1=O +COCc1cccc(CNC(=O)c2cc(S(N)(=O)=O)c(C)o2)c1 +Cc1ccc(-n2nnnc2NCc2nncn2-c2ccccc2)cc1 +COc1ccc(CNc2sc(C)cc2C#N)cc1 +CCCC(=O)Nc1ccc(CNC(=O)c2cscn2)cc1 +Cc1[nH]cc(C(=O)NCc2ccnn2C)c(=O)c1Br +CCOc1ccccc1CNc1ccccc1C#N +O=C(NCC(O)C1CCCCC1)C1CC(=O)N(c2ccccc2)C1 +CCC(CC)NC(=O)C(C)Sc1nncn1C1CC1 +Cc1cc(Br)cc(C)c1NCC(=O)NCC1CC1 +CCN(CCO)C(=O)c1cc2ccc(Cl)cc2[nH]1 +CCC(C)n1nccc1NC(=O)c1ccc(OC(F)F)c(OC)c1 +C=CCOCc1cncc2c1CCN(Cc1cccs1)C2 +Cn1nnnc1SCC1NCCc2c(N)cc(F)cc21 +CC(NCc1cccc(C#N)c1)C(=O)Nc1ccccc1 +CC(=O)NCCNC(=O)Nc1ccc(CC(=O)NC(C)C)cc1 +CCn1cc(C#N)c(=O)n(CCCOc2cccc3ccccc23)c1=O +NC(=O)Cc1csc(NC(=O)c2cccnc2SC(F)F)n1 +Cc1ccccc1OC(=O)COc1ccccc1F +COCCC1COC2(CCN(C(=O)c3cccc4ncccc34)C2)C1 +CC(=O)N1CCCC1C(=O)NCC1(c2cccc(F)c2)CCOCC1 +Cc1cc(CNC(=O)c2ccc(-n3ccnc3)cc2)c(C)o1 +COc1cccc(CN(C)C(=O)CN2CCOCC2CC(C)C)c1 +Cc1cc(C)nc(SCc2ccc(C(=O)Nc3nncs3)o2)n1 +Cc1nc(NC(=O)Cn2nc(-c3ccccc3)ccc2=O)sc1C +Cc1cc(C)nc(SCC(=O)NC2CCCc3ccccc32)n1 +CC(=O)Nc1ccc(CC(=O)NCC2COc3ccccc3O2)cc1 +Cc1nc(-c2ccccn2)sc1C(=O)NCc1ccc(F)cc1 +NS(=O)(=O)c1ncc(Br)cc1OC1CC1 +Cc1ccc(C(=O)NC2CCC(=O)CC2)cc1Cl +CCOC(=O)Cn1nc(C#N)cc1-c1ccc(C)cc1 +CCCC(O)c1ccc(OC)c(Br)c1 +COc1ccc(OCCN2CC(C(=O)O)C2=O)cc1 +CCN(CC)C(=O)CN1CCc2c1cccc2C(F)(F)F +CCNC(=O)c1ccc(C)c(NC(=O)C2CCOc3ccccc32)c1 +CC(=O)N1CCc2cc(CNC(=O)c3ccc(N(C)C)cc3)ccc21 +CC(C)c1cccc2c1NCC(c1cccs1)C2 +CCNC(=O)c1cc2c(OCC)cc3c(c2[nH]1)OC(C)C3 +Cc1ccoc1C(=O)N1CCC2(CCCN(CC3CCC3)C2=O)C1 +Cc1cc(F)ccc1S(=O)(=O)NC(C#N)c1ccco1 +COc1cc(C(=O)Nc2ccccc2SC)cc(OC)c1OC +CC(=O)Nc1cc(F)c(F)cc1NCC(=O)NC(C)c1ccccc1 +COC(=O)CNC(=O)C1CCN(C(=O)OCc2ccccc2)CC1 +CCOC(=O)N(C)c1ccc(NC(=O)CCn2cc(C)cn2)cc1 +CCNc1oc(C=Cc2ccc(OC)c(OC)c2)nc1C#N +CC(C(N)=O)N1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +COc1ccc(CCC(=O)Nc2cc(C)on2)cc1N +CCC(C)(C)NC(=O)C(C)Sc1nnc(C2CC2)n1C1CC1 +CC(Sc1ccccc1)C(=O)OCC(=O)N1CCCC1 +CCc1ccc(NCc2cc3cc(OC)c(OC)cc3[nH]c2=O)cc1 +CN1CCN(C(=O)c2sc3ccccc3c2Cl)CC1 +Cc1cc(NC(=O)c2c(F)c(F)c(F)c(F)c2F)no1 +Cn1c(CNc2cc(C#N)ccc2C(F)(F)F)nnc1C1CCC1 +CC(C)Nc1cccc(C(=O)NCC2CN3CCCC3CO2)c1 +COc1cc(NC(C)=O)ccc1NC(=O)c1ccco1 +CCc1nccn1-c1cccc(C2CCCN2C(C)=O)n1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)NCCCO +Cc1ccc(C(=O)CN2CCN(CCO)CC2)c(C)c1 +COC(=O)c1sccc1NC(=O)N1CCC(C)C1 +Cc1ccccc1CCNC(=O)Nc1cccnc1 +CCOc1cc(C#N)ccc1Oc1nccc(C(F)(F)F)n1 +CC(C)COC(=O)CSc1nnc(-c2ccccc2)c(=O)n1N +COc1ccc(SC(C(=O)NC2CC2)c2ccccc2)cc1 +c1ccc(-c2ccn3c(-c4cccnc4)nnc3n2)cc1 +Cc1ccc(NC(=O)c2ccc(=O)n(C)n2)cc1Cl +O=c1oc2cccnc2n1CCOc1ccc(OC(F)(F)F)cc1 +O=C(Cc1ccc[nH]1)NCc1ccc(-n2cnc3ccccc32)cc1 +Cc1ccc(-c2n[nH]c(C)c2NC(=O)Cc2ccc(F)cc2)o1 +CCOC(=O)C1CCN(C(CC)C(=O)c2ccc(N)cc2)CC1 +O=C(Nc1ccc(N2CCOCC2)cn1)C1COc2ccccc2O1 +CC1CN(C(C(=O)Nc2nncs2)C(C)C)CC(C)O1 +Cc1ccc2ncc(C(=O)N(CCC#N)Cc3ccccn3)n2c1 +Nc1nc2[nH]c(-c3ccc(Br)cc3)nc2c(=O)[nH]1 +COc1cccc(CC(=O)Nc2cc(OC)ccc2F)c1 +CC(=O)Nc1cccc(OCCNC(=O)NCc2nc(C)cs2)c1 +CNc1ccccc1C(=O)N1CCCCC1C(N)=O +CCC(C(=O)NCc1cnn(Cc2ccccc2)c1)n1cccn1 +CSc1ccc(C(=O)N2CCc3ccc(Cl)cc3C2)cn1 +Cc1ccc(N2CCC(NC(=O)C3CCCC3)C2=O)cc1 +Nc1nccnc1C(=O)N1CCc2c1cccc2C(F)(F)F +COC(=O)c1cc(NC(=O)c2cccc(C(F)(F)F)c2)c[nH]1 +Cc1ccc(C(=O)CNc2nccs2)cc1F +COc1cccc(C(=O)Nc2ccc(C(C)=O)c(C)c2)c1O +CN(CCNC(=O)c1ccc(-n2cccn2)nc1)C(=O)OC(C)(C)C +O=C(c1cccc(F)c1)N(Cc1ccco1)Cc1cccs1 +Cc1ccc(CN(C)C(=O)CSc2nc(N)cc(N)n2)cc1 +CCN(CC)C(=O)C1CC(c2cccs2)NS(=O)(=O)N1C +CC(=O)N1CCN(CCOc2ccccc2C)CC1 +CC1CCN(C(=O)c2ccc(Br)c(N)c2)CC1 +CCC(NC(=O)c1ccc(=O)[nH]c1)c1ccc(C)cc1 +Cc1ccc(NC(=O)CCc2c(C)c3ccc(O)cc3oc2=O)nc1 +O=C(CSc1nncs1)Nc1cccc2ccccc12 +COCc1nn2c(N)c(C#N)nnc2c1-c1ccc(OC)cc1 +CCc1c(C)[nH]c2c(-c3ccc(OC)c(OC)c3)c(C)nn2c1=O +Cc1ccc(NCc2noc(C3CC3)n2)cc1C(=O)NC(C)C +OCc1cnc(N2CCCC3CCCCC32)s1 +Cc1nc(COc2ccccc2C(=O)OCc2ccc(C#N)cc2)no1 +C=CCCCN(C)C(=O)c1cc(-c2ccccc2)nc2onc(C)c12 +Cc1ncc(C(C)NCc2ccnc(OCC(F)(F)F)c2)s1 +Cc1sc(=O)n(CCC(=O)NC(C(N)=O)C(C)(C)C)c1C +CCOC1CCCN(S(=O)(=O)c2ccccc2N)C1 +CCC(C)(C)C(=O)Nc1ccc(OC)cc1OC +CC(Oc1ccccc1-c1cccc(C#N)c1)C(N)=O +O=C(CC(F)(F)F)N1CCN(C(=O)C2CCCO2)CC1 +Cc1cccc2nc(C(=O)OCc3cnn(-c4ccccc4)c3)cn12 +CC(C)(C)C(C#N)NC(=O)Cc1ccc(OCC#N)cc1 +CC(c1ccc(F)cc1)N(C)C(=O)NCc1cccnc1 +O=C(NCCOc1ccccc1)C1CN(S(=O)(=O)C2CC2)C1 +COc1ccc(OC)c(CC(=O)NCc2c(C)cc(C)[nH]c2=O)c1 +CCn1c(-c2nccn2CCc2cccnc2)nc2ccccc21 +CCCCS(=O)(=O)NCC(=O)NC1CC2CCC1O2 +Cc1ccccc1OCCCn1cnc(C2CCC2)cc1=O +CCOc1cc(C#N)ccc1OCC(=O)Nc1cc(Cl)ccc1F +CC(=O)N(CC1CCCO1)C1(C(=O)NC2CCCC2)CCCCC1 +CC(C)n1cc(CCC(=O)NCCc2nccs2)c2ccccc21 +Cc1ccc(NC(=O)COc2nncc3ccccc23)cc1F +CC1CCCCC1NC(=O)CSc1nc(-c2cccnc2)n[nH]1 +CCCn1c(C)nnc1SCC(=O)N1CCCCCC1 +CCC1CCC(N(C(=O)CCC2CCCO2)C2CC2)CC1 +Cc1ccc(NC(=O)CC(C)(C)c2ccccc2)cc1C(N)=O +Cc1ccc(NCC(=O)N2CCCC(C)C2)cc1-n1nnnc1C +Cc1noc(C)c1CN(C)C(=O)NCCc1cnn(C)c1 +N#Cc1c(Cl)cc(C(=O)N2CCCC2)cc1Cl +CCN(CC)C(=O)c1cnc(-c2cccc(C)c2)nc1N +CCc1cc2c(c(C(O)c3ccco3)c1)NC(=O)CC2 +O=C(NCc1cn[nH]c1)c1cccc2cccnc12 +COc1ccc(C2CC(O)C(O)C2NC(=O)c2ccno2)cc1 +O=C(Nc1nncs1)N1CCCCC1c1cc2ccccc2[nH]1 +O=C(c1cscn1)N(Cc1ccc(F)cc1)C1CC1 +COC(=O)c1ccc(C)c(NC(=O)C(C)Sc2nccn2C)c1 +COCCOCC1NCCc2ccc(O)c(Cl)c21 +CCOc1ccc(CN(CC)C(=O)c2cc(F)cc(F)c2)cc1OC +Cc1cnc2n(c1=O)C(CC(=O)NCc1ccc(F)cc1)CS2 +CCOc1ccc(F)c(C(=O)NCc2ccc(OC)nc2)c1F +CCOC(=O)CNC(=O)Cc1csc(-c2cccc(C)c2)n1 +O=C(Nc1cccc(F)c1F)N1CCc2cc(F)ccc2C1 +Cc1ccccc1CC(=O)NC(C)C(=O)N=c1[nH]c2ccccc2[nH]1 +COc1cccc(OCc2noc3cc(OC(=O)N(C)C)ccc23)c1 +CCOC(=O)C(N)Cc1ccnn1Cc1ccccc1 +C=CCN(Cc1cccs1)S(=O)(=O)c1ccc(C)s1 +Cc1ccc(C(=O)NCc2ccc(Cn3ccccc3=O)cc2)c(O)c1 +CCC(C)CS(=O)(=O)c1ccc(COC)cc1 +CCCCSc1nnc(SCc2noc(C)n2)s1 +CNC(=O)Cn1nnc(CO)c1Cc1cccs1 +NC(=O)c1ccc(NC(=O)CCC2CCCCO2)cc1 +C=CCc1c(C)nn(C(=O)c2ccc(NC(=O)C3CC3)cc2)c1C +CCC(C)NC(=O)C1CC(=O)N(c2cnn(C(C)C)c2)C1 +CC1(C)C(=O)NCCN1C(=O)c1ccc(C(=O)c2ccccc2)cc1 +COc1c(F)ccc(C(=O)N(Cc2c(C)nn(C)c2C)C2CC2)c1F +CCCOc1ccc(C(C)NC(=O)c2cnc(C)cn2)cc1OC +CCOC1CCN(C(=O)c2ccc(N3CCNC3=O)cc2)CC1 +O=S(Cc1ccon1)c1nnc(NCC(F)(F)F)s1 +Cc1cc(-n2nc(C)c3cc(N)cnc32)nc2ccccc12 +O=C(OCC(=O)N1CCOCC1)C1CC1c1ccccc1F +Cc1ccc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)c(O)c1 +Cc1ccc(O)c(NC(=O)c2scnc2C2CC2)c1 +CCCCOC(=O)C1C2CCC(C2)N1C(=O)NCC +COc1cc2c(cc1CNC(=O)c1ccncc1Cl)OC(C)C2 +Cc1ccc(S(=O)(=O)N(CC(N)=O)CC(C)C)cc1F +COc1cccc(CNC(=O)NCC(C)CO)c1OC +CCN1c2ncc(CCO)cc2C(=O)N(C)c2cccnc21 +O=C(c1ccc(F)cc1)N1CCC2(CCN(c3cccnc3)C2=O)C1 +CCOC(=O)c1c(NC(=O)c2ccco2)sc(C)c1C +Cc1cc(C)nc(NC(=O)c2cccc(Cl)c2)c1 +CC(C)c1ccc(OC(=O)Cn2cnc3c(cnn3C)c2=O)cc1 +O=C1CC(c2cc(O)cc(O)c2)Oc2cc(O)cc(O)c21 +COC(=O)Cn1cc(NC(=O)c2c(C)oc(C)c2C)cn1 +COc1ccc(C(=O)OCC(=O)c2c[nH]c3ccccc23)cc1OC +Cc1noc(CCC(=O)N2CCN(c3cccc(F)c3C#N)CC2)n1 +CC(C)OC(=O)c1cn(-c2ccccc2)c(=O)c2ccccc12 +CC1CN(Cc2nc3c(F)cccc3[nH]2)CC(c2ccccc2)O1 +CCc1cccc(CC)c1NC(=O)NC1CCC2(CC1)OCCO2 +CNC(=O)NCC(=O)NCCCCc1nc(C)cs1 +CC(=O)c1cccc(NCc2ccc3c(c2)OCO3)c1 +COC(=O)CCC(=O)Nc1cccnc1Oc1cccc(C)c1C +Cc1ccc(CCNC(=O)NC(C)C(=O)N2CCCCC2)cc1 +Cc1nc2nc(-c3ccco3)nn2c(NCc2cccs2)c1C +Cc1cc(C)n2c(SCC(O)COc3ccccc3F)nnc2n1 +CC(CNC(=O)N1CCN(C(=O)N(C)C)CC1)N(C)c1ccccc1 +COC(=O)C1Cc2ncn(C(C)C)c2CN1C(C)=O +Cc1cccc2c1CCN2S(=O)(=O)c1c(C)n[nH]c1C +O=C(NCc1cn[nH]c1)c1cncc(Br)c1 +O=C(Nc1ccncc1)C1(c2ccc(F)cc2)CCOCC1 +CC(=O)NCCNC(=O)NC1(c2ccc(Br)cc2)CC1 +CC(C)OCC(=O)N1CCCC(N2CCNC2=O)C1 +CCCCNC(=O)c1ccc(Br)c(N)c1 +O=C(CCCNC(=O)c1ccco1)Nc1ccccc1F +O=C(NCCCn1ccc2cccnc21)c1cnn(-c2ccccc2)n1 +Nc1ccn(-c2ncc(C(F)(F)F)cc2Cl)c(=O)n1 +Cc1ccc(NC(=O)N(Cc2ccccn2)C2CC2)cc1 +Cc1occc1C(=O)N(Cc1ccco1)CC(F)(F)F +O=C(CNc1ccccc1Cl)NC1CCCC1 +Cc1cc(C)c(CNC(=O)NC(C)c2ccc(C)s2)c(=O)[nH]1 +CN(CC(=O)N1CCC2(CC1)OCCO2)c1ccc2ccccc2c1 +Nc1cc(C(=O)Nc2ccc3c(c2)OCCO3)ccc1F +CC(C)COc1cccc(CNC(=O)C2CC=CC2)c1 +Cc1ncc(CNC(=O)Nc2ccc3c(c2)CCC(=O)N3)s1 +COc1ccc(S(=O)(=O)N2CCC(Oc3cnccn3)CC2)cc1 +CCNC(=O)c1cccc(NC(=O)Cn2c(=O)ccc3ccccc32)c1 +COCC(=O)Nc1ccc(Oc2ccc(F)cc2)cn1 +Cn1ccnc(NC(=O)Cn2c(=O)n(C)c3ccccc32)c1=O +CCOC(=O)c1c(C2CC2)csc1NC(=O)c1ccccn1 +O=C(c1cc[nH]n1)N1CCCn2nnc(COCC3CC3)c2C1 +COc1c(C2CCCN2CC(O)c2ccc(F)cc2)c(C)nn1C +CCCNC(=O)COC(=O)c1n[nH]c(=O)c2ccccc12 +COC(=O)C1(N(C)C(=O)CCn2ccccc2=O)CCCCC1 +CN(CCCOc1cccc(Cl)c1)C(=O)Cc1ccon1 +COC(=O)Cc1csc(NC(=O)Cc2cccc(Cl)c2)n1 +NC(=O)c1ccsc1NC(=O)Cc1coc2cc3c(cc12)CCC3 +COc1ccccc1OCC(=O)NCc1nc(-c2ccccc2)no1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1ccc(F)c(F)c1 +O=C(c1cccc(-n2cccn2)c1)N1CCOC(CCO)C1 +CCOc1ncccc1-c1cc(C(=O)N2CCOCC2)ccn1 +CC(C)NC(=O)Nc1ccc(NC(=O)c2cc[nH]n2)cc1 +CC(C)CCN(C)C(=O)NCc1ccc(S(C)(=O)=O)cc1 +CN(Cc1cnn(C)c1)C(=O)C1(c2cccc(F)c2)CCCC1 +COc1cccc(-c2noc(N3CCc4ccccc4C3)n2)c1OC +CC(=O)c1ccc(NC(=O)c2nnn(-c3ccc(C)cc3)c2C)cc1C +Cc1nc(CN2CCCc3c(NC(=O)OC(C)(C)C)cccc32)no1 +O=S(=O)(Cc1ccc(Br)cc1)NC1CCCC1 +N#Cc1ccc(COc2cccc(NC(=O)C3CC3)c2)cc1 +CC(c1ccc(F)cc1F)N1CCCC(c2cc(C(N)=O)[nH]n2)C1 +COC(CNC(=O)CC(C)(C)C)c1ccsc1 +N#Cc1ccc(Nc2ccc3c(c2)OCCO3)c(F)c1 +CCC(CC)NC(=O)COc1ccc2c3c(c(=O)oc2c1)CCC3 +Cc1sc2ccccc2c1S(=O)(=O)NCc1cnn(C)c1 +CN(C(=O)c1ccncc1)C1(c2ccccc2Cl)CCCCC1=O +Cc1ccccc1C1(CNC(=O)Cc2ccc[nH]2)CCOCC1 +O=C(CCSc1ccccn1)Nc1ccc(NC(=O)C2CC2)nc1 +CN(CC(=O)NC1CC1)C(=O)c1ccc(F)cc1Br +COc1ccnc(NC(=O)c2ccc(Cn3cccn3)cc2)c1 +CC1(C(=O)NC2CCCCC2)Oc2ccc(Cl)cc2NC1=O +COc1cccc(NC(=O)N2CC(C)OC(C)C2)c1 +CC(O)(CCc1ccccc1)CNC(=O)c1cccc(F)c1 +N#Cc1cccc(NCC(=O)NCc2ccccc2)c1 +CN(CCO)c1ccc(-c2nc(-c3cccc(Cl)c3)no2)cn1 +CC(Sc1ncn[nH]1)C(=O)Nc1ccc(F)c(N)c1 +O=C(Cc1cccc(F)c1F)Nc1ccc2c(c1)C(=O)CCC2 +CC(C)c1cc(C(=O)NC(C)(C)C(N)=O)nn1C(C)(C)C +Cc1ccc(OC(=O)CCNC(=O)c2ccc(F)cc2F)c(C)c1 +CCCCNC(=O)Nc1ccc(N(C)C(C)=O)cc1 +CC(C)C(=O)NCCNC(=O)c1ccc(Cl)cc1N +O=C1CCN(c2ccccc2Cc2ccccc2)C1 +Cc1ccccc1CNC(=O)c1ccc2c(c1)NC(=O)CO2 +COc1ccc(OC)c(CN(C)C(=O)c2c(F)cccc2Cl)c1 +COc1ccc(Cl)cc1CNC(=O)c1cccc(C)n1 +COc1ccc(CC(C#N)C(=O)N2CCc3ccccc32)cc1 +CNC(=O)c1cccc(CN2CCCC(c3nc4ccccc4o3)C2)c1 +O=C(Nc1ccc2c(c1)C(=O)NCC2)c1cccc(C(F)(F)F)c1 +Cc1cc(NC(=O)N2CCC(c3ccnn3C)CC2)c2ncccc2c1 +C=C(C)COc1cccc(NCC(=O)N2CCCCC2)c1 +CNC(=O)NCC(=O)Nc1nnc(C(C)C)s1 +Cc1cccc(C(=O)N2CCCC2c2cc(C(C)C)on2)c1 +COC(=O)CC(C)C(=O)OCc1cccc(Br)c1C +Cc1cc(NC(=O)N2CCC3(CCC3)C2)c2ncccc2c1 +O=C(NCCCc1ccco1)c1ccc(-c2cc[nH]n2)cc1 +C#CCn1cc(CN(C)C(=O)c2cnn(C(C)CC)c2C2CC2)cn1 +COc1ccc(CC(=O)NC2CCCCC2)cc1OC +Cc1nc(N2CCOCC2)cc(N2CCN(C(=O)C(C)C)CC2)n1 +O=C(OCn1cc(F)c(=O)[nH]c1=O)Oc1ccccc1 +O=C(NCC(O)c1ccc2c(c1)CCO2)C1(c2ccc(F)cc2)CC1 +Cc1ccccc1CS(=O)(=O)NCC1CCC1 +COCC(c1ccnn1C)n1cc(-c2ccc(OC)nc2)nn1 +CCC(Oc1ccccc1OC)C(=O)Nc1ccccc1 +CN(C(=O)c1cccc(NS(C)(=O)=O)c1)c1ccccc1 +CC(C)NC(=O)N1CCN2C(=O)N(Cc3ccccn3)CC2C1 +Nc1ccc(Cl)c(NC(=O)c2ccc(F)c(F)c2F)c1 +CCc1nc(CC(=O)NCc2ccccc2)sc1C +CC(C)N(C(=O)Cn1nnc(-c2ccc(C(N)=O)cc2)n1)C(C)C +COc1cccc(OC)c1C(=O)N1CCOC(C(F)(F)F)C1 +N#Cc1nncn1CCOc1ccc(Cl)cc1Br +CC(=O)Nc1ccc(NC(=O)NCc2ccc(C)c(F)c2)cc1 +CC(NC(=O)c1ccc(-c2noc(C3CC3)n2)cc1)c1ccncn1 +Cc1cc(C)n(-c2ccc(NC(=O)c3cccnc3)cn2)n1 +CCc1n[nH]c(SC(C#N)Cc2ccc(C)cc2)n1 +COc1ccnc(N2CCc3nn(C(C)C)c(=O)cc3C2)n1 +CSc1nc2ccc(C)cc2c(=O)n1-c1cccnc1 +CS(=O)(=O)N1CCN(C(=O)c2c(F)cccc2Cl)CC1 +COc1ccc(CNC(=O)NCC(O)c2ccccc2Cl)cn1 +CCc1cc(=O)oc2cc(OCC(=O)N(C)CC(F)(F)F)ccc12 +O=C(NCc1ccc(-n2ccnc2)nc1)Nc1ccccc1 +CC(C)NC(=O)Nc1cccc(C(=O)N(C)CC(=O)N(C)C)c1 +CC(C)(C)c1ccc(CNC(=O)CCC2CCCO2)cc1 +Cc1cc(NC(=O)c2cnn(CC(C)C)c2C2CC2)n(C)n1 +COc1ccc(-n2ccc3c(c(C)nc4nc(C)nn43)c2=O)cc1 +CCN(Cc1ccncc1)C(=O)c1ccc2cnsc2c1 +CC(CO)(NC(=O)NCc1cn2ccsc2n1)C1CCCCC1 +O=C(Nc1nccs1)C1CCCN1C(=O)c1c[nH]nn1 +CCOC(=O)Nn1c(C)c(C(N)=O)c(C(=O)OC)c1C +COc1ccccc1Cn1ccc2nc3ccn(N)c(=O)c3cc2c1=O +Cc1cc(NC(=O)C2Cc3ccccc3O2)ccc1N1CCCC1=O +CCn1ncc(CNC(=O)c2cc(C)nc3onc(C)c23)c1C +COCCCNc1ncc(Br)c2c(N)cc(C)cc12 +CN(CCNC(=O)c1ccc2c(c1)NC(=O)CO2)c1ccccc1 +Cc1n[nH]c(C)c1NC(=O)c1cc(N)cn1C1CC1 +COC1CCCC1NS(=O)(=O)c1cn[nH]c1C +Nc1nc(-c2cc(Cl)c3c(c2)CCC(=O)N3)cs1 +CN(Cc1ccncc1)C(=O)NCC1(c2ccc3c(c2)OCO3)CC1 +CCNC(=O)Nc1ccccc1-n1cc(Br)cn1 +CC(C)n1c(N)nnc1SCc1cc(-c2ccccc2)no1 +Cc1cc(Br)ccc1Cn1nnnc1C +O=C(NCCc1cccc2cccnc12)Nc1cccnc1 +CN(C)C(=O)Cc1nc(CSc2cccc(Cl)c2)cs1 +COc1ccc(Cn2cc(C(=O)NCc3ccncc3)nn2)cc1 +N#CCCNC(=O)COc1ccc(Br)cc1 +C1=NC(CNc2nncc(-c3cccc4ccccc34)n2)N=C1 +CNC(=O)c1cccc(CN2CCNC(=O)CC2)c1 +COc1ccc(C(=O)NCc2ccncc2)c(OC)c1 +COc1ccc(NC(=O)c2coc(=O)c(Br)c2)cc1 +CC(C)S(=O)(=O)N1CCC(C(=O)NCC(F)(F)F)CC1 +O=C(Nc1cn[nH]c1)c1cccc(OCc2cn3ccccc3n2)c1 +CCOC(=O)c1cn[nH]c1-c1cccc(Br)c1 +O=C(COC(=O)C(O)(c1ccccc1)c1ccccc1)c1ccccc1 +C#CCN1C(=O)C(Cc2cc(C)ccc2C)Oc2cc(O)ccc21 +Nc1cc(Br)c2nc(-c3ccccc3)cn2c1 +Cc1nc(N2CCCC2C(=O)NC(C)(C)CO)nc2ccccc12 +C#CCNC(=O)NCCc1ccc(-n2cccn2)cc1 +Cc1nn(C)c(C)c1C(C)NC(=O)NCc1cccc(N(C)C)c1 +CCNC(=O)C1CCCN(C(=O)Nc2ccc(OCC)c(F)c2)C1 +CC1CCCN(S(=O)(=O)N2CCCC(C(=O)NCC3CC3)C2)C1 +CCOc1ccc(F)c(C(=O)OCc2cccc(C(N)=O)c2)c1F +N#Cc1ccsc1NC(=O)Cn1ccc2ccc(Cl)cc21 +COCCN(Cc1ccc2c(c1)OCO2)C(=O)CC1CCCC1 +CC(=O)Nc1cc(NC(=O)NC2CCc3cc(F)ccc32)ccc1F +Cc1cc(C(=O)NCCC2=CCCCC2)cc(S(N)(=O)=O)c1C +CC(C)Cn1nccc1NC(=O)Cn1c(=O)cnc2ccccc21 +Cc1nnc2n1CC(NC(=O)C1(c3ccccc3)CCC1)CC2 +NC(C(=O)NCc1ccncc1)c1ccc(O)cc1 +Cc1sc2nc(NCCO)n3nc(-c4ccco4)nc3c2c1C +Cc1cc(C(=O)NC(C)CC(=O)c2cccs2)c(C)o1 +Cc1ccc(CC(=O)Nc2sc3c(c2C#N)CCC3)cc1 +Cn1cc(C(=O)NCCCC(C)(C)CO)c(C(C)(C)C)n1 +NC(=O)C1CCN(C(=O)CCC(=O)c2ccc(F)cc2)CC1 +CC(NC(=O)COc1c(CO)cc(F)cc1CO)c1ccccc1 +CN(C)S(=O)(=O)c1ccc(F)c(NC(=O)CCC2CCCO2)c1 +N#CC(C(=O)CNC(=O)Cc1ccccc1)c1nc2ccccc2[nH]1 +Cc1ccc(S(=O)CC(=O)NC2CCCCC2)nc1 +CCOC(=O)c1nnsc1NC(=O)c1cccc2ncccc12 +CCOC(C)c1noc(CNc2ccc(Cl)cc2)n1 +CCS(=O)(=O)c1ccccc1C(=O)N(C)C1CCC(C)CC1 +CCOC(=O)c1[nH]c(C)c(C(=O)OCC(N)=O)c1C +c1nc(Sc2ccc3c(c2)OCCCO3)c2ccsc2n1 +Cc1nonc1OCCNc1ncnc2onc(C)c12 +COCCOc1ncccc1C(=O)OC1CCCC1 +CC1CN(C(=O)c2ccc(Cl)cc2N2CCCC2=O)CC(C)O1 +CN(CC(N)=O)C(=O)CCCOc1cccc(F)c1 +C#CCN(Cc1ccco1)C(=O)Nc1ccccc1Cl +CC1CCCCC1NS(=O)(=O)c1ccc2c(c1)CCN2 +Cc1nc(C(N)c2ccccc2)sc1C(=O)N(C)C +CCOC1CC1C(=O)Nc1ccc(Cc2nnc3ccccn23)cc1 +C=CCn1cnc2c1c(=O)n(CCOC)c(=O)n2-c1ccccc1 +CC1CC1CNC(=O)Cc1csc(N2CCCC2=O)n1 +COCCN(C)c1nc2nonc2nc1NCc1ccccc1 +CCOC(=O)c1cc(-c2ccc(OC)cc2)nc2onc(C)c12 +COc1ccccc1Nc1nc(N)nc(CSc2nccn2C)n1 +NC(=O)C1CN(C(=O)NCc2ccccc2)CCO1 +COc1ccc(CC(=O)NC(C)C(=O)N2CCNCC2)cc1 +Fc1ccc(CNc2c(-c3ccccn3)nc3cnccn23)cc1 +CCOc1ccc(-c2nccnc2C#N)cc1Cl +CC(NC(=O)c1ccc(-n2cncn2)cc1)c1ccc(F)c(F)c1 +O=S(=O)(NCc1ccc(F)cc1)c1ccccc1F +O=C(Nc1ccc2c(c1)COC2)N1CC=C(c2cccs2)CC1 +c1nc(NCc2ccc(CN3CCOCC3)cc2)c2sccc2n1 +CC(C)CCNC(=O)Nc1ccc(C(C)N2CCOCC2)cc1 +CCOC(=O)c1coc(NC(=O)NC(CC)CC)n1 +COC(=O)CCN(C(=O)Cn1cnc2c(cnn2C)c1=O)C(C)C +COCCCN(C)S(=O)(=O)c1cc(C)c(C)c(N)c1 +Cc1ccc(C(=O)N2CCOCC2)cc1NC(=O)c1cccc(F)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccc(-n2ccnc2)cc1 +CC1CCCCC1NC(=O)CSc1ccncc1 +Cc1ccc(CN(C)C(=O)Cn2c(=O)c(C#N)cn(C3CC3)c2=O)o1 +O=C(CCCn1ccc2cc(Cl)ccc21)NCCN1CCOCC1 +CCS(=O)(=O)NCc1nc(-c2ccccc2)no1 +NC(=O)c1ccc(NCCOc2ccc(F)cc2)cc1 +CC(C)(C)Oc1cc(CNC(=O)c2ccc3c(c2)OCCO3)ccn1 +CN(C)C(=O)c1ccc(-c2cccc(N(C)C)c2)nc1 +CCc1noc(CC)c1CC(=O)N(CC1CCCO1)C1CCCC1 +COc1cc(CNC(=O)c2ccccn2)ccc1OCc1cccnc1 +CSc1ccc(C(=O)N2CCNC(=O)CC2)cc1 +CCn1cc(C(=O)Nc2ccc(C)cc2)c2cccnc21 +CC(C)OC(=O)c1ccc(NC(=O)c2cc(N)ccn2)cc1 +CN(Cc1ccc(F)cc1F)C(=O)c1cc(=O)[nH]c2ccccc12 +O=C(Cc1cnn(-c2ccccc2)c1)N=c1[nH]nc(-c2ccccn2)[nH]1 +O=C(CC1CCCN1S(=O)(=O)N1CCCCC1)c1ccccc1 +Nc1ncccc1C1NCCc2c(F)cc(Cl)cc21 +CCOc1c(Cl)cc(C(=O)NC(C)(C)C(=O)OC)cc1OC +Cn1ncc2c1CCCC2NC(=O)COc1ccc(F)cc1Cl +CCc1nnsc1C(=O)N1CCn2c(C(N)=O)cnc2C1 +NC(=O)c1sc2nc(-c3cccs3)ccc2c1N +CCC(Sc1nc2ncccn2n1)C(=O)NCc1ccccc1 +Cc1ccc(C(=O)CN2CCc3ccccc32)s1 +Cc1cc(C)n2nc(CC(=O)N3CCCC(n4cncn4)C3)nc2n1 +Cc1cccc(-n2ncc3c(O)nc(SCC(N)=O)nc32)c1C +Cc1nc(C)c(C(=O)NCC2(Cc3ccccc3)CCC2)o1 +COc1ccc(C(=O)NC(C)c2c(C)nn(C)c2C)cc1 +COCC(O)c1cc(C)c2c(c1)C(NC(C)=O)CC(C)(C)O2 +CCC(C)NC(=O)C1CC(=O)N(C)C1c1cccnc1 +COc1cc(F)ccc1NCc1cccc(OC)c1OC +CCOc1cccc2c1CCC2NC(=O)c1sc(COC)nc1C +CC=CCOC(=O)C1CCCN(C(=O)c2cc(C)cc(C)c2)C1 +Cc1occc1C(=O)N1CCN(C2CC(C)OC2=O)CC1 +CCCCNS(=O)(=O)c1ccc2c3c(cccc13)C(=O)N2C +COc1ccc(Oc2ncccc2NC(=O)N2CCC(O)C2)cc1 +O=C(c1cc(C2CC2)n[nH]1)N1CCC(O)(c2ccc(F)cc2)CC1 +Clc1ccc(-c2nnc(Cn3nccc3-c3ccncc3)o2)cc1 +CC(=O)C(C)(C)OC(=O)Nc1nc2ccccc2s1 +Nc1cc(C(=O)Nc2cc(F)cc(F)c2)ccc1Cl +CCOc1ccc2cc(C(=O)Nc3cccc(CO)c3)[nH]c2c1 +COC(=O)c1c(C)c(C(=O)CN(C)C(C)=O)c(C)n1C +CCCC1CN(C(=O)C(OC)c2ccccc2)CCO1 +CC(C)n1ncnc1-c1ccc(-c2cc[nH]n2)cc1 +Cc1ccc(C(=O)N2CCC2)cc1S(=O)(=O)N1CCCCC1 +N#Cc1cccc(Cn2c(CO)nc3ccc(F)cc32)c1 +COc1cc(C)cc(CNC(=O)c2scnc2C2CC2)c1 +COc1ccc(C(C)Nc2ccc(C#N)cc2)cc1OC +COc1c(C(=O)N2CCN(C)CC2)nnn1Cc1ccccc1Cl +Cc1ccc(OCC(=O)C(C#N)c2nnc3n2CCCCC3)c(C)c1 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)Nc1nnc(C2CC2)s1 +CCCS(=O)(=O)NCCn1nc(-c2ccncc2)c2c1CCCC2 +CCn1cc(CN2CCN(Cc3cc(C)cc(C)c3)C(=O)C2)cn1 +COCc1nc(CNC(=O)c2cc(-c3ccccc3O)n[nH]2)no1 +CCNC(=O)c1cc(-c2cccc(OCCOC)c2)nc(N)n1 +O=C(Cn1cccn1)N1CCC(C(=O)N2CCCCCC2)C1 +CCCCNC(=O)C1CCCN(C(=O)Cn2cnnn2)C1 +CCOC(=O)N1CCC2(CC1)NC(N)=Nc1nc3ccccc3n12 +OCc1nnn(-c2nccs2)c1Cc1ccc(Cl)cc1 +Cc1ccc(C(=O)N(C(C)C)C2CCOCC2)c(C)c1 +Cc1csc(CNC(=O)NCC(O)COc2cccc(F)c2)n1 +COc1ccc(OC)c(C(=O)CNc2ccccc2C)c1 +O=C(NCC(=O)N1CCCC1)C1CC(=O)N(CC2CC2)C1 +CCc1onc(C)c1C1CCCN1C(=O)NCC1CCCO1 +O=C(Cn1c(=O)cnc2ccccc21)NCC1CCOC1 +CC(=O)N(C)CC(=O)NCC(C)c1c(Cl)cccc1Cl +CSc1nsc(NC(=O)Cc2ccc(OC(F)F)cc2)n1 +COc1ccc(C(=O)N2CCC(c3cc(N)on3)CC2)c(OC)c1 +O=C(c1ccsc1)N1Cc2ccnn2CC(COCC2CC2)C1 +Cn1cnc(CNC(=O)Nc2ccc(Br)cc2F)n1 +Cc1nc(C)c(C(C)Nc2cccc(O)c2)c(=O)[nH]1 +CC(=O)c1cccc(S(=O)(=O)Nc2cc(C)ccc2F)c1 +COc1ccc(C(O)CNc2ccccc2C#N)cc1N +O=C(NCC1CCCC1NC(=O)c1ccsc1)c1ccsc1 +Nc1cccc(C(=O)Nc2cc(Cl)ccc2Cl)c1 +N#Cc1nnn(-c2ccc(O)cc2)c1-c1cccc(Cl)c1 +Cc1ccc(C(=O)NCC(=O)Nc2ccn(C)n2)cc1 +C#CCNC(=O)c1ccccc1NC(=O)c1cc(CC)c(C)s1 +Cc1nc(Cc2nnc(SC(C)C(=O)NCC(C)C)o2)cs1 +CN(CCc1ccc(Cl)cc1Cl)C(=O)CC#N +CCSc1nnc(N)n1C(C)C(=O)NC1CCCCC1 +CC(C)(Cc1ccc(F)cc1)N1Cc2ncccc2C1=O +O=C(Nc1ccccc1-n1cncn1)c1cc(C2CC2)on1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1ccn(-c2ccccc2)n1 +CCOCC(=O)NCC1(O)CCOc2ccccc21 +CCCCNC(=O)C1CC(=O)N(c2n[nH]c3ccccc23)C1 +O=C1CCCN1CC(=O)N1CCCCC1c1nc2ccccc2s1 +CC1CCCCN1C(=O)NC1CCC2(CC1)OCCO2 +NC(=O)c1cnc(NCc2ccnc(-n3cccn3)c2)c(Cl)c1 +CCOc1ccc(C2=CCN(C(=O)c3ccc(C#N)cc3)CC2)cc1 +CCc1ccc(NC(=O)CCC(C)C)cc1S(N)(=O)=O +C(=CCSc1ccccn1)CSc1ccccn1 +Cc1cc(CO)nn1-c1cc(C(F)(F)F)ccc1Cl +CN(Cc1nc2ccccc2[nH]1)C(=O)c1ccc(N2CCCC2)nc1 +CCCc1cc(=O)[nH]c(Nc2nc(C)c(C(=O)OCC)s2)n1 +CCN1CCN(C(=O)c2c(C)oc3ncn(CC(C)C)c(=O)c23)CC1 +CCOc1ccc(CNc2oc(CC)nc2C#N)cc1OC +CS(=O)(=O)NCC1CCCCN1C(=O)c1ccccc1Cl +CC(NC(=O)NCc1cccc(S(N)(=O)=O)c1)C1CC1 +Cc1ccc2nnc(C#N)c(NCC(=O)N(C)C)c2c1 +CC(C)(C)OC(=O)N1CCC(C#N)(c2cccc(F)c2)CC1 +c1csc(N2CCN(Cc3nnc(C4CC4)o3)CC2)n1 +CCCCCCNC(=O)c1cc(=O)c2cc(F)cc(N)c2o1 +COCCN1CC(C(O)c2ccc(Cl)cc2)CC1=O +CN(CCn1cnc(-c2ccccc2)c1-c1ncc[nH]1)S(C)(=O)=O +CS(=O)c1ccccc1NC(=O)c1ccc(Cl)cn1 +O=C(NC(c1cccnc1)C(F)(F)F)c1cccc2ccnn12 +CC1Cc2ccccc2N1C(=O)c1ccc(=O)n(C)n1 +CCCN(CCC)C(=O)c1cc(N)cc(OC)c1OC +CCc1c(-c2nnc(SCC(N)=O)n2C(C)C)csc1C +CC(OCC(F)(F)F)C(=O)NCCN1CCOCC1 +CC1CN(CCCNC(=O)N(C)Cc2ccccn2)CC(C)O1 +COc1ccc(OC(=O)COc2ccc(C)cc2OC)cc1 +CCOc1ccc(Cc2nn3c(-c4cnccn4)nnc3s2)cc1 +O=C(NC1CC1)c1c(Br)cnn1C1CC1 +COc1ccc(-c2nc3cc(OC)c(OC)cc3n2CC#N)cc1 +CCc1noc(CC)c1CNC(=O)c1ccc(F)cc1Cl +CCCCC(NC(N)=O)C(=O)Nc1cnn(-c2ccccc2Cl)c1 +CCOc1ccc(OCC(=O)N2CCC(c3ccsc3)CC2)cc1 +Cc1ccc(C(=O)N2CCN(CC(=O)Nc3cccc(F)c3)CC2)o1 +Cc1cc(OC(F)F)ccc1NC(=O)NCCc1ccnn1C +CC1(Cc2ccc3c(c2)OCO3)CCCN(C(=O)Cn2ccnc2)C1 +Cc1cc(-c2nc(-c3cccc(N)c3)no2)c(C)o1 +CCN(CC)C(=O)c1cccnc1SC(F)F +CC(=O)NCc1ccc(C(=O)Nc2cc(C(C)C)c(O)cc2C)cc1 +CC(=O)Nc1ccc(NC(=O)c2ccc(C)nc2)c(C(F)(F)F)c1 +COc1ccc(SC(C)C(=O)NC2CC2)cc1 +CCC1CN(CCC(N)=O)c2cc(F)c(F)cc2N1 +CCOC(=O)c1nn(CC)c2c1CN(C(=O)c1ccccc1)CC2 +O=C(c1ccc2ncsc2c1)N1CCCC(O)(CO)C1 +CCn1c(C)cc(C(=O)N2CCC(CC(N)=O)CC2)c1C +COc1ccc(OC)c2c1CCNC2C=Cc1ccncc1 +CCCC1CCC(NC(=O)CN2CCCS2(=O)=O)CC1 +CCc1c(C)nn(CCNC(=O)c2cn[nH]n2)c1C +CS(=O)(=O)c1ccccc1NC(=O)c1ccnc(OC2CCC2)c1 +CC1CCCCC1CC(=O)N1CCN(CCO)CC1 +CCN(CC)C(=O)c1cc(N)cc(S(C)(=O)=O)c1 +CN(Cc1cccc(C(N)=O)c1)C(=O)c1ccc(-c2ccccc2)n1C +CC1COC2(CCN(C(=O)CCC(=O)c3cccs3)CC2)O1 +CCN(C)C(=O)c1cccc(OCc2cccc(C(=O)N(C)C)c2)c1 +CSc1nc2nnc(C(=O)Nc3cccc(Cl)c3)c(C)n2n1 +COc1ccc(C(N)=O)c(OCC(=O)NC(C)c2ccccc2C)c1 +COc1ccc(-n2ccc(C(=O)N3CCNC(=O)C3)n2)cc1 +O=C(c1cc(F)ccc1F)N1CCc2nncn2CC1 +Cc1cccnc1NC(=O)N1CCc2ccc(OC(F)F)cc2C1 +COC(=O)c1ccccc1Nc1ncnc(N(C)C)c1N +COc1ccc(F)cc1NC(=O)CC1CCOc2ccccc21 +CCOC(=O)C(C)N1CCc2cc(F)ccc2C1 +CS(=O)(=O)NCc1ccc(C(=O)Nc2cc(F)ccc2O)o1 +CC(C)COc1ccccc1CN(C)C(=O)C1CCCCO1 +c1cncc(NCc2ccc(-n3ccnc3)cc2)c1 +CCn1nnc2cc(C(=O)NCCNC(=O)C(C)C)ccc21 +CCCC(CCC)C(=O)Nc1nnc2n1CCCS2 +CN1CC(C(=O)N2CCN(CC(O)c3ccccc3)CC2)CC1=O +Cc1ccc2c(c1)N(CCC(=O)NCCN1CCOCC1)C(=O)CO2 +CC(C)COc1nc2c(c(=O)n(C)c(=O)n2C)n1C +COC(C)c1ccc(-c2ncc(C)c(N(C)C)n2)cc1 +NC(=O)c1cccnc1Oc1cc(Cl)ccc1N +O=c1n(CCCS(=O)(=O)c2ccccc2)nc2n1CCCC2 +CCCc1csc(NC(=O)CNC(=O)c2ccc(C)c(C)c2)n1 +CS(=O)(=O)c1cccc(NC(=O)CCc2ccc3c(c2)OCO3)c1 +O=C(c1cc2ccccc2o1)N1CCCCC1Cn1cccn1 +O=C(NCc1cccc(F)c1)c1cccc(Br)c1 +COc1ccc(NC(=O)c2c(-c3cccc(F)c3)noc2C)cc1 +CCCc1ccc(C(=O)CNC(=O)c2ccco2)cc1 +CCN(Cc1ccoc1)C(=O)Nc1ccc(C(=O)OC)cc1C +CCOC(=O)c1ccc(NC(=O)C(C)n2cccn2)cc1 +Fc1cccc(-c2nnn3c2COC(CNCc2nccs2)C3)c1 +NC(=O)C1CC(=O)N(C2C3CC4CC(C3)CC2C4)C1 +COC(=O)Nc1ccc(NC(=O)CCNc2ncccn2)cc1 +CNc1cncc(C2CCCN2C(=O)c2ccnn2C)n1 +CCOc1ccc(-n2ccc3c(cnc4ncnn43)c2=O)cc1 +O=C(NC(c1ccccc1)c1ccncc1)c1ccsc1 +COC(=O)CCC(=O)C(C#N)c1ccc(Cl)c(Cl)c1 +CC(C)COC1CCN(S(=O)(=O)CC2CCCCO2)CC1 +Cc1nc(-c2cc3cc4c5c(c3oc2=O)CCCN5CCC4)cs1 +Cc1noc(CCCC(=O)Nc2ccc(C(C)C)cc2)n1 +COc1ccc(CN(C(=O)c2cc(Cl)c[nH]2)C2CC2)cc1 +COCC(=O)N1CCCC(c2nnc(-c3cccs3)o2)C1 +Cc1noc(C)c1CSc1ccnc(-c2ccccc2)n1 +O=C(Nc1ncccn1)c1ccc(S(=O)(=O)N2CCOCC2)o1 +C#CCOC(=O)C1CC(=O)N(Cc2ccccn2)C1 +Cc1nc2ccccc2n1CCNC(=O)c1cnn(C)c1-n1cccc1 +CCc1cc(C(=O)N(C)CCOc2cc(C)cc(C)c2)cc(=O)[nH]1 +CC(C)OCCN1CCN(C(=O)c2c(F)cccc2Cl)CC1 +Cc1nc(C)c(C2NC(=O)c3ccccc3N2C)s1 +Cc1cc(NC(=O)c2ccc3c(c2)OCO3)nn1C +CNC(=O)Nc1cc(OC)c(OC)cc1Br +O=C(c1c(F)cccc1F)N1CCCC(c2n[nH]c3nccnc23)C1 +Cc1cc(C(=O)N2CC(C(=O)Nc3nccs3)C2)no1 +COc1ccc(CN2C(=O)C(CCO)Oc3ccccc32)cc1 +CCS(=O)(=O)NCC(=O)Nc1cc(F)ccc1OC +Cc1nn(C)c(C)c1NS(=O)(=O)c1ccc(Br)cc1 +CC(CO)C(C)NC(=O)Nc1cccc(Cn2ccccc2=O)c1 +CCNC(=O)C(C)NS(=O)(=O)c1ccc(C2CCCCC2)cc1 +CCc1ccc(NC(=O)NCc2cccc(Cn3ccnc3)c2)cc1 +O=C(CC1COC(=O)C1)NC1CCCN(c2ccccc2F)C1=O +COc1cccc(C(=O)Nc2ccc3c(c2)C(=O)NCCO3)c1OC +N#CCn1c(=O)n(-c2ccc(Cl)cc2)c(=O)c2sccc21 +COc1ccc(Cn2c(CNS(C)(=O)=O)nc3cccnc32)cc1 +CC(Br)(Br)C(F)(F)F +CCn1nc(C(C)C)cc1C(=O)N(C)Cc1nc(C)no1 +CCN1CC(C(=O)Oc2ccc(C(C)=O)cc2)CC1=O +Cc1ccc(N(C)S(=O)(=O)c2ccccc2Cl)cc1N +Cc1c(N)cccc1NC(=O)C(C)OCc1ccccc1 +NC(=O)C1(CNS(=O)(=O)c2cc(F)cc(F)c2)CCOCC1 +CCNC(=O)CNC(=O)Cc1cc(C(C)=O)ccc1OC +CCOC(CC)C(=O)Nc1ccc(-n2ncc(C#N)c2N)cc1 +Cc1cnc(CNC(=O)c2cc(-c3ccncc3)n[nH]2)cn1 +Fc1cc(F)cc(CN2CC(c3nc(-c4cnccn4)no3)C2)c1 +COC(=O)Nc1cccc(NCC(=O)Nc2cccc(C)c2C)c1 +COc1ccc(C(=O)NCC(c2cccn2C)N2CCOCC2)cc1 +COc1cccc(CNC(=O)Cn2ncc3ccc(Cl)cc32)c1 +CCCCn1nc(C(=O)N2CCCC(c3nc(C)no3)C2)ccc1=O +COCCn1cnnc1SC(C)c1c(F)cccc1F +N#Cc1ccccc1COC(=O)c1ccccc1O +CC(C(=O)Nc1ccc2c(c1)COC2=O)N1Cc2ccccc2C1=O +CCNC(=O)CNS(=O)(=O)c1ccc(Cl)c(N)c1 +CCCCS(=O)(=O)Nc1ccc2oc(C)c(C(C)=O)c2c1 +C=CCn1c(N)nnc1SCC(=O)N1CCCc2ccccc21 +CC(CO)NC(=O)CC(c1ccccc1)c1ccccc1 +CC1CN(CC(=O)N2CCCC2)c2cc(N)ccc2O1 +Cc1nc(-c2ccncc2)[nH]c(=O)c1CCC(=O)NCCC(C)(C)C +Cc1ccn2cc(CNC(=O)c3ccc(Cl)cc3)nc2c1 +CCCc1cc(C(=O)N(C)C(C)c2ccccc2OC)[nH]n1 +O=C(c1ccoc1)N1CCCN(c2ccc(F)cc2)CC1 +Cc1cc(N)nc(SCc2nc3ccccc3n2C(F)F)n1 +CC(C)(C)c1ccc(C2(C(=O)C(C#N)c3ccccn3)CC2)cc1 +COCCOc1ccccc1NC(=O)c1cc(-c2ccccc2)[nH]n1 +CCc1noc(CC)c1CC(=O)NCCc1c(F)cccc1F +O=C(CCc1cccs1)NCCc1ccccc1 +Nc1nnnn1NCc1ccc(-c2ccc(F)c(Cl)c2)o1 +N#Cc1cccc(C(=O)NCc2ccccc2OCC(F)(F)F)c1 +Cc1csc(=O)n1CC(=O)N1CCCC1c1ccccc1Cl +CCN(C)c1ccnc(-c2ccnc3[nH]ccc23)n1 +N#Cc1ccccc1NCCC(O)c1ccc(F)c(F)c1 +Cc1nc2cc(S(C)(=O)=O)ccc2n1C1CC1 +Cc1ccc(S(=O)(=O)NCCn2cnc3ccccc32)cc1 +O=C(OCC(=O)N1CCc2ccccc21)c1cccc(-n2cnnn2)c1 +N#Cc1ccccc1N1CCCN(C(=O)NCc2cccs2)CC1 +CC(NC(=O)c1ccc(-n2cnnn2)cc1)c1cccs1 +CC(C)(C)n1nc(C(=O)OCCN2CCCC2=O)cc1C1CC1 +CCOC(=O)c1c(NC(=O)C2CCC2)sc(C)c1C +Cc1cc(F)ccc1CCNC(=O)CN(C)C(=O)c1ccccc1 +COc1cccc(N2CCN(C(=O)c3ccc4[nH]cnc4c3)CC2)c1 +C=CCNC(=O)c1ccccc1NC(=O)CN(C)c1ccccc1 +CC(=O)NC(C)(C)c1noc(C(C)Oc2ccc(Cl)cc2C)n1 +COCCN1CCN(S(C)(=O)=O)Cc2cccnc21 +CC1COc2c(Br)cc(N)cc2NC1=O +Cc1cncc(C2NCCc3c(O)cc(O)cc32)c1 +CCOC(=O)c1nc2sc(C)c(CC)n2c1N +N#Cc1cccc(-c2nnc(-c3nonc3N)o2)c1 +CC(C)CN(c1ccc(S(C)(=O)=O)cc1N)C(C)C +Cc1csc(NC(=O)c2nn(-c3ccccc3)c3c2CCC3)n1 +COCCNC(=O)C1CCCN(c2nc3ccccc3s2)C1 +Cc1ccc(-n2ccn3c(=O)[nH]nc3c2=O)cc1Cl +Cc1nnc(CNC(=O)c2cnn3c2OCCC3)o1 +Cc1n[nH]c(C(=O)NC2CCC3(CC2)OCCO3)c1Br +NC(=O)c1ccc2cc(Oc3ccccc3)ccc2n1 +COc1ccc(CCC(=O)NC(C)(C)C#N)cc1F +Cc1oc(NC(=O)C(C)N2CCOCC2)c(C#N)c1C +Cc1cccc(NCc2nnc3n2CCCCC3)c1 +Cc1n[nH]c(C(=O)NCc2cccc(F)c2)c1Br +Cc1cccc(C(=O)Nc2ccc(OCC(F)(F)F)nc2)n1 +Nc1cccc(C(=O)OCc2ccc(Cl)cc2)c1 +CC1C(=O)N(c2ccccc2)CCN1c1nc(N)nc2[nH]ncc12 +CCOc1ccccc1-c1noc(CCC(=O)Nc2cccnc2)n1 +COc1ncccc1NC(=O)N1CCCC1c1ccsc1 +CC1CN(C(=O)CCNC(=O)c2ccccc2Cl)CC(C)O1 +COCC(=O)NC(C(=O)NCc1ccc2c(c1)CCC2)C(C)C +CCn1nc(CC(C)C)cc1C(=O)N1CCNC(c2ccccc2)C1 +CC(C)c1cc(NC(=O)Cc2ccccc2F)[nH]n1 +CCC(C)NC(=O)c1csc(-c2ccccc2)n1 +Cc1nn(CC(C)C)c(C)c1CC(=O)NCc1nnc2ccccn12 +COc1ccc(OC(C)C(=O)Nc2cc(Cl)ccc2C(N)=O)cc1 +CCc1nc2c(=O)n(CC(=O)NC3CCCCC3)nc(C)c2s1 +CCCN(CCC)C(=O)c1cnc2[nH]nc(C)c2c1 +CCNC(=O)c1cccc(NCc2nc(C)cs2)c1 +Cc1cc2cc(C(=O)N(C)Cc3cc(-c4ccccc4)no3)ccc2o1 +Cn1cccc1C(=O)Nc1cc(F)ccc1Cl +Cc1cc(NC(=O)CC2C=CCC2)c2ncccc2c1 +C=CCn1c(C2CC(=O)N(Cc3cccs3)C2)nc2ccccc21 +O=c1cc(-c2ccccc2)nc(N2CCc3ccccc32)[nH]1 +CC(C)N(CC1CC1)c1cc(N)cc(S(N)(=O)=O)c1 +O=C(NC1CCN(C(=O)c2ccccn2)C1)c1ccncc1Cl +O=C(CN1CCOCC1C1CC1)NCCc1ccc(F)cc1 +Cc1cc(C)cc(NC(=O)Nc2nnc(-c3ccco3)o2)c1 +CC(=O)NCCNC(=O)Nc1cc(-c2ncco2)ccc1C +COc1ccc(C(C)Nc2ccc(C(N)=O)cc2)cc1OC +Cc1ccc(C2(O)CCN(c3cncc(C(N)=O)n3)CC2)nc1 +N#CCOc1cccc(CC(=O)NC2CCCOc3ccccc32)c1 +CC(=O)NCCCCCC(=O)N(C)c1ccc(C)cc1C +O=C(Nc1ccccc1)C1CC2CN(C(=O)NC3CCCC3)CC1O2 +Cc1nnsc1C(=O)N1Cc2cnc(CC(C)C)nc2C1 +CCOC(=O)CSc1ccc(NC(=O)C2CC2)nn1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2ccc(N(C)C)nc2)c1 +Cc1noc2ncnc(NCc3nc(-c4ccc(F)cc4)cs3)c12 +COc1ccc(CC(=O)c2c(O)cc(O)cc2O)cc1OC +CN1C(=O)CCC(C(=O)NCc2cccs2)C1c1ccccc1F +Cc1cccc(C(=O)N2CCCC(C(=O)NC3CCCCC3)C2)c1 +Cc1cc(C(=O)N2CCN(C(C)c3cccnc3)CC2)c(C)s1 +Clc1cccnc1-n1ccc(NCc2cncs2)n1 +COc1ccccc1C(C#N)NS(=O)(=O)c1cccs1 +Nc1ccc(-c2cn3c(C(=O)N4CCCC4)csc3n2)cc1 +Clc1ccc(Cn2cc(-n3cnnn3)cn2)c(Cl)c1 +Cc1nc(C2CCCN(C(=O)C(C)c3c(C)nn(C)c3C)C2)no1 +COc1ccc(NC(=O)N2CCCN(c3nc(C)cs3)CC2)cn1 +CCOC(=O)Cc1c(C(=O)OCC)[nH]c2c1C(=O)CCC2 +N#Cc1ccc(OCC(=O)NCCc2ccccc2)cc1F +CC(CCc1ccco1)NC(=O)Cc1ccc(N2CCCC2=O)cc1 +CCc1ccc(CNC(=O)COc2ccc(-n3cnnn3)cc2)s1 +Cn1cc(C(=O)COc2ccc(Br)cc2Cl)cn1 +CC(C)Oc1ncnc2c1CCN(S(=O)(=O)C1CC1)CC2 +O=S1(=O)CC(N2CCOCC2)c2ccccc21 +CC(Cn1cccn1)NC(=O)N(Cc1ccccn1)C1CC1 +O=C(Nc1ccc(F)cc1F)c1cc(-c2ccncc2)[nH]n1 +Cc1cc2oc(=O)cc(CN(C)Cc3ccccc3)c2cc1O +Cc1cccc(OCC(C)NC(=O)c2cc(C)on2)c1 +CCS(=O)(=O)c1ccc(C(=O)N2CCCC2Cn2cncn2)cc1 +O=C(C1CCCO1)N1CCCC(n2nnn(-c3ccccc3)c2=O)C1 +Cc1nc2nc(C)c(C(=O)Nc3ccc(C(C)C)cc3)cn2n1 +CC(CC(=O)NCCc1nc2ccccc2n1C(C)C)n1cccc1 +O=C(Nc1cccnc1-n1cccn1)C1CCN(C(=O)C2CC2)CC1 +c1cc(CN2CCOC3(CCC3)C2)cc(-c2ccncc2)c1 +CCCc1nc(-c2cnccn2)sc1C(C)(C)O +Cc1cnn(C(C)C(C)Nc2ncnc3[nH]ccc23)c1 +Cc1cc(NCc2csnn2)ccc1Br +CC(=O)c1cccc(OCC(=O)Nc2nc3ccc(F)cc3s2)c1 +O=C(OCCc1cccs1)C(c1ccccc1F)N1CCOCC1 +CC(=O)NC(C)(C)c1noc(C2Cc3ccccc3N2C(C)=O)n1 +Cc1cc(C(=O)N2CCCC2c2nc(C3CC3)no2)no1 +O=C(NC1CC1c1cccc(Cl)c1)c1ccnc(F)c1 +O=C(NCCc1ccccc1F)Nc1cccc(N2CCOC2=O)c1 +Cc1noc(C)c1CC(=O)NC(C)C1=CCCCC1 +C#Cc1cccc(NCc2cccc(C(N)=O)c2)c1 +CCCOc1cc(CNC(=O)c2ccn3ccnc3c2)ccn1 +Cn1c(SCCn2cccn2)nc2ccccc2c1=O +CC(C)CCNC(=O)c1cc2ccccc2[nH]c1=O +CCC1CCCCN1C(=O)CSc1nnnn1-c1ccc(C)cc1 +CC(=O)c1ccccc1NCC(=O)Nc1cc(F)ccc1F +CCc1ccc(NCC(=O)c2ccc(F)c(N)c2)cc1 +CNc1ncccc1C(=O)NCCS(=O)(=O)c1ccc(F)cc1 +CCC1CCC(NC(=O)c2ccc3c(=O)n(C)c(=O)n(C)c3n2)CC1 +NC(c1cccnc1)c1nccn1-c1ccccc1 +O=C(Nc1cccc(-n2ccnc2)c1)c1cccc(F)c1Cl +CC(=O)Nc1ccc(C(=O)Nc2ccc(NC(C)=O)cc2Cl)cc1 +N#Cc1ccccc1OCC(=O)N1CCN(c2ccc(O)cc2)CC1 +COC(C)C(=O)Nc1cccc(NC(=O)NCc2ncc[nH]2)c1 +CCOc1cc(C(=O)Nc2ccc(F)cc2F)ccc1OC +CC(C)n1cnnc1SCc1nccn1Cc1ccccc1 +COc1c(F)cc(NC(=O)CCc2c(C)nn(C)c2C)cc1F +Cc1ccc(CNC(=O)NCC(=O)NCc2cccc(C#N)c2)cc1 +Cc1cc(C(=O)NC(C)Cc2cccs2)c2c(=O)[nH]n(C)c2n1 +O=C(CSc1ccccc1Cl)N1CCCCC1 +O=C(Nc1ccc(N2CCCC2)nc1)c1ccc(-n2ccnn2)cc1 +CC(CO)NC(=O)c1cccnc1Nc1cccc(C(F)(F)F)c1 +CCCCc1ccc(NC(=O)C(NC(C)=O)C(C)C)cc1 +O=C(CCc1ccsc1)NCC1COc2ccccc2O1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(N2CCOCC2)nc1 +Cc1noc(C)c1CC(=O)N1CC(C)c2ccccc21 +CCNC(=O)C(C)Oc1c(N)cc(F)cc1Br +C=CCn1c(SC2CCCC2=O)nnc1-c1ccc(F)cc1 +NC(=O)c1n[nH]c2ccc(NC(=O)c3ccc4c(c3)CCC4)cc12 +CC=CCCNC(=O)Nc1cc(-c2ncco2)ccc1C +COC(=O)c1cccc(NC(=O)c2cccnc2SC)c1 +CCOCc1ccccc1CNC(=O)Nc1nnc(C(C)(C)C)s1 +O=C(NCCc1cccnc1)NCC(C1CCOC1)N1CCOCC1 +COC(=O)c1cc(CNC(=O)c2cccc(Cl)c2)ccc1OC +CC(C)(C)n1cc(CNCc2ccnc(OC3CCCC3)c2)cn1 +Cc1nc(-c2ccsc2)sc1C(=O)NCc1ccoc1 +COc1ccc(-c2noc(CNC(=O)C3CC3)n2)cc1 +COc1ccc(C(=O)NC2(C#N)CCCCC2)cc1 +CN(c1cccc(N)c1)S(=O)(=O)c1cccc(Cl)c1 +CC(C)CNc1nnc(S(=O)(=O)CC(=O)NC2CCCC2)s1 +COC(=O)C1CC(NC(=O)c2ccc(-n3cnnn3)cc2O)CN1C +NC(=O)CNC(=O)c1csc(-c2cccc(C(F)(F)F)c2)n1 +COc1ccc(OCc2nc(C(=O)N(C)C3COCC3O)co2)cc1 +Oc1cc(F)c2c(c1)C(Cc1c(F)cccc1F)NCC2 +CC1CCCC(OCC(=O)Nc2cnn(Cc3ccccn3)c2)C1 +Fc1ccc(OCc2nc(-c3ccccn3)no2)cc1F +O=C(NCc1ccco1)c1nc(-c2ccc3[nH]ccc3c2)no1 +CCCOC(=O)C(C)Sc1ccc(S(C)(=O)=O)cc1 +CCCOc1ccc(OCC(=O)NC(C)(C)C)cc1 +O=C(Nc1cccc(N2CCCCC2)c1)NC1CC1 +O=C(c1ccc2c(c1)OCO2)N1CCCCCC1c1ccco1 +Cn1cc(C(=O)N(Cc2ccccc2)CC2CCCO2)cn1 +COCc1ccccc1CNS(=O)(=O)c1cc(Cl)ccc1C +NC(=O)c1cc2c([nH]c1=O)CCCC2NC(=O)c1cccs1 +Nc1cc(CCOc2ccccc2Cl)nn1CCO +Cc1nc(N2CCC(C)(O)C(O)C2)nc2c1CCCC2 +Cc1nc2ccccc2n1CCNC(=O)N1CCOCC1 +Cc1ccc(NC(=O)c2ccc(C(N)=O)cc2)cc1C(F)(F)F +Cc1ccn2c(CN3CCOCC34CCC4)cnc2c1 +Cc1cccc(C(=O)N2CCC(NC(=O)C3CCCCC3)CC2)c1 +Cc1ccccc1CN(C)C(=O)c1ccn(C)c(=O)c1 +O=C(NCC(=O)N1CCc2ccc(Cl)cc2C1)c1cccc(F)c1 +COc1ccc(OCC(=O)Nc2ccc3c(c2)OCCCO3)cc1 +COc1cccc(CNC(=O)NC2(C)Cc3ccccc3C2)n1 +O=C(CN1CCN(c2ccc3nncn3n2)CC1)Nc1cccnc1 +COc1ccc(C(=O)Nc2cc(C(=O)NC3CC3)ccc2C)nn1 +COc1ccc(OC(C)C(=O)Oc2ccccc2F)cc1 +CCCCC(=O)N1CCCC(=O)c2ccc(C(F)(F)F)cc21 +CC(C(=O)NCc1cc(-c2ccco2)on1)n1cnc2ccccc21 +COC(=O)N1CCC(NC(=O)N(Cc2cccc(F)c2)C2CC2)CC1 +O=C(NCC(=O)N1CCCC1)c1cccc(-c2cn[nH]c2)c1 +Cc1ccc(OCC(C)NC(=O)CNC(=O)C2CC2)cc1 +CC(C)n1c(N(C)Cc2ccccc2)nc2c1c(=O)[nH]c(=O)n2C +COCCN1CCN(C(=O)NC(C)c2c(C)noc2C)CC1=O +Cc1cnc(-n2cnnc2)c(-c2ccc(S(C)(=O)=O)cc2)c1 +COCCn1cc(NC(=O)c2ccccc2NC(=O)C(C)(C)C)cn1 +C=CCn1nnc(NC(=O)c2cc(OC)c(OC)c(OC)c2)n1 +Cc1ccc(-n2cc(C(=O)Nc3nccn(C)c3=O)nn2)cc1 +Cc1cc(C(=O)OCC(=O)NC2CC2)c2ccccc2n1 +O=C(CCCn1cncn1)N1CCCc2cc(F)c(F)cc21 +COc1cccc(C(=O)CCCC(=O)N2CCCCC2)c1 +CC(C)S(=O)(=O)NCCn1ccc(C(F)(F)F)n1 +Cc1cc(=O)oc2c(C)c(OC3CCCCC3=O)ccc12 +CCc1nc(CCNC(=O)c2cc3c([nH]c2=O)CCCC3)cs1 +Cc1nonc1NC(=O)CN1CCOc2ccc(Cl)cc21 +CCN(CC(F)(F)F)S(=O)(=O)c1ccc(F)c(NC(C)=O)c1 +CC(=O)Nc1ccc(C(=O)OCC(=O)NC(C)(C)C)cc1 +Cc1ccc(NC(=O)Nc2ccc(CN3CCOCC3)cc2)cc1F +CC(NC(=O)c1c(F)ccc2cn(C)nc12)c1ccccc1 +CC(=O)Nc1ccc(CC(=O)NCCCn2ccc3ccccc32)cc1 +CSc1ccc(Cl)c(C(=O)NC(C)Cn2ccnc2)c1 +CCNC(=O)c1ccc(NCc2noc(CC)n2)c(C)c1 +CC(=O)N1CCN(c2ccccc2NC(=O)c2ccco2)CC1 +O=C(CCSc1ccccn1)Nc1ccc(-n2cncn2)c(F)c1 +Cc1c(NC2CCOCC2)cccc1S(N)(=O)=O +CCOC1CCC2C1OCCN2C(=O)c1cnccn1 +CC(=O)c1cc(C(=O)NCC2COc3ccccc3C2)c(=O)[nH]c1C +CCOC(=O)c1cnn(CCC(C)C)c1C(F)F +Cc1ccc(C(=O)N2Cc3cnc(CC(C)C)nc3C2)cc1Cl +O=C(NCc1cccnc1)N1CCCC1C1CCCCC1 +Cc1cc(-c2cncnc2C2CCCN(C(=O)C(C)(C)C)C2)on1 +Fc1ccc(C2NCCc3cc(F)cc(Cl)c32)nc1 +COc1ccc(NC(C)=O)c(NCC(=O)Nc2ccc(F)cc2F)c1 +CCOCC1CCC2C(CCN2C(=O)c2cnc(C)cn2)O1 +Cc1occc1C(=O)NCC(C)(C)c1ccncc1 +Cc1cccc(C)c1NC(=O)CN(C)C(=O)c1c(F)cccc1F +CCCCc1nc(C)sc1C(=O)N1CCC(CC(=O)OC)CC1 +CC1CC(C)CN(C(=O)Cc2nc3cc(N)ccc3o2)C1 +CN1CC(NC(=O)c2ccc3ccccc3n2)CCC1=O +O=S(=O)(CCCOc1ccc(F)cc1)N1CCCCCC1 +CC1CCCCC1NC(=O)C1CCN(C(=O)c2cccs2)CC1 +CCN(C(=O)Nc1cccc(NC(=O)C(C)OC)c1)C(C)C(C)C +Cc1cc(C(=O)NC2CCc3c(O)cccc32)on1 +CC(C)NC(=O)CN1CCN(S(=O)(=O)c2cnn(C)c2)CC1 +CCn1cc(NC(=O)NCC2(c3ccccc3F)CC2)ccc1=O +CC(=O)N1CCCCC1C(=O)Nc1ccncc1F +N#Cc1cc(NCC(=O)NC2CCCCC2)ccc1F +Cc1cn2c3c(=O)[nH]c(=O)n(C)c3nc2n1C(C)C +Cc1oc(-c2cccs2)nc1CC(=O)NC(C)CN1CCOCC1 +Cc1ccc(C(C)NC(=O)C2CCCN2C(=O)c2ccco2)cc1F +COCC(=O)NC(C)C(=O)Nc1nc2c(s1)CCC2 +O=C(c1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1 +CCC(NCC(C)C#N)c1ccc(OC)c(OC)c1 +CN1C(=O)CC(C(=O)NCC(=O)C(C)(C)C)C1c1cccc(F)c1 +Cc1c(C(=O)NCCCC(N)=O)cnn1-c1cccc(Cl)c1 +Cc1ccsc1CNC(=O)NCCc1ccc2c(c1)OCO2 +COc1ccc(NC(=O)C(C)Oc2cccc(N)c2)cc1Cl +COc1cccc(C(=O)Nc2ccc(Br)cc2O)c1F +O=C(NCCC(=O)N1CCN(c2ccccc2)CC1)c1ccco1 +COc1ccc(C(=O)OC(C)C(=O)c2[nH]c(C)c(C(C)=O)c2C)cn1 +CNc1ncnc2c1c(C)nn2-c1ccccc1F +COc1cc(Br)c(OC)c(C(=O)NCCNC(C)=O)c1 +COCCn1cc(C(=O)Nc2cc(C)n(C)n2)c2ccccc21 +CCCOc1cccc(C(=O)Nc2cccc(C(=O)N(C)C)c2)c1 +C=CCc1ccc(OCc2cccc(C(N)=O)c2)c(OC)c1 +Cc1n[nH]c2c1C(c1ccc(N(C)C)cc1)C(C(N)=O)=C(N)O2 +CC(Sc1ccccn1)C(=O)NCCCC(C)(C)C +Cc1ccn2c(=O)cc(COc3ccccc3)nc2c1 +CCC(=O)Nc1ccc(S(=O)(=O)N(C)C2CCCCC2)cc1 +Cc1cc(C(C)NC(=O)NC(C)CC(O)c2ccco2)c(C)o1 +Cc1cc(C)n2ncc(-c3noc(C(=O)NCc4cccnc4)n3)c2n1 +O=C(NCCCO)c1ccc(COc2ccc(F)cc2)o1 +CCOC(=O)C1=C(C)N(C)C(=O)N(C)C1c1ccc(O)cc1 +c1nc(C2CCCC2)sc1CN1CCOC2CCCCC21 +Cc1nc(NC(=O)N2CCC(C(O)C(C)C)CC2)nn1C +Cc1cccn2c(=O)c3cc(C#N)c(=O)n(C)c3nc12 +COc1ccc(CNC(=O)CNC(=O)Nc2ccccc2C)cc1 +O=C(NCc1cc[nH]n1)N1CCN(c2ccc(O)cc2)CC1 +COC(=O)C1CCN(C(=O)c2cc(C)on2)c2ccccc21 +N#Cc1nncn1Cc1cc(Cl)c2c(c1)OCO2 +CN(C)c1cccc(C2CCCN2S(=O)(=O)c2ccccc2)c1 +Cc1ccc(C(O)CNS(=O)(=O)c2cccs2)cc1C +CCOc1ccccc1NS(=O)(=O)c1ccc(C(C)=O)cc1 +Cc1occc1CN(C)C(=O)NC1CCCCC1 +O=C(NCCc1ccccn1)c1ccc(O)c(Cl)c1 +C#CCCOc1ccc(C2NC(=O)c3n[nH]c(C)c3N2)cc1 +CC(=O)NC(C(=O)Nc1nc(-c2cccnc2)cs1)C1CCCC1 +CC1CN(C(=O)c2cc(-c3ccccc3)nn2-c2ccccc2)CCO1 +COc1ccc(N(C)C(=O)C(C)(C)c2ccc3c(c2)OCCO3)cn1 +Cc1nnc2sc(NC(=O)c3ccc(OCC(C)C)cc3)nn12 +CCn1nc(NCc2cccc(F)c2F)cc1C +COc1ccc(SCc2nccn2CC(F)(F)F)cc1OC +COCc1nc(CN2CC(c3ccccc3)CC2=O)no1 +CCC(NC(=O)c1c(C)cc(C)cc1C)C(=O)N1CCOCC1 +CC(C)c1ncc(Cl)c(C(=O)NCCN2CCOCC2)n1 +Cc1nnc(Cc2ccc(Br)cc2)o1 +O=C(Nc1cccnc1)N1CCOCC(Oc2ccccc2)C1 +CN(C(=O)c1ccnc(-n2cncn2)c1)c1cccc2ncccc12 +CC(=O)c1ccc(OCC(=O)Nc2ccccc2)c(N)c1 +C=CCNC(=O)COc1ccc2c(C)cc(=O)oc2c1 +CC1CCN(c2cnnc3c(Cl)cccc23)CC1 +CCCC12CN(C(C)=O)CC(C)(CN(C(C)=O)C1)C2=O +CC(=O)Nc1cccc2c1ccn2CC(=O)Nc1nnc(C)s1 +COCCCn1c(SCc2cccc(C)c2)n[nH]c1=O +O=C(Nc1ccc2c(c1)OCO2)N(Cc1ccco1)CC1CCCO1 +O=C(Cn1nnc2ccccc2c1=O)Nc1cc(F)ccc1Cl +COC(=O)c1cccc2oc3cc(C)cc(O)c3c(=O)c12 +COc1ccccc1CNC(=O)C(C)Sc1nncs1 +COc1cccc(C(=O)Nc2sc3c(c2C(N)=O)CCCCC3)c1 +CCn1cc(C(=O)N2CCC(OCc3ccccc3C)CC2)cn1 +CC(=O)N1Cc2ccccc2CC1C(=O)Nc1ncc(C)s1 +Cc1nc(CN2CCOC(c3ccccc3Cl)C2)cs1 +COC(=O)C(C)(C)NC(=O)C1CN(Cc2ccccc2)CCO1 +Nc1cc(Cl)cnc1NCCCNC(=O)C1CC1 +O=C(NC1(C(=O)NCC2CC2)CCCC1)C1Cc2cccc(F)c2O1 +Cc1nc2cc(F)cc(C(=O)NCC(O)c3ccccc3)c2nc1C +NS(=O)(=O)CCNS(=O)(=O)c1ccc(O)cc1 +CCC(CC)(CO)NC(=O)COc1cccc(Br)c1 +O=C(c1cc(Cl)c2c(c1)OCCO2)N1CCC(c2cn[nH]c2)CC1 +COc1c2c(cc3c1OCO3)C(OC(C)=O)CN(C)C2 +CC1c2cccn2CCN1C(=O)c1ccc2c(c1)OCO2 +O=C(Nc1cc(Cl)cc2cccnc12)c1cc(Cl)ccn1 +CCC(CO)NC(=O)Cn1nnc(-c2ccsc2)n1 +CCn1nc(C)c(CNC(=O)Nc2ccccc2)c1C +Cn1cc(C(=O)NCc2ccc(S(C)=O)cc2)c(C(C)(C)C)n1 +CCOC(=O)CSc1nnc(N)n1Cc1ccc(Cl)cc1 +CN(CCC#N)S(=O)(=O)NCc1cnn(C)c1 +CCNS(=O)(=O)C1CCN(C(=O)c2cccc3cc[nH]c23)C1 +COCc1ccc(C(=O)Nc2ccc(OC)c(Cl)c2)cc1 +Cc1nc(N(C)C)ncc1C(=O)NCc1noc(-c2ccco2)n1 +Cn1cc(N2CC3(CCN(C(=O)C4CC4)C3)CC2=O)cn1 +Cc1n[nH]c(N2CCN(c3ccc(F)cc3)CC2)nc1=O +Cc1ncsc1C(=O)NC(C)Cc1ccco1 +CC(C)C(C)n1ncc(S(=O)(=O)NC2CCCC2)c1N +COc1ccccc1COC(=O)C(C)c1cccs1 +Cc1c(C(=O)Nc2ccccc2OC(F)F)oc2ccc(F)cc12 +CC(=O)Nc1cccc(NC(=O)c2ccc[nH]2)c1C +CC(NC(=O)NCC1(O)CCCCCC1)C(=O)N1CCCCC1C +Cn1cccc1C(O)CNC(=O)COc1ccccc1F +COc1ccc(CN(C)C(=O)c2ccccc2Cl)c(OC)c1 +Cc1ccc(CN(C)C(=O)c2cc(-c3cccc(Cl)c3)[nH]n2)o1 +CCOc1ccc(COc2ccccc2C(=O)NC)nc1 +Cc1ncc(CNC(=O)CCNS(=O)(=O)c2cccnc2)s1 +CNC(=O)COC(=O)C1CCCN1C(=O)c1cccs1 +Cc1ccc(OCC(=O)NCc2nncn2-c2ccccc2)cc1C +CC(C)NC(=O)Nc1ccc(C(=O)OC2CCOC2)cc1 +COc1cccc(C(=O)NCCC(=O)Nc2c(C)cccc2C)c1 +Cc1nn(CC(=O)N2CCCC2)c(=O)c2c1cnn2-c1ccccc1 +Cn1c(SCCO)nnc(Cc2ccccc2)c1=O +CNC(=O)CN(C)Cc1nc2sc3c(c2c(=O)[nH]1)CCC3 +COCCN(c1cccc(F)c1N)C(C)C1CC1 +COc1cc(C)nc(N2CCN(C(=O)Cc3ccc(C)nc3)CC2)n1 +CCc1ccc(N)cc1S(=O)(=O)N1CCCC(C)C1 +CCCNC(=O)c1ccc(CSc2ncn[nH]2)cc1 +COc1ccccc1C(C)N(C)C(=O)CNC(C)=O +COCCCN(C)C(=O)NC1CCCC(C)C1C +CC(Sc1nc2ccccc2s1)c1nc(C2CC2)no1 +Cn1ccnc1SC(C(=O)NC1CC1)c1ccccc1 +CNC(=O)Nc1ccc(NC(=O)c2ccc(C)c(C)c2)cc1 +CCN(CC)C(=O)C1CCCN(c2cc(C)nc3cc(C)nn23)C1 +CS(=O)(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +CCn1nc(C)c(C(C)NC(=O)c2ccn(C(F)F)n2)c1C +CCc1nnc(C(C)N2CCN(C(=O)Cc3ccccc3C)CC2)o1 +C=CCN(Cc1cccc(C#N)c1)CC(O)c1cccc(F)c1 +c1ccn2c(CNc3ncnc4sc5c(c34)CCCC5)nnc2c1 +COc1cc(C#N)ccc1OC(=O)CC1CC2CCC1C2 +CC(=O)Nc1ccc(F)c(C(=O)OC2CCCC(C)C2)c1 +N#CCCN(CC1CCOC1)S(=O)(=O)c1cc(F)c(F)cc1F +CC(C)(C)C(=O)Nc1cccc(-c2ccc(CO)o2)c1 +O=C(CC1COCCN1Cc1ccccn1)NCCN1CCNC1=O +NC(=O)c1cccc(CSc2nncn2C2CC2)c1 +O=S1(=O)CCCN1Cc1cc(F)ccc1Br +CCOC(C)c1nc(CN2CCN(c3ccccc3O)CC2)cs1 +COC(CNc1nccnc1C#N)c1cccc(Cl)c1 +CCCNC(=O)Cc1csc(Nc2cc(C)ccn2)n1 +CC(C)n1ccc(CCNC(=O)N2CCc3ccccc3C2CO)n1 +O=S(=O)(Nc1ccn(CCc2ccncc2)n1)c1ccc(F)cc1 +CCc1ccsc1C(=O)NCc1ccc(N2CCCCC2=O)cc1 +CCn1nc(C(=O)N2CCN(c3ccccc3F)CC2)ccc1=O +CCCOc1cccc(C(=O)Nc2ccccc2C(N)=O)c1 +CC(C)CN(C)C(=O)Nc1ccccc1Cn1cccn1 +Cn1c(=O)[nH]c2cc(C(=O)N3CCCS3(=O)=O)ccc21 +CC(=O)Nc1cccc(Nc2cc(C(F)(F)F)cnc2N)c1 +COc1cc2c(=O)cc[nH]c2cc1OCCCN1CCOCC1 +Cc1cccc(NC(=O)CCC(=O)Nc2nnc(C(C)C)s2)c1C +CSc1nc(N2CCOCC2)c2c(c1C#N)CC(C(C)C)OC2 +COCC(=O)N1CCCCCC1c1noc(-c2ccc(F)cc2)n1 +O=C(c1cn(Cc2ccccc2Cl)nn1)N1CCC(O)C1 +CC(CNc1nccc(-c2cccnc2)n1)Oc1cccnc1 +Nc1ccc2c(c1)C(c1[nH]c(=O)[nH]c(=O)c1F)NCC2 +O=C(NC1C2CCc3ccccc3C21)N1CCC(n2cccn2)CC1 +CC(=O)N1CCc2cc(C(=O)N3CCc4sccc4C3)ccc21 +CCOC(=O)C1=C(C)N(C)C(=O)NC1c1ccccc1OC +O=c1c2ccccc2cnn1Cc1ccccc1Cl +COCC(O)CN(C)C(=O)CNC(=O)c1cccs1 +Cc1cccc(NC(=O)NC2CN(c3ccccc3)C2=O)c1Cl +CN(C)C(=O)CN1C(=O)CCSc2ccccc21 +Cc1nnc2n1CCN(C(=O)c1ccnc(N(C)C)c1)C2 +Cc1ccc(C(O)C2NCCc3cc(O)ccc32)cc1 +CC(C)(C)OC(=O)NCCN1CCOCC1C1CC1 +CS(=O)c1ccc(C(=O)OCC2CCCCO2)cc1 +CC(C)(O)CCc1cccc(C(=O)N2CCC(C(N)=O)CC2)c1 +CCn1cc(N)cc1C(=O)NCCC1CCCCC1 +Cc1nc(NC(=O)c2cccc(OC(C)C)c2)sc1C(=O)N(C)C +Cc1ccc(NCC(=O)NC2CC2)cc1C(F)(F)F +CN(C)S(=O)(=O)c1ccc(O)c(NC(=O)c2ccco2)c1 +CN1CCSc2ccc(C(=O)Nc3cccc(F)c3)cc21 +CC(=O)c1cc(-c2ccccc2)n(CCC(=O)NC2CCCC2)c1C +COC(=O)C1(NC(=O)Cc2ccc(F)c(F)c2)CCCCC1 +CCc1cc(NC(=O)Cc2csc(-c3ccoc3)n2)[nH]n1 +Cc1cc(=O)oc(C)c1C(=O)OCCn1cccn1 +N#Cc1ccc(NC(=O)c2cccc(OCC(F)F)n2)nc1 +CN(Cc1cccnc1)C(=O)c1cccc(NC(=O)C2CC2)c1 +CCc1c(C(=O)Nc2ccnc(C)c2)[nH]c(C)c1C(C)=O +O=C(c1ccnc(OCC(F)F)c1)N1CCOCC1C1CC1 +Cn1c(=O)ccn(CC(=O)Nc2nc3c(s2)CCCC3)c1=O +c1cncc(CSc2nnnn2CC2CCCO2)c1 +NC(=O)N1CCCC(C(=O)Nc2cccc(Br)c2)C1 +Cc1n[nH]c(C)c1CCC(=O)NCc1ccc2ccccc2c1 +CSc1ccc(-c2nnn(CC(=O)Nc3ccccc3)n2)cc1 +Cc1ccc(-n2cnc3nc(N4CCOCC4)nc(=O)c-3n2)cc1 +CCn1c(=O)c2c(nc3n(CC(C)C)c(C)c(C)n23)n(C)c1=O +CC1Cc2ccccc2N1C(=O)c1ccc2snnc2c1 +O=C(Nc1ccc(Cl)cc1OCC(F)(F)F)c1ccncc1F +CCOC(=O)c1cc(-c2cc3cc(N)cc(OC)c3o2)n[nH]1 +N#Cc1ccccc1OC(C(=O)NC1CC1)c1ccccc1 +Nc1cc(C(=O)CCN2CCc3ccccc32)ccc1F +Cc1cc(Cl)ccc1OCCCC(=O)N1CCC(C(N)=O)CC1 +CC(c1ccco1)N(C)C(=O)Nc1cccc(NC(=O)C2CC2)c1 +Cc1ccc(OCC(C)NC(=O)c2ncoc2C2CCCO2)cc1 +CC(C)NC(=O)c1cccc(NC(=O)c2ccn3cncc3c2)c1 +N#CC(C1=NCCCC1)c1nnc2n1CCCCC2 +CCN(CC)C(=O)CSc1nc2cc3c(cc2cc1C#N)OCO3 +Cc1nc(NC(=O)c2cn(C)nc2C(C)(C)C)sc1SCC#N +CCC(=O)N(Cc1cc2cc(C)ccc2[nH]c1=O)C1CC1 +CCCC(=O)N1CCCC1C(=O)c1cc(OC)ccc1OC +CCOc1ccc(OCn2nnc3ccccc3c2=O)cc1 +Cn1nc2ccccc2c1C(=O)Nc1ccccc1F +CC1(C)Cc2nc(N3CCCCC3)c(C#N)cc2CO1 +COC(=O)c1ccc(C)c(NC(=O)CCC(=O)c2ccccc2)c1 +CC(=O)N1CCN(c2ncnc3scc(-c4ccccc4)c23)CC1 +CCn1c(SCC(=O)NC2CCCCC2)nc2ccccc2c1=O +CC1(C)CN(C(=O)Cc2ccc(F)c(Br)c2)CCO1 +CS(=O)(=O)n1c(CCc2ccccc2)nc2ccccc21 +CC1(C)CN(CC(F)(F)F)CCN1CC(=O)NCc1ccccc1 +COC(=O)c1sccc1NC(=O)Nc1ccc(F)cc1 +Cc1cc(C(F)(F)F)nn1CC(=O)N1CCCCC1C +Cc1ccc(CCS(=O)(=O)c2ccc(F)c(F)c2)cc1 +CC(=O)c1ccc(C)n(Cc2ccc(C)cc2)c1=O +CCCN(CCC)C(=O)c1cnn(-c2ccc(F)cc2)n1 +COc1ccc(C(O)Cc2cc(=O)cc(-c3ccccc3)[nH]2)cc1 +COc1ccc(C(C)=O)c(OCC(=O)Nc2ccccc2)c1 +O=c1c2c3c(sc2nc2ccc(N4CCOCC4)nn12)CCCC3 +CN(C)c1ccccc1-c1nc(N2CCCCC2)n(C)n1 +COc1ccc(C(=O)Nc2sccc2C(N)=O)cc1OC +CC(Sc1nncs1)C(=O)Nc1ccc(F)c(N)c1 +CCc1cc(C)c(C(=O)NC(COC)C(N)=O)o1 +CCCCn1c(=O)[nH]c(=O)c2c1nc(-c1ccccn1)n2C +CCc1ccc(C(=O)N2CCOc3ccc(F)cc32)o1 +Cc1nnc(CN2CCc3c2cccc3C(F)(F)F)o1 +O=C(NCc1cccnc1)c1c[nH]c2nc(-c3ccccc3)ccc12 +COc1ccc(CN(C)C(=O)c2ccn(C)c(=O)c2)cc1OC +C#CCCN1CCN(C(=O)C(NC(=O)OCC)C(C)C)CC1 +Cn1c(=O)nc2n(-c3cccc(Cl)c3)c3ccccc3cc-2c1=O +CCOc1ccccc1N1CCN(CC(=O)N2CCCCC2C)CC1 +O=C(NC(Cc1ccccc1)C(F)(F)F)N1CCN(CCO)CC1 +Cc1cccc(C(=O)Nc2ccnn2C(C)C)c1C +Cc1ccc(C(C)C)c(OCC(=O)N2CCNCC2)c1 +Cc1c(C(=O)OCCN2CCCC2=O)sc2ccc(F)cc12 +CC(C)c1nc2ccc(Br)cc2n1C +CC(c1cccnc1)N(C)C(=O)Nc1ccccc1N1CCOC1=O +Cn1c(C(=O)NCc2ccccc2Cl)nc2ccccc2c1=O +CC(=O)NCc1ccc(S(=O)(=O)NCc2ccc(C)s2)s1 +Cc1cc(CNC(=O)CCN2c3ccccc3CCC2C)no1 +COC1CC(OC(=O)C2CCCN2C(=O)OC(C)(C)C)C1 +N#Cc1ccc(NC(=O)c2ccccc2Br)cc1C#N +Cc1cccc2c1N(C(=O)CCc1c(C)nc(=O)[nH]c1C)CC2 +COc1ccccc1NC(=O)NC(C)C(C)CO +COC(=O)c1ccc(Cn2c(=O)oc3cccc(N)c32)cc1 +Cc1nn(-c2ccccc2)c(C)c1NC(C)C(=O)N1CCOCC1 +O=C(NCc1ccccn1)N1CCN(c2nccs2)CC1 +CCCC(=O)NCc1cccc(Cn2cnc3ccccc32)c1 +O=C(Nc1nnc(C2CCC2)s1)N1CCCCC1c1nccs1 +CCc1cc(C(=O)Nc2c3c(nn2C)CCC3)sc1C +O=C(Nc1cnc2ccccc2c1)c1cccc2ccoc12 +N#Cc1ccc(CN2CCN(c3ccccc3)CC2)c(F)c1 +O=C(NCCS(=O)c1ccccc1)NCC(F)(F)F +CC(CC1CCCCC1)C(=O)Nc1ccccc1C(N)=O +COc1ccccc1-c1nc2cc(F)c(F)cc2n1CCC#N +CC(C)CNC(=O)c1ccc(F)c(C(=O)N(C)C)c1 +Cc1csc(C2CC3CCN(C(=O)c4cc(C)on4)CC3O2)n1 +Nc1nc(-c2ccccn2)ccc1C(=O)NC1CCCC1 +O=C(Cn1c(-c2cccs2)cc2ccccc21)N1CCOCC1 +CCNC(=O)Nc1cc(NC(C)=O)c(OC)cc1OC +NC(=O)NCC1CCCN(C(=O)c2ccnc(-n3ccnc3)c2)C1 +O=C(CCC(=O)c1ccc(F)cc1)Nc1cccc2ncccc12 +CNc1nc2c(c(=O)n(C)c(=O)n2C2CCCCC2)n1C +O=C(NCCOc1cccnc1)c1cccc(NC(=O)C2CC2)c1 +CCn1cc(CNC(=O)Cc2c(C)[nH]c3c(C)ccc(C)c23)c(C)n1 +O=C1C2=Nc3cc(-c4ccccc4)nn3C(=O)C2CN1Cc1ccco1 +COc1cc(NC(=O)N(C)Cc2ccccn2)ccc1NC(C)=O +COc1cc(OC)c2c(=O)c(-c3ccc(OC)c(OC)c3)coc2c1 +COc1ccc(C(C)=O)cc1CC(=O)Nc1cc(F)c(OC)c(F)c1 +CCC(CC)N(CCOC)C(=O)C1CCN(C(C)=O)CC1 +O=C(C1CCC(n2cccc2)CC1)N1CCCC(n2cncn2)C1 +CC(NC(=O)c1cn2cccnc2n1)c1cccc(Cl)c1 +COC(=O)c1nnn(-c2ccc(OCC(C)C)cc2)c1N +O=C(CC1CCN(C(=O)c2ccc(F)nc2)CC1)N1CCCC1 +CCOc1ccccc1OCCN(C)C(=O)C1=NC(=O)N=C1 +COC(=O)C1CC(Oc2ccc(C)cc2Cl)CN1 +Cc1cc(C(=O)N2CCOC3CCCC32)c2ccc(F)cc2n1 +Cc1ccc2c(c1)N(CC(=O)Nc1ccccc1C)C(=O)CO2 +Cc1ccc(C)c(S(=O)(=O)NCCCOC2CCCC2)c1 +Fc1ccc(C2CN(c3cccc(F)n3)CCO2)cc1 +Cc1ccc2cc(OCc3nccs3)ccc2n1 +CC(=O)c1ccc(NC(=O)c2ccc(C)cc2)cc1 +N#Cc1ccc(CSc2nnc(N3CCOCC3)s2)cc1 +COc1cc(C(=O)NCc2ccccc2)ccc1OC(C)C +CCc1onc(C)c1NC(=O)c1cc(OC)ccn1 +Cc1nn2cc(C(=O)NCCCNC(=O)C(C)(C)C)nc2s1 +Cc1ccc(CC(=O)N2CCOCC2c2ncon2)cc1 +COc1cc2cnn(Cc3ccccc3)c2cc1OC +Cc1cc2c(=O)n(Cc3coc(-c4ccc(F)cc4)n3)cnc2s1 +NC(=O)c1ccc(Cl)c(NC(=O)C23CC4CC(CC(C4)C2)C3)c1 +Cc1cccc(C(=O)N(CCC#N)c2ccc3c(c2)OCCO3)c1C +Nc1ccccc1-c1nc2cc3c(cc2[nH]1)OCCO3 +Cn1cnc2cc(C(=O)N3CCOCC3C3CC3)ccc21 +COCCNc1nc(-c2cccc(OC)c2O)nc2ccccc12 +CC(=O)N(C)c1cccc(NC(=O)c2ccccc2)c1 +Cc1ccc(CCC(=O)C(C#N)c2nc(C)cs2)c(C)c1 +COC(=O)C1CCCCN1C(=O)c1ccc(OCC2CCCO2)cc1 +COc1ccc(N2CCCC(C(=O)Nc3ccc(Cl)cc3)C2)nn1 +COC(=O)c1ccc(Oc2ncnc(OC(C)C)c2N)cc1 +CC(CC(=O)NC(C)C(=O)N1CCOCC1)Cc1cccc(F)c1 +Cc1cc(NC(=O)CNc2cccc(N3CCOC3=O)c2C)n(C)n1 +CC(=CC(=O)OCCNc1cccnn1)c1ccccc1Cl +O=C(CC1CCc2ccccc21)N1CCN(c2cnccn2)CC1 +COc1ccc(CS(=O)(=O)c2ccc(O)cc2)cc1F +Cc1ccc(O)c(NC(=O)c2cc(-c3ccccc3)no2)c1 +O=C(Nc1nc(-c2ccccc2Cl)cs1)c1ccnnc1 +CCNc1nnc(-c2cc(-c3ccccn3)oc2CC)s1 +CCc1ccc(C(=O)NCc2cccs2)s1 +Cc1nc(CSc2nnc(-c3ccccc3)o2)cs1 +Cc1c(C(=O)N(CCC#N)Cc2ccco2)cnn1-c1ccncc1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)N1CCC(C(N)=O)CC1)O2 +COC(=O)CCCN(C)C(=O)c1ccc(C)c(C)c1O +Cc1ccc(C(O)CCCC(=O)NCc2ccccn2)c(C)c1 +COC(C)C(=O)N1CCN(c2cccc(F)c2C#N)CC1 +C#CCNC(C(=O)OCC)c1cccc(Cl)c1Cl +O=C1CCC(C(=O)N2CCC(c3nnc(-c4ccoc4)o3)CC2)N1 +Cc1ccc(C)c(-c2cncc(C(=O)NCc3ccncc3)c2)c1 +Cn1cnnc1C1CCCN(Cc2ccccc2OC(F)(F)F)C1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)NCCc1ccccn1 +CC(C)CC(CCO)CNC(=O)N1CCN(C(=O)C(C)(C)C)CC1 +CCc1cccc(C)c1NC(=O)CSc1ccccc1O +Cc1cccc(Nc2ccccc2C(=O)NCCO)c1C +c1nc2c3c4c(sc3nc(NCC3CCCO3)n2n1)CCC4 +CCOc1ccccc1N(CC(=O)NC(C)(C)C)S(C)(=O)=O +Cc1nc(-c2cccc(F)c2)nc2c1CC(=O)N2CC(C)C +N#Cc1cccc(C(=O)N2CCc3ncncc3C2)c1 +O=c1c2ccccc2oc2nc(-c3cccnc3)ccc12 +Cc1n[nH]c(C)c1Sc1ccccc1NC(=O)c1cccnn1 +CN(Cc1ncnn1C)C(=O)NC(c1ccccc1F)C1CCCC1 +Cc1nc(-c2ccccc2)ccc1C(=O)NC1CCc2[nH]ncc2C1 +COC(=O)Cc1csc(-c2cc(OC)ccc2OC)n1 +CCn1c(SCC2CCOCO2)nnc1N1CCOCC1 +CCOC(=O)CN(C)C(=O)CN1C(C)COCC1C +CCCn1nnnc1Cn1nc2ccccn2c1=O +Cc1ccc(C(=O)Nc2cnc3c(c2)c(C)nn3C)c(C)c1 +O=C1N(CCO)c2ccc(F)cc2NC12CCCCC2 +COc1cccc2cc(C(=O)NC3CC4CCC3C4)oc12 +COCCC1NCCc2c(F)cc(Br)cc21 +CC(C)CN(C(=O)C1CCN(c2ccc3nncn3n2)CC1)C1CC1 +O=C(c1coc(-c2ccccc2)n1)N1CCc2cc(F)ccc2C1 +CN(CCc1ccc(Cl)c(Cl)c1)C(=O)CO +Cc1ccc(C(=O)Nc2ccc(N3CCCC3=O)cc2)cc1 +NC(=O)C1CCN(C(=O)c2ccc3c(c2)Cc2ccccc2-3)C1 +O=S(=O)(Nc1ccc(F)cc1F)c1ccc2c(c1)CCC2 +CC(NC(N)=O)C(=O)N(C)CCCCc1ccccc1 +CCOC(=O)C1=C(C)NC(=O)NC1c1cccc(OC)c1 +COC(=O)CN(Cc1cccc(-c2ccncc2)c1)C1CCCC1 +C#CCNC(=O)c1cc(C)nc2c1cnn2Cc1cccs1 +Cc1nc(C(=O)N2CCC(O)(C3CCOCC3)C(C)C2)cs1 +N#Cc1ccc(-c2noc(Cc3c[nH]c4ncccc34)n2)nc1 +COc1ccc(Cl)cc1C(C)C(C#N)N1CCCC1 +CNC(=O)CCNC(=O)c1cc(Br)cnc1NC +CC(C)N(Cc1cc2ccccc2[nH]c1=O)C(=O)c1ccccn1 +Cc1cc(C(=O)CCC(=O)Nc2ccc(F)c(F)c2)c(C)s1 +C#CCNC(=O)NCc1ccc(OC)c(OC)c1OC +CC(=O)N1CCC(C)Sc2ccc(C(F)(F)F)cc21 +NC(=O)N1CCCC(C(=O)NCc2cn3cc(Cl)ccc3n2)C1 +CCCCNC(=O)Nc1cccc(NC(=O)CCC)c1 +Cc1ccc(CC(=O)OCc2ccc(-n3cccn3)cc2)cn1 +Cc1nn(CC(=O)OC2CCCCC2)c(=O)c2cc3occc3n12 +Cc1ccc2c(c1)-c1onc(C(=O)NCCc3ccsc3)c1CO2 +O=C(CSc1cccs1)OCC(=O)N1CCc2ccccc21 +COCCCN(Cc1ccncc1)C(=O)c1ccc(C)nc1 +COCCCOc1ccccc1NC(=O)c1cc(C)nn1C +Cc1sc(C(=O)NCC(=O)N(C)C)cc1-c1ccc(F)cc1 +COc1ncc(NC(=O)Nc2ccc(C)c(F)c2)c(N(C)C)n1 +N#CCCn1c(CCOc2ccccc2)nc2ccccc21 +CC(=O)NC(CC(=O)N1CCCC1C(N)=O)c1ccc(Cl)cc1 +CCCn1nc(C(=O)Nc2ccccc2CC)ccc1=O +Cc1ccc(C(=O)NCC(=O)Nc2ccccc2C)o1 +CCC(C)(C)C(=O)NCCc1ccc(NC(C)=O)cc1 +Cc1ccc(C)c(N(C(C)C(=O)Nc2cccnc2)S(C)(=O)=O)c1 +COc1ccc(-c2nn(CC#N)c3c2CNCC3)cc1OC +CCN(c1ccc(C)cc1C)S(=O)(=O)c1cnn(C)c1 +O=C(CCC(=O)N1CCOCC1C1CC1)c1ccc2c(c1)CCC2 +COc1ccc(CCC(=O)Nc2ccc3[nH]c(C)nc3c2)cc1OC +CC(C)(C)C(O)CCNC(=O)Cc1ccc(F)cc1 +Cc1ncnc(C)c1C1NCCc2c(O)ccc(Cl)c21 +COc1ccccc1OC(=O)CCc1cccc(F)c1 +Cc1nc(-c2cccc(OCC(=O)N3CCOCC3)c2)no1 +Cc1cnc(N2CCC3(CCCN3S(C)(=O)=O)C2)nc1 +CCc1ccc(NC(=O)NC2CCCn3nc(CC)nc32)cc1 +Cc1ccc(CCNC(=O)Cn2c(C)nc3onc(C)c3c2=O)cc1 +CC(NC(=O)Nc1cccc(F)c1)c1ccc2[nH]c(=O)[nH]c2c1 +COc1ccc(C(=O)Cn2c(-c3cccnc3)ccc(C#N)c2=O)cc1 +CC1(C(N)=O)CN(Cc2ccc3[nH]ccc3c2)CCO1 +N#CC1CN(Cc2ccc(Oc3cnccn3)cc2)CCO1 +Cc1nn(C)c(C)c1CC(=O)N1CCSc2ccc(Cl)cc21 +c1ccc(-c2ccc(CNc3ccon3)cc2)nc1 +COc1ccc(C(O)C(C)NC(=O)c2cccc(C#N)c2)cc1 +CCn1cnnc1C1CCN(C(=O)C2CC(=O)N(C3CC3)C2)CC1 +COc1cc(C#N)c(Br)cc1OC(C)C +CCn1nccc1CN(C)C(=O)Nc1cccc(Cl)c1Cl +OCCNc1ncnc2ccc(-n3ccc(-c4cccnc4)n3)cc12 +CC(C)(CNC(=O)NC1CCCC1(C)CO)c1ccncc1 +Cc1nn(C)c(C)c1C(C)NC(=O)c1ccccc1OC(C)C +COc1cc(OC)c(NC(=O)NC(C)c2ncc(C)s2)cc1F +COc1ccnc(N2CCOC(Cn3cc(C)cn3)C2)n1 +O=C(Nc1ccc(-n2cncn2)nc1)c1ccn(-c2ccccc2)n1 +CCNC(=O)CNC(=O)COc1ccc(Cl)cc1Cl +CCC(C)NC(=O)CN1CCN(C(=O)C2CC(=O)N(C)C2)CC1 +Cc1cc(C)n(-c2ccc(NCC(=O)NCC(F)(F)F)cc2F)n1 +COc1ccc(C(=O)CNC(=O)c2ccccc2)cc1Cl +Cc1csc(NC(=O)CC(NC(N)=O)c2cccs2)n1 +CSc1ccc(CN(C)C(=O)CCC(=O)c2ccc(F)cc2)cc1 +CCc1c(C)nn2c(=O)c(-c3ccccc3)c(C)[nH]c12 +CCC1CCC(N(C)C(=O)c2cccc(N)c2)CC1 +O=C(NCCn1ccc2ccccc21)C1(c2ccccc2)CCOCC1 +Cc1ccc(N2CC(C(=O)NC(C)C#N)CC2=O)cc1 +CC(C)Oc1ccccc1NC(=O)NC(C)(C)c1nccs1 +O=C(NCC1(c2cccc(Cl)c2)CC1)c1ccncc1F +COc1cccc(C(=O)NCCOc2ccc(F)c(F)c2)c1F +CC(C)OC(=O)c1cc(-c2ccc(O)c(N)c2)nn1C +CC(O)CNC(=O)c1ccc(-c2nc3ccccc3s2)s1 +CN(C)C1CN(S(=O)(=O)c2ccc(S(C)(=O)=O)cc2)C1 +Nc1ccccc1SCC(=O)Nc1ccccc1F +Cc1nc(CN2CCN(S(N)(=O)=O)CC2)oc1C +Cc1ccc(C(=O)N(CCc2ccccc2)Cc2ccncc2)cn1 +Cn1ncnc1CNC(=O)NC1(C)Cc2ccccc2C1 +N#CCn1c(C(F)(F)F)nc2cc3c(cc21)OCCO3 +CC(=O)c1cccc(NC(=O)CSc2nncn2-n2cccc2)c1 +NC(=O)c1ccsc1NC(=O)C1(c2ccc(Cl)cc2)CCCC1 +CCOCC(=O)NCc1cn2cc(Cl)ccc2n1 +COc1cc(OC)cc(C(=O)NCC(C)(O)C2CC2)c1 +COC1CCCN(C(=O)CC2Sc3ccccc3NC2=O)C1 +C=CCn1c(C)nnc1SCc1nc2c(F)cccc2n1CC +C#Cc1cccc(NC(=O)N(C)CC(=O)Nc2cccc(C)c2C)c1 +CCOc1cc(C(=O)Nc2c(C)nn(C)c2C)nn1-c1ccccc1 +CCCCOc1ccccc1NC(=O)c1ccncc1 +CC(NC(=O)CN1CCN(c2ccccc2F)C1=O)c1ccccc1 +O=C1C2CCC(C2)N1Cc1ccc(Cl)c(Cl)c1 +CCc1noc(CC)c1CNC(=O)N1CCOCC1C1CC1 +Cc1ccc(NC(=O)NCCOC(=O)Nc2ccccc2)cc1 +Cc1cccc(OCCOC(=O)c2ccc(-n3cncn3)nc2)c1 +CC(=O)c1c(C)nc(C)nc1SCc1cc(C)on1 +CCCCN(CC)C(=O)c1ccc2c(c1)OCC(=O)N2 +COc1ccc(C(C#N)N(C)C(=O)c2ccccc2OC)cc1 +CC(=O)Nc1ccc(Br)cc1NCc1csc(C)n1 +Cc1c(NC(C)CC(C)C)cccc1S(N)(=O)=O +CSc1nc2ccsc2c(=O)n1Cc1ccco1 +COC(=O)c1ccc(CN(CC(C)O)c2ccccc2)cc1F +C=C(C)CN(CC)C(=O)Cc1cc(OC)ccc1OC +CC(=O)NC(C)C(=O)NCCCCN1CCOCC1 +CNC(=O)c1ccc(NCC(=O)Nc2cc(C)ccc2C)cc1 +CC(=O)Nc1nc(CS(=O)(=O)c2cccc(C)c2)cs1 +O=C(CC1CC2CCC1C2)Nc1ccccc1N1CCOCC1 +Cc1cc(CN(C)c2ncccc2C(=O)OC(C)C)no1 +COC(=O)c1c(C)nn(-c2ccccc2)c1-n1c(C)ccc1C +Cc1nn(-c2ccccc2)c(C)c1NC(=O)CC(C)C +COc1ccc(C(=O)c2ccccc2)c(OC(=O)C2CCOCC2)c1 +Cc1ccc2c(Nc3cccc(O)c3)cc(C)nc2n1 +Cc1ccc(Cn2cc(NC(=O)c3cc4occc4n3C)cn2)cc1 +COc1ccc(CC(=O)Nc2ccc(SC)nn2)cc1 +Cc1ccc2ncc(C(=O)Nc3cnn(-c4ccccc4)c3C)n2c1 +CCN(CC)S(=O)(=O)c1ccc(NC(=O)C2CC2)cc1 +Cc1ccc2c(c1F)CCNC2c1ccc(F)cc1N +Cc1ccc(CNC(=O)N2CCOC(C#N)C2)c(OC(C)(C)C)c1 +O=C(C1CC1c1ccco1)N1CCN(Cc2ccco2)CC1 +O=C(Cn1cnc(-c2ccccc2)cc1=O)NCc1ccc(F)cc1 +CC(C)c1cc(C(=O)NCc2ccccn2)n(-c2ccccc2)n1 +COc1ccc(NC(=O)c2cn(C)c3cccc(N)c3c2=O)cc1 +Cc1ccc(C(=O)CSc2nnc(-c3cccnc3)n2N)cc1 +Cc1ccc2oc(=O)c3cnn(CC(=O)N(C)CCC#N)c3c2c1 +Cc1ccc(C)c(NCC(=O)Nc2ccccc2C(N)=O)c1 +CCCNC(=O)C1CCCN(C(=O)NCc2ccnn2C)C1 +COC(=O)c1cccc(CCNC(=O)NC2CCCCCC2CO)c1 +Cn1nc(C2CC2)cc1C(=O)NC1(c2ccccc2)CCCC1 +CC1CCN(CC(=O)NC2CCCCNC2=O)c2ccccc21 +CC(CC(=O)N1CCC(c2cc3cccnc3[nH]2)CC1)n1ccnc1 +CCCCNC(=O)Nc1cc(-c2cccc(Cl)c2)nn1CCO +Cc1cc(SCCO)cc(C)c1Br +CC1CC(C)(C)CC(CO)(NC(=O)NC2CC2)C1 +CCc1nnc2n1CCN(C(=O)C(C)OCC1CCCO1)C2 +C=CCNC(=O)N1CCc2nc(NC(=O)c3ccco3)sc2C1 +CC(C)c1noc(C(C)Nc2ccc(CC(=O)N3CCCC3)cc2)n1 +Cc1ccc(CNCC(O)c2cccc(N)c2)cc1 +O=C(COc1ccc2ccccc2c1)NCc1cccnc1 +N#CCCN(CC(F)(F)F)C(=O)Cn1ncc2ccccc21 +CC(Oc1cccc(N)c1)C(=O)c1ccc2c(c1)OCCO2 +Cc1cc(C)n2cc(COC(=O)c3ccc(O)cc3)nc2n1 +N#Cc1cccc(SCC(=O)Nc2ccncc2)c1 +CN(C)C(=O)c1ccc(C#CCNC(=O)c2cccc(Cl)c2)cc1 +O=c1ccc(C2NCCc3cccc(C(F)(F)F)c32)c[nH]1 +COc1cc2c(cc1OC)C(c1ccc(Cl)cc1)NC(=O)C2 +CCC(C)Nc1nc(OC)nc(Oc2ccc(=O)n(C)n2)n1 +CCc1onc(C)c1NC(=O)c1n[nH]c2c1CCC2 +c1ccc2c(c1)cnn2Cc1nc(-c2cnccn2)no1 +Cc1cccc(-n2cc(C)c(C)c(C#N)c2=O)c1C +CC(C)NC(=O)CNC(=O)NCCc1cccc(F)c1 +COc1cc(CNCCN2CCOCC2)cc(OC)c1 +Cc1nn(C)c(C(=O)Nc2cccc(Cl)c2)c1Br +COc1ccc2c(C)c(CC(=O)N3CCOCC3)c(=O)oc2c1C +COc1ccc2[nH]cc(CCNC(=O)Cc3c(C)nn(C)c3C)c2c1 +Cc1ccc(NC(=O)c2onc(C#N)c2N)c(C)c1 +Cc1ccc2c(c1)nc(CO)n2CC(=O)N1CCOCC1 +O=C(NCCCOC1CCOCC1)N1CCc2ccc(Cl)cc21 +Cc1ccc(C)c(NCC(=O)Nc2cccc(C(=O)NC3CC3)c2)c1 +CC1CN(CC(=O)N(C)CC(=O)NC2CC2)CC(C)O1 +Cn1cccc1C1COCCN1C(=O)c1nccc2ccccc12 +C#Cc1cccc(NCc2ccccc2OC(F)F)c1 +CC(C)Cc1cc(-c2cc(-c3ccc[nH]3)nc(N)c2C#N)n[nH]1 +Cc1ccc(S(=O)(=O)N(CC(=O)N(C)C)CC(F)(F)F)cc1 +O=C(NCc1ccc(-n2ccnc2)cc1)N1CCCC1C1CCCC1 +Cc1cc(C(=O)N2CCCN(C(=O)OC(C)(C)C)CC2)c(C)o1 +Cn1nc(CNC(=O)C2CCCN(C(N)=O)C2)c2c(Cl)cccc21 +CCc1cc(NC(=O)N2CCCC3CCCC32)n(C)n1 +CCCC(=O)Nc1ccc(S(=O)(=O)N2CCCCC2C)cc1 +C=CC1C(C(=O)OCC)=C(C)NC(C)=C1C(=O)OCC +COCCN(CC(N)=O)S(=O)(=O)c1ccc(F)cc1F +CC(=O)NC(C)(C)c1noc(Cc2c(F)cccc2F)n1 +CC(C)(C)c1ccc(-c2nnc(SC3CCOC3=O)n2N)cc1 +CN(C(=O)c1ccc(=O)n(C)n1)C1CCc2ccccc2C1 +Cn1ccc(C(=O)N2CCC(Cc3ccc4ncccc4c3)C2)n1 +CS(=O)(=O)NCC1Cn2nnc(-c3cccc(F)c3)c2CO1 +COC(=O)CC(c1ccc(OC)c(C(C)C)c1)C(C)C +COc1ccc(OC)c(S(=O)(=O)N2CCN(C)CC2)c1 +Cc1cccc(C)c1OCC(=O)Nc1nnc(C2CC2)s1 +Cc1n[nH]c2ncc(C(=O)N3CCCN(c4cccnn4)CC3)cc12 +CCc1ccc(OC(=O)C2CC(=O)Nc3cc(F)ccc32)cc1 +O=C(Cc1cc(Cl)c2c(c1)OCCO2)NC1CCCC1 +CC(C)(C)n1c(C2CC2)nc2ccc(F)c(F)c21 +FC(F)Oc1cccc2c1CCNC2c1ncccn1 +COCc1cccc(C(=O)NCCc2ccccc2C(F)(F)F)n1 +NC(=O)CCN(Cc1ccccc1)C(=O)Cc1ccsc1 +CCC(=O)N1CCCc2cc(NC(=O)C(C)(C)C)ccc21 +COc1ccc(CC(C)NC(C)c2ncc(C)s2)cc1OC +CCN(C(=O)c1ccccc1)c1nnc(-c2ccncc2)s1 +O=C(NCc1ncc[nH]1)C1CCC(=O)N(CCCc2ccccc2)C1 +O=C(CCCc1ccccc1)Nc1ccc2c(c1)CCC(=O)N2 +Cc1nc(CC(=O)N2CCN(c3ncccc3C#N)CC2)cs1 +CC(=O)Nc1ccc(OCC(=O)NC(C)(C)C)cc1 +CCn1ccc(C(=O)NCc2nc3ccccc3[nH]2)n1 +O=C(CSc1ccc2ccccc2n1)NCC(O)c1ccccc1 +NC(=O)CCCNC(=O)C1CC(=O)N(c2ccc(F)cc2F)C1 +CCOC(=O)c1sc2c(c1N)CN(C(=O)OC(C)(C)C)C2 +CN(CC1CCCO1)C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +O=C(c1cnc[nH]c1=O)N1CCOC(C(F)(F)F)C1 +Cc1cc(C2CCCCCN2C(=O)c2ccco2)on1 +CCCCC(CC)C(=O)Nc1ncc(C#CCO)s1 +CCC(C)N(CC(=O)Nc1nccs1)C(=O)c1ccc(C)cc1 +O=C1CCC(COC(=O)c2ccccc2OC(F)F)N1 +O=C(CCc1ccsc1)NC1CCSc2ccc(F)cc21 +CCn1cncc1C(=O)N1CCCC1(C)C(=O)N1CCOCC1 +COc1ccc(NC(=O)CCC(=O)c2cccs2)c(OC)c1 +c1cncc(Oc2ccccc2CSc2ncnc3nc[nH]c23)c1 +CC(=O)Nc1ccc(-c2cc(-c3ccc(O)cc3)nc(N)c2C#N)cc1 +CC(C)Oc1ccc(CNS(=O)(=O)c2ccc(Cl)cc2)cn1 +O=C(Nc1cccc2ncccc12)c1[nH]nc2c1CCC2 +CN(C)C(=O)COc1c(Cl)cc(Cl)cc1Br +CC1CCCC(NC(=O)CCC(=O)N2CCOc3ccccc32)C1C +CCN(CCO)c1ncnc(Nc2cc(C)ccn2)c1N +COc1ccc(-c2nc(C)cc(=O)n2CC(=O)N2CCCC2)cc1 +COc1ccc(CNC(=O)Nc2cc(NC(C)=O)ccc2F)cc1F +O=C(NCC1CCOC1)c1cc(=O)c2ccccc2[nH]1 +CCN(C(=O)Cn1nnc(-c2ccccc2)n1)C1CCCCC1 +O=C(OCC1CC(=O)N(C2CC2)C1)c1cccc(-n2cccn2)c1 +O=C(CNc1ccc(Cl)cc1)Nc1ccccc1C(=O)NC1CC1 +COc1cccc(NC(=O)CNc2cccc(C(=O)NC(C)C)c2)c1 +COc1cccc(-c2cc(C(=O)N3CC(C)CC(C)C3)[nH]n2)c1 +CCCCn1nnnc1CSc1ccncc1N +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)NCCc1cnn(C)c1 +COc1ccc(CNc2ccccc2O)cc1OC +CN(CCOCC1CC1)C(=O)c1cc(C(C)(C)C)n[nH]1 +COc1ccc(OC)c(CC(=O)N2CCOCC2C2CC2)c1 +CC(C)CC(=O)N1CCCN(C(=O)Nc2cccc(Cl)c2)CC1 +CC(C)N(C(=O)CCSc1ccccn1)C1CCC1 +CN1CCN(S(=O)(=O)c2cccs2)c2cnccc21 +Cc1cnc(C(=O)NC2(c3ccccc3)CCOCC2)cn1 +Cn1cnc(CNC(=O)N2CCc3ccc(Br)cc32)n1 +CN1C(=O)CCC(C(=O)NCC2CCCC2)C1c1ccccc1F +CCc1nc2n(n1)CCCC2NC(=O)NCc1cc(C(C)C)no1 +Cc1cc(C(=O)OC(C)C(=O)NCc2ccco2)c2ccccc2n1 +N#Cc1ccc(CN2CCN(C(=O)CC3CCCCC3)CC2)cc1 +Cc1noc(C)c1COc1ccc(C(=O)C(C)C)cc1N +Cn1cnnc1SCc1cc2c(cc1Br)OCCO2 +CCc1cc(C(=O)Nc2nc3c(s2)CCc2c-3cnn2C)on1 +O=C(NCc1cc(Cl)c2c(c1)OCCCO2)Nc1ccccn1 +CC(C)CN(CC(C)C)C(=O)c1ccnc(-n2cncn2)c1 +Cc1ccccc1-n1nccc1NC(=O)CCc1c(C)nn(C)c1C +COc1ccc(-n2c(C)nc3ccc(NC(=O)C4CC4)cc3c2=O)cc1 +CCCn1cc(NC(=O)Nc2cc3[nH]ccc3cc2C)cn1 +Nc1ccc(NC(=O)CCn2ccnc2)cc1C(F)(F)F +CCN(C1CCCCC1)S(=O)(=O)c1c(C)n(C)c(=O)n(C)c1=O +CC(C)n1nccc1NC(=O)N(C)CCOc1ccc(Cl)cc1 +N#CCSc1nnc(NCc2ccc(F)cc2)s1 +Nc1nccnc1C(=O)N1CC2CCCCC21c1ccccc1 +O=C(NCC1CCOC1)N1CCCC1c1ccc2c(c1)OCCO2 +Cc1cccc(C(=O)NC(C)C(=O)NCc2cccs2)c1 +CCOC(=O)COc1cccc(C(=O)NC2CC2)c1 +CCOC(=O)c1cn(CC(=O)Nc2ccc(C)c(Cl)c2)nn1 +N#CCCN(C(=O)CCOc1ccccc1)C1CCCC1 +Cc1ccc(NS(=O)(=O)N2CCOCC2)c(C)c1 +CCCc1cc(C(=O)Nc2ccc(CC(=O)NC(C)C)cc2)[nH]n1 +CS(=O)(=O)N1CCCC(C(=O)Nc2ccc3c(c2)OCO3)C1 +Cc1ccc(-c2nc(CNc3ccc4[nH]nc(C(N)=O)c4c3)co2)cc1 +CCOC(=O)c1c(NC(=O)Cn2cnc(C#N)n2)sc(C)c1CC +CCCn1cc(-c2ccncc2)cc1C(=O)NCC1CC1 +CC(=O)Nc1ccccc1OCc1cc(=O)n2ccccc2n1 +COc1ncccc1CNC(=O)N1CCCC(C)CC1 +CCc1nnc2n1CCN(c1ccc(C#N)cn1)C2 +O=S(=O)(NCc1ccc(O)cc1)c1sccc1Br +CC(NC(=O)Cn1ccnc1)c1ccccc1Cl +COc1cccc2[nH]c(C(=O)Nc3ccc4c(c3)OCCO4)cc12 +CC(=O)c1ccccc1Oc1ccccc1C(N)=O +COCCCNS(=O)(=O)c1cccc2cnccc12 +Cc1cccc(C2CCCN2C(=O)c2ccn(C)n2)c1 +Cc1ccc(C(F)(F)F)cc1NCC(=O)Nc1c(C)nn(C)c1C +CC(C)C(NC(=O)c1cccc(-n2cnnn2)c1)c1ccccc1 +COc1cc(NC(=O)C2CCCC2)ccc1N1CCCCC1=O +CC(C)c1cc(CNC(=O)c2ccccc2S(C)(=O)=O)on1 +CC(C(=O)NC1CCC(C(F)(F)F)CC1)n1ccnc1 +COCCOc1ccc(NC(=O)NC2CCC3CCCCC3C2)cn1 +Cn1nnnc1SCCS(=O)(=O)c1ccc(Cl)cc1 +COC(=O)C(C)NC(=O)c1cc(N)ccc1OC +O=S(=O)(NCc1ccc(F)cc1)c1ccc(Cl)cc1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)NCC1(c2ccccc2)CC1 +COC(C)(C)c1noc(-c2ccnc(SC)c2)n1 +CCOC(=O)c1[nH]c(C)c(C(=O)NC2CC2)c1C +COc1ccc(-c2nnc(SCC#CCO)o2)cc1OC +O=C1c2ccccc2S(=O)(=O)N1C1CCOc2ccccc21 +O=C(NC1CC1)c1cccnc1SC1CCCC1 +Cc1ccc(NC(=O)Cc2ccccc2N)cc1F +O=C(CCc1n[nH]c2ccccc2c1=O)N1CCc2ccccc2C1 +Nc1c(Nc2ccccn2)ncnc1N1CCOCC1 +CS(=O)(=O)NC1CCN(c2cnc3ccccc3n2)CC1 +Cc1nnnn1-c1cccc(NC(=O)CCC2CCCC2)c1 +CS(=O)(=O)N1CCCC(C(=O)NCc2cscn2)C1 +CC(NC(=O)COc1ccccc1O)c1ccccc1 +CCOc1ccc(C(=O)NCc2c(C)cc(C)[nH]c2=O)cc1OC +N#Cc1ccc(C2NCCc3cc(F)c(O)cc32)cc1 +Cc1csc(NC(=O)c2ccc(Cl)c3cccnc23)n1 +Cc1ccc(CN(C)C(=O)CSc2ncn[nH]2)o1 +COc1ccc2cc(CNC(=O)NCc3ccco3)ccc2c1 +COCCN(CC(C)C)C(=O)NCC(=O)N1CCCCC1 +O=C(NCc1ccccc1)c1c[nH]c2c(F)cccc2c1=O +CC(NC(=O)C(C)(C)C)C(=O)Oc1ccccc1Cl +CN(C)C(C(=O)N1CCN(S(N)(=O)=O)CC1)c1ccccc1F +COc1ccc(-c2nc(C)ncc2-c2csc(C)n2)c(O)c1 +COc1cc2ccc(=O)oc2c(CC=C(C)C)c1O +O=C(CNC(=O)c1ccccc1)Nc1ccc2c(c1)C(=O)NC2 +CNC(=O)c1ccc(Nc2ncnc3ccsc23)cc1 +COc1ccccc1OCC1CCCN(C(C)=O)C1 +COc1ccc(-c2noc(CCCC(=O)NC(C)C)n2)cc1 +COc1ccccc1S(=O)(=O)N1CCC(c2ccsc2)CC1 +Cc1nc(CN(C)C(=O)c2ccc(C(N)=O)nc2)cs1 +CCCC(NC(=O)CN1CCOC(C)(C)C1)c1ccccc1 +COCc1cc(C(=O)N2CCCC(n3cncn3)C2)c(C)o1 +Cc1nc2c(c(N3CCOCC3)n1)CN(C(=O)c1cccnc1)CC2 +CC(C)CN(c1ccc2scnc2c1N)C1CC1 +CCOCCNC(=O)Nc1ccc(S(=O)(=O)CC)cc1 +COc1ccccc1C(=O)NCc1cc(Cl)cc2c1OCOC2 +CCNC(=O)CN1CCN(C(=O)c2cc3cccc(OC)c3o2)CC1 +CCOC(=O)C1(NS(=O)(=O)Cc2cccc(C#N)c2)CCCC1 +Cc1ccc2cc(-c3noc(CCC(N)=O)n3)c(=O)[nH]c2c1 +CCC(CC)NS(=O)(=O)c1ccc(F)cc1F +Cc1cc(C#N)ccc1C(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +O=C(Nc1cc(Cl)ccc1SCC(F)(F)F)c1ccncc1 +Cc1nc2ccc(C(=O)NCCc3nnc4n3CCC4)cc2nc1C +Cc1nc2c(cnn2C(C)C)c(C)c1CCC(=O)NCC1CCOC1 +COC(C)(C)c1noc(-c2cnn(-c3ccc(F)cc3)n2)n1 +COc1cc(-c2cccc(F)c2)cc(OC)c1OC +Cc1ccoc1C(=O)NCC(C)CN1CCCC1=O +CCN(Cc1ccccc1NC(=O)Cc1cccc(F)c1F)C(C)=O +CCCn1nc(C)c(CN2CCCC(C(=O)OC)C2)c1C +COCC(NC(=O)c1cc(Br)ccc1O)C(N)=O +CC(=O)c1cc2c(cc1NC(=O)c1[nH]c(C)c(C(C)=O)c1C)OCO2 +Cc1nc(SCC(=O)c2ccc(F)cc2)cc(-c2ccccn2)n1 +Cn1cc(NC(=O)c2ccc(-n3cccc3)cc2)cn1 +CCOCc1nc(Cc2ccc3c(c2)OCO3)n(C)n1 +O=C(NCC(O)c1ccccc1)Nc1cccc2cnccc12 +CCC1Oc2ccc(N)cc2N(Cc2ccc(Cl)cc2)C1=O +CCC(=O)c1ccc(OCc2nnc(-c3cccs3)o2)cc1 +C=CCNC(=O)N1CC(c2nc(-c3ccccn3)no2)C1 +Cc1ccc(NC(=O)C2CC2C)cc1S(=O)(=O)N1CCOCC1 +O=C1CCN(c2ccc(Br)cc2C(F)(F)F)C1=O +Cc1ccc(N(C)C(=O)c2cnc(C3CCCO3)s2)cc1Cl +O=C(OCCc1c[nH]nc1C(F)(F)F)c1ccsc1 +Cc1cnn(CCC(=O)NCCn2c(C)nc3ccccc32)c1 +O=C(NCCc1ccco1)c1cnc(-c2cccnc2)nc1 +Cc1nc(CN2CCN(C(=O)c3ccccc3)CC2)nc2ccccc12 +COc1cccc2c1C(c1ccncc1Cl)NCC2 +Cc1noc(C)c1CN(C)S(=O)(=O)c1ccc2c(c1)CCCC2 +CCn1c(C2CCN(c3cc(OC)nc(OC)n3)CC2)n[nH]c1=O +CC(C)Oc1ccc(C(=O)Nc2sccc2C(N)=O)cc1 +CCC(=O)c1ccc(NC(=O)CS(=O)(=O)c2ccccc2)cc1 +CCOc1ccc(CNC(=O)N2CCCC(O)C2)cc1OC +COc1cccc(CNC(=O)c2cc(F)ccc2Br)c1 +CC(NC(=O)CNc1ccccc1Cl)c1ccc(NC(N)=O)cc1 +O=C1CSc2ccc(NC(=O)c3ccc4c(c3)CCCC4)cc2N1 +CS(=O)(=O)N1CCCc2ccc(NC(=O)c3ccco3)cc21 +CCn1cc(C(=O)NCC2CCN(c3ccccc3)C2)c(C(C)C)n1 +O=C(COc1ccc2ccc(=O)oc2c1)Nc1ccc(Cl)cn1 +O=C(CCc1cnn(-c2ccccc2)c1)Nn1cnc2ccccc21 +O=C(c1ccoc1)N1CCN(Cc2nc(-c3ccsc3)no2)CC1 +C=CCNC(=O)NCCc1nnc2n1CCCCC2 +COC(=O)c1cc(NC(=O)C2CCCC2)ccc1F +CC(c1ccon1)N(C)C(=O)c1csc(-c2cccs2)n1 +O=S(=O)(NCc1ccccc1)NC1CCc2cccnc21 +O=C(CN1C(=O)CCSc2ccccc21)Nc1ccc(F)cc1F +COCC(O)CN(C)C(=O)Nc1ccc(SC)cc1 +Cc1ccc(SCCCNC(=O)c2cc3ncccn3n2)cc1 +Cc1cc(C(=O)CCC(=O)N2CCCC2c2cccs2)c(C)s1 +CCN(CC)C(=O)c1ccc(C(=O)OC2CCCC2OC)cc1 +FC(F)(F)C1CN(c2ccc(-c3ccccc3)nn2)CCO1 +Cn1ncc2c(N3CCCC3)nc(NCCO)nc21 +Fc1cc(Cl)c2c(c1)CCNC2c1cncs1 +CCc1cc(=O)[nH]c2nnc(SCC(=O)NCc3ccccc3)n12 +COc1ccc(C2NC(=O)c3ccccc3N2C)cc1OC +CCn1cnnc1CNC(=O)NCC1CCCC1 +CCCCNC(=O)Cn1c(C)nc2ccccc2c1=O +COC(=O)c1ccc(COc2ccc(C(C)=O)cc2OC)o1 +CCCOc1cccc(NC(=O)C2CC(=O)Nc3ccccc32)c1 +CCC(C)(C)NC(=O)CSc1nnnn1-c1ccc(OC)cc1 +O=C(CCC(=O)c1ccc(F)cc1F)NCc1ccccn1 +Cn1cc(C(=O)Oc2cccc(N3CCCC3=O)c2)c(C(C)(C)C)n1 +CCc1c(C)nc(-c2cccc(Cl)c2)n2c(=O)[nH]nc12 +Cc1cccc(N2C(=O)C(Cc3ccccc3)N=C2N2CCOCC2)c1 +Clc1ccc(Cl)c2c1CCNC2Cn1cnnn1 +Cc1c(-c2ccc3c(c2)OCO3)[nH]c(=O)c(C#N)c1C +N#Cc1ccc(Cl)cc1NCc1ccc(-n2cccn2)cc1 +CCCC(=O)Nc1ccc(C(=O)NC2CCCC2)cc1 +CC(NC(=O)C1Cc2ccccc2O1)C1(N2CCOCC2)CCCC1 +COc1ncccc1CNC(=O)Nc1cccc(C#N)c1 +C=C(c1ccccc1)C1NCCc2ccc(OC)c(OC)c21 +O=C(c1cccc(F)c1)N(CCO)C1CCCCC1 +CC(=O)Nc1nc(CN2CCN(C(=O)c3ccco3)CC2)cs1 +c1nc(N2CCOCC2)c2ncn(Cc3csc(C4CC4)n3)c2n1 +COC(=O)CCNC(=O)Cc1ccc(N2CCCC2=O)cc1 +Cc1cc(=O)cc(C(=O)NCC2COc3ccccc3C2)o1 +Nc1ccccc1CC(=O)NCc1ccc2c(c1)OCO2 +COc1ccc2cc(C(=O)NCC3CCCO3)ccc2c1 +Cc1nnc(NC(=O)c2ccc3[nH]c(=O)[nH]c3c2)s1 +CN(CCC#N)C1c2cc(Cl)cc(Cl)c2CC1O +CC(NC(=O)c1ccc(-c2ccco2)[nH]c1=O)c1nnc2ccccn12 +CC(C)c1cccc(C(C)C)c1NC(=O)NCCO +CC(Sc1nccn1C)C(=O)c1ccc(NS(C)(=O)=O)cc1 +CCOC(=O)C(C)(C)NC(=O)c1ccc(-n2ccnn2)cc1 +O=C(CNC(=O)c1ccc(Cl)cc1O)NCC(F)(F)F +COc1ccc(F)c(NC(=O)CSc2ccc(C#N)cc2)c1 +N#CC1(C(=O)N2CCN(CC(O)c3ccccc3)CC2)CCCCC1 +COc1ccccc1C(C)NS(=O)(=O)c1ccccc1 +COc1ccc2c(c1)CC(C(=O)N(C)CCCc1cnn(C)c1)CO2 +CCn1nnnc1-c1cccc(NC(=O)NCCCO)c1 +CCc1nnsc1C(=O)NCC1CCCCO1 +O=c1c2sccc2ncn1CC(O)COCc1cccs1 +Cc1n[nH]c2ncc(C(=O)N3CCCC3CC(=O)c3ccccc3)cc12 +CCS(=O)(=O)c1ccc(N2CCC(NC(=O)COC)CC2)cc1 +O=c1oc(-c2ccccc2)nn1CC(O)c1ccc(OC(F)F)cc1 +CC(=O)c1c[nH]c(C(=O)OCc2c(F)cccc2Cl)c1 +CN1CC(c2cc(=O)[nH]c(NCc3ccccc3Cl)n2)CC1=O +CCCOC(=O)c1cc(-c2c(O)cc(O)cc2O)nn1C +Cc1cc2cc(C(=O)NCCn3cnnc3C)oc2cc1C +O=C(Nc1cccnc1)C1CCN(C(=O)c2cccc(F)c2)CC1 +Cc1nnsc1C(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 +CCc1nc(CC(=O)OC(C)c2ccc3c(c2)OCCO3)cs1 +O=C(CC1CCCCC1)Nc1cc(-n2cnnn2)ccc1Cl +CC(C)(C)C(=O)NCC(=O)Nc1ccc(OCC2CCOCC2)cc1 +CNC(=O)c1ccc(S(=O)(=O)Nc2ccc3c(c2)OCO3)cc1 +O=C(c1cccnc1Oc1ccccc1)N1CCCC1 +O=C(Cc1cccs1)NCCC(O)c1ccc2c(c1)OCO2 +Cc1noc(C)c1N(C)C(=O)Cc1cccc(OCC#N)c1 +CCCNC(=O)C1CCCN(C(=O)Nc2ccc3c(c2)COC3)C1 +Cc1ccc(N(CCC#N)C(=O)CCc2cccnc2)cc1C +CC(C)c1nc(S(=O)(=O)NCc2cccc(-n3cncn3)c2)c[nH]1 +COc1ccc(S(=O)(=O)NCc2c[nH]nc2C)cc1C +CCOC(=O)C(O)Cc1ncc2c(=O)[nH]ccn12 +Cc1cc(C(=O)NCCC(O)c2ccccc2)no1 +N#Cc1ccc(C(=O)Nc2onc3c2CCC3)cc1 +CCn1c(C2CCCN2C(=O)Nc2cc(C)on2)nc2ccccc21 +Cc1n[nH]c(-c2c(C)nn(-c3ccc(F)cc3)c2C)n1 +Cc1cc(Br)ccc1NCc1ccncc1 +CC1CCCN(C(=O)Nc2ccccc2SCC(N)=O)C1 +COC(=O)C1=C(CN2CCCC2)NC(=O)NC1c1ccc(Cl)cc1 +CC(C)CCOCCC(=O)Nc1cc(N)ccc1F +CC(C)c1ccc(N2CC(C(=O)N(C)Cc3ccoc3)CC2=O)cc1 +O=C(Nc1cccc2cccnc12)C1CC(=O)N(c2ccccc2F)C1 +COC(=O)Cn1ccc(NC(=O)c2n[nH]c3ccccc23)n1 +CCOc1cc(C)ccc1NC(C)c1ccncc1 +C=CCOc1ccc(C(=O)NCC(C)O)cc1OC +CCc1c(C(=O)Nc2ccccc2O)cnn1-c1ccccc1 +CCC(CC)C(=O)NCc1ccc(S(C)(=O)=O)cc1 +CN(Cc1cnn(C)c1)c1cc(-c2ccccc2)nc2ncnn12 +CCN(C(=O)Nc1cccc(N2CCNC2=O)c1)C1CCCCC1 +O=C(NC1CCN(C(=O)Cc2ccccc2F)CC1)c1ccccc1 +COc1cc2c(cc1NC(C)=O)oc1ccccc12 +COc1ccc(SCc2noc(-c3ccco3)n2)cc1 +O=S(=O)(NCCC1=CCCCC1)c1cn[nH]c1 +Cc1ccc(OC(C)C(=O)Nc2cccc(N)c2)cc1 +Cc1cc(F)cc2c1N(C(=O)CCNC(=O)OC(C)(C)C)CCC2 +Cc1cccc(NS(=O)(=O)c2cccc(C(=O)NCCCO)c2)c1 +Cc1ccc(C)c(NC(=O)Cn2nc3c4ccccc4ncn3c2=O)c1 +O=C(Nc1ccc(F)cc1)C1(c2ccccc2)CC1 +CC(C)c1nnc2n1CCN(C(=O)C1CC1c1cccc(Cl)c1)C2 +CC(Cc1c[nH]c2ccccc12)C(=O)NCc1ccco1 +Cc1ccccc1S(=O)(=O)N(C)c1ccc(F)c(N)c1 +COc1cccc(OCC(=O)NC2c3ccccc3CC2O)c1 +COc1cccc(-c2cc(C(=O)N3CCC(C)CC3)[nH]n2)c1 +CCOCC(=O)OCC1CC(=O)N(C)C1c1cccc(Cl)c1 +Nc1cccc(-n2ncc3nc4ccccc4nc32)c1 +Cc1cc(NC(=O)c2cc(-c3ccc(OC(C)C)cc3)on2)no1 +O=C(CCc1ccsc1)NCCc1ccc(-n2cccn2)cc1 +Cn1nc(C(=O)N2CCCC2)c2c1CCC(NCc1cccs1)C2 +CC(C)C(=O)Nc1nc(CC(=O)Nc2cccc(CO)c2)cs1 +CCCCc1ccc(-c2noc(N)c2C(=O)OC)cc1 +N#Cc1cccc(C(=O)NC(c2ccccc2)C2CC2)c1 +CCN(CC)C(=O)c1ccc(-c2ccccc2)cc1 +Fc1ccc2c(c1)C(COCc1ccccc1)NCC2 +COc1cc(CNC(=O)NCCc2c(C)nn(C)c2C)ccc1O +Cc1occc1-c1nnc(SCc2ccc(F)cc2Cl)n1N +O=C(NCC1COC2(CCCC2)O1)c1ccccc1C(F)(F)F +Cc1c(F)ccc2c1C(C(=O)Cc1ccc(O)cc1)NCC2 +Cc1cc(C)n(-c2ccc(Cl)c(C(=O)OCC(F)(F)F)n2)n1 +CC(=O)Nc1ccc(OC(=O)COc2ccccc2F)cc1 +COc1ccccc1N1CCN(Cc2nc(C)c(C(C)=O)s2)CC1 +CC(=O)Nc1cc(C(=O)Nc2cccc(-n3cnnn3)c2)ccc1C +O=C(NCC1OCC(NCc2cccs2)C1O)N1CCOCC1 +CCc1ncc2c(n1)CN(C(=O)C(Oc1ccccc1C)C(C)C)C2 +COCCn1cnnc1-c1cc(N)ccc1Cl +COC(=O)c1sccc1NC(=O)CSc1nccn1C +CC(=O)c1cccc(Oc2ncnc3sccc23)c1 +CCc1nc(CNc2cc(Cl)ccc2OCC2CCCO2)no1 +N#CCCNC1CCS(=O)(=O)c2ccc(F)cc21 +CCc1noc(CN(C)Cc2c(C)nn(C)c2Oc2cccnc2)n1 +C=CCN(c1ccccc1)S(=O)(=O)c1cccc(C#N)c1 +CCN(C(=O)COc1c(OC)cccc1OC)C1CCCCC1 +Cc1cnn(CCc2nc3sc(-c4ccccc4)cc3c(=O)[nH]2)c1 +O=C(NCCc1cccnc1)NCCc1ccccc1F +COc1ccccc1C(C)N(C)C(=O)CC(C)(O)c1ccccc1 +CCC(CC)(CO)NS(=O)(=O)c1cn[nH]c1C +CCOc1cc(N2CCCCC2CO)nc(SC)n1 +Cc1ccc(CN2CCC3C2CC(=O)N3Cc2cccnc2)s1 +Cc1cc(C(=O)N2CCCC2)cc(S(N)(=O)=O)c1C +CCOC1CC(NC(=O)c2cccc(OC)c2F)C12CCCC2 +CC1CCCN1C(=O)CCN(CC1CC1)CC(F)(F)F +O=c1ccc(C2NCCc3c(O)ccc(Cl)c32)c[nH]1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)OCC#N +CN1C(=O)CCOc2ccc(-c3nncc(N)n3)cc21 +CCc1nc(CNC(=O)CN2CCCNC2=O)cs1 +O=C(CCc1ccsc1)NCCNc1ncccn1 +CNc1snc(C)c1C(=O)OC(C)c1nc(C2CC2)no1 +NC(=O)C1CN(C(=O)CCc2ccc(F)cc2)C1 +O=C(NCCc1ccccc1)c1ccc(Nc2ncccn2)cc1 +COc1ccc(Br)c(C(=O)NCc2ccccn2)c1 +Cn1nnnc1SCCC(=O)NCc1cn(-c2ccccc2)nn1 +COc1ccc(C(C#N)NCc2ccccc2)cc1OC +COc1ccc(-c2nc(C)c3ccccn23)c(N)c1 +Cc1ccc(C(=O)NCCCn2cccc2)cc1C +NC(=O)c1cnc(NC(=O)c2ccn(-c3ccc(F)cc3)n2)s1 +CC(C)(COC(=O)c1ncn(-c2ccccc2)n1)c1ccccc1 +CC(C)COC(=O)N1CCC(C(=O)Nc2cccnc2)CC1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccc(F)cc1F +Cc1ccccc1CC(=O)N1CCCC1c1n[nH]cc1-c1ccncc1 +CC(C)C(=O)Nc1ccc(NCC(=O)N2CCc3ccccc32)cc1 +COc1cc(-c2nc3ccc(C)cc3c(=O)o2)ccc1OC(C)=O +CC(O)CNc1ncc(Br)c2c(N)ccc(F)c12 +COC(C)(C)c1noc(CC(NC(C)=O)c2ccccc2)n1 +O=C(CCC1CCCO1)N(CC1CCCCC1)C1CC1 +O=C(c1ccccc1-n1cncn1)N1CC2CC=CCC2C1 +Cc1nc(C)c(CNC(=O)Nc2cc(-c3ccccc3)on2)s1 +COc1ccc2ccccc2c1CNCC(C)N1CCOCC1 +O=C(NCc1ccco1)N1CCCC1c1cccc(F)c1 +Cc1nc(C)n(-c2ccccc2NC(=O)N(C)C2CC2)n1 +CCC(C)C(=O)NC(C)c1ccc(-n2cncn2)cc1 +O=C(COc1ccc(Br)cc1)N1CCC(CO)C1 +CC(=O)Nc1ccc2nc(NC(=O)c3ccc(C)c(Cl)c3)oc2c1 +O=C(Cn1cc(C2CC2)nn1)Nc1c2c(nn1-c1ccccc1)CCC2 +CCCCc1ccc2[nH]c(C)c(CN3CCOCC3)c(=O)c2c1 +CN1CCN(C(=O)c2nnc3sc(-c4ccc(F)cc4)nn23)CC1 +O=C(CCc1nc2ccccc2[nH]c1=O)NCCc1ccccc1 +COc1cc2c(=O)c3ccccc3n(C)c2c2c1OCO2 +CCC(=O)Nc1ccc(NC(=O)c2ccsc2)cc1 +CC(C(=O)NCc1ccc(S(N)(=O)=O)s1)n1ccnc1 +O=C(COc1ccc2c3c(c(=O)oc2c1)CCC3)Nc1ccncc1 +COc1ccccc1CNC(=O)Cn1cnc(C(C)C)cc1=O +CN(Cc1nnc2n1CCC2)C(=O)Cn1ccccc1=O +O=C(c1ccc2c(c1)CCC2)N1CCCC1c1nc2ccc(F)cc2[nH]1 +Cc1cc(C)c(NCC(=O)c2ccc3c(c2)OCCO3)c(C)c1 +CCOc1ccc(CC(=O)Nc2ccc(C(N)=O)cc2)cc1 +CCCn1c(C)nnc1SCc1nnc(-c2ccc(C)cc2)o1 +Cc1nn(CC(=O)N(C)Cc2ccsc2)c(=O)c2ccccc12 +CCN(CC(=O)NC(C)(C)C)C(=O)c1ccc2[nH]cnc2c1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)N(C)Cc2ccoc2C)c1 +O=C(OCCNc1cccnn1)C1CCCN1C(=O)c1ccco1 +COc1ccc(-c2nc(NC(=O)c3ccoc3C)sc2C)cc1 +CN1CC2(CCCN(c3cc(N)nc(N4CCOCC4)n3)C2)OC1=O +COCCCNC(=O)c1cnn2c(-c3ccc(C)c(C)c3)ccnc12 +COc1cc(Cl)c(C)cc1N(C)C(=O)c1ccc(N)cc1 +O=C(NCC(F)(F)F)NC1CCCN(c2ccccc2F)C1=O +CC(C)(C)NC(=O)CSc1nc2ccc(Cl)cc2[nH]1 +CN(Cc1cccc(C#N)c1)c1cncc(-n2cccn2)n1 +COc1ccc2cc(C(=O)Nc3ccccc3F)c(=O)oc2c1 +O=C(c1ccc(=O)oc1)N1CCN(CC(F)(F)F)CC1 +COc1cccc(NCc2ccc(Cl)cc2F)n1 +Cn1cccc1CNC(=O)c1n[nH]c2c1CCCCC2 +CC(C)Cc1nnc(NC(=O)c2scnc2C2CC2)s1 +CCOC(=O)c1cnn2c(C(=O)NC3CCCCC3)ccnc12 +CC(NC(=O)c1ccc2c(c1)OCC(=O)N2)c1cccc2ccccc12 +COc1cc(-c2noc(-c3cc4cccc(OC)c4o3)n2)ccn1 +Cc1cccc(NC(=O)c2cccc(OCC(F)F)n2)c1C +COC(=O)C(Cc1ccccc1)NC(=O)Cc1ccc(C)cc1 +COC(=O)C(NCCN1CCOCC1)c1ccccc1Cl +CN(Cc1ccc(Cl)cc1)C(=O)c1n[nH]c(=O)c2ccccc12 +COCC(=O)N1CCN(Cc2cnn(-c3ccccc3)c2)CC1 +CCc1ccc(C(=O)Nc2ccc(NS(C)(=O)=O)c(Cl)c2)o1 +CCOC(C)C(=O)NC(C)c1ccccc1C(F)(F)F +Cc1ccc(-c2nnc(CCC(=O)NC3CCC(O)CC3)o2)cc1 +CCc1nonc1NC(=O)c1ccccc1Br +COc1ccc(CC(C)CN(C)C(=O)Nc2nccs2)cc1 +Cc1occc1C(=O)NCC(=O)Nc1ccc2[nH]c(C(F)F)nc2c1 +Cc1ccc(CNS(=O)(=O)c2cc3n(c2)CCCN(C)C3=O)cc1 +COC(=O)c1oc(Cn2ncc3ccccc3c2=O)cc1C +COc1ccc(OCc2noc(-c3cc(OC)cc(OC)c3)n2)cc1 +CNc1c(F)cccc1C(=O)N1CC(C)OCC1C +CCNC(=O)CNC(=O)c1ccc(Oc2ccc(F)cc2)cc1 +COc1ccc(-c2noc(CSc3nncs3)n2)cc1 +Cn1ccc(C(NC(=O)CN2CCCS2(=O)=O)C(F)(F)F)c1 +COC(=O)c1ccc(NC(=O)c2cc(F)ccc2N)cc1 +O=C(NCc1ccc(CN2CCCC2=O)cc1)c1cc2ccccc2[nH]1 +COc1ccc(C(O)CNc2c(C)cc(C)cc2C)cc1F +CC1CN(C(=O)CCc2ccccn2)CC1(O)C1CC1 +Cc1cnc(C(C)CNC(=O)NC2CC=CC2)s1 +COc1ccc(C(C#N)C(=O)CC(C)C)c(OC)c1 +CCc1nc(C(C)NC(=O)Cc2ccc(-n3cccn3)cc2)cs1 +CC(C)C(C)(C#N)NC(=O)c1cc(N2CCCC2=O)ccc1Cl +OCc1nc2ccccc2n1Cc1coc(-c2ccccc2)n1 +COc1cc(-c2ccccc2)sc1C(=O)Nc1ccncc1 +Cc1ccn(Cc2csc(-c3ccco3)n2)c(=O)c1C#N +COc1ccc(CC(=O)N2CCC(O)CC2)c(C)c1C +C=CCc1ccccc1OC(=O)C1CCN(C(=O)N(CC)CC)CC1 +Cc1nn(C)cc1CNc1cnn(-c2ccc(C(F)(F)F)cc2)c1 +CN(C)C(=O)N1CCN(C(=O)CCC2CCCO2)CC1 +CCN(Cc1ccccc1)C(=O)Cn1cnc(C(=O)OC)n1 +COc1ccc(OC)c(C(O)c2cccs2)c1 +COCC(C)NC(=O)c1cnc(SC)n1-c1ccccc1 +COC(CNC(=O)COC1CCCCC1)c1ccccc1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccnn2C(C)C)c1C +CCCOC(NC(=O)OC)C(Cl)(Cl)Cl +Cn1cnnc1SCc1ccccc1C(F)(F)F +CC1CN(C(=O)C2CCCCN2S(C)(=O)=O)CC(C)O1 +Cc1cccc(CC(=O)NCc2ccc(-n3cnc(C)c3)cc2)c1 +CCCC(C)NC(=O)C1CCCN(C(=O)Nc2cccc(F)c2)C1 +CC(C)C(=O)NCCNC(=O)C(C)Oc1ccc(Cl)cc1Cl +CC(CCN1CCOCC1)NC(=O)c1cc2ccccc2c(=O)[nH]1 +CNC(=O)c1ccc(NC(=O)CC2CCCC2)cc1Cl +COc1ccc(CCCSc2nncc(=O)n2N)cc1 +NC(=O)Cc1ccccc1NC(=O)c1cc(Cl)c2c(c1)OCO2 +O=C1CCC(C(=O)NCc2ccc(OCC(F)(F)F)cc2)N1 +Cc1ccc2ncc(C(=O)Nc3nnc(C(C)(C)C)s3)n2c1 +O=C(NCc1cccc(O)c1)c1cc(Cl)cn1C1CC1 +O=C1CCCc2c1cnc1nc(-c3cccs3)nn21 +CC1CCCCN1S(=O)(=O)c1cccc(C(=O)NC2CC2)c1 +CCOC(=O)CC(C)(O)C1Cc2ccccc2C(=O)O1 +COc1cccc(OCCNC(=O)c2cccc3ncccc23)c1 +CCC(C)NC(=O)CC1Oc2ccccc2NC1=O +NS(=O)(=O)N1CCCC1Cc1ccccc1Cl +Cc1cc(C(C)NC(=O)Cc2noc3ccccc23)c(C)o1 +CC(O)(CNS(=O)(=O)c1cccs1)c1ccco1 +NC(=O)c1ccc(NCc2nnc(-c3ccccc3)o2)cc1 +Brc1cccc(-c2nnc3n2CCC3)c1 +C#CCOc1ccc(C2NC(=O)C3CCCCN32)cc1OCC +CN(Cc1cnccn1)C(=O)c1ccc(C(=O)Nc2ccccc2)cc1 +Cn1c(=O)c(C(=O)N2CCOCC(O)C2)nc2ccccc21 +CC(C)(C)C(=O)NCCNC(=O)c1ccc2sncc2c1 +Nc1cc(-c2nc(-c3cccnc3)n[nH]2)ccc1Cl +CCc1nnc(SCC(=O)N2CCc3ccccc32)n1CC +COC(=O)Cn1c(C)cc(=O)n2c3ccccc3nc12 +CN(CC(=O)NC1CC1)C(=O)c1cncn1-c1ccccc1 +Cc1[nH]ccc(=O)c1OCC(=O)Nc1cccnc1 +Cc1noc(C)c1CC(=O)N1CCCC(c2n[nH]c(C3CC3)n2)C1 +COCC(=O)NC(C)c1ccc(-n2cncn2)cc1 +Cc1ccc(-n2nc(C(=O)N3CC(=O)Nc4cnccc43)cc2C)cc1 +c1cnn(CCN2CCN(c3cc(N4CCOCC4)ncn3)CC2)c1 +Cc1cn(S(=O)(=O)c2ccc3c(c2)CCCC3)cn1 +Fc1ccc(CN2CCCC(c3nnc(-c4cccnc4)o3)C2)cc1 +O=C(NC1CC1)c1csc(NC2CCCC2)n1 +Cc1cc(C(=O)Nc2ccc3c(c2)NCCC3)n(C)n1 +OCc1cc(-c2ccc(OCCc3ccccc3)cc2)n[nH]1 +CCOc1ccc(-n2nnc(CO)c2-c2ccc(F)cc2)cc1 +CCOc1ccccc1-n1nnc(CO)c1-c1cccc(F)c1 +CN(C)c1nc(-c2ccncc2)nc2c1CCN(C(=O)c1cc[nH]n1)C2 +Cc1n[nH]c(-c2ccc(S(=O)(=O)N3CCOCC3)s2)c1C +CCOCCOc1ccc(Br)cc1N +COC(=O)N1CCC(NC(=O)c2cccc(N(C)C)c2)CC1 +COCCN1C(=O)CC2C1CCN2C(=O)Cc1ccc(F)cc1 +Cc1ccc2c(c1F)CCNC2c1cccnc1F +Cn1[nH]c(=O)c2c(C(=O)N3CCc4cnccc43)cc(C3CC3)nc21 +CC(Oc1ccccc1C#N)C(=O)NC1CCCC1 +CC(C)(C)OC(=O)N1CCC(NS(C)(=O)=O)CC1 +Cc1ccc(NC(=O)N2CCN(C(=O)c3scnc3C)CC2)cc1 +COc1ccc(C(=O)OCc2nc(-c3ccc(Cl)cc3)no2)cn1 +CCOC(=O)c1ccc(N2CCC(O)C2)c(N)c1 +O=S(=O)(NCc1cc2ccccc2o1)c1ccc(F)cc1F +Cc1cc(C(=O)Nc2ccc3oc(C(C)C)nc3c2)[nH]n1 +OCCOc1cccc(-c2nccn2-c2ccc(CCO)cc2)c1 +CCc1noc(CC)c1CNC(=O)C(C)Oc1ccc(C#N)cc1 +Cc1cccc(C)c1NC(=O)CNC(=O)c1ccc2[nH]nnc2c1 +CCCCNC(=O)Nc1ccc(Br)cn1 +Cc1ccc(Cn2nc(C(=O)NC3CC3)ccc2=O)cc1 +O=C(C1CCCOC1)N1CCc2cc(Cl)cc(Cl)c2C1 +CN(C)c1ccccc1NC(=O)NCc1cc(Cl)ccn1 +Cc1cccc(-c2nc(-c3ccc(O)c(N)c3)n[nH]2)c1 +Cc1nc(SCC(=O)N(C)C)c2ccccc2n1 +Nc1ccc(=NS(=O)(=O)c2ccc(F)cc2)[nH]c1 +CNC(=O)C(NC(=O)Nc1ccccc1)c1ccc(F)c(F)c1 +CCn1c(C)cc(C(=O)N2CCN(Cc3cc(C)on3)CC2)c1C +COC(=O)CCS(=O)(=O)Nc1c(C)cccc1N +COC(=O)c1ccc(CSc2ncc(C#N)cc2C#N)cc1 +O=C(NCCS(=O)(=O)N1CCOCC1)Nc1ccc(F)cc1F +O=C(Nc1cc(F)ccc1Cl)c1ccsc1 +CCNC(=O)c1cc2ccc(OC(=O)C(C)C)cc2oc1=O +Cc1ccccc1Cc1nc(CNc2cc(C(N)=O)ccc2C)no1 +Cc1nn(CC(C)C)c(C)c1CC(=O)Nc1ccc2c(c1)OCCO2 +O=C(Nc1ccccc1)c1ccccc1OCCO +Cc1ccc(-c2cc(-c3ccco3)nc(N)n2)cc1 +O=C1c2ccccc2NC2(Cc3ccccc3C2)N1CC(F)(F)F +COc1ccc(CCNC(=O)N(C)Cc2cc(C)on2)cc1 +CCN(Cc1cccs1)S(=O)(=O)c1ccccc1F +CC(C)c1ccc(N(CC(=O)Nc2cccnc2)S(C)(=O)=O)cc1 +CCCC(=O)N1CCN(c2nnc(SCC(N)=O)s2)CC1 +Cc1ccc(CNS(=O)(=O)N(C)C)c(OC(C)(C)C)c1 +CC(C)NC(=O)c1ccc(N)c(OCc2ccc(F)cc2)c1 +Cc1ncc(C(=O)NCC2CCN(c3cnn(C)c(=O)c3)C2)c(=O)[nH]1 +Cn1cc(C2CCCN2C(=O)c2ccsc2)cn1 +Cc1ccc(-c2nc(C)c(C(=O)N3CCN(C(=O)CO)CC3)s2)o1 +CSc1ncc(Cl)c(C(=O)Nc2nc(C)c(C)s2)n1 +O=C(Nc1cc(Cl)cc(Cl)c1)C1CC(=O)n2ncnc2N1 +CCCCCC(=O)CN1CCN(C(=O)c2ccccc2)CC1 +CCCCC(=O)NCCc1ccc(S(N)(=O)=O)cc1 +Nc1c(Nc2ccc(Cl)cn2)ncnc1N1CCCCC1 +COc1cccc(N2CC(C(=O)NC(C)(C)C)CC2=O)c1 +Cc1onc(-c2ccncn2)c1C(=O)N(C)Cc1ccccc1 +Cc1ccncc1NC(=O)NC(CC(C)C)C(=O)OC(C)(C)C +Cc1ccc(-n2nnc3c(sc4nc(C)ccc43)c2=O)cc1 +COCC(C)(NC(=O)c1cc(C(C)C)nn1C)c1ccccc1 +CC(C)OC(=O)c1cc(N)c(N2CCCC2)c(Cl)c1 +COC(=O)CCNC(=O)C(N)c1ccc(F)cc1N +Cc1ncsc1CCC(=O)NCc1nnc2n1CCC2 +COCc1ccccc1CNC(=O)NCCC(=O)N(C)C +CN(C(=O)c1ccccc1N)c1ccccc1Cl +CC(Sc1c(N)cccc1Cl)C(=O)NC1CCCC1 +Cc1csc(C(C)(C)NCC(=O)Nc2cc(C)nn2C(C)(C)C)n1 +CC1c2cccn2CCN1C(=O)CN1CCN(c2ncccn2)CC1 +COc1ccc(OC)c(COC(=O)c2scnc2C)c1 +O=S(=O)(NCc1cscn1)c1ccc(Cl)cc1F +COc1cc(Cl)c(C)cc1NC(=O)c1onc(C#N)c1N +Cc1nc(C)c(C(=O)N2CCCC(NC(=O)c3cnccn3)CC2)o1 +CCC(C)c1ccccc1N1CC(C(=O)NCC(C)C)CC1=O +CCn1cnc2cc(CNC(=O)CCc3c[nH]c4ccccc34)ccc21 +O=c1cc(C2CCC2)ncn1Cc1nc(C2CCCC2)no1 +COCC1CCCN1C(=O)c1cc(S(N)(=O)=O)ccc1F +COC(=O)C1CC(NC(=O)c2cccc3cnccc23)CN1C +CC(C)(C)c1coc(C2COCCN2Cc2ccccn2)n1 +COc1cc(F)c(S(=O)(=O)N(C)Cc2cnn(C)c2)cc1OC +CCCC(C)NC(=O)C(C)Sc1nnc(-c2ccncc2)o1 +CCN1CCN(C(=O)Cn2ccc(C(F)(F)F)n2)CC1 +O=C(CNc1ccccc1N1CCCC1=O)N1CCc2ccccc21 +c1ccc2c(N3CCN(c4ncnc5ccccc45)CC3)ncnc2c1 +CC(C)NC(=O)NCC1(COc2ccccc2)CC(O)C(O)C1 +Cn1nc2n(c1=O)C(=O)N(c1ccc(Cl)cc1)C2 +CNC(=O)c1ccc(CSc2nc(C)c(C)n2CCOC)cc1 +CCc1nnc(NC(=O)NC2CCCC(C(F)(F)F)C2)s1 +COCCN(CC(N)=O)S(=O)(=O)c1ccc(F)c(Cl)c1 +O=C(Cc1c(F)cccc1Cl)Nc1nncs1 +Cc1ccnc2nc(C(=O)NC(C)c3csc(C(C)C)n3)nn12 +Cc1cc(=O)oc(C)c1C(=O)OCC(=O)Nc1cc(C(C)(C)C)no1 +CCCCc1nnc(NC(=O)N2CCN(C(CC)CO)CC2)s1 +COCc1cc(C(=O)Nc2cnccc2OC)ccc1F +N#Cc1ccc(CNCC(c2ccccc2)N2CCOCC2)cc1 +CC(=O)NCCCS(=O)(=O)c1ncccc1Br +CC(=O)N1CCN(Cc2cnoc2-c2ccccc2)CC1 +CCC(=O)N(Cc1ccc(C(F)(F)F)cc1)C1CC1 +COc1ccc(NC(=O)N(C2CC2)C(C)C2CC2)cc1OC(F)F +COc1ccc(C(C)Sc2nncn2C)cc1Cl +Cn1c(SCCCCCO)nc2ccccc21 +O=C(Nc1nc[nH]n1)c1ccc2c(c1)C(=O)c1ccccc1-2 +CCCCS(=O)(=O)NC(C)c1ccc(C)cc1 +Fc1cc(CNc2cnn(CC(F)(F)F)c2)ccc1OC(F)F +COc1cccc(SCC(=O)N2CCCCC2CC(N)=O)c1 +NC(=O)C(NC(=O)c1ccc(O)c(Cl)c1)c1ccccc1 +CC(=O)NC(C)(C)c1noc(CSc2ccccc2F)n1 +Nc1nc(CN2CCN(Cc3ccccn3)CC2)nc2ccccc12 +Cc1ccc(N2CC(NC(=O)N(CCO)CCO)CC2=O)cc1 +NC(=O)C1(N2CCN(C(=O)NCC(F)(F)F)CC2)CCCCC1 +C=CCn1c(SCC(N)=O)nnc1-c1ccccc1OC +O=C(Cn1c(=O)oc2ccccc21)NC1CCCc2ccccc21 +CCN(CC(C)C#N)C(=O)CNc1ccc(C)c(C)c1 +COc1cc(C)ccc1OCCC(=O)Nc1cnn(C(C)(C)C)c1 +O=C(NCc1ccccc1)NC1CCCN(Cc2ccccc2)C1=O +CC1Cc2ccc(-c3cc(COC(=O)c4ccncc4)no3)cc2O1 +O=C(NC1CCCCC1)c1ncn(-c2ccc(Cl)cc2)n1 +CCC(C(=O)c1ccc2c(c1)NCCO2)N1CCN(C(C)=O)CC1 +CCOc1cccc2cc(C(=O)Nc3ccc(OC)cc3)c(=O)oc12 +COc1cccc(C(=O)OCC(=O)Nc2ccc3c(c2)OCCO3)c1 +CCc1nc(CC(=O)N2Cc3ccccc3CC2C(N)=O)cs1 +Clc1cc(CNc2ccc(-n3nccn3)cc2)c2c(c1)COCO2 +O=C(NCc1ccc(-n2cccn2)cc1)C1COc2ccccc2C1 +Cc1ccc(-c2nnc(Cc3ccccc3F)o2)s1 +CC1Cc2ccccc2N1C(=O)c1cccc(NS(C)(=O)=O)c1 +CC(C)C(=O)Nc1ccc(NC(=O)CNc2ccccc2)cc1 +Cn1c2c(c(=O)[nH]c1=O)C(c1ccco1)NC(=O)N2 +CN(C)C(=O)N1CCCC(C(=O)NCCCn2ccnn2)C1 +Cc1ncsc1C1NCCc2cc(F)c(Cl)cc21 +CCC(C)NC(=O)c1nccnc1-c1nc2ccccc2s1 +NC(=O)c1ccc(NCc2ccc(S(=O)(=O)C(F)F)cc2)cc1 +CCCN(C)S(=O)(=O)c1ccc(C(C)=O)cc1 +O=C(c1ccc2nnnn2c1)N1CCCN(CC(F)(F)F)CC1 +CN(C(=O)c1sccc1C#N)c1ccccc1S(C)(=O)=O +Cc1nn(C)c(C)c1CC(=O)Nc1cccc(-c2nnco2)c1 +C#CCN(C(=O)Cc1ccc(F)c(F)c1)c1nccs1 +COC(=O)C1(N)CCOc2c(Br)cc(F)cc21 +Nc1ncccc1C1NCCc2ccc3c(c21)OCCO3 +Cn1c(SCC(=O)NCC(F)(F)F)nnc1-c1ccc(F)cc1 +Cc1nnc(SCC(O)c2cccc(Cl)c2)s1 +Cc1cc(C(C)NC(=O)Cc2ccc(F)c(F)c2)c(C)o1 +CCC(C)n1ncc(C(=O)Nc2cccc(C(N)=O)n2)c1C1CC1 +Cc1cc(C)n(CC(C)CNC(=O)Nc2nccs2)n1 +COC(=O)c1cccc(NC(=O)CSc2nc3ccccc3[nH]2)c1 +CCNC(=O)c1nnsc1-c1ccc(Cl)cc1 +Cc1ccc2c(c1)C1(CCN(C(N)=O)CC1)CN2C(=O)c1ccccc1 +COC(=O)C(CC(N)=O)n1ccnc1-c1ccc(-n2ccnc2)cc1 +CCSc1c(CC(C)C)cnc2c1c(=O)n(C)c(=O)n2C +Cc1nc(SCC(=O)Nc2ccccc2Cl)oc1C +Nc1cnn(CC(=O)NCc2ccc(F)c(Cl)c2)c1 +Nc1cccc(CC(=O)Nc2ccc(F)c(Cl)c2)c1 +Cc1nnc(SCc2ncc(-c3cccc(Cl)c3)o2)n1N +COC(=O)Nc1cccc(NCC(=O)Nc2cc(F)ccc2F)c1 +O=C(NCc1nc(-c2ccncc2)cs1)Nc1ccc(F)cc1F +Cc1ncn(CC(O)COCc2ccccc2)c(=O)c1C +O=C(Nc1cccc(CNC(=O)c2cc[nH]n2)c1)c1cccc(F)c1 +CC(C(=O)Nc1sccc1C(N)=O)N1CCc2ccccc21 +CCc1cccc(NC(=O)Cn2ncc3c([nH]c4ccccc43)c2=O)c1 +Cc1noc(-c2ccc(C(=O)NCc3cccc4ccccc34)cc2)n1 +Cc1ccc2[nH]c(=O)c(CN(Cc3ccco3)C(=O)C(C)C)cc2c1 +Cc1noc(C)c1CN1CCCC(c2cc(C(N)=O)[nH]n2)C1 +CC(C)C(=O)N1CCN(c2ncccc2C(F)(F)F)CC1 +Cc1nc(C)c(C(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)s1 +NS(=O)(=O)c1ccc(CCNC(=O)c2cc(F)cc(F)c2)cc1 +N#CCOc1cccc(CC(=O)Nn2cnc3ccccc3c2=O)c1 +COC(=O)C(C)(C#N)Cc1c(F)cccc1Cl +Cc1noc(C)c1C(=O)N1CC(n2cccn2)Cc2ccccc21 +CN(C)C(=O)C1CCCN(C(=O)c2cccc(-n3cccn3)n2)C1 +Cc1nnc(SCc2nc3cc(Br)ccc3[nH]2)s1 +Cc1ccc(-c2ncc(N3CCOCC3)s2)cc1 +COc1cc(C)c(C(=O)OC2CCCC2n2cccn2)cc1OC +Cc1cnc(NC(=O)c2cccc(CSc3nccn3C)c2)s1 +Cc1nnsc1S(=O)c1ccc(Br)cc1 +Cc1nnsc1C(=O)NC1CCCc2c1cnn2C(C)(C)C +N#Cc1ncn(CC(O)c2ccccc2Br)n1 +COCCCNC(=O)c1cn(-c2ccccc2C(F)(F)F)nn1 +COc1cc(S(=O)(=O)n2c(C)nc3ccccc32)c(OC)cc1C +CC(=O)NCC(=O)Nc1ccc(Br)cc1C(C)C +CC(=O)N1CCCCC1c1cncc(-c2ccccc2C)n1 +CC(C)Oc1ccc(C(=O)N2CCN(CCO)CC2)cc1 +CCOCCCC(=O)OC1CCCc2ccccc21 +CC1(C)CN(C(=O)c2cnccn2)C(c2ccccc2)CN1 +Cc1ccc(C(=O)OCc2cnn(-c3ccccc3)c2)s1 +NC(=O)c1sc2nncc(-c3ccncc3)c2c1N +Fc1ccc(-n2nnnc2CSc2nc3ccccc3[nH]2)cc1 +NC(=O)CSc1nnc(-c2cccc(F)c2)n1N +COc1ccccc1N1CCN(Cc2ccc(C(N)=O)cc2)CC1 +c1cncc(COCC2CN(Cc3cccnc3)Cc3ccnn3C2)c1 +CSc1nsc(NC(=O)N(C)Cc2ccoc2C)n1 +CC(NC(=O)c1ccc(NC(N)=O)cc1)c1ccccc1Cl +COCCN(CC(N)=O)S(=O)(=O)c1ccccc1Cl +COc1cccc(NC(=O)c2ccc(-n3cccn3)cc2)c1 +Cc1cc(C)n(-c2ccc(CSc3nnc(C4CC4)n3C)cc2)n1 +COC(=O)C(C)CC(=O)Nc1ccc(-n2ccnc2)c(F)c1 +CCOC(=O)N1CCN(C(=O)Nc2nc(CC(N)=O)cs2)CC1 +CCOc1ccc(-n2nnc(CO)c2C2CCC2)cc1 +O=C(Nc1cccc(Cn2cccnc2=O)c1)c1ccc2c(c1)CCO2 +COc1cccc(C(N)c2nc(-c3ccccc3F)n[nH]2)c1 +CCNC(=O)c1ccc2c(c1)[nH]c(=O)n2CCOCC +Cc1ccoc1C(=O)NCc1noc(-c2cccs2)n1 +Cc1cc(Cl)ccc1OCC(O)c1ccc(N)cc1 +CCNC(=O)N(Cc1cccs1)Cc1cccn1C +CCOc1cccc(CN(C(C)=O)c2cccc(N)c2)c1 +COCC(=O)Nc1cc(-c2cn3nc(OC)ccc3n2)ccc1C +O=C(Nc1ccn(-c2ncccc2Cl)n1)c1cccc2[nH]ccc12 +COCC1(C(=O)N(C)CCn2cccn2)CCC1 +Cn1cnnc1SCc1ccc(Br)cc1F +O=S(=O)(NCc1ccn(-c2ccccc2)n1)c1cc(F)ccc1F +O=C1CC(c2nc3ccccc3n2CCc2ccccc2)CN1C1CC1 +Cc1cccc(NC(=O)c2c(C)c3ccccc3oc2=O)c1O +COc1nn(C)c2c1CCCN(C(=O)c1ccc[nH]1)C2 +Cc1n[nH]c2ncc(C(=O)N3CCCCCC3)cc12 +CCC(=O)Nc1cccc(OCC(=O)NCc2nnc(C)o2)c1 +COc1cc(C)c(C(=O)N(C)c2nc(C)cs2)cc1OC +Cc1nc(CC(=O)N(C)Cc2cc(C(C)(C)C)n[nH]2)cs1 +Cc1ccc(OC(C)C(=O)Nc2ccnc(C)c2)cc1 +CCOC(=O)C1=C(c2ccccc2)Nc2ncnn2C1c1ccncc1 +FC1(F)CCN(Cc2ccoc2)CC12CCN(c1cnccn1)C2 +Cc1cnn(C2CCCN(C(=O)c3c(C)oc(C)c3C)C2)c1 +COc1ccc(F)cc1NC(=O)NCc1ccc(O)cc1 +CC(C)c1cccc(C(C)C)c1NC(=O)c1ccco1 +COc1ccc(OCC(=O)NCc2ccco2)cc1 +COC(=O)C(C)Cc1ccc(NC(=O)c2cnn3c2CCCC3)cc1 +Cc1cc2nc(C)c(CCC(=O)N3CC(C)CC(C)C3)c(C)n2n1 +CCC(Oc1ccc2c(c1)CCC2)C(=O)NCC1CCCO1 +COc1ccccc1OCCN(C)c1nc(C)cc(C)n1 +CN1CC(NC(=O)c2ccc(O)c(Cl)c2)CCC1=O +Cc1cc(C)n(CC2CCN(C(=O)c3ccn4ccnc4c3)CC2)n1 +O=C(c1cn(-c2ccc(Br)cc2)nn1)N1CCOCC1 +CC(NC(=O)NCc1ccnc(OC(C)(C)C)c1)C1CCC1 +CC(=O)NC(C)C(=O)NCCCc1nc2ccccc2s1 +CCCOc1ccc(CNC(=O)c2sc(C)nc2C)cc1OC +Cn1ncc2c(=O)[nH]c(NCCc3ccccc3)nc21 +Cc1ccc(CCCNC(=O)c2cnc(C)cn2)c(C)c1 +CNC(=O)c1cccc(CN2CCCC(CN3CCOCC3)C2)c1 +O=C(CCn1ccnn1)Nc1ccc(NC2CCCCC2)cc1 +CCNC(=O)CN(C)C(=O)Cc1ccc(Cl)cc1Cl +CCOC(=O)C(Cc1nc2c(ccc3ccccc32)o1)NC +Cc1c(C(=O)Nc2ccn(CCC(C)C)n2)cnn1-c1ccncc1 +O=C(CC1CSc2nc3c(c(=O)n21)CCC3)NCc1ccncc1 +NC(=O)c1ccc(NC(=O)c2cccnc2N2CCCCC2)cc1 +CC(O)CN1CCN(CCOc2c(Cl)cccc2Cl)CC1 +COCc1cccc(NC(=O)c2cc3c([nH]c2=O)CCCC3=O)c1 +CN(Cc1ccccc1Cl)C(=O)NCC(=O)N1CCCC1 +COc1cccc2cc(C(=O)Nc3cccc(-n4cnnc4)c3)oc12 +CC(O)(CNC(=O)c1cc(-c2ccccc2)on1)c1ccco1 +COc1cccc(C(CNS(=O)(=O)c2cccc(C)c2)OC)c1 +Cc1c(C(=O)N2CCCCC2C)oc2c1C(O)CC(C)(C)C2 +CC1CCN(C(=O)C(C)S(=O)(=O)c2nc3ccccc3[nH]2)CC1 +CC(=O)NC(C)C1NCCc2ccc(F)c(F)c21 +Cn1cc(S(=O)(=O)N(CCc2cccc(F)c2)C2CC2)cn1 +O=C(Nc1ccnn1Cc1cnn(-c2ccccc2)c1)c1cccnc1 +Cc1nc(NC(=O)C(C)Sc2ncnc3c2cnn3C)sc1C +Cn1cnc(CNS(=O)(=O)c2cc(C(F)(F)F)ccc2F)n1 +CN1C(=O)Cc2cc(C(=O)N3CCCCC3)ccc21 +Cc1ccc(NC(=O)c2ccc(OCC(F)F)nc2)c(F)c1 +CCOC1CC(N(C)C(=O)c2nccn3ccnc23)C1(CC)CC +COc1c(C)cnc(CNC(=O)NCCCc2ccccc2)c1C +CC(Cc1ccccc1)NC(=O)C1CCCNC1=O +CN(C)c1ccccc1C#CCNC(=O)c1nc2ccccc2s1 +Cc1noc(C)c1C(C)NCc1cnn(-c2ccccc2)n1 +Cc1occc1C(=O)Nc1ccc(C(F)(F)F)cc1N +CC(C)(C#N)C(=O)Nc1cc(S(C)(=O)=O)ccc1F +COc1ccccc1CN(C)C(=O)c1ccc(SC)cc1 +O=C(c1csc2ccccc12)N(CCO)C1CC1 +NC(=O)N1CCC(C(=O)NCc2ccnc(OC3CCCC3)c2)CC1 +O=C(CS(=O)(=O)c1ccccc1Cl)Nc1cc(F)ccc1F +COCCc1cc(N)n(-c2cccc(Cl)c2C)n1 +CC(C)(C)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +CC1CCN(S(=O)(=O)c2cnn(C)c2)c2ccccc21 +CCOC(=O)c1c(NC(=O)Cc2csc(C)n2)sc(C)c1C +COC(=O)c1c(C(=O)OC)c2c3ccccc3ccn2c1C(C)=O +CCOC(=O)c1c(S(=O)(=O)N2CCCC2)n[nH]c1C +NS(=O)(=O)c1ccc(OCCSc2ncccc2Cl)cc1 +CCC(NCCc1nccs1)c1ccccc1OC +O=C(NCCc1c(F)cccc1F)c1cc(F)cc2[nH]cnc12 +CCSc1cc(C(=O)Nc2cc(C(N)=O)cc(F)c2C)ccn1 +CN(C)c1cccc(OCC(CC#N)N2CCCCC2)c1 +CCn1cc(NC(=O)c2cnc3ccccc3n2)ccc1=O +CC(C)c1ccc(C(O)CCC(=O)NCc2ccco2)cc1 +NC(=O)CC1CCN(c2ncnc3[nH]ncc23)CC1 +CC(OCC(F)(F)F)C(=O)Oc1cccc(N2CCCC2=O)c1 +COc1ccc(NC(=O)NCC2(O)CCCCC2)cc1C(=O)N(C)C +c1ccc(Cn2cc(-c3noc(-c4cccnc4)n3)nn2)cc1 +c1ccn2cc(CSc3nnc(-c4ccncc4)n3C3CC3)nc2c1 +COC(=O)CC1CN(CCN(C)c2ccccc2)CCO1 +CC(C)Oc1ccc(C#N)cc1NCc1nnnn1-c1ccccc1 +CCc1c(C(=O)N(C)CCCNC(C)=O)cnn1-c1ccc(F)cc1 +O=C(NCC1Cc2ccccc2O1)Nc1cnn(-c2ccncc2)c1 +CC(CNC(=O)NCC1(C)COC1)c1nc(-c2ccccc2)no1 +CCCC(C)C(=O)Nc1ccc(OC)nc1N1CCN(C(C)=O)CC1 +NC(=O)c1ccc(NC(=O)c2cccc(-n3cccn3)n2)c(F)c1 +CC(=O)Nc1nc(COC(=O)c2cnc3ccccc3n2)cs1 +CNc1cc(C(=O)N2CCC2c2cccc(OC)c2)ccn1 +COc1cc(C)cc(C(=O)NC2CC(C)OC(C)C2)c1O +CC(C)Cn1cc2c3c(cccc31)CN(C(=O)C1CC1)CC2 +CCCn1cnnc1C(C)NC(=O)Nc1ccc(C#N)cc1CC +Cc1ccc(CNC(=O)Nc2nnc(-c3ccsc3)s2)s1 +CC(=O)N1CCc2cc(Nc3cccc(O)c3)ccc21 +CN(CC1CCCC1)C(=O)NCCNC(=O)C1CC1 +CC1CCC(NC(=O)Nc2ccc3c(c2)OCCO3)CC1 +Cc1cc(C(=O)N2CCOC(C(F)(F)F)C2)c2ccc(F)cc2n1 +Nc1nccnc1C(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 +Cc1cc(C)c(C)c(OCCC(=O)NCC(N)=O)c1 +CC(=O)c1ccccc1NC(=O)c1cccc2cccnc12 +Cc1nc2ccc(N)cc2n(Cc2ccccc2)c1=O +CSc1nc(N)nc(SCc2ccccc2Cl)c1C#N +Cn1nnnc1NCc1cc(Cl)ccc1OCc1ccccc1F +CC(C)N1CC(NC(=O)c2cc(CN3CCOCC3)on2)CC1=O +CCCN(CCC)C(=O)c1ccc(Br)cc1 +Cn1ccnc1SCC(=O)c1cccc(N2CCCC2=O)c1 +COc1cccc(CC2CN(Cc3nc4ccccc4[nH]3)CCO2)c1 +CCC(C)NC(=O)Nc1cc(C(=O)NC)ccc1Cl +CC(C)OC(=O)CSc1ccc2c(c1)CCC2 +CCOc1ccc(SCC(=O)N(C)CC(C)O)cc1 +CC(=O)Nc1cccc(OCCNC(=O)NCc2cc(C)on2)c1 +COc1ccc2[nH]cc(C3=CCN(C(=O)c4cc(C)n[nH]4)CC3)c2c1 +Cc1nc(CN2CCN(C(=O)c3sccc3C)CC2)no1 +CCS(=O)(=O)N1CCOC2(CCCN(c3nnc(C)o3)C2)C1 +COc1ccc(C(O)CCCC(=O)N2CCN(C)CC2)cc1 +Cn1cc(S(=O)(=O)NCCCOC2CCCC2)cn1 +Cc1nc2cc(-c3n[nH]c(C)c3Br)ccc2o1 +N#Cc1ccc(C(N)c2nnc(-c3ccccc3)o2)cc1 +Cc1nnn(CC(=O)Nc2ccnn2C2CCCCC2)n1 +Cc1ccnc2nc(C(=O)N3CCCc4c(F)cc(F)cc43)nn12 +COC(=O)c1nsc(C(=O)Nc2cccc(F)c2)c1N +O=C(Nc1c[nH]ccc1=O)c1cc2ccccc2n1Cc1ccccc1 +Cc1nc(-c2csc(S(=O)(=O)N(C)Cc3ccco3)c2)no1 +N#Cc1ccc(CSc2ccccc2C(=O)NCC(N)=O)cc1 +CCC(=O)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 +Cc1ccc(NC(=O)CCc2ccc3c(c2)OCO3)nc1 +Cc1nn(-c2ccccc2)c(C)c1N1CCN(C(=O)CC(C)C)CC1 +O=C(CN(C(=O)c1csnn1)c1cccc(F)c1)NC1CCCC1 +COc1cc(F)c(C(C)NC(=O)c2cc(F)ccc2F)cc1OC +Cc1ccc(-c2cc(C(=O)N(C)CC(C)(CO)CO)[nH]n2)cc1 +Cc1cc(C)nc(SCC(=O)Nc2nnc(CC(C)C)s2)n1 +Cc1c(C#N)c(NC(=O)CN(C)CCC#N)n(Cc2ccco2)c1C +CSc1ccccc1NCc1ccncc1Cl +CCc1ccc(C2COCCN2S(=O)(=O)CC2CCOC2)o1 +COc1cc(OC)c2c(c1)C(c1ccoc1)NCC2 +O=C(NC1CCN(c2nc(-c3ccc(F)cc3)cs2)CC1)C1CC1 +N#CCCN(Cc1ccccn1)Cc1cc(Cl)ccc1F +O=C(Nc1ccc(SCc2cccnc2)cc1)c1cccnc1 +Cc1c(-c2ccncc2)n[nH]c1NC(=O)c1cc(F)cc(Cl)c1O +COc1cc(C)ccc1OC(=O)c1ccc(C)nc1 +COc1ccc(C(=O)NCC(C)(O)c2ccsc2)c(O)c1 +O=C(Cc1ccccc1)Nc1nnc(-c2ccco2)s1 +NC(=O)C1(CNC(=O)C2CC(=O)N(c3ccccc3)C2)CCOCC1 +COCC(=O)NCC1CC(=O)N(c2ccc(C)cc2)C1 +Cc1noc(C)c1C(C)NC(=O)NC(C)CC(O)c1ccccc1 +NC(=O)C1CCCN(C(=O)CN(Cc2ccco2)c2ccccc2)C1 +CCOc1ccccc1NC(=O)CSc1ncccc1C#N +CCOCC(=O)N1CCC(C(=O)N2CCCCCC2)CC1 +COCCN(CC(=O)N(C)C)C(=O)c1cccc(Cl)c1 +CCCc1nc(CC)sc1-c1nnc(NC)s1 +CCc1nnc(CNC(=O)c2cc(-c3cccn3C)n[nH]2)s1 +Cc1cc(NC(=O)c2ccc3c(c2)[nH]c(=O)n3C2CCCC2)[nH]n1 +O=C(Cc1cccc(F)c1F)Nc1cccc(-n2cnnc2)c1 +CNC(=O)NCC(=O)NC(c1ccccc1)C1CCC1 +COCCn1nc(C(=O)Nc2ccccc2COC)ccc1=O +Cn1cc(C(=O)NCC(C)(C)O)c(C(C)(C)C)n1 +CN(CC1CCCC1)C(=O)Nc1ccc(C#N)cc1 +Cc1nnc2sc(-c3ccccc3NC(=O)c3ccccc3)nn12 +CNC(=O)CN1C(=O)COc2c(OC)cc(CO)cc21 +N#Cc1ccc(C2NCCc3cc(O)ccc32)c(F)c1 +CC(OC(=O)c1cccn1C)C(=O)Nc1cccc(C(F)(F)F)c1 +O=C(c1cnc(C2CC2)nc1)N1CCN(Cc2cccnc2)CC1 +CC(CNS(=O)(=O)c1ccccc1)c1nc(-c2ccccc2)no1 +COC(=O)c1cc(CNC(=O)c2cc(C)no2)ccc1OC +CC(C)c1nnc(NC(=O)N2CCCCC2CCO)s1 +O=C(Nc1ccnn1Cc1ccc(Cl)cc1)C1CC2CCC1O2 +O=C(Cn1cc(NC(=O)Nc2ccc(F)cc2)cn1)NC1CC1 +O=C(Cn1cc2c(n1)CCCCC2)Nc1ccc(F)cc1F +Cc1ccc(CCC(=O)NC(C)c2ccncc2)cc1 +COCCn1c2c(ccc1=O)CCN(C(=O)C1CCOC1)CC2 +N#CCCN(CCC#N)C(=O)CSc1ccncc1 +O=C(OCCOc1ccccc1)c1cnc(C2CCCO2)s1 +COc1ccc(-c2cc(C(=O)NCc3cccnc3)sc2C)cc1 +O=C(CC1C=CCC1)Nc1ccc(-n2cncn2)nc1 +Cc1oc(-c2cccs2)nc1CS(=O)(=O)c1ccccc1 +CCc1noc(COc2ccc3c(c2)CCCC3=O)n1 +Cc1csc(NC(=O)c2ccc(N)cc2Cl)n1 +CCCNC(=O)c1cccc(NC(=O)NC(C)c2ccncc2)c1 +COc1ccc(C(C)(C)C)cc1S(=O)(=O)n1ccnc1 +N#Cc1cc(F)cc(C(=O)N2CCOCC(CO)C2)c1 +O=C(NCCn1nc(C2CC2)n(-c2ccccc2)c1=O)c1cccnc1 +O=C(CNC(=O)c1ccco1)c1ccc2c(c1)CCC2 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)N1CCC(O)CC1 +Cc1csc(NC(=O)Cn2ccc3ccc(Cl)cc32)n1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)OCC(C)C)c1 +CC(=O)Nc1ccc(C(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1 +Cc1nc2ccccc2n1CCNC(=O)NCCc1ccccn1 +O=C(Nc1ccccn1)c1cnc(Cc2ccc(F)cc2)s1 +O=C(NCc1noc(Cc2ccccc2)n1)c1cccc2ccnn12 +O=C(CCn1cncn1)Nc1ccc(NC(=O)NC2CC2)cc1 +COCCNC(=O)C(N)c1ccc(F)c(F)c1F +Cc1ccc(-c2noc(C(=O)NCc3cccnc3)c2N)cc1 +COC(=O)c1ccc(F)cc1NCc1cccnc1 +COC(=O)C(C)(C)NC(=O)CC1CCCc2cc(OC)ccc21 +Cc1cc(CN(C)C(=O)Cc2coc3cc(C)c(C)cc23)no1 +CC(C)(C)n1nc2c(c1-n1cccc1)CN(C(=O)Cc1ccccc1)C2 +O=C(OCC1CC(=O)N(C2CC2)C1)C1CCCN1C(=O)C1CCCC1 +CCOc1c(Cl)cc(CN2C(C)COCC2C)cc1OC +CCC(CCO)CNc1nn2c(=O)ccnc2s1 +O=C(C(O)c1ccc2c(c1)OCCO2)N1CCOCC1 +Cc1cc(SCC(=O)Nc2ccccc2)nc(=O)[nH]1 +CCc1nc(COC(=O)C2CC(=O)N(c3ccc(C)cc3)C2)cs1 +CC1CCc2sc(C(=O)NCCc3noc(C4CC4)n3)cc2C1 +CCOC1CCC2C1OCCN2C(=O)c1ccnnc1 +CCOC(=O)Cc1nnc(Oc2ccccc2)s1 +COCCc1n[nH]c(N)c1-c1ccccc1Br +CC(C)CN(Cc1ccsc1)C(=O)c1ccc(-n2cnnc2)cc1 +CCc1nc2c3cnn(-c4ccc(C)c(Cl)c4)c3ncn2n1 +O=C(NCc1ccc(F)cc1)c1cc(-c2cccnc2)[nH]n1 +Cc1cc(C)c(C#N)c(SCC(=O)Nc2cc(C(C)C)no2)n1 +Cc1cccc(NC(=O)NCc2cccc(NC(=O)c3ccco3)c2)c1 +COc1ccc(S(=O)(=O)N(C)c2ccccn2)c(C)c1 +Cc1ccc(C(C)NS(=O)(=O)c2cccc(C(N)=O)c2)o1 +CNS(=O)(=O)c1cccc(CNc2nc3ccccc3nc2C)c1 +O=C(NCCNC(=O)C1CCCCC1)c1cc2scnc2[nH]1 +CC1CC1CNC(=O)Cc1csc(-c2ccco2)n1 +CC(NC(=O)NCC1CC1C)c1ccc(F)cc1 +CCN(CC)C(=O)CNC(=O)c1cc2ccccc2cc1O +CN(C(=O)c1ccc(C#N)cc1)C(c1cccc(F)c1)c1ccccn1 +CC(=O)Nc1ccc(NC(=O)CCn2ccc(C)n2)cc1 +CCSc1ccc(CC(=O)Nc2nc(C)c(C)s2)cc1 +C=CCNC(=O)c1c(C)nn(Cc2ccccc2)c1C +Cn1ccc(N2CCCC(NC(=O)c3scnc3C3CC3)C2=O)n1 +COC(=O)CCN(C)C(=O)C(NC(C)=O)C(C)C +OCCCSc1nnc(-c2ccc(OC(F)F)cc2)o1 +Cc1nn(C)cc1C(=O)OCCCOc1ccccc1Cl +CC(=O)N1CCN(C(=O)c2cn(Cc3ccccc3F)nn2)CC1 +O=C(NCc1cccnc1-n1ccnc1)c1cc2ccccc2c(=O)[nH]1 +Cc1cccc(C(N)C(=O)NCCCCCO)c1F +CN(CCc1ccc(F)cc1)C(=O)COCC1CC1 +O=C(C1CNc2ccccc2O1)N1CCCCC1CCO +CCn1ncc(CNS(=O)(=O)c2cnn(CC)c2C)c1C +CCOc1cc(CO)cc2c1OCC(=O)N2CC(C)C +Cc1cc(C)cc(C(=O)NCC(=O)OC(C)C#N)c1 +Cc1oc(-c2ccccc2)nc1COc1nnc2ccccn12 +CCOC(=O)c1nn(-c2ccccc2)c(=O)cc1N1CCCCCC1 +CCn1c(SC2CCOC2=O)nnc1-c1ccccc1 +COC(=O)c1ccsc1NC(=O)CSc1ccc(C)cc1 +CC(=O)Nc1cccc(NCC(=O)NC(C)c2ccc(F)cc2)c1 +O=c1[nH]n(-c2ccc(F)cc2)c(=O)c2ccccc12 +CCc1nnc(NC(=O)Cc2c(Cl)cccc2Cl)s1 +Cc1ocnc1CNC(=O)Nc1cccc(OC(F)F)c1 +CC(C)c1n[nH]c(C(=O)NC2CCCC2)c1Br +Fc1ccc(F)c2c1CCN(Cc1nnc(-c3cccs3)o1)C2 +CCN(C(=O)COc1ccc(F)c(F)c1)C1CC1 +CC1CC1C(=O)Nc1cc(C(F)(F)F)ccc1-n1cccn1 +CCOC(=O)NCC1CCN(C(=O)Oc2ccccc2)CC1 +Cc1cccn2c(CC(=O)N3Cc4ccccc4C(O)C3)cnc12 +Cc1cc(=O)oc2cc(OC(=O)C3COc4ccccc4O3)ccc12 +COc1ccc(C(=O)Nc2sccc2C(N)=O)cc1 +Cc1csc(CN2CCC3(CC(NC(=O)N(C)C)CCO3)C2)n1 +CN(C)C(=O)c1cc(NC(=O)NCC(C)(O)c2ccccc2)ccn1 +COC(=O)CNC(=O)c1cc(-c2ccccc2)on1 +CCc1nnc(NC(=O)Cn2nncc2CO)s1 +CCCc1nc(CN2CCN(C(=O)c3ccccc3F)CC2)cs1 +Cc1cc(C(=O)Nc2nc(-c3cc4ccccc4o3)cs2)on1 +COCC1CCCN(C(=O)c2cc(OC)c(C)c(OC)c2)C1 +COC(=O)C1CCCCN1C(=O)c1cc(Br)ccc1F +CCC(C)NC(=O)c1ccc(S(C)(=O)=O)cc1 +CCOC(=O)c1ccc(NC(C)C(=O)N(C)C)nc1 +Cc1n[nH]c(C)c1S(=O)(=O)NC(CO)Cc1ccccc1 +Cc1cc(CN(C)C(=O)c2ccc(N3CCCC3=O)cc2)no1 +O=C(CSc1ccc(-c2ccco2)nn1)NC1CCCCC1 +O=C1Cc2cc(Cl)cc(C(O)c3cccc(Cl)c3)c2N1 +Cc1ccc(N(C)CC(O)c2ccc(C#N)cc2)c(C)c1 +CN(CCc1cn[nH]c1)c1nc2nonc2nc1N1CCCCC1 +O=C(NCc1ccco1)c1ccc(-n2cccc2)cc1 +NC(=O)c1ccccc1NC(=O)CCSc1ccc(Cl)cc1 +COc1ccc(S(=O)(=O)n2[nH]c(=O)c(CCO)c2C)cc1 +Cc1ccnc(NC(=O)c2cc3sccc3n2C(C)C)c1 +CCCS(=O)(=O)N(CC)Cc1ccccc1Cl +O=C(c1ccccc1OCc1ccc(F)cc1)N1CCC(O)CC1 +Cc1ccc(C(N)=O)cc1NC(=O)c1cnccn1 +COCCOCC(=O)Nc1c(F)cccc1N1CCCC1 +CC(=O)Nc1ccccc1OS(=O)(=O)c1ccc(C#N)cc1 +COc1cccc(CCC(=O)N2CCC(CC(N)=O)CC2)c1 +COc1ccc(C)cc1-n1ccnc1SCC(=O)NC(C)(C)C +Cc1nn(C)c(C)c1C(C)NC(=O)c1n[nH]c(=O)[nH]1 +CCc1nc(Cn2cnc3nc(SC)sc3c2=O)cs1 +CCc1nnc(CN2CCOC(c3ccc(Cl)c(Cl)c3)C2)o1 +Cc1ccncc1NC(=O)c1cccc(S(C)(=O)=O)c1 +Cc1nc(N(C)C(C)c2cccnc2)c2nc(C)oc2n1 +CCC(=O)Nc1nnc(-c2ccc(S(=O)(=O)CC)cc2)o1 +Cn1cncc1C1NCCc2ccc(O)c(Cl)c21 +Cc1ccc(SCCCC(=O)Nc2sccc2C(N)=O)cc1 +CC(N)c1ncc(-c2cccc(S(C)(=O)=O)c2)nn1 +COC(=O)CCCS(=O)(=O)N(C)C1CCOCC1 +CC(C)n1cc(C(=O)c2ccccc2O)cc(C#N)c1=O +Cn1cc(C(N)=O)cc1C(=O)OCCc1c[nH]nc1C(F)(F)F +CCOC(=O)CN(C)C(=O)c1ccc(F)c(F)c1 +O=C(Cn1c(CO)nc2ccccc21)Nc1cccc(Cl)c1 +CCCCC(CC)CNC(=O)N1CCC(C(N)=O)CC1 +CCOc1ccc(NC(=O)c2csc(-n3cccc3)n2)cc1 +O=C(NCCN1CCOCC1)c1cccc(CN2CCCC2=O)c1 +CN(C(=O)CCc1ccccc1)c1ccc(S(C)(=O)=O)cc1 +Cc1ccc(NC(=O)C(C)Sc2cccc(N)c2)cc1 +Cc1ccc(-c2noc(COc3ccc(S(C)(=O)=O)cc3)n2)cc1 +COc1ccc(C)cc1NC(=O)Cc1csc(C)n1 +CCCC1CN(C(=O)Nc2ccc(-n3cc(C)cn3)c(F)c2)CCO1 +Cc1cc(F)ccc1NC(=O)C1COc2ccccc2O1 +CCOc1cc(C(=O)N2CCCC2)cc(Cl)c1OC +COc1ccc(C(=O)Nc2nn(C)cc2C#N)cc1-c1ccccn1 +CCCNC(=O)CNC(=O)c1cc(N)cnc1C +CC(C)c1cc(-c2nc(C3CCOC3)n[nH]2)nc(N)n1 +O=c1c2cnccc2ncn1Cc1n[nH]c2c1CCCCC2 +CCn1cc(C(=O)N(C)c2ccccc2)c(=O)c2c(N)cccc21 +Cc1c(Cl)cccc1NC(=O)C(C)OC(=O)c1cccnc1 +Cc1ccc(C)c(C(C)NC(=O)Nc2ccncc2)c1 +CCN(CC)C(=O)CCC(=O)N(C)Cc1cccc(Cl)c1 +C1CCc2nc(-c3nc4n(n3)CCCCC4)nn2CC1 +C#Cc1cccc(NC(=O)CNC(=O)CCC(C)C)c1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccc(-n2cccn2)cc1 +CC1(C)CNC(=O)c2nc(C3CCOCC3)[nH]c2C1 +CC(NC(=O)c1cc(C(N)=O)cs1)c1ccc2c(c1)CCCC2 +Cc1noc(C)c1-c1ccc(C(=O)Nc2ccncc2)s1 +CC(C)Oc1ccccc1NS(=O)(=O)c1ccccc1N +COC(=O)C1(NC(=O)c2ccc3c(c2)CCN3C(C)=O)CCCCC1 +Cc1ccc(NC(=O)Cn2ncc(Cl)c(Cl)c2=O)c(C)c1 +COc1ccc(C(=O)N(C)c2cc(C)cc(C)c2)cc1-n1cnnn1 +CC(C)(C)NC(=O)c1ccc(-c2cc(N3CCCC3)ncn2)cc1 +Cc1csc(C(C)N(C)C(=O)CCN2CCOCC2)n1 +COc1ccc(C(=O)N2CC=C(c3ccc(O)cc3)CC2)c(O)c1 +Cc1ccc2c(n1)OCCN2C(=O)c1ccc(F)c(Cl)c1 +CN1CC(C(=O)NC2CC2c2cccc(Cl)c2)CC1=O +c1ccc(-n2c(SCc3cscn3)nnc2C2CC2)cc1 +Cc1ccc(S(=O)(=O)C(C)C(=O)Nc2ccccc2F)cc1 +Cc1nnc2n1CC(CNc1c(C#N)c(=O)n(C)c(=O)n1C)CC2 +COc1cc(Nc2ccc(C#N)cn2)cc(OC)c1OC +N#CCCn1c(SCc2ccc(C#N)cc2)nc2ccccc21 +Cc1cc(C)c(CNC(=O)c2cncc(Br)c2)c(C)c1 +Cc1cc(COC(=O)CCn2ccc(=O)[nH]c2=O)no1 +CC(C)CC(=O)Nc1cccc(OCc2cccnc2)c1 +CC(=O)Nc1ccc(OC(=O)c2cnc(C3CCCO3)s2)cc1 +Cc1cc(C(=O)NC(C#N)C(C)(C)C)ccc1-n1cncn1 +CC(c1cccs1)N(C)C(=O)c1cnc(C2CCCO2)s1 +CCc1cc(C(N)=O)c(NC(=O)Nc2ccc(OC)cc2)s1 +O=C(Nc1ccccn1)N1CCN(Cc2cccnc2)CC1 +CCN(CC(=O)N1CCNC(=O)C1)Cc1ccc(C#N)cc1F +Nc1ncc2c(n1)CN(CCc1ccccc1F)C2=O +CC(C)c1cc(C(=O)N2CCN(c3ncccc3Cl)CC2)n[nH]1 +Cc1ccccc1C(=O)N(C)C(C#N)c1ccccc1F +Cc1ccc(NC(=O)N(C)C)c(C(=O)N2CCCC2)c1 +O=c1cc(-c2ccccn2)nc(-c2cnccn2)[nH]1 +CC(Cn1nc(-c2ccco2)ccc1=O)C(=O)NC1CC1 +CCCNC(=O)c1ccc(NC(=O)NCc2ccccn2)cc1Cl +CCc1ccccc1-n1nnc(CO)c1C1CCCO1 +COCC(NC(=O)c1ccc(F)cc1Cl)C(N)=O +N#Cc1ccsc1NC(=O)CSc1nc2ccccc2o1 +CC(=O)c1ccc(C2NCCc3c(N)cc(F)cc32)s1 +O=C(NCCc1ccc(F)cc1F)C1CC2CCC1O2 +CN(C)c1nc(N(C)C)n(C(=O)Nc2ccc(Cl)cc2)n1 +CCOc1ccccc1C(=O)Nc1cnn(CC)c1 +CC(C)(C)CNC(=O)c1ncc(-c2ccncc2)o1 +Cc1ccoc1C(=O)OCC1CC(=O)N(C2CC2)C1 +CC(C)C(=O)Nc1nnc(C2CC(=O)N(c3ccc(Cl)cc3)C2)o1 +NC(=O)NC(CC(=O)NC1CCCc2ccccc21)c1cccs1 +COc1ccc(OC)c(CC(=O)NCC2Cc3ccccc3O2)c1 +CC(C)CNC(=O)c1nc(-c2c[nH]c3ccccc23)no1 +Cc1nn(C)c(C)c1CC(C)C(=O)N1CCOCC1C1CC1 +CCOc1ccc(N(CC(=O)OC)S(C)(=O)=O)cc1 +CC(=O)N(C)c1ccc(NC(=O)COc2ccc(C)cc2)cc1 +CCOC1CCCN(S(=O)(=O)c2ccc(=O)[nH]c2)C1 +Nc1nccnc1C(=O)Nc1cccc(OCc2cccnc2)c1 +Cc1nc2ccccc2nc1OCc1nc(N)nc(N(C)C)n1 +CCn1cnnc1CNC(=O)NC(C)c1ccco1 +CC(C)CCCNC(=O)c1ccc(S(C)(=O)=O)cc1 +O=C(Nc1ccc2nc(C3CC3)oc2c1)NC(CO)c1ccccc1 +CCNC(=O)c1ccc(C)c(NC(=O)Cc2ccc(F)c(F)c2)c1 +CC1CCN(S(=O)(=O)c2ccc3c(c2)NCCO3)CC1 +CCSc1ccccc1C(=O)Nc1nnc(-c2cccnc2)o1 +CCCC(=O)NC(c1ccc(OC)cc1)c1nccn1C +CN(C)c1cccc(C(=O)N2CCN(c3ncccn3)CC2)c1 +CCC(C)N1CC23C=CC(O2)C(C(=O)OCc2ccccc2)C3C1=O +CN(CCc1ccccn1)C(=O)Nc1nnc(C2CC2)s1 +N#Cc1cccc(Cl)c1N1CCCC(CO)C1 +Cc1cccc2c1CC1(Cc3c(C)cccc3C1=O)C2=O +COc1ccc2c(C(=O)NCCc3ccco3)cc(=O)oc2c1 +c1ccc2[nH]c(CCn3ccnc3-c3ccc(-c4cc[nH]n4)o3)nc2c1 +O=C(c1ccc(O)cc1)C1CCN(C(=O)NCC2CCOC2)CC1 +CC1CCN(C(=O)NC(c2nc(C3CC3)no2)C(C)C)C(C)C1 +O=S1(=O)N=C(NCc2ccncc2)c2ccccc21 +CCc1nn(C)c(CC)c1CNC(=O)Nc1nc(C)ccc1OC +CCC(=O)N1CCC2(CC1)NC(CC(C)C)C(=O)N2C(C)C +Cn1c(N2CCC(C(=O)NCC3CC3)CC2)nc2ccccc21 +C=CCN(CC=C)C(=O)c1cnc(CCC)nc1N +CN(C)C(=C1N=C(c2ccccc2)OC1=O)N1CCOCC1 +COC(=O)C1CCN(C(=O)NCCOc2ccc(C)cc2)CC1 +Cc1cc(Oc2ncccn2)ccc1NC(=O)NCC1CC1 +CCc1c(C)nn(Cc2ccc(Cl)cc2N)c1C +COC(=O)c1n[nH]c2ccc(Br)cc12 +CC1(C)CN(C(=O)c2cccc(N3CCCC3=O)c2)CC1(O)C1CC1 +O=C(Nc1cnc(N2CCCC2)nc1)c1c(F)cccc1F +Cc1nccc(CNc2nn3cc(-c4ccc(F)cc4)nc3s2)n1 +Cc1c(C(=O)N(Cc2ccco2)C2CC2)cnn1C +Cc1ccccc1N(CC(=O)N(C)C)S(C)(=O)=O +COC(=O)C(NC(=O)c1cc(C)nn1C)c1ccc2ccccc2c1 +COC1(CNC(=O)Cc2csc(C(C)C)n2)CCC1 +COc1ccc(C)cc1-c1cn(-c2cc(N)ccc2C)nn1 +CCC(C(=O)NC(C)C(C)n1cncn1)N1CCCC1=O +N#Cc1ccc(C(=O)NC(C#N)C2CCCCC2)cc1 +COC(=O)C1CCCCN1C(=O)C(C)NC(=O)c1ccco1 +Cc1ccc(-c2cnn3c(NCCCn4ccnc4)cc(C)nc23)cc1 +C#CC1(NS(=O)(=O)c2ccccc2)CCCCC1 +CCC(=O)NCC(=O)NCc1ccc(-c2nc3ccccc3[nH]2)cc1 +CN(CC(=O)N1CCOC(C)(C)C1)S(=O)(=O)c1ccccc1 +CC1CN(C(C)C(=O)N(C)CCC#N)c2ccccc21 +COc1ccc(NC(=O)Nc2cnccc2C)cc1OC(F)F +CC(=O)Nc1cccc(NC(=O)COc2nncc3ccccc23)c1 +CCOC(=O)c1cc2cc(C(=O)Nc3nncs3)ccc2[nH]1 +Cc1cccc(C(=O)Nc2nc(CC(N)=O)cs2)c1C +O=C(Cc1ccc(F)cc1)N1CCCC1Cn1nnc2ccccc21 +O=C(CCc1nc(-c2cccnc2)no1)Oc1cccc(F)c1 +CCC(C)(C)C(=O)NCc1cc(OC)c(O)c(OC)c1 +COc1ccc(NC(=O)c2cc(C3CC3)n(C(C)(C)C)n2)c(OC)c1 +Cc1cc(-n2cnnc2)cc(C)c1NC(=O)CC(C)C +Cc1occc1-c1nn(CC(=O)N2CC(C)CC(C)C2)c(=O)o1 +C#CCN1C(=O)C(Cc2ccccc2OC)Oc2cc(O)ccc21 +CC1CCCC(N(C)C(=O)c2cnn(-c3ccc(F)cc3)n2)C1 +N#Cc1nnc2scc(-c3ccc4c(c3)OCCO4)n12 +Cc1cccc(-c2ccc(C(=O)NCc3nnc4n3CCC4)c(=O)[nH]2)c1 +O=C1Cc2cc(NC(=O)NCc3cccs3)ccc2N1 +COC(C)(C)c1noc(CNC(=O)c2ccc(C(F)(F)F)cc2)n1 +Cc1cc(C)n(CC2CN(CC(=O)Nc3cccnc3)CCO2)n1 +Cc1cc(C)nc(NC(=O)c2ccn(COc3ccc(F)cc3)n2)c1 +Cc1ccc(OCC(=O)Nc2ccc(CCO)cc2)cc1 +Cc1c(CO)nnn1CCOc1ccc(C(C)(C)C)cc1 +O=C(CSc1nnc(C2CC2)n1Cc1ccccc1)NC1CC1 +CNc1ncc(Br)cc1C(=O)NC1CCCC(C)C1 +CCCC(=O)Nc1nnc(-c2ccc(OC)cc2)s1 +O=C(NC1CC1)c1cccc(NC(=O)c2ccc(Cl)cc2F)c1 +CC(C)C(C)(C#N)NC(=O)CNc1cccc(F)c1F +CN(Cc1ccc(-c2ccccc2)cc1)C(=O)CS(=O)(=O)N(C)C +COC(=O)c1ccsc1NC(=O)CCNC(=O)c1cccs1 +Cc1nc2c(cc1C(=O)OC1CCCC1)c(C)nn2C +COc1ccc(-c2nc(C)sc2C(=O)Nc2nc[nH]n2)cc1 +O=C(COc1ccccc1)NCc1noc(-c2cccs2)n1 +CCCNC(=O)CN1CCN(C(=O)c2ccc(C)s2)CC1 +Cc1cccc(Cc2nnc(NC(=O)N(C)Cc3ccoc3)s2)c1 +CCOCCC(=O)Nc1ccc(C(=O)NC2CCCC2)cc1C +O=C(Nc1ccc2c(c1)COC2)c1cc(F)cc(F)c1 +O=C(CCNC(=O)c1ccsc1)Nn1cnc2ccccc2c1=O +Cc1nn(C)c(C)c1C1CCCN1C(=O)c1cc(-c2ccco2)[nH]n1 +Cc1cc(NC(=O)Nc2cnn(CC(F)F)c2)c2ncccc2c1 +CC(C)Oc1ccc(CNC(=O)NC2CCc3cc(F)ccc32)cn1 +Cc1cc(CN(C)C(=O)c2nc(C)n(-c3ccc(F)cc3)n2)no1 +O=c1nc(NCCc2ccccc2)[nH]nc1Cc1ccc(F)cc1 +CC1COC(c2ccccc2)CN1C(=O)C1(C#N)CCCC1 +Cc1ccc(-n2nc(C)c(C(=O)N3CCC3)n2)c(C)c1 +COc1cc2c(OC)cccc2cc1C(=O)N1CCOCC1 +CCc1cc(C(=O)N(C)C2(C#N)CCC2)sc1C +COC(=O)c1cccn(Cc2ccc(F)c(F)c2)c1=O +CC(NC(=O)CN1CCCCCC1=O)c1ccc(-n2ccnc2)cc1 +Cc1nc(NC(=O)CN2CCOCC2)sc1-c1ccccc1 +COCCCNC(=O)c1cnc(C(C)C)nc1N +CCOc1ccc(CNC(=O)C2CC=CC2)cc1F +CCc1c(C(=O)NC2CCCC2C)cnn1-c1ccccn1 +CC(=O)Nc1nc2ccccc2n1Cc1ccccc1 +CCOc1c(OC)cc(CN2CCOC3(CCC3)C2)cc1OC +CCS(=O)(=O)c1ccc(C(=O)Nc2nc(C)cs2)cc1 +CNC(=O)C(C)n1nc(-c2ccc(OC)cc2)c(OC)cc1=O +c1ccc(Nc2nc(CSc3ncn[nH]3)cs2)cc1 +COC(=O)CSc1nc2c(c(-c3ccco3)c1C#N)CCC2 +N#CC1(NC(=O)CC(NC(=O)c2ccccc2)c2ccccc2)CCC1 +CSc1ccccc1C(=O)NCC1CCN(c2cnccn2)CC1 +O=C(Cc1cccs1)N1CCCC1(CO)Cc1ccccc1 +Cc1cc(C(=O)Nc2ccccc2SC(F)F)on1 +Cc1cccc(C(=O)N(CCC#N)Cc2cccnc2)c1N +Cc1cnn(CCCN2CCOC(c3ccc(Cl)cc3)C2)c1 +O=C(NCC1CCCN(C(=O)c2cccnc2)C1)c1ccco1 +COc1ccccc1CCC(=O)N1CCC(C)(O)C(O)C1 +CCn1ncnc1C1CC(=O)Nc2[nH]nc(C(=O)OC)c21 +O=C(CCCc1ccccn1)NCc1cccc(F)c1 +c1ccc(Cc2nnc(-c3ccc4c(c3)OCO4)o2)cc1 +COc1ccc(Cl)cc1CNC(=O)COc1ccccn1 +CCc1cc2c(c(C(O)c3ccco3)c1)NC(=O)C2C +O=C(NCCc1nc2ccccc2[nH]1)C1(n2cnnn2)CCCCC1 +CC(C)c1cc(C(=O)N2CCC(c3cccc(O)c3)CC2)n(C)n1 +CC(=O)Nc1ccccc1-c1nc(COc2ccccc2)no1 +Cc1cc(C(=O)N2CC3CCC(C2)N(CC2CCC2)C3=O)cs1 +Cc1cccc(NC(=O)C(C)Nc2ccc(N3CCCC3=O)cc2)c1 +Cc1oc(C(C)C)cc1C(=O)N1CC2CCC1CN(C(=O)N(C)C)C2 +O=C(Cc1nc(-c2cnccn2)n[nH]1)NCc1ccccn1 +CC(=O)c1ccc(S(=O)(=O)N(C)CC(N)=O)cc1 +CCc1nc2ccc(Br)cc2c(=O)o1 +COCCNC(=O)c1cc(OC)c(C)c(OC)c1 +O=C(NCC(F)(F)F)c1cccc(NC(=O)C2CCCO2)c1 +COCCCNC(=O)c1cc(S(C)(=O)=O)c(Cl)cc1Cl +COCC1(O)CCN(C(=O)c2n[nH]c3c2CCC3)CC1(C)C +O=C(NCCn1ccnn1)Nc1ccc2c(c1)oc1ccccc12 +Cn1c(C(=O)NCc2ccncc2)c(Cl)c2ccccc21 +CC(Oc1ccc(C(N)=O)cc1)C(=O)NCc1ccc(Cl)cc1 +CC(NC(=O)c1cccs1)c1nc(-c2ccc(F)cc2)no1 +O=C(Nc1ccc(N2CCNC2=O)cc1)c1ccccc1-n1cccn1 +O=C(NCC(O)c1ccc2c(c1)OCO2)C1CCCCC1 +CN(CCO)C(=O)c1cn(C2CC2)c2cccc(N)c2c1=O +CCCN(CCC)C(=O)c1ccc2c(=O)n(C)c(=O)n(C)c2n1 +Cn1cnnc1CNC(=O)Nc1cnn(CC(N)=O)c1 +NC(c1ccncc1)c1c(F)c(F)cc(F)c1F +C=CCC(C)NC(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +Cc1cc(C)n2nc(SCCCC(=O)c3ccc(F)cc3)nc2n1 +CC(=O)NC12CC3CC(C1)CC(C(=O)N(C)C)(C3)C2 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1cn[nH]c1 +Cc1cccc(NC(=O)c2cc(Cl)c3c(c2)OCO3)c1C#N +CCc1n[nH]c(SCC(=O)NC(C(=O)NC)c2ccccc2)n1 +CCOCCCNC(=O)C1=C(C)C(=O)OC12CCN(CC)CC2 +Cc1cc(C)n(CC(C)CNC(=O)N2CCOCC2CC(C)C)n1 +COc1cccc(N2CCN(c3cc(C)nc4cc(C)nn34)CC2)c1 +CC1COc2ccc(S(N)(=O)=O)cc2N(C)C1=O +Cc1ccccc1C1CCCN1C(=O)NCc1cccc(C(N)=O)c1 +CC(=O)Nc1scc2c1nnc1c(-c3ccccc3)c(C)nn12 +CN1CC2(CCCN(c3nc(-c4ccccc4)no3)CC2)OC1=O +COC(=O)C(NC(=O)c1sc(C)cc1OC(F)F)C(C)C +CCCC(=O)Nc1ccc(C(=O)Cn2cnc(C#N)c2C#N)cc1 +COC(=O)C(C)NC(=O)c1cc(C)c(OC(F)F)c(C)c1 +Cc1ccc(C(=O)N(C)CC(O)C2CC2)cc1NC(=O)OC(C)(C)C +CC(C)n1cnc2cc(CNC(=O)c3cccc(C#N)c3)ccc21 +CC1(C)COCCN1C(=O)c1ccc(C(N)=O)nc1 +Cc1ccc(C(=O)N2CCc3ccc(S(N)(=O)=O)cc32)s1 +COc1cccc(N2CCCC(NC(=O)NCC(C)CC(C)O)C2)c1 +CCOCCCNC(=O)c1ccc(C(N)=O)cc1 +COc1ccccc1CC(=O)Nc1c(C)nn(C)c1C +Cc1nnnn1-c1cccc(NC(=O)NC2CCC(C)CC2)c1 +CC(C#N)CN(C)CC(=O)NC(C)c1ccc(Br)cc1 +CC(C(=O)Nc1cccc(F)c1)n1nc(-c2ccccc2)ccc1=O +Cc1nc2c(cc1C(=O)N(C)Cc1nc3ccccc3[nH]1)c(C)nn2C +Cn1cc(CCC(=O)Nc2cc3c(cc2Cl)OCCCO3)cn1 +COc1ccc(F)cc1NC(=O)NCc1ccnn1C +COCC(=O)Nc1nn2c(C3CCCCC3)nnc2s1 +CC(NC(=O)C1CCCO1)c1ccc2c(c1)NC(=O)CO2 +O=C(COc1ccc(N2CCCC2=O)cc1)OCC(F)(F)F +Cc1ccc(OCC2CCCN(C(=O)c3c[nH]c(=O)[nH]c3=O)C2)cc1 +O=C(NCC#CCN1CCOCC1)c1nc2ccccc2s1 +Cc1cc(C)c(C(=O)Nc2nc3ccccc3s2)c(=O)[nH]1 +COc1ccc(N)c2c1N(C(C)C)S(=O)(=O)C2 +CCCc1cc(C(=O)N2CCOCC2c2c(C)nn(C)c2C)[nH]n1 +O=C(CC1CCCC1)Nc1ccccc1C(=O)NCc1ccco1 +O=C(Nc1ccc(O)cc1)c1cc(Cl)ccc1O +O=c1c(=O)n(-c2ccccc2)ccn1Cc1cccc(C(F)(F)F)c1 +CCN1CC(C(=O)N(CCOC)Cc2ccccc2)CC1=O +COc1ccc(Br)c(CNC(=O)c2ccncc2)c1 +CC(C)C(=O)N1CCCC1C(=O)Nc1ccc2ccccc2c1 +COc1ccccc1CN(C)CC(=O)c1cc(C)n(C2CC2)c1C +O=C(NCc1ccc(C(=O)N2CCCC2)cc1)c1ccncc1 +COc1ccc(CNC(=O)NCC2(c3ccccc3)CCC2)cc1O +COCCN(CC(F)(F)F)C(=O)c1cnc(-c2ccccc2)s1 +O=C(NCCC1=CCCCC1)C1COCC(=O)N1Cc1cccs1 +CCCCN(C)S(=O)(=O)N1CCN(Cc2nc(C)c(C)o2)CC1 +CC(=O)Nc1ccc(O)c(C(=O)NCC(C)(O)c2ccc(F)cc2)c1 +CCOc1cc(CNc2ccc3c(c2)COC3)ccc1OC +c1ccc2nc(SCc3cn4ccsc4n3)cnc2c1 +CCn1cc(C(=O)Nc2c(C(=O)OC)nn(C)c2C)c(C)n1 +O=C(Cn1ccc(-c2ccc(F)cc2)n1)N1CCC2(CC1)OCCO2 +O=C(c1cccc(-c2ccoc2)c1)N1CCOc2ccncc21 +O=C(CCc1nc2ccccc2s1)NC1CCCc2ccccc21 +COc1cc2c(cc1F)C(c1cnoc1C)NCC2 +CC(C)C(C)NC(=O)COc1cccc(C(F)(F)F)c1 +CN(C(=O)Nc1cn[nH]c1)C1CCCc2ccccc21 +C=CCCC(C)Nc1ccc(NS(C)(=O)=O)cc1 +COCCC(=O)NCc1ccc(-c2nc(C(C)C)cs2)cc1 +Cc1cc(C)n(-c2ncnc(N3CCc4ccccc43)c2N)n1 +CN(Cc1ccco1)C(=O)CNc1ccc(-n2cncn2)c(Cl)c1 +Nc1n[nH]c(Cc2ccc(Cl)cc2)c1-c1ccccn1 +CS(=O)(=O)NC1(c2ccc(Br)cc2)CCOCC1 +O=C(Cn1nnc(-c2ccccc2)n1)Oc1ccccc1 +Cc1cc(O)c(C(C)C)cc1NC(=O)c1cccc(-n2cccn2)n1 +O=C(c1ccccc1)N1CCN(Cc2ccccc2OCCO)CC1 +COc1ccc(C(C)NC(=O)c2nnc3ccccc3n2)cc1 +Cc1n[nH]c(SCc2cccc(C#CCO)c2)n1 +Cc1nc(-c2ccsc2)ccc1C(=O)NCCNS(C)(=O)=O +Cc1ccc(CNC(=O)c2ccc(NC(=O)C3CC3)s2)cc1 +CCc1cccc(CC)c1NC(=O)N(C)Cc1nccn1C(F)F +CN(c1ncccn1)C1COC2(CCN(C(=O)c3ccnnc3)C2)C1 +CCOC(=O)N1CCC(C(=O)Nc2nc(C(C)=O)cs2)CC1 +Cc1nn(C)cc1S(=O)(=O)N(C)CC(=O)n1ccnc1 +Cc1oc(C)c(C(=O)NCc2cccc(OCC(=O)N(C)C)c2)c1C +Cc1csc(-n2nc(Cc3ccccc3)c3c2CCNC3)n1 +O=C(NCC(=O)N1CCCC1)c1c[nH]c2cccc(F)c12 +COC(=O)Cc1ccc(OCc2csc(C)n2)cc1 +CCC1CCc2c(C(=O)Nc3nnc(C)s3)csc2C1 +CNc1nc(-c2ccc3c(c2)CCN3C)c(C(C)=O)s1 +COc1ccc(F)cc1NC(=O)c1cnc(-c2ccccn2)s1 +COc1ncccc1N(C)C(=O)c1nn(CC(C)C)cc1C(F)F +Cc1cc(NC(=O)CN2CCN(C(=O)C3CC=CCC3)CC2)no1 +Cc1nnc(O)nc1SCC(=O)Nc1ccccc1Cl +Clc1ccc(-c2noc3ncnc(NC4CC4)c23)cc1 +CC(=O)c1cccc(NC(=O)c2sc(N)nc2-c2ccccc2)c1 +CCC(NC(=O)c1ccnc(-n2cnnc2)c1)c1ccccc1 +Cc1noc(C2CC2)c1NC(=O)CNC(=O)COc1ccccc1 +CCc1nc(C2CCCN2C(=O)CCc2ccc(C3CC3C)o2)no1 +Cc1ccc(N)cc1NC(=O)CCOC1CCCCC1C +CC(C)CNC(=O)C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +COCCNC(=O)NCCc1ccn(-c2ccccc2)n1 +CCC1=NS(=O)(=O)c2cccnc2N1c1ccccc1 +O=C(c1ccc2ccccc2c1O)N1CCN(c2nccs2)CC1 +COc1ccc(C(=O)NCC#Cc2ccc(NC(C)=O)cc2)cc1 +O=C(Cn1cc(C2CC2)nn1)N1CCn2cccc2C1c1ccccc1 +NC(=O)c1ccccc1OCC(=O)N1CCCC1c1ccsc1 +CC1=C(C(=O)Nc2ccc(C)cc2C)C(c2ccc(C)o2)NC(=O)N1 +CC1CN(C(=O)CCC(=O)c2ccccc2)c2ccccc21 +COC(=O)CN(c1ccc(Cl)cc1)S(=O)(=O)c1ccccc1 +CCN(C)C(C(=O)Nc1cccc(Cn2cncn2)c1)c1ccccc1 +COc1cccc(-c2cc(C#N)nn2CC(C)C)c1 +Cc1ccc(C)c(S(=O)(=O)Nc2cc(N)ccc2C)c1 +COc1cc(CNC2COc3c(cccc3OC)C2)ccc1F +CCn1c(=O)c(C(=O)NCCCOC)nn(-c2cccc(C)c2)c1=O +O=c1cc(NCc2cccs2)[nH]c(=O)n1Cc1ccc(F)cc1 +CCCNC(=O)CNC(=O)CCn1ccc2ccccc21 +CCC(NC(=O)NC(C)Cn1nc(C)cc1C)c1nccs1 +CN(C(=O)c1ccc(NCc2ccncc2)cc1)C1CCOCC1 +COc1c(Br)cccc1CCNC(=O)C1(C#N)CCC1 +CC(C)Nc1nnc(-c2c3c(nn(C)c2=O)CCC3)s1 +CCNC(=O)CCc1ccc(S(=O)(=O)N(C)C)cc1 +CC(CNC(=O)N1CCOC(C)(C)C1)c1nc(-c2ccccc2)no1 +CCN(C(=O)C(C)Oc1cccc(N)c1)c1ccccc1 +CCOc1ccccc1NCC(=O)Nc1cc(C)nn1C(C)(C)C +O=C(Nc1ccc(Cl)cc1Cl)c1ccnnc1 +COc1cccc(NC(=O)c2cc(Cl)c(OC)c(OC)c2)c1 +CC(NC(=O)CC(C)(C)C)c1ccc(S(C)(=O)=O)cc1 +O=S(=O)(NCCn1ccnc1)c1ccc(Br)cc1 +COCC(=O)NC(C(=O)NC1CCCCCC1)C(C)C +Cc1nc(C2(NC(=O)c3ccc(C(=O)N(C)C)cc3)CCCC2)no1 +CNC(=O)CN1CCN(C(=O)CCc2ccc(OC)cc2)CC1 +CCc1ccc(OC)c(CC(=O)NCCCO)c1 +COC(=O)CN(c1cc(C)ccc1OC)S(C)(=O)=O +O=C(NCC(=O)N1CCc2sccc2C1)c1ccc(F)cc1 +c1ccc(-c2ncn(CC3CCOCC3)c2-c2ncc[nH]2)cc1 +COCCN(CC(F)(F)F)C(=O)Cc1csc(C)n1 +CCCN(C)C(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +COc1ccccc1-c1nnc(Cc2c(C)noc2C)o1 +C#Cc1cccc(NCc2nnc(C(C)(C)C)o2)c1 +CCCN(C)C(=O)Nc1cccc(OCCn2cccn2)c1 +O=C(CN1CCCCCC1=O)Nc1cccc(OC(F)(F)F)c1 +CCCNC(=O)CCNC(=O)NCc1cc(Br)cs1 +CC(C)(C)NC(=O)CC(C#N)c1ccc(Cl)cc1 +Cc1ccc(NC(=O)CCc2ccsc2)c(OCC(=O)N(C)C)c1 +O=C(CC1CC1)NCC1Cn2nnc(-c3ccccc3)c2CO1 +CN1CCN(C(=O)Cc2csc(-c3ccccc3)n2)CC1 +COc1ccc(NC(=O)c2cnn(C)c2C)cc1OC +Cc1ccccc1CC(C)NC(=O)CSc1ncn[nH]1 +COc1ccc2cc(CNc3cncnc3)ccc2c1 +C=CCNc1nnc(SC(C)C(=O)N2CCN(CC)CC2)s1 +C#CCN1CCC(C(=O)N2CCN(CCOC)C(=O)C2)CC1 +O=C(Nc1nc2c(s1)CNC2)c1c(F)cccc1Cl +O=C(CN1C(=O)Cc2ccccc21)c1ccc(F)cc1 +Nc1ccc2c(NCC3CCOC3c3ccccc3)ncnc2n1 +Fc1cc(F)cc(CNc2cnn(CC3CCCO3)c2)c1 +O=C(NCCOc1ccccc1F)Nc1cccnc1 +O=c1oc(-c2cccs2)nn1Cc1ccccc1Br +CCCCNC(=O)c1ccc(Br)c(F)c1 +CC(=O)Nc1cc(C(=O)NCCNC(=O)C(C)C)ccc1C +O=C(c1ccnnc1)N1CCN2CC(Oc3ccccc3)CC2C1 +Cc1noc(COC(=O)CCOc2c(C)cccc2C)n1 +Cn1nc2n(c1=O)CCN(Cc1ccc(C(N)=O)cc1)C2 +O=C(Nc1ccc2nc[nH]c2c1)c1ccc2c(c1)OCCCO2 +Nc1ncc(-c2nnnn2-c2ccccc2)c(-c2cccc(Cl)c2)n1 +CCCCc1nc(CS(=O)(=O)c2ccc(F)cc2)no1 +CC1CCN(C(=O)c2cccc3ncccc23)C(C)C1 +COc1cc2c(cc1O)CCNC2c1n[nH]c2ccccc12 +Cc1ccc(C(=O)Nc2nc(C3CC3)cs2)cc1C +CN(C)C(=O)N1CCC(Nc2cccc(-c3nccs3)c2)CC1 +CC(CC(=O)N1CCCS1(=O)=O)c1ccccc1C(F)(F)F +CCN(Cc1ccccc1)C(=O)Cn1cnc(N)n1 +O=C(CC1CCCN1C(=O)c1ccoc1)c1ccccc1 +COc1ccc(C)cc1-n1cnnc1Cn1nc(C)c(C)c1C +COC(=O)c1ccc2c(c1)CCN2C(=O)c1ccc(C#N)cc1 +Cc1ccc(OC(C)C(=O)Nc2c[nH]nc2C)cc1 +N#Cc1ccc(-c2noc(COc3ccc4ccccc4c3)n2)nc1 +CCOC(=O)CNC(=O)N1CCN(CC)c2ncccc21 +Cc1ccc(C(=O)C2CCCN2C(=O)C(C)C)cc1C +COc1cc(C(=O)N2CC(C)CCCC2C)sc1S(N)(=O)=O +C=CCOc1cccn(Cc2ccc(C#N)cc2)c1=O +N#Cc1cccc(CNC(=O)NCCCOc2ccccc2)c1 +CCCOC(=O)c1cc(-c2cc(C)cc(N)c2OC)n[nH]1 +CCCCS(=O)(=O)N(C)c1cc(N)ccc1Cl +CCc1onc(C)c1NC(=O)c1cc(-c2ccccc2Cl)[nH]n1 +O=C(CCCn1cncn1)NCCc1c(Cl)cccc1Cl +O=C(NCc1cc(Cl)ccn1)Nc1ccn(Cc2ccccc2)n1 +CCOc1cc(F)ccc1NC(=O)c1cc(C)n(CC)c1C +COCCn1c(-c2cccc(OC)c2)ccc(C#N)c1=O +CC(C)CC(NC(=O)c1c[nH]c2ccccc12)c1nnc2ccccn12 +CCOC(=O)c1ccc(CC)nc1-c1ccccc1 +CCCNC(=O)CCCC(=O)c1ccc(Br)cc1 +Cn1ncc2c(N3CCCC(C(=O)NC4CCCCC4)C3)ncnc21 +O=C(NCc1ccccc1Cl)c1cn(-c2cccc(Cl)c2)nn1 +Cc1ccc(OCC(=O)Nc2ccccc2SCC(N)=O)c(C)c1 +COc1ccc(C)cc1S(=O)(=O)N1CCCCC1 +CC(C)C(=O)Nc1nnc(SCc2cccc(F)c2)s1 +CCn1nc(C)c(NC(=O)Cn2cc(Br)c(C)n2)c1C +CC(Nc1cnn(CC(N)=O)c1)c1ccc(F)cc1 +O=C(Cc1ccsc1)N1CCC(Cn2cc(CCO)nn2)CC1 +COc1c(C)cccc1C(=O)NCCNC(=O)c1cccs1 +COc1ccc(CN(C)C(=O)Nc2cccc(Cl)c2)cc1OC +Cc1cccc(OCC(=O)N2CCN(Cc3cccc(F)c3)CC2)c1 +O=C(NC1C(c2cncnc2)CC(O)C1O)c1cncnc1 +COc1cccc(OCCc2ccc(F)c(C(N)=O)c2)c1 +O=C(CCNC(=O)c1cccnc1-n1cccn1)NC1CCCC1 +CCOC(=O)Cn1nc(-c2ccccc2)c2ccccc2c1=O +Cc1cc(C(=O)N2CCC(C(=O)c3cc(F)ccc3F)CC2)[nH]n1 +Cn1cnc2cc(CNC(=O)c3ccc(F)cc3)ccc21 +Cc1cccc(N(C)C(=O)Cn2ncc3c2-c2ccccc2OC3)c1 +Cc1ccc(N2CC(C(=O)NCCCn3cncn3)CC2=O)cc1 +CCCn1nccc1C(=O)Nc1cc(C)cc(C)c1 +CCOc1cc(C)ccc1NC(=O)Cc1csc(C)n1 +COc1cccc(COC(=O)C2CCOCC2)c1 +CCC(=O)Nc1nc(-c2ccc3c(c2)CCC(=O)N3)cs1 +CCN(CCC#N)C(=O)COc1ccc(C(F)(F)F)cc1 +Cc1nc(C(C)C)sc1C(=O)NCC(C)(C)N1CCOCC1 +CCOc1ccc(S(=O)(=O)Nc2ccc(N)cc2Cl)cc1 +O=C(Cc1csc(NC(=O)C2CCCC2)n1)NCc1ccccn1 +Cc1cc2nc(C)n(CC(=O)Nc3cccc(C#N)c3)c2cc1C +O=C(NCCCC1CCCC1)NCC(O)c1ccc(F)cc1 +COCC(=O)Nc1ccc2oc(C(=O)OC)cc(=O)c2c1 +Cn1nc(C(F)(F)F)cc1C(=O)NC1CCCCCC1 +Cc1ccc(NC(=O)N2CCCCC2CCO)cc1 +CCn1c(SCC(=O)Nc2nccs2)nnc1-c1ccoc1C +O=C(Nc1nncs1)c1ccc(C(F)(F)F)nc1 +Cc1nnc(COc2ccc(Br)cc2Cl)o1 +COC(=O)C1CC(O)CN1Cc1cnc(C(C)(C)C)s1 +COc1ccc(C2CCCN2C(=O)c2ccc(-n3ccnn3)cc2)cc1 +O=c1[nH]c(CCc2ccccc2)nc2ccccc12 +O=C(Cc1ccc(S(=O)(=O)N2CCCC2)s1)N1CCC1 +C=CCn1c(C)nnc1SCC(=O)N(C)Cc1ccc(C)o1 +CCCCn1c(CC#N)nc2cc(OCC)ccc21 +Nc1cc(C(=O)N2CCCCC2CCO)ccc1Cl +CCc1cc(C#N)c(NC(=O)c2cnc3cc(C)ccn3c2=O)s1 +CC(CO)NC(=O)c1ccc2nc(-n3cccc3)sc2c1 +CCn1cc(CN(CCO)Cc2cccnc2)cn1 +NC(=O)c1cc(Cl)ccc1NC(=O)Cn1c(=O)oc2ccccc21 +CC(C(=O)NC(c1ccccc1)c1ccccn1)c1ccsc1 +COc1cc(OC)c(OC)cc1CN1CCOC(C)C1C +CN(CCC#N)C(=O)c1cc(Br)cc2ccccc12 +CC(=O)N1CCc2cc(S(=O)(=O)Nc3ccc(C)cc3C)ccc21 +NC(=O)CNC(=O)c1ccc(OCC(F)(F)C(F)F)nc1 +CN(Cc1ccc(-c2ccc(Cl)cc2)o1)Cc1nnnn1C1CC1 +Nc1ccc(C(=O)Nc2cc(F)cc(F)c2)c(Cl)c1 +CCC(C)Nc1cc(OCC(C)C)nc(C2CC2)n1 +CCC(=O)NCC(=O)Nc1cnn(C(C)(C)C)c1 +CCc1sc(C(N)c2ccc3cc[nH]c3c2)nc1C +CCc1cc(C2CCCN2S(=O)(=O)c2cccc(Cl)c2)on1 +Cc1cc(C(=O)CCC(=O)N2CCOCC2C2CC2)c(C)s1 +COc1ccccc1C(=O)N1CC2CC1CC2NS(C)(=O)=O +CN(Cc1cccs1)C(=O)COc1ccc2c(c1)CCC2 +CC(=O)N1CCC(c2cccc(Oc3ccccc3)n2)CC1 +CCOc1ccc(C2(CNC(=O)N3CCCC3)CCOCC2)cc1 +Cc1cc(CN(C)C(=O)CCSc2nnnn2C)no1 +CCN(CC)C(=O)c1nc(-c2cccs2)n(-c2ccccc2)n1 +Cc1cc(=O)c(C2NCCc3cc(Cl)c(O)cc32)c[nH]1 +Cc1nnc(CN2CCCCC2CCN2CCOCC2)o1 +CC(=O)Nc1cccc(C2NCCc3ccc(C)c(F)c32)c1 +CS(=O)(=O)c1ccc(C(O)Cn2nnc(-c3ccccc3)n2)cc1 +CC(CCCO)NC(=O)NC1(C)Cc2ccccc2C1 +CC(C)(C)NC(=O)CNC(=O)COCC1CCCO1 +COCCNC(=O)Cc1csc(Nc2cccc(C)n2)n1 +CNC(=O)CCOC(=O)c1c[nH]nc1-c1ccc(F)c(Cl)c1 +Cc1cc(C)n(CCCNC(=O)NCc2ncn(C)n2)n1 +COc1ccc(C(=O)NC(C)C#N)cc1Br +Cc1[nH]c2ccccc2c1C(=O)N1CCC(C(N)=O)C1 +COc1ccccc1CN(C(=O)Cc1noc2ccccc12)C1CC1 +CN(c1ccc(OCc2ccc(F)cc2)cc1)S(C)(=O)=O +Cc1cnc(N2CCn3cc(CN(C)Cc4cccnc4)nc3C2)nc1 +O=C(Nc1ccc2c(c1)OCO2)C1CSc2nccc(=O)n2C1 +CC(C)NS(=O)(=O)c1cc(C(=O)NCC2CC2)ccc1F +CC(=O)c1cccc(NC(=O)CNC(c2ccccc2)c2ccoc2)c1 +CCCc1nc2sc3c(c2c(=O)n1N)CC(C)(C)OC3 +O=C(CCNC(=O)c1cccs1)Nc1ccc(-n2cnnn2)cc1 +COC(=O)c1ccc(C2CCN(C(=O)C3CC3)CC2)cc1 +CCOc1ccc(F)c(C(=O)NC(CCO)C(C)C)c1F +CCOC(=O)CSc1nc(C)c(CC)c(C)c1C(N)=O +O=C(Cn1cnc2ccccc2c1=O)Oc1ccc(-n2cnnn2)cc1 +CN(Cc1ccccc1)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +COc1ccc(C(=O)N(C)CCC(C)C)cc1Br +Nc1cccc2ccc(CC(=O)NCC3CCCO3)nc12 +CCC(=O)c1ccc(OCC(=O)NC(C)C(C)C)cc1 +CCCCOC(=O)C(C)Sc1nc(C)c(C)o1 +O=C(c1ccc(F)cc1)N1CCCC1c1cccnc1 +CCn1c(-c2cc(C)ccc2OC)ccc(C#N)c1=O +COC(=O)c1sccc1NC(=O)C1CC1(Cl)Cl +O=C(Nc1ccc(Br)cc1F)N1CCOCC1C1CC1 +Cn1cc(-c2cnc(-c3cccnc3)nc2)cc1C(=O)NC(C)(C)C +CC(C)C(=O)N1CCC(C(=O)N(C)c2ccc(F)c(F)c2)CC1 +CC(CO)C(C)NC(=O)N1CCCc2cc(F)ccc21 +CC1c2ccsc2CCN1C(=O)C1Cc2ccccc2O1 +O=C(NCCO)c1nn(-c2ccccc2F)c2c1CCC2 +COc1cccc(-c2nnn(CC(=O)Nc3ccc(C)c(F)c3)n2)c1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1cc2ccccc2c(=O)[nH]1 +CC1CCN(C(=O)CCCc2cccs2)C(C)C1 +O=C(Nc1cnccn1)c1cc(F)c(Cl)cc1F +CCC(=O)Nc1cccc(NC(=O)NC(C)CC)c1 +O=C(NCCc1nc(-c2cccs2)c[nH]1)c1c(F)cccc1Cl +COc1ccc(C(O)CNCc2cccnc2)cc1C(C)(C)C +COc1ccc(Cc2nnc(SC)n(N)c2=O)cc1OC +O=c1cc[nH]c(C2NCCc3cc(F)cc(F)c32)c1 +CN(Cc1cccc(C#N)c1)C(=O)Nc1ccc(F)c(F)c1 +CCCCCNC(=O)CNC(=O)c1ccc(C)cc1 +CS(=O)(=O)N1CCN(c2ccccc2-n2cnnc2)CC1 +O=C(c1ccnnc1)N1CCOC2CC(COc3ccccn3)CC21 +Cc1cn2nc(NCc3sccc3C)sc2n1 +Cc1ccc(C(=O)CSc2ccc(N)cc2)cc1 +CCCN(CC(=O)NC)C(=O)c1ccc(Br)cc1O +O=C(CNC(=O)C1CCCC1)NCCc1ccc(F)cc1 +Cc1ccc2c(c1)CCCN2C(=O)c1ccc(Cn2cncn2)cc1 +CC1CCN(C(=O)Cn2ncc3cccn3c2=O)CC1 +CCOC(=O)c1sc(NC(=O)C2(C#N)CCCC2)cc1C +C#CCOC(=O)c1ccc(-c2cc(N)ccc2OC)o1 +Cc1ccc(F)cc1NC(=O)C1CCN(c2cnccn2)CC1 +NC(=O)NCCCCC(=O)Nc1ccc(C(F)(F)F)cc1 +COc1ccc(C(C)NC(=O)Cn2cccnc2=O)c(OC)c1 +CC#CC(=O)NC(CCn1cncn1)c1ccccc1 +Cc1nn(C)cc1C=C1CC(=O)n2c1nc1ccccc12 +CC(C)c1ocnc1C(=O)N1CCC(C(O)c2cccs2)CC1 +CCOc1ccc(C(=O)NC(C)C(=O)N2CCCCC2)cc1 +CCc1nsc(N2CCN(Cc3ccc(F)cc3F)CC2)n1 +Cc1c(S(=O)(=O)Nc2cccc(F)c2)cnn1C +Cc1cc(CCNC(=O)C23CC4CC(CC(C4)C2)C3)on1 +CC(C)CCNS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +CCc1ccc(NC(=O)c2cc(-c3cccnc3)on2)cc1 +CCC(C)(C)NC(=O)CSc1nncc2c1[nH]c1ccc(F)cc12 +Cc1ccc2[nH]cc(CCNS(=O)(=O)c3c(C)noc3C)c2c1 +CC(c1ccc(F)cc1)N(C)S(=O)(=O)c1ccccc1F +CCn1ncc(-c2cc(C(F)(F)F)n3nc(C)c(Cl)c3n2)c1C +COCCOc1cccc(NC(=O)Nc2cc(F)ccc2OC)c1 +N#Cc1ccc(NCC(=O)Nc2ccccc2NCC(F)(F)F)cc1 +CCn1nc(C)c(NC(=O)c2ccc(-c3ccco3)o2)c1C +CCOC(=O)C1(NC(=O)CSc2ccncc2)CCCC1 +CC(C)(C)c1noc(COc2ccc(N3CCCC3=O)cc2)n1 +Cc1csc(CNc2ccc(C(N)=O)c(Cl)c2)n1 +CC(NCc1ncccn1)c1ccc(Br)cc1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)NC(C)c1ccncc1 +O=c1c(Cl)c(N2CCCC2)cnn1Cc1ccc(F)cc1 +CC(=O)N1CCC(C(=O)NCCCn2c(C)nc3ccccc32)CC1 +Cc1cc(OC(F)F)ccc1NC(=O)CSc1cn[nH]n1 +CSc1nc2ccc(NC(=O)c3ccncc3)cc2s1 +CCc1nc(CC(=O)Oc2cccc(C(=O)NC3CC3)c2)cs1 +C=CCn1c(C)nnc1SC(C(=O)Nc1ccccc1F)C(C)C +CC(=O)N(C)C(C#N)c1ccc(Cl)cc1Cl +Cc1c(C(=O)NCCNC(=O)C(C)(C)C)nc2ccc(Cl)cn12 +COCc1ccc(C(=O)NCCc2ccc(-n3cccn3)cc2)o1 +CN(C)c1c(Cl)cccc1NC(=O)c1scnc1C1CC1 +COC(=O)CN(C(=O)C(c1ccccc1)c1ccccc1)C(C)C +Fc1cc(Br)cc(Cn2ccnc2Cc2cccnc2)c1 +CC(C)CCOc1ccc(C(=O)NCc2ccco2)cc1N +Cc1cccc(-n2ccnc2S(=O)(=O)Cc2nc(C)cs2)c1 +COc1sc(CN2CCOCC2C2CC2)cc1Br +CC(C)(C)n1cc(CNCCc2cc(F)cc(F)c2)cn1 +c1ccc(-c2nnc(CNc3ncccn3)o2)cc1 +CCOc1cc(C)c(C(C)C)cc1S(=O)(=O)N1CCOCC1 +Cc1cc(C(=O)Nc2cc(C#N)ccc2O)c(C)n1C1CC1 +Cc1nc(SCc2nc3sc4c(c3c(=O)[nH]2)CCCC4)oc1C +COCCC1(C(=O)Nc2nn(-c3ccccc3Cl)cc2C)CCC1 +C=CCNC(=O)C(C)Sc1nnnn1-c1ccc(C)c(C)c1 +CCn1c(N)nc2cc(C(=O)NCCCc3ccccn3)cnc21 +Cc1noc(C)c1CSc1ncn(-c2ccccc2)n1 +O=C(Cc1csc(N2CCCC2=O)n1)NCCc1cccs1 +CCCc1cc(C(=O)N2CCN(c3ccccc3OCC)CC2)[nH]n1 +Cc1ccc(NC(=O)c2nc(-c3ccncc3)no2)cc1F +O=c1[nH]c2ccccc2c(=O)n1CCNc1cccc(Cl)c1 +COc1coc(COc2ccc3c(c2)OCO3)cc1=O +Cc1ccc2[nH]nc(C(=O)N(C)Cc3cccs3)c2c1 +O=C(CNc1cnc2ccccn2c1=O)Nc1ccc(F)cc1 +COc1ccc(NC(=O)c2cn(C)c3ccc(Cl)cc3c2=O)cc1 +Cc1ccc(S(=O)(=O)NCC(O)Cc2ccccc2)cc1 +CC(=O)C1C(c2ccco2)c2c(n[nH]c2C)CC1(C)O +Cc1cc(C(=O)N(C)CC(=O)NC(C)C)ccc1N +CCC(NC(=O)NC(C)COc1ccccc1F)c1ccncc1 +CC(C)C1CCN(C(=O)c2ccc(OCC(F)F)nc2)CC1 +Cc1cc(F)ccc1S(=O)(=O)Nc1cc(C(N)=O)cc(F)c1C +CCN(c1ccc(OCC(=O)N2CCOCC2)cc1)S(C)(=O)=O +Cc1nccc(C(=O)Nc2cc(Cl)c(O)c(Cl)c2)n1 +NC(=O)c1ccc(C(=O)Nc2ccc(Cl)cc2Cl)cn1 +COCCOc1ncccc1C(=O)Nc1ccc2oc(C)nc2c1 +CCCC(=O)Nc1cccc(C(=O)Nc2ccc(C(N)=O)cc2)c1 +Cc1c(NS(C)(=O)=O)cccc1C(=O)NCc1ccccc1 +O=C(COC(=O)c1ccc(O)cc1)NCc1ccc2c(c1)OCO2 +CC(C)Cc1nnc(C(C)Sc2nncc3ccccc23)o1 +O=C(COc1ccc2c(c1)CCC2)Nn1cnnc1 +N#CC1(c2ccc(C(F)(F)F)cc2)CCC(=O)CC1 +CC(C)CC(=O)NC(C(=O)NC(C)C(N)=O)C(C)C +COc1cc(OC)c(C(=O)NCc2cccs2)cc1OC +CC(C)c1cc(C(=O)OCC2CCN(CC(F)(F)F)CC2)n[nH]1 +CS(=O)(=O)NCC(=O)NCCOc1ccc(F)cc1 +O=C(NCCC1CCCO1)C1CC1c1ccc(Cl)cc1 +COC(=O)Nc1cccc(C(=O)NCc2ccccc2)c1 +CCc1ccc(OC)c(C2(C(C)=O)CCCCC2)c1 +C=CCCC1NCCc2ccc(O)c(Br)c21 +Cc1cc(-c2cc(C(=O)NCC(N)=O)c3c(C)noc3n2)c(C)s1 +Cc1ccccc1OCCCNC(=O)CC(F)(F)F +COc1ccc(-c2nc(CNC(=O)c3ccc(C#N)cc3)n[nH]2)cc1 +Cc1ccccc1CN(C)C(=O)c1scnc1C1CC1 +CC(C)OCCC(=O)Nc1ccc(C(=O)N2CCCC2)cc1 +CCCCc1nc2cc(C(=O)NCCc3cnn(C)c3)ccc2o1 +N#Cc1cccnc1N1CCN(C(=O)CC2CCCC2)CC1 +CCc1ccccc1OCC(=O)Oc1cccc(C(=O)NC)c1 +COc1ccc(F)c(F)c1C(=O)NC1CN(C(C)=O)CC1C1CC1 +Cc1cc(C)c(CNc2nc(-c3ccncc3)nc(C)c2C)c(=O)[nH]1 +CCn1cc(S(=O)(=O)N(C)c2cc(Cl)ccc2OC)cn1 +OC1CCCc2c1ccn2-c1cc(F)c(F)cc1F +Cc1cc(F)ccc1NC(=O)c1c(Br)c(C)nn1C +Cc1noc(C)c1CC(=O)Nc1ccc(Sc2nncn2C)cc1 +Cc1occc1-c1nnc(SCC(=O)N2C(C)CCCC2C)o1 +COc1cccc(OCC(=O)N(C(C)C)C(C)C)c1 +Cc1nc2cc(C(=O)NCCCNC(=O)OC(C)(C)C)ccc2n1C +c1ncc(-c2cc(NC3CCCC3)nc3[nH]ccc23)cn1 +CC(=O)NC(C)C(=O)OC1CCC(C(C)(C)C)CC1 +COc1cccc(CNC(=O)CC(c2ccccc2)n2cccc2)c1 +CS(=O)(=O)NCCNC(=O)c1nccnc1N +COc1ccc(NC(=O)N2CCOCC2)c(C(F)(F)F)c1 +Nc1ncn(CC(=O)Nc2cc(Br)ccc2F)n1 +CC(C)c1ccc2c(c1)C(O)C(N1CCC(=O)CC1)CO2 +Cc1ccc(-c2cc(N)ncn2)c(-n2cccn2)c1 +Cc1nn(CC(C)C)c(C)c1CC(=O)N(C)C1CCC1 +COc1ccccc1CC1CCCN(S(=O)(=O)N2CCCC2)C1 +CCN(Cc1ccc(C#N)cc1F)C(=O)c1ccc(C)[nH]c1=O +Cc1ccc(CNC(=O)N2CCC3(CC2)OCCO3)s1 +Cc1onc(-c2cccc(Br)c2)c1C(=O)NC(C)C +CC(C)CN1C(=O)C2(CCN(Cc3ccco3)C2)c2ccccc21 +Cc1ccc(O)c(S(=O)(=O)Nc2cccc(C(=O)NC3CC3)c2)c1 +Cc1cccc(C(=O)OC(C)C(=O)NCc2ccccc2)c1N +Cc1cc(NC2c3ccccc3CC2O)c(C#N)c(C)n1 +Cc1ccc(-c2nnc(SCC(=O)NC3CC3)o2)cc1 +C=CCOC1CN(C(=O)c2cccn2C)C2COCC12 +CCC(C)n1c(=O)[nH]c(=O)c2[nH]c(NCCO)nc21 +Cc1cnc(NC(=O)Cn2ccc3ccc(Cl)cc32)s1 +CCC(C(=O)NCCc1c(C)nn(CC)c1C)n1cccn1 +c1ccc(Cc2nc(-c3ccc4nc[nH]c4c3)n[nH]2)cc1 +CC(C)c1cccc(NC(=O)c2ccc(N3CCOCC3)nc2)c1 +COc1cc(Cl)c(S(=O)(=O)n2cnc(C)c2)cc1Cl +Cc1occc1-c1nnc(SCC(=O)N2C(C)CCCC2C)n1C +CCOC(=O)c1cn[nH]c1NC(=O)Nc1ccc(F)cc1 +CCCS(=O)(=O)N1CCCCC1C(=O)NCc1cscn1 +COc1ccc(F)c(NC(=O)Cn2nc(C)c3ccccc3c2=O)c1 +Cc1occc1NC(=O)NCCc1ccc(S(N)(=O)=O)cc1 +CC(C)C(NS(=O)(=O)c1cccc(C#N)c1)c1ccccc1 +CCc1noc(C(C)Sc2n[nH]c(C=Cc3ccccc3)n2)n1 +CSc1ccc(NC(=O)CCc2cnn(C)c2)cc1 +COCc1cc(C(=O)Nc2ccc(C)cn2)ccc1F +Cc1ccc2cc(C(=O)Nc3ccc(-n4cncn4)nc3)c(C)nc2c1 +Cc1ccc(NC(=O)C2CC2)c(-c2nc(C)no2)c1 +Nc1nc(-c2ccco2)ncc1C(=O)NCc1ccco1 +N#Cc1ccccc1C(N)c1nnc(-c2ccc[nH]2)o1 +CCCNC(=O)C(C)NC(=O)Nc1ccccc1-n1cccn1 +COC(=O)C1(NC(=O)c2ccc(C)n2C)CCCC1 +CCCS(=O)(=O)N1CCC(c2ccsc2)CC1 +CCN(C)c1ccccc1NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +CC(C)(C)c1ccc(NC(=O)CCNC(=O)c2ccco2)cc1 +O=C(c1cc(F)ccc1F)N1CCC(OCc2ccc(F)cc2)CC1 +CN(Cc1nnc2ccccn12)C(=O)Cc1c[nH]c2ccccc12 +COc1ccc(CCNC(=O)N2CC3CC2C(=O)O3)cc1 +CCN(CC)C(=O)c1ccc(NC(=O)C(C)NC(C)=O)cc1Cl +Cc1cccc(C(=O)N2CCCC(COc3cccc(F)c3)C2)n1 +Nc1cnc(COc2ccc(Cl)cc2)[nH]c1=O +NC(=O)c1ccc(NC(=O)c2cccc(F)c2F)cc1 +Cc1cc(NC(=O)Cn2ccc(-c3ccc(F)c(F)c3)n2)n(C)n1 +Cc1ccc(-c2nnc(CNCC3OCCc4ccccc43)o2)n1C +COc1ccccc1C(NC(=O)c1cc[nH]n1)c1ccccn1 +O=C(NCC(O)c1ccccc1Cl)C1CCOc2ccccc21 +CCC(Oc1ccccc1C)C(=O)Nc1cc(N)ccc1OC +Nc1ccccc1OCCn1nnc2ccccc21 +COc1cc(O)c2c(c1)C(C(O)c1ccc(C)cc1)NCC2 +O=C(NCc1ccc(Br)cc1)N1CCOCC1C1CC1 +O=C(COc1ccccc1O)N1CCN(Cc2cccs2)CC1 +Cc1cn(CC(=O)N2CCn3c(C)nnc3C2)c2ccccc12 +COc1ccc(NC(=O)NCCc2ccccn2)cc1F +Cc1cc(C)nc(SCc2nc3ccccc3n2C)n1 +COc1ccccc1NC(=O)c1nnn(-c2cccc(C)c2)c1N +CC(=O)N1CCc2cc(C(=O)OCC(F)F)ccc21 +CS(=O)(=O)N(CC(=O)N1CCOCC1)c1ccccc1F +Cc1cc(C)nc(NC(=O)NCC(CC(C)O)c2ccccc2)c1 +Cc1ccc(-c2nn(-c3ccccc3)cc2C(=O)NCCO)cc1C +CCc1ccc(NC(=O)Cn2ncn3c(cc4ccccc43)c2=O)cc1 +CCC1Oc2cccc(N)c2N(CC(=O)N2CCCC2)C1=O +N#CC(C(=O)Nc1ccccc1F)c1nccn1Cc1ccccc1 +Cc1ocnc1C(=O)N(C)Cc1cccc(OC(C)C)c1 +CCCC1CN(C(=O)c2ccc3c(c2)CCC3)CC1NC(C)=O +COc1cccc(C(=O)CNS(=O)(=O)c2cccs2)c1 +CCN(CC(O)c1ccc(C#N)cc1)CC(F)(F)F +CC(c1ccccn1)N(Cc1ccccc1)C(=O)c1ccc[nH]c1=O +Cc1cnc(CNc2nccc(-c3cccnc3)n2)cn1 +O=C(c1ccc2[nH]cnc2c1)N1CCCC1C1CCCC1 +N#Cc1cccnc1N1CCN(Cc2nnc3n2CCCCC3)CC1 +C#Cc1cccc(NC(=O)C2CC(=O)N(C(C)CCC)C2)c1 +CC1CCCC(CNC(=O)c2n[nH]c(=O)c3ccccc23)C1 +CCc1nc(Cc2nc(-c3ccc(C#N)cn3)no2)cs1 +Cc1ccc(C)c(CC(=O)NCc2noc(-c3scnc3C)n2)c1 +CN(C)c1ncc(Br)c2c(N)cc(F)cc12 +Cc1ccc(CNC(=O)Nc2cnn(C)c2)cc1F +CCOC(=O)N1CCC(NC(=O)Nc2cccc(Cl)c2)CC1 +Cc1ccccc1N1CC(c2nc3ccccc3[nH]2)CC1=O +CC(C)CC1COCCN1CC(=O)Nc1ccc2c(c1)OCCCO2 +CC(C)Oc1ccc(C(=O)Nc2ccc(CC(=O)N(C)C)cc2)cc1 +CCC(C)NC(=O)NCC(=O)Nc1ccc(F)c(F)c1 +O=C(CCn1c(=O)sc2ccccc21)NCc1ccc(F)cc1 +CN(CC(=O)NCC(=O)N1CCCCC1)C(=O)c1ccccc1 +NC(=O)C1CCN(C(=O)CN2CCN(c3ccccc3)C2=O)CC1 +O=C(Cc1ccccc1)N1CCCC(c2ccncc2)C1 +CN(C)C(=O)c1ccccc1NC(=O)c1ccccc1O +COc1ccc(S(=O)(=O)N(C)C(=O)c2ccc(Cl)cc2)cc1 +COC(=O)C1(NC(=O)C2CC(=O)N(C(C)C)C2)CCCCC1 +CCCOc1ccc(C(N)C(=O)NCC(C)O)cc1 +COC1C2=C(CCCC2)C(=O)N1CCc1ccccc1 +NC(=O)C1CCCN1c1nc(C(F)F)nc2ccccc12 +CCSc1nc(C)cc(C(=O)Nc2cccnc2)n1 +Cc1ccc(C(=O)NC2CC2c2ccccc2)cn1 +c1cc2c(cc1Nc1ccc3nnnn3n1)CCC2 +CCC(=O)NCC(=O)NCCc1ccc(C)cc1C +Cc1cnc(C(=O)NCc2ccc(-n3ccnc3C)c(F)c2)cn1 +Cc1cccc(CNC(=O)NCCc2nc(C(C)C)no2)c1 +Cc1ccc(NC(=O)C2(S(=O)(=O)c3ccc(Cl)cc3)CC2)cc1 +COC(=O)CCC(=O)Nc1ccc(Br)c(Cl)c1 +CCN(C)c1ccc(C(=O)NC(C)(C)c2nc(C)c(C)s2)cc1 +Cc1ccc(C(O)CNCc2cccnc2)cc1C +Cc1cccc(C(=O)N2CCN(C(=O)Cn3cnnn3)CC2)c1 +CNC(=O)C1CCCN(Cc2cnc(N3CCOCC3)nc2)C1 +Cc1cc(C(=O)N2CCC3(CC2)CC(OCC2CC2)CO3)sc1C +CC(=O)NC(C)(C)c1noc(-c2cc(C(C)C)[nH]n2)n1 +COCCCNC(=O)Nc1c(C)n(C)n(-c2ccccc2)c1=O +CCc1ccccc1CNC(=O)NC(C)C(=O)NC(C)(C)C +CCc1nc2ccccc2c(C(=O)OCc2nnc(C)o2)c1C +O=C(Nc1ccccc1C(=O)N1CCCC1)c1ccc2ccccc2n1 +O=C(c1ncoc1-c1ccco1)N(Cc1cccnc1)Cc1ccco1 +Cc1ccc(C(=O)NC(C)c2ccc(-n3cncn3)cc2)s1 +Cc1ccc(-c2nc(CC(=O)NCc3ccco3)sc2C)cc1C +CN(CCOc1ccccc1F)C(=O)c1ccc2c(c1)OCCO2 +CCc1cnc(NC(=O)NCCc2cccc(C(=O)OC)c2)s1 +CC1CN(c2nn3cc(-c4ccc(F)cc4)nc3s2)CCO1 +COC(=O)c1ccc(C(=O)Nc2cccc(F)c2)nc1 +Cc1cccc(NCc2nsc(N(C)C)n2)c1C(N)=O +CCc1noc(COc2cccc3c2NCCC3)n1 +CCS(=O)(=O)N1CCC(C(=O)N(CC2CC2)CC2CC2)CC1 +Cc1ccc(C(C)C)c(OCC(=O)Nc2ncc(C(N)=O)s2)c1 +Cn1c(C(=O)NC2CC2)cc2c(=O)oc3ccccc3c21 +CCCC(C)C(=O)NCc1c(C)nn(-c2ccccc2)c1C +Cn1ncc2c(Oc3cccc(C(F)(F)F)c3)ncnc21 +COCC(=O)N1CCN(c2nc(-c3cccc(Cl)c3)no2)CC1 +CCOc1ncccc1C(=O)N(C)c1cccc2ncccc12 +Cc1ccc(S(=O)(=O)N2CCN(Cc3ccncc3)CC2)cc1C +Cc1cc(=O)c(N)nn1-c1ccc(Br)cc1 +CCN1CCOC(CCNC(=O)c2cc(C(C)C)nn2C)C1 +CC1Oc2ccc(NC(=O)NCc3ccc(F)cc3)cc2NC1=O +O=C(NCc1ccccc1)c1nc(-c2ccc(Cl)cc2)no1 +COC(=O)c1cc(S(=O)(=O)NCc2cc(C)ccc2C)cn1C +CCn1c(C(=O)Nc2cccc(C(N)=O)c2)cc2sccc21 +CCn1ncc(NC(=O)Cn2cc(N)cn2)c1C(N)=O +NC(=O)c1ccccc1NC(=O)C1CC(=O)N(C2CCCCCC2)C1 +CC(C)CCC(=O)N1CCN(Cc2cc(C(N)=O)cs2)CC1 +O=C(Cc1coc(-c2ccc(F)cc2)n1)Nc1ccc2c(c1)COC2 +COC(=O)c1nccnc1C(=O)Nc1ccccc1N1CCOCC1 +c1ccc2cc(-c3csc(CN4CCOCC4)n3)ccc2c1 +Cc1cccc(N(CCC#N)S(=O)(=O)c2ccccc2)c1 +CCC(NC(=O)Nc1ccc(C(N)=O)c(C)c1)c1cc(F)ccc1F +CCOC(=O)c1cc(C(C)C)nc2c1c(C)nn2C +Cn1cc(CNC(=O)Nc2nnc(C3CC3)s2)cn1 +Cn1c(=O)n(CC(=O)NCc2ccccn2)c2cncnc21 +CC(Oc1ccccc1)C(=O)N1Cc2cncnc2C1 +COc1ccnc(NC(=O)c2cc(NC(C)=O)ccc2Cl)c1 +C#CCNC(=O)c1ccccc1NC(=O)c1cccc(-n2cccc2)c1 +COc1cc(C(C)=O)ccc1OCC(=O)Oc1ccc(C)c(C)c1 +O=C(NCCc1c[nH]c2cc(F)ccc12)c1ccc2cc[nH]c2c1 +CS(=O)(=O)c1ccc2nc(NC(=O)C3CCC3)sc2c1 +Cc1nnc(-c2cc(NS(C)(=O)=O)c(C)s2)o1 +Cc1ccc(C(=O)N2CC3(C)CC2CC(C)(C)C3)c(N)n1 +O=c1c2ccccc2nc(-c2ccco2)n1-c1ccncc1 +CCc1c(C(=O)Nc2ccc(NC(=O)c3ccccc3)nc2)cnn1C +COc1ccc(C(=O)Nc2c(C)c(C)nn2C)nn1 +c1ccc(CNc2ncnc3c2cnn3Cc2ccccc2)cc1 +CCC(Oc1ccccc1)C(=O)Nc1cc(C)ccn1 +Cc1ccc2nc(CSc3nnc(C)n3C3CC3)cc(=O)n2c1 +Cc1cc(NC(=O)CCc2ccccc2F)ccn1 +COc1cc(NC2CCN(C(=O)Cn3ccnc3)CC2)cc(OC)c1 +CCc1nnc(CNc2cc(S(=O)(=O)N(C)C)cc(C)c2C)o1 +Cc1cc2c(=O)n(CC(=O)Nc3ccc(C#N)cc3)cnc2s1 +COc1ccc(C(C#N)NC(=O)CC(C)C)cc1OC +NC(=O)c1cnc(NCC2Cc3ccccc3O2)c(Cl)c1 +Cc1ccc(C(=O)Oc2cccc(N3CCCC3=O)c2)s1 +Cc1ccc(NC(=O)N2CC(C)OC(C)C2)cc1S(C)(=O)=O +CCOc1cc2[nH]c(=O)n(C3CCCC3)c(=O)c2cc1OCC +CNS(=O)(=O)c1cc(NC(=O)C(O)c2ccccc2)ccc1C +Cc1c(C(=O)N(C)CCOCC2CC2)cnn1-c1cccc(Cl)c1 +CNC(=O)Cn1nnc(CO)c1-c1cccc(OC)c1 +CCn1nccc1C(=O)NCCOc1ccc(F)cc1 +Cc1ccc(N2CC(C(=O)NC(C)CO)CC2=O)c(F)c1 +CCCNc1ccc(C(=O)N(CC)C(C)CC)nn1 +Cc1ccc(CCNC(=O)C(C)c2c(C)n[nH]c2C)cc1 +CCN(CC)C(C(=O)NC1CCC2(CC1)OCCO2)c1ccccc1 +Cc1ccc(Cn2nccc2NC(=O)CCc2cc(Cl)cs2)o1 +CC(=O)Nc1ccc(OCC(O)CSc2ccc(C)cc2)cc1 +COc1c(C)cnc(CNC(=O)NCCc2c(F)cccc2F)c1C +CC(=O)Nc1ccc(C(=O)Nc2nnc(-c3cccnc3)s2)cc1 +O=C(c1cc(F)c(F)c(F)c1)N1CCC2(CCCC2)CC1 +CCCNc1nc(C)c(C(=O)Nc2ccccc2)s1 +COc1ccccc1N1CCN(C(=O)C(C)CC#N)CC1 +CC(=O)N1CCC(C(=O)OCc2ncc(-c3ccccc3)o2)CC1 +O=C(Nc1ccccc1)Nc1nccc(-c2ccccn2)n1 +Cc1nn(C)c(C)c1CNC(=O)c1cccc(-n2cnnn2)c1 +Nc1cc(C(=O)CCC(=O)N2CCc3ccccc32)ccc1F +O=C(c1ccc(=O)[nH]c1)N1CCN(C2CCc3ccccc3C2)CC1 +CS(=O)(=O)NCC(=O)Nc1cccc(C#Cc2ccccc2)c1 +CCOC(=O)c1cnc(SC)nc1Nc1cccc(NC(C)=O)c1 +COc1ccc(OC(=O)C2CCN(C(C)=O)CC2)cc1 +CC(=O)c1c(C)[nH]c(-c2csc(-c3cnccn3)n2)c1C +Cc1nc(N2CCCC(NC(=O)c3cnccn3)C2)[nH]c(=O)c1C +O=C(c1ccc[nH]c1=O)N1CC(c2nc(-c3ccncc3)no2)C1 +CCOc1ccc(CC(=O)NC2CCCn3nc(CC)nc32)cc1 +COc1cccc2c1CCNC2c1cccc(F)c1OC +Cc1ncnc2c1CCN(C(=O)c1ccccc1)C2 +O=C(CN1C(=O)CCCc2ccccc21)NCc1ccccc1F +COc1ccc(N2CC(c3nc(C)no3)CC2=O)cc1 +O=C(NCCc1ccncc1)Nc1cccc(NC(=O)C2CC2)c1 +COc1ccc(CCOC(=O)c2cccc(NC(C)=O)c2)cc1 +CC(=O)Nc1ccccc1CNc1ccc(N(C)C(C)=O)cc1 +CCOC1CCN(C(=O)c2sccc2-c2ccc(F)cc2)CC1 +Cc1cc(CN(C)C(=O)Cn2cnc3ccccc3c2=O)no1 +CCOc1c(OC)ccc2c1CCNC2c1ccncc1 +Cc1ccnc(OCC23COCC2CN(C(=O)c2ccnn2C)C3)n1 +CC1CCCC(NC(=O)NC(CO)c2ccccc2)C1C +O=C(NCc1cccc(O)c1)c1cc(F)ccc1Br +CCC(C)NC(=O)c1onc(S(=O)(=O)CC)c1N +CC(OCC1CC1)C(=O)Nc1cccc(N(C)C(C)C)c1 +Cc1cc(C(=O)NCC(=O)NCC2CCCC2)on1 +NC(=O)C(NCCc1ccccc1Cl)c1ccccc1 +COC(=O)c1ccc2[nH]c(COC3CN(C)CC3F)nc2c1 +Cc1nc(C(=O)N(C)Cc2ccccn2)nn1-c1ccccc1Cl +COc1cccc(C2CCCCN2C(=O)C2N=CC(C)=N2)c1 +Cc1nc(N2CCN(Cc3cnc(C(C)C)s3)CC2)sc1C +Cc1cc(C(O)C(=O)Nc2c(C)cccc2C)ccc1F +Cc1nc2nc(SC(C)C(=O)Nc3ccccc3)nn2c(C)c1C +CCC(=O)Nc1cccc(C(=O)Nc2cccc(C)c2)c1 +COCC(C)NS(=O)(=O)c1cc(C)ccc1C +CN(C(=O)c1cccc(-c2ccoc2)c1)c1cccnc1N1CCCC1 +Cc1ccc2[nH]nc(C(=O)OCc3ccc(-n4ccnc4)nc3)c2c1 +COCc1nnc(NC(=O)c2cc3cc(OC)ccc3o2)s1 +Cc1cc(NC(=O)COC(=O)CSc2ccc(C)c(C)c2)no1 +CN(Cc1ccccc1)C(=O)c1cc2sccc2[nH]1 +O=C(NCCc1coc(-c2ccccc2)n1)N1CCC(CO)CC1 +C#CCN(C(=O)Cc1cccc(OCC#N)c1)c1nccs1 +CCS(=O)(=O)N1CC2CCCC(OCc3cccnc3)C2C1 +OC1CCN(c2ncc(-c3ccc(Cl)cc3)cn2)CC1 +O=C(Cn1ccc2ccccc21)N1CCC(Oc2cccnn2)CC1 +Nc1nc(NC2CC2)c2ncn(C3C=CC(CO)C3)c2n1 +Cc1cccc(-n2ncc3c2CCCC3NC(=O)c2ccc[nH]2)c1C +Cc1cc(C)n(CC(C)CNC(=O)c2ccc(Cl)cc2F)n1 +CC1(C)C2CCC1(CS(=O)(=O)Nc1ccccc1Cl)C(=O)C2 +Cn1cc(Br)cc1C(=O)NCc1cscn1 +OCc1sc(COc2ccccc2Cl)nc1C1CC1 +Cc1csc(NC(=O)COc2ccc(Br)cc2F)n1 +Cc1nnc(SCCC(=O)Nc2cccc(Cl)c2)n(N)c1=O +COc1ccc(NC(=O)COC(=O)c2nccnc2N)cc1 +Cc1ccc(CNC(=O)CNC(=O)c2cc(F)cc(F)c2)c(C)c1 +COc1ccc(C(=O)N2CCc3sccc3C2)c(O)c1 +COCCOCC1NCCc2ccc(C)c(F)c21 +CS(=O)(=O)c1ccccc1NCC1COCCO1 +O=C1c2cccc(Br)c2CCC12CC2 +CCc1nc(CC(=O)Nc2ccc(C)cc2Cl)cs1 +Cc1ccc(CNC(=O)NC2C3CCOC3C2(C)C)c(N(C)C)c1 +COc1ccc2cnccc2c1N(C)CCc1ccncc1 +CC1N(CC2CC2)C(=O)COC12CCN(C(=O)c1ccnnc1)CC2 +N#Cc1cccc(-n2nnc(-c3cccnc3)c2N)c1 +c1ccc(-c2csc3ncnc(NCCCn4ccnc4)c23)cc1 +CC(=O)Nc1cc(C(=O)N(Cc2ccco2)C2CCCC2)ccc1F +CN(Cc1ccc(-n2cccn2)cc1)C(=O)CCC(F)(F)F +Cc1nc(COC(=O)c2cccnc2OCC(F)F)oc1C +Cc1nc(C)c(C(=O)NCc2ccc3c(c2)ncn3C)s1 +Cc1nnc(SCC(=O)c2cc3ccccc3oc2=O)o1 +CC(NC(=O)C1(C#N)CCCCC1)c1ccncc1 +N#Cc1ccc(CN2CCN(C3Cc4ccccc4C3O)CC2=O)cc1 +CN(Cc1ccc(Br)cc1)S(=O)(=O)c1cccs1 +CC(=O)Nc1ccc(F)c(C(=O)OCCC(C)C)c1 +COCc1noc(-c2ccc(-c3c(F)cccc3OC(C)C)nc2)n1 +O=C(Cc1ccc(N2CCNC2=O)cc1)NC1CCC2CCCC21 +CS(=O)(=O)N1CC(C(=O)NCc2ccccn2)C1 +CCN(CC(=O)OC)C(=O)c1cc(F)ccc1F +O=C(Nc1ccc(F)cc1)c1ncc(-c2ccncc2)o1 +CC(C)CNC(=O)C(C)NC(c1ccccc1)c1ccco1 +O=C(NC1(C(=O)NC2CC2)CCCCC1)c1ccc2cncn2c1 +CC(O)(CNC(=O)c1ccc(F)c(F)c1)c1ccsc1 +O=C(C1CCOC1)N1CCC(O)(c2cccc(C(F)(F)F)c2)CC1 +COc1ccc(C(=O)CSc2nnc(C)s2)cc1OC +CC(C)(C)n1nnnc1SCC(=O)c1cccc(C(F)(F)F)c1 +O=C(NCCCC(=O)N1CCc2cc(F)ccc2C1)c1ccccc1 +CCCCn1ncc(C)c1NC(=O)c1ccnc(OC)c1 +Cc1ccc(C(=O)N2CCCC3CCCC32)c(=O)[nH]1 +Cc1ccnc(SCc2cc(O)n(-c3ccc(F)cc3)n2)n1 +CC(C)S(=O)(=O)c1ccccc1NC(=O)NC(C)(CO)C1CC1 +CCOC(=O)Cn1c(=O)c2c(ncn2C)n(C)c1=O +NC(=O)c1cc(Cl)ccc1NC(=O)C1CC(=O)Nc2ccccc21 +COCCn1c(SC(C#N)C2CCCCC2)nc(C)c1C +CN(Cc1ccco1)C(=O)c1cccc2cn[nH]c12 +CC(CN1CCCC1=O)NC(=O)c1ccc(Br)cc1F +O=C(CCc1nc(-c2cccs2)no1)NCCc1ccccc1 +Cc1cc(C)n2c(CNS(=O)(=O)c3ccc(F)cc3)nnc2n1 +C=CCN(C(C)=O)c1nc(C)c(Br)c(OC)n1 +Cc1noc(C)c1CCC(=O)N(C)C(C)c1ccccc1Cl +CC1CCCCN1C(=O)Cn1ncn2c(cc3ccsc32)c1=O +CCC(NC(=O)c1ccccn1)c1ccc(C)cc1 +O=C(Nc1ccccc1-n1cnnn1)C1CC2CCC1O2 +CCn1c(CC2CCN(C(=O)c3cc(C)n[nH]3)CC2)n[nH]c1=O +COCCNc1ccc(CNC(=O)Nc2ccccn2)cc1 +Cc1cc(C(=O)COc2ccc(-c3nnco3)cc2)c(C)n1C1CC1 +CCOC(=O)C1CCN(S(=O)(=O)c2cn(C)c(C)n2)CC1 +CC(=O)N(C)Cc1cccc(NCc2c[nH]nc2C(C)(C)C)c1 +N#Cc1ncc(Br)c2ccc(F)cc12 +CN(C(=O)COC(=O)c1c[nH]c2ccccc12)C1(C#N)CCCCC1 +CN(CC(O)C1CC1)C(=O)C1CC1c1ccccc1F +CNS(=O)(=O)c1cnn(C2CCC(C)CC2)c1N +CC(=O)c1nc(-c2cn(C)c3ccccc23)cs1 +Cc1noc(-c2cccn2Cc2cccc(F)c2)n1 +COC(=O)C(CC(C)C)NC(=O)c1ccc(C#N)cc1 +O=c1c(Oc2cnn(-c3ccccc3)c2)coc2cc(O)ccc12 +O=C(NC(Cc1ccccc1)C(O)c1nccs1)c1cscn1 +Cc1nn(Cc2ccc(F)c(F)c2F)c2c1C(=O)CCC2 +COc1ccccc1C1CCN(S(=O)(=O)c2ccccc2)C1 +N#CC1(C(=O)N2CCC(Nc3cccnc3)CC2)CCCC1 +CCS(=O)(=O)NCC(C)(C)c1ccc(Br)cc1 +COCCNC(=O)Cn1cc(C(=O)c2ccccc2)c2ccccc21 +CC(=O)Nc1ccc(CC(=O)NC2(c3noc(C)n3)CCCC2)cc1 +CCCNC(=O)CC1CCN(C(=O)Nc2ccccc2)CC1 +O=C(CC1CCCC1)N1CC2CCN(c3ncccn3)CC2C1 +CN(C)C(=O)c1cnn(-c2ccccc2)c1C(F)(F)F +CCCCNC(=O)c1cn(CC)cc2c(=O)n(-c3ccccc3)nc1-2 +COc1ccc(C2C(C(=O)N3CCCC3)CCC(=O)N2C)cc1 +Cc1ccccc1C1CC1C(=O)N1CCCC(N2CCCC2=O)C1 +CCCOCC1CCN(C(=O)c2c[nH]nc2-c2cccc(F)c2)C1 +O=C(Cc1c(Cl)cccc1Cl)NCCc1nnc2n1CCC2 +CC(=O)NCC(=O)N(C)C(C)c1ccccc1Cl +CNC(=O)c1ccc(NC(=O)c2csnc2C)cc1 +CNC(=O)c1cccc(CNc2cc(C)nc(-c3ccncc3)n2)c1 +O=C(NCCCn1cncn1)N1CCN(c2ccccc2)CC1 +CC(OC(=O)c1cccnc1)C(=O)Nc1cccc(Cl)c1 +COc1ccccc1C(=O)N1CCC(c2nnc(C3CC3)o2)CC1 +C=C(C)CN(CC)C(=O)c1cc(S(N)(=O)=O)ccc1OC +COc1ccc(N2CC(C(=O)Nc3nnc(C)s3)CC2=O)cc1 +N#Cc1ccc(OCC(=O)Oc2ccc(Cl)cc2)cc1 +CCCNC(=O)Cn1nc(C)c2c(C(F)(F)F)cc(C3CC3)nc21 +CC(C)NC(=O)CNC(=O)C12CC3CC(CC(C3)C1)C2 +N#Cc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1 +COc1ccc(Cl)cc1NCCOc1cccc(N)c1 +COc1ccc(O)c(C(=O)NCc2ccc(C)s2)c1 +O=C(Cn1nc2nc(N3CCCC3)ccn2c1=O)Nc1ccccc1 +O=C(c1ccccn1)N1CCC2(CC1)CC(Oc1cccnc1)CO2 +c1ccc(OCCSc2nncn2-c2ccccc2)cc1 +CCc1nc(COc2ccc(-c3nc(C(C)(C)OC)no3)cc2)no1 +Cc1ccc(-c2nnc(C(NC(=O)C(C)(C)C)C(N)=O)o2)cc1 +Cc1nc(CNC(=O)C2CCC(C(N)=O)CC2)c(C)s1 +CCn1cc(C2CC(C(F)(F)F)n3nccc3N2)cn1 +CCc1nn(CCC(=O)Nc2ccc(F)cc2)c(=O)c(C#N)c1CC +Cc1cc(C)cc(C(=O)Nc2cccc(N)c2C)c1 +CCCCn1ncc(-c2ccc(F)c(C)c2)c(CO)c1=O +CC(C)(C)NC(=O)CNCc1ccc(C(F)(F)F)cc1 +COCCn1c(N)c(NCCC(N)=O)c(=O)[nH]c1=O +CCCN1CCN(C2CCN(C(=O)c3ccccc3F)CC2)C1=O +Cc1cccc2c(=O)n(CC(=O)NCCc3cccc(F)c3)cnc12 +CN1CC(Nc2nc(-c3ccncc3)nc3c2CCC3)CCC1=O +COC(C)(C)c1noc(-c2ccc(-c3ccccc3)n2C)n1 +Cn1cc(-c2csc(N3CCN(C(=O)OC(C)(C)C)CC3)n2)cn1 +CN(C(=O)COC(=O)c1ccc(C#N)cc1)c1ccccc1 +CC(=O)Nc1cc(NS(=O)(=O)c2cn[nH]c2)ccc1C +N#Cc1c(-c2cccs2)nc2sc(-c3cccnc3)nn12 +CS(=O)(=O)c1ccccc1C(=O)Nc1ccc(F)c(Cl)c1 +Cc1cc2c(=O)n(CCCCC(F)(F)F)cnc2s1 +C=CCNC(=O)NC(c1ccc(OC)cc1)C(F)(F)F +O=c1[nH]c(CN2CCSc3ccccc32)nc2ccccc12 +CC(NC(=O)c1ccccn1)C(=O)N1CCCCC1 +CCOc1ccccc1NC(=O)c1cnc2ccc(C)cn12 +CC1CC(=O)c2cc(C(=O)Nc3cccc4cccnc34)c(=O)[nH]c2C1 +Cc1cc(=O)oc2c(C)c(OCC(=O)OC(C)C)ccc12 +O=C(Nc1cccnc1)C1CCCN(C(=O)NCc2cccs2)C1 +O=C(C(O)Cc1cccc(Cl)c1)N1CCNCC1 +CCn1nc(C)cc1C(=O)OCC1CCN(CC(F)(F)F)CC1 +CCOc1ccccc1NC(=O)Nc1cnn(CC2CCCO2)c1 +O=C(Cc1cc(Cl)cc2c1OCOC2)N1CCOCC1 +COc1ccnc(NC(=O)c2cccnc2OCC(F)F)c1 +COc1cc(NC(=O)C(C)Sc2nc(C)cs2)cc(OC)c1 +COc1ccc(OC)c(NC(=O)CCc2c(C)n[nH]c2C)c1 +Cc1ccc(NS(=O)(=O)c2ccc(C(=O)NCCCO)cc2)cc1 +Cc1nnc(NC(=O)CCCn2sc3ccccc3c2=O)s1 +Cc1cccc(NC(=O)CCNC(=O)c2c[nH]c3cccc(F)c23)n1 +COCc1nc(Cc2ccccc2OC)sc1C(C)=O +Cc1ccc(C(=O)NC(C)Cc2ccc(Cl)cc2Cl)cn1 +CCn1nc(C)c(Cl)c1C(=O)Nc1cccc(C)n1 +COc1cc(C)ccc1NC(=O)CN(C)C(=O)c1ccccc1 +CCOC(=O)N1CCN(c2nc3ccsc3c(=O)s2)CC1 +O=C(Nc1ccc2c(c1)COC2)c1csc(-c2ccco2)n1 +CC(NC(=O)c1ccc[nH]c1=O)c1ccc(NC(=O)NC2CC2)cc1 +CCCN(CC(=O)N(C)C)C(=O)Cc1ccc[nH]1 +COc1cc(NC(=O)N2CCCCCC2)ccc1N1CCOC1=O +Cc1ccc(C(=O)CCC(=O)N2CCC(=O)CC2)cc1 +O=C(Cn1cnc2c(cnn2CCO)c1=O)Nc1cccc(F)c1 +CN(C)c1cccc(C(=O)Nn2cnc3ccccc3c2=O)c1 +Cc1c(C(=O)NC(C)C(=O)NC(C)(C)C)cnn1-c1ccncc1 +CN1C2(CCN(Cc3ccccc3)C2)c2ccccc2S1(=O)=O +Oc1cccc(-c2nnc(-c3cccc(O)c3)nn2)c1 +COC(=O)NC1CC2C(=O)NC(C(C)O)C(=O)N2C1 +CC(=O)c1sc2nc3c(c(-c4cccs4)c2c1N)CN(C)CC3 +Cc1ccc(C(=O)NCc2ccc3c(c2)OCO3)s1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(Br)cc1 +COCCNc1nc(-c2ccccc2O)nc2ccccc12 +Cc1nc(C)c(C(=O)NC(C)c2ccccc2)s1 +Cc1cc(N)c(S(=O)(=O)NCC2CCCC2)cc1C +CC(c1ccncc1)N(C)C(=O)CCCNC(=O)NC1CCCCC1 +O=C(NCCCn1cccn1)c1cc2cn(C3CCCC3)cc2s1 +CCc1ccc(C(=O)NC(C#N)c2cc(OC)c(OC)c(OC)c2)o1 +O=C(Cn1c(=O)cnc2ccccc21)Nc1ccc(F)c(Cl)c1 +COc1ccc(-c2nn3c(-c4cnn(C)c4)nnc3s2)cc1 +NC(=O)c1cccc(NCC(=O)NC2CCCCC2)c1 +Cc1csc(=O)n1CCC(=O)N1CCCC(C(F)(F)F)C1 +CCOC(=O)C(C)NS(=O)(=O)N1CCC(C)CC1 +Cc1nc2cc(F)ccc2cc1C(=O)OCC(=O)c1ccccc1 +CCN(CCc1nccs1)Cc1nc(C)c(C)o1 +Cc1nn(C)c(C)c1CC(=O)NCc1nc(-c2cccs2)no1 +CC(C)c1ccc2[nH]c(=O)c(CNc3ccc4[nH]ncc4c3)cc2c1 +COc1ccc(CCCNC(=O)c2ccnc(-n3cncn3)c2)cc1 +CCN1CCN(Cc2nc(C)cc(-c3ccccc3)n2)C(=O)C1=O +COc1ccc(F)cc1NC(=O)c1cc(C2CC2)n(C(C)(C)C)n1 +Nc1nc(N)nc(-c2cccc(-c3nc(N)nc(N)n3)c2)n1 +COc1ccc(C(NC(=O)Cn2ccc(=O)[nH]c2=O)C2CC2)cc1 +Cc1occc1C(=O)N1CCC2(CC1)CN(c1ncccn1)CCO2 +CC(=O)Nc1ccc(NCc2cnc(C)s2)cc1 +O=C(Cc1ccc(S(=O)(=O)N2CCCCC2)cc1)NCC1CC1 +Cc1noc(C2CC3OCCC3N(C(=O)c3cc(C)[nH]c3C)C2)n1 +CC(C)CNC(=O)NCc1ncc(-c2ccccc2)o1 +COc1ccccc1CNC(=O)c1cn(-c2ccccc2Cl)nn1 +COc1ccccc1OCc1nnc(-c2ccccc2)o1 +CCCC1CN(C(=O)C(CC)N2CCCC2=O)CCO1 +COc1cc(C)c(C)cc1C(=O)CNC(=O)C(C)C +CCCNC(=O)Cn1cc(Br)ccc1=O +COc1ccc(C(=O)NCC(OC)c2cccc(OC)c2)cc1 +Cc1cc(F)cc(NC(=O)NCc2nc(C)sc2C)c1 +Cc1nnc(NC(=O)COc2cccc3c2OC(C)(C)C3)s1 +O=C(c1cc(NCCCOc2cccnc2)ccn1)N1CCOCC1 +COc1cccc(C(=O)Nc2ccc(N3CCOCC3)cn2)c1 +CCNC(=O)NC1(C(=O)N(C)CCCOC)CCCC1 +CN(C)S(=O)(=O)Nc1ccc(Oc2cccnc2)nc1 +CC(C)C(CO)NC(=O)c1scnc1C1CC1 +CN(Cc1nc2ccccc2s1)C(=O)c1ccc(F)cc1F +COc1ccc(C(=O)C(C)Oc2ccccc2C#N)cc1 +CCc1nn2c(CO)c(-c3ccc(C)cc3C)nc2s1 +CCCn1c(C2CCN(C(=O)NC3CCCC3)C2)nc2cccnc21 +CC(C)c1ncc(CN2CCc3cccc(F)c3C2)s1 +CN1CC(=O)N(c2cnn(C)c2)CC12CCN(C(=O)c1ccoc1)C2 +COCCC(C)C(=O)N1CCC(Oc2cccc(Cl)c2)C1 +O=C(Nc1cccc2cn[nH]c12)c1ccc(-n2ccnn2)cc1 +O=C(NCc1ccco1)c1c(F)cc(Br)cc1F +CC(=O)Nc1cccc(CNC(=O)Nc2cn[nH]c2)c1 +Cn1nnc2c1CCN(c1ncccn1)C2COCC1CC1 +CC(C)NC(=O)c1ccc2nc(N3CCOCC3)sc2c1 +O=C(Nc1ccncc1)C1CNc2ccccc2O1 +CN(Cc1ccc2c(c1)OCCO2)c1ccc(C(F)(F)F)cn1 +FC(F)(F)Oc1ccc2c(c1)C(c1ccco1)NCC2 +COc1ccc(O)c(C(=O)NCc2cn(-c3ccccc3)nn2)c1 +N#Cc1ccc(S(=O)(=O)Nc2ccccc2O)cc1 +CCOc1ccc(NC(=O)C2CC2)cc1S(N)(=O)=O +CCc1ccc(NC(=O)CS(=O)(=O)c2ccc(F)cc2)cc1 +CC1(O)CCN(C(=O)CCCOc2ccccc2)CC1 +CC(=O)NC1(CC(=O)c2ccccc2)C(=O)N(C)c2ccccc21 +CC(=O)N(C)CC(=O)NCCCc1cn[nH]c1C +O=C(CCNC(=O)c1n[nH]c2ccccc12)NCC1CC=CCC1 +CCC(C)Nc1nnc(-c2ccc(=O)n(CC)n2)s1 +C=CCN(Cc1cccc(C#N)c1)S(=O)(=O)c1ccc(C#N)cc1 +O=C1C(n2cc(-c3ccccc3)sc2=O)CCN1CC(F)(F)F +CCC(C)(C#N)NC(=O)c1cc2cc(C)ccc2o1 +CCC(CO)NC(=O)NC(c1ccc(F)cc1)c1nccn1C +Cc1ccc(N)c(C)c1NC(=O)c1ccc(Br)cc1F +Cn1c(=O)n(-c2ccccc2)c(=O)c2c3c(sc21)CCCC3 +Cc1nn(C)c(C)c1C(=O)NCCNc1cnccn1 +Cc1nnc2ccc(-c3noc(COc4ccc(Cl)cc4)n3)cn12 +Cc1cnc(C(=O)NC2CC3(CCOCC3)Oc3ccccc32)cn1 +COc1ccc2ncc(NC(=O)N3CCC(O)CC3)c(O)c2n1 +CCc1cc(CC)c(NC(=O)N2CCC(=O)NCC2C)c(CC)c1 +O=C(Nc1nc(-c2ccccc2)cs1)c1cn2cccnc2n1 +Fc1ccc2nc(CCCn3ccnc3-c3ccncc3)[nH]c2c1 +CCOCC1CN(C(=O)c2ccsc2)Cc2cn(CC3CC3)nc21 +O=C(Nc1nccs1)c1ccc(COc2ccc3c(c2)OCO3)o1 +CCCC1CN(C(=O)c2cnn(-c3ccccc3)c2CC)CCO1 +Cn1c2c(c(=O)n(C)c1=O)C(c1cccs1)CC(=O)N2 +O=C(COC(=O)c1ccc(O)cc1O)c1ccc2c(c1)OCCO2 +Cc1cccc2[nH]c(C3CCCN(c4nnc(C5CCC5)o4)C3)nc12 +O=C(Nc1cnc(-n2ccnc2)nc1)Nc1ccc2c(c1)OCCO2 +O=C1CCC2C(CCN2C(=O)c2cccs2)N1Cc1cccnc1 +CC(C)N(Cc1cccnc1)C(=O)NCCc1ccc(F)cc1 +CC(=O)NCc1cc(Br)cc2c1OCOC2 +CC(=O)C(C)N1CC(C(C)C)Oc2cccc(N)c21 +COc1ccc(CCCNC(=O)NCc2cnn(C)c2)cc1 +COc1cccc(C(=O)C(C#N)c2nc(C)cs2)c1 +Cc1ccc2c(c1C)CCNC2c1cnccc1Cl +Cc1c(C(=O)NC(C)c2ccccc2)nnn1-c1ccc(Cl)cc1 +CCCn1ncnc1-c1ccccc1C(=O)N(C(C)C)C(C)C +CCCNC(=O)c1cccc(CNC(=O)c2cc(C(N)=O)cs2)c1 +N#Cc1cc2n(n1)CCN(C(=O)c1cnc(Nc3ccccc3)nc1)C2 +COCCCN(C)C(=O)Nc1ccc(S(C)(=O)=O)nc1 +O=C(Cc1cccc(F)c1F)N1CCc2ccccc2C1 +O=C(Nc1cccc(C(=O)C2CC2)c1)c1ccc(F)cc1 +CCCCN(CC)C(=O)CS(=O)(=O)c1ccccc1Cl +COc1ccc(F)cc1NC(=O)NCC(C)c1ccsc1 +CCOc1ccccc1NC(=O)Nc1nnc(-c2ccn(C)n2)o1 +COCCC(NC(=O)NCc1ncn(C)n1)c1ccc(Cl)cc1 +Cc1c(C(=O)Nc2ccnn2CC(C)C)cnn1-c1ccccc1F +Cc1nc(CNC(=O)c2cccc(Br)c2)no1 +COc1cccc(COC(=O)c2cc(C)oc2C)c1 +CNC(=O)Cn1cc(NC2CCCCC2OC)cn1 +Cc1ccnc2nc(C(=O)NCc3nc4ccccc4[nH]3)nn12 +CCCNC(=O)CNc1ccccc1Br +Cn1nc(C(=O)Nc2cccc(Cl)c2)cc1NC(=O)c1ccco1 +N#Cc1sc2nc3c(cc2c1N)CN(Cc1ccccc1)CC3 +COc1cc2c(=O)[nH]c(CCC(C)C)nc2cc1OC(F)F +CCOC(=O)c1cnc(Nc2ccccc2)nc1C +CCn1nc2ccc(S(=O)(=O)N3CCOCC3)cn2c1=O +O=C(Nc1ccc(F)cc1)N1CCCC1c1nnc2n1CCCCC2 +Cc1cc(-c2nnc(NC(=O)C3CCCCC3)o2)nn1C +CCC(C)NC(=O)C(C)Oc1cccc(C)c1N +O=C(CC1COc2ccccc2O1)N1CCOCC1 +CN(C)C(=O)C1CCCN(c2ncnc3sccc23)C1 +C=CCn1ccnc1-c1cncc(Br)c1 +Cc1c(C)c(C(=O)N2CCOCC2)n(Cc2ccccc2F)c1C +Cc1ccc(-n2cnnc2SCCn2cccn2)cc1Cl +CNC(=O)c1cccc(NC(=O)COc2cc(C)ccc2C(N)=O)c1 +COCCCN(C)C(=O)Nc1ccc(-c2nnnn2C2CC2)cc1 +Cc1cc2nc(-c3ccccc3)cc(NCCC(N)=O)n2n1 +O=C(NCC(F)(F)F)c1ccc(Oc2ncccn2)cc1 +CC(C)c1cc(C(=O)Nc2ccc(-n3cncn3)c(Cl)c2)no1 +Cc1ccc(OCC(C)NC(=O)NCC2CCC2)cc1 +Fc1ccc2nc(C3CC3)n(CC(F)(F)F)c2c1F +CC(C)C1CN(c2ncccn2)CCC(=O)N1CC1CC1 +O=C(Cn1c(C2CC2)nc2ccccc21)N1CCCCC1 +CN(CCN1CCOCC1)C(=O)CCOc1ccccc1Cl +CC(C)C1CN(CC(F)(F)F)CCN1CC(=O)N(C)CCC#N +COc1nccnc1-c1cccc(-c2cc[nH]n2)c1 +CN(CCO)C(=O)c1ccc(OCc2noc3c2CCCC3)cc1 +Cc1nnc(CNC(=O)C2CCN(C(=O)Nc3cccs3)CC2)o1 +CCOC(=O)C1CC(=O)N(c2ccc(Br)cc2OC)C1 +COc1ccc(NC(C)=O)c(NCc2nc(CC(C)C)no2)c1 +Nc1ccc2nc(NC(=O)C3CCCC3)sc2c1 +CN(C)C(=O)c1ccccc1NCC(=O)NCc1cccc(Cl)c1 +O=C(COC1CCCC1)Nc1cccc(Oc2ccncc2)c1 +CC(C)c1noc(C(C)Sc2nc3ccccc3[nH]2)n1 +CCOCCOc1ccc(Cl)cc1NC(=O)C1CC(=O)N(C)C1 +NC(=O)c1snc(-c2ccc(Cl)cc2Cl)c1N +Nc1c(C(=O)NCc2ccccc2Cl)nnn1Cc1ccccc1 +CCNC(=O)NCC(OCCO)c1ccc(C)cc1 +CC(c1ccco1)N(C(=O)NC1CC(=O)N(C(C)(C)C)C1)C1CC1 +COc1ccccc1C(CNC(=O)NC(C)(C)C)OC +COc1cc(C(=O)Nc2cc(Cl)ccc2Cl)on1 +CC(C)c1nc(C(=O)N2CCC3(CC2)OCCCC3O)cs1 +O=C(CCNc1ncccn1)N1CCN(CCc2ccncc2)CC1 +CCOc1ccc(NC(=O)CNC(=O)c2ccc(F)c(F)c2)cc1C +CS(=O)(=O)N1CCC2(CC(=O)N(c3cccnc3)C2)C1 +CCn1ccc(C(=O)NCC2(c3ccc(C)cc3)CCOCC2)n1 +CC(=O)NC(CC(=O)N1CCCCC1)c1ccc(C)cc1 +CC(NS(C)(=O)=O)C(=O)N(C)Cc1cnn(-c2ccccc2)c1 +CC(C)Cn1cc(C(=O)NC2CCCC2)c(=O)c2c(N)cccc21 +CCC1CN(C(=O)C2c3ccccc3Oc3ccccc32)CCO1 +O=C(Cc1nnc(-c2ccccc2)o1)NCc1ccc(F)cc1 +COC(=O)c1cccc(CSc2nnc(C3CC3)n2C)c1 +COc1ccc(C(NC(=O)Cc2ccc[nH]2)c2nccn2C)cc1 +CSc1cccc(NC(=O)C(C)Sc2ccc(O)cc2)c1 +COc1ccc(-c2nc(CCNC(=O)Cn3cccn3)co2)cc1 +Cc1nc2ccccc2n1CC(=O)NCc1ccc(Cl)cc1 +COc1ccc(C2CC(=O)c3c(OC)cc(OC)cc3O2)cc1 +O=C(CN1CCN(CCO)CC1)NC1CCCC(C(F)(F)F)C1 +CCc1nc2ccccc2n1C(=O)Nc1ccccc1 +CC(=O)N1CCC(NC(=O)Nc2cccc3cnccc23)CC1 +CC(=O)NCc1ccc(-c2csc(COc3ccccc3)n2)cc1 +Nc1cc(F)ccc1C(N)C(=O)NCc1ncc[nH]1 +CCCCN(C)C(=O)C1CCN(c2ncnc3onc(C)c23)CC1 +O=S(=O)(NC1CCCCC1)c1ccc2c(c1)CCN2 +CSc1nc2nnc(C(=O)Nc3ccc(C)cc3)c(C)n2n1 +Cc1ccn2c(=O)c(NC(=O)c3ccc(Cl)cc3)c(C)nc2c1 +CCN(C(=O)Cc1ccc(F)cc1F)c1nc(C)cs1 +COc1cccc(C(=O)Nc2ccn(-c3ccccc3)n2)c1F +CS(=O)(=O)N1CCCN(C(=O)c2cc3ccccc3c(=O)[nH]2)CC1 +COCCCN1C(=O)c2ccccc2NC1(C)CC(C)C +COCCCN(C)C(=O)NCc1cc(F)cc(Br)c1 +CC(=O)c1cc(-c2ccc3c(c2)OCCO3)nn(C)c1=O +O=C(NCCc1ccccc1)C(C(F)(F)F)C(F)(F)F +C=C(C)COc1cccc(C(=O)N2CCC3(CCOCC3)CC2)c1 +CCS(=O)(=O)c1ccc(C(=O)NCC2CCC2)cc1 +COCCn1cc(NS(=O)(=O)c2c(C)cc(C)cc2C)cn1 +CCCCc1nnc(NC(=O)NC2CCCC2C(=O)OC)s1 +Cc1cccc(OCC(=O)Nc2nnc(Cc3ccc(F)cc3)o2)c1 +COCC(=O)N1CCC2(CC1)CC(CC(=O)N(C)C)c1ccccc12 +COC(=O)C=c1sc2n(c1=O)C(C)c1ccccc1N=2 +N#Cc1ccc(NCC(=O)c2ccc3c(c2)OCCO3)cc1 +O=C(NCc1ncc[nH]1)C1COc2ccc(Br)cc21 +CC(C)(CNS(=O)(=O)c1cccc2c1COC2=O)c1ccncc1 +CCc1ccc(S(=O)(=O)N(CC)CC(=O)OC)cc1 +COC(C)C(=O)NCCC(=O)NCc1cccnc1 +CCNC(=O)N1CCC(Oc2nncc3ccccc23)CC1 +CC(C)Cc1nnc(NC(=O)N(C)C(C)c2cccc(O)c2)s1 +Cc1nc(-c2cccc(NC(=O)C(C)Sc3ccccc3)c2)n[nH]1 +CC(=O)c1cccc(NC(=O)NC2CC(=O)N(c3ccccc3)C2)c1 +Cc1cc(-c2c(-c3ccccc3)ncn2CCc2ccc(O)cc2)[nH]n1 +CNC(=O)c1cnc(C=Cc2cc(OC)c3c(c2)OCCO3)s1 +COCc1cc(C(=O)Nc2nnc(C3CC3)s2)ccc1F +CCn1ccc(C(=O)N2CCC(Oc3ccccc3OC)CC2)n1 +Cc1cnccc1-c1cnn(CCNC(=O)C2CCCC2)c1C1CC1 +Cc1nc(C(C)(C)NC(=O)CCc2ccco2)sc1C +C=CCNC(=O)C12CC3CC(CC(NC(C)=O)(C3)C1)C2 +Cc1c(C#N)c2ccccc2n1CC(=O)N1CCCCCC1 +CC(O)CN(CC(C)O)C(=O)c1ccc(F)c(F)c1 +Cc1cc(C)c(CNC(=O)NCC(O)c2ccccc2)c(=O)[nH]1 +CN(Cc1cccc(C#N)c1)C(=O)Nc1nc2ccccc2s1 +Cc1cccc(NC(=O)CSc2nnnn2C2CCCC2)c1 +Cc1ccc2c(c1)nc(C(=O)c1ccncc1)n2C +CCCn1c(=O)n(CCC(=O)Oc2ccc(C#N)cc2)c2ccccc21 +CCOc1ccccc1CNC(=O)c1ccccc1F +COc1ccccc1OCC(=O)NC(C(C)C)C(C)C +CCCOC(=O)Cn1nc(CO)cc1-c1ccccc1 +CC(C)CC(=O)Nc1ccccc1N1CCOCC1 +CC(C(=O)NCC1COc2ccccc2O1)N1CCOC(C)(C)C1 +Cc1nc(C)c(C(=O)Oc2cccc(C(=O)NC3CC3)c2)s1 +COCC(=O)NC1CCCc2c1cnn2C(C)(C)C +COC(=O)C(NC(=O)c1cnn(-c2cccc(Cl)c2)c1)C(C)C +CCC1CN(CC(=O)N2CCCC2)c2ccccc2S1 +O=C(NCc1ccc(F)cc1)c1ccc(N2CCOCC2)cc1 +Cc1c(Cl)cccc1NC(=O)CN1CCCCCC1=O +COc1cccc(NC(=O)Cn2nc(-c3ccc(C)cc3)ccc2=O)c1 +CCNC(=O)CCN1CCN(C(=O)C2CCCO2)CC1 +O=C(NC1CCC1)NC1CCN(CC(F)(F)F)C1=O +O=C(NCCN1CCCCCC1=O)c1ccccc1-n1cnnn1 +O=C(CSc1cccs1)Nc1nnc(-c2ccco2)o1 +CCCNc1ncnc(Oc2cccc3cccnc23)c1N +CCCN(C)C(=O)c1cnn(-c2ccncc2)c1C +CCn1cnnc1CNC(=O)NC1CCc2c(Cl)cccc21 +Cn1ncc(N2CCC(Cc3ccccc3)C2)c(Br)c1=O +CS(=O)(=O)c1ccccc1NC(=O)Cn1nc2ccccn2c1=O +N#CCCN(Cc1ccco1)S(=O)(=O)CC1CCCCC1 +Cc1cc(C)c(C(=O)Nc2ccc(C)nc2)c(C)c1 +N#Cc1cccc(Cn2cnc3c(oc4ccccc43)c2=O)c1 +O=C(Nc1c(F)cccc1F)N1CCN(C(=O)c2ccco2)CC1 +CC(C)CN1CCN(Cc2noc(C(C)(C)C)n2)C(C)C1=O +CCCC(C)N(C)C(=O)c1c[nH]c(=O)c(Cl)c1 +CCn1c(NCC2CCCO2)nc2c(C)nn(C)c2c1=O +Cc1noc(C)c1CC(=O)N(Cc1ccccc1)C(C)C +Cc1ccccc1CC1CN(C(=O)Cc2ccc(O)cc2)C1 +Cc1ccccc1CNc1cc(-c2ccncc2)nc2ccnn12 +Cc1ccc(-n2nc(C(=O)NCCS(N)(=O)=O)c3c2CCC3)cc1 +Cc1ccc(NC(=O)c2cccnc2N2CCCC2)c(Cl)c1 +Cc1nc(-c2ccncc2)nc2c1CC(=O)N2CC1COCCO1 +CCCC(=O)NCc1cc(OC)c(OC)cc1Br +Cc1cc2nc(COC(=O)C(C)(C)C)cc(=O)n2o1 +Cc1c(NC(=O)c2cn(C)nc2C(C)(C)C)cnn1-c1ccccc1 +CCc1ccc(S(=O)(=O)Nc2cccc(C(N)=O)c2C)cc1 +Cc1ccc2c(c1)C(NC(=O)N(C)Cc1nccs1)CCS2 +CC(C)CCNC(=O)C1CCCN(C(=O)Nc2cccs2)C1 +O=C(Cc1csc(-c2ncccn2)n1)Nc1ccc2c(c1)CCC2 +CCc1nnc(CNc2cc(Cl)cc3c2OCC3)o1 +O=C(NC1CCSc2ccccc21)C1CCCN(C(=O)C2CC2)C1 +C(=Cc1nnnn1-c1ccccc1)Nc1ccccc1 +CCOc1ccc(COC(=O)c2cccc(C#N)c2)cc1OC +CC(C)c1nc(CC(=O)Oc2cccc(NC(=O)C3CC3)c2)cs1 +C=CCN1CCN(C)C(=O)C12CCN(Cc1cnn(C)c1)C2 +CC1Cc2ccccc2N1S(=O)(=O)c1cccs1 +COc1ccc2nc(Cc3ccc(O)cc3)[nH]c(=O)c2c1 +O=C(C1CC(=O)N(C2CCOCC2)C1)N1CCOCC1 +CNc1nc(CNC(=O)Nc2cnc(C(C)(C)C)nc2)cs1 +Cc1cc(C)n2c(CN(C)C(C)Cc3ccsc3)cnc2n1 +CC(Sc1ncnc2ccccc12)c1nnnn1-c1ccccc1 +CCc1nc(C2CCCN2C(=O)c2cc(C)n(CC3CC3)c2C)no1 +CC(C)NS(=O)(=O)Cc1ccc(CNC(=O)C2CCC2)cc1 +Cc1nc(-c2ccc(Oc3nnc(C)c(C)c3C#N)cc2)no1 +CC(=O)c1c(C)[nH]c(C(=O)N(C)Cc2ccco2)c1C +CC(C)COc1ccc(-c2nc3scc(N)n3n2)cc1 +COc1ccc(CNC(=O)NCC2CCN(c3ccccc3)C2)cc1 +CCc1cccc(CC)c1NC(=O)c1cc(C)no1 +CCCc1nc(C(=O)NCc2nc(C)cc(C(F)(F)F)n2)cs1 +CC(=O)N1CCN(c2cnccn2)CC(CO)C1 +CNc1ccccc1C(=O)OCC(=O)NC1CCCc2ccccc21 +CCCCS(=O)(=O)NCC(=O)N1CCCCCC1c1ccco1 +Cc1c(C(=O)NC2CCN(C(C)C)C2=O)cnn1-c1ccncc1 +Cc1cc(C(O)C(=O)Nc2ccccc2Cl)ccc1F +c1ccc(-c2onc3ccc(C4OCCO4)cc23)cc1 +CC1CCC(NC(=O)C(C)Nc2ccc3c(c2)CC(=O)N3)CC1 +Cc1cc(C(=O)Nc2cnc3c(cnn3C(C)C)c2)c(C)o1 +Cn1cccc1C(=O)Nc1ccccc1N1CCCC1=O +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)N(C)Cc1cccc(O)c1 +CC(=O)c1csc(NC(=O)COc2ccc(C(F)(F)F)cc2)n1 +Cc1nnc(N2CCN(C(=O)c3ccccc3F)CC2)c(C#N)c1C +CCCN(C(=O)Nc1nccn(C)c1=O)C1CC1 +Cc1cc(C2CCCN2C(=O)C2CNC(=O)N2)no1 +O=C(c1cccc(F)c1)N1CCN(Cc2cnc3ccccn23)CC1 +Cn1c(C(=O)NC(C)(C)C)cc2ccc(Cl)cc21 +CSc1sc(NC(=O)c2ccc(N(C)C)cc2)nc1C +Cc1ccc(CNC(=O)NCc2ccc3c(c2)OCCCO3)cc1 +NC(=O)c1cccc(OCc2ncc(-c3ccccc3)o2)c1 +CN(CCOc1ccccc1)C(=O)Nc1cnn(C)c1 +O=C(CCn1ccc2ccc(F)cc21)NCc1cccnc1 +COc1cc(CNc2c[nH]ccc2=O)ccc1Cl +Cc1nn(C)cc1C(=O)Nc1ccc(Cl)c(Cl)c1 +CC(C)Cn1nccc1NC(=O)C(C#N)c1nc2ccccc2n1C +Nc1cc(Cl)ccc1SCC(=O)NCC1CCCO1 +CCOC(=O)CC1C(=O)NCCN1Cc1ccc(OC)cc1F +Cc1cc(C(=O)Nc2ccc(C(C)C)cc2)c2c(=O)[nH]n(C)c2n1 +CCc1noc(CC)c1CNC(C(N)=O)c1ccc(C#N)cc1 +Cc1cccc(C(=O)N(Cc2ccsc2)C2CC2)c1 +CC(=O)Nc1ccc(C)c(S(=O)(=O)N2CCC(C)CC2)c1 +Cc1nc2scc(-c3ccc4[nH]c(=O)oc4c3)n2c1N +CC(C)c1cc(OCC(=O)Nc2nccs2)nc(C(C)C)n1 +CCC(CCO)NC(=O)Nc1ccc(NC(=O)C(C)C)cc1 +CCCn1c(=O)n(CC)c(=O)c2c1nc(NC)n2C +CNC(=O)CCc1nc(-c2cc(OC)c(OC)c(OC)c2)no1 +COC(=O)Cn1c(=O)oc2cc(S(=O)(=O)NC(C)(C)C)ccc21 +NC(=O)NC(Cc1ccccc1)C(=O)Nc1cccc(F)c1 +O=C(NCc1cncc2c1CCN(Cc1ccoc1)C2)C1CC1 +Cc1cc(Cl)c(C(=O)NC(C)C(=O)N2CCOCC2)cc1C +Cc1cc(C)c(C(=O)NC2CN(C(=O)OC(C)(C)C)C2)c(C)c1 +COCC(C)NC(=O)NCCOc1cc(C)cc(C)c1 +CC(C)CCNC(=O)CCc1cn2cccnc2n1 +O=C(Nc1ccc2c(c1)COC2)c1ccccc1-n1cnnn1 +Cc1cc(NC(=O)C2CCN(C(=O)C3CCCCC3)CC2)no1 +CN(C)S(=O)(=O)N1CCC(Oc2ccc(C#N)cc2)CC1 +O=C(NCC1COc2ccccc2O1)c1ccnc(-n2ccnc2)c1 +Nc1c(C(=O)Nc2ccccc2)nnn1Cc1ccccc1 +O=C(Nc1ccccc1N1CCCC1=O)c1csnn1 +COc1ccc(F)c(CNC(=O)c2cnc(C)[nH]c2=O)c1F +N#Cc1cccc(CS(=O)(=O)NCCCO)c1 +C=C(C)CN(CC)C(=O)C(c1ccccc1)N(C)CC +CC(Sc1nccn1C)C(=O)NCC(F)(F)F +CS(=O)(=O)c1nccn1Cc1ccccc1Cl +Cc1ccc(NCCCCO)cc1Br +CC(C)CNc1nc(C(=O)Nc2ccccc2O)cs1 +c1ccc(C2c3cccn3CCN2CC2CCOC2)cc1 +COc1nccnc1N1CC2CCC(C1)N(CC(=O)N(C)C)C2=O +COCCOc1cccc(NC(=O)N(C)Cc2ccncc2)c1 +COc1ccc(NC(=O)NCC2CCC2)cc1OC +CCn1nc(C)c(CN(C)C(=O)C2CCCO2)c1C +COc1ccc(C(=O)Nc2ncccc2CO)cc1OC +O=C(Nc1ccc(C(F)(F)F)cc1)c1cncs1 +CC(=O)c1c(C)[nH]c(C(=O)C(C)OC(=O)c2ccc(F)cc2F)c1C +Cc1nccc(CNC(C)c2cccc(C(F)(F)F)c2)n1 +Cn1ccc(C(=O)Nc2cccc3cnccc23)cc1=O +Cc1ccc(CNC(=O)NC(C)CN2CCOCC2)n1C +O=C(CCc1nc2ccccc2[nH]1)NCC1CC2C=CC1C2 +C=C(C)CN(CC)C(=O)Cn1c(=O)cnc2ccccc21 +CCC(C)N(C)C(=O)NCc1cccc(NC(=O)c2ccncc2)c1 +Fc1ccc2c(c1)CCN(CCn1cc(Br)cn1)C2 +C=CCN(Cc1cccc(OC)c1)C(=O)c1ccc(C)[nH]c1=O +CCn1nc(C)cc1C(=O)N1CCC2OCCC2(COC)C1 +O=C(NCCc1csc(-c2ccc(F)cc2)n1)c1ccco1 +COc1ccc(COC(=O)c2ccc(-n3ccnn3)cc2)cc1OC +CC(C)(CO)NC(=O)C1(c2cc(-c3ccccc3F)on2)CC1 +CC(=O)c1cc2c(cc1NC(=O)CSc1n[nH]c(N)n1)OCO2 +Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCCCC3)cc1 +CCc1n[nH]c(-c2cccc(NC(=O)N(C)C)c2)n1 +COc1ccc(NS(=O)(=O)Cc2ccc(F)cc2)cc1OC +CC(=O)NCc1ccc(C(O)c2ccccc2)cc1 +Cc1ccc(-c2ccc(=O)n(CCC(=O)NC3CCCC3)n2)cc1 +CN(C)c1ccccc1-n1ccnc1C(=O)NC(C)(C)C +O=C(NC(C(=O)N1CCCC1)c1ccccc1)c1cccc2ccnn12 +Cc1ccc2c(c1)NC(=O)C(CC(=O)N1CCc3ccccc3C1)O2 +CCSc1ccc(NC(=O)N(Cc2ccccn2)C2CC2)cn1 +COC(=O)CC(C)Sc1nc2ccccc2[nH]1 +CCc1ccsc1C(=O)N1CCCC(N2CCNC2=O)C1 +CCOc1ccccc1C(=O)N1CCN(C(C)=O)CC1 +Cc1ccc(NC(=O)C2CCC(=O)N2)cc1OCC(F)F +COc1ccccc1NC(=O)c1n[nH]c2c1CCc1ccccc1-2 +COc1cccc(CC(=O)Nc2cc(C)cc3cccnc23)c1 +Cc1nn(-c2cc(Oc3ccc(F)cc3)ncn2)c(N)c1C#N +COc1ccccc1OCC(O)CNc1cccc(F)c1 +COc1ccc(C)cc1NC(=O)n1ncc2ccccc21 +COc1ccccc1NC(=O)C(C)Sc1nc(C)cc(N)n1 +O=C(CSc1ncccn1)c1ccc(Br)cc1 +Cc1cc(=O)[nH]cc1-c1ccc(C(=O)NCc2ccco2)s1 +CCNC(=O)c1cccc(CNC(=O)N2CC(C)OC(C)C2)c1 +O=C(NCCOCC(F)(F)F)NC1CCN(c2ccccc2)CC1 +COc1cccc(CNc2ncn[nH]2)c1OCc1ccccc1 +COc1cccc(CC2(CO)CCCN(c3cccc(C#N)n3)C2)c1 +c1ccc(N2CCOCC2)c(CNc2ccc3[nH]ncc3c2)c1 +CNC(=O)c1cc(-c2ccncc2)nc2ccc(Br)cc12 +Cc1nn2cc(C(=O)NCC(=O)NCc3ccc(F)cc3)nc2s1 +COCCCCNc1ccc(C(=O)N2CCCCC2C)cc1C +COCc1ccc(S(=O)(=O)NCc2ccc(F)cc2)cc1 +Cc1csc(N2CCCN(Cc3ccc(C)s3)CC2)n1 +COc1cccc(C(=O)N2CCCC2C2CCCC2)c1F +COc1ccccc1NC(=O)Nc1ccccc1C(C)=O +COc1ccc2cc(CNC(=O)C(CC(C)C)NC(N)=O)ccc2c1 +CCC(C)C(C)NC(=O)c1csc(-c2cnn(C)c2)n1 +O=C(NC1CC1)C1CCN(c2nc3ccccc3s2)CC1 +COC(=O)c1c(NC(=O)c2cc(F)c(F)cc2Cl)c(C)nn1C +Cc1nnc(NC(=O)CSc2cccc3cccnc23)s1 +CC(OC(=O)c1cnn(-c2ccc(Cl)cc2)c1)c1ccccn1 +CCc1noc(COc2cc3cnccc3cc2OC)n1 +CCC(C)C(C)NC(=O)NCc1ccc(NC(=O)c2ccco2)cc1 +COc1ccc(C)nc1NC(=O)c1ccnc(OC2CCC2)c1 +CCCNS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 +Cc1cc2c(=O)n(CC(O)c3cccc(Cl)c3)cnc2s1 +O=C(C1CCN(c2ccc3ccccc3c2)C1=O)N1CCCC1 +Cc1c(C(=O)Nc2ccc(C(N)=O)cc2)nnn1Cc1ccccc1 +COc1cc(F)ccc1NC(=O)c1ccc(Br)cn1 +CCn1c(C)cc(C(=O)Nc2nc(C)cs2)c1C +Cc1ccc(C(=O)c2c(F)c(F)c(F)c(F)c2F)nc1 +Cc1ccc(C(=O)N(C)CC(=O)N2CCNCC2)n1C +O=C(Nc1nnc(C2CC2)s1)c1ccc(N2CCOC2=O)cc1 +CCOc1ccccc1NC(=O)CSc1nnc(C)s1 +O=C(NCCS(=O)(=O)N1CCOCC1)c1ccc(O)c(Cl)c1 +Fc1ncccc1C1NCCc2ccc(C(F)(F)F)cc21 +CC(CNC(=O)NCc1cccc(N(C)C)c1)Oc1ccccc1 +CN(CCOCC1CC1)C(=O)Nc1cc(F)c(F)c(F)c1 +Cc1ccc(NC(=O)NCC(O)c2ccc(C)o2)cc1 +Cc1ccc(N2CCCC2COC(=O)c2ccn3cncc3c2)nn1 +O=C(NCc1cccc(CO)c1)Nc1cnn(-c2ccccc2)c1 +CCOC(=O)c1ccc(S(=O)(=O)N(C)Cc2cc(C)on2)cc1 +COc1cc(C(=O)Nc2ccnn2Cc2cccc(Cl)c2)on1 +CCn1nccc1C(=O)Nc1nnc(-c2cccc(OC)c2)o1 +CC1CCC(C)N1C(=O)NCCCOCc1ccco1 +COc1ccc(OC(C)C(=O)N2CCOC(C)(C)C2)cc1 +CC(=O)c1c(Oc2ccncn2)ccc2ccccc12 +CN(C)c1ccccc1NC(=O)NCc1ccccc1-n1ccnc1 +O=C(c1ccc(Cn2cnnn2)cc1)N1CCc2c(nc[nH]c2=O)C1 +Cc1cc(N2CCCC2CCNS(C)(=O)=O)ncn1 +CN(CCNS(=O)(=O)c1ccccc1)c1ccccc1 +CCc1cccc(NC(=O)COc2nc(C)nc3ccccc23)c1 +Cc1cc(CNc2ccn(C)n2)ccc1-n1cncn1 +COc1cc(N)c2ccnc(C(=O)NC(C)(C)C)c2c1OC +CN(Cc1ccc(OC(F)F)cc1)CC(O)c1c(F)cccc1F +Cc1c(C(=O)NC(C)c2ccc(OC(F)(F)F)cc2)cnn1C +COc1ccc(OC)c(CCNC(=O)NCC(F)(F)F)c1 +Cc1nc(N2CCN(c3ncccn3)CC2)nc2c1C(=O)CCC2 +CC1CCCN(C(=O)Cn2cc(C(F)(F)F)ccc2=O)C1 +O=C1CCc2ccc(C(=O)NCc3ccccc3)nc2N1 +CN(C)c1cccc(Oc2c(N)ccc(F)c2F)c1 +CCc1oc2ccccc2c1CN(C)C(=O)c1ccc(C)[nH]c1=O +Cc1csc(NC(=O)c2cnn(-c3ccccc3C)c2C2CC2)n1 +COc1cccc(NC(=O)c2c(C)[nH]c(C(C)=O)c2C)c1 +CC(C)N1CC(C(=O)NCc2ccccc2OC2CCCC2)CC1=O +CC(C)(C)OC(=O)N1CCCCC1CS(=O)(=O)c1nccs1 +N#Cc1ccc(CNCCc2ccc(-n3cccn3)cc2)cc1 +COc1ccccc1S(=O)(=O)NCc1ccc(F)cc1 +COc1cc(C)ccc1OC(=O)Cc1csc(-c2cccnc2)n1 +Cc1ccsc1C(=O)OCC(=O)Nc1ccc(Cl)cn1 +COC(=O)c1cc(-c2cccnc2)nc(N2CCCC(C)C2)n1 +CCOc1ccc2cc(C(=O)NC(C)c3ccccc3)c(=O)oc2c1 +CCCc1cc(C(=O)N2CCN(CCc3ccccc3)CC2)n(C)n1 +O=C(Cc1ccccc1O)NCCCOc1cccc2cccnc12 +CCOC(=O)C1CCCN1C(=O)CC1CCCC1 +O=c1c(=Cc2ccc(F)cc2)sc2nc(-c3ccco3)nn12 +CCN(Cc1cccc(C)c1)C(=O)CCNC(=O)c1cccs1 +CCCN1CCN(S(=O)(=O)c2cc(Cl)ccc2Cl)CC1 +O=C(CC1COC2CN(c3ncccn3)CC12)N1CCCC1 +CC(C)Cc1ccc(C(O)CCCC(=O)N(C)C)cc1 +CC(=O)NC1CCCN(C(=O)c2cccc(C)c2O)C1 +O=C(Cn1c(C2CC2)nc2ccccc21)Nc1cccc(Cl)c1 +O=C(CC1CCCC1)N1CCC(Oc2ccccn2)CC1 +N#Cc1ccccc1CN1CCN(c2ccc(O)cc2)CC1 +CCC(=O)Nc1nnc(Cc2ccc(Cl)cc2)s1 +CCc1ccc(C(=O)NCc2cccc(S(=O)(=O)NC)c2)o1 +Cc1cc(C(=O)NCCCn2cnc3ccccc32)c(C)o1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1cc(Cl)c[nH]1 +CC(C)Cn1nc(C(=O)OCC(F)F)c2ccccc2c1=O +CCOCC(=O)OCc1noc(-c2ccc(F)cc2)n1 +CC(C)NC(=O)c1nsc(C(=O)NC2CC2)c1N +COC(=O)c1sccc1S(=O)(=O)Nc1ccccc1 +O=C(CCc1cccnc1)Nc1nnc(C2CCCCC2)s1 +CC(C)n1nccc1NC(=O)N(C)Cc1nc2ccccc2s1 +COc1ccccc1NC(=O)C(C)CS(=O)(=O)N1CCNCC1 +C=CCN1CCn2ncc(C(=O)NCc3ccc4c(c3)OCO4)c2C1 +COc1ccccc1S(=O)(=O)Oc1cccc(F)c1 +CC(=O)c1ccccc1C(=O)N1CC(c2ccsc2)CC1C +CCCNC(=O)C(C)NC(=O)C(C)Sc1nncs1 +Cc1nc(C)c(-c2nn3c(-c4ccc(F)cc4)nnc3s2)s1 +CCc1nnc2n1-c1ccc(Br)cc1NC2 +CC=CCOC(=O)CCc1nc2ccccc2s1 +O=C(Nc1ccccc1O)C12CC3CC(CC(O)(C3)C1)C2 +Cc1c(NCC(=O)NCC2CCCO2)cccc1NC(=O)C1CC1 +COc1ccc(S(=O)(=O)NC(C)Cc2ccsc2)cc1 +CN(CCOc1ccccc1F)C(=O)CCC(=O)N1CCOCC1 +N#Cc1cccc(CNC(=O)NCC2(c3ccccc3F)CC2)c1 +CNS(=O)(=O)c1ccc(CCC(=O)N2CCOCC(O)C2)cc1 +C#Cc1cccc(N(Cc2ccccc2)C(=O)C2CCOCC2)c1 +CCC(C)(C)NC(=O)C(C)S(=O)(=O)c1ccc(C)cc1 +CC1CCN(C(=O)CCCNC(=O)c2ccc(F)cc2F)CC1 +O=C(CCn1ccc2ccccc21)N(Cc1cccnc1)C1CC1 +Cc1cccc(C)c1NC(=O)CCSc1ccccc1 +CCn1cc(C(=O)NCc2ncoc2C)c(=O)c2cc(Cl)ccc21 +O=C(NCC(O)c1ccco1)Nc1ccc2c(c1)CCC2 +COc1cc(-c2noc(C)n2)ccc1OCC1CCC1 +CNC(=O)c1cc2cnn(C3CCCCCC3)c2nc1N +Cc1cc(C)c(N2C(=O)CCS2(=O)=O)c(Cl)c1 +COc1ccc2c(c1OC)C(=O)OC2Nc1cc(C)ccc1O +CCOc1ccccc1N1CC(C(=O)Nc2cc(C)on2)CC1=O +CN(Cc1nnc(-c2ccccc2)o1)C(=O)c1ccccc1 +COC(=O)c1ccsc1NC(=O)c1ccccc1Cl +O=C(NCc1nnc2n1CCC2)c1cc(-c2cccc(Cl)c2)no1 +C#CCN1CCN(C(=O)NCCC2=CCOCC2)CC1 +O=C(CSc1nnc(-c2cccs2)o1)N1CCCC1 +COc1ccc(CC(C)CNC(=O)c2ccc3nnc(C)n3c2)cc1 +CC1(C)CC(=O)c2cn3c(nc2C1)nc1ccccc13 +COc1ccc(OC)c(C(C)NS(=O)(=O)c2cccc(F)c2)c1 +COc1ccc(C(C#N)N(C)C(=O)CC(C)C)c(OC)c1 +O=C(NCCCC1CCOC1)Nc1cccc(OC(F)(F)F)c1 +COc1ccc2c(c1)CCCC2CNC(=O)C(C)OC +C#CCn1c(-c2ccc(Br)cc2)ccc(C#N)c1=O +CCC(Sc1nnc(C)s1)C(=O)Nc1ccc(C(C)=O)cc1 +O=C(CNc1ccc(F)c(Cl)c1)N1CCOCC1 +CC(=O)Nc1ccc(NC(=O)c2ccc(-n3cncn3)nc2)cc1 +CN(Cc1nc2ccccc2s1)c1cc(=O)n2ccccc2n1 +Cc1cccc(CN2CCN(S(=O)(=O)c3ccccc3)CC2)c1 +Cc1cc(C)cc(C(=O)Nc2ccc(S(=O)(=O)C(F)F)cc2)c1 +CCc1cnc(CNC(=O)NC2(c3nccs3)CCCC2)s1 +COc1ccc(NC(=O)Cn2c(=O)n(C)c3ccccc32)cn1 +Cc1cc(C(=O)OCC(=O)Nc2ccccc2C(F)(F)F)c(C)o1 +CCCn1nnnc1COc1cc2oc(=O)cc(C)c2cc1Cl +c1ccc(CCn2ccnc2-c2ccc(-c3cc[nH]n3)s2)nc1 +CCCOc1ccc(C(=O)N2CCC(C(N)=O)C2)cc1OCC +N#CCCN(CCC(F)(F)F)S(=O)(=O)c1cccnc1 +CNc1cnn(-c2cc(Cl)cc(Cl)c2)c(=O)c1 +CCCC(=O)Nc1cccc(CNC(=O)NCc2ccncc2)c1 +CCCOc1cc(C)ccc1NC(=O)NCCn1cccc1 +Cc1ccc(CNC(=O)NCC2CCOC2)s1 +COC(=O)c1cccc(-c2cn3nc(N)nc3cc2C)c1 +CCc1ccc(CNC(=O)c2cccc(OC)c2F)s1 +CC(Sc1nc2ccccc2s1)C(=O)N(C)Cc1cnccn1 +CCCS(=O)(=O)NCc1cn2cc(Cl)ccc2n1 +N#Cc1cccc(NC(=O)COc2cccc3c2CCC3=O)c1 +CCc1c(C)nc2n(c1=O)CC(C(=O)NCc1ccco1)CS2 +COc1cccc(C(=O)N2CCC(C)CC2)c1OC +Cc1cc(C(=O)Nc2ccc(N3CCCC3)cn2)on1 +COC1C2CCC1CN(c1cc(C(C)C)nc(N)n1)C2 +CCCc1nc2c3ccccc3n(CC(=O)c3ccccc3)c(=O)n2n1 +C=CCn1c(SCc2n[nH]c(=O)[nH]2)n[nH]c1=O +c1cncc(COC2COC3(CCCN(c4cnccn4)C3)C2)c1 +Cc1noc(CNC(=O)NC2CCCOc3cc(F)ccc32)n1 +Cc1nnsc1C(=O)NCc1cccc(Oc2ccccn2)c1 +COc1ccc(Nc2nc(NCCCO)nc3c2cnn3C)cc1 +CNc1snc(C)c1C(=O)Nc1ccc(O)cc1F +Cc1cc(C)c2nc(C)cc(C(=O)NCCNc3cccnc3)c2c1 +Fc1ccccc1C(Nc1ncccn1)Nc1ncccn1 +CCCC(=O)Nc1ccccc1NC(=O)c1ccc2c(c1)OCO2 +Cc1ccsc1C(=O)N(C)Cc1ccc2c(c1)OCCO2 +COc1ccccc1CC1CCCN1Cc1cn(C)nc1C +CCCCS(=O)(=O)Nc1ccc(C(=O)Nc2ccccc2)cc1 +O=C1Nc2ccc(F)cc2C1NC1CN2CCC1CC2 +CC(=O)N1CCN(C(=O)c2cc3c(F)cccc3s2)CC1 +CC(=O)Oc1ccc(C=Cc2cc(O)cc(O)c2)cc1 +CN(C)C(=O)COc1cccc(CNC(=O)c2cc(F)cc(F)c2)c1 +CC(C)C(Sc1nncn1C1CC1)C(=O)NC1CCCCC1 +CCC1CCCN(S(=O)(=O)CCn2cnc3ccccc32)C1 +Cc1nc(C2CCCC2)sc1C(=O)Nc1cn(C)c(=O)n(C)c1=O +COC(=O)c1ccc(C(=O)N(C)C2CCCc3ccccc32)cc1 +O=C(NC1CCCc2[nH]c(=O)ccc21)c1n[nH]c2ccccc12 +COc1ccc(NC(=O)N(C)Cc2ccc(OC)c(OC)c2)cc1F +Cc1oc(C)c(C(=O)NCCc2ccc(-n3cccn3)cc2)c1C +O=S(=O)(NCCCSc1ccccc1)c1ccccc1 +O=C(c1nccn2ccnc12)N1CCCC2(CCCCC2)C1 +CCC(=O)Nc1cccc(C(=O)OCC(=O)c2ccc(F)cc2)c1 +Cc1cc(C(=O)N2CCC(c3cn[nH]c3)CC2)[nH]n1 +CC(=O)N1CCC(NC(=O)N(C)Cc2ccsc2)CC1 +COc1ccc2c(c1)CN(Cc1nc3c(cnn3C)c(=O)[nH]1)CC2 +CN1CC(c2nc(-c3ccc(-c4ccccc4)cc3)no2)CC1=O +CCOc1ccc(C(=O)Nc2ccccc2N2CCCC2)cc1OC +O=C(NCCc1coc(-c2ccc(F)cc2)n1)NC1CCC(O)CC1 +O=C(NCCCc1ccccc1)NCC1(CO)CC1 +O=C(c1ccc(-c2nnc(-c3ccccc3)o2)cc1)N1CCOCC1 +COC(=O)c1ccc(C2NCCc3ccccc32)cc1 +COC(=O)c1ccc(CNC(=O)c2cc(=O)c3ccccc3o2)cc1 +COc1ncccc1CNC(=O)N1CCN(c2ncccn2)CC1 +CCC(=O)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1 +NC(=O)Nc1ccc(NC(=O)c2cc(Cl)cc3cccnc23)cc1 +O=C(Cn1nnc(-c2ccc(F)cc2)n1)Nc1cccc(F)c1 +CN(C)C(=O)CN1CCC2(CCN(c3cccc(F)c3)CC2)C1=O +COCC1CCN(c2nncc(-c3cccc4ccccc34)n2)C1 +CCOC(=O)C1(NC(=O)c2cccc(COC)c2)CCCC1 +CCC(C)(C)NC(=O)c1ccc(NCc2nc(C)no2)cc1 +O=C(Nc1ccccc1)c1cccc(S(=O)(=O)N2CCCC2)c1 +Cc1csc(SCCC(=O)Nc2ccccc2N)n1 +CCOc1nc(C)cc2c(NCc3ccncc3)cccc12 +O=C(CSc1ccc2c(c1)OCCCO2)NCc1ccco1 +COCC1CN(C(=O)c2ccoc2)Cc2cnn(C)c21 +O=C(NC1(c2nnn(CC3CCCO3)n2)CCCC1)c1ccccc1 +CCOC(=O)c1cccc(Nc2nc(N)nc3[nH]cnc23)c1 +CCN(Cc1cccc(NCc2noc(C)n2)c1)C(C)=O +CCCn1nc(C(=O)Nc2ccc(C(=O)NC)cc2)ccc1=O +O=C(NCc1ccc(Br)cc1)c1ccccc1 +Nc1onc(C2CC2)c1-c1ccc2c(c1)OCCO2 +CC(C(=O)NC1CC1)N1CCN(C(=O)N2C(C)CCCC2C)CC1 +CCOC(=O)c1cc(C(=O)Nc2ccc3c(c2)OCO3)nn1C +CCn1ccc(C(=O)N2CC(=O)Nc3ccccc32)n1 +COc1ccc(F)cc1NC(=O)CNC(=O)CC(C)(C)C +COCCN1CCCC(O)(CN2CCn3nc(C#N)cc3C2)C1=O +COC(=O)C(C)CNC(=O)Nc1cnn(-c2ccccc2Cl)c1 +Cc1ccc2[nH]cc(NC(=O)N3CCCC3)c(=O)c2c1 +Cn1c(C(O)c2ccc3c(c2)OCO3)nc2ccccc21 +Cn1nc(CNC(=O)c2cc(=O)c3ccccc3o2)cc1C1CC1 +CCSc1nnc(NC2OC(=O)c3ccccc32)s1 +Cc1ccc(CC(=O)N(CCC#N)CCC(F)(F)F)cc1 +Cc1ncc(CNC(=O)c2cccc(-n3cnnn3)c2)s1 +CC(C)(C)C(NS(=O)(=O)Cc1ccon1)c1ccc(F)cc1F +Cc1ccc(C2NC(=O)c3ccccc3N2)cc1C +COc1nc2ccn(CCC3CCCOC3)c(=O)c2cc1C#N +C=CCNc1cc(-c2cncc(-c3cccs3)c2)nc(C)n1 +Cc1cnn(CC2CN(CC(=O)N(C)Cc3ccccc3)CCO2)c1 +N#Cc1ccc(Cn2cnc3ccc(Cl)cc3c2=O)cc1 +CCN(CC(F)(F)F)C(=O)Nc1cccc(CC(N)=O)c1 +Cc1c(C(=O)NC2CC2)nnn1Cc1ccccc1 +CCc1ccccc1NC(=O)CN1C(=O)COc2ccccc21 +Cn1ncc(N)c1N1CCCC(NC(=O)OC(C)(C)C)C1 +c1cc(-c2noc(CCN3CCOCC3)n2)cs1 +N#Cc1cc(C(=O)N2CCCC(c3ccn[nH]3)C2)ccc1N1CCCC1 +CNS(=O)(=O)c1cccc(C(=O)Nc2nc3ccccc3s2)c1 +CCN(CC)C(=O)CN1CCc2ccc(Cl)cc2C1 +CCN(CC)S(=O)(=O)N(C)Cc1ccc(SC)cc1 +CCC(NC(=O)c1csc(C)n1)c1ccccc1OC +Cn1c(=O)n(C)c2cc(NC(=O)c3ccc(F)cc3)ccc21 +C=CCc1ccccc1OCc1nnnn1-c1ccccc1 +CC(C)(C)NC(=O)CCSc1nn2cnnc2o1 +Cc1nc2ccccc2n1CC(O)c1cc(F)ccc1F +Cc1cccc(C)c1NC(=O)CCn1[nH]c(=O)c2ccccc2c1=O +CC(=O)N1CCCN(C(=O)C(C)Oc2cccc(C#N)c2)CC1 +CCc1nc(CC(=O)Nc2cc(F)c(OC)c(F)c2)cs1 +CNC(=O)c1onc(S(=O)(=O)c2ccccc2)c1N +O=C(NCc1noc(Cc2ccccc2)n1)c1ccccc1F +COc1cc(C#N)ccc1OC(=O)CSc1ccc(F)c(F)c1 +CNC(=O)c1cccc(NC(=O)Nc2ccc(C)cc2)c1C +CCC(C)NS(=O)(=O)Cc1cccc(NC(=O)c2ccco2)c1 +CCCc1cc(C(=O)N2CCC(c3nc[nH]n3)CC2)no1 +CS(=O)(=O)N1CCN(C(=O)c2ccc(-n3cncn3)nn2)CC1 +COc1ccc(C(=O)Nc2cc(NC(=O)C3CC3)ccc2C)cc1F +COc1cc(Cl)ccc1CNC(=O)C1CCC(=O)N1 +COc1ccc(C(C)NC(=O)NC(C)c2ccccn2)cc1F +CCCCN(C)C(=O)CN1CC(CC)Oc2cccc(N)c21 +CCCN(C)C(=O)Nc1cc(C(=O)OC)ccc1C +CN(C)C(=O)N1CCC2(C1)C(=O)Nc1ccccc12 +Cc1sc2ccccc2c1S(=O)(=O)Nc1cnn(C)c1 +Cc1[nH]c(=O)[nH]c(=O)c1S(=O)(=O)NCc1cccnc1 +CCC(=O)N1CC(=O)Nc2cc(S(C)(=O)=O)ccc21 +CC(=O)Nc1cc(S(=O)(=O)Nc2c[nH]nc2C)ccc1C +CCN(Cc1c(C(=O)OC)nnn1-c1nonc1N)c1ccccc1 +COc1ccc(-n2nnc(C(=O)N3CCOCC3)c2C)cc1Cl +O=C(CCc1ncc(-c2ccc(F)cc2)o1)NCC1CCCO1 +COC(=O)CC(C)NC(=O)c1cc2cccc(Br)c2o1 +Cc1cccc(-n2ncnc2CCC(=O)NC2CCCC2)c1C +Cc1cc(Cl)ccc1OC(C)C(=O)NCc1ccccn1 +C=CCc1cc(C(=O)Nc2ccc3c(c2)COC3)cc(OC)c1OC +Cc1nc(C2CC2)nc2sc(C(=O)NCC(C)C)c(C)c12 +CC(C)CC(C(=O)NCCNC(N)=O)N1CCCCC1=O +CCOc1ccc(NC(=O)NCc2ncc[nH]2)cn1 +CS(=O)(=O)N1CCOCC2(CN(Cc3nccs3)CCO2)C1 +CN(CCc1c(F)cccc1Cl)C(=O)CCC#N +Cn1nccc1NC(=O)c1ccc(O)c(Cl)c1 +Cc1ccc(S(=O)(=O)NC(C)C(=O)NCc2ncn(C)n2)cc1 +COc1cc(C(=O)NCC2CCCO2)ccc1OC(F)F +COCC(=O)N1CCn2c(Cn3cncn3)cnc2C1C +CC(NC(=O)c1ccc(Cl)cc1)C(=O)N(CCC#N)CCC#N +NS(=O)(=O)N1CCN(C(=O)c2ccc3[nH]cnc3c2)CC1 +COc1ccnc(NC(=O)c2ccc(-n3ccnc3SC)cc2)c1 +COc1ccc(CN(C)C(=O)Nc2cc(C)on2)cc1OC(F)F +Cc1csc(C2CCCN2C(=O)C2CCCC2)n1 +CCOC(=O)CNC(=O)COc1ccc(F)cc1F +CC(C)NC(=O)c1coc(NC(=O)c2ccccc2)n1 +Cc1nn(C)c(C)c1-c1ccnc(NC2CCC2)n1 +CC(NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)NCCCO +O=C(CCC1CCCC1)NC1CCCN(Cc2ccccc2)C1=O +COc1cc(NC(=O)c2ccccc2)ccc1N1CCCC1=O +C#CCOc1ccc(NC(=O)c2ccc(CC)o2)cc1 +CCCCn1ncc(C)c1NC(=O)c1ccc(OC)c(F)c1 +CC(C)Sc1nnc(-c2ccccc2F)n1N +CN(C)c1nc2nonc2nc1N(C)Cc1nc2ccccc2o1 +Cc1cc(S(=O)(=O)N(C)C)cc(NC(=O)C2CCC2)c1C +Cc1cc(C(=O)N(C)Cc2ccccn2)ccc1S(N)(=O)=O +CCOCC1CCCN(C(=O)c2ccc(N3CCCC3=O)cc2)C1 +O=C(Nc1ccc2oc(C3CC3)nc2c1)Nc1cnn(CC(F)F)c1 +COC(=O)CC(NC(=O)Nc1cnccc1C)c1ccccc1Cl +O=C(NC(CC(F)(F)F)c1ccc(F)cc1)c1cnccn1 +COc1ccc(OC)c(CN(C)C(=O)c2ccc(C)c(OC)c2)c1 +Cc1ccc(CN(C)C(=O)NCC2CCOC2)c(C)c1 +COc1cccc(Cn2c(-c3nonc3N)nc3ccccc32)c1 +CCc1cc(CNC(=O)N2CCOC3(CCCC3)C2)[nH]n1 +O=C(NCC1CCC2C1OCCN2Cc1ccncc1)c1ccco1 +CCN(CC)C(=O)C1(O)c2ccccc2NC(=O)N1c1ccccc1 +NC(=O)CN1CCN(CC(=O)NCc2cccc(Cl)c2)CC1 +CC1CN(C(C)CNC(=O)C2CC(=O)Nc3ccccc32)CC(C)O1 +COc1ccccc1C1(CNC(=O)NC(C)C)CCOCC1 +Cc1ccccc1NC(=O)COC(=O)c1cc(F)c(F)cc1F +CCOc1ccccc1-n1c(CCC(F)(F)F)n[nH]c1=O +CSc1ccsc1C(=O)Nc1cccc(-c2cn[nH]c2)c1 +Cc1ncc(CN(C)C(=O)Nc2ccc(-c3nccs3)cc2)s1 +CC(Oc1ccc(Cl)cc1)C(=O)Nc1ncc(C(N)=O)s1 +O=C(CCc1ccsc1)N1CCN(CC(=O)N2CCCC2)CC1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3nncs3)cc2)n1 +O=S(=O)(C1CC1)N1CC(c2nc3ccccc3[nH]2)C1 +CC(C)(C#N)NC(=O)C1CCCN(c2ncccc2C(F)(F)F)C1 +c1cc(-c2nnc(SCc3nc(-c4ccoc4)no3)o2)ccn1 +Cc1ccc(-c2cc(CNC(=O)c3cn4ccccc4c3N)no2)cc1 +CCCC(=O)N1CCCC1C(=O)Oc1ccc(C(C)=O)cc1 +CC(=O)Nc1cccc(NC(=O)COc2ccccc2F)c1C +COC(=O)C(C)N1CCN(C(=O)COc2ccc(F)cc2)CC1 +CSc1cccc(NC(=O)NCc2cnn(C)c2)c1 +CCc1nnc(NC(=O)CC(NC(C)=O)c2ccc(OC)cc2)s1 +CCOC(=O)C(NS(=O)(=O)c1ccc(C)cc1)C(C)O +Cc1ccc(CNC(=O)Cn2nnc(-c3cccs3)n2)cc1 +CCCN(CCO)C(=O)c1cc2ccc(OCC)cc2[nH]1 +Cc1ccccc1C(=O)NCC(=O)Nc1ccc2c(c1)OCCO2 +O=C(CCNS(=O)(=O)c1cccnc1)OC1CCCC1 +Cc1ccc(NC(=O)CSc2ccncc2)cc1Br +CCc1ccc(-c2nc(C3(NC(C)=O)CCCCC3)no2)o1 +CCOCc1ccccc1NC(=O)NC(C)C(C)CO +O=C(Nc1ccc2[nH]ccc2c1)c1ccc(-n2cccn2)c(F)c1 +O=C(Cn1cnc2ccccc2c1=O)NCC1CC2CCC1C2 +Nc1cc(C(=O)N2CCCC2CCCO)ccc1Cl +Cc1ccc2c(CSc3nccn3C)cc(=O)oc2c1 +Cc1cc(=O)oc2cc(NC(=O)CC3C=CCC3)ccc12 +Cc1nc2cc(C(=O)Nc3cc(C(C)C)n[nH]3)ccc2n1C +CCOC(=O)CN(C)C(=O)c1ccc(OC)cc1O +CN(Cc1ccccc1)CC(C#N)C(O)c1ccncc1 +O=c1ccc(-c2ccco2)nn1CCC1OCCO1 +OC(c1cccc(Cl)c1)c1nc(Cc2ccccc2)n[nH]1 +CCOc1cc(NCC2CCCO2)nc(CC(C)C)n1 +Cc1ccc(CN2C(=O)OCC2CO)c2ccccc12 +c1ccc(N2CCC3OCCCC3(COCc3cccnc3)C2)cc1 +Cc1cc(C(=O)Nc2ccc(F)c(-n3cccc3)c2)n(C)n1 +CN(CCc1noc(-c2ccccc2)n1)C(=O)c1ccccc1 +O=C(N=c1[nH]c2ccccc2[nH]1)c1ccnc(-n2cncn2)c1 +CCCNC(=O)NCc1cccc(C(=O)NC(C)CC)c1 +CCN(CC)C(=O)CCC(=O)N1CCC(N(C)C(C)=O)CC1 +Cc1n[nH]c(SCCn2c(=O)oc3ccccc32)n1 +COc1ccc(Cl)cc1NC(=O)NC(CCCO)c1ccccc1 +CC1CCCN(S(=O)(=O)NCc2ccc(Cn3cncn3)cc2)C1 +Cc1cc(C)nc(Nc2nc(C(=O)N3CCCCC3)cs2)n1 +COc1ccccc1NC(=O)CN1C(=O)CSc2ccccc21 +Cc1n[nH]c(=O)c(C(=O)N2CCC(C(O)c3ccccc3)CC2)c1C +Cc1ccc2ncc(C(=O)Nc3nccs3)n2c1 +O=C(Nc1nnc(Cc2ccccc2)s1)N1CCOCC1 +CNc1cccc(C(=O)Nc2ccc(Cl)cc2Cl)n1 +O=C(NC1CCCCCC1)c1cccnc1N1CCOCC1 +COc1ccccc1C(=O)CNc1ccc(C#N)cc1 +Cc1ccc(-n2c(C)c(C)c3c2N=CN2CCS(=O)(=O)N=C32)cc1 +Cc1ccc(C(=O)NCCCn2cnc3ccccc32)c(C)c1 +CCCN(CC(=O)OC)C(=O)c1cccn1C1CC1 +Cc1cccc(C(=O)NC2CC(=O)N(CCN3CCOCC3)C2)c1 +O=C(Cn1nnc(-c2ccccc2Cl)n1)N1CCCCCC1 +Fc1ccc(C2NCCc3ccc4[nH]ccc4c32)nc1 +CCOC(=O)c1nnsc1-n1nnc2ccccc21 +O=C1COc2ccc(C(=O)N3CCc4ccccc43)cc2N1 +O=C(NCCCc1ccccc1)Nc1cc(N2CCCC2)ncn1 +O=C(CCn1ccccc1=O)Nc1ccc(OC(F)F)c(F)c1 +Cc1ccc(S(=O)(=O)N2CCCCCC2c2ncon2)cc1 +Cc1ccc(-c2nc(CC(=O)OCC3CCC(=O)N3)cs2)cc1 +CC(C)(C)NC(=O)c1cccc(-n2ccnc2)c1F +COc1ccccc1CCC(=O)NCCN1CCOCC1 +COc1ccc(NC(=O)NCCC(=O)Nc2ccccc2C)cc1 +COC(=O)C1=C(C)C(C(=O)C(C)N2CCOCC2)=NC1C +O=C(CSc1ccccn1)Nc1nnc(-c2ccccc2)s1 +COc1cc(OC)c(-c2oc3ccccc3c(=O)c2O)cc1OC +O=C(Nc1ccc2[nH]ncc2c1)c1n[nH]c2cc(Cl)ccc12 +O=C(C1CCCC1)N1CCc2onc(-c3ccccc3)c2C1 +CC1CC(C)CN(S(=O)(=O)N(C)CCc2ccc(F)cc2)C1 +Nc1cccc(C(Cc2cccs2)C(=O)N2CCCCC2)c1 +O=C(Cn1cnc2c(sc3ncccc32)c1=O)NC1CCCCC1 +CCCn1nnc2cc(C(=O)NCc3ccc(Cl)cc3)ccc21 +COc1ccc(NC(=O)CSc2nn3cnnc3s2)c(C)c1 +CSc1cccc(NC(=O)c2ccccc2S(C)(=O)=O)c1 +O=C(NCc1cccnc1-n1cccn1)c1ccc[nH]c1=O +Cc1cc(=O)[nH]c2cc(NC(=O)c3cc4ccccc4oc3=O)ccc12 +CC(Oc1ccccc1C#N)C(=O)N1CCN(CC(C)(C)O)CC1 +O=C(Cn1c(=O)[nH]c2ccccc21)NCc1cn[nH]n1 +Cc1cc(C)cc(OCCNC(=O)c2cc(C)n[nH]2)c1 +COc1ncccc1C(=O)NCCc1ccc2c(c1)OCCO2 +Cc1cc(S(=O)(=O)NCc2ccon2)c(F)cc1F +CCN(CC)C(=O)Cn1cnc2sc(C)cc2c1=O +CCCc1cc(=O)n(CC(=O)Nc2ccc(C)c(C)c2)cn1 +Cc1cccc(OCC(=O)Nc2ccn(-c3ncccc3Cl)n2)c1 +C=CCSc1n[nH]c(=O)n1-c1cccc(C(F)(F)F)c1 +CC(=O)Nc1ccc(C(=O)N2CC(c3ccc(F)cc3)CC2C)cc1 +O=C(NCCC(=O)N1CCCC1)Nc1ccc(F)c(Cl)c1 +Cc1nc(CCNC(=O)Cn2ccc(=O)n(C)c2=O)cs1 +CC(=O)c1ccc(S(=O)(=O)NCc2ccc(C)cc2)cc1 +CCC(NC(=O)CCn1cc(C)cn1)c1cccs1 +CC(C)(O)CCc1cccc(C(=O)N(Cc2nccs2)C2CC2)c1 +O=C(Nc1ccc2c(c1)OCCCO2)c1cccc(F)c1 +COc1ccccc1C(C)N(C)C(=O)NCCNC(C)=O +COC(=O)Cn1cc(NC(=O)C(NC(C)=O)C(C)C)cn1 +CCCc1nc(CN2CCOCC2)sc1C(C)(C)O +CCCCC1NCCc2cc(Cl)c(OC)c(OC)c21 +CCS(=O)(=O)c1ccc(C(=O)OCC(N)=O)cc1 +CC(C(=O)NC1(C#N)CCCCC1)N1CCn2c(nn(C)c2=O)C1 +Cc1cc(-n2cc(C(=O)NCc3ccccc3Cl)nn2)ccc1F +Cc1cccnc1NC(=O)C1(C)Cc2ccccc2C(=O)O1 +COc1ccccc1C=CCN1CCC2(C1)OCCO2 +N#CCc1ccc(NC(=O)Cc2ccc(O)cc2)cc1 +COc1ccc(F)c(F)c1-c1nccn1CCc1cc(=O)[nH]c(C)n1 +CCCN(C)S(=O)(=O)c1cccc2c(N)cccc12 +CS(=O)(=O)N1CCCCC1C(=O)NCc1ccccc1F +O=C(CCSc1ccccn1)N1CCCc2cc(F)ccc21 +CC1(C)Cc2c(C#N)c(NCCO)nc(Cc3ccccc3)c2CO1 +Cc1ccc(S(=O)(=O)Nc2cnn(CC3CCCO3)c2)cc1C +C#CC(C)(CC)OCC(O)CN1CCN(c2ccccc2)CC1 +O=C(Nc1cc(-n2cccc2)ccc1F)C1CC(=O)N(C2CC2)C1 +Cn1ccc2c(cc(C(=O)NCCCc3ccccc3)n2C)c1=O +Cc1cccc(C(=O)N2CCc3sccc3C2)n1 +CC1CN(C(=O)C(NC(=O)c2ccco2)C(C)C)CCO1 +CCOC(=O)C(O)(c1c[nH]c2ccc(C)cc12)C(F)(F)F +O=C(NCC1(c2ccc(F)cc2F)CC1)N1CCC2(C1)OCCO2 +CC(=O)c1cccc(NC(=O)CNc2ccccc2)c1 +COc1ccc(N2CCCCS2(=O)=O)cc1OC +CCc1nn2c(C#N)c(-c3ccc4c(c3)OCCCO4)nc2s1 +CNS(=O)(=O)c1ccc(Cl)c(C(=O)Nc2ccccc2)c1 +COC(=O)c1sccc1CN1CCN(C(=O)c2ccccc2)CC1 +Cc1ccc(NCc2nc(C)c(C)s2)c(Br)c1 +O=C(C1CCCCC1)N1CCN(c2nnnn2-c2ccccc2)CC1 +COc1ccccc1CNC(=O)c1ccc(Cn2nc(C)cc2C)o1 +Cc1n[nH]c(C)c1CCC(=O)NC(C)c1ccc(Cl)cc1 +COC(=O)C(C)(C)NC(=O)CCc1ccc(F)c(F)c1 +CC(NC(=O)Nc1ccc(OCC2CCOCC2)cc1)C1CCCO1 +CCOC(=O)CSc1cc(C)nc(SCC)n1 +O=C(CSc1ccncc1)Nc1nnc(C2CC2)s1 +Cc1cc(CNC(=O)Cc2ccc(OCC#N)cc2)c(C)o1 +Cc1ccc(C(=O)Nc2cc(C(N)=O)ccc2C)s1 +COc1ccccc1-n1cnc2sc3c(c2c1=O)CCCC3 +O=C(CC1CC1)N1CCCC2(CC(Nc3nccs3)CO2)C1 +CN(C)C(=O)C1CCCN(c2cnn(C)c(=O)c2)C1 +Cc1cc(C(=O)CCC(=O)N(C)c2ccccc2)ccc1F +Cc1ccccc1NC(=O)C1CCCCN1C(=O)c1ccccc1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cc(C)n(CC)c1C +CC(COc1ccccc1C(F)(F)F)NC(=O)c1ccoc1 +Cc1nc(C)c(-c2nn3c(-c4ccccc4)nnc3s2)s1 +CC(=O)N1CCCC(=O)c2ccc3c(c21)CC(C)O3 +C#CCn1nc(CO)cc1-c1ccc(Cl)c(Cl)c1 +Cc1ccc(C(=O)N2CCN(CC(F)F)CC2)o1 +CC(=O)Nc1cccc(NC(=O)COc2cc(C)ccc2C)c1 +OCCC#Cc1cc(F)ccc1OCC(F)(F)F +CC1CN(C(=O)c2cc3ccc(F)cc3n2C)CC(C)O1 +CC(C)NC(=O)Cn1c(=O)oc2ccc(Cl)cc21 +COCC(C)Nc1ncnc(N2CCC(C)CC2)c1N +CCc1ccsc1C(=O)NCc1ccccc1OC +Cc1csc(N(CC(F)(F)F)C(=O)C2CCC2)n1 +COCCN(C(=O)c1cc(-c2ccc(C)s2)[nH]n1)C1CC1 +CN(Cc1nc(-c2ccncc2)no1)C(=O)c1ncoc1C1CC1 +COc1cc(Nc2ccc(C#N)cn2)c(OC)cc1Cl +Cc1cc(C)nc(N2CCC(C)(c3[nH]ncc3C)CC2)n1 +CCc1c(C)c2ccc(OC(C)=O)c(C)c2oc1=O +CC(C)(C)C(=O)Cn1cnc2cc(F)ccc2c1=O +Cc1ccc(SCC(=O)Nc2nnc(C(C)C)o2)cc1 +COc1ccc(-c2ccc(=O)n(Cc3cccc(C)c3)n2)cc1OC +O=C(OCCNc1cccnn1)c1ccc(-c2ccc(F)cc2)o1 +COc1cc(C)c(C)cc1S(=O)(=O)NCc1cc(C)oc1C +CC1CN(CCCNS(=O)(=O)c2cn[nH]c2)CC(C)O1 +OCc1cn(CCOc2cccc(Br)c2)nn1 +COc1ccc(C(O)CNc2ccccc2F)cc1N +Cc1cc(C)cc(C(=O)NCc2ccc(CN3CCCC3=O)cc2)c1 +CC(NC(=O)Cn1cnc(C2CCC2)cc1=O)c1ccc(Cl)cc1 +COc1cccc(OCC(=O)Nc2ccc3c(c2)OCCO3)c1 +Cc1nc(-c2ccc(C(=O)N3CCN(c4ccccc4)CC3)cc2)no1 +CC(=O)N1CCC(C(=O)Nc2c[nH]nc2C)CC1 +O=C(NCCNC(=O)c1cc2sccn2c1)c1ccccc1 +Cc1cc(C)n(CC(=O)Nc2c3c(nn2C)CCC3)n1 +COCCCC(=O)N1CCCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1cc(Cl)ccc1NC(=O)c1cc(N)cnc1C +COc1ccc(C(C)(C)C)cc1C(=O)CCC(=O)NC1CC1 +Cc1cccc(=O)n1CCC(=O)Nc1ccc(C#N)cc1 +CC(C)(NC(=O)CSc1ccncc1)c1cccc(F)c1 +Cc1cccc(-n2nnnc2SCCCCCO)c1 +CCC(C)NC(=O)Cn1c(C2CCOCC2)cc2cccnc21 +COC(=O)CCSc1nnnn1-c1cccc(C)c1 +COc1cccc(C(=O)Nc2cnn(-c3ccccc3F)c2)c1 +CCc1cc2c(=O)n(Cc3cc(F)cc4cccnc34)cnc2s1 +CCc1noc(CNc2ccc(S(=O)(=O)NC(C)C)cc2)n1 +CCCC(N)c1cc(Cl)ccc1S(C)(=O)=O +CCC(C)NS(=O)(=O)c1ccc(F)c(F)c1F +CC1CCCCC1N(C)C(=O)c1cn2cccnc2n1 +O=C(C1CC(=O)N(C2CCCC2)C1)N1CCN(c2nccs2)CC1 +CC(=O)Nc1ccc2oc(-c3ccc(C)cc3)cc(=O)c2c1 +Cc1cccc(NC(=O)c2cccc(C(=O)Nc3cccc(C)n3)n2)n1 +CC(C)C(NC(=O)c1ccc(F)cc1)C(=O)NCCc1ccccc1 +COC(=O)COc1cccc(NC(=O)c2cccc(OC)c2)c1 +CC(O)CN(C)c1cc(N)cc(S(N)(=O)=O)c1 +CCOc1ccc(NC(=O)c2cn[nH]n2)cc1F +Cc1noc(COC(=O)c2cc(C3CC3)nc3c2cnn3C(C)C)n1 +Cc1ccc(N2CCN(CC(=O)NCCO)C2=O)cc1 +COc1ccc(C(N)C(F)(F)F)cc1Br +CC(C)C(C(=O)N1CCOC(C)(C)C1)n1nnc(-c2ccccc2)n1 +CC(NC(=O)OC(C)(C)C)C(=O)NCCc1nnc2ccccn12 +Cc1ccccc1C(=O)NCCc1c[nH]c2ccccc12 +CCOC(=O)N1CCN(C(C)C(=O)NCCC(C)C)CC1 +CCNC(=O)CN(c1ccccc1F)S(=O)(=O)C(C)C +COC(=O)CCNC(=O)C1CC1c1ccccc1Br +O=C(c1cc(Cl)c[nH]1)N(CCO)C1CCCC1 +O=C(CNc1ncnc2[nH]cnc12)Nc1ccc(Br)cc1 +CCc1ccc(NC(=O)C23CCC(C)(C(=O)O2)C3(C)C)cc1 +COc1cc2c(c(Cl)c1O)C(c1nccs1)NCC2 +O=C(c1cc(-n2cccn2)ccn1)N1CCOc2ccc(F)cc21 +Cc1ccc(C)n1-c1c(C(=O)N(C)CCC(C)C)cnn1C +Cc1c(CNC(=O)NC(c2ccccn2)C2CCCC2)cnn1C +C=CCNC(=O)NC(C)(C(F)(F)F)C(F)(F)F +C=CCn1c(=O)nc2n1C(=O)N(c1ccc(F)cc1)C2 +c1ccc(CCNc2ncnc3c2oc2ccccc23)nc1 +COc1ccccc1OCC(C)CNc1ncnc2nn(C)cc12 +Cc1ccc(NC(=O)CN(C)C(=O)C(C)Sc2ccccn2)cc1 +Cc1ccccc1OCC(O)Cn1nc2c(cc1=O)CCC2 +O=C(CNC(=O)c1cc(F)cc(F)c1)Nc1ccc2ncccc2c1 +CCOC(CC)C(=O)NCc1nnc2n1CCCCC2 +Cc1nc(CCN2CCCC2=O)sc1C(=O)Nc1ccccc1 +O=C(NCCS(=O)(=O)N1CCCC1)Nc1ccc2c(c1)COC2 +COC(=O)CC1CCCCN1C(=O)Nc1ccc(C)cc1 +Cc1cccc(C(=O)N2CC3CCC2CN(C(=O)C2CCC2)C3)n1 +COc1ccc2c(c1)c(C(=O)NCC1CCOCC1)cn2C(C)C +Cc1cc(C)c2nc(C)cc(C(=O)N(C)Cc3nnc(C)o3)c2c1 +CCOc1ccc2ccccc2c1CNc1ccon1 +Cc1nc[nH]c1-c1nccn1Cc1ccccc1-n1ccnc1 +O=C(Nc1nc(-c2cccnc2)cs1)c1cc(Br)c[nH]1 +CC(=O)NCCNC(=O)NCCc1csc(C)n1 +COc1ccc(CNS(=O)(=O)c2ccccc2OC(F)F)cn1 +Cc1ccc(OCC(=O)N(C)CCC(F)(F)F)cc1C +O=C(Nc1ccc(-n2cc[nH]c2=O)cc1)c1ccc(NC2CC2)nc1 +O=C1CCc2cc(NC(=O)c3ccc(Cn4ccnc4)cc3)ccc2N1 +OCCCn1nnc(CO)c1-c1cccc(F)c1 +NC(=O)NCC(=O)NCc1cccnc1Oc1ccccc1F +CCCCS(=O)(=O)N(CCO)C1CCCCC1 +CCCCc1ccc(NC(=O)CSc2nnc(C)n2N)cc1 +CC(c1ccccc1)N(C)C(=O)c1cccc(NC(=O)NC2CC2)c1 +CCc1nc(CC(=O)N(CC)c2ccc(F)c(F)c2)cs1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2cccc(Cl)c2C)n1 +Cc1cccc2cc(COC(=O)COc3ccccc3)c(=O)[nH]c12 +Cc1cc(=O)c(C(=O)N2CCc3ccc(F)cc3C2C)c[nH]1 +Cc1nc(-c2ccccc2)sc1C(=O)N(CC(N)=O)C1CCCC1 +CN(C)c1ccc(C(=O)Nc2nnc(-c3cccs3)o2)cc1 +Cc1ccc(C(O)CNC(=O)c2cccc(Cl)c2)cc1 +O=C(NCC1CCCO1)c1cccc(N2CCCS2(=O)=O)c1 +CC(c1nc(-c2ccccc2)no1)N1CCOC(Cn2cccn2)C1 +O=C(Nc1ccccc1)Nc1ccn(CCc2ccncc2)n1 +O=C(CSc1cccc(C(F)(F)F)c1)N1CCCC1 +C1CCC(CCc2nc(C3CCOC3)no2)CC1 +Cn1c(SCC(=O)NC2CCCCCC2)nnc1-c1cccnc1 +N#Cc1ccc(OC2CCN(C(=O)CC3(O)CCCCC3)CC2)cc1 +O=C(CCCNC(=O)c1cccs1)Nc1nc2c(s1)CCCC2 +CC(=O)N1CCN(C(=O)C(C)n2nc(C)ccc2=O)CC1 +CC(C)c1nc2ccc(NC(=O)NC3CCCNC3=O)cc2s1 +Cc1c(Cl)cccc1NC(=O)C(C)c1nc(CO)cs1 +Cc1[nH]ncc1C(=O)N1CCN(CC(=O)NC2CCC(C)CC2)CC1 +Cc1cc(C)nc(NC(=O)C(C)Oc2ccc3c(c2)OCO3)n1 +CNC(=O)Nc1ccc(NC(=O)c2ccccc2)cc1C(F)(F)F +CC(Nc1ccc(NC(=O)c2ccc(=O)n(C)c2)cc1)c1ccccc1 +O=C(Nc1ccc2ccccc2n1)C1CC(=O)N(C2CCCC2)C1 +COC(CNC(=O)COc1ccccc1)c1ccc(C)s1 +Cc1ccc(F)cc1NC(=O)Cc1ccc2c(c1)OCCO2 +O=C(NCc1cccnc1)C1CC(=O)N(c2ccc(Cl)c(F)c2)C1 +Cc1ccccc1C(CC(=O)N(C)Cc1cnn(C)c1)NC(N)=O +CCOc1ccccc1NS(=O)(=O)c1ccc2c(c1)CC(=O)N2 +COC1CCC(CC(=O)Nc2[nH]nc(-c3ccc(C)o3)c2C)CC1 +Cc1cc(NC(=O)C2COc3ccc(F)cc3C2)no1 +OCCc1cc(CC2(NCc3cccs3)COC2)no1 +CCn1c(-c2cc(OC)cc(OC)c2)nc2c(N)cccc21 +Cn1ccnc1S(=O)(=O)CC(=O)NCc1ccccc1 +CC(C#N)CN(C)C(=O)COc1ccc(Cl)cc1Br +CC(=O)OCC1OC(n2cnc(C(N)=O)n2)C(O)C1O +C#CCN(Cc1ccccc1Cl)C(=O)C(C)NC(N)=O +Cc1nc(NC(=O)C(C)Sc2ncc3ccccn23)sc1C +Cc1cccc2[nH]c3c(N4CCOCC4)ncnc3c12 +Cc1cccc(C)c1NC(=O)COc1ccc(C(N)=O)cc1 +CS(=O)c1ccc(CNc2ccc(C(F)(F)F)c(C#N)c2)cc1 +O=C(NCc1ccco1)c1cc2ccccc2oc1=O +Cc1cc(C(=O)NCc2ccoc2)c2c(C)noc2n1 +COc1ccc(NC(=O)CC(O)(c2nccn2C)C(F)(F)F)cn1 +Cc1occc1COC(=O)c1ccc(CNC(N)=O)cc1 +O=C(Nc1cnn(C2CCOC2)c1)c1c[nH]c(=O)c(Cl)c1 +O=C(Nc1ccn(Cc2cccnc2)n1)C1CC2C=CC1C2 +CCc1onc(C)c1NC(=O)N1CCC(CC(C)C)C1 +COc1ccnc(NC(=O)c2cccc(-n3cncn3)c2)c1 +CCCS(=O)(=O)N1CCN(C(C)C(N)=O)CC1 +COC(=O)Cc1csc(COc2ccccc2C)n1 +NC(=O)Nc1ccc(CNC(=O)c2ccc(F)cc2F)cc1 +COC(=O)c1ccc(N2CCN(C(=O)C(C)C)C(C)C2)cc1 +CC(C)CN(CC(C)C)S(=O)(=O)c1ccc2c(c1)C(=O)NCC2 +CCOC(=O)N1CCN(C(=O)C2(c3ccccc3)CCOCC2)CC1 +CCOC(=O)C1CCCN1C(=O)C(C)n1cccn1 +Cc1cc(NCCn2cnnc2C(C)C)nc(-c2ccncc2)n1 +CC(=O)Nc1cc(NC(=O)c2cnc(C3CCCO3)s2)ccc1C +O=C(c1csc(S(=O)(=O)NC2CCCC2)c1)N1CCCCC1 +Cn1cccc1C1CCCCCN1C(=O)c1cccc(F)c1 +Cc1cc(C)c2c(CC(=O)NCCN3CCOCC3)coc2c1 +COC(=O)c1cc(C(=O)OC)cc(-n2nnc(C#N)c2C)c1 +CCn1c(C)cc(C(=O)NCc2nc(-c3ccncc3)cs2)c1C +CC(NC1=NS(=O)(=O)c2ccccc21)C(=O)OCC(F)(F)F +CSc1ccc(OCCNS(=O)(=O)c2cccs2)cc1 +COc1cc(-c2n[nH]c(=O)n2-c2ccc(F)cc2F)ccc1O +COc1cc(N)ccc1C1CCCN1S(C)(=O)=O +Fc1ccc(F)c(N2CCN(Cc3cc[nH]n3)CC2)c1 +CC(=O)NC(C)C(=O)NCCc1ccc(Cl)cc1 +c1ccn2c(CCNCc3ccc(-n4ccnc4)cc3)nnc2c1 +CCc1ccc(C(O)CNC(=O)c2cccc(F)c2)cc1 +CC(C)c1cc(C(=O)N(C)CCc2ccccn2)n[nH]1 +CN1C(=O)Cc2cc(S(=O)(=O)N(C)C)cc(N)c21 +CCS(=O)(=O)N1CCOC2(CCCC2COc2cccnc2)C1 +CCC(CC)N(CCO)C(=O)c1cc(N)cn1C +CC(C)NC(=O)c1ccc(Cn2cnc3ccccc3c2=O)o1 +O=C1NC(c2csc(C3CC3)n2)Nc2ccccc21 +Cc1ccc(C(=O)NC2CCCS(=O)(=O)c3ccccc32)o1 +O=C(Cn1ccnc1)NC(c1ccccc1)c1ccc(Cl)cc1 +COc1cccc(CNc2cc(N3CCCC3CO)ncn2)n1 +CCc1cn[nH]c1C1CCN(c2nc(C)ccc2C#N)CC1 +CC(Cc1cccs1)NS(=O)(=O)c1ccc2c(c1)CCC2 +Fc1ccc(C(CNCc2ccncc2)N2CCCC2)cc1 +Cn1cc(CCCCNC(=O)Cc2c[nH]c3ccc(Cl)cc23)cn1 +Cc1ccc(OCC(=O)NCCNC(=O)c2ccco2)cc1C +Cc1cc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)on1 +Cc1ccc(OCC(=O)Nc2ccc(N)nc2)cc1 +Cc1cccc(S(=O)(=O)N(C)c2ccc(O)cc2)c1 +O=C(Cc1noc2ccccc12)Nc1ccccc1-c1ccc(=O)[nH]n1 +Cc1ccc(NC(=O)N2CCCC(C)C2CO)cc1C(=O)NC(C)C +COc1ccc(CN(C)S(=O)(=O)Cc2cccc(F)c2)cc1C +CCOC(=O)C(O)Cc1cc(C(F)(F)F)ccc1F +Cn1c(=O)c2ccn(CC(=O)NCc3ccco3)c2n(C)c1=O +CC(=O)Nc1ccc(SCC(=O)NCc2cccs2)cc1 +CCOC(=O)C(N)c1c(F)cccc1C(F)(F)F +CCN(C(=O)C(C)S(=O)(=O)c1ccc(O)cc1)c1ccccc1 +CCNC(=O)N1CCNC(=O)C1CC(=O)Nc1ccccc1OCC +COc1cc(=O)n(CC(=O)NCC2CCCO2)nc1-c1ccccc1 +COc1ccc(SCC(=O)N2CCCC2)cc1 +Cc1ccc(NC(=O)Nc2ccc3c(c2)CCC3)nc1 +CCc1cc(C(=O)NCCc2cc(F)cc3c2OCOC3)[nH]n1 +COc1ccc(C)cc1NC(=O)CSc1nc(=O)ccn1C(C)C +CC(C)(C)c1noc(OCc2cn3ccccc3n2)n1 +N#Cc1cn(C2CC2)c(=O)n(CC(=O)N2CCCCC2)c1=O +O=C(Nc1cc(F)c(F)cc1Cl)c1ncn(-c2ccccc2)n1 +COC(=O)Cn1c(-c2cccc(N)c2)nc2cc(O)ccc21 +Cc1cnc2c(c1)ncn2CCOc1ccc(N)c(C)c1 +CCN(C(=O)CCNC(=O)c1ccccc1)C1CCCCC1 +Cc1ccc(OCCCSc2nnc(C)c(=O)n2N)cc1C +Cc1nn(C)c(C)c1NC(=O)CSc1nnnn1C(C)(C)C +CCc1cnccc1C(=O)N1CCC(C(N)=O)c2ccccc21 +CCCNC(=O)Cc1cn2cc(Br)ccc2n1 +CCc1noc(-c2ccc(C)c(NC(=O)NCc3ncnn3C)c2)n1 +CC(NC(=O)Nc1cccc(Cl)c1F)C(=O)N1CCCCC1 +O=C(CSc1ccncc1)NCC1CCCc2ccccc21 +Cc1cc(Cl)ccc1NCCC(O)c1cccc(N)c1 +CC(CC(=O)Nc1ccccn1)NC(=O)c1ccccc1 +CCC1CCCN(C(=O)Nc2ccc(OC)c(NC(C)=O)c2)C1 +CC(NC1=NS(=O)(=O)c2ccccc21)c1ccc2c(c1)OCO2 +O=C(Nc1nncs1)NC(CO)c1ccccc1 +CCc1ccc(OCCCN2C(=O)COc3ccc(N)cc32)cc1 +Cc1cc(Br)ccc1NCC1CCCO1 +Cc1cc(=O)[nH]c2cc(NC(=O)Cc3noc4ccccc34)ccc12 +CCCN(Cc1ccsc1)S(=O)(=O)C1CC1 +Cc1cc2ccccc2n1CCCNC(=O)c1ccc(=O)[nH]c1 +CN(C)S(=O)(=O)N1CCCC1CS(=O)(=O)c1ccccc1 +CCn1cnnc1CNC(=O)c1cnn(-c2ccccc2)c1C +CCc1nc(CNc2ccc(N3CCCC3=O)c(OC)c2)cs1 +CC(=O)Nc1ccc(NS(=O)(=O)c2ccccc2)cc1 +O=C1CCCN1CC1CCN(C(=O)c2c[nH]c(=O)c(Cl)c2)CC1 +COC(=O)c1cccc(NC(=O)c2cccc(OC(C)=O)c2)c1 +COc1ccc(-c2cc(CO)c(=O)n(CCC(C)C)n2)cc1 +N#Cc1c(F)cccc1NCCNC(=O)NCc1ccccc1 +O=C1CCCCCN1CCc1nc(Cc2ccccc2)n[nH]1 +CCCNC(=O)CCNC(=O)Nc1ccc(F)c(F)c1 +Cc1ccccc1CN(C)C(=O)COc1ccc(C(N)=O)cc1 +O=C1CC2(CCN(C(=O)C3CCC3)C2)Oc2ccccc21 +CSc1ccc(Cl)c(C(=O)NCCC(O)C(C)(C)C)c1 +NC(=O)COC(=O)c1cnn(-c2ccc(Cl)cc2)c1C(F)(F)F +O=C(Nc1cccnc1)N1CCCC2(CC=CCC2)C1 +CC(C)(C)C(NC(=O)c1ccc2nncn2c1)C(F)(F)F +COc1cc(COC2CCCN(C(=O)CC(C)C)C2)cc(OC)c1 +CC(C)(C)C(=O)N(Cc1ccsc1)Cc1ccco1 +CCc1ccc(NC(=O)CSc2nnc(CC)n2C)cc1 +CC(=O)Nc1cccc(NC(=O)C(O)c2ccc(F)cc2)c1 +CC(C)CNS(=O)(=O)c1ccc(CNC(=O)C2CCC2)cc1 +COCc1ccc(C(=O)N2CCCC(CO)(CC3CC3)C2)o1 +Cn1nc(C(=O)N2CCCCCC2)c2c1-c1ccsc1CC2 +CCCC(C(=O)N1CCN(CC2COCCO2)CC1)c1ccccc1 +O=C(NCC1CC=CCC1)C1Cc2ccccc2O1 +Cc1cccc(NC(=O)c2ccc(C)c(NC(=O)NC(C)(C)C)c2)n1 +CS(=O)(=O)N1CCC(Nc2ccc3nnnn3n2)CC1 +Cc1noc(C)c1C(=O)Nc1cccc(-n2cccc2)c1 +CN(CC(=O)Nc1nccs1)S(=O)(=O)c1ccccc1 +CCOc1ccccc1C(=O)Nc1cccc(NS(C)(=O)=O)c1 +CC1COCCN1CC(C)(C)C(N)c1ccccc1 +CC(=O)Nc1ccc2nc(-c3cn(Cc4ccccn4)nn3)ccc2c1 +Cc1nnc(SCCCc2ccc(Cl)cc2)n(N)c1=O +COc1c(-c2ccccc2)oc2ccc(O)cc2c1=O +O=C(Nc1nccs1)C1CCN(C(=O)c2ccccc2Cl)CC1 +Cc1cnc(C(NC(=O)C2CC2c2ccccc2)C2CC2)s1 +CCc1nc(CN(C)C(=O)c2cc3c(s2)CCC(C)C3)no1 +COCC(NC(=O)NCCc1ccc(F)cc1C)c1ccco1 +Cc1ccc(NC(=O)CN(C)C(=O)CNC(=O)c2ccccc2)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)NC1CC1C +CC(c1cccnc1)N1C(=O)c2ccccc2S1(=O)=O +Cc1csc(N2CCN(c3ncnc4cccc(F)c34)CC2)n1 +Cc1ccccc1SC(C(=O)N(C)C)c1ccccc1 +CCCNC(=O)C1CCN(C(=O)c2cccc(Cl)c2)CC1 +COc1cccc(CCNC(=O)CCn2ncc3ccccc32)c1 +COC(=O)c1ccccc1NC(=O)NCc1ccco1 +CC(C)Oc1cccc(CNC(=O)NCCC(=O)N2CCCCC2)c1 +O=C(OC1CCOC1=O)C1CCCC(C(=O)OC2CCOC2=O)C1 +COC(=O)c1ccc(NC(=O)c2n[nH]c3ccccc23)cc1 +CCCn1nc(-c2ccccc2Cl)cc(C(C)=O)c1=O +NC(=O)N1CCCC(C(=O)NC2CCCCC2)C1 +Cc1nc(N2CC3CC(C2)c2cccc(=O)n2C3)c2sccc2n1 +CCN(c1nc(C)c(C(C)=O)s1)C1CCCC1 +CCOc1ccc(OC)cc1NC(=O)c1c[nH]c2ncccc12 +Cc1cc(C)cc(C(=O)NCC(=O)N(C)Cc2ccsc2)c1 +CCc1nc(CN2CCN(C(=O)Cn3cnnn3)CC2)cs1 +CC(C)Oc1cc(NC2c3ccccc3CC2O)nc(N)n1 +CCN(c1ccccc1)S(=O)(=O)c1cc2c(cc1C)NC(=O)CO2 +CCOC(=O)CSc1nnc(-c2ccccc2)o1 +CN(Cc1ccccc1-n1cccn1)C(=O)c1ccc2ccn(C)c2c1 +CC1CCc2c(C(=O)N(C)Cc3cnn(C)c3)csc2C1 +Cc1n[nH]c(-c2cccc(CNC(=O)CNC(=O)C(C)(C)C)c2)n1 +Cc1ccc(-c2ncco2)cc1NC(=O)NCC(=O)N1CCCC1 +CC(=O)Nc1ccc(NC(=O)c2cccc(NC(N)=O)c2)cc1 +CC(C)c1nnc(NC(=O)Cc2cccs2)s1 +CC(C)N(C)C(=O)NC1CCN(c2ccc(C(F)(F)F)cn2)CC1 +Clc1ccccc1OCc1nncn1-c1cccnc1 +O=C(NCCc1cccs1)c1cn(-c2ccccc2)nn1 +Cc1nc(C)c(C(=O)NCCc2ccccc2)s1 +COc1ccccc1N1CCN(c2cccc(N)c2)CC1 +COCC(=O)Nc1cc(OC)c(Br)cn1 +N#CCCCn1nc(C#N)cc1-c1cccc(Cl)c1 +Cc1cc(C)n(CC(=O)N(c2ccc(S(C)(=O)=O)cc2)C(C)C)n1 +O=C(NC1CCCC1)N(Cc1cccnc1)C1CC1 +Oc1ccc(O)c(Cc2nc3ccccc3s2)c1 +CC(OC(=O)c1ccc(Cl)c(N)c1)C(=O)Nc1ccccc1 +O=C(Nc1cccc(F)c1)C(O)c1ccc(F)cc1 +CCC1N(C(=O)c2ccoc2)CCCC12CCC(=O)N2 +O=C(CSc1nc2ccccc2c(=O)[nH]1)Nc1ccccc1 +CCN(C)c1ccc(C(=O)NCCC(=O)N(C)C)cc1 +Cc1ccc2[nH]nc(C(=O)NCCc3cnn(C)c3)c2c1 +COC(=O)c1ccc(Nc2oc(C)cc(=O)c2C(C)=O)cc1 +O=C(NCc1ccsc1)c1ccccc1Br +O=C(c1cc2ccccc2[nH]c1=O)N1CCCC1Cn1cccn1 +Cc1ccccc1C(=O)N1CCCC(c2nnc3ccccn23)C1 +C=CC1OC(OC)C(O)C1OCc1ccc(OC)cc1 +CC(NC(N)=O)C(=O)N(Cc1ccc(Cl)c(Cl)c1)C(C)C +C=C(C)COCCNC(=O)Nc1c(C)noc1CC +COCCN1CCN(C(=O)Cc2cccc(O)c2)CC1=O +Cc1n[nH]c(C)c1S(=O)(=O)N1CCNC(=O)C1 +COc1cc(N)c2ccnc(C(=O)Nc3ccccc3)c2c1OC +COc1ccc(OCn2ccc(C(=O)Nc3cc(C)on3)n2)cc1 +CCCc1nc(N2CCCCCC2)sc1CO +CN1CCOC(CNS(=O)(=O)C2CN(C(=O)C3CCCC3)C2)C1 +CCS(=O)(=O)N1CCN(C(=O)Nc2ccccc2SC)CC1 +CCSc1ccc(CC(=O)NCCCO)cc1 +CCOC(=O)c1csc(NC(=O)C(C)Oc2cccc(C)c2)n1 +COc1ccccc1C(O)c1ccc2[nH]c(=O)[nH]c2c1 +CCC(CC)N(CCO)C(=O)c1cc(C)sc1C +COc1cccc(C(=O)CCN2CCC(=O)CC2)c1 +CN(c1ccccn1)S(=O)(=O)c1ccc2c(c1)CCC2 +C=CCC(NC(=O)OC(C)(C)C)c1ccc(OC)cc1 +Cc1sc(C(N)=O)cc1NC(=O)c1cccc(-n2ccnn2)c1 +Cc1ccc(=O)n(C(C)C(=O)NCc2ccccn2)n1 +CC(C)C1CCC(=O)CC1n1nnc2ccccc21 +CCCOC(=O)C(C)N1C(=O)C(CC)Oc2cccc(N)c21 +Cc1ccc(C(C)NC(=O)Cn2cnc(-c3nc(C)cs3)c2)cc1 +Cc1cccc(C(C)C)c1NC(=O)c1cscn1 +COC(=O)CNC(=O)c1cc(OC)ccc1Br +CN(Cc1ccccc1)Cc1nc2sc3c(c2c(=O)[nH]1)CCC3 +C=CCN(CC(F)(F)F)C(=O)Nc1ccc(C#N)cc1 +Cc1cc(C)cc(N2CCC(C(=O)N3CCCC(C)C3)C2=O)c1 +CNC(=O)COC(=O)c1oc2ccccc2c1COc1ccccc1 +CC(C)C(=O)Nc1ncc2c(n1)CC(c1cccs1)CC2=O +CCCn1c(SCCC#N)nc2cc(Cl)ccc2c1=O +COc1ccc(OC)c(CC(=O)NCCC(C)C)c1 +COCC(=O)Nc1cccc(NCc2ccc(S(C)=O)cc2)c1 +CCC(CC)N1CC(C(=O)Nc2nnc(C(C)(C)C)s2)CC1=O +c1cnc2ccc(OCCc3nc4c(s3)CCCN4)cc2c1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2ccccc2)cc1 +O=C(C1CCOC1)N1CCCN(c2ccccc2)CC1 +O=C(CCCn1cncn1)N1CCCC(c2nc3ccccc3[nH]2)C1 +CC(=O)Nc1ccccc1C(=O)Nc1c(Cl)cccc1Cl +Fc1cccc(CCNc2ncnc3[nH]cnc23)c1 +CC(C)(Br)C1OCc2ccccc2CO1 +COCCN(CCC#N)C(=O)Nc1ccc2c(c1)Cc1ccccc1-2 +O=C(Cc1ccc2c(c1)OCCO2)Nc1nnc(C2CC2)s1 +OCc1nnn(Cc2ccc(F)cc2)c1C1CCC1 +O=C(CSc1nnnn1-c1cccc(F)c1)C1=NC=CC1 +Cn1cc(C(=O)NCc2cc(=O)n3c(n2)CNCCC3)cn1 +CC1(C(=O)Nc2ccc(CN3CCOCC3)cc2)CC1(Cl)Cl +COCC(C)Nc1ncnc(Sc2cccc3cccnc23)c1N +COC(=O)c1ccc(C(=O)Nc2nnc(-c3ccccc3)o2)cc1 +O=C(CCCOc1ccccc1F)NCc1cc[nH]c(=O)c1 +O=C(NCC#CCOc1cccnc1)c1ccc(-n2cccc2)cc1 +O=C(CCc1ccccc1F)N1CCC(C(=O)N2CCCCCC2)C1 +COc1ccc(CNC(=O)c2cc(-c3ccccc3)no2)cc1 +Cc1nc2c(Nc3cccc(C#N)c3)ncnc2[nH]1 +CCCCC(=O)Nc1ccccc1S(=O)(=O)N1CCCCC1 +CCN(CC)C(=O)c1cccc(NC(=O)c2ccco2)c1 +COc1cc(F)c(S(=O)(=O)NC2CCCCNC2=O)cc1OC +CC(=O)Nc1ccc(F)c(NC(=O)NC2C3CCC(C3)C2CO)c1 +CC(C)NC(=O)Cn1c2ccccc2c2cn[nH]c(=O)c21 +O=C(NCC1(c2ccc(Br)cc2)CCOCC1)C1CC1 +CN(C)c1nc(N)nc(CNc2nccc(CCC(F)(F)F)n2)n1 +O=S(=O)(Cc1ccc(Cl)cc1)N1CCCC1 +CCn1ccc(C(=O)Nc2nnc(-c3ccnn3C(C)C)o2)n1 +COC(=O)N1CCC(NC(=O)Nc2cc(-c3ccccc3)on2)CC1 +Fc1ccc(-c2noc(CN3CCOC4CCCCC43)n2)cc1 +CC1CN(C(=O)c2cc(-c3cccnc3)nc3ccccc23)CC(C)O1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)OCCCc1cccnc1 +CCOC(=O)Cn1c(C)c(C(=O)OC)c2cc(O)ccc21 +CCOc1ccc(COC(=O)c2cc(C)oc2C)cc1OC +c1coc(-c2nnc(SCCN3CCOCC3)o2)c1 +O=S(=O)(c1ccccc1)N(CCc1cccs1)Cc1ccoc1 +Cn1nc(C2CCN(C(=O)NC(C)(C)C)CC2)n(C2CC2)c1=O +CCC1CCC(NC(=O)N2CCN(C(=O)N(C)C)CC2)CC1 +O=C1NCCOC2CN(C(=O)Cc3cccc(F)c3)CCC12 +CCOC(=O)Cn1cnc2c(nnn2Cc2ccccc2F)c1=O +CN(CCCc1cc(-c2ccccc2)no1)C(=O)CC1CCCO1 +Cc1ccc(C#N)cc1NC(=O)C(C)NS(C)(=O)=O +O=C(NCCCc1ccccc1)c1cc(F)cc2[nH]cnc12 +Cc1ccc(C2CCCN2S(=O)(=O)c2cnn(C(C)C)c2)o1 +Oc1ccc2c(c1)NCC(Cc1ccc(F)cc1)O2 +CC1(C)CC(=O)c2c(N)nc(NCc3ccccc3)nc2C1 +COCCN(Cc1ccccn1)C(=O)c1cnc(N(C)C)nc1C +CNC(=O)C1CCCN(C(=O)NCCCC(C)(C)CO)C1 +Cc1nc(N(C)C)sc1CN1CCNC(=O)CC1 +COC(=O)C1CN(c2ccc(Cl)cc2C)CCC1=O +CCn1nnc2c(SCc3ccccc3)ncnc21 +CC(Cn1nc(-c2cccs2)oc1=O)NC(=O)c1cccs1 +Cc1nc(SC2CC(C)OC2=O)c2ccccc2n1 +CCC(=O)N1CCCC(C(=O)NCc2cc(C)oc2C)C1 +O=C(CCc1cccnc1)NCC12CC3CC(CC(C3)C1)C2 +O=C(NCCc1nccn1Cc1ccccc1)Nc1cccc(F)c1 +CCc1onc(C)c1NC(=O)N(C)CCOCC1CC1 +CCc1onc(C)c1NC(=O)C(NC(C)=O)C1CCCC1 +CCN(C(=O)COc1ccc(Cl)c(Cl)c1)C1CC1 +NC(=O)CSc1nnnn1-c1ccccc1Cl +COc1ccccc1C(C)NC(=O)c1c(F)cccc1F +COCC(O)COc1ccccc1C(=O)N1CCOCC1 +CS(=O)(=O)NCCNC(=O)Cc1ccc(F)cc1 +Cc1nn(CCO)c(C)c1CN1C(C)COC(c2ccccc2)C1C +CC(NC(=O)COCC(F)(F)F)c1ccc2c(c1)CCC(=O)N2 +CS(=O)(=O)c1ccccc1C(=O)OCc1cccc(F)c1F +CC(C)C(Sc1ncn[nH]1)C(=O)N(C)c1ccccc1 +CC(C)(C)C(=O)N1CCCC(C(=O)NCCOc2cccnc2)C1 +Cc1cccc(C(C)C)c1NC(=O)NCC(=O)NC(C)(C)C +CCCCNC(=O)Cn1c(C(C)C)nc2c(N)cccc21 +CC(NC(=O)C1CC1)c1nc2ccccc2n1C(C)C +CCN(CCC(=O)OC)C(=O)c1ccc(O)c(Cl)c1 +CC(C)Cc1ncc(CNc2cnn(-c3ccccc3)c2)s1 +Nc1nc(NCCCc2nnc3ccccn23)cc(N2CCCC2)n1 +Cc1ccncc1NC(=O)N1CCC(OCC(C)C)C1 +CNC(=O)c1cc(Cl)ccc1NC(=O)c1ccc(OC)nn1 +CCCNC(=O)CSc1nnc(-c2ccccc2)n1CC +O=C1c2ccccc2S(=O)(=O)N1CCn1nnc2ccccc21 +COCc1ccc(C(=O)Nc2ccc(C(C)=O)c(C)c2)o1 +CNC(=O)C(C)NC(=O)c1cc2sc(N(C)C)nc2s1 +CCS(=O)(=O)c1ccc(NC(=O)NC(C)c2ccc(C)o2)cc1 +Cc1ncc(C(=O)NCc2ccccc2OCc2ccccc2)cn1 +Cc1ccc(C(=O)N2CCOC(c3cccc(O)c3)C2)s1 +CCC1Oc2cc(CO)ccc2N(C(C)C(=O)OC)C1=O +CC(NC(=O)c1ccccc1)C(=O)N(C)CCC#N +COC(=O)Cc1ccc(-n2ncc3c2CCNC3)cc1 +CC(NC(=O)c1ccco1)c1nc2ccccc2n1C(=O)c1ccco1 +CCCc1cc(C(=O)OCCc2cccnc2)[nH]n1 +CC(NC(=O)NC1CCCC1)C(=O)N1CCCCC1 +O=C(c1ccccc1C(F)(F)F)N1CC(c2nc3ccccc3[nH]2)C1 +O=C(c1cccc(-n2cccc2)c1)N1CCCC1Cn1cccn1 +Cc1nc(C)nc(CCc2ccccc2Br)n1 +Cc1cc(C(=O)NCC2CCCO2)cc(S(=O)(=O)N(C)C)c1C +CCCOc1cc(C2NC(=O)c3ccccc3N2)ccc1OCC +COC(=O)c1ccc(C)c(C(=O)NC2CCCC2)c1 +Cc1nnc(NC(=O)CN2C(=O)CCOc3ccccc32)s1 +COc1cc(CC(=O)NC2CCN(C(=O)CC(C)C)CC2)ccc1C +CC(NC(=O)Nc1ccnn1C(C)C)c1ccc(Cl)cc1 +CC(C)(C)N1CC(C(=O)N2CCC(Cc3ccccc3)CC2)CC1=O +Cc1noc(CCCC(=O)NC(C)c2ccc(-n3ccnn3)cc2)n1 +CCCn1cc(C(=O)N2CCC(n3cccc3)CC2)c2ccccc21 +O=C(NCC1CCCO1)c1cc(-c2cccnc2)n(-c2ccccc2)n1 +COc1cc(C(=O)N2CCOCC2)cc(Cl)c1OCC(N)=O +O=C(NCC(F)(F)F)c1cc(F)ccc1C#CCO +CNC(=O)c1ccc(NC(=O)c2ccc(C)o2)cc1 +CSc1nsc(NC(=O)c2ncoc2C(C)C)n1 +Cc1n[nH]c(C)c1NC(=O)Nc1ccc(-c2nnnn2C2CC2)cc1 +O=c1onc(-c2cccnc2)n1Cc1ncc(-c2cccs2)o1 +CCOc1cc(C)c(C)cc1C(=O)CN1CC(C)OC(C)C1 +Cc1cccc(-c2nnc(C(C)N3CCc4c(nnn4C)C3)o2)c1 +COc1ccc(NC(=O)NCCCc2cn[nH]c2C)cc1 +COC(=O)c1ccc(CCNC(=O)c2ccc3c(c2)OCO3)cc1 +CCn1cc(C(=O)NCC2CCCO2)c(=O)c2ccc(Cl)c(C)c21 +Cc1nccn1-c1ncccc1NC1CCCCC1 +CCCn1ncc(C(=O)N2CCC(Cc3cccc(CO)c3)C2)c1C +COC(=O)c1cc(CN(C)C(=O)C(C)CC2CCCC2)oc1C +COc1cccc(NC(=O)c2cnc(N3CCCC3)nc2)c1 +Cc1nccnc1OCCCC1CCCN(C(=O)OC(C)(C)C)C1 +COC(=O)N1CCC(CNS(=O)(=O)c2ccc(F)c(C)c2)CC1 +N#Cc1ccc(N2CCCN(CCn3cccn3)CC2)cc1 +Nc1ccc2c(c1)nc(C1CC1)n2Cc1ccc(N)nc1 +CCN(Cc1cccs1)S(=O)(=O)c1ccc(F)cc1 +O=C(Cc1cccc2ccccc12)NCC(=O)N1CCCCCC1 +CCCC1NC(=O)C2CC(NC(=O)c3ccc(Cl)cc3)CN2C1=O +Cc1ccccc1NCC(O)COc1ccc2c(c1)OCO2 +CC(O)COc1nc(N)nc2c1ncn2C1CC(O)C(CO)O1 +O=C(NCC1CN2CCCCC2CO1)c1cccc(C(F)(F)F)c1 +CCOCC(=O)N1CCCC2(CCC(=O)N(CCC(C)C)C2)C1 +Cc1nnc2sc(Cc3cccc4ccccc34)nn12 +NC(=O)c1n[nH]c2ccc(NCC3CC4C=CC3C4)cc12 +CNC(=O)CN1C(=O)C(C)(C)Oc2cc(O)ccc21 +CCC(=O)N1CCCCC1C(=O)N=c1[nH]c2ccccc2n1CC +C#CCN1CCN(C(=O)CNc2ccc(Cl)cc2Cl)CC1 +COCCCn1ccc(NC(=O)N(C)Cc2ccccc2)n1 +Cc1ccc(C)c(C(N)C(=O)NCC(O)CO)c1 +CCN1CCN(C2CCN(C3CCOC3=O)CC2)C1=O +C1=C(CN2CCOCC2C2CC2)COc2ccccc21 +COC(=O)c1ccc(NC(=O)CNC(=O)C2CCCCC2)cc1 +CN(C(=O)c1cc[nH]n1)C1CCN(C(=O)OC(C)(C)C)CC1 +CC(C)CCNC(=O)C1CCN(C(=O)C(C)(C)C)CC1 +Cc1cnc(C(=O)Nc2ccc(Sc3nncn3C)cc2)cn1 +O=C(NCc1ccccc1)NCc1ccc(NC(=O)C2CC2)cc1 +OC1CCN(c2ccnc(-c3cc(F)cc4cccnc34)n2)C1 +Cc1ccc(Cl)cc1S(=O)(=O)N(CC(N)=O)C1CCCC1 +CCc1nc(CC(=O)Nc2ccc(C)c(S(N)(=O)=O)c2)cs1 +Nc1c(Nc2cc(F)ccc2F)ncnc1-n1cnc2ccccc21 +CS(=O)(=O)N1CCN(CCNC(=O)c2ccco2)CC1 +CC1CCN(C(=O)c2ccc(S(=O)C(C)C)cc2)CC1 +COC(=O)c1sccc1S(=O)(=O)N(C)Cc1cccs1 +COc1cccc(Cc2nnc(SCCCO)o2)c1 +Cc1ccc(Br)cc1NC(=O)CNC(=O)c1ccoc1 +Cc1ccc(C)c(OC(=O)CSc2nnnn2C2CC2)c1 +CC(C)C(C)NC(=O)c1ccnc(-n2cncn2)c1 +CCOC1CC2CN(C(=O)c3cnoc3C)CCN2C1 +Cc1occc1-c1nnc(SCc2noc(-c3ccccc3)n2)o1 +CS(=O)(=O)N1CCCCC1C(=O)NCc1cccc2ccccc12 +CC(C)COc1cccc(C(=O)N2CCN(CCC#N)CC2)c1 +Cn1nnnc1SCCNC(=O)c1ccc2cccc(F)c2n1 +FC(F)(F)C(NCCN1CCOCC1)C1CCCC1 +Cc1noc(COC(=O)c2ccn(-c3ccc(F)cc3)n2)n1 +CN(CCC#N)C(=O)Cc1ccc(NC(=O)OC(C)(C)C)cc1 +CC(COc1cccc(F)c1)NC(=O)c1cccc2c1OCC(=O)N2 +C#CCNC(=O)c1ccc(Br)cc1Cl +CCOc1ccc(S(=O)(=O)N2CC(C)OC(C)C2)cc1 +COc1ccc(OC)c(C(O)c2ccccc2F)c1 +O=C(NCCn1ccnc1-c1ncccn1)Nc1ccc(F)cc1 +CC(C)(C#N)NC(=O)Cc1ccc(OC(F)(F)F)cc1 +O=C(NCCC(=O)OCC(F)(F)F)NC12CC3CC(CC(C3)C1)C2 +COc1ccc(Cc2noc(-c3ccc[nH]3)n2)cc1OC +CCCCNC(=O)CCn1ncc2cccc(C)c21 +Cc1noc(C)c1S(=O)(=O)N(Cc1ccccc1)Cc1ccco1 +CCc1cccc(OC(=O)CN(C)C(=O)c2cccs2)c1 +CCSc1cccc(C(=O)Nc2ccc(S(C)(=O)=O)cc2)c1 +Cn1cc(Br)cc(NC(=O)CC2CCC2)c1=O +CC(C)CCN1CC2CCN(C(=O)C3CCC3)CCC2S1(=O)=O +CCC(=O)Nc1cc(C(=O)OC)ccc1C(=O)OC +CN(C)c1cc(F)c(C(=O)NC(C)(C)C)cc1F +COCC(C)NC(=O)N(C)C(C)c1ccc(S(N)(=O)=O)cc1 +Nc1ccc(C(=O)N2CCN(C(=O)c3ccc(N)cc3)CC2)cc1 +CCCS(=O)(=O)N(CCC#N)Cc1ccccn1 +COc1cn(-c2ccc(F)cc2)nc1C(=O)Nc1nc(C)cs1 +O=C(CCC(=O)NC12CC3CC(CC(C3)C1)C2)NCc1ccco1 +CCOc1ccccc1-c1cc(C)nc2[nH]nc(N)c12 +Cc1nc(N(C)C)ncc1C(=O)NC(C)CCc1ccc(F)cc1 +COc1cc(-c2nc(C)c(C)s2)cc(OC)c1OC +Cc1nn(C)c(=O)c(C(=O)Nc2ccc3ncccc3c2)c1C +COCCN1C(C)CN(C(=O)Nc2cnccc2C)CC1C +O=C1NCCCc2[nH]c(-c3cnc4ccccn34)nc21 +COc1ccc(Nc2cc(C(F)(F)F)cnc2N)cc1 +O=C(CNC(=O)c1cccs1)Nc1ccc(Cl)c(Cl)c1 +O=C(NCCCN1CCOCC1)c1cc2ccccc2cc1O +NC(=O)CCCNC(=O)c1cc2c(nc3sccn32)s1 +Cc1ccc(-n2c(=O)[nH]c3c(sc4nc(C)cc(C)c43)c2=O)cc1 +CC(C)N(C)C(=O)Cn1cc(C(F)(F)F)ccc1=O +Cc1c(Cl)cccc1-n1c(C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 +Cc1nc(C)n(-c2ccc(C(=O)Nc3cccnc3N(C)C)cc2)n1 +CC(C)CCCC(C)NC(=O)N1CCOC(C(N)=O)C1 +N#Cc1cc2cc3c(cc2nc1SCC(=O)NC1CC1)OCCO3 +COc1cccc(CN(CC2CCCO2)c2ncc(F)cn2)c1 +Cc1ccc(C)c(OC(=O)CNC(=O)CC(C)(C)C)c1 +CCOc1ccc(-c2cc(C(=O)Nc3cccc(C(C)=O)c3)n[nH]2)cc1 +O=C(NCc1cccc(-c2ncc[nH]2)c1)Nc1ccc2c(c1)OCO2 +CC(C)c1nnc(C2CCN(C(=O)c3ccncc3)CC2)o1 +Cc1ccc(Br)cc1NC(=O)N1CCCC1CC(C)O +CC(C)(C)OC(=O)N1CCC(CS(=O)c2ncccc2C#N)CC1 +CC(C)(C)n1cc(NC(=O)Nc2nnc(-c3ccsc3)s2)cn1 +Cc1nc(N2CCc3nn(C)c(=O)cc3C2)c2c(C)c(C)sc2n1 +O=C(Nc1nncs1)c1ccc(N2CCOC2=O)cc1 +CCSc1ccc(NC(=O)Cn2c(C)csc2=O)cn1 +Cc1ccc(C(=O)NCC(C)N2CCc3ccccc32)c(C)n1 +O=C(NCC1Cc2ccccc2O1)c1ccc(-c2ccccc2)[nH]c1=O +CC(C)(C)OC(=O)N1CCCC1CS(=O)c1ccncc1 +CCc1cn[nH]c1C1CCCN(C(=O)c2c[nH]c(=O)[nH]2)C1 +CC1CCC(NC(=O)c2n[nH]nc2Nc2ccccc2F)CC1 +Cc1ccc2c(c1)nc(C(=O)NC(C)c1ccccc1)n2C +CC(c1cc(F)ccc1F)N(C)C(=O)CCCn1cncn1 +Cc1cc(C)c(NC(=O)C(O)c2ccc(Cl)cc2)c(C)c1 +COc1ccc(F)cc1C(C)NC(=O)CN(C)S(C)(=O)=O +COc1ccc(CCNC(=O)c2ccoc2C(F)(F)F)cc1OC +COc1cc(OC)cc(C(=O)Nc2cccc(C(N)=O)c2)c1 +O=C(Nc1ccc(NC2CCCOC2)cc1)c1ccco1 +Cc1sc2nc(CSc3ncccn3)nc(N)c2c1C +COC(=O)N1CCC(NC(=O)Cc2ccc(-n3cccn3)cc2)CC1 +CCOc1cc(NCc2ccncc2)nc(C2CC2)n1 +CC(CC(=O)N1CCNCC1)Oc1ccc2c(c1)OCO2 +CC(C)C(=O)NCCNC(=O)NC(C)c1cccc(N2CCCC2)c1 +CN(CCc1noc(-c2ccc(F)cc2)n1)C(=O)NCc1ccco1 +O=C(Nc1ccccc1)Nc1ccc(NC(=O)c2ccoc2)cc1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCc1cc2ccccc2o1 +Nc1ccc(F)c(NC(=O)c2cc(Cl)ccc2Cl)c1 +COc1ccc(N(Cc2ccc(F)cc2)S(C)(=O)=O)c(OC)c1 +Cc1oc(C(C)C)cc1C(=O)NCC1CCCN(S(C)(=O)=O)C1 +Cc1cc(CNC(=O)c2[nH]nc(C)c2Br)cc(C)c1O +COc1ccc(-c2cnnc(N)n2)cc1C(C)(C)C +O=C(CCSc1ccccc1)N(CC(F)(F)F)c1ccccn1 +CN(Cc1nnc2n1CCCCC2)C(=O)C1CC=CCC1 +Cc1ccc(CNC(=O)c2cc3occ(-c4cccnc4)c3[nH]2)o1 +CC(C)(C)NS(=O)(=O)c1ccccc1NC(=O)C1CC1 +Cc1ccncc1NC(=O)N1CCn2c(nnc2C(F)(F)F)C1 +Cc1ccccc1NC(=O)CCC1=NS(=O)(=O)c2ccccc2N1 +CN(CC(=O)NCc1ccccc1Cl)S(C)(=O)=O +COc1ccccc1COC(=O)C(N)c1ccccc1 +CC(CNC(=O)CCOc1ccccc1F)N1CCOCC1 +Cn1c(=O)c2c(ncn2CC(=O)N2Cc3cncnc3C2)n(C)c1=O +CC(CO)NC(=O)Nc1ccc2c(c1)OC(C)(C)O2 +CCNC(CCN1CCOCC1)c1cccc(Br)c1 +COCC(C)(NC(=O)c1cc(C2CC2)nc2ccccc12)C(N)=O +Cn1c(=O)c2cc(NC(=O)CCc3ccccc3)cnc2n(C)c1=O +CC(C)c1ncc(Cl)c(C(=O)Nc2cncnc2N(C)C)n1 +CC1(NC(=O)CSc2nnnn2C2CC2)Cc2ccccc2C1 +CCS(=O)(=O)N1CCc2c(ncnc2N2CCOCC2)C1 +CC(NC(=O)c1cccc2ncccc12)c1nnc2ccccn12 +CNC(=O)C1CN(Cc2ccc3c(c2)OCO3)CCN1C(=O)C1CC1 +N#CCOc1cccc(CC(=O)N2CCOc3ccccc32)c1 +O=C(c1ccc2nc(-c3ccccc3)cn2c1)N1CCC(CO)CC1 +CCn1ncc(S(=O)(=O)NCCCn2cc(Cl)c(C)n2)c1C +CN(CCN1CCCC1=O)Cc1cnc(C(C)(C)C)s1 +CC(=O)NC(C)c1ccc(C(=O)c2cc3ccccc3o2)cc1 +CCOC(=O)CNC(=O)C1CC(=O)N(c2ccc(C)c(C)c2)C1 +COc1ccc(OC)c(CCOc2cccc(CO)c2)c1 +CCOc1ccc(NC(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1 +COc1ccc(C)cc1NCCc1nc(C)c(C)s1 +Nc1ncnc(Nc2ccc(S(=O)(=O)N3CCOCC3)cc2)n1 +Cc1csc(=O)n1CC(=O)N(CCC#N)CCC#N +CC(=O)N1CCN(S(=O)(=O)N2CCN(C)CC2)CC1 +O=C(CNC(=O)Cc1ccccc1)NCCc1ccccc1 +CC(C(=O)NCCc1ccccn1)c1cccs1 +OCc1ccccc1N1CCN(c2ccccc2)CC1 +C=CCn1c(C)cc(-c2csc(NC(=O)C3CCCO3)n2)c1C +COc1ccc(CCC(=O)N2CCc3ccccc32)cc1N +Cc1ccc(CCNC(=O)NC(C)(C)c2ncc(C)s2)cn1 +Cc1ccc(NC(=O)C2CCN(C(=O)NC3CC3)CC2)cc1C +CCOC(=O)c1ccc2[nH]cc(C(C)=O)c(=O)c2c1 +COC(=O)c1cc(CN(C)C(=O)Cn2ccc3ccccc32)oc1C +O=C(CSc1ccccc1F)NCC(F)(F)F +Cc1nc2ccccc2n(Cc2nccn2C2CC2)c1=O +FC(F)(F)CN1CCN(Cc2nnc(-c3ccco3)o2)CC1 +O=C(C1CCCC1)N1CCN(Cc2ccc(Cl)cc2)CC1 +CC(C)C(O)C(=O)N1CCC(O)(c2cccc(C(F)(F)F)c2)CC1 +Cc1nc(CNC(=O)CNC(=O)c2ccccc2)no1 +Cc1nc(C(C)NC(=O)c2cc(COc3ccccc3)[nH]n2)cs1 +CCCNC(=O)CNC(=O)C1COc2ccccc2O1 +O=C(Oc1ccc(F)cc1)C1CCCN1C(=O)Cc1cccs1 +Cc1nn(C)c(C)c1S(=O)(=O)NC(C)c1ccccc1F +COc1cccc(-c2nnc3sc(NC(=O)CC(C)C)nn23)c1 +CC(=O)NCCCS(=O)(=O)c1ccc(Br)cc1 +COCCc1nc(N)cc(Nc2ccc(C)c(Cl)c2)n1 +O=S1(=O)CCCN1c1cc(NCc2cncs2)ccc1F +CCOc1cccc(C(=O)Nc2ccc(CCC(=O)N(C)C)cc2)c1 +N#Cc1cc(F)ccc1NC(=O)NCCc1cccc2cccnc12 +Cc1cc(C)n(CCCNc2cc(N3CCCC3CO)ncn2)n1 +Nc1ccccc1C(=O)NCC(=O)c1ccc(F)cc1 +CSc1cc(C(=O)Nc2cc(C(F)(F)F)n[nH]2)ccn1 +CN(C)C(=O)C1CCN(C(=O)c2cccc3c2OCO3)CC1 +O=C(Nc1ccccc1)C1CCCN1C(=O)c1cccs1 +CC(C)C(=O)N1CCN(c2ncc(S(N)(=O)=O)s2)CC1 +CC(C)Cc1cc(C(=O)Nc2ccc(N3CCOCC3)nc2)[nH]n1 +Cc1n[nH]c(C)c1CCC(=O)NCc1ccc(NC(=O)C(C)C)cc1 +CCCCNC(=O)CC1CCN(C(=O)C2N=C(C)C=C2C)CC1 +Cc1ccc(C(C#N)N(C)C(=O)c2ccc(Cl)cc2)cc1 +Cc1ccc(C(O)C(=O)N(C)CCc2ccncc2)c(C)c1 +COc1cccc(-c2nnn(-c3ccc(C)cc3O)c2N)c1 +COc1cccc(OCc2cc(C(=O)NCc3ccco3)n[nH]2)c1 +Cc1cc(NC(=O)CCCCCc2cccs2)no1 +COc1cc(C(=O)NC(C)CO)cc(OC)c1OC +Cc1ccccc1Oc1ncccc1CNC(=O)C1CCC1 +CC1C(=O)NCCN1c1nc(C2CCCC2)nc2c1cnn2C +Cc1nc(CC(=O)Nc2ccc(C(N)=O)c(Cl)c2)cs1 +COCCCc1nc(C)c(C(=O)Nc2ccccc2)s1 +COc1cccc(OCC(O)Cn2ccnc2-c2[nH]cnc2C)c1 +NC(=O)N1CCOC2(CCCC2COCC(=O)N2CCCC2)C1 +CCOc1cc(NC(=O)c2sc(-c3nc[nH]n3)nc2C)ccc1C +CCOc1ccccc1CNC(=O)c1cn2cc(C)ccc2n1 +CC(NC(=O)CCCn1cccn1)c1cccc(C(F)(F)F)c1 +CS(=O)(=O)c1ccc(Nc2cc(C#N)ccn2)cc1 +O=C(NCC12CC3CC(CC(C3)C1)C2)c1cnn2cccnc12 +CNS(=O)(=O)c1cc(C(=O)Nc2cc(C)ccc2C)ccc1OC +COC(=O)CCc1nc2sc3c(c2c(=O)[nH]1)CCC(C)C3 +Cc1c(C(=O)N(C)C(C)C)cnn1-c1ccncc1 +COc1ccc(S(=O)(=O)N2CCC(C#N)CC2)cc1F +COc1cc(C(C)NC(=O)Cc2ccc[nH]2)ccc1OC1CCCC1 +CCc1nc(C2CCCN(c3ncc(C(N)=O)cc3Cl)C2)no1 +O=S(=O)(c1cccc(Cl)c1)N1Cc2cncnc2C1 +COCC(C)OC(=O)c1c(-c2c(F)cccc2Cl)noc1C +Cc1nc(NCC(O)c2ccccc2)c2c(C)c(C)sc2n1 +CCNC(=O)c1cccc(CNC(=O)NCC(=O)NC2CC2)c1 +NC(C(=O)NCc1cccnc1)c1ccccc1F +O=S(=O)(N1CCCCCC1)N1CCCCC1c1ccccn1 +CCSc1nc2n(n1)C(c1ccc(Cl)cc1)C(C(N)=O)C(C)=N2 +COC(=O)C1CCCN(C(=O)c2ccc(-n3ccnn3)cc2)C1 +CC(=O)N(c1ccccc1)c1nc(COc2ccccn2)cs1 +CCOC(=O)C(Cc1ncc(-c2ccccn2)o1)NC +COc1ccccc1C(C)Nc1ccc(CN2CCCC2=O)cc1 +CN(CC(=O)NCC#Cc1ccccc1C(F)(F)F)S(C)(=O)=O +COc1ccccc1Oc1ccc(CNC(=O)c2cc(C)no2)cc1 +COc1ccc(S(=O)(=O)NCc2ccccc2)cc1C +CC1CS(=O)(=O)N(c2ccc3c(c2)OCO3)C1=O +Cc1ccccc1C1(CNC(=O)NCC(C)(O)c2ccsc2)CC1 +COc1cccc(C(=O)NCCCn2ccc3cccnc32)c1 +O=C(Nc1nc2ccc(F)cc2s1)C1CC(=O)N(C2CCCC2)C1 +O=C(Cc1ccccc1)NC1CCN(C(=O)C2CCCCC2)CC1 +CCOC(=O)c1cc(-c2c[nH]c3ccccc23)nn1C +CSc1ccccc1NC(=O)COC(=O)c1c[nH]c(=O)[nH]c1=O +CCCNC(=O)C(C#N)Cc1cc(OC)ccc1OC +CCc1ccc(C(=O)N2CCC(c3nnc4n3CCC4)CC2)o1 +Clc1cccc(CN2CCN(Cc3ccn[nH]3)CC2)c1Cl +CN(Cc1cccs1)C(=O)c1ccc(NC2CC2)nc1 +CC(C)N(Cc1cccnc1)C(=O)Nc1ccccc1Cl +O=C(NCc1ccc(=O)[nH]c1)c1ccc(-c2cnco2)cc1 +CN(C)C(=O)c1ccc(NCC2COc3ccccc3C2)nc1 +COc1ccnc(NC(=O)c2cnn(C)c2-n2cccc2)c1 +COC(=O)C(c1cc(Br)ccc1OC)C1CC1 +CCN(C(=O)Cc1c(C)nc(-c2ccccn2)[nH]c1=O)C(C)C +Cc1ccc(CC(=O)Oc2ccc(Cl)cc2Br)cn1 +CC(=O)Nc1nc2c(s1)CN(CC(=O)N1CCOCC1)CC2 +Cc1ccc(C)c(N2CCN(Cc3nnnn3C(C)(C)C)CC2)c1 +CN(Cc1ccc(Br)cc1)C(=O)CC1CC1 +Fc1ccc(NCc2ccc(F)c(F)c2F)nc1 +C=CCN1CCC2(CCN(Cc3nccs3)CC2)C1=O +Cc1cc2sc3nc(=O)c4cccnc4n3c2cc1C +CNC(=O)Cc1ccc(NC(=O)COCC(F)(F)F)cc1 +CN(C)C(=O)CN(C)C(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +Cc1cc(C)c(NC(=O)c2nc(C)c3ccccn23)c(C)c1 +CCNc1nc(N2CCOCC2)nc2c1cnn2C +COC(=O)CN1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1 +CCOc1cc(NCc2ccc(C)cc2)nc(C)n1 +CC(C)c1ccc(C2CCCN2C(=O)c2cc[nH]c(=O)c2)cc1 +NC(=O)c1ccc(NCC(=O)N2CCCCC2)cc1Cl +CC(C)C(CCO)NC(=O)Nc1ccc(Oc2cccnc2)nc1 +CCOC(=O)CNC(=O)C(N)Cc1ccccc1 +COc1ccc(CCNC(=O)c2cnc3ccsc3c2)cc1OC +Cc1cccc(-c2ncc(C(=O)Nc3cccnc3)c(N)n2)c1 +COc1cccc(C(=O)NC2CCN(c3ncc(C)c(C)n3)CC2)c1 +COc1ccc(S(=O)(=O)NC(C)c2ccc(C)o2)cc1Cl +COc1cc(C#N)c(Br)c(Br)c1OC +CCOC(=O)N1CCN(CCC(=O)Nc2cccc(F)c2)CC1 +CCOC(=O)NCCC(=O)N(C)Cc1csc2ccccc12 +Cc1ccc(O)c(NC(=O)CCCc2nc(C)no2)c1 +CCn1nc(C)c(Cl)c1C(=O)Nc1ccc(OC)c(OC)c1 +CCC(=O)N1CCc2cc(C(=O)Nc3ccc(C)c(C)c3)ccc21 +CC(=O)Nc1ccc(OCc2cccc(C#N)c2)c(Cl)c1 +CCOC(=O)CN1CCN(C(=O)c2ccc(C)s2)CC1 +COc1ccc(OC)c(C(=O)COC(=O)c2ccc(C)o2)c1 +COC(=O)NC(Nc1ccccc1)(C(F)(F)F)C(F)(F)F +NC(=O)c1csc(C(=O)N(CC2CCC2)CC(F)(F)F)c1 +CCN(Cc1cccs1)C(=O)NCC1CN2CCCCC2CO1 +N#Cc1cc(C(F)(F)F)ccc1N1CCN(Cc2ccncc2)CC1 +COCCCNS(=O)(=O)c1ccc(C(C)O)cc1 +N#CCCc1ccc2[nH]c(C3CCCCC3)nc2c1 +CCN1CC(COC(=O)c2sccc2C)CC1=O +CC1CCN(c2ccc(C(=O)Nc3cnn(CC(N)=O)c3)cn2)CC1 +CCc1cccc(C)c1NC(=O)CS(=O)(=O)c1ccc(C)cc1C +CCCCC(=O)Nc1ccc(OC)c(S(N)(=O)=O)c1 +CCCc1n[nH]c(C2CN(C(=O)c3ccc4[nH]nnc4c3)CCO2)n1 +O=C(NCCc1cnn(-c2ccccc2)c1)c1scnc1C1CC1 +Cc1nc2cccnc2n1C1CCN(C(=O)Nc2ccccc2)C1 +COc1ccc(S(=O)(=O)NC(C)C#N)cc1Cl +COC(=O)C(C)N1C(=O)C(C)Oc2ccc(CO)cc21 +N#Cc1ccc(C(=O)NCC(=O)NCCc2ccc(F)cc2F)cc1 +COc1cc(CNC(=O)NCC(C)C)ccc1O +COc1ccc(Cl)cc1NC(=O)c1n[nH]cc1Cl +Cc1ccc(-n2nc(N)cc2C)cc1Br +COC(=O)c1sc(NC(=O)C2CC=CCC2)nc1C +Cc1ncccc1C(=O)N1CCC(O)(c2cccnc2F)CC1 +COc1ccc2c(CC(=O)N3CC(C)OC(C)C3)coc2c1 +CC1(C(=O)Nc2ccc(-n3ccnc3)cc2)Oc2ccccc2NC1=O +COc1ccc(OC)c(-c2csc(=O)s2)c1 +NC(=O)Cn1cc(NC(=O)CC2CC3CCC2C3)cn1 +C=C(C)COc1ccccc1C(=O)N1CCCOCC1 +Cc1cc(C(=O)NC2CCCCC2)nc2nccn12 +COc1ccc(C(=O)Nc2ccc(Sc3nccn3C)cc2)nn1 +Nc1ccccc1SCC(=O)Nc1ccc(Cl)cn1 +N#CCCN(CCC(F)(F)F)C(=O)c1cccc2cn[nH]c12 +CCc1nc(C2CCCN(C(=O)CC(C)n3cccc3)C2)no1 +Cc1ccc(CCNC(=O)CNC(=O)c2cc3ccccn3n2)o1 +Cc1cccnc1NC(=O)Cn1nc(-c2cccs2)ccc1=O +COC(=O)C(NCc1ccc[nH]1)c1ccc(F)cc1 +O=C(Cn1ccccc1=O)NCc1cccc(OCc2ccccc2)c1 +CCCOc1ccc(S(=O)(=O)NCC)c2ccccc12 +N#Cc1ccc(OCC(=O)NCCc2nc3ccccc3[nH]2)cc1 +COc1ccc(NC(=O)CSc2cc(C)[nH]c(=O)n2)c(OC)c1 +CC(=O)N1CCc2ccccc2C1CC(=O)NCc1cc[nH]n1 +CC(=O)N1CCc2cc(S(=O)(=O)NCCc3ccccn3)ccc21 +O=C1Nc2ccccc2SC1CC(=O)N1CCOCC1C1CC1 +Fc1cc(Cl)cc2c1CCNC2c1cccnc1F +CN(C(=O)CCNC(=O)C(C)(C)C)C(C(N)=O)c1cccc(F)c1 +Cc1cc(O)ccc1-n1nnc(-c2ccncc2)c1N +O=C(CNc1nc2cc(Cl)ccc2s1)NC1CC1 +COc1cc(CNC(=O)Nc2ccccc2Br)ccn1 +CC1CC1c1ccc(CN(C(=O)NCCc2cnn(C)c2)C2CC2)o1 +C#CCOC(=O)Cn1cnc2ccc(F)cc2c1=O +Cc1nn(C)c2sc(C(=O)N3CCCC(C(N)=O)C3)cc12 +CCc1ccc(-c2nccn2C(CC)c2nc(C)no2)nc1 +Cn1ncc2c1CCCC2NC(=O)c1ccccc1F +O=C(Cn1nc2sc3ccccc3n2c(=O)c1=O)c1cccs1 +N#CCCN(CCc1ccccc1)C(=O)c1cc(Cl)cc(Cl)c1 +O=C(COc1ccccc1)N1CCN(c2nc3ncccc3o2)CC1 +O=C(c1cccc(-c2cn[nH]c2)c1)N1CCC(O)C1 +CCN(c1ccc(C(=O)NCc2nncn2C)cc1)C(C)C +O=C(NCc1n[nH]c2c1CCCCC2)c1ccc(-n2cnnn2)cc1 +CC(C)n1nccc1NC(=O)CCSc1ccc(Cl)cc1 +NS(=O)(=O)c1ccc(Oc2ccc(Br)cc2F)cc1 +Cc1cccc(NC(=O)CSc2c3c(nc4ccccc24)CCC3)n1 +Cc1nc(N2CCN(c3ncc(Cl)cn3)CC2)sc1C +Nc1cccc2c1CCN(c1ccc(S(N)(=O)=O)cc1)C2 +O=C(NCCCNC(=O)c1sccc1C1CC1)c1cccc(O)c1 +CC(=O)NC(C)(C)c1noc(C(C)Oc2cccc(C)c2)n1 +CCN(C(=O)c1nc(-c2ccncc2)no1)c1ccccc1 +COCc1nc2ncc3c(=O)n(-c4ccc(C(C)=O)cc4)ccc3n2n1 +O=C(NCCOCc1ccccc1)NCC1CN2CCCCC2CO1 +Cc1cc2cc(NC(=O)CNC(=O)c3cc(C)oc3C)ccc2[nH]1 +Cc1cccc(C(=O)N2CCC3(CC2)COCCN3CC2CC2)c1 +O=C(Nc1cccc(Cl)c1)c1ccc2c(c1)[nH]c(=O)c1ccncc12 +CCc1nc(NCCCO)c2cc(CC)sc2n1 +CNC(=O)c1cc(NC(=O)N(C)C(C)c2ccccc2)ccc1F +COc1ccc2c(c1)nc(C)n2Cc1cccnc1 +Cc1ccc(-n2ncc(C(=O)N3CCN(C)CC3)c2C(C)C)cc1 +CCCn1cc(CCNC(=O)Cc2cccc(F)c2)c2cccnc21 +CCc1nnc2n1CCN(CC(=O)N(CC)C1=CCCCC1)C2 +O=C(NCc1csc(=O)[nH]1)C1CC1c1ccc2ccccc2c1 +CC(C)c1cccc(C(C)C)c1NC(=O)CN1CCOCC1C1CC1 +O=C(NC1CCCC1)c1ccccc1CN1CCOCC1 +CNC(=O)NCC(=O)Nc1ccc(F)cc1OC(F)F +CN(C(=O)C1COc2ccc(F)cc2C1)c1nccs1 +CCc1ccc(C2(Cc3cccc(C)c3)NC(N)=NC2=O)cc1 +COCCOc1ncccc1C(=O)Oc1ccccc1 +CC(C(=O)N1CCN(c2cccc(Cl)c2)CC1)n1cncn1 +O=C(CCc1nc(-c2ccsc2)no1)N1CCOC2CCCCC21 +Cc1cc(-c2nc3c4cnn(C)c4ncn3n2)n[nH]1 +COCCCNC(=O)c1nc2c(s1)CCCN2c1ccc(C)nn1 +CCC(C)n1c(N)nc2c(=O)n(C)c(=O)n(C)c21 +CCOCCC(=O)C(C#N)c1ccc(C)c(OC)c1 +CC(C)COc1ccccc1NC(=O)C1CCC(=O)NC1 +CC(C)C(C)NC(=O)CNc1ccc(C(=O)N2CCOCC2)cc1 +OCC1COCCN(c2nnc(-c3ccccc3)s2)C1 +Cc1cc(C)n2nc(C)c(C(=O)N3CCC(OCC(C)C)CC3)c2n1 +CCOc1cc(C(=O)Nc2cccc(O)c2)ccc1OC +CC(=O)Nc1ccc2c(c1)NC1CN(C3=CC4=CC=NC4C=C3)CCN21 +Cc1nc(CN(C)C(=O)Nc2nc(-c3ccccc3)ns2)cs1 +Cc1nn(CCO)c(C)c1CN1CCOC(C)(c2ccccc2)C1 +Cc1ccc(NC(=O)N(C)C)c(C(=O)NCc2ccccn2)c1 +O=C(Cn1cnc(-c2ccc(F)cc2)cc1=O)N1CCc2ccccc21 +Cc1noc2nc(C3CC3)cc(C(=O)Nc3cccc(F)c3)c12 +COC(=O)N1CCC(NC(=O)Cn2ccccc2=O)CC1 +CN1C(=O)c2cc(Cl)ccc2NC1c1cccc(F)c1 +COc1ccccc1OCCn1c(C2CC2)nc2ccccc21 +CCC1CCC(NS(=O)(=O)Cc2cccc(C#N)c2)CC1 +Cn1cccc1C(=O)N1CCC2(CC(NS(C)(=O)=O)CCO2)C1 +CCC(C)NC(=O)Cn1c2ccccc2c2nc(=O)cc(C)n21 +CC(=O)Nc1cccc(Cl)c1N1CCN(C(=O)C(C)C)CC1 +COc1ccc(F)cc1C(C)Nc1cncc(-n2cccn2)n1 +O=C(c1cccc(-n2cccn2)c1)N1CCC(c2ccncc2)CC1 +O=C(c1cccc(F)c1)N1CCC2(CC1)Cc1ccccc1C2=O +CC(C)(C)c1nnc(NC(=O)NCCOc2cccc(F)c2)s1 +C=CCOC(=O)N1CC(C)NCC1c1ccccc1 +C=CCn1c(SCC(=O)NC2CCCC2)nnc1C1CC1 +CCCNC(=O)CSc1nnc(-c2cccs2)o1 +Cc1cc(NC(=O)NCc2ccnc(OC3CCC3)c2)nn1C +CCCCC(=O)Nc1ccc(OCC)c(CO)c1 +CCCc1nnc(NC(=O)N(Cc2ccccc2OC)C2CC2)s1 +CCN(CC)C(=O)c1ccccc1NC(=O)c1cc(F)cc(F)c1 +Cn1c(=O)n(C)c2cc(NCc3ccccc3-n3cccn3)ccc21 +Cc1nnc(NC(=O)N2CCCC2c2nonc2C)s1 +COc1ccc(Cl)cc1NC(=O)c1coc(NC(=O)C2CC2)n1 +CC(Sc1nncs1)C(=O)Nc1cnn(C(C)(C)C)c1 +Cc1nn(Cc2ccccc2)c(C)c1CN1CCN(CC(F)F)CC1 +O=C(NCC1CCCO1)C1CN(C(=O)c2cccs2)C1 +CC(NC(=O)COc1ccc(F)cc1Cl)C1CCCO1 +Cc1nccn1-c1ccc(NC(=O)Cc2c(F)cccc2F)cn1 +O=C(Cn1ncc(=O)c2ccccc21)N1CCOc2ccc(F)cc21 +Cc1cc(F)ccc1NC(=O)C(C)OCC(C)C +Nc1cccc(Br)c1Br +Cc1ccc(C(C)NC(=O)Nc2cnn(CC(F)F)c2)cc1F +O=C(Cn1c(=O)oc2ccccc21)NCCc1ccccc1 +Cc1nn(C)c(C)c1CNc1ccn(-c2ncccc2Cl)n1 +Cc1ccc(NCc2ccc(F)c(F)c2F)cn1 +CCN(C)S(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1csc(=O)n1CCC(=O)OCC1COc2ccccc2O1 +C=CCNc1c(C(=O)OCC)cnc2c1c(-c1ccccc1)nn2C +CCOc1ccc(CC(=O)N2CCCC2c2cc(C)no2)cc1 +Cc1cc(C(=O)N2CCC(=O)CC2)c2ccccc2n1 +COc1cccc(CN(CC2CCCO2)C(=O)NC2CC2)c1 +COc1cccc(CCC(=O)N2CCNC(=O)C2c2ccccc2)c1 +COc1ccc(C(=O)NCc2cc(-c3cccs3)on2)cc1 +CC(NC(N)=O)C(=O)Nc1cccc(C(=O)N2CCCCC2)c1 +CCOc1ccc2c(c1)CN(C(=O)Cc1cn3ccccc3n1)CC2 +Cc1nc2ccc(NC(=O)C(Cc3ccccc3)NC(N)=O)cc2o1 +O=C(CNC(=O)c1n[nH]c2ccccc12)NC1CCCCC1 +Cn1cccc1C(=O)N1CCNC(C(=O)NC2CCCNC2=O)C1 +COc1ccc(-c2cc(C(=O)NC3CCCC3)no2)cc1OC +O=C(Cc1ccc[nH]1)Nc1cccn(Cc2ccc(F)cc2)c1=O +Cn1cnc2cc(C(=O)N(CCO)Cc3ccsc3)ccc21 +COc1ccccc1N1CCN(Cc2noc(C)n2)CC1 +Cc1n[nH]c(C2CN(C(=O)C(C)OCC(F)(F)F)CCO2)n1 +CN(C(=O)Cc1c[nH]c2ccccc12)C(C#N)c1cccs1 +COc1ccc(N(C(C)C(=O)NC2CCCC2)S(C)(=O)=O)cc1 +Cc1cnc(C(=O)N2CCCC2c2ccc3c(c2)OCCO3)cn1 +CC1CCC(NC(=O)c2cccc(-n3cccn3)n2)CC1 +O=C(Cc1cccnc1)N1CCCC1c1noc(C2CC2)n1 +CC(=O)c1sc(NCC(=O)c2ccc(F)cc2)nc1C +COC(=O)c1cc(-c2ccc(OC)cc2OC)on1 +O=C(CN1CCOc2ccc(F)cc21)N1CCOCC1 +CCc1ccc(CNc2ncccc2S(N)(=O)=O)cc1 +Cc1cc(C(=O)OCC(=O)N2CCc3ccccc3C2)c(C)o1 +Cc1nnsc1C(=O)N1CC(C(=O)NCC2CC2)C1 +CN(CC(=O)N1CCNC(=O)C1)c1nc2c(F)cccc2s1 +CCn1cnnc1CNC(=O)C1CC1c1ccccc1C(F)(F)F +Cc1nc(-c2cccc(C(=O)NCc3ccco3)c2)no1 +CCCC(NC(=O)NCc1ccc(F)cc1)C(N)=O +Cc1ccc(NCc2nnc(C3CC3)o2)c(OCC(F)(F)F)c1 +Cc1ccc2c(c1)nc(C(=O)Nc1cccc(C#N)c1)n2C +Cc1cccc(NC(=O)c2c[nH]c3ccccc23)c1 +CCn1cnnc1CNC(=O)NCc1ccncc1 +CCCc1oc(-c2c(OC)cccc2OC)cc1CO +Nc1nc(N)nc(COC(=O)c2ccccc2Cc2ccccc2)n1 +Cc1ccc(SCCC(=O)Nc2cccnc2)cc1C +O=C(Nc1cccc(Cl)c1)N1CCN(C(=O)C2CCCO2)CC1 +CCNC(=O)COc1ccc(-c2ccccc2)nc1 +Cc1ccc(F)cc1NC(=O)Cn1nc(-c2ccco2)cc(N)c1=O +CC(Cn1ncc2ccccc2c1=O)Nc1nccnc1OC(C)C +CCOc1ccc(F)c(C(=O)N(C)CC(=O)N(C)C)c1F +CC(C(=O)Nc1ccccn1)S(=O)(=O)c1ccc(F)cc1 +CCN1C(=O)NC(c2cccc(C#N)c2)C(C(=O)OC)=C1C +Cc1c(Cl)cccc1OCc1nc(-c2ccncc2)no1 +COc1ccc2c(CC(=O)Oc3ccc4cn[nH]c4c3)coc2c1 +COCCCNC(=O)C(N)c1cccc(C)c1F +CCC(C)NC(=O)NCc1ccc2c(c1)OCCO2 +COc1ccccc1Cn1cc(C)c(C)c(C#N)c1=O +CCOC(=O)C(O)(c1ccc2c(c1)CCN2)C(F)(F)F +Cc1csc(C(C#N)C(=O)C(C)Oc2ccc(C(C)(C)C)cc2)n1 +Cc1cc(C(=O)NCC(O)c2ccc(C(C)C)cc2)n(C)n1 +CCOC(=O)C1CCC(NC(=O)c2scnc2C2CC2)C1 +Cc1cnc(NC(=O)N2CCOC(C)(C)C2)s1 +CCCC(=O)NCC1CCCN(C(=O)c2cccc(Cl)c2)C1 +CCc1nc2n(n1)CCCC2NC(=O)C(C)Oc1ccccc1C#N +Cc1c(-c2ccncc2)n[nH]c1NC(=O)Cc1ccc2c(c1)CCO2 +O=C(c1cccc(-c2ccoc2)c1)N1CCC(c2ccn[nH]2)CC1 +NC(=O)c1ccc(NC(=O)c2nccc3c(F)ccc(N)c23)cc1 +CCC(NC(=O)N(Cc1ccccc1F)C1CCC1)c1noc(C)n1 +COc1ccc(Cn2ccc3c2CCCC3O)cn1 +CC(OC(=O)CCc1ccc(-c2ccccc2)o1)C(N)=O +Cc1cccc(N2CCN(C(=O)Cc3ccc(C)nc3)CC2)c1 +Cc1cc(Cl)c2nc(-c3cccnc3)c(N)n2c1 +Cc1occc1COC(=O)CCc1nc(-c2ccco2)no1 +CC(=O)NCC(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1 +CC(Oc1ccccc1C(F)(F)F)C(=O)N1CCN(CCO)CC1 +COc1ccc(NC(=O)c2cc(-c3cccnc3)[nH]n2)cc1OC +CN(C)c1ccc(NC(=O)CCn2ccc3ccccc32)cn1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1cc2ncccn2n1 +CCOc1cc2c(cc1O)C(c1ccc(O)cc1)NCC2 +Cc1ccc(C(=O)NCC(=O)NCc2c[nH]nc2C)cc1 +CC(C(=O)N1CCCCCC1)S(=O)(=O)c1ccccc1F +COc1ccc(-c2nnc3cc(C)ccn23)cc1N +NC(=O)COc1ccc(OCc2cccnc2)cc1 +Cc1ccc2ncc(C(=O)NC(C)c3c(C)noc3C)n2c1 +Cn1c(N)c(N2CCN(c3ccc(F)cc3)CC2)c(=O)n(C)c1=O +O=C(COc1cccc2ccc(=O)[nH]c12)Nc1ccccc1 +O=C(Nc1nc(-c2ccc3c(c2)CCCC3)cs1)C1CCCO1 +Cc1cccc(C(C)C)c1NC(=O)c1cnc2c(c1)c(C)nn2C +CCN(CCOc1cc(C)c(N)c(C)n1)c1ccccc1 +Cc1onc(-c2ccccc2)c1C(=O)Nc1ccc(F)cc1F +c1ccc(Nc2nn(-c3ncccn3)c3c2CNCC3)cc1 +Cc1ccc(C)c(CC2Oc3ccc(N)cc3NC2=O)c1 +COc1ccc(NC(=O)Nc2ccc(NC(C)=O)cc2)cc1 +CC(C)N(Cc1cccnc1)C(=O)Nc1cnc(C(C)(C)C)nc1 +O=C(NCc1ccccn1)C12COCC1CN(Cc1cccnc1)C2 +CCC(C)NC(=O)CCNC(=O)NCc1nc(C)cs1 +CC(=O)Nc1nc2ccc(NC(=O)c3cccc(C)c3)cc2s1 +COc1ccccc1OCC(=O)N1CCC(Oc2cccnn2)CC1 +CCCCc1nnc(NC(=O)c2ccn(-c3ccc(F)cc3)n2)s1 +O=C(NCc1ccc(F)cc1)c1cc(-c2ccc3c(c2)OCO3)on1 +CC1(C)C2CCC1(C)C(NC(=O)CCNC(N)=O)C2 +COC(=O)N1CCCN(C(=O)Nc2ccc(OC)cc2OC)CC1 +CC(C)(C)c1ccc(OC(=O)CCC(=O)N2CCOCC2)cc1 +CCN1CCN(C(=O)CCC(C#N)CC(C)C)CC1 +O=S(=O)(NCCNc1ccc2ccccc2n1)N1CCOCC1 +CCCCCNC(=O)c1cc(=O)[nH]c2ccccc12 +Cc1ccc(Cn2nccc2NC(=O)C(C)OCC(F)(F)F)cc1 +CNc1snc(C)c1C(=O)Nc1cccc(OC(F)(F)F)c1 +CCc1cc(=O)n(CCNC(=O)c2ccc(Cl)c(Cl)c2)cn1 +Cn1ccc(C(=O)N2CCCC(c3cc(=O)nc4n3CCC4)C2)n1 +COc1ccc(CNC(=O)NCc2ccnc(OC3CCC3)c2)cn1 +Cc1cccc(NC(=O)COc2ccc(-c3nnco3)cc2)c1C +O=C(Cc1cccc(F)c1F)OCC(=O)N1CCCCCC1 +Oc1cccc(CNCCc2cnn(-c3ccccc3)c2)c1 +Nc1cc(F)ccc1NC(=O)CN1CCCC1=O +CC(Sc1nccn1Cc1ccccc1)C(N)=O +CSc1ccc(NC(=O)NC2c3ccccc3CC2O)cc1 +CN(Cc1ccc(C#N)cc1)c1ncnc2c1cnn2C +Cc1nc(-c2ccc(C)c(S(=O)(=O)NC3CCCC3)c2)no1 +CCCOCC(=O)NC(C)(C)c1cccc(Cl)c1 +Cc1ncc(CNC(=O)c2cc(Cl)cc3cccnc23)s1 +CC(C)OC(=O)C1CCCN1Cc1cccc(-n2cccn2)c1 +CN(C)C(=O)c1ccc(CN2CCN(CC(F)F)CC2)[nH]1 +O=C(c1cc(=O)c2ccccc2o1)N1CCOC12CCCCC2 +O=C1NCCCn2cc(S(=O)(=O)N3CCCCCC3)cc21 +CC(C)c1nnnn1CC(=O)N1CC(C)(C)Sc2ccccc21 +CC1CCCCC1OCC(=O)Nc1ccc(F)c(N)c1 +Cc1ccc2c(-c3ncc(C)c(N)n3)cccc2n1 +Cc1cc(C)n(-c2ccc(C(=O)Nc3nc4c(s3)CCC4)cc2)n1 +Cc1ccc(-c2c(C)sc3nc(C)n(N)c(=O)c23)cc1C +CNc1cccc(-c2cc(=O)c3cc4c(cc3[nH]2)OCO4)c1 +CCn1nc(C(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1=O +CCc1cccc(CC)c1NC(=O)c1ccc(-c2nc(C)no2)cc1 +CN(C(=O)CN1CCN(S(C)(=O)=O)CC1)c1nccs1 +COC(=O)c1cc(C#N)c(=O)n(Cc2csc(C3CCCC3)n2)c1 +COCCCOc1ccccc1NC(=O)N1CCCC1 +Cc1noc(C2CCN(C(=O)c3ccc(OC(F)F)cc3)CC2)n1 +Cn1cc(C(=O)NC2(c3cccc(Cl)c3)CC2)ccc1=O +C#CCN1C(=O)c2ccccc2NC1c1ccc(OCC#N)cc1 +COC(=O)C(C)NS(=O)(=O)CCc1ccccn1 +CCc1onc(C)c1NC(=O)CCOc1ccccc1C(C)C +CC(C)N(Cc1nccn1Cc1c(F)cccc1Cl)C(=O)C1CC1 +Cc1ccc(N2CC(C)N(C(=O)Cc3cccc(O)c3)CC2=O)cc1 +CCCN(CCc1ccccn1)C(=O)c1ccc(Cl)cc1 +COc1ccc(C(O)c2nc(C)nn2-c2ccccn2)cc1 +CCn1cc(-c2c(C#N)c(N)nc3c2CCc2c(O)cccc2-3)cn1 +CC(C)CCCNS(=O)(=O)c1ccc(O)cc1 +O=C(CSc1ccc2ccccc2n1)NC1CCCc2ccccc21 +CNC(=O)c1cccc(CCNC(=O)N(C)Cc2nc(C)cs2)c1 +O=C(Nc1ccc(-n2cncn2)cc1)c1cc(Cl)ccc1F +O=C(NCCNC(=O)c1ccc2cncn2c1)c1ccc(Cl)cc1 +N#CC1(CS(=O)(=O)N2CCN(c3cccc(Cl)c3)CC2)CC1 +Cc1cccc(C2CN(c3cnccn3)CCO2)n1 +O=S(=O)(c1ccc(N2CCC(O)CC2)cc1)C(F)(F)F +Cc1ccc(-n2nnnc2SCC(=O)C(C)(C)C)c(C)c1 +CC(=O)NCc1ccc(C(=O)Nc2nc(C)no2)cc1 +O=C1Nc2ccccc2SC1Cc1nc(Cc2ccccc2)no1 +CCOc1ccccc1NCC(=O)Nc1ccc(OC)cc1 +Nc1nc2ncccc2cc1C(=O)Nc1ccc(F)cc1 +O=C(C1CCCCN1c1ncc(Cl)cn1)N1CCOCC1 +CC(C)OC(=O)c1cn(CCC#N)nc1-c1ccc(F)cc1 +CCC(C)c1cc(C(=O)N2CCOC3(CCCC3)C2)on1 +CCOC(=O)Cc1c(C)[nH]c2cc(-c3ccccc3)nn2c1=O +O=C(NCC1(Sc2ccccc2)CCOCC1)C1CCC1 +Cc1ccc(S(=O)(=O)NC2CCCC2)c(C)c1 +O=C(Nc1cc(F)c(F)c(F)c1)c1ccn(-c2ccccc2)n1 +CN1CCN(C(=O)C2CC2c2ccco2)C(c2ccccc2)C1 +CN1CCN(C(=O)c2ccnc(-c3ccc(C4CCCC4)cc3)c2)CC1 +CCCOCC(=O)NC(c1ccccc1)c1nc2ccccc2n1C +CN1CCN2CCN(C(=O)c3ccc(N)nc3)CC2C1=O +O=C(c1cccc(Cl)c1)N1CCCN(C(=O)C2CCCO2)CC1 +Cc1cc(OC(C)(C)C(=O)NCC2CCCO2)ccc1Cl +CCOc1ccc(NC(=O)NCCNC(=O)c2ccccc2)cc1 +CC(C)N(Cc1cnn(C)c1)S(=O)(=O)c1cn[nH]c1 +COC(=O)c1sc(NC(=O)c2ncoc2C)nc1C1CC1 +Cc1ccc2c(CNc3ccc(C(=O)NC4CC4)cc3)cc(=O)oc2c1 +CC1(C)C(=O)N(CC(=O)NC2CC2)c2ccc(Cl)cc21 +Cc1cccc(-n2nnnc2SCC(=O)N2CCCCC2C)c1C +Cc1nn(C)c(C)c1NC(=O)C(C)N1CCCC2(C1)OCCO2 +COC(=O)N1CCc2ccc(NC(=O)c3cc(C)cs3)cc2C1 +CCOc1ccc(NC(=O)COc2cccc3c2CCNC3=O)cc1 +CC(=O)NCCNC(=O)NC(C)(C)c1ccc(F)cc1Cl +Cc1cc(CC(C)NC(=O)c2cc(S(N)(=O)=O)ccc2F)[nH]n1 +Cc1ccc(C(=O)N(C)CC(=O)N2CCOCC2)c(O)c1 +Cn1c(N)c(N2CCN(C(=O)c3ccco3)CC2)c(=O)n(C)c1=O +CC(C)Cn1c(NCCO)nc2c1c(=O)[nH]c(=O)n2C +CC1CCCC1NC(=O)C1COCCN1C(=O)OC(C)(C)C +CCOCC1CN(C(=O)Cc2ccccn2)Cc2ccnn2C1 +CCn1c(=O)oc2cc(NC(=O)Nc3ccc(F)cc3)ccc21 +N#Cc1cccc(NCCCc2ccc(O)cc2)c1 +Cc1cc(C)n(-c2ccc(SCC(=O)N3CCCCC3)nn2)n1 +Cc1nc(-c2ccccn2)[nH]c(=O)c1CC(=O)NCCCC(N)=O +Cc1cc(=O)c(C(C)(C)O)nn1-c1c(F)cccc1F +O=C(CCCc1nc(-c2ccncc2)no1)NC1CCCCC1 +CC(C)(C)C(C#N)NC(=O)Cn1nnc2ccccc2c1=O +CN(Cc1nnc(-c2cc3c(s2)CCCC3)o1)c1cnn(C)c1 +COCCNC(=O)C1CCN(c2ccc(Cl)cc2Cl)C1=O +CCN(Cc1cc(=O)c2cc(C)ccc2[nH]1)CC1CCCCO1 +O=C(NCCOc1ccccc1)c1ccc(CN2CCCC2=O)cc1 +Cc1nc(C(C)C)nc2c1CCC(=O)N2CC1CCCO1 +CSc1ncccc1C(=O)NCCCCc1ccccc1 +CNC(CCC(=O)OC)C(=O)c1c(C)c(C)cc(C)c1C +C=CCN(CC=C)C(=O)Cn1c(=O)cnc2ccccc21 +COc1ccc(Cl)cc1Cc1nc(CO)cs1 +NC(=O)C1CCCN1C(=O)c1cccc(OCC2CCCO2)c1 +CCN(CC(C)C#N)S(=O)(=O)N1CCOCC1 +Cc1cc(C)c(CNC(=O)CNC(=O)c2ccccc2)c(C)c1 +CCn1nnc(NC(=O)c2cccc3c(Br)cccc23)n1 +O=C(NCc1ccccc1-n1ccnc1)Nc1ccc2c(c1)CCC2 +Cc1cccc(OCC(=O)NC(CO)C(O)c2ccc(N)cc2)c1 +CCCC1CN(C(=O)c2ccc(C(N)=O)cc2)CCO1 +Cc1cn2c(CN(C)C(=O)C3CCOC3)c(C)nc2s1 +CC1COCC(C)N1C(=O)C1CCOc2ccccc21 +Cc1ccc(Cl)cc1NCc1ccc(C(N)=O)cc1F +O=C(NC1CCc2c(O)cccc21)c1cccnc1N1CCCC1 +CCc1ccc2nc(N3CCOCC3)c(CC#N)cc2c1 +CCCCNC(=O)c1cn(CCCC)c2cccc(N)c2c1=O +O=S(=O)(NC1CCC(O)CC1)c1csc2ccc(Cl)cc12 +COc1ccccc1OCCC(=O)N(C)Cc1ccc(F)c(F)c1 +NC(=O)c1ccccc1OC(=O)Nc1ccc(F)cc1 +CC(=O)Nc1cccc(CNC(=O)Cc2coc3cc(C)ccc23)c1 +COc1ccc(C(=O)NCC(O)(c2ccccc2)C2CC2)cc1 +CC(C)N(C)S(=O)(=O)c1cccc(C(N)=O)c1 +O=c1[nH]c2ccccc2n1CCc1nc(-c2cccnc2)no1 +CC(=O)N1CCN(C(=O)C2(C)CC2(Cl)Cl)CC1 +COCCN(Cc1ccccc1)C(=O)c1cc(OC)ccc1O +O=C(NCc1cccc(OC(F)(F)F)c1)c1cc2ccncc2cn1 +CCOC(=O)C1=C(C)C(C(=O)COc2cccc(Cl)c2)=NC1C +O=C(c1ccc(O)cc1)N1CCN(C(=O)c2ccoc2)CC1 +CC(C)c1nc2cc(NC(=O)CNC(=O)c3ccco3)ccc2o1 +CC(=O)c1cc(C(=O)NC(C)(C)CC2Cc3ccccc3C2)[nH]n1 +COCC(=O)NCC1CCC(c2nn(C)c3ncccc23)CC1 +COc1ccc2cc(C(=O)Nc3ccc(F)cc3)c(=O)oc2c1 +C=CCn1cnnc1Sc1nc2cc(C)nn2c2ccccc12 +O=C(Nc1ccn(-c2ncccc2Cl)n1)c1cccc(Cl)c1 +Cc1ccc(S(=O)(=O)NCCC(C)C)c(C)c1 +CCC(C)NS(=O)(=O)c1cc(-c2ccc(=O)n(C)n2)cs1 +Cc1nnc(NCc2ccccc2N2CCOCC2)c(C#N)c1C +CSc1ncc(C(=O)NCCC(C)C)c(C)n1 +OCc1nc2cc(F)ccc2n1C1(c2ccccc2)CC1 +O=C(CSc1ccccc1F)Nc1nccs1 +Cc1cccc(C(=O)Nc2cc(S(C)(=O)=O)ccc2Cl)c1 +O=C(c1ccc2nccn2c1)N1CCCCC1CCc1ccc(O)cc1 +COCc1nn2c(CO)c(-c3cccs3)nc2s1 +Nc1[nH]nc(-c2cn[nH]c2)c1-c1ccc(Cl)cc1Cl +CC(C)(C)C(=O)OCc1nc(-c2ccc3c(c2)OCCO3)cs1 +CCCC(=O)NCC(OC)c1ccccc1OC +Cc1nc(CNC(=O)NCC(C(C)C)N2CCOCC2)cs1 +O=C(CCCc1cc(F)ccc1F)Nc1n[nH]c(-c2ccoc2)n1 +Cn1nc(C(=O)N2CCCCCC2)cc1NC(=O)C1CCCC1 +Cc1cc2ccccc2n1CC(=O)Nc1ccccc1-n1cncn1 +Cc1occc1-c1nnc(SC2CCCC2)n1N +CCOc1cccc(C(=O)N2Cc3ccccc3CC2C(N)=O)c1 +CCCS(=O)(=O)NC1(c2ccc(F)cc2F)CCOCC1 +O=C(Nc1ccccc1F)c1cnn(-c2ccccc2)c1 +CNC(=O)Cc1ccc(NC(=O)c2cc(OC)c(OC)cc2C)cc1 +O=C(CNC(=O)N1CCN(c2ncccn2)CC1)N1CCCCC1 +O=C(Nc1ccccn1)c1nnn(-c2ccc(F)cc2)c1C1CC1 +COC(=O)C(C)(C)NC(=O)c1cnn(-c2ccccc2)c1C +CCOC(=O)CCNC(=O)Cc1c(C)nc(C)[nH]c1=O +O=C(Cn1c(=O)[nH]c2ccccc21)OCC1CCCO1 +COC(=O)c1cccc(NCc2nc(-c3ccsc3)no2)c1 +COc1cc(C(=O)N(C)C(C)c2ccccc2)cc(Cl)c1OC +CCC1CC(C(=O)NC(C)CC(=O)c2ccco2)CCO1 +Cc1ccc(=O)n(CC(=O)Nc2cccc(F)c2)n1 +CN(CCc1ccncc1)C(=O)C(O)c1ccc(F)cc1 +O=C(c1ccccc1Cl)N1CCN(C(=O)N2CCOCC2)CC1 +COc1ccc2c(C(=O)NCC3CCCC3)cc(=O)oc2c1 +CCNC(=O)c1ccc(S(=O)(=O)N2CC(C)OC(C)C2)cc1 +Cc1cccc(C(=O)Nc2cccc(C(=O)NC(C)C)c2)c1 +COc1ccccc1NC(=O)C1CC(=O)n2c(nc3ccccc32)N1 +Cc1ccc(C(=O)N2CCC3(CC2)CN(CC(C)C)C3=O)cc1 +CC1CN(C(=O)C2(N3CCOCC3)CCCCC2)CCC1(C)O +CCCNC(=O)C1CC(=O)N(c2ccc(F)c(Cl)c2)C1 +COc1cc(OC)c(NC(=O)c2cnc3c(c2)c(C)nn3C)cc1F +O=C(Cn1nnc(-c2ccccc2)n1)Nc1ccc(-n2cccn2)nc1 +CC(NC(=O)c1cccc(Cl)c1)C(=O)NC1CCCC1 +CCCCCNC(=O)c1onc(S(=O)(=O)C2CC2)c1N +C#CCOC(=O)c1ccc(Oc2ccc(C(N)=O)cc2)cc1 +CC1CN(C(=O)Nc2ccc3c(c2)OCCO3)CC(C)O1 +CC(=O)Nc1cccc(OCCNC(=O)NCc2cccc(C)c2)c1 +Cc1cc(C(=O)NCC(=O)NCc2c(C)nn(C)c2C)n(C)n1 +CCC(=O)NC1CCCN(C(=O)c2cccc(OC)c2F)C1 +CCCCNC(=O)C(C)CS(=O)(=O)N1CCNCC1 +CC(C)(C)OC(=O)NC(C(=O)CN)c1ccccc1 +Cc1cc(NC(=O)CSc2nc(-c3ccco3)n[nH]2)no1 +Cc1ccc(C(C)NC(=O)Nc2nncs2)o1 +CS(=O)(=O)N1CCC(Nc2ccc(C#N)cn2)CC1 +CC(C)(C)N1CC(C(=O)Nc2ccc(Br)cc2)CC1=O +COCCNC(=O)c1cc(NC(=O)c2ccccc2)n(C)n1 +Cc1nc(CN2CC(C)(C3CC3)CC2=O)cs1 +O=C(CN1CCOCC1)N1CCN(Cc2cccc3cn[nH]c23)CC1 +COc1ccc(CNS(=O)(=O)c2cnc[nH]2)cc1 +O=C(NCCCO)C1CCCN(S(=O)(=O)c2ccc(F)cc2)C1 +O=C(Nc1nc(-c2ccc[nH]2)cs1)c1ccco1 +C=CCOC1C(O)C(CO)OC1n1ccc(N)nc1=O +Cc1nc(N2CCCC2)nc2c1CCN(Cc1ccncc1)CC2 +CC1CCN(C(=O)C2Cc3ccccc3C(=O)O2)CC1 +CCNC(=O)N1CCN(C(=O)c2ccc3cc[nH]c3c2)CC1 +COc1ccc(C(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1OC +CC(C)c1cc(=O)[nH]c(C2CCCN2C(=O)C2CCCO2)n1 +O=C(c1ccc(OC(F)F)cc1)N1CCCC1c1ccc[nH]1 +Cc1ccc(NC(=O)CCc2c(C)nc3nc(C)nn3c2C)c(C)c1 +COc1ccc(N2CCN(C(=O)c3cccn3C)C(C)C2=O)cc1 +Cc1ccc2ncc(C(=O)N3CCN(C(C)C(N)=O)CC3)n2c1 +CCOC(=O)CN(CC)S(=O)(=O)c1cc(Cl)ccc1C +COc1cccc(C(=O)OCC(=O)Nc2ccccc2)c1 +CCCC(=O)NCC(=O)Nc1ccc(C(=O)NC(C)C)cc1C +CC(C)CNC(=O)c1nn(C)c2ccc(Cl)cc2c1=O +O=C(Nc1nc(C2CC2)cs1)c1cccc(F)c1F +Cc1noc(C2CCN(C(=O)c3cccnc3)CC2)n1 +O=C(Cc1ccc[nH]1)NCc1cccnc1OCc1ccccc1 +COc1ccc(C(C)OC(=O)c2ccc(S(C)=O)cc2)cc1F +Cc1cnc(C(=O)NC(C)c2ccc(F)c(F)c2)cn1 +CNC(=O)CNC(=O)CC(c1ccccc1)c1ccc(Cl)cc1 +Cc1c(Cl)cccc1NC(=O)CCc1nc2ccccc2c(=O)[nH]1 +NC(=O)C1(NS(=O)(=O)c2cc(Cl)cc(Cl)c2)CCCC1 +Cc1nc2cccnc2n1-c1ccc(C(=O)N2CCCCC2)cc1 +Cc1cccc(-n2ccnc2SC2CCCCNC2=O)c1C +CCNS(=O)(=O)c1cc(C)c(Br)cc1C +COc1ccccc1OCCNC(=O)c1cc2ccoc2s1 +Cc1cccc(OCCCC(=O)Nc2nccs2)c1 +COc1ccc(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)cc1 +CCCc1cc(=O)n(CC(=O)NCc2ccc3c(c2)OCO3)cn1 +CCCn1cc(N)cc1C(=O)N(C)C1CCOCC1 +O=C(Nc1cccnc1)c1cccn(Cc2cccc(Cl)c2)c1=O +O=C(Cn1ncc2ccccc2c1=O)NCc1cccc2ccccc12 +Cc1cc(SCC(=O)c2ccc(Cl)cc2)ncn1 +CCn1c(SC2CCCCC2=O)nc2sc(C)c(C)c2c1=O +CC(=O)NCc1ccnc(Oc2cc(C)cc(C)c2)c1 +CC(C)Cc1nc(CCN2CCCCC2=O)n(-c2ccccc2)n1 +COCC(NC(=O)c1nnn(-c2ccc(C)cc2)c1C)C(N)=O +CCN(CC)C(=O)c1csc(NC(=O)c2ccccc2C)n1 +COc1cc(CN(C)Cc2cnc3ncccn23)ccc1SC +CC(Cn1cncn1)NC(=O)Nc1ccn(CCc2ccncc2)n1 +Cc1cc(Br)c2c(c1)C(C(O)CO)NCC2 +CC(=O)c1csc(NC(=O)C(C)Oc2ccccc2)n1 +CC(C)N(C)S(=O)(=O)c1ccc(C(=O)N(C)c2ccccc2)cc1 +CC(C)CC(=O)Nc1nonc1-c1ccc(F)cc1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)c1cccc(OC)c1F +Cc1ccc2nc(NC(=O)CSc3nnc(C)o3)sc2c1 +O=C(COC(=O)c1cc2ccccc2s1)NC1CC1 +COC(=O)c1cc(-c2ccco2)nc2c1cnn2Cc1ccncc1 +Cc1cc(C)n(CC2CCCN2C(=O)c2cc3ccccc3[nH]2)n1 +COc1cccc(N2CCN(C(=O)C3CCC3)C(C)C2=O)c1 +O=c1cccnn1CCCNS(=O)(=O)c1ccccc1F +CS(=O)(=O)N1CCN(C(=O)Cn2ccc(N)n2)CC1 +CC(C)N(C)S(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1ccc(S(=O)CC2CCCN(C(=O)OC(C)(C)C)C2)nn1 +Cc1cc(C(=O)NC(CO)Cc2ccc(O)cc2)c(C)n1C1CC1 +Cc1cccc(-c2nc(CN3CCN(S(C)(=O)=O)CC3)no2)c1 +CC(Oc1ccc(F)cc1)C(=O)Nc1cc(N2CCOCC2)ncn1 +Cc1cccc(C(C)C)c1NC(=O)NC(CO)CC(C)C +CC(C)(C)OC(=O)N1Cc2cc(Br)cnc2C1 +c1cncc(-n2cccc2CNC2COc3ccccc3C2)c1 +N#CCCCN1CCCCC1c1nc2ccccc2s1 +CC(NC(=O)CC1OC(=O)c2ccccc21)c1ccccc1F +COc1ccccc1OCCCC(=O)Nc1c(C)cccc1C +Nc1nc(C2CCCO2)ncc1C(=O)Nc1ccccc1 +O=C(CCCc1c[nH]c2ccccc12)NC1CCC(O)CC1 +CCN(C)c1ccc(C(=O)Nc2ccc(F)cc2)cc1 +CN(C)c1nc(COc2cccc(NC(=O)C3CC3)c2)ns1 +CCCC(=O)N1CCCC1C(=O)c1cc(C)c(C)cc1OC +CNC(=O)c1cccc(CNc2ccc(-n3cccn3)c(Cl)c2)c1 +CC(C)CNC(=O)NCc1cccc(NC(=O)Cn2cccn2)c1 +Cc1cnc(CCNC(=O)c2ccc(CNC(N)=O)cc2)s1 +C#CCNC(=O)NCc1ccc(-n2cccn2)nc1 +CC(=O)Nc1nc(C(=O)NCCOc2cccc(F)c2)cs1 +O=C(CCn1ccccc1=O)Nc1ccc(Cl)cn1 +Cc1ccccc1-n1ncc(C(=O)N2CCC(C)CC2C)c1C +CCOC(=O)c1cc(-c2cc(OC)c(OC)c(OC)c2)[nH]n1 +O=C(COC1CCCC1)N1CCN(C(=O)Nc2ccc(F)cc2)CC1 +CCc1ccc(C2CC(=O)NC3=NC(N)=NC(=O)C32)cc1 +CC(C)NC(=O)N1CCCC1c1ccc(F)cc1 +CCCC(=O)N1CCC(C(=O)Nc2nc3c(s2)CCC3)CC1 +COC(=O)c1c(NC(=O)c2cnccn2)sc2c1CCCCC2 +CC=Cc1ccc(=O)n2c1C1CC(CN(C(=O)Nc3ccccc3)C1)C2 +CCC(CO)(CO)NC(=O)c1nc(-c2ccc3cc[nH]c3c2)no1 +Cc1cnc2cc(C3CCN(C(=O)C4CC4)CC3)[nH]c2n1 +O=C(COc1ccccc1)Nc1ccc(Cn2cncn2)cc1 +COC(=O)Nc1nc2c(s1)CN(C(=O)Nc1ccccc1)CC2 +COc1nn(C)cc1C(=O)Nc1ccc(C(N)=O)cc1 +Cc1noc(C)c1C(C)NC(=O)c1ccn(-c2ccc(F)cc2)n1 +N#Cc1cccc(CNC(=O)Nc2ccc3c(c2)NC(=O)CS3)c1 +O=C(Nc1ccc2oc(-c3ccccc3)nc2c1)c1ccccn1 +COC(=O)C(C)N1CCC(NC(=O)NC2CCCCC2)CC1 +C=CCN(CC=C)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +NC(=O)c1ccc(Cl)c(NC(=O)c2ccnc(F)c2)c1 +Cc1noc(C)c1CCC(=O)Nc1ccc(-n2ccnc2)nc1 +COCCn1cc(NC(=O)NCCc2c(F)cccc2F)cn1 +CCOc1ccc(S(=O)(=O)N(C)Cc2cnn(C)c2C)cc1 +CCC(=O)Nc1cccc(C(=O)Nc2cccc3cnccc23)c1 +O=c1[nH]cc(C2NCCc3c2ccc2cc[nH]c32)cc1Cl +C=CCNC(=O)c1ccc(OCc2nnnn2CC)cc1 +CN1CCC(CNC(=O)c2ccnc(-n3ccnc3)c2)c2ccccc21 +CNC(=O)Cc1ccc(NC(=O)c2c(OC)cccc2OC)cc1 +Cc1ccc(Cl)cc1NC(=O)C1CC(=O)Nc2ncnn21 +Cc1c(NC(=O)c2cccc(-c3ccoc3)c2)cnn1-c1ccccc1 +CNc1snc(C)c1C(=O)Nc1nc2c(s1)CCCCC2 +C=CCn1c(N)nnc1SCc1nc(-c2ccc(C)cc2)no1 +COc1ccc(C(C)=O)c(OC(=O)Cc2cccc(F)c2)c1 +CC(=O)NCc1ccc(-c2noc(-c3ccc(F)c(F)c3)n2)s1 +N#Cc1ccc(C(=O)NCC(=O)N2CCc3cc(F)ccc3C2)cc1 +CC(C)C1CN(C(=O)c2ccccc2C#N)CCC(=O)N1CC1CC1 +CNC(=O)CNC(=O)c1ccc(F)cc1Br +COCCN(C)C(C(=O)OC)c1ccc(F)cc1 +O=C1CCCN1c1ccc(NS(=O)(=O)C2CCCCC2)cc1 +CC(C)n1nccc1CN1CCOC(C)(C(=O)N(C)C)C1 +OCCCn1ccc(-c2cccc(-c3cncnc3)c2)n1 +Cc1cccc(NC(=O)c2cn3cc(Cl)ccc3n2)n1 +CCOC(=O)C(C)(NS(=O)(=O)c1ccc(C)cc1F)C(C)C +COCC(=O)N1CCN(C(=O)NCc2cnn(C)c2)CC1 +CC(C)(C)c1nnc(NCc2ccccc2)[nH]c1=O +Cc1cc(NC(=O)C(C)OC(=O)c2sccc2-n2cccc2)no1 +CCC(C)C(NC(=O)C(C)Oc1ccc(C#N)cc1)C(N)=O +Nc1nc(=O)n(Cc2ccccc2)c2sc3c(c12)CCC3 +CCOC(=O)Nc1cccc(NC(=O)C2CC(=O)N(C3CC3)C2)c1C +COCCNC(=O)CNS(=O)(=O)c1ccc(F)cc1Cl +COc1cc(Cl)c(COC(=O)C(C)N)cc1Cl +O=C1CC(C(=O)Nc2ccc3ccccc3c2)n2ncnc2N1 +COC(=O)Nc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 +CCN(CC)C(=O)Cc1ccc(NC(=O)NC)cc1 +CN(CCOc1ccc(F)cc1)C(=O)Nc1ccc2c(c1)COC2 +O=C1Nc2ccc(Cl)cc2C(c2ccccc2)=NC1O +N#Cc1ccccc1NCC(=O)N1CCCCCC1 +CC(=O)N1CCCc2cc(O)c(Br)cc21 +O=C(Nc1ccn(Cc2ccccc2F)n1)c1cc(F)ccc1F +CC1c2ccsc2CCN1C(=O)CCNC(=O)C(C)(C)C +CC(NC(=O)c1ccc(N2CCCCC2=O)cc1)c1cccc(F)c1 +CSc1nnc(SC(C)C(=O)NCC(F)(F)F)s1 +COC(=O)C1(NCCc2ccc(F)c(F)c2)CCC1 +COc1ccc(F)cc1COc1cccc(C(=O)NCC(C)O)c1 +CCNC(=O)N(C)Cc1csc(C#CCCO)c1 +Fc1cc2ncn(Cc3nc(C4CC4)no3)c2cc1F +c1cncc(-c2nc(Nc3cn[nH]c3)c3ccccc3n2)c1 +CC(c1ccccc1)n1nnc(CO)c1COc1ccccc1 +NC(=O)NCc1ccc(C(=O)NCc2nc3ccccc3s2)cc1 +CCC1CN(C(=O)c2cc(C)ccc2NC)CCO1 +Cc1ccc(C(=O)NCCCn2cc(Br)cn2)s1 +CCc1ccc(OCCn2c(=O)oc3cc(N)ccc32)cc1 +COCCN(CC(=O)N(C)C)C(=O)c1sc2ccccc2c1C +CC(=O)Nc1cc(NC(=O)NC(C)(CO)C2CC2)ccc1C +Cc1nc2c(c(=O)[nH]1)CCN(Cc1c(F)cccc1F)C2 +O=C(Nc1cc(-n2nnnc2C2CC2)ccc1F)c1ccccc1F +CN(C)C(=O)COc1ccc(NC(=O)NC2CCCCCC2)cc1 +O=C(C1CSc2nccc(=O)n2C1)N(CCO)Cc1ccccc1 +Cc1nc(NCCC#N)cc(-c2ccc(F)cc2)n1 +Nc1ncc(Br)cc1S(=O)(=O)NCc1cccs1 +CN1CC(C(=O)Nc2cc(F)ccc2OCC2CCCO2)CC1=O +Cc1ccc(CN(C)C(=O)Cc2n[nH]c(=O)c3ccccc23)o1 +CCn1c(=O)n(CC(=O)Nc2nc(C)no2)c2ccccc21 +COc1cccc(C(=O)Nc2cc(-c3ccccn3)no2)c1OC +CSc1ccccc1C(=O)NCCC(O)C(C)(C)C +O=C1CSc2ccc(C(=O)Oc3ccc(F)cc3)cc2N1 +N#CCCCN1CCNc2cc(Br)ccc21 +CCc1cccc(NC(=O)C2CCCN(C(C)=O)C2)c1 +CCOC(=O)c1nccn1Cc1cnn(-c2ccc(F)cc2)c1 +O=C(Nc1ccc2[nH]c(C(F)(F)F)nc2c1)c1ccccn1 +Cc1cccc(NC(=O)CCN(C)c2ccc(N)cn2)c1 +CC(C)CCNC(=O)NCc1cccc(NC(=O)C2CCCO2)c1 +CC(=O)c1cccc(NC(=O)Nc2cnc3ccccc3c2)c1 +O=C(CCC1CCCO1)OCc1ccc(F)cc1Br +CCCC(C)C(=O)NC1CCCN(c2ccccc2)C1=O +Cc1cccc(C)c1NC(=O)COc1ccc(F)cc1F +CCc1onc(C)c1NC(=O)c1cccc(CN2CCCC2=O)c1 +O=C(COC(=O)c1ccco1)Nc1ccc(Cl)cc1 +CCn1nc(C)c(NC(=O)Nc2ccc3oc(C4CC4)nc3c2)c1C +O=S(=O)(c1cccs1)N1CCCC1c1nnc2ccccn12 +O=C(Cn1cnc(-c2ccccc2)cc1=O)N1CCc2ccccc2C1 +Cc1cc(C)n(C2CN(c3nc(C(F)(F)F)nc4ccccc34)C2)n1 +CC1CCC(C(C)C)C(NS(=O)(=O)c2cc(C(N)=O)n(C)c2)C1 +COC(=O)NCC(=O)Nc1nnc(C2CC2)s1 +COC(=O)N(C)CC(=O)N1CCn2cccc2C1C +CCc1nc(C2(NC(=O)OC(C)(C)C)CCCC2)no1 +O=C(Nc1ccccc1F)c1ncc2sccn12 +CC(C)NC(=O)Cn1nnc2cc3c(cc2c1=O)OCCO3 +COc1cccc(C(=O)NCc2ccnc(OC(C)(C)C)c2)c1F +N#Cc1cccc(CNC(=O)NCC2(c3ccccc3)CCOCC2)c1 +CCCC(=O)N(C)Cc1ccccc1N1CCCC1 +Cc1ccc(NC(=O)N2CCCC2C(=O)N2CCN(C)CC2)cc1 +CCN(CC(F)(F)F)C(=O)c1ccc(N)cc1Cl +OC(CNCc1ccsc1)c1ccc(F)cc1F +CCC(C)NC(=O)c1cccc(NC(=O)c2cccs2)c1 +COc1ccc(F)cc1C1CN(C(=O)OC(C)(C)C)CCN1 +Cc1cc(S(=O)(=O)NC(C(=O)N(C)C)C(C)C)c(C)s1 +CCCc1nnc(NC(=O)CCSc2ccccn2)s1 +Cc1c(Cl)ccc2sc(NC(=O)c3cnccn3)nc12 +Cc1ccc(F)c(NC(=O)C(C)OCC(C)C)c1 +c1cncc(COc2ccccc2CNc2ccc3c(c2)COC3)c1 +C#CCNC(=O)CNC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +CCC(C)(CC)NC(=O)CN(C)S(=O)(=O)c1cccnc1 +O=S(=O)(NCc1cccnc1)c1cc(F)ccc1F +COc1ccccc1NC(=O)COC(=O)Cc1cccs1 +CC(C)(C)c1nnc(NC(=O)N2CCN(c3ccccc3)CC2)s1 +O=C(CCCC(=O)N1CCOCC1)c1ccc(Cl)cc1 +CC(=O)Nc1ccc(Nc2ncnc3sccc23)cc1 +N#CCCN(C1CC1)S(=O)(=O)CC1CCCCC1 +COc1ccc(C(O)CNc2c(C)cccc2C)cc1Cl +CSc1nnc(CCC(=O)Nc2cc(Cl)ccc2Cl)o1 +CCN1C(=O)C(C(C)C)Oc2c(OC)cc(CO)cc21 +COc1ccc(OC)c(NC(=O)N2CCCCC2)c1 +CC(C)Cc1ncc2c(n1)CN(c1cc(OC(C)C)nc(N)n1)C2 +CS(=O)(=O)NCCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +Cc1ccc(C(=O)Cn2nnc3ccccc3c2=O)cc1 +Fc1cncc(C2NCCc3ccc4ccccc4c32)c1 +c1ccc(-n2nc(C3CC3)nc2-c2ccc(-n3cnnn3)cc2)nc1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCCc1ccccc1)O2 +Cn1cc(C(=O)NC2CCOc3c(Cl)cccc32)c(C(C)(C)C)n1 +CC(C(=O)NCCOc1cccc(Cl)c1Cl)n1ccnc1 +CCOC(=O)c1cnc(-c2cc(Cl)cc(Cl)c2)nc1 +CCCCN(C)C(=O)Nc1ccc(-c2csnn2)cc1 +Cc1noc(-c2ccc(C(=O)Nc3cnc(C(C)(C)C)nc3)cc2)n1 +CC(C)S(=O)(=O)N1CCC(NS(C)(=O)=O)CC1 +Cc1cc(-c2nc(CC(=O)NC3CCCC3)no2)n[nH]1 +CCCc1[nH]nc(C(=O)N(C)Cc2cscn2)c1N +CCn1nc(C)c(Cl)c1C(=O)Nc1ccc(C(=O)OC)cc1 +COC(=O)CCCC(=O)Oc1cccc(Cl)c1Cl +C#CCN(CC#C)C(=O)CCCc1ccc(O)cc1 +CC1CCN(C(=O)Cn2c(C3CC3)nc3ccccc32)CC1 +CN1CCc2ccc(NC(=O)N3CCCN(C(=O)C4CC4)CC3)cc21 +O=C(NCC1CCN(c2ccccc2F)C1)c1ccc2nccn2c1 +COc1ccc(OCCN2C3CCC2CC(=O)C3)cc1 +OCCn1ccnc1-c1ccccc1Br +COc1c(F)cc(NC(=O)Cc2ccc(F)cc2)cc1F +Cc1cccc(OCC(=O)NCC2(N3CCOCC3)CCCCC2)c1 +Cc1cc(SCC(=O)Nc2ccc(C(N)=O)cc2)nc(C(C)C)n1 +CC(CO)NC(=O)Nc1ccccc1OC(F)F +Cc1cc(C(=O)N2c3ccc(F)cc3CCC2C)no1 +COc1ccc(OC)c(CCC(=O)Nc2nc[nH]n2)c1 +COc1ccc(-c2nnc(SCC#N)n2Cc2ccco2)cc1 +Cc1ccc(C(=O)N(C)Cc2cccnc2)cc1N +COc1cccc(N2CCN(C(=O)c3cc(C)c(C)s3)CC2)c1 +Fc1cc(Cl)c2c(c1)CCNC2c1ccco1 +CS(=O)(=O)N1CCC(CNC(=O)Nc2ccccc2)CC1 +C=CCn1c(NCc2ccco2)cc(=O)n(C)c1=O +Cc1cc2ccccc2n1CC(=O)NC1CCC(C)CC1 +COc1ccc2[nH]cc(CC(=O)Nc3cccnc3)c2c1 +O=C1NCC2CN(Cc3ccc(F)c(-c4cccs4)c3)CCN12 +CCCC1CN(C(=O)Cc2c(C)nn(-c3ccccc3)c2C)CCO1 +Cc1cc(C)n(CCCNC(=O)C(C)Sc2ccccn2)n1 +Cc1ccc(CNCc2sc(C)nc2C)c(C)c1 +Cc1cc(F)ccc1NCC(=O)NC(C)(C#N)C(C)C +CCCC(=O)N1CCCC1C(=O)N(C)Cc1ccc(F)c(F)c1 +COc1ccc(C(=O)NCCCn2ccc3ccccc32)c(F)c1 +Nc1cc(=O)[nH]c(SCC(=O)Nc2ccc(Cl)cn2)n1 +CN1CCN(C(=O)CCc2nccs2)C(c2ccccc2)C1 +O=C(C1CCCC1)N1CCCC(c2nnc(-c3cccs3)o2)C1 +Cc1ccc(C(=O)NCc2c(C)cc(C)[nH]c2=O)cc1 +CC(=O)NC1CN(C(=O)CNS(C)(=O)=O)CC1c1ccccc1 +CCC(CO)NC(=O)c1nc(Cc2c[nH]c3ccccc23)no1 +CC(=O)NC(C(=O)N(C)Cc1cccc(Cl)c1Cl)C(C)C +Nc1ccc(C(=O)c2ccc3[nH]ncc3c2Cl)cc1 +CCc1noc(C)c1C(=O)N1CC(CC)C(N2CCOCC2)C1 +O=C(c1ncoc1-c1cccs1)N1CCOc2ccc(F)cc21 +CCC1CCCCN1c1ncnc(NCCCOC)c1N +Cc1cn2c(CN(C)C(=O)c3ccc(C#N)cc3C)c(C)nc2s1 +O=C(CCc1cccnc1)NC1(c2ccc(Br)cc2)CC1 +Cc1cccc(OC(=O)Cc2c(C)nc3cc(=O)[nH]n3c2C)c1C +O=C(NCCOc1cccc(Cl)c1)c1cccs1 +Cc1n[nH]c2ncc(C(=O)Nc3ccc(OC(F)F)c(F)c3)cc12 +COC1CCCC1OC(=O)c1nn(C(C)C)c(=O)c2ccccc12 +Cc1cc(C)nc(N2Cc3cnc(CC(C)C)nc3C2)n1 +O=C(NCCc1ccc(Cl)cc1)c1cnn2ncccc12 +CC(CCn1cccn1)NC(=O)c1cn(CC2CCCCC2)nn1 +CCc1nc(CN2CCN(c3nn4cc(C)nc4s3)CC2)cs1 +O=C1c2ccccc2CC12CCN(S(=O)(=O)c1cccs1)CC2 +CC(c1ccc(F)cc1)N(C)C(=O)COc1ccccc1O +CC(O)CN1CCN(C(=O)c2cc(Br)c[nH]2)CC1 +CCCNC(=O)C(C)Sc1nnc(-c2ccncc2)o1 +Nc1c(NCCC2=CCCCC2)ncnc1Nc1ccccn1 +O=C1CN(C(=O)c2ccccc2-c2ccccc2)CCN1 +Cc1ccc2nc(C)cc(C(=O)N3Cc4ccccc4C3)c2c1 +CN(C)c1nc(N)nc(COc2ccccc2C(N)=O)n1 +O=S(=O)(Oc1ccccc1F)c1cccnc1 +Cc1cc(OCC(=O)N(C)C)c2c3c(c(=O)oc2c1)CCCC3 +CC(C)(C)Cc1nc2cc(NC(=O)NCC(=O)NC3CC3)ccc2o1 +CC(C)(C)c1cccc(OCCn2ccc(N)n2)c1 +C=CCN1C(=O)CCC12CCCN(C(=O)NC(C)C)CC2 +COc1ccc(Cc2nnc(NC(=O)c3c[nH]c4ccccc34)o2)cc1 +CCn1c(C)cc(C(=O)N2CCC3(CCCN(CCO)C3=O)C2)c1C +COc1cccc(S(=O)(=O)CC(=O)Nc2ccc(C(C)C)cc2)c1 +Cc1ccc(NC(=O)Cc2nc(C)c(C(=O)NC3CC3)s2)cc1F +COc1ccc(CCOC(=O)c2ccc(O)cc2O)cc1 +CCC1CCCCN1C(=O)CCOCC1CCCO1 +CC(=O)c1cccc(OC(C)C(=O)NCCc2cccs2)c1 +CCS(=O)(=O)NCCOc1ccccc1C(C)(C)C +COc1ccccc1S(=O)(=O)NCC(C)(O)C1CC1 +COc1cc(C(=O)N(C)CCc2ccccn2)cc(OC)c1OC +COCCNC(=O)CN(C)c1cc(C)ccc1C#N +CC(NC(=O)c1ccc(F)cc1)c1cccc(NS(C)(=O)=O)c1 +CNS(=O)(=O)c1ccc2c(c1)N(CC(=O)c1cc(C)[nH]c1C)CC2 +NC(=O)NC1CCCN(C(=O)c2cccc(Cl)c2Cl)C1 +Nc1cc2c(cc1Oc1ccccc1)NC(=O)CO2 +CCOC(=O)c1ccc(SCc2ncc(C(C)C)o2)nc1 +CCn1nc(C(=O)N2CCN(CCOc3ccccc3)CC2)cc1C +Cc1cccc(C(=O)Nc2cc(Cl)ccc2F)c1N +C=CCNC(=O)c1ccc(NC(=O)NCc2cccc(F)c2)cc1 +CCc1onc(C)c1NC(=O)C1CC(=O)N(c2cn[nH]c2)C1 +COc1ccc(-c2ncc(N)cn2)cc1Br +Cc1cnc(N2CC3CC(C(=O)N4CCN(C)CC4)C(C2)O3)nc1 +CCC(C)NC(=O)CN1C(=O)C(C)Oc2ccccc21 +CCNC(=O)C(C)NC(=O)c1ccc(S(C)(=O)=O)cc1 +N#CCc1cc(C2CC2)n(-c2cccc(Cl)c2)n1 +COCc1nc(C(=O)Nc2cc(F)c(OC)c(F)c2)cs1 +COc1cc(C#N)cc(-c2cn[nH]c2-c2cccnc2)c1OC +Cc1nc(-c2cccc(CNC(=O)c3oc(C)nc3C)c2)n[nH]1 +Cn1cnc(CNC(=O)Nc2cc(F)c(Br)cc2F)n1 +Cc1ccn2cc(C(=O)NCCCN3CCOCC3)nc2c1 +C=CCNC(=O)c1ccccc1NC(=O)c1cnn(CC)c1 +CN1CC(C(=O)NCc2ccccc2OC(F)(F)F)CC1=O +CCNS(=O)(=O)c1ccc(N2CCOCC2)nc1 +Cc1nnc(Cn2c(=O)sc3ccccc32)n1C +COc1ccc(C)cc1NS(=O)c1ccc(N)cc1 +Cc1noc(C)c1C(C)NC(=O)Cc1csc(C(C)C)n1 +Nc1ccc(Cl)c(C(=O)NC2CCCCCC2)c1 +CC(C)Oc1cccc(C(=O)NCC(C)(C)c2ccncc2)n1 +O=C(NCCc1cc2ccccc2o1)c1ccc(-n2ccnn2)cc1 +COc1ccc(C(C)C)cc1Cc1ncc(N)cn1 +O=C(c1ccc(=O)n(-c2ccccc2)n1)N1CCCCC1 +CCCc1ccc(C(=O)CN2CCN(C(C)=O)CC2)cc1 +COCCOc1ncccc1NC(=O)N1CCC(c2ccccc2)C1 +CNC(=O)c1ccc(Cl)c(NC(=O)C2CCOc3ccccc32)c1 +COCc1ccc(C(=O)N2CC(Oc3ccccc3Cl)C2)o1 +Cc1cccc(C2(C(=O)Nc3ccccn3)CCC2)c1 +COc1ccc(OC(=O)c2cnc3[nH]c(C)nc3c2)cc1F +Cn1cnc(-c2nc(C(=O)NCCc3ccncc3)c3ccccn23)c1 +COc1ccccc1NC(=O)c1ccc(N(C)S(C)(=O)=O)cc1 +O=C(Nc1onc2c1CCCC2)c1ccc(Cl)cc1 +Cc1ccsc1CNC(=O)CSc1nnnn1C(C)C +NC(=O)c1ccccc1NC(=O)CN1CCCSc2ccccc21 +Cc1nc(C)c(C(=O)Nc2nc3c(s2)CCCCC3)s1 +O=C(NCc1cn(-c2ccccc2)nn1)c1n[nH]c2c1CCC2 +CCOC(=O)CNC(=O)c1cc(OC)ccc1N +N#Cc1ccnc(N2CC3CCC(C2)N(Cc2cscn2)C3=O)c1 +O=C(Nc1ccc2cn[nH]c2c1)c1ccccc1N1CCOCC1 +CC(=O)N1CCN(C(=O)c2ccc(S(=O)(=O)N(C)C)cc2)CC1 +O=C(NCCc1nnc2n1CCCCC2)c1ccc2[nH]cnc2c1 +CC(=O)N1CCc2cc(C(=O)N(C)Cc3cccc(C#N)c3)ccc21 +NS(=O)(=O)c1ccc(NC(=O)CC2CC3CCC2C3)cc1 +COc1c(F)ccc2c1C(c1cccnc1C)NCC2 +CCCC(=O)Nc1c(-c2cccs2)nc2ccccn12 +COc1cc(C(=O)NC(C)C#N)cc(OC)c1OC +CC(C)n1nc(C(=O)NCC(F)(F)F)c2ccccc2c1=O +Cc1cc(C(=O)Nc2cccn(C)c2=O)c2ccc(F)cc2n1 +COc1cc(CNc2ncnc3ccsc23)ccc1OC(F)F +COc1ccc(C(NC(=O)N2CCOCC2)C2CC2)cc1 +COc1cc2nc(-c3ccccc3)n(CC#N)c2cc1OC +Nc1cc(Cl)ccc1-c1nnc2ccccc2n1 +CCOC(=O)CC1C(=O)NCCN1Cc1c[nH]c2ccccc12 +CNC(=O)c1ccc(OC)c(NCC(=O)Nc2cc(C)nn2C)c1 +Cc1nc(CNc2cccc(Cl)c2F)oc1C +COc1cccc(CN(C)C(=O)CNc2cc(OC)ccc2F)c1 +CC(C)N(C)C(=O)CS(=O)(=O)c1ccc(Cl)cc1 +Cc1nc(SCc2ccc(F)cc2)[nH]c(=O)c1CC(=O)NC1CC1 +O=C(Nc1nccs1)C1CCN1S(=O)(=O)c1ccccc1 +Cc1ccc(NC(CO)Cc2ccccc2)cc1N +CCOCC(=O)N1CCOCC1c1csc(C)n1 +C#Cc1cccc(NC(=O)C2CCCN2c2nccs2)c1 +c1cnc(N2CCC3(CCN3c3ncccn3)C2)nc1 +CS(=O)(=O)N1CCCCC1C(=O)NCCCOC1CCCCC1 +O=C(Nc1cccc(OC(=O)C2CC2(Cl)Cl)c1)C1CC1 +O=C1OC(C(=O)NCc2ccc3ccccc3c2)Cc2ccccc21 +COC(=O)c1cc(NC(=O)CC2C=CCC2)c(F)cc1F +Cc1ccccc1SCC(=O)Nc1ccccc1C(N)=O +Cc1nn(CCc2ccc3c(c2)OCO3)c(C)c1N +O=C(CNC(=O)c1ccsc1)NCc1ccsc1 +Cc1occc1C(=O)Nc1cc(Cl)ccc1N +Cc1nc(CNc2nc(N)nc3c2nc(C)n3C)cs1 +Cc1cc2c(cc1S(=O)(=O)N(C)c1ccccc1)NC(=O)CO2 +O=C(COc1cccc(NC(=O)C2CC2)c1)Nc1cccc(F)c1F +COC1CCCC(OC(=O)c2cn(C)nc2C(C)(C)C)C1 +NC(C(=O)N1CCC(C(=O)c2ccccc2)CC1)c1ccccc1 +CC(=O)Nc1ccc(F)c(NC(=O)c2ccc(-n3ccnc3)nc2)c1 +COC(=O)Nc1cccc(NCc2sccc2C)c1 +COc1ccccc1OCC(=O)Nc1nc2c(s1)CCCC2 +Nc1ccc(Cl)c(NC(=O)Nc2ccc(F)cc2)c1 +CCN(CC(C)C#N)C(=O)c1ccc(S(C)=O)cc1 +CCOc1ncccc1-c1ccc(NC(C)=O)c2ncccc12 +CC1CN(C(=O)Cc2ccc[nH]2)CC(c2ccccc2)O1 +Cc1cc(C)c(NC(=O)c2csc(-c3ccsc3)n2)c(C)n1 +NC(=O)c1ccc(NCc2cccc(Br)c2)cc1 +Nc1nn(COc2ccc(Cl)cc2)cc1Cl +CCC(C)N1C(=O)c2ccccc2NC1c1ccccn1 +COc1ccc(-c2ccc3[nH]c(=O)oc3c2)cc1OC +COC(=O)C1=C(C)C(C(=O)COC(=O)c2ccsc2)=NC1C +CC(C)Oc1ccc(C(=O)N(C)CC(N)=O)cn1 +CCCc1nc(CNc2ccc(C(=O)NC(C)C)cc2C)cs1 +CC1Nc2ccc(NC(=O)c3ccc(=O)[nH]c3)cc2S1 +CC(C)(C(=O)N1CC(C(N)=O)C1)c1ccccc1F +CC(Oc1ccc(C#N)cc1)C(=O)NCC1Cc2ccccc2O1 +CC(Oc1cccc(Cl)c1)C(=O)N(CCO)Cc1ccccc1 +CCN1C(=O)CCc2cc(NS(=O)(=O)c3ccccc3)ccc21 +CCc1c(C(=O)NC(C)c2ccncc2)cnn1-c1ccc(F)cc1 +N#Cc1cccc(Sc2ncnc3[nH]ncc23)c1 +Cc1cc(C(=O)Nc2ccc(Br)cc2O)c(C)s1 +O=C(Nc1ccsc1)C1(c2ccc(F)cc2F)CCOCC1 +COC1CCN(C(=O)c2cnn(Cc3ccccc3)c2C(C)C)CC1 +CC(OC(=O)CNC(=O)CC(C)(C)C)c1ccc(F)c(F)c1 +CCc1cccc(C)c1NCc1cccc(C#N)c1 +CC(=O)Nc1ccc(NC(=O)C2CCCN(C(N)=O)C2)cc1Cl +Cc1cc(C(=O)NCc2nc(C)sc2C)n(C)n1 +Cc1cnn(CC(C)Nc2ncnc3[nH]ccc23)c1 +COc1ccc2cc(CN3CCCC(c4nncn4C)C3)ccc2c1 +CCC(Oc1ccc(F)cc1)C(=O)Nc1ncc(C)s1 +N#CC(C(=O)c1ccccc1)c1nnc2n1CCCCC2 +COc1ccccc1OCC#CCNC(=O)c1cc(C2CC2)on1 +CC(=O)N1CCC(NC(=O)CNc2ccccc2F)CC1 +Cc1ccc(SCC(=O)NCC(C)CN2CCOCC2)cc1 +COCCOc1ccc(C(=O)c2ccccc2OC)cc1 +Oc1ccc(O)c(Br)c1Br +CNC(=O)c1ccc(NC(=O)C(C)Oc2ccccc2)cc1 +Cc1ccnc(CC(C)N(C)C(=O)c2cccnc2C)c1 +Nc1cc(C(=O)OCC(=O)c2ccc3c(c2)OCCO3)ccc1Cl +CCOC(=O)NC(NC(=O)OCC)c1ccccn1 +CN(C)C(=O)c1nnc2sc(-c3ccc(Cl)cc3)nn12 +CN(Cc1ccc2c(c1)OCCO2)C(=O)c1ccc(F)cc1Cl +Cc1ccc(-n2c(C)cc3c(cnc4ncnn43)c2=O)cc1Cl +CC(=O)NC(C(=O)N(C)CC(=O)N(C)C)C1CCCC1 +Cc1ccc(CNC(=O)Cc2cn(C)c3ncccc23)o1 +CC(Oc1cccc(Cl)c1)C(=O)N1CCCS1(=O)=O +O=C(Nc1ccccc1C(=O)Nc1ccccn1)c1ccncc1 +CCN1CCN(C(=O)c2csc(NC(=O)CC(C)C)n2)CC1 +COc1ccc(CNC(=O)Nc2cccc(Cl)c2)cc1OC +CC1CCC(C)(NC(=O)C(C)NS(=O)(=O)c2cnn(C)c2)CC1 +Cc1cc(CNc2nnc(-c3ccc(S(C)(=O)=O)cc3)o2)c(C)o1 +Cc1ocnc1CNS(=O)(=O)c1cccc(C(=O)N(C)C)c1 +CC(C)C(=O)NC1CCCN(C(=O)c2sccc2OC(F)F)C1 +CCN(CC)C(=O)CN(C)C(=O)CNC(=O)c1cc(F)cc(F)c1 +CSc1nc(-c2ccccc2)nc2c1c(=O)n(C)c(=O)n2C +Cc1ccc(C(=O)NCC(=O)OCC(=O)c2cc(C)n(C)c2C)s1 +COC(=O)c1ccc(CSc2nc(=O)[nH]c3c2CCCC3)o1 +O=C(OCc1cc(-c2cc3ccccc3o2)on1)c1ccc(=O)oc1 +CCc1nc2n(n1)CCCC2NC(=O)c1ccc2c(c1)CCCC2 +COc1ccc(OCCN(C)C(=O)Nc2nc(C)cs2)cc1 +COc1ccccc1C(C)NC(=O)c1cc(-c2ccccc2)[nH]n1 +CC(Nc1ccc2c(c1)CCC2)C(=O)Nc1ccc(C(N)=O)cc1 +CC(O)CCNC(=O)C1Cc2cc(F)ccc2O1 +O=C(NCCC1CCCO1)c1ccc(Cl)cc1O +CN(Cc1ccc(-n2cccn2)cc1)C(=O)c1cccc2ccnn12 +Clc1cncc(OCC2COC3CN(c4cnccn4)CC23)c1 +CC(=O)Nc1cccc(NC(=O)COc2ccc(F)cc2C(C)=O)c1 +Cc1cc(C(=O)NCc2ccc(NC(=O)c3ccco3)cc2)on1 +CCC(=O)c1c(C)nn(Cc2ccccc2Cl)c1C +COc1ccc(-c2cc(-c3ccc(C)o3)[nH]c(=O)c2C#N)cc1 +CC(CO)NC(=O)c1sc(-c2ccco2)nc1-c1ccccc1 +COCc1nc2ccc(NC(=O)c3cc4ccccc4n3C)cc2[nH]1 +Fc1ccc(-c2noc(C3CCCO3)n2)c(Cl)c1 +CCN(CC)S(=O)(=O)c1cnc(NC)c(Cl)c1 +CCN(Cc1ccco1)C(=O)c1ccc2c(c1)OCC(=O)N2 +CC(C)COCCC(=O)Nc1ncc(C(N)=O)s1 +Cc1nc(-c2nnc(NC(=O)c3c(F)cccc3F)o2)cs1 +O=C(N1CCCC1)N1CCC2C(CCC(=O)N2CCCCO)C1 +CCOc1ccc(S(=O)(=O)Oc2ccccc2OC)cc1 +CNC(=O)C1CCN(C(=O)c2oc3c(c2C)C(=O)CC(C)(C)C3)CC1 +c1cnc(N2CC3(CCN(c4cnccn4)CC3)c3ccccc32)nc1 +Cc1nn(-c2ncccn2)c2c1C(c1ccc(O)cc1)CC(O)=N2 +COCCc1ccc(OC(=O)C2CCN(C(=O)C(C)(C)C)CC2)cc1 +CCn1cc2c(n1)C(COCC1CC1)CN(C(=O)c1cscn1)C2 +Cc1ccc2c(c1)N(CC(=O)c1cn(C)c3ccccc13)C(=O)CO2 +COC(=O)c1nonc1NCc1cccc(F)c1 +CCCNc1cccc(C(=O)N(C)C(C)C(C)C)n1 +CCN(CCOC)C(=O)c1ccc(C#CCO)s1 +Cc1c(C(=O)N2CCCC2c2ccc[nH]2)cnn1-c1ccccc1F +CCc1sc2ncc(N)n2c1-c1ccc2c(c1)OCCO2 +CCN(CC)C(=O)CNc1cc(NC(=O)C2CC2)ccc1C +Cc1cc(N)nn1CCCCOc1ccccc1Cl +COc1cc(C(C)=O)ccc1Oc1ncnc2oc(C)c(C)c12 +Clc1cc(Cl)cc(NCc2nc3n(n2)CCCCC3)c1 +CC(O)CN(Cc1nnc(-c2ccc(Cl)cc2)o1)c1ccccc1 +COCCN(Cc1ccccc1Cl)C(=O)c1ccn2nnnc2c1 +CCOC(=O)CSc1nc(C)cc(-c2ccco2)c1C#N +NC(=O)c1cnc(NC2CCC(O)CC2)c(Cl)c1 +CC(C)(C)OC(=O)N1CCC2(CC1)C(=O)Nc1ccccc12 +Cc1ccc(S(=O)(=O)NCc2ccnc(OC3CCC3)c2)s1 +O=C(Cc1ccc(F)cc1)OCC(=O)c1c[nH]c2ccccc12 +O=C(NCCc1cccs1)c1nccc2c1ncn2-c1ccccc1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)NCc1ccccc1 +Nc1ccc(Cl)c(NC(=O)c2ccc(F)cc2Br)c1 +CCCCOC(C)C(=O)Nc1cc(-c2ncco2)ccc1C +CC(C)C(O)C1NCCc2cccc(C(F)(F)F)c21 +CCOc1ccc(CCC(=O)N2CCC3OC(C)CC3C2)cc1 +Cc1cccc(CS(=O)(=O)NC(C)c2ccccc2)c1 +COCc1nnc(SCC(=O)Nc2ccc(C)cc2)n1N +O=S(=O)(Nc1cccc2c1CCCC2)c1ccc2c(c1)OCCO2 +Cn1cnc(CNS(=O)(=O)c2csc3ccc(Cl)cc23)n1 +Cc1cnc(N2CC3C(C2)C3NC(=O)C(C)C)nc1 +COc1ccccc1-n1nc(Cc2ccccc2)n(CC(N)=O)c1=O +O=C(C1CC(=O)N(c2ccccc2)C1)N1CCCC1 +COc1ccc(N(CC(=O)N2CCN(C)CC2)S(C)(=O)=O)cc1 +O=C(Cc1c(F)cccc1F)NCCCc1nnc2n1CCCCC2 +Nc1cc(CCCNC(=O)C2CCCO2)nn1-c1ccccc1 +CCC(C)(CO)NC(=O)Nc1cnc(-c2ccccc2)nc1 +COc1c(F)cc(NC(=O)Nc2cccc(C#N)c2)cc1F +COc1ccc(C(=O)N2CCC(Nc3cccnn3)CC2)c(F)c1 +CN(CCc1ccncc1)C(=O)Nc1ccccn1 +CC(NCC(=O)Nc1cccc(C(=O)N(C)C)c1)c1ccccc1 +CCCNC(=O)c1cccc(CNC(=O)N2CCOCC2)c1 +CC(=O)N1CCN(Cc2coc(-c3ccccc3)n2)CC1 +COc1ccc(C(C)(C)CNC(=O)NCc2ncn(C)n2)cc1 +COCCn1cc(NC(=O)NCc2cc3cc(F)ccc3s2)cn1 +CCC(C)OC(=O)C1=C(C)NC(=O)NC1c1ccccc1OC +Cc1ccccc1COC1CCN(C(=O)c2ccc(F)c(F)c2)CC1 +N#Cc1cccnc1-n1c(CCO)nc2cc(F)ccc21 +Cc1ccc(OCCNC(=O)NCc2nnc3n2CCCCC3)cc1 +CCc1ccc(C(=O)c2ccc(NC(=O)N3CCC(O)C3)cc2)o1 +CC(NC(=O)C(C)N1CCOCC1)c1ccccc1 +O=C(NCCOc1ccccc1Cl)NC1(CCO)CCC1 +Cc1ccc(N2CC(NC(=O)NCCOCCO)CC2=O)cc1C +COCC1(NC(=O)C2CC(=O)N(Cc3cccnc3)C2)CCCC1 +COC1CCN(C(=O)NCC(OC)c2cccc(Cl)c2)CC1 +CCc1nc(COc2c(C)cccc2C)sc1CO +CC1CCCN(C(=O)NCC(C(C)C)N2CCOCC2)CC1 +Nc1nc2cc(F)c(F)cc2n1CC(=O)NC1CCCC1 +COC(=O)c1sc2nc(C)nc(SC3CCOC3=O)c2c1C +CN(C)C(=O)CNc1ccc(S(C)(=O)=O)cc1S(C)(=O)=O +Cc1csc(C(NC(=O)NC(C)c2cnn(C(C)C)c2)C2CC2)n1 +CC(=O)N(C)Cc1cccc(NCC2CC3C=CC2C3)c1 +COCc1ccccc1C(=O)NCc1ccnc(OC(C)(C)C)c1 +CC(Cc1c(F)cccc1F)NC(=O)CCNC(N)=O +O=C(CCc1ccc2c(c1)OCO2)Nc1cnn(CC2CC2)c1 +Cc1ccc(C(C)c2nc(C)c(CCO)s2)cc1 +Cn1cnnc1-c1ccc(NC(=O)Cc2ccccc2Cl)cc1 +COc1cccc(NCc2ccc(O)c3ncccc23)c1 +CCc1nc(C(=O)Nc2ccc3c(ccn3CC(=O)N(C)C)c2)c[nH]1 +O=C(Nc1ncccc1OCc1ccncc1)c1ccccc1Cl +CC(C)c1nc(CN(C)Cc2ccc3ccccc3n2)cs1 +Cc1ccsc1C(=O)NC(c1ccc(F)cc1)c1nccn1C +CC(O)(c1cncc(F)c1)c1ccccc1Cl +Cc1cccc(CC(=O)N2Cc3cncnc3C2)c1 +CCCc1nnnn1Cc1cnn(-c2ccccc2)c1 +COCc1nc2cc(Cl)cnc2n1CCCO +CC(Nc1cc(-c2ccccc2F)nc2ccnn12)c1cnn(C)c1 +Cc1noc(C2CCN(C(=O)CNS(C)(=O)=O)CC2)n1 +O=c1ccc2ccc(OCc3noc(-c4cccs4)n3)cc2o1 +Cc1nnc(COc2ccc(NC(=O)Cc3c(C)noc3C)cc2)o1 +CCS(=O)(=O)c1nnnn1-c1ccccc1OC +CCCn1c(C)nnc1SCC(=O)c1cc(C)[nH]c1C +CCOC(=O)c1cc(-c2ccc(F)cc2)nn1-c1ccccn1 +Cc1cc(C(=O)N2CC3CCC(C2)N(Cc2cscn2)C3=O)no1 +Cc1nc(C2CCN(C(=O)NCCCc3c(C)noc3C)CC2)no1 +Cc1coc(-c2cc(NCC(C)(C)CCC#N)ccc2C)n1 +CN(CCn1cc(-c2ccc3ccccc3c2)nn1)S(C)(=O)=O +CC(C)n1c(C2CCCN(C(=O)CC(C)(C)C)C2)nn(C)c1=O +CCC(C(=O)Nc1nccs1)n1c(N)nnc1SC +CC(=O)Nc1nc(C)c(-c2nc(-c3ccccc3)no2)s1 +CC(CO)NC(=O)C(C)NC(=O)c1cccc(Cl)c1Cl +CS(=O)(=O)NC1=NCN(Cc2ccc3c(c2)OCCCO3)CN1 +COc1ccc(-c2ccc(O)cc2)c(OC)c1OC +COc1ccc(-n2nc3cc(C)c(NC(=O)C(C)C)cc3n2)cc1 +CN(C)c1cccc(C(=O)OCC(=O)N2CCCCCC2)c1 +CCCn1ncc(-c2cc(C)ccc2F)c(CO)c1=O +COc1ccc(CC(C)C(=O)Nc2ccnn2C(C)(C)C)cc1 +COCC(=O)NCC(OC)c1ccccc1OC +CCn1c(=O)n(CC(=O)Oc2ccc3cn[nH]c3c2)c2ccccc21 +CSc1ccc(C(=O)Nc2ccc3ncccc3c2)cc1 +CC1(CNC(=O)c2cccnc2OCC(F)F)CCCCC1O +C=CCOc1cccc(NC(=O)c2csc(-c3ncccn3)n2)c1 +N#Cc1ccc(Cl)cc1NC(=O)COc1ccc(F)c(F)c1 +CCC(CC1CCCCC1)C(=O)N1CCN(S(N)(=O)=O)CC1 +CCOC(C)C(=O)N1CCN(C(=O)c2c(F)cccc2Cl)CC1 +Cc1n[nH]c(C)c1CCOC(=O)CC(C)c1ccccc1F +CCNC(=O)NCc1cccc(NC(=O)C(C)CC)c1 +CCOc1ccccc1OCc1nc(CC)c(CC#N)s1 +CC(=O)N1CCC(NC(=O)NCc2ccnc(OC3CCC3)c2)C1 +c1ccc(CCCNc2ncnc3[nH]ncc23)cc1 +CCOC(=O)C1=C(C)C(C(=O)N2CCn3cccc3C2C)=NC1C +O=C(OC1CCCCC1=O)c1csc(-c2ccccc2)n1 +COCC(=O)N1CC(c2cc(Nc3cnccn3)nc(C)n2)C1 +CCCCc1nnc(NC(=O)CN2CCc3cc(F)ccc3C2)s1 +Cc1nc(CNc2nncc(-c3ccc(Cl)cc3)n2)cs1 +CC(=O)Nc1ccc(S(=O)(=O)NC2Cc3ccccc3C2)cc1 +CCCc1ncc(C(=O)Nc2cc(C)ccn2)c(N)n1 +CC(C)N1CC(C(=O)Nc2ccccc2-n2cnnn2)CC1=O +CCC1CN(c2ccc(S(N)(=O)=O)cc2N)CCO1 +N#Cc1c(F)cccc1NCCNC(=O)c1ccc[nH]c1=O +Cc1cnn(Cc2cc(C(=O)NCC(C)(C)c3ccncc3)no2)c1 +CC(=O)c1cccc(OS(=O)(=O)c2ccc3c(c2)CCC3)c1 +COc1c(F)cc(NC(=O)Cn2cnc3c(cnn3C)c2=O)cc1F +CCC(C(=O)N1CCN(Cc2cccs2)CC1)n1cccn1 +N#Cc1cccc(NC(=O)C(O)c2ccc(F)cc2)c1 +Cn1nc(-c2cccnc2)c2c1CN(C(=O)c1ccccc1)CCC2 +CCOc1ccccc1CC1(c2ccccc2)NC(N)=NC1=O +CN1CCOC(C)(C(=O)NCCc2cccs2)C1 +O=c1c2cc(Cl)ccc2ncn1Cc1nnc(-c2cccs2)o1 +CC1CCc2nc(CN(C)CCN3CCOCC3)sc2C1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)N(C)Cc1cccnc1 +Cc1[nH]ncc1S(=O)(=O)N(CCC#N)C1CC1 +CN1CCN(C(=O)Cn2c(=O)oc3ccccc32)CC1 +Cc1cccc(-c2nnc(COC(=O)c3scnc3C3CC3)o2)c1 +CNC(=O)c1cccc(OC(=O)C2CCCN2C(=O)C2CC2)c1 +Cc1cc(C(C)NC(=O)NCCNC(=O)C2CC2)c(C)s1 +COc1ccc(-n2cc(CNC(=O)c3cc(C)n[nH]3)nn2)cc1 +COc1ccc(C)cc1C(O)CNC(=O)C1CCCCC1 +Nc1ccc2c(c1)nc(C(F)(F)F)n2C1CCCCC1 +O=C(NC1CC1)c1ccccc1NS(=O)(=O)c1cccc(F)c1 +O=C(c1cn(CC2CCCCC2)nn1)N1CCCC(O)C1 +c1ccc(-c2nc(CSc3ccccn3)no2)cc1 +COCC(C)Nc1ncnc2scc(-c3ccc(OC)cc3)c12 +Cc1cc2c(=O)n(Cc3ccccc3C#N)cnc2s1 +CN(Cc1cccc(Cl)c1)C(=O)C1CCOCC1 +COc1ccc2nc(C(=O)OCC3CCCCO3)ccc2c1 +CCCn1nc(C(=O)N2CCCCC2)cc1-c1ccco1 +CNC(=O)c1ccc(NC(=O)CCC2CCCO2)cc1Cl +CS(=O)(=O)N1CCc2cc(C(=O)NCc3ccc(F)cc3)ccc21 +CCCc1nnc2sc(NC(=O)c3cccs3)nn12 +Cn1cc(CCNc2ncnc3c2cnn3-c2ccccc2)cn1 +CCOc1ccccc1-c1nnc(SCC(=O)NC(C)(C)C)o1 +C=CCn1c(SCc2noc(C)n2)nnc1-c1ccc(OC)cc1 +CCC1CCC(NC(=O)Cn2c(C)c(C)sc2=O)CC1 +CCc1nc(CNc2cccc(Oc3ccccn3)c2)cs1 +CN(C)c1nc(Cn2cnc3sccc3c2=O)ns1 +Cn1cc(C(=O)OCCC2CCCO2)c(C(C)(C)C)n1 +COC(=O)c1cc(CSc2nc(-c3cccs3)n[nH]2)oc1C +COCCNC(=O)Nc1ccc(OCc2ccccc2F)cc1 +Cc1onc(-c2ccc(F)cc2)c1C(=O)NCCCN1CCCC1=O +CC1CCCN(C(=O)CCc2nc(N)nc(Nc3ccccc3)n2)C1 +COC(=O)N(C)c1ccc(NC(=O)CCc2cccnc2)cc1 +O=C(NCCC1=CCCCC1)c1nnc(Cc2ccc(F)cc2)o1 +CC(C(=O)NCC(=O)Nc1ccc(-n2cccn2)cc1)c1ccccc1 +CCN(CC1CC1)C(=O)NCCc1nnc2n1CCCCC2 +O=C(OCC(=O)N1CCCC1)c1ccc(-n2cccn2)cc1 +COCCN(CC(C)C)S(=O)(=O)c1ccccc1 +NC(=O)Cc1csc(NC(=O)c2ccccc2C(F)(F)F)n1 +Cc1csc(SCC(=O)Nc2ccccc2C(N)=O)n1 +COc1ccc(OC)c(NCC(=O)c2ccc(F)cc2)c1 +Cc1cc(NC(=O)NC(C)(CO)C2CC2)ccc1OCC(F)(F)F +c1ccc(COC2CN(Cc3ccoc3)C3CCCOC23)nc1 +COc1ccccc1N(Cc1cc2ccc(C)cc2[nH]c1=O)C(C)=O +O=C(CNc1ccc(Br)cc1)NCC1CC1 +COc1ccc(OC)c(NC(=O)c2ccc(O)cc2)c1 +CC(C)C(=O)Nc1nnc(COc2ccccc2F)s1 +Cc1cccc(C(C)C)c1NC(=O)Cn1ncc(=O)c2ccccc21 +CCN(C1CCCC1)S(=O)(=O)c1ccccc1N +CC1(C(N)=O)CN(C(=O)CCOc2ccccc2)CCO1 +Cc1[nH]nc(-c2cccs2)c1NC(=O)OCc1ccccc1 +CC(C)NC(=O)c1ccc(NC(=O)c2ccc(OC(C)C)cc2)cc1 +CCc1noc(C2(NC(=O)c3ccoc3)CCCCC2)n1 +Cc1ccc(-c2cc(O)c3c(c2)CN(C(=O)C2(C)CC2)CCO3)s1 +C=CCOC(=O)c1sc(-c2ccc(OC)c(OC)c2)nc1C +O=C(Cc1cccc(F)c1F)NCC1Cc2ccccc2O1 +Cc1noc(C)c1C(=O)N1CCC(Oc2ccccc2)CC1 +Cc1cnc(CNC(=O)c2cc(Cl)ccc2Cl)o1 +CC(C)OCCC(=O)N(C)CC(=O)N1CCOCC1 +CCCNC(=O)c1nc(-c2ccccc2)n(-c2ccc(C)cc2)n1 +COCCNC(=O)Cc1csc(-c2ncccn2)n1 +CC(C)CN(CC(C)C)C(=O)c1ccc(Cl)c(S(N)(=O)=O)c1 +N#Cc1cccc(C(=O)Nc2ccc(C#N)c(Cl)c2)c1 +Cc1nc(C)c(C(=O)NCc2cccc(Cn3ccnc3)c2)s1 +CCN(C(=O)CCC(C)C)c1ccc(F)c(F)c1 +C=C(C)Cn1cnc2c(oc3nc(-c4ccco4)c4c(c32)CCC4)c1=O +CC(c1nc(N)nc(N(C)C)n1)N(C)Cc1nc2ccccc2s1 +Cn1nnnc1-c1cccc(NC(=O)c2cccc(-c3ccoc3)c2)c1 +Cc1c2c(nc3cc4c(cc13)OCO4)-c1ccccc1S(=O)(=O)C2 +CCn1nnc2cc(C(=O)N3CCCC3Cn3cc(C)cn3)ccc21 +Cc1ccc(-c2cc(C(=O)Nc3ccncc3)no2)cc1F +Cc1noc(CNc2ccc(Cl)c(Br)c2)n1 +CC(=O)NCCNc1ncc(N)cc1Br +COc1ccc(C(=O)NCc2cccnc2)cc1C +CC1CCC(NC(=O)Nc2ccc(-n3cccn3)nc2)CC1 +CC(C)(C)c1noc(CCC(=O)Nc2ccc3c(c2)OCC(=O)N3)n1 +CCCC1CN(C(=O)Nc2cc(OC)ccc2F)CCO1 +COc1cc(N)ccc1NC(=O)Cc1ccccc1Cl +Cc1nn(CC(=O)NCc2ccc(F)cc2)c(C)c1Br +CCCCn1c(N)c(N(C)CCc2ccccc2)c(=O)[nH]c1=O +COC(=O)CC1Sc2ccc(C)cc2NC1=O +COc1cccc(-c2ccnc3c(C(=O)NC(C)C)cnn23)c1 +CCOCC(=O)NC(C)(C)c1nc(C)c(C)s1 +c1ccc(-n2nnnc2N2CCCC(c3nc4ccccc4[nH]3)C2)cc1 +CSc1ccc(C)c(C(=O)Nc2nncn2Cc2ccccc2)c1 +O=C(NCCc1c[nH]c2ccccc12)c1cccc(-n2cnnn2)c1 +CNC(=O)COc1ccccc1CN1CCC(CN2CCOCC2)C1 +CCCNC(=O)c1cccc(C(=O)N2CCCCCC2)c1 +O=C(c1ccc(COc2ccc(F)cc2)o1)n1cccn1 +CC(C)CCNC(=O)Cn1cnc2sccc2c1=O +CC(=O)c1ccc(NC(=O)CCCNC(=O)c2ccco2)cc1C +CC(NC(=O)c1ccccc1S(C)(=O)=O)c1nc2ccccc2[nH]1 +Cc1csc(C(C#N)C(=O)CCOCC(C)C)n1 +O=C1NCCN1c1nc(CC(=O)N2CCOCC2C2CC2)cs1 +Cc1cc(C2CCCN2C(=O)Cc2csc(C(C)C)n2)on1 +CC(C)(C)c1n[nH]c(SCC(=O)NC2CCCCC2)n1 +O=c1ccc(-c2cccc(NS(=O)(=O)c3ccc(F)cc3)c2)n[nH]1 +O=C(NC1CCCc2occc21)c1ccnc(F)c1 +C=CCN(SC)S(=O)(=O)c1ccc(C)cc1 +CN(C)c1ccc(NC(=O)Cn2ccccc2=O)nc1 +Cc1ccc(NC(=O)c2ccc(OCC(F)F)nc2)cc1C(N)=O +CC(=O)N1CCC(C(=O)c2ccc(C)cc2C)CC1 +CCn1nc(C)c(S(=O)(=O)NCc2ccc(C)o2)c1C +Cn1cc(NC(=O)C2CCCN(C(=O)c3ccco3)C2)cn1 +Cc1ccccc1NC(=O)CCc1ccc2nc[nH]c2c1 +COc1ccc(OC)c(CNC(=O)c2ccccc2Cl)c1 +CC1(O)CCN(C(=O)c2cccc(-n3cnnc3)c2)CC1O +COc1cc(C(=O)NCc2ccccc2Cl)ccc1OC(F)F +COc1ccc(C(=O)NC(C)c2ccc(OC)c(OC)c2)cc1F +C=C(C)COc1cccc(NC(=O)c2ccc(C(=O)N(C)C)cc2)c1 +CCCNS(=O)(=O)c1cn(C)c(=O)n(C)c1=O +Cc1nc(NC(=O)c2ccc3c(c2)CCC3)sc1-c1ccccn1 +CCOCCCNC(=O)N1CCc2cc(F)ccc2C1 +CCOc1ccc(CCn2nc(C)c(N)c2C)cc1F +COC(=O)CCC(=O)c1ccc(Cl)c(Cl)c1Cl +Cc1cc(NC(=O)C2CCCC2)n(-c2nc3ccccc3[nH]2)n1 +Cc1cc(C)n(CC(=O)N2CCc3ccccc3C2)n1 +CC(C)(C)c1nnc(SCCOc2ccc(F)cc2)n1N +CCCSc1nc2nc3c(cn2n1)C(=O)CC(c1cccs1)C3 +COc1ccccc1SCC(O)CN1CCOCC1 +CC1Oc2ccccc2N(CCC(=O)N(C)c2ccccc2)C1=O +Cn1cc(CCOC(=O)c2c(F)cc(F)cc2F)cn1 +Clc1cc(Cl)c2c(c1)NCc1scnc1-2 +O=C(NCc1ccc(F)cc1)C(c1ccccc1)n1cnnn1 +Cc1coc(-c2cccc(NC(=O)N(C)CC(O)C(F)(F)F)c2)n1 +O=C(NCc1nnc2n1CCCC2)Nc1ccncc1 +CC(=O)NC1CCCN(C(=O)Nc2cccc(-n3nnnc3C)c2)C1 +Cc1csc(C(O)(CC(=O)NC2CCCC2)C(F)(F)F)n1 +Cc1nn(C)c2c1C(c1cc(F)ccc1F)CC(=O)N2 +c1ccc2c(NCCN3CCOCC3)nc(-c3ccsc3)nc2c1 +COCC(=O)N1CCC2OCCC2(COCc2ccncc2)C1 +Cc1nc(-c2nnc(NC(=O)CCn3ccc(=O)[nH]c3=O)o2)cs1 +CCC(C)(CNS(C)(=O)=O)N1CCOCC1 +Cc1nc2ccc(NC(=O)C3CC(=O)N(C)C3)cc2o1 +O=C(NCC1CC1)c1nnc2ccc(Cl)cc2n1 +CSc1ncc(C(N)=O)c(NCc2ccccc2)n1 +NC(=O)NCC(=O)NCC(c1ccc(F)cc1)N1CCOCC1 +COc1ccccc1NC(=O)N1CCc2ccc(N)cc21 +Cn1ncc2c(=O)n(CCC(=O)Nc3cnc4ccccc4c3)cnc21 +CCOC(=O)CCC(C)NC(=O)c1ccc(F)c(F)c1 +CCOCCNC(=O)COc1ccc2c(c1)CCC2 +Cc1cc(C(=O)NCC(C)c2ccccc2)c2c(C)nn(C)c2n1 +COc1ccc2c(C)c(CCC(=O)Nc3cc(C)on3)c(=O)oc2c1 +CCOc1ccccc1NS(=O)(=O)c1cccc(N)c1 +Cc1noc(CCNC(=O)NC(C)c2ccc(F)cc2Cl)n1 +Cc1ccccc1CC(=O)Oc1cccc(N2CCCC2=O)c1 +COc1ccccc1C(C)NC(=O)CS(=O)(=O)c1ccccc1 +Cc1ccc(-c2cn[nH]c2C2CCCN(c3cc(N)ncn3)C2)cc1 +CCC1CN(C(=O)Nc2ccc(OC)cc2)CCO1 +O=C(NCc1ccccc1CO)C1CCN(CC(F)(F)F)CC1 +Cc1csc(=O)n1CC(=O)N(CC1CCCCC1)C1CC1 +CCN(C(=O)COc1cccc(NC(=O)OC)c1)C1CCCCC1 +CC1C(=O)N(c2ccc(F)cc2)CCN1S(=O)(=O)c1ccccc1 +COc1ccc(F)cc1S(=O)(=O)Nc1ccc(NC(C)=O)cc1 +COc1ccc(OC)c(C(=O)C(C#N)c2nc3ccccc3n2C)c1 +Cn1cc(C(=O)N2CCC(n3ccnn3)CC2)c(C(C)(C)C)n1 +Cc1ccc(Br)c(NC(=O)Cn2nnnc2C(C)C)c1 +CCOc1ncccc1CNCc1csc(CC)n1 +CSc1nc(N)c2c(C(N)=O)cc(=O)[nH]c2n1 +NC(c1c(F)cc(Br)cc1F)C(F)(F)F +COCCOCC1NCCc2c(O)cc(OC)cc21 +Cc1ccc(S(=O)(=O)N(C)CCOCC2CC2)cc1F +Cc1nn(C)c(C)c1-c1cc(C(=O)N(C)Cc2ccc(C#N)cc2)[nH]n1 +CC(C)CC(C)N(C)C(=O)c1ccc(Cl)c(N)c1 +Cn1c(=O)cc(N2CCN(C(=O)c3ccco3)CC2)[nH]c1=O +Cc1ccccc1C(C(=O)NC1(CO)CCCCCC1)N(C)C +O=S(=O)(NCC#CCOc1cccnc1)c1ccc(F)cc1F +O=C(Cn1cnc2cc3c(cc21)OCCCO3)NC1CCCCC1 +COc1cccc(C(=O)NCc2ncc(-c3ccccc3)o2)c1O +CCOc1cccc(C(=O)Nc2ccc(NC(=O)CC)cc2)c1 +Cc1ccc(CNC(=O)CN(C)c2ncnc3[nH]cnc23)cc1F +Fc1ccc2nc(C(F)(F)F)n(C3CC3)c2c1F +Cc1occc1C(=O)NC(CC(C)C)c1ccccc1 +O=C(CNC1=NS(=O)(=O)c2ccccc21)Nc1ccccc1F +Cc1cccc(NC(=O)c2cccnc2Oc2ccccc2)n1 +O=C(Oc1ccccc1F)C1(c2ccccc2)CC1 +COC(=O)C(C)NC(=O)C1CC(=O)N(C2CCCCCC2)C1 +O=C(Nc1ccc2oc(-c3cccnc3)nc2c1)c1ccco1 +CCOc1ccc(Cc2c(O)nc3n(c2=O)CCS3)cc1 +Cc1cc(C)c2nc(NC(=O)c3snnc3C)sc2c1 +O=C(COC(=O)c1ccncc1)Nc1cc(Cl)ccc1Cl +O=C(CC1C=CCC1)Nc1cccc(-c2cnco2)c1 +NC(=O)CC1CCCCN1C(=O)c1cc(=O)[nH]c2ccc(Cl)cc12 +N#Cc1ccc(NC2CCN(CC(F)F)CC2)c(F)c1 +Cc1ccc(CC(=O)Nc2onc3c2CCC3)c(C)c1 +CN(CC12CC3CC(CC(C3)C1)C2)C(=O)CCn1cncn1 +O=C(Nc1ccc(-n2cccn2)cc1)c1n[nH]cc1Cl +CCc1ccc(OC(=O)c2cc(C(N)=O)cs2)cc1 +COc1ccc2c(c1OC)CCNC2c1cccc(C)n1 +C=CCNC(=O)c1cnc(-c2ccccc2Cl)nc1N +CCc1noc(CC)c1CNC(=O)c1ccc2c(c1)CCN2C(C)=O +CC1CCN(C(=O)CC2Oc3ccccc3NC2=O)CC1 +CCNc1cc(NCCNC(=O)Nc2ccccc2C)nc(C)n1 +CCN(CC(=O)NC(C)(C)C)C(=O)NCc1cccc(F)c1 +Cc1ccn2c(C(=O)N3CCC4(CCOCC4)CC3)c(C)nc2c1 +Cc1cc(OCC(=O)Nc2nc3c(s2)CN(C)CC3)no1 +CCOc1ccc(F)c(C(=O)N2CCC(C)CC2)c1F +O=C(Nc1ccc(CN2CCCC2=O)cc1)c1ccc(F)nc1 +Cc1ccc(N2CC(C(=O)N(C3CC3)C(C)C3CC3)CC2=O)cc1 +CC(=O)Nc1ccc(F)c(NC(=O)C2CCC(=O)N2)c1 +Fc1ccc(Cc2nnc3sc(C4CCC4)nn23)cc1 +CC(=O)N1CCC(N(C(=O)c2cncc(F)c2)c2ccccc2)CC1 +CS(=O)(=O)N1CCN(c2cnc3ccccc3n2)CC1 +Cc1cc(C)c(CNC(=O)c2c[nH]c3ncccc23)c(=O)[nH]1 +Cc1sc2nc(CCn3c(=O)oc4ccccc43)[nH]c(=O)c2c1C +O=C(Cn1nc(-c2ccccc2)ccc1=O)Nc1nc(C2CC2)n[nH]1 +O=C1CCCc2c1c(-c1cccnc1)nn2C1CCCCC1 +CCOC(=O)N1CCN(Cc2nc3ccccc3c(=O)[nH]2)CC1 +CCCNC(=O)c1nn(-c2ccccc2)c(=O)n(CC)c1=O +CC(=O)Nc1cc(NC(=O)c2csnn2)ccc1F +COc1ccc(COC(=O)c2c(NC(C)=O)sc(C)c2C)cc1 +C=CCn1c(N)nnc1SCC(=O)Nc1c(C)cc(C)cc1C +Nc1cc(S(=O)(=O)Nc2ccc(Cl)cc2)ccc1Cl +COC(=O)N1CCC(NC(=O)CC2CC3CCC2C3)CC1 +CC(=O)Nc1ccc(C(=O)OCC2CCC(=O)N2)cc1 +CCOc1cc(OCC2CCCN(C(=O)OC(C)(C)C)C2)ncn1 +Cc1ccc(S(=O)(=O)N(C)Cc2csc(C)n2)c(C)c1 +CCOC(C)C(=O)Nc1ccn(-c2ncccc2Cl)n1 +Cc1ccccc1OCCN1C(=O)CNC(=O)c2ccccc21 +CCc1ccc(C(=O)NCCOc2ccccc2C)o1 +Cc1nn(C)c(C)c1OS(=O)(=O)c1ccc(N2CCCC2=O)cc1 +CCN(CC)c1ccc(NC(=O)Cc2c(C)noc2C)cn1 +Cc1cccc(C)c1NCCc1nc(C)c(C)s1 +COC(=O)c1ccc(NC(=O)c2cccc(F)c2N)cc1 +Cc1cc(=O)n(C)cc1NC(=O)CCCC(=O)c1ccc(F)cc1 +Cc1nn(Cc2ccccc2)c(C)c1CNC(=O)c1cccc(C#N)c1 +Cc1ncncc1C(=O)NCCc1nc(-c2ccccc2)cs1 +CC#CCN1CC=C(c2cnn(-c3ccccc3)c2)CC1 +CCOC(=O)C1CCCN(C(=O)CN2C(=O)COc3ccccc32)C1 +CC(C)C(=O)c1ccccc1NC(=O)C1CC1c1ccco1 +O=C(NCC1CC1)c1c[nH]nc1-c1ccc(F)cc1 +CC1CCCC(OCC(=O)Nc2cccc(CO)c2)C1 +N#Cc1ccccc1OCC(=O)Nc1ccc(Cl)cc1 +Cn1cc(CNC(=O)Nc2ccc3c(c2)NC(=O)CS3)cn1 +Nc1c(NCc2ccc(Cl)cc2)ncnc1NC1CCCC1 +CC(NC(=O)c1cccc(C#N)c1)c1nncn1C +CN(C)C(=O)C1CCCN(C(=O)C2CCCN2S(C)(=O)=O)C1 +O=C(CCC(=O)c1cccs1)NCC1CCCc2ccccc21 +COc1ccc(-c2cc3c(=O)n(CC(=O)NC(C)C)ccn3n2)cc1 +c1ccc(-n2ccc(COc3ccccc3-n3ccnc3)n2)cc1 +O=C(NCCc1cccnc1)N(CCO)C1CCCc2ccccc21 +CCNC(=O)C1CN(C(=O)c2cccs2)CC12CCCCC2 +CC(C)c1nc2ccccc2c(=O)n1CC(=O)NC1CCCCC1 +COc1ccc(OCCCNC(=O)c2ccc(=O)n(C)n2)cc1 +CCCn1nc(C)cc1NS(=O)(=O)c1ccc(OC)c(OC)c1 +O=C(N1CCOCC1)N1CCCC(S(=O)(=O)N2CCOCC2)C1 +N#CC(C(=O)CCc1cscn1)c1nc2cc(Cl)ccc2s1 +CC(C)(C)c1nc2sc(-c3cccnc3)nn2c1C#N +Cc1ncc(CNC(=O)N2CCN(c3ccccc3)CC2)s1 +COCC(=O)NC(C(=O)NC(C)c1nc2ccccc2[nH]1)C(C)C +COCc1cc(C(=O)Nc2ccc3oc(=O)n(C)c3c2)ccc1F +Cc1ccc(NCC(=O)Nc2cccc(C(=O)NC(C)C)c2)cc1 +CCCOC(=O)c1cnn(-c2ccc(OC)nn2)c1C(F)(F)F +COc1ccc(C(=O)OCn2nnc3ccccc3c2=O)cc1OC +Cc1sc(-c2noc(C3CC3)n2)cc1NC(=O)C1CC1 +CCCn1ccnc1-c1cccc(NC2CCN(C(N)=O)CC2)c1 +Cc1nn(C)cc1S(=O)(=O)NCCNC(=O)c1ccccn1 +CCCCN(CC(N)=O)C(=O)c1cccc(-n2cccc2)c1 +CCN(CC(N)=O)S(=O)(=O)c1ccc(OC)cc1 +CN(CC1CCCCO1)S(=O)(=O)c1cc(Cl)ccc1Cl +CC1CCC(C(=O)N2CC(=O)NC3CCCCC32)O1 +CCNc1nc(-c2cnn(C)c2)nc(C)c1C(C)C +CC1CCCC(NC(=O)Nc2cccc(N3CCOC3=O)c2)C1 +O=C1CCCN1c1ccc(C(=O)N2CCOCC2C2CC2)cc1 +Cc1cc(C(=O)NC(C#N)c2cccc(Cl)c2)nn1C(C)(C)C +Cc1cnc2n(c1=O)C(CC(=O)NC1CCCCCC1)CS2 +CCC(=O)N(CC)Cc1cc2cc(OC)ccc2[nH]c1=O +CC(C)CNC(=O)CNc1ccc(C#N)c(Cl)c1 +CCN(CCO)C(=O)c1ccc(C)c(NC(C)=O)c1 +CC(=O)N1CCC(C(=O)Nc2cc(-c3ncco3)ccc2C)C1 +Cc1ccc(NC(=O)N2CCNC(=O)C2)cc1C(F)(F)F +Cc1nnc2ccc(C(=O)NCC(O)c3ccc4ccccc4c3)cn12 +FC(F)(F)c1ccc(Cn2ccnc2-c2ccc3nonc3c2)cn1 +O=C(NCCCCN1CCOCC1)c1cccc(-c2ccoc2)c1 +N#Cc1c(N2CCCC2)n[nH]c1NC(=O)COc1ccc(Cl)cc1 +COc1ccc(NC(=O)Cc2ccc[nH]2)cc1N1CCOC1=O +O=C(Nc1ccc(N2CCCC2)nc1)c1cn2cccnc2n1 +COc1ccc(C(CO)N(C)C(=O)Nc2cc(F)cc(F)c2)cc1 +CC(C)n1cc(C#N)c(NC(=O)C2CCC(F)(F)CC2)n1 +CCC(C)NC(=O)c1cccn(-c2ccc(NC(C)=O)cc2)c1=O +CCCc1nnc(NC(=O)N(C)Cc2cc(Cl)cn2C)s1 +CN(Cc1cnn(C)c1)C(=O)c1csc2c1CCCC2 +NC(=O)c1cncc(OCc2cccc(C(F)(F)F)c2)n1 +O=c1[nH]c2ccccc2nc1Cn1cnc2sccc2c1=O +O=C(Nc1nncs1)C1CC=CCC1c1nc2ccccc2s1 +Cc1nc2ccc(NS(=O)(=O)c3ccc(F)c(Cl)c3)cc2o1 +CCn1cc(S(=O)(=O)N2CCCC2c2ccc(C)o2)cn1 +Cc1ccn2c(=O)c(C(=O)Nc3ccc(CC(N)=O)cc3)cnc2c1 +Cc1cc(=O)[nH]c(-n2[nH]c(C)c(Cc3ccccc3)c2=O)n1 +CC1CCCCN1C(=O)CCc1nc2ccccc2o1 +C=C(C)Cn1nnc(CO)c1COc1cccc(CC)c1 +CN(CCOCC1CC1)S(=O)(=O)c1cc(Cl)ccc1Cl +CCSc1nncn1-c1cccc(NC(C)=O)c1 +Cn1cc(C(=O)Nc2n[nH]c(Cc3ccc(F)cc3)n2)ccc1=O +CCOC(=O)Cc1csc(-c2ccc(OC)c(OC)c2)n1 +Cn1ccnc(NC(=O)C2CC2c2cc(F)ccc2F)c1=O +CCC(C)n1nccc1NC(=O)c1ccncc1F +CCOC(=O)c1sc(NC(=O)c2cc(C)oc2C)c(C#N)c1C +O=C(Nc1cccc(OCc2ccccn2)c1)c1ccccc1 +NC(=O)NCCCCCC(=O)N1CCN(c2ccccc2)CC1 +CC(C)c1nc(Cn2cc(Br)cn2)cs1 +Cc1cc(N2CCC(Nc3cccnc3)CC2)nc(-c2ccncc2)n1 +C=CCc1cc(CN2CCOC(c3cccs3)C2)cc(OC)c1O +CC1(C)OC(=O)CC1C(=O)NCCCCCc1nc2ccccc2[nH]1 +CC(C)NC(=O)CCN1CCc2[nH]nc(-c3ccc(F)c(F)c3)c2C1 +CCC1CCCN(C(=O)CNC(=O)c2cccs2)C1 +COC(=O)C1(c2ccc(Cl)c(Cl)c2)CCC(=O)CC1 +CCC(=O)Nc1ccc(O)c(C(=O)N2CCc3ccc(F)cc3C2)c1 +Cc1cccc(NC(=O)C2CC(=O)N(C)C2)c1C(=O)N1CCCC1 +COc1cc2nc3[nH]c(NCc4ccccc4F)nn3c2cc1OC +O=C(c1ccccn1)N1CC(OCC2CCCC2)C2OCCCC21 +Cn1nc(CC(C)(C)C)cc1NC(=O)c1ccc(F)nc1 +COc1ccc(CCNC(=O)CNC(N)=O)c(OC)c1 +CCSc1nsc(NC(=O)Nc2ccc(F)cc2)n1 +CCCN(CC(=O)OC)S(=O)(=O)c1ccc(F)cc1 +Nc1nnc2c(n1)[nH]c1ccc(S(=O)(=O)N3CCCCC3)cc12 +CC(C#N)OC(=O)c1ccc2c(=O)n3c(nc2c1)CCC3 +Cc1ccc(C(=O)CCC(=O)NC(C)C(N)=O)cc1 +CCCC(C)Nc1nc2c(c(=O)[nH]c(=O)n2C)n1C +Cc1nc(OCC(=O)Nc2cc(F)ccc2F)c2c(C)c(C)oc2n1 +O=C(Nc1cccc2cnccc12)c1cc(-c2cccs2)n[nH]1 +O=C(Cc1ccc(-n2cccc2)cc1)NC1CCSc2ccccc21 +CCC(C)C(NC(=O)CNC(=O)c1ccccc1)C(N)=O +COC(=O)c1ccc(C(=O)Nc2ccc3nc(C4CCC4)[nH]c3c2)cc1 +C#Cc1cccc(NC(=O)NCc2ccc(C)cc2N(C)C)c1 +Cc1cc(OCc2ccccc2)ccc1NC(=O)c1ccn(C)c(=O)c1 +CCc1cc(C(=O)Nc2ccc(S(C)(=O)=O)cc2)sc1C +O=C(NC1CCC1)c1ncoc1-c1ccc(F)cc1 +Cc1cc(OC(F)F)c(C(=O)N2CCN(C(=O)CO)CC2)s1 +O=C(Nc1cccc(CN2CCOCC2)c1)c1ccc2c(c1)OCO2 +CCCn1cc(NC(=O)c2[nH]nc(C)c2Br)ccc1=O +CNC(=O)c1ccc(NCC(=O)Nc2ccc(C)c(C)c2)cc1 +Nn1c(SCc2n[nH]c(=O)[nH]2)nnc1-c1ccccc1Cl +CCn1cc(C(=O)Nc2cccc(Cl)c2)c(=O)c2cc(F)ccc21 +Cc1ccc(C)c(C(C)C(C#N)N2CCOCC2)c1 +CCN(CC)C(=O)c1ccc(NCC(=O)N(C)C)cc1 +CC(=O)Nc1ccc(C)c(NC(=O)N(C)Cc2ccncc2)c1 +CCC(CC)NC(=O)Cn1nc(C)c2ccccc2c1=O +COc1ccccc1OC(C)C(=O)N1CCN(C2CCCCC2)CC1 +CCC(=O)Nc1cc(F)c2nc(N3CCOCC3)ccc2c1 +Cc1ccc(O)c(NC(=O)c2cc(S(C)(=O)=O)ccc2Cl)c1 +Cc1cnc(NC(=O)c2ccc(NC(=O)c3cccs3)cc2)s1 +O=C(COc1ccc(Cl)cc1Br)C1=NC=CC1 +CCCOC(=O)c1ccc2cnc(C3CC3)n2c1C +CC1CN(Cc2ccccc2)CCN1C(=O)c1cccc2cn[nH]c12 +CCCc1cc(=O)n(CC(=O)Nc2ccc(C(C)C)cc2)cn1 +Nc1cccc(CC(=O)Nc2ccc(Cl)cc2F)c1 +CCc1ccccc1NC(=O)NC(C)CCCO +CC(C)c1noc(C(C)N2CCN(c3ccc(C#N)cc3F)CC2)n1 +COc1ccc(CNC(=O)C2CCN(c3ccc(C)cc3)C2=O)cn1 +CCCn1cc(NC(=O)C2COc3ccc(Cl)cc3C2)ccc1=O +Cn1nnnc1Sc1ccc(N)c(OC(C)(C)C)n1 +COc1ccc(Br)cc1-c1nccc(C)n1 +CCCn1cc(C(=O)N2CCCC(C#N)C2)c(C)n1 +c1cc2c(cc1-c1nc(C3CCCC3)no1)CCN2 +O=C1COc2ccc(C(=O)Nc3cccc(-n4cnnc4)c3)cc2N1 +Nc1ccc(S(=O)(=O)c2ncc(C(F)(F)F)cc2Cl)cc1 +CCc1noc(CN(C)c2ccc(F)c(F)c2)n1 +CCCC(C)NC(=O)c1ccc(S(=O)(=O)N(C)C)o1 +Cc1cccc(OCCNC(=O)Cn2ncc3ccccc3c2=O)c1 +COC(=O)c1cc(C)sc1NC(=O)N1CCOCC1 +Oc1ccc2c3c(ccc2c1)CCNC3c1cc[nH]c1 +CC(C)(C)C(=O)COC(=O)c1ccc(C(N)=O)cc1 +COC(=O)c1cc(C(C)C)ccc1NCc1nc(C2CC2)no1 +Cn1cnc(CNC(=O)C2CCOc3ccccc32)n1 +N#Cc1cccc(S(=O)(=O)N2CC(O)(C3CC3)C2)c1 +CCN(C(=O)CSc1nccc(=O)[nH]1)C1CCCCC1 +CC1CCCCN1C(=O)C1CCN(C(=O)OC(C)(C)C)CC1 +CC(=O)c1cc(N)c2c(c1)N(C)C(=O)C(C)(C)CO2 +NC(=O)c1ccc(C(=O)Nc2ccc3ccccc3n2)s1 +CN1C(=O)C2(N=C(N)N=C3Sc4ccccc4N32)c2ccccc21 +Cc1ccc(N(CCC#N)CCC#N)cc1Br +c1ccc(-n2ncc3c(SCCc4ccncc4)ncnc32)cc1 +CC(Sc1nnc(C2CC2)n1C)C(=O)Nc1ccc(Cl)cn1 +CN1C(=O)c2cccc3c(S(=O)(=O)N4CCCCCC4)ccc1c23 +O=C(CNC(=O)Cc1cccc(F)c1)NCCCO +COc1ccc(Cl)cc1C(O)Cn1cc(N)cn1 +CCc1nncn1CCNc1ccc2cccc(Br)c2n1 +CCCC(C(=O)N1CCNCC1)c1cccs1 +Cn1cc(COc2ccc(Cl)cc2CO)cn1 +COc1cn(-c2ccccc2)nc1C(=O)OCc1nc(C)c(C)o1 +Cc1ccccc1CC(=O)NCC(O)c1ccco1 +Cc1c(-c2ccc(Br)cc2)nc(N)[nH]c1=O +CC(C)CN1CC(C(=O)NCCc2[nH]nc3c2CCCC3)CC1=O +CN1CCN(C(=O)C2CCOC3CCN(c4ncccn4)CC32)CC1 +Cn1c(=O)c(SCC(=O)NCc2cccs2)nc2ccccc21 +CC(=O)c1cccc(OCC(=O)N2CCCc3ccccc32)c1 +CC(C)CCn1cccc1CN1CCN(C(C)C(N)=O)CC1 +CCCC(=O)Nc1cccc(NCC(=O)NCC)c1 +CCCCN(CC)C(=O)NCC(=O)NC(C)(C)C +COC(=O)C1CCCN1C(=O)c1ccc(OC(C)C)cc1 +Cc1ccc(CC(=O)NCCCN2CCCC2=O)cc1 +O=C(Cc1cc(-c2ccccc2)on1)Nc1cnn(CC(F)F)c1 +O=C(COc1ccc2ccccc2c1)Nc1ncccn1 +O=C(COc1nnc2ccccn12)NCc1ccc(F)cc1 +Nc1ccccc1N1CCC(OCc2ccccc2F)CC1 +CC(NC(=O)Nc1cn(C)nc1-c1ccccc1)c1ccccc1 +O=C(C1CCCC1)N1CCN(Cc2cccnc2)CC1 +CCC(C)C(NC(=O)N1CCCCC1)C(=O)OC +Cc1cnn(-c2ccc(C(=O)Nc3ccnc(C)c3)cc2)c1 +NC(=O)C1CCN(C(=O)C2(c3ccccc3F)CCCC2)CC1 +CCOc1ccc(-c2nc(C3CCOC3)no2)o1 +O=C(CN1CCOC1=O)N(Cc1cocn1)Cc1cocn1 +COCCNC(=O)c1cc(OC)c(OC)cc1N +O=C(CC1CCN(C(=O)C2CCCCC2)CC1)N1CCCC1 +O=C1Nc2ccccc2OC1CC(=O)N1CCCCCC1 +CN(C(=O)c1cccc(-c2ccoc2)c1)C1CCCc2c1cnn2C +O=C(NC1CCN(c2ccccc2Br)C1)c1ccoc1 +Cc1nc(NC(=O)CCCn2sc3ccccc3c2=O)sc1C +CC(Sc1nnc(-c2ccc(Cl)cc2)n1C)C(=O)N(C)C +COC(=O)c1ncoc1-c1ccccc1C(=O)NC1CCCC1 +CN1Cc2ccccc2CC1C(=O)NCCN1CCOC1=O +CCC(NCc1ccco1)C(O)c1ccc(C)cc1C +Cc1ccc(CN(CCC#N)Cc2ccccn2)cc1C +C=CCn1c(SCc2c(C)noc2C)nc2ccccc2c1=O +CC(NS(=O)(=O)CCn1cnc2ccccc21)c1ccccc1 +O=C(OCC(=O)N1CCCCCC1)c1cc(-c2ccccc2)on1 +Cc1cc(C)n(-c2cccc(-c3cnc(N)cn3)c2)n1 +Cc1ccc2[nH]c(=O)cc(C(=O)NCCc3c[nH]cn3)c2c1 +OCc1nnn(-c2nc(-c3ccccc3)cs2)c1C1CCC1 +CCOc1cc(C(=O)NC2(C)Cc3ccccc3C2)ccn1 +CCOc1cc(C(=O)Nc2nccn(C)c2=O)ccn1 +CC(=O)Nc1ccc(C)c(NCc2ccc(C#N)cc2)c1 +COc1cc(SC)ccc1C(=O)Nc1nc(C)c(C(C)=O)s1 +COc1ccc2[nH]nc(C(=O)N3CCC(n4nc(C)cc4C)C3)c2c1 +Cc1n[nH]cc1NC(=O)CNC(=O)C1CCCC1 +CC(=O)NC1CCN(c2nccc(-c3cnn(C)c3)n2)C1 +CC1C(c2cnn(Cc3ccccc3)c2)CCc2nc(N)nn21 +CC(C)N(C)S(=O)(=O)NCC1(c2ccc(F)cc2)CCOCC1 +CN(CCO)C(=O)CCc1nc2ccccc2s1 +NC(=O)C(NCc1cnn(-c2ccc(F)cc2)c1)c1ccccc1 +CN(C)C(=O)c1ccc(C(=O)Nc2ccnn2C2CCCCC2)cc1 +Cc1cccc(C(C)C)c1NC(=O)c1cccc(N)c1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccccc2C)cc1 +Cc1cc(NC(=O)CSc2nc3c(cc2C#N)CCCCC3)no1 +CCCn1nccc1NC(=O)c1ccc(OC)cc1 +CCC(C(=O)Nc1ccc(C#N)cc1)n1cc(Cl)ccc1=O +O=C(CCCNC1=NS(=O)(=O)c2ccccc21)NC1CCCC1 +CC(C)C1(CNC(=O)N2CCC(OCc3ccccc3F)CC2)CC1 +COc1ccccc1C(C)N(C)S(=O)(=O)N1CCCC(C)C1 +CC(C)NC(=O)C(O)(c1ccccc1)c1ccccc1 +O=C(CCCc1cccs1)OCC(=O)N1CCCC1 +CC(C)CSc1ccc2c(c1)NC(=O)C(C)(C)O2 +Cc1cccc(CN2CCN(C(=O)c3cc(F)cc(F)c3)CC2)c1 +CCC(=O)NC1CCOc2c(Cl)cc(C(O)CC)cc21 +COCc1ccc(C(=O)Nc2ccccc2N2CCCC2)cc1 +COc1ccc(C(=O)NCc2cn3ccccc3n2)cc1 +CC(C)CCNC(=O)c1ccc(-c2cc(N3CCCC3)ncn2)cc1 +OCc1cc(CC2(NCc3ccccc3Cl)COC2)no1 +COc1ccc(C(=O)Nc2ccc(S(C)(=O)=O)cc2)cc1OC +CCSc1nc(CC(=O)N2CCCC3(CCOC3)C2)cs1 +COc1ccccc1C(=O)NCC1(O)CCc2ccccc2C1 +O=C(NC1CCCC1)C1c2ccccc2C(=O)N1CCc1ccccc1 +Cc1ccn(CCNC(=O)C(C)Cc2cccs2)n1 +O=C(Cn1cccc(C(F)(F)F)c1=O)Nc1cccc2ncccc12 +CC(C)C(CCO)NC(=O)Nc1ccc2c(c1)CCCO2 +COc1ccc(C(=O)C(C)Sc2nncs2)cc1 +COC(=O)c1cc(COc2cc(C)ccc2C(N)=O)c(C)s1 +COc1ccc(CNc2c(C)nn(C)c2C)cc1C +C=CCNC(=O)c1cnc(COc2ccccc2F)nc1N +CCOc1ccc(N(C)S(=O)(=O)Cc2cccc(C#N)c2)cc1 +Cc1nccn1-c1ncccc1NC(=O)CCNC(=O)c1ccco1 +COc1ccccc1CNC(=O)Cc1c(C)nc(C)[nH]c1=O +Cc1cccc(C(=O)Nc2sc3c(c2C(=O)NC2CC2)CCC3)c1 +O=C(C1CC2CN(Cc3ccccc3F)CC1O2)N1CCOCC1 +CC(C)c1csc(C(=O)N2CCCc3c(C(N)=O)cccc32)n1 +Cc1cc(C)c(CNC(=O)CCc2ccco2)c(=O)[nH]1 +O=C(NCc1cc(Cl)c2c(c1)OCCO2)c1cccc(F)c1 +Cn1ncc2c(SCC(=O)NCCC3CCCCC3)ncnc21 +Cc1cnc(C(=O)N2CCN(c3oc(C4CC4)nc3C#N)CC2)cn1 +CCc1cccc(C)c1NC(=O)C(C)n1sc2ccccc2c1=O +COc1ccc(C(=O)N2CCN(c3ccccc3F)CC2)c(OC)c1 +COCCN1CC(C(=O)NCc2ccco2)CC1=O +CC=CCOC(=O)Cc1csc(NC(=O)c2cccs2)n1 +COc1cccc2[nH]c3c(N4CCC(C)CC4)ncnc3c12 +O=C(NCc1cccc(Br)c1)C1CCC1 +CCNC(=O)C1CCCN(C(=O)NCc2c(CC)noc2CC)C1 +Cc1noc(C)c1C(=O)NCCc1c(Cl)cccc1Cl +Cc1ccc(S(=O)(=O)N2CCN(C(=O)C(C)C)CC2)s1 +CN(Cc1ccc(F)cc1)C(=O)c1ccc(N2CCCC2=O)cc1 +Cn1cccc1C(=O)N1CCCCC1c1nncn1Cc1ccccc1 +CCOC(=O)c1ccc(NCc2ccccc2)cn1 +COC1COCCN(Cc2c[nH]c3ccccc23)C1 +CC(CNC(=O)NCC12CC3CC(CC(C3)C1)C2)N1CCOCC1 +CCC(CC)C(=O)N1CCC(c2ccncc2)CC1 +Cc1cc(C)cc(NC(=O)Cc2ccc(O)cc2)c1 +COc1c(CN2CCN(Cc3c(C)noc3C)CC2)c(C)nn1C +O=C(Cn1cnc2ccccc21)NCc1ccc(N2CCCC2=O)cc1 +COCCCNC(=O)Cc1nc(-c2ccccc2)oc1C +O=c1[nH]cnc2c1CCN(c1nccc(-c3cccnc3)n1)CC2 +Cc1cc(NC(=O)C2CC(=O)N(c3ccccc3C)C2)no1 +CS(=O)(=O)N1CCN(C(=O)CCCOc2ccc(F)cc2)CC1 +COc1cc(NC(=O)c2cnn(-c3ccccc3)n2)cc(OC)c1 +COC(=O)C1(NC(=O)CCC(=O)c2cccs2)CCCC1 +COc1ccccc1-c1nnc(SC(C)C(=O)N(C)CCC#N)o1 +CCOC(=O)Nc1nnc(Cc2ccccc2)s1 +O=C(NCCCNC(=O)c1cccnc1)c1ccncc1 +COc1cccc(OC)c1C(=O)Nc1nc(C)c(C(C)=O)s1 +Cc1ccc(S(=O)Cc2cn3cc(Cl)cc(Cl)c3n2)nc1 +CCOC(=O)c1nn(Cc2ccccc2F)c2ncccc12 +CC(NC(=O)c1cccc(-c2ccoc2)c1)c1cnn(C)c1 +CCOC(=O)C1CCN(Cc2nc3c(F)cccc3[nH]2)CC1 +CCc1nc(N2CCCC2=O)sc1C(=O)NCc1ccc(F)cc1 +O=C(NCc1cccnc1)c1c2ccccc2n2ccsc12 +CNC(=O)C1CN(C(=O)c2ccc(F)cc2C)CCO1 +CC(CNC(=O)NCCc1nnc2n1CCC2)N(C)c1ccccc1 +CC1CN(C(=O)c2c[nH]nc2-c2cccc(F)c2)CCC1(C)O +Cc1ccc(C(C)NC(=O)C2CCCCN2S(C)(=O)=O)cc1F +Cc1cc(OCC(=O)NCCc2nc(N)no2)ccc1C(C)C +Cc1cc(C)cc(CCNC(=O)CCNC(=O)c2cccs2)c1 +COc1ccc(COC(=O)C(N)c2ccccc2)cc1F +Cc1ccc(C(=O)NC(C(=O)Nc2cccnc2)C(C)C)cc1 +Cn1nnnc1SCC(=O)Nc1ccc(Cl)c(Cl)c1 +O=C(NCCNC(=O)c1ccc(F)cc1)NCc1ccc(F)cc1 +COc1ccc(NC(=O)Cn2ccc3c(=O)[nH]ccc32)c(OC)c1 +CCOc1ccccc1C1CC(NC(C)=O)CC(C(C)(C)C)O1 +O=S(=O)(Cc1ccon1)c1ncccc1Cl +CNC(=O)NCC(=O)NC1CC(C)(OC)C1(C)C +COCCNC(=O)c1ccc2c(c1)nnn2Cc1ccc(OC)cc1 +N#Cc1ccc(N2CC3(CCN(c4ncccn4)C3)CC2=O)cc1 +Cc1ccc(F)c(NC(=O)c2ccc(CO)cc2)c1 +CCC(C)N(C)C(=O)COc1ccc(Cl)cc1 +Cc1noc(C)c1NC(=O)CCn1c(=O)oc2ccccc21 +Cc1ncnc2c1CCN(C(=O)c1cccnc1)CC2 +O=C1CCN(C(=O)c2ccccc2)c2ccccc2N1 +Cc1nc(C)c(C(=O)N2CCC(C(=O)N3CCCCCC3)C2)o1 +Cc1cc(C(=O)NCCN2CCN(c3ccc(F)cc3)CC2)[nH]n1 +COc1ccc2[nH]cc(C(=O)N3CCCCC3)c(=O)c2c1 +CC(=O)NC(C(=O)NC1CCC(C)CC1)C(C)C +CC1(NC(=O)Nc2ccn(-c3ncccc3Cl)n2)CCC1 +O=S1(=O)CC(S(=O)(=O)c2ccccc2)c2ccccc21 +COc1cccc(C(=O)Nc2cccc(N(C)C(C)=O)c2)c1F +Cc1cnc(NC2CCN(S(=O)(=O)Cc3ccccc3)CC2)nc1 +COc1cc(OC)cc(N2CCC(N(C)CC(F)F)C2=O)c1 +Cc1ccc(CC(=O)Nc2nnc(-c3cc(C)n(C)n3)o2)c(C)c1 +Cc1n[nH]c(SCC(=O)NCc2cccc(C#N)c2)n1 +CC(NC(=O)OC(C)(C)C)c1nnc2n1CCC2 +CCC1CNc2ccc(C)cc2N1Cc1cccnc1 +CC(=O)c1cccc(NC(=O)NCc2cscn2)c1 +COc1ccccc1OCCN(C)Cc1cnc2ccc(C)cn12 +NC(=O)C1CCN(C(=O)c2csc(-c3ccsc3)n2)CC1 +O=C(c1ccncc1)N1CCC2(CC1)CC(Oc1cccnc1)C2 +CCNC(=O)CN1CCN(C(=O)COC2CCCCC2C)CC1 +Cc1ccc(CNS(=O)(=O)Cc2cccc(C#N)c2)c(C)c1 +CCc1ccc(NC(=O)C(C)S(=O)(=O)c2ccc(OC)cc2)cc1 +Cc1cc(C)n(C2CCN(C(=O)c3cnco3)CC2)n1 +COc1cccc(-c2cc(C(=O)NCCN3CCOCC3)no2)c1 +O=C(C1CCOCC1)N1CCC(c2nc3ccccc3s2)CC1 +CC(=O)Nc1ccc(C(=O)Nc2ccccc2C(=O)NC2CC2)cc1 +CC1CCCC(CNC(=O)CNS(C)(=O)=O)C1 +COc1ccc(-c2nc(N)n(S(C)(=O)=O)n2)cc1 +CC(C)(C)NC(=O)NC1CCN(c2nccs2)CC1 +O=C(CSc1ccc2nncn2n1)Nc1ccc2c(c1)OCCO2 +Cc1ccc(-c2cnc(Oc3ccc(S(C)(=O)=O)cc3)nc2)cc1 +COc1ccccc1OCc1ccc(C(=O)Nc2nc(C)no2)o1 +CC1CCCC(OC(=O)CN(C)S(=O)(=O)c2cccnc2)C1 +COc1cccc2c1cc1c(=O)n(CC(=O)N3CCCC3)nc(C)n12 +C#CCNC(=O)Cc1csc(-c2ccc3c(c2)OCO3)n1 +Cc1ccc(N2CC(C(=O)OC(C)c3ccccn3)CC2=O)cc1 +Cc1oc(C)c(C(=O)NC2CCN(c3c(F)cccc3F)C2)c1C +NC(=O)C1CCN(C(=O)c2nccc3c(F)ccc(N)c23)CC1 +Cc1nn(CC(=O)NC2CCCCC2)c(C)c1N +Cc1nn(-c2ccccc2)cc1CNCCc1nnc2ccccn12 +O=C(OCCCc1cccnc1)C1CC2CCC1C2 +CCCCCOc1ccc2c(c1OC)C(CO)NCC2 +CCC(=O)Nc1ccc(Cl)c(NC(=O)NCCCOC)c1 +OCCn1c(-c2cccc(-n3cccn3)c2)nc2ccccc21 +CC(C)C(=O)c1ccc(CC2CCC(CN3CCOCC3)O2)s1 +Cc1cc2c(SCc3nccn3C(C)C)ncnc2s1 +COCc1cccc(C(=O)N(C)c2ccc(F)c(F)c2)c1 +CCC(OC)C(=O)Nc1ncc(C(=O)OC)s1 +CCC(=O)N1CCc2cc(C(=O)N(CC)CCO)ccc21 +CC1CCCCC1NC(=O)c1ccc(S(C)=O)cc1 +Cc1nc(SCC(=O)N(Cc2ccccc2)C(C)C2CC2)oc1C +COCc1nc(CN2CCOC(c3nc(C(C)C)n[nH]3)C2)cs1 +O=C(CSc1nncs1)Nc1cccc(-c2nccs2)c1 +CCC(=O)c1cnn(Cc2cc(C)ccc2OC)c1 +CC(CC(=O)N1CCCS1(=O)=O)c1ccccc1 +N#Cc1c2c(c(-c3ccncc3)[nH]c1=O)CCCC2 +Cn1cnnc1SCc1nc(CC(=O)NCc2ccccc2)no1 +COc1cc(-c2nnc(N3CCOCC3)o2)cc(OC)c1OC +CC(C)NC(=O)c1ccccc1NC(=O)C1CCCC1 +CN(CCCC(O)c1cccnc1)C(=O)OC(C)(C)C +O=C(NC1CNCc2cc(Cl)ccc21)c1ccccc1Cl +COCCN1CCCC2(CCN(C(=O)Cc3ccsc3)C2)C1=O +COC(=O)CC(CC(C)C)c1ccc(OC)c(C)c1 +Cn1cnc(S(=O)(=O)NCCc2ccsc2)c1 +Cc1cc(CS(=O)(=O)NC2(CO)CCCC2)no1 +Clc1ccc2c(c1Cl)C(c1cnccn1)NCC2 +CCC(C)C(NC(=O)C(C)NC(=O)C(C)(C)C)C(N)=O +Nc1cccc(NC(=O)CCn2c(=O)oc3ccccc32)c1 +Cc1ccc(S(=O)(=O)C(c2ccccc2)c2c(C)noc2C)cc1 +CC(=O)c1cccc(NC(=O)c2cnn(-c3cccc(C)c3)c2C)c1 +COc1ccc(Cl)cc1NC(=O)C(C)Sc1ccc(N)cc1 +CC(=O)c1ccc(C(=O)Nc2ccc(-c3ccccn3)cn2)cc1 +CN(C(=O)C1CCN(S(C)(=O)=O)CC1)C1CCCCC1O +CC(C)NC(=O)C1CCN(c2ccc(C#N)c(Cl)c2)CC1 +CC(C)N(C)C(=O)NCc1ccccc1-n1ccnc1 +CCC(=O)NC(c1ccccn1)C1CCC(CNC(C)=O)CC1 +COc1ccc(NC(=O)c2ccc(Br)cc2O)cn1 +COc1cc(-n2ncc3c(=O)[nH]cnc32)cc(OC)c1OC +COCCC(=O)N1CCNC(=O)C1c1ccccc1C(F)(F)F +CC(NS(=O)(=O)c1cc(N)ccc1F)c1cccs1 +Cc1nc(C)c(C#N)c(SC(C)C(=O)NC2CC2)n1 +CC(C)Oc1cccc(C(C)NC(=O)NCC2CCCO2)c1 +CC(C(=O)NC1CC2CCC1C2)N(c1ccccc1)S(C)(=O)=O +CC1CCN(C(=O)c2cccc3c2-c2ccccc2C3=O)CC1 +O=C(CCOc1cc(Cl)cc(Cl)c1)NCc1ncc[nH]1 +Cc1ccc(C(C(=O)NC2Cc3ccccc3C2)N(C)C)cc1 +COc1cccc(-c2nc(-c3cccnc3)n[nH]2)c1 +OCCNc1cc(-c2cnccn2)c2cc[nH]c2n1 +Cc1c(Br)cnc(N)c1Br +O=C(CNc1ccc(F)c(F)c1)N1CCCCC1 +Cc1nc(-c2cccc(NC(=O)NCc3ncoc3C)c2)oc1C +CS(=O)(=O)Nc1cnn(COc2cccc(Cl)c2)c1 +CCc1nnc(NC(=O)N(CC(C)C)CC(C)C)s1 +COCc1nn(CC2CC2)c2c1CN(C(=O)c1ccsc1)CC2 +CC(C)(C)NC(=O)CSc1ncc(-c2ccc(F)cc2)o1 +CC(=O)c1ccccc1NC(=O)c1ccc(C)c(F)c1 +Cc1cc(C)c(S(=O)(=O)N(C)CCc2ccccn2)c(C)c1 +COCC(C)Nc1cc(OC)c(Cl)cc1OC +Cc1ccc(-c2csc(NC(=O)c3ccn(C)n3)n2)c(C)c1 +CCC(C)C(NC(=O)c1ccc(S(=O)(=O)C(F)F)cc1)C(N)=O +COc1nc(C)cc(C)c1CNC(=O)C1CCOc2ccccc2C1 +CC(C)CNC(=O)c1ccc(NC(=O)N2CCOCC2)cc1 +COc1ccc2[nH]cc(S(=O)(=O)c3cccc(C#N)c3)c(=O)c2c1 +CCOC(=O)C1CCCN(C(=O)c2ccc(Cl)c(Cl)c2)C1 +O=C(CSc1ccc(F)c(F)c1)N1CCCCCC1 +O=C(Nc1ccccc1Cl)c1ccc(-n2ccnc2)cc1 +COC(=O)NCC(=O)N(C)Cc1ccc(-n2cccn2)cc1 +CCNc1c(C)cc(Cc2cnc(N)nc2N)c2cccnc12 +CCCNC(=O)C(C)NC(=O)C(C)Oc1ccc(Cl)cc1 +O=C(Cc1ccc(F)cc1)NC1CCCN(Cc2ccccc2)C1=O +Cc1sc2nc(Cc3ccccc3)n(CC#N)c(=O)c2c1C +CN(C(=O)Nc1cccnc1)C1CCCc2ccccc21 +CCc1ccsc1C(=O)NCc1cccc(OCC(=O)N(C)C)c1 +N#Cc1ccc(C(=O)N2CC=C(c3c[nH]c4ccccc34)CC2)cc1 +O=c1oc(-c2ccc(F)cc2)nn1Cc1nnc(-c2ccccc2)o1 +CCCCn1cnc2sc(C(=O)OC(C)C)c(C)c2c1=O +C#CCC(NC(=O)c1ccc(OC)cc1)c1ccccc1 +Cn1cc(C(=O)N2CCC(Cn3ccnn3)CC2)c(C(C)(C)C)n1 +Fc1cccc(Cn2cc(-c3noc(-c4ccncc4)n3)nn2)c1 +CCn1nc(C(=O)N2CCC3(CCCCC3)CC2)ccc1=O +Cc1ccc(CN(C(=O)NCCNC(=O)c2cccnc2)C(C)C)o1 +O=C(NC(Cc1ccccc1)C1CC1)c1ccccn1 +Cc1cc2ncc(C(C)NCc3ccc(F)c(CO)c3)c(C)n2n1 +CC1(C)C(=O)Nc2c(F)cc(C(O)Cc3cccs3)cc21 +O=C(NCC(C1CCOC1)N1CCOCC1)Nc1nccs1 +COCCNc1nc(NCc2ccc(C)cc2)c2cnn(C)c2n1 +CCNC(=O)c1cccc(NC(=O)c2cc(C)cc(C)c2)c1 +NC(=O)Cn1ccc(NC(=O)c2occc2COc2ccccc2)n1 +CSc1ccsc1C(=O)Nc1ccc(NC(=O)NC(C)C)cc1 +CN(CC(=O)N(C)C1CC1)c1ncnc2nc[nH]c12 +O=C(CC1CCCO1)N1CCOc2ccc(F)cc21 +CC1CN(S(=O)(=O)c2cccc(Cl)c2Cl)CCO1 +Cc1cc(CN2CCN(C(=O)NCCC3=CCCCC3)CC2)no1 +O=C(NC1CC(O)C(CO)C1)c1ccc(Cl)cc1Cl +N#Cc1cccc(CNc2c(N)cccc2Cl)c1 +CN(C(=O)c1cccc2[nH]ccc12)c1ccc(F)cc1 +CC(C)NC(=O)Nc1ccccc1C(=O)OCC(=O)N1CCCCC1 +CCn1ccc(C(=O)Nc2nc3cc4c(cc3s2)OCCO4)n1 +CC(CO)NC(=O)CCCOc1cccc(Br)c1 +Nc1cccc(-c2nnnn2-c2cccc(Cl)c2)c1 +CN(CCCNC(=O)c1cnn[nH]1)c1ccccc1F +Cc1c(C(=O)OC(C)C)sc2nc3n(c(=O)c12)CCCCC3 +O=C(CNC(=O)c1ccc(Cl)c(Cl)c1)NCC(F)(F)F +COC(=O)Nc1cc(NC(=O)c2c(F)cccc2F)ccc1F +CC(C)NC(=O)C(NC(=O)c1cc2c(s1)SCC2)C(C)C +CC1CCCC(NC(=O)NCc2cccc(Cn3ccnc3)c2)C1 +CCNC(=O)c1ccc(NC(=O)c2cccc(Br)c2)cc1 +Cc1noc(C2CCCN2C(=O)c2cscn2)n1 +O=C(CNC(=O)Cc1ccccc1)NCc1cccc(Cl)c1 +CSc1ccsc1C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +Cc1c(-c2nn3cc(N)nc3s2)c2ccccc2n1C +CCCNC(=O)CCNC(=O)Nc1ccc(Cl)c(C(=O)NC)c1 +CC(=O)NC(C)(C)c1noc(CCCNC(=O)c2cccs2)n1 +O=C(Cc1cc2c(s1)CCCC2=O)NCc1ccccc1F +CC1(CNC(=O)N2CCc3ccc(Cl)cc3C2)COC1 +CCc1noc(CN(C)C(=O)NCc2cn(-c3ccccc3)nn2)n1 +Cc1ccc(NC(=O)CCc2cnn(C)c2)c(C)c1 +OCc1ccccc1OCc1ccccc1OC(F)F +CCC(C)n1c(C)nc2c(N)cc(C(F)(F)F)cc21 +CC(C)CC(C(=O)C(C#N)c1ccccn1)N1CCCCC1=O +COc1ccc(NC(=O)NC(C)C(=O)N2CCCCC2)cc1C +Fc1ccc2oc(CN3CCOCC3C3CC3)cc2c1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2cccnc2)CC1 +Cc1cc(C)cc(C(=O)N(Cc2cccs2)CC2CCCO2)c1 +Cc1occc1COC(=O)C1CCN(c2nc3ccccc3o2)CC1 +CCOC(=O)c1sc(NC(=O)c2ccc(F)cc2Cl)nc1C +CC(C)c1cc(Br)ccc1NC(=O)C1CCC(=O)NC1 +O=C(CNC(=O)c1cccc(F)c1)NCc1ccsc1 +CCn1nc(C)c2ncnc(NCc3csc(C)n3)c21 +COc1ccc(N2CC(C(=O)Nc3nncs3)CC2=O)c(OC)c1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)OCCCO3)c(F)c1 +CC(CNC(=O)N(C)C(C)C)Oc1ccccc1 +COCCc1ccc(OS(=O)(=O)c2ccc(OC)c(C)c2)cc1 +Cc1ccc2ncc(CN(Cc3ccc(O)cc3)Cc3ccco3)n2c1 +CC(C)N(C)S(=O)(=O)N(C)Cc1csc2ccccc12 +Cc1ccc2ncc(C(=O)NC3CCN(C4CCCCC4)C3=O)n2c1 +CN(Cc1cccc(F)c1)C(=O)c1cnc2ccccc2n1 +O=C(Nc1cc(C2CCCCCC2)[nH]n1)C1CCOC1 +Cc1n[nH]cc1CNS(=O)(=O)c1cn[nH]c1C +Cc1ccc(NC(=O)C(C)NC(=O)C2CCCCC2)cc1 +CN(C)C(=O)c1cc(NC(=O)c2cccn(C)c2=O)c(=O)n(C)c1 +CCN(C1=C(C(N)=O)S(=O)(=O)c2ccccc21)c1ccccc1 +Cc1cccc(C(N)=O)c1NCC(=O)NCCc1c(F)cccc1F +COc1ccc2c(c1)C(c1ccc(C(C)=O)s1)NCC2 +COCCCn1c(C(C)C)ccc(C(C)=O)c1=O +COc1ccc(CNc2cccnc2-n2cccn2)c(OC)c1OC +Cc1csc(C(C)N(C)C(=O)c2ccc(-n3cnnc3)nc2)n1 +Cc1ccc(C(=O)OCC(=O)NC(C)(C)C)c(O)c1 +O=C(OCCNc1cccnn1)c1ccc(-n2cccc2)c(F)c1 +O=C(NC1CCOc2ccccc21)c1ccc2ccccc2c1 +CCCCS(=O)(=O)N1CCCC(C(=O)Nc2ccon2)C1 +COc1ccc(C(C#N)N2CCN(C(=O)C3CC3)CC2)cc1 +Cc1nc2ncccn2c1C(=O)N1C2CCC1CC(=O)NC2 +O=C(Nc1ccccc1)C1CCCN1C(=O)c1cc2n(n1)CCCO2 +O=C(NCCc1ccccc1)c1nc(-c2ccccc2)no1 +COc1c(CNc2cnn(-c3ccccc3)c2)c(C)nn1C +CN(C)C(=O)c1cccc(NC(=O)CC2CCCCC2)c1 +CCC(=O)Nc1cccc(NC(=O)c2c(OC)cccc2OC)c1 +Cc1cccc(C2NC(=O)N(C)C3=C2C(=O)NC3)c1C +Cc1ccc(C(=O)Nc2ccc(F)c(Cl)c2)c(N)n1 +COc1c(Cl)cc(C(=O)N(C)CC(=O)N(C)C)cc1Cl +CCC(C)NS(=O)(=O)c1ccc(NC(=O)C(C)(C)C)cc1 +Cc1ccc(S(=O)(=O)N2CCN(C)CC2)cc1C +O=S(=O)(NCc1ccsc1)c1cccs1 +CCOCC1CCCN(C(=O)c2c(C)c(C)nn(C)c2=O)C1 +CCOC(=O)Nc1cc(C2=NC(C(=O)OC)CO2)ccn1 +CCc1cc(-c2ccc(Br)cc2)nc(N)n1 +COc1ccc(CNC(C)(C#N)C(C)C)c(F)c1 +CCn1c(C)cc(N2CCC(C)CC2)c(C#N)c1=O +CCCc1cc(=O)[nH]c(SCc2cc(=O)n3c(C)cccc3n2)n1 +Cc1ccc(CN2CCCC(c3nncn3C)C2)c(C)c1 +Cc1ccc(F)cc1NC(=O)c1cn(C)nc1C(F)(F)F +CC(=O)c1cc(CNC(=O)OC(C)(C)C)cc(C(F)(F)F)c1 +Cn1c(=O)c(Cn2cnc3ccccc3c2=O)nc2cc(F)ccc21 +Cc1ccnc(NC(=O)NCCCSc2nc3ccccc3o2)n1 +CC(=O)c1cccc(NC(=O)c2ccccc2O)c1 +O=C(Nc1ccc(OC(=O)N2CCCCC2)cc1)N1CCOCC1 +O=C(NCc1ccc(CN2CCCC2=O)cc1)Nc1ccccn1 +COc1ccc(C(C)C)cc1C(=O)Cn1cccn1 +Cc1c(CNC(=O)Nc2cc(F)ccc2Br)cnn1C +COc1ccc(-c2nnc3c(n2)c(=O)n(C)c(=O)n3C)cc1 +O=C(Cc1ccccc1)NCC(=O)NC1CC2CC1C1CCCC21 +COc1cccc(NC(=O)c2cnn(Cc3ccccc3Cl)c2)c1 +CS(=O)(=O)NCCC(=O)NC12CC3CC(CC(C3)C1)C2 +Cc1cc(C)n(-c2ccc(C(=O)N(C)CC(O)CO)cc2)n1 +Cc1ccccc1-n1c(-c2ccccc2)cnc1SCC(N)=O +Cc1[nH]c(NCC2CCCO2)nc(=O)c1CCC(C)C +Cc1cc(C)nc(Nc2nc(C(=O)Nc3ccccc3)cs2)n1 +CCOC(=O)C1CCN(C(=O)c2ccccc2)CC1 +CCCc1nc(-c2cc3ccccc3nc2OC)no1 +CC(C)c1ccc(C(=O)NCc2cccnc2)c(N)n1 +OCCCOC1CCN(Cc2nc(-c3ccccc3)cs2)CC1 +Cn1cc(Br)cc1C(=O)Nc1ccc(-n2ccnc2)cc1 +COc1cccc(OC)c1C(=O)NC(C#N)C(C)C +Cc1cc(C)c(CNc2ccc3[nH]nc(C(N)=O)c3c2)c(C)c1 +Cc1oc(=O)oc1Cn1c(=O)c2ccccc2n(C)c1=O +Cc1cc(C)n(-c2ccc(NC(=O)C(C)NC(N)=O)cn2)n1 +CC1CN(S(=O)(=O)N2CCN(Cc3ccon3)CC2)CC(C)O1 +Cn1cc(CNC(=O)CCc2ccccc2Cl)cn1 +Cc1ccc(-c2cc(C(=O)NC3CC3)c3ccccc3n2)o1 +Cn1ncc(C(=O)NCC(O)c2ccc(Cl)cc2)c1N +Cc1oc2ncn3nc(C(C)NC(=O)C4CCOCC4)nc3c2c1C +NC(=O)CCn1c(=O)n(CCC(N)=O)c2cnccc21 +CC(C)(C)n1ncc2c(=O)n(CC(=O)Nc3ccc(F)cc3)cnc21 +COc1ccc(N)cc1C(=O)OCCC(C)(C)OC +O=C(Nc1ccccn1)N1CCC(C(O)c2ccccc2)CC1 +O=C(Cc1cccc(F)c1F)NCC(=O)N1CCCCC1 +CCC(C)(C)C(=O)Nc1cc(N2CCCS2(=O)=O)ccc1Cl +CC(C)CC1NCCc2c(Br)cc(F)cc21 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(C)cc2)cc1 +COc1ccc(S(=O)(=O)Nc2ccc(OC)cc2OC)cc1 +CCNC(=O)CCCc1nc(-c2cnn3c(C)cc(C)nc23)no1 +CSc1nc2nc(C)c3c(=O)n(C4CCCC4)ccc3n2n1 +CCOC(=O)c1coc(N2CCC(Oc3ccccc3OC)CC2)n1 +NS(=O)(=O)c1ccc(N2CCCC(CCO)C2)cc1 +Cc1cc(C(=O)NCc2ccnc(-n3cccn3)c2)on1 +CNc1snc(C)c1C(=O)N(C)CC1CCCO1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)Nc1ccccc1 +CC(=O)N1Cc2ccccc2CC1C(=O)Nc1ccn(C)n1 +COC(=O)CN(Cc1ccc(Cl)cc1)Cc1cccnc1C +O=C(CN1CCN(C(=O)c2cc3c(s2)CCC3)CC1)N1CCCC1 +CN(CCc1ccc(F)cc1)C(=O)Cn1cnc2c(cnn2C)c1=O +Cc1ncsc1C(=O)NC1CCN(c2ccccc2)C1=O +O=C(Cn1nc2nc(N3CCCC3)ccn2c1=O)NC1CCCCC1 +Cc1nc(C)c(C(=O)NCC(=O)Nc2nccs2)s1 +O=C(Cc1cn2ccccc2n1)Nc1c[nH]cc(Br)c1=O +Cc1cc(CNC(=O)CC2CC3CCC2C3)c(C)o1 +CC(=O)NCc1ccc(C(=O)NCC2(c3cccs3)CCCC2)o1 +Cc1cccc(C(C)C)c1NC(=O)NCc1cccnc1 +COC(=O)c1cnc(OC(C)C)nc1-c1ccccc1Cl +CCC1Oc2cc(O)ccc2N(CC(=O)N(CC)CC)C1=O +COc1ccc2[nH]c(CNC(=O)c3cc(C)n[nH]3)cc2c1 +COc1cc(=O)[nH]c(SCC(=O)Nc2cccc(C)c2)n1 +Cc1ccc(NC(=O)Cn2nnnc2-c2nonc2N)c(C)c1 +CC(C)C(C)(C#N)NC(=O)CNc1cc(F)ccc1F +N#Cc1c(F)cccc1Sc1nnc(-c2cccnc2)n1C1CC1 +O=C(Nc1cccc(C(F)(F)F)c1)c1ccsc1 +Cc1occc1C(=O)Nc1cc(NC(=O)N(C)CCC#N)ccc1F +CC1CCCC1NC(=O)C1COc2ccc(F)cc2C1 +COCCn1c(=O)c(C#N)cc2c(=O)n3ccccc3nc21 +OC1(C#Cc2ccccc2)c2ccccc2-c2ncccc21 +c1ccc2c(CNCc3ccnc(-n4cccn4)c3)csc2c1 +O=C(CSc1cccnn1)Nc1cc(N2CCOCC2)ncn1 +CC(C)c1cc(=O)[nH]c2cc(NC(=O)c3ccsc3)ccc12 +O=C(NCc1ccccn1)c1cn(-c2cccc(F)c2)nn1 +CCCn1c(C(=O)NCC2CC2)cc2sccc21 +CCOCc1cccc(NC(=O)NC(C)C(=O)N2CCCCC2)c1 +CCc1ccc(C(=O)NC(C)c2nnc3n2CCC3)s1 +O=C(c1cn(-c2ccccc2)nc1-c1cccnc1)N1CCOCC1 +COc1cc(CN(C)Cc2nccn2C)c(SC)cc1OC +COc1ccc(CC2(c3ccc(F)cc3)NC(N)=NC2=O)cc1 +CCOC(=O)c1cn(C2CC2)c2cccc(N)c2c1=O +Cc1ccc(C(C)(C)C)cc1SCC(=O)N1CCCC(C(N)=O)C1 +CCN1CCc2ccc(NC(=O)c3c(C)noc3C(C)C)cc21 +Cc1cccc(-c2nn3c(=O)cc(-c4cccnc4)[nH]c3c2C)c1 +O=C(Nc1nc[nH]n1)c1sc2cccc(Cl)c2c1Cl +Cc1nc(C)c(C(C)N(C)C(=O)Cc2cccc(F)c2F)s1 +Cc1nccc(NC2CN(C(=O)CN3CCOCC3)CC2C(C)C)n1 +CN(C(=O)c1ccncc1Cl)c1ccc2c(c1)OCO2 +N#Cc1cccc(CNc2c(F)cc(N)cc2F)c1 +Cc1ccc(C(CNC(=O)c2cnn(C)c2C)N2CCOCC2)o1 +Cn1cccc1C(=O)N1CCC2(CC1)OCCO2 +CCSc1ccc(C(=O)Nc2sccc2C(=O)NC)cc1 +COC(=O)C(CC(C)C)NS(=O)(=O)c1ccc(C)s1 +O=S(=O)(c1cccc(-c2ccccc2)c1)N1Cc2cncnc2C1 +CCC(O)c1ccccc1OCc1cnc(C)s1 +CC(=O)c1cccc(NC(=O)c2sc(C)nc2C)c1 +CCC(CC)NC(=O)C(C)Sc1n[nH]c(N)n1 +Cc1noc(C2CCC3(CCN(S(C)(=O)=O)CC3)O2)n1 +CC(c1ccccc1)N(C)C(=O)CNc1cc(F)cc(F)c1 +O=C(NCc1nc(C2CC2)no1)c1ccnc(-n2ccnc2)c1 +Brc1ccc(OCCOC2CCOCC2)cc1 +CCOC(=O)CN(C(=O)c1ccc(-n2ccnn2)cc1)C1CCCC1 +Cc1ccc(CN(C)C(=O)CCCSc2ccccc2)o1 +Cc1cccc(CN2CCC(OCC3CC3)C2Cc2ccncc2)n1 +Cc1ccc(OC(=O)CCc2nc(C(C)C)no2)cc1C +N#Cc1ccc(-c2noc(C3CC(=O)Nc4ccccc43)n2)nc1 +COc1cccc(-c2cc(CNC(=O)c3ccc(=O)[nH]c3)no2)c1 +COc1ccc(NC(=O)CCn2c(=O)oc3ccccc32)c(OC)c1 +C#CCN(Cc1ccc(C)cc1)C(=O)c1cn(C)nc1-c1cccnc1 +COc1cc(CNC(=O)Cc2cccs2)ccc1C +CN(C)C(=O)N1CCC(C(=O)Oc2cccc(C(F)(F)F)c2)CC1 +Cc1cccc(NC(=O)C(C)n2c(CO)nc3ccccc32)c1C +CCOC(C)c1nccn1CC(=O)N1CCCCC1 +CN1C(=O)CCC2(CNC(=O)C3(c4ccccc4)CC3)CCCC12 +Cc1ncc(CNC(=O)c2ccc3c(c2)CCO3)s1 +CN(C)C(=O)C(N)c1cccc(Br)c1 +Cc1ccc(C)c(OCCC(=O)NC2c3ccccc3CC2O)c1 +CC(C)c1nccc(CN2CC(c3cccnc3)C2)n1 +CCC(C(=O)N(C)C)N(c1cccc(OC)c1)S(C)(=O)=O +CC(=O)NC(C)(C)c1noc(-c2cccc(-c3n[nH]c(C)n3)c2)n1 +COc1ccc(F)cc1NC(=O)NCC(=O)OC(C)(C)C +COCCN(Cc1cnc2ccsc2c1)CC(F)F +COC(C)C(=O)N(c1cccc(F)c1)C1CCOCC1 +O=C(CCC(=O)c1ccc(Br)cc1)NCCCO +CC1CC1C(=O)Nc1ccc(Cl)c(S(N)(=O)=O)c1 +CC(C)NC(=O)NCCc1ccc(NC(=O)OC(C)(C)C)cc1 +Cc1ccc(CNC(=O)NCc2ccc(C(=O)N(C)C)cc2)s1 +CC(NCC(=O)N(C(C)C)C(C)C)c1ccc(Cl)cc1 +CCN(CC)C(=O)C1CCCN1C(=O)c1ccccc1C +Cc1ccc(O)c(C(=O)Nc2cnn(CC(=O)NC3CC3)c2)c1 +Cc1cc(CC2COCC2NC(=O)c2c(C)cc(C)[nH]c2=O)on1 +Cc1cnc(C(=O)Nc2cc(-c3ccccc3)nn2C(C)C)cn1 +CCOc1cc2c(cc1O)C(c1cncc(F)c1)NCC2 +CCOC(=O)CCC(=O)Nc1cc(C(=O)N(C)C)cn(C)c1=O +CC1CC(CC(C)C(=O)Nc2nncs2)C(=O)O1 +O=C(c1ccccc1)N(Cc1ccco1)c1ccccn1 +CC(C)CCC(=O)N1CCN(C(=O)NCCc2ccccn2)CC1 +CCC(NC(=O)CN(C)c1cnccn1)C(C)C +Cc1nn(C)c(C)c1CN(CC(C)C)C(=O)C1CC1 +Cc1cc(C)n(Cc2cccc(F)c2)c(=O)c1C#N +CC(C)c1ncc(CN(C)C2CCN(c3ccccc3)C2=O)s1 +CCC(C)n1nccc1NC(=O)C1CC1(Cl)Cl +Cc1cc(NC(=O)c2cc(C3CC3)on2)ccc1Oc1cccnc1 +COc1ccc(C)cc1NC(=O)COc1cccc(-n2ccnc2)c1 +C=CCOc1ccccc1CNC(=O)c1cnn(-c2ccncc2)c1C +CCc1ccc(OC(C)C(=O)Nc2ccc3c(c2)NC(=O)CO3)cc1 +Cc1ccc(N2CCN(CC(=O)NCC(=O)NC3CC3)C2=O)cc1 +CCOCC(=O)Nc1ccc(S(N)(=O)=O)cc1 +C#CCNC(=O)c1ccc(OC)c(Br)c1 +CCc1ccc(CNc2ccc(-n3cc(CO)nn3)cc2)cc1 +Cc1[nH]c2cc(Cl)c(Cl)cc2c(=O)c1CCC#N +NC(=O)c1cccc(COc2cccc(Br)c2)c1 +Clc1cccc(OCc2nc3ncccc3[nH]2)c1 +Cc1noc(C)c1CN(C)C(=O)C1Cc2cc(F)ccc2O1 +Cc1ccc(C(CNC(=O)c2ccc(Cl)cc2)OCCO)cc1 +CCN(CC(F)(F)F)C(=O)c1noc2c1CCCC2 +COc1ccc(CN2CCC(C(F)(F)F)(C(F)(F)F)C2)cc1O +O=C(COc1ccc(Br)cc1F)NC1CCCNC1=O +CC1CCC(NC(=O)c2ccc3c(=O)n4c(nc3c2)CCCC4)CC1 +O=C(NCc1ccsc1)c1nc2ccccc2c(=O)[nH]1 +CC(C)C(=O)N1CCC(Nc2ncnc3ccccc23)CC1 +CCOc1ccc(COC(=O)c2cccn2C)cc1OC +CCOC(=O)c1ccc(-n2nc3cc(C)c(N)cc3n2)cc1 +COc1ccc(-c2cc3cccnc3n2CC(=O)NC(C)C)cc1 +Cc1ccc(C)c(S(=O)(=O)NCC2CCCO2)c1 +CC(C)c1nc2cc(S(C)(=O)=O)ccc2n1C +Cc1cccc(C(=O)NC(C)c2cccc3ccccc23)n1 +Cc1noc(C)c1C(=O)NC(C)c1ccc2c(c1)CCCC2 +Cc1cc(NC(=O)CCn2ccccc2=O)ccc1-n1cnnn1 +O=C(NCCc1c[nH]c2ccccc12)c1cccnc1 +CC(C)N(C(C)C)S(=O)(=O)c1ccc(N2CCCCCC2)nc1 +CCC(NC(=O)c1cn2cc(C)ccc2n1)c1cn2cccnc2n1 +CCOC(=O)C1CCCN(C(=O)CCNC(=O)c2cccs2)C1 +CC(C)(C)OC(=O)CNC(=O)COc1ccc2ccccc2c1 +N#Cc1ccc(N2CCCC(NC(=O)Nc3ccccc3)C2)c(F)c1 +O=C1CCCN1c1ccc(Oc2ncnc3sccc23)cc1 +CN(CCC#N)C(=O)CSc1nc(-c2ccccc2F)n[nH]1 +COc1ccc(C2CC(=O)NC3=NC(N)=NC(=O)C32)cc1 +Cc1c(CN2CCOCC2C2CC2)cc(C#N)n1C +Cc1ccc(C(=O)N2CCC(Nc3cccnn3)CC2)o1 +COc1ccccc1C(=O)N1CC(=O)c2ccccc2S1(=O)=O +CCOC(=O)N1CCN(C(=O)Nc2ccc(Cl)cc2Cl)CC1 +CCC(NC(=O)c1ccc2[nH]cnc2c1)c1cc(F)ccc1F +CC(C)CC1COCCN1C(=O)NCc1ncn(C)n1 +CC(C)(C)c1cnc(CNC(=O)NCC(C)(O)c2ccc(F)cc2)o1 +Cc1ccc(NC(=O)NCCCOCC2CCCO2)cc1F +Cc1nn(C)c(C)c1-c1cc(C(=O)NCCc2cccs2)[nH]n1 +COC(=O)C1CCCCN1Cc1cnc2ccsc2c1 +Cc1cc(=O)[nH]c(CCn2ccnc2-c2cc3ccccc3s2)n1 +Cc1ocnc1C(=O)NC(C)c1cccc(N2CCCC2=O)c1 +O=C(COC(=O)c1ccccc1Cl)NCc1cccs1 +COc1ccccc1C(C)NC(=O)c1ccc2c(c1)OCO2 +COC(=O)c1ccc(NC(=O)C2CCCN(S(C)(=O)=O)C2)cc1 +CCc1cnc(C(C)NC(=O)c2ccnc(OC3CCC3)c2)s1 +CCC1CCCCN1C(=O)C(C)Nc1cnn(CC)c1 +COc1ccc(-c2nc3cc4c(cc3c(=O)o2)OCCO4)c(OC)c1 +Cc1cc(C(=O)Nc2ccc(C(=O)NC3CC3)cc2)c(C)n1C(C)C +CCC(C#N)NC(=O)c1nc(SC)n2ccccc12 +Cc1cnc(NC(=O)NCc2ccc3c(c2)OCO3)s1 +Cc1cc(NC(=O)CSc2ccc(O)cc2)n(C(C)(C)C)n1 +COC(=O)c1ccc2c(c1)nc(N)n2-c1ncccc1C#N +C#CCNC(=O)NC(C)c1sc(-c2ccc(OC)cc2)nc1C +COc1ccc(OC)c2sc(NCc3ccccn3)nc12 +O=C(NCCc1ccccc1)C1CN(C(=O)c2cccs2)C1 +CC(=O)c1cccc(OCC(=O)NCc2ccc(Cl)cc2)c1 +Cc1c(C#N)c(N)n(-c2ccc(F)cc2Br)c1C +CC(C#N)(NC(=O)CSc1ccc(N)nc1)C1CC1 +CNC(=O)NCC(=O)NC(CC(C)C)c1ccc(Cl)cc1 +Cc1cc(C)c(NC(=O)c2ccc(N)nn2)c(C)c1 +CC(=O)Oc1ccc(C)cc1NC(=O)c1ccccc1F +O=C(Nc1ccc2c(c1)COC2)C1CCCN1C(=O)c1ccco1 +O=C(NC1(c2ccccc2)CCCC1)c1cccc(-n2cnnn2)c1 +CCC(NC(=O)c1ccccc1SC(F)F)C1CCCO1 +CNc1ncccc1S(=O)(=O)N(CCC#N)C(C)C +O=C(c1cccnc1)N1CCCN(C(=O)c2cccc(Cl)c2)CC1 +CC1Oc2ccc(NC(=O)CCc3cccnc3)cc2NC1=O +Cc1cc(N)c2nc(NC(=O)c3ccc(N)cc3)sc2c1 +CCn1cc(C(=O)OCC(=O)NCC2CC2)c(=O)c2ccc(C)nc21 +OCc1c(OCC(F)(F)C(F)F)nc2sccn12 +COc1ccc(NC(=O)c2cccc(C)c2)cc1S(=O)(=O)N(C)C +Cc1oc(=O)n(C(C)C(=O)NC2CCCC2)c1C +COc1ccc(C(=O)CSc2nc(N)cc(=O)[nH]2)cc1OC +Cc1ccc(NC(=O)CCn2cnc3sccc3c2=O)c(C)c1 +CS(=O)(=O)c1ccc2nc(NC(=O)c3ccno3)sc2c1 +COC(=O)C(C)Oc1ccc(-c2nccs2)cc1N +CC(CCc1ccc(O)cc1)NC(=O)Cc1cccnc1 +CC(C)(CNS(=O)(=O)c1cn[nH]c1)c1ccccc1 +CC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccccc2C)cc1 +COc1cc(OC)cc(C(=O)Nc2ccccc2N2CCOC2=O)c1 +O=C(CNC(=O)c1cc(F)cc(F)c1)Nc1nc2ccccc2s1 +Cn1nccc1CNC(=O)Nc1cnn(CC(N)=O)c1 +CC(=O)NCCn1cc(-c2ccc(C(F)(F)F)cc2)nn1 +CCN(CC(C)C#N)C(=O)CN1CCOC(c2ccccc2)C1 +N#CC(C(=O)c1ccco1)c1nc2ccccc2o1 +N#Cc1ccc(Sc2nc3ccccc3o2)cc1C#N +CC(C)NC(=O)C(C)NC(=O)OCc1ccccc1 +CCn1c(-c2cccc(OC(C)C)c2)ccc(C(C)=O)c1=O +Cn1ccnc1C(=O)N1CC2(C)CC1CC(C)(C)C2 +O=C(NCC(=O)N1CCCC1)NC1(c2ccccc2)CCCCC1 +C#CCNC(=O)C1CCN1S(=O)(=O)c1ccccc1 +COc1cccc(CNC(=O)N2CCC(C)CC2C)c1OC +COc1ccc(C(=O)NCc2ccc(C)cc2)c(O)c1 +Cc1cnc(C(=O)N2CCCC(Cc3nc4ccccc4[nH]3)C2)cn1 +COc1cccc(C(=O)NC(C)c2nc(C3CCCC3)no2)c1F +CC(C)c1nc(-c2cc(NCc3cccnc3)nc3[nH]ccc23)n[nH]1 +COC(=O)C(C)CN(C)C(=O)CCn1ccnc1 +Cc1cccnc1CN1CCN(C(=O)c2ccc3nccnc3c2)CC1 +COc1cc2nc(C)n(CCNC(=O)C3CC3)c(=O)c2cc1OC +CCC1CN(C(=O)c2ccc(Cl)c(S(=O)(=O)NC)c2)CCO1 +CC1CCCC(NC(=O)c2ccnc(-n3ccnc3)c2)C1C +NC(=O)c1cnc(NC(=O)Cn2cnc3ccc(F)cc3c2=O)s1 +COCC1(C(=O)N2CCC3(CC2)Nc2ccccc2NC3=O)CCC1 +Cc1sc(=O)n(CC(=O)NC(C)(C)C)c1-c1ccc(F)cc1 +COc1ccc(NC(=O)C(C)NC(=O)c2ccc(Cl)cc2)cn1 +COCCn1nc(C)c(CNc2ncnc3cc(Cl)ccc23)c1C +CC(=O)Nc1cc(-c2nc(-c3ccc4oc(C)nc4c3)no2)ccc1C +Cn1cc(CC(=O)Nc2ccc(CNC(N)=O)cc2)c2ccccc21 +Cc1ccccc1CNC(=O)Nc1ccc2c(c1)oc(=O)n2C +COc1ccccc1-n1cnc2cc(C(=O)NCCO)ccc2c1=O +Cc1ccc(C)c(NC(=O)CSc2nc(N)c(C#N)cc2C#N)c1 +O=C(NC1CC1)c1cccc(NS(=O)(=O)c2ccc(F)cc2)c1 +CC(C)c1c(C(=O)N(C)C2CC2)cnn1-c1cccc(Cl)c1 +COc1cccc(C2=CCN(S(=O)(=O)c3ccccc3)CC2)c1 +CCCCn1nccc1NC(=O)Cc1c[nH]c2c(C)cccc12 +C=C(C)CN(CC)C(=O)CN1C(C)COCC1C +Cc1nn(C)cc1-c1nn2c(-c3cccnc3)nnc2s1 +Cc1nc(-c2ccc(Cl)c(Cl)c2)[nH]c(=O)c1CCO +CN(C(=O)CCn1ncc(=O)c2ccccc21)C1CC1 +O=C(NC1CCCCCC1)C(O)c1ccc2c(c1)OCCO2 +Cc1cc2c(cc1S(=O)(=O)NCc1ccccc1)OCC(=O)N2 +CCCc1nnc(NCc2nc3cc(Cl)ccc3n2C)o1 +Cc1ccc(Cl)cc1NC(=O)C1CN(C(=O)c2cnccn2)C1 +Cc1cc(NC(=O)CNC(C)(C)c2ccc3c(c2)OCCO3)no1 +CC(C)c1nnc2n1CCN(C(=O)c1ccc3c(c1)CCO3)CC2 +CCCCC(=O)Nc1cc(C(=O)N2CCCC2)cn(C)c1=O +Cc1nc(CN2CCN(C(C)C(=O)N3CCCC3)CC2)cs1 +CCC(NC(=O)NC(C)CCC1CCCO1)c1nc(C)cs1 +Cc1cccc(C(C)C)c1NC(=O)c1cccc(N2CCCC2=O)c1 +Cc1cccnc1NC(=O)c1coc(-c2ccccc2)n1 +Cc1nc(C(C)(C)NC(=O)c2cc3cc(F)ccc3o2)sc1C +CCc1ccc(N2CC3(OCC4OC(C)(C)OC4C3=O)OC2=O)cc1 +CC(C)c1nc(CCN2Cc3ncccc3C2=O)no1 +Cc1cc(C)c2c(CC(=O)Nc3ccccn3)coc2c1 +CCCc1csc(NC(=O)Cc2cccc(O)c2)n1 +O=C(Cn1cnc2sccc2c1=O)Nc1cc(Cl)ccc1F +NC(=O)c1cccc2c1CCCN2C(=O)c1cc(=O)[nH]c2ccccc12 +COCCN(Cc1ccco1)C(=O)Nc1ccc(C#N)c(Cl)c1 +Cc1nn(Cc2ccc(Cl)cc2)c(C)c1-n1cnnn1 +COC(=O)c1cc(CSc2nc(N)cc(N)n2)c(C)s1 +CCCN1C(=O)C(Cc2nc3ccccc3c(=O)n2C)c2ccccc21 +Cc1cc(C)nc(NC(=O)c2ccc(Cn3cccn3)cc2)n1 +COC(=O)c1ccc(-c2ccc(Cl)c(N)c2)o1 +O=C(Cc1ccc2c(c1)CCO2)NCCc1ccccc1 +O=C(Nc1ccc(F)cc1)c1cc(-c2ccccc2)no1 +COC(=O)C(Cc1ccc(O)cc1)NC(=O)c1ccc(C#N)cc1 +Cc1ccn2cc(C(=O)Nc3cc4c(cc3Cl)OCO4)nc2c1 +Cc1ccc(C2NCCc3c2cc(F)c(Cl)c3F)cn1 +CN(n1cnc2ccccc2c1=O)S(=O)(=O)c1ccc(Cl)cc1 +CC(O)(CNC(=O)CSc1ccc(F)cc1)c1cccs1 +CCN(CCCNc1ccc(C#N)cn1)S(C)(=O)=O +CCC(C)NC(=O)N1CCc2c(c(-c3nc(C4CC4)no3)nn2C)C1 +Cc1cc(-c2ccccc2CN2CCOCC2)c(=O)[nH]c1C +Cc1ccc(C(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)o1 +c1cncc(CN2CCc3nc4ccncc4cc3C2)c1 +CCn1c(NCCO)nc2sc3c(c2c1=O)CCCC3 +Cc1cc(C(=O)Nc2ccc(-n3ccnc3)c(F)c2)c(C)n1C1CC1 +Nn1c(SC2CCOC2=O)nnc1C(F)(F)F +COC(=O)C(C)NC(=O)CC1NC(=O)c2ccccc2N=C1O +Cc1c(C(=O)N(C2CC2)C(C)C(C)C)cnn1-c1ccncc1 +NC(=O)CCCNS(=O)(=O)c1cc(N)cc(F)c1 +COc1cc(C#N)ccc1CN(C)CCc1ccncc1 +CN(Cc1cccs1)C(=O)CN1C(=O)c2cccc3cccc1c23 +CC(Cc1ccc(Cl)cc1)N(C)C(=O)c1ccc[nH]c1=O +COc1ccc(CN2CCC(c3nc(-c4cccs4)no3)C2)cc1 +COc1cccc(CCC(=O)Nc2nnc(-c3ccccn3)[nH]2)c1 +NC(C(=O)Nc1ccc(Oc2ccccc2)cc1)c1ccccc1 +COC(=O)C(C#N)CC1N=C(C)Cc2ccccc21 +Cc1nc(CCNC(=O)N2CCOC(C)(c3cnn(C)c3)C2)cs1 +CCOc1ccc(NC(=O)NCC2CCC2)cc1C +COc1ccccc1NC(=O)NCC1CC(=O)N(c2ccccc2)C1 +CC(C)Oc1ccccc1NC(=O)c1ccc(OCC(F)F)nc1 +CCOc1ccc(NC(=O)c2cn3nc(OCC)ccc3n2)cc1 +CCCCC(=O)NCCN1CCN(C(=O)OC)CC1 +CCc1ccccc1NC(=O)c1cc2n(n1)CCCC2 +O=C(CN1CCN(c2ncccn2)CC1)N(C1=CCCCC1)C1CC1 +O=C(NCc1ccco1)c1cccc(Cn2ccccc2=O)c1 +CC(=O)Nc1cccc2c1CCN(Cc1ccc(-n3ccnc3)cc1)C2 +O=C(Nc1ccsc1C(=O)NCc1ccncc1)c1ccccc1 +CC(NC(=O)c1cc(Cl)ccn1)c1ccc(C#N)cc1 +O=C(NC1CC1)C1CCN(c2cc(C(F)(F)F)ccn2)CC1 +CC(=O)c1ccc(C)c(NC(=O)Cc2ccccc2)c1 +O=C(OCc1ccccc1)C1CCCN1C(=O)c1cc(F)cc(F)c1 +COCc1ccc(C(=O)N2CCC(Oc3cccc(F)c3)CC2)o1 +COc1ccc(CN(C)C(=O)C2COc3ccccc3O2)c(OC)c1 +NC(=O)Nc1ccc(NC(=O)CCc2ccc(-c3ccccc3)o2)cc1 +Fc1ccc(CSc2nnc3n2CCCN3)cc1 +COc1ncccc1CN(C)S(=O)(=O)c1c(C)noc1C +O=C1CCN(c2ccccc2Br)C1=O +O=C(NCc1ccccc1F)c1snnc1-c1ccccc1 +O=C(c1cc2cnc3[nH]ccc3c2s1)N1CCc2ccccc2C1 +O=C(NCC1CC1)C1CCCN(C(=O)Nc2cccc(Cl)c2)C1 +CC(=O)Nc1cc(OC(F)F)ccc1Br +CCC(C)(COc1ncccc1Cl)NC(=O)Nc1nccs1 +COC(=O)c1ccc(NC(=O)c2cccc(N)c2)cc1 +O=C(NC1CCCCC1)N1CCn2c(cccc2=O)C1 +CCN(CC)C(=O)c1cnc(-c2ccc(F)cc2)nc1N +COc1cccc(Cn2cccc2-c2nc(C)no2)c1 +COc1ccc(NC(=O)Nc2cccc(NC(C)=O)c2C)cc1 +O=C(NCc1cccc(OCC2CCC2)c1)c1cc2ccoc2cn1 +COc1cc(CCC(=O)Nc2c(C)cccc2C)cc(OC)c1OC +Cc1ncc(C(=O)N(C)Cc2n[nH]c3c2CCCCC3)c(C)n1 +Cc1cc(Sc2ccc(N)cc2C(N)=O)n(C)n1 +COCCNC(=O)c1cc(-c2cccnc2)n(-c2ccc(F)cc2)n1 +Cn1cc(C(N)=O)cc1C(=O)Nc1nc(-c2cccc(F)c2)cs1 +CC(C)CCN(CCC#N)C(=O)Cc1c[nH]c2cc(F)ccc12 +Cc1cc2c(N3CCC(C(N)=O)CC3)ncnc2s1 +Cc1nc(C)c(C(=O)N2CCCSc3ccccc32)o1 +Cc1n[nH]c(C2CN(C(=O)Cc3cnn(C)c3)CCO2)n1 +CCOC(=O)C1=C(CC)N(C)C(=O)NC1c1ccco1 +C#CCN(Cc1ccccc1)C(=O)c1ccc(NC(=O)C2CCC2)cc1 +O=C(C1CC=CC1)N1CCCn2c(nc(CN3CCCC3)cc2=O)C1 +CNS(=O)(=O)c1ccc(-c2nc(-c3ccncc3)no2)o1 +CC(C)CCN1CC2=C(C1=O)C(c1ccccc1)NC(=O)N2 +CCCC(=O)N1CCCCC1C(=O)NCc1nc(-c2ccco2)n[nH]1 +O=C(NCC(=O)N1CCOCC1)c1cc2sccn2c1 +C=CCNC(=O)C1CC(=O)N(c2cc(C)ccc2OC)C1 +COCC(=O)N1CCCc2ccc(NC(=O)c3cccc(C#N)c3)cc21 +CCn1nccc1CN(C)C(=O)c1snnc1C +O=C(NCC1CCCO1)c1noc2c1COc1ccccc1-2 +CCC1CCCCN1C(=O)c1cn(CC)c2cccc(N)c2c1=O +CCOc1ccccc1CN(C)C(=O)NCCC(=O)N1CCCCC1 +CNC(=O)c1ccc(NC(=O)c2ccccc2Cl)cc1 +O=C(COc1cccc2ccccc12)Nc1ccncc1 +CCOC(=O)Nc1ccc(NC(=O)NCc2cccs2)cc1 +CNC(=O)NCC(=O)Nc1ccc(OC(C)c2ccccc2)cc1C +COC(=O)C1=C(C)NC(=O)NC1c1ccncc1F +O=C(NCc1ccco1)C1CC2CN(c3nncs3)CC1O2 +CS(=O)(=O)c1cccc(NC(=O)c2ccc(C(F)(F)F)nc2)c1 +CCOC(=O)C1(NC(=O)c2sccc2C)CCCC1 +Cc1c(NC(=O)c2cc(-c3cccs3)on2)cnn1C +COCCN1CCCC2(CCN(C(=O)Cc3cccc(C)c3)C2)C1=O +CC(C(N)=O)c1cc(Br)c2nncn2c1 +CCOc1ccc(C(=O)Nc2cc(Cl)ccc2Cl)nn1 +O=C(CCS(=O)(=O)c1cccc2nonc12)NCc1ccccc1 +COc1cc(NC(=O)c2ccc(F)c(C)c2)c(C(N)=O)cc1OC +CC(=O)N1CCCC1C(=O)NCC1(c2ccccc2C)CCOCC1 +CCCCN(CC(N)=O)C(=O)Cc1ccc(F)cc1F +Cc1cc(C(=O)Cn2nnc3ccccc32)c(C)n1C +CCNC(=O)C1CCCN(S(=O)(=O)c2ccc(CC)s2)C1 +Cc1ccccc1NCC(=O)N(C)Cc1ccccc1F +Cc1ccc(C(C)C)c(OC(=O)Cc2csc(C)n2)c1 +O=C1N=C(Nc2cccc(Cl)c2)N2Cc3ccccc3CC12 +COCCCNC(=O)NCCc1c[nH]c2ccccc12 +Cn1nc(CNC(=O)Nc2c(F)cccc2F)c2ccccc2c1=O +COCC12CCOC1CCN(C(=O)c1ccc(C)c(C)c1)C2 +CC(C)NC(=O)c1ccnc(-c2ccc(O)cc2)c1 +Cc1cccc(-n2c(=O)c3c(c4cc(C)ccc4n3C)n(C)c2=O)c1 +Nc1cccc(C(=O)Nc2ccccc2Br)n1 +Cc1oc2ncnc(N3CCCCC3)c2c1C(=O)N1CCC(C)CC1 +CCn1nc(C)c(CN(C)C(=O)c2ccnn2C)c1C +CC(C)c1nc2cc(C(=O)N3CCCCC3c3cccnc3)ccc2o1 +COc1ncccc1N(C)C(=O)c1scnc1C1CCCC1 +CC(CNC(=O)NCCn1c(=O)oc2ccccc21)Cn1cccn1 +Cc1cccc(CC(=O)Nc2ccc3c(c2)COC3)c1 +Cc1cccc(C)c1NC(=O)CN(C)c1ccc(C(=O)N(C)C)cn1 +Cc1ccccc1Cn1ccc(=O)n(CC(=O)NCC(C)C)c1=O +COc1c(C)cnc(CSc2nnc(C)s2)c1C +CCN1C(=O)C(O)(CC(=O)c2ccc3c(c2)OCO3)c2ccccc21 +CN(CC(=O)NCc1nnc2n1CCCC2)c1ncnc2[nH]cnc12 +COc1ccc(NC(C)=O)cc1NC(=O)C(C)(C)c1ccccc1 +NC(=O)c1ccsc1NC(=O)CCCSc1ccccc1 +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCCc1ccccc1 +CCCc1cc(C(=O)Nc2ccc(OC)cc2)n(C)n1 +Cc1ccc(-c2ccnc3nc(-c4ccncc4)nn23)cc1 +COCc1nn2c(=O)cc(C)[nH]c2c1-c1ccc(OC)cc1 +CCOC(=O)c1c(NC(=O)c2c(C)noc2C)sc(C)c1C +CC(C)(C)C(C#N)NC(=O)c1cccc(C(=O)N2CCCC2)n1 +COc1cc(C)c(C(=O)C(C#N)c2ccc(F)cn2)cc1OC +N#CCCN(CCC#N)S(=O)(=O)c1ccc(N)cc1 +CCOC(=O)CCN1CC(CC)Nc2ccccc21 +CC(C1CC1)N(Cc1ccccc1)C(=O)CSc1nncs1 +CC(C(=O)NCC1CCCO1)S(=O)(=O)c1ccc(Cl)cc1 +N#CCCCSc1nc(-c2cccs2)n[nH]1 +COC(=O)CCCCNC(=O)N1CCCCCC1c1ccncc1 +CC(NS(=O)(=O)N(C)C)c1cccc(N2CCCC2=O)c1 +Cc1csc(SC(C)C(=O)Nc2ccc3c(c2)CCC3)n1 +CC(=O)c1cccc(NC(=O)CCNC(=O)Cc2ccccc2)c1 +COC(=O)CCC(=O)c1oc2ccccc2c1-n1cccc1 +COCCc1cc(N)n(-c2ccc(Cl)cc2Cl)n1 +Cc1nccc(CNC(=O)CNC(=O)OC(C)(C)C)n1 +Cc1n[nH]c(SCSc2nc3ccccc3s2)n1 +Cc1noc(-c2ccc(C(=O)Nc3cc(C#N)cn3C(C)(C)C)cc2)n1 +CC(=O)c1cccc(NCC(=O)N2C(C)CCCC2C)c1 +CC(NC(=O)NCc1cccs1)C(=O)N1CCCCC1C +COC(=O)CCC1(O)Sc2ccccc2NC1=O +COc1ccc(C(=O)OCC(=O)c2ccc[nH]2)cc1F +O=C1CCCCN1Cc1cccc(OC(F)F)c1 +COCCN(Cc1cnn(C)c1)C(=O)c1ccc2nc(C)cn2c1 +Cc1ccncc1NC(=O)NCc1ccc2c(c1)OCCCO2 +O=C1Cc2cc(C(O)Cc3cccs3)cc(F)c2N1 +O=C(NCc1ccccn1)C1COC(=O)N1Cc1cccc(O)c1 +c1ccc(Cc2nc(Cn3nnc(-c4ccsc4)n3)cs2)cc1 +Cc1c(CNC(=O)Nc2ccccc2OC(C)(C)C)cnn1C +Cc1cc(C(C)NC(=O)N(CCO)C2CC2)cc(C)c1F +COc1ccc2c(c1)CCNC2c1ccc(C#N)cc1F +COc1cc(C#N)ccc1OC(=O)C1CC1(Cl)Cl +COc1c(F)ccc2c1CCNC2CNC(C)=O +CCOc1nccnc1NC1CCN(C(=O)c2cccs2)CC1 +CC(NS(=O)(=O)c1ccc(Cl)c(C#N)c1)C(N)=O +O=C(NCC(=O)N1CCc2ccccc2C1)NC1CC1 +CC(OC(=O)c1ccncc1)C(=O)Nc1ccc(Cl)cc1Cl +Cc1nnc(SCc2c(Cl)cccc2Cl)n1CC(N)=O +CN(Cc1ccccn1)C(=O)c1cnc(C2CCCO2)s1 +O=c1onc(-c2cccs2)n1CC1CCOCC1 +COCCOC1CCN(C(=O)c2cc3c(F)c(F)ccc3[nH]2)CC1 +Cc1nc(N)nc(COc2ccc(Cl)cc2)n1 +O=C(CCC1CCCC1)N1CCCC(c2nnc(C(F)(F)F)o2)C1 +Cc1cc(C)cc(C2(C(=O)Nc3cnn(C)c3)CC2)c1 +Cc1nn(C)cc1C(C)NC(=O)NC1C2CCOC2C12CCC2 +O=c1c(Cl)c(Cl)cnn1Cc1nc(-c2ccsc2)no1 +COCCNCc1c(Cl)cccc1C(F)(F)F +Cc1ccc(CCC2CCN(C(=O)C3CCC(=O)N3)CC2)cc1 +CC(C)CC1COCCN1C(=O)c1cc(F)c(F)c(F)c1 +CCOC(C)c1noc(CN2CCN(Cc3cccs3)CC2)n1 +Cc1cccc(NC(=O)COc2ccc3c(c2)OCO3)n1 +Cc1nc(CNC(=O)NCC(O)c2ccc(Cl)c(F)c2)no1 +COCCNS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +C=CCNc1nc(=O)c(Cc2ccc(OC)cc2)n[nH]1 +COC(=O)c1cc(CNC(=O)N2c3ccccc3CC2C)oc1C +CC(O)CC(C)CNC(=O)Nc1ccc(C(=O)NC2CC2)cc1 +CC(C)(C)NC(=O)CSc1ncnc2sc3c(c12)CCCC3 +Cc1noc(C)c1-c1ccc(S(=O)(=O)NC2CCC(C)CC2)cc1 +Cc1cc(-c2nnc(NC(=O)c3ccc4ccccc4c3)o2)c(C)o1 +C=CCNC(=O)c1cccc(S(=O)(=O)Nc2ccc(CC)cc2)c1 +O=C(c1ccc2[nH]ncc2c1)c1ccc(F)cc1F +Cc1ccnc(Nc2ncnc(NC(C)(C)C)c2N)c1 +CCOC(=O)c1c(C)nc(C)c(C(=O)OCC)c1-c1cccnc1 +CN(C)C(=O)CN(C)C(=O)c1cc(-c2ccccc2)nc2ccccc12 +COc1cc(OC)cc(-c2c(C#N)nnn2CCO)c1 +COc1ccc(OCCNC2OC(=O)c3ccccc32)cc1 +CCCC(=O)N1CCCC(C(=O)N(C)CC(=O)N(C)C)C1 +CCOC1CCC2C1OCCN2S(=O)(=O)c1cccnc1 +CC(=O)Nc1ccnn1CC1=CCCN(Cc2nc(C)cc(C)n2)C1 +CCc1nnc(NC(=O)c2cnn(-c3ccc(F)cc3)c2)[nH]1 +CC(C)c1csc(C2CCCN(C(=O)c3cc(Cl)c[nH]3)C2)n1 +CCOc1cc(NC(=O)N2CCCC3CCCC32)ccc1OC +CCC1CN(C(=O)c2cc(=O)[nH]c3ccccc23)CCO1 +CNC(=O)CNC(=O)c1cc2sccc2n1Cc1cccc(F)c1 +CC(c1c(N)n(C)c(=O)n(C)c1=O)c1c(N)n(C)c(=O)n(C)c1=O +CCOC(=O)NCCC(=O)N1CCC(c2ccc(O)cc2)CC1 +O=C(Cn1nnc2ccccc21)Nc1cc(-n2cncn2)ncn1 +COCCn1nc(C(=O)NCC2CCCc3ccccc32)ccc1=O +Cc1cc(NC(=O)Cn2c(=O)c(C#N)cn(C3CC3)c2=O)no1 +CC(C)C(C)(C#N)NC(=O)CSc1nncn1C +Cc1c(N)c(-c2ccc3c(c2)N(C)C(=O)CO3)nn1C +Cc1ccncc1NC(=O)NC1CCCN(c2ccccc2Cl)C1 +Cc1noc(C)c1CCC(=O)NC1CCN(S(C)(=O)=O)CC1 +CCOC(=O)c1c(C)[nH]c(C(=O)N(C)c2ccccc2)c1C +CCC(C)NC(=O)COc1ccc(F)c(Cl)c1 +CC(C)OC(=O)C1C2C=CC(C2)C1C(=O)NCc1ccccc1 +Cc1ccccc1N(CC(=O)Nc1nncs1)S(C)(=O)=O +O=C(CCN1CCOCC1)c1cccc2ccccc12 +CN(CCc1noc(-c2ccccc2)n1)C(=O)c1ccc(F)cc1 +CCS(=O)(=O)N1CCCc2ccc(NC(=O)c3ccccc3)cc21 +O=C(C1CCCc2[nH]ncc21)N(Cc1cccnc1)Cc1ccco1 +CCS(=O)(=O)N1CC2COCC2(COc2cccnc2)C1 +O=C(Oc1ccc(-n2cnnn2)cc1)C1(c2cccc(F)c2)CCC1 +Cc1cccc(C(=O)NC(C)c2ccc(S(N)(=O)=O)cc2)c1C +CC(C)(C)OC(=O)Nc1ccc(CC(=O)Nc2nncs2)cc1 +COc1ccc(C(O)CNc2ncccc2Cl)cc1OC +Cc1ccc(-n2nnc(-c3noc(-c4ccccc4)n3)c2C)cc1 +Cc1cccc(C(C)C)c1NC(=O)C1CC1(Cl)Cl +CCc1ccccc1NC(=O)NCC(O)c1ccco1 +COC(=O)CCC(=O)Nc1nc2c(C)cccc2s1 +Cc1nc(NC(=O)c2nnn(-c3cccc4ncccc34)c2C)n[nH]1 +O=C(NCc1cccnc1-c1ccc(F)cc1)C1CC1 +CCN(CC)C(=O)C(c1ccccc1)S(=O)(=O)c1ccc(O)cc1 +Nc1ccc2c(c1)NC(=O)C(Cc1ccccc1F)O2 +Cc1cc(C(=O)NCCc2cccnc2)c2nc3n(c2n1)CCCCC3 +Cc1nonc1CC(=O)N1CC(F)CC1CNC(=O)C1CCC1 +N#Cc1ccc(C(=O)OCc2nnc(-c3ccccc3)o2)cc1 +CSc1cccc(NC(=O)NCC2CCC2)c1 +COC(=O)C1C(c2ccc(Cl)cc2)c2c(O)n[nH]c2CC1(C)O +CCNC(=O)CN1CCN(C(=O)C(C)OC)CC1 +COc1cc(-c2ncccc2C(F)(F)F)cc(OC)c1OC +CCOc1ccc(CNn2nnnc2N)cc1OCC +COc1ccc(-c2ccccc2OC(C)C(N)=O)c(OC)c1 +CCc1nnc(NC(=O)c2nn(-c3cccc(C)c3)ccc2=O)s1 +CC(C)(C)OC(=O)NC1CCN(c2nccn3c(=O)[nH]nc23)C1 +CC1CC(C)CN(C(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)C1 +COc1cc(NC(=O)c2ccccc2N)c(OC)cc1Cl +CC1(C)C2CCC1(C)C(NC(=O)CCc1nc(-c3ccco3)no1)C2 +Cn1cc(NC(=O)c2coc3ccccc23)cc(Br)c1=O +O=C(Cc1cccc(F)c1)Nc1ccc(F)c(F)c1F +O=C(Cc1nnc(-c2cnccn2)o1)Nc1ccc(F)cc1Cl +COCCNc1ncc(Br)cc1Cl +CC(=O)Nc1cccc(-c2cc(C#N)nn2CC(N)=O)c1 +COC(=O)CNC(=O)c1ccc(NCc2cccc3ccccc23)cc1 +CCNC(=O)CCCC(O)c1cc(C)c(C)cc1OC +O=C(Nc1cccc(C(F)(F)F)c1)C(c1ccccc1)n1cnnn1 +Cc1ccc(F)cc1C(=O)Nc1cccc(CO)c1 +COc1ccc2c(c1)c(C(=O)NCc1ccco1)cn2C(C)C +Cc1ccnc(-n2c(CCCO)nc3ccccc32)c1 +COc1cc(CNC(=O)Nc2nc(C)cs2)ccc1O +C=CCCC(=O)N(C)Cc1ccccc1Br +Cc1csc(NC(=O)CN2CCCc3ccccc32)n1 +O=C(c1cccc(Cn2cccn2)c1)N1CCC(CO)C(O)C1 +CN(CCOc1cccc(Cl)c1)C(=O)NCCN1CCOCC1 +O=C(c1cccs1)N1CCOC(COc2ccc3c(c2)CCC3)C1 +c1ccc2c(NCCn3cccn3)nc(-c3ccncc3)nc2c1 +N#Cc1cccc(C(=O)Nc2ccc3c4c(c(=O)[nH]c3c2)CCC4)c1 +CCC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccccc2)cc1 +Cc1cccc(CN2CCOCC3(C2)CN(C)C(=O)CO3)n1 +CC1(C(=O)NCCOc2cccc(F)c2)CC1(Cl)Cl +C=CCNC(=O)CCCC(=O)c1ccc(C)c(C)c1 +Fc1cccc(CCNCc2cccc3c2OCCCO3)c1 +O=C(c1ccco1)N1CCN(C(=O)c2cc3ccccc3s2)CC1 +COc1ccc(NC(=O)c2cccc(NS(C)(=O)=O)c2)cn1 +O=C(NCCC(=O)N1CCCC1)NCc1cc2ccccc2o1 +O=C(Nc1cccnc1)c1ccc(-c2ccccc2CO)o1 +CC(OCc1ccccc1)C1CCCC(C)(C#N)O1 +O=C(NCc1cccc(COC2CCOCC2)c1)c1ccc(F)nc1 +Cn1nnnc1SCC(=O)c1ccc2c(c1)OCO2 +CC1CN(C(=O)c2cc3c(=O)n4ccccc4nc3s2)CC(C)O1 +CCOC(=O)c1cc(-c2ccc(OC)c(OC)c2)[nH]c1N +O=C(NCc1ccncc1)C1CC(=O)N(C2CCCCC2)C1 +CC(C)CC(NC(=O)Cc1cccnc1)c1ncnn1C +CN(CCOc1ccc(F)cc1)C(=O)Nc1ccc2c(c1)OCO2 +CCc1nc2nnc3c(=O)n(-c4cccc(O)c4)ccc3n2n1 +C=CCCCN(C)C(=O)Nc1ccc(C(=O)NC)c(Cl)c1 +O=C(NCc1ccc(Cl)cc1Cl)c1cn2ccccc2n1 +O=C(Cn1c(=O)nc2n1C(=O)N(c1ccccc1)C2)N1CCCC1 +COc1cc(C)c(Cl)cc1-c1cn[nH]c(=O)c1N +ClC1=NC2=NC=NC2C(N2CCN(c3cccc(Cl)c3)CC2)=N1 +O=c1ccccn1Cc1nnc(-c2cccc(Cl)c2)o1 +COC1CCCN(c2ccnc(C(=O)N3CCOCC3)c2)C1 +COc1ccccc1CC(=O)N1CC(C)c2ccccc21 +Cc1nn(C)c2cn(C(C)C(=O)NCc3cccnc3)nc12 +CCCC(C)C(=O)Nc1sc2c(c1C(N)=O)CCCC2 +CCN(C(=O)Nc1cc(OC)ccc1F)C(C)c1cccnc1 +Nn1c(SCC(=O)N2CCCCC2)nnc1-c1cccs1 +CN(Cc1ccc(C(=O)NC2CC2)cc1)c1cccc(F)c1C#N +CCc1nc(CN(C)C(=O)Cc2cn(C)c3ccccc23)cs1 +O=C(CN1CCc2cc(F)ccc2C1)NCc1cc(F)cc(F)c1 +Cc1ccc(S(=O)(=O)N(C)C)cc1NCc1ccccc1F +O=C(NCc1ccc(Cl)c(Cl)c1)c1ccc2ncccc2n1 +Cc1ccsc1CN(C)C(=O)c1cnc(C(C)C)nc1C +CC(C)(C)C(=O)COc1cccc(S(C)(=O)=O)c1 +COC(=O)c1ccc(N2CCCC2)c(NC(=O)c2occc2C)c1 +CCOc1cc(C)c(C(N)C(F)(F)F)cc1Cl +CC(NC(=O)CN(C)S(=O)(=O)c1cccnc1)c1cccs1 +COc1cc(CNC(=O)Cc2c(Cl)cccc2Cl)ccn1 +CN(C)c1ccc(C(=O)Nc2ccc3c(c2)CC(=O)N3)cc1 +Cc1cc(NCc2cc(-c3ccco3)on2)nc(-c2cccnc2)n1 +Cc1cccc(C(=O)N(C)c2ccc(F)c(F)c2)n1 +O=C(c1ccno1)N1CCOCC2(CCC(Cn3cncn3)O2)C1 +CCOC(=O)C1=C(C)N(CCO)C(=O)NC1c1ccccc1F +Cc1nnc(C2CCCN2C(=O)c2cc(C)c(C)cc2Cl)o1 +CCCn1nc(C)c(CN2CCN(c3nc(C)c(C)s3)CC2)c1C +COc1ccc(S(=O)(=O)NCc2ccc(-n3ccnc3)cc2)cc1 +COc1ccc(CNC(=O)Cc2cn(C)c3ncccc23)cc1 +O=C(CC1CCCO1)NCc1ccc(-c2ccc3c(c2)CCO3)cc1 +O=C(NCCc1cc(Cl)cc(Cl)c1)Nc1nncs1 +O=C(Cc1ccc(F)c(F)c1)N1CCC(n2ccnn2)CC1 +O=S(=O)(c1ccc(Cl)cc1)N1CCOCC1 +O=C1COC2CN(c3ncc(F)cn3)CC2N1CC1CC1 +CC(C)C(=O)NC(C)C(=O)Nc1ccc(F)c(Cl)c1 +O=C(CCn1ccccc1=O)NC1CCN(C(=O)c2ccoc2)CC1 +CCCC(=O)N(Cc1ccsc1)Cc1ccco1 +Cc1cccc(C(=O)OC(C)C(=O)NCc2ccc3c(c2)OCO3)c1 +CCc1ccc(NC(=O)c2cccn2C(C)C)cc1S(N)(=O)=O +COc1ccc(C(C)=O)cc1COC(=O)c1ccc(C#N)cc1 +Cc1csc(N2CCN(CC(O)Cn3cccn3)CC2C)n1 +COC(=O)C(C)NC(=O)NCc1cccn1Cc1cccc(F)c1 +Cc1ccc(Oc2nnnn2C)c(Br)c1 +Cc1cc(Cl)ccc1NC(=O)c1cn2cccnc2n1 +O=C(NCCC(=O)N1CCCC1)c1cccc2ccccc12 +COCNC(=O)C1CCCCN1C(=O)OC(C)(C)C +CC1CCCc2sc3nc(N4CCOCC4)n4ncnc4c3c21 +O=C(COc1cccc2c1CCC2=O)Nc1ccccc1Cl +Cc1nn(CC(=O)N2CCc3sccc3C2)c(C)c1CCO +COc1ccc(-c2cnnc(NCCc3cccnc3)n2)cc1 +CC(NC(=O)c1ccco1)C(=O)N(C)C(C)c1cccs1 +CCC(c1nc2c3ccccc3ncn2n1)n1nc(C)c(Cl)c1C +COC(=O)CC1CCCCN1C(=O)OCC(C)C +COc1ccccc1CNC(=O)C1CCN(c2cn[nH]c(=O)c2)CC1 +CCCCn1nnnc1CN(C)S(=O)(=O)c1ccc(F)cc1 +COc1ccc2nc(SCC(=O)N(C)c3ccccc3)[nH]c2c1 +COCCCNC(=O)c1c(N)n(C)c2ccccc2c1=O +COC(=O)c1c(C)[nH]c(C(=O)N2CCCC2c2cccs2)c1C +CC1(C)Cc2cccc(OCC(=O)NCC(C)(O)c3ccco3)c2O1 +CCC(C)NC(=O)C(C)NC(=O)NCc1cnn(C)c1 +CC(c1nc2c(s1)CCCC2)N1Cc2ncccc2C1=O +O=C1N(CCOc2ccccc2Cl)c2ccccc2C12OCCO2 +Cn1ncc2c1CCCC2NC(=O)c1cc2cc(F)ccc2[nH]1 +COc1ncccc1C(=O)NC(C)c1ccc2c(c1)NC(=O)CO2 +COc1ccc2c(c1)C(n1ncc(C#N)c1N)CCCO2 +CCN(C)C(=O)COc1ccccc1OCC(F)(F)F +CCC(C)C(NC(=O)CCC1CCCCC1)C(N)=O +COC(=O)c1sccc1Cn1cnc2cc(F)c(F)cc2c1=O +Cc1cc(C)n(CCCNC(=O)C2(c3ccccc3)CCC2)n1 +O=C(CCNC(=O)Nc1cccnc1)NC1CCCC1 +CCCCc1nc2cc3c(cc2n1CC#N)OCO3 +CCc1cc(S(N)(=O)=O)n(-c2ccc(OC)cc2)n1 +Cc1cc(C)n(Cc2ccc(C(=O)Nc3cccc4cccnc34)o2)n1 +CC(NC(=O)c1cccnc1-n1cncn1)c1ccccc1 +Cc1nc(-c2cc(NC(=O)c3cccs3)c(C)s2)no1 +COc1ccc(CC(=O)Nc2ccccc2N)cc1 +NC(=O)Cc1ccc(OCC(=O)Nc2nc3ccccc3s2)cc1 +Cc1cc2sc(NC(=O)COCC(F)(F)F)nc2s1 +COc1ccc(-c2csc(NC3CC3)n2)cc1C +COc1ccc(CN(C)Cc2nnc(C)n2C)cc1SC +Cc1cc(C(=O)N(C)Cc2cnn(C)c2)c2c(=O)[nH]n(C)c2n1 +CN(CC(=O)Nc1nc(-c2ccco2)cs1)S(C)(=O)=O +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)OCO3)cc1C +CN(C)C(=O)c1cccc(NCC(=O)N2CCCCC2)c1 +Cc1ccc(CN(CCC#N)Cc2ccccn2)c(Br)c1 +Cc1ccc(C(N)=O)c(OCc2csc(C)n2)c1 +Nc1ncn2nc(-c3cccc(Br)c3)ccc12 +O=C(CCC1CCCC1)NCC(=O)N1CCC(Nc2ccccc2)C1 +COc1c(C2CCCN2C(=O)C(C)c2cc(C)oc2C)c(C)nn1C +O=C(Cn1cnc2c(c1=O)CCCC2)NC1CCCC1 +Cc1nc(-c2ccccc2O)n(-c2ccccn2)n1 +CN(C(=O)c1ccc(S(=O)(=O)N2CCCC2)cc1)c1ccccc1 +CC(NC(=O)NCc1ncn(C)n1)c1nc(C2CCCCC2)no1 +C#CCNC(=O)N1CCCC(CNC(=O)C(C)(C)C)C1 +Cc1nc2cc(C(=O)N3CCCC3c3cnn(C)c3)ccc2n1C +Cc1noc(COc2ccc(NC(=O)c3ccc(C#N)cn3)cc2)n1 +Cc1cccc(NC(=O)c2cc(C)c3c(=O)n(C)c(=O)n(C)c3n2)n1 +CC1CCCCC1NC(=O)C(C)n1nnc(-c2ccccc2)n1 +O=C(NCCc1cccc(O)c1)c1cc2c(nc3sccn32)s1 +CCn1cc2c(n1)CN(Cc1cn(C)c3ccccc13)CC2COC +FC(F)(F)c1ccnc(Oc2cccc(-c3cn[nH]c3)c2)n1 +CCOC(=O)c1nnc(-c2ccccc2)nc1NC +CCCC(C)C(=O)N1CCN(c2ccccc2O)CC1 +Cc1n[nH]cc1CNC(=O)CCn1cnc2ccccc21 +O=C(NCc1ccc(Cl)cc1)c1ccccc1F +O=C(Nc1ncccc1O)c1ccc(Cn2cncn2)cc1 +O=C(c1cccs1)N1CCc2c(nc(N3CCCC3)[nH]c2=O)C1 +C#Cc1cccc(NC(=O)c2cn3c(C)cccc3n2)c1 +O=C(NCc1ccncc1)c1cnc2ccccc2c1C(F)(F)F +Cc1cc(CCCC(=O)N2CCC3(CC2)OCC(C)O3)c(C)s1 +Cc1ccc(N2CCC3C2CCN3C(=O)c2ccc(C)o2)nn1 +CC1CCCCN1C(=O)c1cc(-c2cccnc2)nc2ccccc12 +COc1ccc(CN2CCN(c3nc(C)c(C)s3)CC2)cc1O +CC(C)N1C(=O)C2(OCCO2)c2cc(Cl)ccc21 +CC(C)(C)N(CC(=O)Nc1ccc(F)cc1)C(=O)c1ccc(F)cn1 +CCCNC(=O)c1ccc(NC(=O)NC(C2CC2)C2CC2)cc1 +CC(CNC(=O)Nc1nnc(C2CC2)s1)N1CCOCC1 +CCn1cc(C#N)c(=O)n(CCOc2ccccc2OC)c1=O +COc1cccc(CN2CCN(C(=O)CC3CCCC3)CC2=O)c1 +COC(=O)CNC(=O)c1ccccc1Cc1ccccc1 +CCc1nnc(NC(=O)N(Cc2ccco2)Cc2cccs2)s1 +COc1ccc(C(=O)CCC(=O)Nc2cn(C)c(=O)cc2C)cc1 +CCOc1ccccc1NCc1cc2ccccc2[nH]c1=O +CN(Cc1ccc2c(c1)OCO2)c1ccc(N)c(F)c1 +COc1ccccc1C1CC1C(=O)NCc1cccc(NC(N)=O)c1 +CCC(=O)Nc1ccc(Cl)c(NC(=O)C2CC2c2ccco2)c1 +Cc1nc(C(=O)N2CCCC2)nn1-c1ccc(F)cc1 +CC(c1ccccc1)N(C)C(=O)c1ccc(NC(=O)c2ccco2)cc1 +Cc1cccc(C)c1NC(=O)COC(=O)c1cccc(Cl)c1 +CC(C)C(=O)c1ccccc1NC(=O)Cc1cccs1 +COc1ccc(NC(=O)Nc2ccc(CC(=O)NC3CC3)cc2)cc1 +C=C(C)COc1ccccc1C(=O)N1CCCC1C(N)=O +Cc1oc(C)c(C(=O)OCc2nccn2Cc2ccccc2)c1C +COc1ccc(-c2cc3[nH]c(C)c(CCC#N)c(=O)n3n2)cc1 +COc1c(F)ccc2c1CCNC2c1cccnc1C +CCS(=O)(=O)c1ccc(NCC(=O)NC)cc1 +N#Cc1cccc(-c2cc(C(=O)c3ccncc3)c(N)o2)c1 +CCCOC(=O)c1cc(-c2cc(Cl)c(O)c(OC)c2)n[nH]1 +CC(C)(CNC(=O)c1cncn1-c1ccccc1)c1ccncc1 +CC(C)(C)c1n[nH]c(C2CN(C(=O)CCCn3cccn3)CCO2)n1 +CS(=O)(=O)c1ccc(-c2noc(-c3ccc(N)cc3)n2)cc1 +O=C(Cc1ccccc1)N1CCC(Oc2cnc3ccccc3n2)CC1 +Cc1cccc(C2NCCc3c(C)cc(F)cc32)n1 +Cc1cc(CNC(=O)Nc2nc(C)c(C)o2)on1 +CNC(=O)NCC(=O)NCCNC(=O)c1ccc(Cl)cc1 +O=c1c(-c2nc(C3CC3)no2)cccn1Cc1c(F)cccc1Cl +CNC(=O)CS(=O)(=O)c1nncn1-c1ccc(C)c(Cl)c1 +O=C(Nc1nc2ccccc2[nH]1)C1CCC(Cn2cnnn2)CC1 +CSc1cc(C(=O)N(C)CC(=O)NC2CC2)ccn1 +Cc1cc(=O)n2c(C)nc(Nc3cccc(C(F)(F)F)c3)nc2n1 +CCCn1c(=O)n(CCC(=O)N(C)c2ccccc2)c2ccccc21 +Cc1ccc2nc3sc(C(=O)N4CCN(C)CC4)cc3cc2c1 +COC(=O)C(c1ccccc1C)N1CCC(c2nc[nH]n2)CC1 +Cc1cccc(C)c1NC(=O)CSc1nnc(-c2ccncc2)o1 +CNC(=O)Cn1ccc2ccc(NC(=O)c3cc(C(C)C)[nH]n3)cc21 +COc1ccc2c(CC(=O)Nc3ccc4oc(C)nc4c3)coc2c1 +CNc1nccc(N2CCC(CC(=O)NCCC(C)C)CC2)n1 +COc1ccc(NC(C)C(=O)Nc2c(C)nn(C)c2C)cn1 +Nc1cncc(S(=O)(=O)NC23CC4CC(CC(C4)C2)C3)c1 +Cc1ccc(OC(C)C(=O)Nc2ccnn2CC(C)C)cc1 +O=C(NCc1ccccn1)c1cc(F)ccc1NC(=O)N1CCCC1 +COC(=O)C(C(C(=O)OC)n1nc(C)cc1C)n1nc(C)cc1C +CC(C)CCNC(=O)c1cc(Cl)ccc1-n1cnnn1 +N#CCCCN1CCOC(c2noc(-c3ccccc3)n2)C1 +COc1cc(C#N)ccc1OC(=O)C(OC)c1ccccc1 +O=C(NC1CC1)C1CCN(c2ccc3nncn3n2)CC1 +O=C(Nc1cccc(Cl)c1)c1nc(-n2cnnc2)ccc1Cl +COc1cccc(-c2csc(NC(=O)c3ccc(C#N)cc3)n2)c1 +Cc1cc(C)c(S(=O)(=O)N2CCN(C)CC2)c(C)c1 +CCN(Cc1ccc(OC)cc1)C(=O)C1CCCO1 +CC(=O)N1CCC(CC(O)Cc2ccnc3ccccc23)CC1 +Cc1ccc(-n2ccc3c(c(C)nc4nc(C)nn43)c2=O)cc1 +CC(CNC(=O)NCC(C)(C)N1CCOCC1)Nc1ccccc1 +N#Cc1ccc(C(=O)NCC(=O)N2CCCC2Cc2ccccc2)cc1 +CCn1c(=O)n(CC(=O)NC(C)c2ccccc2C)c2ccccc21 +CCc1nc(=O)c(C#N)nn1-c1ccc(OC)cc1 +Cc1ccc(-c2noc(CCCC(=O)N3CCCCC3)n2)cc1 +CC(=O)c1cccc(NC(=O)N2CCCC(O)C2)c1 +Cc1ccccc1CC(C)(C)NC(=O)c1ccc2c(c1)NC(=O)CO2 +CSc1cccc(NC(=O)c2ccc3c(c2)nnn3C)c1 +Cc1nc(C)c(C(=O)NC(C)c2ccc(OCC3CC3)c(F)c2)o1 +COc1ccc(C(=O)Cc2nnn(-c3ccccc3)n2)cc1OC +CC(C)c1ccc(OCCc2nc(C(C)N)cc(=O)[nH]2)cc1 +CNC(=O)CNc1ccc(Br)cc1C +Cc1cc(C)cc(CS(=O)(=O)c2nccn2C2CC2)c1 +O=C(COc1ccc(Cl)cc1)NCc1nnc2n1CCCC2 +CS(=O)(=O)NCc1ccc(OC(F)(F)F)cc1 +CCCC1CCC(Nc2ccc3nnnn3n2)CC1 +C=CCNC(=O)c1ccccc1NC(=O)c1cc(C(N)=O)cs1 +CC1CCCCC1OCCNc1ncnc2sccc12 +O=C(NCCc1csc(-c2cccc(F)c2)n1)c1ccco1 +CCS(=O)(=O)N1CCCC(C(=O)Nc2cccc(O)c2)C1 +COCC(=O)NC(C)c1sc(-c2ccccc2F)nc1C +COc1ccc(-c2nnc(CNCC(O)c3ccccc3)o2)cc1 +CNS(=O)(=O)c1cccc(CNC(=O)COC)c1 +O=C(CNc1ccccc1OC(F)F)N1CCCCCC1 +C=C(C)COc1cc(C(=O)NC2CCCC2)ccc1N +Cc1cc(N)cc2c(CC(=O)NCc3ccco3)noc12 +CCCC(=O)Nc1nnc(-c2csc(C)n2)o1 +Cc1nn(CC(C)C)c(C)c1CC(=O)NC(C)Cc1ccccc1F +Cc1noc(COC(=O)c2nn(-c3ccccc3)c3c2CCC3)n1 +CSc1ncccc1C(=O)OCC(=O)c1ccc[nH]1 +Cc1ccc(NC(=O)N2CCN(CC(=O)N3CCCCC3)CC2)cc1 +COc1cccc2cc(C(=O)N(C)c3ccccc3)c(=O)oc12 +Cc1noc2ncc(C(=O)Nc3ccc(Cl)c4ncccc34)cc12 +CC(C)OCCCNc1nc(N)nc2[nH]cnc12 +N#Cc1c(F)cccc1NCCNC(=O)CC1C=CCC1 +CCN(CC)C(=O)NCc1cccc(Br)c1 +Cc1ccc(S(=O)(=O)CC(=O)N(c2ccccc2)C(C)C)cc1 +NS(=O)(=O)Nc1ccc2c(c1)[nH]c1cc(C(F)(F)F)ccc12 +O=C(OCC1CC(=O)N(C2CC2)C1)c1cnc(-c2ccccc2)nc1 +Cc1cccc(NC(=O)CNC(=O)CSc2ccccn2)c1C +Cc1cc(Br)ccc1NCC(=O)N1CCCC1 +O=C(CCc1ccsc1)Nc1cccc(Oc2cnccn2)c1 +COc1ncccc1CN1CC2COCC2(c2nc(C)no2)C1 +O=C(NC1CCN(CC(F)(F)F)C1)c1ccc(O)c(Cl)c1 +O=c1c(NCc2ccco2)nccn1-c1cccc(Cl)c1 +Nc1nonc1C(=O)NCc1cnn2ccccc12 +Cc1cccc(CN2CCN(C(=O)Nc3ccccc3)CC2)c1 +CCOC(=O)c1ccc(-c2ccc(OC)c(OC)c2)[nH]c1=O +COCc1nc(CNc2cccc(-c3ncon3)c2)cs1 +CCC(=O)N1CCc2cc(C(=O)N(C)CCOCC3CC3)ccc21 +Cc1ccc(S(=O)(=O)n2c(C)cc3cccnc32)cc1 +CC(NC(=O)Cc1cccc2ccccc12)C(=O)NC(C)(C)C +CN(CC(O)C1CC1)C(=O)c1ccc(OCc2cscn2)cc1 +Cc1ccc(-n2cnnc2SCC(N)=O)cc1Cl +Cc1ccc(CNS(=O)(=O)N(C)CCC#N)c(N(C)C)c1 +CS(=O)(=O)N(CC(=O)N1CCCC1)c1ccc2c(c1)OCO2 +COc1ccc2c(c1)c1nnc(SC(C)C)nc1n2C +COc1cccc(CNC(=O)c2sccc2C(C)C)c1 +COc1ccc(Cl)cc1N(C)C(=O)C(C)OCC1CC1 +Cc1ccc(C2CC(c3ccccc3F)n3ncnc3N2)cc1 +COc1cc(C)nc2nc(SCc3ccccc3)nn12 +CCc1nn(-c2ccccc2)c(-n2cccc2)c1C#N +CCNC(=O)COC(=O)c1cccc(NC(C)=O)c1 +COCCOC(=O)CN1C(=O)COc2ccc(N)nc21 +CCCn1cnc2cc(CNC(=O)C3CCCC3)ccc21 +CC(CC(=O)N1CCN(CC(O)C(C)(C)C)CC1)C1CC1 +COc1cccc(C(=O)CN2CCNc3ccccc32)c1 +Cc1cc2[nH]c(=O)n(C3OC(CO)C(O)C3O)c2cc1C +COc1cc(OC)c2c(c1)C(c1cc[nH]n1)NCC2 +N#Cc1ccc(OC2CCN(C(=O)c3ccccc3Cl)CC2)nc1 +CCCCCN1CC(C(=O)Nc2ccc(C)cc2)CC1=O +CCS(=O)(=O)N1CCC(NC(=O)NCCc2cccs2)CC1 +Cc1nc(C)c(CNC(=O)NCc2cccc(-n3cncn3)c2)s1 +C=CCN(Cc1cnc2c(C)cccn12)CC(F)(F)F +COc1ccc(NC(=O)c2cc(C(C)C)on2)cc1OC +O=C(Nc1ccccc1F)C1CC(=O)N(c2cccc3ccccc23)C1 +Cc1[nH]c2ccccc2c1C(=O)OC(C)C(=O)N(C(C)C)C(C)C +CCCN(Cc1ccc(C)cc1)C(=O)CSc1nncn1C +CCc1ccc(CN2CCOC(C(=O)OC)C2)o1 +Cn1ccc(C(=O)NCc2ccn(-c3ccc(F)cc3)n2)cc1=O +CCN(CC(F)(F)F)C(=O)c1nc2nc(C)cc(C)n2n1 +CC(=O)c1ccc(C(=O)N2CCOC(Cc3ccccc3)C2)s1 +COCCOc1ccc(F)cc1NC(=O)C1CC2CCC1O2 +CC(C)NC(=O)CCNC(=O)NCCc1c(Cl)cccc1Cl +CCOC(=O)c1c(-n2cnnn2)sc(C)c1C +Cc1noc(NC(=O)CSc2ccc3c(c2)CCC3)n1 +Cn1cc(N2CCC3(CCN(C(=O)c4cccs4)C3)C2=O)cn1 +CCS(=O)(=O)c1nccn1-c1cccc(F)c1 +CSc1ccccc1NC(=O)N1CCOC(C)C1 +C#CCNC(=O)CNC(=O)Nc1cc(C)ccc1S(C)(=O)=O +Cc1cc(NC(=O)C(C)Oc2ccc(F)cc2F)no1 +COc1ccc2c(c1)CC(NS(=O)(=O)c1c(C)noc1C)CO2 +Cc1noc(CNC(=O)c2cccnc2N(C)C)n1 +CCOC(=O)C(N)Cc1cc(-c2cc[nH]n2)ccc1F +CC1(C)OCC2(CO1)CN(C(=O)c1cc(-c3ccccc3)on1)C2 +CC(C)n1nnnc1COc1ccc(C(=O)Nc2nccs2)cc1 +Cc1sc(C(N)c2ccccc2)nc1-c1ccccc1 +CC(=O)Nc1nc2ccc(C(=O)NC(CO)CC(C)C)cc2s1 +O=C(CC1CCCCC1)NCCNC(=O)c1scnc1C1CC1 +CCCC(=O)N1CCN(c2ccccc2Cl)CC1 +CC(C)N(C)C(=O)c1csc(Cc2ccccc2)n1 +Cc1nc(CCNC(=O)c2cccc(OCC3CCCO3)c2)cs1 +CC(C)S(=O)(=O)N1CCN(c2ccc(-n3ccnc3)nn2)CC1 +OCCCn1nncc1-c1ccc(Cl)c(Cl)c1 +N#Cc1oc2ccccc2c1NC(=O)COC(=O)CCc1ccccc1 +CCC(=O)N1CCc2c(C(=O)Nc3ccc(OC)cc3)cccc21 +Cn1nc(C2NCCc3ccc(F)cc32)c2ccccc21 +COCc1cccc(CNC(=O)Nc2ccncc2F)c1 +COC(=O)c1ccnc(N2CCCN(C(=O)c3cnccn3)CC2)c1 +CCc1ccc(C(=O)Nc2cccc(S(=O)(=O)N(C)C)c2)cc1 +COCCOc1cccc(C(=O)N2CCNC(=O)C2)c1 +CNC(=O)C1CCN(c2ncnc3ccccc23)CC1 +CCC1c2ccsc2CCN1S(=O)(=O)c1ccc(C#N)cc1 +COC(=O)c1ccccc1NC(=O)c1cncc(Br)c1 +COc1cccc(N2CCN(C(=O)c3ccc(C)c(F)c3)CC2)c1 +CCS(=O)(=O)N1CCc2ccc(Cl)cc2C1 +CC(NC(=O)c1ccco1)C(=O)NCc1ccnc(OC2CCC2)c1 +CCC1=C(C(=O)OC)C(c2ccccc2F)n2nnnc2N1 +CCC(C)(C#N)NC(=O)C1CCOc2ccccc21 +COc1ccccc1C(=O)OCC(=O)Nc1ccccc1 +Cc1ncsc1C(=O)NCc1ccc(-n2cnc3ccccc32)nc1 +CC(=O)OC1CCCN(C(=O)OC(C)(C)C)C1OC(C)=O +COCCNC(=O)CCc1c(C)nn(-c2nc(C)c(C)c(=O)[nH]2)c1C +COc1ccccc1OCCN(C)C(=O)Cc1ccc(F)c(F)c1 +Cc1nnc(C)c2c(C)n(NC(=O)c3ccncc3)c(C)c12 +CCN(CC)C(=O)c1ccccc1SCc1c(C)noc1C +Nc1ccc(F)c(C(=O)Nc2ccc(Cl)cc2)c1 +CC(C)(C)CC1CCCN1C(=O)c1cccc(-n2cccn2)n1 +Cc1ccc(C(=O)OCC(=O)NC2CCCC2)cc1 +CN1CC(c2n[nH]c(=O)n2CCc2ccccc2F)CC1=O +OC1c2ccccc2C(O)c2cc(Br)ccc21 +CC(C)(C)CCNC(=O)c1c(O)cc(F)cc1F +Cc1ccc(-c2ccc(C#N)c(=O)n2CC#N)cc1C +CCn1c(CNC(=O)c2ccc(Cl)cc2)nc2ccccc21 +COCCCC(=O)N1CCC(c2nnc3ccccn23)CC1 +CC1(C(=O)N2CCN(Cc3ccc(F)cc3)C(=O)C2)CCCO1 +COc1cc(C)c(NC(=O)N2CC(C)OC(C)C2)cc1OC +O=C(NCc1ccc2c(c1)OCO2)Nc1ccc(F)c(Cl)c1 +c1cc(CN2CCOCC23CCC3)cc(-n2cccn2)c1 +Nc1nccnc1C(=O)NCc1ccc(CS(N)(=O)=O)cc1 +CC(=O)N(C)CC(=O)Nc1cc(Cl)c(C)cc1Br +CC(NC(=O)Nc1cnn(CC2CCCO2)c1)c1ccc(Cl)cc1 +CC(C)N(CCCO)c1ccc(S(C)(=O)=O)cc1N +O=C(NC1c2ccccc2-c2ccccc21)c1ccco1 +COCC(=O)N1CCN(c2ccc(N3CCCCC3C)nn2)CC1 +CN(Cc1cc2ccccc2o1)C(=O)NCCNC(=O)C1CCCC1 +CCc1nc2n(n1)CCCC2NC(=O)c1cc(Br)c[nH]1 +O=C(CCc1cccnc1)Nc1ccc2c(c1)OCC(=O)N2 +CCC(NCC(F)(F)F)c1ccc(Cl)cc1 +COc1ccc(CNc2cnn(C(C)C)c2)c(OC(C)C)c1 +CC=CCS(=O)c1nncn1-c1ccccc1OC +CN(CC(=O)Nc1ccc(C#N)cc1)C(=O)c1cccs1 +O=C(NCCc1nc2ccccc2[nH]1)Nc1ccccc1 +CC1C(=O)Nc2ccc(C(O)Cc3cccs3)cc21 +O=S(=O)(NC1CCCc2ccccc21)c1cccs1 +O=C(NCc1ccccc1)c1cnn2ncccc12 +CC(C)CCC(=O)NC1CCc2nnc(C(C)C)n2C1 +CNC(=O)c1cccc(OCc2ccc(C(=O)OC)c(F)c2)c1 +CN(CCc1ccccn1)S(=O)(=O)c1ccc(C(F)(F)F)nc1 +Cc1cc(NC(=O)NCC2(C)CCCO2)c2ncccc2c1 +CCC(=O)Nc1nnc(CCOc2ccc(C)c(C)c2)s1 +O=C(NC1CCc2ccccc21)N1CCOC(c2cccc(O)c2)C1 +CCCOc1ccc(C(=O)N2CCC(C(N)=O)CC2)cc1OCC +Cc1noc(C2CCCCN2C(=O)c2ccncc2)n1 +CCCCNC(=O)C1CCN(c2cc(N3CCCCC3)ncn2)CC1 +Cc1nc(CCn2ccnc2-c2ccc(-c3cc[nH]n3)o2)sc1C +O=C(c1ccc(Cl)cc1O)N1CCCCC1CCO +Cc1nnc2ccc(N3CCCC(C(=O)NC4CCCC4)C3)nn12 +Cc1nc(O)cc(C2CN(C(=O)C3CC3)CC2c2ccccc2F)n1 +CNC(=O)Cc1ccc(NC(=O)NCc2ccc(OC)cc2)cc1 +Cc1ccc(-c2ccc3nc(C)[nH]c(=O)c3c2)cc1 +CC(C)c1c(C(=O)NCC2CC2)cnn1-c1ccccc1 +Cc1noc(C)c1S(=O)(=O)NCc1ccnn1C +COc1cccc(C(NC(=O)N2CCCC(C)C2)c2nccn2C)c1 +C=CCN(c1cc(CC)nc(-c2ccccn2)n1)C1CC1 +Cc1ccc(-n2ncc(C(=O)Nc3nncs3)c2C(C)C)cc1 +Cc1[nH]ncc1C(=O)N1CCN(CC(O)C(C)(C)C)CC1 +CN1CC2(CCN(C(=O)c3[nH]cnc3-c3ccccc3)C2)OC1=O +COCCOCCC(=O)NC1CCOc2c(Cl)cccc21 +CC(O)CN1CCN(C(C)C(=O)NCCC2=CCCCC2)CC1 +O=C(CCC(=O)N1CCc2ccccc21)Nc1nccs1 +Cc1ccc(C(=O)Nc2cc(-c3ccn[nH]3)c(C)n(N)c2=O)cc1 +N#Cc1cccc(S(=O)(=O)NCC2CCC2)c1 +O=C(NCC(=O)N1CCCCC1)c1ccc(F)cc1F +CC(C)(C)c1noc(CCC(=O)NCC2CCC2)n1 +CC(C)=C1C(=O)N(C)c2ccc(S(=O)(=O)NC(C)C)cc21 +CC(C)(C)c1ccc(Oc2nnnn2-c2ccc(C(N)=O)cc2)cc1 +OCc1nnn(Cc2ccccc2F)c1-c1ccccc1F +C=CCNS(=O)(=O)c1ccc(Cl)c(C(F)(F)F)c1 +CCOCC(=O)Nc1ccc(-n2cnc3ccccc32)nc1 +c1csc(-c2nnc(NCc3cccc4c3OCO4)o2)c1 +Cc1ccc(CCN2Cc3nc(N4CCCC4)ncc3C2=O)cc1 +CCOC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)CC +CC(C)CC(O)C1CCN(c2nccnc2N(C)C)CC1 +CC(C)COc1ccccc1CNc1ccc(C(=O)N(C)C)cn1 +COc1cccc(C(N)=O)c1OCc1csc(C)n1 +Cc1ccc(C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)c(C)n1 +CCCNC(=O)CN1CCN(C(=O)C2CCCCC2)CC1 +CC(=O)N1CCc2cc(NCc3cccc4c3OCCCO4)ccc21 +Cc1ccn(-c2ccc(Cl)c(Cl)c2)c(=O)c1C#N +CSc1ccc(C(=O)Nc2cccc(C)c2C(N)=O)cc1 +Cc1ccsc1CNC(=O)CN(C)Cc1nc2ccccc2s1 +CCc1nnc2n1CCN(C(=O)COCc1cccc(OC)c1)C2 +O=C1NCC(=O)N2CCN(c3ccc4cc[nH]c4n3)CC12 +C#Cc1cccc(N(C(=O)COc2ccccc2)C(C)C)c1 +COCC(=O)Nc1ccc(NC(=O)NCc2ccc(Cl)cc2)cc1 +CC(C)COCCCNC(=O)NC1CCc2cc(F)ccc21 +CCNC(=O)c1ccc(NC(=O)c2cccnc2-n2cccn2)c(C)c1 +Cc1cc2ccccc2n1CCC(=O)N(C)Cc1ccco1 +CC1CCCC(NC(=O)c2ccc(CNC(N)=O)cc2)C1 +CCOC(=O)CN(CC)C(=O)c1c(C)nc(C)nc1SC +CC(C)c1nc(CCNC(=O)Cc2cccc(F)c2F)cs1 +CN1C(=O)Cc2cc(NS(=O)(=O)Cc3ccccc3F)ccc21 +COC(=O)C(NS(=O)(=O)c1c(C)sc2ccccc12)C(C)C +Cn1cnc(CNC(=O)c2ccccc2Oc2cccnc2)n1 +O=C(COc1ccc(-n2cccn2)nn1)Nc1ccc2c(c1)OCO2 +CC(=O)N1CCNC(=O)C1c1ccc(C(F)(F)F)cc1 +Nc1nc(C2CCCCC2)ncc1C(=O)NC1CC1 +COC(=O)C1CC(O)CN1Cc1cccc(C)c1C +CC(=O)c1c(C)[nH]c(C(=O)Cn2nnn(-c3cccs3)c2=O)c1C +O=C(NCC1CN2CCCCC2CO1)C1CC1c1cccc(Cl)c1 +Cc1cc(OCC(=O)N(C)Cc2nc3ccccc3s2)no1 +NC(=O)c1cccc(NC(=O)c2cc(C3CC3)nn2-c2ccccc2)c1 +COC(=O)NCC(=O)Nc1cc(C(C)(C)C)n[nH]1 +CCN1CC2(CCCN(C(=O)Cc3ccccc3O)C2)CCC1=O +CC(C)(C)CC(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CC(=O)Nc1ccc(NC(=O)CN(C)C(C)=O)cc1 +COC(=O)c1ccc(C(C)N2CCOC(c3ccc(C)o3)C2)o1 +CNC(=O)CNC(C)c1c(Cl)ccc(F)c1Cl +O=C(OCC(=O)N1CCOCC1)c1cccnc1N1CCOCC1 +COC(=O)CCN(C)C(=O)c1cc2ccccc2o1 +COCCNc1nnc(Cn2nnc3ccccc32)s1 +Cc1cc(C2CCCN2C(=O)c2c(Cl)cnn2C)no1 +CC1CCCCC1OCCNC(=O)Cn1nnc(-c2cccs2)n1 +CSc1nnc2nc3c(nn12)c1ccccc1n3C +Cc1cccc(NCC(=O)N(C)Cc2cccs2)c1 +O=C(NCCOc1ccc2c(c1)OCO2)c1cncc2cnccc12 +Cc1cc(O)c2c(C)c(CC(=O)Nc3cccnc3)c(=O)oc2c1 +O=C(Cn1cnc2ccccc21)NCCC1=CCCCC1 +COC(=O)c1ccc(C(=O)NCc2nc3ccccc3s2)cc1 +COC(C)C(=O)Nc1ccccc1NC(=O)NC(C)C +COc1ccc2nc(SCC3=NC4C=CC(C)=CN4C3)[nH]c2c1 +CCOc1ccc(-c2cc3[nH]c(C(C)N)cc(=O)n3n2)cc1 +Nc1ccc2oc(CC(=O)Nc3ccccc3Cl)nc2c1 +O=S(=O)(Cc1noc(C2CC2)n1)c1ccc(Br)cc1 +O=C(NC1CCCc2ccccc21)c1cccc(F)c1 +Cc1ccc(-c2nnc(SCCCN3CCOC3=O)o2)cc1C +COc1ccc(-n2ccnc2C(C)(C)CN2CCOCC2)cn1 +COC(=O)c1cc(C2CC(=O)Nc3n[nH]cc32)ccc1O +Cc1noc(C)c1CC(=O)NCC1(c2ccc(F)cc2)CCC1 +COc1ccc(C(=O)Nc2nccn(C)c2=O)c(OC)c1 +O=C(Cc1ccc(O)cc1)N1CCN(Cc2ccc(Cl)cc2)CC1 +CCOC(=O)C(C)(COC)Nc1cccc(C)c1 +Cc1nnc2ccc(NCC(c3cccs3)N(C)C)nn12 +NC(=O)C1CCCN(C(=O)CNc2cc(F)cc(F)c2)C1 +NC(=O)CSc1ccccc1NC(=O)CCc1ccccc1F +Cc1cc(Br)c2onc(CCO)c2c1 +CCc1nc(C)c(C(C)OC(=O)c2ccc(CNC(N)=O)cc2)s1 +CCOc1cccc(Cn2cnc3c(nnn3-c3ccccc3)c2=O)n1 +CC1(C)CN(C(=O)Nc2ccc(Cn3cccn3)cc2)CCO1 +CC(C)CCC(=O)N(C)C(C)c1ccc(-n2cncn2)cc1 +CC(C)S(=O)(=O)N1CCC(c2cc(N)on2)CC1 +CCCNC(=O)Nc1ccc(S(=O)(=O)N(CC)CC)cc1 +Cc1nc2c(C(=O)C3CC3)cccc2n1-c1ccccc1 +CCc1cc2c(N3CCCCC3CCO)ncnc2s1 +COC(=O)N1CCC(CNC(=O)c2c(OC)cccc2OC)CC1 +CCCOC(=O)C(C)n1cc(CO)c2cc(C)ccc21 +Cc1ccc(NC(=O)CCc2c(C)nc3c(c(C)nn3C)c2C)nc1 +Cc1nn(CC(C)C)c2c1C(c1cnn3cccnc13)CC(=O)N2 +O=C(NC=Cc1ccco1)NCc1ccc(Cl)cc1 +Cc1cccc(C(=O)Nc2noc3nc(C)cc(C)c23)c1 +CCNc1ncc(C(=O)NCc2csc(-c3ncccn3)n2)cn1 +Cc1cc(-n2cncn2)ccc1C(=O)Nc1cccnc1N1CCCC1 +COc1ccc(CNC(=O)N2CC(c3nc(C)no3)C2)cc1OC +Cc1csc2nc(CN3CCOCC3C)cc(=O)n12 +Cc1noc(CNC(=O)NC(C)c2ccccc2Br)n1 +CCCC(C)NC(=O)N1CCN(c2cnccn2)CC1 +CCCn1cc(Cl)cc1C(=O)N(C)CC(O)COC +Cn1ccc(S(=O)(=O)NCCNc2nc3ccccn3c2C#N)c1 +CCCN(C)c1ccc(C(=O)Nc2ccccc2-n2cnnn2)cc1 +CCN(CC(C)C#N)C(=O)c1ccccc1-c1ccccc1C#N +Cc1ccc(Nc2nc(=O)[nH]c3c2cnn3C)c(C)c1 +FC(F)(F)c1ccc2nnc(-c3cccnc3)n2c1 +NC(=O)c1ccc(NC(=O)c2csc(Nc3ccccn3)n2)cc1 +O=C(COC(=O)c1cc(-c2ccccc2)[nH]n1)NCc1cccs1 +O=C1CCCCN1c1cccc(NS(=O)(=O)c2ccccc2F)c1 +COC(=O)c1ccc(S(=O)(=O)Nc2ccc(C)cc2)cc1 +NC(=O)C1CCN(C(=O)NCc2ccccc2-n2cccn2)CC1 +CCC(c1cccs1)n1cc(Cn2c(=O)oc3ccccc32)nn1 +CCC(C)N(C)C(=O)NCC(=O)N(CC)Cc1ccccc1 +Cc1nc2ccccc2n1CCNC(=O)c1ccc2nncn2c1 +Cc1nnc(NCCn2c(C)nc3ccccc32)c(C#N)c1C +COC(=O)CCNC(=O)c1csc(-c2cccs2)n1 +CC(Nc1ncccc1C#N)c1ccccc1C(F)(F)F +Cn1cnc2cc(-c3cn(-c4cccc(N)c4)nn3)ccc21 +CN(C(=O)c1ccc2nccn2c1)C1CCCN(c2ccccc2)C1 +CC(C(=O)N1CCCC1)N1CCSc2ccc(N)cc21 +CCCCn1nc(C(=O)NC(CC)CO)ccc1=O +COc1cccc(N2CCN(Cc3cc(=O)c(OC)c[nH]3)CC2)c1 +Cc1ccc(CNC(=O)c2nn(-c3ccccc3F)nc2CO)cc1 +CCc1cc(=O)[nH]c(SCC(=O)NC2CCCC2)n1 +COc1ccc(NC(C)=O)cc1NC(=O)CCC1CCCCC1 +CCNC(=O)c1ccc(NCc2ccc[nH]2)c(C)c1 +O=S(=O)(c1cccs1)N(Cc1cccnc1)C1CC1 +COC(=O)C(C)(C)NC(=O)c1cccnc1OC +O=C(c1cccc(Cl)c1)N1CC(c2nc(-c3cccnc3)no2)C1 +CC(=Cc1ccccc1)CN1CCNC(C(=O)N2CCOCC2)C1 +Cc1cc(C(=O)Nc2ccc(Cn3cncn3)cc2)c2c(C)noc2n1 +CCc1cc(C(N)=O)c(NC(=O)C2CCCCC2)s1 +O=C(NCc1nnc(-c2nccc3ccccc23)o1)C1CC1 +Cc1ncc(Cl)c(C(=O)N(C)CC2CCCO2)n1 +COC(=O)c1c(C)ccc(F)c1NC(=O)c1cncc(F)c1 +Cc1cc(N(C)C)nc(C2CCCN2S(C)(=O)=O)n1 +COc1cc(OC)c(NC(=O)NCC2Cc3ccccc3O2)cc1F +COCC(=O)NC1CC(=O)N(CCc2ccc(OC)cc2)C1 +Cc1cccc(N2CCN(C(C)C(=O)c3ccc(N)cc3)CC2)c1 +CNC(=O)C1CCN(C(=O)c2c(C)nn(-c3ccccc3)c2C)CC1 +CCN(Cc1ccccc1Cl)C(=O)c1cccc(N(C)C)c1 +COc1ncc(C2NCCc3c(F)cccc32)c(OC)n1 +N#Cc1nnn(Cc2cccc3ccccc23)c1-c1ccco1 +CCOCCNC(=O)N1CCC(NC(=O)c2ccccc2C)CC1 +CC(=O)N1CCN(C(=O)CN2CCN(CC(F)F)CC2)CC1 +C=CCNC(=O)NC1CCN(S(=O)(=O)CCC)CC1 +CC(C)n1nccc1-c1nnc(NC(=O)COc2ccccc2F)o1 +CNC(=O)COC(=O)c1ccn(-c2ccccc2Cl)n1 +CN(CC(N)=O)S(=O)(=O)c1ccc(F)c(Cl)c1 +Cn1ncc(C(=O)OCC(=O)N2CCCCCC2)c1-n1cccc1 +Cc1nc(C(=O)NC2(CO)CCCC2)ccc1C#N +COC1CCCN(C(=O)c2ccc(C)c(NC(=O)c3ccco3)c2)C1 +O=C1CSc2ccc(C(=O)N3CCOC4CCCCC43)cc2N1 +O=C(CN1C(=O)CCSc2ccccc21)Nc1ccc(Cl)cc1 +CC1CCCN(S(=O)(=O)c2ccc(F)cc2Br)C1 +CCOC(=O)c1c(-n2cnnn2)sc2c1CCC(C)C2 +Cc1cc(C(=O)NC(CO)c2ccccc2)c2cnn(C)c2n1 +CCC(C)(C)NC(=O)CNC(=O)OCc1ccccc1 +CCCc1noc(COc2ccc(C(=O)CC)cc2)n1 +CN(Cc1ccsc1)C(=O)c1scnc1C1CC1 +CCCCN(CC)C(=O)NC1CCC2(CC1)OCCO2 +Nc1cccc(NC(=O)c2ccc3ccccc3n2)c1 +CCC(Sc1cc(C)ncn1)C(=O)Nc1c(C)cccc1C +O=C(Nc1ccc2[nH]ncc2c1)c1n[nH]c2cccc(Cl)c12 +Cc1ccc(C(=O)Nc2ccc(NS(C)(=O)=O)c(Cl)c2)s1 +CCCc1nnc(SC(C)c2nc3sc(C)c(C)c3c(=O)[nH]2)[nH]1 +c1cc2ccc(-c3noc(CCN4CCOCC4)n3)cc2[nH]1 +CN1CCN(C(=O)c2ccnc(-c3ccc(-c4ccn[nH]4)cc3)c2)CC1 +O=C(Cc1ccc(O)cc1)NC(c1ccccc1)C1CC1 +Cc1nc(C)c(C(=O)Nc2cc(C#N)ccc2C)s1 +Nc1ncnc2c1ncn2CCCSc1ccnc2ccccc12 +CCc1ccc(-n2nc(CO)c(C(=O)NC)n2)cc1 +O=C(c1ccc2[nH]c(C(F)(F)F)nc2c1)N1CCCCCC1 +CS(=O)(=O)c1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)cn1 +CC(Sc1ccccc1)C(=O)Nc1ccccc1-n1cnnn1 +Cc1ccc(C)c(NC(=O)CC(C)C2COCCO2)c1 +CCOCc1cccc(NC(=O)C2(c3ccccc3)CCOCC2)c1 +Cc1ccc2nc(CSc3nnnn3-c3ccc(O)cc3)cn2c1 +CNS(=O)(=O)C1CCCN(C(=O)Nc2ccc(C)c(Cl)c2)C1 +Cc1cc(Br)ccc1OCC(=O)Nc1cccnc1 +CCOCC(=O)N1CCN(c2ccc(C#N)cc2)C(=O)C1 +COc1cc(OC)c(NC(=O)CSc2cn[nH]n2)cc1Cl +COC(=O)c1ccc(CNC(=O)c2ccc(OC)c(F)c2)cc1 +COc1cccc(OCCc2nnc(NC(=O)C(C)C)s2)c1 +CN(Cc1ccsc1)C(=O)COC(=O)c1n[nH]c2ccccc12 +Cc1cccc(NC(=O)Cc2cn3ccccc3n2)c1C +Cn1nnnc1SCC(=O)c1ccccc1Br +CC(C)C(=O)Nc1ccc(C(=O)N(C)C)c(Cl)c1 +O=C(NCCn1cccc1)c1occc1CN1C(=O)Cc2ccccc21 +CC(C)Cc1noc(COc2cc(Cl)ccc2C(N)=O)n1 +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)c1ccc(F)c(F)c1 +COc1ccc(NC(=O)C2CC(=O)Nc3cc(F)ccc32)cc1Cl +CCOCC(=O)Nc1cc(-c2ccccc2)ns1 +N#CCCN(Cc1cccnc1)Cc1ccccc1C(F)(F)F +CCC1COCCN1CCCC(=O)c1ccccc1 +CCOC(=O)C1CCN(C(=O)c2cnn(C)c2)CC1 +COCCN(Cc1nnc(-c2cccs2)o1)C(=O)c1cc(C)on1 +COC(=O)c1cc2sc(C)cc2n1CC(=O)N(C)c1ccccc1 +CC(C)NC(=O)Nc1ccccc1-n1cc(Br)cn1 +Cc1noc(C)c1CCC(=O)NCCc1ccc2c(c1)OCCO2 +Cc1cc(NC(=O)NCC(=O)N2CCCCC2)c2ncccc2c1 +N#CC(c1cccc(Cl)c1)N1CCC(O)CC1 +Cn1nncc1CN1CCN(C(=O)C2CCCCC2)CC1 +CC(C)Cc1nnc2c(N)cc(Br)cn12 +Cc1nc2nc(C)c3c(=O)n(CCCO)ccc3n2n1 +CCCc1[nH]nc(C(=O)NC2CCOCC2)c1N +C=CCn1c(SCc2nc(C3CC3)no2)nnc1-c1ccco1 +Cc1ccc2c(c1)NC(C)(C(C)C)CN2CCC#N +N#Cc1c(N)nc2c(c1-c1ccncc1)CCc1c(O)cccc1-2 +NC(=O)CC1CCN(c2cc(N)cc(F)c2)CC1 +CCCC(C)C(=O)Nc1cccc(-c2cn[nH]c2)c1 +CCc1nc2nnc(-c3ccnc(Nc4cccc(C)c4)n3)c(C)n2n1 +CN(C)c1nc(CN(C)S(=O)(=O)c2cccs2)ns1 +O=C(CSc1nncn1C1CC1)NCCCO +COc1ccc2c(c1)nc(C#N)n2Cc1ccccc1C#N +O=C(CCc1cccs1)N1CCC(N2CCNC2=O)CC1 +COc1ncnc2c1CCN(C(=O)c1ccsc1)C2 +O=C(CCSc1nnc(-c2ccco2)o1)Nc1ccccc1 +CC1CC(=O)c2cc(C(=O)Nc3ccc4c(c3)OCO4)c(=O)[nH]c2C1 +O=C(NC1C2CC3CC(C2)CC1C3)C1COCCO1 +CN(C)C(=O)C(OC(=O)c1ccccc1O)c1ccccc1 +Cc1cccc(NC(=O)Cn2ncc3ccccc3c2=O)c1C(N)=O +O=C(CNc1cccc(C(=O)N2CCCCC2)c1)NCC1CCCO1 +CCOC(=O)c1cnc(SC)n1-c1ccccc1 +CN(C)C(=O)c1ccc(C(=O)Nc2nc(C3CC3)cs2)cc1 +CCOc1ccc(S(=O)(=O)N2CCN(C(C)=O)CC2)cc1 +O=S(=O)(NCCCn1ccc2ccccc21)c1cccs1 +CNC(=O)NCC(=O)NC(c1ccccc1OC)C(C)(C)C +COCCNC(=O)c1nc(-c2ccc(C)cc2)n2c1CCCCC2 +COc1ccc(S(=O)(=O)Nc2cc(C(C)(C)C)on2)cc1OC +Cc1ccoc1C(=O)N(C)C(C)c1ccc(S(N)(=O)=O)cc1 +Cc1ccc(S(=O)(=O)NCC2CCCO2)cc1C(=O)NC(C)C +CC(=O)c1ccc(NC(=O)Cn2ccc(=O)c3ccccc32)cc1C +COc1cc(OC)c(-c2nnc(CCO)o2)c(OC)c1 +O=C(COC(=O)Cc1ccc(F)c(F)c1)NC1CCCCC1 +COC(=O)Cn1c(=O)ccc2cccc(OCc3ccccc3)c21 +CC1Oc2ccc(-c3cc(CO)n[nH]3)cc2N(C)C1=O +C=CCNC(=O)C1CCN(S(C)(=O)=O)c2ccccc2O1 +COc1ccc(C(C)NC(=O)CCc2nc3ccccc3[nH]2)cc1F +CC(=O)Nc1cc(NC(=O)CSc2nccn2C)ccc1C +COc1cccc(OC)c1C(=O)NCc1cccc(O)c1 +Cn1c(=O)cc(C(=O)Nc2cnc3n2CCCC3)c2ccccc21 +Cc1nn(CC(=O)N2CCN(C)CC2)c(=O)c2cc3sccc3n12 +CCOc1ccc(CNC(=O)c2ccc(-n3ccnn3)cc2)cc1F +CCc1ncc2c(n1)CN(C(=O)c1cccc3cc(C)oc13)C2 +CCc1ccc2c(CC(=O)NC3CCOc4ccccc43)coc2c1 +O=C1Cc2cc(NC(=O)c3ccc4cc[nH]c4c3)ccc2N1 +CC(=O)NC(CC(=O)NCCC1=CCCCC1)c1ccccc1 +Cc1cccc(NC(=O)Cc2c(C)nn(-c3ccccc3)c2C)n1 +Cn1cc(C(=O)OCc2nc(-c3cccnc3)no2)c(C(C)(C)C)n1 +CCc1cccc(CC)c1NC(=O)Cn1nnc(-c2ccccc2)n1 +CC1CCc2nn(CC(=O)NCCCc3ccccc3)cc2C1 +COc1cc(CN(C)c2ncccc2C#N)ccc1OC(F)F +COCCNC(=O)CC1CCN(C(=O)Nc2ccc(C)cc2)CC1 +Cc1n[nH]c(C2CN(C(=O)CCCNc3ncccn3)CCO2)n1 +C#CCNC(=O)C(NC(=O)OC(C)(C)C)C(C)C +Cc1cccc(-n2ncc(C#N)c2C(F)(F)F)c1 +CCOC(=O)N1CCN(c2nnc(SCC(N)=O)s2)CC1 +NC(=O)c1ccc(NCC(=O)NC2CC2)cc1Cl +C#CCOc1cccc(NC(=O)c2cc(C)n(-c3ccccc3)n2)c1 +COCc1cccc(NC(=O)NC(c2ccccc2)c2ccncc2)c1 +CCCNC(=O)CCC(O)c1ccc(Cl)cc1 +COCCCn1ccc(NC(=O)NC2CC2C)n1 +Cc1cccc(OCCN2C(=O)C(C(C)C)Oc3ccc(N)cc32)c1 +Cc1ccc2[nH]c(=O)c(CN(C)C(=O)c3ccccc3C)cc2c1 +Cc1nc(SCC(=O)NCc2cc(F)cc(F)c2)oc1C +COCc1cc(C)nc2sc(C(=O)OC)c(-n3cccc3)c12 +CCN(CC(C)C#N)C(=O)c1cc(C)nc2c1cnn2C(C)C +CC(C)(O)c1cnc(CCN2CCOCC2)s1 +CC(=O)NC1CCCN(C(=O)NC(C)Cc2ccco2)C1 +CCc1ccc(-n2nc(CO)c(C(=O)NCc3ccccn3)n2)cc1 +Cc1ccc(-c2noc(CCn3cncn3)n2)cc1F +COCC(=O)NCc1ccc(C(=O)NC2CC2)cc1 +CC(C)CNC(=O)N1CCCC(CC(=O)Nc2cccnc2)C1 +Cc1cccc(C)c1CSc1nc(N)cc(N)n1 +COCCNCc1nc(=O)c2cc(-c3ccccc3)sc2[nH]1 +Cc1nn2c(CCOc3ccccc3N)nnc2s1 +c1ccc(-c2nc(CSc3nnnn3C3CC3)cs2)cc1 +Cc1ccc(-c2nnc(CN(C)C(=O)c3ccco3)o2)cc1 +Cc1nnc(-c2cnn(C)c2N)n1Cc1ccncc1 +Cc1ccc(C2COCCN2Cc2cnc3ccsc3c2)o1 +CC(C)OCc1cccc(NC(=O)c2cn3cccnc3n2)c1 +CCn1nnnc1SCC(=O)N1CCN(c2ccccc2)CC1 +COC(=O)CN(c1ccc2c3c(cccc13)CC2)S(C)(=O)=O +Cc1cc(O)ccc1NC(=O)Cc1ccc(Cl)cc1 +CC(C)(C)C(=O)N1CCC(C(=O)Nc2cc(F)c(F)c(F)c2)CC1 +O=C(OC1CCOC1=O)c1ccc(Oc2ccc(F)cc2)cc1 +CNC(=O)CCc1ccccc1NC(=O)N1CCCC1CO +COC(=O)CCC(=O)Nc1cccc(Cl)c1N1CCOCC1 +CCCc1nnc(NCc2ccc(OC)c(O)c2)o1 +Cc1nc(C)c(CNC(=O)N2CCc3ccc(Cl)cc3C2)s1 +OC(CNc1nc(-c2cccnc2)nc2ccccc12)c1ccccc1 +Cc1nn(-c2ncccn2)c2c1C(c1ccsc1)CC(O)=N2 +COC(=O)CCCC(=O)N1CCC(=Cc2ccccc2)CC1 +COc1ccc(CNC(=O)Nc2cc(Cl)ccc2C)cn1 +Cc1noc(C)c1N(C)CCOc1ccccc1Br +CS(=O)(=O)NC1CCCN(C(=O)NCc2cccc(C#N)c2)C1 +O=C(c1ccc(O)cc1)N1CCN(C(=O)C2CCOCC2)CC1 +Cn1cc(CNC(=O)N2CCCC2Cc2ccccc2Cl)cn1 +CN(CCS(=O)(=O)c1ccccc1)CC1COc2ccccc2O1 +Cc1cc(C(=O)Nc2cc(C)nn2-c2ccccc2)n(C)n1 +Cc1nn(C)c2c(N3CCCCC3)nc(C(C)C)nc12 +CCN(Cc1ccccc1NCc1nc(C)cs1)C(C)=O +Cc1ccc(C(=O)NCC(=O)Nc2cccc(C(=O)N(C)C)c2)s1 +COc1c(Cl)c2c(c(OC)c1OC)C(C)NCC2 +CCCN(C)C(=O)c1ccc(C(=O)NC(C)(C)C)cc1 +Cn1ncc2c(Nc3cccc4c3CCCC4)ncnc21 +N#Cc1nc(N2CCC(C(=O)N3CCCCC3)CC2)ccc1Cl +Cc1[nH]ncc1CCCNC(=O)Nc1ccncc1 +O=C(NCc1cc2c(s1)CCC2)c1cc2ccccc2c(=O)[nH]1 +CNc1ccc(S(=O)(=O)NC2CCCCC2O)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)CNC(=O)c1cccs1 +CC(OCC1CC1)C(=O)Nc1ccccc1Sc1nncs1 +COCC(NC(=O)CC1CCCCC1(C)C)C(N)=O +Oc1cccc(CNc2ccc(OCC(F)(F)F)nc2)c1 +CCOC(=O)C1(O)CCN(C(=O)c2ccccc2C)CC1 +Cn1ncc(Cl)c1-c1nnc2sc(Cc3ccc(F)cc3)nn12 +O=C(NCC1(O)CCc2ccccc2C1)c1cccs1 +CC(Oc1ccccc1)C(=O)Nc1cc(-c2ccccn2)no1 +Cc1ccc(N2CCCC2)c(C(=O)N2CCCC(c3ccn[nH]3)C2)c1 +CC1COCC(C)N1C(=O)c1cc2ccccc2[nH]1 +O=C(NC1(c2ccc(Cl)cc2)CC1)C1CCOCC1 +CCCNC(=O)C1CCN(S(=O)(=O)CC)CC1 +CN1C(=O)Cc2cc(C(=O)C3CCCCC3)ccc21 +CCCC(=O)N(C)CCc1noc(-c2cc3ccc(OC)cc3[nH]2)n1 +Cc1ccc2c(c1)NC(=O)c1cc(NC(=O)C3CC3)ccc1O2 +O=C1CCCc2cc(S(=O)(=O)NCCc3ccco3)ccc2N1 +COc1cccc(S(=O)(=O)C(C)C(=O)NC(C)c2ccccc2)c1 +Cc1ccccc1C(CC(=O)Nc1ccccn1)NC(N)=O +Cc1ccc(C(=O)OCC(=O)Nc2ccc(Cl)cc2Cl)o1 +CC(C)c1noc(CN2C(=O)c3ccccc3S2(=O)=O)n1 +COC1CCN(C(=O)c2c(C)noc2C)CC1Cc1ccccc1 +CC(C)Oc1cncc(C(=O)NCC(C)(O)c2ccc(F)cc2)c1 +COCC(C)(O)CNC(=O)Cc1ccc(Cl)cc1 +CCN(CC)C(=O)CN1CCCc2cc(F)ccc21 +CC(Nc1cnn(CC(=O)N2CCOCC2)c1)c1ccccc1F +Cc1ccccc1CCNC(=O)C(C)Sc1nccn1C +COc1cc(C)ccc1OCC(=O)NC(C)(C)C#N +CCC(C)(CC(=O)OC)NC(=O)c1scnc1C1CC1 +COc1cc(C2NC3(CCCC3)C(=O)N2C)cc(Cl)c1O +COC(=O)c1ccc(CN2CC(c3nc(C)no3)C2)cc1 +CC1(C)CN(CC(=O)c2cccs2)c2c(N)cccc2O1 +NC(=O)C1(CNC(=O)NCc2ccc3c(c2)OCO3)CCOCC1 +Cc1cc(NCc2ccc(F)cc2Cl)n2nc(C)nc2n1 +Cc1ccc2c(c1)c(=O)c(C(=O)NCCn1cccn1)nn2C +CC1CC(C)CN(C(=O)c2ccc(C(F)(F)F)cn2)C1 +C#CCOC(=O)c1ccc(NCc2c(C)noc2C)cc1 +CCCC(=O)Nc1cccc(Oc2ccc(C#N)cn2)c1 +COc1cc2[nH]c3c(N4CCCC(C)C4)ncnc3c2cc1OC +COCCn1cc(C(=O)N2CCC(N3CCNC3=O)CC2)ccc1=O +CC(=O)Nc1ccc(NC(=O)c2cccnc2N)cc1 +COCCN(C(=O)c1ccc(-c2cccc(C)c2)[nH]c1=O)C1CC1 +O=C(c1noc2c1CCCC2)N1CCC(Cc2cccc(CO)c2)C1 +CC(C)CNC(=O)c1ccc2c(c1)N(C)C(=O)CS2 +COc1cc(C)ccc1NC(=O)NCc1cn(-c2ccccc2)nn1 +CC(C)NC(=O)CNc1ccccc1C(F)(F)F +Cc1ccnc(C(NC(=O)c2ccc(=O)n(C)c2)C2CC2)n1 +CCOCCCNC(=O)NC(C)c1cc(C)sc1C +O=C(NC1(c2nc(-c3cnccn3)no2)CCCCC1)c1cc[nH]n1 +Cc1nc(CC(=O)Nc2cc(-c3cccs3)n[nH]2)cs1 +O=C(Nc1ccc(Br)cn1)c1ccnc(OC2CCC2)c1 +O=C(CNC(=O)c1ccoc1)NC1CCCNC1=O +CN(CCc1ccccn1)C(=O)c1cc2ccccc2s1 +Cc1ncc(C(=O)N2CCCCC2CCN2CCOCC2)s1 +Cc1cc(F)ccc1NC(=O)c1cc(C(N)=O)cn1C +O=C(CCc1ccc2cc[nH]c2c1)NCc1ccccc1 +CC(=O)Nc1cccc(C(=O)NCC2(c3ccccc3)CCC2)c1 +O=C(Nc1ccc(CO)cn1)c1ccc(F)c(F)c1 +COc1ccc(Cl)cc1S(=O)(=O)N(C)CC(=O)NC(C)C +O=C(Nc1ccccc1C(=O)N1CCCCC1)c1ccc2cc[nH]c2c1 +CCC(NC(=O)c1cccc(C(=O)OC)n1)c1ccc(Cl)cc1 +CCC(C(=O)N1CCC(NC(=O)c2ccoc2)CC1)c1ccccc1 +O=C(NCc1cc2ccccc2o1)Nc1ccncc1F +Cn1ccc(C(=O)N2CCCC(c3ccn[nH]3)C2)n1 +CCN(C(=O)c1scc2c1OCO2)c1ccccc1 +COc1cccc(NC(=O)c2ccccc2OC)c1 +CC(C)c1cc(C2CCCN2S(=O)(=O)c2ccccc2F)no1 +COCc1c(C(=O)N2CCN(C)CC2C)sc2ccccc12 +CC1CCCN(C(=O)NCC(c2cccc(F)c2)N2CCOCC2)C1 +CN(C)S(=O)(=O)c1ccc(=O)n(Cc2ccc(F)cc2)c1 +CC(=O)Nc1cccc(Nc2ncnc3sccc23)c1 +CCOc1ccccc1NC(=O)C(C)N1CCOc2ccc(N)cc21 +CCNC(=O)c1ccccc1NC(=O)c1ccccc1OC +CCc1noc(CN(C)C(=O)c2cnc(Cc3ccccc3)s2)n1 +O=C(Nc1nc[nH]n1)c1ccc(OC(F)F)cc1 +CC(C)N(Cc1ccccc1)C(=O)c1ccc2ncccc2c1 +CC(NS(C)(=O)=O)c1nc(C2CC2)nn1-c1ccc(Cl)cc1 +COCCn1cnnc1C(C)n1cnc2cccc(C)c2c1=O +COC(=O)c1ccc(NC(=O)CNc2cccc(OC)c2)cc1 +CC(C)(C)NC(=O)Nc1cccc(OCC2CCCO2)c1 +CCCOc1ccc(CNC(=O)Cc2ccc[nH]2)cc1 +COc1ccc(C2NC(=O)NC3=C2C(=O)N(CCCO)C3)cc1 +Cn1cnnc1CNc1ccc(C(F)(F)F)cn1 +CCOc1cccc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)c1 +O=S(=O)(c1ccc(F)cc1Br)N1CCOCC1 +CCNC(=O)CNC(=O)NC(C)c1cnn(Cc2ccccc2)c1 +COc1ccc(OC)c(CN(C)C(=O)c2ccc(=O)n(C)n2)c1 +Nc1nc(NCCO)cc(-c2cccc3cnccc23)n1 +COc1ccc(C)cc1NC(=O)COC(=O)c1ccccc1C +CCOc1c(OC)cc(CNS(C)(=O)=O)cc1OC +CC1CN(C(=O)CCNC(=O)OC(C)(C)C)c2ccccc21 +CC(CS(=O)(=O)N1CCNCC1)C(=O)Nc1ccc(F)cc1 +Cc1cc(=O)c2cc(NC(=O)c3ccco3)ccc2[nH]1 +COc1cccc(C(=O)N2CCN(c3ccccc3)CC2)c1O +O=C(NCc1ccco1)NCc1ccccc1OCc1ccccc1 +CSc1ccccc1NCC(=O)NC1CCN(C(C)=O)CC1 +Cc1noc(C)c1C(=O)NC(C)c1cccc(OC(C)C)c1 +COc1ccc(CCNC(=O)CN2CCOCC2C2CC2)cc1 +CC(C)(C)c1cc(C(=O)N2CCc3ccccc3C2)ccn1 +COc1ccc(CNC(=O)N2CCN(c3ncncc3C)CC2)cc1 +O=C(NCCCn1cnc2ccccc21)c1ccc(-n2cncn2)cc1 +Cc1ccc(-n2c3c(cc(C#N)c2=O)C(=O)CCC3)cc1C +CN(CCC(O)c1ccc2c(c1)OCCCO2)c1ccccc1 +Cn1cnnc1CNC(=O)Cc1cccc(OCC#N)c1 +Cc1ccc(CC2(NC(=O)Cc3c[nH]c(=O)n(C)c3=O)CC2)cc1 +CC(OCC1CCCO1)C(=O)NC1CCOc2c(Cl)cccc21 +Cc1ccc(OC(C)C(=O)NCc2cn[nH]c2)cc1 +CC(C)(C)c1nc(CN2CCN(C(=O)C3CCCO3)CC2)cs1 +COc1cccc(C(=O)n2nc(-c3cccc(C)c3)nc2N)c1 +CCOC(=O)CN(CC)C(=O)Cc1ccc(C)cc1 +CCc1cc(C(=O)N2CCc3ccc(Cl)cc3C2)[nH]n1 +Cc1cnc(CCNC(=O)NC2CC(C)(C)OC2(C)C)s1 +CCCCc1nc2cc(NC(=O)COC)ccc2[nH]1 +COc1cccc2c1C(C(=O)c1cccs1)NCC2 +CCCC1CCC(NC(=O)CCc2nc(-c3ccncc3)no2)CC1 +N#CC1C=CC(C23CC4CC(CC(C4)C2)C3)=NC1=O +CCc1ccccc1N1CC(C(=O)N(C)CC(=O)N(C)C)CC1=O +COc1ccc(C)cc1NC(=O)C1CC2CCC1O2 +CN(Cc1ccc(Cl)cc1)C(=O)c1cc(F)cc(F)c1 +Cc1ccc(C)c(S(=O)(=O)N(CCCO)C(C)(C)C)c1 +Cc1nc(C2(NC(=O)c3cc4ccccc4c(=O)[nH]3)CCCC2)no1 +Cc1ccc2c(c1)CCC2NC(=O)c1ccncc1 +CC(C)c1nc(CNC(=O)c2ccc(N3CC(O)C3)nc2)no1 +CCc1nnsc1C(=O)NC(C)c1ccc(F)cc1 +CC1CN(C(=O)c2cc(S(=O)(=O)N3CCCC3)c[nH]2)CC(C)O1 +CC(O)c1ccc(Oc2cccc(CO)c2)c(F)c1 +CC(C)n1c(CC(F)(F)F)nc2cc(O)ccc21 +Fc1ccc(N2CCC(CN3CCOCC3)CC2)nc1 +CCOC(=O)C1=C(C)C(NC(=O)Nc2ccc(Cl)cc2)=NC1C +COCc1nc(Cn2ccc(-c3cccc(-c4ccncc4)c3)n2)no1 +N#Cc1ccc(C(=O)NCC(=O)Nc2ccc(F)c(C#N)c2)cc1 +Cc1ccc(C(C)NC(=O)CCn2nc3ccccn3c2=O)cc1F +COC(=O)CCN(C)S(=O)(=O)c1cccc(F)c1 +O=C(NCc1ccccc1COCC1CC1)c1[nH]cc2c1CCC2 +CNC(=O)NCC(=O)Nc1ccc(NCC2CCCO2)c(F)c1 +CCCc1noc(C2CCCN(S(=O)(=O)c3cccs3)C2)n1 +Cc1nc(-c2cccc(NS(=O)(=O)c3c(C)noc3C)c2)cs1 +CCOc1ccc2c(c1)cc(C(=O)N1CCOCC1)n2C +COc1cc2nc3n(c2cc1OC)C(O)C=C(c1ccccc1)S3 +CCN1CCOC(CC(=O)Nc2ccc3c(c2)OCO3)C1=O +CCCOCC(=O)Nc1cc(C(=O)Nc2ccccc2)ccc1Cl +COc1cc(CNC(=O)Cc2ccn(C)c2)cc(OC)c1 +CCC(Nc1ccc(CC(N)=O)cc1)C(=O)Nc1cc(C)on1 +COc1cccc2c1OC1(C)CC2NC(=O)N1c1cccc(C)c1 +COCC1(CNC(=O)c2cccc(OC)c2)CC(O)C(O)C1 +O=C(c1n[nH]c2c1CCC2)N1CCn2cccc2C1c1ccccc1 +CN1C(=O)c2ccccc2C1(O)c1ccc(Cl)cc1 +Cc1ccc(-c2nnc(CCC(=O)NCc3cc(C)oc3C)o2)cc1 +CC(=O)c1ccc(NC(=O)c2cnn3c4c(cnc23)CCCCC4)cc1 +CC1CCCCC1N(C)C(=O)COc1ccc(Cl)cc1C(N)=O +CN(C)C(=O)C1CCN(C(=O)c2cc(Cl)ccn2)CC1 +CCCS(=O)(=O)NCCc1ccn(-c2ccccc2)n1 +COCC(=O)N1CCCc2ccc(NC(=O)Nc3ccccc3)cc21 +COC(=O)C(O)(c1cc(C)c(O)c(C)c1)C(F)(F)F +N#Cc1ccc(OCCSc2ccc(N)nc2)cc1 +Cn1c(=O)[nH]cc(C(=O)NCc2nc3ccccc3[nH]2)c1=O +CC(C)Oc1ccc(NC(=O)c2cc(Cl)c[nH]2)cc1 +Cc1ccc(C(=O)N2CCC(Oc3c(C)cccc3C)CC2)c(=O)[nH]1 +N#Cc1ccc(S(=O)(=O)c2ccc(C#N)cc2)cc1 +CCCCOc1ccc(-c2c[nH]c(N)c2C#N)cc1 +O=c1n(CCSc2nnnn2C2CCCC2)nc2ccccn12 +Cc1cc(NS(=O)(=O)c2ccccc2C)ccc1N +CC(NC(=O)Cn1nnc2ccccc21)c1nc(C(C)(C)C)cs1 +CCOc1ccc(F)c(C(=O)NC2CCCC(C(N)=O)C2)c1F +CCCCOc1ccc(-c2nnc(CN3CCOC(C)C3)o2)cc1 +Clc1cccc(-c2nn(-c3ccccn3)c3c2CNCC3)c1 +CC(C)c1ccccc1OCCNS(=O)(=O)c1ccc(N)cc1 +O=C(c1ccc(=O)[nH]c1)N1CCc2onc(-c3cccc(F)c3)c2C1 +Cc1ccc(OC2CCN(C(=O)c3cc(C(C)C)[nH]n3)CC2)cc1C +COc1cccc(CCC(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)c1 +CNS(=O)(=O)c1ccc(NCC2CC2)c(N)c1 +COc1ccccc1NC(=O)c1cc2cccnc2nc1N +CN(C)C(=O)c1ccc(CN(C)C2CCCN(c3ccccc3)C2)[nH]1 +CCN(C)C(=O)C1CCC(CNC(=O)OC(C)(C)C)O1 +Cc1cc(-c2nn3c(-c4cc(F)ccc4F)nnc3s2)[nH]n1 +COC(=O)Nc1cc(NC(=O)c2ccc(F)cc2Cl)ccc1F +Cc1ccc(NC(=O)Nc2cccnc2)cc1Cl +CCCS(=O)(=O)NCc1ccc(OC)cc1OC +C#Cc1cccc(NC(=O)CNS(=O)(=O)c2c(C)noc2C)c1 +Cc1nc2cc3c(cc2n1-c1ccccc1)OCCO3 +O=C(Cc1cccc(NC(=O)c2ccc3cncn3c2)c1)NC1CC1 +CCCCN(CCO)C(=O)Nc1ccc(F)cc1C +O=C(c1ccc(OC(F)F)cc1)N1CCCCC1CCn1cccn1 +N#Cc1ccc(C2NCCc3c(N)cc(F)cc32)cc1F +Nc1nocc1Cc1ccc(Br)cc1 +Cc1nc(CNc2ccc(F)cc2F)sc1C +Cc1nccc(CNc2cccc(C(N)=O)c2C)n1 +Cc1cc2nc(C)c(CCC(=O)NCCS(N)(=O)=O)c(C)n2n1 +COCc1c(C(=O)NCC(F)(F)F)sc2ccccc12 +Cc1noc(C)c1S(=O)(=O)N1CCCC1c1ccccc1F +O=C(CC1=CCCCC1)N1CCC2(CC1)COC(COCC1CC1)C2 +CCc1nc2n(n1)CCCC2NC(=O)N1CCC(C(=O)OC)CC1 +O=C(Oc1ccc(-n2cnnn2)cc1)c1ccc(Cl)cc1 +CCN(CC(F)(F)F)S(=O)(=O)c1cc(N)ccc1Cl +CCc1nc(C)ccc1OCc1nc(C2CCOC2)nn1C(C)(C)C +Cn1cc(C(O)CNC(=O)Nc2ccc(F)cc2)c2ccccc21 +O=C(CSc1nccnc1Sc1ccccc1)NC1CC1 +CC(=O)Nc1ccc(CC(=O)Oc2ccccc2)cc1 +CCc1nnc(NC(NC(=O)N(C)C)C(Cl)(Cl)Cl)s1 +CCOc1cc(C)c(S(=O)(=O)N(C)C)cc1C +Cn1ccnc(NC(=O)Cc2ccc(F)c(Br)c2)c1=O +Cc1cccc(-c2nnc(COC(=O)Cc3cccs3)o2)c1 +O=C(NCCc1ccccc1)C1(n2cnnn2)CCCCC1 +COc1ccccc1S(=O)(=O)Cc1cccc(C(N)=O)c1 +Cc1cc(NC(=O)NC(C)CCc2ccc(O)cc2)n(C)n1 +NC(=O)c1ccc(C(=O)OCC2CCN(c3ccccc3)C2)cc1 +C=CCCC(=O)N1CCCN(C(=O)CCC=C)c2ccccc21 +CCOc1ccccc1C(=O)NCC(=O)N(C)Cc1cccnc1 +CCCNC(=O)COc1ccc(Cl)cc1Br +CSc1ccccc1NC(=O)c1cn(CC(=O)N(C)C)nn1 +O=C(CCc1ccccc1)N1Cc2ccccc2C(n2cccn2)C1 +CCCc1cc(C(=O)N2CCCC2c2cccnc2)[nH]n1 +O=C(COc1ccc(F)cc1)NCC(O)C1CCCCC1 +COc1cccc(-c2noc(N3CCCC3)n2)c1OC +O=C(c1ccsc1)N1CCC(S(=O)(=O)c2ccccc2)CC1 +Cn1cc(C(=O)NCC(=O)Nc2ccc(F)cc2)c(=O)c2cccn21 +NC(=O)C1CCCN(C(=O)c2ccc(Cl)cc2)C1 +CCc1n[nH]c(C2CN(Cc3nc4ccccc4n3C)CCO2)n1 +Cc1ccc(NC(=O)CN(C)Cc2cnc(C(C)C)s2)nc1 +NC(=O)c1ccc(NC(=O)CNc2ccc(Cl)cc2)cc1 +CCc1ncc(C(=O)N(C)CC2Cc3ccccc3CN2C)cn1 +O=C1Nc2ccc(-c3cccc(C(F)(F)F)c3)cc2C1=O +C=CCNC(=O)Cn1c(C(C)NC(C)=O)nc2ccccc21 +CC(=O)NC1c2ccccc2C2CN(C(=O)c3ccc(N)cc3)CC21 +CCc1ccc(C2COCCN2C(=O)NC(C)CCCO)o1 +COc1cccc(-c2nnc3sc(-c4cnccn4)nn23)c1 +CCOC(=O)N1CCN(S(=O)(=O)NCC2CC2)CC1 +Cc1ccc(C(=O)NCC(=O)NCCOc2ccccc2)cc1C +COc1cccc(Cn2c(CNC(=O)C3CC3)nc3cccnc32)c1 +Cc1ccccc1Cn1ccc(NS(=O)(=O)c2c(C)n[nH]c2C)n1 +O=C(c1sc2ccccc2c1Cl)N1CCCC(c2nc[nH]n2)C1 +COc1ccc2c(C)c(CC(=O)NC(C)CO)c(=O)oc2c1OC +CN(Cc1nnc2ccccn12)C(=O)CNc1ccccc1Cl +CC(C)c1c(CO)nnn1-c1ccc2c(c1)OCO2 +O=C1c2ccccc2S(=O)(=O)N1Cc1ncc(-c2ccccc2)o1 +CNC(=O)c1ccc(OC)c(NCC(=O)NCc2ccccc2F)c1 +Cc1nc(COc2ccccc2)sc1C(=O)NCc1ccncc1 +CNC(=O)c1cnc(C=Cc2cc(C)ccc2F)[nH]c1=O +O=C(CC1CCCO1)NCc1noc(-c2ccco2)n1 +CCCNc1nc(C)nc2c1cnn2CCc1ccccc1 +CCC(=O)Nc1ccc2c(c1)CC(C(=O)NC1CCCC1)CO2 +COc1ccnc(NC(=O)CC(C)c2ccc(F)cc2)c1 +CCC(O)c1cc2c(c(C)c1Cl)NC(=O)C2CC +CN(C)S(=O)(=O)c1csc(C(=O)NC2CCCCCC2)c1 +Cn1c(SCC(=O)NC(C)(C)C)nc2ccccc21 +CCn1ncc(Br)c1C(=O)N(C)Cc1cnn(C)c1C +CC(C)(C)c1ncc(CN2CCC(O)(C(F)(F)F)C2)s1 +O=C(c1ccc(F)cc1)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +Cc1ncc(CNC(=O)CSc2nnnn2C2CCCC2)s1 +Cc1nnc(CCNc2ncnc3c2Cc2ccccc2OC3)s1 +COc1c(OC(F)F)ccc2c1C(C1CC(=O)C1)NCC2 +CCC(C)C(NS(=O)(=O)c1ccc(Cl)c(Cl)c1)C(N)=O +CCCS(=O)(=O)NC1CCN(C(=O)NCC)CC1 +CCSc1ccccc1NCc1nnc(C2CC2)o1 +CCc1cccc(C)c1NC(=O)Cc1cccc(F)c1 +CCCn1cc(N)cc1C(=O)N1CCCCC1CO +O=C(c1ccc2c(c1)CCC2)N1CCN(Cc2ccccc2F)CC1 +CCCNC(=O)C(C)Sc1nc(C)c(C(C)=O)cc1C#N +c1ccc(C2(c3ccccc3)OCC(Cn3cncn3)O2)cc1 +COc1ccc(NC(=O)Cn2cc(Cl)cn2)c(N)c1 +COCCN(Cc1ccc(F)cc1Cl)C(=O)Nc1cc(C)on1 +Cc1cc(C)n(C(C)CC(=O)N2CCCC2c2cnn(C)c2)n1 +CN(C)c1ccc(C(=O)Nc2ccccc2F)cc1 +Cc1cccc(C(=O)Nc2nn(C)c3c2C(C)CC(=O)N3)c1 +Cc1cn(Cc2ccc(Cl)cc2)c(=O)[nH]c1=O +Cc1cc(NC(=O)CN(c2ccccc2)C(C)C)no1 +CC(C)(C)C(O)CCNC(=O)C1(c2cccs2)CC1 +Cc1c[nH]c(CN2CC(C)C(O)(C3CCC3)C2)c(C)c1=O +Cc1cc(N2CCC(c3nn(C)c4ncccc34)C2)ncn1 +CC(C)CCn1nc2c(c(CC#N)c1=O)CC(C)CC2 +Nc1cnnc(-c2ccc(OC3CCCC3)cc2)n1 +CN(C)C(=O)Cn1c(=O)n(C2=CCCCC2)c2ccccc21 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)Nc1ccc2c(c1)COC2 +Nc1c(-c2ccncc2)nnn1-c1ccc(Cl)cc1 +Cn1c(CNCc2cccc(Cl)c2)nc2ccccc21 +C=CCn1c(C)nnc1SCC(=O)Nc1ccc(F)cc1 +CCOC(=O)c1cc(C)sc1NC(=O)c1scnc1C1CC1 +O=C(NCc1ccco1)c1cccc(CNc2ccc(F)cc2)c1 +CC(=O)c1cccc(OC(=O)CCn2cnc3ccccc3c2=O)c1 +CC(Oc1ccc(Cl)cc1C(N)=O)C(=O)Nc1cccc(C#N)c1 +Cc1cccc(C)c1NC(=O)NC(C)c1ccc(C#N)cc1 +Cc1ccc(NC(=O)C(O)c2ccccc2)cc1C +Cc1cccc(OCC(=O)N2CCN(C3CCC(C)CC3)CC2)c1 +CCc1cccc(NC(=O)C2CCN(C(C)=O)CC2)c1 +CCS(=O)(=O)c1ccc(-c2cccc(NC(=O)C3CC3)c2)nn1 +COC(=O)N(C)c1ccc(NS(=O)(=O)c2ccc(C)cc2C)cc1 +COCCN1CC(C(=O)Nc2cccnc2)CC1=O +O=C(CNc1ccccc1F)c1ccc2c(c1)OCCO2 +C=CCn1c(C)nnc1SCc1nc2c(C)cccc2c(=O)[nH]1 +CN(CC(=O)Nc1cccnc1)c1ccc(Cl)cn1 +CC(NC(=O)CSc1cccc2cccnc12)c1ccccc1 +CCn1cc(NC(=O)N2CCCCC2CCNS(C)(=O)=O)cn1 +CCN(Cc1ccco1)C(=O)Nc1cccc(F)c1 +Cc1ccc2c(c1)nnn2C(=O)NC1CCCCC1 +Cc1nccn1-c1ccccc1CNc1ccc2cc[nH]c2n1 +Cc1cc(C)n(C(C)C(=O)N2CCCC2c2ccncc2)n1 +Nc1cc(F)cc2c(=O)cc(C(=O)N3CCCCCC3)oc12 +Cc1nc(C)c(CC(=O)N(C)Cc2ccc3c(c2)OCO3)c(=O)[nH]1 +CN(C)C(=O)N1CCC2(CCN(Cc3cccc(F)c3)C2=O)C1 +COc1ccc(C)cc1C(=O)COc1cccc(C#N)c1 +CC(C)n1cnc2cc(C(O)Cn3cc(N)cn3)ccc21 +CCN1CC(C(=O)Nc2ccccc2NC(=O)N2CCCC2)CC1=O +Cc1oncc1C(=O)N(Cc1cccs1)Cc1cccn1C +Cc1nn(C)cc1C(=O)Nc1cc(Cl)cc(Br)c1O +CCOc1cc(CNC(=O)C2CCCN2C(=O)C(C)C)ccc1OC +O=C(CSc1ncccn1)NCCc1ccc2c(c1)OCCO2 +CNC(=O)NCC(=O)N1CCOCC1CC(C)C +CN(CCCNC(=O)c1cccc(C#N)c1)c1ccccc1 +C=CCOc1cccc(NC(=O)NCC(=O)N(C)C)c1 +CCC(=O)Nc1ccc2c(c1)CC(C(=O)NC(C)C)CO2 +CCC(=O)NC1CCOc2c(CC)cc(C(O)C(C)C)cc21 +Cc1cc(C)n2nc(C)c(C(=O)OCc3ccc(C(N)=O)cc3)c2n1 +CCc1c(C(=O)n2nc(C)cc2C)cnn1-c1ccccn1 +CCC(NC(=O)Cc1ccc[nH]1)c1ccc(Br)cc1 +CCn1cc(NS(=O)(=O)c2ccccc2N)cn1 +COCCn1c(CCNC(=O)c2ccc(F)cc2)nc2ccccc21 +CCOC(=O)c1sc(N(C(=O)c2ccc(CC)o2)C2CC2)nc1C +Cn1c(SCC(=O)Nc2ccccc2)nc2ccccc2c1=O +Cc1cc(CN(C)C(=O)c2ccc(Cl)cc2N)no1 +O=C(CCc1ccccc1O)N1CCN(Cc2ccccn2)CC1 +Cc1nc(CNC(=O)Cc2csc(C(C)C)n2)c(C)s1 +CN(C)C(=O)N1CCc2onc(C(=O)N3CCCC3)c2C1 +COc1ccc(NC(=O)C2CC(=O)N(C)C2)cc1C +CC(C)CC(=O)NCc1nc(-c2cccs2)no1 +CCOC(=O)C1(O)CCN(C(=O)Cc2ccccc2C)CC1 +COc1cccc(C2C(c3nc(N(C)C)no3)CC(=O)N2C2CC2)c1 +CCCCOc1ccccc1NC(=O)N(C)Cc1cnn(C)c1 +CCCCNC(=O)c1csc(Nc2ccccn2)n1 +O=C(c1cc(F)ccc1F)N1CCN(CCO)CC1 +O=C(c1ccc(F)c(Cl)c1)N1Cc2ccccc2C(O)C1 +Cc1ccnn1CCC(=O)N1CCC(O)(c2cccnc2F)CC1 +CC(C)(C)CC(O)CNC(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +O=C(NCC1CC1)c1cc(-c2cc[nH]n2)n2ccccc12 +N#CC(c1cccs1)N1CCN(Cc2ccccc2)CC1 +Cc1noc(C2(C)CCCN(C(=O)c3cscn3)C2)n1 +Cc1cn(CC(=O)NCC2CN3CCCC3CO2)c2ccccc12 +Cn1ncc2c(SCc3nnnn3C3CC3)ncnc21 +C=CCN(CC(=O)Nc1ncc(C)s1)C(=O)C1CCCCC1 +CC(=O)N1CCN(Cc2ccccc2)CC1C(=O)NCc1ccco1 +CCOC(=O)C1=C(CN2CCN(CC(F)F)CC2)NC(=O)NC1 +Cc1nc(C(=O)N2CCCc3cc(Br)ccc32)cs1 +COc1ccccc1OC(=O)c1cc(Cl)ccn1 +O=C1CN(C(=O)c2cc(Br)cn2C2CC2)CCN1 +CCOc1ncccc1CNCc1csc(C(C)(C)C)n1 +Cc1ccc(-n2ncc3c2NC(=O)CC3c2ccc(F)cc2)cc1 +Cn1c(CSc2ccccn2)cc(=O)n(C)c1=O +Cn1nccc1C(=O)Nc1nc(-c2ccccc2)cs1 +Cn1ncc2c1CCCC2NC(=O)NCC1CCCc2ccccc21 +CSc1ccc(C(=O)NCCOCC(F)(F)F)cc1 +COc1cccc(Nc2ncnc(NC3CCCC3)c2N)c1 +O=C(Cn1cccn1)N1CCC2(CCCNC2=O)C1 +Cc1ccc(Cl)cc1-c1cnn(C)c(=O)c1CC#N +Cc1cc(C(=O)Nc2c(C)n[nH]c2C)c2c(C)noc2n1 +CC(C)c1ccccc1-n1nnc(-c2ccco2)c1N +CCCC(=O)Nc1ccc(C(=O)NCc2ccco2)cc1 +Cc1ccc(S(=O)(=O)NCc2ccc3c(n2)CCCC3=O)c(F)c1 +Cc1n[nH]c(=O)n1-c1ccc(Oc2ccccc2)cc1 +COc1c(Cl)cc(Cl)cc1CCOC(=O)CN +CCCNC(C#N)CCSc1nc(C)cc(C)n1 +N#CC1(NS(=O)(=O)c2ccc(N3CCCC3=O)cc2)CCOCC1 +CC(O)CNC(=O)C(NC(=O)Cc1ccccc1)C(C)C +Cc1n[nH]c(C(=O)N(C)CC2CCCCO2)c1Br +Cn1cc(CNc2cccc(F)c2)c(-c2cccnc2)n1 +CCCn1c(C)c(CC(=O)N2CCOCC2)c2c1CC(C)(C)CC2=O +CCOc1ccccc1OCC(=O)Nc1cccc(C)c1 +Cc1nc(CNC(=O)Cc2ccccc2OC(C)C)c(C)s1 +Cc1nn(-c2ccccc2)c(C)c1S(=O)(=O)NCc1ccco1 +O=C(Nc1ccccc1)Nc1nnc(-c2ccco2)o1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1cc(Cl)ccn1 +COc1cc(OC)c(-c2cc(=O)c(C#N)c[nH]2)c(OC)c1 +O=C(CCCc1ccccn1)Nc1cc(N2CCCC2=O)ccc1F +Cc1nc(C)c(C(=O)OCC(=O)c2ccc3c(c2)CCC(=O)N3)s1 +CN(C)C(=O)NCCOC(=O)Nc1ccc(Cl)cc1 +CC1CN(C(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)C(C)CO1 +CCNC(=O)CN(C)C(=O)Cc1ccc(Cl)c(Cl)c1 +Cc1nc2cc(C(=O)NCc3ccncc3)ccc2n1-c1ccccc1 +Cc1nc(NCCSc2nnnn2C)c2ccsc2n1 +COc1cc(C)sc1C(=O)OCCNC(=O)c1cccnc1 +COC(=O)NCC(=O)Nc1cc(Cl)ccc1O +Cc1ccc(C(=O)NCc2ccc(Cn3cccn3)cc2)cc1 +CC(OCC(F)(F)F)C(=O)NCC1CCCO1 +Cc1cc(CNC(=O)c2ccc(N3CCOC3=O)cc2)c(C)o1 +O=C(Nc1nc2c(s1)CCC2)c1cc(-c2ccco2)[nH]n1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NC(C)c1cnn(C)c1C)O2 +Cn1cc(C(=O)c2ccccc2)c(=O)c2ccccc21 +CC1CCN(C(=O)CSc2nc(=O)n3ccccc3n2)CC1 +O=C(CSc1ccncc1)Nc1cc(F)c(F)c(F)c1 +Cc1cc(C(=O)CSc2nc(N)c3ccsc3n2)c(C)n1C +O=C(Nc1nc(-c2ccc3c(c2)OCO3)cs1)C1CC1 +CCCN1C(=O)C(C(C)C)Oc2c(OCC)cc(CO)cc21 +O=C(c1ccsc1)N1CCC(Oc2nncc3ccccc23)CC1 +CC(O)CNS(=O)(=O)c1ccc2c(c1)N(C)C(=O)CO2 +O=C(Nc1nnc(C2=COCCO2)o1)c1ccccc1Cl +Cn1nc(CNc2ncccn2)c2c1CN(Cc1ccncc1)CC2 +Cc1cc(NC2CCc3ncnn3C2)n2nc(C(F)(F)F)nc2n1 +CC(Cn1ccnc1)NC(=O)c1cc(Br)cnc1N +COc1cc2c(c(OC)c1)C(Cn1cnnn1)NCC2 +CC(C)CC(=O)N1CCC(NC(=O)Cc2c[nH]c3ccccc23)CC1 +CCCCn1c(N)c(N(Cc2ccccc2)C(=O)CC)c(=O)[nH]c1=O +CC(C)(CNC(=O)c1ccc2c(c1)CCC2)N1CCOCC1 +CCN(C(=O)Nc1cccc(C(N)=O)c1)C(C)C(C)C +O=C(NCCOc1cccc(Cl)c1)NCc1ccsc1 +CC(C)(C)C(NCc1ccc(F)cc1F)C(N)=O +CCc1cc(N2CC(C)C(O)(C(C)C)C2)nc(N2CCOCC2)n1 +Cc1cnc(N2CC3CN(Cc4nccs4)CC3C2)nc1 +COc1ccc(-c2csc(N3CCCC3=O)n2)cc1OC +C(=CC1NCCc2cc3c(cc21)OCO3)c1ccncc1 +Cc1ccc(-c2csc(NC(=O)c3cc(C(N)=O)cs3)n2)cc1 +CCS(=O)(=O)N1CCCc2ccc(NC(=O)CC(C)C)cc21 +CC(NC(N)=O)C(=O)Nc1cccc(C(F)(F)F)c1 +CC(C)(C)C(=O)NCCC1CN(Cc2ccccc2F)CCO1 +CCOC(=O)c1cc(C)n(CC(=O)Nc2ccc(C(N)=O)cc2)c1C +COc1ccccc1NC(=O)CSc1ncnc2ccccc12 +CN(Cc1cccn1C)C(=O)CNC(=O)c1ccc(F)c(F)c1 +Cc1nc(C(=O)Nc2ccc(-n3cccn3)nc2)cs1 +O=C(CSc1nnc(CO)n1C1CC1)Nc1ccc(F)cc1F +CCCC1CCCN(C(=O)c2c(C)nsc2NC)CC1 +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1cc(Cl)ccn1 +NC(=O)C1CN(C(=O)c2ccc3cc[nH]c3c2)CCO1 +COc1ccc(NC(=O)c2ccc(NC3CC3)nc2)c2cccnc12 +CSc1ccc(Cl)cc1NC(=O)c1ccc(-n2ccnn2)cc1 +Cc1occc1C(=O)N1CCCCC1c1nc(C(C)C)no1 +COc1ccc(CCC(=O)Nc2cccc(F)c2)cc1N +c1ccc(-c2nc(-c3cccnc3)cc(N3CCOCC3)n2)nc1 +O=C(Nc1ccc2c(c1)COC2)c1ccc(-n2cccn2)c(F)c1 +Cc1ccc(C(=O)Nc2ccc(Cl)cc2N)cn1 +O=C(c1ccccc1)N1CCOC(COc2cccc(F)c2)C1 +NC(=O)c1ccc(NC(=O)COc2ccc3ccccc3c2)c(F)c1 +O=C(NCc1csc(=O)[nH]1)c1cc2cc(F)ccc2oc1=O +COc1ccc(CCCNC(=O)c2ccc(-c3cccnc3)nc2)cc1 +O=C(Cc1c(F)cccc1F)Nc1cccc(Cn2cccn2)c1 +COc1cc(C(=O)Nc2nc[nH]n2)cc(OC)c1C +CC(=O)c1sc(NC(=O)C2COc3ccccc3O2)nc1C +CCCCNc1nc2c(c(=O)n(Cc3ccccc3)c(=O)n2C)n1C +Cc1nc(C2CCCN(C(=O)C3CCC(=O)N3)C2)sc1C +COC(C)C(=O)Nc1ccc(C(F)(F)F)cc1N +CCc1noc(CC)c1CNC(=O)CCn1c(=O)oc2ccccc21 +CC(NC(=O)N(CCO)C1CC1)c1ccc2ccccc2c1 +O=C(Cn1cc(Cl)c(=O)[nH]c1=O)c1cccc(C(F)(F)F)c1 +COCc1nc(COc2ccc(OC)cc2)sc1CC#N +COC(=O)CCNc1sc2c(c1C(=O)OC)CCCC2 +Cc1ccc(NC(=O)CSc2nc3n(n2)CCCCC3)c(C)c1 +CS(=O)(=O)N1CCN(c2ccccc2N)CC1 +CS(=O)(=O)N1CCC2OCCCC2(COc2ncccc2F)C1 +CCNC(=O)COc1cccc(NC(=O)Nc2ccccc2)c1 +CC(=O)NCCNC(=O)CCn1c(C)cc2ccccc21 +C#CCNC(=O)CSc1nccn1-c1cccc(OC)c1 +Cc1noc(C)c1C(=O)Nc1nc(-c2cccc(Cl)c2)ns1 +CN(Cc1cccc(Cl)c1)C(=O)NCCC(=O)N1CCCC1 +FC(F)(F)c1ccnc(NCc2cc(-c3ccccn3)no2)n1 +Cc1nc(CN(C)C(=O)Nc2ccn(-c3ccccc3)n2)cs1 +Cc1ccc(S(=O)(=O)N2CCCCC2CCC#N)c(C)c1 +Cc1cc(Cl)c(NC(=O)NCc2ncc[nH]2)cc1Cl +N#Cc1ccc(CSc2nc(N)c(C#N)cc2C#N)cc1 +CC(=O)Nc1ccc(OCc2cn3ccccc3n2)cc1 +Cc1ccc(C(N)=O)cc1NC(=O)NC(C)c1ccc(Cl)cc1 +Cc1ccc(Cl)cc1N1CCN(C(=O)Nc2nncs2)CC1 +CC(COc1ccc(F)cc1)NC(=O)NC(C)C(C)C +CC(C)c1noc(CCCNC(=O)N2CCOCC2C2CC2)n1 +CC(=O)Nc1ccc(OC(=O)CCc2nc3ccccc3s2)cc1 +Cc1c(C#N)c(N)n(CCc2ccc(Cl)cc2)c1C +CC(=O)c1cccc(N(CC(=O)NC2CC2)S(C)(=O)=O)c1 +COC(=O)CCC(=O)Nc1nc(-c2ccc3c(c2)CCO3)cs1 +C=CCNC(=O)N1CCN(C(=O)c2ccc(Cl)cc2F)CC1 +COc1cccc(C(=O)NCC(CC(C)C)N2CCOCC2)c1O +CCNc1ccc(C(=O)NCCCS(N)(=O)=O)cc1 +CC(=O)c1ccc(NC(=O)CNC(=O)C2CCCC2)cc1C +COc1cc(OC)cc(C(=O)N(C)Cc2cccnc2)c1 +COc1ccc2c(c1)OCC(C(=O)N1CC(n3nc(C)cc3C)C1)C2 +Cc1cc(OCC(=O)NCc2ccco2)nc(N2CCCC2)n1 +CC(C(=O)Nc1ncccn1)N1CCOC(Cn2cccn2)C1 +Cc1ccc(S(=O)(=O)N2CCC(O)CC2)c(Br)c1 +CCC(=O)Nc1cccc(NC(=O)c2cccn2C)c1 +C=CCn1c(SCc2nc(C3CC3)no2)nnc1-c1ccccc1 +Cc1ccc(NC(=O)C(C)C)cc1NCC(=O)N1CCCC(C)C1 +O=C(NCc1ccco1)c1cn2c(n1)CCC(c1ccccc1)C2 +O=C(COc1ccccc1)NCc1ccc(C(F)(F)F)cc1 +CCNC(=O)c1ccc(NC(=O)C2CCCC2)c(C)c1 +Cc1n[nH]c(SCC(=O)Nc2nnc(CC(C)C)s2)n1 +COc1ccc(CC(=O)NCC#Cc2ccc(C(C)=O)cc2)cc1 +Cc1cc(C(C)Nc2ccc3nnnn3n2)c(C)s1 +CCN(Cc1ccccc1)C(=O)C1(C#N)CCCC1 +CC(C)CNC(=O)C1CN(S(=O)(=O)C2CC2)C1 +CCNC(=O)N1CCC(NC(=O)Nc2c(C)noc2CC)C1 +O=C(Nc1ccccc1)C1CCCN(C(=O)CCc2cccs2)C1 +CC(=O)c1cccc(OCC(=O)Nc2cnn(C)c2)c1 +CCCCOc1ccc(CNc2nncs2)cc1 +CC1c2cccn2CCN1CC(=O)NC1(C#N)CCCC1 +Cc1c(C(=O)Nc2nccs2)nnn1-c1ccc(F)cc1 +O=C(Nc1ccccc1F)c1cc(O)c(OCc2ccccc2)cn1 +COc1ccc(NC(=O)Nc2ccc(OC)c(F)c2)cc1F +CC1CCCCC1OCCNC(=O)c1cc2c([nH]c1=O)CCCC2=O +CCOc1cc(NC(=O)N(C)Cc2cc(C)on2)ccc1OC +Cc1cc(F)ccc1NC(=O)Cn1ccc2c(=O)[nH]ccc21 +O=C(Cc1nc2ccccc2o1)NCc1ccc2nonc2c1 +CCOC(=O)C(Cc1c(Br)cnn1C)NC +CC1CCC(NC(=O)Cc2csc(-c3ccccn3)n2)CC1 +Cc1nccn1S(=O)(=O)c1ccc(Br)cc1 +CN(C)c1ccc(C(=O)NCc2ccc(-n3cccn3)nc2)cc1 +Cc1ccc(-c2nn3cnnc3s2)cc1NC(=O)c1cccs1 +CCOc1ccccc1OCCCC(=O)N1CCC(O)CC1 +C=CCNC(=O)c1c[nH]nc1-c1ccc2c(c1)OCCO2 +O=C(NCc1ccccn1)c1c(O)cc(F)cc1F +CC(=O)Nc1ccc(NC(=O)c2cccc(OC(C)=O)c2)cc1 +COCc1ccccc1C(=O)NC1CCN(C(=O)OC(C)(C)C)CC1 +Cc1cnc(C(=O)NCc2ccc(C(F)(F)F)cc2)cn1 +CCOC(=O)c1cc(-c2ccccc2OCC)nc(N)n1 +CC(C)N(C)C(=O)NCC(C)N1CCOCC1C +O=C(NC1CCCCNC1=O)c1cc(-c2ccco2)[nH]n1 +Cn1c(N)nnc1SCC(=O)NCc1ccccc1 +O=C(NCCc1ccccc1)C1CCCN(C(=O)NC2CC2)C1 +COc1cccc(CNc2ccccc2C(=O)N(C)C)c1 +Nc1c(NCc2ccccc2)ncnc1NCc1ccccc1Cl +CCCCS(=O)(=O)NCC1CCN(C)c2ccccc21 +COc1ccc(C(C)=O)c(OCc2cc(F)cc3cccnc23)c1 +O=C1CCC(C(=O)Nc2ccc(OCc3ccccc3)cc2)N1 +NC(=O)NCCCCC(=O)Nc1cc(Cl)ccc1-n1cccn1 +COC(=O)c1cc(-c2ccc(F)cc2)nc2c1c(=O)n(C)c(=O)n2C +CCCNC(=O)CNC(=O)c1cc(C)nc2c1cnn2C(C)C +CC(C)c1nnc(-c2coc(S(=O)(=O)N3CCCC3)c2)o1 +CC(C)(C)Cc1cc(NC(=O)C2(C)Oc3ccccc3NC2=O)on1 +CC(NC(=O)Nc1ccc(Cl)cc1)c1ccccn1 +Cc1ccccc1-n1nnc(CO)c1-c1ccncc1 +C=CCN1C(=O)CCCC12CCCN(C(=O)c1ccccn1)C2 +CN1C(=O)CCc2cc(C(O)C3CCCC3)ccc21 +O=C(NCC1CCN(C(=O)Nc2ccc(F)cc2)CC1)C1CCC1 +CC1OCCN(Cc2ccn(Cc3ccccc3)c2)C1C +CCCNC(=O)CNc1ccc(NC(=O)CC)cc1 +Nc1nc(-c2ccccc2F)ncc1C(=O)Nc1cccnc1 +CCCCN(C)S(=O)(=O)N(C)c1ccccc1F +Cc1ccc(C(=O)NCC(C)C)cc1NC(=O)c1ccco1 +Cc1cccc(NC(=O)CCc2nc(-c3ccccn3)no2)c1C +CCCc1n[nH]c(C2CN(CC(F)(F)F)CCO2)n1 +Cc1noc2ncnc(NC3CCN(C(=O)N4CCOCC4)CC3)c12 +Cc1cn2nc(NCC3CCc4nnc(C(C)C)n4C3)sc2n1 +CCC(C)n1nccc1NS(=O)(=O)c1cccc(F)c1F +COCCOc1ccc(CNc2ncnc3c2cnn3C)cn1 +CNC(=O)c1ccc(C=C(C)c2nc3sccc3c(=O)[nH]2)cc1 +COc1ccccc1Oc1ncccc1CNc1nc(C)cc(C)n1 +COc1ccccc1C1NCCc2ccc(OC)c(F)c21 +COCCCNC(=O)C(C)S(=O)(=O)c1ccc(O)cc1 +CNC(=O)C1CCCCN1C(=O)c1cccc(N)c1 +Cc1cc(C)c(NC(=O)CN(C)C(=O)Cn2cnnn2)c(C)c1 +Cc1cc(C)c2nc(-c3cc(N)cc(N)c3)sc2c1 +COc1cc(C(=O)N2CCN(Cc3ccc(C#N)o3)CC2)ccc1C +Nc1ccc(C(=O)Nc2cccc(S(=O)(=O)CCO)c2)cc1 +O=C(COC(=O)c1cc(Br)c[nH]1)Nc1ccccc1 +COc1ccc(C(C)=O)cc1COC(=O)c1ccc2ccccc2n1 +CC(=O)Nc1cc(NCC2CCC=CO2)ccc1F +CCOc1ccc(Cl)cc1S(=O)(=O)N1CCN(CCO)CC1 +CN(C)c1ccccc1N(C)C(=O)c1ncn(-c2ccccc2)n1 +Cc1ccccc1NC(=O)NCCCn1c(C)nc2ccccc21 +CCc1ccc(C(=O)Nc2cccc(OCCC(N)=O)c2)cc1 +CCC1(CNC(=O)NCCCc2nc(C)no2)CCCC1 +CCn1cnnc1CNC(=O)CSc1cc(Cl)ccc1Cl +COc1cc2c(cc1OC)C(C(C)C)N(C(=O)COC(C)=O)CC2 +O=C(Cn1c(C2CC2)nc2ccccc21)N1CCCC1c1ccncc1 +CNC(=O)c1cccc(CN(C)c2ccccc2N(C)C)c1 +CCOCCOCC(=O)Nc1cc(Br)ccc1C +COc1ccccc1-c1nccn1CCCn1cncn1 +CCCn1nc(-c2ccc(CC)cc2)cc(N)c1=O +O=C(NCCc1ccc(F)cc1)C1CSc2nccc(=O)n2C1 +Cc1ccc2cccc(NC(=O)c3cccc(Cl)c3)c2n1 +COc1ccc2c(c1)CC(NS(=O)(=O)Cc1ccccc1)CO2 +O=C(Nc1ccc2nccnc2c1)c1cc(F)c(F)cc1Cl +Cn1cc(CCNC(=O)c2nc(S(C)(=O)=O)n3ccccc23)cn1 +CNC(=O)C1Cn2ccnc2C2(CCN(S(C)(=O)=O)CC2)O1 +CN(C)C(=O)c1cccc(COc2ccccc2OCCO)c1 +Cc1nccnc1N1CCCC(N(C)C(=O)OC(C)(C)C)C1 +CC(=O)Nc1ccc(SC(C)C(=O)Nc2cccc(CO)c2)cc1 +CC(C)(C)NC(=O)CN(c1ccccc1F)S(C)(=O)=O +COc1ccc(NC(=O)c2cc(C)nn2-c2ccccc2)cc1 +O=C(c1ccco1)N1CCCC1c1nc(-c2ccccc2)n[nH]1 +CCN(CC(F)(F)F)C(=O)c1ccc(OC)c(OC)c1 +CCOC(=O)c1coc(N2CCCC3(CC2)CN(C)C(=O)O3)n1 +CC(C)OCCCNC(=O)Cc1ccc2c(c1)CCCC2 +O=C(Nc1cccc(OC(F)F)c1)N1CCOCC1C1CC1 +COc1ccc(CNC(=O)c2cccc3ncccc23)cc1O +C=CCNC(=O)N1CCc2nc(NC(=O)c3ccoc3)sc2C1 +Cc1cc(NCc2cccc(OCCCC#N)c2)c2ncccc2c1 +COc1ccc(-n2nnnc2-c2ccc(N)cc2)cc1 +CN(CC(C)(C)O)C(=O)CCCc1cc(F)ccc1F +O=C(CC1COCCN1C(=O)CCc1cscn1)c1ccccc1 +COc1ccc(NS(=O)(=O)c2cccc(C#N)c2)c(C)c1 +Cc1cc(C(=O)N(C)Cc2csc(C)n2)[nH]n1 +Cc1csc(CNc2ccc(C)c(C(=O)N(C)C)c2)n1 +CCN(CCNC(=O)c1cc(C)oc1C)c1cccc(C)c1 +CC(C)Nc1cc(N2CCC(CO)CC2)ncn1 +CN(Cc1cccs1)C(=O)CCn1ncc2ccc(Cl)cc21 +COC(=O)C1CCN(C(=O)c2cccc(-c3ccoc3)c2)CC1 +Nc1ccc(-c2csc3nnc(-c4ccccn4)n23)cc1 +COC(=O)CSc1ncn(S(=O)(=O)c2ccc(C)cc2)n1 +Cc1nc(-c2c[nH]c(C(=O)Nc3cnc(C(C)(C)C)nc3)c2)cs1 +CCC(CC)NC(=O)COc1ccc(C#N)cc1OC +O=C(COc1ccccc1)N(Cc1ccc2[nH]ccc2c1)C1CC1 +O=C(NC1CCCCC1)c1cc(-n2ccnc2)ccc1F +CC(C)CSc1ccc(S(=O)(=O)N2CCCC2)cn1 +CCNC(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CCC(C)C(=O)Cn1cc(-c2ccc(C)cc2)cn1 +CC(=O)N1CCCC1C(=O)Nc1ccc(Nc2ccccc2)nc1 +O=C(CCn1nnc(-c2ccccc2)n1)NCc1ccccc1Cl +O=C(c1ccc(OCC2CC2)nc1)N1CCOCC1C1CC1 +Cc1ccc(S(=O)(=O)N(C)c2ccccc2C(N)=O)c(C)c1 +CCCCn1c(C(C)NC(=O)CC)nc2ccccc21 +COC(=O)C(C)CNC(=O)Nc1c(C)cccc1C +COc1ccc(CNC(=O)c2cc3ccoc3cn2)cc1OC +CC1CC(C)CN(C(=O)NCc2ccc(S(N)(=O)=O)cc2)C1 +CC(COc1ccccc1)OC(=O)c1ccc2nncn2c1 +COc1cccc(CNC(=O)C2Cc3ccccc3CN2C(C)=O)c1 +O=C(NCCC1COc2ccccc2O1)c1ccc(-c2ccc[nH]2)nc1 +NC(=O)c1c(F)cccc1-c1ccnc2[nH]ccc12 +Nc1ncccc1-c1nc(-c2ccccc2OC(F)F)no1 +CC(C)n1cnnc1S(=O)(=O)C(C)c1ncc(C(C)(C)C)o1 +COCCCNC(=O)c1snc(-c2ccccc2)c1N +CNC(=O)Nc1ccc(Oc2cccc(F)c2)cc1 +CC(C)OCc1ccc(CNC(=O)c2ccc(=O)[nH]c2)cc1 +Cc1nc(CC(=O)N2CCCC2c2c(C)noc2C)cs1 +CC(C)n1c(C2CC(=O)N(c3cccc(F)c3)C2)nc2ccccc21 +N#CCOc1cccc(CNC(=O)c2ccc(-n3ccnn3)cc2)c1 +CCOc1c(N2CCN(c3cccc(C)c3)C(C)C2)c(=O)c1=O +CN(Cc1cccc(F)c1)C(=O)CCc1ccccc1O +CC(=O)N1CCC(C(=O)Nc2nc3ccccc3[nH]2)CC1 +CC(C)Nc1ncnc(Nc2ccc(C(N)=O)cc2)c1N +O=C(NCCn1cnnc1)c1cnc(-c2ccccc2)[nH]c1=O +O=c1onc(-c2ncccn2)n1Cc1ccn(-c2ccccc2)n1 +CN1CC(c2cccc(Br)c2)OCC1=O +Cc1nnc(N(C)Cc2ccccc2F)c(C#N)c1C +Cc1nc(-c2cc(C(=O)NCc3ccc(C#N)cc3)n(C)c2)cs1 +CCN(Cc1ccc2c(c1)OCCO2)C(=O)CN1CCOC(C)(C)C1 +CCOC(C)c1noc(CS(=O)(=O)c2cccc(Cl)c2)n1 +COc1cc(CNCCc2c(F)cccc2F)cc2c1OCO2 +CN1C(=O)CC(C(=O)NCCCOC2CCCC2)C1c1cccnc1 +CC(C)(C#N)C(=O)N1CCC(C(=O)NCCc2ccccc2F)CC1 +N#CCOc1cccc(CC(=O)N2CCC(C(N)=O)c3ccccc32)c1 +COC1CN(Cc2cccs2)C2CCCOC12 +CCCCn1c(=O)n(C)c(=O)c2c1nc(NCCO)n2CC +COC(=O)c1scc(C)c1NS(=O)(=O)c1cccc(Cl)c1 +Cc1nc(CNc2cccc(Br)c2)cs1 +O=S(=O)(N=c1ccc(CO)c[nH]1)c1ccc(Cl)cc1 +CCN(CCO)C(=O)c1sc(NC(=O)c2ccco2)cc1C +COc1ccc2nc(NC(=O)Cn3cnnc3C#N)sc2c1 +OC(CN(Cc1ccccc1)Cc1ccccc1)c1ccco1 +O=C(Cn1ccc2ccccc21)Nc1nc(C2CC2)cs1 +Cc1ccc(Nc2ccc(NC(=O)c3cccs3)cc2)nn1 +Cc1nnc(NCC(O)COc2ccc(F)cc2)c(C#N)c1C +Cc1cc(C)n(CC2CN(c3ncnc4ccccc34)CCO2)n1 +CCC(CC)c1nc2cc3c(cc2n1CCO)OCCO3 +Cc1nc(N2CCCC2)c2c(C)c(C(=O)N3CCOCC3)sc2n1 +N#CC1(Nc2cccc(N)c2)CCN(CCc2ccccc2)CC1 +COc1ccc(NC(=O)C2CC(=O)N(c3ccccc3F)C2)cn1 +Nc1nc(-c2cccnc2)ncc1C(=O)Nc1ccncc1 +CC(CO)CNC(=O)NCc1ccc(Cl)cc1 +CCc1cccc(C)c1NC(=O)NCc1cc(Cl)ccn1 +CCOc1ccc(C2NC(=O)NC3=C2C(=O)N(CC(C)C)C3)cc1 +Cc1nn(C)c(NS(=O)(=O)c2cccc(Cl)c2)c1C +Cc1ccsc1C(O)CNC(=O)c1cccc2ccccc12 +CCN(Cc1ccc(OC)cc1)C(=O)c1cccc(C)c1 +CNC(=O)CSc1ncnc2sc3c(c12)CCC3 +Cc1ccc(C(=O)N2CCC3C2CCC(=O)N3c2ccccc2)cn1 +COC(=O)CCN(C)S(=O)(=O)c1ccc(Cl)c(N)c1 +CCOc1ccccc1-c1nn(C(C)C(=O)N(C)C)cc1C +COC(=O)c1cccc(NS(=O)(=O)Cc2ccccc2)c1C +Cc1csc(-c2ccc(NC(=O)NCc3cnn(C)c3)cc2)n1 +COc1cc(CCC(=O)Nc2ccc(C)cn2)cc(OC)c1OC +COc1ccc(NC(=O)c2cc(C)n3nc(-c4ccco4)cc3n2)cc1 +Nc1nc2nc3c(c(C4CC=CCC4)c2c(=O)[nH]1)C(=O)CCC3 +CCn1nc(C)c(NC(=O)COc2ccc(Cl)cc2Cl)c1C +Cc1cccc(NC(=O)C2CCN(C(=O)c3ccccc3F)CC2)c1 +COc1ccc(N2CC(C(=O)N(C)C(C)C)CC2=O)cc1OC +Cc1n[nH]c(SCC(=O)N2CCN(c3ccccc3)CC2)n1 +COc1ccnc(NC(=O)c2cc(C3CC3)nc3onc(C)c23)c1 +COCCc1ccc(OS(=O)(=O)c2ccc(C#N)cc2)cc1 +CCOC(C)C(=O)Nc1ccccc1C(=O)N(CC)CC +Cc1cccc(OCc2ccc(C(=O)Nc3ccncc3)o2)c1 +Nn1c(SCc2ccc(F)cc2)nnc1-c1cccs1 +CC(NS(=O)(=O)c1ccc(N)cc1)c1ccccc1 +CN(C(=O)Cc1cn2ccsc2n1)c1cccc2ncccc12 +Cn1cc(CN2CCN(C(=O)Cc3cccs3)CC2)ccc1=O +CCC(=O)c1ccc(S(=O)(=O)Cc2ccc(C#N)cc2)cc1 +Cn1c(=O)n(C)c2cc(C(=O)Cc3ccccc3)ccc21 +CCNC(=O)C(C)Sc1nc(C)cc(-c2ccccc2)n1 +Cc1csc(C(C#N)C(=O)CCNC(=O)c2ccsc2)n1 +Cc1ccc(NC(=O)CN(C)S(=O)(=O)c2cccc(C#N)c2)nc1 +CCCCc1cn(C2CCN(C(=O)C3CCCO3)CC2)nn1 +O=C(NCc1ccncc1)c1c[nH]c2ccccc2c1=O +Cc1nc2ncccn2c1C(=O)N1CCC(C)(O)C(CC(C)C)C1 +O=C(NCc1cccs1)NCC1CCN(c2cnccn2)CC1 +O=C(OC1C(O)C(O)C(O)C(O)C1O)c1cccnc1 +CC(=O)N1CCN(Cc2cc(Br)c3c(c2)OCO3)CC1 +O=C(Nc1ccc2scnc2c1)c1cc2ccccc2oc1=O +COc1ccccc1OC(=O)c1cc(C(N)=O)cs1 +CC(=O)NCc1ccc(C(=O)N(C)Cc2ccsc2)cc1 +CC(Sc1ccc(Br)cc1)C(=O)N1CCOCC1 +COCCCNC(=O)NCC(C)(C)c1cccc(Cl)c1 +COCCN(CC(C)C)C(=O)c1nn(C)c(=O)c2ccccc12 +Cc1cc(C)cc(C(=O)NCc2cc(-c3ccco3)on2)c1 +CCOc1ccc(OCC)c(NC(=O)c2cccnc2)c1 +Cn1c(CO)nnc1C1CCCN(Cc2ccc(-c3cc[nH]n3)o2)C1 +CC(=O)NCc1ccc(-c2noc(-c3ccc(N(C)C)cc3)n2)s1 +O=C(NC1CC1)c1ccc2nc(CCc3ccccc3)oc2c1 +CC(=O)Nc1ccc(S(=O)(=O)NC(C)=O)cc1 +CCN(CC)C(=O)CN(C)S(=O)(=O)c1ccc(F)cc1 +O=C(NCCCN1CCCC1=O)NCc1ccsc1 +COCCN(C)S(=O)(=O)c1ccc(OC)c(N)c1 +Cn1ncc(Br)c1C(=O)n1cc(Br)cn1 +CCn1c(=O)n(-c2ccc(Cl)cc2)c(=O)c2sccc21 +CCCNC(=O)CNC(=O)Nc1ccc(Cl)c(Cl)c1 +Cc1ccc(S(=O)(=O)Cc2c[nH]c3ccccc23)cc1 +Cc1ncsc1CCNS(=O)(=O)NCc1ccccc1 +Cc1nc(COc2ccc3c(c2)CCCC3=O)no1 +CCN(Cc1cccc(F)c1)C(=O)NCc1ncn(C)n1 +CNC(=O)CNC(=O)NCCCc1ccc(Cl)c(Cl)c1 +COc1ccccc1-n1ncc2c(=O)[nH]c(C)nc21 +Cc1occc1C(=O)NCc1nc2ccccc2[nH]1 +CC(C)C(C)NC(=O)CN1C(=O)c2cccc3cccc1c23 +COc1ccc(C(O)CCC(=O)N2CCC(C)CC2)cc1F +COCCNC(=O)Cn1c(-c2ccccc2)ccc(C#N)c1=O +Cc1cc(C2CCCN2C(=O)Cc2c(C)nn(CC(C)C)c2C)on1 +CCc1ncc(C(=O)Nc2ccc(C(N)=O)cc2C)s1 +Cc1ccccc1CC(=O)NCc1ccc2c(c1)OCCO2 +O=C(NC1(c2ccc(Br)cc2)CC1)c1csnn1 +CCc1cc2c(nc(-c3cccnc3)n3nnnc23)s1 +CC(NC(=O)NCc1cccnc1-n1ccnc1)C1CCCO1 +CCSc1ccccc1C(=O)NCC#CCOc1ccc(C)nc1 +COc1cccc2c1cc(C(=O)NCCc1ccc(C)o1)n2C +COc1ccc(F)c(NC(=O)C(C)c2c(C)noc2C)c1 +C=CCn1c(CC#N)nc2cc(Br)ccc21 +Cc1cc2occ(CC(=O)Nc3cccn(C)c3=O)c2cc1C(C)C +CCC(C)C(=O)NC1CCN(c2ccc(F)cc2)CC1 +CCCn1ncc(C(=O)NCc2ncc3c(n2)CCC3)c1C +CCc1nnc(Cn2c(-c3ccccc3)noc2=O)o1 +Cc1cc(C(=O)Nc2ccc(C)c(N3CCCCC3=O)c2)c(C)o1 +Cc1c(C)n2c3c(=O)n(C)c(=O)n(C)c3nc2n1-c1ccccc1N +CC(Sc1ccc(-c2ccccc2)cc1)C(=O)N(C)CCC#N +CC(Sc1nccn1C)c1nc(-c2cccs2)no1 +OC(CN(Cc1cccnc1)CC1CCCO1)c1cccc(F)c1 +Cc1ccc(CCNC(=O)C2CCN(C(=O)C3CCCC3)CC2)s1 +Cc1cc(C)n2nc(C)c(C(=O)N3CCCC(C)CC3)c2n1 +CC(C(=O)N=c1[nH]ccn1Cc1ccccc1)n1cnc2ccccc21 +CCC(=O)Nc1ccc(NC(=O)NCc2ccnn2C)cc1 +COc1cc(NC(=O)C2CC2)ccc1S(N)(=O)=O +NC(=O)C1CCN(C(=O)c2ccc(-n3cccn3)cc2)CC1 +COCC(NC(=O)c1cc(C)n(C(C)(C)C)n1)C(N)=O +NC(=O)c1ccc(CN2CCN(C(=O)CC3C=CCC3)CC2)cc1 +COc1cccc(S(=O)(=O)N(CCc2cccs2)C2CC2)c1 +Cc1ccc2c(c1)c1nnc(SCCN3CCOCC3)nc1n2C +CCc1nc(CSc2nnc(NCC(C)C)s2)no1 +Cc1nnc(N2CC3COCC3(CNS(=O)(=O)C3CC3)C2)s1 +Cc1cc(C)n2nc(CN(C(=O)C(C)C)c3ccccc3)nc2n1 +O=C(Cn1cccnc1=O)Nc1ccc(Oc2ccccc2)cc1 +Cc1scc2nc(C(=O)NCc3cccs3)nc(N(C)C)c12 +COCc1nnc(NC(=O)Cc2csc(C)n2)s1 +Cc1ccc(CNS(=O)(=O)c2cnn(C)c2N)cc1 +Cc1cc(C)n(-c2ccc(C(=O)N(C)c3ncccc3C#N)cc2)n1 +COc1ccc(NC(=O)c2ccc(=O)n(C)c2)cc1OC +CN(C)C(=O)Cc1ccc(NC(=O)Nc2c(F)cccc2F)cc1 +Cc1ccc(CC(=O)Nc2ccccc2OCC(C)C)cn1 +NS(=O)(=O)Cc1ccc(NCc2cnccn2)cc1 +Cc1nn(C)c(C)c1NC(=O)CN1C(C)COCC1C +CC(C)NC(=O)Nc1ccc(C#CCCO)cc1F +Cc1cc(CSc2nnc(COc3ccc(Cl)cc3)o2)on1 +Cc1ccc(Br)c(S(=O)(=O)N(C)CC(O)C2CC2)c1 +CC(O)(CNC(=O)c1n[nH]c(=O)c2ccccc12)c1ccc(F)cc1 +O=C(CCC1CCCCC1)N1CCN(C(=O)C2CC3CCC2O3)CC1 +CCN(CCC(=O)OC)C(=O)c1cccc(OC)c1 +CS(=O)(=O)c1cccc(OS(=O)(=O)c2ccccc2F)c1 +Cc1ccc(NC(=O)C(C)Oc2cccc(N)c2)c(C)c1 +OCCc1sc2nccn2c1-c1cccs1 +C=CCNC(=O)NCc1ccccc1-n1ccnc1 +CC(C)C(=O)NCC1CN(Cc2ccccc2)CCO1 +COCn1nc(C#N)cc1-c1ccc(CC(C)C)cc1 +O=C(c1ccc[nH]1)N1CCCCC1Cn1cccn1 +COCCCNC(=O)CNc1cccc2ccccc12 +Cc1c(C(=O)N2CCOC(CCCC(C)C)C2)cnc2cc(=O)[nH]n12 +O=C1COc2ccc(COC(=O)C3CCCN3)cc2N1 +O=C(CCCn1cccc1)Nc1ccccc1Cl +O=C(Cc1noc2ccccc12)N(CC1CCCO1)c1ccncc1 +OC(CNc1ccc(Oc2ccccc2)cc1)c1ccncc1 +Cc1ccsc1C1C(C(N)=O)=C(N)Oc2[nH]c(=O)[nH]c(=O)c21 +CCCCCCNC(=O)Cn1c(=O)cnc2ccccc21 +CCN(C(=O)c1n[nH]c2ccccc12)C1CCCC1 +CC1(C)Cc2nc(Cc3ccncc3)sc2C(O)C1 +O=C(Nc1cccc(Cl)c1)N1CCN(c2cccc(O)c2)CC1 +O=C(COc1coc(CO)cc1=O)Nc1ccccc1Cl +COc1cc(OC)c(NC(=O)Nc2ccccn2)cc1F +Cn1cccc1CN(CCC#N)Cc1ccccn1 +N#CCCN(C(=O)COc1ccccn1)c1ccccc1 +Cc1cc(C)n(CC(=O)Nc2ccc(C(F)(F)F)cc2)n1 +CCCCNC(=O)Cn1nc2c(cc1=O)CCCC2 +C#CCOCC1CCCN(C(=O)Nc2cccc(OC)c2)C1 +Cc1cccc(C(C#N)N(C)C(=O)c2ccccc2F)c1 +CC(=O)NCC(=O)NC1(C(=O)NC2CCCCC2)CCCCC1 +COc1ccc(C)cc1NC(=O)C1(C)CC1(Cl)Cl +CC(C)CC(C)Oc1cc2c(cc1N)OCCO2 +CC(C)(C)OC(=O)NCC(O)c1ccc(C#N)cc1 +O=C(CCNC(=O)c1ccccc1)Nc1n[nH]c2cccc(F)c12 +NC(=O)C(c1ccccc1)N1CCOC(c2ccc(F)cc2)C1 +Cc1cccc(N(C)Cc2cc(=O)n3nc(C)sc3n2)c1 +CC(Sc1nncn1Cc1ccco1)C(=O)N(C)C +CCCC1CCCN(C(=O)c2ccc(-c3ccccn3)[nH]c2=O)CC1 +CC(=O)Nc1ccc(-c2nc3cc(C)ccc3n2C)cc1 +COc1ccc(-c2nc(NC(=O)c3cccn3C)sc2C)cc1 +COCCNc1nc(-c2csc(COC)n2)cs1 +CN(CC1(CO)CCC1)c1nccc(C2CCCC2)n1 +COc1ccccc1OCC(=O)NC1(C#N)CCCC1 +CCn1c(CCNC(=O)c2cc(Cl)ccc2F)nc2cccnc21 +CC(NC(=O)CSc1ncn[nH]1)c1ccc(Cl)c(Cl)c1 +Cc1nc(CNc2ccc(-c3cc[nH]n3)cc2)cs1 +Cc1ccc(-n2cnnn2)cc1NC(=O)Cc1noc2ccccc12 +Cc1cc(C(=O)CN2CCC(=O)CC2)ccc1OC(C)C +CC(Sc1cc(C#N)ccn1)C(=O)N(C)CC(=O)NC1CC1 +Nn1c(SCc2cccc3ccccc23)nncc1=O +CCn1nc(-c2ccc(OC(C)C)cc2)cc(C(C)=O)c1=O +CC(C)c1csc(NC(=O)c2ccc(C#N)cc2)n1 +CCCCC(Nc1cc(C)nc2ccnn12)c1cccnc1 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+CCOC(=O)CN(CC)S(=O)(=O)c1cccc(C)c1 +Cc1cnc2c(c1)nc(C)n2CCOc1cccc(N)c1 +CCN1CCN(C(=O)c2c(Br)cnn2CC)CC1 +Cc1ccc(C(C)NS(=O)(=O)c2ccc(F)c(F)c2F)o1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccsc1 +CC(C)(C)OC(=O)N1CCC(c2nnc3ccccn23)CC1 +Nc1ccc2ccnc(C(=O)NCCCN3CCOCC3)c2c1 +O=C(CSc1ccccn1)NCC1CCCCC1 +COc1ncnc2c1CCN(Cc1csc(C)n1)CC2 +Cc1nc(C(C)(C)NC(=O)NCc2nnc3ccccn23)sc1C +CCc1nc2n(n1)CCCC2NC(=O)NCc1csc(N(C)C)n1 +Fc1ccc(OCC2CCCO2)c(NCc2cn3cccnc3n2)c1 +O=C(c1cccnc1N1CCCC1)N1CCC(Oc2ccccc2)C1 +CC(C)CCN(C)C(=O)c1ccc(-n2ccc(C(F)(F)F)n2)cc1 +CCOC(=O)c1nsc(C(=O)NC(C)(C)C)c1N +CC(C)C(=O)N1CCC(Nc2ncnc3ccsc23)CC1 +COCCOCC(=O)N1CCCc2c(C(N)=O)cccc21 +CCOCC1CCCN(C(=O)Nc2ccc3c(c2)CCC3)C1 +CCc1cccc(C)c1NC(=O)COC(=O)c1nccc2ccccc12 +CC1=C(C(=O)OC2CCCC2)C(c2ccc3c(c2)OCO3)NC(=O)N1 +CC(=O)c1ccc(OC(=O)Cc2ccccc2)cc1 +COCC(O)CN(C)C(=O)Nc1cccc(-c2nnc3n2CCC3)c1 +CCn1nc(C(=O)NCCc2cccc(OC)c2)ccc1=O +Cc1cc(NC(=O)N2CCN(c3ncccn3)CC2)no1 +COCc1nc(C(=O)NC2(c3ccccc3)CCCC2)cs1 +CC(OC(=O)c1ccc(-n2cnnn2)cc1)C(=O)NC1CC1 +CC(C)(C)C(=O)CSc1ncnc2c1cnn2-c1ccccc1 +CCn1cnnc1-c1cccc(NCc2nc3ccccc3n2CC)c1 +CCN1C(=O)C(C)(C(=O)NC2CCCCC2)Oc2cccnc21 +CCn1ncc(-c2cc(C(F)F)nc(NC)n2)c1C +CC(CCc1ccccc1)NC(=O)C1CC(=O)N(CC(F)(F)F)C1 +COCC(NC(=O)c1ccc(Oc2cccc(Cl)c2)cc1)C(N)=O +CCOC(=O)N1CCN(S(=O)(=O)Nc2ccccc2CC)CC1 +COc1cc2nc(-c3cccs3)n(CCCO)c2cc1OC +CCN(C(=O)Nc1ccc2c(c1)OCO2)C(C)C(C)C +Cc1[nH]nc(O)c1CCOC(=O)c1ccc(Br)cc1 +O=C(COc1cccnc1)NCC#CCOc1ccccc1F +CCC(=O)N1CCC(c2nc3ccccc3[nH]2)CC1 +Cc1ccc(CN2CCN(C(=O)CCC(C)C)CC2)s1 +CN1C(=O)Cc2cc(-c3cn4c(N)csc4n3)ccc21 +CC(=O)N(C)Cc1cccc(NC(=O)NC(C)CCCO)c1 +Cc1c(CNC(=O)Nc2cnn(CC(F)F)c2)cnn1C +COc1ccc(CNC(=O)c2cn(C)nc2C)c(F)c1F +CCOc1cc(CNC(=O)c2ccccc2F)ccc1OC(F)F +CC(=O)N1CCN(CC(=O)NCCc2ccc3c(c2)OCCO3)CC1 +CCOc1cccc(C(C)NS(=O)(=O)CC)c1 +O=C(NCCn1nc(-c2ccccc2)ccc1=O)c1ccccn1 +CCCn1nc(-c2ccc(F)cc2)cc(C#N)c1=O +CCC(=O)C1(NC(=O)Cc2csc(CC)n2)CCCCC1 +Nc1ccc(C(=O)NC2CCC(=O)NC2)c(Cl)c1 +CN(CC(=O)OCC1CC=CCC1)C(=O)c1cccs1 +CC1CCCCN1C(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1 +CC(C)CC(=O)Nc1sc2c(c1C(N)=O)CCC(C)C2 +CC(C)N(CCC#N)S(=O)(=O)c1ccc(F)cc1F +Cc1ccc(C)c(OC(C)C(=O)Nc2cccc(C(N)=O)c2)c1 +Cc1ccc(C(C)NC(=O)c2sc(C)nc2C)cc1 +CCCOc1ccc(N2CCN(C(=O)c3ccccc3)CC2)nn1 +COc1ccc(C(C)=O)cc1Cn1ccccc1=O +CN(C(=O)c1c(F)cccc1Cl)C(C#N)c1cccnc1 +COCc1noc(-c2ccc(CNC(N)=O)cc2)n1 +Cc1ccccc1S(=O)(=O)CCNC(=O)OCC(F)(F)F +COc1ccc(S(=O)(=O)N2CC(C)OCC2C)cc1C(N)=O +O=C(NCc1ccccc1Oc1ccccc1)c1csnn1 +CCc1ccc(CNc2nonc2C(=O)OC)cc1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)CNC(=O)OC(C)(C)C +O=C(c1ccsc1)N1CCOC2(CCCC2)C1 +COc1cc2c(cc1OC)CCN(C(=O)CCc1ccccc1)CC2 +CC(C)(C)C1CCCCC1NC(=O)NCCCc1n[nH]c(N)c1C#N +Nc1ccccc1CCC(=O)NCc1ccc2c(c1)OCO2 +CC1CCCCN1C(=O)Cn1ncc2c1-c1ccccc1OC2 +COc1ncccc1CNC(=O)c1csc(-c2ccsc2)n1 +CCC(C)NC(=O)C(C)NC(=O)NCc1ncc(C)c(OC)c1C +CC(Cn1cc(Cl)cn1)C(=O)NCC(=O)C(C)(C)C +Cc1ccc(Oc2ccc(NC(=O)c3cc[nH]c(=O)c3)cn2)cc1C +CC(N)C(=O)OCc1ccc2c(c1)nc(C1CC1)n2C +CCOc1ccccc1CNC(=O)NCc1csc(CC)n1 +O=C(Nc1ccc2c(c1)OCO2)c1cnn2c1OCCC2 +CC1CCCC(OCC(=O)N(C)CC(=O)NCC(F)(F)F)C1 +Cc1occc1-c1nnc(SC(C)C(=O)NC2CCCCC2C)o1 +COc1cccc(C(C#N)CC(=O)Nc2c(C)cccc2C)c1 +CC(C(=O)N(C)Cc1ccccc1)S(=O)(=O)c1ccccc1 +Cc1ccc(C(=O)Nc2ccc(S(N)(=O)=O)c(C)c2)cc1C +CC(C)c1nnc(NC(=O)c2cc3ccccc3[nH]2)s1 +Cc1ccc(-c2nnc(COc3c(CO)cc(F)cc3CO)o2)cc1 +Cc1cc(CNC(=O)c2ccc(N3CCOCC3)c(F)c2)c(C)o1 +COc1ccnc(NC(=O)C2(Cc3ccccc3)CCC2)c1 +C=CCN(CC=C)C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +CC(=O)c1cccc(OC(=O)c2cc(CC(C)C)n[nH]2)c1 +Cc1ccc(NC(=O)COc2nc(C)nc3ccccc23)cc1 +CCc1csc(CNC(=O)c2csc(C)n2)n1 +Cc1ccc(C(C)NS(=O)(=O)c2cccs2)s1 +COc1ccccc1NS(=O)(=O)c1c(C)nn(C)c1C +CC(C)(C)OC(=O)N1CCC(C(=O)N2CCc3cc(F)ccc3C2)C1 +CCOC(=O)c1c(N)n(Cc2ccccn2)c2nc3ccccc3nc12 +COCC(C)NC(=O)NC(C)COc1cccc(C)c1 +Cc1cc(NC(=O)CCN2C(=O)COc3ccccc32)ccn1 +CC(CNC(=O)NC(C1CC1)C1CC1)N1CCOCC1 +CC1CN(C(C)c2nc(C3CC3)no2)c2ccccc21 +Cc1n[nH]c(C(=O)NCC(=O)NCC(F)(F)F)c1Br +Cc1cc(Cl)ccc1NC(=O)c1cnc(N2CCOCC2)nc1 +NC(=O)CSc1nnc(SCc2ccc(F)c(F)c2)s1 +CC(C)N(C(=O)Cn1nc(-c2ccco2)oc1=O)c1ccccc1 +COCCNCc1ccnc(-c2ccc(Br)cc2)n1 +Cc1c(N(C)Cc2ccccc2)ccc2nc(N)nn12 +CC(Oc1ccccc1)C(=O)Nc1cc(C#N)cn1C(C)(C)C +Cc1cccc(NC(=O)CNC(=O)COC(=O)c2ccco2)c1C +Cc1ccc(N2CCCN(C(=O)C3CC=CCC3)CC2)nn1 +Cn1cnc(CNC(=O)c2cc3c(Br)cccc3[nH]2)n1 +CCS(=O)(=O)NCC#CCOc1ccc(F)cc1F +CCOC(=O)c1sc(-c2ccc(NC(=O)C3CC3)cc2)nc1C +CCC(=O)N1CCCCC1C(=O)NCc1cc(C)oc1C +Cc1cn(C)nc1C(=O)Nc1nc2cc3c(cc2s1)OCO3 +O=C(Nc1nc(C(=O)NCCc2ccccc2)co1)c1ccccc1 +CCCCC(=O)NCC(c1ccc(Cl)cc1)N1CCOCC1 +Cc1nnnn1-c1cccc(NC(=O)N(C2CC2)C(C)C2CC2)c1 +CC(C)(CNC(=O)c1cc(F)ccc1F)N1CCOCC1 +Cc1ccccc1OCCN(C)C(=O)c1cccc(C#N)c1 +Cn1ccnc1C(NC(=O)N1CCOCC1)c1ccccc1F +COc1ccc(CNC(=O)Nc2ccc3c(c2)CCC3)cc1F +O=C1CCCN1Cc1ccccc1CNc1nc2ccccc2o1 +CN(CC(N)=O)C(=O)CN(C)S(=O)(=O)c1cccs1 +Fc1ccc(-n2ncc3c(NCc4ccccn4)ncnc32)cc1 +NC(=O)C1CCN(c2ccc(C(=O)N3CCc4ccccc43)cn2)C1 +CC(C)Nc1ncnc2c1CCN(C(=O)Cc1ccsc1)CC2 +O=C(Nc1ccc2nc(N3CCCC3)sc2c1)c1ccoc1 +CC(=O)N1CCc2ccc(NS(C)(=O)=O)cc2C1 +COc1ccccc1CNC(=O)c1cccc(-n2cccc2)c1 +COc1cccc(-c2cc(CN3Cc4ncccc4C3=O)no2)c1 +COc1ccc(C)c(NC(=O)NCCOCCO)c1 +COCCOc1ccccc1C(=O)NC1CCCc2occc21 +CSc1ccc(C2NC(=O)Nc3c2c(=O)n(C)c(=O)n3C)cc1 +CCc1nccn1S(=O)(=O)c1ccc(OC)c(C(C)(C)C)c1 +CC1COCCN1C(=O)c1cccc(NC(=O)c2cccs2)c1 +COCc1cccc(NC(=O)c2ccc(N3CCOCC3)cc2)c1 +O=C(CSc1nc2ccccc2n1-c1ccccc1)N1CCCC1 +CCN(Cc1cccs1)C(=O)CNC(=O)c1cccc(F)c1 +CCOC(=O)CN(CC)C(=O)c1ccc(Cl)cc1 +COc1ccc(Br)c(C(=O)N2CCC(OC)CC2)c1 +CC(Sc1ccccc1F)C(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +COCCN(C)C(=O)Nc1ccc(C)c(Cl)c1 +CCN(CC)c1ccc(C(=O)N2CCN(c3ccccc3)CC2)cc1 +CCOc1cccnc1C(=O)N1CCN(c2ncccc2Cl)CC1 +CN(Cc1ccccc1)Cc1cc(=O)[nH]c(-c2ccccc2)n1 +O=C(NCC1CC2CCC1C2)c1ccc(Cn2cncn2)cc1 +Cc1cc(NC(=O)C2CC2C)n(-c2ccccc2)n1 +CCC1CCCN(C(=O)c2ccc(-c3cscn3)cc2)C1 +CCCCS(=O)(=O)NCC(=O)N1CCCC(c2cn[nH]c2)C1 +O=C(CN1CCOCC1)N1CC=C(c2c[nH]c3ccccc23)CC1 +CCCNC(=O)CNC(=O)Nc1cccc(-c2nnc3n2CCC3)c1 +COC(=O)N1CCC(NC(=O)c2ccc(O)c(Cl)c2)CC1 +Cc1noc(C)c1C(C)C(=O)N(C)Cc1nc2ccccc2o1 +CC(NC(=O)CC(NC(N)=O)c1cccs1)c1ccc(F)cc1 +Cc1ccc(SCCCC(=O)N2CC(=O)Nc3ccccc32)cc1 +CN(C)c1ccc(C(=O)NCCc2ccco2)cc1F +CN(Cc1cccc(Cl)c1Cl)S(=O)(=O)c1cnn(C)c1 +COCCCN(C)C(=O)Nc1ccc(Cl)cc1Cl +CC1CS(=O)(=O)N(c2cccc(Br)c2)C1=O +CN(C)C(=O)N1CCc2onc(COc3cccnc3)c2C1 +COc1ccccc1C(=O)NCC(=O)NC1CCCc2ccccc21 +CC1(C)COc2c(Br)cc(N)cc2NC1=O +O=C(c1ccsc1)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +COCCCNC(=O)C1CCN(c2nnc(-n3cccc3)s2)CC1 +CC1(C)COCCN1C(=O)c1ccc(OCC(F)(F)F)nc1 +Cc1cc(NC(=O)N(C)Cc2cccc(C#N)c2)ccc1-n1cnnn1 +N#Cc1cc(N)ccc1NCCc1ccc(Cl)cc1 +COc1ccc(C)cc1NC(=O)COC(=O)c1ccccc1N +Cc1cncc(C(=O)OC(C)c2ccc(-n3cncn3)cc2)c1 +CC1(C)CN(C(=O)COc2ccccc2Cl)CCO1 +Cc1c(Br)cccc1NC(=O)C1CC2CCC1O2 +Cc1ncc(CNC(=O)C2(c3ccc(F)cc3)CCC2)s1 +CC(NC(=O)N(Cc1ccccc1)CC1CCCO1)c1ccncc1 +CC(C)n1cnnc1SCC(=O)NCc1ccc(C(C)(C)C)cc1 +Cc1ccc(S(=O)(=O)Nc2cccnc2)c(C)c1C +CC(C)c1nnc2sc(CCCc3cn[nH]c3)nn12 +CCC(C)(C)C(=O)Nc1ccc(OCC(=O)N(C)C)cc1 +Cc1cc(-c2csc(Nc3ccccn3)n2)c(C)n1C +CCNC(=O)Nc1ccc(-c2cc(C(N)=O)ccc2C)cc1 +COC(=O)c1sc(N2CCCCC2)nc1N1CCCC1=O +CCOCC1CCCN(S(=O)(=O)c2ccc(C#N)c(Cl)c2)C1 +Cc1cc(C(=O)N2CCC(OCc3ccccc3C)CC2)no1 +Cc1oc(-c2ccco2)nc1CC(=O)Nc1cc(F)c(F)c(F)c1 +CC(C)c1ccc(NC(=O)CS(=O)(=O)c2ccc(O)cc2)cc1 +COc1ccccc1CNC(=O)c1cccc(NC(C)=O)c1 +COCCC1(O)CCN(C(=O)NCC2CCCCC2)CC1C +CC(CCc1ccc(OC(C)C)cc1)NC(=O)NC1CCC(O)CC1 +CS(=O)(=O)N(Cc1ccco1)Cc1ccccc1Cl +COc1ccccc1NC(=O)Nc1cccc2cccnc12 +CCOc1ncccc1CN(C)C(=O)c1ccoc1 +Cc1noc(C)c1CCCNC(=O)C1CCN(C(=O)C2CC2)CC1 +Cc1nn(C)c(C)c1CCc1nc(C2CC2)nn1-c1ccccc1 +O=C(NC1CC1)c1ccc(S(=O)(=O)NCc2ccncc2)cc1 +CC(=O)c1ccc(NC(=O)N(CC(C)O)C(C)C)cc1C +CCOC(=O)c1ccccc1Cc1c(C#N)ncnc1C(F)(F)F +O=C(Nc1ccc(O)cc1)c1ccc(-n2cnc3ccccc32)nc1 +Cc1noc(C)c1CNC(=O)N1CCCC(NS(C)(=O)=O)C1 +CCNC(=O)NC1(C(=O)N(C)Cc2ccoc2C)CCCC1 +C=CCCS(=O)(=O)Nc1ccn(Cc2cccc3cccnc23)n1 +Cn1cc(C(=O)NCc2ccccc2Cl)c(C(C)(C)C)n1 +CCOc1ccc(-c2nnc(NCc3ccn(C)c3)o2)cc1 +CCc1cnc(C(C)NC(=O)c2cc(OC)c(OC)cc2C)s1 +COc1ccccc1Oc1ccc(NC(C)c2nc(C)no2)cc1 +O=C(Nc1ccccc1N1CCCC1=O)NC1CCCCC1 +CC(C)CC(NC(=O)C(C)NC(N)=O)c1cccs1 +COCCCN(C)C(=O)c1[nH]c2c(c1C)C(=O)CCC2 +Cc1cccc(-c2nc(CN3CCCC3=O)no2)c1 +C#Cc1cccc(NCC(=O)Nc2cccc(C)c2)c1 +CC(C)(C)Cc1nnc(NC(=O)c2ccc3c(c2)OCO3)s1 +CC1Cc2ccccc2N1C(=O)c1cccc(Cl)c1N +CS(=O)(=O)N1CCCC(Cc2nccs2)C1 +Cc1cc(C)c(NC(=O)C2CC2c2ccc(F)cc2)c(C)n1 +Cc1ncsc1CCOC(=O)c1ccc2c(c1)NC(=O)CO2 +COC(=O)C1=C(C(C)C)NC(=O)NC1c1ccccc1F +CC(C)c1noc(CCCC(=O)Oc2ccc3ccc(=O)oc3c2)n1 +CC(=O)NC(CC(=O)NCc1ccccc1C)c1ccccc1 +COc1ccc(CNC(=O)COC(=O)c2[nH]nc3ccccc23)cc1 +COc1ccc2cc(CN(C)C(=O)c3ccsc3)ccc2c1 +CNC(=O)C1CCCCN1C(=O)c1cc(-c2ccc(C)cc2)n[nH]1 +CCCCC(=O)N1CCN(c2cc(-n3ccc(C)n3)ncn2)CC1 +COc1ccc2c(c1)ncn2-c1ncccc1C#N +CCOc1ccc(S(=O)(=O)N2CCN(C(=O)CC)CC2)cc1 +Cc1cc(NC(=O)CNC(=O)OC(C)(C)C)no1 +NC(=O)c1ccc(Cl)c(NC(=O)Cc2cccc3ccccc23)c1 +COCc1cccc(CNS(=O)(=O)c2ccc(=O)[nH]c2)c1 +Cc1ncc(CNS(=O)(=O)c2ccccc2)s1 +CCCC1CCC(NC(=O)Nc2nnc(C)s2)CC1 +O=C(NCc1nc2ccccc2[nH]1)C1COc2ccc(F)cc2C1 +CCOC(=O)c1ccccc1NC(=O)c1cccc(N)c1C +CC1(C)CN(CCC(=O)N2CCN(c3ncccn3)CC2)CCO1 +CCCn1c(=O)[nH]c2cc(-c3noc(-c4ccsc4)n3)ccc21 +CN(C)c1ncc2c(n1)CN(C(=O)NCc1ccccc1)CC2 +Cc1ccc(OCCN(C)C(=O)c2cnc3n(c2=O)CCS3)cc1 +CCOc1ccc(-c2c(C#N)c(N)nc3sc(C#N)c(N)c23)cc1 +CC(C)=CCN1C(=O)C2CCC1CN(C(=O)c1cc(C)n[nH]1)C2 +CCOCc1ccccc1NCc1nnc(CC)o1 +N#CC(C(=O)c1cccc(Br)c1)c1ccccn1 +CN(C)C(=O)CCCn1ccc(NC(=O)NC2CCC(C)(C)CC2)n1 +CCOC(=O)Cn1c(CCNC(C)=O)nc2ccccc21 +O=C(Cn1ccnc1)Nc1ccnn1Cc1cccc(Cl)c1 +CC(NC(=O)c1cccs1)C(=O)Nc1ccc(F)c(F)c1 +CC1CC1COC(=O)c1ccc(-n2cncn2)cc1 +CC(NC(=O)c1ccccc1Cl)c1nc2ccccc2[nH]1 +CNC(=O)c1ccc(NC(=O)N(C)Cc2ccccc2C)cc1 +Cc1cc(C2CN(C(=O)Cc3ccon3)CCO2)ccc1F +Cc1nn(C)c(C)c1CC(=O)NC1CCCNC1=O +CCNC(=O)CNC(=O)NC(C)c1cc2ccccc2o1 +N#Cc1cccc(-c2cn3c(n2)N(C(=O)Cc2cccnc2)CCC3)c1 +Nc1cccc2c(-c3cn[nH]c3-c3ccccc3)n[nH]c12 +CNC(=O)CSc1nnc(SCc2ccc(OC)cc2)s1 +CC(=O)Nc1cccc(CNC(=O)CCc2c(C)nc(C)[nH]c2=O)c1 +Cc1ccc(OCCCc2nc(CO)cs2)cc1 +C=CCNC(=O)CCC(O)c1ccc(Cl)c(N)c1 +CC(=O)N1CCN(C(=O)c2ccc(-c3ccccc3)cc2)CC1 +O=C(Nc1cccc(C(=O)N2CCOCC2)c1)c1c(F)cccc1F +O=C(NC1CCN(C(=O)c2ccco2)CC1)c1cc2ccoc2s1 +O=C(Nc1cccc(CS(=O)c2ccccc2)c1)c1ccc[nH]1 +CCC1CCC(c2nc3sc(C(=O)NC)c(C)c3c(=O)[nH]2)CC1 +Cc1cccc(CC(=O)Nc2nc3cc4c(cc3s2)OCCO4)c1 +COC(=O)c1ccc(NC(=O)Cn2cc(-c3ccccc3)cn2)cc1 +C=CCNC(=O)Nc1nnc(-c2ccc(F)cc2)o1 +CN(C(=O)CCCc1c[nH]c2ccccc12)c1ccc(Cl)cn1 +COC(=O)C(C)(NC(=O)C1CN(Cc2ccccc2)CCO1)C1CC1 +COc1ccc(SCC(=O)Nc2ccc(F)c(F)c2)cc1 +COc1ccc(NC(=O)NC(C)c2c(C)nn(C)c2C)c(OC)c1 +CN(Cc1ccco1)C(=O)C1CCCN(c2ncccn2)C1 +CCn1c(C)cc(C)c(S(=O)(=O)c2ccccc2C)c1=O +CC1Cc2ccccc2N1C(=O)CNC(=O)c1ccc(C#N)cc1 +CN(C)c1ccc(C#CCNC(=O)c2ccc(C#N)cc2)cc1 +Cc1noc(CCCC(=O)N(C)C2C3CC4CC(C3)CC2C4)n1 +OCc1csc(N2CCOC(c3ccc(Cl)c(Cl)c3)C2)n1 +NC(=O)CN(C(=O)Cc1cccs1)c1ccccc1 +Cc1nccc(CNC(=O)CSc2ccc(Cl)cc2)n1 +CC(O)CC(CNC(=O)c1cc(F)cc(F)c1)c1ccccc1 +CN(CCc1ccc(F)cc1)C(=O)CNC(=O)c1cccs1 +O=C(c1ccc(NC2CC2)nc1)N1CCc2ccc(O)cc2C1 +Nc1cc(CCCNC(=O)NC2CCCC2)nn1-c1ccccc1 +CNC(=O)Cc1ccc(NCc2ccc(F)c(C)c2)cc1 +CC(c1ccccn1)N(C)C(=O)Nc1cc(C(F)(F)F)ccc1F +CCOC(=O)C1(NC(=O)c2cc(Cl)c[nH]2)CCCC1 +CC(C)N1CC(C(=O)NCc2nc3ccccc3[nH]2)CC1=O +COc1ccc(C(O)C(C)NC(=O)C(C)(C)c2ccccc2)cc1 +Cc1csc(CCNC(c2ccccc2)C2CC2)n1 +COc1cccc(-c2cc(-c3ccco3)nc(N)n2)c1 +COC(=O)c1ccc(NC(=O)Cc2ccc[nH]2)cc1Cl +CC1CC1CNS(=O)(=O)c1ccc2c(c1)CCC2 +CS(=O)c1ccc(CNC(=O)NCCCc2ccc(O)cc2)cc1 +Cc1cc(NC(=O)C2CN(S(C)(=O)=O)C2)sn1 +CCCn1c(-c2nonc2NC(C)=O)nc2ccccc21 +Cc1c(CCNC(=O)N(Cc2ccccc2F)C2CCC2)cnn1C +O=C(c1ccc(CSc2ccccc2)cc1)N1CCCC(O)C1 +CCOC(=O)CC(C)CNC(=O)c1cc2cc(F)ccc2oc1=O +COCc1cccc(NC(=O)N2CCc3ccc(OC)cc3C2)c1 +O=C(Nc1ccccc1O)c1ccc(NC(=O)c2cccs2)cc1 +O=C(CCC1CCCN(C(=O)CCc2cccs2)C1)NC1CC1 +O=C(COc1ccc(N2CCCC2=O)cc1)Nc1cn[nH]c1 +CCOc1cccc(NC(=O)CSc2ccncc2)c1 +Cc1cccc2c(=O)n(CC(=O)NCCCCC(C)C)cnc12 +COC(=O)c1sc(NC(=O)c2ccnn2C)nc1C1CC1 +O=C(Cn1nnc(-c2ccccc2)n1)Nc1ccc(Cl)cc1 +CCc1cnc(CCNC(=O)CC2OCCc3ccccc32)s1 +CCC(=O)NC1CC1c1ccccc1C(F)(F)F +CCCCc1nnc(NC(=O)c2cccnc2)s1 +N#Cc1ccccc1CSc1nccn1C1CC1 +CCc1noc(CC)c1CC(=O)NC1(C)Cc2ccccc2C1 +CC(c1ccccc1F)N(C(=O)NCCC(=O)N(C)C)C1CC1 +COc1cccc(C(=O)CC2(O)C(=O)N(C(C)C)c3ccccc32)c1 +CC1(C)Cc2c(sc(NC(=O)NCc3ccncc3)c2C#N)CO1 +Cc1cc(C(=O)Nc2ccc(Oc3ncccn3)cc2)c(C)n1C1CC1 +CCOc1c(Cl)cc(CNC(=O)NCCO)cc1OC +CCNC(=O)CS(=O)(=O)c1ccc(Br)cc1 +Cc1cccc(CSc2ncc(CO)n2CC(N)=O)c1 +N#CC(C(=O)c1scnc1C1CC1)c1ccccn1 +N#Cc1cccc(S(=O)(=O)Nc2ccc3c(c2)CCN3)c1 +CC(C)(C)c1nnc(N2CCN(C(=O)c3nc[nH]n3)CC2)o1 +CCc1nc2n(n1)CCCC2NC(=O)COc1ccccc1C#N +O=C(CC1(Cn2cnnn2)CCCCC1)NCCc1ccco1 +Cc1c(N)ccc2nc(-c3ccc(Br)cc3)cn12 +COc1ccccc1C(NC(=O)Cc1cccs1)c1ccccn1 +Cc1cccc(-c2nccc(C3CCCN(C(=O)c4ccco4)C3)n2)c1 +CC(C)(C)Oc1cc(C(=O)OCC#N)c(N)cc1F +COc1ccc2oc(CNc3cccc(C(N)=O)c3C)cc2c1 +CC1CC(C)CN(C(=O)Cc2ccc(F)cc2F)C1 +N#Cc1cc(S(=O)(=O)NCC(F)(F)F)ccc1F +O=C(COc1ccc(F)cc1)Nc1ccnn1C1CCCCC1 +Fc1cc(F)c2c(c1)CCNC2c1ccc2nn[nH]c2c1 +C#CCNC(=O)COc1ccc(C)cc1S(=O)(=O)N(C)C +COc1ccc2c(c1)OCC(C(=O)N1CCCOCC1)C2 +CC(C)(C)CCNC(=O)CSc1ncc2ccccn12 +O=C(NCc1cccnc1-n1cncn1)c1cc(=O)[nH]c2ccccc12 +Cn1cc(N2CCC(NC(=O)NCc3cc(F)cc(F)c3)C2=O)cn1 +O=C(CCC(=O)N1CCOCC1)Nc1ccc(-c2cc[nH]n2)cc1 +COC(=O)c1c(COC(=O)c2ccccn2)nc2ccccc2c1C +CC(=O)C(C)CN1C(=O)c2ccccc2S1(=O)=O +COCCCN(C)C(=O)c1ccccc1S(C)(=O)=O +CC(O)CN(c1ccccc1)S(=O)(=O)c1ccc(F)c(F)c1F +COCc1ccccc1CNC(=O)NCCC1=CCCCC1 +Cc1c(C#N)c(N)n(-c2ccc(Cl)c(F)c2)c1C +O=C(Nc1ccc2ncccc2c1)C1CC2CCC1O2 +CC(=O)c1sc2ncn(Cc3ccccc3)c(=O)c2c1C +Cc1ccccc1CC(=O)N1CCCC1c1ccc[nH]1 +CCC(C)Cn1c(N)c(NC(C)=O)c(=O)n(C)c1=O +COc1cccc(CNn2cnnc2)c1OCC(N)=O +CCC(NC(=O)NCCNC(=O)C1CCCC1)c1nc(C)cs1 +COc1cccc(NC(=O)C2Cc3ccc(Cl)cc3C(=O)O2)c1 +Cc1cnn(CC2CN(c3c(C#N)c(=O)n(C)c(=O)n3C)CCO2)c1 +O=C(Nc1ncn(C2CCCCC2)n1)C1CCCO1 +O=C1CCc2c1cnc1nc(NCCN3CCOCC3)[nH]c(=O)c21 +COc1cc2cccc(OC)c(=O)c2c(OC)c1OC +CC(CO)(CO)NC(=O)c1cc2cc(F)ccc2o1 +Cc1ccc(C)c(C(=O)CCC(=O)N2CCn3c2nc2ccccc23)c1 +Cc1ccc(CNc2ccc3nnc(C4CCC4)n3n2)o1 +COCc1nc(COc2ccc(C)cc2)sc1CO +CC(NC(=O)Nc1ccc2oc(=O)n(C)c2c1)c1ccccc1 +Cc1cnn(-c2ccc(C(=O)OCCCc3cccc(C)n3)cc2)c1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)N=c1[nH]nc2ccccn12 +COc1ccnc(CN2CC(=O)N(C)c3ccccc3C2=O)c1 +CC(C)(C)C(=O)NCCC(=O)Nc1cnn(-c2ccccc2Cl)c1 +CC(NC(=O)c1ccc[nH]c1=O)c1cccc(F)c1 +CC(C)N(C(=O)CN1CCN(CCO)CC1)C1CCCC1 +CC(O)CNC(=O)c1nn(C)c2ccccc2c1=O +O=C(CNC(=O)c1c[nH]c2ccccc2c1=O)Nc1ccn[nH]1 +Cc1ccc(C)n1-c1c(C(=O)N2CCOC(C)(C)C2)cnn1C +CCC(=O)NCc1cccc(-c2ccc(S(=O)(=O)NC)cc2)c1 +COc1ccc(OC)c(C(C)NC(=O)Nc2nnc(C)s2)c1 +O=C1CC(C(=O)Nc2cc(Cl)ccc2F)c2ccccc2N1 +COc1ccc(S(=O)(=O)N2CCOCC2(C)C)cc1F +CN1CCN(C(=O)c2cc(Br)c[nH]2)C(c2ccccc2)C1 +CCN(Cc1cccs1)C(=O)c1cccc(NS(C)(=O)=O)c1 +O=C(NCc1ccco1)c1cc2cc(F)ccc2[nH]1 +CC1Oc2ccccc2N(CC(=O)NC(C)c2ccccn2)C1=O +O=C(CCNC(=O)c1cnn2c1SCC2)NCC1CCCCC1 +COc1cc(C)ccc1NC(=O)NCC1CCCOC1 +Cc1cccn2c(CN(CC(O)c3ccccc3)C3CC3)cnc12 +COc1ccc(OC)c2sc(NCc3cccnc3)nc12 +CCN1CC(C(=O)NCCNC(=O)c2ccc(OC)cc2)CC1=O +Oc1cccc2c1CCNC2COc1ccc(F)cc1 +CC(CC(=O)Oc1ccccc1F)c1ccccc1 +O=C(Nc1nnc(Cc2ccccc2)s1)c1ccccc1 +Cc1nn2ccccc2c1C(=O)NCCOc1ccc2c(c1)OCO2 +Nc1cc(C2CCN(C(=O)c3ccc(Cl)cc3)CC2)no1 +COc1ccc(-c2nnc(NC(=O)c3n[nH]c4c3CCC4)s2)cc1 +COc1ccc(C(=O)CNC(=O)c2ccccc2OC)cc1 +COC(=O)c1c(C)oc2cc(C)c(NS(C)(=O)=O)cc12 +Cc1nc(N(C)C)cc(N2CCN(S(=O)(=O)N(C)C)CC2)n1 +Cc1ccc(NC(=O)c2cc(C)n(C(C)C)c2C)cc1S(C)(=O)=O +O=C(Nc1cccc(-c2nnnn2C2CC2)c1)C1CCC1 +O=C(NCC(O)c1ccc(F)cc1)Nc1ccccc1OCC1CC1 +CCOC(=O)C1CCN(Cc2nc3ccccc3n2C(F)F)CC1 +CC(C)(C)c1ncc(CN2CCC(n3cccn3)CC2)s1 +O=C(Nc1cccc2cn[nH]c12)c1ccccc1Cl +CCc1noc(CSc2nnc(N3CCOCC3)n2C)n1 +Cc1nc2ccc(Cl)cc2cc1C(=O)N1CC(C)OC(C)C1 +Cc1nc(NC(C)c2ccc3c(c2)OCCCO3)c2cnn(C)c2n1 +CCN(C(=O)CNc1c(F)cccc1F)c1ccccc1 +Cn1nccc1C(=O)N1CCCC1c1ccc(F)cc1 +C=CCN1CCN(C(C)C)C(=O)C12CCN(C(=O)c1cc[nH]n1)C2 +O=C(Nc1ccsc1-c1nnc(C2CC2)o1)c1ccccc1F +CCOc1ccccc1N1CCN(C(=O)c2ccc(=O)n(C)c2)CC1 +Cc1cnn(C2CCCN(C(=O)c3cccnc3N(C)C)C2)c1 +O=C(CC1CCCO1)NCCCc1ccc(Cl)cc1 +COc1cccc(CN(C)C(=O)Cn2cnc3ccccc32)c1 +N#Cc1cn(-c2ccc(NC(=O)CCC3CCCOC3)cc2)nc1N +COC(=O)c1ccc(NC(=O)C(O)c2ccc(C)cc2C)cc1 +Cc1ccncc1NC(=O)NCc1ccccc1CN1CCCC1=O +COC(C(=O)NCC(O)c1ccco1)c1ccccc1 +CS(=O)(=O)N1CCc2sc(C(=O)NCc3ccccn3)cc21 +COc1cc(OC)cc(-c2c(CO)nnn2C(C)C)c1 +O=C(Nc1cccc(F)c1)C1CCN(C(=O)c2cccc(F)c2)CC1 +CCCCNC(=O)c1ccc(NC(=O)C(C)C)cc1 +O=C(NC12CC3CC(CC(C3)C1)C2)c1cnn2c1OCCC2 +CCC(C(N)=O)N(c1cccc(Cl)c1)S(C)(=O)=O +Cc1occc1-c1nnc(SCCC(=O)N2CCCC2)o1 +COc1ccc(C(=O)NCc2ccccc2C)cc1F +COc1ccc(CCC(=O)N2CCCC2c2ccc[nH]2)cc1OC +Cc1n[nH]cc1CN1CC=C(c2cccs2)CC1 +CCCCS(=O)(=O)N1CCN(C(=O)c2ccco2)CC1 +CC1(NS(=O)(=O)c2ccccc2)Cc2ccccc2C1 +Cc1noc(C)c1COc1ccc(CN2CC(C)OCC2C)cc1 +CC(=O)Nc1ccc(F)c(NC(=O)c2ccc(F)cc2)c1 +COCc1nn2c3c(cnc2c1-c1ccccc1)C(=O)CCC3 +CCC(=O)N1CCC(c2cc(-c3cccc(F)c3)n(C)n2)CC1 +COc1ncccc1C(=O)NC1CCN(C(=O)OC(C)(C)C)C1 +NC(=O)c1ccc(NCCOc2ccc3ccccc3c2)cc1 +COCc1nnc(-n2nnc(C(C)=O)c2-c2ccccc2)s1 +Cc1nn(C)c(C)c1OS(=O)(=O)c1ccc2c(c1)N(C)CCC2 +O=C(NCCCn1cnc2ccccc2c1=O)c1cnccn1 +Nc1cc(C2CCN(C(=O)COc3ccc(F)cc3)CC2)no1 +Cn1cc(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2)ccc1=O +CC1CCC(C(N)=O)CN1C(=O)CSc1nc2ccccc2o1 +CC1CN(C(C#N)c2cccc(Br)c2)CCO1 +CCc1ccc(C(=O)N(CCO)C2CCCC2)s1 +Cc1c(N)cccc1NC(=O)c1cc(F)cc(F)c1 +Cc1ncsc1C(=O)Nc1ccc2[nH]ncc2c1 +Fc1ccc2c(c1C(F)(F)F)C(c1cncnc1)NCC2 +COc1cc(NC(=O)COc2ccc(Cl)c(C)c2)ncn1 +O=S(=O)(NCCc1ccc(O)cc1)N1CCCCCC1 +CCc1onc(C)c1NC(=O)C(C)NC(=O)c1n[nH]c2ccccc12 +CCc1ccccc1CC1Oc2cc(O)ccc2NC1=O +Cc1cc(OC(C)C(=O)NC(C)c2c(C)noc2C)ccc1Cl +O=c1ccnc(C=Cc2cc(F)ccc2Br)[nH]1 +Cc1scc(C(=O)N2C3CCC2CC(=O)NC3)c1-c1ccccc1 +CN(Cc1cccc(C#N)c1)C(=O)C1Cc2ccccc2C(=O)O1 +Nc1nc(S(=O)(=O)CCCc2ccccc2)n[nH]1 +O=C(NCCc1cccs1)c1cnc(N2CCCC2)nc1 +Cc1ccccc1C(=O)NC(C)c1ccc2c(c1)OCCO2 +O=C(Cc1cc2ccccc2[nH]c1=O)Oc1ccc(F)cc1 +O=c1cc(CO)oc(C(Nc2ccccc2)c2ccccc2)c1O +COc1cccc(NC(=O)N(CCCO)C2CCc3ccccc32)c1 +CN(C)C(=O)Sc1cccc(NC(=O)Cn2ccccc2=O)c1 +O=C1CCN(C(=O)c2ccccc2Cl)CCN1 +O=C(CCn1cncn1)N1CCCCC1CCc1cccs1 +Cn1cc(Br)cc1C(=O)NCc1cccnc1 +CC(NC(=O)C1CC1)c1ccc(NC(=O)c2ccncc2)cc1 +CN(C)C(=O)CC1Sc2ccccc2NC1=O +Cc1nc(-c2nc[nH]n2)sc1C(=O)NC1CC1c1ccc(F)cc1 +CCn1c(C)nnc1CS(=O)(=O)c1nccn1-c1cccc(F)c1 +CCOC(=O)c1c(C)[nH]c(-c2csc(-c3ccoc3)n2)c1C +CC(C)C(C)NC(=O)CNc1ccc(-c2nnnn2C2CC2)cc1 +CC(C(=O)O)=C1Oc2ccccc2Oc2ccccc21 +CNc1cc(C(=O)N2CCC(c3nc4c(C)cccc4[nH]3)CC2)ccn1 +O=C(NCC1(C2CC2)CC1)N1CCc2cc(F)ccc2C1 +COc1ccc(C(=O)N2CCC(CN3CCOCC3)CC2)cc1 +Cc1ccc(NC(=O)c2ccc(-c3ccncc3)nc2N)nc1 +Cc1cc(NC(=O)C(C)OC(=O)c2cc(C)n(C3CC3)c2C)on1 +COc1cc(S(=O)(=O)N=c2cccc(C)[nH]2)c(C)cc1C +COc1ccc(NC(=O)CCCCO)c(OC)c1 +CC(C)CN(C)C(C#N)c1ccc2c(c1)OCCO2 +C=CCN(Cc1cccs1)C(=O)c1ccc(CNC(N)=O)cc1 +N#Cc1cccc(C(=O)Nc2ccc(C(=O)Nc3cccnc3)cc2)c1 +COc1ccc(C(=O)CCC(=O)Nc2cnn(C)c2)cc1F +Cc1ccc(OCc2cccc(C(=O)N(C)CCC#N)c2)cn1 +CSc1nnc(CN2CCN(S(C)(=O)=O)CC2)s1 +COc1ccc(C2(C(=O)N3CCCC(O)(CO)C3)CC2)cc1 +Cc1cccnc1CNC(=O)Nc1cnn(-c2ccccc2F)c1 +COCCN(C)c1ccc(NC(=O)c2c(C)cc(C)cc2C)nc1 +CCc1nncn1CCNC(=O)N1CCCCCC1c1ccco1 +COCCC(=O)N1CCCC(c2nncn2Cc2ccccc2)C1 +Cc1cc(C(=O)Nc2ccccc2N(C)C)n(C)n1 +CC(C)C(C)NC(=O)CNc1cccc(C(=O)N2CCCC2)c1 +COc1ccc(CN(C)C(=O)CC#N)cc1Cl +COc1nn(C)c(C)c1NC(=O)NCCC1=CCCCC1 +O=C(Cc1cccc(Cl)c1)NCc1cc(=O)[nH]cn1 +O=C1COc2c(Br)cc(C(F)(F)F)cc2N1 +CC(C)Oc1ccccc1NC(=O)c1cnc(C2CCCO2)s1 +COc1cccc(NC(=O)COc2nc(C)nc3ccccc23)c1 +CCCCNS(=O)(=O)c1ccc(NC(=O)CC)cc1 +CCOc1ccc(NC(=O)C(C)NC(=O)c2ccoc2)c(C(N)=O)c1 +CN1C(=O)CC(NCc2cccc(O)c2)C1c1ccc(Cl)cc1 +COc1ccc(OC)c(NC(=O)c2ccc(N3CCCC3=O)cc2)c1 +CC(C)S(=O)c1ccc(C(=O)NCC(C)(C)c2ccncc2)cc1 +CCCNc1nnc(SCC(=O)Nc2nccs2)s1 +O=C(Cc1ccc2c(c1)OCCO2)NCCCN1CCCC1=O +Cc1c(C#N)c2ncnc(-c3ccccc3)c2n1-c1ccccc1 +Cc1cc(C)nc(NC(=O)c2oc3ccccc3c2C)n1 +O=C(Nc1nnc(-c2cccnc2)s1)C1CC1c1ccccc1 +O=C(c1ccco1)N1CCCn2cnc(COCC3CC3)c2C1 +Cc1cccc(COC2CCC3C2OCCN3Cc2cnn(C)c2)n1 +Cc1cc2cc(NC(=O)CN(C)S(C)(=O)=O)ccc2[nH]1 +O=C(Nc1ccccc1)c1nc2ncc(Br)cn2n1 +COc1cccc(C(=O)Nc2nnc(-c3ccco3)o2)c1OC +Cc1cccc(C(=O)NC(C)C(=O)NCc2nnc3ccccn23)c1 +CC(C)CN(C)C(=O)c1csc(CNC(=O)OC(C)(C)C)n1 +CCC(C)NC(=O)COCc1cc(-c2ccc(F)cc2)on1 +Cc1cc2c(cc1S(=O)(=O)NC1CC1)N(C(=O)C1CC1)CC2 +CCN(CC)c1sc(C(C)=O)cc1Br +CCN(CC(F)(F)F)C(=O)c1cccc(COC)c1 +COc1ccc(NC(C)=O)cc1NC(=O)N1CCC(C)CC1 +CC(=O)c1ccc(NC(=O)CNC(=O)C2CCCCC2)cc1 +NC(=O)C(Nc1cccc(N2CCCS2(=O)=O)c1)c1ccccc1 +Nc1nc2n(n1)CC(c1cc(Cl)cc(Cl)c1)CC2 +Cc1cc(=O)[nH]c(SCc2cc(F)ccc2N)n1 +Cc1nn(-c2ccc(C#N)cc2)c(NC(=O)NCc2ccccn2)c1C +Cc1cccc(=NS(=O)(=O)c2ccc3c(c2)CCC(=O)N3C)[nH]1 +O=S(=O)(NCC(O)c1ccccc1F)c1cccc2cnccc12 +NC(=O)C1(CNC(=O)c2cc(F)c(F)cc2Cl)CCOCC1 +Cn1nnnc1SCC(=O)c1sccc1Br +Cn1ncc(N2CCC(CNC(=O)CN3CCCC3=O)C2)cc1=O +COc1ccc(C(=O)NCCCC(=O)NC(C)C)cc1 +CCC(c1cccs1)n1nc(C)c(Cl)c1N +Nc1ccc(Oc2ccc(Cl)c3cccnc23)cn1 +COCC(=O)Nc1ccc(F)c(S(=O)(=O)NC2CC2)c1 +CC(=O)c1ccc(NC(=O)c2nc(N3CCCC3)ncc2Cl)cc1 +CCOc1ccccc1CSc1nccn1C1CC1 +Cc1cccc(C(=O)N(C)Cc2ccccc2F)n1 +CC1COCCN1S(=O)(=O)Cc1cc(-c2ccccc2)no1 +CCOc1ncccc1C(=O)N1CCC(NS(C)(=O)=O)CC1 +O=C(CSc1cn[nH]n1)Nc1ccccc1C(F)(F)F +CN(Cc1ccccn1)C(=O)c1ccnc(SCC(F)(F)F)c1 +CSc1nnnn1-c1cccc(NC(=O)N(C)C2CCCCC2)c1 +CC(=O)Oc1ccc2c(c1)C(=O)c1ccccc1CO2 +O=C(Nc1cnc(N2CCOCC2)nc1)c1ccc(F)c(Cl)c1 +CCCn1ccnc(-n2nc(C)c(Br)c2C)c1=O +CC(C)(NC(=O)Nc1ccc2c(c1)COC2)c1ccc2c(c1)OCO2 +CN(C)c1ccccc1NC(=O)CCc1nc(-c2ccccc2)no1 +CC(C)C(=O)Nc1cccc(NC(=O)CNC(C)c2ccccc2)c1 +Cc1ccc(C(C)NC(=O)CCCC(=O)N(C)C)cc1F +NS(=O)(=O)c1ccc(CCNCc2cscn2)cc1 +CCN1C(=O)C(C)(C(=O)NC(C)C)Oc2ccccc21 +CCc1ccccc1NC(=O)CN1CCN(C(=O)C2CC2C)CC1 +COCCN(Cc1ccc(F)cc1Cl)C(=O)c1cnccn1 +O=C(CCC(=O)N1CCC(O)CC1)c1ccc(F)c(F)c1 +CCC(CC#N)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 +O=C(CNC(=O)Nc1ccc2c(c1)CCC2)Nc1ccc(F)cc1 +Nn1c(SCC2CCCO2)nnc1-c1ccccc1Cl +N#Cc1c(Br)cnn1Cc1cccc(Cl)c1 +CCCCS(=O)(=O)N1CCCC1C(=O)Nc1cc(F)ccc1C +O=C(N1CCC2(CC1)CC2)C1(c2ccc(Cl)cc2)CCOCC1 +O=S(=O)(NCc1ccc(-c2nccs2)cc1)c1cccs1 +CCCn1nc(C(=O)NC2CCC(CC)CC2)ccc1=O +CC1CCN(C(=O)CSc2ncnc3c2oc2ccccc23)CC1 +CCCc1cncnc1N1CCC2(CCC(=O)N(CCOC)C2)CC1 +O=C(Cn1ncc2ccccc2c1=O)Oc1cc(Cl)ccc1Cl +Cc1nn(Cc2noc(C(=O)NCc3cccnc3)n2)c(C)c1Cl +COC(=O)C(Cc1ccccc1)NS(=O)(=O)N1CCCCC1 +CC(C)OCCC(=O)Nc1ccc(-c2nc(C(C)C)no2)cc1 +COc1ccc(-c2cccc(-n3cccn3)c2)cc1C(N)=O +CNC(=O)c1cccc(NC(=O)c2ccc(-c3ccco3)nc2C)c1 +CCCc1nnc(NC(=O)Cc2ccc(O)cc2)s1 +CN(C)C(=O)c1cn2cc(-c3cccs3)n(CC3CC3)c(=O)c2n1 +CCNC(=O)CNC(=O)Nc1ccnc(Sc2ccccn2)c1 +O=C(CC1CCCO1)NCc1ccccc1Cn1cncn1 +Cc1ccc(C(=O)c2ccccc2C(=O)NCc2nncn2C)cc1C +CCCN1CCN(C(=O)Cc2ccccc2C)CC1 +Cc1cc(C)c2c(c1)N(C(=O)c1c[nH]c(C)cc1=O)CCC2 +O=C(c1[nH]nc2c1CCCC2)N1CCC(Oc2ccccc2)CC1 +N#CCC(COc1cc(Cl)ccc1Cl)N1CCCC1 +C#CCn1c(=NC(C)=O)sc2cc3c(cc21)OCO3 +COc1c(Br)c(C(=O)NCc2cnn(C)c2C)nn1C +N#Cc1ccccc1S(=O)(=O)N1CCNC(=O)C1 +CC(C)(C)Oc1cc(CNC(=O)NC(CO)c2ccccc2)ccn1 +Cc1ccc(CNc2ncc3c(=O)[nH]ccc3n2)cc1 +O=S1(=O)N=C(NCC(O)=NCCc2ccccn2)c2ccccc21 +CC(C)OCc1cccc(CNC(=O)c2cnn[nH]2)c1 +NCc1nnc(C(=O)Nc2cccc(F)c2)c2ccccc12 +CC(=O)c1cccc(NC(=O)C2CC(=O)N(C3CCC(C)CC3)C2)c1 +O=C(NC1CC2C(=O)NCC(=O)N2C1)c1cccc2c1OCC2 +CCn1nc(C)c2nnn(CC(=O)NC(C)C)c(=O)c21 +CC(=O)Nc1cccc(NC(=O)CCCNC(=O)c2ccco2)c1 +Cc1occc1C(=O)NCCc1ccc2c(c1)OCCO2 +CC(NC(=O)NCCCSc1ccccc1)C1CCOCC1 +CN(C)C(=O)C1CCN(C(=O)c2cnns2)CC1 +CCN(CC)c1ccc(NC(=O)c2cnn(Cc3ccccc3)c2)cn1 +O=S1(=O)N=C(Cn2nnc(-c3ccccc3)n2)Nc2ccccc21 +CCC(=O)NC1CC2(CCN(c3cccnc3)CC2)c2ccccc21 +CSc1ncc(CN2CCC3(CCCN(CC4CC4)C3=O)C2)cn1 +COc1ccc2c(c1)CCCN2C(=O)NCc1ccccn1 +COCC(NC(=O)C1(c2ccc(Cl)cc2)CCOCC1)C(N)=O +CC(=O)c1cccc(NCC(=O)N(C)C2CCCCC2)c1 +O=C(NCCN1CCOCC1)c1ccccc1COc1ccccc1 +CN1CCC(NC(=O)c2cc[nH]c(=O)c2)C1c1ccc(Cl)cc1 +O=C(Nc1ccc(C(=O)NC2CC2)cc1)c1ccnc(-n2cncn2)c1 +CCCCn1c(N)c(N(Cc2ccco2)C(=O)C(C)C)c(=O)[nH]c1=O +COc1ccccc1CCCn1cncc1-c1cnc(N(C)C)nc1 +CC(=O)N1CCN(C(=O)c2cnn(-c3ccccc3Cl)c2)CC1 +Cn1ncc2c(=O)n(CC(=O)OCc3ccccc3F)cnc21 +NC(=O)CC1CCN(c2cc(Br)ccc2CO)CC1 +Cc1ccc(CN(C)S(=O)(=O)c2ccccc2S(N)(=O)=O)o1 +O=C(Nc1cn[nH]c1)c1cc(Cl)ccc1Cl +CC1CN(Cc2cccc(CNC(=O)Nc3cccnc3)c2)CCO1 +CCn1cc(C(=O)Nc2cnn(-c3ccccc3)c2)cn1 +COCCN(Cc1cccnc1)C(=O)NCc1csc(C)n1 +O=C(Nc1nncs1)C1CCCN(c2ncccn2)C1 +Cc1ccc(-c2noc(-c3c[nH]c4ccccc4c3=O)n2)cc1C +Cc1nnc(C(C)Sc2nc3c(n2-c2ccccc2)CCCC3)o1 +CN(C)C(=O)c1ccc(COc2cc(Cl)ccc2C(N)=O)cc1 +Cc1nc(NCc2ccccc2)sc1C(=O)NCc1cccnc1 +CCOC(=O)C1CCN(C(=O)c2cccc(NC(C)=O)c2)CC1 +CN(C)S(=O)(=O)c1ccc(Cl)c(C(=O)NC(C)(C)C)c1 +Cc1n[nH]cc1CNC(=O)Nc1cccc(C(=O)N2CCCC2)c1 +Cn1c(C(=O)N2CCN(C(=O)c3ccco3)CC2)cc2sccc21 +COC(C)C(=O)Nc1cccc(NC(=O)Nc2ccccc2)c1 +Cc1cc(C(C)(O)CNC(=O)c2c(F)c(F)cc(F)c2F)c(C)o1 +CCN(CC)C(=O)C(C)Oc1ccccc1Cl +COc1ccccc1CCNC(=O)c1cc(Cl)c(OC)c(OC)c1 +CS(=O)c1cccc(NC(=O)CCCc2c[nH]c3ccccc23)c1 +OC(CN1CCN(CC(F)F)CC1)c1ccc(Br)cc1 +COc1ccc(C(=O)Nc2cccc(C)n2)c(O)c1 +CCCc1cc(C(=O)Nc2sc3c(c2C#N)CCCC3)no1 +CCN(CC)C(=O)C(C#N)Cc1cccc(OC)c1 +CCC(NCCNC(C)=O)C(=O)c1ccc2c(c1)NCCO2 +C=CCn1c(CCNC(=O)c2ccccn2)nc2ccccc21 +Cn1ccc(C(=O)N2CCCCC2Cn2cccn2)cc1=O +CCOc1ccc(S(=O)(=O)Nc2cccc(F)c2)cc1 +CCOc1cccc(C(=O)Nc2ccc(OC)cc2)c1 +CNC(=O)c1cc(C(=O)c2ccccc2Br)c[nH]1 +Cn1nc2n(c1=O)CCN(Cc1nc(-c3ccc(Cl)cc3)no1)C2 +N#CCCCNc1ccc(Cl)cc1C(F)(F)F +O=C1c2ccccc2C(O)(C2N=CC=N2)N1CCc1ccccc1 +Cc1n[nH]c(C)c1CCCN(C)c1ncnc2c1c(C)nn2C +COC(=O)c1ccc(C(=O)Nc2ccnn2C(C)C)nc1 +N#Cc1ncn(CC(=O)NCC2COc3ccccc3O2)n1 +Cc1cccc(OCC(=O)OCc2cc(=O)n3c(C)csc3n2)c1 +CCC1COCCN1Cc1ccc(OC(C)C#N)cc1 +COc1cc(N)c(Cl)cc1C(=O)OCC(=O)N1CCCC1 +O=C1CC(C(=O)NCCOCc2ccc(Cl)cc2Cl)CCN1 +CC(C)(C)c1n[nH]cc1CN(CCC#N)Cc1ccccn1 +CCOC(=O)C(CC)Sc1nc2ccccc2c2nnnn12 +O=C(CCc1ccc(Br)cc1F)Nc1ccncc1 +CC(C)NC(=O)c1ccn(COc2ccc(Cl)cc2)n1 +CC(C(=O)NC1CCCc2[nH]c(=O)ccc21)n1cnc2ccccc21 +Nc1cccc(CCC(=O)NCC2COCCO2)c1 +N#Cc1ccc(C(=O)NCCc2ccsc2)cc1 +O=C(NCc1cc(F)ccc1Br)NCC1COCCO1 +COc1cccc(CSc2nnc(C(C)(C)C)n2N)c1 +CCOc1ccc(Oc2nc(N)nc(N(C)C)n2)nn1 +Cn1cc(NC(=O)Nc2cccc(C#Cc3cccs3)c2)cn1 +Cc1ccccc1CC1Oc2cc(N)ccc2N(CC(N)=O)C1=O +COC(=O)c1ccc(C(=O)NCc2csc(=O)[nH]2)o1 +CCC(C)C(=O)NCc1ccnc(-n2ccnc2)c1 +O=C(CCC1CCCC1)N(Cc1ccsc1)C1CC1 +Cc1cc(OCCn2c(=O)oc3ccccc32)ccc1N +Cc1ccc2c(c1Cl)CCNC2c1cncn1C +FC(F)(F)c1cc(-c2ccc3c(c2)OCCO3)nc2ccnn12 +COC(=O)c1ccc2c(=O)n(CCC3=CCCCC3)c(=O)[nH]c2c1 +CCOc1ncccc1NC(=O)c1cncc(Br)c1 +O=C(Cn1ncc2ccccc21)Nc1c[nH]cc(Br)c1=O +Cc1nc(SCC(=O)Nc2cccc3ccccc23)oc1C +CC(NC(=O)CCC=Cc1ccccc1)C(=O)N1CCOCC1 +COc1cccc(CNC(=O)c2ccc3c(c2)OCO3)c1 +CN(Cc1ccc(F)cc1)C(=O)NCC1COc2ccccc2O1 +CCS(=O)(=O)N(C)C1CCN(C(=O)NC2CCC(C)CC2)CC1 +Cc1cc(O)c(C(C)C)cc1NC(=O)c1ccccn1 +CCN(C(=O)CNc1ccc(F)c(C#N)c1)C1CC1 +CC1CC(Nc2cccc(NC(=O)c3ccoc3)c2)C(=O)O1 +Fc1ccc(OCc2nc(-c3ccncc3)no2)c(F)c1 +CC(C)CCC(=O)OCc1nnc(-c2ccc(Cl)cc2)o1 +COC(=O)c1c(-c2ccc(OC)cc2Cl)noc1N +COCc1ccccc1C(=O)Nc1cc(-c2ccccc2OC)n[nH]1 +COc1ccc(C(C)C)cc1C(O)CCC(=O)N1CCCC1 +CC(NC(=O)COc1cccc2c1OC(C)(C)C2)C(N)=O +CCn1cc(CNc2cc(-c3ccccc3F)nc3ccnn23)cn1 +O=C(Nc1ccccc1Cl)C1CCN(C(=O)C2CC2)CC1 +COCCSc1nnc(-c2ccncc2)n1N +COc1ccc(CCCNc2ncccc2C#N)cc1OC +Cc1cc(NC(=O)c2ccco2)sc1C(=O)NCCCO +O=C(Nc1ccc(O)cc1)C1CC=CCC1C(=O)N1CCOCC1 +Cc1nc(C)c(C(=O)N2CCSc3ccccc32)s1 +COCC(C)NS(=O)(=O)c1ccccc1C#N +O=C(c1ccc(-n2cccn2)c(F)c1)N1CCc2ccc(O)cc2C1 +c1ccc2c(c1)nc1n2CN(C2CCCCCC2)CN1n1cnnc1 +CC1(C(N)=O)CN(S(=O)(=O)c2cn[nH]c2)CCO1 +CCOCc1ccccc1NC(=O)c1ccccc1F +COc1ccc(C(=O)CCC(=O)NC2CCCOC2)cc1C +Cc1nc(C2CCCN2C(=O)C2CC2)[nH]c(=O)c1Cc1ccccc1 +CC(=O)c1sc(NC(=O)Nc2ccccc2C(F)(F)F)nc1C +Cc1ccc(OCC(=O)Nc2cc(N3CCOCC3)ncn2)cc1 +CCc1nc(COC(=O)c2ccc3c(c2)CCN3C(C)=O)cs1 +CN(Cc1cccnc1Oc1ccccc1)C(=O)C1CCC1 +Cn1ccc2c(SCc3ccccc3)cc(N)cc21 +Cc1csc(CNC(=O)c2ccccc2OCC2CCCO2)n1 +COC(=O)c1cnn2c1nnc1c(=O)n(-c3ccccc3C)ccc12 +CCOc1ccc(C(=O)N2CCC(CN3CCCCC3=O)CC2)cc1 +Cc1cccc(C(=O)NCCC(=O)N(C)Cc2ccccc2)c1 +Cc1ccc(CN2CCC(O)C2Cc2ccncc2)s1 +COC(=O)C(C)N(c1cc(Cl)ccc1Cl)S(C)(=O)=O +CN(C)C(=O)C(Sc1ncn[nH]1)c1ccccc1 +Cc1noc(C)c1CNC(=O)C(C)S(=O)(=O)c1ccc(F)cc1 +CC(NC(=O)NCCCNS(C)(=O)=O)c1cc2ccccc2o1 +COc1ccc2nc(SCC(=O)Nc3c(C)cccc3C)[nH]c2c1 +O=c1[nH]c(CCSc2nncs2)nc2ccccc12 +CN(CC(N)=O)S(=O)(=O)c1ccc(N)cc1Br +O=C(Nc1nc(C(=O)NCc2ccccc2)co1)c1ccccc1 +FC(F)(F)c1cccc2c1C(Cn1cnnn1)NCC2 +O=C1C(Sc2nc3ncccn3n2)CCN1c1ccccc1F +CC(C)NC(=O)CNc1ncnc2c1cnn2-c1ccccn1 +Cc1n[nH]cc1NS(=O)(=O)c1c(C)nn(CC(C)C)c1C +COc1ccc(C(O)CSc2ccccn2)cc1F +COCCNC(=O)Nc1ccc2c(c1)nc(C)n2C +Cc1cc(OCCCCN2CCOCC2)ccc1Cl +Cc1ccccc1-c1nnn(Cc2cc(=O)n3ccsc3n2)n1 +CC(=O)NCCNC(=O)CCC(=O)c1ccc2c(c1)CCC2 +COc1ccccc1-c1nn(-c2ccccc2)cc1C(=O)N1CCCC1 +CCOc1ccc(NC(=O)C2CCCN2C(=O)C2CC2)cc1C +CC(NC(=O)C1(O)CCCC1)c1noc(-c2ccccc2)n1 +COCCCNC(=O)NC(C)c1ccccc1F +COc1ccc(C(C)=O)c(OCC(=O)N(C)CC2CC2)c1 +CN(C)c1ccccc1NC(=O)N1CCNC(=O)C1 +O=C(c1cn2ccsc2n1)N1CCN(C(=O)c2nc[nH]n2)CC1 +O=S(=O)(c1ccc(CNc2ccc(F)cc2)cc1)C(F)F +CC(CO)C(C)NC(=O)Nc1ccccc1SCC(F)(F)F +C=CCC1(CC=C)CCN1C(=O)c1cc2c([nH]c1=O)CCCCC2 +O=C(COCc1cc(-c2ccc3c(c2)OCO3)on1)NC1CC1 +Cc1ccc(C(=O)CCCC(=O)NCc2cccnc2)c(C)c1 +CC(=O)c1ccc(NC(=O)NC2CCCC2)cc1C +CC(C(=O)NCc1cccc(Cn2ccnc2)c1)c1ccsc1 +Cc1[nH]cc(C(=O)N2CCC(C)C2C)c(=O)c1Br +CCCNC(=O)CN1CCN(c2cccc(Cl)c2C#N)CC1 +O=C(Nc1ccc(-n2cccn2)cc1)c1cc2ccccn2n1 +CC(C)c1ncc(Cl)c(C(=O)N2CCN(c3cnccn3)CC2)n1 +C#CCNC(=O)c1ccccc1SCc1ccc(C#N)cc1 +O=C(Cc1ccc(F)cc1)N1CC(c2nc(-c3ccncc3)no2)C1 +CCC(C)(C)NC(=O)CSc1nnc(-c2ccccc2)n1N +CCC(C)c1ccc(S(=O)(=O)NCc2nncn2C)cc1 +O=C(CN1CCCC1=O)NCC(c1cccs1)N1CCOCC1 +CN(C(=O)c1cnc(C2CCCO2)s1)c1nc2ccccc2s1 +CS(=O)(=O)N(CCN1CCCS1(=O)=O)c1ccccc1F +Cc1noc(C)c1CS(=O)(=O)c1ccc(Br)cc1 +Cc1nnc(CNC(=O)c2cc3ccccn3c2)n1C1CC1 +O=C(NCCc1ccc2c(c1)OCO2)c1cnc(C2CCCO2)s1 +Cn1cc(NC(=O)CCCc2ccccc2)ccc1=O +COc1cccc2cc(-c3nc(-c4cccnc4)no3)c(=O)oc12 +Cc1ccccc1OCCCN(C)C(=O)c1ccc2[nH]cnc2c1 +O=C(c1cccc(NCc2noc(-c3ccccc3)n2)c1)N1CCCC1 +CCSc1nc2ccccc2c2nc(=O)c(C)nn12 +CC1(C)C(NC(=O)c2cccc(-c3ccoc3)c2)C2CCOC21 +Cc1noc(C)c1S(=O)(=O)N(C)Cc1c(Cl)cnn1C +CCOc1cccc(-c2ccn(C(C)C)c(=O)c2C#N)c1 +COc1ccc2[nH]cc(CC(=O)OCC(F)(F)F)c2c1 +CCc1cc(CN(C)C(=O)c2cc(Cl)c(C)c(Cl)c2)on1 +CC(C)N(C1CCC1)S(=O)(=O)c1ccc2c(c1)C(=O)NCC2 +COc1ccc(NC(=O)c2cc(S(N)(=O)=O)c(C)o2)c(C)c1 +COC(C)C(=O)N1CCC(NS(C)(=O)=O)CC1 +CCCn1nc(C(=O)N(C)C2(C#N)CCC2)ccc1=O +CCOc1nnc(CNC2CCc3nc(C)nn3C2)s1 +CC(=O)N1CCC2(C1)CN(S(=O)(=O)c1ccc(C#N)cc1)C2 +CC(C)Cc1nnc(NC(=O)N2CCC(C)CC2)s1 +[H]N=c1n(CC(=O)c2cccs2)c2ccccc2n1Cc1ccccc1 +COc1ccc(C(=O)CCC(=O)Nc2ccc(F)cn2)cc1F +Cc1c(-c2ccnc(C(C)C)n2)nnc2nc(-c3ccccc3)nn12 +Cc1ccccc1CNS(=O)(=O)c1ccccc1N +CN(Cc1ccc(C#N)cc1)C(=O)C1CC2C=CC1C2 +CCOC(=O)c1cnn(Cc2ccccc2C)c1N +CC1CCC(CNC(=O)NC(CO)c2ccccc2)CC1 +COCc1cc(C(=O)NC(C#N)c2ccc(C(C)(C)C)cc2)no1 +CC(C)C(NC(=O)Cc1ccccc1)C(=O)N1CCc2ccccc21 +CC(C)CCNC(=O)CC(C#N)c1ccccc1Cl +CN(C(=O)c1ccc(C(F)(F)F)nc1)c1ncccc1C#N +COC(=O)C(C)CN(C)c1nnnn1-c1ccc(C)cc1 +CCC(C)N(C)C(=O)Cc1ccc(S(=O)(=O)C(F)F)cc1 +Cc1nc2cc(C(=O)N(Cc3noc(C)n3)C(C)C)ccc2[nH]1 +COCCOc1ccccc1NC(=O)c1scnc1C1CC1 +Cn1cc(C(=O)OCCOc2ccc(C#N)cc2)c(C(C)(C)C)n1 +Cc1ccc(S(=O)(=O)N2CCN(CCC#N)CC2)cc1C +Cn1nccc1C(=O)N1CCCC(c2cc(-c3ccccc3)n[nH]2)C1 +CC(NS(=O)(=O)c1ccc(F)cc1C(F)(F)F)c1ccncc1 +Cn1cc(N2C(=O)CC3C2CCN3C(=O)c2ccsc2)cn1 +CCN(C(=O)Cc1nc(-c2ccco2)oc1C)c1cccnc1 +CCC(NC(=O)NCC(=O)N1CCCC1)c1cccs1 +CC(C(=O)NCC(F)(F)F)S(=O)(=O)c1nccn1C +CCn1c(CN(C)C(=O)Nc2cccc(OC)c2)nc2ccccc21 +COc1ccccc1CC(=O)Nc1ccc2oc(=O)[nH]c2c1 +COc1ccc(C)cc1NC(=O)CSc1nnc(C2CC2)n1C +COc1ccc(-c2noc(C(=O)N(C)CCO)n2)cc1OC +COc1ccc(OC)c(C(=O)CSc2nnnn2C)c1 +CCNC(=O)c1ccc(OCCc2ccccc2)cc1 +Cc1occc1C(=O)OCCOc1ccc(S(N)(=O)=O)cc1 +Cc1cn(-c2ccccc2)nc1NC(=O)c1cn(C)nc1C(C)(C)C +CC(C)(C)CC(=O)Nc1ccccc1S(=O)(=O)N1CCOCC1 +Cc1csc(CN(C)C(=O)c2ccc(F)c(Cl)c2F)n1 +Cc1nsc(N2CCN(Cc3cccc(Cl)c3F)CC2)n1 +CC(NC(=O)c1ccc(N2CCCC2=O)cc1)c1nnc2ccccn12 +Cc1nnc(C2Cc3ccccc3CN2Cc2c(F)cccc2F)o1 +COc1ccc(-c2oncc2C(C)=O)cc1C(C)C +CC(C)CC1COCCN1C(=O)Cn1cnc2ccccc2c1=O +Nc1cc(=O)[nH]c(SCC(=O)Nc2ccc(F)c(F)c2F)n1 +Oc1ccc(Br)c2c1CCNC2c1ccco1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)c1sccc1C(C)C +Oc1ccc(-n2nnnc2SCc2cn3cccnc3n2)cc1 +CN(C)C(=O)c1cccc(-c2ccc(=O)n(C)n2)c1 +CC(=O)OCc1c(C)cc(C)c(-c2ncc[nH]2)c1C +COCc1ccccc1NC(=O)NCc1cccc(OC(F)F)c1 +COC(=O)C(C)Oc1ccc(CN2CCOCC2C2CC2)cc1 +Cc1ccc(C)c(NC(=O)N2CCN(C3CCOCC3)CC2)c1 +COc1ccc(C(=O)Nc2ccc(C)cn2)cc1OC +Cc1cc(C(F)(F)F)n2ncc(C(=O)N3CCCCCC3)c2n1 +COc1ccc(C(=O)N(C)Cc2ccc(Cl)cc2)nn1 +CCOC(=O)N1CCN(C(=O)CCc2ccc(CC)cc2)CC1 +CCCOc1cccc(CNC(=O)N2CCC(C(C)O)C2)c1 +COC(=O)C(C)NC(=O)C(C)N1CCN(c2ccc(F)cc2)CC1 +Cc1ccc(S(=O)(=O)C2(C(=O)NCC3CC3)CCC2)cc1 +CC(C)(C(=O)Nc1cn[nH]c1)c1ccc(Cl)cc1 +CC(O)(CCc1ccccc1)CNC(=O)NCc1ccccc1 +Nc1ccc(S(=O)c2ccc(Br)cc2)nc1 +COc1cc(-c2cc3ccccn3c2)cc(OC)c1OC +Cc1ccc(CNC(=O)c2ccc(S(N)(=O)=O)o2)cc1 +Cc1nc2cc(C(=O)NCC3CCCO3)ccc2n1-c1ccccc1 +Cc1c(C(=O)NC(C)C(C)c2ccccc2)cnn1-c1ccncc1 +O=C(NCc1cccc(F)c1)c1ccc(-c2ccc(F)cc2)[nH]c1=O +CCn1ccc(CNC(=O)c2cc3ncc(Br)cn3n2)n1 +O=C(c1ccc2[nH]ncc2c1)N1CCCCC1CCO +CC1CCCC(NC(=O)NCCC(=O)N2CCCCC2)C1 +Cc1n[nH]c(C2CC2)c1C(=O)NCCOCCO +CCc1nc(CC(=O)N(C)c2nc3ccccc3o2)cs1 +Cc1noc2ncnc(NCCCc3nc4cc(Cl)ccc4[nH]3)c12 +CC(C)(C)OC(=O)N(CCCNC(=O)N1CCCC1)C1CC1 +COc1ccccc1OCc1cc(C(=O)N2CCC(O)C2)n[nH]1 +CC(C)CN1CCOC(CNC(=O)CNc2ccccc2Cl)C1 +CN(C)S(=O)(=O)c1ccc(NC(=O)CCC2CCCCC2)cc1 +C1CCC(CSc2nnc(C3CC3)n2C2CC2)CC1 +CC(C#N)CN(C)CC(=O)NCc1ccccc1F +O=C(NC1CCN(C(=O)c2ccc3c(c2)CCC3)CC1)c1ccccc1 +O=C(NCc1cccnc1)C1(c2ccc(Cl)cc2)CCCC1 +CCc1nc(CC(=O)N(C)c2cc(Cl)ccc2OC)cs1 +NC(=O)CC1CCN(C(=O)c2ccc(-n3cccn3)cc2)CC1 +CCCOc1ccccc1C1(C)Nc2ccccc2C(=O)N1C +Cc1ccnn1-c1cccc(NC(=O)Nc2cnn(CC(F)F)c2)c1 +COCCOC(=O)Cc1nc2sc3c(c2c(=O)[nH]1)CCC3 +CC(CO)NC(=O)C1CCN(S(C)(=O)=O)CC1 +CCC(=O)c1ccccc1Oc1nc(OC)cc(OC)n1 +Nc1cccc(C(=O)NCC=Cc2ccccc2)c1 +COc1ccc(-n2nnnc2SCCOc2ccccc2)cc1 +O=C(NCC1CC1)N1CC=C(c2ccc(O)cc2)CC1 +CC(c1ccc(O)cc1)n1ccc2c(cnc3ncnn32)c1=O +CCC1CCC(N(C)S(=O)(=O)c2cn[nH]c2C)CC1 +COc1ccc(O)c2c1C(COCc1ccccc1)NCC2 +O=C(c1c(F)cccc1Cl)N1CCc2cnccc21 +CCNC(=O)c1ccc(OCc2ccc(F)cc2)cc1 +Cn1cnnc1SCc1csc(Nc2ccccc2)n1 +CS(=O)(=O)c1ccc(NC(=O)Cc2cccc3ccccc23)cn1 +CCNC(=O)C1CCN(C(=O)NC2CCc3cc(Cl)ccc32)CC1 +CC(C)Nc1nc(-c2csc(N3CCCC3)n2)cs1 +Cc1nn(C(=O)c2ccccc2)c(C)c1S(=O)(=O)N1CCCCC1 +O=C1CCc2cc(S(=O)(=O)NCc3ccncc3)ccc2N1 +CC(NC(=O)CC(C)(C)C)c1cccc(S(N)(=O)=O)c1 +Cn1c(Sc2ccc(C#N)cn2)nc2ccccc21 +CC(C)NC(=O)c1ccc(-c2ccc3c(c2)CCCC3)nc1N +CCCOc1ccc(NC(=O)c2cc(C)on2)cc1Cl +CC(=O)N1CCc2cc(NC(=O)Cc3ccc(C)cc3)ccc21 +CC(=O)Oc1cc(C)c(CN2CCOCC2)cc1C +Cc1ccc(Cn2cc(NC(=O)C3CCC3)cn2)cc1 +CCn1nc(C)c2c(C(F)F)cc(-c3ccc(OC)c(OC)c3)nc21 +CCn1c(-c2ccccc2OC)nnc1S(=O)(=O)CCO +CC(=O)N(C)CC(=O)N(C)Cc1nc2ccccc2s1 +Cc1ccccc1-c1noc(=O)n1Cc1nc2c(C)cccc2c(=O)[nH]1 +COc1ccc(-c2cc(-c3ccccc3)nc(N)n2)c(OC)c1OC +N#Cc1cc(F)ccc1CSc1nncn1C1CC1 +CCN(CCC#N)C(=O)CCCc1cccs1 +Nc1nc(CN2CCN(c3ccccc3)CC2)nc2ccccc12 +Cc1ccccc1Cn1cccc(-c2nc(C3CC3)no2)c1=O +COc1cc(Nc2nc(C)c(CCO)c(=O)[nH]2)c(OC)cc1Cl +CCCC1CN(C(=O)c2cc(C)nc3c2cnn3C)CCO1 +CCOC(=O)c1cc(-c2ccc(N)cc2)nn1-c1ccccc1 +Cc1cc(C)c2c(n1)oc1c(SCC(=O)N3CCCC3)ncnc12 +CC(C)n1c2ccccc2c2c1cc(C(=O)NC1CC1)n2C +COc1ccc(-n2c(Cn3ccnc3)n[nH]c2=O)cc1OC +Cc1cnc(-c2cccc(NC(=O)NCc3nc(C)c(C)s3)c2)o1 +COC(=O)c1ccc(C)c(NC(=O)CCn2c(C)csc2=O)c1 +Cc1nn(CC(=O)NCc2ccco2)c2ccccc12 +CCCc1nnc(C(=O)N(C)CCCc2ccccc2)o1 +Cc1cc2occ(CC(=O)Nc3ccncc3)c2cc1C(C)C +COc1ccc2nc(SCc3cc(C)on3)[nH]c2c1 +O=c1ccnc(SCc2ccc(Br)cc2)[nH]1 +COC(=O)CN(C(=O)c1ccccc1Br)C(C)C +N#Cc1cccnc1N1CCN(c2ccc(O)cc2)CC1 +CCN(CC)C(=O)c1ccc2c(=O)n3c(nc2c1)CCCC3 +CCc1noc(C)c1NC(=O)N1CCOCC1C1CC1 +CC(C)c1ccc(CN(C(=O)c2ccc3nncn3c2)C2CC2)cc1 +CCCNC(=O)c1ccccc1NC(=O)C1CCC1 +Cc1nc2cc(O)nn2c(C)c1CCC(=O)NCCC(C)(C)C +O=C(CCn1ccccc1=O)N(Cc1ccco1)CC(F)(F)F +O=C(Cc1cccnc1)N1CCC(c2nc3ccc(F)cc3[nH]2)CC1 +Cc1nc(N(C)Cc2ccoc2C)sc1C(C)O +CC(=O)Nc1cnc(C)n1-c1nc(-c2ccccc2)cs1 +COCCCCCN1CCOc2ccc(F)cc21 +O=C(NCC(=O)N1CCN(CCO)CC1)NCc1ccc(F)cc1 +C=CCNC(=O)COc1cccc(-c2noc(C)n2)c1 +Cc1cc(NC(=O)C2(c3ccccc3)CCC2)ccc1C(=O)N(C)C +O=c1onc(-c2cccnc2)n1-c1ccccc1Cl +Cc1nccn1-c1ccc(NC(=O)c2cccc(Cl)c2)cn1 +CC1CCCCN1C(=O)c1cccc(NC(=O)c2ccccc2)c1 +Cc1nn(C)c2sc(C(=O)OCc3cc(-c4ccco4)on3)cc12 +O=C(NCCCN1CCCC1=O)C1CCN(C(=O)c2ccco2)CC1 +CCN(CC)C(=O)CCC(=O)c1ccc(F)c(C)c1 +COC(=O)c1cccc(C)c1NC(=O)c1ccccc1F +CCOCC1CCN(C(=O)Nc2cnc(C(C)(C)C)nc2)C1 +COc1ccc(Nc2nccc3n[nH]c(=O)n23)cc1 +CCN(CC)S(=O)(=O)c1ccc(C(=O)Nc2cccc(C)c2)cc1 +COCc1ccc(C(=O)NCc2ccnc(OC(C)(C)C)c2)cc1 +Cc1cc(C2CCCN2C(=O)Nc2ccc(F)cc2)no1 +Cc1cc(NC(=O)N(C)CC2CCOC2)c(Cl)cc1F +COc1ccc(CNc2nccc(N3CCC(O)CC3)n2)c(OC)c1 +N#Cc1ccc(OCC(=O)N2CCN(c3nccs3)CC2)cc1 +O=C(NCC(F)(F)F)c1coc(NC(=O)c2cnccn2)n1 +CCS(=O)(=O)N(Cc1ccc(C(F)(F)F)cc1)C1CC1 +Cc1cc(CNC(=O)CCc2cccc(Cl)c2)c(C)o1 +Cc1cc(C)n(-c2ccc(NC(=O)c3cc(C(C)C)[nH]n3)cn2)n1 +CN(C(=O)Cc1cc(Cl)ccc1Cl)C1(C#N)CCC1 +Cc1[nH]c2ccccc2c1C(=O)CNc1nccs1 +CNC(=O)c1cc(NC(=O)NC(C)c2ccc(C)o2)ccc1F +CCCNC(=O)c1cccc(C(=O)NC(C#N)C(C)(C)C)c1 +CC(=O)NCCNC(=O)Nc1ccc(Oc2cccc(C#N)c2)cc1 +COc1ccccc1C1(C(=O)N(Cc2ccsc2)C2CC2)CC1 +O=C(NCCCN1CCCCCC1=O)c1ccc(-n2ccnc2)nc1 +CC(C)(C)CC(=O)N1CCSc2ccc(N)cc21 +COc1cc(OC)c(NC(=O)c2ccc3c(c2)CC(=O)N3)cc1Cl +CCCC(=O)Nc1cccc(NC(=O)c2c(C)nn(C)c2C)c1 +CC(C)NC(=O)CN(C)C(=O)Cc1cn2ccsc2n1 +Cc1nc2c(NCC3(N4CCOCC4)CCCCC3)ncnc2[nH]1 +N#Cc1ccsc1NC(=O)Nc1ccc(Cl)cc1 +COC(=O)c1cccc(CCNC(=O)c2ccc3nc(C)ccc3c2)c1 +CCCc1cc(=O)[nH]c(SCC(=O)N2CCC(C)CC2)n1 +CCCCc1ccc(-n2nnc(CO)c2C2CCC2)cc1 +O=C(NCCc1cc(F)cc(F)c1)c1ccn(-c2ccc(F)cc2)n1 +CC(C)(C)c1ccc2c(c1)CNCC2NC(=O)c1ccc(O)cc1 +COC(=O)c1cc(CNC(=O)Nc2ccc(F)cc2)oc1C +c1ccc(-c2n[nH]cc2-c2nc3c(cnn3Cc3ccncc3)[nH]2)cc1 +CCN(CCCNC(=O)N1CCCC(C)C1)S(C)(=O)=O +CCCS(=O)(=O)N1CCCCC1C(=O)Nc1nccs1 +CC(=O)NCCc1csc(C2=CCCN(C3C=CCCC3)C2)n1 +CNC(=O)Cn1nc(C#N)cc1-c1ccc(N(C)C)cc1 +CC1CCc2nn(CC(=O)Nc3ccc(F)c(F)c3)c(=O)cc2C1 +Cc1csc(NC(=O)c2cnn3c(-c4ccccc4)ccnc23)n1 +COc1ccc(-c2noc(C(C)NC(=O)OC(C)(C)C)n2)cc1OC +CCc1nnc2n1CCN(CC(=O)Nc1cccnc1)C2 +CC(C)N(C(=O)c1ccccc1-c1ccc(=O)n(C)n1)C(C)C +COc1ccc(N(C)C(=O)c2ccccc2N)cc1Cl +O=C(CNC(=O)c1n[nH]c2c(Cl)cccc12)NCc1cccnc1 +Cc1ccccc1OCC(=O)NCc1ccc(S(N)(=O)=O)cc1 +COc1ccc(NC(=O)c2cnc3snnc3c2)cn1 +Cc1nn(C)c2nc(C(C)C)cc(C(=O)Nc3ncccn3)c12 +CC(C)c1nc(CNC(=O)Nc2ccc3c(c2)COC3)cs1 +Cc1cc(C(=O)N2CCC(c3nc4ccccc4[nH]3)CC2)c(C)o1 +Cc1csc(NC2CS(=O)(=O)c3ccccc32)n1 +O=C(CCc1cc(Cl)cs1)NCCC(=O)Nc1ccccc1 +O=C(CNC(=O)c1ccoc1)NC(C1CC1)C1CC1 +Nc1ccc(C(=O)N2CCN(c3ccccc3)CC2)nn1 +CC(=O)NC(C)(C)c1noc(-c2csc(-c3ccccc3C)n2)n1 +O=C1CC2CCC(CN1)N2c1cncc(C(=O)N2CCOCC2)n1 +CC(C#N)c1ncc(-c2cccc(Br)c2)o1 +COC(=O)c1cc(OC)ccc1NC(=O)Cc1c(C)nc(C)[nH]c1=O +O=C(Cn1nnc2ccccc21)N1CCC(Nc2cccnn2)CC1 +Cc1cccc(C(C)C)c1NC(=O)CSc1nncn1N +CNC(=O)c1cccc(CCNCc2cc(F)ccc2F)c1 +Cc1ccncc1NC(=O)NC1CCN(c2ccccc2F)C1=O +CC(=O)NC1CCCN(C(=O)NC(C)CCCC(C)C)C1 +CN1c2ccc(Cl)c(N)c2C2(CCOCC2)S1(=O)=O +Cc1cnc(-c2cccc(NC(=O)c3cnn(C)c3C)c2)o1 +CCC(CC)C(=O)N1CCC(NC(=O)c2ccc[nH]2)CC1 +CCN1CC2(CCN(C(=O)Cc3c[nH]c4ccccc34)CC2)OC1=O +COCCN1c2ccccc2N(CCOC)S1(=O)=O +COc1ccc(S(=O)(=O)Nc2cc(C(N)=O)cc(C(N)=O)c2)cc1 +CC=CCOC(=O)C1CCN(c2cnccn2)CC1 +CC(C)CC(O)CNC(=O)Nc1cc2c(cc1Cl)OCCCO2 +Cc1ccncc1NC(=O)N(Cc1ccccc1)CC1CCCO1 +CCC1c2ccccc2CCN1C(=O)c1cccc(-n2cnnn2)c1 +CCCNC(=O)c1cccc(NC(=O)c2nnc(CCC)s2)c1 +CS(=O)(=O)Nc1ccc(S(=O)(=O)NCC2CCCO2)cc1 +CN(Cc1ccc(Cl)cc1)C(=O)c1cc(N)ccn1 +O=C(NCC1(O)CCCCCC1)c1cccc(OCC(F)F)n1 +N#CC(NC(=O)c1ccccc1Cl)c1ccccc1 +CN(C)C(=O)CN(C)C(=O)C1CCN(c2ccc(Cl)cn2)CC1 +CN(C)c1ccc(C(=O)Nc2cccc(C#Cc3ccccc3)c2)cn1 +Cc1cc(C)n(-c2cccc(C(=O)NCc3ccccn3)c2)n1 +Cc1nc(C)c(C2NCCc3ccc(C)c(F)c32)s1 +COCC(C)N(C)c1ccc(S(N)(=O)=O)cc1N +CCn1nnc2c(=O)n(CC(=O)c3ccc(OC)cc3)cnc21 +Cc1noc(C)c1C(=O)Nc1cnc2c(cnn2C(C)C)c1 +COc1ccc2c(CN(C)Cc3ccsc3)cc(=O)oc2c1 +Cc1nc2c3ccccc3nc(SCCOCCO)n2n1 +Cc1cc(C)n2ncc(C(=O)Nc3ccc4c(c3)OCCO4)c2n1 +CN1CC(C(=O)N(C)Cc2csc(-c3ccccc3)n2)NC1=O +Cc1cc(NC(=O)C(C)OC(=O)c2n[nH]c(=O)c3ccccc23)no1 +Cc1ccc(CCCC(=O)NC2(c3ncon3)CCOCC2)s1 +CN(Cc1cccc2cnccc12)C(=O)c1ccc2c(c1)OCO2 +Cc1nn(Cc2ccc(C(=O)n3cccn3)o2)c(C)c1Cl +O=C(c1ccc(F)cc1)N1CCC(C(=O)N2CCCCCC2)CC1 +Cc1ccc2c(c1)N(C)C(=O)C(C)(C(=O)NCc1ccc(C)o1)O2 +CC1(C(=O)Nc2cccc(F)c2)CC1(Cl)Cl +CC(C)Cc1nc2c(Br)cc(N)cc2[nH]1 +CC(CCc1ccco1)NC(=O)Cn1c(=O)n(C)c2ccccc21 +Cc1cc(C)cc(-n2nc(C)cc2NC(=O)NC(C)c2nc[nH]n2)c1 +O=C(NC1CC(=O)N(Cc2ccccc2)C1)c1cc(F)ccc1F +COc1ccc2c(c1)OC(O)(C(F)(F)C(F)F)CC2=O +CCc1ccccc1NC(=O)Nc1ccc(N(C)C(C)=O)cc1 +COCC(C)Nc1ncnc2sc3c(c12)CCC3 +Cc1ccc(F)cc1-n1c(CCCN2CCOCC2)n[nH]c1=O +Cc1nc(C2(NC(=O)COc3ccc(Cl)cc3)CCCCC2)no1 +O=C(CCOc1ccccc1Cl)Nc1ccc2[nH]ncc2c1 +Cc1c(C(=O)NCCCS(N)(=O)=O)oc2ccc(Cl)cc12 +CCS(=O)(=O)N1CCCc2cc(NC(=O)C(C)(C)C)ccc21 +CC(C)n1cnnc1CNC(=O)CCc1cc(Cl)cs1 +N#Cc1cccc(Oc2ccc(NC(N)=O)cc2)c1 +CC(C)NC(=O)CSc1ccccc1C(=O)Nc1ccc(F)cc1 +COc1ccc(-n2cc(CNC(=O)c3sccc3OC)nn2)cc1 +COc1ccc(OC(C)C(=O)N=c2[nH]nc3cc(C)ccn23)cc1 +O=C(Cn1cnc2sccc2c1=O)NCc1c(F)cccc1F +CCC(C)(C)C(=O)NCc1ccnc(OC(C)(C)C)c1 +COc1ccc(F)c(NC(=O)c2csc(NC(C)=O)n2)c1 +CC(O)CSc1nc2c(c(=O)[nH]c(=O)n2C)n1C(C)C +Cc1ccccc1NS(=O)(=O)c1cc(C(N)=O)ccc1Cl +C=CCNC(=O)CCCC(O)c1ccc(Cl)cc1 +Cc1ccccc1C(C)NC(=O)c1ccc(-n2cncn2)cc1 +Cc1cc(NC(=O)CCSc2ccc(F)cc2)on1 +CCN(C(c1cccnc1)c1ccc2c(c1)CCO2)S(C)(=O)=O +Cc1ccc(N2CCC3OCCC3(C(=O)NCC3CC3)C2)nn1 +COc1ccc(OC)c(NC(C)c2cccnc2)c1 +COc1ccccc1C(=O)Nn1cnc2ccccc2c1=O +Cc1nc(C(=O)NCC(=O)Nc2nccs2)cs1 +Cc1nc(CC(=O)N2CCCC(C(=O)c3nccn3C)C2)cs1 +COc1ncccc1C(=O)NC1CCN(c2ccccc2Cl)C1=O +Cc1nnsc1C(=O)N1CCCCC1c1nc2ccc(F)cc2[nH]1 +Cc1oc(-c2ccccc2)nc1C(=O)NCc1ccc(F)cc1 +Cc1noc(C2COC3CN(S(=O)(=O)c4ccccc4C)CC32)n1 +CC(C)(C)C(C#N)NC(=O)c1cnc(C2CCCO2)s1 +Cc1ccc(OCC(=O)c2ccccc2C)c(S(=O)(=O)N(C)C)c1 +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)Nc1nccs1 +CCN(CC1CCCO1)C(=O)c1ccc(F)cc1N +CN(C)S(=O)(=O)N1CC2CCCC2(COCc2ccccn2)C1 +CC(C)C(C)NC(=O)c1cc(N2CCCC2=O)ccc1Cl +O=C(NCC1(C2CC2)CC1)c1cc(N2CCCC2=O)ccc1Cl +O=C(CSc1nncn1-c1ccccc1)N1CCc2ccccc21 +O=C1Nc2ccc(Cl)cc2NC12CCCCC2 +CN(C)c1ccc(C(=O)NCc2ccc(S(N)(=O)=O)s2)cc1 +CCC(CC)C(CNC(=O)N1CCOC(C)(C)C1)N1CCOCC1 +N#Cc1ccccc1NCCC(=O)c1ccccc1 +CCN(CC)C(=O)CN(C)c1cncc(-n2nc(C)cc2C)n1 +Cc1cccc(OC2CN(C(=O)CCc3n[nH]c(C)c3C)C2)c1 +O=C(NCCCN1CCOCC1)c1ccnc(-c2cccs2)c1 +CCn1c(SCc2cn3ccccc3n2)nnc1-c1ccco1 +COc1ccc(C(=O)NCC2OCCc3ccccc32)cc1 +COc1ccc(Cl)cc1NC(=O)CSc1nc2ncccc2o1 +COc1cccc(CC(=O)N2CCC3NC(=O)CC32)c1 +O=C(Nc1cc(N2CCCCC2)ncn1)c1ccc2ccccc2n1 +Cc1ccnc(NC(=O)CNC(=O)C23CC4CC(CC(C4)C2)C3)c1 +CCCCS(=O)(=O)NCC(=O)NC1CCc2c(F)cccc21 +Cc1[nH]ncc1S(=O)(=O)NCCc1cccc(F)c1 +Cc1[nH]ncc1S(=O)(=O)Nc1ccccc1O +Cc1ccc2c(c1)C(NC(=O)NC(C)Cn1cncn1)C(C)C2 +Cc1cccc(Cn2cc(Br)ccc2=O)c1 +CCN(CCC(=O)OC)C(=O)Nc1cccc(C#N)c1 +COc1ccnc(N2CCCN(C(=O)C3CC(=O)N(C)C3)CC2)n1 +CCOC(=O)N1CCC(NC(=O)C2C3CC4CC(C3)CC2C4)CC1 +Cc1csc(=NS(=O)(=O)c2cnn(-c3ccccc3)c2)[nH]1 +CCC(C)NC(=O)CC1NC(=O)c2ccccc2NC1=O +N#Cc1cc(C#N)c(SCCc2cccs2)nc1N +COC(=O)c1nnn(C(C)C(=O)Nc2ccccc2OC)c1N +Cc1cc(CNC(=O)c2cnc(C3CCCO3)s2)ccc1F +CCc1ccc2occ(CC(=O)NCCCN3CCOCC3)c2c1 +CCCc1ncc(C(=O)NC(COC)C(N)=O)s1 +NC(=O)CNC(=O)c1ccccc1C(=O)c1ccc(F)cc1 +O=C1CN(C(=O)CCCOc2ccc3c(c2)CCC(=O)N3)CCN1 +Fc1ccc(-c2nn3c(C4CC4)nnc3s2)cc1Cl +CCC(O)c1cc(C)c2c(c1)C(NC(=O)C(C)C)CCO2 +O=C(Nc1cccc(N2CCOC2=O)c1)c1ccc(F)c(F)c1 +COc1ccc(C(=O)NC2CCCCC2C(C)(C)C)nn1 +Cc1cccc(C)c1OCCNC(=O)Nc1cn[nH]c1 +CCc1nnc(NC(=O)c2n[nH]c3ccccc23)s1 +Cc1ccc2[nH]c(CNC(C)Cc3cccnc3)cc(=O)c2c1 +CNC(=O)c1cccc(NC(=O)CCSc2ccccn2)c1C +CCc1ccc(C(=O)N2Cc3ccccc3CC2C(N)=O)cc1 +O=C(C1CC1)N1CCCC(C(=O)N2CCOC3(CCCC3)C2)C1 +Cc1ccc(Oc2ccc(NC(=O)NCc3ncoc3C)cn2)cc1 +CC(C)(C)OC(=O)N1CC2NCc3ccccc3C2C1 +Cc1ccc(C(O)CNC(=O)c2cccnc2)cc1 +CCc1c(C)cc(C(=O)NC2CC2c2ccccc2)c(=O)n1C +CC(c1cccnc1)N(C)C(=O)NCc1ccc(F)c(Cl)c1 +CCOC(CC)C(=O)Nc1cccc2ccccc12 +O=C(CNC(=O)Nc1ccc2c(c1)OCCO2)NCCO +Cn1cc(NC(=O)N2CCCCC2)c2ccccc21 +Cc1cc(C)n(-c2ccc(C(=O)N3CCCC3c3ccc[nH]3)cn2)n1 +CC(=O)NC(COC(C)=O)C(O)c1ccccc1 +COc1ccc(Cl)cc1-c1ncc(F)c(NCCO)n1 +COCc1cccc(CNC(=O)NCC(C)(C)N2CCOCC2)c1 +Cn1ccnc1SCC(=O)Nc1nnc(C(C)(C)C)s1 +CS(=O)(=O)NCC12COCC1CN(C(=O)C1CCCCC1)C2 +COc1ccc(NC(C)c2nc(C(C)(C)C)no2)cn1 +CC(=O)c1cccc(NCC(=O)NC(C)c2ccccc2)c1 +CC(C)NC(=O)C1CN(C(=O)c2ccsc2)CC12CCOCC2 +O=C(Nc1cnn(CCN2CCOCC2)c1)c1ccccc1Cl +N#CCc1ccc(OCCNc2cc(CO)ccc2Cl)cc1 +CC(C)NC(=O)COC(=O)c1ccccc1NC(=O)c1ccsc1 +CNc1ccccc1S(=O)(=O)Nc1ccc(Br)cc1 +CC12CCC(C(=O)Nc3cccc4ncccc34)(OC1=O)C2(C)C +Cc1ccccc1NC(=O)CSc1nnc(-c2ccccc2)n1N +O=C(COc1cccc2c1NCCC2)N1CCCC1 +CCc1noc(CC)c1CC(=O)Oc1cc(C(=O)N(C)C)ccc1C +Cn1cc(C(=O)N2CCc3ccccc32)ccc1=O +COc1cc(NCc2ccc3c(c2)OCO3)nc(C2CC2)n1 +Cc1nc2ccccc2nc1COC(=O)c1cccn1C +CC(C)(Sc1ccccc1)C(=O)N1CCNCC1 +Cc1cc(C(=O)NCCc2ccc(Cl)cc2)cs1 +O=C(c1ccccc1)N1CCCn2c1nc1ccccc12 +CC(=O)c1ccc2c(c1)N(CC(=O)NCc1ccco1)CC(C)O2 +O=C(COc1cccc(-n2cnnn2)c1)N1CCc2ccccc21 +COc1c(Cl)cc(C(=O)N2CCN(C(=O)CO)CC2)cc1Cl +CCOc1ccccc1CN(C)C(=O)NCc1cnc(C)s1 +CCn1cnnc1CNC(=O)NC(C)c1cccc(OC(F)F)c1 +NC(=O)CCOc1ccccc1NCc1cc2cc(F)ccc2o1 +O=C(COc1cccc(-n2cnnn2)c1)N1CCc2ccccc2C1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1cnccn1 +CCN(C(=O)C1CCC1)C(c1cccnc1)c1ccc2c(c1)CCO2 +COC(=O)c1ccc(C(=O)NC2CCCCC2)nc1 +Cc1nnc(CN2CCN(c3ccccc3-c3ccccc3)C(=O)C2)o1 +COc1cc(C)ccc1NC(=O)c1nn(-c2ccccc2)c(C)cc1=O +CCCNc1ccccc1C(=O)Nc1cccnc1 +CC(=O)Nc1ccc(F)c(NC(=O)CCCc2cccs2)c1 +CC(=O)Nc1ccc(F)c(NCc2ccc(F)c(F)c2)c1 +CC(C)Nc1ccc(F)c(S(=O)(=O)N2CCOCC2)c1 +CCCn1nnnc1NC(=O)c1cc(Cl)ccc1OC +Cc1ccc(SCCN(C)c2nc(C)nc3oc(C)nc23)cc1 +O=C(NCc1ccccc1Cn1ccnc1)N1CCOCC1 +CC(C)(C)OC(=O)Nc1ccccc1C(=O)N1CCCC1CO +O=C(Cc1ccccc1)N1CCN(CCc2ccncc2)CC1 +Cc1ccc2cc3c(nc2c1C)OC(C)C(=O)N(Cc1ccco1)C3 +CCN(C(=O)c1cccc(-c2nnnn2C)c1)c1ccccc1 +Cc1cc(C)c2c(c1)N(S(=O)(=O)CCCCC#N)CCC2 +Cc1nc2nc(SCC(=O)NCC(F)(F)F)nn2c(C)c1C +CCN(CCO)C(=O)COc1cccc(OC)c1 +COc1ccc(OCCCn2cnc(C#N)n2)cc1 +O=C(Nc1ccc2nc(C3CCCO3)[nH]c2c1)c1ccc(F)cc1 +Cc1occc1C(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +N#CC1(C(=O)NCCNc2ncccn2)CCCC1 +COc1ccccc1-c1noc(-c2c[nH]c3ccc(C)cc3c2=O)n1 +CN(Cc1ccccn1)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +COCCn1cnnc1SC(C)C(=O)N1CCCc2ccccc21 +COc1ccc(-c2nnc(SCc3cc(C)on3)n2N)cc1 +COc1ccnc(N2CCCN(C(=O)Cn3cc(C)cn3)CC2)n1 +Cc1ccc(-c2ocnc2C(=O)NCCc2ccco2)s1 +Cc1nc(CNC(=O)Cc2ccc(F)c(F)c2)oc1C +O=c1c(CCC2OCCCO2)c(NCc2ccccc2)c1=O +Cc1ccccc1C(=O)Nc1ccsc1-c1nnc(C2CC2)o1 +CCc1ccc(CN(C)C(=O)Cc2c(C)nc(N)nc2C)nc1 +CCOC(=O)c1ccc(NC(=O)C2CC3CCCC(C2)C3=O)cc1 +Cc1ccc(S(=O)(=O)N2CCC(C(=O)NC3CC3)CC2)cc1C +O=C(NCCOc1cc(N2CCCC2)ncn1)c1ccc(F)cc1F +Cc1ccc(F)cc1NC(=O)Cc1c(C)noc1C +Cc1cc(NC(=O)Cc2noc(C(=O)N3CCNC(=O)C3)n2)no1 +Cc1[nH]nc(NC(=O)CN2C(=O)COc3ccccc32)c1CC(C)C +COCCNC(=O)Nc1ccccc1CN1CC(C)OC(C)C1 +COCCN1CCC2(CCN(S(C)(=O)=O)CC2)C1=O +OCC1CCCN1c1cc(N2CCC(c3cccc(F)c3)C2)ncn1 +Cc1cccnc1NC(=O)CCSc1ccccn1 +CC(C)c1cc(C(=O)N(C)Cc2cc3cc(F)ccc3[nH]2)n(C)n1 +CC(=O)N1CCN(S(=O)(=O)c2c[nH]nc2N)CC1 +Cc1csc(C(C#N)C(=O)CSc2nc3ccccc3n2C)n1 +CC(C)(C)C(O)CCNC(=O)c1ccc(Cn2cccn2)o1 +O=C(NCCN1CCOCC1)c1ccc(-c2cncnc2)nc1 +CCSc1ccc(Cl)cc1C(=O)NCC(C)(C)C(N)=O +COc1ccc(F)cc1NC(=O)CCC1CCC(C)O1 +CCOC(=O)Cc1csc(Nc2ncccn2)n1 +O=C(NCCNC(=O)C1CC2C=CC1C2)c1ccc(F)cc1 +COC(=O)C(C)C(NC(=O)Nc1cccn(C)c1=O)c1ccccc1 +COC(=O)CN(C(=O)c1ccc2ccc(Cl)cc2n1)C1CC1 +Cc1nn(C)c(C)c1CCC(=O)Nc1ccn(C)n1 +CCOC(=O)C1CCc2[nH]c(C(F)(F)F)nc2C1 +COC(=O)CSc1cc(C)nc2c1ccc1cccnc12 +COc1ccc2oc(=Nc3cccc(C(N)=O)c3)c(C(N)=O)cc2c1 +CC(=O)c1cccc(NC(=O)c2cc3c([nH]c2=O)CCCC3)c1 +CCCn1cc(NC(=O)c2ccc(C)cc2)ccc1=O +O=C(C1CC(=O)N(C2CC2)C1)N1CC(Oc2ccccc2F)C1 +Cc1c(C(N)=O)nnn1CC(=O)Nc1ccc(C(C)(C)C)cc1 +CCOc1ccc(CC(=O)N2CCN(CCn3cncn3)CC2)cc1 +CCNC(=O)C(C)NC(=O)C1CCN(C(=O)c2cccs2)CC1 +CC(C)NC(=O)C1CC2CN(S(=O)(=O)N(C)C)CC1O2 +Nc1ccc(Nc2nc(-c3ccccn3)cs2)c(Cl)c1 +Cc1nc(CSc2ccccc2)sc1C(C)(C)O +O=C(c1ccccc1)c1ccc(CNC(=O)C2CC2)s1 +CCc1ccc(OCC(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)cc1 +Cc1nc(C2COCCN2C(=O)c2c(C)noc2C)cs1 +O=C1NC(c2ccc(Oc3cnccn3)cc2)Nc2ccccc21 +Nc1c(Nc2cccc(Br)c2)ncnc1N1CCCC1 +CCC1CCCN(C(=O)c2ccc3[nH]cnc3c2)C1 +COc1ccc(OC)c(NC(=O)C(C)OC(=O)c2ccsc2)c1 +COc1ccc(-n2nc(C)c3c(C(F)(F)F)cc(=O)oc32)cc1 +CC(=O)Nc1cccc(NCc2ccc3c(c2)CCO3)c1 +CCOC1COC2(CCN(C(=O)C3CCOCC3)CC2)C1 +CCOC(=O)N1CCN(Cc2nc(CC3CC3)no2)CC1 +CC(C)(C)C(=O)NCC(=O)N1CC=C(c2c[nH]c3ccccc23)CC1 +Cc1noc(Cc2ccccc2NC(=O)NC(C)(C)C)n1 +Cc1nc2ccccc2n1CC(=O)N1CCCCC1Cn1cccn1 +O=C(NCc1ccc(F)c(Cl)c1)N1CCN(c2cnccn2)CC1 +Cc1cccnc1CN(C(=O)c1cncnc1C)C(C)C +CCc1ccc(CCNCc2c[nH]nc2-c2cccnc2)cc1 +N#Cc1ccc(SC(C(N)=O)c2ccccc2)nc1 +OCCn1c(CC(F)(F)F)nc2cc(F)ccc21 +Cn1c(=O)n(C)c2cc(S(=O)(=O)Oc3ccccc3N)ccc21 +CC(C)c1noc(CSc2nc(C3CC3)nc3ccccc23)n1 +COc1ccc(-c2n[nH]c(NC(=O)Cc3ccccc3OC)n2)cc1 +CC(C)N(Cc1ccccc1)C(=O)c1cccc2[nH]ccc12 +CCC(=O)NCCc1nc2ccccc2n1CC(=O)NC(C)(C)C +CNc1nnc(-c2c3c(nc4ccc(F)cc24)CCC3)s1 +Cc1cc(C)c2c(-c3ccccc3)nc(SCC(=O)N(C)C)n2n1 +CCOC(=O)CC(C)CNC(=O)N1CCC(CO)CC1 +CC(O)CNC(=O)c1cccc(S(=O)(=O)NC2CCCC2)c1 +CCOC(=O)c1cc(C(C)C)sc1NC(=O)C1CCC1 +O=C(Cc1ccc[nH]1)N1CCN(C(=O)CN2CCOCC2)CC1 +CC(C)c1nnc2c(Br)cc(N)cn12 +CN(c1ccc(OS(=O)(=O)N(C)C)cc1)S(C)(=O)=O +O=C(NCC#CCOc1ccccc1Cl)c1ccccn1 +NC(=O)c1ccc(NCC#Cc2ccc(C(F)(F)F)cc2)cc1F +O=C1CCCc2[nH]c(=O)c(C(=O)N(CC3CCCCC3)C3CC3)cc21 +COc1ccc2[nH]cc(C(=O)Nc3cccnc3)c(=O)c2c1 +Cc1ccc(NC(=O)Cn2ccc(=O)n(C)c2=O)nc1 +COCCN1CCN(C(C)c2nnc(-c3ccccc3)o2)CC1=O +CCCn1ncc(-c2ccc(OC)c(C)c2)c(CC#N)c1=O +O=C(COc1cccc(C(F)(F)F)c1)NCc1ccccc1 +COc1ccccc1C(NC(=O)c1ccon1)c1ccccn1 +CC1(C)CN(C(=O)c2ccc(OCC3CCCO3)cc2)CCO1 +Cn1nc(CNC(=O)CCc2ccccc2)cc1-c1cccs1 +Cc1ccc(NCC(=O)NCc2ccccc2)cc1 +Cc1ccc(-c2nnc(-c3ccncc3)o2)c(C)c1 +CCCCc1nc(C)c(C(=O)N2CCCC(n3cncn3)C2)s1 +Cc1[nH]ccc1C(=O)N1CC2CCC1CN(C(=O)N(C)C)C2 +NC(=O)c1cccc(NC(=O)CCc2nc3ccccc3s2)c1 +Cc1ccc(O)cc1NCc1ccc(C#N)cc1F +COC(=O)c1ccc(CCNC(=O)c2cc(C)no2)cc1 +O=C(c1ccccc1)N1CCN(C(=O)C2C=c3sccc3=N2)CC1 +OCC(c1ccccc1)C1NCCc2c(O)cc(O)cc21 +O=S(=O)(Nc1cc(F)ccc1F)c1ccc2c(c1)CCC2 +CC(C)CC1(CNC(=O)C(NC(N)=O)C(C)C)CCCC1 +C1=C(CN2CCC(CN3CCOCC3)C2)COc2ccccc21 +CC1CCCN(C(=O)CN(C)S(=O)(=O)c2ccccc2)C1 +CC(OC(=O)CCC1CCCC1)C(=O)Nc1ccc(C#N)cc1 +CNS(=O)(=O)c1ccc(-n2ccnc2)c(N)c1 +Cc1ccc(S(=O)(=O)N2CCCCC2)c(C)c1C +CC(C)COc1ccc(C(=O)Nc2cccnc2-n2cccn2)cn1 +Cn1ccc(C(=O)N2CCN(Cc3c(F)cccc3Cl)CC2)n1 +CC(NC(N)=O)C(=O)NC1CCOc2ccccc21 +CCC(C#N)N1CCC(NC(=O)c2ccsc2)CC1 +CCCc1nnc(NC(=O)C2CCN(c3ccccc3)CC2)s1 +CCCCN(C)C(=O)CN1CCNc2cc(C)ccc21 +CN(CC1CC=CO1)C(=O)CCc1c[nH]c2ccccc12 +O=C1CCC(C(=O)Nc2nc(-c3ccc4c(c3)OCO4)cs2)CN1 +CN(CC1CCC1)C(=O)Nc1cc(-c2ccccc2)on1 +COCc1nc(C(=O)Nc2ccc(-n3cccn3)c(Cl)c2)cs1 +OC(CSc1nc2n(n1)CNc1ccccc1-2)c1ccccc1 +Cc1ccc(NC(=O)NCc2ccoc2)cc1Cl +O=C(CN1CCOCC1C1CC1)N1CCCCC1 +CC1(C)c2[nH]c3ccccc3c2CC2C(=O)N(CCO)CC(=O)N21 +O=C(NCCS(=O)(=O)N1CCCC1)C1CCCCn2nnnc21 +COc1ccc(C(=O)NCCNc2ncccn2)c(O)c1 +COc1cc(C)cc(OC)c1OCC(=O)N1CCc2ccccc21 +Cc1ccc(OCC(=O)OCc2cc(=O)n3cc(C)sc3n2)cc1 +O=C(CC=Cc1ccc(F)cc1)NCc1n[nH]c(=O)[nH]1 +COC(=O)c1c(C)ccc(F)c1NC(=O)Cn1ccc(=O)n(C)c1=O +COc1ccccc1OCC(=O)N1CCOc2ccc(F)cc21 +CCCC1CN(C(=O)Nc2cc(F)c(OC)cc2OC)CCO1 +CNC(=O)NCC(=O)Nc1nc(C2CC2)cs1 +CC(C)C(NC(=O)c1cccc(S(C)(=O)=O)c1)c1ccccc1 +O=C(NCc1ccc(Br)cc1Cl)NCC1CC1 +CNC(=O)c1cc(C)ccc1NC(=O)C(C)CSc1ccccc1 +COc1ccc(NC(=O)N2CCCC(CNC(C)=O)C2)cc1C +O=C(NCc1ccccc1N1CCOCC1)c1nccc2ccccc12 +CCc1onc(C)c1NC(=O)c1ccc2[nH]ccc2c1 +Cc1nn(C)c(C)c1CNc1nnc(CCC(C)C)o1 +Cc1cc(S(=O)(=O)NCc2cn(-c3ccccc3)nn2)ccc1F +Cc1cc(C)n(CCNC(=O)OC(C)(C)C)c(=O)c1C#N +Cc1cc(C)n2c(SCC(=O)Nc3ccccc3Cl)nnc2n1 +CC(=O)Nc1c(C)cc(Br)cc1Br +CC(C)(C)C(=O)N1CC(n2cc(-c3ccccc3)nn2)C1 +CN(C)c1ccccc1NC(=O)Cn1c(=O)[nH]c2ccccc21 +O=C(CCc1c[nH]c2ccccc12)Nc1ccc2c(c1)NC(=O)CO2 +CCOCCCNC(=O)C(N)c1ccccc1C#N +CCS(=O)(=O)N(CCO)c1cc(Cl)ccc1C +O=C(CNC(=O)OCC(F)(F)F)Nc1ccc2sccc2c1 +Cc1cc(C)n(-c2ccc(C(=O)NCc3cn4cccnc4n3)cc2)n1 +COc1c(C)cc(C)cc1C(=O)c1cccc(N)c1 +O=C(Cc1ccsc1)N1CCC(Oc2ccc(F)cc2)CC1 +Cc1ccc(CNS(=O)(=O)c2c(F)cccc2F)s1 +NC(=O)c1cccc(CNc2ccn(-c3ncccc3Cl)n2)c1 +Cc1cccc(N(C)Cc2nnc(-c3ccccc3F)o2)c1 +CCc1ccc(S(=O)(=O)N(Cc2ccncc2)C2CC2)s1 +CC(NC(N)=O)C(=O)NCC1Cc2ccccc2O1 +O=C(N1CCN(c2ncccn2)CC1)C12CC3CC(CC(O)(C3)C1)C2 +CCCOc1cccc(CN2CCCC(c3nncn3C)C2)c1 +Cc1cc(NC(=O)N2CCC(C(O)c3ccccc3)CC2)no1 +Cn1cc(C(=O)NS(=O)(=O)Nc2cccnc2)c2ccccc21 +O=C(NCC(c1cccs1)N1CCOCC1)C1CCCC1 +CCOC(=O)COC(=O)Cc1ccc(Cl)c(Cl)c1 +CC(C)(C)OC(=O)NCC1CCN(C(=O)Cc2ccccc2F)C1 +CN1CCC(C(=O)NC2CCCCC2c2ccccc2)CC1=O +Cc1nnc(SCc2ccccc2C(F)(F)F)n1CC(N)=O +O=C(NCc1ccc(-c2ccc(F)cc2)o1)N1CCC(O)CC1 +COc1cccc(-n2cc(CN(C)C(=O)c3ocnc3C)cn2)c1 +Cc1csc(NC(=O)NC(C)c2ccccc2C)n1 +CCC(C)NC(=O)c1onc(-c2cccc(OC)c2)c1N +CN(CCc1ccccn1)C(=O)NCc1cccc(C#N)c1 +CC1Cc2nc(N)nn2CC1c1cccc2cccnc12 +COC(=O)c1cccc(NCc2ccc(C#N)cc2)c1 +Cc1nnc(Cn2cnc3c(Cl)cc(Cl)cc3c2=O)o1 +CC(C)c1nnc(NC(=O)C(C)c2cccs2)s1 +O=C(Cc1cn2ccsc2n1)NC1CCC2(CC1)OCCO2 +COc1ccc(NC(=O)Nc2nnc(CC(C)C)s2)cc1 +O=C(NCCc1c[nH]c2ccc(F)cc12)N1CCCC2(C1)OCCO2 +COCCNc1ncnc(NCC2CCCO2)c1N +CNC(=O)C(C)CN(C)C(=O)c1ccc(-n2ccnn2)cc1 +CC(OCC1CCCCO1)C(=O)N1c2ccccc2SCC1C +CN(CCOc1ccc(F)cc1)S(=O)(=O)N1CCOCC1 +COC(=O)c1sccc1NC(=O)c1cccc(C#N)c1 +CCC(O)CN1CCN(C(=O)c2cccc(CC#N)c2)CC1 +Cc1ccc2oc(N3CCN(C(=O)C4CCC4)CC3)nc2c1 +COc1ccc(Cl)cc1NCc1nnc(C(C)(C)C)o1 +CCn1nc(C)c(CNCCc2nc(C(C)C)no2)c1C +O=C(Oc1ccc(N2CCCC2)cc1)c1ccc(-n2ccnn2)cc1 +CC(C)C(C)NC(=O)CSc1ccc(Cl)cc1N +N#Cc1ccc(S(=O)(=O)NCCNC(=O)c2ccc(F)cc2)cc1 +CC(C)NC(=O)CSc1nnc(CCn2ccc(=O)[nH]c2=O)o1 +Cc1ccc(-c2nnc(CCC(=O)OCC3CCC(=O)N3)o2)cc1 +Cc1ccc(C)c(-n2ccnc2S(=O)(=O)Cc2cc(C)no2)c1 +CC1CN(Cc2ccc(S(C)=O)cc2)C(C)CO1 +C#Cc1cccc(NC(=O)CN(C)C(=O)c2ccc(OC)nn2)c1 +CCNC(=O)c1ccc(NC(=O)CNc2ccccc2)cc1 +O=C(NCc1ccc(-c2ccn[nH]2)cc1)NCC1CCCO1 +NCCCN1CCc2c(cccc2C(F)(F)F)C1 +Cc1cc(C(=O)Nc2cccc(NC(=O)c3ccccc3)c2C)n(C)n1 +NS(=O)(=O)c1ccc(C(=O)NCC2(c3ccccc3)CCC2)cc1 +Cc1nc(CNC(=O)NCc2csc(C)n2)cs1 +CC(C)(CNC(=O)c1cc(F)ccc1F)c1ccncc1 +C=CCSc1ccccc1NC(=O)c1ccc(CNC(N)=O)cc1 +Cc1cc(C)c2c(c1)-c1nc(CC#N)sc1CCO2 +O=C(NC(CO)c1ccccc1)c1ccccc1F +O=C(C1CC1)N1CCCn2nc(-c3ccc(F)cc3)cc2C1 +COC(=O)c1cc(F)ccc1CN1CCOCC1C1CC1 +CC(C)CC1CN(C(=O)c2cn3ccccc3n2)CCC1(C)O +O=C(NCc1ccco1)c1cc(C2CC2)nn1-c1ccccc1 +Cc1c(C)c2ccc(NC(=O)c3cccc(C#N)c3)cc2[nH]c1=O +CCOCC1CCCN(C(=O)Nc2cc(OC)ccc2F)C1 +N#CC(C(=O)C1CCOC1)c1cc(F)cc(F)c1 +Cc1cc(C(=O)NC(C)c2cc(C)sc2C)c2c(=O)[nH]n(C)c2n1 +Cn1cc(-c2ncnc3c2CCN(c2ncc(F)cn2)CC3)cn1 +O=C(Cc1ccc(-c2ccccc2)cc1)NCCCn1ccnc1 +COc1cc(OC)c(NC(=O)Cc2c(C)nc(C)[nH]c2=O)cc1F +CN1CCn2cc(S(=O)(=O)NCc3cccs3)cc2C1=O +COc1ccc2c(c1)C(N1CCN(CCO)CC1)C(O)CO2 +O=C(Cc1ccc(F)cc1)n1nnc2ccccc21 +CCc1nc2ccccc2n1CC(O)COc1ccc(F)cc1 +Cc1csc(CCNC(=O)NCC2CCN(c3ccccc3)C2)n1 +CCOc1cccc2n[nH]c(=NC(=O)Nc3cc(C)ccc3OC)n12 +Cc1ccc(NC(=O)Cn2cc(N)ccc2=O)nc1 +CCCC(NCc1nc2cc(Cl)ccc2c(=O)[nH]1)c1ccccc1 +CCCc1ccc(S(=O)(=O)NCc2cnn3ccccc23)cc1 +COc1ccc(NC(=O)c2cn(-c3cc(N(C)C)ncn3)cn2)cc1 +COC(=O)CCC(=O)N1CCOc2cc(N)ccc21 +O=C(CO)N1CCc2onc(C(c3ccccc3)c3ccccc3)c2C1 +CCN(CC(=O)NCc1ccc(Cl)cc1)C(=O)c1ccc(F)cc1 +CS(=O)(=O)N1CCN(C(=O)COc2cccc(F)c2)CC1 +CC1CC(C(=O)Nc2ncn(CC(=O)NCc3ccccc3)n2)C1 +Cc1occc1C(=O)Nc1sc(C)c(-c2ccccc2)c1C#N +CC(C)c1ocnc1C(=O)N1CCC2(CCCC2)CC1 +CCC(C)Oc1ccc(NC(=O)c2ccc(CNC(C)=O)s2)cc1 +CC(=O)NC(C(=O)Nc1ccc2[nH]c(-c3ccco3)nc2c1)C(C)C +CC(NC(=O)NCCc1nc2ccccc2[nH]1)C1CCCO1 +O=C(NCc1ccco1)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCOC1CCN(S(=O)(=O)c2c(C)nn(C)c2C)CC1 +COCCOc1ccccc1NC(=O)C(C)NC(N)=O +CC(NC(=O)CC1CCCCC1)C(=O)Nc1ccc2c(c1)COC2 +CC1CCCC(NS(=O)(=O)c2ccc(O)cc2)C1C +COCC(NC(=O)c1c[nH]nc1-c1ccccc1)C(N)=O +Nc1nccnc1C(=O)OCC(=O)C12CC3CC(CC(C3)C1)C2 +OCc1cc(Oc2ccccc2CN2CCOCC2)ccc1F +N#CCCCn1c(Cc2cccs2)nc2cc(F)c(F)cc21 +Cc1sc2ncn3nc(-c4cnccn4)nc3c2c1C +CCN(CC)C(=O)c1ccc(NC(=O)c2ccc(=O)n(C)c2)cc1 +O=C(Cc1n[nH]c(=O)c2ccccc12)NC(c1ccccc1)C1CC1 +COc1ccccc1C1(CNS(C)(=O)=O)CCOCC1 +CCOCC(=O)NC(C)c1cccc(-n2cccn2)c1 +CC(C)OC(=O)CN1C(=O)CNc2cc(F)c(F)cc21 +Cc1ccc(NC(=O)N2CCCC2C(=O)Nc2cccnc2)cc1 +Cc1nc(C(=O)N2CC(C)OC(C)C2)nn1-c1ccccc1Cl +Cc1cc(C(=O)Nc2nnc(-c3cc(C)oc3C)o2)no1 +O=C1COc2ccc(C(=O)Cc3ccccc3)cc2N1 +COc1ccc(C(=O)NC2(C#N)CCCCC2)c(OC)c1 +COc1ncccc1CNS(=O)(=O)c1cccc(C)c1 +Cc1cc(C)c(NC(=O)C(C)N2CCn3c(nn(C)c3=O)C2)c(C)c1 +CCc1cc(N)cc2c(=O)cc(C(=O)NCCCO)oc12 +Cc1csc(-c2ccc(NC(=O)Cc3ccc[nH]3)cc2)n1 +COc1ccc(CNc2ccc3c(c2)CCN3C(C)=O)cc1 +O=C(Cc1coc2ccc(F)cc12)Nc1cccnc1 +COc1cccc(-n2cnnc2SCC(=O)N(C(C)C)C(C)C)c1 +Cn1c(=O)n(C)c2cc(CNc3ncnc4[nH]cnc34)ccc21 +COCc1cc(C)n(CC(=O)Nc2ccccc2Cl)c(=O)c1C#N +CCNC(=O)c1ccc(CNC(=O)Nc2cc(C)on2)cc1 +CCn1nc(C)c(C(=O)N2CCc3ccccc3C2)c1C +CCSc1nnc(-c2ccccc2)c2sc(C)nc12 +COc1ccccc1CCN(C)C(=O)Cc1cccs1 +CCN(CC)C(=O)c1ccc(NC(=O)CCc2ccccc2)cc1 +Cc1ccc(NC(=O)CNC(=O)c2cccc(Cl)c2)c(F)c1 +COc1cccc2c1ccn2CCC(=O)Nc1cnn(C)c1 +O=c1onc(-c2ccccc2)n1Cc1cccc(F)c1 +C=CCNc1cnn(-c2ccccc2)c(=O)c1Cl +Cc1cccc(C)c1NC(=O)CC1=Nc2ccccc2S(=O)(=O)N1 +CCN1CC(C(=O)N(Cc2ccc(C#N)cc2)C(C)C)CC1=O +COc1ccc(OC)c(CNC(=O)c2cn3cc(Cl)ccc3n2)c1 +O=C(CSc1nncn1C1CC1)Nc1nc2c(s1)CCCC2 +Cc1ccc2c(CC(=O)OCC(=O)N3CCCC3)coc2c1 +Cc1ccc(Cl)cc1NC(=O)c1ccc(=O)[nH]c1 +Cc1nc(-c2cccc(CNC(=O)CCCC(=O)N(C)C)c2)n[nH]1 +CC(C)n1ncc2c1N=C(O)CC2c1cc2ccccc2n(C)c1=O +CCCCc1ccc(NS(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O)cc1 +COc1c(Cl)cccc1NC(=O)c1sc(-c2nc[nH]n2)nc1C +CC(=O)Nc1ncc2c(n1)CC(c1cccc(Cl)c1)CC2=O +CCC(=O)N(Cc1ccco1)c1nc2c(F)cccc2s1 +O=C(NCCn1nc(-c2ccccc2)ccc1=O)C1CCCC1 +COc1ccc(-c2cc(C3CC3)nc3sc(C(N)=O)c(N)c23)cc1 +Cc1ccc(N2CC(C(=O)NC3(C#N)CCCC3)CCC2=O)cc1C +CCOc1ncccc1CNC(=O)N(C)Cc1ccc(SC)cc1 +OCCn1cc(-c2ccc(-c3ccccc3)cc2)cn1 +CN1CCN(C(=O)c2ccnc(C34CC5CC(CC(C5)C3)C4)c2)CC1 +CCCc1cc(C(=O)NCc2ccc(Cl)cc2)no1 +COC(=O)CNC(=O)c1ccc(Cn2cc(Br)cn2)o1 +O=C(Nc1cccc(Oc2ccncc2)c1)c1cccc(F)c1 +Cc1nc(C23CC4CC(CC(C4)C2)C3)[nH]c(=O)c1C +COc1ccc(NC(=O)CCc2ccccc2)c(N)c1 +COc1ccc(CNC(=O)Nc2ccccc2OC(F)F)cc1 +CC(C)n1c(CCO)nc2cc3c(cc21)OCCO3 +COC(=O)c1ccc2c(c1)nc(C)n2-c1ccc(C#N)cn1 +O=S(=O)(CCN1CCOCC1)c1ccc(Cl)cc1 +COc1ccccc1CCNC(=O)CCn1ncc2cccc(C)c21 +CCOC(=O)c1ccc(N(C)CC2COc3ccccc3O2)nc1 +Cc1noc(C(C)Nc2cccc(N3CCCC3=O)c2)n1 +CC1CCCN(C(=O)c2ccc(Cn3cc(Cl)cn3)cc2)C1 +CCCNC(=O)CN1C(=O)c2cccnc2Sc2ccccc21 +C#CCNC(=O)c1cc(S(=O)(=O)NCCOC)ccc1C +Cc1n[nH]c2c(NCCc3c[nH]c4ccccc34)ncnc12 +CCc1ccccc1NC(=O)CCc1c(C)nn(C)c1C +Cc1ccc(S(=O)(=O)Cc2ncc(N)cn2)cc1 +COCCNC(=O)c1cn(-c2ccccc2Br)nn1 +Cc1cc2sc(=NC(=O)CN(C)S(C)(=O)=O)n(C)c2cc1C +CCCCCCSc1nnc(N2CCOCC2)n1C +CC(=O)c1cccn1Cc1ccccc1Br +Cc1cc(Cl)ccc1-n1nnnc1-c1ccc(N)cc1 +CC(C)C(NC(=O)NCCN1CCOCC1)c1ccccc1 +COc1ccc(NC(=O)Nc2c(F)cccc2F)cc1 +O=C(Nc1cc(-c2ccsc2)no1)c1nccc2ccccc12 +CCOC(=O)C1=NC(=O)N=C1C1N=CC(c2ccc(OCC)cc2)=N1 +CN(C(=O)CCc1ccsc1)C(C(N)=O)c1cccc(F)c1 +O=C(Nc1ccccc1-c1ncc[nH]1)c1ncn(-c2ccccc2)n1 +CCCc1cnc(NC(=O)N2CCOC(C)C2C)s1 +COc1ccccc1CCNC(=O)c1nn(C)c(=O)c2ccccc12 +COCc1ccc(CNC(=O)NCCC(C)C)cc1 +Cc1cccc(NC(=O)Cn2cnc3c2c(=O)[nH]c(=O)n3C)c1 +COCC(=O)N1CCc2cc(-c3cn4ccccc4n3)ccc21 +NC(=O)c1ccc(NC(=O)N2CCc3cc(F)ccc3C2)cn1 +CCC(=O)NCC(=O)Nc1c[nH]cc(Br)c1=O +CC(Sc1nnc(Cn2cncn2)o1)c1nc2ccccc2o1 +CC(NC(=O)c1ccc(=O)n(C)n1)c1ccccc1Br +Cn1ccnc1C(=O)c1ccc(NC(=O)CCc2cccs2)cc1 +CCOC(=O)CCc1nc(-c2ccc(Cl)cc2)no1 +COCCCNC(=O)Cn1ncc2c(=O)oc3ccccc3c21 +NC(c1ccncc1)c1nc(-c2ccc3ccccc3c2)cs1 +CN(C(=O)C1CC1)c1ccccc1C(=O)Nc1ccccn1 +COc1ccc2c(c1)C(C(=O)N1CCN(C)CC1)CC2=O +O=C(NCC1(C2CC2)CCC1)c1scnc1C1CC1 +NC(=O)COc1ccc(C(=O)NCC(O)c2ccco2)cc1 +COCCn1c(SCC(=O)Nc2ccccc2C)nc(C)c1C +COc1ccc(-c2ccnc3c2ccn3C)cc1CO +CNC(=O)c1ccc(C(=O)N(C(C)C)C(C)C)cc1 +O=C(CCSc1cccc(Cl)c1)N1CCNCC1 +O=C(c1cccnc1)C1CCN(C(=O)CN2CCCC2=O)CC1 +N#Cc1ccc(CSc2ncn(-c3ccccc3)n2)cc1 +O=C(Cn1cnc2ccccc2c1=O)N1CCOCC1C1CC1 +CC(C)CNC(=O)C(C)Sc1ccc(N)cc1Cl +CC(C)CCNC(=O)Nc1cccc(C(=O)N2CCCC2)c1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)OC(C)Cc1ccccc1 +Cc1nnc(NC(=O)COCc2nc3ccccc3s2)s1 +CC(=O)c1ccc(NCc2cccc(C(=O)N3CCCCC3)c2)cc1 +COC(=O)C(CC(C)C)NC(=O)Nc1ccccc1C +O=C(Cc1ccc(F)cc1F)NCC(O)c1ccsc1 +Cc1cc(N)nc(-c2ccc3c(c2)C(C)(C)C(=O)N3)n1 +CCCCCNc1nccc(-c2c(C)nn(C)c2C)n1 +CNC(=O)Nc1ccn(-c2cccc(C(F)(F)F)c2)n1 +Cc1ccc(C(=O)N2CCC(CSc3ccccc3)C2)c(=O)[nH]1 +Cn1nccc1CNC(=O)Nc1ccc(Cl)c(OC(F)F)c1 +CC1(C)Oc2ccc(NC(=O)c3cc(F)cc4[nH]cnc34)cc2O1 +COc1ccc(NC(=O)c2cc(F)cc3[nH]cnc23)c2cccnc12 +CC(=O)Nc1ccc(O)c(C(=O)NCC(C)N(C)c2ccccc2)c1 +C#Cc1cccc(N(Cc2cccs2)C(=O)c2ccc(=O)n(C)n2)c1 +CC(C)OCC(O)CNc1ccc2ccccc2c1 +COC(=O)c1ccccc1NC(=O)c1ccc2snnc2c1 +CC(=O)NC1c2c(ccc3ccccc23)OCC1COC(C)=O +Cc1ccc2ncc(C(=O)N(C)CC(=O)N(C)C)n2c1 +CN(C)c1ncc(NC(=O)CNC(=O)c2ccccc2)cn1 +Cn1cc(C(=O)CC2CCCN2C(=O)c2ccncc2F)cn1 +Cn1cc(-c2nnc3n(C)c4ccc(N)cc4n23)nn1 +C=CCn1c(C2CC(=O)N(CC3CC3)C2)nc2ccccc21 +Cc1ncsc1C(=O)Nc1nc2cc(F)c(F)cc2s1 +CCOC(=O)C1=C(N)Oc2[nH]nc(C)c2C1c1cccnc1 +COCCNC(=O)C1CCC(=O)N(C)C1c1cccs1 +COc1ccc(CC(C)CNC(=O)c2cnccn2)cc1 +CC=Cc1ccc(OCC(=O)NCc2cccnc2)c(OC)c1 +Cc1cc(C)cc(OCCC(=O)NCC(=O)Nc2cn[nH]c2)c1 +O=C(CCNS(=O)(=O)c1ccccc1)Nc1cccc(F)c1 +CCc1nn(C)cc1C(=O)Nc1n[nH]c(OC)n1 +O=C(COc1ccc(C(=O)c2ccccc2)cc1)Nc1ccccn1 +O=C(NCC1Cc2cc(F)cc(F)c2O1)c1ccc(F)cc1F +Cc1ccc(NC(=O)COc2ccc(C)nc2)cc1 +NC(=O)CCC(=O)Nc1ccc(C(F)(F)F)cc1 +CCC1Oc2ccccc2N(CC(=O)NCC2CCCO2)C1=O +O=C(NC1CCN(C(=O)c2ccco2)CC1)c1csnn1 +CCc1nc2c3c4c(sc3ncn2n1)COC(C)(C)C4 +Nc1cc(-c2cc(NCc3ccccn3)nc3[nH]ccc23)ncn1 +CCOCC1CCCN(C(=O)c2ccc(C)c(F)c2)C1 +CCOC(=O)N1CCN(C(=O)Nc2cccc(C)c2)CC1 +Cc1c[nH]nc1C1CCN(C(=O)c2cscn2)C1 +Cc1cc(S(=O)(=O)N2CCN3CCCC3C2)ccc1F +COc1ccccc1OCC(=O)NCc1cccc(C)c1 +CC(=O)N1CCC(NC(=O)NCC2CC23CCc2ccccc23)C1 +CC1CN(C(=O)OC(C)(C)C)CCN1C(=O)c1ccc(=O)[nH]c1 +CCOC(=O)CC1CCN(C(=O)c2ccnc(SCC)c2)CC1 +COc1ccc(C(=O)N2CC3(C)C4CCC3(C)C2(C#N)C4)cc1OC +O=c1[nH]c(N2CCCCC2)nc2nccc(-c3cccs3)c12 +O=C(NCc1cccc2ccccc12)NCC1(CO)CC1 +CCOc1ccc(F)c(C(=O)NC(C)C(=O)OC)c1F +Cc1ccc(C(=O)NCC(c2cccs2)N2CCCC2)s1 +CCc1ccc(CNc2ccc3nc(C)sc3c2)o1 +COc1ccc(F)c(NC(=O)CNC(=O)Cc2cccc(F)c2)c1 +COc1cc(NC(=O)NC2CCc3c(F)cccc32)cc(OC)c1 +Cc1ccc(C(=O)Cc2c(Cl)cccc2Cl)cn1 +CC(C)n1c(C2CCCN(C(=O)c3ccoc3)C2)nc2ccccc21 +CNC(=O)C1CCCN1C(=O)CSc1ccccc1Cl +CCCC(NC(=O)Cc1n[nH]c(=O)c2ccccc12)c1ccccc1 +COC(=O)Cn1cc(CCN2CCOCC2C2CC2)nn1 +COc1ccncc1NC(=O)c1cnc(Cc2ccccc2)s1 +CC(O)C(NC(=O)C(N)Cc1ccc(O)cc1)C(N)=O +COc1cc(NCc2ccccn2)nc(C2CC2)n1 +Cc1ccc(-c2noc(C3(N4CCOCC4)CCCCC3)n2)nn1 +COCCCNS(=O)(=O)c1ccc2c(c1)CCCC(=O)N2 +CC1CC(C)CN(C(=O)COC(=O)c2ccc[nH]c2=O)C1 +Cc1ccc(NC(=O)c2oc3ccccc3c2C)cc1S(C)(=O)=O +CC(C)C(=O)Nc1ccc(-n2cnc3ccccc32)nc1 +Cc1[nH]c2c(C)ccc(C)c2c1CC(=O)N1CCC(CO)C(O)C1 +Cc1ccc2nc(-n3ccc4c(cnc5ncnn54)c3=O)sc2c1 +CCOc1ccccc1NC(=O)c1nn(-c2ccccc2)nc1C +CCC(CC)CN(CC)C(=O)NCc1ccccn1 +COC(=O)C1CC2CC(=O)CC(C1)N2C(=O)OC(C)(C)C +CN(CCC(F)(F)F)C(=O)CCn1ccc2ccccc21 +Cc1ccc(C(C)N(C)C(=O)NCc2cccnc2)cc1 +Cc1cc(C(=O)OCC(=O)c2c(N)n(C)c(=O)n(C)c2=O)c(C)o1 +COc1ccc(OCCC(=O)NCc2cccc(C#N)c2)cc1 +Cc1cc2c(=O)n(Cc3csc(-c4ccco4)n3)cnc2s1 +CC(C)N(C)S(=O)(=O)N1CCN(c2ncccc2C#N)CC1 +O=C(Nc1ccc2c(c1)OCCO2)c1cc2ccncc2cn1 +O=C(Nc1cc(Cl)ccc1N1CCCC1)N1CCCC1 +CC(=O)Nc1nc(C(=O)N(C)C2C3CC4CC(C3)CC2C4)cs1 +Cc1cnc(NCCn2cccn2)nc1-c1ccnn1C +CC(=O)Nc1cccc(-c2nc(-c3ccc4nncn4c3)no2)c1 +CCCNS(=O)(=O)c1ccc2c(c1)NCC(C)O2 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(F)c(Br)c1 +CCn1cc(NC(=O)c2c[nH]nc2-c2ccccc2Cl)ccc1=O +CN1CCN(C(=O)c2nc3c(Cl)cccc3[nH]2)CC1 +COc1ccc(Cl)c2[nH]cc(Br)c(=O)c12 +Cc1ccccc1N1CCN(C(=O)c2cc(F)ccc2F)CC1 +c1cncc(CN2CCCC(c3cccc(-n4ccnc4)n3)C2)c1 +Cc1cccc(NC(=O)COC(=O)c2ccc(OC(C)C)nc2)c1 +CC1CCCN(C(=O)CS(=O)(=O)c2ccccc2)C1 +CCNC(=O)COc1ccc(NC(=O)Nc2c(C)noc2CC)cc1 +Cn1ccc(CNc2cnn(-c3ccccc3Br)c2)c1 +COCCNC(=O)NCC(C)c1ccccc1OC +CC1CN(C2CCN(C(=O)NCCc3ccccc3)CC2)CCO1 +COCC(C)(NC(=O)CCc1ccccc1Cl)C(N)=O +CC(=O)c1c(C)[nH]c(C(=O)Nc2cnc(C(C)(C)C)nc2)c1C +O=C(c1ccccc1O)N1CCOC2CCCCC21 +Nc1nc(CN2CCN(C(=O)c3ccc[nH]3)CC2)nc2ccccc12 +O=C(Cc1cccnc1)N1CCCC(c2n[nH]c(C3CC3)n2)C1 +C=CCN1CCN(C(=O)Nc2ccc3c(c2)OCCO3)CC1 +CCOC(=O)c1ccc(NCC(=O)Nc2c(C)cc(C)cc2C)nc1 +CCC(C)NC(=O)CCN1C(=O)CCc2ccccc21 +O=c1[nH]c2cc(Cl)ccc2c(=O)n1Cc1ccc(F)cc1 +CC(=O)NC(CC(=O)NCCc1cc(C)cc(C)c1)c1ccccc1 +CCS(=O)(=O)NCCn1nnn(-c2cccs2)c1=O +CC(=O)c1cccc(S(=O)(=O)N2CCCCC2C2OCCO2)c1 +CC1CCCCC1N(C)c1nc2sccn2c1CO +O=C(c1ccncc1)N1CCC(O)C1Cc1ccccc1 +N#Cc1cccc(C(NCC(F)(F)F)C(N)=O)c1 +CSc1nccc(S(N)(=O)=O)c1OC1CC1 +COc1ccc(C(=O)N=c2[nH]c3ccccc3[nH]2)nn1 +N#Cc1cccc(COc2ccc(NC(=O)c3cccnc3)cc2)c1 +Cc1cc(F)ccc1NC(=O)NC(CCO)c1cccs1 +CNC(=O)c1cccc(OCc2nnnn2-c2ccccc2)c1 +Cc1nn(C)c2ncc(C(=O)NCCCCN3CCOCC3)cc12 +N#CCOc1cccc(CC(=O)NCCc2cccnc2)c1 +CC(=O)c1c(F)cccc1NCCn1c(C)nc2ccccc21 +COC(=O)N1CCN(CCc2ccc(OC)cc2)CC1 +COc1ccccc1CNC(=O)c1c2c(cn1-c1ccccc1)CCC2 +CNC(=O)CN1CC(C)Nc2cc(Br)ccc21 +CCOC(=O)C1CCCN1C(=O)c1ccc(C)nc1 +Cc1nc2oc3ccccc3c(=O)c2c(=O)n1-c1ccccc1 +Cc1cc(NCc2occc2C)c2ncccc2c1 +O=S(=O)(NCCc1cscn1)c1cc(Cl)cc2c1OCC2 +CC(CN(C)C(=O)Nc1cnn(C(C)C)c1)c1nccs1 +CC(C)(C)C(NC(=O)NCCN1CCOCC1)c1ccccc1 +CC1Cc2ccccc2N1Cc1nc(-c2ccco2)no1 +COCc1cccc(CNC(=O)Nc2ccc3c(c2)COC3)c1 +CC(C)C(=O)N1CCC(C(=O)NCC(=O)NC2CC2)CC1 +CCC1C(=O)NCCN1C(=O)c1cnc(C2CCCO2)s1 +O=S(=O)(NCCc1cnn(-c2ccccc2)c1)c1ccccc1 +COCc1ccc(S(=O)CC(=O)NCc2sccc2C)cc1 +O=C1CN(S(=O)(=O)c2ccc(Cl)c(C(F)(F)F)c2)CCN1 +COCCNc1nc2ccc(S(=O)(=O)C(C)C)cc2s1 +COc1ccc(Cn2ccc(=O)[nH]c2=O)cc1Br +O=C(c1ccc(NCc2ccc(F)cc2F)cc1)N1CCOCC1 +CCOc1cccc(CNC(=O)NC2CCN(CC(F)(F)F)C2)c1 +N#CCCN(Cc1cccnc1)C(=O)c1cccnc1 +O=C(NC(Cc1ccccc1)C(=O)N1CCOCC1)c1cccs1 +CS(=O)(=O)NC1CCN(C(=O)CCCOc2ccccc2)CC1 +COC(=O)C(C)CN(C)C(=O)c1cc(C)cc(C)c1 +C=C(C)CN(CC)C(=O)CSc1nnc(-c2ccccc2)n1N +Cc1nc(CSc2nnc(Cn3cncn3)o2)nc2ccccc12 +CN(C)S(=O)(=O)NCc1cc(Br)c2c(c1)OCO2 +Nn1c(SCc2ncc(-c3ccccc3)o2)nnc1C(F)(F)F +CC(C)CCNC(=O)c1cnc(C2CCCO2)nc1N +O=C(NCc1ccccc1Cn1cccn1)c1cc(F)cc2[nH]cnc12 +Nc1cc(NC(=O)Cc2ccccc2)ccc1Cl +CSc1sc(NC(=O)C2CCCN(C(N)=O)C2)nc1C +O=C(CCC(=O)c1ccccc1)NC1CC(=O)N(C2CC2)C1 +COC(=O)c1ccc(NCC(=O)N(C)C2CCCCC2)cc1 +CC(=O)N(C)CC(=O)N(C)Cc1ccc(C#N)cc1 +CC(Sc1nc2ccccc2n1C)C(=O)N(C)CCC#N +COc1cc(C)c(C(O)CN2CCOCC2)c(C)c1 +CN1CC(NC(=O)c2ccccc2C(=O)c2ccc(F)cc2)CC1=O +COc1ccc2c(c1)c1c(c(=O)n(-c3ccc(C)cc3)c(=O)n1C)n2C +CNC(=O)CNC(=O)NCc1noc(-c2ccsc2)n1 +COc1cccc(-c2cc(CNC(=O)c3cccn(C)c3=O)no2)c1 +CCCc1cc(=O)oc2cc(OC(C)C(=O)OC)ccc12 +Cn1cc(C(=O)Nc2ccc(-c3csnn3)cc2)ccc1=O +O=C(c1cccc(O)c1)N1CCN(C(=O)c2cccc(F)c2)CC1 +CNC(=O)CC1C(=O)Nc2cc(C(=O)OC)ccc2N1C +Cc1nc(CNC(=O)CN(C)S(C)(=O)=O)oc1C +COc1cc(NC(=O)CSc2ccccc2C)cc(OC)c1OC +CC(C)C(O)C1NCCc2c(OC(F)F)cccc21 +COCC(=O)Nc1ccc(NC(=O)c2cc(F)cc(F)c2)cc1 +Cc1ccc(CNC(=O)NCc2cnn(Cc3ccccc3)c2)cc1 +COc1nccnc1NC1CCN(C(=O)c2cccs2)CC1 +COc1ccccc1C(C)NC(=O)COc1ccc(F)c(F)c1 +O=C(Cn1nnc(-c2ccc(Cl)cc2)n1)N1CCc2ccccc21 +COc1ccc(NC(=O)c2ccccc2Cl)cc1-n1cnnn1 +COc1cccc(C(=O)Nc2ccc(CS(N)(=O)=O)cc2)c1F +O=C(Nn1cnc2ccccc21)C1CC1c1ccccc1F +CC(Cc1ccc2ccccc2c1)NC(=O)C(C)n1ccnc1 +CC(=O)c1ccc(C#CCNC(=O)c2ccc(F)c(F)c2)cc1 +COC(=O)c1ccccc1OS(=O)(=O)c1c(F)cccc1F +NC(=O)c1ccc(NC(=O)C2CN(S(=O)(=O)C3CC3)C2)cc1 +CCOc1nnc(CN2CCN(CC(C)O)C(CC)C2)s1 +C=CCN(CC=C)Cc1cc(=O)c(O)cn1C(C)C +Cc1csc(CCC(=O)c2ccc3c(c2)OCCO3)n1 +CCOc1ccccc1CC1Oc2cc(O)ccc2N(C)C1=O +N#CC1(NC(=O)c2cc(Br)ccc2F)CCOCC1 +O=S(=O)(NCC1(O)CCOCC1)c1ccc(C(F)(F)F)cc1 +CC(c1ccccc1)N(C)C(=O)c1ccc(N(C)C)cc1 +C=CCOc1cccc(NC(=O)CNC(=O)C2CC2)c1 +COC(=O)C1CCCCCC1NC(=O)CCn1c(C)csc1=O +CCOc1cccc(C(=O)Nc2c[nH]c(=O)[nH]c2=O)c1 +O=C1CCC2(CCCN(c3ncccn3)CC2)N1CC1CC1 +CCC(NCCN1CCOCC1)c1cccc(Br)c1 +Cc1noc(NC(=O)CCc2ncc(-c3ccccc3)o2)n1 +CCn1ncc2c(C(=O)N3CCC(C)CC3)cc(-c3ccccc3)nc21 +Cc1noc2ncnc(NCc3cc(-c4ccccc4)n[nH]3)c12 +Cc1ccc(N)cc1NC(=O)CCCOC(C)C +COCC(=O)Nc1cccc(NCc2ccc(C)cn2)c1 +O=S(=O)(c1ccc(F)c(F)c1)N1CCNCC1 +Cc1cccc(C(C)C)c1NCC(O)c1cccc(N)c1 +CN(CCOc1ccccc1)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +COC(=O)c1ccc(S(=O)(=O)c2ccc(C(=O)OC)cc2)cc1 +Cn1ccc(C(=O)N2CCN(C(=O)c3ccccc3F)CC2)cc1=O +Cc1ccc(Cl)c(OC(C)C(=O)NCC2CCCO2)c1 +O=C(Nc1nnc(-c2ccno2)o1)C(c1ccccc1)c1ccccc1 +O=C(Nc1ccc(-n2cncn2)nc1)C1OCCc2ccccc21 +N#CCc1ccc(OS(=O)(=O)c2cccnc2)cc1 +COC(=O)C(C)NC(=O)CSc1ccc(C(C)(C)C)cc1 +O=S(=O)(Nc1ccc(Oc2ncccn2)cc1)c1ccc(F)cc1 +CCCCn1ncc(-c2ccc(C)c(C)c2)c(CO)c1=O +O=C(Nc1ccc2c(c1)COC2)c1cc(=O)[nH]c2ccccc12 +CCN1CCOC(C(=O)Nc2ccc(-n3nc(C)cc3C)c(F)c2)C1 +CC(C)(C)C(=O)Nc1nnc(-c2ccccc2)s1 +CCCC1CN(c2cnc3ccccc3n2)CC1NC(C)=O +Cc1ccn2c(=NC(=O)COCCOc3ccccc3)[nH]nc2c1 +CCOc1ccccc1-c1cc(C)cnc1-n1cnnc1 +COc1ccc(Cl)cc1C(=O)N1CC2(COC(C)(C)OC2)C1 +CC(=O)c1c(C)[nH]c(-c2nc(-c3ccc(C#N)cn3)no2)c1C(C)C +CC(=O)NC(C(=O)OCc1ccoc1C)C1CCCC1 +O=C(NCC#Cc1ccc(F)cc1)c1c(F)cccc1F +COc1ccc(C(NC(=O)CCc2ccncc2)C2CC2)cc1 +Nc1ccc2c(ccc(=O)n2CC(=O)N2CCCCCC2)c1 +Cc1cccc(OCC(O)CNC(=O)NCc2ccc(C)s2)c1 +CNC(=O)c1cn[nH]c1C1CCCN1C(=O)c1cnn(C)c1 +Cc1nc(SCC(=O)NCc2ccccc2)n(C2CC2)c1C +Cc1nc(C(=O)N(C)C2Cc3ccccc3C2)cs1 +CNC(=O)CS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +CS(=O)(=O)Nc1ccccc1C(=O)NCc1ccc(Cl)cc1 +CC(=O)Nc1ccc(F)c(NC(=O)NCCCC(C)C)c1 +CCOC(=O)C(NCC1CC1)c1ccccc1Cl +Cn1c(C(=O)N2CCCCCC2)cc2c(=O)oc3ccccc3c21 +CC(C)CCn1nnc(CO)c1C(Cl)(Cl)Cl +Cc1ccc(F)c(NC(=O)N2CCC(NS(C)(=O)=O)CC2)c1 +Cc1cc(C(F)(F)F)c2c(=O)n(Cc3nc(C)c(C)o3)n(C)c2n1 +CCOC(=O)C1CCN(C(=O)CNC(=O)c2cc(C)cc(C)c2)CC1 +Cc1ccc(OCC(=O)Nc2cc(S(C)(=O)=O)ccc2O)cc1C +CC(C)COCCNS(=O)(=O)N1CCCCCC1 +CCC1COCCN1C(=O)NC(C)C1COc2ccccc21 +CCC1CN(C(=O)c2cc(-c3ccccc3Cl)[nH]n2)CCO1 +CCNC(=O)CSc1nnc(-c2cc(Cl)ccc2Cl)n1N +COC(=O)CCC(=O)c1ccc(NC(=O)C2CC2)cc1 +Cc1cc(C(=O)NCc2ccccc2)c2ccccc2n1 +COc1ccc(NC(=O)c2nn(-c3ccc(F)cc3)cc2OC)cc1 +COc1ccc(CC(=O)c2ccc(OC)c(OC)c2)cc1OC +COc1cccc(C(=O)NCc2nc3ccccc3[nH]2)c1 +CCC(=O)N(c1ccc2[nH]c(C)cc2c1)C1CCN(C(C)=O)CC1 +CCCOC(=O)C(C)Oc1cccc(C(C)=O)c1 +OCc1c(-c2ccc(F)cc2)nc2sc(C3CCC3)nn12 +CC(C)CCN1CC2CC(C(=O)N3CCOCC3)C(C1)O2 +Cn1cc(C(=O)Nc2ccc(CNC(N)=O)cc2)cn1 +Cc1cc(C)nc(Nc2cncc(C3CCCN3C(=O)CO)n2)n1 +Cc1nc(SCC(=O)N2CCOCC2)nc2c1CCCC2 +COc1ccc(-c2noc(-c3cc(OC)c(OC)cc3OC)n2)cc1 +Cc1nc(N(C)CCc2noc(C(C)C)n2)c2sccc2n1 +O=C(Nc1cccc(Cn2nc3ccccn3c2=O)c1)NC1CC1 +CC1CN(CC(=O)NC2CCCC2)c2cc(N)ccc2O1 +CCOC(=O)c1nn(-c2ccccc2F)c2[nH]c(=O)cc(C)c12 +Cn1nnc2cc(C(=O)N(C3CCCC3)C3CCCC3)ccc21 +CC(Sc1nnc(Cn2cncn2)o1)C(=O)NC1CCCCC1 +CCOC(CC)C(=O)Nc1ccc(CC(N)=O)cc1 +Cc1ccc(-c2cc(C(=O)Nc3cccc(-n4cnnc4)c3)on2)cc1 +CCN(CC(=O)NCC(F)(F)F)S(=O)(=O)c1ccc(C)cc1 +COc1ccccc1CCNC(=O)Cn1cnc(C2CCC2)cc1=O +CC(=O)Nc1ccccc1C(=O)Nc1ccc(C)cc1 +NC(=O)c1csc(C(=O)OCc2cccnc2)c1 +Cc1ccc(C)c(S(=O)(=O)NCc2ccc(F)cc2)c1 +O=C(c1nnc2sc(-c3ccc(F)cc3)nn12)N1CCCC1 +Cc1oc2ncn(CC(=O)NCc3ccccc3)c(=O)c2c1C +NC(=O)CN(C1CCCC1)S(=O)(=O)C1=Cc2ccccc2CC1 +CCc1nccn1CCN1CCN(CC(=O)Nc2cccnc2)CC1 +Cc1ccccc1Nc1cc(C)n2c(=O)n(Cc3cccnc3)nc2n1 +NC(=O)CCn1cnc2cc(C(F)(F)F)ccc2c1=O +Cc1ccc(Br)c(C(=O)NC2CC2)c1F +COC(=O)COc1cc(C)nc(-c2cnccn2)n1 +CNC(=O)c1c[nH]cc1-c1cc(Br)c2c(c1)OCCO2 +CC(=O)Nc1ccc(NC(=O)C(C)Oc2cccc(N)c2)cc1 +CC(C)Cn1ncc2cc(C(=O)OCC3CCCN3C(N)=O)cnc21 +O=C(c1ccccn1)N1CCOC2C(OCc3ccccn3)CCC21 +O=C(Cc1csc(NC(=O)c2ccccc2)n1)Nc1ccccc1 +N#CC(Cc1cccc(Br)c1)c1cccnc1 +NC(=O)c1nccnc1C(=O)NCCc1csc2ccccc12 +CCc1noc(CC)c1CC(=O)Nc1ccc(F)cc1F +NC(=O)c1ccc(NC(=O)CCCc2nc(-c3ccco3)no2)cc1 +c1cnc(NCc2cncc3c2CCN(Cc2ccco2)C3)nc1 +CC(=O)N1CCN(C(=O)COc2ccccc2F)CC1 +COc1ccc(OC)c(NC(=O)C(C)Oc2ccc3c(c2)OCO3)c1 +C#CCN(C)C(=O)c1cc(Cl)c(OCC=C)c(Cl)c1 +CNC(=O)NCCCc1nn(-c2ccccc2)c(N)c1C#N +COc1ccc(OCCN2C3=NC(=O)CN3c3ccccc32)cc1 +Cc1cc(CNC(=O)CNC(=O)OC(C)(C)C)no1 +COCC(C)N1CCN(Cc2cnc(CC(C)C)s2)CC1 +COc1cccc(OC)c1C(=O)N1c2ccccc2CC1C(N)=O +CN(Cc1ccsc1)C(=O)Cn1cnnc1C#N +CC(C)CC(NC(=O)c1cc2sccc2[nH]1)C(=O)NC1CC1 +C=CCN(c1ccccc1)S(=O)(=O)c1ccc(NC(C)=O)cc1 +CC(C)c1csc(C(=O)N2CCOc3ncccc32)n1 +CCC(CC)C(=O)Nc1ccc(C(O)C2COCC(=O)N2)cc1 +N#Cc1ccc2c(c1)nc(C(F)(F)F)n2-c1ccncc1 +O=C(NCc1ccc2c(c1)OCCO2)NC1c2ccccc2CC1O +O=C(NCc1cccs1)c1ccc2ncccc2n1 +CC(C)(C)NC(=O)OCc1cncc(Br)c1 +O=C(NC1CC1)c1cccc(NC(=O)c2cc(Cl)ccc2F)c1 +Cn1cc(CCCOC(=O)c2cccc(O)c2)cn1 +CCn1nc(C(C)C)cc1C(=O)Nc1cccc2c1OCCO2 +CCC1CN(C(C)=O)CCC1CC(=O)NCc1ccccc1OC +O=C1COc2ccc(Cl)cc2CN1Cc1ccc2c(c1)OCO2 +CC1N(C)C(=O)COC12CCN(C(=O)c1ccc[nH]1)CC2 +O=C(Nc1cc(F)ccc1F)c1cc(=O)[nH]c2ccccc12 +Cn1cc(CNC(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)cn1 +Cc1ncnc(NCc2nc3ccccc3o2)c1C +C#CCN1CCN(CC(=O)N2CCSc3ccccc32)CC1 +COc1ccc(NC(=O)N2CCCC2c2ccco2)c(OC)c1 +COc1ccc(NC(=O)c2ccc(C)cc2)cc1S(N)(=O)=O +CCC(=O)Nc1ccc2nc(NC(=O)CC)sc2c1 +CNC(=O)Nc1cccc(CS(=O)(=O)NC(C)(C)C)c1 +CCc1cccc(NC(=O)COc2cc(C)ccc2C(N)=O)c1 +CC(C)c1ccc(C(O)CCc2nccs2)cc1 +CC1(C)OC(=O)C2=C1NC(=O)CC2c1cc2ccccc2[nH]c1=O +CCCC(=O)NC1CCCN(c2cncc(OC(C)C)n2)C1 +N#CCc1sc(CCc2ccccc2)nc1C1CC1 +O=C(NCCn1ccc2ccccc21)c1c(F)cccc1F +O=C(Cc1coc2ccc3ccccc3c12)Nc1cccnc1 +N#CCCN(CCC#N)C(=O)Cn1c(=O)oc2cc(Cl)ccc21 +CCOC1CC(N(C)C(=O)c2ccc(=O)n(C)c2)C12CCCCC2 +CCCCN1C(=O)COc2ccc(NC(=O)CC)cc21 +COC(=O)c1c(-c2ccc(OC)c(C)c2OC)noc1N +O=C(Nc1cccc(OCc2ccccn2)c1)C1CC1 +Cc1cc(N)ccc1NC(=O)COc1ccccc1C(N)=O +Cc1csc(NC(=O)N(C)C2CCCC(C)C2)n1 +Cc1cnc(NC(=O)c2ccc(Cl)cc2F)s1 +CNC(=O)C(NC(=O)c1ccccc1F)C(C)C +CCN(CCCNC(=O)Nc1ccncc1)C(C)=O +CC(OC(=O)CCC(=O)c1ccc(F)c(F)c1)c1ccccn1 +CN(CCCO)C(=O)c1cc(COc2ccc(F)cc2F)on1 +CC(=O)NC(C)(C)c1noc(-c2cnn(-c3ccc(Cl)cc3)c2)n1 +COc1ccc(CCO)cc1CN1CCOCC1 +Cc1ccc(OCCCC(=O)NCc2ccccc2)cc1 +Cn1cccc1C(=O)N1CCc2noc(-c3ccccc3)c2C1 +COCCc1nc2c(C(=O)OC)ccc(-c3ccccc3)n2n1 +N#CCSc1cccc(C(=O)N2CCOc3ccc(F)cc32)c1 +C=CCNC(=O)NCCNC(=O)c1cccc(OC)c1 +O=C(NCC(=O)N1CCOCC1)c1n[nH]c2cc(Cl)ccc12 +Cc1ccc(OCC(=O)Nc2cc(Cl)ccc2C(N)=O)c(C)c1 +COc1ccc(C)cc1CCNC(=O)NCc1nnc2ccccn12 +COCC(=O)N(C)CC(=O)Nc1cccc(C)c1C +CC(OC(=O)c1cc2ccccc2c(=O)[nH]1)C(=O)c1ccccc1 +CCC(=O)N1CCCN(C(=O)Nc2ccc(C)c(C)c2)CC1 +Cc1ccc(OCc2cccc(C(=O)Nc3nonc3C)c2)cn1 +CC(=O)c1ccc(NC(=O)c2cccc(C)c2O)cc1 +CC1Oc2ccccc2N(CC(=O)NCCc2cccs2)C1=O +CNc1nc(-c2csc(-c3ccccc3OC)n2)cs1 +O=c1ccn(-c2ccccc2)nc1-c1nc(-c2cccs2)no1 +COc1cc(C)ccc1OCCN(C)c1ccccc1N +CC(C)N(Cc1nccn1Cc1ccccc1)C(=O)C1CCC1 +CCOc1ccc(Nc2ncccc2C(=O)Nc2nccs2)cc1 +CN1CCC(Nc2ccc(F)cc2OCC(F)(F)F)C1=O +CC(=O)Nc1ccccc1OCc1noc(C(=O)NCC2CC2)n1 +Cc1cc(C)c(C(=O)NCc2ccc(C#N)cc2)c(C)c1 +CC1CCCCN1C(=O)Nc1ccn(-c2ncccc2Cl)n1 +COCc1nc2cc(F)c(F)cc2n1Cc1ccc(C#N)cc1 +O=C(NCc1ccc(Cl)cc1)NCC1(O)CCc2ccccc21 +CS(=O)(=O)N(C(=O)c1ccsc1)c1cccc(O)c1 +CC(C)(C)C(=O)OCc1cc2ccccc2[nH]c1=O +COc1ccccc1S(=O)(=O)Nc1ccncc1 +COc1ncccc1CNC(=O)NCCOc1ccc(Cl)cc1 +C#CCCN1CCN(C(=O)c2cc(C(C)C)[nH]n2)CC1 +COc1ccc2oc(C)c(C(=O)N3CCN(C)CC3C)c2c1 +O=C(Nc1ccc(F)c(Cl)c1)c1cnc2n(c1=O)CCS2 +Cc1cnc(CNC(=O)CCc2nc(-c3ccccc3)no2)cn1 +Cc1ccc(F)c(NC(=O)N2CCN(C(=O)CCC(C)C)CC2)c1 +Cc1ncsc1CNC(=O)CCN1C(=O)CCc2ccccc21 +COc1cc(C(=O)OC(C)C)cc(Cl)c1OCC(N)=O +CCCc1noc(C2CCCCN2C(=O)C2CCCC2)n1 +O=C(NC1c2ccccc2CC1O)c1ccc(F)cc1 +O=C(NC1CCCc2c1cnn2CCO)N(CC1CCOC1)C1CC1 +C#CCOc1ccc(C(=O)NCc2ccco2)cc1 +CC(C)OC(=O)CCNC(=O)C1CCCCN1C(=O)c1ccccc1 +CC(C)NC(=O)CCCC(=O)Nc1ccccc1C(N)=O +Brc1ccccc1-c1nnnn1-c1ccccc1 +CCC(C)n1nccc1NC(=O)c1cccc(-n2ncc(C#N)c2N)c1 +O=C(NCC(F)(F)F)C1CC1c1cccc(Br)c1 +CC(NC(=O)Cc1ccc(N2CCCC2=O)cc1)c1cccs1 +O=C(NCc1ccc2c(c1)OCO2)NCc1ccc2c(c1)OCO2 +COc1ccc(CNc2cc(F)ccc2F)cc1O +CC(C)CCC(=O)Nc1ccc(-c2nncn2C)cc1 +COC(=O)c1ccc(CN2C(=O)C(=O)c3ccccc32)cc1 +CCn1c(N2CCOCC2)nc2c1c(=O)n(C)c(=O)n2C +CCn1c(CSc2nncn2C2CC2)nc2cc(F)ccc21 +O=C(NCc1cccs1)Nc1ccc(-n2ccnc2)nc1 +C#CCN(C(=O)Cc1ccc(OCC#N)cc1)C1CCCCC1 +CCCn1c(O)nnc1SC(C)C(=O)N(CC)c1ccccc1 +C#CCC(NC(=O)c1ccc2ccccc2c1)c1ccccc1 +CNC(=O)C1(C)CN(C(=O)c2cc(C)nc3onc(C)c23)CCO1 +Nc1nc(N2CCC(Cc3ccccc3)CC2)n[nH]1 +CCCC(=O)Nc1ccc2c(c1)nc(CCn1ccnc1C)n2C +O=C(NCc1ccco1)C1CNCc2ccccc21 +CN(CCC#N)S(=O)(=O)NCC(=O)NC(C)(C)C +CC(C)n1ncc2cc(CNc3nnc(-c4ccncc4)o3)cnc21 +Cc1cc(C)cc(OC(C)C(=O)NCc2cccnc2)c1 +COc1cccc(C(=O)N(C)c2ccccc2F)c1F +CCNC(=O)CN1CCN(C(=O)c2cc(Cl)ccn2)CC1 +Cc1onc(-c2ccncn2)c1C(=O)Nc1cccnc1 +Nc1nc(SCc2ccc(C(F)(F)F)cc2)n[nH]1 +COC(=O)CSc1nc(-c2ccccc2)c2nc(C)sc2n1 +CCOC(=O)C(C)NC(=O)c1[nH]nc(C)c1Br +COC(=O)c1ccc(S(=O)(=O)NC(C)c2cccs2)o1 +Cc1ccc(NC(=O)NC(C)c2nc3ccccc3[nH]2)cc1 +CN(CCc1ccccn1)S(=O)(=O)c1cccc2cccnc12 +CCOc1ccc(S(=O)(=O)Nc2cccnc2)cc1C +CC(Cc1ccccc1F)C(=O)NCc1ccc(C(=O)N(C)C)cc1 +CC(=O)Nc1cccc(-n2nnc(CO)c2C2CCCO2)c1 +CC(NC(=O)C1(C)CC1(Cl)Cl)c1ccc(-n2cncn2)cc1 +CC(=O)N1CC(C)(C)Oc2ccc(C(=O)C(C)N)cc21 +CCn1ccc(C(=O)N2CCC(c3n[nH]c(C)n3)CC2)n1 +CCOc1ccc(NC(=O)NC(C)(C)CO)cc1 +NC(=O)CCOc1ccccc1NC(=O)c1n[nH]c2ccccc12 +CC(C)CC(=O)Nc1ccc(CC(=O)N2CCOCC2)cc1 +Cc1cc(Cl)ccc1NC(=O)c1ccc(F)c(N)c1 +COc1ccc(CN2CCCC(c3nc(C)cc(=O)[nH]3)C2)cc1OC +Cc1ccc(COC(=O)C(N)c2ccccc2)c(C)c1 +COc1ccc(NC(=O)C2(C)Oc3cccnc3N(C)C2=O)cc1F +Cc1ccsc1CNc1ccccc1C(=O)NCc1ncc[nH]1 +O=C(NCc1ccccn1)c1ccc(-n2cccn2)cc1 +Cc1cc(C(=O)N(C)C)c2cnn(Cc3cccs3)c2n1 +Cc1ccc(NC(=O)N2CCC(N(C)c3cccnn3)CC2)s1 +O=C(CCOCC(F)(F)F)N1CCCC(O)C1 +Cc1ccc(C(=O)N(Cc2cccs2)Cc2cccn2C)cc1 +CC1CCCN(C(=O)NC(c2nnc3n2CCC3)C(C)C)C1 +Cc1cccc(NC(=O)Cn2cnc3oc(C)c(C)c3c2=O)c1 +NC(=O)C1CCN(C(=O)NCc2cc(Br)cs2)C1 +Cc1cc(CN2CCN(C(=O)c3cccc(Cl)c3)CC2)no1 +CCc1ccc(S(=O)(=O)NCC2CCCO2)cc1 +O=c1c2ccc(F)cc2ncn1CC(O)COc1ccccc1 +N#Cc1ccc(C(=O)NCC(=O)N2CCOCC2C2CC2)cc1 +CC(C)c1nc(CN(C)Cc2ccc(C#N)cc2)no1 +CCOCC(O)CN1CCN(C(=O)c2cccnc2N(C)C)CC1 +CN(C)C(=O)N1CCN(C(=O)NCc2nc3ccccc3s2)CC1 +Cc1cc(CO)ccc1-n1nc(C)c(Cl)c1C +CCc1c(C#N)nnn1CCOc1ccc(Cl)cc1 +CC(NC(=O)Nc1nncs1)C(O)c1ccc(F)cc1 +O=C1CCN(Cc2cccc(C(F)(F)F)c2)C1=O +CCCOc1cc(NCCc2ccc(F)cc2)ncn1 +N#Cc1ccc(C=CCNc2cnn(CC(F)(F)F)c2)cc1 +CCC(CC)N(CCO)c1ccccc1C(C)O +CCC(CC)C(=O)N1CCC(NS(=O)(=O)N(C)C(C)C)CC1 +COC(=O)c1ccc(CNC(=O)CC2CC3CCC2C3)cc1 +O=S(=O)(c1cccc(Cl)c1)N1CCC(Cn2cccn2)CC1 +CC1CCCCC1NC(=O)Nc1ccc2c(c1)OCC(=O)N2 +O=C(NCCOc1cccc(F)c1)NC(C1CC1)C1CC1 +COC(=O)C1(NCc2ncc(C(C)(C)C)o2)CCC1 +Cn1cc(-c2ccnc(C=Cc3cncnc3)n2)cn1 +Cc1ccc(NC(=O)c2noc3c2CCc2sccc2-3)nc1 +O=C(CC12CC3CC(CC(C3)C1)C2)Nc1ccon1 +CCn1ccc2cc(NC(=O)CC3CCCO3)ccc21 +Cc1nnc(NC(=O)CNC(=O)c2ccc(F)cc2)s1 +CC(c1ccccn1)N1CCN(C(=O)CCc2ccncc2)CC1 +Cn1c(-c2ccc(C(C)(C)C)cc2)nnc1S(C)(=O)=O +Cc1noc(C(C)OC(=O)c2cnn(-c3ccccc3)n2)n1 +CCC1CCCC(NS(=O)(=O)N(C)CCOC)C1 +COC(=O)c1ccc(OC(=O)c2ccoc2C)cc1 +NC(=O)C1CCN(C(=O)c2cc3cc(Cl)ccc3o2)C1 +CCOC1CCN(C(=O)C(C)(C)c2cccc(C(F)(F)F)c2)CC1 +COc1c2c(cc3oc4cccc(O)c4c(=O)c13)OC1OC=CC21O +CN(C)c1nc(NCC2COc3ccccc3C2)ncc1F +CCc1noc(CC)c1CNC(=O)CSc1ccccc1C +CC(=O)N1CCc2ccc(NC(=O)C(C)(C)C)cc21 +CCCn1cc(Cl)cc1C(=O)N(C)CCC(=O)OC +CC(C)C(=O)Nc1cccc(NC(=O)NC(C)c2ccncc2)c1 +CC(C)OC(=O)c1cc(N)c(N2CCOCC2)c(Cl)c1 +N#CCCN(Cc1cccnc1)Cc1ccccc1N +CC(=O)c1cccc(NC(=O)CN(C)c2ccccc2)c1 +Cc1oc(C)c(S(=O)(=O)N(C)C)c1C(=O)Nc1ccccc1F +CCCOC(=O)Cc1cc(C(C)=O)ccc1OC +O=C(c1cc2ccccc2cc1OC(F)F)N1CCC2(C1)OCCO2 +CC(C)C(NC(=O)Cc1ccc(-n2cnnn2)cc1)C(N)=O +Cc1ccc(C(=O)NCCc2cccs2)s1 +O=C(NCCc1csc(-n2cccn2)n1)c1ccccc1F +CC(C)NC(=O)c1ccc(NC(=O)c2cccnc2-n2cccn2)cc1 +C=CCOC(=O)C1=C(C)Nc2ncnn2C1c1sccc1C +CCOC(=O)c1cnc2oc3ccccc3n2c1=O +Cc1nn(Cc2nc(-c3ccsc3)oc2C)c(=O)c(C#N)c1C +OCCN(c1ncccc1C(F)(F)F)C1CCCC1 +COCc1cc(CNC(=O)c2cc(CC(C)C)no2)n[nH]1 +CC(C(=O)N(C)Cc1ccccc1-c1ccccc1)n1ccnc1 +CC1CCCCN1C(=O)c1cc2sc(N(C)C)nc2s1 +N#Cc1cccc(C(=O)Nc2cnn(Cc3cccc(F)c3)c2)c1 +COC(=O)C1=C(N)Oc2cc(C)oc(=O)c2C1c1cccc(OC)c1 +Cc1cccc(C(=O)Nn2c(C)nc3sccc3c2=O)c1C +Cc1ccccc1NC(=O)NC1CCN(c2ccccc2)C1=O +COc1cccc(OC)c1COC(=O)c1cc(C#N)cn1C +CC(=O)NC(C)c1nc2ccccc2n1C(C)C(C)=O +CCc1noc(C)c1C(=O)OC(C(=O)Nc1cc(C)on1)C(C)C +O=C(NCCCN1CCCC1=O)NCc1csc2ccccc12 +N#Cc1cnc(SCC(=O)NCc2ccc(F)cc2)nc1N +O=C(Nc1ccc(F)cc1)Nc1ccc(N2CCNC2=O)cc1 +N#Cc1ccccc1NC(=O)CCn1cc(Br)ccc1=O +COC(=O)C(O)(c1ccc(O)c(Br)c1)C(F)(F)F +Cn1cccc1C(=O)N(CCC#N)Cc1ccco1 +Cc1occc1C(=O)N(C)CC(=O)Nc1ccc(Cl)c(Cl)c1 +Cc1nc(NC(=O)c2cn3c(C)cccc3n2)sc1-c1ccccn1 +Cc1nc(CC(=O)N(C)Cc2ccsc2)cs1 +O=C(CO)N1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +CC(C)NC(=O)CCOc1cccc(Br)c1 +Cc1csc(C(C)NC(=O)Nc2nnc(C(F)(F)F)s2)n1 +CS(=O)(=O)c1ccc(-c2cc(O)cc(Br)c2)cc1 +NC(=O)c1ccc(NC(=O)CCSc2ccccc2)cc1 +Cc1ccc(-c2cc(C(=O)N(C)c3nccs3)on2)cc1 +CC(Cc1ccco1)NC(=O)c1cn2cccnc2n1 +COC(=O)c1cccc(S(=O)(=O)Oc2cc(C)ccc2C(C)=O)c1 +Cc1nc(C(C)Nc2ccnc(C(F)(F)F)n2)n[nH]1 +CCCNC(=O)Cn1nc(C)c2nn(-c3ccccc3)c(C)c2c1=O +COc1ccc(CNC(=O)CCc2nc(-c3cccnc3)no2)cc1 +COCCCn1cnnc1SC(C)C(F)(F)F +COCC(=O)NC(c1ccc(Cl)cc1)c1nccn1C +CCC(C)c1ccccc1N1CC(C(=O)NC(C)COC)CC1=O +COc1cccc(OCC(=O)NCC#Cc2ccccc2N(C)C)c1 +CNC(=O)c1cc(S(=O)(=O)Nc2ccc(C)cc2C)ccc1OC +COC(=O)CCSc1nnc(-c2cccs2)n1C +CC(Oc1ccc(Cl)cc1Cl)c1c(CO)nnn1C +Cc1ccc(SCc2cc(N)cc3c2OCOC3)cc1 +CCCNC(=O)CN(C)C(=O)CCn1c(=O)[nH]c(=O)c2ccccc21 +Cn1ccnc(NC(=O)COc2ccc(Cl)c(Cl)c2)c1=O +CC1CC(c2ccc(F)cc2)CN1C(=O)Cc1ccc[nH]1 +C=CCCc1nnc(C(N)c2cc(C#N)ccc2F)o1 +C(=Cc1nn2c(C3CC3)nnc2s1)c1cccnc1 +O=C(NCc1cccc2ccccc12)c1scnc1C1CC1 +COc1cc2c(cc1F)C(c1ccc(C#N)cc1)NCC2 +Fc1cccc(Oc2nnnn2-c2ccccc2)c1 +CCC(C)NC(=O)C1CCCN(C(=O)Nc2cccs2)C1 +CN(C(=O)c1cc2n(n1)Cc1ccccc1NC2=O)c1ccccc1 +c1ccc2oc(-c3csc(NC4CC4)n3)cc2c1 +CC(C)(C)C(=O)NCC(=O)Nc1ccc(CN2CCOCC2)cc1 +Cc1ncccc1C1NCCc2c(Cl)cccc21 +Cc1ncsc1C(=O)NCC(O)COCc1ccccc1 +COc1cc(CO)ccc1OCCc1ccccc1 +Cc1ccc(OCC(=O)C(C#N)c2nc3ccccc3[nH]2)c(C)c1 +Nc1ncccc1C1NCCc2cc(F)cc(Cl)c21 +COc1ncccc1C(=O)Nc1ncc(C#N)s1 +Cc1c(NC(=O)c2ccc(-c3ccccc3)[nH]c2=O)cccc1C(N)=O +O=C(CCCCN1CCOCC1)Nc1ccc(Br)cc1 +COCc1ccc(C(=O)NC(C(=O)OC)c2ccccc2)cc1 +O=C1CN(C(=O)NCC2(c3ccc(F)cc3)CCCC2)CCN1 +O=C(NCc1ccc(-c2nc3ccccc3[nH]2)cc1)C1CC2CCC1O2 +CNc1snc(C)c1C(=O)OC(C)c1nc2ccccc2c(=O)[nH]1 +CC(NC(=O)c1ccccc1Cl)C(=O)N1CCCCC1 +CCOCc1cccc(CNC(=O)c2ccsc2)c1 +COc1ccc(-c2cnn3c(N)c4c(nc23)CCC4)cc1 +CSc1ccc(C)c(C(=O)N2CCC(Oc3ccccc3)CC2)c1 +COc1cc(C)ccc1OCc1ccc(S(=O)(=O)C(F)F)cc1 +COC(=O)c1cnc(NC(=O)CCc2cccc(F)c2F)s1 +Cc1nc(C)c(C(=O)OCC(=O)N(C)C2(C#N)CCCCC2)s1 +CCC(NC(=O)c1cc(OCC(=O)N(C)C)n(C)n1)c1ccccc1 +CN1C(=O)COc2ccc(S(=O)(=O)N(C)CCO)cc21 +CCN(CC1COc2ccccc2O1)C(=O)c1cc(C2CC2)[nH]n1 +CCn1c(C(C)NC(=O)c2cccc(OC)c2F)nc2ccccc21 +CC(=O)Nc1ccc(OC(=O)c2ccnc(OC3CCC3)c2)cc1 +O=C(Nc1ccc2c(c1)COC2)N1CCN(c2ccc(O)cc2)CC1 +Cc1nn(-c2ccccc2)cc1CNc1cnn(CC(C)C)c1 +Cc1noc(COC(=O)c2ccc(-n3cncn3)cc2)n1 +Cc1ccc(S(=O)(=O)CSc2nccc(O)n2)cc1 +Cc1cn2c(CCC(=O)N3CCCCC3C3OCCO3)csc2n1 +COCCC(C)C(=O)Nc1nn(-c2ccccc2Cl)cc1C +C=CCOC(C)C(=O)Nc1ccc(NC(=O)NC)cc1 +Cc1ccc(OC(=O)c2c(C)nn3c(C)cc(C)nc23)cc1 +Nc1nc2n(n1)CCC(c1cc(F)cc(F)c1)C2 +COCCOc1ccc(NC(=O)C2COc3ccccc3O2)cn1 +O=C1CC(c2cc(F)ccc2F)c2cnn(-c3ccc(F)cc3)c2N1 +O=C(Cc1cccs1)NC1CCN(c2ncccn2)CC1 +CN(C)C(=O)COc1ccccc1CNc1cccc(F)c1 +CC1CN(c2nc3c(c(=O)[nH]c(=O)n3C)n2C)CCO1 +CC(C)OC(=O)c1nnn(-c2ccc(C(C)C)cc2)c1N +CC(=O)Nc1ccc(F)c(C(=O)NCCCC(N)=O)c1 +CCc1nc(CNc2cc(Cl)ccc2C(=O)N(C)C)no1 +COC(=O)CCNC(=O)c1cc(F)ccc1NC(=O)N1CCCC1 +CCN(CC(C)C#N)C(=O)c1c(C)noc1C(C)C +N#CCc1nc2c(s1)CCOc1ccc(Cl)cc1-2 +CCCC1CN(c2nccnc2C)CC1NC(=O)C1(COC)CC1 +CC(c1ccccc1)N1CC(C(=O)NC2(C#N)CCCCC2)CC1=O +O=C(c1[nH]nc(C2CC2)c1Br)N1CCCC1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1cccnc1SC(F)F +CC(=O)N1CCN(Cc2nn3c(=O)cc(C)nc3s2)CC1 +COc1ccc(O)c2c1C(Cc1cccnc1)NCC2 +Cc1cccc(C(=O)c2ccc(Br)cc2)n1 +CCCOC1CCCN(C(=O)c2ccc(S(N)(=O)=O)cc2)C1 +Cc1nc(NC(=O)NCc2ccccc2-n2ccnc2)nn1C(C)C +Cc1cc(C)c(NC(=O)CCN2C(=O)COc3ccccc32)c(C)n1 +COc1ccc(CCN2CCN(C(=O)c3csnc3C)CC2)cc1 +O=C(NCC1CCC1)c1cc(-c2ccc(F)cc2)on1 +O=C(NCC(=O)N1CCNCC1)c1ccsc1 +Cc1ccc2c(=O)c(C(=O)N3CCC(C)CC3)c[nH]c2n1 +CCOC(=O)N(C)CCOc1ccc(Cl)cc1 +CC(=O)c1ccc(NC(=O)C2CCCN(C(=O)C(C)(C)C)C2)cc1C +O=C(CSc1c(Cl)cccc1Cl)NCc1cccnc1 +COc1ccc(C(C)C(=O)OC2CCCC2OC)cc1 +COc1cc(C(C)Nc2ccc(F)cc2)ccc1O +Cc1ccoc1C(=O)Nc1ccc(NC(=O)OC(C)(C)C)nc1 +O=C(NCCc1cccs1)c1cnc2[nH]ccc2c1 +COc1ccc(O)c(C(=O)N(C)Cc2ccc(OC(F)F)cc2)c1 +CCCCn1nc(C(=O)NCCc2cccc(Cl)c2)ccc1=O +COc1cc(OC)c(C(N)C(F)(F)F)c(OC)c1 +CCC(c1nc2c3cnn(C)c3ncn2n1)n1cc(Cl)cn1 +Oc1cccc(C2CN(Cc3ccc(Cl)c(F)c3)CCO2)c1 +Cc1ccc(-c2nc(CC(=O)Nc3ncc(C)s3)cs2)o1 +Cc1ccccc1NC(=O)Cn1cnc2nc3c(cc2c1=O)CCCC3 +CCc1cccc(C)c1NC(=O)Cn1cnc2sc(C)cc2c1=O +COc1cccc(NC(=O)Cn2nnc3c(C)n(C)nc3c2=O)c1 +O=C(NCc1ccccn1)c1cccc(Br)c1 +COC(=O)c1nn(-c2ccccn2)c(C)c1Br +CCCc1cc(NC(=O)C(C)NC(=O)c2cccc(C)c2)n[nH]1 +CC1CCCN(C(=O)CCNC(=O)c2ccc[nH]c2=O)C1 +CCNC(=O)C(C)Oc1cc2c(cc1CO)OCO2 +CC(Sc1ccccn1)C(=O)NC1(C#N)CCCCC1 +Cc1cc(NC(=O)Cc2ccc[nH]2)ccc1OC1CCOCC1 +CC1COc2ccc(C(=O)C3CC3)cc2N(C)C1=O +CC(C)COC(=O)Nc1cccc(NC(=O)c2ccncc2F)c1 +Cc1ccc(C(=O)NC(C#N)c2cccs2)cc1C +CC1CN(C2CCN(c3cncc(Br)c3)CC2)CCO1 +CC(C)c1cc(CNC(=O)c2cccc(-c3ccoc3)c2)on1 +CCCCCn1cc(C(=O)N(C)C)c(=O)c2c(N)cccc21 +Cc1ccoc1CNc1nnc(Cc2ccc(F)cc2)o1 +COC(=O)c1ccc(C(=O)NC(C)c2ccc(C)s2)s1 +COc1ccccc1N1CCN(c2ncnc3c2cnn3C)CC1 +COc1cccc(CNC(=O)CS(=O)(=O)c2ccc(C)c(C)c2)c1 +Cc1c(C(=O)N2CCCC(n3cccn3)C2)oc2ccccc12 +C=CCNC(=O)CSc1nc2ccc(OCC)cc2[nH]1 +Cc1nnc(-c2cccc(-c3cccc(N)c3)c2)o1 +O=C(Nc1ccccc1)Nc1nnc(C2CCCCC2)s1 +NC(=O)c1cnc(NCC(c2ccc(Cl)cc2)n2cccn2)cn1 +COc1ccc(C(=O)NC2CCCOc3ccccc32)nn1 +CC(Sc1nccn1Cc1ccccn1)C(=O)NC1CC1 +OC1CN(c2noc(C3CC3)n2)CCC1c1ccc2c(c1)OCO2 +CC(C(=O)NCCOc1cccc(Cl)c1Cl)n1cncn1 +CCC(C)c1noc(C2CCN(C(=O)c3ccc(Cl)cc3)CC2)n1 +CC(=O)Nc1ccc(C(=O)OCC(=O)C(C)(C)C)cc1 +CC(C)(C)c1ccc(-n2nnc(CO)c2-c2cccnc2)cc1 +Cc1ccc(F)cc1S(=O)(=O)N(CCC#N)CCC(F)(F)F +COc1ccc(C(O)CCC(=O)NC(C)c2ccccc2)cc1 +CCc1nc2ccccc2n1CC(=O)Nc1ccc2c(c1)CCC2 +CCCn1nc(C(=O)N(C)Cc2ccc(C(N)=O)cc2)ccc1=O +CS(=O)(=O)c1ccccc1Oc1cccc(N)c1 +CCOC(=O)C(C)NC(=O)c1c(C)nn(C)c1C +COc1c(Br)cccc1CNC(=O)Cc1ccc[nH]1 +Cc1nn(C)cc1CNCCc1c[nH]c2ccc(F)cc12 +Cc1nc(C)c(CC(=O)NCCc2csc(C)n2)c(=O)[nH]1 +Cc1ccc(OC(C)C(=O)NC(C)(C#N)C(C)C)cc1 +Cc1ccc(C(=O)CNC(=O)CCOc2ccccc2)c(C)c1 +O=C(Nc1ccc(N2CCCC2)nc1)c1scnc1C1CC1 +CN(Cc1ccc(C(=O)NC2CC2)cc1)c1nc2ccccc2o1 +Cc1nn(C)c(C)c1NCC(C)(C)c1ccccc1 +CC(=O)c1cc(C#N)c(N(C)Cc2ccccc2)nc1C +NC(=O)c1c(NC(=O)NCc2cccnc2)sc2c1CCCC2 +C#CCN1CCN(CC(=O)N(C2CC2)C(C)C2CC2)CC1 +O=S(=O)(NC1CCN(c2c(F)cccc2F)C1)c1cccs1 +CC(C)N(C(=O)c1cnn(-c2ccccc2F)c1)C1CCC1 +C#CCNc1ccc(C(=O)Nc2ccccc2)cc1 +Cn1nc(C(=O)NCc2ccc(Cl)cc2Cl)ccc1=O +CC1(C(=O)NCc2ccccc2)CCC(=O)N1CCC1=CCCCC1 +COCCOc1cccc(CNC(=O)c2cnc3ccc(C)cn23)c1 +O=C(Nc1nc2c(s1)CN(C(=O)CC1CCCC1)CC2)C1CC1 +O=C(Cn1cc(-c2ccccc2)nn1)N1CCc2cc(F)ccc2C1 +O=C(Cn1ccc2ccc(Cl)cc21)NCCc1ccccn1 +O=S(=O)(NCc1ccco1)c1ccc(Cl)cc1Cl +CN(C(=O)c1ccccc1NC(=O)c1cnccn1)C1CCCCC1 +Cc1cc(OCC(=O)N2CCC(=O)CC2)cc(C)c1Cl +Cc1ccc(C(C)NC(=O)C2CCC(C(N)=O)CC2)cc1F +COc1cc(C(C)=O)ccc1OC(=O)COc1ccc(Cl)cc1 +COCCNC(=O)c1ccc2c(c1)C(=O)c1cnccc1-2 +Cc1ccc(NC(=O)c2cc(S(=O)(=O)N3CCCC3)cn2C)nc1 +Cn1cccc1CCC(=O)N1CCC2(CC1)c1ccccc1CC2O +O=C(CNC(=O)Cc1ccccc1)NCc1ccc2c(c1)OCCO2 +CN(Cc1cnn(C)c1)S(=O)(=O)c1ccccc1-c1ccccc1 +O=C(c1ccc(O)cc1)N1CCN(c2ncnc3c2CCC3)CC1 +O=S(=O)(Oc1cccnc1)c1ccc(Cl)cc1 +CC(C)c1nc(N2CC3c4ccccc4OCC3(CO)C2)no1 +O=C(NCCc1ccccc1Cl)c1cncc(Br)c1 +COC(=O)C(c1ccc(Cl)c(Cl)c1)N(C)C(=O)C1CCOC1 +Cc1nc(CNC(=O)c2sccc2C#N)c(C)s1 +CC(C)(C)NC(=O)CCS(=O)(=O)c1ccccc1 +O=C1CSc2ccc(NCc3ccccc3-n3cccn3)cc2N1 +COc1cc2nc(-c3cccc4c3OCC4)nc(N)c2cc1OC +CCCCN(C)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +CC(C)N1CCC(N2CCN(Cc3nccn3C(F)F)CC2)C1=O +CN(C)C(=O)C1CCN(C(=O)NCc2ccc(F)c(Cl)c2)CC1 +COc1ccc(Cl)cc1NCc1noc(C(C)C)n1 +Cn1c(SCC(=O)C2=NC=CC2)nnc1-c1ccccc1 +CCCCCC(C)Nc1nn(C)c(=O)n(C)c1=O +COc1cccc(C2CC(c3cccc(C)c3)n3nc(N)nc3N2)c1 +COCC1c2c(cnn2C)CCN1Cc1ccc(F)cc1 +O=C(C1COc2ccccc2O1)N1CCC(Cc2ccccc2)CC1 +OC(CNc1ccccc1F)COc1ccccc1F +COc1ccccc1NC(=O)CCc1nc2ccccc2s1 +Cc1nc(C2COCCN2C(=O)c2cc(Cl)cc(Cl)c2)no1 +CCC(O)c1c(C)nn(CC2CCOCC2)c1C +COC(=O)CCC(=O)Nc1ccccc1-n1nc(C)cc1C +Cc1cc(C(=O)CN2CCN(c3ccccc3Cl)CC2)c(C)n1C +N#Cc1nnn(-c2cccc(C(F)(F)F)c2)c1C(F)(F)F +Cc1csc(CN(C)c2nncc(-c3ccc4c(c3)OCO4)n2)n1 +CC(=O)Nc1ccc(SCC(=O)Nn2cnc3ccccc32)cc1 +Cc1cc(C)c(C(=O)NCCc2ccc(C)s2)c(=O)[nH]1 +COCCCCNc1ccc(-n2cnnn2)c(C)c1 +COC(=O)C(Cc1ccccc1)NC(=O)N1CCC(C)CC1 +O=C(NCC1CCCCO1)c1cncc(Br)c1 +Cc1cc(C(=O)N2CCC3(CCCN(C)C3=O)C2)c(C)o1 +CC1(C)Cc2nc3oc4c(N5CCOCC5)ncnc4c3cc2CO1 +CCN(CC1COc2ccccc2O1)c1ncnc2sccc12 +C=CCNC(=O)c1cccnc1-c1ccc(OC)c2ncccc12 +C#CCN1CCN(C(=O)Nc2ccccc2F)CC1 +Cc1nc(NC2CC2)sc1C(=O)NCc1cccnc1 +COC1CCCN(C(=O)c2cc3cccc(Br)c3o2)C1 +COc1ccc2c(c1)CC(NC(=O)NCc1ccccn1)CO2 +O=C(CCC1CCCC1)N1CCN(C(=O)c2cccnc2)CC1 +N#CC1CCCC1NS(=O)(=O)N1CCCCC1 +COC(=O)C(C)CN(C)C(=O)c1cccn1C(C)C +CC(C)CC(=O)Nc1ccc(NS(C)(=O)=O)cc1 +COc1cccc(C(=O)N2CCC(C)CC2C)c1O +COCCN1C(=O)CC2C1CCN2C(=O)c1ccsc1 +COc1cccc(-c2nc3c(F)cccn3c2CO)c1 +COCC(C)OC(=O)c1nn(-c2ccc(F)c(F)c2)c2c1CCC2 +Cc1ccc(C(C)CNC(=O)c2cc(S(N)(=O)=O)oc2C)cc1 +CCc1ccsc1C(=O)NC1CCC(C(=O)NC)CC1 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)N1CCN(c2cnccn2)CC1 +Nc1ccccc1NC(=O)CCCN1CCOCC1 +CCCSc1nc2c(c(=O)[nH]c(=O)n2C)n1C +CCCOc1cc(-c2nnc3ccccn23)ccc1N +O=C(c1cscn1)N1CCC2C1CCC(=O)N2c1ccccc1 +O=C(Cc1ccc2c(c1)OCO2)Nc1nc(-c2cccs2)cs1 +Cc1cc(NS(=O)(=O)c2ccccc2)c(C)cc1N +Cc1ccccc1C(=O)Nc1nc(-c2c[nH]c(C(N)=O)c2)cs1 +C=CCC1(CO)CCCN(C(=O)c2cncc(Cl)c2)C1 +CCC(C)NC(=O)C1CCC(=O)N(C)C1c1cccs1 +CCCCc1c(CO)nnn1CC(=O)Nc1nnc(C)s1 +O=C(Cn1cc(-c2nnco2)ccc1=O)Nc1cc(Cl)ccc1F +CCN1C(Cl)=Nc2c(ccc(C)c2C)S1(=O)=O +Cc1ccc(OC2CCN(C(=O)c3ccc(=O)[nH]c3)CC2)cn1 +CCCN(CC(=O)OCC)C(=O)c1cc(N)cn1C +O=C(c1ncccc1Cl)N1CCc2ccccc2C1 +Cc1nnc(SCC(=O)N(C)CC(=O)NC2CC2)s1 +COc1ccc(C(NC(=O)C2CC2)C2CCOCC2)cc1 +CC(C)N(C)S(=O)(=O)NCc1cccc(O)c1 +COc1c(F)cc(NC(=O)N2CCC(C)CC2)cc1F +Cc1ccc(NC(=O)c2ccccc2-n2cnnn2)cc1F +COc1ncccc1CNC(=O)Nc1ccc(CC(=O)N(C)C)cc1 +O=C(CCCn1cccc1)Nc1ccc(Oc2cccnc2)nc1 +CCCCCN1C(=O)C(C)Oc2c(OC)cc(CO)cc21 +CN(CC(=O)NCc1ccoc1)C(=O)c1ccco1 +O=C(CCc1nc(-c2cccnc2)no1)NCc1ccc(F)cc1F +COc1cc(OC)c(OC)cc1CNC(=O)c1ccc(C)s1 +O=C1Oc2c(ccc3ccccc23)C1(O)C(F)(F)F +CCC(C)(C)NC(=O)CSc1nnc(-c2ccoc2C)o1 +Cc1csc(N2CCCN(C(=O)NCCC(C)C)CC2)n1 +COc1cc(OC)cc(C(=O)OC(C)C(N)=O)c1 +c1cnc(-n2cc(NCc3csc(C4CC4)n3)cn2)nc1 +Nc1cc(C2CCN(C(=O)Nc3ccc(F)cc3F)CC2)no1 +N#Cc1cc(NC(=O)NCCCO)ccc1OCC(F)(F)F +O=C(Nc1ccnn1C1CCCC1)c1ccc(N2CCCC2=O)cc1 +CCCCNC(=O)c1ccc(-n2ncc(C(=O)OC)c2N)cc1 +Cc1ccc2c(CC(=O)N(C)CCC#N)coc2c1C +Cc1cc(CNc2cccc(C(C)O)c2)ccc1O +CC(C)C(C)N(C(=O)NCCCn1nc2n(c1=O)CCCC2)C1CC1 +Cc1cccc2[nH]c(CCN(C)C(=O)CN3CCOC3=O)nc12 +CC(C)CNC(=O)CCCc1c[nH]c2ccccc12 +CCN1CCN(C(=O)CC(c2ccccc2)c2ccccc2)CC1 +Cc1noc(NC(=O)CCc2c(C)c3c(C)nn(C)c3[nH]c2=O)n1 +CCC(NC(=O)NCC(=O)NCC(C)C)c1nc(C)cs1 +O=C(NCc1ccc2c(c1)OCO2)c1ccc(-n2cnnn2)cc1 +CCCNC(=O)c1cc(F)cc(Br)c1 +c1cncc(CCc2nc(C3CC3)nn2-c2cccc3cccnc23)c1 +Cc1ccc(-c2nc(CNc3ccc(S(C)=O)c(F)c3)co2)cc1 +COC(=O)CC1Oc2ccc(Cl)cc2NC1=O +CCC(=O)N1CCCC(c2nc(-c3cccc(Cl)c3)no2)C1 +CN(C)C(=O)CN(C)C(=O)C1CCN(CC(F)(F)F)CC1 +Cc1ccc(-c2nc(C)ncc2C)c(-n2cccn2)c1 +CCc1c(C)nn(CCNC(=O)c2ccc3cccc(F)c3n2)c1C +Nc1ccc(-c2noc(-c3cccc(Cl)c3)n2)cc1 +CCC(CC)NC(=O)C(C)S(=O)(=O)c1cccc(C)c1 +Cc1ccccc1CCNC(=O)Cn1cnc2ccccc21 +CSc1ncccc1C(=O)OCc1cc(=O)n2cc(C)ccc2n1 +CCNC(=O)c1cc(-c2ccc(Cl)cc2)nc(N)n1 +Clc1cccc(Cl)c1C(Nc1ncccn1)Nc1ncccn1 +Cc1nc(N2CCCC2=O)sc1C(=O)Nc1ccc(F)c(F)c1 +CCc1nc2ccc(C(=O)Nc3nnc(C)s3)cc2nc1CC +Oc1ccc(C2Oc3cc(O)cc(O)c3CC2O)cc1 +Cc1ccc(C(=O)N2CCCC2CN2CC(C)OC(C)C2)cc1 +CC(=O)N1CCC(N(C(=O)CCC(F)(F)F)c2ccccc2)CC1 +COC(=O)C(C)(C)NC(=O)CNC(=O)CNC(C)=O +Cc1noc(C)c1CCCNC(=O)NC1CCCC(C)C1C +Nc1nc(N)nc(COC(=O)C2(c3cccc(F)c3)CCCC2)n1 +O=C(CCCc1cccs1)Nc1cccc(F)c1 +CCOc1ccccc1NS(=O)(=O)c1ccc(OC)cc1OC +CN(C)c1c(OC2CC2)ccnc1OC(C)(C)C +O=C(c1ccc2[nH]cnc2c1)N1CCOC(c2ccc(Cl)cc2)C1 +Cc1nc(C)c(C(C)N(C)C(=O)C2CCCN(C(=O)C3CC3)C2)s1 +O=C(Cc1cccc(Cl)c1)NCc1ccnc(OC2CCC2)c1 +COC(=O)CCCCNC(=O)Nc1cccnc1 +COc1ccc(C#N)cc1NCc1ccc(-n2nc(C)cc2C)cc1 +Cc1cc(F)ccc1NC(=O)c1cn(C)c2ncccc12 +CCC(C)n1ncc(C(=O)Nc2cc(C)n[nH]2)c1C1CC1 +c1cc2c(s1)CCN(Cc1nnc(C3CCCO3)o1)C2 +COc1cccc(CCC(=O)NCC2(C(N)=O)CCOCC2)c1 +Cc1cccc(NCC(=O)N(C)C2CCC(C)CC2)c1C(N)=O +Cc1nn(CC(=O)NC2CC2)c(=O)c2cc3sccc3n12 +Cc1cnc(C(=O)N2CCC(c3nnc4n3CCC4)CC2)cn1 +CC(=O)NC(CC(=O)Oc1ccc2cn[nH]c2c1)c1ccccc1 +CCCCCNC(=O)C(N)c1ccc(O)c(F)c1 +COc1ccc(NC(=O)c2cccc(-n3cnnn3)c2)c(OC)c1 +CCC1CN(CC(=O)c2cccs2)c2c(N)cccc2O1 +COCCC(C)NC(=O)NC1CCC(Oc2ccc(C#N)cn2)CC1 +CS(=O)(=O)c1ccccc1C(=O)Oc1ccc(-c2nnco2)cc1 +Nc1c(Cl)cc(NC(=O)c2csnn2)cc1Cl +COc1cc2c(cc1C)CCNC2C(C)NC(C)=O +CN(CC(=O)c1c(N)n(C2CC2)c(=O)[nH]c1=O)c1ccc(F)cc1 +CCN(CCO)C(=O)NCc1ccc(-c2cccnc2)cc1 +CC(NC(=O)c1cc(C(C)(C)C)n[nH]1)c1ccc(-n2ccnc2)cc1 +COC(=O)c1nn(-c2ccccn2)c(C(C)C)c1Br +Cc1csc(C(=O)NCc2cc(-c3cccs3)n(C)n2)c1 +O=C(c1cc(F)c(F)cc1Cl)N1CCN(Cc2ccco2)CC1 +CN(CCN1CCOCC1)c1cc(Br)c2nonc2c1 +C#CCN1CCN(CC(=O)N(C)C(C)c2ccccc2)CC1 +CCN(Cc1nonc1C)C(=O)Cc1ccc(-n2cnnn2)cc1 +CC1CCC(C(N)=O)CN1c1ccc2nnc(C(F)(F)F)n2n1 +Cc1ccc(-n2nc(CO)cc2C)c(Br)c1 +CCC(OC1CCCCC1)C(=O)N1CCC(O)(C(F)(F)F)CC1 +Cc1nsc(C)c1NC(=O)CNC(=O)c1cc2ccccn2n1 +Cc1ccc(C)c2sc(N(C)CC(=O)NCC3CCCO3)nc12 +COC1CCCC1OC(=O)c1ccc(OCC(F)(F)F)nc1 +O=C(CN1CCN(C(=O)c2scnc2C2CC2)CC1)N1CCCC1 +CCNc1nc2ccc(N3CCN(C(=O)CC)CC3)cc2s1 +Cc1cc(C(=O)NC2CCCN(c3ccccc3F)C2=O)[nH]n1 +CCN1CC(C(=O)Nc2ccccc2COc2ccccc2)CC1=O +O=C1Nc2ccccc2Nc2nc(-c3cccnc3)ccc21 +Cc1ccncc1NC(=O)N1CCOCC1CC(C)C +Oc1ccc(O)c(-c2ccnc3cc(-c4ccc(F)cc4)nn23)c1 +CC(C)(CNC(=O)c1ccc(C#N)cn1)c1ccncc1 +CCOc1ccc2c(c1)CN(C(=O)NCc1nccs1)CC2 +CCOCCN(CC)Cc1cnc2c(C)cccn12 +CCCc1cc(C(=O)OCCc2cccs2)[nH]n1 +COc1nc(C(=O)N(CC(N)=O)C2CCCC2)cc2ccccc12 +Cc1nnc2n1CC(NC(=O)Cc1ccc3c(c1)OCCO3)CC2 +Cc1cc(F)ccc1CN1CCN(Cc2nccn2C(F)F)CC1 +CC1CC(=O)Nc2ccccc2N1C(=O)c1ccc(C#N)cn1 +CN(C)c1nc(Cn2cc(CNC(=O)OC(C)(C)C)cn2)ns1 +C#CCOc1cccc(NC(=O)CCNC(=O)C(C)(C)C)c1 +OCc1cccc(NCc2cc(Cl)ccc2F)c1 +CCN(Cc1ccccc1Cl)C(=O)c1ccc(F)cc1 +Cc1nc(C)c(CC(=O)N2CCCN(c3ccccc3C)CC2)s1 +C=CCOc1ccc(C(=O)N(C)CC2CCCC2)cc1 +COc1ccc(CNc2ccc(C)c(NC(C)=O)c2)c(OC)c1 +COC(=O)c1ccc(CS(=O)(=O)NC(C)CO)cc1 +COCc1cn(C2CCN(C(=O)Nc3ccsc3)CC2)nn1 +NC(=O)c1ccc(-c2nnn(CCc3ccccc3)n2)cc1 +O=c1[nH]c(C=Cc2ccc3c(c2)OCO3)nc2ccccc12 +Cc1nc(CN(CCC#N)CC(C)(C)C)cs1 +Cc1nc(C)nc(CCc2cccc(Br)c2)n1 +COC(=O)N1CCN(C(=O)c2cccc(Cl)c2Cl)CC1 +Cc1nc(SCCCc2nc3ccccc3o2)sc1CC(N)=O +NS(=O)(=O)NCC1CCCN(C(=O)c2ccccc2Cl)C1 +CC(C)CCC(=O)NC1CCSc2c(F)cccc21 +Cc1noc(C)c1Cn1nnc(CO)c1COc1ccccc1 +Cc1ccc(N2CCCC(Nc3ccc4c(c3)CC(=O)N4)C2=O)cc1 +CCCNC(=O)Cc1cc(Cl)c2c(c1)OCCO2 +CS(=O)(=O)c1ccc(CNc2cccc(F)c2C#N)cc1 +COc1c2ccc(C(=O)NCc3ccc(F)cc3F)cc2nn1C +COC1CCCC1OC(=O)CCc1nc(-c2ccc(C)c(F)c2)no1 +Cc1cc(C(=O)N2CC=CC2CO)c2cccc(C)c2n1 +CCc1cc(C(=O)NCCC(C)C)nc2cc(-c3ccco3)nn12 +Cc1cccc(NCc2c(F)cccc2Cl)c1C(N)=O +CC(C)NC(=O)N1CC(c2nc(-c3ccccc3)no2)C1 +Cc1ccc(SC2CC(=O)C3OCC2O3)cc1 +CCN(C(=O)CNc1cccc(C(N)=O)c1C)c1ccccc1 +CCN(Cc1ccoc1)C(=O)Cc1c[nH]c2c(C)cccc12 +CCN(CC)c1nc2sc(C(=O)N(C)C3CC3)cc2s1 +OCCCn1cnc(-c2ccccc2)c1-c1cnc2ccccc2c1 +COc1ccc(NC(=O)C2CCCN2C(=O)C(C)C)c(Cl)c1 +CC(C)(C)c1ccc(C(O)CNC(=O)C2CC2)cc1 +COc1ccccc1OCCNc1ncnc2ccccc12 +COc1c(Cl)cc(C(=O)N2CC(O)C2)cc1Cl +CN(CCn1cccn1)C(=O)c1ccc2[nH]c(C(F)(F)F)nc2c1 +COc1c[nH]c(C(=O)N2CCOC(CCc3ccccc3)C2)cc1=O +CCOC(=O)C1CCCC(=O)N1c1cccc(Cl)c1C +CC1CC1C(=O)Nc1ccc(C(=O)NC2CCOCC2)cc1 +CN(Cc1ccc(F)cc1F)C(=O)c1ccc2c(c1)COCO2 +COC(=O)c1ccccc1Cn1ccnc1Cc1cccs1 +CCOc1c(Cl)cccc1NC(=O)N(C)Cc1nnc2n1CCC2 +CC(OCC1OC(n2cnc3c(N)ncnc32)C(O)C1O)C(N)=O +O=C1CCC(COC(=O)CC2CC3CCC2C3)N1 +Cn1c(CN2CCN(CC(=O)c3ccccc3)CC2)nc2ccccc21 +CCCNC(=O)CCNC(=O)c1cc2ccccc2oc1=O +Cc1n[nH]c(SCc2ccc(F)cc2Br)n1 +COCCNC(=O)Cn1nnc(C(C)=O)c1-c1ccccc1 +COC(=O)c1cc(C)nc(N2CCN(C(C)=O)CC2)n1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)Nc1ccccn1 +CCCNC(=O)c1nnn(-c2ccc(C)cc2)c1-c1cccnc1 +CN1C(=O)CCOc2ccc(-c3cc(=O)[nH]c(N)n3)cc21 +Cc1ccccc1CNc1ccccc1NC(=O)C1CCC(=O)N1 +O=C(Cc1ccc(F)c(F)c1)Nc1ccc(N2CCOCC2)cn1 +CCC1CCCCN1c1ccc(S(C)(=O)=O)cc1N +CC1=NC(=O)C(CC(=O)NC(C)Cc2cccc(Cl)c2)C(C)=N1 +COc1ccccc1CCN(C)C(=O)c1ccc(N)cc1 +O=C(Cn1cncn1)N1CCC(c2ccc3c(c2)OCO3)C(O)C1 +CCc1nnc2n1CC(NC(=O)c1cc3ccccc3o1)CC2 +N#CC1(NC(=O)CN2CCc3ccccc32)CCCC1 +CC(Sc1nc2ccccc2[nH]1)C(=O)Nc1ccc(C#N)cc1 +CCC(C(=O)Nc1cc(C)on1)N1CCn2c(nnc2C2CC2)C1 +Fc1cccnc1N1CCCC2(CN(Cc3ccncc3)CCO2)C1 +CCC(=O)N1CCN(C(=O)c2nc3c(F)cccc3s2)CC1 +CCOC(=O)CSc1ncc(Br)cn1 +Cc1nn(C)cc1NCc1cc(C(F)(F)F)nn1C +CCn1nc(C)c(CNC(=O)N(C2CC2)C(C)c2ccco2)c1C +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(Cl)c(C)c2)cc1 +Clc1cccc(CNc2ncnc3ccsc23)c1 +COc1ccnc(N2CC3CCC(C2)N(CC2CCC2)C3=O)n1 +O=C(c1ccoc1)N1CCN(Cc2nc(-c3cccs3)no2)CC1 +NC(=O)CCCCSc1ncnc2c1cnn2-c1ccccc1 +CS(=O)(=O)NCC(=O)NCc1cn2cc(Cl)ccc2n1 +O=C(NCC(O)C1CC1)c1cccc(Cl)c1Cl +COc1cc(C)cc(CNC(=O)NCC(C)(C)OC)c1 +Cc1ccccc1C1CCCN(C(=O)c2cnoc2C)C1 +Cc1ccc[nH]c1=NS(=O)(=O)c1ccc(Cl)cc1F +Cc1ccccc1Cc1cnc(NC(=O)c2ccc3nncn3c2)s1 +Cc1ccc(NC2=Nc3cc(N)ccc3OC2C)cc1 +COc1ccc(C2NCCc3cc(F)c(C)cc32)cc1O +COC(C)C(=O)NCc1noc(-c2ccsc2)n1 +Cc1csc(CN(C)Cc2ccc(F)c(C(F)(F)F)c2)n1 +CCC1CN(C(=O)CN2C(=O)CCc3ccccc32)CC1O +O=C(Nn1cnc2ccccc21)c1csc(-c2ncccn2)n1 +Fc1ccc(-n2nc(C3CC3)c3c2CCNC3)cc1F +CCNC(=O)CNC(=O)c1cc(C(C)C)nn1CC +COc1ccc(C(=O)N2CCCCC2c2cn[nH]c2)c(F)c1 +Cc1ccc(NC(=O)C(C)n2nnc(-c3ccccc3)n2)c(F)c1 +Cc1ccc(OCC(=O)N(Cc2ccsc2)C2CC2)cc1 +CCCCCOCC(=O)N=c1[nH]nc2cc(C)ccn12 +Cc1ccccc1NC(=O)C(C)Oc1cccc2ccc(=O)[nH]c12 +CCn1nc(C(=O)Nc2nc3cc(C)c(C)cc3s2)cc1C +CN(C)C(=O)c1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1 +CCCN(CC1CC1)C(=O)Nc1ccc(C(=O)NCC)cc1C +COc1cccc(CSc2nnc(C3CC3)n2C2CC2)c1 +O=C(Cc1c(F)cccc1F)Oc1cccc(C(=O)NC2CC2)c1 +CN(C)C(=O)c1cc2c(s1)CCN2C(=O)c1ccccc1 +O=C(NC1c2ccccc2CC1O)C1(c2ccccc2)CC1 +Cc1nc(NC(=O)C(C)C)sc1-c1nc(-c2cccs2)no1 +CC(C)n1cc2c(c1-c1ccc(Cl)cc1)c(=O)n(C)c(=O)n2C +COc1ccc(CCC#N)cc1OCc1ccccc1 +CCOC(=O)CN(CC)C(=O)c1c[nH]c2ccccc12 +COc1ccc(OCC2CN(C(=O)c3ccc(F)cc3)CCO2)cc1 +CC(=O)c1ccccc1NCC(=O)Nc1ccc(C#N)cc1 +COc1ccc(F)c(NC(=O)C2(c3cccc(F)c3)CCOCC2)c1 +CCC(C)C(C)NC(=O)N1CCC(CC(N)=O)CC1 +Cc1ccc(CC(C)NC(=O)c2cnn(-c3ccncc3)c2C)c(C)c1 +OCC(O)CSc1ccnc(C2CCCC2)n1 +Cc1cccc2c(=O)n(CCC(=O)NCC(O)c3ccco3)cnc12 +CS(=O)(=O)N1CCN(C(=O)CCc2ccc(C#N)cc2)CC1 +Cn1ccnc1SCC(=O)Nc1ccccc1C(N)=O +COCC1CCN(C(=O)CCc2ccco2)CC1 +Cc1cc(Cl)ccc1NC(=O)CN1CCCCCC1=O +COc1ccc(CC(=O)N(Cc2cnc3ccccn23)C2CC2)cc1 +Cc1cc(C)nc(NC(C)c2nnc3n2CCC3)n1 +CNC(=O)C1CCCN1c1nnc(C)c(C)c1C#N +Cc1cc(C)n(C(=O)c2cc(F)c(F)cc2Cl)n1 +CCC(C)N(C)C(=O)c1c(F)cc(Br)cc1F +CCN(Cc1cccc(F)c1)C(=O)c1cc(C)on1 +Cc1noc(C)c1Cn1cnc2c1c(=O)n(C)c(=O)n2C +COCCOCCNC(=O)c1cc(C)ccc1C +Cc1ccnn1CCNC(=O)c1noc2c1CCCC2 +CCCc1noc(Cn2cc(C(=O)NC)ccc2=O)n1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)Nc1ccnn1CC(C)C +Cc1onc(-c2ccccc2Cl)c1C(=O)n1cccn1 +COc1ccc(-c2cnc(CN3CCOCC3(C)C)o2)cc1 +Cc1cccc(COc2cccc(CNn3cnnc3)c2)c1 +Cc1ccc2[nH]c(C(=O)Nc3ccc(C#N)cc3)cc2c1 +COCC(=O)N1CCc2ncnc(-c3cnn(C)c3)c2CC1 +O=C(Nc1ccc2c(c1)OC1(CCCC1)O2)c1ccncc1 +Cc1ccc(C(=O)N2CCN(c3ncccc3C#N)CC2)c(O)c1C +N#Cc1c(COC(=O)c2ccc3c(c2)NC(=O)CO3)cn2ccccc12 +Cc1ccc(F)cc1S(=O)(=O)N1CCC(CC(N)=O)CC1 +COc1ccc2nc3oc(C(=O)NCc4cccs4)cc3cc2c1 +CN1CCN(C(=O)c2nccc3c(F)ccc(N)c23)CC1 +CC1CC1c1ccc(CN(C(=O)C2CC(=O)N(C)C2)C2CC2)o1 +CC(C)N1CC(C(=O)NCCNc2cccc(F)c2C#N)CC1=O +Cn1c(N)c(C(=O)COC(=O)c2ccccc2O)c(=O)n(C)c1=O +O=C(c1ccc(-c2noc(-c3ccccc3)n2)s1)N1CCOCC1 +CCC(=O)Nc1nnc(C2CC(=O)N(c3ccc(F)cc3)C2)s1 +CC(C)CCC(C)NC(=O)c1ccc(N)cc1Cl +COc1cc(CNC(=O)CNC(=O)C2CCCC2)ccn1 +CC(=O)Nc1cccc(NC(=O)c2ccc(C)s2)c1C +O=c1cc(N2CCOCC2)nc2scc(-c3ccc(Cl)cc3)n12 +COC(=O)c1ccc(C(=O)Nc2c(C)cccc2C)nc1 +CN(CC(=O)Nc1c(Cl)cccc1Cl)C(=O)c1cnccn1 +COC(=O)c1occc1C1Nc2ccccc2C(=O)N1C +O=C(NC1CCN(c2cccc(Cl)c2)C1)c1ccncc1Cl +O=C(COC(=O)c1csc2ccccc12)NCc1ccco1 +COc1ccc(C(=O)Nc2ccc3c(c2)C(=O)NCC3)cc1 +CCCc1nnc(N2CCC3(CCCN(CC4CCC4)C3=O)C2)s1 +Cc1nc2ccc(NC(=O)c3c(C)noc3C(C)C)cc2s1 +CCOc1ccccc1NC(=O)Cc1c(C)nn(C)c1C +Nc1cccnc1SCC(=O)NCc1ccco1 +CNC(=O)c1ccccc1C#CCNC(=O)NC1CCCCC1 +CCCCCC(=O)N(C)Cc1ccc2c(c1)OCO2 +CC(C)c1nc(CN(C)C(=O)c2cnn3ccccc23)no1 +N#CCCN1C(=O)CNc2cc(Br)ccc21 +N#CC(C(=O)c1ccc(C(F)(F)F)nc1)c1nc2ccccc2[nH]1 +NC(=O)N1CCCC(C(=O)Nc2ccc(F)cc2OCC2CC2)C1 +CC(O)CN1CCN(CCNS(=O)(=O)c2ccccc2)CC1C +COC(=O)c1sccc1NC(=O)CCC1CCCO1 +CC(C)(C)NC(=O)CN1C(=O)c2ccccc2S1(=O)=O +c1cncc(-c2nc(NCCc3c[nH]cn3)ncc2-c2ccsc2)c1 +Cc1cccc(CC(=O)OCC(=O)NC(C)(C)C)c1 +COc1ccc(S(=O)(=O)N2CCN(C(C)=O)CC2)cc1Cl +COc1ccc(C2CN(c3nccs3)CC2NC(C)=O)cc1 +C=CCNc1ccc(S(=O)(=O)N(CC)CC)cc1 +CC(NC(=O)Nc1ccccc1CC(N)=O)c1ccc2ccccc2c1 +Cc1ccc(NC(=O)c2csc(-c3cnccn3)n2)cc1Cl +Cc1cc(-c2cncnc2C2CCCN(C(=O)c3cccnc3)C2)on1 +CC(c1cccnc1)N1CCN(Cc2cnc3cnccn23)CC1 +O=C(COC(=O)c1ccc(F)cc1)Nc1ccc2c(c1)CCC2 +CCCCN(CCOC)C(=O)c1ccc2[nH]ccc2c1 +Cc1cc(C)nc(Nc2nc(C(=O)Nc3nnc(C)s3)cs2)n1 +CCC(C)NC(=O)CN1CCN(C(=O)c2cccc(C)c2O)CC1 +O=C(CC1Cn2cccc2C1=O)Nc1ccc(Br)cc1 +O=C(OCC1CC=CCC1)C1CCCN1C(=O)Cc1cccs1 +CC(C)C(NC(=O)c1ccccc1)C(=O)Nc1ccccc1C(N)=O +CCn1nc(C)cc1C(=O)N1CCOC2CCC1C2OCC1CC1 +CC1CC1C(=O)Nc1cccc(C(=O)NCCOc2ccccc2)c1 +N#Cc1ccc(OC(=O)Cc2coc3ccc(F)cc23)cc1 +c1ccc2c(c1)OCC(c1nc(-c3ccc(-n4ccnc4)nc3)no1)O2 +Cc1ccc(NC(=O)c2nc3ccccc3n(C)c2=O)cc1 +Cc1cc(OCc2noc(-c3ccccn3)n2)ccc1Cl +COc1cccc(Oc2ccc(NC(=O)C3CC(=O)N(C)C3)cc2)c1 +CCn1cc(-c2cc(C(F)F)c3c(C)nn(CC)c3n2)cn1 +CC(C)Oc1ccc(C#N)cc1NC(=O)c1cc(-c2ccncc2)on1 +Cc1cc(C)c(C(=O)NCCN(C)C(=O)OC(C)(C)C)c(C)c1 +CCOC(=O)c1ccn(-c2ccccc2NCc2c(C)noc2C)n1 +Cc1cccc(C(=O)NCCOc2ccccc2N)c1 +COC(=O)CN(Cc1ccc(F)c(F)c1)Cc1cc[nH]n1 +COCCOc1ccc(C#N)cc1NC(=O)C1CC1 +NC(=O)C1CCN(c2nc(-c3ccccc3)nc3ccccc23)CC1 +CC(NC(=O)CC1OC(=O)c2ccccc21)c1ccc(F)c(F)c1 +CC(C)(C)C(=O)NCCCC(=O)Nc1cc(F)ccc1F +CCn1ncc2c(C(=O)N(C)C)cc(-c3cccs3)nc21 +CCCCNC(=O)c1ccc(CNC(=O)c2occc2C)cc1 +Cc1cc(C)cc(C(=O)NCC(=O)NCCCn2cccn2)c1 +Cn1c(=O)c2nc3c(nc2n(C)c1=O)[nH]c1ccccc13 +Cc1cc(NC(=O)C2CCOC2)c2ncccc2c1 +Cc1ccc(Cn2cnc(NC(=O)c3c(Cl)c(C)nn3C)n2)cc1 +CCn1nccc1C(=O)Nc1cc(C(=O)OC)ccc1C(=O)OC +Cc1nn(C)cc1-c1nn2c(Cc3ccccc3Cl)nnc2s1 +CCc1nnc(C2CCN(C(=O)C(CC)c3ccccc3)CC2)s1 +CCc1onc(C)c1NC(=O)NCC1(Cc2ccccc2)CC1 +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)c1ccc2cc[nH]c2c1 +Cc1ccc(NC(=O)CN(C)S(C)(=O)=O)nc1 +CCOC(=O)c1oc2ccccc2c1CSc1n[nH]c(N)n1 +O=C1CC(CO)CN1CCOc1c(Cl)cccc1Cl +Nc1c(-n2cc(Br)cn2)ccc2ncccc12 +CCc1nn(C)c(NC(=O)N(C)Cc2ccc3nonc3c2)c1C +Cc1cccc(OS(=O)(=O)c2ccc(F)cc2)c1 +Cc1ccc(OC(C)c2ccnc3ncnn23)cc1 +Cc1nnc(Cn2cnc3sc(C)cc3c2=O)o1 +N#CCC(=O)CCOc1ccc(Oc2ccccc2)cc1 +O=C(c1ncn(-c2ccccc2)n1)N1CCc2cc(F)ccc2C1 +Cc1cc(C)n(-c2ccc(=O)n(CC(=O)NCC(C)C)n2)n1 +Cc1ccc(OC(C)C(=O)N2CCC(C(N)=O)C2)cc1 +COCCNC(=O)CNC(=O)c1cc(C)cc(Br)c1O +COC(=O)c1sc(NC(=O)COC2CCCCC2)nc1C1CC1 +COc1ccc(CNC(=O)CCn2ccc3ccccc32)cc1OC +O=C(Nc1nccs1)C1CCCN(Cc2cnc3ccccn23)C1 +CC(C#N)NC(=O)CC(c1ccccc1)c1ccccc1 +Cc1cc(C(=O)NCC(=O)NCc2nc3ccccc3[nH]2)nn1C +CCNC(=O)C(C)NC(=O)CCc1ccsc1 +CC(C(=O)NC1CC1)N1CCN(C(=O)CCc2cccc(F)c2)CC1 +Fc1cccc(Cl)c1-c1nn2c(-c3cnccn3)nnc2s1 +CN(CC(=O)NC1CCc2c(F)cccc21)c1ccc(C#N)cn1 +O=C(CCc1ccco1)Nc1cccc(N2CCCC2=O)c1 +CN(Cc1ccccc1F)C(=O)CNC(=O)c1cc2occc2n1C +O=C(NCC#Cc1ccc(F)cc1)NCc1cccs1 +COc1ccc(C(=O)OCc2ccc(-n3cccn3)cc2)cc1 +CCNC(=O)CNC(=O)NC(C)c1cccc(OC(F)F)c1 +CN1CCC(NC(=O)NCc2cc(F)cc(Br)c2)C1=O +CC(C)(C)c1ccc(O)c(NC(=O)CCNC(=O)C2CCC2)c1 +CCCCS(=O)(=O)NCC(=O)NC1CCCC(C)C1 +NC(=O)c1snc(S(=O)(=O)C2CCCCC2)c1N +COc1ccc(NC(=O)N(C)Cc2cccc(C#N)c2)cc1 +CC(=O)c1ccccc1NC(=O)CNc1ccc(F)cc1C +OCc1c(-c2ccc3ccccc3c2)nc2n1CCS2 +CC(C)C(NC(=O)NC(C)(CO)C1CCCCC1)c1nccn1C +CC(C)c1cc(C(=O)NCC2OCCc3ccccc32)on1 +CC(=O)c1ccc(-n2nnnc2-c2ccc(C)c(N)c2)cc1 +CC(=O)c1cc(C(=O)N2CCC(Oc3ccccc3)CC2)n(C)c1 +CC(CC(=O)NCCN1CCOCC1)c1ccccc1 +COCCNC(=O)c1cc(S(=O)(=O)N2CCCC2)cs1 +O=C(NCCc1nncn1C1CC1)c1ccc(Cl)c2cccnc12 +Cn1ccc(C(=O)NC2CCc3ccccc32)cc1=O +Cn1c(=O)c2c(ncn2CC(=O)Nc2ccccc2)n(C)c1=O +COc1cc(CNc2cnn(-c3ccccc3)c2)cc(Cl)c1OC +O=C(CCN1CCOCC1)c1cc2ccccc2o1 +Cc1ccccc1CC(=O)NCc1nnc2ccccn12 +O=C(NC(C(=O)Nc1cc[nH]n1)c1ccccc1)C1CCC1 +CCOC(C)c1ccc(-c2ccc(N(C)C)nn2)cc1 +O=C(Nc1c[nH]ccc1=O)C1(c2ccccc2)CC1 +CC1CN(C(=O)CSc2ncc(-c3ccc(F)cc3)[nH]2)CC(C)O1 +Cc1c(CNC(=O)C2CCCN2C(=O)c2ccccc2O)cnn1C +CCN(CC)S(=O)(=O)c1cccc(NC(=O)c2cnccn2)c1 +C=CCNC(=O)C(C)n1cnc2c1c(=O)n(C)c(=O)n2C +CCCCNC(=O)NC(C)c1ccc(OC)cc1 +COC(C)(C)c1noc(Cn2cnc3c(oc4ccccc43)c2=O)n1 +COc1ccc(NC(=O)c2cccc(N)c2)cc1OC +CC1CN(C(=O)c2csc(-c3ccc4c(c3)OCO4)n2)CC(C)O1 +Cc1nc(CN2CCOC(CCc3ccccc3)C2)no1 +Cn1c(SCC(=O)Nc2sccc2C(N)=O)nc2ccccc21 +Cc1cccc(NC(=O)CCn2c(=O)oc3ccc(Cl)cc32)c1 +c1ccc(-n2nc(-c3cccnc3)c3c2CCNC3)cc1 +CCc1ccc(C(=O)N2CCOCC2c2ncon2)cc1 +CCCCc1nnc(NC(=O)c2ccc3c(c2)OCO3)s1 +Cc1cc(C(=O)N(C)Cc2ncnn2C)c2ccccc2n1 +CC1CC1C(=O)Nc1cccc(C(=O)Nc2cccc3cn[nH]c23)c1 +O=C(C1CC2C=CC1C2)N1CCN(c2ccc(F)cc2)CC1 +Cc1cc(C)c(-c2nc(-c3ccc(C#N)cn3)no2)o1 +CCCc1cc(=O)[nH]c(SCC(=O)N2CCCC(C)C2)n1 +COc1ccc(OC)c(S(=O)(=O)N(C)CCc2ccccn2)c1 +O=C(CCOc1cccc(Br)c1)N1CCCCC1 +O=C1CCC2(CCCN(C(=O)OCc3ccccc3)CC2)N1 +Cc1ccc(Cc2nc(C(=O)OCCn3cccn3)cs2)cc1 +CCOc1ccccc1CNC(=O)Nc1cc(OC)ccc1F +C=CCNC(=O)c1ccc(-c2cccc(-n3cccn3)c2)o1 +Cc1ccc(-c2cc(CNC(=O)c3ccc[nH]c3=O)no2)cc1 +CCCNC(=O)CC(NC(C)=O)c1ccc(OC)cc1 +CC(CNC(=O)NC(C)c1ccncc1)Nc1ccccc1 +CC(C)(CNC(=O)c1ccccc1)CNC(=O)c1ccccc1 +CNC(=O)NC1(c2ccc(Br)cc2)CCC1 +CCOc1ccc(C(=O)Nc2ncc(C)s2)nn1 +Cc1ccc(C2CC(=O)CC(=O)N2C(C)(C)C)cc1 +CCC(C(=O)NCCNS(C)(=O)=O)c1ccccc1 +CN(Cc1ccc(C#N)cc1)C(=O)c1cccnc1OCC(F)F +COC(=O)c1ncn(Cc2cc(Br)ccc2F)n1 +Cc1ccc(Cc2nc(C(=O)N3C(C)COCC3C)cs2)cc1 +O=C(c1ccc(F)cc1)N1CCOC(c2ccccn2)C1 +CC(CNC(=O)NCC(=O)N1CCCCC1)Nc1ccccc1 +Cc1ccccc1-c1noc(CNC(=O)C(C)(C)C)n1 +CCOC1CCCN(C(=O)c2ccc(=O)n(-c3ccc(F)cc3)n2)C1 +CC(=O)Nc1cccc(C(C)OC(=O)Cc2ccc(F)cc2F)c1 +CCN(CC)C(=O)CCC(=O)Oc1ccc(Cl)c(C)c1 +CSc1ccccc1NC(=O)c1scnc1C +CCOc1ccc(C2(CNC(=O)C(C)C)CCOCC2)cc1 +CC(=O)c1cc(CC(=O)NCCCN2CCc3ccccc32)cs1 +Cc1noc(C)c1CC(=O)Nc1nc(-c2ccc(F)cc2)c(C)s1 +COc1ccc(Br)c(C(=O)NC2CC2)c1F +CC(=O)N1CCC(C(=O)NC(C)c2cccc(OC(F)F)c2)CC1 +COc1cccc(CN(C)Cc2nc(C)cs2)c1OC(C)C +Cc1cnc(C(=O)NCCNC(=O)c2ccc(C)c(F)c2)cn1 +O=C(Nc1ccccc1Cl)c1cc(=O)[nH]c2ccccc12 +CCC(Sc1ccc(NC(C)=O)nn1)C(=O)OC +Cc1cc(C)cc(NC(=O)N2CCCC2c2cc(C)on2)c1 +CCCn1cc(NC(=O)NCCC2CCCCO2)cn1 +Nc1ccccc1NC(=O)Cc1ccccc1Cl +Cc1nc(-c2ccc(Cl)cc2)sc1C(=O)NCCCC(N)=O +COC(=O)Cc1csc(NC(=O)CCC2CCCCC2)n1 +O=C(NCc1nccn1Cc1ccccc1)NCC1CCC1 +O=C(Nc1ccc(-n2cnnn2)cc1)C1(c2cccs2)CCCC1 +CCOC(=O)Cn1nc(C)c(NC(=O)c2cnccn2)c1C +Cc1cc(F)cc(S(=O)(=O)N(CCO)Cc2cccnc2)c1 +O=C(NCC#CCOc1ccc2cccnc2c1)NCc1ccccc1 +O=S1(=O)N(Cc2ccccc2)CCN1Cc1ccccc1 +CCNC(=O)c1ccc(NC(=O)CCNC(=O)C(C)(C)C)c(C)c1 +CCCc1nnc2sc(-c3cccc(N)c3C)nn12 +CC(=O)C(C)Oc1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +N#Cc1nc(N2CCOC(C(N)=O)C2)ccc1Cl +CC1CN(C(=O)CCc2ccncc2)CCC1(C)O +CCC1(CC)Oc2ccc(Cl)cc2N(CCC#N)C1=O +COc1ccc(CN(C)C(=O)CCC#N)c(OC)c1 +Cc1ccc2c(c1)S(=O)(=O)N=C(NCc1ccccc1)N2 +CC(C)(O)CN1CCN(C(=O)Cc2c(F)cccc2Cl)CC1 +CN(Cc1ccccc1N1CCCC1)C(=O)CCNC(=O)C(C)(C)C +CCOC(=O)N1CCN(C(=O)c2cccc(OC)c2OC)CC1 +Cc1ccc2nc(C)c(NC(=O)CCCc3ccccc3)c(=O)n2c1 +CC1(c2[nH]ncc2C(N)=O)CCN(c2cnccn2)CC1 +Cc1cc(C(=O)Nc2ccccc2C(N)=O)ccc1F +CCc1c(C(=O)NC(C)c2ccncc2)cnn1-c1ccccc1 +CCC(=O)Nc1nnc(SCC(=O)N(CC)CC)s1 +COC(=O)c1ccc(NCC(=O)N2CCc3sccc3C2)cc1 +CC(C)(C)OC(=O)N1CCc2c(CO)n[nH]c2C1 +Cc1csc(NC(=O)c2ccccc2SC(C)C)n1 +COCC(C)NC(=O)CSc1nnc(-c2ccc(F)cc2)o1 +NC(=O)CCN(C(=O)C1CC1c1ccc(F)cc1)c1ccccc1 +CCOC(=O)N1CCN(C(=O)NC(C)c2ccccc2Cl)CC1 +CCOc1ccc(S(=O)(=O)Nc2ccccc2C)cc1NC(C)=O +Cn1cc(C(=O)Nc2cccc(OCc3cccc(F)c3)c2)cn1 +CNC(C(N)=O)c1cc(OC)c(OC)cc1Br +COc1ccc(C(C)N(C)C(=O)NCCc2nc(C(C)C)no2)cc1 +Cc1ccnc(NC(=O)CCc2nnc(-c3ccccc3)o2)c1 +CS(=O)(=O)Nc1cccc(CNC(=O)c2cn3ccccc3n2)c1 +CCc1nc2ccccn2c1N(C(C)=O)c1ccc2c(c1)OCO2 +Cc1ccc(OCCN2C(=O)C(C)(C)Oc3cc(N)ccc32)cc1 +COc1cccc(CNC(=O)C(C)Oc2cccc(C)c2)c1 +CCN(CC)C(=O)CCC(=O)NC1CCc2cc(Cl)ccc21 +CC(C)n1cc(N)cc1C(=O)NCc1ccncc1 +COc1cccc(CCNS(=O)(=O)c2cccc(O)c2)c1 +CCc1cc(C(=O)N2CCC(O)(CC)C(O)C2)ccn1 +CCCn1ncc(CN2CCOC(CCc3ccccc3)C2)c1C +Cc1cnn(CCCNc2ccc(C(=O)Nc3ccccc3)nn2)c1 +COCCC(=O)N1CC(c2ccccc2)OCC1(C)C +CC(C)CCNc1ncnc(N(C)Cc2ccccc2)c1N +CCOc1ccccc1NC(=O)COC(=O)c1ccccc1N +CC(C)NC(=O)CN(C)C(=O)Nc1ccc(F)cc1F +CC(C)C(=O)Nc1cccc(NC(=O)Nc2ccccc2)c1 +CC(C)CN(C)C(=O)CCc1c[nH]c2ccccc12 +CC(C)N(CCCO)C(=O)c1cccc(Cl)c1 +C#CC(CC)(CC)NC(=O)COc1ccc(NC(C)=O)cc1 +CCOc1cc(Cl)c(C(N)C(F)(F)F)cc1OCC +Cc1ccccc1OCCCNC(=O)c1scnc1C1CC1 +Cc1ccc(S(=O)(=O)CCC(=O)NCc2ccc(F)cc2)cc1 +CC1CCCN(C(=O)COC(=O)Cc2n[nH]c(=O)c3ccccc23)C1 +Cc1ccnc(N2CCCC2CC(=O)c2cnn(C)c2)n1 +N#Cc1ccc(Cl)c(NC(=O)c2cn(Cc3ccccc3)nn2)c1 +Nc1nc(SCC(=O)Nc2ncc(Cl)cc2Cl)n[nH]1 +CC(C)CC(=O)NCC(=O)Nc1ccc(F)cc1 +COc1cccc(OCCNC(=O)NCC2CC2C)c1 +COC(=O)c1ccnc(Oc2cccc(C(C)=O)c2)c1 +CC(C)C(NC(=O)CSc1ncn[nH]1)c1ccc(F)cc1 +CN1CCN(S(=O)(=O)c2ccc3c(c2)CCO3)CC1 +O=C(Nc1ccc2c(c1)COC2)NC1CCN(c2ccccc2)C1=O +CCN(CC)C(=O)CCC(=O)NC1(c2noc(C)n2)CCCC1 +CC(NC(=O)c1c[nH]nc1-c1ccccc1F)c1ccncc1 +CCn1cnnc1SCC(=O)Nc1cccc(C)c1 +c1ccc(-c2nnc(-c3ccc4c(c3)OCCO4)o2)cc1 +O=C(c1ccccc1O)N1CCN(Cc2cccc3[nH]ccc23)CC1 +N#CCOc1cccc(CC(=O)NCC(=O)Nc2cccc(F)c2)c1 +CCCC(C)(CO)NC(=O)NCc1ccc(-n2ccnc2C)c(F)c1 +Cc1ccc(CNC(=O)CN2CCOc3ccccc32)cc1 +COc1ccc(Cc2nc3ccc(N)cn3c2CC#N)cc1OC +CN(Cc1nc(-c2cccs2)no1)C(=O)c1cccs1 +COc1ccc(CNC(=O)c2cc(Br)ccc2F)cc1 +CCCCCN(C)C(=O)c1n[nH]c2ccc(N)cc12 +CC(CNC(=O)Cn1cncn1)Oc1cccc(Br)c1 +CCOC(=O)CC(O)(c1nc(C)cs1)C(F)(F)F +CCc1ccccc1NC(=O)CN1CCN(c2ncccc2C#N)CC1 +COc1ccccc1CNC(=O)Cn1c(=O)c(C(N)=O)cn(C)c1=O +O=C(NCC1CC1)c1cn[nH]c1-c1cccc(Br)c1 +CCCn1nnnc1CN1CCC(C(=O)NCc2ccccc2)CC1 +CN1C(=O)C(Cc2ccc(F)cc2)Oc2ccc(O)cc21 +CCNC(=O)N1CCN(C(=O)Cc2c[nH]c3cc(Cl)ccc23)CC1 +C=CCNC(=O)COc1ccc2c(CC)cc(=O)oc2c1 +COc1cc(S(=O)(=O)NCCC(C)C)ccc1NC(C)=O +Cc1nc(C)c(CCC(=O)NC(C)(C)CC(C)(C)C)c(=O)[nH]1 +CNc1snc(C)c1C(=O)N1CCOC(c2ccc(F)c(C)c2)C1 +O=S(=O)(C1=Cc2ccccc2CC1)N1CCC2(CC1)OCCO2 +Cc1cnc(C(=O)Nc2ccc(-c3ccccc3)cc2)cn1 +CC1CCCN(C(=O)NCc2cc(Cl)c3c(c2)OCCO3)C1 +O=C(NCC(F)(F)F)c1cccnc1N1CCCCC1 +Cc1ccc(C(O)(CC(=O)NCc2ncc(C)s2)C(F)(F)F)o1 +CCC(=O)c1ccc(OCC(=O)Nc2nccn(C)c2=O)cc1 +COCc1c(C(=O)NC2CCC(n3cnnc3)CC2)noc1C +COC(=O)CN1CCc2c(N)cc(Cl)cc2C1 +Cc1nc(C2CCN(C(=O)C3CC=CC3)CC2)no1 +Cc1cc(C)nc(Sc2nnc(C)c3ccccc23)n1 +CCn1ccc(NC(=O)C2(c3ccccc3)CCOCC2)n1 +CCCC1CN(C(=O)C2CCN(C(=O)OC(C)(C)C)C2)CCO1 +Clc1cccc(OCCNCc2cnc(N3CCOCC3)nc2)c1 +CCOC(=O)N1CCN(C(=O)c2sccc2Br)CC1 +CC(=O)N1CCC(C(=O)NC(C)c2ccc(SC(C)C)cc2)CC1 +O=C1CCC(C(=O)NCc2ccc(CN3CCc4ccccc43)cc2)N1 +Cc1csc(C(C)NC(=O)C(C)Sc2ccccn2)n1 +CNC(=O)c1cccc(CNC(=O)CC(F)(F)F)c1 +COC(=O)C(NC(=O)c1cc(C)no1)C(C)(C)C +CC(=O)N(C)CC(=O)OCCCc1cccc(C)n1 +Nc1cnc2scc(-c3ccc4c(c3)OCCO4)n12 +C=CCn1c(SCc2ccccn2)nnc1-c1cccnc1 +Cc1noc(C2CCN(C(=O)NC(C)c3ccccc3)CC2)n1 +Nc1ccc(C(=O)Nc2ccc(CCO)cc2)nn1 +CCOC(=O)c1c(C)csc1NC(=O)c1ccncc1 +O=C(c1cccc(Cl)c1Cl)N(CCO)C1CCCC1 +CC(C)C(=O)Nc1ccc(CC(=O)N(C)c2ccccc2)cc1 +COCc1ccc(C(=O)Nc2c(C)cc(C)cc2C)o1 +CC(C)OCCCNC(=O)C1CCN(C(=O)C(C)(C)C)CC1 +Cn1nccc1CNC(=O)NCC(C)(C)c1cccc(Cl)c1 +COC(=O)c1sc(NC(=O)C2CCCCC2)nc1C1CC1 +CN(C)c1ncccc1C(=O)N1CCC(N2CCNC2=O)CC1 +CC(=O)c1ccc(Cl)c(NC(=O)CCCc2ccccn2)c1 +COc1ccc(N2C(=O)c3ccccc3NC2c2ccccn2)cc1 +CC(Cc1ccsc1)Nc1ncnc2[nH]cnc12 +COc1nccnc1N1CCC(NC(=O)c2nccc3ccccc23)C1 +CC(NS(=O)(=O)c1ccc(C#N)cc1)c1ccccc1 +Cn1nc(C(=O)Nc2cccc(Cl)c2)c(=O)c2ccccc21 +OCc1c(Cl)cccc1N1CCc2sccc2C1 +CCCCN(C)C(=O)C1CN(S(=O)(=O)C2CC2)C1 +Cc1ccc(CNC(=O)C2CC(=O)N(Cc3ccccn3)C2)o1 +CC1CC(C)CN(C(=O)c2ccc(NC(=O)C(C)C)cc2)C1 +CCC(NC(=O)c1cc(=O)c2ccccc2o1)c1ccc(C)cc1 +CCC(=O)Nc1ccc(S(=O)(=O)NC(C)=O)cc1 +CN(CCOCC1CC1)C(=O)c1ccc(-n2cnnn2)cc1Cl +CC(=O)N1CCc2c(c(-c3cccc(N)c3)nn2CCC(N)=O)C1 +COCCC1(CNC(=O)Nc2cc(-c3ncco3)ccc2C)CCC1 +Cc1nc(CN2C(=O)CCC3C2CCN3C(N)=O)cs1 +CCOc1ccc(S(=O)(=O)Nc2ccc(CCO)cc2)cc1 +O=C(CSc1ncn[nH]1)NCCc1ccc(Cl)cc1 +Cc1c(C(=O)OCCNC(=O)c2ccncc2)sc2ccccc12 +COc1cccc(-c2nc3c(s2)C(=O)CCC3)c1 +CC(C)(C)n1nc(C(=O)C(C#N)c2ccccn2)cc1C1CC1 +CCc1ccc(CN2CCN(C(=O)c3ccccc3F)CC2)cc1 +CNC(=O)C1CC=CCC1C(=O)Nc1ccc(C(=O)OC)cc1 +Cc1nnsc1CN(C)C(=O)c1nnn(Cc2ccccc2)c1C +Fc1ccc(F)c(NCc2nnc(-c3ccccc3)o2)c1 +O=C(NCc1cccnc1)c1ncoc1-c1cccs1 +CCCCN(C)S(=O)(=O)N1CCCCC1CO +Cc1ccc(S(=O)(=O)NCc2ccc(C)s2)cc1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc(OC)nc1 +CCC(CO)NC(=O)c1c[nH]c2ccccc2c1=O +Cc1ccccc1Nc1nc(N2CCOCC2)nc2c1cnn2C +COCCNC(=O)CNc1cc(F)c(F)c(F)c1 +Cn1nnnc1SCc1nc2c(oc3ccccc32)c(=O)[nH]1 +CCc1nnc(CNC(=O)c2cc(C(C)C)nn2C)s1 +CCOc1ccc(CN2C(=O)C(NC(C)=O)c3ccccc32)cc1 +CC1CCCCC1NC(=O)CNc1ccc(-n2cccn2)cc1 +COc1ccccc1C1NC(=O)c2[nH]nc(-c3ccc(C)cc3)c21 +Cc1nc2cc(-c3nnc(CCO)o3)ccc2n1C(C)C +CCS(=O)(=O)c1nnn(CCOc2cccc(C)c2)c1N +CN1C(=O)c2ccc(Cl)cc2NC1C1CCOC1 +O=C(Cn1cnc2ccccc2c1=O)NCCOc1ccccc1F +Cc1nc(CC(=O)N2CCc3c(nc(CC4CC4)[nH]c3=O)C2)cs1 +Nc1cc(C2CCN(C(=O)c3cccs3)CC2)no1 +CC(C)NC(=O)CNC(=O)C1CC(=O)N(c2ccccc2)C1 +Nc1oc(-c2cccnc2)cc1C(=O)c1ccc(F)cc1 +Cc1ccc(S(=O)(=O)N2CCOCC2(C)C)c(Br)c1 +Cn1ncc2c(Nc3ccc(CC(N)=O)cc3)ncnc21 +Cc1ccc(C(=O)Nc2cccc(OCC(=O)N(C)C)c2)cc1C +COc1cccc(OCC(CC#N)N2CCCCC2)c1OC +O=C(CCn1sc2ccccc2c1=O)Nc1nnc(C2CC2)s1 +CCC(C)C(=O)NCC(=O)NCC(=O)NC1CC1 +CC1=Nc2ccccc2NC(N)=C1c1cccs1 +Cc1nn(C)c(C)c1C(=O)NCCc1cccc(F)c1 +NC(=O)c1c(NC(=O)NCCO)sc2c1CCCC2 +COc1ccc(C(C)(C)NC(=O)Cn2nc(C)cc2N)cc1OC +COCCn1ccc2cc(NC(=O)NCc3cccnc3)ccc21 +CC(C)(CNS(=O)(=O)c1cccc(F)c1C#N)c1ccncc1 +CN(CC(F)(F)F)C(=O)C1CCN(CC(F)(F)F)CC1 +COC(=O)c1ccc(N2CCN(c3ccc(F)cn3)CC2)cc1 +Cc1cc(C)n2nc(SC(C)c3nc(C4CC4)no3)nc2n1 +CN(CCc1noc(-c2cc3ccccc3[nH]2)n1)C(=O)c1ccccc1 +COC(=O)c1ccc(NC(=O)CNCc2ccccc2Cl)cc1 +O=C(CC1CCCC1)NC1CCSc2ccc(Cl)cc21 +COc1ccc(C(=O)NCCNC(=O)C2(O)CCCC2)cc1 +CCc1ccc(CNCC(=O)NCc2ccco2)cc1 +CC(C)c1nccn1Cc1cccc(NC(=O)CC2CCCO2)c1 +CNC(=O)c1cccc(OC(=O)CC(C)c2ccccc2)c1 +O=C(NC1C=CCCC1)C(O)C(O)c1nc2ccccc2s1 +Nc1nc2c(N3CCN(c4cccc(Cl)c4)CC3)cccn2n1 +Cc1cscc1C(=O)NCC(O)c1cc2ccccc2s1 +CCN1C(=O)C(O)(c2c(C)[nH]c3ccccc23)c2cc(Cl)ccc21 +CC(CC#N)N1CCN(CCOc2ccc(Cl)cc2)CC1 +O=C(CCC1N=C(O)N(Cc2ccccc2)C1=O)N1CCCCCC1 +Cc1c(NC(=O)c2noc3c2CC(C(C)(C)C)CC3)cnn1C +CC(C)c1nnsc1CNC(=O)c1cccc(Cn2cccn2)c1 +CC(=O)Nc1cc(NCc2cccc(F)c2)ccc1C +O=C(Nc1ccccc1OC(F)F)c1ccc2ccccc2n1 +O=C(Cn1ncc2c(N3CCOCC3)ncnc21)NCc1ccco1 +CC(C)CC(C)N(C)c1ccc(S(N)(=O)=O)cc1N +CN(Cc1cnc(N)nc1)C(=O)CCCc1ccc(Cl)cc1 +Cc1cc(OCC(=O)NC(C)C(N)=O)ccc1C(C)C +Cc1ccc(C(=O)Nc2ccc(NC(=O)OC(C)(C)C)cc2)cn1 +CCCNC(=O)Nc1ccc(OCC(F)(F)F)nc1 +Cc1ccnc(NC(=O)c2ccc(Cl)cc2O)c1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)N(C)CCc1ccccc1 +CCc1ccccc1NC(=O)NCc1ccc(OC)c(OC)c1 +O=C(Nc1nccs1)c1coc(-c2ccccc2)c1 +O=C(CNC(=O)c1cccc(Cl)c1)NC1CCCC1 +CCN(CC(=O)OC)C(=O)C(NC(C)=O)C(C)C +CCC(CO)NC(=O)Nc1ccc(OCC(F)(F)F)c(C)c1 +CC(=O)N(C)c1ccc(NC(=O)NC(C)(C)c2nc(C)cs2)cc1 +CC(=O)N1CCC2(CC1)N=C(c1ccccc1)C(c1ccccc1)=N2 +Cc1cccc(-c2ccc(C(=O)NCc3ccc(C)n3C)c(=O)[nH]2)c1 +O=C(c1ccnnc1)N1CCOC2CC(COCC3CC3)CC21 +Cc1ccccc1N1CCN(C(=O)Cc2cccc(O)c2)CC1=O +COc1cccc2c1CCNC2C1CC(=O)N(C(C)C)C1 +Fc1ccccc1-c1nnn(Cc2ccccn2)n1 +CC(=O)Nc1ccc(OCC(O)CSc2ccc(C)cn2)cc1 +Cc1cccc(C(C)CNC(=O)c2ccccn2)c1 +COCCOc1ccc(NC(=O)c2cn[nH]n2)c(C)c1 +CNC(=O)CNS(=O)(=O)c1ccc(Br)cc1 +CCN(CCNC(=O)N(C)CC1CCCO1)c1cccc(C)c1 +Cc1nn(CCC#N)c(C)c1CCC(=O)N(C)CC(=O)N(C)C +Cc1nn(CC(N)=O)c(C)c1-c1ccc(C2CCCC2)cc1 +COC(=O)CC(Cc1ccc(F)cc1)C(=O)OC +COc1ccc2oc(C(=O)N(C)Cc3ccc(C)o3)c(C)c2c1 +CCn1nc(C)c(CN(C)C(=O)c2cc(-c3cccs3)on2)c1C +O=C(NCc1ccc(Cl)cc1)NCC1CCC1 +COc1ccccc1CNC(=O)c1cc(Cl)c(O)c(OC)c1 +CCC(OC)C(=O)N1CCN(c2ccccc2C)C(=O)C1 +O=c1[nH]c2ccccc2c(=O)n1CCCOCC1CCOC1 +CS(=O)(=O)Oc1ccc2c(-c3ccccc3)cc(=O)oc2c1 +Cc1nc2ccccc2n1CC(=O)NC(C)c1cc2ccccc2o1 +CC1CCC(C)N(C(=O)Nc2cc(Br)cn(C)c2=O)C1 +CN1C(=O)Cc2cc(NC(=O)NCc3ccc(F)cc3)ccc21 +O=C(Nc1cc[nH]n1)c1cc(Cl)cc2cccnc12 +Cc1noc(C)c1CCCNC(=O)Nc1cccc2cccnc12 +Cc1cc(CN2CCN(C(=O)c3cccc4cn[nH]c34)CC2)on1 +CCCc1nc(CN2CCN(C(=O)c3cccc(OC)c3)CC2)no1 +CCC(O)c1cc2c(cc1NC(=O)c1ccc(C)cc1)OCCO2 +Cn1c(NCc2cnn(-c3ccccc3)c2)c(C#N)c(=O)n(C)c1=O +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)COc1ccccc1 +COc1ccc(C(=O)N2CCN(CCO)CC2)cc1F +Cc1nnc2n1CCN(CCOc1ccccc1C#N)C2 +N#Cc1ccc(N2CCC(C(=O)N3CCCCC3)CC2)nc1 +Nc1ccc2[nH]c3nnc(-c4ccc(F)cc4)n3c2c1 +CCCNC(=O)Nc1ccc(CC(=O)N2CCOC(CCC)C2)cc1 +Cc1cc(C(=O)N2CCOCC(CO)C2)sc1-c1ccccc1 +Cn1c(SCCc2ccccc2)nnc1C(F)(F)F +COc1cc(C)sc1C(=O)NCCCNC(=O)c1cccs1 +Cc1c(C(=O)NCCN2CCOCC2)oc2c1-c1[nH]ncc1CC2 +Cc1nn(C)c(C)c1OCc1nsc(N(C)C)n1 +O=C1CCSc2c1cccc2C(=O)N1CCC(c2ccccc2)C1 +CC(C)n1cnnc1CN(C)C(=O)C1CCN(C(=O)C2CCC2)CC1 +N#CCCN(CCC#N)C(=O)Cc1cccc(N)c1 +CCNC(=O)CNC(=O)C1(C)Sc2ccccc2NC1=O +Cc1ccccc1NC(=O)c1csc(-c2ccc(C)n2C)n1 +O=C(NCCn1ncc2ccccc2c1=O)c1ccc(F)c(F)c1 +N#Cc1cc(C(F)(F)F)ccc1N(CCO)Cc1cccnc1 +CC(=O)NC1CCCN(C(C)C(=O)Nc2ncccn2)C1 +CN(C)C(=O)c1ccccc1NCC(=O)N1CCCCC1 +CCn1ccc(CNC(=O)CCn2cc(Br)c(C)n2)n1 +COCCN(CC(C)C)C(=O)Cc1ccc(Cl)cc1 +CC(NC(=O)N1CCc2ccccc21)C1CCCO1 +CC(=O)Nc1ccc(S(=O)(=O)NCC(C)(O)C2CC2)cc1 +O=C(NCc1ccc(C(F)(F)F)cc1)c1cc(=O)nc2cccnn12 +CC1Sc2ccc(C(=O)NCCc3cccc(F)c3)cc2NC1=O +CCCC1CN(Cc2ccc(Oc3cnccn3)cc2)CCO1 +COC(=O)c1sc(NC(=O)C2CC2C)nc1C1CC1 +O=C(NCCO)c1cc2ccccc2cc1NC(=O)C1CC1 +O=C(NCCc1ccccn1)C1CC(=O)N(C2CCCC2)C1 +CC(C)(C)C(CO)Nc1ccc(S(C)(=O)=O)cc1S(C)(=O)=O +COc1ccc(S(=O)(=O)NC(C)c2cccnc2)c2cccnc12 +COc1ccc2c(c1)C(Cc1ccccc1)C(=O)CC2 +CC(C)CCNC(=O)c1cc(N)cc(S(C)(=O)=O)c1 +c1ccc(-c2nnc(C3CCN(Cc4ccc5c(c4)OCO5)C3)o2)cc1 +C=CCNc1nnc(SCC(=O)N(C)C2=CCCC2)s1 +OCCn1ncc2c1CN(c1nc3ccccc3o1)C2 +NC(=O)CNC(=O)CCc1ncc(-c2ccc(F)cc2)o1 +COC(=O)CNC(=O)CNC(=O)c1ccc(C(C)(C)C)cc1 +Nc1cc(F)cc2c(C(=O)NCCCO)nccc12 +COc1ccc(C(=O)NCC(C(C)C)N2CCOCC2)cc1 +CCNC(=O)NC1CCN(C(=O)CC(C)C)CC1 +Cc1ccc(N)cc1C(=O)NCC1CCCCC1C +CCS(=O)(=O)NC(C)C(=O)N1CCOCC1 +CSc1ccc(Cl)c(C(=O)N2CCCCC2C)c1 +Nc1cc(S(=O)(=O)NC2CC2)c(Cl)cc1F +O=C(NCCc1ccco1)c1ccc2c(c1)CCN2 +Cc1cc(C)nc(SCC(=O)Nc2cc(F)ccc2C)n1 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+CCOC(=O)c1ncsc1N(C)C(=O)c1cnc(C)s1 +N#Cc1ccc(C(=O)NCC2(N3CCOCC3)CCCCC2)cc1 +Cc1cc(=O)c(CC#N)nn1-c1ccccc1Br +Cc1noc(-c2ccc(C(=O)NCCN3CCOCC3)cc2)n1 +Cc1ccc(Sc2ncnc(N3CCCCC3)c2N)cc1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)c1cc(Cl)ccn1 +Cc1ccc2nc(C)c(C(=O)N=c3[nH]nc4ccccn34)cc2c1 +COCCCNC(=O)Cn1nc2c(cc1=O)CCCC2 +Cc1cc(C(F)F)c2c(N)c(-c3ccccn3)sc2n1 +CN(C(=O)c1cccc(OCC(F)F)n1)C1C2CCOC2C1(C)C +O=C1COc2cc(C(=O)N=c3[nH]nc4ccccn34)ccc2N1 +CC(C)c1ccc(OC(=O)CN(C)S(C)(=O)=O)cc1 +CCCCN(CCOC)C(=O)Nc1ccc2c(c1)oc(=O)n2C +O=C1CC2CCC(CN1)N2C(=O)OCc1ccccc1 +CCCCSc1nnc2n(C)c(=O)c3sccc3n12 +O=C(Nc1ccc(CN2CCOC2=O)cc1)N1CCCC1 +Cc1ccc(-c2nnc(C(C)Sc3ncccn3)o2)cc1 +COc1ccc(C(=O)N2CCC(Nc3cccnc3)C2)cc1F +Cn1c(=CC(=O)C(C)(C)C)sc(=Cc2ccccc2F)c1=O +COCCCNC(=O)Nc1cc(NC(=O)C2CC2)ccc1C +COc1cc(F)ccc1N1CCN(Cc2ccon2)CC1 +Cc1cc(OCC(=O)N2CC(O)C2)ccc1Cl +Cc1cccc(OCCNC(=O)Cc2cccc3cccnc23)c1 +Nc1n[nH]c2nc3c(c(-c4ccccc4)c12)CCC3 +Cc1ccc(-n2nc(C)cc2NC(=O)C2CCOC2)nn1 +COC(=O)c1ccc(Nc2ncc(N)cc2OC)cc1 +CCc1nnc(SCC(=O)Nc2ccc(C)c(Cl)c2)n1N +Cc1nnc(NCC(=O)NC(C)(C)C)c(C#N)c1C +CC(=O)c1ccc(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)cc1 +Cc1cc(C)cc(NC(=O)Cn2nnc(-c3ccc(F)cc3)n2)c1 +CCSc1ncc(CO)n1Cc1ccc(OC)cc1 +O=C(CCC(=O)Nc1nccs1)N=c1[nH]nc2ccccn12 +CCc1cccc(NC(=O)c2cc(CN3CCOCC3)on2)c1 +CCOC1CCN(C(=O)NCc2cn3cc(Cl)ccc3n2)CC1 +COc1ccnc(NC(=O)c2ccc(C(=O)NC3CC3)cc2)c1 +CCCCc1nc2c(sc3nc(C)cc(COC)c32)c(=O)n1N +C=CCC(C#Cc1ccc(C)cc1)N1CCOCC1 +CCn1nc(-c2cc(F)ccc2F)cc(N)c1=O +COc1ccccc1CCC(=O)c1cccc(N)c1 +Cc1nc(-c2nnc(NC(=O)NCc3ccccc3)o2)cs1 +CCC1(CC)C(NC(=O)c2cccc3c2oc(=O)n3C)C(C)C1OC +COc1ccccc1-c1nnc2c(C)cc(N)cn12 +COc1cc(C#N)ccc1CNc1nnc(C)s1 +O=C(Cc1cccs1)Nc1nnc(C2CCCCC2)o1 +COc1ccc(OC)c(C(=O)N2CCC3(CC2)OCCO3)c1 +O=C(Nc1nncs1)c1cc2ccc(OC(F)(F)F)cc2[nH]1 +CCOCC(=O)N1CCC(C(O)c2ccc(F)cc2)CC1 +CCN(Cc1cccc(C)c1)C(=O)C1CC(=O)N(Cc2ccco2)C1 +CCCC(C)N1CC(C(=O)Nc2ccccc2OC)CC1=O +O=C(Nc1nnc(C2CCCCC2)s1)c1cccc(F)c1F +Cn1cc(C(N)=O)cc1C(=O)OCc1nnc(-c2ccccc2)o1 +CCOc1ccc(F)c(C(=O)N2CCC(=O)Nc3ccccc32)c1F +O=C1OCC(Cc2cccc(O)c2)C1Cc1cccc(O)c1 +COc1nn(-c2ccccc2)cc1Br +O=C(NCC1CN2CCCCC2CO1)Nc1cc(Cl)ccc1F +Cc1nc(CCNCc2csc(-c3ncccn3)n2)cs1 +Cc1ccc(OC2CCN(C(=O)Cc3c(C)noc3C)CC2)cn1 +COCc1cc(C)nc2sc(C(=O)Nc3nccs3)c(N)c12 +COc1cc(CNC(=O)CCN2C(=O)CCc3ccccc32)ccn1 +Cn1c(=O)c2nc(SCc3ccccc3F)n(C)c2n(C)c1=O +Cc1nc(CSc2ccccn2)nc2ccccc12 +Cc1cccc(NC(=O)NC(C)c2ccccn2)c1 +O=C(CSc1ccc(-c2cccs2)nn1)Nc1cccnc1 +CC(C)N(CCC#N)S(=O)(=O)CCc1ccccc1 +Cc1noc(CNC(=O)NC2CCOC2c2ccc(Cl)cc2)n1 +CCc1noc(CC)c1CNC(=O)Cc1ccc(C)cc1 +CC(O)(CNS(=O)(=O)c1ccc(F)c(Cl)c1)c1ccccc1 +CC(C)(C)Nc1ncnc(Nc2cc(F)ccc2F)c1N +N#Cc1cc(F)ccc1NCC1CCN(S(=O)(=O)C(F)F)CC1 +O=C(CSc1nnc(Cn2cncn2)o1)c1ccc2c(c1)CCO2 +O=C(Nc1cccc(Oc2ncccn2)c1)c1ccccc1 +CCN1CC(C(=O)NCc2cccc(-c3ccccc3)c2)CC1=O +O=C(CSc1nc(C2CCCO2)n[nH]1)Nc1cccc(F)c1 +CCOC1CCCN(C(=O)c2c(C)cccc2N)C1 +CCc1cc(C(=O)Nc2sccc2C(=O)NC2CC2)sc1C +CN(Cc1cc(Cl)cc(Cl)c1)Cc1ccnn1C +Cc1cc(NC(=O)N(Cc2ccco2)C2CC2)n(C)n1 +O=C(CC1C(=O)Nc2ncnn21)Nc1cccc(F)c1 +O=C(NC1CCSc2ccc(Cl)cc21)N1CCCC(CO)C1 +Cc1nn2cccnc2c1C(=O)N(C)Cc1nc2ccccc2n1C +CN(CC(=O)Nc1ccn(C)n1)c1ccc(Cl)cn1 +Cc1ccc2c(c1)CCCN2CC(=O)N1CCCC1 +CCc1nc2n(n1)CCCC2NC(=O)COc1ccc(C(C)C)cc1 +O=C(c1cc(C2CC2)n[nH]1)N1CCCC(c2nc3ccccc3[nH]2)C1 +COCCNC(=O)CNC(=O)C1(c2cccc(Cl)c2)CC1 +CCN(CC)C(=O)Cn1c(CC#N)nc2cc(F)ccc21 +O=C(c1cccnc1)N1CCOc2ccc(Cl)cc21 +O=C(NC1CCCCC1)N1CCC(Oc2cccnn2)CC1 +CCCC1CN(C(=O)c2ccc(C)c(C)c2)CCO1 +COC(=O)c1cc2ncc(Br)cc2n1C +CCCC(C)C(=O)NCCC(=O)N1CCN(c2ccccc2)CC1 +Cc1ccsc1CNc1cncc(-n2cccn2)n1 +Cc1cccc(OCCn2nnc(CO)c2-c2ccccc2)c1 +NC(=O)c1csc(C(=O)OCc2cccc(F)c2)c1 +CN(CCNS(=O)(=O)Cc1ccc(F)cc1)c1ccccc1 +COc1cc(-c2nccnc2C#N)c(OC)cc1C +COC(C)(C)c1noc(C2CC2c2ccc(Cl)cc2)n1 +O=C(c1ccco1)N1CCN(c2ccccc2)CC1 +COc1ccc(C(NC(=O)c2cccnc2)C2CC2)cc1 +CCc1cc2c(=O)[nH]c(CC(=O)Nc3ccccc3OC)nc2s1 +Cn1c(N)nnc1SCCCOc1cccc(Cl)c1 +Nc1cc(NC2CCC(O)CC2)nc(SCc2ccccc2)n1 +Cc1cc(C)n(-c2ccc(NC(=O)NCc3cccc(C#N)c3)cn2)n1 +CCOc1ccc2c(c1)CN(C(=O)Nc1c(C)noc1CC)CC2 +COc1cccc(OC)c1C(=O)NCc1cn2cc(Cl)ccc2n1 +C=CCC(=O)N1CCC2(CCCN(Cc3cccc(OC)c3)C2=O)C1 +CCCOCC(=O)Nc1ccc2c(c1)oc(=O)n2C +CCNC(=O)c1cccc(NC(=O)COC(=O)c2ccccc2)c1 +O=C(Nc1cccc(Cl)c1)C1(n2cnnn2)CCCCC1 +COc1ccc(OC)c(-n2nnc(CO)c2C2CCCO2)c1 +Cc1nnc(SCC(=O)Nc2ccc(OC(F)(F)F)cc2)o1 +CCC(C)OCCCC(=O)Nc1cccc(C#N)c1 +O=C(NCC(=O)N1CCN(c2ccccc2O)CC1)c1cccs1 +CCOCCC(=O)N1CCCCC1Cn1cc(C)cn1 +COCC(NC(=O)c1cn(C)nc1C(C)(C)C)C(N)=O +Cc1ccc(OCCNS(=O)(=O)c2c(C)noc2C)cc1 +COC(=O)C1=C(C)N(C(C)C)C(=O)NC1c1cccc(OC)c1 +Cc1ccc(F)cc1NS(=O)(=O)c1ccc(C#N)cc1 +COc1cc(C)ccc1OC(=O)CCC(=O)c1ccc(F)cc1F +Cc1cccc(C)c1NC(=O)c1c(F)c(F)c(F)c(F)c1F +CC(OCc1ccccc1)C(=O)NC1c2ccccc2CC1O +COc1cc(NC(=O)Cc2c(C)noc2C)ccc1N1CCCC1=O +Cc1ccsc1-c1nccn1Cc1cn2ccsc2n1 +O=c1c2ccccc2nc2n1CCC2=Cc1ccc(O)cc1 +CCn1nc(C)cc1C(=O)NCC(=O)NCCc1ccccc1Cl +O=S(=O)(Cc1cccc(OC(F)F)c1)c1ccc(O)cc1 +COc1ccnc(Oc2ccc(NC(C)=O)cc2)c1C#N +CCC(=O)N1CCN(Cc2cc3cc(F)ccc3o2)CC1 +O=C(Oc1ccc(CN2CCOCC2)c2cccnc12)c1ccco1 +COC(=O)C1CCCC1NC(=O)Nc1cccc(C)c1C +CCCN(CCO)C(=O)Nc1cc(C(F)(F)F)ccc1N(C)C +CCOc1ncccc1C(=O)N1CCCC1Cn1nc(C)cc1C +O=C1CCC(C(=O)Nc2ccc(NC(=O)Nc3ccccc3)cc2)N1 +CCOc1ccccc1C(=O)N1CCN(C(=O)c2csnn2)CC1 +O=S1(=O)N=C(NCc2ccccn2)Nc2ccc(F)cc21 +CC(O)CC(C)CNC(=O)c1csc(-c2cnn(C)c2)n1 +CC(OC(=O)Cn1ccc(=O)n(C)c1=O)c1cccc(F)c1 +COc1c(C(=O)NC2CCSc3ccc(C)cc32)c(C)nn1C +Cc1ccc(NC(=O)N2CC(C)CC(C)C2)c(OCC(=O)N(C)C)c1 +Cc1cc(C)n(Cc2noc(-c3ccco3)n2)c(=O)c1C#N +Nc1cccc2c1N(C(=O)Cc1ccccc1)CCC2 +Cn1nnc2c1C(COCC1CC1)CN(C(=O)Cc1ccccn1)C2 +O=C(Cc1noc(-c2cscn2)n1)NC1CCCCC1 +Cc1oc(-c2cccs2)nc1C(=O)Nc1cc[nH]n1 +O=C(c1ccoc1)N1CCN(c2nnc3c(Cl)cccn23)CC1 +N#Cc1cccc(NC(=O)c2ccc(S(=O)(=O)C(F)F)cc2)c1 +CCCCCc1nnc(NC(=O)c2cccnc2)s1 +CCCNC(=O)CNC(=O)Nc1ccc(C)cn1 +Cc1cc(N(C)C)nc(CNC(=O)Nc2cccc(Cl)c2)n1 +CC(=O)N1c2ccccc2C(=O)C1N1CCN(c2ccccc2)CC1 +O=C(COc1ccccc1)Nc1cnc(-n2cccn2)nc1 +COc1ccc(Cl)cc1NCc1nc(C)c(C(C)=O)s1 +CNC(=O)CSc1ccc(-c2ccncc2)nn1 +Cc1nn(-c2ccc(NC(=O)c3ccco3)cn2)c(C)c1Cl +N#CCC(COc1ccc(F)c(F)c1)N1CCCC1 +Cc1ccc(OC(C)C(=O)Nc2ccc(N)cc2C)cc1 +CC(C)CN(C)C(=O)Nc1cccc2c1OCCO2 +COc1cccc(NC(=O)C2CCCN(S(=O)(=O)N(C)C)C2)c1 +N#CCCN(C(=O)Cc1cccs1)c1ccc(F)cc1 +CCC(=O)N(Cc1cc(=O)[nH]c2ccccc12)c1ccc(C)cc1 +CCOC(=O)C1CCN(C(=O)Nc2ccc3oc(C)nc3c2)CC1 +COc1ccc(S(=O)(=O)Oc2cccc(F)c2)cc1C +CCn1c(C(=O)NC(C)c2ccccc2)nc2ccccc21 +CCOC(=O)C(N)c1ccc(C2CCCCC2)cc1 +COc1cc(N2CCCC(C(=O)c3ccccc3OC)C2)ncn1 +N#CC1(NCc2ccc3c(c2)OCO3)CCCCC1 +CCN(Cc1ccccc1)C(=O)CSc1nnc(-c2ccco2)o1 +N#CCCn1c(CC(F)(F)F)nc2ccc(F)c(F)c21 +COc1ccccc1CNC(=O)c1cc(C)nc2c1c(C)nn2C +CCOCCOc1ccc(Cl)cc1NC(=O)c1ccnnc1 +N#Cc1cccc(COC(=O)C(O)(c2ccccc2)c2ccccc2)c1 +CCOc1ccc(NC(=O)NCC2(CO)CC2)cc1 +N#Cc1ccc(CCC(=O)Nc2ccc(N3CCOCC3)nc2)cc1 +O=C(CCC(=O)N1CCOc2ccccc21)NCc1cccnc1 +CC(NC(=O)NCc1cccnc1OC1CCCC1)c1nncn1C +Cc1ccnc2nc(C(=O)NCc3nc4ccccc4s3)nn12 +CC(Nc1cccc(NC(=O)CO)c1)C(=O)N1CCc2ccccc21 +Cc1ccccc1OCc1nnc(SCC(=O)N2CCCCC2)o1 +COc1cccc(OCC(=O)Nc2ccc(S(C)(=O)=O)cc2)c1 +Nc1ccc2nc(NC(=O)CN3CCCC3=O)sc2c1 +C#CCN(Cc1cnc(C)cn1)Cc1cccc(C)n1 +CC(C)N(CCO)C(=O)c1ccc(O)c(Cl)c1 +CN(C)S(=O)(=O)c1c[nH]c(C(=O)Nc2nccs2)c1 +Cc1ccc2nc3c(cc(C(=O)N(C)CCC#N)n3C)c(=O)n2c1 +CNC(=O)C1CC2CN(S(=O)(=O)c3ccccc3C)CC1O2 +Cc1ccc(C(=O)NCCCC(=O)Nc2ccc(F)cc2)cc1 +COC(=O)c1cc(S(=O)(=O)Nc2c(C)n[nH]c2C)ccc1F +CC(C)CN1C(=O)CCc2cc(NC(=O)c3ccc(F)cc3)ccc21 +COc1ccc(CCC(=O)Nc2cccc(C(C)=O)c2)cc1 +Oc1nc2c(n1CCN1CCOCC1)NCCC2 +COc1cc(C(=O)NC(C)c2ccc(NC(N)=O)cc2)ccc1C +O=C(Nc1ccncc1)c1cccc(NC(=O)c2cc(Cl)c[nH]2)c1 +CCNC(=O)NCCn1nc(C(F)(F)F)n(C)c1=O +COc1ccc(F)c(NC(=O)Cn2c(=O)[nH]c3ccccc3c2=O)c1 +CCOC(=O)CC1NCC2c3ccccc3CCN2C1=O +CCC(C)C(C)(O)CNC(=O)c1cccc(OC)c1OC +COCC(c1ccccn1)N(C)Cc1ccnc2ccccc12 +CS(=O)(=O)c1ccccc1C(=O)NCCOc1ccccc1 +CCCC1CN(C(=O)C2CCCN(C(N)=O)C2)CCO1 +N#CCCn1cc(C=Cc2nc(-c3ccncc3)no2)c2ccccc21 +Cc1cc(C)n(-c2cncc(N3CCC(c4nncn4C)CC3)n2)n1 +CSc1nnc(Cn2c(=O)sc3ccccc32)n1C +CCCCN(C)C(=O)c1ccccc1SCC(=O)N1CCCC1 +Cc1ccncc1NC(=O)N1CCC2OCCCC2C1 +O=C(Nc1nc2c(s1)CN(C(=O)C1CC=CCC1)CC2)C1CCC1 +CNC(=O)c1cccc(NC(=O)Cn2cc(Cl)cn2)c1 +COCCOc1ccc(C(F)(F)F)cc1NC(=O)C1CCC(=O)N1 +CN(Cc1ccccc1N)CC(O)c1ccccc1 +CC(C(=O)c1ccc2c(c1)CCCN2)N1CCC(C(N)=O)CC1 +Cc1ccn(-c2ccc(N3CCCC(CN4CCOCC4)C3)nn2)n1 +CCc1cc2c(NCCC(=O)NC3CC3)ncnc2s1 +Cc1nc2cc(NC(=O)CCC(=O)c3ccc4c(c3)CCC4)ccc2o1 +CCCS(=O)(=O)NC(c1ccc(OC)cc1)C1CCOCC1 +Cc1ccc2cccc(Oc3ncnc(N4CCCCC4)c3N)c2n1 +COc1cccc(-c2nc(-c3cc(N)cc(N)c3)n[nH]2)c1 +CCCS(=O)(=O)Nc1ccc(CC(=O)N2CCCC2)cc1 +CC1(CCc2ccccc2)OC(=O)N(Cc2ccccn2)C1(C)O +CCCCN(C)S(=O)(=O)NC1CCCC(C)C1C +CCOC(=O)c1cnc(SCC(=O)N(C)c2ccccc2)nc1N +CS(=O)(=O)N1CCCC1c1ccnc(Nc2ccccn2)n1 +Cc1noc(C)c1C(=O)N1CCCC(c2cc3ncccc3cn2)C1 +O=C(OCC(=O)N1CCN(c2ccccc2F)CC1)c1cccs1 +Nc1nc(-c2ccccc2)nn1C(=O)c1cccnc1 +Cc1nn(C)c(C)c1CC(C)NC(=O)NC1c2ccccc2CC1O +CC(OCC1CCCO1)C(=O)N(C)C1CCc2ccccc2C1 +O=S(=O)(NCc1cccn1Cc1ccccc1)c1ccc(F)cc1 +CN(C)c1nc(N)nc(COC(=O)c2cc(Cl)ccc2F)n1 +Cc1nn(-c2ccccc2)cc1CCCNS(C)(=O)=O +Cc1csc(N2CCN(C(=O)Nc3cccnc3)CC2)n1 +O=C(NCC1Cc2ccccc21)c1ccnc(-n2cncn2)c1 +CC1Oc2ccccc2N(CC(=O)NCc2cc3ccccc3[nH]2)C1=O +CN(CC1CC1)C(=O)Nc1cc(C(F)(F)F)ccc1N(C)C +Cc1sc2ncn3nnnc3c2c1-c1ccc(Cl)cc1 +CC(C)c1cccc(CNc2cccc(CO)c2)n1 +CCCN1C(=O)C(C)S(=O)(=O)c2ccc(N)cc21 +Cn1nccc1NC(=O)c1cc2ccccc2oc1=O +CCCCOc1nc(C)nc(NC2CCCCC2C)c1N 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+Cc1nc(C#N)c(C#N)n1Cc1cc(F)ccc1C#N +Cc1cnc(C(=O)NC(C)c2nnc3n2CCCCC3)cn1 +Cc1noc(C2CCN(C(=O)c3cc4ccccc4n3C)CC2)n1 +CNS(=O)(=O)CC(=O)NC(c1ccc(Cl)cc1)C(C)C +CC(CN(C)c1ccccc1)NC(=O)C1COCCO1 +CCC(C)NS(=O)(=O)c1cccc(C(C)=O)c1 +Cc1ccc(NC(=O)Nc2cnn(CC3CCCO3)c2)cc1Cl +CC(C)(C)CCNC(=O)CN1CCN(S(C)(=O)=O)CC1 +COc1ncccc1C(=O)NCc1nncn1C(C)C +CCCCCNC(=O)Cc1cn(C)c2ccccc12 +COc1ccc(-n2ccc3nc(N4CCCC4)ncc3c2=O)cc1 +Cc1cccc(S(=O)(=O)CCCn2ccc3occc3c2=O)c1 +CC1=C(C(=O)Nc2ccccc2)C(c2ccccc2C)NC(=O)N1 +Cc1nc2ncn(-c3ccccc3)c2c(=O)n1-c1ccccc1 +Cc1ccccc1CN(C)C(=O)NC(c1nnc2n1CCC2)C(C)C +COc1ccc2ncc(-n3ccnc3-c3ccccn3)cc2c1 +COc1ccc(C(=O)Nc2nc3ccccc3[nH]2)cn1 +CC1=C(Cc2cn(CC(O)c3cccnc3)nn2)C(C)(C)CCC1 +COC(C)(CNS(=O)(=O)c1cccs1)c1ccccc1F +COC(=O)CCSc1nnnn1C1CCCCC1 +COc1ccccc1OCC(=O)Nc1ccc(-n2cnnn2)c(C)c1 +COCC1CN(S(=O)(=O)c2ccccc2)Cc2ncnn2C1 +CN(CCC(F)(F)F)C(=O)CNC(=O)c1ccc(F)c(F)c1 +O=C(Cn1ccnc1)N(Cc1ccc(C(F)(F)F)cc1)C1CC1 +CCN(CC(=O)Nc1c(C)n[nH]c1C)C(C)c1ccc(C#N)cc1 +CCC(C)N(CCOC)S(=O)(=O)c1c[nH]nc1N +CCOc1ccccc1N1CCN(C(=O)C(C)n2cncn2)CC1 +Cc1cc(NC(=O)NCc2cc(C)c(O)c(C)c2)n(C)n1 +CCOc1cc(CNc2ccc(C)cn2)ccc1O +CN(Cc1cccc(Cl)c1)C(=O)c1ccccc1O +CNc1nnc(-c2cc3c([nH]c2=O)CCN(C)C3)s1 +CC(C)CC(=O)N1CCc2nc(-c3ccccc3)ncc2C1 +CCC(Sc1nnc(C2CC2)n1C)c1ccccc1 +CC(c1ccccc1)n1cnnc1SCCC(N)=O +O=C(Nc1ccc(F)cc1)c1ncoc1-c1cccs1 +CCc1cc(N2CCN(Cc3cccc(C)c3)C(=O)C2)n2nccc2n1 +CCn1nnc2cc(C(=O)N3CCc4ccccc43)ccc21 +O=C(NCCCO)c1cc2cccc(Br)c2o1 +Cc1nc(C)c(CNC2CCN(c3ccccc3)C2=O)s1 +Cc1nc(-c2ccncc2)sc1C(=O)c1ccccc1 +COc1cccc(CNS(=O)(=O)c2ccc3c(c2)CCC3)c1OC +CCc1ccc(C(=O)OCc2ccnc(C#N)c2)o1 +CCOC(=O)C1CCCN1C(=O)CCC1CCCO1 +Cc1cc(=O)oc2cc(Oc3c(C#N)c(=O)n(C)c(=O)n3C)ccc12 +CC(C)CCn1c(SCC(O)CO)nc2ccccc2c1=O +CCCS(=O)(=O)Nc1ccc(N2CCCS2(=O)=O)cc1 +CC(=O)Nc1nc(CC(=O)N2CCC(C(N)=O)CC2)cs1 +COC(=O)C1CCCC1NC(=O)Nc1ccc(CC#N)cc1 +Cc1ccc(CNC(=O)c2csnn2)c(N(C)C)c1 +CC(C)c1cc(C(=O)N2CCC(CO)C(O)C2)cs1 +CC(C)NC(=O)C1CC(=O)N(Cc2ccccn2)C1 +COCCCC(=O)N1CCN(Cc2cc(C)on2)CC1 +Cc1ccc(OCC#CCNC(=O)NCc2ccc(Cl)cc2)cn1 +Cc1ccc(F)cc1NC(=O)c1ccc(CNC(=O)NC(C)C)cc1 +COc1ccc(F)c(NC(=O)CCOCC(C)C)c1 +COCC(=O)N1CCC(c2cc3ncccc3c(=O)[nH]2)CC1 +CCS(=O)(=O)NCCCNC(=O)c1cc(C)ccc1O +CC(C)CNC(=O)C1CC2CN(S(C)(=O)=O)CC1O2 +CC(CNC(=O)c1cc(C2CC2)nc2ccccc12)Cn1cccn1 +N#CCSc1ccccc1C(=O)Nc1cccnc1 +NC(=O)CCC(=O)c1ccc2c(c1)-c1ccccc1C2 +O=C(Cc1ccon1)NCc1csc(CCc2ccccc2)n1 +O=C(CC1(N2CCOCC2)CCCC1)Nc1ccc(CCO)cc1 +COc1cc(C#N)ccc1OCC(=O)N(C)C(C)c1cccnc1 +CCn1nccc1CNC(c1ccc(Cl)cc1)c1ncon1 +COC(=O)C(C)N1C(=O)C(C)Nc2cc(C)ccc21 +Cc1csc(C(C)(C)NCC(=O)N(C)CC(F)(F)F)n1 +CCCCC(c1cccnc1)N(C)C(=O)Nc1c(C)nn(CC)c1C +NC(=O)CCN(C(=O)c1ccncc1F)c1ccc(F)cc1 +N#Cc1cc2cc(Cl)cnc2nc1N1CCCCC1 +CC(=O)Nc1cccc(CSc2nccn2Cc2ccccn2)c1 +Cc1ccc2c(c1)nc1[nH]c(NCc3ccc(F)cc3)nn12 +NC(=O)c1ccc(CNC(=O)Cc2c(F)cccc2F)o1 +CCC(=O)Nc1cc(-c2ccco2)nn1-c1nc(C)c(CC)c(=O)[nH]1 +O=C(NCc1ccco1)C1CCCN(C2=NC=NC3=NC=NC32)C1 +CCCC(=O)N1CCN(C(=O)NCCNC(C)=O)CC1 +CCC(OC)C(=O)NCc1cn2cc(Br)ccc2n1 +CC1CCN(c2nc(-c3ccccc3)cc(=O)[nH]2)CC1 +CC(C)(C)CC(=O)Nc1ccc(C#CCO)cc1F +O=C1CCC(COC(=O)c2csc(-c3ccccc3)n2)N1 +O=C(NCc1nncn1C1CC1)C1(c2cccs2)CCCCC1 +COCCNC(=O)c1ccccc1NS(=O)(=O)c1ccccc1 +Cn1cnc(CNC(=O)c2ccc(-n3cnc4ccccc43)nc2)n1 +CCC(C#N)S(=O)(=O)N1CCN(Cc2nc(C)c(C)o2)CC1 +COc1ccc(OC)c(N2CCn3c2nc2c3c(=O)[nH]c(=O)n2C)c1 +O=C(COc1ccc(F)cc1F)NCCOc1ccccc1 +Cc1ccc(C)c(CSc2nc3c(=O)n(C)c(=O)n(C)c3n2C)c1 +COc1cc(NC(=O)CCc2cccs2)cc(OC)c1OC +Cc1ccc(F)cc1NS(=O)(=O)c1c(C)n[nH]c1C +COc1ccc(Cl)cc1NS(=O)(=O)c1cccc(C(N)=O)c1 +Cc1ccc2c(c1C)OCC2NC(=O)NC(C)C(=O)NC(C)(C)C +Cc1nnnn1-c1nc(-c2ccc(F)cc2)cc(C(F)(F)F)n1 +CN(c1ccccn1)S(=O)(=O)c1ccccc1C(F)(F)F +CCOC(=O)COc1cccc(NC(=O)c2ccccc2F)c1 +Cc1cccc(NC(=O)C2CC=CCC2C(=O)N2CCCCC2)c1 +COCCNC(=O)c1sc(N(Cc2ccccc2)C(C)=O)nc1C +O=c1cc(N2CCC3(CC2)OCCO3)[nH]c(=O)n1C1CCCCC1 +CNC(=O)Cc1ccc(NCc2ccc(Cl)c3cccnc23)cc1 +CC(=O)NCCC1CCCN(c2ccnc(C)n2)C1 +CC(C(=O)NC1CC1)S(=O)(=O)c1nnc(N2CCCC2)s1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)N(C)Cc1cnn(C)c1 +Cc1ccsc1CNC(=O)Nc1ccc2c(c1)OCC(=O)N2 +CNC(=O)Cc1ccc(NC(=O)NCc2cccc(OC)c2)cc1 +O=C(NCCc1ccco1)Nc1ccc(F)cc1F +Cc1cccc(NC(=O)NCc2nccc(N(C)C)n2)c1C +Cc1cc(CN2CCN(C(=O)c3cc(C)c(C)s3)CC2)on1 +COc1cccc2cc(-c3csc(NC(=O)c4ccco4)n3)oc12 +Cc1oc(-c2cccs2)nc1CC(=O)N(C)CC(N)=O +COC(=O)c1cc(C(=O)Nc2ccccc2O)n(-c2ccccc2)n1 +COc1cccc(NCc2ccc3c(c2)CCO3)n1 +Cc1nnc(CNc2ccccc2OC(F)F)n1C +N#Cc1ccc(OC2CN(C(=O)NC3CC=CC3)C2)cc1 +O=C(NCc1cc(=O)[nH]c(-c2ccccn2)n1)c1ccccc1F +NC(=O)c1c(NC(=O)c2c(F)cccc2F)sc2c1CCCC2 +COc1ccc(Cl)cc1C(O)CNCc1ccccn1 +COc1ccc(-c2c(C)c3ccccc3[nH]c2=O)cn1 +Cc1cc(C)nc(NC(=O)c2ccncc2Cl)c1 +COc1ccc(CO)cc1OCc1ccccc1F +CCC(=O)N1Cc2ccc(C(O)c3ccc(F)cc3)cc2C1 +Cc1ccc(S(=O)(=O)C2(C(=O)NCc3cc[nH]n3)CCC2)cc1 +NC(=O)Nc1ccc(NC(=O)c2cnc3ccccn3c2=O)cc1 +COc1ccncc1NC(=O)c1cc(=O)c2ccccc2o1 +CCc1ccc(C(=O)Nc2c[nH]cc(Br)c2=O)o1 +Cc1cc(N)c2ccnc(C(=O)N3CCOCC3)c2c1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)N3CCCCC3)C2)cc1 +Cc1noc2ncc(C(=O)N3CCc4sccc4C3C)cc12 +Cn1cc(Br)c(C(=O)Nc2nc3ccccc3s2)n1 +CCOC(=O)C1CCCN(c2ncc(N)cc2OC)C1 +COC(=O)N1CCCC(C(=O)N(CC(F)(F)F)C(C)C(C)C)C1 +CC(Sc1ncn[nH]1)c1ccc(OC(F)F)cc1 +CS(=O)c1ccc(C(=O)Nc2nc(C3CC3)cs2)cc1 +COc1ccccc1NCC(=O)Nc1nnc(C(C)C)s1 +Cc1cc(C(=O)NCc2nn(C)c3c2CCCC3)no1 +CC1(NC(=O)NCc2ncccc2F)Cc2ccccc2C1 +COC(=O)Cc1ccccc1Cn1ccc(C)c(C#N)c1=O +COc1ccc(Cl)c(NCC(=O)N2CCN(C(C)=O)CC2)c1 +COc1cc2nc(-c3ccc(C)cc3)n(CCCO)c2cc1OC +O=C(COc1ccccc1)Nc1cc(F)ccc1F +O=C(NCc1cscn1)c1nn(-c2ccccc2F)c2c1CCC2 +COc1ccc(-n2ncc(C(=O)NCCc3ccccn3)c2C)cc1 +CC1CCN(C(=O)C(C#N)CCc2ccccc2)CC1 +COc1ccc(F)c(NCC(=O)N(C)c2ccccc2)c1 +CC(=O)Nc1cccc(OCC(=O)NC(C)C)c1 +COCc1ccccc1CNC(=O)CC1CCCCC1 +O=C(CC1C=CCC1)NCCc1coc(-c2ccc(F)cc2)n1 +Cc1nc(-c2ccc(NC(=O)C3CC(=O)N(C(C)C)C3)cc2)oc1C +Cc1csc(NC(=O)Cc2ccc3c(c2)CCO3)n1 +Cc1nnn2c1COCC(CNC(=O)c1ccc[nH]1)C2 +Cc1nc(C2CCCN2C(=O)C2CC=CCC2)no1 +Cc1ccc2c(c1)c1c(n2C)C(C)(C(N)=O)CCC1 +N#CCCN(CC1CC1)C(=O)c1c[nH]c2cccc(F)c12 +O=c1[nH]ncc(NCCOc2ccc(Br)cc2)c1Cl +O=C(Nc1ccc(F)cc1)c1ccc(N2CCCOC2=O)cc1 +CCC(CO)NC(=O)Nc1ccccc1S(=O)(=O)C(C)C +COc1ccccc1-c1nnc(C2CCN(Cc3ccccc3C)C2)o1 +CCC(C)(C)NC(=O)c1ccc(Cl)c(S(=O)(=O)NC2CC2)c1 +Cc1ccccc1OCCNC(=O)N(C)CC1CCCO1 +CCC(C)NC(=O)c1cnc(CCc2ccccc2)nc1N +COC(=O)CN(Cc1cnn(C)c1)S(=O)(=O)c1cccc(C)c1 +O=C(Nc1ccc(OCc2ccccc2)cc1)N1CCC(CO)CC1 +Cc1ccc(CC(=O)Nc2ccccc2Cn2cccn2)s1 +CCOC(=O)c1csc(CNC(=O)c2cccc(OC)c2F)n1 +Cc1ccc(CNC(=O)C(C)Sc2nnc(C)c(=O)n2N)cc1 +COc1ccc(S(=O)(=O)NCc2ccccc2)cc1-n1cnnn1 +CC(=O)N(C)CC(=O)Oc1ccc(C2CCCCC2)cc1 +CCC(C)n1nccc1NC(=O)c1cccc(OC(F)F)c1 +Cc1nc2ccccn2c(=O)c1NC(=O)c1ccc(C(F)(F)F)cc1 +COC(=O)CCCn1cnc2cc3c(cc21)OCCO3 +NC(=O)CCN(C(=O)c1cn(Cc2ccccc2)nn1)c1ccccc1 +COc1ccccc1CCNS(=O)(=O)c1ccc(C)cc1 +COc1cc(C(C)C)ccc1-c1c[nH]c(N)c1C#N +COC(C)(C)CC(C)NC(=O)C1COc2ccc(F)cc2C1 +COc1ccc(Cl)cc1NC(=O)NCc1cccnc1 +CCCOc1cccc(NCc2noc(C3CC3)n2)c1 +COc1ccc(C)cc1NC(=O)CSc1nc(C)cc(C)c1C#N +CC(C)NC(=O)CSc1nnc(-c2cccs2)n1CC(N)=O +CC1=C(N)c2ccc(Oc3ccccc3)cc2S1=O +CC1CN(C(=O)c2n[nH]c(C(C)C)c2N)CCCO1 +CN(C)C(=O)Cc1ccc(NC(=O)NCc2ccccc2)cc1 +O=C1CCc2cc(S(=O)(=O)NC3CCC(O)CC3)ccc2N1 +NC(=O)COc1ccc(NC(=O)NCc2cccs2)cc1 +Cc1ccc(OCCNC(=O)C(C)NC(=O)Nc2ccccc2)cc1 +O=C(NCc1c(F)cccc1Cl)c1cnc(-c2cccnc2)nc1 +O=C(CC1CCCO1)NCCN1CCCS1(=O)=O +Fc1cccc(-c2ncncc2Br)c1F +C=CCNc1ccccc1C(=O)NCc1nc(C)c2c(n1)CCCC2 +Cn1ccc(C(=O)Nc2nnc(-c3cccs3)o2)n1 +CC(=O)Nc1nc(C(=O)NCc2nnc3n2CCC3)cs1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(N)nc1 +Cc1cc(C)n(CC2(CNC(=O)c3cc(CC(C)C)nn3C)CC2)n1 +CN(CC(F)(F)F)C(=O)CN1CCN(c2ccccc2)CC1 +COc1cc(C)ccc1OCC(=O)N1CC(C)c2ccccc21 +Cc1nn2cccnc2c1C(=O)NC(C)Cc1ccc(F)cc1 +COCc1cc(C(=O)Nc2cccc(-c3nnnn3C)c2)ccc1F +Cc1cccc(C(C(=O)NCc2ccnc3ccccc23)N(C)C)c1 +Cn1c(CCCNC(=O)c2scnc2C2CC2)nc2ccccc21 +CCCCCCOc1ccc(C(=O)N2CCOCC2)cc1 +Cc1cc(NC(=O)C2CCN(S(C)(=O)=O)CC2)n(CCO)n1 +CCCCN1CC(C(=O)N2CCCCC2CC)CC1=O +CCC(=O)N(Cc1cccnc1)Cc1cc2cccc(C)c2[nH]c1=O +NC(=O)c1cccc(C(=O)NC2CCN(C(=O)c3ccoc3)CC2)c1 +C=CCn1c(SC(C)C(=O)OC)nc2c(oc3ccccc32)c1=O +CC(=O)c1cccc(NC(=O)c2cn(C)nc2C(F)(F)F)c1 +O=C1CCN(S(=O)(=O)c2ccc(F)cc2F)CC1 +CC1CCc2cccc(NS(=O)(=O)C(C)C)c2N1 +O=S(=O)(NCCc1nc2ccccc2[nH]1)c1ccccc1 +CC(=O)NC(C(=O)Nc1ccc(N2CCOCC2)cn1)C(C)C +Cc1cccc(C(=O)Nc2ccccc2-c2nc3ccccc3[nH]2)n1 +C=CCOc1ccc(C(=O)NCc2cccs2)cc1 +CCOC(=O)c1c(NC(=O)c2cc(C)n(C)n2)sc2c1CCC2 +Cc1ccn(CCC(=O)Nc2ccc(F)cc2Cl)n1 +Cc1nc(C(=O)NCC#Cc2cccc(C(F)(F)F)c2)cs1 +CN(C)C(=O)CCNC(=O)NC1CCN(c2ccccc2)C1 +O=C(NCc1nc2ccccc2[nH]1)c1ccc(NC(=O)C2CC2)cc1 +CC(=O)c1c(C)[nH]c(-c2csc(C3CC3)n2)c1C +Cc1ccc(-c2cc(C)nc(-n3nc(C)cc3N)n2)cc1 +O=C(C1CC=CC1)N1CC2CCN(CC3CC3)C(=O)C2C1 +CC(C)(C)n1c(C(F)(F)F)nc2cc(N)ccc21 +CC(Oc1ccccc1)C(=O)Nc1cc(-c2ccco2)no1 +Cc1ccc(CNC(=O)CN(C)S(=O)(=O)c2ccccc2)c(C)c1 +CCNC(=O)CN(C)C(=O)c1ccc(N(C)CC)cc1 +CCCCc1n[nH]c(SCC(=O)NC2Nc3ccccc3S2)n1 +OCc1nc2ccccc2n1CC1(O)CCCCC1 +Cc1cccc(OCc2ncc(C(=O)NC(C)C)c(N)n2)c1 +Cc1nc(C2COCCN2Cc2ccc3c(c2)OCO3)cs1 +COC(=O)c1cccc2[nH]c(=NC(=O)C3CCC(F)(F)CC3)[nH]c12 +CCCCc1ccc(NC(=O)CS(=O)(=O)c2ccccc2)cc1 +CC(=O)NCC1CCN(c2c(F)cc(C#N)cc2F)CC1 +CCCCn1nccc1NC(=O)c1ccc(SCC)nc1 +COc1ccccc1-c1csc(NC(=O)CCc2ccncc2)n1 +O=C(Nc1cnccc1CO)c1cccc(Cl)c1F +Cc1ccc(N2CC(C(=O)OCC(N)=O)CC2=O)c(F)c1 +O=C(CCSc1ccccn1)NC1CCc2cc(F)ccc21 +Cc1ccc(CNC(=O)c2cc(C)on2)c(OCC2CCOC2)c1 +COc1cc(C(=O)N(C)CCc2ccc(F)cc2)cc(OC)c1OC +CC(C)(NC(=O)c1ccc(-n2cccn2)cc1)c1ccc2c(c1)OCO2 +CN(C(=O)CSc1ccccn1)c1ccccc1 +Cn1c(=O)oc2cc(NS(=O)(=O)c3cccc(Cl)c3)ccc21 +CC(=O)Nc1ccc(F)c(C(=O)NCC(C)(C)c2ccncc2)c1 +Cc1ccc(S(=O)(=O)Oc2cc(Cl)ccc2C(N)=O)cc1F +Cc1ccc2ncc(C(=O)N(Cc3ccncc3)C3CC3)n2c1 +COCCn1nc(C(=O)NCc2ccoc2)ccc1=O +CCC(CC)CN(CC)C(=O)c1cc(Br)cnc1N +O=C(Nc1cc(N2CCCS2(=O)=O)ccc1F)C1CCOCC1 +Cc1cc(C)c(C(=O)NC2CCCn3nc(C)nc32)c(C)c1 +CCOC(=O)C1CCN(C(=O)CSc2nncn2C)CC1 +CCOc1ccc(S(=O)(=O)N2CCN(C3CC3)CC2)cc1 +CSc1nc(C)c(CCC(=O)Nc2cccc(C)n2)c(=O)[nH]1 +COCCn1ccc2cc(NC(=O)N3CCOC(C)C3)ccc21 +Cc1noc(C)c1C(C)C(=O)N1CCCC(c2noc(C(C)C)n2)C1 +CCN(CC(=O)NC(C)C)C(=O)COc1cccc(Cl)c1 +CC(C)c1nn2c(CO)c(-c3cccs3)nc2s1 +CC(C)c1cc(C(=O)N(CCO)Cc2ccccc2)c2ccccc2n1 +Fc1cc(Cl)cc2c1C(Cn1cnnn1)NCC2 +Cc1n[nH]c(CCC(=O)N(Cc2ccccc2Cl)C(C)C)n1 +O=C(c1ccc(O)c(Cl)c1)N(Cc1ccsc1)C1CC1 +C=CCN(Cc1cccs1)C(=O)CSc1nc(C)cs1 +O=C(CN1CCOc2ccc(Cl)cc21)NC1CCC(O)CC1 +CCc1ccc(-c2ccc(=O)n(CC(=O)NCC3CCCO3)n2)cc1 +COc1cc(C)sc1C(=O)Nc1cc(-c2cccs2)n[nH]1 +CC(C)c1cc(C(=O)Nc2cc(Cl)ccc2O)no1 +CN(Cc1ccccc1)C(=O)CC(C#N)c1cccs1 +COc1cccc(SCC(=O)c2cc(C)n(C3CC3)c2C)c1 +O=C(c1ccccn1)N1CCCC2(CC(Oc3cccnc3)CO2)C1 +Nc1cc(Cl)ccc1NS(=O)(=O)Cc1ccccc1 +Cc1n[nH]c2c1C(c1ccc(OCc3ccccc3)cc1)CC(=O)N2 +O=C(Cc1csc(-c2nc[nH]n2)n1)NCCNC(=O)C1CCCC1 +CCC(=O)Nc1cc(S(=O)(=O)NCC(C)C)ccc1OC +CN1CCc2cc(C(=O)Nc3cccc(F)c3)ccc21 +CCCn1c(-c2cccc(C)c2)nnc1S(=O)(=O)Cc1ccon1 +O=C(Cc1ccc(F)c(F)c1)Nc1ccc(Br)cn1 +CC1(C)OCC2(CO1)CN(C(=O)Cn1c(=O)oc3ccccc31)C2 +Cc1ncc(C(C)NCCc2cc(F)cc3c2OCOC3)s1 +CCN(CC)C(=O)c1ccccc1NCC(=O)N(C)C1CC1 +Cc1occc1CN(C)C(=O)C1CCCCN1C(=O)c1ccco1 +CSc1nc(=O)n(-c2ccccc2)c(C)c1C(C)=O +Cc1ccc2c(=O)cc(C(=O)NCc3cnn(C)c3)oc2c1C +CN1C(=O)Cc2cc(NC(=O)c3cccc(Cl)c3)ccc21 +CCNc1ncccc1COc1cccc(CO)c1 +CCn1nc(C)cc1C(=O)NCC(=O)NCCc1cccc(F)c1 +c1coc(CN2CC3c4ccccc4C(N4CCOCC4)C3C2)c1 +O=S(=O)(NCC#CCOc1cccnc1)C1CC1 +CN(C)c1ccc(C(=O)N(CCC#N)Cc2cccnc2)cn1 +CCC(C)NC(=O)C(C)Sc1nc(C)cc(C)c1C#N +Cc1cc(OCC(=O)Nc2ccccc2OC(F)F)no1 +CC(C)Oc1ccc(CSc2nncn2N)cc1 +COc1c(C)cnc(CN(C)C(=O)CCC(C)C)c1C +Cc1ccc(NC(=O)CN(C)C(=O)c2cccc(C)c2)cc1 +CC(Oc1ccc(F)cc1F)C(=O)N1CCOCC1 +N#CCOc1ccc(NC(=O)c2ccc(-n3cccc3)cc2)cc1 +C=C(C)CN(c1ccc(C(=O)OC)cc1)S(C)(=O)=O +CC1CCN(C(=O)Cc2cc(-c3ccc(F)cc3)on2)CC1 +Cc1cccc2nc(CSc3ccccc3)cc(=O)n12 +FC(F)(F)c1ccnc(N2CCCN(c3ncccn3)CC2)n1 +CCN(CC)C(=O)C1CCCN1C(=O)CNC(=O)NC +CC(Cn1cccn1)NC(=O)C1Oc2ccccc2OC1C +CN(C)c1ncccc1N(C)C(=O)C1CCOc2ccc(Cl)cc21 +COc1ccccc1CNC(=O)c1ccc(NC(=O)C(C)C)cc1 +COc1ccc(C(=O)NCCCC(=O)NC(C)(C)C)cc1 +COc1ccc(C(=O)CCC(=O)N(C)Cc2ccc(C)s2)cc1 +C=CCNC(=O)C(C)Oc1ccc(Cl)c(C)c1 +COc1cc(NS(=O)(=O)c2ccccc2F)ccc1NC(C)=O +Cc1noc(CCC(=O)OCCn2cccn2)n1 +CNC(=O)c1cc(NC(=O)N(C)CCC#N)ccc1F +CCOCCCNC(=O)Cn1nc(C)c2ccccc2c1=O +Cc1ccc(C)c(S(=O)(=O)CC(=O)N2C(C)CCCC2C)c1 +N#CCCC(C#N)CSc1nc(-c2ccccc2F)n[nH]1 +CC(C)(C)N1CC(C(=O)NCCn2cccc2)CC1=O +CC(C)c1ccc(C(=O)NC2CCCNC2=O)cc1 +C=C(C)CSc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 +Cc1c(N)cccc1NC(=O)COc1ccccc1 +CC1=CC(C)=NC(=O)C1CNC(=O)c1ccc(N2CCCC2=O)cc1 +CC(=O)NCC(=O)NC(C)c1ccc(Cl)cc1Cl +Cc1cccc(NC(=O)c2cc(-c3ccco3)nc3onc(C)c23)c1 +O=C(OCCc1cccs1)c1ccc(-n2ccnn2)cc1 +COc1c(Cl)cccc1NC(=O)NCC(=O)NC(C)C +O=C(c1cc(F)ccc1Cl)N1CCN(c2ccccc2F)CC1 +O=C1CCC2(CCOC2)CN1CCN1CCN(c2ncccn2)CC1 +Cc1ccc(C(O)(CCNC(=O)Nc2ccccn2)C(F)(F)F)o1 +O=C(Nc1cccc(-c2nccs2)c1)c1cn[nH]c1 +Cc1cnc2n(c1=O)CC(C(=O)NCc1cccnc1)CS2 +CS(=O)(=O)c1ccc(N2CCC3(CC2)OCCO3)c(F)c1 +Nn1c(SCC(=O)NC2CCCCC2)nnc1-c1cccc(F)c1 +CCn1cnnc1CNC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +Cc1ccc(C(=O)NCc2csc(-c3ccccc3)n2)o1 +COc1cc2ncnc(SCc3ccco3)c2cc1OC +COc1ccc(NC(=O)N2CCCC2c2cc(C)on2)cc1OC +CN(C)C(=O)CN(c1cccc(F)c1)S(C)(=O)=O +COCCc1noc(CNC(=O)C2COc3ccccc3C2)n1 +Nc1nc(N)c(S(=O)(=O)c2ccccc2)c(NC2CCCCC2)n1 +Nc1c(F)cccc1C(=O)NCc1ccccc1Cl +Cc1noc(CC2COCC3CN(C(=O)c4ccccn4)CC23)n1 +Fc1ccccc1CSc1nnnn1-c1cccnc1 +Cc1nn(C(C)C)c(C)c1NC(=O)Nc1ccc(-n2cncn2)nc1 +COC(=O)C(C)Sc1nnc(Cc2cccs2)n1C1CC1 +CC(C)(C)CC1NCCc2c(Cl)cc(F)cc21 +Cn1cnc(S(=O)(=O)N2CCC(c3ccncn3)CC2)c1 +CCC(=O)c1ccc(OCc2nnc(-c3ccc(OC)cc3)o2)cc1 +Cc1noc(C)c1C(=O)NCCCCCc1nnc2ccccn12 +CCc1noc(CN(C)Cc2ccc(-c3ccncc3)cc2F)n1 +CCCCCCNC(=O)C1CCN(C(=O)c2ccoc2)CC1 +CC(=O)c1ccc(OCC(O)Cn2nnnc2-c2ccccn2)cc1 +O=c1[nH]c(-c2ccc(Cl)cc2)nn1-c1ccccc1 +COc1ccc(C(O)C(C)NC(=O)Nc2c(C)ccn(C)c2=O)cc1 +CN(C)c1cccc(C(=O)Nc2cc(-c3ccsc3)no2)c1 +CC(C)N1CCCC2(CCCN2C(=O)OC(C)(C)C)C1=O +CCN(CCC#N)C(=O)CNc1cc(F)cc(Br)c1 +CCCCC1(C)Nc2cc(F)ccc2N(CCCC#N)C1=O +Cc1cnn(C2CCCN(C(=O)c3cnc4[nH]nc(C)c4c3)C2)c1 +CN(C)C(=O)CN(C)c1c(C#N)c(=O)n(C)c(=O)n1C +O=C(CN1CCOCC1)Nc1ncc(Cc2ccc(F)cc2)s1 +CC1CCN(CC(=O)Nc2ccccc2C(N)=O)c2ccccc21 +CCc1nc(CN2CCN(Cc3sccc3C)CC2)cs1 +CN(Cc1cnn(C)c1)C(=O)Cc1cc(Cl)c2c(c1)OCCCO2 +COc1ccc(CCCC(=O)N2CC(C)(C)C(C)(O)C2)cc1 +COC(=O)C1(NC(=O)c2[nH]nc(C)c2Br)CCCCC1 +COCCOc1ccccc1NC(=O)c1scnc1C +CC1CN(CC(=O)Nc2ccc(F)c(Cl)c2)c2cc(N)ccc2O1 +CCCc1cc(C(=O)Nc2n[nH]c(-c3ccco3)n2)sc1C +CC(c1ccccc1Cl)N1CCN(C(=O)Nc2ccncc2)CC1 +O=C(Nc1ccc(OCC2CCCO2)cc1)C1CCCC1 +COc1cc2[nH]c(C)c(CC#N)c(=O)c2cc1OC +Cc1cccc(-c2nnc(C)c(N3CCOCC3)n2)c1 +CCc1ccc(-c2ccc(=O)n(CC(=O)Nc3nccs3)n2)cc1 +CC(C)CN1C(=O)C2(CC2C(=O)NCc2cccnc2)c2ccccc21 +CCC(C)NC(=O)c1ccc(NC(=O)C(C)NC(C)=O)cc1 +Cc1ccc(OC(C)C(=O)N(C(C)C)C2CCOCC2)cc1 +CC(C)CCNS(=O)(=O)c1cnn(C2CCCC2)c1N +Cc1ccn2c(=NC(=O)c3cccc(Br)c3)[nH]nc2c1 +O=C(NC1C2CC3CC(C2)CC1C3)c1ccnn1C(F)F +CCN(CC(C)C#N)S(=O)(=O)c1ccc(F)cc1Br +O=C(C1CCC1)N1CCN(Cc2ccsc2)CC1 +Cn1c(NCCO)nc2c1c(=O)n(CC(N)=O)c(=O)n2C +Nc1ccc2c(c1)nc(-c1ccccc1)n2-c1ccncc1 +CN1CCN(c2nc(C3CC3)no2)Cc2ccccc21 +Cn1ccc(Cn2nnn(-c3cccs3)c2=O)cc1=O +O=C(CCNc1ncccn1)Nc1ccc(Cl)cc1Cl +Cc1ccc(C(=O)Nc2cccc(Cn3ccnc3)c2)s1 +CCC(CO)NC(=O)NC(C)c1cccc(N2CCCC2=O)c1 +CC(C)NC(=O)Cc1cc(-c2ccc(F)cc2F)on1 +CN(Cc1cc(C(N)=O)cs1)C1c2ccccc2-c2ccccc21 +CC(C)n1nc2c(S(=O)(=O)N3CCOCC3)cccn2c1=O +CCc1nnnn1-c1ccccc1NC(=O)C1CC1 +CC(NC(=O)c1ccc(S(C)(=O)=O)cc1)c1cc2ccccc2o1 +CC(=O)c1ccccc1OC(C)C(=O)Nc1ccccc1C +CC(C)(C)CNC(=O)c1[nH]cnc1C(=O)NCC1CC1 +CN(C)C(=O)N1CCCC(C(=O)Nc2ccccc2F)C1 +COc1cc(Br)c(OC)c(C(N)=O)c1 +O=C(NCCCN1CCOCC1)Oc1ccccc1 +CCNC(=O)C1CCN(CC(=O)c2cc(C)n(CC)c2C)CC1 +CN(C)c1ccccc1C#CCNC(=O)c1cnn(-c2ccccc2)n1 +Cc1nn(C)c(C)c1S(=O)(=O)NCc1ccc(-n2cccn2)cc1 +Cc1c(F)cccc1NCc1noc(-c2cccs2)n1 +CS(=O)(=O)c1cccc(C(=O)Nc2ccc3ncsc3c2)c1 +COc1ccc(NC(=O)COC(C)CC(C)C)c(N)c1 +Cc1ccc2nc(C)c(NC(=O)C3CCCC3)c(=O)n2c1 +C=CCN(CC=C)C(=O)CCn1ccc2ccccc21 +Cc1ccc2c(Nc3nnc(C(C)C)s3)cc(C)nc2n1 +Cc1noc(C(C)C)c1C(=O)NCc1nccs1 +CC(C)(C)OC(=O)N1CCC(NC(=O)CCNC(=O)C(C)(C)C)C1 +CC(C)c1nc(C2CCN(C(=O)c3ccsc3)CC2)no1 +Cn1cnnc1CNC(=O)c1cccc(F)c1F +Cc1c(C(=O)N(Cc2ccccc2)CC2CCC2)cnn1C +COCCN(CCC#N)Cc1cc2cc(C)c(C)cc2o1 +O=C(NCc1ccc(Br)cc1)c1cccs1 +COCCOc1ncccc1C(=O)Nc1ccccc1O +O=C(Nc1cccc(NS(=O)(=O)c2ccccc2)c1)c1ccon1 +CCN(CCO)S(=O)(=O)c1cccc(Cl)c1Cl +CC1(N2CCCCC2)COc2ccc(Br)cc2C1=O +O=c1[nH]c(Nc2c(F)cccc2F)nc2c1CCC2 +Cn1ccc(NC(=O)NCCCOCC2CCOCC2)n1 +CNC(=O)c1ccc(C)c(NC(=O)c2nn(-c3ccccc3)nc2C)c1 +CNS(=O)(=O)c1ccc(CNC(=O)N(C)C(C)C)cc1 +O=C(C1CCCCC1)N1CCC(CN2CCOCC2)CC1 +Cc1ccncc1NCc1cccc(F)c1Cl +CC(=O)N1CCc2ccc(NC(=O)CSc3ccc(F)cc3)cc21 +O=C(NCc1cccc2ccccc12)C1CC(=O)N(Cc2ccco2)C1 +CCCOc1cc(CO)cc2c1OC(CC)C(=O)N2 +COC(=O)CSc1nc2ncc(C(C)=O)c(C=CN(C)C)n2n1 +Cc1csc(C2CCCCN2C(=O)CCn2ccnc2)n1 +O=C(Nc1nnc(C23CC4CC(CC(C4)C2)C3)s1)c1ccncc1 +Cc1cc(-c2nnc(SCC(=O)Nc3ccccc3)o2)no1 +Cc1nc2ccc(NC(=O)c3c(C)oc4nc[nH]c(=O)c34)cc2s1 +COCCNC(=O)COc1coc(CO)cc1=O +Cc1cccc2nc(CSc3ncn[nH]3)cc(=O)n12 +COc1ccccc1C(O)c1cccnc1-n1nnc2ccccc21 +Cc1cc(C)c(CNC(=O)c2cc(C3CC3)nc3ccccc23)c(=O)[nH]1 +COc1cc(N)cnc1Oc1ccc(Cl)cc1C +CNC(=O)NCC(=O)N1CCOC(c2ccccc2Cl)C1 +COc1cccc(OC)c1C(=O)Nn1c(C)nc2ccccc2c1=O +O=C1c2ccccc2-c2c1cccc2C(=O)N1CCCCC1 +O=C(CCn1ncc(=O)c2ccccc21)NCC1Cc2ccccc2O1 +COc1ccc(C(=O)c2ccc(O)cc2)cc1OC +COc1cccc(S(=O)C2CCCN(C(=O)OC(C)(C)C)C2)c1 +C(=Cc1nc(COc2ccccc2)no1)c1ccc(-n2ccnc2)cc1 +CN(C(=O)c1cn(-c2ccccc2)nn1)c1ccc(F)c(F)c1 +O=C(CCNC(=O)c1ccco1)NCc1cccnc1 +O=c1[nH]c(CSc2ccc(O)cc2)nc2ccc(Cl)cc12 +NC(=O)Cc1csc(NC(=O)CCC2CCCO2)n1 +COc1ccc(F)cc1NC(=O)N(C)CC1CCOC1 +Cc1n[nH]cc1CNC(=O)c1cc(-c2ccccc2)on1 +O=C(NCc1cn[nH]c1)c1cncn1-c1ccccc1 +COC(=O)COc1ccc2cc(C(C)=O)c(=O)oc2c1 +CS(=O)(=O)NCCn1nnc(-c2cccc(C(F)(F)F)c2)n1 +O=C(CCn1ccc2ccccc21)NCC(O)c1ccccc1Cl +Cc1ccoc1C(=O)NCCSc1ccc(Cl)cc1 +Cc1ccc(S(=O)(=O)N2CC3CC2CO3)cc1 +Cc1cn2c(=O)c(C(=O)Nc3nccs3)cnc2s1 +Cc1ccc(OCC(=O)Nc2ccc(N3CCOCC3)cn2)cc1C +CCOc1ccc(CNc2cc(Cl)ccn2)cc1 +COc1cccc2c1C(c1ccc[nH]c1=O)NCC2 +Cc1nc(SCC(=O)NC(C)c2ccccc2)c2ccccc2n1 +Cc1nc(C(=O)NCC(O)Cc2ccccc2)cs1 +COc1ccccc1CC(=O)NCCNC(=O)c1ccc(F)cc1 +Cc1ncc(CNC(=O)c2sccc2Br)s1 +COc1ccc(-c2noc(-c3cnc(C)[nH]c3=O)n2)cc1 +COC(=O)C1CCCN1C(=O)c1nccc2c(F)ccc(N)c12 +CC(NC(=O)Cc1ccc(C(F)(F)F)cc1)C(=O)N1CCOCC1 +COc1ccnc(NC(=O)c2cc(C)n(Cc3ccccn3)c2C)c1 +COC1C2CCC1CN(c1nc(C)nc3ccsc13)C2 +CCN(CC)c1c(C#N)c(=O)oc2c(OC)c(OC)ccc12 +COCC1CN(C(=O)c2cnccn2)Cc2ccnn2C1 +COc1ccc(F)c(NC(=O)Cc2ccc(C)nc2)c1 +CC(C)CN1CC(C(=O)Nc2cnc3c(cnn3C(C)C)c2)CC1=O +NC(=O)c1ccc(-n2nnc(CO)c2-c2cccnc2)cc1 +CC(C)OCc1c(C(=O)NCc2cccc(C#N)c2)oc2ccccc12 +Fc1ccc(F)c(CN2CC(c3nc(-c4cccs4)no3)C2)c1 +Cn1c(=O)c2cc(C(=O)N3CCNC(=O)C3)cnc2n(C)c1=O +O=C(CN1CCN(c2ccccc2F)CC1)N1CCOCC1 +Cc1noc(C2CCCN2C(=O)Nc2ccccc2C(F)(F)F)n1 +Cn1cc(CN2CC3CC(C(=O)NCc4cccnc4)C(C2)O3)cn1 +COCC(C)NC(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1C +CCCc1cc(=O)[nH]c(SCC(=O)Nc2c(C)cccc2C)n1 +O=C(NCCCO)Nc1ccccc1OCC1CCCCO1 +CCCCCNc1nc(C2CCCO2)nc(OC)c1N +CC(=O)NCCC(=O)N1CCN(CC(C)(C)O)CC1 +CN(CC(=O)Nc1cccc(Cl)c1)S(=O)(=O)c1cnn(C)c1 +CCn1ccc(C(=O)N(C)CC(=O)N2CCC(CCOC)CC2)n1 +CCCNc1ncnc(NCc2ccc(Cl)cc2)c1N +Cn1cc(C(=O)NCc2ccccc2C(F)(F)F)c(=O)c2cccn21 +O=S(=O)(CCSc1nc(-c2cccnc2)n[nH]1)c1ccccc1 +CC(=O)N(C)CC(=O)Nc1c(C)nn(-c2ccccc2)c1C +Cc1cccc(OCC(=O)N2CCCC2c2nnc3ccccn23)c1 +CCCCNC(=O)c1cc2c([nH]c1=O)CC(C)(C)CC2=O +CCNc1ncnc(N(CCC#N)CCC#N)c1N +O=C(OCC(F)(F)C(F)F)c1ncn(-c2ccccc2)n1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1cccnc1OCC(F)F +Cc1ccc(NC(=O)NCCCn2cnc3ccccc32)cc1F +CCn1ncc(S(=O)(=O)NC2CCCCCC2)c1N +N#CC1(C(=O)NCc2ccccc2COCc2ccccc2)CCC1 +Cc1c[nH]c(=O)n1-c1ccc(C(=O)OCC(=O)NC(C)C2CC2)cc1 +CSc1ccc(Cl)cc1NC(=O)Cc1c(C)noc1C +Cc1ccccc1C(=O)NCc1cnn(Cc2ccccc2)c1 +CC(=O)NC(CC(=O)Nc1ccc(C(C)C)cc1)c1ccccc1 +O=C(COc1cccc(-c2nnco2)c1)Nc1cccc(F)c1 +CCOC(=O)C(O)(c1cc(C)c(Cl)cc1O)C(F)(F)F +CCOc1ccc(C(=O)CSc2nc(C)cc(N)n2)cc1 +CC(C)NC(=O)c1ccc(NC(C)C2(C)CC2)cc1 +COCCn1cnnc1SC(C)c1ccc(F)cc1F +Cn1cc(C(N)=O)cc1C(=O)OCc1nccn1CC(F)(F)F +CCCC1CN(C(=O)CCCc2ccc3c(c2)CC(=O)N3)CCO1 +CS(=O)(=O)c1ccccc1C(=O)OCC(=O)Nc1ccccc1O +CCC(CC)C(=O)NC1CC(=O)N(c2ccccc2)C1 +CC1(C)c2ccc(Cl)c(N)c2CN(C2CC2)S1(=O)=O +c1nc(N2CC3C4CCC(O4)C3C2)c2nc[nH]c2n1 +Cc1nc(C(=O)N2CC(C)OC(C)C2)nn1-c1ccccc1C(C)C +Cc1cc(C)c(OCCn2c(=O)oc3ccc(N)cc32)c(C)c1 +CC(C)n1cnnc1SCC(=O)NCCc1ccccn1 +COC(=O)c1ccc(C=Cc2nc(-c3ccc(C#N)cn3)no2)cc1 +CC(O)(CCc1ccccc1)CNC(=O)C1CCC1 +CC(=O)NCC(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1C +COc1ccc(N)cc1OCc1cc(C(N)=O)ccc1F +COc1ccc(O)c(C(=O)NCCC(=O)N2CCCCC2)c1 +CC(Cc1ccccc1F)NC(=O)C1(C#N)CCCC1 +COc1ccc(S(=O)(=O)N2CCC(c3ccncc3)CC2)cc1 +CCc1nc(COc2cccc(C)c2)sc1CO +Cc1cc(C)n(C(C)CNC(=O)c2ccc3c(c2)ncn3CCO)n1 +Cc1cc(=O)n(CC(=O)N2CCCc3ccccc32)cn1 +Cc1ccc(CN2CCN(C(C)c3cccnc3)CC2)s1 +CC(=O)Nc1ccc(-c2nc3c(Cl)cccn3c2N)cc1 +COc1ccc(C(NC(=O)C2COc3ccccc3O2)C(C)C)cc1 +Cc1cccc(Oc2ccc(NC(=O)c3ccc(=O)n(C)n3)cc2)c1 +COc1cccc(C(=O)NCc2cn3ccc(C)cc3n2)c1 +COc1cc(OC)c(NC(=O)N2CCOCC2C2CC2)cc1F +Cc1ccc(OCC(C)NC(=O)NCC2CC2)cc1 +CN(Cc1cnn(Cc2ccccc2)c1)c1ncnc2ccccc12 +CC(NC(=O)c1ccoc1)C(=O)N(Cc1ccco1)C1CCCC1 +CN(Cc1ccccc1Cl)C(=O)CNC(=O)c1cccc(F)c1 +Nc1nc2c(cc1C(=O)Nc1ccccc1)CCC2 +CCOC(=O)Cc1nc(CNc2cccc(C)c2)n[nH]1 +C#CCN1CCN(C(=O)NCCc2ccc(O)c(OC)c2)CC1 +Cc1c(CC(=O)N2CCCCC2)c(=O)oc2cc(O)c(Cl)cc12 +CCN(Cc1ccccc1)C(=O)c1cnc(C2CCCO2)s1 +CCCn1cnnc1C(C)NC(=O)c1ccncc1Cl +CCc1ccc(CNC(=O)c2csc(C)n2)s1 +CC#Cc1cn(C2OC(CO)C(O)C2O)c(=O)nc1N +CC(C)c1csc(C2CCCN(C3CCOC3=O)C2)n1 +Cc1cccc(C(=O)OC(C)c2ccc(Cl)cc2)n1 +CCN(CC(=O)c1[nH]c(C)c(C(=O)OC)c1C)c1ccccc1 +CCn1c(SCC(=O)c2ccc(C)cc2)nnc1C1CC1 +CCN(CC)C(=O)N1CCCC(C(=O)NCCc2ccccc2)C1 +Cc1cc(NC(=O)C(Cc2cccc(F)c2)n2nnnc2C)n(C)n1 +C=C(C)CN(CC)c1nc2sccn2c1CO +COc1ccc(C(=O)NCCc2csc(-c3ccccn3)n2)cc1 +CCOC(CC)C(=O)N1CCC2(CC1)OCCO2 +CCOC(=O)c1c[nH]c2cc(F)c(OC)cc2c1=O +CC(C)CCNC(=O)C(C)S(=O)(=O)c1nnc(N(C)C)s1 +Cc1ccc(-c2nnc(-c3cccc(N)c3)o2)s1 +CCN(c1cccc(CO)c1)S(=O)(=O)c1cccc(C)c1 +CCn1cnnc1CNC(=O)c1cc(OC)c2c(c1)OCCO2 +C=C(C)C1NCCc2cc(O)c(OC(F)F)cc21 +COCC1CCCN(C(=O)Nc2cccc(Cl)c2)C1 +O=C(COc1ccccc1F)N1CCC(Cn2cccn2)CC1 +Cc1cc(NC(=O)N2CCCC2c2cccnc2)no1 +N#Cc1ccc(-c2cccs2)n2nc(CCN3CCOCC3)nc12 +Cc1cc(C(=O)N2CCN(c3nccs3)CC2)c(C)o1 +Cc1cc(C)n(-c2ncnc(NC(C)c3ccccc3)c2N)n1 +CSc1ccc(C)c(C(=O)NCCCC(N)=O)c1 +CSc1cccc(NC(=O)CCC(=O)c2cc(C)sc2C)c1 +Cc1cccc(N2CCN(C(=O)c3cn4cc(C)ccc4n3)CC2)c1 +Cc1ccc(C(=O)NCCOc2ccccc2-c2ccccc2)c(=O)[nH]1 +CC(C)CCNC(=O)c1nnc(C(=O)Nc2ccccc2)s1 +CC(C)NC(=O)c1ccc(NCC2CCOC2)cc1 +CCS(=O)(=O)c1cccc(NC(=O)CCC(C)(C)C)c1 +CC(C)(C)OC(=O)N1C2CCC1CC(NC(=O)CC1C=CCC1)C2 +CC(CO)(NC(=O)Nc1cccc(C(=O)N2CCCCC2)c1)C1CC1 +O=C(Cc1ccc(F)c(Br)c1)NCC1CCOC1 +CC(C)CC(C)OCCC(=O)NC1CCN(C(N)=O)CC1 +COc1cccc(CC(=O)N2CCC(OC)C3OCCC32)c1 +Cc1cccc2c(=O)n(CCC(=O)N3CCNC(=O)C3)cnc12 +CCNC(=O)NC1(C(=O)NCCOc2ccc(C)cc2)CCCC1 +Cc1ccc(CN(C)C(=O)c2ccc(=O)[nH]c2)c(C)c1 +CC(NCC(O)c1ccco1)c1ccc(C#N)s1 +Nc1c(-c2ccc(F)cc2)nsc1C(=O)NCc1cccs1 +CCC(CC)(CO)NC(=O)Nc1ccc(OC)cc1 +CCC(C)C(NC(=O)c1csc2c1CCCC2)C(N)=O +CC(=O)Oc1ccccc1NC(=O)CCc1ccccc1 +CN(Cc1cc(Br)cs1)C(=O)C1CCC1 +Cc1ccc(OCC(=O)N2CCCC2C(=O)NCc2ccco2)cc1 +Cc1nn(C)c2sc(-c3nc(C4CC4)no3)cc12 +COc1ccc(CC(=O)N2CCC(c3nc4ccccc4[nH]3)CC2)cc1 +O=c1oc2cc(OCC(O)CN3CCOCC3)ccc2c2c1CCC2 +COc1cc2c(cc1OC)C1C(O)C(OC)C=C3CCN(C2)C31 +CCC(C#N)Oc1cccc(CNC(=O)c2ccc(C(C)=O)cc2)c1 +CSc1ccc(OCCn2nc(C)ccc2=O)cc1 +Nc1ccc2c(c1)CC(=O)N2CCOc1cccc(Cl)c1 +CCS(=O)(=O)N1CCCC(CCc2cccc(F)c2)C1 +CCc1nnc2n1CCN(c1nccc(OC)n1)C2 +CC(=O)Nc1ccc(N(C)C(=O)c2ccc(Cl)cc2)cc1 +CC(=O)Nc1cccc(CNC(=O)C(CC(C)C)NC(N)=O)c1 +COC(=O)C1(Nc2ccccc2OC)CCOCC1 +O=c1cc(C2CCC2)ncn1Cc1ncc(-c2ccccc2Cl)o1 +Cc1cccc(C)c1NC(=O)CNC(=O)c1cc2ccccc2o1 +COc1ccc(F)cc1NC(=O)c1ccc(=O)n(-c2ccccc2)n1 +CC(NC(=O)c1cn(C)nc1C(F)(F)F)c1nc2ccccc2[nH]1 +Cc1cccc(C(=O)Oc2cccc(NC(=O)c3cccs3)c2)n1 +CCc1nc2sc3c(ncn4cnnc34)c2c2c1CCCC2 +CC1CCCCN1C(=O)CNc1ccccc1N1CCCC1=O +N#CCCN(CCC#N)C(=O)c1ccccc1Oc1ccccc1 +CCOCCCNC(=O)C1(C)Oc2ccccc2N(CC)C1=O +C#CCNC(=O)c1ccc(NC(=O)c2cc(F)cc(F)c2)cc1O +CCN(Cc1ccccc1)CC(O)c1ccccc1OC +Cn1cc(NC(=O)Nc2ccc3c(c2)CC(=O)N3)cn1 +CCc1c(C(=O)Nc2nccs2)nnn1Cc1ccccc1 +Cc1cc(C)c(NC(=O)CC(C)C(N)=O)c(Cl)c1 +O=C(NCCc1ccccc1)c1sccc1C1CC1 +O=C1CC(C(=O)NCc2ccccc2)C2(CCCCC2)O1 +CCc1nnc(NC(=O)NC(C)c2ccccc2C)s1 +O=C(CCCn1nnc2ccccc2c1=O)NCC1CC2C=CC1C2 +CC(=O)Nc1cc(S(=O)(=O)N2CCc3ccccc3C2)ccc1F +Cc1cc(NC(=O)NCC(O)c2ccccc2F)no1 +Cc1ccc(Cl)cc1NC(=O)Cn1cnnn1 +Cc1ccccc1CN(C)C(=O)CNc1cccc(C#N)c1 +Cc1cc(C(=O)OCCc2c(C)n[nH]c2C)ccc1-n1cncn1 +Cc1nnc2ccc(C(=O)N3CCOc4ccc(F)cc43)cn12 +N#Cc1ccsc1NCc1ccc(F)c(F)c1F +CC(O)CN1CCN(CC(=O)NCc2ccccc2Cl)CC1 +NC(=O)C1CCN(C(=O)c2n[nH]cc2Br)CC1 +Cc1cccc(OCC(=O)N(C)C(C)C(O)c2ccccc2)c1 +O=C(CCc1cc(F)ccc1F)Nn1cnc2ccccc2c1=O +CCCCCCNS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1 +COC(=O)NCC(OCCO)c1ccc(C)cc1 +Cc1ncsc1CN1CC(C)(C2CC2)CC1=O +CS(=O)(=O)c1ccccc1NC(=O)Cn1c(=O)oc2ccccc21 +OCCn1nnc(CO)c1CCOc1ccccc1 +COCC(NC(=O)C1CC1c1ccccc1OC)C(N)=O +Cc1cnn(CC(=O)N2CCCN(c3ccc(C#N)cc3)CC2)c1 +Cc1ncsc1CCOC(=O)C1CCCN1C(=O)C(C)C +O=C(Nc1ccccc1C(=O)NCC(F)(F)F)c1ccsc1 +CCCc1noc(CS(=O)(=O)c2ccc(Br)cc2)n1 +COc1ccccc1N1CCN(C(=O)c2ccccc2F)CC1 +Cc1cccc(C(=O)Nc2ccc(S(N)(=O)=O)c(C)c2)c1 +CC(C)(C)OC(=O)Nc1ccc(CC(=O)NCCO)cc1 +CCNC(=O)CC(c1ccccc1)c1ccccc1 +CCN(CC)C(=O)CCC(O)c1cccc(OC)c1 +CCc1nnc(COC(=O)c2ccc(-n3cccc3)cc2)o1 +CN1CC(NC(=O)CSc2ccccc2)CCC1=O +Cc1nc(-c2ccc(C(=O)Nc3ccc(F)cc3)cc2)cs1 +O=C(COc1nnc(-c2ccccc2)o1)NCCc1ccc(F)cc1 +COc1ncc(-c2nccn2Cc2ncccc2C)cn1 +COCCCN1C(=O)CCC2CN(C(=O)Cc3ccncc3)CCC21 +CCC(Nc1ccc(C(N)=O)cc1)c1ccc(F)cc1 +COc1ccc(CN(C)C(=O)c2cc(C)no2)cc1F +Cc1nc(-n2cccc2)sc1C(=O)NCC#CCN1CCOCC1 +Cc1nn2cccnc2c1C(=O)N1CCN(C(=O)C(C)C)CC1 +Cc1ccc(O)c(NC(=O)c2csc(CC(C)C)n2)c1 +Cc1cccc(CNC(=O)Cn2c(=O)oc3cccnc32)c1 +O=C(Nc1cc(-n2cccc2)ccc1F)N1CCCC1CO +CN(C)C(=O)c1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 +CCOC(=O)Nc1ccc(NC(=O)c2cc(CC)n[nH]2)cc1 +Cc1cc(C(=O)NCC(C)C)ccc1NC(=O)c1cccnc1 +CCCc1cc(=O)n(CC(=O)Nc2ccc(C(=O)OC)cc2)cn1 +O=C1CCCCN1c1cc(C#CCO)ccc1Cl +COc1cccc(CN(C)S(=O)(=O)c2ccccc2)c1OC +CCCn1c(SC(C(=O)NC2CCCCC2)C(C)C)n[nH]c1=O +Cc1cc(C)nc(N(C)CCCc2n[nH]c(N)c2C#N)n1 +Cc1cc(-n2cccc2)ccc1C(=O)NC(C)C(=O)N1CCOCC1 +COc1cc(Cl)ccc1S(=O)(=O)Nc1cccc(O)c1 +CC(CNC(=O)NCc1ccc(F)cc1)Cn1cccn1 +O=C1CCc2ccc(OCc3cn4ccccc4n3)cc21 +O=C(CCOc1ccc(F)cc1Cl)NCCO +COC(=O)c1ccccc1NC(=O)c1ccc(N)cc1Cl +CCc1c(C(=O)Nc2cc(OC)ccn2)cnn1Cc1ccccc1 +CCCCOC(=O)Cn1c(=O)oc2cccc(N)c21 +Cc1ccc(NC(=O)CSc2ccncc2)cc1S(C)(=O)=O +CCn1c(COc2ccc(Cl)cc2)nnc1SC +Cc1ccc(S(=O)(=O)N2CCOC(c3ccccc3)C2)cc1 +COCCOC(=O)CCc1cc2c(C)cc(=O)oc2cc1O +CCOC(=O)c1c(NCC(C)C)sc(C)c1C +CCn1nc(CNC(=O)c2cc(OC)cc(OC)c2)c2ccccc21 +C=CCN(CC=C)C(=O)c1ccccc1C(F)(F)F +c1ccc(CCCC2CN(Cc3ccncc3)CCO2)cc1 +CCc1cnc(N2Cc3cnc(C(C)(C)C)nc3C2)nc1 +c1csc(-c2n[nH]cc2CN2CCOC3(CCC3)C2)c1 +CCOC(=O)C1CCCN(c2c(N)n(CC)c(=O)[nH]c2=O)C1 +Cc1cccc(NC(=O)NCC(=O)Nc2cccc(-c3cn[nH]c3)c2)c1 +COc1cccc2c1OCC(C(=O)NCCOc1ccccc1F)C2 +CCS(=O)(=O)c1ccc(NC(=O)NCCCOC)cc1 +COC(=O)c1cccc(OCCn2c(C)csc2=O)c1 +CC(=O)c1ccc(OCC(=O)NC(C)(C#N)C(C)C)cc1F +O=C(Nc1cccc(C(F)(F)F)c1)NC(CO)c1ccccc1 +COc1ccc(C)cc1C(C)NC(=O)c1cc(Cl)ccn1 +COc1c(Cl)cccc1NC(=O)c1cnc2n(c1=O)CCS2 +N#CCCOc1ccc(OCc2ccccc2)cc1 +CC1CCC(C(C)C)N(S(=O)(=O)C2CCOCC2)CC1 +NC(=O)C1CCCN1C(=O)Nc1ccc2c(c1)Cc1ccccc1-2 +CCC(CC)N(CCO)C(=O)c1ccc(=O)oc1 +Cn1cc(S(=O)(=O)NCc2cccc(N)c2)cn1 +Cn1c(=O)ccn(CC(=O)Nc2nnc(C3CC3)s2)c1=O +CCN(CC)C(=O)c1ccccc1NC(=O)c1cc(C)oc1C +COc1cc2c(c(OC)c1OC)CC(CC#N)C(=O)N2 +Cc1c(CC(=O)Nc2nccs2)c(=O)oc2cc(O)ccc12 +COc1ccc(CNC(=O)CNc2ccc(-n3cccn3)cc2)cc1 +Cc1c(C(=O)c2ccccc2)oc2ccc(N)cc12 +CC(C)(CNC(=O)CNC(=O)c1ccoc1)c1ccc2c(c1)OCO2 +COc1ccc(SCC(=O)Nc2ccccn2)cc1 +Cc1ccccc1C1(CNC(=O)C2CCOCC2)CCOCC1 +Cc1cc(NC(=O)CN2CC(C)OC(C)C2)n(-c2ccccc2F)n1 +O=C(NCCOC1CCCC1)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(=O)Nc1ccc(C(=O)NC(C)c2ccc(F)cc2)s1 +N#Cc1ccc(C(=O)Nc2ccc(OCC(N)=O)cc2)cc1 +C=CCNS(=O)(=O)c1cccc(C(=O)Nc2nccs2)c1 +Cc1cc(C)n(CCCC(=O)N2CCNCC2C(=O)NC2CC2)n1 +CCN1C(=O)NC(c2ccc(OC)cc2)C(C(=O)OC)=C1C +CCCN(CCO)S(=O)(=O)c1ccc2c(c1)CC(=O)N2 +CC(C)n1ncc2c(C(=O)NCCCO)cc(-c3ccco3)nc21 +N#CC1CC(=O)N(CCOc2cccc(Cl)c2Cl)C1 +Cc1cc(C(=O)N2CCN(c3cccc(C(F)(F)F)c3)CC2)on1 +Fc1cc2c(c(F)c1F)C(c1cc(Cl)ccn1)NCC2 +CC(C)CCCNC(=O)c1cncc(C#CCO)c1 +Cn1ccnc1C(NC(=O)c1cc(Cl)c[nH]1)c1cccc(F)c1 +CCCC(=O)N1CC2(C)CN(C(=O)CCC)CC(C)(C1)C2O +Cc1ccc(C(=O)N2CCOCC2)cc1NCc1cc(C#N)cs1 +FC(F)(F)c1nnc2sc(-c3cc(-c4ccccc4)n[nH]3)nn12 +COC(=O)c1ccc(NCC(=O)N(C)Cc2ccc(F)cc2)cc1 +CCOC(=O)C1CCN(C(=O)Cc2cccc(OCC#N)c2)CC1 +COc1ccc(Br)cc1-c1noc(N)c1C +CN(CC1CCN(C(=O)OC(C)(C)C)C1)c1ncccn1 +CCOc1ccc(C(=O)NCC(=O)N(C)C2CCCC(C)C2)cc1 +CC(C1CC1)N(Cc1ccccc1)C(=O)c1cn2cccnc2n1 +COc1cccc(C(=O)N2CCN(C(=O)c3cncnc3C)CC2)c1 +CCN(CC)C(=O)CN(C)S(=O)(=O)c1c(C)cc(C)cc1C +COC(=O)c1nnn(Cc2ccc(Cl)cc2)c1N +CCCNC(=O)CNC(=O)c1ccc(NCC)nn1 +Cn1ncc2c(=O)n(CCC(=O)NCc3ccccc3F)cnc21 +CC(C)NC(=O)CCNC(=O)NC12CC3CC(CC(C3)C1)C2 +CCN(CC)S(=O)(=O)c1cc(C(=O)N(C)C(C)C)ccc1F +COc1cccc(-c2noc(CSc3nc4ncccc4[nH]3)n2)c1 +CN(CC1CCCCC1)C(=O)COc1ccc(C#N)c(F)c1 +CC1CCCN(C(=O)Nc2ccccc2SC(C)CC#N)C1 +CC(C)COC1CCN(C(=O)NC2CCCCC2C)CC1 +COC(=O)c1cc(C(=O)Nc2sc3c(c2C)CCCC3)ccn1 +C#CCNC(=O)c1nc(C)n(-c2ccc(F)cc2)n1 +Cc1cc(C(=O)NCC(C)C)ccc1NC(=O)c1cc(Cl)ccn1 +COc1ccccc1CNC(=O)Nc1cccc(N2CCNC2=O)c1 +O=C(NCCn1ccc(-c2ccncc2)n1)c1c(F)cccc1Cl +O=C(NC(Cn1cncn1)c1ccccc1)c1ccc2c(n1)CCCC2 +Fc1ccc(OCCc2nc3c(s2)CCN3)cc1F +CN(C)c1cnnc(N2CCN(C(=O)C3CC3)CC2)c1 +COc1cccc(CC(=O)Nc2ccc(S(N)(=O)=O)cc2)c1 +CCC1(CC)Oc2cc(C)ccc2N(CCCO)C1=O +CC1CCC(Nc2ccc(S(C)(=O)=O)cc2)CC1 +Cc1nc(C(C)C)sc1C(C)OC(=O)c1cc(C(N)=O)cn1C +O=C(Cc1ccccc1)NCc1noc(-c2ccco2)n1 +CCCCCC(=O)Nc1nnc(C(F)(F)F)s1 +N#Cc1ccccc1OCC(=O)Nc1ccc(CN2CCCC2=O)cc1 +NC(=O)CSc1nc(=O)n(CC2CCCO2)c2c1CCCC2 +Cc1cccc(NC(=O)c2cc3c(nc2N)CCC3)c1C +COC(=O)Nc1nc2c(s1)CN(C(=O)c1ccccc1C)CC2 +C=CCNC(=O)c1ccc(S(=O)(=O)N(CC)CC)cc1 +CCCOc1ccccc1NC(=O)N1CCNC(=O)C1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2cccc(C#N)c2)n1 +O=C(NCCC(O)c1ccccc1)c1cccs1 +COc1c(Cl)cc(Br)c2c1CCO2 +COc1ccccc1OCCC(=O)Nc1cnc2c(c1)c(C)nn2C +CNS(=O)(=O)c1cccc(C(=O)N2CCOC(C)C2)c1 +CCNC(=O)CN(CC)C(=O)c1sccc1-c1ccccc1 +C=CCNc1nc(C(=O)OC(C)C(=O)N2CCC(C)CC2)cs1 +CC(=O)Nc1cccc(NCC(=O)NCc2ccccc2C)c1 +CC1(C)CC(=O)c2c(N)nc(Nc3ccccc3)nc2C1 +CC(C)NC(=O)N1CCC2(CCC(=O)N2C)CC1 +COc1nc(C)ccc1C(=O)OCCCc1nc2ncccn2n1 +Cc1ccc(NC(=O)c2ccsc2)cc1N1CCOC1=O +Cc1cc(C#N)ccc1OC(=O)c1ncn(-c2ccccc2)n1 +Cn1cnnc1C1CCCN(C(=O)NCc2cccs2)C1 +Clc1ccc(-c2nnc3n2NCCS3)c(Cl)c1 +CC(NC(=O)NCC(C)(C)c1cccc(Cl)c1)c1nncn1C +COc1ccc(COC(=O)CC(C)c2ccc(F)cc2)cc1 +c1cnn(CC2CN(c3nnc(C4CC4)o3)CCCO2)c1 +CCn1cc(S(=O)(=O)N2CCCCC2C)cn1 +CNC(=O)NCc1ccccc1Oc1ccccc1 +COCc1ccc(CNC(=O)C2CCN(C(C)=O)CC2)cc1 +COc1ccc(-c2csc(CNC(=O)c3cc(C)n(C)n3)n2)cc1 +CN(C)C(C(=O)NCc1cn2c(n1)SCC2)c1ccccc1F +COc1cc(NC(=O)NCc2cccnc2)cc(OC)c1OC +N#Cc1ccc(CNc2cccc(C(=O)N3CCOCC3)c2)cc1 +CSc1nnc(SCC(O)c2cc(F)ccc2F)s1 +COC(=O)c1cc(CN(C)C(=O)C(C)Sc2ccccn2)oc1C +Cn1cc(C(=O)NCCc2c[nH]c3ccc(F)cc23)c(C(C)(C)C)n1 +Cn1cnnc1-c1ccc(NC(=O)CC2CCCCC2)cc1 +COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1OC +Cc1cnc2c(S(=O)(=O)N3CCCC(C(N)=O)C3)cccc2c1 +CCC1N(C(=O)c2cccn2C)CCCC12CCC(=O)N2CCOC +CN(Cc1cnn(C)c1)C(=O)C1(C)CC1(Cl)Cl +Nc1c(C(=O)NCc2ccccc2)nnn1-c1cccc(Cl)c1 +CC(C)CC1(CNC(=O)Nc2cnn(C)c2)CCCC1 +O=S(=O)(CCc1ccccc1)N(Cc1ccsc1)C1CC1 +O=C1CC(=O)Nc2cc(S(=O)(=O)Nc3ccccc3)ccc2N1 +Cc1ccc(SCC(=O)NCC(C)(O)c2ccc(F)cc2)cc1 +COc1ccc(C(=O)N(C)CC2N=CC(C)=N2)cc1N1CCOCC1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)NCc1ccncc1 +Cc1n[nH]c(C)c1NC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +CN1C(=O)C(C)(C)c2cc(-c3cnoc3N)ccc21 +CCn1ncc(-c2ccccc2Cl)c(CC#N)c1=O +COc1cc(NC(=O)C2CC3C=CC2C3)cc(OC)c1 +Cc1ccccc1OCC(O)C(=O)N1CCc2c(nc[nH]c2=O)C1 +CC(C)C(=O)N1CCCN(C(=O)c2ccccc2OCC2CC2)CC1 +O=C(c1cccnc1N1CCCC1)N1CCOC(c2ccccc2)C1 +COc1cc(C#N)ccc1OC(C)C(=O)Nc1ccc(C)cc1F +O=c1[nH]c(Cc2ccccc2Cl)nc2ccsc12 +CCOC(=O)c1c(-c2ccncc2)oc(N)c1-c1ncc[nH]1 +CCn1cc(C(=O)NC2CCN(C(=O)C3CCCCC3)CC2)cn1 +Cc1ccc2[nH]c3c(=O)n(CCC#N)ncc3c2c1 +Cc1ccc(N2CCC(NC(=O)Nc3ccccc3C)C2=O)cc1 +CCOc1ccc(OCC(=O)NCC#Cc2ccc(OC)cc2)cc1 +COc1ccc(C(=O)N2CCC(Cn3cnc4ccccc43)CC2)cc1 +COCCN(CC(C)C)C(=O)Nc1ccc(F)c(C#N)c1 +CC(C)C(NC(=O)c1ccccc1F)C(=O)N(C)Cc1ccsc1 +CCc1n[nH]c(C2CN(C(=O)c3c(C)noc3C)CCO2)n1 +Cc1cccc(N2CC(C(=O)N(C)Cc3ccccc3)CC2=O)c1 +COC(=O)c1sc(NC(=O)c2cc(C(C)C)[nH]n2)nc1C1CC1 +CCCc1nnc(NC(=O)N(C)CCC#N)s1 +CN(Cc1ccc(O)cc1)C(=O)CCc1ccsc1 +O=c1c2ccccc2nc2n1CCC2(Br)Br +Cc1cc(C(=O)Nc2ccc(F)c(F)c2F)on1 +CC1CCCCN1c1ncnc(N2CCCCC2C)c1N +CCc1cc2c(cc1C(=O)CCN1CCOCC1)OCCCO2 +CCN(CC(=O)Nc1c(F)cccc1F)C(=O)c1cccc(F)c1 +CNC(=O)c1cc(Cl)ccc1NC(=O)Cc1ccc(OC)cc1 +COc1ccc(-c2noc(C(=O)NCc3ccccn3)n2)cc1 +CN1C(=O)COC2CN(S(=O)(=O)Cc3ccccc3)CC21 +COC(=O)c1c(SCC(=O)Nc2ccccc2)nc(=O)[nH]c1C +Cc1cccc2c(=O)n(CC(=O)N(C)CCC(C)C)cnc12 +CCn1cc(S(=O)(=O)NCc2cccc(C)c2)c2cccnc21 +CC(C)c1csc(NC(=O)CC2OCCc3ccsc32)n1 +Cc1ccc2cc(NC(=O)C3CC(=O)N(Cc4ccco4)C3)ccc2n1 +CC1(C)CC2CC(C)(CN2C(=O)Nc2cnc3sccn3c2=O)C1 +O=c1[nH]ncc(NCc2csc3ccccc23)c1Cl +CCOC(=O)c1ccc(OC(=O)c2ccn(C)c(=O)c2)cc1 +O=C(Cc1ccc(F)cc1)NC1CCCc2ccccc21 +CCCN(C)C(=O)Nc1ccc(N(C)C(=O)OC)cc1 +Cc1ncsc1C(=O)N(C)Cc1ccc(F)c(F)c1 +Cc1nc(CC(=O)N2CCN(c3nc4ccccc4o3)CC2)cs1 +COc1cc(OC)c2cc(C(=O)Nc3ccnc(C)c3)[nH]c2c1OC +CCCCC(=O)Nc1cc(OC)ccc1NC(C)=O +O=C1CN(C(=O)c2ccc(-n3cccc3)cc2)CCN1 +CCN1CC(C(=O)NCCCc2cccc(C)c2)CC1=O +Fc1ccc(-c2cc(CNCCc3ccco3)c3nnnn3c2)cc1 +NC(=O)c1ccc(OCC(=O)N2CCc3ccccc3C2)cc1 +Cc1ccccc1CN(Cc1cccnc1)C(=O)c1cc[nH]n1 +CCOc1ccccc1NC(=O)CSc1nn2cnnc2s1 +CC(=O)N1CCN(C(=O)CCSc2ccc(C)c(C)c2)CC1 +COC1CCCN(Cc2cnc3ccc(C)cn23)C1 +CNC(=O)NCC(=O)N1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +NC(=O)C(NC(=O)CN1CCc2sccc2C1)c1ccccc1 +CN(Cc1ccsc1)C(=O)c1ccc2c(c1)OCC(=O)N2 +COCC1(C(=O)NCCc2cccc(F)c2)CCC1 +CCC1(CC)C(NC(=O)NC2C=CC(CO)C2)C(C)C1OC +Cc1[nH]nc(O)c1C(c1cccnc1)C(C#N)C#N +CCOc1ccccc1CNC(=O)c1cccc2ncccc12 +NS(=O)(=O)c1ccc(NCc2ccncc2)cc1 +Cn1ncc2c(N3CCC(Nc4ccc(F)cc4)CC3)ncnc21 +CCC(OC)C(=O)Nc1ccc(-n2ccnc2)cc1 +CN(C)c1ccc(C(=O)Nc2ccc(F)c(F)c2)cn1 +O=C(CNC(=O)c1ccc2cc[nH]c2n1)NCc1cccnc1 +CCn1c(=O)sc2cc(NS(=O)(=O)CC)ccc21 +NC(=O)c1cc(NCC(=O)N2CCCc3ccccc32)ccc1F +O=C(COc1cccc2ccccc12)Nc1cccnc1 +CC(=O)Nc1ccc(CC(=O)N=c2[nH]nc3ccccn23)cc1 +Cc1cc(C)n(CCNS(=O)(=O)N2CCCCC2)n1 +CC(=O)N1CCc2ccc(NC(=O)c3c(C)nc4ccccn34)cc21 +COc1ccccc1C(C)(C)CNC(=O)NCC1CC1 +CNC(=O)NCC(=O)Nc1ccccc1SCC(C)C#N +Cc1nn(C)c(C)c1NC(=O)CSc1nccn1C +COc1ccc(CC2CCCN2c2ncnc3c2cnn3C)cc1 +COc1ccc2nc(N3CC(C(=O)NC(C)C)C3)sc2c1 +CCCc1noc(C(C)N2CCCC(c3nc4ccccc4o3)C2)n1 +Cc1ccc(C(C)(C)C(=O)Nc2ccc(C(N)=O)cc2)cc1 +CC(C)CNC(=O)C(NC(=O)c1ccc2cnsc2c1)C(C)C +Cc1ccc(C(=O)Nc2nnc(-c3cc(C)nn3C)o2)cc1 +CNC(=O)c1cccc(NC(=O)c2ccnc(C)n2)c1 +O=C(COC(=O)C1CC1)Nc1ncc(Cl)cc1Cl +N#Cc1ccccc1NC(=O)Cc1cccc(Cl)c1 +CCNC(=O)CN(CC)C(=O)COc1ccc(Br)cc1 +CCOC(=O)c1cc(C)sc1NC(=O)CSc1ncccn1 +CCCN(C(=O)CS(=O)(=O)c1ccccc1)c1cccc(C)c1 +CCc1noc(C)c1C(=O)OCC(=O)Nc1ccc(C)cc1Cl +O=C(Nc1ccc(-n2ccnc2)cc1)c1ccc(Cl)c(Cl)c1 +CC(C)CCN(CCC#N)S(=O)(=O)N1CCCCC1 +Cc1ccc2ncc(C(=O)NC3CCN(CC(F)(F)F)C3=O)n2c1 +CCN(CC)C(=O)Nc1ccc(OC(C)C)cc1F +CC(C)C(=O)NCC1CCCN(C(=O)CC2CCCCC2)C1 +COC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)c1cccn1C +COC(=O)C1CCN(C(=O)c2c[nH]nc2-c2cccc(Cl)c2)CC1 +CCOC(=O)Nc1ccc(NC(C)C(=O)NC(C)(C)C)cc1 +Cn1ccc2c(C(=O)NCCc3c[nH]c4ccccc34)cccc21 +CCOC(=O)c1cc2c(ccn2C)n1CC(=O)N(C)C +Cc1c(N)cc(C(=O)N2CCOC(C)(C)C2)cc1F +CCC(Cc1ccc(C)cc1)NC(=O)NCc1ncn(C)n1 +CC(=CCNc1ncnc2c1ncn2CCC#N)CO +CCN(Cc1ccccn1)Cc1nc(-c2ccccc2)cs1 +CCOC(=O)c1c(C)[nH]c(C)c1-c1csc(NC2CC2)n1 +CCNC(=O)c1nsc(C(=O)N2CCCC2)c1N +COCCOc1ccccc1NS(=O)(=O)c1cn[nH]c1 +COc1ccc(NC(=O)CCCOC2CCCC2)c(N)c1 +Cc1ccc(C(C)NC(=O)Nc2ncn(Cc3ccccn3)n2)o1 +CC1CCCN(C(=O)c2ccc(-n3cncn3)nc2)C1 +COc1ccc(NC(C)c2nc(C(C)C)no2)cn1 +CCC(CC)N(CCOC)C(=O)C1CC(=O)Nc2ccccc21 +Fc1cc2c(c(F)c1Cl)CCNC2c1cncs1 +O=C(c1occc1-c1ccccc1)N1CCN(c2nccs2)CC1 +CC(C)n1cc(C(=O)c2cc(F)ccc2O)cc(C#N)c1=O +O=C(Cc1c(F)cccc1Cl)Nc1ccncc1 +CCC(C)Cn1c(C(C)NC(=O)COC)nc2ccccc21 +CCNS(=O)(=O)c1cccc(C(=O)Nc2cc(C)cc(C)c2)c1 +Cn1nc(-c2cccs2)cc1C(=O)Nc1ccc2c(c1)OCCO2 +O=C(NC(c1ccccc1)C1CCC1)N1CCCC2(C1)OCCO2 +COc1ccc(O)c(C(=O)N(CCO)C2CC2)c1 +O=C(COc1ccc(Cl)cc1)OCCN1CCOCC1 +CNc1snc(C)c1C(=O)N1CCN(Cc2ccccc2)CC1 +O=C(NCCCc1ccccc1)C1CN(C(=O)c2cnccn2)C1 +O=C(CSc1ccc(-c2cccnc2)nn1)NCc1ccccc1 +COc1ccc2cc(C(=O)NC3CCCCC3)c(=O)oc2c1 +O=C(NCCNC(=O)c1ccc(O)cc1)Nc1c(F)cccc1F +O=C(CCn1cccc1)Nc1ccc2c(c1)OCO2 +CCOc1ncccc1C(=O)N1CCN(Cc2cccc(C)c2)CC1 +CCS(=O)(=O)NCC12COCC1CN(c1cc(OC)ncn1)C2 +Cc1cc(Cl)ccc1NC(=O)C12CCC(C1)C(C)(C)C2=O +CCC(C)C1NC(=O)C2CC(NC(=O)Nc3ccccc3)CN2C1=O +COC(=O)c1ccc(-c2nc[nH]c2-c2ccoc2)cc1 +Cc1ccc(C(=O)CCC(=O)N2CC(=O)Nc3ccccc32)cc1C +CS(=O)(=O)N1CCC(C(=O)NCc2ccoc2)CC1 +COc1ccc(NC(=O)c2cc(Cl)cn2C)cc1N1CCCC1=O +COCC(NC(=O)c1c(O)cc(F)cc1F)C(N)=O +COCCNC(=O)c1cccc(NCC(=O)N2CCCCC2)c1 +Cc1cc(C(=O)OC(C(N)=O)c2ccc(F)cc2)on1 +Cc1ccc2c(CC(=O)OC3CCCCC3=O)coc2c1 +Cc1cccnc1NC(=O)c1cc(=O)c(OCc2ccccc2)co1 +Cc1ccccc1CC(C)NC(=O)N1CCOC(C)C1 +C#CCn1c(=NC(=O)c2ccnn2C)sc2cc(F)cc(F)c21 +Cc1cc(C)c(CNC(=O)C(CC(C)C)NS(C)(=O)=O)c(=O)[nH]1 +COc1ccc(C(=O)Nc2ccc(N)c(C)n2)cc1OC +CC1(C)CC(=O)c2cnc3nc(N4CCCCC4)[nH]c(=O)c3c2C1 +COc1ccc(SCC(=O)c2sc3ncnn3c2C)cc1 +CCOC(=O)NCCC(=O)Nc1ccc(-n2nc(C)cc2C)nc1 +C=CCNC(=O)COc1ccc(S(=O)(=O)N(C)C)cc1C +O=C(Nc1ccc(F)cc1)C1CC(=O)N(C2CCOCC2)C1 +Cc1cc(NC(=O)COc2ccc3ccc(=O)oc3c2)no1 +Cc1[nH]ncc1CCCNC(=O)c1cc(Cl)cc2cccnc12 +Cc1ccc(-c2cnnn2CCOc2cccc(N)c2)cc1C +Cc1nccn1-c1ncccc1NC(=O)Cc1ccc(F)c(F)c1 +CCc1ccc(C(=O)C2CCCN2S(=O)(=O)CC)cc1 +Cc1cc(C(=O)N2CCC(C(N)=O)C2)nn1-c1ccccc1 +COc1ccccc1N(C)CC(=O)c1c[nH]c2ccccc12 +Cc1cc2nc(-c3cccc(N)c3)n(CCO)c2cc1C +CCC1CCCCN1C(=O)c1cccc(Cl)c1 +Cn1cc(CCNC(=O)c2cc3ccccc3nc2N2CCCC2)cn1 +CCCCC(=O)Oc1cccc(N2CCCC2=O)c1 +CC(=O)c1ccc(OCC(=O)N(Cc2ccccc2)C(C)C)cc1F +CCOCCOC(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +Cn1cc(C(=O)NCc2cccc(OCC(F)F)c2)ccc1=O +O=C(c1cccnc1)N1CC(S(=O)(=O)NC2CCCC2)C1 +COCCN(Cc1ccc(F)cc1Cl)Cc1c(C)noc1C +Fc1cnccc1C1NCCc2c(Cl)cccc21 +COc1ccc(C(=O)N2CCc3c(nc[nH]c3=O)C2)cc1O +Cn1c(NC(=O)COc2ccc3c(c2)CCC3)cc(=O)n(C)c1=O +Cc1occc1C(=O)NC1CCN(c2snc3ccccc23)CC1 +COC(=O)NCC(=O)N(C)CCOc1ccccc1C +O=C(CSc1ncc2ccccn12)Nc1ccc(F)cc1 +C=CCOc1ccc(C2NC(=O)NC(C)=C2C(=O)OCC)cc1 +C#CCCNC(=O)NC1CCN(CC(F)(F)F)C1 +CN1CC(=O)N=C1Nc1cc(N)n(-c2ccc(Cl)cc2)n1 +CCCn1c(C(C)C)ccc(-c2nnc(NCC)s2)c1=O +NS(=O)(=O)c1ccc(NC(=O)COc2ccc(Cl)cc2)cc1 +CC(Cn1nnc2ccccc21)NC(=O)Cn1nnc2ccccc21 +Clc1ccc2c(N3CCCC3c3cccnc3)ncnc2c1 +CC(=O)N(C)c1ccccc1NC(=O)c1ccncc1F +Nn1c(SCC(=O)NC2CCCCCC2)nnc1C(F)(F)F +Cc1cc(C)c(CNC(=O)COc2ccc(F)c(Cl)c2)c(=O)[nH]1 +CN(C)c1cc(OC2CCN(C(=O)c3cnccn3)C2)ncn1 +O=C(NCCCc1ccccc1)c1ccc(F)nc1 +CC(C)CCCC(C)NC(=O)NCc1cccnc1 +Cn1c(C(=O)N2CCC(NS(C)(=O)=O)CC2)cc2ccccc21 +Cc1ccccc1C(NC(=O)c1cnn(C)c1)c1ccncc1 +CCC(=O)Nc1ccc(NC(=O)CNS(C)(=O)=O)cc1 +O=C(c1ccn(-c2ccccc2)n1)N1CCc2ccccc2C1 +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)C1CCCN1C(=O)c1ccco1 +Cn1ccc(C(=O)Nc2cccc(Cl)c2F)cc1=O +Cc1cccc(C)c1NC(=O)COC(=O)c1ccc(Cl)c(N)c1 +Cc1cc(NC(=O)CSc2nc(C)c(C)c(C)c2C#N)n(C)n1 +Cc1nn(C)c2sc(C(=O)N3CCN(CC(C)C)CC3)cc12 +Cc1ccc(C(=O)N2CCc3ccccc32)cc1N +CN(Cc1ccncc1)C(=O)NCC1(c2ccc(F)cc2)CC1 +Cc1nc(NC(=O)Cc2c(C)nn(C)c2C)sc1-c1nccn1C +COc1cc(Cl)ccc1C(=O)N(C)Cc1ncnn1C +O=C(NC1CCSc2ccccc21)c1cccc(F)c1 +Cc1nnc(SCCc2ccccc2Cl)n1CC(N)=O +NC(=O)CSc1nnc(-c2ccccc2)n1CCO +CCC(=O)N1CCN(c2nc3ccccc3nc2C(F)(F)F)CC1 +O=C(CSc1nnnn1C1CC1)NCc1ccoc1 +Cn1cc(NC(=O)NC2CCCCC2)c(C(N)=O)n1 +Cc1ccc(CN2C(=O)C3(OCCO3)c3cc(C)ccc32)cc1 +NC(=O)C1CC(=O)N(c2ccc(OCc3ccc(F)cc3)cc2)C1 +COC(=O)C1CCN(CC(=O)c2cc(C)n(C3CC3)c2C)CC1 +O=C(Nc1ccc(-n2cnc3ccccc32)cc1)c1ccc[nH]c1=O +Cc1csc(=O)n1CCC(=O)NC1(c2cccc(Cl)c2)CC1 +Cc1cccc2nc(C(=O)N3CC(C)CC(C)C3)cn12 +O=C1CCCCCC1Sc1nnc(-c2cccs2)o1 +O=C1CCc2ccccc2N1Cc1nc(Cc2ccccc2)no1 +Cc1cc(=O)c2cc(NC(=O)c3cccc(F)c3)ccc2[nH]1 +NC(=O)C1CCCN1C(=O)c1cccc2c1OCO2 +Nc1nc(N)nc(COC(=O)C2(c3ccc(F)cc3)CCCC2)n1 +COc1ccc(NC(=O)Cc2ccc(-n3cccc3)cc2)cc1 +COCC(C)CNC(=O)NC1CCCc2c1cnn2C +O=C(C1CC1)N1CCC(c2nccnc2Oc2cccnc2)CC1 +C#CCN1CCN(C(=O)NCCC2Cc3ccccc3C2)CC1 +Nc1cc(Cl)ccc1NC(=O)c1ccc(F)c(F)c1F +Cc1ncc2c(n1)CN(Cc1cc(F)cc3cccnc13)CC2 +O=C(Nc1cccc2cnccc12)c1cc(Cl)c2c(c1)OCCO2 +Cc1nnc(Oc2ccc(F)cc2F)c(C#N)c1C +CCCOc1ccc(CCC(=O)N(C)C)cc1N +COC(=O)Cc1csc(NC(=O)N(C)Cc2ccccc2)n1 +CC(=O)NC1CCOc2c(F)cc(C(O)C(C)(C)C)cc21 +CC(Cc1cccs1)C(=O)N1CCC(O)c2ccccc2C1 +Cn1c(C(=O)N(CCC(N)=O)Cc2ccccc2)cc2ccccc21 +CCc1ccc(OC)c(C(C#N)CC(=O)N(C)C)c1 +NC(=O)c1cccc(S(=O)(=O)NCCc2c(F)cccc2F)c1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1cc(-c2ccccc2)[nH]n1 +CCc1ccc(C(=O)N(C)c2cc(F)ccc2F)o1 +O=C1C(Sc2nc(=O)ccn2C2CC2)CCN1c1ccccc1F +COc1ccc(NC(=O)COC(=O)c2cc(C)oc2C)cc1Cl +CCC(NCc1c[nH]nc1-c1ccc(F)cc1)c1nc(C)no1 +CCC(=O)N(Cc1nccn1Cc1ccc(F)c(F)c1)C1CC1 +CC(=O)NCC1CCCN(S(=O)(=O)c2ccc(C)c(C)c2)C1 +Cc1cc2ccccc2n1CC(=O)NCc1cc(F)cc(F)c1 +COc1ccc(Nc2ncc(N)cc2OC)cc1OC +Cc1ccc(C(C)(O)CNC(=O)c2sccc2-n2cnnn2)o1 +Nc1cc(S(=O)(=O)NC2CCCC2)ccc1F +N#CC(C(=O)CSc1ccc(Cl)cc1)c1nc2ccccc2[nH]1 +COC(=O)c1ccc(Cn2cc(Br)ccc2=O)cc1F +COc1cccc(OCC(=O)Nc2ccc(N3CCCC3)nc2)c1 +CC1CCCCN1C(=O)CN(C)C1=NS(=O)(=O)c2ccccc21 +CC1(C)CCCN1C(=O)c1cc(Cl)cc(Cl)c1 +Cn1cc(-c2nc(C(=O)OCCOc3ccccc3)cs2)cn1 +Cc1cc(C(=O)NC(C)c2cccc(C(F)(F)F)c2)c(C)o1 +CCNC(=O)N1CCCC(c2nnc(-c3ccc(OC)cc3)s2)C1 +Cc1ccc2nc(CN3CCC(C(=O)Nc4ccon4)CC3)[nH]c2c1 +Cc1ccccc1COC1CN(S(=O)(=O)Cc2ccccc2)C1 +CCCN(CCC)C(=O)C1CCN(c2nccc(OC)n2)CC1 +COc1ccccc1CNc1nc(C)c(C(C)=O)s1 +O=C(CNC(=O)N1CCN(c2ccccc2)CC1)NCC1CCCO1 +N#Cc1ccc(NC(=O)C2CC(=O)N(C3CC3)C2)cc1Cl +O=C(Nc1cccnc1)c1csc(-c2ccsc2)n1 +CCOc1cc(C2NC(=O)NC(C)=C2C(=O)OC)ccc1OC +COC(=O)C(C)(C)NC(=O)Cc1cc(=O)oc2cc(OC)ccc12 +O=S(=O)(c1c[nH]cn1)N1CCCC1c1ccco1 +COc1cc(C)ccc1OC(=O)CSc1ccc(C#N)cc1 +CCOC(=O)Cn1c(C(=O)OC)cc2ccccc21 +CCCCNS(=O)(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +CCn1c(Cn2ccnc2)nnc1C1CCN(S(C)(=O)=O)CC1 +CC(Cc1ccccc1F)NC(=O)C1CC(=O)N(C)C1 +CC(O)(CNC(=O)Nc1ccc(C(C)(C)C)cc1)CN1CCOCC1 +CCOC(=O)N(C)c1ccc(NC(=O)C(C)CC)cc1 +COc1ccc(CN2CCN(C(=O)C3CC4CCC3C4)CC2)cc1F +Cc1nn(-c2ccccc2)c(C)c1CNCCc1ccccc1 +COC(=O)c1ccc(NC(=O)c2cc3occc3n2C)cc1 +Cc1cccc(NC(=O)C(C)c2cccs2)c1C(N)=O +O=C(CNS(=O)(=O)c1ccccc1)NCCc1ccccc1 +Cc1nc(CNC(=O)NCC(C)Nc2ccccc2)no1 +O=c1oc(=O)n(CCCOc2ccc(Cl)cc2)c2ccccc12 +NC(=O)c1ccnc(N2CCC(Oc3ccc(F)cc3)CC2)c1 +Cc1ccc(-c2ccc(C(=O)N3CCCCC3)c(N)n2)c(C)c1 +Cc1cccc(C(=O)NCC#CCOc2cccnc2)c1 +Cc1ccc(N)c(Nc2ccc(C(F)(F)F)cc2)n1 +CNc1oc(-c2ccccc2F)nc1S(=O)(=O)c1ccccc1 +O=C(CCc1nccs1)N1CCN(c2cccnn2)CC1 +CCn1c(SCCCC#N)nnc1-c1ccc(OC)cc1 +CC(C)n1nc(-c2ccccc2)cc1NC(=O)NCC(=O)NC1CC1 +COc1ccc(CO)cc1OCCc1ccccc1 +CCC(=O)c1ccc(OCC(=O)N(CC)C2COCC2O)cc1 +CC1CCCCC1N(C)C(=O)COc1ccccc1C(N)=O +COc1cccc(C2CC(=O)Nc3cc(OC)cc(OC)c32)c1 +O=C(Nc1ccc2c(c1)OCCO2)C1CCCCC1 +Cc1cnc(NC(=O)C(C)n2cc(Br)c(C)n2)s1 +CC(C)OC(=O)c1ccc(CSc2n[nH]c(N)n2)cc1 +CCOC(=O)N1CCC(C(=O)NCC2(c3ccccc3)CC2)CC1 +Cc1cccc(C(C#N)N(C)C(=O)c2cccc(F)c2)c1 +Cc1ccc(NC(=O)NCC(O)c2ccco2)c(Cl)c1 +CC(NS(C)(=O)=O)c1ccc(NC(=O)c2ccc(F)cc2)cc1 +CN(CCCO)S(=O)(=O)c1ccccc1Cl +Cc1nn(C)c(C)c1OS(=O)(=O)c1cnn(Cc2ccccc2)c1 +CCc1nnc(SCC(=O)Nc2ccccc2SC)n1N +CS(=O)(=O)N(Cc1cnc2ccccn12)c1ccccc1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)c1ccncc1F +CC(=O)Nc1ccc2c(c1)CCC(=O)N2CC(C)C +N#Cc1nccnc1-c1ccc2c(c1)NC(=O)CS2 +CCCC(C)(CO)NC(=O)NCCc1ccccc1Cl +O=S(=O)(NCc1cn(-c2ccccc2)nn1)N1CCCCCC1 +CC1(C)CCC(CNC(=O)CCn2cnc3ccccc3c2=O)CC1 +Cc1cccc2[nH]c(CNC(=O)N3CCc4cc(F)ccc4C3)nc12 +Cc1cc(N2CCC(c3cc(=O)n(C)[nH]3)CC2)ncn1 +CCOc1cccc(-c2cnn(CC)c(=O)c2CO)c1 +CC(C)Cc1cc(C(=O)NC(CO)C(N)=O)n(C)n1 +Cn1cc(CCNC(=O)Nc2ccc(F)c(C(F)(F)F)c2)cn1 +CCOc1cc(C(=O)Nc2ccc(C)cc2F)ccc1OC +CCCn1ccc2cc(NC(=O)NCCNC(=O)N(C)C)ccc21 +CCn1nc(C)c(NC(=O)c2cc(C)nc(N(C)C)n2)c1C +COc1ccc(C)cc1C(O)CN1CC(C)OC(C)C1 +COC1(CNC(=O)c2cc(C)n[nH]2)CCOCC1 +Cn1nccc1C(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +COC(=O)c1cccc(C(=O)Nc2ccc(-c3nncn3C)cc2)c1 +CCC(Oc1ccc(Br)cc1)C(=O)NCc1ccco1 +O=C(Nc1ccc(SCc2cccnc2)cc1)C1CCC1 +N#Cc1ccsc1NC(=O)Cn1nnc2ccccc2c1=O +CN(C)C(=O)C1CCN(C(=O)c2c(F)cccc2F)CC1 +O=C(c1cccc(-n2cnnn2)c1)N1CCn2c1nc1ccccc12 +CC(C)NC(=O)NCc1ccc(N2CCCCC2=O)cc1 +Cc1cc(C(=O)NC(C)c2ccccc2Cl)c(C)o1 +Cc1nc2ccccc2n1CCNC(=O)c1cc2ccccc2oc1=O +COc1ccc(Nc2cccc(NC(C)=O)c2)cc1F +CC1=NC2(CCC3CN(S(=O)(=O)C4CC4)CC32)C(=O)N1C +CCOc1cc(C)c(-c2nnc(CCO)o2)cc1Cl +COC(=O)c1cccc2oc3cc(CO)cc(O)c3c(=O)c12 +Nc1cccc2ccc(CC(=O)N3CCCCCC3)nc12 +O=C(NCc1nc2ccccc2s1)Nc1cnn(CC(F)F)c1 +COc1ccccc1C(=O)NCCN1Cc2ccccc2C1=O +O=c1ccc2c([nH]1)CCN(Cc1ccncc1)CC2 +COc1ccc(CCC(=O)Nc2cnn(-c3ccccc3F)c2)cc1 +NC(=O)c1ccc(CNC(=O)Nc2ccc3c(c2)COC3)o1 +CCOC1CCN(C(=O)NCCOc2ccc(F)c(F)c2)CC1 +CC1CCC(C(N)=O)CN1C(=O)Cc1cccc2ccccc12 +CCC1CCCN(C(=O)Nc2nnc(C(F)(F)F)s2)C1 +CC(O)CN1CCN(C(=O)c2ccc(OCC3CC3)cc2)CC1 +COCCNC(=O)NCc1noc(-c2ccco2)n1 +Cc1nn(CC(=O)Nc2cc(-n3cnnn3)ccc2F)c(C)c1Cl +CC(O)(CNC(=O)c1ccc(C#N)cc1)c1ccc2c(c1)OCO2 +Cc1nc(CNC(=O)NCc2cc(Cl)cc3c2OCC3)oc1C +CC(C)(C)C(=O)N1CCCN(c2ccccc2S(C)(=O)=O)CC1 +Cc1cnc(-c2nc(CCc3ccccc3)no2)cn1 +Cc1csc(N(C(=O)CCc2nc3ncccc3[nH]2)C2CC2)n1 +C#CCOC(=O)c1csc(-c2ccc(F)cc2)n1 +CCN(C(=O)CS(=O)(=O)c1ccccn1)C1CC1 +CC(=O)N1CCC2(CC1)OC(=O)C(C)=C2C(=O)NCc1ccccc1 +CC1CCCC(N(C)C(=O)CCCNC(=O)C2CC2)C1 +CC1CN(CCNc2cncc(-n3cncn3)n2)CC(C)O1 +Cc1cc(C(F)(F)F)nc(CCn2cc(C3CCOC3)nn2)n1 +CCOC(=O)c1cccc(NCc2cn3c(C)cc(C)nc3n2)c1 +COCc1ccccc1C(=O)N1CCCC(CNS(C)(=O)=O)C1 +CCC(CC)N(C)C(=O)NCc1cnn(-c2ccccc2)c1 +O=c1n(Cc2cccc(F)c2)nc2nc(N3CCCC3)ccn12 +CC(NS(=O)(=O)c1cccc2cnccc12)c1ccc(F)c(F)c1 +O=C(NCC1CCN(c2ccc(F)cc2)C1)c1cc[nH]n1 +Cn1cc(C(=O)N(Cc2ccco2)CC2CCCO2)cn1 +Cc1nc(-c2ccccc2)n(CC(=O)NC(C)C)n1 +COc1cc(CN2CCN(C(=O)CC(C)C)CC2)cc2c1OCO2 +CC(=O)N(C)CC(=O)Nc1ccc(Oc2ccc(Cl)cc2)nc1 +COc1cc(OC)cc(C(=O)N2CC(OCc3ccc(F)cc3)C2)c1 +COc1ccccc1C(C)CC(=O)Nc1ccccc1C(C)=O +CCC1CCC(NC(=O)CNS(=O)(=O)c2cnn(C)c2)CC1 +CCc1oc(C(=O)NC2CCCN(Cc3ccccc3)C2=O)cc1C +CC(OCC1CC1)C(=O)Nc1cccnc1N(C)C +CC(C)Cn1cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)c2ccccc21 +Cc1ccc(NC(=O)Cc2noc3c(C)cc(N)cc23)cc1C +Cc1ccc(N(C)C(=O)c2cc(-c3cccnc3)on2)c(C)c1 +O=C(NCc1ccncc1)c1c(-n2cnnn2)sc2c1CCCC2 +CC(C)(C)C(=O)Nc1nn2c(-c3cccc(F)c3)nnc2s1 +COC(=O)C1CN(C(=O)NC(C)C)CCN1C(=O)C1CCCCC1 +CC(C)Cn1c(=O)oc(=O)c2cc(Br)cc(Cl)c21 +Cc1cccc(NC(=O)c2ccc(S(=O)(=O)NC(C)C)cc2)c1C +Cc1sc(=O)n(CC(=O)NCC2(c3ccccc3)CC2)c1C +N#CCC(=O)Nc1ccc(Oc2ccccc2)cc1 +Cc1ccc2nc(NC(=O)COc3ccccc3)oc2c1 +COC(CNS(=O)(=O)c1ccc(F)cc1)c1ccc(C)s1 +C=CCNC(=O)Cc1cc(-c2ccc(Cl)cc2)on1 +Cc1noc(C)c1CC(=O)NCC#Cc1ccccc1 +CC1CCCC(NC(=O)CCc2nc(-c3ccncc3)no2)C1C +Cc1ccnc(NC(=O)c2ccc(CSc3nccn3C)o2)c1 +Cc1cccc(N(C)S(=O)(=O)c2cccc(C(N)=O)c2)c1C +COc1cccc(OCC(=O)Nc2ccc(C)cc2)c1 +Cc1ccn2c(=O)c(C(=O)Nc3ccc(C)c(F)c3)cnc2c1 +CN=c1scc(-c2ccc(NC(C)=O)cc2)n1C +O=C(c1nc2ccccc2s1)N1CCN(c2ccccc2)CC1 +CCN(C(=O)NC1CCN(C(=O)c2ccco2)CC1)C1CCCC1 +CCNC(=O)C1CCN(C(=O)C2CC(=O)N(c3ccccc3)C2)CC1 +O=C(NCCN1CCOCC1)N(CC1CC1)C1CCCCC1 +COc1ncccc1C(=O)NCC#Cc1ccccc1C(F)(F)F +Cc1c(CNC(=O)Nc2ccc3c(ccn3CC(C)C)c2)cnn1C +CCCCNC(=O)C1CCCN(C(=O)c2ccoc2)C1 +CC(C)(C)CCC(=O)Oc1ccc(-n2cnnn2)cc1 +O=C(CN1C(=O)COc2ccccc21)Nc1ccc2c(c1)OCO2 +CC(C)(C)CCC(=O)NCc1ccc(C#N)cc1F +Cn1ncc(C(=O)NCc2ccc(Cl)cc2)c1-n1cccc1 +COc1ccc(NC(C)=O)c(NC(=O)c2cn[nH]n2)c1 +CC(c1ccccc1)N1CC(C(=O)Nc2cccc(F)c2)CC1=O +Cc1cc(C)n2nc(C(=O)N3CCCC(n4cncn4)C3)nc2n1 +O=C(NCc1nnnn1-c1ccccc1)C1CCCCC1 +CC(Oc1ccccc1Br)C(=O)Nc1ccc(O)cc1 +CCC(=O)Nc1cccc(NC(=O)C(C)OCC(F)(F)F)c1 +O=C(NC(CO)Cc1ccccc1)c1ccc(C(F)(F)F)cc1 +CCSc1ccc(Cl)cc1NC(=O)N1CC(O)CC1CO +CC(=O)c1ccc(NC(=O)NCc2ccnn2C)cc1 +Cc1c(C(=O)NCCCC(N)=O)sc2cccc(F)c12 +Cc1cccnc1NC(=O)Cn1ncc(=O)c2ccccc21 +O=C(NCCOCCO)c1ccc(C(F)(F)F)nc1 +CSc1ccc(C(=O)Nc2nnc(-c3sc(C)nc3C)o2)cc1 +CC(C)c1noc(C(C)Oc2ccc(S(C)(=O)=O)cc2)n1 +Cc1ccc2c(c1)c(=O)c(C(=O)Nc1ccc(C(N)=O)cc1)nn2C +Cc1cc(NCc2ccc(Cl)cc2)n2ncnc2n1 +CC(C)c1ccc(-n2nnc(-c3nc(-c4ccccn4)no3)c2N)cc1 +CCOC(=O)CNC(=O)NCc1ccc(SC)cc1 +COc1c(O)ccc(C=Cc2cc(O)cc(O)c2)c1O +CC1CCN(C(=O)C2(c3ccc(F)cc3F)CCC2)CC1O +O=C(Nc1ccc2c(c1)COC2)c1ccc(C(F)(F)F)nc1 +COc1ccc(-n2ccnc2S(C)(=O)=O)c(OC)c1 +Nc1nc(CN2CCOCC2)nc(N2CCOCC2)n1 +CCCNC(=O)c1ccc(F)c(S(N)(=O)=O)c1 +CCN1CCN(C(=O)C2(C)Cc3ccccc3C(=O)O2)CC1 +CSc1ncccc1C(=O)N1CCC(=Cc2ccccc2F)CC1 +Cc1cc(OCc2n[nH]c(SCC(N)=O)n2)ccc1Cl +Cn1cnc(S(=O)(=O)N2CCC(c3ccccn3)CC2)c1 +Cc1ccccc1C(N)C(=O)NCCCOC(C)C +O=C(Nc1cn[nH]c1)c1ccc2ccc(Cl)cc2n1 +COc1cc(C(C)O)ccc1OCC(=O)OC(C)C +Cc1ccc(OCC(=O)N2CCCC2(C)C)cc1C +[H]N=c1n(CC=C)c2ccccc2n1CCOc1ccccc1Cl +CCNC(=O)NC(C)c1ccc(N2CCOC2=O)cc1 +O=C(COc1ccc(F)cc1)Nc1ccc(-n2cnnn2)cc1 +CC(CNC(=O)C1COc2ccccc2O1)N(C)c1ccccc1 +CCN(CCc1ccccc1)C(=O)C(NC(C)=O)C(C)C +O=C(c1cccc(F)c1)N1CCN(c2nc3cccnc3s2)CC1 +Nc1ccc(C(=O)N2CCN(c3ncccn3)CC2)c(Cl)c1 +CCC(Sc1nnnn1C)c1ccc(F)cc1 +CC(Nc1oc(-c2ccco2)nc1C#N)c1ccccc1 +COc1cccc(CC(=O)Nc2ccc(C)cc2)c1 +CC(Oc1ccc(F)cc1Br)C(=O)Nc1nccs1 +CCCS(=O)(=O)NCc1ccc(NS(C)(=O)=O)cc1 +N#CC1CCCOc2c(Br)cccc21 +CC(NC(=O)C(C)(C)C)C(=O)N1CCC(C(=O)N(C)C)CC1 +CCCNC(=O)CNC(=O)Nc1ccc(C)c(-n2cnnn2)c1 +Cc1cccc(N2CCN(C(=O)c3cc(C4CC4)on3)CC2)c1 +CN(C)S(=O)(=O)c1ccc(Cl)c(N)c1Cl +Cc1ccc(CNC(=O)N2CCCCC2c2cn[nH]c2)cn1 +CC(=O)Nc1nnc(Cc2ccc(Cl)c(Cl)c2)s1 +CC(NC(=O)Nc1nccs1)c1ccccc1Cl +CC(CO)NC(=O)NCc1ccc2c(c1)OCO2 +COCCOc1ccccc1NC(=O)NC1CCCC1 +CCOC(=O)c1c(N)n(C2CC2)c2nc3ccccc3nc12 +CC1(C)Oc2ccc(NC(=O)N(CCO)C3CC3)cc2O1 +CC1CCCCN1C(=O)c1ccc(S(C)(=O)=O)cc1 +COC(=O)Cn1ccc(NC(=O)Nc2cccc(F)c2)n1 +Cc1nn(C)cc1CN(C)c1ncnc2[nH]cnc12 +COC(=O)c1ccc2c(=O)nc(-c3ccccn3)[nH]c2c1 +NS(=O)(=O)c1ccc2nc(Nc3ccccc3)sc2c1 +CSc1nc(C)cc(C(=O)Nc2cnn(C)c2)n1 +CN(C(=O)C1CN(S(C)(=O)=O)C1)C1CCCCC1 +CCc1cccc(C)c1NC(=O)CCNC(=O)C(C)(C)C +CC1(C)CCC(NC(=O)C2CCCCC2)(C(N)=O)CC1 +Cc1cccc(C(=O)NC(C)C(=O)NCc2cccc(C#N)c2)c1 +O=C(Nc1ccc(F)c(F)c1)N1CCN(Cc2cccs2)CC1 +Cc1c(C(C)NC(=O)CNC(=O)CC2CCCCC2)cnn1C +CCn1cc(C(=O)Nc2cc(Cl)c(N)c(Cl)c2)cn1 +CC(C)(C)c1ncc(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)s1 +CC(C)NC(=O)Cc1n[nH]c(-c2cncc(Br)c2)n1 +Cc1ccc(CNC(=O)CCC(=O)c2ccc3c(c2)CCCC3)n1C +CN(CC(=O)Nc1nncs1)c1c(F)cccc1F +CSc1ccc(C(=O)Nc2nnc(-c3cccnc3)o2)cc1 +CCn1nc(C(=O)Nc2nc3c(OC)cccc3s2)cc1C +O=C(CCn1nnc2ccccc2c1=O)Nc1cccc2ccccc12 +CN(Cc1c(F)cccc1Cl)C(=O)c1ccc2[nH]nnc2c1 +Cc1c(C(=O)OCc2ccccc2Cl)cnn1-c1ccncc1 +Cn1nnnc1SCCC(=O)NCc1ccccc1-n1ccnc1 +COc1ccc2cc(NC(=O)CCCNc3ncccn3)cnc2c1 +Cc1nc(C)c(C(=O)N2CC3CC=CCC3C2)s1 +CCOc1ccc(NC(=O)C(CC)CC)c(N)c1 +Cc1cc(C(=O)NCC(=O)Nc2ccccc2)c(C)n1C1CC1 +O=C(CCNC(=O)N(CCO)C1CC1)NC1CCCC1 +OCCc1cnn(CCOc2ccc3ccccc3c2)c1 +COCCCNc1nc(C(C)C)nc(OC)c1N +COc1ccc(NC(=O)c2ccc(Cl)cc2)cc1OC +COCCOc1ncccc1NC(=O)c1sc(C)nc1C +O=C(CCc1cccc(F)c1)NCCNC(=O)c1ccc(O)cc1 +C#CCOc1cc(F)ccc1NC(=O)C(C)Sc1ccccn1 +CC(C)n1nccc1-c1nnc(NC(=O)c2ccc(F)cc2)o1 +N#CCSc1nc(COc2ccc(Cl)cc2)n[nH]1 +COc1ccc(CC(=O)Nc2ccc(C(C)=O)cc2)cc1C +COc1ccc(OCCNC(=O)Cc2c(F)cccc2F)cc1 +Cc1ccc2cnn(CCC(=O)NCCN3CCOCC3)c2c1 +CC(c1ccc(Cl)cc1Cl)S(=O)(=O)c1nccn1C +CC(C)(C)OC(=O)N1CCCC2(CCN(Cc3ccccc3)C2=O)C1 +CCOc1ccc(C(=O)C(N)c2ccccc2)cc1 +O=C(CC(F)(F)F)Nc1ccnn1Cc1cnn(-c2ccccc2)c1 +Cc1ccc(C(C)NC(=O)CSc2nnc(C)n2N)cc1C +CC1CC(NC(=O)C(C)Oc2cccc(CO)c2)CC(C)O1 +Cc1cccc(N(CCCC(N)=O)S(C)(=O)=O)c1 +O=C(Cn1nc(-c2ccco2)n(C2CC2)c1=O)Nc1ccccc1F +O=C(Nc1nnc(-c2ccncc2)o1)c1c(F)cccc1F +CC(=O)c1cc2c(oc(=O)c3ccccc32)c(C)c1O +CC1CC(C)CN(C(=O)CNc2cccc(C(=O)N3CCCC3)c2)C1 +Cc1ccc(CS(=O)(=O)Nc2cnn(C3CCOCC3)c2)cc1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2cccc(C)n2)c1 +CN(C)c1ncccc1C(=O)NCC(=O)N1CCCc2ccccc21 +CC(=O)c1csc(COc2ccc(Cl)cc2C)n1 +CC(C)NC(=O)Cn1c(-c2nnc(C(C)C)o2)cc2ccccc21 +CC(NC(=O)CCC(=O)Nc1ccccc1F)C(=O)c1ccccc1 +Cn1cc(-c2nc(C(=O)OCCNc3cccnn3)cs2)cn1 +Cc1nnc(SCC(=O)Nc2ccc3c(c2)OCCO3)o1 +COc1ccc2c(=O)cc(C(=O)NCc3ccc(Cl)cc3)oc2c1 +O=C(NC1CCCN(c2ccccc2F)C1=O)C1CC=CCC1 +O=C1OCCN1CC(=O)N1CCCC1c1nc(-c2ccccc2)no1 +CCCCCN(C)C(=O)c1cc(Br)cn1C +Cc1n[nH]c(C)c1N1CCN(S(=O)(=O)C2CC2)CC1 +COc1cccc(C2(C#N)CCN(C(=O)OC(C)(C)C)CC2)c1 +CCn1cc(C#N)c(=O)n(Cc2cc(C(C)=O)ccc2OC)c1=O +CCn1nnc2c1C(COC)CN(C(=O)Cc1ccccn1)C2 +CC(C)C(=O)N1CCCC1C(=O)NCc1ncc(-c2ccccc2)o1 +COCC(=O)Nc1ccc2c(c1)N(C(=O)c1ccco1)CC2 +NC(=O)CCNC(=O)NCC1(c2ccc(Cl)cc2)CC1 +CCCCOc1ccccc1CNc1cnns1 +CC(=O)N1CCN(C(=O)c2ccc(OC(F)F)cc2)CC1 +COc1ccc(OC)c(S(=O)(=O)N2CCNC(=O)C2)c1 +CCC(CC)(CO)NC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +O=C1CCC2(CCOC2)CN1CCc1nc(-c2ccccc2)cs1 +Cc1csc(NC(=O)CCSc2nnnn2C)n1 +Cc1nn(C)cc1CCC(=O)Nc1cccc(-c2cn[nH]c2)c1 +COc1ccc(-c2ccc(-c3ccn[nH]3)cc2)nn1 +COc1cc(-c2noc(C(C)c3c(C)noc3C)n2)ccn1 +CCC(CC)C(O)CNC(=O)NCc1ccc2c(c1)OCCCO2 +CC(C)(C)C1CCc2sc(C(=O)N3CCC(C(N)=O)C3)cc2C1 +NC(=O)C1CN(C(=O)Nc2cc(C(F)(F)F)ccc2F)CCO1 +CCn1nnnc1-c1cccc(C(=O)N(C)Cc2ccccc2F)c1 +CCC(=O)N1CCCN(C(=O)c2cn[nH]c2)CC1 +CC(C)(C)c1ccc(NC(=O)CSc2nn3cnnc3o2)cc1 +CC(=O)NCCNC(=O)Cc1coc(-c2ccccc2)n1 +Cc1cc(CN(C)Cc2ccc(F)cc2C(F)(F)F)no1 +Cc1ccc(Cn2nccc2NC(=O)CN(C)c2ccccc2)o1 +CC(O)CNC(=O)Cn1nnc(-c2ccccc2)n1 +CCCCNC(=O)C(C)Oc1ccc(C)cc1CO +O=C(CCC(O)c1cccs1)NCc1ccccc1F +CC(C)c1nnc2n1CCN(C(=O)C1CC(=O)N(C3CC3)C1)C2 +Cc1nc(NC(=O)NCc2ccc(F)cc2)nn1C(C)C +O=C(c1ccsc1)N1Cc2ccccc2OC(c2ccccc2)C1 +CC(C)CNC(=O)C(C)Sc1nnc(CO)n1C1CC1 +Cc1sc(=O)n(CC(=O)N(C)CC(=O)NC(C)(C)C)c1C +Cc1csc(CCCNC(=O)Nc2ccccc2OC(F)F)n1 +Cn1c(CNC(=O)c2ccnc(OC3CCC3)c2)nc2ccccc21 +Cc1cccc(-n2nnc(C(=O)OC(C)C)c2C)c1 +CCC(=O)NCCNc1ccc(Nc2ccc(C)cn2)nn1 +Cc1nc(C(F)(F)F)ccc1C(=O)OCC1CCCO1 +CCN(C(=O)NCc1cnc(C)s1)C(C)c1ccc(F)cc1 +COc1ccc(Br)c(C(=O)Nc2cc(C)ns2)c1 +O=C(NCCCO)c1csc(-c2cc3ccccc3[nH]2)n1 +CS(=O)(=O)N(CC(=O)N1CCCCCC1)c1cccc(Cl)c1 +NC(=O)c1cccc(C(=O)NC(O)C(=O)c2ccc(F)cc2)n1 +O=C(CCC1CCCO1)OCC1COc2ccccc2O1 +O=C(c1cn(-c2ccccc2)nn1)N1CCSc2ccccc21 +CCN1CC(C(=O)Nc2ccc(OC)c3ncccc23)CC1=O +COc1ccnc(NC(=O)c2ccc(N3CCOCC3)c(F)c2)c1 +O=S1(=O)N=C(NCCc2nnc3n2CCCC3)c2ccccc21 +CC(C)(C)NC(=O)NCC1COC2(CCCCC2)O1 +O=C(NCCc1ccc(C(F)(F)F)cc1)c1ccoc1 +Cc1cccc(NC(=O)N(C)Cc2cc(C)no2)c1 +CCc1ccc(N2CC(C(=O)NCc3ccccc3F)CC2=O)cc1 +C=CCN(Cc1ccccc1)C(=O)c1nn(C)c2ccccc2c1=O +COC(=O)c1ncccc1OCc1coc(-c2c(F)cccc2F)n1 +CC(C)NC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +C#Cc1cccc(N(Cc2ccccc2)C(=O)CCOC)c1 +O=C(Nc1ccnn1C1CCCC1)c1ccc(F)cc1 +C=CCNC(=O)Cc1nnn(-c2ccccc2)c1C +CCOC(CCNC(=O)N1CC2CCC1C2)C(C)C +COCCOc1ccc(NC(=O)N2CCCC(CO)C2)cc1F +NC(c1ccc(S(N)(=O)=O)cc1F)C(F)(F)F +Cc1nc2nc(N)nn2c(C)c1CC(=O)Nc1ccc(F)c(Cl)c1 +O=C(CCC(=O)c1ccccc1)Nc1ccccc1F +CCC(C(=O)Nc1ccccc1F)n1c(C)cc(C)nc1=O +OC1CCN(c2cc(N3CC4C5CCC(CC5)C4C3)ncn2)CC1 +C=CCN1C(=O)C2(OCCO2)c2cc(Cl)ccc21 +C=CCc1ccc(OC2CNC(C(=O)OC)C2)c(OC)c1 +COc1ccc(C(=O)CNC(=O)c2cccnc2)cc1 +Cc1ccc(NC(=O)NC(CO)c2ccccc2)cc1S(C)(=O)=O +CCN(Cc1ccccc1Cl)C(=O)c1cn[nH]n1 +O=C(CCNC(=O)N1CCCC1c1ccccc1Cl)N1CCCC1 +O=C(Nc1ccccc1O)c1ccc(-c2ccco2)[nH]c1=O +COc1ccc(C(=O)Nc2ccn(Cc3ccccn3)n2)cc1OC +Fc1ccc(F)c(-n2nc(C(F)(F)F)c3c2CCNC3)c1 +CCOCCCNC1C(=O)Nc2cc(F)ccc21 +CNC(=O)c1ccc(NC(=O)C2(c3ccc(Cl)cc3)CC2)cc1 +CC1CCCCN1C(=O)CCCC(=O)N1CCCCC1C +COc1ccc(CC2(c3ccc(OC)cc3)NC(N)=NC2=O)cc1 +O=C(NCC1CCOC1)NC1CCc2ccccc21 +Nc1nc2c(c(-c3nc(N)nc4c3CCC4)n1)CCC2 +CCCNC(=O)c1ccc(NC(=O)C(C)CC)cc1Cl +CCCC(=O)N1CCC(Oc2nc3cc(OC)ccc3s2)CC1 +O=C(Nc1ccc(F)cc1)N1CCN(C(=O)c2ccccc2)CC1 +Cc1c(C(=O)C(C#N)c2ccccn2)oc2ccccc12 +CC(=O)N1c2ccccc2CC1C(=O)N(C)Cc1ccc(F)c(F)c1 +COc1ccc(CCNC(=O)c2cccn3c(=O)[nH]nc23)cc1 +COc1ccc(-c2cc(C(=O)NCCO)c(C)o2)cc1OC +CCc1ccc(-c2ccc(=O)[nH]n2)cc1S(=O)(=O)N1CCCC1 +C=CCn1c(SCC(=O)N2CCNC(=O)C2)nc2ccccc21 +Cc1ccc(S(=O)(=O)NCCC(O)C(C)(C)C)cc1 +Nc1c(Cl)ccnc1NCc1ccc(Cl)cc1 +O=C(Nc1ccccc1)c1cccc(-n2cccn2)c1F +Cc1ccc(NC(=O)CC2Sc3ccc(Cl)cc3NC2=O)nc1 +CCCc1nc(C(NC(=O)c2cc(C)oc2C)c2ccccc2)no1 +N#Cc1ccccc1CNCCc1ccc(F)cc1 +COC(=O)c1cccc(C(=O)OCC(=O)Nc2cccc(F)c2)c1 +COc1cc(-c2noc(-c3ccc(F)c(C)c3)n2)ccn1 +O=C(Nc1ccc(F)c(Cl)c1)c1cccs1 +CCOC(=O)C1C(=O)CC2CN(C(=O)OC(C)(C)C)CC1N2C +O=C(Nc1nnc(-c2ccsc2)o1)c1ccc(F)cc1F +c1ccc(COCCNc2ncnc3c2cnn3-c2ncccn2)cc1 +CCOC(=O)CS(=O)(=O)c1ccc(C(F)(F)F)cn1 +O=C(NCC1CC1)NC(c1cccnc1)c1cccc(C(F)(F)F)c1 +CC(=O)Nc1nc(C)c(S(=O)(=O)N(C)C)s1 +COc1ccccc1NC(=O)N(C)CCc1c(C)nn(C)c1C +CC(O)(CNC(=O)NC1CCCCC1)c1cccs1 +Cc1csc(C(C#N)C(=O)C(Oc2ccccc2)c2ccccc2)n1 +COc1cccc2c1OCC(C(=O)N1CC3C4CCC(O4)C3C1)C2 +Cc1ccc(C)c(N(C(=O)c2nc3nccc(C)n3n2)C(C)C)c1 +Cc1cccc(NC(=O)NC2CCOC(C)(C)C2)n1 +Cn1c(SCCCOc2ccc3c(c2)OCO3)nnc1C1CC1 +CCC(=O)Nc1nnc(SCC(=O)c2ccc(C)cc2)s1 +CCOC(=O)c1cnn(-c2ccc(Cl)cc2)c1O +COc1cccc2sc(NC(=O)C3CCN(C(C)=O)CC3)nc12 +COC(=O)CN1CCOC(c2ccc3cc(OC)ccc3c2)C1 +CCNC(=O)Cc1cc(=O)oc2cc(OC)ccc12 +COc1ccc(NC(=O)Nc2cc(C)ccn2)c(OC)c1 +COC(=O)c1ccc(N(C(=O)Cn2cccn2)C(C)C)c(C)c1 +Cc1csc(CNC(=O)CCN2C(=O)C(C)Oc3ccccc32)n1 +COC(C)c1cccc(NC(=O)NCc2ccc(S(C)=O)cc2)c1 +CC(O)CN1CCN(C(=O)C2Cc3ccccc3S2)CC1 +CC(c1ccc(Cl)cc1)N(C)C(=O)NCc1ncn(C)n1 +COCCCN(CC(=O)N1CCNCC1)C(=O)c1ccc(C#N)cc1 +Cc1cccc(CC2Oc3cc(O)ccc3NC2=O)c1C +Cc1cccc(OC(C)CNC(=O)NCc2ncn(C)n2)c1 +CCOc1ccc(CC(=O)N2CCOc3ccccc32)cc1 +Cc1nn(C)c(C)c1OC(=O)c1ccc(OCC(F)F)nc1 +CN(Cc1cc(-c2ccccc2)on1)S(=O)(=O)c1ccc(F)cc1 +N#Cc1cccc(NS(=O)(=O)c2ccccc2C(F)(F)F)c1 +CCCS(=O)(=O)N(Cc1cccc(Cl)c1)C(C)C +Cn1ccc(C(=O)OCC(=O)NC2CCCCC2)n1 +Cc1ccnc2nc(C(=O)NC3(c4ccccc4)CCCCC3)nn12 +CC(C)C(C)NC(=O)CS(=O)(=O)c1nnc(N2CCCC2)s1 +Cc1nc(CNc2ccccc2OCC(=O)N2CCOCC2)no1 +Cc1ccc(-n2nnnc2N(C)CC(=O)N(C)C)cc1 +Cc1nn(-c2ccc(F)c(Cl)c2)c(=O)c2c(C)noc12 +COc1cc2c(cc1OC)CCN(C(=O)C(C)(C)C#N)CC2 +Cc1c(C(=O)OCc2nc(N)nc(N(C)C)n2)oc2ccccc12 +Nc1cc(Cl)cnc1NCc1ccccc1Cl +O=C(NCCCO)c1ccc(-c2ccc(F)c(Cl)c2)o1 +CNCC(=O)OCc1ccc2c(c1)N(C)C(=O)CO2 +O=C(c1ccc2[nH]ccc2c1)N1CCC2CCCCC21 +CCC(C)C(=O)NCc1ccc(-n2cncn2)nc1 +COCCOc1ccccc1C(=O)OC1CCCC1 +O=C(Nc1ccc(N2CCCCC2)cn1)c1cc(-c2ccncc2)on1 +CC(C)(C)n1cc(C(=O)N2CCCN(c3cccnn3)CC2)cn1 +Cc1noc(C)c1CN1C(=O)C(C)Oc2ccc(O)cc21 +O=C(CCNS(=O)(=O)c1ccccc1F)Nc1cccc(F)c1 +Cc1cccc(C(=O)NCC#CCOc2ccccc2C(N)=O)c1 +CCN(C1CCN(Cc2ccc(F)cc2C#N)CC1)S(C)(=O)=O +COc1ccc(C(=O)Cn2nc(C(F)(F)F)n(C)c2=O)cc1 +Cc1cc2ccccc2n1CC(=O)Nc1nccs1 +CC(=O)N1CCc2ccc(NC(=O)Nc3cc(C)cc(C)c3)cc21 +O=C(NCCCN1CCCC1=O)c1ccc(Cn2ccccc2=O)o1 +Cc1cc(C(C)NC(=O)Nc2ccccc2Cn2cccn2)c(C)o1 +CCC(=O)Nc1cccc(C(=O)NC(C)(C)c2nc(C)c(C)s2)c1 +O=C(Cc1ccc[nH]1)Nc1ccc(-n2cncn2)c(C(F)(F)F)c1 +CCOc1ccc(C2C(C(=O)OC)=C(C)Nc3ncnn32)cc1 +C=CCC1CCC(=O)N1CCc1ccc(OC)cc1 +O=C(Cc1c[nH]c2ccccc12)NCc1ncc(-c2ccccc2)o1 +CC(=O)c1cccc(S(=O)(=O)Nc2cccc(Cl)c2F)c1 +CCc1nc2cc(C(F)(F)F)ccc2n1CC1CCCO1 +CC(C)n1cc(Br)cc1C(=O)NC(C(N)=O)C(C)(C)C +O=c1[nH]nc(SCc2coc(-c3ccccc3)n2)n1C1CC1 +COCCCN(C)C(=O)Nc1ccc(C)c(NC(C)=O)c1 +CC(C)(C(=O)Nc1ncc(C(N)=O)s1)c1ccccc1 +CN(Cc1ccco1)S(=O)(=O)c1ccc(Cl)cc1 +COc1ccccc1C1CC1NC(=O)Nc1cccc(-c2cnco2)c1 +Cc1csc(C(C)NC(=O)c2ccnc(OC3CCC3)c2)n1 +CC(=O)Nc1ccc(-c2csc(Nc3cc(C)ccn3)n2)cc1 +CCC(NS(=O)(=O)Cc1ccon1)c1ccc(OC)cc1 +O=C(Cn1ncc2c([nH]c3ccccc32)c1=O)N1CCCCCC1 +CC(C)NC(=O)Cn1ccc2ccc(Cl)cc21 +COCCOCCC(=O)Nc1c2c(nn1C)CCC2 +CCCn1nccc1NC(=O)CNC(=O)c1ccoc1C +CC(CNC(=O)NCc1cccc(C#N)c1)c1nccs1 +N#Cc1ccccc1C(N)c1nnc(-c2cccnc2)o1 +COc1c(CN2CCc3cccc(F)c3C2)c(C)nn1C +COc1ccccc1CC(=O)c1cccc(F)c1F +COC(C(=O)Nc1cnn(CC(=O)N(C)C)c1)c1ccccc1 +Cc1ccc2nc(SCC(=O)NC(C)C(C)C)[nH]c2c1 +COc1ccc(-c2nc3cc(N)ccc3o2)cc1Cl +COC(=O)CCNC(=O)c1nn(C(C)C)c(=O)c2ccccc12 +CCCCNC(=O)C1CCN(C(=O)CC(C)C)CC1 +Cn1ccnc1Cn1c(C(F)(F)F)nc2cc(O)ccc21 +Fc1cccc(NCc2cc(Br)cs2)n1 +Cc1ncc(CNC(=O)CN(C)S(=O)(=O)c2ccccc2)s1 +O=C(c1ccccc1)N1CCN=C1c1ccccc1 +CC(C)CNC(=O)N1CCCC(C(=O)N(C)CC(F)F)C1 +CCCCC(NC(N)=O)C(=O)Nc1nc(C)cs1 +CCc1ccc(NC(=O)Cn2cc(C(F)(F)F)ccc2=O)cc1 +Cc1ncc(CNc2c(F)cc(F)cc2Br)s1 +COC1(CNC(=O)c2cnc3ccc(C)cn23)CCOCC1 +Cc1cc(C)n2nc(NC(=O)c3cccnc3)nc2n1 +Cc1cccc(NC(=O)CN(C)C(=O)c2ccccc2)c1C(N)=O +COc1ccccc1C(=O)CNC(=O)Cc1ccc(F)cc1 +Cc1n[nH]c(SCC(=O)NCCc2ccccc2)nc1=O +COc1cc(COc2ccc(C)nc2)ccc1SC +CCc1nn(-c2ccccc2)c(NC(=O)C(CC)n2cccn2)c1C +CCNC(=O)C(C)NC(=O)c1ccc2c3c(cccc13)CC2 +CC(CC(=O)c1cccs1)NC(=O)C1CCC(C)O1 +CSc1ccc(C(=O)NCc2c[nH]nc2C)cc1 +CCCn1cc(C(=O)NCCCO)c(=O)c2c(N)cccc21 +Cc1ccc(C)c(C(=O)NCc2cccc(-c3n[nH]c(C)n3)c2)c1 +Cn1cc(C(=O)N2CCN(c3cccc(O)c3)CC2)c(C(C)(C)C)n1 +O=C(NCc1ccc(F)cc1)C(O)(c1ccccc1)c1ccccc1 +c1cncc(-c2n[nH]cc2CNCc2cccnc2OC2CCCC2)c1 +CCOc1cccc(CC(=O)Nc2cc(F)ccc2OC)c1 +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)CCCC(=O)N(C)C +CC(=O)c1ccc2c(c1)N(CC(=O)OC(C)C)C(=O)CO2 +Nc1cc(N)nc(SCC(=O)c2ccc(Cl)c(Cl)c2)n1 +CC(=O)Nc1nc(C(=O)NCCc2ccsc2)cs1 +CC(C)c1nc(CC(=O)N2CCc3sccc3C2)cs1 +Cc1cc(C)n2nc(C)c(C(=O)OC(C)COc3ccccc3)c2n1 +CCN1CC2CCN(c3ncccn3)CCC2S1(=O)=O +Cc1c(CNC(=O)CCC2CCCO2)oc2ccccc12 +CCc1cc(C2CCCN2C(=O)Cc2ccc(OC)c(OC)c2)on1 +COC(=O)N1CC2C(CN3CCN(S(=O)(=O)N(C)C)CC3)C2C1 +Cc1csc(NC(=O)N(C)Cc2cnn(-c3ccccc3)c2)n1 +COC(=O)c1cc(C)nc2c1c(C)nn2CC(F)F +COc1ccc(C(C)NC(=O)c2ccccc2)cc1OC +Cc1nn(C(C)C)c(C)c1NC(=O)Nc1cccc2[nH]ccc12 +Cc1nc(C)c2c(C)c(C(=O)OC3CCCC3)sc2n1 +C=CCNC(=O)Nc1ccccc1Cc1nc(-c2ccco2)no1 +Cc1cc(C)nc(SCC(=O)N2CCCCCC2)n1 +CCN1C(=O)C(=O)c2cc(Br)cc(Cl)c21 +CCSc1ccc(C(=O)c2cccc(N)c2)cc1 +CCNC(=O)c1csc(N2CCCC(C)C2)n1 +CN(Cc1ccncc1)C(=O)Nc1ccc(F)c(F)c1F +CC1CN(CCC2CCN(CC(F)(F)F)CC2)CC(C)O1 +Cc1csc(S(=O)(=O)Cc2nc(N)nc(N(C)C)n2)n1 +COCCNc1nc(-c2ccco2)nc2ccccc12 +CCc1n[nH]c(SCc2csc(-c3cnn(C)c3)n2)n1 +COC(C)(C)CC(C)NS(=O)(=O)c1cccc(F)c1C#N +Cc1c(C(=O)N2CCCCC2)sc2nc3n(c(=O)c12)CCCCC3 +NC(=O)C1CCC(C(=O)OCC2CC2(Cl)Cl)CC1 +CNc1nc(C)ccc1C(=O)OCC(=O)N(c1ccccc1)C(C)C +C#CCNC(=O)c1cccc(S(=O)(=O)NCc2ccccc2)c1 +CC(C)NC(=O)COc1coc(CN2CCc3ccccc32)cc1=O +NC(=O)C1CCN(C(=O)COc2ccc(Br)cc2)C1 +Cc1nn(C)c(C)c1S(=O)(=O)NC(C)C1CC1 +Cc1ccc(S(=O)(=O)NCCCn2nc(C)cc2C)cc1 +CCc1nc(COc2ccc(C)cc2S(=O)(=O)N(C)C)cs1 +COc1cccc(Nc2ncnc(-n3ccnc3)c2N)c1 +Cc1cc(NC(=O)c2[nH]nc(-c3ccccc3)c2Br)[nH]n1 +O=C(CCn1ncc(=O)c2ccccc21)NCC1CC1 +Cc1cccnc1NC(=O)Nc1cnn(Cc2cn3ccccc3n2)c1 +NC(=O)c1cc(S(=O)(=O)NCC2CCCO2)cs1 +CC(C)Oc1cccc(CC(=O)N2CCN(C(=O)N(C)C)CC2)c1 +Cc1ccc(CNc2nc3c(c(=O)[nH]c(=O)n3C)n2CCO)cc1 +COC(=O)c1c(OC)cc(C)c(Br)c1C +COc1ccccc1CCNC(=O)C1CCN(C(C)=O)CC1 +Cc1n[nH]c(C)c1CCNS(=O)(=O)NCc1ccccc1 +CCNC(=O)CC(C#N)c1cc(OC)c(C)cc1OC +Cc1cccc(CN(C(=O)c2c(C)c(C)nn(C)c2=O)C2CC2)c1 +Cc1ccnc(Nc2ncnc(-n3nc(C)cc3C)c2N)c1 +COc1ccc(C2(c3nnc(-c4ccccc4)o3)CCOCC2)cc1 +O=C(NCc1ccsc1)C1CCC(C(F)(F)F)NC1=O +CCc1ccc(OS(=O)(=O)c2ccc(OC)c(OC)c2)cc1 +O=C(NCC1(c2ccccc2)CC1)C1Cc2ccccc2O1 +Cc1ccn2c(=NC(=O)c3cc4cc(F)ccc4[nH]3)[nH]nc2c1 +CCc1onc(C)c1NC(=O)Nc1cc(OC)cc(OC)c1 +Cc1ccc(CN(C)C(=O)CCCNC(=O)c2ccccc2)o1 +CN(CC1CCN(c2ccccc2)C1)c1ccncn1 +Cc1ccn(-c2ccccc2NCc2cnn(-c3ccccc3)n2)n1 +Cc1ccccc1NC(=O)COc1ccc2c(c1)OCO2 +O=C(Oc1cccc(-n2cnnn2)c1)c1ccccc1F +NS(=O)(=O)c1ccc(CNC(=O)c2ccc3ccccc3c2)cc1 +Cc1ccc(CN(C)C(=O)c2ccc(-c3ccco3)nc2C)s1 +CCn1ncc(-c2cc(C)c(OC)c(C)c2)c(CC#N)c1=O +Cc1c(C)n(CCO)c2ncn3nc(COc4ccccc4)nc3c12 +CCOC(=O)c1ccccc1CC(=O)c1ccccc1 +CC(NC(=O)C1CCCC1)c1ccc(F)cc1F +O=C(CCC(O)c1ccc2c(c1)OCCO2)N1CCCCC1 +O=C(NCCc1ccccn1)C1COC(=O)N1Cc1cccnc1 +O=c1[nH]c(NCc2ccco2)nc2nccc(-c3ccsc3)c12 +COc1ccc(C(=O)Nc2ccccc2F)c(O)c1 +CCOC(=O)CCc1ccc(Br)cc1F +CCCN(CC(F)F)C(=O)Nc1cccc(-c2nnnn2C)c1 +CC(C)(C)C(=O)C(c1ccncc1)n1nnc2ccccc21 +CC(C)(C)Oc1ccnc(C(N)=O)c1OC1CC1 +O=C(CCOc1ccccc1F)NCc1ccccc1 +Cc1ccc(C)c(SC(C)C(=O)N2CCC(C(N)=O)CC2)c1 +COc1ccc(CNCC(O)c2cccc(C(F)(F)F)c2)cc1 +Nc1nc(SCC(=O)c2ccc3c(c2)OCO3)n[nH]1 +CCn1c(C)cc(C(=O)NCCCn2c(C)nc3ccccc32)c1C +COC(=O)c1ccccc1-n1c(=O)c2ccccc2n(CC#N)c1=O +Cc1nc2ncccc2c(=O)n1CCNC(=O)c1ccccc1F +CC(C)c1nn(C)cc1C(=O)N1CCC(c2ccccc2)CC1 +CC(C)(C)OC(=O)CCn1cnc2sc3c(c2c1=O)CCCC3 +COCCC1(O)CCN(c2nc3c(cc2C#N)CCCC3)CC1C +O=C(Nc1nncs1)c1ccc(-c2cccs2)[nH]c1=O +C#CCN(C(=O)c1cccc2cn[nH]c12)C1CCCCC1 +CC(C)(C)OC(=O)n1c(C#N)cc2c(O)cccc21 +Cc1ccc2ncc(C(=O)Nc3cc(C)nn3C)n2c1 +CC(=O)c1c(C)[nH]c(C(=O)OC(C)C(=O)Nc2ccc(F)cc2)c1C +CC(=O)N1CCN(C(=O)c2nc(-c3cccs3)oc2C)CC1 +CCOc1cccc(C(=O)Nc2cncnc2N(C)C)c1 +CCc1onc(C)c1NC(=O)C(C)(C)C1CCCC1 +COc1ccc(-c2csc3nc(N)cn23)c(Cl)c1 +CCOC(=O)CCNC(=O)N1CCCC1c1ccc(OC)cc1 +NC(=O)C(NC(=O)c1cc(C2CC2)on1)c1ccccc1 +COC(=O)CNC(=O)c1cccnc1Oc1ccc(Cl)cc1 +O=C(c1c[nH]c2ccccc2c1=O)N1CCCC1c1ccc[nH]1 +CC(C#N)(NC(=O)CN1CCN(c2ccccc2F)CC1)C1CC1 +CN(CCc1ccccc1)C(=O)Cc1csc(-c2ccccn2)n1 +Cc1ccc(S(=O)(=O)N2CCC(=O)C2)cc1C +O=C(Cn1nnc(-c2cccc(C(F)(F)F)c2)n1)N1CCCCC1 +COC(=O)CC(C)NC(=O)c1nc(N2CCCC2)ncc1Cl +Cc1nc(C(NC(=O)Nc2nncs2)c2ccccc2F)no1 +CCc1nc(SCC(=O)Nc2nc(C)c(C)s2)[nH]c(=O)c1C +Cc1nc(COc2ccc(C(=O)NC3CCCCNC3=O)cc2)no1 +CC1CCN(C(=O)Nc2ccc(OCC(F)(F)F)c(C#N)c2)CC1 +O=C(NC1CCc2[nH]ncc2C1)N1CCc2ccc(Cl)cc2C1 +O=C(Nc1cccc2c1NCCC2)C1CCCOC1 +CC(C)NC(=O)CSc1ccccc1C(=O)N1CCC1 +CN(C)C(=O)CN(C)S(=O)(=O)c1cnn(-c2ccccc2)c1 +Cc1ccc(Nc2n[nH]c(N)c2S(=O)(=O)c2ccccc2)cc1 +COCCNC(=O)Cn1nc(C#N)cc1-c1ccco1 +CCN(CC)S(=O)(=O)Nc1ccc(C)c(O)c1C +O=C(Nc1nc(CC(=O)N2CCCCC2)cs1)NC1CCCC1 +CC(=O)N1CCN(C(=O)c2ccccc2NC(=O)C(C)(C)C)CC1 +COc1ccc(OC)c(Nc2ncnc(N3CCCC3)c2N)c1 +Cc1nc(COc2ccc3ncccc3c2)sc1CO +Cc1cccc(OCCN(C)Cc2nn3c(=O)cc(C)nc3s2)c1 +CCN(Cc1ccc2c(c1)CC(C)(C)O2)CC(C)C#N +CC(Sc1nnnn1C1CC1)C(=O)OC1CCCCC1 +O=C(Nc1ccc2c(c1)N(C(=O)C1CCCC1)CC2)C1CCC1 +Cc1cnn(CC2CCCN2C(=O)C(C)n2ccnc2)c1 +CCc1cnc(C)nc1NCC1CCN(c2cnn(C)c(=O)c2)CC1 +CCCc1nc2cc(Cl)cnc2n1CCCC#N +Nc1ccc(SCc2noc(C3CC3)n2)c(F)c1 +CC(=O)Nc1cc(NC(=O)Cc2ccc(F)c(F)c2)ccc1C +CCOCC1CCC2C(CCN2C(=O)Cc2ccccc2)O1 +Cc1nc(Cc2noc(CCn3cnc4sccc4c3=O)n2)no1 +O=C(COc1ccc(Cl)cc1Cl)N(CCO)CCO +Cc1cnc(NC(=O)CN2C(=O)CSc3ccccc32)s1 +CC(=O)N1CCN(C(=O)NCC2COc3ccccc3O2)CC1 +CCC(OC(=O)c1ccc(=O)n(C)n1)C(C)(C)c1ccccc1 +CCOc1ccc(N(C)C(=O)c2cc(-c3cccnc3)[nH]n2)cc1 +CC(C)(C)n1nccc1NC(=O)CCc1nc(-c2ccccn2)no1 +CCN(CC(C)C#N)C(=O)C1CCN(S(C)(=O)=O)CC1 +O=C(c1cc2ccccc2s1)N1CCN(Cc2ccsc2)CC1 +O=c1[nH]c(NC2CCCCC2O)nc2ccccc12 +Cn1cc(-c2nn3c(Cc4ccc(F)cc4)nnc3s2)cn1 +CCCCNC(=O)CNc1ccc(C(=O)N2CC(C)OC(C)C2)cc1 +COc1nccnc1N1CCC(N(C)C(=O)c2ccoc2)C1 +COc1cccc(C(N)=O)c1OCc1cccc(Cl)c1 +COC1(C)CC(NC(=O)CCc2ccccn2)C1(C)C +Cc1ccc(C(=O)NCCNC(=O)NCc2cccnc2)cc1 +CC=Cc1ccc(OCC(=O)NCc2nc(C)sc2C)c(OC)c1 +Nc1ccc(NC(=O)c2cncc(Br)c2)cn1 +Cn1cc(C(N)=O)cc1C(=O)NCCc1cccs1 +CC(=O)Nc1cccc(C(=O)OCC(=O)c2ccccc2)c1 +CC(=O)NCCCNC(=O)N(C)CCc1ccccc1 +O=C(CCc1ccncc1)N1CCCN(c2ccc(F)cc2)CC1 +Cc1ccc(C(=O)NC2CC3CCC2C3)cc1NS(C)(=O)=O +COc1cc(CNc2cccc(SC)c2)ccc1O +COC(=O)C1CCN(C(=O)Cc2ccccc2Cl)c2ccccc21 +Cc1cnc(CCNC(=O)CCc2nc3ccccc3c(=O)[nH]2)s1 +O=S(=O)(NCCCn1cccn1)N1CCCC1c1ccco1 +O=C(NCCS(=O)(=O)c1ccc(F)cc1)c1cnc(C2CC2)nc1 +CC(C)(C)NC(=O)CNc1ccc(C(=O)N2CCOCC2)cc1 +C#CCNC(=O)NCCCOc1ccc(OC)cc1 +Clc1ccc(CNc2cnccn2)c(Cl)c1 +CC(=O)N1CCC(Nc2nc(C(F)(F)F)nc3ccccc23)CC1 +Cc1noc(C(C)N2CCN(C(=O)c3ccccc3F)CC2)n1 +Cc1ccc(C(=O)NC(C#N)C2CCCCC2)s1 +O=C(NCCc1c(Cl)cccc1Cl)c1ccc[nH]c1=O +O=C(NCCC(F)(F)F)c1n[nH]c2ccccc12 +COc1ccc(Cl)cc1C(C)C(C#N)N(C)C +Cc1occc1C(=O)N1CCC2(CC(=O)N(c3cnn(C)c3)C2)C1 +Cc1ccccc1CNC(=O)C1CC(=O)N(CCc2ccccc2)C1 +CCc1nnc2n1CCN(C(=O)C1CC1c1ccc(OC)cc1)C2 +CC(C)(C)c1cc(C(=O)NCc2nncn2-c2ccccc2)[nH]n1 +CCCOc1ccc(CNC(=O)C2CC3CCC2O3)cc1OC +N#Cc1ccc(NC(=O)c2cc(Cl)cc(Cl)c2)nc1 +CCn1c(SCc2ccc(F)c(F)c2)nnc1-c1ccncc1 +CCn1cc(S(=O)(=O)N(c2ccc(OC)cc2)C(C)C2CC2)cn1 +CCN(CCO)C(=O)CCc1ccc(C(C)(C)C)cc1 +COC(=O)Cn1cnc2scc(-c3ccc(OC)cc3)c2c1=O +CC(NC(=O)c1ccc(NC(N)=O)cc1)c1ccc(F)c(F)c1 +CCOc1ccc(C(=O)NCc2ccc(C(=O)NC)cc2)cc1OC +C=CCn1c(SCC(=O)OC)nnc1-c1ccc(F)cc1 +Cc1ccccc1NC(=O)N1CCOC2(CCOCC2)C1 +O=C(Nc1ccn(Cc2ccc(Cl)cc2)n1)C1CCCO1 +COc1cccc(COC(=O)c2ccc(N3CCC(O)CC3)cc2)c1 +O=C(NCc1ccncc1)c1ccc2cnsc2c1 +CC(C)CC(C)NC(=O)c1cccc(Nc2cnccn2)c1 +COc1ccccc1NC(=O)NC(c1ccccc1)c1ccncc1 +Cc1ccccc1NC(=O)Cc1ccc2c(c1)OCO2 +CN(C)c1nc(N)nc(Cn2ccc(-c3cccs3)n2)n1 +COc1cc(OC)c(CCNC(=O)c2ccc(C#N)cc2)c(OC)c1 +CNC(=O)COC(=O)c1ccc(-n2cccn2)cc1 +Cc1occc1CN(C)c1ncnc2sccc12 +CCOC(=O)C1CCN(C(=O)c2cccc(C)c2C)CC1 +Nc1cccc2c1CCN(C(=O)CCOc1ccccc1)C2 +Cc1cc(C)c(NC(=O)CSc2ncccn2)c(C)c1 +CCOC(=O)CN(C(=O)c1oc2ccccc2c1C)C1CC1 +Nc1nnc(SCCOc2ccccc2F)n1C1CC1 +O=C(Nc1ccc(C(=O)N2CCCC2)cc1)c1cc2ccoc2s1 +CN(CC(=O)NC1(C)Cc2ccccc2C1)C(=O)c1cccs1 +CC(Oc1ccccc1)C(=O)OCc1nc2ccccc2[nH]1 +COc1cc(C(=O)NCCNC(C)=O)ccc1OC(C)C +Cc1cnc(N2CCCC3(CC(Nc4cccnc4)CO3)C2)nc1 +O=C(CC1CC2CCC1C2)N1CCC(OCc2ccccc2F)CC1 +CC(C(=O)NCc1ccc(Cl)cc1)N1CCn2c(nn(C)c2=O)C1 +COCCn1nc(C(=O)NC(C)c2ccc(C)c(F)c2)ccc1=O +CCCS(=O)(=O)NCc1cc(Cl)ccc1OC +CC(Sc1nnc(Cc2cccs2)n1C1CC1)C(=O)NC1CC1 +COCC(=O)N1CCC2(CC1)CC(Nc1cccc(OC)c1)CO2 +Cc1nc(C(=O)NCC2CCOC2)nn1-c1ccc(F)cc1 +CCCCCSc1nc2c([nH]1)c(=O)n(C)c(=O)n2C +CC(=O)c1ccccc1NCc1cnn2ccccc12 +CCN(C(=O)c1ccc(C(=O)OC)s1)C1CCCC1 +CC(=O)NC(C)(C)c1noc(Cc2ccc(F)c(F)c2)n1 +CS(=O)c1ccc(C(=O)NCCc2ccccc2)cc1 +Cc1c(N)cccc1-c1nn2c(C(F)(F)F)nnc2s1 +CCCn1c(SCC(=O)c2ccc(C)cc2C)n[nH]c1=O +CCOC(=O)CN(CC)C(=O)c1cnc2ncnn2c1C +O=C(CCNC(=O)c1ccc2c(c1)CCC2)NCc1cccnc1 +COc1ccc(-c2ccc(CCC(=O)Nc3ncccc3O)o2)cc1 +COC(=O)c1c(NC(C)=O)sc(C(=O)Nc2cccc(C)c2)c1C +O=C(Nc1cccc(Cl)c1)Nc1nccn(-c2ccccc2)c1=O +CCOC(=O)c1c(C)nc2sc3c(c2c1N)CCCC3 +COC(=O)C(C)CN(C)C(=O)c1cnc(C2CCCO2)s1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(C)cc3cccnc23)c1C +NC(=O)N1CCCC(C(=O)NCCNC(=O)c2ccc(F)cc2)C1 +COc1ccc(C(=O)N(CC(=O)Nc2ccc(F)cc2)C(C)C)cc1 +CCCCN(CC(N)=O)C(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +Cc1ccc(S(=O)(=O)NCCC(O)c2ccco2)c(C)c1 +CC(=O)Nc1ccc(C)c(NCc2ccc(-n3nc(C)cc3C)cc2)c1 +Cc1c(Br)cccc1C(=O)NC(C)(C)CO +O=C(CCn1[nH]c(=O)ccc1=O)Nc1ccc2c(c1)CCC2 +CC(=O)N1Cc2ccccc2CC1C(=O)N1CCC(C(N)=O)CC1 +COCc1ccc(C(=O)NC(C)c2ccc(C)o2)o1 +CCN(CCc1ccccc1)C(=O)Nc1ncc(C)s1 +CC(C)n1nc(O)c2c1NC(=O)CC2c1ccc(F)cc1F +Cc1c(Sc2nnnn2C(C)(C)C)c(=O)[nH]c2ccccc12 +CC(Sc1nncn1C1CC1)C(=O)C12CC3CC(CC(C3)C1)C2 +CCN(Cc1c(F)cccc1F)C(=O)NC1CCC(O)CC1 +O=C(Nc1c[nH]ccc1=O)c1cccc(-n2cnnn2)c1 +O=C(Cc1ccc2c(c1)OCCCO2)c1c(O)cc(O)cc1O +COC1C2CCC1CN(C(=O)Nc1ccc(-n3cccn3)cc1)C2 +CCOc1ccc(-c2ccc(CC#N)c(=O)n2C)cc1 +Cc1c(C(=O)NCc2ccccc2)nnn1-c1cccc(Cl)c1 +N#Cc1cccnc1N1CCC(NC(=O)c2cccnc2)CC1 +CCOc1ccc(C(=O)NCc2ccccc2OC)cc1 +O=C(Cn1nc(-c2ccco2)ccc1=O)c1ccc2c(c1)OCCO2 +Cc1nn(-c2ccccc2)nc1C(=O)NCC(=O)NCc1ccco1 +CCC(CC)C(=O)c1ccc(OCCO)c(N)c1 +CC(C)Cc1nnc(NC(=O)NCc2cnn(C)c2)s1 +CCCOc1ccc(C(=O)Nc2cccc(C(C)=O)c2)cc1OC +CCOc1ccc(S(=O)(=O)Nc2ccc3oc(=O)[nH]c3c2)cc1 +O=C(NCCOc1ccccc1)NCCc1nnc2n1CCCCC2 +CCCC(=O)N1CCCCC1C(=O)Nc1ccc(F)c(NC(C)=O)c1 +C#CCOC(=O)C(CC)Sc1ccc(C(C)=O)cc1 +CC1Oc2ccc(NC(=O)NCCc3ccccn3)cc2NC1=O +COc1ccccc1C(=O)NCCOc1ccc2c(c1)OCO2 +CC(=O)c1ccc(C(=O)N(C)CCCOc2ccc(F)cc2)cc1 +OCc1nnn(CCCc2ccccc2)c1-c1cccnc1 +Cc1c(CN2CCCCC2CC(N)=O)c(=O)n(-c2ccccc2)n1C +CN1CCC(NC(=O)c2c(O)cc(F)cc2F)=NC1=O +O=C(Nc1cc2c3c(c1)CCN3C(=O)CC2)c1ccccc1F +CC1CC(=O)Nc2cc(S(=O)(=O)NCCO)ccc2O1 +O=C(CCCNC(=O)C1CC1)Nc1ccc2[nH]c(C3CCC3)nc2c1 +CCOC(=O)C1(NC(=O)c2cncc(-c3cnn(C)c3)c2)CCCC1 +COc1ccc(S(=O)(=O)N2CCCCC2)c(Cl)c1Cl +CC(NC(=O)NCc1ccc(F)c(Cl)c1)C(=O)N1CCCCC1 +COc1cc(CNc2ncc(C)s2)cc(OC)c1 +CCN(CC)C(=O)N1CC(C)(C)NCC1c1ccccc1 +COc1ccc(C(=O)Nc2ccccc2-n2cncn2)c(F)c1 +CCOC(=O)C1(O)CCN(C(=O)Cn2cc(C)c3ccccc32)CC1 +CCC1COCCN1C(=O)Cc1c[nH]c2c(C)cccc12 +CNC(=O)c1ccc2c(c1)nnn2Cc1cccc(OC)c1 +Cc1cc(OCC(=O)Nc2ccc(C(F)(F)F)cc2)nnc1C +CCN(CC)c1nc2ccccc2n2c(C)nnc12 +CC(=O)Nc1ccc(-c2nc3c(C)cc(NC(C)=O)cc3[nH]2)cc1 +O=S(=O)(NCCCOc1ccccc1F)N1CCOCC1 +CC(NC(=O)NCC1(c2ccccc2)CC1)c1ccc2c(c1)CC(=O)N2 +Cc1ccc(CNC(=O)Nc2n[nH]c(-c3ccccc3F)n2)s1 +Cc1ccccc1CNc1ccc2[nH]nc(C(N)=O)c2c1 +CC=CCOC(=O)c1cc(OC)c2c(c1)OCCO2 +Cc1ccc(C(N)=O)cc1NC(=O)CCNS(C)(=O)=O +Cc1nc(C(=O)NCC(O)c2ccccc2)cs1 +CCCC1CN(C(=O)CCC2CCCO2)CCO1 +NC(=O)c1ccc(OCC(=O)N2CCc3ccc(F)cc32)cc1 +COC(=O)C(Cc1ccc(O)cc1)NC(=O)Cc1ccccc1 +COc1ccccc1Oc1ncnc(Oc2ccccc2)c1N +CCC(CNC(=O)NC(C)CO)Cc1cccc(Br)c1 +COc1cc(N)cnc1NCCCN1CCOCC1 +N#Cc1ncn(Cc2ccc(-c3ccccc3C#N)cc2)n1 +Cc1c(C(=O)N2CCN(c3ccccc3)CC2)[nH]c2c1C(=O)CCC2 +CC(C)c1ccc(NC(=O)Cc2nnc(-c3ccsc3)o2)cc1 +CNC(=O)CCN(C)C(=O)c1ccc(C(C)(C)C)cc1 +Nc1ccccc1-c1nnc2sc(-c3cccc(O)c3)nn2c1=O +Cc1cc(C)n(-c2cccc(-c3nccn3Cc3cc(=O)[nH]cn3)c2)n1 +CC(C)(C)C(=O)N1CCC(C(=O)OCC(N)=O)CC1 +c1ccc(C(Sc2ncn[nH]2)c2ccccc2)cc1 +O=C(c1ccc(F)cc1)N1CCCC1c1ccncc1 +O=C(CSc1ncn[nH]1)NCC(=O)Nc1ccc(F)c(F)c1 +Cc1cccc2c1CCNC2c1c(C)ncnc1C +COC(=O)c1cccc(CCNC(=O)NC2C3CCOC3C2(C)C)c1 +COc1ccc(N2CC(C(=O)Oc3cccc(F)c3)CC2=O)cc1 +CCC(C)Nc1nnc(-c2cnc(N(C)C)s2)s1 +O=C(NCCCc1ccco1)c1ccc2nccnc2c1 +CC1Cc2ccccc2N1C(=O)C1CC(=O)N(C2CCCC2)C1 +Cc1cc(C2CCCN2C(=O)c2ccc3sccc3c2)on1 +CN(C)c1cc(C(=O)N2CCCC(n3cccn3)C2)ccn1 +Nc1cc(Cl)ccc1S(=O)(=O)NCc1ccco1 +CCCN(CCC)C(=O)Cn1cnc(C#N)c1C#N +NC(=O)COc1cccc(COC(=O)c2ccccc2)c1 +O=c1c2c3c(sc2ncn1CCc1ccncc1)CCCC3 +COc1ccc(NC(=O)NCCSc2ncn[nH]2)c(C)c1 +CC1CC2CN(C(=O)c3cc4cc(Cl)ccc4o3)CCC2O1 +Cc1nnc2n1CCN(C(=O)C(C)OCC(C)C)C2 +CCCn1nc(C#N)cc1-c1ccc2c(c1)CC(=O)N2C +COC(=O)C(C)NC(=O)N1CCC(O)(c2ccc(C)cn2)CC1 +C#CCN1CCN(S(=O)(=O)c2ccc(OC)cc2C)CC1 +CCCN(Cc1nc2cc(Cl)ccc2c(=O)[nH]1)C(=O)C1CCCO1 +Nc1ccc2c(c1)OCC(=O)N2CC(=O)N1CCCC1 +COc1ccc(N2CC(NC(=O)Nc3ncccc3C)CC2=O)cc1 +COC(=O)C1CCN(C(=O)C(C)Sc2ccc(Cl)cc2)CC1 +O=C(NCCc1cccc(O)c1)NCc1cn(-c2ccccc2)nn1 +CCCC1CN(C(=O)CCc2nc3c([nH]2)c(=O)[nH]c(=O)n3C)CCO1 +Cn1c(Cn2cnc(C#N)c2C#N)nc2cc(Cl)ccc21 +CC(C)(CNC(=O)NCCCN1CCOCC1)c1ccccc1 +Cc1ccc(C(=O)N2CCN(C(C)c3nc(C4CC4)no3)CC2)s1 +O=C(NCc1ccco1)c1cc(-c2ccccc2)on1 +Cc1cccc(OC(C)C(=O)Nc2c(C)cccc2C)c1 +CN(CCOc1ccc(F)cc1)C(=O)c1scnc1C1CC1 +O=C(c1c(F)cc(Br)cc1F)N1CCCC(O)C1 +CN(C)c1ccc(C(=O)N2CCn3c(-c4ccccc4)cnc3C2)cc1 +CCOc1cc(C(=O)N(C(C)C)C2CCOCC2)ccc1C +Cc1ncsc1CN1CC2CN(S(C)(=O)=O)CCOC2C1 +Cc1ccc2cccc(Oc3ncnc4c3cnn4C)c2n1 +CC(C)(C)c1nc(Cn2cnc3sccc3c2=O)cs1 +COc1ccc(C2CCCN2C(=O)c2cc(C3CC3)[nH]n2)c(OC)c1 +Cc1cc(NC(=O)CSc2nc(C)cc(N)n2)on1 +O=C(COc1ccccc1)Nc1cc(F)c(F)c(F)c1 +COc1ccc(C(=O)N2CCCCCC2c2c(C)n[nH]c2C)nn1 +Cc1csc(C2CCCN(Cc3cccc4c3OCO4)C2)n1 +Nc1cccnc1SCCOc1ccc(Cl)cc1 +Cc1nonc1CN(C)C(=O)c1cn(CC=Cc2ccccc2)nn1 +O=C(CC1C=CCC1)NCc1ccc2[nH]c(=O)[nH]c2c1 +CC(=CC(=O)OCCOC(N)=O)c1ccc(F)cc1F +CC(=O)N1CCN(C(=O)C2CCCC2)CC1c1nc2ccccc2[nH]1 +Cc1cccc(CNC(C#N)c2ccc3c(c2)OCO3)c1 +CC#CCSc1nc2sccc2c(=O)n1C +Cc1cccc(CC(=O)NCCn2ccc(C(F)(F)F)n2)c1 +COc1ccnc(N2CCN(C(=O)NCc3sccc3C)CC2)n1 +CNC(=O)Cc1ccc(NC(=O)COc2c(C)cccc2C)cc1 +O=C1CCCN1CCC(=O)N1CCCC1c1nc2ccccc2[nH]1 +O=C(c1cccc(F)c1)N1CCCC1c1nc2ccccc2[nH]1 +CCOC(=O)c1ccc(NC2=NS(=O)(=O)c3ccccc32)cc1 +Cc1cccc(NC(=O)NCc2ccco2)c1C(=O)N1CCCC1 +CCCNC(=O)C1(NCc2nnc(C(C)(C)C)o2)CCCCC1 +CCC(C)n1ncc(C(=O)C(C#N)c2ccccn2)c1C1CC1 +CC(=O)NCc1ccc(C(=O)N(C)Cc2ccc(C(C)(C)C)cc2)o1 +CCN(CC)C(=O)c1c(-c2ccccc2)csc1NC(C)=O +Cc1cccc2c(=O)n(CC(=O)N(C)C(C)CC(C)C)cnc12 +C#CCNC(=O)Cn1c(=O)n(CC=C)c(=O)n(CC=C)c1=O +O=C(CSc1ccc(O)cc1)N1CCC(n2cccn2)CC1 +Cc1cc(C)c(CNC(=O)c2ccc(Br)cc2)c(=O)[nH]1 +Cc1nc(Cc2ccc(F)cc2)sc1C(=O)N(C)C(C)C +COc1ccc2c(=O)n(CC(C)C#N)ccc2c1OC +Cc1cc(Cl)ccc1OCC(=O)NCC1(C(N)=O)CCOCC1 +Cc1ccc(-c2nc(C)sc2Cc2nnc(N)o2)cc1 +O=C(COC(=O)c1cc(O)c2ccccc2c1O)NCC1CCCO1 +O=S(=O)(c1cc(F)ccc1Cl)N1CCC(n2cccn2)CC1 +CNc1nc(-c2ccc(C(C)(C)C)n(C)c2=O)cs1 +O=C(Cc1c(F)cccc1F)Nc1cnccc1-n1ccnc1 +COC(=O)CCC(=O)NC(C)c1ccc(Cl)cc1Cl +CCCCN(C)C(=O)Nc1ccc(N2CCCC2=O)cc1 +Cc1cc(C(=O)NCC(C)COCc2ccccc2)[nH]n1 +N#Cc1cccnc1NCC1CCN(c2cnc3ccccc3n2)C1 +COc1cc2c(c(OC)c1)C(Cc1ccc(O)cc1)NCC2 +Cc1cc(NC(=O)COc2ccnc3ccc(Cl)cc23)no1 +O=c1onc(-c2cccnc2)n1Cc1cc(=O)n2ccccc2n1 +CNc1snc(C)c1C(=O)NCC1CCC(C)CC1 +CC(C)NC(=O)C1CCN(c2ccccc2F)CC1 +Cc1cccc(NC(=O)Cn2nc(-c3cccs3)ccc2=O)c1C +CCc1nncn1CCNC(=O)c1nc(C)n(-c2ccc(F)cc2)n1 +CCCNC(=O)CCNC(=O)Nc1ccc(C(C)C)cc1 +Fc1cccc(Cn2nnc(-c3ccsc3)n2)c1 +Cc1scc(C(=O)N2CC(C)(C)C(C)(O)C2)c1-c1ccccc1 +CCc1noc(-c2csc(C(=O)NCc3ccccc3)n2)n1 +COC(OC)(OC)C(C)(C)c1ccc2c(c1)oc(=O)n2C +CCN(CC)C(=O)c1cccc(-c2ccc3c(cnn3C)c2)c1 +O=C1CCC(C(=O)NC2(c3ccc4c(c3)OCCO4)CCCC2)N1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)N3CC(C)c4ccccc43)ccc21 +Cn1cc(S(=O)(=O)NC2CCCN(C(=O)c3ccccc3)C2)cn1 +CCC(C)C(=O)NCC(=O)NC1C(C)CCCC1C +Cc1cccc(NC(=O)c2cnn(-c3ccccc3C)c2C)n1 +N#Cc1cccc(C(=O)NCC(=O)OCc2ccccc2)c1 +COc1ccc(C2NC(=O)N(C)C3=C2C(=O)OC3)cc1 +COc1nc(N2CCC(CC(N)=O)CC2)ncc1Br +CC(c1ccc(Cl)cc1)N(C)C(=O)c1ccc[nH]c1=O +CCN(CC)C(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1F +CCc1nn(CC(=O)N2CCCCC2)c(=O)c2cc3ccsc3n12 +CCOC(=O)c1ccccc1NC(=O)c1cnccc1C(F)(F)F +O=C(Nc1nncs1)NC(CCn1cncn1)c1ccccc1 +O=C(Nc1ccc(-n2cncn2)cc1)c1cc(Cl)ccn1 +N#Cc1ccc(NC(=O)CCCNC(=O)c2ccco2)cc1Cl +CCc1noc(C(C)N2CCN(c3cccc(OC)c3)CC2)n1 +Cc1ccc(NS(=O)(=O)c2ccc(C)c(C(=O)N(C)C)c2)cc1 +CC(C)N(Cc1cnn(C)c1)C(=O)CCC(=O)c1ccc(F)cc1F +Cn1cc(C(=O)NCc2ccc3c(c2)OCO3)c2ccccc2c1=O +CCOC(=O)c1csc(NC(=O)c2c[nH]c3ccccc3c2=O)n1 +Cc1nn(C)c2ncc(NC(=O)CSc3nncs3)cc12 +CN(Cc1ccccc1)C(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +CC(C)C(=O)Nc1cccc(CNC(=O)c2cccc(C#N)c2)c1 +Cc1cccc(OCCn2nnc(CO)c2-c2cccs2)c1 +CC1CC(C(N)=O)c2ccccc2N1Cc1ncc(C(C)(C)C)o1 +Cc1ccc(OC2CCN(Cc3sc(N(C)C)nc3C)CC2)cc1 +N#CCCCN1CCCc2c(NC(=O)c3ccc(F)cc3)cccc21 +CCC(=O)N1CCCC2(C1)N=C(c1ccccc1)C(=O)N2 +COc1cc(CNC(=O)NC(C)c2cc3ccccc3o2)ccn1 +Nc1ccc2c(c1)N(C(=O)CCc1cccc(Cl)c1)CC2 +Cc1c(C(=O)N(C(C)C)C(C)C)cnn1CCOC1CCCCO1 +O=C(Nc1cccnc1N1CCCCC1)c1cn2cccnc2n1 +CCCC(=O)Nc1cccc(NC(C)C(N)=O)c1C +COc1ccc(NC(=O)c2ccc(S(=O)(=O)N(C)C)cc2)cn1 +CN(CC1CCCN(c2ncccc2C#N)C1)C(=O)OC(C)(C)C +CC1Cc2ccccc2N1C(=O)C1CC1c1ccco1 +CCN(CC(=O)Nc1cccc(OC)c1)C(=O)c1cc(C(C)C)[nH]n1 +CC(C)Cn1nc(-c2ccc(C#N)cc2)ccc1=O +COC(=O)CC(NC(=O)c1ccc(N(C)C)cc1)c1ccc(F)cc1 +COc1ccc(NC(=O)CN2CCOCC2C2CC2)c(OC)c1 +O=C(c1ccccc1)N1CCN(C(=O)c2cc(C3CC3)[nH]n2)CC1 +Cc1nn(C)cc1C(=O)Nc1cccc(-c2cn[nH]c2)c1 +O=C(c1cccnc1-n1cncn1)N1CCC(N2CCNC2=O)CC1 +Cc1ccccc1SC(C)(C)C(=O)N1CCNCC1 +O=C(NCCO)c1ccc(COc2ccccc2)cc1 +COCCN1C(=O)CCCC12CCCN(c1cccnc1)C2 +CC(CCC(C)(C)C)NS(=O)(=O)c1cccc(S(C)(=O)=O)c1 +Cn1cnnc1CNc1ncc(Cl)cc1Cl +COc1ccc(C(C)NC(=O)Nc2nnc(C3CC3)s2)cc1F +CC(C)NC(=O)Nc1ccc(NC(=O)Cc2c(F)cccc2F)cc1 +Cc1cc(C)c(CNC(=O)N(C)C(C)c2cccs2)c(=O)[nH]1 +Cc1nc(C)n(CC2CN(C(=O)CCc3ccc(F)cc3)CCO2)n1 +O=C(CNc1ccc(Cl)c(Cl)c1)N1CCCCC1 +NC(=O)c1cccc(CNS(=O)(=O)c2ccc3c(c2)CCCC3)c1 +COC(=O)C(NC(=O)Cc1noc2ccccc12)C(C)C +CNC(=O)c1ccc(CNC(=O)C2CCOC2)cc1 +CCN(CC)C(=O)c1ccc(=O)n(-c2ccccc2)c1 +CC1CN(C(=O)c2ccoc2)CCN1C(=O)c1ccoc1 +O=C(Cn1cccn1)NCC#CCOc1cccc2ccccc12 +CN(C)C(=O)c1cc(OC2CC2)cnc1S(N)(=O)=O +CC(C)(C)Cc1nnc(NCc2cscn2)o1 +C=CCN1CC2(CCN(C(=O)c3ccc(OC)cc3)CC2)OCC1=O +CCc1cc(C(=O)NCC2(C(N)=O)CCOCC2)sc1C +CC(=O)NCCC(=O)NCCOc1ccc(Cl)cc1 +CCOC(=O)c1csc(NC(=O)c2cccc(OC)c2F)n1 +CCN(CC)C(=O)Cn1cc(C(=O)N2CC(C)OC(C)C2)nn1 +CCCN(CCC)C(=O)c1ccc(N)c(Br)c1 +Cc1cccn2c(CC(=O)N3CCCC4(CCOC4)C3)cnc12 +C=CCn1c(SCCO)nc2c1c(=O)[nH]c(=O)n2C +Cc1noc(NC(=O)c2ccc(OCC(F)(F)F)nc2)n1 +Cc1ccc(S(=O)(=O)NCCNC(=O)c2ccccc2)c(C)c1 +CCS(=O)(=O)N1Cc2ccccc2CC1C(=O)NCCOC +Cc1ccc2nc(SCC(=O)N3CCC(C(N)=O)CC3)[nH]c2c1 +CCC(C)NC(=O)CSc1nncn1-c1ccc(OC)cc1 +CC(C)C(=O)N1CCC(c2nc(-c3ccc(C#N)cn3)no2)CC1 +CC(OCC1CC1)C(=O)N=c1[nH]nc(-c2ccccc2Cl)[nH]1 +Cc1ccccc1NC(=O)C(C)CS(=O)(=O)N1CCNCC1 +CC(=O)N1CCCC1C(=O)NC1CCc2nnc(C)n2C1 +OC(CN1CCN(c2cccc(Cl)c2)CC1)Cn1cccn1 +Cc1cc(=O)[nH]c(C2CCN(C(=O)c3cscn3)CC2)n1 +COC(=O)C1C(=O)N(C)C(c2ccccc2)C1C(=O)OC +Cc1cn(CC(=O)N(C)CC2(CO)CCOCC2)c(=O)[nH]c1=O +CCCc1nc(NC(=O)c2cc(C(C)=O)c[nH]2)sc1CC +O=C(Nc1ccnc2ccnn12)C1(c2ccc(Cl)cc2)CC1 +CCNC(=O)CNC(=O)COc1ccc2c(c1)CCC(=O)N2 +COC(=O)C(C)NCc1cnn(Cc2ccccc2)c1 +COc1ccc(C(=O)c2ccc(OC)c(N)c2)cc1C +CC(NC(=O)c1ccc(N)nc1)c1ccccc1Cl +c1nc2c(c(NC3CCc4ncnn4C3)n1)CCC2 +CN(Cc1ccncc1)C(=O)c1ccc(-c2ccc(F)cc2)o1 +CCC1(C)Nc2ccccc2N(Cc2cccc(C#N)c2)C1=O +COc1ccc(NC(=O)Cc2ccccc2O)cc1OC +CCNc1ncccc1S(=O)(=O)N(C)C(C)C(C)C +O=C(Nc1ccc2ccccc2n1)c1cc(C2CC2)on1 +Cc1ncsc1CCOC(=O)C1CCCN1C(=O)c1ccco1 +Cc1nc(N(C)C)sc1C(=O)NCc1cccnc1-n1cccn1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1cccnc1 +CCOC(=O)N1CCC(NC(=O)Nc2ccc(C(=O)OC)cc2)CC1 +CCc1nsc(N2CCCN(C(=O)NCc3ccco3)CC2)n1 +CC(Sc1nnc(-c2ccccc2)o1)C(=O)N(C)CCC#N +O=C(NCCOc1ccc2ccccc2c1)c1cccnc1 +CC(=O)N(CCc1ccccc1)CC(=O)N1CCCC2CCCC21 +Cc1noc(C)c1CCC(=O)N(CC1CCCCC1)C1CC1 +C#CCC(OC(=O)c1scnc1C1CC1)c1ccccn1 +CC(C)(C)OC(=O)N1CCC2(CCC(=O)N2)CC1 +COc1ccc2nc(N(CC3CCCO3)C(C)=O)sc2c1 +Cn1cnnc1-c1ccc(NC(=O)c2ccc(C(F)(F)F)nc2)cc1 +Cc1ccc(NC(=O)c2cccn(C)c2=O)cc1N1CCCCC1=O +CCN(CC(=O)NC(C)C(=O)N1CCCCC1)c1ccccc1C +CCCCSc1ncc(C2CC(=O)Nc3snc(C)c32)cn1 +CC(c1ccccc1F)N(C)C(=O)Cn1cnnn1 +CS(=O)(=O)N1CCOCC2(CN(Cc3ccco3)CCO2)C1 +CCC(C)OC(=O)CC1C(=O)NCCN1C(=O)NC1CCCCC1 +COc1cc(NCc2ccc(-n3ccnc3)cc2)cc(OC)c1 +O=C(Nc1ccccc1N1CCCC1)c1cc(=O)[nH]c2ccccc12 +CCOC(C)c1nccn1Cc1cc(-c2cccs2)on1 +Cc1ccccc1CNC(=O)NCC1CN2CCCCC2CO1 +CCOCCCC(=O)N1CCC(C(N)=O)c2ccccc21 +N#Cc1ccc(OC(=O)C2CCCN2C(=O)c2cccs2)cc1 +CCOc1ccc(NC(=O)CNS(C)(=O)=O)cc1Cl +CCC(=O)Nc1ccc2c(c1)N(C(=O)C1CC1)CC2 +COCCOc1ncccc1C(=O)Nc1c(C)cccc1C +CCn1nc(C(=O)NCc2ccc(OCc3ccccc3)cc2)cc1C +CCNC(=O)C1CCCN(c2nc3ccc(C)cc3s2)C1 +O=C(Nc1ccccn1)C1CC(=O)N(c2ccccc2Cl)C1 +O=C(CNS(=O)(=O)c1ccccc1)NCc1ccccc1Cl +Cn1cnc(CNC(=O)Nc2cccc(N3CCCCCC3)c2)n1 +CC(=O)N1CCN(C(=O)c2ccn3nnnc3c2)CC(O)C1 +CC(=O)N1CCc2ccc(NC(=O)CC3CCCC3)cc21 +CC1(C)CCCC1NC(=O)c1cccc(OCC(F)F)n1 +CCCC(=O)N1CCCCC1C(=O)Nc1cc(F)cc(F)c1 +COC(C)(C)c1noc(-c2cc(=O)c3ccccc3o2)n1 +Cc1ccc(C(=O)CSc2nccn2C)c(C)c1 +Cc1ncccc1C(=O)N1CC(=O)Nc2cccnc21 +Cc1cc(CSc2nncn2-c2ccccc2)on1 +O=C(NC1CC1c1cccc(Cl)c1)c1ccoc1 +CN(CCc1ccccc1)C(=O)NCc1ccnn1C +CCc1nc(CC(=O)Nc2cc(F)cc(F)c2)cs1 +CC(C)N1CC(C2NCCc3c(N)cc(F)cc32)CC1=O +Cc1ccn2cc(C(=O)N(C)CCOc3ccccc3)nc2c1 +Cn1nnnc1SCC(O)CN1CCOCC1 +CC(C)(C)OC(=O)N1CCCC(CSc2cnccn2)C1 +O=C(NC(CCCO)c1ccccc1)N1CCCC1c1ccc[nH]1 +Cc1cc(C)n(-c2ccc(NC(=O)CCn3cncn3)cc2F)n1 +COC(=O)c1ccc(Cc2nc3sc(C)c(C)c3c(=O)[nH]2)o1 +CC(=O)Nc1ccc(SC(C)C(=O)N(C)c2ccccc2)cc1 +O=C(NC1CCN(c2c(F)cccc2F)C1=O)C1CCOCC1 +CCOC(=O)C1CCCN(S(=O)(=O)c2ccc(OC)c(C)c2)C1 +O=C(CNC(=O)C1CCCC1)Nc1cccc(Oc2ccncc2)c1 +Cc1cc(C)n2cc(CN3CCN(Cc4cccs4)CC3)nc2n1 +COc1cc(C#N)ccc1OCC(=O)Nc1cc(C)nn1C +Cc1n[nH]c(=O)c2c(NC(=O)CSc3ccccc3F)oc(C)c12 +CCc1ccc(C(=O)NCc2nnc3n2CCC3)o1 +CC(C)(C)CCS(=O)(=O)NCC1(C(N)=O)CCOCC1 +O=C(CCOc1cccc2ccccc12)N1CCN(CCO)CC1 +Cc1ccccc1-c1nc(C(=O)NCCOc2cccnc2)cs1 +CCOCCC(=O)Nc1cc(-c2ccccc2)ns1 +COc1cc(C(=O)NC2CCCCC2)cc(Cl)c1OC +COCCN(Cc1ccccc1)C(=O)NCc1ccccn1 +Cc1ccc(C(=O)Nc2cc(C(F)(F)F)c[nH]c2=O)c(O)c1 +O=C(CN1CCOCC1)c1cc2c(cc1Cl)OCO2 +CCn1ncc2c1C(COCC1CC1)CN(c1ccncn1)C2 +CCN(CC(C)C#N)C(=O)CNc1cc(Cl)cc(Cl)c1 +O=C1NCC2(CCN(C(=O)C3CC3)CC2)Oc2ccccc21 +CC(C)n1cc(Br)cc1C(=O)N(C)Cc1ccsc1 +COc1ccc(C)cc1S(=O)(=O)NCC(N)=O +CCC(CC)C(=O)N1CCC(NC(=O)C2CCC2)CC1 +CC(=O)c1csc(Cc2ccc3c(c2)OCO3)n1 +CCc1onc(C)c1NC(=O)NCC1(c2cccc(F)c2)CC1 +CCc1ccc(CNC(=O)c2cc(NC(C)=O)ccc2O)s1 +CC(C)N(C)C(=O)C1CC(=O)N(C2CCCCC2)C1 +COCC(NC(=O)c1cnc(C2CCCO2)s1)c1ccc(C)o1 +Cc1cc2nc(C)c(CC#N)n2cc1Br +COCC(C)NC(=O)C(C)Oc1cccc2ccccc12 +CC(C)c1nnc(NC(=O)c2cc(F)ccc2-n2cnnn2)s1 +CCn1c(CNC(=O)N2CCCCC2)nnc1SC +CCN(CCc1ccncc1)C(=O)CCc1ccc(O)c(N)c1 +O=C(Nc1cccc(C(F)(F)F)c1)c1ccc2nccnc2c1 +Cc1cc(NCCCCCN2CCOCC2)nc(N)n1 +COc1ccc(CC(=O)N(C)C(C#N)c2ccccn2)cc1 +Cc1ccccc1Nc1nc2nonc2nc1-n1ccnc1C +CC1CCN(C(=O)CC2C=CCC2)C(c2ccco2)C1 +NC(=O)c1ccc(NS(=O)(=O)c2cccc(N)c2)cc1 +CC(=O)c1cc(Br)ccc1NCc1nnc(C2CC2)o1 +C=CCNS(=O)(=O)c1cccc(C(=O)NC(C)CC)c1 +Cc1nn(C)c(C)c1NC(=O)C(C)Nc1cccc(Cl)c1C +O=C(CCOCC1CCCO1)N1CCC(Nc2ccccc2)C1 +C=CCn1c(NCc2ccc(C)o2)nc2ccccc21 +CC(=O)c1nc2cc(F)ccc2n1-c1ccc(C#N)cn1 +O=C(NCCC(O)c1cccs1)c1ccc(Cl)cc1Cl +COc1ccc(OC)c(Nc2ncnc3cc(OC)c(OC)cc23)c1 +COCc1ccccc1NC(=O)Cc1cccc(OCC#N)c1 +CN(C)c1cc(C(F)(F)F)cc(-c2cccc(C(N)=O)c2)n1 +CC(=O)NC(C)C(=O)NCCc1cc(Cl)c2c(c1)OCCO2 +CCN(CC(O)c1ccc(C)cc1)C(=O)c1ccc2cc[nH]c2c1 +CCn1c(=O)n(CC(=O)N2CCOCC2C2CC2)c2ccccc21 +O=C(Cn1c(=O)oc2ccccc21)N1CCN(C(=O)C2CC2)CC1 +CCn1cc(CC(=O)Nc2ccc(F)cc2F)c2cccnc21 +COC(=O)COc1ccc(S(=O)(=O)NC2CCCCC2)cc1C +Cc1ccc(CN(C)C(=O)c2cc(Br)ccc2F)o1 +CC1(C)C(C(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)C1(C)C +CCOc1ccccc1CNC(=O)C1CCN(C(=O)OC(C)(C)C)C1 +Cc1ccc(C#N)cc1NC(=O)c1cc2c(cc1Cl)OCCO2 +Cc1cccc(OCCn2c(=O)oc3ccc(N)cc32)c1 +COc1ccc(C(=O)COC(=O)c2[nH]nc3ccccc23)c(OC)c1 +CC(=O)c1cc(-c2ccc(Br)cc2)n(C)c1C +CCOc1ccccc1OCC(=O)Nc1ccc2c(c1)OCCO2 +Cc1ccc(NC(=O)Cn2nc(-c3ccco3)ccc2=O)cc1F +Cc1ccc(N2CC(C(=O)NC3(C)CCOC3)CCC2=O)cc1C +O=C(CNC(=O)C1CCCC1)NCc1ccccc1-n1ccnc1 +Cc1ccc(CNCC(O)c2ccc(Cl)cc2)cc1 +CCOC(=O)c1cc(-c2ccccc2OCC2CCCO2)nc(N)n1 +Cc1c(C(=O)Nc2ccccc2O)sc2ncn(C)c(=O)c12 +CC(C)(C)S(=O)(=O)c1ccc(N2CC3CCC2C3)cn1 +N#CC1(NC(=O)CNC(=O)c2ccccc2)CCCC1 +O=C(c1n[nH]c(=O)c2ccccc12)N1CCCC1c1ccsc1 +CCOCCNC(=O)c1cccc(-n2cc(Br)cn2)c1 +Cn1cnc(CNC(=O)c2cccc(-n3cccn3)c2)n1 +O=C(CCc1nc(-c2ccccc2)no1)NC1CCCCNC1=O +CCCC1CN(C(=O)c2ccc(C)c(C)c2O)CCO1 +CS(=O)(=O)N1CCCC(C(=O)Nc2ccc(F)cc2Cl)C1 +Cn1nc(C2CCCN(C(=O)CC3CCCCC3)C2)c2nccnc21 +COc1ccccc1CSc1nnc(NC2CC2)s1 +Cc1cc(NC(=O)CN2CCc3ccc(Cl)cc3C2)n(C)n1 +CC1CCN(C(=O)CNc2ccccc2C(=O)N(C)C)CC1 +CCCn1ncc(C(=O)Nc2cc(F)ccc2OC)c1C1CC1 +CCCCn1c(C)c(C)n2c3c(=O)n(CC)c(=O)n(C)c3nc12 +Cc1ccccc1NCc1nnnn1-c1ccccc1 +Cc1nc(Nc2ccc(F)cc2)nc2c1C(=O)CCC2 +CC1CN(Cc2nc(N)nc(Nc3ccc(Cl)cc3)n2)CC(C)O1 +CCCOc1ccc(OCC(=O)N2CCNCC2)cc1 +COCCC(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +CCn1c(SCC(=O)NC)nc2c(c1=O)SC(C)C2 +O=C(NCC(O)COc1cccc(F)c1)NC1CCCCNC1=O +CCc1nncn1CCNC(=O)c1c(O)cc(Cl)cc1Cl +O=C(CSc1ccc(F)c(F)c1)N1CCCC1 +Cc1ccc(COC2CN(C(=O)c3ccccc3Cl)C2)cc1 +CCn1c(CN2CCCCC2C(N)=O)nc2cc(F)ccc21 +CCOCCCNC(=O)c1n[nH]c2ccc(N)cc12 +COCc1ccccc1C(=O)N1CCCC(NS(C)(=O)=O)C1 +C=CCCC1NCCc2ccc(OC(F)F)c(OC)c21 +CCCCNC(=O)Cn1nnc(-c2ccccc2C)n1 +c1cc(-c2noc(CN3CCN(Cc4cscn4)CC3)n2)cs1 +CC(=O)c1cccc(-n2nnc(-c3ccncc3)c2N)c1 +O=C(NC1CCCOc2ccccc21)c1ccnc(-n2cncn2)c1 +COc1ccc(F)c(NC(=O)N2CCN(C(=O)c3ccoc3)CC2)c1 +COc1cccc(CC(=O)NC(C)c2nc(-c3cccnc3)n[nH]2)c1 +COC(=O)c1cc(CNC(=O)NCc2ccccc2F)oc1C +CSc1ccccc1C(=O)Nc1nnc(-c2cc(C)oc2C)o1 +Cc1cc(C)nc(N2CCC(N3CCNC3=O)CC2)n1 +Cc1nn(CC(=O)Nc2cccc(Cl)c2F)c(=O)c2ccccc12 +COC(=O)C1(NC(=O)c2ccoc2C)CCCC1 +Cc1ncccc1C(=O)N1CCOc2ccc(F)cc21 +O=C(CN1CCOC(c2ccc(Cl)cc2)C1)Nc1cccnc1 +CN(Cc1cccn1C)C(=O)c1scnc1C1CC1 +O=C(OCCN1CCOC1=O)c1ccccc1F +CCc1ccc(Oc2ncnc(N(CC)CCO)c2N)cc1 +O=C(Nc1ccc(Cl)cc1)Nc1nncs1 +COC1CCCCC1OC(=O)c1cnn2cccnc12 +OCCCc1csc(CCOc2ccc(Cl)cc2)n1 +NC(=O)Cc1ccccc1NCc1ccc(F)cc1Cl +COC(=O)c1ccc(NC(=O)c2cccc(OC)c2)cc1 +CCOC(=O)CN(C(=O)c1cc(-c2ccncc2)on1)C1CC1 +CCOc1ccccc1NC(=O)c1nn(CC)cc1Br +O=C(NC1CCCC1)c1cc(C#CCO)ccc1F +Cc1cc(C)n(CC2CN(CC(=O)NC3CCCC3)CCO2)n1 +COc1ccc(N)cc1CNS(=O)(=O)c1cccc(Cl)c1 +COCCn1ccc(NC(=O)N(C)C(C)c2cccc(O)c2)n1 +Cc1cc(C)n(CCNC(=O)COc2c(C)ccc(C)c2C)c(=O)n1 +COC(=O)CC(NC(=O)c1ccoc1)c1ccc(C)cc1 +CCCS(=O)(=O)NCCN1CCN(C(=O)c2ccsc2)CC1 +CCCn1ccc2ccc(NC(=O)NCc3ccco3)cc21 +CC(=O)NCCc1cn(-c2cnc3ccccc3c2)cn1 +CC1Oc2cc(O)ccc2N(CC(=O)N2CCCC2)C1=O +CNC(=O)c1cccc(OCC(=O)N(C)C(C)c2ccccc2)c1 +CCOCC(=O)N1CCCc2ccc(S(=O)(=O)N(C)C)cc21 +COc1cccc(-c2nn(-c3ncccn3)c3c2CNCC3)c1 +COc1ccc(CC(C#N)C(=O)NCC(C)C)cc1O +COc1ccc(S(=O)(=O)NCCn2ccnc2)c(C)c1 +O=C(COc1cccc(N2CCCC2=O)c1)Nc1ccc(F)cc1 +CC(C)COC(=O)N1CCCN(C(=O)c2ccccn2)CC1 +CCOc1ccccc1C(=O)Nc1ccccc1C#N +COCCN(Cc1ccsc1)C(=O)c1c(F)cccc1Cl +CC(C)CN(C)C(=O)c1c[nH]c2ccccc2c1=O +Cn1ccsc1=NC(=O)c1cccc(S(C)(=O)=O)c1 +CCN(CC)S(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +COc1ccc(CNC(=O)c2ccc(C)cc2O)cc1OC +CCCNC(=O)CSc1nnc2[nH]c(=O)c3c(n12)CCCC3 +CC(=O)c1cnc2cc(-c3cccc(Br)c3)nn2c1C +Cc1ccc(CC(=O)N2CCCCC2CO)cc1C +CC(=O)NCCOc1ccc(-c2nc(C3CCOC3)no2)cc1 +Cc1cc(C(=O)Nc2nnc(-c3ccco3)o2)no1 +CCCn1nnnc1NCc1cc(Br)ccc1OCC +CC(Cc1ccccc1)NC(=O)c1cc(Br)cn1C +CC(C)c1ccsc1C(=O)NCCc1ccco1 +C=CCNC(=O)C(C)NS(=O)(=O)c1ccc(NC(C)=O)cc1 +COC(=O)C1=C(C)N(C(C)C)C(=O)NC1c1ccc(OC)c(OC)c1 +COc1cc(N)c(C(=O)Nc2ccccn2)cc1OC +N#Cc1ccc(NCCNC(=O)c2cccnc2)cc1C(F)(F)F +CCOc1ncnc2c1CN(Cc1cc(C)on1)CC2 +C=CCOc1ccccc1CN(C)Cc1nccs1 +COc1cccc(CC2CN(Cc3cccnc3)CCO2)c1 +COCCCNC(=O)CN1CCN(C(=O)c2ccccc2O)CC1 +C=CCOc1cccc(NC(=O)NCC(=O)Nc2ccccc2)c1 +O=C(CNc1cccc(F)c1)N(Cc1ccccc1)C1CC1 +CCn1cc(S(=O)(=O)NC2(CO)CCCC2)nc1C +CCc1nc(Cc2ccc(OC)c(OC)c2)sc1C(C)=O +COCCC1(C(=O)NC(C)Cn2nc(C)cc2C)CCCC1 +O=C(OCC(=O)N1CCc2sccc2C1)c1ccc(O)cc1O +Nc1nc2ncn(C3OC(CO)C(O)C3O)c2c(=O)[nH]1 +C=CCNC(=O)C1CCCCN1C(=O)c1cccs1 +COCCCNC(=O)c1cc(-c2ccc(OC)cc2)nn1C +COCC1CN(C(=O)c2cccc(C)n2)Cc2ncnn2C1 +CCN(Cc1ccccc1C)C(=O)CC(NC(N)=O)c1cccs1 +O=C(NCc1ccoc1)c1cncn1-c1ccccc1 +CCOc1ccc(-c2csc3nc(N)cn23)cc1C +CC1CN(C(=O)c2ccccn2)CCN1C(=O)OC(C)(C)C +O=C(NCC1CC1)N1CC=C(c2ccccc2)CC1 +Nc1nc(CN2CCOCC2)nc(NCc2ccccc2)n1 +O=C(COc1cccc2c1NCCC2)NC1CCCC1 +CNc1snc(C)c1C(=O)NC(C)c1ccccc1-n1cccn1 +CC(C)CNC(=O)Nc1cccc(CN2CCCCC2=O)c1 +COC(CNC(=O)c1snnc1C)c1ccc(C)s1 +CN(Cc1cccnc1)C1CN(c2ncccn2)C2CCCOC12 +Cc1ccc(-n2nnnc2CN2CCN(C(=O)C(C)(C)C)CC2)cc1 +COC(=O)C(NC(=O)C1COc2ccc(F)cc2C1)C(C)(C)C +CNc1nn2c(=O)c(Cc3ccccc3)nnc2s1 +Cc1nonc1NC(=O)CC(NC(=O)OC(C)(C)C)c1ccccc1 +CN(C)C(=O)CN1CCN(C(=O)c2c(F)cccc2Cl)CC1 +O=C1COc2cc(NC(=O)C3(c4cccc(Cl)c4)CC3)ccc2N1 +COCCn1c(CNC(=O)c2ccc(OC)cc2)nc2ccccc21 +CC(C)Nc1cccc(CNC(=O)c2ccn(C)c(=O)c2)c1 +CS(=O)(=O)NC1CCCN(C(=O)c2cccnc2)C1 +CCCCn1c(SCC(=O)NC2CC2)nc2ccccc2c1=O +Cc1nnc(NCCCN2CC(C)OC(C)C2)c(C#N)c1C +CCn1nc(C(C)C)cc1C(=O)Nn1c(C)nc2sccc2c1=O +Cc1ccc(NC(=O)c2cc(-c3cccnc3)[nH]n2)cc1Cl +CC(Cc1ccccc1F)C(=O)Nc1ccccc1CC(N)=O +COc1cc(N2CCC3(CCCN(C4CCCC4)C3=O)C2)ncn1 +Cc1cc(C(=O)N2CCN(CCC(=O)N3CCCCC3)CC2)on1 +COC(=O)c1ccc(CNC(=O)CC2CCCO2)cc1 +CCNc1ncc(-c2nccn2CCn2cccn2)cn1 +c1ccc(-c2nc[nH]c2-c2cnc(-c3ccco3)nc2)cc1 +CCOC(=O)Cc1csc(NCc2ccc[nH]2)n1 +CC(=O)c1cc(-c2ccnc(N3CCCC3)n2)c(C)nc1C +CSc1ccc(CN(C)C(=O)c2ccc(SC)cc2)cc1 +CCN(CCC#N)S(=O)(=O)c1cccc(Cl)c1 +CC(C)N(C)C(=O)C1CC(=O)N(C2CCCC2)C1 +Cc1noc(C)c1CC(=O)OC(C(N)=O)c1ccc(F)cc1 +COC(=O)c1ccccc1OCC(=O)NCc1ccc2c(c1)OCO2 +CC(Cc1ccc(O)cc1)NC(=O)NCc1ccccc1Cl +COC(=O)C(C)Sc1nccn1-c1ccccc1 +CCOc1ccc(S(=O)(=O)Nc2ccc[nH]c2=O)cc1 +COc1ccc(N2CCN(C(=O)C3CCCC3)C(C)C2=O)cc1 +CN(Cc1nc2ccccc2s1)C(=O)c1cnn(-c2ccccc2)n1 +COCC(C)NC(=O)NCC(=O)N1CCCc2ccccc21 +Cc1cc(C2CCCN2C(=O)Cc2ccccc2C)no1 +CCC(C)N1CC2OCCN(Cc3cccc(C)n3)C2C1 +CNC(=O)NCC(=O)NC(C)c1ccccc1C(F)(F)F +Cc1nc2cc(NC(=O)Cc3ccc(O)cc3)ccc2o1 +O=S(=O)(c1c[nH]c2ncccc12)N1CCCCCC1c1ccco1 +Cc1ccc(-c2n[nH]cc2CN2CCC3(C2)OCCO3)cc1 +CC1(C)CCC(S(=O)(=O)Nc2cnn(CC(F)(F)F)c2)CC1 +CCOC(=O)CN1C(=O)COc2c(OC)cc(CO)cc21 +O=S(=O)(NC(C1CC1)C1CC1)c1ccc(F)c(F)c1F +CC(C)CNC(=O)CS(=O)(=O)c1nnc(-c2ccccc2)n1C +CCN(C)C(=O)c1cc(OC)c(OCc2ccccc2)c(OC)c1 +CCNC(=O)CNC(=O)NC(C)c1sc(-c2ccccc2)nc1C +Cc1cc(CN2CCN(C(=O)c3cc(Cl)cn3C)CC2)no1 +CCOc1ccccc1NS(=O)(=O)c1ccc(F)c(F)c1 +CCOC(=O)c1ncn(CC(=O)c2cccc(Cl)c2)n1 +CCNc1nc2c(c(=O)[nH]c(=O)n2CCOC)n1C +O=C1CCCc2c1c(-c1cccc(F)c1)nn2CCO +COC(=O)c1ccc(Cl)c(NC(=O)c2ccccc2N)c1 +COc1ncccc1CNC(=O)Nc1cc(Cl)ccc1C +CC#CC(=O)N1CCC2(CC1)CC2C(=O)Nc1ccccc1 +Cc1ccccc1S(=O)(=O)N(C)c1cc(N)ccc1F +Cc1ncsc1CCOC(=O)CNC(=O)C(C)(C)C +Cc1nc(C2CCCN(C(=O)CC3C=CCC3)C2)no1 +CCc1onc(C)c1NC(=O)N1CCC(COCc2ccccc2)C1 +COCC(=O)N1CCN(Cc2ccccc2C#N)CC(O)C1 +Cc1nc(CCc2ccc(Br)cc2)sc1CO +CCC(=O)N(C)c1ccc(Br)cc1Cl +CSc1nc2ccc(NC(=O)COc3cc(C)on3)cc2s1 +N#Cc1cccc(C(=O)NCc2cc(-c3cc4ccccc4o3)on2)c1 +CN(Cc1nc2ccc(Cl)cc2c(=O)[nH]1)CC1CCCC1 +CC(C)CC1(CNC(=O)N2CCC(n3cncn3)CC2)CCCC1 +COC(=O)c1cc(-c2ccc(C)cc2)nc(N2CCOCC2)n1 +CS(=O)(=O)N1CCOCC2(CCN(C(=O)c3cc[nH]n3)CC2)C1 +CCc1nc(CC(=O)NC2CCCC(C(F)(F)F)C2)cs1 +CC1CN(C(=O)Nc2ccc(F)cc2OCC2CC2)CC(C)O1 +CCOCCCn1c(=NC(=O)c2csnn2)[nH]c2ccccc21 +CN(C)C(=O)Cc1ccc(NC(=O)c2scnc2C2CC2)cc1 +O=C(CC1CCCO1)Nc1nc(-c2ccc3c(c2)OCCO3)cs1 +CNC(=O)C1=C(C)Nc2nc3ccccc3n2C1c1cccs1 +COC(=O)c1ccc(CN(C)CCc2ccc(F)cc2)o1 +O=C(CC1CCC2(CC1)CCN(c1ncccn1)CC2)N1CC=CC1 +CNC(=O)c1ccc(CN(C)c2cccc(C)c2)cc1 +CCOC(=O)C(N)Cc1nnc2n(C)c3ccccc3n12 +Cc1nn(C(C)CCNC(=O)c2cc(C3CC3)[nH]n2)c(C)c1Cl +COc1ccc(OC)c(C(C#N)N2CCC(C)CC2)c1 +COC(=O)CCCN1C(=O)C(C)(C)NS1(=O)=O +CCn1nccc1CN(C)C(=O)C(c1ccccc1)c1ccccc1 +CCNC(=O)Cn1c(CNC(=O)C2CCCCC2)nc2ccccc21 +N#Cc1ccc(Cn2c(-c3ccccc3)noc2=O)cc1 +C#CCN1CCN(C(C)C(=O)NCc2ccc(F)cc2)CC1 +CC(=O)c1ccc(NC(=O)CCC(=O)c2cccs2)cc1C +Cc1sc2ncn(CCCCO)c(=O)c2c1C +CCN(CC)C(=O)C1CCCN1C(=O)Nc1cccc(OC)c1 +CC(C)C(=O)C(C#N)c1cccc(Br)c1 +O=C(NCc1ccc(F)cc1)NCc1ncc(-c2ccccc2)o1 +COC(=O)c1c(NC(=O)C2COc3ccccc3O2)sc(C)c1C +N#Cc1c2n(c(=O)n(Cc3cccc(Br)c3)c1=O)CCC2 +O=C(NCC1CCC1)Nc1ccc2nccnc2c1 +Cc1cc(C(=O)Nc2nc3c(s2)C(=O)CC(C)(C)C3)on1 +Cc1ccc(F)c(C(=O)NC2CCN(C(=O)c3ccoc3)CC2)c1 +O=C(NC1C2CCC(C2)C1CO)C1CC2CCC1C2 +CCc1oc2ccccc2c1CN1CCN(c2cnn(C)c2)C(=O)C1 +Nc1nonc1CC(=O)Nc1cccc(C(F)(F)F)c1 +N#Cc1ccc(CNC(=O)Cn2c(=O)[nH]c3ccccc32)cc1 +CC1CCN(C(=O)CN2C(=O)COc3cccc(N)c32)CC1 +COCCN1CC2=C(C1=O)C(c1ccc(F)cc1)NC(=O)N2C +CN(C)C(=O)c1cn(CCC#N)nc1-c1ccc2c(c1)OCCO2 +Cc1n[nH]c(C)c1NC(=O)CN(C)S(C)(=O)=O +Cc1nonc1NC(=O)c1cccc(Br)c1C +COc1ccc(C(=O)NC(C(=O)N2CCCC2)C(C)C)cc1 +CC(C)C(=O)N(Cc1nccn1Cc1ccccc1F)C(C)C +CC(=O)NC(CC(=O)NC(C)c1ccncc1)c1ccc(Cl)cc1 +Cc1ccc(CC(=O)N2CCN(C(=O)Nc3cccnc3)CC2)cc1 +Cc1ccc2ncc(C(=O)Oc3ccc4[nH]ncc4c3)c(=O)n2c1 +COC(=O)c1c(C)[nH]c(C(=O)C(C)N(C)Cc2ccsc2)c1C +CCC(C)n1ncc(C(=O)Nc2ccc(-n3cccn3)cc2)c1C1CC1 +COc1ccc(CN(C)C(=O)Cn2cncn2)cc1F +CC(C)NC(=O)c1ccc(CNC(=O)c2ccn3cncc3c2)cc1 +CC(=O)N(C)C1CCN(C(=O)NC2c3cc(C)ccc3CC2C)CC1 +Cc1nc2cc(NC(=O)NC(C)Cc3ccc(O)cc3)ccc2o1 +O=C(NC1CCCNC1=O)NC(c1ccccc1)C1CCCC1 +Nc1ccc(-c2nnnn2-c2ccc(Cl)cc2)cc1 +O=C(COc1ccc(F)cc1)Nc1ccc(Cn2cccn2)cc1 +Cc1nc2ccc(NC(=O)c3ccc(OCC(N)=O)cc3)cc2s1 +COC(=O)c1cc(OC)c(OC)cc1N(C)S(C)(=O)=O +Cc1ccc(C(O)CNC(=O)c2ccc(Cl)c(Cl)c2)o1 +CCCC(=O)N1CCCC1C(=O)OCc1ccc(OC)cc1 +CS(=O)c1c(Cl)cccc1NC(=O)c1ccc(F)cc1Cl +COc1cc2c(cc1O)CCNC2c1nccs1 +COc1ccc(-c2nc(C)c3c(n2)N(Cc2ccco2)C(=O)CC3)cc1 +COC(=O)CN(c1ccc(F)cc1)S(=O)(=O)c1ccccc1 +CCN(CC(=O)NC)C(=O)c1[nH]nc(C)c1Br +CCC(Sc1nc2ncccc2o1)C(=O)NCCc1ccccc1 +CCOc1cc(C2NC(=O)N(CC)C(CC)=C2C(=O)OC)ccc1O +CC(=O)NCc1ccc(C(=O)N(CC(C)C)CC(C)C)cc1 +C=CCOc1ccc(CN(C)Cc2nnc(C)n2C)cc1Cl +COc1ccc(OC)c(-c2csc(NC(=O)c3cnccn3)n2)c1 +O=C1CCC(n2nc3ccccc3n2)N1CCSc1ccccc1 +O=C(CSc1ccccn1)NCC1CCN(c2ccccc2)C1 +Cc1nn(C)c(=O)c(C(=O)Nc2nnc(C(C)C)s2)c1C +Cc1ccc(F)cc1NC(=O)Cc1ccccc1N +CN(C)c1cnn(CCOC(=O)c2ccccc2)c(=O)c1 +Cc1nc(C(=O)Nc2nc(-c3ccccn3)cs2)cs1 +Cc1ccnc2nc(C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)nn12 +CCCC(CC)NC(=O)c1cncc(C#CCO)c1 +CC(Nc1cn[nH]c1)c1ccccc1C(F)(F)F +Cn1c(SCC(=O)NCCOc2cccc(F)c2)n[nH]c1=O +Cc1ccccc1NC(=O)C1CC(=O)N=C(N2CCOCC2)N1 +CCCCOc1cccc2c1C(c1cnc[nH]1)NCC2 +CCOc1ccc(S(=O)(=O)Oc2ccccc2NC(C)=O)cc1 +COc1ccc(N(C)C(=O)c2ccc3cc[nH]c3c2)cn1 +CCOC(=O)c1cnc2nc3ccccc3n2c1C +COc1ncc(C2NCCc3cccc(F)c32)c(OC)n1 +Cc1noc(CCC(=O)N2CCN(c3cccc(Cl)c3)CC2)n1 +N#Cc1ccccc1C1NCCc2cc(F)c(F)cc21 +Cc1ccccc1C(=O)NCC(=O)NCCCc1ccccc1 +O=C(CCNC(=O)c1ccco1)Oc1cccc(N2CCCC2=O)c1 +Cc1cc(C(=O)NCC(=O)NC2CC2)c(C)n1C1CC1 +CNc1ccc(Cl)c(C(=O)NCC2CCCC2)n1 +COC(=O)c1cccc(C(=O)NCc2ccccc2OC)c1 +CS(=O)(=O)N1CCC(C(=O)NCCCn2cccn2)CC1 +CCOCC(=O)N1CCc2cn(CC)c3cccc(c23)C1 +c1ccc(-c2cnc3nc4ccccc4nc3n2)cc1 +Cc1cnc(NC(=O)NC(C)c2ccc(-n3ccnc3)cc2)s1 +c1ccc(Nc2nccc(C3CCCCN3c3ncccn3)n2)nc1 +Cc1cc(NC(=O)NCc2nc3ccccc3s2)no1 +CCN(CC)C(=O)NCC1(c2ccc(F)cc2)CC1 +CNS(=O)(=O)c1cc(C(=O)Nc2cccc(C)c2C)cc(C)c1C +Cc1cccc(-c2nc(CC(=O)OCCN3CCOC3=O)cs2)c1 +CCOc1ccccc1NC(=O)NCCCn1ncccc1=O +O=C(NCc1nnc2n1CCCCC2)c1cccc2ccccc12 +Nc1ncnc(SCC(=O)c2cccs2)n1 +CCCN(CC1CC1)C(=O)c1cc(-c2cccs2)n[nH]1 +COc1cc(Cl)c(C)cc1NC(=O)CSc1nnc(C)n1N +CC(C)(O)C#Cc1ccc(C(=O)N2CCN(c3ccccn3)CC2)o1 +CC1CCCC(NC(=O)c2scnc2C2CC2)C1 +CN(Cc1cccc(F)c1)C(=O)CCNC(=O)c1ccc(Cl)cc1 +CC(C)NC(=O)Nc1cccc(C(=O)OCc2nccs2)c1 +O=C(CCC1CCCC1)NCc1cc2ccccn2n1 +O=C(CNC(=O)c1cnns1)Nc1cc(Cl)ccc1Cl +Cc1cc(C(=O)N2CCC(Oc3ccc(C)c(C)c3)CC2)on1 +C#CC(OC(=O)c1ccc(-n2cnnc2)cc1)C1CC1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc3c(c2)CCC3)cc1 +CC(Sc1nncn1-c1ccccc1)C(=O)Nc1ccc(F)cc1 +CCOC(=O)c1cnc(N2CCCCC2)nc1COC +Nc1nc(NC(Cn2ccnc2)c2ccccc2)c2cn[nH]c2n1 +Cc1cc(S(=O)(=O)N2CCC3(CC2)OCCO3)c(C)cc1Cl +Cc1cc(F)ccc1CCNC(=O)c1n[nH]c(=O)c2ccccc12 +N#CCCN(CCC#N)C(=O)CN1CCCc2ccccc21 +CNC(=O)C(C)Oc1ccc(F)cc1Br +CCOc1ccccc1C(=O)NCC1(O)CCOc2ccccc21 +O=C(Cc1ccc(F)cc1)NCCc1csc2ncnn12 +CS(=O)(=O)N1CCN(C(=O)c2c[nH]c3ccccc23)CC1 +COc1ccc(C(=O)N(C)CCC(F)(F)F)cc1OC(F)F +Cc1ccc(OCC(=O)NCc2ccc3c(c2)OCCO3)cc1C +COC(=O)c1c(-c2ccccc2)noc1NCc1ccc(C)o1 +CCc1ncc2c(n1)CN(C(=O)c1cnn(C(C)C)c1)C2 +CCOC(=O)c1ccc(-n2nnc3[nH]cnc3c2=O)cc1 +O=S(=O)(Nc1ccccc1OC(F)F)c1ccccc1 +O=c1[nH]c(=O)n(CCCc2ccccc2)cc1-c1ccccc1 +O=S(=O)(c1cccc(Cl)c1)N1C=CC(C(F)(F)F)=NCC1 +CCCCCn1c(C2CC(=O)N(C3CC3)C2)nc2ccccc21 +CCCN1C(=O)NC(c2ccco2)C(C(=O)OC)=C1C +COCCOc1ccc(NC(=O)NC2CC2)cn1 +CCCC(C)NC(=O)C(C)N1CCN(C(=O)N2CCOCC2)CC1 +CC(C#N)CN(C)C(=O)c1ccc(C#CCO)cn1 +O=C(CSc1ccc(F)cc1)NCC1(O)CCOCC1 +O=S(=O)(c1ccc(SCCCO)nc1)N1CCCCC1 +CC(C)(C)c1noc(C2(NC(=O)CCn3cncn3)CCCCC2)n1 +O=C(Cn1cc(C2CC2)nn1)N(Cc1ccco1)c1cccc(F)c1 +Cn1ncc2cc(C(=O)NCc3ccncc3)c(N)nc21 +O=C(CC1CCCC1)N1CCN(Cc2nnnn2C2CC2)CC1 +COc1ccc2oc(C(=O)Nc3ccc(F)cc3)cc(=O)c2c1 +Cc1nc(CCN(C)C(=O)C(c2ccccc2F)N(C)C)no1 +Cn1ncc2c1N=C(O)CC2c1cccc(OCc2ccccc2)c1 +Cc1ncccc1CN(C)Cc1nc2ccccc2n1C +O=C(CNC(=O)c1cc2ccccn2n1)NCC1CCCO1 +CC(C)Oc1cccc(C(=O)Nc2ccc(C(N)=O)cc2)c1 +CNC(=O)NC(C)(C)C(=O)Nc1cccc(F)c1F +O=C(NCc1c(-c2ccc(Cl)cc2)nc2n1CCS2)C1CC1 +Nc1nccnc1C(=O)Nc1ccn(Cc2ccccc2)n1 +Cc1cc(C)c2c(NC3CC4C(=O)N(C)CC(=O)N4C3)ncnc2n1 +CC(NS(=O)(=O)NCc1ccccc1)c1cn2ccsc2n1 +CCC(C#N)NC(=O)c1csc(-c2ccc3c(c2)OCCO3)n1 +CCCC(=O)Oc1ccc2nc3ccc(=O)cc-3oc2c1 +Cc1cc(F)cc2c(=O)c(C(=O)NCC(=O)NC(C)(C)C)c[nH]c12 +N#Cc1cc(Cl)ccc1N1CCCC(CO)C1 +CC(C(=O)N(C)Cc1ccccc1)n1nc(-c2ccccc2)ccc1=O +NC(=O)c1csc(CN2CCc3ccccc32)c1 +Cc1csc(CNC(=O)NCc2ccc(N3CCCC3=O)cc2)n1 +Cc1ccc(CN(C)Cc2cccc3c2OCCO3)s1 +CCc1cnc(NCc2c(C)nn(CC)c2C)nc1 +Cc1noc(CCCC(=O)N2CC=C(c3ccc(O)cc3)CC2)n1 +Cc1ccc(CNC(=O)C2CCn3c(nc4ccccc43)C2)o1 +CN(Cc1ccccc1)S(=O)(=O)c1ccccc1Br +CC1COC(c2ccccc2)CN1C(=O)c1cccc(-n2ccnn2)c1 +Cc1[nH]c(=O)sc1S(=O)(=O)NCCC(F)(F)F +CC(C)(NC(=O)NCc1cccc(Br)c1)C(N)=O +CC(C)(C)OC(=O)N1CCN(c2cc(O)cc(O)c2)CC1 +N#Cc1ccccc1NC(=O)CCC(C#N)c1cccnc1 +Cc1nnc(NC(=O)N2CC(Oc3ccccc3)C2)s1 +COc1ccccc1OC1CCN(C(=O)c2cccc(O)c2C)CC1 +CC(Nc1ncc(C(N)=O)cc1Cl)c1nc2ccccc2[nH]1 +O=C(Cn1nnc(-c2cccc(F)c2)n1)NCCc1cccs1 +Cc1ccc(S(=O)(=O)CC(=O)NC2CCCCC2)cc1 +Cc1cc(C(=O)Nc2ccc(N3CCOCC3)cn2)c(C)s1 +CNC(=O)NCC(=O)N(C)Cc1ccccc1N1CCCC1 +CC1(C)CCC(NC(=O)Cc2ccc[nH]2)c2ccccc21 +COC(=O)Cc1nn(-c2cccc(F)c2)c2c1nnc1nc(C)nn12 +CC(C)(C)OC(=O)NCC(=O)c1ccc(F)cc1 +CC(=O)N1CCN(c2cc(C(C)C)nc3ccnn23)CC1 +Cc1cc(-c2nn3c(-c4cc(C)n[nH]4)nnc3s2)[nH]n1 +COc1ccc(F)cc1NC(=O)CCSc1ccccn1 +COc1ccc(NS(=O)(=O)c2cc(F)ccc2F)cc1 +CCOC(=O)c1cc(S(=O)(=O)NCc2ccco2)n[nH]1 +COc1ccc(NC(=O)CSc2ccc3nncn3n2)cc1 +Cc1cccc2nnc(N3CCN(C(=O)c4ccco4)CC3)n12 +COc1ncccc1C(=O)Nc1ccc2nc(NC(C)=O)sc2c1 +O=C1OC(C(=O)N2CCCC2c2cccc(F)c2)Cc2ccccc21 +COC(=O)C(C#N)c1nc2ccccc2nc1NCCS(N)(=O)=O +CCOc1c(Cl)cc(C(=O)NCc2ccc(C#N)cc2)cc1OC +O=C(Nc1ccc2c3c(cccc13)CC2)NC1(CCO)CCOCC1 +CCCc1nnc(NC(=O)C2(C)Cc3ccccc3C(=O)O2)s1 +NC(=O)C1Cc2ccccc2CN1C(=O)c1n[nH]c2ccccc12 +Nc1cc(Br)cc2c1CCN(CCO)C2 +O=C(Nc1ccc2nccnc2c1)C1COc2ccccc2O1 +Cn1cc(Br)c(C(=O)Nc2ccn(CC#N)n2)n1 +Cc1ccc(Cl)c(NC(=O)NCc2ncc[nH]2)c1 +CC(Cc1ccccc1)NC(=O)c1ccnc(N)c1 +CC(NC(=O)N(CC1CCC1)C(C)c1ccccc1)c1nncn1C +Nc1c(Cl)ccn2c(-c3ccc(F)cc3)nnc12 +CC(=O)Nc1ccc(C(=O)Nc2ccc(C)c(Br)c2)cc1 +COc1ccc(CCc2nc3ccc(C)nc3o2)cc1OC +COCCOCC1CCN(C(=O)c2cnc3ccccc3n2)CC1 +COc1ccc(F)c(NC(=O)N2CCCC(C(=O)NCC3CC3)C2)c1 +O=C(NCCCc1nc2ccccc2[nH]1)c1cc(=O)[nH]c2ccccc12 +CC(C)(C)C(NC(=O)Cn1nnc(-c2ccccc2)n1)C(N)=O +CC(C)N(CC(N)=O)C(=O)c1cc(Cl)ccn1 +O=C(c1ccc(F)cc1F)N1CCN(c2ncnc3[nH]cnc23)CC1 +COc1ccccc1C1NCCc2ccc(F)c(OC)c21 +COc1ccccc1OCC#CCNC(=O)CC1CCCC1 +Cc1cccc(OCCC(=O)NCC(N)=O)c1C +Cc1cn2nc(NCCCOC(C)C)sc2n1 +CCOc1ccc(C(=O)N2CCN(CCC#N)CC2)c(OCC)c1 +CC(CC#N)N(C)C(=O)Nc1ccccc1OCC1CCCCO1 +COc1ccc(C(=O)CSc2ccccn2)cc1 +CCOc1ncccc1CNC(=O)Nc1cc(Cl)ccc1C +COCC1CCC2C(CCN2C(=O)c2ccc3c(c2)OCO3)O1 +CC(C)NC(=O)c1cccc(NC(=O)COc2ccc(Cl)cc2)c1 +CSc1ccccc1NC(=O)CN(C)C(=O)CCn1cncn1 +CCCCNC(=O)c1ccc(-c2ccc(C)cc2)[nH]c1=O +COc1ccc(Br)cc1S(=O)(=O)NCCC(C)C +CCS(=O)(=O)NC(C)c1ccc(C(C)C)cc1 +CNC(=O)C(C)CN(C)C(=O)c1cc(Cl)c2ccccc2c1O +Cn1cc(-c2cnc(N)nc2C2CCCN2C(=O)c2ccccc2)cn1 +CCOc1ccc(-c2noc(-c3ccc[nH]3)n2)cc1 +O=C(NCC1Cc2ccccc2O1)c1cc(Cl)ccn1 +Cc1c(C(=O)N2CCOCC2)cnn1-c1cccc(Cl)c1 +CCc1ccccc1N1CC(C(=O)Nc2ccnc(C)c2)CC1=O +Cc1ccc(NC(=O)N2CCn3c(nn(C)c3=O)C2)cc1C +CNC(=O)c1cc(NC(=O)c2cc(F)cc3[nH]cnc23)ccc1Cl +O=C(CSc1ncnc2c1oc1ccccc12)NCc1ccco1 +CCC(=O)Nc1ccc(C)c(S(=O)(=O)Nc2ccc(OC)cc2)c1 +CNC(=O)CSc1nnc(CNc2ccccc2)n1C +CC1CCCCC1NC(=O)Cn1nnc(-c2ccc(C(N)=O)cc2)n1 +COc1ccc(C(=O)Nc2cccc(-c3ccc4nncn4n3)c2)cc1 +CCCOCCNC(=O)c1c(C)noc1-c1cccs1 +CC(C)(C)OC(=O)NCCNC(=O)Nc1nc2ccccc2s1 +Cc1csc(NC(=O)c2cccc(OCC3CCCO3)c2)n1 +Cc1nn(C)c(C)c1C(C)NC(=O)NC1CCc2cc(Cl)ccc21 +CCc1ccc2ncc(C#N)c(N3CCC4(CC3)OCCO4)c2c1 +CCC(NCc1ccc(SC)cc1)C(=O)OC +O=C(NCc1ccc(COCC2CC2)cc1)c1cc2ccoc2cn1 +Cc1cc(C)cc(OC(=O)CN(C)S(=O)(=O)c2ccccc2)c1 +CC(C)(C)OC(=O)N1CCC(c2nnco2)CC1 +CCNS(=O)(=O)c1cc(N)c2[nH]c(=O)oc2c1 +O=C(Cc1ccccc1)N1CCC(c2nc(C3CCOC3)no2)CC1 +CCc1nc2n(n1)CCCC2NC(=O)CSc1ccc(C)cc1 +O=C(NCc1nnnn1C1CCCCC1)c1ccccc1F +Cc1ccc(C(C)NC(=O)NC(C)c2cc(C)sc2C)o1 +CC=CCCNC(=O)NC1CCN(c2c(F)cccc2F)C1 +COc1cc(CCNC(=O)CCc2ccccn2)ccc1C +COC(=O)c1ccc(C(=O)NC(C)c2c(C)noc2C)cn1 +O=C(c1ccc2ccccc2c1)N1CCN(C(=O)C2CCCO2)CC1 +Cc1ccc(-n2nnc(-c3cccnc3)c2N)c(C)c1 +Cc1sc(=O)n(CC(=O)N(C)CCC(C)C)c1C +N#CC(CCC(=O)Nc1cccc(Cl)c1)c1ccccn1 +CCn1cnnc1CCNC(=O)c1cc(-c2ccc(C)s2)n[nH]1 +COc1ccc(-n2ccc(CNC(=O)C3CC(=O)N(C)C3)n2)cc1 +O=C(NCC1(O)CCOc2ccccc21)C1CC=CCC1 +Cc1cccc(NC(=O)c2ccc3[nH]c(C)cc(=O)c3c2)c1 +O=C1C(n2c(=O)sc3ccccc32)CCN1CC(F)(F)F +CC(NC(=O)CN1CCN(c2ccccc2O)CC1)c1ccccc1 +CNC(=O)NCC(=O)N1CCCc2cc(C)ccc21 +COc1ccc2nc(Cn3cnc4cccc(OC)c4c3=O)[nH]c2c1 +CCOC(=O)C1CCCN(C(=O)c2cc3n(n2)CCCO3)C1 +COc1cccc(-c2cnnc(N3CCCCC3CO)n2)c1 +O=C(Nc1ccc(C(=O)Nn2cnnc2)cc1)c1ccccc1 +COc1cccc(C(=O)N2CCC3(CCCN(CC4CC4)C3=O)C2)c1 +COc1cccc2c1CCNC2C(O)c1ccc(O)cc1 +COCCCNC(=O)c1oc2c(C)ccc(C)c2c1C +O=C(NCCCNC(=O)c1ccccn1)c1cnc2ccoc2c1 +CCNC(=O)COC(=O)Cc1ccc(-c2ccccc2)cc1 +CC1(C)CN(Cc2csc(Cc3ccccc3)n2)CCO1 +Cc1c(C(=O)OCc2nc(N)nc(N)n2)sc2ccccc12 +CS(=O)(=O)N(CC(=O)Nc1cccnc1)c1cccc(Cl)c1 +Cc1ccc(NC(=O)CCCCNC(N)=O)cc1Cl +COc1cc(C#N)ccc1OCC(=O)N(C(C)C)C(C)C +Cc1nc(-c2nc(C3CCCC3)nn2CCO)cs1 +CCC1(O)C(=O)OCc2c1cc1n(c2=O)CCC1=O +NS(=O)(=O)c1ccc(CNS(=O)(=O)c2ccccc2)cc1 +Cc1noc(C)c1CC(=O)NC1CCSc2c(F)cccc21 +Nc1nc(CCC(=O)NC2CC(=O)N(C3CCCCCC3)C2)n[nH]1 +CNC(=O)NCC(=O)NCC(C)N1CCN(c2ccccc2)CC1 +O=C(CNC(=O)Nc1ccncc1)NCC(F)(F)F +Cc1cc(S(C)(=O)=O)ccc1NC(=O)CCc1ccc(C#N)cc1 +CCCS(=O)(=O)c1ccc(NCC2CC2)cc1 +COCCN1CCN(CC(F)(F)F)CC1(C)C +Cc1c(N)ccc2nnc(Cc3ccc(Cl)cc3)n12 +COc1ccccc1C(=O)NCCNc1cc(-n2cccc2)ncn1 +Cc1cccc(OCC(O)CNC(=O)c2cccc3cccnc23)c1 +Cc1cccc(OCCNC(=O)C2(C#N)CCCC2)c1 +CCCCNC(=O)CN1C(=O)C(C)(C)Oc2cc(O)ccc21 +CCC(=O)N1CCc2ccc(NC(=O)c3ccc(F)cc3)cc2C1 +CC(O)c1nc2cccc(F)c2n1C1(c2ccccc2)CC1 +Cc1ccc(S(=O)(=O)Cc2cccc(C(N)=O)c2)cc1 +Cc1cc(C(=O)N2CCN(C(=O)CO)CC2)sc1C +CC(C)Nc1nnc(SCc2ccc(C#N)cc2)s1 +CC(C)(CCC(=O)NCC1CN2CCCCC2CO1)c1ccccc1 +Cc1ccccc1-n1nnc(C(=O)OC(C)C)c1N +CC(C)n1ncc(NC(=O)Cn2cnc(-c3ccccc3)c2)n1 +Cc1ccc(S(=O)(=O)NCCC(=O)NCC(C)O)cc1C +CC(C)Oc1ccc(S(=O)(=O)Nc2cnn(CC(F)F)c2)cc1 +CCC(CC1CCCCC1)C(=O)N1CCN(C(=O)COC)CC1 +O=C(Nc1cnn(-c2ccccc2F)c1)C1CCCCC1 +CC(=O)Nc1ccc(F)c(NCc2cccn2C)c1 +N#Cc1cccc(CNCCc2cccc(C(N)=O)c2)c1 +CC(=O)NCCC(=O)Nc1ccc(-c2cc[nH]n2)cc1 +Cc1nccn1-c1cccc(C2CCN(C(=O)C3CCCC3)CC2)n1 +Cc1c(C(=O)Nc2ccc3c(c2)COC3)cnn1C1CCCC1 +Cc1cccnc1NC(=O)C1CC(=O)Nc2cc(F)ccc21 +O=C(Nc1cc(-c2ccncc2)n[nH]1)c1cncc(Br)c1 +Cc1cccn2c(=O)cc(OCc3nc4ccccc4c(=O)[nH]3)nc12 +Cn1cc(C(=O)N(Cc2ccccc2)C2CC2)ccc1=O +CCC(=O)Nc1ccccc1C(=O)OCC(=O)c1ccccc1 +O=C1CN(C(=O)COc2ccccc2Cl)CCN1 +O=C(CCS(=O)(=O)c1ccccc1F)Nc1ccc2c(c1)CCC2 +O=C(Cc1cc(=O)[nH]c(=O)[nH]1)NC1CCC(O)CC1 +Cc1ccc(NC(=O)Cn2cc(N)ccc2=O)cc1C +CS(=O)(=O)c1ccc(CCNc2ccc(Cl)c(C#N)n2)cc1 +O=c1c(C(F)(F)F)cccn1Cc1coc(-c2cccc(F)c2)n1 +Cc1cccc(C)c1CN(CCC#N)C1CCOCC1 +CN(Cc1ccccc1F)C(=O)Cc1csc(-c2ccoc2)n1 +CCC1(C)C(C#N)(C(=O)OC)C1(C#N)C(=O)OC +CCN(C(=O)c1ccc(OC)nn1)C(C)c1ccc(F)cc1 +Cc1cc(C(=O)Nc2ccccc2)c2cnn(C(C)C)c2n1 +CCn1c(-c2ccc(Cl)cc2Cl)ccc(CO)c1=O +CNC(=O)CNC(=O)c1ccc(N(C)C)c(F)c1 +CC1CN(C(=O)c2c[nH]c3ccc(Br)cc23)CCO1 +CC(C)C(C)NC(=O)CN1CCOc2ccccc21 +Cc1nn(C)c(C)c1NC(=O)c1cc2ccccc2s1 +Cc1ccccc1COC1CCN(C(=O)c2cnccn2)CC1 +CCOC(C)C(=O)NC1CCN(C(=O)c2ccncc2)CC1 +COC(=O)CCCn1ncc2c1CCC(OC)C2 +CSc1ccc(S(=O)(=O)Nc2c(C)cc(C)nc2C)cc1 +CCn1c(CN2CCCC2Cn2cncn2)nc2c(F)cccc21 +COCCOC(=O)c1sc2ccc(F)cc2c1C +Fc1cc(F)cc(CNc2cnn(CC(F)F)c2)c1 +O=c1[nH]c(NCCCOCC2CCOC2)nc2ccccc12 +Cn1nccc1CNC(=O)NC1(c2cccc(Br)c2)CC1 +O=C(Nc1ccccc1Sc1ccccc1)c1cnccn1 +CCOc1cc(C2CC(=O)Nc3cc(C)c(C)cc32)ccc1O +CCC(=O)NCC(=O)NCc1cccc(OC(C)C)c1 +CCC(CO)NC(=O)Nc1cc(OC)cc(OC)c1 +Cc1cc(C(=O)Nc2ccc3nc(-c4ccco4)[nH]c3c2)n[nH]1 +O=C(Cn1nc(N2CCOCC2)ccc1=O)NCCc1ccccc1 +O=C(NCCc1nccs1)c1ccc(Cl)cc1 +COC(=O)c1c[nH]c(-c2ccc3c(c2)OCCO3)n1 +CC1(C)C(NC(=O)c2cc3c(s2)CCC3)C2CCOC21 +Cc1noc(C)c1C(=O)N1CCOC2CCCCC21 +COc1ccccc1CC(C)N(C)C(=O)c1ncoc1-c1ccco1 +Cc1cc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)no1 +Cc1noc(CCC(=O)Nc2cnn(CC(=O)N3CCCCC3)c2)n1 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C1CCOC1=O +CCOCCn1c(=O)[nH]c2cc(C(=O)N3CCC(OC)CC3)ccc21 +CC(NCC(F)(F)F)(C(N)=O)c1cccc(OC(F)F)c1 +OCc1c(-c2ccccn2)nc2sc(-c3ccc(F)cc3)nn12 +CCCC1CCC(NC(=O)Cn2ccc(=O)[nH]c2=O)CC1 +c1ccc(-c2nccc(NC3CCCN(c4cccnn4)C3)n2)cc1 +O=C(NCCc1ccco1)NCc1nc2ccccc2s1 +Cc1nn(-c2ccc(F)cc2F)c(C)c1C(=O)Nc1cn[nH]c1 +CCc1nn(C)c(CC)c1CN1CCOCC1c1ccc(C)o1 +CCCC1=C(C(=O)OCC)C(c2ccc(F)c(F)c2)n2nnnc2N1 +Cc1cc(C)n(C2CCCN(C(=O)c3cc(-c4ccco4)on3)C2)n1 +CC(C)(CNc1ncnc2cccc(F)c12)N1CCOCC1 +Cc1cc(Br)ccc1NCc1ccc(C(N)=O)cc1F +CN(C)c1nc(C2CCN(C(=O)C3CC3)C2)cc(=O)[nH]1 +CCCC(=O)N1CCN(S(=O)(=O)N2CCN(C)CC2)CC1 +Cc1ccc(C)c(OCC(=O)NCC(F)(F)F)c1 +CC1CCC(N(C(=O)COc2ccc(CC(N)=O)cc2)C2CC2)CC1 +COc1ccc(C#CCNC(=O)c2ccc(F)cc2)cc1 +COCCn1cnnc1SCC(=O)c1ccc2c(c1)CCCC2 +COCCN1CC2(CCCN(C(=O)c3ccc(N)nc3)C2)CCC1=O +CN(C)C(=O)N1CCN(C(=O)c2cccnc2OCC(F)F)CC1 +COC(=O)C(NC(=O)c1cc(SC)ccc1Cl)C(C)C +Cc1cc(C(=O)NC(C)C2CC2)c2c(C)nn(C)c2n1 +Cc1cc(NC(=O)c2ncoc2C(C)C)n(-c2ccncc2)n1 +Cc1sc2nc(SC(C)C(N)=O)n(C(C)C)c(=O)c2c1C +Cc1cc(NS(=O)(=O)c2cn[nH]c2C)n(C)n1 +Cc1ccc(C2(O)CCN(C(=O)c3cnccn3)CC2)nc1 +Cc1nc(CC(=O)NC(C)c2ccc3ccccc3c2)cs1 +CC(=O)c1ccc(F)c(N2CCC(n3cccn3)CC2)c1 +Cc1ccc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)s1 +CCc1ccc2occ(CC(=O)Nc3ccncc3)c2c1 +O=C(CCc1nc2ccccc2s1)N=c1[nH]c2ccccc2[nH]1 +CC(Nc1ccnc(C(N)=O)c1)c1cccc(Br)c1 +Cc1ccc(NC(=O)Nc2ccn(C)n2)cc1OCC(F)F +CCC(CO)NC(=O)c1cc(OC)c(OC)c(OC)c1 +CN1CC(C(=O)NCc2ccnc(-n3cccn3)c2)CC1=O +CCc1ccc(C2COCCN2S(=O)(=O)c2ccc(C)s2)o1 +COc1ccc2c(C(=O)Nc3ccc(C)c(F)c3)cc(=O)oc2c1 +CC(C)(CNC(=O)c1ccc2c(c1)NC(=O)CS2)N1CCOCC1 +Cc1ccc(S(=O)(=O)N(C)C)cc1NCc1ccc(C#N)cc1 +Cc1cc(CN2CCN(C(=O)c3c(C)nn(C)c3C)CC2)no1 +CCn1nc(C)cc1C(=O)Nc1ccc(-n2cnnn2)cc1 +O=C(NCCN1CCOCC1)c1cc(-c2ccc(F)cc2)on1 +COc1ccc(Cl)cc1NC(=O)CN(C)C(=O)c1cccnc1 +Cc1ccc(NC(=O)c2sc(Cc3ccccc3)nc2C)nc1 +CCCCNC(=O)C1CCN(c2ccc(CC)cc2)C1=O +O=C(c1cn2cccnc2n1)N1CCC(c2c[nH]c3ccccc23)CC1 +CCOc1ncccc1NC(=O)CCc1ccccc1 +CCc1onc(C)c1NC(=O)N(C)Cc1ccsc1 +O=c1[nH]c2cc(NS(=O)(=O)c3ccc(Cl)cc3)ccc2o1 +Cc1ccc(-c2nc3cc4c(cc3n2CCCO)OCCO4)cc1N +CCCNc1cccc(C(=O)Nc2nc(C)cs2)n1 +O=C(COC(=O)Cn1cnc2ccccc21)Nc1ccc(F)cc1F +Cc1ccc(C(=O)NCCOc2ccccc2)cc1 +CCCOc1ccc(CNC(=O)c2ccc(C#N)cc2)cc1 +COc1ccc(N2CCCC(C(=O)NC(C)c3ccccc3)C2)nn1 +CCCCCOCC(=O)Nc1ccc2c(c1)COC2 +Cc1ccc(NCCNC(=O)Nc2cccc(C(F)(F)F)c2)nn1 +Cn1cc(S(=O)(=O)N2CCC(NC(=O)C3CCCC3)CC2)cn1 +O=C(CN1CCN(c2ccc(O)cc2)CC1)NCc1ccccc1 +CCC(=O)N1CC2=C(C1)C1CN(CC3CC3)S(=O)(=O)C1CC2 +O=C(NCCc1nc2ccccc2s1)c1ccc(F)cc1F +Cc1ncc(CNc2ccc(Nc3ccccc3)nc2)cn1 +COC(=O)c1ccc(C2CCc3nc(N)nn3C2)cc1 +COc1cccc(NC(=O)Cn2cc(-c3nc(C)no3)ccc2=O)c1 +O=C(CNS(=O)(=O)c1c(F)cccc1F)OCc1ccccc1 +COc1ccc(C(=O)Nc2ccc(C)cn2)c(OC)c1 +CN(CCCNS(=O)(=O)c1ccc(C#N)cc1)c1ccccc1 +COC(=O)c1cc(F)c(C)c(NCc2noc(-c3ccoc3)n2)c1 +Cn1cnnc1SCC(=O)NCc1ccnc(OC2CCC2)c1 +COc1ccc(N2Cc3nc(=O)n(CCC(C)C)n3C2=O)cc1 +CN(C)c1ccc(C(=O)NCC2(O)CCOc3ccccc32)cc1 +CCCCC(O)c1cc(C)cc2c1OCCC2NC(=O)CC +O=c1c(NCc2ccco2)c(-c2ccccc2)c1=O +CN(C)c1ncnc2c1CCN(C(=O)c1ccc(Cl)cc1O)C2 +CC1(OC(=O)c2ccccc2)C2C=CC1C1C(=O)NC12 +O=C(Cn1ncc2ccccc21)Nc1ccnn1CC1CCOC1 +COCCCS(=O)(=O)N1CCc2ccc(Cl)cc2C1 +Cc1occc1C(=O)N1CCCN(C(=O)c2ccc(Cl)cc2)CC1 +CC1CCCC(CNC(=O)NCc2nnc3ccccn23)C1 +O=C(CC1CCC(C(F)(F)F)CC1)N1CCCC(c2cn[nH]c2)C1 +CCS(=O)(=O)N1CCCCCC1c1ccco1 +CCN(CC)c1nc2sc(C(=O)NC(C)C(=O)NC)cc2s1 +COCC(C)NC(=O)Cc1c(C)nc(-c2ccccn2)[nH]c1=O +Cc1cc(C)nc(SCC(=O)NC(C)Cc2ccccc2F)n1 +O=C(CCC(=O)c1cccs1)NCc1ccccn1 +CCN(CC)C(=O)CNc1ccc(Cl)cc1C(N)=O +CC(C)c1csc2nc(-c3ccnc(S(C)(=O)=O)c3)[nH]c(=O)c12 +CCOC(=O)N1CCC(NC(C#N)c2ccccc2)CC1 +CCc1nc2n(n1)CCCC2NC(=O)c1ccc(C)cc1C +Cc1ccc(C(=O)OCC(=O)Nc2ccc(C)c(F)c2)cn1 +Cc1cccc(CNC(=O)c2cn3cccnc3n2)c1 +CCCN(C(=O)c1ccccc1NC(=O)C1=C(C)OCCC1)C(C)C +Cn1ccc2ccn(CCOCC(F)(F)F)c(=O)c21 +CCOC(=O)CCCn1cc(C(F)(F)F)ccc1=O +Cc1ncc(CN2CCN(Cc3cccs3)CC2)s1 +CCCc1nc2cc3c(cc2n1CC#N)OCCO3 +COCC(C)NC(=O)NC(C(N)=O)c1ccccc1 +NC(=O)C1=C(N)Oc2[nH]c(=O)[nH]c(=O)c2C1c1cccnc1 +O=C(c1cnn(-c2ccccc2)n1)N1CCCC(C(F)(F)F)C1 +COCC(=O)Nc1cccc(COc2ccc(CC#N)cc2)c1 +OCc1nnn(CCOc2ccc(Cl)cc2)c1C1CC1 +CCCCc1nnc2sc(COc3ccc(OC)cc3)nn12 +COc1ccc(-c2csc(-c3ccncc3)n2)cc1F +COCc1noc(Cn2ccc3ccc(C(=O)OC)cc3c2=O)n1 +CC(CO)NC(=O)COc1ccc(C(=O)c2ccc(Cl)cc2)cc1 +CC(C)N(Cc1cccs1)c1ncc(Br)cc1N +CCOc1cc(S(=O)(=O)NCc2cccnc2)c(C)cc1C +CCCn1nc(C(=O)Nc2sc(CC)cc2C#N)ccc1=O +Cc1nc(C)n(CC2CN(Cc3cscn3)CCO2)n1 +Cc1cc(F)ccc1CNC(=O)c1nonc1N +Cc1nnc(CN2CCCc3cc(Cl)ccc32)o1 +Cc1cc(C(=O)Nc2nc3c(s2)CC(C)CC3)on1 +CC(=O)Nc1ccc(S(=O)(=O)c2ccc(C)cc2)cc1 +O=C1CCOc2c(Br)cc(F)cc2N1 +NC(=O)CNC(=O)Cc1csc(-c2cccc(C(F)(F)F)c2)n1 +O=S(=O)(Nc1ccc2c(c1)CCC2)c1ccc(F)cc1 +Cc1[nH]c2c(c1C(=O)N1CCn3cncc3C1)C(=O)CCC2 +COc1cccc(-c2noc(N)c2-c2cccs2)c1 +O=C(Nc1nccs1)c1nnsc1-c1ccccc1 +O=C(C1CCN(c2ccc3cccc(O)c3n2)CC1)N1CCCC1 +NS(=O)(=O)CCSc1nnc(Nc2ccccc2F)s1 +CCOc1ccccc1C(=O)NCC(=O)N(C)C1CC1 +Cc1ccc(C(C)NC(=O)Cc2c[nH]c3ncccc23)c(C)c1 +COc1c(C)cnc(CNC(=O)Nc2nc(C)c(C)o2)c1C +N#CC1(NC(=O)CSc2ccc(F)cc2F)CCCC1 +Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(CO)C(O)C1 +CN(C)C(=O)Cn1nc2c3ccccc3nc(C3CC3)n2c1=O +Cc1noc(C)c1C(C)C(=O)Nc1ccc(F)c(F)c1 +CC(Oc1cccc2ccc(=O)[nH]c12)C(=O)Nc1ccc(Cl)cc1 +CCC(CCO)NC(=O)Nc1cccc(CN(C)C(C)=O)c1 +C=CCn1c(SCC(=O)NC2(C#N)CCCCC2)nnc1C1CC1 +Cc1cc(NC(=O)NC(C)C(=O)N2CCCC2)no1 +CCOC(=O)c1nn(-c2ccccc2F)c(C)c1C(C)=O +CC(=O)N1CCc2cc(C(=O)NCC3CCC(C)CC3)ccc21 +CCn1cnnc1CNS(=O)(=O)c1c(C)sc2ccccc12 +O=S(=O)(C1CC1)N1CCc2c(CNc3nccs3)n[nH]c2C1 +CCC(CO)NC(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +COCC(NC(=O)Cc1ccc(F)cc1F)c1ccco1 +COCCNC(=O)CC1c2ncccc2C(=O)N1c1ccccc1 +Cc1cccc(CN2CCCCC2C(=O)OCc2nnc(C)o2)c1 +CN(Cc1nc2ccccc2n1C)C(=O)CCc1cscn1 +CCN(CC)S(=O)(=O)CC(=O)N1CCc2ccccc2CC1 +COCC(=O)N1CCN(S(=O)(=O)c2cccc(Cl)c2)CC1 +COC(=O)NCC(=O)N1CC=C(c2ccccc2)CC1 +Cc1ccc(C(=O)CCC(=O)Nc2ccc3c(c2)OCO3)s1 +O=S(=O)(NCCc1ccc2c(c1)OCO2)c1ccc(F)cc1 +Cc1nc2sccc2c(=O)n1NC(=O)c1ccco1 +CC(C)C1COC2(CCCN(C(=O)c3ccncc3)C2)C1 +O=C(CSc1nc(C=Cc2cccs2)n[nH]1)N1CCCCC1 +Cc1cccn(C(C(=O)Nc2ccc(C#N)cc2)C(C)C)c1=O +CCn1nc(C(=O)NCc2c(C)nn(C)c2C)c(=O)c2ccccc21 +O=C(Cn1nc(-c2ccc(F)cc2)ccc1=O)N1CCCCC1 +O=C(NCCc1nccs1)c1ccc(Cl)cc1O +Cc1cc(C(C)NC(=O)c2cc(Cl)c[nH]2)c(C)s1 +Cc1cc(C(=O)Nc2ccccc2F)cc(S(N)(=O)=O)c1C +COc1ccc(C(=O)Nc2ncccc2C)cc1Br +Cc1ccc(CC(=O)N2CCN(Cc3ccc(C#N)cc3)CC2)cc1 +CCC(C)NC(=O)C1(C)CCC(=O)N1Cc1ccc(OC)cc1OC +COC(=O)Cn1cc(NC(=O)c2csnn2)cn1 +CCN(CC)c1ncnc(Oc2ccc(OC)cc2)c1N +Cc1ccc(C(C)NC(=O)CN(C)S(C)(=O)=O)cc1F +O=C(c1ccc(S(=O)(=O)NCc2ccncc2)cc1)C1CC1 +CC(C)(C)c1ncc(CNc2ccc(OCCO)nc2)s1 +CC1=Nc2nnnn2C(c2cccc(F)c2)C1C(N)=O +CNC(=O)c1cccc(COc2cccc(CO)c2)c1 +CCc1nc(CNC(=O)c2ccc(-c3cscn3)cc2)cs1 +CC(C)(C(=O)N1CCCC(n2cncn2)C1)c1cccc(C#N)c1 +CC(C)N1CCOCC2(CN(Cc3nccs3)CCO2)C1 +CCN(CC)C(=O)c1cnc(C2CCCCN2C(=O)COC)nc1C +Cc1cc(C)cc(OCCN(C)C(=O)c2ccncc2)c1 +CC1CN(C(=O)c2ccc(CO)cc2)CC1(O)C1CC1 +CCc1cccc(C)c1NC(=O)Cn1nnc(-c2ccc(C)cc2)n1 +COCc1nc2ncc3c(=O)n(C4CCCC(C)C4C)ccc3n2n1 +CCc1noc(C)c1C(=O)OC(C)C(=O)Nc1ccc(Cl)cc1 +CC1CN(S(=O)(=O)NCc2cn[nH]c2)CC(C)O1 +Cc1cc(C)c(CNC(=O)C(C)n2cncn2)c(=O)[nH]1 +CC(CC#N)N(C)C(=O)Nc1ccc(SC(F)F)cc1 +CCCC(=O)Nc1cc(OCC)c(OCC)cc1N +c1cncc(COC2C3CCC2N(Cc2nccs2)CCO3)c1 +Cc1cccc(C(C)C)c1NC(=O)CSc1ccccn1 +CNS(=O)(=O)Cc1ccc(CNc2cn[nH]c(=O)c2Cl)cc1 +COc1ccc(CNC(=O)CSc2ncn[nH]2)cc1 +Cc1n[nH]c(NC(c2ccccc2)c2ccccc2)nc1=O +CC(CCc1ccco1)Nc1ncnc2c1cnn2CCO +CCC1CN2CCCC2CN1S(=O)(=O)CC1CCCO1 +CSc1nnc(SCc2nc(CCC(C)C)no2)s1 +COC(=O)CCCN1CCN(S(C)(=O)=O)CC1 +CCNC(=O)c1csc(COc2cc(Cl)ccc2Cl)n1 +COCCCn1c(C(C)(C)C)ccc(CC#N)c1=O +O=C(Nc1cccnc1)N1CCCC(C(F)(F)F)C1 +CC(=O)Nc1cc(Br)cnc1NC(C)=O +Nc1ccc(Cl)c(Nc2ncnc3[nH]cnc23)c1 +CCOC(=O)Cn1c(=O)cc(C)n(-c2ccc(OC)cc2)c1=O +Cc1noc(CSc2nnc(N3CCOCC3)s2)n1 +CC(C)(CNC(=O)COc1cccc(C#N)c1)N1CCOCC1 +CCc1nc2ccccc2n1CC(=O)Nc1ccc(C)cc1F +O=C(Cn1c(=O)oc2ccccc21)Nc1nnc(-c2ccsc2)o1 +CCN(CC)C(=O)CN(C)C(=O)C(C)Sc1ccc(Cl)cc1 +Cc1ccc(S(=O)(=O)NCCc2cccs2)c(N)c1 +COc1ccc(OC(C)C(=O)N2CCCC(c3nc(C)no3)C2)cc1 +O=C(CCn1cnc2ccccc21)Nc1ccc2c(c1)COC2 +Cc1cccc(NC(=O)Nc2cccc(Cn3cccnc3=O)c2)c1C +Cc1ccc(S(=O)(=O)Oc2ccc(NC(=O)C3CC3)cc2)cc1 +CCOc1cccc(CC(CO)c2ccccc2OC)c1 +CN(Cc1ccccn1)C(=O)Cn1c(=O)[nH]c2ccccc21 +CC(C)CC(C)N(C)C(=O)NCc1cccnc1-n1cncn1 +COc1ccc(C(N)=O)c(OCc2cccc(F)c2F)c1 +C=CCN(C)C(=O)c1ccccc1N1CCOCC1 +COc1ccc(C)cc1CCNC(=O)c1cc(OC)c(OC)cc1C +O=C(c1cnccn1)N1CCN2C(=O)N(C3CCOCC3)CC2C1 +CC(C)CC1COCCN1CC(=O)N(C)C(C)c1ccc(F)cc1 +OCCc1csc(Cc2cccc(Cl)c2)n1 +CCCC(=O)N1CCN(c2ccc(Cl)cc2NC(=O)CC)CC1 +CC(C)C(=O)NCCNC(=O)c1nn(C(C)C)c(=O)c2ccccc12 +CSc1nccn1CC(=O)Nc1ccc(F)cc1 +CN(CC1CCCC1)C(=O)c1cc(Cl)ccc1-n1cnnn1 +CC(C)(C)CC(=O)NCC(=O)Nc1ccc2c(c1)OCCCO2 +CC(C)n1cnc2cc(CNC(=O)c3cccnc3)ccc21 +CCOC(=O)CN(C(C)C)S(=O)(=O)N1CCCCC1 +CC(NC(=O)Cn1cnnn1)c1ccc(OC(F)F)cc1 +O=S(=O)(NC1CC1)c1ccccc1N1CC(O)C1 +CCC(C)C(NC(=O)c1cc(F)ccc1Br)C(N)=O +Cn1nc(C(=O)N2CCc3ccccc32)ccc1=O +O=C(c1n[nH]c2ccccc12)N1CCCCC1Cn1cccn1 +N#CCCN(CC(=O)Nc1nccs1)Cc1ccco1 +COc1ccccc1NC(=O)CNc1ccccc1 +NC(=O)CSc1nnc(SCc2cccc(F)c2)s1 +CCC(C)(C)NC(=O)c1ccc(OCC2CCCO2)cc1 +Cc1nccc(NC(=O)N(C)C(C)c2cccs2)n1 +Cc1cc(C2CCCN(C(=O)c3ccc(OCC4CC4)cc3)C2)n[nH]1 +CC(OC(=O)c1ccc2c(c1)OCCO2)C(=O)Nc1ccccc1F +COc1ccc(-c2nnc(COc3ccccc3-n3ccnc3)o2)cc1 +CCn1cc(NC(=O)N2CCC(OCC(C)C)CC2)cn1 +C=CCNC(=O)c1ccc(NC(=O)NCCC(=O)N(C)C)cc1 +COc1ccc(C(=O)Nc2nnc(-c3ccno3)o2)cc1 +O=C(Cc1ccc2c(c1)OCCO2)c1ccc(O)cc1O +CC(C1CC1)n1ncc2cc(Br)cnc21 +CCC(=O)Nc1cccc(NC(=O)c2cn(C)nc2C(C)(C)C)c1 +CCc1nc(CS(=O)(=O)c2ccc(Cl)cn2)no1 +CCc1ccccc1CNC(=O)N(C)Cc1c(C)noc1C +CC(=O)N1CCN(C(=O)c2ccc(OCC(F)(F)F)nc2)CC1 +CC(CCc1ccco1)NC(=O)Cc1c[nH]c2ccccc12 +CC1CN(C(=O)CSc2nncs2)C(C)CO1 +CNC(=O)NCC(=O)N1CCC(Oc2cc(C)ccc2C)CC1 +CCSc1nnc(CC(c2ccc(F)cc2)c2ccco2)o1 +CC(=O)N(C)Cc1ccccc1NC(=O)C1CC=CCC1 +CCOC(=O)CC1NCCc2cccc(OCC)c21 +CC(C)OCCC(=O)N(Cc1nc2ccccc2c(=O)[nH]1)C(C)C +COC(=O)Nc1cccc(NCC(=O)N(C)C2(C#N)CCCCC2)c1 +CC(C)NC(=O)C1CCC(CNC(=O)c2cnn3c2OCCC3)CC1 +Cc1nc(COC2CN(Cc3ccccn3)C3CCCOC23)cs1 +Cc1cc(NC(=O)CCC(=O)Nc2nccs2)c2ncccc2c1 +COc1cc2nc(-c3ccc(Cl)cc3)oc(=O)c2cc1OC +COC(=O)C1(N(C)C(=O)c2cccc3ncccc23)CCCCC1 +O=C(Nc1cccc(C(F)(F)F)c1)c1ccc(-n2cnnn2)cc1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1cccc(Cl)c1 +O=C(NCc1ccc(COc2ccccc2)cc1)NC1CC1 +O=C1CC(c2ccccc2)N(Cc2cc(Cl)ccc2F)CCN1 +c1cc2ccc(-c3nc(C4CCOC4)no3)cc2[nH]1 +CCc1ccccc1NC(=O)CN1CCOc2ccc(N)cc21 +Cc1cccnc1CNC(=O)NCc1nnc(-c2ccccc2)s1 +CC(=O)Nc1nc2c(C)cc(NC(=O)c3ccccc3C)cc2s1 +NC(=O)C1Cc2ccccc2CN1C(=O)C1C2CC3CC(C2)CC1C3 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccnn1C +Cn1cc(C(=O)Nc2cccc(-c3ncc[nH]3)c2)c(-c2cccs2)n1 +CCOc1ccc(NC(=O)COc2ccc3c(c2)CCC3)cc1OC +O=C(CCc1nc(-c2ccc3cc[nH]c3c2)no1)Nc1nncs1 +CC(C)COC(=O)N1CCN(Cc2cnc3ccc(C#N)cn23)CC1 +CCCCOc1cccc(-c2ncc(C(N)=O)c(N)n2)c1 +Cn1ccnc1SCC(=O)Nc1cnn(C(C)(C)C)c1 +Cc1nnc(NC(=O)c2c[nH]c3ccccc3c2=O)s1 +Cc1ccc(S(=O)(=O)CCN2CCOC2=O)cc1C +CC1CCC(NC(=O)NC(C)c2cccc(N3CCOC3=O)c2)CC1 +Cc1csc(=O)n1CCC(=O)Nc1cccc2cnccc12 +CC(O)CC(C)(C)CNC(=O)C#Cc1ccccc1 +CCCOc1ccc(C2C(C(=O)OC)=C(C)Nc3ncnn32)cc1 +COCC(c1ccccn1)N(C)C(=O)c1cc(=O)n(C)c(=O)n1C +CCc1ccc(C2COCCN2Cc2ccsc2)o1 +Cc1ccc(-n2ncc(C)c2N)cc1Br +CS(=O)(=O)c1ccc(CC(=O)Nc2nccs2)cc1 +COC(=O)C(N)Cc1ccc(O)cc1C(F)(F)F +O=C(Cn1ccccc1=O)Nc1ccc(Br)cc1F +COc1cccc(C(=O)NC2c3ccccc3CC2C)c1 +COc1ccc(NC(=O)Nc2snc3c2CCC3)cc1 +Fc1cnc2oc(-c3ccc(F)c(F)c3)nc2c1 +COC(=O)CNC(=O)c1cc(-c2ccccc2Cl)nn1C +CC(c1cccnc1)N(C)Cc1cnc(N2CCCC2)nc1 +CC(C)(C)OC(=O)Nc1ccc(C(=O)NCc2cccnc2)cc1 +Cc1sc2nc(Cc3ccccc3)n3nnnc3c2c1C +COc1ccc(NC(=O)c2cccc(NC(C)=O)c2)c(N)c1 +CCNC(=O)Cc1noc2c(N)cc(Br)cc12 +O=C(c1ccc2c(c1)CCO2)N1CCC(Oc2cccc(Cl)c2)C1 +Cc1ccc(C)c(N2C(N)=NC(N)=NC23CCCCC3)c1 +Cc1noc(CN2CCN(CCOc3ccc(Cl)cc3)CC2)n1 +COC(=O)C1CCc2c(cnn2CC(F)(F)F)C1 +CC(C)C(NC(=O)NCc1ccccc1CO)c1nc(C2CC2)no1 +COc1ccc(Cl)cc1NCCC(=O)N(C)CC(C)C#N +Cc1nc2ccccc2n1CCNC(=O)N(C)CCc1ccccn1 +COc1ccc2nc(OC3CN(C(=O)c4ccsc4)C3)sc2c1 +COc1cccc(C(N)=O)c1OCC(=O)NCc1ccco1 +COc1cc2c(c(Cl)c1O)C(c1cncnc1)NCC2 +O=C(CCCN1CCOC1=O)Nc1nc(C2CC2)cs1 +N#Cc1cccc(CNC(=O)NC(c2ccccc2)c2ccncc2)c1 +COc1cccc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c1O +CN(C)C(=O)N1CCC(c2nc(-c3ccccc3)no2)CC1 +CC(CO)NC(=O)c1ccccc1C(=O)c1ccc(F)cc1 +COc1ccccc1NC(=O)Cn1cc(-c2ccc(F)cc2)oc1=O +Cc1cc(C)n2cc(CSc3nc4ccccc4o3)nc2n1 +O=C(Nc1cnc2ccccc2c1)c1ccc2c(c1)C(=O)CCCO2 +CC(=O)c1ccc(C)n(CC(=O)Nc2ccc(C)cc2)c1=O +CSc1ncccc1C(=O)NCCc1ccc(F)cc1 +NC(=O)C1(CNC(=O)c2c[nH]nc2-c2ccccc2F)CCOCC1 +CCNC(=O)CN1CCN(CC(O)c2ccc(Cl)cc2)CC1 +Nc1cc(Cl)ccc1NC(=O)Cn1cncn1 +Cc1cnn(CC(=O)N2CCN(Cc3c(C)noc3C)CC2)c1 +CC(c1cccs1)N(C)c1ccc(F)cc1CO +COc1ccc(C(=O)N(Cc2ccc(F)cc2)C2CC2)c(OC)c1 +CC1CN(C(=O)c2ccnnc2)CC12CCN(c1ccsc1)C2=O +Cn1cc(NC(=O)c2cccc(C(=O)OC(C)(C)C)c2)cn1 +NC(=O)NCC(=O)NCc1ccc(CN2CCc3ccccc32)cc1 +CC(NC(=O)c1cc(COc2ccccc2)[nH]n1)c1ccncn1 +Cc1ccoc1C(=O)Nc1cccc(CNC(=O)OC(C)(C)C)c1 +CN(C)c1ncccc1N(C)C(=O)c1cccc(OC(F)(F)F)c1 +O=C(NCc1ccnc(-n2cccn2)c1)N1CCC1c1ccccc1 +Cc1sc(C(N)=O)cc1S(=O)(=O)N1CCCc2ccccc21 +CCn1cc(CC(=O)NCCn2ccc(C)n2)c2ccccc21 +CN(CCC#N)C(=O)CC(c1ccccc1)c1ccccc1 +CC(=O)Nc1ccc(NC(C)C(=O)Nc2ccc3c(c2)CCC3)cc1 +CNC(=O)c1cccc(NC(=O)Cc2cc(C)ccc2OC)c1 +CC(NC(=O)C(C(C)C)N1CCCC1=O)c1ccc2c(c1)OCCO2 +CN(CCC1CCOCC1)C(=O)c1coc(COc2ccccc2)n1 +Cc1cc(C)c(S(=O)(=O)N(C)CCCO)c(C)c1 +COc1cccc(S(=O)(=O)CCN2CCCC2Cn2cccn2)c1 +Cc1nc(C)c(C(=O)Nc2ccnc3ncnn23)s1 +CCc1ccccc1NC1CCCc2c1cnn2C +O=c1c2cccc(F)c2ncn1Cc1ccc2nonc2c1 +NC(=O)C1CCCN(C(=O)CCc2ccc(-c3ccccc3)o2)C1 +Cc1cnc(N2CC3CCCC(C2)C3OCC(=O)N(C)C)nc1 +CSc1ccccc1NCC(=O)Nc1ccccc1 +Cc1nc(C)c(CC(=O)N(C)C(C)c2ccccc2)c(=O)[nH]1 +N#Cc1ccccc1NC(=O)CNc1ccccc1F +O=c1[nH]cnc2c1nc1c(Br)cc(Cl)cn12 +Cc1cc(C)c(NS(=O)(=O)c2ccc(O)cc2)c(C)c1 +Cc1cnc(C(=O)OCC(=O)Nc2ccc(C#N)cc2)cn1 +CSc1cc(-c2nc(-c3ccc(C#N)cn3)no2)ccn1 +COCCCn1cnc2c(Cl)cc(Cl)cc2c1=O +COC(=O)c1cc(Br)cc(C)c1OC +N#CCOc1cccc(CC(=O)Nc2ccc(-n3cncn3)cc2)c1 +CCCc1cc(=O)[nH]c(SCC(=O)Nc2ccccc2C(N)=O)n1 +Cc1nc2cc(NC(=O)Cn3nnc4ccccc4c3=O)ccc2o1 +Cc1cc(CC(=O)NCC2(Cc3ccccc3)CCC2)n[nH]1 +CCCC1CN(C(=O)c2cccc(NC(=O)c3ccco3)c2)CCO1 +C=CCn1nc(C(=O)OCC)c2c1CCN(Cc1cnn(C)c1)C2 +Cc1ccc(-n2c(=O)c(N)c(C)n2C)c(Br)c1 +Cc1ccc2ccc3cc(C(=O)NCC4CCCO4)[nH]c3c2n1 +Cc1ccc(-n2nnc(CO)c2-c2ccccc2C)cc1 +CC(CO)C(C)NC(=O)NCc1ccnc(OC(C)(C)C)c1 +CCCNC(=O)c1ccccc1NC(=O)C(CC)OC +COc1cc(C(=O)Nc2cccc(C)c2C)cc2c1OCCO2 +Cc1nc(C)c(CNC(=O)Nc2cc(-c3nnco3)ccc2C)s1 +CN1CCC(Sc2nc3ccc(C(F)(F)F)cc3[nH]2)C1=O +N#Cc1cccc(NC(=O)CSc2ccc(O)cc2)c1 +Cc1oc2cc3oc(=O)c(CC(=O)NCCCO)c(C)c3cc2c1C +O=C(CCC(O)c1ccccc1)Nc1ccc2c(c1)OCO2 +Cc1cnc(NC(=O)c2cccc3c2OCO3)s1 +O=C(NC(CO)c1ccccc1)c1cc2c(OC(F)F)cccc2[nH]1 +Cc1ccc(CC(C)NC(=O)C(C(C)C)N2CCCC2=O)c(C)c1 +Cc1nc2cc3c(cc2n(CCCO)c1=O)CCCC3 +Cc1ccc(OCCC(=O)N2CCC3(CC2)CNC(=O)C3)cc1C +Cc1ccc(S(=O)(=O)NCC(C)NC(=O)c2ccccc2)cc1 +CCOC(=O)c1ccc(N2CCN(C(=O)CC(C)(C)C)CC2)nc1 +COC(=O)CN(Cc1cnc2ncccn12)C(C)C +O=C(c1ccc(F)cc1)N1CCCC(c2nnc3n2CCCCC3)C1 +COc1cccc(OCC(=O)Nc2c(F)cccc2F)c1 +CCc1onc(C)c1NC(=O)NCCCN1CC(C)OC(C)C1 +N#Cc1cccc(NCCC(=O)c2ccc3c(c2)OCCO3)c1 +CC(C)C(=O)N1CCCC(c2ccnc(-c3ccc(F)cc3)n2)C1 +COCCN1CCN(Cc2nnc(-c3ccccc3C)o2)CC1=O +Cc1ccc(Nc2cc(=O)[nH]c(=O)[nH]2)cc1Cl +CC(=O)Nc1ccc(C(=O)OCc2ccccc2C#N)s1 +CC(=O)c1cccc(OCC(=O)NC(C)c2ccc3c(c2)OCO3)c1 +O=C(NC1CCCC1)C1CCCN(C(=O)c2cc3cccnn3c2)C1 +CC(N)C(=O)OCc1ccc2c(c1)N(C)C(=O)CCO2 +Cc1cc(C)c(NC(=O)COC(=O)CC2CC3CCC2C3)c(C)c1 +CCC(C)NC(=O)C1(c2cc(-c3ccccc3F)on2)CC1 +COc1ccccc1-n1c(SCC(N)=O)nnc1N1CCCCC1 +Cc1cc(N)ccc1NC(=O)CCSc1ncn[nH]1 +C=CCN(CC=C)C(=O)CN1c2ccc(S(N)(=O)=O)cc2CC1C +CCN(CC(C)C#N)C(=O)c1ccn(-c2ccccc2Cl)n1 +CCCCOc1ncccc1CNC(=O)N1CCOCC1C +N#Cc1ccccc1CN1CCC(OC(=O)CCc2ccco2)CC1 +Cc1nc(CNC(=O)C(CC(C)C)NC(N)=O)c(C)s1 +Cc1c(C(=O)NCC2CCCO2)oc2ccccc12 +NC(=O)Nc1cccc(NC(=O)CCC(=O)c2ccc(F)cc2F)c1 +CCCn1cc(CNC(=O)c2ccc(Cl)cn2)cn1 +COCCN(Cc1cc2ccccc2s1)CC(F)F +CCOC(C)c1noc(CSc2nc3ccccc3nc2C)n1 +O=C(C1CCC1)N1CCOC(c2cccc(OC(F)F)c2)C1 +Cc1cc(C(=O)N(Cc2cnc3ccccn23)c2ccccc2)c(C)o1 +O=c1cnc2ccccc2n1Cc1nc2ncccn2n1 +Cc1c(C(=O)N(C)C(C)CC#N)cnn1-c1ccncc1 +CC(C)Cn1ccc2cc(NC(=O)N3CCC(O)C3)ccc21 +CC(O)CCc1nc2cc(NC(=O)C(C)C)ccc2[nH]1 +CC(C)C(NC(=O)c1cccs1)C(=O)NCCO +CC(=O)N1C=Cc2ccccc2C1CC(=O)Nc1c(C)cc(C)nc1C +COc1ccc(F)cc1NC(=O)c1cn(C)nc1-c1cccs1 +CCCCC(=O)Nc1nc(C(F)(F)F)cs1 +COC(=O)c1noc(C(=O)Nc2ccc(C(C)C)cc2)c1N +O=c1onc(-c2ncccn2)n1Cc1cccc(Br)c1 +COc1ccccc1OC(C)CNC(=O)N(C)C(C)C +CC1CN(C(=O)c2sccc2-n2cnnn2)CC(C)O1 +CNC(=O)c1ccc(=O)n(CC(=O)N(C)CC2CC2)c1 +O=C(Nc1ccccn1)N1CCCC(c2nncn2C2CC2)C1 +Cc1cc(-n2cnnn2)cc(NC(=O)NCCN2CCOCC2)c1C +COc1c(Cl)cccc1NC(=O)c1ccc2c(c1)CCC(=O)N2 +C1=CC2CC1CC2CNc1ccccc1-n1cnnn1 +CCN(CC1CC1)C(=O)c1ccc(S(N)(=O)=O)c(C)c1 +C#CCN1CCN(C(=O)NCCCCN(C)c2ccccc2)CC1 +CCCCNc1ncnc2c1[nH]c1ccc(OC)cc12 +CCOC(=O)c1c(NC(=O)N2CCOCC2)sc2c1CCCC2 +Nc1cc2c(cc1NC(=O)Nc1ccccc1)OCO2 +CNC(=O)Nc1ccc(NC(=O)c2ccc(F)cc2)cc1 +CCn1cc(C(=O)c2ccccc2)c(=O)c2ccccc21 +O=S(=O)(NC(c1ccccc1)c1ccco1)c1ccccc1 +COc1ccc(CC(C)CNC(=O)CN2CCCS2(=O)=O)cc1 +Cc1cc(C)cc(CNc2ccccc2N2CCCC2=O)c1 +CCC(=O)Nc1ccc(CCC(=O)N2CCCC2)cc1 +COc1cccc(C(=O)COc2ncnc3sccc23)c1 +Nc1cccc(OCCC(=O)N2CCc3ccccc3C2)c1 +O=C(CSc1nnc(-c2ccc(F)cc2)o1)N1CCCC1 +CCCn1c(SCC(=O)NC)nc2sc3c(c2c1=O)CCC3 +O=C(OCc1ncc(-c2ccc(F)cc2)o1)c1c[nH]c(=O)c(Cl)c1 +COc1ccc(-c2nnc(SCC(=O)NC(C)C(C)C)n2N)cc1 +O=C(Cc1ccc[nH]1)NC1CC1c1c(F)cccc1Cl +O=C(NCC1COc2ccccc2C1)c1ccno1 +CN(C)C(=O)C1CCC2(CCN(C(=O)c3cnccn3)CC2)O1 +Cc1ccc(C(=O)NC2CCCCNC2=O)c(=O)[nH]1 +CCC1C(=O)NCCN1Cc1cccc(F)c1F +Nc1cccc(Cn2ccnc2-c2ccc(F)cc2)c1 +O=C(CNC(=O)c1ccc(=O)[nH]c1)NCCc1cccs1 +Cn1cnc(-c2nc(-c3ccc(N)cc3)cs2)c1 +COCC1CCC2C(CCN2S(=O)(=O)c2cccc(C)c2)O1 +CCC(C)(C)NC(=O)NCc1ccc(OC)c(OC)c1 +COc1ccc(-c2nc(C(=O)OC(C)C(N)=O)cs2)cc1 +Cc1nsc(NC(=O)c2ccc(N3CCC(O)CC3)cc2)n1 +COC(=O)c1cc(Cn2c3c(sc2=O)CCCC3)c(C)s1 +NC(=O)c1ccccc1NCC(=O)N1CCCc2ccccc21 +O=C(NCc1ccccc1OC1CCC1)N1CCC2(CCOC2)C1 +Cc1cnccc1C1NCCc2cc(F)c(F)c(F)c21 +Cc1ccccc1C(C)NC(=O)C(C)NC(=O)Nc1ccccc1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccccc2Cl)cc1 +CC(NC(=O)NCc1cccs1)c1ccc2c(c1)CCC(=O)N2 +O=C(COc1ccc(NC(=O)C2CC2)cn1)NCC1CCCO1 +COC(=O)c1ccc2c(c1)nc1n2C(CNC(=O)C2CC2)COC1 +COCC12CCCOC1CCN(C(=O)c1cccn1C)C2 +COc1ccnc(NC(=O)CCCn2nnc(-c3ccccc3)n2)c1 +CNC(=O)C1CCCN1C(=O)c1cc(N)ccc1Cl +Cc1c(NC(=O)N2CCC(CC(=O)N(C)C)CC2)cccc1N(C)C +Cn1cnc(CNC(=O)C(NC(=O)OC(C)(C)C)C(C)(C)C)n1 +CCNC(=O)c1ccc(NC(=O)NC2CCOc3ccccc32)cc1 +CC(=O)Nc1ccc(CC(=O)Oc2cccc(C(F)(F)F)c2)cc1 +CCNC(=O)c1ccc(Cl)cc1NCC(=O)Nc1cc(C)nn1C +Cc1ccc(C#N)c(=O)n1CCOc1cccc2ccccc12 +COc1ccc(C)cc1C(=O)CN1CCc2ccccc2C1 +Cn1ccc2c(OCC(=O)Nc3cccc(F)c3)cccc2c1=O +COC(=O)Cn1cc(NC(=O)c2ccc(Cl)cc2F)cn1 +Cc1nn(CC(=O)N2CCC(C)CC2)c(C)c1Br +CC(C)Oc1cncc(C(=O)NCc2ccccc2)c1 +Cc1cccnc1NC(=O)c1sc(-n2cccc2)nc1C +CCn1c(SCC(=O)NC)nnc1-c1ccc(OC)c(OC)c1 +N#CC(Cc1ccc(O)cc1)C(=O)N1CCCCC1 +O=C(C1Cc2cc(Cl)ccc2O1)N1CCc2ccccc2C1 +Cc1noc(C2CCCN(Cc3ccc(F)c(Cl)c3)C2)n1 +FC(F)(F)c1nc2ccc(Br)cn2n1 +Cc1nonc1NC(=O)Cn1nnc(-c2ccccc2)n1 +O=C(COc1ccc2c(c1)CCC2)NCC(=O)Nc1ccc(F)cc1 +Cn1nc(CNC(=O)Nc2ccccc2)c2ccccc2c1=O +CCc1c(C)nc2n(c1=O)C(CC(=O)Nc1nccs1)CS2 +CC1(NC(=O)CNC(=O)c2ccc(F)c(F)c2)CCOCC1 +Cc1ccccc1C(=O)N1CCC(C(=O)Oc2ccc(C#N)cc2)CC1 +CC1CN(S(=O)(=O)NCCOCCO)CC(C)O1 +CC(C)Cc1nnc(NC(=O)CSc2ccc(F)c(F)c2)s1 +CC(C)(C)Nc1ncc(Br)c2cc(N)ccc12 +O=C(C1CC1)N1CCC2(CC1)CC(OCc1ccccn1)CO2 +CC(CNC(=O)c1cccn1-c1cccnc1)c1ccccc1 +CCc1noc(CC)c1CNC(=O)CCc1ccncc1 +O=C1CC(c2nc(-c3cccc(Cl)c3)c[nH]2)CN1C1CC1 +CC1(C)CC2(CCO1)OC(=O)CC2C(=O)NCCc1ccccc1 +Cc1cc(C(=O)NCCN2CCc3ccccc32)on1 +CCCc1ccc(S(=O)(=O)NCCCO)cc1 +COCCOc1ccc(NC(=O)N(C)Cc2ccc(C)s2)cn1 +CCNC(=O)CNC(=O)NC1CC1c1ccccc1C(F)(F)F +O=C(Nc1c(Cl)cccc1Cl)c1cc[nH]n1 +CC(NC(=O)C1CCN(C(=O)C(C)(C)C)CC1)c1ccccn1 +Cc1cc(=O)n2nc(CC(=O)NCCc3ccccc3)nc2[nH]1 +CCOC(=O)C1CCC(=O)N1c1ccc(C)c(C)c1 +C#CCCNC(=O)c1ccc(Oc2ccccc2)cc1 +CC(O)(CNC(=O)Nc1ccc2oc(=O)ccc2c1)c1ccccc1 +Cc1ccc(C)c(SCC(=O)Nc2cccc(N)c2)c1 +COC(=O)c1ccc(C(=O)NC2CCSc3ccc(F)cc32)cc1 +Cc1ccc(Cl)cc1NC(=O)C(C)Sc1nnc(C)n1N +COC(=O)C(CO)NCc1ccc(C#N)cc1F +c1cncc(CN2CCOC3(CCN(Cc4nccs4)CC3)C2)c1 +CCOc1ccc(C(=O)NC2CCCc3c2cnn3C)cc1 +O=C(NCCCn1ccnc1)c1sc2cc(F)ccc2c1Cl +Cc1cc(C)n(CC(C)CNC(=O)c2ccccc2F)n1 +COCCC1CCN(C(=O)CN(C)C(=O)c2cccc(C)c2)CC1 +O=C(Nc1nncs1)c1nn(-c2ccc(F)c(F)c2)c2c1CCC2 +N#Cc1nc(-c2ccccc2)oc1S(=O)(=O)N1CCCCC1 +N#Cc1cccnc1Nc1nc2c(s1)CCCC2 +COc1nc(Nc2ccccc2OC)nc(OC)n1 +Clc1ccc(NC2=Nn3cnnc3SC2)cc1Cl +O=C(NCc1cccc(Cl)c1)Nc1nnc(C2CC2)s1 +CCCC(C)N1CC2(CCN(C(=O)c3cccnn3)CC2)OC1=O +Fc1cccc(-c2nc3c4c(ncn3n2)CCC4)c1F +CC(C)c1nc(CN(C)C(=O)c2ccccc2-n2cncn2)cs1 +Cc1c(Cl)cnn1CCC(=O)Nc1ccccc1 +Cc1ccc(NC(=O)CN(C)Cc2cnc3ccsc3c2)nc1 +Cc1ccc(CN(C)C(=O)CCc2nc3ccccc3c(=O)[nH]2)c(C)c1 +CC(OC(=O)c1cc(-c2ccco2)[nH]n1)c1ccc(F)c(F)c1 +CCN(C)C(=O)c1cccc(C(=O)Nc2ccc(OC(F)F)cc2)c1 +CCCNC(=O)c1ccc2c(c1)N(CCC)C(=O)C1CCC(=O)N21 +COc1ccccc1Nc1ncccc1C(=O)N1CCCC(O)C1 +COc1ccc(OCC(=O)Nc2cc(C)nc3ccc(F)cc23)cc1 +Cc1noc(C)c1C(=O)NCC#CCOc1cccnc1 +O=C1COc2ccc(Cl)cc2CN1C1CCc2ccccc21 +Cn1cnc(-c2ccc(F)cc2)c1NC(=O)c1cccc(F)c1 +Cc1cc(C)c(NC(=O)c2cc3cnn(C)c3nc2N)c(C)c1 +CC(=O)Nc1cc(C(=O)NC2CCc3ccc(F)cc32)ccc1F +CCCC1(CC(=O)Nc2nccs2)CCOC(C)(C)C1 +COCC(=O)N1CCCC(c2ccnc(Nc3ncccn3)n2)C1 +O=C(NCCc1ccc(F)cc1)c1cc(=O)nc2cccnn12 +Cc1ccc(C(=O)NCC(O)c2ccc3ccccc3c2)c(C)n1 +CCC(CC)NC(=O)NCc1cccc(NC(=O)C2CCCO2)c1 +O=C(NCCN1CCOC(c2ccccc2)C1)c1ccco1 +Cc1ccc(CN(C(=O)Cc2c(F)cccc2F)C(C)C)o1 +COC(=O)NCC(=O)N1CCN(c2ccc3[nH]ncc3c2)C(=O)C1 +Fc1ccc(NCc2n[nH]c(-c3cnccn3)n2)cc1 +Cc1nnc2ccc(-c3cccc(NC(=O)C4CCCC4)c3)nn12 +COCc1csc(NC(=O)Cc2cccc(F)c2F)n1 +CC(C)OC(=O)C1=C(C(C)C)N(C)C(=O)NC1c1ccccn1 +COC(=O)COc1cccc(C(=O)Nc2cc[nH]n2)c1 +O=C(NCC#CCN1CCc2ccccc2C1)C1CC1 +CN(C(=O)c1cnn(C)c1)C1CCN(c2ccc(Cl)cc2)CC1 +COc1ccc2c(C)c(CC(=O)NCc3cccnc3)c(=O)oc2c1 +Cc1ccc(F)c(C(O)Cc2csc(C)n2)c1 +COc1ccc(OC)c(NCc2ccc3c(c2)OCCO3)c1 +Nc1ccccc1N1CCN(C(=O)c2ccc(F)cc2)CC1 +Cc1nc(Nc2nc3ccccc3o2)ncc1C(=O)N1CCOCC1 +O=C1CC(C(=O)NCCc2cc3ccccc3[nH]2)c2ccccc2N1 +COCCCCNc1cc(C(=O)N(C)C)ccc1Cl +COc1ccccc1OCCC(=O)N1CCCC1Cn1cccn1 +COC(=O)CC1CCCCN1S(=O)(=O)c1ccn(C)c1 +CC(C)OCc1cccc(NC(=O)C(NC(N)=O)C(C)C)c1 +O=C1NCCCn2cc(S(=O)(=O)NCc3ccc(F)cc3)cc21 +Cc1ccccc1CNC(=O)CCNS(C)(=O)=O +CN(C)C(=O)c1ccc(COc2ccc(Br)cc2)cc1 +O=C(CCNS(=O)(=O)c1cccnc1)NCc1ccccc1 +CC(=O)N1CCN(C(=O)C2CN(c3nc4ccccc4s3)C2)CC1 +CCOc1ccc(OCc2ccc(C(=O)OC)o2)cc1 +CC(C)Cc1nc(NC(=O)c2ccc3c(ccn3C)c2)n[nH]1 +COc1cc(N)ccc1NC(=O)c1ccc(O)c(Cl)c1 +CC1CN(C(=O)CCOc2ccc(F)cc2)CCO1 +O=C(Nc1ccc2c(c1)OCO2)c1cn2cccnc2n1 +CCN(Cc1ccccc1)C(=O)CNC(=O)Nc1ccccc1F +COc1ccc(C)cc1NC(=O)c1ccc(N2CCOC2=O)cc1 +O=S(=O)(Nc1ncccn1)c1ccc(F)c(F)c1 +COc1ccc(CNC(=O)N2CCOCC2CC(C)C)c(OC)c1 +Nc1c(Cl)ccc2c(C(=O)NCc3ccccn3)nccc12 +N#Cc1ccccc1OCCN1CCN(C(=O)CO)CC1 +O=C(Nc1cccc2c1CCCC2)c1ccncc1 +COc1ccc(OCCNC(=O)c2cccc(-n3cnnn3)c2)cc1 +COc1ccc(N2CC(C(=O)NCc3cccnc3)CC2=O)cc1 +CCC(=O)NCc1cc(=O)oc2cc(C)c(Cl)cc12 +Cc1c(C(=O)NCCS(N)(=O)=O)cnn1-c1ccc(F)cc1 +O=C(CSc1nncs1)NCc1ccccc1F +OCc1nnn(Cc2ccc(Cl)cc2)c1-c1ccncc1 +CCOC(=O)c1[nH]c(C)c(C(=O)NCCc2nccs2)c1C +COCc1nn(C)c2c1CN(S(=O)(=O)c1c(C)n[nH]c1C)CC2 +C=CCn1c(=O)oc2ccc(C(=O)NCc3ccccc3Cl)cc21 +CCC(C)NC(=O)c1ccc2c(c1)nc1n2CCCCC1 +CCOc1ccc(C(=O)NCc2ccnc(OC(C)(C)C)c2)cn1 +CCOC(=O)N1CCC(NC(=O)C(N)c2ccccc2)CC1 +COc1ccc(CNc2c(C#N)nnc3ccc(C)cc23)cc1OC +CCOC(=O)C1CCN(c2cn[nH]c(=O)c2)CC1 +CC1CCCN(C(=O)C2CCN(C(=O)c3cccc(F)c3)CC2)C1 +COc1ccc(C(=O)COc2cccc(N)c2)cc1 +Cc1ccccc1NC(=O)C1CCCN(c2cnn(C)c(=O)c2)C1 +CCC1CCCCC1OC(=O)Cn1ncc(=O)c2ccccc21 +Cc1c(NC(=O)c2ccc(N)cc2)c(=O)n(-c2ccccc2)n1C +Cc1nc(OCC(=O)Nc2ccc(Cl)cc2)c2ccccc2n1 +CCC(COC)NC(=O)NC1(C)Cc2ccccc2C1 +CCN(CC(C)C#N)C(=O)CSc1nc(C)cs1 +CCN(C(=O)Nc1cnn(C)c1)C(C)c1ccc(F)cc1 +O=C(NCc1nnc2n1CCCC2)c1ccc2c(c1)OCO2 +c1ccc(CCc2nc(-c3cnccn3)no2)nc1 +CC(=O)Nc1ccc(O)c(C(=O)NC(C)c2ccc(Cl)cc2)c1 +CC(C(=O)NCCNS(C)(=O)=O)c1cc2ccccc2o1 +N#Cc1ccc(CN2C=NS(=O)(=O)c3ccccc32)cc1 +CC(C)c1ccc(OC(=O)CCn2ccccc2=O)cc1 +CCc1nc(CN2CCN(C(=O)NCc3ccncc3)CC2)cs1 +Cc1cc(C)c2sc(NCc3ccccn3)nc2c1 +Nc1nc(-c2cccnc2)ncc1C(=O)NCc1ccncc1 +COC(=O)C(NC(=O)c1cnc(C)cn1)c1ccc(Cl)c(F)c1 +O=C(Cc1nc(-c2ccccn2)n[nH]1)Nc1ccccc1 +N#Cc1cccc(CNc2ccc(C(=O)NC3CCOCC3)cc2)c1 +COC(=O)c1ccc(NC(=O)C(C)Oc2ccc(C)cc2)s1 +Cc1nnc(CN(C)c2ccc(F)c(F)c2)n1C +CCc1nsc(N2CCN(C(=O)Cc3ccc[nH]3)CC2)n1 +Cc1nn2ccccc2c1C(=O)NCCNC(=O)C(C)C +CN1CC(C(=O)N(C)Cc2nc3ccccc3s2)CC1=O +CCCCNS(=O)(=O)c1cccc(C(=O)NC)c1 +Cn1c(=O)c2c(ncn2Cc2nnc(-c3ccccc3)o2)n(C)c1=O +CNc1ncc(CN(C)C(=O)c2ccc(-c3ccccc3)[nH]c2=O)cn1 +COc1cccc(CNCC(O)c2ccccc2F)c1 +CCCCC(NC1=NS(=O)(=O)c2ccccc21)C(N)=O +Oc1cc(O)cc(C2NCCc3ccc4[nH]ccc4c32)c1 +CS(=O)(=O)c1ccc(C(=O)NCCCNc2ccccc2)cc1 +Cc1ccc(CN2Cc3ncccc3C2=O)c(F)c1F +CC(C)CC(C(=O)NCCC(=O)N1CCCC1)N1CCCCC1=O +CCC(NCC(=O)NC(C)C)c1ccc(O)cc1 +CC(CNC(=O)Cc1cccc(F)c1F)Cn1cccn1 +CCN(CCc1nccs1)C(=O)c1ccc2c(c1)CCO2 +CCOc1cnc(C(=O)Nc2ccc(Cl)c(Cl)c2)cc1O +CC(=O)N1CCC(C(=O)Oc2cc(C)cc(C)c2C)CC1 +CCc1n[nH]c(=O)c(CNC(=O)NCCn2cccc2)c1CC +CC(C)c1nnc(CNc2ccccc2C(=O)C2CCCC2)o1 +CCc1onc(C)c1NC(=O)Cc1csc(-c2cccnc2)n1 +CC(C)OC(=O)CCNC(=O)C1CC(=O)N(C)C1 +CCCC1CN(C(=O)COCc2ccccc2Cl)CCO1 +Cc1nc(NCC2(Cn3cccn3)CC2)c2cnn(C)c2n1 +COC(=O)C(C)NS(=O)(=O)c1ccc(C(C)=O)cc1 +O=C(Cc1ccc[nH]1)N1CCC(c2c[nH]c3ccccc23)CC1 +COc1ccc(CNC(=O)NCC2(c3ccc(F)cc3F)CC2)cc1 +CC(=O)N1CCN(C(=O)COc2ccccc2C#N)CC1 +CCc1[nH]c(C(=O)NCC2CN(C3CC3)CCO2)c(C)c1C(=O)OC +CCc1ccc(CCNC(=O)Nc2cccnc2-n2cncn2)cc1 +Cc1cc(C(O)CNc2ccc(C#N)cc2)ccc1F +CC(=O)Oc1ccccc1OC(C)c1nn(C(C)=O)c2ccccc12 +COc1ccnc(NC(=O)c2ccc(OC(F)(F)F)cc2)c1 +CC(=O)NCc1ccc(-c2csc(N3CCCC3)n2)cc1 +CC(=O)Nc1ccccc1OCC(=O)NCC(C)C +Cc1ccc(S(=O)CC(=O)NCCC2CCCCC2)nc1 +Cn1c(CO)cnc1SCc1csc(CCc2ccccc2)n1 +CCN1C(=O)CC(C)(C)c2cc(S(=O)(=O)NCC(C)C)ccc21 +COc1cc(CN2CCOC(C#N)C2)cc(Cl)c1OC +Cc1cc(C(=O)N2CCN(C(=O)NC3CCC(O)CC3)CC2)c(C)o1 +O=C(NCCc1cc2ccccc2[nH]1)c1ccc2snnc2c1 +Cc1nn(C)c2ncc(NC(=O)CCC(=O)c3ccccc3)cc12 +COc1ccc(C(O)CNC(=O)c2cccs2)cc1 +O=C(c1ccoc1)N1CCCC(C(=O)N2CCOCC2)C1 +Cc1noc2ncnc(N3CCN(Cc4ccc(Cl)cc4)CC3)c12 +N#Cc1ccccc1-c1ccccc1C(=O)NC1CCC(O)CC1 +Nc1cccnc1NCCNC(=O)NC1CCCCC1 +Cc1nnc(CNC(=O)c2cccc(Oc3ccccn3)c2)o1 +O=S(=O)(NCCOc1ccc2c(c1)OCO2)c1ccc(F)cc1 +CC(C)C(Sc1nc(N)c(C#N)cc1C#N)C(=O)NC(C)(C)C +Cc1ccc(NC(=O)Nc2ccc3c(c2)CCC(=O)N3C)cc1C +COc1ccc(CO)cc1OCCc1ccc(Cl)cc1 +Cc1cccc(-n2ncc(C(=O)NCc3ccccc3)c2C)c1 +CCOc1cccc(N2CCN(Cc3c[nH]nc3C(C)(C)C)CC2)n1 +CC(C)(C)OC(=O)N1CCCOC(C(=O)CN)C1 +COC1CCCC(OC(=O)CC(c2ccccc2)C(F)(F)F)C1 +COc1ccc2oc(C(=O)OCC(=O)N3CCCC(C)C3)c(C)c2c1 +O=c1c2ccccc2nc(SCCCO)n1-c1ccc(F)cc1F +Cc1nn(C)cc1-c1nnc(C(C)n2ncc(Cl)c2C)o1 +CC(C)C(C)NC(=O)C1CCN(Cc2cnc(C3CCC3)s2)CC1 +CC(=O)NCCNC(=O)c1cc(C2CC2)nc2c1cnn2C(C)C +CCC1C(=O)NCCN1Cc1cc(F)c(F)cc1F +CC(C)(C)OC(=O)N1CCC(NC(=O)c2ccncc2)CC1 +COc1cccc(CN(C)C(=O)COc2cc(C)ccc2C(N)=O)c1 +CCc1nc(-c2ccccc2OCC(=O)NC(C)C)no1 +CC1COCCN1C(=O)c1ccccc1OCC(N)=O +CCCC(=O)Nc1ccc(S(=O)(=O)Nc2cccc(C)n2)cc1 +COC(=O)CN(Cc1ncccc1C(F)(F)F)C1CCCC1 +CC1CC1CNC(=O)c1cc(Cl)c2c(c1)OCO2 +COCCNC(=O)Nc1cc(Cl)ccc1N1CCCC1 +Cn1nccc1C(=O)N1CC2(CCN(S(C)(=O)=O)C2)C1 +N#Cc1ccc(S(=O)(=O)NCc2ccn(-c3ccccc3)n2)cc1 +Cc1cccc(C(C)C)c1NC(=O)NCC(=O)NC1CC1 +O=C(COc1ccc2c(c1)CCC(=O)N2)NCc1cccnc1 +O=C(NCCc1ccc(F)cc1)c1cccc2[nH]ccc12 +CCCC(=O)Nc1ccc(CC(=O)N2CCCC2C(N)=O)cc1 +CCCN(CCO)C(=O)Nc1cc(-n2cnnn2)ccc1F +CCn1nc(C(=O)NC)c2c1CCC(NCc1ccc(C)cc1)C2 +COc1ccc(-c2ccc(CNc3nc(C)n[nH]3)o2)cc1Cl +COc1ccc(-c2nc3cc(OC)c(OC)cc3n2CCO)cc1 +COc1ccc(O)c(C(=O)NCC2CC=CCC2)c1 +COCCCNC(=O)c1ccc(-c2cccc(C)c2)[nH]c1=O +CC(=O)N(CCc1ccccc1)CC(=O)N(C)c1nccs1 +O=C(CCCc1ccccc1)N1CCCC(O)(CO)CC1 +Cc1nnc(-c2cc(C)n(CC(=O)Nc3ccc(C)c(C)c3)c2C)o1 +Cc1ccc(N)c2ccnc(Nc3cccc(O)c3)c12 +CCNC(=O)CN(C)C(=O)C1(c2cccc(C)c2)CC1 +Cc1cc(CN(C)C(=O)Nc2cccc(C(F)(F)F)c2)no1 +CC(C)c1cc(NC(=O)c2ccc3c(c2)CCN3S(C)(=O)=O)[nH]n1 +CC(=O)Nc1ccccc1Oc1nnnn1-c1ccccc1 +CCOC(=O)c1[nH]cc(-c2ccc(CC)cc2)c1N +Cc1ccccc1NC(=O)c1cccc(S(C)(=O)=O)c1 +COc1ccccc1CN(C(=O)c1ccc(CO)cc1)C1CC1 +CC(=O)Nc1ccc(F)c(C(=O)Nc2nc(C(C)=O)cs2)c1 +CCCCC(=O)Nc1ccc(NC(=O)c2ccco2)nc1 +Cc1ccc(OCC(C)NC(=O)NC2CCOC2C)cc1 +Cc1ccc(C#N)c(N2CC3CC(O)C(O)CC3C2)n1 +O=C(COn1nnc2ccccc21)NCc1ccccc1F +COc1ccc(OC(C)C(=O)Nc2cccc(O)c2)cc1 +O=C(CSc1ncc2ccccn12)N1CCCC1 +COc1cc(CNC(=O)c2cc(C)oc2C)cc(OC)c1OC +CCN(CCOc1ccc(OC)cc1)C(=O)c1cn2ccsc2n1 +CCN(CC)S(=O)(=O)N(C)Cc1cc(Cl)ccc1OC +Cc1nc2ccc(NC(=O)Cc3ccc4c(c3)CCC4)cc2s1 +O=C(c1ccno1)N1CCOCC(Oc2cnccn2)C1 +Cc1cc(CN2CCN(C(=O)Nc3ccc4c(c3)CCC4)CC2)on1 +Cc1nccc(NC(=O)c2cncc(F)c2)c1Cl +CN(C)S(=O)(=O)Nc1cnn(C2CCOC2)c1 +CC(C(=O)NCCNC(=O)c1ccccc1O)c1ccsc1 +O=C(CC1CCCCC1)Nc1ccn(CCc2ccncc2)n1 +COCc1cc(C(=O)Nc2cc(C)ccc2OC)ccc1F +O=C(Cc1cccc(F)c1)Nc1ccc(NC(=O)NC2CC2)cc1 +CCN(CC(=O)N(C)C)C(=O)CNC(=O)c1ccsc1 +CS(=O)(=O)N(CC(=O)NC1CC1)c1cccc2ccccc12 +CCOc1cc(C#N)ccc1OC(=O)c1ccc(C(F)(F)F)nc1 +O=C(Nc1ccc2c(c1)OCCCO2)c1ccsc1 +CCNC(=O)C1CCC(C)(C(=O)NCc2cnc(C)cn2)C1(C)C +COC(=O)c1cccn2nc(-c3cccc(O)c3)nc12 +CCOCC1CCCN(S(=O)(=O)c2cccc(Cl)c2C#N)C1 +Cc1nn(C)c(C)c1C(C)NC(=O)NCC(=O)NC(C)(C)C +COCc1cc(CC2CC(NC(=O)C3CCC3)C2(C)C)no1 +Cc1nc2c(c(C)c1CC(=O)NCc1cccc(C#N)c1)c(=O)[nH]n2C +COc1ccc2cc(CNc3ccccc3)c(=O)[nH]c2c1 +O=C(C1CC1c1ccc(F)cc1)N1CCN(c2cnccn2)CC1 +CC1CCCCC1CNc1ccc(C(N)=O)cc1N +CCC(C)NC(=O)CNC(=O)COc1ccccc1 +CNC(=O)CCNC(=O)c1cc2c(s1)CCCCC2 +CCS(=O)(=O)c1ccc(-c2nnc(NC(=O)C3CCCC3)o2)cc1 +O=C(NCc1cnn(Cc2ccccc2)c1)c1ccco1 +Cc1nccn1CCN1CCN(CC(=O)NCC2CCCO2)CC1 +COc1ccc(Cl)cc1C(=O)NCc1ccsc1 +Cc1ccc(C(C)NC(=O)NCc2cccc(OC(F)F)c2)o1 +CCCn1nc(NC(=O)CC)c2cc3ccccc3nc21 +c1ccc2nc(-n3nc(-c4ccncc4)c4c3CCNC4)ccc2c1 +Cn1nccc1CCNC(=O)NCc1ccc(-n2cncn2)cc1 +CS(=O)(=O)N1CCCC(C(=O)Nc2cc(F)ccc2Cl)C1 +Cc1c(CCC(=O)N2c3ccccc3OCC2C)cnn1C +c1ccc(CCc2n[nH]c(-c3cccc(Oc4ncccn4)c3)n2)cc1 +COc1ccc(OCCC(=O)N(C)C)c(CO)c1 +COCCOC(=O)Nc1cccc(Cl)c1Cl +Cc1nc2sccc2c(=O)n1NC(=O)c1cccc2ccccc12 +Cc1cc(C(=O)N2CCN(Cc3cnnn3C)CC2)c(C)o1 +C=CCNC(=O)Nc1ccc2c(c1)CN(C(=O)c1cccs1)CC2 +CC(C)c1nc(C2CCCN(C(=O)c3cc(C4CC4)[nH]n3)C2)no1 +CC(C)C=c1[nH]c(=O)c(=Cc2ccccc2)[nH]c1=O +CC(=O)c1cc(C(=O)N(CC(O)c2ccc(F)cc2)C2CC2)n(C)c1 +CCc1nc2n(n1)CCCC2Nc1ncnc2c1oc1ccccc12 +CCc1noc(C)c1C(=O)OC(C)C(=O)c1ccc(OC)cc1 +CCOc1ccc(-c2cc(CO)c(C)o2)cc1OCC +O=C(Nc1nccs1)c1nc(-c2ccccc2)oc1C1CC1 +CC(=O)NCCNC(=O)C(C)OCC(F)(F)F +C=CCNc1ncnc2sc(C(=O)N3CCCC3)c(C)c12 +CC(C)c1nc(C(C)NC(=O)c2cc3ccccc3c(=O)[nH]2)cs1 +Cn1ncc2c(N3CCN(c4ncnc5[nH]cnc45)CC3)ncnc21 +CCn1cc(C(=O)C23CC4CC(CC(C4)C2)C3)cn1 +CC(=O)Nc1ccc(NC(=O)C2CCCN(C(=O)NC3CC3)C2)cc1 +CCCCSc1nnc(C)n1-c1cccc(OC)c1 +O=C(CCCNC(=O)c1cccnc1)NCc1csc(=O)[nH]1 +CCCc1nc(NC(=O)c2ccc(-n3ccnc3)nn2)sc1CC +Cc1ccc(C(C)NC(=O)C(C)OCC(F)(F)F)cc1F +Cc1ccc(CNC(=O)Cc2sc(C)nc2C)cc1 +COCCCNC(=O)C(O)c1ccc(OC)cc1 +CC(=O)N1CCC(c2ccnc(C(=O)NC3CCCC3)c2)CC1 +CNCC(=O)OCc1ccc(Br)cc1 +Cc1noc2ncn(CC(=O)Nc3ccc(C(C)C)cc3)c(=O)c12 +N#Cc1cnc(SCc2nn(-c3ccccc3)c3c2CCC3)nc1N +CN(C1CCCCC1)S(=O)(=O)NC(C1CC1)C1CC1 +CC(=O)Nc1sc2c(c1C(N)=O)CCN(Cc1ccccc1)C2 +Cc1c(CNC(=O)Nc2ccn(CCC(C)C)n2)cnn1C +CN(C)c1cccc(OCc2nc3c(s2)CCN3)c1 +Cn1ccnc1CCNS(=O)(=O)c1cnc(N)nc1 +O=C(Nc1ccc(F)cc1)c1nc2c(s1)COCC2 +Cc1nsc(N2CCN(Cc3cc(=O)c(O)co3)CC2)n1 +Cc1c(C(=O)NC(C)c2ccccc2)nnn1Cc1ccccc1 +COc1c[nH]c(CN2CCOC(C(F)(F)F)C2)cc1=O +O=C(NCc1ccccc1)c1cccc(OCc2nc(C3CC3)no2)c1 +O=C(Nc1cccc(N2CCCNC2=O)c1)NC1CCCC1 +Cc1cc(Br)ccc1C(=O)NCc1ccncc1 +COc1cccc(-n2ccc3c(nnc4ncnn43)c2=O)c1 +Cc1ccc(NC(=O)c2nc3ncc(Br)cn3n2)c(O)c1 +CC(=O)Oc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1 +CC(C)(C)OC(=O)n1ccc2cc(OCCN3CCOCC3)ccc21 +Cc1noc(C)c1CC(=O)OCc1cc(=O)n2ccsc2n1 +O=C(Cn1ccnc1)NCCCN1CCCCCC1=O +CC1(C)Cc2c(sc3[nH]c(=O)n(CCCO)c(=O)c23)CO1 +Cc1n[nH]cc1NC(=O)Cc1ccc(Br)cc1 +O=c1[nH]nc2c(S(=O)(=O)N3CCCC3)cccn12 +CCOc1ccc(NC(=O)C(C)NC(=O)c2cccc(C)c2)cc1 +Cc1nnnn1-c1cccc(NC(=O)NCc2ccco2)c1 +Cc1n[nH]c2ncc(NC(=O)C(C)(C)Oc3ccc(C#N)cc3)cc12 +CCC(C(=O)N1CCC(c2ccncc2)CC1)n1cccn1 +CC(CC(=O)Nc1ccccc1C(C)(C)C)C(N)=O +CC1(C)COCCN1C(=O)c1cc(F)cc(F)c1 +Cc1ccc(CNC(=O)c2ccccc2-n2cnnn2)cc1 +CCCS(=O)(=O)N1CCCC1c1ccccc1Cl +Cn1ccnc1SCc1cc2c(cc1Br)OCO2 +Cc1ccc2c(c1)C(Nc1cccc(Cl)c1)C(=O)N2 +CNC(=O)c1cccc(NCC(=O)Nc2cccc(C(C)=O)c2)c1C +O=C(NCCc1ccccc1)N1CCOC2(CCOCC2)C1 +CC1CCCN(C(=O)C2(C)CCCCN2C(=O)c2ccccc2)C1 +Cc1nc(CC(=O)NCc2oc3ccccc3c2C)cs1 +COc1ccc(C(=O)NC2CCCN(c3cc(C)ccc3F)C2)nn1 +CCc1cc(N)c2oc(C(=O)Nc3cccnc3)cc(=O)c2c1 +COc1cccc(NC(=O)N2CCOC(CN3CCOCC3)C2)c1 +CCC(CNC(=O)c1ccc(-c2nnc(C)o2)cc1)c1ccccc1 +CCOc1ccc2nc(N3CCN(C(=O)CC)CC3)sc2c1 +CC(=O)N1CC(C(=O)NCc2ccccc2Cl)C1 +CC(CC(=O)NCCCC(N)=O)c1ccc(F)cc1 +CCCC(=O)NCC(=O)OCc1cccc(F)c1 +COc1ccccc1C(=O)CCC(=O)NCc1ccc(C)cc1 +CN(C)C(=O)N1CCN(C(=O)Nc2ccc(Cl)c(F)c2)CC1 +COc1ccccc1Oc1cc(N2CCCC2)ncn1 +Cc1occc1CN(C)C(=O)C1CCCN1C(=O)c1cccs1 +Cc1noc(C)c1CSc1nc2sccc2c(=O)n1C +CCN(CC(=O)NC(C)C)C(=O)c1ncccc1O +CC1CC(Sc2nnc(-c3ccc(OC(F)F)cc3)o2)C(=O)O1 +Cc1cc(S(=O)(=O)N2CCCc3ccccc32)ccc1N +Cn1cc(CC2C(OCC3CC3)CCN2Cc2ccco2)cn1 +C=CCOC(=O)c1ccc(NC(=O)NC(C)C)cc1 +O=C(Cc1csc(NC(=O)c2ccco2)n1)Oc1cccc(F)c1 +CCc1nc2n(n1)CCCC2NC(=O)CC=Cc1ccc(F)cc1 +NS(=O)(=O)c1cccnc1Nc1cccc(Br)c1 +O=C(CC1CCCCC1)NC1CCC(C(=O)Nc2ccncc2)CC1 +Cc1nc(Nc2nc3ccccc3o2)nc(C)c1C +CCOc1ccnc(N2CCN(C(=O)COCC3CC3)CC2)n1 +CCOC(=O)CNC(=O)C(N)c1ccc(C)c(C)c1 +CCc1nnc(NC(=O)Cc2cc(-c3ccccc3)no2)s1 +CCC(C)C(C)NC(=O)CCS(=O)(=O)c1ccc(C)cc1 +COC(=O)CC1CN(Cc2ccc(-c3ccc(C)cc3)o2)CCO1 +Cc1cc(C)n(C(C)CC(=O)NCCN2CCc3ccccc3C2)n1 +CC(Sc1ccccc1)C(=O)Oc1cccc(C(=O)NC2CC2)c1 +c1cc2nc(N3CCCC3)sc2cc1Nc1ccc2nnnn2n1 +COc1ccc(OCC(=O)Nc2cccc(C)c2)cc1 +Cc1ccc(C(=O)Nc2ccc(NC(=O)C3CC3)cc2)cn1 +CCNC(=O)c1cccc(CNC(=O)C(C)CC)c1 +O=C(NCc1ccncc1)c1cnn(-c2ccccc2)n1 +CCOc1ccc(CNC(=O)c2ccnc(-c3ccsc3)c2)cc1 +CC(=O)C1(c2ccccc2)CCN(C(=O)C2CN(C)C(=O)N2)CC1 +CCOC(=O)c1cc(C)sc1NC(=O)c1ccccc1F +CCn1nccc1CN(C)S(=O)(=O)c1cnn(C)c1 +CC(c1ccc(-c2ccc3nc[nH]c3c2)cc1)N1CCOCC1 +CC(C)C1Oc2ccc(N)cc2N(Cc2ccccc2F)C1=O +CCC(Cn1c(=O)oc2ccccc21)NC(=O)c1cscn1 +CN(C)S(=O)(=O)c1cc(N)c2[nH]c(=O)oc2c1 +Cn1cc(N2CCC(NC(=O)NCc3cccs3)C2)cn1 +O=C(Oc1cccc(N2CCCC2=O)c1)c1cc(=O)[nH]c2ccccc12 +COC(=O)CN(C(=O)c1cccc(C#N)c1)c1cccc(F)c1 +CC1(O)CCC(Nc2cc(C(F)(F)F)ccn2)CC1 +CC1CN(CCCNC(=O)NCc2ccccc2Cl)CC(C)O1 +CC(C)c1cc(C2CCN(C(=O)Cc3ccncc3)CC2)[nH]n1 +Cc1ccc(-c2nnn(CC(=O)N3CC(C(N)=O)CCC3C)n2)cc1 +Cc1cccc(Nc2ccc(N3CCN(S(C)(=O)=O)CC3)nn2)n1 +CCOc1ccccc1CN(C)C(=O)Nc1nnc(C2CC2)s1 +O=C(c1n[nH]c(=O)c2ccccc12)N(Cc1ccco1)C1CCCC1 +COCCCNC(=O)Nc1cc(C)ccc1OC +CC(C)NC(=O)NC(c1nnc2n1CCC2)C(C)C +CCCc1ncncc1C(=O)N1CCC(O)(CC)C(O)C1 +CC(NC(=O)CN1CCCCCC1=O)c1ccccc1Cl +Cn1cc(-c2nc(COc3ccccc3C#N)cs2)cn1 +N#CCCCn1cnc2cc(Br)cnc21 +Cc1cccc(C(=O)NCc2nnnn2-c2ccc(C)c(C)c2)c1 +CCC(=O)N1CCc2ccc(NS(=O)(=O)c3ccccc3)cc2C1 +N#Cc1cccc(Cn2nc3ccccn3c2=O)c1 +O=C1CCCN1Cc1nnc2n1CCCN(C(=O)c1ccc[nH]1)C2 +CN(C)c1cccc(-c2nc3cc(N)ccc3n2C)c1F +CN1C(=O)COc2ccc(NC(=O)Cc3ccc(F)cc3F)cc21 +CCn1c(SCC(=O)Nc2cc(C)no2)nnc1-c1ccccc1 +CC(C)(C)CC(=O)NCc1nc(-c2ccco2)no1 +CCC(=O)N1CCCCC1C(=O)NCCn1cc(C)cn1 +CSc1ccc2c(c1)CCN(C(=O)Nc1c(C)cc(C)nc1C)C2 +CC(C)(C)CCNC(=O)NC1CCCCNC1=O +CC(C)n1cnnc1SCc1nnc(-c2ccccc2Cl)o1 +CC(=O)Nc1ccc(C(=O)NC2(C(=O)OC(C)(C)C)CCCC2)cc1 +Cc1csc(C(C#N)C(=O)CCc2cccc(F)c2F)n1 +Cc1cc(C(=O)NCCCN2CCCCCC2=O)c(C)o1 +CC1CCCCC1N(C)C(=O)CSc1nncn1C +Cn1nc2nc(NCc3ccccc3)nc(-c3cccc(F)c3)c2c1N +O=C(Nc1cc(F)cc(F)c1)c1cn(-c2ccccc2)nn1 +CN(C)S(=O)(=O)c1cccc(-c2nnc(-c3ccco3)o2)c1 +CCOc1ccccc1-c1nc2sc(CC)nn2c1CO +CCCCOc1ccc(C(=O)N2CCN(CC(C)O)CC2)cc1 +O=C(Nc1ccc(N2CCCC2=O)c(Cl)c1)c1cc[nH]n1 +COc1ccc(OCC(=O)Nc2nc(-c3ccc(C)o3)cs2)cc1 +CCc1ccc(CN(Cc2cccnc2)C(=O)C2CCCO2)cc1 +CNC(=O)c1ccc(CSc2nncn2C(C)C)cc1 +CC(NC(=O)Nc1ccc(CC#N)cc1)C(=O)NCc1ccccc1 +Cc1cc(C(=O)CN2CCOC(C)(C)C2)c(C)n1CC(F)(F)F +Cc1nn(C)c(C)c1CCNC(=O)CCc1ccc(C#N)cc1 +Cc1ccc(N2CC(C(=O)Nc3cccnc3)CC2=O)cc1Cl +COc1ccc(-c2nc(CN3CCOCC3C3CC3)co2)cc1 +NC(=O)c1cc(-c2csc(NC(=O)c3cccs3)n2)c[nH]1 +Cc1nc(C(=O)N(C)C)ccc1C(=O)NC(C(N)=O)C(C)(C)C +COc1cccc2c1OCC(CNC(=O)N1CCCC1)C2 +CC(NC(=O)c1cc(Cl)cc(Cl)c1)C(=O)NC(C)(C)C +C#CCN1CCN(C(=O)NC(C)c2ccc(OC)cc2OC)CC1 +CS(=O)c1cccc(NC(=O)c2ccc(F)cc2Cl)c1 +Cc1cc(NC(=O)CSc2nc(=O)[nH]c3c2CCC3)no1 +O=C(COc1ccccc1F)N(Cc1ccc(F)cc1)C1CC1 +CCc1cccc(C)c1NC(=O)NCCN(C)c1ccccc1 +Cc1nc(-c2cccc(CNC(=O)Nc3ccc(F)nc3)c2)n[nH]1 +O=C(Nc1nncs1)C1CCN(C(=O)c2cccc(F)c2)CC1 +CCN(Cc1cnc2ccccn12)C(=O)c1cccc(C#N)c1 +COc1cccc2c1OCC(C(=O)N1CCCC1Cn1cccn1)C2 +CNC(=O)c1ccc(CNc2ccccc2OCC2CC2)cc1 +Cc1ccc(C2=NC(=O)C(C#N)C(c3ccco3)=C2)cc1 +Cc1ccc(N2CC(NC(=O)Nc3cc(F)ccc3F)CC2=O)cc1 +O=C(NCCOc1cccc(F)c1)c1ccc2c(c1)CCO2 +COc1cccc(CNC(=O)C2COc3ccc(F)cc3C2)c1OC +CC(=O)N1CCN(C(=O)CN(C)c2nc3ccccc3s2)CC1 +CC(C)CCNC(=O)c1snc(-c2ccccc2)c1N +O=C(NCC1COCc2nc3cccnc3n21)c1ccncc1 +Cn1cccc1C(=O)N1CCN(c2ncnc3ccccc23)CC1 +Cc1ccc(NC(=O)c2nnc(-c3ccc(N)cc3)s2)cc1 +CN(Cc1ccc(OC(F)(F)F)cc1)C(=O)c1ccc(F)cc1 +CCc1c(C)sc(NC(=O)c2cccc(-n3cnnn3)c2)c1C#N +Nc1oc2ccc(F)cc2c1C(=O)c1ccccc1 +Cn1c(CCC(N)=O)nc2c1c(=O)[nH]c(=O)n2C +Cc1ccc(OC(=O)Cn2ncc3ccccc3c2=O)cc1C +CN(CC(=O)OCc1cccnc1)C(=O)c1cccs1 +Cc1n[nH]c(C)c1S(=O)(=O)NCC(=O)N(C)C +CC(=O)Nc1ccccc1OS(=O)(=O)c1cccnc1 +CCN(CC)C(=O)CNC(=O)NCCc1c[nH]c2cc(F)ccc12 +O=C(c1cnns1)N(Cc1ccccc1)CC1CCCO1 +Cc1ccc(OCC(O)CN2CCN(C(=O)C3CC3)CC2)c(C)c1 +CC1(CO)CCCC1NS(=O)(=O)c1cccc(F)c1C#N +CC1COCCN1C(=O)c1ccc(C(=O)N(C)C)cc1 +CC(=O)Nc1nc(C(=O)NCC(C)c2ccc(C)cc2)cs1 +O=c1c2cnc3nc(C4CCCCC4)nn3c2ccn1-c1nc[nH]n1 +Cc1cc(C(C)(C)C)ccc1OC(=O)Cn1ccc(=O)n(C)c1=O +O=C(Cc1cn2ccsc2n1)NCCCSc1ccc(F)cc1 +Cc1csc(SCC(=O)NC2CCCCC2C)n1 +NC(=O)c1c(NC(=O)c2ccc3ccccc3c2)sc2c1CCC2 +CC1CCN(C(=O)C(C)Sc2nnc(NC3CC3)s2)CC1 +CCOC(=O)Cc1nc(-c2ccccc2OC)n[nH]1 +COC(=O)N1CC(NC(=O)c2ccc(OC)c(-c3ccccc3)c2)C1 +O=C(COc1ccc2c(c1)OCO2)Nc1nc2c(s1)CCCC2 +COc1cc(-c2nnc(-c3cccc(N)c3)o2)cc(OC)c1OC +Cc1noc(C)c1C(C)NC(=O)CCc1nc(-c2cccnc2)no1 +O=C1OC(C(=O)NCCOc2ccccc2)Cc2ccccc21 +Cc1ccc(N2CC(C(=O)N3CCC4(CCC4)C3)CCC2=O)cc1C +C=CCNS(=O)(=O)c1cccc(C(=O)NCC(C)C)c1 +Cc1c(CC(=O)N(C)C)c2c(n1C1CCCCC1)CC(C)(C)CC2=O +CN(Cc1noc(C2CCC2)n1)C(=O)c1c[nH]nc1-c1ccccc1 +COC(=O)C(C)N1C(=O)C(C(C)C)Oc2ccc(N)nc21 +COc1cccc(CCC(=O)N2CCCCC2C(=O)N2CCCC2)c1 +Cc1nnc(SCC(=O)N2CCCC2)n(N)c1=O +CS(=O)(=O)NC1CCSc2ccc(Cl)cc21 +COCC(C)OC(=O)CCc1ccc2c(c1)OCCCO2 +CNC(=O)COC(=O)COc1ccccc1C(C)(C)C +CN(CC(=O)Nc1cccc(F)c1)c1nccc(C(F)(F)F)n1 +CCN(Cc1ccoc1)C(=O)Nc1cc(F)ccc1OC +CCc1cc(N)cc(C)c1NC(=O)COc1ccc(Cl)cc1C +CC1CCN(C(=O)CNc2ccc(F)c(C(N)=O)c2)CC1 +CNC(=O)c1cccc(CNC(=O)c2cn(C)nc2C(C)(C)C)c1 +CC(CC(=O)N1CCCC1c1noc(C2CC2)n1)n1cccc1 +COc1ccc(CC2Oc3cc(N)ccc3N(C(C)C)C2=O)cc1 +CSc1ccc(C(=O)NCc2nc(-c3ccncc3)cs2)cn1 +Cc1cc(C)nc(N2CCC(c3ncncc3S(C)(=O)=O)CC2)n1 +Cc1c(Cl)cccc1-n1nc(CC#N)c(=O)cc1C +COc1cc(-c2ncc(N)cn2)ccc1OCC(C)C +Cc1nc(C)c(CCC(=O)NC(C)CCC(C)C)c(=O)[nH]1 +COc1ccc(S(=O)(=O)NCc2ccc(Cl)cc2)cc1OC +CCNC(=O)C(C)Oc1c(CO)cccc1OCC +CC1CCN(C(=O)C(NC(=O)c2ccccc2F)C(C)C)C(C)C1 +C#CCNC(=O)c1cccc(COc2ccc(C)nc2)c1 +CC(C)CCC(C)NC(=O)c1cnc2c(cnn2C(C)C)c1 +CCOc1cc(NC(=O)CCc2ccsc2)ccc1OC +CCOC(=O)c1cc2sccc2n1CC(=O)OC(C)C +O=C(NCC(O)C1CCCC1)c1cccnc1N1CCOCC1 +COc1ccc(CCNC(=O)C2Cc3ccccc3C(=O)O2)cc1 +CCCCNC(=O)Nc1cccc(N2CCNC2=O)c1 +CC(CO)C(C)NC(=O)Nc1ccc(Oc2cccc(C#N)c2)cc1 +CC(C)C(=O)c1ccc(S(=O)(=O)NCc2ccccn2)cc1 +CCC(=O)c1cccc(S(=O)(=O)Nc2ccc(F)cc2OC)c1 +O=C(Oc1ccc(F)cc1Br)c1cnccn1 +O=C(Cc1cn2ccsc2n1)N1CCc2ccc(Cl)cc2C1 +CNS(=O)(=O)c1ccc(NC(=O)c2cccc(C)c2)cc1 +CCc1noc2nc(C)n(CC(=O)NCCc3cccs3)c(=O)c12 +Cc1cc(C(=O)N2CCN(Cc3cccnc3C)CC2)c(C)o1 +CCC(NC(=O)c1cccc(S(=O)(=O)NC)c1)C(C)C +Cc1cccc(-n2ccnc2S(=O)(=O)Cc2csc(C)n2)c1 +CCc1ccc(N(C)S(=O)(=O)c2ccc(C)s2)cc1N +COc1ccc(Br)cc1C1CC2(C)NC(=O)C1C(=O)N2 +N#Cc1csc(CN2CCCC2COc2ccccc2)c1 +CCN(Cc1nc(-c2ccccc2)no1)C(=O)c1ccccc1F +CN(C(=O)Cc1ccc(S(=O)(=O)C(F)F)cc1)c1nccs1 +CC1CN(CCCNC(=O)Nc2cccc(C#N)c2)CC(C)O1 +O=c1n(CCn2cccn2)nnn1-c1cccs1 +N#CCc1nc2ccc(F)cc2n1-c1ccc(C#N)cn1 +CS(=O)(=O)c1ccc(-c2ccc3c(c2)C(=O)C(=O)N3)cc1 +COc1ccc(-n2cnnc2CN(C)S(C)(=O)=O)cc1 +Cc1ccccc1N1CCN(C(=O)CN2CCOC2=O)C(C)C1 +O=C(CSc1nnc(-c2cccc(F)c2)o1)N1CCCC1 +Cc1ccccc1-n1nc(C(=O)Nc2nccn(C)c2=O)c2c1CCC2 +O=C(Cc1ccc(F)cc1Cl)N1CCn2c(nnc2C2CC2)C1 +CNC(=O)COC1COC2(CCCN(C(=O)c3cccnc3)C2)C1 +Cc1ncsc1COC(=O)c1cnn(C)c1-n1cccc1 +Cc1noc(C)c1C(C)NC(=O)CCNC(=O)c1ccco1 +CCC(CC)NC(=O)Nc1cccc(-n2nnnc2SC)c1 +CC(C)(C)NC(=O)N1CCC(CNS(=O)(=O)C2CC2)CC1 +CCOC(=O)CCC(C)NC(=O)Nc1ccc(C)c(F)c1 +COCc1ccccc1NC(=O)Cc1coc2cc(C)ccc12 +Cc1nnc(CNC(=O)Cc2cccc(Br)c2)n1C +Cc1nnsc1-c1nnc2sc(Cc3ccccc3)nn12 +O=C(c1cccc(Oc2cnccn2)c1)N1CCCC1 +O=C(CCCN1CCOC1=O)NCc1cccnc1 +CN(C(=O)CNc1ccc(C#N)cc1)c1ccccc1 +O=C(Nc1ccc(F)cc1)N1CCN(S(=O)(=O)C2CC2)CC1 +CC(C)(C)C(=O)NCCCC(=O)Oc1ccccc1 +Cc1cc(C)c(C(=O)NC2CCCc3ccccc32)c(=O)[nH]1 +CCOC(=O)C(C)(n1nnc2ccccc21)n1nnc2ccccc21 +CCCC(C)C(=O)N1CCN(Cc2cccs2)CC1 +Cc1ccc(CN(C(=O)Nc2nncs2)C(C)C)s1 +COc1ccc(F)c(NC(=O)c2ccc3c(c2)OCCO3)c1 +CCC1CCCN(C(=O)c2cc3ccccc3c(=O)[nH]2)C1 +COCC(=O)OCc1nc(-c2cccc(Cl)c2)no1 +CC1CN(C(=O)Nc2ccc(OC(F)F)c(F)c2)CCO1 +COC(=O)CCCn1c(CCO)nc2cc(F)ccc21 +C=CCCCN(C)C(=O)c1cccc(C)c1NC(=O)c1ccncc1 +CCOc1ccc(NC(=O)c2sc3ncn(C)c(=O)c3c2C)cc1 +CCN(CC)C(=O)C(C)N1CCN(C(=O)C(C)(C)C)CC1 +COCCN(Cc1cnn(C)c1)C(=O)CN1CCCC1=O +CC(=O)NCC(=O)NCCN1CCN(c2ccc(F)cc2)CC1 +CCOc1cccc(C(=O)C(C#N)c2nc3ccccc3[nH]2)c1 +N#CCc1ccc(-c2ccc(Cl)cc2)n(C2CC2)c1=O +Cc1nnc(NCc2nc(-c3cnccn3)n[nH]2)o1 +COc1ccc(NC(=O)COc2ccc(NC(C)=O)cc2)cc1Cl +Cc1cccc(-n2nc(C)cc2NC(=O)c2cnccn2)c1 +Cc1nnc(SCCNc2ncc(F)c(N(C)C)n2)s1 +COC(=O)c1cc(COc2ccc(C(=O)N(C)C)cc2)c(C)s1 +CSc1ccc(CN(C)C(=O)C2CCCO2)cc1 +Cc1nc(CNC(=O)c2cc3cc(C(F)(F)F)ccc3n2C)n[nH]1 +Nc1ccc(SCC(=O)NC2CCCCCC2)cc1 +CNC(=O)c1cccc(OCc2ccccc2F)c1 +CC(C(=O)N1Cc2cnc(C(C)(C)C)nc2C1)n1cncn1 +COC(=O)C(C)NC(=O)c1cc(Br)ccc1Cl +O=C(Nc1nc(-c2cccnc2)cs1)c1c(F)cccc1Cl +O=C(Cc1ccc(Cl)cc1)Oc1cccc(C(=O)NC2CC2)c1 +COC(=O)C1CCN(C(=O)c2ccn(C)c(=O)c2)c2ccccc21 +O=C(Nc1ccc(F)cc1)c1c[nH]c2ccccc2c1=O +COC1CCCC1OC(=O)Cn1cnc2c(oc3ccccc32)c1=O +COc1ccc(C(C)(C)CNC(=O)C(C)OC)cc1 +COC(=O)c1ccccc1NC(=O)COC(=O)c1ccc(O)cc1 +O=C(Nc1nc[nH]n1)c1ccc(CNC(=O)c2cccs2)cc1 +CS(=O)(=O)c1ccc(S(=O)(=O)N2CCOCC2)cc1 +O=C(CC(F)(F)F)NC1CC2C(=O)NCC(=O)N2C1 +Cn1cc(CN(c2nccs2)S(=O)(=O)c2ccccc2)cn1 +CCn1c(SCc2cccnc2)nnc1C1CC1 +CC(=O)Nc1ccccc1OCc1nc(-c2cccc(C)c2)no1 +CCn1nc(CC(N)=O)nc1COc1cccc(-n2cnnn2)c1 +Cc1cc(C)n2nc(SC(C)C(=O)NCC(F)(F)F)nc2n1 +O=C(COc1ccc2ccccc2c1)NCc1nncn1C1CC1 +CC(C)n1nc(O)c2c(-c3ccsc3)c3c(nc21)[nH]c(=O)n3C +CCOC(=O)N1CCN(C(=O)CCc2c[nH]c3ccccc23)CC1 +CCOC(=O)CN(C(=O)c1ccc(-c2ccccc2)cc1)C1CC1 +CNC(=O)c1ccc(NCC(=O)Nc2ccccc2OC)cc1 +CC1CCCC1NC(=O)c1ccc(C#CCO)cc1 +CC(=O)Oc1ccc(C(=O)c2ccc(F)cc2)cc1 +Cc1nc(-c2ccccn2)n(Cc2cc(=O)n3ccsc3n2)n1 +O=C(NCc1cn[nH]c1)c1n[nH]c(=O)c2ccccc12 +N#Cc1ccc(Cl)c(NCC(=O)NCc2cccs2)c1 +Cc1cnc(NC(=O)c2cc(-c3csc(C)n3)cn2C)s1 +CC(=O)Oc1ccc2c(=O)c(-c3nc4ccccc4n3C)c(C)oc2c1 +CC(Sc1ncc2ccccn12)C(=O)Nc1ccc2c(c1)OCO2 +CC(CNC(=O)NC1CCSc2ccccc21)N1CCOCC1 +Cc1ccccc1OCC(=O)N1CCC(Nc2cccnn2)CC1 +Cc1nc2c(c(C(F)(F)F)n1)CC(C(=O)NCC(C)(C)O)CC2 +CCc1nnc(SCc2nc3ccccc3c(=O)[nH]2)n1CC(C)C +Cc1cccc(C(C)C)c1NC(=O)CSc1nncn1C +CS(=O)(=O)c1ccc(CCCn2cc(N)cn2)cc1 +CCN(CC1CCOCC1)C(=O)C(c1cccc(C)c1)N(C)C +CC(C)(C)C(=O)Nc1cc(C2CC2)nn1-c1ccccc1 +COC(=O)Cc1cccc(-c2nn3c(CC(=O)OC)nnc3s2)c1 +Cc1nc(-c2cccs2)sc1C(=O)NC(C)C +COCc1cccc(C(=O)NCCc2nc3c(C)cccc3o2)c1 +O=C(NCCNC(=O)c1cccc(Cl)c1)c1ccccc1 +Cc1cc(C(=O)NCCCC(N)=O)nn1-c1ccccc1 +O=C(NCc1ccco1)c1ccc(NC(=O)N2CCOCC2)cc1 +CC(=O)c1cccc(OC(=O)C2Cc3ccccc3C(=O)O2)c1 +Nc1nonc1C(=O)OCc1ccccc1Cl +CC(=O)c1ccc(S(=O)(=O)NC2CCCCC2C)cc1 +CNC(=O)c1nsc(C(=O)NCc2cc(F)cc(F)c2)c1N +CN(Cc1ccncc1)C(=O)CNC(=O)OC(C)(C)C +Cc1ccc(-c2cc(C(=O)N3CCOCC3)ccn2)c(F)c1 +O=C(NCC(O)COc1ccc(C(F)(F)F)cc1)C1CCCC1 +CCCCNC(=O)NCc1ccc(OC(F)F)cc1 +CN(CC(=O)c1ccc[nH]1)C1CCN(C(=O)OC(C)(C)C)C1 +CC(C)c1nc(CC(=O)NCc2ccc(F)cc2)cs1 +O=C(NCc1ccc(F)cc1)C1CCC(=O)N1C1CCCC1 +Nc1cc(F)c(Oc2ccc3c(c2)OCO3)c(F)c1 +CCOc1c(Br)cc(Cl)cc1NCc1cncnc1 +Cc1cnc(C(=O)Nc2ccc(-n3ccnc3)nc2)cn1 +CNc1nnc(-c2cc3c([nH]c2=O)CCCC3)s1 +C#CCOc1ccc(CCNS(=O)(=O)c2ccc(C#N)cc2)cc1 +Cc1nc2ccccc2c2oc(C(=O)NCCCOC(C)C)cc12 +CC(C(=O)N1CCOCC1)S(=O)(=O)c1ccc(F)cc1F +CCCOc1nccnc1NC1CCN(C(=O)NCC)CC1 +N#Cc1c(CCCNc2ncc(C(F)(F)F)cc2Cl)n[nH]c1N +COC(=O)NCCCC(=O)Nc1cc(C)ccc1Br +CCN(CC)C(=O)COc1cccc(NC(=O)NC2CCCC2)c1 +CCOc1ccc(C#N)cc1NC(=O)NCCNc1ncccn1 +COC1CCN(C(=O)c2ccc3[nH]ccc3c2)C1Cc1cnn(C)c1 +COCCN(CC(C)C)C(=O)CN1C(=O)CSc2ccccc21 +NS(=O)(=O)CC1CCCN(C(=O)CCCC2CCCC2)C1 +O=C1CCCN1CCCNC(=O)C1(c2cccc(F)c2)CCCC1 +O=C(c1cccc(NCCCO)c1)N1CCc2ccccc21 +O=C(Nc1ccccc1)c1nnc(-c2ccccc2)s1 +Cc1cc(Br)ccc1C(=O)NCC1CCOC1 +COc1cc(C(=O)Nc2cccc(SC)c2)ccc1OC(F)F +O=C(COCC1CCCO1)Nc1ccc(Br)cc1 +O=S(=O)(c1ccccc1)N1CCOCC1C1CC1 +Cc1nc(C(C)C)sc1C(=O)NCc1ccc2c(c1)OCO2 +CC(C)CNC(=O)c1cnn(Cc2ccccc2)c1C(C)C +CCOc1cc(OCC)c(C(C)=O)cc1OCC +Cc1sc(-c2cccnc2)nc1OC(=O)C1CC1 +CC(CO)CNC(=O)NC(C)C(c1ccccc1)c1ccccc1 +COc1ccc(Cl)cc1NC(=O)CSc1nc(O)cc(O)n1 +CCc1cc(N2CCCC2c2noc(C(C)C)n2)ncn1 +O=C(CCNC(=O)NC1CCCCC1)NCC1(c2ccccc2)CC1 +CCn1cc(CN2CCN(C(=O)c3csc(C(C)C)c3)CC2)cn1 +Cc1nc(CN(C)Cc2nc(-c3cccnc3)no2)oc1C +COc1ccc(CC(=O)N(C)Cc2ccsc2)cc1 +CS(=O)(=O)NC(COc1ccccc1F)c1ccccc1 +CCCC1CN(C(=O)CCCc2ccc(C)s2)CCO1 +Cn1ccc(CN2CCN(C(=O)c3cc4ccccc4[nH]3)CC2)c1 +CN(C)S(=O)(=O)c1cccc(Cn2nccc2-c2ccncc2)c1 +Cc1cc(C)cc(C(C)NC(=O)CCC(=O)N2CCC(O)CC2)c1 +O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)NC1CCCCC1 +COc1ccc(-c2n[nH]cc2CN2CCCC(C#N)C2)cc1 +Cc1ccc(NC(=O)C(C)CC#N)cc1Br +O=C(CSc1ccc(Br)cc1)NCC1CCCO1 +CCCn1nccc1C(=O)NCC(=O)C(C)(C)C +CCCCC1C(=O)N(C)CCN1C(=O)CCOc1ccccc1 +CN(C)c1ccc(C(=O)Nc2cccc(CO)c2)cc1 +Cc1nc(CNC(=O)CSc2nccn2C)cs1 +O=C(COc1ccc2ccc(=O)oc2c1)NCCc1ccccc1F +CC(c1nc(C2CC2)no1)N1CCN(c2ccc(F)cc2)CC1 +CC1(CNC(=O)C2(c3ccc(F)cc3F)CCCC2)COC1 +CCNc1ncccc1COc1ccc(CO)cc1 +O=C(NCCO)c1ccc(F)c(S(=O)(=O)NC2CC2)c1 +COc1ccc(C2=CCN(S(=O)(=O)c3c(C)noc3C)CC2)cc1 +COC(=O)CN(C)c1ncc(Br)c2ccccc12 +CC(OCc1ccccc1)C(=O)OCC(=O)N1CCCC1 +Cc1cc(C(=O)N2CCC(NS(C)(=O)=O)CC2)c(C)o1 +O=c1[nH]nc(SCc2cc(-c3cccs3)on2)n1C1CC1 +C#CCOC(=O)c1cc(Cl)c2c(c1)OCCO2 +N#Cc1cccc(CN2CCC(c3nnc(-c4ccccc4)o3)C2)c1 +CCOc1ccc(OCC(=O)Nc2ccc(F)c(F)c2)cc1 +CCc1ccc(OCC(=O)NCc2nnc3ccccn23)cc1 +CC(=O)c1c(C)[nH]n(-c2nc3ccccc3s2)c1=O +Cc1ccc(C(C(=O)N2CCNCC2)N2CCOCC2)cc1 +N#CC1(NS(=O)(=O)CC2CCCO2)CCCCCC1 +COCCN(C1CCCC1)S(=O)(=O)c1c(C)noc1C +C=CCOC1CCN(C(=O)c2ccc(F)c(Cl)c2F)C1 +COc1ccc(C(C)=O)c(OCc2ccc(C(N)=O)cc2)c1 +CCCn1nnnc1NCc1ccc(Cl)cc1 +COC(=O)c1cc(-c2csc(NC(=O)CC3CCCO3)n2)c[nH]1 +Cc1ccc(COc2ccc(Cl)cc2CNn2nnnc2N)cc1 +CC(C)Oc1ccccc1NC(=O)c1ccncc1 +COCC(C)NC(=O)C(NC(=O)Nc1ccccc1)C(C)C +COC(=O)CCNc1cc(Cl)cc(C(C)=O)c1 +CC(c1cccnc1)N(C)C(=O)CCNS(=O)(=O)c1cccnc1 +CC(=O)N1CCCC(Cc2cc(Nc3nc(C)cc(C)n3)ncn2)C1 +Cc1cccc(N2CCN(C(=O)c3cc4c([nH]c3=O)CCC4)CC2)c1 +CC(C)NC(=O)Cc1ccc(NC(=O)c2ccc3cncn3c2)cc1 +O=C(NCCC(=O)N1CCCc2ccccc21)c1c(F)cccc1F +O=C(Cc1cccc(OC(F)F)c1)N1CCOCC1C1CC1 +CC(=O)NC(C)C(=O)N1CCCCC1c1nccs1 +C=CC1NCCc2c(Br)cc(C)cc21 +Cc1cc(COC(=O)COc2ccc3c(c2)CCC(=O)N3)on1 +O=C(NCc1ccc(N2CCCCC2=O)cc1)NCc1cccnc1 +Cc1ccc(C(N)=O)cc1NCC(=O)N(C)C1CC1 +Cc1cnc(C(=O)NC(C)c2ccccc2F)cn1 +COc1ccc(C(=O)NCc2noc(C)n2)c(OC)c1 +Cc1[nH]ncc1CCCNC(=O)CCC1Cc2ccccc2NC1=O +Cc1nc(-c2nnc(NC(=O)c3cccc4ccccc34)o2)cs1 +O=C(CCc1ccccc1F)N1CCC(O)CC1 +CCCCNC(=O)NCc1c(CC)noc1CC +O=S(=O)(CCc1ccccc1)NCC1(c2ccc(F)cc2)CC1 +C#CCN1C(=O)C2(CCN(C(C)=O)CC2)Nc2ccccc21 +Cc1cccc(NC(=O)Cn2c(C)ncc(C(=O)NC3CC3)c2=O)c1 +Cc1cccc(-n2ccnc2SCC(=O)N2CCNC(=O)C2)c1C +CCN(CC)C(=O)c1ccccc1NC(=O)C(C)Oc1ccccc1 +COc1cccc2sc(NC(=O)CCc3cnn(C)c3)nc12 +N#CCCN(CCC#N)C(=O)CNc1cccc2ccccc12 +O=C1CN(C(=O)C2CCCN(c3cccnn3)C2)CCN1 +COCCNc1ncnc(Nc2ccc(NC(C)=O)cc2)c1N +CC(C)c1nc(CC(=O)Nc2cccnc2-n2cccn2)cs1 +CCCNC(=O)C1CCCN(Cc2cnc(-c3ccsc3)s2)C1 +CCc1nnc(CNC(=O)c2cc(C3CC3)n[nH]2)s1 +O=C1CC(C(=O)n2cccc2)CN1c1ccccc1Cl +COc1ccnc(NC(=O)CCC(=O)c2ccc3c(c2)CCC3)c1 +O=S(=O)(c1ccccc1C(F)(F)F)N1CCOCC1C1CC1 +CCn1c(=O)n(CC)c2cc(N3CCCC3)c(NC(=O)NC)cc21 +COC(=O)c1sc(NC(=O)Cc2coc3cc(C)ccc23)nc1C +CN(Cc1ccn(C)n1)C(=O)C12CC3CC(C)(CC(C)(C3)C1)C2 +COc1ccccc1C(O)CNC(=O)c1ccco1 +COc1ccc(-c2nc(CN3CCNC(=O)C3)c(C)o2)c(C)c1C +Cc1noc(CNS(=O)(=O)c2cccc(C(F)(F)F)c2)n1 +O=C(NCCCNC(=O)c1ccco1)c1cccnc1 +CC(C)(C)OC(=O)NCC1CCN(C(=O)c2ccc(F)cc2F)C1 +CCC1CN(C(=O)CCC(=O)N(CC)CC)c2ccccc2O1 +COc1ccc(NC(=O)c2cccnc2N2CCCC2)c(OC)c1 +Cc1cc(N2CCN(c3ccccc3O)CC2)nc(-c2cccnc2)n1 +CCc1ccc(C(C)NC(C)C(=O)N2CCCC2)cc1 +COc1ccc(F)cc1NC(=O)N1CCN(c2nccs2)CC1 +CC(C)c1ccc(CNC(=O)c2nc3cccnc3n(C)c2=O)cc1 +N#Cc1cc(F)ccc1CN1CCN(c2nccs2)CC1 +COc1ccccc1CNC(=O)C1CCN(C(=O)OC(C)(C)C)C1 +CC(C)c1ccc(CCCC(=O)N2CCC(O)CC2)cc1 +COc1cccc(N2Cc3nn(C(C)C)c(=O)n3C2=O)c1 +N#CCn1cccc(OCc2ccc(F)cc2)c1=O +N#Cc1ccc(NCC2CCN(c3ccc(C#N)cn3)C2)nc1 +Cc1cc(C)c(CNC(=O)c2[nH]nc(C)c2Br)c(=O)[nH]1 +CCN(CCO)C(=O)Nc1cccc(C(=O)N2CCCC2)c1 +COc1ccc(C(=O)Nc2nnn(C)n2)cc1OC +COc1ccc(Br)cc1Nc1ncc(N)cn1 +Cc1csc(C2CCN(C(=O)c3scnc3C3CC3)CC2)n1 +CC(C)NC(=O)c1csc(-c2cccs2)n1 +COc1ccc(-c2noc(C(=O)N3CCCC3)n2)cc1OC +O=C(Cc1ccccc1)NCCC(=O)Nc1ccc(F)c(F)c1 +Cc1cc(C(N)=O)ccc1NC(=O)C1CCCN1c1nccs1 +O=C(c1ccc2c(c1)OCCO2)N1CCCC1Cn1cccn1 +Cn1ccc2c(-c3ccccc3C(N)=O)ccnc21 +CCCn1nnc2sc(-c3ccccc3)cc2c1=O +CCn1cc(NC(=O)C2CCC(=O)N2Cc2ccc(C)o2)cn1 +O=C(Cc1noc2ccccc12)Nc1nc(-c2cccnc2)cs1 +CC(=O)Nc1ccc(C)c(NC(=O)c2ccco2)c1 +COc1ccc(CCN(C)C(=O)C2CCC(F)(F)CC2)cc1OC +O=C(NCC(=O)OC1CCCCC1)NCc1ccco1 +O=C1CC(C(=O)NC2CCCC2)C(C(=O)NC2CCCC2)C1 +CN1CC(C(=O)NCCc2ccc(Br)cc2F)CC1=O +CCCCCNC(=O)Nc1cc(-n2cnnn2)ccc1F +CC(C)OCCC(=O)N(C)c1cccc2ccccc12 +CC(=O)N1CCCc2cc(C(=O)N3CC(C)(C)C3(C)C)ccc21 +CCOc1ccccc1C(=O)Nn1cnc2ccccc21 +Cc1ccccc1C(=O)OCC(=O)N(C)c1ccc(F)cc1 +CC1(C)Cc2c(sc3[nH]c(=O)n(Cc4ccco4)c(=O)c23)CO1 +C=CCNC(=O)CSc1nccc(-c2ccc(F)cc2)n1 +COc1c(N)cc(-c2cc(C(=O)OC(C)C)[nH]n2)c(O)c1OC +CCc1noc(CC)c1CC(=O)Nc1ccc(Cn2cccn2)cc1 +O=C(NCCNc1ncccn1)c1ccc(N2CCOCC2)nc1 +CCOC(=O)COc1cccc(NC(=O)c2ccc(C#N)cc2)c1 +Brc1cnc(-c2cccnc2)nc1C1CC1 +CC(c1ccc(F)cc1)n1c(-c2cc(C3CC3)n[nH]2)n[nH]c1=O +COC(=O)c1cc(NC(=O)C2CCC2)ccc1F +CN(Cc1cnn(C)c1)C(=O)Nc1ccc(F)c(C(F)(F)F)c1 +CC1CCCCN1C(=O)CCSc1ccccn1 +Cn1ccc(NC(=O)CNC(=O)NCc2ccccc2)n1 +CC(=O)Nc1cccc(OC(=O)N2CCOCC2)c1 +N#CCCN(Cc1ccco1)C(=O)c1ccc(N2CCCC2=O)cc1 +O=C(Nc1nccs1)C1CCCN(C(=O)Nc2cccs2)C1 +Cc1nc(NC(=O)N2CCC(c3nnc4n3CCC4)CC2)sc1C +CNC(=O)CNC(=O)Nc1c(C)cc(Br)cc1Cl +O=C(Nc1ccn(CC(O)CO)c(=O)n1)c1ccccc1 +CCOC(=O)Cn1c(-c2nonc2NC(=O)CC)nc2ccccc21 +CCS(=O)(=O)NCCSc1nnnn1-c1ccc(C)cc1 +Cc1noc(C(C)OC(=O)C2CC2(Cl)Cl)n1 +CC(=O)c1ccc(OCC(=O)NCc2ccc(C)c(F)c2)cc1F +CCC(CC)NC(=O)NCc1ccccc1-n1ccnc1 +CN(C(=O)c1ccc2c(c1)CCC(=O)N2)c1ccc(F)c(F)c1 +CSc1ccc(C2CC(=O)NC3=NC(N)=NC(=O)C32)cc1 +O=C(c1cccnc1)N1CCN(Cc2ccccc2)CC1 +COCc1ccc(CN2CCc3nnc(-c4ccccc4)n3CC2)o1 +Cc1ccc(F)cc1C(=O)Nc1cc(-n2cnnn2)ccc1F +COc1ccc(F)cc1NC(=O)c1cccc2ccc(C)nc12 +COCc1nc(CN2CCOC3(CCCC3)C2)cs1 +COCc1ccccc1C(=O)Nc1cc(NC(=O)C(C)C)ccc1C +Cc1cc(NC(=O)CCc2ccc(Br)cc2F)[nH]n1 +O=C(Cn1c(C2CC2)nc2ccccc21)N(Cc1ccccn1)C1CC1 +CC(Oc1ccc(F)cc1)C(=O)N(C)CC(N)=O +Fc1cccc(N2CCCC2c2cccc3c2OCCO3)n1 +N#CC(C(=O)CSc1n[nH]c(N)n1)c1nc2ccccc2[nH]1 +Nc1cnc(CCOc2ccc3c(c2)OCO3)nc1 +O=C(c1ccccc1Cl)N1CCN(Cc2ccccc2)CC1 +COCC(C)NC(=O)c1nccnc1-c1nc2ccccc2s1 +C=Cn1c(N(CC)CC)nc2c1c(=O)[nH]c(=O)n2C +COc1ccc(S(=O)(=O)Cc2noc(C3CC3)n2)cc1 +Cc1cc(NC(=O)CN(C)S(C)(=O)=O)n(C)n1 +CC(C)CC(=O)Oc1cccc(NC(=O)CN2CCCC2=O)c1 +Cc1nc2cc(NC(=O)c3cnn(-c4ccccc4C)c3C)ccc2o1 +CCc1nc(C)c(C(=O)N2CCN(CCOc3ccccc3)CC2)o1 +O=C(Nc1ccc(F)cc1Br)C1CCC1 +CC1CC(C)CN(S(=O)(=O)Nc2cn[nH]c2)C1 +CNC(=O)C1CC1c1ccc(OC(F)(F)F)cc1 +CC(C)(C)OC(=O)NC(Cc1ccccc1)C(O)CO +Cc1nn2c(CNC(=O)c3ccc(N(C)C)cc3)c(C)nc2s1 +COCCN1CC2(CCCN(c3cc(C(N)=O)ccn3)C2)CCC1=O +CC1CCCC(CNC(=O)NC(CCO)c2ccccc2)C1 +c1cncc(CSc2ccc(-c3ccc4c(c3)OCO4)nn2)c1 +CC(C)Cc1nnc(NC(=O)N(C)CCc2ccc(F)cc2)s1 +Cn1c(=O)c2cc(C(=O)NCCCO)cnc2n(C)c1=O +O=S(=O)(Nc1cccc2n[nH]nc12)c1ccccc1 +CCN1CCN(C(=O)COc2ccc(C#N)cc2)CC1 +COc1cc(C)c(C(=O)NC2CCC(O)CC2)cc1OC +Cc1oc(-c2cccs2)nc1C(=O)Nc1cccnc1 +Nc1cccc2cc(S(=O)c3ccccc3)cnc12 +COc1ccc(C2NCCN(C)C2=O)cc1C(C)C +CCC(=O)Nc1cc(NCC(=O)N(C)C)ccc1C +Cc1ccc(CNC(=O)Nc2ccc(C#N)cc2)c(N(C)C)c1 +CC(C)Oc1ccc(C(=O)NCCNC(=O)c2ccco2)cc1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(C2CC2)on1 +CCn1nccc1CNC(=O)Nc1cccc2ccccc12 +O=C(Nc1ccccc1O)c1cn2cccnc2n1 +Nc1nc(CN2CCN(Cc3cccs3)CC2)nc2ccccc12 +Cc1cc(C(=O)NCC(=O)Nc2ccc(C)c(C)c2)n(C)n1 +N#CC1(C(=O)NCc2ccc(Oc3cccc(F)c3)nc2)CCCC1 +Cn1nncc1CN1CCCC(c2nccs2)C1 +CCOc1ccc(CC(=O)Nc2ccc(N)cc2C)cc1 +CCNC(=O)c1ccc(NC(=O)NC(C)(C)CO)c(C)c1 +OC(CNCc1ccccn1)c1ccc2ccccc2c1 +CC(=O)Nc1sc2c(c1C(=O)N1CCOCC1)CCCC2 +CN(Cc1ccc2c(c1)OCCO2)C(=O)c1c[nH]c2ccccc12 +COc1ccccc1CC(=O)Nc1ccccc1N1CCCC1 +O=C(NCC(O)Cc1ccccc1)NC1CC1c1cccc(Cl)c1 +CC1(CNC(=O)c2cccc(-c3ccoc3)c2)CCCCC1O +O=C(CNC(=O)COc1ccccc1O)NCc1ccco1 +COc1ccc(Br)c(CNC(=O)c2nccnc2N)c1 +Cc1ccc(F)c2c1N(C(=O)c1scnc1C)CCC2 +CCOC(=O)Nc1cc(N2CCCS2(=O)=O)ccc1OC +CCn1nnc2cc(C(=O)NCc3cc4ccccc4o3)ccc21 +Cc1ccc(C)c(OCC(=O)Nc2ccc(N)cn2)c1 +O=S(=O)(Cc1nc(-c2ccc(F)cc2)no1)c1ccccc1 +O=C(CCSc1ccccn1)Nc1cccc(C(F)(F)F)n1 +C=CCCC(=O)N1CCc2[nH]nc(-c3ccc(F)c(F)c3)c2C1 +CC(c1ccccc1)N(C)C(=O)CCc1nc(-c2ccsc2)no1 +CC1(C)CCCN1C(=O)NC1CCN(c2c(F)cccc2F)C1=O +Cc1cc(Nc2ccccn2)nc(C2CCCCN2S(C)(=O)=O)n1 +COC(=O)C(NCc1cccc(N2CCCC2=O)c1)c1ccccc1 +CNS(=O)(=O)c1cc(NCC2CCCC2)ccc1C +Cc1cnn(CCC(=O)NC2CCC(c3ccccc3)CC2)c1 +COC(=O)N1CCC(NC(=O)c2cc(Cl)ccc2Cl)CC1 +NC(=O)CCCNC(=O)C1(c2ccccc2)CCC1 +CN1CCN(S(=O)(=O)c2ccc(NC(=O)c3ccco3)cc2)CC1 +O=C(NCC(O)c1ccco1)c1ccc(SC(F)F)cc1 +Cc1nc(-c2cccc(NC(=O)NC(C)(CO)C3CC3)c2)oc1C +Cc1csc2cc(C(=O)NCc3ccc(F)cc3)cnc12 +CCOCCC(=O)N1CCC(c2nnc(Cn3cncn3)n2C)CC1 +CC(C(=O)N1CCCC1)N1CCN(C(=O)C2CCCOC2)CC1 +CC(C)(CNC(=O)C1(C#N)CCCC1)c1ccncc1 +COCc1cccc(C(=O)NC(C)c2ccc3c(c2)NC(=O)CO3)c1 +O=C(c1cnc2ccccn2c1=O)N1CCCC2(CCCCCC2)C1 +COCCOc1nc(C)nc(NC2CCCCC2C)c1N +Cn1nccc1CNC(=O)Nc1ccc(F)c(C(N)=O)c1 +Cc1ccccc1CNC(=O)c1ccc2c(c1)CCC2 +CC(NC(=O)Nc1nncs1)c1ccc(Cl)cc1Cl +CC(C)c1noc(CCNC(=O)C2CCOc3ccccc3C2)n1 +CCn1cc(NC(=O)c2n[nH]c3ccccc23)cn1 +Cc1ccc2[nH]c(=O)c(CN(CCO)C(=O)c3ccco3)cc2c1 +COc1cc2c(cc1OC)CN(C(=O)c1ccc(N(C)C)cc1)CC2 +CN(CC(=O)NCC(F)(F)F)S(=O)(=O)c1cccnc1 +COc1ccc(-c2cnnc(NCCOc3cccnc3)n2)cc1 +COc1ccc(NC(C)=O)cc1NC(C)C(=O)N(C)c1ccccc1 +Cc1n[nH]c2ncc(NC(=O)c3cc4occc4[nH]3)cc12 +C#CCNC(=O)c1ccccc1COc1ccccc1 +O=C1CN(C(=O)CCc2ccc3c(c2)OCO3)c2ccccc2N1 +FC(F)CN(Cc1ncccc1C(F)(F)F)C1CC1 +Cc1cnc(NC(=O)Cc2csc(Cc3ccccc3)n2)s1 +O=C1CCC(COC(=O)c2ccc(COc3ccc(F)cc3)o2)N1 +C#CCN1C(=O)C(C)(CC)Nc2cc(Cl)ccc21 +Cn1nnnc1SCC(=O)NCCc1ccc(F)cc1 +O=C(CCn1cccn1)N(CCO)C1CCCCC1 +CC(C)(C)Oc1cc(CNC(=O)c2ccsc2)ccn1 +Cc1ccc(C)c(NC(=O)COc2cc(C)on2)c1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)NC1CC1 +Cc1ccc(CSc2nnc(C(F)(F)F)n2N)cc1 +Cc1noc(C)c1CCC(=O)Nc1cc(C(C)(C)C)nn1C +Cc1ccc(NC(=O)Cc2c(C)nc3nc(N)nn3c2C)cc1F +COc1ccc(C(=O)CC2(O)C(=O)Nc3ccc(C)cc32)c(OC)c1 +CC(=O)N1CCCC(C(=O)N2CCN(c3cc(C)nc(N)n3)CC2)C1 +C=CCN1CC2=C(C1=O)C(c1ccc(F)cc1)NC(=O)N2C +FC(F)(F)Oc1ccc2c(c1)CCNC2c1ccccn1 +CCNC(=O)c1ccc(CNC(=O)c2ccnc(SC)c2)cc1 +O=C(NCC1CCC1)c1ccc(Cn2nnc3ccccc32)cc1 +CC(c1cc2ccccc2o1)N(C)C(=O)Nc1cnn(C)c1 +CCOc1ccc(C(=O)Nc2ccccc2N)cc1 +CCC(CC)NS(=O)(=O)c1ccc(OC)c(OC)c1 +CCOc1ccc(C(C)NC(=O)c2ccc(O)c(Cl)c2)cc1OC +Cc1cc(C)n(S(=O)(=O)c2cc(Cl)ccc2C)n1 +CN(CCc1ccccn1)C(=O)c1cc(Br)ccc1F +CC(NC(=O)NCCCn1cncn1)c1ccc2c(c1)NC(=O)CO2 +C#CCCN1CCN(C(=O)CNC(=O)Cc2cccc(F)c2)CC1 +O=C(Nc1ccc(O)c(Cl)c1)c1cccc(CN2CCOCC2)c1 +N#Cc1c[nH]c(C(=O)N2CCN(c3cc(N)ncn3)CC(O)C2)c1 +CC1Cc2ccccc2N1c1nccc(-c2ccncc2)n1 +O=C(c1ccc(O)c(Cl)c1)N1CCN(c2nccs2)CC1 +O=C(NCc1cccnc1-c1ccccc1)c1ccc2c(c1)OCO2 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cccc(NC(C)C)c1 +C=CCn1cnnc1SCc1cc(=O)n2nc(CC)sc2n1 +Cc1cc(Br)cc(C)c1NC(=O)C1CC1C +Cc1noc(C)c1COc1ccc2ccc(=O)oc2c1 +COc1c(Cl)cccc1NC(=O)N1CCC(n2cncn2)CC1 +COc1c(F)cc(NC(=O)Cn2ccc(=O)n(C)c2=O)cc1F +Cc1cc(F)cc(S(=O)(=O)N(C)C2CCC(CO)CC2)c1 +O=C(c1n[nH]c2c1CCCC2)N1CCCC(O)(CO)CC1 +CCN(C)C(=O)c1ccc2c(c1)S(=O)(=O)N(CC)C2=O +COc1c(Cl)cc(Cl)cc1C(=O)NCCCO +CN(CCc1ccc(F)cc1)C(=O)NCc1ccc(O)cc1 +COc1cccc(Cc2nnc(NC(=O)c3ccc(=O)[nH]c3)s2)c1 +COc1ccccc1N1CC(C(=O)NCCC(C)C)CC1=O +CCn1c(C2CC(=O)N(CC(C)C)C2)nc2ccccc21 +COc1cccc(-c2nc3c(OC)cccn3c2C#N)c1 +CCCCN(CCO)C(=O)Nc1cccc(SC)c1 +COCCCNC(=O)Nc1cccc(-c2nc(C)cs2)c1 +CC(=O)NC(C)(C)c1noc(-c2cnc3c(cnn3CC(C)C)c2)n1 +CC(C)(C#N)NC(=O)CCCc1nc(-c2ccc(F)cc2)no1 +CN(Cc1ccc(Cl)cc1)C(=O)c1cc2occc2n1C +C=CCNC(=O)c1nccc2c(N)c(Br)ccc12 +O=C(COCC1CCOC1)Cc1ccccc1F +CCNC(=O)N(Cc1nccn1Cc1cccc(OC)c1)C1CC1 +COCC(=O)NC(C(=O)Nc1ccc(C)c(F)c1)C(C)C +Cc1ccoc1C(=O)N1CCc2ncnc(C3CC3)c2CC1 +Cc1ccc(-c2c(CO)nnn2-c2nnc(C(C)C)s2)cc1 +CCN(C(=O)c1nc2nccc(C)n2n1)c1cccc2ccccc12 +CN(C)C(=O)CNc1cc(Br)ccc1Cl +CN1CCN(C(=O)Cn2cnnn2)C(c2ccccc2)C1 +Cc1ccc(S(=O)(=O)N2CCCN(S(C)(=O)=O)CC2)s1 +CCOc1cc(C(=O)N2CCOC(C)C2)cc(OCC)c1OCC +COc1ccc(C(=O)NCCc2c[nH]c(-c3ccccc3)n2)cc1 +CC(C)OC(C)C(=O)N(Cc1ccncc1)Cc1ccc(O)cc1 +CC(C)(C)C(O)CCNC(=O)NCc1ccc(Cl)cc1 +COC(=O)c1sccc1NC(=O)CCn1cncn1 +COCCNc1nc(-c2c(C(C)C)oc(C)c2C)cs1 +O=C(NCc1ccccc1Cl)NCC1CCOC1 +CN(CCc1ccccn1)C(=O)Nc1nnc(-c2ccccc2)s1 +Nc1nncc(-c2ccncc2)c1C(=O)N1CCCCCC1 +CN(Cc1cnccn1)C(=O)NCC1(Cc2ccccc2)CCC1 +COC(=O)CC(NC(=O)c1ccccc1OC)c1cccs1 +CC(c1ccco1)N(C)Cc1nnc2n(C)c(=O)c3sccc3n12 +COc1ncccc1CNC(=O)NCc1cccnc1OC +CC(=O)N(Cc1ccc(NC(=O)C2CC=CC2)cc1)C1CC1 +CCOc1cccc(OCCN2C(=O)CNc3ccccc32)c1 +CC1CN(C(=O)Cn2nc(-c3ccc(F)cc3)oc2=O)CCO1 +COc1ccnc(N2CCN(C(=O)c3cccc4ccccc34)CC2)n1 +N#CCCC(NC(=O)C1COc2ccc(F)cc2C1)c1ccccc1 +O=C(NCC(Cc1cccc(F)c1)N1CCCC1=O)c1ccccn1 +CCOc1ccccc1NCc1cc(C#N)ccc1F +CCOC(=O)Cn1c(=NC(C)=O)sc2cc(C)ccc21 +COc1ccc(C(=O)Nc2ccccc2NC(=O)C2CCCO2)cc1 +Nc1ncc(Br)cc1C(=O)NCCCS(N)(=O)=O +CCC(C)Oc1ccc(NC(=O)CSc2nncs2)cc1 +Cc1nc(C2(NC(=O)CCCc3cc(F)ccc3F)CCCC2)no1 +CS(=O)(=O)N1CCCCC1C(=O)Nc1ccc2ncsc2c1 +O=C(C1CCOc2ccccc21)N(Cc1cccnc1)Cc1ccco1 +CC(C)NC(=O)c1nsc(C(=O)NCc2ccc(F)cc2)c1N +Cc1cc(=O)oc(C)c1C(=O)Nc1cccc(F)c1 +Cc1noc(C)c1CC(=O)NCCc1cccnc1 +CCN(Cc1cnn(C)c1)C(=O)c1c(C)c(C)nc2ccc(C)cc12 +Cc1csc(N(C)C(=O)c2ccccc2SCC(N)=O)n1 +Cc1ccc(CNC(=O)N(C)Cc2ccco2)cc1 +Cc1nc(C(C)(C)NC(=O)c2cccc(-n3cnnn3)c2)sc1C +CCN(CC(=O)NC(C)(C)C)C(=O)c1csnn1 +COC(=O)c1ccc(CN2CCN(c3ccc(OC)cc3)C2=O)cc1 +CCc1noc(CNc2ccc3ccccc3c2)n1 +CC(=O)N1CCc2cc(C(=O)NCc3ccc(C)s3)ccc21 +Cn1cc(CN2CCOC3C(CNC(=O)c4ccco4)CCC32)cn1 +Cc1nc(C(C)Nc2nc(C3CCCC3)nc3c2cnn3C)n[nH]1 +Fc1cccc(C2c3cccn3CCCN2Cc2cccnc2)c1 +CC(=O)Nc1ccc(NC(=O)NC2(c3ccc(Cl)cc3)CC2)cc1 +CC(=O)c1ccccc1NC(=O)C(C)Sc1nncn1C1CC1 +O=C(NCCc1cc(F)cc(F)c1)c1ccc(OCC(F)F)nc1 +Cc1ccc2c(c1F)CCNC2c1ccc(O)cc1 +COCCN(CC(C)C)C(=O)NC1CCc2ccccc21 +Cc1cc(C)n(CCCNC(=O)c2cc(F)ccc2F)n1 +CCN(C)c1ccc(C(=O)Nc2nc3c(s2)CCC3)cc1 +Cc1ccc(CC(=O)Nc2nc(-c3ccc(F)c(F)c3)cs2)cn1 +Cc1cc(C(=O)Nc2nnc(Cc3cccs3)o2)on1 +Cc1ccc(C(=O)CCC(=O)NCc2cnc(C)s2)cc1 +Cc1ccsc1C(=O)OC(C)C(=O)Nc1ccnn1C(C)C +COc1ccc(OC)c(NC(=O)Cc2coc3ccc(F)cc23)c1 +CC(C)C(=O)N1CCN(c2nnc3ccc(Cl)cn23)CC1 +O=C(Cn1cnc2ccccc21)Nc1cccc(C(F)(F)F)c1 +CC(O)(CNC(=O)Nc1ccccc1F)c1ccc2c(c1)OCO2 +Cc1cccc2nc(C(=O)NC(C)c3cccc(C(F)(F)F)c3)cn12 +Cn1ccc(NC(=O)CCc2ncc(-c3ccccc3)o2)n1 +O=S1(=O)CCCN1Cc1nn(-c2ccc(F)cc2)c2c1CCC2 +CC(=O)Nc1nc(C(=O)N2CCC(Cc3ccccc3)CC2)cs1 +Cc1nn(C)c(C)c1OCc1c(F)cccc1F +Cc1occc1C(=O)NCCOc1cccc(Cl)c1 +Cc1nccn1-c1ccc(CNc2cccc(F)c2C#N)cc1F +Cn1cc(NC(=O)Nc2cc(N3CCCC3=O)ccc2Cl)cn1 +CSc1ncccc1C(=O)OCC(=O)Nc1ccc(C)cc1C +CCN(Cc1ccccc1)C(=O)Nc1ccncc1 +CCn1c(-c2cc(OC)ccc2OC)ccc(CC#N)c1=O +CNc1ncc(C(=O)NCC2CCCCC2)cc1Cl +CC(=O)c1cc(Cl)cc(N2CCN(C(C)=O)CC2)c1 +CC(NC(=O)c1cnns1)C(C)(C)c1ccccc1 +CC(NC(=O)c1nccnc1N)c1ccccc1Br +CCN1CC(C(=O)Nc2cc(C)nn2Cc2ccccc2)CC1=O +COc1ccc(C(=O)NC2CCCN(c3ccccc3)C2=O)nn1 +CC1CN(C(=O)CCc2ccc3ccccc3n2)CC(C)O1 +CCn1c(C)cc(C(=O)N(C)Cc2nc(-c3ccncc3)no2)c1C +O=C(c1ccc2nc(-n3cccc3)sc2c1)N1CCCC1CO +COc1cc(NC(=O)N(C)Cc2ccc(F)cc2)ccc1NC(C)=O +Cc1cc(C)c(CNS(=O)(=O)CC2CCOCC2)c(C)c1 +COC(=O)C(C)(C)c1ccc(NCc2cn3cccnc3n2)cc1 +CC(=O)N(C)c1ccc(NCC(=O)Nc2cccc(Cl)c2)cc1 +O=C(Cn1nnc2ccccc2c1=O)OCc1ccccc1Cl +CCCCc1noc(C(C)Nc2cccc(CO)c2)n1 +CCNS(=O)(=O)c1cc(C(=O)NC)sc1C +CC(NC(=O)Cc1ccsc1)c1cccc(N)c1 +Cc1cccc(C(=O)N(CC(F)(F)F)C2CCOCC2)c1 +CC1(C)CCCN1C(=O)Cn1cnc2ccccc2c1=O +O=C(CCc1ccc(-c2ccccc2F)o1)NCCO +N#CCOc1cc(C(=O)NC2CCCCCC2)ccc1N +O=C(NCCOc1ncccc1Cl)c1scnc1C1CC1 +O=C(Nc1ccc2c(c1)COC2)C1(Cc2ccccc2)CC1 +Cc1[nH]nc(-c2ccccc2)c1NC(=O)C1CCC1 +COc1ccccc1CC(=O)N(C)c1ccccc1 +Cc1cc(=O)n(CC(=O)N(C)Cc2csc(C(C)C)n2)nc1C +CC=CCOC(=O)C(C)Oc1ccc(OC)cc1 +CS(=O)(=O)N1CCC2C1CCN2C(=O)c1ccncc1F +CCn1nnnc1SCc1cccc2cccnc12 +C#CCNC(=O)NCc1ccnc(OCC(F)(F)F)c1 +O=C(Cc1nnc(-c2ccccc2)o1)NC1CCCCC1 +CSc1ccccc1C(=O)Nc1ccccc1C(=O)NC(C)C +O=C(Nc1ccc2c(c1)OCCO2)c1ccnc2ncccc12 +CC(=O)c1ccc(NC(=O)C2CCCN2C(C)=O)cc1C +CC(C)NC(=O)N1CCc2nc(NC(=O)C3CC3)sc2C1 +Cc1nc(C(N)c2ccc(Cl)c(Cl)c2)sc1C +CN1CCOC2CN(CCC(=O)Nc3cccc(F)c3)CC21 +CC(NC(=O)c1ccccc1Cl)C(=O)Nc1cccnc1 +Cc1cscc1C(=O)Nc1ccc(CN2CCOCC2)cc1 +CCOC(=O)CCC(=O)Nc1ccc(C(N)=O)cc1 +CC=CCn1c(C(=O)N2CCOCC2)cc2sccc21 +COCC(C)NC(=O)c1ccc(N2CCOC2=O)cc1 +CC(=O)NC1(c2noc(C3CC4CCC3C4)n2)CCCC1 +CCn1nc(C(=O)Nc2nc3ccc(C)cc3s2)cc1C +Cc1cccc(S(=O)(=O)C(C)c2nc(C3CC3)no2)c1 +O=C(Nc1ccccc1COc1ccccc1)c1cnn2c1OCCC2 +CCc1ncc2c(n1)CN(C(=O)CCNC(=O)c1ccccc1F)C2 +CCCC(C)C(=O)NCC(=O)Nc1c(C)cccc1C +CN(C)C(=O)C1(C)CN(CCc2ccccc2)CCO1 +CC1Nc2ccccc2N(Cc2ccc(C#N)cc2)C1=O +CCc1ccc(C(=O)OCCN2CCOC2=O)o1 +COC(=O)N1CCCN(C(=O)Nc2ccc3nc(C)sc3c2)CC1 +COC(=O)c1n[nH]c(N)c1-c1cc(Cl)ccc1OC +Cc1nn(C)c(C)c1CC(=O)N1CCCc2cc(Cl)cc(F)c21 +CCCN(CCO)c1ccc(C(=O)Nc2ccccc2)nn1 +COc1ccc(S(=O)(=O)Nc2cn[nH]c2)c(C)c1F +COc1ccc(Cl)c(NC(=O)N2CCCC2)c1 +Cc1cc2cc(C#N)c(NCCCNC(=O)C3CC3)nc2cc1C +CCOc1cc2c(cc1CNC(=O)c1cccc(F)c1)OC(C)C2 +COc1ccc(NC(=O)c2ccc(OC)c(OC)c2)cc1 +CC(O)c1cccc(-c2cc(NCc3cccnc3)nc3[nH]ccc23)c1 +CC(CO)NC(=O)c1ccc(Br)cc1F +Cc1nc(COc2cccc(C(=O)N3CCOCC3C3CC3)c2)no1 +Cc1nc(-n2cccc2)sc1C(=O)Nc1n[nH]c(CC(C)C)n1 +C=CCN(Cc1ccccc1)C(=O)NC1CCC2(CC1)OCCO2 +CCCCNC(=O)NCCCn1ncc2ccccc21 +CNC(=O)Cc1ccc(NC(=O)c2cccc(OC)c2F)cc1 +CC(=O)Nc1cccc(NCC(=O)N2CC(C)OC(C)C2)c1C +O=C1CCN(CC(=O)c2ccc(Cl)cc2)CC1 +COc1cccc(OC)c1C(=O)N(C)C(C#N)c1cccnc1 +Cc1ccc(N2C(=O)C(C)(C)CS2(=O)=O)cc1C +COc1ccc(C(=O)Nc2cccnc2-n2ccnc2C)cc1OC +CC(C)S(=O)(=O)NC1CCC2(CC1)OCCO2 +Cn1cc(CCC(=O)NC2(C)Cc3ccccc3C2)cn1 +CC(=O)N(C)CC(=O)NCC(C)(C)c1ccc(Cl)cc1 +CCC(Oc1ccccc1C)C(=O)Nc1ccc(-n2cccn2)nc1 +COc1ccc(OC)c(CC(=O)Nc2nccs2)c1 +CCc1cnc(C)nc1NC(CC)c1cnn(C)c1 +CC(Oc1cccc(Br)c1)C(=O)NCc1cccnc1 +CCCCN(C)Cc1cc(=O)c(O)cn1CCO +C#CCNC(=O)NCc1cn(-c2ccccc2)nc1-c1ccccc1 +CCC1CCC(NC(=O)CCOc2ccccc2OC)CC1 +Cc1ccn2ncc(C(=O)NCC(=O)NC3CC3)c2c1 +Cc1ccc(C(=O)N2CCN(C(=O)c3cc4ccccc4o3)CC2)cn1 +CCNc1c(F)cccc1C(=O)NC(C)(C)CC +COc1ccc(NC(=O)c2cncc(Br)c2)cc1N +CC(O)(CNS(=O)(=O)c1ccc(F)cc1F)C1CC1 +CN(CCCNC(=O)c1cc(F)cc2[nH]cnc12)c1ccccc1 +COc1ccc(C(=O)OCc2nc(-c3cccc(Cl)c3)no2)nn1 +COC(=O)CN1CCN(c2ccc3nnnn3n2)CC1 +CC(=O)c1c[nH]c(C(=O)NCCC(=O)NCc2ccccc2)c1 +O=C1CC2C(=O)NCCN2C(Nc2ncccn2)=N1 +COC(=O)N1CCC(CNS(=O)(=O)c2cccnc2)CC1 +Cc1cc(N2CCC(Oc3cccnc3)CC2)n2nccc2n1 +O=C(CN1CCN(Cc2nnc(C3CC3)o2)CC1)N1CCCCC1 +C=CCn1c(=O)n(CC=C)c(=O)n(CC(F)(F)F)c1=O +CC(C(=O)NCCc1cn(C)c2ccc(Cl)cc12)N1CCOCC1 +CNS(=O)(=O)c1cccc(NC(=O)CC2CCCO2)c1 +Cn1cc(C(=O)Nc2ccccc2F)c(=O)c2cccc(Cl)c21 +C=CCN1CCN(C(=O)NCc2ccc(C)cc2)c2cccnc21 +CC(COc1ccccc1)NC(=O)c1cccnc1 +O=S(=O)(C1CC1)N1CC(c2nc(Cc3ccccc3)no2)C1 +O=C(c1ccnnc1)N1CCCC2(CC(Oc3ccccc3)CO2)C1 +CC(C)c1nccn1Cc1cccc(NC(=O)NCc2ccncc2)c1 +CC(C)C(=O)N1CCC(n2nc(-c3cccs3)oc2=O)CC1 +CCn1c(C)cc(C(=O)NC(C)c2ccc3c(c2)OCO3)c1C +O=C1N(C2CCCCC2)CCCC12CCN(c1cnccn1)C2 +c1nnc(-c2ccc(OCCOCC3CCCO3)cc2)o1 +C=CCN1CCN(C(=O)Nc2cc(C)ccc2OC)c2cccnc21 +Cc1noc(COC(=O)c2ccc(-c3ccc(F)cc3)o2)n1 +COc1cc(C(=O)Nc2ccc(C)cn2)ccc1OCC(N)=O +CCOC(=O)CNC(=O)NC1CCCc2ccccc21 +O=C1CCc2cc(C(=O)NCCNc3ncccn3)ccc2N1 +N#Cc1cccc(OCC(=O)Nc2cc(Cl)ccc2C#N)c1 +Cc1ccccc1CCC1CCCN(C(=O)Cn2cccn2)C1 +Cc1noc(NC(=O)CNC(=O)OC(C)(C)C)n1 +N#CCc1cc(C2CC2)n(-c2ccc(C(F)(F)F)cc2)n1 +C=CCNC(=O)c1nc(N2CCOCC2)ncc1Cl +Cc1ccccc1OCCSc1n[nH]c(N)n1 +O=C(NCCc1cccs1)c1ccc2cc[nH]c2n1 +O=C(CSc1ccc2c(c1)OCCCO2)Nc1ccc(F)cc1 +O=C(c1cccc(-c2cccc(=O)[nH]2)c1)N1CCCC1 +COc1cc(NCCc2c[nH]c3ccccc23)nc(C)n1 +CCCc1noc(CSc2nnnn2C(C)C)n1 +Cc1oncc1C(=O)NCC(O)c1ccc(N)cc1 +CC(=O)NC(C)C(=O)OC(C)c1ccc(C(C)(C)C)cc1 +COc1ccc(Cc2nc3scc(N)n3n2)cc1OC +COc1ccccc1C(C#N)C(=O)c1occc1C +COc1ccc(NC(=O)C(C)n2c(C)cc(C)nc2=O)cc1Cl +O=C(NCCNc1cc(N2CCOCC2)ncn1)Nc1ccccc1 +CC(C)c1nc2ncnn2c(N)c1-c1cccc(Cl)c1 +C=CCN1C(=O)c2ccccc2C1C(=O)NC1CCCCC1 +CC(C)Cn1c(CCNC(=O)c2cccc(C#N)c2)nc2cccnc21 +COc1ccc(Cl)cc1S(=O)(=O)N(C)CCCO +COc1ccc(C(=O)N2CCN(C(=O)CCn3cnnn3)CC2)cc1 +CCNC(=O)C(C)NC(=O)Nc1cccc(N)c1 +N#CCOc1cccc(CC(=O)N2CCC3(CCCC3)CC2)c1 +CCOc1ccc(Nc2ccc(S(=O)(=O)N3CCCC3)cn2)cc1 +O=C(COc1ccccc1)N1CCN(CCO)CC1 +O=C(Cn1cnc2ccccc2c1=O)Nc1nc2ccccc2s1 +CN(Cc1ccccc1)C(=O)c1ccc(C(N)=O)nc1 +O=C(CSc1ccccn1)Nc1cc(Cl)ccc1F +CCn1nc(-c2ccc(Cl)cc2)nc2c(=O)n(C)c(=O)nc1-2 +Cc1cccc(-c2nc3sc4c(n3n2)CCNC4)c1 +Cc1ccc(NC(=O)NCc2nncn2C(C)C)s1 +CN(C)S(=O)(=O)c1ccc(C(=O)N=c2[nH]c3ccccc3[nH]2)cc1 +CC(C)c1nc(C(C)NC(=O)c2cccc(-n3cccn3)n2)cs1 +O=C(c1cnccn1)N1CC2CN(c3ncc(F)cn3)CC2C1 +Cc1cnn(CCC(=O)NC2CC2c2cccc(Cl)c2)c1 +COc1cccc(C(=O)NCC(O)c2ccoc2)c1OC +CC(CC1CCCO1)Nc1nnc(C(F)(F)F)s1 +O=C(Nc1cc(F)c(F)c(F)c1)c1ccccc1-n1cnnn1 +COc1cc(C)c(Cl)c(C)c1-c1nccnc1C#N +Cc1cc(NC(=O)NCC(=O)Nc2ccccc2)c2ncccc2c1 +Cc1cc(-c2nc3c([nH]2)CC(C)(C)CNC3=O)no1 +Cc1nn2c(-c3ccccc3)nc3ccccc3c2nc1=O +COC(=O)C1CC(OC)CCN1CCN1CCCC1=O +CCNC(=O)CNC(=O)c1cc(Br)ccc1F +Cc1ccc(-c2cc(N)c(=O)n(CC(C)C)n2)cc1C +Cc1ccc(Br)c(NCc2noc(-c3ccoc3)n2)c1 +CN(C)c1cccc(C(=O)Nc2cccnc2N2CCOCC2)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccn2cncc2c1 +O=C(NC1CNCc2cccc(Cl)c21)C1CC1 +Cc1noc(C)c1CC(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +CCOC(=O)C(C)(C)n1nnc(C(C)=O)c1-c1ccccc1 +COc1ccc(C(O)(c2ccccc2)c2cc[nH]c(=O)c2)cc1 +O=c1[nH]ncc(NCCOc2cccc(Cl)c2)c1Cl +Cc1cnn(CC2CCCN2C(=O)COc2ccc(C(N)=O)cc2)c1 +Cc1csc(CCNc2ccccc2N(C)C)n1 +CN(CC(=O)Nc1cccc(F)c1)C(=O)C1CCCCC1 +CC1CCc2ccccc2N1S(=O)(=O)c1ccc2c(c1)OCCO2 +Cc1cccnc1NC(=O)Cc1noc2ccccc12 +Cc1ccc(N2CC(C(=O)Nc3nncs3)CC2=O)cc1F +CC(C)CCNC(=O)N1CCc2c(c(C(=O)N3CCCC3)nn2C)C1 +COc1cc(=O)c(C(=O)N2CCCCC2)nn1-c1ccc(C)cc1 +Cc1cc(CNC(=O)c2ccnc(-n3cnnc3)c2)n(C)n1 +CC(C)CCc1noc(Cn2cnc3c(oc4ccccc43)c2=O)n1 +CCc1ccc(C2COCCN2S(=O)(=O)c2cccc(F)c2)o1 +NC(=O)C1CCN(C(=O)COc2cccc(Oc3ccccn3)c2)C1 +Cn1c(SCC(=O)OC(C)(C)C)nc2sccc2c1=O +O=C(Cc1noc(C=Cc2cccc3cccnc23)n1)NC1CCCC1 +Cc1nc(NC(=O)C2CCC(=O)N2)sc1Cc1ccccc1Cl +Cc1cc(O)c2c(c1)C(c1c(C)ncnc1C)NCC2 +COC(=O)CNC(=O)COc1ccc2c(c1)OCO2 +CCCNC(=O)c1cnc(N(C)C)nc1COC +Cc1ccc(C(=O)OC(C(=O)N2CCOCC2)c2ccccc2)s1 +CC(C)(C)CCC(=O)Nc1ccc(OCC(N)=O)cc1 +O=C(c1ccccc1)C1CCN(C(=O)C2CCCC2)CC1 +COc1cccc(C(=O)NCC2CCCO2)c1OC(F)F +CN(Cc1ccc(F)cc1)C(=O)c1cnns1 +Cc1nn(C)c(C)c1CNc1cccc2cccnc12 +Cn1cc(NC(=O)c2ccc(Cl)c(Cl)c2)cn1 +Cc1ccc(C2CC(c3cccs3)=Nc3ncnn32)cc1 +Cn1nc(C(=O)NCc2ccccn2)cc1NC(=O)Cc1ccccc1 +CCOC(=O)Nc1cccc(OCc2ccon2)c1 +Cc1cc(CSc2nc3c(cc2C#N)CCCC3)no1 +Clc1ccccc1-c1nn(-c2ncccn2)c2c1CNCC2 +CC(C)c1noc(CCCNC(=O)N2CCc3ccccc32)n1 +COc1cccc(CNc2c(C)c(C)nc3nncn23)c1 +CCCCOc1ccc(CNC(C)=O)cc1OC +CCCOC(=O)CC1c2ccccc2CCN1C(C)=O +COc1cc(C)c(C(=O)NC(C)(C)C(=O)N(C)C)cc1OC +Cc1n[nH]cc1CN1CCCC(c2nc(-c3ccc(F)cc3)no2)C1 +CNc1ncc(CN(C)C(=O)c2cc(C)c(C)[nH]c2=O)cn1 +O=C(NC1CCN(c2ccccc2)C1=O)c1cccc(Cl)c1 +CCOc1ncccc1CNC(=O)C1Cc2ccccc2C(=O)O1 +CC1CN(S(C)(=O)=O)CC1c1nc(-c2ccncc2)no1 +Cc1nccn1-c1ccc(NC(=O)CCC(=O)c2cccs2)cn1 +COc1cc(C)cc(CNC(=O)c2cnc(C3CCCO3)s2)c1 +Cc1ccc(Cc2n[nH]c(CC(=O)Nc3ccc(F)c(F)c3)n2)cc1 +CCOc1ccc(Cl)cc1S(=O)(=O)Nc1ccccn1 +CCCNC(=O)c1sc2nc[nH]c(=O)c2c1C +CCOC(=O)c1cccc(Nc2ncnc(-n3ccnc3)c2N)c1 +O=C(COc1ccc(-n2cnnn2)cc1)NC1CCCc2ccccc21 +COc1ncccc1C(=O)Nc1nc2c(s1)CCCC2 +COCC(C)NC(=O)c1cn(Cc2ccccc2Cl)nn1 +CCc1ccc(C(=O)N(C)c2ccc(O)cc2)s1 +Clc1ccc(Cn2ncc3c(N4CCOCC4)ncnc32)cc1 +Cc1noc(C)c1CC(=O)NC(c1ccc(F)cc1)C(C)C +CC(NC(N)=O)C(=O)Nc1ccc(F)c(Cl)c1 +CCc1cn[nH]c1C1CCN(C(=O)c2cc3sccc3[nH]2)CC1 +CCn1nccc1C(=O)Nc1c2c(nn1C)CCC2 +Cc1cc2nccc(C3CCCN(C(=O)OC(C)(C)C)C3)n2n1 +Nn1c(SCc2ccc(Br)cc2)nncc1=O +Nc1ccccc1CC(=O)Nc1cccc(Cl)c1 +Cn1cc(CCO)c2cc(-c3ccccc3)ccc21 +CC(C)(C)C(=O)NCCN1CCN(c2ccccc2F)CC1 +COc1ccc(NC(=O)Oc2ccccc2F)c(OC)c1 +CCC(NC(=O)Cc1ccc[nH]1)c1cccc(Cl)c1 +COc1ccccc1N1CCN(C(=O)c2cc(F)ccc2C)CC1 +CC(C)C(=O)NCCN(C)C(=O)c1ccc(Cl)cc1O +O=C(CCNC(=O)c1ccco1)NCCc1nnc2ccccn12 +COc1cc(CN2CCOCC2CC(C)C)cc2c1OCCO2 +CC1(O)CCN(C(=O)c2ccc(-n3ccnc3)cc2)CC1O +COc1ccc(-c2nnc(C3CCCC3)n2C)cc1 +COc1ccc(C(=O)N2CCN(c3nc(C)ccc3C#N)CC2)cc1 +CC(=O)Nc1nc(CSc2cc(F)ccc2F)cs1 +Cc1cc(C)c2c(c1)cc(C)c1nn(Cc3ccncc3)c(=O)n12 +COc1ccccc1NC(=O)c1ccc(=O)n(Cc2ccccc2C)c1 +CCOc1cc2c(cc1CNC(=O)c1ccc(OC)cc1)OC(C)C2 +CC1(C(=O)NCc2cc3n(n2)CCCN(C(=O)C2CCC2)C3)CC1 +Cc1ccccc1NC(=O)Cn1c(=O)c2ccccc2n2nncc12 +CC(C)N(C)C(=O)NC1CC(=O)N(C)C1c1ccc(Cl)cc1 +CCc1cccc(OCC(=O)Nc2ccc(NC(C)=O)cc2)c1 +CC(C)N(Cc1ccccc1)C(=O)c1cc2ccccc2oc1=O +CC(C)c1cncnc1N1CCC(C)(O)C(O)C1 +Cn1cc(C(=O)N2CCOCC2)cc(NC(=O)C2CCCC2)c1=O +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccc(C(N)=O)nc1 +Cc1nnc(NC(=O)c2csc(NC3CC3)n2)s1 +O=C(OCCc1ccsc1)c1ccnc(-n2ccnc2)c1 +CC(C)CNC(=O)CSc1ccc(C(=O)C(C)C)cc1 +COc1ccc(NC(=O)N(C)C(C)CC#N)cc1N1CCCC1=O +COCC(C)C(=O)N1CCN(CC(O)C(C)(C)C)CC1 +COC(=O)c1cc(=O)[nH]c2c1c(=O)n(C)c(=O)n2C +CCOC(=O)C(C)(NC(=O)Cc1cccc(F)c1F)C(C)C +CCNc1ccc(S(=O)(=O)C(F)(F)F)cc1NC(=O)CC#N +CC(NC(=O)c1n[nH]c2c1COCC2)C1=CCCCC1 +CCN(CC)C(=O)Nc1cccc(OC(F)(F)F)c1 +CC1CCC(N(CC2CCCO2)S(=O)(=O)c2ccccn2)CC1 +Cc1nn(C)c(C)c1CCC(=O)Nc1nnc(C2CC2)s1 +CCC(CC)c1nnc(NC(=O)C(C)NC(=O)c2ccccc2)s1 +CCn1nc(-c2cc(C(C)C)ccc2OC)cc(CO)c1=O +CCc1ccc(C(C)NC(=O)C(NC(C)=O)C(C)C)cc1 +CCOC(=O)c1nn(-c2cccc(C(F)(F)F)c2)c(N)c1C +CC1=NC2(CCC3CN(C(=O)NC4CCCC4)CC32)C(=O)N1C +O=C(NCC(F)F)C1COc2ccc(F)cc2C1 +Cc1c(C(=O)N2CCC(N3CCNC3=O)CC2)sc2ccccc12 +COc1ccc(Cl)cc1NCc1ccc(C(N)=O)cc1 +Cc1ccc(-n2nc(C)c(C(=O)N3CCOC(C)C3)n2)c(C)c1 +CC(C)c1ccc(-c2ccc(C(=O)N3CCCC3)c(N)n2)cc1 +CC(C)(C)c1noc(CCC(=O)Nc2ccc3cn[nH]c3c2)n1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1cnc(C2CCCO2)s1 +CCC(C)NC(=O)c1cnn2c(C)c(Cc3ccccc3)c(C)nc12 +CC1COCCN1Cc1cn2ccccc2c1C#N +CCOC(=O)Cn1c(C)nc2c(C(=O)OCC)sc(C)c2c1=O +Cc1ccc(CNC(=O)N2CCC(C(=O)N(C)C)CC2)s1 +COCc1nnc(NC(=O)Cc2c(F)cccc2Cl)s1 +Cc1nc(C2CC2)sc1-c1csc(NC(C)C)n1 +Cc1cccc(-c2ncnc(N3CCCCC3)c2N)c1 +Cc1cccc(NC(=O)N2CCN(CC(=O)NC(C)C)CC2)c1 +O=C(Cn1nc(-c2ccco2)oc1=O)NCc1cc(F)cc(F)c1 +Cc1ccc2c(c1)N(CC(C)C)C=NS2(=O)=O +Fc1cccc(F)c1NCc1cnn2ccccc12 +NC(=O)c1cc(Cl)ccc1OCc1ccc(-n2cccn2)cc1 +C#CCN1CCN(C(=O)NC2C3CCOC3C2(C)C)CC1 +COC(=O)C(C)C1Sc2ccccc2NC1=O +Cc1ccc(=O)n(C(C)C(=O)N2CCc3ccccc32)n1 +CC(O)c1cn(CC(=O)NCCCc2cccc(F)c2)nn1 +Cc1csc(NC(=O)NC(C)c2ccccc2)n1 +CC(NC(=O)CCc1ccncc1)c1cccc(N2CCCC2)c1 +Cc1ccc(Cn2nc(C)c(C(=O)N3CCC3)c2C)cc1 +CCCCSc1nnc(Cn2c(=O)sc3ccccc32)n1C +N#Cc1ccc(NC(=O)c2ccnc(-n3cncn3)c2)cc1Cl +COc1cccc(-c2c(-c3ccco3)n[nH]c2N)c1 +Cc1ccc(C(=O)N2CC(S(=O)(=O)c3ccc(F)cc3)C2)cc1 +CCOc1ccccc1NC(=O)c1nc2ncccn2n1 +O=C(NCCCn1cccn1)N1CCCC1c1cccs1 +CCCNc1ncnc2onc(-c3ccc(C)cc3)c12 +N#Cc1ccc(NC(=O)c2ccc(Br)cc2F)cc1 +COC(=O)CN(c1ccc(C)cc1)S(=O)(=O)c1ccccc1 +Nc1cc(S(=O)(=O)N2CCOCC2)ccc1O +Cn1ccc(C(=O)N2CCCCCC2C=Cc2ccccc2)cc1=O +O=C(CNC(=O)C1CCCC1)NCc1ccnc(-n2ccnc2)c1 +CC(Nc1cc2ccccc2c(=O)[nH]1)C1CCCO1 +Cc1ccc(OC2CCN(S(=O)(=O)c3cccnc3)CC2)nn1 +COC(=O)NCC(=O)NC1CCCc2[nH]c(=O)ccc21 +COC(=O)C(Cc1ccccc1)NC(=O)CC1CCCC1 +COc1cccc(N2CCOC(C(=O)N=c3[nH]cc[nH]3)C2)c1 +CC(CC#N)N(C)C(=O)c1ccc2c(c1)OCCO2 +Clc1ccc2nc(CSc3nncn3-c3ccccc3)cn2c1 +O=C(OCC1CC1(Cl)Cl)c1cn(Cc2ccccc2)nn1 +O=C(Nc1ccccc1F)c1n[nH]c2c1CCc1ccccc1-2 +O=C(CSc1ncnn1-c1ccccc1)Nc1nccs1 +Cc1ccc(-c2nc(CN3CCc4cncnc4C3)co2)c(C)c1 +Cc1nc(-c2ccc(NC(=O)c3cnccn3)cc2)cs1 +CCn1cc(NC(c2cccs2)C2CC2)ccc1=O +NC(=O)c1ccc(NC(=O)CCc2nc(-c3cccs3)no2)cc1 +Cc1sc2ncnc(N3CCCCC3CC(N)=O)c2c1C +Cc1cc(CSc2nnc(-c3ccoc3C)n2C)on1 +CNC(=O)C1CCCN(c2cc(C)c(C#N)c3nc4ccccc4n23)C1 +O=C(COC(=O)c1cccnc1Sc1ccccc1)c1ccc[nH]1 +Cc1nn(C)c(C)c1CCC(=O)Nc1ccc(C(F)(F)F)cc1 +CCS(=O)(=O)N1CC2CC(C(=O)N3CCOCC3)C(C1)O2 +CC(NC(=O)c1n[nH]c(N)n1)c1cccc(Br)c1 +CC(C)OC(=O)C1CC(=O)N(c2ccc(OC(C)C)cc2)C1 +Cn1cc(C(=O)CSc2n[nH]c(=O)n2CCc2ccccc2)cn1 +CC(=O)NCCCN(C)C(=O)C1CCCN1C(=O)c1cccs1 +Cc1ccc(C(=O)CNC(=O)c2ccc(F)cc2)cc1 +CCc1ccc(-n2ccc3c(cnc4ncnn43)c2=O)cc1 +Nc1cc(F)cc(Br)c1OCCOCC(F)(F)F +CC(C)C(=O)NCCNC(=O)C(C)Sc1ccccc1 +N#Cc1cnn2ccn(CCCc3ccccc3)c12 +N#Cc1cnn(C2CCCOc3ccc(Cl)cc32)c1N +CNC(=O)CNC(=O)Cc1c(Cl)cccc1Cl +CC(C)NC(=O)CNC(=O)Cc1csc(-c2ccccn2)n1 +COc1cc(C(=O)NC(C)c2cccs2)ccc1OC(F)F +CC(C)NC(=O)CCOc1ccc(Br)cc1 +CC(c1cnn(C)c1)n1ccnc1-c1cccc(O)c1 +CN(Cc1ccccc1Br)C(=O)c1ccc(N(C)C)cc1 +O=C1CCN(C(=O)c2occc2-c2ccccc2)CCN1 +Cn1cc(C(=O)NCc2cccc3cccnc23)cn1 +O=C(COc1ccccc1F)OCc1cc(-c2ccco2)on1 +CCNc1ncnc2c1cnn2-c1cc(Cl)ccc1C +CCSc1ccc(NC(=O)C(C)NS(C)(=O)=O)cn1 +COC(=O)c1ccc(CSc2nc(=O)n3ccc(C)cc3n2)o1 +C=CCOc1ccc(CN(C)c2ccc(C#N)cn2)cc1 +O=C(c1cccc(Cl)c1Cl)N1CCN(C(=O)C2CC2)CC1 +CCOC(=O)Cn1nc(C)c(NC(=O)c2c(F)cccc2F)c1C +CC1CCC(C(N)=O)CN1C(=O)c1cc2c(s1)CCCCC2 +CCCc1cc(=O)n(CC(=O)Nc2nc(C)cs2)cn1 +Cc1ccc(F)cc1NC(=O)C(C)NC(=O)c1ccc(Cl)cc1 +CCN(C(=O)CNc1ccc(C(N)=O)cc1)c1cccc2ccccc12 +Nc1nc(-c2ccccc2)cc(N2CCCCC2)n1 +CN(C)c1ccc(NC(=O)c2ccc(=O)[nH]c2)nc1 +CC(C)CCCCNC(=O)Cn1cnc2c(oc3ccccc32)c1=O +CCC(CNC(=O)c1cnn(-c2ccncc2)c1C)c1ccccc1 +Cc1ccccc1Cn1cc(C(=O)N(C)CC(O)CO)nn1 +Cn1cnnc1SCC(=O)c1ccc2c(c1)-c1ccccc1C2 +CC(C(=O)N(C)CC(=O)N1CCCC1)n1cnc2ccccc21 +O=C(Nc1cnn(CCc2ccccc2)c1)c1ccccn1 +O=C(Nc1nc(C2CC2)cs1)c1occc1COc1ccccc1 +Cc1n[nH]c(-c2ccc(C(=O)NC(C#N)C(C)(C)C)cc2)n1 +Cc1nc(Cc2nc(CC(=O)NC3CCCCC3)no2)cs1 +Cc1c(-c2nn3c(-c4ccncc4)nnc3s2)cnn1C +CN1C(=O)Cc2cc(C(=O)NCc3ccccn3)ccc21 +O=C(Nc1nccs1)c1cc(-c2ccc(Br)cc2)[nH]n1 +CCN1C(=O)Cc2cc(NC(=O)c3ccc(OC)cc3OC)ccc21 +O=C(Nc1ccc2[nH]c(C(F)F)nc2c1)c1ccc2[nH]cnc2c1 +COc1cc(C(=O)Nc2nnc(C3CC3)s2)cc(OC)c1C +CCCC(=O)N1CCCCC1C(=O)Nc1cccnc1 +O=C1CCN(C(=O)c2ncn(-c3ccccc3)n2)c2ccccc2N1 +CCC(CC)N(CCO)c1cc(C)cc2ncnn12 +Cc1nc(SCC(N)=O)c2c(=O)n(C)c(=O)n(C)c2n1 +COc1ccc(OCCNC(=O)c2cc(F)cc(F)c2)cc1 +CN(C)c1cncnc1-n1cc(NC(=O)Cc2cccc(F)c2)cn1 +O=C(Nc1cccc(N2CCCC2)c1)C1COCCO1 +COC(=O)CC(c1ccc(OC)c(OC)c1)C(C)C +CCCC(NC(N)=O)C(=O)N(C)c1cc(C)ccc1C +CC(=O)NC(C(=O)Nc1ccc(Br)cc1F)C(C)C +NC(=O)c1cc2ccc(OC(=O)c3ccccc3Cl)cc2oc1=O +CN(CC(=O)NC1CC1)C(=O)CCc1nc(C(C)(C)C)no1 +COC(=O)Cc1cccc(NC(=O)c2ccco2)c1 +CCOC(=O)c1nnnn1C(C)c1ncc(C(F)(F)F)cc1Cl +Cc1cc(Br)ccc1C(=O)N(C)CC(C)C#N +CC(c1ccccc1F)N(C)C(=O)c1ccccn1 +CC(C)n1nc(CNC(=O)c2cccs2)c2ccccc21 +COc1ccc(NC(=O)C(C)n2nc(C)ccc2=O)cc1 +CC(C)c1ncc(CN2CCN(c3cnn(C)c3)C(=O)C2)s1 +Cc1cc(C)c2c(N(C)CCc3c(C)n[nH]c3C)ncnc2n1 +CC(C)(C)OC(=O)N1CCCC(CS(=O)(=O)c2cnccn2)C1 +COc1ccc(CNc2ccc(C#N)cc2N)c(OC)c1 +O=C(CSc1nc(C2CC2)n[nH]1)c1ccc(F)c(F)c1 +O=C(NCCCc1cccc(F)c1)C1CCN(c2ncccn2)CC1 +N#Cc1ccc(F)c(CN2C(=O)Cc3ccccc32)c1 +CCc1oc2ccccc2c1CN(C)C(=O)c1cccnc1 +CC1(NC(=O)NCc2cn(-c3ccccc3)nn2)Cc2ccccc2C1 +COc1nc(OC)nc(N2Cc3cnn(CCO)c3C2)n1 +Cc1cnc(NC(=O)Cc2ccc(C)c(C)c2)s1 +Cc1cccc(CCNC(=O)CN(C)S(=O)(=O)c2ccccc2)c1 +C#CCNC(=O)c1cc2c(s1)-c1ccccc1CC2 +COCCC(=O)c1cc2c(cc1Cl)OCCO2 +Cc1nn(C)c(C)c1CCN(C)C(=O)Nc1cccc(F)c1 +CCc1cc(NC(=O)c2csc(-c3cnn(C)c3)n2)[nH]n1 +CCC(=O)Nc1nc2ccc(CC(=O)N3CCCCC3)cc2s1 +CC(NC(=O)CC12CC3CC(CC(C3)C1)C2)C1CCCO1 +O=C(NC1CC1)c1cccn1-c1nnc(N2CCCCC2)s1 +COc1ccc(Cl)c(C(=O)N2CCOC3C(OC)CCC32)c1 +CC(NC(=O)OC(C)(C)C)c1noc(-c2cnccn2)n1 +Cc1cc(C(=O)NC(Cc2ccccc2)C2CC2)c2c(C)nn(C)c2n1 +CC(O)(CNC(=O)Cn1ccnn1)c1ccc(F)cc1 +C=CCn1c(C)cc(C(=O)Cn2cnc3ccccc32)c1C +O=C(Nc1ccc2nccnc2c1)N1CCCCC1 +CCCCNC(=O)C1CCN(c2ccc(Cl)cc2)C1=O +CCCCOc1cccc(NC(=O)c2ccc3c(c2)OCC(=O)N3)c1 +O=C1CC(N2CCCCCC2=O)c2cc(F)ccc21 +O=C(c1csc(COc2ccccc2F)n1)N1CCOCC1 +O=C(c1ccc(Cl)cc1)C1CCN(C(=O)C2CC2)CC1 +CNC(=O)CN(C)S(=O)(=O)c1cc(OC)c(OC)cc1C +Cc1ccc(CN2CC(C(=O)NCCC3=CCCCC3)CC2=O)cc1 +CCC(=O)N1CCC(C(=O)NCC(C)Cc2ccc(OC)cc2)C1 +CNC(=O)c1cc(OC)ccc1NC(=O)c1ccccc1Cl +CC12CC(NC(=O)N1c1ccc(F)cc1F)c1ccccc1O2 +COCC(NC(=O)Cn1ncc2ccccc21)C(N)=O +COc1cccc(C(=O)N2CCN(Cc3ccncc3)CC2)c1O +CCCn1nccc1NC(=O)OCC(F)(F)F +Cc1noc(C2CCCN(c3nccc4occc34)C2)n1 +C=CCNC(=O)Nc1nnc(Cc2cccc(OC)c2)s1 +c1csc(C2CCCN(Cc3cnc(C4CC4)s3)C2)n1 +C#CCn1c(C(C)NC(=O)CC)nc2ccccc21 +CN(C)C(=O)c1nn(C)c2c1CCN(Cc1ccc3c(c1)OCO3)C2 +Cc1cc(NC(=O)c2ccc(-c3ccc(F)cc3)o2)no1 +CN(c1ccc2c(c1)OCO2)S(=O)(=O)c1ccc(N)cc1 +Cc1ccc(S(=O)(=O)N(C)CCC(C)C)s1 +O=C(c1cccnc1)N1CCN(c2ccc(-n3cccc3)nn2)CC1 +Cc1noc(C(C)C)c1C(=O)N1CCN(c2ccc(Cl)cn2)CC1 +CN(C)c1ccc(-c2cc(C#N)nn2CCO)cc1 +O=C(N1CCC2(C1)OCCO2)C1(c2ccc(F)cc2F)CCCC1 +Cc1noc(NC(=O)Nc2ccccc2)c1Cl +Cc1nc2ncnn2c(C)c1CCC(=O)N(C)CCC(F)(F)F +Cc1cc(CNC(=O)N2CCC(c3nc4ccccc4o3)CC2)no1 +Nc1oc(C(F)(F)F)cc1C(=O)C1CCCCC1 +Cc1ccc(NC(=O)CCCc2cccs2)cc1-n1cnnn1 +CCS(=O)(=O)N1CCC2(CC1)CC(OCC1CC1)CO2 +C#CCNC(=O)NCC1(CN2CCOCC2)CCCCC1 +COc1ccc2oc(=O)c(C(=O)NCc3ccccc3)cc2c1 +CCOC(=O)C(CC)n1c(-c2ccccn2)ccc(C#N)c1=O +Cn1cnc(CNS(=O)(=O)c2cccc(C(F)(F)F)c2)n1 +COc1ccccc1-c1nnc(CS(=O)(=O)c2ccccc2)o1 +COc1ccc(C(C#N)N(C)C(=O)C2CCCO2)cc1 +Cc1noc(CCC(=O)Nc2ccc(OC(F)F)cc2)n1 +COc1cc(Cl)c(CNC(=O)CCc2ccccc2)cc1OC +CCOC(=O)C1CNC(=O)C12CN(C(=O)OC(C)(C)C)C2 +Cc1nnc(-c2cnn(C)c2N)n1Cc1ccccc1F +COc1ccc(CC(C)CNC(=O)Cn2ccc(=O)n(C)c2=O)cc1 +CC(=O)Nc1ccc(SCC(=O)Nc2cccc(C)c2)nn1 +CCC(C)c1cc(C(=O)Nc2cc(F)ccc2OC)on1 +CC(=O)Nc1ccc(NC(=O)c2ccccc2OC(F)F)cc1 +Cc1cnn(CC2CCCCN2C(=O)C2CC(=O)N(C3CC3)C2)c1 +N#Cc1ccnc(N2CCC3(CCC(=O)N(CCCO)C3)CC2)c1 +Cc1ccc(NC(=O)COc2ccc(F)cc2)c(O)c1 +CC(CC(=O)Nc1sccc1C(=O)NC1CC1)c1ccc(F)cc1 +CN(c1ncnc2sccc12)C1CCc2ccccc21 +CCNC(=O)CN(CC)C(=O)c1ccc(N(C)C)cc1 +O=c1c2sccc2ncn1Cc1cccc(OC(F)F)c1 +Cc1cc(NCCCn2cnnc2)n2nc(C)c(C)c2n1 +COc1ccc(C)cc1-c1ccc(C#N)c(=O)n1C1CC1 +O=C(NCCc1nc2c(s1)CCCC2)Nc1ccc2c(c1)COC2 +c1ccc(CC2CCN(c3ncccn3)CC2)nc1 +CC(C)Cc1nnc(NC(=O)c2cc(N)ccn2)s1 +CC(C)C(C(=O)Nc1ccccc1N)n1ccc(=O)cc1 +CC(C)Oc1ccc(C(=O)NCC(=O)Nc2ccc(F)c(F)c2)cc1 +Cc1cccc(S(=O)(=O)NCc2sccc2C)c1 +O=C(Nc1cnccn1)C1CC2OCCC2N(Cc2ccsc2)C1 +Cc1ccc(Cl)cc1NC(=O)CCn1cnc2c(cnn2C)c1=O +CCn1cc(NC(=O)c2ccc(Cl)cc2N)cn1 +CCc1ccccc1NC(=O)NC1CCN(C(=O)OC)CC1 +O=C(NCC(O)(c1ccccc1)C1CC1)C1COc2ccccc2O1 +Cc1ccnc(Nc2nc(CC(=O)Nc3cccnc3)cs2)c1 +CCCCOC(=O)C(C)n1c(N)nc2cc(F)c(F)cc21 +COc1c(C2CCCN2C(=O)CCc2ccco2)c(C)nn1C +CCC(=O)N1CCC(c2nc(-c3cccc(OC)c3)no2)CC1 +Cc1nnnn1C(C(=O)N1CCn2cncc2C1)c1ccccc1 +O=C(NCc1ccccc1F)c1cccc(Cl)c1 +C#CCOc1ccc(CN2CCOC(C(=O)OC)C2)cc1 +Cc1cc(Cl)ccc1NCC(=O)Nc1c(C)nn(C)c1C +Brc1ccn2nc(-c3cccs3)ncc12 +O=C1COc2cc(C(=O)OCc3cccc4cccnc34)ccc2N1 +O=C(NC1CC(=O)N(C2CC2)C1)c1cc2n(n1)CCCO2 +Cc1ccc(OC(=O)Cn2ccc(=O)n(C)c2=O)c(Cl)c1 +CCCCN(CC#Cc1ccccc1)C(=O)CNC(=O)N(C)C +CCCSc1ccc(N)c(NC(=O)c2ccsc2)c1 +O=C(NCc1ccc(CO)cc1)c1cc(C(F)(F)F)n[nH]1 +Cc1ccc(S(=O)(=O)Nc2c(C)cccc2N)cc1 +O=C(NCc1ccc2c(c1)OCO2)c1nc[nH]c1-c1cccnc1 +O=C(Nc1ccccc1Cl)c1ccc(N2CCOC2=O)cc1 +Cc1nn(CC(=O)NCCCN2CCCC2=O)c(=O)c2cccn12 +COCCCNc1cc(C(C)C)nc2nc(-c3cccnc3)nn12 +O=C1CCC2(C(=O)Nc3nccs3)Sc3ccccc3N12 +CN(CC(N)=O)C(=O)c1csc(-c2ncccn2)n1 +Cc1c(-c2noc(-c3ccccc3F)n2)nnn1Cc1ccccc1 +COC(=O)CC(c1cc(C(C)(C)C)ccc1C)C(C)C +CC(C)n1nc(C(=O)OCc2ccccn2)c2ccccc2c1=O +O=C1CC(C(=O)N2CCCC2Cn2cccn2)CN1CC1CC1 +COC1CC(OCc2ccccc2)C2COC1(CCCO)O2 +CC(C)CC(NC(=O)c1cccnc1)c1cccs1 +Cc1cc(S(=O)(=O)NC(C)(C)CO)cc(N)c1C +N#CC(C(=O)CCn1ccccc1=O)c1nc2ccccc2[nH]1 +Cc1ccc(C2(O)CCN(c3cc(C)ncn3)C2)cc1 +NC(=O)c1ccccc1-c1ccc2nc(CO)[nH]c2c1 +COC(=O)C(NCC(F)(F)F)c1cccc(OC)c1 +Cc1cc(NC(=O)COc2ccc(Br)cc2Cl)no1 +Cc1ccc(C)c(NC(=O)c2cnc(-c3ccco3)nc2N)c1 +CCOc1ncccc1CNC(=O)c1cc(Br)c[nH]1 +COc1cc(NC(=O)c2cn(C)nn2)cc(OC)c1OC +Cc1cccc(OCC(=O)Nc2ccccc2C(=O)N(C)C)c1 +CCS(=O)(=O)N1CCC(C(=O)Oc2ccc(Cl)cc2C)CC1 +COc1ncc(C)cc1NC(=O)NC(C(N)=O)C(C)(C)C +CC(C)=CCN1C(=O)C2CCC1CN(C(=O)CCc1ccsc1)C2 +CC1CCN(C(=O)NCC(=O)N2CCc3sccc3C2)CC1 +CCCn1cc(Cl)c(C(=O)N2CCC(c3cncc(C)n3)CC2)n1 +Cc1ccc(NC(=O)CCNC(=O)CC2CCCCC2)nc1 +Cc1n[nH]c(NCCCN2CCOCC2)nc1=O +Fc1ccc(C2(c3nc(C4CCOC4)no3)CCOCC2)c(F)c1 +O=C(Nc1ccccc1C(=O)N1CCCCCC1)C1CCCC1 +CNC(=O)c1cccc(OS(=O)(=O)c2ccc(C)s2)c1 +COc1ccc(CC(=O)NCCc2nc3ccccc3[nH]2)cc1OC +Cc1n[nH]cc1NC(=O)COc1ccc(F)c(Cl)c1 +CC(C)NC(=O)c1cc(C2CC2)nn1-c1ccccc1 +CCc1c(C)nn2c(=O)cc(CC(C)n3cccn3)[nH]c12 +CC(C)CCC(=O)OCc1nnc(-c2ccccc2)o1 +Cc1ccc(CN2CC(=O)N3Cc4ccccc4CC3C2=O)cc1 +CCc1cc(C(=O)Nc2ccc(Cl)cn2)cs1 +CCN(CC)c1ccc(C(=O)NC(C)C(C)(C)C)cn1 +CN(C)c1cc(=O)n(C)c(=O)n1-c1ccc(F)cc1 +Cc1ccc(C)n1CCOc1ccc2ncccc2c1 +O=C(CCc1ccsc1)N(Cc1ccccc1)c1ccccn1 +Brc1ccnc2ccn(-c3cc[nH]n3)c12 +Cc1nsc(N2CCN(Cc3ccc(C)c(C)c3)CC2)n1 +Cc1ccc2nc(C)c(C(N)c3ccncc3)n2c1 +Cc1ccc2cccc(C(=O)N(C(C)C)C3CCOCC3)c2n1 +CN(C)C(=O)CN(C)C(=O)CCc1ccc(-c2ccccc2F)o1 +CCCOc1ncccc1CNC(=O)Cc1ccccc1O +CN(Cc1ccccc1)C(=O)C1CCN(c2ccc(Cl)cc2)C1=O +COc1cccc(COC(C)C(=O)NCc2c(C)cc(C)[nH]c2=O)c1 +COc1cc(-n2cnnn2)c(Cl)cc1C(=O)OCc1ccoc1C +Cc1ccc(C(C)C)c(OC(C)C(=O)NCCO)c1 +Cc1cc(F)ccc1CCNC(=O)CCc1c(C)nn(C)c1C +CCc1ccc2c(CC(=O)NCc3nnc4ccccn34)coc2c1 +COc1ccc(NC(=O)Cn2c(C)cc(C)c(C(N)=O)c2=O)cc1 +Cc1occc1CNC(=O)NCc1cccc(-n2cccn2)c1 +CC(C)c1nnnn1-c1ccc(N)c(C(F)(F)F)c1 +COc1ccc(-c2ccc(C(N)=O)c(N)n2)cc1F +Cc1cc(NC(=O)CNC(=O)c2ccco2)ccc1Br +O=C(CCCn1cncn1)Nc1ccccc1-n1ccnn1 +CC(=O)Oc1ccccc1C(=O)NCc1ccccn1 +CCNC(=O)c1ccc(NC(=O)C2(C#N)CCCC2)c(C)c1 +CN(CC1CC1)C(=O)Nc1cccc(-n2cccn2)c1 +CCOC(=O)N1CCN(CCCc2cn[nH]c2)CC1 +CNC(=O)c1cccc(NC(=O)c2ccc(Cl)c(OC)c2)n1 +CCC(CCO)NC(=O)Nc1nnc(Cc2cccc(F)c2)s1 +CCOC(=O)c1cc(C)nc2c1c(C)nn2-c1nc2ccccc2[nH]1 +COc1cc(S(=O)(=O)NCc2ccncc2)c(OC)cc1C +CCOC(=O)C1CCN(C(=O)CCOC(C)C)CC1 +CC(c1ccncc1)N(C)C(=O)c1cc(-c2ccccc2)no1 +CC(=O)N(C)c1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1 +O=C(Cc1ccccc1F)N1CCn2nncc2C1 +CNC(=O)CN1c2ccccc2C(=O)N(C)C1c1ccc(OC)cc1 +COCC(=O)N1CCc2nnc(CCc3ccccc3)n2CC1 +CC1CCN(C(=O)c2ccc3c(c2)CCCC3)CC1 +COc1cc(OC)c(NC(=O)Cc2cccc(F)c2)cc1F +CCN(Cc1ccc2c(c1)OCO2)C(=O)NCCCn1cccn1 +O=C(NCCNC(=O)c1cnc2sccn2c1=O)c1ccccc1 +CN(C)c1ncnc2c1CCN(C(=O)C1CCCC1)CC2 +Cc1ccc(NC(=O)CN(C)C(=O)CCC(=O)c2cccs2)cc1 +O=S(=O)(C1CC1)N1CCC2(C=Cc3ccccc32)CC1 +CC(C)(C(=O)NCCNC(=O)c1cccnc1)c1ccc(F)cc1 +NC(=O)C1CCN(C(=O)OCc2ccccc2)CC1 +CNc1nc(-c2ccc(=O)n(CC(C)C)n2)cs1 +Cc1cc(C)c(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)o1 +COC(=O)C1CCCN(S(=O)(=O)c2ccc(C)s2)C1 +COc1ccc(Cc2nc3cc(F)cc(N)c3o2)cc1OC +CCC(=O)Nc1cnc(-c2ccc(OC)cc2)nc1 +CC(C)(CNC(=O)C1CC(=O)Nc2ccccc21)c1ccncc1 +Oc1ccccc1N1CCN(CC(O)CN2CCOCC2)CC1 +CC(C)=CC1C(C(=O)NCCNc2cnccn2)C1(C)C +OCCOCCSc1ccc2c(c1)OCCCO2 +N#Cc1cccc(NCC(O)c2cc(F)ccc2F)c1 +Cc1ccc2cc(CN(C(=O)c3ccccc3)C(C)(C)C)c(=O)[nH]c2c1 +Cc1ccc(CC(=O)NCCNC(=O)c2ccc(O)cc2)cc1 +CN(Cc1ccco1)C(=O)NCc1cccc(OCC(F)F)c1 +CN(C(=O)c1c(-c2ccccc2)cnnc1N)C1CCCCC1 +Cc1ccc(-n2cnnc2SCCCc2cnn(C)c2)c(C)c1 +CC1CN(Cc2ccccc2CNC(=O)Cn2cnnn2)CC(C)O1 +CCOC1CC(N(C)C(=O)C2CCC2)C12CCCCC2 +CC(C)N(C)C(=O)C1CCN(Cc2cnc(C(C)(C)C)s2)CC1 +COC(=O)c1cn(-c2ccc(C(C)=O)cc2)c(C)c1C(=O)OC +O=C1C2Cc3ccccc3CN2CN1C1CCCCC1 +CC1(C)CC1C1NCCc2ccc(O)c(Cl)c21 +COC(=O)C(NS(=O)(=O)c1cccc(F)c1)C(C)C +COC(=O)C1CCN(C(=O)c2oc3ccccc3c2C)CC1 +COc1cc2nc(C3CCC3)nc(N3CCCC3CO)c2cc1OC +O=C(NCC1CCN(c2ccccc2)C1)Nc1ccc2[nH]ncc2c1 +Cc1ccsc1C(=O)N1CCN(c2cc(C#N)ccn2)CC1 +CCN1CC(C(=O)Nc2ccccc2Sc2ccccc2)CC1=O +Cc1cn2c(CCC(=O)N3CCC4(CC3)OCC(C)O4)csc2n1 +Cn1ccc(NC(=O)C2CCN(C(=O)c3cccs3)CC2)n1 +Cc1ccc(C)c(OC2CCN(S(=O)(=O)N(C)C(C)C)CC2)c1 +Cc1cc(=O)c(C#N)nn1-c1ccc(Br)cc1 +COc1cc(C(=O)N2CCCC2c2ccncc2)ccc1OC(C)C +O=S(=O)(C1CC1)N1CCC(c2ccc3c(c2)OCO3)C(O)C1 +Cn1cnnc1S(=O)(=O)Cc1cccc(Cl)c1 +CC(C#N)(c1ccc2c(c1)OCO2)N1CCOCC1 +COC(=O)c1cccc(S(=O)(=O)NCc2scnc2C)c1C +O=C(NCC(O)c1ccc2ccccc2c1)c1ccc(Cl)cn1 +CC1(NC(=O)CNC(=O)OCC(F)(F)F)Cc2ccccc2C1 +CC(C(=O)N1CCOCC1)N1CCN(Cc2cc(C#N)cs2)CC1 +Cc1nc2ccccc2n(Cc2cn3ccccc3n2)c1=O +CCC(NC(=O)NCc1ccc(C#N)cc1)C(C)C +COC(=O)c1cc(F)c(N2CCOCC2)c(F)c1F +N#Cc1cc(NC(=O)NCCNC(=O)CC2CCCCC2)ccc1F +CCNC(=O)C(C)NC(=O)c1ccccc1Cl +COCC(C)NC(=O)Nc1cc(-c2ccccc2)nn1C(C)C +CCS(=O)(=O)N1CCN(c2nnnn2-c2ccccc2)CC1 +CCCOc1ccc(COC(=O)C2CCN(C(=O)N(C)C)CC2)cc1 +Cc1ccc(NC(=O)Cc2ccccc2Cl)cc1N +CC(NC(=O)c1ccc(-n2ccnn2)cc1)C(=O)NCc1ccco1 +Cc1nc(-n2c(C)ccc2C)sc1C(=O)N1CCCC1 +Cc1ccsc1C(=O)Nc1cc(F)ccc1F +Cc1ccccc1C(C)NC(=O)CCn1ccccc1=O +COc1ccc(OC)c(CNC(=O)c2cccnc2N)c1 +Cc1ccc(C(=O)N(C)C)cc1NCCOc1ccc(C#N)cc1 +CC(C)N(C)C(=O)c1ccc(OCC(N)=O)cc1 +CCS(=O)(=O)NC1CC(=O)N(c2cccc(F)c2)C1 +Cc1ccc(CNC(=O)c2cc3ccccc3oc2=O)cc1 +CCCC(C)(C)NS(=O)(=O)c1cc(OC)ccc1OC +CCC(C)n1ncc(C(=O)Nc2ccc(C(N)=O)c(F)c2)c1C1CC1 +Cn1cc(C(=O)N2CCC(Oc3ncccc3Cl)CC2)nn1 +Clc1cccc(CNc2nnc3n2CCCCC3)c1 +O=C(Nc1cccc(Cl)c1)Nc1cccc(CO)c1 +C#CCOc1ccc(CN2CC(C)OC(CC)C2)cc1 +CCOC(=O)N1CCC(OC(=O)c2cnn(-c3ccccc3)c2)CC1 +CN(CCO)C(=O)CCCc1cc(F)ccc1F +COc1cccc(F)c1-c1nc2c(cnn2C(C)C2CC2)[nH]1 +Cc1ccc(CCN(CC2CCCO2)C(=O)c2cnccn2)cc1 +CCOc1cc(-c2cc(-c3c(C)n[nH]c3C)nc(N)c2C#N)ccc1O +CCn1nc(-c2ccc3ccccc3c2)cc(C(C)=O)c1=O +COc1ccc(CNC(=O)C(C)c2ccsc2)c(OC)c1 +CCC(C)NS(=O)(=O)c1cc(Cl)c(OC)cc1Cl +CCC1CN(CCC(N)c2ccc(Cl)cc2)CCO1 +CCNC(=O)N1CCN(C(=O)CCCNC(=O)c2ccco2)CC1 +CC(C)c1ccc(OCCC(=O)N(C)Cc2nnc3n2CCC3)cc1 +NC(=O)c1cccc(COC(=O)c2cccc(Cl)c2Cl)c1 +CCn1c(N2CCC(C(=O)NCCO)CC2)nc2ccccc21 +CC(=O)Nc1nc(C(=O)Nc2cc(C)cc3cccnc23)cs1 +Cc1cc(N2CC34C=CC(O3)C(C(=O)NCCC(C)C)C4C2=O)no1 +COc1cc(C)c(COC(=O)c2cc(C)oc2C)cc1OC +O=C(Nc1ccc(NC(=O)C2CCCO2)cc1)c1ccc(F)nc1 +COc1c(Br)cc(Cl)cc1NC(=O)c1cscn1 +Cc1cc(C)n2c(CNC(=O)Cc3ccc(Cl)cc3)nnc2n1 +CCCC(=O)N(C)CCc1noc(-c2ccc(C)cc2)n1 +O=C(NCC1CC1)NCC1(c2cccc(Cl)c2)CCOCC1 +CCC(NS(=O)(=O)c1cccc2cnccc12)C(C)C +COC(C(=O)N1CCn2c(nnc2C(C)C)C1)c1ccccc1 +Cn1c(=O)n(C)c2cc(N3CCOCC3)c(NS(C)(=O)=O)cc21 +Cc1n[nH]c(C)c1C(=O)N(C)C(C)c1ccncc1 +CN(C)c1ccc(-c2noc(C(=O)NCC3CCCO3)n2)cc1 +CN(Cc1ccncc1)S(=O)(=O)N1CCc2ccccc2C1 +CCc1ccc(-c2c(C)c(-c3cnn(C)c3)nc(N)c2C#N)o1 +CCNc1c(F)cccc1C(=O)N(C)C(C)C(C)C +c1cncc(COC2CN(C3CCOCC3)C3COCC23)c1 +CC(C(=O)N(CCO)C1CCCCC1)n1cncn1 +NS(=O)(=O)c1ccc(Oc2cc(C(F)(F)F)ccn2)cc1 +Cn1c(=NC(=O)CCNc2ncccn2)[nH]c2cc(Cl)ccc21 +O=C1NCCN2CCN(Cc3ccc4cc(Cl)ccc4n3)CC12 +CC(C#N)(NC(=O)CNc1ccccc1Cl)C1CC1 +C#Cc1cccc(NC(=O)c2cccc(S(=O)(=O)N(C)C)c2)c1 +COc1ccccc1C(NC(=O)c1ccc(C#N)cc1)c1noc(C)n1 +CCCSc1nc2nc3c(cn2n1)C(=O)CC(C)(C)C3 +O=C(Nc1cccc2ncccc12)c1nccc2ccccc12 +CCOC(=O)C(C)Nc1ccc(C(F)(F)F)cn1 +c1ccn2cc(CSc3ccc(-c4ccncc4)nn3)nc2c1 +Cc1cc(NC(=O)N(CCc2ccccc2)Cc2ccncc2)no1 +Cn1nc(C(=O)N2CCC(c3c[nH]c4ccccc34)CC2)ccc1=O +CC(C)C(=O)c1cc2c(cc1NC(=O)c1ccccc1F)OCCO2 +CC(C)C(NC(=O)c1ccccc1)C(=O)N(C)C(C)C +NC(=O)NC(CC(=O)NCc1ccccn1)c1ccccc1F +CC(C)(C)n1cc(C(=O)N2CCC(C(O)c3ccccc3)CC2)cn1 +Cc1ccc(C(=O)NCCS(N)(=O)=O)cc1C +CCOC(=O)CN(C(=O)c1nnn(-c2ccc(C)cc2)c1C)C1CC1 +Cc1cnc(C(=O)Nc2c(C)cccc2C(C)C)cn1 +Cc1ccc(NC(=O)N(C)C)c(C(=O)NC2CCCCC2)c1 +CCCC(NC(=O)CSc1nc(N)nc(N)n1)c1ccccc1 +COc1cc2ccccc2cc1C(=O)OCC(=O)NCc1ccco1 +COc1ccc(Cl)cc1NC(=O)N(C)Cc1cc(C)on1 +O=C1CC(c2ccc(F)cc2)c2cc3c(cc2N1)OCO3 +COc1ccccc1CCN(C)Cc1cnc2ccc(C#N)cn12 +Nc1ccc(F)c2c(NCCCCCO)nccc12 +Cc1noc(C)c1NC(=O)Nc1ccccc1N1CCOCC1 +CS(=O)(=O)NCCC(=O)NC(c1ccc(F)cc1)C1CCCO1 +CC(NC(=O)c1cccc(NC(=O)c2cccs2)c1)C1CC1 +Nc1nncn1C(=O)COc1ccc(Cl)cc1Cl +Cc1[nH]c2ccccc2c1C(=O)NCc1cccnc1 +CCOC(=O)c1cnn(-c2nc3ccccc3s2)c1O +Cc1noc(C)c1CSc1ccccc1C(=O)OC(C)C(N)=O +Cn1cc(C(=O)Nc2cccc(C(N)=O)c2)c2ccccc21 +Cc1ccc2cnn(CCCNC(=O)c3ccnn3C)c2c1 +Nc1ccccc1S(=O)(=O)Nc1ccc2c3c(cccc13)CC2 +CC(=O)N1CN(Cc2cccnc2)Cc2c1sc1c2CCCC1 +CCCc1cc(C(=O)NCc2nc3c(s2)CCCC3)[nH]n1 +CC(=O)Nc1ccc(Nc2ccc3nnnn3n2)cc1Cl +O=C(Cc1cccc(F)c1F)NCCC(=O)Nc1ccccc1 +Cc1cc(NC2CCOc3ccccc32)n2ncnc2n1 +COc1ccc(CC(=O)N2CCNc3ccccc3C2)cc1OC +Cn1nc(C(=O)Nc2ccccc2C#N)c2c1-c1ccccc1OC2 +COc1ccc(NC(=O)Nc2ccccc2C(N)=O)cc1OC +CN(C)c1cc(C(=O)N2CC(=O)Nc3ccccc32)c2ccccc2n1 +CC(C)C(C)(C#N)NC(=O)Cn1cc(-c2ccccc2)cn1 +c1cnc(N2CCC3(CC2)CCN(c2ncccn2)C3)nc1 +Cc1csc(N(C)C(=O)C2COc3ccccc3O2)n1 +O=C(COC(=O)Cc1ccc(Cl)cc1)NCc1ccccc1 +Cc1cccc2[nH]c(CCN(C)C(=O)c3cc(C4CC4)n[nH]3)nc12 +CC1c2cccn2CCN1CCS(=O)(=O)c1ccc(Cl)cc1 +O=C(CNC(=O)c1ccccc1)OCc1nc2ccccc2o1 +CN(C)c1ccc(C#CCNC(=O)c2cc3ccccc3oc2=O)cc1 +COC(=O)CCC(=O)NC(C)c1cnc(-c2ccncc2)nc1C +O=C(c1ccc[nH]1)N1CCC(CN2CCOCC2)CC1 +Cc1ccc(C(=O)NCCCc2cccc(Cl)c2)c(=O)[nH]1 +CCC1CN(C(=O)NC2CCN(c3ncccn3)CC2)CCO1 +CCN(Cc1cc(=O)n2oc(C)cc2n1)c1ccccc1 +CCCc1nnc(NC(=O)N(C)C(C)c2ccco2)s1 +C=CCNC(=O)c1ccccc1NCC(=O)NC1CCC(C)CC1 +Cn1ccnc1SCc1ccc(C(=O)N2CCCC2)cc1 +O=C(COC(=O)c1ccc(CO)cc1)Nc1ccc2ccccc2c1 +COc1c(C(=O)NCc2cscn2)sc(C)c1Br +CC(C)CCNC(=O)C1CN(C(=O)c2ccc3c(c2)OCO3)C1 +COc1cccc(OCC(=O)Nc2nnc(C3CCCO3)s2)c1 +Cc1cc(C(=O)NC(C)(C)C(N)=O)nn1C(C)(C)C +N#CC1(C(=O)Nc2ccc(Br)cc2)CCCC1 +Cc1cccc(S(=O)(=O)N2CC(OCc3cccc(F)c3)C2)c1 +Cc1cnn(CCCNc2nc(-c3cccnc3)nc(C)c2C)c1 +O=C(CCNC(=O)c1csnn1)NCc1cccnc1 +Cc1sc2[nH]c(SCC(=O)N(C)C)nc(=O)c2c1C +CCCCc1nc2ccc(NC(=O)C(C)OC)cc2[nH]1 +CCCN(CC1CCCCC1)C(=O)c1ccc(C(=O)N(C)C)cc1 +CCCCc1cc(N)cc(S(N)(=O)=O)c1OC +CN(C(=O)c1[nH]nc(C2CC2)c1Br)C(C1CC1)C1CC1 +CC(=O)c1ccc(Oc2ccc(C(=O)NCc3ncc[nH]3)cc2)cc1 +COCCCNc1cc(C(F)(F)F)ccc1NC(C)=O +COC(=O)Nc1cccc(C(=O)Nc2cc(C#N)cn2C(C)(C)C)c1 +C=CCNc1ncnc(Nc2ccc(Br)cc2F)c1N +COC(=O)CNC(=O)c1ccc(-c2cccs2)[nH]c1=O +Cn1c(=O)c2c(-c3ccncc3)c(C#N)c(N)nc2n(C)c1=O +CNC(=O)NCC(=O)NCCc1ccc(F)cc1F +CCCn1cnnc1CNc1cc(C)nc(-c2ccccc2)n1 +Cc1sc(=O)n(CC(=O)NCC(C)(C)C(N)=O)c1C +CCCn1nccc1C(=O)Nc1ccc(F)cc1C +CN(Cc1ccc(C(N)=O)cc1)C(=O)NCC#Cc1ccccc1 +CCC(=O)NC1CCCN(c2nnc(C(F)(F)F)s2)C1 +COc1ccc(C(C)NC(=O)c2ccoc2C)cc1F +COc1ccccc1CC(=O)N(CC1CCCO1)c1ccncc1 +CCNc1ccc(C(=O)NCCCOC)cc1C +Cn1c(C(=O)NCc2ccncc2)nc2c1CCN(S(C)(=O)=O)C2 +Cc1ccccc1-n1nnnc1SCC(=O)N1CCN(C)CC1 +Cc1nc(N(C)C)nc2c1COCC21CCN(Cc2ccccc2)C1 +O=C(OCCc1cccnc1)c1cccc2cn[nH]c12 +CCc1nc2sc(=Cc3ccc(F)cc3)c(=O)n2n1 +CC(=O)Nc1cc(Br)c(O)c(Br)c1 +CN(C)c1ccc(Br)c(OC2CC2)c1 +Cc1ccc(N2CCC(c3cc4cccnc4[nH]3)CC2)nn1 +CCN(CC)C(=O)c1ccccc1SCCOC +Cc1cc(N2CCN(C(=O)c3ccoc3)CC2)nc(C(C)C)n1 +CN(CC(N)=O)C(=O)c1cc(-c2cccc(Cl)c2)on1 +Cc1nccc(NC(C)c2ccc(Br)cc2)n1 +N#CCc1ccc(NC(=O)N(Cc2ccccc2)CC2CCCO2)cc1 +CCOc1ccc(S(=O)(=O)NC2CC2)cc1NC(C)=O +Cc1ccc(C)c(OCCC(=O)NC(C)(C)CO)c1 +COc1ccccc1C=c1sc(=CC(=O)c2ccco2)n(C)c1=O +N#Cc1cccc(S(=O)(=O)NCC2(c3ccc(F)cc3)CC2)c1 +Cc1cc(-c2nnc(CCC(=O)N(C)Cc3ccccc3)o2)n(C)n1 +O=C(COc1ccccc1Br)NCc1ccccc1F +CCOC(=O)C1CCN(S(=O)(=O)c2ccc(OC)c(F)c2)CC1 +O=C(NCC1CCC1)c1ccccc1Br +Cc1cnn(CC2CCCN2C(=O)c2c(C)nn3cccnc23)c1 +CC(CNc1oc(-c2cccc(F)c2)nc1C#N)N1CCOCC1 +CC(=O)N1CCC(C2NCCc3c(F)cc(F)cc32)CC1 +Nc1nc(=O)n(C2OC(CO)C(O)C2O)c2ccccc12 +c1cc(NCc2cccs2)cc(-c2cnco2)c1 +O=C(NCc1cccc(C(F)(F)F)c1)NC1CC1 +Cc1[nH]c(SCC(=O)N2CCOCC2)nc1Cc1ccccc1 +CC(C)(C)C1CCCN(C(=O)Cc2ccc[nH]2)CC1 +CCOC(=O)CC1CCCN(C(=O)OCc2ccccc2)C1 +Cc1cc(C)cc(CCNC(=O)N(C)Cc2cnn(C)c2)c1 +CC(C)C(NC(=O)c1ccco1)C(=O)N(C)Cc1cscn1 +CCCc1ccc(S(=O)(=O)NCCc2ccccn2)cc1 +CCc1cc(NC(C)COCC(F)(F)F)n2ncnc2n1 +CCOC(=O)C1=C(C)C(C(=O)N2CCC(C)CC2)C(C)=N1 +CNS(=O)(=O)c1ccc(C(C)NCCc2ccccn2)cc1 +Cc1ccc(C(=O)N2Cc3ccccc3CC2C(N)=O)c(C)c1 +CC(Cn1cccn1)NC(C(=O)N1CCCCC1)c1ccccc1 +CC(=O)Nc1cc(NCc2ccc3c(c2)CCO3)ccc1C +O=S(=O)(Nc1ccccc1F)c1ccccc1 +COc1cc(C)c(S(=O)(=O)NCc2ncoc2C)cc1OC +Cc1ccc(-n2nnnc2SCC(=O)NC2CCOCC2)c(C)c1 +C#CCNC(=O)C1CC(=O)N(c2ccc(Br)cc2C)C1 +CSc1ccc(C(=O)N2CCC(C)CC2C)cn1 +O=C(CSc1ncn[nH]1)Nc1cccc(Br)c1 +CCOC(=O)C(O)(c1ccc(O)c(CC)c1)C(F)(F)F +CC(CO)(CO)Cc1ccc(Br)cc1 +COc1ccccc1Cn1c(C)ccc(C#N)c1=O +CCc1c(C#N)nnn1-c1ccc(Cc2ccncc2)cc1 +Cc1nc2cc(C(=O)N3CCCC3c3nc(C(C)C)no3)ccc2[nH]1 +Cn1c(Nc2ccccc2Cl)cc(=O)n(C)c1=O +O=C1CN(C(=O)COC(=O)c2ccccc2-c2ccccc2)CCN1 +CCCCC(=O)Nc1ccc(C)cc1NC(=O)c1ccoc1C +CCCN1CNc2c(c(=O)[nH]c(=O)n2-c2ccccc2OC)C1 +CC(=O)N1CCCC(C(=O)Nc2ccccc2Cc2ccccc2)C1 +COc1ccc(C)cc1-n1nnnc1SCC(=O)NC(C)(C)C +Cc1cc(C)c(OCC(=O)N(CCO)CCO)cc1C +CC(C)N(C)C(=O)C1CCN(C(=O)NCCN2CCOCC2)CC1 +Cc1nc(C)c(CC(=O)OCc2ccc(F)cc2)c(=O)[nH]1 +CCOC(=O)CNC(=O)c1cccc(OC(F)F)c1 +CC(=O)NCC(=O)NCC(=O)Oc1ccc(Cl)cc1C +COC(=O)NCC(=O)NC(C)CN(C)c1ccccc1 +CC(C)c1nc(C(C)NC(=O)C2(c3ccccc3)CC2)cs1 +Cn1ncc2c1ncn1nc(-c3n[nH]cc3Br)nc21 +COc1ccc(-n2nc(-c3ccco3)nc2C2(C(N)=O)CC2)cc1 +O=C(CNC(=O)c1cc[nH]n1)NCC(F)(F)F +COc1ccc(NC(=O)OC(C)(C)C)c(NC(=O)Cc2ccc[nH]2)c1 +O=C(COc1ccccc1Cl)NCC1COc2ccccc2O1 +OCCCn1nnc(CO)c1Cc1cccs1 +COC(C(=O)N1CCc2ccc(F)cc21)c1ccccc1 +CCCc1nc(CSc2nc(C)cc(C)c2C#N)no1 +O=C(c1ccccc1SC(F)F)N1CCC2(CC1)OCCCO2 +COc1cccc(C2CN(Cc3cccc4c3OCO4)CCO2)c1 +Cc1n[nH]c(C2CN(CC(=O)N(C)Cc3ccsc3)CCO2)n1 +COc1cc(F)c(C(C)NC(=O)c2cccc(C)n2)cc1OC +COC(=O)Cc1csc(NC(=O)c2ccc[nH]2)n1 +Cc1cc(NC(=O)CCCSc2ccc(Cl)cc2)on1 +Cc1cccc(OCC(O)CNc2cccc(F)c2)c1 +CC(C)COC(=O)N1CCN(Cc2cnc3cnccn23)CC1 +Cc1ccc(S(=O)(=O)N(C)c2ccc(N)cc2C)cc1 +O=C(c1ccno1)N1Cc2[nH]nc(COCC3CC3)c2C1 +O=C(Cc1ccc2c(c1)OCO2)N1CCC(O)(C(F)(F)F)CC1 +CC(C)c1noc(CSc2ncccc2N)n1 +CC1CC1CNC(=O)NCc1ccccc1OC(F)F +Cc1cc(C)c(S(=O)(=O)N(C)CCO)c(C)c1 +Cc1cc(C(=O)Nc2ccc(NC(=O)C3C=CC=N3)cc2)co1 +CN(CCOc1ccc(Cl)cc1)C(=O)CNS(C)(=O)=O +CC1CC=CCC1COC(=O)C1CC(=O)N(Cc2ccco2)C1 +CCc1c(C)noc1-c1cnc(NC(C)C)nc1-c1cnc(C)cn1 +CN1C(=O)CC(C(=O)Nc2cccc(F)c2C#N)C1c1cccnc1 +Cc1ccccc1C(C)NC(=O)Nc1ccc2c(c1)CCC(=O)N2 +CC(C)COc1ncccc1C(=O)Nc1nnc(CC(C)C)s1 +CCOc1ccc(NC(=O)N(C)C(C)CC#N)cc1C +CCCC1CN(C(=O)c2cccnc2Nc2cccc(F)c2)CCO1 +CCOc1cccc(NC(=O)NCc2cccc3cccnc23)c1 +Cc1ccsc1C(=O)N1CCOCC1C1CC1 +COc1c(NC(=O)c2cc3ccccc3s2)c(C)nn1C +COCCN(Cc1ccc(C#N)cc1)Cc1cnc2ccc(C#N)cn12 +CN(C(=O)COC(=O)c1ccc(N)cc1)C1CCCCC1 +O=C(OCCn1cncn1)c1cccc(-c2ccoc2)c1 +CCCC(=O)N1CCN(c2nc(CC)nc3sc(C)c(C)c23)CC1 +CCCS(=O)(=O)NCC(C)(OC)c1cccc(Cl)c1 +CC(C)(O)CNC(=O)c1cc2ccccc2oc1=O +Cn1cnc2cc(C(=O)N3CC4CCCCC43c3ccccc3)cnc21 +O=S(=O)(NCc1ccoc1)c1ccc(C(F)(F)F)cc1 +O=C(NCc1ccccn1)c1csc(Nc2cccnc2)n1 +Cc1noc(C(C)C)c1C(=O)NCc1ccc(OCC2CC2)nc1 +O=S(=O)(Nc1cccc(-c2ccn[nH]2)c1)c1ccc(F)c(F)c1 +O=C(Nc1ccc(N2CCCC2)cn1)c1cnc2sccn2c1=O +Nc1cccc(S(=O)(=O)NC(C2CC2)C2CC2)c1 +CC(=O)Nc1cc(OC(C)=O)c2ccccc2c1OC(C)=O +O=C(Nc1ccccc1N1CCC(CO)CC1)c1n[nH]c2c1CCC2 +CN(Cc1ccccc1)c1ccc(C(F)(F)F)cn1 +O=S(=O)(c1ccccc1)N1CCCc2ccccc21 +NS(=O)(=O)c1ccc(Cn2ccnc2C2CCCCC2)cc1 +NS(=O)(=O)N1CCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1ccc(C(O)CNc2c(C)cccc2C(C)C)cc1N +CCC(=O)N1CCOc2ccc(S(=O)(=O)NCCO)cc21 +Nn1c(COc2ccccc2)nnc1SCCn1cccn1 +CNC(=O)CSc1nnc(-c2ccccc2)n1CC1CCCO1 +Cc1cc(NC(=O)c2csc(Cc3ccccc3)n2)no1 +Cc1ccc(NC(=O)c2c(-c3cccnc3)cnnc2N)cc1 +CN1CCN(C(=O)C2CCN(c3cccc(Cl)c3)CC2)CC1 +CCC(=O)N1CCCN(C(=O)CCc2cccnc2)CC1 +Cc1cc(C(=O)N2CCC(C(N)=O)CC2)sc1C +O=C(Nc1ccncc1)N(CCCO)C1CCc2ccccc21 +O=C(Nc1cccc(F)c1)N1CCC(CO)CC1 +COc1ccc(CC(=O)NC(C#N)CC(C)C)cc1 +COc1ccnc(NC(=O)c2ccc(-n3cnnc3)cc2)c1 +O=C(CN1CCN(c2ncccn2)CC1)N1CCC1c1cccs1 +COCCOc1ccc(NC(=O)c2c(C)[nH]c3ccccc23)cc1 +CCCNC(=O)c1ccc(Cl)c(NC(=O)N2CCC(O)C2)c1 +CC(=O)NC1C(=O)N(CCCOC2=CC=C(C)CC2)c2ccccc21 +Cc1csc(N2CCN(C3CCOC3=O)CC2C)n1 +Nc1oc(C(F)(F)F)cc1C(=O)c1cccnc1 +CCCCC(=O)OCC(=O)Nc1c(C)cc(C)cc1C 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+Cc1ccnc(NC(=O)c2ccccc2NC(=O)C(C)(C)C)c1 +CC(C)CN1CCOC(CNC(=O)COc2cccc(Cl)c2)C1 +NC(=O)CSc1ncnc2cc(-c3ccc(Cl)cc3)sc12 +Cc1ccccc1CNC(=O)c1ccc(F)c(F)c1 +CC(=O)NCCCCCC(=O)N1CCCCC1CO +Cc1cc(C)nc(C(C#N)C(=O)c2cc3c(s2)CCC(C)C3)n1 +Cn1cc(S(=O)(=O)N2CCCC2CC2CCCCC2)cn1 +O=C1COc2cc(NC(=O)c3csc(-c4ccco4)n3)ccc2N1 +CCc1ccccc1OC1CN(c2cc(N)ncn2)C1 +CC(=O)Nc1cccc(NCCCc2nc(C)no2)c1C +COc1ccc2c(c1)OCC(Cc1ccc(CC(N)=O)cc1)C2 +Cc1ncc(C(=O)NCCNc2ncccc2C(F)(F)F)s1 +Cc1ccsc1C(=O)NC(C)Cc1cccs1 +Cc1ccc(CN2CCC3(CCN(c4cnn(C)c4)C3=O)C2)s1 +CCOc1ccc(C#N)cc1NC(=O)NC(C)C1CC1 +CCCOC(=O)C(C)n1c(C)ccc(C(C)=O)c1=O +Cc1nc(C(=O)Nc2ccc(Cl)c(C(F)(F)F)c2)co1 +CN(CC(=O)NCc1ccco1)C(=O)c1ccc2ccccc2c1 +COc1ccc(Cl)cc1NC(=O)c1cn(CC(=O)N(C)C)nn1 +Cn1nnnc1Sc1ccc(N)c2cnccc12 +Cc1ccc(SCC(F)(F)F)c(NC(=O)c2cnc(C)cn2)c1 +O=C(CC1Oc2ccccc2NC1=O)OCC1CCCCC1 +CNC(=O)C12CC3CC(C1)CC(C(=O)NC)(C3)C2 +CCCC(C)(O)C(=O)NC1CC(=O)N(C)C1c1ccc(Cl)cc1 +CC(Sc1n[nH]c(=O)n1C1CC1)c1ccccc1 +CCC(C)C(NC(=O)C1CCC(C)CC1)C(=O)Nc1cccc(C)n1 +CCOc1ccccc1-n1nnc(CO)c1Cc1cccs1 +NC(=O)c1ccc(NC(=O)N(Cc2cccs2)C2CC2)cc1 +Cc1cc(C(=O)Nc2nc3ccc(Br)cc3s2)no1 +Cc1ccc(O)c(C(=O)NCC(=O)OCc2ccccc2)c1 +COC(=O)C1CCN(C(=O)CCNC(=O)c2ccsc2)CC1 +CCn1c(CCNC(=O)c2ccccn2)nc2ccccc21 +COC(=O)CC(C)NC(=O)c1c(C)oc2ccc(OC)cc12 +C=CCC1C=CCC(CC=C)N1C(=O)c1cnc(CC)nc1 +OC(c1ccccc1)C1NCCc2cc3cc[nH]c3cc21 +CC(C)n1cc(N2CC(C(=O)NCc3ccccc3)CC2=O)cn1 +CC(C)NC(=O)Nc1cccc(C(=O)N(C)CCc2ccccc2)c1 +CCOCC1CCN(C(=O)N=c2[nH]nc3ccccn23)C1 +COCCN1CCN(c2ccc(Cl)cc2)CC1 +NC(=O)c1ccc(C#CCNC(=O)NCc2ccc(Cl)cc2)cc1 +Cc1ccc(NC(=O)c2scnc2C2CC2)c(N(C)C)n1 +COc1ccc(Oc2nnnn2-c2ccccc2)c(N)c1 +CN(CC(=O)Nc1ncn(Cc2cccnc2)n1)C(=O)OC(C)(C)C +O=C(NCc1nc(C2CC2)cs1)Nc1ccc2c(c1)COC2 +CCCOc1nc(CC)nc(NC2CCCC2)c1N +CC1CN(C(=O)CNc2cccc3ccccc23)CCO1 +Cc1nccc(CNC(=O)c2ccc(-c3ccco3)nc2C)n1 +CC(C)Cc1noc(C(C)Nc2nc(C(C)C)nc3c2cnn3C)n1 +Cc1ccc(C(CNCc2ccco2)N2CCOCC2)cc1 +Cn1nc(C(=O)NCCCOCC2CCCO2)ccc1=O +Cn1c(=O)ccn(CC(=O)NCCN2CCOCC2)c1=O +CC(NC(=O)COc1cccc2cccnc12)c1ccc(F)cc1 +COc1ccc(CNC(C)C(N)=O)c(OC)c1OC +Cn1cc(S(=O)(=O)NC(C2CC2)C2CC2)c(N)n1 +COc1ccnc(N2CCN(C(=O)c3ccc(C)nc3)CC2)n1 +Cc1ccc(C(CNC(=O)Cn2cccn2)N2CCOCC2)o1 +Cc1cc(CNc2ccc(Cl)cc2NC(=O)c2ccco2)no1 +COc1ccc2cc(NC(=O)c3cc(C(C)C)on3)cnc2c1 +Cn1ccc(C(=O)NCCOc2ccc(C(C)(C)C)cc2)cc1=O +CC1CCc2sc(C(=O)Nc3ccc4c(c3)OCC(=O)N4)cc2C1 +COc1ccc(C(=O)Nc2cccc(F)c2)cc1N +CCC(C)C(C(=O)Nc1cn[nH]c1)c1ccccc1 +O=C(CNC(=O)c1ccc(F)cc1)NC1CCCCCC1 +CCc1cccc(NC(=O)C2COc3ccccc3O2)c1 +CC(NC(=O)CSc1nncn1C)c1ccc(Cl)cc1Cl +CCc1nnc(NC(=O)NC(C)COc2ccc(F)cc2F)s1 +CCC(C)C(NC(=O)Cc1ccc2ccccc2c1)C(N)=O +CC(C)CCN1C(=O)Cn2cccc2C1C(=O)NC1CCCCC1C +COCC(C)NC(=O)CNc1cc(F)c(F)c(F)c1 +Cc1ccc(C)c(C(=O)N2CCSc3ccc(N)cc32)c1 +CCCC(NC(N)=O)C(=O)N1CCc2sccc2C1 +COc1ccc(C(=O)N(C)Cc2ccccc2N2CCCCC2)cc1 +c1csc(N2CCCN(c3nc(C4CC4)no3)CC2)n1 +C#CCN1CCN(CC(=O)Nc2cc(C(C)(C)C)nn2C)CC1 +O=C(C1CCOCC1)N(Cc1ccncc1)Cc1cccnc1 +CC(OC(=O)c1ccn[nH]1)c1ccc(F)c(Cl)c1 +O=C(NCCN1CCOCC1)c1cc2c([nH]c1=O)CCCC2 +O=C(Nc1ccc2c(ccn2CCN2CCOCC2)c1)C1CC1 +Cc1ccc2[nH]c3c(NCCN4CCOCC4)ncnc3c2c1 +COc1ccccc1N1CC(c2nc3ccc(C)cc3[nH]2)CC1=O +NC(=O)C1CCCN(S(=O)(=O)c2cccc(Cl)c2)C1 +CCCN1CCN(S(=O)(=O)C2=Cc3ccccc3CC2)CC1 +CNC(=O)CNc1cccc(OCc2ccccc2)c1 +CC(C)(CNC(=O)c1noc2c1CCCC2)c1ccncc1 +COc1ccccc1CC(=O)N1CC(C)CC(C)C1 +Cc1cc(C(=O)NC2CCCC2)ccc1NC(=O)c1ccc(F)nc1 +CCCC(=O)N1CCC(NC(=O)c2cccnc2)CC1 +CC(C)S(=O)(=O)N(C)CC1COc2ccccc2O1 +CC(NC(=O)c1ccnc(N)c1)c1ccccc1F +COc1ccccc1C(=O)N1CCCC(Cc2nccs2)C1 +CC(NS(=O)(=O)c1cccc2cnccc12)C1CC1 +CC(Sc1ccccn1)C(=O)c1c[nH]c2ccccc12 +COc1ccccc1Cn1c(=O)oc2ccc(Cl)cc21 +CCCN(CCC)C(=O)c1sc2nc3n(c(=O)c2c1C)CCCC3 +Cc1oc(C(=O)N2CCN(c3ccccc3)CC2)cc1S(N)(=O)=O +Cc1cc(=O)[nH]c(SCc2cc(-c3ccco3)on2)c1C#N +CN(C)c1ccc(C#CCNC(=O)c2cnn(-c3ccccc3)n2)cc1 +COC(=O)c1cccc(C(=O)N2CCC(O)(C(F)(F)F)CC2)c1 +N#Cc1ccc(Cl)c(NC(=O)C2CCCN(C(=O)C3CC3)C2)c1 +CC(C)N1C(=O)C(Cc2ccccc2)Oc2cc(O)ccc21 +CN(C)C(CNC(=O)NCc1ccc2c(c1)OCO2)c1cccs1 +CN(C(=O)c1ccc(S(C)(=O)=O)cc1)c1cccc2ncccc12 +CNC(=O)c1ccc(NC(=O)CCCOc2ccccc2)cc1Cl +CN(C)c1ccccc1C#CCNC(=O)c1ccc2cc[nH]c2c1 +CCOC(=O)CN(CC)C(=O)c1ccc(OC)cc1O +Cc1nn(C)c(C)c1CNC(CO)Cc1ccccc1 +COc1ccc(CN2CCN(C(=O)c3ccc(C)nc3C)CC2)cc1 +O=C(NCC(c1ccccc1)c1ccccc1)c1ccccn1 +CCc1nnc(SCC(=O)c2ccc(OC)c(OC)c2)n1N +CCc1c(C(=O)N2CCOCC2)c(CC(C)C)nn1C +CC(=O)Nc1ccc(Oc2ncc(C)cc2N)cc1 +O=C(Cn1c(=O)oc2ccccc21)Oc1cccc(Cl)c1 +CNC(=O)c1cccc(OC(=O)c2ccc(C)s2)c1 +CCCS(=O)(=O)N1CC2CCC1C2OCc1ccccn1 +C=CCNC(=O)Cn1c(-n2nc(C)cc2C)nc(CCC)cc1=O +Nc1cc(F)ccc1SCCN1CCNC1=O +COCCNC(=O)c1ccc(NC(=O)c2ccccc2C)cc1 +CC(C)CCC(=O)Nc1nc(C(F)(F)F)cs1 +NC(=O)C(NCc1ccc(Br)cc1)c1ccccc1 +Cc1cccc(=NS(=O)(=O)c2ccc3ccccc3c2)[nH]1 +COc1ccccc1NC1CCN(C(=O)c2cc(C#N)c[nH]2)CC1 +Cc1ccc(NC(=O)c2cc(C)no2)c(OCC(=O)N(C)C)c1 +NS(=O)(=O)c1cnc(N2CCCC(CO)C2)s1 +Cc1cc(C(=O)N(C)CC(F)F)ccc1NC(=O)OC(C)(C)C +Cn1ccnc1COC(=O)c1ccnc(OC2CCC2)c1 +Cn1cc(C(=O)N2CCCC2c2cccc3c2OCCO3)ccc1=O +CCOCCNC(=O)C1CCN(S(C)(=O)=O)CC1 +CC(=O)c1cccc(NC(=O)CCSc2ccc(F)cc2)c1 +O=C(CCc1cccnc1)NCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +O=S1(=O)COCCN1Cc1cnn(-c2ccccc2F)c1 +Cc1ccc(NC(=O)Cn2cc(Br)ccc2=O)nc1 +CS(=O)(=O)NCC1CCOC1c1ccccc1 +O=C(Nc1nc(C2CCCCC2)n[nH]1)NC1Cc2ccccc2C1 +O=C(Cn1cc(C2CC2)nn1)Nc1ccc(Oc2cccnc2)nc1 +CC(C)Cc1ncc2c(n1)CN(C(=O)CC1=CCCCC1)C2 +COC1OC(COC(=O)c2ccccc2)C2OC(C)(C)OC12 +COc1c(C)cccc1C(=O)N1CCC(N2CCCC2=O)CC1 +COc1ccc(NC(=O)CCCC(=O)N(C)C)cc1Cl +COCCCN(C)C(=O)Nc1ccc(S(=O)(=O)C(F)F)cc1 +CC(=O)c1ccc(NC(=O)Cc2c[nH]c3ncccc23)cc1C +CC(C)NC(=O)c1sccc1S(=O)(=O)NCc1cccs1 +NC(=O)c1cc(NCC(=O)N2CCOCC2)ccc1Cl +COCCN(c1ccccc1C(C)=O)C(C)C1CC1 +COc1ccc(OC)c(NC(=O)Cc2cccc(N)c2)c1 +O=C(c1cccs1)N1CCC(c2noc(-c3cccnc3)n2)CC1 +Cc1nc[nH]c1-c1nccn1CCN(C)S(C)(=O)=O +CCOC(=O)c1ccc(-c2ccc(OC)cc2)nc1C +O=C(COC(=O)c1cc(F)c(Cl)cc1Cl)NC1CC1 +CC(C)Oc1ccc(C(C)NC(=O)N(C)Cc2ccncc2)cc1 +CNC(=O)c1cccc(NC(=O)CNC(=O)C2CCCCC2)c1 +COCCNC(=O)c1cccc(OCC2CCCO2)c1 +CC(C)c1nnnn1CC(=O)Nc1ccc(Cl)cc1F +COc1ccccc1C(C)NC(=O)c1ccc2c(c1)OCCO2 +O=C(NCc1cnn2ccccc12)NC1CCCC1 +CN(C(=O)Cn1cnc2c(cnn2C)c1=O)c1cccc2ncccc12 +CN(CCn1cccn1)S(=O)(=O)c1ccc(C#N)cc1 +CCN1C(=O)Cc2cc(NC(=O)C3(c4cccs4)CC3)ccc21 +CC(C)(C)c1cn2nc(NCCCc3n[nH]c(N)c3C#N)sc2n1 +O=C(Nc1nc(-c2ccc3c(c2)CCO3)cs1)c1cccs1 +Cc1nn(C(C)(C)C)c2nc(N)c(C(=O)NC3CC3)cc12 +C=CCn1c(SCc2nnc(C)o2)nnc1-c1ccoc1C +COc1ccc(C2CCCN2C(=O)c2cnc3ccccn3c2=O)cc1 +CCCN(CC(=O)OCC)C(=O)c1ccc(C)c(F)c1 +CC(C)CN1CCOC(CNCc2ccccc2C(F)(F)F)C1 +Cn1nccc1C(=O)N1CCC(c2nc(C3CCCC3)no2)C1 +C#CCN1CCC(C(=O)Nc2cccc(CN(CC)C(C)=O)c2)CC1 +Cc1cc(C)cc(NC(=O)CC(C)n2ccnc2)c1 +CCOC(=O)NCC#Cc1ccc(C(=O)N(C)C)cc1 +CN(Cc1cc(Br)cs1)C(=O)Cc1ccccc1 +O=C(NCCc1ccco1)C1CCCN(c2ccc3nnnn3n2)C1 +Cc1cccc(N2CCC(C(=O)NCc3ccc(F)cc3)C2=O)c1 +Cc1noc(CCC(=O)Nc2ccccc2Cc2ccccc2)n1 +O=C(C1CC2OCCC2N(C(=O)c2cccnc2)C1)N1CCCC1 +COCCN1CCN(C(=O)c2ccc3nncn3c2)CC1=O +OCC1OC(N2CCc3ccccc32)C(O)C(O)C1O +O=C(c1ccccc1Br)N(Cc1ccsc1)C1CC1 +CCn1ncc(CN2CCOC(CCCc3ccccc3)C2)c1C +Cc1cc(C)n(CC(=O)Nc2cnn(Cc3ccccc3)c2)n1 +COc1ccc(CCNC(=O)c2cc(=O)c(OC)c[nH]2)cc1 +CC1CN(c2nncc(-c3ccc4ccccc4c3)n2)CC(C)O1 +Cc1ccn2c(=NC(=O)c3ccc(C(N)=O)nc3)[nH]nc2c1 +O=C(Nc1ccc(Cl)cn1)c1cccc(F)c1 +CCC1CN(C(=O)c2ccc(-c3cnn(C)c3)nc2)CCN1C(C)C +O=C(C1CC1)N1CCCC(c2nnc(Cc3ccccc3)s2)C1 +Cc1nnc(CN(CCc2ccccc2)Cc2ccccc2)o1 +Cc1n[nH]c2oc(N)c(C(=O)c3ccc(F)cc3)c12 +CC1CN(S(=O)(=O)c2ccc3ccccc3c2)CC(C)O1 +CCS(=O)(=O)NC1CC(=O)N(c2ccc(Cl)cc2)C1 +N#Cc1ccc(Cl)cc1NC(=O)Cc1ccccc1 +Cc1nc(NCC2CCc3nncn3C2)c2c(C)c(C)sc2n1 +Cc1noc(-c2ccc(C(=O)OC(C(N)=O)c3ccccc3)cc2)n1 +CCCn1nc(C(=O)OC2CCCC(C)C2)ccc1=O +Cc1ccccc1NS(=O)(=O)c1cc(Br)cnc1N +CCCn1cc(NC(=O)C2CC=CCC2)ccc1=O +O=C1CC(c2ccccc2)N(C(=O)c2ccc3nccnc3c2)CCN1 +CC(=O)Nc1cccc(NCc2ncc(-c3ccccc3Cl)o2)c1 +O=C(c1ccccc1)C1CCN(C(=O)Cc2ccsc2)CC1 +Cc1nn(C)c(C)c1C(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +COc1cc(C#N)ccc1OCC(=O)N1CCCC1c1cnn(C)c1 +CN(CC(=O)N1CCCC1)c1cc(Cl)ccc1C#N +Cc1nc(CC(=O)OCC(=O)NC2(C#N)CCCC2)cs1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)NC1CCCC1 +CC(NC1CCN(c2ccc(F)c(Cl)c2)C1=O)c1ccccn1 +Cc1ccc(NC(=O)Cn2cc(Br)c(=O)[nH]c2=O)nc1 +O=S1(=O)N=C(NCc2ccccc2Cl)c2ccccc21 +COCC(=O)Nc1ccc(C(=O)Nc2ccccc2)cc1 +Cc1nc2sc(C(=O)OCC(=O)c3ccc[nH]3)c(C)c2c(=O)[nH]1 +CC(=O)c1ccc(-c2ccccc2)n(C2CC2)c1=O +COC(=O)c1oc(CSc2nnnn2C)cc1C +O=C(c1sccc1C1CC1)N1CCC(c2nnc3n2CCC3)CC1 +COCCn1nc(C(=O)NC2CCCCNC2=O)ccc1=O +CCc1cc(C(=O)Nc2ccc(NC(=O)c3cnoc3C)cc2)[nH]n1 +CCC(CCO)NC(=O)Nc1c(C)cc(Br)cc1C +CCOCCCNC(=O)c1c(C)nn2c(C)cc(C)nc12 +CC(=O)c1ccc(OCC(C)C)c(NC(=O)C2CCC2)c1 +CCSc1nc(C(C)C)nc2c1c(=O)n(C)c(=O)n2C +Cc1nccc(-c2cccc(NC(=O)c3ccc(F)cc3Cl)c2)n1 +COCCCN(C)S(=O)(=O)c1ccc2c(c1)CCC2 +O=C(Oc1ccccc1)C1CC(=O)N(Cc2ccccn2)C1 +O=S(=O)(Nc1ccccc1)c1cccc(Br)c1 +CCc1nc(C2CCCN(C(=O)c3cnn(CC)c3)C2)no1 +CCCC1CCCN(C(=O)C(NC(C)=O)C2CCCC2)CC1 +Cc1ccccc1C(=O)Nc1cc(N2CCCS2(=O)=O)ccc1F +CCC(COC)NC(=O)c1cc(-c2ccc(O)cc2)n[nH]1 +COCCNc1nnc(SC(C)c2ccc(F)cc2F)s1 +Cc1ccc(CN(C(=O)c2ccc(-c3ccco3)[nH]c2=O)C2CC2)o1 +COc1cc2cnccc2c(NCCCN2CCOCC2)c1OC +O=C(CN1CCCc2cc(F)cc(F)c21)Nc1nncs1 +NS(=O)(=O)NCc1ccc(OCC(F)(F)F)nc1 +CCSc1nc(=O)c2c(n1C)NC(=O)CC2c1ccccc1C +O=c1ccc(CNc2cccc3cccnc23)c[nH]1 +COc1ccc(OC)c(C(=O)NCc2nnc(-c3cccs3)o2)c1 +Cc1csc(C(=O)NCC#Cc2ccc(N3CCOC3=O)cc2)c1 +Clc1ccc(-c2cnnc(N3CCCCCC3)n2)cc1 +COCCN(CC1CC1)C(=O)c1[nH]nc(-c2ccccc2)c1C +CCc1onc(C)c1NC(=O)NCC(C)c1ccc(F)cc1F +Cc1nc(CNC(=O)NC2CCC(O)CC2)oc1C +CC1CC(c2ccc(F)cc2)CN1C(=O)C1(NC(N)=O)CCCCC1 +Cc1sc2ncnc(NC(C)C3CCCO3)c2c1C +CSc1ccccc1NC(=O)NCCC(=O)NC1CCCCC1 +CC(C)CC(=O)N1CCc2nc(NC(=O)c3ccoc3)sc2C1 +CC(C)OC(=O)c1nnn(CC(=O)NCc2ccccc2)c1N +COC(=O)C1CCCCCC1NC(=O)c1cc2c(C)nn(C)c2s1 +OCc1c(-c2ccccc2)nc2c(Cl)cccn12 +Cn1cccc1C(O)CNC(=O)C1CCCCC1 +Cc1cc(C(=O)NCCOc2ccc3c(c2)CCC(=O)N3)[nH]n1 +Cc1nn(C)c2c(=O)n(CC(=O)NCCC3=CCCCC3)ccc12 +Cc1ccc(F)c2c1N(C(=O)C1CCOCC1)CCC2 +Cc1ccc(OC2CCN(C(=O)Cc3ccc[nH]3)CC2)cc1 +C#CCN1CCN(C(=O)c2cc(Br)ccc2Cl)CC1 +COC(=O)C1CCN(C(=O)Nc2cccc(OC)c2)CC1 +Cc1ccc(-c2nnc(CCC(=O)Nc3cc(C)on3)o2)cc1 +CC(=O)NCCCNC(=O)c1nc(-c2cccs2)oc1C +O=C(COc1ccc2c(c1)OCO2)N1CCCC(c2ccn[nH]2)C1 +CC(=O)NC1CCCN(C(=O)NCCCSc2ccccc2)C1 +O=C(CSc1nnc(Nc2ccccc2)s1)NCc1ccco1 +c1ccc(-c2ccnc(Nc3nc(-c4cccnc4)n[nH]3)n2)cc1 +Cc1nc2cc(N(C)C(=O)COc3cccc(Cl)c3)ccc2[nH]1 +CCc1noc(COc2ccc(C(=O)NC3CC3)cc2)n1 +CNC(=O)c1cc(C)ccc1NC(=O)CSc1ccncc1 +Cc1nc(-c2cc(C(=O)NC(C(N)=O)C(C)(C)C)co2)cs1 +COC(=O)c1ccc(S(=O)(=O)NCC2CCOC2)cc1 +C#CCN1CCC(C(=O)NC(C)c2cccc(C(F)(F)F)c2)CC1 +COC(=O)Cc1cccc(NC(=O)c2scnc2C2CC2)c1 +Cc1nnc(SCCOc2ccc(Cl)cc2Cl)n1N +Clc1cc(NCc2nnc(C3CC3)o2)ccc1-n1cccn1 +C=CCOC(=O)CCC(=O)Nc1cccc2ccccc12 +CCNC(=O)C1CCN(c2cccc(F)n2)CC1 +c1ccc(Cc2noc(CN(Cc3ccco3)C3CC3)n2)cc1 +CC(C)(C)c1ccc(CNC(=O)c2cncc3cnccc23)cc1 +O=C(NCCCn1ccnc1)c1n[nH]cc1Cl +COc1cc(-n2nc(C)c3ccccc32)ccc1N +Nc1cc(Cl)cc(Br)c1OC(F)F +Cc1nn(C)c(C)c1CCC(=O)NCC(C)c1cccs1 +Cc1ccc(C)c(-c2csc(NC(=O)c3cccnc3)n2)c1 +Cc1ccc(NC(=O)CCCOc2ccc(S(C)(=O)=O)cc2)nc1 +O=C(Nc1nc[nH]n1)c1ccc(-c2ccc(Br)cc2)s1 +CCc1nn(-c2ccccc2Cl)c2c1CNCC2 +CCCNc1nc2c(c(=O)n(C)c(=O)n2C)n1CCC(C)C +CC(C)(C)OC(=O)NC1CCCC1C(=O)N1CCC(O)C1 +CCn1cc(C#N)c(=O)n(Cc2ccc(F)cc2C(=O)OC)c1=O +Cc1cc(C)n(C(C)c2ccccc2)c(=O)c1C#N +CC(C)CCNC(=O)Cn1c(=O)n(C)c(=O)c2sccc21 +CCCCCC(=O)NCCc1nnc2ccccn12 +NC(=O)c1cc(NCc2cc(Br)ccc2F)ccc1F +CCOc1cc(Cl)ccc1S(=O)(=O)Nc1ccccc1O +O=C(CCCC(=O)c1cccs1)Nc1cccc2ncccc12 +COC1CCCN(C(=O)c2c[nH]nc2-c2cccc(Cl)c2)C1 +COC(=O)c1sc(NC(=O)CC2CCCC2)nc1C +CN(C)c1ccc2nc(C(=O)Nc3ccc(F)cc3)oc2c1 +O=C(NCc1nc2cccnc2n1Cc1ccccc1)C1CCC1 +NC(=O)c1cccnc1N1CCN(CCOC2CCCCCC2)CC1 +N#CCOc1cccc(CC(=O)N2CCCC(CCC(N)=O)C2)c1 +C#CCN1CCN(C(=O)NCC(C)Oc2cccc(Cl)c2)CC1 +CCCC1CCc2nc(NC(=O)Cn3ccc(=O)[nH]c3=O)sc2C1 +CCC1CCCN(C(=O)NCc2ccc(-n3cncn3)cc2)C1 +CN(C(=O)CCc1ccc(C#N)cc1)c1cccc2ncccc12 +CCCC(=O)N1CCCC1C(=O)N1CCCC(NC(C)=O)C1 +O=C(COc1cncc(Br)c1)Nc1cccc2[nH]cnc12 +NC(=O)c1cccc(COC(=O)Cc2ccc(F)cc2)c1 +C=CCNC(=O)C(C)N1CCN(S(N)(=O)=O)CC1 +CCNc1ncc(C(=O)Nc2cnn(C)c2)cc1Cl +O=c1n(Cc2ccccc2)nnn1Cc1ccccc1 +COc1ccc(CN2CCCCCC2=O)cc1Br +CC(c1ccsc1)N1CCN(C(=O)NCc2ncccc2F)CC1 +COc1ccc(NC(=O)C2CCC(=O)N2)cc1Cl +O=C(c1cnccn1)N1CCCC(c2nncn2Cc2ccccc2)C1 +CSc1ccc(C(=O)N2CCC(OCc3ccccc3F)CC2)o1 +O=S(=O)(NCCc1n[nH]c(-c2ccco2)n1)c1ccccc1 +CCOc1ncccc1C(=O)N(C)Cc1ccc(Cl)cc1 +Cc1nc(NCCCSc2nnc(C)s2)c2cnn(C)c2n1 +CCN(C(=O)COc1ccc(N2CCCC2=O)cc1)C1CC1 +CCN(C(=O)c1cc(N2CCCC2=O)ccc1Cl)C1CC1 +Cc1cc(NC(=O)CCCNC(=O)NC2CCCCC2)no1 +Cn1cnc(S(=O)(=O)N2CC3COCC(C2)N3CC2CC2)c1 +COc1ccc(C(=O)CCC(=O)NCc2nc(C)sc2C)cc1 +CCc1onc(C)c1NC(=O)c1cccnc1OCC(F)F +N#CCCN1CCN(c2ncc(Br)cn2)CC1 +COc1ccc(C2(CNC(=O)c3ccncc3)CCCC2)cc1 +CC(NC(=O)c1ccccc1)C(=O)Nc1cccc(O)c1 +COc1ccc(F)c(C(=O)N2CC3CC(O)C(O)CC3C2)c1F +Cc1cc(C)c(NC(=O)CNC(=O)c2ccc(F)cc2F)c(C)c1 +O=C(NCC1CCCO1)N1CCC(C(O)c2ccc(F)cc2)CC1 +CCOc1cc(CNc2nccs2)ccc1OC +CC1CC(C)CN(C(=O)c2ccc(S(=O)(=O)NCCC#N)cc2)C1 +COc1ccc(CNC(=O)COC(=O)c2cc(C)no2)cc1 +Cc1ccc(-c2ccc(C(=O)NC(C)C)c(=O)[nH]2)cc1 +CCCOc1ccc(NC(=O)C2CC(=O)N(C(C)C)C2)cc1Cl +O=C(NCCc1ccco1)c1cc(C2CC2)nc2ccccc12 +O=C1CCCN(S(=O)(=O)c2ccc(F)c(Cl)c2)C1 +O=C(Cc1ccc(O)cc1)NC1CNCc2cccc(Cl)c21 +NC(=O)c1ccc(NC(=O)c2csc3ccccc23)cc1 +CCN(CC)C(=O)C(C#N)Cc1ccc(OC)cc1 +CC(C)c1cc(=O)[nH]c2nnc(SCc3cccnc3)n12 +CCNC(=O)CNC(=O)c1sc2nc(C)nc(C)c2c1C +COCC(NC(=O)CC12CC3CC(CC(C3)C1)C2)C(N)=O +CCCS(=O)(=O)NC1CCN(Cc2cnc(C)s2)CC1 +Cc1cccc2[nH]c(CCC(=O)Nc3ccc4oc(=O)[nH]c4c3)nc12 +N#Cc1ccccc1COc1cccc2cccnc12 +COc1ccc(C(=O)CNC(=O)c2ccc(C)cc2)cc1 +CCCc1nn(CC(=O)NCc2ccccc2)c(=O)o1 +CC(C)(C)OC(=O)N1CCN(C(=O)c2ccc3c(c2)OCO3)CC1 +CC(NC(=O)c1cn(Cc2ccccc2)nn1)C1CCCCC1 +Nc1cccc(C(=O)Cc2nc(-c3ccncc3)cs2)c1 +CCc1ccc(S(=O)(=O)Nc2cnn(C3CCOCC3)c2)cc1 +COCCOc1ccccc1NC(=O)c1cnc2ccccn2c1=O +CCOC(=O)NCC(=O)Nc1cccc(-c2nc(C)cc(=O)[nH]2)c1 +Cc1ccc(CNc2ncn[nH]2)cc1Br +CCC(C)NC(=O)Nc1ccn(Cc2ccccn2)n1 +COC(=O)NCC(=O)OCc1ccc(C(C)(C)C)cc1 +O=C(NCc1ccccn1)c1cc2c(s1)-c1ccccc1CC2 +COc1ccc(C2CCN(S(=O)(=O)c3cnn(C)c3)C2)cc1 +COc1ncccc1C(=O)NC(C)Cn1cncn1 +CC(C)C(C)NC(=O)NC1CCN(c2ccc(C#N)cn2)CC1 +COc1ccc(C(=O)Nc2c(C)nc3ccc(Cl)cn3c2=O)cc1 +O=C(CCS(=O)(=O)c1ccc(Cl)cc1)NC1CCCCC1 +CC(C#N)CNC(=O)c1sc2ccccc2c1Cl +CNS(=O)(=O)c1ccc(C(=O)NCc2cscn2)o1 +Cc1nc(-c2cccc(CNC(=O)c3ccc4c(c3)ncn4C)c2)n[nH]1 +COC(=O)c1cccc(S(=O)(=O)N2CCN(CC(C)C)CC2)c1 +Cc1ccc(C(=O)N2CCCN(C(=O)OCC(C)C)CC2)cn1 +COc1ccc(NC(=O)NCCNc2ncccn2)cc1C +CC(C)CC(CNC(=O)Nc1ccc2c(c1)COC2)N1CCOCC1 +O=C(CCCCCn1cnc2ccccc2c1=O)Nc1ccncc1 +CCOc1ccccc1OCCNc1ccccc1N +CCc1nc(Cn2cnc3c(cnn3-c3ccccc3)c2=O)cs1 +CN(CCCCN1CCOCC1)c1nncc(-c2ccccc2)n1 +COc1ccc(C(O)CCNc2c(C)cc(C)cc2C)cc1 +CC(NC(=O)c1cc2ccccc2[nH]1)C(=O)N(C)C +O=C(NCC1CCCO1)c1cccc(NC(=O)c2ccc(F)cc2)c1 +Cc1cc(C)n(CC2CN(c3nccc(C(F)(F)F)n3)CCO2)n1 +O=C(c1cnccn1)N1CCc2onc(COc3cccnc3)c2C1 +CC(C)c1ccc(C2CC2C(=O)NC2(C#N)CCOCC2)cc1 +Cc1noc(C)c1CC(=O)NCCC12CC3CC(CC(C3)C1)C2 +C=CCn1c(C)nnc1SCCCc1nc2ccccc2o1 +CC(=O)c1cc(C(=O)Nc2ccc(C)c(F)c2)n(C)c1 +CCc1ccsc1C(=O)NCCCN(C)S(C)(=O)=O +Cc1cnn(CC2CCCN2C(=O)c2occc2-c2ccccc2)c1 +CCc1nn(C)cc1CN1CCN(S(=O)(=O)c2cccnc2)CC1 +CCn1nc(C(=O)NC2CCCCCC2C(=O)OC)ccc1=O +CC(C)Oc1ccc(-c2cc(C#N)nn2CCO)cc1 +CCOC(=O)c1nccn1CC(=O)Nc1ccc(C)cc1C +CCc1oc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)cc1C +CN(C)C(=O)CNC(=O)NCCc1ccc(Cl)cc1 +Cc1nnc(NC(=O)CSc2nnc(C)n2CC(C)C)s1 +Cc1ncc(-c2ccc(NC(=O)CN(C)C(=O)OC(C)(C)C)cc2)o1 +COc1ccccc1-c1cc(NC(=O)c2cc(C)nn2C)[nH]n1 +CC(C)N(C)C(=O)NCc1ccccc1OC1CCC1 +Cc1c(C(=O)NCC(C)c2ccc(F)cc2)cnn1C +COC1CCN(C(=O)c2ncccn2)CC1Cc1ccccc1 +Cc1cc2occ(CC(=O)Nc3cccnc3-n3cccn3)c2cc1C +CCc1cccc(C)c1NC(=O)NC1c2ccccc2CC1O +CN(C)C(=O)N1CCN(C(=O)c2ccc(NC(=O)C3CC3)cc2)CC1 +O=C(NCCOc1ccc(-c2cccs2)nn1)c1ccco1 +CC1CCc2oc3ccc(NS(C)(=O)=O)cc3c2C1 +O=C(CNC(=O)c1ccc2c(c1)CCC2)Nc1ccsc1 +CN(CCCNC(=O)c1ccc2c(c1)OCO2)S(C)(=O)=O +Cc1nc2ccccc2n1C(C)C(=O)Nc1cccc(N)c1 +CC(O)CCN(C)C(=O)Nc1ccc(Oc2ncccn2)cc1 +Cc1nnc(NCCCOCC2CC2)c(C#N)c1C +O=C(C1CCOC1)N1CCc2[nH]nc(-c3ccc4c(c3)OCO4)c2C1 +Cc1ccc2ncc(C(=O)N(C)CC(F)(F)F)n2c1 +O=C1CCC(NCc2ccsc2)C(c2cc(F)cc(F)c2)N1 +CC(C)C(NC(=O)Cc1ccc[nH]1)c1nnc2ccccn12 +c1ccc(-n2cc(-c3noc(C4CCCC4)n3)nn2)cc1 +CN(C)c1ccc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)cn1 +CC(=O)OC(C)c1nc(C(C)OC(C)=O)n(C(C)=O)n1 +CSc1ccccc1CN1CCCCC1CCN1CCOCC1 +Cc1ccc2c(c1Cl)CCNC2C(C)(C)CO +COc1cccc(-c2noc3c2CN(C(=O)C2CCC2)CC3)c1 +Cc1ccc(OCCN2CCCCS2(=O)=O)cc1 +CC(C)(C)Oc1cc(CNC(=O)NCc2ncccc2F)ccn1 +COCCNC(=O)NCCc1ccc(-n2cccn2)cc1 +Cc1ccc(F)c(N2CCN(C(=O)c3cccs3)C(C)C2=O)c1 +O=C(CCC1CCCO1)Nc1ccc(CCN2CCOCC2)cc1 +COc1ccc(Nc2nc(-c3ccc(N)cc3)cs2)cc1OC +Cc1noc(C)c1C(C)NC(=O)N1CCC2CCCCC21 +N#CCCCn1c(-c2cccnc2)nc2ccccc21 +CCC(OC)C(=O)Nc1ccc(-n2cccn2)nc1 +CC1Cc2cc(S(N)(=O)=O)ccc2N1Cc1nc(C2CC2)no1 +CC(NC(=O)Cn1c(=O)[nH]c2ccccc21)c1ccc(F)c(Cl)c1 +CN(C)S(=O)(=O)c1cccc(NC(=O)Cc2ccon2)c1 +Cc1cc(C)c(C(=O)Nc2cccn(Cc3ccc(F)cc3)c2=O)o1 +N#CCC(=O)Nc1sc2c(c1C(=O)NCC1CCCO1)CCCC2 +COc1ccccc1CC(=O)Nc1c(F)c(F)cc(F)c1F +CCN(CC(=O)c1ccccc1OC)CC(F)(F)F +O=C(c1ccco1)N1CCC2(C1)CN(C(=O)c1ccno1)CCC2F +CCOC(C)c1nc(CN2CCN(C(=O)c3ccoc3)CC2)cs1 +COC(=O)CCN(C)C(=O)c1cc(F)c(Cl)cc1Cl +COC(=O)C(c1ccccc1)N1CCCN(CC(F)(F)F)CC1 +CC(C)CSc1nc2ncccc2c(=O)n1CC1CCCO1 +O=C(CCn1cnc2ccccc2c1=O)Nc1nncs1 +CC(=O)NCc1nc2ccccc2n1Cc1ccccc1C +CC(=O)c1c(C)[nH]c(C(=O)CN2CCN(C(=O)C(C)C)CC2)c1C +O=C(Cc1ccc(NC(=O)C2CCCC2)cc1)NC1CC1 +c1ccc(-c2noc(N3CCCC(c4nnc5ccccn45)C3)n2)cc1 +COc1cccc(OCC(=O)OCc2nc3ccccc3[nH]2)c1 +CCCN(C)CC1=C(C(=O)OCC)C(C)NC(=O)N1 +CCC(=O)N1CCc2cc(C(=O)N(CC)c3ccccc3C)ccc21 +CN(CCc1ccc(F)cc1)C(=O)c1cc(Br)c[nH]1 +COc1c(C)cnc(CNC(=O)CCc2ccc(F)c(F)c2)c1C +Cc1ccc(S(=O)(=O)CCNC(=O)OCC(F)(F)F)cc1C +COc1ccccc1C(=O)N1CCN(C(=O)c2cccc(F)c2)CC1 +Cc1nc(-c2ccc(N(C)CCO)cc2)n(CCO)n1 +Cc1cc(C(=O)Nc2ccc3c4c(cccc24)CC3)on1 +COCCN(CCC#N)S(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(OC)c(-n2ccnc2-c2nccn2C(C)C)c1 +Cn1ncnc1CNC(=O)NC1Cc2ccccc2C1 +O=C(c1ccccc1NCCOc1ccccc1F)N1CCCCC1 +O=C(NCc1ccoc1)c1cn(Cc2ccccc2)c2ccccc12 +CCSc1nc2c(cc1C#N)CN(Cc1ccccc1)CC2 +COc1ccccc1N1CCN(CC(C#N)CCC#N)CC1 +COc1ccc2c(c1)OCC(c1nc(COc3ccccc3)no1)C2 +COc1ccc2ccccc2c1CNC(=O)c1cnc2onc(C)c2c1 +C=CCN(C)S(=O)(=O)c1ccc(NC(N)=O)cc1 +Cc1csc(NC(=O)c2ccc(-n3cccn3)cc2)n1 +CCOC(=O)c1[nH]nc2c1CCOc1c(F)cccc1-2 +Cc1nc(C(NC(=O)c2ccc(=O)[nH]c2)c2ccccc2F)no1 +CN(C)C(=O)c1ccc(Cl)c(NCC(=O)NCc2ccccc2)c1 +O=C(Cn1cnnn1)N1CCN(C(=O)c2cc(C3CC3)[nH]n2)CC1 +O=C(CSc1ccc(F)c(F)c1)N1CCCCC1C1OCCO1 +COCCOc1cccc(NC(=O)N(C)C(C)CC#N)c1 +COc1cc2c(cc1OC)CN(C(=O)c1ccc(=O)[nH]c1)CC2 +O=C1Nc2ccccc2C12CC(O)=Nc1c2cnn1-c1ccc(F)cc1 +COC(=O)c1ccc(-c2nc(CN3CCOCC3C)cs2)cc1 +O=c1[nH]c2ccc(S(=O)(=O)NCC3CCC3)cc2[nH]1 +O=C(c1ccnnc1)N1CCC2(C1)C(=O)NCC2c1ccccc1 +c1cc(Cn2ccnc2C2CCCC2)c2cc[nH]c2c1 +C#CCOc1ccc(NC(=O)N2CCC(OCC(C)C)C2)cc1 +CCNC(=O)C1CCN(C(=O)NCc2ccccc2OCC)CC1 +CC1CC(C)CN(C(=O)C2(C)Oc3ccccc3NC2=O)C1 +CCOC(=O)CCNc1ccc(C)c(Br)c1 +COc1cccc2cc(C(=O)NCCc3cccs3)oc12 +OCCn1cc(-c2ccc(Cl)cc2Cl)cn1 +CCOc1ccc2c(c1)cc(C(=O)NCc1cc(CC)no1)n2C +O=S(=O)(NCc1nnc2ccccn12)c1cc(F)c(F)cc1F +O=C(NCCCN1CCc2ccccc21)c1ccc(=O)[nH]c1 +CCOC(=O)C1=C(COC(=O)c2ccc(F)cc2F)NC(=O)NC1 +O=c1[nH]nc(CN2CCN(C3c4ccccc4-c4ccccc43)CC2)[nH]1 +CCc1ccc(S(=O)(=O)NCc2cc(C)oc2C)cc1 +CCc1c(C(=O)N2CCCC(C)C2)cnn1-c1ccc(F)cc1 +CCn1cnnc1CNC(=O)Nc1ccccc1OCC1CC1 +Cc1noc(COC(=O)C2CC2c2ccccc2F)n1 +Cc1nc(NC(=O)CCc2ccc3c(c2)OCO3)sc1C +Cc1c(C)c2ccc(OCC(=O)NCCCO)cc2oc1=O +Cc1nnc(SC(C(N)=O)c2ccccc2)n1C1CCCCC1 +O=C(CSc1nnnn1-c1ccccc1)c1ccc(O)cc1O +Cc1nnnn1-c1cc(NCc2cc(=O)n(C)c(=O)n2C)ccc1F +Cc1ncc(CNC(=O)Nc2ccc(C(C)(C)C)cc2)s1 +Cc1ccc(C(=O)NC(C)c2cnn(C)c2C)s1 +CC(O)(CNC(=O)Cc1noc2ccccc12)c1ccc(F)cc1 +CCN1CCOC(CC(=O)Nc2cccc(Cl)c2C)C1=O +Cc1ccc(C2CC(C(F)F)n3nccc3N2)cc1 +Cc1cccc(CC(=O)N2CCC(Oc3ccc(C)nn3)CC2)c1 +Cc1nc(C2CCN(c3ncccn3)C2)cc(=O)[nH]1 +Cc1nn(-c2n[nH]c(C)c2Br)c(C)c1C +CC(NC(=O)Nc1ccc(N2CCNC(=O)C2)nc1)c1ccccc1 +O=C(NCc1ccc(F)cc1F)C1CC(=O)N(C2CCOCC2)C1 +CCCc1nnsc1C(=O)NCCn1ccnc1-c1ncccn1 +CCCCN1CC2=C(C1=O)C(c1ccc(F)cc1)NC(=O)N2C +OCC1CN(c2ccc(Cl)cc2)C(c2ccccn2)O1 +CCOC(=O)C(O)Cc1nc2c(C)cccc2s1 +O=C(CCC(=O)N1CCCCC1)c1ccc2c(c1)CCCC2 +CNC(=O)CNC(=O)c1ccc2c(c1)-c1ccccc1C2 +CCC1CCC(NC(=O)N2CCN(Cc3ccncc3)CC2)CC1 +CCn1cc(C(=O)NC(C)CN2CCOCC2)c(C)n1 +COc1ccccc1SCc1nc(N)c2ccccc2n1 +CCCn1c2c(=O)[nH]c(=O)n(C)c2n2c(-c3ccccc3)nnc12 +Cc1ncc(CN(C)C(=O)Nc2ccc3c(C)cc(=O)oc3c2)s1 +COc1ccc(C(=O)Nc2ncccc2C)c(O)c1 +CCC1(CC)Oc2ccc(O)cc2N(C(C)C(=O)OC)C1=O +CC(C)NC(=O)C1CCN(c2cc(Cl)ccc2Cl)C1=O +Cc1ncc(Br)c(-c2c(F)cccc2F)n1 +NC(=O)C1CCCN(c2ccc(C(=O)OC3CC4CCC3C4)cc2)C1 +Cc1cc(C)nc(NC(C)C23CC4CC(CC(O)(C4)C2)C3)n1 +Cc1csc(C(C#N)C(=O)CN(C)S(=O)(=O)c2ccccc2)n1 +COc1ccc(-c2c(CO)nnn2-c2ccc(C)cc2C)cc1 +COC(=O)c1[nH]c2ccccc2c1NC(=O)c1ccc(F)cc1 +COc1cc(OC)cc(C(=O)N(C)C(C#N)C(C)C)c1 +CN(C)C(=O)c1ccc(S(=O)(=O)NCCc2cccs2)cc1 +COCCN1CC(C(=O)NCCc2ncccc2C)CCC1=O +Cc1cc(CNC(=O)c2ccc(-n3cncn3)cc2)ccc1F +N#Cc1cccc(C(=O)N2CCC(CC(N)=O)CC2)c1 +COC(=O)C1=C(C(=O)OC)C2OC1c1cc3ccccc3cc12 +COc1ccc(C(O)Cc2ccc3ccccc3n2)cc1 +O=C1Nc2ncccc2C12Cc1ccc(Br)cc1C2 +O=C(CSc1ccncc1)Nc1cccc(N2CCCCCC2)c1 +CCn1ncc(-c2ccc(F)cc2)c(CC#N)c1=O +COc1ccc(F)cc1NC(=O)c1nc2ccccc2s1 +Nc1nc(N2CCOCC2)cc(N2CCCC(CO)(CC3CC3)C2)n1 +C=CCOC1C2CCC1N(C(=O)c1cnc(C)cn1)CCO2 +COc1ccc(-c2nc(C)nc(N3CCCC3)c2N)cc1 +C=CCN1C(=O)CCCC12CCCN(C(=O)c1cncc(C)c1)C2 +Cc1ccccc1SC1CCN(C(=O)c2ccc(CO)cc2)CC1 +Cc1nc(CNC(=O)Nc2cc(F)ccc2OC(C)C)c(C)s1 +CC(C)c1nc(CCN(C)Cc2cccc3nonc23)no1 +CC(C)C(=O)NCCc1ccc(S(N)(=O)=O)s1 +Cc1n[nH]c(SCc2nc(-c3cccc(Cl)c3)no2)n1 +CCCN(CCC)C(=O)CN1C(=O)COc2cccc(N)c21 +COc1ccc(C(=O)N2CC(C)OCC2C)cc1OC +Cc1nc2ccccc2nc1COC(=O)c1n[nH]c(=O)c2ccccc12 +CC(=O)c1ccc(NC(=O)CSc2ccccc2)cc1C +O=C(COc1ccccc1O)NCCNC(=O)c1ccco1 +CCn1c(=O)oc(=O)c2cc(Br)ccc21 +CCCN(CCC)C(=O)c1cnc(N)c(Cl)c1 +Cc1cnc(C(=O)Nc2ccc(NC(=O)C3CC3)cc2)cn1 +Cc1cccc(C(=O)N2CCc3onc(COCC4CC4)c3C2)c1 +CCCc1cc(C(=O)NC(C)c2ccccc2)n(C)n1 +CC(C)CCC(=O)N1CCN(CCn2cccn2)CC1 +Cc1cc(NC(=O)N(C)Cc2ccccc2F)no1 +CC(C)C(C)NC(=O)N1CCN(C(=O)c2ccco2)CC1 +CCC(=O)c1ccc(OCC(O)Cn2nnc3ccccc32)cc1 +Cc1n[nH]c(C)c1Cc1nc(C2(c3ccccc3)CC2)nn1CCO +Cc1ccc(-n2cc(C(=O)N3CCCC3Cn3cccn3)nn2)cc1 +CCC(NC(=O)c1cnn2cc(C)cnc12)c1ccc(OC)cc1 +CCCNC(=O)CCNC(=O)c1scnc1C1CC1 +Cc1cc(C(=O)NCC#Cc2cccc(C(F)(F)F)c2)on1 +Cn1cccc1C(=O)N1CCn2nnc(COc3ccccn3)c2C1 +O=C(COC(=O)C1CC2CCCC(C1)C2=O)c1ccccc1 +Cc1ccc(N)cc1NC(=O)CSc1ccccc1F +COCCNC(=O)Nc1ccc(OC(C)C)cc1F +CSc1ccccc1C(=O)Nc1ccc(NC(C)=O)cc1 +Cc1ccc(C)c(S(=O)(=O)N2CCC(=O)Nc3ccccc32)c1 +CC(C)CC(=O)Nc1ccc(C(=O)CSc2nccn2C)cc1 +O=S(=O)(NCc1ccsc1)c1ccc(OC(F)(F)F)cc1 +Nc1ccc(Cn2c(C3CC3)nc3cc(F)ccc32)cn1 +O=C(C1COCCO1)N1CCN(c2cccc(Cl)c2)CC1 +CCCNc1nnc(S(=O)(=O)Cc2ccn(C)n2)s1 +CCOc1ccc(N2CC(C(=O)N3CCOCC3)CC2=O)cc1 +COc1ccc(F)cc1NC(=O)NCc1ccccn1 +O=C(Nc1ccc(C(=O)N2CCCCC2)cc1)c1ccccc1F +CCCOc1cc(C)ccc1NC(=O)c1ccc(-n2ccnn2)cc1 +O=C(CCOc1ccccc1)NC1CCSc2c(F)cccc21 +COc1ccc(CNc2cc(-c3ccccc3)nc3ncnn23)cc1 +COc1cccc(C(=O)N2CCCN(c3nc(C)cs3)CC2)c1O +Cc1ccccc1C1CC(O)C(O)C1NS(=O)(=O)c1ccccc1 +O=S(=O)(c1cncc(F)c1)N1CCC2(CCCCC2)C1 +O=C(NCCCc1cccc(F)c1)N1CCC2(C1)OCCO2 +CCOC(=O)c1c(C)[nH]c(C(=O)Nc2ccncc2)c1C +CC(C)(C)n1nnnc1SCC(=O)NC1CCOCC1 +Cc1ncc(C(C)NCC2(c3cccc(F)c3)CC2)s1 +Cc1ccc(OC(C)CNCc2cncnc2)cc1 +CCc1ccc(OC)c(CCNC(=O)CCC#N)c1 +CNc1ncc(C(=O)Nc2c(C)n[nH]c2C)cc1Cl +CC(C)CC(=O)NCc1noc(Cc2ccccc2)n1 +Nc1ccc(S(=O)(=O)NC2CCCCCC2)c(Br)c1 +Cc1cccc2c(NC(=O)c3cccs3)ccnc12 +CC(C)(C(=O)Nn1cnc2ccccc21)c1ccccc1 +CNC(=O)CN(C)C(=O)c1nn(-c2ccccc2C)c2c1CCC2 +CC(C)CC(O)C(=O)N1CCC2(CC1)Nc1ccccc1NC2=O +Cc1ccc(Cl)cc1NC(=O)c1cc2ncccn2n1 +Cc1cccc(NC(=O)NC2CCCc3sc(C)nc32)c1 +CCOC(=O)C(O)Cc1nc2cccnc2s1 +CCC(O)CN(Cc1ccccc1)C(=O)NCc1ncn(C)n1 +CCNc1ccc(S(=O)(=O)N2CCCC2)cn1 +O=C(NCCc1csc(-c2ccncc2)n1)c1ccccc1Cl +CCOC(=O)COC(=O)c1cccc2ccccc12 +O=c1c2ccoc2ccn1Cc1ccc(OC(F)F)cc1 +O=c1nc(SCc2ccccc2Cl)c2c(n1CCO)CCC2 +CCCC1CN(C(=O)c2ccc(C#N)cc2)CCO1 +Cn1cnc(-c2nc(C(=O)NCCc3ccccn3)c3ccccn23)c1 +CC(C)c1nn(C)c2sc(C(=O)N3CCC(O)C3)cc12 +CC(c1ccco1)N(C(=O)NC1CCN(C)C1=O)C1CC1 +O=C(Cn1c(=O)oc2ccccc21)N(Cc1ccsc1)C1CC1 +CCC(C(=O)NC1CCN(C(=O)C(C)C)CC1)c1ccccc1 +Cc1ccccc1CN(C)C(=O)Nc1cnn(-c2ccccc2F)c1 +COc1cccc(NC(=O)NCCc2ccoc2)c1OC +CCc1ccc(C(C)NC(=O)CN2CCN(CCO)CC2)cc1 +CC(O)CN1CCN(C(=O)CCOc2ccccc2Cl)CC1 +O=C(Nc1ccc(Cc2ccncc2)cc1)c1ccncc1 +CCc1noc(CNC(=O)CCc2scnc2C)n1 +Cc1nc(NC(=O)CCc2ccco2)sc1-c1ccccn1 +CC(C)CNC(=O)Cc1csc(-c2ncccn2)n1 +COc1cccc(NC(=O)NCC#Cc2ccccc2N(C)C)c1 +Cn1c(=O)c2ccccc2n(CC(=O)Nc2ccccc2F)c1=O +N#Cc1ccc(COC(=O)Cc2cc3ccccc3[nH]c2=O)cc1 +CCOCCN(CC)C(=O)c1cnc(C2CCCO2)s1 +Cc1nn(CC(C)C)c(C)c1CCC(=O)NCc1ccco1 +Cc1ccc(C(=O)Nc2ccc(N3CCCC3)cn2)cc1C +CC(NC(=O)C1CCCCC1)C(=O)NCc1ccoc1 +O=c1[nH]c(-c2ccco2)ccc1-c1nc(-c2ccncc2)no1 +COc1cccc(C(O)CNCc2coc(-c3ccc(C)cc3)n2)c1 +CCCC1CN(C(=O)CCSc2nnnn2C)CCO1 +O=C(NCC1CCCO1)c1nnc(Cc2cccc(Cl)c2)o1 +Cc1nc(C)c(C(=O)Nc2cccc(Br)c2)o1 +CN(CCc1ccccn1)c1ncccc1CNC(=O)c1ccccn1 +CN(C)C(=O)COC(=O)c1cccc(NC(=O)c2cccs2)c1 +Nc1oc2c(c1C(=O)c1ccc(F)c(F)c1F)CCC2 +Cc1nnc(CNC(C2CCCC2)C(F)(F)F)o1 +COc1ccnc(NC(CC(N)=O)C2CCCCC2)n1 +O=C1Nc2cccc(Br)c2OC1c1ccccc1 +C=CCn1c(N)nnc1SCc1csc(C2CCCCC2)n1 +Nc1ccccc1NC(=O)c1ccc(OC(F)F)cc1 +Cc1ccc(C(O)CNC(=O)COc2ccccc2F)o1 +O=C(NCc1cccnc1)Nc1cccc(Br)c1 +O=C(NCCCN1CCCC1=O)c1cccc(Nc2ncccn2)c1 +CCNC(=O)c1cccc(NC(=O)Nc2ccccc2)c1 +Cc1ccc(S(=O)(=O)N2CCCC2C(=O)Nc2cc[nH]n2)cc1 +CCn1c(COc2ccc3c(c2)CCCC3)nnc1SCC(N)=O +CNc1snc(C)c1C(=O)NCCCN1CCc2ccccc21 +CCOC(=O)c1cnc2nc(SCC)nn2c1C=CN(C)C +CCC(=O)N1CCc2c(C(=O)NCc3cccs3)cccc21 +CC(C)c1noc(CCC(=O)Nc2cccc(-n3cnnn3)c2)n1 +COc1c(CNCc2ccc(-n3cccn3)nc2)c(C)nn1C +CC(C)C(=O)N1CCN(S(=O)(=O)C2=Cc3ccccc3CC2)CC1 +Cc1nnc(NC(=O)c2nn(C(C)C)c(=O)c3ccccc23)s1 +Cc1cc2occ(CC(=O)NCc3cscn3)c2cc1C(C)C +CC1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +CCC1(C)C(=O)NCCN1C(=O)Cc1cn2ccsc2n1 +Cn1ncc(C(=O)Nc2cc(F)cc(F)c2)c1-n1cccc1 +O=C(Nc1c[nH]ccc1=O)c1ccc(C(F)(F)F)cc1 +COC1CCCN(C(=O)Cc2cccc(OCC#N)c2)C1 +CC1(C)CN(C(=O)Nc2ccc(Br)cc2)CCO1 +Cc1nc2ccc(C(=O)N3CCOC(c4ccccc4)C3)cc2s1 +Cc1cccc(OCC(C)NC(=O)CCc2c(C)noc2C)c1 +C#CCNC(=O)C(NS(=O)(=O)c1ccc(C)cc1)C(C)C +CCOC(=O)c1c(C)oc(NC(=O)Nc2ccccc2F)c1C(N)=O +NC(=O)C1CCCN(C(=O)c2cccc(Cl)c2)C1 +CC(C)COc1ccccc1NC(=O)NCCc1ccccn1 +COc1cc(CNc2cccc(Cl)c2)ccc1OCC(N)=O +CCc1ccc(C(=O)N(C)CCC(=O)OC)s1 +Cc1cccc2nc(C(=O)N3CCCCCC3c3ccco3)c(F)n12 +Cc1c(C(=O)NCCCO)nnn1Cc1ccccc1 +OCc1ccc(Oc2ncccc2C(F)(F)F)cc1 +CCC(=O)N1CCc2cc(C(=O)N(C)Cc3ccc(O)cc3)ccc21 +CSc1ncccc1C(=O)NCC(=O)Nc1ccc(F)c(F)c1 +Cc1ccc(NCC(=O)N2CCCCC2)cc1C(=O)NC(C)C +N#Cc1cc(C#N)c(SCc2ccn(-c3ccccc3)n2)nc1N +Brc1ccc2c(c1)C(C1CCC1)NCC2 +O=C(NC1CCCN(Cc2ccccc2)C1=O)N1CCC(CO)CC1 +Cn1cc(C(=O)NCCOc2ccc(F)c(F)c2)c(C(C)(C)C)n1 +Cc1nc(NCCCN2CCOCC2)c2nc(C)oc2n1 +CC(C)(C)c1nc2cc(N)ccc2n1Cc1cccc(N)c1 +CN(C)c1ncc(-c2cc(C(=O)N3CCCC3)n(C)c2)cn1 +COc1ccccc1CNS(=O)(=O)c1cccc2nonc12 +CCCCNC(=O)N(C)Cc1ccc(C(=O)NC)cc1 +CCOc1ccc(NC(=O)NCc2nnc3ccccn23)cc1F +Nc1cnn(CCCOc2cccc(Br)c2)c1 +CCN(CC)C(=O)CCCNC(=O)c1cnc2ccc(C)cn12 +CC1CCN(C(=O)c2cccc(OC(C)C)c2)CC1 +O=S(=O)(c1ccc(F)c(F)c1F)N1CCc2ccccc2C1 +N#Cc1ccc(CNc2ccc(S(N)(=O)=O)cc2)cc1 +COC(=O)C(C)(C)NC(=O)c1c[nH]c2cccc(F)c12 +CC(C)C(NS(=O)(=O)c1cccc(Cl)c1)C(=O)NC1CC1 +CN(Cc1ccccc1)C(=O)CNc1ccc(F)c(Cl)c1 +O=C(Nc1ccc2c(c1)OC(F)(F)O2)OCC(F)(F)F +Cc1nnc(SC(C)C(=O)Nc2ccc(F)c(F)c2)n1N +O=C(COc1ccc(Cl)cc1-n1cnnc1)Nc1cccnc1 +NC(=O)C(Sc1ncnc2ccccc12)c1ccc(F)cc1 +COc1cc(C)c(C(O)Cn2cc(N)cn2)cc1Cl +CC1CCC(C(=O)NCC2CCC(C)(C)CC2)O1 +Cc1ccc2nc(C(=O)NCc3nnnn3-c3ccccc3)cn2c1 +Cc1ccnc2nc(C(=O)NC(COCC(C)C)c3ccco3)nn12 +COC(=O)CCn1c(=O)[nH]c2cc3c(cc21)OCCO3 +Cc1csc(C2CCCN(C(=O)c3nccnc3N)C2)n1 +CCc1ccc(-c2ccc(=O)n(CC(=O)N3CCC(C)CC3)n2)cc1 +CC(COc1ccccc1C(F)(F)F)NC(=O)NCC1CC1 +COc1ccccc1NC(=O)c1nc2cc(Cl)ccn2c1C +CC(C)C(=O)Nc1nc(CC(=O)N(C)CCc2ccccn2)cs1 +COc1ccc2nc(N3CCC(n4cncn4)CC3)c(C)cc2c1 +Cn1nnc2cc(C(=O)N(CCO)c3ccccc3)ccc21 +Cc1n[nH]c(C2CN(C(=O)c3cc(Cl)c[nH]3)CCO2)n1 +CCc1ccc(-n2nc(CO)c(C(=O)NC(CC)CO)n2)cc1 +CC(C)C(NC(=O)c1ccco1)C(=O)N1CCc2cc(F)ccc2C1 +CCCC1CN(C(=O)c2cc3ccccc3oc2=O)CCO1 +CC(=O)N1CCCC1c1cccc(Cc2ccc(F)cc2)n1 +COc1ccccc1-c1nn(C)cc1C(=O)NCc1noc(C)n1 +CCS(=O)(=O)N1CCCC1C(=O)c1ccc(Cl)cc1 +COC(=O)CC(C)C(=O)NCC1CN2CCCCC2CO1 +COc1ccc(NC(C)C(=O)NCc2ccc(C)cc2)cn1 +N#Cc1ccc(OCCNC(=O)Cc2c(F)cccc2F)cc1 +O=C(N1CCOCC1)N1CCN(S(=O)(=O)c2ccccc2)C1 +CCNS(=O)(=O)c1cccc(C(=O)Nc2ccccc2C(C)C)c1 +CCc1ccccc1NC(=O)Nc1cc(F)c2[nH]c(=O)ccc2c1 +COC(=O)c1cc(-c2ccc3c(c2)OCO3)nc2onc(C)c12 +Cc1nc2ccccc2n1S(=O)(=O)N1CCOCC1 +O=C(Nc1ccncc1)C1CCN(c2ccc(-n3cccn3)nn2)CC1 +CC(Cc1ccncc1)NC(=O)CC12CC3CC(CC(C3)C1)C2 +CCOC(=O)C(C)(C)NCc1nnnn1C1CC1 +COC(=O)c1ccc(OC(=O)c2ccc(C#N)c(C)n2)cc1 +NC(=O)c1sc2nc(-c3ccco3)cc(C(F)(F)F)c2c1N +CC(c1ccccc1Cl)N(C)C(=O)Cn1c(=O)[nH]c2ccccc21 +COc1cccc(CN(C)C(=O)c2ccc(-c3ccccc3)[nH]c2=O)c1 +CCCC1CN(C(=O)c2cccc(NC(=O)NC(C)C)c2)CCO1 +COCC1(C(=O)NCCc2ccccc2F)CC1 +COc1cc(OC)cc(OS(=O)(=O)c2c(C)noc2C)c1 +COC(=O)c1ccc(NC(=O)N2CCOCC2C2CC2)cc1F +CN1CC(C(=O)Nc2ccc(C(=O)N3CCCCCC3)cc2)CC1=O +Cc1nc(CN(C)C(=O)NC2CCCCNC2=O)cs1 +COC(C)(CNC(=O)c1cccc(N(C)C)c1)c1ccccc1F +O=C(NCCCN1CCOCC1)NC1CCc2cc(Cl)ccc21 +COc1cc(C)c(C(=O)N2CCC(NC(C)=O)CC2)cc1OC +Cc1c(Br)cc2c(c1C)OCC(N1CCCC1)C2=O +CC(C)CNC(=O)N(C)CC(=O)Nc1cccc(F)c1 +Cc1cnc(N)nc1NCC1(N2CCOCC2)CCCCCC1 +Cc1nn(C)c(C)c1S(=O)(=O)NC1CCCCNC1=O +Cn1c(=O)ccn(CC(=O)NC2CCCCC2)c1=O +Cc1ccc(CNCC(O)c2ccc(F)c(F)c2)o1 +CNC(=O)c1cc2c(C)nn(Cc3ccc(F)cc3)c2s1 +CCc1cc(NCc2cccnc2)n2nccc2n1 +CN(Cc1cnc(-c2ccsc2)s1)CC1CCCCO1 +CC(=O)Nc1ccc(OC(=O)Cn2nc3ccccn3c2=O)cc1 +CCNC(=O)C(C)Nc1ncnc2sc(-c3ccccc3)c(C)c12 +Cc1cccc(CNC(Cc2ccccc2)C(=O)N(C)C)c1 +Cn1c(C(=O)NCCNC(=O)C(C)(C)C)cc2ccccc21 +N#CCCN(Cc1ccc(C#N)cc1)Cc1cccnc1 +CCc1ccc(CNC(=O)N2CCN(CCOC)C(=O)C2)s1 +O=C(Nc1cnn(-c2ccccc2F)c1)c1cccnc1 +CC(C)N(C)C(=O)Cc1ccc(-n2cccn2)cc1 +Nc1ccc(C(Cc2cccnc2)C(=O)N2CCCC2)cc1 +COC(=O)c1nnn(Cc2ccc(Cl)cc2)c1C +CCCCCOC(=O)C1C(C)=NC2(O)c3ccccc3C(=O)C12O +CC(C)c1nc2cc(C(=O)N3CCOCC3)ccc2o1 +COc1cccc(C(=O)Nc2nnc(-c3ccncc3)s2)c1OC +COC(=O)c1cc(OC)ccc1NC(=O)c1c[nH]c2cccc(F)c12 +CCOc1cc(C(=O)Nc2ccc(F)cc2)ccc1OC +CCn1c(C(C)NC(=O)c2nccnc2N)nc2ccccc21 +Cc1ccc(OCCNC(=O)CNC(=O)c2ccc(C)cc2)cc1 +CC1=C(C(=O)OC(C)C)C(c2ccccc2F)NC(=O)N1 +CC(O)c1cccc(OCCOc2ccc3ncccc3c2)c1 +O=C(NCCn1cccn1)c1cc(Cn2ccc3ccccc32)[nH]n1 +CCn1cc(NC(=O)NCc2ccco2)c2ccccc21 +Cc1ccc(NC(=O)c2cnc3n(c2=O)CCS3)cc1C +Nc1nc(SCc2nnnn2-c2ccccc2)n[nH]1 +CC(C)NC(=O)c1ccccc1NC(=O)c1csnn1 +CC(C)=CC1C(C(=O)N2CCCC2c2cnn(C)c2)C1(C)C +COCCCNC(=O)Cn1c(=O)n(C)c(=O)c2sccc21 +O=S(=O)(NCc1ccc(Cl)cc1)c1ccc(F)cc1F +C#Cc1cccc(NC(=O)c2ccc(C)c(OC)c2)c1 +COC(=O)CSc1nnc(C(C)Oc2cccc(Cl)c2)n1C +O=C(NCc1cc(-c2ccco2)on1)c1cccc(Br)c1 +CCCn1nc(CO)cc1-c1ccc(Cl)cc1 +O=C(NCCO)c1ccc(COc2ccc(Br)cc2)o1 +CCC(C)C(=O)NC1CCOc2ccc(C(O)C(C)C)cc21 +Cc1csc(NC(=O)CSc2nnc(-c3cc(C)on3)o2)n1 +O=C(OC(c1ccccc1)c1ccccn1)c1cccnc1 +Cn1cnnc1CCC(=O)NCCc1ccc(Cl)cc1Cl +Cc1noc(C)c1CC(=O)NCC1(c2ccc(F)cc2F)CC1 +COc1ccc(NC(C)=O)cc1NC(=O)CCc1ccccc1Cl +CNS(=O)(=O)C1CCCN(c2ncc(Cl)cn2)C1 +Cc1nn(C)c(C)c1CC(=O)NCC(c1ccccc1)C(C)C +CCN(C(c1cccnc1)c1ccc2c(c1)CCC2)S(=O)(=O)CC +Nc1ccc2[nH]c3nnc(-c4ccccc4C(F)(F)F)n3c2c1 +Cc1cccc(OCCCC(=O)Nc2ccccc2-n2cnnn2)c1 +COC(=O)Nc1ccc(NC(=O)NCC2(C)CCCC2)cc1 +COC(=O)C(Cc1ccc(F)cc1)NC(=O)c1c(C)nn(C)c1C +CN(CC(=O)NC(C)(C)C)C(=O)c1cc(Cl)cc(Cl)c1 +CCC(C(=O)Nc1sc2c(c1C(N)=O)CCC2)c1ccccc1 +COC(C)(CNC(=O)CCC(F)(F)F)c1ccccc1F +Cc1cc(CN(C)C(=O)c2ccccc2OC(F)F)no1 +Cc1cc(C)c(NC(=O)Cc2ccc(F)cc2)c(C)n1 +COc1ccc(F)c(NC(=O)N(C)C(C)CC#N)c1 +O=C(CNC(=O)C1COc2ccccc21)OCc1ccccc1 +CC(=O)N1CCN(c2nc3c(cnn3C(C)(C)C)c(=O)[nH]2)CC1 +CCOc1ccccc1N1CC(C(=O)NCc2ccccc2)CC1=O +CN(C)S(=O)(=O)c1ccc(C(=O)Nc2ccn(C)n2)cc1 +Cc1ncsc1C(=O)Oc1cccc(NC(=O)C2CC2)c1 +Cc1cc(C)cc(NC(=O)COc2cccc3ccc(=O)[nH]c23)c1 +COc1ccc(CNC(=O)COC(=O)c2cc(C)oc2C)cc1 +COc1cc2c(c(OC)c1O)C(CNC(C)=O)NCC2 +Cc1cc(=O)c2c(O)c3cc(C(C)(C)O)oc3cc2o1 +CC1CN(C2CCN(c3c(C#N)c(=O)n(C)c(=O)n3C)CC2)CCO1 +CCc1cc2c(=O)n(C(C)C(=O)c3ccccc3)cnc2s1 +CCOCC1CN(S(=O)(=O)N(C)C)Cc2nnn(CC3CC3)c21 +Cc1ccc(NC(=O)COC(=O)c2c(C)oc(C)c2C)c(Cl)c1 +Cc1ccccc1-n1nnnc1SCc1cn2ccccc2c1C#N +CCC(CC)N(C)C(=O)c1ccc(-n2nc(C)cc2C)cc1 +Cc1cccc(N2CCN(C(=O)c3ccc4cc[nH]c4c3)CC2)c1C +CC(C)COC1CCN(C(=O)NCc2ccccc2Cl)CC1 +CCOc1ccc2cc3c(N)c(C(=O)OC)sc3nc2c1 +CCCS(=O)(=O)c1nsc(C(=O)NC2CC2)c1N +Cc1ccccc1OC(=O)C1CCCN1C(=O)Cc1cccs1 +CC(=O)Nc1cccc(NC(=O)c2cc(F)ccc2F)c1 +Cc1cc(O)ccc1NC(=O)c1cn(C)c2cccc(N)c2c1=O +Cc1cc(C(=O)Nc2ccc3c(c2)OCO3)ccc1N +COc1ccccc1NCC(=O)NCCc1ccc(F)cc1 +COC(C)(C)c1noc(Cc2csc(-c3ccccn3)n2)n1 +CC(=O)Nc1ccc(NC(=O)CCn2nc(C)cc2C)cc1 +Cn1cc(C(=O)Nc2nc3c(s2)CCC3)c2ccccc2c1=O +COCc1ccccc1C(=O)OCC1CC(=O)N(C2CC2)C1 +COC(=O)CCCN1CCNc2cc(F)ccc21 +COC(=O)C(NC(=O)C1CC1c1ccc(F)cc1)c1ccccc1 +Cc1cc(C(C)NC(=O)c2sc(C)nc2C)c(C)s1 +CCOC(=O)c1cccc(NC(=O)C2COc3ccccc3O2)c1 +Cc1ccncc1NC(=O)NCc1nnc2ccccn12 +COC(=O)c1ccccc1NC(=O)COC(=O)c1occc1C +CC1CN(c2oc(-c3ccccc3)nc2C#N)CC(C)O1 +Cc1ccc(-c2n[nH]c(SCCC(N)=O)n2)cc1 +CC(C(=O)N1CCN(C)CC1c1ccccc1)n1cnc2ccccc21 +Cn1cc2c(N3CCCC3)nc(C(=O)NC3CCCCC3)nc2n1 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+Nc1c(Nc2ccc(F)cc2F)ncnc1N1CCOCC1 +COCCN1CC(C(=O)OC(C)c2ccc3c(c2)OCCO3)CC1=O +CCOc1ccccc1C(=O)Nc1cc(=O)n(C)c(=O)n1C +COc1ccc(C(=O)NCc2ccncc2)cc1F +CCCCC(=O)Nc1cccc(-c2nn3c(C)nnc3s2)c1 +CS(=O)(=O)NCCNC(=O)c1sc2ccccc2c1Cl +COc1cccc(C(O)Cc2ccccc2OC)c1 +Cc1cc(C(=O)NC2CCc3nnc(C(C)C)n3C2)no1 +Cc1ccccc1C(=O)OCc1nnc(-c2ccccc2)o1 +CCc1c(C(=O)NCC2(C(N)=O)CCOCC2)cnn1C(C)(C)C +Cc1ccc(C(=O)N2CCCCC2C(C)C)cc1F +Cc1ccc(CN2CCN(Cc3nccn3C(F)F)CC2)s1 +COCCCC1CCCN(C(=O)c2ccc(O)c(C)c2)C1 +CCOc1cc2c(cc1CNC(=O)c1cccn1C)OC(C)C2 +CCCCN(C)S(=O)(=O)c1ccc2c(c1)CC(C)N2C(C)=O +CCCN(C)C(=O)Nc1cccc(-c2nnc3n2CCC3)c1 +CCn1nc(NC(=O)c2ccncc2)c2cc3ccc(C)cc3nc21 +OCc1c(-c2cccnc2)nc2sc(C3CCC3)nn12 +COCCCC(C)C(=O)N(C)c1cccc(F)c1 +CC1CCC(C(N)=O)CN1C(=O)Cc1cccc(O)c1 +OCc1ccc(Oc2ccc(Br)cc2)o1 +Oc1ccc2c(c1C(F)(F)F)C(CC1CC1)NCC2 +O=S(=O)(Cc1ccccc1)N1CCN(CC2CC3C=CC2C3)CC1 +C=CCn1c(SCc2csc(C)n2)nnc1-c1ccco1 +Cc1csc(NC(=O)c2cnc3onc(C)c3c2)n1 +CCOc1ccc(OC(=O)c2ccc(C)nc2)cc1 +C#CCOC(=O)COc1ccc(C=CC)cc1OC 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+CCCN(Cc1cc2cc(C)ccc2[nH]c1=O)C(=O)c1ccncc1 +CC(C)(CO)N(CCO)C(=O)CCc1ccccc1 +O=C(NCC1(O)CCOc2ccccc21)c1ccoc1 +COc1ccc(OC)c(Nc2ncnc(NC(C)(C)C)c2N)c1 +CCOc1c(Cl)cc2c(c1OC)C(C)NCC2 +CC(=O)c1cnn2c(-c3ccc(F)cc3)ccnc12 +Cc1nccc(CNC(C)c2ccc(Cl)cc2)n1 +CC(C1CCN(C(=O)CCc2ccccc2F)CC1)N1CCOCC1 +Cc1noc(NC(=O)c2ccc(Oc3ccccc3)cc2)n1 +CC(C)N(C)C(=O)C1CCN(C(=O)Nc2ccnn2C(C)C)CC1 +CCOc1ccccc1-n1c(C2CC(=O)N(C)C2)n[nH]c1=O +N#Cc1ccc(CNS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)cc1 +CCc1nc2n(n1)CCCC2NC(=O)c1n[nH]c2ccc(C)cc12 +CC(NC(=O)COC(=O)c1nn(C)cc1Cl)c1ccccc1 +CN(CC1Cc2ccccc2CN1C)C(=O)CCc1ccc(O)cc1 +COCCN(CCC#N)c1ccc(C(C)=O)cc1Br +COC(=O)CNC(=O)c1cn(Cc2ccccc2)nn1 +CC(C)C(NC(=O)NCCc1ncnn1C)c1ccccc1Cl +COc1ccccc1NC(=O)CCc1ccsc1 +COCCC(C)C(=O)Nc1cnn(-c2ccccc2F)c1 +CCc1ccccc1NS(=O)(=O)c1ccc(OC)c(NC(C)=O)c1 +Cc1noc(-c2cccs2)c1C(=O)NCc1ccccc1Cl +CC(C)(C)c1noc(CCCC(=O)NCc2ccccc2)n1 +Cn1ccc2c(=O)[nH]cc(C(=O)NCCC(=O)NC3CCCCC3)c21 +Cc1nc(C2CCN(S(=O)(=O)c3cncc(Cl)c3)CC2)no1 +CN(Cc1ccco1)C(=O)c1ccc(-n2cccn2)cc1 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+c1ccc(-n2cccn2)c(NCc2nc(-c3ccsc3)no2)c1 +COc1cccc(NCC(=O)Nc2cccc(NC(=O)C(C)C)c2)c1 +Cc1ncc(CN(C)C(=O)NCc2cnn(C)c2)s1 +CCOC(=O)CN(CC)C(=O)Cc1ccc(F)cc1 +Cc1cc(C)c2cc(C(=O)OCc3c(C)noc3C)[nH]c2c1 +CC(C)N1CC(C(=O)NCc2ncn(C)n2)CC1=O +CC(=O)NC(C(=O)N1CCN(CC=Cc2ccccc2)CC1)C(C)C +COCCNS(=O)(=O)c1ccc2c(c1)OCCO2 +CC(C)(C)OC(=O)N1CCCC1C(=O)N1CCOC(C)(C)C1 +Cc1ccc2ncc(C(=O)N3CCC(OCc4ccccc4)CC3)n2c1 +COc1cc(OC)c(NC(=O)c2ccnn2C)cc1Br +O=c1[nH]c(Cn2cc(CO)nn2)nc2ccsc12 +CCCCc1cc(NC(=O)c2scnc2C)[nH]n1 +O=C(NCc1ccncc1)Nc1nnc(CC2CCCC2)s1 +Cc1ccc(C(C)C)cc1OCC(=O)N(C)CC(=O)N(C)C +CCOc1cc(NC(=O)N2CCCC2)ccc1OC +CC(=O)N1CCN2C(=O)N(Cc3ccc(F)cc3)CC2C1 +CCCOC(=O)CSc1nnc(-c2ccncc2)n1N +Nc1c(-c2nc(-c3ccncc3)no2)nnn1-c1ccc(F)cc1 +Nc1c(-c2ccncc2)noc1C(=O)Nc1ncccn1 +Cc1cccc(C(=O)OCc2nc(-c3cccc(Cl)c3)no2)n1 +CCNC(=O)c1ccc(-c2ccc(OCC)cc2)nc1N +CC1CCOC1C(=O)Nc1cc(Br)ccc1O +COc1ccccc1CNC(=O)NCC(=O)Nc1ccccc1 +CN(CC(=O)NC1CC1)C(=O)CNc1ccc(F)c(F)c1F +CCCCOC(=O)CCn1cnc2c(cnn2C)c1=O +COc1cccc(C(=O)N2CCc3ccc(N)cc3C2)c1 +Cc1ccc(-c2n[nH]cc2CNCC(O)c2ccc(F)cc2F)o1 +Cc1noc(C)c1C(C)NC(=O)CCNC(=O)Cc1ccccc1 +CCCN(Cc1ccccc1)C(=O)Nc1cc(C)nn1C +O=C(NCc1cc(Cl)ccc1F)c1cncnc1 +CC(C)c1ccc(C#N)c(N2CC(NC(=O)CCO)C(C(C)C)C2)n1 +CC1CCCC(CO)(NS(=O)(=O)C2CCCCC2)C1 +CC(Sc1ncc2ccccn12)C(=O)NCc1cccs1 +CC(C)C(=O)NCCNC(=O)NC1CC1c1cccc(Cl)c1 +NC(=O)CSc1nnc(-c2ccccc2Cl)o1 +NC(=O)C1Cc2ccccc2N1C(=O)c1cc2ccccc2o1 +CC(=O)Nc1ccc(O)c(C(=O)Nc2ccc(C(C)=O)c(C)c2)c1 +CC(=O)c1c[nH]c(C(=O)OCCOc2cccc(Cl)c2)c1 +CCC(O)CN1CCN(C(=O)CCc2nc3ccccc3s2)CC1 +Cn1nnc2c(N3CC(C(=O)N4CCCC4)C3)ncnc21 +COC(=O)C1CCCCCC1NC(=O)c1cc2cc(F)ccc2[nH]1 +Cc1noc(C2CN(C(=O)c3cccc4ccccc34)C2)n1 +COC(=O)c1sccc1NS(=O)(=O)c1ccc(Cl)cc1F +CCCCNC(=O)C1Cc2ccccc2CN1C(C)=O +C#CCN1CCC(C(=O)N2CCN(C(=O)N(C)C)CC2)CC1 +CN(Cc1cnn(C)c1)C(=O)NCCNC(=O)CC1CCCCC1 +CCNC(=O)C(C)NC(=O)c1csc(COc2ccc(C)cc2)n1 +Cc1ccc(OC2CCN(C(=O)COc3cccnc3)CC2)cn1 +CC1Cc2ccccc2N1C(=O)CCc1c[nH]c2ccccc12 +O=C(COC(=O)c1ccccc1-n1cnnn1)c1ccc(F)c(F)c1 +COc1ccc(CC(=O)N2CCOc3ccc(N)cc32)cc1 +CC1(C)Cc2c(sc3ncn4nc(O)nc4c23)CO1 +CC(C)C(=O)N1CCC(C(=O)N=c2sccn2C)CC1 +CCN1CC(NC(=O)c2sc3cccc(F)c3c2Cl)CC1=O +Cc1ccc(CCC(=O)Nc2cc(C)on2)c(C)c1 +O=C(COC(=O)Cc1c(Cl)cccc1Cl)NCC(F)(F)F +Cc1nccn1-c1ccc(C(C)NC(=O)NC(CCO)C(C)C)cc1 +Cc1cc(=O)[nH]c(C2(C)CCCN2C(=O)Cn2cccn2)n1 +O=C(CCC(=O)c1cccs1)Nc1nc2ccccc2s1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(F)c(Cl)c2)cc1 +COc1ccc(C(C)=O)cc1S(=O)(=O)N(C)C +Cc1nn(-c2ccc(F)cc2F)c(C)c1CNCCc1cscn1 +CCn1cc(C(=O)N2CCCCC2c2nc(C)cs2)cn1 +N#Cc1ccccc1OCc1ccc(C(=O)Nc2ccccc2O)o1 +N#Cc1ccc(NCCNC(=O)C2CC3CCC2C3)nc1 +COc1ccc(C(=O)N2CCCCCC2c2noc(C)n2)cn1 +CC(OC(=O)CSc1ncn[nH]1)c1cc(F)ccc1F +Cc1cc(C)c(NC(=O)NCc2cc(C)sc2C)c(C)c1 +COCCNC(=O)CN1CCN(C(=O)c2ccc(C#N)cc2)CC1 +CC1CCCCC1NC(=O)CN(C)S(=O)(=O)c1ccc(F)cc1 +CCc1ccc(C(C)(C)CNC(=O)NCc2ncn(C)n2)cc1 +CC(C)(C)c1cnc(C(=O)NCCc2nnc3n2CCCCC3)o1 +Cc1ncnc(C)c1C1NCCc2cc3c(cc21)OCCO3 +CC(C)NC(=O)Cn1ccc2cc(Cl)ccc21 +CC(C(=O)NCc1ccccc1Cl)N(C)CCC#N +Cc1ccc(CN2CCN(c3ccc4nnc(C)n4n3)CC2)s1 +CCC(=O)Nc1cccc(C(=O)N2CCc3sccc3C2)c1C +Cc1cc(NC(=O)CCCC(=O)c2ccc(F)cc2)ccc1C(N)=O +CCOc1ccc(CCC(=O)Nc2ccccc2)cc1OC +CC(=O)Oc1cccc(C(=O)NC(C)c2ccccc2)c1 +COc1ccc2ccccc2c1-c1cc(Cn2nc(C)ccc2=O)on1 +O=C(CCS(=O)(=O)c1ccc(F)cc1)Nc1cccc(F)c1 +CNc1cc(OCC(C)C)nc(C2CCCO2)n1 +CCOC(=O)C1CCCN(c2ncc(Br)cn2)C1 +CC(C)(C)NC(=O)CNC(=O)N1CCc2sccc2C1 +CN(Cc1nc(-c2ccccn2)no1)C(=O)c1n[nH]c2c1CCC2 +O=C(CN1CCCC1=O)Nc1cccc2ccccc12 +C=CCOc1cccc(NC(=O)N2CCCC(CO)C2)c1 +CCOCCCNC(=O)C1=C2C(=O)N=CN=C2OC1C +CCn1c(SCC(C#N)CCC#N)nnc1-c1cccc(Cl)c1 +CCOC(=O)CCC(C)NC(=O)NC1CCCC1C +CCOC(=O)c1noc2nc(C)nc(Nc3ccc(OCC)cc3)c12 +COc1ccc(Nc2nnc(SCC3CCOCO3)s2)cc1 +COc1ccc2[nH]cc(C(=O)NCc3ccc(F)cc3)c(=O)c2c1 +COC(=O)c1ccc(NC(=O)Cc2ccc(-n3cccc3)cc2)cc1 +CC(C)CCC(=O)Oc1ccc(-n2cnnn2)cc1 +Cc1nn(C)c(C)c1CCC(=O)NC(C)c1csc(C(C)C)n1 +COc1ccc(CNc2ccc(NC(C)=O)c(OC)c2)c(OC)c1 +COc1ccc(C(NC(=O)c2cc(C)oc2C)C2CCOCC2)cc1 +Cc1nc2cccnc2n1C1CCN(S(=O)(=O)c2cccnc2)C1 +CN(Cc1ccsc1)C(=O)c1ccc(S(=O)(=O)C(F)F)cc1 +CCN(Cc1ccccc1C)S(=O)(=O)c1cnn(C)c1 +CC(Cc1cnccn1)n1cnc2cc(C(C)(C)C)sc2c1=O +Cn1ncc2c(NC3Cc4ccccc4C3)nc(-c3ccncc3)nc21 +COc1ccc(NC(=O)C2CCC(=O)N2)cc1OC +CN(C)S(=O)(=O)N(C)C(c1cccnc1)c1ccc(F)c(F)c1 +CCc1nnc(NC(=O)CC23CC4CC(CC(O)(C4)C2)C3)s1 +CC(C)CN1CCN(C(=O)CC(F)(F)F)CC1 +COC(=O)c1ccc(C)c(NCC(=O)N(C)c2ccccc2)c1 +Cc1ccc(-n2nnc(-c3ccc(F)c(C)c3)c2N)cc1 +O=C(CCc1ccc2c(c1)OCO2)NC1CCCc2[nH]c(=O)ccc21 +Cc1csc(NC(=O)NCc2cc(Br)cs2)n1 +CC1CN(C(=O)c2cc(N)ccc2Cl)CCO1 +Cc1nn(CCO)c(C)c1CNc1ccc(F)cc1 +COc1ccc(Br)c(C(=O)NCC(=O)OC(C)(C)C)c1 +O=C(NCC(O)c1cccc2ccccc12)c1ccc(F)c(F)c1 +C#CCN1CCN(C(=O)NCC(C)(C)N2CCOCC2)CC1 +CC(O)c1c(-c2cccs2)nc2ccc(F)cn12 +CC(C)(C)C(=O)CNC(=O)C1CCC(=O)N1Cc1cccs1 +CC(C)(C)NC(=O)COc1ccc(Cl)cc1CNc1ncn[nH]1 +Cn1cc(CNc2ccc(S(=O)(=O)C(F)F)cc2)cn1 +CCOc1ccc(-c2ccc(C#N)c(=O)n2CC(=O)NC)cc1 +CS(=O)(=O)c1ccc(OS(=O)(=O)c2ccccc2Cl)cc1 +Cc1cccc(C(=O)NC(C(=O)NC(C)C(C)C)C(C)C)c1 +CC(=O)N1CCCC1C(=O)NCCc1ccc(F)cc1 +CCc1ccc(-n2cc(C)c(C)c(C#N)c2=O)cc1 +CN1CCN(C(=O)CSc2cccc3cccnc23)CC1 +Cc1cc(NC(=O)c2nnn(-c3cc(Cl)ccc3C)c2C)no1 +CSc1ccn(Cc2c(Cl)cccc2Cl)c(=O)n1 +Cc1cc(C)n(C2CN(C(=O)c3cn4ccsc4n3)C2)n1 +Oc1cc(O)cc(C2NCCc3c(O)ccc(Cl)c32)c1 +CCOc1ccc(CCC(=O)Nc2ncccc2C)cc1 +Nc1cccc(CC(C(=O)N2CCCC2)c2cccs2)c1 +CC(=O)N1CCC(C(=O)Nc2nc(-c3ccc(C)s3)n[nH]2)CC1 +CCCOc1ccc(NC(=O)N(C)Cc2cnn(C)c2)c(C)c1 +CCOC(=O)N1CCN(C(=O)C2CC(=O)N(c3ccccc3)C2)CC1 +O=C(NCCN1CCOCC1)c1ccc(NC(=O)c2cc[nH]n2)cc1 +CC1CCCC(NC(=O)CCn2cnc3ccccc32)C1C +CCc1nc(C2CCCN2C(=O)c2cc(C3CC3)on2)no1 +CCN(C(=O)c1ccncc1F)c1ccc(Br)cn1 +COc1ccc(NC(=O)c2cn3cc(Cl)ccc3n2)cc1OC +CC(C)CNS(=O)(=O)c1ccc(CNC(=O)c2cccnc2)cc1 +CC(=O)Nc1ccc(OC(=O)c2sc(C)nc2C)cc1 +CC(C)(C)OC(=O)N1CCC2(CCC(=O)O2)CC1 +Cc1cccc(C)c1OCCC(=O)Nc1nnc(C(F)(F)F)s1 +CN(Cc1nnc(-c2ccccc2)o1)C(=O)C1CCCCC1 +Cc1csc(SC(C)C(=O)NCCc2cccs2)n1 +Cn1ncnc1CCNC(=O)NC1CCCCc2ccccc21 +c1ccc(-n2cc(CNc3cnn(-c4ccccc4)c3)cn2)cc1 +Cc1cccc(CC(=O)N2CCN(C(=O)c3ccc(=O)[nH]c3)CC2)c1 +CNC(=O)c1ccc(=O)n(Cc2ccn(C)c(=O)c2)c1 +CN(CCOc1ccc(Cl)cc1)C(=O)NC1CCCc2occc21 +Fc1cc(C(F)(F)F)cc2c1C(c1cc[nH]c1)NCC2 +N#Cc1cccc(CNC(=O)CCN2C(=O)CCc3ccccc32)c1 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+OCc1cc2c(cc1OCc1ccncc1)OCO2 +Cc1ccc(CNC(=O)c2c(C)sc3ccn(C)c(=O)c23)o1 +COc1ccc2nc(N3CCCC3)c(CCC#N)cc2c1 +Cc1ccc(OCC(=O)NCCc2nc3ccccc3[nH]2)c(C)c1 +CC(NC(=O)c1ccsc1)c1ccc(-n2ccnc2)cc1 +Brc1ccccc1NCc1ccncc1 +O=C(OCc1nnnn1-c1ccccc1)C1CC1(Cl)Cl +CCOC(=O)CN(CC)C(=O)Nc1ccc(F)cc1 +C#Cc1cc(F)c(NC(=O)c2ccc(C)cc2)c(F)c1 +c1csc(-c2nc(CSc3nncs3)co2)c1 +CC(C)(C)NC(=O)C1CCCCN1C(=O)c1cccc2ccccc12 +CCn1nccc1C(=O)Nc1nnc(-c2ccc(OC)c(OC)c2)o1 +CCn1nc(CC(C)C)cc1C(=O)N1CCCC1CO +CCc1sc(C(=O)Nc2cccnc2-n2cncn2)cc1C +CCOc1ccccc1C(=O)N1CCC(Nc2ncccc2F)CC1 +O=S(=O)(Nc1ccc(Oc2cccnc2)nc1)N1CCCCC1 +CC(C)CC(C#N)CCC(=O)N1CCCCCC1 +COc1cc(C(=O)NCCc2ccccn2)cc(Cl)c1OC(C)C +CCN(CC)S(=O)(=O)c1cc(C)c(C)c(NC(N)=O)c1 +CCc1cnc(CNC(=O)NCC(O)C2CC2)s1 +COC(=O)NCC(=O)Nc1ccccc1NS(C)(=O)=O +O=C(c1ccc(COc2ccccc2)cc1)N1CCCC1 +CC(=O)C(Cc1ccccc1)NC(=O)CSc1ccccn1 +Cc1n[nH]cc1CNC(=O)COc1ccccc1C(C)C +Oc1cc(O)cc(C2NCCc3c2ccc(Cl)c3F)c1 +COc1cccc(OC)c1-c1cc(C#N)c(=O)n(C)n1 +COc1ccc(OCCN2Cc3ccc(N)cc3C2=O)cc1 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+CS(=O)(=O)Nc1ccccc1NC(=O)c1ccc2c(c1)CCCC2 +CCCOc1cccc(NC(=O)c2cc(C)nc3c2c(=O)[nH]n3C)c1 +Fc1ccc(-c2noc(CNc3ccc4cc[nH]c4n3)n2)cc1 +Cc1cccc(OCCNC(=O)c2sc3nc[nH]c(=O)c3c2C)c1 +OCC1CCCN1c1cc(NCC2CCOCC2)ncn1 +Nc1ncc(Br)cc1C(=O)N1Cc2ccccc2C1 +CCOc1ncccc1NC(=O)Nc1c(C)nn(C(C)C)c1C +COC(=O)CCC(=O)Nc1cccc(Cl)c1F +CCOc1ccc(NC(=O)Cc2noc3ccccc23)cc1 +COc1ccc(F)c(NC(=O)N(C2CC2)C(C)c2ccco2)c1 +O=C(CC1(O)C(=O)Nc2ccccc21)c1cccnc1 +CCCNC(=O)CNC(=O)NCCc1cccc(F)c1 +CC(=O)NC(C(=O)N1CCN(C(C)=O)CC1)C(C)C +Cc1cc2c(cc1S(=O)(=O)NCCC(C)C)OCC(=O)N2 +CCC(C)N(C)C(=O)Nc1ccc(C)c(-n2cnnn2)c1 +Cc1cc(C(=O)NCc2c(C)n[nH]c2C)cc(S(N)(=O)=O)c1C +CCC(C)(CO)NC(=O)c1csc(C(C)C)n1 +CCCn1nccc1C(=O)Nc1nc2ccc(C)cc2s1 +O=c1[nH]c(=O)n(COCc2ccccc2)c2ccccc12 +Cc1[nH]ccc1C(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +Cc1cc(C)cc(N(C)C(=O)c2cc(Cl)ccc2-n2cnnn2)c1 +CC(=O)NCC1CCCN(C(=O)Nc2ccc(C#N)cc2)C1 +CC(O)CN(CCO)C(=O)c1cccc(Br)c1 +CCn1cc(NC(=O)NC(C)c2ccc3c(c2)OCCCO3)cn1 +NC(=O)CSc1ccccc1NCC1CCC=CO1 +Cc1cc(C(=O)OCC2CC2C)ccc1N1CCNC1=O +Cc1c(C(=O)NCc2ccnc(OC(C)(C)C)c2)cnn1CC(C)C +COc1ccc(CCC(=O)N(C)C(C)C)cc1F +CNC(=O)c1ccc(Cl)c(NC(=O)c2cccc(C)c2C)c1 +COc1cc(S(=O)(=O)Nc2ccccn2)c(OC)cc1C +N#CCCN(C1CC1)S(=O)(=O)c1ccc(Cl)c(Cl)c1 +CS(=O)(=O)N1CCC(C(=O)N2CC(O)C2)CC1 +NC(=O)c1csc(CN(CCc2cccc(F)c2)C2CC2)c1 +COc1ccc(NC(=O)Cn2c(=O)sc3ccccc32)c(OC)c1 +CSc1cccc(NC(=O)CCNc2ncccn2)c1 +CCOCCNc1ccc(F)cc1Br +COc1cc(F)c(Cn2ncc(N(C)C)cc2=O)cc1OC +CC1CCCCC1NC(=O)CCc1nc2ccccc2[nH]1 +CCOC(=O)CC1C(=O)NCCN1C(=O)c1c(F)cccc1F +C=CCNS(=O)(=O)c1cccc(C(=O)NC2CCCOC2)c1 +CC(=O)c1ccc(NC(=O)N2CCN(c3cccc(O)c3)CC2)cc1 +CC1(O)CCN(c2cncc(C(N)=O)n2)CC1O +COc1cccc(C(=O)OCc2cc3ccccc3[nH]c2=O)c1 +CC(=O)Nc1ccc(NCc2nnc3n2CCCCC3)cc1 +CC(C)(C)C(=O)NCC(=O)Nc1ccc(Br)cc1O +NC(=O)c1csc(C(=O)Nc2ccccc2Cc2ccccc2)c1 +CC(=O)N1CCC(C(=O)OCCc2ccc3ccccc3c2)C1 +O=S1(=O)N=CN(Cc2ccc(F)cc2Cl)c2ccccc21 +CCN(Cc1ccoc1)c1ccc(C(=O)Nc2nncs2)cn1 +Cc1cc(NC(=O)CCn2cnc3sccc3c2=O)n(C)n1 +COCCNC(=O)Cc1coc2cc(OC)ccc12 +O=S(=O)(Nc1ccccc1Cl)c1ccc2c(c1)OCCO2 +CC=CCn1c(C(=O)NCc2ccccn2)cc2c(OCC)cccc21 +Cc1nnc(NC(=O)CCn2ccc3ccc(F)cc32)s1 +CCOC(=O)CCC(=O)NCC#Cc1ccccc1Cl +CC(C)C(=O)N1CCC(CCOc2ccncc2)CC1 +CCc1nc(C)c(C(=O)N(C)CCn2cccn2)s1 +COc1cccc(C(=O)NCCn2ccnc2-c2ncccn2)c1 +Cc1cccc(-n2cc(C(=O)N3CCc4cc(F)ccc4C3)nn2)c1 +O=C(CCn1ncc(=O)c2ccccc21)OCC(F)(F)F +CC(COc1ccc(F)cc1)NS(=O)(=O)c1cn[nH]c1 +COc1ccccc1C(O)CNC(=O)Cc1cccs1 +O=C(Nc1ccc(F)cc1)C1CCCN(c2ccc3nncn3n2)C1 +O=C(C#Cc1ccccc1)Nc1cccn(Cc2ccc(F)cc2)c1=O +COc1ccccc1CN(C(=O)c1cccc(N)c1)C1CC1 +O=C(c1cnc2ccccn12)N1CCc2ncnc(NC3CC3)c2CC1 +CC(=O)NC(CC(=O)NCc1ccco1)c1ccc(C)cc1 +O=C(CC1CCOCC1)Nc1cc(Cl)c(O)c(Cl)c1 +CCc1nnc(NC(=O)CNC(=O)c2ccn(C)n2)s1 +O=C(NC1CC1)N1CC2CN(Cc3cccnc3)C(=O)C2C1 +Cc1cc(C)c(S(=O)(=O)N2Cc3cncnc3C2)cc1C +CN(CCO)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +C=CCNC(=O)c1ccc(NC(=O)c2scnc2C2CC2)cc1 +CC(=O)Oc1ccc(C(=O)N2CCCC(C)C2)cc1 +CCCCS(=O)(=O)N1CCCC1Cc1ccccc1OC +CS(=O)(=O)NCC1CCN(C(=O)c2ccccc2F)CC1 +Cc1nnc(-c2ccc(S(=O)(=O)N3CCc4ccccc4C3)o2)o1 +CC(C)NC(=O)CCC(=O)c1ccc(Cl)c(N)c1 +CC(c1ccc(Cl)cc1)N1CCN(Cc2n[nH]c(=O)[nH]2)CC1 +C=CCNC(=O)Nc1ccc(C(=O)NC2CCOCC2)cc1 +CCc1cccc(C)c1NC(=O)C1CC(=O)N(CCOC)C1 +CC(C)OCc1ccccc1CNC(=O)c1nccn2ccnc12 +Cc1noc(C)c1COC(=O)Cc1c(F)cccc1Cl +COc1cc(CNC(=O)c2cncc(Br)c2)ccc1O +Cn1nccc1CNC(=O)c1cccc2[nH]ccc12 +COC(=O)CNC(=O)c1ccc(NC(=O)c2ccoc2C)cc1 +COc1ccc(CNC(=O)c2ccccc2-c2ncc[nH]2)cc1F +CCCOc1ccccc1NC(=O)N(C)CCOC +CCOc1cccc(NC(=O)c2c(F)ccc(OCC)c2F)n1 +CNc1cc(C(=O)N(C)Cc2cn[nH]c2-c2ccccc2)ccn1 +CCOC(=O)c1ccccc1N(C)C(=O)c1sc2nccn2c1C +COc1ccc(CC(=O)Nc2nc(-c3cccc(N)c3)cs2)cc1 +CC(NS(=O)(=O)N(C)CCC#N)C(C)(C)c1ccccc1 +Cc1ccc(C(C)NC(=O)c2cccc(O)c2)s1 +COC1CCCCC1OC(=O)C1CCCN(C(=O)N2CCCC2)C1 +COCCN1CCN(C(=O)Nc2cnn(CC(F)F)c2)CC1=O +COc1ccc2c(c1)c(CO)cn2-c1ncccn1 +O=S(=O)(C1CC1)N1Cc2[nH]nc(COCc3nccs3)c2C1 +CCN(CC)c1ccc(C(=O)NS(=O)(=O)c2ccc(C)cc2)cc1 +O=C(Nc1ccc2c(c1)COC2)c1cccc(C2OCCO2)c1 +c1nc(N2CCOCC2)cc(N2CCN(Cc3ccsc3)CC2)n1 +CCc1ccc(O)c(C(=O)N2CCN(CCOC)C(=O)C2)c1 +CN1CC(=O)N=C1Nc1cc(N)n(-c2cccc(Cl)c2)n1 +COC(=O)c1ccc(Cn2cc(Br)ccc2=O)o1 +COc1ccccc1Nc1nc(C)nc2c1CCC2 +Cc1cc(C)c(C(=O)N2CCn3cccc3C2c2cccnc2)c(=O)[nH]1 +O=C(Nc1cccnc1)N(CC1(O)CCCC1)CC1(O)CCCC1 +O=C1CCN(C(=O)c2ccc3c(c2)CCCO3)CC1 +CC(C)C(C)N(C(=O)c1cccc(C(N)=O)c1)C1CC1 +CC(C)CNC(=O)CN1CCN(C(=O)c2ccc(O)cc2)CC1 +CCNC(=O)c1ccc(OC(=O)c2cnc3ccc(C)cn23)cc1 +CC(=O)Nc1ccc(C)c(NC(=O)N2CCOC(C)(C)C2)c1 +CC(C)n1c(SCCNS(C)(=O)=O)nc2ccccc21 +Cc1cccc(NC(=O)CSc2nnnn2C)c1C +Cc1ccc(N2CCN(C(C)C#N)CC2)c(Br)c1 +CCOC(=O)C1CCCN(S(=O)(=O)c2ccc(F)cc2F)C1 +Oc1cc2c(cc1OC(F)(F)F)C(CC1CC1)NCC2 +COCCN1CC(C(=O)Oc2ccc(C(C)C)cc2)CC1=O +CCN(CC(=O)N(C)C)C(=O)Cn1cnc(N)n1 +O=C(C1CCCN1C(=O)c1ccco1)N1CCNCC1 +CC(C)c1cc(C(=O)NCc2csc(=O)[nH]2)nn1-c1ccccc1 +O=C(NC1CCCCNC1=O)c1cccc2cccnc12 +CC(=O)NCC1CCCN(C(=O)CN(C)c2ccccc2)C1 +Cc1oc(CO)cc1C(=O)OCC(=O)Nc1ccccc1C#N +CC(C(=O)N1CCN(c2cnccn2)CC1)n1cncn1 +Cc1cccc(NC(=O)CNC(=O)C2CC3CCC2C3)c1C +Cc1ccsc1CN(CC(C)C)C(=O)CCn1cnnn1 +COc1ccc(OC)c(C2CCCN2C(=O)C(C)NC(C)=O)c1 +Cn1c(CCC(=O)N2CC3C4CCC(O4)C3C2)nc2cccnc21 +O=C(NCc1cccc(F)c1)c1ccnc(OC2CCC2)c1 +CC(C)(C)OC(=O)N1CCC(S(=O)c2ncccc2C#N)CC1 +CC(C)C(=O)N1C(C(=O)N2CCN(C)CC2)COC12CCCCC2 +CCNC(=O)c1c(C)nc(N)nc1C(C)Oc1ccccc1OC +Cc1cccc(OC(C)C(=O)N(C)Cc2ccc(C)o2)c1 +O=C1Nc2ccccc2CC1CCC(=O)N1CCOC2CCCCC21 +COc1ccc(NC(=O)CNc2c(F)cccc2F)cc1 +COCc1cc(NCc2ccc(C(C)O)c(C)n2)n2ncnc2n1 +CC1(C)Cc2cccc(OCCC(=O)Nc3cccnc3)c2O1 +NC(=O)Cn1cc(NC(=O)NCCc2ccsc2)cn1 +CC(O)CN1CCN(C(=O)c2ccc(F)cc2Br)CC1 +Cc1nc2nc(C)c(CCC(=O)NCc3ccco3)c(C)n2n1 +Cn1cnc2cc(C(=O)NCc3ccnc(OC(C)(C)C)c3)ccc21 +CCOc1ccc(OC(=O)c2csc(-c3ncccn3)n2)cc1 +Cc1cnn(CCC(=O)Nc2cc(C#N)ccc2OC(F)F)c1 +CCCS(=O)(=O)N1CCC(c2cnn(-c3ccccc3)c2)CC1 +CN(C)C(=O)CCNC(=O)Nc1cnn(CC2CCCO2)c1 +COC(=O)c1ccc(C(=O)NCc2ncccc2C)cc1 +CCn1nnc2cc(C(=O)NC(C)(C)C(=O)OC)ccc21 +CC(=O)c1ccc(N(CCO)C2CC2)c(Cl)c1 +Cc1cc(C)cc(NC(=O)CC(NC(N)=O)c2ccc(Cl)cc2)c1 +NC(=O)N1CCC(OCC2CC2)C1Cc1ccncc1 +Cc1ccc2ncc(C(=O)NCCCOCC3CCCO3)n2c1 +FC(F)(F)c1ccc(-c2n[nH]cc2-c2ccncn2)cn1 +CCC(C)n1ncc(C(=O)NCC2(C3CC3)CC2)c1C1CC1 +CC(C)OCc1cc(C(=O)N2CCCC(c3ccn[nH]3)C2)ccc1F +COc1ccc(F)cc1NC(=O)Cc1ccc(C)s1 +COc1cc(Br)c(NC(=O)NC(C)C)cc1OC +CCN(CC)S(=O)(=O)c1cc(C)c(Cl)cc1C +COc1ccc(OCCCNC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +CCc1cc(N2CCCC(CO)C2)n2nc(C)c(C)c2n1 +CC(NS(=O)(=O)c1ccccc1F)C(=O)OCc1ccccc1 +COCCNC(=O)c1ccc(NC(=O)CC2CCCC2)cc1Cl +CCC(CNC(=O)N1CCCC(O)C1)Oc1cccc(C)c1 +COCCOC(=O)c1cc(C(=O)Nc2ccccc2)c(=O)[nH]c1C +CC(=O)Nc1ccc(NCc2nc(C(C)C)no2)c(C(F)(F)F)c1 +COC(=O)c1cnc(NC(=O)c2cn(-c3ccccc3)nn2)s1 +Cn1cc(C(O)CNC(=O)COc2ccccc2)c2ccccc21 +CN1C(=O)CCc2cc(NC(=O)c3cccc(F)c3)ccc21 +CC(Cn1cccn1)NC(=O)C1CCN(S(C)(=O)=O)CC1 +O=C(CN1CCc2sccc2C1)N1CCCc2cc(F)ccc21 +Cc1[nH]c2ccnn2c(=O)c1CC(=O)Nc1ccc2c(c1)CCC2 +CCn1c(SCc2ccc(C#N)cc2)nnc1-c1ccco1 +Cc1noc(C)c1NC(=O)N1CCCC1c1nc2ccc(F)cc2[nH]1 +CCN(Cc1c(C)nn(CC)c1C)S(=O)(=O)c1ccc(C)c(C)c1 +CCC(C)Cc1nc(C2CCOCC2)nn1Cc1ccccc1 +CCOc1ccc(CN(C)C(=O)NCc2cscn2)cc1 +Cc1nc(CN)nc(-c2cn(C)c3ccccc23)n1 +Cc1ccc(OCC(=O)OCC(=O)N2CCNC(=O)C2)cc1C +CCc1ccc(OCC(=O)N2CCN(CC)CC2)cc1 +OC1Cc2ccccc2C1Nc1cncc(Br)c1 +CC(C)c1nnc(CN(CCc2cccc(F)c2)C2CC2)o1 +Cc1cc2c(=O)n(CC#Cc3ccc(F)cc3)cnc2s1 +O=C(CCC(=O)c1ccc(Br)cc1)OCc1cccnc1 +CCOC(=O)C1CCCN1Cc1nc(N)nc(N)n1 +CS(=O)(=O)c1ccccc1NC(=O)NCc1ccccn1 +COC(=O)c1ccsc1NC(=O)C1CCN(c2ncccn2)CC1 +CC(=O)Nc1ccc(C(=O)N(C)Cc2ccccc2Cl)cc1 +CS(=O)(=O)Nc1ccccc1C(=O)Nc1cccc(F)c1 +COc1ccc(NC(=O)CSc2nnc(C(C)C)n2N)cc1 +Cc1noc(C)c1C(=O)N1CCCC1c1cccs1 +Cc1cc(CCNC(=O)c2ccc3ccccc3n2)on1 +CC(O)CNC(=O)c1cnn(-c2ccccc2F)c1-n1cccc1 +CCc1onc(C)c1NC(=O)C1CCCN1C(=O)C1CCCC1 +CC(=O)C(C)Oc1cc(O)c2c(=O)cc(-c3ccccc3)oc2c1 +COC(=O)c1sccc1S(=O)(=O)Nc1ccc(F)c(F)c1 +CCOc1cccc2c1OCC(=O)N(c1ccc(OC)cc1)C2 +CCCCNC(=O)CCNC(=O)c1ccsc1 +CC(C)Oc1cccc2c1c(NC(=O)C1CCOCC1)nn2C +O=C(Nc1ccc(OC(F)F)cc1)c1cncn1-c1ccccc1 +Cn1cc(C(=O)Nc2ccccc2Cl)c(=O)c2cc(Cl)ccc21 +O=C(CN1C(=O)c2cccc3cccc1c23)NCc1ccccc1 +N#CCCNC(=O)COc1cc(Cl)ccc1Cl +CC(C)CC(=O)N1CCC(n2c(=O)oc3ccc(Cl)cc32)CC1 +Cc1ccc(CCC(=O)N2CCc3ccccc32)cc1 +O=C(CCN1C(=O)COc2ccccc21)NCc1cscn1 +CN1C(=O)Cc2ccccc2C1C(=O)NC1CCCCC1 +COc1nc2c(cc1C(=O)NCc1csc(N(C)C)n1)CCC2 +COc1cc(C(=O)N2CCSc3ccccc32)cc(OC)c1OC +COc1ccc(F)cc1C(C)NC(=O)NCC1CC1C +COCCCn1ccc(NC(=O)N2CCCCC2c2cn[nH]c2)n1 +CCOC(=O)c1nc2cc(OC)c(OC)cc2[nH]c1=O +CC(C)CC(=O)OCc1cc(=O)n2nc(C(C)C)sc2n1 +CCNC(=O)c1ccc(NC(=O)N(CC)Cc2ccccc2)c(C)c1 +Cc1ccccc1SCC(=O)NCc1ccoc1 +Cc1ncsc1CN(Cc1ccccc1)C(=O)C1CNCC(=O)N1 +CCN(Cc1ccccc1NC(=O)CCC(C)(C)C)C(C)=O +CCN(Cc1ccco1)C(=O)Nc1c(C)cccc1C +N#Cc1ccccc1Cn1c(CO)nc2cccc(F)c21 +O=C(OCC(F)F)c1ccc(NC(=O)C2CC2)cc1 +CCCC(=O)NCc1ccnc(Oc2ccc(OC)cc2)c1 +CN1CCOC(C(O)C(Cl)(Cl)Cl)C1=O +Cc1cc(C(=O)Nc2cccc(C(=O)N3CCCCC3)c2)n(C)n1 +CCc1ccc(C(=O)N2CCC(n3cccc3C(=O)OC)CC2)o1 +COC(=O)Cc1ccc(NC(=O)Cc2ccc(OC)cc2)cc1 +Cc1nc(-c2ccco2)ccc1C(=O)NCC(O)c1cccc(F)c1 +O=C(NC1CCOC2(CCCC2)C1)c1cccnc1OCC(F)F +CC(Cc1ccccc1F)NC(=O)CCc1nc(C(C)C)no1 +CC1=C2C(O)C(=O)OC(c3ccoc3)C2(C)CCC1O +Cc1cc(C)c(CCn2nc(C)c(N)c2C)c(C)c1 +CN(CC(=O)N1CCCC1)c1ncnc2c1cnn2CCC#N +CCN(C(=O)CNC1(c2ccc(F)cc2)CCOCC1)C1CC1 +CCOc1ccc(CC(=O)NCC2(O)CCc3ccccc32)cc1 +Cc1cc2nc(C3CCC3)n(CCCO)c2cc1C +O=C(Cn1c(=O)oc2ccccc21)NCc1nc2ccccc2s1 +Cc1ncncc1C(=O)NCc1ccc(F)c(F)c1F +CC(NC(=O)Nc1ccc(F)cc1)C(=O)NC(C)(C)C +CC(C)c1nc(CN(C)C(=O)c2ccc(-c3cc[nH]n3)cc2)cs1 +COc1ncc(C(=O)NC(c2ccncc2)c2ccc(C)cc2)cn1 +CCNC(=O)Nc1cc2c(cc1N)OCC(=O)N2 +COc1ccc(Cl)cc1C(=O)Nc1ccc2c(c1)CC(=O)N2 +Cc1ccc2cnn(C(=O)NCc3ccccc3)c2c1 +CCOC(=O)N1CCN(C(=O)Nc2cc(Cl)cc(Cl)c2)CC1 +Cc1ccc(N2CC(C(=O)N(C)C(C)CC#N)CCC2=O)cc1C +COc1c(C)cnc(CN(C)C(=O)CNC(=O)c2ccccc2)c1C +COc1ccccc1CNC(=O)c1cn2ccc(C)cc2n1 +Cc1noc(C)c1CC(=O)NC(C)c1ccccc1Cl +CN1CCc2nc(NC(=O)c3ccc4c(c3)OCO4)sc2C1 +CN1CCN(C(=O)CCC(=O)c2cc(F)ccc2F)CC1 +CCc1nc2n(n1)CC(NCc1nc3ccccc3s1)CC2 +CCN(CC(F)(F)F)c1nc2c(s1)C(=O)CCC2 +Cc1csc(C(C)(C)NCC(=O)NCC2Cc3ccccc3O2)n1 +Cc1ccc(N2CC(C(=O)NC(C)Cn3cccn3)CC2=O)c(F)c1 +Cc1c(F)cccc1NCc1cc(=O)n2ccccc2n1 +CC(C)(C)OC(=O)CNC(=O)CCn1cnc2sccc2c1=O +O=C1CCCN1CCC1CCN(C(=O)Cc2ccc(CO)cc2)CC1 +Cn1ncc(N2CCC(CNc3nc4ccccc4o3)CC2)cc1=O +Cc1ccc(NC(=O)c2ccc(N3CCOCC3)nc2)cc1F +COc1ccccc1N1CCN(Cc2cccc3nccnc23)C(C)C1 +Cc1ccccc1OC(=O)Cn1nc(C)c2ccccc2c1=O +Cc1nn(Cc2nnc(-c3ccc(F)cc3)o2)c(C)c1CCO +COC(=O)c1cccc(COC(=O)c2cnn(-c3ccccc3)n2)c1 +Cc1cccc(OCC(=O)NCc2ccccc2F)c1 +CC1CC1C(=O)N(C)Cc1csc(C#CCO)c1 +CC(=O)Nc1ccc(CN2CCOC(C)(c3ccccc3)C2)cc1 +Cc1cccc(OC(=O)C2CCCCN2S(C)(=O)=O)c1 +Cc1ccc(-c2cc(C(=O)NCc3cscn3)on2)cc1 +C#CCNC(=O)c1nnn(-c2ccccc2Cl)c1C +O=C1COc2cc(Cl)ccc2N1Cc1nc(-c2cccnc2)no1 +Cc1cc(C(=O)NC2CCN(c3ncc(F)cn3)CC2)no1 +O=S(=O)(Oc1ccc2c(c1)OCO2)c1cccs1 +COc1ccc(SCCC(=O)N(C)Cc2cccc(C#N)c2)cc1 +CC(C)(C)n1ncc2c(=O)[nH]c(NCCC(=O)N3CCCC3)nc21 +CC(C)CC(NC(=O)c1ccccc1F)c1nc2cccnc2n1C +Cc1cccc(C(=O)NCCCNC(=O)c2cccs2)c1C +CCN(C(=O)c1ccc(OC)nn1)c1ccccc1 +C#CCN1CCN(C(=O)c2c(O)cc(Cl)cc2Cl)CC1 +CCN(Cc1ccccc1NC(=O)NCCC1=CCCCC1)C(C)=O +COc1cccc(COC(C)C(=O)N2CCC(C(N)=O)C2)c1 +CCOc1ccc(C(=O)Nc2nc3ccc(NC(C)=O)cc3o2)cc1 +CN(C)C(=O)c1cc2c(Cl)ccc3c2n1CCO3 +COc1cccc(CNc2nc3ccc(Cl)cc3n3cnnc23)c1 +O=C(CCc1cccnc1)Nc1cc(-c2ccccc2F)no1 +Cc1cc(C(=O)NC(C)C)ccc1NC(=O)NC(C(N)=O)C(C)(C)C +Cc1nc(=O)[nH]c(C)c1CCC(=O)NCCc1ccc(Cl)cc1 +Cc1[nH]c2ccccc2c1C(=O)NCc1ccc(NC(N)=O)cc1 +CCNc1nnc(-c2nnc3sccn23)s1 +CCS(=O)(=O)NCC(=O)Nc1ccc2c(c1)COC2 +O=C(CSc1nc2ccccc2s1)NCC(=O)c1ccccc1 +CC(C)C(=O)c1ccccc1NC(=O)C1COc2ccccc21 +NC(=O)C(NC(=O)c1cncc(F)c1)c1ccc(F)cc1 +CCSc1ncc(Cl)c(C(=O)N2CCOCC2)n1 +CCCOc1ncccc1CNC(=O)c1c(C)cc(C)[nH]c1=O +O=C(COC(=O)c1ccncc1)Nc1ccccc1 +CC(=O)NC(Cc1cc(N(C)C)nc(C2CC2)n1)c1cccc(C)c1 +CC1Oc2cc(CO)ccc2N(C(C)c2ccccc2)C1=O +Cc1cc(NC(=O)CCc2c(C)[nH]c(=O)c(C#N)c2C)no1 +Cc1cn2c(CN3CCN(c4cccs4)CC3)c(C)nc2s1 +Cc1ncncc1C(=O)N1CCOC(C(=O)NC2CCCC2)C1 +Cc1ccc(C(C#N)NS(=O)(=O)c2ccccc2C)cc1 +O=C(COc1cccc(CO)c1)NCc1ccco1 +COc1cncc(N(C)CCCc2n[nH]c(N)c2C#N)n1 +NC(=O)c1cc(NC(=O)c2c(F)ccc(F)c2F)c(F)cc1F +COC(=O)C1=C(C)C(C(=O)NCC2CCCCC2)=NC1C +CCOC(=O)C1=C(C)NC(=O)NC1c1cc2ccccc2[nH]c1=O +CCNC(=O)N(C)CCOc1cc(C)cc(C)c1 +O=C(c1ccnc(-n2cncn2)c1)N1CCN(c2nccs2)CC1 +C#CCN(Cc1ccc(F)cc1)C(=O)c1nccnc1N +Cc1cc(CNC(=O)C2CCN(S(C)(=O)=O)CC2)no1 +COc1nccnc1N1CCC(NC(=O)COc2ccc(F)cc2)C1 +COCc1cn(C2CCN(S(=O)(=O)c3cccs3)CC2)nn1 +O=c1cc(C2CCCN(c3nccc(-c4cccnc4)n3)C2)nc[nH]1 +O=C1NC2CCCN=C2N1CCN1CCOCC1 +O=C(c1ccoc1)N1CCN(C(=O)C2CCCC2)CC1 +CC(C)(C)N1CC(C(=O)Nc2nnc(C(F)(F)F)s2)CC1=O +CCc1ccc(NS(=O)(=O)c2cccc(C(N)=O)c2)cc1 +CSc1ccc(NC(=O)c2ccccc2)cc1C#N +CCN(CC(C)(C)O)C(=O)NCc1cc(Cl)cc2c1OCC2 +CCn1ncc(Cl)c1CN(C)C(=O)c1noc2c1CC(C)CC2 +CC(=O)c1c[nH]c(C(=O)OCc2cc(=O)n3cc(Cl)ccc3n2)c1 +Cc1ccc(-c2n[nH]c(SCC(C)(C)O)n2)cc1 +CN(CCCNC(=O)C1CC(=O)OC12CCCC2)c1ccccc1 +CCc1nnsc1C(=O)NCCc1nc2cc(F)ccc2n1C +CC1(C(=O)N2CCN(C(=O)CC(F)(F)F)CC2)CCCCCC1 +CC(C)NC(=O)CNc1cc(C(F)(F)F)ccc1F +CCOC(=O)c1ccc(NC(=O)c2cc(Cl)c[nH]2)cc1 +CN1CCCN(C(=O)c2cnccn2)c2nc3ccccc3nc21 +O=C(OCCc1ccc(F)cc1)C1COc2ccccc21 +Cc1cc(CN(C)C(=O)COc2ccccc2F)no1 +O=C(COCc1cc(-c2ccc(F)cc2)on1)NCc1ccco1 +COc1cc(O)cc2c1CCNC2c1ccncc1C +CCOc1ccc2nc(N3CCN(C(=O)C4CCC4)CC3)sc2c1 +O=C(NCC1COCCO1)C1CC1c1cccc(F)c1 +c1cnc(NCc2cncc3c2CCN(Cc2cccs2)C3)nc1 +COc1ccc(CNC(=O)c2nccnc2N)c(OC)c1 +COCCN1CC(=O)N(c2ccc(C)cc2)CC1Cc1ccccc1 +COCCNC(=O)c1ccc(-n2c(C)nc3ccccc3c2=O)cc1 +CCOC(=O)C=C(NCc1ncc(C)s1)C(F)(F)F +Cc1cn(C(C)C)c(=O)c(C#N)c1-c1cccc(O)c1 +COc1ncnc2c1CN(Cc1cnc(-c3ccccn3)s1)CC2 +COc1cc(C#N)ccc1CNc1ccc(C)c(O)c1 +CNC(=O)c1ccc(CNC(=O)Cc2cn3cccc(C)c3n2)cc1 +CC(=O)Nc1ccc(C(=O)COc2cc(C)cc(C)c2)cc1 +COc1ccc2c(c1)CCCC2CC(=O)N(C)CCN1CCOCC1 +Cc1cc(C)cc(C(=O)NCC(=O)NC(C)CCc2ccco2)c1 +CC(=O)NCCNc1cc(N2CCCCC2)ncn1 +O=C(Nc1ccccc1)c1nncn1Cc1ccccc1 +CCN(CC(=O)N(C)C)C(=O)c1cccc(C#N)c1 +FC(F)(F)c1ccccc1CNc1cnns1 +CCc1onc(C)c1NC(=O)NCc1cn2cc(Cl)ccc2n1 +CCC(C)C(=O)Nc1cccc(CNC(=O)NCc2ccco2)c1 +Cc1cccc(C(=O)NCC(=O)Nc2nccs2)c1C +COc1ccc(C(=O)N(C)CC2CCC2)cc1-n1cnnn1 +Cc1n[nH]c(C)c1NC(=O)COc1cc(Cl)c(Cl)cc1Cl +CCc1noc(CC)c1CC(=O)Nc1nn(-c2ccccc2)cc1C +CCn1nnc2cc(-c3noc(-c4ccccc4)n3)ccc21 +CCn1c(SCc2cccc(C(=O)N(C)C)c2)nnc1C1CC1 +CNc1nnc(-c2c(COC)oc3c2CCC3)s1 +CCc1nc(CCNC(=O)C2Cc3ccccc3O2)sc1C +Cc1cc(C)c(C(=O)NCc2ccc(C(=O)Nc3ccncc3)cc2)[nH]1 +C=CCN1C(=O)c2ccccc2NC1c1c[nH]c2ccccc12 +O=C(NCCC1COc2ccccc2O1)c1ccc(NCCO)nc1 +CC(NC(=O)c1cccnc1)c1cc(=O)[nH]c(-c2cccnc2)n1 +O=C1CCCc2nc3nc(-c4ccc(Cl)cc4)nn3cc21 +Cc1ccc(CNC(=O)c2nnc(CSc3ncn[nH]3)s2)cc1 +NS(=O)(=O)N1CCN(CC(O)c2ccccc2Cl)CC1 +CN1CCN(C(=O)c2cc(F)c(F)cc2Cl)CC1 +Cc1n[nH]c(C)c1NC(=O)CN1CCN(C)c2cc(F)ccc21 +CCNC(=O)CSc1ncc(-c2ccc(F)cc2)[nH]1 +COc1ccccc1NC(=O)CNC(=O)c1ccc2cncn2c1 +O=C(c1ccc(F)c(C(F)(F)F)c1)N1CCCC1c1ccsc1 +CCn1c(C)cc(C(=O)NCc2ccnc(OC)c2)c1C +COc1cccc(CNC(=O)Nc2ccc(F)cc2)c1 +CCCOc1ccccc1-c1ccc(C(C)=O)c(=O)n1CC +Nn1c(SCCOc2ccc(Cl)cc2)nnc1-c1ccco1 +N#Cc1cccc(NS(=O)(=O)c2ccc(F)c(F)c2F)c1 +O=C(NCc1ccccn1)c1cc2ccccc2cc1NC(=O)C1CC1 +CSc1ccc(-c2nc(-c3ccc(C#N)cn3)no2)o1 +COc1c(NC(=O)C(C)c2cccs2)c(C)nn1C +CCOc1cc(CCC#N)ccc1OCc1ccccc1 +Cc1occc1C(=O)Nc1nc2ccc(S(C)(=O)=O)cc2s1 +CCCN(C)C(=O)c1cc(S(=O)(=O)NCC)ccc1C +Cc1c(NC2CCN(C)C2=O)c(=O)n(-c2ccccc2)n1C +COc1nccnc1NCC(O)COc1cccc(Cl)c1Cl +COc1ccc2c(c1)CC(C(=O)Nc1nccn(C)c1=O)CO2 +COCCN(C)S(=O)(=O)c1ccc(Cl)cc1C(F)(F)F +CC(C)N(CCC#N)C(=O)Cc1ccc(Br)cc1 +COc1ccc(NC(=O)N2CCC(CC(N)=O)CC2)cc1 +CCC(NC(=O)c1cnn(C(C)CC)c1C1CC1)c1nccs1 +CCC(Sc1nncn1C)C(=O)Nc1nccs1 +O=C(Nc1nnc(Cc2ccccc2)s1)C1CC2CCC1C2 +COc1ccc(NC(=O)N2CCOC(C)(C)C2)c(Cl)c1 +CC(c1nnc(-c2cccs2)o1)N1CCOCC1 +Cc1cc2nccc(-c3ccc(-n4cnc5ccccc54)cc3)n2n1 +C#CCN(Cc1ccco1)C(=O)Nc1cnn(CC)c1 +Brc1cnc2c(N3CCC4OCCCC4C3)ccnc2c1 +O=C(Nc1ccc2c(c1)CCN2C(=O)c1cccnc1)c1cccs1 +O=C1CC(C(=O)NCCOc2cccnc2)c2ccccc2N1 +CN(C(=O)CCc1nc2ccccc2s1)c1ccccc1 +Cc1cc2cc(C(=O)N3CCC(N4CCOC4=O)CC3)ccc2o1 +CCNc1cc(C(=O)NCCNC(C)=O)ccn1 +O=C(NCCOc1ccccc1)c1csc(Nc2ncccn2)n1 +CN(Cc1ccccn1)C(=O)NCc1ccccc1-n1ccnc1 +Cc1nc(C)c(C(=O)Nc2cnc(-n3nc(C)c(C)c3C)nc2)s1 +COCCC(=O)N1CCC2C1CCC(=O)N2Cc1csc(C)n1 +O=C(c1ccc2[nH]c(CO)nc2c1)N1CCCC(O)(CO)C1 +Cc1cc2ccccc2n1CC(=O)Nc1cccc(-c2nnco2)c1 +CCOC1CCN(S(=O)(=O)c2ccccc2)C1Cc1cccnc1 +CCC(=O)C(C)Sc1nnc(-c2ccncc2)n1-c1ccccc1 +COCCNC(=O)CCNc1ccc(Br)cn1 +COc1cc(CCC(=O)NC(C)c2cccnc2)cc(OC)c1 +COc1ccc(C2=CCN(C(=O)c3cnccn3)CC2)cc1 +CCc1cccc(OCCN(C)C(=O)c2cc(C)nn2C)c1 +CCC1COCCN1CCOc1cccc(C#N)c1 +O=C(CCn1cnc2ccccc2c1=O)NC1=CC2=CC=NC2C=C1 +COc1ccc2oc(C(=O)Nc3ccc4c(c3)OCCO4)c(C)c2c1 +O=C(Cc1ccn(-c2ccc(F)cc2)n1)Nc1nc2ncccn2n1 +CC(C)Cc1nc2sc3c(c2c(=O)n1N)CC(C)(C)OC3 +Cc1nc(COc2ccc3c(c2)CCC(=O)N3)cs1 +CCNC(=O)C1CN(C(=O)Nc2ccn(-c3ncccc3Cl)n2)C1 +Cc1c(C(=O)OCc2nc3ccsc3c(=O)[nH]2)oc2ccccc12 +N#CCCS(=O)(=O)c1cc(Cl)ccc1Cl +O=C(COC(=O)c1cccc(F)c1)Nc1ccc2c(c1)OCCO2 +C#CCN(Cc1ccco1)C(=O)Nc1nccs1 +CCOC(=O)c1cccc(NCC(=O)N2CC(C)CC(C)C2)c1 +CC1CC(OC(=O)C(C)Sc2nncn2C)CC(C)(C)C1 +O=C(c1ccccc1Sc1ccccc1)N1CCC(O)CC1 +CC1CCCC(CO)(NC(=O)C2CCCCO2)C1 +CCOc1ccc(C(O)CNC(=O)c2ccc(C)cc2)cc1 +Cc1n[nH]cc1CNC(=O)c1cccc2ncccc12 +CCOC(=O)Cn1ccc(NC(=O)c2ccc3c(c2)OCO3)n1 +CCCCNC(=O)Cn1cnc2sccc2c1=O +CNC(=O)CCOc1ccc(NC(=O)N2CCCC3CCCC32)cc1 +CC(NC(N)=O)C(=O)NC1CCN(c2ccc(C(C)(C)C)cc2)CC1 +Cc1nc(-c2cccs2)c(CC(=O)NCc2ccc(F)cc2)s1 +CCCOc1ccccc1OCC(=O)N1CCC(C(N)=O)C1 +NC(=O)c1ccc(COC(=O)c2ccc(-n3cccn3)cc2)cc1 +CC(C)Oc1ccc(CNC(=O)c2ccc(-n3ccnn3)cc2)cc1 +Cc1cc(C)n(CC2CCCCN2C(=O)Cc2csc(C)n2)n1 +COc1cc(N2CC3COCC3(COc3cccnc3)C2)ncn1 +NC(=O)c1cc(-c2ccc(Br)cc2)no1 +O=C(NCCCCOc1ccc(Cl)cc1)c1cccnc1O +CCc1nsc(SCc2nc(CC(C)C)no2)n1 +O=C1COc2c(F)cc(NC(=O)NCC3=CCCCC3)cc2N1 +COCC(C)n1c(CCCC(=O)N2CCCC2)nc2cccnc21 +NS(=O)(=O)c1cccnc1Nc1ccc(Br)cc1 +CCCOc1ccc(S(=O)(=O)n2ccnc2)c2ccccc12 +NC(=O)c1cc(CCCOCc2ccccc2)ccc1F +Cc1ccc(CN(Cc2ccco2)S(=O)(=O)c2cccnc2)s1 +CN(C(=O)NCCC(=O)NC1CCCC1)C1CCCCC1 +Cn1cc(CCNC(=O)NCc2ccc(Br)cc2)cn1 +COC(=O)C(C)(C)NS(=O)(=O)c1ccc(OC)c(Cl)c1 +Cc1ccc(C(=O)Nc2ccc(Oc3ccccc3C#N)cc2)cn1 +Cc1ccc(C(=O)NCCNC(=O)c2ccc(=O)[nH]c2)cc1F +Cc1cccc(N(CC(=O)Nc2cccnc2)S(C)(=O)=O)c1 +CC(C)c1nc2cc(NC(=O)c3cc[nH]n3)ccc2o1 +CCOc1ccccc1NC(=O)c1ccc(S(C)(=O)=O)cc1 +CC(C)OCCSc1nnc(C(F)(F)F)n1N +COc1ccc(C)cc1NCCC(=O)Nc1ccc(C(N)=O)cc1 +Cc1cc(NC(=O)NCCCNS(C)(=O)=O)no1 +CCn1nc(C)c(NC(=O)Cn2ncc(Br)c2C)c1C +Cc1ccc(OCCN(C)C(=O)NCc2cccnc2)cc1 +Cc1cccc2cc(C#N)c(NCCNC(=O)Nc3ccccc3)nc12 +O=C(c1cncc(F)c1)N1CCC2C(CCC(=O)N2C2CC2)C1 +CC(Sc1nnnn1C1CC1)C(=O)N(C)Cc1ccccc1 +Cc1ncc(CN(C)C(=O)C2CC2c2ccco2)s1 +CSc1ccc(CN(C)C(=O)c2nc3nc(C)cc(C)n3n2)cc1 +Cc1cccc(NC(=O)C(C)OCC(F)(F)F)c1 +CC(c1nc(C2CC2)no1)N1CCN(Cc2nnc(C3CC3)o2)CC1 +CCCn1ccc(C(=O)NCC(C)c2ccc(F)cc2)n1 +Cc1ccc(C2(O)CCN(C(=O)c3ccc(Cl)cn3)CC2)nc1 +CC(=O)c1ccc(S(=O)(=O)NCc2cccc(N)c2)cc1 +Cc1ccc(CNC(=O)c2cn(-c3ccc(C)cc3)nn2)cc1 +O=C(c1ccco1)C(c1ccncc1)n1nnc2ccccc21 +CC(=O)c1cc(C(=O)N2CC(n3cc(-c4ccccc4)nn3)C2)n(C)c1 +COCc1ccc(C(=O)Nc2ccccc2N2CCC(O)CC2)cc1 +CCc1ccc(NC(=O)c2cc(S(N)(=O)=O)ccc2F)cc1 +Cc1ccc(-c2nnc(CS(=O)(=O)c3ccc(C)cc3)o2)cc1 +COc1ccc(C(=O)CNC(=O)c2ccc3ccn(C)c3c2)cc1 +O=C(c1ccc(-n2ccnc2)cc1)N1CCN(c2cccc(O)c2)CC1 +CCOc1ccc(C(=O)N(C)Cc2cnn(CC)c2)cc1 +CCCC(C)NC(=O)CNc1cccc(F)c1F +CN(C(=O)Cc1cccs1)C(C#N)c1ccc(Cl)cc1 +Cc1cc(C(C)NS(=O)(=O)c2ccc(C#N)cc2)c(C)o1 +Cc1ccc(C#CCO)cc1NC(=O)c1ccsc1 +Cn1c(COc2ccc3ccccc3c2)nnc1SCC(N)=O +C#Cc1cccc(N(Cc2ccco2)C(=O)CCN2CCCC2=O)c1 +CC(=O)N1CCOCC1c1nccc(N2CCOCC2)n1 +Cc1cc(NC(=O)CN(C)C(=O)c2ccc(C)o2)no1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2cc(Cl)ccc2C)cc1 +O=C(NCC1CCCO1)c1cnc(N2CCCC2)nc1 +Cc1cc(OCc2cc(=O)n3ccccc3n2)nnc1C +CN(C)S(=O)(=O)NC1CCCN(c2ccccc2F)C1=O +COc1ccc(CN2CC(C(=O)Nc3ccccc3O)CC2=O)cc1 +O=C(NCc1ccccc1)c1c(O)nc2ccccn2c1=O +O=C(Cc1ccc2c(c1)OCCO2)Nc1nnc(-c2ccccc2)o1 +C=CCN(Cc1cccc(OC)c1)C(=O)c1cnccc1C +CNC(=O)c1sc2ccc(NC(=O)c3ccsc3)cc2c1OC +CC(=O)Nc1ccc(Cl)c(NC(=O)Cc2ccc(F)c(F)c2)c1 +Cc1nn(C)c(C)c1NC(=O)CSc1nnc(C2CC2)n1C1CC1 +CCCC(=O)NCCNS(=O)(=O)c1ccc(C)cc1 +Cc1ccc(C(=O)NCc2cccc3cccnc23)cc1 +O=C(C1CC=CCC1)N1CCC(c2cccs2)CC1 +CC(OC(=O)CCC1CCCC1)C(=O)Nc1ccccc1F +CC(C)Oc1ccc(NC(=O)NC(CO)c2ccccc2)c(F)c1 +O=C(C1CCC1)N1CC(c2nc(-c3ccncc3)no2)C1 +CC(C)NC(=O)C(NC(=O)c1ccc2ncnn2c1)C(C)C +Cc1ccc(C(N)c2cc(-c3ccccn3)nn(C)c2=O)cc1 +Cc1cnn(-c2ccccc2)c1NC(=O)Cc1ccon1 +CC1CCc2nc(NC(=O)NCCCN3CCOCC3)sc2C1 +CCN(c1ccccc1)S(=O)(=O)c1cccc(C(=O)N(C)C)c1 +CNC(=O)C1(NC(=O)c2cc(C)n[nH]2)CCCCC1 +O=C(c1cccc(-c2ccoc2)c1)N1CCC(Nc2cccnn2)CC1 +O=S(=O)(c1ccccc1)N1CCN(CCO)CC1 +COc1ccc(-c2ccc(OCCO)cc2)cc1OC +Cc1cnc(C2NCCc3cc4cc[nH]c4cc32)cn1 +Cc1cccc(OCC(=O)NCC(C)(C)N2CC(C)OC(C)C2)c1 +CC(C)C(C)NC(=O)NC1CCc2cc(F)ccc21 +CN(C)C(=O)C1CCCN(C(=O)C2COc3ccc(F)cc3C2)C1 +Cn1cc(NC(=O)c2cccc(-c3nnnn3C)c2)cn1 +Cc1ccc(-n2cccn2)c(-c2cn(CCN3CCNC3=O)nn2)c1 +COc1ccc(CCCCC(=O)N2CCOC(C)(C)C2)cc1 +CCN(C(=O)COc1ccc(C(N)=O)cc1)c1ccccc1 +Cc1ccc(C(=O)Nc2nc3c(C)cccc3s2)c(=O)[nH]1 +CC(C)C(=O)Nc1ccccc1C(=O)N(C)C1CCCCC1 +CC(C)N(C(=O)Cn1ncc2cccn2c1=O)C(C)C +Cn1c(CCNS(=O)(=O)c2cccs2)nc2c(F)cccc21 +CC(C)CNC(=O)CN(C)c1ccc(Cl)cn1 +COC1CCCCC1OC(=O)CCC(=O)c1ccc(C)cc1 +CN(Cc1ccnn1C)C(=O)c1cc(-c2cccs2)on1 +Cn1c(SCc2cccc(F)c2)nnc1-c1cccnc1 +NC(=O)c1ccnc(NCCc2cccc(F)c2)c1 +CSc1nsc(SCC(=O)Nc2nnc(C(C)C)s2)n1 +CCOc1ccc(CCC(=O)Nc2ccc(C(N)=O)cc2)cc1N +CSc1ccc(-c2ccc(-n3ccnc3)cc2)nn1 +CC(C)(C)CC(=O)NCc1cccnc1-c1ccccc1 +CC(C)c1nn(-c2ccccc2)cc1CN1CCOC2(CCC2)C1 +CC(C)(C)NC(=O)CSc1nccn1Cc1ccccc1 +CCOC1(CCS(=O)(=O)c2ccccc2)OCCO1 +COCCn1nc(C)c(CNC(=O)c2ccc(=O)n(C)n2)c1C +O=C(CSc1nc(=O)n(CCCO)c2c1CCC2)N1CCCC1 +CC1CCCCC1NC(=O)Cn1c(=O)[nH]c2ccccc21 +COc1ccc(NC(=O)CCc2ccccc2)cc1OC +Cc1[nH]c(=NS(=O)(=O)c2cnn(C(C)C)c2)sc1C +Nc1nc(C(=O)NCc2cccc3c2OCO3)n[nH]1 +Cc1cc(C)n(C2CCN(C(=O)c3cc4c(s3)CCCC4)C2)n1 +Nc1c(-c2ccccc2)nnn1-c1ccccc1F +COC(=O)c1ccc(C(=O)N(C)CCCc2ccccc2)nc1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2nc3ccccc3[nH]2)cc1 +CN(C)C(=O)C(Sc1nnnn1Cc1ccco1)c1ccccc1 +CC1COCCN1C(=O)c1cn(C)nc1-c1ccc(F)cc1F +O=C(Nc1ccccc1-n1ncc2c(=O)[nH]cnc21)c1ccccc1 +Cc1cc(C)n(-c2ccc(Br)c(C)c2)n1 +CCSc1nnc(NCC(=O)c2ccccc2)s1 +CCC(C)NC(=O)CC1CCN(C(=O)Nc2ccccc2)CC1 +O=C(C1CCCO1)N1CCN(c2ncnc3[nH]ncc23)CC1 +Cc1ccnc(N2C3CCC2CC(N(C)C(=O)c2ccccc2)C3)n1 +Cc1nc(C(N)c2cccc(Br)c2)sc1C +CCC(C)n1ncc(C(=O)N2CCN(CC(F)F)CC2)c1C1CC1 +CCC(=O)N1CCN(Cc2ccc(F)c(-c3cccs3)c2)CC1 +O=C(NC1CCCCCC1)C1CCN(C(=O)c2ccsc2)CC1 +CS(=O)(=O)c1ccc(C(=O)Nc2ccc(-n3cncn3)cc2)cc1 +Cc1cc(N2CCC(c3nccnc3Nc3cnccn3)CC2)ncn1 +Cc1cc(Br)cc(C)c1NC(=O)NCc1ncoc1C +COCCCC1CCCN(C(=O)c2c(F)ccc(C)c2Cl)C1 +Cc1cc(C)c2nc(C)cc(C(=O)N3CCCC3c3cc(C)on3)c2c1 +Cc1noc2ncc(C(=O)N3CCOc4ccccc43)cc12 +OC(Cc1cccc(F)c1F)c1cc(F)cc(F)c1 +NS(=O)(=O)c1ccc(CC(=O)NCC2CC=CCC2)s1 +O=C(C1CCCc2[nH]ncc21)N1CC=C(c2ccccc2Cl)CC1 +CCc1noc(CC)c1CC(=O)NC1CCCC(C(=O)NC(C)C)C1 +C#CCNC(=O)CCC(=O)c1ccc2c(c1)OCCO2 +Cc1ccccc1C1CC(C)N(Cc2nc(C3CC3)no2)C1 +C=CCC1(CC=C)CCN1C(=O)c1cnc(SC)nc1 +CC(C)c1ccccc1NC(=O)c1ccccc1-n1cnnn1 +CCNC(=O)Nc1ccc(C(=O)NC2CCCC2)cc1C +CCCCN(C(=O)c1cnc(C)nc1C)C(C)CC +C#Cc1cccc(N(C(=O)CCCCOC)C(C)C)c1 +CCN(CC)C(=O)CN(C1CC1)S(=O)(=O)c1cccnc1 +O=C(CCNC(=O)c1csnn1)NC1CCCCC1 +CC(C)CCC1CCCCN1C(=O)CCn1ccccc1=O +COc1cccc(C(=O)N2CCC3CC(C)OC3C2)c1 +COc1cc(Br)c(C(O)C2CCCOC2)cc1OC +CNC(=O)NCC(=O)Nc1ccc2c(c1)nc(C)n2C +CC(O)(CN1CCOCC1)c1ccc(Br)cc1 +CC(C)N1CCOC(CCNC(=O)Nc2ccc(F)cc2)C1 +NC(=O)c1cc(N)n(Cc2ccc(F)c(Cl)c2)n1 +Cc1ccc(C(=O)NCCN2CCCCCC2=O)o1 +COCc1cc(C)nc(SCC(=O)c2ccc(F)cc2F)c1C#N +COc1ccc(S(=O)(=O)NCCc2ccoc2)cc1F +CC(O)CNS(=O)(=O)c1ccc(C(=O)C2CC2)cc1 +CC1CCN(C(=O)CN(c2ccccc2)S(=O)(=O)N(C)C)CC1 +O=C(Nc1c[nH]c2c(Cl)cccc2c1=O)N1CCOCC1 +Nc1cccc(Cn2c(C3CC3)nc3cccc(F)c32)c1 +CCNC(=O)c1cccc(NC(=O)COc2cccc(C(C)=O)c2)c1 +Cn1cccc(NC(=O)c2cc(-c3ccccc3)no2)c1=O +COc1cccc(NC(=O)NCCC(O)c2cc(C)oc2C)c1OC +O=C(Nc1cc(F)ccc1Cl)c1cn2cccnc2n1 +COC(=O)c1sccc1NC(=O)CN(C)CC(C)C#N +Cc1cc(NC(=O)C(C)OC(=O)c2ccc3c(c2)OCO3)no1 +COCCN1CCOCC12CCN(C(=O)c1cc[nH]n1)CC2 +COCCCn1cnnc1SCc1ccc(F)cc1 +CCc1ccccc1OCC(=O)N1CCN(Cc2cc(C)on2)CC1 +Oc1cc(F)c2c(c1)C(CCC1CCCCC1)NCC2 +O=C(CCc1ccc(F)cc1)N1CCC(C(=O)N2CCCCC2)C1 +N#Cc1cccc(C(=O)N2CCSc3ccc(N)cc32)c1 +CC#CCCN1CCN(S(=O)(=O)c2ccc3[nH]c(=O)[nH]c3c2)CC1 +CC1Sc2ccc(C(=O)N(C)CC(N)=O)cc2NC1=O +O=C(c1cnccn1)N1CC(S(=O)(=O)c2ccc(Cl)cc2)C1 +O=C(CCCn1ccc2cc(Cl)ccc21)NCc1ccc[nH]1 +COc1cccc(NC2CCN(C(=O)c3ccccc3)CC2)c1 +CC1(C(=O)NCc2ccc(-n3ccnc3)nc2)CCCc2ccccc21 +COC(=O)CC(c1ccc2c(c1)CCCC2)C1CC1 +CNC(=O)Cc1ccc(NC(=O)N(C)Cc2ccccn2)cc1 +N#CCCN(Cc1cccnc1)C(=O)COC1CCCCC1 +CCC1CCCCN1C(=O)c1cnn2cc(Br)cnc12 +COC(=O)CCC(=O)c1cc2c(cc1Cl)CCCC2 +O=C(NCCNC(=O)c1ccc(F)cc1F)c1ccc(O)cc1 +CCc1ccccc1NS(=O)(=O)CC12CCC(CC1=O)C2(C)C +CC(C)OC(=O)C(C)Oc1ccc2c3c(c(=O)oc2c1)CCC3 +Cn1cc(S(=O)(=O)N2CCCC2C(=O)OCc2ccccc2)cn1 +COc1ccc(C(=O)c2ccccc2C(=O)Nc2ccnn2C)cc1 +COc1ccc2c(CC(=O)NC(C)c3ccccc3)cc(=O)oc2c1 +COC(=O)CC(NC(=O)OC(C)(C)C)c1ccc(F)cc1F +C=CCOC(C)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +O=C(CN1CCCc2ccccc21)N1CCN(c2ncccn2)CC1 +CC1(C)CN(C(=O)Cn2cc(N)ccc2=O)CCO1 +C=CCCNc1cc(C(=O)NCC(F)(F)F)cc(F)c1C +CC(C)n1cc(C(=O)NCCc2ccc(O)cc2)c2ccccc21 +NC(=O)c1nn2c(C(F)(F)F)cc(-c3ccco3)nc2c1Cl +NC(=O)C1CCN(C(=O)C2c3ccccc3Oc3ccccc32)CC1 +O=C(c1ccc2c(c1)CCO2)N1CC=C(c2c[nH]c3ncccc23)CC1 +Cc1ccc(-c2nc(C(c3cccc(F)c3)N(C)C)n(CCO)n2)o1 +Cc1cc(NC(=O)COc2ccc(F)cc2)no1 +Cc1ccc2c(=O)c(C(=O)N3CCCC3)cn(CC(N)=O)c2n1 +Fc1cc(F)cc(CNc2ccc3c(c2)COC3)c1 +CCOC(=O)C(C)NC(=O)c1cc2c(OC(F)F)cccc2[nH]1 +CCS(=O)(=O)N1CCC(C(=O)c2ccccc2)CC1 +CN(C(=O)CCc1cnn(-c2ccccc2)c1)c1ccc(F)c(F)c1 +CCCC(=O)N1CCCC(C(=O)Nc2cccnc2-n2cccn2)C1 +Clc1ccc(OCc2nnc(-c3ccccn3)o2)c(Cl)c1 +CCc1nc(CNc2cc(C(=O)OC)ccc2F)no1 +Cc1nonc1CNC(=O)CCc1nc(-c2ccccc2Cl)no1 +CCNC(=O)C1CCN(C(=O)NC(C)Cc2ccc(O)cc2)CC1 +Cc1cc(CNC(=O)Nc2ccccc2C)c(C)o1 +CN(Cc1cnc2ncccn12)C(CCO)c1ccccc1 +CCC(C)CS(=O)(=O)c1ccc(S(=O)(=O)N2CCCC2)cn1 +CN(C)c1nc(CNC(=O)NCC(C)(C)c2ccncc2)cs1 +Cn1cc(C(N)c2ccc(Br)cc2C(F)(F)F)cn1 +CCCC1CN(C(=O)c2cc(Cl)ccc2Cl)CCO1 +CC1CCN(C(=O)c2cc3c(nc2N)CCC3)CC1 +Cc1ccc(OCc2nn3c(-c4cccnc4)nnc3s2)cc1 +COc1ccc(C(=O)N2CCn3cnnc3C2)c(OC)n1 +Cc1nc(CNC(=O)N2CCc3cc(F)ccc3C2)oc1C +Cc1cc(-c2nn3c(-c4ccccc4)nnc3s2)n(C)n1 +CCc1cc(CN(C)Cc2ccc(S(C)(=O)=O)cc2)on1 +N#CC(NC(=O)CCc1ncc(-c2ccccc2)o1)c1ccccc1F +COC(=O)c1ccc(=O)n(Cc2cccc(OC(C)C)c2)c1 +CCCCn1nc(C(=O)Nc2cc(C)n[nH]2)ccc1=O +COc1cccc(OC)c1CNC(=O)CC1NC(=O)c2ccccc21 +O=C1NCCN1c1cccc(C(=O)N(Cc2cccnc2)C2CC2)c1 +C=CCn1c(SCc2nc(N)c3ccccc3n2)nnc1C1CC1 +Cc1ccc(S(=O)(=O)NCCNC(=O)NC(C)C)cc1 +CC(C)(C)c1cc(NC(=O)CNc2cccc3c2OCCO3)on1 +Nc1ccc(C(=O)Nc2cccc3[nH]ncc23)cc1 +COc1cccc(Cl)c1CC(=O)N(C)CCN1CCCC1=O +COc1ccc(CN2CCC(c3nnc(-c4ccncc4)o3)C2)cc1 +Cn1cccc1-c1cc(C(=O)N2CCCC2c2nccs2)[nH]n1 +CCCCC(=O)N1CCC(c2ccsc2)CC1 +COc1ccccc1Oc1ncnc(N2CCCCC2C)c1N +CN(C)c1nc(N)nc(COc2ccc(-n3cnnn3)cc2)n1 +CN(CC1COCCO1)C(=O)Cn1c(=O)[nH]c2ccccc21 +CC(C)(C)Oc1cc(C(N)=O)ncc1OC1CC1 +CCc1nnc2n1CCN(C(=O)c1ccccc1Oc1ccccc1)C2 +CCCc1nnc(N2CCOC3(CCCC3)C2)s1 +CNC(=O)c1cccc(NC(=O)c2nonc2C)c1 +O=C(CCCc1cccs1)OCc1cc2ccccc2[nH]c1=O +CCCOc1ccc(C(=O)NCc2cccs2)cc1 +Cc1ccc(S(=O)(=O)Nc2cccc(Oc3cnccn3)c2)cc1 +Cc1noc(C)c1COc1ccc(C(=O)NC2CC2)cc1N +COc1cccc(C(=O)N2CCC2c2ccc(F)cc2)c1OC +Cc1noc(C)c1COc1cccc(NC(=O)CN2CCCC2=O)c1 +COc1ccc(N)cc1OCC(=O)NCC1CC1 +COc1cc(C)c(C(=O)NCC2Cc3ccccc3O2)cc1OC +CN(C)C(=O)c1ccccc1NC(=O)C1COc2ccc(F)cc2C1 +O=C(Nc1cccc(NC(=O)c2cccs2)c1)c1ccncc1 +Cc1ccc(C(=O)Nc2ccc3c4c(c(=O)[nH]c3c2)CCC4)cc1C +COc1ccc(CNc2ccc3[nH]nc(C(N)=O)c3c2)cc1F +Cc1n[nH]c(C)c1CCOC(=O)c1cc(C)n(C(C)C)c1C +O=C(CSc1nnc(-c2cccnc2)o1)NCCc1cccs1 +Cc1ccc(-n2ccn3c(SCC#N)nnc3c2=O)cc1C +N#CCCN(Cc1ccccn1)C(=O)C1CC12CCCc1ccccc12 +Cc1nc(C2CCCN(Cc3ccc4ncccc4c3)C2)[nH]c(=O)c1C +Cc1cc(C(F)F)nn1CC(=O)Nc1ccon1 +Cc1nccc(CNC(C)c2ccc(S(N)(=O)=O)cc2)n1 +Cc1nc(N2CCCCC2)ncc1C(=O)N1CC(C)(C)C(C)(O)C1 +CC(NC(=O)c1ccccc1)C(=O)NCc1cccc(Cl)c1 +CN(Cc1ccccc1)C(=O)C1CN(C(=O)c2ccc(F)c(F)c2)C1 +Cc1noc(C2CCN(C(=O)NC(C)c3ccc(C)c(F)c3)CC2)n1 +CCc1nc(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)c[nH]1 +CCc1cccc(NC(=O)c2ccc3c(c2)OCCO3)c1 +CCc1nc(C(=O)N(CCC#N)CCC(F)(F)F)c[nH]1 +Nc1ccc(F)cc1C(=O)Nc1ccc2nc[nH]c2c1 +CCN1C(=O)CCc2cc(NC(=O)c3ccnn3C)ccc21 +Cc1noc(CN2CCN(Cc3nc(N)c4ccccc4n3)CC2)n1 +O=C(NCc1ccc(OCC2CCCO2)cc1)c1ccc[nH]c1=O +CCc1nnc(NC(=O)NC(c2ccccc2)C(C)C(=O)OC)s1 +C#Cc1cccc(N(C(=O)C2CCN(C(=O)CCC)CC2)C(C)C)c1 +COc1ccc(-c2nc3c(F)cccn3c2C(C)O)cc1 +O=C(Cc1coc(-c2ccccc2)n1)N1CCc2cc(F)ccc2C1 +Cc1ccc(NC(=O)C(C)Sc2nncn2N)c(C)c1 +COc1ncccc1CNC(=O)NC(C)c1ccc(C)o1 +CCOc1ccc(C(=O)Nc2ccc3c(c2)OCO3)cc1 +Cc1nsc(C)c1Nc1c(C#N)nnc2ccccc12 +COCC(=O)N1CCCc2ccc(NC(=O)C3CCCC3)cc21 +CN(CCCc1cnn(C)c1)C(=O)C(N)c1ccccc1 +Cc1cc(C(O)Cc2cccs2)c2c(c1)C(C)C(=O)N2 +Cc1cccc(-c2ccc(C(=O)NCC3CCCO3)c(=O)[nH]2)c1 +Cc1cc(C(C)NC(=O)c2sccc2C)c(C)o1 +CCCNC(=O)c1ccc(=O)n(Cc2ccccc2)n1 +CCC(C)(C)NC(=O)CN(C)S(=O)(=O)c1ccc(C#N)cc1 +CC(C)N(C)C(=O)CN1CCN(C(=O)C(C)(C)c2ccccc2)CC1 +O=C(NCc1ccc(F)c(Cl)c1)c1cccc(F)c1 +CCc1nnc(SCC(=O)Nc2ccccc2)o1 +CC(C)(C)n1cc(C(=O)NC2CCCNC2=O)cn1 +Cc1ccc(F)c(NC(=O)NCCCN2CC(C)OC(C)C2)c1 +Cc1cc(N)n(-c2nc3ccccc3n2CC(C)C)n1 +Cc1cccc(N2CCN(C(=O)CCCc3nc(C)no3)CC2)c1 +CC(O)CC1CCCN1S(=O)(=O)N1CCC(C(C)(C)C)CC1 +O=C(c1ccccc1Br)N1CCCCC1 +Cn1ccnc1S(=O)(=O)CC(=O)Nc1ccc(Cl)cc1 +CCCOC(=O)c1cc(S(N)(=O)=O)ccc1N1CCOCC1 +COCc1cc(C(=O)N2CCCC(n3cnc4ccccc43)C2)no1 +CCn1nnnc1SCC(=O)c1cc(OC)ccc1OC +CCOC(=O)C(C)NS(=O)(=O)c1c(C)sc2ccccc12 +CC1CCCCC1OCC(=O)Nc1ccc(Oc2cccnc2)nc1 +COc1cccc(CNC(=O)COc2ccccc2O)c1 +Cc1nn(-c2ccccc2)c(C)c1C1C=CC(O)C1 +Cc1nc(COc2cc(Cl)cc(Cl)c2)sc1CO +FC(F)(F)COc1ccccc1OCc1noc(-c2ccoc2)n1 +CC(=O)N1CCC(NC(=O)NCCCCN(C)c2ccccc2)CC1 +CC1CCCC(C)N1C(=O)N1CCOC(C(N)=O)C1 +CC(O)(CNC(=O)Nc1nnc2ccccn12)c1ccccc1Cl +O=C1CCCc2[nH]c(=O)c(C(=O)Nc3cccc(F)c3)cc21 +CCN(CCCNC(=O)N1CCCC1)c1ccccc1 +CC(NC(=O)C1CCN(C(=O)c2ccco2)CC1)c1ccccc1 +NC(=O)C1CCCN(C(=O)CCCNC(=O)c2cccs2)C1 +COc1ccc2nc(N3CC(C(=O)NCC(C)C)C3)sc2c1 +CCOCc1nnc(NCc2csc(C)n2)o1 +COc1cccc(C(=O)Nc2cccc(NC(=O)C3CC3)c2)c1 +COC(=O)C1=C(C)C(C(=O)C(C)Sc2nnnn2C)=NC1C +NC(=O)C(c1ccccc1Cl)N1CCc2sccc2C1 +N#Cc1cccc(S(=O)(=O)N2CCN(c3ccc(F)cc3)CC2)c1 +CC(=O)Nc1ccc(NC(=O)C2CC(=O)N(Cc3ccco3)C2)cc1 +O=C1CCCc2[nH]c(=O)c(C(=O)N3CCCC3c3ccccc3)cc21 +CC(C)c1nnc2n1CCN(C(=O)C1CC(=O)N(C(C)(C)C)C1)CC2 +O=C(NCC1CN2CCCCC2CO1)Nc1nnc(C2CC2)s1 +CCc1ncc(C(=O)N(CCN2CCOCC2)c2ccccc2)s1 +CCOC(=O)c1cnc(C)nc1Nc1ccc(F)cc1 +O=C(CCN1CCCC1=O)NCC1(c2ccc(F)cc2F)CC1 +CC(=O)NCCNC(=O)c1cccc2ccccc12 +Cc1ccc(N2CCC(C(=O)NC3CCCC3)C2=O)cc1 +Cc1cc(OC(F)F)c(C(=O)NCCc2nc[nH]n2)s1 +Cc1cc(-c2nnn(CC(=O)Nc3c(C)n[nH]c3C)n2)ccc1F +O=C(CSc1nncs1)NCCCN1CCCCCC1=O +CC(CC#N)Sc1ccccc1NC(=O)c1ccc2[nH]ccc2c1 +CC(NC(=O)c1cccs1)C(=O)N1CCN(CCO)CC1 +O=C(Cc1ccc[nH]1)NC1CCN(c2cccs2)CC1 +COc1ccc(-c2nc3scc(C)n3c2N)cc1OC +CNc1nc2c(c(=O)[nH]c(=O)n2C)n1CCCc1ccccc1 +COC(=O)C(C)N(Cc1cccc(OC)c1)C1CC1 +COc1cc(C#N)ccc1OC(=O)CCSc1ccc(F)cc1 +CN(C)c1ccc(C(=O)NCC(O)c2ccc(F)c(F)c2)cc1 +O=C(NC1CC1)c1ccc(Oc2nccnc2N2CCCCC2)cc1 +Cn1cc(S(=O)(=O)N2CCCN(c3ccccc3C#N)CC2)cn1 +CCNC(=O)CNc1cccc(Cl)c1N1CCOCC1 +COCCNc1nc2cc(Cl)c(C)cc2s1 +N#Cc1ccc(Cl)cc1NC(=O)COC(=O)c1ccc(O)cc1 +CC1CCCC(C)N1S(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +Cc1noc(COc2ccc(OC(=O)C(C)(C)C)cc2)n1 +Cc1cc(N)ccc1NC(=O)C(C)OCc1ccco1 +Cc1noc(C)c1CCC(=O)NCCNC(=O)C(C)C +CCc1cnc(CN(C)C(=O)Nc2cccc(C(=O)N(C)C)c2)s1 +COc1ccc(-c2c(N)n[nH]c2-c2ccc(F)cc2)cc1OC +Cc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1Cl +CNC(=O)c1cccc(OC(=O)c2cnc(C)cn2)c1 +CCn1c(-c2ccccc2)nc2c1c(=O)[nH]c(=O)n2Cc1ccccc1 +CC1=C(C(=O)NCCSc2ncn[nH]2)C(C)NC(=O)N1 +CC(C)n1ncc2cc(C(=O)NCCCNS(C)(=O)=O)cnc21 +CCCCNC(=O)C1CCC(C)N(Cc2scnc2C)C1 +Cc1cccc2c(=O)n(CCC(=O)N3CCOCC3C3CC3)cnc12 +O=C(Nc1cnn(C2CCOCC2)c1)C1CCOC1 +Cc1noc(C)c1Cc1nnc2sc(-c3ccc(F)cc3)nn12 +Cn1ccc(C(=O)NCC2CCN(c3ccc(Cl)cc3)C2)cc1=O +COc1cc2c(cc1C)CCNC2c1cncn1C +Cc1ccc(C(C)C)cc1Oc1c(C#N)c(=O)n(C)c(=O)n1C +COc1cccc(CNc2nccn(-c3ccc(F)cc3)c2=O)c1 +COc1ccc(OC)c(CN(C)C(=O)c2ccco2)c1 +Cc1ccccc1C(=O)Nc1cccc(-n2cnnc2)c1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(F)nc1 +O=C(CNC(=O)c1ccc(F)c(F)c1)Nc1ccncc1 +CCc1cc2c(NCC(O)c3ccccc3)nc(C)nc2s1 +COc1ccc(-c2cc(C(=O)NCc3ccccc3)on2)cc1 +CCN(C)C(C(=O)N1CCC(c2noc(C)n2)CC1)c1ccccc1 +CC(=O)N(C)CC(=O)NCCCOC1CCCc2ccccc21 +Cc1cc(S(=O)(=O)NCCNC(C)c2cnccn2)c(C)s1 +O=C(c1cc(C2CC2)n[nH]1)N1CCC(Oc2ccc(Cl)cc2)CC1 +NS(=O)(=O)c1ccc(CNC(=O)c2cnc(C3CC3)[nH]c2=O)cc1 +CN(Cc1cnn(-c2ccccc2)c1)C(=O)CCC(C)(C)C +CNC(=O)Cn1nnc(CO)c1COc1cc(C)ccc1C +CCN1CC(C(=O)N(C)CC(O)COC)CC1=O +O=C(Cc1cc(Cl)cc2c1OCOC2)Nc1ccccc1 +c1coc(-c2nn3c(COc4ccc5c(c4)OCO5)nnc3s2)c1 +COc1ccccc1NS(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +CCS(=O)(=O)c1nnc2ccc(C(F)(F)F)cn12 +COCCN1CCOC2CCN(c3cnccn3)CCC21 +CC(C#N)CC(=O)N1CCN(c2ccccc2)CC1 +CCCc1ccc(C(=O)N2CCCC(c3cc(C(N)=O)[nH]n3)C2)cc1 +CCCCn1c(SC(C)C(=O)Nc2ccc(F)cc2)n[nH]c1=O +CCCCN(C)C(=O)c1cnc(SC)n1-c1ccc(F)cc1 +N#Cc1cccc(C(=O)Nc2nc(CC(N)=O)cs2)c1 +COc1ccc(OC)c(CCNC(=O)c2c[nH]c3cc(F)ccc23)c1 +CC(=O)N1CCC(c2cnn(-c3cccc(C)c3)c2)CC1 +COC(=O)C(C)NC(=O)c1[nH]c(C)c(C(C)=O)c1C +CCN(CC(=O)OC)C(=O)c1c(C)cccc1N +COc1ccccc1C1CC1C(=O)N1CCN(CC(=O)N(C)C)CC1 +Cc1cccc2c1NC(c1ccccc1OCC1CC1)NC2=O +Cc1ccc(OCCC(=O)N2CCC(C(N)=O)CC2)cc1C +COc1cc(CO)cc2c1OC(C)C(=O)N2CC(O)CO +O=c1c2nnc3c(-c4ccccc4)cnn3c2ncn1CCO +Cc1cc(NC(=O)c2ccc(-c3ccccc3F)o2)no1 +N#CCCCS(=O)(=O)N1CCCC1c1ccco1 +CCCc1[nH]ncc1C(=O)NCC1COc2ccccc2O1 +CC1CCN(C(=O)c2ccc3[nH]nnc3c2)C2CCCCC12 +COc1ccc(C(=O)N2CCN(c3ccc(C)cc3C)CC2)cc1F +Cc1c(C)n(-c2ccc(F)cc2)c2ncnc(N)c12 +COc1ccc(F)c(C2NC(=O)CCC2NCc2cccnc2)c1 +CC(=O)c1c(C)[nH]c(C(=O)NCCOc2cccnc2)c1C +O=C(Nc1ccc2nc[nH]c(=O)c2c1)c1ccc(Cn2cccc2)cc1 +O=C(CCn1c(=O)oc2ccccc21)Nc1ccccn1 +Nc1cc(Cl)ccc1S(=O)(=O)N1CCCCC1 +O=c1[nH]c(N2CCN(Cc3ccccc3)CC2)nc2c1CCCC2 +Cc1noc(CCCC(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)n1 +O=C(Nc1ccc(Cl)cn1)c1cc2ccccc2oc1=O +CN(Cc1ccncc1)C(=O)c1ccc(Cl)cc1O +CC(C)(C)n1nccc1NC(=O)C1CC1c1ccccc1 +c1cncc(C2NC3c4c(ccc5ccccc45)OCC3CO2)c1 +CCCCN(C)C(=O)CCC(=O)c1ccc2c(c1)CCC2 +CCC(C)NC(=O)C(C)NC(=O)Nc1cnn(-c2ccccc2)c1 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(N(C)C)cc1 +COc1ccc(CCC(=O)Nc2cccnc2-n2ccnc2C)cc1 +Cc1cc(C)cc(C(=O)Nc2nnc(-c3sc(C)nc3C)o2)c1 +CCn1cnnc1CNC(=O)NCc1cnn(C)c1 +CCc1ccc(N2CC(C(=O)NC3CCCCC3)CC2=O)cc1 +COC(=O)Cc1ccc(NC(=O)c2ccc(NC(C)=O)cc2)cc1 +Cn1cc2c(n1)C1CN(C(=O)c3cc(C(F)(F)F)nn3C)CC1C2 +O=C(NCC1CCCO1)Nc1ccc(OCCc2ccccn2)cc1 +COc1ccc(C(C)N(C)C(=O)NCCNC(=O)c2ccco2)cc1 +COC1C(C)C(Nc2cc(-c3ccccc3)nc3ncnn23)C1(C)C +CCn1ccc(NC(=O)Nc2ccccc2C(F)(F)F)n1 +O=C(Nc1nc2c(s1)C(=O)CCC2)c1ccccc1Cl +CCc1nc2c(NC(=O)Cc3ccc(Cl)cc3)cccn2n1 +Cc1ccsc1C(=O)N(C)C1CCN(C(=O)OC(C)(C)C)CC1 +Cc1noc(C)c1CNc1nnc(Cc2ccc3ccccc3c2)o1 +COc1c(N)cc(-c2nc3ccccc3s2)cc1N +COc1cccc(-c2cn3ccn(-c4ccccc4)c(=O)c3n2)c1 +Cc1cccc(Cl)c1NC(=O)c1cc(=O)[nH]c2ccccc12 +CC(C(=O)NC1CCCCC1)n1ncn2c(cc3occc32)c1=O +CCn1c(SCC2CCCO2)nc2cc(S(N)(=O)=O)ccc21 +Cc1cc(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)n(C)n1 +Cc1ccc2oc(NCCn3c(C)nc4ccccc43)nc2c1 +CCOc1cc(N2CCN(S(C)(=O)=O)CC2)nc(C)n1 +CC(C)c1nnc(NC(=O)CN(C)C(=O)C(C)n2cccn2)s1 +Cc1nn(C)c(C)c1NS(=O)(=O)c1c(Cl)cccc1Cl +COCCn1ccc2cc(C(=O)Nc3nncs3)ccc21 +O=C(CCC(=O)Nc1nccs1)Nc1ccc(Cl)c(F)c1 +NC(=O)CSc1c(-c2ccccc2)[nH]c2ccccc12 +O=C(NCc1ccc(F)cc1)NCC1(c2cccs2)CCOCC1 +COc1ccc(NS(=O)(=O)c2ccc(F)cc2)cc1O +Cn1nccc1C(=O)N1CCC(n2cc(-c3ccsc3)nn2)CC1 +Cc1ccc(C(C)NC(=O)c2ccc(C(N)=O)nc2)cc1F +O=C(CSc1ncnc2sccc12)NCCc1cccs1 +CC(O)c1cccc(NC(=O)Cc2ccccc2)c1 +Cc1ccc(NC(=O)c2cccc3ccc(C)nc23)c(F)c1 +CC(=O)Nc1ccc(NCc2ccc(C)cc2)cc1 +CN(Cc1ncnn1C)C(=O)NCC1(Sc2ccccc2)CC1 +COc1ccnc(N2CCN(CC(C)(C)N3CCOCC3)CC2)n1 +N#CCCN(Cc1ccccn1)Cc1c(F)cccc1N1CCCC1 +CNS(=O)(=O)c1ccc(C(=O)NC(C#N)c2ccccc2F)cc1 +CN(Cc1ccccc1F)S(=O)(=O)c1ccccc1Cl +CCC(=O)N1Cc2nn(-c3ccc(C)c(C)c3)c(-n3cccc3)c2C1 +O=C(NCC1Cc2ccccc2O1)NC1CCCCNC1=O +COCCn1c(SCC(N)=O)nnc1-c1ccccc1 +CC(NC(=O)c1cccc(N(C)C)c1)c1ccccc1 +CC(c1cc(F)ccc1F)N(C)C(=O)c1ccccc1F +CCOC(=O)c1cc(C(=O)Nc2ccccc2)c(=O)[nH]c1C +O=C(c1cc(Oc2ccccc2)ccn1)N1CCCCC1CCO +COC(C)(C)CNC(=O)c1cnc2ccc(C)cn12 +Cc1c(CC(=O)N2CCN(CCO)CC2)c(=O)oc2cc(O)ccc12 +Cc1ccc(-c2nc3sc(=Cc4ccco4)c(=O)n3n2)cc1 +O=C(NCc1ccccc1F)c1nn2ccccc2c1Cl +CNC(=O)CC1CCN(C(=O)NCC2(c3ccccc3F)CC2)CC1 +CCn1nnc(NC(=O)c2ccc(OCC(C)C)cc2)n1 +CCc1cc(NC(=O)NCC(O)c2c(F)cccc2F)n(C)n1 +CCN(C)C(=O)c1cc(C(C)C)nc2onc(C)c12 +O=C(Nc1cccc(C(F)(F)F)c1)c1csnn1 +O=C(CNC(=O)c1ccccc1F)OCC(=O)C1=NC=CC1 +CCc1c(C)cc(C(=O)N2CCC(C)(O)C(CC)C2)c(=O)n1C +O=C(Nc1ccc(Oc2cccnc2)nc1)N1CC2CCCC2C1 +CCCCOC(=O)Cn1c(-c2ccccn2)ccc(C#N)c1=O +CC(=O)c1c(C)[nH]c(C(=O)C(C)Sc2ccccn2)c1C +CCN(CCO)C(=O)Cc1noc2c(N)cc(C)cc12 +O=C(Cc1ccccc1Cl)Nc1cnc(N2CCOCC2)nc1 +CC(=O)NC(C)C(=O)Nc1nc(-c2ccccc2)ns1 +CCCS(=O)(=O)c1ccccc1C(=O)N1CCCCC1CC +CSc1ccc(CNC(=O)NCC(C)C)cc1 +Cc1ccc2[nH]c(CNCCSc3nncn3C)cc(=O)c2c1 +O=C(Nc1ccc(F)c(Cl)c1)Nc1cc(N2CCCC2)ncn1 +Cc1cc(NC(=O)C2CC(=O)N(c3cccc4ccccc34)C2)no1 +COc1cccc(-c2c(C#N)c(N)nc3c2c(=O)nc2sccn23)c1 +CC(C)(C)NC(=O)CCC(C#N)c1ccc2c(c1)OCO2 +O=C(NC1C2CCC(C2)C1CO)c1nc2ccccc2[nH]1 +COc1cccc(-c2nnn(CC(O)COc3ccc(F)cc3)n2)c1 +CCOC1CCN(C(=O)c2c(C)[nH]c3ccccc23)CC1 +Cc1occc1C(=O)N1CCN(S(=O)(=O)c2cccs2)CC1 +Cc1cc(C(=O)N2CCC3COC(CNS(C)(=O)=O)C3C2)no1 +CCOc1c(Cl)cccc1NC(=O)Cc1csc(C)n1 +CC(C)(CO)n1c(-c2ccncc2)nc2cccnc21 +CC(Sc1nnc(Nc2ccccc2)s1)C(=O)N(C)CCC#N +CC(C)n1cc(CNC(=O)CCc2c[nH]c3ccccc23)cn1 +O=C(CCCNC(=O)C1CC1)Nc1cccnc1N1CCCCC1 +CC(C)c1cc(C(=O)N2CCCN(c3ncccc3C#N)CC2)n[nH]1 +Cc1cc(C2CCN(C(=O)C(C)Oc3ccccc3)CC2)[nH]n1 +CC(=O)c1ccccc1C(=O)NCCNC(=O)c1cccc(C)c1 +Cn1cc(CCNC(=O)C2CCC2)c2cccnc21 +COc1ccc(C(C)=O)cc1CC(=O)NCCc1ccco1 +CC1(C)CN(C(=O)C2CC2)c2c(N)cc(Cl)cc21 +Cc1ccc(C(=O)N2CCc3ncnc(-c4cccnc4)c3CC2)cc1 +COc1ccc(NC(=O)c2ccnn2C)cc1OC(C)C +CC(C)C(NC(=O)Nc1ccccc1)C(=O)N1CCN(C)CC1 +CCn1cc(Cl)c(-c2nnc(-c3ccc(OC)c(OC)c3)o2)n1 +NC(=O)C1CCN(C(=O)c2ccccc2OC(F)F)C1 +CS(=O)(=O)N1CCC2(CC1)CN(c1cccnc1)C(=O)CO2 +OCCNc1nc2ccccc2n1Cc1cccc(Cl)c1 +CC1CCN(c2ncnc(NCc3cccnc3)c2N)CC1 +Cc1cc(OC(C)C(=O)N2CCNCC2)ccc1Cl +COc1ccc(N)c(NC(=O)c2cccc(Cl)c2)c1 +CC(=O)NC(CC(=O)NCc1ccccc1Cl)c1ccccc1 +Cc1ccccc1OCCCN(C)C(=O)C1(C#N)CCCC1 +CSc1nc(CSc2ccc(C)cc2)nc(N)c1C#N +COCCn1cc(NC(=O)c2ccc(C(=O)N(C)C)cc2)cn1 +CC(C)CNC(=O)CSc1nnc(-c2ccccc2Cl)n1C +CN(Cc1cccc(-n2cccn2)c1)C(=O)CN1CCOC1=O +O=C(NCc1cscn1)N1CCc2ccc(Cl)cc2C1 +CCOC(=O)C(C)Sc1nnc(NC(=O)C2CC2)s1 +CC(C)NC(=O)CCNC(=O)Nc1ccc(Cn2cccn2)cc1 +CC(=O)Nc1ccc(Cc2nc(-c3ccccn3)no2)cc1 +CN(CCCOc1ccccc1)C(=O)Nc1cn[nH]c1 +N#CCOc1cc(C(=O)NC2CCCC2)ccc1N +CC(C)CN(C(=O)NCC(C)N1CCOCC1)C1CC1 +CCc1ccc(NC(=O)NCCNC(=O)c2nonc2N)cc1 +CC(CNC(=O)Nc1cnn(-c2ccccc2F)c1)N1CCOCC1 +CC(C)Cc1nnc(NC(=O)Cc2ccc3c(c2)OCCO3)s1 +CNC(=O)c1ccc(Cl)c(NC(=O)NC2CCCC2)c1 +COCC(=O)NCC1CC(=O)N(c2ccc3c(c2)OCO3)C1 +COCCNC(=O)Cc1ccc(NC(=O)c2cccc(F)c2)cc1 +CCOCC(=O)Nc1ccnc(C(=O)N(C)C)c1 +C=CCNC(=O)c1nnc(N2CCCCC2C)c2ccccc12 +O=C(c1ccccc1)N1CCN(Cc2ccc(CO)o2)CC1 +Cc1ccncc1NCc1ccc(OC(C)C)cc1 +CCn1ccc(C(=O)Nc2nc3c(C)cc(Cl)cc3s2)n1 +CC(C#N)CN(C)C(=O)C(C)NC(=O)c1cccs1 +Cc1nn2c(=O)c3c(cc(C)n3Cc3ccc(F)cc3)nc2s1 +CC(CNC(=O)c1cc(Br)c[nH]1)CN1CCOCC1 +CCOCC1CN(Cc2ccco2)Cc2cn(CC3CCCC3)nc21 +CC1(C)CN(C(=O)CCNC(=O)c2ccc(F)cc2F)CCO1 +CCNC(=O)CN1CCN(C(=O)NC2CCC(O)CC2)CC1 +CCCCOc1cccc(NC(C)C(=O)N2CCN(C(C)=O)CC2)c1 +CCC(C)OCC(=O)Nc1cccc(-c2cn[nH]c2)c1 +CCOC(=O)c1cnc2c(Br)c[nH]c2c1 +CNC(=O)C1CCCCN1C(=O)c1cccc(Cl)c1 +COc1ccc(NS(=O)(=O)c2cccc(C(=O)N(C)C)c2)cc1 +Cc1cc(C)n(-c2ccc(C(=O)N(C)C(C)CC#N)cn2)n1 +CC(=O)NCCNC(=O)CCOc1cccc(Br)c1 +O=C(CN1CCCCC1=O)NCc1ccsc1 +O=C1NCCN1CCNc1nccc(CCC(F)(F)F)n1 +O=C(c1ccco1)N1CCN(C(=O)C2(c3ccccc3)CCC2)CC1 +CCc1oc2ccccc2c1CN(C)c1nc2c(cnn2C)c(=O)[nH]1 +CCN1C(=O)Cc2cc(NC(=O)COc3ccccc3OC)ccc21 +Cc1cc2c(=O)n(CC(=O)Nc3cccc(Cl)c3C)cnc2s1 +COc1cc(CNC(=O)COC2CCCC2)ccc1O +CCC(C)(C)NC(=O)Cn1c(-c2ccccn2)noc1=O +CCNC(C)(C#N)CN1CCC(N2CCOCC2)C1 +COC(=O)NCC(=O)Nc1cc(C(=O)OC)ccc1C +Cn1ccnc(NC(=O)Cc2ccccc2OC(F)F)c1=O +CCc1nc(CC(=O)Oc2cccc(NC(=O)C3CC3)c2)cs1 +CCOc1ccc(F)c(C(=O)Nc2cccc3c2OCCO3)c1F +CCC1Oc2ccc(N)nc2N(CC(N)=O)C1=O +CC(=O)NC(C(=O)Nc1nn(-c2ccccc2Cl)cc1C)C(C)C +O=C(Nc1cccc(O)c1)c1cc2n(n1)CCCO2 +CCn1c(N)nc2cc(C(=O)NCc3cn4cc(C)ccc4n3)cnc21 +O=C(c1coc(COc2cccc(C(F)(F)F)c2)n1)N1CC(O)C1 +CCCCNC(=O)Cc1nc2sc(-c3ccccc3)cc2c(=O)[nH]1 +O=C(NCC1CCOC1)c1ccc2ccccc2n1 +O=C(CCn1ncc2c(Cl)cccc21)NCc1cccnc1 +CCNC(=O)CSc1nc(-c2ccco2)nc2ccccc12 +CC1CC(C)CN(C(=O)CN(CCC#N)CCC(F)(F)F)C1 +CC(=O)N1CCOC(CNc2nccc(-c3cccnc3)n2)C1 +CCn1cc(CN(C)C(=O)Nc2cccc3ccccc23)cn1 +CCOC(=O)c1c(NC(=O)CC)sc(C(=O)N2CCCC2)c1C +CC(C)(C)C(=O)N1CCN(C(=O)c2n[nH]c(=O)c3ccccc23)CC1 +Cc1sc(NC(=O)C(C)C)nc1-c1ccc2c(c1)NC(=O)CO2 +CC(C)C(=O)N1CC2N(C)C(=O)c3ccccc3C(=O)C2(C)C1 +O=C(CC1CCCO1)NCc1ccc(Cn2cnc3ccccc32)cc1 +CCC=CCOC(=O)Cn1cnc2c(oc3ccccc32)c1=O +COc1ccccc1OCc1cc(C(=O)NC2(CO)CCCC2)n[nH]1 +O=C(NC1(C(=O)NCC2CC2)CCCC1)C1CC1c1ccc(F)cc1 +COc1cc(OC)nc(-c2ccc(Cl)cc2)n1 +COc1ccc(-c2nc(CNc3ccc(C)cc3)n[nH]2)cc1 +NS(=O)(=O)c1ccc(CNS(=O)(=O)c2cn[nH]c2)cc1 +Cc1cc(=O)n(CC(=O)Nc2ccc(Cl)cc2Cl)cn1 +Cc1c(C(=O)N2CCCCC2)sc2ncnc(NC3CC3)c12 +Cc1cc(F)cc2c1N(C(=O)CCNC(=O)C1CCCCC1)CCC2 +CCOC(=O)Nc1cccc(NC(=O)c2ccncc2F)c1C +CC(C)C(C)NC(=O)N1CCN(C(=O)c2cccc(Cl)c2)CC1 +COCCNC(=O)c1ccc(NC(=O)C2CCCC2)cc1 +Cc1cc(NC(=O)C2COc3ccccc3O2)ccc1C(=O)N(C)C +COc1cc(O)ccc1CNc1cccc(C)c1C +O=C(C1CC2CCN(c3cccc(F)c3)CC2O1)N1CCCC1 +O=C1CCN(C(=O)c2ccc(COc3ccccc3)cc2)CC1 +O=C(c1ccccc1)N1CC(F)C(OCc2nc3ccccc3[nH]2)C1 +Cc1nn(C)c2sc(C(=O)N(C)Cc3cccc(C#N)c3)cc12 +CCOc1c(Cl)cccc1NC(=O)NC(C)C +Cc1ccnc(SC(C)C(=O)Nc2nc3ccccc3s2)n1 +CC(NC(=O)COC(=O)C1CCCO1)c1cc2ccccc2o1 +CCOc1ccc(CN(C)C(=O)c2cc(C)oc2C)cc1 +CC(=O)c1ccc(N2CCN(C(=O)c3n[nH]c4ccccc34)CC2)cc1 +COc1ccc(C(=O)N(C)C(C)c2cc(F)ccc2F)nn1 +CC(C)CCNC(=O)c1ccc(-c2csc(C3CC3)n2)cc1 +Cc1ncc(C(=O)N(C)Cc2nc3ccccc3s2)c(C(C)C)n1 +Cn1c(-c2ccc3c(c2)OCCO3)cn2c3ccc(N)cc3nc12 +CN(CCCOc1ccc(Cl)cc1)C(=O)NCc1cccnc1 +CC(=O)c1c(C)[nH]c(C(=O)N=c2[nH]nc3cc(C)ccn23)c1C +CN(C(=O)Cc1ccc(NC(=O)C2CCC2)cc1)c1ccccc1 +Cc1ccc(C(=O)N(Cc2ccsc2)C2CC2)c(=O)[nH]1 +COC(=O)c1cccc(OCC(=O)Nc2cccc(SC)c2)c1 +CC1CN(C(=O)NC(C)c2cccnc2)CC(c2ccsc2)O1 +Cc1ccc2c(c1)OCC(=O)N2Cc1nc(-c2cccnc2)no1 +Cc1ccc(CC(=O)NCc2ccsc2)s1 +COc1ccc(C2CC2C(=O)N2CC(C(N)=O)CCC2C)cc1 +O=C(CCN1C(=O)CCc2ccccc21)Oc1cccc(F)c1F +CC(=O)c1cc(C(=O)Nc2cccc(N3CCCCC3)c2)n(C)c1 +CC(=O)N1CC(NC(=O)COc2ccc3c(c2)OCO3)C(C2CC2)C1 +O=C(CC1CC2CCC1C2)NCCCN1CCCCCC1=O +CCNC(=O)C1CCCN(C(=O)NCCCc2cn[nH]c2C)C1 +Cc1nc(CSc2nnnn2C2CC2)oc1C +CC(=O)N(C)c1ccc(NCC(=O)N2CCCCC2)cc1 +NS(=O)(=O)c1ccccc1CN1CCCCC1=O +CCCCC(NC(N)=O)C(=O)N(C)Cc1ccccc1C +Cc1ccc(C(=O)N2CCC(C(O)c3ccccc3)CC2)cc1 +CC(C)NC(=O)c1nsc(C(=O)NCC2CC2)c1N +O=C(C1CC(=O)N(c2ccc(F)c(Cl)c2)C1)N1CCCC1 +CN1CCCN(C(=O)C2CC2)c2nc3ccccc3nc21 +CN(Cc1ccccc1)C(=O)CN(C)c1ccc(F)cc1 +COc1ncccc1-c1nc(N(C)C)nc2c1CCCC2 +CN(C(=O)Cn1nc2ccccn2c1=O)C1(C#N)CCCCC1 +Cc1ccc(Br)cc1N1CCC(C(=O)NC2CC2)C1=O +COc1ccc(C2CCCN2C(=O)Cn2cc(C)cn2)cc1 +CC(OCC(F)(F)F)C(=O)NCc1ccc(O)cc1 +CC(C)c1nc2ccc(C(F)(F)F)cn2c1C(C)O +Cn1cnc(CNS(=O)(=O)c2ccc(C#N)cc2)n1 +CCS(=O)(=O)NCc1cccc(OC)c1OC +NC(=O)Cc1csc(NC(=O)c2cncn2-c2ccccc2)n1 +Cc1ncc(CNC(=O)CCn2cncn2)s1 +CCn1c(SCC(C#N)CCC#N)nc2ccccc2c1=O +Cc1cccc(OC(C)C(=O)N(C)C2(C#N)CCC2)c1 +CCCN1CCN(C(=O)Cn2nnc3ccccc3c2=O)CC1 +COc1cccc(CC(=O)N2CCC(Cn3cccn3)CC2)c1 +COc1ccc(OC)c(CN(C)C(=O)CC2C=CCC2)c1 +CNC(=O)c1ccc(NC(=O)c2cccc(Oc3ccncc3)c2)cc1 +Cc1noc(C)c1CN1CCC(OCC2CC2)C1Cc1cccnc1 +O=C(CCO)N1CCN(C(=O)c2ccc3c(c2)OCO3)CC1 +COCc1cc(C(=O)Nc2cc(F)c(F)c(F)c2)ccc1F +Cc1ncc(CN(C)C(=O)c2ccc(N3CCCC3)c(F)c2)s1 +COc1cccc(C(=O)Nc2c(C)nc3sccn3c2=O)c1 +COC(=O)Nc1cccc(NC2CCOCC2)c1 +CS(=O)(=O)N1CCCC(c2nc(-c3ccc(C#N)cn3)no2)C1 +CCN1C(=O)Cc2cc(NC(=O)c3ccco3)ccc21 +CC(Sc1ccccn1)C(=O)N1CCC(C(=O)N(C)C(C)C)CC1 +O=C(Cn1nnc(-c2ccccc2)n1)Nc1ccccn1 +Cc1ccc(C(=O)NCc2csc(=O)[nH]2)cc1Oc1ccncc1 +Cc1c(C)n(C(C)c2cccs2)c2ncnc(N)c12 +CC(C)(O)CCc1ccc(C(=O)N2CCCOCC2)cc1 +COC(=O)c1c(NC(=O)CSc2ccccn2)sc(C)c1C +COc1cc(C)c(C(=O)NCC(C)(C)c2ccncc2)cc1OC +CCCc1nnc(N(C)Cc2ccc(OC)c(OC)c2)o1 +Cc1cc(C)n(CCNC(=O)c2nn3ccccc3c2Cl)n1 +CCOc1ccc(CCNC(N)=O)cc1OCC +O=C1CCCN1C1CCN2CCCc3cccc1c32 +CN(C)C(C(=O)N1CCN(CC(F)(F)F)CC1)c1ccccc1F +O=C(CCCc1ccccc1)N1CC2C3CCC(O3)C2C1 +Cc1cc[nH]c(=NS(=O)(=O)c2ccc(F)c3ncccc23)c1 +Cc1nc2ccc(NC(=O)CC3C=CCC3)cc2o1 +Cc1noc(C)c1COC(=O)CNC(=O)c1ccc(F)cc1F +O=C(Nc1ccc(F)cc1OCC(F)(F)F)c1cccnc1 +c1ccc(C2(CNCc3cnc(N4CCOCC4)nc3)CCC2)cc1 +CCCN(C)S(=O)(=O)c1cc2c(cc1F)NC(=O)CC2 +N#Cc1c(Cl)cccc1S(=O)(=O)N1CCC(CC(N)=O)CC1 +CCN(CC(=O)NC(C)C)C(=O)c1cccc(C#N)c1 +NC(=O)NC(NC(N)=O)c1ccc2c(c1)OCO2 +CC1(c2ccccc2)CCC(=O)N(Cc2nc3ccc(F)cc3[nH]2)C1 +CC(c1cccs1)N(C)Cc1nnc(-c2cccs2)o1 +CN(C)c1cccc(S(=O)(=O)NC(C)(C)C)c1 +N#CC(NC1CCCC1)c1cc(Cl)c2c(c1)OCCO2 +O=C(CCn1ccccc1=O)Nc1ccc(Cl)cc1Cl +Cn1c(=O)cnn(-c2cc3c(cc2F)OCC(=O)N3CC2CC2)c1=O +Cc1ccc(OC(=O)C2CC(=O)N(C(C)C)C2)cc1C +Cc1nc(CN2CCOCC2CC(=O)NC(C)(CO)CO)co1 +Cc1nn(-c2ccccc2)c(C)c1CCC(=O)N1CCOC(C)C1 +O=C(c1cnc(C2CCCO2)s1)N1CCSc2ccccc2C1 +CCc1ccc(C(C)NCC(=O)N2CCCC2)cc1 +COc1ccc(N2CCN(C(=O)c3cc4ccccc4o3)CC2)nn1 +Cc1cc(Br)cc2c1OC(C)CC(=O)N2 +O=C(Nc1ccccc1)Nc1ccc(CN2CCOCC2)cc1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)NCc1ncoc1C +CCCn1cc(NCc2cc(Cl)ccc2OC)ccc1=O +Cn1cc(CNC(=O)c2cc(Cl)cn2C)cn1 +CCOCCSc1nnc(-c2cccs2)n1C1CC1 +CC1(C)CN(C(=O)C2(c3cccc(Cl)c3)CCOCC2)CCO1 +Cc1ccc(C(=O)NCC2CN3CCCC3CO2)cc1 +CC1CC1c1ccc(CCC(=O)N2CCCC(N3CCNC3=O)C2)o1 +O=c1cc(CSc2ccccc2)[nH]c2ccccc12 +Cc1noc(C)c1COc1ccccc1C(=O)N1CCC(C)(O)C1 +N#Cc1ccccc1CN1CCN(C(=O)c2ccccc2F)CC1 +CNC(=O)CNC(=O)c1c[nH]cc1-c1ccccc1 +COc1ccc(C(C)N(C)C(=O)CNC(=O)c2cccs2)cc1 +CC1Oc2ccc(S(=O)(=O)NC(C)c3ccncc3)cc2NC1=O +FC(F)(F)Oc1cccc2c1C(c1ccc[nH]1)NCC2 +Cc1[nH]c(=O)c(C(=O)Nc2cccc(C#N)c2)c(C)c1N +CCCc1n[nH]c(SCC(=O)N2CCCC3CCCCC32)n1 +Cc1ccc(C(C)(C)C)cc1C(O)CCCC(N)=O +Cc1cc(C(=O)NCCC(O)c2ccoc2)no1 +O=C(Cc1ccccc1)c1ccccc1C(=O)N1CCOCC1 +COCCSc1ccc(C(C)NC(=O)c2ccncc2F)cc1 +CCOC(=O)c1noc2ncnc(N3CCC(C)CC3)c12 +CCCc1nnc(NC(=O)c2cc3ccccn3n2)s1 +CC(C)(C)OC(=O)N1CCC(c2ccc(N)cn2)CC1 +Cn1nc(CNS(=O)(=O)C2CC2)cc1-c1ccco1 +COC(=O)c1occc1COc1ccc(C(N)=O)cc1 +CC(C)CCn1c(SCC(=O)NC2CC2)nc2ccccc2c1=O +Cc1cccc(C)c1NC(=O)CNC(=O)NCC(C)C +CCn1nc(C)c(CN2CCOC(c3cnn(C)c3)C2)c1C +CCN(CC)C(=O)COc1cccc(NC(=O)C2(O)CCCC2)c1 +CC(C)(C)c1csc(NC(=O)c2ccncc2)n1 +CCC(C)NC(=O)NCc1c(OC)cc(OC)cc1OC +CC1CN(C(=O)c2ccncc2)CCN1C(=O)c1ccncc1 +COC(=O)CCc1csc(COc2cccc(Cl)c2)n1 +Cc1ccc(N2CC(NC(=O)Nc3ccncc3)CC2=O)cc1C +CCCn1nc(-c2ccco2)cc1C(=O)Nc1ccc(F)cc1 +Cn1cc(NC(=O)C(C)(C)c2ccccc2)cc(Br)c1=O +CCNC(=O)CNC(=O)Nc1ccc2sc(C(=O)OCC)cc2c1 +CC(NC(=O)N1CCc2sccc2C1)c1ccncc1 +CS(=O)(=O)N1CCCCC1CCNc1ccncn1 +COC(=O)c1ccc(C(=O)Nc2cccnc2-n2ccnc2C)cc1 +N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)C2CCCC2)CC1 +O=C(Cn1ccccc1=O)N1CCCCCC1c1ccco1 +O=C(COc1ccccc1F)Nc1cccc(-c2ccn[nH]2)c1 +CCN(C(=O)c1cc(OC)c(OC)cc1C)c1nc(C)cs1 +CCn1c(SCC(=O)c2[nH]c(C)c(C(C)=O)c2C)nnc1C1CC1 +CC(=O)N(C)Cc1cccc(NCc2csc3ccccc23)c1 +CC(C)Sc1ccccc1C(=O)NCc1ncn(C)n1 +Cc1nc2ccc(COC(=O)CNC3CC3)cc2o1 +CC(C)C1(O)CN(C(=O)CCc2ccsc2)CC1C +O=S(=O)(Cc1nc2ccccc2s1)c1nccs1 +COC(=O)c1ccccc1NC(=O)COC(=O)c1cccc(C)c1N +Cc1ccc(S(=O)(=O)Nc2ccccc2)cc1C(=O)N1CCCC1 +CCSc1nnc(NC(=O)Cc2ccccc2Cl)s1 +CC(=O)N1CCCC1C(=O)c1cnn(-c2cccc(F)c2)c1N +CC1CCCCN1C(=O)c1cc(C(N)=O)cs1 +O=C(Cn1cnnn1)Nc1nnc(C2CCCCC2)s1 +Cc1ccc(CNC(=O)NCC2CCCO2)c(C)c1 +CC(CNc1ccc(C(N)=O)nn1)Cn1cccn1 +CCCNC(=O)c1c(C)c(C(=O)OCC)n(CC)c1C +O=C(OCCc1cccnc1)c1ccc2c(c1)OCCO2 +CCn1c(=O)c(C(=O)Nc2ccccc2C)nc2ccccc21 +Cc1csc(SCC(=O)Nc2ccc(F)cc2N)n1 +COc1ccc(CNC(=O)NC(C)c2c(C)noc2C)c(OC)c1 +Cc1nnsc1C(=O)NCC(=O)NC(C)(C)C +N#Cc1ccsc1NC(=O)c1cc(N2CCCC2=O)ccc1Cl +O=C(COc1ccc(Cl)cc1)N1CCN(c2ncccn2)CC1 +CC1CN(C(=O)c2ccc(SCc3cscn3)cc2)CC(C)O1 +CCOC(=O)C(N)Cc1cc(F)cc(C(C)=O)c1 +O=C(Cc1ccc(-n2cccn2)cc1)Oc1ccccc1 +CCn1c(-c2ccccc2)ccc1C(O)C(F)(F)F +CC(CC#N)N(C)Cc1ccc(C#CCCO)cc1 +NC(=O)c1c(NC(=O)c2cccnc2)sc2c1CCCCC2 +CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(F)cc2F)cc1 +Cc1cc(-c2nn3c(-c4ccccc4)nnc3s2)n[nH]1 +CCCCc1noc(CN2CCOC(c3ccc(F)cc3)C2)n1 +Cc1ncc(CNc2ccc3sccc3c2)s1 +O=C(Nc1ccc(OC(F)F)cc1)N1CCN(C(=O)C2CC2)CC1 +Cc1nn(C)cc1CC(C#N)C(=O)NCCc1ccccc1 +Cc1nc2ccc(NC(=O)C3CCCN(S(C)(=O)=O)C3)cc2o1 +COc1ccc2[nH]cc(CNc3cnns3)c2c1 +CN1C(=O)CCC2(CNC(=O)c3cnccn3)CCCC12 +COc1cc2c(c(CN3CCOC4(CCC4)C3)c1)OC(C)C2 +CC(c1cccs1)N(C)C(=O)c1cccc(F)c1 +CCOc1ccccc1C(=O)Nc1ccc(-n2ccnc2)nc1 +CCOC(=O)C1=C(N)OC(C)=C(C(N)=O)C1c1cccc(OC)c1 +Cc1ccc2cc(CN(C)C(=O)C3CCCCC3)c(=O)[nH]c2c1 +COc1cc(C#N)ccc1OC(=O)CCC1CCCO1 +CC(=O)N(C)CC(=O)Nc1ccc(OCC(F)(F)C(F)F)nc1 +CCCOc1ccc(CCC(=O)N2CCc3ccccc32)cc1N +N#Cc1ccc(NC(=O)CCSc2ccccc2F)cc1 +C=Cn1ncc(CN(Cc2ccccc2)CC2CCCO2)c1C +Cc1nc(C(=O)Nc2nc3ccccc3[nH]2)cs1 +CC(=O)N(c1cccc(N)c1)c1nn2c(nc3ccccc32)[nH]1 +Cc1nc(-c2noc3ccc(C(=O)NCCc4ccncc4)cc23)co1 +CCc1ccc(CCC(=O)N2CCN(CCO)CC2)cc1 +CC1CN(C(=O)c2scnc2C2CC2)C1c1ccccc1 +O=S(=O)(NCCCOC1CCCC1)c1cccc(Cl)c1 +CCn1c(SCC(=O)c2cc(C)n(CC)c2C)nnc1C1CC1 +CCOC(=O)C1CCCN(c2ccc3nnc(C(F)(F)F)n3n2)C1 +COC(=O)CCCS(=O)(=O)c1ccc(F)cc1 +CC(C)Cc1ncc(CN2CCCC(n3cccn3)C2)s1 +CCc1ccc(NC(=O)C(O)c2ccc(F)cc2)cc1 +CC(c1ccccc1F)N(C)C(=O)Nc1ccncc1 +COc1cc(C)ccc1NC(=O)c1cccc(N2CCCC2=O)c1 +O=C(CCc1ccncc1)Nc1cccc(Oc2ncccn2)c1 +Cc1ccc(Cn2nccc2NC(=O)c2ccoc2)o1 +CC(C)Cc1cc(C(=O)N2CCCC2C(N)=O)[nH]n1 +Cc1ccc(C(CNC(=O)c2cc(C)cs2)OCCO)cc1 +CSc1ncccc1C(=O)Nc1c(C)cccc1C(C)C +CCOc1cc(C)ccc1NCc1cnc(C)s1 +COC(CNC(=O)c1ccccc1SC)c1ccsc1 +Cc1cc(F)ccc1S(=O)(=O)NCCCOC1CCCC1 +COc1cccc(C(=O)OCCNc2ncccn2)c1 +C=C(C)Cn1nnc(CO)c1COc1ccc(C)cc1 +COCC(=O)c1cc(Br)ccc1OCC(C)C +CCOc1ccc(C(=O)NCC2CN3CCCC3CO2)cc1OC +O=C(C1CCN(S(=O)(=O)c2ccccc2)CC1)N1CCCC1 +C#CCOc1ccc(CCNC(=O)Cn2cccn2)cc1 +CCc1nc(CCNC(=O)c2nc3nc(C)cc(C)n3n2)sc1C +COc1cccc(C(=O)NC(C)C2CCOC2)c1F +CN(C)c1ccc(C(=O)N2CCc3cc(F)ccc3C2)cn1 +NC(=O)c1cc(NCC(=O)Nc2cc(F)ccc2F)ccc1Cl +Cc1ccccc1C(=O)NCCC(=O)NCC1CC1C +Cc1nc(-c2cccc(Cl)c2)sc1C(=O)NCCO +CN(C)C(=O)COc1cccc(CNC(=O)C2CC3CCC2O3)c1 +CNCC(=O)OCc1cc(Br)cs1 +CCOC(=O)c1nn(-c2nc3ccccc3[nH]2)c2ncccc12 +O=C(Nc1ccnn1C1CCCCC1)c1cnns1 +O=c1[nH]c(CSc2nnnn2C2CCCC2)nc2ccccc12 +Fc1ccc2c(c1)nc(-c1ccncc1)n2CC(F)(F)F +COc1ccc(OC)c(C(C#N)CC(=O)NCc2ccco2)c1 +Cc1csc(N(CC(F)(F)F)C(=O)CCOC(C)C)n1 +COc1ccc(NC(=O)CN(C)C(=O)c2c[nH]c3ccccc23)cc1 +COc1ccc2[nH]c(C(=O)NC3CCCC3)cc2n1 +CN(C)C(=O)CCNC(=O)Nc1ccc(Cl)c(S(N)(=O)=O)c1 +C=CCCC(=O)Nc1cc(OC)c(Cl)cc1OC +Cn1ncc2c(=O)n(Cc3ncc(-c4ccccc4)o3)cnc21 +CCCCn1nc2c(S(=O)(=O)N3CCOCC3)cccn2c1=O +COCCOC1CC2CN(C(=O)c3cscn3)CCN2C1 +CCOC(=O)c1csc(NC(=O)C2CC(=O)OC2(C)C)n1 +CCCC(NC(N)=O)C(=O)NCc1ccc(OC)cc1 +Cc1nc(C(C)(C)NC(=O)Nc2ccccc2F)sc1C +Cc1cccc(C)c1NC(=O)COc1ccc2c(C)cc(=O)oc2c1 +O=C(CNC(=O)c1ccccc1Cl)NC1CC1 +CCOCCNC(=O)NCCc1cc(Cl)cc(Cl)c1 +Cc1noc(C)c1C(C)NC(=O)NCc1cn(-c2ccccc2)nn1 +O=C(c1csc(-c2cnccn2)n1)N1CC=C(c2ccccc2)CC1 +CC(=O)NC1(C(=O)NCc2ccc3c(c2)OCO3)CCCCC1 +CCCn1c(=O)c2ccccc2n(CC(=O)Nc2nccs2)c1=O +CCCCN(C)S(=O)(=O)NC1(C(=O)NC)CCCCC1 +CCOc1ccc(CC(=O)Nc2ccc(C(=O)N(C)C)c(C)c2)cc1 +CC(C)(C)CCNS(=O)(=O)c1cccc(F)c1 +Cc1nnsc1CN(C)c1nnc(C2CC2)o1 +CC(C)n1cc(S(=O)(=O)N2CCN(Cc3ccccc3)CC2)cn1 +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)COc1cccc(F)c1 +COc1ccc(F)cc1COC(=O)c1ccc(-n2cnnn2)cc1 +CCc1noc(CN(C)C(=O)c2cc(OC)c(C)c(OC)c2)n1 +CCOC(=O)c1ccsc1NC(=O)COc1ccc(F)cc1 +CSc1ncc(C(=O)NC(C)C)n1-c1ccc(F)cc1 +COC(=O)c1ccsc1NC(=O)COc1ccccc1F +O=C(Cc1cccs1)NC1CC(=O)N(c2ccc(Cl)cc2)C1 +Cc1ccc(CN(C)C(=O)Cc2csc(-c3cccnc3)n2)o1 +COc1ccc(OCn2nc(N)cc2C)c(Cl)c1 +COc1ccc(-c2n[nH]cc2CNc2cnn(-c3ncccn3)c2)cc1 +COc1ccc(-n2ccc(=O)c(-c3nc(-c4ccccc4)no3)n2)cc1 +Cc1ncsc1C1NCCc2c(O)ccc(Cl)c21 +CCNc1ccc(C(=O)OCC)cc1NC(=O)C1CCC1 +CCCCNC(=O)C1CCCN(C(=O)Nc2c(C)cccc2C)C1 +CCOCCCCNC(=O)N1CCc2ccc(Cl)cc2C1 +COc1ccc(Nc2nc(C(=O)NCC(=O)NC3CC3)cs2)cc1 +CC(C)(C)OC(=O)NCCNC(=O)c1scnc1C1CC1 +CC1CCCC(NC(=O)CN2CCN(C3CC(C)OC3=O)CC2)C1 +O=c1nc2n(Cc3ccccc3)c3cc(Cl)ccc3cc-2c(=O)[nH]1 +COc1ccc(CNC(=O)Nc2ccccc2CC(N)=O)cc1 +O=C(Nc1cn[nH]c1)Nc1ncc(-c2ccccc2)s1 +CCS(=O)(=O)N1CCN(CCc2ccccc2)CC1 +c1ccc(-c2cnnc(NCC3COc4ccccc4O3)n2)cc1 +NC(=O)c1cc(N)n(-c2ccc(C(F)(F)F)cc2)n1 +CC1COCCN1C(=O)c1ccc(CNC(N)=O)cc1 +CCC(CC)CN(CC)C(=O)c1cnc2c(c1)c(C)nn2C +COc1ccc(-c2nc(COn3nnc4ccccc43)no2)cc1 +O=C(NCc1cccnc1)Nc1ccc2c3c(cccc13)CC2 +COCCOC1CCN(C(=O)c2ccnnc2)C1Cc1ccncc1 +Cc1[nH]c(SCC(=O)N(C)C(C)C)nc1Cc1ccccc1 +Cc1ccc(NC(C)c2cccc(-n3cnnn3)c2)cc1C +CCN(C)C(=O)CCNS(=O)(=O)c1ccc(C(C)(C)C)cc1 +Cc1ccc(NC(=O)C2CCCCC2)c2[nH]ncc12 +CCC(NC(=O)c1cn(Cc2ccccc2C)nn1)c1ccc(C)cc1 +CC1CC1C(=O)NCCNS(=O)(=O)c1ccccc1 +CCCN(CCC)C(=O)CN1CC(C)Oc2cccc(N)c21 +CC(C)CN(CCC#N)Cc1c(F)cccc1Cl +CC(Cn1ccnc1)NC(=O)c1occc1COc1ccccc1 +CN(C)C(=O)Cn1nc(-c2cccs2)oc1=O +COC(=O)c1cccn(CC(=O)c2ccc(Cl)cc2Cl)c1=O +CCn1nc(C)c(CCN(C)C(=O)Nc2cccc(C)c2)c1C +CCOc1ccc(C2=CCN(S(=O)(=O)Cc3ccon3)CC2)cc1 +CCS(=O)(=O)Nc1cc2c(C(=O)OC(C)C)c(C)oc2cc1C +CCC(=O)Nc1sc2c(c1C(=O)OC)CCC(C)C2 +O=C(Cn1nnc(-c2ccsc2)n1)NCC1CCCO1 +C#Cc1cccc(NC(=O)Cc2ccc(O)cc2)c1 +CC(C)N(C)S(=O)(=O)NC1CCc2c(Cl)cccc21 +COC(=O)C(Sc1ncn[nH]1)c1c(F)cccc1Cl +Cc1cc(C(F)(F)F)nn1CCCNC(=O)Cc1ccc(F)cc1 +Cc1noc(-c2ccccc2)c1C(=O)Nc1ccc(-n2ccnn2)cc1 +COCC(NC(=O)C1COc2ccc(F)cc2C1)c1ccco1 +CC1CCCCC1NC(=O)c1cc2c([nH]c1=O)CCC2 +CN1CCN(C(=O)C2CC(NC(=O)N(C)C)CN2C)CC1 +O=C(CSc1nc(CC2CCCC2)n[nH]1)N1CCOCC1 +Cc1ccc(N2CCN(C(=O)c3cc(C4CC4)n[nH]3)CC2)c(C)c1 +Cc1ccc(N2CC(C(=O)NCc3cnn4ccccc34)CC2=O)cc1 +Cc1ccc(C)c(CC(=O)N2CCC(C(N)=O)CC2)c1 +CCN(C)C(=O)c1nn(-c2ccccc2F)c2c1CCC2 +CCN(CCO)C(=O)c1ccc(COc2ccccc2C#N)o1 +CCn1cnnc1CNC(=O)Cn1ccc2ccc(Cl)cc21 +COc1cc(O)ccc1CNc1cc(Cl)ccn1 +Cc1ccc2oc(=O)c3cc(C(=O)Nc4nccs4)sc3c2c1 +O=S(CCN1CCOCC1C1CC1)c1cc(Cl)ccc1Cl +COc1ccccc1NCC(O)c1ccccc1F +CCOc1ccc(-c2c(C3CC3)n[nH]c2N)cc1OCC +Cc1cc(OCC(=O)NC(C)c2ccc(-n3ccnc3)cc2)no1 +CS(=O)(=O)N1CCN(c2cc(=O)n3ccccc3n2)CC1 +CCC(C)C(=O)NC(C)c1ccc(S(C)(=O)=O)cc1 +COc1ccc(NC(=O)CCc2ccsc2)cc1S(N)(=O)=O +CC1CCCCC1Nc1ccc(S(C)(=O)=O)cc1 +O=C(NCCc1ccc(F)cc1)c1ncccc1O +COc1ccc(C2CC(=O)NC3=NC(c4ccccc4)=NC(=O)C32)cc1 +Cc1sc2ncnc(SCCC(=O)Nc3ccccn3)c2c1C +N#Cc1cccc(C2NCCc3cc(F)cc(F)c32)c1 +CC(=O)Nc1cc(NC(=O)N(C)C(C)c2cccc(O)c2)ccc1C +Cc1cccc(NC(=O)Cc2c(C)nn(C)c2C)c1 +O=S(=O)(NC1CCC(C(F)(F)F)CC1)c1ccc(F)cc1F +Cc1cccc(-c2cccc(CNC(=O)c3cc[nH]n3)c2)c1 +CC(=O)N1CCC(c2nnc(-c3cncn3C)o2)C1 +CC(NC(=O)N(CCCO)C1CCc2ccccc21)c1cnn(C)c1 +Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CCC3)CC2)cc1 +Cc1onc(-c2ccccc2)c1C(=O)N1CC(C)CC(C)C1 +CNC(=O)CCc1cc(C)nc(C2CCN(c3ccccc3)CC2)c1 +Cc1nn(-c2ccc(F)cc2)c(C)c1CN1CCOC(C#N)C1 +CCOc1ccc(NC(=O)CNc2ccc(NC(C)=O)cc2)cc1 +Nc1nc2nc(C(F)(F)F)cc(C(F)(F)F)n2n1 +O=C(c1cc(F)ccc1F)N1CCN(c2ncccn2)CC1 +CC(=O)c1ccc(OCC(=O)Nc2nc3ccccc3s2)cc1 +O=C(NCCCNc1ncccn1)c1scnc1C1CC1 +Cc1ccc(CCCC(=O)N2CCC(C(N)=O)c3ccccc32)s1 +Cc1csc(CNC(=O)C2COc3ccccc3C2)n1 +COc1cc(NC(=O)n2ncc3ccccc32)cc(OC)c1 +CCC(OC)C(=O)Oc1cccc(C(=O)NC)c1 +CN(C)S(=O)(=O)N1CCCC1c1ccsc1 +CC(=O)NC(CC(=O)Nc1ccc(C)c(Cl)c1)c1ccccc1 +COCc1cccc(NS(=O)(=O)c2ccc(F)cc2C)c1 +CC1CC(c2ccccc2F)N(C(=O)CNC(=O)c2cccs2)C1 +Cn1c(SCc2ccon2)nc2ccccc2c1=O +O=C(Nc1nc(C(=O)NCc2cccs2)cs1)c1ccccc1 +COc1cc(CO)ccc1OCC(=O)NC(C)c1ccccc1 +Cc1cc(C)nc(C(C#N)C(=O)CCSc2ccccc2)n1 +CC(=O)Nc1nc(C(=O)NCC(O)c2ccco2)cs1 +CC(=O)c1ccc(Oc2cc(-n3nc(C)cc3C)ncn2)cc1 +N#CCCN(CCC(F)(F)F)CC(=O)N1CCc2ccccc2C1 +COC(=O)CCCNC(=O)Cn1ccc2ccc(F)cc21 +Cc1ccc(Oc2ncnc(NC3CCCC3)c2N)cc1 +O=C(CN1CCOCC1)Nc1nnc(-c2cccs2)s1 +CCc1nc(CS(=O)(=O)c2ccc(NC(C)=O)cc2)no1 +O=C(CCNC(=O)c1cc2ccoc2cn1)Nc1cccc(Cl)c1 +Cc1ccn2c(=NC(=O)CCCc3nc(C(C)(C)C)no3)[nH]nc2c1 +Cc1nc2n(n1)C(c1cc(F)cc(F)c1)C1C(=O)CCCC1=N2 +N#CC1C=Cc2c(ccc3cccnc23)N1C(=O)c1ccccc1 +Cc1ccc(CN2CCc3ncnc(C4CCOC4)c3CC2)s1 +COc1cc(C)c(C)cc1-c1cc(N)c(=O)n(C)n1 +COc1cc(-c2c(C)cn(C)c(=O)c2C#N)cc(OC)c1OC +Cc1ccccc1NC(=O)CSc1nnc(-c2ccccn2)n1N +CC(CNc1ncnc2cccc(F)c12)CN1CCCC1=O +CNC(=O)c1cc(NC(=O)c2cc(OC)c(OC)cc2C)ccc1F +Cc1c(C(F)(F)F)n[nH]c1NC(=O)C1CCCC1 +CC(C)(NC(=O)c1nn(-c2ccccc2F)c2c1CCC2)C(N)=O +CC1CCC(NC(=O)c2ccc(N(C)C)nc2)CC1 +O=C(Nc1cccc(C(=O)NC2CC2)c1)c1ccc(Cl)cc1 +Cc1ccc(CC(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)cc1 +N#CCSc1cccc(C(=O)N(C2CC2)C2Cc3ccccc3C2)c1 +NC(=O)C(c1ccc(F)cc1)n1nnc(-c2cccc(F)c2)n1 +CCc1ccc(OCC(=O)Nc2ccc(-c3nncn3C)cc2)cc1 +O=C(NCC1(O)CCc2ccccc2C1)c1ccccc1 +O=C1COc2cc(NC(=O)c3ccc4nccnc4c3)ccc2N1 +COc1ccccc1NC(=O)Nc1ccc(C)cn1 +CC(CC#N)N1CCN(C(=O)c2ccc(Cl)cc2F)CC1 +COc1ccc(C(=O)Nc2cccc(C3OCCCO3)c2)cc1OC +CC(C)OCCS(=O)(=O)N1CCc2cc(F)ccc2C1 +CCn1cnc(NC(=O)NCCC2=CCC3CC2C3(C)C)n1 +Cc1ccnc(NC(=O)NCc2ccccc2-n2ccnc2)c1 +CCn1ccc(Cn2c(C)cc(=O)c3ccccc32)n1 +Cc1ccccc1COc1cccc(NC(=O)CNS(C)(=O)=O)c1 +CCOc1ccccc1NC(=O)c1cccc(NS(C)(=O)=O)c1C +O=C(CCOc1ccccc1F)NCc1ncc(-c2ccccc2)o1 +COCCn1cnnc1SCC(=O)Nc1ccc(Cl)cc1C +c1csc(C(N2CCOCC2)N2CCOCC2)c1 +CC(C)CCn1c(=O)oc(=O)c2cccc(Cl)c21 +Cn1cc(CCNS(=O)(=O)c2cc(Cl)cc(Cl)c2)cn1 +Cc1cc(C)cc(NC(=O)C(C)N2CCN(c3ncccn3)CC2)c1 +O=C(CN1CCN(C(=O)C2CC2)CC1)NCC1(c2ccccc2)CC1 +Cc1ncc(CSc2nc(C(C)(C)C)cs2)c(CO)c1O +CCc1nnc(COc2ccc(Cl)cc2C(C)=O)o1 +O=C(NC1(CCO)CCC1)c1cn(Cc2cccc(F)c2)nn1 +CC1CCCN(C(=O)NCCOc2ccc3c(c2)OCO3)C1 +C=CCN(Cc1cccc(C#N)c1)C(=O)c1ccccc1-n1cnnn1 +CC(=O)c1ccc(C(=O)N2CCOCC2CC(C)C)cc1 +CC(O)CCN(C)C(=O)Nc1cc(N2CCCC2=O)ccc1Cl +CC(C)(C)NS(=O)(=O)c1cc(NC(=O)N2CCCC2)ccc1F +Nc1ccc2c(c1)nc(CCO)n2Cc1cccnc1N +CN(Cc1cccs1)C(=O)c1ccc2c(c1)OCO2 +Cc1cccc(CC(=O)Nc2ccc(CC(=O)N(C)C)cc2)c1 +CC(C)(C)n1nc(C2CC2)cc1C(=O)NC1CCCNC1=O +Cc1cc(NC(=O)Cc2csc(-c3cccnc3)n2)[nH]n1 +CCCNC(=O)CNc1cc(C#N)ccc1OCC +Cc1nc2ccc(NC(=O)c3n[nH]c4ccccc34)cc2s1 +CCOCC(=O)NC(C)c1cnc(-c2ccncc2)nc1C +Cc1csc(NC(=O)C(C)Sc2ncnc(N)n2)n1 +COCCCNC(=O)c1cnc(C2CCCO2)nc1N +COCCNc1nc(-c2c(C)oc3c2CCC3)cs1 +Cc1ccc2nc(CNC(=O)CC3NC(=O)c4ccccc43)[nH]c2c1 +O=c1[nH]c2cc(NS(=O)(=O)Cc3ccc(F)cc3)ccc2o1 +Cc1ccc(C2(O)CCN(c3cc(C(N)=O)ccn3)CC2)nc1 +COc1ccc(-c2cc(C(=O)N3CCN(CCO)CC3)no2)c(F)c1 +COc1cccc(Cn2nc(-c3cccnc3)oc2=O)c1 +CC(C)C(=O)NCCNC(=O)C(C)(C)c1ccccc1F +Cc1nnc(C2Cc3ccccc3CN2Cc2ccc(C#N)cc2F)o1 +Cc1ccc(Cl)cc1NC(=O)C1CCCN1C(N)=O +O=C(NC12CC3CC(CC(C3)C1)C2)N1CCOCC1 +Cc1cc(C(=O)CSc2ncc(C#N)c(N)n2)c(C)s1 +Cc1cc(NC(=O)Cn2cnc3c(oc4ccccc43)c2=O)no1 +COc1ccccc1CCNC(=O)c1ccc(-n2nc(C)cc2C)cc1 +Cc1cccnc1NC(=O)NCc1sccc1C +O=C(Nc1ccc(SCc2ccccc2F)nn1)c1ccco1 +Cc1cc(C)n(Cc2cccc(NC(=O)c3ccc[nH]3)c2)n1 +CC(=O)NCCNS(=O)(=O)c1ccc(C(=O)C(C)C)cc1 +CCOc1cccc(CCn2nc(C)c(N)c2C)c1 +CCN(c1ccccc1)S(=O)(=O)c1ccc2nnc(C)n2c1 +COc1ccnc(N2CC3OCC(=O)N(c4ccccc4)C3C2)n1 +Cn1cc(C(=O)N2CCCC(c3ccn[nH]3)C2)ccc1=O +Cc1c(NC(=O)Nc2ccccc2)cccc1C(=O)N1CCOCC1 +COc1cc(OC)cc(OCCC2OCCO2)c1 +CCCOc1cccc(-c2nc(N)nc(C)c2C(=O)OCC)c1 +CC(=O)NCCCC(=O)N1CCc2cc(Br)ccc21 +CC(C)(C)Oc1cncc(OC2CC2)c1Br +Cc1ccc(OCCN(C)C(=O)C(C)NC(=O)c2ccccc2)cc1 +CCOC(=O)c1nnn(-c2ccc(CC)cc2)c1C +CCc1nc(NCc2ccncc2)cc(OCC(C)C)n1 +Cn1cc(-c2csc(-c3ccccc3O)n2)cn1 +CC(C)=CC1C(C(=O)OCC(=O)NC(C)C)C1(C)C +Cc1nn(C)cc1C(=O)NCCN1CCOCC1 +O=C(CN1CCCCCC1=O)Nc1ccc2c(c1)OCO2 +COC(=O)C1CC(NC(=O)c2ccco2)CN1C(C)C +COc1cc(F)ccc1NC(C)c1scnc1C +Cc1ccc2c(CC(=O)Nc3ccc4c(c3)COC4)coc2c1 +O=C(NCc1ccccn1)c1ccc2nc(-n3cccc3)sc2c1 +Cc1ccc(NC(=O)c2scnc2C2CC2)cn1 +COc1ccc(C(C)C)cc1C(O)CN1CC(C)OC(C)C1 +Cc1ccc(CNC(=O)CCC(=O)c2ccc(C)cc2)cc1 +CC(C)n1nccc1NC(=O)NC1CCN(c2c(F)cccc2F)C1 +CNS(=O)(=O)c1cccc(C(C)NCc2ccc(C)s2)c1 +CCC(OC(=O)c1ccc(N)cc1)C(=O)Nc1ccncc1 +Cc1ccccc1NC(=O)CC(C#N)c1ccccn1 +COCCN(Cc1nc2c(cnn2C)c(=O)[nH]1)CC(C)C +O=C(CCn1ncc(N2CCOCC2)cc1=O)N1CCCC1 +CC(=O)c1c(C)nc(C)nc1SCC(=O)NC1CCCCC1 +COc1cccn(CC(=O)N2CCCC2c2cc(C)no2)c1=O +COC(=O)C(C)(C)NC(=O)c1nn(-c2ccccc2C)c2c1CCC2 +CC1CCC(NC(=O)N2CCC(OCC3CCCO3)CC2)CC1 +CC(C)(C)OC(=O)NCCc1cccc2c1NCCC2 +CCCNC(=O)c1cccc(NC(=O)NC(C)C(C)CC)c1 +COc1ccc(-c2noc(SCC(=O)Nc3ccccc3)n2)cc1 +Cn1c(CNCCc2c(F)cccc2F)cc(=O)n(C)c1=O +O=C(Nc1ccccc1)c1cccc(N2CCCC2=O)c1 +CC(Cc1noc(-c2ccnnc2)n1)N(C)C(=O)OC(C)(C)C +Cc1cc(C)c2sc(N3CCN(C(=O)C4CC4)CC3)nc2c1 +CSc1ccccc1NC(=O)CN(C)C(=O)c1cc(C)oc1C +CC(C)(NC(=O)c1ccc(CNC(N)=O)cc1)c1cccc(F)c1 +NC(=O)c1cccc(NC(=O)c2ccccc2Cl)c1 +O=C(Nc1ccc(Cl)cc1NC(=O)c1ccco1)c1cc[nH]n1 +Cc1noc(C)c1NC(=O)CCn1ncc2cccc(C)c21 +Cn1c(=O)oc2cc(Nc3nccc(C(F)(F)F)n3)ccc21 +CCOc1ccc(F)c(C(=O)NC(C)(C(=O)OC)C2CC2)c1F +O=C(c1cscn1)N1CCc2onc(-c3ccccc3)c2C1 +c1ccc(CN2CCCC(c3cc4cccnc4[nH]3)C2)cc1 +O=C(Cc1cn2ccccc2n1)NCCOc1ccc(Cl)cn1 +CCN(CCO)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +Cc1ccccc1CC(=O)N(Cc1ccco1)CC1CCCO1 +Cc1nc(C)c(CC(=O)N2CCN(C(=O)c3ccco3)CC2)c(=O)[nH]1 +COCCCNC(=O)C1CCN(C(=O)Nc2cc(C)ccc2C)CC1 +COc1ccccc1C1CC(=O)Nc2nc(-c3ccccc3)[nH]c(=O)c21 +CC1NCCN(c2ccc(C(F)(F)F)cc2)C1=O +CCCCC(=O)N(Cc1ccoc1)Cc1cccs1 +Oc1ccc(F)c2c1CCNC2CCCc1ccccc1 +COC(=O)NCCCC(=O)NC1(c2ccccc2)CCCCC1 +O=C(Cc1ccc(Cl)cc1)NCC1CC(=O)N(c2ccccc2)C1 +CC(C)N(Cc1cccc(Cl)c1)C(=O)NCc1ncn(C)n1 +COc1ccc(OCCn2nnc(CO)c2C(F)(F)F)cc1 +CCOc1ccc(NC(=O)Cn2[nH]c(=O)c3ccccc3c2=O)cc1 +COCC(=O)N1CCCC(c2cccc(Cc3ccc(F)cc3)n2)C1 +CC1=C(C(=O)N2CCC3(CC2)CNC(=O)O3)C(C)NC(=O)N1 +CCCCN(CCO)C(=O)Nc1c(C)noc1CC +NS(=O)(=O)c1ccc(CNC(=O)CSc2ncccn2)cc1 +O=C(NCC(O)c1ccc(F)cc1)c1nc2ccccc2c(=O)[nH]1 +COc1ccc(CNC(=O)Nc2ccc(C(C)=O)c(C)c2)cc1 +NC(=O)C1(CNC(=O)C2CC3CCC2O3)CCOCC1 +CC(C)NS(=O)(=O)c1ccc(NC(=O)c2cnn(C)c2)cc1 +NC(=O)c1ccc(-c2nnn(CC(=O)NCC(F)(F)F)n2)cc1 +COc1c(F)cccc1CNc1ccccc1C#N +NC(=O)C1CCN(C(=O)CCc2ccccc2OC(F)(F)F)CC1 +Cc1ccc(-c2nc(CNC(=O)N3CC(C)OC(C)C3)co2)cc1 +COC(=O)c1ccc(OCC(=O)Nc2ccc(F)cc2)cc1 +CC1CC(c2cccc(Cl)c2)Cn2nc(N)nc21 +CC(=O)Nc1cccc(NC(=O)C(C)Sc2ccc(O)cc2)c1 +N#Cc1ccc(-c2noc(-c3cccc(OCC(F)F)n3)n2)nc1 +COc1ccccc1-c1nnc(NC(=O)c2nn(C)cc2C)o1 +CN(CC(N)=O)C(=O)CCNC(=O)c1ccncc1 +CC(O)C(=O)N1CCN(Cc2cc(C(N)=O)cs2)CC1 +CCc1cccc(OCCSc2nnc(C(F)(F)F)n2N)c1 +Cc1ccccc1CC(C)NC(=O)Nc1ccncc1 +Cc1ccc(N2CCOC2=O)cc1NC(=O)Cc1ccc(F)c(F)c1 +CS(=O)(=O)NCCNC(=O)Nc1cccc(F)c1 +CC(=O)N1Cc2ccccc2OC2(CCCN(C(=O)C3CC3)C2)C1 +Cc1cc(=O)c(CC#N)nn1-c1c(F)cccc1F +O=C(CCc1nncn1-c1ccccc1)Oc1ccc2cn[nH]c2c1 +CNC(=O)c1ccc(OC)c(NC(=O)NCc2cnc(C)s2)c1 +CCC1COC2(CCCN(C(=O)c3ccc4[nH]cnc4c3)C2)C1 +C#CCn1c(C2CC(=O)N(CCOC)C2)nc2ccccc21 +O=C(c1c[nH]cn1)N1CCCC2(COCCN(c3nccs3)C2)C1 +CCc1ccccc1NC(=O)CN(C)C(=O)C1CCCC1 +CCN1CC(C(=O)NCCc2csc(-c3ccncc3)n2)CC1=O +O=C(COC(=O)Cc1cccs1)Nc1ccc(Cl)cc1F +Cc1ccc(F)cc1NC(=O)c1cccc(N2CCCC2=O)c1 +CC1CN(c2ccc(C(=O)N3CCc4ccccc43)cn2)CC(C)O1 +CC(=O)c1cccc(NC(=O)N2CC(O)CC2CO)c1 +CCCc1ncncc1C(=O)N1CCC2(CCCNC2=O)C1 +CS(=O)(=O)c1ccc(C(=O)N2CCCC3(CCCCCC3)C2)o1 +CC(C)n1ccnc1C(=O)Nc1cccc(C#N)c1 +NC(=O)C1(NC(=O)c2ncn(-c3ccccc3)n2)CCCCC1 +C#CCN1CCN(CC(=O)N(CC(C)C)C2CC2)CC1 +c1ccc(-n2ncc(CNc3cccnc3)n2)cc1 +Cc1sc(=O)n(CC(=O)NCCCN2CCCC2=O)c1C +Cc1cn(-c2ccccc2Cl)nc1NC(=O)C1CC(=O)C1 +CCc1onc(C)c1NC(=O)CCc1nc2ccccc2s1 +CNC(=O)NCC(=O)NC1CCCCC1Cc1ccccc1 +O=C1COc2nc3ccccc3cc2CN1Cc1ccc2c(c1)OCO2 +Cc1ccc(NS(=O)(=O)c2ccc(F)c(F)c2)c(F)c1 +Cn1cc(CNc2cc(Cl)cc3cccnc23)cn1 +Cc1nc2c(C#N)cnn2c(C)c1CCC(=O)N1CCNC(=O)C1 +COC(=O)COc1ccc(S(=O)(=O)N2CCCCC2)cc1C +O=C(Nc1ccc(Cl)c(Cl)c1)c1cccnn1 +CCOC(CC)C(=O)Nc1cccc(NC(N)=O)c1 +Cc1cnc(C)c(SCC(=O)c2ccc(Br)cc2)n1 +CC(C)c1ccccc1NC(=O)NCc1ccoc1 +CC(C)(C)c1cc(NC(=O)c2cccnc2N2CCOCC2)[nH]n1 +O=C(CSc1cc(Cl)ccc1Cl)N(CCO)C1CC1 +Cc1cc(C)n2ncc(-c3noc(C4CC(=O)N(C(C)C)C4)n3)c2n1 +c1ccc(-c2noc(CNc3ccccc3-n3cccn3)n2)cc1 +COC(=O)CCCCNC(=O)N1CCN(c2ccccc2)CC1 +Cc1ccccc1-n1ncc(C(=O)NCC(N)=O)c1C +CC1CC1C(=O)N1CCc2ccc(S(=O)(=O)N3CCCC3)cc21 +C=CCN(Cc1cccs1)C(=O)c1ccccc1 +CC(C)(C)c1noc(Cn2c(=O)cnc3ccccc32)n1 +CC1c2cccn2CCN1C(=O)CCc1nc(C2CC2)no1 +CCc1onc(C)c1NC(=O)NCCc1cc(F)ccc1F +CCC(=O)NCC(O)c1cc(C(C)C)ccc1OC +COCCCCNc1ccc(-c2nc(C)cc(=O)[nH]2)cn1 +Cn1nc(C(=O)Nc2ccc(Cl)cn2)c(=O)c2ccccc21 +COc1cccc(CNC(=O)N2CCCC2c2cc(C)on2)c1 +CC(Sc1ccccc1)C(=O)NCCCC(N)=O +COc1ccc(N2C(=O)c3ccccc3NC2(C)C)cc1 +C=CCNC(=O)c1cccc(S(=O)(=O)N(C)C2CCCCC2)c1 +CCc1cnc(C(C)NC(=O)c2c[nH]nc2-c2ccccc2F)s1 +CNC(=O)c1ccc(CSc2nnnn2C2CCCCC2)cc1 +COC(=O)Cc1cccc(OCC(=O)Nc2ccc(C)cc2)c1 +CCCCCNC(=O)N1CCCN(C(=O)c2ccc[nH]c2=O)CC1 +CC(C)OCc1ccc(C(=O)N(C)Cc2cccc(C#N)c2)cc1 +CC(O)c1nc2ccccc2n1Cc1cccc(Cl)c1 +CCC(C(=O)OCCN1CCCC1=O)c1ccccc1 +COc1cccc(C(=O)NCc2cccc(-c3ccccn3)c2)c1F +O=C(Cn1c(=O)cnc2ccccc21)OCC1CC1(Cl)Cl +COc1ccccc1N1C(N)=NC(N)=NC12CCCC2 +O=C(CCn1cnc2sccc2c1=O)N1CCOCC1C1CC1 +CCNC(=O)c1ccc(NC(=O)COc2ccc(Cl)c(C)c2)cc1 +Cc1cccc(C2CC(c3ccccc3)Nc3ncnn32)c1 +O=C(NCc1nc[nH]n1)c1ccc(-c2ccco2)[nH]c1=O +O=C(CCCN1CCOC1=O)Nc1nncs1 +CC(C)(C)c1ccc(O)c(NC(=O)c2nccnc2N)c1 +Cc1ccccc1NC(=O)C1(C)Cc2ccccc2C(=O)O1 +CC(c1ccncc1)N(C)C(=O)Nc1cccnc1 +O=C(Nc1cc(F)cc(Cl)c1)c1cnc(C2CCCO2)s1 +COC(=O)CNC(=O)c1ccc(-c2ccc(Cl)cc2C)o1 +Cc1ccc(C)c(S(=O)(=O)NCC2(O)CCCC2)c1 +COc1cccc(S(=O)(=O)C(C)C(=O)N(C)Cc2ccccc2)c1 +COC(=O)c1c(NC(=O)C(C)C)sc(C(=O)N(C)C)c1C +CC1CCCCN1c1ncnc(Oc2cccc3cccnc23)c1N +COc1ccc(-n2cc(CNC(=O)c3cc(C)cc(C)c3)nn2)cc1 +O=C(Nc1ccccc1OCc1cccc(Cl)c1)c1ccnnc1 +CCC(=O)N1CCN(c2ccc(C)c(F)c2)C(=O)C1C +CC(NC(=O)N1Cc2ccccc2C1)c1cccc(N2CCCC2=O)c1 +NC(=O)Cn1c(=O)n(Cc2ccccc2Cl)c(=O)c2sccc21 +CCCOc1cccc2c1C(c1cc[nH]c1)NCC2 +COc1ccc(NC(=O)c2n[nH]cc2N)cc1Cl +CCN(CC)C(=O)CSc1nnc(C2CCCCC2)n1CC +CCc1ncc2c(n1)CN(C(=O)C(C)n1c(=O)oc3ccccc31)C2 +Cn1nnnc1SCC(=O)c1ccc2c(c1)CCC2 +CCOC(C)c1nccn1CC(=O)NC(C)(C)CC +CC1CCN(C(=O)c2cc(-c3ccccc3)on2)CC1 +CC(=O)c1ccc(NC(=O)C(C)NC(=O)c2ccco2)cc1C +CCC1CCCCN1C(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +O=C(CCc1ccco1)N1CCN(Cc2cccc3ccccc23)CC1 +CCn1c(=O)ccn(Cc2cccc(Br)c2)c1=O +CC(C)C(NC(=O)c1cccs1)C(=O)Nc1ccc2[nH]ncc2c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)NCC(C)(C)c1ccncc1 +Cc1nc(C)c(CCC(=O)Nc2nc(-c3ccco3)cs2)c(=O)[nH]1 +CCNc1nc2cc3c(cc2s1)CCCN3S(C)(=O)=O +CC1COCCN1c1ccc(S(C)(=O)=O)cc1N +CC(NC(=O)NC(C)c1ccccn1)c1ccc(F)cc1 +Cc1nc2ccc(NC(=O)C3CCCN(C(=O)C4CC4)C3)cc2s1 +CCOCCCNC(=O)Cn1cnc2c(cnn2C)c1=O +CC(=O)N1CCN(C(=O)Cn2ncccc2=O)CC1 +Cc1nnc(CNC(=O)CN(C)c2nc3ccccc3s2)o1 +COC(=O)c1ccc(CNCc2nc(C)sc2C)cc1 +O=C(C1CCCCC1)N1CCNC(c2ccccc2)C1 +CCCCCc1nnc(NC(=O)N(C)Cc2ccoc2C)s1 +COc1ccc(NC(=O)COc2cccc(C)c2)c2cccnc12 +O=C(CCc1cc2ccccc2[nH]c1=O)NC1CC1 +CCn1cnnc1CNC(=O)NC(C)C12CC3CC(CC(C3)C1)C2 +Cc1ccc(S(=O)(=O)NC2C3CCC(C3)C2CO)s1 +O=C(Nc1nnc(-c2ccno2)o1)c1cccc(Cl)c1 +O=C(CCSc1ccccc1Br)NCC1CCOC1 +COc1ccccc1CN(C)C(=O)c1cc(C)nc2onc(C)c12 +Cc1c(Cl)cccc1NC(=O)CNC(=O)Cn1cnc(C#N)n1 +Cc1cc(Cl)c(Cl)cc1S(=O)(=O)n1ccnc1C +COCC1CCCN1C(=O)c1ccc(N2CCCC2=O)cc1 +Cc1ccc(NC(=O)Nc2ccccn2)cc1N1CCCS1(=O)=O +COCCCNC(=O)c1cnn(-c2nccc(-c3ccco3)n2)c1C +Nc1cc(Br)ccc1Sc1nnnn1-c1ccccc1 +CC(C)C(=O)Nc1cnn(-c2ccccc2S(C)(=O)=O)c1 +COc1cccc(-c2nc(CC(=O)Nc3ccccc3)no2)c1 +CCOC(=O)CN(C(=O)c1cc(Cl)ccc1Cl)C1CC1 +CN(CCCNC(=O)N1CCC(O)(C(F)(F)F)C1)c1ccccc1 +Cc1cccc(C(=O)N2CCCc3c(C(N)=O)cccc32)n1 +Cc1nc(N(C)C)sc1CN(C)C(C)CC#N +O=C(OC1CCOC1=O)c1ccc(N2CCCC2=O)cc1 +COCCN(C)C(=O)c1ccc(=O)n(-c2ccc(F)cc2)n1 +Cc1nn(C)c(C)c1NC(=O)CSc1nc2ccccc2o1 +CC1(C)CCCN1C(=O)Cc1c(F)cccc1Cl +CN(C)C(=O)COc1cccc(NC(=O)CC2CC3CCC2C3)c1 +Nc1cccc(C(=O)OCC(=O)N2CCCCCC2)c1 +CC(C)C(=O)NCCNC(=O)c1cc2c(s1)-c1ccccc1CC2 +CC(C(=O)Nc1cc(-n2cnnn2)ccc1F)n1cccc1 +CC1Oc2ccc(-c3csc(NC(=O)C4CC4)n3)cc2NC1=O +CCCOc1cc(OC)cc2c1CCNC2c1ccc[nH]1 +CCN(C(=O)c1cccc(F)c1)c1ccccc1S(=O)(=O)CC +CC(CC(=O)NCC1(c2cccc(F)c2)CCOCC1)C1CC1 +Cc1cc(C)n(-c2ccnc(N3CCC(C(=O)NC4CC4)CC3)n2)n1 +COc1ccccc1CCC(=O)NCc1c(C)cc(C)[nH]c1=O +Cc1ccc(C)c(S(=O)(=O)NCCC(=O)N2CCOCC2)c1 +COc1cc(CC(C)(C)Cl)cc(OC)c1OC +O=C(Nc1ccccn1)c1cnc(-c2ccccc2)s1 +CCOC(=O)Cc1cc2c(cc1Cl)OCCO2 +Cc1cccc(N)c1S(=O)(=O)NCCS(N)(=O)=O +CC(C#N)CNC(=O)C1(Sc2ccccc2)CCCC1 +Cc1cc2oc(NCc3ccccc3)c(-c3cccnc3)c2c(=O)o1 +CCCOC(=O)N1CCC(c2nnc(Cn3cccn3)n2CC)CC1 +CC(=O)c1cnc(-c2cc[nH]c2)n1Cc1ccccc1 +CCOc1ccc(CN2CCn3c(nn(C)c3=O)C2)cc1 +COc1ccc(CNC(=O)c2cc3sccc3n2C)cc1OC +CC(C)C(=O)NC1CCOc2ccc(C(O)C(C)C)cc21 +Cc1nn(C)c(C)c1CC(C)C(=O)N1CCCCC1c1nccs1 +O=C(NCc1ccn(C2CCCC2)n1)NC(CO)c1ccccc1 +CN(CCN1CCCC1=O)Cc1cnc(C2CC2)s1 +CC(C)c1ccc(C(C#N)CC(=O)N2CCOCC2)cc1 +CCCCCCNC(=O)c1cnn2c(C)cc(C)nc12 +CC1CN(CCCNC(=O)COc2ccc(Cl)cc2)CC(C)O1 +COC1CCN(C(=O)c2ccnnc2)CC1Cc1cccc(C)c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1nccs1 +CCOCC1CCCC12CN(Cc1cccs1)CCO2 +Cn1nnnc1-c1cccc(NC(=O)c2ccccc2)c1 +Cc1nn2cccnc2c1C(=O)NC1C2CCOC2C1(C)C +CSc1nsc(NCC(=O)c2ccccc2)n1 +CC(=O)Nc1cccc(NC(=O)c2cc(N)ccc2Cl)c1 +CC(=O)Nc1ccc(NC(=O)CC(C)C)cc1Cl +NC(=O)c1ccc(NC(=O)c2cc(-c3cccc(Cl)c3)[nH]n2)cc1 +C=CCn1c(=O)sc2cc(NC(=O)CC(C)C)ccc21 +Cc1ccc(C(N)=O)cc1NC(=O)c1occc1C +O=C(CSc1ccncc1)N1CCOC(Cc2ccccc2)C1 +CNC(=O)COc1ccccc1CNc1cccc2c1CCCC2 +N#Cc1ccn2nc(-c3ccc(F)c(F)c3)nc2c1 +Cc1ccsc1CNC(=O)NCC1CCCOC1 +O=C(OCC1CCCCO1)C1COc2ccccc21 +CCCOC(=O)c1ccc(CNc2cn[nH]c(=O)n2)cc1 +CCc1cnc(CN(C)C(=O)c2cnc3ccc(C)cn23)s1 +COc1cc2c(c(Cl)c1O)C(C(C)(C)CO)NCC2 +Cc1ccc(NC(=O)c2ccc3oc(=O)n(C)c3c2)cc1C +CCCCN(C)C(=O)CN1CC(C)Oc2cccc(N)c21 +CC(Nc1cnn(C(C)(C)C)c1)c1ccc(S(C)(=O)=O)cc1 +NS(=O)(=O)c1ccc(NC(=O)N2CCCCC2CCO)cc1 +CCc1ccc(S(=O)(=O)N2CC(C(N)=O)c3ccccc32)s1 +Cc1cc(C(=O)N2CCCC2CC(=O)c2ccccc2)c(C)s1 +CC(=O)Nc1cccc(OC(=O)c2ccc(OCC(F)F)nc2)c1 +O=C(COc1ccccc1Cl)NCc1ccco1 +Cn1nc(C(=O)NCCN2CCOCC2)cc1NC(=O)c1ccco1 +CN(CC(O)C1CC1)C(=O)c1cnc(-c2ccccc2Cl)s1 +COC(=O)C1(NC(=O)Cn2cccnc2=O)CCCC1 +Cc1cc(C)cc(OCC(=O)OCC(=O)NC(C)C)c1 +O=C1CN(C(=O)CCc2ccc(F)cc2)c2ccccc2N1 +CN(Cc1csc2ccccc12)C(=O)c1ccc2[nH]cnc2c1 +CC(=O)c1cc(Br)c2c(c1)NC(=O)C(C)O2 +COC(=O)N=c1[nH]c2ccc(C(O)c3ccc(F)cc3)cc2[nH]1 +COc1cccc2c1OCC(CNC(=O)CCc1c(C)noc1C)C2 +CC(NC(=O)Nc1cnn(C)c1)c1ccc(Cl)cc1 +Cc1ccc(C(=O)c2ccccc2C(=O)N(CC(N)=O)C(C)C)cc1 +Cn1cnc(CNC(=O)c2[nH]c3ccc(Cl)cc3c2Cl)n1 +Cc1ccc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)c(Cl)c1 +Cc1nc(SCc2cc(=O)n3ccsc3n2)c2ccccc2n1 +Cc1cc(C(=O)N2CC3COCC3(COCC3CC3)C2)sc1C +COc1ccc(CNS(=O)(=O)c2cc(OC)ccc2OC)cc1 +CN(C)C(=O)COC(=O)c1cc(-c2cccs2)nc2ccccc12 +O=C(c1cc(F)ccc1O)N1CCC(OCc2ccccc2)CC1 +Cc1nc2ccc(C(=O)N(C)C3CCC(C)CC3)cc2nc1C +CC(C)n1nccc1NC(=O)CSc1ncn(-c2ccccc2)n1 +O=C(c1ccco1)N1CCC2OCCCC2(COCC2CCC2)C1 +O=C(CCc1ccc(-c2ccccc2)o1)NCc1cscn1 +CS(=O)c1cc(OCc2ccccc2)ccc1O +Cc1nc(CC2OCC3CN(C(=O)c4ccc(C)s4)CCC32)n[nH]1 +C=CCNC(=O)Cc1csc(NC(=O)C2CCC(=O)N2)n1 +CC(C)c1cc(C(=O)Nc2cccc(C#N)c2)nc2ccnn12 +CC(C)n1ccc(C(=O)NCCNc2ccc3ccccc3n2)n1 +CC(=O)N1CC2CCC(C1)N(C(=O)c1ccc(C)cc1)C2 +CCOc1cc2c(cc1CNC(=O)Cn1cccnc1=O)OC(C)C2 +CC(=O)c1nn(-c2ccc(F)cc2)nc1NC1CCc2ccccc21 +Cc1csc(SCCC(=O)Nc2ccccc2C)n1 +COC(=O)C1CCCC1NC(=O)Nc1cccc(F)c1F +CC(Nc1nc2ccccc2n2cnnc12)c1ccccc1 +CCN(CC)c1ccc(C(=O)NCc2noc(C(C)C)n2)cn1 +Cc1sc(=O)n(CC(=O)NC(C)Cn2cncn2)c1C +CCN(CC)S(=O)(=O)c1ccc(C)c(NC(=O)c2ccncc2)c1 +Cc1cc(OCC(=O)Nc2cccc(C#N)c2)nnc1C +O=C(Nc1ccccc1)C1CCCN(c2ccc(-n3cncn3)nn2)C1 +CC(NC(=O)Cn1nnc2ccccc2c1=O)c1cccs1 +CC(=O)c1cccc(OCC(=O)NCc2ccccc2C)c1 +Cc1sc2c(c1C)C1=NS(=O)(=O)CCN1C=N2 +COc1ccc(OC)c2c1CN(c1nc3ccccc3o1)CC2O +COC(=O)c1cc(NCc2ccc(F)cc2F)c(OC)c(OC)c1 +CC(=O)c1ccc(NC(=O)CSc2ccc(C#N)cc2)cc1 +O=C(CCn1cncn1)N1CCCC(COc2ccc(F)cc2)C1 +Cn1cnc(CNC(=O)NCC2(c3ccccc3Cl)CCC2)n1 +CCCCc1noc(C2CCCN(C(=O)CCc3cnn(C)c3)C2)n1 +CC(O)CNC(=O)CN1C(=O)COc2cc(Br)ccc21 +OC(Cn1ccnc1-c1cc(F)ccc1-n1cccn1)c1ccccc1 +CCS(=O)(=O)Nc1ccc2sc(NC(C)=O)nc2c1 +CCCC(=O)N1CCC(C(=O)Nc2ccc(NC(N)=O)cc2)CC1 +CC(C)c1ccccc1OCCC(=O)N1CCOCC1C1CC1 +O=C1CCCc2[nH]c(=O)c(C(=O)NCc3cccc4ccccc34)cc21 +CC(C)(C)OC(=O)NCCCC(=O)Nc1ccc(Cl)c(F)c1 +CC1Oc2ccc(NC(=O)c3cccc(Cl)c3)cc2NC1=O +Nc1ccc2c(c1)CCN2C(=O)c1ccccc1Cl +COCc1nn(-c2ccccc2)c(N)c1-c1ccccc1OC +C=CCNc1oc(COc2cccc(Cl)c2)nc1C#N +CCCNC(=O)c1ccc(OCC(C)C)c(N)c1 +CNS(=O)(=O)c1cc(C(=O)NC(C)COC)cc(C)c1C +CC(=O)Nc1nc2ccc(CCC(=O)NC3CCCCC3)cc2s1 +CC(O)CNC(=O)CCSc1ccccc1Br +CNC(=O)COc1cccc(C(=O)NCc2ccccc2)c1 +O=C(Cn1cnc(C2CCC2)cc1=O)NC(C1CC1)C1CC1 +CCSc1nnc(-c2ccc(OC)cc2OC)n1N +O=c1n(CCOc2c(Cl)cccc2Cl)nc2ccccn12 +COCCOc1ccc(-c2noc(C3CCCO3)n2)cc1 +Cc1cccc(N2CCN(CCNC(=O)c3cnc(C)s3)CC2)c1 +Cc1noc(C2CN(C(=O)CC3CCCCC3)C2)n1 +CC(C1CC1)N(C(=O)Cn1cc(C(F)(F)F)ccc1=O)C1CC1 +CCc1noc(CC)c1CNC(=O)c1cccc(OC)c1 +CCn1nnc2cc(C(=O)Nc3cc(F)c(OC)c(F)c3)ccc21 +CCOc1cc(F)ccc1NC(=O)c1ccc(=O)n(C)n1 +CC(C)C(=O)NCCNC(=O)Nc1cccnc1-n1cncn1 +NC(=O)C1CCCN1C(=O)CCCn1nnc2ccccc2c1=O +Cc1nc(-c2ccccn2)n(Cc2csc(-c3ccoc3)n2)n1 +CC(C)(C)c1cnc(CNc2cc(S(C)(=O)=O)ccc2F)o1 +CCc1ccc(C(=O)Nc2ncc(C(N)=O)cc2Cl)o1 +Cc1ccc(NC(=O)c2cc3c([nH]c2=O)CCCC3=O)cc1Cl +CC(C(=O)Nc1nccs1)N1Cc2ccccc2C1=O +CCCN(CCC)C(=O)c1ccc(=O)n(Cc2ccccc2)n1 +CCS(=O)(=O)c1noc(C(=O)NCCCOC)c1N +COCCN1CC2CN(Cc3cccc(OC)n3)CCN2C1=O +Cc1ccccc1-c1nnn(CC(=O)Nc2ccc(F)c(Cl)c2)n1 +Cc1noc(C)c1C(C)NC(=O)Nc1ccc(N2CCOC2=O)cc1 +Clc1cccc(NCc2cnn3ccccc23)c1 +O=C(Nc1ccccc1F)c1nc2c(s1)COCC2 +Cc1c(N)cccc1NC(=O)COC(C)CC(C)C +CCOCC1CCCN(C(=O)c2cc3ccccc3[nH]2)C1 +COc1ccc(Br)cc1C(=O)C1(C)CC1 +CS(=O)(=O)c1cccc(C(=O)N2CCc3ccccc3C2)c1 +C=CCN(C(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1)c1ccccc1 +CCC(=O)N1CCN(Cc2nnnn2-c2ccc(C)cc2)CC1 +COc1cccc(NC(=O)CN2CCN(c3ccc(F)cc3)C2=O)c1 +N#CCc1noc(Cc2c(F)cccc2Cl)n1 +CC(C)C1(C)NC(c2ccccc2Cl)=NC1=O +COc1cc(C)sc1C(=O)NCc1ccc(N2CCCC2=O)cc1 +COc1ccccc1C(=O)Nc1ccc(-c2nc(C)cc(=O)[nH]2)cc1 +CC(C)CNC(=O)C1CCC(=O)N(C)C1c1cccc(F)c1 +NC(=O)Cc1ccc(NC(=O)CCNc2ccccc2)cc1 +CCc1c(C(=O)OC2CCOC2)nnn1-c1cccc(Cl)c1 +CC(C)(C)C(=O)NCCC(=O)NCc1nc(C(C)(C)C)cs1 +CCn1cnnc1C1CCN(C(=O)c2cc3ccccc3o2)CC1 +CC(C)(C)C(O)CN1CCN(C(=O)CCCc2ccccn2)CC1 +COc1ccc(OC)c(C(=O)CCNc2ccc(C#N)cc2)c1 +O=C(COc1ccc(F)c(Cl)c1)NCc1ccncc1 +O=C(Cc1ccc(Br)cc1)N1CCOc2ccncc21 +CC(=O)N1CCc2cc(S(=O)(=O)Nc3cc(C)cc(C)c3)ccc21 +O=C(c1ccc(-n2ccnn2)cc1)N1CCCC1C1CCC1 +Cc1ccc(CNc2c(C#N)nnc3ccccc23)o1 +CC1CN(CCC(=O)Nc2ccc(F)c(F)c2)CC(C)O1 +CCCCNC(=O)c1cn(C2CC2)c2cccc(N)c2c1=O +COCC1COCCC12CCN(C(=O)c1ccn(C)n1)CC2 +COCCCNC(=O)N1CCCC(c2n[nH]c(-c3ccccc3)n2)C1 +Cc1cccc(CN2Cc3[nH]nc(COCCO)c3C2)n1 +COc1ccc2c(c1)c1ncnc(N3CCCC(C)C3)c1n2C +CC(=O)Nc1cccc(NC(=O)N(C)Cc2ccccc2C)c1 +COCc1noc(CN2CCN(C(=O)c3cc(Cl)c[nH]3)CC2)n1 +CCc1ccc(NC(=O)C(C)N2CCN(c3ncccn3)CC2)cc1 +CC(C)NC(=O)Nc1ccccc1C(=O)N1CCC2(CC1)OCCO2 +COc1cc(Cl)c(CNC(=O)NC2CCCCC2)cc1OC +C=CCOc1cccc(NC(=O)c2ccsc2)c1 +OC1(C(F)(F)F)CCN(Cc2nc(-c3ccccc3)cs2)C1 +O=C(CCC1NC(=O)c2ccccc2NC1=O)Nc1nc[nH]n1 +Cc1nc2ccccc2n1CCCOC(=O)c1ccccc1F +CC(C)OC(=O)C(C)CNC(=O)Cc1ccc(F)cc1F +Cc1nn(C)c(C)c1C(=O)Nc1ccc(CC(=O)NC(C)C)cc1 +CCCNC(=O)c1ccc(CS(=O)(=O)N2CCN(C)CC2)cc1 +CC(Oc1ccccc1)C(=O)N(C)CCc1ccccn1 +CCCn1ccnc1C1CC(=O)Nc2cc(O)c(OC)cc21 +Cc1cnc(CCNC(=O)Cc2csc(-c3ccccn3)n2)s1 +Cc1nc(NCCSc2nccn2C)c2nc(C)oc2n1 +COc1cccc(S(=O)(=O)NCC(O)c2ccsc2)c1 +CCn1cnnc1CNC(=O)NCc1ccccc1 +O=C(NCCNC(=O)C1CCCCC1C(F)(F)F)c1cccnc1 +CCN1C(=O)c2ccccc2NC1(C)c1cccc(OC)c1 +CCS(=O)(=O)NCCCNC(=O)c1occc1C +CCOc1ccc(C(=O)Nc2nc(C)cs2)c(OCC)c1 +CC(C)N(C)c1ccc(NC(=O)CSc2ccncc2)cc1F +N#CC(C(=O)c1csc2c1CCCC2)c1nc2ccccc2c(=O)[nH]1 +CC1CCCCN1C(=O)CN1CCN(c2ccccc2Cl)CC1 +O=C1CC(C(=O)NCc2ccnc(OC3CCC3)c2)CN1 +Cc1ccnc2nc(C(=O)NC3(C)CCC(C)CC3)nn12 +Cc1cccnc1NC(=O)NCc1noc2ccccc12 +O=C(CCC(=O)c1ccc(F)cc1)NCc1ccc2c(c1)OCO2 +Cn1cc(NC(=O)NCc2ccc(OCc3ccccn3)cc2)cn1 +O=C(CCc1ccccc1O)Nc1ccn(-c2ncccc2Cl)n1 +O=C(Nc1nc(-c2cccs2)ns1)c1ccc(F)cc1 +Cc1cccc2nc(CNC(=O)c3cn(C4CCCCC4)nn3)cn12 +Cc1ccc(NC(=O)C2CCN(c3cnccn3)CC2)c(Cl)c1 +Cc1ccnc(Nc2nc(C)c(C(=O)N3CCOCC3)s2)c1 +COCC(C)Nc1ncnc(Nc2cccc(Cl)c2C)c1N +CCC(=O)Nc1ccccc1C(=O)Nc1ccc(Cl)cn1 +CCn1c2cc(C)oc2c2cnn(CC(=O)N3CCOCC3)c(=O)c21 +CSc1c(F)cc(NC(=O)NCCc2ccccn2)cc1F +Nc1ccc2c(c1)N(CCOc1cccc(F)c1)CCC2 +CCC(=O)N1CCN(C(=O)C2COc3ccccc3O2)CC1 +Cc1ccccc1CNC(=O)c1ccc(=O)n(C)n1 +Cc1cc(Cc2c(O)n[nH]c2N)ccc1OC(C)C +CCN(Cc1ccco1)C(=O)NCc1cnn(C)c1 +CCn1ccc(C(=O)Nc2sc3c(c2C#N)CCCC3)n1 +CNc1snc(C)c1C(=O)OCc1nc2ccccc2nc1C +Brc1ccccc1-c1csc(N2CCOCC2)n1 +CC1CCN2c3ccccc3CC3(C(=O)CCCC3=O)C2C1 +Cc1cc(N)nc(SCc2ccc(C#N)cc2)n1 +CN(C)S(=O)(=O)N(Cc1ccccc1)c1ccccc1 +Cn1c(SCC(=O)N2CCOCC2)nnc1-c1cccnc1 +CN(Cc1cccc(F)c1)C(=O)Nn1cnc2ccccc21 +CS(=O)(=O)c1ccc(NC(=O)C2(c3ccccc3)CC2)cc1Cl +COc1cccc(C(=O)N(CCC#N)c2ccc(C)cc2)c1 +CCN(CC)C(=O)CN1CCN(C(=O)Nc2cccc(OC)c2)CC1 +CC(=O)Oc1cccc(C(=O)Nc2ccc3c(c2)OCCO3)c1 +COCC(=O)N1CCCC(c2nc3ccccc3s2)C1 +CCn1c2c(ccc1=O)CC(NC(=O)c1cscn1)CC2 +COc1ccc(Cl)cc1C(=O)Nc1cnn(CC(F)(F)F)c1 +CC(C)(CNC(=O)c1cc(Br)c[nH]1)c1ccncc1 +O=C(NCc1cccnc1)Nc1ccccc1C(F)(F)F +Cc1cc(NC(=O)Cn2nnn(-c3cccs3)c2=O)n(C)n1 +O=C(Cn1ncc2ccccc2c1=O)NC1CCCC1 +O=C(CNc1ccccc1C(=O)N1CCOCC1)NC1CC1 +Cc1ccc(C)c(C(=O)Nc2c(C)ccc(N)c2C)c1 +CC(C)(C)c1nc(CN2CCN(c3ccccc3O)CC2)no1 +COc1ccc(S(=O)(=O)Nc2cc(C)ccc2F)c(OC)c1 +Cc1noc(C)c1CN(C)C(=O)c1csc(CC(C)C)n1 +O=C(NCCOCC(F)(F)F)NC1CCCC1 +CCN(CC1CCCO1)C(=O)Cc1cc(Cl)ccc1OC +COc1ccc(CCNC(=O)Cc2ccc(C)cc2)cc1OC +CCOC(=O)c1csc(NC(=O)c2ccc(=O)n(CC)n2)n1 +CCCc1nnc(NC(=O)c2sc(C)nc2C)s1 +CCOc1cc(NCc2ccccc2)nc(CC)n1 +O=C(Nc1cccc2c1OCCO2)NC(CCCO)c1ccccc1 +Cc1ccc2ncc(C(=O)NC3(c4noc(C)n4)CCC3)n2c1 +O=C(NC1CCCCC1)C1CCCN1C(=O)Nc1cccc(F)c1 +COc1ccc(-c2noc(-c3cccc(OCC(N)=O)c3)n2)cc1 +CC(C)CNC(=O)c1sccc1S(=O)(=O)N1CCCCC1 +Cc1ncsc1C(=O)N(Cc1cccnc1)c1ccc(Cl)cc1 +Cc1n[nH]cc1CNC(=O)c1sccc1-n1cnnn1 +O=C(NCC(O)c1ccsc1)c1ccc(F)cc1Cl +CCCCCNC(=O)C1CCC(=O)N1C1OC(=O)c2ccccc21 +Cc1csc2nc(CSc3ncnc4ccccc34)cc(=O)n12 +Cc1nc(NC(=O)CCn2cncn2)sc1-c1ccccn1 +CC(CCC(C)(C)C)NC(=O)NCc1nnc2ccccn12 +CC(=O)Nc1ccc(CN(C)Cc2nc3ccccc3n2C)cc1 +O=C(CNC(=O)c1cccs1)OCc1c(F)cccc1Cl +CNc1nc2ccc(S(=O)(=O)C(C)C)cc2s1 +CCOC(=O)NC1CCN(C(=O)c2cc(C)no2)CC1 +Cn1c(CNC(=O)c2cncc(Br)c2)nc2ccccc21 +Clc1ccc(-c2nc3sc4c(n3n2)CCNC4)cc1 +O=C(Cn1c(-c2ncccn2)noc1=O)NCc1ccccc1F +COc1cc2ncnc(NCCNC(C)=O)c2cc1OC +Cc1ccc(NC(=O)C(O)c2ccc(F)c(C)c2)cc1 +O=c1cnn2c(=O)c(=Cc3ccccc3Cl)sc2n1 +Cc1ccc2c(C)c(CCC(=O)OC(C)C(N)=O)c(=O)oc2c1 +CNC(=O)c1cnc(C=Cc2cccc(F)c2F)s1 +O=C(COC(=O)C1=NC=CC1)Nc1ccc(F)cc1Cl +N#Cc1ccc(Cn2c(=O)oc3cc(CO)ccc32)cc1 +COc1cc(CNC(=O)NCC2COc3ccccc3O2)ccc1O +CC(C)NC(=O)Cc1ccc(NC(=O)c2cc3cccn3cn2)cc1 +CCN(CC)C(=O)c1onc(S(=O)(=O)CC)c1N +CCCOC(=O)c1ccc(Cn2nnc(C(N)=O)c2C)cc1 +Cc1nc(-c2ccncc2)[nH]c(=O)c1CC(=O)NCC1CCCOC1 +O=C(Nc1cn[nH]c1)N1CCN(CCSc2ccccc2)CC1 +CN(C)C(=O)Cn1cnc(NC(=O)c2ccc(-n3ccnn3)cc2)n1 +CC1(CCNC(=O)NCCc2ccccc2Cl)OCCO1 +COc1ccc(N2CC(NC(=O)N3CCC(C)CC3)CC2=O)cc1 +Cn1nc(-c2ccc(NC(=O)C3CC3)cc2)ccc1=O +Cc1c(C(=O)NCC(C)(O)c2ccc(F)cc2F)cnn1C +O=C(Cc1ccc2c(c1)OCCO2)N1CCSc2ccccc21 +O=C(c1ccc(F)cc1)N1CCN(Cc2nccn2C(F)F)CC1 +N#Cc1nnn(-c2ccccc2)c1-c1ccc(F)c(F)c1F +CC(=O)Nc1cccc(OCC#CCNC(=O)C2CC2)c1 +Cc1cc(NC(=O)CCSc2ccccn2)c2ncccc2c1 +CC(NC(=O)c1cn2c3c(cccc3c1=O)CC2)c1ccccc1 +O=C(Nc1ccc2c(N3CCOCC3)ncnc2c1)C1CCCCC1 +CCOC(=O)Cn1c(-c2ccn(C)n2)nc2ccccc21 +CCC(=O)c1cc2c(cc1NC(=O)Cc1ccccc1)OCCO2 +Cc1ccc(-c2nn(-c3ccc(F)cc3)cc2C(=O)NCCO)cc1 +CC(OC(=O)c1cc2sccc2n1C)C(=O)NCC1CCCO1 +COC(=O)CCCNC(=O)C1CC(=O)N(c2cccc(Cl)c2)C1 +COCCN(Cc1cccs1)C(=O)c1ccc(C)o1 +CC1CCCN(C(=O)C2CCN(c3ccc(C#N)cc3F)CC2)C1 +CNC(=O)C(C)(C)CNC(=O)Nc1cc(F)ccc1OC +Nc1ccc2c(c1)N(C(=O)c1ccccc1Cl)CC2 +C#CCNC(=O)CSc1nc(C)nc2sc(C)c(C)c12 +Cc1noc(CN2CCN(CC(=O)c3cc(C)[nH]c3C)CC2)n1 +O=C(NCC1CC1)c1cnn(-c2ccc(Cl)cc2)c1C(F)(F)F +Cc1cc(C)cc(C(=O)NC(C)C(=O)N=c2[nH]c3ccccc3[nH]2)c1 +COCCCNC(=O)N1CCCc2cc(OC)ccc2C1 +COc1ccccc1NC1CCN(C(=O)Cc2ccc(C)nc2)CC1 +Cc1cc(C)n2nc(CC(=O)Nc3cccc4c3CCCC4)nc2n1 +CC(C)c1nc(C2CCCN2C(=O)Cc2cccs2)no1 +Cc1cccc(C)c1N1CCN(C(=O)N2CCOCC2)CC1 +Cc1cccc(NC(=O)Cc2cccc(N)c2)c1C +CSc1ccc(C(O)CNC(=O)c2ccccc2C)cc1 +Cc1cccc(NS(=O)(=O)c2ccc(C)c(C(=O)NC(C)C)c2)c1 +CN1CCN(C(=O)Cn2c(-c3cccs3)cc3cccnc32)CC1 +O=C(CNC(=O)c1ccccc1)NC1CCCCC1 +Cn1nc2n(c1=O)CCN(CC(=O)NCCc1ccccc1)C2 +Cc1cc(NC(=O)c2cccnc2)nn1Cc1ccccc1 +Cc1cc(C)cc(N(C)C(=O)Cn2cccnc2=O)c1 +CC(c1ccc(Cl)cc1Cl)N(C)C(=O)NCC1COCCO1 +CC(C(=O)NCC1CCCO1)n1nnc2ccccc2c1=O +O=C(Nc1ccc2c(c1)COC2)c1ccnc(F)c1 +Cc1cccc(N(C)C(=O)c2cccc(Cn3nc(C)cc3C)c2)n1 +O=C(COC(=O)c1cccnc1SC(F)F)NC1CC1 +CS(=O)(=O)N1CCCN(C(=O)C2CCCO2)CC1 +CC(C)c1nsc(NC2CCN(C3CCOCC3)C2=O)n1 +N#CCCN(CCC#N)Cc1coc(-c2c(F)cccc2F)n1 +Cc1nc(SC(C)C(=O)NCC(C)C)c2c(C)c(C)sc2n1 +O=C(C=C(C1CC1)C1CC1)OCc1cnn(-c2ccccc2)n1 +CN(C)C(=O)c1ccc(COc2ccc(F)cc2)cc1 +Cc1occc1C(=O)NCCOc1ccc(Br)cc1 +Cc1ccc(OCC2COC3CN(Cc4cccs4)CC23)cn1 +COC(=O)c1c(-c2ccc(Cl)cc2)noc1NCc1ccc(C)o1 +CC(c1ccc(-n2cncn2)cc1)N(C)c1ncnc2c1cnn2C +Nc1nccnc1C(=O)Nc1ccc(F)c(Br)c1 +Cc1cccc(OCC(=O)OCCN2CCCC2=O)c1 +CCOC(=O)Nc1ccc(NC(=O)C(CC)OC)cc1 +CC(C)CN1CC(C(=O)NCCOc2ccccc2)CC1=O +COc1ccc(Cl)cc1NC(=O)C(O)c1ccc(C)cc1 +CC(C)OCCCNS(=O)(=O)c1cccc(Cl)c1Cl +COCCOc1ccc(C(=O)N(C)c2ccccc2)cc1 +COc1ccc(C(=O)N2CCCC2C(=O)N(C)C)c(F)c1 +Nc1ccc(-c2cc(Cl)ccc2Cl)n(C2CC2)c1=O +CCN(Cc1ccccc1)C(=O)COc1ccccc1F +CCNC(=O)COc1cccc(NC2CCCOC2)c1 +O=C(NCCc1c[nH]c2ccccc12)c1ccc(-c2nnco2)cc1 +CCC(C)NC(=O)NCC(=O)NCc1ccco1 +COc1ccc(OC)c(C(=O)Nc2ccccc2C(C)=O)c1 +NC(=O)NCCCCC(=O)Nc1ccccc1N1CCCCC1 +CN(C)C(=O)NCC1CC12CCN(C(=O)c1ccco1)CC2 +CC(C)CC(C(=O)NC1C2CCOC2C1(C)C)N1CCCCC1=O +CCc1cc(C(=O)Nc2c(C(=O)N(C)C)nn(C)c2C)n(C)n1 +CC(C)c1cccc(NC(=O)NCC(=O)N2CCCCC2)c1 +CCCc1ccccc1NC(=O)c1cccc(OCC(N)=O)c1 +C#CCN(Cc1ccc(F)cc1)Cc1ccc(C(=O)N(C)C)[nH]1 +Cc1cnc(C(=O)OCC(=O)Nc2ccc3c(c2)OCCCO3)cn1 +CC(Oc1cc(Cl)cc(Cl)c1)C(=O)N(C)CC(O)C1CC1 +O=C(CCNS(=O)(=O)c1cccnc1)NCc1cccs1 +CCN(C(=O)Cc1c(C)nc2c(c1C)c(=O)[nH]n2C)C1CCCC1 +O=C(NCCc1ccccn1)C1COCC(=O)N1Cc1ccccc1 +COCCNC1=NS(=O)(=O)c2c(Cl)cc(Cl)cc2N1 +COC(=O)C1CCN(Cc2ccccc2C#N)CC1 +COc1cc(OC)cc(C(=O)OCC(=O)c2ccc(O)cc2O)c1 +COCC(O)CN(C)C(=O)c1cccnc1OC +CNC(=O)Nc1ccccc1OCC1CCCCO1 +CCC(C)n1c(C)cn2c3c(=O)[nH]c(=O)n(C)c3nc12 +CCn1cc(-c2cc(CO)c3ccccc3n2)cn1 +O=C(Nc1nnc(-c2ccncc2)s1)c1cccc2ccccc12 +CCS(=O)(=O)NCC(C)(C)c1ccc2c(c1)OCO2 +Cc1nc(N2CCC(Oc3cccc(F)c3)CC2)c2c(C)noc2n1 +COCc1[nH]nc(C)c1-c1cccc(C(C)OC)c1 +CCc1noc(CC)c1CC(=O)NCc1ccc(F)c(Cl)c1 +O=C1CCc2cc(NC(=O)c3ccsc3)ccc2N1 +COC(=O)c1ccc(C(=O)NCCc2ccc(OC)cc2)cn1 +Cc1ccnc(NC(=O)C2(c3ccc4c(c3)OCCO4)CCCC2)c1 +O=C(NC1CC(=O)N(CCc2ccccc2)C1)C1CCC1 +Cc1cc(NC(=O)Cc2noc3ccccc23)n(-c2ccccc2)n1 +CCOCC(=O)Nc1ncn(Cc2cccc(Br)c2)n1 +CCSc1nc2n(n1)C(c1cn(C)nc1C)C(C(=O)OC)=C(C)N2 +CCCCCC(=O)Nc1ccc(C(=O)NCC)cc1 +O=C(NCc1nnc2ccccn12)c1ccc2c(c1)CCC2 +O=C(Nc1ccccn1)c1cncn1-c1ccccc1 +CC1CCCCN1C(=O)c1cc(Br)ccc1F +O=C(NCc1ccccc1CO)c1ccc2c(c1)OCCO2 +Cc1ccc(CNc2ccccc2-n2cccn2)o1 +Cc1ccc(F)c(S(=O)(=O)N(C(C)C)C2CCC2)c1 +CCCOc1ccc(C(=O)NC(C)CC)cc1N +CC(NC(=O)COc1ccc(C(N)=O)cc1)C1CC1 +CCc1ccc(C(=O)OCc2nnnn2-c2ccccc2)cc1 +O=S(=O)(CCc1ccccc1)NCC(O)C1CCCCC1 +Cc1ccccc1-n1cnnc1SCCCc1cnn(C)c1 +COC(=O)CCN(C)S(=O)(=O)c1cn(C)nc1N +CNC(=O)c1csc(Nc2ccc(OC)cc2OC)n1 +CC(C)C(=O)NCCN1CCN(C(=O)c2ccsc2)CC1 +CC(CO)(Cc1ccncc1)c1ccc2c(c1)OCO2 +Cc1ccccc1CC(=O)Nc1cc(F)c(S(C)(=O)=O)c(F)c1 +Cc1nnsc1C(=O)Nc1ccc(-c2cc[nH]n2)cc1 +CC(C)n1cnc(S(=O)(=O)N(C)c2cccc3ncccc23)c1 +COC(=O)NCC(=O)N1CCCC1c1nc(-c2ccccc2F)c[nH]1 +CC(=O)NCC1NCCc2c(C)ccc(Br)c21 +CC(C)n1nccc1NC(=O)COCC1CCCO1 +CC1(NC(=O)NC2CCCn3ncnc32)Cc2ccccc2C1 +Cc1cc(NC(C)C2(C)CC2)ccc1-n1cnnn1 +CCCc1c(C)nn(C(=O)CCC(=O)NCc2ccccc2)c1C +Cc1cccc(NC(=O)CN(C)C(=O)c2cc3ccccc3s2)n1 +O=C(Cn1nnc2ccccc2c1=O)N1CCc2ccccc2C1 +CC1CCC(NC(=O)COC(=O)c2ccccc2C(F)(F)F)CC1 +CCC(C)(NC(=O)Nc1ccc(-c2cc[nH]n2)cc1)c1nccs1 +Cc1ccc(NC(=O)Cn2cc(Cl)cn2)c(N)c1 +Cc1nc(-c2cnn(C)c2)sc1-c1nc(-c2ccc(C#N)cn2)no1 +CC(=O)Nc1ccc(S(=O)(=O)Nc2ccc(F)cc2)cc1Cl +Cc1nc(C(C)(C)NC(=O)c2cc3c([nH]c2=O)CCCC3)sc1C +CCOCc1nn2c(=O)c(NC(=O)c3ccccc3)cnc2s1 +COCCOCCNC(=O)NC1CC(C)(C)Cc2oc(C)cc21 +Cc1cc(=O)n2nc(-c3ccsc3-n3c(C)ccc3C)cc2[nH]1 +O=C(NCc1cn[nH]c1)c1ccc(C#CCCO)s1 +Nc1nc(N)nc(COc2ccc(Cl)cc2)n1 +COCCCCNC(=O)c1cc(=O)c2ccccc2[nH]1 +O=C(Nc1cnc2ccccc2c1)C1CCN(c2cnccn2)CC1 +CC(=O)c1ccc(NC(=O)c2ccc(OC(C)C)nc2)cc1C +Cc1ccccc1SCC(=O)Oc1ccc(C#N)cc1 +O=C(NCCNC(=O)c1ccco1)c1ccc2cnsc2c1 +O=C(CCCOc1ccccc1)Oc1ccc2c(c1)OCO2 +Brc1ccccc1SCc1nnc(C2CC2)o1 +O=C(CCc1csc(-c2ccncc2)n1)Nc1ccccc1 +CC(=O)Nc1cccc(C(C)NCC(C)c2c(C)noc2C)c1 +CC1(C)Oc2ccc(N)cc2N(Cc2ccccc2F)C1=O +CCn1c(-c2ccc3c(c2)OCCO3)ccc(C(C)=O)c1=O +CC(=O)c1ccc(NC(=O)c2cnn(-c3ccccc3)c2)cc1 +Cc1nc(C(=O)NCCN2CCc3ccccc32)cs1 +Cc1nn(CCO)c(C)c1CNc1ccc(C(C)C)cc1 +CCOc1cc(F)ccc1NC(=O)COc1ccc(C(N)=O)cc1 +COc1ccc(Cn2c(N)nnc2SC)cc1 +CC1CCCC(NC(=O)CCNS(C)(=O)=O)C1 +Cc1ccc(CN2C(=O)CCC2C(=O)NCCCN2CCOCC2)o1 +CC1CCC(NC(=O)c2ccc(C(=O)N(C)C)cc2)CC1 +Cc1ccc(OC(C)C(=O)NCc2cccnc2)c(C)c1 +COc1ccnc(N2CC=C(c3c[nH]c4ncccc34)CC2)n1 +O=C(C1CCCCC1)N1CCN(Cc2ccc3ccccc3n2)CC1 +Brc1ccc2[nH]nc(-c3ccc[nH]3)c2c1 +COc1ccc(C(O)CNCc2cccnc2)c(OC)c1 +Cc1ccc(OCC(=O)NCc2csc(C3CC3)n2)cc1 +Cc1ccc(-n2c(=O)c3c4c(sc3n3nnnc23)CCC4)cc1 +O=C(NCc1ccccc1-n1ccnc1)Nc1cc(Cl)ccc1F +N#Cc1nc(-c2ccco2)oc1N1CCC(C(=O)NCCCO)CC1 +COc1ccc(CNc2ccc3c(c2)COC3)c(OC)c1 +CC(NC(=O)CCc1ccc(C#N)cc1)c1cccs1 +COc1ccnc(NC(=O)Cc2ccccc2Cl)c1 +COc1cccc(CN(C)C(=O)Nc2ccccc2F)c1 +NC(=O)c1ccccc1OCC(=O)Nc1ccc(F)c(F)c1 +O=C(COc1ccc2c(c1)OCCO2)NCc1ncc[nH]1 +Cc1ccc(-c2nccn3cc(C(=O)N4CCC(C)CC4)nc23)cc1 +COc1cc(CNC(=O)c2ccc(C(C)C)cc2)ccn1 +CCc1ncnc2c1CCN(C(=O)CCc1ccccc1)CC2 +CCn1c(C(=O)NC(C(=O)OC)C(C)C)cc2sccc21 +Cc1cc(C)n2nc(SCC(=O)N3CCCCC3)nc2n1 +Cc1ccc(C)c(NC(=O)CS(=O)(=O)c2ccccc2)c1 +CN(CC(=O)NC(C)(C)c1cccc(Cl)c1)S(C)(=O)=O +N#Cc1cnn(C(=O)Cn2c(-c3cscn3)nc3ccccc32)c1N +Cc1nc2c(Br)cc(C(F)(F)F)cn2c1C +COCCn1ccc(NCc2ccc(CO)o2)n1 +COc1ccc(CSc2nnc(N)n2C2CC2)cc1F +O=C(Nc1c[nH]nc1-c1ccccc1)c1csc(-c2ccccn2)n1 +CCC(Oc1ccccc1OC)C(=O)Nc1ccccc1F +CC(C)Cc1nnc(NC(=O)CCn2cncn2)s1 +COc1ccc(CNc2cccc(N(C)C)c2)cc1OC +COc1cc(Cl)ccc1C(=O)N(CCC(N)=O)c1ccccc1 +CCC1C(=O)NCCN1Cc1noc(C(C)C)n1 +CCn1c(SCCOC)nc2sc3c(c2c1=O)CCCC3 +CCc1ccc2nc(NC(=O)NCC3CCOCO3)sc2c1 +COc1ccc(-c2nnc(Sc3nc(C)nc4[nH]ccc34)o2)cc1 +NC(=O)c1oc2ccccc2c1NC(=O)c1ccc2c(c1)CCCC2 +O=C(Nc1ccc(-n2cncn2)cc1)NC1c2ccccc2CC1O +COc1cc(C)sc1C(=O)NC(C)c1ccc(-n2cncn2)cc1 +Cc1noc(C)c1C(C)NC(=O)c1ccc(C(=O)N(C)C)cc1 +Cc1cc(NC(=O)N2CCC(n3cncn3)CC2)ccc1F +O=C(CCS(=O)(=O)c1ccccc1)NCC#Cc1ccc(F)cc1 +Cc1nn(C)c(C)c1S(=O)(=O)Nc1ccccc1 +CCCC(C)NC(=O)C(C)N1CCN(C(=O)N(C)C)CC1 +CC1Oc2ccc(NC(=O)c3ccccc3)cc2N(C)C1=O +CNc1nc(C(=O)N(C)Cc2cccc(-n3cccn3)c2)cs1 +Cc1ccc(NC(=O)C(C)Oc2ccccc2)nc1 +CCC1CN(Cc2ccc(OC(C)C(=O)OC)cc2)CC(C)O1 +CCOc1ncccc1CNS(=O)(=O)c1ccc(C#N)cc1 +COC(=O)C(CC(C)C)NC(=O)c1cc(-c2ccccc2)nn1C +CC1CCCN(C(=O)CCc2ccc(Cl)c(N)c2)C1 +OC(CNc1cc(Br)ccc1F)COCC1CC1 +CCCN(CCC)C(=O)CSc1ccc2c(c1)OCCCO2 +O=C(CC1CCCCC1)Nc1cnn(C2CCOCC2)c1 +CCC(=O)c1ccc(OCCn2c(=O)oc3cccnc32)cc1 +O=C(COCc1nc2ccccc2s1)N1CCN(CCO)CC1 +NC(=O)Cc1csc(NC(=O)C2(c3ccccc3)CC2)n1 +Cc1csc(C(C)CNC(=O)Nc2nocc2C)n1 +Cc1ccc(NC(=O)NCCCO)cc1S(C)(=O)=O +Cc1ccccc1N(C(=O)c1cccc(-n2cccn2)n1)C(C)C +CC(=O)Nc1ccc(OCC(=O)Nc2ccc3c(c2)CCC3)cc1 +CCOC(=O)c1ccccc1CN1C(=O)c2ccccc2S1(=O)=O +O=C(Nc1nccs1)c1cccc(N2CCCC2=O)c1 +CCC1CCCN(C(=O)Nc2ccc(C)c(S(=O)(=O)NC)c2)C1 +CC(C)CNC(=O)C1CCCN(C(=O)CCn2cncn2)C1 +N#Cc1ccc(Cn2c(CO)nc3ccccc32)cc1 +COCc1cncc2c1CCN(Cc1ccsc1)C2 +CCNC(=O)c1cc(Cl)ccc1NC(=O)CCCc1ccccn1 +NC(=O)N1CCCC(C(=O)OCc2nc(-c3ccccc3)no2)C1 +O=C(COC(=O)c1cc(=O)[nH]c(=O)[nH]1)NCCC1=CCCCC1 +O=C(c1ccc(OCC(F)F)nc1)N1CCc2cc(F)ccc2C1 +O=C(NCCCN1CCCC1=O)c1c[nH]c2cccc(F)c12 +Cc1ccc(NC(=O)Cc2cn3ccsc3n2)c(C)c1 +Cc1occc1C(=O)Nc1ccnc2c(F)cccc12 +O=C1CCc2cc(S(=O)(=O)N3CCCC3)cc3c2N1CC3 +CC(C)CCNS(=O)(=O)c1cccc2cnccc12 +CC(C)Cc1cc(C(=O)NC(Cc2ccccc2)C(N)=O)on1 +CCOc1ccc(C#N)cc1NC(=O)c1ccc(C)s1 +Cc1ccnn1Cc1nc(C2CCOCC2)nn1C1CCCCC1 +Cc1noc(C)c1COC(=O)c1cccc(CN2CCCC2=O)c1 +CCN(CC)C(=O)c1c(C)nc(-c2ccco2)nc1SC +COC(=O)C1CCN(C(=O)c2csc3c2CCC(C)C3)CC1 +O=C(Nc1ccccc1C(=O)N1CCCCC1)C1CCCO1 +Cc1nn(Cc2nc(-c3ccsc3)no2)c(=O)c2ccccc12 +Cc1cc(C(=O)NCCn2ccc(-c3cccs3)n2)no1 +CCCc1cc(NCCCO)n2c(nc3ccccc32)c1C#N +COc1ccc2c(c1OC)C(C1CCCO1)NCC2 +COCCCNC(=O)NCC(O)c1ccc(F)c(F)c1 +COC(=O)c1cccc(CNC(=O)c2ccon2)c1 +CC(C#N)N(C)C(=O)c1cccc(Br)c1 +CCN(CC1CCCO1)C(=O)Cc1ccc(F)c(F)c1 +CCCCn1nc(C(=O)Nc2c[nH]ccc2=O)c2ccccc2c1=O +Cc1cc2c(=O)c3ccc(Cl)cc3[nH]c2c(C(N)=O)c1C +CCOC(=O)c1ccc(OCC(=O)NC(C)(C)C)cc1 +CCc1ccc(C(=O)NCC(c2ccccc2)N2CCOCC2)cc1 +CC1(C)C(=O)c2ccc(N)cc2N(CCCC#N)C1=O +CCNC(=O)c1ccnc(-c2cccc(C(C)OC)c2)c1 +O=C(NCc1ccco1)C1CCN(Cc2nc3ccccc3[nH]2)CC1 +CCN(Cc1cccs1)C(=O)c1ccc(F)c(COC)c1 +Cc1ccccc1OCCSc1ncnc2[nH]cnc12 +Cc1cc(NC(=O)CCc2nc(-c3cccs3)no2)n(C)n1 +O=C(c1cscn1)N1CC2CCCC2(COCc2ccccn2)C1 +CC1(NC(=O)Nc2ccc(Oc3cccnc3)nc2)CCOC1 +CCc1onc(C)c1NC(=O)N(C)Cc1cc(C)on1 +N#CCOc1ccc(C=Cc2nc(-c3ccc(C#N)cn3)no2)cc1 +CC1(C(=O)NCCCOCC(F)(F)F)Cc2ccccc2C(=O)O1 +O=C(CNC(=O)c1ccc(F)cc1F)NC1CCC(O)CC1 +CCn1nnc2cc(C(=O)Nc3cccc(C)c3C(=O)OC)ccc21 +CCC(=O)N1CCN(Cc2cccc3c2OC(C)(C)C3)CC1 +Cc1noc(C)c1S(=O)(=O)NCCC(=O)NC1CCCCCC1 +Cc1cc(C(=O)OC(C)C(=O)Nc2ncnc3nc[nH]c23)c(C)o1 +COc1ccc(CNC(=O)CCC(=O)c2cc(C)ccc2C)cc1 +C=CCSc1ccccc1NC(=O)c1cnc(C)cn1 +CNc1cc(C2CCN2S(=O)(=O)c2cnn(C)c2)nc(C)n1 +CCOc1ccc(CCC(=O)N2CCC(C(N)=O)CC2)cc1 +COC(=O)c1ccc(CN(C)Cc2csc(C)n2)cc1F +Cc1cc(NC(=O)N2CCN(c3cc(Cl)ccc3C)CC2)n(C)n1 +O=C(Nc1cc(-c2ccc(C(F)(F)F)cc2)no1)c1cc[nH]c(=O)c1 +COc1ccc(CC(=O)N2CCc3ncnc(C)c3CC2)cc1 +CNc1snc(C)c1C(=O)NCc1ccc(OC)nc1 +CC(C)n1cc(Br)cc1C(=O)N(C)CC1CCCCO1 +O=C(CCC1CCCO1)Nc1cccc(-c2nccs2)c1 +COc1cccc(CNC(=O)NCC2(c3ccccc3F)CC2)n1 +O=C(C1CC1)N1CCN(Cc2ccc(OCC(F)(F)F)cc2)CC1 +Cc1cccc2c1CNCC2C(=O)NC1CCCC1 +CCCCN(Cc1cc2cccc(C)c2[nH]c1=O)S(C)(=O)=O +COc1ccc(-c2noc(C(=O)NC(C)(C)CO)n2)cc1OC +CN(C)C(=O)COc1ccc(NC(=O)c2ccccc2Cl)cc1 +Cc1cc(C)c(CNC(=O)Cc2ccc[nH]2)c(C)c1 +COCc1c(CO)nnn1-c1ccc(F)c(Cl)c1 +COc1cccc2c1N(C(=O)c1cnccn1)CCC2 +CCn1cnnc1CNC(=O)c1ccc2ccccc2n1 +Cc1cccc(Oc2ncccc2NC(=O)c2cc[nH]n2)c1C +Nc1ccc(-c2ccc(Br)cc2)nn1 +COC(=O)C(C)(C)NS(=O)(=O)c1cc(F)ccc1C +COC(=O)C1(NCC(F)(F)F)CCCCCC1 +Cc1ccc(C(=O)NC(C)c2ccc(S(C)(=O)=O)cc2)c(O)c1C +Cc1cccc(Cn2nnc(C(=O)Nc3cc(C)cc(C)c3)c2N)c1 +NC(=O)c1ccc(Cl)cc1OS(=O)(=O)c1cccs1 +O=C(CNC(=O)c1ccc2c(c1)NC(=O)C1CCCN21)NC1CC1 +CC(NC(=O)Cc1c[nH]c2ccccc12)c1ccccn1 +COc1ccc(C(=O)Nc2ccc(C#N)cc2)nn1 +COc1ccc(C(=O)Nc2ccc(CC(N)=O)cc2)nn1 +CCN(C(=O)C(C)Sc1nncn1C)c1ccccc1 +CC(C)Cn1cncc1Cn1ccnc1-c1ccc(-c2cc[nH]n2)o1 +COc1cccc(CNC2C(c3cncnc3)CC(O)C2O)c1 +COC(=O)c1ccc(CN(C)Cc2ccc(C)s2)cc1F +Cc1cc(F)ccc1CCNC(=O)NC(C)C(=O)Nc1ccccc1 +COC(=O)c1ccc(OCC(=O)c2ccc3c(c2)OCO3)c(OC)c1 +OCC1NCCc2cc(Br)cc(Cl)c21 +NC(=O)NCCCCC(=O)NC1CCN(c2ccccc2)CC1 +COC(=O)CC1CCCCN1S(=O)(=O)Cc1cc(C)on1 +CCOc1cccc(CCC(=O)Nc2ccc(O)cc2)c1 +CCC1CCCCN1C(=O)Nc1ccc(C(=O)N(C)C)c(C)c1 +COc1cc(Cl)ccc1C(=O)NC(C(N)=O)c1ccccc1 +Cc1cnc(CNC(=O)c2cc(-c3cc[nH]n3)n3ccccc23)cn1 +COC(=O)C(C)Oc1ccc(Cl)cc1C(C)=O +CCN(CC(C)(C)O)C(=O)NC(c1ccncc1)c1ccc(F)cc1 +N#Cc1ccc(CN2C(=O)COc3ccc(O)cc32)cc1 +Cc1nc2ccn(Cc3ccccc3)c(=O)c2cc1C(=O)N1CCCC1 +Cc1cc(C)nc(SCC(=O)Nc2nnc(C)s2)n1 +Cc1n[nH]c(C)c1C(C)CC(=O)NCC(O)Cc1ccccc1 +CC(=O)c1cccc(OCC(=O)NC(c2ccccc2)c2ccco2)c1 +OCc1cnnn1-c1ccc(C(F)(F)F)cc1Cl +FC(F)(F)c1nnnn1C=C1C2CC3CC(C2)CC1C3 +COCCOCC(=O)N1CCCCC1c1ccc(C(F)(F)F)cc1 +CNC(=O)c1cccc(Nc2cnnc3ccc(Cl)cc23)c1 +CCc1nnc(SCC(=O)Nc2cc(Cl)ccc2O)o1 +CCN(CC1CCCO1)C(=O)c1cnn(CC)c1 +CCC(NC(=O)CSc1nccn1C)C(C)C +COCCNC(=O)NCc1cccc(CN2CCOCC2)c1 +CCOC(=O)c1cc(S(=O)(=O)N(C)C)ccc1N1CCCC1 +O=C(c1cn2cccnc2n1)N1CCn2cccc2C1c1ccccc1 +CC(=O)Nc1ccc(NC(=O)c2cc(C)n(C(C)(C)C)n2)c(Cl)c1 +CN(C)S(=O)(=O)c1ccc(Cn2cc(Cl)cn2)o1 +CC1CCCC(CNC(=O)Nc2ccc3c(c2)OCC(=O)N3)C1 +Cc1ccc(C(=O)N2CC(=O)c3ccccc3S2(=O)=O)cc1 +Cc1ccc(Cl)c(OCn2cc(Cl)c(N)n2)c1 +Cc1cccc(NC(=O)Cn2nc(-c3ccccc3)ccc2=O)n1 +COCCNc1ncnc2c1cnn2-c1cccc(C)c1 +N#Cc1ccccc1CSc1nnnn1C1CCCC1 +Cc1cc(NC(=O)c2ccccc2-c2ccccc2)n(C)n1 +CCCCNc1nnc(-c2scnc2COC)s1 +CCOc1ccc(-c2nc(C)c(CC#N)s2)cc1OC +CCCN(CC(F)(F)F)c1ncc(N)cc1C(N)=O +CCn1nnc2c(Nc3cccc(C)c3C)ncnc21 +Cc1ccccc1COC1CCN(C(=O)c2cnn(C)c2)CC1 +O=C(CCCc1ccccc1)N1CCN(C(=O)Cc2ccc[nH]2)CC1 +FC(F)(F)c1ccc(Cl)c(NCc2ccncc2)c1 +CCOC(=O)Cc1c(C)nc2ncnn2c1N1CCCC(C)C1 +CC(NC(=O)CCn1ncc2ccccc21)c1ccccc1 +Cn1cc(C(=O)NCc2nc(-c3ccccc3)no2)nn1 +Cc1n[nH]c(C2CN(CC(=O)Nc3nnc(C)s3)CCO2)n1 +CCC(C)NC(=O)Cn1cnc2sccc2c1=O +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)C(C)OCC1CC1 +N#CCn1cccc(OCc2cccc(F)c2)c1=O +Clc1ccc2c(c1Cl)CCC2Nc1ccc2nnnn2n1 +CC(C)n1cccc1C(=O)N(C)C1(C(N)=O)CCCC1 +COC(=O)c1csc(NC(=O)c2cnc3ccc(C)cn23)c1 +CCc1ccc(NC(=O)C(NC(N)=O)C(C)C)cc1 +CN(C)S(=O)(=O)c1cccc(Cn2ccccc2=O)c1 +O=C(Cc1c[nH]c2ccccc12)N1CCN(C(=O)c2ccncc2)CC1 +COc1cc(CN2CCOC(C)C2C)cc2c1OCO2 +COCCNc1nc2ccccc2n2nc(C(=O)N(C)C)nc12 +Cc1ccsc1CNC(=O)CSc1nnc(C)n1N +Cc1ccc(C2C(C(=O)NC3CC3)CCC(=O)N2C)cc1 +C=CCN(Cc1ccccc1)C(=O)c1cc(N)[nH]n1 +CC(CNC(=O)NC(C)C(C)CO)c1ccc(F)c(F)c1 +Cc1ccc(N2CCCC(c3ccnc(C)n3)C2)nn1 +O=C(NCC(F)(F)F)c1cnc(OCC(F)(F)F)c(Cl)c1 +Cc1ccc(SCC(=O)Nc2cccc(-n3cnnc3)c2)cc1 +Cc1csc(CCCNC(=O)Cc2ccc[nH]2)n1 +C=CC(CC(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1)c1ccccc1 +COc1ccc(NC(=O)Cc2ccc(F)cc2F)cc1 +Cn1c(=NC(=O)CC2CCCO2)[nH]c2cc(Cl)ccc21 +Cc1cccc(CC(=O)NCC2CCN(C(=O)c3ccoc3)CC2)c1 +COc1cncc(CCC(=O)N2CCCc3cccc(F)c32)c1 +COc1ccccc1CN(C1CC1)S(=O)(=O)c1c(C)nn(C)c1C +CCSc1ccc(NC(=O)c2cc(C)n[nH]2)cn1 +CCN(C(=O)c1snc(C#N)c1N)c1ccccc1 +COc1cc2c(cc1O)CCNC2c1ccc(O)c(F)c1 +CC(C)COc1cccc(NC(=O)CNC(=O)c2ccsc2)c1 +CCN(CCC#N)C(=O)CSc1nnnn1-c1ccc(C)cc1C +Cc1ccccc1OCCNS(=O)(=O)c1ccccc1 +COc1cc(C(=O)N=c2[nH]nc3cc(C)ccn23)ccc1OC(F)F +Cc1cnc2c(c1)NC(=O)CN2C(=O)c1csnc1C +CCCn1c(SCC(=O)NCc2ccc(F)cc2)n[nH]c1=O +CCCn1ncc(CNC2COc3ccccc3C2)c1C +CCOC(=O)C(C)(C)N(C)Cc1ccc(C(=O)N(C)C)[nH]1 +O=C(NC1CC1)c1cccc(NC(=O)C2CC=CCC2)c1 +CCOC(=O)c1cnc(SC)nc1NC1CCCC1 +COc1cc(NC(=O)CNc2ccccc2C)cc(OC)c1 +CCCc1sc(C(=O)Nc2c[nH]nc2C)cc1CC +CCOC(=O)C1=C(C)C(C(=O)N2CCCCC2C)=NC1C +Cc1cc(NC(=O)Cn2cnc(N)n2)ccc1Br +COc1ccc(C2OC(=O)C(C)(C)C(=O)C2(C)C)cc1 +C=CCNC(=O)C1CCCN(c2ncnc3oc(C)c(C)c23)C1 +CCc1cccc(CC)c1NC(=O)Cn1cc(Cl)cn1 +CC(C)(C)c1csc(NC(=O)CN2CCCCC2=O)n1 +Cc1[nH]c(NCc2ccc(F)cc2N)c(C#N)c1C +CCCC(=O)NCC(=O)N1CCCCCC1CC(C)C +CN(C)C(CNC(=O)c1ccc2ccccc2n1)c1cccs1 +CCc1ncc(C(=O)NCc2nc3cc(OC)ccc3o2)cn1 +Cc1ccc(NC(=O)C(CC(C)C)N2CCCCC2=O)nc1 +CCN(CC)S(=O)(=O)NCCc1ccc(Cl)cc1 +CS(=O)(=O)NCCn1c(CO)nc2cc(N)ccc21 +CCC1c2ccsc2CCN1Cc1scnc1C +CCC(C)C(=O)Nc1cccc(N2CCCC2=O)c1 +CC(NC(N)=O)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 +COc1cc(Br)c(NC(=O)C2CCCO2)cc1OC +CCc1nccn1-c1ccc(CNC(=O)C2CCCO2)cc1 +CC1CCN(C(=O)C(C)NC(C)c2ccc3c(c2)CC(=O)N3)CC1 +CCOC(=O)CCn1cc(CO)c2cccc(C)c21 +Cc1cc(Cl)ccc1OCCCC(=O)N(C)CC(N)=O +CN(Cc1ccc2nonc2c1)C(=O)C1CCCCn2nnnc21 +CC(C)C(CNC(=O)NC1CCCCC1C)N1CCOCC1 +NC(=O)c1ccc(NC(c2ccccc2)c2ccco2)cc1 +CCCCC(=O)N1CCC(c2nnc(CC)s2)CC1 +CC(=O)c1ccc(NC(=O)Nc2cnn(CC3CCCO3)c2)cc1C +NC(=O)c1cc(N2CCC(n3cncn3)CC2)nc2ccccc12 +CC(C)c1nnc(NC(=O)Nc2cnn(CCO)c2)s1 +CC(C)c1n[nH]c(C2CN(C(=O)CCc3ccco3)CCO2)n1 +CCN(Cc1cnc2ccccn12)C(=O)c1cccc2ccccc12 +Fc1ccc(-c2noc(CSc3nnc4n3CCCCC4)n2)cc1 +O=C(C1CC1(Cl)Cl)N1CCOC2CCCCC21 +Cc1cc(S(=O)(=O)NCc2ncoc2-c2ccccc2)ccc1F +CNS(=O)(=O)c1cc(NCc2cccs2)ccc1C +CC(C)c1nnc(NC(=O)N(C)C(C)c2ccccc2F)s1 +N#Cc1cccc(CNc2cccc(F)c2C#N)c1 +Cn1ccc(NC(=O)CCn2c(=O)oc3ccccc32)n1 +CC(C)(C)c1ccc(N2CCN(CCO)CC2)cc1 +CC(CC(=O)c1ccco1)NC(=O)Cc1ccc(-n2cnnn2)cc1 +CC(C)C(CCO)NC(=O)NCc1cccc(C#N)c1 +CCOc1ccc(S(=O)(=O)Nc2ccc(N)cc2C)cc1 +Cc1ccc(-n2nnnc2N2CCC(n3cncn3)CC2)cc1 +O=C(Nc1ccc(OC(F)(F)F)cc1)C1CC(O)=Nc2nncn21 +CCC(Oc1ccccc1)C(=O)NCc1ccc(OC)cc1 +COc1cc(-c2cnnn2-c2nonc2N)cc(OC)c1OC +COC1CCN(C(=O)c2ccc3c(c2)OCCCO3)C2CCOC12 +Cc1nc(CNC(=O)C(C)CCc2cccc(F)c2)c(C)s1 +CN(C)C(=O)c1ccc(CNC(=O)Nc2cc(F)ccc2F)cc1 +COc1ccc(OCC(=O)NCc2cccc(C)c2)cc1 +Cc1cc(NC(=O)CSc2nccn2C)n(-c2ccccc2)n1 +CCOC(=O)c1cccc(COc2ccccc2)n1 +CCS(=O)(=O)N1Cc2nccn2CC(Cn2cccn2)C1 +COc1ccc2c(c1)nc(C#N)n2-c1ccncc1 +CCn1ccnc1N1CCN(C(=O)c2c(F)cccc2Cl)CC1 +CC(NC(=O)CCc1cccnc1)c1ccc(S(C)(=O)=O)cc1 +CC(=O)NC1C(c2ccc(C(F)(F)F)nc2)CC(O)C1O +Cc1cn(-c2ccccc2Cl)nc1NCc1cc(C#N)n(C)c1C +CC(=O)NCCNC(=O)NCc1ccc(-c2ccn[nH]2)cc1 +CCC1c2ccccc2CCN1C(=O)c1c[nH]c(C)cc1=O +COc1cc(C)c(S(=O)(=O)N(C2CC2)C(C)C2CC2)cc1OC +Cc1sc2ncnc(SC(C)C(N)=O)c2c1C +CC(C)C(=O)c1ccccc1NC(=O)Cn1ncc2ccccc2c1=O +NC(=O)c1ccc(=O)n(Cc2cccc(C(F)(F)F)c2)n1 +OCc1cc(-c2ccc(-c3ccn[nH]3)cc2)ccn1 +OC(c1ccccc1Cl)C1NCCc2cc(F)ccc21 +Cc1cc(C(=O)NCC(=O)Nc2nccs2)c(C)o1 +CSc1cccc(C(=O)Nc2nnc(-c3ccn(C)n3)o2)c1 +COc1cc(C)ccc1OCC(=O)Nc1cccc(F)c1 +COc1ccc(OC)c(CN(C(=O)c2ccc(F)c(F)c2)C2CC2)c1 +CSc1nc2ccccc2c(NCC(O)c2ccccc2)c1C#N +COc1cccc(CSc2nc(N)c(C#N)cc2C#N)c1 +CCC(C)NC(=O)Nc1cc(-c2ncco2)ccc1C +O=C(CCC1Cc2ccccc2NC1=O)NCCNc1ncccn1 +COCCNC(=O)NC1CC(=O)N(c2ccc(OC)c(OC)c2)C1 +O=S(=O)(c1cccc(F)c1)N1CCC(Oc2ncccn2)CC1 +Cc1cccc2[nH]cc(CC(=O)NCCOc3cccnc3)c12 +CCc1cc(N2CCC(F)(F)CC2)n2nc(C)c(C)c2n1 +O=C(C1=NC=C(S(=O)(=O)N2CCCCC2)C1)N1CCCC1 +CCN(C(=O)c1ccccc1NC(C)=O)c1ccccc1C +Cc1nc(CNC(=O)NCc2csc(C(C)(C)C)n2)sc1C +CCn1nccc1C(=O)Nc1cc(-c2ccncc2)n[nH]1 +CC(=O)N(Cc1ccco1)Cc1cc2cccc(C)c2[nH]c1=O +COc1ccc(Cl)cc1NC(=O)N1CCCCC1 +Cc1cccc(C(=O)Nc2ccccc2N2CCNC(=O)C2)c1 +CCCCC1CCC(C(=O)N2CC(c3nc(C)no3)C2)CC1 +CNC(=O)C(C)Sc1nnnn1-c1ccccc1C +COCCNC(=O)N1CCN(c2nc3ccc(F)cc3s2)CC1 +Cc1onc(-c2ccccc2)c1C(=O)N(C)Cc1cccc(C#N)c1 +O=C(Nc1nccs1)c1ccc(OC(F)(F)F)cc1 +CC(=O)N1CCC(C(=O)N(CCC(C)C)C2CC2)CC1 +O=C(Cn1ccccc1=O)Nc1ccccc1OC(F)F +Clc1ccc2c(c1)ncn2CCCN1CCOCC1 +Cc1nn(C)c(C)c1CNC(=O)c1cc2sccc2n1C +O=C(Nc1ccccn1)NC1CCN(c2c(F)cccc2F)C1=O +Cc1nc(NCCNC(=O)c2ccccn2)cc(-n2cccc2)n1 +CCn1ccc(C(=O)NCc2ccc(-c3nc(C)cs3)cc2)n1 +CC(C)N1CCOC(CC(=O)NCCc2nc3ccccc3[nH]2)C1 +O=c1[nH]c2ccccc2c(=O)n1CCCNc1ccccc1 +Cc1cc(Cl)ccc1OCC(=O)N1CCOCC1C1CC1 +COc1ccc2cc(C(=O)N3CCCCC3CC(N)=O)[nH]c2c1 +CC1CCCC1NC(=O)NCc1ccc(Cl)cc1 +CCN(CC(C)C#N)C(=O)CN1CCN(C(C)=O)CC1 +Cc1noc(CSc2ccccc2C(=O)OC(C)C(N)=O)n1 +COc1ccc2c(cnn2CCC(=O)N2CCCCCC2)c1 +C=CCc1cccc2cc(C(=O)NCc3cnn(C)c3)c(=O)oc12 +Nc1cnc2nc(CCCOc3ccccc3)[nH]c2c1 +CC(C)=CCN1CCc2ccc(S(N)(=O)=O)cc21 +O=c1[nH]c2cccc(F)c2n1CCN1CCOCC1 +CC(C)(C)C(NC(=O)c1cc(-c2ccccc2)on1)C(N)=O +CC1(C)COC(=O)C1OC(=O)c1ccn(-c2ccccc2Cl)n1 +CCOc1ccc(F)c(C(=O)Nc2cc(C)n(C)n2)c1F +O=C(NC1CCCc2nc(-c3cccnc3)ncc21)C1CCC1 +CC(=O)N1CC(C(=O)NC(c2ccccc2)c2ccccc2)C1 +CC(C)CC(NC(N)=O)C(=O)NC(C)c1cccc(N2CCCC2)c1 +CC(C)Oc1ncccc1CNC(=O)c1cc(-c2ccco2)[nH]n1 +COC(=O)C1CC1C(=O)NCc1ccnc(OC(C)(C)C)c1 +Cc1ccc(NC(=O)COc2cc(C(=O)N(C)C)ccc2C)cc1C +Cc1nn(C)cc1CN(CCC#N)Cc1ccccn1 +CC(Sc1nnc(-c2ccccc2)n1C)C(N)=O +CCCC(C)(C)NC(=O)CNS(=O)(=O)c1cn(C)cn1 +CN(Cc1ncnn1C)C(=O)c1c(-n2cccc2)sc2c1CCC2 +Cn1cc(C(=O)OCCC(F)(F)F)c(C(C)(C)C)n1 +CCc1ccc(OC)c(S(=O)(=O)Nc2ccc(CC(N)=O)cc2)c1 +O=C(CNC(=O)Nc1ccn(-c2ccccc2)n1)NC1CCCCC1 +CC(C)n1ccc(-c2nnc(NC(=O)c3ccccc3)o2)n1 +CC(C)Oc1ccc(CNC(=O)c2cccnc2N)cc1 +COc1ccc(C(C)C)cc1S(=O)(=O)NC1CC1 +Cc1nc2n(n1)CCCC2NC(=O)NC1COc2c1ccc(C)c2C +COC(C)c1noc(CCC(=O)OC2CC3CC(C2C)C3(C)C)n1 +O=C(Cc1ccc(O)cc1Cl)N1CCCCC1c1ncon1 +CC12CN(C(=O)c3ccccc3)C3(C#N)CC1CCC23C +Cc1ccc(Cl)cc1OC(=O)C1CCCN(C(N)=O)C1 +Cc1cccc(N(CCC#N)C(=O)c2cccc(C)n2)c1 +CCN(C)C(=O)COc1ccc(Cl)cc1CO +Cc1ccc(CC(=O)Nc2ncnc3c2CCC3)c(C)c1 +Cc1ccc(C(C)Nc2ncc(N)cc2C#N)s1 +O=C(Cc1csc(-c2ccco2)n1)NC1CCCCNC1=O +O=C(c1cccnc1)N1CCC(c2[nH]ncc2-c2ccncc2)CC1 +COCC(NC(=O)C(C)Cc1ccc(Cl)cc1Cl)C(N)=O +CCC(C)C(=O)N1CCCC1c1ccc2c(c1)OCCO2 +O=C(CCNC(=O)c1ccc(F)cc1F)Nc1ccc(F)cc1F +Cc1cccc(OCC(=O)Nc2ccc(N3CCOCC3)nc2)c1 +CN(C)S(=O)(=O)N1CCCC(C(=O)NC2CC2)C1 +Cc1c(C(=O)N2CCCCC2CNC(N)=O)oc2ccccc12 +COc1ccc(C(O)c2ccc(F)cc2)cc1OC +O=C(CO)N1CCCC(CCc2ccc(F)cc2F)C1 +CCCNC(=O)c1cccc(NC(=O)NC(C)COC)c1 +O=C(CCNC(=O)c1ccsc1)NCCN1CCOCC1 +CCN(C(=O)C1CCOC1)c1cccc(NC(=O)C2CCOC2)c1 +CCNC(=O)Nc1ccccc1CN1CC(C)OC(C)C1 +CCCNC(=O)C1CCCN(C(=O)c2ccoc2)C1 +O=C(Nc1ccc2c(c1)CCC2)C1CCN(c2cnccn2)CC1 +CC(O)CNC1=NS(=O)(=O)c2ccccc2N1 +Cc1cc(F)ccc1NC(=O)c1ccc(N(C)C)nc1 +C=CCN(CC#Cc1ccccc1)Cc1cc(C)n[nH]1 +O=C(Nc1nccs1)c1coc(NC(=O)c2ccco2)n1 +CCN(Cc1cccs1)S(=O)(=O)c1ccc(F)cc1F +CC(=O)N1CCC(C(=O)NC2(CO)CCCC2)CC1 +Nc1cc(S(=O)(=O)NCC2CCC2)ccc1Cl +Cc1cc(CCC(=O)N(C)Cc2ccccn2)ccc1Br +CCc1nnc(SCC(=O)Nc2cccc(OC)c2)o1 +Cc1ccc(CN(C)C(=O)CS(=O)(=O)c2ccc(Cl)cc2)o1 +O=C1NCC(=O)N2CCN(Cc3ccc4c(c3)Cc3ccccc3-4)CC12 +c1cnc(N2CCCC2c2cncc(-n3ccnc3)n2)cn1 +CCCCCC(=O)NCc1cccc(-c2n[nH]c(C)n2)c1 +O=C(CC1CCCC1)OCc1cc(-c2ccco2)on1 +CCOc1cc(N2CCC(N(C)C(=O)OC(C)(C)C)CC2)ncn1 +CCCc1cc(C(=O)N2CC(O)C(N3CCOCC3)C2)[nH]n1 +CC(C)NC(=O)CNC(=O)CNC(=O)c1ccc(Cl)cc1Cl +CCC(Cc1ccccc1)NC(=O)c1cnc(C2CCCO2)s1 +Cc1cc(S(=O)(=O)Nc2ccc(C(=O)NC3CC3)cc2)ccc1F +CC1CCCCC1N(C)S(=O)(=O)c1cc(N)cs1 +CC(=O)Nc1cccc(-c2n[nH]c(-c3ccc(Cl)c(N)c3)n2)c1 +CCCc1n[nH]c(N)c1-c1ccc(OC)c(OC)c1 +Cc1sc2ncnc(NCC3CC(=O)N(C4CCCC4)C3)c2c1C +CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(C)nn2C(C)C)cc1 +CNc1nnc(-c2oc3c(C)cccc3c2COC)s1 +O=C1CN(c2ccc(NC(=O)c3nccc4ccccc34)cn2)CCN1 +COCC(C)NC(=O)NC1(CO)CC(C)CC(C)(C)C1 +CC1CCC(Nc2ccc(CC(=O)N(C)C)cc2)CC1 +C=CCn1c2cc(C)oc2c2cnn(CC(=O)NC3CC3)c(=O)c21 +CCCC1CN(C(=O)c2ccc(N(CC)CCC)nc2)CCO1 +O=C1CCN(C(=O)c2ccc(-n3cnnn3)cc2)CC1 +COc1ccc(-c2c(CO)nnn2-c2ccccc2)cc1OC +CC(=O)Nc1ccc(OCc2nnc(-c3ccc(Cl)cc3)o2)cc1 +N#CCSc1nnc(N2CCc3ccccc3C2)s1 +CCCCn1nccc1NC(=O)C(C)Sc1nncn1C +CC1Sc2ccc(C(=O)NC(C)c3cccs3)cc2NC1=O +Cc1nn(C)c(C)c1CCC(=O)N1CCN(C)CC1 +CC(C)c1nc(C(=O)NCc2noc(-c3ccc(F)cc3)n2)cs1 +CC(=O)c1ccc(OC(=O)CCC2CCCC2)cc1 +COCCCN(C)C(=O)c1cc(-c2ccccc2)nc2onc(C)c12 +CC(C)c1c(C(=O)NCCO)nnn1Cc1ccccc1 +Clc1cc(Cl)c2c(c1)C(c1ncccn1)NCC2 +CC(C(=O)NC1CCN(c2ccccc2)CC1)c1ccsc1 +O=C(CN1C(=O)CCOc2ccccc21)NCC1CC1 +COCCc1nc2nc(C)c(C(=O)OC)cc2c(=O)[nH]1 +CCOC(=O)c1cc(C)sc1NC(=O)CC1CCC(OC)CC1 +Fc1ccc2c(c1Br)C(CC1CC1)NCC2 +Cc1cccc(NCc2ccccc2OCC(=O)N(C)C)c1 +N#CCc1cccc(CN2CCN(c3ncccn3)CC2)c1 +FC(F)(F)c1ccnc(NCc2csc(C3CC3)n2)n1 +CCCN(CC1CC1)C(=O)Nc1cnn(Cc2ccccc2)c1 +CCC(C)NC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1 +CCN1CCOC(CNc2nccc(OC)n2)C1 +CCc1onc(C)c1NC(=O)c1cnc(OC(C)C)c(Cl)c1 +N#Cc1ccc(S(=O)(=O)N2CCCn3ncnc32)cc1 +Cc1ccc(C(=O)N2CCN(c3ccc(O)cc3)CC2)cc1C +CN(C(=O)COc1ccc(Cl)c2cccnc12)C1(C#N)CCC1 +O=C(NC1CC1)C1CCCN(c2cc(-n3cccn3)ncn2)C1 +CCOC(=O)C1CCN(C(=O)c2cn3cccc(C)c3n2)CC1 +Cc1ccc(OC(C)C(=O)NC2CCCCNC2=O)cc1 +O=C(Nc1cccc(OC(F)F)c1)N(CCO)Cc1ccccc1 +CCn1nccc1CNC(=O)Nc1cccc(C(F)(F)F)c1 +Cn1c(=O)c(=O)n(C)c2cc(NC(=O)c3c(F)cccc3F)ccc21 +Cn1cnnc1SCc1nc(Cc2ccccc2)no1 +Nc1c(C(=O)NCc2cc(-c3ccco3)on2)cn2ccccc12 +CCn1ccnc1SCc1nc2c(cnn2C)c(=O)[nH]1 +N#CCCN(Cc1cccs1)C(=O)Nc1ccc2c(c1)CCO2 +COC(=O)c1ccc(C(=O)OCCn2ncc(C#N)c2N)cc1 +C=CCn1c(=O)n(CC=C)c(=O)n(CC(N)=O)c1=O +NS(=O)(=O)c1cc(C(=O)NCCc2ccccn2)ccc1Cl +O=C(NCC1(c2ccccc2)CC1)c1nc2ccccc2c(=O)[nH]1 +Cc1cccc(S(=O)(=O)N(C)CC2(C)CCOCC2)c1 +CCCC(=O)N1CCC(C(=O)Nc2cc(C#N)cn2C(C)(C)C)CC1 +Cc1ccc(NC(=O)N2CC(c3nc(-c4cccnc4)no3)C2)cc1 +COc1ccccc1S(=O)(=O)N1CCCCC1 +NC(=O)c1ccc(NC(=O)COc2cccc(C(F)(F)F)c2)cc1 +Cc1cc(C)c(CNC(=O)c2cccc(C(F)(F)F)c2)c(=O)[nH]1 +CCCS(=O)(=O)N1CC(OCc2csc(C)n2)C2COCC21 +Cc1ccccc1C1(CNC(=O)Nc2ccc(F)c(C(N)=O)c2)CC1 +CN1CC(=O)N(c2ccc3c(c2)CCCN3)CC1=O +CC(C)(Br)C1NCCc2c(F)cccc21 +O=C(Nc1ccc(N2CCOCC2)nc1)c1ccc2[nH]cnc2c1 +CC(c1ccccc1F)N(C)S(=O)(=O)Cc1cccc(C#N)c1 +N#Cc1cc2c(n(-c3ccc(F)cc3)c1=O)CCNC2 +Cc1cccc(NC(=O)N2CCN(C(=O)N3CCOCC3)CC2)c1C +COc1ccc2oc(C(=O)N3CCCN(C(C)=O)CC3)c(C)c2c1 +Cc1n[nH]c(C2CN(Cc3cc(Cl)ccc3OCC#N)CCO2)n1 +COCC(O)CN(C)C(=O)Nc1ccc(OC(F)F)c(F)c1 +COC(=O)c1ccc(COc2cccc(-n3cncn3)c2)cc1F +Cc1cc(C(=O)Nc2ccccc2C(C)C)c2c(C)noc2n1 +COc1cccc(-c2cc(C(=O)N(C)CCc3cnn(C)c3)[nH]n2)c1 +COc1ncccc1CNC(=O)c1ccc(S(C)(=O)=O)cc1 +O=C(CCCc1ccccn1)N1CCCC1Cc1cccc(F)c1 +OC1CCCN(c2cc(-c3ccccc3F)nc3ccnn23)C1 +CCC(=O)c1nc2c(=O)[nH]c(N)nc2nc1SC +CCCOC1CCCN(C(=O)c2ccc(N)nn2)C1 +CC(C(=O)Nc1cccc(Oc2ccccc2)c1)n1cccn1 +Cc1cc(N)nc(SCCC(=O)Nc2ccccc2F)n1 +c1cncc(-c2n[nH]cc2CN2CCCC(c3cn[nH]c3)C2)c1 +CC(C)N(C)C(=O)COc1cc(Cl)ccc1N +Cc1ccc(NC(=O)C2CC2)cc1S(=O)(=O)N1CCCCC1 +COc1ccccc1C(=O)NCc1ccc(C#N)cc1 +N#CCCn1cc(-c2ccnc(N3CCCCC3)n2)c2ccccc21 +COc1ccc(-c2nnc(SC)n(N)c2=O)cc1OC +CSc1nsc(NC(=O)c2ccc(C)s2)n1 +Cc1nc(Cc2nnc(SCC(=O)NCC(C)C)o2)cs1 +Oc1ccc(Cc2nc(-c3cnccn3)no2)c(Cl)c1 +CCC(C)Sc1nnc(C)n1CCc1cccs1 +COc1ccc(F)cc1NC(=O)c1cccc(OCC(F)F)n1 +Cc1ccccc1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +CCOC(=O)c1cc(C)nn1C1CCN(C(=O)CC)CC1 +CC1(NCc2ccc(-n3ccnc3)cc2)Cc2ccccc2C1 +CCOc1ccc(-c2nnc(SCC#N)o2)cc1 +CCN(Cc1cccc(NC(=O)NCc2ccccc2F)c1)C(C)=O +CN(C)C(=O)CNS(=O)(=O)c1ccc(F)c(Cl)c1 +CCC(CO)NC(=O)NCc1cc(Br)ccc1F +O=C(C1CCCN1C(=O)c1cc2ccoc2s1)N1CCOCC1 +CN(Cc1nnc2n1CCC2)C(=O)c1cc(C2CC2)on1 +CC(C(=O)NCCOc1cccc(Cl)c1)n1ccnc1 +CCOC(=O)Cn1c(CC)nc2ccccc2c1=O +O=C(Cc1cccn1-c1ccc(F)cc1)NCc1ccc(F)cc1 +CCC1CNc2cc(S(=O)(=O)N(CC)CC)ccc2O1 +COC(=O)c1cccc2nc(Cc3ccc(OC)cc3)nn12 +Nc1nc(COc2ccccc2Br)nc2sccc12 +CC(c1ccccc1)N(C)C(=O)Cn1nnc2ccccc21 +CC(C)c1cc(C2CCCN2C(=O)CCC(=O)NC2CCCC2)no1 +C=CCCOC(C)C(=O)Nc1cccnc1N(C)C +CCC(NC(=O)N(C)Cc1ccncc1)c1ccc(OC)cc1 +CCN(CC)C(=O)CN(C)C(=O)c1c[nH]c2cccc(F)c12 +Cc1nn(C)c2ncc(S(=O)(=O)N3CC(C)c4ccccc43)cc12 +CC(C)COCCCC(=O)Nc1cccc(C#N)c1 +CCCNC(=O)c1nnc2c(Br)cccc2c1N +CC(=O)Nc1cc(C(=O)Nc2ccccc2Cl)ccc1F +NC(=O)CCN(C(=O)C1CC2CCC1C2)c1ccccc1 +Cc1ccc(CS(=O)(=O)c2ccc(N)cc2)cc1 +c1ccc(Oc2cccc(NCc3cnc4cnccn34)c2)nc1 +O=C(CCn1cc(Cl)cn1)Nc1ccc(Br)cn1 +C=CCn1c(C)nnc1SCC(=O)N1CCCC(NC(C)=O)C1 +Cc1ccc(C(C)Nc2nnnn2-c2ccccc2)o1 +CC(C)CN(C)C(=O)c1cc(N)cc(S(C)(=O)=O)c1 +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1ccn(CCO)n1 +NC(=O)CN(CCC1CCCCC1)Cc1cc(=O)n2nccc2[nH]1 +NC(=O)C1CCCN(C(=O)c2cccc(-c3ccoc3)c2)C1 +Cc1oncc1C(=O)N1CCCC1c1ccsc1 +COc1ccc(C(C#N)NC(=O)c2ccc(F)cc2)c(OC)c1 +Cn1nnnc1SCc1nn(-c2ccc(F)cc2)c2c1CCC2 +COc1ccc2c(CC(=O)Nc3cccc(-n4cnnn4)c3)coc2c1 +C#CCN1CCN(C(=O)NC(C)c2cc(C)c(F)c(C)c2)CC1 +Cc1nc2c(NCCn3cc(Cl)cn3)nc(N)nc2n1C +Cn1ccnc1C(NC(=O)Cc1ccccc1F)c1cccc(F)c1 +Cc1oc(C)c(C(=O)N2CCCN(Cc3nccn3C)CC2)c1C +O=C(NCc1nnc2n1CCC2)Nc1cccc(OC(F)F)c1 +Cc1ccccc1C1CN(Cc2cc[nH]n2)C(C)CO1 +CC(=O)c1cc2c(cc1NC(=O)CN1CC(C)OC(C)C1)OCO2 +CCOC(=O)OCn1c(=O)sc2ccccc21 +O=C(NCCC(=O)N1CCCC1c1ccsc1)c1cccs1 +CC(C)S(=O)(=O)NCCNC(=O)c1ccccc1 +Cn1ncc(Cl)c1C(=O)NC(C)(C)CC(C)(C)C +CC(=O)Nc1cccc(NCc2cc(F)ccc2Br)c1 +COC(=O)c1cccc(OC(=O)Cc2cccc(F)c2)c1 +CC(OC(=O)c1ccco1)C(=O)Nc1ccc(Cl)cc1 +O=C(NCc1cccc(CN2CCCC2=O)c1)c1n[nH]c2ccccc12 +CCN(C=Cc1nnnn1-c1ccc2ccccc2c1)CC +CCCC(=O)N1CCN(c2nc(C)cc(N3CCCCC3)n2)CC1 +COc1ccc2occ(CC(=O)NCc3ccc4c(c3)OCO4)c2c1 +Cc1cc(-c2cc(CO)nn2CCCC#N)ccc1Cl +N#Cc1cccc(NC(=O)c2nc(-c3cnccn3)no2)c1 +Nc1cccc(C(=O)CN2CCCc3ccccc32)c1 +CC(C)CC(=O)N1CCCN(C(=O)c2cnn3c2OCCC3)CC1 +CC(C)(C#N)c1ccccc1Cn1cnc(C2CCC2)cc1=O +O=C(CC12CC3CC(CC(C3)C1)C2)OCCNC(=O)c1ccncc1 +CC(Oc1ccc(N(C)S(C)(=O)=O)cc1)C(=O)N(C)C +COCCn1cc(C(=O)NCc2c(C)cc(C)[nH]c2=O)ccc1=O +CCOC(=O)c1ccc(NC(=O)C2COc3ccccc3O2)cc1 +C=CCNC(=O)CCC(C#N)c1cc(C)ccc1C +Cc1noc(CNC(=O)c2ccc(C(F)(F)F)cc2)n1 +CCN(CC)C(=O)CCC(=O)Nc1cc(Cl)ccc1-n1cccn1 +Cc1cc(N)nc(SCc2cc(=O)n3ccccc3n2)n1 +O=C(Nc1cccnc1)NC(C(F)(F)F)C(F)(F)F +CCc1nc2ccccc2c(=O)n1CC(=O)Nc1cccc(F)c1 +O=C(CNCc1cc2ccccc2[nH]c1=O)NCc1ccco1 +Cc1ccc2cc(CCNC(=O)C(C)(C)C)c(=O)[nH]c2c1 +Cc1cc(C(=O)Nc2ccc(-c3cnc(C)o3)cc2)c2c(C)noc2n1 +O=C(NCCCOCC1CCOCC1)c1cc(=O)[nH]c2ccccc12 +COc1ccc(C(=O)N(C)C)cc1NC(=O)C(C)OC +c1cncc(N2CCOC3CN(Cc4csnn4)CC32)c1 +Cc1ccc(C)c(OC(C)c2nc(N)nc(C)c2C(N)=O)c1 +Cc1ocnc1C(=O)N1CCC(C(=O)N2CCCC2)CC1 +CCOC(=O)c1c(C)nn(-c2cccc(C(F)(F)F)c2)c1C +COc1ccc(C(=O)NC(C)C(c2ccccc2)c2ccccc2)nn1 +CCCc1c(-c2ccco2)nn(-c2ccccn2)c1N +CC(c1cccnc1)N(C)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(C)(C)c1ccc(CSc2nnc(Cn3cncn3)o2)cc1 +COc1ccc(CCC(=O)NC(C)c2ccccn2)cc1 +O=C(c1c2c(-c3ccccc3)ncnc2n2ccccc12)N1CCCC1 +CC(C)(C)NC(=O)c1cc(-c2cccc(F)c2)no1 +Cc1cccc(N2CCN(Cc3n[nH]c(=O)[nH]3)CC2)c1C +CNC(=O)c1cc(C(=O)N(C)C)c(OC2CC2)cn1 +Cc1nccc(N2CCCC(N(C)S(C)(=O)=O)CC2)n1 +COc1cccc(OCC(C)(C)C(N)=O)c1OC +COC(C)C(=O)Nc1cccc(NC(=O)c2cc(C)nn2C)c1 +O=C1CCC(C(=O)Nc2cccc(CSc3ccccn3)c2)CN1 +COc1ccc(CN2CCN(C(=O)c3cccs3)CC2)c(OC)c1 +COCC(C)(O)CNC(=O)c1cc2ccccc2o1 +N#Cc1ccc(COC(=O)c2ccc(CCNC(N)=O)cc2)cc1 +Cc1ccc(F)c(NC(=O)C2CCN(C(=O)c3ccco3)CC2)c1 +CNC(=O)c1cccc(CN2CCCS2(=O)=O)c1 +O=C1CC(c2ccccc2)N(Cc2cnc3ccsc3c2)CCN1 +C#CCNC(=O)C(NC(=O)c1ccc(C)cc1)C(C)C +COC(=O)C(Nc1ccccn1)(OC)C(F)(F)F +CC(CNC(=O)NCCc1ccccn1)CC1(C)OCCO1 +O=C(NCCNc1cnccn1)NCCc1ccsc1 +Cc1nc(CN(C)C(=O)C(C)Sc2nncs2)cs1 +CS(=O)(=O)c1cc2cc(Cl)ccc2oc1=O +Cn1ccc2ccc(C(=O)Nc3ccc4c(c3)ncn4C)cc21 +O=C(NCc1cccnc1)c1cc(-c2ccccc2O)n[nH]1 +CC(Oc1cccc(C#N)c1)C(=O)Nc1ccccc1-n1cnnn1 +Cc1cc(C)nc(N(C)CC2CCCN2C(=O)OC(C)(C)C)n1 +COc1nc(C(=O)Nc2cnc3c(c2)c(C)nn3C)cc2ccccc12 +CCCCNC(=O)C1CCC(C)N(C(=O)Nc2ccc(C#N)cc2)C1 +CCOC(=O)c1sc2nc(SCC)[nH]c(=O)c2c1C +CN(CCOc1cccc(Cl)c1)S(=O)(=O)c1cnn(C)c1 +CC(C)Oc1ccc(C#N)cc1NC(=O)N1CCCCC1C +CC(C)(C)NC(=O)N1CCN(CCc2cccs2)CC1 +COc1cc(Cl)c(NC(=O)c2cc3ccccn3n2)c(OC)c1 +CCCNc1nnc(SC2CCN(c3ccccc3)C2=O)s1 +CC(=O)Nc1ccc(SCC(O)CN2CCOCC2)cc1 +COc1ccc(-c2[nH]c(C)c(C(C)=O)c2N)cc1O +CCCc1cc(C(=O)N2CC3CCC2CN(c2ncccn2)C3)no1 +CNS(=O)(=O)c1ccc2c(c1)NC(=O)C(C)S2 +CCS(=O)(=O)NCCC(c1ccccc1)c1ccccc1 +O=C(CC1C=CCC1)Nc1cccc(CN2CCOC2=O)c1 +CC(C)c1noc(CCCC(=O)N2CCc3sccc3C2C)n1 +O=S(=O)(NCCc1ccccc1F)c1ccc(F)c(F)c1F +Cc1cc(NCCCc2nc3ccccc3n2C)n2nccc2n1 +Cc1nc(C(C)(C)NC(=O)Cc2c(C)noc2C)sc1C +Cn1nc2n(c1=O)CCN(S(=O)(=O)Cc1cccc(F)c1)C2 +Cn1c(C(=O)NC2CCCCC2)cc(=O)n(C)c1=O +CC(=O)Nc1cccc(NCC(=O)c2ccc(F)c(F)c2)c1 +COc1ccccc1C(=O)NCCn1c(C)nc2ncccc2c1=O +O=C1CCC(c2ccc(Br)cc2)CN1 +Cc1c(C(=O)N2CCN(C(=O)C(C)(C)C)CC2)cnn1C +CC(C)(C)n1cc(Nc2ccc(C(F)(F)F)cn2)cn1 +Cc1cc(=O)c2c(C)nn(-c3cccc(Cl)c3)c2[nH]1 +O=C(NCC(F)(F)F)c1cccc(Br)c1 +CCn1cc(CN2CCN(c3ccc(F)cc3OC)CC2)cn1 +CC(NC(=O)CCc1nc2ccccc2s1)C1CCCO1 +COc1cc(Br)cc(C#N)c1OC(C)=O +O=C(CCc1ccco1)N1CCC(Nc2cccnn2)CC1 +O=C(CCOc1ccc(F)cc1)NC1CCCCNC1=O +CCCC(=O)N1CCCN(C(=O)Nc2ccc(C)s2)CC1 +CCCCNC(=O)c1ccc(Cn2ccnc2)cc1 +CCN1CCN(C(=O)c2c(C3CC3)nn(-c3ccccc3)c2C)CC1 +COCCN1CCN(c2ncnc3c2cnn3CCC#N)CC1 +CCCC1CCCN(C(=O)Cc2c(C)nc3nc(N)nn3c2C)CC1 +CC(NC(=O)C1CCCN1C(=O)Cc1cccs1)C1CCCO1 +CC1Cc2c(NC(=O)c3ccc4ccccc4n3)nn(C)c2NC1=O +COc1ccc(C)cc1-n1c(C)nc2ccccc2c1=O +Cc1cccc(CN(C(=O)C2(C#N)CCCC2)C2CC2)c1 +Cc1cnn(CCC(=O)N(C)Cc2nc3ccccc3n2C)c1 +CC(C)c1nccn1-c1cncc(C2CCCN2Cc2ccccc2)n1 +O=C(c1ccccc1)n1ccc(-c2cccs2)n1 +Cc1nc(-c2ccsc2)sc1C(=O)Nc1cccc(C(N)=O)c1 +CC(C)C1CN(c2ccnc(N)n2)CCC(=O)N1CC1CC1 +CC1CCN(C(=O)c2cnc(N(C)C)nc2N)CC1 +Cc1ccc(N(C(C)C(=O)Nc2cccnc2)S(C)(=O)=O)cc1C +Cc1cc(C)n(-c2ccc(NC(=O)C3CCC(=O)N3)cn2)n1 +COc1ccc(C(=O)COC(=O)c2ccc(N)cc2)cc1 +CCOc1ccccc1NC(=O)Cc1ccc(C)nc1 +CN(C)C(=O)CNC(=O)CCc1ccccc1Br +Cc1occc1C(=O)OCCn1c(=O)oc2ccccc21 +COc1ccc(C)cc1NC(=O)CCC(=O)c1ccccc1 +Cc1cnc(C(=O)N2CCc3ccccc3C2)c2cccc(N)c12 +CC(=O)N1CCN(Cc2c(C(C)C)nc3ccc(N)cn23)CC1 +CCn1nc(C)c(CN(C)C(=O)c2nn3cccnc3c2Cl)c1C +O=C(NCc1ccc(-n2ccnc2)cc1)c1ccc(=O)[nH]c1 +Cc1ccc(N2CCc3c(c(COC(C)C)nn3CC3CC3)C2)nn1 +Cc1ccccc1NC(=O)C(C)n1ncc2ccccc2c1=O +CC(=O)c1cccc(NC(=O)Cc2nc3nc(C)cc(C)n3n2)c1 +CSc1cc2c(cc1NC(=O)c1ccncc1F)OCCO2 +NC(=O)c1sc2nncc(-c3ccc(F)cc3)c2c1N +Cc1c(C(=O)C(C#N)c2nc(N)nc(N)n2)oc2c(C)cccc12 +Cc1cccc(C(=O)NCCCN(C)S(C)(=O)=O)n1 +O=C(COc1ccc2c(c1)CCCC2=O)NC1CCCC1 +O=C(NCCc1csc(-c2ccccc2)n1)NCc1ccccn1 +COc1cc(C)sc1C(=O)OCCn1nc(C)cc1C +C=CCN(CC=C)C(=O)c1coc(-c2ccccc2)n1 +O=C1CCN(C(=O)Cc2noc3ccccc23)CC1 +COc1cccc(NC(=O)N2CCC(Oc3cccnn3)CC2)c1 +Cc1ccnc(CC(C)N(C)Cc2cc(C#CCO)cs2)c1 +O=C(NCCCN1CCCC1=O)c1cc(Cl)ccc1-n1cnnn1 +CCCCNC(=O)c1nc(-c2nc(-c3ccncc3)no2)cs1 +COC(=O)c1sccc1S(=O)(=O)NCc1ccncc1 +Cc1nc(C2CCN(C(=O)C(C)OC3CCCCCC3)CC2)no1 +Cc1noc(C)c1S(=O)(=O)NCCC(=O)Nc1ccccc1 +CC(=O)NC1CCCN(C(=O)Nc2cc(C)ccc2F)C1 +O=C(Cc1csc(-c2ccccn2)n1)NCCCN1CCOCC1 +CCCCC(=O)N1CCCN(C(=O)c2cccc(Cl)c2)CC1 +CC1(C)Nc2ccccc2N(Cc2ccc(C#N)cc2)C1=O +Fc1cc(CNc2ncnc3[nH]cnc23)ccc1Oc1cccnc1 +Cc1nc(-c2ccc(NS(=O)(=O)c3cn(C)nc3C)cc2)cs1 +COc1ccc(S(=O)(=O)Nc2ccc(C)c(O)c2C)cc1 +Cn1ncc2cnn(CC(O)c3cccc(Cl)c3)c2c1=O +COc1ccc(C(=O)NC2CCC(O)CC2)cc1-c1ccccc1 +CC1CN(S(=O)(=O)c2cccc(C(=O)N3CCC3)c2)CC(C)O1 +CC(C)c1cc(CNC(=O)NC(c2nnc3n2CCC3)C(C)C)on1 +C=CCNC(=O)Nc1ccc(Br)cc1 +CCOc1ccc(NC(=O)CNc2ccc(C#N)cc2)cc1 +O=C(Cn1ncc2ccccc21)NCc1cn(-c2ccccc2)nn1 +Nc1nc(-c2ccncc2)ncc1C(=O)Nc1ccccc1F +COCCOCCCC(=O)N1CCN(C(C)=O)CC1 +Cc1ccc2c(CSc3nnnn3C(C)(C)C)cc(=O)oc2c1 +C=CCCC(=O)N1CCC2(CCCN(Cc3cccc(C)c3)C2=O)C1 +CC(=O)Nc1ccc(-c2c(C)cc(C)cc2C)cn1 +CCn1ncc2c(C(=O)Nc3cc(C)no3)cc(-c3ccccc3)nc21 +O=C(Cn1cnc2ccccc2c1=O)NC1CCc2c(O)cccc21 +CCCc1cc(=O)[nH]c(SC(C)C(=O)N2CCCC2)n1 +Cc1cnc(NC(=O)C(C)Oc2ccc(C#N)cc2)s1 +CC(=O)N(C)Cc1cccc(NCc2ccc(F)c(F)c2)c1 +CCC1C(=O)NCCN1Cc1c(C)nn(-c2ccc(F)cc2)c1C +Cc1noc(C)c1CC(=O)Nc1cccc(-c2nnnn2C2CC2)c1 +Cc1cc(C(=O)N2CC(C(=O)Nc3ccc4c(c3)OCO4)C2)no1 +Cc1cc(=O)nc2sc(N3CCN(C(=O)NC4CC4)CC3)nn12 +CCOc1ccc(OCC(=O)Nc2ccccc2-n2ccnc2)cc1 +COc1ccc(CNC(=O)NC2CCc3cc(F)ccc32)cc1OC +Cc1ccc(NCC(=O)N2CC(C)CC(C)C2)cc1-n1cnnn1 +Cc1noc(C2CC(=O)N(c3ccc(C(C)C)cc3)C2)n1 +COc1ccc(CCCC(=O)NCc2cc(C)oc2C)cc1 +Cc1cccc(OC(C)C(=O)NCc2ccco2)c1C +CCOc1ccc(-c2ccc(C#N)c(=O)n2CC#N)cc1 +Cc1cc(C)c(S(=O)(=O)Nc2cccc(C)c2C(N)=O)c(C)c1 +CCCOC(=O)c1ccc(NCC(=O)N2CCC(C)CC2)cc1 +Cc1cc(F)ccc1NC(=O)NCCCN1CCOCC1 +COc1cc2nc(-c3cccc(-c4ccn[nH]4)c3)nc(N)c2cc1OC +COC(=O)CCNC(=O)c1cc(Br)c[nH]1 +CN(Cc1cccc(-c2cccnc2)c1)CC(O)CN1CCOCC1 +COCCN(Cc1cnn(C)c1)C(=O)c1nccc2ccccc12 +Cc1nc(C)c(C(=O)N2CCCc3cccc(OC(F)F)c32)s1 +CC(C)CCNC(=O)N1CCN(CC(=O)NC(C)C)CC1 +Cc1cc(C)c(CNC(=O)c2cn3ccccc3n2)c(C)c1 +Cc1ccc2c(c1F)C(c1cccnc1C)NCC2 +O=C(Nc1cccc(OCC2CCCO2)c1)NC1CCC(O)CC1 +CC(C)OC(=O)c1cc(-c2ccco2)n(-c2ncccc2Cl)n1 +Cc1cc(-c2ncc3c(Br)ccn3n2)on1 +C#Cc1cccc(NC(=O)NCCNC(=O)c2cccnc2)c1 +COc1ccc(C(=O)NCc2cccc(-c3nc(C)n[nH]3)c2)nn1 +N#Cc1ccccc1Cn1cnc2cc(Cl)ccc2c1=O +O=C(Nc1ccccc1)C1CCCN1C(=O)c1cc2sccn2c1 +N#Cc1ccc(OCCCNc2ccccc2-n2cccn2)cc1 +COC(=O)c1sc2nc(-c3ccco3)cc(C(F)(F)F)c2c1N +CC1CCCN(C(=O)C2CC(=O)N(C)C2c2ccc(F)cc2)C1 +COc1cc(OC)c2[nH]c(C(=O)NCC(F)(F)F)cc2c1 +CC(=O)Nc1cc(NC(=O)c2n[nH]c3ccccc23)ccc1C +CCn1cc(-c2nn3c(-c4ccccn4)nnc3s2)c(C)n1 +CC(C)(C)OC(=O)CSc1nnnn1-c1ccc(Cl)cc1 +COCC(O)CN(C)C(=O)c1ccc(C(N)=O)cc1 +Cn1cc(C(=O)Nc2ccccc2OC2CCCC2)ccc1=O +O=C(COC(=O)c1ccc[nH]c1=O)NC1CCCCC1 +CC1CN(C(=O)c2cccc(-c3ccoc3)c2)CC(c2ccccc2)O1 +Cc1cc(NCCNC(=O)c2ccc(F)cc2F)n2ncnc2n1 +COc1ccc2oc(-c3cc(O)cc(O)c3)cc(=O)c2c1 +COc1cccc2c1OCC(=O)N(c1ccc3c(c1)OCCO3)C2 +c1ccc2oc(CNc3ncnc4ccsc34)cc2c1 +Cc1ccc(C(=O)Nc2ccc(N3CCOCC3)c3nonc23)cc1 +COc1ccc(C(O)CNS(C)(=O)=O)c(OC)c1 +Cc1cnc(NC(=O)C2CCC(=O)N(C)C2c2ccccc2F)s1 +C#CCOC(=O)c1cccc(Nc2nc(C)ccc2N)c1 +Cc1ccc(OCCn2c(CO)nc3ccccc32)cc1 +Cc1nc(CC(=O)NCCc2csc3c2CCCC3)cs1 +COC(=O)c1cnc(-c2ccc3c(c2)OCO3)s1 +CCC(C)C(C)NC(=O)COc1ccccc1N +COc1ccc(C(=O)CCC(=O)Nc2nc(C)c(C)s2)cc1OC +COC(CNS(=O)(=O)c1ccccc1)n1nnc2ccccc21 +O=C(NCCCNc1ncccn1)c1cnns1 +CCOC(=O)CCC1NCCc2cc(OC)c(Cl)cc21 +CCN(Cc1cccc(C)c1)C(=O)Nc1ccc(F)c(C(=O)NC)c1 +COc1ccc(F)cc1NC(=O)C(C)Oc1ccccc1C#N +Cc1noc(Cc2ccccc2NS(=O)(=O)c2ccccc2)n1 +O=C(NCCc1cccnc1)c1ccc(COc2ccc(F)cc2)o1 +COC(=O)c1sccc1NC(=O)c1ccccc1C(F)(F)F +Cc1ccc(CNC(=O)CN2CCN(C(=O)CO)CC2)cc1F +Nc1cnc(Cc2ccc3c(c2)NC(=O)CO3)nc1 +Cc1nnc(-c2cccn2CC(=O)Nc2ccc(Cl)cc2F)o1 +Fc1cc(F)c(F)c(CNCc2cnc(C3CCC3)s2)c1F +Cc1nc(-n2cccc2)sc1C(=O)NCCN1CCOCC1 +CN(Cc1ccc(F)cc1)C(=O)c1ccccc1-n1cnnn1 +CCN(CC)C(=O)CCNC(=O)NC(C)c1c(C)nn(C)c1C +O=C(Nc1nc(-c2ccco2)cs1)c1cnns1 +COc1ccccc1NC(=O)C(C)NCc1ccc(F)cc1 +CCOC(=O)CCn1nncc1-c1cccc(N)c1 +CNC(=O)CSc1nnc(-c2cccc(C)c2)n1C +Cc1cc2nc(-c3cccnc3)cc(C(F)(F)F)n2n1 +COc1ccc(S(=O)(=O)Cc2ccc(C(F)(F)F)cc2)cc1 +CCOCCC(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +COc1cccc(CCNC(C#N)c2ccc(F)cc2)c1 +CC(=O)c1cc(Cl)ccc1OCC(=O)N(C)Cc1ccco1 +Cc1nc(C2CCN(C(=O)NCC(C)(C)c3ccncc3)CC2)no1 +CN(C)S(=O)(=O)Nc1ccc(Br)cc1 +Nc1ccccc1C(=O)NCc1ccc2c(c1)OCO2 +CC(C)n1ncc2cc(C(=O)Nc3cccc4cccnc34)cnc21 +CCc1noc(CC)c1CNC(=O)NC(C)C1CCCO1 +CC(=O)N(CCCNC(=O)c1ccc(F)cc1)C(C)C +COc1ccc(CNS(=O)(=O)c2cc(F)ccc2F)cc1 +CCOc1ccc2c(c1)CC(C(=O)N1CCCCC1CCO)CO2 +COc1ccc(C(C)NC(=O)NCc2ccncc2)cc1F +O=C(NCc1ccncc1)c1ccccc1OCc1ccccc1 +CCCNC(=O)CN(C)C(=O)CN1CCC(C)c2ccccc21 +Cc1cc(-c2nn3c(-c4cccc(Cl)c4)nnc3s2)[nH]n1 +CCCc1n[nH]c(NC(=O)NCCc2cccc(OC)c2)n1 +CCOc1ccccc1C(=O)NCCCC(=O)N1CC(C)OC(C)C1 +CCC(C)C(C)(O)CNC(=O)NCC1CN2CCCCC2CO1 +Cc1nc(SCC(=O)N(C)CC2CCCCC2)oc1C +CC(C)C(Oc1ccccc1C#N)C(=O)Nc1ccc2c(c1)COC2 +CCOc1ccc(CN(C)C(=O)c2cc3c(C)nn(C)c3s2)cc1 +Cc1ccc(N2CCCS2(=O)=O)cc1NC(=O)C(C)(C)C +Cc1n[nH]c(-c2ccc(C(=O)N(Cc3cccnc3)C3CC3)cc2)n1 +CC1CC(C)CN(C(=O)CNC(=O)c2ccn(C)n2)C1 +Cc1ncc(CNC(=O)N2CC(C)CC(C)C2)s1 +CC(C)Sc1ccc(C(=O)NCC(=O)NC(C)(C)C)cc1 +COc1cccc(C(=O)n2cc(C#N)c3ccccc32)c1 +O=c1[nH]nc(-c2nc(-c3c[nH]c4ccccc34)no2)c2ccccc12 +Cc1ccccc1NC(=O)c1ccc(-c2ccsc2)nc1 +Cn1c(C(=O)N2CCOCC2)nc2c1CCN(S(C)(=O)=O)C2 +CC(C)Oc1ccccc1NC(=O)c1cnn(C)c1N +COc1ccc(CNC(=O)c2c[nH]c3cccc(F)c23)cc1OC +Cc1cccc(NC(=O)CCCNC(=O)c2ccccc2)c1C +CN(C)c1ncnc(NCCN2CCOCC2)c1N +CCN1CCN(C(=O)c2cnc3nc(C(F)(F)F)nn3c2C)CC1 +CC(C)N(C(=O)CCc1nc(-c2cccs2)no1)C1CCC1 +CC(C)C(NC(=O)c1ccc2c(n1)NC(=O)CC2)C(=O)NC1CC1 +Nc1nnnn1CC(=O)N1CCCC(CNC(=O)c2cccs2)C1 +CC(C)(NC(=O)Cc1ccc[nH]1)c1ccc2c(c1)OCCO2 +O=C(C1CCC1)N1CCc2c(c(CO)nn2Cc2ccccc2)C1 +CCC(C)C(=O)Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1 +O=C(Cn1nc(-c2ccccc2)ccc1=O)N1CCc2ccccc2C1 +Cc1ccc(C(C)NC(=O)c2csc(S(N)(=O)=O)c2)cc1F +O=c1cc(CN(CCO)c2ccccc2)c2cc3c(cc2o1)CCC3 +Cc1oc(C)c(C(=O)N2CCN(Cc3ccccn3)CC2)c1C +Cc1cc(C)n2nc(SC(C)C(=O)N3CCC(C)CC3)nc2n1 +CC(C)N(CC(F)(F)F)C(=O)c1cc(F)c(F)c(F)c1 +Cc1cccc(C(=O)Nc2cc(C)nn2-c2ccccc2)c1 +O=C1CCCc2c1cnc1nc(-c3ccccc3)nn21 +CCOCCNC(=O)Nc1ccc(C(=O)N(C)C)c(C)c1 +COc1cccc(CC(NC(C)=O)C(=O)NCc2ccccc2)c1 +COc1ccc(NS(=O)(=O)c2ccccc2C#N)cc1 +Cc1c(NS(=O)(=O)c2ccccc2)cccc1C(=O)N(C)C +Cc1sc(NC(=O)c2onc(C#N)c2N)c(C#N)c1C +CC1CCCCN1C(=O)NCc1ccc(N2CCCCC2=O)cc1 +Cc1c(C(=O)N(CCC#N)Cc2ccco2)oc2c(Cl)cccc12 +Cc1occc1-c1nnc(SCC(=O)NC2CC2)n1C +Cc1nn(C)c(C)c1C(=O)Nc1cc(Br)c(=O)n(C)c1 +COCC(O)CN(C)C(=O)c1cc(C)ccc1O +C#Cc1cccc(NC(=O)Cc2ccc(-c3csc(C)n3)cc2)c1 +COc1ccc(C(=O)NCC(=O)NCc2ccc(C#N)cc2)cc1 +CCN(CC)S(=O)(=O)Nc1cc(OC)ccc1N +Cn1cc(CCC(=O)Nc2ccc(Oc3cccnc3)nc2)cn1 +NC(=O)Nc1cccc(C(=O)N2CCC(n3cccc3)CC2)c1 +CS(=O)(=O)NCCNC(=O)CCc1cc(F)ccc1F +COc1ccc(CC(=O)Nc2nc(C)cs2)c(OC)c1 +Cc1ccc(CN(C(=O)CSc2nnc(C)s2)C2CC2)o1 +CCc1nnnn1CC(=O)N1CCN(c2ccccc2OC)CC1 +CCN(C)c1ncnc2c1CCN(C(=O)c1cccn1C)CC2 +COC(=O)C1CCN(C(=O)c2cc3n(n2)CCCO3)CC1 +O=C(Cc1nc(-c2ccccn2)n[nH]1)NCc1cc(F)cc(F)c1 +Cc1nc(C(=O)N2CCC2)nn1-c1ccc(F)cc1 +Cc1ccc(C2COCCN2Cc2ncccc2C(F)(F)F)o1 +CC(C)OCc1cccc(NC(=O)CNC(N)=O)c1 +Cc1ccc(C(=O)N2CCOCC2)cc1NC(=O)c1sccc1C +O=C(NCCc1ccc2c(c1)OCCO2)NCc1ccccn1 +COc1ccc(OC(C)C(=O)Nc2ccc(N)cc2OC)cc1 +Cc1nc(NC(=O)c2cc(Cl)ccc2O)sc1C +Cn1c(-c2ccccc2F)nnc1S(=O)(=O)Cc1ccon1 +NC(=O)C1CCN(C(=O)NCCc2ccccn2)CC1 +CCOCC(=O)N1CCCC2(CCC(=O)N(Cc3ccncc3)C2)C1 +CCc1nnc(SCC(=O)c2ccccc2)n1N +CC(C)c1nc(CC(=O)N2CCC(CN3CCOCC3)C2)cs1 +CCc1cc(=O)n(CC(=O)NC2CCCC2)c(-c2ccccc2)n1 +Cc1sc(=O)n(CC(=O)Oc2cccc(S(C)(=O)=O)c2)c1C +CC(C)(C)OC(=O)N1CCCC2(CCCOC2)CC1 +CCn1cnnc1CNC(=O)c1ccc(OCC2CC2)cc1 +Cc1occc1CN(C)C(=O)CN1CCCS1(=O)=O +CCCc1nnc(NC(=O)Cn2ccc3ccc(Cl)cc32)s1 +O=C(CSc1nnnn1-c1ccccc1)Nc1cccc(Cl)c1 +COCC(=O)N1CCC2(CC1)COC(COCc1cccnc1)C2 +O=C(NCc1cnn(Cc2ccccc2)c1)Nc1cc(F)cc(F)c1 +Cc1cc(C(=O)OCCc2c(C)n[nH]c2C)cc(=O)[nH]1 +CNC(=O)Cn1ccsc1=NC(=O)c1ccc(OC)c(OC)c1 +Cc1cccc(CNC(=O)CC2Sc3ncccc3N(C)C2=O)c1 +COC(=O)c1ccc(C(=O)Nc2ccc3c(c2)COC3)cn1 +CCNc1ncnc(Nc2nc3ccc(C)cc3s2)c1N +N#CCCN(C(=O)c1cccc(F)c1)c1ccccc1 +CCOC(=O)c1nocc1C(=O)c1ccc(F)cc1 +Cc1ccc(C)c(NCC(=O)Nc2ccccc2N2CCCC2=O)c1 +CCC(NCC(=O)OC)c1ccc(Cl)cc1Cl +CCc1oc2c(c1-c1nnc(NCCOC)s1)CCC2 +CCOCC(=O)NCCc1ccc(S(N)(=O)=O)cc1 +Clc1cnccc1CNc1ccccc1Cl +CC(C(=O)NC1CC1)N(C)Cc1nc2ccccc2c(=O)[nH]1 +Cc1noc(C)c1S(=O)(=O)Nc1ccccc1 +Cc1ccc(CCNS(=O)(=O)c2cnn(C(C)C)c2)cc1 +O=S(=O)(NCc1cc2ccccn2n1)c1ccccc1F +COC(C)(C)c1noc(-c2cnc(-c3ccccc3)nc2)n1 +Cc1cccnc1NC(=O)CCC(=O)c1ccc(Br)cc1 +N#CCCN(CCC(F)(F)F)CC1=Cc2ccccc2OC1 +CN(C)C(=O)CN1CCN(S(=O)(=O)c2ccccc2)CC1 +COCc1nnc(NC(=O)c2nc(C)sc2C(C)C)s1 +CCOc1ncccc1CN(C)C(=O)NC(C)(C)C +CC(NS(=O)(=O)c1ccc2c(c1)oc(=O)n2C)c1ccccn1 +O=C(CCC(=O)c1ccc2c(c1)OCCO2)Nc1cccnc1 +CCC(C)(C)NC(=O)C(C)Nc1ccc(NC(C)=O)c(OC)c1 +COCCCC(=O)N1CCCN(C(=O)c2ccncc2)CC1 +CCNc1cncc(S(=O)(=O)N2CCC(C)CC2)c1 +Cc1ccc(C(O)C2NCCc3ccc(F)c(F)c32)cc1 +O=C(NCC(O)c1ccco1)c1n[nH]c(=O)c2ccccc12 +COC(=O)c1sc(NC(=O)c2ccc(OC)c(OC)c2)nc1C +CC(NC(=O)NC(c1ccc(F)cc1)C1CCCC1)c1nncn1C +COc1ncccc1C(=O)NC1CCN(c2c(F)cccc2F)C1=O +Cc1cnc(C(=O)NCc2ccccc2-n2ccnc2)cn1 +CCOC(=O)C(C)(C)n1c(N)nc2cc(F)c(F)cc21 +CC1CC(=O)Nc2ccccc2N1C(=O)COC(=O)c1cnccn1 +CCCC(=O)NCC(=O)Nc1ccc(N2CCCCC2)cc1C(N)=O +COc1ccc(OC)c(NC(=O)Nc2c(C)nc3ncnn3c2O)c1 +Cc1[nH]c2ccc(N(C)C)cc2c(=O)c1CCC#N +CCc1ccc(C2COCCN2Cc2ccccc2NC(C)=O)o1 +CN(Cc1nnc(-c2cc3c(s2)CCCC3)o1)Cc1nccs1 +COc1ccccc1OCC1NCCc2ccc(C)cc21 +O=C(NCc1coc(-c2cccs2)n1)c1cc2ccccc2[nH]1 +N#Cc1ccc(CS(=O)(=O)NC2CCCCCC2)cc1 +COc1c(F)cc(NC(=O)Cn2cnc3ccccc3c2=O)cc1F +CC(C)C(NC(=O)Nc1ccnc(C(=O)N(C)C)c1)c1ccccc1 +O=C(NCCc1cc(F)ccc1F)N1CCC(OCC2CC2)CC1 +CC1OCCN(Cc2ccc(OC(F)F)c(F)c2)C1C +CCC(C)n1nccc1NC(=O)c1ccc2[nH]cnc2c1 +NC(=O)NC(Cc1ccccc1)C(=O)NCCC1CCCCC1 +COc1ccc(C(=O)NCCNC(=O)c2ccc(O)c(Cl)c2)cc1 +O=C(Nc1cccc(-n2cnnn2)c1)C1CC1c1ccccc1Cl +COC(=O)NCC(=O)Nc1ncccc1OCC1CCCCC1 +N#Cc1cnn(-c2ncc(C(F)(F)F)cc2Cl)c1N +CC(C)(C)c1nnc(CN2CCCC(c3ccn[nH]3)C2)o1 +CCOC(=O)CCn1c(=O)c2c(nc3n(C)c(C)cn23)n(C)c1=O +O=C(NCC1CN(C2CC2)CCO1)Nc1cccc2ccccc12 +Cc1nc(CN(C)C(=O)C2COc3ccc(F)cc3C2)cs1 +CCCOc1ccc(C(=O)NC2CCC(O)CC2)cc1OCC +Cc1ccc(C)c(NS(=O)(=O)c2c(C)[nH]c(=O)[nH]c2=O)c1 +CCOC(=O)c1nc2sc(C3CC3)nn2c1CO +Cc1cnc(C(=O)N2CCOCC(CO)C2)cn1 +CCc1cc(CCN2CCCC2=O)nc(N2CCCCC2)n1 +O=C(CCC(=O)Nc1nccs1)NCc1ccccc1F +CCN(CCC#N)C(=O)c1cc(Cl)ccc1Cl +N#Cc1ccc(C(=O)N2CCn3cc(Cn4cccn4)nc3C2)cc1 +Cc1ccc(OCCN2CCOc3ccc(N)cc32)cc1 +CC(O)CNC(=O)c1ccc2nc(-n3cccc3)sc2c1 +CC(=O)NCCCC(=O)NC(c1cccs1)C(C)(C)C +O=C(Cc1ccc(Cl)c(Cl)c1)N1CCNCC1 +CC(Cn1ccnc1)NC(=O)c1cccc(N(C)C)c1 +COc1cccc(S(=O)(=O)NCCc2ccsc2)c1 +OC(COCc1ccccc1)Cn1ccnc1-c1cccnc1 +CN(C)C(=O)c1ccc(CNS(=O)(=O)c2ccc(C#N)cc2)cc1 +Cn1c(=O)ccn(CC(=O)N2CCN(C(=O)c3ccco3)CC2)c1=O +CCOC(=O)CN(C)C(=O)C1CC(=O)N(C(C)C)C1 +CC1=C2CC3(C)C(C)CCCC3C(O)C2(O)OC1=O +Cc1cc2c(=O)n(CC(=O)Nc3ccccc3)c3cccnc3n2n1 +CC(C)C(C)NC(=O)c1cc2sc(N(C)C)nc2s1 +O=C(NCCN1CCCCCC1=O)c1cc(C2CC2)[nH]n1 +COc1cccc(NCC(O)COc2cccc(C)c2)c1 +O=C(Cn1cc(Br)c(=O)[nH]c1=O)Nc1cn[nH]c1 +Cc1cc(NS(=O)(=O)N2CCCCC2C)ccc1N +Oc1ccc(-c2ccc(C(O)CN3CCOCC3)cc2)cc1 +COc1cccc(C(=O)NC2CCN(c3cnn(C)c3)C2=O)c1F +CCS(=O)(=O)N1CCC(n2cc(Cc3ccccc3)nn2)CC1 +Fc1cc(Cl)cc2c1CCNC2C1CCCO1 +O=C(Cc1csc(N2CCNC2=O)n1)NC(C1CC1)C1CC1 +CCCN(CC1CC1)C(=O)NCC(=O)N1CCCC1 +COC(=O)Cc1csc(COc2ccc(C)cc2)n1 +COC(=O)CC1(CS(=O)(=O)N(C)c2cccc3ncccc23)CC1 +CN(Cc1ccccc1OC(F)(F)F)C(=O)c1ccc(C#N)cc1 +Cc1nc2ccc(C(=O)OC(C)C(=O)NC3CCCC3)cc2nc1C +Cc1ccc(C(=O)NCCNC(=O)CCn2ccccc2=O)cc1F +CCOc1c(CN(C)C(=O)c2cn3ccsc3n2)cccc1OC +N#CC(C(=O)c1cccc(F)c1)c1ccc(C(F)(F)F)cn1 +CC(C)c1ccc2c(c1)C(c1ccnnc1)NCC2 +CC(Cn1cncn1)C(=O)Nc1cccc(N2CCCC2)c1 +Cc1oc(C(=O)NCCCCC(C)(C)C)cc1S(N)(=O)=O +COc1ccc(-c2nc3ccc(Cl)cn3c2C(C)O)cc1OC +Cc1nn(C)cc1CNC(=O)C(C)Oc1ccc(Cl)cc1Cl +COc1ccc(C(=O)Nc2cc(C#N)ccc2C)c(O)c1 +CCCCOc1ncnc2c1[nH]c1ccc(F)cc12 +CCc1onc(C)c1NC(=O)N1CCOC(c2nccs2)C1 +Cc1cc(C(=O)COC2CCC(C)CC2)c(C)n1C +COc1ccnc(NC(=O)C2CC2c2ccc3c(c2)OCCO3)c1 +Cc1cc(C)n(-c2nc3nonc3nc2-n2nc(C)cc2C)n1 +CNC(=O)c1cc(C)ccc1NCc1nnc(-c2ccccc2C)o1 +Cc1ccc(-c2nnco2)cc1NC(=O)c1cn[nH]n1 +O=C(NCC(O)c1ccc(F)cc1)Nc1ccc(-n2ccnn2)cc1 +Cc1ccc(OCC(=O)NC(c2ccccc2)c2nccn2C)cc1C +N#Cc1ncn(CC(=O)Nc2ccnn2Cc2ccccc2Cl)n1 +N#Cc1cccnc1NCCCc1nc2ccccc2s1 +CC(C)(C)NC(=O)Cn1c(C(O)c2ccccc2)nc2ccccc21 +CC(C)(C)NC(=O)c1ccc(OCC(N)=O)c(N)c1 +C=C1CCN(C(=O)C2CCN(S(=O)(=O)CCCC)CC2)CC1 +Nc1cccc(C(O)CCC(=O)NCc2cccnc2)c1 +COc1cccc(CC(=O)Nc2ccccc2C(C)=O)c1 +CCC(Sc1cc(C)ncn1)C(=O)Nc1cccc(C(C)=O)c1 +COc1cc(N2CCN(Cc3ccc(C)c(C)c3)C(=O)C2)ncn1 +COc1ccc(OC)c2c1cc(C(=O)Nc1nccs1)n2C +COc1ccc(CN2CCN(c3cc(OC)ncn3)CC2=O)cc1 +COc1ccc(F)cc1NC(=O)c1cccc(F)n1 +Cc1nn(C)c(C)c1-c1cc(C(=O)NCc2csc(=O)[nH]2)[nH]n1 +O=C(OCCc1ccc(F)cc1)c1ccc2nncn2c1 +CCOC(=O)CN(C)S(=O)(=O)c1ccc(NC(C)=O)cc1 +CCN(CC)C(=O)CCc1cc2ccccc2[nH]c1=O +CCSc1cc(C(=O)Oc2ccc(-n3cnnn3)cc2)ccn1 +CC(C)(CO)Nc1ccc(NC(=O)c2ccccc2)cn1 +COc1ccc(-c2nnc(NC(=O)CCn3cccn3)s2)cc1 +CC(C)(C)n1nnnc1SCCOc1cccc(C#N)c1 +CCS(=O)(=O)c1ccc(NC(=O)NCc2ccccc2F)cc1 +CC(C)c1cccc(C(C)C)c1NC(=O)c1cscn1 +C#CCNC(=O)c1cc2c(C)nn(-c3ccccc3)c2s1 +Cc1cc(C)n2nc(C(=O)N3CCOc4cc(F)ccc43)nc2n1 +Nc1nc(N)c2nc3c4ccccc4c4ccccc4c3nc2n1 +CC(C(=O)c1c[nH]c2ccccc12)n1nc(-c2cccs2)oc1=O +CC1(C)CN(C(=O)c2ccc(-n3ccnn3)cc2)c2ccccc2O1 +CC(C)S(=O)(=O)NCc1ccccc1-n1cccn1 +O=C(NCc1ncc2c(n1)CCC2)c1cnc(Nc2ccccc2)nc1 +Cc1csc(SCc2nc(N)c3ccccc3n2)n1 +CCc1nnc2n1CCN(Cc1ncc(-c3ccccc3)o1)C2 +CCNC(=O)c1ccc(CNC(=O)c2cnn[nH]2)cc1 +COC(=O)c1ccc(NCCN2CCOCC2)cc1 +CC(C)CNC(=O)c1ccc(Cl)c(S(=O)(=O)NC2CC2)c1 +NC(=O)CSc1ccccc1NC(=O)CCc1ccc(F)cc1 +O=C(NCCO)c1cccc(NC(=O)c2cccs2)c1 +CCS(=O)(=O)NCCN(C)c1ccccc1N +CN(C)C(=O)c1ccc(NC(=O)COc2ccc3ccccc3c2)cc1 +Cc1nc2ccccc2n1CCNC(=O)c1c[nH]c2ccccc12 +CN1CCN(C(=O)CN2C(=O)CCCc3ccccc32)CC1 +COc1cccc(NC(C)C(=O)Nc2cccc(C#N)c2)c1 +COc1cccc(CCNC(=O)NC(C)C)c1O +O=C(Nc1ccn(Cc2ccccn2)n1)c1ccc(OCC2CC2)cc1 +O=C(NCc1cccc(-n2cncn2)c1)Nc1nnc(C2CC2)s1 +Cc1csc(NC(=O)COC(=O)c2ccc(O)cc2)n1 +CCCC1CCC(NC(=O)c2ccc3c(c2)NC(=O)CO3)CC1 +Cc1nn(C)c(C)c1C(C)NC(=O)c1ccccc1F +CN1C(=O)CN(C(=O)c2cccc(-c3ccoc3)c2)c2ccccc21 +O=C(c1ccccc1)N1CCCN(C(=O)c2ccccc2)CC1 +O=S(=O)(c1cccs1)N1CCCC1C1CCCC1 +CCC(NC(=O)Cc1cccc(OCC#N)c1)c1cccs1 +CCOc1ccc(Cl)cc1S(=O)(=O)Nc1ccccc1O +CC(=O)Nc1cccc(C(=O)NCc2c[nH]nc2C)c1 +Cc1ccc2nc(NC(=O)c3cnc4c(c3)c(C)nn4C)sc2c1 +CC(CC#N)N(C)C(=O)Nc1ccc(CNS(C)(=O)=O)cc1 +Cn1c(C(=O)Nc2ccncc2)cc2ccccc21 +CCOC(C)c1nc(CS(=O)(=O)c2ccc(C)cn2)cs1 +CC1NC(=O)C2CN(C(=O)c3ccc(C#N)cc3)CCN2C1=O +O=C1Nc2c(O)cc(Cl)cc2C(C#CC2(O)CC2)(C(F)(F)F)O1 +Cc1ccc(F)c(C(=O)N2CCC3(CC2)CNC(=O)C3)c1Cl +Cc1cc(NC(=O)c2cccc(F)c2)n(C(C)C)n1 +CC(C)CCNC(=O)CC(C#N)c1ccc2c(c1)OCO2 +c1ccc(-n2nnnc2Sc2ncccn2)cc1 +Cc1nccc(C(=O)Nc2ccc(OC(F)(F)F)cc2)n1 +Cc1cc(C)cc(C(=O)NCC(=O)N2CCc3ccccc32)c1 +C=CCNc1ncnc(Nc2ccc(Br)cc2)c1N +CC(C)NC(=O)CC1(C(=O)NCc2ccccc2F)CCCC1 +COC(=O)C(C)N1CCN(Cc2nc(N)c3ccccc3n2)CC1 +CN(CC(=O)NC(C)(C)C)C(=O)c1ccc2c3c(cccc13)CC2 +CC(=O)Nc1cc(NC(=O)NC(C)C(C)CO)ccc1C +O=C(Nc1cc(F)c(F)c(F)c1)OCC(F)(F)F +CCCN1CCNC(Cc2ccc(-c3ccncc3)cc2)C1=O +CCc1ccc(C(=O)Nc2ccccc2SCC(N)=O)cc1 +CC(C)OC(=O)CNC(=O)Nc1cc(F)ccc1OC(C)C +CC(C)(C)c1ccc(NC(=O)c2cccnc2N)cc1 +CC(=O)Nc1ccc(OC(=O)C(C)n2ccnc2)cc1 +Cc1ccc(C#N)c(SCC(=O)Nc2ccc(F)cc2)n1 +CCC(CC)C(=O)NCC(=O)c1ccc2c(c1)OCO2 +COc1cccc(C(=O)N(C)CCCOc2ccc(F)cc2)c1F +Cc1cc(S(=O)(=O)N2CCC(c3cc(N)on3)CC2)ccc1F +CNc1snc(C)c1C(=O)N(C)Cc1cccc(OC)c1OC +COC(=O)c1ccc(OC(=O)Cn2c(=O)oc3ccccc32)cc1 +COc1ccc(OCC(=O)NCC2(C(N)=O)CCOCC2)cc1 +Cc1sc(NC(=O)CCc2ccsc2)c(C(N)=O)c1C +CCc1ccccc1OCC(=O)NCc1ccoc1 +CCOc1ccc2nc(NC3=NCCC(=O)N3)nc(C)c2c1 +Cc1ccnc2nc(-c3ccc(F)c(F)c3F)[nH]c12 +Cc1csc(=O)n1CCC(=O)Oc1ccc(Br)cc1 +NC(=O)c1ccc(Cl)c(NC(=O)CCSc2ccccn2)c1 +CCC(CC)NC(=O)C(C)NC(=O)c1ccco1 +CCCCNC(=O)C1CCN(C(=O)Nc2cccs2)CC1 +Nc1cncc(Cc2cccc(Br)c2)c1 +COc1ccccc1OCC(=O)Nc1nc(-c2ccncc2)cs1 +NS(=O)(=O)c1cccc(CNC(=O)CCOc2ccccc2)c1 +CC(C)c1ccsc1C(=O)OCCN1CCCC1=O +COC(=O)C(CC(C)C)NC(=O)Cn1c(=O)cnc2ccccc21 +CS(=O)(=O)Nc1ccc(S(=O)(=O)Nc2ccc(F)cc2)cc1 +COc1cc2cc(C(=O)NC(C)c3ccccc3)[nH]c2cc1OC +CCCn1nc(-c2ccc(OCC)c(F)c2)cc(CO)c1=O +COc1ccc(CCc2nc(C3CN(C)CCO3)no2)cc1 +CCOc1ccccc1-c1nc2ccccn2c1C(C)O +Cc1cc(F)ccc1-n1ccc(C(=O)NC2CCN(C(N)=O)C2)n1 +COc1ccc(CC(=O)Nc2nc3nc(C)cc(O)n3n2)cc1 +COCc1c(C(=O)Nc2cc[nH]n2)sc2cccc(F)c12 +CC(C)c1nc2scc(-c3cccnc3)n2c1CC#N +Cn1nnnc1SCC(=O)NC(c1ccccc1)c1nccs1 +NS(=O)(=O)Cc1ccc(NC(=O)CC2CCCC2)cc1 +C#CCOC(=O)c1ccc(S(=O)(=O)Nc2ccccc2)cc1 +O=C(CSc1nc(C2CCCC2)n[nH]1)N1CCCc2ccccc21 +CN(CCCNc1cc(C#N)ccn1)c1ccccc1 +COC(=O)C(C)(C)NC(=O)C1CCN(c2ccc(F)c(F)c2)C1=O +O=S(=O)(Nc1ccc(CCO)cc1)c1ccc(F)cc1 +CCCCNC(=O)C1(c2cc(-c3ccco3)on2)CC1 +O=C(CCCn1sc2ccccc2c1=O)Nc1ccccn1 +Cc1cc(NC(=O)C2(c3ccccc3)CCOCC2)nc(C(C)C)n1 +CSc1ccc(C(O)CNC(=O)c2ccc(C)cc2)cc1 +O=S(=O)(NCc1nnc2n1CCCCC2)c1cn[nH]c1 +COc1ccc(OC)c(C(C)NC(=O)C2CCOC2)c1 +CCN1CCC2(CCC1=O)CN(C(=O)c1ccc[nH]1)CCN2C +CC1COCCN1C(=O)NCc1cccnc1-n1cncn1 +N#Cc1ccccc1Cn1nnc(-c2ccccc2Br)n1 +CCOCCCNS(=O)(=O)c1cc(C)sc1C +Cc1ccc(C(CNC(=O)c2cc(Cl)c[nH]2)N2CCOCC2)o1 +CCc1cc(C2CCCN2C(=O)c2cc(C)on2)on1 +COc1ccccc1SCc1ccn(C)c(=O)c1 +Cc1ccccc1OCCOCCn1cnc2ccccc21 +Cc1ccc(C)c(NC(=O)CN(C)c2ncnc3c2cnn3C)c1 +CSc1nc2ccccc2c(=O)n1CC(=O)C(C)(C)C +Cc1nn(-c2ccccc2)nc1C(=O)Nc1sccc1C#N +Cc1ccc(Cn2c3c(cc(C#N)c2=O)CNCC3)cc1 +CCCn1cc(NCC2CCCN(C(=O)OC(C)(C)C)C2)cn1 +CC(C)C(C)(C#N)NC(=O)CN1CCc2ccccc21 +Cc1ccc(CCNC(=O)NC(c2ccccc2)c2nccn2C)cn1 +CCCC(=O)N1CCCCC1C(=O)N=c1sccn1C +CC1(C(=O)OCc2ccccn2)Cc2ccccc2C(=O)O1 +CCNC(=O)c1cnc(CC2CCCN(C(C)=O)C2)cn1 +CCCCNC(=O)c1c[nH]c2c(C)cccc2c1=O +CC(C)CC(O)CNC(=O)NCC1(c2ccc(F)cc2F)CC1 +COc1ccc(CNC(=O)c2cc(-c3ccco3)[nH]n2)cn1 +CC(NC(=O)Cn1cc(Br)ccc1=O)C1CCCO1 +Cc1cc(NC(=O)c2ccoc2)n(-c2ccccc2F)n1 +CC(NS(=O)(=O)c1cnn(C)c1)C(=O)N(C)c1ccc(F)cc1 +O=C(Cc1ccc[nH]1)Nc1ccc(OC2CCOC2)cc1 +Cc1cc(C)n(CC(=O)N2CCC(c3cc[nH]n3)C2)n1 +COC(=O)CCc1cc(C)ccc1S(C)(=O)=O +Cc1cccc(-c2noc(-c3ccc(=O)[nH]n3)n2)c1 +NC(=O)c1ccc(NCc2cccc(OCC(F)(F)F)c2)cc1 +COc1ccc(C2CC(=O)c3cc(N)c(C)c(C)c3O2)cc1 +N#Cc1nnn(Cc2ccccc2F)c1-c1cccc(F)c1 +Cc1cc(C)c2c(Br)c(OCc3nnc(C)o3)ccc2n1 +COc1ccccc1CC(C)NCc1c[nH]nc1C +c1ccc(-c2ccc3c(c2)C(c2ccnnc2)NCC3)nc1 +COc1cc2[nH]c(=O)c(CO)cc2c(OC)c1OC +CC(C)CN1CCN(Cc2cnc3cc(O)ccc3c2)C(C)C1=O +Cc1ccc2c(c1)OCCN2Cc1cn(C)nc1C +CC(NC(=O)COc1ccccc1)c1ccc(S(C)(=O)=O)cc1 +N#Cc1ccc(OCCOC(=O)c2cc(N)cc3ccccc23)cc1 +CCn1cc(Br)cc1C(=O)N(C)Cc1ccsc1 +Nc1cccc(Cl)c1N(CCO)C1CCCC1 +COCCCNc1nc2nonc2nc1N1CCCC(OC)C1 +O=C(CSc1ncn[nH]1)NC1CCc2c(F)cccc21 +Cc1cc(C(=O)Nc2nc3c(s2)CN(C)CC3)nn1C(C)C +COc1ccc(OCC(=O)Nc2ccc(N(C)C(C)=O)cc2)cc1 +Cn1c(=O)n(Cc2ccco2)c(=O)c2c3c(sc21)CCCC3 +NS(=O)(=O)N1CCN(Cc2cccnc2)CC1 +O=C(Cc1cccs1)Nc1ccc2c(c1)COC2 +CN(C(=O)CNC(=O)c1ccccc1)c1ccc2ccccc2c1 +CCN(CC)C(=O)COc1ccc(NC(N)=O)cc1Cl +CCOC(=O)CNC(=O)C1CC(=O)N(C2CCCCC2)C1 +CC(C)NC(=O)CNC(=O)c1nc(-c2ccc3cc[nH]c3c2)no1 +O=C(COc1ccccc1Cl)Nc1ccc(Cl)cn1 +CCN(CC)C(=O)Cc1noc2c(C)cc(N)cc12 +COc1ccc(NC(=O)Cc2ccc(C)cc2)cc1OC +COc1ccc(-c2noc(CC(=O)N(C)c3ccccc3)n2)cc1 +CCc1csc(C2CCCN(C(=O)CC3C=CCC3)C2)n1 +Cc1ccc(NC(=O)COC(=O)Cn2cnnn2)cc1 +Cc1nn(C)c2oc(N)c(-c3cccc(C(F)(F)F)c3)c12 +CNC(=O)C1(C)CN(C(=O)c2ccncc2)CCO1 +COc1cc(C(C)C)ccc1NCCN1CCOCC1 +O=C(NCC(O)c1c(Cl)cccc1Cl)c1cccnc1 +CS(=O)(=O)N1CCc2cc(C(=O)N(C3CCCC3)C3CC3)ccc21 +Nc1cccc(Cl)c1NC(=O)c1c(F)cccc1F +c1cncc(-c2cccc(-c3ccn(CC4CCCO4)n3)c2)c1 +OC1CCC(Nc2cc(-c3ccccc3)nc3ccnn23)CC1 +COc1ccnc(NC(=O)Cc2cn(C)c3ccccc23)c1 +O=C(NCCN1CCOCC1)C1CC(=O)N(c2ccc(O)cc2)C1 +COCc1ccccc1C(=O)C(C#N)c1ccc(C(F)(F)F)cn1 +Cc1noc(N)c1C(=O)OC(C)C(=O)NCc1ccc2c(c1)OCO2 +CCC(C)NC(=O)CN1CCN(C(=O)C2CCC(=O)N2)CC1 +O=C1c2cnc(N3CCC(O)CC3)nc2CN1Cc1ccc(F)cc1 +CCc1c(C)sc(NC(=O)c2cc(OC)ccn2)c1C#N +COc1ccc(C(=O)C(C)OC(=O)c2[nH]c(C)c(C(C)=O)c2C)cc1 +COc1ccc(Cl)cc1NCc1cc2cc(C)ccc2[nH]c1=O +COC(=O)CCN(C)C(=O)Cc1cccc(O)c1 +CCCC(=O)N(C)c1ccc(Br)cc1C +O=C(NCC1(N2CCOCC2)CCCCC1)N1CCC1 +Cc1cc(NC(=O)NC(C)Cn2cncn2)c2ncccc2c1 +COc1ccc(Cl)cc1N(C)C(=O)c1ccnc(F)c1 +COc1cccc(CNC(=O)c2cc(OC)ccc2O)c1 +Cc1ccc(C(=O)N2CCN(CCOc3ccccc3)CC2)c(=O)[nH]1 +Cc1cc(OC(=O)C2CC2)c2c3c(c(=O)oc2c1)CCC3 +COC(=O)c1cc(N)ccc1NCc1nccs1 +CNC(=O)c1cccc(NC(=O)c2cnn(-c3ccncc3)c2C)n1 +CC(Cn1cncn1)NC(=O)C(C)Nc1ccc(Cl)cc1Cl +CCOC(=O)NC1(NC(C)(C)C)Oc2ccccc2O1 +CS(=O)(=O)c1ccc(Nc2c(F)cc(N)cc2F)cc1 +Cc1nc2ccc(C(=O)NCC3(c4ccccc4)CC3)cc2nc1C +Cc1ccc(C(=O)CSc2nccc(=O)[nH]2)cc1 +CCOC(=O)c1cc(-c2c(C)cc(OC)cc2C)nn1CCO +CN(Cc1cnc(N)nc1)C(=O)C1(c2ccc(F)cc2)CC1 +Cc1cc(N2CCC(c3cc4cccnc4[nH]3)C2)ncn1 +NC(=O)c1cccnc1Nc1ccc(Cl)cc1Cl +CC(C)(C)C(=O)Nc1ccc2c(c1)N(C(=O)C1CC1)CC2 +Nc1cc(N)nc(SCc2c(F)cccc2Cl)n1 +COC(=O)c1cccc(S(=O)(=O)N(C)C(C)c2ccccn2)c1C +CC(c1ccc(F)cc1)n1c(CO)nc2ccccc21 +COc1ncccc1CNC(=O)Cc1c[nH]c2ccccc12 +CCOc1ccccc1C(CC(=O)Nc1ncc(C)s1)NC(C)=O +O=c1ccc(-c2ccc(F)cc2)nn1CC(O)c1ccc(Cl)cc1 +CCc1ccc(C2COCCN2Cc2ccc(C)o2)o1 +O=C(c1cnn2cccnc12)N1CCCC1C1CCCCC1 +Cc1ccccc1Cc1nc(-c2cnccn2)no1 +CN(Cc1cccnc1)C(=O)c1ccc2c(c1)CCC2 +Cc1ccoc1C(=O)Nc1nc(C(C)C)cs1 +CC(C)CNC(=O)CSc1nnnn1-c1ccccc1 +CC(CC(=O)NC(Cc1ccccc1)C(=O)N1CCCC1)C1CC1 +Cc1ncsc1CN1CCN(C(=O)Cc2cccc(Cl)c2)CC1 +CCn1cnnc1CNC(=O)NC(C)c1cccs1 +CCCc1csc(NC(=O)CNC(=O)c2ccc(F)cc2F)n1 +CC(OCC1CC1)C(=O)N1CCC(Oc2cccc(Cl)c2)C1 +CC(=O)Nc1ccc(C(=O)Nc2ccc(Br)c(C)c2)cc1 +CNC(=O)CNC(=O)C1CCCN1C(=O)Cc1ccccc1 +Cc1cc2ncn(CC(=O)N3CCCCC3C)c2cc1C +CNS(=O)(=O)c1ccc(C(=O)NC(C)c2ccncc2)cc1 +Cc1cccn2c(CN3CCNC(=O)C3c3ccccc3)cnc12 +Cc1nc(-c2ccsc2)sc1C(=O)NCCc1cnn(C)c1 +COCCNC(=O)CCC(=O)c1ccc2c(c1)CCC2 +CC(=O)Nc1ccc(Sc2nncs2)cc1 +CC(NC(=O)NC(C)c1nncn1C)c1ccc(F)c(Cl)c1 +Cc1cc(C(=O)NCC2CCCO2)c2c(=O)n(C)c(=O)n(C)c2n1 +COc1coc(COc2ccc(SC)cc2)cc1=O +C=CCOc1cccc(NC(=O)N(C)Cc2nccn2C(F)F)c1 +CC(C)(CO)Nc1ccc(-c2nc(-c3ccccc3F)no2)cn1 +CCOC(=O)c1ccc(Nc2nnc3nc(C)cc(C)n23)cc1 +COC(=O)c1c(NC(=O)c2cc(N)ccn2)sc(C)c1C +Cc1cc(NC(=O)CSc2cc(-c3ccccc3)ncn2)no1 +COC(=O)NCC(=O)N1CCC(c2cc(OC)ccc2OC)C1 +O=C(NCc1cnn2cccnc12)c1cnc(-c2cccnc2)nc1 +Cc1nc2ccccc2n1CCNC(=O)c1cnccn1 +O=C(CSc1ccccn1)NCCc1c(F)cccc1F +COCc1cc(C(=O)NCc2ccc(-c3ccccc3F)o2)no1 +CCCOc1ncccc1C1OC(C)(C)C(C)(C)O1 +CCC1COCCN1C(=O)c1cc(-c2cccn2C)n[nH]1 +C=CCNC(=O)c1nnn(-c2ccc(OC)cc2)c1COC +CCNC(CCN1CCOC(C)C1)c1ccccc1 +Cc1ccc(C)c(OCCC(=O)Nc2nc(C)cs2)c1 +COc1ccc(-c2ccc(F)cc2)n2nc(N)nc12 +CCOC(=O)c1nsc(C(=O)NCc2ccccn2)c1N +CCn1cc(C(=O)Nc2ncccc2C)c(=O)c2cc(OC)ccc21 +O=C1CC(c2ccco2)Cc2[nH]c(=O)c(C(=O)NCC3CC3)cc21 +O=C(NCCc1ccc2c(c1)OCO2)c1nnc2ccccc2n1 +Cc1cccn2c(=O)c3cc(C(=O)NCc4ccccn4)n(C)c3nc12 +Cc1ccccc1CNC(=O)c1ccc2ccccc2n1 +CS(=O)(=O)c1ccc(F)c(NC(=O)CCc2ccco2)c1 +C=CCNC(=O)C(C)Sc1ccc(Cl)cc1 +Cc1nc(C(=O)Nc2cc(CC3CCCCC3)n[nH]2)c(=O)[nH]c1C +CCOCCOCC(=O)Nc1ccc(F)cc1N +CCN(CCc1ccccc1)C(=O)Nn1cnc2ccccc21 +CC(C)N(C(=O)Cc1noc2ccccc12)C1CCC1 +COc1ccc(OC)c(NC(=O)N(C)Cc2ccnn2C)c1 +CSc1ccc(C(=O)Nc2nnc(-c3ccsc3)o2)cc1 +Cc1ccc(Cn2nnc(C(=O)N3CCCC3)c2-n2cccc2)cc1 +COc1c(C(=O)NCc2cnn(C)c2)sc(C)c1Br +CC(=O)NC(C(=O)NCC1(c2ccc(F)cc2F)CC1)C(C)C +NC(=O)CSc1ccc(CC2CCCO2)cc1 +O=C(CCn1ccnn1)Nc1n[nH]c2ccccc12 +CN(Cc1cccc(F)c1)C(=O)C1(C#N)CCCCC1 +CCn1c(=O)n(Cc2nc(C3CC3)no2)c2ccccc21 +Cc1cnc(-c2nnc(NCC3CCCO3)s2)cn1 +Cc1cc(-c2cncnc2C2CCCN(Cc3cscn3)C2)on1 +Cc1cc(C)c(C)c(S(=O)(=O)N(C)CC(C)(CO)CO)c1C +CC(C)COC(=O)c1ccccc1SCC(=O)N1CCCC1 +Cc1nnc(SC(C)c2ccc(C(F)(F)F)cc2)n1N +OCC1CCCN1c1cc(N2CCc3sccc3C2)ncn1 +O=C(c1n[nH]c2c1CCC2)N1CCN(CCO)CC1 +Cc1cc(C(=O)NC2CCCCC2)ccc1NC(=O)c1ccccn1 +COC(=O)c1cc(N2CCOCC2)ccc1NC(=O)c1cccs1 +O=C(CSc1ccc(Cl)cc1)N1CCOCC(CO)C1 +COc1ccc(OCCNC(=O)c2ccc(F)c(F)c2)cc1 +CNC(=O)C(C)(C)c1cccc(Br)c1 +O=C(c1cnc2ccc(F)cc2c1O)N1CCc2ccccc21 +CCn1c(C(=O)Nc2cnn(C(C)C)c2)cc2sccc21 +CC(=O)N1Cc2ccccc2C2CN(C(=O)c3cccc(N)n3)CC21 +c1ccc(-c2n[nH]cc2CNCCc2nnc3ccccn23)cc1 +Cc1ncsc1C(=O)N1Cc2ccccc2OC2(CCOCC2)C1 +CCNC(=O)CN(CC)C(=O)C(C)(C)Oc1ccc(Cl)cc1 +N#Cc1nncn1CC(=O)N(Cc1ccc(F)cc1)C1CCCCC1 +Cc1ccccc1S(=O)(=O)N(C)c1ccc(Cl)c(N)c1 +O=C(NCCc1ccsc1)c1c(F)cccc1Cl +COc1cc(C(C)=O)ccc1OCc1noc(-c2ccsc2)n1 +O=C(COc1ccccc1F)NCCNC(=O)C1CC1 +CCc1nc(C2CCCN(C(=O)c3cn(C)nc3C)C2)no1 +Cc1noc(C)c1S(=O)(=O)Oc1ccc(C(C)C)cc1 +Cc1ccc(C)c(S(=O)(=O)N(C)Cc2ccoc2C)c1 +CCCOc1ccc(C(=O)Nc2ccccc2C#N)cc1 +O=C1CCN(S(=O)(=O)c2cccc(Cl)c2)CCN1 +COCC(=O)Nc1ccc(N(C)C(=O)c2ccc(Cl)cc2)cc1 +O=C(NCCn1cnc2ccccc21)c1csnn1 +Cc1ccc(CC(=O)N2CCOCC2CC(=O)c2ccccc2)cn1 +O=C(Nc1ccc2oc(-c3ccccc3F)nc2c1)c1nc[nH]n1 +COCCCC(=O)Nc1nc(CN2CCOCC2)cs1 +CCc1nnsc1C(=O)NCc1nnc2n1CCC2 +O=C(OCc1cccc(F)c1)c1ccc(-n2cncn2)cc1 +CCC(C)NC(=O)CCC(=O)c1ccc(OC)c(N)c1 +Cc1ccc(N2CC(C(=O)NC3CCCCC3)CC2=O)cc1Cl +Cc1ccn2cc(C(=O)N(C)C3(C#N)CCC3)nc2c1 +CCOC(=O)c1ccc(N2CCCN(C(=O)c3ccoc3)CC2)nc1 +COc1ccccc1N1CCC(C(=O)NCC(C)C)C1=O +CN(Cc1ccc(Oc2ccccc2)cc1)C(=O)c1ccn(C)n1 +COc1cccc(CC(=O)Nc2ccccc2-n2ccnc2)c1 +CCC(C)NC(=O)c1ccc(NC(=O)C2CCCC2)cc1 +CC(C)NC(=O)N1CCCC1c1nnn2cc(C3CC3)ccc12 +CC1CCCC(C)N1C(=O)CSc1nnc(C(C)(C)C)n1N +COc1ccccc1NC(=O)CC1C(=O)Nc2nc(C)nn21 +c1cc(-c2nc3sc4c(n3n2)CCNC4)ccn1 +Cc1nn(C)cc1C(=O)N(CCC#N)CCC(F)(F)F +CC(=O)NCc1ccc(-c2csc(NC3CC3)n2)s1 +COc1ccc(-c2noc(COC(=O)c3cccs3)n2)cc1 +Cc1nc(C(=O)Nc2ccc(F)cc2)n2ccccc12 +Cc1cccc(N2CCN(C(=O)NCCCn3cncn3)CC2)c1 +COc1c(F)cc(NC(=O)COc2ccccc2)cc1F +N#CCCC(C#N)Cn1cnc2sc(-c3ccccc3)cc2c1=O +O=C(Cc1cccs1)Nc1c(O)cccc1F +CN(Cc1ccccc1)C(=O)c1ccc2c(c1)ncn2C1CCCC1 +COc1ccc(C(=O)NCc2ccc(C)n2C)cn1 +COC(=O)c1ccc(NC(=O)C2CCCC2)s1 +C=CCOC(C)C(=O)Nc1ccc2nc[nH]c(=O)c2c1 +Cc1ccc(NC(=O)C2CCCN2C(N)=O)cc1F +COc1ccc(-c2cc(C#N)c(NC(=O)c3ccco3)o2)cc1 +COC(=O)C(NCc1ccc(SC)cc1)C(C)C +CC(C)N1CCC2CN(c3ncccn3)CC2C1=O +COc1ccc(CNC(=O)NCc2ccc(C)s2)cc1 +Clc1cc(Cl)cc(NCc2cccnc2)c1 +COc1ccc(NC(=O)NC(C)c2ccncc2)cc1C +Cc1cc(N)ccc1NC(=O)CCOCC(C)C +CCN(C)C(=O)c1cccc(C(=O)Oc2cccc(-n3cccn3)c2)c1 +CCc1ccc(Oc2ncnc(N3CCCC3)c2N)cc1 +O=C(CCc1ccsc1)NCCOc1cccnc1 +COc1ccc(NC(=O)c2cnc(C)c(N)c2C)cc1 +COCCNC(=O)CC1CCN(C(=O)NC2CCCCC2)CC1 +Cc1ccc(NC(=O)C2CC2)cc1NCC(=O)N1CCCC(C)C1 +CC(C)CCC(C)NC(=O)c1c[nH]c2ccccc2c1=O +N#Cc1cccc(S(=O)(=O)N2CCN(CC(F)F)CC2)c1 +CC(C)(C)n1cc(C(=O)Nc2ccc3c(c2)NC(=O)CS3)cn1 +C#CCN1CCN(CC(=O)N(CCC)CCC)CC1 +CCOc1ccccc1C(=O)Cn1cc(Br)cn1 +COc1ccc(Nc2nc(OC)nc(OC)n2)cc1 +CC(C)Cc1nc2cc(Br)cnc2n1CC#N +C=CCN1CCC2(CCN(C(=O)c3ccco3)CC2)C1=O +CCS(=O)(=O)Nc1ccc(N(C)C(C)=O)cc1 +Cc1cc2nc(C(C)C)cc(NCc3cnn(C)c3C)n2n1 +CCCNC(=O)Nc1cc(S(=O)(=O)N(C)C)ccc1N(C)C +Cc1nc2ccc(NC(=O)COCC3CC3)cc2o1 +Cc1cc(C)c(S(=O)(=O)N2CCN(C(=O)N(C)C)CC2)c(C)c1 +COc1cc(NC(=O)Nc2cccc(C#N)c2)cc(OC)c1 +CN(C)C(=O)COC(=O)c1sc2cc(F)ccc2c1Cl +COc1ccc(NC(=O)CC2CCCO2)cc1Br +Cn1cc(S(=O)(=O)NC2CCc3ccccc32)cn1 +CCOc1ccc(OCC)c(NC(=O)c2cc(C)oc2C)c1 +COc1cc(C(=O)Nc2cc(Cl)ccc2C(N)=O)ccc1C +Cc1ccc(C)c(NC(=O)CN(C)C(=O)c2cnn(C(C)(C)C)c2)c1 +CCOC(=O)C1CCCN(C(=O)Nc2c(F)cccc2F)C1 +CCC(=O)N1CCCN(C(=O)c2cccc3cn[nH]c23)CC1 +O=C(NCc1ccccc1)c1cc2cc(O)ccc2oc1=O +CC(=O)NCCNS(=O)(=O)c1cc(N)ccc1Cl +COC(=O)c1c(C)[nH]c(C(=O)CN(C)CCC#N)c1C +COC(=O)c1ccc2c(c1)CCN2C(=O)CCc1ccc(C#N)cc1 +Cc1ccnc(NC(=O)c2cc3c(=O)n(C)c(=O)n(C)c3s2)c1 +Cc1onc(-c2ccncn2)c1C(=O)NCc1cccs1 +Cc1nc(-c2ccco2)ccc1C(=O)NCC(N)=O +CC(C)(C)Sc1cc(C(=O)N2CCC(n3cccn3)CC2)ccn1 +CCN(Cc1cccc(F)c1)C(=O)C1Cc2ccccc2C(=O)O1 +Cc1cc(Br)ccc1C(=O)Nc1nccs1 +CCC1CCCCN1C(=O)CSc1nc(N)c(C#N)cc1C#N +Nc1ccc(NC(=O)CN2CCCC2=O)c(Br)c1 +CC(Sc1nnc(CCC(N)=O)n1C)C(=O)c1ccc(F)cc1 +CCC(C)Oc1cc(C(=O)NC(C)(C)C#N)ccn1 +Cn1ccnc1CNC(=O)C1CCC(=O)N(C2CCCC2)C1 +Cc1noc(C)c1C(=O)OCC(=O)N(CCC#N)c1ccccc1 +O=C(Cn1ncc2c(=O)oc3ccccc3c21)NC1CCCCCC1 +CC(C)c1csc(NC(=O)C2Cc3ccccc3O2)n1 +Cc1cccc(NC(=O)NC2CC(=O)N(Cc3ccccc3)C2)c1C +COC1CCCC1OC(=O)c1nc2ncc(Br)cn2n1 +CCc1ccc(Oc2ccc(S(N)(=O)=O)cc2)cc1 +COc1ccc(CCN2CCCCS2(=O)=O)cc1Cl +Cc1cc(Cl)cn2c(N)c(-c3cccs3)nc12 +CC(=O)N1CCN(c2ccccc2Cl)C(=O)C1C +CCOC(=O)N1CCC(NC(=O)NC2CCCC(C)C2C)CC1 +CCc1nc(NC(=O)N2C3CCCCC2CCC3)nn1C +CC1CC1c1ccc(CNc2cccc(C#N)c2)o1 +CN(C)C(=O)Cc1ccc(-n2c(=O)[nH]c3ccccc3c2=O)cc1 +Cn1cc(CNC(=O)C2CCN(C(=O)Nc3ccccc3)CC2)cn1 +CC(C)CCNC(=O)c1ccc2c(c1)NC(=O)C(C)N2 +Cc1ccc(SC(C)C(=O)N(C)Cc2snnc2C)cc1 +COc1cc(C)ccc1OS(=O)(=O)c1ccc(F)cc1F +O=C(c1cccs1)N1CCN2C(=O)C3CCCN3C(=O)C2C1 +CCC(C)C(=O)N1CCN(Cc2nc(-c3cccs3)no2)CC1 +CC(=O)c1ccc(OC(C)C)c(NC(=O)COc2ccccc2)c1 +CC(=O)N1c2ccccc2CC1C(=O)NC1CCCCCC1 +Cc1cccc(C)c1NCc1cc(C#N)ccc1F +Cc1cc(OCC(=O)NCC(O)c2ccc(F)cc2)ccc1Cl +Cc1cc(C(=O)Nc2c[nH]nc2-c2ccccc2)ccc1F +COc1ccc(OC)c(-n2nc(C)c(CO)c2C)c1 +CC(C)CNC(=O)NCc1nnc(C(=O)Nc2ccccc2)s1 +Cn1c(=O)n(C)c2cc(COC(=O)C3CCCN3)ccc21 +CC(C)(C)C(NC(=O)c1ccc(Br)c(F)c1)C(N)=O +C=CCCOC(=O)c1sc2nc3n(c(=O)c2c1C)CCCCC3 +O=C1CN(C(=O)COc2cc(F)c(F)cc2F)c2ccccc2N1 +O=C(Nc1nc2ccccc2s1)c1ccccn1 +CCOC(=O)COc1nc(C)c(Br)c(OC)n1 +Cc1ccc(NC(=O)c2cc(N)cnc2C)c(Cl)c1 +CC(CO)NC(=O)Nc1cccc(C(=O)N2CCc3ccccc32)c1 +COC(=O)CCNc1nn2c(nc3cc(Br)ccc32)[nH]1 +C=CCc1cc(C(=O)NC(C)c2ncc(C)o2)cc(OC)c1OC +CN(CCO)C(=O)CCOc1cccc(Cl)c1 +CCc1c(C)nc(SCC(=O)NCc2cccnc2)[nH]c1=O +CC(C)(C)OC(=O)Nc1ccc(NC(=O)C2CC2)cn1 +O=C1CN(C(=O)CCc2ccc(-c3ccccc3F)o2)CCN1 +Cc1ccc(NC(=O)N(C)Cc2cnccn2)c(C)c1 +Fc1cc(F)cc(-c2oncc2-c2nnnn2-c2ccccc2)c1 +Cc1nc2c(s1)C(N(C)C(=O)CCSc1ccccn1)CCC2 +CCN1CC(C(=O)N2CCCN(c3ccc(F)cc3)CC2)CC1=O +CC(C)CNc1ccc(S(=O)(=O)C(F)F)cc1 +CCC(=O)N1CCc2cc(C(=O)N3CCCS3(=O)=O)ccc21 +Cc1nnc(SC(C)C(=O)Nc2ccc3ccccc3c2)s1 +CC(C)CC(=O)Nc1ccc2c(C(C)C)cc(=O)[nH]c2c1 +COc1coc(COC(=O)c2scnc2C2CC2)cc1=O +CC1CN(C(=O)CSc2nnc(C3CC3)n2C)CC(C)O1 +CNC(=O)c1cc(Cl)c(=O)n(Cc2ccc(Cl)c(Cl)c2)c1 +N#Cc1cnc(SCc2ccc(Br)cc2)nc1N +CCc1cc(C(=O)OC)c(NC(=O)C2CCN(C(C)=O)CC2)s1 +O=C1CN(C(=O)c2nc(-c3cccs3)no2)CCN1 +COc1ccc(OC)c(S(=O)(=O)NCC2CCCO2)c1 +CNC(=O)c1cccc(NC(=O)c2csc(C)n2)c1C +CCCCNC(=O)Nc1cc(-c2ccccc2)nn1CCO +COCC(C)(O)CNS(=O)(=O)c1cc(C)c(C)cc1OC +Cc1nnc(SCC(=O)Nc2ccc(Br)c(C)c2)o1 +COc1ccc(OC)c(NC(=O)CCc2ccccc2)c1 +COc1cc(C)c(Cl)c(C)c1C(N)C(F)(F)F +CCn1c(-c2ccc(OC)c(Cl)c2)ccc(C(C)=O)c1=O +N#CCCCn1c(C(Cl)(Cl)Cl)nc2ccccc21 +C#Cc1cccc(NS(=O)(=O)c2ccc(NC(=O)CC)cc2)c1 +C=CCNc1cc(-c2cccc(C(F)(F)F)c2)nc(C)n1 +COC(=O)C(CO)Nc1nc2c(Cl)c(C)nn2c2ccccc12 +CCC(C)C(=O)NCc1cccc(NC(=O)N2CCCC2)c1 +Cc1ccc(-c2csc(Nc3ncccn3)n2)o1 +COc1ccc(OCCCC(=O)N2c3ccccc3CC2C)cc1 +CC(=O)c1cnc(NC(=O)c2cnc3ccc(C)cn23)s1 +Cc1ncc(CNC(=O)Cc2cccc(O)c2)s1 +O=C(Nc1cc(Cl)ccc1-n1cncn1)C1CC1(Cl)Cl +O=C(Cc1ccc2ccccc2c1)N(CCO)Cc1ccccc1 +O=C(Nc1nn2c(-c3ccccc3)nnc2s1)c1ccc(F)cc1 +CCc1onc(C)c1NC(=O)N1CCCC(OC)C1 +CN1CCN(C(=O)c2c(N)oc3ccc(F)cc23)CC1 +CC(C)CNC(=O)CCCS(=O)c1ccc(Br)cc1 +CCc1nnsc1C(=O)NCc1cccc(C)c1 +O=C(NCc1ccc(F)cc1)Nc1cnn(Cc2ccccc2)c1 +Cc1ccc(S(=O)(=O)CC(=O)N(C)Cc2ccccc2C)cc1C +CCC(=O)c1ccc(OCC(=O)NCc2ccco2)c(N)c1 +CC(C#N)N1CCN(c2ccc(C(N)=O)cc2)CC1 +C#CCC(OC(=O)c1cc(N2CCNC2=O)ccc1F)C1CC1 +CCc1cccc(CC)c1NC(=O)CS(=O)(=O)c1nccs1 +N#Cc1ncc(C(F)(F)F)cc1OCc1cccnc1 +COC(=O)CN(C(=O)Cc1cccc(Br)c1)C(C)C +COCCCNC(=O)c1c(-c2ccccn2)noc1C +C#CCNC(=O)CNC(=O)c1ccc(C(C)(C)C)cc1 +CCCc1sc(C(=O)NCCc2nc[nH]n2)cc1CC +CC(C)c1ccc2c(c1)C(c1cnn(C)c1)NCC2 +CCc1ccc(S(=O)(=O)N2CC(c3nc(C)no3)C2)cc1 +CCCOc1ccccc1OCC(=O)N1CCCCCC1 +COc1ccc(F)c(NC(=O)COc2ccc(C)cc2OC)c1 +CCS(=O)(=O)c1ccccc1C(=O)NC1CCCCC1O +CS(=O)(=O)c1ccc(NC(=O)OCC(F)(F)F)cc1 +CCc1cc(C(=O)N2CCCC2C(=O)N2CCN(C)CC2)sc1C +COc1ccccc1OCC(=O)N1CCOCC1 +CCN(CC)C(=O)c1ccc(S(=O)(=O)NC)o1 +COc1cccc(C(=O)N(C)c2cccc(C)n2)c1F +O=C(Cn1ncccc1=O)Nc1nc2ccccc2[nH]1 +CCOC(=O)c1c(C)[nH]c(C(=O)OCC(F)(F)F)c1C +Cc1c(N)cccc1NC(=O)CCCOCCO +CCc1nnc(NC(=O)c2cc(=O)oc3cc(OC)ccc23)s1 +CC(=O)Nc1cc(NCc2csnn2)ccc1F +COc1ccc(Cl)cc1N1CC(CO)CC1=O +CNC(=O)c1ccc(NC(=O)N(C)CCC(C)C)cc1 +CC(C(=O)N(C)CCC#N)N1CCOC(c2ccc(Cl)cc2)C1 +Cc1nnc2c(Nc3ccc(Cl)cc3)nc3nonc3n12 +CCOc1ccc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c(C)c1 +CCC(Sc1nc(C)cc(=O)[nH]1)C(=O)Nc1ccccc1C#N +COc1ccc(C(=O)N2CCC(NC(=O)C3CCCCC3)CC2)cc1 +Nc1cccc(S(=O)(=O)Nc2ccc(F)c(F)c2)c1 +NC(=O)c1cc(NCC(=O)Nc2ccc3c(c2)OCO3)ccc1Cl +c1ccc(-c2ccnc3nc(N4CCOCC4)nn23)nc1 +CN(C)c1cccc(C(=O)NCc2ccc(F)cc2)c1 +Cc1nc(C)n(C2CCCN(C(=O)c3c(F)cccc3Cl)C2)n1 +O=C(NCc1nnc2n1CCC2)c1cccc(N2CCCC2=O)c1 +CCCNC(=O)Nc1ccc(S(=O)(=O)N2CCCC(C)C2)cc1 +COc1cccc(C(=O)N(c2nc(C)cs2)C2CC2)c1F +CC(CC#N)N(C)S(=O)(=O)c1ccc(F)cc1Br +Cc1ccc2c(c1)C1OCCCC1C(c1ccncc1)N2 +COc1cc(COc2nc(C(C)C)no2)ccc1SC +Cc1cc(NC(=O)c2cc(Br)cn2C(C)C)no1 +COc1ccc2c(c1OC)C(Cc1ccccc1O)NCC2 +COC(=O)C1Cc2c(ccc(OC)c2OC)C1=O +CCCCCNC(=O)C(C)Sc1ccccn1 +O=S(=O)(c1ccc(F)cc1)N1CCC(c2cnccn2)CC1 +Cc1csc(SCC(=O)Nc2cccc(N)c2)n1 +COc1c(C)cnc(CNC(=O)NCCC(C)C)c1C +CN(Cc1ccccc1)C(=O)CNc1ccc(Cl)cc1 +CCc1ccc(C(=O)NC(C)c2cc(C)oc2C)s1 +CC1CCCCC1N(C)C(=O)c1cn2ccccc2n1 +COc1ccccc1NS(=O)(=O)c1ccc(C)cc1OC +COc1ccc(NC(=O)CCC2C(=O)N=C(C)N=C2C)c(OC)c1 +Cc1c(C(=O)N(Cc2cccnc2)C(C)C)cnn1-c1ccncc1 +O=C(NC1CCCC1)c1ccc(=O)n(-c2ccccc2)c1 +Nc1nccc(N2CCCC(CCc3ccccc3)C2)n1 +CCNC(=O)c1cccc(NC(=O)c2cc(=O)c3ccccc3o2)c1 +CC(C)Oc1ccc(C(=O)Nc2ccccc2N2CCOCC2)cn1 +COc1cc(OC)c(NC(=O)CNC(=O)Cc2ccccc2)cc1F +CCNC(=O)c1c(C)nc(N)nc1-c1ccc(OCC)cc1 +Cc1cccnc1-c1cccc2c1OC(CNC(=O)C1(C)CC1)C2 +CCN(CCO)C(=O)CCc1nc(-c2ccc(C)c(F)c2)no1 +COc1ccc(C)cc1-n1nnc(-c2ccc(F)cc2)c1N +Cc1csc(NCc2ccccc2OC(C)C)n1 +CCOC(=O)c1cccc2nc(C(F)(F)F)[nH]c12 +CCc1nn(C)c(CC)c1S(=O)(=O)Nc1ccn(CC(F)F)n1 +COCc1c(C(=O)N2CC3C4CCC(CC4)C3C2)noc1C +CNC(=O)c1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +COc1cccc2cc(C(C)NC(=O)N3CCNC(=O)C3C)oc12 +CC(C)(C)Oc1ccc(CNc2cncnc2)cc1 +Cc1ccc(F)cc1NS(=O)(=O)c1ccc(N)cc1 +O=C(Nc1ccccc1)c1cc(-c2cc[nH]n2)ccc1F +CNC(=O)CN(C)S(=O)(=O)c1ccc2c(c1)OCCCO2 +Cc1ccc(CN(C)C(=O)CSc2nnc(C(F)(F)F)n2N)o1 +Cc1cccc(-n2nc(C)nc2C2CC(=O)OC23CCCCC3)c1 +CCS(=O)(=O)N(CCO)c1ccc(C)cc1C +Cc1nn(C)cc1C(=O)NCc1ccc(S(N)(=O)=O)cc1 +Cc1nnc2n1CC(NC(=O)c1ccc(-n3cccn3)cc1)CC2 +CCN1C(=O)CCc2cc(NC(=O)NCc3ccc(F)cc3)ccc21 +O=C(Cn1c(=O)sc2ccccc21)Nc1nc2c(s1)CCCC2 +CCOC(=O)C1CC(=O)N(c2ccc(OC)cc2)C1 +Cc1ccc(S(=O)(=O)N2CCCC(C(=O)N(C)C)C2)cc1 +COc1ccc(C)cc1NC(=O)NCc1noc2ccccc12 +COc1ccc(S(=O)(=O)N2CC(C)CC(C)C2)cc1OC +CC(C)CN(C(=O)Nc1cnn(CC(N)=O)c1)C(C)C +Cc1ccc(NC(=O)c2nn(-c3ccccc3)c(C)cc2=O)cc1 +Nc1ccc(Cl)c(NC(=O)CN2CCN(c3ccccc3)CC2)c1 +Cn1c(COc2cccc3cccnc23)cc(=O)n(C)c1=O +CCCN1C(=O)NC(c2ccc(O)c(OCC)c2)C(C(=O)OC)=C1C +COC(=O)CCC(=O)N1CCOC(CCc2ccccc2)C1 +COc1ncncc1NC(=O)N1CCC(Oc2cccc(Cl)c2)C1 +CC(C)NC(=O)CN(C)C(=O)c1cc(F)ccc1N +Nc1cc(F)c(Sc2nnc3n2CCCCC3)c(F)c1 +Cc1ccc(NC(=O)N2CCN(c3ccc(C)nn3)CC2)c(C)c1 +CCCC(=O)NCCN1CCN(C(=O)c2cccs2)CC1 +Cc1[nH]c(=O)n(C)c(=O)c1CCC(=O)NCc1ccc2c(c1)OCO2 +CC(C)COCCCNC(=O)N1CCN(c2ncccc2C#N)CC1 +O=C(NCCc1cccnc1)c1ccc2nccn2c1 +Cc1cc(C2CCC2)nc(N2CCN(C)C3(CCNC(=O)CC3)C2)n1 +CCCNc1ncccc1COCc1cccs1 +COc1ccnc(NC(=O)CCc2csc3nc(C)cn23)c1 +CCOc1ccccc1NC(=O)C(O)c1ccc(F)cc1 +CC(=O)N1CCC(CCOc2cccc(F)c2)CC1 +O=C(CCC1CCCO1)Nc1cccc2cnccc12 +Cc1nn(C)c(Oc2cccnc2)c1CN1CCOCC1CC(C)C +CC(C)S(=O)(=O)c1ccccc1NC(=O)N1CCCC(O)C1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)N(C(C)C)C1CCC1 +Cc1ccc(NC(=O)c2cc(C)nc3onc(C)c23)c(F)c1 +Cn1nccc1-c1nc2c3cnn(C)c3ncn2n1 +O=C(CN1CCN(c2ccccc2F)C1=O)NC1CCCCC1 +CCc1noc(CC)c1CNC(=O)NCc1ccccc1F +FC(F)(F)CN1CCCC(c2nc3ccccc3[nH]2)C1 +Cc1cc(C)c2c(C)c(C(=O)NC(C)C3CCCO3)sc2n1 +CC(C)NC(=O)NCC1CCN(S(C)(=O)=O)CC1 +COc1ccc2c(C)c(C(=O)NCc3ncc4c(n3)CCC4)oc2c1 +Cc1cc(C(=O)Nc2nc3c(s2)CC(C)CC3)n(C(C)C)n1 +COc1cccc(S(=O)(=O)C(C)c2nnnn2-c2ccccc2)c1 +O=C1c2ccccc2CS(=O)(=O)c2ccccc21 +Cc1ccc(C(=O)NC2CCN(C(=O)CC(C)C)CC2)c(C)c1 +Nc1cccc(Br)c1Cn1nc2ccccn2c1=O +O=C(NCCCn1ccnc1)C1CCN(C(=O)c2ccco2)CC1 +CC(=O)N1CCN2C(=O)C(Cc3ccccc3)NC(=O)C2C1 +CN(C)C(=O)COc1cccc(CNC(=O)Cc2cccs2)c1 +COCCN(Cc1ccncc1)C(=O)c1cccc(C(F)(F)F)c1 +Clc1cccc2c1CCNC2c1cnn2ccccc12 +CC1(C)C(NC(=O)NC2(c3ccccc3)CC2)C2CCOC21 +COc1ccnc(Sc2nnc(-c3ccccc3Cl)n2C)n1 +CCn1cc(C(=O)Nc2c(-c3ccncc3)nc3ccccn23)cn1 +NS(=O)(=O)c1cccc(NC(=O)NCCc2cccs2)c1 +CNC(=O)C(CC(C)C)NC(=O)c1nc2nc(C)cc(C)n2n1 +O=C(CNC(=O)c1cc2cccnn2n1)NC1CCCCC1 +CCC(C)NC(=O)C1CCN(c2ccc(Cl)cc2C)C1=O +CC1(C)C(=O)N(CCC(=O)N2CCOCC2)c2ccccc21 +CN(CC(=O)Nc1cccc(F)c1)C(=O)C1(c2ccccc2)CC1 +CCNC(=O)Cn1c(=O)oc2cc(Br)ccc21 +CCCNC(=O)C1CCN(C(=O)c2cnc(NC)nc2)C1 +Cc1ncsc1C(=O)N1CCC(c2nc3c(C)cccc3[nH]2)CC1 +CC(C)(Cc1ccccc1Cl)Nc1ccc2nnnn2n1 +CCOC(=O)N1CCC(C(=O)Nc2cccc(F)c2)CC1 +Cc1cc(NCc2ncc(-c3cccs3)o2)c(C(N)=O)cc1F +CCNC(=O)CNc1ncnc2c1cnn2-c1ccccn1 +CCn1cc(C(=O)NC(C)c2ccc(NC(N)=O)cc2)c(C(C)C)n1 +CNCC1NCCc2cccc(OC(F)(F)F)c21 +CCCC(=O)NCc1ccnc(OC(C)(C)C)c1 +COc1ccccc1Cc1cn2cc(C#N)ccc2n1 +CN(C)C(=O)c1ncn(CC(O)c2ccc3c(c2)OCO3)n1 +COC1CCN(C(=O)Nc2cnn(CC(N)=O)c2)CC1 +O=C(NCCOc1ccccc1)c1cccc(-n2cnnc2)n1 +CN(CCOc1ccccc1)C(=O)C1CC(=O)N(Cc2ccco2)C1 +COCc1nc2nccc(-c3ccc(Br)cc3)n2n1 +CCOCC1CCCN(C(=O)C2(C)Cc3ccccc3C(=O)O2)C1 +CCN(C(=O)CNC(=O)C(C)(C)C)C(C)c1ccc(F)cc1 +NC(=O)c1cc(C2CCCN(C(=O)CC3=CCCCC3)C2)n[nH]1 +Cn1ccc2ccn(CCOc3ccccc3C#N)c(=O)c21 +CS(=O)(=O)c1cccc(C(=O)N(Cc2ccc(F)cc2)C2CC2)c1 +CNS(=O)(=O)c1cccc(CNc2ccc(C#N)cc2F)c1 +CC(C#N)CN(C)c1c(F)c(F)c(F)c(F)c1F +CNC(=O)c1cccc(NC(=O)c2ccc(SC)cc2OC)c1 +O=C(Oc1ccc(S(=O)(=O)c2ccccc2)cc1)C1CCC1 +Nc1ccccc1S(=O)(=O)N1CCN(CCO)CC1 +COCc1nnc(-n2nnc(C#N)c2COC)s1 +Cc1cc(C)n(-c2cccc(NC(=O)c3c(C)cc(C)[nH]c3=O)c2)n1 +CC(=O)NC(C)C(=O)Nc1nnc(C(C)(C)c2ccccc2)s1 +Cc1nc(C)c(C(=O)NCc2cccc(Oc3ccccn3)c2)s1 +O=C(Cc1cccs1)N1CC(Oc2ccccn2)C2OCCCC21 +CCCN(CCC)C(=O)c1cc(N)n(-c2ccccc2)n1 +CSc1ccccc1C(=O)Nc1c(C)cccc1C +Cc1nn2cccnc2c1C(=O)NCC(C)c1cccs1 +O=C(OCc1ccc2c(c1)COC2)c1ccn2cncc2c1 +CC(CC(=O)Nc1nccn(C)c1=O)c1ccccc1F +CCc1ccc(C2CC(C)CCN2C(=O)c2ccc(=O)n(C)n2)o1 +CC(C)CC(CO)NC(=O)c1ccn2ccnc2c1 +CC(C(=O)Nc1ccccc1F)n1cnc2c1c(=O)n(C)c(=O)n2C +COC(=O)C(CNC(=O)c1scnc1C)Oc1ccc(F)cc1 +O=C(Nc1ccc(F)cc1F)N1CCC(CCO)CC1 +CC(C)COCCNC(=O)N1CCC(Oc2ccccc2)CC1 +Clc1cccc(CN2CCC(c3nc(-c4ccncc4)no3)C2)c1 +COc1ccc(Cc2noc(-c3cnc(C4CCCO4)s3)n2)cc1 +Cc1nnsc1C(=O)Nc1nc2c(C)cc(Cl)cc2s1 +O=C(Nc1cnn(Cc2cccc(F)c2)c1)c1cc2ccccn2n1 +Cn1nc2n(c1=O)CCN(CC(=O)N1CCCC3CCCCC31)C2 +CC1(c2cccnc2)OC(=O)N(CCc2ccccc2)C1(C)O +CCc1nc(CC(=O)Oc2cccc(Br)c2)cs1 +COc1ccc(C(=O)N2CCC(OC)CC2)c(O)c1 +COc1cccc(NC(=O)c2cnc3c(c2)c(=O)n(C)c(=O)n3C)c1 +CCC(=O)Nc1cccc(NC(=O)NCCC(=O)N2CCCC2)c1 +Fc1cc(CN2CCc3ccccc32)c2ncccc2c1 +CCCN(CC(=O)OC)c1cnc2ccccc2n1 +Cc1cc(C)n2nc(C(=O)NCc3nnc4n3CCCCC4)nc2n1 +Cn1cnnc1SCc1ccc(C(=O)Nc2ccccc2)cc1 +CCCn1nc(C)c(CNC(=O)c2sc(CC)nc2C)c1C +Cc1noc(C)c1S(=O)(=O)NC(c1ccccc1)c1nccn1C +Cc1ccc(-c2n[nH]cc2CNCC2(c3ccccc3F)CC2)o1 +COC1CCCC1OC(=O)c1ccc2c(c1)nnn2C +CN(C)C(=O)CNC(=O)CCSc1ccc(Br)cc1 +COc1ccc(NC(=O)c2cc(Cl)ccc2O)cn1 +CC(C)(NC(=O)C1CCCC1)c1nc2c(c(C(N)=O)n1)OCCO2 +CCC(C)NC(=O)CCNC(=O)NC(C)c1ccc2c(c1)CCCC2 +CCN(CCNC(=O)Nc1c(C)noc1C)C(=O)OC(C)(C)C +Cc1cc(C)nc(-n2nc(C)c(CC(N)=O)c2C)n1 +CCOc1ccc(-c2nc(CC(=O)NC3CCCC3)no2)cc1OC +CCn1ccc(C(=O)Nc2nnc(-c3ccc(C)cc3)o2)n1 +CN(Cc1ccco1)C(=O)COc1ccc(N2CCCC2=O)cc1 +CCn1nc(C(=O)NCC2CC2)cc1-c1ccc(OC)cc1OC +Cc1cc(=O)n(CC(=O)Nc2ccccc2)c(N)n1 +O=C(CCc1ccccn1)N1CCc2cccc(F)c21 +O=C(COCC1CCCO1)Nc1cc(Cl)ccc1-n1cncn1 +NS(=O)(=O)CCNC(=O)c1cc(-c2ccccc2)ccc1Cl +Cn1nccc1NC(=O)NCCCN1CCCc2ccccc21 +COC(=O)CNC(=O)C1(c2ccc(C)c(OC)c2)CC1 +CCOc1cccc(NC(=O)NC(C)CCCO)c1 +CC(C)c1nnc(CN2CCN(C(C)c3nc(C4CC4)no3)CC2)o1 +O=c1cc(CN2CC(c3cccnc3)C2)[nH]c2c(F)cccc12 +CCCCc1ccc(C(C)NCC(=O)N(C)C)cc1 +Cc1cc(N(C)C)nc(N2CCN(C(=O)c3ccccc3C)CC2)n1 +Fc1cc2c(cc1C(F)(F)F)CCNC2CC1CC1 +N#CC1(NC(=O)Cn2nc3ccccn3c2=O)CCCC1 +COC(=O)CC1CCN(C(=O)c2ccc(Cl)cc2)CC1 +Cc1cc(C2CCCN2c2ncnc3c2cnn3CCC#N)no1 +CCNS(=O)(=O)c1ccc(NC(=O)Cc2ccccc2C)cc1 +Cc1nnc(CCNC(=O)c2ccc(-c3cc[nH]n3)cc2)s1 +CCNC(=O)CN(CC)C(=O)c1csc(-c2ccc(C)cc2)n1 +C=C(C)COCCNC(=O)Nc1cc(F)ccc1OC +COc1ccccc1NC(=O)CC1NC(=O)c2ccccc2N=C1O +CC(c1ccccc1)n1ccc(NC(=O)N(C)CC2CCCC2O)n1 +O=C(Nc1cccc(N2CCOC2=O)c1)c1cn2cccnc2n1 +CC(=O)Nc1ccc(CC(=O)Nc2c(C)cc(C)cc2C)cc1 +CCCn1nc(C(=O)NCc2ccccn2)c2ccccc2c1=O +CCCCNC(=O)Cc1cc(-c2ccc(F)cc2)on1 +O=C(CNc1ccc(C(=O)N2CCCC2)cc1)Nc1ccccc1 +Cc1cc(C(=O)N(C)Cc2cnn(C)c2)c(C)n1Cc1ccco1 +COCCn1c(SCC#N)nnc1-c1ccncc1 +CCCOc1cc(C)ccc1CNC(=O)N1CCC(C(C)O)C1 +Cc1csc(CCNC(=O)c2nccc3cccc(N)c23)n1 +O=C(CN1CCCCC1=O)NCCCSc1ccc(Cl)cc1 +CCN1CCN(C(=O)c2cnc3nc(CC(C)C)nn3c2C)CC1 +CC(C)CCOC1CCN(Cc2nc3c(cnn3C)c(=O)[nH]2)CC1 +C=CCn1c(=O)n2nc(-c3ccco3)nc2c2c(C)c(C)sc21 +O=C(Nc1nnc(Cc2ccccc2)o1)c1ccc(Cl)cc1 +COCc1cc(C(=O)Nc2sc(C)c(C)c2C(N)=O)ccc1F +CCOC(=O)c1cnc(SCCN2CCOCC2)nc1N +Cc1csc(C(C#N)C(=O)c2ccc(-n3cncn3)cc2C)n1 +CCOC(=O)N1CCN(CC(=O)Nc2cc(C)on2)CC1 +FC(F)(F)c1cccc2c1CCNC2c1ncccn1 +CC(=O)NC(C(=O)Nc1cnc2c(cnn2C(C)C)c1)C(C)C +CCC(=O)Nc1cccc(NC(=O)N(C)Cc2cccc(C#N)c2)c1 +Cc1nn(C)c(C)c1CCC(=O)OCCn1c(=O)oc2ccccc21 +CC(C)(C)OC(=O)NC(C)(C)C(=O)N1CCOCC1 +CC(=O)N1CCN(CC(=O)c2ccc(Br)cc2)CC1 +Cc1nc(CC(=O)NCCCn2c(C)cccc2=O)cs1 +O=C(CCn1c(=O)oc2ccccc21)NC1CCCCCC1 +CCn1nc(C(C)C)cc1C(=O)NC(C)c1nc2ccccc2[nH]1 +OC(CN1CCN(c2ncnc3ccccc23)CC1)c1ccccc1 +OCc1nc2ccccc2n1Cc1cc(Cl)c2c(c1)OCO2 +O=C(Cc1cccs1)Oc1ccc(NC(=O)C2CC2)cc1 +CNc1ncc(C(=O)NC2CCCNC2=O)cc1Cl +O=C(NC1CCCCC1)N1CCN(C(=O)c2cccs2)CC1 +Fc1cc(Cl)c2c(c1)C(c1ccc[nH]1)NCC2 +O=C(Nc1nc2ccc(Cl)cc2s1)c1cccnc1 +CCC1CCCCN1C(=O)Cn1c(S(C)(=O)=O)nc2ccccc21 +CC1c2ccsc2CCN1S(=O)(=O)c1ccccc1 +Cc1nn(C)c2nc(N3CCN(C4CCCCC4O)CC3)sc12 +Cc1ccnn1CCC(=O)N1CC2CCC(C1)N(CC1CC1)C2=O +C#CCOCCC(=O)Nc1ccnn1-c1nc(C)cc(C)n1 +CC(O)CC(C)CNC(=O)Nc1ccc(NC(=O)C2CC2)cc1 +CC1COCCN1C(=O)c1cn(-c2ccccc2C(F)(F)F)nn1 +COc1ccc2cc(C(=O)N(C)c3ccc(OC)nc3)[nH]c2c1 +CC1CCCCC1NC(=O)CN1CCN(C(=O)CO)CC1 +CCc1ccc(NC(=O)COc2ccc(C#N)cc2OC)cc1 +COC(=O)c1nn(-c2ccc(F)cc2F)c(C)c1Cl +Cc1ccc(CCNC(=O)C2CCN(C(=O)OC(C)(C)C)C2)cc1 +CCC=CCC(=O)N1CCC(c2ccc3c(c2)OCO3)C(O)C1 +CCOC(=O)C12CC1CN(C(=O)OC(C)(C)C)C2 +CCOc1ccc(NC(=O)NCc2ccccn2)c(C(F)(F)F)c1 +Cn1ccnc1C(=O)c1ccc2c(c1)NC(=O)CO2 +Cc1cn2c(CC#N)c(-c3ccc(F)cc3)nc2s1 +COC(=O)c1c(NC(=O)c2ccc(OC)c(OC)c2)sc(C)c1C +COc1ccc(NC(=O)c2ccc(-n3ncc(C#N)c3N)cc2)cn1 +O=C(NCC(c1ccccc1)c1ccccc1)c1[nH]nc2c1COCC2 +CC(C)c1cc(C(=O)N2CCN(c3ccccc3F)CC2)cs1 +CC(C)N(Cc1ccccc1)C(=O)Cn1c(=O)n(C)c2ccccc21 +Cn1cc(-c2n[nH]c(-c3cnn(C)c3)c2Cl)cn1 +CN(Cc1cnccn1)Cc1ccc(C2CCCO2)s1 +COC(=O)C1(NC(=O)CCC(C)(C)C)CCCCC1 +CC(C)c1ccc(NC(=O)C2CC(=O)Nc3ncnn32)cc1 +COc1cc2cc(C(=O)c3ccccc3O)cnc2cc1O +O=C(NC1CCC1)C1CCC2(CN(Cc3cccnc3)C2)O1 +COCCOCC(=O)Nc1sc2c(c1C(N)=O)CCCCC2 +O=C(NCCCn1cccn1)c1c(Cl)ccc(Cl)c1Cl +CC(C)N1C(=O)C2(OCCO2)c2cccc(Cl)c21 +CC(C(=O)NCC(=O)N1CCc2sccc2C1)c1cccs1 +COCCOc1cc(NC(=O)c2ccoc2)ccc1OC +O=C(COCC(F)(F)F)NC1(c2ccc(Cl)cc2)CCC1 +Cc1ccc(OCC(=O)N(C)CC(=O)N2CCOCC2)c(C)c1 +NC(=O)Nc1cccc(C(=O)N2CCC3(CC2)OCCO3)c1 +Cc1ccc(NC(=O)c2nc3ccccc3n2C)cc1C +O=C(NCc1cn(-c2ccccc2)nc1-c1ccc(F)cc1)C1CC1 +Cc1c(C(=O)Nc2ccn(Cc3ccccc3)n2)[nH]c2c1C(=O)CCC2 +CCn1cc(NC(=O)c2ccc(C)cc2)c(C(N)=O)n1 +CCC(CCO)NC(=O)NC1CC(C)(C)Cc2oc(C)cc21 +C=CCn1nnc(C#N)c1CCOc1ccccc1 +CC(O)CN(C(=O)c1ccc2c(c1)OCO2)C(C)(C)CO +NC(=O)c1cccc(CN(Cc2cccs2)Cc2cccs2)c1 +COc1ccccc1CNC(=O)c1cc(C)nc(N)n1 +COc1ccc(F)cc1NC(=O)CN(C)C(=O)c1cccs1 +O=C(NCC1CCCC1)c1nnc2ccc(N3CCOCC3)cc2n1 +CCC(C)CN(C)C(=O)c1cn(C)nc1C(C)(C)C +Cc1ccccc1N(C(=O)c1ccncc1)C(C)C +COc1cc(NS(=O)(=O)c2ccccc2)c(OC)cc1N +CCC(C)NC(=O)Cn1cc(CO)c2cccc(C)c21 +CCC(=O)N1CCCCC1C(=O)N1CCN(C)c2ccc(F)cc21 +CCCC(C)NC(=O)c1ccc2c(c1)CCCN2S(=O)(=O)CC +Cc1ccc(NC(=O)c2ccc(O)c(Cl)c2)nc1 +CCC(C)NC(=O)CN1CCN(C(=O)Nc2ccncc2)CC1 +COC(=O)c1cccc(NC(=O)Cc2noc3ccccc23)c1 +O=C(c1ccsc1)N1CCC2(CC1)CC(Oc1ccccn1)CO2 +Cc1ccc(CC(=O)Nc2cc(N3CCCC3)ncn2)cc1 +COC1CCCOC12CCN(c1nnc(C3CCC3)o1)CC2 +O=C(Cn1ccnn1)NCC1(Cc2ccccc2)CCCC1 +Cc1scc(C(=O)N2CCN(Cc3ccccc3)CC2)c1C +CCCn1nccc1NC(=O)CNC(=O)c1ccccc1 +Cc1csc(C2CCCN(C(=O)c3ccnc(N(C)C)c3)C2)n1 +CCC(C)(C)NC(=O)c1oc2ccccc2c1COC +Cc1ccn2c(=NC(=O)C(C)CN(C)C(=O)OC(C)(C)C)[nH]nc2c1 +CCN1CC(CN(C)C(=O)c2ccco2)Oc2ccccc21 +Cc1occc1C(=O)NC(C)c1ccc2ccccc2c1 +COC(=O)c1ccc(Cn2nc(-c3ccco3)n(C3CC3)c2=O)o1 +CN(C)c1ccc(C(=O)OCC(=O)Nc2ccc(C(N)=O)cc2)cc1 +O=C(COc1nnc(-c2ccccc2)o1)N1CCCCCC1 +CCc1nc(C)ccc1OCC(=O)N(CC)CC +CCOc1ccccc1CNC(=O)NC1CCCCC1 +CC(=O)NC1CCCN(C(=O)c2ccc(Br)cn2)C1 +COc1ccccc1NC(=O)CCSc1nnc(C)o1 +Cc1cc(CN2C(=O)c3ccccc3S2(=O)=O)c2ccccc2n1 +Cn1cc(C(=O)NCCc2cccs2)ccc1=O +CC1(C(=O)Nc2ccc(-c3csnn3)cc2)CC1(Cl)Cl +COCCCNC(=O)CN(C)C(=O)c1ccccc1Br +CCCN(C)C(=O)Nc1ccc(C(=O)NCC(C)C)cc1C +CCc1noc(CC)c1CNC(=O)Nc1c(C)noc1C +O=C(CSc1c(-c2cccs2)[nH]c2ccccc12)NCCO +Nc1nc(C2CC2)ncc1C(=O)Nc1ccc(F)c(F)c1F +CN(C)c1sc2c(c1Br)COCC2 +CCC(Oc1ccc(Br)cc1)C(=O)Nc1cc(C)on1 +O=C(Nc1ccccc1)N1CCCC(c2nc3ccccc3[nH]2)C1 +COc1ccc(-c2nc3cc(F)cc(N)c3o2)cc1OC +COC(=O)C=C(C)c1cncc(-c2ccc(F)c(F)c2)c1 +CCC(C)n1ncc(C(=O)NCC(C)(C)C(=O)NC)c1C1CC1 +Cc1ccc(C(CNC(=O)CC2CCCCC2)N2CCOCC2)o1 +N#Cc1ccccc1NC(=O)C1CCN(c2ccccc2)CC1 +COc1cccc(C(=O)c2sc3nc(C)ccc3c2N)c1 +COc1ccc2cc(S(=O)(=O)Nc3ccncc3)ccc2c1 +Cc1ccc(C)n1CCCC(=O)N1CCn2c1nc1ccccc12 +Cc1nnc(SCCC(=O)NCc2ccc3c(c2)OCO3)n1N +COC(=O)c1cc(C#N)c(=O)n(CCCc2ccccc2)c1 +Cn1cnnc1C1CCCN1C(=O)c1ncn(-c2ccccc2)n1 +CC(=O)Nc1ccc(NC(=O)C(C)Nc2cccc(C)c2)cc1 +Cc1cc(NCc2cnc(-c3ccccn3)s2)c2ncccc2c1 +Cc1nc(C2CCCCCN2C(=O)Nc2cccc(C#N)c2)no1 +CCC(NC(=O)Cc1ccc(F)c(F)c1)c1ccc2c(c1)OCCO2 +Nc1ncccc1OCCCOCC(F)(F)F +COCC(=O)Nc1cccc(-c2cccc(OC)c2F)c1 +CS(=O)(=O)N1CCC(C(=O)NCCCc2ccco2)CC1 +COc1cccc(N2CCN(C(=O)NCCC(=O)NC(C)C)CC2)c1 +CCc1c(C(=O)Nc2ccc3c(c2)COC3)cnn1-c1ccc(C)cc1 +CCC(NS(=O)(=O)c1ccc(C)cc1)C(=O)NC(C)C +Cc1ccc(Cl)cc1NC(=O)COC(=O)c1nccnc1N +COCc1c(C(=O)NCc2nccs2)oc2ccccc12 +Cc1noc(C)c1CN(C)C(=O)CCc1cc(Cl)cs1 +CCN(CC)C(=O)CNC(=O)C1CCCCN1C(=O)OC(C)(C)C +CC(NS(=O)(=O)c1cccs1)C(=O)OCc1ccccn1 +O=C(Cc1cccs1)NC(CC(F)(F)F)c1ccc(F)cc1 +N#CC(NC(=O)c1cscn1)c1ccc(Cl)c(Cl)c1 +Cc1cc(C)n(CCCNC(=O)N2CC(C)c3ccccc32)n1 +Cc1cccc(-c2nc(CSc3nncs3)no2)c1 +COc1ccc(NC(=O)NCc2cnn3ccccc23)c(OC)c1 +COC(=O)CSc1nc(N)c(C#N)c(-c2cccs2)c1C#N +CCOc1ccc(C(C)N(C)C(=O)c2ccc(=O)n(C)n2)cc1 +O=C(NCC1CCOC1)c1ccc(N2CCNC2=O)cc1 +CN(Cc1ccc2nonc2c1)C(=O)C1CN(C)c2ccccc2O1 +Cc1cn2nc(N3CCC(C(=O)N4CCOCC4)CC3)sc2n1 +O=C(Nc1nccs1)NC1CCOC1c1ccc(Cl)c(F)c1 +Cc1ccsc1CNC(=O)CSc1cc(C#N)ccn1 +OC(CNC1CCSc2ccccc21)c1ccc2c(c1)OCO2 +COc1ccccc1NC(=O)Nc1cc(C)ns1 +COC(=O)CNC(=O)c1ccc(-c2ccc(C)cc2C)o1 +COC(=O)c1c(NC(=O)c2ccncc2)sc(C)c1C +CC(C)(C)n1cc(NC(=O)c2c[nH]c3cccc(F)c23)cn1 +COCC(O)CN(C)C(=O)c1ncoc1-c1ccccc1Cl +COc1ccc(CNC(=O)CCOc2ccc(F)cc2)cc1F +O=c1c2sccc2ncn1Cc1ccn(-c2ccccc2)n1 +CC(O)(CNC(=O)Nc1cccs1)c1cccs1 +Cc1nc(NCc2ccccc2)cc(-c2ccccn2)n1 +Cc1ccc(NC(=O)COc2ccc(N3CCCC3=O)cc2)c(O)c1 +CCOCc1ccccc1NC(=O)N1CCN(CCO)CC1 +Cc1ccc(C(=O)NCCCOc2ccc(F)cc2)c(=O)[nH]1 +Cc1ccc(C(=O)N2CCC3(CC2)OCCO3)c(O)c1C +CCNC(=O)COc1cccc(NC(=O)Cc2ccc(F)cc2F)c1 +Cc1ccc(F)cc1NC(=O)CCc1nc(-c2ccsc2)no1 +COC(=O)CCn1nc(C)c(CN2CCNC(=O)C2(C)C)c1C +COc1ccc(NC(=O)NCc2ccc(C)cc2N(C)C)cn1 +CN1CC(NC(=O)c2cccc(F)c2)CCC1=O +CC(C)CCC(C)NC(=O)CS(=O)(=O)c1nnc2ccccn12 +CC(=O)Nc1cc2c(c3c1CCC(=O)N3)NC(=O)CC2 +CN(c1ccc(NC(=O)NCc2cn[nH]c2)cc1F)C1CCCCC1 +CC(C)CNC(=O)CSc1ncnc2sc3c(c12)CCCC3 +O=C(Nc1cccc(F)c1)c1ccc(N2CCCOC2=O)cc1 +CNC(=O)c1nc(CC(=O)Nc2ccccc2)no1 +CCOC(=O)N(C)CC(=O)N1CCC(COc2ccccc2)CC1 +O=C(Cn1cc(-c2ccccc2)cn1)N1CCc2sccc2C1 +N#Cc1c(CCCNC(=O)C2CCCC2)nn(-c2ccccc2)c1N +N#CCOC(=O)c1c2c(nc3ccccc13)CCC2 +CCOC(=O)C1CCCN(C(=O)c2c(-c3ccccc3)noc2C)C1 +O=C(OCc1nc2ccccc2s1)c1cc2ccccc2[nH]c1=O +COCCn1ccc(NC(=O)NC2Cc3ccccc3C2)n1 +Cc1cc(NC(=O)CN2CCN(C(=O)OC(C)(C)C)CC2C)no1 +CC(=O)Nc1ccnn1Cc1cnn(-c2ccccc2)c1 +Cc1cc2occ(CC(=O)OCC(N)=O)c2cc1C +N#Cc1ccc(C(=O)NCC(O)(c2ccco2)C2CC2)cc1 +Cc1c(C(=O)N2CCCC2C(O)c2cccs2)oc2ccccc12 +Cc1onc(-c2ccccc2)c1C(=O)NCCNC(=O)C1CC1 +COC(=O)Cn1cc(C#N)c(=O)c2cc(C)cc(C)c21 +O=C(NCc1ccc2c(c1)OCCO2)c1cc2ccccc2c(=O)[nH]1 +CC(=O)c1sc(CNCCc2ccccc2)nc1C +CC1(C)CN(S(=O)(=O)c2ccc(C#N)c(Cl)c2)CCO1 +Cc1noc(C)c1Cc1nc(C(C)NC(=O)OC(C)(C)C)no1 +C=CCn1nnnc1NCc1c(F)cccc1Cl +CCCNC(=O)CCC(=O)Nc1cc2c(cc1Cl)OCCO2 +O=S(=O)(NCC#CCOc1ccccc1F)c1ccccc1 +N#Cc1cccc(CS(=O)(=O)N2CCC(CO)C2)c1 +O=C(Nc1cn[nH]c1)c1csc(-c2ccsc2)n1 +N#CCCN(CCN1CCOCC1)C(=O)c1ccccc1Cl +CCC(C)NC(=O)NCCNc1ncccc1C#N +COc1cc2oc(-c3ccc(O)cc3)cc(=O)c2c(O)c1OC +CCCn1nccc1NC(=O)C1CCOc2ccccc21 +CC(C)c1n[nH]c(C2CN(Cc3cn4ccsc4n3)CCO2)n1 +Cc1ccnc(NC(=O)CCNC(=O)c2ccc(Cl)cc2)c1 +Cc1cccnc1C(NC(=O)c1ccc(-n2ccnn2)cc1)C(C)C +Cc1noc2nc(-c3ccco3)cc(C(=O)OCCn3cncn3)c12 +Cc1nc2ccc(NC(C)c3cccnc3)cc2[nH]1 +Cc1cccc2c1CNCC2NC(=O)c1cccnc1 +Cc1c(C(=O)NCC(C)(C)O)cnn1-c1ccncc1 +Cc1csc(=O)n1CCC(=O)Oc1ccccc1F +CC(C)N(Cc1cccc(Cl)c1)C(=O)Nc1nncs1 +N#CCCCn1c(C(F)(F)F)nc2cc3c(cc21)OCO3 +CCOc1cc2c(cc1OC)CCNC2c1ccccc1 +CCOc1ccc(S(=O)(=O)NCCc2ccsc2)cc1F +CC(=O)C(C)CSc1nnc(-c2ccccc2C)o1 +CCN(CC)S(=O)(=O)CC(=O)NC1(c2ccccc2)CCC1 +COc1cc(OC)c(OC)cc1CNc1ccc(F)cn1 +CNS(=O)(=O)c1cccc(CNC(=O)c2ccnc(N(C)C)c2)c1 +Cc1cnc(C(=O)N2CC3(CCN(c4nccs4)C3)C2)cn1 +CC(C(=O)N1CCC(C(N)=O)CC1)N(C)Cc1ccc(C#N)cc1 +CCOCC1CCCN(C(=O)CCC(=O)c2ccc(C)cc2)C1 +COC(=O)C(NC(=O)c1ccc(Br)cc1)C(C)(C)C +CN(Cc1ccccc1NC(=O)C1CCC1)C(=O)OC(C)(C)C +CC(Sc1ccccn1)C(=O)NCC1(c2cccc(F)c2)CC1 +COc1cc(C(=O)N(C(C)C)C(C)C)ccc1Br +CC(C)n1cnc2cc(-c3ncc(N)nn3)ccc21 +CNC(=O)NC(C)(C)C(=O)Nc1cccc(C)c1C +COC(=O)C(O)(c1ccccc1)c1ccccc1O +Cc1csc(-n2nnc(C#N)c2C=Cc2ccccc2)n1 +CCn1nnc2cc(C(=O)NC(CC(C)C)C(=O)OC)ccc21 +COCC(C)N1CCN(C(=O)c2cn(C)nc2C)CC1 +CC(NC(=O)c1cc(N(C)C)ccc1F)c1ccccc1 +Cc1ccc2[nH]cc(NC(=O)NCCN3CCOCC3)c(=O)c2c1 +OCCC1CCCCN1c1nccc(C(F)(F)F)n1 +Cc1cccc(OCC(=O)N2CCc3cc(N)ccc32)c1C +CC(NC(=O)CCc1ccsc1)c1ccncc1 +CC1(C)CN(C(=O)Nc2ccc(F)cc2F)CCO1 +CCOC(=O)C1CCN(c2cc(C(C)=O)ccc2F)CC1 +Cc1cc(C)n(-c2ccc(C)c(Br)c2)n1 +O=c1[nH]c(CN2CCc3cncnc3C2)nc2ccccc12 +COc1ccc(NC(=O)C2CC2)cc1OC(F)F +CC1=CC(C)=NC(=O)C1CNC(=O)c1cccc(C)c1 +CCn1cnnc1CCn1ccnc1-c1cccc(-n2cccn2)c1 +Nc1cc(Cl)ccc1N1CCN(Cc2ccccc2)CC1 +FC(F)(F)c1csc(Sc2nnnn2CC2CCCO2)n1 +CCN(C(=O)COc1nncc2ccccc12)C1CCCCC1 +Cn1c(=NC(=O)C2COCCO2)[nH]c2cc(Cl)ccc21 +CN(C)C(=O)CN(C)C(=O)C1(c2cccc(Cl)c2)CC1 +CN(CCc1ccccc1)C(=O)NCCC(=O)N1CCCC1 +CCOC(=O)N1CCN(C(=O)Cc2c(F)cccc2F)CC1 +CN1C(=O)CCOc2ccc(S(=O)(=O)N(C)CCO)cc21 +CN(Cc1ccco1)S(=O)(=O)c1cc(Cl)ccc1C#N +Cc1cc(C(=O)NCC2CCCO2)c2cc(Br)ccc2n1 +CCOc1ccc(C(=O)Nc2ccc(C(C)=O)cc2)nn1 +Cc1cc(C)n(-c2ccc(NC(=O)NC3CCCC3)cn2)n1 +Cn1nccc1CNC(=O)NCc1ccccc1OC(F)(F)F +CC(NC(=O)CSc1ncn[nH]1)c1ccc(Cl)cc1Cl +COc1ccc(OC)c(C(O)CCC(=O)NC2CC2)c1 +Cc1cc(NC(=O)C2CCN(C(=O)CCc3ccco3)CC2)no1 +COc1ccc(-c2nn(C)c(N)c2-c2nc3ccccc3n2C)cc1 +COCC(=O)N1CCc2c(nc(-c3ccccc3)nc2N(C)C)C1 +CC(C)C(=O)NCCNC(=O)N(C)Cc1ccccc1C(F)(F)F +O=C(Nc1cccnc1)c1nn(-c2cccc(Cl)c2)ccc1=O +Cc1cccc(OCC2CCCN(C(=O)c3ccccc3C#N)C2)c1 +CC1CC1C(=O)N1CCCC(c2cc(C(F)F)n3ncnc3n2)C1 +CC(C)C1CCCN1C(=O)c1ccc(S(C)=O)cc1 +COc1ccc(CN(C)S(=O)(=O)c2cccs2)cc1OC +Cc1nc(CNc2cccc(S(=O)(=O)NC3CC3)c2C)no1 +O=C(Nc1cnn(-c2ncncc2N2CCOCC2)c1)C1CCCC1 +CC1CCCC(C)N1C(=O)CS(=O)(=O)c1nccn1C +COc1cccc(NC(=O)c2ccc3c(c2)OCCCO3)c1 +COc1ccc(CN(C)C(=O)C(C)c2ccsc2)cc1C +CS(=O)(=O)N1CC(C(=O)Nc2nc3ccc(Cl)cc3s2)C1 +CC(C)OC(=O)CNC(=O)NCc1ccc(F)cc1 +O=C(Nc1cccc(F)c1)C1CCN(C(=O)Cc2ccccc2)CC1 +O=C1COc2ccc(C(=O)Cc3ccc(Cl)cc3)cc2N1 +COc1ccc(Br)cc1C(CCO)C(C)C +CC(C)n1nccc1NC(=O)N(C)CCOc1ccccc1F +C=CCN(CC=C)Cc1c(O)c(=O)cc(C)n1C1CC1 +COc1ccc(OC)c(C(O)CNc2ncnc3sccc23)c1 +CCn1cc(N)cc1C(=O)Nc1ccccc1OC +Cc1n[nH]cc1NC(=O)Nc1ccn(-c2ncccc2Cl)n1 +CSc1ncccc1C(=O)NC(C)CCc1ccccc1 +O=C(Cc1ccc(N2CCCC2=O)cc1)OCc1cccc(F)c1F +CC1CCCN(C(=O)CCC(=O)N2CCOCC2)C1 +Cc1ccc(C(=O)N2CCCC2Cn2cccn2)cc1S(C)(=O)=O +CC(C(N)=O)n1nc(-c2ccc(F)cc2)ccc1=O +COc1ccc(CCNC(=O)c2ccnc(OC3CCC3)c2)cc1 +CCc1nsc(N2CCN(Cc3ccc(F)c(C)c3)CC2)n1 +C#Cc1cccc(NC(=O)c2ccnc(SCC)c2)c1 +NC(=O)c1ncc(Br)c2c(Br)cccc12 +CC(=O)Oc1ccc(C(=O)N2CCN(c3ccc(F)cc3)CC2)cc1 +CCN(C)c1ccccc1CNC(=O)c1ccccc1Cn1cncn1 +C#CCNS(=O)(=O)c1cccc(C(=O)Nc2nc(C)no2)c1 +CSc1nc(C2CC2)cc(C(=O)OC(C)C(=O)NC2CC2)c1C#N +CCCCC(=O)NCC#CCOc1ccc(C)nc1 +Cc1cc(COC(=O)c2ccc(N3CCCS3(=O)=O)cc2)on1 +N#CCOC(=O)C1COc2ccc(Cl)cc2C1 +CC(C)N1C(=O)c2ccccc2NC1(C)C(C)(C)C +Cn1c(=O)c(NCCc2ccc(Cl)cc2)nc2ccncc21 +C#Cc1cccc(NC(=O)N2CCN(c3cccc(OC)c3)CC2)c1 +CC(=O)NCCNC(=O)c1cccc(NC(=O)c2cccs2)c1 +Cc1noc(C)c1NC(=O)c1cc2c(=O)c3ccccc3oc2o1 +CC1CCC2(CC1)N=C(c1cccc(F)c1)C(=O)N2 +CC1COCCN1CC(=O)N(Cc1ccccc1)C(C)(C)C +COc1ccc(CNC(=O)Nc2cnn(C)c2)cn1 +CC(C)CCNC(=O)COc1cccc(Cl)c1 +N#Cc1ccc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)cc1 +Cc1cnn(C2CN(Cc3cccc(C(N)=O)c3)C2)c1 +CNC(=O)CN(c1cc(C)cc(C)c1)S(=O)(=O)c1ccccc1 +Cc1noc(CCCC(=O)N2CC=C(c3ccccc3Cl)CC2)n1 +CN(Cc1cccc(C#N)c1)C(=O)NCC1CN2CCCCC2CO1 +O=C(NCc1ccccc1)C1CCCN(c2cccnn2)C1 +Cc1nc2cc(NC(=O)c3cc(Br)cn3C)ccc2o1 +COc1ccc(C)cc1C(O)CCc1nccs1 +CCCCn1c(S(=O)(=O)Cc2ccc(F)cc2)nc(C)c1C +CC(C)(C)OC(=O)N1CCC(C(=O)NC2CCCC2C(N)=O)CC1 +CN(Cc1ccc2ccccc2c1)C(=O)CNC(=O)c1ccccc1 +Cc1csc(CCNCc2c[nH]nc2-c2cccs2)n1 +O=C1CCC(C(=O)N2CCCc3cc(F)ccc32)N1 +O=C(c1cccs1)N1CC2OCCN(c3ncccn3)C2C1 +CC(C)Oc1cccc(C(C)NC(=O)Nc2cnn(C)c2)c1 +CC(C)OC(=O)CCNC(=O)Nc1cnn(C)c1 +O=C(NCCc1ccccc1)NCc1cccc(Cn2cccn2)c1 +CC(O)CN1CCN(S(=O)(=O)c2cccc(F)c2)CC1 +CCN(CC(F)(F)F)S(=O)(=O)c1cc(N)ccc1C +O=C(CNc1cc(F)ccc1OC(F)F)NCC(F)(F)F +CCCc1cc(=O)[nH]c(SCc2ccc(C(=O)N(C)C)cc2)n1 +CCCS(=O)(=O)N(CCO)Cc1ccccc1 +CNc1cc(N2CCCC2CNc2ccc3nnnn3n2)ncn1 +Cc1ccn(CCC(=O)Nc2ccc(C(C)C)cc2)n1 +COc1ccc(OC)c(NC(=O)c2ccnc(-c3ccsc3)c2)c1 +Cc1nc2cc(=O)[nH]n2c(C)c1CNC(=O)c1cnc2ccccc2n1 +COC(=O)c1ccccc1OCC(=O)N(C(C)C)C(C)C +O=C(NC(c1ccccc1)c1ccncc1)c1ccncc1F +Cc1ccc(NC(=O)N2CCN(C(=O)c3cc[nH]n3)CC2)cc1Cl +CC(C)N(C)C(=O)NCc1cccc(OCC(=O)N(C)C)c1 +CCc1cccc(C)c1NC(=O)CSc1nnc(C2CC2)n1C +CC=CCn1c(SCCO)nc2c1c(=O)[nH]c(=O)n2C +COc1cc(OC)cc(C(=O)N2CC(C)OCC2C)c1 +COc1ccc(-c2n[nH]cc2-c2ccccc2)c(O)c1 +c1cc(-c2cc(N3CCOCC3)nc(-c3ccncc3)n2)ccn1 +COCCn1cc(NC(=O)N(C)C2CCCCCC2)cn1 +CN(CC1CC1)C(=O)CS(=O)(=O)c1cccc(Cl)c1 +CCn1c(C)cc(C(=O)OCC(=O)NCc2ccco2)c1C +Cc1ccc(C(C)NC(=O)NCC(F)(F)F)cc1 +CC(NC(=O)c1ccc(N2CCOC2=O)cc1)c1ccncc1 +CCC12CN3CC(CC)(CN(C1)C3c1cc3ccccc3[nH]1)C2O +CCC(C#N)CCC(=O)Nc1ccc2c(c1)OCO2 +O=C1COC2(CCN(C(=O)c3ccsc3)CC2)CN1 +O=C(NCCCOCC(F)(F)F)c1cc(F)cc(F)c1 +Cc1nc(C(C)N(C)Cc2nc(-c3ccco3)no2)c(C)s1 +CCOc1cccc(NC(C)C(=O)NC(C)C)c1 +COC(=O)c1ccc(CN(C)Cc2cc(F)cc3cccnc23)cc1 +Fc1cc(Br)ccc1OCc1nc(C2CC2)no1 +COc1ccnc(NC(=O)CNC(=O)c2ccc(C)c(C)c2)c1 +COC(=O)CCn1nnc(-c2ccc(C(C)C)cc2)n1 +CC(C)c1nccc(CN2CCN(c3ncnc4ccccc34)CC2)n1 +CCC(C)(C)NC(=O)c1cc(C(C)(C)C)nn1C +COC(=O)c1ccc(NCc2nc(-c3ccco3)no2)c(C)c1 +C=CCNC(=O)COc1ccc(Cl)cc1C(C)O +CCNC(=O)c1ccc(NC(=O)c2ccn(C)c(=O)c2)c(C)c1 +O=C1OC(NCCc2ccccc2)c2ccccc21 +COc1ccc(C(CC(=O)Oc2ccccc2F)NC(C)=O)cc1 +Cc1cnn(C2CN(Cc3ccc(C#N)cc3F)C2)c1 +CCOc1ccc(NC(=O)C2CC23CCCC3)c(C(N)=O)c1 +Cc1nc(NC(=O)C2(c3cc(-c4cccs4)on3)CC2)sc1C +COC(=O)c1sc(NC(=O)c2ccc(Cl)cc2Cl)nc1C +CC(=O)NCCNC(=O)Nc1ccc(Cl)cc1Br +O=C(CC1CCCC1)N1CCC2(CC1)OCCCC2O +CS(=O)(=O)NCCc1ccc(-c2csc(-c3ccoc3)n2)cc1 +CCCCNC(=O)c1nnn(-c2ccccc2F)c1C +CCOC(=O)CN(CC)C(=O)c1cc(F)c(Cl)cc1Cl +N#Cc1nccnc1-c1ccc(Cl)c(Cl)c1 +NC(=O)c1cccc(OC(=O)C2CC2c2ccco2)c1 +COc1cc(OC)c(C2=CCN(C(=O)c3ccc[nH]3)CC2)c(OC)c1 +CCOC(=O)c1c(NC(=O)CC)sc2c1CC(C)CC2 +Cc1nc(N)nc(COc2ccccc2C(C)C)c1C(N)=O +CCN(Cc1cccc2c1OCO2)C(=O)NCc1ccccn1 +Cn1cccc1C(=O)N1CCCC(c2nncn2Cc2ccccc2)C1 +CCC(=O)NCC(=O)NCC(=O)Nc1ccc(Cl)cc1 +Cc1n[nH]c(O)c1C(c1c(O)n[nH]c1C)c1cn(C)c2ccccc12 +CNC(=O)Nc1ccc(NC(=O)c2cccc(-c3ccoc3)c2)cc1 +Cc1ccc(-n2cc(C(=O)N3CCCCCC3)nn2)cc1 +CN(Cc1ccc(F)cc1)C(=O)Cn1nc(-c2cccs2)oc1=O +Cc1ccc(C)c(C(N)C(=O)NCc2cccnc2)c1 +COc1ccc(OC)c(NC(=O)c2c(F)c(F)c(F)c(F)c2F)c1 +COc1ccccc1CC(=O)NC(C)(C)c1noc(C(C)(C)C)n1 +Cc1ccc(OC(=O)Cn2nnc3ccccc3c2=O)cc1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)c1cc2ccccc2o1 +c1c[nH]c(-c2nnc(SCc3nc(-c4cccs4)no3)o2)c1 +Cc1ccccc1NC(=O)C(C)n1cnc2onc(C)c2c1=O +COc1ccccc1-n1nnc(C(=O)Nc2ccc(F)cc2F)c1N +COCCNc1nc2ccccc2n1CC(=O)C(C)(C)C +Cc1c(C(=O)N2CCCCC2)[nH]c2c1C(=O)CC(C)(C)C2 +CC(C)OCCCNc1ccc2nnc(C(F)(F)F)n2n1 +CCn1nc2c(cc1=O)CN(c1ncnc3sc(C)c(C)c13)CC2 +CNc1nc(CNC(=O)Nc2nnc(CC(C)C)s2)cs1 +O=C(NCCNC(=O)c1ccccn1)c1ccc(F)cc1 +CC(C)(C)OC(=O)N1CCOc2ccc(S(N)(=O)=O)cc21 +COc1ccc(C)cc1NCCC(O)c1ccccc1OC +Oc1ccc(NCc2ccc(F)c(F)c2)c(F)c1 +Cc1cc(NC(=O)c2cnc3ccccc3n2)n(CCC#N)n1 +Cn1cc(C2CCCN2C(=O)c2ccn(-c3ccccc3)n2)cn1 +O=C(Nc1ccccn1)C1CCCN(c2nc3cccnc3s2)C1 +O=C(NCc1ccccc1-c1cccnc1)c1ccn2ccsc12 +CN(Cc1ccc(-n2cncn2)cc1)Cc1nccs1 +CCCCc1noc(C2CCCN(C(=O)Cn3nc(C)cc3C)C2)n1 +Cn1cnnc1SCC(=O)Nc1ccc(Cl)cc1N +CN1CCc2c(C#N)c(N3CCN(CCO)CC3)n3cnnc3c2C1 +OC(c1ccncc1)c1ccc(Cl)c(Cl)c1 +CCCNC(=O)CCNC(=O)NCC(F)(F)F +CC1CC(c2ccc(F)cc2)CN1Cc1noc(-c2ccoc2)n1 +Cc1csc(CCC(O)c2cccc(Cl)c2)n1 +CC(C)(C)c1nnnn1CC(=O)NCCOc1cccc(F)c1 +O=C(OCc1ccccc1F)c1ccc(-n2cncn2)cc1 +O=C(NCC1CN2CCCCC2CO1)c1cccc(OC(F)F)c1 +Cc1nn(C)c(C)c1CN(C)c1nc2c(s1)c(C)nn2C +Cc1c(Cl)cccc1S(=O)(=O)Nc1cccc(NC(N)=O)c1 +Cc1ccc2ncc(C(=O)NC3CCOC3c3ccccc3)n2c1 +Cc1n[nH]c(C)c1CCC(=O)N(C)CCOc1ccccc1 +Nc1c(C(=O)NCc2ccccc2)nnn1Cc1ccc(F)cc1 +Cc1nc(-c2cc(C)n(CC(=O)NCC(F)(F)F)c2C)cs1 +O=C(CCC(=O)Nc1nccs1)NCC1CCOC1 +CCc1ccc(C(=O)CSc2nnc(C3CC3)n2CC)cc1 +N#Cc1ccc(CN2CCN(C(=O)CCn3cncn3)CC2)cc1 +O=C(NCCNC(=O)c1ccsc1)c1ccc(F)cc1 +CC(C)C(NC(=O)N(C)CC(O)C1CC1)c1nnc2n1CCC2 +COC(=O)c1cccn2nc(-c3ccc(OC)cc3)nc12 +CCN(Cc1ccccc1C)C(=O)NCCCOC +Cc1cccc(C(=O)NCCNC(=O)c2cccc(-n3cncn3)c2)c1 +C=CCN(Cc1ccccc1F)C(=O)c1scnc1C1CC1 +CSc1ccccc1C(=O)N(C)Cc1ccccc1 +CC(Oc1ccc(F)cc1Br)C(=O)NCCO +CCOC(=O)C1CC2CCC1CC21NC(=O)c2ccccc2N1 +COCCNC(=O)c1cc2occc2n1Cc1ccccc1Cl +CC(c1cccnc1)N(C)Cc1ncccc1C(F)(F)F +Cc1cc(CN(C)C(=O)CCOc2ccc(C(C)C)cc2)no1 +CN(CC(=O)NCc1cccnc1)C(=O)c1c[nH]c2ccccc12 +Cc1cccc(NC(=O)c2cnc(-c3ccco3)nc2N)n1 +COc1ccc(C(C)=O)cc1CC(=O)Nc1nc(C(C)=O)cs1 +CCN(CC(C)C)C(=O)Nc1ccc2nc(C)sc2c1 +OC1CCCN(c2nc(C(F)(F)F)nc3ccccc23)C1 +CCNC(=O)c1ccc2c(c1)nc1n2CCN(CC(C)C)C1 +COc1ncncc1NC(=O)N(C1CC1)C(C)c1ccco1 +CN(C)C(=O)COC1COC2(CCN(c3ncc(F)cn3)C2)C1 +Cc1ccc(NCc2ccc3c(c2)OCCCO3)cc1 +CCc1c(C)sc2nc(Cc3csc(C)n3)[nH]c(=O)c12 +N#Cc1c(NC(=O)c2ccccn2)sc2c1CCCCC2 +C#CCOc1ccc(CN2CCOC(C(N)=O)C2)cc1 +Cc1ncc(-c2nc(-c3cccs3)c(C)s2)c(N)n1 +Cc1c(C(=O)NC2(c3ccccc3)CCC2)oc2c1C(=O)CCC2 +COc1cccc(CNc2ccc3oc(C)nc3c2)c1 +CN(CC(O)C1CC1)C(=O)c1cccnc1N1CCCCC1 +Cc1ccc2c(c1)N(C(=O)c1ccnc(OC3CCC3)c1)CC(C)O2 +COCCn1nc(C)c(NCc2ccn(C)c2)c1C +COCCOc1cccc(CC(=O)N2CCOCC2C2CC2)c1 +CC(=O)NC(CC(=O)N1CCCCC1C)c1ccccc1 +COc1ccc(CCNC(=O)CNC(=O)c2ccccc2Cl)cc1 +COCC(C)NC(=O)NCC1(Sc2ccccc2)CC1 +C#CCCOC(=O)C1CCN(c2ccc(Cl)cn2)CC1 +C=CCn1c(CNC(=O)c2ccc(F)cc2)nc2ccccc21 +Cc1ccncc1NC(=O)CCCc1cc(F)ccc1F +COc1ccc2ccn(Cc3csc(C(C)OC)n3)c(=O)c2c1 +CCOC(=O)NCCC(=O)N1CCN(C(C)=O)CC1 +Cc1nc2ncnn2c(C)c1CCC(=O)Oc1cccc2ccccc12 +CC(=O)Nc1ccc(O)c(C(=O)NCCOc2cccc(F)c2)c1 +COc1ccc(S(=O)(=O)N(CC(F)F)c2nccs2)cc1 +CC(=O)Nc1ccc(OC(=O)Cc2ccccc2Cl)cc1 +CCN(CC)C(=O)c1snc(-c2ccncc2)c1N +CN(C(=O)c1cccc(S(=O)(=O)N(C)C)c1)C1CCCCC1 +COC(=O)CC(Cc1ccc(C)cc1)C(=O)OC +Cc1c(C(=O)N2c3ccccc3CC2C(N)=O)oc2ccc(F)cc12 +CCOCCCNC(=O)c1c(C)nn2cccnc12 +Cc1ccc(S(=O)(=O)Nc2cccc(S(C)=O)c2)c(C)c1 +C=CCNc1nnc(SCC(=O)N2CCCCC2)s1 +CCC(C)C(C)NC(=O)NCC(O)c1ccc(Cl)cc1 +COCCCNC(=O)c1cnn2c(-c3cccc(OC)c3)ccnc12 +O=C(NC1CCCC1)C1C2C=CC(C2)C1C(=O)N1CCOCC1 +O=S(=O)(NCc1ccoc1)c1cccc(Cl)c1Cl +COCC(=O)N1CC(OCc2ccccn2)C2OCCCC21 +CCS(=O)(=O)NCc1cccc(S(=O)(=O)NC)c1 +CCN(CC)C(=O)CCSc1nnc(-c2ccc(O)cc2)o1 +COc1ccc(C(=O)NCCc2nc(-c3cccs3)no2)cc1 +C=CCNC(=O)c1ccccc1NC(=O)COc1ccc(C)cc1C +NC(=O)C1(CNC(=O)c2cc(-c3ccccc3)cs2)CCOCC1 +COC(=O)c1ccccc1NC(=O)CSc1ncc2ccccn12 +Cc1cc(C)c2nnc(C(N)c3ccncc3)n2n1 +CCOC(=O)c1cnc(Nc2cccc(C(F)(F)F)c2)[nH]c1=O +Cc1ccc(NC(=O)c2ccc(CSc3ncn[nH]3)cc2)c(F)c1 +O=C(NCC(F)(F)F)c1ccc(-n2ccnc2)cc1 +CC(=O)N1CCCCC1c1ccc(-n2ccnc2C)nc1 +CCOC(=O)CC1=Nn2c(nnc2-c2cc(F)ccc2F)SC1 +c1ccc2nc(N3CCOCC3)c(N3CCOCC3)nc2c1 +CCCNC(=O)C(C)n1ncn2c(cc3occc32)c1=O +Cc1ccc(CC2Oc3ccc(O)cc3N(CCCO)C2=O)cc1 +CS(=O)(=O)c1ccc(NCc2ccc(Br)cc2)cc1 +COc1ccc(C)cc1S(=O)(=O)Nc1cccnc1 +CC(=O)NC(C)C(=O)NCC1CCC(C)(C)CC1 +CCOc1ccccc1CNc1cccc(C)c1N +Nc1ccc2nc(Sc3nc4ccc(N)cc4[nH]3)[nH]c2c1 +COc1ccc(F)c(NC(=O)C(C)NC(=O)C(C)(C)C)c1 +O=C(NCCc1ncc[nH]1)c1cccnc1SC(F)F +CN(Cc1ccsc1)C(=O)Cn1cc(CO)nn1 +Cc1ccc(-n2nnnc2CCc2ccccc2)cc1 +Clc1ccc2c(c1Cl)CCNC2c1cccnc1 +Cc1cccc(NC(=O)C(C)Sc2nnc(N)n2C(C)C)c1 +CCNC(=O)CCC(=O)N1CC2CCCN2c2ccccc21 +CC(C)C(C)NC(=O)CSc1nc(CC2CCCC2)n[nH]1 +Cc1cc(F)ccc1S(=O)(=O)N1CCCC(c2cnccn2)C1 +CNC(=O)c1cccc(Cn2cnc3ncccc3c2=O)c1 +COc1ccccc1S(=O)(=O)NCc1cnc(C)s1 +CC(=O)N1CCc2ccccc2C1CC(=O)N(C)CC(=O)NC(C)C +Cc1cccc(NC(=O)Cn2cc(Cl)cn2)c1C +CCCCS(=O)(=O)N1CCCc2cccc(O)c21 +Cc1cnn(CCC(=O)NCCOc2cccnc2)c1 +O=C(c1cccc(Cl)c1)N(CCO)C1CCCCC1 +CCN(C)C(C(=O)NCCc1nnc2n1CCC2)c1ccccc1 +Cc1cc(CC(=O)NCC(C)c2nc3ccccc3s2)n[nH]1 +Cc1csc(NC(=O)CN(C)Cc2nc3ccsc3c(=O)[nH]2)n1 +Cc1ccc(F)c(-c2nnc(-c3cccc(N)c3)o2)c1 +COc1ccc2c(c1)nc(C(C)O)n2-c1ncccc1C#N +COc1ccc(OCCC(=O)NCc2nc3ccccc3[nH]2)cc1 +Cc1nncn1-c1cccc(NC(=O)c2ccc3cc[nH]c3c2)c1 +COC(=O)c1sc(NC(=O)Cc2ccc(F)cc2)nc1C1CC1 +CNC(=O)CCc1ccc(NC(=O)COc2cccc(C)c2C)cc1 +C=CCCCN(C)C(=O)c1ccc(NC(=O)NC(C)C)cc1 +OC(CSc1ncc(C(F)(F)F)cc1Cl)C(F)(F)F +CCOC(=O)c1c(N)nc(C)c(Br)c1C +COc1ccccc1NC(=O)Cn1cnc2cc3c(cc21)OCCO3 +CCc1ccc(CNC(=O)NCc2cnn(C)c2)s1 +CCN(Cc1cccc(NC(=O)c2cc(OC)ccc2O)c1)C(C)=O +Cc1cccc(C(=O)Oc2ccc(N3CCOC3=O)cc2)n1 +O=C(NCc1ccccn1)C1CNc2ccccc2O1 +O=C(NCCN1CCOCC1)c1nnn(-c2ccccc2)n1 +COC(=O)C1(NS(=O)(=O)c2cn[nH]c2)CCC(C)CC1 +Cc1nc(-c2ccccc2)n(CC(=O)NCc2ccc(F)cc2)n1 +Cc1ccc(CN2CCCC(c3nnc4ccccn34)C2)s1 +COc1ccccc1C#CCNC(=O)CC1CCCC1 +O=C(NCC(=O)N1CCCC1)c1cc2c(s1)-c1ccccc1CC2 +CCCCN1CCN(C(=O)c2cn3cc(C)ccc3n2)CC1 +CCn1cnnc1CNC(=O)c1ccc(-n2ccnn2)cc1 +COc1ccc(C2CC(O)=Nc3c2cnn3C(C)C)cc1O +Fc1ccc(Cl)c2c1CCNC2c1cnccc1Cl +CCC(=O)N1CCc2c(C(=O)NCc3ccc(C)o3)cccc21 +Nc1cc(Cl)ccc1NC(=O)c1cccs1 +CCn1c(=O)n(CC(=O)N(C)Cc2ccccc2)c2ccccc21 +COc1ccc(CC(=O)Nc2nc(-c3cccnc3)cs2)cc1F +Cc1ccc(NC(=O)CSc2ccc3c(c2)OCCCO3)cc1 +CC1CCCCN1c1ncnc(Nc2ccc(F)c(F)c2)c1N +COc1ccc(-n2nc(C)c3nc(-c4nccn4C)[nH]c32)cc1 +CCC(NS(C)(=O)=O)c1ccccc1OCC(=O)N(C)C +CN(C)S(=O)(=O)c1ccc(COc2ccc(CO)cc2)o1 +CCC(C)NC(=O)NCc1ccc(-n2cccn2)cc1 +Cc1c(C(C)NC(=O)N(C)Cc2cnn(C)c2)oc2ccccc12 +COCC(O)CN(C)S(=O)(=O)c1cccc(F)c1 +CC(=O)Nc1ccc(NC(=O)c2cccc(C(=O)N(C)C)c2)cc1 +COc1ccccc1NC(=O)c1cnc2n(c1=O)CCS2 +COc1cc(OC)cc(C(=O)NCC(C)(OC)c2ccccc2F)c1 +CCCNc1ccc(C#N)cc1NC(=O)c1cscn1 +COc1ccc(CN(C)C(=O)NCCC(=O)N2CCCCCC2)cc1 +CNC(=O)NCCC(O)(c1ccc(C)o1)C(F)(F)F +O=S(=O)(NCCc1ccc(Cl)cc1)c1cccs1 +CN1CC(C(=O)NCCCC2CCCC2)CC1=O +Nn1c(SCC(=O)N2CCCCCC2)nnc1-c1ccncc1 +O=S(=O)(c1cccc(Br)c1)N1CCOC2CCCC21 +CC1(C)C(=O)NCCN1C(=O)c1ccc2c(c1)OCCO2 +COc1ccc(CCC(=O)N(C)Cc2ccccc2)cc1OC +Cc1cccc(CC(=O)NCCOc2ccc(S(C)(=O)=O)cc2)c1 +COc1ccccc1OCc1nc(N)nc(N(C)C)n1 +O=C(NCc1ccco1)c1csc(COc2cccc(F)c2)n1 +CCc1noc(C(C)Nc2ccn(Cc3ccccn3)n2)n1 +CCCCN(CC)C(=O)CN1CCN(C(=O)N(C)C)CC1 +Brc1cccc(OCC2OCCO2)c1 +CC(C)CC(=O)N1CCN(Cc2nc(-c3cccs3)no2)CC1 +Cc1ccc(CNC(=O)c2cc3c(s2)CCN3C(=O)C2CC2)o1 +COc1ccc(OC)c(C2CNCCN2C(=O)OC(C)(C)C)c1 +Nc1ccccc1CCC(=O)NCC1COCCO1 +CCC(CC)c1nnc(NC(=O)N2CCOC(C)(C)C2)s1 +CC(C#N)(NC(=O)CSc1ncc(-c2ccccc2)o1)C1CC1 +Cc1oc(C2CC2)cc1C(=O)NCC(C)n1cncn1 +O=C(c1cccs1)N1CCC(c2ccncc2)CC1 +O=C1CNC(=O)C(c2cccc(Br)c2)N1 +OCCOc1cccc(CN2CCN(c3ccccc3)CC2)c1 +CCN(CC)c1ncnc(Nc2ncccc2C)c1N +O=C(NC1CCCC1)c1cc(=O)c(OCc2ccccc2Cl)c[nH]1 +Cc1ccc(C(=O)Nc2ccc3nc(C4CCCO4)[nH]c3c2)cc1 +Cc1cc(C(=O)N(Cc2cnn(C)c2)C2CCCCC2)c(=O)[nH]c1C +Cc1ccnc(N2CCC(N(C)c3ccccc3)CC2)n1 +O=C(c1ccc[nH]c1=O)N1CCc2ccc(Cl)cc21 +COCCOC(=O)C(C)Sc1ccc(N)nc1 +CCC(NC(=O)c1cc[nH]c1C)C1CCOCC1 +CC(OCc1ccccc1)C(=O)Nc1nc2c(s1)CCC2 +Cc1nc(CN2CCN(C(=O)C(C)n3cncn3)CC2)cs1 +Cc1ccc(Cn2c(S(C)(=O)=O)nc3ccccc32)cc1 +CCNC(=O)CNC(=O)NCc1cccnc1OC +Cc1cccc2c(CC(=O)Nc3nc(CC(N)=O)cs3)c[nH]c12 +COC(=O)C1(C)CCN(C(=O)C2CC=CCC2)C1 +COCCCn1c(C(C)O)nc2cc(Cl)ccc21 +CN(C)c1ccccc1NC(=O)Cc1cccc(F)c1 +Cc1nn(C)c(C)c1OCC(=O)N1CCOCC1c1cccn1C +COc1ccccc1NC(=O)CSc1nnc(-c2ccncc2)o1 +COc1cccc(OCCN2CCNc3ccccc32)c1 +CC(NC(=O)NC(C)(C)C)C1CCCN(C(=O)C2(C)CCCC2)C1 +Cc1noc(-c2ccc(C(=O)N(C)CCC#N)cc2)n1 +COc1ccc2[nH]cc(C(=O)NCC3CCCCC3)c2n1 +CN(CC(=O)NC(C)(C)C)C(=O)C1CC(=O)Nc2cc(F)ccc21 +CC1CCN(C(=O)c2ccnc3c(Br)cccc23)CC1 +CCOC(=O)Nc1cccc(NCC(=O)NC2(C#N)CCCC2)c1C +Cc1c(N)cccc1NC(=O)C(C)OCCOC(C)C +CCOc1ccc2nc(Sc3ccc(N)cn3)[nH]c2c1 +CCc1nc(C2CCCN2Cc2nc(Cc3ccccc3)no2)no1 +CC(Cc1cccc(F)c1)C(=O)N=c1[nH]ncn1C +CC(Oc1ccc2ccccc2c1)C(=O)NCCCN1CCOCC1 +CC1(C)CN(Cc2cc(Cl)ccc2OCc2cccnc2)CCO1 +COc1cc(OC)c(NC(=O)NCc2cnc(C)s2)cc1F +CCc1noc(CSc2nnnn2-c2ccccc2)n1 +CCCCn1nc(C(=O)Oc2ccccc2F)ccc1=O +Nc1c(Nc2cccnc2)ncnc1OC1CCCCC1 +Cn1ncc2c(=O)n(CCC(=O)N3CCC4CCCCC4C3)cnc21 +NC(=O)c1ccc(C(=O)NCC2CCCOC2)cn1 +COc1ccccc1OCc1cc(=O)n2ccc(C)cc2n1 +COc1ccc(-c2nc3ccccn3c2CC#N)cc1OC +CCC(=O)Nc1ccc(C)c(NCC(=O)N2CCCC(C)C2)c1 +CC(C)(C)c1csc(NC(=O)Cn2nc3ccccn3c2=O)n1 +O=C(Cc1cnn(-c2ccccc2)n1)NC1CCOCC1 +Cn1ccnc1C(NC(=O)Cc1ccccn1)C1CC1 +Cc1csc(-c2ccc(C(=O)Nc3nc[nH]n3)cc2)n1 +O=C(NCc1cccs1)NCC1(c2ccccc2)CCOCC1 +O=C(Cn1nnc(-c2ccccc2-n2cnnn2)n1)N1CCCCC1 +CC(C)C(NCC(=O)N1CC(=O)Nc2ccccc21)c1ccccc1 +O=C(NCc1cc2n(n1)CCCN(C(=O)C1CCC1)C2)C1CCCC1 +CNC(=O)NCC1CCC(CNC(=O)NC)CC1 +CCOc1cccc(SC(C)C(=O)N2CCNCC2)c1 +CC(C)(C)OC(=O)N1CCC(OCC2CC2)CC1 +CC(OCCCNC(=O)C1CNC(=O)N1)c1ccccc1 +CC(C)OCC(=O)N1CCN(CC(O)c2ccccc2)CC1 +COc1ccccc1OCCN(C)C(=O)c1cc2ccccc2[nH]1 +COc1ccc(C(O)C(=O)NC2CC2)cc1Cl +O=C1CN(C(=O)Cc2cccc(C(F)(F)F)c2)CCN1 +COc1ccc(CCNC(=O)NC2CCN(C(=O)C(C)C)CC2)cc1 +COCCNC(=O)N1CCC(Oc2nc3ccccc3s2)CC1 +CC(=O)Nc1ccc(CNC(=O)c2nn(-c3ccccc3)nc2C)cc1 +CCN(CC(=O)OC)C(=O)Cc1ccc(Cl)cc1 +Cc1ccc(C(=O)NCc2cn3ccccc3n2)c(O)c1 +O=C(NCc1ccc(OC(F)F)cc1)c1cc(-c2cccnc2)on1 +Cc1cccc(CS(=O)(=O)c2nc(C)cs2)c1 +O=C(c1cnn2cccnc12)N1CCC(CCN2CCOCC2)CC1 +O=C1c2ccccc2C(c2c[nH]c3ccccc23)N1CC1CCCO1 +C=CCN(CC=C)C(=O)CSc1ncccc1N +CCOc1ccc(F)c(C(=O)NC(C)CC(=O)c2ccco2)c1F +Cc1noc(C)c1S(=O)(=O)N(C)C(C)c1ccccc1Cl +NC(=O)c1ccc(=O)n(Cc2csc(-c3ccccc3F)n2)n1 +CN1CCOC(CNc2nccc(C(F)(F)F)n2)C1 +Cc1ccc2ncc(CN3CCC(Oc4ccccc4)CC3)n2c1 +CCOCCNC(=O)N(CC)Cc1ccccc1C +COc1ccc2[nH]cc(CCNC(=O)c3c(C)noc3C)c2c1 +NC(=O)c1cccc(CNC(=O)Nc2nc(C3CC3)cs2)c1 +c1nc(C2CCC2)sc1CN1CCCCC1CN1CCOCC1 +Cc1n[nH]c(Nc2cc(C(F)(F)F)ccc2Cl)nc1=O +CC(=O)c1c(C)nc(C)nc1SCc1cn2ccsc2n1 +Cc1ccc(Sc2ncnc(NCC3CCCO3)c2N)cc1 +CC(NC(=O)Nc1ccc(C#N)c(Cl)c1)c1ccccn1 +CCN(c1nc2c(s1)c(C)nn2C)C1CCOCC1 +COCc1cccc(C(=O)Nc2cc(Cl)ccc2C(N)=O)c1 +COCCNC(=O)CNC(=O)c1cc(Cl)c[nH]1 +CNC(=O)NCC(=O)NCc1ccc(F)c(Cl)c1 +COc1cc(OC)c2c(c1OC)C(=O)NCC21CCCCC1 +CCOC(=O)N1CCC(OC(=O)CC(C)(C)C)CC1 +CNC(=O)Cn1c(-c2ccccc2)cc2ccccc21 +CCCCc1cnc2c(c1SC)c(=O)n(C)c(=O)n2C +COc1cccc(CN2CCN(C(=O)c3cc(C)n[nH]3)CC2=O)c1 +CCS(=O)(=O)N(C)c1ccc(C(=O)NC(C)C)cc1 +Cc1ccc(C)c(OCc2c(C#N)nnn2CC(O)CO)c1 +COC(=O)C1CCN(C(=O)c2cc(Cl)cc(Cl)c2)CC1 +CNC(=O)Cc1ccc(NC(=O)NCC(C)N2CCOCC2)cc1 +CNC(=O)c1cc(-c2ccc(OC)cc2OC)nc(N)n1 +N#CCCN(CCC#N)C(=O)c1cccc(N2CCNC2=O)c1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)Nc3cc(C)ccc3C)ccc21 +O=C(Cc1ccc[nH]1)NCC(=O)Nc1ccccc1 +NC(=O)c1csc(NC(=O)c2cccc(Cl)c2)n1 +O=C(COc1cccc2cccnc12)Nc1ccc(O)cc1 +Cc1ccc(C(=O)N2CCOCC2c2ncon2)cc1Cl +O=C(c1ccc(-n2cncn2)nc1)N1CCCC2(CCCCCC2)C1 +Cc1ccc(F)cc1NC(=O)Cn1nc2c(cc1=O)CCCC2 +CN1C(=O)CCc2cc(C(=O)Nc3cccc(C(F)(F)F)n3)ccc21 +CCC(C)N(CCO)S(=O)(=O)c1c(C)cc(C)cc1C +COC(=O)C(C)CN(Cc1cccs1)C1CC1 +CC(=O)NC(C)C(=O)Nc1ccc(SC2CCCC2)cc1 +COC(=O)CNC(=O)C(C)Sc1ccc(C(C)C)cc1 +CCOC(=O)c1cn[nH]c1NCc1ccccc1C +Cc1nn(C)c(C)c1CC(=O)N1CCC(COc2ccccc2)CC1 +CN1CC(NC(=O)c2cc(Br)c[nH]2)CCC1=O +CC1=C(C(N)=O)C(c2c(F)cccc2Cl)n2ncnc2N1 +COc1cc2c(cc1NC(=O)c1c(C)nn(C)c1C)oc1ccccc12 +Cc1cccc(NC(=O)CSc2nnc(-c3cnccn3)n2C)c1 +C=CCn1nnc(NC(=O)c2cc(Cl)cc(Cl)c2OC)n1 +O=S(=O)(NCc1ccc(Cn2cccn2)cc1)N1CCCCCC1 +CC(=O)NCC1CCN(c2ccnc(-c3ccccc3)n2)CC1 +N#Cc1cnn(C(=O)COCCOc2ccccc2)c1N +O=C(NCc1ccc(F)cc1)c1cccc2cc[nH]c12 +Cc1ccc(NC(=O)CSc2nc(C)cs2)cc1 +N#CCOc1cccc(CC(=O)NCC(O)c2ccc(Cl)cc2)c1 +FC(F)(F)c1nnc(N2CCC(n3cccn3)CC2)s1 +O=c1n(Cc2noc(-c3ccc(F)cc3)n2)nnn1-c1ccccc1 +O=C(NCc1nncn1C1CC1)Nc1cccc(-c2cccs2)c1 +CCCc1nc2cc(C)cnc2n1Cc1ccccc1C#N +Cc1cc(C(=O)N(C)CC(=O)Nc2c(C)cccc2C)c(C)o1 +CC(=O)c1ccc(N2CCN(Cc3cnc(C)s3)CC2)c(F)c1 +O=C(NCC1(CO)CCOCC1)c1cccc(OCC(F)F)n1 +COC(=O)c1ccc(C(=O)N(C)Cc2ccc(F)c(F)c2)s1 +O=C(NC1CC=CC1)NC1CCCN(c2ccccc2F)C1=O +CCC(C)n1cccc(C(N)c2cc(C)ccc2OC)c1=O +CCC(CC)NC(=O)C1Cc2cc(Cl)ccc2O1 +CCN1CCN(C(=O)c2cc(C)nc(N(C)C)n2)CC1 +CCOC(CC)C(=O)NCC1Cc2ccccc2O1 +COc1ccccc1C(C#N)NC(=O)Cc1cccs1 +O=C(CCCSc1ccccc1)N1CCC2(CC1)OCCO2 +CCOC(=O)N1CCN(C(=O)c2csc(-n3cccc3)n2)CC1 +CCOc1ccc(N2CCn3c2nc2c3c(=O)[nH]c(=O)n2C)cc1 +COc1ccc2cccc(NC(=O)c3ccco3)c2n1 +CNC(=O)CCOc1ccc(Br)cc1 +O=C(Nc1nc2c(s1)C(=O)CCC2)c1ccc(Cl)cc1F +CC(C)CCNC(=O)C1CCN(c2ccc(F)cc2)C1=O +O=C(COc1cccc(O)c1)Nc1ccccc1F +COCCCN1CCN(C(=O)c2cc(CC(C)C)nn2C)CC1 +O=C(NCc1ccncc1)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCC(C)NC(=O)COc1ccccc1Br +O=C(Nc1cccc2cn[nH]c12)c1cc2ccccc2c(=O)[nH]1 +Cc1oc(-c2ccc(Cl)cc2)nc1C(=O)N1CCOC2CCCC21 +Cn1ncnc1-c1cccn(Cc2c(Cl)cccc2Cl)c1=O +CC(C)C(O)CC(=O)Nc1ccc(N2CCCCC2)cc1C(N)=O +COc1cc(CC(=O)Nc2ccnc(N(C)C)n2)ccc1C +O=S(=O)(c1ccc2c(c1)OCCO2)N1CCC(O)C1 +CC(C)c1nnc(NC(=O)Cn2nc3c(cc2=O)CCCCC3)s1 +Nc1cccc2c1N(CC(=O)Nc1ccccc1F)CCO2 +CCOCCNC(=O)c1ccc2c(c1)NC(=O)CN2C +Cc1ccc(NC(=O)c2cc(Br)cn2C)cc1 +CC(O)CN1CCN(C(C)C(=O)NCCC2=CCCCC2)CC1C +CCC(CO)NC(=O)NC(C)c1ccc(-n2cncn2)cc1 +CN(CCOc1ccccc1)C(=O)Nc1ccc2c(c1)COC2 +CSc1ccc(CNc2ccccc2CC(=O)N(C)C)cc1 +Cc1oc(C)c(C(=O)NCc2csc(-c3ccccc3)n2)c1C +Cc1cccc(Cl)c1OCC(=O)N1CCN(C(=O)C2CC2)CC1 +COCC(=O)N1CCCN(c2ccccc2C#N)CC1 +COc1cc(C(=O)COC(=O)c2ccccc2)cc(OC)c1O +CC1CC(N2CCCN(S(=O)(=O)c3ccccc3)CC2)C(=O)O1 +CN(Cc1ccco1)c1nncc(-c2cc3ccccc3o2)n1 +CCS(=O)(=O)N1CCCC1c1ccccc1Br +CC(NC(=O)c1coc2nc3ccccc3nc12)c1ccccc1 +CCc1noc(C2CCCN(C(=O)c3ccc(C)s3)C2)n1 +COC(=O)c1c(C)n(-c2ccccc2)c2ccc(O)cc12 +CCCNC(=O)Cn1c(=O)n(Cc2cccs2)c2ncccc21 +c1ccc(Cc2n[nH]c(CCn3nnc(-c4ccccc4)n3)n2)cc1 +CCN(CCO)C(=O)C(Sc1ccccc1)c1ccccc1 +CS(=O)(=O)c1cccc(NC(=O)CC23CC4CC(CC(C4)C2)C3)c1 +O=C(COc1ccc(F)cc1Br)NCC(F)(F)F +CC(OC(=O)C1CCCN1C(=O)c1ccco1)c1cccc(F)c1 +Cc1noc(C)c1S(=O)(=O)NCCC(O)c1ccccc1 +CC(=O)c1ccccc1-c1ccc2ncnc(NCCO)c2c1 +COc1ccc(NC(=O)Cc2cc(C)ccc2OC)cc1 +Cc1cc(NC(=O)c2cccc(F)c2)ccc1-n1cnnn1 +COCCNC(=O)N1CC=C(c2c[nH]c3ccc(OC)cc23)CC1 +COc1ccc(NC(=O)NCCC(=O)Nc2ccccc2)cc1 +Cc1nn(CCNC(=O)Cn2cc(C)c(=O)[nH]c2=O)c(C)c1Cl +Cc1cc2c(=O)n(Cc3nc(-c4ccoc4)no3)cnc2s1 +O=C(Cc1nc2cc(F)ccc2c(=O)[nH]1)N(CC(F)(F)F)C1CC1 +Cc1ccccc1CC(=O)OCC(=O)Nc1ccc(F)cc1F +CCc1noc(C2CCN(C(=O)COc3c(C)cccc3C)CC2)n1 +CCc1csc(C2CCCN(C(=O)c3ccc[nH]3)C2)n1 +N#CCCN(c1ccccc1)c1ccc(F)cc1N +O=C(CNC(=O)C1CC1)Nc1cnn(CC(F)(F)F)c1 +O=C(Cc1n[nH]c(=O)c2ccccc12)N(CCO)Cc1ccccc1 +CN(CCc1ccccc1)C(=O)c1ccccc1Br +CC(C)CNC(=O)NCC(=O)Nc1ccc(Cl)cc1 +Oc1cccc(-c2cc(C3CCN(Cc4cncnc4)C3)ccn2)c1 +COc1cc(CN(c2ccc(C)cc2)S(C)(=O)=O)cc(OC)c1 +CC1CCCC(CNC(=O)C2CCCN2C(=O)c2ccco2)C1 +Cc1ccc(CC(=O)N2CCC(C(=O)N(C)C)CC2)cn1 +CCOc1ccc(S(=O)(=O)N(C)C)cc1C(C)(C)C +O=C(c1cn2cccnc2n1)N(Cc1ccco1)Cc1ccco1 +CCNC(=O)C(N)c1ccc(OC(F)F)c(O)c1 +O=C(Nc1ccccc1Cl)C1CCCN(C(=O)C2CC2)C1 +Cc1cc(C)cc(N2CC(C(=O)NC(C)C)CC2=O)c1 +CCS(=O)c1scc(-c2ccc(Cl)cc2)c1C#N +Cc1cc(C)n(CC2CCCCN2C(=O)c2cnccn2)n1 +CC(=O)Nc1ccc(C(=O)Nc2ccc3c(c2)OCCCO3)cc1 +O=C(NCCc1ccc(Cl)cc1)c1n[nH]c2c1CCCC2 +CCN(Cc1nonc1C)C(=O)c1ccc(C(F)(F)F)cc1 +N#Cc1ccc(OC(=O)c2ccc(-n3cncn3)nc2)cc1 +CC(=O)NCCNC(=O)Nc1ccccc1OC1CCCC1 +CCOC(=O)CN(C(=O)c1cc(-c2ccc(C)cc2)no1)C1CC1 +O=C(OCCn1cncn1)C1CCCN(C(=O)Nc2ccccc2)C1 +CCS(=O)(=O)N1CCN(c2c(C)n[nH]c2C)CC1 +O=C(NC1CC(=O)N(C2CC2)C1)c1ccc(-c2cscn2)cc1 +CCCNC(=O)Cn1nnc(CO)c1-c1ccncc1 +CC(=O)Nc1cc(NS(=O)(=O)c2ccc(F)cc2)ccc1C +CCCC1CN(C(=O)CCc2nnc(C3CCCC3)o2)CCO1 +CCC(CC)C(=O)Nc1ccc(C(=O)N2CCC(C)CC2)cc1 +O=C(Nc1ccc(Cl)cc1)N1CCCC1CO +O=C(c1c(Cl)cccc1Cl)N1CCOCC1 +CC(=O)Nc1ccc(S(=O)(=O)Oc2cccc3cccnc23)cc1 +Nc1nc2n(n1)C(c1ccco1)CC(c1ccccc1Cl)N2 +CC(C)OC(C)C(=O)NCc1cc2n(n1)CCN(C(=O)N(C)C)C2 +Cc1cc(C(=O)N2CCc3cc(F)ccc3C2)nn1-c1ccccc1 +COc1cc(-c2nnc3ccc(N)cn23)ccc1C +CCCN(C)C(=O)Nc1ccc(C(=O)NCc2ccccc2)cc1 +COc1cc(Cl)c(C)cc1NCCC(=O)NC1CC1 +CC1(C)CN(Cc2cc(=O)oc3cc4c(cc23)CCC4)CCO1 +COCCN(Cc1ccoc1)S(=O)(=O)c1cccc(Cl)c1 +Cc1cnn(CCC(=O)N(C)c2cccc3ccccc23)c1 +CCCC(=O)N(CCN1CCOCC1)c1nc2ccc(C)cc2s1 +Cc1cccc(CCNCc2ccc(C#N)cc2)c1 +O=C(OC1CCCC1)c1ccccc1S(=O)(=O)N1CCCCC1 +COc1ccc(C(=O)Nc2ccccc2-n2cnnn2)c(OC)c1 +Cc1ccc(NC(=O)CN(C)C(=O)CC2C=CCC2)cc1 +CC(C)OC(=O)CSc1nnc2c3ccccc3n(C)c2n1 +Cc1cc(C(=O)Cn2cnc(C#N)n2)c(C)n1CC1CCCO1 +O=C(CSc1cccc2cccnc12)Nc1ccc(F)cc1 +N#CC1CN(Cc2cn(-c3ccccc3)nc2-c2cccnc2)CCO1 +COc1ccc(OC)c(NC(=O)C(C)OC(=O)C2CC=CCC2)c1 +CC(C)(C)NC(=O)CNC(=O)CNC(=O)OC(C)(C)C +O=C1NCC(C(=O)Nc2ccc(Oc3cccc(F)c3)nc2)N1 +Cc1ccc(OCC(=O)Nc2ccc(CCC(=O)N(C)C)cc2)cc1 +Cc1ccnc(NC(=O)CN(C)Cc2nc(N)c3ccccc3n2)c1 +COc1ccccc1OCC#CCNC(=O)c1ccc(F)c(F)c1 +Cc1ncsc1COC(=O)CCc1cc(Cl)cs1 +COc1ncnc2c1CN(Cc1csc(NC(C)=O)n1)CC2 +Cc1ccc(-n2ccc3nc(N4CCOCC4)ncc3c2=O)cc1 +COCCNc1ncnc2c1oc1nc(CC(C)C)c3c(c12)CCC3 +CC(=O)Nc1cccc(NS(=O)(=O)c2ccc(C)cc2Cl)c1 +Cc1c[nH]cc1C(=O)N1CCN(Cc2nc(C(C)C)no2)CC1 +CCOC(=O)N1CCC(OC(=O)CCc2ccc(F)cc2)CC1 +Cc1cnc2c(c1NCCc1ccccc1)c(=O)n(C)c(=O)n2C +Cc1c(Br)cccc1CS(=O)c1ncccc1Cl +CCc1ccc(NS(=O)(=O)c2cc(C(=O)OC)n(C)c2)cc1 +CC(C(=O)N1CCN(c2ccccc2)CC1)N1Cc2ccccc2C1=O +CN(C(=O)OC(C)(C)C)C1CCCN(c2ncc(F)cn2)C1 +CCc1ccc(C2CC(C(F)(F)F)n3ncc(C#N)c3N2)s1 +N#Cc1ccccc1NC1C(=O)Nc2ccc(F)cc21 +CCCN(CC#Cc1ccccc1)C(=O)C1CCCN(C(N)=O)C1 +CN(C)c1ccc(NC(=O)Cc2ccsc2)nc1 +CC(C)c1nccn1Cc1ccccc1Br +CNS(=O)(=O)c1cc(C(=O)NCc2cccnc2)ccc1OC +COC(=O)CCCCNC(=O)NC1c2ccccc2CC1O +CCCc1nc(-c2cc3ccccc3[nH]c2=O)no1 +O=C1CCN(Cc2cccc(-n3cccn3)c2)CCN1 +O=C(c1cc(Br)c[nH]1)N(Cc1ccccc1)C1CC1 +CC(C)Oc1ncc(C(F)(F)F)cc1Br +O=C(CSc1ccncc1)N1CCC(CO)CC1 +CCc1ccc(CCNC(=O)NC(C)Cn2cncn2)cc1 +CNC(=O)c1ccc(CN(C)C(=O)CCOc2ccccc2)cc1 +CCCC(C)C(=O)N1CCN(S(=O)(=O)c2ccccc2F)CC1 +CCc1ccccc1NC(=O)Cc1ccc(N2CCCC2=O)cc1 +Cc1ccc(NC(=O)Nc2c(C)nc3ncnn3c2O)cc1 +COc1ccc(C(=O)N2CCc3c(nc(C)[nH]c3=O)C2)c2ccccc12 +OCCc1nnc(COc2ccc3c(c2)CCCC3)o1 +CNC(=O)c1cccc(NC(=O)C(C)Oc2cccc(F)c2)c1 +CN(CC1CC1)C(=O)c1ccc(Cn2cccn2)cc1 +CCC(C)NC(=O)NCc1ccc(COC)cc1 +CCc1noc(C)c1C(=O)Nc1nc(-c2cccs2)cs1 +COc1ccccc1CN(C(=O)c1c(O)cccc1F)C1CC1 +Cc1nnc(CN(C)Cc2cc(Cl)c3c(c2)OCCO3)n1C +CC(OC(=O)c1cn(C)nc1C(C)(C)C)c1nccs1 +Cc1cc(C)c(NCc2ccncc2Cl)c(C)c1 +CCNC(=O)CNC(=O)C1CC1c1ccccc1OC(F)(F)F +Cn1c(N)nnc1SCc1cccc(C(N)=O)c1 +COCC(C)NS(=O)(=O)c1cccc(C(C)=O)c1 +Cc1ccccc1OCC(=O)Nc1ccc2c(c1)nc(C1CC1)n2C +Cc1ccc(C(=O)CCN2CCN(c3ccccc3)CC2)cc1N +N#Cc1cccc(S(=O)(=O)NCc2ccc(Cl)cc2Cl)c1 +O=C(Cn1ccccc1=O)NCc1cccc2cccnc12 +CCOc1ccc(-n2cc(C)c(C)c(C#N)c2=O)cc1 +Cc1ncc(Br)c(Cc2ccccc2)n1 +Cc1ccc(CCCC(=O)N2CCCS2(=O)=O)cc1 +CCn1ccc(C(=O)Nc2nc(C)c(C(C)=O)s2)n1 +O=C(OCc1nnc(-c2ccccc2)o1)C1CCCO1 +CC(=O)N1CCCN(S(=O)(=O)c2ccc(C)c3ncccc23)CC1 +OCCN(Cc1cccnc1)Cc1cccn1-c1ccccc1Cl +O=S(=O)(c1cccc(-c2nnco2)c1)N1CCOCC1 +Cc1cc(C)n2nc(C(=O)Nc3cccc4cccnc34)nc2n1 +CC(C)Oc1cnc(S(N)(=O)=O)c(OC2CC2)c1 +CC(C)c1nc(CC(=O)N(C)Cc2nnc3n2CCC3)cs1 +Cc1ccc(NC(=O)c2cc(-c3ccncc3)[nH]n2)c(Cl)c1 +C=CCN1C(=O)C(O)(CC(=O)c2ccccc2)c2cc(Cl)ccc21 +O=C(CCCNC(=O)c1ccsc1)NCc1cccc(Cl)c1 +COc1ccc(C(=O)N2CCCN(C(=O)OC(C)(C)C)CC2)cc1 +CNC(=O)C1CCN(C(=O)CC2CC3CCC2C3)CC1 +CCOCC(=O)N1CCC(c2nc3ccccc3[nH]2)CC1 +CC(=O)NCC(=O)NC1CCN(c2ccc(C(C)(C)C)cc2)CC1 +CN(CCN1CCOCC1)CCS(=O)c1ccccc1 +O=C(NCc1ncc[nH]1)Nc1nnc(Cc2ccc(F)cc2)s1 +Cc1cc(C)n2nc(C(=O)Nc3cccc4ccccc34)nc2n1 +CCCNC(=O)CS(=O)(=O)c1ccccc1Cl +C=CCN1CC2(CCC1=O)CCN(C(=O)C1(C)CCCCO1)CC2 +CC(NCC1CCCO1)C(=O)c1ccc2c(c1)NCC(C)(C)O2 +COCCn1cc(NC2CCN(c3ccccc3)CC2)cn1 +COc1ccc2cnn(-c3ccccc3)c(=O)c2c1OC +CCOC(C(=O)NCC(C)(C)C(N)=O)c1ccccc1 +Cc1ccc(S(=O)(=O)NCC(C)(C)NS(C)(=O)=O)c(C)c1 +C=CCSc1ccccc1NC(=O)c1cccnc1 +Cn1cc(CNC(=O)NCc2ccccc2Cl)cn1 +COc1ccc(C(C)(C)C)cc1-c1cc(N)nc(=O)[nH]1 +COC(=O)c1cccn1C1CCN(C(=O)c2ccsc2)CC1 +NC(=O)C1Cc2ccccc2CN1Cc1coc(-c2cccs2)n1 +CCCCC(NC(N)=O)C(=O)NC1(c2ccccc2)CCC1 +COc1ccc(NC(C)=O)c(NCC(=O)NC2CCCCC2)c1 +Cc1nn2ncc(C(=O)NCCCC(=O)Nc3ccccc3)c2[nH]1 +CCCC1CCN(S(=O)(=O)c2cnc(N)nc2)CC1 +COC(=O)c1ccc(NC(=O)C2CCN(C(=O)O)CC2)cc1 +CNC(=O)COC(=O)C(C)Sc1ccc(Cl)cc1 +O=C(c1cccc(OCc2ccccc2)c1)N1Cc2cncnc2C1 +Cn1cc(CNC(=O)c2cc(S(N)(=O)=O)ccc2Cl)cn1 +Cc1ccc(C(C)N(C)c2ncnc3c2cnn3C)s1 +CCCN(CCC)C(=O)C(C)Sc1nc2ccccc2c(=O)n1C +CCC(C)N(Cc1ccccc1)C(=O)NCc1ccccn1 +O=C(NCCc1ccccc1F)c1ccc[nH]c1=O +CC(C1CC1)N(C(=O)Cn1c2c(sc1=O)CCCCC2)C1CC1 +CCOCC1CCN(C(=O)c2cnn(C(C)CC)c2C2CC2)C1 +CCC(=O)Nc1ccc(S(=O)(=O)c2ccc(NC(C)=O)cc2)cc1 +N#CCCn1ncc2c(N3CCNC(=O)C3)ncnc21 +CC(NC(=O)NCC1CCOC1)c1ccc2c(c1)CCC(=O)N2 +CN(C)c1ccc(C(=O)NCC(=O)Nc2cccc(F)c2)cc1 +O=C1CCCN1c1ccc(OCc2cc(-c3ccco3)on2)cc1 +Cc1nc(N)cc(-c2ccc(OCC(C)C)cc2)n1 +Cc1noc(C)c1CN1CCc2[nH]nc(-c3ccc(F)cc3)c2CC1 +CCCCN(C)C(=O)c1cnc(N2CCCCCC2)nc1N +Cc1cccc(C)c1NC(=O)Cn1c(C)nc2ccccc21 +Cc1nn(Cc2cccc(Cl)c2)c(C)c1NC(=O)c1ccncc1 +O=C1C2CC(CN2Cc2cccnc2)N1c1cccc(Cl)c1 +Cc1ccsc1CNC(=O)CSc1nnnn1-c1ccccc1 +O=C(c1cccnc1)N1CCCC(CCc2c(F)cccc2F)C1 +Cc1nc(C)c(CCNC(=O)NC(C)C2COc3ccccc32)s1 +CC(=O)c1cccc(NC(=O)COC(=O)c2occc2C)c1 +COCC(=O)N1CCC(c2nc3ccccc3o2)CC1 +Cc1nc(-c2ccc(NC3CCOCC3)cc2)cs1 +Cc1ccsc1-c1nccn1CCc1ccco1 +O=C(NCC(=O)N1CCc2ncccc2C1)c1cccc(Cl)c1 +COC(=O)c1ccc(CSc2nnc(N)n2C2CC2)cc1F +Cc1ccccc1-c1nc(CN(C)Cc2nonc2C)c(C)o1 +Nn1c(SCC(=O)N2CCCCC2)nnc1-c1ccc(F)cc1 +COc1ccccc1NC(=O)C1CCCN1C(=O)Cc1cccs1 +OC(c1ccccc1Cl)C1NCCc2ccccc21 +O=C(Oc1c(Cl)cc(Cl)c2cccnc12)N1CCCC1 +CCCn1c(=O)c(-c2ccc(C(=O)N(C)C)cc2)nc2ccccc21 +CNc1nc(-c2ccc(C)n(CCC(C)C)c2=O)cs1 +COCCn1cc(NC(=O)N(C)CC2CC2)ccc1=O +CCOc1ccc(CNC(=O)N2CCOCC2C2CC2)cc1C +O=C1CCC2(CCCN(C(=O)c3ccsc3)CC2)N1 +O=C(NCc1nc(-c2cc3ccccc3o2)no1)OCc1ccccc1 +CC(C)C1NCCc2cc(O)c(OC(F)(F)F)cc21 +CCC1c2ccsc2CCN1C(=O)c1ccccc1COC +O=C(NCc1csc(C2CC2)n1)NC1CC(=O)N(C2CC2)C1 +COc1ccccc1NCC(=O)N(C)Cc1ccc(SC)cc1 +O=C(Nc1cccnc1)NC1CCc2c(F)cccc21 +COc1ncccc1N(C)C(=O)C(C)OC1CCCC(C)C1 +N#CCC(=O)Nc1ccnn1Cc1ccc(OC(F)(F)F)cc1 +Cc1ccc(CC(=O)Nc2c(C)cccc2Cl)cn1 +CC(C)c1noc(CCC(=O)N2CCN(C)CC2c2ccccc2)n1 +COc1ccc(NC(C)=O)cc1NC(=O)NCCC1CC2CCC1C2 +CN(CC(F)(F)F)C(=O)Cn1cnc2c(cnn2C)c1=O +Cc1nc(-c2ccccc2)sc1CN1Cc2ncccc2C1=O +O=C(Nc1ccccc1Cl)N(CCO)C1CCCC1 +COC(=O)c1ccc(NC(=O)NCc2ncoc2C)cc1Cl +O=C(c1ccc(F)cc1)N1CCC(S(=O)(=O)c2ccccc2)C1 +CC(NC(=O)NCCCN1CCOCC1)c1ccc2ccccc2c1 +CCCn1nc(-c2ccc(C)c(C)c2)cc(C(C)=O)c1=O +CCS(=O)(=O)N1CCN(c2cccc(C(F)(F)F)c2)CC1 +CCc1ccc(C(NC(=O)c2cc(C(N)=O)cs2)C(C)C)cc1 +CC(=O)N1CCCC1C1NCCc2ccc(O)c(F)c21 +CC(NC(=O)c1nccnc1N)c1ccc(Cl)cc1 +COc1ccc(NC(=O)c2cc(O)c(OC)cn2)cc1 +O=C(Nc1ccccc1Cl)c1c[nH]c2c(Cl)cccc2c1=O +CCC(NC(=O)Cn1cccn1)C12CC3CC(CC(C3)C1)C2 +CCN(C)S(=O)(=O)NC(c1ccccn1)c1ccccc1OC +CCN1C(=O)COc2ccc(C(=O)NC(C)(C)C)cc21 +c1ccn2c(C3CCN(c4ncnc5sccc45)CC3)nnc2c1 +Cc1cc(OC(=O)C2CCCN2C(=O)C2CC2)ccc1Cl +CN(C)C(=O)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1 +CCNC(=O)c1cccc(NC(=O)N(CCO)Cc2ccccc2)c1 +CC(Oc1cccc(C#N)c1)C(=O)N1CCOCC1 +CNC(=O)c1ccc(NC(=O)NC2C3CCC(C3)C2CO)cc1 +O=C(Cc1ccon1)NCc1ccc(S(=O)(=O)N2CCCC2)cc1 +O=C(NCCc1ccc2ccccc2n1)c1ccnc(-n2ccnc2)c1 +Cc1ccn2c(=O)c(NC(=O)c3ccccc3C)cnc2c1 +O=C1CCCN1CCCNc1nc(-c2ccccc2)no1 +O=C(CC1CCCC1)NCc1nnnn1-c1ccc(F)c(F)c1 +CN(C)c1ccc(C(=O)N2CC(c3nc(-c4ccccn4)no3)C2)cc1 +CC(C)c1noc(CNC(=O)NCc2ccco2)n1 +COCCn1c(C(=O)NC(C)C)nc2ccccc2c1=O +CCn1cc(-c2cncn2CC(C)n2nc(C)cc2C)cn1 +COC(=O)c1ccccc1NS(=O)(=O)c1ccc(C(N)=O)cc1 +Cc1noc(C)c1S(=O)(=O)NCc1cc(F)cc2c1OCOC2 +CN(CCCCC#N)C(C(N)=O)c1cccc(F)c1 +Cn1c(SCC(=O)c2ccc(Cl)cc2)nnc1C1CC1 +Fc1ccccc1CN(CCc1ccncc1)C1CC1 +COC(C)C(=O)NCC1CCN(c2ccc(Cl)cc2)C1 +CC(C)S(=O)(=O)c1cccc(C(=O)Nc2ccccc2Cl)c1 +O=C(NCCc1cccc(O)c1)c1cccc(-n2cccn2)n1 +COc1ccc(C(=O)C(C#N)c2nc(-c3ccccc3)cs2)cc1 +CC(C(N)=O)N(C)C(=O)N(c1ccccc1)c1ccccc1 +CC(Cc1ccco1)NC(=O)Cn1c(=O)c(=O)n(C)c2ncccc21 +Cc1ccsc1C(=O)OC(C)c1nc2ccccc2c(=O)[nH]1 +O=C(COC(=O)CN1C(=O)COc2ccccc21)NCC1CCCO1 +COc1cccc(N2CCC(CNc3cc(C)nc4ncnn34)C2)c1 +Cc1nc(-c2c[nH]c(C(=O)Nc3cccc(C(N)=O)c3C)c2)cs1 +CC(=O)N1C=Cc2ccccc2C1CC(=O)OC(C)C +Cc1cc(C(=O)NCC(C)C)ccc1NC(=O)CNC(N)=O +COc1ccc(C(O)CCNc2ccc(C#N)cc2)cc1OC +COc1ccc(CNc2nc(-c3ccccc3)nn2C(C)=O)cc1 +CN1CC(c2nc3ccccc3n2CCN2CCOCC2)CC1=O +CC(=O)NCc1nc2cccnc2n1Cc1ccccc1 +CC(NC(=O)c1ccn(C)c(=O)c1)c1nc(-c2ccc(F)cc2)no1 +CC(C)OCCCNC(=O)c1cc(F)ccc1-n1cnnn1 +Cc1cc(C(=O)N2CCCC2c2ccsc2)no1 +O=C(NCc1cc[nH]n1)N1CCCC1c1ccsc1 +COc1ccccc1NCC(=O)Nc1ccc(C(=O)N(C)C)cc1 +O=C(NCc1ccccn1)NCC(O)c1ccc(Cl)cc1Cl +CCC(=O)Nc1cc(S(=O)(=O)NC2CCCC2)ccc1OC +NC(=O)Nc1cccc(CNC(=O)CCOc2ccc(Cl)cc2)c1 +CCCn1nc(C(=O)NCCC(C)C)ccc1=O +CCCCNC(=O)N1CCCN(C(=O)CC)CC1 +CCC(=O)Nc1c(C(=O)N(CC)CC)oc2ccccc12 +COCC12CCCOC1CCN(C(=O)c1cccc3c1OCCO3)C2 +Cc1cc(C(=O)N(CC(C)C)CC(C)C)c2c(C)nn(C)c2n1 +COc1cc(NCCc2scnc2C)ncn1 +Cc1ncsc1C1Nc2ccccc2C(=O)N1CCO +COc1ccc(S(=O)(=O)NCc2ccccn2)cc1 +Cn1nnnc1SCC(=O)NCCN1CCc2ccccc21 +CC(C)n1ncc2cc(NC(=O)c3cccc(-n4cnnn4)c3)cnc21 +CNC(=O)c1ccc(=O)n(CC(=O)NC(C)(C)C)c1 +COc1ccc(C(=O)NCc2ccccc2F)c(OC)c1OC +CCNC(=O)N1CCN(Cc2nc(N)nc(N(C)C)n2)CC1 +O=C(Cc1csc(-c2cccc(F)c2)n1)NCC1CCCO1 +O=C(COc1cccc2c1CCC2=O)NCc1ccccc1Cl +Fc1ccc(-c2cc3nc4c(c(N5CCOCC5)n3n2)CCC4)cc1 +FC(F)(F)c1nc2cc(Br)cnc2o1 +O=C(CC1CCCCC1)NCCNC(=O)N1CCOCC1C1CC1 +CCCn1c(=O)c2c(nc3n(C(C)C)c(C)cn23)n(C)c1=O +COc1cc(OC)nc(Sc2ccccc2CO)n1 +CC(=O)Nc1ccccc1OCC(=O)Nc1ccc(C#N)c(Cl)c1 +COc1ccc(-c2cc(Cn3cnc(C#N)n3)on2)cc1 +CCCn1nc(C(=O)Nc2ccc(C#N)cc2)ccc1=O +O=C(OCCOc1ccccc1F)c1ncoc1-c1ccco1 +Cc1cc(C(=O)N2CCN(Cc3ccccn3)CC2)c(C)n1C(C)C +CCOc1ccc(C(C)=O)cc1NC(=O)c1ccccc1C +COc1ccccc1S(=O)(=O)N1CCOC(c2ccccc2)C1 +CCc1cc(-c2cnn(C)c(=O)c2C#N)ccc1OC +Cn1nnnc1COc1cccc(C(=O)N2CCCC2)c1 +CCc1cccc(C)c1NC(=O)CCNC(=O)c1ccc(Cl)cc1 +CCc1cccc(NC(=O)CNC(=O)CC(C)(C)C)c1 +CC(Oc1ccccc1)C(=O)Nc1cnn(C2CCOCC2)c1 +Fc1cnc(N2CCC3OCCN(Cc4ccncc4)C3CC2)nc1 +CCCCNC(=O)Cn1c(C)cc2ccccc2c1=O +COCCCCc1nc2ccc(C(C)C)cc2c(=O)[nH]1 +O=C(Nc1ccc(Cl)cc1)c1c(-n2cnnn2)sc2c1CCC2 +CC(=O)Nc1ccc(C(C)C)cc1Br +Cn1nc(CNC(=O)Nc2cccs2)cc1-c1ccccn1 +O=C(NCc1ccco1)c1ccc(N2CCCCC2)cc1 +N#CC1(NC(=O)CCC(=O)c2ccc3c(c2)OCCO3)CCCCC1 +COCc1nc2c(s1)CN(C(=O)c1ccccc1OC)CC2 +COC(=O)C1=C(C)Nc2nnnn2C1c1ccccn1 +COc1cc(N)c(Cl)cc1-c1n[nH]c(-c2ccc(O)cc2)n1 +COc1ccc2nc(-c3ccnc(S(C)(=O)=O)c3)[nH]c(=O)c2c1 +O=C1COc2ccc(C(O)CN3CCOCC3)cc2N1 +COc1ccccc1NCc1cc(C(N)=O)ccc1F +CC(=O)NC(C)C(=O)OC(C(=O)Nc1cc(C)on1)c1ccccc1 +COc1cc(C)ccc1OCC(=O)N1CCCCCC1 +Cc1cc(F)ccc1CCNC(=O)NCC1CC1 +Cn1ccnc1COc1ccc2ccc(O)cc2c1 +O=C(CNC(=O)c1ccc2cc[nH]c2c1)NCCN1CCOCC1 +CCC(C)NC(=O)CN1CCN(C(=O)c2c(C)nn(C)c2C)CC1 +COc1ccc(CN(C)c2cc(C)nc3ccnn23)c2cccnc12 +COCc1nc(COc2cccc(C)c2)sc1C(C)=O +CC1(C)Cc2cccc(OCCNC(=O)Cn3cccnc3=O)c2O1 +Cc1c(C(=O)NC(C)CO)nnn1-c1ccc(F)cc1 +O=C(NCCc1ccsc1)Nc1cccc(F)c1F +O=C(NCCNC(=O)C1CC1)c1cccnc1Sc1ccccc1 +Cc1cc(OC(=O)C2CC(=O)N(C(C)C)C2)ccc1Cl +CCN(CC)C(=O)CN(C)C(C)c1nc2ccccc2c(=O)[nH]1 +CSc1ccccc1NC(=O)CSc1nnc(C)n1N +COc1cccc(CNC(=O)CSc2nccn2C)c1 +CCc1nc(CN2CCN(c3ccc(C#N)cc3)C(=O)C2)no1 +Cc1nc(CNc2cc(F)ccc2-n2cccn2)cs1 +COc1ccc(-c2cc(C(=O)N(C)C)nc(N)n2)cc1 +CCN(C(=O)c1ccc(-n2ccnn2)cc1)c1ccc(C#N)cc1 +CCN(CC)S(=O)(=O)c1ccc(C)c(C(=O)N2CCC(O)C2)c1 +O=C1COCC1CCc1cccc(Br)c1 +O=C(Nc1ccc(-n2cccn2)cc1)Nc1ccccc1Cl +COc1cccc(OC)c1C(=O)Nc1ccc(-c2cnco2)cc1 +CCN1CCOC(CCNC(=O)Cc2ccc(F)c(F)c2F)C1 +CC(C)S(=O)(=O)NCC(C)(C)c1ccccc1 +COc1ccc(OC)c(C(=O)NC(C)C(C)C)c1 +CSc1ccccc1C(=O)Nc1ccc2nc(C)sc2c1 +O=C(NC1CCCC1)C1CCN(c2ncnc3[nH]cnc23)CC1 +COc1ccc(OC)c(-c2cc(C(=O)NCc3ccsc3)no2)c1 +CCC(C)C(=O)N1CCCC(C(=O)N2CCC(C)CC2C)C1 +CC(CCc1cccn1C)NC(=O)N1CCOCC1C1CC1 +COCC(NC(=O)Cc1csc(-c2cccs2)n1)C(N)=O +CCC1CCCC(NC(=O)NCCc2ccc(C)nc2)C1 +CCCC1CN(C(=O)C2CCCc3[nH]ncc32)CCO1 +CC(=O)N1CCC2(CC1)OC(=O)C(C)=C2C(=O)NCCC(C)C +CC(C)Cc1ncc2c(n1)CN(C(=O)c1csc(C(C)C)n1)C2 +Cc1nc(-c2ccncc2)sc1C(=O)NCC1CCCO1 +COc1ccc(CCCC(=O)N2CC3CCC2CN(C(C)=O)C3)cc1 +COc1cccc(CNc2ccc3c(c2)CCC3)c1OC +NC(=O)NCCNC(=O)CCCc1cc(F)ccc1F +CSc1cc(C(=O)N2CCC(C)c3ccccc32)ccn1 +CCCCCC(=O)N1CCC(c2nc(-c3ccncc3)cs2)CC1 +CC(c1cccc(Cl)c1)N(C)C(=O)NCc1ccccn1 +Cc1ccc(C)c(S(=O)(=O)Cc2noc(-c3cccs3)n2)c1 +Cc1cccc(NC(=O)CSc2nnnn2-c2ccc(O)cc2)c1 +CCOC(=O)C1CCC(=O)N1c1ccc(F)c(Cl)c1 +CS(=O)(=O)Nc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1 +CCCC1CCC(NC(=O)NCC(=O)NC2CC2)CC1 +CC(CNC(=O)c1cn(C)nc1C(C)(C)C)N1CCOCC1C +Nc1c(-c2cccs2)nc2ccc(C(F)(F)F)cn12 +CCCc1c(C(=O)N2CCC(C(=O)N(C)C)CC2)[nH]c(C)c1C(C)=O +COc1cccc(C(=O)Nc2ccc(N3CCCC3)nc2)c1O +O=C(c1cccnc1)N1CCN(Cc2cccc3cc[nH]c23)CC1 +COc1cc(OC)c(NC(=O)c2ccccc2)cc1F +N#CCC1CCCc2c1cnn2Cc1cccc(Cl)c1 +Cc1cccc(N2CCN(C(=O)C(C)C)CC2)c1C +O=C1OC(c2ccccc2)N=C1Cc1ccc2c(c1)OCO2 +O=C(Cn1ccccc1=O)N=c1[nH]nc2ccccn12 +Cc1cccc(C)c1NC(=O)Cc1nc(CO)cs1 +O=C(NC1(c2ncon2)CCOCC1)c1cccc(Cl)c1F +Cn1ccnc1COc1ccc(NC(=O)CCc2ccsc2)cc1 +Cc1ccccc1C1CN(Cc2ccc(CO)o2)C(C)CO1 +CNC(=O)C1CCCN(C(=O)CCCOc2ccccc2)C1 +O=C(CCn1nnc2ccccc2c1=O)OCC1CC1 +CC(CNC(=O)c1ccc[nH]c1=O)CN1CCCC1=O +CCc1cccc(OCC(=O)N(C)c2ccc(O)cc2)c1 +COCc1ccccc1C(=O)Nc1cc2c(cc1Cl)NC(=O)CO2 +CC(=O)NCCNC(=O)Cn1cc(C(F)(F)F)ccc1=O +CCc1nc(CC(=O)Nc2cccc(COC)c2)cs1 +CC(O)CNC(=O)CCc1nc2sc3c(c2c(=O)[nH]1)CCC(C)C3 +CCCCC1C(=O)N(C)CCN1Cc1ccsc1 +CCC(C)Oc1ccc(C(=O)Nc2sc(C)c(C)c2C(N)=O)cc1 +CCOc1ccc(C(C)NC(=O)NCC(=O)NC2CC2)cc1 +c1ccc(Cc2noc(-c3cccc4cn[nH]c34)n2)cc1 +Cc1csc(CNC(=O)N(C)CC2COc3ccccc3O2)n1 +Cc1ccc2c(CC(=O)Oc3cccc(C(N)=O)c3)coc2c1 +N#Cc1ccc(OS(=O)(=O)c2ccccc2C#N)cc1 +Cn1nnc(NCc2ccc(-c3ccc(Cl)cc3)o2)n1 +COC(=O)c1ccc(C2CC2)c(Br)c1 +CCOc1ccc(S(=O)(=O)N(CC(N)=O)c2ccccc2)cc1 +COc1ccc(NC(C)=O)cc1S(=O)(=O)NCc1ccco1 +O=C(Cc1ccc(-n2cnnn2)cc1)Nc1ccc(F)c(F)c1F +Cc1cccnc1NC(=O)c1cc(S(=O)(=O)N2CCCC2)cn1C +O=C(c1ncoc1C1CCCO1)N1CC2(CCCC2)c2ccccc21 +CC1(C)Cc2cc(CNc3ccc4[nH]nc(C(N)=O)c4c3)ccc2O1 +CCc1onc(C)c1NC(=O)NCc1cccc(Cn2cccn2)c1 +CNC(=O)c1ccc(CSc2nnc(-c3sccc3C)o2)cc1 +O=C(CSc1nnnn1C1CC1)Nc1ccc2ccccc2c1 +COc1ccnc(NC(=O)c2ccccc2Cl)c1 +Nc1ccnc(C(=O)NCc2ccc(F)cc2F)c1 +CCc1cccc(NC(=O)Cn2cnc3sc(C)cc3c2=O)c1 +Cc1ccc(CNC(=O)c2ccc(F)cc2F)n1C +Cc1nnc(C)c2c(C)n(C(C)c3ccccc3)c(C)c12 +CC1CCc2ccccc2N1C(=O)c1cscn1 +N#CCn1c(-c2ccc(F)cc2)nc2cc(N)ccc21 +Cc1cc(N)c2oc(C(=O)Nc3ccccn3)cc(=O)c2c1 +COCc1noc(-c2ccc(OCC(F)F)nc2)n1 +NC(=O)c1cccc(CSc2nnnn2C2CC2)c1 +N#Cc1ncn(CC(=O)Nc2cccc3ncccc23)n1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2cc(F)cc(N3CCCC3)c2)c1C +O=C(COc1ccc(Br)cc1)OCCN1CCOCC1 +COc1ccccc1NC(=O)c1cc(C2CC2)nn1-c1ccccc1 +O=C(Nc1cc2c(cc1Cl)OCCCO2)c1ccc(F)cc1 +COc1cc(NC(=O)c2cc(O)c(OC)cn2)cc(OC)c1 +CCC(OC)C(=O)NC1CCCN(c2ncccn2)C1 +CCc1cc2c(NCc3ccc(S(N)(=O)=O)cc3)ncnc2s1 +CC(C)(C(=O)N1CCCC(N2CCCC2=O)C1)c1cccc(Cl)c1 +c1csc(-c2nc3ncc4c(n3n2)CCCC4)c1 +CC(=O)Nc1ccc(C(=O)Nc2nc3ccc(C)cc3s2)s1 +Oc1cccc(NCc2cnn(-c3ccc(Cl)cc3)c2)c1 +CN(C(=O)CSc1nc2ccccc2[nH]1)c1nccs1 +CCC(C(=O)N1CC(c2ccncc2)C1)N1Cc2ccccc2C1=O +N#Cc1ccc(CCC(=O)N2CCCN(c3nccs3)CC2)cc1 +Cc1n[nH]cc1CN1CCN(Cc2ccc(Cl)cc2)C(=O)C1 +COc1cc(OC)c(-c2n[nH]c(C)c2N)cc1OC +CCN(CC)c1ccc(C(=O)CN2CC(C)OC(C)C2)cc1 +O=C(Nc1nncs1)c1sccc1-n1cccc1 +CC(C)c1nsc(NC2CCC(=O)N(C)C2)n1 +O=C(CCS(=O)(=O)c1ccc2c(c1)CCC2)Nc1ccccc1 +O=C(CCc1ccco1)NCC1COc2ccccc2O1 +O=C(Nc1ccc2oc(=O)ccc2c1)c1cnc(C2CCCO2)s1 +c1cc2c(cc1OCc1nc3c(s1)CCCN3)CCC2 +CC(Sc1nnnn1Cc1ccccc1)C(=O)c1ccccc1 +Cc1cc(NC(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2)[nH]n1 +Cc1ccc2c(c1Cl)CCNC2c1cccnc1C +CCN(C(=O)c1ccc2nncn2c1)S(=O)(=O)c1ccc(C)cc1 +O=C1Cc2cc(NC(=O)C3CC3c3ccc(F)cc3F)ccc2N1 +O=S1(=O)COCCN1Cc1c(F)cccc1F +Cc1ccccc1CNc1nnc(CC(C)C)s1 +CC(=O)NCC(=O)Nc1ccccc1N1CCCC1=O +CC(C)NC(=O)c1ccc(NC(=O)NC(C)C(C)C)cc1 +COC(=O)C1=C(C(C)C)NC(=O)NC1c1cc(OC)ccc1OC +CC(C)(C)OC(=O)N1CCN(C(=O)c2n[nH]c3c2CCCC3)CC1 +Cc1cc(C)c(C(C#N)CC(=O)NCc2ccco2)c(C)c1 +CC(C)(C)c1csc(CNC(=O)NCCc2cccs2)n1 +CCC(CC)NC(=O)c1ccc(OC(F)F)c(OC)c1 +COCCn1c(C)cc(C(=O)CN2CCC3(CC2)OCCO3)c1C +O=C(NCc1cccs1)Nc1ccc(OC(F)F)c(F)c1 +O=C(NCc1ccc(OCC2CC2)cc1)c1cc2n(n1)CCCO2 +Cc1ccsc1C(=O)OCC(=O)NCCc1ccccc1 +Cc1cc(C)n(C2CN(Cc3cnc(C)s3)C2)n1 +COc1ccc(C#N)cc1NC(=O)NCC(C)N1CCOCC1 +COC(=O)c1cccc(-c2cccc(CN3CCOCC3)c2)c1 +CC(C)C(NC(=O)Cc1ccccc1)C(=O)Nc1ccccc1O +COC(=O)c1ccc(N2CCN(c3ccccc3)CC2)c(N)c1 +COC(=O)c1cc(C)ccc1NCc1cnccn1 +CCCc1noc(C(C)Sc2nc(C)cs2)n1 +NC(=O)COc1c(-c2ccccc2)oc2ccccc2c1=O +O=C(Cc1n[nH]c(=O)c2ccccc12)Nc1ccccc1 +Cc1cccc(NC(=O)c2cc(S(=O)(=O)N(C)C)c(C)s2)c1 +O=C(c1cccnc1)N1CCN(Cc2nc3ccccc3s2)CC1 +CC(C(=O)NCc1cccs1)S(=O)(=O)c1ccccc1F +Cc1c(C(=O)NCc2cn[nH]c2)sc2ccccc12 +O=C1CC(c2ccccc2)N(c2nccc(C(F)(F)F)n2)CCN1 +Cn1c(=O)c2c(nc3n2CCN3c2cccc(Cl)c2)n(C)c1=O +COc1cccc(Cn2cc(NS(=O)(=O)c3cnn(C)c3)cn2)c1 +O=S(=O)(NC1CCSc2c(F)cccc21)c1ccc(F)cc1 +Cn1cc(Br)cc1C(=O)NCc1ccccn1 +C#CCOc1ccc(F)cc1NC(=O)NC1C2CCC(C2)C1CO +CCn1cc(C(=O)N(C)C(C)c2ccncc2)cn1 +CCCNC(=O)c1cccc2c1CCN2C(=O)c1ccc(F)cc1 +O=C(Nc1ccc(Cl)cc1N1CCOCC1)c1cccs1 +COC(C)(C)c1noc(CCN2C(=O)COc3ccccc32)n1 +Cc1ccc(C)c(CNC(=O)C(N)Cc2ccccc2)c1 +CC(C)CN1CCOC(CNC(=O)c2c(F)cccc2F)C1 +CSc1cc2c(cc1NC(C)=O)Cc1ccccc1-2 +Cc1nn(C)c2c(=O)n(Cc3ccccc3)cnc12 +CN(C(=O)c1cnn(-c2ccc(Cl)cc2)c1)c1cccc(C#N)c1 +Cc1c(C(=O)NC2c3ccccc3CC2C)cnn1-c1ccncc1 +CCOc1ccccc1N(C)C(=O)c1ccc(OCC(F)F)nc1 +COc1ccc(C(=O)Nc2cccc(SC)c2)cc1 +Cc1cc(C(F)(F)F)nc2nc(NC(=O)C3CC3)ccc12 +CN1CC(C(=O)N2CCN(Cc3nc4ccccc4[nH]3)CC2)CC1=O +CN(CCc1ccc(F)cc1)S(=O)(=O)c1ccccc1F +CCN(CCC(=O)Nc1ccc(N)cc1C)c1ccccc1 +O=C(Cn1ccc2c(Cl)cccc21)Nc1nnc(C2CC2)s1 +CCCn1nc(C(=O)NCCc2ccc(F)cc2)ccc1=O +COc1ccc(CNC(=O)c2ccccc2NC(=O)NC(C)C)cc1 +O=C(c1ccc[nH]c1=O)N1CCCC1Cc1ccccc1Cl +CCn1ccc(NC(=O)c2cc(-c3cccs3)cs2)n1 +O=C(Nc1ccc2c(c1)OCCO2)c1cnc2n(c1=O)CCS2 +O=C(c1cnc[nH]1)N1CCC(=Cc2cc(Cl)ccc2Cl)CC1 +CNC(=O)c1c(NC(C)=O)sc2c1CCCCC2 +Cc1oc(C)c(C(=O)N(C)CC(C)(CO)CO)c1Br +NC(=O)c1cccc(NC(=O)CNc2ccccc2Cl)c1 +Cc1ccc(C2N(c3ccccn3)C(=O)C3CCCN32)o1 +CCOC(=O)c1cc(N)n(Cc2ccc(OC)cc2)n1 +Cc1cc(C)c2c(-n3cccc3)nn(CC(=O)N3CCCCC3)c2n1 +Cc1ccc(OCC(=O)Nc2cccc(O)c2)c(C)c1 +O=C1CN(Cc2cc3c(cc2Br)OCCO3)CCN1 +CC(C)OCCC(=O)NCc1cn(-c2ccccc2)nn1 +CC(=O)N1CCOc2ccc(S(=O)(=O)N=c3cccc(C)[nH]3)cc21 +CN(Cc1ccc2c(c1)OCCO2)C(=O)Cc1cn2ccsc2n1 +CC(C)(C)CC1CCCN1C(=O)Nc1ccc(OCC(N)=O)cc1 +O=C(OCC(=O)N1CCCC1)C1CCCN1C(=O)c1cccs1 +CC(OCCO)C(=O)Nc1c(Cl)cc(N)cc1Cl +Cc1nn(C)c(C)c1NC(=O)c1cc(Br)ccc1Cl +COc1ccc(C(=O)NCc2ccc(F)cc2)cc1Br +Cc1ccc(CCC(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1Cl +Cc1nnc(C23COCC2CN(Cc2cnn(C)c2)C3)o1 +Cc1ccc(NC(=O)CN2C(=O)C(C)(C)Nc3ccccc32)cc1 +CCS(=O)(=O)c1cccc(NC(=O)N(C)CCO)c1 +Cc1nc(C)c(CC(=O)OCc2ncc(-c3ccccc3)o2)c(=O)[nH]1 +COc1ccccc1C(=O)C1CCCN(c2cc(C#N)ccn2)C1 +Cc1ccc(C(=O)N(C)Cc2nc(-c3ccccc3Cl)no2)cc1 +Cc1nc(-c2cccc(NCc3cccc4c3OCCO4)c2)n[nH]1 +Cc1cc(Cl)ccc1NC(=O)Cn1cnc(N)n1 +CC(=O)c1ccc2c(c1)N(Cc1ccccc1)C(=O)CO2 +CC(NC(=O)c1ccc(Cl)cc1N)c1ccccc1 +Cc1ccc(S(=O)(=O)N(C)Cc2ccsc2)cc1C +CCc1noc(CC)c1CC(=O)NCc1nc(C)c(C)s1 +O=C(NCc1ccc(F)cc1)NCc1cccc(Cn2cccn2)c1 +COc1ccc(C(C)=O)cc1CC(=O)NC(C)C(C)C +CNC(=O)c1cc(C)ccc1NC(=O)c1ccc(OC)c(OC)c1 +Nc1nccnc1C(=O)NC(Cc1ccccc1)C1CCCC1 +COc1ccc(F)c(NC(=O)NCCC(=O)OC(C)C)c1 +CCCn1nc(C(=O)Oc2ccc(Cl)cc2C)ccc1=O +C=CCN(CC=C)C(=O)Nc1ccc(OC)cc1OC +CC(=O)NC(C(=O)NCC(C)N1CC(C)OC(C)C1)C(C)C +c1cn(CCc2cscn2)c(-c2ccc3nonc3c2)n1 +CC(C)c1nc(C(=O)OCc2cc3ccccc3[nH]c2=O)cs1 +Cc1ccc(C)c(NC(=O)COC(=O)c2ccoc2)c1 +O=C(Nc1cccc2[nH]nnc12)N1CCCCCC1 +COC(=O)C(NC(=O)Nc1cc(Cl)ccc1C)C(C)C +CCCCN1C(=O)C2(NC(=O)c3ccccc3N2)c2ccccc21 +Cc1ccc(NC(=O)CNC(=O)COC(C)C)c(Cl)c1 +Cn1cc(C(=O)Nc2ccc3ncccc3c2)cn1 +Nc1cccc(C(O)CNc2cccc(C(F)(F)F)c2)c1 +CCc1ccc(C(C#N)CC(=O)NCc2ccccn2)cc1 +O=C(Nc1ccc(F)cc1)c1ncc2n1CCCC2 +COCC1CCCN1C(=O)Nc1ccc(-n2ccnc2)c(Cl)c1 +C=C1C(C(=O)Nc2ccccc2F)C1C(=O)Nc1ccccc1F +O=C(NC1CC1)C1CC(=O)N(CCOc2ccccc2)C1 +CC(C)Cc1n[nH]c(CN2CCN(C(=O)OC(C)(C)C)CC2)n1 +Cc1cccc(CC(=O)N2CCN(Cc3ccsc3)CC2)c1 +CCOc1ncnc(N2CCN(c3ccccc3F)CC2)c1N +CCC(CC)NC(=O)c1nc2nc(C)cc(C)n2n1 +CCNC(=O)C1CCCN(C(=O)Nc2cccc(CC)c2)C1 +Cc1ccc(NC(=O)NC(O)C(Cl)(Cl)Cl)cc1 +CC(C)CNC(=O)CCNC(=O)c1c[nH]c(=O)c2ccn(C)c12 +Cc1ccc(S(=O)(=O)CCC(=O)Oc2cccc(C)c2)cc1 +Cc1cc(C(=O)Nc2ccc(OCC(N)=O)cc2)on1 +CN1C(=O)C(C)(C)COc2c(N)cc(C(F)(F)F)cc21 +Cc1ccc(CCN2C(=O)CCC3CN(c4ncccn4)CCC32)o1 +COc1ccc(-c2nc(NC(=O)c3ccn(C)n3)sc2C)cc1 +O=C(NCC1(c2cccc(C(F)(F)F)c2)CCOCC1)NC1CC1 +CCc1cc2c(=O)n(CC(=O)N3CCN(C(C)=O)CC3)cnc2s1 +COCCOCC(=O)N1CCCN(Cc2ccc(C#N)cc2)CC1 +Fc1cc(Br)ccc1CN1CCOCC1 +CS(=O)(=O)NCCCNC(=O)N1CC=C(c2ccccc2)CC1 +O=C(Cn1c(CCCO)nc2ccccc21)N1CCCCC1 +O=C(NCc1csc(-c2cccs2)n1)c1ccccc1 +O=C(CS(=O)(=O)c1nc2ccccc2[nH]1)NCCc1ccccc1 +Cc1oc(C)c(C(=O)NCc2ccccc2Cn2cncn2)c1C +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1c(C)cccc1C +Cn1cnc(CNC(=O)c2sccc2S(=O)(=O)C(F)F)n1 +CC(CO)CNC(=O)NCc1ccc(F)cc1C(F)(F)F +CN(C)C(=O)Cn1cc(C(=O)Nc2cc(C#N)cn2C(C)(C)C)nn1 +CC(C)(CNC(=O)Cn1ncc(=O)c2ccccc21)c1ccncc1 +Cc1cccc(C)c1OCc1ncc(CC#N)s1 +O=C(c1noc2ncnc(N3CCOCC3)c12)N1CCCCC1 +O=C(NCC1Cc2ccccc21)c1ccc(OCC(F)F)nc1 +COCc1ccccc1NC(=O)c1ccc(OCC(F)F)nc1 +COc1ccc(CNS(=O)(=O)c2ccc(C(F)(F)F)cc2)cc1 +CCOC(=O)C1CCCCN1Cc1noc(CC)n1 +COCCn1nc(C(=O)NC2CCSc3ccccc32)ccc1=O +Nn1c(SCC(=O)N2CCCCC2)nnc(-c2ccccc2)c1=O +Oc1cc2c(cc1F)CCNC2c1c(F)ccc(F)c1F +CCCCCCn1c(=O)c2c(nc3oc(C)c(C)n32)n(C)c1=O +Oc1ccc2c(c1)oc1c(-c3cccnc3)c3cn[nH]c3nc12 +Cc1cc(CN2CCN(C3=NS(=O)(=O)c4ccccc43)CC2)no1 +CNC(=O)NCC(=O)N(Cc1ccccc1)CC1CCC1 +COc1ccc2[nH]cc(CC(=O)N3CCCC(CCC(N)=O)C3)c2c1 +C=CCN(CC=C)C(=O)C1(C)Oc2ccc(Cl)cc2NC1=O +CCC(C)c1noc(C2CCN(C(=O)Cn3nc(C)cc3C)CC2)n1 +Cc1cc(C)n(Cc2ccccc2Cl)c(=O)c1C#N +CCOC(=O)c1cnc(COc2ccccc2F)nc1N +N#CC1(NC(=O)CNc2cccc(F)c2)CCCC1 +CCNC(=O)CN(C)C(=O)C(OCC)c1ccccc1 +CC(=O)Nc1ccc(C(=O)C(C)OC(=O)c2ccnnc2)cc1 +Cc1nc(CC(=O)Nc2ccc(OCC(N)=O)cc2)cs1 +COCCS(=O)(=O)N1CCCC(C)(C)c2ccccc21 +CC(C)n1nc(CN2CCOCC2)c2c1CN(C(=O)c1ccno1)C2 +Cc1ccc(CC(=O)NCc2cccc(Cn3cccn3)c2)s1 +CC(=O)c1ccc(OCc2cccc(C(N)=O)c2)cc1 +Cc1ncn2cc(-c3ccc(Cl)cc3Cl)[nH]c(=O)c12 +Cn1cc(CCCNC(=O)Nc2cc(C3CCC3)nn2C)cn1 +CCOc1ccc2cc(C(=O)N3CCN(CCO)CC3)c(=O)oc2c1 +COc1ccc(-c2csc3nc(SCC(N)=O)nc(N)c23)cc1 +O=C(NCCCn1cnnc1)c1cn(-c2ccccc2)nn1 +O=C(COC1CCCC1)NCCNC(=O)c1ccccc1Cl +Oc1ccc(C2NCCc3c(Cl)cc(O)cc32)cc1 +CCCC(NC(=O)NCc1nnc2n1CCCCC2)c1ccccc1 +CCOC(=O)c1c(C)nc(N)nc1-c1cc(C)no1 +CNc1nc(CNC(=O)Nc2cnc3c(c2)c(C)nn3C)cs1 +COc1ccc(C)cc1C(O)CNc1ccc(C#N)cc1 +CCC(O)C1CCN(C(=O)c2cn(Cc3ccccc3F)nn2)CC1 +O=C(Cc1noc2ccccc12)Nc1ccccc1N1CCCC1=O +COc1cccc(C(=O)N(C)Cc2ccncc2)c1 +COc1cc(C(=O)Nc2cc(C(F)(F)F)ccc2Cl)on1 +O=C(c1c(-c2ccccc2)nnc2ccccc12)N1CCCC1 +Cc1cccc(Cn2cccc(C(=O)N3C(C)COCC3C)c2=O)c1 +CNC(=O)c1ccc(NC(=O)NCc2ccncc2)cc1 +O=C(CC1(CC(=O)N2CCCC2)CCCCC1)Nc1nccs1 +CN(C)S(=O)(=O)N1CCC(C(=O)NCC2CCCCC2)CC1 +CCCOc1ccc(CCC(=O)N2CCCC(O)C2)cc1 +CC(c1cccs1)N(C)C(=O)c1ccc(C#N)cc1 +CCOc1cc(C(N)c2nc(C)c(C)s2)ccc1O +CCOc1ccccc1CNC(=O)c1cc(F)ccc1F +CCc1nccn1-c1cncc(C2CCCN(c3ccnc(C)n3)C2)n1 +CNc1ncc(Br)cc1C(=O)Nc1ccncc1 +c1coc(CN2CC3OCCN(CC4CCCO4)C3C2)c1 +Cc1ccccc1-c1nc(N)n(C(=O)c2ccco2)n1 +C#CCNC(=O)NCCOc1ccc(C(C)C)cc1 +O=C(c1cc2ccccc2o1)N(Cc1ccco1)Cc1ccco1 +Cc1c(C(=O)NCc2cccnc2)oc2ccc(Br)cc12 +COCCOc1ncccc1C(=O)Nc1cccc(Cl)c1Cl +Cc1cc(CNC(=O)c2cc(Cl)c3c(c2)OCO3)c(C)o1 +Cc1cccc(C)c1NC(=O)NCCCc1cn[nH]c1C +Cn1cc(C(=O)OCC(=O)Nc2ccc(Cl)cn2)c2ccccc21 +COc1cc(C)sc1C(=O)OCc1nc2ccccc2[nH]1 +CCc1nc(-c2ccc(Cl)cc2)n2c(=O)[nH]nc2c1C +CNC(=O)c1cccc(CCNCc2cccc(F)c2F)c1 +CCc1noc(CC)c1CNC(=O)C1CC1c1ccc(F)cc1F +O=C1COc2cc(NC(=O)C3CCOCC3)ccc2N1 +Cn1ccc(NC(=O)CCc2ncc(-c3c(F)cccc3F)o2)n1 +CCC1=C(C(=O)OC(C)C)C(c2cccc(F)c2)NC(=O)N1 +COc1cc(OC)c(NC(=O)c2cccc(OC)c2F)cc1F +CCn1c(C)cc(C(=O)NCc2cccc(C)c2)c1C +Cc1ccc(N)c(C)c1NC(=O)c1ccc(Cl)cc1O +CC1c2ccsc2CCN1Cc1nc2ccccc2c(=O)[nH]1 +CN(C)c1oc(COc2ccc(Cl)cc2)nc1C#N +CC(C)C(=O)Nc1cccc(NC(=O)NCc2ncn(C)n2)c1 +COc1cc2ncnc(NC(C)c3ccccn3)c2cc1OC +Cc1coc(-c2ccc(C)c(NCc3nsc(N(C)C)n3)c2)n1 +CC(CC1CCCCC1)C(=O)N(CCC#N)Cc1cccnc1 +OCc1cn(Cc2sccc2Br)nn1 +CCCn1cc(NC(=O)N2CCC(Oc3cccc(Cl)c3)C2)cn1 +Cc1cc(S(=O)(=O)N(C)Cc2ccco2)cc2c1NC(=O)C2(C)C +CCC(C)NC(=O)c1cnn(-c2ccc(OC)nn2)c1C(F)(F)F +CN(C)C(=O)CN(C)C(=O)c1ccc(Cn2ccccc2=O)o1 +COCC(c1ccccn1)N(C)C(=O)c1cnc(N(C)C)nc1C +Cc1ccc(-c2ccc(C(=O)NCC(C)CCO)s2)o1 +CN(C)S(=O)(=O)c1cccc(NC(=O)NCC2(C)CCCC2)c1 +CCOCCOC(=O)C1CC1c1ccc(F)cc1 +CCCOCCC(=O)Nc1ccc(Br)cc1 +Cc1cccc(NC(=O)c2c(C)nc3ccccn23)c1C +CC(C)c1ccc(C(C#N)CCC(=O)N(C)C)cc1 +CS(=O)(=O)NCCNS(=O)(=O)c1cc(N)ccc1Cl +Cc1ccc(-c2nnn(C(C)C(=O)NC3CCCC3)n2)cc1 +Cc1ccc(CNC(=O)c2ccc(=O)n(C)c2)c(OC(C)(C)C)c1 +CCCN1CCN(C(=O)CCn2cc(Br)cn2)CC1 +Cc1sc(NC(=O)Cc2csc(-c3ccco3)n2)c(C#N)c1C +COc1ccc(CNC(=O)NCCc2cc(C)no2)cc1OC +Cc1nn(-c2ccccc2)c2c1C(c1cccc(O)c1)CC(=O)N2 +CC(=O)c1ccc(C(=O)Nc2nnc(C3=COCCO3)o2)cc1 +Cc1oc(C(C)C)nc1C(=O)N(C)CCc1ccncc1 +CC(C)OCC(=O)NCC(=O)Nc1ccccc1 +Cc1ccncc1NC(=O)N1CCCC1CN1CCOCC1 +CC(C)c1nc2cc(C3CCC(=O)C3)ccc2n1C +Nc1ccccc1NC(=O)CCCN1CCCC1=O +COC(=O)c1cccc(NCc2ccncc2)c1C +CC(C)NC(=O)c1ccc(NC(=O)CNc2ccccc2Cl)cc1 +CCN(C(=O)CNc1ccc(Cl)cc1F)C1CC1 +CCc1c(C(=O)N(C)CCOC)[nH]c(C)c1C(C)=O +O=C(CNc1cccc(C(=O)N2CCCCC2)c1)NC1CCCCC1 +Cc1onc(-c2ccccc2Cl)c1C(=O)N1CC(C)OC(C)C1 +c1cncc(CSc2nnc(-c3cnccn3)o2)c1 +CC(=O)Nc1ccccc1OCc1nc(Cc2ccccc2)no1 +O=C1CCCN1c1ccc(OCc2cn3cccnc3n2)cc1 +CCC1CN(CCNc2ccccc2Cl)CCO1 +CCc1ncc(C(=O)Nc2nnc(C)s2)c(N)n1 +CCC(CC#N)NC(CC)c1cccc(Br)c1 +Cn1cc(C#N)cc1C(=O)N1CCC2(CCCN(CC3CC3)C2=O)C1 +CCOC1CCCN(C(=O)N2C(C)CCCC2C)C1 +CNC(=O)c1ccc(CNc2cccc(NC(=O)C(C)C)c2)cc1 +COc1cc(C(=O)N2CC3CCC2CN(c2ncccn2)C3)ccn1 +COC(=O)CCN(C)S(=O)(=O)c1ccc(C)c(F)c1 +CNC(=O)C1CCN(c2nc3ccccc3s2)CC1 +COc1cccc2c(=O)c(C(=O)Nc3ccc(C(C)=O)cc3)c[nH]c12 +CC(=O)N(Cc1ccc(NC(=O)C(NC(N)=O)C(C)C)cc1)C1CC1 +CCOc1ccc(NC(=O)Nc2ccc3c(c2)CC(=O)N3)cc1 +O=C(CCCNc1ncccn1)N1CCCC1Cn1cccn1 +CC(C)Oc1ccccc1NS(=O)(=O)c1ccccc1 +Cc1ccc2ncc(CN(C)C(C)Cc3ccc(O)cc3)n2c1 +CCN(CC1CCOC1)C(=O)Nc1ccc2nn(C(C)C)cc2c1 +CCc1nncn1CCNC(=O)c1cc(F)cc(Cl)c1O +CCn1c(C)cc(C(=O)NCc2ccc(OC(C)C)nc2)c1C +Cc1ccc(-c2csc(NC(=O)CSc3nncn3C)n2)cc1 +O=C(Nc1c(Cl)cccc1Cl)c1cc2ncccn2n1 +COc1ccc(CNC(=O)c2cccs2)cc1O +CN(C)C(=O)c1ccc(C(=O)NC(c2ccccc2)C2CC2)cc1 +COCCOc1cccc(CNc2c(C)cccc2C)c1 +CC(C)(C(=O)NCc1nnc2n1CCCCC2)c1ccccc1F +CSc1nn(CCCc2ccccc2)c(N)c1C#N +COc1ccc2c(c1OC)C(c1cccnc1C)NCC2 +Cc1ccc(Cn2nc(-c3nc(-c4ccncc4)no3)ccc2=O)cc1 +Cc1cc(F)cc2c1N(C(=O)c1cscn1)CCC2 +C#CCNC(=O)c1ccn(-c2ccc(OC)cc2)n1 +CC1c2ccccc2CCN1C(=O)c1n[nH]c2ccccc12 +CCOc1ccc(N(CCC#N)C(=O)c2cccc3c2OCO3)cc1 +Cc1ccccc1C(CC(=O)NC1CCCCCC1)NC(N)=O +O=C(Nc1ccc(O)cc1F)c1cnn2c1CCCC2 +CNC(=O)c1ccc(CN(C)C(=O)c2cccc3ccc(C)nc23)cc1 +COCCn1c(SCc2ccccc2C)nc(C)c1C +CC(C)Oc1ccccc1C(=O)N1CCC(O)(C(F)(F)F)CC1 +CCOc1nnc(CN2CCN(c3cccc(F)c3C#N)CC2)s1 +Cc1cc(C(=O)N2CCOCC23CCC3)c(C)cc1Br +CCCc1ncc(C(=O)NCc2cccnc2)c(N)n1 +CCc1nnc2c(NC(=O)Cc3ccc(OC)c(Cl)c3)cccn12 +CC(=O)NCCNC(=O)c1cc(Cl)c2c(c1)OCO2 +CC(NC(=O)N(Cc1ccncc1)C1CC1)c1nncn1C +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)OC1CCOC1=O +Cc1nc(C(C)(C)NC(=O)C2COc3ccc(F)cc3C2)sc1C +COc1cc2c(cc1F)CCNC2C(O)C(C)C +Cc1ccc(CN(C)S(=O)(=O)Cc2ccccc2)s1 +COc1ccc(C(C)C)cc1C(CC(N)=O)C1CC1 +COC(=O)C(C)(C)NC(=O)C1CC(=O)N(c2ccccc2Cl)C1 +O=C(Nc1cccc(C(=O)N2CCCC2)c1)c1cccnc1 +CS(=O)(=O)NC1CCN(Cc2nc(C(F)(F)F)cs2)C1 +O=C(NCc1cc2c([nH]c1=O)CCC2)NCC(F)(F)F +CC(C)CC(=O)N1CCN(C(=O)CC(C)C)C(C)C1 +Cc1ccccc1-c1nnc(SCCC(N)=O)o1 +COc1ccc2c(C)c(CC(=O)NC3CC3)c(=O)oc2c1C +C#CCN1CCN(C(C)C(=O)N(CC=C)CC=C)CC1 +CCC(NCCc1ccncc1)c1ccc(Cl)cc1 +CCCCCCNS(=O)(=O)c1nc2nc(C)cc(C)n2n1 +COC(=O)CCC(=O)c1cc(C)c(OC)cc1C +CCOc1ccc(C(=O)NC(C)C)cc1Br +Cc1nc2c3c4c(sc3nc(C)n2n1)CCC(C)C4 +CC(C)Oc1ccc(C(C)NC(=O)c2cc(C(N)=O)cs2)cc1 +Cc1nc(C2CCCN(C(=O)c3ccncc3)C2)sc1C +CCCC(=O)N1CCc2nc(NC(=O)C3CCCO3)sc2C1 +Cc1cc(C)nc(SCC(=O)N2CCn3cccc3C2C)n1 +CC(C)=CC(=O)OCC(=O)Nc1cc(C)cc(C)c1 +CN1CCN2CCN(Cc3cccc4cnccc34)CC2C1=O +CCc1ccc(CN2CCN(C(=O)c3ccccc3)CC2)nc1 +CCCn1c(CNc2ccc3c(c2)OCC(=O)N3)nc2ccccc21 +O=C(COc1ccc(F)cc1)N1CC(c2nc(-c3ccco3)no2)C1 +CCC(=O)NCCc1cc2ccc(OC)cc2[nH]c1=O +O=C(NCc1ccc(C(O)c2cccs2)s1)c1ccco1 +CCS(=O)(=O)NCc1nnnn1-c1ccc(Cl)cc1 +CCc1nnc(NC(=O)c2ccccc2-c2ccccc2C#N)s1 +CC(C)CC(CNC(=O)Nc1ccc2nncn2c1)N1CCOCC1 +COc1ccc2cc(CNC(=O)CCOC(C)C)ccc2c1 +CC(C)(C)c1noc(CCC(=O)Oc2cccc(F)c2)n1 +Cc1cc(C)n(CC2CCCN2C(=O)CCc2nc(C(C)C)no2)n1 +NC(=O)COc1ccc(NC(=O)Cc2ccc(F)cc2F)cc1 +Cc1nc(CN2CC3(CCN(C(=O)c4ccoc4)C3)CC2=O)cs1 +CC1CN(C(=O)c2ccc(-c3cscn3)cc2)CC(C)O1 +Cc1cc(NC(=O)C2CCC(=O)N2Cc2cccs2)no1 +N#Cc1cccc(NC(=O)CCSc2ccc3c(c2)OCCO3)c1 +CCc1ncsc1C(=O)N(C)c1cccc2ncccc12 +O=C(COc1ccccc1F)NCCC(O)c1cccs1 +CCOC(=O)c1[nH]c2ccc(F)cc2c1NC(=O)OC +OC(c1cccnc1)(c1cccs1)C(Cl)(Cl)Cl +COc1c(C(=O)NC(Cc2ccccc2)C2CC2)c(C)nn1C +Cc1nccn1-c1cc(CNC(=O)C2CC=CCC2)ccn1 +COc1ccccc1C1C(C(N)=O)C(C)=Nc2ncnn21 +Cc1nn(C)cc1-c1ccnc(N(C)Cc2ccon2)n1 +Cc1cc(C(=O)N2CCCC2(C)C)nn1-c1ccccc1 +CC(CC#N)N(C)Cc1ccc(F)c(Br)c1 +Cc1ccc2c(ccn2CCC(=O)Nc2nnc(C(C)C)s2)c1 +COc1cccc(C(=O)NCCC(=O)Nc2cccc(Cl)c2C)c1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cc1 +COc1ccc(S(=O)(=O)N(C)C(=O)c2cc(C)cc(C)c2)cc1 +O=C(OCc1nnc(C2CC2)o1)c1cc2c(s1)CCC2 +c1coc(-c2noc(CN3CCN(c4nccs4)CC3)n2)c1 +CC(=O)N1CCCN(C(=O)c2sccc2Br)CC1 +CCc1ccccc1C(=O)N1CCC(OCc2ccccc2C)CC1 +Cc1nc(C(=O)Nc2ccccc2C(=O)N(C)C)cs1 +CCc1csc(C2CCCN(C(=O)CCCc3ccccn3)C2)n1 +CC(OC(=O)c1nc(N2CCCC2)ncc1Cl)c1ccccn1 +O=C(NCc1ccncc1)c1nc(-c2ccc(F)cc2)no1 +O=C(NCCc1c(Cl)cccc1Cl)Nc1cccnc1 +CC(=O)Nc1ccc(NC(=O)CCc2nc3ccccc3s2)cc1 +CCOC(=O)CCC(C)NC(=O)c1cc2cccc(F)c2o1 +CCOC(=O)N1CCN(CC(=O)NC(C)(C#N)C(C)C)CC1 +CC(CN1CCOCC1)NC(=O)c1ccc2ncsc2c1 +Cc1[nH]c2c(C)ccc(C)c2c1CC(=O)NC1CCCCC1O +O=C(NCc1nccs1)c1ccc2c(c1)OCCO2 +CN(C(=O)C1CC(=O)N(CCN2CCOCC2)C1)c1ccc(F)cc1 +CN1C(=O)c2ccc(Cl)cc2NC1c1ccccc1F +Cc1c(C2CC2)nn(-c2ccccc2)c1NC(=O)CCCn1cccn1 +Nc1nn(-c2ncccc2Cl)nc1C(F)(F)F +Cn1cc(CNC(=O)N(Cc2ccc(F)cc2)C2CC2)cn1 +Cc1nc(-c2ccc(C(=O)NCCc3ccc(F)cc3C)cc2)n[nH]1 +CCNc1cc(CSc2ncc(C)cn2)ccn1 +CCOc1ccc(SCC(=O)NC(C)c2ccncc2)cc1 +CN(C)C(=O)Cn1cc(C(=O)NCC2CCC(C)(C)CC2)nn1 +CCn1nc(C(=O)Nc2nc3c(s2)CCc2ccccc2-3)cc1C +CCc1ccc(NC(=O)Cc2ccc(N3CCCC3=O)cc2)cc1 +CC(Oc1cccc(C#N)c1)C(=O)N1CC(C)C(N2CCOCC2)C1 +CCc1nnc(NC(=O)NC2(c3nc(C)cs3)CCCC2)s1 +Cc1ncsc1Cc1cnc2sccn2c1=O +CCCC1CN(C(=O)c2cnc(N)c(Cl)c2)CCO1 +O=C1CCC(C(=O)Nc2ccc(OCC(F)(F)F)nc2)CN1 +C=CCN1CCN(C(=O)Cc2ccc(OCC)cc2)CC1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)CCC1CCCO1 +COc1ccccc1CN1CCCCS1(=O)=O +CCN(CC1COc2ccccc2O1)C(=O)NC(C)c1nncn1C +CCCNc1nnc(Sc2ccc3nccnc3n2)s1 +Cc1ccc(OCC(=O)Nc2ccccc2N2CCCC2=O)c(C)c1 +Fc1ccc(C=Cc2nn3c(-c4ccncc4)nnc3s2)cc1 +O=C(Nc1ccccc1Cl)N1CCc2c(nc[nH]c2=O)C1 +O=C(CC1COc2ccccc2O1)Nc1ccc(Br)cc1 +Cc1ccccc1N1CC(C(=O)NCCc2ccc(F)cc2)CC1=O +O=C(NCCCc1ccc(O)cc1)c1cnc(-c2cccnc2)nc1 +CC(=O)Nc1ccc(Cl)c(NC(=O)NCCCC(C)C)c1 +Cc1ccc(Nc2ncnc(N3CCOCC3)c2N)c(C)c1 +Cc1nn(C)cc1S(=O)(=O)n1cc(Cl)cn1 +CCOC(=O)c1cc(S(=O)(=O)N2CCCCC2)ccc1Cl +O=C(Nc1nccs1)c1ccc(O)c(Cl)c1 +Cc1noc(C2CCN(C(=O)COc3ccccc3C)CC2)n1 +CNC(=O)NCC(=O)N1CCC(OCCC(C)C)C1 +O=C(NCCc1ccc2c(c1)OCO2)Nc1cn[nH]c1 +COc1ccc(CN2C(=O)C3=C(CCCC3)C2OC)cc1 +CCC(C)OC(=O)Cn1c(-c2ccccn2)ccc(C#N)c1=O +C#CCNC(=O)c1ccc(S(=O)(=O)NCC(C)C)cc1 +O=C(c1ccon1)N1CCc2ccc(Cl)cc2C1 +CCc1nnc(NC(=O)Nc2cccc(OC(F)F)c2)s1 +COC(=O)c1cc(S(N)(=O)=O)c(Br)cc1OC +COc1cccc(-n2nnnc2SCC(=O)c2ccc(F)cc2)c1 +O=S(=O)(Nc1cccc(CO)c1)c1ccccc1Br +Cn1ncc2c(NC3CCN(C(=O)C4CC4)CC3)ncnc21 +Cc1cc(C(=O)N2CCC(C)CC2)c2cnn(C(C)C)c2n1 +COCC(=O)N(C)CC(=O)Nc1cc(F)ccc1OC +C=CCNC(=O)c1c(N)n(CCCC)c2nc3ccccc3nc12 +COc1cc2c(cc1OC)CN(C(=O)CCc1n[nH]c(C)c1C)CC2 +CCCC(C)NC(=O)c1ccc(OC)cc1OC +CCOC(=O)CN(C)C(=O)c1ccccc1SC +COc1ccc(CC(=O)N(C)Cc2nnc3ccccn23)cc1 +Cc1cc(N2CCOC(c3cc4cccnc4[nH]3)C2)ncn1 +CCOc1ccc(C(=O)N2CCc3cc(F)ccc3C2)cc1 +CCc1ccc2c(c1)C(c1c[nH]c(=O)c(Cl)c1)NCC2 +CCCNC(=O)c1c(Br)cnn1CC +O=C(Nc1ccccc1-n1ccnn1)c1ccnnc1 +O=C(Nc1ccc2c(c1)OCO2)c1cccnc1OCC(F)F +CCn1nc2c(C)cc3cc4c(cc3n2c1=O)OCO4 +Cc1nnnn1-c1cccc(C(=O)N2CCN(c3ccccc3)CC2)c1 +CC(=O)c1ccc(NC(=O)CC2C(=O)OCCN2C)cc1 +C=CCSc1nnc(-c2cc(N(C)C)nc(N(C)C)n2)n1C +Cc1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)s1 +COC(=O)CCN(C)C(=O)c1ccc(F)c(F)c1 +O=C(Nc1nnc(C2CC(=O)N(c3ccccc3)C2)o1)c1ccco1 +COC(=O)C1CCN(C(=O)c2ccc(SC)cc2OC)CC1 +Cc1ccc(-c2nnc(SC(C)C(=O)NCc3ccco3)o2)cc1 +Cc1cccc(CNC(=O)NC(C)COc2ccc(F)cc2F)n1 +Cn1c(=O)n(C)c2cc(COC(=O)CNC3CC3)ccc21 +CSc1ccccc1NC(=O)N1CCC(Oc2ccccc2)CC1 +N#Cc1cccc(C(=O)NC(C(=O)Nc2cc[nH]n2)c2ccccc2)c1 +CCNC(=O)CNS(=O)(=O)c1ccc(N)cc1 +COc1ccc(CCn2cc(N)cn2)cc1C(C)C +CCCOc1ccccc1C1CC(=O)Nc2[nH]nc(C)c21 +CCC(CC)c1nc2cc(F)c(F)cc2n1CCO +Cc1ccc2c(c1)CCCN2C(=O)c1cc(C(N)=O)cs1 +CCn1c(SCC(=O)Nc2cccc(C)c2)nnc1C1CC1 +Cc1ccnc2nc(C(=O)NCCc3nc(C(C)(C)C)cs3)nn12 +O=C(COc1ccccc1)Nc1ccc(-c2cnco2)cc1 +CCC(CC)C(O)CNC(=O)NCc1nc(C)cs1 +Cc1cc(-c2nnn(Cc3ccc(F)cc3C#N)n2)ccc1F +COc1cccc(C(=O)Nc2ccc3nn(C(C)C)cc3c2)c1F +O=C(Cc1c[nH]c2ccccc12)OCC(=O)C1Cc2ccccc2O1 +CC(c1ccccc1)c1cc(C(=O)N(C)Cc2ccsc2)on1 +CCCc1nnc(NC(=O)Cc2cccc(F)c2)s1 +C=CCOC(=O)C1CC(=O)N(c2cccc(Br)c2)C1 +Cc1cnc2c(c1SCC(=O)N1CCCC1)c(=O)n(C)c(=O)n2C +Cc1cc(NC(=O)CCSc2ccc(Cl)cc2)no1 +COC(=O)CCC(=O)Nc1cccc2c1OCCO2 +O=C(CC1CCCCC1)N1CCc2ncccc2C1 +Cc1c(C(=O)OCC(=O)Nc2sccc2C#N)oc2ccccc12 +Cc1ccc(N2C(=O)NCC2c2ccccn2)cc1 +O=C(CCn1nnc2ccccc2c1=O)N1CCCCCC1 +CC1CCN(C(=O)c2cn(-c3ccc(C#N)cc3)cn2)CC1 +O=S(=O)(Cc1noc(C2CC2)n1)c1ccccc1F +Cc1c(-c2nc(-c3ccc(C#N)cn3)no2)cnn1-c1ccccc1 +O=C(Nc1cccc(-c2ncco2)c1)N1CCC(n2cccn2)CC1 +Nc1ccc(S(=O)(=O)NCc2cn[nH]c2)cn1 +Cc1n[nH]cc1CNC(=O)COc1cccc(F)c1 +Cc1nc2ccccc2n1C(=O)Cc1ccccc1 +Cc1cc(C)c(C(=O)N2CC3CCCC3C2)c(=O)[nH]1 +O=S(=O)(NCCC1CCCO1)c1ccccc1Br +CCCn1c(=O)n(CC(=O)NC(C)C2CCCO2)c2ccccc21 +Cc1ccc(-c2c(C)sc3ncnc(N(C)CCO)c23)cc1 +Brc1ccn2nc(N3CCCC3)ncc12 +O=C(Cc1cccc(F)c1)Nc1ccc(CN2CCCC2=O)cc1 +NC(=O)c1cc2c(nc1CC1CCCCO1)CCC2 +CN1C(=O)Cc2cc(NS(=O)(=O)c3ccc(Cl)cc3)ccc21 +CC(C)c1nn2cc(C#N)cnc2c1Br +Nc1cc(-c2ccccc2)nn1S(=O)(=O)c1ccc(Cl)cc1 +O=C(NC1CCCCC1)c1ccc(=O)n(Cc2ccccc2)n1 +C#CCC(N)c1nc(C)c(C(=O)OCC(C)C)s1 +CCC(CC)NC(=O)c1ccc(-c2nc(C)no2)cc1 +O=C(c1nccc2ccccc12)N1CCCC1c1ccc[nH]1 +Cn1nccc1-c1cccc(-c2n[nH]c(CO)n2)c1 +O=C(CO)N1CCN(CCOc2ccccc2)CC1 +CS(=O)(=O)N1CCC(N2CCOCC2)C1Cc1ccncc1 +Cc1n[nH]cc1CNC(=O)C1CCCN(S(C)(=O)=O)C1 +CC(C)(C)OC(=O)N1CCN(c2ncccc2C(N)=O)CC1 +CS(=O)(=O)N1CCCN(C(=O)c2ccc3ccccc3c2)CC1 +CC(=O)c1c(-c2ccc(C)c(C)c2)cnn(C)c1=O +Cc1ccc(S(=O)(=O)Nc2ccc(F)c(N)c2)s1 +CCc1nc2sc3c(n2n1)CCNC3Cc1ccccc1 +CC(C)(O)c1nnc(C(N)c2ccc(C#N)cc2)o1 +Cc1cccc(CS(=O)(=O)N2CC(c3nc(C)no3)C2)c1 +CCS(=O)(=O)N(Cc1ccc(C(=O)NC)cc1)C1CC1 +CC(=O)NCC1CCCN(C(=O)Nc2cccc(F)c2F)C1 +Cc1cc(C)n(-c2ncnc(Sc3ccccc3)c2N)n1 +CCOc1cccc(C(=O)Nc2cccc(C(=O)OC)c2C)c1 +CCc1ccc(CCNC(=O)NC2CCCn3nc(CC)nc32)cc1 +COC(=O)c1cccc(C(=O)Nc2ccc(C)cc2OC)c1 +Cc1c(C(=O)N(C)Cc2cccs2)[nH]c2c1C(=O)CCC2 +O=C(Nc1cccc(Br)c1)c1ccc2nccnc2c1 +CS(=O)(=O)c1ccccc1NC(=O)Cc1ccc2ccccc2c1 +O=c1[nH]nc2cc(-c3ccccn3)nc(-c3cccc(Cl)c3)n12 +CCOc1ccc(CC(=O)Nc2ccccc2N2CCOCC2)cc1 +CCOc1ccc2cc(C(=O)NCCCOC)c(=O)oc2c1 +CC(=O)c1csc(NC(=O)c2nn(C)c(=O)c3ccccc23)n1 +Cc1nccc(C2CC3CCN(C(=O)c4cccn4C)CC3O2)n1 +Cc1ccc(-c2n[nH]c3c2CN(Cc2cnc(C)s2)CC3)cc1 +CC(=O)c1ccc(NC(=O)C2CCN(C(=O)N(C)C)CC2)cc1 +Clc1ccc(NCc2nnnn2C2CC2)cc1Br +CCCc1noc(CNc2ccccc2-n2cccn2)n1 +CC(C)(C)c1nnc(NC(=O)NCC2Cc3ccccc3O2)s1 +CC(C)(C)OC(=O)Nc1ccccc1NC(=O)c1ccc[nH]1 +CC(C)(C)OC(=O)NCc1c(F)ccc(N)c1F +Cc1cc(F)cc(C(=O)NC(c2ccccc2)c2nnc(C)n2C)c1 +CCN(CCO)C(=O)NC(C)Cc1ccccc1F +COCCC(C)NC(=O)Nc1cnn(-c2ccccc2F)c1 +CCN(CC)C(=O)NCCCc1c(C)noc1C +CCCn1cnc2c1c(=O)n(CC)c(=O)n2-c1ccccc1 +CC(NC(=O)c1cc(COc2cccc(F)c2)[nH]n1)c1n[nH]c(=O)[nH]1 +Cc1nc(-c2nn3c(-c4ccc(F)c(F)c4)nnc3s2)co1 +O=C(NCCO)Nc1ccccc1Oc1ccccc1 +Cc1c(C(N)=O)nnn1-c1ccc(F)c(Cl)c1 +COc1cc(OC)cc(C(=O)Nc2cnc3ccccc3c2)c1 +CCN(CC)C(=O)CN1CCN(c2ccc(F)cc2)C1=O +COCC(NC(=O)c1cnn(-c2ccccc2C)c1)C(N)=O +Cc1cccc2c(=O)n(CC(=O)N3CCOCC3C3CC3)cnc12 +CCSc1nc(C)cc(C(=O)NCCCOC)n1 +Cc1ccccc1C(=O)NC(C(=O)N1CC(C)OC(C)C1)C(C)C +COc1cccn(CC(=O)N(C)Cc2cc(C)nn2C)c1=O +O=C(NCc1ccoc1)Nc1ccccc1SC(F)F +CCC(C(=O)NCCn1ccc(-c2ccncc2)n1)c1ccccc1 +COc1cccc(C(=O)N2CCOCC2c2ccc(C)o2)c1F +Nc1nc(N)nc(COC(=O)c2cccc(-c3ccoc3)c2)n1 +Cn1cc(CN2CCN(c3nccs3)CC2)cn1 +Cc1noc(C)c1CC(=O)N1CCNC(=O)CC1c1ccccc1 +COCC(O)CN(C)c1cccc(F)c1C(C)=O +COc1cc(C(=O)NCCc2ccc(F)cc2C)cc(OC)c1OC +Cc1ccc(C(O)CNC(=O)c2cccs2)c(C)c1 +CC(C)CNC(=O)C1CC2CN(CCc3ccccc3)CC1O2 +N#Cc1cccc(NC(=O)CCn2[nH]c(=O)ccc2=O)c1 +C=CCn1ccnc1-c1nc(-c2ccccc2)cs1 +NC(=O)C(Sc1nc(Cc2cccs2)n[nH]1)c1ccc(F)cc1 +COc1ccc(OC)c(C(=O)CNC(=O)Cc2ccccc2)c1 +O=C1NCCN(C(=O)CCCc2cn[nH]c2)C1Cc1ccccc1 +Cc1nc2nc(C)c3c(=O)n(CCO)ccc3n2n1 +COc1ccc(-c2ncc(C(=O)N(C)Cc3ccncc3)s2)cc1 +O=C(Nc1nccs1)c1n[nH]c2c1COc1ccccc1-2 +COc1cc(CNC(=O)NCc2ccc3c(c2)CCC3)ccn1 +Cc1ccc2nc(C)cc(C(=O)N(C)Cc3cc(C4CC4)on3)c2c1 +O=C(OCc1nnc(-c2ccccc2)o1)c1cccc2ncccc12 +COc1cccc(C(CNC(=O)Nc2ccc3c(c2)OCO3)OC)c1 +COc1ccc(Br)c(C(=O)NC2CCCC2OC)c1 +Cc1ccc(CS(=O)(=O)NCCN(C)c2ccccc2)cc1 +O=C(c1ccnc(N2CCOC(C(F)(F)F)C2)c1)N1CCCC1 +COCCCN(C)C(=O)c1ccc(Cl)cc1O +CCC(C)NC(=O)C1CCN(C(=O)Nc2cccs2)CC1 +COC(=O)Cc1cccc(OC(=O)c2ncn(-c3ccccc3)n2)c1 +O=C(C1CNc2ccccc2O1)N1CCCCCC1 +Cc1ccccc1-n1cnnc1SC(C)C(=O)N1CCCCC1 +Cc1ccc2c(c1O)CCNC2c1nn(C)c2ccccc12 +COCC(O)CN(C)C(=O)Cc1ccc(F)cc1 +O=C(NCCCC(=O)N1CCCC1)c1nc2ccccn2n1 +C=CCOc1ccccc1CN1CCOC(C(=O)OC)C1 +COC(=O)C(NC(=O)c1cccc2cn[nH]c12)c1ccc(F)cc1F +Cc1nc(C)c(CNC(=O)NCc2coc3ccccc23)s1 +COc1ccc(CC(=O)Nc2ccc(C)cc2OC)cc1F +Clc1ccc(-n2nnnc2SCc2nnc(C3CC3)o2)cc1 +N#CC(CCC(=O)NC1CCCCC1)c1ccco1 +O=C(C1COc2ccc(F)cc2C1)N1CCCC1c1ccncc1 +CC(NC(=O)NCc1cccc(NC(=O)C2CC2)c1)c1ccccc1 +Cc1ccc(S(=O)(=O)NCCC(=O)N(C)C(C)C)cc1C +N#Cc1ccc(OCC(=O)NCc2ccc3c(c2)OCO3)cc1 +CC(=O)N1CCN(c2c(N)cccc2Cl)CC1 +CC(C)NC(=O)CN1CCN(CC(=O)N(C)CC(F)(F)F)CC1 +CCC(C)NC(=O)c1cccc(S(=O)(=O)N(C)c2ccccc2)c1 +O=C(CSc1cccs1)NCc1ccccn1 +O=C(NCc1cccs1)c1ccc(S(=O)(=O)C2CCCC2)cc1 +Cc1nc(C(=O)Nc2cc(F)cc(S(N)(=O)=O)c2)cs1 +CCC(=O)N1CCCc2cc(NC(=O)c3ccc(F)cc3)ccc21 +Cc1nnc(C(C)N2CCN(S(N)(=O)=O)CC2)o1 +Cc1nc(COc2ccc(F)c(Cl)c2)oc1C +COc1sc(CN2CCOCC23CCC3)cc1Br +Cc1c(Cl)cccc1NC(=O)CSc1nn2cnnc2o1 +Cn1ccnc1C(NC(=O)c1cnccn1)c1cccc(F)c1 +NC(=O)c1cccc(OC(=O)C2CC3CCC2O3)c1 +COC(=O)Cc1csc(N(C)C(=O)C2CC=CC2)n1 +CCOc1cn(-c2ccc(F)cc2)nc1C(=O)N1CCN(C)CC1 +CCCNC(=O)CCc1nc(-c2cc3ccccc3[nH]c2=O)no1 +Cc1ccn(-c2ccccc2NCc2ccsc2)n1 +N#Cc1c(NC(=O)c2cc3ccccn3n2)sc2c1CCCC2 +COc1ccc(CNC(=O)c2cccc(OC)c2F)cn1 +O=C(C1CC1)N(CC1CCCO1)c1nc(-c2ccc(F)cc2)cs1 +COc1cc(C)c(C(=O)N2CCC(Cc3ccccc3)C2)cc1OC +COC(=O)Nc1ccc(NC(=O)N(C)Cc2ccncc2)cc1 +CS(=O)(=O)c1ccc(N2CC(CO)CC2=O)cc1 +COCCCOc1cccc(C(=O)Nc2ccc3c(c2)COC3)c1 +Cc1ccc(CC(=O)NCC(C)c2nc(-c3ccccc3)no2)cn1 +CS(=O)(=O)Nc1ccc(-c2ccc(S(C)(=O)=O)nn2)cc1 +CC(C)COC(C)C(=O)N1CCCC(C(N)=O)C1 +Cc1ccccc1OC(=O)C1CCN(c2ccc3nnnn3n2)CC1 +CCCCS(=O)(=O)N1CCN(C(=O)c2ccc(OC)cc2)CC1 +COc1ccc(C(C)=O)cc1S(=O)(=O)Nc1ccccc1 +CC(C)(CNC(=O)CCNC(=O)c1ccco1)N1CCOCC1 +Cc1ccccc1S(=O)(=O)N(CC(C)O)CC(C)O +COC(=O)c1ccc(Br)c(S(=O)(=O)N(C)C2CC2)c1 +Cc1ncsc1CCN(C)C(=O)c1ccc(Cn2cnnn2)cc1 +O=C(CCCN1CCOC1=O)NCCc1ccc(F)cc1F +Cn1ccnc(NC(=O)C2(c3cccc(Cl)c3)CCCC2)c1=O +CCN(C(=O)c1sc2ncn(C)c(=O)c2c1C)C1CCCC1 +C=CCn1c2c(ccc1=O)CC(NC(=O)c1ccsc1)CC2 +O=C(NCc1nnc2n1CCCCC2)c1cc(Cl)c[nH]1 +COc1cccc(C=Cc2ccc3cccc(O)c3n2)c1O +COC(=O)c1scc(-c2ccc(Cl)cc2)c1N +CN(Cc1ccc2ccccc2c1)C(=O)c1ccccn1 +COc1ccc(NC(=O)N2CCCCC2CO)cc1 +CC(O)CN1CCN(C(=O)c2ccc(Br)cc2)CC1 +Cn1c(=O)c(SCC(=O)NCc2cccs2)nc2cccnc21 +CC(C)(C)c1ncc(C(=O)N2CCN(C3CCCC3O)CC2)s1 +N#CC(C(=O)C1CCCN1Cc1ccccc1)c1ccc(F)cn1 +CCc1nc(CCNC(=O)COc2ccccc2)sc1C +CCn1cnnc1CNC(=O)NCc1cccc(OC)c1OC +CCc1nc2c3c(C)c(C)n(-c4cccc(OC)c4)c3ncn2n1 +Cc1cccc(C(C)C)c1NC(=O)C(C)Sc1nnc(C)n1N +Cc1cc(C(=O)N2CCN(c3ccccc3)CC2)c2c(C)nn(C)c2n1 +CCc1noc(CC)c1CNC(=O)NCC(=O)Nc1cccc(F)c1 +CC(C(N)=O)N1CCN(C(=O)c2c(Cl)cccc2Cl)CC1 +CSc1ccccc1C(=O)N1CCC2(CC1)OCCCO2 +Cc1ccc(-c2n[nH]c(NC(=O)c3ccc(=O)n(C)n3)n2)cc1 +Cc1cc(C)n(CCCNc2ccc3nnnn3n2)n1 +O=C(NCc1cnn2ccccc12)c1ccc2c(c1)OCO2 +CCC(C)NC(=O)Nc1ccc(-c2noc(-c3ccncc3)n2)cc1 +CCc1nnc2c(NCc3ccccc3OC)nc3ccccc3n12 +CC1CN(C(=O)c2ccc(Br)cc2O)CCO1 +O=S(=O)(C1CC1)N1CCC2(CC1)CC(Oc1ccccn1)CO2 +CC(CC#N)N(C)CCOc1cccc(Cl)c1 +O=C(c1cn2cccnc2n1)N1CCOC(c2ccccc2Cl)C1 +Cc1nnc(SCc2nc3c(oc4ccccc43)c(=O)[nH]2)s1 +CC(C)CC(NC(=O)c1cc2cccnn2c1)C(=O)N1CCCC1 +Nc1cnccc1SCC(=O)Nc1ccc(Br)cn1 +CC1CCC(OCC(=O)c2c(F)cccc2F)CC1 +CC(C)C(NC(=O)c1ccc(N(C)S(C)(=O)=O)cc1)C(C)C +Cc1ccc(-n2ncc3c(NCCO)ncnc32)c(C)c1 +CCCNC(=O)c1cc(Cl)c(OCC)c(OC)c1 +CCCCSc1nnc(C)n1Cc1ccccc1 +CCOc1cccc(-c2cnn(C)c(=O)c2C#N)c1 +Cc1c(Cl)cccc1NC(=O)NCC(O)COCC(C)C +CCc1n[nH]c(SCC(=O)N(C)CC(F)(F)F)n1 +Cn1cnc(CNC(=O)C2(c3ccccc3F)CC2)n1 +CC(C(=O)Nc1ccc(C#N)cc1)n1nnc(-c2ccccc2)n1 +CN(C(=O)NCCCn1cccn1)C1CCCCC1 +Cc1ccc(C)c(S(=O)(=O)NCCC(=O)NCC(C)C)c1 +COc1ccc(NC(C)=O)cc1NC(=O)Nc1cc(C)on1 +CC1CCCCN1C(=O)c1cnc(C2CC2)nc1N +CCOc1ccc(NC(=O)Oc2cccc3cccnc23)cc1 +Cc1cccc(CCC(=O)Nc2cccc(N)c2)c1 +CC(C)COc1ccccc1CN(C)C(=O)Cc1ccncc1 +CN(Cc1cccc2c1OC(C)(C)C2)CC(F)F +CC1(C)Cc2cccc(OCCNc3ccc4nnnn4n3)c2O1 +Cc1c(O)ccc2c1C(CNC(=O)c1ccccc1)NCC2 +CN(c1ccccc1C(N)=O)S(=O)(=O)c1ccc(C(N)=O)cc1 +O=C(NCCSc1ccccn1)c1ccc(-c2cc[nH]n2)cc1 +CC(=O)N1CCCN(C(=O)C2COc3ccccc3O2)CC1 +Cc1ccc(S(=O)(=O)N(C)C(C)c2ccncc2)s1 +O=C(NCCNC(=O)C1CCOc2ccccc21)c1ccc(F)cc1 +CC(C)OCc1cccc(S(=O)(=O)N2CCc3ccccc3C2)c1 +CCCCOc1ccc(-n2c(=O)[nH]c3ccccc3c2=O)cc1 +CCC1Nc2cc(F)c(F)cc2N(COC)C1=O +Cc1ccccc1CNC(=O)NCc1nccn1Cc1ccccc1 +CCC(NC(=O)Cc1ccc(C)nc1)c1cccs1 +O=C(c1scnc1C1CC1)N1CCCC(c2nnc3n2CCC3)C1 +Cc1ccc(CNC(=O)CN(c2ccccc2)S(C)(=O)=O)cc1 +c1cc(CN2CCC(c3ccnc4nccn34)C2)ccn1 +Nc1ccc2c(c1)N(C(=O)c1ccc(Br)cc1)CCS2 +C#CCNC(=O)NCc1ccc(OCC)c(OC)c1 +Cc1cc(Oc2ccc(NC(=O)Cc3noc4ccccc34)cc2)n[nH]1 +CC1COC(CO)CN1C(=O)C1CC1c1c(F)cccc1Cl +O=C(Cn1cnnn1)Nc1ccccc1OC1CCCC1 +Cc1ccc(CC(=O)NCC2COc3ccccc3O2)cc1 +Cc1cc(F)ccc1CCNC(=O)CNC(=O)Cc1ccccc1 +COc1ccc(C(=O)Nc2nc3[nH]c(C)cc(=O)n3n2)cc1OC +COCc1ccc(C(=O)NC2CC(=O)N(CC3CCCCC3)C2)o1 +CC(C)N(C1CCC1)S(=O)(=O)c1cccc(-n2cnnn2)c1 +COC(=O)c1cc(-c2ccc(Cl)c(C)c2)[nH]c1N +N#Cc1cc(-c2ccccc2F)cnc1N1CCOCC1 +O=C(c1ccnnc1)N1CCCCC1c1nc2ccccc2s1 +Cc1ccc(CNC(=O)CCNS(C)(=O)=O)s1 +CCOC(=O)Cn1c(=O)sc2cccc(Cl)c21 +CCCc1ncc(-c2csc(NCC(C)C)n2)s1 +O=C1CCc2c(OCCCS(=O)(=O)c3ccccc3)cccc21 +Clc1ccc(OCc2nn3c(-c4ccco4)nnc3s2)cc1 +Cc1noc(-c2cccnc2)c1C(=O)N(C)Cc1ccccc1 +O=C(CC1CN(Cc2ccccc2)CCO1)NCC1CCCCC1O +O=C(CNC(=O)Nc1cccc(C(=O)N2CCCC2)c1)NC1CC1 +Cc1nccn1-c1cncc(C2CCCN(Cc3ccccn3)C2)n1 +Cc1ccc(-n2nnc(C(=O)N3CCCCC3CCO)c2C)cc1 +Cc1nc2c(c(C(F)(F)F)n1)CC(C(=O)N1CCOCC1C)CC2 +CCC1CCCN(C(=O)c2cn(-c3ccc(C)cc3)nn2)C1 +CCn1ccc2cc(NC(=O)Cc3cccs3)ccc21 +COc1ccc(OCC(=O)Nc2ccccc2OC)cc1 +O=C(NCc1nc(-c2ccco2)n[nH]1)c1ccnc(OC2CCC2)c1 +c1coc(-c2nnc(CN3CCOc4ccccc43)o2)c1 +Cc1ccc(F)cc1NCC(=O)Nc1ccc(CC#N)cc1 +O=C(NCCc1csc(-n2cccn2)n1)c1ccc2[nH]cnc2c1 +Cn1c(SCC(=O)Nc2ccc(Br)cc2)n[nH]c1=O +O=C1CN(S(=O)(=O)CC2CCCCC2)CCN1 +C=CCCOC(C)C(=O)Nc1ccc2c(c1)OCCO2 +CCOC(=O)CSc1nnc(-c2ccccc2OC)o1 +CCOC(=O)c1c[nH]c2cc(Br)ccc12 +O=C(NCc1ccccn1)c1c(Cl)cccc1Cl +CCOC(=O)c1nnn(-c2cccc(C(=O)OC)c2)c1N +CCCNC(=O)N1CCN(Cc2ccc(OC)nc2)CC1 +O=C1CSc2ccc(C(=O)NC3CC4CC3C3CCCC43)cc2N1 +CC(c1cccc(O)c1)N(C)C(=O)NC1CCN(CC(F)(F)F)C1 +CCc1nc(CN2CCN(C(=O)c3sccc3CC)CC2)no1 +COc1cc(CCC(=O)N2CCNC(=O)C2)cc(OC)c1OC +N#CCCCOc1cccc(NCc2cc(F)ccc2F)c1 +CCNC(=O)CN1CCN(CCS(=O)c2ccccc2)CC1 +COC(=O)C1=C(C)C(C(=O)c2cc3ccccc3o2)=NC1C +NC(=O)Cn1c(-c2ccc(Br)cc2)nc2ccccc21 +COC(=O)C1CN(CCc2c[nH]c3ccccc23)CCC1=O +O=C(c1cn2cccnc2n1)N1CCCC1c1ccc2c(c1)OCO2 +Cc1nn(C)c2ncc(NC(=O)N(C3CC3)C(C)C3CC3)cc12 +CC(C(=O)Nc1cc(Cl)ccc1N)n1cc(Br)cn1 +CCOC(CC)C(=O)NC(C)c1ccc(OC)c(F)c1 +CC(C)CN1CC2CN(S(=O)(=O)c3cn(C)cn3)CC2C1=O +OCCc1cn(-c2c(Cl)cc(Br)cc2Cl)nn1 +CC1CCC(C(N)=O)CN1C(=O)Cc1c(F)cccc1F +CNC(=O)Cc1ccc(NC(=O)CCc2ccccc2Cl)cc1 +Cc1nn(C)c2nc(NCC3CC(=O)N(C4CC4)C3)sc12 +Cn1cc(CNc2ncccn2)c(C2CCCCC2)n1 +O=C(CC1C=CCC1)N(Cc1ccncc1)C1CC1 +Cc1c(Br)cccc1NC(=O)NC(C)CCCO +CC(C)C(=O)NCCNC(=O)c1cnn(-c2ccc(F)cc2)n1 +CCCSc1nnc2[nH]c(=O)c3c(n12)CCCC3 +Cc1ccccc1NC(=O)Cc1nc(-c2ccc(O)cc2O)cs1 +Cc1[nH]c(C(=O)NC2CC2)c(C)c1S(=O)(=O)N1CCCCCC1 +CC(=O)OC(C(=O)N1CCN=C1c1ccccc1)c1ccccc1 +O=C(NCCc1c[nH]c2ccc(F)cc12)N1CCOCC1C1CC1 +Cc1cc(C)n(Cc2ccc(C(=O)NCCC3=CCCCC3)o2)n1 +CCCNC(=O)N1CCC(C(=O)Nc2nncs2)CC1 +CCN(CC)C(=O)CCCNC(=O)Nc1ccc2nc(C)sc2c1 +CCCN1CCc2c(sc3c2c(NCCCO)nc2nnnn23)C1 +CC1(C)CC1(C(=O)NCc1n[nH]c2c1CCC2)c1ccc(F)cc1 +Cn1c(C(=O)Nc2cc(Cl)c(O)c(Cl)c2)cccc1=O +CC(C)C(=O)NCCNC(=O)c1cccc(Cl)c1Cl +CCOC(=O)c1ccc(N2CCN(CC(C)C)C(=O)C2C)nc1 +C#CCOC(=O)CCc1c(C)nc2c3ccccc3nn2c1C +CCOc1ccc(NC(=O)CCc2ccccc2N)cc1 +CCC(O)CN1CCN(CC(F)(F)C(F)F)CC1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)Cc1ccccc1F +CC(C)CNC(=O)N1CCCC(C(=O)Nc2ccc3[nH]ncc3c2)C1 +CC(CNC(=O)CNC(=O)c1ccccc1)c1ccsc1 +O=C(NCC1CCCCO1)c1c[nH]c2ccccc12 +Cc1cc(C)c(S(=O)(=O)N2CCC(=O)C2)c(C)c1 +FC(F)n1ccc(-c2nc3c4ccccc4ncn3n2)n1 +Cc1occc1C(=O)NCc1ccc(OCC(F)(F)F)cc1 +Cc1nn(C)c(C)c1C1CCCN1C(=O)c1ccccc1-n1cccn1 +CC1CC1C(=O)Nc1ccc(S(C)(=O)=O)cc1 +CCN(CC(=O)OC)C(=O)CCc1ccc(F)cc1 +CCc1nc(NC(=O)COc2ccccc2OC)sc1C +Cc1ccc(C)c(-c2nnc(NC(=O)C(C)C)o2)c1 +Cn1cc(CCNC(=O)c2sc3ccccc3c2Cl)cn1 +CC(C)CC1CNC(c2ccccc2)CN1C(=O)N(C)C +O=C(COc1ccc(F)c(F)c1)Nc1ccc2c(c1)OCCCO2 +COc1ccccc1CCN(C)Cc1ccc(C(=O)N(C)C)[nH]1 +CCC(C)NC(=O)CCNC(=O)Cc1cccc(O)c1 +O=c1c(NCc2ccccc2)nccn1-c1ccc(F)c(Cl)c1 +Cc1ccccc1CN1c2ccc(S(N)(=O)=O)cc2CC1C +CC(C)(C)c1cn(C2CCN(C(=O)CN3CCCCC3=O)CC2)nn1 +CCS(=O)(=O)c1ccc(NC(=O)c2ccc(Cl)cc2)cc1 +CC(C)C(=O)NCc1nnc2c(C(F)(F)F)cc(Cl)cn12 +O=C(Cc1ccccc1F)N1CCCC1c1ccc[nH]1 +CC(NS(C)(=O)=O)C(=O)NC(c1ccccc1)c1ccco1 +CC(C)N(C)C(=O)C1CCCN(C(=O)c2ccncc2F)C1 +CCOc1cc(NC(c2nccc(C)n2)C2CC2)ncn1 +CCC(C)N(CC(=O)Nc1cccc(C)c1C)C(=O)C1CCOC1 +O=c1c2nnn(Cc3ccccc3)c2ncn1-c1ccccc1 +COCCn1c(-c2ccc(C)c(C)c2)ccc(CO)c1=O +O=c1cc(C2CCC2)ncn1Cc1nc(-c2cccc(Cl)c2)no1 +Cc1nc2cc3c(cc2n1Cc1cccc(N)c1)OCCO3 +Cc1ccc(NC(=O)CSc2nnc(C)n2-c2ccccc2)cc1 +O=C(Nc1nc2c(F)cccc2s1)c1cc2ccccc2oc1=O +CSc1ccc(CN(C)C(=O)COc2ccc(F)cc2)cc1 +O=C1NC(c2cc(Cl)c3c(c2)OCCCO3)Nc2ccccc21 +CCc1nc(CCNC(=O)N(C)CC2CCCO2)cs1 +COc1ccc(Cl)cc1NC(=O)Nc1ccc(CC(N)=O)cc1 +Cc1cc(C)c(O)c(C(=O)N(C)CCNC(=O)C(C)C)c1 +COC(=O)c1ccccc1NC(=O)CSc1nnc(C(C)C)o1 +CCC(=O)Nc1ccc(NC(=O)c2ccc(Cl)cc2)nc1 +Cc1cc(CNc2ncc(C(N)=O)cc2Cl)no1 +Cc1ccccc1CNC(=O)Nc1ccc2c(c1)NC(=O)CC2 +COCCN(C)C(=O)Nc1ccc(=O)n(CCOC)c1 +Cc1ccccc1NC(=O)Nc1ccc(-n2ncnn2)cc1 +CS(=O)(=O)N1CCCC1c1ccc(Cl)c(N)c1 +COc1ccc(OC)c(-c2c(C(F)(F)F)nn(C)c2N)c1 +Cn1nc2n(c1=O)CCN(Cc1cc(F)ccc1C#N)C2 +CC(=O)Nc1cc(NC(=O)NCc2ccc(C)c(F)c2)ccc1C +CNC(=O)c1cc(-c2ccccn2)nc2ccccc12 +COc1ccc(C(=O)Nc2cc(C)on2)cc1OC +O=C(c1ccc(OCC2CC2)cc1)N1CCOCC1C1CC1 +CSc1ccccc1C(=O)Nc1nc(-c2ccccn2)cs1 +Cc1ccc(S(=O)(=O)N(CCC#N)C2CC2)c(C)c1 +Oc1ccc(Nc2ncnc3c2cnn3Cc2ccccc2)cc1 +COC(=O)C(C)(C)NC(=O)c1ccc(F)cc1Cl +Cn1cc(C(=O)Nc2ccc(C(C)(C)C)cc2)c(=O)c2cccn21 +CCOc1ccccc1-n1nnnc1SCC +Cc1cc(C(C)NC(=O)Cc2cn3cccc(C)c3n2)c(C)s1 +CNS(=O)(=O)CCCSc1nnnn1-c1ccc(C)cc1 +CCCNC(=O)CNC(=O)Nc1ccc(C)cc1Cl +CC(=O)Nc1ccc(NC(=O)Nc2cc(C)on2)cc1Cl +CC(C)c1noc(C(C)N2CCN(CC(=O)NC3CCCC3)CC2)n1 +CCN(C(=O)NCc1ccc(C(=O)N(C)C)cc1)C1CCCCC1 +CCc1noc(C)c1C(=O)Nc1ccccc1C(=O)NC1CC1 +CCn1c(CSc2nnc(C)c(C)c2C#N)nc2c(F)cccc21 +Cc1cccc(C(=O)NC2CCCC2C)c1NC(=O)c1ccncc1 +Cc1ccc(CCNC(=O)c2cnc3c(C)cccn3c2=O)cc1 +Cc1cccc(C)c1OC1CN(C(=O)Cc2cccc(O)c2)C1 +OCCN(Cc1ccno1)Cc1ccccc1Br +O=c1oc(-c2cccs2)nn1Cc1cc(-c2ccco2)on1 +Cc1ccc(C#N)c(=O)n1CCOc1cccc(N)c1 +CC(NC(=O)C1CC1c1ccccc1F)c1ccc(-n2ccnc2)cc1 +COc1ncnc2c1CN(c1nn3cc(C(C)(C)C)nc3s1)CC2 +O=C(Nc1ccc(F)cc1)c1cc(Cl)c2c(c1)OCO2 +COc1cc(CNc2ccn(C)n2)ccc1OCC(C)C +CCn1ccc2c(cc(C(=O)Nc3cccc(F)c3)n2C)c1=O +Cc1cc(NC(=O)NCCCSc2nc3ccccc3s2)no1 +O=C(Nc1ccncc1)c1ccc2nc(-n3cccc3)sc2c1 +CCOC(=O)N1CCCC(C(=O)Nc2cccc(-n3cnnc3)c2)C1 +Cc1cccc(-n2nnc(-c3cccs3)c2N)c1C +O=C(C1CCCCC1)N1CCc2[nH]c(=O)ccc2C1 +CCCOc1ccc(C(=O)N2CCC(C)CC2)cc1 +Cc1cccc(N(C)C(=O)c2ccc(N3CCNC3=O)cc2)c1 +COc1ccc(NC(=O)CNc2ccc(C(=O)NC(C)C)cc2)cc1 +COc1cccc(C(=O)N(CC2CCCO2)c2ccncc2)c1F +CCOC(=O)c1nn(-c2c(F)cccc2F)c(N)c1C#N +CC(NC(=O)c1cccc(Cl)c1)c1nc2ccccc2n1C +CC(C)c1cc(C(=O)NC2CC2)nc2cc(-c3ccccn3)nn12 +COCCNC(=O)CNc1ncnc2sc(-c3ccccc3)cc12 +CCNC(=O)CN(CC)C(=O)C1CCN(C(=O)c2ccoc2)CC1 +OCCc1cnc2c(-c3nc(C4CCOC4)n[nH]3)cnn2c1 +CCCNC(=O)c1cn2ccnc(-c3ccccc3)c2n1 +CCOCCCNC(=O)C1CC(=O)N(c2ccccc2)C1 +CCN(CC)C(=O)c1c(C)nc(N)nc1-c1cccs1 +O=C(CCC1CCCCC1)N(CCO)Cc1ccccc1 +COc1ccc(NC(=O)c2ccc3c(c2)OCCCO3)c(OC)c1 +CCCCOc1cccc(-c2cnn(C)c(=O)c2CO)c1 +CCCN(Cc1ccc(C#N)cc1)C(=O)Cn1c(=O)[nH]c2ccccc21 +C#CCOc1cccc(NC(=O)Cc2cccc(OCC#N)c2)c1 +Cc1cc(-n2nc(C)cc2C)nc(-c2ccccc2O)n1 +Oc1cccc(C2CN(Cc3ccco3)CCO2)c1 +CCCCN(CC)C(=O)C1CSc2ncc(C)c(=O)n2C1 +CC(C)c1nc(CC(=O)Nc2cc[nH]n2)cs1 +Cc1nc(NC(=O)c2sc(-n3cccc3)nc2C)sc1C +CCOc1cc(CNc2cnn(CC)c2)ccc1O +CCCOc1c(Cl)cc(C(=O)NC)cc1OC +CN(CC(C)(CO)CO)C(=O)C1CC1c1c(F)cccc1Cl +CC(C)COCC(O)CNC(=O)Nc1cc(Cl)cc(Cl)c1 +CC(=O)Nc1nc2c(s1)CN(CC(=O)c1ccc(Cl)cc1)CC2 +CC(C)(C)OC(=O)NCCCC(=O)N1CCOC(C)(C)C1 +CCOc1ccc(CNc2ccccc2OC)cc1OC +CCn1nc(C)c(CNC(=O)c2cccc(-c3nnnn3C)c2)c1C +O=C(NCc1cccs1)c1nc(-c2ccccc2)no1 +CC(Sc1nc(N)cc(N)n1)C(=O)NC1CCCC1 +CSc1ccccc1C(=O)NC(C)c1ccc(-n2ccnc2)cc1 +CCc1cnc(C)nc1NC(C)Cc1cc(C)n[nH]1 +CN(C)C(=O)N1CC2CCC(C1)N(C(=O)c1cnn3ccccc13)C2 +COCCNC(=O)Nc1cc(-c2cccc(Cl)c2)nn1CCO +COc1cc2c(cc1OC)C(c1ccccc1)N(CC(O)CO)CC2 +O=C(Cc1cccs1)Nc1ccc(N2CCCC2=O)cc1 +Cc1csc(CCNC(=O)c2cc(Br)cnc2N)n1 +CN(Cc1nc2ccccc2s1)C(=O)COC1CCCCC1 +CCc1ccc(OCC(=O)NCC2CN3CCCCC3CO2)cc1 +Cc1nc(C(c2cccnc2)N2CCOCC2)n(Cc2ccccc2)n1 +CCOC(=O)c1cccc(Cn2c(C)ccc(C#N)c2=O)c1 +CN(Cc1ccco1)C(=O)CSc1nnc(-c2ccccc2)n1C +CC(C)c1ccc2c(c1)S(=O)(=O)N=C(NCc1ccccc1)N2 +COc1ccc(-c2nc(C(=O)NCCO)cs2)cc1 +CC(=O)c1cccc(S(=O)(=O)N(C)Cc2sccc2C)c1 +NC(=O)c1cccc(NC(=O)NCCC(=O)NC2CCCC2)c1 +O=C(Cn1cnc2ccccc21)Nc1ccccc1O +CC(NC(=O)c1cc(F)ccc1Br)C(=O)NC(C)(C)C +CCc1nc(CC2CN(c3ncnc4oc(C)nc34)CCO2)no1 +COc1ccc(CCNC(=O)c2cc(C)c(C)s2)cc1OC +O=C(Cc1ccccc1)Nc1nc(-c2cccnc2)cs1 +COCCCNC(=O)c1cn2c3c(cccc3c1=O)CC2C +Cc1cc(N)nc(SCC(=O)Nc2ccc(C)c(F)c2)n1 +COC(=O)C1CCc2c([nH]c(=O)n2CC(F)(F)F)C1 +COc1ccc(C(C)Nc2c(C)nn(C)c2C)cc1 +COc1cccc(OCC(=O)Nc2nc(C)no2)c1 +COC(=O)c1cc(-c2ccc3c(c2)OCCO3)nn1-c1ccccn1 +Cc1cc(C)c2c(n1)sc1c(=O)n(CC(=O)OCC(N)=O)cnc12 +COC(=O)C(C)CN(C)C(=O)c1cc(Br)cn1C +OC(CNCc1cccc(Cl)c1)c1ccccc1 +O=C(CC1COC(=O)C1)Nc1c[nH]cc(Br)c1=O +CN1CCc2c(c3cc(F)ccc3n2C=Cc2cccnc2)C1 +c1ccc2c(c1)CN(Cc1cnc3ncccn13)Cc1ccccc1-2 +CC(Sc1ccccn1)C(=O)Nc1ccc2c(c1)COC2 +O=C(NCc1ccc2c(c1)OCO2)c1cc2ncccn2n1 +O=C(Nc1nc(=O)n(C(=O)c2cccs2)s1)c1ccccc1 +COc1cccc(C2CCCCN2C(=O)c2nc(C)c[nH]2)c1 +CC(C)c1cc(C(=O)Nc2sccc2C#N)nn1C(C)(C)C +Cc1ccn2ncc(C(=O)N3CCCCC3Cn3cccn3)c2n1 +CCCCCNC(=O)Cn1cnc2sc(C)cc2c1=O +COC(=O)c1c(CC(=O)N2CCCCC2C)[nH]c(C(C)=O)c1C +CCCCN(C(=O)c1cc(OC)ccc1Br)C1CC1 +CC(=O)Nc1ccc(Cl)c(C(=O)N(C)C(CO)C(C)(C)C)c1 +O=S(=O)(Nc1cc(F)cc(F)c1)c1cccs1 +CCCOc1ccccc1C1Nc2ccccc2C(=O)N1CCOC +COC(=O)C1CCN(C(=O)c2ccc(Cl)c(N)c2)CC1 +Cc1cc(NC(=O)NCCC(O)(c2nccn2C)C(F)(F)F)no1 +Cc1c(-c2ccccc2)nn2c(N)c3c(nc12)CCC3 +CC(=O)c1ccc(OC(=O)COc2cccc(C)c2)cc1 +COc1ccccc1CN(C)S(=O)(=O)N(C)C1CCCCC1 +COCC1CCCN1C(=O)COc1c(C)ccc(C)c1C +CCOc1ccccc1-c1nnc(CS(=O)(=O)c2ccccc2)o1 +Cc1nc(C)c(CNC(C)c2cccc(C(F)(F)F)c2)s1 +CC(=O)Nc1ccc(NC(=O)c2nnn(-c3ccccc3)c2N)cc1 +O=C(Nc1ccc(C(F)(F)F)cc1)Nc1nc[nH]n1 +CCc1cccc(C)c1NC(=O)c1nc2ccccc2s1 +Cc1cc(Cl)ccc1OCc1nnnn1C1CC1 +NC(=O)NC(CC(=O)Nc1ccc(OC(F)F)cc1)c1ccccc1 +N#Cc1ccc(NC(=O)CCCOc2ccccc2F)cc1 +CC=C(C)CN1CCOC(CCNC(=O)C(C)(C)C)C1 +O=C(CNC(=O)C1CC1)Nc1ccc(F)c(F)c1F +N#CCn1ccc(NC(=O)c2ccn(C3CCCC3)n2)n1 +Cc1nc(CNc2cc(C(F)(F)F)cc(C(F)(F)F)c2)no1 +O=C(Oc1ccc(Cl)c(Cl)c1)C1CCCN1C(=O)C1CC1 +COC(=O)c1cnn2c1ncc1c(=O)n(-c3ccc(C)cc3)ccc12 +COCCCNC(=O)c1cn(CC(=O)N(C)C)nn1 +CC(C)c1cc(-c2nnc3sc(-c4ccsc4)nn23)n(C)n1 +CCOCCS(=O)(=O)N1CCc2cc(F)ccc2C1 +COc1ccccc1C(NC(=O)C1CCCO1)c1ccccn1 +CNC(=O)c1ccc(OC)c(NC(=O)C(C)OC)c1 +COCCN(Cc1cccnc1)C(=O)c1c[nH]c2cccc(F)c12 +CC(C)c1ccc(NC(=O)Nc2cnn(CC3CCCO3)c2)cc1 +CN(Cc1ccc2c(c1)OCO2)C(=O)CCCNC(=O)c1ccco1 +CC(=O)Nc1cc(NC(=O)c2cc(C)ccc2C)ccc1C +O=C(NCCCn1cnc2ccccc21)C1CC=CCC1 +OCc1cc2c(cc1OCC1CCOC1)OCO2 +CCc1ccc(C(C)NC(=O)CSc2nc(N)cc(=O)[nH]2)cc1 +COCCNC(=O)Cn1c(COC)nc2c(N)cccc21 +COc1ccc(C)cc1C(C)NC(=O)c1cnc2n(c1=O)CCS2 +CCc1c(C)nc(-c2cc(Cl)c3c(c2)OCCO3)[nH]c1=O +CCn1cc(C(=O)Nc2ccc(Oc3ccc(Cl)cc3)nc2)cn1 +Cc1nccn1-c1ccc(C(C)NC(=O)Nc2cnn(C)c2)cc1 +O=C(c1cc(S(=O)(=O)N2CCCC2)c[nH]1)N1CCCC1 +Cc1nc2ccc(NC(=O)C3CC(=O)N(Cc4ccco4)C3)cc2o1 +c1ccn2c(SCc3cn4ccsc4n3)nnc2c1 +CCCCNC(=O)NCCNC(=O)c1ccoc1 +Cc1cccc(NC(=O)c2ccc(-n3cncn3)nc2)c1 +Cc1n[nH]c2ncc(NC(=O)c3scnc3C3CC3)cc12 +CCc1noc(CN(C)c2cccc3ccccc23)n1 +CC(C)OCc1cccc(CNC(=O)c2ccc(=O)[nH]c2)c1 +COc1cccc(CC(=O)Nc2cccn3nc(C4CC4)nc23)c1 +Cc1noc(NC(=O)CCc2cccc(Cl)c2Cl)n1 +Cn1nnnc1SCC(=O)N(c1ccccc1)c1ccccc1 +COc1cc2c(c(OC)c1OC)C(c1ccoc1)NCC2 +CC1COCCN1C(=O)NCc1nc2ccccc2s1 +CC1COCCN1Cc1nc2ccccc2n(C)c1=O +COc1ccc(C(O)C(C)NC(=O)C(C)(C)c2cccs2)cc1 +O=C(Nc1ccc(Cl)c(Cl)c1)OCCOCCO +O=C(NC1CCCN(c2ccccc2F)C1=O)C1CC=CC1 +CNC(=O)c1cnn2c(C(F)(F)F)cc(C(F)(F)F)nc12 +Cc1cc2[nH]c(=O)cc(CSc3nccc(-c4ccco4)n3)n2n1 +CC(C)Oc1ccc(CNC(=O)c2c[nH]c3ccccc3c2=O)cc1 +CC(C)NC(=O)c1cnc(-c2ccccc2)nc1N1CCCCC1C +CC(C)n1nccc1NC(=O)CCC1CCCCC1 +Cc1ccc(CCC(=O)N2CCOC(C)(C)C2)c(C)c1 +CC(=O)N(c1ccc(C)cc1)S(=O)(=O)c1ccc(C)cc1 +O=C(NCC(F)(F)F)c1ccccc1NCCCO +CCNS(=O)(=O)c1c(C)nn(C(C)(C)C)c1N +CCCS(=O)(=O)NCc1ccc(C)cc1OC(C)(C)C +O=C(Nc1ccc(F)cc1)N1CCOC(c2ccccc2)C1 +O=C(CCn1c(=O)[nH]c2ccccc2c1=O)NCc1ccccn1 +Cc1cc(C(=O)CSc2nnnn2C)c(C)n1Cc1ccco1 +O=C(c1c(F)cccc1F)n1nnc2ccccc21 +Cc1ccc(-c2nc(-c3ccc4nncn4c3)no2)c(C)c1 +CCc1cccc(C)c1NCC(O)c1ccc(OC)c(F)c1 +CSc1ccc(C(=O)C2CCCN(C(=O)COC(C)C)C2)cc1 +Cc1ccc(NC(=O)CC(C)(C)C)cc1S(C)(=O)=O +CC(C)CC(=O)N1CCc2cc(C(=O)C(C)N)ccc21 +CC1CC(C)CN(c2nc3nccc(-c4ccncc4)c3c(=O)[nH]2)C1 +COc1ccc(C)cc1NC(=O)COC(=O)Cc1ccc(F)cc1 +COCc1nc2ccccc2n1CCOc1cccc(OC)c1 +CC(C)NS(=O)(=O)Cc1ccc(CNC(=O)c2ccccc2)cc1 +COc1ccc(C(C)(C)C(=O)NCCc2cccc(C(N)=O)c2)cc1 +Nc1cccc(CS(=O)(=O)NC2CCCCC2)c1 +CCOC(=O)C(NCC1CC1)c1c(F)cccc1F +CC(=O)Nc1cccc(C2NCCc3cc(C)cc(C)c32)c1 +CC(C)(NC(=O)Nc1ccc2c(c1)C(=O)NCC2)c1cccc(F)c1 +Cc1cc2oc(C(=O)c3ccccc3)c(N)c2s1 +Cc1cc(C(=O)NCc2ccccn2)nc(N2CCCCC2)n1 +COCCN(CC(C)C)S(=O)(=O)c1ccc(F)c(F)c1 +CC(C)(C)c1cc(NC(=O)c2cccnc2Oc2cccnc2)[nH]n1 +C=CCOC(=O)COc1ccc2c(=O)c(Cl)coc2c1C +CCc1c(C)sc(NC(=O)c2ccco2)c1C(=O)N1CCOCC1 +CNc1cc(C(=O)N2CCC(C)(O)C(C)C2)ccn1 +O=C(NCC(=O)N1CCCC1)NC1CCSc2c(F)cccc21 +COc1ccc(C(C)C)cc1-c1cc(CO)c(=O)n(C)n1 +CC(C)CCC(=O)Nc1ccc(F)c(S(=O)(=O)NC2CC2)c1 +COC(=O)CCN(CC(C)C)C(=O)c1ccc2c(c1)CCN2C(C)=O +CC(CC(O)c1ccco1)NC(=O)Nc1ccc2c(c1)C(=O)CCC2 +Nc1ccc(-n2nnc(-c3ccccc3)n2)c(Cl)c1 +Cc1ccn(C(C)C(=O)Nc2cnn(C)c2C(N)=O)n1 +CC(C)OCC(=O)Nc1c(N)cc(Cl)cc1Cl +CC(C)C(=O)NCc1nc(-c2ccc(OC(F)(F)F)cc2)no1 +O=C(NC1CC2CC1N(C(=O)CCc1ccccc1)C2)c1cccnc1 +COc1ccc(C)cc1C(O)CNCc1ccco1 +COc1ccc(OCC(=O)Oc2cccc(C)c2)cc1 +Cc1n[nH]cc1CNC(=O)c1c(F)c(F)c(F)c(F)c1F +Cc1cccnc1NC(=O)c1cc(F)ccc1Br +Cc1cccc(C2(NCC(=O)NCc3cccnc3)CCCC2)c1 +CNc1nc(-c2ccc(OC)c(Cl)c2)ccc1C#N +CCc1noc(CC)c1CC(=O)NC(C)C(C)(C)C +Cc1nnc(SCCC(=O)NCc2ccccc2)s1 +CCOC(=O)c1sc2ncn(CC(=O)C(C)(C)C)c(=O)c2c1C +N#CCCCCS(=O)(=O)N1CCCc2cc(F)ccc21 +O=c1c(=Cc2ccccc2)sc2nc(-c3ccco3)nn12 +COC(=O)CNC(=O)CC(NC(C)=O)c1ccccc1 +CC(CO)NS(=O)(=O)c1ccc(C(C)C)cc1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCCCn1cncn1 +Cc1cc(C)n(-c2ccc(NC(=O)NCc3cccnc3)cc2F)n1 +CC(C)(CNC(=O)N1CCCC1C(=O)NC1CC1)c1ccncc1 +Cc1cc(C(=O)N(C)CCOCC2CC2)ccc1S(N)(=O)=O +CC(OCCC(=O)Nc1cccc(N)c1)c1ccccc1 +NC(=O)Cc1ccccc1NC(=O)c1c[nH]c2cccc(F)c12 +COC(=O)C1(NC(=O)C(C)NC(N)=O)CCCC1 +CCc1cnc(CN(C)C(=O)Cc2c(CC)noc2CC)s1 +Cc1ccccc1CNc1ccc(C(=O)Nc2nncs2)cn1 +Cc1cc(NC(=O)CNC(=O)c2ccsc2)[nH]n1 +O=C(NCc1cccc(Cl)c1)N1CCOCC1C1CC1 +Cc1ccccc1-c1noc2ncnc(NCCN3CCOCC3)c12 +CCCOC(=O)C(C)NS(=O)(=O)c1ccccc1 +Fc1cccc(-n2cc(-c3noc(C4CCCC4)n3)nn2)c1 +CCC(=O)N1CCC(NC(=O)NCc2ccnc(OC3CCC3)c2)C1 +Cc1cc(C)n(-c2ccc(CN3CCn4c(nn(C)c4=O)C3)cc2)n1 +CN(C)C(=O)c1ccc(CSc2nncn2-c2ccccc2)cc1 +CCOc1ccc2c(c1)CN(C(=O)C1CC1C)CC2 +CC1c2cccn2CCN1C(=O)CCN1CCOCC1 +COc1ccc(F)cc1C(=O)N(CCC(N)=O)c1cccc(C)c1 +COc1ccc(CNn2c(C)nc3ccccc3c2=O)cc1OC +CCNC(=O)CNC(=O)Nc1cccc(Cl)c1SC(F)F +CCCNC(=O)CNC(=O)c1cc(S(C)(=O)=O)ccc1Cl +Cc1cccc(NC(=O)CCSc2nn3cnnc3s2)c1 +COc1cc(OC)c(CNC(=O)NC(C)C(C)C)c(OC)c1 +CCNC(=O)CNC(=O)c1ccccc1SCc1cc(C)no1 +CCN1CCN(C(=O)c2csc(C)n2)c2ccccc21 +C#CCNC(=O)N1CCN(S(=O)(=O)c2cccc(C)c2)CC1 +Cc1cc(NC(=O)COC(=O)C2(c3cccc(F)c3)CCCC2)no1 +COCc1cc(OCC#N)nc(-c2ccncc2)n1 +COc1ccc(OC)c(Cn2nnnc2C(C)(C)C)c1 +Nc1cnc2nc(-c3cccc(Br)c3)[nH]c2c1 +O=C(Cc1ccc[nH]1)N1CCN(c2ncc(Cl)cc2Cl)CC1 +CCCn1cc(-c2ccn(CC(=O)Nc3cc(C)nn3C)n2)c(C)n1 +COc1ccc(C2=C(C)C(N3CCN(C)CC3)=NS2(=O)=O)cc1 +CCN1CCN(C(=O)c2cnc3ccccc3c2C(F)(F)F)CC1 +CN(C)C(=O)CCNC(=O)N1CCN(c2ccccc2Cl)CC1 +CCCC(CNC(=O)C1CC=CC1)NC(=O)C1CC=CC1 +CN(CC(=O)Nc1ccccn1)C(=O)c1ccsc1 +CC(C)C(=O)Nc1cccc(NCc2cccc3c2OCCCO3)c1 +O=S(=O)(NC1CC1c1ccc(F)cc1)N1CCc2ccccc2C1 +CCOc1ccccc1-n1nnc(CO)c1C1CCC1 +Cc1ccc(-n2nnnc2SCC(=O)NC(C)C(C)C)cc1C +Cc1c(C(=O)Nc2cc(Cl)c(Cl)cn2)cnn1-c1ccncc1 +CN(C(=O)Nc1ccccc1OCCC(N)=O)C1CCCCCC1 +Cn1cc(Cc2nc(-c3ccncc3)no2)c2ccccc21 +Cc1cc(SCC(=O)NCc2ccccn2)nc2ccccc12 +Cc1cc2c(-c3ccccc3Cl)nc(=O)[nH]c2s1 +CCNc1ncc(C(=O)NCc2nc(-c3cccs3)n[nH]2)s1 +COC(=O)c1cccc(OC(=O)c2cnc(C)cn2)c1 +O=C(NCCc1ccccc1)NCc1ncc(-c2ccccc2)o1 +CCOC(=O)C1CCCN(c2ncnc(N)c2N)C1 +CN1CCOC(CNCc2ccccc2OCc2cccnc2)C1 +CCCn1c(=O)c(=O)[nH]c2cc(-c3noc(CNC(C)=O)n3)ccc21 +CN(C)S(=O)(=O)c1cccc(NC(=O)Cc2ccc(F)cc2)c1 +O=C(c1ccc2cc[nH]c2c1)N1CCN(C2CCCC2O)CC1 +CC(C)N(C(=O)c1ccco1)c1nnc(-c2cccnc2)s1 +Cc1nn(CC(=O)NCC2CCCO2)c(=O)c2cc3occc3n12 +O=C(NCc1ccc(F)cc1)c1cccn2c(=O)[nH]nc12 +CC(C(=O)NCc1ccc(-n2cncn2)nc1)n1cnc2ccccc21 +CC(NC(=O)Cn1c(=O)[nH]c2ccccc21)c1cc2ccccc2o1 +COC(=O)c1ccc(N)c(Oc2ccc(F)cc2)c1 +CN(Cc1nc2ccccc2n1C)C(=O)c1cccc(CC#N)c1 +CCC1=C(C(=O)OC(C)C)C(c2ccc(OC)c(OC)c2)NC(=O)N1 +O=C1c2ccccc2C2(c3ccccc3)NCCN12 +Cn1cc(CCC(=O)N2CCOCC2)c(-c2ccccc2)n1 +CC(c1cncs1)N(C)C(=O)c1cc(=O)[nH]c2ccccc12 +Cc1ccc(Cn2cnc3sc(C)cc3c2=O)cc1 +Cc1noc(CN2CCN(S(=O)(=O)N3CCCC3)CC2)n1 +Cc1ccc(S(=O)(=O)Nc2ccc(N)cc2Br)cc1 +Cc1ccc(CN2CCc3nnc(COc4ccccn4)n3CC2)o1 +Cc1nn(Cc2ccc(C#N)cc2)c(C)c1Br +CCN1CCN(C(=O)c2cnc3cc(C(C)=O)[nH]c3c2)CC1 +Cn1cc(SCC(=O)c2cc(Cl)ccc2Cl)cn1 +CC(C)N(C(=O)c1cc(NC(=O)C2CCCC2)c(=O)n(C)c1)C(C)C +CN(C)C(=O)COc1ccc(NC(=O)c2cc(Cl)ccc2O)cc1 +O=C(Nc1nc2c(s1)CCCCC2)c1ccc(-n2cncn2)cc1 +COc1cc(NC(=O)CSc2nnc(C)n2N)ccc1Cl +Cc1cccc(NC(=O)CCNC(=O)C(C)(C)C#N)n1 +CCn1c(C(=O)N2CCCCC2)cc2c(=O)oc3ccccc3c21 +CC1Cc2ccccc2N1C(=O)c1cc2c([nH]c1=O)CCCC2=O +Cc1cccc(OCCNC(=O)C(C)Sc2nnc(C)s2)c1 +c1ccc(CCNCc2c[nH]nc2-c2ccc3c(c2)OCO3)nc1 +Cc1ccc(NC(=O)CCCS(=O)(=O)c2ccc(F)cc2)cc1 +CCN(C(=O)c1ccc(=O)n(C)c1)C(C)c1cc2ccccc2o1 +CCOC(=O)CN(C(=O)c1ccc(O)cc1)C1CC1 +CC(C)C(=O)NCCNC(=O)CN1CCCCCC1=O +O=C(CNC(=O)c1[nH]nc2c1COCC2)Nc1ccc(F)cc1 +COC(=O)Cn1cc(NC(=O)CC(F)(F)F)cn1 +C=CCN(Cc1cccc(C#N)c1)Cc1cc(C(N)=O)cs1 +COC(=O)c1ccc(CSc2nncs2)cc1 +CCN(Cc1cccs1)C(=O)c1cn2cccnc2n1 +O=C(NCc1nnc2n1CCC2)Nc1cccc(C(F)(F)F)c1 +O=C(Nc1ccc(Cc2ccncc2)cc1)C1CCCO1 +CC(Sc1nnc(-c2ccccc2Cl)n1N)C(=O)NC1CC1 +FC(F)(F)c1cccc(C2(CNCc3cc[nH]c3)CCOCC2)c1 +Cc1c(NC(=O)c2cscn2)cccc1C(=O)Nc1ccccc1 +COC(=O)c1ccc(OCc2cccc(F)c2)c(N)c1 +Cc1nn(-c2cccc(Cl)c2)nc1C(=O)Nc1cccc(C#N)c1 +CC(C(=O)Nc1c(N)cc(Cl)cc1Cl)n1cccn1 +NC(=O)c1ccccc1NC(=O)c1cccc(OCc2ccccc2)c1 +CCOc1cccc2c(C)nc(Nc3ncc4c(n3)CCCC4=O)nc12 +Cc1ccc(C=CCC(=O)Nc2ccc(CS(N)(=O)=O)cc2)cc1 +Cc1oc(-c2cccs2)nc1CC(=O)NC(C)(C)C#N +Cc1ccc(OC(=O)CCC(=O)c2ccc3c(c2)OCCO3)c(C)c1 +CC1(NCc2cccc(C#N)c2)Cc2ccccc2C1 +O=C(CCC1CCCC1)Nc1ccc(CC(=O)NC2CC2)cc1 +O=C(Nc1ccccc1Cn1cccn1)c1ccccn1 +Cc1ccc(NC(=O)CN(C)C(=O)c2ccc(NC3CC3)nc2)nc1 +CCCNC(=O)CN(C)C(=O)C(N)c1ccccc1 +COC(=O)c1ccc(C(=O)NC2(C)Cc3ccccc3C2)o1 +CNS(=O)(=O)c1ccc(NC(=O)c2cccc(COC)c2)cc1 +Cc1nn(Cc2ccccc2)c(C)c1C(=O)NCC(=O)NC(C)(C)C +CCC(CC(=O)N(C)c1nccs1)c1ccc(C)cc1 +O=C(NCCNc1ncccn1)NCc1ccccc1 +O=C(Nc1nc[nH]n1)C1CCCN(C(=O)CCOc2ccccc2)C1 +Nc1ccc(NCCCNC(=O)c2ccco2)nc1 +O=c1[nH]nc(SC2CCCc3ccccc32)n1CC1CCCO1 +O=C(CCNC(=O)c1cc2ccccc2o1)NCc1ccccn1 +CC1CCCC(NS(=O)(=O)Cc2noc3ccccc23)C1C +Cc1nc2c(s1)C(N(C)C(=O)NCCCOCC1CC1)CCC2 +CCC(=O)Oc1ccc2c(=O)c(Cl)coc2c1 +O=C(NC(CO)c1ccccc1)N(Cc1ccco1)c1ccccn1 +Cc1ccc(NCc2ccc3c(c2)OCCO3)cn1 +COc1ccc2[nH]cc(C3=CCN(C(=O)c4ccc[nH]c4=O)CC3)c2c1 +CC1=NC(=O)C(CCC(=O)NC(C)c2ccc(F)cc2F)C(C)=N1 +CC(C)c1ccc(-c2nnc(NC(=O)c3cc[nH]c(=O)c3)s2)cc1 +CCCc1c(CO)nnn1-c1ccc(Cl)cc1C +CC(=O)Nc1ccc(NS(=O)(=O)N2CCOCC2)cc1 +Cc1ccnc(Nc2ncnc(Oc3cccnc3)c2N)c1 +COc1ccc(C(O)CNC(=O)CC(C)C)cc1C(C)C +COC(=O)CC1CCCCN1C(=O)c1ccccc1F +CCOC(=O)C(Cc1nnc(C)n1-c1ccccc1)NC +COCc1nc(C)cc(N2CC(=O)N(C(C)C)C(C)(C)C2)n1 +Cc1nc(N(C)c2ccccc2F)sc1CO +COc1cc(C(=O)N(Cc2cccs2)C2CC2)cc(OC)c1C +Cn1cnc(CNC(=O)Nc2ccc(OC(C)(C)C)cc2)n1 +CN(CCCNC(=O)c1ccc2c(c1)CCO2)S(C)(=O)=O +Cc1cc(C)nc(N2CC(CO)C(CN3CC(C)OC(C)C3)C2)n1 +O=C(NCC1CCOC1)N1CCCC1c1ccccc1 +COc1c(F)cc(NC(=O)N2CCN(C(=O)N(C)C)CC2)cc1F +Cc1cc(-c2nnc(NC(=O)c3ccc4c(c3)CCCC4)o2)n(C)n1 +CN(Cc1ccco1)C1CN(Cc2nccs2)CC2CCCOC21 +O=C(NCC1CC1c1ccccc1)c1cccc(OCC(F)F)n1 +CCc1cc(C(=O)N2CCN(Cc3csc(CC)n3)CC2)[nH]n1 +Cc1cnc(C(=O)N2CCC3(CC2)CNc2ccccc23)cn1 +COC(=O)NCCOC(=O)c1cnn(-c2ccccc2)c1C +C=CCN(Cc1cccs1)C(=O)c1ccc2c(c1)OCCO2 +O=S(=O)(NCC1(c2ccc(F)cc2)CCOCC1)c1ccccc1 +COCCCNC(=O)c1ccnc(C(C)(C)C)c1 +O=C(OCc1cc(-c2ccc(F)cc2F)on1)c1ccc(=O)oc1 +O=C(CCC(=O)c1ccc2c(c1)CCC2)NCc1ccccn1 +COc1cccc(C(=O)N2CC=CC2C(=O)NC2CC2)c1 +CC(C)CNC(=O)Nc1cc(F)ccc1OC(C)C +C#Cc1cccc(N(CC(=O)NC)S(=O)(=O)c2ccccc2)c1 +O=C(Nc1ccc(OCc2cccnc2)cc1)NC1CCC(O)CC1 +COC(=O)C(C)Sc1ncnc2c1cnn2C +CCNC(=O)N1CCCC(c2nc3ccccc3o2)C1 +Cc1noc(C)c1CN(C)C(=O)NC1CCc2c(Cl)cccc21 +Cc1nc(C)n(Cc2cccc(NC(=O)NC(C)C3CCC3)c2)n1 +O=C(CSc1ncc(-c2ccc(F)cc2)o1)N1CCCCC1 +CCNC(=O)CNC(=O)C1CCN(c2ncccn2)CC1 +CC(NC(=O)N1CCN(c2cc(F)ccc2F)CC1)c1ccccn1 +COc1cc(SC)ccc1C(=O)NCCc1nnc2ccccn12 +O=C(CSc1ccc(F)cc1)Nc1nnc(-c2cccc(F)c2)o1 +Cc1nc(C)c(C(C)N(C)C(=O)Nc2ccc3c(c2)COC3)s1 +CCCNC(=O)CCCC(=O)c1ccc2c(c1)OCCCO2 +Cc1cccc(Nc2nc(C(=O)NCc3cccs3)cs2)n1 +CN(CCc1ccc(F)cc1)C(=O)c1ccccc1F +Cc1cc(CN2CCN(C(=O)c3cc4c(s3)CCC4)CC2)no1 +COc1cc(S(=O)(=O)N2CCCCC2C)c(OC)cc1Cl +O=C(C1CC1)N1CC2OCC(=O)N(CC3CC3)C2C1 +CC(=O)NCC1NCCc2c1ccc1ccccc21 +O=C(NCc1ccc(-n2cnc3ccccc32)nc1)c1cccnc1 +CCCCn1c(SCCC#N)nc2ccccc2c1=O +Cn1nccc1CNC(=O)c1sccc1C1CC1 +CCOC(=O)c1nnc2c(-c3cccc(Cl)c3)c(C)nn2c1N +CC(=O)NC1CCCN(C(=O)c2cnns2)C1 +Nc1c(Cl)c(=O)[nH]c(=O)n1Cc1ccccc1 +O=C(CCC1CCCC1)N1CCC(O)(c2cccnc2)CC1 +Cn1cc(C(=O)CC2CCCN2C(=O)c2ccc(Cl)cc2F)cn1 +NS(=O)(=O)c1ccc(C(=O)Nc2ccc(F)cc2)o1 +Cc1cc(C)cc(C2CCN(C(=O)Cc3ccn[nH]3)C2)c1 +CCC1CCCN(C(=O)Cc2c(C)nn(C)c2C)C1 +CCCC1CN(C(=O)Cc2c[nH]c3cc(F)ccc23)CCO1 +Cc1cc(C)n(C(C)CC(=O)Nc2ccc(C)c(Cl)c2)n1 +O=C(CCc1nc(-c2ccsc2)no1)NCc1cccc(Cl)c1 +CCc1ccc(S(=O)(=O)N(C)CCC#N)s1 +CCS(=O)(=O)Nc1cc(C)n(Cc2ccc(Cl)cc2)n1 +NC(=O)Nc1ccc(C(=O)Nc2cccc(CO)c2)cc1 +COC(=O)C(Nc1nccc2c(N)cc(F)cc12)C(C)C +NC(=O)CSc1nnnn1-c1cccc(O)c1 +CC(=O)N1CC(C(=O)N2CCN(S(C)(=O)=O)CC2)C1 +Cc1occc1C(=O)NC1CCN(C(=O)c2ccncc2F)CC1 +Nn1c(COc2cccc(Cl)c2)nc2ccccc2c1=O +CC(NC(=O)c1ccncc1)c1ccc(F)c(F)c1 +FC(F)(F)c1cc(-c2ccco2)nc(-n2cc(Cl)cn2)n1 +Cc1ccc(-c2nnn(CC(=O)N3CCCC3)n2)o1 +Cn1c(N)c(N2CCCCC2)c(=O)n(CC(=O)NC2CC2)c1=O +C#CCOc1ccc(NC(=O)N(C)CC(C)c2nccs2)cc1 +O=C(c1cnc(-c2ccco2)s1)N1CCN(C2CCCC2O)CC1 +CC(C)(C)C(O)CCNC(=O)CC1CCCCC1 +Cc1nn(C)cc1CN1CCOC(c2ccccc2F)C1 +Cc1cc(C)nc(N2CCCC(c3cc(=O)[nH]c(C)n3)C2)n1 +N#Cc1ccc(C(=O)Nc2nc3c(s2)CCC3)cc1 +CNC(=O)NCC(=O)N(C)Cc1ccc(-c2ccccc2)cc1 +O=C1CCCN1c1ccc(CNC(=O)N2CCC2c2ccccc2)cc1 +CN1CC(c2nc(-c3ccc(COc4ccccc4)cc3)no2)CC1=O +CCc1nn2c(=O)cc(COC(=O)c3cc(C)oc3C)nc2s1 +Cc1cnc(-c2nc3cccc(Br)c3o2)o1 +CS(=O)(=O)N(CC(=O)NC1CC1)c1ccc(Cl)cc1F +Cc1cccc(C)c1-n1nnnc1SC1CCOC1=O +CCc1ccc(NC(=O)NC2CC(=O)N(c3cccc(F)c3)C2)cc1 +CC(Sc1ncnc(N)n1)C(=O)Nc1ccccc1 +Cc1cnc(CNS(=O)(=O)CCC2CCCO2)o1 +Cc1cccc(NC(=O)CNC(=O)c2cc(C)n(C)n2)c1 +Cc1cc(C(=O)Nc2ccccc2C#N)nc2c1c(=O)n(C)c(=O)n2C +Cc1nn(C)c2ncc(NC(=O)N(Cc3ccncc3)C3CC3)cc12 +CC=Cc1ccc(OC(=O)C2CCOCC2)c(OC)c1 +O=C(Nn1cnc2ccccc21)N1CCc2ccc(O)cc2C1 +O=C(COc1cccc(F)c1)Nc1ccc(O)cc1 +COc1ccc(CCC(=O)Nc2cccc(N)c2)cc1 +Cc1ccc(-c2ncco2)cc1NC(=O)NC(C)C +COc1cc(CNCC(O)c2ccccc2F)cc2c1OCO2 +CC(C)(C)c1noc(OCCS(=O)(=O)c2ccccc2)n1 +COCC1CCCC12CN(C(=O)c1cccs1)CCO2 +C#CCN1CCN(C(=O)NCc2cccc(NC(C)C)c2)CC1 +CCc1nc2sc(C(C)C)nn2c1S(=O)(=O)NC1CCCC1 +Fc1ccc(NCc2nnc(SCc3ccccc3F)o2)cc1 +COc1ccc(C(=O)NCCc2nc3c(s2)CCCC3)cc1OC +CCOc1ccc(C(=O)CCC(=O)N2CCC2)cc1 +Cc1ccc(-c2ccc(C(=O)NCCC(=O)N(C)C)c(F)c2)cc1 +CCCCN(C)C(=O)c1cc(N)n(-c2cccc(C)c2)n1 +CN(C)C(=O)c1ccc(C(=O)N2c3ccccc3CC2C(N)=O)cc1 +COc1ccc(NCc2ccc(SC)cc2)cn1 +N#Cc1cccc(CNc2cnn(-c3ccccc3)c2)c1 +Cc1ccc2ncc(C(=O)NC3CC(=O)N(C(C)(C)C)C3)n2c1 +CCC(=O)Nc1ccccc1S(=O)(=O)N1CCOCC1 +CCOc1c(CC)cnc2c1c(=O)n(Cc1ccccn1)c(=O)n2C +CN(C(=O)COc1cccc(C#N)c1)c1ccccc1 +CC(COc1ccccc1)OC(=O)Cc1cc2ccccc2[nH]c1=O +CC(C)CNC(=O)c1ccc(-c2ccco2)[nH]c1=O +O=C(NCCCNC(=O)c1cccs1)c1ccc(F)cc1 +Cn1nccc1CNS(=O)(=O)c1ccc(Br)cc1F +C(=Cc1nc2cc3c(cc2[nH]1)OCCO3)c1ccccc1 +CC(C)(C)OC(=O)NCCNC(=O)c1ccco1 +O=C(Nc1ccc2c(c1)OCO2)c1cc(-c2ccccc2)on1 +COC(=O)NCC(=O)NCc1ccc(Cl)cc1Cl +Cc1nnc(SC(C)C(=O)Nc2ccc(C(N)=O)cc2)s1 +O=C(c1ccc2c(c1)CCCC2)N1CCOCC1C1CC1 +Cc1cccc(OCCC(=O)Nc2nccs2)c1 +CC1COCC(C)N1C(=O)c1ccc2c(c1)[nH]c(=O)n2C1CCCC1 +COC(=O)c1ccc2c(c1)nc(C1CC1)n2C(C)(C)C +COc1cc(OC)cc(C(=O)NCCCC(C)C)c1 +CCCc1noc(C2CCCCN2S(=O)(=O)Cc2ccccc2)n1 +CC(=O)c1cnoc1-c1ccc(OC(C)C)c(C)c1 +COc1cccc(-c2nnn(Cc3ccc(F)c(F)c3)n2)c1 +O=C(COc1ncnc2c1cnn2-c1ccccc1)N1CCCCC1 +CC(C)c1nc(C(=O)N2CCc3ccccc32)n(-c2ccccc2)n1 +Cc1cc(Cl)ccc1-n1ncc2c(N3CCOCC3)ncnc21 +O=C(CCS(=O)(=O)c1ccccc1)N1CCC1c1ccc(F)cc1 +COc1cccc2c1N(C(=O)CCn1cc(C)cn1)CCC2 +Cc1ccc(NC(=O)c2cc(F)cc(F)c2)c(O)c1 +COc1cc(Cl)c(C)cc1-n1ccnc1SCCO +COC(=O)c1sccc1Cn1ncnc1-c1cccc(C#N)c1 +CN(C(=O)c1[nH]ncc1Br)C1(C#N)CCC1 +O=C(OCc1ccccn1)c1cc2cc(Cl)ccc2o1 +Cc1nc(C)c(CC(=O)NC2CCN(c3ccccc3)CC2)c(=O)[nH]1 +CC1CN(CCC(O)c2cc(Cl)ccc2Cl)CC(C)O1 +COc1cc(OC)cc(-c2nnc(SCC(=O)C(C)(C)C)o2)c1 +O=C(CCn1nc2ccccn2c1=O)N1CCc2cc(F)ccc2C1 +CS(=O)(=O)c1ccc(-c2nnn(Cc3ccccc3F)n2)cc1 +CCn1nc(C)cc1C(=O)NCC(=O)Nc1ccc2c(c1)OCCO2 +O=C(Nc1cccc(N2CCCC2=O)c1)c1cc(-c2ccccc2)on1 +Cc1n[nH]c(C2CCCN2S(=O)(=O)c2cccc3cccnc23)n1 +O=C(NC1CC1)C1CC12CCN(c1cc(C(F)(F)F)ncn1)C2 +C=CCn1c(SCC(=O)Nc2ccc(C)c(F)c2)nnc1C1CC1 +Cc1cnc(C(=O)OCC(=O)N(C)C2(C#N)CCCCC2)cn1 +CC(C)(C)OC(=O)N1CCc2ccsc2CC1 +CC(=O)c1cccc(-c2cnn(CCN3CCOCC3)c2)c1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NC1CCCC1 +O=C(Nc1ccc(-n2cnnn2)cc1)c1cnn(Cc2ccccc2)c1 +Cc1cccc(C)c1-n1nnnc1CN1CCOC(C)(C)C1 +CCN(CC)C(=O)CNc1cc(N2CCCS2(=O)=O)ccc1F +COCCN(CC(F)(F)F)C(=O)Cc1cn(C)c2ccccc12 +Cc1nn(CCc2ccc3c(c2)CCO3)c(C)c1N +CCC(CC)NC(=O)COC(=O)c1ccc(C#N)cc1 +COC(=O)c1nn(C)c(N)c1-c1ccc(C(C)C)cc1 +CCCC(=O)NCC(=O)N(C)Cc1csc(C)n1 +COc1cccc(C(=O)Nc2ccccc2-c2nncn2C)c1 +Cc1n[nH]cc1NC(=O)c1ccc(F)cc1Cl +CC(C)(C)C(=O)N1CCn2nc(-c3ccccn3)nc2C1 +CC(C)CC1COCCN1C(=O)C1CCCN(C(=O)C(C)(C)C)C1 +COC(=O)CCCNC(=O)c1ccc(F)cc1N +O=C(NC1CC1)C(c1ccccc1)N1CCc2cncnc2C1 +CCC1C(=O)NCCN1Cc1cccc(Cl)c1F +CC1CCN(C(=O)CCc2cnn(C)c2)c2ccccc2S1 +CCOc1ccc(C(=O)n2cnnc2N)cc1OCC +CCn1cc(C(=O)Nc2ccc(OC)c(OCC(F)(F)F)c2)cn1 +CC1(CS(=O)(=O)NCc2cccc3c2OCO3)CCCCC1 +C#Cc1cccc(N(CC(=O)NC)C(=O)c2cccc(NC(C)=O)c2)c1 +NC(=O)c1cccc(OCc2ccc(Cl)c3cccnc23)c1 +COc1cc2c(cc1Cn1ccnc1C1CC=CCC1)OCCO2 +CC(NC(=O)Nc1nccs1)c1ccc2c(c1)CC(=O)N2 +Cc1cc(C(=O)NC2CCCCNC2=O)c2c(=O)[nH]n(C)c2n1 +O=C(COC(=O)c1cc(=O)c2ccccc2o1)Nc1cccc(F)c1 +O=C(Nc1cccc(C#Cc2ccccn2)c1)c1ccco1 +CC(C)C(=O)N1CCCC1C(=O)Oc1ccc(Cl)c(Cl)c1 +COc1cc(C(O)COc2ccc(C)cc2N)c(OC)cc1SC +Cc1n[nH]c(C2CC3CCN(C(=O)Cc4ccccn4)CC3O2)n1 +O=C(NCc1ccc2c(c1)OCO2)c1sccc1-n1cccc1 +Cn1nc(C(F)(F)F)c(C#N)c1N1CCN(c2ccccc2)CC1 +Cc1sc(-c2ccn[nH]2)cc1NC(=O)c1cc(F)ccc1F +O=C(NCC(O)c1ccc(F)c(F)c1)c1ccc[nH]c1=O +O=C(NCc1cccs1)c1cnn(-c2ccccc2)c1-n1cccc1 +CCc1cccc(C)c1NC(=O)c1ccc(F)c(NC(C)=O)c1 +COc1ccc(C(=O)CCN2CCC(=O)CC2)cc1 +Cc1cnc(C(=O)Nc2ccc(OC(F)F)c(F)c2)cn1 +CC(C)(C)OC(=O)N1CCNC(c2ccc(O)cc2)C1 +CC(NC(C)c1ccc(F)c(F)c1)C(=O)NC1CC1 +CCn1nc(C(=O)Nc2cccc(C)c2)ccc1=O +N#Cc1ccsc1NC(=O)COC(=O)c1ccc(O)cc1 +COCc1ccc(C(=O)NCCc2ccccc2OC)cc1 +CCn1cnnc1CNC(=O)NCCOc1cccc2ccccc12 +COCCN1C(=O)CC2C1CCN2C(=O)c1cnc2ccccc2c1 +Cc1cc(C)n(-c2ccc(C(=O)N(C)C(C)C3CC3)cc2)n1 +COc1cc(CC(=O)NCc2ccccn2)cc(OC)c1OC +CCCc1nc(NC(C)c2c(C)n[nH]c2C)c2cnn(C)c2n1 +Cc1cc(C)c2nc(NC(=O)c3ccoc3C)sc2c1 +Clc1cccc(Cl)c1CNc1cnns1 +Cc1cnc(C(=O)NCC2Cc3ccccc3O2)cn1 +COc1ncccc1CNC(=O)NC(C)c1ccccc1C +N#CC(NC(=O)c1ccc2c(c1)OCO2)C1CCCCC1 +C#CCCOC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +CN(CCn1cccn1)c1ccc(C(=O)N2CCc3ccccc32)cn1 +Clc1ccc(Cc2nnc(-c3ccco3)o2)cc1 +Cc1cc(C)c(OCC(=O)NCCc2ccco2)c(C)c1 +CCN(CCO)S(=O)(=O)c1ccc(OC(C)C)c(C)c1 +O=C(COc1cccc2c1CCCC2)N1CCOCC1 +COc1cccc(C(=O)N(CCc2cccc(F)c2)C2CC2)c1 +Cc1ccc2c(c1)OCC(=O)N2CC(=O)c1ccc(Cl)cc1 +C=CCn1c(SCC(=O)NC2CC2)nnc1-c1cccc(Cl)c1 +CC(c1ccc(Cl)cc1)N(C)C(=O)C1CCCO1 +Cc1nc(C)n(Cc2cccc(NC(=O)NC(C)(CO)C3CC3)c2)n1 +CNC(=O)c1cccc(CNC(c2ccccc2)c2ccccn2)c1 +CC(C)CC(=O)Nc1ccc(NC(=O)N(C)C(C)CC#N)cc1 +C=CCn1c(C)nnc1S(=O)(=O)Cc1ccc(F)cc1Cl +Cc1ccc(C(=O)NCc2ccc(CN3CCCC3=O)cc2)c(O)c1 +CN(C)c1nc(N)nc(CN2CCC(Oc3ccccc3Cl)C2)n1 +Cn1cc(CCCCNC(=O)C2CSc3ccccc32)cn1 +O=C(NCc1cc(Cl)c2c(c1)OCCCO2)c1cc(C2CC2)[nH]n1 +CC1(C)CN(C(=O)CC(C)(C)c2ccccc2)CCO1 +Cc1cncc(C2CCN(S(=O)(=O)c3ccccc3)CC2)n1 +CN(C)C(=O)CCNc1cc(-c2ccccc2)nc2ccnn12 +O=C(NCc1ccc(S(=O)(=O)NC2CC2)cc1)Nc1cccnc1 +CCn1nc(C)c(CCN(C)C(=O)NCc2ccc(F)cc2)c1C +CC(=O)c1ccccc1N1CCc2ccccc2C1 +N#Cc1c(CCCNc2nnnn2-c2ccccc2)n[nH]c1N +c1cncc(-c2nnc3sc(-c4ccc5c(c4)OCO5)nn23)c1 +O=C1CC(NS(=O)(=O)c2c(F)cccc2F)CN1C1CC1 +O=C1Nc2c(c(=O)oc3ccccc23)C(c2cccnc2)N1 +Cc1cc(C)n(-c2ccc(C(=O)NC3C4CCOC4C3(C)C)cn2)n1 +COc1ccc(Cl)cc1NC(=O)COC(=O)c1ccccc1N +Cc1nc(C)c(COC(=O)C2COc3ccccc32)s1 +Cc1ccc(-c2ocnc2C(=O)OCC(N)=O)cc1 +CCc1cc(=O)[nH]c(SCC(=O)Nc2nc(C)cs2)n1 +CCCCN(C)C(=O)Nc1ccc(F)c(C(=O)NC)c1 +CC(C)C(C(=O)Nc1cc[nH]n1)N1CCCC1=O +O=C(NCC(=O)N1CCOCC1)c1ccc(-c2ccccc2)cc1 +CCCCN(C)C(=O)Nc1ccc(OCC(N)=O)cc1 +CC(NC(=O)COCC(F)(F)F)c1ccc(-n2ccnc2)cc1 +Cc1ccc(C(C)NC(=O)NCCCN2CC(C)OC(C)C2)cc1 +COCCN1CCN(Cc2nc(Cc3ccccc3)no2)CC1=O +Cc1ccc(-c2cnc(-c3ccccc3C(=O)NCCO)o2)cc1 +N#Cc1ccc(S(=O)(=O)NC2CCc3cc(Cl)ccc32)cc1 +CCC(=O)Nc1nc2nc(C)c(Cl)c(C)n2n1 +Cc1ccccc1C(C)NC(=O)COc1ccc(C#N)cc1 +CCN(Cc1cccc(C)c1)C(=O)c1cc(NC(C)=O)ccc1F +CCCCS(=O)(=O)N1CCCC(C(=O)Nc2ccc(O)cc2)C1 +C=CCN1C(=O)COc2cc(NCc3ccccc3F)ccc21 +CCOc1cc(C(=O)NCCOC)cc(Cl)c1O +Cc1cccc(CCN(C)C(=O)C(N)c2ccccc2)c1 +O=C(c1scnc1C1CC1)N1CCCC1c1ccncc1 +Cc1nc(-c2ccc(C(=O)NCc3ccccn3)cc2)no1 +COC(=O)N1CCC(CNC(=O)Nc2cccc(OC)c2)CC1 +Cc1cccc(C)c1NC(=O)NC(C)C(=O)NCc1ccccc1 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+COc1cc(OC)cc(C2NC(=O)N(C)C3=C2C(=O)N(C(C)C)C3)c1 +CCOC(=O)CC(O)(c1ccc(Cl)cc1)C(C)C +Nc1ccccc1OCCNC(=O)c1ccc(F)c(F)c1 +CNC(=O)N1CC2CC(C(=O)NCc3ccccc3)C(C1)O2 +CC(C)CN(C(=O)CN1CCOC(c2ccccc2)C1)C1CC1 +O=S(=O)(CCN1CCOC(Cn2cccn2)C1)c1ccccc1 +CC1CC1CNC(=O)c1[nH]nc(C2CC2)c1Br +CCC1CCCCN1C(=O)c1cn2ccccc2n1 +CSc1ccc(OC(C)C(=O)NCc2csc(C3CC3)n2)cc1 +CC1CCc2c(cnc3nc(-c4ccncc4)nn23)C1 +COC(C)C(=O)N(C)C(C)c1ccc(Cl)cc1Cl +Cc1nn(C)c(C)c1CNCC1(c2ccc(F)cc2)CC1 +CC(=O)N1CCc2ccc(NC(=O)Nc3c(F)cccc3F)cc2C1 +COc1cccc(NC(=O)Nc2ccc3snnc3c2)c1 +COCCN1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1=O +O=C(NC1CCCCC1)c1occ2c1OCCO2 +COCCc1noc(CN(C)Cc2coc3ccccc23)n1 +O=C(NCC1CCCO1)c1ccc(NC(=O)c2ccco2)cc1 +Cc1ccc2c(c1)CCCN2C(=O)CCn1ccccc1=O +COC(=O)c1ccc(OCC(=O)C(C)(C)C)c(OC)c1 +COc1ccc(OC)c(C(=O)CCNc2cccc(F)c2)c1 +CN(Cc1ccccc1)C(=O)NCCC(=O)Nc1cccc(F)c1 +COCc1ccccc1C(=O)OCC(=O)N1CCCCCC1 +Cc1cc(CN2CCN(c3ccc4nncn4n3)C(C)C2)no1 +Cc1cc(Cl)ccc1OCCc1ncc(CO)s1 +CC(=O)N(C)Cc1cccc(NC(=O)c2cnc3ccc(C)cn23)c1 +Cc1nn(-c2ccccc2)c(C)c1C(=O)N(C)Cc1cccc(C#N)c1 +O=C(NCc1ccco1)c1ccnc2c(Br)cccc12 +COc1cc(N2CCOC(c3ccc(Cl)cc3)C2)ncn1 +CC1CCC(C(=O)N2CCN(C(=O)OC(C)(C)C)CC2(C)C)O1 +CN(Cc1ccccc1F)C(=O)CSc1ccccc1O +CCC(=O)Nc1ccc(C(=O)CSc2nnc3ccccn23)cc1 +CC(C)CNC(=O)C(C)NC(C)c1ccc(F)cc1F +N#Cc1c(-c2ccccc2F)nn(-c2cccc(F)c2)c1N +CNC(=O)Nc1cccc(NC(=O)CNC(=O)CC2CCCCC2)c1 +Nc1cc(S(=O)(=O)Nc2ccc(F)cc2)ccc1Cl +COCCN(C)C(=O)Nc1ccc(OC)c(Cl)c1 +Cc1ccc(OCCNC(=O)CN2CCCCCC2=O)cc1 +N#CCCCS(=O)(=O)c1nccn1-c1cccc(Cl)c1 +COc1ccc(NC(C)=O)cc1NC(C)C(=O)N(C)C +Cc1noc(NC(=O)Nc2ccccc2F)c1C#N +CC(C)CC(=O)N1CCCC(NS(C)(=O)=O)C1 +O=C(Nc1cccnc1)c1cnc2snnc2c1 +CN(C(=O)NC1CCOCC1)C(c1ccccc1)c1ccccn1 +CC(C)c1nnc(SCC(N)=O)n1CC1CCCO1 +Cn1cc(NC(=O)c2ccc(Cl)c(C#N)c2)ccc1=O +CC(C(=O)NC1CCCC1)S(=O)(=O)c1cccc(Cl)c1 +COc1ccc(OC)c(C(O)CNC(=O)NCc2cccs2)c1 +O=C1Cc2cc(NS(=O)(=O)Cc3ccc(F)cc3)ccc2N1 +CCN(CC(=O)NC)C(=O)Cc1cn(CC)c2ccccc12 +COc1cccc(N2CC(C(=O)NCCc3ccsc3)CC2=O)c1 +CN(C)C(=O)CN(C)C(=O)c1cncn1-c1ccccc1 +CSc1ccc(NC(=O)Nc2cccc(C)n2)cc1 +CCc1n[nH]c(NC(=O)c2ccc(N(C)C)cc2F)n1 +COC(=O)CCC(N)C(=O)c1cc(Cl)ccc1C +NS(=O)(=O)c1ccc2c(c1)CCN2Cc1ccccc1Cl +O=C(CCc1ccncc1)N1CCN(C(=O)c2cccs2)CC1 +N#CCCn1c(C2CCC2)nc2cc3c(cc21)OCO3 +CC(C)NC(=O)c1ccc(NCc2noc(C(C)C)n2)cc1 +Cc1ccncc1NC(=O)NC1CCN(c2cccs2)CC1 +COc1ccc(CN2CCN(C(=O)Cn3cccnc3=O)CC2)cc1 +COc1cccc(CCC(=O)Nc2nc3ccccc3[nH]2)c1OC +CCCCS(=O)(=O)N1CCN(CC(C)C#N)CC1 +COc1ccc(-n2nc(C)nc2-c2cncc(C)c2)cc1 +CC1CCCC(C)N1C(=O)c1onc(S(C)(=O)=O)c1N +COCc1nc2c(NC(=O)COc3ccc(C)cc3)cccn2n1 +COc1ccccc1CCNC(=O)CCc1nc2ncccc2[nH]1 +CCOC(=O)C1(NC(=O)c2c(F)ccc(OCC)c2F)CCCC1 +Cc1ccc(C(=O)CCC(=O)NC(C)c2c(C)noc2C)s1 +COc1ccc(C(=O)NCCc2ccc(OC(F)F)cc2)cn1 +Cc1ccccc1NC(=O)CCNC(=O)c1ccco1 +Cc1cc(C(=O)CN2CCn3c(nn(C)c3=O)C2)c(C)n1C1CC1 +C=CCN1CCN(S(=O)(=O)c2ccc(C(N)=O)o2)CC1 +Cc1cccc(C(=O)NCc2ccc(C(=O)N(C)C(C)C)cc2)n1 +Cc1ccn(C(C)CC(=O)Nc2cc(Cl)ccc2C)n1 +CCC(OC)C(=O)Nc1ccc(C(=O)NC)c(Cl)c1 +CCn1cnnc1CNC(=O)CCN1C(=O)COc2ccccc21 +C=CCN(CC=C)C(=O)C1(C)Oc2ccc(C)cc2NC1=O +CCOCc1c(C(=O)N(C)CC(N)=O)oc2ccccc12 +CCC(CNC(=O)Nc1ccnc(C(=O)N(C)C)c1)c1ccccc1 +CC(C)(CO)NC(=O)CC1C(=O)NCCN1Cc1cccc(F)c1 +CN(Cc1ccc(O)cc1)C(=O)C1CC1c1ccccc1 +COc1ccc(C(C)=O)c(OC(=O)C(C)Oc2ccccc2)c1 +CS(=O)(=O)NC1CCCN(C(=O)c2ccccn2)C1 +CCOc1ccccc1N(C)C(=O)Cc1cccc(OCC#N)c1 +CC1CCCN(C(=O)COC(=O)c2ccc(N)cc2)C1 +Cc1cc(C(=O)NCc2cccnc2-n2ccnc2)c(C)o1 +C#Cc1cccc(NC(=O)c2cc(S(N)(=O)=O)oc2C)c1 +COc1ccc(NC(=O)N(Cc2cccn2C)C2CC2)cc1OC +CCNC(=O)CN(CC)C(=O)C1CCCCN1C(=O)c1ccccc1 +CC(NC(=O)c1ccc(-c2ccccc2)[nH]c1=O)c1nncn1C +O=S(=O)(NC1(CO)CCCCC1)c1cc[nH]c1 +O=C(CC1(O)C(=O)Nc2ccccc21)c1ccc(Br)cc1 +NC(=O)c1cccc(C(=O)N(CC2CCC2)CC(F)(F)F)c1 +O=C(CCc1nc2ccccc2[nH]1)Nc1ccc2occc(=O)c2c1 +N#Cc1cccc(Cl)c1N1CCC(CS(N)(=O)=O)CC1 +NC(c1ccc(Br)cc1)c1nccn1Cc1ccccc1 +Cc1ccc(C(O)CNC(=O)c2ccccc2F)cc1 +CNC(=O)CC1CC(C)(C)Oc2ccc(Cl)cc21 +Cc1n[nH]c(C)c1CNC(=O)C(C)N1C(=O)c2cccc3cccc1c23 +COc1ccc(C)cc1C(O)CCCC(=O)N1CCOCC1 +CC(Sc1nc(-c2cccs2)n[nH]1)C(=O)N(C)CCC#N +NC(=O)CSc1nccc(-c2ccc(OC(F)F)cc2)n1 +Cc1cc(C(=O)NC2CCCc3nc(-c4cccnc4)ncc32)nn1C +Cc1ccc(OC2CCN(C(=O)CN(C)S(C)(=O)=O)CC2)nn1 +Cc1ccc(CCC(=O)N2CC(O)CC2C2CCCCC2)o1 +O=C(Nc1cnn(C2CCOC2)c1)Nc1ccccc1Cl +CCOc1ncnc(NCc2ccccc2OC)c1N +CC(O)c1cn(C2CCN(c3ncnc4[nH]cnc34)CC2)nn1 +CC(NC(=O)c1n[nH]c(=O)c2ccccc12)C1CCCO1 +O=C(NC1CCN(c2nccs2)CC1)c1cccs1 +CC(=O)c1cccc(NC(=O)Nc2cnccn2)c1 +CC(NC(=O)c1cccs1)C(=O)N1CCCCC1 +Cc1cccc2sc(NC(=O)c3n[nH]c(=O)c4ccccc34)nc12 +C#CCOc1ccc(CCNS(=O)(=O)N2CCOCC2)cc1 +CC(C)OC(=O)c1cccc(-n2nnc(CO)c2C(C)C)c1 +CCC(CCNS(=O)(=O)c1cnn(C)c1C)n1cc(Cl)cn1 +COc1cc2c(cc1OC)CN(C(CN)c1ccco1)CC2 +CC(C)NC(=O)NCc1ccccc1-n1ccnc1 +COc1ccc(CCC(=O)Nc2nnc(CC(C)C)s2)cc1 +CCOc1ccccc1OCC(=O)Oc1ccc(F)cc1 +COc1ccc(NC(=O)N2CCOCC2)cc1Cc1ccccc1 +COc1ccc2nc(SC3CCOC3=O)[nH]c2c1 +CC(NC(N)=O)C(=O)N(C)Cc1ccc2c(c1)OCO2 +CC(NC(=O)NCCN(C)c1ccccc1)C(=O)N1CCCCC1 +N#CCOC(=O)C1CCN(S(=O)(=O)c2cccs2)CC1 +Cc1onc(COc2ccccc2O)c1Br +O=C(NCCc1cc(F)cc(F)c1)C1CCN(c2cnccn2)CC1 +COc1ccc(S(=O)(=O)Oc2c(C)nn(C)c2C)cc1Cl +CC(C)Cc1ncc2c(n1)CN(c1noc(C(C)C)n1)C2 +COc1c(C(=O)N(C)Cc2nc(C(F)(F)F)cs2)c(C)nn1C +COc1cccc(CNC(=O)Cc2ccsc2)c1 +CN(C1=NS(=O)(=O)c2ccccc21)c1ccc(O)cc1 +CCc1nc(COc2ccc(F)cc2)sc1CC#N +CCOC(=O)C(NC)c1nc2cc(N)ccc2n1C +CC(C)(C)OC(=O)COC(=O)c1ccc(Cl)c(N)c1 +O=C(C1CCC1)N1CCCN(S(=O)(=O)c2ccccc2)CC1 +c1nc(CNCC2(c3ccc4c(c3)OCCO4)CCCC2)cs1 +CC(CNC(=O)c1ccc(N2CCOC2=O)cc1)c1cccs1 +COCCOc1ccc(CNC(=O)N2CCCC(O)C2)cc1 +O=S(=O)(CCc1ccccc1)NCC(O)c1ccc2c(c1)CCO2 +Cc1noc(C)c1COC(=O)C(O)(c1ccccc1)c1ccccc1 +CCCOc1cc(CO)cc2c1OCC(=O)N2CCCO +O=C(Nc1cnc(C2CC2)nc1)c1c(Cl)ccc(Cl)c1Cl +O=c1[nH]c2cc(S(=O)(=O)N3CC4C5CCC(CC5)C4C3)ccc2o1 +COc1ccnc(NC(=O)COc2ccc(C)cc2OC)c1 +CCS(=O)(=O)N1CCCN(c2ncccc2C#N)CC1 +COc1ccc(-c2cn(-c3ccc(C)c(Cl)c3)c(=O)[nH]2)cc1OC +Oc1cccc(CNCCc2nc3ccccc3s2)c1 +COCCCN(C)C(=O)CNC(=O)c1ccccc1C +Cc1cccc2cc(CN(CC3CCCO3)C(=O)C(C)C)c(=O)[nH]c12 +COC(=O)c1cc(CNC(=O)Nc2ccc(C)cc2C)oc1C +CC(=O)Nc1nc(CC(=O)NC2CCCC2)cs1 +O=C(Cc1cccc(F)c1)NCCNC(=O)NC1CC1 +CCC1CCC(NC(=O)Cc2ccc(C)nc2)CC1 +CC1CN(C(CNC(=O)C2CC2)c2c(F)cccc2Cl)CCO1 +CCCn1c(-c2cccc(C(=O)NC3CC3)c2)nc2cccnc21 +COc1ccnc(NC(=O)Cc2ccc(F)cc2)c1 +CC(CN1CCCC1=O)NC(=O)c1ccc(Cl)c(Cl)c1 +Cc1ccc(CNC(=O)c2ccc(-c3ccsc3)nc2)cc1 +O=C(NCCc1c[nH]c2ccccc12)c1ccc2[nH]cnc2c1 +COc1cc(CO)cc2c1OC(C)C(=O)N2Cc1ccccc1 +CN(C)c1ccc(C(=O)NCCC(C)(C)C)cc1F +CCc1nc(NC(=O)Cc2cc(C(C)=O)ccc2OC)sc1C +CCN(Cc1ccco1)C(=O)Nc1ccccc1SC +CC(=O)c1cccc(NC(=O)c2ccc(C)c(N)c2)c1 +Cc1cc(NCC(=O)N(C)C2CC2)ccc1C(=O)NC(C)C +Cc1ccccc1C(=O)Nc1ccc(CC(N)=O)cc1 +O=C(Nc1ccc(F)cc1)Nc1nnc(Cc2ccc(F)cc2)o1 +Fc1ccc(CC2CN(Cc3ccccn3)CCO2)cc1 +CC(=O)NCCNC(=O)C1(c2cccc(Cl)c2)CC1 +CNc1ccccc1C(=O)NCCc1ccsc1 +COc1ccc2oc(C(=O)NCc3nc4ccccc4[nH]3)c(C)c2c1 +Cc1noc(C)c1C(=O)NC1CCc2nnc(C)n2C1 +Cn1cnnc1C1CCCN(C(=O)NCc2ccccn2)C1 +c1cncc(CN(Cc2cnc3ccsc3c2)CC2CCCO2)c1 +CCN(Cc1cc2ccccc2[nH]c1=O)C(=O)c1ccc(F)cc1 +COc1ccc(CC2=Nc3cc[nH]c(=O)c3C2=O)cc1 +Cc1nc(COc2ccc(Cl)cc2)sc1C(=O)NCCO +CNC(=O)c1ccc(CNc2cccc(-c3n[nH]c(C)n3)c2)cc1 +Cc1cc(-c2nc3c(c(=O)[nH]2)CCCC3)c(C)s1 +O=C(CCCSc1ccccc1)NCC1COc2ccccc2O1 +Cc1ccc(F)cc1NC(=O)NCC(=O)Nc1ccc(F)cc1 +CNC(=O)C(C)OC(=O)c1nc(-c2ccc(Cl)cc2)oc1C +CCc1ccccc1NC(=O)c1nc(N)ccc1Cl +O=C(NCc1ccc(CO)c(F)c1)Nc1ccc2c(c1)OCO2 +Nc1ncnc2c(C3OC(CO)C(O)C3O)nsc12 +CN1CC2(CCN(C(=O)Cc3ccc(O)c(F)c3)CC2)OC1=O +CCn1nc(C)c(S(=O)(=O)NCc2ccncc2)c1C +CCCCOc1nc2c(c(=O)n(C)c(=O)n2C)n1C +CCC(C)C(=O)Nc1cc(OC)c(OC)cc1Cl +COc1ccc(-n2ncnc2-c2cc(-c3cnn(C)c3C)on2)cc1 +CS(=O)(=O)N1CCCC(CSc2cccc(C#N)c2)C1 +COc1ncccc1NC(=O)NC1CCN(S(C)(=O)=O)CC1 +CC1CC(c2ccccc2F)N(C(=O)NCc2ncn(C)n2)C1 +Cc1oc(-c2ccc(Cl)cc2)cc1C(=O)CC#N +O=C(c1cnccn1)N1CCc2onc(Cn3cccn3)c2C1 +O=C(c1cccnc1)N1CCC2(C1)CN(C(=O)c1cccs1)C2 +c1csc(-c2nnc(CSc3ncn[nH]3)o2)c1 +NC(=O)Nc1ccc(CNC(=O)Cn2ccccc2=O)cc1 +COc1ccc(C(=O)Nc2ccc(Oc3ccccc3)cn2)nn1 +COc1ccc(C(CCO)c2ccccc2)cc1F +CC(C)(C)OC(=O)C1CCCN1C(=O)Nc1ccc(F)cc1F +CC(C)CC(C)N(C)C(=O)Nc1ccccc1CC(N)=O +COCC(C)OC(=O)c1ccn(-c2ccccc2F)n1 +CC(NC(=O)CNC(=O)CNC(=O)c1cccs1)c1ccccn1 +Cc1cc(C)c(NC(=O)NCc2ccnn2C)c(C)c1 +CCc1c(C)sc(NC(=O)C2CC2)c1C(=O)OC +COC(CNC(=O)Nc1cc(C)cc(C)c1)c1ccsc1 +O=C(c1ccc(=O)[nH]c1)N1CCC(c2nnc(-c3ccco3)o2)CC1 +Cc1cccc(NC(=O)c2ccccc2S(C)(=O)=O)c1C +O=c1cc(C2CCC2)ncn1CC(O)c1cccc(F)c1 +Cc1ccc(-n2cnc(C(=O)Nc3ccc(C)c(C)c3)n2)cc1 +CCOCCNC(=O)NCC(C)(C)N1CC(C)OC(C)C1 +Nc1cccc(CCc2nnc3c(n2)CCCC3)c1 +Cc1csc(CNC(=O)CSc2nccn2C)n1 +Cn1nnc2cc(C(=O)N3CCSc4ccc(Cl)cc43)cnc21 +Nc1cccc(S(=O)(=O)N(CCO)C2CC2)c1 +COc1ccc(F)cc1NC(=O)N(C)Cc1ccc2c(c1)OCO2 +CCC(C)C(NC(=O)c1ccc(-c2cccs2)nc1C)C(=O)OC +COc1cc(C2NCCc3ccc4[nH]ccc4c32)ccn1 +O=C(NCc1ccccc1-n1cccn1)c1cc2ccccc2oc1=O +Cn1ccc(NC(=O)Nc2ccc(CCC(=O)N3CCCC3)cc2)n1 +CCN1CC(C(=O)NC2(Cc3ccc(Cl)cc3)CC2)CC1=O +COc1ccc(C(=O)N2CCCC(c3noc(C(C)C)n3)C2)nn1 +COC(=O)CCN(C)C(=O)c1ccc(CO)cc1 +CC(=O)NCCCCCC(=O)N(C)c1cccc2ccccc12 +Cc1cc(CNC(=O)Nc2c(C)ccn(C)c2=O)ccc1Cl +CCCc1nnc2sc(COc3cccc(C)c3)nn12 +CC(C)N(CCCO)S(=O)(=O)c1ccc(F)cc1F +O=C(Nc1cc(F)cc(N2CCCC2)c1)NC1C=CC(CO)C1 +Cc1nc(Cn2cccc2C(=O)Nc2ccccc2C)no1 +Cc1cccc(N)c1S(=O)(=O)NCCc1cccs1 +CCn1ncc2cc(C(=O)Nc3ccc(F)cc3)c(N)nc21 +O=c1c2c3c(sc2ncn1CC1CCCO1)CCCC3 +NC(=O)C1CCCCN1C(=O)Cn1cnc(C2CCC2)cc1=O +O=c1[nH]cccc1NS(=O)(=O)c1ccccc1 +Cn1ccnc1C(NC(=O)C1CC1)c1ccc(F)cc1 +CCc1nc2sc3c(c2c2nnnn12)CCCC3 +COC(=O)CN(C(=O)c1ccc(Cl)c(N)c1)C(C)C +Cc1cc(C)c(S(=O)(=O)NCCOCCO)c(C)c1 +CN(Cc1ccccc1)c1ncnc(NCC2CCCO2)c1N +CN(Cc1ccccc1C(F)(F)F)C(=O)Cc1ccc[nH]1 +O=C(NCc1nncn1C1CC1)Nc1ccccc1Oc1ccccc1 +O=C(Nc1ccn(-c2ccccc2)n1)Nc1ccn(-c2ccccc2)n1 +Cc1noc(CNC(=O)NCc2cccc3ccccc23)n1 +CCCc1nnc2sc(Cn3ncc4ccccc43)nn12 +N#CCc1ncc(-c2ccccc2Br)[nH]1 +O=C(Nc1c(F)cccc1F)c1ccc(OCC2CCCO2)cc1 +Cc1cc(C)c2c(N)c(C(=O)N(C)Cc3ccccc3)sc2n1 +CCS(=O)(=O)N1CCC(C(=O)N2c3ccccc3CC2C)CC1 +Cc1cccc(CN(C(=O)CNC(=O)c2cccc(C)c2)C2CC2)c1 +CN(CCC(F)(F)F)C(=O)CCc1nc(-c2ccsc2)no1 +COc1ccccc1C(=O)N1CCCC1c1cc(C)on1 +COc1ccc(-c2cc(C#N)nc(N(C)C)n2)cc1OC +CC1=NC(n2cc(C(=O)c3cc(C)ccc3O)cn2)=NC(=O)C1 +O=C(c1cccs1)N(Cc1ccco1)c1ccc(O)cc1 +Cc1nnc(C)n1NS(=O)(=O)c1ccc2ccccc2c1 +O=C(Cc1ccc[nH]1)Nc1cccc(-c2nnc3n2CCCCC3)c1 +COC(=O)CCNC(=O)CN(C)c1cccc2ccccc12 +Cc1csc(S(=O)(=O)C(C)C(=O)Nc2cc(F)ccc2C)n1 +O=C1CN(C(=O)Nc2cccc(OC(F)F)c2)CCN1 +CCCCOC(=O)C1C2C=CC3(CN(Cc4ccccc4)C(=O)C13)O2 +Cc1cccc(Cl)c1NC(=O)Cn1c(=O)n(C)c2ccccc21 +CCNC(=O)c1ccc(-c2ccnc3[nH]ccc23)s1 +O=C1Nc2c(Cl)cccc2C12CC(O)=Nc1[nH]ncc12 +CC(C)c1ccc(N2CCN(CC(=O)N3CCOCC3)C2=O)cc1 +Cc1ccccc1C1CN(C(=O)CNCC(F)(F)F)C(C)CO1 +O=c1[nH]c(=O)c2ncn(S(=O)(=O)c3ccc(F)cc3)c2[nH]1 +Cc1cc(NC(=O)CCCc2nc(-c3ccc(Cl)cc3)no2)no1 +CCCOc1ccc(-c2nc(C(C)N)cc(=O)[nH]2)cc1OC +CCCCNC(=O)C1CC(=O)N(c2ccc(SC)cc2)C1 +CC(C)CN1CC(C(=O)N(C)Cc2ccsc2)CC1=O +CCN(Cc1ccccc1Cl)C(=O)Nc1nncs1 +COc1ccc(NS(=O)(=O)CC23CCC(CC2=O)C3(C)C)cc1 +Nc1ccc(NC(=O)c2ccc(F)cc2Br)c(Cl)c1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)N1CCCC1 +COc1ccc(CNC(=O)NCC(OC)c2ccc(C)s2)cc1 +CS(=O)(=O)N1CCC(CNC(=O)c2ccc(F)c(F)c2)CC1 +O=C(c1ccccc1OC(F)F)N1CCOCC1 +CC(=O)Nc1ccc(C)cc1NC(=O)c1ccccc1O +CC(C)CS(=O)(=O)c1nc2ncc(Br)cc2s1 +Cc1cc2c(=O)n(Cc3csc(N(C)C4CC4)n3)cnc2s1 +CC1CCCC(NC(=O)C(C)N2CCN(C(=O)CO)CC2)C1C +Cc1[nH]c(-c2nc(-c3ccsc3)no2)c(C)c1S(N)(=O)=O +CC1CN(CCCc2cnn(C)c2)CCN1C(=O)OC(C)(C)C +CC(C)CC(NC(=O)C(C)C)c1nc2ccccc2[nH]1 +O=C(NCCNc1cnccn1)Nc1ccncc1 +COC(=O)Nc1cc(NC(=O)C2(C#N)CCCC2)ccc1F +COc1cccc(OCC(=O)Nc2ccccc2NC(C)=O)c1 +COc1cccc(OC)c1C(=O)NCC(C)c1c(C)noc1C +CC(C)(C)OC(=O)N1CC(=O)c2sccc2C1 +CC(C)C(NC(=O)C1CCCCC1)C(=O)Nc1ccccn1 +COc1cccc(C(=O)NCC2(c3ccccc3)CCOCC2)c1 +O=C(Cc1ccccc1F)Nc1ccccc1N1CCCC1 +CC(C(=O)N1CCCC1)n1c2ccccc2c2cnn(C)c(=O)c21 +CC(=O)c1ccc(S(=O)(=O)Nc2ccc3c(c2)OCO3)cc1 +CNS(=O)(=O)c1ccc(C)c(C(=O)NCCC2=CCCCC2)c1 +O=C(c1ccnnc1)N1CCN2CC(OCC3CC3)CC2C1 +O=C(NCc1ccccc1Cl)c1ccc2ccccc2n1 +CC(=O)N1CCCC1CCc1ccc(-c2ccccc2F)nn1 +CCOc1cncc(-c2ccc(N3CCCCC3)nc2)n1 +Cc1cc(C)cc(OC(=O)CCc2nc(-c3ccco3)no2)c1 +COc1ccc(NC(=O)Nc2cn(C)c3ccccc23)cc1OC +Cc1cc(C)c(OC(=O)Cn2c(C)csc2=O)c(C)c1 +COc1ccc(C(CCO)NC(=O)c2cccs2)cc1OC +COc1cc(Cc2cc(N)n(CCO)n2)cc(OC)c1OC +O=C(Cc1ccc(N2CCCC2=O)cc1)NCCO +CS(=O)(=O)N(C1CC1)C1CCc2ccccc21 +CCCN(CCO)S(=O)(=O)c1ccccc1F +CC(=O)c1ccccc1NC(=O)c1ccc(F)c(F)c1 +CCC(=O)c1cccc(NC(=O)N2CCOC(C)C2C)c1 +O=C(CN1CCOCC1)NCCNC(=O)c1ccccc1 +CC(=O)Oc1ccc(C2NCCc3c(O)cccc32)cc1 +c1csc(-c2n[nH]cc2CNCCc2nccs2)c1 +CCOC(=O)N1CCN(C(=O)NCCCC(C)C)CC1 +Cc1cccc(NC(=O)c2cn(C)c3ccc(F)cc3c2=O)c1 +Cc1cc(NCC(=O)NC2CC2)ccc1C(=O)OC(C)(C)C +CCc1onc(C)c1NC(=O)N1CCCC1c1ccc2c(c1)OCO2 +CC(C)Oc1ccccc1NC(=O)c1ccc(-n2ccnn2)cc1 +COc1ccc(Cc2nc(C3CC3)c(C(C)=O)s2)cc1 +CCCCN(C)C(=O)NCc1cccnc1OCC +CCC(C)NC(=O)NC(c1ccc(OC)cc1)C1CC1 +Cc1cc(C)nc(-n2nc(C)c3c2NC(=O)CC3c2ccc(O)cc2)n1 +Cc1noc(C)c1-c1ccc(C(=O)N(C)C)s1 +O=C(Cn1ncn2nc(-c3ccccc3)cc2c1=O)N1CCCC1 +COc1cc(NS(=O)(=O)N(C)C(C)C)ccc1NC(C)=O +O=C(CCc1ccccc1)Nc1ncccc1CO +O=C(Cn1nc2c(cc1=O)CCCC2)NCc1nc2ccccc2[nH]1 +CC(c1ccccc1)n1nc(C(N)=O)c2c1CCCC2=O +CCCNc1ccnc(C(=O)N2CCCOCC2)c1 +Cc1cc(C)n(-c2ccc(CC(=O)N(C)c3ccccc3)cc2)n1 +CC(C)Cc1nc(CNc2cc(-n3cnnn3)ccc2F)no1 +CCC(O)Cn1nc(C2CCOCC2)nc1-c1cc(C)ccc1OC +Cc1c(C(C)NC(=O)CCc2n[nH]c(N)n2)cnn1-c1ccccn1 +Cn1ncnc1NC(=O)c1cccnc1OCC(F)F +CCc1onc(C)c1NC(=O)c1ncoc1-c1cccs1 +Cc1nn(C(C)(C)C)cc1C(C)NC(=O)c1ccc2[nH]cnc2c1 +Cc1ccc(C)c2c(C)c(C(=O)N3CCCC3C(N)=O)oc12 +COCC1CN(Cc2ccco2)Cc2cn(CC3CCOCC3)nc21 +O=C(CSc1ncn[nH]1)N1CCN(Cc2ccc(F)cc2)C(=O)C1 +CNc1ncccc1C(=O)N1CCN(Cc2cccc(F)c2)C(=O)C1 +COc1ccc(CC(O)c2cccc(OC)c2)cc1 +CC(C)C1(CNC(=O)c2cnc(C3CCCO3)s2)CC1 +Cc1cccn2c(CNC(=O)c3cccc(Cn4cccn4)c3)cnc12 +CN1C(=O)C2(NC(=O)c3ccccc3N2)c2ccccc21 +N#Cc1ccc(C(=O)NCCc2cccc(O)c2)cc1 +CNS(=O)(=O)c1ccc(C(C)NC(=O)c2cccc(F)c2)cc1 +CCN(c1ccccc1C)S(=O)(=O)c1cn[nH]c1C +CC(NC(=O)c1ccccc1-n1cnnn1)c1ccncc1 +CCCc1cc(C(=O)NC(C)c2c(C)nn(CC)c2C)no1 +NC(=O)c1csc(C(=O)N2CCN(CC3CCCCC3)CC2)c1 +CC(C)(CNC(=O)CCc1ccccc1F)c1ccncc1 +Cc1ccc(C(=O)NC2C3CCOC3C2(C)C)c(=O)[nH]1 +O=C(CCN1CCc2ccccc21)N1CCN(c2ncccn2)CC1 +Cc1ccc(CNc2ncnc(NC(C)C)c2N)cc1 +Cc1ccccc1C1CC1C(=O)Nc1ccc(S(N)(=O)=O)c(C)c1 +CCN(CC)c1ncc(CN2CCOC3(CCC3)C2)s1 +CNC(=O)N1CCc2cc(S(=O)(=O)Nc3cccc(C)c3)ccc21 +Nc1nccnc1C(=O)Nc1ncc(Cc2ccccc2)s1 +COc1ccccc1NC1CCN(C(=O)c2cc[nH]n2)CC1 +CCC(CO)NC(=O)c1ccccc1OC(F)(F)F +Cc1onc(-c2c(Cl)cccc2Cl)c1C(=O)NC(C)C(N)=O +O=C(NCCc1nc2cccnc2n1-c1ccccc1)C1CC1 +O=c1cc(N2CCOCC2)cnn1CC1COc2ccccc2O1 +CCC(C)(CNC(=O)c1c(C)noc1C(C)C)N1CCOCC1 +CCN(Cc1ccc2c(c1)OCO2)c1cccc(N)c1 +Cc1nc(-c2cccs2)sc1CNC(=O)c1snnc1C +O=C1CCCc2c1c(-c1cc(F)cc(F)c1)nn2CCO +Cc1cc(NC(=O)NC(C)(C)CCO)ccc1OC(C)C +COC(=O)CN(C(=O)c1ccccc1Cl)C(C)C +Cc1n[nH]c(C)c1NC(=O)Cc1c(Cl)cccc1Cl +CC(C)NC(=O)Nc1cccc(NC(=O)c2ccccc2)c1 +CCOC(C(=O)NCC(=O)Nc1ccc(F)c(F)c1)c1ccccc1 +COc1ccc(S(=O)(=O)N2CCc3ccccc3C2)cc1 +CCOC(=O)Nc1ccc2c(c1)NC(=O)C(C)(C)CO2 +CC(C)C1COC(=O)N1CC(=O)N(Cc1ccccc1)C1CCCC1 +COc1ccccc1C(=O)Nc1cccc(NC(C)=O)c1C +Cc1ncc(CNC(=O)CCCOc2ccccc2C)s1 +N#Cc1ccc(OCc2ccc(C(=O)NCC(F)(F)F)o2)cc1 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1c(F)cccc1Cl +O=C(Nc1ccn(CC(F)(F)F)n1)c1cccc(-c2ccoc2)c1 +O=C(NCC1(O)CCOc2ccccc21)NC1CCCCCC1 +CN(C)C(=O)C1CCN(C(=O)c2cc(-c3ccccc3)[nH]n2)CC1 +COC(=O)C1CC(O)CN1Cc1ccccc1OC +COC(=O)CCC(=O)Nc1ccn(-c2ncccc2Cl)n1 +Cc1nc2ccccc2n1CCCNC(=O)COc1ccccc1O +CSc1nc(C2CC2)cc(C(=O)N(C)Cc2cnn(C)c2)c1C#N +Cc1cc(O)ccc1C1NCCc2c(F)cccc21 +NC(=O)COc1cccc(C2CC(=O)Nc3ccsc32)c1 +NC(=O)c1n[nH]c2ccc(NC(=O)CCC(=O)c3ccccc3)cc12 +CC(NS(=O)(=O)c1ccccc1)C(=O)Nc1ccc2[nH]ncc2c1 +CNC(=O)c1ccc(OCC(=O)NC2CCCC2)c(N)c1 +Nc1ncc(C(=O)NCCOc2cccc(Cl)c2)cc1Cl +CC1CN(C(=O)c2cccc(NC(=O)C(C)C)c2)CC(C)O1 +Cc1cc(C)c(OS(=O)(=O)c2cn(C)c(=O)n(C)c2=O)c(C)c1 +Cc1nc(NCc2ccco2)sc1C(=O)N(C)C +FC(F)(F)Oc1ccc(CNc2ncn[nH]2)cc1 +O=C(NCc1ccncc1)N(c1ccccc1)c1ccccc1 +Cc1cc(C)c(CNC(=O)N2CCOc3ccccc3C2)c(=O)[nH]1 +CN(C(=O)CCC(C#N)c1cccnc1)c1ccccc1 +CC(C)c1cc(NC(=O)CSc2nncn2C)on1 +COc1ccc(OC)c(-c2c(C)nc(C)nc2N)c1 +Cn1cccc1-c1cnc(CNCc2ccccc2F)s1 +O=C(c1cnc(-c2ccc(Cl)cc2)nc1)N1CCC(CO)C1 +O=C(Cn1nnc(CO)c1C1CCCCC1)Nc1ccccn1 +Cc1ccc(-c2nnc(NC(=O)c3cccs3)o2)cc1 +CCCNc1nnc(-c2cnc(-c3cccnc3)s2)s1 +CCc1ccc(N2CC(C(=O)N(C)CC(O)C3CC3)CC2=O)cc1 +O=C(c1cccs1)C1NCCc2c(Cl)cc(O)cc21 +CCC(=O)NCC(=O)N1CCOC(c2cccc(OC(F)F)c2)C1 +Cc1c(C(=O)N2CCOCC2)sc2nc(C)n(C)c(=O)c12 +Cn1cc(S(=O)(=O)NCc2ccc(F)cc2)c(N)n1 +CCn1cnnc1CNC(=O)CC(NC(C)=O)c1ccc(C)cc1 +CCCCC(=O)N(Cc1cccnc1)c1ccc(F)cc1 +Cc1cc(S(=O)(=O)Nc2ccnn2C)ccc1Br +NC(=O)C1CCN(C(=O)CNC(=O)OCc2ccccc2)CC1 +Cc1ccc(NC(=O)C(C)Sc2nc(N)nc(N)n2)cc1 +COc1ccc2c(c1)nc(C(C)O)n2Cc1cccnc1N +Nc1ccccc1OCCc1nc(-c2cccs2)cs1 +Cc1ccnc(NC(=O)C2CCCN2C(=O)OCC(F)(F)F)c1 +O=C(CNS(=O)(=O)c1cccc(F)c1)Nc1cccnc1 +CCOc1ccc(NC(=O)COc2ccccc2F)cc1 +O=C(N=c1[nH]nc2ccccn12)c1ccc(C(F)(F)F)cc1 +Cc1ccc(C(=O)N(Cc2ccsc2)C2CC2)c(C)c1 +CCC(C)C(=O)N1CCC(Cc2nc3cccnc3n2C)C1 +NC(=O)Cc1ccccc1NC(=O)Cn1nnc2ccccc2c1=O +COc1ccnc(NC(=O)c2ccc3c(c2)NC(=O)CCN3C)c1 +Cc1ccc2c(NC(=O)c3ccc(Cl)cc3)noc2n1 +CCOc1ccc(Cl)cc1NCc1ccc[nH]1 +CCCCn1c(=O)n(C)c(=O)c2[nH]c(NC)nc21 +N#Cc1cc(NC(=O)N2CCc3ccccc3C2)ccc1F +CC(=O)Nc1ccc(C)c(NC(=O)NCc2ccccc2C)c1 +CC1(C)COCCN1C(=O)c1cnn(-c2cccc(Cl)c2)c1 +CCCC(=O)c1ccc(N2CCN(C(=O)C(C)C)CC2)c(F)c1 +Fc1ccc(N2CCN(Cc3cccs3)CC2)cc1 +CC(C)c1ccc(-c2nnn(CC(=O)NCc3cccs3)n2)cc1 +CC(C)C(c1ccccc1Cl)N(C)C(=O)c1ccncc1F +COC(=O)CC1CN(Cc2cc3ccccc3s2)CCO1 +CCc1cc(-c2cnn(CC)c(=O)c2CC#N)ccc1OC +COc1cc(C)c(Cl)c(C)c1-c1c(N)c(C)nn1C +COc1ccc(CCC(=O)Nc2nnc(C(C)C)s2)cc1 +CC(C(=O)NCCS(N)(=O)=O)c1ccc2ccccc2c1 +Cc1csc(NC(=O)CCC(=O)c2ccc3c(c2)OCCO3)n1 +Cc1ccc(F)cc1CNCCc1ccc(O)cc1 +O=C(NCCO)Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1 +O=C(Nc1ccc2c(c1)COC2)N(CC(O)c1ccccc1)C1CC1 +CCCCN1CC(C(=O)Nc2cccc(NC(C)=O)c2)CC1=O +CCCCN(CC)C(=O)Cn1cnc2sc3c(c2c1=O)CCCC3 +CCN(CC)C(=O)c1c(F)c(F)c(F)c(F)c1F +CCc1nn2c(=O)nc(Oc3ccccc3)nc2s1 +O=C(Nc1cccc(C(F)(F)F)c1F)N1CCOCC(CO)C1 +CCCCC1C=CCN1C(=O)c1cccc2ccnn12 +Cc1nc(N2CCOCC2)nc2c1CCN(Cc1cnn(C)c1)CC2 +CC1CCCC(OC(=O)C2CCN(c3ccc4nnnn4n3)CC2)C1 +CC(CNS(=O)(=O)N1CCCC1c1ccco1)N1CCOCC1 +CC(O)CNc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 +COCc1ccccc1C(=O)Nc1ccc(C)c(O)c1 +Cc1oc(-c2cccs2)nc1COc1ccccc1OCCO +CCn1nc(C(=O)NCCCC2CCCC2)c2ccccc2c1=O +CC(=O)NCC(=O)NC(c1ccc(CC(C)C)cc1)C(C)C +COC(=O)c1cccc(C(=O)N(C)C(C)c2cc(F)ccc2F)c1 +CC(C)NC(=O)CN(C)C(=O)C(C)NC(=O)c1ccccc1Cl +CCCc1ncncc1C(=O)N1CC(C)C(C)(O)C1 +COC(=O)C1CN(CCO)CCN1C(=O)OC(C)(C)C +Cc1ccc(C(=O)Nc2cccc(N)c2)cc1Cl +CCC(C)n1c(C)cc(=O)c(O)c1CN(C)Cc1ccccc1 +COc1cccc(-c2n[nH]cc2C(=O)N(C)CCN2CCOCC2)c1 +CCOc1cc(Cl)c(C(=O)c2cccc(N)c2)cc1OCC +CNC(=O)c1cccc(C2CN(c3ncccn3)CCN2C(C)=O)c1 +CCc1onc(C)c1NC(=O)c1ccc(C)c(Oc2ccncc2)c1 +COCCn1cc(NC(=O)CNC(=O)c2cc(F)cc(F)c2)cn1 +Nc1nc(N2CCOCC2)ncc1C(=O)N1CCOCC1 +CCOc1ccc(S(=O)(=O)Nc2ccnn2C(C)C)cc1 +COCCNc1nc(Nc2ccccc2)c2cnn(C)c2n1 +Nc1cccc2c(NCCOCCO)ncc(Br)c12 +O=C(Cc1ccsc1)NCc1ccc(-c2nc(C3CC3)no2)s1 +Cc1cccc(CC(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)c1 +Cc1cc(C)c(S(=O)(=O)c2cccc(C)c2C)c(=O)[nH]1 +COc1ccc(NC(=O)c2ccc(Br)cc2F)cc1O +Cc1nn2c(=O)c3c([nH]c2c1COc1ccccc1)CCCC3 +CCOc1ccccc1OCC(=O)NCc1nc2ccccc2[nH]1 +Cc1n[nH]c(C)c1SCC(=O)Nc1ccccc1C(C)C +Nc1ccc2nc(-c3ccc4c(c3)CCC(=O)N4)cn2c1 +COC(=O)C(C)C(O)c1cc(OC)c(OC)cc1Br +O=C(Nc1ccc(F)cc1F)c1ccncc1F +Cc1ccc(C(=O)N(CC(F)(F)F)C(C)C)c(O)c1 +Cc1ccc(Cl)cc1NC(=O)CSc1nnc(N)n1C +Cn1ccc(S(=O)(=O)NCCNC(=O)c2ccco2)c1 +CN(C)C(=O)c1ccc(OC2CC2)c(OC(C)(C)C)n1 +COCCCN1CC2=C(C1=O)C(c1ccc(C)cc1)NC(=O)N2 +CCC(=O)N1CCc2c(C(=O)NCC(C)C)cccc21 +CN(Cc1ccco1)C(=O)Cn1c(=O)oc2cc(Cl)ccc21 +COC(=O)c1ccc(Cn2cnc3oc(C)c(C)c3c2=O)cc1 +CCCCn1c(=O)c2cccnc2n2c3ccccc3nc12 +COc1ccc(CNC(=O)c2ccc(N)cc2)cc1O +CCOc1ccc(OCC(=O)Oc2ccc3cn[nH]c3c2)cc1 +Cc1ccc(CN(C)C(=O)NCc2ccc(C#N)cc2)s1 +Fc1cccc(CSc2nnc(-c3ccncc3)o2)c1F +CCc1nc(CC(=O)N2CCC(C)CC2)cs1 +CCc1cnc(CN(C)C(=O)NCc2c(C)cc(C)nc2OC)s1 +CCCCN(CCO)C(=O)Nc1cccc(NC(C)=O)c1C +Cc1cc(C(=O)Nc2ccc3c(c2)nc(C(C)(C)C)n3C)[nH]n1 +Cn1cnc(-c2cccc(NC(=O)NC3c4ccccc4CC3O)c2)n1 +c1csc(-c2cnn(CCN3CCOCC3)c2)n1 +CCc1ccc2ncnc(NCCN3CCOCC3)c2c1 +CCN(C(=O)c1cnccn1)C12CC3CC(CC(C3)C1)C2 +COC(=O)c1ccccc1NCCC(O)c1ccccc1 +O=C(CC1C(=O)Nc2ccccc21)NCCc1ccccc1F +Cc1c(CCO)nnn1CC(=O)Nc1nnc(C(C)C)s1 +COC(=O)c1ccc(N2CCN(C(=O)c3cc[nH]n3)CC2)cc1 +CCC1COCCN1C(=O)c1[nH]nc(C2CC2)c1N +Cc1[nH]c(=O)ccc1C(=O)Nc1cccc(-c2ncco2)c1 +Clc1cnc(N2CCC(CN3CCOCC3)CC2)c(Cl)c1 +CCCc1nnc(N2CCOC(c3ccc(F)cc3)C2)o1 +Cc1cc(NC(=O)c2ccc3c(c2)OCO3)n(Cc2ccccc2)n1 +Cc1n[nH]c(C)c1NC(=O)CSc1nc2ccccc2o1 +COC(=O)c1ccc(NC(=O)c2cccs2)s1 +COc1ccc(Br)c(-c2ncc[nH]2)c1F +Cc1c(C)n(-c2cccnc2)c2ncnc(NCCCn3ccnc3)c12 +CC(C)(C)C(O)CN1CCN(C(=O)CN2CCCC2=O)CC1 +O=C(c1cccc(Cl)c1)N(CCc1cscn1)Cc1ccco1 +COCCNC(=O)c1ccccc1C(=O)c1ccc(C)cc1 +CC(=O)N1CCCC1C(=O)Nc1c(C)cc(C)cc1C +CN(C)c1nc(N)nc(COc2cccc(Br)c2)n1 +NC(=O)c1cnc(NCc2cccs2)c(Cl)c1 +CC(=O)NCc1c(C)c(C)c(CNC(C)=O)c(C)c1C +COC(C(=O)Nc1nccn(C)c1=O)c1ccccc1 +CC(C)N(C(=O)C1CCOc2ccccc21)C1CCOCC1 +O=C(OCc1nn(-c2ccc(F)cc2)c2c1CCC2)C1COCCO1 +O=C(NCc1ccccn1)c1n[nH]c2cc(Cl)ccc12 +Cc1ccc(Cl)cc1-c1cccc2nc(N)nn12 +Cc1nc(C(C)(C)NCCc2scnc2C)sc1C +COc1cc(OC)cc(C(=O)NCC(=O)NC(C)c2ccccc2)c1 +O=C(Nc1nc(-c2cc(F)ccc2F)cs1)c1ccco1 +CCCNC(=O)c1ccccc1NC(=O)Cc1ccc(F)cc1 +Cc1cc(C)n(CCNC(=O)c2nc(-c3cnccn3)no2)n1 +CC(C)c1ocnc1C(=O)N(C)c1ccc(Cl)cn1 +CCOC(CC)C(=O)NC1CCCc2c1cnn2Cc1ccccc1 +Cc1cc(CN2CCN(C(=O)c3cc(C)oc3C)CC2)c(C)o1 +CC(Cc1cccc(F)c1)C(=O)N1CCCC1c1ccc[nH]1 +COc1ccc(C(CC(=O)NCc2cccnc2)NC(C)=O)cc1 +CCCn1ccc2ccc(NC(=O)NCC(=O)N3CCCC3)cc21 +CCn1cnnc1CCNc1nc(C)nc2c1cnn2C +CC(=O)Nc1ccnn1C1CCN(C(=O)Cc2ccc(F)cc2)CC1 +CCCCc1ccc(NC(=O)c2nc3nccc(C)n3n2)cc1 +CCCN(C)C(=O)CC(NC(N)=O)c1cccs1 +Cc1cnc(NC(=O)c2coc(NC(=O)c3ccccc3)n2)s1 +N#Cc1ccc(OC(=O)CCn2ncc(=O)c3ccccc32)cc1 +Cc1cccc(CN(C(=O)Cc2cn3ccsc3n2)C2CC2)c1 +O=C(Cc1cccs1)NCc1cccn1Cc1ccccc1 +Cc1occc1-c1nnc(SCC(=O)N(C)C2CCCCC2)n1C +Cc1ccc(-c2nc3ncccc3o2)cc1-n1cnnc1 +NC(=O)Nc1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +COc1cc(N)c(OC)c(S(=O)(=O)NC(C)(C)C)c1 +CN(C)S(=O)(=O)c1ccc(-c2ccc(F)c(O)c2)cc1 +COc1ccc(CC(=O)N2CCC(O)C2Cc2cccnc2)cc1 +CCc1ccc(-c2c(-c3ccccc3)ncn2Cc2nnc(C)o2)nc1 +NC(=O)COc1ccc(NC(=O)NC2CCCC2)cc1 +CCCNC(=O)C1CN(C(=O)OC(C)(C)C)c2ccccc2O1 +CC(C)(CNC(=O)c1ccccn1)c1ccc2c(c1)OCO2 +CN(C(=O)CCn1cc(Br)ccc1=O)C1CC1 +CCN(CC(C)C#N)C(=O)CNc1cccc(N2CCOC2=O)c1C +CCC(C)CN(C)S(=O)(=O)c1ccc(C#N)cc1 +CC(Sc1nnc(-c2ccco2)o1)c1nnc(-c2cccs2)o1 +CC1(C)Oc2cc(S(=O)(=O)NC3CCCC3)ccc2NC1=O +FC(F)(F)Oc1ccc2c(c1)C(c1ccncc1)NCC2 +O=C(Cn1ccc(=O)cc1)NCc1ccc2sccc2c1 +O=C(Cc1cc(-c2ccc3c(c2)OCO3)on1)NCc1cccs1 +O=C(NCc1cc(=O)[nH]c2ccccc12)c1ccc(F)nc1 +Cc1nc(CC(=O)N2CCC(CCn3cccn3)CC2)cs1 +Cc1ccc2oc(C(=O)NCCS(=O)(=O)N3CCCC3)cc2c1 +CCn1cnnc1CNC(=O)C1CC(=O)N(c2ccc(Cl)cc2)C1 +CCOCCCNC(=O)C1(C)CC1(Cl)Cl +Cc1cc(NC(=O)NCCO)ccc1Br +COCCn1cc(C(=O)N2CCN(C(C)=O)CC2)c2ccccc21 +CCN(Cc1ccc2c(c1)OCCO2)C(=O)CN1CC(C)OC(C)C1 +Cc1cc(C)n(-c2ccc(=O)n(CC(=O)NCc3cccs3)n2)n1 +O=C(NCCOc1cccc(Br)c1)NCC1CCCO1 +O=C(COc1ccc(F)cc1)Nc1ccc2c(c1)OCCO2 +CC(C)(C)NC(=O)CSc1nc(CC2CCCC2)n[nH]1 +CCN(CC(=O)N(C)C)C(=O)c1c(C)cccc1N +Cc1ccc(NC(=O)NCc2ccco2)cc1S(C)(=O)=O +CC(C)CCn1c(CCNC(=O)C2CCCO2)nc2ccccc21 +COc1cc(N)ccc1NC(=O)COc1cccc(C#N)c1 +C=C(C)Cn1c(=O)c2c(nc3n(C(C)CC)c(C)c(C)n23)n(C)c1=O +N#CC1C(=O)Nc2nn(-c3ccccc3)c(O)c2C1c1ccco1 +Cc1nn(CC(=O)N(C)C)c(C)c1S(=O)(=O)N1CCOCC1 +COCCOc1ccccc1C1Nc2cccc(C)c2C(=O)N1C +CC1CCC(C(N)=O)CN1C(=O)c1sc2sccc2c1Cl +Cc1ccn2cc(C(=O)Nc3c(C)cccc3O)nc2c1 +COc1cc2c(cc1OC(C)C)N=CC(C#N)C2=O +O=C(CCc1ccc(F)cc1)NCc1cscn1 +CCOc1cc(NC(=O)c2cc[nH]n2)ccc1OC +O=C1CCCCN1C(c1ccccc1)n1nnc2ccccc21 +O=C(Nc1cccc(-n2cnnc2)c1)c1cccc(F)c1 +Cc1cc2ncn(CC(=O)Nc3ccccc3C#N)c2cc1C +Cc1oc(-c2ccno2)cc1S(=O)(=O)NCCC1=CCCCC1 +CC(C(=O)N=c1[nH]c2ccccc2[nH]1)S(=O)(=O)c1ccc(F)cc1 +COc1cccc2c1CCC2NC(=O)N1CC(C)OC(C)C1 +COc1ccc(C(=O)Cc2nc(C)cs2)cc1N +CCOC(=O)c1cc(-c2ccc(O)cc2)nn1-c1ccccn1 +O=C(NC1(c2cccc(Cl)c2)CC1)c1cnc2ccccn2c1=O +COc1ccc(CCCNC(=O)NCc2sc(C)nc2C)cc1 +CCCc1noc(C(C)n2c(C)nnc2-c2cccc(C#N)c2)n1 +Cc1ccnc2nc(COc3ccccc3Cl)[nH]c12 +Cc1c(C(C)NC(=O)c2cc3ccccc3c(=O)[nH]2)cnn1C +CCCCC(NC(N)=O)C(=O)N1CCN(C)CC1 +CC(Sc1ccccc1)C(=O)Oc1cccc(N2CCCC2=O)c1 +O=C(C1CCCO1)N1CCCC(c2cc3cccnc3c(=O)[nH]2)C1 +O=C(Nc1cccc(C#Cc2ccccn2)c1)c1cn2cccnc2n1 +O=C(COc1ccccc1Cl)N1CCOCC1C1CC1 +OC(CNCc1cccnc1)c1cc(F)ccc1F +O=S(c1c(O)cccc1O)c1c(O)cccc1O +CNC(=O)c1cccc(NC(=O)Cc2coc3cc4c(cc23)CCC4)c1 +CCn1cnnc1CNC(=O)Cc1coc(-c2ccccc2)n1 +COC(=O)C(C)NCc1nnnn1-c1ccccc1 +CC(NC(=O)C1CC(=O)N(c2ccccc2Cl)C1)c1cccnc1 +O=C(CCCc1nc2ccccc2s1)NC1CCOC1=O +CCN1CCc2nc(NC(=O)c3ccncc3)sc2C1 +CC(C)c1cc(C(=O)NCCCn2ccnc2)cs1 +COc1ccc(S(=O)(=O)NCc2ncccc2C)c(C)c1C +CC(C)n1cc(CCC(=O)Nc2ccc(C(N)=O)cc2)c2ccccc21 +CCNc1ncc(S(=O)(=O)NCC(=O)NC)cn1 +CCCNC(=O)CSc1ccc(-n2nc3c(c2C)CCC3)nn1 +CNC(=O)c1ccc(NC(=O)c2ccccc2OCCOC)cc1 +CCc1ccc(CNC(=O)c2ccc(-n3cncn3)nc2)s1 +Cn1cnnc1SCCOc1c(Cl)cccc1Cl +c1ccc2c3c(N4CCOCC4)[nH]n4cnnc4c-3nc2c1 +O=C(NC1CCCOc2ccccc21)N1CCc2cc(F)ccc2C1 +O=C(NCc1cccc(NC(=O)C2CC2)c1)c1ccc(=O)[nH]n1 +Cc1cc(C)n(CC(=O)c2ccc(C(C)C)cc2)n1 +CCOC(=O)CN(CC)C(=O)c1c(F)cccc1F +CC(=O)Nc1cccc(NC(=O)C2CC=CCC2)c1 +CC(OC(=O)c1cc(-c2ccccn2)nc2ccccc12)C(N)=O +Fc1ccc(Cn2nc(C3CC3)nc2CCCc2cn[nH]c2)cc1 +CCOc1ccc(CCC(=O)N2CCN(CCO)CC2)cc1N +COc1cc(CNCCc2ccccn2)cc(Cl)c1OC +O=C(NCc1ccnc(-n2cccn2)c1)c1ccc2ccccc2c1O +C#CCCN1CCN(C(=O)c2nn(-c3ccccc3)cc2OC)CC1 +Cc1cc(C)c2c(c1)N(Cc1nnc(C(C)C)o1)CCC2 +Nc1ncnc2c1nc(-c1ccccc1)n2C1OC(CO)C(O)C1O +CCc1nn(C)c(CC)c1CNCC(O)c1cccs1 +O=C(Nc1nc(Cc2ccc(F)cc2)n[nH]1)c1ccc(Cl)cn1 +COc1cccc(-c2nnn(CC(=O)NCc3ccc(C)cc3)n2)c1 +O=C1CN(C(=O)c2cc(=O)c(OCc3ccccc3F)co2)CCN1 +COCCCn1c(SCC(F)(F)F)nc2ccccc2c1=O +CC(C)C(=O)CN1CCN(C(=O)OC(C)(C)C)CC1 +O=C(Nc1cccc(Cl)c1)NC1C2CCC(C2)C1CO +CCCCN(CC(N)=O)c1ccccc1C(C)O +CC(=O)Nc1cccc(-c2nnc(-c3ccccc3)o2)c1 +CCc1csc(C2CCCN(C(=O)c3ccc[nH]c3=O)C2)n1 +CCc1cccc(NC(=O)C(Cc2ccccc2)NC(N)=O)c1 +COc1ccc(OC(C)C(=O)Nc2cccc(NC(C)=O)c2)cc1 +O=C(CSc1nncn1-c1ccccc1)NCc1ccco1 +COc1cc(OC)c2c(c1)C(c1cc(=O)cc[nH]1)NCC2 +COc1ccc(CNC(=O)c2cn3ccc(C)cc3n2)c(OC)c1 +Cc1nc(C)c(C(=O)NCCNc2ncc(Cl)cc2Cl)s1 +C#CCOc1ccccc1C(C)OC(=O)c1cn(C)nc1C +Cc1nnc(NC(=O)COC2CCCCC2)s1 +Cc1ccc(NC(=O)c2ccccc2Cl)c(OCC(=O)N(C)C)c1 +Cc1ccc(-n2nc(C(=O)N(C)C(C)C)nc2Cc2ccccc2)cc1 +CN(C)c1nc(COc2cccc(-n3ccnc3)c2)ns1 +O=C(NCCNC(=O)c1cnn[nH]1)c1ccc(F)cc1 +CSc1ccc(Cc2nnc(NC(=O)c3snnc3C)o2)cc1 +COC(=O)c1cc(Br)ccc1NC(=O)C(C)C +c1ccc(-n2ccnc2-c2ccncc2)c(CN2CCOCC2)c1 +COc1cc(F)c(NC(=O)NCc2nc(C)sc2C)cc1OC +COCc1nc(C)c(C(=O)Nc2nc3c(s2)C(=O)CCC3)s1 +CCN(Cc1ccc(O)cc1)C(=O)NCCOC +CC(C)C1CCCCN1C(=O)c1cncc(Br)c1 +COc1ccc(NC(=O)c2ccc(Cl)c(N)c2)cn1 +O=C(Cn1c(=O)[nH]c2ccccc21)Nc1nncs1 +COc1ccc2ccccc2c1CNc1ccn(CC(F)F)n1 +Cc1nc(NC2CC2)cc(-c2ccc(C)c(C)c2)n1 +Cc1nccc(-c2cccc(-n3ccnc3-c3ccco3)c2)n1 +CNc1nc(-c2cc3c(cc2F)NC(=O)CC3)cs1 +CC1(C)C(NC(=O)COc2cccc(C(N)=O)c2)C2CCOC21 +CCN(Cc1c(F)cccc1F)C(=O)Nc1cnccc1C +c1ccc(NCc2ccc(-n3cncn3)cc2)cc1 +Cc1cccc(OCCNS(=O)(=O)c2cccc(C#N)c2)c1 +Cc1oc(C(=O)N(C)Cc2ccc(Cl)cc2)cc1S(N)(=O)=O +Cc1cc(C(=O)Nc2nc(-c3ccccc3)c(C)s2)no1 +O=S(=O)(NCc1ccc(F)cc1)c1ccccc1C(F)(F)F +CCc1nc(CCNC(=O)Nc2cc(C(N)=O)sc2C)cs1 +COc1ccc(NC(=O)NC2CC(=O)N(c3ccc(F)cc3)C2)cc1 +CC(=O)Nc1cc(S(=O)(=O)N(C)CC(C)(C)C)ccc1F +Cc1cc2c(nc1C)sc1c(NCCO)ncnc12 +CC(=O)Nc1cc(C(=O)Nc2ccccc2)ccc1Cl +Cc1c(C(=O)OC(C)c2ccccn2)nnn1-c1cccc(Cl)c1 +Cn1c(CN2CCCC2c2cccs2)cc(=O)n(C)c1=O +CCCNC(=O)CN1CC(CC)Oc2cccc(N)c21 +CC(C)(CNC(=O)c1cncc(F)c1)CNC(=O)c1cncc(F)c1 +COc1ccc(S(=O)(=O)N2CCN(c3ccc(C)nn3)CC2)cc1 +Cc1ccc(CC(=O)Nc2ccc3ccccc3n2)s1 +COc1cccc(CC(=O)Nn2c(C)ccc2C)c1 +Cn1cnnc1C1CCCN(C(=O)COc2ccc(Cl)cc2)C1 +CCC(CO)Nc1ccc(NC(=O)c2ccc(C)c(C)c2)cn1 +CCNC(=O)NCCOC(=O)c1ccc2nncn2c1 +CCn1c(=O)c2nscc2n(CC(=O)Nc2ccccc2F)c1=O +CN(CC(=O)Nc1ccc(F)cc1)C(=O)c1ccsc1 +O=C(Cn1cnnn1)Nc1ccccc1C(=O)N1CCCCC1 +CCOc1ccc(OS(=O)(=O)c2cn(C)c(=O)n(C)c2=O)cc1 +Cc1ccc(-c2noc(Cn3ccccc3=O)n2)cc1 +COc1ccc2c(c1OC)C(=O)N1c3ccccc3SC21 +CN(Cc1ccncc1)C(=O)Nc1cccc(N)c1 +CCC1C(=O)NCCN1C(=O)c1csc(-c2ccccc2OC)n1 +CCCc1nnc2sc(C3(c4ccccc4)CC3)nn12 +CCOC(=O)c1cnn(C2CCCN(C(=O)NCC3(CC)CC3)C2)c1 +CCN(C(=O)CCn1c(=O)oc2ccccc21)c1ccc(F)cc1 +Cn1cnnc1C1CCCN(C(=O)CN2CCCCCC2=O)C1 +Cc1cc(C(=O)N2CCC(c3nc(C(C)C)no3)CC2)c(C)o1 +C=CCNc1nc(C(F)(F)F)nc2cc(OC)ccc12 +Cc1ccc(CN2CC(c3nc(-c4cnccn4)no3)C2)o1 +O=C(Cc1cn2ccsc2n1)Nc1ccc2oc(=O)ccc2c1 +CC(NC(N)=O)C(=O)NC(C)C(=O)NCC(F)(F)F +NC(=O)C(c1ccccc1)N1CCC(C(F)(F)F)(C(F)(F)F)C1 +COc1ccc(CNC(=O)c2cc(C)n3nc(C)cc3n2)c(F)c1F +CCOc1ccc(-c2cnnn2Cc2ccc(C#N)cc2)cc1 +CCOc1ccc(N2CC(NC(=O)CC)CC2=O)cc1 +CC(C)(C)CC(=O)NCCS(=O)(=O)c1ccccc1 +CCC(C)Oc1ccc(NC(=O)C(C)(C)C#N)cc1 +CCCN(CCC)c1nc2ccccc2c2nc(C)nn12 +CC1CCCC(CNC(=O)C2CCCN(C(=O)C3CC3)C2)C1 +COc1cccc(CNC(=O)Cc2c3cccccc-3[nH]c2=O)c1 +O=C(Nc1cccnc1)C1CCCN1C(=O)c1cc2scnc2[nH]1 +CCCC1CN(c2ncnc3ccsc23)CC1NS(C)(=O)=O +Cc1sc(-c2ccco2)nc1C(=O)N(C)Cc1ccc(F)cc1F +COC1CCCC1NS(=O)(=O)c1ccccc1Br +C#CCN1CCC(C(=O)Nc2cccc3cn[nH]c23)CC1 +CCc1ccc(O)c(C(=O)N2CCN(c3ccc(C#N)cn3)CC2)c1 +CC(COCC(F)(F)F)NC(=O)c1ccnc(-n2cncn2)c1 +COCC(C)NC(=O)c1coc(COc2ccc(F)cc2)n1 +CCc1nnc(NC(=O)NC(C)C(O)c2ccc(OC)cc2)s1 +CCC1COCCN1Cc1c[nH]nc1-c1ccc2c(c1)OCCO2 +CCCN(CCC)C(=O)c1cc(Cl)c2c(c1)OCCO2 +CC(N(C)S(=O)(=O)c1cc(Br)ccc1N)C(C)(C)C +Nc1c(Cl)ccn2c(-c3cccs3)nnc12 +Cc1nnc(S(=O)(=O)Cc2ccccc2)n1Cc1ccccc1 +CCOc1nc(CC)nc(NCc2ccccc2F)c1N +COc1cccc(C(C)Nc2cccc(CO)c2)c1 +O=C(CSc1ccc(F)cc1F)Nc1cccc(CO)c1 +N#Cc1ccc(COC(=O)CCC(=O)c2ccc(F)c(F)c2)cc1 +O=C(CNC(=O)Nc1ccc(Cl)cc1F)Nc1ccccc1 +O=C(CSc1ncnc2nc[nH]c12)c1c[nH]c2ccccc12 +COc1ccc(OCCc2ncc(C#N)s2)cc1 +Cc1ccccc1-n1c(SCCCO)nc2ccccc2c1=O +Cn1c(SCC(=O)N2CCc3ccccc3C2)nc2ccccc21 +Cc1ncc(C(=O)NCc2nncn2CCc2ccccc2)c(=O)[nH]1 +CC(C)COC(=O)N1CCCC1C(=O)NC1CC1 +CCCCCNC(=O)NC1(CCO)CCCCC1 +C=CCNC(=O)c1cc2cc(OC)ccc2oc1=O +CC#CC1NCCc2cc(Cl)c(O)c(OC)c21 +CCOC(=O)Cc1c(C)nc2ncnn2c1N1CCN(C(C)=O)CC1 +O=C(NCC1CCOCC1)C1CCN(c2cccnn2)C1 +COCCNC(=O)c1cc(-c2ccc(OC)cc2)n(C)n1 +Cc1cc(C)n(-c2cc(C)c3c(C)nn(C)c3n2)n1 +Cc1noc(C)c1CN(C)CC1COc2ccccc2O1 +CCCCCNC(=O)C1CCN(C(=O)Nc2cccnc2)CC1 +Cc1oc(-c2ccco2)nc1CN1CC(C)OC(C)C1 +CCc1ccc(S(=O)(=O)N2CCC(c3ccncc3)CC2)cc1 +Cc1ccc(C)c(OCC(=O)NC(C)c2ccncc2)c1 +O=C(Nc1nc(-c2cccc(Cl)c2)ns1)C1CCCO1 +COC(=O)c1cccc(NS(=O)(=O)c2ccccc2C#N)c1 +Cc1noc(C)c1CN(C)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +CC(NC(=O)C1CCCN(c2cnccn2)C1)c1ccncc1 +CN(CC(=O)Nc1cccnc1)C(=O)c1ccco1 +Cc1cccnc1NC(=O)C1CCCN(C(=O)NC2CC2)C1 +COC(=O)N(C)c1ccc(NC(C)C(=O)NCC(C)C)cc1 +CCC(OC)C(=O)N(CC(N)=O)Cc1ccc(Br)cc1 +CCOC(=O)C1(O)CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +CC(NC(=O)c1cc2c(s1)CCCC2)c1ccccn1 +CC(=O)Nc1ccc(SCC(=O)Nc2cccc(F)c2)nn1 +COc1ccc(NC(=O)c2ccno2)c2ccccc12 +Cc1cnc(Cn2nnc(Cc3ccccc3Br)n2)o1 +Cc1nc(NC(=O)c2cn(C)nc2C(C)(C)C)n[nH]1 +CN(C(=O)c1cccc(F)c1)C1CCCc2ccccc21 +COc1ccc(NC(=O)C(C)OCc2ccccc2)cn1 +CCCOc1cc(NCc2ccccc2)nc(C)n1 +CC(C)C(C)(C#N)NC(=O)Cn1c(C(F)(F)F)nc2ccccc21 +Cc1ccc2nc(CNCc3cc(=O)c4cccc(F)c4[nH]3)[nH]c2c1 +COCC(=O)N1CCC(c2nnc(C(C)C)o2)CC1 +CCOc1ccc2c(c1)C(c1cccnc1F)NCC2 +CNC(=O)NCC(=O)N(CCOC)Cc1ccc(C#N)cc1 +O=C(CCc1nc(-c2cccs2)no1)NC1CCCCC1 +COc1ccc(-c2c(C)sc3ncnc(NC(C)(C)CO)c23)cc1 +COc1ccc(-c2nnsc2C(=O)NCc2ccccc2F)cc1 +COc1ccc(-c2nnc(SCC(=O)N(C)C)o2)cc1 +Cc1cc(C)c(OCC(CC#N)N2CCOCC2)cc1C +Cn1cc(C(=O)N2CCc3ccc(F)cc3C2)c(C(C)(C)C)n1 +N#Cc1ccc(-c2noc(C3(Cc4ccccc4)CC3)n2)nc1 +COc1ccc(N(C)C(=O)c2ccccc2N)cc1OC +Cc1c(NCC(C)(C)C)cccc1C(=O)NCc1cnn(C)c1C +Cc1cc(S(=O)(=O)Nc2ccccn2)c(C)cc1Br +CC(=O)NC(C(=O)NC(Cc1ccccc1)C1CC1)C1CCCC1 +Cc1nnc2n1CC(Nc1ncnc3sccc13)CC2 +CCc1nnc(NC(=O)c2ccc(NC3CC3)nc2)s1 +Cn1ccc2c(C(=O)N3CCN(C(=O)c4ccco4)CC3)cccc21 +CCOc1ccc(OCCNC(=O)c2ccc(F)cc2F)cc1 +CC(C)(C)NC(=O)N1CCc2nnc(-c3ccccn3)n2CC1 +O=C1C(NCc2nnc3n2CCCC3)CCN1c1ccc(Cl)cc1 +CCC1CCCCN1C(=O)CCc1ccc(O)c(N)c1 +CC=CCCNC(=O)Cc1csc(Cc2ccccc2)n1 +CCN(CC)c1ccc(NC(=O)c2ccc3c(c2)nnn3C)cn1 +Cc1nc2ccc(Cl)cc2n1CC1CCCO1 +CN(C)S(=O)(=O)NCCC12CC3CC(CC(C3)C1)C2 +CC(=O)Nc1cc(C(=O)NCCO)nn1-c1ccccc1 +Cc1cccc(C)c1NC(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +CCc1sc(C(=O)Nc2ccc(S(C)(=O)=O)cc2C)cc1C +COc1cc(C)c(NC(=O)c2cc3ccccc3oc2=O)cc1OC +CS(=O)(=O)NCc1ccccc1OC(F)(F)F +Cc1cc(NC(=O)c2scnc2C)ccc1C(=O)N(C)C +CN(CC(=O)Nc1ccc(C(N)=O)cc1)S(C)(=O)=O +CC(C)Oc1cccc(-c2ccc(CO)c(=O)n2C(C)C)c1 +CC(C)Oc1cc(C(=O)Nc2nccs2)cc2occc12 +CCC(CC)n1nc(C)cc1NC(=O)c1cnoc1C1CC1 +Cc1cnc(NC(=O)CNC(=O)c2ccc(Cl)cc2Cl)s1 +CCn1nc(C)c2nnn(CC(=O)NCc3ccccc3)c(=O)c21 +Cc1ccsc1C1CCN(C(=O)CCC(F)(F)F)CC1O +Cc1cccc(NC(=O)N(C)C(C)c2ccc(S(N)(=O)=O)cc2)c1 +Cc1csc(COc2ccc(N(C)C(N)=O)cc2)n1 +CCCc1nc2sc(C(=O)OC)c(C)c2c(=O)[nH]1 +Cc1cc(C2CCC2)nc(N(C)Cc2noc(C(C)C)n2)n1 +Cc1ccc(CN(Cc2ccc(C#N)o2)C(C)C)o1 +CC(CC#N)N(C)C(=O)CNC(=O)OC(C)(C)C +COC(=O)c1cc(-c2ccc(F)cc2)nn1CCO +O=C(Nc1ccccc1O)c1c[nH]nc1-c1ccc2c(c1)OCCO2 +CC(C)N1CCn2c(nc3cc(NC(=O)C(C)(C)C)ccc32)C1 +Cc1c(NCC(=O)NCCC(C)C)cccc1C(N)=O +CSc1nc(NCCO)cc(-c2ccccc2)n1 +O=S(Cc1cccc(NCc2cscn2)c1)c1ccccc1 +COc1cccc(S(=O)(=O)CC(=O)NCCc2ccccc2)c1 +Cc1cc(N(C)Cc2noc(C3CCC3)n2)n2nc(C)c(C)c2n1 +COc1ccc2nc(C(=O)Nc3ccccc3)n(C)c2c1 +CCOC(=O)C(C#N)c1c(F)c(F)cc(F)c1F +O=C(Nc1ccc2c(c1)N(C(=O)C1CC1)CC2)c1ccc(F)cc1 +CC(=O)c1c(SCC(=O)Nc2cccc(C)c2C)nc(=O)[nH]c1C +CC(=O)Nc1cc(C(=O)OC2CCCC2)ccc1F +CCn1cc(C(=O)N(Cc2ccncc2)C2CC2)cn1 +Cc1cc(NC(=O)NC2CC2)ccc1Oc1cccnc1 +CC1Cc2ccccc2N1C(=O)c1cc(-c2cccnc2)on1 +O=C1CC(NC(=O)C23CC4CC(CC(C4)C2)C3)CN1C1CC1 +CCc1ccccc1C(=O)N1CC2CC(C1)C1CCCC(=O)N1C2 +NC(=O)C1CCN(C(=O)CCOc2ccc(F)c(Cl)c2)CC1 +CC1CCCN(S(=O)(=O)NCc2cccc(O)c2)C1 +Cc1cc(F)c2c(c1)CCCN2C(=O)c1ccncc1 +Cc1nnc(SCCCOc2cccc3ccccc23)n1N +O=C(Cc1coc2cc(O)ccc12)OCCOc1ccccc1F +Cc1cc(C(=O)NCC(O)c2cccc(OC(F)F)c2)ncn1 +O=C(Cc1c(F)cccc1Cl)NC1(c2ncon2)CCOCC1 +COCCNC(=O)COc1ncnc2sc3c(c12)CCCC3 +Cn1c(C(C#N)C(=O)C2CC(=O)N(CC3CC3)C2)nc2ccccc21 +CC(C)(C)n1cc(NC(=O)CCNS(C)(=O)=O)cn1 +COc1cccc(-c2nnn(Cc3nc(C4CC4)no3)n2)c1 +O=C(Nc1ccc(F)cc1)c1ccc2snnc2c1 +CC(=O)N1CCCc2cc(NC(=O)c3ccccc3C)ccc21 +CCC(CO)NC(=O)c1nc2c(s1)CCCN2C(=O)C1CC1 +O=C(c1ccoc1)N1CCC(O)(C(F)(F)F)CC1 +Cc1ccccc1CS(=O)(=O)NCC(=O)N1CCc2ccccc21 +Cc1nccc(CNc2ccccc2S(N)(=O)=O)n1 +COC(=O)c1ccccc1NC(=O)CCc1nc(-c2ccco2)no1 +CC(NC(=O)N(C)Cc1c(F)cccc1Cl)c1nncn1C +CN(C)c1cccc(C(=O)Nc2cccc(-n3cnnc3)c2)c1 +O=C(Nc1cccc2cccnc12)c1cnc2sccn2c1=O +CCCOc1ccc(S(=O)(=O)NC(C)C)cc1C +Cc1ccc(CC(=O)NCC2(C(N)=O)CCOCC2)s1 +Nc1c(-c2cc(F)ccc2F)nc2ccc(F)cn12 +COC(=O)N(C)CC(=O)Nc1cccc(Cl)c1N(C)C +CCN(C(=O)c1cn[nH]n1)C(C)c1ccc(F)cc1 +Cc1ccn2c(=O)nc(SCC(=O)Nc3ccccc3)nc2c1 +CNC(=O)c1ccc(COc2cc(C)ccc2C)o1 +N#Cc1ccc(N2CCC(C(=O)N3CCCC(C(N)=O)C3)CC2)nc1 +Cc1cc(C)n(C(=O)Nc2cc(F)ccc2F)n1 +CNC(=O)c1ccc(NC(=O)C(C)Sc2ccccc2)cc1Cl +Cc1ccc(N2CC(C(=O)N3CCCCC3)CC2=O)cc1 +CC(C)c1nc(CC(=O)OCC(=O)N2CCOCC2)cs1 +COCc1ccc(CNC(=O)N2CCN(C(=O)C(C)(C)C)CC2)cc1 +Cc1cccn2c(=O)c(C(=O)NCc3ccc(F)cc3)cnc12 +CCN(C(=O)c1cc2n(n1)CCCO2)c1cccc(C)c1 +Cc1cc(C)c(S(=O)(=O)Nc2ncccc2C)cc1C +C#CCN(Cc1ccco1)S(=O)(=O)Cc1ccccc1 +Cc1nc(CN(C(=O)C2CC3CCC2O3)c2ccc(F)cc2)cs1 +Cc1cc(C)cc(C(=O)N2CCC(C(=O)Nc3nccs3)CC2)c1 +Nc1cc2c(cc1NC(=O)c1ccccc1)CCCC2 +COc1ccc2c(c1)NC(C)C(=O)N2Cc1cccc(C#N)c1 +O=C(CCCc1nc2ccccc2s1)Nc1ncccc1O +Cn1ccc(NC(=O)c2cc3c(=O)c4ccccc4oc3o2)n1 +Cc1nc(-c2cccc(C(=O)N3CC(=O)Nc4ccccc43)c2)cs1 +O=C(NCCNc1cc(-n2cccc2)ncn1)C1CCCC1 +COc1ccc(-c2cc(N)ccc2C)c(OC)c1OC +NC(=O)c1ccc(Cl)cc1NC(=O)COc1ccccc1F +Cc1ccc(Cl)cc1NC(=O)CC(NC(N)=O)c1ccccc1 +CNC(=O)C1CCCN1c1nc2sccn2c1CO +O=C(NCC#Cc1ccc(N2CCOC2=O)cc1)c1ccccc1F +CC(C)(C)C(=O)Nc1cccc(N2CCNC2=O)c1 +CC(C)(C)c1cc2[nH]c3c(c(=O)n2n1)CN(Cc1ccccn1)CC3 +CCn1nc(C)c2ncnc(NCc3ccccn3)c21 +Cc1cc(CNc2ncnc3[nH]ncc23)ccc1F +O=C(Cc1cccs1)NCC(=O)c1ccc2c(c1)OCO2 +Cc1cnc(C(=O)Nc2ccc(OC(F)F)c(Cl)c2)cn1 +CC(C)=CC1C(C(=O)NC2CCCCNC2=O)C1(C)C +CC(C)CNc1cnn(-c2ccc(C(F)(F)F)cn2)c(=O)c1Cl +CC(=O)NC(C(=O)N=c1[nH]nc2ccccn12)C(C)C +CCCC(=O)N1CCCCC1c1nc2c(c(=O)[nH]1)CCN(C(C)=O)C2 +CS(=O)(=O)NC1CCCN(C(=O)c2cccs2)C1 +COc1ccccc1NC(=O)Cn1cnc2cc(F)ccc2c1=O +Cc1ccsc1C(=O)NCc1cccnc1-n1ccnc1 +CCOC(=O)COCCn1cnc2c(oc3ccccc32)c1=O +COC(=O)c1cccc(C(=O)NCc2cnn(Cc3ccccc3)c2)c1 +Cc1nc(N)ncc1C(=O)N1CCN(Cc2ccccc2CO)CC1 +CC(C)CCC(=O)N1CCN(C(=O)Cc2ccccc2F)CC1 +CCOCC(=O)Nc1cnn(-c2ccccc2F)c1 +N#Cc1ccc(CN2C(=O)c3ccccc3S2(=O)=O)cc1 +Cc1ccc(O)c(NC(=O)c2cnc3ccccn3c2=O)c1 +CCOc1cccc(C(C)NC(=O)CCc2c(C)[nH]c(=O)[nH]c2=O)c1 +Cc1nc2c(cc(OCC(=O)N(C)CC(C)C)c3ccsc32)s1 +CC(=O)NC(C)C1NCCc2c(F)cc(F)c(F)c21 +CC(=O)Nc1cccc(NC(=O)c2ccc(-n3cccc3)cc2)c1 +Cc1nn(C)c2ncc(C(=O)Nc3ccc4c(c3)OCCCO4)cc12 +CC(NC(=O)c1noc2c1COc1ccccc1-2)c1ccccc1 +CCc1nc2cc(NC(=O)C(C)N3CCOCC3)ccc2n1CC +CCN(CC)C(=O)CSc1nnc(Cc2csc(C)n2)o1 +Cc1c(Cl)cccc1NC(=O)Cn1nc(C)c2c(C)onc2c1=O +CC(C)C1(O)CN(C(=O)CCN2Cc3ccccc3C2=O)CC1C +COC(=O)CCC(=O)Nc1ccc(NC(=O)c2ccccc2)cc1 +O=C(Nc1ccc(-n2cncn2)nc1)C1CCOC1 +CCOCCCNc1c2c(c(C#N)c3nc4ccccc4n13)CCC2 +CCN(CC)c1ncc(CN2CCNC(=O)C2C(C)C)s1 +CC(=O)c1ccc(-n2nnc3c(sc4nc(C)ccc43)c2=O)cc1 +Cc1ccc2c(c1)NCCN2CC(=O)c1ccccc1 +Nc1cc(=O)[nH]c(SCC(=O)Nc2c(F)cccc2F)n1 +CC(c1ccccc1F)N(C)C(=O)C1CC(=O)N(C(C)C)C1 +CC1(C)CN(C(=O)CCc2nc(C(C)(C)C)no2)CCO1 +COc1ccccc1-c1nn(C)cc1C(=O)N(C)C +Cn1c(-c2ccc(Br)cc2)cn2c3ccc(N)cc3nc12 +Cc1n[nH]c(-c2cccc(CNC(=O)CNc3ccc(C#N)cc3)c2)n1 +COc1cc2c(cc1OC)CCN(c1nnc(C)c(C)c1C#N)CC2 +CCOC(=O)c1ncn2c(N)c(C(=O)Nc3cccnc3)nnc12 +CCOc1ccc(NC(=O)CNC(=O)Cc2ccon2)cc1 +CCN(CCc1nc2cc(F)ccc2[nH]1)C(=O)c1cnc(C)[nH]c1=O +COc1cc(OC)c(C(=O)Nc2ccc(F)cc2F)cc1OC +C#CCOc1ccc(C(=O)Nc2cc(Cl)ccc2O)cc1 +CC1(C)COCCN1Cc1ccc(-n2ccnc2)cc1 +O=C(c1ccc(F)cc1)N1CCCn2c1nc1ccccc12 +CC(=O)NCCNC(=O)CCC(=O)NC1(C)Cc2ccccc2C1 +CCCN(C)C(=O)Nc1ccc(N2CCOCC2)cc1C(F)(F)F +Cn1c(=O)n(CC(=O)NCCc2cccs2)c2ccccc21 +O=S(=O)(Nc1cnn(Cc2ccc(F)cc2)c1)c1ccc(F)cc1 +COC(=O)CC1CN(Cc2ccccc2-n2cccn2)CCO1 +CCn1c(SC(C)c2nc(N)nc(N(C)C)n2)nnc1C1CC1 +COc1ccnc(NC(=O)c2cc(C)nc3onc(C)c23)c1 +CNC(=O)c1ccc(NC(=O)c2cc(C)cc(C)c2)cc1 +CC(C)CCC(C)NC(=O)NCc1ccccc1-n1ccnc1 +CCN(CC)C(=O)c1ccc(NC(=O)c2cc(C(N)=O)cs2)cc1 +CSc1nsc(NC(=O)c2cccc(OC(F)F)c2)n1 +CCc1ccc(Cl)c(CC)c1NC(=O)N(C)CC(=O)NC(C)C +CC(=O)Nc1cc(C(=O)OC2(C3CCOC3)CC2)ccc1F +CC(C)C(C)N(C(=O)NCCS(=O)(=O)c1ccccc1)C1CC1 +CCN(CC)C(=O)CNc1ccccc1C(F)(F)F +COCC1(NC(=O)c2ccc3nccnc3c2)CCCC1 +CC(C)CCC(=O)NCCc1nc2cccnc2n1-c1ccccc1 +Cc1cccnc1NC(=O)c1cn(C)nc1-c1cccs1 +CCOC(=O)C(C)c1c(C)nn(CCC(C)C)c1C +O=C(COc1ccc(Cl)c(Cl)c1)N1CCC1 +Cc1cc(Br)cc(C)c1NS(=O)(=O)c1cnn(C)c1 +N#Cc1ccsc1NC(=O)CCN1CCN(c2nccs2)CC1 +COc1cccc(F)c1C(C)NC(=O)Nc1cnccc1C +COc1cc(OC)c(-c2cc(C#N)c(=O)n(C)n2)c(OC)c1 +CN(Cc1csc(-c2cccs2)n1)C(=O)CCCc1cn[nH]c1 +O=C(c1ccnc(OC2CCC2)c1)N1CCSc2ccccc21 +COCCOc1ccc(S(=O)(=O)N2CCNC(=O)C2)cc1 +O=C(c1ccncn1)N1CC(OCc2ccncc2)C2OCCCC21 +O=C(COC(=O)c1cc(F)ccc1F)NCc1cccc(Cl)c1 +N#Cc1ncn(CCCc2nnnn2-c2ccccc2)n1 +CCOC(=O)c1cccnc1N(C)C1CCCCC1 +CCN(Cc1ccncc1)C(=O)c1ccc2c(c1)CCN2 +CCOCC(=O)Nc1cccc(NC(=O)c2ccccc2)c1C +Cc1sc(=O)n(CC(=O)Nc2ncc(-c3ccccc3)s2)c1C +CCOC(=O)c1c(NC(=O)C2CCC2)sc(C(=O)NC)c1C +CCC(Oc1cccc(C)c1)C(=O)Nc1ccccc1C(=O)NC +CCOC(=O)Cc1csc(NC(=O)Cc2ccccc2C)n1 +CCc1ccc(C(=O)N2CCCC2c2ccncc2)cc1 +CC(NC(=O)CCSc1ccccn1)c1nc(C2CCCC2)no1 +COc1cc(C#N)ccc1CNCc1ccccn1 +CC(=O)Nc1ccc(SC(C(=O)N(C)C)c2ccccc2)cc1 +Cc1sc2ccccc2c1S(=O)(=O)N1CC(C)OC(C)C1 +Cc1ccc(OC2CCN(S(=O)(=O)c3ccccc3)CC2)cn1 +CCCc1cc(C(=O)NCC(=O)Nc2ccc(C)cc2Cl)[nH]n1 +CC(C)N(Cc1ccc(C#N)cc1)C(=O)c1cn2cccnc2n1 +Cc1nn(Cc2ccc(OC(C)C)cc2)c(=O)c(C#N)c1C +Cc1n[nH]c(SCCOc2ccc(Cl)cc2Cl)n1 +CSc1ccccc1NC(=O)NCc1ccccc1F +Cc1cc(OC(C)c2ccccc2)ccc1NC(=O)C(C)NC(N)=O +O=C(CCn1cnc2ccccc2c1=O)Nc1ccc2cn[nH]c2c1 +CC(C)CCOCCNC(=O)Nc1nccs1 +CC1(C)Cc2c(C#N)c(OCC#N)nc(-c3ccco3)c2CO1 +CCSc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1F +Cc1nc2c(cc1C(=O)N(C)CC(N)=O)c(C)nn2C +Cc1cccc(-n2nnc(C(=O)NCc3ccc(Cl)cc3)c2C)c1 +CSc1cccc(NC(=O)c2cccc(CN3CCOCC3)c2)c1 +COc1cc(OC)cc(C(=O)NCc2ccccn2)c1 +CCC(CCO)NC(=O)NC1CCN(c2ccccc2F)C1=O +COC(=O)c1sccc1NC(=O)COc1ccc(C)cc1OC +Cc1ccccc1-c1c2c([nH]c(=O)c1C#N)CCC2 +Cc1cccc(C(C)C)c1NCc1ccc(=O)[nH]c1 +CC(C)n1cnnc1CN(C)Cc1ccc(-n2ccnc2)cc1 +COC(=O)c1c(C)noc1-c1ccc(Cl)cc1 +COC(=O)CSc1nnc(Cc2ccccc2)o1 +CCc1ccc(OCc2nc(COC)c(C(C)=O)s2)cc1 +CCCS(=O)(=O)N1CCC(NC(=O)c2cccc3[nH]ccc23)CC1 +COCCOCC1NCCc2cc(C)c(F)cc21 +COc1ccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)CO3)cc1 +N#Cc1ccccc1Cn1cccc(C(F)(F)F)c1=O +CC(C)NC(=O)N1CC2OCCN(c3ncc(F)cn3)C2C1 +COc1cc(OC)c(C(=O)Nc2ncccc2C)cc1OC +CCn1c(C)nc2cc(C(=O)CC(C)(C)C)ccc21 +CCN1CCN(C(=O)CCC(=O)c2cccs2)CC1 +CS(=O)(=O)N1CCN(C(=O)COc2ccc3ccccc3c2)CC1 +CCCCNC(=O)C(N)c1ccc(O)c(OC)c1 +COc1ccc(CN2CCN(C(=O)c3cc(C)n(C)n3)CC2)cc1F +N#Cc1c(-c2ccncc2)nc2ccc(C(F)(F)F)cn12 +O=C(c1c(-n2cnnn2)sc2c1CCC2)N1CCCC1 +Cc1ccc(CN2CCc3c(CNC(=O)C4CC4)cncc3C2)s1 +N#Cc1ccc(F)cc1COc1ccc(CO)nc1 +CCNC(=O)CSc1nnc(-c2ccc(Cl)cc2)n1C +CCCCOc1ccc(Nc2nc(=O)[nH]nc2C)cc1 +CC(=O)Nc1cccc(C(=O)OCC(=O)NCc2ccccc2)c1 +Cc1noc(C)c1CN(C)C(=O)c1cccnc1OCC(F)(F)F +Cc1c(F)cccc1S(=O)(=O)N1CC(N(C)C)C1 +CCCNC(=O)CNc1ccccc1CC(=O)N(C)C +N#Cc1ccccc1NC(=O)c1ccn(-c2ccc(F)cc2)n1 +CCNS(=O)(=O)c1ccc(C)c(C(=O)Nc2ccc(C)c(C)c2)c1 +CCOc1ccc(C(=O)OC2CCCC2n2cccn2)cn1 +O=C(NCC1CC1)C1CCCN1C(=O)c1ccco1 +COc1cccc(OCC(=O)NC2CCCc3occc32)c1 +NC(=O)c1cccc(OC(=O)c2cccn2Cc2cccs2)c1 +Cn1c(=O)c2c(nc3oc(C(C)(C)C)cn32)n(C)c1=O +Cc1cc(C)c(C)c(S(=O)(=O)n2cc(Cl)cn2)c1C +COc1c(F)cc(NC(=O)Cn2nnc(-c3ccccc3)n2)cc1F +CC(C)(CO)N(CCO)C(=O)c1ccc(Cl)cc1 +O=C(NCC1CCOC1)c1ccc(Cn2ccccc2=O)o1 +CC(Sc1nncn1C)C(=O)NCc1ccc2c(c1)OCO2 +O=C(OCC(=O)N1CCOCC1)c1cnn(-c2ccccc2Cl)c1 +CC(C)N(C)C(=O)CNc1cc(F)cc(F)c1F +CC(C)CNC(=O)c1c(F)ccc(S(=O)(=O)NC2CC2)c1F +CCCc1noc(CNc2ccccc2SC)n1 +CSc1ccc(OCC(=O)NCc2ccco2)cc1 +C=CCNS(=O)(=O)c1ccc2cc(OCC)ccc2c1 +CCN(CC(=O)OC)C(=O)c1cc(N)c(C)s1 +COC(=O)CCn1c(=O)c2c(nc3oc(C)cn32)n(C)c1=O +Cc1ccccc1OC(=O)c1ccc(C(N)=O)nc1 +COc1cccnc1NC(=O)CCn1c(=O)oc2ccccc21 +N#Cc1ccc(C(=O)NCc2ccc(CN3CCCC3=O)cc2)cc1 +Cn1ncc(C#N)c1NC(=O)c1cccc(Br)c1 +CC(=O)N1CCN(C(=O)c2ccc(Cl)cc2F)CC1 +Cc1ccc(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)c(C)n1 +O=S(=O)(Cc1ccccc1)Nc1cnn(Cc2ccccc2)c1 +Cc1n[nH]c(COc2ccc(C(C)(C)C)cc2)c1CO +Cc1cnn(CCC(=O)N(Cc2cccs2)C2CC2)c1 +CC(C#N)(NC(=O)CNc1cccc2c1OCCO2)C1CC1 +Cc1cccc(NS(=O)(=O)c2cc(C(=O)N(C)C)ccc2C)c1 +CC1CCc2c(C(=O)NCCCO)csc2C1 +CC(C)c1nnc2n1CCN(C(=O)Cn1c(=O)oc3ccccc31)C2 +CC(C)C(NC(=O)Cc1ccccc1)C(=O)Nc1ccc(CC#N)cc1 +COc1ccc(-c2noc(-c3ccccc3NC(C)=O)n2)cc1OC +COC(=O)c1cn(C2CCCCC2OC(C)=O)nn1 +Cc1noc(N)c1-c1cccc(Br)c1 +COc1ccnc(N2CCN(C(=O)c3cc(C(C)=O)cn3C)CC2)n1 +CCCNC(=O)NCc1cccc(OCC(=O)NC)c1 +Cc1c(C(C)NC(=O)Cc2ccc(S(N)(=O)=O)s2)cnn1C +CN(C)C(=O)c1nc2c(n1C)CCN(C(=O)c1ccccn1)C2 +Cc1ccc(NC(=O)c2cc(-c3csc(C)n3)cn2C)cc1 +CC(C)(C)c1ccc2oc(=O)cc(CNC(=O)c3ccco3)c2c1 +CN(CCc1ccccn1)C(=O)CNC(=O)C1CC2CCC1O2 +CN(C)c1ncccc1NC(=O)c1ccc(=O)n(C)n1 +CC(=O)N(C)C1CCN(C(=O)NC(C)CCc2cccn2C)CC1 +CN(C)C(=O)c1ccccc1NCc1cccc(F)c1 +Nc1c[nH]c2onc(-c3ccc(Br)cc3)c12 +O=C(Nc1cccc(S(=O)(=O)C2CCCC2)c1)C1CCOCC1 +Cc1csc(C(C#N)C(=O)CCn2ccccc2=O)n1 +O=C(NCc1ccc(F)cc1)NCC1(O)CCOc2ccccc21 +CC1CCCCC1OCC(=O)NC(C(N)=O)C(C)(C)C +Cn1ncc(C(=O)NCc2ccccc2)c1C(=O)NCc1ccccc1 +CCN(CC)C(=O)CCCNC(=O)N(C)C1CCCC(C)C1 +COCCn1nc(C)cc(-c2csc(NC(C)C)n2)c1=O +FC(F)Oc1ccc2c(c1)CCNC2c1cccnc1 +COc1cccc(C(O)CCCC(=O)N2CCOCC2)c1 +O=C(Cc1cccc(Cl)c1)N1CCC(O)CC1 +CCN(C(=O)COc1cc(C)c(C)nn1)C1CCCCC1 +CC(Nc1ncnc2c1cnn2CCC#N)c1ccc2[nH]c(=O)[nH]c2c1 +Cc1nccc(-c2cccc(NCC(=O)NCc3ccccc3)c2)n1 +CCC1Nc2cc(C)ccc2N(CC(O)CO)C1=O +c1ccc(Cc2noc(-c3scnc3C3CC3)n2)cc1 +Cc1nc2ncnn2c(Sc2ccccc2N)c1C +O=C(NCC(O)c1cccs1)c1ccsc1 +COc1ccc(C(=O)C(C#N)c2ccccn2)c(OC)c1 +Cc1cc(-c2nn3c(CCc4ccccc4)nnc3s2)[nH]n1 +CCOC(=O)C1(C)CCN(C(=O)Nc2ccc3c(c2)COC3)C1 +COC(=O)Cc1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +Cc1cc(C)cc(OCC(=O)NCCCN2CCOCC2)c1 +Cc1nn(C)c(C)c1S(=O)(=O)N(C)Cc1ccoc1 +CNC(=O)NCC(=O)Nc1ccc(OCc2ccccc2F)cc1 +Cc1cccc(-c2nc(CC(=O)Nc3ccn(C)n3)cs2)c1 +CCN(CC)C(=O)CN(C)S(=O)(=O)c1ccccc1F +Fc1ccccc1-n1nc(C2CC2)c2c1CCNC2 +Cn1c(C(=O)NCC(=O)NCCc2ccccc2)cc2sccc21 +O=C(CC1C=CCC1)Nc1ccc(-c2nnc3n2CCCC3)cc1 +CCC(CC)C(=O)Nc1sc2c(c1C(N)=O)CCC(C)C2 +CS(=O)(=O)c1ccc(CN2CCC3(CCCO3)CCC2=O)cc1 +COC(=O)CCNC(=O)c1cc(F)ccc1Br +CCCNC(=O)CN(C)C(=O)CNc1c(C)cccc1Cl +Cn1ccnc1COc1ccc(C(=O)Nn2cnc3ccccc32)cc1 +CS(=O)(=O)c1ccc(F)c(NC(=O)c2cc(F)ccc2F)c1 +CCC(=O)CCc1cc(Br)ccc1OC +CCOC(=O)C(N)CCOc1cc(F)cc(F)c1 +Nc1cn2c(-c3ccc4c(c3)CCC(=O)N4)csc2n1 +NC(=O)N1CCCC1C(=O)N1CCC(Cc2ccc(F)cc2)CC1 +COC(=O)N1CCCC(C(=O)Nc2nc(-c3cccn3C)cs2)C1 +CS(=O)(=O)N1CCCCC1C(=O)NCc1ccccc1 +O=C(NC1CCCCC1)c1cn[nH]c1-c1cccs1 +CC(C)(C)OC(=O)N1CC2C(C1)C2NC(=O)OCc1ccccc1 +O=C(CCN1CCCC1=O)Nc1ccn(-c2ncccc2Cl)n1 +COc1ccc(F)cc1-c1c(N)n[nH]c1CC(C)C +O=C(c1cccnc1)N1CCOC2C(OCc3ccccn3)CCC21 +Cc1cc(C(=O)NCCCC(N)=O)c(C)n1Cc1ccccc1 +CCCCn1nccc1NC(=O)c1cc(Cl)c2c(c1)OCCO2 +O=C(C(NCc1ccccc1F)c1ccccc1)N1CCCC1 +COC(=O)c1sc(NC(=O)Cc2ccccc2OC)nc1C +Cc1cccc(-c2nc3c(N)nc(N)nc3nc2N)c1 +Cc1cc(C(=O)N2CCCC2)ccc1NC(=O)NC(C)(CO)C1CC1 +NC(=O)c1ccc(Cn2nnc(-c3cccc(F)c3)n2)cc1 +O=C(c1cccnc1)N(Cc1ccccc1)Cc1ccccc1 +NC(=O)CSc1nccc(-c2ccc(F)cc2)n1 +Cc1cc(CN2CCN(C(=O)Nc3c(C)cccc3C)CC2)on1 +CC(C)c1noc(OCC(=O)Nc2cccc(C#N)c2)n1 +Cc1nnc(CNC(Cc2ccccc2)C(C)(C)C)o1 +COC(=O)C1=C(C)Nc2nnnn2C1c1cc(OC)ccc1OC +CCOC(=O)C(C)NC(=O)c1c[nH]nc1-c1ccccc1Cl +CC(c1ccco1)N(C)C(=O)COc1ccc(F)cc1F +CCNS(=O)(=O)c1cccc2cccc(Cl)c12 +Nc1nncc(-c2ccncc2)c1C(=O)Nc1ccc(F)cc1 +NC(=O)Cc1csc(NC(=O)Cc2ccc3c(c2)OCCO3)n1 +CC(=O)N1CCCC(Cc2ccc(C(=O)NC(C)C)nn2)C1 +O=C(CSc1ccccc1)NCc1cc2ccccc2o1 +Cc1noc(C)c1CC(C)NC(=O)NC1CCN(c2ccccc2)C1 +CCCCNC(=O)CNS(=O)(=O)c1ccc(N)cc1 +COc1cccc(CNC(=O)CNC(=O)c2cccc(Cl)c2)c1 +O=C(NCCNC(=O)c1nc(-c2ccccc2)no1)c1ccco1 +COc1ccc(Cc2nc3nccc(-c4ccco4)n3n2)cc1 +O=C(c1cccnc1)N1CCN(Cc2ccc(Cl)cc2)CC1 +COc1cc(N2CCOCC2)ncc1Br +CC1CN(C)c2ccccc2CN1C(=O)C1CCOC1 +COc1ccc(S(=O)(=O)Nc2ccc(F)cc2C)cc1 +CC1(C)OC(COC(=O)c2ccccc2)C(C(=O)c2ccoc2)O1 +CSc1ccccc1NC(=O)COc1ccc2ccc(=O)oc2c1 +CS(=O)(=O)NCCC1CCCCN1C(=O)C1CCCC1 +CCCc1cc(C(=O)N2CCCC(OCc3cccnc3)C2)cs1 +O=C(NCCc1cn2ccccc2n1)c1ccc2cc[nH]c2c1 +O=C(c1ccc2cc[nH]c2c1)N1CC(c2nc(-c3ncccn3)no2)C1 +O=S(=O)(c1c(F)cccc1F)N1CCN(CC(O)C2CC2)CC1 +Fc1ccccc1CN(c1ncnc2sccc12)C1CC1 +COc1ccccc1Oc1ncnc(N2CCCC(C)C2)c1N +CCC(CC)C(=O)NC1CCN(C(=O)Cc2ccccc2OC)CC1 +O=C(CNC(=O)c1ccccc1)Nc1nc(C(F)(F)F)cs1 +O=C(Nc1cnc2ccccn2c1=O)NC1CCCCCC1 +COC(=O)CCC(=O)Nc1ccccc1C(=O)NC1CC1 +COCC(=O)N1CCN(Cc2nnnn2-c2ccc(C)cc2)CC1 +O=C(Cc1ccccc1F)N1CCN(CC(=O)N2CCOCC2)CC1 +c1nnc(SCc2nnc(C3CCCO3)o2)n1C1CC1 +CCN(CC)S(=O)(=O)c1ccc(C(C)=O)cc1 +N#Cc1c2c(c(-c3ccccc3)n(Cc3ccco3)c1=O)CCC2 +O=C(CCc1conc1-c1ccc(F)cc1)NCc1ccco1 +CC(C)N(C(=O)c1ccc(C(=O)NCc2ccccc2)cc1)C(C)C +NC(=O)c1cccc(COC(=O)CSc2ccccc2F)c1 +CCCC(=O)NC1CCCN(C(C)C(=O)Nc2ncccn2)C1 +CC(Sc1nnnn1C1CC1)C(=O)Nc1cnn(C(C)(C)C)c1 +CN(C)c1nc(N(C)C)nc(N2CCOCC2)n1 +O=C(COc1cc(F)ccc1F)c1cccs1 +COC(=O)C(O)(c1c(C)[nH]c2ccccc12)C(F)(F)F +CCc1c(C(=O)N(C)CC(=O)NC(C)C)cnn1-c1ccc(C)cc1 +N#Cc1nccn1Cc1coc(-c2ccc(Br)cc2)n1 +Cc1cc(C)c(O)c(-c2cc(C(=O)NCc3ccccc3)n[nH]2)c1 +CC(NC(=O)N1CCCC1)C(=O)N1CCc2ccccc21 +Cc1ccc(C(=O)NCc2c(C)cc(C)[nH]c2=O)cn1 +COCC(=O)Nc1ccccc1NC(=O)c1ccco1 +Cc1cccc(C)c1OCCCn1ccnc1-c1cnccn1 +C#CCNC(=O)c1ccc(COc2ccc(F)cc2)o1 +Cc1cc(CC(C)NC(=O)c2n[nH]c(N)c2-c2ccccc2)[nH]n1 +Cc1cccc(C(=O)Nc2cccc(CS(N)(=O)=O)c2)c1C +CC(C)OCc1nnc2n1CCN(C(=O)c1ccc[nH]1)CC2 +Cc1sc2ncnc(SCCC(=O)NC(C)CO)c2c1C +COc1ccc(OC)c(S(=O)(=O)NCc2ccc(Cl)cc2)c1 +COc1nn(C)c2c1CCCN(C(=O)c1ccc3ccccc3n1)C2 +CN(CCc1cccs1)C(=O)NCc1cc(=O)[nH]c2ccccc12 +Cn1cccc1C1CCCCCN1C(=O)c1cc(-c2ccco2)on1 +CCOC(=O)Nc1ccccc1Cc1nc(-c2ccncc2)no1 +COc1ccc(CNC(=O)c2nonc2C)cc1OC +O=C(CCCc1ccccc1)N1CCc2ccccc21 +COc1ccc(Cl)cc1C(=O)NCCCNS(C)(=O)=O +CC(C)Oc1ccc(C(=O)NCCOc2cccnc2)cn1 +CC(=O)Nc1ccc(OCC(O)Cn2nc(C)nc2C)cc1 +COC(=O)c1ccc(C(=O)N(C)CCc2ccc(F)cc2)s1 +CCOC(=O)c1c(C)nc(N)nc1-c1ccccc1OCC(C)C +O=C(NCCc1ccccc1F)C1CC(=O)N(c2ccccc2)C1 +c1ccc(Cn2nnnc2CN2CCOCC2)cc1 +CN(Cc1ccccc1)c1ccccc1NC(=O)Nc1ccn(C)n1 +CC(NC(=O)c1ccccc1F)c1cccc(S(N)(=O)=O)c1 +O=S(=O)(NCCOc1ccc2c(c1)OCO2)c1cccs1 +CCOC(=O)c1ccc(C)nc1C1CCN(C(=O)OC(C)(C)C)CC1 +COCCC1(O)CCN(C(=O)CCc2cnn(C)c2)CC1C +CN(c1ccccc1-c1ccccc1)S(=O)(=O)c1cn[nH]c1 +Cc1[nH]ncc1S(=O)(=O)N1CCCC1c1ccc[nH]1 +O=C(c1ccco1)N1CC2OCCN(Cc3ccccc3)C2C1 +CC(=O)Nc1ccc(C(=O)Nc2cccnc2-n2cccn2)cc1 +Fc1ccc(-c2nnc(-c3n[nH]c4c3CCC4)o2)cc1Cl +CCc1onc(C)c1NC(=O)NC(C)C(O)c1ccc(F)cc1 +O=C(NCc1cccc(C(F)(F)F)c1)c1ccnc2ncccc12 +O=C(CSc1nc(C2CCCO2)n[nH]1)NCCc1ccccc1 +CCCn1nc(CNc2ccc(Cl)cc2)[nH]c1=O +Cc1nsc(N(C)CCOc2ccccc2F)n1 +COc1coc(C(=O)Nc2ccc(C)cc2)cc1=O +C=CCNC(=O)Nc1ccc(NC(=O)CCc2c(C)n[nH]c2C)cc1 +O=C(NCc1cccnc1)c1ccc2oc(-c3cccc(F)c3)nc2c1 +c1csc(-c2oncc2CSc2nnnn2C2CCOCC2)c1 +CCc1sc(C(=O)Nc2cnn(CC(=O)NC3CC3)c2)cc1C +Cc1ccc(C)c(C(=O)NCc2ccc(Cn3ccccc3=O)cc2)c1 +COc1ccc(C(=O)Nc2ccc(C(C)=O)c(C)c2)nn1 +O=C(NCc1cccnc1)NCc1ccc2c(c1)OCCCO2 +Cc1c(N)cccc1C(=O)Nc1ccc(F)cc1F +Cc1ccc(C(=O)N2CC=C(c3c[nH]c4ncccc34)CC2)c(=O)[nH]1 +CC(Sc1nc(CCC2CCCC2)n[nH]1)C(N)=O +Cc1ccsc1CNC(=O)NCc1cc(C#N)ccc1F +NS(=O)(=O)c1ccc(NC(=O)c2cc3ccccc3o2)c(F)c1 +CNC(=O)c1cn[nH]c1C1(C)CCCN(C(=O)c2coc(C)n2)C1 +COc1ccccc1C(CNC(=O)c1cc(-c2ccco2)on1)OC +N#Cc1ccc(OC(=O)CNC(=O)Cc2cccc(F)c2)c(Cl)c1 +Cc1ccc(C(C(=O)NCc2ccnc3ccccc23)N(C)C)cc1 +CSc1cccc(NC(=O)c2cc(N)ccc2Cl)c1 +CC(NC(=O)CSc1nccn1-c1ccccc1)c1ccccc1 +CCOc1ccc(F)c(C(=O)N2CCC(C)CC2C)c1F +Cc1cccc(NC(=O)Nc2c[nH]nc2-c2ccccn2)c1C +C#Cc1cccc(NCc2cccc(OCC)c2)c1 +CCCNC(=O)Cn1c(-n2nc(C)cc2C)nc(C)c(CC)c1=O +COCCCNC(=O)N1CCC(CC(=O)N2CCOCC2)CC1 +CN(c1ccccc1)S(=O)(=O)OCC(F)(F)F +CCCCC(=O)Nc1ccc(NC(=O)c2cccnc2)c(OC)c1 +CC(C)CNC(=O)C1(NCc2cc(C#N)ccc2F)CCCC1 +O=C(CCc1ccccc1)Nc1nnc(-c2ccco2)s1 +CC(C)(C)C(=O)N1CCC(C(=O)NCc2ccccc2Cl)CC1 +CCOc1ccc(CNC(=O)NC(C)c2c(C)noc2C)cc1C +Clc1ccc2nc(CSc3nnnn3Cc3ccco3)cn2c1 +Cc1nc(COc2ccc(C(=O)NC3CCc4ccccc43)cc2)no1 +COC(=O)Cc1csc(NC(=O)C2CCCCCC2)n1 +Cc1cc(C)nc(NC(=O)c2cc(Br)c[nH]2)n1 +Cc1ccc(C(C)NC(=O)N2CCC3(CC2)OCCO3)cc1 +COc1ccc(C(=O)CSc2nc(-c3ccncc3)n[nH]2)cc1C +CC(C)N(C(=O)COC(=O)c1n[nH]c(=O)c2ccccc12)C(C)C +CC(C)c1cc(C(=O)N(C)c2cc(Cl)ccc2C#N)on1 +Cc1ccc(CNC(=O)C(c2ccccc2)n2cnnn2)cc1 +COCC(=O)N1CCCC1c1cccc(Cc2ccccc2Cl)n1 +CC(=O)Nc1cc(C(=O)OCC2COc3ccccc3O2)ccc1F +O=C(CCc1cccnc1)NCc1ccc(OC(F)F)cc1 +Cc1nc(CNC(=O)CC(C)CC(C)C)c(C)s1 +CC1(C)CCC(CNC(=O)C2CCC(=O)N2)CC1 +Cc1nn(Cc2n[nH]c(=O)n2CC2CCCCC2)c(C)c1C +COc1cc(OC)c(OC)cc1CC1C(=O)N(C)c2ccccc21 +COC(=O)C1(N(C)C(=O)CCC2CCC2)CCCCC1 +CNC(=O)CCC(O)c1ccc(Br)cc1 +CCc1c(C2CCN(C(=O)c3cc(C)on3)CC2)noc1N +Cc1cc(-c2nnc3sc(-c4cnccn4)nn23)n(C)n1 +CNC(=O)C1CCCCN1S(=O)(=O)c1ccc(SC)cc1 +OC(CN1CCOCC12CCCC2)C(F)(F)F +CN(C(=O)OC(C)(C)C)C1CCN(C(=O)c2cnccn2)CC1 +CCC(C)OC(=O)CCn1nnc2ccccc2c1=O +CCOC(=O)c1ccc(CNC(=O)C(C)(C)C#N)cc1 +CC(C)S(=O)(=O)NCC(Cc1cccc(F)c1)N1CCCC1=O +CCN(C(C)C)S(=O)(=O)c1ccc(O)c(N)c1 +COc1ccc(CC2CCN(C(=O)c3ccnc(C)n3)CC2)cc1 +NC(=O)c1ccc(OC(=O)Cc2coc3ccc4ccccc4c23)cc1 +O=C(NCc1ccncc1)Nc1cccc(F)c1F +Cc1nnc(C(C)n2nc(-c3cccs3)oc2=O)o1 +Cc1ccc2cccc(OCC(=O)N(C)C3CCCCC3)c2n1 +COC(=O)N1CCCC(NC(=O)NC2CCCC2)C1 +CCCC(C)NC(=O)Nc1ccccc1COC +O=C(NCc1cc(F)cc(F)c1)c1cn(Cc2ccc(F)cc2)nn1 +Cc1cnc2c(c1)nc(C1CC1)n2Cc1cccc(C#N)c1 +O=C(CN1CCN(c2ccc(O)cc2)CC1)N1CCCCC1 +COc1ccc(CN(C)C(=O)c2ccn(C)c(=O)c2)c(OC)c1OC +CCCC(C)N(C)C(=O)c1cc(F)c(NC)c(F)c1 +CC(c1cc2ccccc2o1)N(C)C(=O)c1ccc(C#N)cc1 +CCCCCNC(=O)c1ccnc(-n2cncn2)c1 +CCc1cccc(NC(=O)CSc2nnc(C(F)(F)F)n2N)c1 +COc1cccc2cc(C(=O)N3CCOCC3CC(C)C)oc12 +Cc1cc(CC(C)NC(=O)c2cc(Cn3nc(C)cc3C)[nH]n2)[nH]n1 +CC(C)(Oc1ccc2c(c1)CCCC2=O)C(=O)NC1CCCNC1=O +NC(=O)c1coc(-c2csc(-c3ccccc3)n2)c1 +COC(=O)Nc1ccc(OC(C)C(=O)Nc2cccc(F)c2)cc1 +Cc1cc2c(=O)n(CC(=O)NC3CCCCC3)cnc2s1 +Cc1cccc(C)c1OCCNC(=O)C(C)n1cncn1 +COc1ccc(Cl)c(-c2nc3c4c(ncn3n2)CCC4)c1 +O=C(c1coc(COc2ccc3c(c2)OCO3)n1)N1CCCC1 +O=C(Nc1ccnc2ccnn12)c1cccc(OCC(F)F)n1 +COC(=O)CSc1nnc(N)n1CC(=O)NC1CCCCC1 +CCc1ccc(OCC(=O)NCc2ccoc2)cc1 +Cc1csc(C(N)c2ccc(F)c(Cl)c2F)n1 +C=CCc1ccc(OCC(=O)NC2CCC(O)CC2)c(OC)c1 +COc1c(C(O)C(=O)NC2CC2)cc(C)cc1C(C)(C)C +COC(=O)c1sccc1NC(=O)c1cccc(OC)c1OC +O=C(CNc1ccccc1C(=O)NCC1CCCO1)NC1CCCC1 +C#CCN(C1CCCCC1)S(=O)(=O)c1c(C)noc1C +COc1ccc(-n2c(C)nnc2SCC(=O)N2CCC2)cc1 +Cc1cc2ccccc2n1CC(=O)N1CCN(c2cnccn2)CC1 +CCN(CC)C(=O)CCc1c(C)nc2ncnn2c1C +COc1ccc(CN(C)C(=O)c2ccc(SC)nc2)c(OC)c1 +Cc1nc(-n2cccc2)sc1C(=O)N1CCc2ncncc2C1 +Cc1ccc2cccc(OCc3nnc(SCC(N)=O)n3C)c2n1 +CC(=O)Nc1ccc(N2CC(C(=O)N3CCCC3)CC2=O)cc1 +COc1ccc(OCCS(=O)(=O)N(C)c2cccc(C#N)c2)cc1 +CC(C)CC(=O)NC(C#N)c1ccccc1Cl +CSc1nc(C)nc(C)c1C(=O)Nc1nc(-c2ccco2)cs1 +CC(NC(=O)Nc1cccc(N)c1)c1nncn1C +O=C(Nc1ccnc2ccnn12)C1(c2ccccc2)CCC1 +Cc1cn2c(CN(C)C(=O)C3CCCc4[nH]ncc43)c(C)nc2s1 +CC(C)CCNC(=O)NCc1cccc(NC(=O)C2CC2)c1 +Cn1c(=O)n(CCC(=O)NCC2CCCO2)c2ccccc21 +CCOC(=O)C(NC(C)CC)c1c(F)cccc1F +N#Cc1cccc(C(=O)N2CCN(c3nc4ncccc4o3)CC2)c1 +C#CCCOC(=O)Cn1cnc2c(C)cccc2c1=O +CC(C)CN(CC(N)=O)S(=O)(=O)c1ccc(F)cc1 +CNc1cc(C2CN(CC(=O)N(C)C)CCO2)nc(C)n1 +C=C(C)CN1CCN(C(=O)Cc2ccccc2Cl)CC1 +Cc1ccc(C(=O)NCCc2cn3ccccc3n2)c(C)c1 +C=C(C)COc1ccc(-c2nc3n(c2CO)CCS3)cc1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Nc1ccccc1Cl +Nc1oc2c(c1C(=O)c1cscn1)CCc1ccccc1-2 +Nc1ccc(Cl)cc1C(=O)Nc1cccc(F)c1 +COc1ccc(NC(=O)N(C)C(C)CC#N)cc1OC +CCC1CN(Cc2cc(=O)n(C)c(=O)n2C)CCO1 +O=C(Nc1cc[nH]n1)c1ccc2ccccc2c1O +O=S(=O)(Nc1ccc(F)c(F)c1)c1cccs1 +Cc1cc(SC(C)C(=O)c2ccccc2)n(C)n1 +Cc1noc(C2CCCN2C(=O)C2CCC(=O)N2)n1 +COc1ccccc1-c1cc(NC(=O)C2CCCO2)[nH]n1 +CCn1nc(C)c(CCNC(=O)NCc2cccc(OC)c2)c1C +COc1cccc(OCc2c(C#N)nnn2C(C)C)c1 +Cc1ccc(S(=O)(=O)Cc2ccc(C(=O)N(C)C)cc2)cc1 +N#Cc1ccc(NCCNC(=O)C2CC(=O)N(C3CC3)C2)nc1 +Cc1c(-c2ccccc2)nc(SCc2nnc(C(C)C)o2)[nH]c1=O +Cc1cccc(OC(=O)CN2C(=O)CSc3ccccc32)c1C +Cc1cc(C(C)O)c2c(c1)C(NC(=O)C(C)C)CCO2 +CCC(=O)NCc1cc(=O)oc2ccc(C(C)C)cc12 +CC(=O)c1ccc(NC(=O)COC(=O)c2ccccc2)cc1 +COCCNC(=O)CSc1ccc(-c2ccncc2)nn1 +C=CCNC(=O)N1CCC(c2cccs2)CC1 +OCCN(Cc1cn2cccnc2n1)c1ccc(Br)cc1 +Cn1c(C(=O)NCC(=O)NCCc2ccc(F)cc2)cc2occc21 +CC(=O)NCCOc1nc(N(C)C)nc(N(C)C)n1 +CCc1nncn1C1CCN(C(=O)c2cc(-c3cccs3)n[nH]2)C1 +COC(=O)C1CCN(c2ncnc(-n3nc(C)cc3C)c2N)CC1 +O=C(Nc1cccc2cccnc12)c1cccc(OC(F)F)c1 +Cc1nc(=O)c(-c2ccccc2)c(C)n1CCCN1CCOCC1 +C=CCNC(=O)CCCNC(=O)c1ccsc1 +c1ccc(Cn2c(SCCc3ccccn3)nnc2C2CC2)cc1 +CC1CCN(C(=O)c2cccc(OCc3cscn3)c2)C(C)C1 +O=C(NCCCOC1CCOC1)Nc1ccc2c(c1)COC2 +O=C(CCc1cccs1)NCc1ccc(Cn2cccn2)cc1 +CCn1nnc2cc(C(=O)OCCCNC(C)=O)ccc21 +CC(=O)NCCNC(=O)Nc1cc(C(F)(F)F)ccc1F +Cc1ccc(CCc2nc(C3CCOC3)no2)cc1 +Cc1ccc2c(c1)nc(CN1CCOCC1)n2CCC#N +CC1CCc2sc(C(=O)NC(C)CO)cc2C1 +N#Cc1cnc2nc(-c3ccc(Cl)cc3)nn2c1N +COCCN(CC(C)C)S(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +CCc1ccc(C(NC(=O)CNC(C)=O)C(C)C)cc1 +COc1ccc2sc(NCCN3CCOCC3)nc2c1 +O=C1CCCc2c1nc(-c1ccccc1Cl)n2O +CC(C)(C)c1ccc(C(=O)NCCCNC(=O)c2ccco2)cc1 +COc1ccc(-c2onc(C)c2C(=O)NCCc2cccs2)cc1 +CCOC(=O)c1cnn(-c2ncccn2)c1C(F)(F)F +O=C1CCCN1Cc1nnc2n1CCN(C(=O)c1ccncc1)C2 +O=C(Nc1ccccc1SC(F)F)N1CCCC1 +CCc1ncc(NC(=O)Nc2cc(-c3ncco3)ccc2C)cn1 +CCc1[nH]nc(NC(=O)c2cc3ccccc3[nH]2)c1C +Cn1ncc(C(=O)Nc2cc(-n3cccc3)ccc2F)c1-n1cccc1 +CC(C)(C)NC(=O)c1nnc2ccc3ccccc3n12 +CCOCC(=O)N1CCCC(c2nnc(Cn3ccnc3)n2C)C1 +CC(C)n1ncc2c1N=C(O)CC2c1cccc2nccnc12 +Cc1cccc(C(=O)Nc2ccc(OCC(=O)N(C)C)c(Cl)c2)n1 +COCCC(=O)NCc1ccnc(OC2CCC(C)CC2)c1 +OC(CSc1nnnn1Cc1cccs1)c1cccc(F)c1 +Cc1cc(O)cc(C)c1CNc1ccccc1C#N +CNC(=O)c1ccc(NC(=O)c2cccc(Cl)c2)cc1Cl +Cc1ccc(CN2CCC(N3CCOCC3)C2Cc2cnn(C)c2)o1 +Cc1cc(-c2nnc(NC(=O)C3CCC(=O)N3)o2)c(C)o1 +CCN1CC(C(=O)Nc2cc(Cl)ccc2-n2cncn2)CC1=O +COc1ccccc1C=CCN1CC(C)OC(C)C1 +COCCN(C)C(=O)NC(C)c1oc2ccc(OC)cc2c1C +COc1ncccc1-c1cnoc1-c1ccsc1 +CC(=O)c1ccc(N2CCN(C(=O)c3ccoc3C)CC2)cc1 +N#CCCC(C#N)COc1ccc(NC(=O)c2ccco2)cc1 +COc1cc(-c2noc(CCC(N)=O)n2)cc(Cl)c1OC +CC(=O)NC1CCCN(C(=O)NCCOc2ccc3c(c2)OCO3)C1 +CCOC(=O)c1cnc(Nc2nc(C)c3cccc(C)c3n2)nc1C +Cc1nnc(SCc2ccccc2OC(C)C)n1CC(=O)N(C)C +CC(C)NC(C)(C(N)=O)c1cc(F)c(Cl)cc1Cl +CC(C)CN(C(=O)NC1CCC2(CC1)OCCO2)C1CC1 +CC(=O)c1cccc(NCC(=O)Nc2cc(C)nn2C(C)(C)C)c1 +Cc1cc(C(=O)Nc2ccc(OCC3CCOCC3)cc2)c(C)o1 +O=C(NCCCc1cccc(F)c1)Nc1nnc(C(F)(F)F)s1 +Cc1ccccc1CNC(=O)Cn1ncc2c(Cl)cccc21 +O=C(NCCCNC1=NS(=O)(=O)c2ccccc21)c1ccco1 +COCc1ccccc1NC(=O)c1cncn1-c1ccc(F)cc1 +COc1ccc(CC(=O)NC2CN(c3ccccc3)C2=O)cc1 +O=C(c1ccccn1)N1CCOC2C(OCc3cccnc3)CCC21 +CCC(C)NC(=O)CSc1cc(=O)n(C)c2cc(Cl)ccc12 +Cc1ccc(CNC(=O)c2ccc3c(c2)NC(=O)CO3)c(C)c1 +O=c1[nH]nc(CSc2n[nH]c(=O)n2CC2CCCO2)[nH]1 +Cc1nc(-c2ccsc2)sc1C(=O)N1CCN(C(C)C)CC1 +O=c1cc(Sc2ccccn2)c2ccccc2o1 +O=C(CNC(=O)c1ccco1)Nc1ccc(F)cc1 +Cn1cc(CNc2nnc(-c3cccs3)o2)cn1 +CCOc1c(Cl)cc(C(=O)N(C)Cc2nc(C)n[nH]2)cc1OC +O=C(NCCn1ccc2ccccc21)c1cnn2c1OCCC2 +CCOC(=O)C1CCCOc2ccc(C(C)C)cc21 +Cc1ccsc1C(=O)Nc1ccc2c(c1)oc(=O)n2C(C)C +C#CCNC(=O)C(C)Oc1ccccc1C(O)CC +CCCC1=C(C(=O)OCC)C(c2ccc(F)cc2)n2ncnc2N1 +CSc1ccc(NC(=O)N(C)C(C)CC#N)cc1Cl +COc1c(F)cccc1NCc1ccc(O)c(F)c1 +Cc1cc(C)cc(C(=O)NCC(=O)N(C)Cc2ccccc2C)c1 +Cc1c(N)cccc1-c1nnc(N2CCCCC2)o1 +Cc1nnc(-c2cc3ccccc3n2CC(N)=O)o1 +O=C(Nn1cnc2c(cnn2-c2ccc(F)cc2)c1=O)c1ccccc1 +CCOC(=O)N1CCN(c2ncccc2C#N)CC1 +Cc1cc(SCc2cccc(C#N)c2)nc(C)n1 +Cc1csc(N2CCCC(OCc3cccnc3)C2)n1 +CNC(C)C1NCCc2ccc(OC)c(Br)c21 +CC(C)NC(=O)Nc1ccc(NC(=O)CCOC(C)C)cc1 +COc1ccc(NC(=O)Nc2ccc(Cl)c(N)c2)cc1 +COC(=O)NCCCC(=O)N(C)C1CCc2ccccc2C1 +NC(=O)c1ccc(C#CCNC(=O)c2ccc(C(F)(F)F)cc2)cc1 +CCCCNC(=O)c1ccc(-c2cc(N3CCCC3)ncn2)cc1 +Nc1ccc(Cn2c(CCO)nc3ccccc32)cn1 +CN(C)S(=O)(=O)Nc1ccc2c(c1)Cc1ccccc1-2 +COc1ccc(OCCC(=O)N2CCCC2Cn2cccn2)cc1 +Cn1cccc1C(=O)N1CCC2(CC1)CCN2S(C)(=O)=O +COCCCN1CC2=C(C1=O)C(c1ccc(SC)cc1)NC(=O)N2 +COCCNc1nc2ccccc2c(=O)n1Cc1ccco1 +Cc1cc(C(=O)NCC(O)(c2ccco2)C2CC2)no1 +CNc1nc(-c2cccn(CCOC)c2=O)cs1 +CCC(C)n1cc(O)c(=O)cc1CN(C)CCO +CS(=O)(=O)c1cccc(C(=O)NCc2ccc3c(c2)OCO3)c1 +Cn1cc(CCC(=O)NCCc2nc3ccccc3n2C)cn1 +O=C(NC1CCC1)C1CC2CCN(Cc3cccs3)CC2O1 +O=C(CNS(=O)(=O)c1ccccc1)NCC(=O)N1CCCCC1 +COCCC(=O)NC1CC(=O)N(CCc2cccc(Cl)c2)C1 +O=C(Nc1cccc2[nH]nnc12)N1CCN(C2CCOCC2)CC1 +Cc1ccnc(NC(=O)c2ccc(CNC(=O)OC(C)(C)C)cc2)c1 +Cc1ccc2c(c1)N(C(=O)NCC1CCCO1)CCO2 +Cc1ccc2nc(CN3Cc4ccccc4CC3C(N)=O)[nH]c2c1C +CC(C)(C)OC(=O)N1CCCC(CCOc2ncc(Cl)cn2)C1 +CCNS(=O)(=O)c1ccc(C(=O)Nc2cc(C)cc(C)c2)cc1 +COc1cc(C#N)ccc1Oc1ccc(NC(=O)Cc2ccc[nH]2)cc1 +CC(Cn1cncn1)NC(=O)CC(c1ccccc1)c1ccccc1 +CCc1c(C(=O)Nc2ccccc2C(C)=O)cnn1Cc1ccccc1 +CCCC(=O)NCCNc1nc(C)cc(N2CCCCC2)n1 +CS(=O)(=O)c1ccccc1NC(=O)c1ccc(F)c(F)c1 +N#Cc1ccccc1OCc1nnnn1-c1ccc(OC(F)F)cc1 +N#CCCN(CCC#N)C(=O)c1ccc(NC(=O)c2ccccc2)cc1 +CC(=O)c1ccc(OCCCC(=O)Nc2nc(C)cs2)cc1 +CC(C)n1nc(-c2ccccc2)cc1NC(=O)NCc1ccnn1C +COc1ccc(Cl)cc1CNC(=O)Cn1cnc(C#N)n1 +CCC(C)(C)c1nnc(NC(=O)Cc2ccccc2OC)s1 +COC(=O)c1sc(NC(=O)c2occc2C)nc1C1CC1 +Cc1nc(C)c(CC(=O)N2CC(c3ccncc3)C2)c(=O)[nH]1 +O=C(NCc1coc(-c2ccccc2)n1)N1CCOCC1C1CC1 +CCC1CN(S(=O)(=O)c2ccc(N3CCCC3=O)cc2)CCO1 +NC(=O)C1CCN(C(=O)c2ccc(Br)cn2)CC1 +CCc1nc(CC(=O)NCc2ccc(C#N)cc2)cs1 +CC1CCC(NC(=O)c2ccc3c(c2)OCO3)CC1 +COCC(C)NC(=O)NC(C)c1cc(C)sc1C +COc1cccc(C(O)c2cc(OC)c(OC)c(OC)c2)c1 +O=C(NCc1ccncc1)c1ccc(-n2ccnn2)cc1 +OCc1nc(C2CCOC2)nn1C1Cc2ccccc2C1 +O=C(NCc1nncn1C1CC1)c1cc(=O)[nH]c2ccccc12 +CCCn1ncc(-c2ccc(F)cc2)c(CO)c1=O +CNC(=O)CCCN(C)S(=O)(=O)c1c(F)cccc1Cl +COc1ccnc(N2CCN(CC(C)O)C(C)C2)n1 +CCc1cc(NCC(O)COC)nc(-c2ccncc2)n1 +COc1cc(C(=O)Nc2cnc3n2CCCC3)c2ccccc2n1 +CCn1ncc(C(O)C(Cl)(Cl)Cl)c1C +COC(CNC(=O)c1cc(-c2ccccc2)on1)c1cccc(F)c1 +Cc1cc(C)n(-c2cc(Oc3ccccc3)ncn2)n1 +Cc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)c(-n2cnnn2)c1C +CC(C)(C)c1csc(CNC(=O)c2ccc(-n3ccnn3)cc2)n1 +CCOC(=O)c1ccoc1Cn1cnc2c(cnn2C)c1=O +COC(CNC(=O)CC(C)(C)C)c1cccc(F)c1 +O=C(NC1CCN(C(=O)NC2CC2)CC1)c1ccsc1 +CSc1nc(-c2cccnc2)cc(-c2ccco2)c1C#N +Nc1cccc(NC(=O)Oc2ccc(Cl)cc2)c1 +Cc1c(C(=O)Nc2ccccc2NS(C)(=O)=O)oc2ccccc12 +Cc1ccc(CN(C)C(=O)c2cc(=O)[nH]c3ccccc23)o1 +CCCCOc1ccccc1NC(=O)N(C)Cc1ccncc1 +COC(=O)C1CN(CC(C)C)CCN1C(=O)c1ccccc1 +CCC(=O)N1CC(c2nc(-c3ccncc3)no2)C1 +COC(=O)CCC(=O)N1CCCC(CCc2c(F)cccc2F)C1 +NC(=O)c1ccc(NC(=O)c2ccc(Cl)cc2Cl)cc1 +Cc1nnc(-c2ccccc2CCc2c(C)n[nH]c2C)o1 +O=C(NCCc1cc(F)cc2c1OCOC2)NCc1ccc(F)cc1 +CC(C)Oc1cccc(F)c1-c1ccc(=NS(C)(=O)=O)[nH]c1 +Cc1n[nH]cc1NC(=O)Cc1ccc(CC(C)C)cc1 +O=C(OCCNc1ncccn1)C1CCCN(C(=O)C2CC2)C1 +O=C(NCc1cscn1)NCC1(c2ccc(F)cc2F)CC1 +Cn1ccc(C(=O)Oc2cccc(C(=O)Nc3ccccc3)c2)cc1=O +COc1ccc(NC(=O)COC(C)C)cc1NC(=O)c1ccccc1 +CN(Cc1ccc(F)cc1)C(=O)c1ccc2c(c1)NC(=O)CS2 +COC(=O)c1cccc(OCC(=O)NC(C)c2ccc(F)cc2)c1 +CS(=O)(=O)N(CC(=O)Nc1cccc(F)c1)c1ccccc1F +COc1ccccc1CC1NCCc2ccc(O)c(F)c21 +Cc1cc(C)n(CC2CCN(C(=O)C3CCC(=O)N3)CC2)n1 +COc1ncccc1C(=O)NCC#Cc1ccc(C(N)=O)cc1 +CC(C)(C)c1nnnn1CC(=O)Nc1ccc(F)cc1 +CCN(Cc1ccoc1)C(=O)c1cc(N2CCCC2=O)ccc1Cl +Cn1c(SC2CCCCNC2=O)nnc1-c1ccccc1 +COc1ncccc1CNC(=O)CCc1nc(C(C)(C)C)no1 +Cc1nc(C(=O)N(C)C)ccc1C(=O)NC(C)C1CCCCC1 +Cn1ncc(Cl)c1C(=O)NCc1ccccc1Cl +CCOCc1cccc(NC(=O)c2cnc3ccc(C)cn23)c1 +CCN(CC)S(=O)(=O)N1CCC(C(=O)N2CCC(C)CC2)CC1 +O=C1c2ccccc2NC(c2ccccc2)N1CC1CCCO1 +O=C(NC1CCCN(c2cccnc2)C1=O)N1CCCCCC1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)C(C)Oc1ccccc1 +C=C(C)CN(CC)C(=O)NCc1cccc(C(N)=O)c1 +COc1cc(OC)cc(C(=O)Nc2cc(F)ccc2C)c1 +CC(NC(=O)NCC(O)c1ccco1)c1cccc2ccccc12 +CCC(C)N(CC)S(=O)(=O)c1ccc(C(C)=O)cc1 +Cc1cc(F)ccc1-n1cnc2ccccc2c1=O +Cc1nn(-c2ccccc2)c(C)c1C(=O)OCCN1CCOC1=O +CC(C)COc1ncccc1C(=O)NC1CCCC1 +CC1CCCC(NC(=O)NCCCCN2CCOCC2)C1C +O=C(Cn1ccnc1)NC1CCN(C(=O)C2CCCCC2)CC1 +N#Cc1ccccc1NC(=O)CCn1nnn(-c2cccs2)c1=O +Cc1c(Br)c(C(=O)NCCN2CCOCC2)nn1C +Cc1noc(C)c1S(=O)(=O)N(C)C(C#N)c1ccco1 +Cc1cc(NC(=O)CSc2nnc(-c3ccccc3F)o2)no1 +CN(C)S(=O)(=O)c1ccc2[nH]c(COC(=O)c3ccco3)nc2c1 +Cc1c(N)cncc1C(=O)Nc1cccc(Cl)c1Cl +CNC(=O)c1cc(Cl)ccc1NCC(=O)Nc1cc(C)nn1C +Cc1nncn1CCNC(=O)c1cnc(Cc2ccccc2)s1 +Cc1nnc(SCCNc2nc3c(s2)c(C)nn3C)s1 +Cc1noc(C2CCCN(C(=O)Nc3ccc4c(c3)COC4)C2)n1 +COc1cccc(NCCc2n[nH]c(-c3ccc(N)cc3)n2)c1 +COc1ccc(C(=O)Nc2c[nH]nc2C)cc1OC +CSc1ccc(NC(=O)NCc2cnn(C)c2)cc1 +COC(C)CCOC(=O)c1ccc(-n2ccnn2)cc1 +Cc1cc(NC(=O)c2cc(S(=O)(=O)N(C)C)oc2C)ccc1F +Cc1n[nH]c(=NC(=O)c2cccc(NC(=O)NC(C)C)c2)n1C +Cc1cc(-c2nc3c4ccccc4ncn3n2)n[nH]1 +Cc1ccc(NC(=O)c2cccs2)cc1-n1cnnn1 +NC(=O)C1CCCCN1C(=O)CN1CCN(c2nccs2)CC1 +CCOC(=O)C1(NC(=O)c2cccc(F)c2)CCCC1 +CN(C)C(=O)CNC(=O)C1CCC(=O)N(C)C1c1ccccc1F +COc1cc(C)sc1C(=O)OCCNc1ncccn1 +Cc1nn(C(CC#N)c2ccccc2)c(C)c1Br +CC(=O)c1ccc(NC(=O)CC(C#N)c2ccccc2C)cc1 +Cc1cnc(NCCSc2nccn2C)nc1-c1ncnn1C +CCOc1ccc(Cl)c(C(=O)Nc2ccc(NC(=O)CC)cc2)n1 +CC(C)c1nnc(CNC(=O)C2OCCc3ccccc32)n1C +CCNC(=O)c1cccc(CNC(=O)NC(CC)CO)c1 +COc1cc(CNCCc2ccccn2)cc(OC)c1 +CC(OC(=O)C1COc2ccccc21)c1ccc2c(c1)OCCO2 +O=C(c1n[nH]c(=O)c2ccccc12)N1CCC(c2ccccc2)C(O)C1 +Cc1nc(N2CCCC2)cc(N2CCN(S(C)(=O)=O)CC2)n1 +Cc1ccc2c(c1)N(CC(=O)NCc1ccc(Cl)cc1)C(=O)CO2 +CN(C)Cc1cc(=O)n2c(n1)CN(C(=O)c1cnccn1)CCC2 +CCn1c(C)cc(C(=O)OC(C)C(=O)Nc2ncccn2)c1C +COc1cccc(CC(=O)NCCS(N)(=O)=O)c1 +Cc1cnc2c(S(=O)(=O)N3CCCCC3C(N)=O)cccc2c1 +COCCCC(=O)Nc1nc(C)c(Cc2ccc3c(c2)OCO3)s1 +COCCNC(=O)c1ccc(N(C)S(C)(=O)=O)cc1Cl +O=C1C(Sc2cn[nH]n2)CCN1c1ccc(F)c(Cl)c1 +CN(C)c1cccc(C(=O)N2CC3CC(C2)c2cccc(=O)n2C3)c1 +CC(C)CC1COCCN1C(=O)Nc1ccc(NC(=O)C(C)C)cc1 +CC(=O)Nc1cc(C(=O)Nc2ccc(-n3cncn3)cc2)ccc1C +O=C(CCc1nc2ccccc2[nH]1)N(Cc1ccc(O)cc1)CC1CC1 +CCN(Cc1ccc2c(c1)OCO2)S(=O)(=O)CC +O=C(Cc1ccc(O)cc1)Nc1ccccc1C(=O)NC1CC1 +Cc1ccc(Cl)c(OCc2nnc(C3CC3)o2)c1 +O=C(NCc1ccco1)c1cc2cc(-c3ccccc3)ccn2n1 +Cc1ccccc1C(=O)CNC(=O)c1ccccc1N +Cc1cc(NC(=O)C(C)Oc2ccc(Cl)cc2)no1 +CC1Cc2ccccc2N1Cc1ccc(N)c(F)c1 +CCC(=O)c1ccc(S(=O)(=O)Cc2ccccc2)cc1 +Cc1ccc(S(N)(=O)=O)cc1NC1CCCC(C)C1 +COc1ccc(F)cc1NC(=O)NC1CCCn2nc(C(C)C)nc21 +Cc1n[nH]c(SCC(=O)NC2C(C)CCCC2C)n1 +Cc1ccc(CC(=O)Nc2cnn(-c3ccccc3F)c2)cc1 +Cc1ccccc1Cc1nc(Cn2cnc(C#N)c2C#N)no1 +Cc1cc(C)c(Cn2c(=O)oc3cccnc32)c(C)c1 +CC(C)Nc1ncnc(NCCc2ccccc2)c1N +N#CC1(NS(=O)(=O)c2ccc(Cl)cc2)CCCCC1 +CC1CC(C)CN(C(=O)Nc2ccnn2C(C)C)C1 +COc1ccccc1NC(=O)CSc1nc2c(=O)[nH]cnc2n1C +Cc1ccnn1-c1cccc(NC(=O)N2CCCC(O)C2)c1 +COC(=O)CSc1nnc2c3c4c(sc3nc(C)n12)CCCC4 +CCOCC(=O)Nc1ccc2nc(C(C)C)sc2c1 +COCCNC(=O)CCCN1C(=O)COc2ccc(C)cc21 +CCC(C(=O)Nc1ncn(CC(=O)NC)n1)c1ccc(F)cc1 +CNc1ccccc1C(=O)OC(C)C(=O)NC1CCCC1 +CCCN(CC(F)(F)F)C(=O)c1ccccc1O +CC1CCN(C(=O)Cn2nnc3ccccc32)c2ccccc2S1 +O=C(Cc1ccc(F)c(F)c1)NCc1ccnc(-n2ccnc2)c1 +CC(C)C(=O)N(C)c1ccccc1S(C)(=O)=O +CCCC(=O)N1CCC(C(=O)NC2CCCCc3ccccc32)CC1 +CSc1ccc(C(=O)N(Cc2ccccn2)CC(C)C)cc1 +Cc1noc(C)c1C(C)NC(=O)Nc1cccc(NC(=O)C2CC2)c1 +CC(=O)NCCCNC(=O)c1cccn(Cc2cccc(C)c2)c1=O +Cc1cc(C)n(Cc2nc(C3CCOC3)no2)c(=O)n1 +O=C(c1ccco1)N1CCCC(c2nc(-c3ccc(F)cc3)no2)C1 +CCc1cc2c(=O)n(CC(O)c3cc(F)ccc3F)cnc2s1 +Cc1ccc(CNC(=O)Nc2ccc(C(=O)NC(C)C)cc2)cc1F +COc1cc(C2NCCc3c(N)cc(F)cc32)ccc1O +Nc1ccc2c(c1)oc(=O)n2CCOc1ccccc1 +CC(=O)NCC(=O)N1CCC(O)C1Cc1cccnc1 +CN(Cc1cnn(C)c1)C(=O)CN1CCN(c2nccs2)CC1 +Cc1cc(C)n(-c2ccc(CNC(=O)N(C)CC3CCCO3)cn2)n1 +O=C(Nc1c2c(nn1-c1ccccc1)CCC2)C1CCCO1 +Cc1ccccc1OCCCC(=O)Nc1nnc(C(C)C)s1 +CCN1CC2(CCC1=O)CCN(C(=O)c1ccc3occc3c1)CC2 +COc1ccc(-c2nc3cc(N)ccc3o2)cc1F +COc1ccc(NC(=O)CS(=O)(=O)c2c[nH]c3ccccc23)cc1 +Cn1cc(NC(=O)c2ccc(-n3ccnn3)cc2)c(=O)n(C)c1=O +Fc1ccc(CN2CCCC(c3cnccn3)C2)cc1F +O=S1(=O)N=C(Nc2ccc(Cl)cc2Cl)c2ccccc21 +CCc1cc(C(=O)Nc2ccc(N3CCCCC3)cc2C(N)=O)[nH]n1 +COc1ccc(-c2nc(-c3ccc(C(=O)NC4CC4)s3)no2)cc1 +Cn1cc(CCCSc2ncnc3ccccc23)cn1 +C=CCNC(=O)c1ccc(C)c(S(=O)(=O)Nc2ccc(C)cc2)c1 +CCOc1cccc(C(=O)Nc2ccc(-c3nc(C)cc(=O)[nH]3)cc2)c1 +O=C(NCCc1nc(-c2ccccn2)cs1)c1ccc(=O)[nH]c1 +CCCN(C)C(=O)Nc1ccc(C)c(C(=O)NC(C)C)c1 +CN(Cc1cccnc1)C(=O)c1ccc(-c2ccccc2)[nH]1 +CC1CC(C(N)=O)c2ccccc2N1C(=O)Cc1noc2ccccc12 +CCOC(=O)c1c(C)nn(Cc2ccccc2)c1N +CCCNC(=O)Cn1cnc2c(nnn2-c2cc(C)cc(C)c2)c1=O +CCN(CCO)C(=O)c1ccc2c(c1)[nH]c(=O)c(=O)n2CC +Cc1csc2nc(CSc3nncs3)cc(=O)n12 +Cn1ccc2ccc(C(=O)NCc3nnc4ccccn34)cc21 +CCN(C1CC1)S(=O)(=O)c1cccc(-n2cnnn2)c1 +CC(=O)NC(C)C(=O)N(C)Cc1c(C)nc2sc(C)cn12 +O=C(c1cnn(S(=O)(=O)c2ccccc2)c1)c1cc(F)ccc1O +Cc1nc(CCNC(=O)NC(C)c2ccccn2)cs1 +CCN(CC(C)C#N)C(=O)CSc1ncnc2ccsc12 +CCCCc1noc(CS(=O)(=O)c2ccc(O)cc2)n1 +Cc1ccc(C(C)NC(=O)Cn2c(C)c(C)sc2=O)o1 +CS(=O)(=O)c1ccc(NC(=O)c2cccc(Cl)c2)cc1C#N +COc1cccc(NC(=O)c2ccc(-c3ccco3)o2)c1 +OC(CNCc1cccnc1)c1cccc(Cl)c1 +CC1CCC(NC(=O)c2ccc(F)c(N)c2)CC1 +O=C(OCCN1CCCC1=O)C1CC(=O)N(CC(F)(F)F)C1 +COCCCOc1ccccc1NC(=O)c1cccs1 +COc1ccc(CC(=O)NCC(C)(O)C2CC2)cc1OC +COc1ccc(CNc2ncnc3[nH]nc(SC)c23)cc1 +Oc1ccc(F)c2c1CCNC2C(O)c1ccccc1F +CCc1n[nH]c(CC)c1NC(=O)c1cccc(OC)c1 +O=S(=O)(Cc1nnnn1-c1ccccc1)c1ccccn1 +O=C(Nc1cccnc1)Nc1cccc2ccccc12 +CC(C)(C)c1ccc(C(=O)NCCC(=O)NCC(F)(F)F)cc1 +O=C(Cn1cc(NC(=O)NCCc2ccccc2)cn1)NC1CC1 +CCC(=O)Nc1ccc(C(=O)NCC(C)C)c(Cl)c1 +c1ccc(OCc2nnc(COc3ccccc3)nn2)cc1 +CCCC(=O)NCCNc1cc(N2CCCC2)nc(C)n1 +CCOc1cc(C(C#N)N2CCOCC2)ccc1O +Cc1ccc(-c2c(C#N)nnn2CCCO)cc1C +COc1cccc(NC(=O)c2cn(C)c3ccccc3c2=O)c1 +CCNC(=O)COc1ccc(N(C)C(=O)NC(C)C)cc1 +CCc1cc2c(NCc3cccc(O)c3)ncnc2s1 +NC(=O)C1CCN(C(=O)CCCc2ccccc2)CC1 +COc1ccc(Br)cc1NCc1csc(C)n1 +Cc1cc(N)ccc1S(=O)(=O)NCCC(N)=O +Cc1n[nH]c(C(=O)N2CCCC2)c1Br +NC(=O)c1cccc(COC(=O)c2ccc(C(F)(F)F)cc2)c1 +COC(=O)CCC(=O)Nc1ccc(CC(N)=O)cc1 +O=C(Nc1cccnc1)C1CC(=O)N(c2ccc(F)c(Cl)c2)C1 +COc1nn(C)cc1C(=O)N1CCN(CCNC(=O)C2CC2)CC1 +Nc1nc(-c2ccccn2)ncc1C(=O)NC1CCCCC1 +COC(=O)c1cccc(NC(=O)C2CC(=O)Nc3ccccc32)c1C +COc1cccc(NC(=O)N2CCN(Cc3ccccc3C)CC2)c1 +COC(=O)c1ccc2c(c1)C(c1ccc[nH]c1=O)NCC2 +CC(C)c1cc(C(=O)OCC2CCC(=O)N2)c2cnn(C(C)C)c2n1 +CCc1cc(C)c(C(=O)N(C)Cc2c(C)nc3sc(C)cn23)o1 +FC(F)(F)c1ccc(-n2cc(Br)cn2)cc1 +COCCN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(C)ccc1F +O=C1CCN(C(=O)c2cc(Br)ccc2F)CCN1 +CC(C)Oc1ccccc1NC(=O)NCC(=O)Nc1ccccc1 +CCN(CC)C(=O)C(C#N)CCOc1ccc(Cl)cc1 +Cc1cc(C)c(C(=O)NCCS(=O)(=O)N2CCOCC2)c(C)c1 +CCCOC(=O)Cn1c(CC)nc2c(N)cccc21 +COc1ccccc1OCC(=O)Nc1nc(C(C)C)cs1 +Cc1ccc(N(CC(=O)N2CCCCC2)C(=O)c2ccoc2)cc1 +Cc1n[nH]c(SC(C)C(=O)Nc2ccccc2C#N)n1 +Cc1cc(C)c(C#N)c(N2CCN(c3ccc(F)cc3)CC2)n1 +N#Cc1ccc(N2CC3OCC(=O)N(Cc4ccccc4)C3C2)nc1 +O=C1NC(C(F)F)Cc2ccc(C(F)(F)F)cc21 +CCN(CC)S(=O)(=O)c1ccc(=O)n(CC(=O)NC(C)(C)C)c1 +COCC(C)NC(=O)c1sc(C(C)C)nc1C +CC(C)(C)NC(=O)CSc1nc2ncccc2o1 +O=C(c1cnccn1)N1CC2CC(c3nc(C4CC4)cs3)OC2C1 +COc1cccc(C(=O)NCc2ccn(C)c2)c1F +COc1ccc(C)cc1NC(=O)CSc1nc(C)cs1 +O=c1ccc(=O)c2sc3c(=O)ccc(=O)c3sc12 +CC(O)CNS(=O)(=O)c1ccc(F)c(Cl)c1 +O=C(CSc1nnnn1C1CCCC1)c1ccccc1F +Cc1occc1COC(=O)C(C)NC(=O)c1ccco1 +COc1ccc(Nc2nn[nH]c2C(=O)NCc2ccccc2)cc1 +CCOC(=O)CN1CCN(C(=O)Nc2ccc(C)cc2)CC1=O +COc1cccc(COC(=O)CCn2c(=O)oc3ccccc32)c1 +Cc1cc(C)n2c(CCCNS(=O)(=O)c3ccccc3)nnc2n1 +N#CCc1ccc(NC(=O)NCCC(=O)N2CCCCC2)cc1 +Cc1cc(NC(=O)c2ccc3c(c2)nc(C)n3C)c2ncccc2c1 +COC(=O)C1CCN(S(=O)(=O)c2cn[nH]c2)CC1 +Cc1ccc2ncn(Cc3coc(-c4cccs4)n3)c(=O)c2c1 +Cc1ccc(OC(=O)C2CCN(C(=O)N(C)C)CC2)cc1 +N#Cc1cccc(C2NCCc3cc(O)ccc32)c1 +O=C(NCCCNC(=O)c1scc2c1OCO2)c1cccs1 +Cc1cccc(-c2cccc(CNC(=O)c3ccc(=O)n(C)n3)c2)c1 +CC(C(=O)NCc1cc(Cl)c2c(c1)OCCO2)c1ccsc1 +C=CCc1ccccc1OC(=O)CCn1ncc(=O)c2ccccc21 +CCn1ccc(C(=O)Nc2nnc(-c3cc(C)n(C)n3)o2)n1 +Cn1cc(CCOC(=O)c2csc(-c3cnn(C)c3)n2)cn1 +O=C(c1ccco1)N1CC2OCCN(c3cnccn3)C2C1 +COc1nc(OC)nc(C2=CC3=CC=NC3C=C2)n1 +O=C(N1CCCCCC1)N1CCN(c2ccccc2F)CC1 +CCCNC(=O)N(CCC(N)=O)Cc1ccccc1 +O=C(OCc1nc(-c2cccnc2)no1)c1ccc(-n2cncn2)cc1 +Cc1n[nH]c(C)c1C1CCCN1C(=O)Cc1cccc(F)c1 +CCCCC(Sc1nncn1C)C(=O)Nc1cc(C)on1 +COCCNC(=O)C(C)n1c2ccccc2c2cnn(C)c(=O)c21 +CCC(C)(CNC(=O)NCCc1csc(C)n1)N1CCOCC1 +COC(=O)c1cccc(CCNC(=O)NCc2ncccc2C)c1 +COC(=O)c1cc(S(=O)(=O)N(C)C)ccc1Cl +Cc1nnc(CNCc2cccc3c2OCCO3)s1 +CCCCCC(C)NC(=O)Cn1cnc2ccccc21 +COc1ccc(Cl)cc1C(O)CNS(C)(=O)=O +O=C(NCCc1cccc2cccnc12)Nc1cccc2cnccc12 +CCOc1ccccc1C(=O)CCc1nc(C)cs1 +CCOCCCNC(=O)c1cc(-c2ccccc2F)on1 +Cc1cc(C(=O)NCCc2c[nH]c3ccccc23)c(C)n1C1CC1 +CC(C)CCOc1ccc(OCC(=O)N2CCN(C)CC2)cc1 +COC(=O)C1OC(n2cnc3c(N)ncnc32)C(O)C1O +CCCCn1c(-c2ccc(OC)c(C)c2)ccc(CO)c1=O +CCCCN(c1ccc(C#N)cc1)S(C)(=O)=O +CN(C)C(=O)CSc1nnc(N2CCOCC2)n1-c1ccccc1 +CCC(C)OC(=O)n1ccc(C(=O)Nc2cc(C)ccn2)n1 +CS(=O)(=O)c1cccc(S(=O)(=O)Nc2ccccc2)c1 +CCNC(=O)CCC(=O)c1cc(F)ccc1OC +C=CCN(C(=O)CCn1nnc2ccccc2c1=O)c1ccccc1 +Cc1ccc2ncc(C(=O)Nc3ccc4[nH]c(=O)[nH]c4c3)n2c1 +CCCC(C(=O)Nc1cccc(C(N)=O)c1)c1ccccc1 +Cn1c(=O)ccn(CC(=O)N2CCc3ccccc3C2)c1=O +Cc1[nH]c2ccnn2c(=O)c1CC(=O)NCC1CCC(C)(C)CC1 +COC(=O)C1CCN(C(=O)Nc2ccccc2F)CC1 +COc1ccc(CCNC(=O)c2cc3c(cn2)OCC3)cc1OC +COCC(C)NC(=O)CSc1nc2ccccc2c(=O)n1C +COC(=O)c1cc(CNC(=O)c2c(C)nn(C)c2C)ccc1OC +Cc1c(C(=O)N2CCC(Oc3cccnc3)C2)cnn1-c1ccncc1 +O=C(NCCc1nc(-c2cccnc2)n[nH]1)c1cccc2cccnc12 +N#Cc1cccc(C(=O)N2CCN(CCOc3ccccc3)CC2)c1 +Cc1cccc(N(C)C(=O)Cn2c(=O)oc3cc(Cl)ccc32)c1 +COCc1ccccc1NCC(=O)Nc1ccc(C(=O)N(C)C)cc1 +CCN1CC(C(=O)Oc2ccc(OCC3CC3)cc2)CC1=O +CN(C(=O)c1cn(C)nc1C(F)(F)F)c1ccc(F)c(F)c1 +Cc1csc(CN(C)S(=O)(=O)c2cccc3ccc(C)nc23)n1 +Nc1c(Cl)ccc2c(NC3CCCC3)nccc12 +CC(C)(C)c1nc(CSc2nnc(-c3ccc[nH]3)o2)no1 +O=C(Nc1cnc(N2CCCCC2)nc1)c1cccs1 +CCOC(=O)c1nnc2c(-c3cccc(Cl)c3)c(CC)nn2c1N +COc1ccc(-c2cc(CC(=O)Nc3cc(C)on3)no2)cc1 +CC(CNC(=O)NCc1ncn(C)n1)c1c(Cl)cccc1Cl +CC(C)(C)OC(=O)N1CCC(c2nc3ccccc3cc2N)CC1 +COc1ccc(S(N)(=O)=O)c(Cl)c1Cl +COc1ccc(Cl)cc1S(=O)(=O)NC(C)C#N +Cc1ccccc1C(=O)N1CCC(CCOc2cccnc2)CC1 +O=C(c1ccc(O)cc1)C1CCN(C(=O)Nc2ccccn2)CC1 +CNC(=O)c1cnc(COc2cccc(C)c2)nc1N +O=C(c1ccccn1)N1CCc2cc(F)ccc2C1 +O=C(Cn1nc(-c2cccs2)oc1=O)c1ccc(F)cc1 +Cc1nc(C(F)(F)F)nc(N2CC(c3ccccn3)C2)c1C +C=CCCCN(C)C(=O)NCC(C)(C)c1ccncc1 +Cc1n[nH]cc1CNC(=O)c1csc(-c2ccsc2)n1 +COc1cccc(CNC(=O)c2ccc(Oc3nccs3)cc2)c1 +COC(=O)c1ccc(CNC(=O)CCNC(C)=O)cc1 +O=C(c1nc(-c2ccc(N3CCOCC3)cc2)no1)N1CCCC1 +C#Cc1cccc(N(CC(=O)NC)Cc2nnc(C3CC3)n2C)c1 +COc1ccc(Cl)cc1C(=O)NCC(O)c1ccc2c(c1)CCO2 +CC(NC(=O)C1CC=CC1)c1nnc2ccccn12 +Fc1ccc(NCc2ccc3c(c2)OCCO3)cc1Cl +O=C(CN1CCOC(c2ccc(F)cc2)C1)NC1CC1 +CCCNC(=O)CN(C)C(=O)Nc1ccc(C#N)c(Cl)c1 +Cc1ccnc(NC(=O)Cn2ccc3c(=O)n(C)c(=O)n(C)c32)c1 +Cc1nn(C)c2ncc(NC(=O)c3ccc(-n4ccnc4)nc3)cc12 +CC(=O)Nc1ccc(N2CC(C(=O)NCC3CCCO3)CC2=O)cc1 +COc1ccc(OC)c(C(=O)CCC(=O)N2CCCCC2)c1 +CC1=CC(C)(C)Nc2ccc(OS(C)(=O)=O)cc21 +CN(Cc1ccccc1Cl)C(=O)c1cc(Cl)ccn1 +CCOCCCNS(=O)(=O)c1c(C)cc(C)cc1C +O=C(c1ccncc1)N1CCN2CC(OCc3ccccn3)CC2C1 +Cc1oc(-c2ccccc2)nc1C(=O)NCC(=O)NCc1ccco1 +C#CCOCC1CCCN(C(=O)CCc2ccccc2)C1 +CCCC(=O)Nc1cccc(NC(=O)CCn2c(C)csc2=O)c1 +CNC(=O)c1cc2c(s1)CCN(C(=O)c1c(C)cc(C)[nH]c1=O)C2 +CSc1ccccc1C(=O)Nc1sc2c(c1C#N)CCC2 +O=C(Cc1ccccc1)NCC(=O)NC1CCCC(C(F)(F)F)C1 +CC(=O)c1cccc(NCC(=O)N(CCC#N)c2cccc(C)c2C)c1 +Cc1ccc(NC(=O)C(C)OC(=O)c2cnn(C)c2C)cc1 +COc1ccc(OC)c(NC(=O)CCSc2cc(C)ncn2)c1 +CC(C)c1noc(CCCC(=O)NCc2ccccc2)n1 +CCCOC(=O)C(C)n1c(=O)c(C)nc2ccc(N)cc21 +COCCN(Cc1ccsc1)S(=O)(=O)c1ccc(C)cc1C +O=C(NCc1nc(-c2cccc(Cl)c2)no1)NCC(F)(F)F +CC(=O)N1CCN(C(=O)C(C)Oc2ccc(C)c(C)c2)CC1 +CC(O)CN(C)S(=O)(=O)c1cccc(C(C)O)c1 +CCc1nnc(C(C)Sc2ncnc3sc(C)cc23)o1 +COc1ccc(S(=O)(=O)Nc2cccnc2)c2ccccc12 +CCOC(=O)c1ccsc1NC(=O)c1sc(C)nc1C +COc1cc(N)ccc1NC(=O)COc1cc(C)c(Cl)c(C)c1 +CCn1c(NC(=O)CCn2c(C)csc2=O)nc2ccccc21 +O=C(Nc1ccccc1)OCc1cc2cccc3c2n(c1=O)CCC3 +CCOC(=O)c1nn(CCCN2CCOCC2)c(N)c1C#N +CCOc1cc(C(=O)N2CCCC(c3cc(C(N)=O)[nH]n3)C2)ccn1 +CCC(C)n1ncc(C(=O)Nc2cccc(C(=O)NC)n2)c1C1CC1 +Cc1nn(C)c(C)c1CCC(=O)Nc1c(C(=O)N(C)C)nn(C)c1C +Cc1cnc(NC(=O)N2CCN(c3ccccc3)CC2)s1 +Cc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1F +NC(=O)c1cccc(S(=O)(=O)N2CCCc3cc(F)ccc32)c1 +Clc1ccc2c(c1)CN(Cc1nc(-c3ccoc3)no1)CC2 +CC(C)COc1ccc(CC(=O)Nc2cc(C(N)=O)n(C)c2)cc1 +O=C(Nc1ccc(OCC(=O)N2CCCC2)cc1)C1CC1 +COc1ccc(-n2nc(C(=O)NC3CC3)nc2-c2ccccc2)cc1 +COc1ccc(OC)c(NC(=O)N2CCCC2CO)c1 +CCC1c2ccsc2CCN1C(=O)c1cccc2ncccc12 +Cc1ncccc1C(=O)N1CC=C(c2ccccc2Cl)CC1 +Cc1ccc(-c2cn(C3CCN(C(=O)C4CCCO4)CC3)nn2)cc1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1nnc2ccccc2n1 +CCCOc1ncccc1CNC(=O)Nc1cccc(SC)c1 +c1ccc2c(c1)nnn2CCCn1nnc2ccccc21 +Cc1cccc(C)c1OCCOC(=O)Cc1c(C)nn(C)c1C +COC(=O)CC(NC(=O)c1cc2ccccc2o1)C1CC1 +CCc1ccccc1NC(=O)c1cc(C(C)=O)cn1C +CC(Sc1cccc(Cl)c1)C(=O)Nc1sccc1C(N)=O +O=c1[nH]nc(SCC2CCCCO2)n1CCc1ccccc1 +O=C(Cn1cc(Br)ccc1=O)N1CCNCC1 +CCc1onc(C)c1NC(=O)c1nc2nc(C)cc(C)n2n1 +COCCNC(=O)c1ccccc1OCc1c(C)noc1C +O=C1CC(C(=O)Nc2ccc(Cl)cn2)c2ccccc2N1 +CCC(O)CN1CCN(C(=O)COc2ccccc2OC)CC1 +CNc1ncccc1C(=O)N1CCN(S(=O)(=O)N(C)C)CC1 +N#Cc1ccc(S(=O)(=O)Nc2ccc(F)cc2)cc1 +CCc1sc(C(=O)NCCCN2CCOCC2)cc1C +CCOc1ccc(NC(=O)N(C)C(C)CC#N)cc1 +Cc1ccc(C)c(N2CC(C(=O)NCc3ccco3)CC2=O)c1 +Cc1cc(C)n(CCNc2nc3nonc3nc2N2CCCCC2)n1 +Cn1nnn(-c2ccc(NC(=O)C3CCCC3)cc2)c1=O +O=C(CCc1nc(-c2cccs2)no1)Oc1ccc2cn[nH]c2c1 +Cc1ccc(C(N)=O)cc1-c1ccc(C(N)=O)c(Cl)c1 +CCCCC(NC(=O)c1oc(CC)nc1C)C(N)=O +O=C(CNC(=O)c1ccc(F)cc1)OCc1nnc(-c2ccco2)o1 +C1=C(CN2CCCN(c3cccnn3)CC2)COCC1 +CCNC(=O)CN(CC)C(=O)Nc1cccc(N)c1 +CCCOC(=O)c1cccc(NCc2c(C)noc2C)c1 +CC(C)(CO)NC(=O)Nc1ccc(Oc2ccc(C#N)cc2)cc1 +CCc1ccc(C(=O)N(C)Cc2ccccc2F)cc1 +CC(C)COC(=O)c1ccc(CNC(N)=O)cc1 +O=C(c1ccc(Cn2cc(Cl)cn2)o1)N1CCCCC1 +COc1ccc(OC)c(C(=O)CCC(=O)NC2CC2)c1 +Cc1noc(C2CCC3C(CCN3S(=O)(=O)C3CC3)O2)n1 +Cc1c[nH]cc1C(=O)N1CCN(CCc2cccs2)CC1 +CC(C)CCNc1ncnc(NCC2CCCO2)c1N +Cc1c2n(c3ccccc3c1=O)C(=O)c1ccccc1-2 +CCOC(C)C(=O)Oc1cccc(NC(=O)c2ccccc2)c1 +O=C1OC(C(=O)NCc2ccc3c(c2)OCCO3)Cc2ccccc21 +O=C1CCN(C(=O)c2cccc(OCC(F)F)n2)c2ccccc2N1 +COc1ccccc1CC(=O)N1CCNc2ccccc2C1 +CCn1cc(C(=O)NCc2cccc(Cn3cccn3)c2)cn1 +CNC(=O)C1(N(C)Cc2ccccc2)Cc2ccccc2C1 +Cc1ccc(OCC#CCN2CCOCC2)cc1C +COc1ccc(-c2nc(-c3ccccn3)nn2CCO)c(OC)c1 +Cc1nc(Nc2nc3ccccc3o2)ncc1C(=O)Nc1ccccc1 +Cc1ccccc1CC(=O)N1CCN(C)C2(CCNC(=O)CC2)C1 +COc1cc(CO)cc(Br)c1OCC1CCCO1 +C#CCN(CC#C)Cc1cc(OC)cc2c1OC(C)C2 +CCNC(=O)C(C)n1nc(-c2ccc(F)cc2)ccc1=O +Cc1ccc(C(=O)NCc2cccc(OCC(=O)N(C)C)c2)c(C)c1 +CCCC1CN(C(=O)c2ccc(OCC3CCCO3)cc2)CCO1 +COc1ccc(CNC(=O)N2CCC(C(N)=O)CC2)cc1OC +O=C1CCCc2c1cnc1c2c(=O)[nH]c(=O)n1CCc1ccccc1 +O=C(Cc1nnc(-c2ccsc2)o1)Nc1cc(F)cc(F)c1 +COC(=O)c1c(NC(=O)COC(=O)C2CCC2)sc(C)c1C +CN(CCOCC1CC1)C(=O)c1cc(Br)c[nH]1 +NC(=O)c1ccc(CNc2ncc(C(F)(F)F)cc2Cl)cc1 +NC(=O)Nc1ccc(Oc2ccc(F)cc2F)nc1 +CC1(C)CCCN1C(=O)CCc1nc2ccccc2s1 +CN(C)S(=O)(=O)c1cccc(NC(=O)CCn2ccccc2=O)c1 +Cc1ccc(-c2csc3nc(C)n(N)c(=O)c23)cc1C +CC(=O)N1CCCN(S(=O)(=O)c2ccc(Cl)cc2F)CC1 +O=C(c1cccc2ncccc12)N1CCN(C2CCCC2O)CC1 +CCOCCCNC(=O)c1cnn(-c2ccccc2Cl)c1 +Cc1ccc(CN(C)C(=O)c2ccc(-n3ccnc3)cc2)o1 +Cc1ccc(F)c(NC(=O)c2nn(-c3ccccc3)c(C)cc2=O)c1 +OCCN1CCN(CCOc2ccc3ccccc3c2)CC1 +CC(C)(C)c1ccc(C(=O)c2c[nH]c(C(N)=O)c2)cc1 +CC(=O)NCCCSc1nc2ccccc2c(=O)n1C(C)C +CC(C)Cc1nnc(NC(=O)CCNC(=O)c2ccsc2)s1 +CN(C)C(=O)Sc1cnc2c(c1)c(=O)n(C)c(=O)n2C +CNc1cc(CNC(=O)Cc2cccnc2)nc(-c2ccncc2)n1 +Cc1nn(CCOc2ccccc2F)c(=O)c(C#N)c1C +Cc1sc(=O)n(CC(=O)N(C)Cc2ccco2)c1C +FC(F)(F)c1cccc(Cn2nnc(-c3cccnc3)n2)c1 +CC(C)Cc1noc(CN(C)Cc2coc(C(C)C)n2)n1 +Cc1nc(Nc2cccc(N)c2)cc(-c2ccccc2)n1 +Cc1ccc(NC(=O)C(C)C)cc1NC(=O)c1ccc(=O)n(C)c1 +CN(Cc1ccncc1)C(=O)c1ccc(C(=O)OC(C)(C)C)cc1 +Nc1n[nH]c2nc3c(c(-c4cccs4)c12)CCC3 +CCNc1nc(-c2ccc3c(c2)C(C)C(=O)N3)cs1 +O=C(c1cccnc1)N1CCCC(c2ccc(-c3cncnc3)cn2)C1 +COc1ccc(-c2nc(CNC(=O)c3ccc(C)nc3)n[nH]2)cc1 +CSc1nn(-c2nc3c(C)cccc3s2)c(N)c1C#N +CCc1ccc(C(=O)N2CCCC(n3nc(C)nc3C)C2)cc1 +CCc1ccc(CNC(=O)c2cnn(C(C)C)c2C(F)(F)F)s1 +COc1ccc(OC)c(C(C#N)N(C)S(C)(=O)=O)c1 +Cn1cnnc1C1CCCN(C(=O)CCOc2ccc(F)cc2)C1 +c1ccc2nc(CSc3nnnn3CC3CCCO3)ccc2c1 +Cc1ccc(N2CC(C(=O)Nc3ncc(Cl)cc3C)CC2=O)cc1 +CCCCNC(=O)Nc1ccccc1C(=O)N1CC(C)CC(C)C1 +O=C(Nc1nc(CN2CCc3ccccc3C2)cs1)c1ccccc1 +c1cnc(N2CCN(c3ncnc4sc5c(c34)CCC5)CC2)nc1 +CCOC(=O)C(C)NS(=O)(=O)c1c(C)n[nH]c1C +Cc1csc(-c2cccc(NC(=O)Nc3cnn(C)c3)c2)n1 +COc1ccc(C(=O)Nc2cc(Cl)ccc2N(C)C)nn1 +CCOC(=O)N1CCC(OC(=O)c2cc(-c3ccccc3)on2)CC1 +CCc1cc(C(=O)N2CCN(CC(=O)NC)CC2)[nH]n1 +CCc1ccc(S(=O)(=O)N=c2[nH]cccc2CO)cc1 +O=C1c2ccccc2NC(c2ccncc2)N1c1ccccn1 +COc1cccc(-c2nnc3sc(NC(=O)C(C)C)nn23)c1 +COC(=O)CN(Cc1cccc(-c2ccccn2)c1)C(C)C +CC(Sc1nnc(-c2ccncc2)n1C1CC1)C(=O)OC(C)(C)C +CCCOc1c(OC)ccc2c1C(c1ccncc1)NCC2 +COc1ccc(F)c(F)c1-c1nccn1CCNc1cccnc1 +Oc1cc2c(cc1F)CCNC2c1nccc2ccccc12 +N#Cc1ccc(OCCOC(=O)Cn2cnnn2)cc1 +O=C(COc1ccc2c(c1)CCC2)NC1CCCc2[nH]c(=O)ccc21 +O=C1CC(c2ccccc2)CN1CC(=O)N1CCOC2(CCCC2)C1 +Cc1cccc(NC(=O)c2c(C)oc3nc[nH]c(=O)c23)c1C +O=C(CCn1cccn1)NC1(c2ccc(F)cc2F)CCCC1 +Cc1cccc(C(=O)N2CCC(c3ccsc3)CC2)c1 +COC(=O)CCCS(=O)(=O)N=c1[nH]c(C)cs1 +N#Cc1ccc(OC2CCC(NC(=O)Cn3ccnc3)CC2)nc1 +Cc1nnsc1CNc1nccc(C(F)(F)F)n1 +COCc1nc(CNC(=O)c2ccc(-n3nc(C)cc3C)cc2)no1 +O=C(Cn1c(=O)[nH]c2ccccc21)Oc1ccc(Br)cc1 +CCCC(=O)Nc1cccc(NC(=O)c2cc(OC)cc(OC)c2)c1 +O=C(CCC1CCCC1)NC1CCN(c2ccccc2)C1=O +NC(=O)CC1CCN(C(=O)CCc2cccc(Cl)c2Cl)CC1 +CN1CC(C(=O)N2CCCc3ccccc32)CC1=O +Cn1ccc(C(=O)Oc2cc(Cl)cc(Cl)c2)cc1=O +NC(=O)NC(CC(=O)N1CCCC1)c1cccs1 +Cc1cc(C2CCCN(S(=O)(=O)N(C)C)C2)ccn1 +CCOc1ccccc1C(=O)Nc1cc(F)c(F)cc1NC(C)=O +O=C(CCNC(=O)c1ccc(N2CCOCC2)nc1)NC1CCCC1 +Cc1cc(C)n(-c2ncnc(-n3nc(C)cc3C)c2N)n1 +O=C(NC1CCCNC1=O)c1ccc(O)c(Cl)c1 +O=C(NC1CCN(c2c(F)cccc2F)C1)C1CC=CCC1 +CCC1CCCN(C(=O)c2cc(OC)c(S(N)(=O)=O)s2)C1 +O=C(c1ccc(CO)cc1)N1CCCCC1CCc1cccs1 +CC(=O)NC(C)C(=O)N1CCCC(C(F)(F)F)C1 +N#CCn1c(N)nnc1SCCc1ccccc1 +Cc1nc(CN2CCN(C(=O)NCC(C)C)CC2)cs1 +COCC(=O)N(C)CC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cc1cccc(CNC(=O)N2CCC(c3nnc4ccccn34)CC2)c1 +COCCN(C)S(=O)(=O)c1cc(Br)ccc1OC +CC1CCCCN1c1nc(N)c2c(n1)CC(C)(C)CC2=O +COc1ccc2nc(NC(=O)COc3ccccc3F)sc2c1 +CC(C(=O)Nc1cc(Cl)ccc1Cl)n1cc(N)ccc1=O +O=C1CC(C(=O)Nc2ccc3c(c2)OCO3)c2ccccc21 +Cc1cc(C)c(NC(=O)CCc2nc3ccccc3[nH]c2=O)c(C)c1 +Cc1ccnc(NC(=O)c2ccc(COc3ccc(C#N)cc3)o2)c1 +Cn1cc(CCNS(=O)(=O)c2ccc(Cl)cc2)c2cccnc21 +C#Cc1cccc(NC(=O)CNC(=O)c2cc(C)n(C3CC3)c2C)c1 +COc1ccc(NC(=O)c2cc(C)no2)c2ccccc12 +O=C(Cn1nnc(-c2cccs2)n1)NCCC1CCCCC1 +N#Cc1ccc(S(=O)(=O)Oc2ccc(NC(=O)C3CC3)cc2)cc1 +COCCN1COc2ccc3c(C)c(CC(=O)OC)c(=O)oc3c2C1 +CC(C)c1ccc(S(=O)(=O)C(C#N)c2nc3ccccc3[nH]2)cc1 +CC(=O)NCC(=O)NCCCOc1c(C)cccc1C +CCN1CCN(Cc2nc(Cc3ccccc3Cl)no2)C(=O)C1=O +CC(=O)NC1CCN(C(=O)c2ccc3c(c2O)OC(C)(C)C3)CC1 +O=C(NCc1ccoc1)Nc1cc(Cl)cc(Cl)c1 +O=C(NCc1ccncc1)c1ccc(-c2ccccc2Cl)o1 +COc1ccc(NC(=O)CC(NC(N)=O)c2ccccc2)cc1 +Cc1cc(-c2nc(-c3ccc(C#N)cn3)no2)c2ccc(F)cc2n1 +Cc1ccc(-c2nc(C(=O)NCCS(N)(=O)=O)cs2)cc1 +CCn1nnc2cc(C(=O)OCc3nnnn3-c3ccccc3)ccc21 +N#Cc1cccc(S(=O)(=O)c2cnc3ccc(F)cc3c2Cl)c1 +Cc1cnn(-c2ccncc2NC(=O)c2cnc3ccc(C)cn23)c1 +CC(C)c1nn2c(=O)cc(CSc3ccccc3N)nc2s1 +Cc1cccc(C)c1OC1CN(C(=O)C2CCC(O)CC2)C1 +COc1cc(C2CC(=O)NC3=NC(C)=NC(=O)C32)cc(OC)c1OC +Cc1nc(C(=O)NC(C)c2nncn2C)cs1 +CSc1ccc(C2NCCc3c(F)cc(O)cc32)cc1 +Cc1cc(NC(=O)c2cccc(F)c2)nc2nc(C(F)(F)F)nn12 +Cc1ccc(C)n1-c1c(C(=O)NC2CC2)cnn1C +CN(CCC(F)(F)F)C(=O)NCc1ccccn1 +COCCn1cc(NS(=O)(=O)c2ccc(F)c(Cl)c2)cn1 +Cc1cccc(C(N)C(F)(F)F)c1Br +CCCOCCC(=O)Nc1ccc(Br)cc1N +Cc1ccccc1OCC(=O)Nc1cccc2c1OCCO2 +Cn1c(C(=O)Nc2ccc(-n3ccnc3)cc2)cc2ccc(F)cc21 +CCNc1nnc(SCC(O)c2ccc(F)cc2F)s1 +Cc1cc(NC(=O)C(C)(C)C)sc1C(=O)N(C)CC(=O)N(C)C +COC(=O)N1CCC(CNS(=O)(=O)c2cc(F)cc(F)c2)CC1 +COc1ccc(CCC(=O)NC2CCc3ccccc32)cc1OC +CC(=O)N1CCC(NC(=O)CCOc2cccc(Cl)c2)CC1 +N#Cc1ccc(OCCN2CCN(C(=O)c3ccccc3)CC2)cc1 +CC(C)c1noc(-c2ccccc2C(=O)N(C)c2nccs2)n1 +CC(C)(C)C(=O)N1CCC(C(=O)Oc2cccc(F)c2)CC1 +Cc1ccncc1NC(=O)N1CCN(C(=O)OC(C)(C)C)CC1 +CC(C)NC(=O)N1CCC(S(=O)(=O)c2ccccc2)C1 +COc1ccc(C#N)cc1Cn1nc(C(F)(F)F)c2cnccc21 +CCNC(=O)c1cc(Cl)ccc1NCC(=O)N1CCCC(C)C1 +O=C(NCCc1ccccn1)c1ccc(OCC2CCCO2)cc1 +Cc1cc(SCC(=O)N(C2=CCCCC2)C2CC2)nc(C)n1 +Cc1nc(C)n(CCCNC(=O)CCc2scnc2C)n1 +Cn1cc(C(=O)OCC(=O)NC2CCCC2)c2ccccc21 +Cc1ccsc1C(=O)N1CC(NS(C)(=O)=O)C2OCCCC21 +O=C(Nc1ccc(CCN2CCOCC2)cc1)c1ccncc1F +Cc1ccc(C(=O)N2CCOC(COc3ccccc3F)C2)cc1 +O=C(NCCc1nccs1)Nc1ccnn1Cc1ccccc1F +Cc1ccc(NC(=O)Cn2nnc3ccccc3c2=O)cc1Cl +Cc1n[nH]c(SCc2ccc(NC(=O)C(C)C)cc2)n1 +CCCc1noc(CCC(=O)Nc2ccccn2)n1 +COCCn1nc(C(=O)N2CCCC(n3cncn3)C2)ccc1=O +CC(C)(C)Oc1cc(CNC(=O)C2CC(=O)C2)ccn1 +Cc1nc2c(C(=O)N3Cc4cnc(C(C)(C)C)nc4C3)cccc2[nH]1 +Cc1cccc(OC(=O)Cn2nnc(-c3ccccc3)n2)c1C +CCc1nc(CSc2nnc(N)n2C(C)C)no1 +O=C(Cc1ccc(C(F)(F)F)cc1)N1CCC2(CCCNC2=O)C1 +CN(C(=O)c1cc(F)cc(Br)c1)C1(C#N)CCC1 +CCNc1ncc(S(=O)(=O)NC(C)C(C)CC)cn1 +Cc1nnc(SCCCNC(=O)c2nccc3ccccc23)s1 +CC(=O)NCc1ccc(C(=O)NCC2(c3ccccc3)CCC2)cc1 +NC(=O)N1CCC(C(=O)OCc2nnc(-c3ccc(F)cc3)o2)CC1 +CC(C)(CN1CCN2C(=O)C(=O)NCC2C1)c1ccccc1 +CC(=O)c1c(SCCCC(=O)c2ccccc2)nc(=O)[nH]c1C +Cc1ccc(C)c(C(=O)CCC(=O)Nc2nncs2)c1 +Cc1csc(NC(=O)c2csc(Cc3ccccc3)n2)n1 +O=C(NCC(O)c1cccc(OC(F)F)c1)c1cc(F)ccc1F +CC1CC1C(=O)NCCC(=O)N(Cc1ccccn1)C(C)C +Cc1cc(C(=O)Nc2ccc(OCC(=O)N(C)C)cc2)n(C)n1 +Cc1ccc(C(=O)Nc2ccccc2OC(F)F)o1 +Cc1oc(C(N)=O)cc1C(=O)CSc1nccn1C +O=C(NCC1(O)CCOc2ccccc21)c1ccccc1Cl +CC(=O)c1ccc(NC(=O)Cn2c(=O)cc(C)c3cccc(C)c32)cc1 +CCN(Cc1ccccc1)S(=O)(=O)Cc1cc(C#N)ccc1F +CCCCc1nnc2sc(-c3ccc(N)cc3)nn12 +O=C(NCCCCCO)c1ccc2nc(-c3ccc(F)cc3)cn2c1 +Cc1nc(N2CCCN(c3ncccn3)CC2)c2cnn(C)c2n1 +Cc1noc(C)c1CCC(=O)NCCOc1ccc(F)cc1 +CCOc1ccc(-c2nnc(SCC(=O)NC(C)(C)C)n2N)cc1 +Cc1cc(C)nc(SCC(=O)Nc2cccnc2N(C)C)n1 +CCCCNC(=O)NCc1cccc(NC(C)=O)c1 +COCC(=O)N1CCCc2ccc(NC(=O)C(C)C)cc21 +O=C(Nc1ccccn1)c1ccc(-c2noc(C3CCCC3)n2)cc1 +Cn1nnc(NC(=O)c2cccc3ccccc23)n1 +NC(=O)C1(NC(=O)c2cc(-c3ccccc3Cl)[nH]n2)CCCCC1 +CC1CN(C(=O)CCCc2cccs2)CC(C)O1 +COc1cccc(OCC2CCCN(C(=O)CCn3cnnc3)C2)c1 +COC(=O)CCc1c(C)nn(-c2ccc(C(=O)OC)cc2)c1C +CCOCCSc1nnc(-c2ccc(C)cc2)o1 +Cc1cnc(C(=O)N2CCN(c3cnccn3)CC2)cn1 +CCC(CC)c1nnc(NC(=O)c2ccc(N)nn2)s1 +Cc1nc(NCCNc2cccnc2)c2cccnc2n1 +CCCN(Cc1cccc(N)c1)C(=O)CC(F)(F)F +CC(C)C(c1cccs1)n1ncc(Cl)c1N +CCn1cc(C(=O)Oc2cccc(NC(=O)C3CC3)c2)cn1 +Cc1nc(-c2ccc(Cl)cc2)sc1CCNS(C)(=O)=O +CC(NC(=O)Cn1ccnc1)c1ccc(-c2ccccc2)cc1 +Nc1ccc(C(=O)Nc2ccc(Cl)cc2)c(Cl)c1 +CCOc1ccc(-c2cc3n(C)c(CN)cc(=O)n3n2)cc1 +N#Cc1ccc(-c2noc(-c3ccc(OCC(N)=O)cc3)n2)nc1 +Cn1c(C(=O)N2CC(c3ccccn3)C2)cc(=O)n(C)c1=O +Cc1csc2nnc(C(N)c3cccs3)n12 +O=C1c2ccccc2C(Nc2ccccc2)N1c1ccccn1 +CC1CCCCC1OCCNC(=O)c1nc2ccccc2c(=O)[nH]1 +COC(=O)c1cccc(OCc2noc(-c3ccnnc3)n2)c1 +Cc1ccc(S(C)(=O)=O)cc1NC(=O)NCCC(C)C +O=C(NCc1ccccc1)c1ccccc1OCCn1cccn1 +CCC(C)NC(=O)C1CCN(C(=O)OC(C)(C)C)C1 +O=C(NCc1ccccc1-n1ccnc1)N1CCc2ccccc2C1 +Cc1ccc(C(=O)Nc2ccc(Sc3cccs3)cn2)c(=O)[nH]1 +CNC(=O)Nc1ccccc1COc1ccc(CC#N)cc1 +CCCC(C)(C)NC(=O)CCn1nnc2ccccc2c1=O +Cn1ncc2c(NCCCn3cccn3)ncnc21 +COCC(=O)N1CCN(C(=O)C2CC3CCC2O3)CC1 +CCCn1c2c(c(=O)[nH]c1=O)C(c1ccccc1)C1=C(COC1=O)N2 +O=C(NCc1ccccn1)c1nc[nH]c1C(=O)NCc1cccnc1 +COc1cccc(NC(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)c1 +Cc1occc1CN(C)C(=O)Nc1ccc(OCC(F)(F)F)cc1 +NS(=O)(=O)c1ccc(NC(=O)NC(C2CC2)C2CC2)cc1 +CCN(CC)C(=O)COc1ccc(F)cc1Cl +COc1ccc(Cl)cc1C(=O)N1CCN(c2cnccn2)CC1 +Cc1ccc(SCC(=O)Nc2ccccc2C(=O)NC2CC2)cc1 +NC(=O)C1CCCCN1C(=O)CCCc1c[nH]c2ccccc12 +Cn1nccc1CCC(=O)N(c1cccc2cccnc12)C1CCC1 +CCC(CC)C(=O)NCC#Cc1ccc(NC(C)=O)cc1 +Cc1cccc2c1cnn2CCC(=O)NCCc1c[nH]c2ccccc12 +Nc1nc(Nc2ccc(Br)cc2)c2nc[nH]c2n1 +COc1ccccc1C(=O)NCC(C)(O)c1ccc(F)cc1F +O=C(Nc1ccc(F)cc1F)N1CCC(Nc2cccnc2)CC1 +COC(=O)NCC(=O)Nc1ccc(OC(C)C)cc1 +Cc1cc(NC(=O)c2ccccc2OCC(C)C)no1 +Cc1cccc(NC(C)C(=O)Nc2ccccc2C(N)=O)c1 +COc1cccc(NC(=O)CSc2cn(C)c3ccccc23)c1 +Cc1n[nH]cc1CNC(=O)c1cccnc1N(C)C +CCCNC(=O)c1nn(-c2cccc(C)c2)c(=O)n(CC)c1=O +O=C(NC1CCCN(c2ncccn2)C1)c1ccoc1 +COC(=O)Nc1cc(NC(=O)c2cc(OC)ccc2OC)ccc1F +Cc1ccc(-c2cc(CS(=O)(=O)NC3CCCNC3=O)on2)cc1 +O=C(c1ccc(-c2nc3ccccc3s2)o1)N1CCC1 +COC(=O)c1ccc(Cl)c(NC(=O)NCc2ccoc2)c1 +CC(=O)c1sc(-c2ccc3c(c2)OCO3)cc1N +CC(C)OCCCNC(=O)C1CCC(=O)N1C(C)C +CCN(C)C(=O)c1cccc(OC(=O)Cc2ccc(F)cc2F)c1 +Cc1ccc(-c2nc(C)c(C(=O)N(C)CC3CCCO3)s2)o1 +CC(Sc1nnc(N2CCOCC2)n1C1CC1)c1cccc(F)c1 +Cc1nc(C)n(CCCNC(=O)c2c3c(nn2C)CCCC3)n1 +CCCN(CCO)C(=O)Nc1ccc(F)cc1C +CC(C)(CNC(=O)Cn1ncc2ccccc21)c1cccs1 +Cc1nccn1-c1ncccc1NC(=O)c1cc(-c2ccccc2)[nH]n1 +CC(C(=O)NCc1ccc2c(c1)OCO2)n1ncn2cccc2c1=O +COc1cccc(NC(C)C(=O)Nc2nc(C)cs2)c1 +CCCc1cc(=O)oc2cc(OCC(=O)NC(C)C)ccc12 +COC(=O)CCCCNC(=O)Nc1cccc(Cl)c1F +Cc1ccc(F)c2c1CCCN2CC(=O)Nc1nccs1 +CC1CC(C)CN(C(=O)c2nc(N3CCOCC3)ncc2Cl)C1 +COc1ccc(CCC(=O)N(C)Cc2cc(C)on2)cc1F +CCSc1nnc(NC(=O)Cc2c(C)noc2C)s1 +CC(N(C)C(=O)c1ccc2[nH]cnc2c1)C(C)(C)C +Cc1ccc(CN2CCC3OCCC(C(=O)NC4CC4)C3C2)s1 +COC(=O)COc1ccc(-c2noc(C3CCCO3)n2)cc1 +O=C(Cc1ccc[nH]1)N1CCC(C(F)(F)F)CC1 +CCCNC(=O)c1ccc(NC(=O)NC(C)c2ccc(C)o2)cc1 +CN(CCc1ccc(O)cc1)C(=O)OC(C)(C)C +Cc1cc(C)cc(OCCN2CCC(C#N)CC2)c1 +CC(NC(=O)Nc1ccccn1)c1ccc(Br)cc1 +CNC(=O)c1cc(Cl)cn(Cc2ccc(C(F)(F)F)cc2)c1=O +Cc1c(NC(=O)Cc2ccc[nH]2)cccc1C(F)(F)F +Cc1cc2nc(C)c(CCC(=O)N3CCCCCC3)c(C)n2n1 +Cc1c(C(=O)N2CCCC2c2noc(C3CC3)n2)oc2ccccc12 +Cc1ccc(CC2CCCN(C(=O)c3csnn3)C2)cc1 +Cc1nc(C)c(C(=O)NCCSc2nnnn2C)s1 +CC(C)(C)NC(=O)CNC(=O)NCC(O)c1ccccc1Cl +CC1(C)CCC(C(=O)NCC(C)(O)c2ccc(F)cc2)CC1 +CCCCS(=O)(=O)Nc1cc(C)ccc1OC +COc1ccccc1CC(C)NCc1ccc(S(C)(=O)=O)c(C)c1 +O=C(C1CCC1)N(Cc1ccoc1)Cc1cccs1 +O=C(Nc1ccc(-n2cccn2)cc1)c1cccc(F)c1 +Cc1cc(C)n(CCNC(=O)Nc2ccc3c(c2)CC(C)O3)c(=O)n1 +CCCNC(=O)c1ccccc1NC(=O)c1cccc(F)c1 +Cc1ccccc1NC(=O)c1ccc2c(c1)NC(=O)C1CCCN21 +CCc1cc(C(=O)Nc2ccc(NC(=O)OC)cc2)[nH]n1 +CC(=O)c1cccc(NC(=O)c2cccc(-n3cccn3)n2)c1 +CCCC(=O)NC1CCCN(C(=O)c2cccc(OC)c2F)C1 +CC(C)(C#N)NC(=O)CC(c1ccccc1)c1ccccc1 +CCOCCOCC(=O)N1CCCN(C(=O)c2ccccc2)CC1 +CC1Oc2ccc(NC(=O)COc3cccc(F)c3)cc2NC1=O +COc1ccc(Cn2nnnc2SCC(F)(F)F)cc1 +Cc1ccc(OCc2nn3c(=O)c(C)nnc3s2)cc1C +FC(F)Oc1ccccc1CNc1cncnc1 +COCC(O)CN(C)C(=O)c1c(C)c2ccccc2[nH]c1=O +CCOC(=O)c1oc2cccc(Br)c2c1N +CC(C1CC1)N(CC(F)(F)F)C(=O)CSc1nccn1C +CCNC(=O)C1CC(c2ccc(OC)c(OC)c2)CN(C(C)=O)C1 +COc1ccc(F)cc1NC(=O)c1c(F)ccc(OC)c1F +Cc1cc(Cl)ccc1OC(=O)c1cc(C(N)=O)cs1 +CC(Nc1ccc2c(c1)C(=O)NC2)c1nnc(-c2ccccc2)o1 +CCCCN(CC(N)=O)c1ccc(F)cc1C(C)O +CC(C)C(C#N)NC(=O)c1ccc(-c2ccccc2)o1 +Cn1cccc1C(=O)NC1CC2C(=O)Nc3ccccc3C(=O)N2C1 +Cc1cccc(OCC(C)NC(=O)Nc2cnn(C)c2)c1 +O=c1[nH]c(N2CCCC2)nc2c1CCN(Cc1ccc(F)c(F)c1)C2 +NC(=O)c1ccc(NS(=O)(=O)c2ccc3c(c2)OCCO3)cc1 +Cn1ncc2c(N3CCC(NC(=O)c4ccoc4)CC3)ncnc21 +O=c1ccc(-c2nc(-c3ccccc3F)no2)c[nH]1 +O=S(=O)(NCc1ccc(Cl)cc1)c1cn[nH]c1 +CC(C)(C)OC1CCN(Cc2cnc(C3CCCC3)s2)CC1 +CCOc1ccc(F)c(C(=O)N2CC(C)CCC2C)c1F +CC(=O)Nc1ccccc1OCCn1cc(N)cn1 +CCN(c1ccccc1)S(=O)(=O)c1cccc(C(=O)NCCO)c1 +O=C(Nc1ccccc1-n1ccnc1)c1scnc1C1CC1 +COC(=O)c1ccc(S(=O)(=O)N(C)c2ccccn2)s1 +COc1cc(C)c(C(=O)CCC(=O)NC2CCCC2)cc1C +CC(NC(=O)CNC(c1ccc(F)cc1)C(C)(C)C)C(=O)N(C)C +COc1ccc(-c2nc3cc(-n4cnnn4)ccc3[nH]2)cc1C +CC(=O)NCCNC(=O)COc1ccc(C)c(C)c1 +O=S(=O)(NCc1cc(F)ccc1Br)c1cccnc1 +O=c1[nH]c2ncccc2cc1-c1c(F)cccc1Cl +CNc1nc2c(c(=O)n(C)c(=O)n2C)n1Cc1ccccc1 +CCN1CC(C(=O)Oc2ccc(F)cc2Br)CC1=O +CS(=O)(=O)c1ccc2[nH]c(=NC(=O)c3ccco3)sc2c1 +O=C(Nc1ccc(F)cc1Br)c1ccoc1 +Nc1cc(C(=O)OCc2ncccn2)c(Br)cc1F +Cc1cc2c(cc1CNC(=O)c1ccco1)OCCCO2 +O=C(CSc1nccc(=O)[nH]1)Nc1ccc(C(F)(F)F)cc1 +COc1ccc(CC(C)C(=O)Nc2c(OC)ncnc2N(C)C)cc1 +COc1ccc(CC(=O)Nc2cnn(C(C)(C)C)c2)cc1 +COc1ccc(O)c(C(=O)N(C)Cc2nccn2C(F)F)c1 +COc1ccc(C(=O)N2CCN(Cc3ccccc3OC)CC2)cc1 +COc1ccc(C)cc1NC(=O)CCn1ccc(C)n1 +CN(C(=O)CC(O)(c1ccccc1)C(F)(F)F)c1nccs1 +CC(C)CCCC1CN(C(=O)Cc2cccnc2)CCO1 +CC(C)N(C(=O)c1c[nH]c2cccc(F)c12)C1CCC1 +COc1cc(OC)cc(-c2nnc(NC(=O)Cc3ccccc3)o2)c1 +O=C(Nc1ccc2c(c1)C(=O)NCC2)c1ccc2ccccc2n1 +CC(C)(CNC(=O)Nc1ccc(OCC(N)=O)cc1)c1ccncc1 +O=C(NCCOc1ccc(Br)cc1)NCc1ccco1 +CCC(NC(=O)c1ccc(-n2ccnn2)cc1)c1noc(C)n1 +NC(=O)COc1ccc(CNc2ccc(F)cc2)cc1Cl +O=S(=O)(NCc1ccc(F)cc1)c1ccc2c(c1)CCC2 +Cc1cc(C)n(-c2ccc(C(=O)OCC(=O)Nc3ccccc3)cc2)n1 +Cc1nnc(NC(=O)CN2CCN(c3ccccc3F)CC2)s1 +CCN(CC)C(=O)c1cc2c(C)nn(C(C)(C)C)c2nc1N +Cc1ccccc1OCc1nc(C#N)c(N2CCCC2)o1 +CCc1nc(CN(C)S(=O)(=O)c2c(C)noc2C)no1 +Cc1cc(C)n2nc(CC(=O)NCCC(=O)NC3CCCC3)nc2n1 +C=CCn1c(C)nnc1SCC(=O)NCc1ccccc1 +Cc1ccc(-c2nc(CNc3nccnc3C#N)co2)cc1 +CCS(=O)(=O)N(C)CC(=O)Nc1cccc(OC)c1 +CC(C)c1ncc(C(=O)NC2CCC3CCCC32)cn1 +OCCn1ncc2c(N3CCCC3c3cccs3)ncnc21 +C#CCCOc1ccc(CN2CCC(CN3CCOCC3)C2)cc1 +CCc1cccc(CC)c1NC(=O)C(C)Oc1ccccc1N +Cc1cc(C)n2c(SCCc3ccncc3)nnc2n1 +CCOC(CC)C(=O)N1CCCC(NS(C)(=O)=O)C1 +CNc1nc(CNC(=O)Nc2cc(C(=O)OC)ccc2F)cs1 +CC(OC(=O)Cc1cccs1)C(=O)Nc1cccc2ncccc12 +COc1c(C)cnc(CNC(=O)Nc2cccc3cccnc23)c1C +Cc1cc(Cl)ccc1-n1nc(CC(C)C)nc1CN1CCCC1=O +Nc1cc(Cl)c(S(=O)(=O)N2CCCCCC2)c(Cl)c1 +CC(C)COc1ccccc1NC(=O)NCCO +O=C(c1cnc2ccccc2n1)N(CC(F)(F)F)C1CCOCC1 +CNS(=O)(=O)c1cc(C(=O)N2CCc3ccccc32)n(C)c1 +O=C1C(=O)N(Cc2cccc(F)c2)c2ccc(Br)cc21 +Cc1noc(C)c1CN(C)C(=O)C1CCN(C(=O)C2CCCC2)CC1 +NC(=O)C1CCN(C(=O)CCC(=O)c2ccc(F)c(F)c2)C1 +COc1cc2c(c(Cl)c1OC)C(CN(C)C)NCC2 +CCOC(=O)CCCNC(=O)Nc1ccccc1F +Cc1cc(C(=O)NCC2CCCO2)nc(N2CCOCC2)n1 +CC(Sc1nnc(-c2ccc(C(C)(C)C)cc2)o1)C(N)=O +CC(C)c1nc(CN(C)c2ncnc3[nH]ccc23)no1 +C=CCn1ccc2ccn(CCc3c(C)noc3C)c(=O)c21 +CCCC(C)N(C)C(=O)NC(CC(=O)N(C)C)c1ccccc1 +CCC1CN(C(=O)c2ccc(Cn3cncn3)cc2)CCO1 +CCOc1ccc(NC(=O)C2CC(=O)N(C(C)C)C2)cc1 +CCC(C(=O)N(C)C)N(c1cc(Cl)ccc1C)S(C)(=O)=O +CCOC1COC2(CCN(C(=O)c3ccsc3)CC2)C1 +Cc1nc(-c2nc[nH]n2)sc1C(=O)N(Cc1ccsc1)C1CC1 +COc1ccc(COc2cc(C)c(N)cn2)c(OC)c1 +CCC(NC(=O)c1ccc2ncsc2c1)c1ccc(OC)cc1 +NC(=O)c1csc(C(=O)Nc2c[nH]cc(Br)c2=O)c1 +CCn1cc(-c2nc3c4sc5nc(C)cc(C)c5c4ncn3n2)cn1 +Cc1cccc(C)c1OCCn1c(=O)oc2ccc(N)cc21 +COCc1ccc(C(=O)N=c2sccn2C)cc1 +Cc1occc1CNc1nccc2c1C(=O)OC2(C)C +CCc1ccc2nc(CC(=O)c3cccs3)[nH]c(=O)c2c1 +CC(=O)c1ccc(OCc2ccc(C(=O)N(C)CC3CC3)o2)cc1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1cccc(Cl)c1 +COc1cc(NC(=O)Cn2c(CO)nc3ccccc32)cc(OC)c1 +CC(=O)c1cc(CCC(=O)NCCc2ccc(Cl)cc2)oc1C +Cn1cnc(CNC(=O)NCCC(=O)Nc2ccccc2)n1 +CN(CCN1CCOCC1)C(=O)NC1CCc2ccccc2C1 +CCc1ccc(-c2c(-c3ccccc3)ncn2Cc2ncc[nH]2)o1 +Cc1nnc(N2CCC(OCCc3ccccc3)CC2)c(C#N)c1C +N#CCCN(CC1CC1)C(=O)CNC(=O)c1ccc(F)cc1F +Cc1cc(OC(F)F)c(C(=O)Nc2ccc(C#N)cn2)s1 +Nc1cc(C(=O)Nc2nc3c(s2)CCCC3)ccn1 +CC(C)NC(=O)CNC(=O)c1cccc(Br)c1 +COc1cccc(CNC(=O)CS(=O)(=O)c2ccc(C)cc2)c1 +Cc1nc(Nc2ncnc(Nc3ccc(Cl)cn3)c2N)sc1C +CCC(NC(=O)C1(O)CCCC1)C(=O)N1CCOCC1 +Cc1nc(CCNC(=O)NC2CCCCNC2=O)cs1 +COc1ccc(C(O)CNC(=O)Nc2nc(C)cs2)cc1 +Fc1cc2c(c(F)c1F)C(c1cc[nH]c1)NCC2 +COc1ccc(CC(=O)Cc2ccc(OC)cc2)cc1 +Cc1ccc2[nH]cc(NC(=O)N3CCOCC3)c(=O)c2c1 +CC(C)(Oc1cccc(Cl)c1)C(=O)Nc1ccc2c(c1)CC(=O)N2 +COc1ccc2cc(NC(=O)c3ccc(-n4cnnn4)cc3)cnc2c1 +COc1cccc(CNC(=O)Nc2cc(NC(C)=O)ccc2Cl)c1 +CSc1nc2ccccc2c(=O)n1CCCN1CCCC1=O +CCCOc1ccc(-c2ncc(C#N)s2)cc1OC +N#Cc1ccc(CNC(=O)NCc2ccc3c(c2)OCO3)cc1 +Nc1cnn(CCc2ccc(-c3ccccc3)cc2)c1 +CCCCSc1nnc(N2CCOCC2)n1CC1CCCO1 +COCC(C)OC(=O)C1(c2ccc(Br)cc2)CC1 +CCC1CN(S(=O)(=O)c2ccc(Br)cc2)CCO1 +CCOc1ccc(C(=O)Nc2cccc3ncccc23)cc1OCC +O=C(OCc1nnc(-c2ccccc2)o1)c1cc(=O)[nH]c2ccccc12 +Cc1cc(C)c(NS(=O)(=O)c2ccc(N)cc2)c(C)c1 +COc1ccc(C(C)=O)cc1CC(=O)N(C)C1CCCCC1 +COC(=O)C(C)Sc1nnc(NCC2CCCO2)s1 +O=C(COc1ccccc1Cl)Nc1nnc(-c2cccnc2)s1 +Cc1ccc(C(=O)N(C)C(C)c2nc3ccccc3s2)c(=O)[nH]1 +CC(C)(C)n1cc(NC(=O)Cn2ccccc2=O)cn1 +COC(=O)Cn1cnc2onc(-c3cccc(F)c3)c2c1=O +CC(=O)NCCNC(C)C(=O)c1ccc2c(c1)NCC(C)O2 +C=CCCCN(C)C(=O)Nc1ccc(NC(C)=O)c(OC)c1 +Cc1ccccc1OCCNC(=O)CSc1ncn[nH]1 +Cc1ccc(-c2csc(NCC(C)C)n2)c(=O)[nH]1 +Cc1ccc(N2CCc3onc(-c4ccccc4F)c3C2)nn1 +CN(C)C(=O)CNC(=O)c1sccc1Br +CCOc1ccc(C(=O)N2CCN(C(=O)C3CCCO3)CC2)nn1 +CSc1ncccc1C(=O)Nc1cc(F)ccc1F +CC1CCc2ccccc2N1C(=O)Cn1c(=O)n(C)c2ccccc21 +Cc1ccc2c(=O)c3cc4[nH]c5cc(C)ccc5c(=O)c4cc3[nH]c2c1 +O=C(c1csc(C2CC2)n1)N1CCC(Nc2cccnn2)CC1 +O=C(c1ccccc1Cl)N1CCCC(CO)C1 +Cn1c(C2CC2)nc2cc(NC(=O)CCCCNC(N)=O)ccc21 +COc1c[nH]c(C(=O)N2CCC(OCc3ccccc3)CC2)cc1=O +N#Cc1ccc(N2CCN(c3ccc4nncn4n3)CC2)nc1 +Cc1ccn(CC(=O)Nc2cc(-c3ccncc3)n[nH]2)n1 +CCCn1nnnc1SCC(=O)N1C(C)CCCC1C +CC(C)c1ccc(CCN2CCCS2(=O)=O)cc1 +COc1cccc(CC(=O)NCC(OC)c2ccsc2)c1 +CCn1nc(C)c(CNC(=O)c2cccc(C#N)c2)c1C +CC(NC(=O)N(Cc1cccs1)CC1CCCO1)c1nncn1C +COc1cc(C(=O)N2CCC3(CCCN(CCO)C3=O)C2)ccn1 +CC(=O)N1CCC(Cc2nc3cccnc3n2C)C1 +Cc1c(Cl)ccnc1CS(=O)(=O)c1nc2ccccc2[nH]1 +Fc1cccc(F)c1CNc1cccc2[nH]ncc12 +CC(C)(CNC(=O)NCC1COc2ccccc2O1)N1CCOCC1 +CC(C)c1nnc2n1CCN(C(=O)CC1CCCCC1)C2 +CCCCN(C)C(=O)c1ccn2c(-c3ccccc3)nnc2c1 +O=C(Cc1ccc(Cl)cc1)Nc1cccc(O)c1 +CC(NC(=O)c1cc(C(F)(F)F)ccc1F)c1ncon1 +CCCn1nc(-c2cc(C)c(OC)c(C)c2)cc(C#N)c1=O +Cn1nc(C(C)(C)C)cc1C(=O)N=c1[nH]c2ccccc2[nH]1 +CCNC(=O)c1ccc(NC(=O)N2CCC(C)CC2)cc1 +Cn1nc(C2CCN(C(=O)c3ccc(=O)[nH]c3)CC2)n(C2CC2)c1=O +CCCc1cc2c(=O)c(-c3ccon3)coc2cc1OC +CNC(=O)NC(C)(C)C(=O)N(C)Cc1ccsc1 +CC(c1ccccc1)C(CO)NS(=O)(=O)N1CCCCCC1 +Cc1cccc(C)c1NC(=O)CNCc1ccc(-n2cncn2)cc1 +CC(O)CN1CCN(C(=O)c2cc(Cl)ccc2OC(C)C)CC1 +COCCn1c(C)c(C(=O)OC)c2cc(O)c3ccccc3c21 +CC(=O)NC(CC(=O)Nc1ccccn1)c1cccs1 +COc1cccc(NC(=O)NCc2cnn(C)c2)c1 +O=C(Nc1ccccn1)C1CCCN(c2ccc3nnnn3n2)C1 +Cc1nccn1-c1ccc(CNC(=O)CC2CCCC2)cc1F +COc1cc2c(cc1OC)C(Cc1cccs1)=NCC2 +Cc1ccc2c(C)c(C(=O)Nc3nnc(C)s3)oc2c1 +CC(=O)NC(C)C(=O)NCC1(c2ccccc2Br)CC1 +COc1ccc(C(=O)Nc2ccc(N3CCNC3=O)cc2)cc1 +OC(COCc1ccccc1F)Cn1cc(Br)cn1 +CC(NC(=O)C1CC(=O)N(Cc2ccco2)C1)c1ccccc1Cl +CC(c1ccc(Cl)cc1)N(C)C(=O)NCCN1CCOCC1 +CCC1c2ccsc2CCN1C(=O)c1cscn1 +NS(=O)(=O)CCNC(=O)c1cc2ccc(Cl)cc2[nH]1 +Fc1ccc(N2CCC3(CC2)CC(Oc2cccnc2)CO3)cc1 +O=C(OCC(=O)N1CCc2ccccc21)c1ccccc1Cl +O=C(Cc1ccc(F)cc1F)N1CCOc2ncccc21 +CCc1ccc(C(=O)NCc2nnc(SC)n2CC)cc1 +O=C(Nc1cccc2c1CCCC2)N1CCC(CN2CCOCC2)C1 +Cn1nc2nnc(-c3ccc(F)cc3)c(-c3ccc(F)cc3)n2c1=O +Fc1ccc(NCc2c(F)cc(F)cc2F)nc1 +Cc1ccc(OCC(=O)OCC2CCCO2)cc1 +COc1ccnc(N2CCC(C(=O)NCCc3cnn(C)c3)CC2)n1 +O=C(NCc1cccc(-n2cccn2)c1)NC1CCC(O)CC1 +CCCCn1nnnc1COc1ccc2c(c1)CCC2 +CC1CN(CC2CCCN2C(=O)CCn2cncn2)CC(C)O1 +O=C(Oc1ccc(-n2cnnn2)cc1)c1cc(-c2ccccc2)on1 +CCNS(=O)(=O)c1ccccc1NC(C)C(C)C +CN(CC(O)C1CC1)C(=O)c1ccc2ccccc2c1O +CCNC(=O)N1CCN(CC(=O)NCC2CC2)CC1 +CCCOC(=O)C(C)N1CC(C)Oc2ccc(C(C)=O)cc21 +Cc1cccc(C(=O)Nc2ccc(NCCO)nc2)c1 +CSc1cccc(NC(=O)C(C)NC(=O)c2ccoc2)c1 +CNC(=O)CN(c1cc(C)ccc1C)S(=O)(=O)c1ccccc1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)N(C)C(C)CC#N +COCCOc1ccc(CNc2cc(N)nc(C)n2)cc1 +CC(NC(=O)C1COc2ccccc21)c1cccc(N2CCCC2)c1 +Cc1ccccc1-n1nc(C)c2[nH]c(-c3nc(C)c(C)nc3C)nc21 +O=C(CNC(=O)c1ccc(F)cc1)Nc1cccc2cccnc12 +COc1ccc(Cc2c[nH]c(=O)nc2N)cc1OC +O=C(NC1CC1)c1cnn2c1CN(Cc1ccc(F)cc1)CC2 +O=C(CSc1nncc2ccccc12)NCCc1ccc(F)cc1 +O=C(Nc1ccc(F)cc1Cl)c1cc2ccccn2n1 +CC(C)c1ccc(S(=O)(=O)NCCCO)cc1 +COCC(C)NC(=O)CSc1nnc(C(C)(C)C)n1N +COCc1ccccc1CNC(=O)N1CCCCC1C +O=S(=O)(c1cccnc1)N(Cc1ccc(F)c(F)c1)C1CC1 +COC(C)(C)c1noc(CCCNC(=O)C(C)(C)C)n1 +CNC(=O)c1nnn(-c2cccc(Br)c2)c1C(F)(F)F +Cc1ccc(N2CC(C(=O)Nc3ccc(Cl)cn3)CC2=O)cc1C +NC(=O)C1(CNC(=O)COc2ccc(Cl)cc2)CCOCC1 +O=C(NCC1(c2ccccc2)CCOCC1)C1CC1 +COc1ccc(C)cc1NC(=O)CCCC(=O)N(C)C +CC(NC(=O)c1cnc2ccccc2n1)c1ccc2c(c1)OCO2 +COCC12COCC1CN(C(=O)c1ccnc3ccccc13)C2 +Cc1ccccc1NC(=O)Cc1nc2ccc(Cl)cc2c(=O)[nH]1 +O=C(CCSc1ccccn1)NCc1nnc2ccccn12 +O=C(NC1CCCc2occc21)c1ccc(N2CCNC2=O)cc1 +Cc1nnc2n1CCN(C(=O)CCn1ccc3ccccc31)C2 +COc1ccccc1C(=O)NCC(O)c1ccc(F)c(F)c1 +COc1cccc(NC(=O)c2cc(OC)cc(OC)c2)c1 +CN(C(=O)Cc1ccc(N2CCCC2=O)cc1)c1ccccc1 +O=C(CCC(O)c1ccc2c(c1)OCCCO2)N1CCCC1 +O=C(Cc1ccc(O)cc1)N1CCN(Cc2ccccc2CO)CC1 +CC(C)Cn1nccc1NC(=O)CCc1ccccc1F +CCN(CC1CCOC1)C(=O)c1ccccc1N1CCOCC1 +COCC(O)CN(C)C(=O)c1cc(N)ccc1F +CCC1Oc2c(SC)nc(C)nc2N(C)C1=O +COc1cc(NC(=O)c2scnc2C)ccc1N1CCOC1=O +COc1cccc(C(=O)NCc2c[nH]nc2C)c1OC +CCOc1ccccc1NC(=O)c1ccc(NS(C)(=O)=O)cc1 +COC(=O)c1ccccc1NCc1nc(C(C)C)no1 +O=C(NCc1nncn1-c1ccccc1)NCC1CCC1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1cc(Cl)ccn1 +Cc1ccccc1CC(=O)Nc1cc(C(=O)N(C)C)ccc1Cl +Cc1cc(C(O)C(=O)Nc2ccccc2C#N)ccc1F +O=C(NCCn1c(-c2cccnc2)noc1=O)OCC(F)(F)F +COc1cc(C)ccc1NC(=O)N(C)C(C)CC#N +Cc1oc(S(N)(=O)=O)cc1C(=O)Nc1ccc(Cl)cc1F +CCS(=O)(=O)N(C)CCOc1ccccc1C +COc1cc(C)c(S(=O)(=O)Nc2ccccc2Cl)cc1OC +COc1ccc(Cl)c2c1CCNC2c1nccs1 +CCS(=O)(=O)N(C)c1ccc(C(=O)Nc2ccccc2C)cc1 +O=C(Nc1cccc(-n2cccn2)c1)NC(CCO)c1ccccc1 +C=C(C)Cn1nnc(CO)c1COc1ccccc1 +COc1ccc(SCCS(=O)(=O)c2ccccc2)cc1 +Cc1ccn2c(=NC(=O)c3c(F)cccc3Cl)[nH]nc2c1 +CCN1C(=O)c2oc3cc(C)c(C)cc3c(=O)c2C1c1ccncc1 +O=C1CSc2ccccc2N1CC1COCCO1 +COc1ccc2c(=O)c(NC(=O)NCCCn3ccnc3)c[nH]c2c1 +Cc1ccc(CNC(=O)Cc2n[nH]c3ccccc23)n1C +COc1ccc(C)nc1NC(=O)NCc1nc(C(F)(F)F)cs1 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)NCCCn1cccn1 +N#CCc1ccc(OS(=O)(=O)c2ccccc2Cl)cc1 +O=C(NCC1NCCc2ccccc21)OCc1ccccc1 +CC(C)Cn1nccc1NC(=O)CSc1nnnn1C1CCCC1 +CCOC(=O)N1CCN(C(=O)C(C)CC(N)=O)CC1 +CCCN(CC(=O)NC)C(=O)CC1(O)CCCCC1 +CCCCCC(C)NC(=O)c1cccc(S(C)(=O)=O)c1 +COc1ccc2nc(SCc3noc(C(C)C)n3)[nH]c2c1 +O=C(CNC(=O)C1CC1)c1ccc2c(c1)OCCCO2 +NC(=O)c1ccc(Cl)cc1NCC(=O)N1CCc2sccc2C1 +CCCOCc1ccccc1CNc1nccn2cnnc12 +COCCNC(=O)NC1(C(F)(F)F)Oc2ccccc2O1 +Cc1cnc(C(=O)N2CCN(C(=O)C3CCCO3)CC2)cn1 +NC(=O)c1ccsc1NC(=O)c1cccc(Oc2ccccc2)c1 +CCc1ccccc1NC(=O)C1NC(=O)CC1c1ccccc1 +Cn1cc(CCC(=O)N2CCCc3cc(F)cc(F)c32)cn1 +CCOC(=O)Cc1csc(-c2cccc(N)c2)n1 +CC(C)NC(=O)c1nc(-c2ccccc2)n(-c2ccc(Cl)cc2)n1 +COc1ccc(F)c(NCc2cnc(C3CC3)s2)c1 +COc1ccc2c(ccn2CCNC(=O)C2CCC2)c1 +Cn1cccc1C(=O)N1CCc2c(CNc3nccs3)n[nH]c2C1 +COC(=O)N1CCN(C(=O)Nc2cc(C)c(F)cc2Cl)CC1 +COc1ccccc1CNC(=O)c1ccccc1SC(F)F +Cc1cnc(C(=O)N2CCCN(C(=O)c3ccccc3F)CC2)cn1 +NC(=O)c1ccc(CN2CCCC(c3noc(C4CC4)n3)C2)cc1 +CC(NC(=O)c1ccoc1)C(=O)Oc1ccc(C#N)cc1Cl +COCCN1CCN(C(=O)C(C)Cc2c(C)n[nH]c2C)CC1=O +Cc1sc2ncnc(N3CCN(C(=O)c4nc[nH]n4)CC3)c2c1C +Cc1nnc(CN(C)CC(=O)Nc2nc(-c3ccco3)cs2)n1C +CCNC(=O)C1(NC(=O)c2ccc3nnc(C)n3c2)CCCCC1 +C=CCNC(=O)c1ccc(NC(=O)N2CCCC2CO)cc1 +CNc1ccc2ccnc(OCC(F)(F)F)c2c1 +CCCNC(=O)c1ccc(NC(=O)CNC(N)=O)cc1 +COC(=O)c1cc(C)nc2c1c(C1CC1)nn2-c1ccc(F)cc1 +CCC(NCCc1nc(C)cs1)c1ccc(O)cc1 +Cc1ccn2cc(C(=O)N(C)CCCc3nc4ccccc4[nH]3)nc2c1 +O=C(CCSc1ccccn1)N1CCN(c2ccccc2)CC1 +Cc1cc(C)n(CCN2CCN(C(=O)CC(C)(C)C)CC2)n1 +CCN(Cc1ccc(OC)c(OC)c1)C(=O)C(C)c1cccs1 +Cc1nc(C(N)c2ccc(F)c(F)c2)sc1C +NC(=O)c1cccc(C(=O)Nc2ccc(N3CCOCC3)cn2)c1 +CC(C)C(C)(C#N)NC(=O)CNC(C)(C)c1ccccc1 +Nc1cc(Cl)ccc1SCc1ccccn1 +COc1ccc(CNC(=O)C(C)Sc2nccn2C)cc1OC +CCC1Oc2c(N)c(Cl)cc(Cl)c2N(C)C1=O +N#CCOc1cccc(CC(=O)NC(c2nccs2)C2CC2)c1 +CNC(=O)C1CCCN(C(=O)Nc2cnn(Cc3ccccc3)c2)C1 +Cc1n[nH]c(C)c1NC(=O)Nc1ccccc1C(=O)N1CCOCC1 +Cc1ccc(C(=O)OCCN2CCOC2=O)cc1C +Cc1cc(Oc2ccccc2C)nc(C2CCN(C(=O)C3CC3)C2)n1 +O=C(NCCCOCC1CC1)NC1CCCCCC1 +CN1CC(NC(=O)NCCCc2ccccc2)CC1=O +COCC(C)NC(=O)C1CCN(c2ccc3nncn3n2)CC1 +Cc1ccc(NC(=O)Cn2nc(C(F)(F)F)cc2C2CC2)cc1 +CCn1cnnc1CNC(=O)Nc1ccnn1Cc1ccc(F)cc1 +Cc1n[nH]cc1CN1CC(c2ccccc2Cl)OCC1(C)C +C=CCn1c(C)nnc1SCCOc1ccc(Cl)cc1 +Cc1cccc(C)c1NC(=O)CCc1ccccc1F +O=C1Nc2c(cc(Cl)c(Cl)c2Cl)C1=O +COc1cc(S(=O)(=O)n2cc(C)nc2-c2ccccc2)ccc1F +CS(=O)(=O)N1CCc2cc(C(=O)N3CCCCCC3)ccc21 +Cc1ccc2cc3c(nc2c1)OC(=O)N(C1CC1)C3 +CCS(=O)(=O)N(C)CC(=O)N(C)Cc1ccc(F)cc1Cl +Cc1ccc(C(=O)NCc2cn3cccc(C)c3n2)cc1 +Cc1cc(NC(=O)C(C)Oc2cc(Cl)ccc2Cl)no1 +COc1ccccc1CCC(=O)NCC1C(=O)N=C(C)C=C1C +O=C(COc1ccc2ccccc2c1)N1CC(c2nc(C3CC3)no2)C1 +CC(C)N(CCC#N)C(=O)c1ccc(F)c(F)c1 +COC(=O)c1ccc(-c2csc(NC(=O)c3ccccn3)n2)cc1 +Cc1cc(C(=O)Nc2nnc3n2CCCC3)n(C)n1 +Cc1cc(C(=O)N(C)C(C)c2ccccc2F)on1 +COc1ccc(NC(=O)N2CCc3cc(F)ccc3C2)cc1F +CC1(CNC(=O)c2ccnc(OC3CCC3)c2)CCC1 +NC(=O)c1csc(CN2CCC(Nc3ccccc3)C2)c1 +Cc1cnn(CC2CCCCN2C(=O)COc2ccc(C#N)cc2)c1 +CN(Cc1ccc(F)c(F)c1)C(=O)c1ccc(-n2ccnn2)cc1 +Cc1occc1C(=O)OCC(=O)N1c2ccccc2NC(=O)CC1C +Cc1cc2nc(-c3ccc(N)cc3O)oc2cc1C +O=C1CCCN1CCCC(=O)N1CCC(Oc2cccc(F)c2)CC1 +CN(CC(=O)Nc1ccccc1C(N)=O)c1cccc2ccccc12 +CCc1ccc2occ(CC(=O)NCc3ccccn3)c2c1 +COc1cc(Cn2cnc(C#N)n2)ccc1SC +Cc1ccc2c(c1)C(=O)C(=O)N2CCSc1cccc2cccnc12 +CCC(OC)C(=O)NCc1cc(OC)c(O)c(OC)c1 +Cc1cccc(S(=O)(=O)Nc2ccc3c(c2)CC(=O)N3C)c1 +CCC(C)C(=O)Nc1cccc(CNc2cccc(C(=O)NC)n2)c1 +CCC1(CC)CC1C(=O)N1CCC(n2cc(C(C)(C)O)nn2)CC1 +COc1cc(C2NCCc3c(Cl)cc(F)cc32)ccn1 +CCc1nc(C#N)cc2cc(OC)c(OC)c(OC)c12 +CCc1cc2c(=O)n(CC#N)c(-c3ccncc3)nc2s1 +CC(C)n1ccnc1CN1CCCN(C(=O)CC2CCCO2)CC1 +Cc1nc2ccccc2nc1CSc1nccn1C +COCc1ccccc1NC(=O)CCc1cccs1 +COc1ccc(C(=O)n2nc(C)c3c2CC2C3C2(C)C)c(OC)n1 +Cc1ccccc1OCC(=O)NCC(O)C1CCCCC1 +CCOc1ccc(NC(=O)NCc2ccncc2CC)c(C)c1 +c1ccc(-n2ccnc2)c(NCc2cncnc2)c1 +CC(=O)C(C)(C)c1ccc2c(c1)NC(=O)C(C)S2 +C=CCN(Cc1ccccc1F)S(=O)(=O)c1cccc(C#N)c1 +Cc1cc(C)nc(SCC(=O)Nc2ccnn2C(C)C)n1 +COCCN(Cc1cnn(C)c1)C(=O)Cc1sc(C)nc1C +CCC(C)NC(=O)N1CCN(C(=O)c2nsc3ccccc23)CC1 +Cc1ccc(C(=O)NC(C(=O)OCC(F)(F)F)C(C)C)cc1 +Cc1noc(C)c1C(=O)N1CCCC(CNC(=O)OC(C)(C)C)C1 +Cc1cnc(C(=O)Nc2nc3cc4c(cc3s2)OCCCO4)cn1 +Cc1cc(=O)n(CC(=O)N2CC3C4CCC(CC4)C3C2)nc1C +COc1cc(C)c(Cl)c(C)c1-c1csc2nc(N)nn12 +Cc1cc(NC(=O)C(c2ccccc2)N2CCOC(C(N)=O)C2)no1 +CCOCc1ncn2c1CN(C(=O)c1occc1C)CC2 +Cc1cccc(NCC(=O)N2CCc3ccccc3C2)c1C +CC(O)CNC(=O)C1(C)Oc2ccccc2NC1=O +CC(C)COCCNC(=O)N(C)Cc1ccc(F)cc1 +CCC(CC)(CO)Nc1nn(C)c(=O)n(C)c1=O +COC(=O)c1ccoc1Cn1c(C(F)(F)F)ccc(C(N)=O)c1=O +CCc1ccc(N(C(C)C(=O)N2CCOCC2)S(C)(=O)=O)cc1 +COC(=O)c1ccsc1NC(=O)c1cc(-c2ccc(C)cc2)no1 +COC(=O)C1(NC(=O)c2occc2C)CCCC1 +COC(=O)N1CCC(CNC(=O)NCCc2ccc(OC)cc2)CC1 +CCC(=O)N1CCCC1C(=O)c1cc(OC)ccc1OC +CCn1nccc1CN(C)C(=O)c1ccc(Cn2nc(C)cc2C)o1 +CC(c1ccon1)N(C)S(=O)(=O)NCc1ccccc1 +CCn1c(CNc2ccc(C)c(Cl)c2)nnc1SCC(N)=O +Cc1nc2nc(-c3ccc(F)cc3F)cn2nc1C +O=C(NCCc1ccccc1)N1CCC2CNS(=O)(=O)C2CC1 +Cc1ccc(-c2nc3nc4c(cn3n2)C(=O)CCC4)cc1 +CNC(=O)COc1ccccc1CNc1ccc2oc(C)nc2c1 +O=C(CSc1nc2ccccc2[nH]1)Nc1ccccc1 +CC(C)c1nccc(C(=O)N(C)CC2CCCCO2)n1 +COCc1cccc(NC(=O)c2ccccc2Cl)c1 +COCCC1(CO)CCCN(C(=O)c2csc(C)n2)C1 +CC(=O)N(CCCNC(=O)c1ccccc1Br)C(C)C +CC(C)N1C(=O)C(C)(C(=O)NC2CCCCC2)Oc2cccnc21 +Cc1ncsc1C(=O)NCc1cccnc1OCC(F)(F)F +O=C(Nc1ccc(CN2CCOCC2)cc1)c1cc2ccccc2[nH]1 +O=C(c1ccco1)N1CCOC2(CCN(c3ncccn3)CC2)C1 +C=CCN(Cc1cccc(OCC)c1)C(=O)c1ccon1 +CCOC1CCCN(C(=O)c2cn(-c3ccccc3)nn2)C1 +O=S(=O)(NCC1(c2cccc(F)c2)CCOCC1)c1ccccc1 +CSc1cccc(NC(=O)CCCc2nnc3ccccn23)c1 +Cc1cnc2c(S(=O)(=O)NCCN3CCOCC3)cccc2c1 +CCS(=O)(=O)NCCC(=O)Nc1cccc(C)n1 +Cc1ccsc1CN1CCN(c2cccs2)CC1 +CNC(=O)CNS(=O)(=O)c1sccc1Br +COc1nn(C)cc1C(=O)NCc1cc(-c2cccs2)n(C)n1 +CCC(=O)Nc1ccc(C)c(OCc2cc(=O)n3oc(C)cc3n2)c1 +Cc1cccc(C(N)=O)c1NCc1cc(C#N)ccc1F +CC(C)c1ccc(S(=O)(=O)NCC(C)(C)NS(C)(=O)=O)cc1 +CCOc1nnc(CN2CCCC(c3cc(C)[nH]n3)C2)s1 +Cc1nnc(NC(=O)c2cc(-c3ccccc3O)n[nH]2)s1 +COC(=O)CSc1nnc(N2CCCC2)n1-c1ccc(C)cc1 +O=C(Cn1cncn1)Nc1ccccc1Br +COc1ccc(C(=O)OCC(=O)NCC2CCCO2)c(O)c1 +Cc1nnnn1-c1cccc(NCC(=O)N2CC(C)OC(C)C2)c1 +CCSc1nc2n(n1)C(c1sccc1C)C(C(N)=O)=C(C)N2 +CC1CCCCC1NC(=O)CNC(=O)c1ccco1 +CC(C)=CC(=O)Oc1cccc(NC(=O)CN2CCCC2=O)c1 +O=C(NCc1cccc(F)c1)c1[nH]cc2c1CCC2 +Cc1nc2ccccc2n1CCNC(=O)c1scnc1C1CC1 +COc1cccc(-c2cc(C3(C(=O)NC(C)(C)CO)CC3)no2)c1 +Cn1cnnc1SCc1cn2cc(Cl)ccc2n1 +O=C(NCc1ccccn1)c1cnc2ccsc2c1 +Nc1cc(Cl)ccc1NC(=O)c1ccc(F)cc1 +COc1ccccc1CC(C)N(C)c1ccc2nccnc2n1 +COc1ccc(-c2n[nH]c(CC(C)C)c2NC(C)=O)cc1OC +O=S(=O)(c1ccc(Br)cc1)n1cnc2ccccc21 +CCOC1CCN(C(=O)Cc2ccccc2F)C2CCOC12 +Cc1noc(CCNC(=O)N2CCCCCC2c2c(C)n[nH]c2C)n1 +CC(C)CN1CCOC(CNC(=O)c2cnn(-c3ccccc3)n2)C1 +CN(CC(O)C1CC1)C(=O)c1cccc(NC(=O)C2CCCO2)c1 +COc1cccc(NC(=O)N2CCC3(CC2)OCCCO3)c1OC +COC(=O)c1cnc(NC(=O)CCc2ccco2)s1 +C#CC(CC)(CC)NC(=O)Cn1c(=O)c(C#N)cn(C)c1=O +CN1CCCN(Cc2n[nH]c(=O)[nH]2)c2cc(Cl)ccc21 +COc1ccc2c(c1)[nH]c1c(=O)n(CCO)cnc12 +CC(=O)NCC1CCCN(C(=O)NCCc2ccc(C)cc2C)C1 +CCN(CCO)C(=O)Cc1coc2cc(OC)ccc12 +COCCOC(=O)C1=C(C)NC(=O)NC1c1cc(C)ccc1C +COCCCNC(=O)C1CC(=O)N(c2ccc(C(C)C)cc2)C1 +CC1CCCCC1CNC(=O)C(O)C(O)c1nc2ccccc2s1 +COc1ccc2c(c1)OCC(CNC(=O)Cc1sc(C)nc1C)C2 +CCOc1ccc(NC(=O)NC2C=CC(CO)C2)cc1C +O=C(Nc1ccc(-n2cncn2)c(F)c1)c1ccc(Cl)cc1F +Cc1ccc(C)c(-n2ccnc2SCC(=O)NC(C)CO)c1 +CNC(=O)c1cccc(OC(=O)Cc2ccc(C)s2)c1 +CC(=O)N1CCCN(C(=O)c2cc3ccc(C)cc3[nH]2)CC1 +Cc1cc(C(=O)NCc2nnc3n2CCCC3)[nH]n1 +CCC1CCCCN1C(=O)c1cccc(-n2cccn2)n1 +CCC1CCC(CNC(=O)c2sc(C)nc2C)CC1 +NC(=O)COc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1 +Cc1cc(-n2cc(C(=O)NCCc3cccs3)nn2)ccc1F +CN(CCC(=O)N1CCOCC1)Cc1nc2ccccc2n1C +COCc1cccc(C(=O)NCCOc2ccc3c(c2)OCO3)c1 +c1cc(-n2cnnc2)cc(-n2cnc3ccccc32)c1 +COCCn1c(-c2ccc(C)cc2)ccc(CO)c1=O +COc1ccc(N)cc1OCC(=O)Nc1cccc(C)c1 +Cc1cnc(NC(=O)c2ccc(C(=O)N(C)C)cc2)s1 +O=C(C1CCC1)N(Cc1cccnc1)c1ccc(Cl)cc1 +COc1ccc(F)cc1NC(=O)Cc1noc2ccccc12 +c1ccc2c(c1)CCCN2c1ncnc2n[nH]cc12 +COCC(NC(=O)c1cc(SC)ccc1C)C(N)=O +Cc1ccc(-c2nc(CNC(=O)c3csc(C(C)C)n3)no2)cc1 +CCCN(CCC)C(=O)c1cc(OC)cc(OC)c1 +CCCn1cc(C(=O)NCCCC(N)=O)c2ccccc21 +CC(=O)N1CCC(C(=O)NCCc2ccc(OC(F)F)cc2)CC1 +Cc1cc(C(=O)OC(C)C(=O)NCc2ccccc2)c2ccccc2n1 +COc1ccc(O)c(C(=O)Nc2ccc3[nH]c(C(F)F)nc3c2)c1 +Cc1oc(-c2ccccc2)nc1CNc1cccc(Cn2cnnc2)c1 +CC(C)COC1CCN(C(=O)C2CC2c2ccccc2F)CC1 +C#CCN1CCN(C(=O)NCc2ccc(OCC)c(OC)c2)CC1 +O=C(Nc1cccc(-c2nnco2)c1)N1CCC12CCC2 +COCCNC(=O)N1CCN(c2ncccc2C#N)CC1 +CC(=O)Nc1ccc(NC(=O)c2ccccc2C)c(OC(C)=O)c1 +N#Cc1cccc(-c2csc(-c3cccnc3)n2)c1 +O=C(Cc1cccs1)NCc1ccnc(-n2cccn2)c1 +CCN(CC)C(=O)Nc1cc(NC(C)=O)ccc1C +Cc1[nH]nc2c1NC(c1nc(-c3ccccc3)cs1)NC2=O +CCc1noc(CC)c1CC(=O)NCc1csc(N(C)C)n1 +Cc1nnc(SCC(=O)N(C(C)C)C2CCCC2)n1N +COc1ccc(C)cc1CCNC(=O)C1Cc2ccccc2C(=O)O1 +Cn1cc2c(NCC3(c4ccc(F)cc4Cl)CC3)ncnc2n1 +CC(OCC(F)(F)F)C(=O)NCCc1ccccn1 +CC(=O)N(Cc1cc2ccc(C)cc2[nH]c1=O)c1ccc(C)cc1 +N#Cc1cccc(OCc2ccoc2C(=O)N2CCCCCC2)c1 +CC(C)CN1CC(C(=O)NCCNC(=O)c2ccccc2F)CC1=O +CC1CC(=O)c2cc(C(=O)N3CCOCC3)c(=O)[nH]c2C1 +CCCNc1nc(-c2ccccc2)c(C#N)c(N)c1C#N +CC(C)(C)NC(=O)CNC(=O)C1CCCc2ccccc21 +O=C(NCC1OCCc2cn(CC3CC3)nc21)c1ccnnc1 +Cc1cccc(NC(=O)c2sc(-c3ccccn3)nc2C)c1 +Cc1cnc(C(=O)NC(CC(F)(F)F)c2ccc(F)cc2)cn1 +CC(=O)Nc1ccc(NC(=O)c2cnc(C3CCCO3)s2)cc1 +COc1cccc(C(=O)Nc2ccccc2O)c1O +CCc1nnc(C(C)Sc2nnc(NC3CCCCC3)s2)o1 +CCc1ccc(N2CCN(C(=O)c3ccco3)CC2)cc1N +N#Cc1ccc(CN2CC3CCC(C2)N(Cc2ccccn2)C3=O)cc1 +COc1ccc(CNC(=O)COc2ccc(Cl)cc2)cc1 +COc1cccc(CNC(=O)CCn2ncc3c(Cl)cccc32)c1 +COc1cccc(C(=O)NC2(C(=O)NCC(C)C)CCCC2)c1F +CC(C)(O)C(=O)NC1CCCc2nc(N3CCC(CO)CC3)ncc21 +Cc1cc(Cl)ccc1NC(=O)c1cscn1 +Cc1ccccc1-n1c(C)nnc1SC(C)C(=O)NC1CC1 +CCCn1c(-n2nc(CC)cc2CC)nc2c1c(=O)[nH]c(=O)n2C +O=C(COC(=O)c1ccc(F)cc1)Nc1ccc(F)c(F)c1F +CC(OC(=O)c1nccnc1N)C(=O)Nc1ccccc1C#N +CC(C)(C)C(=O)N1CCC(NS(C)(=O)=O)CC1 +CC(=O)Oc1ccc(C2NCCc3ccc(F)cc32)cc1 +C=CCOc1ccc(CN2CCOCC2CC)cc1OC +Cc1nc(-c2noc3ccc(C(=O)NCCO)cc23)cs1 +CCOc1ccc(NC(=O)NCc2nc3ccccc3s2)cc1 +CCCCc1nc2cc(C(=O)N3CCCCC3COC)ccc2o1 +O=C(NCCCn1cccn1)Nc1cccc(Cl)c1-n1cccn1 +O=C1CCCCCN1CCCNc1ncccc1C(F)(F)F +O=S(=O)(NC1CCCc2ccccc21)c1cccc2nonc12 +C#CCOc1cc(F)ccc1NCc1noc(C(C)C)n1 +CC(NC(=O)N(C)Cc1nnc2n1CCC2)c1ccccc1F +COc1ccccc1C(C)NC(=O)c1cccs1 +CN(C)c1ccccc1NC(=O)Cn1ccc(=O)[nH]c1=O +CC(=O)N1CCN(CC(=O)NCCc2ccc(F)cc2)CC1 +O=C(Nc1n[nH]c(-c2ccoc2)n1)c1ccc(Oc2cccnc2)cc1 +Cc1cc(NC(=O)c2cc(S(=O)(=O)N(C)C)ccc2F)no1 +CCS(=O)(=O)NCc1cccnc1-n1cccn1 +Fc1ccccc1CNc1ncnc2sccc12 +CCCNC(=O)COc1ccc(C(=O)c2ccccc2)cc1 +O=C(NC1CCCC1)c1ccc2c(=O)n3c(nc2c1)CCC3 +O=C(c1cc2c(F)cccc2[nH]1)N1CCCN(c2cccnn2)CC1 +COC(=O)c1occc1COc1ccccc1Cl +COC(=O)c1cc(N)cc(C(=O)OC)c1NCc1ccc(F)cc1 +NS(=O)(=O)c1ccc(NC(=O)COC(=O)Cn2cnnn2)cc1 +CCn1nnc2ccc(-c3noc(CNC(=O)c4ccccc4)n3)cc21 +N#Cc1ccc(C(=O)N2CCC(c3n[nH]c(C4CC4)n3)CC2)cc1 +CCCC(=O)NCC(=O)c1ccc(OC)c(C(C)C)c1 +CC(=O)N1CCc2cc(C(=O)N3CCCC(c4ccn[nH]4)C3)ccc21 +O=C(CNCc1cccc(O)c1)Nc1ccc(F)c(F)c1F +CC(NC(=O)Nc1cc(-c2ccccc2)on1)C(=O)N1CCOCC1 +CCOc1cccc(-c2nc(C(C)N)cc(=O)[nH]2)c1 +Cc1nnc(C(C)OC(=O)c2cccc(-n3ccnn3)c2)o1 +Cc1ccsc1CN(C)C(=O)NCCNC(=O)CC1CCCC1 +CC(C)Sc1ccc(-c2cc(NC3CC3)ncn2)cc1 +COc1ccc2c(c1)N(Cc1cncs1)CCO2 +Cc1cc(-c2ccc(NC(=O)CC#N)c(C)c2)ccc1NC(=O)CC#N +COc1cc(C)cc2c3c(cnc12)C(=O)OCCO3 +O=C(Nc1cccc2cccnc12)c1ccc(-n2cccn2)cc1 +COc1ncnc(N)c1CNCc1cn(C)nc1C(F)(F)F +CNC(=O)C1CCCN(c2nc(N(C)C)cc(C(F)(F)F)n2)C1 +Cc1ccncc1NC(=O)NC1CCN(c2ccccc2)C1 +CCn1c(-c2cncc(N)c2)nc2cccc(Cl)c21 +N#CC1(C(=O)Nc2cc(-n3nnnc3C3CC3)ccc2F)CCCC1 +CCOc1ccc(NC(=O)CNc2ccc(S(C)(=O)=O)cc2)cc1 +Cc1ccc(C(=O)Nc2ccc(Oc3cccnc3)nc2)nc1 +CCCn1nccc1NC(=O)CCOc1ccccc1F +COc1ccc(C(=O)NCc2ccc3c(c2)CCO3)cc1 +Cn1cc(S(=O)(=O)NCC(C)(C)c2ccc3c(c2)OCO3)cn1 +CCCc1ccc(C(=O)Nc2ncc(C)s2)cc1 +COC(=O)C1=C(C)C(C(=O)OCc2nc3ccccc3o2)=NC1C +CC(NC(=O)Cc1ccc2ccccc2c1)c1ccccn1 +Cc1cccc(C(=O)N2CCN(Cc3noc4ccccc34)CC2)c1 +CCC(=O)c1ccc(OC(C)=O)c(OC(C)=O)c1 +COC(=O)NCC(=O)NCc1ccc(OC)cc1 +O=S1(=O)N=C(Sc2nc3ccccc3o2)c2ccccc21 +c1cc(CN2CCOCC23CCC3)c2c(c1)OCO2 +COc1cc(C)c(C(=O)Nc2ncccc2C)cc1OC +Cc1ccc(-c2c(C)nn3c(N(C)CCO)c4c(nc23)CCC4)cc1 +Cc1ccc2ncc(C(=O)N(CC3CCCCC3)C3CC3)c(=O)n2c1 +CC(C)N1CC(c2ncc(-c3ccc4ccccc4c3)[nH]2)CC1=O +CCCCOc1ccc(C(=O)NCc2ccccc2)cc1N +CCCN(CCc1ccccn1)C(=O)c1cnn(CC)c1 +Cc1cccc(C)c1Oc1ncccc1CNC(=O)C1CCC1 +O=S(=O)(NCCNc1cc(-n2cccn2)ncn1)c1ccccc1 +CCCc1nc(CNc2cccc(F)c2)cs1 +CC(C)(C)n1nc(C2CC2)cc1C(=O)NCCNc1cnccn1 +O=C(NCc1cn2ccsc2n1)c1ccc(F)cc1F +CSc1nnnn1-c1ccc(C(=O)Nc2cccc(C)c2)cc1 +Cc1ccc2nc(C(=O)NC(C)c3ccc(-n4cncn4)cc3)cn2c1 +O=C(CN1CCN(C(=O)C2CCCO2)CC1)NCCC1=CCCCC1 +CC(C)(C)OC(=O)NCCC(=O)N1CCSc2ccccc21 +CN(C)c1cccc(C(=O)N2CCn3c(-c4ccccc4)cnc3C2)c1 +COCc1cccc(C(=O)NC2CCCNC2=O)c1 +O=C(c1cccnc1)N1Cc2nc(-c3ccccc3)sc2C1 +COc1c[nH]c(CN2CCN(c3ccccc3F)CC2)cc1=O +CCn1nnnc1NCc1ccc(-c2ccc(C(C)O)cc2)o1 +COc1ccc(C(=O)OCC2CC=CCC2C)cn1 +CCc1nnc(NC(=O)NCCOc2cccc3ccccc23)s1 +NC(=O)C1CCCN(C(=O)CCc2ccc(OC(F)(F)F)cc2)C1 +CCn1nc(C(=O)Nc2onc3c2CCC3)cc1C +CC(C)(C)c1ccc(S(=O)(=O)CC(=O)Nc2ccccn2)cc1 +Cc1cccc(S(=O)(=O)C(C)C(=O)NC2CC2)c1 +CCCNC(=O)c1nsc(C(=O)NCCC(C)C)c1N +C=CCNC(=O)c1[nH]c(C)c(C(=O)OC(C)C)c1C +COc1ccc(CC(C#N)C(=O)Nc2cccc(C)n2)cc1 +CCN(CC)C(=O)N1CCCC(S(=O)(=O)N2CCOCC2)C1 +CNC(=O)c1cccc(OC(=O)c2ccc3cc(OC)ccc3n2)c1 +COc1cccc(C(=O)Nc2c(C)cnn2-c2ccccc2)c1F +NC(=O)Cc1nc(Cn2cnnn2)n(-c2ccc3c(c2)OCO3)n1 +Cc1ccc(NCc2cc(=O)n(C)c(=O)n2C)cc1 +CC(CNC(=O)C(C)c1ccsc1)c1cccs1 +CC(C)N(Cc1ccccc1)C(=O)c1cccnc1 +COC1CCCC1NS(=O)(=O)c1cc(Br)ccc1N +N#CCSc1nc(=O)n(-c2ccc(Cl)cc2)c2c1CCC2 +O=C(Nc1ccncc1F)NC1CCCCCC1 +CC(N)C(=O)c1ccc2c(c1)N(C(C)C)C(=O)C(C(C)C)O2 +Cn1nc(C(=O)NC(C)(C)C)c(=O)c2ccccc21 +CCc1nc(CN2CCN(Cc3cnc4cc(C)ccn34)CC2)no1 +Clc1ccc(-c2ccnc3nc(-n4cccc4)nn23)cc1 +O=C(NCC1CCCN(C(=O)c2ccco2)C1)c1cccs1 +Cc1ncc(Cl)c(C(=O)N2CC(C)C(O)(C3CC3)C2)n1 +O=S(=O)(NCc1ccccc1)NCc1ccc(CO)cc1 +Cc1ccc(NC(=O)c2ccc(N3CCOC3=O)cc2)cc1F +Cc1ccnn1CCCNC(=O)c1ccc2c(c1)OCO2 +CCC(COC)NC(=O)c1cn(Cc2cccc3ccccc23)nn1 +CC(NC(=O)CCc1nc2ccccc2c(=O)[nH]1)c1ccccn1 +O=C(NCc1ccco1)c1cc(F)ccc1Cl +CC(C1CC1)N(C)C(=O)CNC(=O)c1cccs1 +COc1ccc(C(=O)Cn2ccsc2=O)cc1Br +O=C(CN1C(=O)C2(CCOCC2)c2ccccc21)NCC1CC1 +CCOC(=O)c1cnc2c(c(C)nn2C)c1Oc1ccccc1F +CN(C)S(=O)(=O)c1ccc(-c2ccccn2)s1 +CCNC(=O)c1ccc(CNC(=O)Nc2nc(C3CC3)cs2)cc1 +Cc1cc(C)c(S(=O)(=O)Nc2cccc(O)c2)cc1C +CC(C)c1cc(N(C)CC2(CO)CCCC2)n2nccc2n1 +O=C(C1CCCO1)N1CCCCC1c1ncc(-c2cccc(F)c2)[nH]1 +CC(=O)NCCc1ccc(-c2csc(NC3CCCC3)n2)cc1 +O=C(NCC1CCOC1)c1ccnc(-n2cncn2)c1 +CS(=O)(=O)c1ccc(-c2cc(C(F)(F)F)cc3nc[nH]c23)cc1 +Cc1ccc(Cl)cc1S(=O)(=O)NCc1ccco1 +CC1CCC(NC(=O)CSc2nc3ccccc3o2)CC1 +COc1ccccc1NC(=O)COC(=O)C1CCCCC1 +CCCC(=O)N1CCC(C(=O)Nc2cnn(C)c2)CC1 +CCOc1cc(Cl)c(C(=O)C2CC2)cc1OCC +CCCC1CN(C(=O)c2cc3cc(F)ccc3o2)CCO1 +O=C(Nc1ccc2nncn2c1)c1cc(Cl)c2c(c1)OCO2 +O=C(c1nccn1Cc1ccccc1)N1CCCC1 +O=c1oc2ccccc2n1Cc1nc(-c2ccc3c(c2)OCO3)no1 +N#Cc1cccc(CNS(=O)(=O)c2ccccc2)c1 +CC(=O)C1(c2ccc(F)cc2)Cc2ccccc2C1 +CC(OC(=O)Cn1nc2ccccn2c1=O)c1cccc(F)c1 +CCc1ccccc1OCCc1nc(C2CC2)c(CO)s1 +O=C(COC(=O)c1cc2c(s1)CCC2)Nc1ccc(O)cc1 +COCCNC(=O)c1cncc(-c2ccc(F)cc2)c1 +Nc1[nH]nc(-c2ccsc2)c1-c1ccc(F)cc1 +CCCCN1CC(C(=O)Nc2ccc(C(=O)OC)cc2)CC1=O +O=c1[nH]nc(SCCO)n1Cc1ccccc1 +COc1cc(C(=O)NCCCn2c(C)nc3ccccc32)ccc1C +CC(C)(C)OC(=O)N1CCC(Sc2ncc(F)cn2)CC1 +CC(CCc1ccccc1)NC(=O)Nc1ccn(C)n1 +CCCn1c(SCC(=O)N2CCC(C)CC2)n[nH]c1=O +COc1ccccc1CN1CC(C(=O)N2CCCCC2C)CC1=O +CCn1c(C)ccc(-c2nnc(NCC(C)C)s2)c1=O +C=CCCOC(C)C(=O)N(C)Cc1c(C)nc2sc(C)cn12 +c1cncc(-c2noc(CN3CCOC(Cn4cccn4)C3)n2)c1 +Cn1nc(C(=O)N2CCSc3ccc(Cl)cc32)ccc1=O +COc1ccc(Cl)cc1NC(=O)c1cncn1-c1ccccc1 +CC(CCc1ccccc1)NC(=O)c1cccn1C +O=C1CCc2cc(S(=O)(=O)Nc3ccc(F)cc3)ccc2N1 +COCCCNC(=O)c1ccccc1NC(=O)c1ccccc1C +CC(C)CCCCNC(=O)C1CCCN1C(=O)c1cccs1 +Cc1cc(C(=O)N2CC(C)OC(C)C2)nc(N2CCCCCC2)n1 +C=CCN(CC=C)S(=O)(=O)c1cccc(F)c1C#N +O=C(CCn1ccccc1=O)NCc1ccc(F)cc1 +COc1cccc(-c2nc3ccc(Cl)cn3c2C(C)O)c1 +CCC(C)NC(=O)NCCn1cnc2ccccc21 +CC(NC(=O)Nc1cccnc1-n1cncn1)C(=O)N1CCCCC1 +Cc1nc(C)c(C(=O)Nc2cc(-c3cccc(F)c3F)n[nH]2)o1 +CCNC(=O)CN(C)C(=O)c1cnc(C(C)(C)C)s1 +CN(CC(F)(F)F)C(=O)CN1CCN(Cc2cccs2)CC1 +COC(=O)N(C)c1ccc(NC(=O)NCc2cccc(C)c2)cc1 +NC(=O)C1CCN(C(=O)C(c2ccccc2)N2CCc3ccccc32)C1 +CCS(=O)(=O)NCc1ccc(-c2nc(C(C)(C)OC)no2)cc1 +O=C(c1cccc(F)c1)N1CC(OCc2ccc(F)cc2Cl)C1 +Cn1cccc1C(=O)N1CCCC1CC(=O)c1ccccc1 +N#Cc1cccc(SC2CCN(CC(F)(F)F)C2=O)c1 +CCc1nc2cc(Cl)c(Cl)cc2n1CCO +Cc1cc(C(N)=O)ccc1NC(=O)CCNC(N)=O +CC(=O)NC(CC(=O)N1CCCC(C)C1)c1ccc(Cl)cc1 +CCOC(=O)c1cc2cc(NC(=O)C3CC3)ccc2s1 +Cc1ccc(NC(=O)CSc2nnnn2C)cc1C +Cc1cc(NC(=O)NCCCOCC2CCOC2)c2ncccc2c1 +COc1ccc(C(=O)N2CCCC2)cc1-c1ccccc1 +Nc1ccc2c(c1)N(C(=O)c1ccc(C(F)(F)F)cc1)CC2 +COC(=O)CCCNc1nccc2c(N)c(Cl)ccc12 +Cc1nc(CSc2nnnn2C2CCCC2)nc2ccccc12 +CCCC(=O)N1CCC(n2nnc3ccccc3c2=O)CC1 +COc1c(C)cc(-c2nn(C)c(C)c2N)c(C)c1C +COc1ccc(OC)c(C(=O)N=c2[nH]nc3ccccn23)c1 +COc1ccc(C(=O)C(C)n2cc(Br)cn2)cc1 +Cc1ccc(C(O)CNC(=O)c2ccc3c(c2)OCO3)c(C)c1 +Cc1nc(C)n(CC(C)C(=O)N(C)Cc2cccc3ncccc23)n1 +CCOC(=O)CCNC(=O)Nc1ccc(OC)cc1C +O=C(NCc1ccccc1)c1cc2scnc2[nH]1 +CC(C)c1cc(C(=O)N2CCCC(C(=O)c3ccccc3F)C2)on1 +O=C1CCC(C(=O)NC2CCc3c(Br)cccc32)N1 +CCC(CC)C(=O)NCCc1sc(C)nc1C +CN(C)C(=O)CSc1nc(-c2ccccc2)c(-c2ccccc2)[nH]1 +N#Cc1ccc(C(=O)Nc2ccc3c(c2)CCC3)cc1 +N#CCn1c(-c2ccccn2)nc2cc3c(cc21)OCO3 +Cc1ccc(-c2ncco2)cc1NC(=O)c1cc2c(s1)CCOC2 +CC(C)N(Cc1cnn(C)c1)C(=O)c1cnc(-c2cnn(C)c2)s1 +Cc1noc(C)c1S(=O)(=O)NCC(O)c1cccn1C +Cc1cc(C(=O)NCC(=O)N(C)C(C)C)c(C)o1 +O=C(C1CCN(c2ccc(-n3cccc3)cn2)CC1)N1CCCC1 +COc1ccc(NC(=O)NC2CCCCC2)cc1N1CCCC1=O +CC(N(C)C(=O)c1ccc(OCC(F)F)nc1)C1(C)CC1 +O=C(NCCOCCO)c1cccc2nccnc12 +CCN(CCc1ccncc1)C(=O)CCc1ccccc1N +CC(c1nnnn1-c1ccccc1)N1CC2OCCN(C)C2C1 +Cc1ccc(C=Cc2nc(SCCO)n[nH]2)o1 +CN(C(=O)c1ccc2c(c1)OCO2)C(C#N)c1ccccc1F +COc1cccc(C(=O)Nc2ccccc2CC(N)=O)c1F +COCCn1cc(NC(=O)NC2CCCc3ccccc32)cn1 +COc1ccc(CS(=O)(=O)n2cc(-c3ccccc3)c(N)n2)cc1 +Cc1csc(NC(=O)C(C)n2nnc3ccccc3c2=O)n1 +CCc1nnc(NC(=O)CCCOc2ccc(Cl)cc2C)s1 +COc1cc(S(=O)(=O)NCc2cccnc2)c(OC)cc1Cl +CCCCn1ncc(C)c1NC(=O)c1[nH]nc(CC)c1C +CC(CC#N)N(C)CC(=O)c1ccc(Cl)cc1Cl +O=S(=O)(c1ccc(F)cc1)N1CCCCCC1 +CCOC(=O)C(c1nc(C(C)(C)C)cs1)C(C)C +CCOc1ccccc1CN1C(=O)C(=O)c2ccccc21 +Cc1ccc(C(C)C)cc1S(=O)(=O)n1cccn1 +CC1CN(CCNC(=O)c2cncn2-c2ccc(F)cc2)CC(C)O1 +CSc1ncccc1C(=O)Nc1ccc2c(c1)C(=O)N(C)CCO2 +Cc1ccc(NC(=O)C2CCCN(Cc3scnc3C)C2)nc1 +CCC(C)NC(=O)c1ccc(NCC(=O)OC)c(C)c1 +COc1cccc(C(=O)NCC2CCCN2S(C)(=O)=O)c1F +CCOC(=O)c1nc2sc(C(CC)CC)nn2c1C#N +COc1cccc(Cc2nnc(NC(=O)NC(C)C)s2)c1 +CCCn1nnc(NC(=O)c2ccc(C(C)C)cc2)n1 +CCNC(=O)c1ccc(CNC(=O)c2n[nH]c3ccccc23)cc1 +CCOC(=O)CSc1nc2ccsc2c(=O)n1C +Cc1nc(C2CCC2)nn1Cc1cnn(-c2ccccc2)n1 +CN(Cc1nc(-c2ccccn2)no1)c1ncnc2c1CCC2 +CCC(C)NC(=O)CN1C(=O)COc2ccc(CO)cc21 +CC(=O)Nc1cc(NCc2c[nH]nc2C)ccc1C +O=C(Cn1nc(N2CCOCC2)ccc1=O)Nc1cccc(Cl)c1 +O=C(NCC(=O)N1CCCC1)c1ccccc1Br +Cc1cc(CC2COCC2NC(=O)c2nccn2C)on1 +CCNC(=O)CNC(=O)Nc1cc(-c2ccccc2)on1 +Cc1cc(C)c(N2C(=O)C(C)CS2(=O)=O)c(Cl)c1 +COCCn1cc2c3c(cccc31)CN(C(=O)c1ccc(C)cc1)CC2 +Cc1ccccc1C1CN(Cc2ccc(S(C)=O)cc2)CCO1 +CC(C(=O)NC1CCCCC1)n1nnc(-c2ccccc2)n1 +Cc1ccc(C(C)C)c(OC(=O)Cc2nc3nc(C)cc(C)n3n2)c1 +CC(C)CC(=O)Nc1cc(Cl)ccc1-n1cncn1 +COCc1ccccc1CNC(=O)N1CC(C)CC(C)C1 +Fc1cccc(F)c1CN1CCc2nnc(C3CCCO3)n2CC1 +CC(=O)NC(C)(C)c1noc(-c2ccc(OC(F)F)cc2)n1 +CC1C(=O)N(c2ccc(F)cc2)CCN1C(=O)CC(C)(C)C +O=C1CC(C(=O)Oc2ccc(-n3cnnn3)cc2)c2ccccc2N1 +CCN(CC)S(=O)(=O)N1CCN(c2cn[nH]c(=O)c2Cl)CC1 +COC(=O)c1ccsc1NC(=O)c1ccn(C(C)C)n1 +N#CC(CCN1CCCc2ccccc21)NC1CC1 +O=C(c1ccccc1F)N(Cc1ccco1)Cc1ccco1 +COC(=O)CCC(=O)Nc1ccc(C(N)=O)cc1 +CCCOc1cccc(C(=O)Nc2ccccc2C(=O)NC)c1 +CCN(c1ccccc1)S(=O)(=O)c1ccc(OC)c(NC(C)=O)c1 +CC(=O)N1CCCC1C(=O)Nc1cccc(Cl)c1 +COc1ccc(OCC(=O)N(C)Cc2cc(C#N)ccc2F)cc1F +Nc1c(Cl)ccc2c(C(=O)N3CCCCC3)nccc12 +CCC(C)NC(=O)Cn1nnc2c(C)nn(C)c2c1=O +CC1(C)C(=O)Nc2ccc(C(O)C(=O)NC3CC3)cc21 +O=C1NCC(C(=O)NCc2ccc(COCc3ccccc3)cc2)N1 +CCCOc1cccc(NC(=O)c2ccccc2-n2cnnn2)c1 +COc1ccc(Cl)cc1S(=O)(=O)NC(C#N)C(C)C +CC1CN(C(=O)c2cccnc2)CC12CCN(C)C2=O +CCn1nccc1C(=O)Nc1nc(-c2ccc(C)cc2C)cs1 +CC(O)CC(C)CNC(=O)C12CC3CC(CC(C3)C1)C2 +CC(C)Oc1ccccc1Nc1nnc(SCCO)s1 +O=C(NCc1cccs1)c1ccc(S(=O)(=O)CCO)cc1 +COC(=O)CCNC(=O)C(N)c1cc(F)ccc1C +COc1cc(CNC(=O)NCCc2ccc(F)cc2C)ccn1 +NC(=O)c1csc(NC(=O)c2cncc(Br)c2)n1 +Cn1c(=O)c2c(ncn2CC(=O)Nc2ccc(Cl)cc2)n(C)c1=O +CC(=O)NCc1ccc(-c2csc(NC(C)=O)n2)o1 +Cn1cc(CC(=O)Nc2ccc(OC(F)(F)F)cc2)c2cccnc21 +COc1ccc(OC)c(NC(=O)CCn2cnnn2)c1 +Cc1cc(OCC(=O)Nc2c(C)n[nH]c2C)ccc1C(C)C +CN(C)C(C(=O)N1CC2C3CCC(O3)C2C1)c1ccc2c(c1)OCO2 +CC(CCc1ccccc1)NC(=O)c1cnc(C2CCCO2)s1 +Cc1nc(CNc2cccc(C(=O)N3CCCC3)c2C)no1 +N#Cc1cccc(CSc2nnc(C3CC3)n2CC(N)=O)c1 +Cc1c(NCc2nc(-c3ccccc3)no2)cccc1C(N)=O +O=C(NC1CCCCC1)N1CCN(c2n[nH]c(=O)[nH]c2=O)CC1 +Cc1ccc2nnc(C#N)c(NCCN3CCOCC3)c2c1 +CCC(C)C(C)NC(=O)CCc1c(C)nc2c(c(OC)nn2C)c1C +O=C(COc1ccccc1)NCc1ccnc(OC2CCC2)c1 +Cc1nc(NC(=O)C(C)C)sc1C(=O)N(C)C +CC1CCN(C(=O)Cn2ncc(Cl)c(Cl)c2=O)CC1 +Cc1ccc(Cl)cc1-n1nnc(C#N)c1-c1ccncc1 +Cc1cccc(S(=O)(=O)N2CCCC(c3nccn3C(C)C)C2)c1 +Cc1nc2ccccc2n1CCNS(N)(=O)=O +CC1=C(C(=O)OC(C)(C)C)C(c2ccc(O)cc2)NC(=O)N1 +CC(=O)Nc1nnc(SCCCC2CCCC2)s1 +OCC(O)CNc1cc(C(F)(F)F)ccc1Cl +O=C(NCc1cccs1)c1ccc(-c2cscn2)cc1 +CNC(=O)CNC(=O)Cc1ccc(Cl)c(Cl)c1 +COc1ccc(CO)cc1OCC(=O)NC(C)C +Cc1ccccc1CN(C)C(=O)C(C)Nc1ccc2[nH]c(=O)[nH]c2c1 +O=C1OCCC1Sc1nnc(-c2ccccc2Cl)o1 +Cc1ccccc1CNc1nc(N(C)C)nc2c1cnn2C +CCCCn1cccc(-c2nnc(NC(C)CC)s2)c1=O +CCOC(=O)CCc1cc2c(C)cc(=O)oc2cc1OCC#N +COc1cccc2c(CO)cn(CC(O)CO)c12 +COc1ccc(Cl)cc1S(=O)(=O)N1CCC(O)CC1 +O=C(CCc1ccccc1)Nc1nnc(-c2ccsc2)o1 +CN(CCCc1cnn(C)c1)C(=O)C1(c2ccccc2F)CC1 +COC(=O)c1ccccc1NC(=O)CSc1ccc(N)nc1 +Cc1ccc(-n2ccnc2-c2ccc(C(N)=O)cc2)cc1 +Cc1occc1CN(C)C(=O)NCc1ccnc(OC(C)(C)C)c1 +O=C(CCn1cnnn1)OCC(=O)c1ccc(Br)cc1 +Cc1n[nH]c(C)c1CCC(=O)N(C)C(C)c1ccc(Cl)cc1 +O=C(NCc1cccs1)c1ccc2c(c1)OCCO2 +CCN(CCC(=O)OC)C(=O)Cn1c(C)c(C)sc1=O +CCN(CC)C(=O)c1cc2c(s1)CCC(C)C2 +O=C(Cc1ccc[nH]1)NC1CCN(c2ccccc2)C1 +O=C(COC(=O)COc1ccc2c(c1)CCC2)Nc1ccccc1 +CN(C)C(=O)c1ccc(CC2CCOc3ccccc3C2)nc1 +CCCc1nc(NCc2ccc(C)cc2)cc(OC)n1 +CCc1cccc(OCC(=O)Nc2cc(N)ccc2F)c1 +Cc1nc2sc3c(c2c(=O)n1CCC#N)CCC(C)C3 +Cc1nn2c(=O)cc(CN3CCCc4cc(F)ccc43)nc2s1 +CC(c1ccsc1)N1CCN(C(=O)C2CCCO2)CC1 +CCN(C)c1ccc(C(=O)NCCC(=O)N2CCOCC2)cc1 +O=C(Cc1n[nH]c2ccccc12)Nc1cccc(-n2cccn2)c1 +Cc1ccc(S(=O)(=O)NCC(O)c2cccs2)c(C)c1 +CC1=NC(=O)C(CCC(=O)Nc2ccc(C)cc2F)C(C)=N1 +CCc1cc(=O)[nH]c(SCC(=O)Nc2cccc(C(C)=O)c2)n1 +CCCCn1nc(C2CCCC2)nc1C(C)N1CCCC1=O +Cc1ccc(C(=O)NCc2nnc3nc(C)cc(C)n23)cc1 +CC(C)n1cc(C(=O)N2CCC(c3nc4ccccc4o3)CC2)cn1 +CCOc1ccc(C(C)NC(=O)N(C)Cc2ccccn2)cc1 +CNc1snc(C)c1C(=O)NCc1cccs1 +COc1ccccc1OCc1ccc(C(=O)N(C)C2(C#N)CCC2)o1 +CN(C(=O)c1ccccc1)S(=O)(=O)c1ccccc1 +CC(=O)N1CCCN(C(=O)c2cccc(C#N)c2)CC1 +O=C(NCc1ccc2c(c1)OCO2)c1ccccc1F +COc1cccc(C(=O)OCc2cn3ccccc3n2)c1F +CS(=O)c1cccc(NC(=O)C2(c3ccc(Cl)cc3)CC2)c1 +Cn1c(NC(=O)c2ccc3ccccc3c2)cc(=O)n(C)c1=O +CCN(CC(=O)NS(=O)(=O)N1CCCC1)c1ccccc1 +CC(C)c1cc(C(=O)N2CCc3ccccc3C2)no1 +COCC(=O)N1CCC2(CC1)NC(=O)CC2c1ccccc1 +CCOc1ccc2nc(NS(=O)(=O)N(C)C)sc2c1 +N#Cc1ccc(Cn2ncc3ccccc3c2=O)cc1 +CCc1ccc(N2CC(C(=O)NC(C)C)CC2=O)cc1 +CCn1c(C)cc(C(=O)Nc2cccc(NC(=O)C3CC3)c2)c1C +CN(CCN1CCCC1=O)c1nnc(Cc2ccc(F)cc2)s1 +Cc1ccc(C(=O)NCc2ccc(Cn3ccnc3)cc2)s1 +CCNC(=O)N1CCc2ccc(NC(=O)NCC(C)(C)C(N)=O)cc21 +COc1ccccc1CCC(=O)N1CCCC1c1nc(C)cc(O)n1 +Cc1cc(C)c(S(=O)(=O)NCC(C)Cn2nc(C)cc2C)c(C)c1 +CC(=O)Nc1ccc(S(=O)(=O)NC(C)c2ccncc2)cc1 +O=C(Cc1cccs1)NCCCS(=O)(=O)c1ccccc1 +CC1CC(=O)c2c(OCC(=O)NC3(C#N)CCCCC3)ccc(F)c21 +COc1ccc(CN(C)S(=O)(=O)Cc2cccc(Cl)c2)cc1 +CCCN(CC1CC1)C(=O)c1ccc(Cl)c(S(C)(=O)=O)c1 +Cn1nccc1CNC(=O)NCc1ccc(F)cc1C(F)(F)F +O=C(Nc1ccc2c(c1)COC2)c1ccc(-n2cncn2)c(F)c1 +Cn1cc(CNC(=O)Nc2ccc(C#N)c(Cl)c2)cn1 +CC(Sc1nnc(-c2ccccc2)n1N)C(=O)N(C(C)C)C(C)C +CCc1ccc(S(=O)(=O)N2CCCC2c2cccnc2)cc1 +CCc1cc(C(=O)Nc2ccnc(C)c2)sc1C +COc1ccccc1CCNC(=O)c1ccc(-n2nnnc2C)cc1 +CC(=O)N1CCCc2cc(NC(=O)C3CCCC3)ccc21 +COC(=O)C1CCCN(c2ccc(OC)c3nc(N)nn23)C1 +CCOc1ccccc1OC1CCN(C(=O)Cc2cccs2)CC1 +CC(=O)N1CCCN(C(=O)c2cc(S(N)(=O)=O)ccc2F)CC1 +CCc1ccc(C(=O)N2CCCC(C(N)=O)C2)s1 +O=C(CCn1nc(-c2cccs2)oc1=O)N1CCc2ccccc21 +COc1ccc2oc(C)c(C(=O)Nc3ccc(-c4cc[nH]n4)cc3)c2c1 +Nc1cccc(Cn2c(CCO)nc3cc(F)ccc32)c1 +Cc1ccc(C(C)NC(=O)CCc2c(C)noc2C)o1 +CC(Cc1ccsc1)Nc1cc(N2CCCC2CO)ncn1 +Cc1ccc(C(C)C)cc1C(=O)CCN1CCC(=O)CC1 +CCN(CC)C(=O)CN(C)S(=O)(=O)c1cccs1 +O=C(Nc1ccccc1N1CCCC1=O)c1cccc2[nH]ccc12 +CN(CCc1ccncc1)C(=O)CC(C#N)c1ccc(F)cc1 +Cc1cc(C)n(-c2ccccc2CNC(=O)c2ccc[nH]2)n1 +COc1cc(C(=O)NCC(F)(F)F)ccc1OCc1ccccc1 +CC(CC(=O)NCc1nc(-c2cccs2)no1)C1CC1 +Cc1nc[nH]c1-c1nccn1CCN1CCOC1=O +CC1(C)CC(=O)N(CC(=O)NCc2cccnc2)c2ccccc21 +COc1cc(C(=O)NCc2cccc(-n3cncn3)c2)ccc1C +CCC(=O)N1CCCN(C(=O)c2scnc2C2CC2)CC1 +CC(C)CC(=O)NCCNC(=O)C1CC(=O)N(c2ccccc2)C1 +CCCOCC(=O)N1CCNC(=O)C1c1ccc(C(F)(F)F)cc1 +COc1ccc(C(C)=O)cc1CC(=O)Nc1ccc(N(C)C)nc1 +O=C(CN1CCCCC1=O)N1CCCN(C(=O)c2ccccc2)CC1 +COCCN(Cc1ccccc1)C(=O)c1cc(C)oc1C +CCCC(C)N(C)C(=O)Nc1ccc(NC(C)=O)c(OC)c1 +COC(=O)c1cc(-c2c(OC)cc(OC)cc2OC)no1 +COc1cccc(CNS(=O)(=O)c2cn[nH]c2C)c1 +COc1cccc2c1OCC(NC(=O)NC1CCCC1)C2 +O=C(CCc1ccc(-c2ccccc2)o1)NCc1nnc2ccccn12 +O=c1ccccn1Cc1cc(Cl)c2c(c1)OCCCO2 +CC(C)(C)OC(=O)NCCNS(=O)(=O)c1ccc(N)cc1 +CN(C)C(=O)CCCC(=O)Nc1cccc(C#N)c1 +CCS(=O)(=O)c1ccccc1C(=O)OCC1CCCCO1 +Cc1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)[nH]n1 +CC(C)C(C)(C#N)NC(=O)Cc1cccc(OCC#N)c1 +Cc1nc(CNC(=O)c2cn(C)nc2C(C)(C)C)sc1C +CCN(Cc1ccc2c(c1)OCO2)C(=O)Nc1nnc(C2CC2)s1 +Cc1noc(C(C)OC(=O)CCc2cc(Cl)cs2)n1 +CSc1nc(N2CCCC2)nc(-c2ccco2)c1C#N +CC(Sc1n[nH]c(N)n1)C(=O)NC1(C#N)CCCCC1 +Cc1c(C(C)NC(=O)c2ccco2)cnn1-c1ccc(F)cc1 +Clc1ccc(Cn2ccnc2-c2cnccn2)cc1 +OC1CCCc2c1[nH]c1ccc(Br)cc21 +Cc1cnn(CCC(=O)NCCc2ccccc2Cl)c1 +Nc1cc(CCC(=O)N2CCN(CCO)CC2)ccc1Cl +Cc1nnc(NC(=O)CSc2nc(C)c(CC(C)C)[nH]2)s1 +CN(C)C(=O)N1CCN(CCOc2cccc(C#N)c2)CC1 +CCCC(C(=O)N1CCN(C(=O)c2ccco2)CC1)c1ccccc1 +COc1cc(CCC(=O)NC2CC2)cc(OC)c1OC +O=C(CCSc1nc2ncccn2n1)Nc1ccc(F)cc1 +O=C(COc1ccccc1F)NCc1cc(-c2ccco2)on1 +CCN(Cc1ccccc1)C(=O)C(C)N1CCN(C(=O)COC)CC1 +CC(C)c1cc(C(=O)Nc2ccc(Oc3cccnc3)nc2)n(C)n1 +Cc1noc(CSc2nc(N)c3c(C)c(C)sc3n2)n1 +CCOc1ccccc1NC(=O)Cn1cnc(N)n1 +CCOCC1CCCN(C(=O)Nc2cccc(-n3nnnc3C)c2)C1 +CCN(CCCNc1ccc(Br)cn1)S(C)(=O)=O +CN(C)c1nc(Oc2ccc(=O)n(CC(N)=O)n2)nc(N(C)C)n1 +Cc1nn(C)c(C)c1OCC(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +COc1cc(OC)nc(-c2cccc(NC(C)=O)c2)n1 +Cc1ccccc1OCCNC(=O)C1CC(=O)N(C)C1 +CC(C)NC(=O)CNc1ccc(C(=O)NC(C)c2ccccc2)cc1 +O=C(NCCc1csc(-n2cccn2)n1)c1cccs1 +O=C(Nc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1)C1CCC1 +NC(=O)c1cccc2c1CCCN2C(=O)c1ccnc2ccccc12 +O=C(Cn1cccn1)N1CCCc2cccc(O)c21 +c1ccc(-n2nnnc2CNc2ccc(-n3cccn3)cc2)cc1 +Cc1ccccc1CN(C)C(=O)Cc1csc(-c2ncccn2)n1 +CNc1nc(-c2c(C)cc(C)n(CCC(C)C)c2=O)cs1 +CCCC(C)NC(=O)c1cn(CC#N)c2ccccc12 +CCCCC(=O)N1CCCC1C(=O)c1cccc(OC)c1 +NS(=O)(=O)Cc1ccc(NC(=O)Cc2ccccc2F)cc1 +Cc1nc(CNc2cccc(OCCc3ccccc3)c2)no1 +O=C1CC2(CCN(C(=O)c3ccccc3)CC2)Oc2ccccc21 +CC(C)(C)c1n[nH]c(C2CN(CCn3cncn3)CCO2)n1 +CNC(=O)c1ccc(COc2ccc3ccc(=O)oc3c2)cc1 +Cc1ccc(NC(=O)NCCc2c[nH]c3ccc(F)cc23)cc1 +COc1cc(C2NC(=O)NC(C(C)C)=C2C(=O)OC(C)C)ccc1O +Cc1ccc(NC(=O)CN(C)C(=O)C2CC=CC2)nc1 +Nc1cc(N)nc(SCc2ccc(OCc3ccccn3)cc2)n1 +Cc1ccc(OCC(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1C +CCS(=O)(=O)Nc1ccc(-c2noc(-c3ccccc3)n2)cc1 +COc1ccc(F)c(NC(=O)NCCc2cn3ccccc3n2)c1 +CC(NC(=O)Nc1cccc(C(=O)N2CCCC2)c1)c1ccncc1 +Cn1cc(S(=O)(=O)N2CCC(NC(=O)CCC3CC3)CC2)cn1 +O=C(NCC(=O)N1CCCc2ccccc21)c1ccc2[nH]cnc2c1 +O=C(Nc1nc2ccccc2s1)c1cnn2c1OCCC2 +O=C(NCCCC1CCCCO1)NCc1ccc(Cl)cn1 +COc1ccc(C2CCCCCC2O)cc1OC +CS(=O)(=O)c1ccccc1-n1cc(Nc2nccnc2C#N)cn1 +Cc1cc(F)ccc1NC(=O)Cc1nnc(-c2sccc2C)o1 +CCCCc1nc(C)sc1C(=O)NCCc1c[nH]cn1 +COCCNc1cc(-c2nccc3occc23)c2cc[nH]c2n1 +O=C1CC(c2cccs2)Cc2c1cnn2-c1ccccc1 +COc1ccc(NS(=O)(=O)c2ccccc2C)cc1N +N#Cc1ccc(N2CCC(NC(=O)C3CC=CC3)CC2)nc1 +COC1CCCC(OC(=O)C(NC(=O)c2cccs2)C(C)C)C1 +O=C(c1cc(F)cc(F)c1)N1CCC2(CC1)OCCO2 +Cc1ccc(NC(=O)NC(C)CCCO)cc1C(N)=O +O=C(CCNC(=O)c1cc2cccnn2n1)NC1CCCC1 +N#Cc1cccc(NC(=O)c2cnn(-c3ccccc3)n2)c1 +COCCc1noc(N)c1-c1c(F)cccc1Cl +CCc1ccc(S(=O)(=O)NCCc2ccccn2)cc1 +CCc1nc(CNC(=O)Nc2ccccn2)cs1 +Cc1n[nH]c(C)c1CCc1n[nH]c(=O)n1Cc1cccs1 +CCOc1cccc(CNC(=O)N(C)Cc2nccn2C(F)F)c1 +Cc1cc(C)cc(CCNC(=O)c2cccn2C)c1 +CC(C)c1nnsc1CNC(=O)C(c1cccnc1)N1CCCC1 +OC1=Nc2c(cnn2Cc2ccccc2Cl)C(c2cccnc2)C1 +Cc1ccccc1C(=O)NCC(c1ccco1)N1CCOCC1 +CCCOc1ccc(NC(=O)c2cccc(-n3cnnn3)c2)c(C)c1 +CNC(=O)C1(C)CN(C(=O)c2cnc(C)cn2)CCO1 +COC(=O)N1CCOC(c2cc(Cl)cc(Cl)c2)C1 +CN(Cc1cccc(C#N)c1)C(=O)CCC(=O)c1ccccc1 +CC(C)C(NC(=O)c1ccccc1)C(=O)N(C)Cc1ccsc1 +CCOc1ccc2ccccc2c1C(=O)NCc1ccco1 +CCCN(C)S(=O)(=O)c1ccc(C)c(C(N)=O)c1 +O=C(CNC(=O)N1CCCCCC1)N1CCc2ccccc2C1 +N#Cc1ccc(NCc2ccc(F)cc2)cc1C#N +CCc1noc(CN(C)C(=O)C2CC(=O)N(C3CCC(C)CC3)C2)n1 +COC(=O)CNc1ccc(Cl)cc1C(F)(F)F +COc1c(Br)cc(C(N)=O)cc1Br +Cc1cc(C)n(-c2ccc(C(=O)Nc3ccc4c(c3)OCO4)cc2)n1 +COc1ccc(Cl)c2c1NC(=O)C2NC(C)=O +CCc1cc(C#N)c(NC(=O)COc2ccccc2C#N)s1 +CC(C)CC(C)OCCC(=O)NC1CCCC1C +Cc1csc(CNc2ccc(C(=O)NC(C)C)cc2)n1 +Nc1ccc(NCCNC(=O)c2ccccc2F)nc1 +CCOc1ccc(Oc2ccc(NC(=O)CNC(N)=O)cc2)cc1 +Nc1ccc(OCc2cccc(Br)c2)nc1 +COc1ccc(C(O)CCC(=O)NCC(C)C)cc1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1ccc(N2CCNC2=O)cc1 +Clc1ccccc1Cn1ncc2c(N3CCOCC3)ncnc21 +COCC(NC(=O)Nc1cc(F)ccc1OC)c1ccco1 +CCOC(=O)c1c(C)[nH]c(C(=O)NCCOC)c1C +COc1cccc2c1OC1(C)CC2C(C(C)=O)C(=O)N1 +COc1cc(Nc2cc(-n3nc(C)cc3C)ncn2)cc(OC)c1 +COC(=O)N1CCC(NC(=O)C(C)Oc2ccc(F)c(F)c2)CC1 +CC(=O)c1c(C)[nH]c(C(=O)Cn2nnc(-c3ccccc3)n2)c1C +Cc1cccc(NC(=O)Cn2cc(Cl)c(=O)[nH]c2=O)c1C +CC(C)NC(=O)CCCC(=O)NC1(C)Cc2ccccc2C1 +Cc1nn2cc(C(=O)Nc3ccc4c(c3)OCO4)nc2s1 +CC(C)Nc1nc(C2CC(=O)N(Cc3ccccc3)C2)cc(=O)[nH]1 +COc1ccnc(NC(=O)C2CCN(C(=O)N(C)C)CC2)c1 +CNc1ncc(C(=O)NCC2CCCOC2)cc1Cl +CC(Oc1ccccc1C#N)C(=O)Oc1cccc(-n2cccn2)c1 +O=C(Nc1ccn(Cc2cccc3cccnc23)n1)c1ccccc1F +C#CCNC(=O)c1csc(-c2ccc(C)cc2C)n1 +COc1cccc(C(=O)NC2CCCc3ccccc32)c1O +Cc1ccccc1CC(=O)NCCNS(C)(=O)=O +COc1cc(OC)cc(C(=O)Nc2ccc(N)cc2Cl)c1 +COc1ccc(OC)c2c1CN(Cc1nnnn1C1CC1)CC2O +Cc1nc(C2(NS(=O)(=O)c3ccc4c(c3)CCC4)CCC2)no1 +Cc1csc(NC(=O)CCc2nc(C(C)C)no2)n1 +Cn1cc(C(=O)Nc2cc(Cl)ccc2F)ccc1=O +COc1ccc2c(=O)c(NC(=O)NCC3CC3)c[nH]c2c1 +COc1cc(C(=O)N2C3CCC2CC(=O)NC3)ccc1OC(F)F +CCC(C)Oc1ccc(NC(=O)c2ccnc(-n3ccnc3)c2)cc1 +Cn1cnc(CNC(=O)NC(C)(C)c2ccc(F)cc2Cl)n1 +O=S(=O)(CCOc1ccc(F)cc1)Nc1nc2ccccc2[nH]1 +COCCC(=O)Nc1ccc(Sc2nc(C)cs2)c(Cl)c1 +CCC1Nc2cc(F)ccc2N(C(CC)C(=O)OC)C1=O +Cc1ccc(-n2nnc3c(=O)n(CC(=O)c4ccccc4)cnc32)cc1 +CC(=O)c1ccc(S(=O)(=O)N(C)C(C)C)cc1 +CCc1cc2oc(=O)cc(COC(=O)c3cnn(C)c3)c2cc1Cl +CC(C)C(=O)N1CCCC1CS(=O)(=O)c1ccccc1 +CN(Cc1c(F)cccc1Cl)C(=O)COc1cccc(C#N)c1 +COCCNC(=O)N1CCN(CC(O)c2ccco2)CC1 +CC(C)CC1(CNC(=O)c2cccc(C(=O)N(C)C)c2)CCCC1 +CCC1(C)Cc2c(sc3nc(SCCO)nc(N)c23)CO1 +CCCn1c(SCCOc2ccccc2Cl)n[nH]c1=O +CCCC(C)C(=O)Nc1ccccc1C(=O)NC(C)C +Cc1noc(NC(=O)c2cc3cccc(Br)c3o2)n1 +N#Cc1ccc(C(=O)NCC(=O)NC2CC2c2ccc(F)cc2)cc1 +CNC(=O)CCNS(=O)(=O)c1ccc(OC(F)(F)F)cc1 +CCCNS(=O)(=O)c1ccc(CCC(=O)N2CCOCC2)cc1 +O=C(CCCc1ccccc1)Nc1cccc2cn[nH]c12 +COCC1c2c(cnn2C)CCN1S(=O)(=O)c1ccccc1C +CCOC1CCCN(S(=O)(=O)c2ccc3c(c2)CCC(=O)N3)C1 +O=C(CCN1C(=O)CCc2ccccc21)NCCc1ccc(F)cc1 +Brc1cnc(OC2CCCCC2)nc1 +CC1CN(C(=O)COCc2ccccc2)CC1(O)C1CC1 +Cc1cc(C2CCCN2C(=O)Nc2cn(C(C)C)nn2)on1 +CNC(=O)c1cn(CCC#N)nc1-c1cccc(Br)c1 +CN1C(=O)CCCc2cc(C(O)c3cccs3)ccc21 +CC(C)(C)n1ncc2cnc(N3CCN(c4nccs4)CC3)nc21 +Cc1nc(C)c(C2NCCc3cc4c(cc32)OCO4)s1 +O=C(Nc1ccc2c(c1)COC2=O)c1ccccc1 +COCCOc1ccc(NC(=O)NCc2ccoc2)cn1 +Cc1cnn(CCC(=O)Nc2ccc3c(c2)CCC3)c1 +Cc1cccc(NC(=O)CNC(=O)c2cccc(Cl)c2)c1 +COc1ccccc1N1CCC(CNC(=O)NCc2cccs2)C1 +COc1cccc(C(=O)Nc2ccc(N3CCCCC3)cn2)c1F +CC(C)N(C)C(=O)c1ccc(=O)n(Cc2ccccc2)n1 +N#CCSc1nccn1-c1cccc(Cl)c1Cl +O=c1n(Cc2ccccc2)nnn1-c1cccs1 +CC(=O)Nc1cc(C(=O)NCCCC2CCCC2)ccc1C +CC(C)c1nnc2n1CCN(C(C)c1nc3ccccc3c(=O)[nH]1)C2 +Cc1c(Cl)cccc1-n1ccnc1S(=O)(=O)CC(N)=O +CCOC(=O)CCNC(=O)Nc1ccccc1F +CC1Cc2c(sc3nc(C(C)(C)C)nn23)CN1 +O=C(OCC1CCCO1)c1ccc(OC(F)(F)F)cc1 +CC(=O)NCC(=O)N1CCOC2(CCCC2COC(C)C)C1 +CCOc1coc(C(=O)Nc2cc(C)ccc2OC)cc1=O +COCc1ccccc1CNC(=O)C(C)Oc1ccccc1 +Cc1ccncc1C(=O)NCCC1CN(C2CCOCC2)CCO1 +COc1cccc(C(=O)NC2CCSc3ccc(Cl)cc32)c1 +CC(C)Cc1nnc2sc(CN3CCOc4ccccc4C3)nn12 +Cc1ccc(NC(=O)c2nccn3ccnc23)c2cccnc12 +CCCCNC(=O)c1coc(COc2cccc3cnccc23)n1 +CC(C)CN(c1cn[nH]c1)S(=O)(=O)c1cccc(C#N)c1 +CC(Cn1cccn1)NC(=O)c1cc(C2CC2)[nH]n1 +CC(NC(=O)c1cncn1-c1ccc(F)cc1)C1CC1 +NC(=O)c1cc(C(=O)Nc2cccc(Cl)c2)nn1-c1ccccc1 +COc1ccc(OC(C)C(=O)N2CCNCC2)c(Cl)c1 +CS(=O)c1ccc(C(=O)OCCn2c(=O)oc3ccccc32)cc1 +Cc1cc(CN(C)C(=O)CCN2CCCCCC2=O)on1 +Cc1ccc(CCNC(=O)NCc2cc(=O)[nH]c3ccccc23)c(C)c1 +CCCCCC(=O)Nc1c(C)n(-c2ccccc2)n(C)c1=O +O=C1COc2ccc(NC(=O)C34CC5CC(CC(C5)C3)C4)cc2N1 +Cc1nnc(SCC(=O)Nc2ccccc2C(C)C)n1N +Oc1ncnc2c1nnn2Cc1ccc(Br)cc1 +O=C(C1CCCO1)N1CCOCC2(CCC(Cn3cccn3)O2)C1 +Cc1cc(C(=O)Nc2c[nH]cc(Br)c2=O)[nH]n1 +N#Cc1cccc(CNC(=O)Nc2ccccc2-n2cccn2)c1 +CCCNC(=O)c1snc(-c2ccc(Cl)cc2)c1N +O=C(NCCCOc1cccnc1)C1Cc2ccccc2CN1 +OCCCn1c(C2CC2)nc2cc(F)c(F)cc21 +CCOCCC(=O)Nc1ccc(C(=O)N2CCOCC2)c(Cl)c1 +CN(C)C(=O)CNS(=O)(=O)c1ccc(-c2ccccc2)cc1 +Cc1cccc(N2CC3(CCN(C(=O)c4cc(C)n[nH]4)C3)CC2=O)c1 +CCOc1c(F)cccc1C(=O)Nc1ccccc1-n1cncn1 +COc1ccc(C(=O)CSc2nc(C)cc(C)c2C#N)cc1 +OCCCNc1nc2nonc2nc1N1CCCCC1 +COc1nc(NC(=O)N2CCC(Nc3ccccc3)C2)n[nH]1 +Cc1ccc(Cc2nn(CCO)c(=O)[nH]c2=O)cc1 +CC(C)NC(=O)Cn1nc2c3ccccc3nc(C3CC3)n2c1=O +Cc1ccc(-c2cc(C(=O)Nc3cccc(C#N)c3)on2)cc1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1ccc(F)cc1 +Cc1c(C(=O)N2CC(C)OC(C)(C)C2)cnn1C +Cn1c(NC(=O)c2ccccc2F)cc(=O)n(C)c1=O +CC(Cc1ccccc1F)C(=O)N1CCN(C(=O)c2ccco2)CC1 +CC(C)(C)CC(C)(C)NC(=O)CS(=O)(=O)c1ccccc1 +Cc1nc(CC(=O)Nc2cc(C(F)(F)F)ccc2Cl)cs1 +Nc1cccc(-c2nnc(COc3ccccc3F)o2)c1 +CC(NC(=O)CNC(=O)c1cc2occc2n1C)c1ccccc1 +CSc1ccc(OC(C)C(=O)N(C)Cc2ccccn2)cc1 +CC(C)C(C)NC(=O)CCNC(=O)c1ccc(Br)cc1 +CCCNS(=O)(=O)c1cc2n(c1)CCCNC2=O +Cc1ccc(CC(=O)NCc2nncn2C)s1 +O=C1CC(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)CN1 +CC(C)Oc1ccc(NC(=O)CCC(=O)N2CCOCC2)cc1 +CC(c1ccc(F)c(F)c1)N(C)C(=O)c1scnc1C1CC1 +CCCn1c(C)nnc1SC(C)C(=O)N(C)C +COc1cc(F)c(NC(=O)NCc2cn3ccsc3n2)cc1F +CN(C(=O)c1cc(F)c(F)c(F)c1)C1CCOCC1 +CCc1noc(CNc2ccc3c4c(cccc24)CC3)n1 +CCn1cc(C(=O)Nc2ccn(-c3ncccc3Cl)n2)cn1 +O=c1cc(C=Cc2ccc(Cl)cc2)ccn1CCCO +CCc1ccc(-c2ccc(C(=O)NCCOC)c(N)n2)cc1 +O=C(CCc1ccc(F)cc1)Oc1cccc(C(=O)NC2CC2)c1 +Cc1ccc(-n2cnc3cc(NCc4ccccn4)ccc32)cc1 +CC(C#N)Cn1c(-c2ccc(N)cc2)nc2ccccc21 +CCNC(=O)NC1(C(=O)NC(C)COc2cccc(C)c2)CCCC1 +COc1cc(N)ccc1NC(=O)CCc1ccc(C)cc1 +CC(NC(=O)c1cccs1)C(=O)N1CC(C)c2ccccc21 +Cc1nc(C2(NS(=O)(=O)c3c(C)nn(C)c3C)CCCC2)no1 +COc1ccc2c(C(=O)NCCC(C)C)cc(=O)oc2c1 +O=C(NC1CC(=O)N(c2ccc(F)cc2)C1)c1cccs1 +Cc1nc2ncnn2c(C)c1CCC(=O)NCCc1ccccc1F +CN(C)C(=O)N1CCCC(C(=O)N2CCN(c3cccnc3)CC2)C1 +NC(=O)c1cnc(NC(=O)C2(c3ccccc3)CCC2)s1 +COC(CNC(=O)CCC(F)(F)F)c1ccc(C)s1 +CCOc1ccc(NC(=O)c2ccsc2)cc1CO +CC(C)c1ccccc1NC(=O)CNC(=O)OC(C)(C)C +Cc1ccc2cccc(OS(=O)(=O)c3cn[nH]c3)c2n1 +Cc1ccc(C(=O)N2CCN(c3nnc(C)c(C)c3C#N)CC2)s1 +Cc1oncc1C(=O)NCCOc1cccc(N)c1 +CC(=O)Nc1cccc(-c2nccn2CC(O)CO)c1 +Cc1ccc(CNC(=O)C2CC(=O)N(C)C2c2ccc(F)cc2)o1 +Cc1nnc(CNC(=O)C2CN(S(C)(=O)=O)C2)o1 +O=C(NCc1cccc(COc2ccccc2)c1)C1CC1 +Cc1ccc(=O)n(CCC(=O)c2ccc(F)cc2)n1 +c1ccc(OCC2CC2)c(NCc2nnc(C3CC3)o2)c1 +Cc1cc(-c2ccc3c(c2)C(C)(C)C(=O)N3C)nc(N)n1 +COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)c1ccc(C)cc1 +COCc1ccccc1NCC(=O)NCc1ccc(C)cc1 +CC(=O)N1CCN(C(=O)Nc2cccc(OC(F)(F)F)c2)C(C)C1 +O=S(CCSc1ncnc2ccsc12)c1ccccc1 +Nc1nc2nc(-c3ccco3)cc(C(F)(F)F)n2n1 +Cc1noc(C)c1CC(=O)Nc1ccc2c(c1)C(=O)N(C)CCO2 +O=c1c(Cl)c(Cl)cnn1Cc1ccc(F)cc1 +CCCOc1cc(C2NC(=O)NC(C)=C2C(=O)OC)ccc1OC +CC(C)Sc1ccccc1C(=O)Nc1cccc(NC(N)=O)c1 +COc1cc2c(cc1CNC(=O)c1cc(C(C)C)nn1C)CCC2 +Cc1ccc(C(=O)NC2CCN(c3ccc(F)cc3)C2=O)cc1F +CCCOc1ccc(C(=O)N2CCNC(=O)C2)cc1OCCC +COCCOc1ccc(NC(=O)N(C)C(C)c2ccccn2)cc1F +Cc1ccc(NCC(=O)N2CCCCCC2)c(C)c1 +CC1CN(CC(=O)N2CCCC2c2cccs2)CCO1 +CC(=O)Nc1ccc(NC(=O)c2cccc(S(C)(=O)=O)c2)cc1 +CN(Cc1cccc2ccccc12)C(=O)c1ccc[nH]1 +O=C(Nc1ccccc1Cl)NC1CCN(c2ccccc2)C1=O +O=C(Nc1c[nH]cc(Br)c1=O)C1CCc2cn[nH]c2C1 +NC(=O)COc1ccc(S(=O)(=O)Nc2ccccc2)cc1 +CC(NC(=O)C1CCC(=O)N1)C1(N2CCOCC2)CCCC1 +O=C(c1cnn2ccccc12)N1CCC(c2cc(=O)[nH]cn2)CC1 +CCOc1ccc(-c2cc(C(=O)N(C)Cc3ccccc3)n[nH]2)cc1 +COCc1cccc(C(=O)Nc2cccnc2-n2cncn2)c1 +O=C(NCC1Cc2cc(F)cc(F)c2O1)c1cccc(F)c1 +CCCn1nnnc1Cn1c(=O)n(CC)c2ccccc21 +COc1ccc(N)cc1S(=O)(=O)NCCC(N)=O +CN(C)C(=O)CNS(=O)(=O)c1ccc(N)cc1 +COCCCC(=O)Nc1ccc(-n2cccn2)cc1C(F)(F)F +CC(C)N(C(=O)c1ccccc1-c1ccc(C(N)=O)o1)C(C)C +CC1CCN(C(=O)c2cnn3c(-c4ccco4)ccnc23)CC1 +Cc1ccc(N2CCn3c(SCC(=O)N4CCCC4)nnc32)cc1 +COc1ccc2nc(SC(C)C(=O)NC3CC3)[nH]c2c1 +COc1ccc(CNc2nc3ccccc3o2)c(OC)c1 +COc1ccc(OC)c(C(O)CCCC(=O)N2CCCC2)c1 +Cc1ccc(C(=O)NC(C)Cn2ccnc2)c(O)c1C +CCc1nn2c(S(=O)(=O)NCc3cccs3)c(C)nc2s1 +O=C(Cc1noc(C2CCCc3[nH]ncc32)n1)NC1CCCC1 +O=S(=O)(NCCC(O)c1ccco1)c1ccc2ccccc2c1 +COCCN(CC(C)C)C(=O)Cc1ccccc1Cl +CCCNC(=O)C1CN(S(=O)(=O)CC)c2ccccc2O1 +CCCCS(=O)(=O)N1CCN(S(C)(=O)=O)CC1 +CCc1ccc(CN(C)C(=O)c2ccc(C(=O)OC)cc2)cc1 +CC(O)(CNS(=O)(=O)Cc1cccc(F)c1)c1ccsc1 +Cc1ccc(C(=O)CC2(O)C(=O)Nc3ccc(F)cc32)c(C)c1 +C#CCOCCOC(=O)Cn1c(=O)sc2ccccc21 +COc1cc(Cl)ccc1C(=O)N1CCN(Cc2ccccn2)CC1 +O=C(Cn1cccn1)N1CCCC1c1nnc2n1CCCCC2 +CCCN(C)C(=O)c1ccc(-c2cccs2)nc1C +CCC(C)NC(=O)C(C)NC(=O)c1cc(C)c(C)s1 +CCc1nnc(NC(=O)C2Cc3ccc(C)cc3C(=O)O2)s1 +Cc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1-n1cnnn1 +CSc1nc(C)c(CCC(=O)Nc2ccc3c(c2)OCO3)c(C)n1 +COc1ccccc1OCCN1CCN(Cc2cnn(C)c2)CC1 +COc1cc(CNC(=O)c2cc(C)no2)ccc1OCC1CCCO1 +CCOc1ncccc1C(=O)NC(C)c1ccc(F)cc1F +CCC(=O)c1ccc(C)c(S(=O)(=O)NC2CCCC2)c1 +CC1CC(NC2CCCc3[nH]c(=O)ccc32)C(=O)N1c1ccccc1 +CCOC(=O)Cn1nc(-c2cccnc2)nc1-c1cccnc1 +CCCc1c(C)nn(C(=O)CCC(=O)Nc2ccccc2)c1C +N#Cc1ccc(S(=O)(=O)Nc2ccccc2Br)cc1 +CC(NC(=O)c1cccnc1)c1ccc(NC(=O)C2CC2)cc1 +O=C(CCCc1ccccn1)Nc1cc(F)c(F)c(F)c1 +CCCNC(=O)c1cccc(C(=O)N(Cc2ccccc2)C2CC2)c1 +Cc1cc(C)n(CCC(=O)Nc2ccc(Cl)cc2N)n1 +OCC(O)Cn1cnc2c(SCc3ccccc3)ncnc21 +CC(C)CNC(=O)N1CCN(c2cnccn2)CC1 +CN(Cc1ccc(O)cc1)C(=O)c1ccc(F)cc1 +CCCc1c(C(=O)OCC)cnc2nc(C(F)(F)F)nn12 +Cc1cc(-c2nn3c(-c4cccc(F)c4)nnc3s2)no1 +Cc1cc(=O)oc2cc(OC(=O)CCC3CCCO3)c(Cl)cc12 +O=C(NCCO)Nc1ccccc1S(=O)(=O)N1CCCCC1 +Cn1nc(-c2cccnc2)c(-c2cccc(F)c2)c1N +Cc1nc(SCC(=O)Nc2ccccn2)n(-c2ccccc2)c1C +CCCC1CN(C(=O)Nc2ccsc2)CCO1 +CCOC(=O)c1sc2nc(C)nc(NC(CC)CO)c2c1C +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1ccc(Cl)cc1Cl +CC(=O)Nc1ccc(CC(=O)Nc2ccccc2O)cc1 +CCC1Oc2ccc(N)nc2N(C(CC)C(=O)OC)C1=O +CN1CCN2CCN(c3ncccc3Cl)CC2C1=O +COc1ccc(CC(C)CN(C)C(=O)NCC(=O)N2CCCC2)cc1 +COc1ccc2[nH]cc(CCNC(=O)COc3cc(C)on3)c2c1 +O=C(NCCCO)c1cc2ccccc2c(=O)s1 +CCCOC(=O)c1ccc(NC(=O)N(CC)CC)cc1 +N#Cc1ccc(OC(F)F)c(NC(=O)c2ccccc2)c1 +N#Cc1ccc(NC(=O)Nc2ccc(Cl)cc2C#N)cc1 +CC(=O)Nc1ccc(Cl)c(NC(=O)C(C)Sc2ccccn2)c1 +Cc1nn(CC(=O)N2CC(C)C(C)(O)C2)c(C)c1Cl +COc1ccc(NC(=O)C(C)OCC(C)C)c(N)c1 +O=C(Cc1cn2ccsc2n1)N1CCN(Cc2ccccc2)CC1 +Cc1cc(C2Cc3cccc(Br)c3C2)[nH]n1 +NS(=O)(=O)c1ccc(CNC(=O)c2cc[nH]n2)cc1 +CN(Cc1ccco1)C(=O)CCn1c(=O)n(C)c2ccccc21 +Cc1ccc(NC(=O)c2nc3ccccc3[nH]2)cc1C +CC(=O)Nc1cccc(C(=O)OC(C)C(=O)c2ccc(F)cc2F)c1 +O=C(CCNS(=O)(=O)c1ccccc1Cl)NC1CC1 +O=C(NC1CCSc2ccccc21)c1cccc(Br)c1 +Cn1nnc2ccc(C(c3ccc(Cl)cc3)n3cncn3)cc21 +NC(=O)C1CCN(C(=O)NCc2ccc(C(F)(F)F)cc2)C1 +c1ccc(CSc2nccnc2-n2cccn2)cc1 +CCc1ccccc1NC(=O)c1cnc(-c2ccco2)nc1N +CN(C(=O)c1ncn(-c2ccccc2)n1)c1cccc2ncccc12 +OCc1nc2ccccc2n1CC(O)c1ccc(OC(F)F)cc1 +O=C(Nc1cccc(C#Cc2ccccc2)c1)c1cnns1 +Cc1cc(C)cc(N(CCC#N)C(=O)CN2CCOCC2C2CC2)c1 +Oc1ccc(C2NCCc3ccc(F)cc32)c(F)c1 +CC(=O)NC(CC(=O)Nc1ncccc1C)c1ccccc1 +CCOC(=O)Cc1csc(Cc2ccc(OC)c(N)c2)n1 +O=C(Cc1ccccc1)N1CCN(S(=O)(=O)c2ccccc2)CC1 +CCC(C)(NC(=O)c1ccccc1Br)C(=O)OC +COCC(=O)Nc1cc(C(=O)N2CCOCC2)cn(C)c1=O +Cc1c(Cl)cccc1S(=O)(=O)NC(C)c1ccncc1 +C#CCOC(=O)CCCC(=O)Nc1cccc2ccccc12 +O=C(NC(C1CCCC1)C(F)(F)F)c1cnc(C2CCCO2)s1 +CCOCCCNC(=O)c1onc(-c2cccc(C)c2)c1N +O=C1CN(c2ccccc2NC(=O)C2CCCC2)CCN1 +COc1ccc(CN2CCN(C(=O)c3ccoc3)CC2)cc1F +CC(Nc1nc2nonc2nc1N1CCCC1)c1nccs1 +CC(=O)N(C)c1ccccc1NC(=O)NCc1ccncc1 +Cc1ccnc2nc(C(=O)Nc3cccc4c3CCCC4)nn12 +Cc1cc(C)n(CCCN(C)c2cc(C3CC3)ncn2)n1 +CCNc1ncnc2sc(C(=O)NCc3ccccc3F)c(C)c12 +COCCCN1C(=O)CCC2CN(C(=O)N3CCOCC3)CCC21 +COc1cc(CCNC(=O)C2CCOCC2)ccc1OC(F)F +CN(Cc1n[nH]c2c1CCCC2)c1nccnc1C#N +O=C(CNc1ccc(F)cc1F)Nc1cccc(F)c1 +O=S(=O)(Cc1ccccc1)NCCCn1cnc2ccccc21 +COc1ccc(CN(C)Cc2cccc(Cl)c2F)cc1O +CCC(Oc1ccccc1)C(=O)Nc1ccc2c(c1)n(C)c(=O)n2C +O=S(=O)(Nn1cnnc1)c1cccc2cccc(Cl)c12 +CCC(C)CNC(=O)CSc1ccc(N)cc1 +Cc1ccc2ncc(CN3CCCN(c4nc(C)ns4)CC3)n2c1 +COc1c(Cl)ccc2c1C(c1ccc[nH]1)NCC2 +COC(=O)c1cccc(NC(=O)CSc2nc(C)cc(C)n2)c1 +COc1cccc(-c2noc(CNc3c(C)cccc3C)n2)c1 +CC(C)CC(=O)NCC1(c2ccc(F)cc2)CCOCC1 +CNC(=O)CNS(=O)(=O)c1ccc(C)cc1Br +COc1cc(F)ccc1NC(=O)c1cccnc1N +COc1coc(C(=O)Nc2cccc(C)n2)cc1=O +CC(=O)NCCNC(=O)c1cc(S(C)(=O)=O)ccc1C +C=CCNS(=O)(=O)c1cc(C(=O)CC)ccc1C +Cc1n[nH]cc1CN1CC(c2ccccc2Cl)OCC1C +CSc1ccccc1NC(=O)C(C)Oc1cccc(C(C)=O)c1 +CCOc1cccc(CS(=O)(=O)c2ncc(CO)n2C)n1 +CCC(=O)c1ccccc1OS(=O)(=O)c1ccc(F)cc1 +O=C(NCCOc1ccc(-c2ccccc2)nn1)c1ccccc1 +c1cc(-c2noc(COc3ccc4c(c3)OCO4)n2)cs1 +NS(=O)(=O)c1ccc(F)c(C(=O)NC2CCOCC2)c1 +CCNC(=O)CN(CC)C(=O)NCc1noc(C(C)(C)C)n1 +CCc1nnnn1Cc1sc2ccccc2c1Cl +COc1ccc(-c2cc(C(=O)N(C)C)c3ccccc3n2)cc1 +CC(NC(=O)Nc1ccccc1N(C)C)c1ccncc1 +NC(=O)c1ccc(CNc2ccc3nnc(C(F)(F)F)n3n2)cc1 +CN(CCc1ccncc1)C(=O)CC(C#N)c1ccccn1 +C=CCN(Cc1cccs1)C(=O)NC(C)C(=O)N1CCCCC1C +COCCn1cc(CC(=O)NCc2cccn2C)c2ccccc21 +Cc1cc(Cl)ccc1NC(=O)Cn1nnn(-c2cccs2)c1=O +Cc1csc(S(=O)(=O)CC(=O)Nc2cc(C(C)(C)C)no2)n1 +CN(CC(N)=O)C(=O)CCc1c(F)cccc1F +Cn1cc(-c2nc(C(=O)OC3CCCC3)cs2)cn1 +COCC(=O)N(C)Cc1cccc(OC(F)(F)F)c1 +CC(C)(O)CN1CCN(C(=O)c2occc2-c2ccccc2)CC1 +CCOC(=O)C1CCCN(S(=O)(=O)N2CC(C)CC(C)C2)C1 +O=C(Cc1ccsc1)NCCNc1cnccn1 +CC(C)CC(NC(N)=O)C(=O)NCc1ccc(F)cc1 +Cc1ccc(C2NCCc3cc(F)c(F)c(F)c32)cn1 +Nc1ccc(C(=O)NCC(=O)N2CCNC(=O)C2)cc1 +NC(=O)C(NC(=O)c1cnns1)c1ccccc1 +CCOc1ccc(C(=O)NC2CCCN(c3ccccc3)C2=O)cc1 +Cc1nn(CC2=NS(=O)(=O)c3ccccc3N2)c(=O)c(C#N)c1C +CC(=O)N1CC(C(=O)Nc2ccccc2O)Oc2ccccc21 +Nc1cc(F)ccc1NS(=O)(=O)c1cccs1 +Cc1ccc(C)c(NCC(=O)NCC2COc3ccccc3O2)c1 +Cc1nc(C)c(C(=O)NC(C#N)c2ccccc2)s1 +CCOC(=O)C1CCN(C(=O)CSc2nncs2)CC1 +CCC1CN(C(C(=O)OC)c2ccc(F)cc2)CCO1 +Cc1n[nH]c2c1C(O)CC(c1ccc(Cl)cc1)C2 +O=C(NCCc1n[nH]c(-c2ccco2)n1)NCc1ccco1 +Cc1nnc2n1CCN(CC(O)COCc1ccc3c(c1)OCO3)C2 +COCc1cccc(C(=O)Nc2c(C)n[nH]c2C)c1 +C=CCNC(=O)c1ccc(NC(=O)N(C)C(C)CC#N)cc1 +O=C(c1ccc(F)c(F)c1)N1CCN(C(=O)c2ccccn2)CC1 +COc1ccc(F)cc1NC(=O)Cc1ccc(-n2cnnn2)cc1 +CC(=O)NCCc1nc2ccccc2n1Cc1ccccc1Cl +Cc1c(NC(=O)c2cccc(C#N)c2)c(=O)n(-c2ccccc2)n1C +CC1CCCC(CNc2cccc(C(=O)N3CCCC(O)C3)c2)C1 +COc1ccc(C(C)NC(=O)CCOC(C)C)cc1Br +Cc1ccc(NC(=O)c2cc(C)n(C3CC3)c2C)cc1S(C)(=O)=O +O=C(NCCC(O)C1CC1)C1(c2ccc(Cl)cc2)CCCC1 +CN1CCCC(=O)c2cc(Br)cc(N)c21 +Cc1ccc2c(=O)c(C(=O)N3CCCC3)c[nH]c2n1 +CCc1nc(CN2CCN(C(=O)Nc3cnn(C)c3)CC2)cs1 +O=c1c(Cl)c(Cl)cnn1CCOc1ccccc1 +CC(C(N)=O)N1CCN(S(=O)(=O)N(C)C2CCCCC2)CC1 +O=C(NC1CCOCC1)C1CN(c2cccc(F)c2)CCO1 +CCc1ccsc1C(=O)Nc1ccccc1C(=O)NC +Cc1nc2cc(NC(=O)C3CC(=O)N(c4cn[nH]c4)C3)ccc2o1 +CCOc1cc(C)ccc1NC(=O)NCC(C)C(=O)OC +CC(C)COc1cccc(CNC(=O)C2CC(=O)N(C(C)C)C2)c1 +Cc1[nH]c2ncnc(NC(=O)c3ccc4c(c3)nnn4C)c2c1C +COc1ccc(C)cc1S(=O)(=O)NC1CCCC1 +O=C(Nc1cccc(CO)c1)c1cc2c(s1)CCC2 +CC(C)c1ccc(-c2cc(CO)nn2CC#N)cc1 +O=C(CCC(=O)N1CCOCC1)NCC(O)c1ccccc1Cl +CNS(=O)(=O)c1cccc(CNc2ncccc2C#N)c1 +CN(Cc1cnn(-c2ccccc2)c1)CC(O)c1ccccc1F +COC(=O)CCCN1CC(C)(C)Oc2cccc(N)c21 +Cc1n[nH]c(C)c1CCC(=O)N1CCOC(CCc2ccccc2)C1 +Cc1cc(-c2csc(NC(=O)COc3ccccc3)n2)c(C)n1C +Cc1nc(-c2ccccc2)n(CC(=O)Nc2ccccc2Cl)n1 +Cc1ccc(NC(=O)c2ccc(CO)cc2)c(F)c1 +CS(=O)(=O)c1c(F)ccc(N2CCOCC2)c1C#N +Cn1nnc2ccc(-c3noc(CNC(=O)c4cccs4)n3)cc21 +Cn1cc(C(=O)NC2(C)Cc3ccccc3C2)ccc1=O +Nc1ccc2c(c1)N(CCOc1ccccc1)CCC2 +Cc1ccncc1NC(=O)NCC(=O)NCCc1ccccc1 +CC(C)(C)n1cc(NCc2cnc3ccc(Br)cn23)cn1 +COCCOc1ccccc1C(=O)NC(C)(C)C#N +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)CCc1cccs1 +COC(=O)c1ccc(C(=O)Nc2cc(F)ccc2OC)o1 +Cc1cc2c(SC(C)C(=O)N3CCNCC3)ncnc2s1 +Cc1nc[nH]c1-c1nccn1CCc1nc2c(s1)CCCC2 +COc1cccc(NC(=O)c2c[nH]c3cc(F)cc(F)c3c2=O)c1 +COC(=O)CCNC(=O)c1nn(CC(C)C)c(=O)c2ccccc12 +CN(C)c1ccc(C(=O)NCc2ccccc2Cl)cc1 +CCOC(=O)C1CCCN(C(=O)NC(C2CC2)C2CC2)C1 +CC(C)CCC(=O)N1CCN(CC(O)C(F)(F)F)CC1 +C1=C(CN2CCOC(c3cccs3)C2)COCC1 +N#CCCn1cc(C(=O)Nc2nccs2)c(-c2ccc(F)cc2)n1 +CC(=O)Nc1ccc(C)cc1NC(=O)CC(O)c1ccc(Cl)cc1 +Cc1cc(CNc2cc(C(C)C)ncn2)cc(C)n1 +Cc1nc(C2CCN(Cc3cccnc3)C2)[nH]c(=O)c1F +Nc1nc(N)c2ncn(-c3ccc(Cl)c(Cl)c3)c2n1 +N#CCCn1ncc2c(NCCc3cccc4cccnc34)ncnc21 +CC(=O)Nc1ccc(O)c(C(=O)OCc2cn3ccccc3c2C#N)c1 +CN(C(=O)C1CC2CCC1O2)C1CCN(C(=O)OC(C)(C)C)CC1 +COCCOC(=O)CN1C(=O)CNc2cc(OC)ccc21 +Cc1cccc(Nc2nccnc2C2CCCN2C(=O)C(C)C)n1 +Cc1ncnc(C)c1C1NCCc2ccc(N)cc21 +COc1ccc2c(c1)cc(C#N)c(=O)n2CC(C)C +CC(C)(CNC(=O)Nc1ccncc1)c1ccc2c(c1)OCO2 +Cc1ccc(-n2c(C)nnc2SCC(=O)N2CCCCC2C)cc1 +COc1cc(CNC(=O)C2CCN(C(=O)N3CCCC3)CC2)ccn1 +Cc1ncc(CNC(=O)NCCCSc2ccccc2)s1 +Cc1ccccc1C(C)NC(=O)Nc1nc(C)c(C)o1 +CC(C)Cc1cc(-c2nccn2Cc2noc(C3CCCO3)n2)n[nH]1 +CC(=O)c1ccc(C(=O)NCCNC(=O)Cc2cccc(F)c2)cc1 +Cc1ccc(NC(=O)N(Cc2ccco2)C2CC2)cc1 +CC(C#N)(NC(=O)COC(=O)Cc1noc2ccccc12)C1CC1 +CCN1CC(C(=O)NCC2(N3CCOCC3)CCCCC2)CC1=O +CC(C)(C)C(=O)CC1(O)C(=O)Nc2cccc(C(F)(F)F)c21 +CCCCCNC(=O)c1ccc(S(C)(=O)=O)cc1 +C=CCOc1ccc(-c2nc(C(=O)NCC)cs2)cc1 +Cc1ccc(C(C)NC(=O)Nc2ccn(-c3ncccc3Cl)n2)o1 +O=C(CSc1n[nH]c(=O)n1CC1CCCO1)NC1CCCC1 +CCNC(=O)NC1(C(=O)NC2CCc3ccccc32)CCCC1 +CC(C)c1cc(C(=O)NCCC(=O)NC2CCCC2)n[nH]1 +Cc1ccc(NC(=O)COc2ccc(-c3cc[nH]n3)c(O)c2)cc1 +Cc1cccc(C(C)C)c1NC(=O)COc1ncnc2sccc12 +COc1ccc(S(=O)(=O)NCc2cn[nH]c2)cc1Cl +CCC(CC)C(=O)NC(C)c1ccc(S(N)(=O)=O)s1 +COc1cccc(CC(=O)Nc2ccc(N3CCNC(=O)C3)nc2)c1 +Cc1ccccc1-n1cc(Cn2ccnc2-c2nccn2C)cn1 +CCCNC(=O)c1ccc(NC(=O)NC(C)CC)cc1Cl +COc1c(C)cnc(CNC(=O)CCn2cccn2)c1C +Cc1ccc(NC(=O)CSc2ncccn2)c(F)c1 +N#Cc1ccsc1NC(=O)CCc1ccccc1F +CCCCc1ccc(NC(=O)c2ccncc2)c(N)c1 +O=C(NCCN1Cc2ccccc2C1=O)NC1CCCCC1 +Cc1n[nH]c(C)c1CCC(=O)NCC1COC2(CCCCC2)O1 +Cc1cc(C)c(-n2c(C)ccc(C#N)c2=O)c(C)c1 +COc1ccc(NC(=O)C2CN(C(=O)c3cc(C)on3)C2)c(OC)c1 +Cc1n[nH]c(C)c1CC(=O)N1CCC(CO)CC1 +CCC1CCCN(C(=O)Cc2ccc(F)c(F)c2)C1 +CCOc1cc(C)c(C)cc1S(=O)(=O)n1ccnc1 +NC(=O)COC(=O)CCC(=O)Nc1nccs1 +O=C1NCC(c2ccncc2)N1c1ccc(F)cc1 +CN(C)c1nc(N2CCOCC2)c(C#N)c(=O)o1 +O=C(COc1ncnc2sccc12)Nc1ccc2ccccc2c1 +COc1ccc(NC(=O)COC(=O)c2ccc(C)nc2)cc1 +Cc1nc(COC(=O)C2CC(=O)N(c3ccccc3)C2)no1 +COc1ccc(C(=O)NC(C)C(=O)N2CCCc3ccccc32)cc1 +CCc1noc(CN(C)Cc2ccc(C(=O)OC)c(F)c2)n1 +CCC(Cn1ccnc1)NC(=O)c1ccc(=O)[nH]c1 +CC(C)N(CCCO)C(=O)c1cccc(C#CC(C)(C)O)c1 +CCOC(=O)N1CCC(NC(=O)NC(C)c2ccccc2C)CC1 +COc1ccc(CN(C)C(=O)CSc2ccccn2)cc1F +O=C1Nc2nc(-c3ccsc3)ccc2C1c1ccccc1 +O=C(NCc1ccc(-c2ccc(Cl)cc2)o1)c1ccccn1 +CCOC(=O)c1cc2c(nc1NC(C)=O)CC(C)(C)OC2 +Cc1nc2ncc3c(=O)n(NC(=O)C(C)C)c(C)cc3n2n1 +CCC(CC)NC(=O)CCC(=O)c1cc(C)sc1C +CNC(CCOC1CC(C)CC(C)(C)C1)C(=O)OC +CC1CN(CCC#N)c2cc(C(C)(C)C)ccc2O1 +COCCOCCCNC(=O)N1CCC(C)CC1C +Cc1cc(C)n2nc(SCCNS(C)(=O)=O)nc2n1 +CCOC(=O)c1cc(C(C)C)sc1NC(=O)COC +O=C(Nc1nncs1)N1CCC(CCO)CC1 +COCc1nn2c(CO)c(-c3cc(F)ccc3F)nc2s1 +O=C(COCC1CCCO1)Nc1nc(-c2ccc(F)cc2)cs1 +Cc1ccccc1C(=O)NC1CCN(c2ccc(F)cc2)C1=O +CC1CN(Cc2ccccc2C#N)CCN1c1ccc2nncn2n1 +O=C(NCc1ccco1)c1ccc(-n2nnc3ccccc3c2=O)cc1 +O=C(NCCC(=O)N1CCc2ccccc21)c1cc2cccnn2n1 +Cc1ccc(S(=O)(=O)N2CCC(c3nc(C(C)(C)C)no3)C2)cc1 +CC(C)n1cc(NCc2cc(C(F)(F)F)ccc2F)cn1 +Cc1cc(C(=O)Nc2sc3c(c2C#N)CCC(C)C3)nn1C +Cc1cc(C)n(-c2ccccc2NCc2ccccn2)n1 +O=C(NCCc1ccccc1F)c1cc(F)cc2cccnc12 +Nc1cccc(-c2csc(CC(=O)Nc3ccccc3F)n2)c1 +Cc1ccc(F)c(NC(=O)CNC(=O)OC(C)(C)C)c1 +Cc1cc(C)cc(N(C)C(=O)c2csc(C)n2)c1 +CCCNC(=O)c1ccc(N(C)S(C)(=O)=O)cc1Cl +COC(=O)C1(C(F)(F)F)CCC=CCN1C(=O)OC(C)(C)C +CCn1nc(C(=O)NCC2CCC(C)(C)CC2)ccc1=O +Cc1nc(NC(=O)c2cnc(C3CC3)nc2N)sc1C +CCCn1cc(S(=O)(=O)NC(C)(C)C)c(N)n1 +COc1ccc(C(O)CNC(=O)NCc2nnc3ccccn23)cc1 +CC(C)CN1CCc2c([nH]c3cc(C(C)(C)C)nn3c2=O)C1 +CC(=O)c1c(C)nn(CC(=O)N2CCC3(CN(C)C(=O)O3)C2)c1C +COC(=O)CC(NC(=O)c1ccccc1)c1cccs1 +C=CCNC(=O)Nc1ccc(NC(=O)CC(C)C)cc1 +Cc1csc(=O)n1CCC(=O)NCc1cscn1 +O=C(c1nnc2n1CCCC2)N1CCC(Cc2ccc(CO)cc2)C1 +COc1nc(O)cc(NC2OC(CO)C(O)C(O)C2O)n1 +CN(C)c1cc(C(=O)Nc2ccccc2OCC2CC2)ccn1 +CS(=O)(=O)N1CC2CN(C(=O)c3ccsc3)CC2C1 +CCc1onc(C)c1NC(=O)C1CCN(C(=O)OC(C)(C)C)C1 +NC(=O)C1CCN(c2ncc(-c3ccco3)c(-c3ccco3)n2)CC1 +O=C(c1ccccc1)c1ccc(CNC(=O)C2CCC2)s1 +COc1cccc(C(=O)N2CCc3ccc(Cl)cc3C2)c1OC +CC(=O)N1CCN(C(=O)Cn2c(=O)c3c(ncn3C)n(C)c2=O)CC1 +Cc1cnc(C(=O)N2CCNCC2C(=O)N2CCCC2)cn1 +N#CCCCN1CCN(C(=O)c2ccc(C(F)(F)F)cc2)CC1 +COCCN(CC(=O)N(C)C)C(=O)c1occc1C +O=C(OCc1ccccc1)N1CCC2(CCC(CO)C2)C1 +Cc1cc(C(=O)N2CCN(Cc3cc(C(N)=O)cs3)CC2)c(C)o1 +COc1ncccc1CNC(=O)Nc1ccccc1OC(F)F +CCNc1ncnc(Nc2cccc(C(=O)OCC)c2)c1N +CCOC(=O)Cn1nc(C)c2c1N=C(O)CC2C1CCCCC1 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1ccco1 +CCOC(=O)c1cccnc1N(CCC#N)C(C)C +CCN(Cc1ccccc1C)C(=O)c1ccc(F)cc1 +O=C(Cc1cccc(NC(=O)c2ccnc3[nH]ccc23)c1)NC1CC1 +CC(NC(=O)c1cccs1)C(=O)NCC(O)c1ccco1 +Fc1cnc(NC2COC3(CCN(c4ccncn4)C3)C2)nc1 +CCCn1nnc(C(=O)OC2CCCCC2)c1N +CCCCCCNC(=O)c1ccc(S(N)(=O)=O)cc1 +O=C(NCc1nnc(-c2cccs2)o1)c1cccc(F)c1F +Cc1cc(F)ccc1CCNC(=O)c1cn(CC(N)=O)nn1 +Cc1cc(C)n2nc(C(=O)NCC(=O)OCc3ccccc3)nc2n1 +CCC(C(=O)N(C)Cc1c(C)nc2sc(C)cn12)N1CCCC1=O +Cc1cnn(CCC(=O)N2CC(C)Sc3ccccc32)c1 +N#Cc1c(-c2ccc(Cl)cc2)nn(CCO)c1N +Cc1nc(CN)nc(COc2ccc(Cl)cc2)n1 +CCC(=O)N1CCC(OCc2ccccn2)C(Cc2ccccc2)C1 +COc1ccc(C(=O)CSc2ccc(N)cc2)cc1 +O=C1CC2C(CCN2S(=O)(=O)c2ccccc2F)N1 +CCN(C(=O)COc1ccc(C(C)=O)cc1)c1cccc(F)c1 +CNC(=O)NC(C)(C)C(=O)NCCc1ccc(F)cc1 +CS(=O)(=O)N1CC(C(=O)Nc2cc3ccccc3oc2=O)C1 +Fc1ccccc1CN1CCN(c2nnnn2-c2ccccc2)CC1 +CCC(=O)N1CCCC(C(=O)Nc2ccc(C#N)cc2)C1 +Cc1nc(C#N)c(C#N)n1Cc1ncnn1CC(C)C +CC(C)CN1CCN(Cc2cscn2)C(C)C1=O +CCOC(=O)CS(=O)(=O)Nc1ccc(NC)cc1 +CC(C)(CNCc1ccc(F)cc1F)N1CCOCC1 +CCNc1ncccc1S(=O)(=O)NC1CCCCC1 +Cc1cc(N(Cc2c(F)cccc2Cl)C2CC2)n2ncnc2n1 +Cn1cc(S(=O)(=O)CC(=O)N2CCOCC2)c2ccccc21 +COc1ncc(-c2ccc3cccc(OC)c3n2)c(OC)n1 +Cc1noc(C)c1CN(C)c1cc(C(C)C)nc2ccnn12 +COc1cccc(NC(=O)COC(=O)CC2CCCCC2)c1 +CCOC(=O)Cn1cnc2sc(CC)cc2c1=O +CCCNC(=O)CNC(=O)Cn1nc(C)c(N)c1C +COc1ccc(OC)c(CNc2ncnc3ccsc23)c1 +CC(NC(=O)C1(C#N)CCCC1)c1cccc(-n2cccn2)c1 +COc1cccc(NC(=O)c2cccc(CC#N)c2)c1 +CCOC1CCC2C1OCCN2C(=O)c1cnc(C)cn1 +Cc1ccc(NC(=O)c2ccncc2)c(Br)c1 +COC(=O)C1=C(C)C(C(=O)N2CCCC(C(F)(F)F)C2)=NC1C +O=C(Nc1ccccc1NCCc1ccccn1)c1ccoc1 +O=C(NCc1cn(-c2ccccc2)nn1)C1CCCC1 +CCCc1sc(C(=O)N2CCCn3ncnc32)cc1CC +Cc1cc(C(=O)Nc2cc(C)nn2CCC#N)[nH]n1 +CCOC(=O)C(c1ccc(N)cc1)N1CCCCC1=O +CCc1noc(CN2CCCc3c(C)ccc(F)c32)n1 +COc1cccc(CC(=O)NCCc2nc(C(C)C)no2)c1 +C#CCN1CCN(S(=O)(=O)c2ccc(C)c(F)c2)CC1 +COCCNC(C)C(=O)c1ccc(OC)c(N)c1 +O=C(NCCNc1ncccn1)c1ccc(F)cc1F +CCN1CCC2(CCCN(S(=O)(=O)Cc3ccccc3)C2)C1=O +Cc1cccc(-n2ccnc(NCCc3ccccc3)c2=O)c1 +Cn1cccc1C(=O)N1CCC(C(=O)N2CCCCCC2)CC1 +OCc1cccc(-c2cc(O)cc(Br)c2)c1 +Cc1noc(C)c1C(C)NC(=O)c1cccc(OCC(N)=O)c1 +CCn1c(=O)n(Cc2cc(=O)n3ccc(C)cc3n2)c2ccccc21 +CCc1ccc2c(c1)S(=O)(=O)N=C(NCc1ccco1)N2 +O=C(c1cc(-c2ccccc2)on1)N1CCC(Nc2ncccn2)CC1 +Cn1ncc2c(=O)n(CC(=O)Nc3cc(C#N)ccc3Cl)cnc21 +CSc1cccc(C(=O)Nc2cc(C)nn2C)c1 +CC(C)(C)NC(=O)CCc1ccc(N2CCCC2)c(N)c1 +COC(=O)c1cc(CNC(=O)c2scnc2C2CC2)ccc1OC +O=C(CC1OCCc2ccccc21)N1CCOCC1C1CC1 +Cc1ccc(C)c(C(=O)NCCNc2cc(-n3cccn3)ncn2)c1 +COc1cc(C2CC(=O)Oc3cc(C)[nH]c(=O)c32)cc2c1OCO2 +COc1ncccc1CNS(=O)(=O)c1cn(C)c(C)n1 +COc1ccc(Cl)cc1CSc1n[nH]c(N)n1 +COc1c(C)cc(Cl)cc1-c1nn2cc(N)nc2s1 +Nc1c(C(=O)N2CCOCC2)sc2nc3c(cc12)CCC3 +CCOC(=O)c1[nH]c(C)c(C(=O)N2CCC(C)CC2)c1C +COc1ccc(C(=O)Nc2cc(-c3cccnc3)no2)cc1 +Cc1ccc(NC(=O)N2CCC(n3cnc4cccnc43)CC2)c(C)c1 +Cc1noc(CCCC(=O)N(C)Cc2ccccc2F)n1 +COc1cccc2cc(C(=O)Nc3cccc4cccnc34)oc12 +Cc1nc(-c2ccc(C(=O)NCc3ccccc3Cl)cc2)no1 +Cc1cc(S(=O)(=O)NCC2CCCO2)ccc1N1CCCC1=O +Cc1sc2c(=O)n(C(C)C)cnc2c1C(=O)Nc1ccc(F)cc1 +O=C(Nc1cccc2cnccc12)OCC(F)(F)F +CN(C)C(=O)CCNC(=O)c1cnc(Cc2ccccc2)s1 +CC(C)(C)Oc1cccc(-c2cc(=O)n3nccc3[nH]2)c1 +O=C(NCc1ccc(-c2nc3ccccc3[nH]2)cc1)c1cnn[nH]1 +CCC1COC(C)CN1CCNc1ccccc1F +CCOc1cc(C(N)c2nc(C)cs2)ccc1OC +CC(C)Cc1cc(C(=O)NCCS(=O)(=O)N2CCCC2)n(C)n1 +Cc1cc(C)n(S(=O)(=O)c2cc(Cl)ccc2Cl)n1 +Cc1nc(CC(=O)Nc2cccc(-n3cnnn3)c2)cs1 +O=C(Cn1c(=O)c2cccn2c2ccc(F)cc21)N1CCOCC1 +Cn1nc2n(c1=O)CCN(Cc1cc(=O)c(O)co1)C2 +Cc1noc(CC2CC3CN(C(=O)c4ccn(C)n4)CC3O2)n1 +CS(=O)(=O)c1cccc(C(=O)Nc2nnc(-c3cccnc3)o2)c1 +CC(CNC(=O)NCc1ccc(-n2cncn2)cc1)c1nccs1 +Cc1ccc(CSc2nnc(C)c(=O)n2N)c(C)c1 +CC(NC(=O)NCCOc1ccc(F)cc1F)c1ccncc1 +CCC(CC)NC(=O)c1cccc(N(C)S(C)(=O)=O)c1C +COc1ccc(Oc2cc(CNC(=O)NC3CC3)ccn2)cc1 +CN(CCNS(C)(=O)=O)C(=O)Cc1cccc(Br)c1 +Cc1nn(C)c(C)c1CC(=O)Oc1ccc2ccc(=O)oc2c1 +CCC(C)C(=O)Nc1nc(-c2ccc3c(c2)OCO3)cs1 +Cc1nc(N)nc(C)c1CC(=O)N1CCC(c2ccncc2)CC1 +COCc1c(C#N)nnn1-c1cccc(NC(C)=O)c1 +CC(C)N(Cc1cccc(Cl)c1)C(=O)c1cc[nH]n1 +COC(=O)CC(C)NC(=O)c1oc2c(OC)cccc2c1C +N#CCn1ccnc1-c1cc(Cl)cc(Cl)c1 +CC(C)(C)OC(=O)N1CCCC(CO)(CCO)C1 +O=C(CSc1nnc(Cc2ccccc2)o1)Nc1nncs1 +O=C(NCCc1nnc2n1CCC2)c1ccc(Cl)cc1 +Clc1ccc(Cn2nnc(-c3cccnc3)n2)c(Cl)c1 +CC1CCC(NS(=O)(=O)CC(=O)Nc2ccccc2F)CC1 +CCOC(=O)NCCC(=O)Nc1ccc(C(C)=O)c(C)c1 +CCOC(=O)Cn1nc(C)n2c(cc3sccc32)c1=O +Nc1c(Cl)cc2c(c1Cl)NC(=O)C(c1ccccc1)O2 +COc1cccc(CN(C)C(=O)CN(C)c2ncnc3[nH]cnc23)c1 +Fc1ccc(-n2nccc2-c2ccc(N3CCOCC3)cc2)cc1 +CCNC(C)(C(=O)OC)c1ccc(F)c(Br)c1 +O=C(Nc1cccc(COc2cccc(F)c2)c1)N1CCOCC1 +CC(Sc1ccccn1)C(=O)NCC1CCOC1C(C)C +CN(C)C(=O)Cn1cc(C(=O)N(C)c2ccc3ccccc3c2)nn1 +O=C(NCCC1=CCCCC1)c1ccc(CSc2ncn[nH]2)o1 +Cc1nc(C)c(C(=O)NC2CCCc3c2cnn3C)o1 +CC(C)Cc1cc(NC(=O)c2ccnn2C)n(C)n1 +Cn1cc(COC(=O)CNC(=O)CC(C)(C)C)cn1 +CCCc1nc(CSc2nnc(NC3CC3)s2)cs1 +Cn1ncc2c(N3CCN(c4ccc(F)cc4)CC3)ncnc21 +FC(F)(Br)n1ccnc1-c1ccccc1 +O=C(Nc1ccncc1)c1cnn(-c2ccccc2Cl)c1 +COc1cc2nc(C(C)=O)n(CCC#N)c2cc1OC +CCc1nsc(NC2CCCN(C(N)=O)C2)n1 +Cc1ccc(C(C)NC(=O)C2CC(=O)N(C)C2c2cccnc2)cc1 +O=C(c1ccc[nH]c1=O)N1CCN(C2CC2)CC1c1ccccc1 +Cc1noc(C)c1CN1CCC(O)C1Cc1ccccc1 +COC(=O)C1c2ccsc2CCN1S(C)(=O)=O +CN(C)C(=O)C(Cc1ccccc1)NC(=O)c1ccc(O)c(Cl)c1 +Cc1cc(O)ccc1C1NCCc2c(Cl)cc(O)cc21 +CCOc1ccc(S(=O)(=O)Nc2ccc(Cl)cn2)cc1C +COC(=O)N1CCC(Nc2cccc(F)c2C(C)=O)C1 +CCCN(CC1CCCCO1)C(=O)c1c[nH]c2cccc(F)c12 +O=C(COc1ccccc1F)NCC(O)(c1ccco1)C1CC1 +Fc1ccccc1Nc1c2c(nc3ncnn13)CCC2 +Cc1ccc(CNC(=O)c2cc3cn(C(C)C)cc3s2)o1 +COc1ccc(C(=O)NCC(O)c2ccc(C)o2)cc1 +Cn1c(CCNC(=O)c2cnc3ccsc3c2)nc2ccccc21 +Cc1nn(C)cc1S(=O)(=O)n1nc(C)c(Br)c1C +Cc1ccc2c(c1)-n1nc(C(F)(F)F)nc1CN2 +Cc1nc(C(=O)OC(C)C(=O)N(C)C)nn1-c1ccc(F)cc1 +COc1ccc(NC(=O)CC2CC3CCC2C3)cc1OC +O=C(CSc1nc2ncccc2n2cccc12)NCc1cccnc1 +Cc1ccc2[nH]c(=O)c(CN(C)C(=O)c3cccnc3)cc2c1 +CCc1c(C)nc2ncnn2c1Nc1ccc2c(c1)OCCO2 +Cc1ccc(C(N)=O)cc1NC(=O)c1cccc(F)c1 +CCS(=O)(=O)c1ccc(NC(=O)COc2ccccc2C#N)cc1 +CCNC(=O)c1cc2sccc2n1Cc1cc(OC)cc(OC)c1 +CC(C)C(CNC(=O)COc1ccccc1)N1CCOCC1 +CNC(=O)NCC(=O)Nc1ccc(Oc2ccc(C)cc2)nc1 +CC(=O)NC1CCCN(C(=O)c2ccc(N3CCNC3=O)cc2)C1 +O=C(Nc1cccc(-c2ccsc2)c1)N1CCCC(O)C1 +C=CCSc1ccccc1NC(=O)CSc1nc(C)cc(N)n1 +COc1ccc(CN(C)C(=O)c2cc(C)on2)c(OC)c1 +COc1ccc(Cl)cc1C(=O)NCc1cn2c(C)csc2n1 +CC(=O)Nc1ccc(O)c(C(=O)NCC2CCC(C)CC2)c1 +Cc1cccc(OCC(=O)OCC2CC(=O)N(C3CC3)C2)c1 +Cc1cccc(OCC(C)NC(=O)c2cnc3sccn3c2=O)c1 +CC(=O)Nc1ccsc1C(=O)N(C)CC1(CO)CCC1 +CCOC(=O)c1cc(CNC(=O)c2c(C)oc3c2CCCC3)c(C)o1 +Cc1ccc2[nH]c(C(=O)N3CCN(C)CC3)cc2c1 +Cc1ccccc1S(=O)(=O)C(C)C(=O)NC(C)c1ccccc1 +CC(CC#N)N(C)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +CC(C)NC(=O)CSc1nnc2n1CCN2c1ccccc1 +CC1CCCN(c2ncnc(Oc3ccccc3F)c2N)C1 +Cc1nn(C)c2[nH]nc(NC(=O)c3cn(C)nc3C(C)(C)C)c12 +Cc1cc(C)n(C(=O)CCCOc2ccccc2C)n1 +COc1ccc(Br)c(C(O)Cc2ccsc2)c1 +Cc1ccc(CNC(=O)Nc2cccc(C#N)c2)c(N(C)C)c1 +CCn1c(SCC(=O)N2CCC(C)CC2)nc2ccccc21 +CC(NS(=O)(=O)c1cccnc1)c1ccc(F)c(Cl)c1 +CC(O)CN(C)S(=O)(=O)c1c(N)nc2ccccn12 +CN(C)c1nc(N)nc(COc2ccc(Cl)cc2Cl)n1 +Cc1cc(C(=O)CN2CCOC(c3ccccc3)C2)c(C)n1C1CC1 +CC(O)CNC(=O)C(N)c1c(F)cc(F)cc1F +COC1CCC(c2cccc3cccnc23)n2nc(N)nc21 +Cc1c(C(=O)N(C)C2(C#N)CCC2)cnn1-c1cccc(Cl)c1 +COCCn1ccc(NC(=O)Nc2cccc(C#N)c2)n1 +CC(CNCc1ncnn1C)c1cccc(Br)c1 +CCc1cnc(CN(C)C(=O)NCc2c(CC)noc2CC)s1 +COCCN1CCN(Cc2nc3cc(F)ccc3o2)CC1=O +Cc1c(C(=O)NC(C)c2ccncc2)sc2ccccc12 +COc1ccccc1C(=O)Nc1c(C)cccc1C +N#Cc1cc2ccccc2nc1N1CCOC(c2ccccc2)C1 +CCOC(=O)C=C(N)C1CCN(C(=O)OC(C)(C)C)CC1 +CC(C)COc1ccccc1NCC(=O)NC1CC1 +CCOCC(=O)N(CC(N)=O)Cc1ccccc1 +COc1ccc(C)cc1NCC(=O)Nc1ccnn1C1CCCC1 +Cc1nc(C)c(C(=O)Nc2ccccc2Br)s1 +CC1CC(NC(=O)Cc2csc(NC(=O)C3CC3)n2)CC(C)(C)C1 +CNC(=O)C1CCN(c2nc3ccccc3o2)CC1 +CC(C)CC(C#N)NC(=O)Cc1c[nH]c2ccccc12 +O=C(NCc1ccc(F)cc1)c1ccc(Cn2cc(Cl)cn2)cc1 +CCOc1cccc(CCC(=O)N2CCc3cc(N)ccc32)c1 +CCc1n[nH]c(SCC(=O)Nc2ccc(Cl)cc2Cl)n1 +Cc1ccc(OCC#CCNC(=O)c2ccc3c(c2)OCO3)cn1 +C#CCNC(=O)N1CC(C)OC(c2ccc(F)cc2)C1 +Cc1ccn2c(=NC(=O)c3cnc4ccc(C)cn34)[nH]nc2c1 +C#Cc1cccc(N(CC(=O)N2CCOCC2)C(=O)CC(C)(C)C)c1 +CCOC(=O)c1sc(NC(=O)CCC2CCCO2)cc1C +COc1ccc2cc(C(=O)NCCc3ccsc3)[nH]c2c1 +COC(=O)Nc1ccc(OC(C)C(=O)N(C)c2ccccc2)cc1 +Cc1csc(=O)n1CCC(=O)N1CCN(Cc2ccncc2)CC1 +Cc1cc(S(=O)(=O)N2CC(O)C2)ccc1OC(C)C +Nc1cc(Cl)cnc1Nc1ccc(S(N)(=O)=O)cc1 +NC(=O)c1ccc(COC(=O)CNC(=O)c2ccco2)cc1 +CCN(CC(C)C#N)S(=O)(=O)c1ccc(Cl)cc1F +O=C(Nc1nc2ccc(F)cn2n1)c1ccc(Cl)c2cccnc12 +COC(=O)C1CCCCN1C(=O)c1c(C)n[nH]c1C +CNC(=O)COC(=O)c1snc(-c2ccccc2)c1N +Cn1ncc(C#N)c1NCc1c(F)cccc1Cl +O=C(CNC(=O)C1(c2ccccc2)CC1)Nc1ccc(F)c(F)c1F +CCNC(=O)CN(C)C(=O)C1(c2ccc(F)cc2)CC1 +CNCC1NCCc2ccc(Br)cc21 +O=C(Cn1nnc2ccccc2c1=O)NCC(=O)NC1CC1 +CCC(C)NC(=O)NCc1ccc(OC(F)F)cc1 +Cc1ccc(OCC(=O)Nc2c(C(C)C)cccc2C(C)C)cn1 +O=C(c1ccsc1)N(CCc1cccs1)Cc1ccco1 +COc1ccc(CNC(=O)CCn2ncc3cc(Cl)ccc32)cc1 +Cn1c(=O)c2cc(C(=O)N3CCCCCC3)sc2n(C)c1=O +CCOC(=O)C=C(C)NC(=O)c1ccccc1OC(C)=O +Cc1cc(C(=O)NCc2ncn(C)n2)nn1C(C)(C)C +CN(Cc1nccn1C(F)F)C(=O)CN1CCCS1(=O)=O +CCN(C(=O)CCc1ccc(OC)c(F)c1)C(C)c1ccncc1 +Cc1ccc2oc(C(=O)Nc3ccccc3S(C)(=O)=O)cc2c1 +COc1cc2c(cc1OC)C(NC(=O)c1ccc(C)cc1)CC2=O +COc1ccc(C(O)CNc2ccc(C#N)cc2)cc1F +Cc1csc(CNc2cnn(-c3ccccc3S(C)(=O)=O)c2)n1 +COC(=O)c1c(C)[nH]c(C(=O)N2CCN(C(=O)C3CC3)CC2)c1C +Cc1ccsc1CNC(=O)CCc1c(C)noc1C +Fc1cc(NC2CCCCC2)ccc1-n1cncn1 +COc1ccc(C(O)C(=O)Nc2ccc(F)c(Cl)c2)cc1 +COc1ccc(C(=O)Nc2nccn(C)c2=O)cc1 +Cc1ccc(-n2nnc(C(=O)Nc3cc(C)ccc3C)c2N)cc1 +CC(C)NC(=O)Nc1ccc(CNC(=O)NC2CC2)cc1 +Cc1ccc(F)cc1C(=O)Nc1ccc(C(=O)NC(C)C)cc1 +CCOc1ccc(-c2c3c(nc4nc(N)nc(N)c24)CCCC3=O)cc1 +Cc1cc(C)cc(NCC(=O)N2CCCC(C)C2)c1 +Cc1ccc(CCC(C)(C#N)N2CCOCC2)cc1 +CC(C)(NC(=O)Cc1csc(-c2nc[nH]n2)n1)c1cccc(F)c1 +O=S(=O)(Cc1ccccc1)Nc1ccc(Cc2ccncc2)cc1 +Cc1nn(C)c2nc(N(Cc3cccc(O)c3)C3CC3)sc12 +O=C(Nc1cccnc1)c1cc(=O)c(OCc2ccccc2)c[nH]1 +COc1ccccc1C(=O)NCC(=O)N(C)Cc1cccc(F)c1 +CCNC(=O)NC1(C(=O)Nc2ccc(N3CCCC3)nc2)CCCC1 +CCN1CCN(C(=O)c2c(-c3ccccc3Cl)noc2C)CC1 +COC(=O)CN(C)C(=O)NC12CC3CC(CC(C3)C1)C2 +C#CCNC(=O)c1ccccc1NC(=O)c1ccc(=O)n(C)n1 +O=C(Cn1cnnn1)Nc1ccc(F)cc1OCC(F)(F)F +COCCC(C)NC(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +O=C(CC1NC(=O)c2ccccc21)Nc1ccc(Cn2cncn2)cc1 +COCCNC(=O)c1ccccc1-n1nnnc1C +Cc1[nH]c2cc(C(F)(F)F)ccc2c(=O)c1CN1CCOCC1 +CCn1nc(C)cc1C(=O)Nc1ccc2c(c1)oc(=O)n2C +O=c1oc2ccccc2n1CCN1CCc2ccccc21 +Cc1cccc(OCC(O)CNC(=O)c2cnns2)c1 +Cc1csc(C2CCCCN2C(=O)CCCc2ccccn2)n1 +CN(C(=O)COc1ncnc2sccc12)c1ccccc1 +c1cncc(CN2CC(c3nc(-c4cnccn4)no3)C2)c1 +CC1CN(c2oc(-c3cccs3)nc2C#N)CC(C)O1 +CCCNC(=O)c1cc(S(C)(=O)=O)ccc1Cl +C=CCN(Cc1cccs1)C(=O)c1ccc(COC)o1 +Cc1cc(OCC(=O)Nc2ccccc2)nc(N2CCCCC2)n1 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)CCc1ccc(C#N)cc1 +O=C(CC1CCCO1)NCCNC(=O)c1ccccc1 +Cn1c(=O)c2ccccc2n(CC(=O)NC2CCCCC2)c1=O +CC1CN(C(=O)NCc2ccc(Cn3cncn3)cc2)CC(C)O1 +CCCNC(=O)C(C)Oc1ccc(SC)cc1 +COCCOCCC(=O)N1CCCc2c(C)ccc(OC)c21 +O=C(Cc1cccc2ccccc12)NCc1ccsc1 +CCn1nc(C)c(S(=O)(=O)NCC(=O)N(C)C)c1C +OCC(Cc1cccc(O)c1)C(CO)Cc1cccc(O)c1 +O=C(CCC1(Cc2ccsc2)CCC(=O)N1)NCc1ccccc1 +Cn1c(C(=O)NCc2nc3ccccc3[nH]2)cc2occc21 +Cc1ccc(C2COCCN2Cc2cccc3cn[nH]c23)o1 +CCc1ccc(C(=O)NCC(=O)NCc2ccco2)cc1 +CCCN(CC(=O)OCC)C(=O)c1csc2c1CCC(C)C2 +Cc1cc(=O)oc2cc(OC(=O)c3ccco3)ccc12 +Cc1ccccc1CCNC(=O)C(C)Nc1cnn(C)c1 +CC(=O)Nc1ccc(F)c(C(=O)N=c2sccn2C)c1 +NC(=O)CN(Cc1ccccc1)Cc1ccccc1F +CC(=O)N1CCN(C(=O)c2cc(C)n(Cc3ccccn3)c2C)CC1 +CCN1CCN(CCOc2ccccc2F)C(=O)C1=O +Nc1c(-c2cccnc2)noc1C(=O)NCc1ccccn1 +CC(C)(CNC(=O)CNS(C)(=O)=O)c1ccncc1 +O=C(c1cccnc1)N1CCCc2cc(Cl)ccc21 +CCOC(=O)C1CCCN1S(=O)(=O)c1ccc2ccccc2c1 +COc1ccc(-c2nc3cccc(C)n3n2)cc1OC +C=CCNC(=O)c1ccc(S(=O)(=O)NCC=C)cc1 +Cc1ccc(C)c(Cn2c(CO)nc3ccccc32)c1 +COc1ccc2nc(NC(=O)CSc3ncn[nH]3)sc2c1 +Cc1ccc2ncc(C(=O)NCc3sc(C)nc3C)n2c1 +CC(C)Cc1ncc(CNC(=O)NCc2ncn(C)n2)s1 +CC1(C)CC(=O)c2cc(C(=O)Nc3c(F)cccc3F)c(=O)[nH]c2C1 +COC1CCN(C(=O)c2ccc(O)c(Cl)c2)CC1 +Cc1nn(C)c(C)c1CC(=O)OCCCn1nc2ccccn2c1=O +Cc1cc(C)c(S(=O)(=O)NCCC(=O)NCC(C)C)c(C)c1 +Cc1cc(C)c2c(OCC(=O)Nc3cccn(C)c3=O)nn(C)c2n1 +CCc1onc(C)c1NC(=O)C(c1cccc(F)c1)N1CCOCC1 +O=C(NCCC(=O)c1ccc(F)cc1)NCCN1CCOCC1 +CNC(=O)c1ccc(Cl)c(NC(=O)c2ccc(OC)cc2)c1 +COc1ccc(S(=O)(=O)n2nc(O)cc2N)cc1 +CC(=O)Nc1ccc(NC(=O)c2ccc(-n3cnnc3)cc2)cc1 +O=C(COc1ccc2ccc(=O)oc2c1)NC1CCCCC1 +CNC(=O)NCC(=O)Nc1ccc(C)c(C(F)(F)F)c1 +COC(=O)c1ccc(NC(=O)c2nccc3cc(N)ccc23)cc1 +CC1(C)COc2cc(NC(=O)c3ccccc3F)ccc2NC1=O +CCCC1CN(C(=O)Nc2ccc3nn(C(C)C)cc3c2)CCO1 +CC(C)(C)n1c(NC(=O)C2CC2)nc2ccccc21 +CC(C)(C)OC(=O)N1CCC(NC(=O)C(C)(C)C)CC1 +CN(C1CC1)S(=O)(=O)c1cn(C)c(=O)n(C)c1=O +CN(C)C(=O)N1CCN(C(=O)Nc2c(F)cccc2F)CC1 +Cc1ccc(C(C)NS(=O)(=O)c2cn[nH]c2C)cc1 +Cc1c(C(=O)NCc2cc3ccccn3n2)cnn1-c1ccccc1 +CC(=O)Nc1ccccc1OCc1nc(N)nc(N(C)C)n1 +CC(C)c1nn(-c2ccccc2)cc1CN1CCNC(=O)C1(C)C +Cc1nc(C(C)C)[nH]c(=O)c1C(=O)N1CC2CCCC2C1 +COC(CCc1ccc2[nH]c(=O)oc2c1)(OC)OC +Cc1cccc(NC(=O)CC2CSc3nc(C)c(C)c(=O)n32)n1 +CN(C)S(=O)(=O)N1CCc2[nH]nc(-c3ccc(Cl)cc3)c2C1 +CCc1n[nH]c(C2CN(C(=O)c3ccc(S(C)=O)cc3)CCO2)n1 +CCOC(=O)C=C(c1cc(C)[nH]c1C)N(CC)CC +Cn1cc(C(=O)Nc2ccccc2NC(=O)c2cccs2)cn1 +CC(=O)NCCNC(=O)CNC(=O)c1ccc(Cl)cc1Cl +CN(Cc1ncc(-c2ccccc2)o1)S(=O)(=O)c1cccs1 +COc1ccc(-c2noc(CC(NC(N)=O)c3cccs3)n2)cc1 +Nc1ccc2oc(CC(=O)N3CCCc4ccccc43)nc2c1 +COc1cccc(-c2noc(C3CCN(S(C)(=O)=O)CC3)n2)c1 +COc1cc2c(c(Br)c1O)C(CO)NCC2 +CC1CCN(c2cc(NC(=O)NC(C)(C)C)ncn2)CC1 +CC(Cc1ccco1)NC(=O)N1CCCC(c2nncn2C)C1 +Cc1ccc(C)c(NC(=O)Nc2ncccc2C)c1 +CCC(=O)c1ccc(OC(=O)CCc2cnn(C)c2)cc1 +CN(C(=O)CCc1nc(C2CC2)no1)c1cc(C#N)c2ccccc2n1 +CC(C)OCC(O)CN1CCN(CC(=O)N2CCCCC2C)CC1 +CCC(C)n1cc(O)c(=O)cc1CN1CC(C)OC(C)C1 +CCN(CC1CCCO1)C(=O)Cc1c[nH]c2ccccc12 +CCCn1nc(-c2ccc(OC)cc2)cc(C(C)=O)c1=O +NC(=O)N1CCCC(C(=O)NCCc2cccc(Cl)c2)C1 +O=C(Nc1cccc(-c2cn[nH]c2)c1)c1ccc(N2CCCC2=O)cc1 +CCN(C(=O)CN1C(=O)CSc2ccccc21)c1cccc(F)c1 +CCN1C(=O)CCC12CCC(NC(=O)c1ccsc1)CC2 +CCCC(C(=O)Nc1nncs1)c1ccccc1 +CC1CN(S(=O)(=O)N2CCN(c3cnccn3)CC2)CC(C)O1 +CCN(C)c1ccccc1NC(=O)N(C)CC(C)C(=O)NC +CNc1ncnc(NCc2ccc(Cl)cc2)c1N +Cc1cc(C)nc(SCC(=O)NC2CCN(CC(F)(F)F)C2)n1 +CCCNC(=O)CCNC(=O)c1cc(NC(C)=O)ccc1F +CCC(=O)N1CCCN(C(=O)C(C)NC(C)=O)CC1 +CC(=O)N(CCc1ccccc1)CC(=O)NCc1ccc(=O)[nH]c1 +O=C(c1ccc(Cn2cccn2)cc1)N1CCc2ccccc21 +Cc1nc(CN2CCN(c3ccc4ccc(F)cc4n3)CC2)cs1 +Cc1ccc(NC(=O)N2CC(C)CCC2C)cc1N1CCOC1=O +Cn1c2c(c(=O)[nH]c1=O)C(C(F)(F)F)(C(F)(F)F)NC(=O)N2 +CCC(C)NC(=O)N(C)Cc1cccc(OC)c1 +CCS(=O)(=O)NCCN1CCCc2ccccc21 +CCN(Cc1cccc(C)c1)C(=O)Cc1cc2ccccc2[nH]c1=O +Cc1cc(CN2CCCC2C(=O)OCc2ccccc2)no1 +CC1CCCCC1NC(=O)C1CCCN(C(=O)N(C)C)C1 +CN(C1CCCCC1)S(=O)(=O)N1CCCN(C(N)=O)CC1 +CC(C)c1n[nH]c(C2CN(CCNS(C)(=O)=O)CCO2)n1 +Cc1ccc(=O)n(C(C)C(=O)N(C)C2CCCCC2)n1 +O=C(NCCC1COc2ccccc2O1)Nc1nc[nH]n1 +O=C(c1cc(Br)c[nH]1)N1CCCCC1 +CCCS(=O)(=O)c1ccc(C)cc1CC(=O)OC(C)C +COC(=O)c1ccc(NC(=O)C2(C)Cc3ccccc3C(=O)O2)cc1 +Cc1nc(C(C)(C)NC(=O)c2cnn(-c3ccccc3)c2)sc1C +O=C(CN1C(=O)Cc2ccccc21)NC1CCCCC1 +Cc1cnc2c(S(=O)(=O)Oc3c(C)nn(C)c3C)cccc2c1 +Cn1cnnc1SCCC(=O)N1CCCCC1 +Cc1n[nH]cc1NC(=O)CNC(=O)c1ccccc1 +Nc1cnc2nc(Cc3ccc(Cl)cc3)[nH]c2c1 +N#CC(C(=O)c1cc2ccccc2s1)c1nnc2n1CCCCC2 +CCOc1ccc(NC(=O)c2ccc(CNC(C)=O)cc2)c(C)c1 +Cc1cc2oc(=O)cc(C)c2cc1NC(=O)c1ccc[nH]1 +CC(NS(C)(=O)=O)C(=O)NC1CCCNC1=O +N#CC(C(=O)CSc1ccc(F)c(F)c1)c1nc2ccccc2[nH]1 +CCC(CC)C(=O)Nc1cccc(C(=O)NC2CC2)c1 +c1csc(-c2ncc(CN3CCC(n4cncn4)CC3)s2)c1 +CCCC(=O)Nc1ccc(C(=O)Nc2ccc(Cl)cn2)cc1 +O=S(=O)(NCC1(c2cccs2)CCOCC1)C1CC1 +COC(=O)C1c2ccsc2CCN1C(=O)C1CC(=O)N(C)C1 +C=CCNC(=O)CN1CCN(c2ccc(Cl)cc2)C1=O +Cc1cc(N)cc2c(CC(=O)Nc3nccs3)noc12 +COc1ccc2ccc(OCc3nc(C(=O)NCCO)co3)cc2c1 +O=S(=O)(c1cccs1)N1CCN(C2CC2)CC1c1ccccc1 +Cn1cc(C(=O)Nc2ccc(Oc3ccccc3)cc2)ccc1=O +CN(Cc1ccc(F)cc1)C(=O)c1ccnc2ccccc12 +Cc1ccc(S(=O)(=O)NC(C)CN2CCOCC2)cc1F +O=C(NCCCn1cncn1)NCC1(c2ccccc2)CC1 +CCOC(=O)C1CCN(C(=O)NC2CCc3ccccc32)CC1 +O=C(NC1CCC(O)CC1)c1cc(Br)c[nH]1 +CCc1noc(CN(C)Cc2cc(F)cc(F)c2)n1 +COc1ccc2[nH]cc(CCNC(=O)c3n[nH]c4c3CCC4)c2c1 +CCOC(=O)C(CC)n1c(CO)nc2ccccc21 +Cc1ccc2cccc(C(=O)Nc3ccn(C)n3)c2n1 +CC(CC#N)N(C)C(=O)Nc1cc(C(C)(C)C)nn1C(C)(C)C +CCc1onc(C)c1NC(=O)N(C)CCOc1cccc(C)c1 +COc1ccnc(N2CCN(CC(O)COc3ccccc3)CC2)n1 +CCCCC1CCC(C(=O)NCc2ccncc2)CC1 +O=c1[nH]c2ccccc2nc1CN1CCN(c2nccs2)CC1 +O=C(CCc1ccc(Cl)cc1Cl)N1CC(O)C1 +CCOC(=O)c1ccc(NC(=O)NC(C)(C)CO)cc1 +COCCC1(CO)CCCN(C(=O)c2ccc(N3CCCC3)cc2)C1 +c1ccc(CN2CCOCC2c2nccc(NCC3CC3)n2)nc1 +CCC(C(=O)OC)n1c(=O)oc2cc(CO)ccc21 +CCC(CC)(CC)NC(=O)n1nc(C)n(N)c1=O +O=C(Cc1noc2ccccc12)NCCOc1ccc2c(c1)OCO2 +Cc1ccsc1C(O)C1COc2ccccc2O1 +Cc1nc(-c2cn(C)c(=O)[nH]c2=O)n(-c2cccc(Cl)c2)n1 +c1cc(CN2CCOC3C(COCc4nccs4)CCC32)ccn1 +COCCNC(=O)c1cc2cnc3[nH]ccc3c2s1 +CCC(NC(=O)C1CCC(=O)N1)c1ccc(C)cc1 +CCCOc1cc2c(cc1OC)C(c1ncccn1)NCC2 +O=C(NC1(c2ccccc2)CCC1)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCc1ccc2c(CSc3nc(CC)n[nH]3)cc(=O)oc2c1 +O=C(Nc1ccccc1Cc1nc(-c2ccco2)no1)c1ccno1 +O=C(NCCCn1ncccc1=O)c1cc(-c2ccc(F)cc2)n[nH]1 +O=C(Cc1cn2ccsc2n1)Nc1ccc(Cl)cc1 +CN(c1cccnn1)C1CCN(C(=O)Nc2ccccc2)CC1 +CC(C)(C)OC(=O)NCc1cccc(C(F)(F)F)c1 +Cn1ncnc1CNC(=O)NCC1(Cc2ccccc2)CCC1 +CC(C)c1cc(C(=O)NCC(=O)C(C)(C)C)no1 +Cn1cc(CNC(=O)Cc2csc(-c3ccccn3)n2)cn1 +O=C(NC(c1nccs1)C1CC1)N1CCc2c(F)ccc(F)c2C1 +O=c1[nH]c2ccccc2nc1CSc1ncccn1 +COCc1nc(N2CCOCC2)ncc1C(=O)NC1CCCCC1 +COc1ccc2c(C)c(-c3nc(-c4ccc(C)nn4)no3)oc2c1 +COc1ccc(NC(=O)CCCn2c(C)csc2=O)cc1Cl +N#Cc1ccc(NC(=O)Cc2ccccc2F)cc1 +O=C(Cc1nnc(-c2ccccc2)o1)NCc1ccncc1 +CSc1ccc(OC(=O)c2cscn2)cc1 +CCOc1ncccc1C(=O)N1C2CCC1CC(=O)NC2 +CC(NC(=O)COC(=O)c1ccc(F)cc1)c1ccccc1 +CSc1nc2ncn(CC3CCCO3)c(=O)c2s1 +O=C1COc2ccc(C(=O)OCCCc3cccnc3)cc2N1 +CCc1nnc(NC(=O)CN(C)C(=O)c2ccco2)s1 +Cc1cc(C(=O)N(C)C(C)c2cccs2)ccc1N +CC(=O)NC(CC(=O)NCCC(C)C)c1ccccc1 +COc1ccc(Cn2c(=O)oc3cc(N)ccc32)cc1C(C)C +Cc1oc2ncnc(NCC(C)(C)c3ccncc3)c2c1C +O=C(c1ccc(Br)c(F)c1)N1CCCC1 +Cc1ccccc1NC(=O)Oc1ccc2c(c1)ncn2C +O=C(CCc1ccc(Br)cc1)NC1(CO)CCCC1 +COc1ccc(S(=O)(=O)NC2CC2)cc1NC(=O)C(C)(C)C +Cc1nnc(NC(=O)NC2CCCN(c3ncccn3)C2)s1 +COc1ccc(CNC(=O)c2ccc(=O)n(C)c2)cc1C +O=C1CCC(C(=O)Nc2ccc(OCCc3ccncc3)cc2)N1 +O=C(Nc1nc[nH]n1)c1ccc(F)c(C(F)(F)F)c1 +COC(=O)CCn1c(-c2cccc(F)c2)nc2cccnc21 +COc1ccc(NC(=O)Nc2onc(C)c2C)c(Cl)c1 +COc1ccc2cc(NC(=O)c3cccc(C)c3)cnc2c1 +Brc1cccc(CNCCc2ccncc2)c1 +COc1cc(CNc2ccc3c(c2)CCC3)cc(OC)c1O +CC(Sc1ncn[nH]1)C(=O)Nc1ccc(Br)cc1 +O=C(Cn1c(-c2nnco2)cc2ccccc21)NC1CCCC1 +O=C(c1cnsc1)N1CCCC(c2[nH]ncc2-c2ccncc2)C1 +CCOC(=O)C1=C(c2ccc(OC)cc2)NC(=O)NC1c1ccco1 +Cc1cc(N2CCC(c3ncncc3C)CC2)ncn1 +COc1ccc(Cl)cc1CNc1ccc(S(C)(=O)=O)cc1 +Cc1nc(-c2ccccn2)sc1C(=O)NCC(C)C +CC(=O)NC1CN(c2cccc(C#N)n2)CC1c1ccc(C)o1 +CCCCC(NC(N)=O)C(=O)Nc1nnc(C(C)C)s1 +Cc1cc(C2Cc3ccc(Br)cc3C2)[nH]n1 +O=C(NCc1ccc(F)cc1Cl)c1ccn2nccc2c1 +Cc1cc(CNc2cnn(CC(C)C)c2)ccc1F +COc1cc(-c2c(F)cc(F)cc2F)ccc1O +N#Cc1ccccc1C(=O)NC1CCN(c2c(F)cccc2F)C1 +CN1C(=O)C(C)(C)COc2ccc(NC(=O)Cc3cccs3)cc21 +CN(C)C(=O)CNC(=O)c1c[nH]nc1-c1ccc(Cl)cc1 +O=C(c1nccs1)C1CCN(C(=O)c2n[nH]c3c2CCC3)CC1 +CCN(C(=O)c1cnc(C)cn1)c1cc(C)ccc1C +COCCNC(=O)CN(C)C(=O)c1cc(SC)ccc1C +Cc1c(CCC(=O)N2CC(C)OC(C)C2)cnn1C +CCOc1ccc(NC(=O)CCC(=O)n2nc(C)cc2C)cc1 +CCC(C)Sc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1ccccc1 +COc1ccc(OC)c(Nc2nc(C)cc(=O)[nH]2)c1 +COCc1cccc(CNC(C)C(=O)NC2CC2)c1 +CCn1cc(-c2cc(C(F)(F)F)nc(N3CCOCC3)n2)cn1 +COc1cccc(CN(C)S(C)(=O)=O)c1OC +Cc1ccc2oc(C(=O)Nc3ccc(S(N)(=O)=O)c(C)c3)cc2c1 +Cc1ccc(-c2noc(C(=O)N3CCCC3)c2N)cc1 +Cc1cc(NC(=O)c2cc[nH]n2)n(-c2cccc(Br)c2)n1 +CN(CCCOc1ccc(F)cc1)C(=O)Cn1cc(Cl)cn1 +CN(C)C(=O)c1ccccc1NC(=O)c1ccc(Br)cc1 +Cc1cc(C)c2sc(NC(=O)c3cc(C)no3)nc2c1 +CN(C)C(=O)CNc1cncc(Br)c1 +CSc1nnnn1-c1ccc(C(=O)Nc2ccc(F)cc2)cc1 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(N)nc1 +Cc1ccc(CC(C)NC(=O)COc2ccccc2C#N)s1 +Cn1nccc1C(=O)OCC(=O)Nc1ccc2ccccc2c1 +CCNC(=O)CSc1ccc(-c2cccs2)nn1 +O=C(CC(c1ccccc1)c1ccccc1)NC1CC(O)C(CO)C1 +Cc1ccc(-c2cc(Cn3c(=O)oc4cccnc43)on2)cc1 +O=C(Nn1cnc2ccccc21)c1c(F)cccc1Cl +CC(C)c1c(OCc2ccccc2)nc2n(c1=O)CCS2 +OCc1nnc2n1CCN(Cc1ccccc1N1CCCC1)C2 +CN(CCc1ccncc1)C(=O)c1nc2ccc(F)cc2[nH]1 +CCc1nn(C)c2[nH]nc(NC(=O)c3cccc(OC)c3F)c12 +COc1ccccc1NC(=O)c1csc(-c2cnccn2)n1 +Cc1cc(C(O)CCCC(=O)NC2CC2)ccc1F +CCCn1nc(-c2cc(F)ccc2F)cc(C(C)=O)c1=O +CCCn1c(CNC(=O)COC)nc2ccccc21 +CC(=O)N1CCC(C(=O)OCC=Cc2ccccc2)CC1 +CC(NS(=O)(=O)c1ccc2[nH]c(=O)[nH]c2c1)C(=O)N1CCCC1 +N#CC(C(=O)c1nn(-c2ccccc2F)c2c1CCC2)c1ccccn1 +O=C(c1cc(-c2ccc(F)cc2)c[nH]1)N1CCc2ncncc2C1 +NC(=O)c1ncccc1NC(=O)c1cc(C2CC2)nc2ccccc12 +CC(Cc1cccc(F)c1)C(=O)N1CCC(C(=O)N2CCCC2)CC1 +CC(C)(C)C(=O)OCc1cc(=O)n2ccsc2n1 +CC(=O)NC1(c2ccccc2)NC(=O)c2ccccc21 +CC(NC(=O)CCNC(=O)c1ccco1)c1cccc(Cl)c1 +Cc1nc(CC(=O)N2CCC(Oc3cccc(Cl)c3)C2)cs1 +COc1ccc(NC(=O)c2cc(NC(C)=O)ccc2O)cc1Cl +COC(C)c1noc(-c2cc(C3CC3)nc3onc(C)c23)n1 +Cc1nn(C)c2ncc(CNc3cc(C(=O)N(C)C)ccn3)cc12 +Cc1cccn2cc(CSc3nnnn3C(C)C)nc12 +Cc1cc(C)cc(NCC(=O)c2ccc3c(c2)OCCO3)c1 +N#CCSc1nnc(NC(=O)Nc2cccs2)s1 +COc1ccc(F)c(NS(=O)(=O)N2CCCC(C)C2)c1 +CCN(CC)S(=O)(=O)c1cc(Cl)c(N)c(Cl)c1 +O=C(CCn1cnc2ccccc2c1=O)N1CCCC1 +CCN(CC(O)c1ccc(F)c(F)c1)c1ccccc1 +CCCCNC(=O)CNc1ccccc1C(=O)N1CC(C)CC(C)C1 +N#Cc1ccc(S(=O)(=O)N2CCCc3ccccc32)cc1 +O=c1c2nnc3ncnn3c2ccn1CCCN1CCOCC1 +Cn1ccc2c(C(=O)Nc3cccc4ncccc34)cccc21 +CC(=O)N1CCCC(c2nccnc2-c2cccc(C(N)=O)c2)C1 +COc1ccccc1Nc1ncnc(Nc2nc(C)c(C)s2)c1N +CCN(CC)S(=O)(=O)c1ccc(NC(=O)C2CCC(=O)N2)cc1 +CCC(NCc1cccc(F)c1)c1nccs1 +CN(C(=O)C1CC(=O)N(C2CCCCC2)C1)c1ccccc1 +O=S(=O)(Nc1cnn(C2CCOCC2)c1)c1ccc(F)cc1 +COc1ccc(CC2CCN(C(=O)Nc3cn[nH]c3)CC2)cc1 +FC(F)(F)c1cccc(-n2cnc3cccnc32)c1 +COCC(=O)Nc1ccc(NC(=O)NCc2ccc(F)c(C)c2)cc1 +CN(C(=O)c1ccncc1F)c1cccc2ncccc12 +Cc1ccc(C(=O)COC(=O)CNC(=O)c2ccco2)cc1C +Cc1ccc(SCCNC(=O)c2ccc3c(c2)OCC(=O)N3)cc1 +O=C(NCc1ccccc1OC(F)F)c1ccc(F)cc1 +Cc1ccc(NC(C)C(=O)Nc2nnc(C)s2)cc1 +Cc1nc2cc(-n3ccnc3-c3nccn3C)ccc2[nH]1 +CCOCCCNC(=O)c1cnc(N(C)C)nc1C +CCN(CC(=O)NC(C)(C)C)C(=O)c1cc2ccccc2o1 +COc1ccc(NC(=O)c2ccccc2NCc2cccnc2)cc1 +C#CCOc1cccc(NC(=O)N2CCCC2c2c(C)n[nH]c2C)c1 +O=C1C(=O)N(Cc2cccc(F)c2)c2cc(Br)ccc21 +CCNC(=O)NCc1nc(Cc2ccccc2)no1 +Cc1cc(NC(=O)CCc2ccccc2)c2cc(F)ccc2n1 +CC(Sc1nccn1C)c1nnc(-c2ccccc2)o1 +CNC(=O)CCCS(=O)(=O)c1cccc(C)c1 +Cc1n[nH]c(C)c1NC(=O)CSc1nnnn1C(C)C +CC(NC(=O)c1ccccc1-c1ncc[nH]1)c1nc2ccccc2[nH]1 +COc1ccccc1CCC(=O)NCc1ccc(F)cc1 +O=C(Nc1ccc2c(c1)OCO2)C(Cc1ccccc1)n1cnnn1 +CCC(C)Oc1ccc(NC(=O)CN(C)C(=O)c2ccccc2)cc1 +CC(=O)Nc1ccc(-c2nc3ccccc3o2)cc1 +CN(CC1CC1)C(=O)CNC(=O)c1ccc(F)c(F)c1 +CCC(CC)CN(CC)C(=O)C1(C#N)CCCC1 +Cc1ccc(-c2cc3c(=O)n(CC(=O)N4CCCC4)ncn3n2)cc1 +CC(=O)c1cc2ncc(C(=O)N3CCOCC3)cc2[nH]1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1cc(Cl)ccc1F +CCC1CCCN(C(=O)c2cc(OC)ccc2N)C1 +Cc1cnccc1-c1cnc(N(C)C)nc1-c1ccco1 +CC(C)c1ccc(C=CCC(=O)N2CC(CO)OCC2C)cc1 +CC(=O)N1CCCC1C(=O)NCC1CCC(C)(C)CC1 +Cc1cc2n(n1)CCC(=O)N2Cc1ccc(C(=O)NC2CC2)cc1 +NC(=O)N1CCCC(C(=O)N(Cc2ccco2)Cc2ccco2)C1 +COc1ccc(C(=O)NCCCC(=O)Nc2cccc(C)c2)cc1 +CCc1sc2nc(C)c(N)n2c1-c1ccc(OC)cc1 +Oc1ccc(C(O)C2NCCc3cc(Cl)ccc32)cc1 +N#Cc1cccnc1NCCNC(=O)CCc1ccccc1F +CC(c1ccncn1)N(C)Cc1cc(=O)c2cc(F)ccc2[nH]1 +COc1ccc(CN(C)C(=O)COc2nnc3ccccn23)cc1 +CC(C)Cc1nc(C(=O)NCCC(=O)N(C)C)cs1 +CN(C)S(=O)(=O)NCc1ccc2c(c1)OCO2 +Cc1ccc(-c2nc(C(=O)N3CCCC(C(N)=O)C3)cs2)c(C)c1 +COc1ccc(C)cc1S(=O)(=O)Nc1ccccn1 +N#Cc1ccc(OCc2ccc(F)cc2C#N)cc1 +Cc1nnc(SCC(O)c2ccccc2)n1C1CC1 +CCc1ccccc1NS(=O)(=O)c1ccccc1N +COc1ccc(C(=O)N2CC(c3nc(-c4ccccn4)no3)C2)cc1 +O=C(CNC(=O)c1ccsc1)Nc1ccccn1 +COC(=O)c1cc(NCc2ccncn2)ccc1F +Cn1c(=O)[nH]c(=O)c2cc(S(=O)(=O)NC3CCCCC3)cnc21 +Cc1c(CN2CCOC(c3nccs3)C2)cc(C#N)n1C +COC(=O)Nc1cccc(NC(=O)c2ccc(N(C)C)cc2)c1 +CS(=O)(=O)c1ccc(CC(=O)NCCc2ccccc2)cc1 +CC(C)N(C(=O)Cn1cnc2cc(F)c(F)cc21)C(C)C +COCC(=O)Nc1c(C(=O)NC(C)(C)C)oc2ccccc12 +CCC(C)NC(=O)NC1CCOc2c(Cl)cccc21 +COc1ccccc1C(C)NC(=O)c1cccc(NC(C)=O)c1 +Cc1n[nH]c(C)c1CNC(=O)Cc1c[nH]c2ccccc12 +COc1ccc(NC(=O)c2cn(-c3ccc(Cl)cc3)nn2)cn1 +CCn1c(SCC(=O)N2CCCCC2C)nc2ccccc21 +COc1ccc(F)cc1C(C)NC(=O)Nc1nncs1 +CC1CN(CCNc2cccc(Cl)c2)C(C)CO1 +CCn1nc(C(=O)N2CCOC3CCCC32)c2ccccc2c1=O +Cc1ccc(OC(=O)c2cnn(-c3ccncc3)c2C)cc1 +COc1cc(N2CCC3(CC2)NC(=O)CC3c2ccncc2)ncn1 +CCn1ccc(C(=O)Nc2ccc(C(=O)OC(C)C)cc2)n1 +CC(C)NC(=O)c1cc2c(cn1)[nH]c1ncccc12 +Cc1ccccc1C1CN(Cc2cccs2)CCO1 +COc1cc(C(=O)Nc2ccccn2)cc(OC)c1OC +Cc1ccccc1Cn1cc(NC(=O)Cc2ccccc2)cn1 +Cc1nc(-c2ccccc2)ccc1C(=O)NC(C)CO +CCN(CCO)C(=O)Nc1cccc(C(C)=O)c1 +CN(Cc1nccn1C(F)F)C(=O)NCc1ccc2c(c1)CCC2 +CCC1(CC)CN(CCC#N)c2ccc(F)cc2N1 +CNc1ccc(Cl)cc1C(=O)Nc1cccnc1 +N#Cc1ccc(NCCC(=O)Nc2ccccn2)nc1 +C=CCN(CC=C)S(=O)(=O)c1ccc(Cl)c(N)c1 +CC(C)c1noc(-c2ccccc2OCC(=O)NCc2ccco2)n1 +O=C(NCCc1nc2c(s1)CCCC2)NCC(F)(F)F +Nc1cnn(CCCOc2ccccc2Cl)c1 +CC(=O)Oc1ccc2c(C)c(CC(C)C)c(=O)oc2c1 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccc(Cl)cc1 +O=C(NCC1CN2CCCC2CO1)c1ccc(Br)cc1 +CC(=O)NCC(=O)NCC(=O)N(Cc1ccccc1)C1CC1 +CCCOc1ccc(CNC(=O)Nc2ccccc2F)cc1OC +CC1Cc2ccccc2N1CC(=O)N1CCCC(C(N)=O)C1 +Cc1cc(Oc2ccc(C#N)cc2)ccc1NC(=O)N(C)CCO +COC(=O)C(NC(=O)Nc1ccc(OC)cc1)C(C)C +Cn1c(=O)c2ccc(C(=O)NCCN3CCOCC3)nc2n(C)c1=O +Cc1ccc(O)c(C(=O)N2CCN(Cc3ccccn3)CC2)c1 +COc1ccc(-c2cccc(C(=O)NCCCO)c2)cc1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NCCc1cccs1 +COc1cc(F)c(C(C)NC(=O)CCc2cccnc2)cc1OC +CN(C)S(=O)(=O)c1cccc(CNc2ccc(C(N)=O)cc2)c1 +C=CCN(CCO)S(=O)(=O)c1ccc(F)cc1 +c1cnc(Oc2ccc(CN3CCOC4(CCCC4)C3)cc2)cn1 +CC=CC=CC1NCCc2c1cc(F)c(F)c2F +CN(CCc1ccncc1)Cc1ccccc1C#N +CC(=O)NC1CCCN(C(=O)NC2CCC(c3ccccc3)CC2)C1 +CC(=O)c1cccc(NC(=O)c2cccc(S(=O)(=O)N(C)C)c2)c1 +O=C1NC(c2ccc(-n3ccnc3)cc2)Nc2cc(Cl)ccc21 +COCc1cccc(CNC(=O)NCC(=O)Nc2cccc(F)c2)c1 +COCC(=O)NC(CC(C)C)c1nc2ccccc2[nH]1 +CCC(OC)C(=O)Nc1[nH]nc(C(F)(F)F)c1C +Cc1occc1C(=O)N1CC2(CCN(c3ncccn3)C2)C1 +O=C(CCCc1nc2ccccc2[nH]1)NCC(F)(F)F +Cc1cccc(-n2nnc(-c3nc(-c4ccncc4)no3)c2N)c1C +NC(=O)C1CCCN(C(=O)Cc2ccc(Cl)cc2Cl)C1 +CC(C)NC(=O)Cn1c(C(C)NC(=O)C(C)C)nc2ccccc21 +CCn1ccc(C(=O)Nc2nnc(-c3ccc(OC)cc3)s2)n1 +CCOCCCNC(=O)C1CCN(c2ccccc2)CC1 +COc1ccccc1NC(=O)c1c(-n2cnnn2)sc(C)c1C +Cc1noc(C)c1COc1cccc(C(=O)N2CCCC(C)CC2)c1 +CC(C)C(Sc1ncnc2c1cnn2C)C(=O)NC1CCCC1 +N#Cc1cccc(NC2C(=O)Nc3cccc(Br)c32)c1 +COC1COC2(CCN(C(=O)c3ccoc3)C2)C1 +O=C(OCC(=O)N1CCCCCC1)c1n[nH]c(=O)c2ccccc12 +Cc1cc(OC(C)(C)C(=O)NCCCn2ccnc2)ccc1Cl +CN(C)c1nc2cc(NC(=O)CCN3CCCC3=O)ccc2o1 +O=C(COc1cccnc1)NCc1cnn2ccccc12 +CCNc1nc2c(s1)C(c1ccc3c(c1)OCO3)CC(=O)N2 +CCc1ccc(S(=O)(=O)N(C)CCC#N)cc1 +CCC(NC(=O)c1cc(S(N)(=O)=O)oc1C)c1ccncc1 +CC(=O)c1ccc(S(=O)(=O)Nc2cc(C)ccc2F)cc1 +CC(=O)c1ccc(S(=O)(=O)N(C)Cc2cccnc2)cc1 +COc1cc(-c2coc3ccc(O)cc23)cc(OC)c1OC +Cc1ccc(OCC(CC#N)N2CCOCC2)cc1C +Cc1nc(C(C)N(C)C(=O)c2ccncc2)c(C)s1 +O=C1CN(C(=O)C2CCCN2C(=O)c2ccco2)CCN1 +Cc1nc(C)c(-c2c(F)cccc2Cl)c(N)n1 +COc1ccc(-c2nc(Cn3c(=O)oc4cccnc43)no2)cc1 +CN(C)c1ccc(C(=O)NCCc2ccc(C(F)(F)F)cc2)cn1 +CN(CCOc1ccccc1F)Cc1ccc(C#N)cc1F +CN(CCc1ccccn1)C(=O)CNC(=O)N1CCCC(CO)C1 +CCn1ncc(S(=O)(=O)N2CCCC(c3cncc(C)n3)C2)c1C +CCCOc1ccc(C(=O)N2CCCCCC2)cc1OCC +c1ccc(CN2CCc3nnc(CNc4ncccn4)n3CC2)nc1 +CN(CC(=O)NCCN1CCCc2ccccc21)C(=O)c1ccco1 +CCCn1cnnc1COC(=O)c1cnc(C2CCCO2)s1 +COc1c2ccc(C(=O)NC3CCCCCC3)cc2nn1C +CC(C)(C)C(=O)NCCCNC(=O)c1ccccn1 +CCc1cc(C(O)COC)cc2c1NC(=O)C2CC +Cc1occc1C(=O)NCC(=O)NC(C)Cc1cccc(Cl)c1 +O=C(NCC(O)c1ccsc1)c1ccc(Br)cc1 +Cc1cc(C)c2nc(-n3ncc(C#N)c3N)sc2c1 +Cc1ccc(N2Cc3ccc(N)cc3C2)cc1Cl +Cc1ccc(C(O)CCNc2ccc(F)cc2)cc1 +CCCCc1ccc(C(O)CN2CCN(C(C)=O)CC2)cc1 +O=C(Cn1c(C(F)(F)F)nc2ccccc21)NCC(F)(F)F +CC(Sc1nc(-c2cccnc2)n[nH]1)C(=O)NC1CCCC1 +CCNC(=O)c1ccc(NC(=O)C(C)Cc2ccccc2F)cc1 +CC(NC(=O)CN1CCc2ccccc21)c1cccs1 +O=C1NC2=C(CCc3ccccc32)C(c2ccccc2)N1 +CC(OC(=O)C1CC1C)C(=O)N(C)Cc1nc2ccccc2s1 +Cc1cccc(OCCN(C)C(=O)c2nc3nccc(C)n3n2)c1 +COC(=O)CN(C(=O)C1CC2C=CC1C2)C(C)C +CC(=O)Nc1ccc(NC(=O)Nc2ccccc2CC(N)=O)cc1 +CC(C#N)N(C)C(=O)c1ccc(S(=O)(=O)N(C)C)cc1 +CC(C)C(C)NC(=O)Nc1ccc(NC(=O)C2CCCO2)cc1 +CC1(C)Oc2cc(CO)ccc2N(CC(N)=O)C1=O +Cn1ncc2c(=O)n(CCC(=O)Oc3ccc(Cl)cc3)cnc21 +CC(Oc1ccc(F)c(F)c1)C(=O)N1CCCC1c1ccccn1 +CCCn1nc(C(=O)N(CC)C(C)c2ccc(F)cc2)ccc1=O +Cc1cccc(OC(C)(C)C(=O)N2CC(C)OC(C)C2)c1 +CC(c1nc(-c2cccs2)no1)S(=O)(=O)c1ccc(O)cc1 +Cc1cc(Br)cc2c1CCNC2c1cc[nH]n1 +CC(C)OC(=O)CC(Nc1ccc2nnnn2n1)c1ccccc1 +O=C(CC1CCCC1)Nc1ccc(-n2cncn2)c(F)c1 +COc1ccc(-c2c(C(C)C)nn3c(N)c(C#N)nnc23)cc1OC +COc1ccc(C2(CNC(=O)c3c(C)noc3C)CCOCC2)cc1 +Cc1cc(C(=O)N2CCCC2)ccc1NC(=O)C1CC2C=CC1C2 +Cc1ccc(C(=O)N2CCCN(Cc3nccn3C)CC2)cn1 +Cc1ccc(C(=O)NCC(=O)Nc2cccc(Cl)c2C)o1 +COCC(C)NC(=O)c1cc(-c2ccc(Cl)cc2Cl)on1 +CC(C)CC(CNC(=O)Cc1noc2ccccc12)N1CCOCC1 +Cc1cccc(C)c1NC(=O)C(C)Sc1nnc2ncccn12 +CCCS(=O)(=O)NCCNC(=O)c1ccc(Cl)cc1 +CC12CC3CC(C)(C1)CC(N1CC(C(N)=O)CC1=O)(C3)C2 +Cc1ncccc1NC(C)c1cccc(S(=O)(=O)N(C)C)c1 +Cc1cc(C)n(CC(=O)Nc2nc(CC(N)=O)cs2)n1 +COCCc1ccc(OC(=O)Cc2c[nH]c3ccccc23)cc1 +C=CCN(CC=C)C(=O)C1CCN(c2ccc3nncn3n2)CC1 +O=C(OCc1ccc(-n2cccn2)cc1)c1ccnc(-n2ccnc2)c1 +COCc1ccc(C2CCCN2C(=O)NCCc2ccnn2C)o1 +O=C(CCCc1cn[nH]c1)N1CCCC(C(=O)N2CCOCC2)C1 +CC(=O)Nc1ccc(F)c(NC(=O)NC2CCc3c(O)cccc32)c1 +COc1ccc2nc(NC(=O)N3CCCC(O)C3)sc2c1 +Cc1nnc(SCCCNC(=O)c2cc(C(C)C)n[nH]2)s1 +COc1cc(NC(=O)CS(=O)(=O)c2ccc(C)cc2)cc(OC)c1 +COC(=O)C1CCN(c2ccc(-c3ccccc3OC)nn2)CC1 +COCCN(Cc1ccccn1)S(=O)(=O)c1cc(C)oc1C +COc1cc(COc2ccc(C#N)cc2F)cc(OC)c1OC +O=C(Cn1cnc2ccccc21)Nc1nc2c(s1)C(=O)NCCC2 +COCCNC(=O)CN(C)c1ccc(C)cc1N +Cc1cc(-n2nc(C)cc2C)n2ncc(-c3ccccc3)c2n1 +CCCNC(=O)C1CCCN(C(=O)Nc2cccc(C(C)=O)c2)C1 +CC(C)OCCC(=O)NCC(O)c1ccc(Cl)cc1 +COCc1cccc(NC(=O)N2CCN(c3ccccc3F)CC2)c1 +Cc1ccc(NC(=O)c2ccc[nH]c2=O)cc1S(=O)(=O)N(C)C +COc1ccc(CNc2cn[nH]c(=O)c2Cl)cc1OC +Cc1nc(C(NC(=O)Cc2ccn[nH]2)c2ccc(Cl)cc2)no1 +CCC(C)NC(=O)c1ccc(Cl)c(S(=O)(=O)NC(C)(C)C)c1 +CCCCCN1C(=O)C2(OCCO2)c2cc(C)ccc21 +CCCc1noc(CS(=O)(=O)c2nccn2C)n1 +O=C(Nc1ccc2[nH]ncc2c1)c1cnn2c1OCCC2 +CCC(=O)Nc1nc2c(Br)cccc2s1 +COc1cc(C)c(C(=O)NCCOc2cccc(Cl)c2)cc1OC +CN1CCN(C(=O)c2ccc(-n3ccnn3)cc2)C(c2ccccc2)C1 +O=C(NCc1cccnc1)C1CCN(C(=O)c2cccc(F)c2)CC1 +CCN(c1cccnc1)S(=O)(=O)c1cccc(C#N)c1 +COC(=O)C(C)NC(=O)Cc1ccc(Cl)cc1 +Cc1ccc(-c2ccc(C(=O)N(C)CCN3CCCC3=O)s2)o1 +Cc1ccccc1OCCN(C)C(=O)CCn1ccccc1=O +Cn1cc(C(=O)NCC(=O)NCCc2ccccc2)c(C(C)(C)C)n1 +CCCNC(=O)CN1CCN(S(=O)(=O)c2ccc(C)cc2)CC1 +COc1ccc(COCC(=O)Nc2ccc(N)cc2C)cc1 +CCCc1nnc(N2CCC(CCC(=O)NC3CC3)CC2)o1 +CC(=O)NC1Cc2ccccc2C1Nc1cc(C2CC2)ncn1 +Cc1cnc(CN(CC(C)C)c2cccc(O)c2)cn1 +Cc1cccc(C(=O)Nc2ccc(CN3CCCC3=O)cc2)c1 +O=C(NCc1ccc(S(=O)(=O)N2CCCC2)cc1)N1CCCC1 +CSc1ccc(CN(C)C(=O)Cn2ccccc2=O)cc1 +CC(=O)Nc1ccc(NC(=O)C(C)Sc2ccccn2)cc1 +COc1cc(NC(=O)c2ccc3[nH]nnc3c2)cc(OC)c1 +CN(CCc1ccc(F)cc1)C(=O)c1n[nH]c2c1CCC2 +Cc1cc(C)cc(NCC(O)Cn2nnnc2-c2ccccc2)c1 +CCn1c(C)nnc1SCCC(O)c1ccccc1 +COc1ccc(F)cc1NC(=O)COC1CCCCC1C +COCC(=O)NCC1CCN(C(=O)c2cc(C)on2)CC1 +COc1cc2[nH]c(=O)n(CCNc3ccccc3)c(=O)c2cc1OC +CCC(=O)NCC1CCN(C(=O)Oc2ccccc2)CC1 +O=C(Nc1ccc(CC(=O)N2CCC(O)CC2)cc1)c1ccccc1 +C=CCNc1oc(COc2ccc(F)cc2)nc1C#N +Nc1cc(NC(=O)CSc2nncs2)ccc1F +CC(=O)Nc1cccc(C(=O)N(Cc2ccccc2)Cc2ccco2)c1 +N#CC1COCCN1C(=O)CCc1cccc(Cl)c1Cl +COc1ccc(N(Cc2ccc(O)cc2)C(=O)c2ccccn2)cc1 +CC1COCC(C)N1Cc1cnn(-c2ccccc2)c1 +CCC1CCCC(NC(=O)N(C)CCCNC(C)=O)C1 +CN(Cc1nc(-c2ccccc2)no1)C(=O)Cc1ccccc1 +CCNc1ccc(S(=O)(=O)N2CCOCC2)cn1 +Cc1nc2ncc(C(=O)N(C)Cc3cn(C)nc3C(C)C)cc2[nH]1 +CS(=O)(=O)NCCNC(=O)CNC(=O)c1ccsc1 +O=C(CCC1CCCC1)NCCC(O)c1ccco1 +CN(Cc1ccccc1)C(=O)c1cn2c3c(cccc3c1=O)CC2 +Cc1ccc(C(=O)N2CCC(c3nc4ccccc4o3)CC2)n1C +Brc1cnc2oc(N3CCOCC3)nc2c1 +CCOC(=O)c1ccc(NC(=O)Cc2ccccc2N)cc1 +CCc1nnc(NC(=O)N(CC)C(C)C(C)C)s1 +CCOc1ccc(S(=O)(=O)n2ccnc2)c(OCC)c1 +Cc1n[nH]c(SCC(=O)Nc2cc(S(N)(=O)=O)ccc2C)n1 +COc1ccc(N)cc1-c1nnc(C2CCCC2)o1 +Clc1cccc(Cl)c1COc1ccc(-n2cnnn2)cc1 +Cc1nc(C)c(C(=O)NCC(C)(O)c2ccc(F)cc2)o1 +O=C(COCC(F)(F)F)NC1CCN(c2ccccc2)CC1 +Cc1cc(C)n(CC2CCN(C(=O)c3ccc4nccnc4c3)CC2)n1 +Cn1ccc(C(=O)Nc2c(C(N)=O)oc3ccccc23)n1 +Cc1cc(C(=O)N2CCOCC2)ccc1NC(=O)CC(F)(F)F +Cc1cc(=O)c(OCC(=O)N2CCN(C(=O)c3ccco3)CC2)c[nH]1 +COC(=O)c1scc2c1Nc1ccccc1S2(=O)=O +CC(C)(C)C(=O)N1CCc2cc(NC(=O)C3CC3)ccc21 +O=C(COc1ccc(F)cc1)N1CCN(C(=O)c2ccco2)CC1 +CC(C)(C)Oc1cc(CNC(=O)c2ccc3c(c2)CCO3)ccn1 +COC(=O)c1ccc(CSc2nnc3ccccn23)cc1 +Cc1ccc(S(=O)(=O)C(C)C(=O)N2CCCCC2)cc1C +O=c1c(Br)coc2ccc(Cl)cc12 +CC(C)c1ccc(C(C#N)N2CCC(O)CC2)cc1 +O=C(c1ccnnc1)N1CCc2onc(CNc3ncccn3)c2C1 +COCCOCC(=O)Nc1nc2c(OC)cc(F)cc2s1 +O=S(=O)(NCc1nc2cccnc2n1C1CC1)c1ccc(F)cc1 +Cc1cc(C)c(NC(=O)CC(C)C#N)c(Cl)c1 +N#Cc1ccnc(SCC(=O)c2ccc(F)c(F)c2)c1 +Cc1nn(C)c(C)c1C1CC(O)=Nc2c1c(=O)[nH]n2C1CCCC1 +CN(CC(F)(F)F)C(=O)c1cc(-c2cccs2)on1 +CC(C)(C)CC(=O)Nc1ccc2c(c1)OCCCO2 +Cc1c(C(=O)N2CCOCC2)nc2c(Cl)cccn12 +O=S(=O)(NCc1ccnc(Oc2ccccc2)c1)N1CCCCC1 +COc1cc(CN(C)C(=O)c2cn[nH]c2)ccc1O +O=C(CCCc1ccccc1)NCCN1CCOCC1 +COc1ccccc1OCCCC(=O)n1ccnc1 +CCOC(=O)N1CCCC(C(=O)Oc2ccc(C#N)cc2Cl)C1 +O=C(NCc1cnc2c(c1)CCC2)c1cnnn1-c1ccccc1 +CCCc1cc(C(=O)NC2c3ccccc3CC2NC(C)=O)no1 +COc1ccc(CNc2nc3c(C)nn(C)c3c(=O)n2C)cc1OC +Cc1ccc(Oc2ccc(NC(=O)c3nccnc3N)cc2)cc1 +CN(CCc1ccccn1)C(=O)c1cccc(Oc2ccccc2)c1 +CN(CC1COc2ccccc2O1)C(=O)CCc1cccs1 +COCCNC(=O)CCS(=O)(=O)c1ccc(Cl)cc1 +OCc1nc2ccccc2n1CCCOc1ccc(F)cc1 +C=C(C)COCCNC(=O)c1cnc2ccc(C)cn12 +COc1ccc(NC(=O)Cc2cccc(C)c2)c(OC)c1 +CC(Cc1ccc(Cl)cc1)N(C)C(=O)NCc1ncn(C)n1 +Cc1cnn(CCC(=O)NC(C)c2cc3ccccc3o2)c1 +CC1CC1CNC(=O)NCCc1cccc(F)c1 +Cc1ccc(C(C#N)CC(=O)NCc2ccncc2)cc1 +COCc1nn2c(=O)cc(COC(=O)c3ccc(C)cc3)nc2s1 +COCC(=O)Nc1ccccc1Oc1cccc(C)c1 +COCC(=O)N1CCC2(CC1)CC(OCc1ccccn1)CO2 +CCOC(=O)C1=C(C)OC(N)=C(C(=O)OCC)C1c1cccnc1 +CCOc1ncccc1NC(=O)N1CC=C(c2ccc(O)cc2)CC1 +CC(C)NC(=O)Nc1ccc(C(=O)N2CCOCC2(C)C)cc1 +CCC1CCCN(C(=O)Nc2nc(-c3cccnc3)cs2)C1 +CCOC(=O)c1cc(-c2ccc(OC)c(Br)c2)n[nH]1 +CCn1ccnc1CSc1nc(-c2ccc(C)cc2)n[nH]1 +O=C(Cc1cc(-c2ccccc2)on1)NCc1ccco1 +Cc1ccc2oc(C(=O)N(C)c3ccccc3)cc2n1 +Cc1ccc(C(=O)OCCn2nc3ccccn3c2=O)cc1 +C=CCCOC(=O)c1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +O=C(CNC(=O)C1CC1)Nc1cc(Cl)ccc1Cl +COC(=O)c1sccc1S(=O)(=O)Nc1cc(Cl)ccc1C +COc1ccc(C)cc1S(=O)(=O)NCc1ccco1 +CCCN(Cc1cccc(N)c1)C(=O)COCC +Cc1cnc(C(=O)N2CCCC2c2nc(-c3ccccc3)n[nH]2)cn1 +O=S(=O)(NCc1nnc2ccccn12)c1ccccc1 +COC(=O)C1CC(=O)N(c2cc(C)ccc2OC)C1 +O=C(Nc1ccc(F)c(F)c1)c1cc2ccccc2oc1=O +CCOc1cc(NCC2CCCO2)nc(CC)n1 +CC(=O)Nc1cccc(-c2nnc(-c3ccco3)o2)c1 +CC(=O)c1ccc(C#CCNS(=O)(=O)Cc2ccc(F)cc2)cc1 +O=S(=O)(NCc1ccccc1Cn1cccn1)c1ccc(F)cc1 +CNC(=O)CCc1nc2c([nH]1)c(=O)[nH]c(=O)n2C +Cc1nnc2n1CCCC2NC(=O)Nc1ccccc1OC(F)F +Cc1nn(C)c(C)c1C(=O)N(CCCO)C(C)C +COC(=O)Cn1ccc(NC(C)c2cc(F)ccc2F)n1 +CN(CC(N)=O)C(=O)Cc1csc(-c2ncccn2)n1 +CCCn1c(C)nnc1SCC(=O)Nc1ccccc1CC +Cc1ccsc1CNC(=O)NCc1cn2ccsc2n1 +Cc1n[nH]c(C)c1CCC(=O)Nc1cccc(N2CCCCC2)c1 +CC(C)(C)n1cc(NC(=O)c2cc(Cl)c[nH]2)cn1 +CC(=O)NCC(=O)N1CC2CCN(c3cncnc3)C(=O)C2C1 +COc1cccc(C(=O)N(C)CC(=O)N(C)C)c1 +Nn1c(COc2ccc(F)cc2)nnc1SCc1ccccn1 +CCN(CC(C)C#N)C(=O)CNc1ccn(-c2ncccc2Cl)n1 +COc1ccccc1NC(=O)c1cn2c(C)cccc2n1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(F)c(COC)c2)cc1 +CCc1ncc(NC(=O)N2CC=C(c3ccccc3Cl)CC2)cn1 +COc1ccc(C(=O)CCC(=O)N2CCc3ccccc32)cc1 +C=CCNC(=O)Nc1ccc(NC(=O)Nc2cccc(C#N)c2)cc1 +COCc1ccc(CN2CCNC(=O)C2c2ccccc2)o1 +CC(C)Cc1ncc(CNC(=O)NC2(CCO)CCC2)s1 +COC(=O)CN(C(=O)Cc1c(F)cccc1F)c1cccc(F)c1 +COc1ccc(CCC(=O)Nc2cccc3nonc23)cc1 +CNC(=O)c1cn(-c2ccc(F)cc2)nc1-c1ccc(C)cc1 +CC(C)NS(=O)(=O)c1cccc(C(=O)NCc2cccs2)c1 +CCC(C(=O)Nc1cc(C)nn1C)c1ccccc1 +Cc1ccc2c(=O)c(C(=O)N3CCC(C(N)=O)CC3)c[nH]c2n1 +COc1ccc(CNC(=O)c2cc3sc(C)cc3n2C)cc1 +Cn1cc(Br)cc1C(=O)Nc1ccc2nc[nH]c(=O)c2c1 +CC(=O)c1ccc(CNC(=O)c2ccoc2)nc1C +CCn1nc(C)c(C(=O)NC(C)c2ccc(C(F)(F)F)cc2)c1C +CCOCC(=O)Nc1ccc(C)cc1Br +CCCN(C)C(=O)Nc1cc(-c2ccccc2)on1 +Cc1cccc2c1C(C(=O)NC1CCCCCC1)CNC2 +Cc1cc(C(=O)N(C)Cc2cccs2)c2cnn(C(C)C)c2n1 +O=C(CCn1ncc2cc(Cl)ccc21)NCc1cccc(F)c1 +Cc1ccc(S(=O)(=O)c2noc(C(N)=O)c2N)cc1C +NC(=O)CCn1c(=O)oc2cc(S(=O)(=O)N3CCCC3)ccc21 +Cc1ccc(C(=O)N(C)C)cc1NC(=O)C1CCCO1 +CCN(CC)C(=O)N1CCN(Cc2noc3c2CCCC3)CC1 +O=C(OC1CCCC1)C1CCCN1C(=O)C1CC1 +CC1CCN(C(=O)C(C)N2CCN(c3ccccc3F)CC2)CC1 +COC(=O)c1sccc1NC(=O)CSc1ccccc1Cl +COc1ccc(CNC(=O)c2cc(C)sc2C)cc1 +COc1ccc(CCNC(=O)c2c[nH]c3cccc(F)c23)cc1 +CCOC(=O)C(C)NS(=O)(=O)c1cc(C)ccc1F +Nc1cccc(-c2csc(Cc3ccc4c(c3)OCCO4)n2)c1 +CCc1onc(C)c1NC(=O)NCCn1cccc1 +CCN(CC)c1ccc(C(=O)Nc2cccn(C)c2=O)cn1 +O=c1cc(CSc2nnnn2Cc2ccco2)nc2sccn12 +COCCC(=O)Nc1ccccc1SC(C)C +C=CCn1c(C)nnc1SCC(=O)Nc1ccccc1SC +CCC1COCCN1C(=O)c1cc(C)ccc1NC +CCOc1ccc(F)c(C(=O)NCC(C)c2c(C)noc2C)c1F +NC(C(=O)N1CCc2ccc(S(N)(=O)=O)cc21)c1ccccc1 +CC(NC(=O)c1ccc(Cl)cc1)C(=O)N1CCN(C)CC1 +CCCSc1nnc(COc2ccc(C)cc2)o1 +CN1c2ccccc2C(=O)NC1c1nc(-c2ccccc2)cs1 +Cn1c(=O)c(=O)n(C)c2cc(NC(=O)CN3CCOCC3)ccc21 +Cc1ccc2c(=O)c(C(=O)Nc3cccc(F)c3)c[nH]c2n1 +CCN1CCN(C(=O)CCCOc2ccc(Cl)cc2Cl)CC1 +Cc1c(F)cccc1NC(=O)CCCCCC1NC(=O)NC1C +CCN(C(=O)C1CNc2ccccc2O1)C1CCCCC1 +COc1c(F)cc(NC(=O)c2ccccc2-n2ccnn2)cc1F +CC(=O)Nc1cccc(NC(=O)C(C)Oc2ccc(C#N)cc2)c1 +CC(NC(=O)c1ccccc1)C(=O)Nc1ccc(CC#N)cc1 +Cc1nn(CC(=O)N2CCCC(C)C2)c(=O)c2ccccc12 +CCCCc1nnc(NC(=O)c2ccc3c(c2)NC(=O)CS3)s1 +O=C(Nc1ccc(S(=O)(=O)NC2CC2)cc1)c1ccccc1 +Cc1cc(F)ccc1CCNC(=O)c1cncc(Br)c1 +Cc1ccc(NC(=O)NCc2ccnn2C)c(OCC(F)(F)F)c1 +COCCOCCNC(=O)c1nccc2ccccc12 +O=C(Cn1ccccc1=O)Nc1ccc(-n2cnc3ccccc32)cc1 +COc1ccc(CN(C)C(=O)Nc2ccc(F)cc2)c(OC)c1OC +COc1ccc(Oc2ccc(C(=O)NCc3cc(C)on3)cc2)cc1 +COc1ccc(C(C)(C)C(=O)N2CCOC(c3noc(C)n3)C2)cc1 +COCc1cc(C(=O)NC2(C(=O)OC)CCCCC2)ccc1F +O=C(NCc1ccccc1F)c1cn(-c2ccccc2)c2ncccc12 +COCCc1nnc2sc(-c3ccc(Br)cc3)nn12 +Cc1nc(NC(=O)c2cn3cccnc3n2)sc1SCC#N +CCOc1cc(CO)cc2c1OC(CC)C(=O)N2CC(O)CO +O=C(c1ccnnc1)N1CCC2(CCCN(c3ncccn3)C2)C1 +CC(C)(C)c1ccc2c(c1)S(=O)(=O)N=C(NCCCO)N2 +Cc1nn(C)c(=O)c(C(=O)Nc2nc3ccccc3s2)c1C +COCCCNC(=O)CN(C)c1nc(C)nc2[nH]ccc12 +CCN(CCC(=O)OC)S(=O)(=O)c1ccc(F)cc1F +CNC(=O)CN1C(=O)c2cc(OC)c(OC)cc2S1(=O)=O +CN(Cc1cccnc1)S(=O)(=O)C1CN(C(=O)C2CCCC2)C1 +Cc1ccoc1C(=O)Nc1cnc2c(cnn2C(C)C)c1 +COc1ccc(C2C(CO)CCC(=O)N2Cc2ccccc2)cc1 +O=C(NCCc1nnc2n1CCCCC2)c1ccccc1 +Cc1noc(COC(=O)c2ccc(COc3ccccc3)cc2)n1 +Cc1nn(C)c(C)c1CCC(=O)NCc1cscn1 +CC(Cn1ccnc1)NC(=O)c1ccc(Cl)cc1Cl +CC1CCCC(CC(=O)N2CCC(C(N)=O)c3ccccc32)C1 +CCOc1ccc(-c2nc(N)nc(C)c2C(=O)N(C)C)cc1 +CC(C)CC(C(=O)OCC(N)=O)N1CCCCC1=O +COc1ccc(OCc2ncc(CC#N)s2)cc1 +CCOC(=O)c1sc(NC(=O)COC(C)C)nc1C +CCn1cnnc1CNS(=O)(=O)c1cc(C)ccc1C +CCCNC(=O)C(C)Nc1nc2ccc(N)cc2s1 +CN(C)C(=O)c1cc2ccc(Br)cc2[nH]1 +CCOC(=O)c1cnc2c(c(C)nn2CC)c1Oc1ccc(F)cc1 +Cn1[nH]c(-c2ccncc2)c(C(=O)c2cn(-c3ccccc3)nn2)c1=O +CC1CC1C(=O)Nc1ccc(NC(=O)NC2CC2)cc1 +CCOC(=O)CCCC(=O)Nc1cccc(Cl)c1 +COc1cccc(Cc2nnc(SCCN3CCOC3=O)o2)c1 +COCC1CC2OCCN(C(=O)Cc3ccccc3)C2C1 +Cc1nn(CC(=O)N(CCO)C(C)C)c(C)c1N +O=C1C2CN(S(=O)(=O)C3CC3)CC2CN1Cc1ccncc1 +COCc1ccc(C(=O)Nc2nc(-c3ccc(C)cc3)n[nH]2)cc1 +Cc1c(Cl)cccc1NC(=O)CNC(=O)CSc1ncn[nH]1 +CNC(=O)c1cccc(CSc2ncnc3sc(C)cc23)c1 +Cc1ccc2ncc(C(=O)N3CCC(n4cncn4)CC3)n2c1 +Cn1cnc(S(=O)(=O)NCC(=O)NCC2(C)CCCC2)c1 +Cc1ccc(NC(=O)c2ccoc2)cc1S(C)(=O)=O +CCCC1CCC(NC(=O)NCCC(=O)N(C)C)CC1 +Cn1cccc1CN(Cc1cccnc1)CC1CCCO1 +NC(=O)C1CCN(C(=O)NCCOc2cccc3ccccc23)CC1 +Brc1ccc(OCc2nc(-c3ccncc3)no2)cc1 +NC(=O)c1nnc2sc(-c3ccc(Cl)cc3)nn12 +CC(C)c1c(C(=O)Nc2nc[nH]n2)cnn1-c1ccc(F)cc1 +CCN(CC)C(=O)CCCNC(=O)c1c(Cl)cccc1Cl +O=C(c1cccc(F)c1)N1CCCCCC1c1ccco1 +O=C(Nc1ccc(C(F)(F)F)cc1)c1cn[nH]c1 +CN(CCO)c1c2c(c(C#N)c3nc4ccccc4n13)CCC2 +Cc1ccc(C(=O)N2CCC(C(=O)Nc3nccs3)CC2)cc1 +C#CCNC(=O)N1CCN(C(=O)c2cccc(O)c2)CC1 +Nc1ccc(F)c2ccnc(C(=O)Nc3ccccc3Cl)c12 +O=C(CSc1ccccc1)Nc1nnc(-c2ccco2)o1 +CC(C)(C)C(C#N)NC(=O)c1cc(N2CCCC2=O)ccc1Cl +CNc1cc(N2CCCC2CNc2cc(C)nc3ncnn23)ncn1 +O=C(Cc1csc(-c2cccs2)n1)N1CC(O)C1 +COCc1ncc(C(=O)Nc2ccncc2)c(N)n1 +CCC(=O)c1cc(F)ccc1OCC(=O)NC(C)(C)C +COCCNC(=O)c1ccc(NCc2cc3ccccc3[nH]2)nc1 +C#CCOC(=O)c1c(-c2c(F)cccc2Cl)noc1C +CN(C)C(=O)C1(C)CN(Cc2cncs2)CCO1 +Cc1ccc(NC(=O)NC2CCN(c3ccccc3)C2=O)c(F)c1 +Cc1ccccc1CN1CCN(C(=O)c2ccccc2F)CC1 +Cc1nc(-c2ccc(C(=O)NCc3ccc4c(c3)OCO4)cc2)no1 +COCCOCCn1c(=O)[nH]c2ccccc2c1=O +CC(C)(C)OC(=O)N1CCC(C(=O)NC(C#N)c2ccccc2F)C1 +Cc1nc(NC(=O)N2CCC(C(=O)c3ccccc3)CC2)oc1C +CCN(CCCn1c(=O)[nH]c2ccsc2c1=O)c1ccccc1 +CC(Sc1nncn1C)C(=O)Nc1cccc(C(F)(F)F)c1 +Cc1cccc(C(=O)N2CCN(C(C(N)=O)c3ccccc3)CC2)c1 +O=C(c1cccc2[nH]ncc12)N(Cc1ccsc1)C1CC1 +COc1ccc(OC)c(S(=O)(=O)Nc2ccc(C)cc2)c1 +CCOC(=O)N1CCN(C(=O)Cc2csc(-n3cccc3)n2)CC1 +COc1ccc(C2CCCN2C(=O)c2csc(NC(C)=O)n2)cc1 +FC(F)(F)c1ccccc1OCCN1CCCC2(C1)OCCO2 +Cc1nnc(-c2cn(CC(=O)Nc3ccccc3)c3ccccc23)o1 +C=CCOc1ccc(C(=O)Nc2ccc(O)cc2)cc1 +O=C(NCCCn1ccccc1=O)c1cc2cc(F)ccc2o1 +COC(=O)C(C)(N)c1ccc(F)c(Br)c1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)Nc1ccc(F)c(F)c1 +O=C(Cc1ccccc1O)NCCNc1cnccn1 +O=C(CSc1ccc(O)cc1)Nc1ccc(Cl)cn1 +CC(C)CCCCNC(=O)NC(C)c1ccncc1 +Cc1ccc(C(=O)NCc2ccco2)cc1S(C)(=O)=O +Cc1ncc(CNC(=O)N2CCCC2c2cccc(Cl)c2)s1 +CC(NC(=O)CCC(=O)N1CCCC1)C(=O)N1CCCCC1 +CCOc1c(Br)cnn(-c2ccc(C)cc2)c1=O +Cn1cc(C=Cc2nc3ccccc3c(=O)n2-c2ccccc2)cn1 +CCOC(=O)Cn1c(C)c(Br)c2ccccc21 +Cc1cccc(NC(=O)CN(C)C(=O)c2ccc(=O)n(C)n2)c1C +Cc1ccc(CN2CCC3OC(COCC4CC4)CCC32)s1 +CCc1ccc2nc(C)cc(C(=O)NCCCn3ccnn3)c2c1 +Cc1cc(C)cc(NC(=O)c2ncc3n2CCN(C)C3)c1 +CC(NC(=O)NCC(C)N1CCOCC1)c1cccs1 +c1cncc(-c2ncc(CN3CCCC(c4nccs4)C3)s2)c1 +CC(C)NC(=O)C1CCCN1C(=O)c1cc2ccoc2s1 +O=C(c1ccnnc1)N1CCC2(CC1)Cc1ccccc1CNC2=O +N#CC1(C(=O)N2CCn3c(COCC4CC4)nnc3C2)CC1 +CN(CC(=O)NCC1CC1)c1ccc(Cl)cn1 +CC(Sc1ccccn1)C(=O)NCCOc1ccc(F)c(F)c1 +Cn1nc(C(=O)N2CCN(Cc3ccccc3)CC2)ccc1=O +CN(C)c1cncc(OC2CC2)c1S(N)(=O)=O +CCCCn1c(=NC(C)=O)n(CC(=O)OCC)c2ccccc21 +NC(=O)C1CCCN(C(=O)c2cc(C3CC3)on2)C1 +COC(=O)Nc1cc(C(=O)OC)ccc1C(=O)OC +CN(C)C(C(=O)NCC(F)(F)F)c1cccc(F)c1 +CC(CC(=O)Nc1cccc(C(F)(F)F)c1)n1cccn1 +COCCC(C)NC(=O)Nc1ccc2ccn(C)c2c1 +COc1cc(CCNC(C)=O)ccc1OCc1ccccc1 +CCC(NC(=O)NC(C)c1ccccn1)c1ccncc1 +O=C(OC1CCCCC1=O)c1ccc(N2CCCS2(=O)=O)cc1 +COC(=O)c1cccc(C(=O)N(Cc2ccc(Cl)cc2)C2CC2)c1 +Nc1cc(CCC(=O)Nc2ccccc2)ccc1N1CCOCC1 +CCC1(O)CCN(C(=O)CCc2c(C)noc2C)CC1O +Nc1cc(Cl)ccc1C(=O)OCC(=O)NCc1ccccc1 +CCN(C)C(=O)c1cccc(-c2nc(-c3ccc(C#N)cn3)no2)c1 +COCc1ccc(S(=O)(=O)Nc2cc(C)ccc2C)cc1 +Cc1cc(C)n(-c2ccc(CNC(=O)CCc3ccsc3)cn2)n1 +CC(OC(=O)COc1ccc(C#N)cc1)C(=O)c1ccccc1 +CC(=O)c1nnn(CC(=O)Nc2cc(Cl)ccc2C)c1C +Cc1ccc(-n2nnnc2SCC(=O)Nc2ccccc2)c(C)c1 +CCN(CC)C(=O)CN1CCN(C(=O)Nc2cccnc2OC)CC1 +O=C(Nc1cc(-c2ccc(F)cc2F)no1)c1ccc(=O)[nH]c1 +N#Cc1ccc(-c2noc(CCc3ncc(-c4ccccc4)o3)n2)nc1 +CCNc1nc(C)cc(N2CCN(C(=O)c3cccc(C)c3)CC2)n1 +N#Cc1nnn(-c2nccs2)c1CCCOc1ccccc1 +O=C(Cc1ccc(-n2cccc2)cc1)Nc1ccc(F)cc1F +CCCCNC(=O)C(NC(=O)c1cccs1)C(C)C +CCn1cc(C(=O)Nc2ccc(C(C)=O)cc2)cn1 +CC(C)CC(NC(=O)c1cccn1C)C(=O)OC(C)C +O=C(NCCc1ccco1)c1[nH]nc2c1CCCC2 +COc1cc(Cl)ccc1C(=O)NCC(=O)OC(C)(C)C +CCOc1ccc2cc(C(=O)Nc3ncccc3C)[nH]c2c1 +CC(Nc1ccc(C(N)=O)cc1)c1ccc(O)cc1 +Cc1cccc(Nc2nc(N)nc(CN3CCOCC(O)C3)n2)c1 +COc1ccnc(NC(=O)c2cccc(NC(=O)NC3CC3)c2)c1 +Cn1c(N)nnc1SCc1noc(-c2ccc(Cl)cc2)n1 +O=C(c1ccco1)n1nc(-c2ccco2)nc1NCc1ccccc1 +CCCC1CCC(NC(=O)Cc2ccc(NC(C)=O)cc2)CC1 +O=C(c1cccs1)N1CCCC1c1ccsc1 +COC(CNC(=O)C(C)Oc1ccccc1)c1ccsc1 +Cc1cc(NC(=O)c2cc3ccccc3s2)n(C)n1 +CC(C)Oc1ccc(C(=O)N2CCc3nncn3CC2)cc1 +COC(=O)C(C)NC(=O)CN(C)C(=O)c1cccs1 +Cc1cccc(OCCCCC(=O)Nc2ccnc(C)c2)c1 +CC(=O)c1ccc2c(c1)N(CC(=O)NC1CCCC1)C(=O)C(C)(C)O2 +CC1(C)CCC(CC(=O)Nc2ccc3[nH]nc(C(N)=O)c3c2)CC1 +O=C(CSc1ccc(F)cc1)NCC1CCCO1 +CCCSc1nc2c(c(=O)n1CC)SC(C)C2 +CCC(C)NC(=O)COc1ccc(Br)cc1C(C)O +Cc1c(CNC(=O)Nc2ccc(F)c(-n3nnnc3C)c2)cnn1C +CNS(=O)(=O)c1cccc(C(=O)NC2CCc3ccccc32)c1 +Cn1c(CCNC(=O)c2scnc2C2CC2)nc2c(F)cccc21 +Cn1c(C2CCN(Cc3ccc(CO)o3)C2)nc2ccccc21 +O=C(NCC(C1CCOC1)N1CCOCC1)c1ccc2c(c1)OCO2 +CN(C)C(=O)c1cc(C(=O)NC2CC2)ccc1F +Cc1nc2ccc(NC(=O)C3CC4CCC3O4)cc2s1 +Cn1ncc(-c2nc(-c3cccc(F)c3)no2)c1N +CCn1c(SCCC(N)=O)nc2sc3c(c2c1=O)CCCC3 +CCn1cnnc1CNC(=O)c1ccc2c(c1)CCC(=O)N2 +CC(NC(=O)NC1CCCC1Oc1ccccc1)C1CCOCC1 +O=C(CSc1nc(-c2ccccc2F)n[nH]1)Nc1cccc(F)c1 +COc1ccc(O)c(C(=O)c2cnc3ncnn3c2)c1 +O=C1CCc2cc(NC(=O)C3CCCN3C(=O)C3CC3)ccc2N1 +O=C(Cc1ccc(-n2cnnn2)cc1)NCc1ccccc1 +CCOc1ccccc1C(=O)Nc1ccc(CN2CCOC2=O)cc1 +Cc1ccc2cc(C(=O)NCC(C)(C)c3ccncc3)ccc2n1 +CC(C)C(=O)c1ccccc1NC(=O)CCSc1ccccn1 +CCOc1cc(F)ccc1NC(=O)NCCC(=O)N(C)C +CCCCCCNc1nc2nnnn2c2sc3c(c12)CCN(C)C3 +c1ccc(-n2cnnc2SCc2cn3cccnc3n2)cc1 +Cc1nc(-n2cccc2)sc1C(=O)N1CC2(COC(C)(C)OC2)C1 +N#CCSc1nnc(-c2ccc(Br)cc2)o1 +CC1CCC(NC(=O)CN2CCN(c3ccc(F)cc3)CC2)CC1 +Cc1cc(Cl)ccc1NS(=O)(=O)c1ccccc1N +CCNS(=O)(=O)c1ccc(C)c(C(=O)NCC2CCCO2)c1 +CCC1Oc2c(Br)cc(C)cc2N(C)C1=O +CCn1cc(Cl)c(C(=O)N2C(C)CCCC2C)n1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1cccc(Cl)c1OC +CCSc1nc2nnc3c(CC(=O)OC)nn(C)c3n2n1 +COc1ccc(-n2ccnc2-c2cc(C#CCO)cs2)cc1 +CCOc1ccc(-c2ccc(C(=O)NC)c(N)n2)cc1C +COc1ccc(CCN(C)C(=O)CO)c(OC)c1 +CC(=O)Nc1ccc(NC(=O)c2ccc3nnsc3c2)cc1 +CCc1noc(-c2ccc(SCC(=O)NCc3ccco3)nc2)n1 +Cc1cccc(S(=O)(=O)NCC(O)c2cn(C)c3ccccc23)c1 +CCCc1c(C(=O)N2CCCCC2)cnn1C(C)(C)C +Cc1cc(CN2CCN(C(=O)N(C)C)CC2)no1 +Cc1ccc(N2CCCN(Cc3c[nH]nc3-c3cccnc3)CC2)nn1 +CCc1onc(C)c1NC(=O)CCOc1ccc(C)cc1OC +COc1ccccc1C(=O)NCc1ccccc1C +COc1ccccc1C(=O)NCC(=O)c1ccccc1 +COc1ccc(C2=Nn3c(nnc3-c3ccco3)SC2)cc1 +COc1ccc(CNC(=O)CCc2cccc(N)c2)cc1 +Cc1cc(C)cc(NC(=O)Cc2nc(CO)cs2)c1 +O=C(Cc1n[nH]c(=O)c2ccccc12)NCCn1ccc2ccccc21 +CC(NC(=O)NCC(O)c1ccco1)c1ccncc1 +CCN(C(=O)CS(=O)(=O)c1nccs1)C1CC1 +Cc1cccc(N2CCN(c3cccc(N)c3)CC2)c1C +COc1ccccc1C(=O)N1CCCC1c1cc(C(C)C)on1 +CCOc1ccc(F)c(C(=O)N2CCN(C(=O)CC)CC2)c1F +O=C(Nc1ccc(-n2nncc2-c2ccco2)cc1)c1ccc(F)cc1 +CC(NC(=O)c1n[nH]c(=O)[nH]1)c1nc(C(C)(C)C)no1 +O=C(C1CCOCC1)N1CCc2onc(-c3ccccc3)c2C1 +CCc1nnc(-c2cccn2CC(=O)Nc2cc(Cl)ccc2C)o1 +CCOc1ccc(C(=O)N2CCC(c3cc(C)n[nH]3)CC2)cn1 +CCC(C(=O)Nc1ccc(F)cc1)N1C(=O)CCn2nc(C)cc21 +COC(=O)Cc1ccccc1NC(=O)C1COc2ccc(F)cc2C1 +Clc1cccc(-c2cnnc(NCCc3cnccn3)n2)c1 +COC(=O)C(C)NC(=O)c1nccc2ccc(N)cc12 +COc1ccccc1N(C(C)=O)S(=O)(=O)c1ccc(Cl)cc1 +COc1ccc(C(=O)CCC(=O)N2CCOCC2C2CC2)cc1F +CCN(C(=O)c1cccc(-n2cnnn2)c1)c1cccc2ccccc12 +Cc1cc(NC(=O)C2(c3cc(-c4ccccc4)on3)CC2)no1 +CC1(C(=O)Nc2ccc3c(c2)CCC3)CC1(Cl)Cl +COc1cc(N)c(C(=O)N(C)C2CCCCC2)cc1OC +COc1cc(-n2cnc3ccccc3c2=O)ccc1N +CCc1ccccc1-n1cnnc1SCC(=O)Nc1nccs1 +COc1ccc(Cl)c(NC(=O)c2cnc(C3CCCO3)s2)c1 +CCCC(=O)Nc1sc(C)c(C)c1C(=O)OCC +Cc1cc(Br)ccc1OCC(=O)NCc1ccncc1 +CCc1ccc2c(c1)nc(CCCO)n2CC(C)C +CC(C)c1ncncc1C(=O)N1CCOC(c2ccc(F)cc2)C1 +c1ccc(-c2n[nH]c3c2CN(Cc2cccc4c2OCO4)CC3)cc1 +CCn1c(NC)nc2c1c(=O)n(C)c(=O)n2CC +CCC1CCCN(C(=O)Cc2cccc(OC)c2)C1 +CCC1CCCCN1C(=O)CN1CCN(c2ccccc2)C1=O +COc1cccc2c1OCC(NC(=O)N(C)Cc1cc(C)on1)C2 +CCCN(C)C(=O)c1cc2sc(N(C)C)nc2s1 +COc1ccc(-c2nnc(NC(=O)C(C)C)s2)cc1 +CC1CCCCN1C(=O)c1ccc(Cn2nnc3ccccc32)cc1 +COc1ccc(C)cc1NC(=O)C(C)Oc1ccc(C(C)=O)cc1 +Cc1cc(CNC(=O)Nc2ccncc2)cc(C)c1O +CC(=O)c1cccc(OC(=O)Cn2cnc3c(C)cccc3c2=O)c1 +Cc1cccc(OCC(=O)NCCc2nc(-c3ccccc3)no2)c1 +Nc1ccnc(C(=O)Nc2ccc(F)cc2Br)c1 +CC(C)S(=O)(=O)N1CCCC(CNS(C)(=O)=O)C1 +CCCn1c(=O)c2c(nc3oc(C)c(C)n32)n(C)c1=O +Cc1ccc(CC(=O)Nc2cccc(Oc3ccc(C#N)cn3)c2)cn1 +CC(NC(=O)CCOc1cccc(Cl)c1)C(N)=O +Nc1ccc(Cl)c(C(=O)Nc2cc(Cl)ccc2F)c1 +O=C(CNC(=O)c1ccccc1Cc1ccccc1)NCc1ccco1 +CCOC(=O)C1(CC(F)F)CN(Cc2ccccc2)CCC1=O +CNC(=O)c1ccc(NC(=O)CN(C)C(C)=O)c(C)c1 +O=C(NCC1(c2ccccc2)CC1)Nc1cccc2c1OCCO2 +Cc1cc(Br)c(S(=O)(=O)n2ccnc2C)cc1Cl +CCc1cc2c(=O)[nH]c(-c3ccc(S(N)(=O)=O)cc3)nc2s1 +NC(=O)NCc1ccc(NC(=O)Cc2cccc3cccnc23)cc1 +O=C1NC(c2ccc(O)c(Cl)c2)Nc2ccccc21 +Cc1nccn1Cc1cccc(CNC(=O)N2CCNC(=O)C2)c1 +CC(=O)Nc1cc(Cl)ccc1NCC(=O)N1CCC(C)CC1 +COCCN1CCN(C(=O)c2cccs2)CC1 +CC(=O)N(C)Cc1cccc(NCc2ccc(Br)cc2)c1 +COC(=O)c1ccc(C)c(NC(=O)c2ccc(=O)n(C)n2)c1 +CCc1ccc(C(COC)NC(=O)Nc2cnccc2C)o1 +CC1CN(C(C)c2nnc(-c3cccs3)o2)CC(C)O1 +COCC1CCN(c2nc3nonc3nc2N2CCCCCC2)CC1 +Cc1nn(CC(=O)NCc2ncc3c(n2)CCC3)c(=O)c2ccccc12 +CN(Cc1cccs1)C(=O)C1(C)Oc2ccccc2NC1=O +CC(C)CCS(=O)(=O)N1CCN(C(C)C(=O)N2CCCC2)CC1 +Cc1cc(C)n(-c2cc(NCc3ccccn3)ncn2)n1 +CCCNc1nc(-c2ccc(=O)n(CC(C)C)n2)cs1 +COC(=O)c1sc(NC(=O)c2cc(Cl)c[nH]2)nc1C1CC1 +CCN(CC)C(=O)CSc1nnc2[nH]c(=O)c3c(n12)CCCC3 +COc1cc(N2CCC3C2CCN3C(=O)c2cnoc2C)ncn1 +Nc1cccc2oc(=O)n(CC(=O)OC3CCCC3)c12 +CS(=O)(=O)NCC(=O)N1CCc2cc(F)ccc2C1 +CC(=O)Nc1ccc(NC(=O)C2COc3ccc(F)cc3C2)cc1 +CC(=O)NC(C(=O)N1CCN(c2ccccc2F)CC1)C(C)C +CCc1nc(CC(=O)Nc2cc(Cl)ccc2C(=O)NC)cs1 +O=C(CSc1nc(=O)[nH]c2c1CCCC2)Nc1ccccc1F +CC(C)n1ccc2nc3ccn(-c4ccccn4)c(=O)c3cc2c1=O +Cc1ccc(CC(=O)N(Cc2cccnc2)CC2CCCO2)s1 +O=C(Nc1cc(C(F)(F)F)cc(C(F)(F)F)c1)c1cccnc1 +CCOC(=O)C1N=C(CCc2ccc(C)cc2)OC1=O +COc1cc(C(=O)Nc2cc(C)ns2)cc(OC)c1OC +CNC(=O)c1cccc(CCNC(=O)N(C)Cc2cc(C)on2)c1 +CCNC(=O)CN(C)c1ccc(C#N)c(Cl)c1 +Cc1noc(C)c1C(C)C(=O)NCC(C)(O)c1ccc(F)cc1 +Cc1noc2nc3c(c(C(=O)Nc4cccc(Cl)c4)c12)CCC3 +O=C(CCCOc1ccccc1F)Nc1nc(C(F)(F)F)n[nH]1 +C#CCN1CCN(C(=O)NCc2cn3cc(Cl)ccc3n2)CC1 +COC(=O)C1CCCn2nc(Cc3ccccc3OC)nc21 +CC(C)Cc1c(C#N)nnn1-c1nnc(C(C)C)s1 +Cc1ccc(CNC(=O)NC2C3CCOC3C23CCC3)s1 +Cn1ncc(N2CCC(CNC(=O)CCn3cncn3)CC2)cc1=O +Cc1nc(-c2c[nH]c(C(=O)N(C)CCC(F)(F)F)c2)cs1 +Cn1nc(C(=O)NCc2ccc(F)cc2)ccc1=O +CCNC(=O)Nc1ccc(-c2nnnn2C2CC2)cc1 +CCc1nc(Cn2cnc3sc(C)cc3c2=O)no1 +Cc1cccc(C(=O)N=c2[nH]nc3ccccn23)c1O +COc1ccccc1-c1noc(CSc2nncn2C)n1 +Cc1noc(C2CCCN(C(=O)CCC(=O)N3CCOCC3)C2)n1 +COCC(=O)N1CCCC1c1nc(N(C)C)ncc1-c1ccccc1 +CN1CCN(S(=O)(=O)Cc2cc(-c3ccccc3)no2)CC1 +Cc1cc(F)ccc1NCC(=O)Nc1ccccc1N1CCCC1=O +CC(=O)NCCCSc1nnc(Nc2ccccc2)s1 +O=C(NCC(NC(=O)C1CC=CC1)C1CC1)C1CC=CC1 +Oc1ccc2c(c1)nc(-c1ccncc1)n2-c1ccccc1 +Cc1nnc(NC(=O)C2CC(=O)N(C3CCCC3)C2)s1 +CNc1nc(-c2cnn(-c3ccc(C)cc3)c2C)cs1 +Nc1nc(C(=O)Nc2c(Cl)ccc3scnc23)n[nH]1 +COC(=O)c1ccc(NC(=O)NCC(C)(C)c2ccncc2)cc1 +Cc1ccnn1CC(=O)Nc1cnn(CC2CC2)c1 +CCC(C)c1ccc(S(=O)(=O)Nc2ccc(=O)n(C)c2)cc1 +O=C(Nc1ccn(CCc2ccccn2)n1)c1ccco1 +C#CCNC(=O)N1CCN(c2cccc(OC)c2)CC1 +COc1ccc(Br)cc1-c1nc(C)c(C)[nH]1 +Cc1noc(COCC(=O)NCc2cnn(C)c2)n1 +COc1ccc(CC(=O)OCc2c(C)noc2C)cc1OC +Cc1nc2ccc(NCc3cn(C)nc3-c3cccnc3)cc2s1 +O=C(Cc1ccc(N2CCCC2=O)cc1)OC1CCCCC1 +CCNC(=O)C(C)OC(=O)c1c(C)[nH]c2ccccc12 +CCc1nnc(Cn2nnc(-c3ccc(C(C)C)cc3)n2)n1C +Cc1cc(C)c(C(=O)N(C)c2nccs2)c(C)c1 +O=C(CNC(=O)NCc1ccc(F)cc1)NCc1cccc(Cl)c1 +O=C(Nc1cccc(Cn2cncn2)c1)c1n[nH]c2ccccc12 +O=C1CCN(C(=O)c2n[nH]c(=O)c3ccccc23)CC1 +O=C(c1ccoc1)N1CCC2(CCN2c2ncccn2)C1 +O=C(Nc1ccsc1)N1CCCC(c2nnc3n2CCCCC3)C1 +O=C(NCCN1CCOCC1)c1nc(N2CCCC2)ncc1Cl +COC(=O)c1ccc(CN2CC(=O)N3CCCCC3C2=O)cc1 +Cn1cnc(CNC(=O)N2CCCCCC2c2ccc(Cl)cc2)n1 +COc1cc(C#N)ccc1OCC(=O)NC1(C#N)CCCC1 +COc1ccc(C(=O)OCC2CCCCO2)cc1OC +CCN(C)S(=O)(=O)c1c(C)nn(Cc2cccc(C)c2)c1C +Nc1nc(-c2ccco2)ncc1C(=O)NCC1CCCO1 +Nc1cnn(CCOc2cc(Cl)ccc2Cl)c1 +O=C(NCc1cn[nH]c1)c1cc(-c2ccco2)on1 +Cc1cncc(N(C)Cc2ccccc2Br)n1 +Cc1nc(C)c(CC(=O)Nc2ccc(C(N)=O)cc2)c(=O)[nH]1 +O=C(c1ccc(-n2ccnc2)nc1)N1CCCC(c2ccccc2)CC1 +CC(C(=O)Nc1ccc(F)cc1)n1nnc2ccccc21 +CN(Cc1ccc(C(N)=O)cc1)C(=O)n1ccnc1 +CC(C)COc1ccccc1NC(=O)N1CCNC(=O)C1 +COc1ccc(OCCn2c(N)nnc2SCC#N)cc1 +CCOC1COC2(CCN(C(=O)c3ccc(OC)c(F)c3)CC2)C1 +CC(=O)NCCCCCC(=O)N1CCC(C)CC1C +COc1ccc(CN(C)C(=O)COc2cc(C)ccc2F)cc1 +CCCNC(=O)NCc1ccc2cc(OC)ccc2c1 +CC(C)CN1CCOC(COC(=O)c2cnn(-c3ccccc3)n2)C1 +O=C(NCCNC(=O)C1COc2ccc(F)cc2C1)c1ccco1 +COCCCNc1ncnc2c1cnn2-c1ccccn1 +O=C(NCC(O)C1CCCCC1)c1cc2ccccc2oc1=O +Cc1ccc(C(=O)NCc2cn3ccccc3n2)c(=O)[nH]1 +CC1CCC(C)N(C(=O)Nc2ccc(C(N)=O)nc2)C1 +N#Cc1nc(C2CCCCC2)[nH]c1-c1ccccn1 +Cc1cc(C(=O)N2CCC3C2CC(=O)N3Cc2csc(C)n2)[nH]n1 +Cc1noc(C(C)NC(=O)COCc2ccccc2Cl)n1 +CCc1nc2n(n1)CCCC2NC1=NS(=O)(=O)c2ccccc21 +Cc1cc(-n2ccnc2SCCO)ccc1Br +Cc1cc(C(=O)NCCCOCC(C)C)ccc1F +CN(C)c1cccc(C(=O)N2CCN(c3ccccc3Cl)CC2)c1 +Fc1cc(-c2ccncc2)ccc1CN1CCOC2(CCC2)C1 +COc1ccccc1NC1CCN(C(=O)Nc2ccncc2)CC1 +Cc1ccc(C(C)NC(=O)c2ccc(Cl)c3cccnc23)o1 +COc1cccnc1NC(=O)C1C2CC3CC(C2)CC1C3 +Cc1cc(N2CC3CCC(C2)N(CC2CCC2)C3=O)nc(N)n1 +COC(=O)CNC(=O)C(c1ccccc1)N1CCCC1 +Nc1ccc(C(=O)NCc2nc(-c3ccc(O)cc3)n[nH]2)cc1 +O=C(NCC1CCCCO1)Nc1ccc(Br)cc1F +Cc1noc(C)c1CCC(=O)N(C)C(C)c1cccs1 +CN(Cc1ccc(F)cc1)C(=O)c1cc2occc2n1C +O=C(Cc1noc(-c2cccs2)n1)NC1CCCC1 +COC1CCCN(C(=O)NCc2ccnc(OC3CCC3)c2)C1 +Nc1ccccc1S(=O)CCCOCC(F)(F)F +CCC(Cc1ccccc1)NC(=O)c1cc(S(N)(=O)=O)oc1C +CC1CC(C)CN(C(=O)c2ccccc2CC#N)C1 +Cc1nn(Cc2ccc(C#N)cc2F)c(C)c1CCO +Cn1c(=O)ccn(CC(=O)N(Cc2ccco2)C2CCCC2)c1=O +O=C(NCC(F)(F)F)c1cc(Cl)ccc1Br +CCOC(=O)c1cc(OC2CCC2)c(F)cc1N +CC(c1ccc(F)c(F)c1)N1C(=O)c2ccccc2S1(=O)=O +COc1ccc(CN(C)C(=O)c2cnc(C)cn2)c(OC)c1 +COC(=O)c1c(C)[nH]c(C(=O)COC(=O)c2ccccn2)c1C +COc1ccc(C(NC(=O)c2cc(C)on2)C2CCOCC2)cc1 +Cc1ccccc1N1CCN(S(=O)(=O)Cc2ccccc2)CC1 +O=C(NCCOc1ccc(-c2ccccc2)nn1)c1cccc(F)c1 +Cc1cc(CS(=O)(=O)c2nc(C)c(C)n2CC(C)C)no1 +CC(C)C(=O)N1CCC(C(=O)Nc2cc(-c3ccccc3)on2)CC1 +O=C(Nc1ccc2[nH]ncc2c1)c1n[nH]c2ccccc12 +Cc1ccc(-c2c(C(C)C)c[nH]c(=O)c2C#N)cc1 +CCn1c(-c2ccccc2)c(C(=O)CC#N)c2ccccc21 +O=C(NCc1nnc2n1CCC2)NC1CCC(O)CC1 +CNC(=O)NCC(=O)NCC(C)(C)c1cccc(Br)c1 +Cc1nc(C2(NC(=O)c3cc(F)c(F)c(F)c3F)CCCC2)no1 +O=C(CSc1ccccc1F)NCCOc1ccccc1 +Cc1ccc(CN(CC2CCCO2)C(=O)NCc2ccc(F)cc2)o1 +CC(O)CN1CCN(C(=O)c2cnn(-c3ccccc3F)c2)CC1 +CCOCCC(=O)Nc1c(C(C)C)cccc1C(C)C +O=C(NC1(c2ccc(F)cc2F)CCCC1)C1CCOCC1 +Cn1cc(C(=O)NC2CCc3cc(F)ccc32)c(C(C)(C)C)n1 +CC(c1ccncc1)N(C)C(=O)Cn1nnc2ccccc2c1=O +Cc1ccccc1CN(C)C(=O)c1cccc(OCC(F)F)n1 +Cc1ccc(C(O)C(C)NCc2ccc(F)cc2)cc1 +CC1(C)COCCN1c1cccc(Cl)c1C#N +CC(=O)Nc1ccc(C(=O)OCc2ccc(C)cc2)cc1 +O=C(c1ccncc1)N1CC2CCC(C1)N(Cc1ccccc1)C2=O +CN(C)C(=O)Nc1ccccc1C(=O)N(C)Cc1ccccc1 +CCS(=O)(=O)NCCNC(=O)c1ccc(C)s1 +CNC(=O)C(CC(C)C)NS(=O)(=O)c1cc2ccccc2o1 +N#Cc1ccc(NC(=O)c2ncn(-c3ccccc3)n2)cc1Cl +CCc1cnc(CNC(=O)Nc2cccc3[nH]ccc23)s1 +O=C(Cn1sc2cc(F)ccc2c1=O)NCc1ccccc1 +CSc1ccc(CN(C2CC2)C(F)(F)F)cc1 +Brc1ccccc1-c1nc2c3cn[nH]c3ncn2n1 +Cn1nccc1C(=O)Nc1ccc2scnc2c1 +O=C(CSc1nccn1C1CC1)N1CCCCCC1 +O=C(Nc1ccc(Cl)cc1)NC1COC2C(O)COC12 +Cc1noc(C)c1C(C)NC(=O)c1cc(F)c(F)cc1Cl +CSc1cccc(NC(=O)c2c[nH]c3ccccc23)c1 +COCC(=O)N1CCN(c2ccc(F)c(Cl)c2)C(=O)C1C +Cc1nc(CSc2ncnc3nc[nH]c23)nc2ccccc12 +Cc1nn(C)c2cn(C(C)C(=O)NCc3ccc(F)cc3)nc12 +CC(=O)c1ccc(NC(=O)Nc2ccc(C(C)=O)cc2)cc1 +CCOC(=O)c1cc2ccc(=O)c3c(C)oc(C)c3c2oc1=O +O=C(Nc1cnn(CC(F)F)c1)c1cccc(Br)c1 +Cc1ccc(C(=O)NCCCN(C)S(C)(=O)=O)c(=O)[nH]1 +Cc1nc(C2CCCN(C(=O)Cc3csc(C)n3)C2)cc(=O)[nH]1 +Cc1ccc(S(=O)(=O)NC(=O)c2ccc(Cl)cc2)cc1 +Cc1nn(C(C)(C)C)c2nc(C(C)C)cc(C(=O)NC(C)(C)C#N)c12 +COC(=O)c1ccc(Cn2ccnc2CC(C)C)cc1 +O=C(NCCC(=O)N1CCOCC1)c1cccc2ccoc12 +Cc1ccc2nc(-c3ccc(NS(C)(=O)=O)cc3)cn2c1 +Cn1ccc2ccc(NC(=O)CCC(=O)c3cccs3)cc21 +COc1ccc(S(=O)(=O)NCC2CCOC2)cc1C(N)=O +Cc1ccc(N(CC(=O)NCc2cccnc2)S(C)(=O)=O)cc1C +COc1ccc(C(=O)NCC(O)c2ccccc2OC)cc1 +COC(=O)c1ccccc1OC(=O)Cn1c(=O)n(C)c2ccccc21 +CCN1CCc2nc3cc(C)cc(C)c3c(C#N)c2C1 +Cn1cc(-c2nnn3c2COC(CNC(=O)c2cscn2)C3)cn1 +C=CCNC(=O)CSc1nc2sccc2c(=O)n1C +Cc1cc(C(=O)OCC(=O)Nc2ccc(C(F)(F)F)cc2)c(C)o1 +CCc1onc(C)c1NC(=O)Cc1ccc(NC(=O)C2CC2)cc1 +CCCOc1ccccc1-c1ccc(N)c(=O)n1C +COc1ccccc1C(=O)Nc1cc(C)cc(C)n1 +N#Cc1ncc(Br)c2cccc(F)c12 +Cc1ccccc1SCC(=O)OCC(=O)Nc1ccc(C#N)cc1 +Cn1nnc2c(SCC(=O)N3CCCc4ccccc43)ncnc21 +CCn1nc(C(=O)Nc2ncc(C)s2)c2ccccc2c1=O +CCOc1ncccc1-c1noc(CN2CCOCC2)n1 +O=C(Nc1ccc(F)cc1)c1cc(-c2ccc(F)cc2)[nH]n1 +Cc1ccc(CNC(C)C(=O)NC(C)(C)C)c(C)c1 +N#Cc1cc(NC(=O)Cc2ccc[nH]2)ccc1OCC(F)(F)F +C=CCN(Cc1ccccc1F)C(=O)Nc1ccnn1C(C)C +CC(Sc1nncn1C)C(=O)NC1(c2cccc(Cl)c2)CC1 +COCCN1CCN(Cc2coc(-c3cccc(F)c3)n2)CC1=O +O=C(CCCc1cccs1)Nc1ccc(CN2CCOC2=O)cc1 +CCN(CC)C(=O)CN(C)S(=O)(=O)c1cc(C)sc1C +CC(C)(C)C(C#N)NC(=O)Cc1ccc(F)cc1F +O=C(Nc1ccc2c(c1)C(=O)NCC2)c1ccccc1Cl +CCC(C)OC(=O)C1=C(C)NC(=O)NC1c1ccccc1 +CCOC(=O)n1c(=O)[nH]c2ccc(Br)cc21 +C#CCOc1ccccc1OCc1cccc(C(=O)NC)c1 +Cc1cc(C)n2nc(SCC(=O)Nc3ccc(Cl)cn3)nc2n1 +O=C(C1CC1)N1CCN(c2nc3ccc(Cl)cc3s2)CC1 +Cc1cc(C)cc(-n2nc(C)c(Br)c2N)c1 +O=C(Nc1nnc(Cc2ccccc2)o1)c1cc(-c2ccco2)on1 +O=C(Cn1cncn1)Nc1cccc(-c2nccs2)c1 +O=C(Nc1c(F)cccc1F)c1cnc(C2CCCO2)s1 +COc1ccc(C(C)=O)cc1CC(=O)Nc1ccc2c(c1)OCO2 +Cc1cc(C(=O)Nc2sc3c(c2C(N)=O)CCC(C)C3)no1 +CC1CN(S(=O)(=O)CCNC(=O)Nc2ccn(C)n2)CC(C)O1 +CCn1c(SCCCc2cnn(C)c2)nc2ccccc21 +CC(C)OCc1c(C(=O)N2CC(CO)OCC2C)oc2ccccc12 +COc1ccc(-n2nnc(C#N)c2-c2cccc(F)c2)cc1 +COc1ccc(C)cc1-c1cc(C#N)nn1CC(O)CO +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)CCCC(=O)N(C)C +Cc1noc(COC(=O)c2ccccc2-c2nnc(C)o2)n1 +CC(C)C(C)NC(=O)c1cnc(C2CCCO2)s1 +O=C(CN1CCOCC1)Nc1ccc(NC(=O)c2cscn2)cc1 +CC(C)(C)C(=O)N1CCC(C(=O)NCCNc2ncccn2)CC1 +COCCN(CCOC)C(=O)c1cc2cc(F)ccc2[nH]1 +CC1CCCN(S(=O)(=O)N2CCCC2c2ncc[nH]2)C1 +O=C(CC(F)(F)F)NCC(=O)c1cccc2ccccc12 +COC(=O)CCNc1ccc(Br)cn1 +O=C(c1cscn1)N1CCCCc2ccccc21 +CCOC(=O)c1sc2nc(C)nc(NCC3CC3)c2c1C +COC1CCN(C(=O)Cc2ccsc2)C1Cc1ccncc1 +Cc1cccc(NCC(=O)Nc2cccc(C(N)=O)c2)c1C +COC(=O)C1=C(C)NC(=O)NC1c1sc(C)nc1C +O=C(COc1ccccc1)NCCC(=O)N1CCCc2ccccc21 +CC(=O)Nc1cc2ccccc2cc1C(=O)NCCN1CCOCC1 +Cc1cc(Br)ccc1C(=O)N1CCC(=O)CC1 +Cc1ccccc1C(=O)NC1CCCc2occ(C)c21 +COc1ccc(NC(=O)C(C)C)cc1OCC1CCCO1 +Cc1ccc(C)c(NC(=O)CN(C)C(=O)C2CC2)c1 +Nc1c[nH]nc1C(=O)Nc1cnc2ccccc2c1 +CCn1cc(NC(=O)NCC(O)(CC)CC)cn1 +O=C(NCc1ccccc1N1CCCCC1)c1ccncc1 +CC(=O)c1cccc(NCC(=O)Nc2ccccc2C(C)=O)c1 +CC(C)(C)CN(CC(F)(F)F)C(=O)c1cccc(-n2cccn2)n1 +CCc1cc(N(CC)C2CCC2)nc(-c2ccccn2)n1 +O=C(NCCSc1ccccc1)NCC1COc2ccccc2O1 +CC(C)n1nccc1NC(=O)c1cc2cc(Cl)ccc2o1 +COc1ccc(S(=O)(=O)N(C)Cc2ccco2)c(C)c1 +COC(=O)c1sc(NC(=O)C2(C#N)CCC2)nc1C1CC1 +O=C(Nc1ccc(S(=O)(=O)C(F)F)cc1)N1CCCC(CO)C1 +CCc1c(-c2nnc(SCC(=O)OC)n2C)csc1C +Cn1c(=O)[nH]cc(CC(=O)NCc2cccnc2-n2ccnc2)c1=O +Cc1ccc2oc(=O)n(CCOc3ccc(N)c(C)c3)c2c1 +COc1cc(CN2CCc3[nH]nc(-c4ccccc4)c3C2)cc(OC)c1 +CC(=O)C(NC(=O)CN(C)c1ccccc1)C(C)C +O=C(c1csc(N2CCN(c3ccccc3)CC2)n1)N1CCCC1 +Cc1cc(NC(C)C(=O)Nc2ccccc2)ccc1NS(C)(=O)=O +O=C(NCc1nnc2n1CCC2)N(Cc1cccs1)C1CC1 +Cc1csc(-n2nnc(CO)c2C2CCCCC2)n1 +CCNC(=O)NC1(C(=O)Nc2ccc(-n3cncn3)cc2)CCCC1 +C=CCCCN(C)C(=O)c1cnn(C(C)C)c1C(F)(F)F +O=C(CCc1c(-c2ccccc2)nc2ccccn12)NC1CC1 +CCOC(=O)N1CCCC(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)C1 +COc1ncccc1C(=O)N1CCCC(c2cc(C)[nH]n2)C1 +CCC(OC)C(=O)Nc1ccc(N2CCOC2=O)cc1 +COC(=O)c1ccc(-c2nc(C3CC3)nn2-c2ccccc2)nc1 +CNc1cc(C(=O)NCc2csc(N(C)C)n2)ccn1 +Cc1nc(C)c(C(=O)NCCCn2ncccc2=O)s1 +O=C(NCc1ccc(F)cc1)C1CC(=O)N(c2cc(F)cc(F)c2)C1 +Cc1ccc(C(=O)N2CCC(C(=O)N3CCCC3)CC2)cc1 +Cc1cccc(-c2[nH]ncc2CN2CC3OCCN(C)C3C2)c1 +COc1ccccc1C1(CNC(=O)C2CC(=O)N(C)C2)CCCC1 +CC1CC1NC(=O)c1ccc(OCC(F)F)nc1 +CC(C)Oc1ccc(CNC(=O)N(C)Cc2ccccn2)cc1 +Oc1ccc(C2CCN(c3ncccn3)CC2)cc1 +Cc1cccnc1CNC(=O)c1cccc(-c2cn[nH]c2)c1 +O=C(CCNS(=O)(=O)c1ccc(F)c(F)c1)Nc1nncs1 +Cc1cnc(C(=O)N2CCN(CC(O)C(C)(C)C)CC2)cn1 +CC(C)=CCCC1(C)CCC(=O)N(CCn2ccc(C)n2)C1 +CCCCNC(=O)Cn1c(-c2cccc(Cl)c2)nc(C)cc1=O +Cc1nc2ccccc2n1CCNC(=O)N(C)CC1CC1 +CNC(=O)C1CN(C(=O)c2ccc(C#N)cc2)CC12CCCC2 +CC(O)c1nc2cc(N)ccc2n1-c1ccncc1 +COC(=O)C(Sc1ccccn1)c1ccc(C#N)cc1 +Cc1nnc(N2CC(C)OC(c3ccsc3)C2)c(C#N)c1C +COc1nc2c(cc1-c1nc(-c3ccncc3)no1)CCC2 +COc1ccc(C)cc1Nc1nc(C(=O)N2CCNC(=O)C2)cs1 +CN(Cc1nc2ccccc2c(=O)[nH]1)c1ncccn1 +O=C(Nc1cccc(F)c1)c1ccc(N2CCOC2=O)cc1 +Cc1ccc(C)c(C(C#N)CCC(=O)N2CCCC2)c1 +COc1cccc2[nH]c(C(=O)NCCC(=O)NCc3ccco3)cc12 +Clc1cccc(-c2csc(N3CCOCC3)n2)c1 +Cn1cccc1C(=O)N1CCC2(CC1)CN(CC1CC1)c1ccccc12 +CC(NC(N)=O)C(=O)NC(c1ccc(Cl)cc1)C1CCCC1 +Cc1nc(CNC(=O)N(CCO)C2CC2)oc1-c1ccc(Cl)cc1 +Cc1ccccc1CNC(=O)CCc1nc2ccccc2c(=O)[nH]1 +O=S(=O)(NCCOc1cccc(F)c1)N1CCOCC1 +COc1ccc(OC(C)C(=O)Nc2cc(-c3cccs3)n[nH]2)cc1 +CCC(C)NS(=O)(=O)c1ccc(NC(=O)C2CC2)cc1 +CCCc1nc(N2CCCC(CC)(CO)C2)c2cnn(C)c2n1 +Cc1noc(CCC(=O)Nc2cccc(Cl)c2)n1 +CC(C)C(=O)NCCNS(=O)(=O)c1c(F)cccc1F +CCOc1ccc(S(=O)(=O)n2ccnc2)c(C)c1C +CCCOc1ccccc1C(N)C(=O)NCCO +Cc1csc(NC(=O)COC(=O)c2cc3c(s2)CCC3)n1 +O=c1c2c3c(sc2ncn1CC(O)CN1CCOCC1)CCCC3 +CC(=O)c1ccc(NC(=O)C(C)S(=O)(=O)c2ccc(F)cc2)cc1 +COCCNC(=O)c1cc(C2CC2)nc(SC)c1C#N +Cn1c(=O)c2c(N3CCC(C(N)=O)CC3)ccnc2n(C)c1=O +Cc1nc(NC(=O)C(C)Sc2nncs2)sc1C +CNc1cc(S(=O)(=O)N2CCC(O)CC2)ccn1 +Fc1ccc2c(c1)CCN(Cc1coc(-c3cccs3)n1)C2 +CN(C(=O)c1ccc2c(c1)nnn2C)c1ccc(Cl)cn1 +O=C(Nc1ccccc1-n1cnnn1)c1cccc(N2CCCC2=O)c1 +CC(C)(C)OC(=O)CSc1n[nH]c(=O)n1C1CC1 +Cc1ccc(NCc2cc(Cl)cc(Cl)c2)cn1 +Cc1ncsc1CNc1ncccc1C(F)(F)F +Cc1ccc(-c2cc(C(=O)NC(C)(C)CO)no2)cc1 +O=C(CCCc1ccccc1)NCc1ccc(-n2cncn2)cc1 +COc1cccc(CCC(=O)OCc2nc(C)no2)c1 +Cc1ccc2c(=O)n(CC3CC(=O)N(C(C)C)C3)cnc2c1C +CCOCC1CCCN(C(=O)CSc2ccc(F)cc2)C1 +CCCCNC(=O)C(c1ccccc1)n1cnnn1 +CCCOc1ccnc2c1c(=O)n(CC#N)c(=O)n2C +COc1cc(NCc2nccn2Cc2ccccc2)ncn1 +CCc1noc(CC)c1CC(=O)N(CC1CCCO1)c1ccncc1 +O=C(C1COc2ccccc2O1)N1CCSc2ccc(Cl)cc21 +COC(=O)Nc1ccc(NC(=O)C2CC=CCC2)cc1F +CCc1nc(CC(=O)NC(C)c2ccc(F)cc2)cs1 +COc1ccc(CNC(=O)NCc2cn(-c3ccccc3)nn2)cc1 +O=C(Nc1ccc(-n2nccc2C(F)(F)F)cc1)c1cc[nH]n1 +C=CCn1c(=O)c(N2CCC(NC(=O)NC)CC2)nc2cccnc21 +CC(NC(=O)Nc1ccccc1)C(=O)N(C)Cc1ccncc1 +N#CCCn1ncc2c(NCCc3ccsc3)ncnc21 +CC1CN(C(=O)C2CCOCC2)c2ccc(F)cc2O1 +CC(C)Oc1ccc(C(=O)Nc2ccc(Cl)cc2C(N)=O)cn1 +CCN1Cc2nc(OC)c(CNc3ncnc4[nH]cnc34)cc2C1=O +O=C(Cc1ccccc1)N1CCC(Cc2cnc3[nH]ccc3c2)C1 +Cc1noc(C)c1CN(C)C(=O)NCC1CCN(C)c2ccccc21 +COCCN(CCC#N)Cc1cnc2cc(C)ccn12 +Cc1nc2c(c(=O)[nH]1)CCN(C(=O)c1cnc(N)nc1C)C2 +O=C(C1CC1)N1CCC(C(=O)N2CCCc3cc(F)cc(F)c32)CC1 +C#CCOc1ccc(C(=O)N(C)CC(O)COC)cc1 +O=C(Nc1ccccn1)C1(c2ccccc2)CCOCC1 +Cc1cc(C)cc(C(=O)NCC(=O)NCC(=O)Nc2nccs2)c1 +Cc1n[nH]cc1NC(=O)CCc1nc(C(C)(C)C)no1 +COc1ccc2c(c1)-c1onc(C(=O)NC(C)C(C)C)c1CC2 +CN(C)C(=O)c1nc2ccccn2c1-c1ccsc1 +CS(=O)(=O)N1CCN(C(=O)c2nnn(-c3ccccc3)n2)CC1 +CCN(Cc1cccc(NCc2ccsc2)c1)C(C)=O +COC(=O)C(NC(=O)c1ccc(C)cc1C)c1cccnc1 +CCC(CC)NC(=O)C(C)Sc1nnc(-c2cccs2)n1C +CC(=O)NCCCN(C)c1ncccc1-c1nc(C)no1 +COc1ccc(OC)c(CN(C)C(=O)c2ccc(F)cc2F)c1 +CCC(C)NC(=O)c1ccc(NC(=O)CNc2ccccc2F)cc1 +Cc1ccc(-n2nc(NC(=O)Nc3cnn(C)c3)cc2C)cc1 +Cc1noc(C)c1COC(=O)C(O)c1ccc(Br)cc1 +CCN(Cc1cccs1)C(=O)c1nn(-c2ccccc2)cc1OC +CC1CCN(C(=O)CCc2ccccc2O)C(C)C1 +CN(C)C(=O)Cn1c(N(C)C)nc2c1c(=O)[nH]c(=O)n2C +COCc1ccccc1CNC(=O)N1CC(C)c2ccccc21 +COc1ccc(C(=O)Nc2cccc(C#N)c2)c(OC)c1OC +COC(=O)c1ccccc1Cn1ccnc1-c1ccccn1 +CCn1c(C(=O)N(C)Cc2cccc(C#N)c2)cc2ccccc21 +COCC(NC(=O)c1cc(-c2ccccc2Cl)[nH]n1)C(N)=O +OC(c1ccccc1F)C1NCCc2cc(F)ccc21 +Cc1cc(C(=O)Nc2ccccc2)c(C)n1-c1nccs1 +O=S(=O)(NCCn1ccnc1)c1ccc(O)cc1 +CC(C)CCNC(=O)C1(C)Sc2ccccc2N(C)C1=O +Cc1csc2ncc(C(=O)NCCc3ccccn3)c(=O)n12 +CCOC(=O)c1cnn2ccc(NC(=O)c3ccccc3Cl)cc12 +COc1cc2nc(C=Cc3ccco3)oc(=O)c2cc1OC +CCc1cc(C(=O)N2CCCC(c3cc4ccccc4cn3)C2)on1 +CCS(=O)(=O)NCC(=O)N1CCN(c2ccccc2)CC1 +CCc1sc(C(=O)NCCc2nnc3n2CCCCC3)cc1C +CC(NC(=O)CSc1nnc(N)n1C)c1ccccc1 +CSc1nc2nc(C(C)C)c(-c3cccs3)c(N)n2n1 +Cc1cc2c(s1)c1cnn(CC(=O)NCC3CC3)c(=O)c1n2C +O=C(CCCCO)Nc1ccc(Cl)cc1C(F)(F)F +CC1(C)CN(C(=O)Nc2cccc(OCc3cccnc3)c2)CCO1 +Cc1cc(CN2CCC(CN3CCOCC3)C2)ccc1-n1cncn1 +CCC(C)C(=O)OCc1nccn1Cc1ccccc1 +O=C(CN1CCN(C(=O)CO)CC1)NCC1CC1 +CCNC(=O)c1ccc(NC(=O)N(C)CC2CC2)cc1 +C#Cc1cccc(N(CC(=O)NC)Cc2noc(C3CC3)n2)c1 +CCC(=O)N1CCCN(CC(=O)c2cc(C)n(CCOC)c2C)CC1 +COc1ccccc1-c1nc2c(F)cccn2c1CC#N +Cc1oc(C)c(C(=O)Oc2ccc3c(c2)CCC(=O)N3)c1C +CN(CCc1ccncc1)C(=O)NC1CCCc2ccc(F)cc21 +CC(C)(C)OC(=O)NCCNC(=O)NC1CCCCC1 +COc1ccc(CNc2ccccc2F)cc1OC +CC1Nc2ccccc2N(CC(=O)Nc2ccc(F)cc2)C1=O +CCN(CC)C(=O)c1ccccc1N1CCC(NC(=O)C(C)C)CC1 +CCC(=O)N1CCc2ccccc2C1C(=O)NCc1cccc(F)c1 +CCN(CC)C(=O)NC(C)C(=O)NCc1ccco1 +CCCNC(=O)C1CCN(C(=O)c2cc3ccsc3[nH]2)CC1 +COc1ccc(S(=O)(=O)Nc2ccc3[nH]ncc3c2)cc1OC +CC12CCC(C(=O)NCc3ccc4c(c3)OCO4)(CC1=O)C2(C)C +CCOc1cccc(NC(=O)CCc2nc(C)no2)c1 +CC(c1ccco1)N(C)C(=O)c1ccc(-n2ccnn2)cc1 +O=C(c1cc(-c2ccccc2O)no1)N1CCN(c2ccccc2)CC1 +Cc1noc(C(C)NC(=O)Nc2nnc(-c3ccccn3)s2)n1 +O=C(NCC(Cc1cccc(F)c1)N1CCNC1=O)c1ccccc1 +O=C(NCc1ccc(O)c(F)c1)c1c[nH]c(=O)c(Br)c1 +COc1ccc(OCCn2nnn(-c3cccs3)c2=O)cc1 +CCc1ccccc1OCC(=O)NCC(O)c1ccccc1Cl +CS(=O)(=O)NC1CCN(c2ncnc3sccc23)CC1 +Cc1cccc(OCC(=O)Nc2c(C)cc(N)cc2C)c1 +CCOc1ccccc1OC1CCN(C(=O)c2ccc(C)n2C)CC1 +Cc1noc(C)c1NC(=O)NCc1cccnc1OCC(F)(F)F +CCc1cccc(C)c1NC(=O)CNc1ccc(C(=O)N(C)C)cc1 +CC1(C)CN(C(=O)CCNC(=O)c2ccc(C(C)(C)C)cc2)CCO1 +CCOC(=O)CN(C)C(=O)c1ccc(F)cc1Br +Cc1cc(NC(=O)CNC(=O)c2c(F)cccc2Cl)ccc1O +Cc1ccc(-n2cnnc2SCC(=O)N2CCC(O)C2)cc1C +Cc1c(Cl)c(C(O)c2ccco2)cc2c1NC(=O)C2(C)C +CC(O)(CNCc1cccc(C#N)c1)c1ccsc1 +CCCC(NC(=O)Cn1cnnn1)C(=O)N1CCc2sccc2C1 +O=C(NCC1CN2CCCCC2CO1)Nc1ccc(F)c(F)c1 +Cn1cnc(CNC(=O)CSc2ccc3c(c2)CCC3)n1 +Cc1ccnc(C(=O)Nc2cccc(Cl)c2Cl)n1 +COc1ccccc1NC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +Cc1ccc(OCCNC(=O)N2CCC(C(N)=O)CC2)c(C)c1 +NC(=O)c1ccc(NC(=O)COc2ncnc3ccccc23)cc1 +COc1ccc(NC(=O)NCCO)cc1OCC(F)(F)F +COc1ccc(C(=O)C2CCN(C(=O)c3ccco3)CC2)cc1 +CCC(Oc1ccccc1OC)C(=O)NC1CCCCC1 +CNC(=O)NCC(=O)N1CCc2c(Cl)cccc21 +COCC(C)(NS(=O)(=O)c1c(F)cc(F)cc1OC)C(N)=O +N#Cc1ncn(CC(=O)NCc2ccc(-c3ccc(Cl)cc3)o2)n1 +CS(=O)(=O)N1CC(C(=O)N2CCCC2)Oc2ccccc21 +CC(NC(N)=O)C(=O)NCc1cccnc1OCc1ccccc1 +COc1ccccc1CNC(=O)c1cccc(C)c1C +CC(C)C(C)(C#CCN1CCOCC1)OCCC#N +CCn1c(=O)[nH]c2cc(C(=O)C(C#N)c3ccccn3)ccc2c1=O +CN(Cc1cc(C(C)(C)C)n[nH]1)C(=O)c1ccc(C#CC(C)(C)O)o1 +Cc1cc(CCNC(=O)CCC(=O)c2ccc(Cl)cc2)on1 +O=C(CN1CCCCC1=O)Nc1ccn(-c2ncccc2Cl)n1 +Nc1ccc(C(=O)OCCc2cccs2)cc1F +CCCn1nnc(NC(=O)c2ccc(OC)c(OC)c2)n1 +CCOc1ccc(CC(=O)N2CCNC(=O)C2(C)C)cc1 +CCN1CCc2c(cc(C#N)c(=O)n2CCC(C)C)C1 +CCC1Oc2cc(N)ccc2N(CCOc2cccc(C)c2)C1=O +N#Cc1ccc(NC(=O)Nc2ccc(Cl)cc2)nc1 +CN(Cc1cccs1)C(=O)CSc1nnnn1C +Nc1cc(=O)[nH]c(SCC(=O)c2ccc(O)cc2O)n1 +CCOC(=O)c1[nH]c(C)c(-c2csc(NC(=O)C3CC3)n2)c1C +CC(=O)NC(CC(=O)N1CCCC1c1ccc[nH]1)c1ccc(C)cc1 +CCC(CC)(CO)NC(=O)Cc1ccc(O)cc1 +O=C1CN(C(=O)Nc2nncs2)CCN1Cc1cccc(F)c1 +O=C(CSc1cc(Cl)ccc1Cl)N1CCNCC1 +CC(=O)c1cccc(S(=O)(=O)NC(C)c2ccccn2)c1 +O=C(NCCOc1ccc(C(F)(F)F)cn1)c1ccccn1 +COc1ccccc1-c1cn2c(C)c(C#N)ccc2n1 +Cc1ccc(CCC(=O)NCC(C)(C)C(N)=O)c(C)c1 +Cc1cccc(OCC(=O)NCc2nc(-c3cccc(C)c3)no2)c1 +COC(=O)c1c(C)[nH]c(C(=O)CN(C)Cc2ccccc2F)c1C +CC(C)Cc1cc(CNC(=O)c2scc3c2OCCO3)no1 +CCn1nc(C)cc1C(=O)n1nc(C)c(Sc2nccn2C)c1C +COC(=O)c1cncc(NCc2cccc(OC)c2OC)c1 +CCC(CC)C(=O)N1CCC(OCc2ccc(F)cc2)CC1 +Cc1nc2ccccc2n1CCNC(=O)Cc1noc2ccccc12 +CCC(C)NC(=O)N1CC=C(c2ccc(O)cc2)CC1 +CN(CC(=O)NCCNC(=O)c1cccs1)S(C)(=O)=O +CC(=O)NCC1CCCN(C(=O)NCCC(C)C)C1 +Cn1ccc(NC(=O)NCc2ccnc(OC3CCC3)c2)n1 +O=S(=O)(NCCCn1cnc2ccccc21)c1cccs1 +CC(=O)c1ccc(OCC(=O)NCC2CCCO2)cc1 +Cc1sc(=O)n(CC(=O)NCCc2c(F)cccc2F)c1C +Cc1ccc(F)c(S(=O)(=O)N2CCC(N3CCCC3=O)CC2)c1 +OCCc1cn(Cc2c(Cl)cccc2Cl)nn1 +O=C(NC1CCCCC1)c1cc(-c2ccncc2)c2cnccc2n1 +C#CCCOc1ccc(CN2CCNC(=O)CC2c2ccccc2)cc1 +CCNc1ccccc1S(=O)(=O)NCCS(N)(=O)=O +CN(CCO)C(=O)Nc1cccc(CN2CCCCC2=O)c1 +Cc1nnnn1-c1cccc(NC(=O)CCn2cncn2)c1 +Cc1noc(C)c1CC(=O)Nc1cccc(OCC(F)(F)F)c1 +CC(=O)N1CCN(CC(=O)N(C)Cc2ccco2)CC1 +COc1ccc(OCCNC(=O)Cc2c[nH]c3ccccc23)cc1 +CCc1noc(CC)c1CC(=O)N(C)c1ccc(OC)nc1 +CCn1c(SC(C)C(N)=O)nnc1-c1ccco1 +CNC(=O)NCC(=O)NCC1(c2ccccc2)CC1 +CSc1ccccc1NC(=O)Cc1ccc(N2CCCC2=O)cc1 +COC1CCCCC1OC(=O)c1cccc(NC(N)=O)c1 +O=C(COc1ccccc1F)NCc1ccccc1 +CC(C)C(C)N(C(=O)COc1ccc(C(N)=O)cc1)C1CC1 +CC(C(=O)N1CCCCC1)N1CCN(Cc2cc(C#N)cs2)CC1 +CN(C(=O)c1ccc(C#N)cc1)c1ccccc1F +O=C(C1CC(=O)N(c2ccccc2)C1)N1CCc2ccccc2C1 +CC1CN(S(=O)(=O)c2ccc(Br)cc2)C(C)CO1 +COCc1nsc(N2CCC(c3c[nH]c4ncccc34)CC2)n1 +CC(=O)Nc1ccc(F)c(NCc2cccc3cccnc23)c1 +CC(=O)NCC(=O)NCC(=O)NC(C)Cc1ccc2ccccc2c1 +FC(F)(F)Cn1cc(NCc2cnc(C3CCC3)s2)cn1 +Cc1nc2ccccc2n1CCCNC(=O)c1ccc(F)c(F)c1 +COc1cccc(C(=O)N2CCc3cc4ccccc4nc32)c1 +CC(C)C(NCc1ccccc1)C(O)c1ccccc1 +Cc1noc(C)c1CNC(=O)NC(C)c1cc2ccccc2o1 +Cc1nc2n(n1)CCCC2NC(=O)NC(C)Cc1ccco1 +COCc1ccc(C(=O)NCCc2cccc3cccnc23)cc1 +COc1cc2nc(C3CC3)n(C3CC3)c2cc1OC +Cc1ccc2nc(-c3nc4c([nH]3)CC(C)(C)CNC4=O)cn2c1 +CCOCCC1(C(=O)Nc2cc(OC)ccn2)CCC1 +Cc1sc(-c2ccco2)nc1C(=O)N1CCCC(O)C1 +Cc1csc(CSc2nnc(COc3ccc(F)cc3)o2)n1 +COc1ccc(C=Cc2nn3c(-c4ccccn4)nnc3s2)cc1 +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccccc1O +NC(=O)C1CN(c2cc(=O)n3ccccc3n2)CCN1 +Cc1cc(=O)cc(C2CCN(C(=O)c3cc(C4CC4)n[nH]3)CC2)[nH]1 +CCN(CC1CCOC1)C(=O)c1cc(C)c(OC(F)F)c(C)c1 +Cc1cc(C)n(CC(C)CNC(=O)N2CCOC(C)C2)n1 +Cc1nc(N(C)C)ncc1C(=O)NCCSc1nnnn1C +CSc1ccc(C(=O)Nc2nnc(-c3ccncc3)o2)cc1 +CCN(C)C(C(=O)NC(C)C(=O)N1CCCCC1)c1ccccc1 +COc1ccc(Cn2ncc3cc(C(=O)N(C)C)cnc32)c(OC)c1 +COC(=O)c1cc(C(=O)N2CCc3cc(F)ccc3C2C)ccn1 +O=C(NCCC(=O)N1CCCCCC1)c1ccc(F)cc1F +O=C(C1CCCO1)N1CCC2(CC(n3cnnc3)CO2)C1 +CN(Cc1ccc(C#N)cc1)S(=O)(=O)CCCCC#N +COCC1CCCN1C(=O)c1cccc(-c2ccoc2)c1 +Cn1cc(NC2CCOc3ccccc32)ccc1=O +Cc1ccsc1C(=O)OC(C)C(=O)Nc1ccc(Cl)cn1 +Cc1cc(C(=O)COc2ccc(C#N)c(F)c2)c(C)n1C1CC1 +CN(Cc1ccc2c(c1)OCCO2)c1nccc2c1C(=O)OC2(C)C +COc1ccc(C)cc1C(=O)NC1(C#N)CCOCC1 +CC(C)C(=O)c1cccc(S(=O)(=O)NC2CCCC2)c1 +O=C(Nc1ccc2c(c1)COC2)C1CC1c1ccc2c(c1)OCCO2 +COc1ccccc1NCc1ccc(OC)c(O)c1Cl +Cc1nscc1C(=O)NCCc1ccc(Cl)cc1 +CC(C)(C)c1nc(CNC(=O)N(CCO)Cc2ccccc2)cs1 +COc1ccc(-c2csc3nc(N)[nH]c(=O)c23)cc1C +COC(=O)c1ccccc1OCC(=O)NC1(C#N)CCCCC1 +Cc1ccc(C(=O)N2CCN(c3nccs3)CC2)n1C +C#CCNC(=O)c1ccc(OCc2cc(C)on2)c(Br)c1 +COc1ccc(CCNC(=O)C2CC2c2ccccc2)cc1 +Cn1c(=O)c2c(nc(NCCCc3ccccc3)n2C)n(C)c1=O +CCCN(C)c1cc2n(c(=O)n1)CCc1cc(OC)c(OC)cc1-2 +CCCCC(=O)c1ccc(S(=O)(=O)CC(=O)NC)cc1 +Cc1ccc2nncc(SCc3nnnn3C(C)C)c2c1 +O=C(CCn1c(CO)nc2ccccc21)NCC(F)(F)F +Cc1cc(CN(C)S(=O)(=O)c2cccc(Cl)c2F)no1 +Nc1ccc(Cl)cc1NC(=O)c1cccs1 +Cc1ccc(C(C)NC(=O)Cn2c(C)c(C)sc2=O)cc1 +CCCOc1ccc(OC(=O)C2CCCN(C(=O)CC)C2)cc1 +CNC(=O)c1ccc(CN(C)c2nccn3cnnc23)cc1 +CC(C)(C)C(=O)N1CCN(C(=O)C2CCCN(C(N)=O)C2)CC1 +O=C(N1CCCC1)N1CC2COCC2(COCc2ccccn2)C1 +COc1cc(NC(=O)c2cccc(OC)c2F)cc(OC)c1 +N#Cc1ncn(Cc2nc(-c3ccsc3)no2)c1C#N +N#Cc1nnn(CCCOc2ccc(Cl)cc2)c1C1CCC1 +CC(C)c1noc(CN2CCN(C(=O)c3cnns3)CC2)n1 +Cc1nn(C)c(N)c1S(=O)(=O)NCc1ccccc1 +CCCC(=O)Nc1ccc2c(c1)CN(S(=O)(=O)CCC)CC2 +CCn1cc(C(=O)NCc2cccc(NC(=O)c3ccncc3)c2)cn1 +CCOc1ccccc1-c1nc2ccc(CO)cn2c1N +CC(NC(=O)CC1C=CCC1)C(=O)NC(C)(C)C +Cc1ncc2c(n1)CCCC2NC(=O)c1cc(C(C)C)on1 +O=C(NCc1ccnc(OC2CCC2)c1)Nc1cccc2cccnc12 +COc1ccc(CCNC(=O)c2cn(CC3CCCO3)nn2)cc1O +CN(C)c1ccc(=NS(=O)(=O)c2ccc(C#N)cc2Cl)[nH]c1 +Cc1cc(C(=O)NCCNS(=O)(=O)c2cccc(Cl)c2)on1 +CCS(=O)(=O)NCCNC(=O)c1cc(C)ccc1O +Cn1cc(C(=O)OCCn2cc(Br)ccc2=O)cn1 +COc1cccc(C(=O)Nc2cccc(-c3nncn3C)c2)c1O +Cc1noc(C2CCCN2C(=O)c2ccc3cccc(Cl)c3n2)n1 +COc1ccc(CC(=O)Nc2cc(C(N)=O)cc(F)c2C)c(OC)c1 +NC(=O)COc1cccc(-c2cn(CC3CCOCC3)nn2)c1 +C=CCn1c(C)nnc1SCC(=O)Nc1cc(C)cc(C)c1 +CCC1CCC(NC(=O)c2cnc3sccn3c2=O)CC1 +CN(C)C1COCC1OC(=O)C(O)(c1ccccc1)c1ccccc1 +O=C(C1CCO1)N1CCCCC1c1nccs1 +CCN(CC(C)C#N)C(=O)COc1ccc(S(C)(=O)=O)cc1 +O=C(NCc1ccncc1)c1cc(=O)c2cc(Cl)cc(Cl)c2o1 +Cc1occc1C(=O)N1CCN(Cc2csc(C(C)(C)C)n2)CC1 +O=C(NCCN1CCc2ccccc21)c1cnn[nH]1 +O=C(NCCn1nc(-n2cccn2)ccc1=O)c1ccc(=O)[nH]c1 +CC(=O)Nc1ccc(CC(=O)N2CCCc3cc(C)ccc32)cc1 +Cc1nc(CN(C)c2nc3ccccc3o2)cs1 +O=C(CC1CCCCC1)NCC(=O)Nc1ccc(-c2ncno2)cc1 +O=C1CCC(C(=O)N2CCN(C(=O)CCC3CCCCC3)CC2)N1 +Cc1cccc(CN2CC3CN(C(=O)c4cnccn4)CC3C2=O)n1 +Nc1cccc(C(=O)OCC(=O)NCc2cccs2)c1 +COc1ccc(OC)c(C(=O)c2cc(C)ccn2)c1 +C=CCNC(=O)CCc1c(C)c2ccc(C)cc2oc1=O +Cc1c(C(=O)NCCCNC(=O)C(C)C)nc2cc(Cl)ccn12 +CCOC(=O)CCC(=O)c1ccc(Cl)c(C)c1 +Cc1ccc(C)c(C(=O)NCC(C)(C)c2ccncc2)c1 +CC1=CC(CC#N)C(C(C)C)CC1CC(=O)N1CCOCC1 +CCOC(CC)C(=O)Nc1cccc(NC(=O)c2ccccc2)c1 +CCN(CC1CCOC1)C(=O)CCSc1cc(F)ccc1F +NC(=O)COc1ccc(NC(=O)CCc2ccccc2)cc1 +Cc1noc(C)c1C(C)NC(=O)C1CCCCC1C(=O)N1CCCC1 +Fc1cc(F)cc(NCc2nccn2C(F)F)c1 +O=C1CN(C(=O)CCCOc2ccccc2)c2ccccc2N1 +O=C(Nc1cccc2ncccc12)c1cccc2cn[nH]c12 +Cc1cc2oc(=O)cc(CNC(C)(C)C(N)=O)c2cc1C +Cc1ccnc(NC(=O)c2cc3cc(C)ccc3o2)c1 +O=C(NCCOc1ccc(F)cc1)C1CSc2nccc(=O)n2C1 +Cc1ccc(N(C)C(=O)CCSc2ccccn2)c(C)c1 +O=C(CSc1ccc2c(c1)OCCO2)N1CCOc2ccccc21 +CC1CC(OC(=O)c2ccc(N(C)C)c(F)c2)C(=O)O1 +CC(NC(=O)N1CCOCC1C)c1noc(Cc2ccccc2)n1 +CCOc1ccc(CC(=O)Nc2cc(C)ns2)cc1 +O=C(NCC(F)(F)F)c1ccc(C#CCCO)cc1 +O=C(OC1CCc2ccccc2C1)c1csc(-c2ncccn2)n1 +CCCCCCOc1ccc(C(=O)NC)cc1N +C#Cc1cccc(N(CC(=O)NC)C(=O)c2cc(C)no2)c1 +COc1ccccc1CNS(=O)(=O)c1ccc2c(c1)CC(=O)N2C +CN(C)c1cc(N2CCCC(NC(=O)c3ccccn3)C2)ncn1 +CC(=O)NC(C)(C)c1noc(C=Cc2ccc(C)cc2)n1 +CC(C)C1(C)Nc2ccccc2N(CCCC#N)C1=O +C=C(C)Cn1nnc(C#N)c1COc1cccc(OC)c1 +CCOC(=O)C1(N)CC1c1c(F)cccc1Cl +O=S(=O)(NCc1cn[nH]c1)c1ccc(F)c(F)c1 +CCOC(=O)C1CCCCN1S(=O)(=O)N(C)C(C)C +CC1CN(c2ncc(F)cn2)CCN1C(=O)OC(C)(C)C +COC(=O)CCCNC(=O)c1nc(SC)ncc1Br +O=C(c1cccc2ccnn12)N(CC#Cc1ccccc1)C1CC1 +CCOc1ccc(Nc2ncnc3c2cnn3C)cc1 +CC(c1cccs1)N(C)C(=O)Cc1ccc(N2CCCC2=O)cc1 +COc1ccc(C(C)NC(=O)c2cn3nc(OC)ccc3n2)cc1 +CN(C(=O)c1ccc(N2CCOCC2)nc1)c1ccccc1 +Cc1cc(CSc2nnc3n2CCCCC3)no1 +Cc1cccn(Cc2ccc(C#N)cc2Br)c1=O +COc1ccc2c(c1)NC1(CCCCC1)C(=O)N2CCCO +Cc1cc(C)n2cc(CNc3cccc(C(F)(F)F)c3)nc2n1 +COc1cccc(Cn2ncc3ccc(C(=O)N4CCCCC4)cc32)c1 +CC(C)(CNC(=O)c1cncc(Br)c1)N1CCOCC1 +Cc1nc(C)c(C(=O)Nc2ccc(C)c(S(C)(=O)=O)c2)s1 +O=C(N1CCN(CCO)CC1)C12CC3CC(CC(C3)C1)C2 +CNS(=O)(=O)c1cc(NC(=O)NCC(C)C)ccc1C +CCCCS(=O)(=O)N(Cc1cccc(C)c1)C1CC1 +CC(Nc1ccc(C#N)cn1)C(O)c1ccc(F)cc1 +Cc1ccc(-c2nnn(C)n2)cc1NC(=O)NC(C)Cn1cncn1 +COc1cccc(OCC(=O)NCc2nc(-c3ccccc3)no2)c1 +C=CCNS(=O)(=O)c1ccc(C(C)(C)C)cc1 +Cc1ccc(C(=O)OCc2nc(-c3cccs3)no2)s1 +CC1=C(C(=O)OCC(C)C)C(c2ccccn2)NC(=O)N1 +Cc1cc(C2CCCN(C(=O)c3ccnc(N(C)C)c3)C2)n[nH]1 +Fc1ccc(CN2CCOC3C(OCc4ccncc4)CCC32)cc1 +O=C(COc1ccc2c(c1)CCC2)Nc1ccccn1 +Cc1ccc(C)c(NC(=O)CSc2ncnc3nc[nH]c23)c1 +CC(=O)N1CCN(C(=O)c2c(C(F)(F)F)nn(C(C)C)c2C)CC1 +COCCCNc1nc(-c2cccnc2)nc2ccccc12 +Cc1nc2ccccc2nc1NCc1ccccc1CN1CCOCC1 +CC(C)(C)c1ccc(C(=O)NCc2ccnc(-n3ccnc3)c2)cc1 +CCc1cc(=O)[nH]c(SCC(=O)Nc2ccc(F)cc2)n1 +CCn1cc(S(=O)(=O)N(c2ccc(C)cc2)C(C)C)cn1 +CCC(CCO)NC(=O)c1c[nH]c2cc(OC)ccc2c1=O +O=C(CSc1ccc2c(c1)OCCO2)OCC(F)(F)F +CC(C)(C)CC(=O)N1CCN(Cc2cnc3ccccn23)CC1 +COc1ccc(C(=O)NCc2ccc(NC(=O)C(C)C)cc2)nn1 +O=C(CC1OCCc2sccc21)N(Cc1ccsc1)C1CC1 +CCCn1ncc(CN2CCN(Cc3ccc(Cl)cc3)CC2)c1C +CN(CCC#N)S(=O)(=O)NC1CCc2cc(F)ccc21 +CCc1ccccc1N1CC(C(=O)Nc2ccnn2C(C)C)CC1=O +CCCCN(CC)C(=O)c1cc(S(N)(=O)=O)c(C)o1 +CCc1nc(CC(=O)OCC(=O)N2CCCCCC2)cs1 +COc1cccc(S(=O)(=O)NCCC(O)C2CC2)c1 +O=C(Nc1ccccc1-n1cnnn1)c1ccn(-c2ccccc2F)n1 +CCCNc1ccc(C(=O)N2CCCN(c3ncccn3)CC2)cn1 +CC(C)c1cnc(CN2CCN(C(=O)CC3CCCCC3)CC2)o1 +N#Cc1ccc(C(F)(F)F)nc1N(CCC(N)=O)Cc1ccccc1 +COc1ccccc1-c1c(C)sc2nc(C)c(N)n12 +CC(C)COc1nc(NCC(=O)N(C)C)ccc1N +O=C(Nc1ccc(C(=O)N2CCCCC2)c(Cl)c1)c1ccccn1 +CCC(=O)c1ccc2c(c1)N(COC)C(=O)C(C)O2 +N#CCc1c(-c2ccccn2)nc2c(F)cccn12 +Cn1c(Oc2cccc(Cl)c2)cc(=O)n(C)c1=O +CC(CNC(=O)Cn1cnc2c(cnn2C)c1=O)Oc1ccccc1 +CCCc1nnsc1C(=O)NCC#Cc1ccccc1F +Cc1sc2nnn(CC(=O)c3ccc(Cl)cc3)c(=O)c2c1C +CCC(C)Nc1nc(-c2cc(C)oc2C2CC2)cs1 +Cc1ccccc1C(=O)NCCC(=O)NCc1ccc(Cl)cc1 +Cc1ccc(CN(Cc2ccco2)C(=O)NCc2cccnc2)s1 +O=C(C1CCCN1C(=O)c1ccco1)N1CCc2cc(F)ccc2C1 +Nc1ccc(S(=O)(=O)Nc2cn[nH]c2)c(Cl)c1 +CC(C)C(C#N)N(C)S(=O)(=O)c1ccc2c(c1)OCCO2 +C#CCNC(=O)CNC(=O)NCCc1cc(Cl)cc(Cl)c1 +COc1ccc2nc(C(C)N(C)Cc3ccccc3)[nH]c2c1 +CN(C)C(=O)C1CCN(c2ncnc3sc4c(c23)CCCC4)CC1 +Cc1ccc(OCCOCCn2cnc3ccccc3c2=O)cc1C +O=C(NCCO)c1ccccc1CCc1ccccc1 +CCc1cccc(C)c1NC(=O)CS(=O)(=O)c1ccccc1F +CCCOCC(=O)N1CCC(Oc2cccc(Cl)c2)C1 +CCOc1ccc2nc(C(=O)N3CCC4(CC3)OCCO4)cn2n1 +CCn1ncc(CN2CCN(Cc3cc(C)cc(C)c3)C(=O)C2)c1C +COc1ccc(-c2noc(C(=O)Nc3ccncc3)c2N)cc1 +Nc1nc2cccc(Oc3cccc4cccnc34)n2n1 +Fc1ccc(CNc2cnn(-c3ncccn3)c2)cc1C(F)(F)F +Cc1ccc(CN2CCN(C(=O)c3csnc3C)CC2)cc1 +COc1cc(C(=O)Nc2nonc2C)cc(OC)c1C +CCc1onc(C)c1NC(=O)CCOCc1ccccc1 +O=C(Nc1cc(F)ccc1O)c1cc(N2CCCC2=O)ccc1Cl +Cc1cc(C(=O)Nc2cccc(S(=O)(=O)N3CCCC3)c2)c(C)o1 +CCN(C(=O)c1ccc2c(c1)COC2)c1ccc(Br)cn1 +CCN1CCN(C(=O)C2CNc3ccccc3O2)CC1 +COc1cccc(C(=O)Nc2cc3[nH]c(=O)oc3cc2C)c1 +Cc1noc(COC(=O)c2ccccc2OCc2cscn2)n1 +COC(=O)CCC(=O)NC(c1ccccc1)C(C)C +N#Cc1cc2c(nc1N1CCC(CN3CCCCC3=O)CC1)CCC2 +CCOC(=O)CCCN1CCOC(c2ccc(F)c(Cl)c2)C1 +CCOCc1ccccc1NS(=O)(=O)c1ccc(OC)cc1 +CC(=O)NCCNC(=O)c1ccc(CNc2ccc(C)cc2)cc1 +CCOc1ncccc1NC(=O)N1CCC(CN2CCOCC2)CC1 +CC(C)OCCCNC(=O)c1noc2c1CCc1sccc1-2 +Cn1cc2c(c1-c1ccc(Br)cc1)c(=O)n(C)c(=O)n2C +Nc1ncc(-c2ccncn2)c(-c2ccc(C(F)(F)F)cc2)n1 +CCOc1cc(NC(=O)c2ccc[nH]2)ccc1OC +CCCN(CC1CC1)C(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +Cc1ncsc1C(=O)OC1CCN(CC(F)F)CC1 +CCNC(=O)C(N)c1ccc(OC)c(OC)c1OC +CC(c1ccccc1)N1CC(C(=O)NCC(=O)N2CCCC2)CC1=O +Cc1cccc(NC(=O)Nc2ccc(C)cc2OCC(=O)N(C)C)c1 +Cc1ccc(CNC(=O)c2ccc(C#N)cc2)n1C +CC(=O)Nc1nc(C(=O)NC(C)c2cc3ccccc3o2)cs1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCC1CCC1 +COc1ccc(CN2CC(C(=O)Nc3ccc(C)cc3)CC2=O)cc1 +N#Cc1ccccc1NC(=O)CNc1ccccc1N1CCCC1=O +Cc1ccc2nc(SCC(=O)Nc3nccs3)n(C)c(=O)c2c1 +COC(=O)c1ccc(C)c(NC(=O)c2cccc(-n3cnnn3)c2)c1 +CNc1nc(-c2cc(-c3ccccc3)nn(C)c2=O)cs1 +COc1c(F)cc(NC(=O)C(C)c2ccsc2)cc1F +O=C(Nc1cc[nH]n1)c1cc2c(s1)-c1ccccc1CC2 +CCC(C)C(=O)Cn1cnc2scc(-c3ccc(F)cc3)c2c1=O +COc1cccc(NCCC(O)c2ccc(F)c(F)c2)c1 +COCCn1ccc(NC(=O)C2CC3CCC2O3)n1 +CC(NC(=O)CN(C)c1ccc(F)cc1)C(=O)N1CCCCC1 +CCCn1c(=O)cc(N2CCCC(C(=O)OCC)C2)[nH]c1=O +COc1cccc2c1OCC(NCc1cccn1-c1cccnc1)C2 +COc1ccc(F)cc1NC(=O)N1CCC(OC(C)=O)CC1 +CC(CNC(=O)C(C)NC(=O)c1ccoc1)Oc1ccccc1 +Cc1cc(-c2nn3c(COc4ccc(Cl)cc4)nnc3s2)no1 +CCOc1ncccc1CNC(=O)c1sc(C)nc1C +CCc1nc2n(n1)CCCC2NC(=O)c1cc(C)ccc1C +C=CCNC(=O)C1CC(=O)N(c2ccc(F)c(Cl)c2)C1 +O=C(Nc1ccc(F)cc1)C1CCN(C(=O)c2ccccc2)CC1 +O=C(NC1C2Cc3ccccc3C21)c1ccc(OCC(F)F)nc1 +CCN(Cc1cc(C(N)=O)cs1)Cc1c(F)cccc1F +CNC(=O)CCC(=O)N1CC(C)Oc2ccccc21 +Cn1ncc2c1CCCC2NC(=O)C1CC=CCC1 +Cc1csc2nc(Cc3cc(F)cc(F)c3)[nH]c(=O)c12 +Cc1ccc2c(c1)C(NC(=O)c1ccncc1)CNC2 +COC(=O)c1ncccc1OCc1csc(-c2cccs2)n1 +O=c1[nH]c2ccccc2cc1CNc1cccc(-c2nc[nH]n2)c1 +Cc1cc(SCC(=O)NCc2ccccc2)ncn1 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)Nc1cccc(C#N)c1 +Cc1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)nc1 +O=C(Cn1ccnc1)c1ccc2c(c1)OCCCO2 +COCc1cc(CN(C)C(=O)c2ccc3nc(C)c(C)nc3c2)n[nH]1 +CS(=O)(=O)c1ccccc1C(=O)NCCCC1CCCC1 +Cc1ccc(C)c(S(=O)(=O)CC(=O)Nc2cccc(F)c2)c1 +CCCNC(=O)N1CCN(Cc2cscn2)CC1 +O=C(c1ccnc(N2CCCC2)n1)N1CCCC(n2cncn2)C1 +Cc1nc(C)c(C(C)NC(=O)c2cc3ccccc3c(=O)[nH]2)s1 +Cn1ncc2c1C(COCC1CC1)CN(C(=O)c1ccsc1)C2 +COc1ccc2oc(C)c(C(=O)Oc3cccc(C(N)=O)c3)c2c1 +CCN(CC)C(=O)N1CCC(C(=O)N(C)Cc2cnn(C)c2)CC1 +COc1ccc(-c2cc(C(=O)NCC(C)C)no2)cc1OC +CCCCN(C)C(=O)Nc1cc(F)c(OC)c(F)c1 +COC(=O)CNc1nc2cc(Br)ccc2[nH]1 +COc1ccc(-n2cc(CNC(=O)Cn3ccccc3=O)nn2)cc1 +COc1ccc(NC(=O)NC(CO)c2ccccc2)c(OC)c1 +C#CCN1CCN(CC(=O)NCc2cccc(OC)c2)CC1 +O=C(Nc1nc(-c2ccc3c(c2)OCCO3)cs1)c1cccnc1 +COc1cc(Cl)ccc1C(=O)NCc1cccc(C)n1 +COCC1(C(=O)N2CCN(CC3CCCO3)CC2)CCC1 +Cc1nc(-n2cccc2)sc1C(=O)N=c1[nH]c2ccccc2[nH]1 +c1ccc(-n2ncc3c(NCc4ccc5c(c4)OCO5)ncnc32)cc1 +Cc1cc(C(N)c2nc3c(s2)CCC3)c(C)s1 +Cn1cc(CNC(=O)Nc2ccc(OCC(F)(F)F)cc2)cn1 +COc1ccc(NC(=O)c2ccncc2Cl)cc1CO +CCOC(=O)c1sc(=NC(=O)c2ccno2)n(C)c1C +Cc1nc(C(C)C)c(C(=O)Nc2cccc3[nH]ccc23)s1 +Cc1ccc2oc(C(=O)N3CCC(C(N)=O)C3)cc2c1 +CN(Cc1ccc(O)cc1)S(=O)(=O)c1cccnc1 +CC1=C(C(=O)Nc2ccccc2)C(c2cccc(F)c2)NC(=O)N1 +O=C(Cn1ncc(=O)c2ccccc21)OCc1ccccn1 +Cc1cc2ccccc2c(=O)n1CC(=O)Nc1ccc2c(c1)OCO2 +COc1cc(OC)c(NC(=O)C2CCCO2)cc1F +C#CCN(C(=O)NCC1CN2CCCCC2CO1)C1CCCC1 +COc1ncnc2c1CN(Cc1nc(-c3cccs3)no1)CC2 +Cc1occc1CN(C)C(=O)Nc1nnc(C(C)(C)C)s1 +Cc1nc(C)c(Cn2cnc3ccccc3c2=O)s1 +CC1Oc2ccc(NC(=O)C3Cc4ccccc4S3)cc2NC1=O +Cc1cccc(C)c1NC(=O)C(C)Nc1ccc2c(c1)oc(=O)n2C +CCCNC(=O)N(C)CCOc1ccccc1OC +COc1ccc(-c2ccc(Cl)cc2)n2nc(N)nc12 +Cc1ccc(CN2C=NS(=O)(=O)c3ccccc32)cc1 +COc1ccc2c(CC(=O)N3CCC(C)CC3)coc2c1 +Cc1cc(Br)ccc1NC(=O)CNC(=O)COC(C)C +CC(C)Sc1ccc(CC(=O)NCCn2ncccc2=O)cc1 +NC(=O)CCOc1ccc(NC(=O)C2CC=CC2)cc1 +CC(CCc1ccc(F)c(F)c1)NC(=O)CN1CCCOC1=O +NC(=O)c1ccc(CSc2nnc(C3CCCCC3)o2)cc1 +Cn1ccc(C(=O)N2CCC(OCc3ccccc3F)CC2)cc1=O +CCC(C(=O)Nc1ccccc1OC)n1c(C)cc(C)nc1=O +CC(NC(=O)C1CCCN(C(=O)c2ccccc2)C1)C1CCCCC1 +CS(=O)(=O)c1cc(C(=O)OC2CCOC2)c(Cl)cc1Cl +CN(Cc1nccs1)C(=O)c1c[nH]nc1-c1ccccc1Cl +COC(=O)C1Cc2ccccc2N1C(=O)C1CC1c1ccco1 +COCCCN(C)C(=O)NC1CCCN(Cc2ccccc2)C1=O +COc1ccccc1C(C#N)NC(=O)CCSc1ccccn1 +CC(NS(N)(=O)=O)c1ccc2c(c1)CCCC2 +N#Cc1nnn(-c2cccc(C(F)(F)F)c2)c1C1CCC1 +CC(=O)c1c(C)n(CC(=O)NC2CCCC2)c2ccccc12 +Cc1ccc(CNC(=O)c2cc(C)nn2C)c(OCC2CCCO2)c1 +CC#CC(=O)NC1CCCc2nc(-c3ccccc3)ncc21 +Cc1onc(-c2ccccc2)c1C(=O)NCc1cnn(C)c1C +NC(=O)CC1CCCCN1C(=O)Cc1cccc(F)c1 +COc1ccc(C(=O)C2CCCN2C(C)=O)c(OC)c1 +Cn1cc(C(=O)NCCN2CCCS2(=O)=O)c(C(C)(C)C)n1 +COCc1ccccc1NCC(=O)NCC(F)(F)F +O=C(CCNC(=O)NC1(c2ccccc2F)CC1)NC1CCCCC1 +COc1ccc(OCC(=O)N2CCNC(=O)C2)cc1 +Cc1cc(CNC(=O)CCn2ncc(=O)c3ccccc32)ccc1F +O=C(NCC1CCCO1)c1cc(-c2ccco2)nn1-c1ccccc1 +CS(=O)(=O)N1CCCC(C(=O)NCC(F)(F)F)C1 +CCOCC1CN(Cc2ccc(F)cc2)Cc2cn(C)nc21 +COc1ccc(F)cc1S(=O)(=O)Nc1ccccn1 +O=C(NC1CCCc2c1cnn2Cc1ccccc1)c1ccncc1 +Cn1nccc1CNC(=O)NC(CC(C)(C)C)c1ccc(F)cc1 +Cc1nn(C)c(C)c1C(=O)N1CCN(Cc2ccncc2)CC1 +O=c1[nH]c2cc(Cl)c(C(O)c3cccc(Cl)c3)cc2[nH]1 +C#CCNC(=O)CSc1n[nH]c(=O)n1CC1CCCO1 +CCOC(=O)c1cnn(C)c1NC(=O)CSc1ccc(O)cc1 +CC(=O)Nc1ccc(C#CCNC(=O)Cc2ccc(F)cc2)cc1 +COc1cc(Cl)ccc1C(=O)NCc1noc(-c2ccco2)n1 +Cc1ccc(OCC(=O)Nc2nnc(Cc3ccccc3)o2)cc1 +CCOC(=O)CSc1nc2sc(C)c(C)c2c(=O)n1CC +CN(Cc1ccncn1)C(=O)c1coc(COc2cccc(F)c2)n1 +Nc1ccc(-c2n[nH]c(Cc3ccc(N)cc3F)n2)cc1 +Cc1nc(CN2CCCN(c3ccc(C#N)cc3)CC2)no1 +Cc1ccc(-c2ccc(SCC(=O)NCC3CCCO3)nn2)cc1 +Cn1cnc(CNC(=O)N(Cc2cc(F)ccc2F)C2CCCC2)n1 +Cc1cc(C)c(NC(=O)Cn2nc3n(c2=O)CCCC3)c(Cl)c1 +Cc1c(C(=O)Nc2cccc(C(C)O)c2)nnn1-c1ccccc1 +Nc1ccc2c(c1)N(C(=O)c1ccncc1)CCO2 +Cn1nccc1CNC(=O)c1ccc(-c2ccco2)[nH]c1=O +CC(C)COC(=O)N1CCCN(C(=O)c2cscn2)CC1 +COCC(C)N1CC(C(=O)Nc2cc(C)cc(C)c2)CC1=O +COc1ccccc1-c1nnc(C2CCN(Cc3ccccc3)C2)o1 +COCC(=O)N1CCN(c2nc(C)cc(N3CCCCC3)n2)CC1 +Cc1cc(NCCSc2ccccn2)n2nccc2n1 +C#CCN1CCCN(C(=O)c2ccc(Cl)cc2)CC1 +CCOc1ccc(CNc2cccc(N3CCCC3=O)c2)cc1 +O=C(NC1CNc2ccccc2C1)c1cccc(O)c1 +CCOC(=O)C(C)(C)n1nc(C#N)cc1-c1ccco1 +COC(=O)c1ccc(C(=O)OCCn2c(=O)oc3ccccc32)cc1 +CCCC(=O)N1CCOc2ccc(S(=O)(=O)NCC)cc21 +O=C(CNC(=O)c1ccc(Br)cc1)NC1CCCC1O +Nc1cccc(Cn2ccnc2Cc2ccc(F)c(F)c2)c1 +N#Cc1cccc(CNC(=O)CCC(=O)c2ccc(F)c(F)c2)c1 +COCc1cc(C(=O)N(C)c2ccccn2)ccc1F +O=C(COc1ccccc1C(F)(F)F)NCc1cscn1 +Cc1oc(C(=O)Nc2ccc3ncccc3c2)cc1S(N)(=O)=O +CCn1nc(C)c2nc(C(C)C)nc(NCCCOC)c21 +Cc1ncsc1C(=O)N(C)C1CCc2ccccc2C1 +O=C1OC(C(=O)N(Cc2cccs2)C2CC2)Cc2ccccc21 +O=C(COc1ncnc2sccc12)Nc1cc(Cl)ccc1F +O=C(CN1CCOc2ccc(F)cc21)NC1CCCCNC1=O +CC(C)OC(=O)c1cc(N2CCCC2=O)ccc1Cl +O=C(NCCc1cccs1)C1CN(S(=O)(=O)C2CC2)C1 +CCN1C(=O)C(Cc2ccccc2Cl)Oc2cc(N)ccc21 +O=C(Cc1ccccc1Cl)NC1CCN(c2ccc(F)cc2)C1=O +COCCNC(=O)CN1C(=O)C(C)(C)Nc2cc(C)c(C)cc21 +COc1ccccc1NC(=O)NCC(C)(C)N1CCOCC1 +O=S1(=O)CCCN1c1ccc(C#CCCO)cc1F +O=C(c1cnn(-c2ccccc2)c1)N1CCOC(c2ccccc2)C1 +CC(C)(C)NC(=O)C(OC(=O)c1cccs1)c1ccc(C#N)cc1 +Cc1cnc2c(c1)N(C(=O)c1ccc(=O)n(C)c1)CCO2 +Cc1nnc(CNC(=O)Cc2csc(Nc3ncccn3)n2)o1 +Cc1ccc(NC(=O)C(C)OC(=O)Cc2c(C)nn(C)c2C)cc1 +O=C(CCc1ccco1)NCc1ccc2c(c1)OCO2 +Cc1nc(C2CCCN(C(=O)c3ccc4c(c3)OCCO4)C2)no1 +O=c1[nH]nc(CSc2nnc(C3CC3)n2Cc2ccccc2)[nH]1 +CC(OCC1CCN(C(=O)OC(C)(C)C)C1)c1nccs1 +Cc1cccc(C(=O)NC(C)c2nc3ccccc3[nH]2)c1C +CC(Cn1cccn1)Nc1ncc(Br)cc1N +CCCn1nnc(S(=O)(=O)c2ccc(C)cc2)c1N +COc1nccnc1-c1ccc(C)c2ncccc12 +CCOC(=O)c1cc(-c2ccc(F)c(F)c2)nn1C +CC(C)c1nnc(NC(=O)COc2ccc3c(c2)OCO3)s1 +CCOc1cc2c(cc1OCC)CN(C(=O)Nc1cccnc1)CC2 +COc1ccc(C2(CNC(=O)CC(F)(F)F)CCOCC2)cc1 +COc1ccc(C(NC(C)=O)NC(C)=O)cc1OCc1ccccc1 +CCc1nc(CN2CCN(C(=O)c3cc(C)c(C)s3)CC2)cs1 +CCCn1c(NC(=O)COc2ccccc2OC)nc2ccccc21 +CC(C)CC1CN(C(=O)c2ccc(=O)[nH]c2)CCC1(C)O +CN(Cc1nc2ccc(F)cc2[nH]1)C(=O)CSc1ncn[nH]1 +CC(C)c1ccccc1NC(=O)Cn1nc2n(c1=O)CCCCC2 +CC(C)=CCCC1(C)CCC(=O)N(Cc2noc(-c3ccco3)n2)C1 +CCc1nnc(NC(=O)CCc2nc(C(C)(C)C)no2)s1 +CN(C)c1ccc(NC(=O)CSc2nc3ccccc3s2)cn1 +CCCCNC(=O)Nc1cc(NC(=O)C2CC2)ccc1C +CC(C)Cn1ncc(C(=O)NC2CCCC2C)c1C1CC1 +CC(C)N(C(=O)CC1CCOc2ccccc21)C1CCOCC1 +CC(=O)NC(C)(C)c1noc(CC2CCCC(C)C2)n1 +COC(C)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +COCc1cc(C(=O)N(C)CCC(C)C)ccc1F +Cn1cc(NC(=O)c2ccc(F)cc2)c(C(N)=O)n1 +COC(=O)CCCn1nc(NC(=O)c2ccc(F)cc2)cc1C +O=C(NCC#Cc1cccc(Cl)c1)c1cc(C2CC2)on1 +O=C(Cn1c(=O)[nH]c2ccccc21)OCC1CC(=O)N(C2CC2)C1 +Nc1ncc(N)c(-c2ccccc2Br)n1 +CCN(C)C(=O)c1cnc(-c2cccc(C)c2)nc1N(CC)CC +CCC(C)Cn1c(C(C)NC(C)=O)nc2ccccc21 +COc1cccc2sc(NC(=O)CN3CC(C)OC(C)C3)nc12 +CCC(C)N(CCOC)C(=O)c1ccc(C)cc1O +O=C(NCc1cc[nH]n1)c1cccc(-n2cc(Br)cn2)c1 +Cc1cc(-c2c(C)sc(C)c2S(=O)(=O)NC2CCCC2)on1 +Cc1ccc2nc(-c3ccccc3)c(NC(=O)Cn3cnnn3)n2c1 +O=S(=O)(Cc1ccc(Cl)cc1)NCCc1ccoc1 +Cc1n[nH]c(C)c1NC(=O)CNC(c1ccccc1Cl)C(C)C +COCC1CCCN(C(=O)Nc2ccc(Cl)cc2)C1 +COc1ccc(CNC(=O)Nc2c(F)cccc2F)cc1F +CCN(CC(C)C#N)C(=O)c1cccc(Cl)c1Cl +CCCC(=O)Nc1c(C)cc2nc(-n3nc(C)cc3C)sc2c1C +CCCc1ccc(C(=O)N(CC2CCCO2)c2ccncc2)cc1 +Cc1csc(=O)n1CCC(=O)NC1CCCCNC1=O +COC(C)COC(=O)c1cn(C)nc1-c1cccs1 +Cc1noc(NC(=O)c2sc(-c3ccsc3)nc2C)n1 +c1ccc(Nc2ccnc(C3COCCN3)n2)cc1 +C#CCOC(=O)C(CC)N1CCOc2cccc(N)c21 +O=C(Nc1ccc(-c2ccco2)cc1)N1CC(CO)C(CO)C1 +Cc1ccc(C)c(S(=O)(=O)N2CCN(CCO)CC2)c1 +CC1COCCN1C(=O)Nc1ccnn1C(C)C +Cc1ccc(NC(=O)C2CCCN(S(C)(=O)=O)C2)cc1Cl +C=CCn1nnc(NC(=O)c2cccc(Cl)c2Cl)n1 +O=C(NCC(=O)N1CCCCC1)c1cccc(OC(F)F)c1 +O=C(Cc1ccc(F)cc1F)N(Cc1ccco1)CC(F)(F)F +O=S(=O)(NCc1ccncc1)c1ccc(C2CCCCC2)cc1 +COc1ccc(OC)c(-n2ncc(C(C)=O)c2C)c1 +CC1CCC(CCC(=O)N2CCC(C(N)=O)c3ccccc32)O1 +O=C(COc1cccc(F)c1)N1CCC2(CC1)OCCCC2O +CNC(=O)c1ccc(CN2CCCc3cc(F)ccc32)cc1 +COc1ccc(N)cc1NC(=O)C(C)OCc1ccccc1 +Cc1cc(NC(=O)NC(C)C2CCOC2)c2ncccc2c1 +Cc1ccc(NC(=O)CCn2c(=O)[nH]c(=O)c3ccccc32)c(C)c1 +Cn1cc(C2CCCN2C(=O)Cc2cn(C)c3ccccc23)cn1 +Cn1c(SCc2cc(=O)n3ccccc3n2)nc2ccccc21 +Cn1cc(S(=O)(=O)Nc2ncn(Cc3ccccc3F)n2)cn1 +Cc1ccc(CC(=O)Nc2cccc(OCC(N)=O)c2)cc1 +Cc1cc2n(CC(C#N)CCC#N)c(=O)c3ccccc3n2n1 +Cc1cnc(NC(=O)c2coc(NC(=O)c3ccco3)n2)s1 +CC(C)c1nn2c(N)c(C#N)nnc2c1-c1ccccc1 +Cc1nc(CCCC(=O)NC2(C#N)CCC2)cs1 +CN1CCC(CNC(=O)Nc2ccc(=O)n(C)c2)c2ccccc21 +Cc1oc(C)c(C(=O)OCC(=O)Nc2sccc2C(N)=O)c1C +COCCOc1ccc(NC(=O)NCc2cnc(C)s2)cc1 +CC(=O)c1sc2nc(CSc3nncn3C)[nH]c(=O)c2c1C +CCc1cccc(C)c1NC(=O)c1ccc(N2CCNC2=O)cc1 +Cc1ccc(C(=O)Cn2cnc3sc(C)cc3c2=O)s1 +CC(C)(C)CNC(=O)N1CCc2ccc(O)cc2C1 +Cc1ccc(C(=O)NC(c2cccc(F)c2)c2nccn2C)c(C)c1 +O=C(Nc1cccc(-c2nc3ccccc3o2)c1)C1CCCO1 +CCOC(CC)C(=O)NCCc1cccc(F)c1 +O=C(NCCc1ccc(Cl)cc1)C1CC(=O)N(c2ccccc2)C1 +Cc1ccc(NC(=O)NCc2ccc(C(=O)N(C)C)cc2)cc1C +O=C(NCCC(=O)N1CCCCC1)NCC1(c2ccccc2F)CC1 +COC(=O)c1ccccc1NC(=O)C1CC(=O)N(C2CCOCC2)C1 +N#Cc1ccccc1Cn1ccnc1CCOc1ccccc1 +CN1C(=O)COc2cc(NS(=O)(=O)NCc3ccccc3)ccc21 +COC(=O)c1ccc2c(c1)CCN2C(=O)c1ccccc1F +CCNC(=O)C(C)NC(=O)c1cccc(Cl)c1 +COCCN(Cc1cccs1)S(=O)(=O)c1ccc(F)cc1 +Cc1ccc(F)c(CN2CCOCCC2=O)c1F +Cc1cnn(CCC(=O)Nn2cnc3ccccc3c2=O)c1 +CCOc1ccc(C2=CCN(C(=O)Cc3ccc(O)cc3)CC2)cc1 +CCC1(CNC(=O)NCCCc2c(C)noc2C)CC1 +Cc1c(CC(=O)N2CCOCC2)c(=O)oc2cc(O)c(Cl)cc12 +CCCn1nc(C(=O)Nc2ccc3c(c2)OCCCO3)ccc1=O +CC1(C)C2CCC1(CS(=O)(=O)Nc1ccc(Cl)cc1)C(=O)C2 +COc1ccc(C(O)C(C)NC(=O)C(C(C)C)N2CCCC2=O)cc1 +Cc1ccc(C)c(S(=O)(=O)NCC#Cc2ccc(C(N)=O)cc2)c1 +Cc1ccc(Cl)cc1N1CC(C(=O)N2CCNC(=O)CC2)CC1=O +CCN(Cc1cccs1)C(=O)c1ccc(=O)n(C)c1 +CN(Cc1ccsc1)C(=O)COC(=O)c1ccc(CO)cc1 +COc1ccc(CC(=O)N2CC3CC2CC3NS(C)(=O)=O)cc1 +COc1ccc(CN2C(=O)C(=O)c3cccc(C(F)(F)F)c32)cc1 +NC(=O)c1c(NC(=O)CCc2cccc(F)c2)sc2c1CCCC2 +CC(c1ccccc1)N1CCN(C(=O)c2ccccc2F)CC1 +O=C(NCC1CCCN(C(=O)c2cscn2)C1)c1ccco1 +CCN(Cc1cccc(NC(=O)N2CCCC(O)C2)c1)C(C)=O +COc1cc(C)c(C(=O)NCC(C)(C)O)cc1OC +Cc1nc(-c2ccc(NC(=O)c3ccnc(NC4CC4)c3)cc2)oc1C +Cn1nccc1NC(=O)c1cnn(-c2ccccc2)c1 +CCCC1CCC(NC(=O)NCCc2cnn(C)c2)CC1 +CC(C)Nc1cccc(CNC(=O)NCCc2cccnc2)c1 +CCOc1ccccc1NC(=O)Cn1nnc(-c2ccc(C)cc2)n1 +CCCCCNC(=O)C(C)S(=O)(=O)c1ccccc1 +CCCn1c(N)c(-c2csc(N(CC)CC)n2)c(=O)n(C)c1=O +Cc1ccc(C(=O)Nc2c(N3CCOCC3)nc(N)[nH]c2=O)cc1 +CCCCCN(C(=O)c1cnc(C2CCCO2)s1)C(C)C +O=C(c1ccco1)N1CCN(c2nc3ccccc3o2)CC1 +C#CCC(OC(=O)c1cc(C)nc2c1cnn2C(C)C)c1ccccn1 +Fc1ccc(OCCSc2nnc3n2CCCCC3)cc1 +Cc1nc(CC(=O)Nc2ccc(C)c(C)c2)cs1 +CCn1ncc2c(C(=O)N3CCCC(C)C3)cc(-c3ccccc3)nc21 +CCc1cc(C(=O)N2CCN(Cc3ccco3)CC2)cs1 +CC(C)(C)OC(=O)N1CCC2(CC1)CC(=O)c1c(O)cccc1O2 +CC(=O)NCCNC(=O)C(C)Sc1ccc(Cl)cc1 +CC1CCCCN1C(=O)c1cccc(-c2ccoc2)c1 +C#CCNC(=O)c1ccccc1NC(=O)C1CC=CC1 +CCS(=O)(=O)N1CCC(c2nc(C(C)(C)OC)no2)CC1 +O=C(CSc1ncnc2ccsc12)N1CCc2ccccc21 +CCN1CCN(Cc2ccc(C(=O)N3CCCCC3)cc2)C(=O)C1=O +CNC(=O)CN1CCN(C(=O)c2cccc(C)c2C)CC1 +O=C(Nc1cnccn1)c1cc(-n2cccn2)ccn1 +COc1cccc(CNC(=O)c2ccc3ccnn3c2)c1 +O=S(=O)(c1ccc(F)cc1)N1CC2(COC2)C1 +O=C(c1ccc2cc[nH]c2c1)N1CCN(c2ccccc2)CC1 +COC(=O)c1ccc(OCC(=O)Nc2cccc(C(C)=O)c2)cc1 +Cc1noc2nc(C)n(CC(=O)NCCc3ccccc3)c(=O)c12 +NC(=O)c1ccc(NC(=O)c2cc(F)ccc2F)cc1 +O=C(CCNC(=O)C1CCCC1)Nc1ccc(F)c(Cl)c1 +COCC1CC2(CCN(C(=O)c3ccnc4ccccc34)CC2)CO1 +CC(=O)c1cccc(NC(=O)C(C)Oc2cccc(C)c2)c1 +CC(C)CCC(=O)NCC(=O)N1CCOCC1CC(C)C +Cc1ccnc2nc(C(=O)NCc3cccc(OCC(C)C)c3)nn12 +O=C(NCCc1cn2ccccc2n1)NCc1cscn1 +O=C(Nc1ncccn1)c1ccc(Cl)cc1Cl +CCn1c(C)cc(-c2nc(-c3ccc(OC)c(OC)c3)no2)c1C +COCCN1CC(C(=O)N2CCC(O)CC2)CC1=O +CCNc1cc2c(nn1)CCN(C(=O)c1ccc3c(c1)OCO3)C2 +CCc1cc(C(=O)NCc2ccnc(OC3CCC3)c2)[nH]n1 +COc1ccc(F)c(NC(=O)NCc2cccc(OC)c2OC)c1 +CCn1cc(NC(=O)C2(C)Sc3ccccc3NC2=O)cn1 +Cc1ccc(C(N)=O)cc1NC(=O)NCc1ccccc1F +CS(=O)(=O)N1CCC(Oc2nc3c(F)cc(F)cc3s2)CC1 +CCCCn1nccc1NC(=O)C(C)c1cccs1 +CCCc1nnc(NC(=O)CNC(=O)OC)s1 +CCOc1ccc(-c2nnn(CC(=O)N3CCCCCC3)n2)cc1 +Cc1n[nH]c(C)c1CCC(=O)N1CCC(Oc2cccc(Cl)c2)C1 +COCCNC(=O)C(C)Oc1ccc(C)c(C)c1 +O=C(C1CCOC1)N1CCCCC1Cn1cccn1 +CC(CC1CCCCC1)C(=O)N1CCCN(C(N)=O)CC1 +CCCCNC(=O)c1cc(C(C)C)nc2onc(C)c12 +Cc1noc(C(C)NC(=O)C2CCCc3ccccc32)n1 +CCc1nnc(-c2ccc(NCc3cnn(-c4ccccc4)n3)cc2)o1 +COC(=O)c1cnc(NC(=O)C2CCCCN2S(C)(=O)=O)s1 +CCNC(=O)N(C)C1CCN(CC(F)(F)F)C1=O +CC1(C)OC(=O)CC1C(=O)Nc1nc2c(s1)CCCCC2 +CC(C)(CNS(=O)(=O)c1cccs1)c1ccncc1 +COc1ncccc1CNC(=O)NCc1cnn(C)c1 +CC(C)n1c(N2CCCCCC2)nc2c1c(=O)n(C)c(=O)n2C +CCn1cc(C(=O)Nc2cc(-n3nnnc3C3CC3)ccc2F)cn1 +CNC(=O)c1ccc(NC(=O)c2ccc3c(c2)OCO3)cc1 +CC(C)S(=O)(=O)NC1=NCN(CCC2=CCCCC2)CN1 +CCC(C)NC(=O)COc1ncnc2ccc(Br)cc12 +CC(Oc1cccc2ccc(=O)[nH]c12)C(=O)Nc1ccc(F)cc1 +CCn1nc(-c2ccc(OC)c(F)c2)cc(C#N)c1=O +Cc1cc(C(=O)CCC(=O)Nc2ccccc2)c(C)s1 +COC(=O)c1ccc(NC(=O)NCCCc2c(C)noc2C)c(F)c1 +O=C(Cn1ccccc1=O)Nc1ccc(-n2cnc3ccccc32)nc1 +NC(=O)c1ccc(OC(=O)Cc2ccccc2Cl)cc1 +O=c1ccc(C(F)(F)F)nn1Cc1csc(-c2ccccn2)n1 +CC(=O)Nc1ccccc1CNc1cnn(-c2ccccc2Cl)c1 +CC(C)(C)C(=O)NCC(=O)NCc1cnn(Cc2ccccc2)c1 +COc1ccc(Br)c(C(=O)NCc2cccc(F)c2)c1 +CC1CCN(C(=O)CNc2cccc(CCC(=O)N(C)C)c2)CC1 +COC(=O)COC(=O)c1c(C)nn(-c2ccccc2)c1C +CC(C)n1cc(S(=O)(=O)N(C)Cc2nc3ccccc3[nH]2)cn1 +CC(C)(C)OC(=O)N1CCNCC1c1cccc(C(F)(F)F)c1 +COCCNC(=O)C1CCCN(c2cc(=O)n(C)c(=O)n2C)C1 +CC1CN(C)c2ccccc2CN1C(=O)C1CCNC(=O)C1 +COC1CCCC1OC(=O)c1csc(-c2cnn(C)c2)n1 +O=C1CCC2C(CCN2S(=O)(=O)C2CC2)N1Cc1ccncc1 +CCCC(C#N)NC(=O)c1cc(Br)c2c(c1)OCCO2 +Cc1nc(-c2c[nH]c(C(=O)NC(C)CN3CCOCC3)c2)cs1 +CCCCC1C(=O)N(C)CCN1Cc1cc(=O)c(OC)co1 +CC(=O)c1ccc2c(c1)N(Cc1c(C)noc1C)C(=O)C(C)(C)O2 +COCn1nc(CO)cc1-c1ccc2c(c1)CCC2 +CCC(CO)NC(=O)NC1CCCc2ccccc21 +CN(Cc1cccc(F)c1)S(=O)(=O)c1ccccc1Cl +CCNC(=O)CN(CC)C(=O)c1csc(CC(C)C)n1 +COC(=O)C12CCCC1CN(Cc1c[nH]nc1-c1cccnc1)C2 +O=C(NCC1CCOC1)Nc1ccc(Cl)cc1F +Cc1ccc2nc(COC(=O)c3ccc(F)cc3F)cc(=O)n2c1 +O=C(NCC1(O)CCCc2ccccc21)Nc1cc(F)cc(F)c1 +NC(=O)C1Cc2ccccc2CN1C(=O)C1CCCC1 +NC(=O)N1CCCC(C(=O)N2CCN(Cc3ccccn3)CC2)C1 +CCOCC(=O)N1CCC(c2nc(-c3cccnn3)no2)CC1 +CC(=O)N1CCCC1C(=O)N1Cc2ccccc2N(C)CC1C +Cc1ccc(C(=O)N2CCC(OCc3ccccc3F)CC2)c(C)c1 +COc1ccc(-c2nn(CCC#N)cc2C(=O)N2CCCCC2)cc1 +COc1cccc(C2C3C(=O)CCCC3=Nc3nc(SC)nn32)c1 +CCCn1cc(C(=O)NC(COC)c2ccnn2C)c(C)n1 +CCCNC(=O)C(CC)N(c1ccc(C)c(C)c1)S(C)(=O)=O +O=C(NCCCc1nc2ccccc2s1)c1csnn1 +Cc1cc(C2CCCN2C(=O)c2cc3c([nH]c2=O)CCC3)on1 +O=C1Nc2ccc(Br)cc2C1Nc1ccc(F)cc1F +CCOC(=O)c1nocc1C(=O)c1ccc(Br)cc1 +COc1ccc(C(=O)N2CCOCC2)cc1NCc1cccc(F)c1 +C=C(C)CN(CC)C(=O)CCc1nnc(C2CCCCC2)o1 +CN1CCN(C(=O)c2ccc(=O)n(Cc3ccccc3)n2)CC1 +Cc1nnc(N2CCCC3(CN(Cc4cccnc4)CCO3)C2)o1 +O=C(NC1CC1)c1ccc(S(=O)(=O)N2CCCC2)s1 +CCCCc1cc(NC(=O)Cc2ccccc2OC)[nH]n1 +Cc1ccc(-n2ccnc2SCc2nnnn2C2CC2)cc1C +COC(=O)c1ccc(-c2nn3c(C(F)(F)F)nnc3s2)cc1 +CC(=O)Nc1cc(NC(C)=O)cc(C(=O)N(C)CCC(F)(F)F)c1 +O=C1CCCc2c1c(C1CC1)nn2-c1ccc(F)cc1F +CC(=O)c1ccc(F)cc1NC(=O)C1CC(=O)N(C)C1 +Cc1ccccc1C(C)NC(=O)c1cc(C)c(C)c(S(N)(=O)=O)c1 +O=C1CCCc2c1cnn2-c1cccc(Br)c1 +Cc1nc(NCCOc2c(C)cccc2Cl)c2cnn(C)c2n1 +CS(=O)(=O)c1ccccc1-n1cc(NC(=O)N2CCCC2)cn1 +COCC1CCCN1C(=O)CC(C)c1cccc(OC)c1 +Cc1c(C(=O)NCC2CCC2)oc2c1C(=O)CCC2 +COc1cccc(NC(=O)c2cc(OC)c(OC)cc2C)c1 +O=C(OC1CCCCNC1=O)c1n[nH]c2ccccc12 +Cc1ccc(-n2nnc(C(=O)Oc3cccc(C(N)=O)c3)c2C)cc1 +C=CCn1c(C)nnc1SCc1ccccc1C#N +CC(=O)Nc1ccc(F)c(C(=O)NCCC(=O)OC(C)C)c1 +COC(=O)CCN(C)C(=O)c1ccc(N(C)C)cc1 +CCCOc1ccc(C(=O)CN2CCC(=O)CC2)cc1 +CCc1ccccc1NCc1cccc(C(=O)NC)c1 +CC(=O)N(C)Cc1ccccc1NCc1noc(C2CC2)n1 +CC(=O)c1cnn(-c2cccc(F)c2)c1C(F)(F)F +CCS(=O)(=O)N1CCC(Oc2ccc(C#N)cc2)CC1 +COC(=O)CCc1nnc(NC(=O)C2CC=CC2)s1 +CC(C)c1cc(CNC(=O)Nc2ccc(-c3csnn3)cc2)on1 +Cc1cccc(NC(=O)C2CC(=O)Nc3cc(F)ccc32)c1 +O=C(CSc1ccncc1)Nc1ccc2c(c1)OCO2 +Cc1ccc(NC(=O)CC(O)(c2ccc(C)o2)C(F)(F)F)c(O)c1 +COc1cccc(-c2ccc(=O)n(CC(=O)NCCC(C)C)n2)c1 +CC1CN(C2CCN(Cc3cc(F)cc(F)c3)CC2)CCO1 +CC(=O)Nc1ccc(C(=O)N(C)CCOc2ccccc2)cc1 +c1ccc(CCCc2nnc(SCC3CCOCO3)o2)cc1 +CCn1cnnc1CNC(=O)N(Cc1ccccc1)CC(F)F +COc1ccc(NC(=O)c2c(-c3ccccc3)noc2C)c(OC)c1 +Cc1cc(C(C)(C)C)cc(C)c1CCNC(=O)Cn1cnc(C#N)n1 +CSc1nn2c(C(F)(F)F)cc(C(F)(F)F)nc2c1C#N +O=C1OCCN1CCN1CCN(c2nccc(C(F)(F)F)n2)CC1 +CCCOc1ccc(NC(=O)CCc2cnn(C)c2)cc1Cl +CCN(CC)C(=O)Cn1cc(CO)c2cc(F)ccc21 +Cc1cc(N2CCN(C(=O)C3(C)CCCO3)CC2)nc(C(C)C)n1 +O=C(CCNC(=O)Nc1cnn(-c2ccccc2)c1)Nc1ccccc1 +CCOC(=O)c1ccc2c(c1)N(C(C)=O)CC(=O)N2 +COCC(C)NC(=O)c1cccc(OCc2cn3ccccc3n2)c1 +CN1CCN(S(=O)(=O)c2cccc(NC(=O)NC3CC3)c2)CC1 +CC(C)(CS(=O)(=O)N1CCNCC1)C(=O)Nc1ccccc1F +CC(=O)c1ccc(C(=O)N(C)CCN(C)C(=O)OC(C)(C)C)cc1 +CCOC(=O)c1cnn(Cc2ccc(Br)cc2)c1 +Cc1ccc(C)c(C(=O)Nc2cccc(C)c2C(N)=O)c1 +Cn1nc(CNC(=O)NCCCc2ccccc2)cc1-c1ccco1 +O=C(Nc1ccc(Cl)c(C(F)(F)F)c1)c1cnccn1 +CN(CC(=O)NCC#CCOc1ccccc1Cl)S(C)(=O)=O +CCc1noc(CC)c1CNC(=O)Nc1nnc(C(F)(F)F)s1 +CC(C)OC(=O)CCCN1C(=O)c2ccccc2N2C(=O)CCC12C +COC(=O)CCNC(=O)c1cccnc1SC(C)C +Cc1ccccc1OC(=O)c1cc2c([nH]c1=O)CCCC2=O +O=C(NC1CC1)C1CCCN1C(=O)c1ccc2ccccc2c1O +O=C(OCCS(=O)(=O)c1ccccn1)c1cccc(Cl)c1 +CC(C)N1CC(C(=O)NC(C)(C)c2cccc(F)c2)CC1=O +CNC(=O)c1cccc(S(=O)(=O)N2CCOCC2)c1 +O=C(NC1(c2ccc(Cl)c(Cl)c2)CC1)c1cnns1 +CCc1ccc(N2CC(C(=O)Nc3ccnc4ccnn34)CC2=O)cc1 +N#Cc1ccc(OC(=O)COCCc2ccccc2)cc1 +O=c1c2cc(Br)ccc2ccn1CCO +Cc1nn(CC(=O)NC2CCOc3ccccc32)c(=O)c(C#N)c1C +CNC(=O)c1ccsc1NC(=O)c1ccc2c(c1)CCCC2 +CCc1ccc(-c2cn(-c3cccc(N)c3)nn2)cc1 +Cn1nc2n(c1=O)CCN(Cc1ccc(C(F)(F)F)cc1)C2 +Cc1ccc(CN(C)C(=O)NCCOCC(F)(F)F)s1 +CCC(C)(NS(=O)(=O)c1cc(F)c(F)cc1F)C(=O)OC +CC(=O)c1ccc(Nc2nc3ccccc3n3nnnc23)cc1 +COc1ccc(CC(=O)Nc2ccccc2C(=O)NC(C)(C)C)cc1 +c1cc(-c2cc(-c3nc4c5c(ncn4n3)CCC5)n[nH]2)ccn1 +O=C(NCc1ccc(OCc2ccccn2)cc1)c1cccs1 +CC1COCC(C(=O)c2ccccc2Br)N1 +CCCSc1nnc(NCC(F)(F)F)s1 +COCC1CCCN1C(=O)c1cc(-c2ccc(OC)cc2)n[nH]1 +CNC(=O)Cn1nc(C#N)cc1-c1cc(C)ccc1OC +Cc1noc(CNc2ccccc2OCCc2ccccc2)n1 +OC(COc1ccccc1Br)CSc1ccccn1 +Cc1cc(CNc2cc(-c3ccccc3)nc3c(C)c(C)nn23)n(C)n1 +CCc1cc(C(=O)N2CCN(c3cnccn3)CC2)sc1C +COC(=O)CCNC(=O)c1ccc(N2CCc3ccccc3C2)cc1 +COc1ccc(OCC(=O)Nc2nc(C)c(C)s2)cc1 +CCOc1ccccc1OCC(=O)Nc1ccccc1Cl +Cc1ccc(CN(C)C(=O)CNC(=O)c2cccs2)o1 +CNc1snc(C)c1C(=O)NCC(F)(F)F +COc1cc(CC(C#N)C(=O)N2CCCCC2)ccc1O +Cc1ccc(NC(=O)N(C)CC2CC2)cc1N1CCCS1(=O)=O +C#CCN1CCN(C(=O)NCc2ccccc2OC(F)(F)F)CC1 +COc1ccc(CNC(=O)N2CCOC(C(F)(F)F)C2)cc1 +Cc1ccc(COc2cccn(CC(C)C#N)c2=O)cc1 +O=C(NCc1ccnc(-n2ccnc2)c1)c1cccc(C(F)(F)F)c1 +CN(C)c1cccc(C(=O)NCc2cccc(C(F)(F)F)c2)c1 +CN(C(=O)c1cccc(C#N)c1)c1cccc2ncccc12 +O=C(Nc1ccc(Br)cc1)Nc1c[nH]c(=O)[nH]c1=O +CNC(=O)CN1CCN(C(=O)c2ccccc2SC(C)C)CC1 +COCC1(C(=O)NCc2cccc(-c3ccccc3)c2)CC1 +CCC(C)(C)C1CCC(NS(=O)(=O)N(C)C(C)C)CC1 +CC(C)CC(NC(=O)CCn1ccccc1=O)c1ccccc1 +O=C(Nc1ccc2c(c1)OCO2)c1ccc(-n2cnnn2)cc1 +CCc1ccc(NC(=O)CS(=O)(=O)c2nc(C)cs2)cc1 +Cn1cc(C(N)=O)cc1C(=O)OCc1ccc(Cl)cc1Cl +Cc1cccc(C(N)=O)c1NCCOc1cccc(C#N)c1 +COCC(=O)NCCCn1nc(-c2ccccc2)ccc1=O +Cc1cc(Br)ccc1NC(=O)c1cscn1 +Cn1c(N)c(C(=O)COc2ccc(Cl)cc2)c(=O)n(C)c1=O +Cc1occc1C(=O)Nc1ccc(-c2cn3ccsc3n2)cc1 +CNC(=O)Cc1noc(CCc2c[nH]c3ccccc23)n1 +COc1cc(C(=O)N(C)CC(O)C2CC2)cc(Cl)c1OC +Cn1cc(C(=O)Nc2cccc3ncccc23)c(C(C)(C)C)n1 +O=C(NCC1Cc2ccccc21)Nc1ccc(Oc2cccnc2)nc1 +CCOc1ccc(CNC(=O)Nc2cccs2)cc1 +Cc1occc1-c1nnc(SCC(=O)N(C)C)n1-c1ccccc1 +CNC(=O)c1sc(N2CCN(c3ccc(F)cc3)CC2)nc1C +CC(NC(=O)CSc1nnnn1-c1ccc(O)cc1)c1ccco1 +Cc1nn(Cc2ccc(F)c(Br)c2)c(N)c1C#N +Cc1c(N)cccc1OCc1cc(C#N)ccc1F +COc1ccccc1CCNC(=O)Cn1cnc2cc(F)c(F)cc21 +CC(=O)N(C)c1ccc(NC(=O)Nc2ccccc2C)cc1 +CCC(=O)Nc1ccc(S(=O)(=O)NC(C)COC)cc1 +COc1ccc(C(O)CCNc2ccc(F)cc2)cc1OC +CCN(C)C(=O)c1cnc(-c2ccccc2)nc1N(C)C +COc1ccc(COC(=O)C(C)N)cc1C(C)(C)C +O=C1CCC2(CCOC2)CN1Cc1ccc2c(c1)CCCO2 +CCOc1ccccc1NC(=O)c1cccc(N(C)S(C)(=O)=O)c1 +Cc1cc(C)n(CCCC(=O)N2CCC3(CC2)CC(=O)N(C)C3)n1 +COCc1cccc(NC(=O)Nc2cnn(Cc3ccccc3)c2)c1 +CNC(=O)C1CCC(NC(=O)c2cccc(Cl)c2)CC1 +Cc1cc(C2CCC2)nc(NCC(C)(C)N2CCOCC2)n1 +O=C(NCc1ccc(-n2cccn2)cc1)N1CCCC1 +CC(=O)C1(c2ccccc2)CCN(C(=O)CCc2ccccn2)CC1 +Cc1cc(C(=O)N2CCC(Oc3ccc(C)c(C)c3)CC2)[nH]n1 +N#CCc1ccc(NC(=O)C2CC3CCC2O3)cc1 +O=C(NCc1ccccn1)C1CN(c2nc3ccccc3s2)C1 +CCC(c1ccncc1)N(CC)C(=O)c1ccc(-n2ccnn2)cc1 +CCn1nc(C(=O)NCC2CCCO2)c(=O)c2cc(F)ccc21 +O=C(Cc1ccccc1OC(F)F)Nc1ccc2c(c1)COC2 +CS(=O)(=O)c1ccc(NC(=O)c2cccc(O)c2)cc1 +Cc1cccc(CC(=O)NCc2ccccc2-n2ccnc2C)c1 +CCc1nnc2n1CCN(C(=O)c1cnn(-c3ccccc3)n1)C2 +COc1cc(C)c(C)cc1S(=O)(=O)Nc1cccc(C)n1 +c1ccn2c(Sc3ncnc4ccsc34)nnc2c1 +Cc1nc2c(c(C)c1CNC(=O)c1ccc(F)cc1F)c(=O)[nH]n2C +CS(=O)(=O)c1cccc(NC(=O)c2ccncc2)c1 +CCc1ccc(NC(=O)c2cccc(F)c2)cc1N +CC1CC(C)CN(C(=O)Cn2nnc3ccccc3c2=O)C1 +COc1ccccc1N1CCN(C(=O)c2cnc(C)cn2)CC1 +COc1cccc(C(O)C(=O)NC2(C)Cc3ccccc3C2)c1 +CS(=O)(=O)Nc1ccc(N)cc1Oc1ccccc1 +Cc1ccc2ncc(C(=O)OCCCc3ccncc3)n2c1 +Cc1nn(C)c(C)c1CC(=O)N=c1[nH]nc2n1CCCC2 +CCOCCOC(C)C(=O)Nc1c2c(nn1C)CCC2 +Cn1nc(C(C)(C)C)cc1C(=O)Nc1ccccc1OCCC(N)=O +Cc1ccc(-c2c(C(=O)NCc3ccccn3)nc3ccccn23)cc1 +CC1CC1C(=O)NC1CCCN(c2cccnc2)C1=O +Cc1ccc(Br)cc1NCc1nnc(C2CC2)o1 +C#CCNC(=O)c1ccc(NC(=O)c2cccs2)cc1 +Nc1ccc(Oc2ccc3c(c2)CCC(=O)N3)c(Cl)c1 +COc1ccc(CN2CC(C(=O)N3CCC(C)CC3)CC2=O)cc1 +Cc1ccccc1SCC(=O)OCC(=O)N1CCCCCC1 +Cc1noc(C)c1CCC(=O)N(C)Cc1cnn(C)c1 +Cc1cc(CNC(=O)CN(C)S(C)(=O)=O)no1 +CCC(NC(=O)COc1ccc(C(N)=O)cc1)C(C)C +Cn1cc(C(=O)NCc2ccc(OC(F)(F)F)cc2)cn1 +CCn1cc(C(=O)NCCCS(=O)(=O)c2ccccc2)cn1 +Cc1nc(Cc2ccc(F)cc2)sc1C(=O)NC(C)C1CCCO1 +COc1cc(C#N)ccc1OC(C)C(=O)Nc1cc(C)on1 +CN(Cc1ccco1)Cc1nnc(-c2ccco2)o1 +CNC(=O)c1cc(C)ccc1NC(=O)CCc1ccc(F)cc1 +COc1ccc(-c2nnc3sc(-c4ccncc4)nn23)cc1OC +O=c1c(=Cc2ccncc2)sc2nc(-c3ccncc3)nn12 +N#CC(C#N)c1ccc(C(=O)N2CCCC2CO)cc1 +NC(=O)c1ccccc1NC(=O)C1COc2ccccc2C1 +COc1ncc(-c2nnnn2-c2ccccc2)c(-c2ccccc2)n1 +C=CCOCC12CCCOC1CCN(Cc1scnc1C)C2 +CCc1ccc2nc(NC(=O)C(NC(=O)COC)C(C)C)sc2c1 +C#CCN1CCN(C(=O)NCC(=O)Nc2ccccc2)CC1 +CC1CC1C(=O)NCCC(=O)Nc1ccc(Cl)c(F)c1 +O=C(NCC1COCCO1)N1CCC(c2nc3ccccc3o2)CC1 +Cc1noc(C)c1CCCNC(=O)c1cnc(C2CCCO2)s1 +CN(C)c1ncc2c(n1)CN(CCc1cccs1)C2=O +Cc1ccc(C(C)NC(=O)NCc2sccc2C)o1 +Cc1ccnc(NC(=O)CNC2=NS(=O)(=O)c3ccccc32)c1 +Cc1ccc(C(=O)N(C)CCOc2ccccc2)c(O)c1 +Cc1ccc(F)c(C(=O)Nc2cccc(C#N)c2)c1 +COC(=O)c1[nH]c(C)c(C(=O)C(C)N(C)C(=O)C(C)C)c1C +Cc1cc(=O)c(C(=O)NCc2ccc(-c3ccc(O)cc3)cc2)c[nH]1 +CCC(=O)Nc1ccc(O)c(C(=O)N2CCCC(C)C2)c1 +COc1ccc(NC(=O)c2cc3ccccc3[nH]c2=O)c(OC)c1 +Cc1cccc(S(=O)(=O)N2CC3OCCN(C(C)C)C3C2)c1 +Cc1cc(C(=O)Nc2c(C)cccc2C)ccc1F +CCC1C(=O)NCCN1C(=O)Nc1ccc(F)cc1C#N +COC(=O)C1CCCN1C(=O)c1c(C)nc2ccc(C)cn12 +CC(C)n1c(SCc2n[nH]c(=O)[nH]2)nnc1N(C)C +Cc1ccccc1-c1nc(C(=O)Nc2nccn(C)c2=O)cs1 +Cc1ccncc1NC(=O)NC(Cc1ccccc1)C(=O)N(C)C +CCn1nnnc1SC(C)C(=O)Nc1ccc(OC)c(Cl)c1 +C=CCn1c(C)nnc1SCc1ncc(C)c(OC)c1C +COc1ccc(C(C)(C)C)cc1S(=O)(=O)N(C)CCO +COc1ccc(N2C(=O)CC2c2ccccc2)cc1 +Cc1ccc(OC(=O)Cn2nc3ccccn3c2=O)cc1C +COc1ccc(OC(C)C(=O)NCc2c(C)cc(C)[nH]c2=O)cc1 +Cc1csc(NC(=O)N(C)Cc2csc(C)n2)n1 +O=C(NCCCc1ccccc1)Nc1cccc(C(=O)NC2CC2)c1 +CCC(=O)Nc1cccc(NC(=O)c2cn(C)nc2-c2cccnc2)c1 +O=S(=O)(Nc1cccc2cn[nH]c12)c1ccc2c(c1)CCC2 +CCNC(=O)c1cccc(NC(=O)NCc2cc(C#N)ccc2F)c1 +Cc1cc(C#N)ccc1COC(=O)c1ncn(-c2ccccc2)n1 +CN(CCNC(=O)c1cnc(-c2cccnc2)nc1)c1ccccc1 +COCCC1(CNC(=O)NCc2cc(C)no2)CCCC1 +CC1(C)CN(C(=O)c2ccccc2COc2ccccc2)CCO1 +CCCCN(CC)C(=O)c1onc(S(C)(=O)=O)c1N +Cc1nc(C(=O)NCc2ccc(S(N)(=O)=O)s2)cs1 +CC(=O)Nc1ccc(F)c(C(=O)N(C)CC(=O)Nc2cc(C)on2)c1 +O=C(Cc1c[nH]c2ccccc12)OCC(=O)c1ccc(F)cc1 +CCNC(=O)Nc1cccc(NC(=O)COC(C)C)c1 +Cc1cc(Cl)ccc1NC(=O)Cn1nnc2ccccc2c1=O +CCOc1ccc2c(c1)CN(C(=O)Cc1noc3ccccc13)CC2 +CC(=O)c1cccc(OC(C)C(=O)NCc2ncn(C)n2)c1 +C#Cc1cccc(NCC(=O)N2CCC3(CC2)OCCO3)c1 +Cc1ccc(NC(=O)c2cc(N)ccn2)cc1Br +CCN(CCC(=O)OC)C(=O)c1coc(-c2ccccc2)n1 +NC(=O)C1(CNC(=O)c2cnc3ccccn3c2=O)CCOCC1 +Cn1ccsc1=NC(=O)c1cccnc1N1CCCC1 +Nc1nc(N2CCN(CC(F)(F)C(F)F)CC2)nc2ccccc12 +COc1ccc(-c2cc(=O)n(CC(=O)NC3CC3)cn2)cc1 +O=C(COc1ccccc1Cl)Nc1ccc(NCCO)nc1 +COc1ccc(F)cc1C(=O)N1CCCC1C(=O)N1CCN(C)CC1 +Nc1ccc(-c2cn3cc(Cl)cc(Cl)c3n2)cc1 +O=C1CCCN1c1cccc(-c2csc(NC3CC3)n2)c1 +c1ccc(OCCSc2nnc(Cn3cncn3)o2)cc1 +Cc1cc(C)nc(SCC(=O)NCc2cccc(N(C)C)c2)n1 +Cc1cc(C(=O)NC(C)c2ccccc2OC(F)F)c(C)o1 +O=C(Cn1cnnn1)Nc1cccc2ccccc12 +O=C(NCCCSc1ccccc1)C1CC(=O)N(C2CCCC2)C1 +COCCC(=O)N1CCCn2cc(-c3cccc(C#N)c3)nc21 +CCCOc1ccccc1NC(=O)c1scnc1C1CC1 +Cc1c(COC(C)C)cccc1NC1CCN(C(=O)N(C)C)CC1 +Cc1cccc(C)c1NC(=O)c1ccc(-n2cccc2)cc1 +CCCCNC(=O)NCc1ccccc1-n1ccnc1 +O=C(NCc1ccccn1)c1nc2ccccn2c1-c1ccc(F)cc1 +CCc1nc(N(C)Cc2cccnc2)sc1CO +Cc1ccc(C(=O)NCCc2ccccc2Cl)cn1 +CCCC1=C(C(=O)OCC)C(c2ccc(OC)cc2)n2ncnc2N1 +O=C(OCCCc1ccccc1)c1ccncc1F +O=C(NCc1cscn1)c1ccc(-n2cccc2)cc1 +Cc1nn2c(CNC(=O)c3ccc(F)cc3)c(C)nc2s1 +COC(=O)CCNC(=O)c1c(C)[nH]c2ccccc12 +CC(NC(=O)Cc1ccccc1F)c1ccncc1 +CCOc1ccc(C(=O)NCC#Cc2ccc(N(C)C)cc2)cc1 +Cc1ccc(C(=O)NCC2CCN(S(C)(=O)=O)C2)cc1Cl +FC(F)n1ccnc1CSc1ncccc1Br +CC(C)C(=O)c1ccc(S(=O)(=O)N2CCN(C)CC2)cc1 +CCNc1ncnc(Nc2cccc(Cl)c2C)c1N +Nc1ccc(Br)cc1C(=O)N1CCCC1 +CC(Oc1ccc(F)cc1)C(=O)NCc1ccncc1 +Nc1ncnc(Nc2cc(C(F)(F)F)ccc2Cl)n1 +COC(=O)C1CC(O)C(NC(=O)OC(C)(C)C)C1 +COc1ccc2c(ccn2CCC(=O)Nc2nc(C)cs2)c1 +Cc1nc(C2(NC(=O)c3cc(C)n(C(C)C)c3C)CCCC2)no1 +Cc1ccc(C(C)C)c(OC(=O)Cn2c(C)c(C)sc2=O)c1 +Cc1cccc(N2CC(C(=O)Nc3nc(C)cs3)CC2=O)c1 +CCn1cnc2c(Nc3ccc(F)cc3)nc(NCCO)nc21 +Cc1cc(C)c(CNC(=O)c2cc(S(N)(=O)=O)c(C)o2)c(C)c1 +COc1ccc(CN(C(=O)c2c[nH]c3cccc(F)c23)C2CC2)cc1 +NC(=O)CN1CCc2nc(NC(=O)C3CCC3)sc2C1 +CCc1nnc2n1CC(NC(=O)c1cccc(-n3cccc3)c1)CC2 +Cc1cc(OCC(N)=O)ccc1NC(=O)C(C)(C)c1cccs1 +O=C(Nc1ccccc1Cl)NC1c2ccccc2CC1O +Nc1ccc(Cl)cc1C(=O)N1CCc2ccccc2C1 +Cc1ncsc1C(=O)NCCS(=O)(=O)c1ccc(Cl)cc1 +COC(=O)c1nnsc1NC(=O)Cc1ccc(F)cc1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)Nc1ccn[nH]1 +COc1ccc(-c2noc(-c3cccc(N4CCOC4=O)c3)n2)cn1 +CC(C)Cc1ccc(S(=O)(=O)NCCn2cc(Cl)cn2)cc1 +COCc1ccc(CNS(=O)(=O)c2ccc(C(N)=O)cc2)cc1 +O=C(c1cc(F)ccc1F)N1CCN(CC=Cc2ccccc2)CC1 +COc1ccccc1NC(=O)COC(=O)c1sc(C)nc1C +Cc1cc(-c2cc(Cl)c(C#N)cn2)c(C)n1C1CC1 +Cc1ccc(S(=O)(=O)Cc2nc(-c3ccsc3)no2)c(C)c1 +CCCNC(=O)c1cccc(C(=O)Nc2cccn(C)c2=O)c1 +N#Cc1ccc(NC(=O)c2ccc(F)cc2Br)cc1 +COc1ccc(C(C)NC(=O)c2ccc(F)cc2Cl)cc1OC +Cn1cccc1-c1nc2ccc(NC(=O)c3ccccc3)cc2[nH]1 +O=C(c1ccc2nncn2c1)N1CCCCC1CCc1ccccc1 +NC(=O)c1ccc(CNS(=O)(=O)c2cn[nH]c2)cc1 +Cc1ccc(C)c(OC2CCN(c3ncnc4[nH]cnc34)CC2)c1 +Cc1ccc(-c2ccnc(NCc3noc(CC(C)C)n3)n2)c(C)n1 +CC(=O)c1c(C)[nH]c(C(=O)NCC2CCCC(C)C2)c1C +CC(C)CNC(=O)COC(=O)c1ccc(F)cc1Cl +CC(=O)c1c(C)[nH]c(C(=O)Nc2ccccc2NS(C)(=O)=O)c1C +CC(=O)NC(C(=O)NCc1ccc(F)cc1)C(C)C +O=C(Nc1ccc(-n2ccnc2)cc1)c1c(F)cccc1Cl +Cc1cnc(C(=O)OCC(=O)c2cccc(Br)c2)cn1 +CN(CCC1=CCCCC1)S(=O)(=O)c1ccc(N)cc1 +Cc1noc(C2CCCN2S(=O)(=O)c2cccnc2)n1 +CC1(C)C(NC(=O)c2cccc(Br)c2)C2CCOC21 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1cccc(C)c1C +CCc1ccsc1C(=O)N1CCN(C(=O)c2ccc(F)cc2)CC1 +CCC(CC)NC(=O)N1CCN(Cc2csc(C)n2)CC1 +Cc1cc(F)ccc1NC(=O)CSc1nn2cnnc2o1 +CC(C)CCNC(=O)c1cnc(N2CCCCCC2)nc1N +COCCOCC(=O)N1CC2(CCCC2)c2c(F)cccc21 +O=C(CSc1nnnn1C1CC1)Nc1ccc(-c2ncc[nH]2)cc1 +CCOc1ccc(CN(C)C(=O)c2c(C)noc2C)cc1OC +Cc1cccc(CC(=O)Nc2c[nH]cc(Br)c2=O)c1 +CCCCc1noc(CNc2ccc(C(N)=O)c(Cl)c2)n1 +C#CC(OC(=O)C1CCC(=O)N(C)C1c1cnn(C)c1)C1CC1 +CC(=O)c1ccc(NC(=O)Cc2ccc(S(C)(=O)=O)cc2)cc1 +Cc1cccc(NC(=O)CN2CCOCC2C2CC2)c1 +CC(C)N(C(=O)Cc1ccc(F)cc1)C1CCOCC1 +O=c1[nH]c(CN2CCc3sccc3C2)nc2ccsc12 +N#Cc1ccnc(Oc2cccc(Br)c2)c1 +CC(C)(C)c1ccc(C(C#N)NS(C)(=O)=O)cc1 +COc1ccc(CN2CCOC3(CCc4ccccc43)C2)cc1O +COc1ccc(NC(=O)NCc2cccs2)cc1-n1nnnc1C +Brc1ccccc1CCc1nc(C2CC2)n[nH]1 +Nc1nccnc1C(=O)NCc1ccnc(Oc2ccccc2)c1 +Cc1c(C(=O)OC(C)C)sc(NC(=O)c2cccs2)c1C#N +Cc1cccc(C(=O)NCCC(=O)OC(C)C(N)=O)c1 +Cc1cc(NC(=O)NCc2nnc3n2CCC3)ccc1OC(C)C +Cc1ccc(-c2cc(=O)n3ccc(O)cc3n2)cc1 +CCNC(=O)COc1ccc(S(=O)(=O)Nc2ccccc2)cc1C +N#Cc1cccnc1N1CCC(=C2C(=O)Nc3ccccc32)CC1 +CCN(CC)C(=O)N1CCCC(c2ncncc2-c2cc(C)no2)C1 +COC(=O)C1CCCCN1S(=O)(=O)c1ccccc1F +CCOC(=O)c1c(C)oc2nc(CSc3ncccn3)nc(N)c12 +O=C(CN1C(=O)CCc2ccccc21)N1CCCC(n2cncn2)C1 +Cc1ccc(-c2ocnc2C(=O)N2CCC(O)C2)cc1 +CCCNC(=O)c1ccccc1NS(=O)(=O)c1ccc(C)cc1 +CC1CCCC(CNC(=O)N2CCC(CO)CC2)C1 +COc1ccc(-c2nnc(NC(=O)c3cc[nH]n3)s2)cc1 +CCc1nc(CC(=O)N(C)Cc2cc(C)c(OC)c(C)c2)cs1 +CC(=O)Nc1cc(C)ccc1NC(=O)c1ccccc1C +CNC(=O)c1ccc(C)c(NS(=O)(=O)c2c(C)cc(C)cc2C)c1 +COc1ccc(Br)c(C(=O)N2CCCC(C)C2)c1 +CCOc1ccccc1OC1CCN(C(=O)NCC(F)(F)F)CC1 +COc1ccc2c(C(=O)Nc3ccc(F)cc3F)cc(=O)oc2c1 +C#CC(CC)(CC)NC(=O)CCS(=O)(=O)c1ccc(C)cc1 +O=C(NCc1csc(-c2ccco2)n1)c1ccc(O)cc1O +CC(=O)Nc1nc(COC(=O)Cc2ccsc2)cs1 +CCC(=O)N(CC)CC(=O)c1c(C)c(C(=O)OC)n(C)c1C +O=c1ccc2cc(Br)ccc2n1CCCO +O=C(CCC(=O)c1ccc(Cl)cc1)Nc1cccc2cccnc12 +CCOC(=O)C1CCCN(C(=O)C(C)(C)CC)C1 +CC(C)(NCC(=O)NC1CC1)c1ccc(F)cc1Cl +Cc1cccc(C(=O)NCC(=O)N(C)C(C)c2ccc(F)c(F)c2)c1 +C=C(C)CN(CC)C(=O)c1ccc2c(c1)CCCN2 +CCOC(=O)N1CCC(O)(c2ccc(F)cc2)CC1 +CS(=O)(=O)c1cccc(NCC2CCCCC2)c1 +COc1ccc(NC(=O)c2ccc(C(C)=O)cc2)cc1 +COc1cccc(-c2nc3c(C)cccn3c2C#N)c1 +CCOC(=O)CN(CC)S(=O)(=O)c1c(F)cc(F)cc1F +O=C(NCCCNC(=O)C1CC1)c1ccc(Br)cc1 +CCc1c(C(=O)N(C)CC(=O)NC2CC2)cnn1-c1ccc(C)cc1 +Cc1nc(C)c(CC(=O)NCC(C)(C)c2ccccc2C)c(=O)[nH]1 +COCc1nc(N2CC3CC=CCC3C2)c2cnn(C)c2n1 +CCN(CC)C(=O)CCC(=O)Nc1ccc2c(c1)CCC2 +Cc1c(NC(=O)N(C)C(C)CO)cnn1CCC(C)C +COc1ccc(C(C)=O)cc1CSc1nnc(-c2ccoc2C)o1 +CCC(=O)N1CCOc2c(O)cc(-c3ccc(C)s3)cc2C1 +COc1ccccc1C(=O)Nc1cc(C)nn1-c1nc(C)cc(C)n1 +CC(NC(=O)NCc1ncn(C)n1)c1ncc(-c2ccccc2)o1 +Cc1csc(CNC(=O)N(C)C(C)c2ccc(C)s2)n1 +C=CCn1nnnc1SCC(=O)Nc1nc2ccccc2s1 +CCCc1c(C(=O)N(C)C)cnn1-c1ccccc1C +CC(C)NC(=O)COC(=O)c1sccc1C(C)C +CC(C)OC(=O)c1ccn(Cc2csc(C3CC3)n2)c(=O)c1 +Cn1c(C(=O)NCc2cccc(Cl)c2)cc2cnc3[nH]ccc3c21 +Fc1ccc(CNc2ccc3nccnc3c2)cc1 +CN(C)c1ccc(C(=O)NCc2ccc(S(C)(=O)=O)cc2)cn1 +Cn1nnnc1SCCOc1cccc(F)c1 +C#CCN(Cc1ccc(F)cc1)C(=O)NCc1ncn(C)n1 +OC1COC2(CCN(Cc3cnc(N4CCOCC4)s3)CC2)C1 +CC1CCCC(CNC(=O)NCC2CCCO2)C1 +CCC(CC)N(C)C(=O)c1csc(COC)n1 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+CC(OC(=O)c1ccc(F)cc1F)C(=O)NC1CC1 +Cc1ccc(CNC(=O)CNC(=O)c2ccccc2C)cc1 +CC(C)(C)n1cc(C(=O)OCC#Cc2ccccc2)cn1 +Cn1c(Cn2ncn3cccc3c2=O)nc2ccccc21 +Nc1ncc2ccc(-c3ccc(OC4CCCCO4)cc3)nc2n1 +COC(=O)c1ccc(OC(C)C)c(NC(=O)Cc2ccc[nH]2)c1 +CNC(=O)c1ccc(NC(=O)Cc2cccc(OC)c2)cc1 +CCOCCCNC(=O)N1CCc2ccc(Cl)cc2C1 +COc1ccc(Cl)cc1NC(=O)CSc1cn[nH]n1 +CC(C)C(Sc1nnc(C(C)(C)C)o1)C(=O)NC(C)(C)C +Cc1ccc(C)c(C(=O)CCC(=O)NCC(C)(C)N2CCOCC2)c1 +Cc1csc(=O)n1CCc1nc(-c2ccncc2)no1 +Cc1cc(C)n(-c2ccc(CNC(=O)NCC(F)(F)F)cn2)n1 +CN(Cc1cccc(F)c1)C(=O)CNC(=O)c1cccc(F)c1 +COc1ccc(OCCNC(=O)c2ccc3ncccc3c2)cc1 +Cn1c(=O)oc2cc(-c3cc(Cl)c(C#N)cn3)ccc21 +Cc1ccc(C(=O)N2CCCC2c2nc3ccccc3n2C)c(=O)[nH]1 +CCn1nc(C(=O)Nc2nc(CC(=O)NC)cs2)cc1C +Cc1ccc(C)c(S(=O)(=O)N(C)Cc2ccc(C#N)cc2)c1 +NC(=O)c1ccc(OCC(=O)Nc2cccc3ccccc23)cc1 +Cc1nc2cc(NC(=O)c3ccccc3N3CCOCC3)ccc2o1 +CC(=O)N1CCC2(CC1)CCN(c1ncccc1C#N)CC2CO +Fc1ccccc1-n1nc(-c2ccncc2)c2c1CCNC2 +COc1cc(C)c(S(=O)(=O)NCc2cn[nH]c2)c(C)c1 +CC(CNC(=O)Nc1nncs1)N(C)c1ccccc1 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+CC(=O)NCC(=O)N1CCC(c2cc(-c3ccc(F)cc3)n[nH]2)CC1 +COc1ccc(C(=O)CNC(=O)c2cnn(-c3ccccc3)c2C)cc1 +COC(=O)c1cc2c(C)[nH]c(C)c2cc(C(=O)OC)c1=O +O=C(c1ccno1)N1CCC2(CC1)CN(CC1CC1)C2=O +COc1ccc2c(Sc3nnnn3C)ncnc2c1 +Cc1ccccc1-n1c(SCCCC#N)nnc1-c1cccnc1 +Cn1nc2n(c1=O)CCN(Cc1ccc(Cl)cc1)C2 +O=C1OCCN1Cc1nc(C2(c3ccc(F)cc3)CCOC2)no1 +O=c1ccc(S(=O)(=O)N2Cc3ccccc3C2)c[nH]1 +Cc1c(C(=O)Nc2ccc(F)cc2)nnn1-c1ccccc1 +O=C(NCc1cccc(F)c1)c1ccc2[nH]cnc2c1 +Cc1cc(NC(=O)c2cnc(N(C)C)nc2N)no1 +CC(NC(=O)C1C2CCCC21)c1cn(-c2ccccc2)nn1 +CCn1cc(CN2CCNC(=O)C2C(C)C)cn1 +Cn1nnnc1-c1cccc(C(=O)NCCn2cnc3ccccc32)c1 +Cc1nc(-c2ccc3c(c2)CCN3C(=O)c2ccccn2)no1 +COC(=O)Cc1ccc(NC(=O)c2cnn(C)c2N)cc1 +COc1cccc(CN(C)C(=O)Nc2ccc3c(c2)OCCO3)c1 +CNC(=O)CCc1cc(C2CCN(c3cnccn3)CC2)nc(C)n1 +CCNC(=O)c1ccc(CNC(=O)c2cc(C)sc2C)cc1 +CC(C)NC(=O)c1cccn2c(-c3ccc(F)cc3)nnc12 +CCCCn1nc(C(=O)Oc2ccc(C#N)cc2)ccc1=O +CC(CO)C(C)NC(=O)Nc1ccc(F)c(C(F)(F)F)c1 +Cc1ccc(C(O)CNC(=O)c2ccc(F)c(F)c2)cc1 +Cc1csc(C(Cc2ccsc2)NC(=O)Cc2nonc2C)n1 +Cc1cnc(CCNC(=O)CC2CC3CCC2C3)s1 +COC(=O)c1cc(NC(=O)c2cc(F)ccc2F)cc(C(=O)OC)c1 +CCOC(=O)c1sc2ncnc(N3CCC(C(N)=O)CC3)c2c1C +Cc1ccccc1C1(CNC(=O)NCc2ccccn2)CCOCC1 +CCCNC(=O)c1cn(Cc2ccco2)c2cccc(N)c2c1=O +Cc1nn(C)c(C)c1CCC(=O)NCc1ccc(S(C)(=O)=O)cc1 +COC(=O)c1sccc1Cn1ccnc1S(C)(=O)=O +CN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)CCc1ccc(F)cc1 +CC(NC(=O)CSc1nncn1-c1ccccc1)c1ccccc1 +COc1ccc(CCC(=O)Nc2cc(N3CCOCC3)ncn2)cc1 +Cc1cc2c(cc1O)C(c1c[nH]c(=O)c(Cl)c1)NCC2 +Cc1cccc(CSc2nnc(-c3ccco3)n2N)c1 +CCc1nnsc1C(=O)Nc1ccc(N2CCOCC2)nc1 +CCN(C(=O)c1ccc(Cl)cn1)C(c1cccnc1)C(C)C +Cc1nn(CC(=O)NCCCN2CCOCC2)c(=O)c2noc(C)c12 +Cc1noc(C)c1C(=O)NC1C(c2ccccc2)CC(O)C1O +CCOc1ccc(-n2nnc(CO)c2C2CCCCC2)cc1 +Cc1cccc(NC(=O)c2cc3c(=O)n4cccc(C)c4nc3n2C)c1 +CC(C(=O)N1CCCC1)N1CCN(c2ccc(Cl)cc2)CC1 +CC(NC(=O)c1ccc(=O)n(C)c1)c1ccc2[nH]ccc2c1 +CCc1cccc(C)c1NC(=O)COc1cc(OC)ccc1C(C)=O +COc1nccc(NC2CC(=O)N(C3Cc4ccccc4C3)C2)c1C#N +CCC(C)n1ncc(C(=O)N2CCc3cc(F)ccc3C2)c1C1CC1 +CC(CO)C(C)NC(=O)Nc1cc(-n2cccc2)ccc1F +CC(NC(=O)Nc1ccccc1)C(=O)NCc1ccco1 +Cc1ccc(C(=O)N(C)Cc2nc(-c3ccccc3)no2)cc1 +CC(C)c1nc2ccc(NC(=O)Cc3ccc[nH]3)cc2s1 +COc1ccc(-c2nnc3n(C)c4ccccc4n23)cc1N +O=C(Cn1nc(-c2cccs2)ccc1=O)Nc1cccnc1 +O=C(Nc1cccc(-n2cnnn2)c1)c1cnc2ccsc2c1 +CCOc1ccc(NC(=O)c2cccn2C)cc1OC +Cc1ccc(-c2nc(C(=O)NCC(C)Cn3cccn3)cs2)cc1 +Cc1nc(CCNc2ncc(Br)cn2)cs1 +CCOc1ccc(CC(=O)Nc2ccc(N3CCCC3=O)cc2)cc1 +COC(=O)c1ccnc(NCc2c(OC)ccc(F)c2F)c1 +COc1ccc(C(=O)CSc2nnc(Cn3cncn3)o2)cc1 +CCCc1cc(C(=O)Nc2nccn(C)c2=O)sc1C +CCC(C)NS(=O)(=O)c1ccc2c(c1)NC(=O)CS2 +COC(=O)c1cn(CCCc2nc3ccc(C)cc3c(=O)[nH]2)nn1 +Cc1noc(C)c1Cn1nnc(CO)c1Cc1ccc(F)cc1 +CCS(=O)(=O)N1CC2CN(c3ccccc3)C(=O)C2C1 +CCOCC1CN(C(=O)Cc2ccc(OC)cc2)Cc2ccnn2C1 +CC(C)Oc1ccccc1C(=O)NCc1cccc(NC(N)=O)c1 +Cc1cccc(C(=O)N2CCC(C(=O)N3CCC(C)CC3)CC2)c1O +CC(=O)c1csc(NC(=O)c2cc3ncc(C(C)=O)c(C)n3n2)n1 +Cc1ccc(S(=O)(=O)NCCC(=O)Nc2cccnc2)c(F)c1 +c1ccc(-c2nn3c(CN4CCOCC4)nnc3c3ccccc23)cc1 +CC(Sc1ncnc2sc3c(c12)CCC3)C(=O)NC1CC1 +CCOC(=O)c1csc(NC(=O)Cn2c(C)c(C)sc2=O)n1 +COC(=O)C1(NC(=O)C2CC=CCC2)CCC(C)CC1 +O=C(COc1ccccc1O)Nc1ccccc1Cl +O=c1[nH]nc(CNc2nccc(OCc3ccccc3)n2)[nH]1 +CCCc1nnc(NC2CC(=O)N(c3ccccc3OC)C2)o1 +CC(=O)NC1CCCN(C(=O)c2c(C)nn3c(C)cc(C)nc23)C1 +COc1ccccc1Cn1ncc2[nH]c(-c3ccco3)nc21 +CC1(C)CN(C(=O)c2ccc3c(c2)CCCC3)CCO1 +CCc1cc2c(=O)n(CC(=O)c3ccc(OC)c(F)c3)cnc2s1 +COc1ccc2cc(C3CN(c4ccc(C)nn4)CCO3)ccc2c1 +O=C(NCC1CC1)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +COc1ccc(NC(=O)c2cc(F)ccc2N)cc1 +COCCC(C)NC(=O)N1CCOC(c2ccc(F)c(C)c2)C1 +O=C(CCC(=O)NCc1cccs1)NCc1cccs1 +NC(=O)Cc1ccc(OCc2ccccc2F)cc1 +COc1cc(C)ccc1OCCC(=O)Nc1cc(C)nn1C +CC(C)(C)c1ccc(Cc2cnc(N)nc2N)cc1 +Cc1ccccc1OCc1nc(-c2cccc(N)c2)cc(=O)[nH]1 +CC1CC(Sc2nnc3c(Cl)cc(Cl)cn23)C(=O)O1 +CCc1ncc(C(=O)NC(CC(C)C)C(N)=O)cn1 +CCc1cc2c(=O)[nH]c(SCCC#N)nc2s1 +CN(Cc1ccncc1)S(=O)(=O)c1ccccc1F +O=C(CC1CCCC1)NCCNC(=O)c1c[nH]c2ncccc12 +NC(=O)C1CCN(C(=O)Cn2nc(-c3ccccc3)ccc2=O)CC1 +O=C(C1CC1)N1CCN(C(c2ccccc2)C(F)(F)F)CC1 +O=C(Cc1ccc[nH]1)Nc1ccccc1C(=O)NC1CC1 +CC(=O)Nc1ccc(C(=O)N(C)C2CCCc3ccccc32)cc1 +Cn1cc(CCc2nc(C3CCCCC3)no2)cn1 +COC(=O)Nc1nc2c(s1)CN(S(=O)(=O)C(C)C)CC2 +Nc1c(Nc2ccc3c(c2)OCCO3)ncnc1-n1ccnc1 +CN(C)C(=O)CCNc1cc(C(F)(F)F)ccc1Cl +O=C(NCC1COCCO1)c1cc(-c2ccco2)nc2ccccc12 +C=CCN(CCc1ccccc1)C(=O)Nc1nccs1 +CNC(=O)Cn1cc(NCc2cccs2)cn1 +CS(=O)(=O)c1ccccc1NC(=O)COC(=O)c1ccsc1 +O=C1C(Nc2ccc3nccnc3n2)CCN1c1ccccc1F +Cc1cc(NC(=O)CN2CCN(c3ccc(F)cc3)C2=O)no1 +Cc1cc(-c2csc(NC(=O)CCCn3ccnc3)n2)ccc1F +NC(=O)NCC1CCCCN1C(=O)CCCOc1ccccc1F +CC(C)C(C)(C#N)NC(=O)C1COc2ccc(F)cc2C1 +O=C(CC1NC(=O)c2ccccc2NC1=O)NCc1ccc(F)cc1 +O=C(c1ccccn1)c1cnn2c(-c3ccncc3)ccnc12 +CC(NC(=O)Nc1ccc(F)c(Cl)c1)c1cccnc1 +O=C(CCc1cccs1)NCCc1nc(-c2ccco2)n[nH]1 +O=C(NC1CC(=O)N(Cc2cccc(F)c2)C1)C1CCCCC1 +COc1cccc(CN2CCN3C(=O)N(C4CCOCC4)CC3C2)n1 +Cc1cccc(C(=O)N2CCCCC2c2ncc[nH]2)c1 +COc1ccc(N(C(=O)c2cnn(C)c2)C(C)C2CC2)cc1 +Cc1ccc(NCc2ccc(C(N)=O)cc2)cc1Cl +CC(C)c1nc2ccc(C(=O)CN3CCC(=O)CC3)cc2[nH]1 +CCn1nc(Cc2cccs2)nc1Cn1c(C)cc(C)nc1=O +Cc1ccc(C(O)CNS(=O)(=O)c2ccccc2C)cc1 +COc1ccc(F)cc1NC(=O)C1Cc2ccccc2C(=O)O1 +Cc1noc(C)c1CCC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +C=CCOC(=O)CCNC(=O)C12CC3CC(CC(C3)C1)C2 +CCOc1ccc2oc(C(=O)Nc3nc(C)cs3)c(C)c2c1 +CN(C)S(=O)(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1 +COC(=O)c1ncn(Cc2sccc2Br)n1 +O=C(NCC1CN(Cc2ccccc2)CCO1)C1CC=CC1 +COC(=O)c1ccc(OCC(=O)c2c[nH]c3ccccc23)c(OC)c1 +Cc1noc(C)c1CC(=O)NC1(C(N)=O)CCCCC1 +O=C1NC2(CCC2)NC1c1ccc(Br)cc1F +O=C(NCCO)NC1CCSc2ccccc21 +Cc1cc(S(=O)(=O)NCC(C)O)c(C)cc1Br +O=C(CSc1nnc(C2CC2)o1)c1c[nH]c2ccccc12 +O=C(NCc1ccco1)c1cccc(-n2cnc3cccnc32)c1 +Cc1nc(-c2ccc(OC(C)C)cc2)ccc1CO +CC(=O)NC(C)C(=O)Nc1ccc(Sc2ccccc2)cc1C +FC(F)(F)c1ccnc(NCc2ccc3c(c2)OCCCO3)n1 +Cc1ccccc1-c1noc(=O)n1CC(=O)Nc1c(C)nn(C)c1C +O=C(Cc1ccn[nH]1)Nc1nc(Cc2ccccc2)cs1 +Cn1cccc1C1CCCCN1C(=O)Cc1ccc(F)cc1F +FC(F)(F)c1cc(Cl)cc2c1OCCCN2 +Cc1c(Cl)ccc2c(=O)c(C(=O)Nc3cccc(O)c3)c[nH]c12 +COc1ccccc1C(=O)Nc1onc2c1CC(C)CC2 +Cc1cc(C(=O)Nc2cc(Cl)ccc2N(C)C)c2c(C)noc2n1 +CC(OC(=O)CCc1ccccc1)C(=O)Nc1ccc(Cl)cn1 +CC=CCCNS(=O)(=O)c1ccc(F)c(NC(C)=O)c1 +Cc1ccc(NC(=O)c2cccc(-c3ccoc3)c2)cc1C(N)=O +Cc1n[nH]c(C)c1N1CCN(CC(=O)Nc2nccs2)CC1 +Cc1coc(-c2cc(NC(=O)Nc3c(C)n[nH]c3C)ccc2C)n1 +CC(=O)c1ccccc1OCC(=O)OCC(C)C +Cn1cc(N2CC3CN(C(=O)c4cccs4)CC3C2=O)cn1 +O=C(c1ccncc1F)N(Cc1ccco1)c1ccc(F)cc1F +CCN(c1cc(C)cc(C)c1)S(=O)(=O)c1c(C)nn(C)c1C +Cc1nnc2nc(-c3ccccc3)nc(-c3ccccc3)n12 +O=C(CCSc1nc2ccccc2s1)NCc1ccccn1 +CCn1cc(Cl)c(C(=O)NC(C)c2nc3ccccc3o2)n1 +CCCC(=O)Nc1cccc(NC(=O)CC(F)(F)F)c1 +COC(=O)c1sc(NC(=O)C2CC2(C)C)nc1C1CC1 +CCC(=O)N1CCCN(C(=O)Nc2ccc3c(c2)CCC(=O)N3)CC1 +CCCOc1cccc(C(=O)N(CC(C)C)C2CC2)c1 +Cc1ccc(CC(=O)NC2CCN(C(=O)c3ccco3)CC2)cn1 +CN(C)c1ncccc1NC(=O)c1cc(=O)[nH]c2ccccc12 +COc1cc(OC)cc(C(=O)NCCCn2ccc3ccccc32)c1 +Cn1ccnc(NC(=O)CCCn2ccc3cc(Cl)ccc32)c1=O +COc1ccc(C(=O)CNc2cccc(Cl)c2)cc1OC +Nc1cccc2c1CS(=O)(=O)N(Cc1ccccc1)C2 +Nc1ccc(Cl)c(NC(=O)CN2CCCc3ccccc32)c1 +Cn1cc(C(=O)N2CC3(CCCC3)c3ccccc32)cn1 +O=C(c1n[nH]c2ccccc12)N1CCC(c2ccc(O)cc2)CC1 +O=C(NCC1OCC(NCc2cccs2)C1O)c1cccs1 +COc1ccc(C)cc1-n1nnnc1SCCC(N)=O +Cc1ccc(NC(=O)NCC2(C)CCCC2)cc1C(N)=O +COCCCNC(=O)c1ccc(C(F)(F)F)cn1 +CC(=O)c1ccc(-c2ccc(C3CC(O)=Nc4c3cnn4C)o2)cc1 +CCc1cccc(OCc2nc(CCCO)cs2)c1 +Cc1nn(CC(=O)N2CCCCC2C)c(=O)c2cc3sccc3n12 +Cc1noc(COCC(=O)N(C)c2ccc(C(C)(C)C)cc2)n1 +Cc1cscc1C(=O)NC1CCN(c2c(F)cccc2F)C1 +Cc1nn(-c2ccc(F)cc2)cc1CNc1ncccn1 +CCCOc1ccc(Cl)cc1NC(=O)CCc1nc(C)no1 +C=CCNC(=O)NCC1COC2(CCC(C)CC2)O1 +C#CC(C)OC(=O)Cc1ccn(-c2ccc(F)cc2)n1 +Cc1c(C)c2ccc(OCC(=O)Nc3nccs3)c(C)c2oc1=O +CC(=O)NC(C(=O)Nc1ccc(CC#N)cc1)C(C)C +COCC(C)OC(=O)c1ccc(N2CCCCC2=O)cc1 +Cc1ccc(S(=O)(=O)CC(=O)NCc2ccccc2)cc1C +Cc1sc(NC(=O)C2CC2c2ccccc2F)c(C(N)=O)c1C +CCn1cnnc1SCc1cn2cc(Cl)ccc2n1 +Cc1ccc(CNC(=O)c2ccc3cc[nH]c3n2)o1 +CC(=O)c1ccc(NC(=O)C(C)Sc2nncs2)cc1 +COc1ccc(C(=O)CCCC(=O)N(C)c2nccs2)cc1 +CCNC(=O)c1ccc(-c2ccc3c(c2)OCCO3)nc1N +CS(=O)(=O)Nc1cccc(C(=O)NC2CCCCCC2)c1 +COc1cccc(NC(=O)CSc2ncccn2)c1 +CCC(Cn1c(=O)oc2ccccc21)NC(=O)C1CCCC1 +COc1cccc(CNc2ncc(-c3ccc(F)cc3)n2C)c1 +O=C(Nc1ccc(Cl)cn1)c1nc(-c2ccncc2)no1 +COc1cc(OC)cc(C(=O)Nc2sc(C)c(C)c2C#N)c1 +O=C(C1Cc2cc(Cl)ccc2O1)N1CCCC(n2cncn2)C1 +COc1ccc(OCCN(C)C(=O)c2c(C)cc(C)[nH]c2=O)cc1 +Cn1cc(C(=O)OCC2CCOc3ccccc32)cn1 +COc1cccc(C(=O)N2CCCC2CCC(C)C)c1F +CS(=O)(=O)N1CCC(c2csc(Nc3ccccn3)n2)CC1 +CC(C)NC(=O)c1ccccc1NC(=O)CSc1nncs1 +CCOC(=O)Cc1csc(NC(=O)c2cccc(C#N)c2)n1 +CCn1cc(C(=O)N2CCCCC2)c(=O)c2c(N)cccc21 +COc1ccc(Br)c(C(=O)NCC(C)C)c1 +COc1ccccc1C(NC(=O)c1cc(C)oc1C)c1ccccn1 +Cc1cc(NC(=O)NCc2ccc(NC(=O)c3ccco3)cc2)no1 +Cc1cc(CN(C)C(=O)c2c[nH]c3ccccc23)no1 +Cc1ccc(C(=O)Nc2ccc(Br)cc2N)o1 +Cc1nc(C)c(CNc2ncnc3cccc(F)c23)s1 +Cn1ncc(C(=O)NCCc2c[nH]c3ccccc23)c1C(F)(F)F +Cc1cc(S(C)(=O)=O)ccc1NC(=O)c1ccnc(N(C)C)c1 +COC(=O)CN(C(=O)c1cccc(Br)c1)C(C)C +Cc1nnc(COC(=O)c2cccc(OCC(F)F)n2)n1C +Cc1ccc2nc(Cn3cnc(C#N)n3)cc(=O)n2c1 +CC(C(N)=O)n1ccnc1-c1ccc(F)c(F)c1F +COc1ccc(Cl)cc1S(=O)(=O)N1CCc2ccccc2C1 +CN(C(=O)CCc1cccc(F)c1)c1ccc(F)cc1 +CC1(C)CN(CCNc2ccccc2F)CCO1 +CCCC(=O)N1CCN(C(=O)c2cn3ccncc3n2)CC1 +Cc1sc(-c2ccco2)nc1C(=O)Nc1ccnn1C1CCCC1 +O=C(Nc1cccc(NC2CCN(CC(F)F)CC2)c1)c1ccoc1 +O=C(Nc1ccn(-c2ncccc2Cl)n1)NC1CCCCC1 +c1cnc(NCc2nncn2C2CCCCC2)nc1 +CC(CC(=O)c1ccco1)NC(=O)c1scnc1C1CC1 +Cc1noc(C)c1CC(=O)Nc1ccc(Cl)c(C(F)(F)F)c1 +Cc1nnc(C(C)Sc2nnc(-c3ccccc3F)n2N)o1 +Cc1nc(-c2ccc(C(=O)NCc3cccs3)cc2)cs1 +Cn1nccc1C(=O)NC1CC(=O)N(CCc2cccc(Cl)c2)C1 +CCN(CCCO)S(=O)(=O)c1ccc(C)cc1 +CCOc1ncccc1CNC(=O)Nc1ccc(C)cc1F +Oc1ccccc1-c1nnc(SCc2ccncc2)o1 +Cc1ccccc1C(=O)Nc1cc(S(=O)(=O)NC2CC2)ccc1F +O=C(NCCC1=CCOCC1)c1cnn(-c2ccc(F)cc2)n1 +CCOC(=O)c1c(NC(=O)c2cccnc2)sc2c1CCCC2 +Cc1n[nH]c(SCC(=O)N2CC3(C)CC2CC(C)(C)C3)nc1=O +O=C(Nc1ccc(C(F)(F)F)cc1)NC1CCCc2occc21 +CCOc1ncccc1CNC(=O)c1coc(CN2CCOCC2)c1 +COCCOc1ncccc1NC(=O)NCc1ccc(C)c(F)c1 +CCN(C)C(=O)c1cccc(OCc2ccc(F)cc2C(=O)OC)c1 +CSc1ccc(CC(=O)Nc2ccccc2)cc1 +CCC(OC1CCCCC1)C(=O)NCc1ncn(C)n1 +C=CCCC(=O)N(CC)c1ccccc1S(=O)(=O)CC +Cc1ccc(SCC(=O)Nc2nnc(-c3ccncc3)o2)cc1 +CC(Sc1cc(Cl)ccc1Cl)C(=O)N1CCC1 +O=C(NCc1cnn(Cc2ccccc2)c1)C1CCOCC1 +Cc1ccccc1OCC1CN(C(=O)c2ccccc2)CCO1 +OCc1ccc(-c2ccc(Cn3ccnc3)cc2)cc1 +COc1ccc(Nc2nc(N)nc3[nH]cnc23)cc1OC +Cc1noc(C2CCN(C(=O)c3cccc(-n4cnnn4)c3)CC2)n1 +CCCn1cc(C(=O)NC)c(S(=O)(=O)N2CCC(C)CC2)n1 +CC(=O)Nc1ccc2c(c1)nc(C(=O)C(C)C)n2C +CCOC(C)C(=O)N(CC1CCCO1)c1ccncc1 +O=C(NCc1cc2ccccc2o1)c1cn(Cc2ccccc2)nn1 +CCc1onc(C)c1NC(=O)Cc1ccc(-n2cnnn2)cc1 +O=C(NCc1cnn2ccccc12)C1CC=CCC1 +CCCOc1ccccc1NC(=O)CNC(=O)C1CC1 +Cc1nc(CC(=O)Nc2sc3c(c2C#N)CCCC3)cs1 +CC(C)NC(=O)Nc1ccccc1NC(=O)Cc1cccc(F)c1F +Cn1nc(-c2nc3c4cnn(C)c4ncn3n2)cc1C(F)(F)F +CCOC(=O)n1cc(CCNC(C)=O)c2cc(OC)c(C(C)=O)cc21 +CNC(=O)c1cccc(Cn2ccnc2-c2ccccn2)c1 +CCCCc1cc(=O)[nH]c(-c2ccc(CN3CCOCC3)cc2)n1 +CC(=O)Nc1ccc(SCC(=O)NC(C)C)cc1 +CCOc1ccc(-c2n[nH]c(N)c2C)cc1OCC +Cn1cncc1C1NCCc2c(Br)cccc21 +Cc1nc2ccc(NC(=O)N(C(C)C)C(C)C)cc2s1 +CCN1C(=O)COc2cc(NCc3ccc(C)cc3)ccc21 +CC(=O)N(C)c1ccc(NC(=O)c2cccc3ccccc23)cc1 +Cc1nsc(NC(=O)NCc2ccccc2OC(F)(F)F)n1 +Cn1cnnc1-c1ccnc(NC(=O)c2ccccn2)c1 +CC(c1ccsc1)N1CCN(C(=O)c2cccc3[nH]cnc23)CC1 +Cn1cc(CCC(=O)N(Cc2ccoc2)C2CCCCC2)cn1 +CCc1nnc2n1CCN(C(=O)c1cc(-c3ccc(C)s3)[nH]n1)C2 +CNC(=O)NCC(=O)NC(C)c1ccc(C(F)(F)F)cc1 +CCc1nnc(NC(=O)Cn2ncc3c2-c2ccccc2OC3)s1 +CCN(Cc1cccc(F)c1)C(=O)c1ccc(OC)cc1O +COC(=O)c1cc(-c2ccc(N)cc2)nc(N(C)C)n1 +COc1cc(F)ccc1NCc1cnn(-c2ccccc2)n1 +CCN(Cc1nccn1Cc1cccc(F)c1)C(=O)C(C)C +Cc1cccc(NC(=O)N2CCN(CCS(N)(=O)=O)CC2)c1 +Cc1oc(C(=O)NCCN(C)c2ccccc2)cc1S(N)(=O)=O +COCc1c(CO)nnn1-c1cccc2ccccc12 +N#Cc1ccc(Cn2cccc(OCCCO)c2=O)cc1 +O=C(Nc1ccc(F)c(NC(=O)C2CC2)c1)c1cnccn1 +COc1cc(NS(=O)(=O)c2ccc(F)c(C)c2)cc(OC)c1 +CC(C)Cn1cc(NCc2cnc(C(C)C)s2)cn1 +CS(=O)(=O)NC1CCN(C(=O)Nc2ccc(F)c(C#N)c2)CC1 +CCCCN(C)S(=O)(=O)NC(C)c1ccc(C)o1 +CC(C)CC(C#N)N(C)C(=O)c1ccc(Br)cc1 +CN(C(=O)CSc1nnc(CO)n1C1CC1)c1ccccc1 +Cc1ccc(OC(=O)C2CCCN2C(=O)Cc2cccs2)cc1 +COCCOC1C(O)C(CO)OC1n1cnc2c(=O)[nH]c(N)nc21 +CCn1nc(C)cc1C(=O)Nc1c(C)nn(Cc2ccccc2)c1C +COC(=O)CCC(=O)N1CCCC(C(=O)c2ccc3c(c2)OCO3)C1 +CC(=O)Nc1ccc(NC(=O)c2cc3nc(C)ccc3o2)cc1 +Cc1cc(-n2nnc(C(=O)NC3CC3)c2-c2ccncc2)ccc1F +O=C(NCCC(O)c1ccccc1)c1ccc2c(c1)OCCO2 +O=C(Nc1ccc(N2CCCC2=O)c(Cl)c1)c1ccc[nH]c1=O +NC(=O)c1ccc(NC(=O)CCC2CCCC2)c(Br)c1 +CC1CC1c1ccc(CCC(=O)N2CCN(CC(C)(C)O)CC2)o1 +Cc1noc(C)c1CCCNC(=O)N1CCCCCC1 +Cc1noc(NC(=O)Nc2c(-c3ccccc3Cl)noc2C)c1C +CCn1cccc1C(=O)NCC(O)c1ccccc1 +CCOc1cccc(C(C)NC(=O)Nc2cccc(NC(C)=O)c2)c1 +CC(=O)c1ccc(NC(=O)N(C)CC(F)F)cc1C +Cc1ccc2cccc(OC(=O)Nc3ccccc3)c2n1 +Cc1ccc(Cl)c(OS(=O)(=O)c2cn(C)c(=O)n(C)c2=O)c1 +COCCOC(=O)C(C)N1C(=O)C(C)Oc2cccc(N)c21 +CNC(=O)c1cccc(NC(=O)N2CCCC(C)C2)c1C +Cc1nn(C)c(C)c1NC(=O)Cn1nnnc1C(C)(C)C +CC(=O)NCc1nc2ccccc2n1CCOc1ccc(C)cc1 +CC(=O)Nc1cc(NCCCc2ccccc2)ccc1F +CCOc1ccc(NS(=O)(=O)c2cn[nH]c2)cc1Cl +Cc1cc(C(O)C(=O)N2CCc3ccccc32)ccc1F +Cc1noc(COCC(=O)NC2(c3ccccc3)CCCC2)n1 +Cn1cc(Br)c(C(=O)Nc2cc(-c3ccccc3)n[nH]2)n1 +O=c1c2c3c(sc2ncn1Cc1n[nH]c2c1CCC2)CNCC3 +CCOC(=O)N1CCC(NC(=O)COc2ccc(C)cc2)CC1 +Cc1ccc(-c2nnc(Cn3nnc(-c4ccccc4)n3)o2)cc1 +Cn1ccnc1Sc1ccnc2cc(Cl)ccc12 +CCc1cnc(C)nc1N1CCN(Cc2cccc(OC)c2F)CC1 +CCCOc1ncccc1CNC(=O)N1CCCC(C)C1 +Cc1cccc2c(=O)n(CCC(=O)Nc3nnc4ccccn34)cnc12 +CC(C)(C)c1nnnn1CC(=O)N1CCOC2CCCCC21 +CC(C)c1nnc(NC(=O)CSc2nnc(-c3ccco3)n2C)o1 +CCOc1ccc(C(=O)n2cnc3ccccc32)cc1OCC +COC(=O)CC1CCCCN1C(=O)c1ccno1 +C=CCSc1nnnn1-c1cc(C)ccc1OC +O=C(Cc1ccccc1F)NC1CCCc2ccccc21 +O=C(OCCc1cccs1)c1cccc2[nH]ncc12 +COc1ccc(-c2c(C)nn3c(N4CCOCC4)cc(C)nc23)cc1 +CC(=O)c1ccc(NC(=O)CSc2nnc3[nH]c(=O)ccn23)cc1 +Cc1cncc(C2NCCc3ccc(Cl)cc32)c1 +Cn1cc(S(=O)(=O)N2CCC(NC(=O)C3CCCO3)CC2)cn1 +O=C(c1ccc(-c2csc(C3CC3)n2)cc1)N1CCCCCC1 +Cc1csc(S(=O)(=O)Cc2coc(-c3cccs3)n2)n1 +CC(C)c1ncc(Cl)c(C(=O)Nc2cc(F)ccc2F)n1 +CCS(=O)(=O)NCCCNC(=O)Nc1ccc(Cl)cc1 +CC(C)CC1COCCN1C(=O)C(C)NC(=O)CC1CCCCC1 +CC(C)Cn1ncc2cc(C(=O)Nc3nccn(C)c3=O)cnc21 +COc1cccc(-c2nn(-c3ccccc3)cc2C(N)=O)c1 +CCC(C)NC(=O)c1cc(-c2ccc(OC)cc2)n(CC)n1 +Cc1nc(CSc2ccccc2C(=O)NC(C)CO)cs1 +c1cnc(Nc2nc(-c3ccc4c(c3)OCCO4)n[nH]2)nc1 +CC(C)c1cccc(OCC(=O)N(C)C2(C#N)CCC2)c1 +CC(C)c1ccc(C(=O)Nc2nnc(C3CC3)s2)cc1 +CC(C)CNC(=O)N1CCCC(C(=O)N2C(C)CCCC2C)C1 +CN(C)C(=O)N1CCC2(CCCN(C3CCCCC3)C2=O)C1 +CN(C)Cc1cc(=O)n2c(n1)CN(C(=O)C1CCOCC1)CCC2 +Cc1cc(S(C)(=O)=O)ccc1NC(=O)c1cn(C)nc1C +Cc1ccc(OCC#CCNC(=O)NCCc2ccccc2)cn1 +Cc1csc(C(C)NC(=O)COCc2nc(C)no2)n1 +CC(=O)c1ccc(C)c(S(=O)(=O)Nc2cccc(F)c2)c1 +CC(NC(=O)Nc1cc(Cl)ccc1Cl)c1nc[nH]n1 +Cn1cccc1C(=O)OCC(=O)N1c2ccccc2NC(=O)C1(C)C +CCc1nc(NCc2ccccn2)c2cc(CC)sc2n1 +CCn1c(N)nc2cc(C(=O)N3CCCn4nc(C)cc4C3)cnc21 +COc1ccccc1NC(=O)C1CCCN(C(=O)C(C)(C)C)C1 +COC(=O)c1cc2sccc2n1CC(=O)Nc1ccccc1OC +CCC(C(=O)OCc1cc(=O)n2ccsc2n1)c1ccccc1 +CCOc1cc(NCc2ccccn2)nc(C2CC2)n1 +CN(C)c1ccc(Cl)cc1NC(=O)c1ccc2c(c1)OCO2 +COC(=O)CCCOc1c(Cl)cccc1Cl +COc1ccc(NC(=O)c2cc(C)cc(C)c2)cc1N +CNc1snc(C)c1C(=O)NCC1Cc2ccccc2O1 +CC1CCCN(C(=O)c2cccc(Cl)c2Cl)C1 +Cc1cc(CN(C)C(=O)c2c[nH]nc2-c2ccc(F)cc2)no1 +CCOCC(=O)N(C)C1CCN(c2ncnc3ccccc23)CC1 +CCC(CO)(CO)NC(=O)C(c1cccc(F)c1)N(C)C +CC(CC(=O)N1CCNC(=O)CC1)c1ccc(C(F)(F)F)cc1 +Cc1nn(C)c(C)c1CNC(=O)c1ccc2nc(C(C)C)oc2c1 +O=C(c1cc(C(=O)N(Cc2cccs2)C2CC2)c[nH]1)N1CCCC1 +CC(C)CC(=O)N1CCC2(C1)CN(c1ccccc1)C(=O)CN2C +Cc1cc2ccccc2n1CCc1nc(C2CCOC2)n[nH]1 +Cc1noc(C)c1COc1ccc(-c2noc(N)n2)cc1 +CCN(CC)C(=O)CCC(=O)N=c1[nH]nc2ccccn12 +CCOC(=O)CC(C)CNC(=O)Nc1ccc(Cl)c(F)c1 +COc1ccc(CNC(=O)c2c(C)noc2C)c(OC2CCCC2)c1 +Cc1cc(NC(=O)CSc2nnc3n2CCCCC3)no1 +COc1ccccc1NC(=O)c1cc2cccc(OC)c2oc1=O +CC(C)c1ccccc1NC(=O)C1CSc2nccc(=O)n2C1 +CN(CCc1ccccn1)C(=O)c1cc(=O)[nH]c2cc(F)ccc12 +N#CC1(NS(=O)(=O)CCc2ccccc2)CCCC1 +O=C(NCc1nncn1C1CCCCC1)c1cc2sccc2[nH]1 +CCCNC(=O)COc1cccc(CC(N)=O)c1 +CCOC(=O)c1csc(C(=O)NCC(F)(F)F)n1 +Cc1cc(C(O)C(=O)NCc2ccccn2)ccc1F +Cc1ccc(CNC(=O)COc2ncnc3ccccc23)cc1 +CCc1ccc(S(=O)(=O)NC(C)C(=O)NCc2ccco2)cc1 +CCN(CC)C(=O)c1nnc2sc(-c3cccc(F)c3)nn12 +COC(=O)C1CCN(C(=O)Nc2cccc(Br)c2)CC1 +CCc1nc2ccccc2n1C(CC)C(=O)NCCc1cccnc1 +O=C(Nc1ccc(Br)cc1)Nc1ccon1 +O=C(Nc1ccn(CC(F)F)n1)c1c[nH]c(=O)c(Br)c1 +CCC(CC)N(C)C(=O)NCC(C)N1CCOCC1 +CCOc1ccc(OCC)c(NS(=O)(=O)c2cccs2)c1 +CCC1(NC(=O)c2cccc(OCC(F)F)n2)CCC1 +CC1C(C(=O)NC2CCCCC2)C(=O)NC1(C)C +COC(=O)CCNC(=O)c1c(C)nn(-c2ccc(F)cc2)c1C +CNS(=O)(=O)c1ccc(C(C)NC(=O)N2CCCC2)cc1 +N#CCCn1cc(C(N)=O)c(-c2cc3ccccc3o2)n1 +Cc1cc(C)c(C(=O)N2CCCC(C(=O)N3CCC(C)CC3)C2)[nH]1 +Cc1ccc(NC(=O)c2cnn(-c3ccc(F)cc3)c2)cc1C +COc1ccccc1OCCNC(=O)c1cc2c(s1)CCCC2 +N#Cc1ccccc1COc1cccc(Oc2ncccn2)c1 +CC#CC1NCCc2ccc(O)c(Br)c21 +COC(=O)CN1C(=O)COc2ccc(S(=O)(=O)NC(C)C)cc21 +COCCNC(=O)N1CCN(Cc2cscn2)CC1 +O=C(NC1CCCC1)c1ccc(-n2ccnn2)cc1 +COC(=O)c1cc2c(=O)n(-c3ccc(C(C)=O)cc3)ccc2nc1C +COC(=O)CCNc1nc(-c2cccs2)cs1 +Cc1nc(C2CC2)nc2sc(C(=O)OCC3(C)COC3)c(C)c12 +C#CCNC(=O)C(NC(=O)c1ccccc1C)C(C)C +Cc1cc(NC(=O)c2n[nH]c3c2CCCCC3)nn1C +O=C(NCC1CCCO1)C1CCCN(c2ncccn2)C1 +CCCCOc1cnc(NS(=O)(=O)c2ccc(N)cc2)nc1 +COc1ccc(C2CCCCCN2C(=O)c2ccncc2F)cc1 +CCc1ccc(C2COCCN2C(=O)CCC(=O)N(CC)CC)o1 +COc1ccccc1NC(=O)NC(C)C(=O)OC(C)C +CC(C)NC(=O)Cc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1 +O=C(c1csnn1)N1CCCCCC1CC(O)c1ccco1 +N#Cc1csc(CNc2cccc(OCCn3cccn3)c2)c1 +CC(C)CCC(C)NC(=O)Nc1ccccc1CC(=O)N(C)C +CC(=O)NCC(=O)N1CCN(Cc2ccc3c(c2)OCO3)CC1 +COC(=O)C1=C(C)NC(=O)NC1c1cccc(F)c1 +Nc1nc(N)nc(Cn2nnn(-c3ccccc3Cl)c2=O)n1 +CC(CO)C(C)NC(=O)Nc1ccc(Oc2ccccc2C#N)cc1 +COC(C)C(=O)Nc1ccc(C(=O)NC2CC2)cc1 +CCN(Cc1ccc(OC)cc1)S(=O)(=O)N(C)C(C)C +CC(C)C(NC(=O)Nc1cccc(CS(N)(=O)=O)c1)C(N)=O +CCc1nnnn1-c1ccccc1NC(=O)COc1ccccc1F +CCOc1ccc(CC(=O)Nc2ccc3c(c2)CC(=O)N3C)cc1 +COC(=O)C1CN(C(=O)c2c[nH]c3cccc(F)c23)CCO1 +Cc1ccc2oc(=O)c(S(=O)(=O)c3cccc(C#N)c3)cc2c1 +Nc1ccc(=O)n(CC(=O)Nc2ccc(Oc3ccccc3)cc2)c1 +C=CCOCc1cncc2c1CCN(C(=O)N1CCCC1)C2 +CC(NC(=O)c1cccnc1)c1ccc(Br)cc1 +Cc1ncc(CNC(=O)Nc2ccc(Br)cc2F)s1 +COc1ccccc1CCC(=O)Nc1ccc(-n2cnnn2)cc1 +COC(CNS(=O)(=O)C1CC1)c1ccccc1C +O=C(COc1cccc2[nH]ccc12)Nc1ccc2c(c1)OCO2 +COCCCNC(=O)Cn1nc(-c2ccco2)oc1=O +COCCNC(=O)c1ccc(N)c(OCC(C)C)c1 +Cc1nc(C)c(C(=O)NCCc2c[nH]c3ccc(F)cc23)s1 +CCOC(=O)c1cnc(Cc2cccc(C)c2)nc1N +O=C(CS(=O)(=O)c1nc(-c2ccccc2)cs1)N1CCCC1 +O=C1CC2C(CCN2S(=O)(=O)C2CC2)N1c1ccsc1 +Cc1cnn(CC2CCCN2C(=O)c2nc(C(C)C)ncc2Cl)c1 +COc1ccc(C(=O)CSc2nnc(C)s2)cc1C +Cc1noc(C)c1C(C)NC(=O)c1c[nH]nc1-c1cccc(Cl)c1 +CCOc1ccccc1C(=O)NCC(=O)N(C)Cc1cnn(C)c1 +COc1cccc(CNC(=O)c2cnn3c4c(cnc23)CCCC4)c1 +COc1ccc(OCCNC(=O)c2ccc(N)cc2)cc1 +COc1ccc(C(C)NC(=O)c2cc(C)n(C(C)C)c2C)c(OC)c1 +Cn1ccnc1C(NC(=O)Nc1ccc(F)cc1F)c1ccccc1 +CCOC(=O)c1cnn2c(N)c(C(=O)Nc3cccc(C)c3)nnc12 +CN1CCOC2CN(Cc3cc4ccccc4s3)CC21 +Cn1nc(C(=O)N2CCCC2c2nc3ccccc3s2)ccc1=O +COc1ccccc1CC(=O)Nc1ccc(OC)c(OC(F)F)c1 +Cc1cc(C(=O)NCc2ccn(-c3ccc(F)cc3)n2)no1 +Cc1sc2ncn(CCC(=O)N3CCNC(=O)CC3)c(=O)c2c1C +COc1ccc(CCC(=O)NC(C)c2ccccc2)cc1OC +CC(C)CS(=O)(=O)N1CCC(Nc2ncc(F)cn2)CC1 +C=CCNC(=O)C1(c2ccc(NC(=O)CC(C)C)cc2)CCC1 +O=C(NCCNC(=O)c1cc2ccccc2[nH]1)c1ccc2[nH]ccc2c1 +COc1ccc(C(=O)c2c[nH]c3ccccc3c2=O)cc1OC +CSc1ccc(NC(=O)NC(C)c2nnc3ccccn23)cc1 +CC(C)NC(=O)COC(=O)c1ccc(F)cc1N +CC(=O)Nc1cccc(NC(=O)c2ccc(C)c(C)c2)c1C +O=C(OCCn1nc2ccccn2c1=O)C1CCC1 +Cc1[nH]ncc1CCCNC(=O)CCc1cnn(C)c1C +CCC(C)NC(=O)CN1CCOc2ccc(N)cc21 +COc1cccn(CC(=O)N(C)CC2CCOC2)c1=O +Cc1cc(Br)ccc1NC(=O)CCc1ccccn1 +COc1ccccc1NC(=O)N1CCn2cccc2C1C(C)C +Cc1cc(C)n2ncc(C(=O)Nc3ccc4c(c3)OCO4)c2n1 +O=C(NCc1nccc(N2CCCC2)n1)c1c(F)cccc1Cl +CC(NC(=O)N(C)C(C)c1ccc(F)cc1)C(=O)N1CCCCC1 +COC(=O)c1ccc2nc(Cc3ccc(F)cc3)nn2c1 +Cc1cnn(CCNc2ncnc3sccc23)c1 +O=c1c(=O)n(Cc2cccc(Cl)c2)ccn1CCc1ccccc1 +O=C(c1c[nH]nc1-c1ccccc1F)N1CC2CCCCC2C1 +COCCN(Cc1ccccc1)C(=O)CC1C=CCC1 +CNC(=O)c1ccc(Cl)cc1NC(=O)c1ccccc1 +O=C(c1ccc2[nH]c(C3CCCC3)nc2c1)C1CC1 +CCOC(=O)N1CCC(NC(=O)c2ccc(C)cc2C)CC1 +N#CCc1ccc(NC(=O)Cc2ccccc2F)cc1 +CCCn1cc(NCc2ccc(-c3cccnc3)o2)cn1 +NC(=O)c1cc(Cl)ccc1OCC(=O)N1CCc2ccccc21 +CC(COc1ccc2c(c1)OCO2)NC(=O)c1c(F)cccc1F +O=C(Nc1cc(C(F)(F)F)c[nH]c1=O)C1CC(=O)N(CC2CC2)C1 +CCOC(=O)c1cnn(-c2cccc(Cl)c2)c1C +COCc1cc(=O)[nH]c(Nc2cc(F)ccc2Cl)n1 +CC(C)OCCCNC(=O)c1ccc(-n2ccnn2)cc1 +OCCc1nnc(COc2ccc(Cl)cc2Cl)o1 +CCn1c(SCC(=O)N(c2ccccc2)C(C)C)nnc1C1CC1 +Cn1c(=NC(=O)Cc2cn3ccsc3n2)[nH]c2cc(Cl)ccc21 +CC(NS(=O)(=O)c1cccc(C#N)c1)c1nnc2n1CCCCC2 +COc1cc(OC)cc(C(=O)NC(CO)CC(C)C)c1 +CN(CC(=O)NC1CC1)C(=O)CNc1ccc(F)c(C(F)(F)F)c1 +CCOc1ccc(Cc2nc3cc4c(cc3[nH]2)OCCO4)cc1 +CCOCCCNC(=O)c1cn2ccnc(-c3ccc(F)cc3)c2n1 +Cc1csc(N2CCCN(C(=O)c3ccc(=O)[nH]c3)CC2)n1 +CCCC(=O)Nc1ccc(NC(=O)c2cccs2)cc1 +COc1ccc(NC(=O)COc2ccccc2)cc1OC +COc1ccccc1CNC(=O)Cc1cc(-c2ccccc2F)on1 +C#CCOCCC(=O)N(C)C1(C(=O)OC)CCCCC1 +CCc1onc(C)c1NC(=O)c1sc(COC)nc1C +C=CCOc1cccc(NC(=O)c2cnc(C)cn2)c1 +CNc1c(F)cccc1C(=O)NCC1CCCO1 +CC(=O)c1cc(F)ccc1OCC(=O)N1CC(=O)Nc2ccccc21 +N#Cc1ccccc1OCC(=O)NC1CCOc2ccccc21 +Cc1cc(N)nn1CC(=O)Nc1ccc(F)c(F)c1 +CN(C)c1c(Cl)cccc1NC(=O)NCCCn1cccn1 +O=C(Cc1noc2ccccc12)Nc1ccc(N2CCCC2)nc1 +CC1CNC(c2ccccc2)CN1C(=O)c1ccco1 +CCc1onc(C)c1NC(=O)c1cc(C2CC2)n(C(C)(C)C)n1 +CCN(CC)C(=O)c1cc(C(C)(C)C)n2nc(C)nc2n1 +CCCn1cc(S(=O)(=O)N(C)Cc2cn(CC)nc2C)cn1 +CCC1CCCN(C(=O)C(Cc2cccc(OC)c2)NC(C)=O)C1 +COc1ccccc1NC(=O)CSc1nc(C2CCCO2)n[nH]1 +COc1ccc(OC)c2c1CN(CC(=O)NC1CCCC1)CC2O +CCN(CC)C(=O)CCC(=O)NC1CCC(C)(C)c2ccccc21 +O=C(COC(=O)c1ccc(F)cc1)Nc1ccccn1 +OCC1CCCCC1Nc1ncc(Br)cn1 +CC(C)c1cc(-c2nn3c(-c4cnn(C)c4)nnc3s2)nn1C +Cn1cnnc1SCC(=O)c1ccc(C#N)cc1 +Cc1cccc(CC(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +CCOc1ccccc1NC(=O)CSc1cc(C)ncn1 +Fc1ccc(-c2nnn(Cc3nc4ccccc4s3)n2)cc1 +COc1ccc(Br)c(C(N)C(F)(F)F)c1 +Cc1nc(COc2cccc(C(=O)NC3C=CC(CO)C3)c2)no1 +CC1CCC(C(=O)Nc2ccc3nc4n(c(=O)c3c2)CCCC4)CC1 +Cc1[nH]nc(CCC(=O)N(C)Cc2cc(-c3ccncc3)no2)c1C +CC(C)(CNC(=O)NCC(C)(C)N1CCOCC1)c1ccncc1 +Cn1cc(C(=O)Nc2cccc(O)c2)c(=O)c2cccc(F)c21 +CCOC(=O)c1cc(C#N)c(SCC(=O)NC2CCCC2)nc1C +O=C(NCc1ccc2c(c1)OCCO2)c1ccccn1 +Cc1nc(CNC(=O)N2CCOC(c3ccsc3)C2)oc1C +COc1ccc(C)cc1CCNC(=O)C(N)c1ccccc1 +CC(Sc1nnc2n1CCCCC2)C(=O)NCc1cccs1 +Cc1csc(N2CCN(CCC(=O)NC3CCCCC3)CC2)n1 +Cc1nc(CN(C)C(=O)c2ccnc(-n3ccnc3)c2)cs1 +CCN(CC)c1ccc(C(=O)N2CCCCC2C)cc1 +O=C(Nc1cccc2ncccc12)c1nnc2ccccc2n1 +Cc1nc(-c2ccccc2)ncc1-c1nc(C2CCOC2)no1 +CCOC(C)C(=O)Nc1ccccc1C(=O)N(C)C1CCCCC1 +CC(=O)N1CCN(C(=O)COc2nnc(-c3ccccc3)o2)CC1 +COc1cc(N2CC3(CCN(S(C)(=O)=O)C3)C2)ncn1 +COCC(C)N1CC(C(=O)Nc2cccc(F)c2)CC1=O +O=C(c1cn[nH]c1)N1CCOC(c2ccccc2)C1 +CCc1ncc2c(n1)CN(C(=O)CCS(=O)(=O)c1ccccc1)C2 +N#Cc1ccc(NC2CCCCNC2=O)cc1Cl +O=C(Cn1c(=O)oc2cc(Cl)ccc21)Nc1ccccc1Cl +Cc1ccc(C(=O)Nc2ccc(Cn3cncn3)cc2)c(=O)n1C +Cn1cc(N2CCC(Nc3ccc(C(F)(F)F)c(C#N)c3)C2=O)cn1 +Cc1cc(C(=O)NCC(=O)NCc2ccccc2F)nn1C +COc1ccc(CCNC(=O)c2cccc(N)c2C)cc1 +CCOC(=O)c1[nH]c(=O)[nH]c1Cn1nc(C)cc1C +O=C(COC(=O)c1ccc(O)cc1)Nc1cccc(C(F)(F)F)c1 +C#CCn1nc(CO)cc1-c1ccccc1OCC +O=C(CCCOc1ccccc1Cl)NCc1cscn1 +CC(C)c1nn(C)c(N(C)C)c1CNCC(O)c1ccccc1 +O=C(CNC(=O)c1ccccc1F)NCC1COc2ccccc2O1 +CCS(=O)(=O)NCC(=O)OCc1ccccc1 +CCCCCCC(=O)Nc1cccc(C(=O)NC)c1 +CC(C)CCC(=O)N1CCN(C(=O)Nc2ccncc2)CC1 +CN(C)C(=O)COc1cccc(NC(=O)c2ccc(F)nc2)c1 +CCN(CC(C)C)S(=O)(=O)c1c(N)ccc(C)c1C +Nc1cccc(OCCNC(=O)c2ccc(F)c(F)c2)c1 +CCCNC(=O)c1cccc(NCC(=O)N2CCCCC2)c1 +CNC(=O)NC(CC(=O)OC)c1ccc(OC)c(OC)c1 +CC(C)n1cc(O)c(=O)cc1CN1CCN(CCO)CC1 +COCc1cccc(NC(=O)c2ccc(OCC(F)F)nc2)c1 +CN1CCOc2ccc(NC(=O)c3ccccc3)cc2C1=O +O=C(CC1CCCC1)Nc1ccc(C(=O)N2CCCC2)cc1 +COc1ccc(NC(=O)c2nn(C(C)C)c(=O)c3ccccc23)cn1 +Cc1cc(S(C)(=O)=O)ccc1NCc1ccn(-c2ccccc2)n1 +Cc1cccc2c(=O)cc(C(=O)Nc3ccccc3F)oc12 +CC(CC#N)N(C)C(=O)Nc1cnc2c(c1)c(=O)n(C)c(=O)n2C +COc1cc2nc(C3CCC3)n(CC(C)C#N)c2cc1OC +COC(=O)c1ccc(COc2ccccc2NC(C)=O)cc1 +COc1cccc(C(=O)NCC(O)c2ccco2)c1 +Cc1csc(NC(=O)C2C(=O)NCC2c2ccccc2)n1 +CCOCC1CN(C(=O)c2cscn2)Cc2nnn(CC3CC3)c21 +COc1cccc(NC(=O)c2cc(F)cc3[nH]cnc23)c1 +CC(C)Cc1n[nH]c2c1CN(c1nnnn1-c1ccccc1)CC2 +Cc1ccc(C(=O)Nc2ccccc2-n2cncn2)cn1 +CC(C)(C)OCc1cccc(CNC(=O)c2ccc(C(N)=O)cc2)c1 +CSc1nsc(NC(=O)c2ccc(NC(=O)C3CC3)cc2)n1 +COc1cccc(C(=O)Nc2ccc(Oc3ncccn3)cc2)c1F +CCCC(CC(=O)NC)c1ccc2c(c1)OCCO2 +O=C1CCc2cc(C(=O)Nc3ccc(N4CCCC4=O)cc3)ccc2N1 +COc1cccc2cc(C(=O)Nc3nc(C)no3)oc12 +Cc1ccccc1Cn1cc(NC(=O)c2cccs2)cn1 +O=C(c1nn2ccccc2c1Cl)N1CCN(c2ccccc2)CC1 +Cc1cccc(C(=O)NC(C)C(=O)NC(C)Cc2cccs2)c1 +O=C(c1cccc(Cl)c1)N(CC1CCCO1)c1ccncc1 +COc1ccc(C(NC(=O)CCC2CC2)C2CCOCC2)cc1 +COc1cccc(C(=O)C2CCN(C(=O)C3CC3)CC2)c1 +Cn1cnc(CNC(=O)Nc2cc(F)ccc2OC(F)F)n1 +CCOCC12CCCOC1CCN(C(=O)c1ccc3c(c1)OCO3)C2 +Cc1nnc(NC(=O)C2CC2c2ccc(F)cc2)s1 +COc1ccc(OC(=O)c2cn(C)nc2C(F)(F)F)cc1 +Cc1ocnc1CNC(=O)Nc1ccc(-c2nc3ccccc3o2)cc1 +Cc1ccc(C(O)C2CC(=O)N(C(C)(C)C)C2)cc1 +O=C(COCc1cc(-c2cccs2)on1)Nc1ccccc1F +CCOC(=O)c1c(NC(=O)CC)sc2c1CCCC2=O +COc1ccc(C(=O)N2CC(C)C(C)(O)C2)cc1N1CCOCC1 +CCC1(CNC(=O)N2CCCC2c2nnc3n2CCCCC3)CC1 +COc1ccc(CNC(=O)CSc2nncs2)cc1OC +CCN(C)C(=O)Cc1cc(=O)oc2cc(OC)ccc12 +COC(=O)CC(C)S(=O)(=O)c1ccc(F)cc1 +CC(=O)N1CCC(C(=O)NCC(O)C2CC2)CC1 +Cc1ccc(N2CC(C(=O)NCc3cscn3)CCC2=O)cc1C +CSc1ccc(NC(=O)CCS(=O)(=O)c2ccc(C)cc2)cc1 +COc1cccc(CNc2nnc(Cc3ccccc3F)o2)c1 +CCCC(O)c1cc(F)c2c(c1)C(NC(=O)C1CC1)CCO2 +Nn1c(SCC(=O)Nc2ccc3c(c2)CCC3)nnc1C1CC1 +O=C(CCSc1ccccc1F)N1CCCc2cccc(O)c21 +Cc1cc(C)n(CCCNC(=O)NCC(C)(C)c2ccncc2)n1 +O=C(Cc1cc(F)ccc1F)NCc1cccc(-n2cccn2)c1 +COc1nc(NC(=O)c2cc(C)c(F)cc2F)n[nH]1 +CC(NC(=O)CNC(=O)OC(C)(C)C)c1nncn1C +Cc1ccc(OCCC(=O)NCc2cccnc2)cc1C +Cc1nc(CC(=O)N2CCc3ccccc32)cs1 +CCOC(=O)c1[nH]c(C)c(CNc2cccc(OC)c2)c1C +Cc1cc(C(=O)NCC2CC3C=CC2C3)c2c(C)noc2n1 +NC(=O)C1CCN(c2cc(C(F)(F)F)nc3ccccc23)CC1 +Cc1cc(C(=O)NC(C#N)C(C)(C)C)nc2c1c(=O)n(C)c(=O)n2C +CCc1nc(C)c(C(C)N(C)Cc2ccccc2NC(C)=O)s1 +O=C1COc2cc(NC(=O)c3cnccn3)ccc2N1 +CCc1cccc(OCCN2C(=O)Cc3cc(N)ccc32)c1 +O=C(COc1nnc2ccccn12)Nc1ccc(Cl)cc1 +Cn1cc(C(N)=O)cc1C(=O)NCC(=O)Nc1ccccc1 +CNC(=O)C(CC(C)C)NS(=O)(=O)c1ccccc1F +Cc1ccc(C)c(NC(=O)CSc2nc(=O)[nH]c3c2CCCC3)c1 +CC1(C)Cc2c(sc3ncn4nc(-c5cccnc5)nc4c23)CO1 +COc1ccccc1S(=O)(=O)NC(C)c1ccc(C)o1 +COc1ccc(C(=O)N2CCn3c(C)nnc3C2)cc1F +CCN(Cc1ccc2c(c1)OCO2)C(=O)c1csnn1 +O=C(NCc1ncc[nH]1)Nc1ccc(S(=O)(=O)NCC2CC2)cc1 +Cc1cc(=O)[nH]c(NCCNC(=O)C(c2ccccc2F)N(C)C)n1 +CCOc1ccc(S(=O)(=O)Nc2ccncc2)cc1C +O=C(CCNC(=O)c1ccc(Br)cc1)OC1CCCC1 +COCCCOc1ccc(S(=O)(=O)N(C)C)cc1N +COc1nccnc1N1CCC(NC(=O)Cc2c(C)noc2C)C1 +c1csc(-c2nc(CNc3ccc4cc[nH]c4n3)no2)c1 +O=C(CCCc1ccccc1)NCc1cc[nH]c(=O)c1 +CC(C)Cc1cc(-c2nc(-c3cn(C)cn3)no2)[nH]n1 +C=CCNC(=O)CSc1nnc(-c2ccc(Cl)cc2)n1N +CCOC(CC)C(=O)N(CC)Cc1cccc(F)c1 +CC1COCCN1C(=O)c1ccccc1OCc1ccc(F)cc1 +COc1ccc(CCNC(=O)CCn2ncc3cccc(C)c32)cc1 +CCC(C)C(NC(N)=O)C(=O)NCC(=O)NC(C)(C)C +CCCn1c(C)nnc1CSc1nnc(C)n1-c1cccc(C)c1 +Cc1nc(N2CCN(Cc3cccc4[nH]ccc34)CC2)sc1C +CC(=O)C(C)N1CC(C)Nc2cc(F)c(F)cc21 +CCCCCNS(=O)(=O)c1ccc(N2CCCCC2=O)cc1 +C#CCNC(=O)CNC(=O)NCC1(c2ccc(F)cc2)CCC1 +CC(=O)NCCNC(=O)N1CCC(Oc2cc(C)ccc2C)CC1 +Cc1cc(NC(=O)c2ccc(-c3cscn3)cc2)n(C)n1 +CCOc1cccc(C(=O)Nc2cccc(F)c2)c1 +CCc1ccc(C(=O)C(C)Sc2nnc(CO)n2C2CC2)cc1 +Cc1nc2ncnn2c(C)c1CCC(=O)NC(C)c1c(C)noc1C +CC(=O)NCCNC(=O)c1ccc2c(c1)OCCCO2 +CC1CCC(NC(=O)CCCc2nc3ccccc3c(=O)[nH]2)CC1 +Cc1cc(SC(C)C(=O)N2CCNCC2)ccc1F +Cc1cc(C(C)NC(=O)c2ccc(=O)n(C)c2)c(C)o1 +COc1ccc(NC(=O)CNC(=O)CNC(=O)c2ccco2)cc1 +N#Cc1ccc(OCC(=O)Nc2cccc(Cl)c2)cc1 +COCc1cc(C)nc(SCc2cccc(F)c2)c1C#N +Cc1nc(C2CCCN(C(=O)C(C)OCC3CCCCO3)C2)no1 +CC(C)c1ccc(C(O)CCN2CCOCC2)cc1 +Cc1nn2c(=O)cc(COc3ccc(C)c(C)c3)nc2s1 +CSc1cc(C(=O)Nc2ccc(F)c(F)c2F)ccn1 +CN1C(=O)c2oc3ccc(Cl)cc3c(=O)c2C1c1cccc(O)c1 +Cc1ccc(C(=O)NC(C(=O)Nc2cc(C(C)C)n[nH]2)C(C)C)cc1 +Cc1ccc2c(c1)c(C(=O)NCCCn1nc(C)nc1C)nn2C +N#Cc1ccc(-c2noc(-c3ccc(OC(F)F)cc3)n2)nc1 +CCc1nnc(NC(=O)Cc2ccc(C)c(OC)c2)s1 +Cc1nn(C)c2nc(N3CCCC4(CCOCC4)C3)sc12 +CC(C)CC1CN(C(=O)C2CC2)C(c2ccccc2)CN1 +CCC(CC)C(CNC(=O)N1CCNC(=O)C1)N1CCOCC1 +Cn1nc(CCC(=O)Nc2ccccc2Br)ccc1=O +NC(=O)c1c2ccccc2c(N)n1C(=O)c1ccc(F)cc1 +COCCNC(=O)c1cc2cc(OC)ccc2oc1=O +CCn1c2ccccc2n2c1nn1c(SC)nnc12 +O=C(NCC(O)c1ccccc1)Nc1nncs1 +COCCCN(C)C(=O)CNC(=O)c1ccco1 +CNC(=O)NCC(=O)NC(C)c1c(F)cccc1OC +O=C(NC1CCN(c2c(F)cccc2F)C1=O)c1csnn1 +N#Cc1cccc(NC(=O)NCc2ccnc(OCC3CC3)c2)c1 +CCOC(=O)c1n[nH]nc1Nc1ccccc1Cl +CCCCN(C(=O)Cn1nnc2ccccc2c1=O)C(C)CC +COc1ccc(Nc2nc(C3CCOCC3)cs2)cn1 +CCOC(=O)CSc1ccc(N)cc1C(F)(F)F +CCc1nc(NC(C)c2ccccc2)cc(OC)n1 +CS(=O)(=O)c1ccccc1CC(=O)c1ccccc1 +CC(C)N(CCC#N)C(=O)c1cc(Br)c[nH]1 +COc1ccccc1SCC(=O)Nc1sccc1C(N)=O +Cc1nc(C(=O)N2CC3CN(S(C)(=O)=O)CCOC3C2)cs1 +CCN(CCC(=O)OC)C(=O)c1cc2ccccc2[nH]1 +CCOc1ccc(F)c(C(=O)NC(CC)C2CCCO2)c1F +COc1ccc(C2(CNc3ncccc3C#N)CCOCC2)cc1 +O=C(NCCc1nc2ccccc2[nH]1)NCc1ccccn1 +CCN1CC(C(=O)Nn2cnc3ccccc32)CC1=O +Cc1cc(Br)ccc1C(=O)OCCN1CCCC1=O +Cc1cc(NC(=O)COc2cccc3ccccc23)no1 +Cc1nc(-c2cccc(OCC(=O)Nc3ccc(F)cc3)c2)no1 +COCC(O)CN(C)c1ccccc1S(C)(=O)=O +CCN(CCO)C(=O)c1cc(SC)ccc1Cl +N#Cc1cc(-c2ccncc2)n(CCCC(N)=O)n1 +CCCN1C(=O)c2ccccc2C1(O)c1ncc[nH]1 +COc1ccsc1C(=O)N1CCN(C2CCCC2O)CC1 +CCc1noc(CC)c1CNC(=O)Nc1ccc2c(c1)C(=O)NCC2 +Cc1cc(C(=O)NC(C)Cn2c(=O)oc3ccccc32)on1 +O=C(Cc1cccc2cccnc12)NCc1cc[nH]n1 +O=C(N=c1[nH]c2ccccc2[nH]1)c1cc(Br)c[nH]1 +O=C(CCc1nc2ccccc2s1)NCc1ccc2c(c1)OCO2 +Nc1ccc(F)c(NC(=O)CN2CCOC2=O)c1 +Cc1n[nH]c(C)c1N1CCN(C(=O)Nc2ccc(F)cc2)CC1 +CC(C)COc1ccc(-c2c[nH]c(N)c2C#N)cc1 +CCn1nc(C)c(NC(=O)Nc2cc(-n3cccc3)ccc2F)c1C +Cc1ccc(CCCC(=O)Nc2ccnc(C)c2)cc1 +CSc1cccc(NC(=O)CSc2ncnc3nc[nH]c23)c1 +CCn1c(C2CCCN2C(=O)c2cscn2)nc2ccccc21 +CC(C)CN(C(=O)COc1cccc(N2CCCC2=O)c1)C1CC1 +Cc1ccccc1CC(=O)Nc1cccc(OCC(=O)N(C)C)c1 +COc1ccc(-c2nccn2Cc2ccccc2C#N)cc1 +N#CCCN(CC1CC1)C(=O)c1ccc(Oc2ccncc2)cc1 +COc1ccc(NC(=O)c2ccc(-n3ccnc3)cc2)cc1 +Cc1cc(C)cc(OCCN(C)C(=O)CCc2c(C)n[nH]c2C)c1 +Cc1cnc(Nc2cccc(C3CCCN3C(=O)CO)n2)s1 +O=C(Nc1cccc2cccc(NC(=O)c3ccco3)c12)c1ccco1 +CCN(CC)C(=O)Nc1ccc(C(=O)N2CCOCC2)cc1 +CCN(CC)C(=O)CNc1cc(C(=O)N(C)C)ccc1OC +O=C(C1CC=CCC1)N1CC(c2nc3ccccc3[nH]2)C1 +COC1CCCCC1OC(=O)c1cccc(S(C)(=O)=O)c1 +O=C(OCC(=O)N1CCc2ccccc21)c1cnn(-c2ccccc2)n1 +CCCOc1ccc(C(=O)NCc2c(C)nn(CC)c2C)cc1 +O=C(NC(c1cccs1)C1CCCC1)c1cn2cccnc2n1 +CN(C)C(=O)c1cccn1-c1ncc(C(F)(F)F)cc1Cl +Cc1nc(C)c(C(=O)Nc2ccc3c(c2)NC(=O)CS3)s1 +COC(=O)N1CCc2ccc(NC(=O)c3cccn(C)c3=O)cc2C1 +Cc1ccc(C(=O)Nc2ccn(CCc3ccccn3)n2)c(C)c1 +Cc1nc(NCc2ccccc2)sc1C(=O)NCc1ccco1 +O=C(Cc1ccc(F)cc1)NCC1CN2CCCCC2CO1 +Cc1cc(COC(=O)CCn2nc(-c3cccs3)oc2=O)no1 +CCC(OC(=O)c1cccs1)C(=O)NCc1ccc(C)cc1 +Cc1ccc(CNc2nc(NCCO)nc3c2cnn3C)cc1 +CCC(C)C(C)Nc1cc(S(N)(=O)=O)ccc1OC +O=C(Nc1cc2c(cc1Cl)OCCO2)N1CCOCC1C1CC1 +NC(=O)CNC(=O)c1ccccc1CSc1nc2ccccc2o1 +COC(=O)C(NC(=O)Cc1ccc(C)s1)c1ccccc1 +CS(=O)c1ccc(C(=O)Nc2ccc3c(c2)OCCO3)cc1 +CCOc1ccc(S(=O)(=O)NCc2ccco2)cc1Cl +CCCNS(=O)(=O)c1cc(-c2nnc(C)o2)cs1 +O=C(Nc1cccc(C(=O)N2CCCC2)c1)c1n[nH]c2ccccc12 +CSc1nsc(NC(=O)COc2ccccc2F)n1 +COCCNC(=O)c1cc(-c2cccc(O)c2)on1 +COC(=O)C1CCN(C(=O)Cc2coc3cc(C)c(C)cc23)CC1 +CCN(CC)c1ccc(C(=O)OCC(N)=O)cc1 +CC(=O)N1CCc2ccc(S(=O)(=O)NC3CCCCC3)cc21 +Nc1cccc2oc(-c3ccc(O)cc3)cc(=O)c12 +CC(C)CN1CCOC(CNC(=O)c2cccc(C#N)c2)C1 +COc1c(OC(F)F)ccc2c1C(C1CC=CC1)NCC2 +Cc1nn(C(C)C)c(C)c1S(=O)(=O)N(C)Cc1cccs1 +O=C(OCC1CCCO1)c1cc(Br)ccc1O +OCC1OC(Nc2cccc3ccccc23)C(O)C(O)C1O +COCC(O)CC1=NS(=O)(=O)c2ccccc21 +Cc1cc(C)cc(C(=O)OCCOc2ccc(S(N)(=O)=O)cc2)c1 +CC(=O)c1c(C)[nH]c(C(=O)Nc2cccnc2-n2ccnc2C)c1C +CCC1c2ccsc2CCN1C(=O)NCCNc1ncccn1 +Cc1c(C(=O)N2CCN(Cc3nc4ccccc4[nH]3)CC2)cnn1C +CCc1nc2n(n1)CCCC2NC(=O)COc1ccc(Cl)cc1 +CCn1nc(C(=O)Nc2cc(C#N)ccc2Cl)ccc1=O +Cc1cc(SC(C)C(=O)c2ccc(F)cc2)n(C)n1 +Cc1ccc(C(C)NC(=O)CCNc2ccccc2)s1 +CCc1noc(CC)c1CC(=O)Nc1ccc(NC(N)=O)cc1 +CN(C)C(=O)CSc1nc2ccc(Cl)cc2[nH]1 +C(=Cc1nc2ccccc2[nH]1)c1nc2ccccc2[nH]1 +C=CCN(CC=C)C(=O)c1ccc(NC(=O)c2sccc2C)cc1 +Cc1cc(CNC(=O)c2cn(Cc3cccc4ccccc34)nn2)n[nH]1 +COc1ccc(CN(C)C(=O)c2c(F)cccc2F)cc1F +Cc1c(-c2ccnc(N3CCc4ccccc43)n2)nnc2ncnn12 +Cn1cnc(-c2ccc(F)cc2)c1NC(=O)COC1CCCC1 +Cc1cc(C)c(SCC(=O)N2CCCC(C(N)=O)C2)c(C)c1 +CCCC(C)(NC(=O)Cc1c(F)cccc1F)C(=O)OC +CC(Oc1ccccc1C(C)C)C(=O)Nc1cccnc1 +CCN1CCc2nc(NC(=O)c3ccc(C)[nH]c3=O)sc2C1 +COc1ccc(Cl)cc1C(=O)Nc1nnc2n1CCS2 +O=C(NCc1ccc(COCC(F)(F)F)cc1)c1ccccn1 +COc1ccc(OCCN(C)C(=O)Cc2ccc(F)c(F)c2)cc1 +CCC(CO)NC(=O)C1CC(=O)N(c2ccc(F)c(C)c2)C1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1cc(C)n(C2CC2)c1C +CCc1nnc2ccc(C(=O)N3CCN(CC)CC3)cn12 +CCn1cc(C(=O)Oc2cccc(-n3cccn3)c2)cn1 +O=C(COCc1ccccc1)N1CCC(OCc2cccnc2)CC1 +CN(CCc1ccccn1)C(=O)NC1CCc2cc(F)ccc21 +COCc1c(C#N)nnn1Cc1ccc(C(C)C)cc1 +CC(c1ccc(-n2cnc3ccccc32)cc1)N(C)C(=O)c1ccc[nH]1 +Cc1ncsc1-c1cc(-c2ccc(C#CCO)cc2)c(C#N)c(N)n1 +CSc1nc2n(n1)CC(C(=O)Nc1ccccc1)=C(C)N2 +CCC1(C)C(=O)N(CCC(C)C)c2cc(N)ccc2N1C +COC(=O)C1(NC(=O)C2CC2c2ccccc2)CCCC1 +Cc1ccc(C)c(C(=O)NCc2noc(C3CCCCC3)n2)c1 +CCN(CC)C(=O)CSc1nncn1-c1ccc(OC)cc1 +NC(=O)c1cc(Cl)ccc1OCCOCCO +Cc1cn2c(CN(C)C(=O)C3CCc4cn[nH]c4C3)c(C)nc2s1 +CCS(=O)(=O)c1ccc(NC(=O)Cc2cccs2)cc1 +C=C(C)Cn1c(CNC(=O)COC)nc2ccccc21 +COc1cccc(C(CNC(=O)c2snnc2C)OC)c1 +NCc1cc(=O)[nH]c(COc2ccc(Cl)cc2Cl)n1 +C=CCCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1 +CC(O)(CNS(=O)(=O)c1ccc2cn[nH]c2c1)c1ccsc1 +Cc1ccc(C)c(C(=O)N2CCN(S(=O)(=O)N(C)C)CC2)c1 +COCCOc1ccc(C(=O)N(C)C(C)c2ccco2)cc1 +Cc1cccnc1CN1CCN(C(=O)c2cnn(C)c2)CC1 +CC(=O)N1CCC2(CC1)NC(=O)c1ccccc1O2 +CCCC(=O)NCC1CCCN(C(=O)c2ccc(F)c(F)c2)C1 +Cn1ccc2c(-c3cc4c(cc3C(N)=O)OCO4)ccnc21 +Clc1ccc(OCc2nc(CNCc3cccnc3)cs2)cc1 +Cc1nc2ccc(NC(=O)c3ccc(=O)n(C)n3)cc2s1 +COc1ccc2cccc(NC(=O)c3cc(C)cs3)c2n1 +Cc1nc2ncnc(N)c2c(-c2ccccc2Cl)c1C +CNC(=O)N1CC2CC(C(=O)Nc3ccc4c(c3)OCO4)C(C1)O2 +CC(NC(=O)c1ccc(Cl)c(N)c1)c1cccs1 +N#CCCSc1ccccc1NC(=O)C1CC1c1ccc(F)cc1 +O=C(NCCc1nnc2ccccn12)c1cc2c(s1)CCCC2 +COc1ccccc1CNC(=O)CCNC(C)=O +CCN(C(=O)c1ccc(S(C)=O)cc1)c1cc(C)cc(C)c1 +Cc1cc(OCC(=O)N2CCCC(c3nc(C(C)C)cs3)C2)no1 +CN(C)S(=O)(=O)c1ccc(CNC(=O)Nc2cnn(C)c2)cc1 +COc1c(NC(=O)Nc2ccc3c(c2)oc(=O)n3C)c(C)nn1C +CC(NC(=O)C1CC(=O)N(c2ccc3c(c2)OCO3)C1)C1CCCO1 +O=C(Cc1ccc[nH]1)Nc1ccccc1OC(F)F +CN(C)C(=O)N1CCC(Nc2cccc(Oc3ccccn3)c2)CC1 +COc1ccc(C(=O)NC(C(=O)Nc2nccs2)C(C)C)cc1 +CC(=O)NC(C)(C)C(=O)N(C)Cc1ccc(C)s1 +COc1cc(C)c(C(=O)NCC(=O)NC2CCCCC2)cc1OC +CC(C(=O)Nc1nc(-c2ccco2)cs1)c1ccsc1 +N#Cc1csc(CN2CCn3c(nnc3C(F)(F)F)C2)c1 +CN(C)c1nc(Cn2ccc(-c3ccc(F)cc3)n2)ns1 +CC(Sc1nncs1)C(=O)Nc1c[nH]ccc1=O +CC(=O)Nc1cccc(C(O)CN2CCN(C(C)=O)CC2)c1 +Cc1nc(-n2cccc2)sc1C(=O)NC1CCCCC1C +CC(NC(=O)Cc1ccc[nH]1)c1ccc(OC(F)F)cc1 +NC(=O)NCCC(=O)NCc1ccc(N2CCCCC2=O)cc1 +CSc1ccc(C)c(C(=O)NCC2(C(N)=O)CCOCC2)c1 +O=C(CCSc1nnc2ccccn12)NCCc1ccccc1 +Cc1ccc(NC(=O)Cn2nnc3ccccc3c2=O)c(C)c1 +NS(=O)(=O)c1cc(C(=O)Nc2ccc(F)c(F)c2)ccc1Cl +COC(=O)C1CN(C(=O)Cc2ccccc2F)c2ccccc2O1 +Cn1cc(NC(=O)c2occc2COc2ccccc2)cn1 +CCc1onc(C)c1NC(=O)c1ccc2c(c1)ncn2C +CCOC(=O)C1CCN(S(=O)(=O)c2ccccc2Cl)CC1 +COc1ccc(CCNS(=O)(=O)Cc2ccccc2F)cc1 +Cc1ccc2c(CCNC(=O)c3nc4nccc(C)n4n3)c[nH]c2c1 +CC(C)n1ncc2c(C(=O)N3CCCCC3)cc(-c3ccco3)nc21 +COc1ccc(C2CCCN2C(=O)CCNC(N)=O)cc1 +COC(=O)C1CCCN(C(=O)c2nccc3ccc(N)cc23)C1 +Cc1c(Cl)cccc1NC(=O)CCNc1cn[nH]c(=O)c1Cl +CCCNC(=O)CN1C(=O)CNc2cc(C)ccc21 +COCCn1cnnc1S(=O)(=O)Cc1cc(C)ccc1C +CSc1ccc(C(=O)N(CC(C)C)CC(F)(F)F)cc1 +CCC(C)NC(=O)COc1ncnc2onc(-c3ccc(F)cc3)c12 +CCOc1ccc(-c2nc3sc(=Cc4ccco4)c(=O)n3n2)cc1 +CCOc1ccc(C(=O)Nc2c(C)cc(C)cc2C)cc1OCC +C=CCNc1oc(COc2ccc(OC)cc2)nc1C#N +COc1ccccc1S(=O)(=O)Nc1cccc(-c2nc[nH]n2)c1 +CCOCc1nc(-c2ccc(Cn3nc(C)cc3C)cc2)n(CC)n1 +Cc1c(Cl)cccc1-c1ccc(CNc2nc[nH]n2)o1 +Cc1cccc(NC(=O)CNC(=O)c2ccccc2F)n1 +COc1cccc(C(=O)N2CCN(CCC#N)CC2)c1 +c1cc(C2CCCC2)nc(N2CCCOC(CN3CCOCC3)C2)n1 +CC1CCN(C(=O)c2cccc(OC(F)F)c2)CC1 +COc1cc(C(=O)Nc2cccccc2=O)cc(OC)c1OC +COC(=O)c1ccc(NC(=O)CCC(=O)c2ccc(C)cc2)cc1 +CC(=O)OCC(CO)OCn1cnc2c(=O)[nH]c(N)nc21 +Cc1nc(CN2CCN(Cc3sc(N(C)C)nc3C)CC2)no1 +COCC(C)Nc1nc(-c2cccnc2)nc2ccccc12 +CCc1c(C(=O)Nc2cnn(C)c2)cnn1-c1ccc(C)cc1 +CC(C#N)(NC(=O)CN1CCCc2cc(F)cc(F)c21)C1CC1 +COc1ccccc1CCNC(=O)c1nc(-c2cnccn2)no1 +CCOc1ccc(C(=O)N2CCNC(=O)C2)cc1Br +Cc1cc2c(=O)n(CC(=O)NCc3cccc(Cl)c3)ccc2s1 +CN(Cc1nc2cc(C(F)(F)F)ccc2c(=O)[nH]1)c1ccccc1 +CCc1nc(C)c(C(C)OC(=O)Cc2c(C)nn(C)c2C)s1 +CN(Cc1ccccc1)C(=O)c1cnc(C(C)(C)C)nc1N +CCCc1nnc(NC(=O)NCc2ccnc(OC(C)(C)C)c2)s1 +CNC(=O)C1CCCN(C(=O)CSc2ccccc2)C1 +CCOc1c(Cl)cc(CN2CCOC3(CCC3)C2)cc1OC +CC1CN(C(=O)COc2ccc(F)cc2)CCO1 +Cc1cc(C(=O)N2CCCC(n3cccn3)C2)ccc1-n1cnnn1 +CCc1nnc(C(C)N(C)Cc2ccc(C(F)(F)F)cc2)o1 +Cc1ccc(C)c(S(=O)(=O)Nc2ccc(=O)n(C)c2)c1 +CC(C)Cn1c(=O)oc(=O)c2cc(Cl)ccc21 +Cc1ccc(NCc2nnc(C(C)(C)C)o2)c(C)c1 +CCOc1cc(CNc2ccon2)cc(Cl)c1O +COc1c(C)cnc(CSc2nnnn2C2CCOCC2)c1C +CCc1cc(NCC(O)COC2CCCCC2)n2nccc2n1 +CN(C)C(=O)c1ccc(CNC(=O)c2cnn[nH]2)cc1 +CC(C)Oc1ccccc1C(=O)Nc1ccn(Cc2cccnc2)n1 +CC(=O)c1ccc(F)c(S(=O)(=O)NC2CCCC2)c1 +CCSc1ccccc1C(=O)NCCCOC +Cn1c(=O)oc2ccc(NC(=O)c3ccc(C(F)(F)F)cc3)cc21 +CC(=O)NC1CCN(C(=O)c2cccc3c2OCO3)CC1 +COc1ccc(NC(C)C(=O)Nc2ccc(Cl)cn2)cn1 +CCNc1ccc(S(=O)(=O)N(CC)CC)cc1 +CC1(CO)CC2C(O)C(=O)C3(CO)CC3(C)C2C1 +COc1cc(CC(C#N)C(=O)NCC(C)C)ccc1O +CCC(C)Oc1ccccc1-c1ccc(C(=O)NC)c(N)n1 +O=C(NCCc1cccc(Cl)c1)NCc1ccco1 +Cc1ccc(C2CN(CC3CCCO3)CCO2)c(C)c1 +CCOc1ccc2c(c1)C(c1ccc(O)cc1)NCC2 +CC(C)(C)CC1CCCN1C(=O)Cc1csc(-c2nc[nH]n2)n1 +O=C(CCc1ccccc1Cl)N1CCCCC1CCO +Cc1nc(S(=O)(=O)CCCC#N)[nH]c1Cc1ccccc1 +O=C(Nc1cc(Cl)ccc1C(F)(F)F)c1ccncc1 +CC(=O)c1cccc(OC(C)C(=O)NCc2ccccc2)c1 +CS(=O)(=O)c1nccn1CCCC1CCCC1 +O=C(Cn1cncn1)Nc1ccc(F)cc1-c1ccc(Cl)cc1 +CCn1cnc(NC(=O)N(C)CC2Cc3ccccc3O2)n1 +CCN(Cc1ccncc1)C(=O)c1cnc2ccoc2c1 +Cc1ccc(NC(=O)c2ccc(N)cc2Cl)cc1F +N#Cc1ccccc1NC(=O)Cc1ccc(Cl)cc1 +CN1CC(NC(=O)COc2ccc(Br)cc2)CCC1=O +Cc1cccc(C)c1NC(=O)Cc1nc2ccccc2c(=O)[nH]1 +COc1cccc(OCCN(C)C(=O)CN2CCOC2=O)c1 +CC(NC(=O)N1CCCCC1c1cn[nH]c1)C(=O)N1CCCCC1 +COc1cc2c(c(Cl)c1OC)C(CC1CC1)NCC2 +COc1ccc(CNC(=O)c2ccc(-c3cccnc3)nc2)cc1OC +CCOC(=O)C(O)c1cc(C)c(Cl)cc1OC +CCCCOc1ccc(C(=O)NCC(=O)N2CCCCCC2)cc1 +COC(=O)C(N)c1cc(Cl)c2c(c1)OCCCO2 +O=C(C1CCCCC1)N1CC2CCN(c3ncccn3)CC2C1 +CC(=O)Nc1cccc2c1ccn2CC(=O)NCCC(C)C +CCN1CCc2cc(-c3cncn3CCCn3nc(C)cc3C)ccc21 +N#CCc1cccc(C(=O)N2CCCN(C(=O)c3ccccc3)CC2)c1 +COC(=O)CCNC(=O)c1ccccc1Sc1ccccc1C#N +O=C(NCc1ccon1)Nc1ccc(F)c(-n2cccc2)c1 +N#Cc1ccc(OC(=O)c2ccc(N3CCOCC3)nc2)cc1 +Cc1sc(=O)n(CC(=O)NCc2ccc(C#N)cc2)c1C +COc1ccc(CNC(=O)NCc2ccco2)cc1O +CC(Sc1nnnn1-c1ccc(O)cc1)C(=O)N1CCOCC1 +Cc1cc(C)c(C(=O)N2CCCC(Cc3noc(C)n3)C2)c(C)c1 +Cc1ccccc1N1CCN(C(=O)C2CCC2)CC1 +NC(=O)C1CCN(S(=O)(=O)C2=Cc3ccccc3CC2)C1 +Cc1nn(CC(C)C)c(C)c1CC(=O)OCc1ccoc1C +CCC(C(=O)Nc1cc(C)ns1)N1CCCC1=O +COc1ccc(C(=O)Nc2ncc(C)s2)nn1 +OC(Cn1ccnc1-c1ccccn1)c1ccccc1F +COC1(C)CC(NC(=O)c2scnc2C2CC2)C1(C)C +COc1cccc(-c2nccc(C3CCCN3c3ncccn3)n2)c1 +C#CCOC(=O)c1nc(-c2cccs2)n(-c2cccc(F)c2)n1 +CNC(=O)c1ccc(NC(=O)CNc2cccc(C)c2C)cc1 +Cc1cc(O)ccc1-c1nnc(-c2nonc2N)o1 +CCc1nc(CC(=O)NCc2cc(Br)cs2)cs1 +CCOc1cc(C(O)C(O)c2ccc(O)c(OCC)c2)ccc1O +Cc1ccc(C(=O)N(Cc2cnc3ccccn23)C2CC2)cc1 +COC(=O)N1CCC(NC(=O)NC(C)c2ccc(Cl)cc2)CC1 +CCC(C)(C)C1CCc2c(sc(NC(=O)OC)c2C(N)=O)C1 +COCC(=O)Nc1cccc(CNc2nc3ccccc3o2)c1 +Cn1cc(CNC(=O)c2nnc3ccc(Cl)cc3n2)cn1 +COC(=O)c1sccc1NC(=O)c1ccccc1 +Cc1csc(NC(=O)N2CCCCCC2c2c(C)n[nH]c2C)n1 +CC(C)(NC(=O)COC(c1ccccc1)c1ccccc1)C(N)=O +Cc1nn(C)c(C)c1CNC(=O)c1c(C)nn(-c2ccccc2)c1C +O=C(NCCCN1CCCCCC1=O)c1cnccn1 +O=C(CC1CCCC1)Nc1cccc(C(=O)N2CCCC2)c1 +CC#CCSc1nnc(N2CCOCC2)n1-c1ccccc1C +CC(C)c1nc(N2CCCC2=O)sc1C(=O)Nc1ccc(F)cc1 +CC(NC(=O)c1ccco1)C(=O)Nc1c(C(C)C)cccc1C(C)C +O=C(Nc1cccc(C(F)(F)F)c1)c1[nH]nc2c1CCCC2 +O=C(CCSc1ccccn1)N1CCN(Cc2ccccc2)CC1 +Cc1ccn(C(C)(C)C(=O)Nc2cccc(C#N)c2)c(=O)c1 +CCCCCCNS(=O)(=O)c1ccc(C#N)cc1 +CN(C)c1cccc(C(=O)N(C)C2CCc3ccccc3C2)c1 +COCCN(CCC#N)C(=O)c1cc(N)cnc1C +CCOC(=O)c1c(C)nc2ccc(Br)cn12 +CCOC(=O)C1CCN(C(=O)CN(CC)c2ccc(F)cc2)CC1 +CC(O)CNC(=O)Nc1ccccc1N1CCCC1 +COc1cccc2sc(NC(=O)CNC(=O)c3cccs3)nc12 +Cn1ccnc1C(NC(=O)CN1CCCC1=O)c1ccccc1 +O=C(Cc1cccc(O)c1)NCCc1cc(F)cc(F)c1 +Cc1nnc(CNC(=O)c2cc(F)ccc2NC(=O)C2CC2C)n1C +CC12CC3CC(C)(C1)CC(OCCn1cnnc1)(C3)C2 +O=C(NCc1nc(C2CC2)no1)Nc1cccc(Cl)c1F +CCOCCCNc1oc(-c2cccnc2)nc1C#N +Cc1n[nH]c(C)c1CNCC(O)c1ccc(F)cc1F +CCCCN(C)C(=O)C(NC(=O)c1ccco1)C(C)C +COc1ccc(OCCN(C)C(=O)Cc2c(C)nc(C)[nH]c2=O)cc1 +C=CCNC(=O)c1ccc(-c2cnn(-c3ccc(C#N)cc3)c2)nc1 +CC(=O)Nc1ccc(NCC(=O)N(C)C(C)C)cc1 +CCOc1cncc(C(=O)Nc2ccccc2OCC)c1 +CCn1nc(C(=O)Nc2ccn(C)n2)c(=O)c2cc(Cl)ccc21 +Cc1cc(F)cc2c1CCNC2CNC(=O)c1ccccc1 +COc1ccc(-c2n[nH]c(-c3ccc(O)cc3)n2)cc1N +NC(=O)Nc1ccc(Oc2ccc(C(F)(F)F)cn2)c(F)c1 +COCC(=O)N1CCC(c2nc3ccccc3[nH]2)C1 +CN(CCOc1ccc(F)cc1)C(=O)NCc1cccc(C(N)=O)c1 +CC(=O)c1cc(CCCNC(=O)OC(C)(C)C)ncc1O +CCOC(=O)Nc1ccc(Br)cc1C#N +CC(C)C(=O)NCCNC(=O)c1cc(Cl)ccc1Cl +Cc1ccc(CN(C)C(=O)Cc2c(C)nc3ccccc3c2C)o1 +O=C(Nc1nccs1)c1cccn(Cc2cccc(F)c2)c1=O +COCC(C)OC(=O)Cc1nc2ccccc2c(=O)[nH]1 +Cc1ccc(CNC(=O)COc2ccccc2C#N)cc1 +Cc1nc(CN2CCCC(c3noc(C4CC4)n3)C2)cs1 +Cc1nscc1C(=O)Nc1nc(-c2cc(C(N)=O)co2)cs1 +Cc1ccc(-c2csc3nc(C)[nH]c(=O)c23)c(C)c1 +Cc1noc(C)c1CNC(=O)c1c[nH]c2ncccc12 +COc1ccc(-n2cc3cnnc(-c4ccccc4)c3n2)cc1 +Cc1n[nH]c(C(C)C)c1C(=O)NCc1noc(-c2ccsc2)n1 +CCc1ccc(C(NC(=O)C2COCCO2)C(C)C)cc1 +Cc1nn(C)c2ncc(NC(=O)N3CCC(C)CC3)cc12 +COc1ccc(CNc2ncc(C(F)(F)F)cc2Cl)cn1 +NC(=O)CC1CCN(C(=O)c2cc(-c3ccccc3Cl)[nH]n2)CC1 +COc1cccc(CNC(=O)Cc2c(C)nc(C)[nH]c2=O)c1 +CC(C)CNC(=O)NC(c1cccc(F)c1)c1nccn1C +O=C(Nc1ccc(N2CCCC2=O)cc1)c1ccc(F)c(F)c1 +COC(=O)c1cc(NC(=O)c2ccc3ccccc3n2)c(F)cc1F +N#Cc1cccc(CNC(=O)Nc2nccs2)c1 +Cc1cc(S(=O)(=O)NCc2ccccc2)ccc1Cl +Nc1cnn(CCOc2cccc(Br)c2)c1 +COc1ccc(C2Nc3ccccc3C(=O)N2CC(F)(F)F)cc1 +Cc1ccc(S(=O)(=O)N2CCCC3(CCCC(=O)N3C)C2)cc1 +COC(=O)c1ccc(OC(=O)C2CC2c2ccccc2)c(OC)c1 +CCCCn1nc(-c2ccc(C)o2)nc1C(C)CN1CCOCC1 +COC(=O)C1(N(C)C(=O)c2cc(F)ccc2F)CCCCC1 +CC(=O)Nc1nc(C(=O)Nc2ccc(F)cc2)cs1 +CCNc1nc(C)c(C(=O)N2CCC3(CCCNC3=O)C2)s1 +COc1cccc(-c2nnn(Cc3ccc(F)c4cccnc34)n2)c1 +Cn1cc(C(=O)Nc2ccc3sccc3c2)cn1 +CNC(=O)C1CCC(NC(=O)NC(c2ccccc2)C(C)C)CC1 +Oc1ccc2cc(CNc3cccnc3)ccc2c1 +CC1(C)CCC(CNC(=O)C2CC(=O)Nc3ccccc32)CC1 +NC(=O)c1cccc(Cn2ccc(-c3ccc(F)cc3)n2)c1 +CCOC(=O)Cn1ccc(-c2ccccc2)c(C#N)c1=O +CN(CCCNC(=O)NCc1ccncc1)c1ccccc1 +CCCNC(=O)CNC(=O)NC(c1ccccc1)c1ccco1 +CCOC(=O)CCCC(=O)c1cccc(Br)c1 +Cc1ccc2[nH]c(CN3CCN(S(N)(=O)=O)CC3)cc(=O)c2c1 +COC(=O)C(c1cc(OC)ccc1OC)C1CC1 +O=C(c1ccc(Cn2cc(Cl)cn2)cc1)N1CCCCCC1 +Cc1nc(-c2ccc(CNC(=O)c3sc(C)nc3C)o2)cs1 +COC(=O)c1csc(S(=O)(=O)Nc2[nH]nc(C)c2C)c1 +O=C(COc1ccc(Cl)cc1Cl)NCc1ccccn1 +Cc1cc(C(=O)N(C)Cc2csc(C)n2)on1 +CC(CNC(=O)Cn1c(=O)oc2ccccc21)Oc1ccccc1 +O=C(Nc1ccc(-c2cc[nH]n2)cc1)C1CCOC1 +Cc1nc2ccccc2n1Cc1nc(C2CCOC2)no1 +CCCOC(=O)c1ccc(NC(=O)c2ccon2)cc1 +Cc1cc(C)nc(NC(=O)CCc2ccccc2)c1 +COC(=O)c1cc(-c2cc(OC)ccc2OC)n[nH]1 +Cc1cccc(C)c1NCC(=O)NC(C)c1ccc2c(c1)OCCO2 +CC(NC(=O)C(C)S(=O)(=O)c1nccn1C)c1ccc(F)cc1 +CC(=O)c1ccccc1OCC(=O)Nc1cc(C)cc(C)c1 +Cc1cc(C)n(CC(O)COc2ccc(Cl)cc2Cl)n1 +CC(NC(=O)c1ccc(C#N)cc1F)c1ccccc1 +O=C(Nc1c[nH]cc(Br)c1=O)c1cccc(Cl)c1 +Cc1cccc(C)c1OCC(=O)N1CCN(c2ccccc2O)CC1 +Cc1ccnc(Sc2ccc(S(N)(=O)=O)cc2N)n1 +CC(C)N(C(=O)COc1ccc(-c2nnco2)cc1)C(C)C +COc1cccc(C(N)=O)c1OCCc1ccc(F)c(F)c1 +O=C1CCC(C(=O)N2CCN(C(=O)c3ccco3)CC2)N1 +Cc1cc(C)cc(N2CCN(Cc3cccc4nonc34)CC2=O)c1 +Fc1cccc(-c2cnnc(N3CCCCCC3)n2)c1 +N#Cc1cccc(NC(=O)c2cccc(NC(=O)c3cccs3)c2)c1 +Cc1ccc(NC(=O)CN(C)C(=O)C2CCOCC2)cc1 +CC(O)(CNC(=O)NCc1ccnc(-n2ccnc2)c1)c1ccco1 +CCc1onc(C)c1NC(=O)C(C)(C)c1ccc(OC)cc1 +CC(C)n1cc(NCc2cc(F)cc3cccnc23)cn1 +CC(C)c1cc(C(=O)NCCCNS(C)(=O)=O)n[nH]1 +CC(NC(=O)Cn1ccc(=O)n(C)c1=O)C1CCCO1 +CCOC(=O)CSc1nc2ccccc2n1C(=O)OC +COc1ccc(-c2c(N)c(C(C)=O)c(C)n2C)cc1 +O=C(Nc1cc(N2CCOC2=O)ccc1F)C1CCC1 +CC1CCCCC1NC(=O)C(C)N1CCN(C(=O)CO)CC1 +Cc1ccc(CC(=O)Nc2c(C(N)=O)oc3ccccc23)s1 +COc1ccc(Cl)cc1NC(=O)c1ccc2[nH]nnc2c1 +CCn1nc(CC(C)C)cc1C(=O)N1CCNC(=O)C1CCO +COCc1cccc(S(=O)(=O)N=c2cccc(C)[nH]2)c1 +CCN(C(=O)c1cnc(C)cn1)c1cccc2ccccc12 +Cc1cc(NC(=O)Cn2ccccc2=O)n(Cc2ccccc2)n1 +CCOC(=O)CC(C)CNC(=O)c1cccc2[nH]ccc12 +CCC(C)C(=O)N1CCC(NC(=O)c2cccs2)CC1 +O=C(Cc1ccc2c(c1)OCCO2)NC1CCSc2ccccc21 +O=C(NCc1ccc(OC2CCCC2)nc1)c1ccc2cc[nH]c2c1 +COc1cc(C)c(S(=O)(=O)N(C)Cc2ccc(C)o2)cc1OC +CC(NC(=O)COc1ccc(Br)cc1)C1CC1 +CCN(Cc1ccccc1)C(=O)C(C)n1ccc2oc(C)cc2c1=O +Cc1nnnn1-c1ccccc1C(=O)NCc1ccccc1F +CC(C)(C)C(NC(=O)NCC(=O)N1CCCCC1)c1ccc(F)cc1 +COc1cccc(NC(=O)Cc2nc3ccc(C)cc3c(=O)[nH]2)c1 +CN(C)C(=O)Cc1nc(-c2ccc3c(c2)Cc2ccccc2-3)cs1 +COC(=O)c1cc(S(N)(=O)=O)ccc1NCC(C)C +O=C(NCCCn1cccn1)C1(c2ccc(F)cc2F)CCCC1 +N#CC1(NC(=O)CNc2ccc(F)cc2)CCCCC1 +COc1ccccc1CNC(=O)COc1ccc(C(C)=O)c(F)c1 +Cc1nc(CCNC(=O)COc2ccccc2Cl)cs1 +CC1CCCN(C(=O)Cn2cnc3sc4c(c3c2=O)CCCC4)C1 +COC(=O)c1sc(NC(=O)C2CCc3cn[nH]c3C2)nc1C1CC1 +CN(CC1CCCC1)C(=O)Nc1cccc(N2CCCC2=O)c1 +COc1ccc(Br)cc1-c1ncn[nH]1 +CCC(C)n1ncc(C(=O)Nc2cccc3[nH]cnc23)c1C1CC1 +COCCNC(=O)c1csc(-c2ccc(N3CCCC3)nc2)n1 +Cc1nc(CCNCc2cccc(OC(F)(F)F)c2)n[nH]1 +COc1ccccc1NC1CCN(c2ncccn2)CC1 +CC(=O)Nc1ccc(F)c(C(=O)N2CCOC(C)C2)c1 +CC(=O)NC(C(=O)N(C)Cc1cccc(Cl)c1)C(C)C +CCOC(=O)c1ccc(NC(=O)c2cn(C)nn2)cc1 +Cc1c(CCC(=O)Nc2nc3ccc(Cl)cn3n2)cnn1C +O=C(NC1CCCCNC1=O)c1ccc(-n2cccn2)cc1 +Cc1nccn1-c1cc(CNC(=O)C(C)n2cncn2)ccn1 +O=C(Nc1n[nH]c2ccccc12)C1CC(=O)N(Cc2ccco2)C1 +CNC(=O)c1c(NC(=O)c2c(F)cccc2F)sc2c1CCC2 +CC(=O)Nc1cccc(OC(=O)NC(C)(C)C)c1 +COC(C(=O)N1CCC(Nc2ccccc2)C1)c1ccccc1 +Cc1cc(C)nc(SCC(=O)NCCc2ccc(F)cc2F)n1 +CSc1ccccc1NC(=O)C1CCN(C(=O)NC2CC2)CC1 +C=CCn1c(SCC#N)nnc1C1Oc2ccccc2OC1C +CCC(=O)Nc1cccc(NCC(=O)N(C)Cc2ccccc2)c1 +O=C(CCn1nnc2ccccc2c1=O)Nc1nnc(C2CC2)s1 +CCOc1cccc(NCc2c(N)ncnc2OC)c1 +CCn1nnnc1NCc1cccc(OC)c1OC +Cc1c(C(=O)NCCc2nc(C(C)C)no2)oc2c(C)cccc12 +Cc1noc(C(C)OC(=O)C2CCCN2C(=O)Cc2ccccc2)n1 +COc1ccc(C(C#N)NC2CC2)cc1Br +Cc1cc(C2CC3CCC(C2)N3C(=O)C(C)O)ccc1F +CCN(CCO)C(=O)Nc1ccc(F)c(C(N)=O)c1 +CC(C)C(=O)NC1=NC(=O)C2=NCN(C3CC(O)C(CO)O3)C2=N1 +O=C(NCCc1cccc(F)c1)Nc1ccn(Cc2ccncc2)n1 +Cc1nc(CCNC(=O)c2cc(C(C)(C)C)nn2C)cs1 +CCCn1cc(C(=O)NCc2ccncc2)c2cccnc21 +O=C(Nc1cccc(C(=O)N2CCOCC2)c1)c1ccco1 +O=C(c1c[nH]cn1)N1CCOC(Cc2cccc(F)c2)C1 +CSc1nnnn1-c1cccc(NC(=O)C(C)c2cccs2)c1 +COc1ccccc1C(C)(C)NC(=O)NCCc1ncc(C)s1 +Cc1nc(N(CC(C)C)C(C)C)sc1C(C)O +CCCCNC(=O)c1c(N)oc2ccccc2c1=O +C#CCNS(=O)(=O)c1ccc(C(=O)OCC=C)cc1 +Cc1ccc(S(=O)(=O)CC(=O)Nc2ccc(F)cc2F)cc1 +COc1ccc(NC(=O)COc2ccc(F)c(F)c2)cc1 +CC(C)CCn1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)n1 +COc1ccc(N)cc1NC(=O)c1cc(Cl)c(OC)c(Cl)c1 +CC(=O)Nc1ccn(Cc2c(F)cccc2Cl)n1 +COC(=O)c1cccc(NC(=O)c2cnc(C)c(N)c2C)c1 +FC(F)(F)c1ccccc1-n1nc(C2CC2)c2c1CCNC2 +CN1CCCC2(CCN(C(=O)c3scc4c3OCCO4)C2)C1=O +COc1ccc(C)cc1CN(C)C(=O)c1cccc(-n2cccn2)n1 +CC(C)c1ccccc1NC(=O)COc1cccc2ccc(=O)[nH]c12 +CC(C)N(c1ccccc1)S(=O)(=O)c1ccc2c(c1)NC(=O)CO2 +CCc1cc(=O)[nH]c2cc(NC(=O)c3cnc4ccccc4n3)ccc12 +CCOc1ccc(-c2nc(CN)cc(=O)[nH]2)cc1OC +Cc1ccc(C)c(C(=O)Nc2cnc3c(c2)c(=O)n(C)c(=O)n3C)c1 +CSc1ncccc1C(=O)OCC(=O)c1ccc2c(c1)OCCO2 +Cc1cc(C)c2c(c1)C(O)C(N1CCC(=O)CC1)C(C)(C)O2 +C#CCn1c(CN(C)C(=O)c2ccco2)nc2ccccc21 +COCCCNC(=O)Cn1nc(-c2ccc(C)cc2)ccc1=O +CC(=O)Nc1cccc(S(=O)(=O)N(C)C2CC2)c1 +COCC(=O)Nc1nn2c(-c3ccc(F)cc3)nnc2s1 +COc1ccc(C2CCCN2C(=O)c2cnc3[nH]nc(C)c3c2)cc1 +CC(=O)c1cccc(NC(=O)c2ccc(-n3ccnc3)cc2)c1 +CC(=O)c1ccccc1C(=O)N1CCc2[nH]c(-c3ccccc3)nc2C1 +Cc1cc2c(cc1C(=O)NCc1ccc(Cl)cc1)OCCCO2 +Cc1cccc(CNC(=O)NC2CCN(CC(F)(F)F)C2)c1 +CCOc1ccc(C(=O)Nc2cccc(Br)c2)nn1 +CC(C(=O)NCC(C)(C)c1ccncc1)c1cccs1 +O=C(c1cc2cc(F)ccc2s1)N1CCCC(n2cccn2)C1 +CC1CN(S(=O)(=O)Nc2ccc(F)cc2F)CC(C)O1 +C#Cc1cccc(N(CC)C(=O)CNS(=O)(=O)c2cn(C)cn2)c1 +Nn1cc(-c2ccccc2)nc1SCC(=O)NCC1CCCO1 +CC(=O)c1cc(C(=O)NCc2cccc(Cl)c2C)[nH]n1 +N#Cc1cccc(CNS(=O)(=O)c2cccs2)c1 +COc1cccc(C(=O)CCC(=O)N2CCCCCC2)c1 +Cc1ccc(CN2C(=O)OCC2C(=O)NCCc2ccccc2)s1 +COC(=O)CCCNC(=O)c1sc2ccccc2c1Cl +NC(=O)NC(CC(=O)N1CCc2ccccc21)c1ccccc1F +CCN(CC1CC1)C(=O)c1cnc2[nH]nc(C)c2c1 +COCC(C)(O)CNC(=O)c1cccc(C(F)(F)F)c1 +CC(c1nccs1)N(C)Cc1cnc2c(-c3ccccc3)cnn2c1 +CCOC(CC)C(=O)Nc1cccc(CN(C)C(C)=O)c1 +NC(=O)CNC(=O)c1cccc(OC(=O)c2ccc3c(c2)CCO3)c1 +CC(c1ccccc1)N1CC(C(=O)NCC(N)=O)CC1=O +CC(C)(C)NC(=O)CSc1nccnc1Sc1ccccc1 +COc1cc2c(cc1F)CCNC2c1cccc(C)n1 +Cc1cc(C)n(CCCNc2ncnc3sc(C)c(C)c23)n1 +CNc1nc(-c2cccc(OC)c2)c(C)cc1C#N +CC1(C)CC(=O)c2sc(NC(=O)c3cnns3)nc2C1 +Cc1cc(Br)ccc1CC(=O)NCC(C)CC(C)O +Cc1nn(C)c(C)c1S(=O)(=O)N(CC1CCCCC1)C1CC1 +N#Cc1ccc(C(=O)NCCCCOc2ccc(F)cc2)cc1 +Cc1nn(Cc2cc(-c3ccccc3)on2)c(=O)c(C#N)c1C +COCc1ccc(C(=O)OCc2c(C)nn(-c3ccccc3)c2C)o1 +CCNC(=O)CN1CCN(C(=O)c2cc(CC)ccc2O)CC1 +CCCS(=O)(=O)NCc1ccc(S(=O)(=O)NC)cc1 +O=C(NCCc1nc(C2CC2)cc(C(F)(F)F)n1)c1ccsc1 +COc1ccc(NC(=O)COn2nnc3ccccc32)cc1 +c1cncc(CN2CCOC3CN(Cc4ccncc4)CCC3C2)c1 +O=C(c1ccc(C(F)(F)F)nc1)N1CCCC1C1CCCC1 +N#Cc1cccc2nc(Cc3ccc(F)cc3)nn12 +Cc1cc(NC(=O)c2cc3c(s2)CCCCC3)no1 +Cc1ccc2cccc(OCC(=O)c3cccn3C)c2n1 +O=C(NCc1cccnc1)c1csc2c1CCCO2 +CCc1c(C)nc(-n2nc(C)cc2C)n2c(=O)[nH]nc12 +O=C(NCc1ccco1)c1cnn(-c2ccc(Br)cc2)c1 +CCCN1CCN(C(=O)C2CCN(c3ccc(Cl)cc3)C2=O)CC1 +Cn1cccc1C(=O)N1CCC2C1CC(=O)N2c1ccsc1 +O=C(NC1CCCCC1)c1nc(N2CCOCC2)ncc1Cl +CCOc1ccc(Cl)c(C(=O)N2CCCC(c3cc(C)[nH]n3)C2)n1 +CC1CCc2sc(C(=O)N3CCCC(N4CCNC4=O)C3)cc2C1 +N#Cc1cccnc1N1CCC(OCCc2ccccc2)CC1 +Cc1cc2ncn(-c3nn(C)c(=O)n(C)c3=O)c2cc1C +CN(Cc1cccnc1)C(=O)c1ccc2c(c1)OCCO2 +COc1ccc(CCCC(=O)N2CCC(C)CC2)cc1N +Cc1ccc(Cl)cc1NC(=O)c1cccc(F)c1N +CCOc1ccccc1CNC(=O)N1CCOC(C)C1 +CCN1C(=O)C(C)(C(C)C)N(C)c2ccc(N)cc21 +CCCCN(C)C(=O)CNC(=O)c1cc(F)cc(F)c1 +CC(C)c1ccccc1NC(=O)Cn1cnc2c(cnn2C)c1=O +COc1cccc(F)c1C(C)NC(=O)NCc1ncn(C)n1 +O=C1OCCN1CCCn1c(C(F)(F)F)nc2ccccc21 +CC(Sc1ccccc1)C(=O)N1CCCn2nccc21 +Cc1csc(C2(NC(=O)c3cccc(F)c3)CCCC2)n1 +Cc1nccn1Cc1cccc(CNC(=O)c2ccc3cc[nH]c3c2)c1 +CC(CNC(=O)NCCN1c2ccccc2CC1C)N1CCOCC1 +CC(NC(=O)NCC(Cc1ccc(F)cc1)C(N)=O)c1ccncc1 +CSc1ccccc1C(=O)NCc1cccc(NC(=O)C2CC2)c1 +COc1cccc2c1OCC(CNc1ncc(F)c(N(C)C)n1)C2 +CCCc1cncnc1N1CCC(O)(C2CCOCC2)C(C)C1 +O=c1c2ccsc2ccn1CC(O)Cc1ccccc1 +CN1CC(C(=O)Nc2ccc(-n3ccnc3)cc2)CC1=O +CC(Cn1cccn1)NS(=O)(=O)N1CC(C)OC(C)C1 +COc1ccc2c(CC(=O)N(C)CC(=O)N(C)C)coc2c1 +Cc1nc(NC(C)(C)CO)c2cc(-c3ccccc3)sc2n1 +CC(c1cccc(Cl)c1)N(C)C(=O)COc1cccc(C(N)=O)c1 +Cc1noc(CNC(=O)Cn2c(=O)oc3ccccc32)n1 +O=C(NCc1ccco1)NCc1cccnc1OCc1ccccc1 +O=C(NCC(c1cccs1)N1CCCC1)C1Cc2ccccc2O1 +O=c1c2ccccc2ncn1Cc1nc(Cc2ccccc2)no1 +COc1ccc(-c2nc(C)c(C(=O)N3CCCCC3)s2)cc1OC +CCCC1CCC(NC(=O)c2ccc(-n3cncn3)nc2)CC1 +O=C(Cc1n[nH]c(=O)c2ccccc12)Nc1ccc2c(c1)OCO2 +Cc1cc(CN(C)C(=O)C2(c3ccccc3)CCC2)no1 +Cc1cc(N2CCC(c3nnc(C)o3)CC2)ncn1 +O=C(NCCN1CCOCC1)Nc1ccc2c(c1)OCCO2 +CCc1ccc(Cl)c(CC)c1NC(=O)c1cccc(NC(C)=O)c1 +O=c1c2ccsc2ncn1Cc1csc(-c2ccccc2)n1 +Cc1cc(C(=O)N=c2sc3cc4c(cc3n2C)OCCO4)nn1C +O=C(NCC(=O)N1CCOCC1)c1ccc(=O)[nH]c1 +COc1ccc(C2CC3(C)NC(=O)C2C(=O)N3)cc1 +Cc1cc(C)cc(S(=O)(=O)NCCCn2ncccc2=O)c1 +CC(C)CC(=O)NC1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +N#Cc1cccc(NC(=O)c2ccccc2OCC2CCCO2)c1 +COC(=O)C1CCN(C(=O)c2cccc(F)c2N)CC1 +COc1ccc(OC)c(-n2c(CCC(F)(F)F)n[nH]c2=O)c1 +CCN(CC(C)C)C(=O)c1cnc(C2CCCO2)s1 +COCCn1cc(NC(=O)NC(C)c2ccc(OC)c(F)c2)cn1 +Cc1ccc(NC(=O)C(C)NC(=O)CN2CCOC2=O)c(F)c1 +CCOc1ccc(CC(=O)Nc2nnc(-c3ccn(C)n3)o2)cc1 +CNC(=O)COC(=O)c1cn(C)nc1C(C)(C)C +CS(=O)c1cccc(NC(=O)C2(c3ccccc3)CCC2)c1 +COC(C(=O)Nc1cccc(Cl)c1F)c1ccccc1 +CN1CCOc2ccc(NS(=O)(=O)c3cccs3)cc2C1=O +CC(=O)NCc1ccc(S(=O)(=O)N(C)C)s1 +COc1cc(C)ccc1Oc1ccc(S(=O)(=O)N2CCCC2)cn1 +CCC(=O)N1CCCC(C(=O)Oc2ccc(C(C)=O)cc2)C1 +COc1ccc(NC(=O)N(C)CC(C)C)cc1C +Fc1ccccc1NCc1nc2n(n1)CCCCC2 +Cc1cc(Cn2nc(-c3ccccc3)cc(C(F)(F)F)c2=O)on1 +COc1ccc(F)c(NC(=O)NC2CCN(CC(F)(F)F)C2=O)c1 +Cn1nnnc1Sc1ccc(S(=O)(=O)N2CCCC2)cn1 +CC(C)CCN1C(Cl)=Nc2ccccc2S1(=O)=O +COC(=O)CN1C(=O)C(C)Oc2cccc(N)c21 +CCOc1ccc(NC(=O)N2CCOC(C(N)=O)C2)cc1C +Cc1nc2ccccc2nc1COC(=O)Cc1c(C)noc1C +CCOC(=O)CCC1NCCc2cc(F)c(F)cc21 +CCS(=O)(=O)NCC#Cc1cccc(Cl)c1 +Cc1nc2c(s1)C(OC(=O)CCc1c(C)nn(C)c1C)CCC2 +Cc1nc(-c2oc(C)nc2C)n(C2CCCCC2)n1 +CC1(C)Cc2cccc(Oc3cc(C#N)ccn3)c2O1 +Cc1cccc(N2CCN(S(=O)(=O)N(C)C)CC2)c1C +COc1cc(CO)ccc1OCC(=O)Nc1ccc(C)cc1 +OCc1c(-c2ccc(F)cc2)nc2ccc(Br)cn12 +CC(=O)Oc1cccc(NC(=O)Cc2ccc(Cl)cc2)c1 +CC(NCCN1CCOCC1)c1cccc(O)c1 +CCOC(=O)c1cnc(N(C)C)nc1C(F)(F)F +COc1cc(O)c2c(c1O)OC(c1ccccc1O)CC2=O +CC(=O)c1csc(NC(=O)c2ccc(-c3ccccc3)nc2C)n1 +CCCCN(C(=O)c1nc2nc(C)cc(C)n2n1)c1ccccc1 +COC(=O)c1ccccc1NC(=O)c1cn2ccccc2n1 +CCN(CCO)C(=O)c1cnn(-c2ccccc2)c1C +CN(Cc1ccc2c(c1)OCCO2)C(=O)c1cccs1 +O=C(c1cccs1)N1CCC(c2nnc3n2CCC3)CC1 +Cc1cccc(CC(=O)OCC(=O)NC2CCc3ccccc32)c1 +Cc1ccc(N2CCCC2=O)c(C(=O)NCCC(C)C)c1 +CC(C)OC(=O)CCC(=O)Nc1ccc(Cl)cc1 +COc1ccc(F)cc1NC(=O)c1cc(F)c(F)c(F)c1F +N#Cc1ccc(C(=O)N2CCC(OCc3ccc(F)cc3)CC2)nc1 +Clc1ccc2c(c1)C(c1nccs1)NCC2 +CC(=O)c1ccc(NC(=O)CCc2ccccc2)cc1 +Cc1nccn1-c1ccc(NC(=O)c2cccc3ccccc23)cn1 +Nc1c(-c2cccnc2)nc2ccc(Br)cn12 +Cc1cc(C)cc(NS(=O)(=O)N2CCCCC2)c1 +Cc1ccc(CN(C)C(=O)c2cc(-c3ccco3)nc3ccccc23)o1 +Cn1nnc(CO)c1COc1ccc(Cl)cc1Cl +CCOC(=O)CNC(=O)c1cc2ccccc2s1 +COc1ccc2c(c1)NC(C)C(=O)N2Cc1ccccc1C#N +CC(C)NC(=O)CNC(=O)c1cccc(-c2nnnn2C)c1 +CC(C)(C)c1cnc(CN2c3ccccc3CS2(=O)=O)o1 +COC(=O)C(CNC(=O)c1cc[nH]n1)Oc1ccc(F)cc1 +O=C(CSc1ccncc1)Oc1ccc(Cl)cc1 +CC1CN(C(=O)CCn2cncn2)CC(c2ccccc2)O1 +CN(Cc1ccccc1Cl)S(=O)(=O)CCCO +Cn1nc(C(F)(F)F)c(C#N)c1S(=O)(=O)c1ccccc1 +O=C(OCc1nnc(-c2ccccc2)o1)C1CC1(Cl)Cl +CCN(CC(=O)NC1CCCNC1=O)c1ccccc1 +COC(=O)c1ccc(F)c(S(=O)(=O)NC(C)c2cccnc2)c1 +Cc1cc(CN2CCN(C(=O)c3ccc(S(C)=O)cc3)CC2)on1 +COc1ccc(Cl)c2c1CCNC2c1cccnc1F +CC(CCO)NC(=O)NC1CCCN(Cc2ccccc2)C1=O +CC(=O)NCc1ccc(-c2csc(NC(=O)C3CC3)n2)cc1 +COc1cccc(OCC(=O)Nc2ccc(C)cc2F)c1 +Cc1cc(C)n2nc(SCc3noc(-c4ccsc4)n3)nc2n1 +Cc1csc(NC(=O)c2cc3sccc3n2C)n1 +O=C(Nc1ccc(F)cc1Cl)c1ccc(-n2ccnn2)cc1 +CC(C)CCNC(=O)C(C)Oc1ccc(C#N)cc1 +COc1cc(C)c(CNc2ccc(F)c(NC(C)=O)c2)cc1OC +Cn1c(=O)oc2cc(NC(=O)NCC(C)(C)c3ccccc3)ccc21 +Cc1ccc(-c2nc(CCNc3ccc(C(N)=O)nn3)cs2)cc1 +O=S(=O)(c1ccc(Cl)cc1F)N1CCOCC1C1CC1 +CC(=O)c1ccccc1OCCCCN1CCOCC1 +CC1C(=O)Nc2c(Cl)cc(C(O)C3CCCCC3)cc21 +COc1ccc(C(C#N)NC(=O)Cc2cccs2)cc1 +COc1ncccc1CNC(=O)NCc1ccccc1C +CCOCCCNC(=O)c1cc2cc3cc(OC)ccc3nc2o1 +COc1cc(C)cc(OC)c1OCc1cc(C)on1 +Cc1cc(Br)c2c(c1)C(O)(N1CCC(C)CC1)C(=O)N2 +Cc1cc(C)n(-c2ccc(C(=O)NCCC(=O)N3CCCC3)cc2)n1 +CC(=O)N(Cc1ncc(C)o1)C1CCN(CC(C#N)CCC#N)C1 +CCOc1c(OC)cc(C2NC(=O)c3ccccc3N2)cc1OC +C#CCOc1ccc(C(=O)NCCc2nc(N)no2)cc1 +Cc1[nH]ncc1CCCNC(=O)NCCc1ccccc1F +Cc1ccc(Cl)c2sc(NC(=O)c3ccn(C)n3)nc12 +CCC(C(=O)Nc1cccc(N)c1)n1ccccc1=O +CCC(C)NC(=O)COc1ccc(OC)cc1CO +O=C(CSc1ccc(F)cc1)Nc1ccc(Br)cn1 +CCc1noc(CC)c1CNC(=O)Cc1csc(C)n1 +COc1cc(NC(=O)N(C)Cc2cc(C)on2)cc(OC)c1 +O=C1Cc2cc(NC(=O)c3cccc(Oc4ccncc4)c3)ccc2N1 +Cn1nc2n(c1=O)CCN(Cc1ccc(C#N)cc1)C2 +Cc1ccc(N)c(NC(=O)Cc2cccs2)c1C +O=C(Cc1ccc(Cl)cc1Cl)NCCc1nnc2ccccn12 +COC1CCCC1OC(=O)c1cn(-c2ccccc2)nc1C +O=C(COc1ccc(Cl)cc1)Nc1noc2ncccc12 +CC(=O)c1cccc(NC(=O)Cn2c(=O)oc3ccc(Cl)cc32)c1 +CCCc1nc(SC2CCCC2)c2c(=O)n(C)c(=O)n(C)c2n1 +Cc1ccc(-c2nnn(CC(=O)NCCc3ccccn3)n2)cc1 +CC1(NC(=O)CCCc2ccc3c(c2)CC(=O)N3)Cc2ccccc2C1 +CC(C)OCCC(=O)N1CCC(C(=O)N(C)C(C)C)CC1 +Cn1cccc1C1CCCN1Cc1cc(=O)n(C)c(=O)n1C +COc1ccccc1-c1c2c(=O)n(C(C)C)ccc2nc2ncnn12 +COCc1nc(NCCn2cccc2)c2cnn(C)c2n1 +CC(=O)NS(=O)(=O)c1ccc(NC(=O)c2cccc(F)c2)cc1 +Cc1ccc(CC(=O)Nc2ccc(Cl)cc2F)cn1 +C=CCCCN(C)C(=O)c1cc2ccccc2c(=O)[nH]1 +Cc1ccc(CNC(=O)NCCc2nc(C(C)C)no2)cc1 +CCOCC12COCC1CN(C(=O)CCc1ccccc1)C2 +CCOC(=O)c1sc2ncnc(Sc3nc(C)c(C)o3)c2c1C +O=C(COCc1nc(-c2ccncc2)no1)NCc1cccc(F)c1 +O=C(c1nnc(Cc2cccc(Cl)c2)o1)N1CCOCC1 +N#CC(CC(=O)N1CCCCCC1)c1ccc2c(c1)OCO2 +CNC(=O)c1ccc(CN2CCCn3nc(C)cc32)cc1 +Cn1nccc1C(=O)NCc1cccnc1Oc1ccccc1 +O=C1CC2C(CCN2C(=O)c2ccccn2)N1Cc1cccnc1 +COC(=O)C1CCCN1Cc1cccc(C(=O)NCC(C)C)c1 +Cc1cc(C(=O)N2CCN(C(=O)C3CCCO3)CC2)c(C)n1C1CC1 +CCCc1nnc(NC(=O)CC(C)c2ccccc2)s1 +N#Cc1ccc(-c2ccccn2)n(CCCO)c1=O +Nc1c(-c2ccc(F)cc2)nnn1-c1ccc(Cl)cc1 +CC1C(=O)NCCN1C(=O)COc1ccc(Cl)cc1 +O=C(NCc1cccnc1-n1cncn1)c1ccncc1 +CCn1nc(C)c(CCC(=O)N2CCCCC2)c1C +Cc1n[nH]c(C)c1NC(=O)c1c(F)cc(OC(F)F)cc1F +Nc1cc(S(=O)(=O)NC2CCCC2)ccc1Cl +CC(C)C(=O)N1CCCC1C(=O)Oc1ccccc1Cl +CCN(CCC#N)C(=O)COc1ccccc1C#N +N#Cc1cc(-c2cccs2)nc(N2CCCC2)n1 +Cc1cnc(C(=O)Nc2cccc(C(=O)NC(C)(C)C)c2)cn1 +Cc1cc(NS(=O)(=O)c2ccc(N)cc2)ccc1Br +Nc1cncc(S(=O)(=O)NCc2ccc(Cl)cc2)c1 +Cn1ccnc1COC(=O)c1ccc(-n2cnc3ccccc32)nc1 +COC(=O)CCSc1nnc(-c2ccccc2OC)o1 +O=C(Cc1cccs1)NCCn1nc(-c2ccco2)ccc1=O +CCOC(=O)c1cc(S(=O)(=O)Nc2ccc(F)cc2C)cn1C +CC(c1ccc(-n2cncn2)cc1)N(C)C(=O)c1ccncc1 +CNc1nc(-c2cnn(-c3cccc(C)c3)c2C)cs1 +O=C(CSc1ccc(F)cc1)NCc1cc(-c2cccs2)on1 +CCc1nc2cc(N)ccc2n1CCC(=O)N(C)C +Cc1ccccc1Cc1nnc(Cn2cnc(-c3ccccc3)n2)o1 +COc1cc(S(=O)(=O)n2ccc(C)n2)ccc1F +Cc1ccn2cc(C(=O)N3CCCCC3Cn3cccn3)nc2c1 +Cc1c(C(=O)Nc2ccccc2OCC2CC2)cnn1-c1ccncc1 +CC(OC(=O)c1ccc(-c2cscn2)cc1)c1nccs1 +COc1nc(NC(=O)c2ccc(-c3cccs3)nc2C)n[nH]1 +O=C(NCCCO)NC1CCSc2ccc(F)cc21 +COCCN(Cc1cnc2cc(C)ccn12)CC(F)F +CCc1n[nH]c(=O)c(CNC(=O)c2ccc(F)cc2Cl)c1CC +COC(=O)NCC(=O)NC(c1cccs1)C1CCCC1 +CCCn1nccc1C(=O)Nc1cc(C)ccc1OC +COc1ccc(C(=O)N(C)C2Cc3ccccc3C2)cc1OC +Cc1ccccc1C(C#N)NC(=O)CCN1CCCC1=O +COC(=O)C(C)CNC(=O)Nc1c(C)cc(C)cc1C +O=C1C2CCCC1CC(C(=O)N1CCOC(c3ccc(F)cc3)C1)C2 +Cc1c(C(=O)N(C)C2CC2)cnn1-c1cccc(Cl)c1 +CC(=O)Nc1ccc(F)c(C(=O)N(C)CCOCc2ccccc2)c1 +Cc1ccc(C(=O)Nc2nc(-c3ccccc3)cs2)o1 +CCCCN(CC)S(=O)(=O)c1cccc(C(=O)N(C)C)c1 +O=C(Cc1csc(NC(=O)c2ccco2)n1)NCc1cscn1 +N#CC(C(=O)c1ccc(Cl)cc1)c1nc2ccccc2[nH]1 +CCn1ncc2c1CCCC2NC(C(=O)NC1CC1)c1ccccc1 +CCCn1nc(C(=O)Oc2cccc(C(=O)N(C)CC)c2)ccc1=O +N#Cc1ccc(S(=O)(=O)NCCCSc2ccccc2)cc1 +CC(C)(C)Oc1cc(CNC(=O)N2CCCC(CC(N)=O)C2)ccn1 +Nc1cc(Cl)c(F)c(S(=O)(=O)NCCS(N)(=O)=O)c1 +O=C1CSc2ccc(NC(=O)Nc3ccccc3Cl)cc2N1 +CC(C)(C)C(=O)N1CCN(C(=O)c2cn3cccnc3n2)CC1 +Cc1occc1C(=O)N1CCCCC1CCN1CCOCC1 +CCc1ccc(C(=O)N(C)CC(C)C(=O)OC)cc1 +CCn1nnnc1-c1cccc(C(=O)Nc2ccc(C(C)=O)cc2)c1 +CCN(C(=O)CSc1nc2ccccc2o1)C1CC1 +CCc1cc(C(=O)Nc2cc(OC)ccc2OC)cs1 +CC(=O)c1ccccc1NC(=O)c1cc2c(cc1Cl)OCCO2 +CS(=O)(=O)N1CCC(OC(=O)Cc2c(F)cccc2F)CC1 +CCc1cccc(CC)c1NC(=O)C(C)Sc1nnc(CC)n1N +CCNC(=O)CNC(=O)NCC(C)c1nc(-c2ccccc2)no1 +Cc1nn(C)c(C)c1C(=O)Nc1cccc(Cl)c1Cl +CCOc1ccc(F)c(C(=O)NCC2CCCO2)c1F +O=C(Cn1sc2ccccc2c1=O)N1CCCC2(CCCO2)CC1 +CNc1snc(C)c1C(=O)NC1CCCC(C)C1 +Cn1ccnc1SCC(=O)NCc1ccco1 +COCC(=O)N1CCN(C(=O)Nc2cc(Cl)ccc2Cl)CC1 +CNC(=O)NCC(=O)NCCc1ccc(F)c(Br)c1 +O=C(CSc1n[nH]c(=O)[nH]c1=O)NCc1ccc(Cl)cc1 +O=C(Nc1ccccc1-n1cncn1)c1cc2ccccc2c(=O)[nH]1 +Oc1cc(F)c2c(c1)C(Cc1ccccc1O)NCC2 +OCc1cccn1-c1ncc(C(F)(F)F)cc1Cl +CC(C)(C)N(Cc1ccc2c(c1)OCCO2)C(=O)c1ccco1 +Cn1ncc(C(=O)NCC(=O)Nc2cccnc2)c1-c1ccccc1 +Cn1c(-c2ccc(NC(=O)c3cn[nH]n3)cc2)nc2ccccc21 +CN(CCOCC1CC1)C(=O)c1cc(C2CC2)nc2c1c(=O)[nH]n2C +Cc1nc(N2CCN(Cc3cccnc3C)CC2)c2cnn(C)c2n1 +O=c1ccn(-c2cccc(F)c2)nc1-c1nc(-c2ccccc2)no1 +Cc1nn(Cc2noc(C3CCCCC3)n2)c(C)c1CCO +Cc1cc(C(=O)Nc2ccc(S(N)(=O)=O)cc2F)on1 +Cn1ccnc1C(CCc1ccccc1)OC(=O)C1CCCOC1 +CC(C)C(=O)Nc1cc(N2CCN(Cc3ccccc3)CC2)ncn1 +Cc1cccc(-c2cnc3c(Br)cnn3c2)n1 +CCn1c(C(=O)N2CCC(C(N)=O)CC2)cc2sccc21 +CCC(NC(=O)CC(C)c1cccc(OC)c1)c1nc(C)n[nH]1 +COc1ccc(C2CCCN2C(=O)C(C)n2ccnc2)cc1 +Fc1ccc(CN2CC(c3nc(-c4cnccn4)no3)C2)c(F)c1 +CCCn1cc(C(=O)Cc2cc(C)cc(C)c2)cn1 +CCn1nc(C)c(Cl)c1C(=O)Nc1ccc(S(N)(=O)=O)cc1 +O=C(Cn1ccnc1-c1ccccc1)NCC(F)(F)F +Cc1ccc2nc(CN(C)c3nc4c(s3)c(C)nn4C)[nH]c2c1 +Cn1c(CSc2ncc(-c3ccc(F)cc3)[nH]2)cc(=O)n(C)c1=O +Nc1ccc(C(=O)N2CCCc3ccccc32)nn1 +COCC(C)NS(=O)(=O)c1cc(C)ccc1OC +C=CCNC(=O)Nc1ccccc1CC(=O)N(C)C +Cc1ccc(C(C)NS(=O)(=O)c2cnn(C)c2)cc1 +Cc1ccccc1NC(=O)NCc1cnn2ccccc12 +CCCOc1cccc2c1C(c1ncccn1)NCC2 +COc1ccc(CNC(=O)C2CCC(=O)N2C(C)C)c(OC)c1 +COc1ccc(NC(=O)c2cc(=O)c3ccc(C)cc3o2)cc1 +CC(=O)Nc1nc2c(s1)CN(C(=O)c1cccnc1)CC2 +O=C(CCc1ccco1)NCC(=O)NCC1CCCC1 +CCCCn1nc(C(=O)Nc2cc(F)c(OC)cc2OC)ccc1=O +Cc1nn2cc(C(=O)NCc3ccc(C(F)(F)F)cc3)nc2s1 +CC(C)CC(C)OC(=O)c1ccc2c(c1)OCC(=O)N2 +Cc1nc(C)c2c(C)c(C(=O)Nc3nnc(C)s3)sc2n1 +CCn1nc(C)c(CNC(=O)Nc2cc(C)cc(C)c2)c1C +Cn1c(N2CCCC2Cn2cncn2)c(C#N)c(=O)n(C)c1=O +CC(=O)NCC1CCCN(c2ncnc3[nH]cnc23)C1 +CCCn1nccc1C(=O)Nc1nc2ccccc2s1 +Cc1cc(C)c(CCNC(=O)C2CC(=O)N(C)C2)c(C)c1 +Cc1nc2c(C#N)cnn2c(C)c1CCC(=O)NC(C)C1CC1 +CCN(CC)C(=O)CN(C)c1ccc(Br)cn1 +Cc1cccc(NC(=O)CCc2ccc3c(c2)OCO3)n1 +CCn1nccc1C(=O)Nc1nc2ccc(SC)cc2s1 +CCOc1ccccc1NC(=O)N(Cc1ccco1)C1CCOCC1 +Cc1c(C(=O)NC2CCCC(C3CC3)C2)cnn1-c1ccncc1 +O=C(NCC1CCOC1)c1ccc(-c2cnco2)cc1 +C#CCN1CCN(C(=O)C2CC2c2c(F)cccc2Cl)CC1 +CC1CCC(NC(=O)CCCCC(=O)NC2CCC(C)CC2)CC1 +Cc1ccc(C)c(OCCc2cc(N)n(CCO)n2)c1 +O=C(NC1CCN(C2CCOC2=O)CC1)c1ccccc1 +COc1ccc(CNC(=O)Cc2ccc[nH]2)cc1NC(C)=O +O=C(NCCn1ccc(-c2ccncc2)n1)c1ccccc1Cl +COCCCSc1nnnn1-c1ccc(C)c(C)c1 +Cc1cc2c(cc1Br)CCNC2CC1CC1 +CCC(C)N(CC(=O)Nc1ncc(C)s1)C(=O)c1ccc(C)cc1 +CCOC(=O)CNS(=O)(=O)c1ccc(F)cc1Br +CCn1cc(CN2CCNC(=O)C2c2ccccc2C)cn1 +COc1ccc(-c2ccc(CNC(=O)Cn3cccn3)s2)cc1 +CCOc1ncccc1C(=O)Nc1nnc(SCC)s1 +O=C(NCCCN1CCCC1=O)c1nc(-c2cccs2)no1 +COC(=O)Nc1ccc(NC(=O)c2ccc(O)c(Cl)c2)cc1 +Cc1c(Cl)cccc1N1CCCn2c1nc1c2c(=O)[nH]c(=O)n1C +CCNC(=O)CNC(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +O=C(COC(=O)Cc1ccccc1F)NCc1ccccc1Cl +CCNC(=O)CNC(=O)c1ccc(Br)cn1 +CCc1ccc(C(=O)N(C)Cc2cc(OC)ccc2OC)cc1 +CCc1ccc(C(=O)N(C)Cc2nc3ccccc3s2)cc1 +Cc1cc(C)c(C(=O)NCCC(O)C(C)(C)C)c(C)c1 +Cn1cc(CN2CC(n3cccn3)C3OCCCC32)cn1 +COc1cc(CNC(=O)C2CCOC2)cc(OC)c1 +CC(C#N)N1CCN(c2cc(Cl)ccc2Cl)CC1 +CN(Cc1ccsc1)C(=O)Cc1cccs1 +CCOC(=O)C1CCC(NC(=O)c2cccc3[nH]ccc23)CC1 +CC(NC(=O)c1cccs1)C(=O)NCc1cc2ccccc2o1 +Cc1ccc(NC(=O)CSc2nc(C)cc(=O)[nH]2)cc1 +CN1CC(C(=O)Nc2ccc(F)cc2OCC2CC2)CC1=O +CCNC(=O)CCc1[nH]c(C)c(C(=O)OCC)c1C +O=C1NC2(CCCN(C(=O)C3CCC3)C2)N=C1c1ccccc1 +O=C(NC1(c2ccc(Cl)cc2)CCC1)C1CCOC1 +CC(C)Oc1ccc(C#N)cc1NC(=O)NCCC(=O)N1CCCC1 +Cc1ccc(-n2c(=O)n(C)c3ccccc32)cc1N +Cc1cc(NC(=O)COC(=O)Cn2ccc(C(F)(F)F)n2)no1 +CN(C)c1ccnc(C(=O)Nc2c(F)cccc2NC2CC2)c1 +Cc1ccc(CNC(=O)c2nnn(Cc3cccc(F)c3)c2N)cc1 +COc1cccc(-c2n[nH]c3c2C(c2ccc(O)cc2)NC3=O)c1 +c1cc2c(cc1-c1ccc(SCCC3OCCO3)nn1)OCO2 +N#Cc1ccc(NCc2ccc(S(N)(=O)=O)s2)nc1 +O=C(NCC1CCCC1)Nc1nnc(C2CC2)s1 +COc1ccc2[nH]c(C(=O)Nc3ccc(F)cc3)cc2c1 +CNC(=O)c1cccc(Cn2nnc(-c3ccc(C(N)=O)cc3)n2)c1 +CC(C)(C)OC(=O)N1CC(c2ccc(F)cn2)C1 +CCOc1ccc(NC(=O)N2CCOCC2)cc1F +O=C(Cc1c[nH]c2ccccc12)OCC(=O)c1ccccc1 +O=C(CCCc1ccccc1)Nc1ccc(-n2cnnn2)cc1 +COc1ccc2c(c1)OCC(NC(C)c1cccc(NC(C)=O)c1)C2 +COCC(=O)Nc1ccc(Nc2nccc(OC)n2)cc1 +O=C1CCC(C(=O)N2CCCC(COCc3ccccc3)C2)N1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ccc(C)cc2Cl)c1C +CC(NC(=O)Nc1ccccc1CC(N)=O)c1cccs1 +CCOC(=O)CCc1cc2c(cc1OC(C)=O)nnn2C(C)=O +Cc1c(N)cccc1-c1nn2c(=O)c(Cc3ccco3)nnc2s1 +Cc1csc(CNC(=O)N2CCN(c3ccccc3F)CC2)n1 +CC(C)CNC(=O)NC(C)c1nnc2ccccn12 +COc1ccc(CCNC(=O)C23CCC(C2)C(C)(C)C3=O)cc1OC +CC(=O)Nc1ccc(NC(=O)c2csnn2)cc1 +CCn1c(=O)c(NCc2cc(F)cc(F)c2)nc2ccncc21 +COc1cc(N)c(NC(=O)CCc2ccccc2)cc1OC +CN(C)c1ccc(C#CCNC(=O)c2cc(C3CC3)on2)cc1 +CCCC1CCC(NC(=O)c2nc3nc(C)cc(C)n3n2)CC1 +CC(c1nc(-c2ccc(Cl)cc2)no1)N1CCN(CC(N)=O)CC1 +CC(=O)N1CCCC(NCc2ccc(F)cc2)C1c1ccc(C)s1 +CC(=O)c1ccc(NC(=O)c2ccc(-c3n[nH]c(C)n3)cc2)cc1C +Cn1ncc2c1CCCC2NC(=O)c1ccc(S(C)(=O)=O)cc1 +COCc1ncsc1-c1nnc(NCC(C)C)s1 +COCc1ccc(C(=O)NCc2ncccc2C)o1 +CCn1nnnc1COc1ccc(C(=O)NCc2cccnc2)cc1 +CCN(CCO)C(=O)C1CSc2nc(C(C)(C)C)cc(=O)n2C1 +COc1ccc2oc(C(=O)NCC(N)=O)c(C)c2c1 +Cn1ccnc1S(=O)(=O)Cc1ccccc1F +Cc1ccnc(CC(C)N(C)C(=O)c2cnn3ccccc23)c1 +CC1CCN(C(=O)CNC(=O)C2CC2)c2ccccc21 +COc1cccc2cc(C(=O)N(C)CC(=O)N(C)C)oc12 +O=C(NCc1ccsc1)Nc1cnn(-c2ncccn2)c1 +O=C(Nc1ccc(N2CCCCC2)nc1)C1CCCO1 +CCOCCCC(=O)Nc1ccc2ccccc2c1 +CN(Cc1ccccc1)S(=O)(=O)N1CCC(O)C1 +O=C(Cc1ccccc1Cl)Nc1nnc(Cc2ccccc2)o1 +COc1ccc(NC(=O)NCc2n[nH]c(=O)c3ccccc23)cc1 +CCN(CC)C(=O)C(C)Nc1cccc(OC)c1 +NC(=O)c1ccc(C(=O)OCC2CCCCO2)cc1 +CS(=O)(=O)c1ccc(C(=O)NCCCn2cccn2)cc1 +CCCc1nnnn1Cc1ncn(-c2ccccc2)n1 +CCc1onc(C)c1NC(=O)NCC1C2Cc3ccccc3C12 +CN1CCN(C(=O)CNc2ncnc3sccc23)CC1 +Cc1cc(C)n(CCc2c(-c3ccccc3)ncn2C(C)C(N)=O)n1 +CCc1nc2n(n1)CCCC2NC(=O)Nc1ccc(Cl)cc1F +Cc1nnc(NC(=O)c2ccccc2N(C)c2ccccc2)s1 +Cn1c(C(=O)Nc2cnn(Cc3ccc(F)cc3)c2)cc2occc21 +CCOc1ccc(C(=O)Nc2ccc(F)cc2F)cc1OC +CCN(CC1CC1)C(=O)c1sc(C)cc1OC +COc1ncccc1C(=O)N(C)Cc1cc(C)on1 +COc1ccc(S(=O)(=O)Nc2ccc(C)cc2Cl)cc1OC +CCCNC(=O)COc1ccc(Br)cc1F +Cc1ccc(NC(=O)c2nnc3n2CCN(C)C3)cc1C +N#Cc1ccccc1Oc1ccccc1C(=O)N1CC(O)C1 +Cc1noc(C)c1CC(=O)N1CC(c2nc(-c3ccncc3)no2)C1 +CN(Cc1cccc(Cl)c1)Cc1cc(=O)n(C)c(=O)n1C +Cn1cc(C2CC2C(=O)N(Cc2ccsc2)c2ccccc2)cn1 +COc1ccccc1C(C#N)NC(=O)c1ccc(-n2ccnn2)cc1 +CCCC(C)(C)NS(=O)(=O)N1CCOCC1 +CC(CC(N)=O)NC(=O)CN1C(=O)CSc2ccccc21 +O=C(NCc1cn2ccsc2n1)N1CCCCCC1 +Nc1nc(CN2CCOCC2C2CC2)nc2sc3c(c12)CCCC3 +CC1CCN(C(=O)Nc2ccc3c(c2)OCC(=O)N3)CC1 +CCOCCCNC(=O)Cn1ncc2ccccc2c1=O +COC(=O)C1CCN(S(=O)(=O)c2cccc3cc(C)cnc23)CC1 +c1nc(N2CCCC2)ncc1-c1nc2cc3c(cc2[nH]1)OCCO3 +CCc1cc2c(SCC(=O)c3cc(C)n(C)c3C)ncnc2s1 +N#Cc1ccc(N2CCN(Cc3cccc(O)c3)CC2)nc1 +CCOCCn1c(CC)nc2cc(Cl)ccc21 +CC(C)COC(=O)CSc1nnc2c(n1)[nH]c1ccccc12 +CC(=O)Nc1ccc(OC(=O)C2CCCN2S(C)(=O)=O)cc1 +Cc1ccc(-c2cc(C(=O)N3CCOCC3c3ncon3)[nH]n2)cc1 +CC(CC#N)N(C)C(=O)Nc1ccc(F)c(Cl)c1 +Cc1cc(NC(=O)C(C)NC(=O)c2cccs2)n(C)n1 +CC(=O)Nc1ccc(-c2cc(CO)nn2CCCO)cc1 +O=C(c1ccccc1F)N1CCC(n2c(=O)oc3ccccc32)CC1 +CC(C)Cn1nccc1NC(=O)c1cc(C(C)(C)C)nn1C +Cc1ccc(NC(=O)Cn2ccccc2=O)c(F)c1 +Cc1ccc2nc(C)c(C(=O)N3CCN(CCO)CC3)cc2c1 +CCNC(=O)c1sc2nc(-c3ccccc3)cn2c1C +CCN(CC(=O)NC1CCCC1)S(=O)(=O)c1ccc(C)cc1 +Cc1cccc(OC(=O)COc2ccc3ccc(=O)oc3c2)c1 +CCCOc1ccc(OC)c(-c2cc(C(=O)OC)n(C)n2)c1 +O=C(NCCOc1ccc(Cl)cn1)c1ccnc(OC2CCC2)c1 +CCc1ccc(Nc2nnc(SCC(N)=O)s2)cc1 +O=C(NCc1cccc(F)c1)C1(c2ccc(F)cc2F)CCOCC1 +Nc1ccc(C2NCCc3cc(F)c(F)cc32)cc1 +Clc1ccnc(NCc2c[nH]c3ccccc23)c1 +CN1CCN(C(=O)c2nccc3ccc(N)cc23)CC1 +COC(=O)C1CC(O)CN1Cc1ccc(-c2ccccc2F)s1 +Cc1cccc(C)c1OCc1nnc2c(N)c(C)ccn12 +CCC(C)Oc1ccc(-c2cn[nH]c(=O)c2CC#N)cc1 +Cc1nc(=O)c(-c2ccccc2)c(C)n1CCN1CCOCC1 +O=C(NCCOCc1ccc(Cl)cc1Cl)C1CCOC1 +COCC12COCC1CN(C(=O)CC1=CCCCC1)C2 +COc1ccc(CN(C)C(=O)c2sc(C)cc2OC(F)F)cc1 +COCCOc1ncccc1C(=O)N1CCOC(C)(C)C1 +COc1ccc(S(=O)(=O)N2CCc3ncccc3C2)cc1 +O=C(NCC#Cc1ccc(N2CCOC2=O)cc1)c1ccccn1 +COc1ccccc1C(=O)CC(O)(c1nccn1C)C(F)(F)F +CNC(=O)c1c(C)nc(N)nc1-c1ccccc1OC(C)C +CCOc1ccc(F)c(C(=O)N(C(C)C)C(C)C)c1F +CC(C)c1nnc(C2CCN(C(=O)c3ccc4ccccc4c3)CC2)o1 +CCNc1ccc(C(=O)N(CC2CC2)C(C)C)nn1 +COC(=O)C1=C(C)N(C)C(=O)NC1c1cc(F)c(F)c(F)c1 +CC(C)(C)c1ccccc1NC(=O)c1cc2ncccn2n1 +O=C1CCN(CCC(=O)c2ccc3c(c2)CCCO3)CC1 +NC(=O)C1CCCN(c2ncnc3cccc(F)c23)C1 +CCC1(CNC(=O)c2c(F)cc(Br)cc2F)CC1 +Cc1ccc(S(=O)(=O)CC(=O)NC(C)CCc2ccccc2)cc1 +COCCn1cc(C(=O)N2CCOC(COC)C2)c2ccccc21 +CCC(=O)NC1(C(F)(F)F)C(=O)N=C(C)C1C#N +Cc1ccccc1N1CC(C(=O)NC(C)(C)C)CC1=O +CCOc1cc(CO)ccc1OCC(=O)N1CCOCC1 +CCCN(Cc1ccsc1)C(=O)c1c(C)nc2ccccn12 +CC(=O)N1CCC(Nc2ccc(OCCc3ccccc3)nc2)CC1 +CC(C)N(C(=O)COC(=O)c1cc2ccccc2[nH]1)C(C)C +CN(CCN(C)C(=O)c1ccc[nH]1)C(=O)OC(C)(C)C +Cc1ccc(C(C(=O)N2CCC3(CCO3)CC2)N(C)C)cc1 +C#Cc1cccc(NCc2ccc(O)c(OCC)c2)c1 +CC1(C)CC2CC(C)(CN2C(=O)c2snc(C#N)c2N)C1 +CC(CC#N)N(C)Cc1ccc(F)c(C#CCO)c1 +O=C(NCc1cc(Br)cs1)c1ccc[nH]1 +CS(=O)c1cccc(NC(=O)c2cc(F)c(Cl)cc2Cl)c1 +COC(=O)c1cc(C)ccc1OC(=O)CCc1cnn(C)c1 +CCC(C)C(C)NS(=O)(=O)c1ccccc1S(C)(=O)=O +COCCNC(=O)CSc1nnc2c3cc(C)ccc3n(C)c2n1 +COc1cc(Cl)ccc1C(=O)Nc1cccnc1 +CC(O)(CNC(=O)c1cccc(-n2cccn2)n1)c1ccccc1 +CCCN1CCN(S(=O)(=O)c2ccc(NC(C)=O)cc2)CC1 +C#CCN1CCN(S(=O)(=O)c2ccc(C)c(NC(C)=O)c2)CC1 +NC(=O)CCc1nnc(SC2CCCC2)n1CC1CCCO1 +O=C(Nc1cccc(Cl)c1Cl)c1cc2n(n1)CCCO2 +O=C(NCc1cscn1)N1CCOCC1C1CC1 +Cc1cccc(C)c1NCc1cccc2cccnc12 +O=C(Nc1ccccc1C(=O)NC1CC1)c1ccoc1 +CCCN1C(=O)c2[nH]nc(-c3ccco3)c2C1c1cccs1 +CCOC(=O)Nc1ccc(S(=O)(=O)Nc2cccc(F)c2)cc1 +CCC(NC(=O)CN(C)C(=O)OC(C)(C)C)c1nc2ccccc2[nH]1 +CCCNC(=O)c1ccc(C)c(NC(=O)c2ccccc2)c1 +CCOc1ccc(F)c(C(=O)Nc2cc(OC)ccc2OC)c1F +NC(=O)c1c(NC(=O)c2cc(Cl)ccn2)sc2c1CCCC2 +O=C(c1cnn2cccnc12)N1CCCC1c1ccc(F)cc1 +O=C(CNC(=O)c1ccccc1)Nc1cccc2cccnc12 +Cc1ccc(C(=O)NCC(=O)NCCc2ccccc2)s1 +O=c1[nH]cc(-c2cc(NCc3ccccn3)nc3[nH]ccc23)c(=O)[nH]1 +CCn1cc(C(=O)N2CCOC(c3nc(C)n[nH]3)C2)cn1 +Cc1noc(CNC(=O)C2CCN(C(=O)C3CCC(=O)N3)CC2)n1 +CCc1nn(C)cc1CN1CCN(C)c2ccc(Cl)cc21 +Cn1cnnc1-c1cccc(NC(=O)Cn2c(=O)[nH]c3ccccc32)c1 +Cc1cc(C(=O)C(C#N)c2nc(-c3ccc(Cl)cc3)cs2)no1 +Cc1ccc2onc(CNC(=O)N3CCC(C(N)=O)CC3)c2c1 +Cc1cc(C)c(C(O)CNCc2ccco2)c(C)c1 +O=C1CCSc2c1cccc2C(=O)N1CCc2ccccc2C1 +COc1ccccc1NC(=O)CNc1cc(S(C)(=O)=O)ccc1C +COCCNC(=O)CCNC(=O)Nc1ccccc1C +Cc1noc(C)c1CCC(=O)N1CCOC(C)C1 +CC(C)c1nc(CCNC(=O)NC(C)c2ccncc2)cs1 +COc1ccc(NC(=O)c2nn(-c3ccc(F)cc3)ccc2=O)cc1 +Cc1cc(C)cc(COCCOCn2cc(C)c(=O)[nH]c2=O)c1 +C#CCNc1cc(C(=O)NCC(F)(F)F)cc(F)c1C +NC(=O)Cc1ccccc1NC(=O)NC1CCc2c(Cl)cccc21 +CCn1nnc2c(SCC(=O)NC3CC3)ncnc21 +Cc1nc(C2(NC(=O)c3ccc(OC(C)C)nc3)CCCC2)no1 +CN(Cc1ncccc1C(F)(F)F)C(C(N)=O)c1cccc(F)c1 +Cc1csc(SCc2nc(-c3ccncc3)nn2C)n1 +O=C(Nc1nccs1)c1cn(CC2CCCO2)cc2c(=O)[nH]nc1-2 +COc1ccc(C(=O)N(C)Cc2ncc(C)c(OC)c2C)cc1 +c1cc(-c2nn3c(-c4cnccn4)nnc3s2)ccn1 +CS(=O)(=O)N1CCCN(C(=O)c2ccc[nH]c2=O)CC1 +O=C1COc2cc(NC(=O)c3cccc4ccccc34)ccc2N1 +CC(C)(C)OC(=O)N1CCCN(c2nnc(C3CC3)s2)CC1 +O=C(Cc1csc(-c2cccs2)n1)N1CCCC1 +Cc1csc2ncn(C3CCC(=O)N(C)C3)c(=O)c12 +CC(NC(=O)N1CCCCC1CCO)c1ccc(-n2ccnn2)cc1 +CC(OC(=O)c1cc2sccc2n1C)C(=O)NCc1ccco1 +COc1cc(C(C)=O)ccc1OCC(=O)Nc1c(C)cc(C)cc1C +C#CCOC(=O)Nc1cc(C(F)(F)F)cnc1OC +Cc1nc2c(s1)C(N(C)Cc1cc(F)c(F)cc1F)CCC2 +Cc1cccc(-c2nnc(-c3ccc(C(=O)N4CCC4)cc3)o2)c1 +Fc1ccc(-c2cn3nc(N4CCOCC4)sc3n2)cc1 +Cc1ccc(F)cc1NCC(=O)NC1(C#N)CCCC1 +O=C(NCC(F)(F)F)c1nc2c(s1)COCC2 +O=C(OCC1CCCO1)c1ccccc1OCC1CCCO1 +COCC(C)NS(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +COc1ccc(C(N)=O)c(OCC(=O)c2ccc(F)c(F)c2)c1 +COc1ccc(CN(C)C(=O)NC(C)c2c(C)noc2C)cc1 +CSc1ncc(CN2CCCC(c3cc4cccnc4[nH]3)C2)cn1 +O=C(Cc1ccc(F)cc1F)NCCNC(=O)CC1CCCCC1 +CNC(=O)c1ccc(OC)c(NCC(=O)N(C)C2CCC(C)CC2)c1 +Cc1cc(C)n2nc(SCC(=O)Nc3ccccc3Cl)nc2n1 +COc1ccc(F)cc1S(=O)(=O)N1CCOCC1 +COc1cccc2c1OCC(Cc1cc(C(=O)NC(C)C)ccn1)C2 +COc1ccccc1Oc1ccc(NC(=O)c2cc(C)on2)cc1F +CC(=O)NC1CCCN(C(=O)NCCc2ccc(OC(C)C)cc2)C1 +CC(=O)N1CCN(c2ncnc3sc4c(c23)CCCC4)CC1 +O=C(NCCN1CCOCC1)NCC1(c2ccccc2)CCOCC1 +CCCNc1nc(NCc2ccccc2OC)c2cnn(C)c2n1 +NC(=O)C1CCCN(C(=O)c2ccccc2Cc2ccccc2)C1 +COc1cc2c(cc1F)C(c1cccnc1F)NCC2 +CC(C)(C)c1ccc(S(N)(=O)=O)cc1OC1CC1 +O=C(NCC(O)c1ccccn1)c1c[nH]nc1-c1cccc(F)c1 +CC(=O)Nc1ccc(-c2ccccc2-c2nnc(C)o2)cc1 +COCC(O)CN(C)C(=O)c1ccc2ncsc2c1 +CCCOc1cc(C)ccc1NC(=O)NC(C)COC +CC(N(C)C(=O)CNS(=O)(=O)c1cccs1)C(C)(C)C +Cc1noc(C)c1S(=O)(=O)NCC1CCOC1 +COc1ccc(OC)c2nc3c(cc12)c(N)nn3CCO +Cc1ccc(-c2ncco2)cc1NC(=O)c1cc(-c2ccco2)[nH]n1 +Cc1nn2cccnc2c1C(=O)N1CCC(Oc2ccccc2)CC1 +COC(=O)C(NS(=O)(=O)c1cc(C)ccc1F)C(C)(C)C +COc1ccc(S(=O)(=O)NCc2cccc(C)n2)cc1C +Cc1ccc(C)c(NC(=O)CSc2nc(C)cc(=O)[nH]2)c1 +Cc1cc(C(=O)NC2CCN(c3ncccn3)CC2)on1 +CCOC(=O)N1CCC(NC(=O)c2ccccc2SC)CC1 +NC(=O)CCCNC(=O)CSc1ccc(F)cc1 +CCOC(=O)Nc1ccc(NCc2cccc(O)c2)cc1 +COc1ccnc(N2CCN(C(=O)c3csnn3)CC2)n1 +Cc1cnc(C(=O)N2CCCC(c3[nH]ncc3-c3ccncc3)C2)cn1 +O=C(NC1CC1)NC1CCN(c2c(F)cccc2F)C1=O +CN(CC(N)=O)C(=O)c1cc2c(s1)CCCCC2 +COCC(=O)N1CCc2sccc2C1c1ccc(N)cc1 +CCC(Oc1cccc(N)c1)C(=O)c1ccccc1 +CNC(=O)Cc1csc(C(C)(C)c2ccc(N)cc2)n1 +COc1ccnc(NC(=O)c2ccn(-c3ccccc3)n2)c1 +Brc1ccc(-n2nc(C3CC3)c3c2CCNC3)cc1 +COc1ccc(C2CC(=O)c3cn4ncnc4nc3C2)cc1 +CCC1CCCCC1NC(=O)CCCn1cncn1 +CC(C)OC(=O)c1sc2nc(-c3cccnc3)ccc2c1N +O=C(Cn1ccccc1=O)Nc1ccc(N2CCNC2=O)cc1 +NS(=O)(=O)CCNC(=O)CCC(=O)c1cccs1 +Cc1nnc(C(C)Sc2nnc(-c3ccc(F)cc3)n2C)o1 +CCN(C)C(C(=O)Nc1ccc2c(c1)C(=O)NC2)c1ccccc1 +O=C(CNC(=O)c1n[nH]c(=O)c2ccccc12)Nc1ccc(F)cc1 +COc1ccc(-c2n[nH]cc2C(=O)N(C)CC(=O)NC(C)C)cc1 +CCC(C)CN1C(=O)C(C)NC12CCN(C(=O)C1CCC1)CC2 +CS(=O)c1ccc(C(=O)Nc2ccc(F)c(C#N)c2)cc1 +CCS(=O)(=O)NCCCNC(=O)c1c(F)cccc1Cl +COc1ccc(Nc2nnc(SCC#N)s2)cc1OC +Cc1[nH]c(C(=O)NC2CC2)c(C)c1S(=O)(=O)N1CCC(C)CC1 +Cn1cnnc1SCC(=O)Nc1c(F)cccc1F +CC(=O)Nc1ccc(Cc2ccc3[nH]c(=O)cc(C)c3c2)cc1 +COc1ccc(Br)c(C(=O)N(C)CCc2ccccc2)c1 +CNc1cncc(C2CCN(C(=O)c3cccnc3)CC2)n1 +CNCC(=O)c1cc2cc(Br)ccc2s1 +CCn1c(SCCNS(=O)(=O)CC)nc2ccccc21 +O=C(CCS(=O)(=O)c1ccccc1)Nc1ccc2sccc2c1 +COc1ccc(C(C#N)CCC(=O)NC2CC2)cc1Cl +COc1ccc(NC(=O)c2ccc(S(C)(=O)=O)cc2)c(OC)c1 +CCCN(CC1CC1)C(=O)Nc1ccc(-n2ncn(C)c2=O)cc1 +COCc1ccc(C(=O)N2CCC(C(O)c3ccccc3)CC2)o1 +CC(C)(C#N)NC(=O)c1cc2cccc(Br)c2o1 +CCNC(=O)C(C)NC(=O)NC(C)c1ccc(Br)cc1 +CCN(CC(F)(F)F)C(=O)c1ccc(NC(=O)C2CC2C)cc1 +CC(C)(C)n1ncc2c1CCCC2NS(=O)(=O)c1cccs1 +CCOCCCNC(=O)Nc1ccc2c(c1)COC2 +CCOc1ccc(NC(=O)c2cc(C(C)=O)c[nH]2)cc1Cl +Cc1nc(C2COCCN2c2ncc(C(F)(F)F)cc2Cl)no1 +CCCCn1nc(-c2cccnc2)cc(C#N)c1=O +COc1ccc2c(c1)OCC(C(=O)N1CCC3(CCCO3)CC1)C2 +Cc1ccc(OCCCCNC(=O)c2cn3cccnc3n2)cc1 +O=C(Nc1ccc2c(c1)OCCO2)C1COc2ccc(F)cc2C1 +O=C1COc2cc(C(=O)Nc3ccccc3)ccc2N1 +CCC(NC(=O)CCn1ccccc1=O)c1cccc(Cl)c1 +Cc1occc1CN(C)C(=O)c1cnc2c(c1)c(C)nn2C +COC(=O)C(NC(=O)c1[nH]c(C)c(C(C)=O)c1C)C(C)C +COc1ccnc(NC(=O)c2cn(-c3cccc(C)c3)nn2)c1 +CC(=O)c1cccc(NC(=O)CCCNC(=O)c2ccccc2)c1 +Cc1ccoc1C(=O)N1CCCn2cnc(COC(C)C)c2C1 +O=C(CNc1ncc(Cl)cn1)Nc1ccccc1Br +N#Cc1cnc(NC(=O)COc2ccccc2F)s1 +CCC(NC(=O)C1(c2cccc(F)c2)CCC1)C(=O)OC +N#CCCN(CCC#N)C(=O)CSc1nnc2n1CCCCC2 +CNc1ncc(Br)cc1C(=O)Nc1ncc(C)s1 +COCC(O)CN(C)C(=O)Nc1ccc(C)c(C(F)(F)F)c1 +NC(=O)CCCNC(=O)Nc1nnc(C(F)F)s1 +CCS(=O)(=O)c1ccccc1NCc1ccc[nH]1 +Cc1cccc(C)c1OC(C)c1[nH]nc(C)c1CO +CCNC(=O)c1ccc(NC(=O)c2ccc(OC)c(OC)c2)c(C)c1 +CC(NS(=O)c1ccc(N)cc1)c1ccccc1 +Cc1ccccc1-n1cc(-c2cc(C3CCOC3)c(C#N)c(N)n2)cn1 +CC(C)c1nc(OCC(N)=O)c(C#N)c2c1COC(C)(C)C2 +Cc1ncccc1C(=O)N1CCC(C(=O)Nc2ccccn2)CC1 +Cc1cccc(C(=O)NC2CCCN(Cc3ccccc3)C2=O)c1C +CCOC(=O)C1CC(=O)N(c2nnn(CC)n2)C1 +CN(C(=O)CC1C=CCC1)c1nc2ccccc2o1 +NC(=O)c1ccc(NC(=O)CCc2cccc(F)c2)cc1 +Cc1occc1C(=O)Nc1ccc(-c2nc(C(C)C)no2)cc1 +N#CCCSc1nccn1Cc1ccccc1F +Cc1nn(CC(=O)NC2CC2)c(C)c1S(=O)(=O)N1CCOCC1 +O=C(NC1CCN(C(=O)c2ccoc2)CC1)c1sccc1C1CC1 +CCCCCNC(C#N)c1ccc2c(c1)OCCO2 +COc1ccc(-n2cnc3c2N=C(O)CC3c2ccc(F)cc2)cc1 +COCC#CCn1c2c(sc1=O)CC(C)CC2 +CC(C)(C)c1nc(CN2CCc3c(N)cccc3C2)cs1 +CC(C)=Cc1nc(CC(C)N(C)C(=O)OC(C)(C)C)no1 +CNC(=O)Nc1cccc(-c2nccnc2N2CCCCC2)c1 +CCCS(=O)(=O)N1CCN(CC(F)(F)F)CC1 +COc1ccccc1NC(=O)c1cc(S(C)(=O)=O)ccc1C +Cc1cc(C(=O)Nc2ccccc2N2CCCC2)c(C)n1C(C)C +CCNC(=O)CN(CC)c1c(N)cccc1Cl +CCCC(=O)Nc1cnn(Cc2cccc(F)c2)c1 +CC1(C)C(=O)Nc2ccc(C(O)c3ccccc3)cc21 +Cn1ccc(C(=O)Nc2nc3c(cc4c5c(cccc53)CC4)s2)n1 +Cc1ccc(Cl)cc1NC(=O)c1cc(Br)cnc1N +CCCS(=O)(=O)NC(CC)C(=O)N1CCNCC1 +CCc1[nH]c(C(=O)N2CCC(C)CC2C)c(C)c1C(=O)OC +O=C(CCn1ccc2ccccc21)N1CCN(C2CCCC2O)CC1 +CC1COCC(C)N1Cc1cccc(-n2cccn2)c1 +COc1ccc(-c2cnc(CCC(=O)N3CCC(C)CC3)o2)cc1 +CCc1ccc(CNC(=O)Nc2cccc(C#N)c2)s1 +CCn1c(=O)n(CC(=O)NCC(O)c2ccco2)c2ccccc21 +Cc1nc(C)c(C(=O)N2CCCC2c2nc3ccccc3[nH]2)s1 +Cc1ccc(NC(=O)c2cc3sccc3n2C(C)C)nc1 +COc1cccc(NCC(=O)N2CCc3ccccc3C2)c1 +COc1ccc(CCC(=O)NCC(C)(O)c2ccccc2)cc1 +Nc1cc(NS(=O)(=O)c2ccc(Cl)cc2)ccc1F +COc1ccccc1-n1nnnc1SCc1n[nH]c(=O)[nH]1 +Cc1ccc(OCC(=O)Nc2cc(-c3ccncc3)no2)cc1 +CN(C)C(=O)CCc1ccc(NC(=O)c2cccs2)cc1 +COc1cccc(CC(O)c2ccc(OC)c(OC)c2)c1 +Cc1ccc(NC(=O)c2cccc(N3CCCC3=O)c2)cc1Cl +CC(NC(=O)Nc1cn[nH]c1)c1ccc(NC(N)=O)cc1 +COCCOCC(=O)N(C)C(C)c1ccc(Cl)cc1Cl +COC(=O)c1ccc(CNC(=O)NCCc2ccco2)cc1 +CC(C)Oc1ccccc1CNc1cccc(N2CCCC2=O)c1 +O=C(NCCSc1ccccc1)N1CCOCC1C1CC1 +CCC(=O)N1CCc2ccc(C(=O)N3CCCCCC3)cc21 +CCc1cnc(N)nc1N1CCC(O)(c2ccc(F)cc2)CC1 +O=C(Nc1ccc(Cl)cn1)c1ccc(F)cc1F +COc1ccc(-c2cc(CO)nn2CCCO)cc1C +COc1ccc(C(=O)NC(C)Cc2ccco2)c(O)c1 +CCCCC(NC(N)=O)C(=O)Nc1ccc(-n2ccnc2C)nc1 +CN(C)c1ccc(-c2nnc3c(n2)c(=O)n(C)c(=O)n3C)cc1 +CCN(CC(=O)NC(C)C)S(=O)(=O)c1ccc2c(c1)CCCC2 +O=c1c2ccccc2nnn1CCc1ccccc1 +COc1ccc(Cl)cc1N(C)C(=O)C1CCC1 +O=S(=O)(c1ccccc1F)N1CCC(c2ccsc2)CC1 +COc1ccc(-c2nnc3[nH]c4ccc(N)cc4n23)cc1OC +Cc1nsc(C(=O)NCc2nc3ccccc3[nH]2)n1 +N#CCCN(Cc1ccco1)S(=O)(=O)c1ccc(F)cc1Cl +CN(CC1CCCO1)C(=O)NCc1cccc(OCC(F)(F)F)c1 +O=C(NC1CC2C(=O)NCC(=O)N2C1)c1c[nH]nc1C1CCCCC1 +CCOC(=O)CC1CCCCN1C(=O)CCc1ccc(=O)[nH]n1 +CCC1CN(C(=O)c2ccc3nccn3c2)CC1N1CCOCC1 +C#CCNC(=O)C(NC(=O)Cc1ccc2ccccc2c1)C(C)C +COc1ccc(OC)c(CN(C)C(=O)c2cc(C(C)C)[nH]n2)c1 +Cc1cc(Cl)ccc1NC(=O)Cn1c2c(sc1=O)CCCC2 +Cc1nc(NCc2ccncc2)c(C#N)c2c1CCCC2 +COc1ccccc1NC(=O)CN1CCN(C(=O)C2CCCO2)CC1 +C#Cc1cccc(NC(=O)c2cc(OC)ccc2O)c1 +CCC(CC)N(C)C(=O)c1ccc(NC(N)=O)cc1 +Cc1ccc(C(C)N(C)S(=O)(=O)N(C)CCC#N)cc1 +CCC(C)(CNC(=O)Nc1nccs1)N1CCOCC1 +COC(=O)Cc1csc(NC(=O)c2cccc(CC#N)c2)n1 +O=C(NCc1ccc(-n2ccnc2)cc1)C1CCOc2ccccc21 +Cc1ccc(Cc2nc(C(=O)N3CCNC(=O)C3(C)C)cs2)cc1 +Nc1cccc2c1CN(c1ccc(F)c(F)c1F)C2=O +COc1cc(NC(=O)C2CC2)c(OC)cc1NC(=O)c1ccco1 +COCCN1CC(C(=O)N(CC2CCCCC2)C2CC2)CC1=O +Cc1cc(C)c(CN(C)Cc2nccs2)cc1C +Cc1cnn(-c2ccncc2NCc2cnc(-c3cccnc3)s2)c1 +CC(C)(CO)c1nnc(C(N)c2ccccc2C#N)o1 +CC1CCC(N(C)C(=O)c2cc(C3CC3)on2)CC1 +Cc1cc(C)c(S(=O)(=O)NCC(O)(c2ccco2)C2CC2)cc1C +O=c1c(Br)c[nH]c2ccc(OC(F)(F)F)cc12 +Nc1cccc(S(=O)(=O)N2CCCCC2c2cccnc2)c1 +Cc1ccccc1C(=O)N(Cc1cccnc1)Cc1ccco1 +COc1ccc(C(C)NS(=O)(=O)C(C)C)cc1Br +COc1ccc(CNC(=O)c2ccc(C)c(NC(C)=O)c2)cc1 +CC(C)Cn1ccnc(Sc2ccncc2N)c1=O +CCCCN1C(=O)C(C)(C)Sc2ccc(N)cc21 +COc1ccc2c(C(C)=O)cn(S(=O)(=O)c3ccccc3)c2c1 +CCOc1ccc(C(C)C)cc1S(=O)(=O)n1ccc(C)n1 +Cn1c(=O)[nH]c(=O)c2c1nc(NCCCO)n2Cc1ccc(F)cc1 +Cc1ccccc1CN(C)C(=O)c1cn2ccccc2n1 +Cc1cccc(CNS(=O)(=O)c2ccc3c(c2)CCC(=O)N3)n1 +COc1cccc(C(=O)N(Cc2ccc3[nH]ccc3c2)C2CC2)c1 +CC1=CC(C)(C)N(C(=O)CSc2nnc(C)s2)c2ccccc21 +CCCOc1ccccc1Nc1nc(C)c(CCO)c(=O)[nH]1 +C=CCNC(=O)CC(C#N)c1c(C)cc(C)cc1C +CC(=O)c1cccc(S(=O)(=O)N(C)c2ccccc2F)c1 +CCOc1ccc(C2=CCN(C(=O)c3ccc(C)[nH]c3=O)CC2)cc1 +CC(=O)c1csc(C(=O)NCCOc2ccc(Cl)cn2)c1 +COc1cc(C(C)=O)ccc1OS(=O)(=O)c1ccc2c(c1)CCC2 +COc1ccc(CSc2nnc(C)n2N)cc1Cl +CC(=O)Nc1cccc(-c2cc(C#N)nn2CC(C)C)c1 +Cc1noc(C)c1CC(=O)Nc1cccnc1-n1ccnc1C +CCOCCn1c(=O)[nH]c2cc(C(=O)N(C)C)ccc21 +COc1ccc(N(C(=O)CCc2ccccn2)C(C)C)cc1F +COC(=O)c1c(NC2OC(=O)c3ccccc32)sc(C(C)=O)c1C +Cc1ccc(NC(=O)Cn2ccc(=O)[nH]c2=O)cc1Br +Cc1ccc(NC(=O)c2c[nH]nc2-c2ccccc2F)cc1 +CCOc1ccc(C(=O)Nc2nc(C)c(C(=O)N(C)C)s2)cc1 +CCOc1ccc(C(F)(F)F)cc1NC(=O)N(C)CCO +CC(CC(=O)Nc1ccc(C(N)=O)nc1)c1ccc(F)cc1F +Nc1ccc(C(=O)N2CCCC2)cc1Br +Cc1cccc(N2CCN(Cc3nc(N)nc(N)n3)CC2)c1C +Cc1ccc(N2CC3(CCN(C(=O)c4ccccn4)C3)CC2=O)s1 +COc1ccc(Br)cc1NC(=O)C(C)NC(N)=O +COc1cccc(CN(C)C(=O)CNc2ccc(C(N)=O)cc2)c1 +CN(C)C(=O)N1CCN(Cc2n[nH]c(=O)[nH]2)CC1 +CC1=C(C(=O)N(C)C)C(c2ccc(C#N)cc2)NC(=O)N1 +CC1C(=O)N(c2cccc(F)c2)CCN1Cc1ccc(F)cc1F +COC(=O)CCCN(C)S(=O)(=O)c1cccs1 +CCC(CO)N(Cc1ccco1)C(=O)c1c(C)[nH]c(C(C)=O)c1C +Cc1cccc(-n2nc(C)nc2C2CCCCN2C(=O)C2CC2)c1 +CC(C)CC1COCCN1C(=O)Nc1ccc2c(c1)COC2 +Cc1ccccc1OS(=O)(=O)c1cc(C(N)=O)n(C)c1 +CN(CCN1CCOCC1)C(=O)Nc1cccc(SC(F)F)c1 +O=C(CCN1CCc2cc(F)ccc2C1)NC1CCCC1 +Cc1ccnc2nc(-c3nc(CC(=O)NC4CCCCC4)no3)nn12 +Clc1ccccc1CN(Cc1ccncc1)Cc1ccccn1 +COC(=O)N1CCC(NS(=O)(=O)c2ccc(Cl)cc2)CC1 +N#CCSc1nnc(CNc2cccc(Cl)c2)o1 +COC(=O)CC1C(=O)NCCN1c1ncnc2ccsc12 +CC(=O)N1CC(C(=O)NCc2nc3ccccc3[nH]2)C1 +CCc1cc(N)cc2c(=O)cc(C(=O)NCCCOC)oc12 +CCOc1ccccc1-c1csc(NC(=O)C2CC2)n1 +N#CCCC(C#N)CN1CCN(c2cccc(Cl)c2)CC1 +Cc1ccc2[nH]nc(C(=O)Nc3cccc(C)n3)c2c1 +NC(=O)Cn1cc(NC(=O)CCN2CCOC2=O)cn1 +CCC1CCC(NC(=O)N2CCC(NS(C)(=O)=O)CC2)CC1 +Cn1cccc1C(=O)N1CC2(CCN(C(=O)c3cscn3)C2)C1 +O=C(NC1CCCn2ncnc21)c1ccnc(OC2CCC2)c1 +CCOc1ccc(C(=O)NC2CCCc3[nH]c(=O)ccc32)cn1 +O=C(NCCOc1cccc(Br)c1)NCc1ccco1 +NC(=O)c1ccc(NCc2ccc(Cl)cc2)cc1Cl +Cc1cc(NC(=O)NCCCc2c(C)noc2C)ccc1C(N)=O +CN(CC(N)=O)C(=O)C1CCCN(c2ncccc2C(F)(F)F)C1 +O=C(NCCN1CCN(C(=O)C2CC2)CC1)c1cccs1 +Cc1cc(C)c(CNC(=O)NCC2(c3ccc(F)cc3)CC2)c(=O)[nH]1 +O=C(CSc1nccn1C1CC1)Nc1ccccc1C(F)(F)F +CC(C)CC(=O)N(Cc1ccc2cc[nH]c2c1)C1CC1 +COc1c(Cl)cccc1NC(=O)c1cccnc1-n1cccn1 +O=C(COc1ccc2ccccc2c1)Nc1cnoc1 +CNC(=O)c1cc(-c2ccc(OCCC(C)C)cc2)nc(N)n1 +Cc1cc[nH]c(=NS(=O)(=O)c2c(F)cccc2F)c1 +CC(=O)Nc1ccc2c(c1)nc1n2CCN(Cc2ccccc2)C1 +CC(Cc1ccccc1F)NC(=O)Cn1c(=O)n(C)c2ccccc21 +Cc1cc(C)n2cc(CNc3cccc(F)c3F)nc2n1 +CCc1cc(=O)[nH]c(SCC(=O)Nc2cccc(C)c2)n1 +CCN(CC1CC1)C(=O)CNC(=O)c1ccc(C)c(C)c1 +COc1ccc(CN2CCOC(c3noc(C)n3)C2)c(Cl)c1 +COCCCNC(=O)c1ccn(C2CCCC2)n1 +Cc1cccc(-c2ocnc2C(=O)NC(C)Cc2ccco2)c1 +Cc1ccc(SCC(F)(F)F)c(NC(=O)N2CCC(O)C2)c1 +Cc1c(C(=O)N2CCCC2c2ccsc2)cnn1C +CCC(C)(C)C(=O)N1CCN(c2ccccc2)CC1 +Cc1[nH]nc(C(=O)Nc2cccc(Cl)c2)c1N +COC(CNS(=O)(=O)c1cccc2cccnc12)c1ccsc1 +O=C(NCCc1ccc2c(c1)OCCO2)Nc1ccncc1 +CCCN(CC(=O)N(C)C)C(=O)c1c[nH]c2cccc(F)c12 +CCCc1nnc(NC(=O)c2ccc3[nH]c(C)cc(=O)c3c2)s1 +O=C(CCc1ccccc1)Nc1nnc2ccccn12 +COc1ccc(Cl)cc1-c1nc(-c2ccc3nnc(C)n3c2)no1 +CCC(=O)NCC(=O)OCc1csc(-c2ccccc2Cl)n1 +Cc1cnc(NC(=O)Cc2ccc(Cl)cc2Cl)s1 +CC(C)CCNC(=O)c1c(-c2cccnc2)cnnc1N +N#CCC(=O)Nc1ccc(C(=O)OCC(N)=O)cc1 +CCC(=O)c1ccc(OCC(=O)Nc2ccc(C)cn2)cc1 +CSc1nnc(SCc2nc(C)c(C)o2)s1 +CC(C)CNC(=O)c1cccc(CN2C(C)COCC2C)c1 +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1cccc(-n2cccn2)c1 +CCCCCNC(=O)c1ccc(OCC)c(N)c1 +Cc1nnc(NC(=O)N2CCCC2c2ccccn2)s1 +Cc1cc(F)ccc1CCNC(=O)N(C)CC1CCCO1 +O=C(COC(=O)Cc1ccc(-c2ccccc2)cc1)NC1CC1 +COCCOCC(=O)N1CCN(c2cccc(Cl)c2)C(=O)C1 +Cc1n[nH]c(C)c1CCC(=O)NC(C)(C)CC(C)(C)C +O=C(CCC(=O)N1CCC(O)CC1)c1ccc(Cl)cc1 +COc1cc(Cl)c(C)cc1NC(=O)c1cccc(NC(N)=O)c1 +CCc1cc(=O)n2c(n1)SCC2CC(=O)NC1CCCCC1C +COC(=O)c1oc(C(C)N2CC3OCCN(C)C3C2)cc1C +CCCNc1cccc(C(=O)N(C)C(C)CC#N)n1 +O=C(c1cccnc1)N1CCN2CC(Oc3cncnc3)CC2C1 +CC(OCC(F)(F)F)C(=O)Nc1ccc2c(c1)COC2 +CCN(CC)C(=O)c1ccccc1NC(=O)c1cccc(N(C)C)c1 +CCN1CC(C(=O)OC)C(=O)c2cnc(SC)nc21 +CCNS(=O)(=O)c1cccc(C(=O)Nc2ccc(OC)cc2)c1 +CCOc1ccc(C(=O)Nc2ccc(C(N)=O)cc2)cc1OCC +CCc1ccc2c(CC(=O)Nc3ccc(C(N)=O)cc3)coc2c1 +Nc1ccc(-c2nc(CCNc3ccc(F)cc3)n[nH]2)cc1 +O=C(NCc1ccccn1)c1ccccc1-n1cnnn1 +CC(=O)c1cnn(-c2ccccc2Br)c1C +CC(=O)Nc1cccc(NCCC(O)c2ccc(F)cc2)c1 +COCc1csc(NC(=O)c2cnc3ccc(C)cn23)n1 +Cc1ccc(-n2nc(C)c(NC(=O)CN(C)CCC#N)c2C)cc1 +COC(=O)c1ccc(C(=O)N2CCN(C)CC2c2ccccc2)cc1 +COC(=O)c1sccc1NC(=O)c1ccc(NC(C)=O)cc1 +Cc1ccc(C)c(Nc2ncnc(-n3ccnc3)c2N)c1 +Cc1c(N)cccc1NC(=O)c1ccc(O)c(Cl)c1 +CCC(CC)NC(=O)c1oc2ccc(F)cc2c1C +CCOC(=O)C(C)Oc1ccc2c(=O)c(Cl)coc2c1C +COc1ccc(OCCS(=O)(=O)N(C)c2ccccc2F)cc1 +CCn1c(SC(C)C(=O)N(C)C)nnc1-c1ccc(Cl)cc1 +Cc1cc(C)c(CCNC(=O)N2CCC(n3cncn3)CC2)c(C)c1 +CN(CCc1ccccc1)C(=O)c1ccc(-n2ncc(C#N)c2N)cc1 +CCCS(=O)(=O)NCC1(c2cccs2)CCCC1 +c1ccn(Cc2noc3c2CN(Cc2ccoc2)CC3)c1 +COc1ccc(COC(=O)CC(C)C#N)cc1F +CCCC(=O)N1CCN(c2ccc(C)c(N)c2)CC1 +CC(C)c1nc(CC(=O)N2CCCC(C(N)=O)C2)cs1 +O=C(NCCCC1CCCC1)NCCc1nnc2n1CCCCC2 +Cc1ccccc1C1CC(C)N(C(=O)C(C)c2c(C)noc2C)C1 +O=C1CCCN1CCCOc1ccc(Cl)c(Cl)c1 +Cc1cc(C(=O)Nc2ccccc2SC(F)F)no1 +CC(C)c1nnc2n1CCN(C(=O)c1cnc(-c3ccco3)s1)C2 +Cn1cccc(C(=O)OCc2cc(-c3ccccc3F)on2)c1=O +Cc1cc(=O)oc2c1c(C)nn2-c1ccc(F)cc1 +CC1CCCCC1NC(=O)C1CCCN1C(=O)c1cccs1 +Cc1ccc(C)c(C(=O)NCCCc2cn[nH]c2C)c1 +CCOC(=O)c1nnn(Cc2ccc(Br)cc2)c1C +CC(C)C(NC(=O)Cc1n[nH]c2c(Cl)cccc12)C(=O)NC1CC1 +O=S(=O)(NCc1cccc(Cn2cccn2)c1)c1cccc(F)c1 +COc1ccccc1CNc1nccc2c(N)cc(F)cc12 +CCn1nc(C)cc1C(=O)N1CCC2OCCCC2(COC)C1 +CC(=O)Nc1ccc(-c2csc(Nc3ncccn3)n2)cc1 +CN(Cc1ccccc1)C(=O)c1cc2ccccn2n1 +CCc1ccccc1NC(=O)N1CCCC1c1c(C)noc1C +CCn1nnnc1-c1cccc(NC(=O)NCc2ccccc2)c1 +Cc1c(Br)c2ccccc2n1CC(=O)NC1CC1 +O=C(Nc1cccnc1-n1cccn1)N(Cc1ccccn1)C1CC1 +COCCn1cnnc1C(C)n1ccnc1-c1cc(F)ccc1OC +CC(Sc1cc(-c2ccccc2)ncn1)C(=O)N1CCCC1 +Cc1nn(C)cc1S(=O)(=O)N1CCCC(CN2CCOCC2)C1 +CC(C)S(=O)(=O)c1csc(C(=O)Nc2ccc(F)cc2)c1N +O=C1CN(C(=O)c2cc(-c3ccc(F)cc3)c[nH]2)CCN1 +Cc1[nH]c2ccccc2c1C1=CCN(S(=O)(=O)N(C)C)CC1 +CC(OC(=O)c1cc2ccccc2[nH]1)C(=O)Nc1ccnn1C(C)C +CC(C)N(C)c1ccc(NC(=O)c2scnc2C2CC2)cc1F +CC(c1ccc(F)cc1F)N1CCN(Cc2n[nH]c(=O)[nH]2)CC1 +Cc1nnc(SCC(=O)Nc2cccc(Cl)c2)n1C1CC1 +CCCNC(=O)COc1c(Cl)cc(C#N)cc1OC +CC(=O)Nc1cccc(C(=O)NC2CCCCC2)c1C +O=C(Nc1cccc2cccnc12)c1cccc(O)c1 +N#CC(C(=O)c1ccc(Cn2ccccc2=O)o1)c1ccccn1 +CC(C)C(=O)NC(NCc1ccco1)C(Cl)(Cl)Cl +CCc1cn[nH]c1C1CCCN(C(=O)c2cnc(C(C)C)nc2C)C1 +Cn1nc(C(=O)Nc2cccnc2)cc1NC(=O)CCc1ccccc1 +N#Cc1ccccc1NC(=O)c1cccc(Cl)c1 +COc1ccc(C(=O)N(C)C)cc1NC(=O)Cc1c(F)cccc1F +N#CC1(c2ccccc2)CCN(S(=O)(=O)c2ccc(N)cc2)CC1 +CN(CC(F)(F)F)C(=O)CNC(=O)NC1(c2cccc(F)c2)CC1 +CCN(C(=O)c1sc(C)nc1C)C1CCN(c2ccccc2)C1=O +Cc1csc(N2CCN(C(=O)c3c(C)noc3C(C)C)CC2)n1 +O=C(Nc1ccc(-n2cncn2)c(F)c1)c1ccc(-n2ccnn2)cc1 +CCN(CC)C(=O)CCC(=O)N1CCCc2cc(C)cc(C)c21 +CN(Cc1cccnc1)C(=O)c1ccccc1COc1ccccc1 +CCC(Oc1ccccc1Cl)C(=O)Nc1cc(C)on1 +COc1ccc(CNc2cccc(C(C)=O)c2)cc1C +O=S(=O)(Cc1ccccc1)NC1CCSc2ccccc21 +COc1ccc(-c2oc3c(C)cccc3c(=O)c2O)cc1OC +Cc1cc2cc3c(cc2nc1SCC(N)=O)OCCO3 +CN(CCC(F)(F)F)C(=O)c1cccc(NC(N)=O)c1 +CC(C)CNC(=O)NCC(=O)NCc1ccccc1 +CCC(C)OC(=O)CN1C(=O)COc2cccc(N)c21 +CCCCc1nnc(NC(=O)Cc2ccon2)s1 +CN(C(=O)NC1CC1)C(c1ccccc1)c1ccccn1 +COc1ccccc1-c1ncc(CNc2nnc(C)o2)s1 +COc1ccc2oc(C)c(C(=O)N(C(C)C)C3CCC3)c2c1 +Cc1n[nH]cc1NC(=O)CCNC(=O)c1cccs1 +CC(=O)Nc1cc(NC(=O)NCCC2=CCCCC2)ccc1C +Cc1cccc(C)c1NC(=O)c1cc(=O)c2cc(N)ccc2o1 +CS(=O)(=O)c1ccc(C(=O)c2ccccn2)o1 +CC(=O)Oc1ccccc1C(=O)Nc1cccc(C)c1 +Cc1cc(=O)n2nc(NCc3ccccc3C)sc2n1 +COCCn1cc(NS(=O)(=O)c2ccc3ccccc3c2)cn1 +COc1cc(Br)ccc1S(=O)(=O)n1ccnc1 +N#Cc1cc(F)c(N2CCC(C(=O)N3CCCC3)CC2)c(F)c1 +Cn1ccc(NC(=O)Cn2cc(Br)c(=O)[nH]c2=O)n1 +COc1cccc(C(NC(=O)Nc2cc(C)on2)c2nccn2C)c1 +Cc1cccc(Cn2ccnc2S(C)(=O)=O)c1 +CN(C(=O)c1ccc(S(=O)(=O)N(C)C)o1)c1ccccc1 +Cc1nc(C)n(CC2CN(CC=Cc3ccccc3)CCO2)n1 +CC(=O)c1ccc(OCC(=O)N=c2[nH]nc3cc(C)ccn23)cc1 +COc1ccc(N(Cc2ccccc2)C(=O)CNC(=O)C2CC2)cc1 +CCc1nnc(SCC(=O)Nc2ccccn2)n1N +CC(C)CC1COCCN1CC(=O)N1CCCC(C)C1 +COc1ccc(S(=O)(=O)NCC(OC)c2ccccc2)cc1 +Nc1ccc(Cl)c(NC(=O)c2cccc(Cl)c2)c1 +CC(NC(=O)CNC(=O)C(C)(C)C)c1ccccc1F +OC(CNc1ccccc1F)c1ccc2c(c1)OCO2 +Cc1cccc(C)c1NC(=O)c1sccc1Br +COc1ccc(O)c2c1C(c1ccc[nH]c1=O)NCC2 +Cn1cnnc1-c1ccnc(NCc2ccc(Br)cc2)c1 +COCCNC(=O)C1CCC(C)N(C(=O)c2cccc(C)c2C)C1 +CC(C)(C)C(=O)NCCc1cc(N2CCOCC2)nc(NC2CC2)n1 +CCC(=O)Nc1ccc(OCc2cc(=O)n3ccc(C)cc3n2)cc1 +Cc1ccc(CN(C)C(=O)NC2CCN(CC(F)(F)F)C2)s1 +NC(=O)c1cccc(COC(=O)C2(c3ccc(Cl)cc3)CC2)c1 +Cc1cc(C(=O)N2CCc3ccc(O)cc3C2)on1 +COC(=O)c1sccc1S(=O)(=O)NCc1ccccc1Cl +Cc1cccc(C(=O)OCCNC(=O)c2ccncc2)c1F +Cc1cc(NCCO)c2[nH]nc(-c3ccsc3)c2n1 +CCNC(=O)CNS(=O)(=O)c1ccc(N)cc1Cl +COc1cc2ncn(Cc3cccc(N)c3)c2cc1OC +Clc1cccc2nc(NCc3ccccn3)sc12 +CCC(C)NC(=O)c1ccc(NC(=O)c2ccc(COC)o2)cc1 +CC(=O)NC(C(=O)Nc1ccc(C(N)=O)c(Cl)c1)C(C)C +Cc1nnc(CN(C)C2CCN(C(C(N)=O)c3ccccc3)C2)n1C +Cn1cc(S(=O)(=O)NCCNC(=O)CC2CCCCC2)cn1 +COc1ccc(C(=O)N2CCC3(CC2)CC(OC)CO3)cc1F +O=C(NCC1CCC(CNC(=O)C2CC=CC2)CC1)C1CC=CC1 +CCOc1ccc(OCC(=O)Nc2ccc(N)nc2C)cc1 +Cc1ccc(C(NC(=O)c2n[nH]c(=O)[nH]2)c2ccccc2)cc1C +Oc1cc2c(cc1F)CCNC2c1ccc2ccccc2n1 +Cc1cccc(NC(=O)c2ccc(CNC(N)=O)cc2)c1C +CCS(=O)(=O)c1ccc(NC(=O)c2cnc3ccc(C)cn23)cc1 +CCN(C(=O)c1csnc1C)C(c1cccnc1)C(C)C +CC(CC1CCCC1)C(=O)Nc1cc(C(F)(F)F)c[nH]c1=O +NC(=O)Cc1csc(NC(=O)Cc2ccc(F)c(F)c2)n1 +CCC(Nc1ncnc(C)c1C)c1ccc(C)cn1 +CN(Cc1cc(C2CC2)[nH]n1)C(=O)C(c1cccc(F)c1)N(C)C +CC(C)(C)C(=O)NC1CC(=O)N(Cc2ccc(F)cc2)C1 +CCC(C)C(=O)Nc1ccccc1C(=O)N1CCOCC1 +CC(NC(=O)C(C)(C)C)C(=O)NCc1cn[nH]c1 +Oc1ccc2c(c1)C(C(O)c1ccccc1)NCC2 +O=C(c1cc(=O)[nH]c2ccccc12)N1CCCSc2ccccc21 +CCCC(=O)Nc1cc(S(=O)(=O)NC(C)(C)C)c(F)cc1F +CC(C)C(=O)N1CCC(NC(=O)Nc2ccc(Cl)cc2)CC1 +C#CCNS(=O)(=O)c1ccc(C(=O)N2CCCC2)cc1 +O=C1CC(C(=O)NCC2CC2)C(C(=O)NCC2CC2)C1 +Cn1c(C(F)(F)F)nn(CCNC(=O)c2ccc(C#N)cc2)c1=O +CCc1ccc(N(CC(=O)OC)S(C)(=O)=O)cc1 +CN(CC(=O)Nc1ccccc1)C(=O)c1cnns1 +CCN(CCO)C(=O)COc1ccc2ccc(=O)oc2c1 +CCC(C)NC(=O)c1ccc(-c2ccccc2)nc1 +CCN1CCN(C(=O)CCC2CCN(C(=O)COC)CC2)CC1 +COc1ccc(OCC(=O)OCC(=O)N2CCCCCC2)cc1 +C=CCNC(=O)CSc1c(C)cnc2c1c(=O)n(C)c(=O)n2C +O=C(CCn1ccccc1=O)OCc1nc2ccccc2s1 +NC(=O)CCC1CCCN(C(=O)c2ccc(-n3ccnn3)cc2)C1 +Cc1cc(C)n(CCNC(=O)CCc2[nH]nc3c2CCCC3)c(=O)n1 +CN(C)C(=O)Cn1cc(NC(=O)COc2ccccc2F)cn1 +C#CC1CCCCC1NC(=O)Nc1cnccc1C(F)(F)F +CCn1cc(NC(=O)CCc2nnc(-c3cc(C)nn3C)o2)cn1 +CCC(NC(=O)C1Cc2ccccc2C(=O)O1)c1ccc(OC)cc1 +O=S(=O)(NCc1ccccc1)c1ccc(CO)cc1 +O=C(Nc1ccc(-n2cncn2)nc1)C(c1ccccc1)N1CCCC1 +Cc1cc(CNC(=O)NCc2cccc(N3CCCCC3=O)c2)no1 +CCCc1nnc(NC(=O)CSc2nnnn2C2CC2)s1 +OC1=Nc2c(cnn2C2CCCC2)C(c2cccnc2)C1 +Cc1nc(SCC(=O)c2cc(C)n(C3CC3)c2C)nc(C)c1C +Cc1cccc(NC(=O)COc2cccc3cccnc23)c1 +COCC1CC2(CCN(C(=O)Cc3ccccc3C)CC2)CO1 +CCOc1ncccc1CNC(=O)c1sccc1C +CC(=O)C(C)(C)c1ccc2c(c1)N(C)C(=O)CCO2 +CC(=O)N1CCC(NC(=O)c2ccc3ccccc3c2)CC1 +Cc1ccc(C(=O)NCCNC(=O)Cc2ccc(F)cc2)cc1F +CC(C)(C)OC(=O)N1CC(NCc2ccncc2)C1 +CNC(=O)c1ccc(C2NC(=O)C3CCCCN32)cc1 +CC(CC(=O)N1CCN(c2ccc(F)cc2)CC1)C(N)=O +COc1cc(C)c(Cl)c(C)c1-c1cnnc(N)n1 +Cc1sc(=O)n(CC(=O)Nc2cccc(-c3nncn3C)c2)c1C +CCCCNC(=O)Cc1csc(-c2cccc(N)c2)n1 +CCN1CC(C(=O)OCc2ccc3cc(OC)ccc3c2)CC1=O +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)N1CCCCC1C +C#CCNC(=O)CSc1ncnc2scc(-c3ccccc3)c12 +O=S(=O)(CCC1CCCO1)NCCc1cccc2cccnc12 +COc1ccc(F)cc1NC(=O)CNC(=O)c1cccc(F)c1 +CC(C)n1ncc2c1N=C(O)CC21C(=O)N(C)c2ccccc21 +Cc1cccc(C(=O)Nc2ccc(C(N)=O)cc2)n1 +Cc1cccn(CC(=O)Nc2ccccc2C(=O)C(C)C)c1=O +COCCOc1c(Cl)cccc1NC(=O)c1ccsc1 +Cn1cc(CNc2ccc(S(C)(=O)=O)nc2)nn1 +CS(=O)(=O)NCCNC(=O)Cc1c(Cl)cccc1Cl +CCc1c(C(=O)Nc2ccc3c(c2)OCO3)[nH]c(C)c1C(C)=O +O=C(Nc1ccc(OCC2CCCO2)cc1)c1cccc2cccnc12 +COCCN1CC2CC(C(=O)Nc3ccc4c(c3)OCO4)C(C1)O2 +Cc1cc(C)c(NC(=O)COC(=O)CC2CCCC2)c(C)c1 +CC(C)(C)S(=O)(=O)c1cnc2c(-c3cccs3)cnn2c1N +NC(=O)COC(=O)Cc1ccc(-n2cnnn2)cc1 +Cc1occc1-c1nnc(SC2CCOC2=O)o1 +Cc1ccc(F)cc1CC(=O)NCc1csc(-c2cnccn2)n1 +CCCn1ncc(-c2ccc(F)c(F)c2)c(CO)c1=O +CS(=O)(=O)c1ccc(CNC(=O)Nc2cccc(F)c2F)cc1 +Cc1ccc(S(N)(=O)=O)c(C)c1-n1cnnn1 +CCC(c1nc(C(C)C)nn1-c1ccncc1C)n1cccn1 +COC(=O)c1nn(C)c(C)c1NC(=O)c1ccco1 +Cc1ccc2cc(-c3cnn(CC(=O)Nc4cnn(C)n4)c3)ccc2n1 +CCS(=O)(=O)NC1CCSc2ccc(F)cc21 +CCOC(C)C(=O)N(Cc1cccnc1)Cc1ccco1 +CC(C)OC(=O)Cn1c(CCCO)nc2ccccc21 +COCCn1cc(NC(=O)Nc2ccccc2F)c2ccccc21 +COc1ccc(C(=O)NCc2ccccc2F)c(N)c1 +COc1ccc(-c2noc(-c3cccn3C)n2)c(OC)c1 +CC1(NC(=O)Nc2ccccc2-c2ccncc2)CCOCC1 +CCCNC(=O)CSc1ccc(NC(C)=O)nn1 +Cc1cc(NC(=O)NCCNC(=O)c2cccnc2)n(C(C)C)n1 +CCCCc1nc(CN2CCc3ncnc(OC)c3C2)cs1 +CCc1onc(C)c1NC(=O)NC(C)(C)c1ncc(C)s1 +CC(CCc1ccccc1F)C(=O)Nc1nccn(C)c1=O +Cc1ccc(C(=O)CCC(=O)NCc2ccccc2)cc1N +CC(C)(CNC(=O)Nc1ccc(F)c(C#N)c1)N1CCOCC1 +COc1cccc(OCC(=O)Nc2cc(N3CCOCC3)ncn2)c1 +CN(C)C(=O)c1cccc(CN2CCCSc3ccccc32)c1 +CN(C)C(=O)C(O)c1ccc2oc(=O)n(C)c2c1 +Cn1ncc(NC2CCc3ccccc3C2)c(Cl)c1=O +CCC1CN(C(=O)Nc2ccccc2CC(N)=O)CCO1 +CNc1nc2c(c(=O)[nH]c(=O)n2C)n1Cc1cccc(C)c1 +COc1ccnc(NC(=O)CCCNC(=O)c2ccccc2)c1 +O=C(N1CCC(c2nc3ccccc3o2)CC1)C1(O)CCCC1 +C#Cc1cccc(N(Cc2cccs2)C(=O)C2COCCO2)c1 +CCc1cccc(C)c1NC(=O)c1ccc2c(c1)CCN2C(C)=O +CCn1c(=O)n(CCC(=O)N2CCNC(=O)CC2)c2ccccc21 +O=C(C1CC(=O)N(C2CCCC2)C1)N1CCN(c2ccccc2)CC1 +COc1ccc(C(CC(=O)Nc2ccccc2C#N)NC(C)=O)cc1 +Cc1ccc(NC(=O)C2CC(=O)N=C(Nc3ccccc3)N2)cc1 +CNc1nnc(SCC(=O)Nc2ccc(F)cc2)s1 +Cc1cc(SC(C)C(=O)N2CCOCC2)nc2ccccc12 +Cc1cc2cc(C(=O)N3CCCC3CO)oc2cc1C +COCC(=O)NCc1cn(-c2ccccc2)nc1-c1ccc(F)cc1 +COC(=O)CCn1c(-c2cccc(N)c2)nc2ccccc21 +COc1ccc(CC(C#N)C(=O)Nc2ccccc2)c(OC)c1 +Cc1[nH]ncc1S(=O)(=O)N1CCc2ccccc21 +Cc1cc(NC(=O)C(C)Sc2ccc(Cl)cc2)n(C)n1 +CC(Nc1nccc(C(F)(F)F)n1)c1ccncn1 +O=C1C(=O)N(Cc2ccccn2)c2ccc(F)cc21 +CN(C)c1ncc(Br)cc1C(=O)Nc1cnn(C)c1 +OC1CCC(Nc2ncc(Br)c3ccccc23)CC1 +CC(C)CNC(=O)c1nn(C)c2ccc(F)cc2c1=O +CCOC(=O)C1CCN(C(=O)Nc2cccc(OC)c2)CC1 +Cc1noc(C)c1CC(=O)Nc1cccc(Cn2cccn2)c1 +O=C(CC(C1CC1)C1CC1)N1CCC(Nc2cccnn2)CC1 +COc1ccccc1-c1nc(-c2ccncc2)no1 +O=C(COc1ccc2ccc(=O)oc2c1)NCc1cscn1 +Cc1ccc(Cc2nc3sc4c(c3c(=O)[nH]2)CCC(C)C4)cn1 +COC(=O)NCC(=O)Nc1nnc(CC(C)C)s1 +COC(=O)Cc1cn(S(=O)(=O)c2ccc(C)cc2)c2ncccc12 +Cc1ccccc1-c1nnn(CC(=O)N(CC(C)C)C2CC2)n1 +CC(C)(C)C(=O)C(Oc1ccc(Cl)cc1)n1cncn1 +CCn1cc(C(=O)Nc2ccc(-c3nnnn3C3CC3)cc2)cn1 +O=C(N1CCN(CC2COCCO2)CC1)C1(c2ccc(F)cc2)CC1 +N#Cc1ccc(CNC(c2ccc(Cl)cc2)c2ncon2)cc1 +O=C(Cc1cccc2ccccc12)Nc1ccn(Cc2ccncc2)n1 +COc1cccc(C=Cc2nnc3c(N)cc(C)cn23)c1 +CSc1ccc(C(=O)C(O)c2ccc(SC)cc2)cc1 +CC(C)C(=O)N1CCCC1C(=O)OCCCc1cccnc1 +Cc1nc(N2CCN(C(=O)C3CC=CCC3)CC2)c2cnn(C)c2n1 +O=C(CC1OCCc2ccccc21)Nc1ccc(-c2nnco2)cc1 +CCCn1nc(C)nc1-c1cc(-c2ccccc2)n[nH]1 +Cn1ccc(C(=O)N2CCCCC2c2cc(CCO)[nH]n2)n1 +CCCCNc1nnc(-c2sc(C3CC3)nc2C)s1 +Cc1cccc(OCCNC(=O)Nc2ccnn2C(C)C)c1 +CC(=O)c1ccccc1NC(=O)Cc1ccccc1 +Cc1cc(=O)oc2cc(OC(=O)c3ccoc3)ccc12 +CC(CNC(=O)c1cccc(Nc2ncccn2)c1)N1CCOCC1 +Cc1noc(C)c1CC(=O)Nc1ccc(-c2nccs2)cc1 +OC(COc1ccccc1C(F)(F)F)Cn1cccn1 +CN(Cc1ccccn1)C(=O)Cn1ccc(=O)[nH]c1=O +CCC(C)N(C)C(=O)c1cccc(CN2CCCC2=O)c1 +Cc1cc(Cl)ccc1S(=O)(=O)Oc1cccc(C(N)=O)c1 +CCN(Cc1ccc(C#N)cc1F)C(=O)Nc1cnn(CC)c1 +CC#CC(=O)N1CCc2[nH]nc(-c3ccc4c(c3)OCO4)c2C1 +Cc1sc(CNC(=O)N2CCC(C#N)CC2)nc1-c1ccccc1 +Cc1csc(CCCNc2nccc(-c3cccnc3)n2)n1 +CCCn1nc(-c2ccc(C)c(Cl)c2)cc(CO)c1=O +O=C(C1CCOCC1)N1CCC(OCc2cccnc2)CC1 +CS(=O)(=O)c1ccc(-c2noc(CCc3cccc(F)c3)n2)cc1 +CC(=O)N1CCC(C(=O)Oc2ccc(-c3ccc(C#N)cc3)cc2)C1 +CCOC(=O)c1ccc2cc3c(cc2c1O)OCCO3 +CCN(CC)S(=O)(=O)c1c(C)nn(Cc2nc(C)c(C)o2)c1C +COCC(C)N1CCN(C(=O)c2cc(NC(C)=O)ccc2F)CC1 +CCOc1ccc(C(=O)Nc2ncccc2O)cc1OCC +NC(=O)c1ccc(CNCCc2ccccc2F)s1 +CCS(=O)(=O)c1cccc(C(=O)Nc2onc3c2CCCC3)c1 +Cn1c(SCc2ccc(Cl)cc2)nc2c(=O)[nH]cnc21 +CC(NC(=O)c1ccccc1Cl)c1ccccn1 +Cc1ccc2c(c1C)OCC(O)C2N1CCN(CCO)CC1 +CC(C)COC(=O)C1CCCN1C1=NS(=O)(=O)c2ccccc21 +O=C(CCSc1ccccn1)Nc1ccncc1 +CCOc1ccc(F)c(C(=O)Nc2ccc(C(N)=O)c(C)c2)c1F +CCc1cc(=O)[nH]c2cc(NC(=O)c3ccc(=O)n(C)n3)ccc12 +Cc1ccc(S(=O)(=O)Nc2ccc3c(c2)C(=O)NCCO3)cc1 +CN1CCN(C(=O)CCCc2nc3ccccc3s2)CC1=O +CC1Oc2ccccc2N(CCC(=O)Nc2ccccc2C#N)C1=O +O=C(c1cc(=O)c2ccccc2o1)N1CCOC2CCCCC21 +CNC(=O)Cn1ccc2ccc(NC(=O)N(C)C(C)CC#N)cc21 +CC1CCCC(Nc2cccc(S(C)(=O)=O)c2)C1 +CC(=O)c1c(F)cccc1Oc1ccccc1C(N)=O +C=CCNC(=O)c1cn(-c2ccccc2)nc1-c1ccccc1 +COCCN(C)c1ccc2ccc(C(=O)N3CC(C)OC(C)C3)cn12 +C#CCN1CCN(CC(=O)N(C)CC2CCCCC2)CC1 +Cc1ccc(N2CC(C(=O)N3CCN(CCO)CC3)CC2=O)cc1 +COCC(=O)N1CCCC(C(=O)N2Cc3nc(C)n(C)c(=O)c3C2)C1 +COc1ccc(NC(=O)CN2CC(C)(C)Oc3ccc(N)cc32)cc1 +Cc1cccnc1CNC(=O)N(C)CCN(C)C(=O)OC(C)(C)C +CC1(C(=O)Nc2ccc3c(c2)OCO3)CC1(Cl)Cl +Fc1ccc(N2CCN(Cc3noc(C4CC4)n3)CC2)cc1 +Cc1ccsc1-c1nc(-c2ccc(NS(C)(=O)=O)cc2)no1 +COC(=O)c1ccc(F)c(S(=O)(=O)Nc2c(C)n[nH]c2C)c1 +O=C(CC1(Cn2cnnn2)CCCCC1)NCC1CCCO1 +CCC(=O)NCC(=O)Nc1cc(F)ccc1OC +Cc1nnnn1-c1cccc(C(=O)NCCc2ccncc2)c1 +O=C(CN1CCN(c2ccc(F)cc2)C1=O)N1CCCC1 +COC(=O)c1cccc2nc(C(F)(F)F)n(C)c12 +CCN(C(=O)CS(=O)(=O)c1ccc(Br)cc1)C1CC1 +Cc1nc(Cc2noc(CC3CC4CCC3C4)n2)no1 +Cc1cnc(C(=O)NC(C)c2cc(C)oc2C)cn1 +CCC(CC)C(=O)N(C)CCc1noc(-c2ccccc2F)n1 +NC(=O)C(Cc1ccccc1)NC(=O)c1ccc2c(c1)OCO2 +COc1ccc(C(NC(=O)C2CCNC(=O)C2)C2CCOCC2)cc1 +NC(=O)c1c(Cl)cccc1NC(=O)Cc1cccc(F)c1F +Cn1nnc2cc(C(=O)Nc3ccc(Cl)cc3)ccc21 +CN(Cc1ccsc1)C(=O)c1cn(C)c2ccccc12 +CN(C(=O)c1cnc(C2CCCO2)s1)c1ccc(Cl)cn1 +NC(=O)C1(CCCc2ccccn2)CCCN(c2ncccn2)C1 +Cc1cc(Sc2ncccn2)ccc1NC(=O)NCC1CCCO1 +Cc1ccsc1CN(C)C(=O)c1ccc2c(c1)NC(=O)CS2 +CN(C(=O)CC1CCCC1)c1nc2ccccc2o1 +CN(CCCNC(=O)N1CCCC(O)C1)c1ccccc1 +O=C(CNC(=O)c1cc2ccccc2[nH]1)NCC#Cc1ccccc1 +C=CCn1cc(CNC(CC)c2nc(C)no2)c(C)n1 +CN1CCN(Cc2ccc(C#CCO)s2)C(=O)C1=O +COc1ccc(NC(=O)COc2ccccc2Cl)cc1N +CCOc1ccccc1CN(C)c1nc(C)cc(C)c1C#N +O=C(Cn1cnnn1)NC(c1ccc2c(c1)OCCO2)C1CC1 +Nc1cc(C2CCN(S(=O)(=O)c3cccc(F)c3)CC2)no1 +NC(=O)CC1CCN(C(=O)C2(c3ccc(Cl)cc3)CCCC2)CC1 +Cc1nc2ccccc2n1CCNC(=O)NC1CCCCCC1 +COCC(C)COCc1ccc(Br)cc1 +COCC1CCCN1C(=O)Nc1cccc(-c2ccn[nH]2)c1 +Fc1cc(NCc2cccs2)ccc1-n1cncn1 +O=C(c1cnc2ccc(Br)cn2c1=O)N1CC(O)C1 +Cc1cc(CC(=O)N2CCN(C(C)c3ccccc3F)CC2)no1 +CC(C)Cc1cc(C(=O)N2CCC(C#N)(c3ccccc3)CC2)[nH]n1 +Cc1cc(Br)ccc1NC(=O)c1ccc(N)nn1 +Cc1c(C)n(CCc2ccccc2)c2ncnc(N3CCOCC3)c12 +C=CCNC(=O)CC(C)CC(=O)N1CCN(c2ccccc2F)CC1 +O=C(NCc1ncc(-c2ccccc2)o1)c1cc2ccccc2[nH]1 +COc1cccc(-n2nnc(C(=O)OC3CCCCC3)c2N)c1 +CCOC(=O)c1nc(NC(=O)c2ccc(Cl)cc2)sc1C +c1coc(CCc2nc3sc4c(n3n2)CCNC4)c1 +COc1ccccc1C(C)NC(=O)Nc1cc(C)on1 +CCn1ncc(C2CC(O)=Nc3c2c(=O)[nH]n3C(C)C)c1C +O=C(CSc1nnnn1C1CC1)NCC1CC=CCC1 +CN1CC(Cc2ccccc2F)Oc2cc(O)ccc21 +COc1ccccc1CC(=O)Nc1cc(=O)oc2ccccc12 +CCN(CC)C(=O)c1cc(N)n(-c2ccc(Cl)cc2)n1 +O=C(C1CCC1)N1CCN(c2ncc(C(F)(F)F)cc2Cl)CC1 +O=C(NCc1ccsc1)Nc1ccc(-n2cncn2)c(F)c1 +N#CCCN(CCN1CCOCC1)C(=O)c1csc2c1CCCC2 +O=C(NCC1CCCCC1)c1noc(-c2ccc[nH]c2=O)n1 +CC(C)Sc1ccccc1NC(=O)NC1CCc2ncnn2C1 +Cc1ccc(-c2cc(C(F)F)n3ncc(C#N)c3n2)s1 +O=C(NCc1ccc(N2CCCC2=O)cc1)N1CCc2ccccc2C1 +COCCCN(C)C(=O)CNC(=O)c1ccc(F)c(F)c1 +Cc1cccc(CN2CCC(c3cc(=O)[nH]c(C)n3)C2)n1 +Cc1cc(N)nn1CC(=O)NCCn1ccc(C2CC2)n1 +N#Cc1ccc(CN2CCN(S(=O)(=O)c3cccnc3)CC2)cc1 +CCSc1ccccc1C(=O)Nc1nc(-c2ccncc2)cs1 +CN(Cc1ccsc1)C(=O)c1cc(Br)ccc1O +CCS(=O)(=O)N1CCN(CCNC(=O)C2CCCC2)CC1 +Cc1ccc(C(=O)N(CC(F)(F)F)C2CC2)c(O)c1 +Cc1cnc2c(C(=O)NC(C)c3nncn3C(C)C)cnn2c1 +Cc1sc(=O)n(CC(=O)NCC(=O)Nc2ccccc2)c1C +Cc1nc(CN2CCN(Cc3cc4ccccc4s3)CC2)no1 +Cc1csc(CCNC(=O)c2cccc(Br)c2)n1 +CC(=O)NCc1ccc(-c2nc3ccc(C)cc3o2)cc1 +CC(C)(CNC(=O)CCC1CCCC1)N1CCOCC1 +NC(=O)c1ccc(NC(=O)Cc2ccc3c(c2)CCCC3)cc1 +CN(Cc1nccs1)Cc1cc(C(F)(F)F)ccc1F +COc1ccc(CN2CC(C(=O)C(C#N)c3ccccn3)CC2=O)cc1 +Cc1csc(CNC(=O)N2CCN(c3cnccn3)CC2)n1 +Cc1ccoc1C(=O)NCCCNc1cccc(-n2ccnc2)n1 +C=CC(=C(CO)c1ccccc1)n1nnc2ccccc21 +NC(=O)c1ccc(Cl)cc1NCC(=O)N1CCc2ccccc2C1 +NC(=O)c1ccsc1NC(=O)c1ccccc1F +COc1ccc(-c2csc(CNC(=O)C3CCC3)n2)cc1 +CNC(=O)CCN1CCN(C(=O)CCC(C)C)CC1 +Cc1cc(C(=O)N(CCC(N)=O)Cc2ccccc2)c(C)n1C1CC1 +Cc1nn2cnnc2c(C)c1CCC(=O)Nc1ccc(CC#N)cc1 +O=C(NCc1ccc(C(F)(F)F)cc1)c1nc2ccccc2c(=O)[nH]1 +Cc1ccc(OCC#CCNC(=O)c2ccccn2)cn1 +CCCC(C)C(=O)OCC(=O)N1CCCCCC1 +Cc1sc(C(=O)N(C)S(C)(=O)=O)cc1-c1ccc(F)cc1 +CN1CCN(S(=O)(=O)Cc2ccccc2Cl)CC1 +Cc1ccnc(OCCCC2CCCN(C(=O)OC(C)(C)C)C2)n1 +Oc1cccc(NCc2ccc(Br)cc2)c1 +CCCC(=O)Nc1ccc2c(c1)nc(CCn1ccccc1=O)n2C +CC(C)CC(=O)Nc1nn(C)c2c1CC(C)C(=O)N2 +CN(C(=O)c1cccs1)C(C#N)c1cccc(Cl)c1 +CC(=O)NCC(=O)NCC1(c2ccc(F)cc2)CCOCC1 +O=C(c1scnc1C1CC1)N1CCOc2cccc(F)c21 +Cc1cc(CNC(=O)CCc2cnn(C)c2)c(C)o1 +Cc1cc(CC(=O)Nc2ccccc2Sc2c(C)n[nH]c2C)on1 +Cn1cnnc1-c1ccccc1NS(=O)(=O)N1CCCCCC1 +CCOC(=O)CN(CC)C(=O)CN1CCCC1=O +Cc1ccc(C(=O)NCc2c(C)nc3cc(=O)[nH]n3c2C)c(=O)[nH]1 +Cc1cccc(OCC(=O)N2CCNC(=O)C2)c1C +O=S(=O)(c1ccccc1)N1CC(OCc2cccc(F)c2)C1 +CSc1nsc(NC(=O)c2cccc(NC(C)=O)c2)n1 +Cc1ccc(C(C)(C)CNC(=O)CCNS(C)(=O)=O)cc1 +CCOC(=O)C1C(C)N=C(CN2CCCCC2)C1C +CC(Oc1ccc(F)cc1F)C(=O)N1CCN(c2ncccn2)CC1 +CC(=O)N1c2ccccc2NCC1c1ccccc1 +CNC(=O)c1ccc(C=Cc2nc(C(C)(C)OC)no2)cc1 +CC(=O)N1c2ccccc2C(CSc2nnc(C)s2)=CC1(C)C +N#Cc1ccc(OCC(=O)OCc2nccs2)cc1 +Cc1cc(C(C)(C)C)oc1C(=O)NC(C)Cn1cncn1 +CNC(=O)COc1ccc(CNc2c(F)cc(C#N)cc2F)cc1 +O=C(NCC#Cc1ccccc1F)c1ccc(F)c(F)c1 +CN(CCc1ccccn1)C(=O)CCc1c[nH]c2ccccc12 +Cc1ccncc1NC(=O)N1CCCN(CC(F)(F)F)CC1 +Cc1ccc(NC(=O)NCCc2nnc3ccccn23)cc1Cl +CCCNC(=O)C(C)OC(=O)c1ccc(OC)c(F)c1 +N#Cc1ccc(Oc2ccc(Br)cc2F)nc1 +Cc1cccc(OC(=O)C(C)NC(=O)c2cccs2)c1C +O=C(CNc1ccc(C(=O)N2CCCC2)cc1)NC1CC1 +O=C(NCCS(=O)(=O)c1ccccc1)NCc1ccc(F)cc1 +CCCS(=O)(=O)N(C)C(C#N)c1cc(OC)ccc1OC +CC(C)CN(c1ccc(S(N)(=O)=O)cc1N)C1CC1 +CS(=O)(=O)NC1CCN(C(=O)c2ccc3c(c2)OCCO3)CC1 +Cc1cc(N2CC(S(=O)(=O)NC3CCCC3)C2)n2ncnc2n1 +Cn1cc(CNC(=O)Nc2ccccc2OCCC(N)=O)cn1 +N#Cc1cccc(OCCN2CCOC(Cn3cccn3)C2)c1 +O=C(OCc1ccc(C(=O)N2CCCC2)cc1)c1cc(Cl)c[nH]1 +O=C(CSc1nnc(-c2ccccc2)o1)NCc1ccccc1F +N#CCCCSc1nc(=O)c2ccsc2[nH]1 +O=S(=O)(Cc1c(Cl)cccc1Cl)c1ccc(O)cc1 +O=C1CC(C(=O)N2CCCC2c2ccncc2)CN1CC1CC1 +Cc1nc(C(F)(F)F)ccc1C(=O)Nc1ccc(-n2ccnc2)nc1 +NC(=O)CCN(Cc1ccccc1)Cc1ccccc1Cl +COc1ccccc1C1NCCc2c(OC)cccc21 +Cc1nnc2n1CCN(Cc1cc(Cl)c3c(c1)OCCCO3)C2 +COc1ccccc1Nc1nnc(Sc2nccnc2C#N)s1 +COc1ccc2nc(N(CCC#N)CCC#N)sc2c1 +Cc1cc(F)ccc1NC(=O)NCCS(=O)(=O)NCC1CCC1 +CCOc1cc(NC(=O)NCc2ccc(C)c(F)c2)ccc1OC +O=C(Oc1ccc(N2CCOC2=O)cc1)c1scnc1C1CC1 +Cc1nn(C)c2ncc(SC(=O)N(C)C)cc12 +Cc1ccoc1-c1nnc(Cn2cnc3c(oc4ccccc43)c2=O)o1 +Cc1nnc(SCc2c(C(=O)NC(C)C)oc3ccccc23)s1 +Cc1cc(C)nc(SCC(=O)N2CC(=O)Nc3ccccc32)n1 +Cc1csc(N2CCN(C(=O)CCc3nccs3)CC2)n1 +COCC(=O)Nc1cc(C)n2nc(C(F)(F)F)nc2n1 +O=C(NCCOc1cccc(Cl)c1Cl)c1cnccn1 +Cc1ccc(C=CCC(=O)NC(c2nnc3n2CCC3)C(C)C)cc1 +CCc1ccc(C(=O)Nc2ccc(C(=O)NC(C)C)c(C)c2)o1 +N#Cc1c2n(c(=O)n(CC(=O)N3CCCC3)c1=O)CCC2 +O=C(CN1CCc2ccccc21)Nc1ccc(Br)cn1 +CCC1CCCCC1NC(=O)NCCNC(=O)c1ccccc1 +Cc1cc(NC(=O)c2ccc(C)s2)n(-c2ccccn2)n1 +N#Cc1c(NC(=O)c2ccno2)sc2c1CCC2 +Cc1cnc(C(=O)Nc2nc3ccc(Cl)cc3s2)cn1 +Cc1nnc(NC(=O)NCCCN2CCc3ccccc32)s1 +Cc1nn2ncc(C(=O)NCCc3cccc(-c4ccccc4)c3)c2[nH]1 +Cn1cnc(CNC(=O)NC(c2ccccc2)c2cccc(F)c2)n1 +O=C(Oc1ccc2c(c1)OCO2)c1ccc(-n2ccnn2)cc1 +NC(=O)CCN1C(=O)CNc2cc(Cl)ccc21 +CC1Cc2cc(C(=O)NCc3ccncc3)ccc2N1S(C)(=O)=O +CCN1C(=O)Cc2ccccc2C1C(=O)N1CCOCC1 +O=C(CCNC(=O)c1ccc(Cl)cc1Cl)Nc1ccccc1 +COCC(=O)NC1(c2cccc(Br)c2)CCOCC1 +COCC1c2nnn(C)c2CCN1C(=O)c1nn(C)c2ccccc12 +COc1ccc(S(=O)(=O)NCC(C)C)cc1NC(C)=O +CCOc1ccc(NC(=O)C2CCCN(S(C)(=O)=O)C2)cc1F +COC(=O)c1cnc(NC(=O)c2ccccc2F)s1 +C#CCN1CCN(C(C)C(=O)Nc2nc(C)c(C)s2)CC1 +N#Cc1c(-c2cccs2)nc2sc(C3CCCO3)nn12 +Cc1nn(C)c2cn(C(C)C(=O)NCc3ccncc3)nc12 +CCCCc1ccc(NC(=O)c2ccc(=O)n(C)n2)cc1 +CCC(=O)N1CC(C(C)C)Oc2ccc(C(C)=O)cc21 +Cn1cc(C2CC2C(=O)N2CCCN(c3ccccc3C#N)CC2)cn1 +CCc1ccc(CC2Oc3ccc(N)cc3NC2=O)cc1 +CC(c1cc(F)ccc1F)N(C)C(=O)CSc1nncs1 +O=C(Nc1ccccc1-n1cnnn1)C1CCCC1 +CCc1ccc(-c2nc3sc(COC)nn3c2C#N)cc1 +COc1ccc(Nc2ccc(C#N)cn2)cc1N1CCCC1=O +CCCCN(C)c1ncc(C(=O)NCc2ccccc2)c(N)n1 +COc1ccc2[nH]c(-c3ccco3)c(C(C)=O)c2c1 +CCSc1nnc(NC(=O)c2n[nH]c(=O)c3ccccc23)s1 +CC(C)C(CC(=O)N1CCCN(C(N)=O)CC1)c1ccccc1 +CCc1onc(C)c1NC(=O)Cn1ccc2ccc(Cl)cc21 +O=c1[nH]c2ccsc2c(=O)n1C1CCCCC1 +O=C(c1cccc(Cl)c1)N(Cc1ccsc1)CC(F)(F)F +OC1(c2ccc(Cl)cc2)CCC2(CC1)OCCO2 +COc1cc(N)ccc1Oc1ccc(C#N)cc1F +COc1cccc(C(=O)OCCCc2cccc(C)n2)c1 +O=C(Nc1cccnc1)C1CCOC2CCN(c3ccncn3)CC21 +O=C(CSc1nc(Cc2ccccc2)n[nH]1)NC1CCCCC1 +CC(C)N1CC(C(=O)Oc2c(Cl)cccc2Cl)CC1=O +CC(O)CC(C)(C)CNC(=O)NCC1CCCCC1 +CC(C)COC1CCN(C(=O)c2csc(-c3ncccn3)n2)CC1 +Cc1c(NCc2nc(C3CC3)no2)cccc1N1CCCC1=O +Fc1ccc(N2CCN(c3nc4cccnc4s3)CC2)cc1 +CCc1nc(NC(=O)c2cnn(-c3ccccc3)n2)sc1C +CCCNC(=O)c1ccc(NC(=O)NCCC(=O)N2CCCC2)cc1 +Cc1noc(COC(=O)C(C)Cc2ccccc2F)n1 +Cn1nc(C(=O)NC2CC2)cc1OCC(=O)N1CCCC1 +COc1ccc(C(O)C2CCCN(C(=O)OC(C)(C)C)C2)cc1 +Cc1nc(C)c(-c2coc(N)c2C(=O)c2ccccn2)s1 +CC1(c2ccccc2)CCCN(Cc2cc[nH]n2)C1 +O=C(c1ccc[nH]1)N1CCC(O)(c2ccc(Cl)cc2)CC1 +COc1cc(C(=O)NCCc2ccc(F)cc2)ccc1OC(C)C +C=C(C)CN(CC)C(=O)NCc1ccc(CN2CCCC2=O)cc1 +Cc1ccc(NC(=O)C(C)S(=O)(=O)c2ccccc2F)c(F)c1 +N#CC(NC(=O)c1ncn(-c2ccccc2)n1)c1ccc(Cl)cc1 +Cn1cccc1C(=O)NCCc1cnn(-c2ccccc2)c1 +Fc1ccccc1-c1noc(NCCCN2CCOCC2)n1 +Cc1ccc(OCC(=O)Nc2ccc(-n3cnnn3)cc2)cc1C +COc1cc(C(=O)N2CCCC3(CCC(=O)N(CCO)C3)C2)ccn1 +COC(CNC(=O)COc1ccc(F)cc1)c1ccc(C)s1 +Cc1noc(CCC(=O)Nc2ccc3c(c2)CCC3)n1 +CC(C)Oc1ccc(-c2noc(C(=O)NCc3ccccn3)n2)cc1 +O=C(CS(=O)(=O)c1ccccc1)N1CCCC1 +O=C(Cc1ccc(Cl)cc1)N1CCc2c(nc[nH]c2=O)C1 +COc1cccc(-c2nc3cc(C)ccn3c2C#N)c1 +COc1cccc(C(=O)NC2CCSc3c(F)cccc32)c1O +CCOCCn1c(C(C)NC(=O)C2CC2)nc2ccccc21 +CC(C)C(=O)Nc1ccc(NCC(=O)N(C)c2ccccc2)cc1 +O=C(NC1CC1)c1cccc(N2CCCS2(=O)=O)c1 +CC(=O)Nc1cc(C(=O)Nc2ccc3c(c2)CC(=O)N3)ccc1C +Cn1c(-c2ccccc2)cnc1NCc1ccccc1F +COc1ncccc1NC(=O)CC1c2ccccc2C=CN1C(C)=O +COc1cc(F)c(S(=O)(=O)N2CCNC(=O)C2)cc1OC +CCc1onc(C)c1NC(=O)CCOc1ccccc1 +N#Cc1c(F)cccc1S(=O)(=O)N1CCNC(=O)C1 +Cc1ccc2[nH]nc(C(=O)N(C)Cc3ccc(C#N)cc3)c2c1 +CC(C)(C)OC(=O)NCC(c1cccc(F)c1)N1CCOCC1 +Cc1ccc(NS(=O)(=O)c2ccc3c(c2)NC(=O)CO3)c(C)c1 +O=C(NCCC1=CCOCC1)NCC(O)c1ccc(Cl)c(F)c1 +CCCn1cnnc1CN(C)C(=O)Cn1c(=O)cnc2ccccc21 +CNS(=O)(=O)c1ccc(CNC(=O)CCc2cccnc2)cc1 +CC(=O)NC(Cc1c[nH]c2cc(F)ccc12)C(=O)N1CCCC1(C)C +CCOC(=O)CN(C)C(=O)c1cc(Br)ccc1F +Cc1ccc(NC(=O)C(Nc2ccn(C)n2)c2ccccc2)cc1 +C=CCN(C(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1)C1CC1 +CC(C(N)=O)n1cc(-c2ccc(SCc3ccccc3)cc2)cn1 +O=C(Cc1ccc(Cl)cc1)N1CCCC1c1ccccn1 +COc1ccc(OCCC(=O)N2CCC(c3nc(C)no3)CC2)cc1 +CCOc1ncc(C(=O)N(c2cccnc2)C(C)C)cc1Cl +O=C(Nc1ccccc1)C1CCCN(C(=O)c2cscn2)C1 +COC(=O)CC(NC(=O)Nc1ccnn1C(C)C)c1cccs1 +CCOCCCNC(=O)c1csc2c1CCC(C)C2 +Cc1ccccc1Cn1ccnc1C(=O)N1CCN(C)CC1 +COC(=O)c1sc(NC(=O)c2ccc(F)cc2O)nc1C1CC1 +COc1ccc(CNC(=O)c2ccc3[nH]c(C(F)(F)F)nc3c2)cc1 +Cc1ccc(N2CCN(C(=O)C3CC3)C(C)C2=O)cc1Cl +CCN1C(=O)C(C)(C(=O)NCC(C)O)Sc2ccccc21 +O=C(COc1ccc(F)cc1)N1CCN(Cc2cccc(F)c2)CC1 +N#CC1(C(=O)Nc2ccc(OC3CCOC3)cc2)CCCCC1 +O=C(Cc1ccccc1F)Nc1c[nH]cc(Br)c1=O +COc1ccc(NC(=O)Nc2cnn(C)c2)cc1Cc1ccccc1 +CC(C)CC1(CNC(=O)Cn2ncc(=O)c3ccccc32)CCCC1 +Cc1ncsc1C(=O)NCCc1nc(-c2ccccc2)n[nH]1 +CCc1cc(C(=O)N2CCN(C(=O)Cn3cnnn3)CC2)[nH]n1 +O=C(NCC(=O)N(Cc1cc(F)ccc1F)c1ccccc1)C1CC1 +O=C(OCc1nnc(-c2ccccc2)o1)c1cccc(-n2cnnn2)c1 +COC(=O)C1CCCN1C(=O)Cn1c(C)c(C)sc1=O +COc1ccccc1C(C)CC(=O)Nc1ccc2c(c1)CC(=O)N2 +COCCCN(C)C(=O)C1CC1c1ccccc1F +CNC(=O)Cn1nnc(CO)c1-c1ccccc1Cl +COc1cccc(NC(=O)Oc2cccc3cccnc23)c1 +N#Cc1nnc2ccccc2c1N1CCC(C(N)=O)CC1 +COCCCN(C)C(=O)c1cc(Cl)ccc1F +O=C(NC1CC(=O)N(c2ccc(Cl)cc2)C1)C1CC1 +COc1ccc(C(=O)Nc2cc(C)c(C)cc2N)cc1 +N#CC(C(=O)C1CC1)c1nc(-c2ccc(Cl)cc2Cl)cs1 +O=C(NCc1cccnc1)C1CC1c1ccc(OC(F)(F)F)cc1 +CC(NC(=O)c1ccc(F)cc1N)c1ccncc1 +CSc1ccc(C(=O)Nc2ccccc2O)cc1 +CNc1snc(C)c1C(=O)OCc1cccc(OC)c1 +Cc1noc(C)c1C(=O)NC1CCSc2ccc(Cl)cc21 +CCOc1c(Cl)cccc1NC(=O)c1cccnc1 +COC(=O)c1sc(NC(=O)Cn2cc(C)cn2)cc1C +N#Cc1cnn(-c2ccccc2NS(=O)(=O)c2ccccc2)c1N +COC(=O)c1ccc2c(c1)CCN2C(=O)Cc1ccsc1 +Cc1ccc(CNc2nc(N(C)C)nc3c2cnn3C)cc1 +Cc1ccc(C(=O)Nc2ccccc2)cc1NC(=O)Nc1cnn(C)c1 +CCCc1nc(C2CCCO2)sc1-c1nnc(NC)s1 +COc1cc(C)c(C(=O)N2CCSc3ccccc32)cc1OC +Cc1ccc(NC(=O)N2CCCC(O)C2)cc1OCC(F)F +COC(=O)Nc1cccc(NC(=O)CCC(C)(C)C)c1 +NC(=O)COc1ccc(NC(=O)c2cnn(-c3ccccc3)c2)cc1 +Cc1ccc2c(CC(=O)NCCC3CCCO3)coc2c1C +Cc1nccc(CNC(=O)CCc2ccc(Br)cc2)n1 +Cc1c(Cl)cccc1NC1C(=O)Nc2ccccc21 +O=C(Cc1cn2ccccc2n1)NCC1CCCO1 +c1nc(NCc2noc(C3CCCC3)n2)c2nc[nH]c2n1 +CC(C(=O)Nc1ccc(C(=O)NC2CC2)cc1)c1cccs1 +CCCCCOCC(=O)Nc1ccc(C)cc1N +NC(=O)CNC(=O)c1ccc(-c2nc3ccccc3s2)s1 +Cc1c(NC(=O)Cn2cnnn2)cccc1OC1CCCC1 +CC(C)CC1COCCN1C(=O)c1cnc2sccn2c1=O +CC(C)(CNC(=O)NCCc1cn2ccccc2n1)N1CCOCC1 +Cc1cnc(N2CCOC3C(CNc4ncccn4)CCC32)nc1 +COc1ccccc1OC1CN(C(=O)c2cccc(C(C)=O)c2)C1 +Cn1c(C(F)(F)F)nc2c(Br)c(F)ccc21 +CCOC(=O)CCC(C)NC(=O)N1CCOC(c2ccco2)C1 +C=CCNC(=O)Cc1cn2cc(Br)ccc2n1 +C=CCNS(=O)(=O)c1ccc(C(=O)Nc2cccc(C)n2)cc1 +O=C(NCCNS(=O)(=O)c1cc(F)cc(F)c1)c1ccoc1 +COCCN(CC(C)C)C(=O)Nc1ccc2c(c1)CCC(=O)N2 +Cc1c(Cl)cccc1N1CC(C(=O)NCc2ccco2)CC1=O +Cc1cc(C(C)NC(=O)CSc2nncs2)c(C)o1 +CCOC(=O)C=C(Nc1ccc2nc[nH]c2c1)C(F)(F)F +O=C(NCCc1ccsc1)c1ccc(N2CCOCC2)nc1 +O=C(c1ccc2c(c1)OCO2)N(CCO)CCO +COc1ccc(C(C)Cn2cc[nH]c2=O)cc1OCC1CC1 +CNS(=O)(=O)c1ccc(NC(=O)c2cnc3ccc(C)cn23)cc1 +CC(C)c1ccc(NC(=O)CSc2n[nH]c(=O)n2C)cc1 +CCOC(=O)Cc1nnc(-c2ccc(Br)cc2)o1 +NS(=O)(=O)N1CCN(C2CCCc3ccccc32)CC1 +CC(C)(C)n1c(N)nc2cc(C(F)(F)F)ccc21 +CCOC(=O)Nc1nc2c(s1)CN(C(=O)Nc1ccccc1)CC2 +CCOC(=O)C1CCN(C(=O)Nc2ccc(-n3cnnn3)cc2)CC1 +CN(C(=O)Cn1nnc(-c2ccccc2)n1)C1CCCc2ccccc21 +N#Cc1c(F)cccc1NC(=O)Cn1ccc(N)n1 +CC(C)C(=O)NC1CCCN(C(=O)Cc2c(F)cccc2F)C1 +Cc1ccc(-n2c(=O)[nH]c3ccsc3c2=O)cc1 +N#CCOc1cccc(CC(=O)N2CCN(c3ncccn3)CC2)c1 +CCOC(=O)c1c(NC(=O)CC#N)sc(C(=O)N(C)C)c1C +COc1ccc(CNC(=O)Cn2cc(C#N)c3ccccc32)cc1 +CC(C)c1noc2ncc(C(=O)NCC3CCCO3)cc12 +Cc1n[nH]c(C)c1C(C)CC(=O)NCC1COC2(CCCCCC2)O1 +O=C(NCCNc1nc2ccccc2s1)c1cccs1 +CCc1ccc(CNC(=O)Cn2ccc3c(C)nn(C)c3c2=O)cc1 +CCCn1cnnc1CNc1cc(C)nc2c(C)c(C)nn12 +O=C(Nc1cc2ccccc2oc1=O)c1cc2n(n1)CCCO2 +CC(C)c1cc(C(=O)N2CCN(C(=O)c3ccncc3)CC2)on1 +N#CCn1c(-c2ccc3c(c2)OCO3)nc2ccccc21 +CC(C)(C)NC(=O)CSc1nc(-c2cccs2)ccc1C#N +Clc1ccc(-n2nnnc2SCCn2cccn2)cc1 +CCn1cc(C(=O)NCc2nnc(C(C)C)n2C)cn1 +CC(=O)Nc1ccc(Sc2c(F)cc(N)cc2F)cc1 +C=CCn1nnnc1SCCOc1ccccc1F +NC(=O)C1CN(Cc2nc3sc4c(c3c(=O)[nH]2)CCC4)CCO1 +CC(OCC1CCCO1)C(=O)NC1(C)Cc2ccccc2C1 +Cc1nn(C)c(C)c1CC(=O)OCc1nc(-c2ccc(F)cc2)no1 +COCCOc1ccccc1C(=O)Nc1cccc(-c2nnco2)c1 +COc1ccc(C)cc1NC(=O)Cn1ccc2ccccc2c1=O +O=C(Cc1cccc2ccccc12)NCC1CCCO1 +O=C(NCc1ccncc1)c1cc(Br)c[nH]1 +COCCN(CC(N)=O)S(=O)(=O)c1ccc(C#N)c(Cl)c1 +CCCNC(=O)CCCC(=O)c1ccc2c(c1)CCC2 +COc1ccc(-c2cn3cc(C#N)ccc3n2)cc1OC +COC(=O)c1cc(CNC(=O)Cc2cccc(OC)c2)oc1C +CC(C)NC(=O)CN(C)C(=O)c1cc(C2CC2)nn1-c1ccccc1 +O=C(COc1ccccn1)NCCc1ccc(F)cc1 +Cc1ccc2c(Nc3ccccc3)c(C(=O)N3CCCCC3)cnc2n1 +O=C1CCN(C(=O)Cc2ccc(Cl)cc2)CC1 +CN(Cc1nc2ccccc2[nH]1)C(=O)c1cc(Br)c[nH]1 +CC(=O)c1ccc(OCC(=O)c2c(C)[nH]c3ccccc23)cc1F +COc1ccc(-c2ccc3[nH]c(=O)[nH]c(=O)c3c2)cc1OC +CCc1ccc(NC(=O)CC(C#N)c2ccccn2)cc1 +CCC(CO)NC(=O)Nc1ccc(-c2nnnn2C2CC2)cc1 +O=C(Cc1noc(CCc2ccccc2Cl)n1)NC1CCCC1 +CC1Cc2ccccc2N1C(=O)COC(=O)c1ccn(C(C)C)n1 +COc1cc(OC)c(NC(=O)c2cc(C(C)C)[nH]n2)cc1F +Cc1ccccc1CNC(=O)CCc1nnc(-c2ccoc2C)o1 +CCc1cccc(C)c1NC(=O)c1cccc(S(C)(=O)=O)c1 +CC1CCCCN1C(=O)CCNC(=O)CC1CCOc2ccccc21 +O=C1Nc2ccccc2C1CNC=CC1=CCCCC1 +CS(=O)(=O)NCCC1CN(Cc2cc3ccccc3[nH]2)CCO1 +C=CCn1c(-c2ccccc2)cn2c3c(=O)n(C)c(=O)n(C)c3nc12 +CC(C)(C)c1nnc(NC(=O)c2csc(NC3CC3)n2)s1 +CC(C(=O)Nc1ccc(S(C)(=O)=O)cc1)c1cccs1 +COc1ccccc1CSc1nc2cccnc2n1C +Cc1ncnc2c1CN(C(=O)c1ccsc1)CC2 +COC(=O)c1cc(Cl)ccc1OCC(=O)N1CCOCC1 +COc1ncc(Cl)c(NC2CCCC2C(N)=O)n1 +O=C(Cn1ccccc1=O)NCc1ccccc1N1CCOCC1 +N#Cc1ccc(CNc2nc3[nH]cnc3c(=O)[nH]2)cc1 +COc1ccc(NC(C)=O)cc1NCC(=O)Nc1cc(C)on1 +CCOCCSc1nnc(N2CCOCC2)n1-c1ccccc1 +Cc1c(C(=O)Nc2cccc(F)c2)nnn1-c1ccc(Cl)cc1 +CCOC(=O)C(C#N)C1(CC)CCOC(C)(C)C1 +CCn1nc(C)c(CN2CCN(C(=O)c3cc(C)oc3C)CC2)c1C +Cc1c(CNC(=O)Nc2ccnc(Oc3ccccc3)c2)cnn1C +NC(=O)c1ccccc1NC(=O)C1CN(C(=O)c2cnccn2)C1 +Nc1c(S(=O)(=O)C2CC2)nsc1C(=O)NC1CC1 +Cn1ncc2c(N3CCN(C(=O)c4cccc(C#N)c4)CC3)ncnc21 +CCc1noc2ncnc(Nc3ccc4c(c3)OCCO4)c12 +NC(=O)c1ccc(NC(=O)c2scnc2C2CC2)cc1F +CC(Oc1ccc(Cl)c(Cl)c1)C(=O)NC1CC1 +CCC(C)Oc1ccc(-c2cc(CO)c(=O)n(CC)n2)cc1 +O=C(CNC(=O)c1ccsc1)Nc1ccnn1C1CCCCC1 +O=C(C1CCCO1)N1CCN(CCOc2ccccc2F)CC1 +Nc1cc(F)c2c(c1)NC(=O)C(c1ccc(F)cc1)O2 +O=C(NC1CCCCCC1)c1csc(-c2cnccn2)n1 +N#CCOc1cccc(CC(=O)NCCc2cc(F)ccc2F)c1 +CSc1nc(-c2ccco2)nc(C)c1C(=O)N1CCC(C)CC1 +Cc1ccccc1N1CCN(C(=O)CCc2nncn2C)C(C)C1 +Cc1nonc1C(=O)N1CCc2ncnc(NCC(O)CO)c2CC1 +Nc1ccc2c(c1)CCCN2C(=O)CCc1ccccc1F +Cc1ccc(C)c(NC(=O)N(C)Cc2nccn2C(F)F)c1 +CCCNC(=O)c1ccc(NC(=O)Cc2ccccc2C)cc1 +Cc1nccn1S(=O)(=O)c1ccc(Cl)cc1Cl +CC1(C)Oc2ccc(NC(=O)c3cccs3)cc2NC1=O +N#Cc1nn(Cc2ccncc2)c2c1C(=O)CCC2 +Cc1ccc2c(c1F)CCNC2c1cc[nH]c(=O)c1 +O=C(CSc1ccc2c(c1)CCC2)Nc1nc2ccccc2[nH]1 +Cc1c(N)cc(C(=O)N2CCCCCC2)cc1F +O=C(N1CCOCC1)N1CCCn2c(cc3ccccc32)C1 +CCC(C)Nc1nc(-c2c(C)cc(C)n(C)c2=O)cs1 +O=C(Cc1cccc(F)c1)NCc1ccc2c(c1)OCCCO2 +CC(=O)Nc1cc(C(=O)N2CCc3ccccc32)ccc1C +CN(C)c1ccc(C(=O)N2CCCC2c2ccc(Cl)cc2)nn1 +Cc1ccc2c(CC(=O)OCc3csc(C)n3)coc2c1 +CNS(=O)(=O)c1ccc(NC(=O)c2ccc3ccccc3c2)cc1 +Cc1ccc(CN2CC(C(=O)N(C)CCC(C)C)CC2=O)cc1 +O=C(CSc1nncs1)NCCC1=CCCCC1 +CSc1ncc2c(=O)oc(=O)n(C(C)C)c2n1 +Cc1ccc(C=Cc2nc(SCC(=O)c3ccc(F)cc3)n[nH]2)o1 +Cc1c(OCC(=O)N(C)C)ccc2c3c(c(=O)oc12)CCCCC3 +CC(O)CNc1ccc(S(=O)(=O)N2CCCC2)cn1 +CCCS(=O)(=O)N1CCC(NC(=O)NC2CCCCC2)CC1 +Cc1cc(C(=O)N2CCOc3ncccc32)c2c(C)noc2n1 +O=C(CCc1nc2ccccc2[nH]c1=O)NCCC1C=CCCC1 +CN(Cc1cc2c(cc1OC(F)F)OCO2)C(=O)Cc1ccc[nH]1 +O=C(c1cc(-c2cccc(F)c2)no1)N1CCOC2CCCCC21 +CC(=O)c1c(C)[nH]c(C(=O)CN2CCOC(C)(C)C2)c1C +COC1CCCCC1NS(=O)(=O)c1cc(C)c(C)s1 +CCOC(=O)c1ccc(OCCN2CCOCC2)c(N)c1 +COc1cc(NC(=O)Cc2c(F)cccc2F)cc(OC)c1 +O=C(Cn1c(=O)oc2ccccc21)Nc1ccccc1OC(F)F +Cc1cc(Br)ccc1NC(=O)c1cc(N)ccc1F +COCCN(Cc1ccccc1)C(=O)c1cnc2sccn2c1=O +O=C(NCc1ccc2c(c1)OCO2)NCC(F)F +O=C(NCc1ccc(F)cc1F)c1ccccc1F +CCCCNC(=O)Cn1nc(C#N)cc1-c1ccccc1 +COc1ccc(-c2ccc(=O)[nH]n2)cc1S(=O)(=O)N1CCCCC1 +COCCn1c(SCCC#N)nc2ccccc2c1=O +COC(C)C(=O)OCc1coc(-c2ccc(C)cc2)n1 +CCOC(=O)CC(C)CNC(=O)c1cc(C)c(C)s1 +Cc1ccc2c(COC(=O)C3CCCO3)cc(=O)oc2c1C +COCC(O)CNC(=O)c1ccc2nc(-n3cccc3)sc2c1 +CCSc1ccc2nc(NCCN3CCOCC3)sc2c1 +Cc1ccc(-n2ncc3c(NCC(C)O)ncnc32)cc1 +COC(=O)Nc1ccc(CNC(=O)N(C)Cc2ccccn2)cc1 +Cc1occc1C(=O)c1ccc(NS(C)(=O)=O)cc1 +Cc1[nH]ncc1CCCNC(=O)c1ccc2c(c1)nc(C)n2C +CN(CCOCC1CC1)C(=O)C1Cc2ccccc2C(=O)O1 +CCOC(=O)C(C)Oc1ccc(C)cc1C(C)O +Cc1cc(C(=O)N(CCc2cccc(F)c2)C2CC2)[nH]n1 +COc1cc(OC)c(-c2cc(CO)c(C)o2)cc1OC +CC(C)N(C)c1cccc(NC(=O)Cn2ccccc2=O)c1 +CN(c1ccc(C(=O)Nc2ccc(F)cc2F)cc1)S(C)(=O)=O +CC(C)Oc1cccc(NC(=O)NCCCc2ccccn2)c1 +NC(=O)N1CCCC(C(=O)NC(c2ccc(F)cc2)C2CCCO2)C1 +COc1ccc(CNC(=O)c2cccc(-n3cnnn3)c2)cc1 +Cc1cccc(OCC(=O)OC(C(N)=O)c2ccccc2)c1 +Cc1nnc(SC2CC(C)OC2=O)n1-c1ccccc1 +CCCN1C(=O)CCC2CN(C(=O)c3cc(O)n[nH]3)CCC21 +CC(NC(=O)Nc1ccccc1)C(=O)NC(C)C(=O)NC(C)(C)C +CCOC(=O)c1sc(NC(=O)c2ccn(CC)n2)nc1C +CC1CCc2nc(NC(=O)COc3ccc(C(N)=O)cc3)sc2C1 +COC(=O)c1cc(Br)cc(Cl)c1N +CCCNC(=O)C1CCCN(C(=O)Nc2cccs2)C1 +O=C(Cc1cc(F)c(F)cc1F)Nc1ccc2[nH]ccc2c1 +CCn1cc(Cl)c(C(=O)N2CCn3c(nnc3C(C)C)C2)n1 +CNC(=O)C1CCC(NC(=O)Nc2ccncc2)CC1 +N#CC(C(=O)c1ccn(-c2ccccc2)n1)c1nnc2n1CCCCC2 +Cc1nc(COC(=O)c2ccc(OCC(F)F)nc2)sc1C +Cn1c(C(=O)NCc2ccccc2)nc2cc(O)ccc21 +Cc1[nH]ncc1CCCNC(=O)c1ccc(-n2ccnn2)cc1 +COc1ccc(S(=O)(=O)CC(=O)Nc2cccc(C)c2)cc1 +CC(Cc1ccc(F)cc1)NC(=O)CN(C)c1ccc(C#N)cn1 +Cc1nc2c(N(C)CCC(O)c3ccccc3)ncnc2o1 +COCCn1cc(NC(=O)NC2(c3ccccc3F)CC2)cn1 +Nc1csc2nc(-c3ccc4c(c3)CC(=O)N4)nn12 +CN(C(=O)c1cn2cc(N)ccc2n1)c1ccccc1 +Cc1nc2ccccc2n1CCNC(=O)CCCC(=O)N(C)C +CN(C)C(C(=O)NCCc1ccc(O)cc1)c1ccccc1F +Cc1nn(CC(C)C)c(C)c1CCC(=O)Nc1ccn(C)n1 +CCCC(=O)N(Cc1ccco1)c1nc2c(OC)cccc2s1 +CCOC(=O)c1ccccc1NC(=O)c1c(Cl)cnn1CC +COc1ccc2nc(-c3nc(-c4ccc(C#N)cn4)no3)ccc2c1 +N#Cc1ccc2[nH]c(C3CCN(C(=O)C4CCCCC4)C3)nc2c1 +CCc1nnc(SCC(=O)Nc2ccccc2)nc1CC +CCOC(=O)COc1nc(-c2ccccc2)c2c(c1C#N)CCC2 +C=CCNS(=O)(=O)c1ccc(Br)c(C(=O)OC)c1 +O=C(NCc1n[nH]c(=O)[nH]1)C1COc2ccc(F)cc2C1 +CC(C)C(=O)Nc1ccc(OC2CCN(C3CC3)C2=O)cc1 +CSc1ncccc1C(=O)OCC(=O)Nc1ccc2c(c1)CCC2 +CC(=O)c1cccc(OCC(=O)Nc2cccc(F)c2)c1 +O=C1COc2cc(NC(=O)c3ccco3)ccc2N1 +CCC(NC(=O)c1cnc(C2CCCO2)s1)c1ccncc1 +COCc1ccccc1CNC(=O)c1c(C)nn2c(C)cc(C)nc12 +CNS(=O)(=O)c1c[nH]c(C(=O)N2CCC(C(N)=O)CC2)c1 +CCNC(=O)CSc1ccc(Br)cc1C +Nc1cccc2[nH]nc(-c3ccc4c(c3)OCO4)c12 +CCn1nc(C)c(CNC(=O)NC2CCCC(C(F)(F)F)C2)c1C +CC(OC(=O)C1CCOCC1)c1ccc2c(c1)OCCO2 +Cc1cc(NC(=O)NCc2ccccc2F)n(Cc2ccccc2)n1 +CC(=O)c1ccc(C#CCNC(=O)c2ccco2)cc1 +CCOc1ccc(C(=O)N2CCN(c3ccccc3OC)CC2)cn1 +CC1(C(=O)Nc2nnc3ccccn23)CC1(Cl)Cl +COc1cccc(-c2cn(-c3ccc(Cl)c(N)c3)nn2)c1 +C=C(C)Cn1c(N(C)C)nc2c1c(=O)[nH]c(=O)n2C +Cc1noc(-c2csc(C(=O)NCc3ccccc3F)n2)n1 +CCOCC(C)n1c(C2CC2)nc2cc(N)ccc21 +CC(C)c1csc(CNC(=O)c2cccc(F)c2N)n1 +O=C(c1ccc(-n2cccc2)cc1)N1CCCC(CO)C1 +O=C(C1CCCO1)N1CCC(c2c[nH]c3ccccc23)CC1 +Cc1cc(F)ccc1C(O)CSc1nc(-c2ccncc2)n[nH]1 +CCN1CC(C(=O)Nc2cc(Cl)ccc2Cl)CC1=O +Cc1cc(OC(C)C(=O)NCC2CCCO2)ccc1Cl +COc1ccc(CNC(=O)NCC(C)CO)c(OC)c1 +CN(C)C(=O)c1ccc(OC(=O)c2cnc(C3CCCO3)s2)cc1 +CC(C)CCNC(=O)c1ccc(-n2cnc3cccnc32)cc1 +COc1ccc(C(=O)Nc2c(C)cccc2C)c(N)c1 +Cc1ccc(CS(=O)(=O)NCc2ccc3c(c2)OCO3)cc1 +Cc1ccc(NC(=O)c2nc3cc(N)ccc3n2C)cc1C +CC(C(=O)NCC1CCCCC1)N1CCn2c(nn(C)c2=O)C1 +CCCn1c(C)c(C)c(C(=O)OC(C)(C)C)c1N +CCS(=O)(=O)NCCCN1CCSc2ccccc21 +COCc1ccc(CNc2ncnc3[nH]ncc23)cc1 +CCOC(=O)N1CCC(Nc2nccc(-c3ccncc3)n2)CC1 +Cc1cnn(C2CN(CC3=NS(=O)(=O)c4ccccc4N3)C2)c1 +COc1c(Cl)cccc1NC(=O)c1cccs1 +C#CCOC(=O)CCc1nc(-c2ccsc2)no1 +Cn1cc(C(=O)NCc2cccc(C(N)=O)c2)c(C(C)(C)C)n1 +OCc1nnn(-c2cccc(F)c2)c1-c1ccccc1Cl +CC(C)NC(=O)c1ccccc1NC(=O)c1cc(F)c(F)c(F)c1 +COc1ccc(Oc2cc3c(cc2N)n(C)c(=O)c(=O)n3C)cc1 +CN(CCc1ccccn1)S(=O)(=O)c1cccc2cnccc12 +CCCNC(=O)Cn1c(-c2ccccc2)nc2c(N)cccc21 +CCc1ccccc1NC(=O)C1CCCN1C(=O)c1cccc(F)c1 +COC(=O)Nc1cccc(OCC(=O)Nc2c(C)cccc2C)c1 +CCSc1nnc(NC(=O)c2ccccc2-n2cccn2)s1 +Cc1cc(CN2CCN(C(=O)c3cc4c(s3)CCC4)CC2)on1 +CCC(CC)N(C)C(=O)NC1CCC2(CC1)OCCO2 +CCC(NS(=O)(=O)c1cn[nH]c1)c1cccc(Cl)c1 +CC1CC(C)CN(C(=O)CNC(=O)Cc2cccc3ccccc23)C1 +COc1ccc(Cl)cc1CN1CCN(C(=O)c2ccc[nH]2)CC1 +NC(=O)COc1cccc(C(=O)Nc2ccc(-c3ccccc3)cc2)c1 +Cc1cc(-c2nnc3sc(Cc4ccccc4)nn23)[nH]n1 +O=C1CC2CCC(C1)N2c1cc(Cl)ccc1F +CC(OC(=O)CC1C=CCC1)C(=O)Nc1ccc(C(N)=O)cc1 +CC(C)c1nc(CCNC(=O)Nc2cccn3cnnc23)cs1 +OC(Cc1nc2ccccc2n1C(F)F)c1cccs1 +Cn1c(=O)c2c(ncn2CC(=O)NCC2(O)CCCC2)n(C)c1=O +N#Cc1ccc(F)c(COc2ccc(N)cc2F)c1 +Cn1ccc(-c2nnc(NC(=O)c3c(F)cccc3Cl)o2)n1 +O=C(CC1COC2CN(c3ncc(F)cn3)CC12)NCc1ccco1 +CNc1cc(-c2c(OC)cc(C)c(Cl)c2C)nc(C)n1 +CC1(C)CN(C(=O)CCn2ncc(=O)c3ccccc32)CCO1 +N#Cc1ccc(NC(=O)Cn2ncc3ccccc3c2=O)cc1Cl +CC1CCCC(CNC(=O)Cn2nnc3ccccc3c2=O)C1 +COCC1CCN(C(=O)c2cn(CCC3CCCCC3)nn2)C1 +O=C(Nc1ccccc1F)c1csc(-c2cnccn2)n1 +Cc1ccc(SCCn2cnc3ccsc3c2=O)cc1 +CSc1nsc(NC(=O)CCc2nc3ccccc3s2)n1 +Cc1nc2ncnn2c(O)c1NC(=O)Nc1ccccc1Cl +Cn1nccc1-c1nn2c(-c3cccs3)nnc2s1 +N#CCn1c(CN2CCc3sccc3C2)nc2ccccc2c1=O +CCN(CC(F)(F)F)C(=O)COC1CCCC1 +CCOC(=O)N1CCN(c2cc(C)c(C#N)cc2F)CC1 +CN(C(=O)c1cc(=O)[nH]c2ccccc12)c1cccc2ncccc12 +Cc1ccc(NC(=O)c2cc(C#N)c[nH]2)cc1S(C)(=O)=O +CC(C)N(C)C(=O)NC(CC(F)(F)F)c1ccc(F)cc1 +CC(=O)c1ccccc1NC(=O)COC(=O)c1ccc(Cl)c(N)c1 +N#Cc1cccc(NC(=O)C2COc3ccc(F)cc3C2)c1 +NC(CS(=O)(=O)c1ccccc1)c1cc(F)ccc1F +COc1cc(F)c(C(C)NC(=O)c2ccn(C)c(=O)c2)cc1OC +Cc1cc(F)ccc1S(=O)(=O)Nc1cccc(C(N)=O)c1C +Cc1ccc(OC(C)C(=O)N2CCN(c3ncccn3)CC2)cc1C +COCc1nc2nccc(-c3ccccc3Cl)n2n1 +Cc1sc2ncnc(N3CCC(S(N)(=O)=O)CC3)c2c1C +Nc1ccc2c(c1)C(=O)N(c1cc(F)ccc1F)C2 +CCOc1ccc(Cl)cc1S(=O)(=O)NCCO +CC(C)COc1ccc(C(=O)N(C)C(C)C(O)c2ccccc2)cc1 +C(=CCSc1ncccn1)CSc1ncccn1 +CC(CCc1ccco1)NC(=O)c1ccc2c(c1)CCC(=O)N2 +COc1ncnc2c1CN(Cc1ccc(OC)c3ccccc13)CC2 +CC(C)Cn1c(-c2cccc(C(=O)NC3CC3)c2)nc2cccnc21 +Cc1nn(C)c(C)c1OC(=O)C1CCCN(C(=O)C2CC2)C1 +Cc1ccc(C(=O)NC2CCSc3ccccc32)cc1F +COc1ccc(NC(=O)c2ccc(CNC(N)=O)cc2)c(OC)c1 +CC(=O)c1ccc(NC(=O)CSc2nnc3n(N)cnn23)cc1 +CCn1ccc(C(=O)Nc2cnn(CC3CC3)c2)n1 +O=C(NCC1CCCO1)Nc1cc(F)ccc1OCC1CCCO1 +N#CC(CC(=O)NCc1ccccn1)c1ccc(F)cc1 +O=C(NCCCN1CCCC1=O)c1ccc2[nH]nnc2c1 +O=C(c1ccc(F)c(S(=O)(=O)N2CCCC2)c1)C1CC1 +CC(=O)Nc1ccc(NC(=O)NCc2ncn(C)n2)c(Cl)c1 +Cc1cc(N)cnc1Sc1nc2ccccc2o1 +O=C(NCC#Cc1cccc(C(F)(F)F)c1)NCCc1cccnc1 +CC(NC(=O)CSc1ncn[nH]1)c1ccc(OC(F)(F)F)cc1 +CCc1c(C(=O)N(C)CCc2ccccn2)cnn1-c1ccc(C)cc1 +CN(CC(O)CO)c1cc(-c2ccccc2F)nc2ccnn12 +OC(COc1cccc2[nH]ccc12)Cn1cnnc1 +COCc1ccccc1CNC(=O)COc1ccc(F)cc1 +CCCCC1CCC(NC(=O)C(C)NC(N)=O)CC1 +CC(C)c1nn(C)cc1C(=O)Nc1ccc(OC(F)(F)F)cc1 +Cc1n[nH]c(C2CN(C(=O)c3ccc(OCC4CC4)cc3)CCO2)n1 +CN1CCOC(CNCc2ccc(OCc3ccccn3)cc2)C1 +Cn1cc(CC(=O)NCc2cccs2)c2cccnc21 +O=C(Nc1cc(F)ccc1F)c1cc(-c2cccnc2)[nH]n1 +CCOC(=O)CNC(=O)C(C)Oc1ccc(Cl)cc1C +CCN(Cc1ccccc1NC(=O)c1cc2ccc(C)cc2[nH]1)C(C)=O +COCCCNC(=O)CSc1ccccc1C +COCCNC1=NS(=O)(=O)c2cc(N(C)C)ccc2N1 +Cc1n[nH]c2c1C(c1c(Cl)cccc1Cl)C1=C(COC1=O)N2 +CCCc1cc2c(=O)n(C(C)Cn3cccn3)cnc2s1 +CCCS(=O)(=O)N1CCCCC1C(=O)NCc1cccc(C)n1 +Cc1ccc2c(CC(=O)Nc3ccc(C(N)=O)cc3)coc2c1 +CCOc1ncccc1C(=O)OCC(=O)Nc1c(C)cc(C)cc1C +CCC1CCCN(S(=O)(=O)CCCC(=O)OC)C1 +CNC(=O)CC(c1cc(C)c(OC)cc1C)C1CC1 +CCOc1ccc(COC(=O)c2c(C)nn3cccnc23)cc1OC +NC(=O)Nc1ccccc1CN1CCc2ccccc21 +Cc1nc(CNC(=O)C2Cc3cc(F)ccc3O2)oc1C +Cn1cccc1C(CNS(=O)(=O)c1ccccc1)N1CCOCC1 +CCC1CCC(N(C)C(=O)c2cccc(N)n2)CC1 +CC1CCN(C(=O)c2ccc(Cn3cccn3)cc2)CC1 +COC(=O)C(NC(=O)CSc1nc(C)cc(C)n1)c1ccccc1 +CNC(=O)Cn1ccc2ccc(NC(=O)NCc3ccccc3)cc21 +CC1Cc2ccccc2N1S(=O)(=O)CCCCC#N +O=C(Cc1c[nH]c2ccccc12)Nc1ccnn1Cc1cccs1 +CNC(=O)C(C)NC(=O)CCCc1cc(F)ccc1F +NC1=NC(=O)C(Cc2ccc(Br)cc2)(c2ccco2)N1 +CCN(CCC#N)C(=O)c1cc(OC)c(OC)cc1C +O=C(NCc1cccc(COc2ccccc2)c1)c1cnccn1 +Cc1cc(C(=O)OCC(=O)Nc2ccccc2)c(C)o1 +CC(C#N)Sc1nnc(-c2ccccc2F)n1N +CC(=O)NCCCOC(=O)c1cc(C)c(Br)cc1C +COC(=O)NCCCC(=O)Nc1ccc(C#N)c(Cl)c1 +CN(CC(F)(F)F)C(=O)C(C)(C)n1cc(Br)cn1 +C#CCN(C(=O)C(C)NC(N)=O)C1CCCCC1 +CC(N)C(=O)OCc1ccc2nc(C3CC3)[nH]c2c1 +CN(Cc1ccc(C(N)=O)cc1)Cc1nc2ccccc2s1 +Nc1nncc(-c2ccncc2)c1C(=O)NCc1ccccn1 +COc1ccc(NC(=O)NC(C)c2ccc3c(c2)CC(=O)N3)cn1 +CCc1cc(N(C)Cc2noc(C3CC3)n2)n2nc(C)c(C)c2n1 +COC(=O)CCC(=O)N(C)c1ccc(F)c(F)c1 +Cc1ccc(C(C)N(C)C(=O)Nc2ccncc2)cc1 +O=S(=O)(c1ccc2c(c1)CCCO2)N1CCNCC1 +COc1cccc(CNC(=O)Cn2c(N)nc(C)c(C)c2=O)c1 +O=C(NCc1cccc2cccnc12)c1ccoc1 +Cc1ccccc1N1CC(C(=O)N2CC(C)CC(C)C2)CC1=O +N#CCCOCc1nc2ccccc2n1CCC#N +Cc1ccc(NC(=O)NC2CCN(C(=O)c3ccco3)CC2)c(C)c1 +O=C(Nc1ccnn1CC1CC1)c1cc(F)cc2[nH]cnc12 +O=C(NCc1ccncc1)c1cc2c(ccc3ccccc32)oc1=O +CNC(=O)c1cc(S(=O)(=O)Nc2cccc(F)c2)cs1 +COc1ccc(OC)c(S(=O)(=O)N(C)C(C)(C)C#N)c1 +CCn1c(SCCOC(C)C)nc2cc(S(N)(=O)=O)ccc21 +CNC(=O)c1cc2cnn(C(C)C(C)C)c2nc1N +Cn1cc(NC(=O)NCc2ccc(S(N)(=O)=O)cc2)cn1 +CCOC(=O)N1CCN(C(=O)Nc2cccc(C#N)c2)CC1 +Cc1ccc(NC(=O)c2ccc(CSc3ncn[nH]3)cc2)nc1 +O=C(CC1C=CCC1)Nc1cnn(-c2ccccc2F)c1 +COc1ccc(C2(C(=O)NC3CCC(O)CC3)CCCC2)cc1 +Cn1nccc1CN1CCN(C(=O)c2ccc(F)cc2F)CC1 +Cc1nc2ccccc2c2nn(CC(N)=O)c(=O)n12 +O=C(CSc1ccccc1)N1CCOc2ccccc21 +CCOc1ccc2c(c1O)CCNC2c1scnc1C +O=C(NCCOCC(F)(F)F)NCc1ccco1 +CC(CO)C(C)NC(=O)Nc1ccc(C(=O)N2CCCCCC2)cc1 +CC(Sc1nncn1C)C(=O)Nc1nccs1 +Cc1cnc(C(C)NC(=O)C(C)Sc2ccccn2)s1 +COc1ccc(O)c(C(=O)N2CCC(OC)CC2)c1 +COC(=O)c1cnn2c(C(F)(F)F)cc(C(F)(F)F)nc12 +O=C(Cc1ccccc1)N1CCC2C1CCC(=O)N2c1cccnc1 +CC(C)(CNC(=O)CSc1ccncc1)c1cccs1 +COC(C)c1cccc(NC(=O)NCC(C)c2nc(C)cs2)c1 +Cc1ncsc1C(=O)Nc1cccc(Br)c1 +CCCn1c(C)cc(C(=O)COc2ccc(-n3cnnn3)cc2)c1C +COC(=O)C1(N(C)C(=O)c2cc(F)c(F)cc2F)CCCCC1 +C#CCNC(=O)N(C)C(C)c1cccc(Cl)c1 +CCCn1nc(-c2cc(OC)ccc2OC)cc(C#N)c1=O +Nn1cnnc1SCC(=O)Nc1ccc2c(c1)OCO2 +N#Cc1ccc(OCCN2CCN(C(=O)CO)CC2)cc1 +Cc1cccc(C)c1NC(=O)c1onc(S(C)(=O)=O)c1N +CNC(=O)c1cccc(NC(=O)Cc2ccc(F)c(F)c2)c1C +O=C(Cc1ccc(F)cc1)OCCc1cccnc1 +CC(CCCO)NC(=O)NCc1cc(Br)cs1 +COC(=O)CC1C(=O)NCCN1C(=O)NC1CCCCC1 +COc1cc(CCNC(=O)Cc2ccc(F)cc2F)ccc1O +O=C(Nc1nnc(-c2ccc3c(c2)OCO3)s1)c1ccco1 +COC(=O)c1ccc(NC(=O)C(C)NC(C)=O)cc1 +CCNC(=O)c1cccc(CNC(=O)NCCc2ccccc2)c1 +O=C(Nc1ccc(-c2cnco2)cc1)c1cnc(C2CCCO2)s1 +O=C(Nc1ccccc1C(=O)NCC1CCCO1)c1ccccc1F +COc1ccc(OC)c(CN(C)C(=O)c2cccc(Cl)c2)c1 +Cn1nc(-c2ccccc2N)c2c1CCN(C(=O)OC(C)(C)C)C2 +CC(NC(=O)c1cc2c(s1)-c1ccccc1OC2)c1cccnc1 +CC(=O)NC(C)(C)c1noc(CCSc2ccc(C)c(C)c2)n1 +O=C(NCC1CCC1)N1CCCN(C(=O)c2cccs2)CC1 +O=C1CN(S(=O)(=O)c2cc(C(F)(F)F)ccc2Cl)CCN1 +Cc1nnc(C2CCCN(C(=O)c3ccc4c(c3)OCO4)C2)s1 +O=C(OC1CC2C(=O)NCC(=O)N2C1)c1ccccc1 +CCN(C)c1cc2n(c(=O)n1)CCc1cc(OC)c(OC)cc1-2 +CCCNC(=O)c1ccc(C)c(S(=O)(=O)N2CCOCC2)c1 +Nc1cc(CCC(=O)NCC2CCCO2)ccc1N1CCCC1 +COC(=O)N1CCCC(C(=O)NCc2csc(=O)[nH]2)C1 +CC(=O)N1CCC(C(=O)Nc2cc(C(C)(C)C)on2)CC1 +COc1ccc(CCNc2cc(C)ncn2)cc1OC +COc1cc(C(N)c2nc3c(s2)CCC3)cc(OC)c1O +CCn1nc(C)c2nc(C(C)C)nc(NCc3ccco3)c21 +CC(C)c1cc(NC(=O)Cn2cnc3sccc3c2=O)on1 +CC(C)CN(C)S(=O)(=O)c1ccc2c(c1)CCC(=O)N2 +Cc1ccc(NCC(=O)c2cccc(N)c2)c(C)c1 +CCc1nc(CC(=O)Nc2ccc(OCC3CCCO3)cc2)cs1 +COC(=O)c1nnn(-c2nonc2N)c1CSc1ccccn1 +Cc1cc(C)n(CCCNC(=O)c2cc(-c3ccc(C)o3)n[nH]2)n1 +Cc1cc(C(=O)N2CCC3(CCC(=O)N(CC(C)O)C3)CC2)[nH]n1 +CN(Cc1ccccc1)C(=O)c1cnn(-c2ccccc2)c1N +O=C(CSc1ccc(F)cc1)Nc1ccnn1C1CCCC1 +CCOc1ccc(CN2C(=O)C3(OCCCO3)c3ccccc32)cc1 +CCc1noc(CC)c1CNC(=O)NCc1ccnc(OC)c1 +CC(C)Oc1ccc(-c2cccc(F)c2C(N)=O)cc1 +Cc1nc(Nc2ccccc2)n2c(=O)[nH]nc2c1C +CCOC1CCCN(C(=O)NCc2cn(-c3ccccc3)nn2)C1 +CCc1ncnc2c1CCN(Cc1cccnc1)CC2 +Cc1ccc(-n2cc(C(=O)NC3CCC(C)CC3)nn2)cc1 +CNC(=O)c1nc(C)n(-c2c(Cl)cccc2Cl)n1 +Cn1nc(C2CCCC2)cc1NC(=O)c1csnn1 +COc1ccc(C(C)NC(=O)C(C)OC)c(OC)c1 +CC(C)C(=O)c1ccccc1NC(=O)CCN1CCCC1=O +CC(C)C(NC(=O)c1ccco1)c1nc2ccccc2[nH]1 +COc1ccccc1C(=O)N1CCN(C(=O)c2ccccc2F)CC1 +NC(=O)c1ccccc1NC(=O)C1CC1(Cl)Cl +O=C(NCc1ccncc1)Nc1ccc(F)c(F)c1F +CCCN(CCC)C(=O)NCc1ccc(C(=O)NC)cc1 +CCCn1nnc(-c2nc(-c3ccc(Cl)cc3)no2)c1N +O=C(c1ccc(Cn2cnnn2)cc1)N1CCC(c2ccncc2)CC1 +COc1ccc(OCCCC(=O)N(C)c2ccc(O)cc2)cc1 +COc1ccc(-n2nnc(C(=O)Nc3cccc(F)c3)c2C)cc1 +CCOCCNC(=O)CNC(=O)c1cccc(F)c1 +COC(=O)N(C)c1ccc(NC(=O)c2cn3cccnc3n2)cc1 +Cc1ccc(Br)c2c1CCNC2c1nc[nH]n1 +Cc1ccccc1C(=O)N1CCN(c2ccc3c(c2)CCC3)C(=O)C1C +COc1ccc(CCNC(=O)NCc2ccco2)cc1OC +CN(Cc1ccc2c(c1)OCCO2)C(=O)c1ccncc1 +CCNC(=O)C(C)NC(=O)NCCCNC(C)=O +Cc1cc(NC(=O)c2cc(CC(C)C)n[nH]2)ccc1C(=O)N(C)C +CCS(=O)(=O)N(C)C(=O)CCc1c[nH]c2ccccc12 +Cc1cc(C(C)Nc2ncnc3[nH]cnc23)c(C)o1 +c1ccc(-c2nnn(Cc3coc(-c4cccs4)n3)n2)cc1 +CC(=O)NS(=O)(=O)c1ccc(NC(=O)c2ccccc2C)cc1 +Cc1[nH]c2ccccc2c1C(=O)N=c1[nH]c2ccccc2[nH]1 +COc1ccccc1NC(=O)c1c(C)noc1-c1ccccc1 +Cc1cc(N2CCOCC2)nc(SCc2cn3cccnc3n2)n1 +Cc1noc(CN2C(=O)c3cccc4cccc2c34)n1 +N#Cc1cccc(-c2ncnn2CC2(O)CCCCC2)c1 +CC(Sc1ccccc1)C(=O)N1C(C)COCC1C +CC(C)(C)c1nnc(NC(=O)NCc2ccc3c(c2)OCO3)s1 +O=C(CCCc1nc2ccccc2s1)NCc1nncn1C1CC1 +Cn1nc(NC(=O)COc2ccccc2)c2cccnc21 +O=C(NCC1CC1)c1ccc(Br)cc1O +CCn1c(=O)c2sccc2n(CC(=O)N2CCOCC2)c1=O +Cc1cc(NC(=O)CSc2ncccc2Cl)on1 +O=C(c1cc(Br)ccc1F)N1CCN(CCO)CC1 +Cn1ncc2c(SCn3nnc4ccccc4c3=O)ncnc21 +COC(=O)C(CO)NC(=O)OCc1ccccc1 +CN(CC(=O)Nc1ccccc1O)C(=O)OC(C)(C)C +CC(C)Cc1nc2c(OCCO)cccc2s1 +CCN(CC1CCCO1)C(=O)c1cc(C2CC2)nc2onc(C)c12 +COc1ccc(NC(C)=O)cc1NC(=O)COC(=O)c1cccn1C +CC(C)n1ncc2cc(C(=O)NC3CCCCC3)c(N)nc21 +CSc1nc2nc(OC(C)=O)cc(OC(C)=O)c2s1 +CS(=O)(=O)c1ccc(-c2ccc(NC(=O)C3CCCC3)cc2)nn1 +Cc1nn(C)c2nc(-c3cccs3)cc(C(=O)Nc3cccnc3)c12 +Cc1ncsc1C(=O)NC1CCN(c2ncccc2C#N)CC1 +CC(=O)c1ccc(S(=O)(=O)N(C)Cc2ccccc2C#N)cc1 +CCOc1ccc(OC(=O)CCc2c(C)noc2C)cc1 +COc1ccccc1CNc1ccc(F)c(C#N)c1 +CCS(=O)(=O)N1CCC(OCc2ccccc2C)CC1 +Cc1ccc(S(=O)(=O)NCCCn2cncn2)cc1C +CCOC1CC(N(C)C(=O)c2cnc3ccc(C)cn23)C12CCCC2 +COc1nn(C)cc1C(=O)N1CCN(c2cccc(Cl)c2)CC1 +Nc1ccc2c(c1)C(=O)N(Cc1cnoc1)S2(=O)=O +CCOCCOCC(=O)N(C)c1ccc(F)cc1 +CCOC(=O)C1CN(C(=O)CC(C)C)CCN1C(=O)CC(C)C +Oc1ccc(CNc2ccccc2Br)cc1 +Cc1ccc(NC(=O)CN2c3ccccc3CC2C)cc1N +CC(C)n1ncc2cc(NC(=O)COc3ccc(C#N)cc3)cnc21 +Cc1cc(NC(=O)Cc2cc(Cl)ccc2Cl)n(C)n1 +O=C(Nc1cc[nH]n1)c1c(F)cccc1Br +Cc1cccc(C(=O)N2CCC(Oc3cnc4ccccc4n3)CC2)c1 +O=C(NC1(c2ccccc2)CCC1)c1cnc2ccccn2c1=O +Cc1cnn(CC2CN(CC(=O)Nc3c(C)n[nH]c3C)CCO2)c1 +CNC(=O)C1CC2CCN(Cc3scnc3C)CC2O1 +Cc1c(Cc2ccccc2)c(=O)oc2cc(O)cc(O)c12 +CC(C)S(=O)(=O)NCc1csc(C2CC2)n1 +CCOC(=O)C1(O)COc2c1n1ccsc1nc2=O +CC(C#N)CS(=O)(=O)c1ccc(Br)cc1 +NS(=O)(=O)N1CCCN(C(=O)c2ccccc2Cl)CC1 +CCOC(=O)c1cnn2ccc(NC(=O)c3cn(C)nn3)cc12 +Cc1nn(C2CC(C)CCC2C#N)c(C)c1Cl +Cc1ccc(CC(=O)NCc2ccnc(-n3ccnc3C)c2)cn1 +CCC(C)n1ncc(C(=O)OC(C)C2CCOC2)c1C1CC1 +CC(C)NC(=O)NC(C)C(=O)NCc1ccco1 +c1ccc2c(c1)NCCN2CCOc1ccc2c(c1)OCO2 +Cc1cccc(NC(=O)CSc2nnnn2C2CCCCC2)n1 +CC(=O)Nc1cc(NC(=O)C2(c3ccc(Cl)cc3)CC2)ccc1F +Cc1cc(CNC(=O)c2cc3c(s2)CCCC3)no1 +Cc1cccc(NC(=O)Cn2cnc3c(cnn3CCO)c2=O)c1C +CC1CC1C(=O)NCc1csc(N(C)C(=O)C2CC2C)n1 +CC(NCc1ccco1)C(O)c1ccc(F)c(F)c1 +Cc1cc(S(=O)(=O)N(CCC(N)=O)c2ccccc2)c(C)s1 +Cc1ccc(-c2csc(N3CCOCC3)n2)s1 +Cc1cc(C(C)(O)CNC(=O)c2cc3ccccc3[nH]2)c(C)o1 +CC(=O)c1sc(NC(=O)c2ccc(OC(C)C)cc2)nc1C +COc1ccc(-c2oc3ccccc3c(=O)c2OCC(N)=O)cc1 +CN(C)C(CNCc1ccc(S(C)=O)cc1)c1ccco1 +CC(C)(CNC(=O)C1CCCN1C(=O)c1ccco1)N1CCOCC1 +O=C(NCCc1nc(Cc2ccccc2)no1)c1ccnnc1 +O=C(NCCCC1CCCCC1)Nc1ccncc1 +CN(CC1CCC1)C(=O)NCc1ccnc(OC2CCC2)c1 +CCCc1nc(CSc2ccncc2N)no1 +CC(=O)Nc1ccc(OCC(O)COc2c(C)cccc2C)cc1 +Cc1nc(CC(=O)N(Cc2cnn(C)c2)C2CCCCC2)cs1 +COCC(=O)NCc1cc(-c2ccccn2)n(C)n1 +CCCCc1oc2ccccc2c1CN(C)C(=O)C(C)NC(C)=O +CC(NC(=O)Nc1ccccc1)C(=O)NCc1cccs1 +C=CCNC(=O)c1ccc(NC(=O)c2ccc(COC)cc2)cc1 +O=C(CNC(=O)c1cccs1)Nc1nccs1 +N#Cc1ccc(CN2CCN(c3ncccc3Cl)CC2=O)cc1 +CCN(CC)C(=O)CSc1nnc(-c2ccccc2F)n1N +N#CCCN(Cc1ccco1)Cc1cc(=O)oc2cc3c(cc12)CCC3 +C=CCNC(=O)c1ccc(NC(=O)c2cnc3c(c2)c(C)nn3C)cc1 +CSc1ncccc1C(=O)Nc1cc(C)cc(C)c1 +CCN(CC)C(=O)C1=C(C)N=C(C)C(C(=O)N(CC)CC)C1 +CC(C)c1nn(-c2ccccc2)c2c1C(c1ccoc1)CC(=O)N2 +Cc1ccc(CNC(=O)OC(C)(C)C)c(OCC2CCOC2)c1 +CC(NCC(C)(O)c1ccccc1)c1cccnc1 +Cc1ccc(S(=O)(=O)N2CCN(Cc3nnc(C)o3)CC2)cc1 +CN(Cc1nnc2n1CCC2)C(=O)Cc1cccs1 +CCN(CC)C(=O)C1CC(=O)Nc2cc(F)ccc21 +CCN1CC(C(=O)N(C)c2cccc3ncccc23)CC1=O +O=S(=O)(NC(C1CC1)C1CC1)c1ccccc1Cl +Cc1ccc(-c2cc(C(=O)N3CCCC(C(N)=O)C3)[nH]n2)cc1 +Cc1ccc(OCc2ccc(C#N)cc2F)c(S(=O)(=O)N(C)C)c1 +CC(NC(=O)NC1CCC(O)CC1)c1cccc(Cl)c1 +C#CCOc1ccc(NC(=O)N(C)CC(O)C(F)(F)F)cc1 +O=C(NCc1ccc(F)cc1)c1ccc(F)cc1F +NC(=O)C(NCC(F)(F)F)c1ccc2c(c1)CCO2 +CCCCCNC(=O)c1cccc(-n2cccn2)n1 +COc1cc(NC(=O)c2cnc3ccccc3n2)cc(OC)c1 +O=C(NCc1cccnc1)C1COc2ccccc2O1 +Clc1ccc(Nc2ncnc3n[nH]cc23)cc1Cl +CC(CC(=O)NC(C(N)=O)C(C)(C)C)c1ccccc1 +CCN(Cc1ccco1)C(=O)c1cc2cc(C)ccc2[nH]1 +COc1cccc(C(=O)N2CCCCC2c2cccn2C)c1F +Cc1cc(N2CCOC(c3nc(C)cs3)C2)nc(N)n1 +CCC(C(N)=O)n1cc(CO)c2cc(F)ccc21 +N#Cc1ncc(Br)c2c(N)cc(Br)cc12 +CCOC1CCCN(C(=O)c2ccc(N)nn2)C1 +COC(=O)c1sc(NC(=O)c2cnn(C)c2C)nc1C1CC1 +COc1ccc(-n2cc(Cn3c(=O)[nH]c4ccccc4c3=O)nn2)cc1 +Cc1c(C(C)NC(=O)CCNS(C)(=O)=O)oc2ccc(F)cc12 +O=S(=O)(NCC#Cc1cccc(Cl)c1)c1ccccc1 +c1ccc(Cn2nnnc2Nc2ccccc2)cc1 +Cc1cc(-c2nnc(CN(Cc3ccco3)C3CCCC3)o2)c(C)o1 +CNC(=O)c1cc(NCc2cnc(C)s2)ccc1Cl +COc1ccc(F)cc1NC(=O)NCc1cn(C)nc1C(F)(F)F +CC=Cc1ccc(OCC(=O)OC(C)C#N)c(OC)c1 +COc1ccccc1-c1noc(-c2cc(C)oc2C)n1 +COC(=O)C1(N(C)C(=O)c2cccc(F)c2)CCCCC1 +CCC(C)NC(=O)C(C)NC(=O)NCCc1ccco1 +CN(CCC#N)S(=O)(=O)NCC(C)(C)c1ccncc1 +COc1ccc(C(=O)CNC(=O)c2cncc(F)c2)cc1 +COc1ccc(S(=O)(=O)N2CC(NC(=O)C3CC=CC3)C2)cc1 +CC(C)=CCOc1cc(C)nc2cc(C3CCOCC3)nn12 +Cc1ccc(N2CCCC2=O)c(C(=O)N2CCN(CCO)CC2)c1 +NC(c1nnc(C2CC2)o1)c1cc(F)c(F)cc1F +CCC(NC(=O)Nc1ccc2c(c1)COC2)c1ccc(F)cc1F +Cc1ccc(NC(=O)C2CCN(C(=O)c3ccco3)CC2)cc1F +Cc1ccc(C)c(NC(=O)c2cc3c(=O)n4ccccc4nc3n2C)c1 +COc1ccc(CC(=O)NCCCn2c(C)nc3ccccc32)cc1 +COc1ccccc1OCCC(=O)N(C)C1CCCC(C)C1 +Cc1cc(C)n2nc(C(=O)OC3CCCC(C)C3)nc2n1 +O=C1CC(c2ncc[nH]2)c2c(O)nn(C3CCCCC3)c2N1 +COc1ccc(NC(=O)C(C#N)Cc2cccc(O)c2)cc1 +Cc1cc(C(=O)NCC(C2CCOC2)N2CCOCC2)sc1C +COC(C)C(=O)Nc1cccc(NC(=O)N2CCC(C)CC2)c1 +COc1c(O)c(Cl)cc2c1C(C(C)(C)CO)NCC2 +COC(=O)c1nccc2c(N)c(OC)c(OC)cc12 +COCCNC(=O)c1cc2n(n1)CCCN(Cc1ccccc1)C2=O +O=C(Nc1ccccc1N1CCCC1=O)c1ccc2[nH]cnc2c1 +CCCc1nc(CSc2nc(C)cc(N)n2)cs1 +CC(=O)c1ccc(NC(=O)N(C)Cc2ccsc2)cc1C +O=C(CC1C=CCC1)N1CCN(C2CCCC2)CC1 +Cc1cc(NC(=O)CNC(C)c2ccccc2Cl)n(C)n1 +O=C(Cc1ccccc1Cl)NC1CCCc2ccccc21 +CC(C)OCC(=O)Nc1ccccc1C(=O)Nc1ccc(Cl)cn1 +CCc1nc2n(n1)CCCC2NC(=O)c1ccoc1 +Cc1nn(CC(C)C)c(C)c1CC(=O)OCC1CCC(=O)N1 +CCC(C(=O)NCC(=O)OC)n1nnc(-c2ccc(Cl)cc2)n1 +CCc1ccc(CCC(=O)Nc2nc(C)cs2)o1 +C#CCN1CCN(S(=O)(=O)c2ccccc2F)CC1 +Cc1cccc(NC(=O)C2CCN(C(=O)OC(C)(C)C)C2)n1 +COC(=O)c1ccc(NC(=O)N2CCOC(C)(C)C2)cc1 +Cc1cccc(CN(C(=O)CN(C)C(=O)c2cccs2)C2CC2)c1 +Cc1nn(C)c(N2CCOCC2)c1CNc1nc2ccccc2s1 +Cc1ccc(OCC(=O)Nc2cccc(C(=O)N(C)C)c2)cn1 +O=C(Cc1ccc[nH]1)NC1C2CC3CC(C2)CC1C3 +CCn1cc(C(=O)N(C)C2CCCCC2)c(=O)c2c(N)cccc21 +O=C(NCCOc1ccc(F)cc1F)NCC1CCCO1 +Cc1ccc(NC(=O)NCc2cccnc2)cc1C +CSc1ccccc1C(=O)N1CC(c2nc(C)no2)C1 +c1cc(Cn2ccnc2-c2c[nH]cn2)c2cc[nH]c2c1 +CCCn1c(CN2CCC(NS(C)(=O)=O)C2)nc2ccccc21 +CC(C)c1nnc(NC(=O)c2cc(-c3cccs3)nn2C)s1 +Oc1ccc2c3c(ccc2c1)CCNC3Cn1cnnn1 +O=C(NCCc1cc2ccccc2o1)c1ccc(N2CCNC2=O)cc1 +CC(C)(C)OC(=O)N1CC(O)CC1C(=O)OCC(=O)c1ccccc1 +CCN(C(=O)c1nn(C)c2ccc(F)cc2c1=O)c1ccccc1 +Cc1cc(NC(=O)c2cc3occc3n2Cc2ccccc2F)no1 +Cc1cc(N)nc(C2(c3ccccc3)CCCC2)n1 +Cn1c(CCNC(=O)c2cccc(-n3cccn3)c2)n[nH]c1=O +Cc1ccc(CN(C)C(=O)CSc2nnc(C)n2N)o1 +CCOC(=O)N1CCC(C(=O)Nc2ccc(OC)cc2OC)CC1 +CCCc1n[nH]c(C2CN(CCn3cccn3)CCO2)n1 +Cc1ccc2[nH]nc(-c3cc(NCCO)nc4[nH]ccc34)c2c1 +Cc1ccc(O)c(C(=O)Nc2ccc3c(c2)OCC(=O)N3)c1 +CC1CCN(C(=O)c2c(Cl)cccc2Cl)CC1 +CC(=O)N1CCC(C(=O)N(C)CCOc2cccc(C)c2)CC1 +CC(Cc1c(F)cccc1F)NC(=O)CN1CC(C)OC(C)C1 +COc1ccc(CN(C(=O)NCc2ccco2)C2CC2)cc1 +Cc1nnc(NC(=O)C2CC(=O)c3ccccc32)s1 +O=C(CNc1ccc(C(=O)N2CCCC2)cc1)Nc1ccc(F)cc1 +COc1cccc(C(=O)NCC(O)c2ccc(SC)cc2)c1OC +CCNC(=O)COc1ccccc1N1CCCC(C)C1 +Cc1ccccc1C(C)NC(=O)CNC(=O)Nc1ccccc1 +Cc1ccc(C(O)CNC(=O)c2cccc(Cl)c2)c(C)c1 +Nc1ccc(=O)n(CCS(=O)(=O)c2cccs2)c1 +Cc1ccccc1-c1noc(CN2CCN(CCO)CC2)n1 +Cc1cc(NC(=O)c2cc(C)nc3cc(F)ccc23)nc(C(C)C)n1 +CCCN(CC(=O)Nc1ccccc1C)C(=O)C(C)NC(C)=O +CCCCNC(=O)C1CCC(C)N(C(=O)Nc2ccc(OC)cc2)C1 +CCn1cc(NC(=O)NCCN2CCOCC2)c2ccccc21 +COC1CCCC(OC(=O)c2ccccc2Cn2cncn2)C1 +CC(C)(C)c1cc(C(=O)OCCCn2nc3ccccn3c2=O)[nH]n1 +Cc1ncncc1C1NCCC1NC(=O)OC(C)(C)C +COC(=O)Nc1ccc(C(=O)c2ccccc2)cc1 +CNC(=O)C(NC(=O)COc1cccc(C)c1)c1ccc(F)c(F)c1 +CC(C)n1cc(Br)cc1C(=O)N1CCc2cnccc21 +O=C(NCC(=O)N1CCc2ccc(Cl)cc2C1)NCc1ccco1 +Cc1cc(C)n2nc(CC(=O)N3CC(C)OC(C)C3)nc2n1 +COC(=O)CCCCNC(=O)N1CC(C)CC(C)C1 +CCc1nn2c(C#N)c(-c3ccncc3)nc2s1 +Cc1nc(C(=O)N2CCN(c3cccc(Cl)c3)CC2)co1 +Cc1cc(C)cc(NC(=O)NCCS(=O)(=O)NCC2CCC2)c1 +Cc1ccccc1Nc1nc(C(=O)N2CCC(C(N)=O)CC2)cs1 +Cc1ccc(NC(=O)c2ccc(S(N)(=O)=O)cc2)c(O)c1 +COc1ccc(-c2csc3c(=O)[nH]c(C)nc23)cc1F +CC(=O)Nc1cc(NC(=O)c2ccccc2C)ccc1F +Cc1cc(C(=O)Cn2cccc(C)c2=O)c(C)s1 +CC1CN(C(=O)c2cnn(-c3ccc(F)cc3)n2)c2ccccc21 +CCN(C(=O)CC1C(=O)NCCN1Cc1cccc(F)c1)C(C)C +Cc1cc(N2CCOC(Cn3nc(C)cc3C)C2)n2ncnc2n1 +CS(=O)(=O)c1ccccc1C(=O)N(Cc1ccccc1)C1CC1 +CCOC(=O)c1c(Cl)c2cc(Cl)ccc2[nH]c1=O +Cc1occc1C(=O)NC(C)C(=O)NC1CCCC1 +CC(C)N(CCC(=O)NC(C)(C)C)c1ccc(N)cn1 +CCN(C(=O)c1ccc(OC)c(-n2cnnn2)c1)c1ccc(F)cc1 +CC(C)OCCN1CCN(C(=O)Cc2nnn(C(C)C)n2)CC1 +CC1CN(C(=O)c2ccc(O)c(Cl)c2)CC(C)O1 +CN(C)S(=O)(=O)n1c(C#N)nc2ccccc21 +Cc1noc(COCC(=O)N2CCC(Cc3ccccc3)CC2)n1 +O=C(NCc1ccccn1)c1ccc(N2CCCC2)nn1 +COC(=O)C(NC(=O)c1cnc2sccn2c1=O)C(C)C +COC(=O)N1CCc2ccc(NC(=O)c3cc(C)on3)cc2C1 +Cc1ccc(NC(=O)CC(C)n2nc(C)cc2C)c(C)c1 +Cc1ccc(NC(=O)CC2C=CCC2)c2[nH]ncc12 +CNC(=O)C(Cc1ccccc1)NC(=O)c1ccco1 +CCCOc1cc(C)ccc1NC(=O)NC(C)C(=O)NCC +CCOc1cc(NC(=O)c2cn(C)nc2C(C)(C)C)ccc1OC +O=C(CCn1c(=O)[nH]c2ccsc2c1=O)NCc1ccncc1 +O=C(NCCN1CCOCC1)c1cc(-c2cccc(Cl)c2)[nH]n1 +Cc1nc(CNC(C)c2nc(C3CCCCC3)no2)no1 +CC(=O)N1CCN(C(=O)Cn2ccccc2=O)CC(O)C1 +Cc1ccc(S(=O)(=O)NC2CCN(c3ncccn3)CC2)s1 +CC1CC(=O)N(C)c2ccccc2N1S(=O)(=O)c1ccc(F)cc1 +CCCCC(=O)N1CCCC1C(=O)c1ccc(F)cc1 +Cc1ccc(C2CC(C(F)(F)F)n3nccc3N2)cc1 +Cc1ncc(CNC(=O)NC(C)c2ccc(C(F)(F)F)cc2)s1 +Cn1cccc1CNc1nnc(C2CCCCC2)o1 +CC1CN(C)CCN1C(=O)c1cnn(-c2ccc(Cl)cc2)c1 +Cc1n[nH]cc1CNC(=O)c1cc2cccc(F)c2o1 +CC(C)c1ccc(-n2nnc(CO)c2C2CCC2)cc1 +CCOC(=O)Nc1nnc(Cc2ccc(Cl)cc2)s1 +COc1nc(N(C)C)nc(-n2cnc(SCc3ccccc3)n2)n1 +Cc1n[nH]c(C)c1CNc1ccc(C#N)c(C(F)(F)F)c1 +C=CCNC(NC(=O)c1ccco1)C(Cl)(Cl)Cl +O=C(NCc1cccc(Cn2ccnc2)c1)Nc1cccc2[nH]ccc12 +CCC(CC)NC(=O)CS(=O)(=O)c1ccc(C(F)(F)F)cn1 +Cc1cc2c(cc1-c1cc(-c3cc[nH]c3)nc(N)c1C#N)OCCO2 +COc1ccc2c(c1)C(=O)CC(c1ccc3c(c1)OCCO3)O2 +Cc1cc(CCNS(=O)(=O)c2ccc(F)cc2F)on1 +Cn1c(=O)c(C(=O)Nc2ccccc2F)nn(-c2ccccc2)c1=O +Cc1ccccc1C1CCCN1C(=O)c1cn[nH]c1 +CC(O)Cn1c(C2CC(=O)N(C(C)(C)C)C2)nc2ccccc21 +CC(C)(C)C(C#N)NC(=O)CNC(=O)c1ccc(C(F)(F)F)cc1 +Cc1ccc(CN2C(=O)C(N)c3ccccc32)cc1 +CCSc1cc(C(=O)Nc2c[nH]ccc2=O)ccn1 +COCCNC(=O)CNC(C)c1ccc(Br)cc1 +Cc1[nH]c(SCC(=O)N(C)C2CC2)nc1Cc1ccccc1 +COc1ccc2[nH]cc(CC(=O)OCC3CCC(=O)N3)c2c1 +CC(NC(=O)c1ccc(S(=O)(=O)NC2CC2)cc1)c1ccncc1 +CC(NC(=O)OC(C)(C)C)C(=O)NCc1cnn(-c2ccccc2)c1 +COc1ccc(OC)c(S(=O)(=O)NCc2cccnc2)c1 +CCOC(=O)c1cnc2nc(C)ccc2c1N1CCCCCC1 +CCOc1cc(CO)cc2c1OC(C)(C)C(=O)N2CC +O=C(Nc1ccc(-c2nn3cnnc3s2)cc1)c1ccccc1 +Cn1c(C2CC2)nc2cc(C3NCCNC3=O)ccc21 +CC(=O)Nc1nc(C2CCCN(C(=O)c3cnccn3)C2)cs1 +O=C(c1ccc(-n2cnnc2)cc1)N1CCCC1C(F)(F)F +C=CCN(CCO)S(=O)(=O)c1ccc2c(c1)CCCC2 +CC1CN(C(C)(C)CNC(=O)CCC2CCCC2)CC(C)O1 +CCc1nc(C)cn1S(=O)(=O)c1ccc(NC(C)=O)cc1 +C=CCNC(=O)Nc1ccc(OC)cc1C(F)(F)F +CCCc1cn(CC2CCN(c3ncnc4[nH]cnc34)CC2)nn1 +COCC(C)NC(=O)Nc1ccc(F)c(Cl)c1 +CCn1c(SCCC(=O)OC)nnc1-c1ccccc1 +CSc1nc2ncn(Cc3noc(C)n3)c(=O)c2s1 +CCS(=O)(=O)N(CCO)c1ccc2c(c1)OCO2 +CCOc1ccccc1C(=O)Nc1ccc(-n2cccn2)cc1 +CC(NC(=O)c1cccs1)C(=O)OCC1CCCCO1 +CC(=O)Nc1ccc(CCNC(=O)Nc2cnccc2C)cc1 +CC(C)N1C(=O)c2ccccc2C1C(=O)NC1CCCCCC1 +O=C(Cn1ccn(-c2ccc(F)cc2)c(=O)c1=O)c1ccc(F)cc1 +CCCNC(=O)CNC(=O)NCC1(c2ccc(F)cc2F)CC1 +Cn1ccnc1SCC(=O)NCCc1ccc(Cl)cc1 +COCCCNS(=O)(=O)c1c(C)ccc(N)c1C +Cc1nc2c(c(=O)[nH]1)CCN(Cc1cc(F)cc(F)c1)CC2 +CN(C)S(=O)(=O)N1CCCC(c2nccn2Cc2ccccn2)C1 +O=C1CCS(=O)(=O)N1CCOc1ccc(F)cc1 +CCS(=O)(=O)NCc1cccc(Cn2ccnc2C)c1 +CCSc1nnc(N)n1Cc1ccc(C(=O)OC)cc1 +CCc1onc(C)c1NC(=O)NC1CCC(C)CC1C +Cc1ccc(F)cc1NC(=O)C(C)N1CCN(c2ncccn2)CC1 +Cc1c(C(=O)Nc2nc(C3CC3)cs2)cnn1-c1ccncc1 +COC(=O)Nc1ccc(NC(=O)c2ccc(-n3ccnn3)cc2)cc1 +Cc1csc(CN2CCCN(C(=O)c3cccs3)CC2)n1 +CC(=O)Nc1ccc(SC(C)C(=O)NC2CCCC(C)C2C)cc1 +CSc1nc(C2CC2)cc(C(=O)Nc2cccc(CO)c2)c1C#N +FC(F)(F)c1cc(C2CCCN(Cc3noc(C4CC4)n3)C2)n[nH]1 +COc1ccc(-c2ccc(N)cc2)n2nc(N)nc12 +COC(=O)CN1C(=O)C(O)(C(F)(F)F)c2ccccc21 +Cc1cccc(NC(=O)N2CCC(C(=O)Nc3nccs3)CC2)c1 +COCc1ccccc1C(=O)NCCNC(=O)c1ccc(F)cc1 +N#Cc1ccc(COC(=O)CCNC(=O)c2ccsc2)cc1 +CCOc1ccc(NC(=O)NCCCn2cccn2)cc1F +CCC(C)NC(=O)c1ccc(CNC(=O)c2ccncc2Cl)cc1 +Cc1ccc2[nH]cc(CN(C)c3nccc(N4CCC(O)C4)n3)c2c1 +CC(C)(C)OC(=O)N1CCC12CCN(Cc1ccccc1)C2=O +Cc1n[nH]c(C)c1NC(=O)Nc1ccc(F)cc1OC1CCCC1 +COc1cc(C(=O)NC(C)Cc2ccccc2F)cc2c1OCCO2 +CCOC(CC)C(=O)NCc1ccc(C(=O)NC)cc1 +COC(=O)c1cn(-c2ccc(F)cc2)c(=O)c2ccccc12 +Cc1cn(-c2cc(Cl)cc(Cl)c2)c(=O)c(C#N)c1C +CNC(=O)N1CCN(c2cccc(Cl)c2)CC1 +COc1ccc(CC2COc3cc(O)cc(O)c3C2=O)cc1O +COc1ccc2c(c1)nc1n2C(CNCc2nccs2)COC1 +CCOC(=O)N1CCN(C(=O)c2ccc(NC(=O)CC#N)cc2)CC1 +COc1cc(OC)c(C2CNC(=O)N2C)cc1OC +CNC(=O)c1ccc(Cl)c(NCC(=O)Nc2ccc(C)cc2)c1 +Cn1c(C(=O)NC(C)(C)C)nc2cc(C(N)=O)ccc21 +COCC(=O)N1CCC2C1CCC(=O)N2Cc1ccncc1 +O=C(Cc1ccccc1O)NC1CCCN(c2ccccc2F)C1=O +CC(C)(C)n1ncc2c1N=C(O)CC2c1ccc2ncccc2c1 +O=C(Cc1ccon1)NCCCc1nc2c(s1)CCCC2 +CC(NCC(O)c1ccncc1)c1ccc(C#N)cc1 +Nn1c(SCc2cn3ccccc3n2)nnc1-c1ccc(F)cc1 +CN(C)c1cncc(OC2CC2)c1Br +CC(C)(C)CC(=O)NCC(=O)NCc1cccc(Cl)c1 +COCCNc1ncnc(Nc2ccc(Cl)cc2C)c1N +Cc1cc(Oc2ncccn2)ccc1NC(=O)c1ccc(=O)n(C)c1 +CC(C)C(NC(=O)c1[nH]nc2c1COCC2)C(=O)NC1CCCCC1 +Cc1nn(C)cc1CN(C)C(=O)c1nn(C)c(C)c1Br +CC(C)NC(=O)CN1CCN(C(=O)c2cc3ccccc3s2)CC1 +COCC(O)CN(C)c1ccccc1C(F)(F)F +CNS(=O)(=O)c1ccc(C)c(NC(=O)C2CCc3ccccc32)c1 +O=C(NCC(=O)N1CCN(C(=O)c2ccco2)CC1)c1ccco1 +O=C(NCc1ccc(-c2cccnc2)cc1)C1CCCO1 +Cc1cccn2c(CC(=O)NCCCn3nnc4ccccc43)cnc12 +CC(=O)Nc1cccc(NC(=O)NCCSc2ccccc2)c1C +CC1CN(Cc2c(O)c(=O)cc(CO)n2C(C)C)CC(C)O1 +Cc1ccc(NCC(O)c2ccco2)c(Br)c1 +COC(=O)CSc1ccc(S(=O)(=O)N2CCCCCC2)cn1 +COc1cc(C#N)ccc1OCc1ncc(-c2ccccc2)o1 +Cc1cccc(CN(C)C(=O)c2ccc(N)cc2)c1 +CCOC(=O)c1c(C)nsc1NC(=O)c1cccnc1 +CC(C)c1csc(CCNS(=O)(=O)c2ccc(F)cc2)n1 +CCN1C(=O)CCc2cc(NC(C)CCn3cccn3)ccc21 +CCN(CC)S(=O)(=O)NCc1ccc(C)c(OC)c1 +CC(C#N)CS(=O)(=O)c1ccc2c(c1)OCO2 +O=C(Cn1nc(C(F)(F)F)cc1C1CC1)Nc1ccon1 +CC(=O)N(CCc1ccccc1)CC(=O)NCC1(C)COC1 +CCS(=O)(=O)NCCNC(=O)c1c[nH]nc1-c1ccc(F)cc1 +Cc1ccc(NC(=O)Cn2cnc3c(C)cccc3c2=O)c(O)c1 +Cc1nn(C)c(C)c1CC(=O)Nc1cnc2c(c1)c(C)nn2C +COc1cc(Cl)c2nc(NCCN3CCOCC3)sc2c1 +CC(=O)N1CCN(C(=O)COc2ccc(CC#N)cc2)CC1 +O=C(NCC(=O)N1CCCCC1)NC1(c2ccccc2)CCCC1 +Cc1nn(C)c(C)c1C(=O)NCc1ccnc(OC2CCCCC2)c1 +CCNC(=O)c1cc(NCCS(N)(=O)=O)ccn1 +COc1cc(C(=O)Nc2nccn(C)c2=O)cc(OC)c1C +Cc1cc(C)cc(C(=O)NCc2csc(C3CC3)n2)c1 +CCOC(=O)Nc1cccc(OC(=O)C2CC(=O)N(C(C)C)C2)c1 +COCCCNc1ccc(C(F)(F)F)cc1C#N +Cc1nc(-c2ccc(C(=O)Nc3cccc(-c4cc[nH]n4)c3)cc2)no1 +COc1ccc(NC(=O)N(Cc2ccccc2)Cc2cc[nH]n2)cn1 +CC(C)c1nnc(NC(=O)CCn2cncn2)s1 +O=C1NC2(CCN(C(=O)c3ccc[nH]3)CC2)CC1c1cccnc1 +CCN(CC)c1ccc(C(=O)NCc2cn(-c3ccccc3)nn2)cc1 +CCN(CC)S(=O)(=O)NCC1COc2ccccc2O1 +CCN(C)c1ccc(C(=O)NC2CCN(C(=O)OC)CC2)cc1 +COCCNC(=O)c1ccc(N(C)C2CCC(C)CC2)nc1 +Nc1cc(Cl)ccc1C(=O)NCCc1ccc(F)cc1 +Cc1ccc(NC(=O)CCc2nc3ccccc3[nH]2)nc1 +COc1ccc(F)cc1C(=O)Nc1sccc1C(=O)NC1CC1 +CCc1cccc(CC)c1NC(=O)COc1ccccc1NC(C)=O +CCCNc1ccc(C(=O)N2CCCCCC2)nn1 +COc1cc(C(=O)Nc2c(F)cccc2F)cc(OC)c1OC +CC1CC(C)CN(S(=O)(=O)N2CCCC(n3cncn3)C2)C1 +Cc1csc(NC(=O)c2c(-n3cnnn3)sc3c2CCCC3)n1 +COc1cccc(C(=O)NCc2ccnc(OC(C)(C)C)c2)c1 +O=C(Cn1ccccc1=O)N(Cc1ccccc1)CC1CCCO1 +CNc1ccc(C(=O)NCCC2COc3ccccc3O2)cn1 +COc1ccc(OC)c(NC(=O)c2ccccc2O)c1 +CNC(=O)c1sc(Cc2cccc(Cl)c2)nc1C +CCOC(=O)CC(C)CNC(=O)N1CC(C)CCC1C +CCCCC(NC(N)=O)C(=O)Nc1nc(C)c(-c2ccccc2)s1 +CN(C)C(=O)Nc1cccc(C(=O)NCc2csc(=O)[nH]2)c1 +CC(C)NC(=O)c1ccc(NC(=O)C2CC(=O)N(C(C)C)C2)cc1 +CC(C)CCCC(C)NC(=O)CN1CCOC(C)(C)C1 +COc1cccc(CCC(=O)NCc2c(C)cc(C)[nH]c2=O)c1 +Cc1cnc(NC(=O)c2ccncc2)c(Br)c1 +CCOC(=O)C1C2C=CC3(CN(CC4CCCO4)C(=O)C13)O2 +CC(=O)N1CCN(c2csc3ccc(F)cc3c2=O)CC1 +Cc1cc(F)ccc1S(=O)(=O)NCC(O)c1ccccc1 +O=C(Nc1nc(Cc2ccccc2)cs1)C1CCCO1 +CCc1nc2n(n1)CCCC2NC(=O)NC(C)C1CCCCC1 +O=C(C1CC=CCC1)N1CCC(n2c(=O)[nH]c3ccccc32)CC1 +CN(C)C(=O)N1CCC(C(=O)NC2(c3ccc(Cl)cc3)CC2)CC1 +Cc1ccc(-c2nnn(CC(=O)c3cc(C)n(C4CC4)c3C)n2)cc1 +Cc1ccc(S(=O)(=O)Nc2ccc(OCCC(N)=O)cc2)c(C)c1 +CC(CO)NC(=O)c1ccccc1Cc1ccc(Cl)cc1 +Cc1ccc2c(CC(=O)OCCNc3cccnn3)coc2c1 +COC(C)c1nc(CC(=O)NC2CCCC2)no1 +CCNC(=O)NCCn1nc(C(F)(F)F)cc1C1CC1 +O=c1[nH]c(Cc2cnoc2)nc2scc(-c3cccs3)c12 +CC(=O)NC(C)C(=O)Nc1ccc(-c2ccccc2)cc1 +NC(=O)CC1CCN(C(=O)Cc2c(Cl)cccc2Cl)CC1 +Cc1ccc(NC(=O)C(NC(=O)c2ccco2)C(C)C)c(C)c1 +CN(C)c1ccc(C#CCNC(=O)OC(C)(C)C)cc1 +CSc1nc2nc(C)c(CC(=O)N3CCCC(O)C3)c(C)n2n1 +Cc1csc(C2(NC(=O)CCCn3cccn3)CCCC2)n1 +CS(=O)(=O)Nc1cc2c3c(c1)CC(=O)N3CCC2 +CCCCN(CCO)C(=O)c1n[nH]c(CC)c1N +CC(=O)Nc1cccc(NC(=O)CCSc2ccc(Cl)cc2)c1 +CN1CCc2c(c(-c3cccc(N)c3)nn2-c2nccs2)C1 +CCCCc1ccc(CC(=O)N2CCCC2C(N)=O)cc1 +COc1ccc2sc(N3CCOCC3)nc2c1 +CC(C)Oc1ccc(C(=O)Nc2ccc(F)c(C#N)c2)cn1 +CC(C)c1nc2ccccc2n1CC(=O)N1CCCCCC1 +Cn1c(=O)n(C)c2cc(S(=O)(=O)NCc3cccs3)ccc21 +Cc1c(C(C)NC(=O)Nc2ccc(C#N)cc2)cnn1C +CC(=O)Nc1cc(NC(=O)Cc2c(F)cccc2F)ccc1F +Cc1ccc(C)c(OCC(=O)NCCCn2ncccc2=O)c1 +COc1ccccc1CCNC(=O)c1ccc(Nc2ncccn2)cc1 +Cc1ccc(C(=O)NC(C)c2ccccn2)cc1F +Cc1nn(C)c2ncnc(N3CCN4C(=O)CNC(=O)C4C3)c12 +COC(=O)c1c(C)cccc1S(=O)(=O)Nc1ccc(OC)cc1 +Cc1occc1-c1nnc(SCC(=O)Nc2nccs2)n1N +Cc1ccccc1CNC(=O)c1c(C)oc2ccn(C)c(=O)c12 +Cc1nnc(CNC(=O)c2cc(-c3cccs3)[nH]n2)o1 +COc1ccc(CCC(=O)C(C#N)c2nnc3n2CCCCC3)cc1 +COc1ccc(C(NC(=O)CCc2ccco2)C2CC2)cc1 +CCOc1ccc(NS(=O)(=O)c2ccc(OC)cc2OC)cc1 +Nc1nc(N2CCCCCC2)ncc1C(=O)N1CCOCC1 +CCCCNC(=O)c1ccc(CS(=O)(=O)c2ccccc2C)o1 +CCCOc1cccc2c1C(c1cnn(C)c1)NCC2 +c1ccc(-c2csc3ncnc(NCC4CCCO4)c23)cc1 +Cc1ccc(C)c(NC(=O)c2ccc(N(C)S(C)(=O)=O)cc2)c1 +CC1CN(C2(C(=O)NCC3CC3)Cc3ccccc3C2)CC(C)O1 +O=C(NCc1nc2ccc(F)cc2[nH]1)c1ccc(-n2ccnc2)nc1 +Cc1cccc(C(=O)N2CC(C)C(=O)Nc3ccccc32)c1 +CC(Oc1ccccc1)C(=O)Nc1ccccc1C(=O)N(C)C +COc1ccc(C(=O)c2c(N)oc3cccnc23)cc1 +COc1ccc2c(=O)c(C(=O)NCc3cccs3)c[nH]c2c1 +COc1ccc(NC(=O)COc2ccc(CO)cc2Cl)cc1 +O=C(Cc1ccc(OC(F)(F)F)cc1)Nc1nnc2ccccn12 +COc1ccccc1CCN(C)C(=O)c1ccncc1F +COCCNC(=O)Cc1ccc(NC(=O)Nc2ccccc2F)cc1 +Cc1ccc(O)c(C(=O)N2CCN(C(=O)c3ccccc3)CC2)c1 +Nc1cc(S(=O)(=O)NC2CCCCC2)ccc1Cl +O=C(NCC(O)c1ccc(F)cc1)c1cc2ccccc2c(=O)[nH]1 +Cc1cc(=O)[nH]c(NCCN2CC3(CCOC3)CCC2=O)n1 +Cc1nn(CCO)c(C)c1CNc1cccc(C(C)C)c1 +O=C(COc1ccccc1)Nc1nc(-c2cccnc2)cs1 +CCOc1ccnc(N2CCCN(c3nc(CC)ns3)CC2)n1 +Cc1ccc(CNC(=O)CCn2ncc3c(C)cccc32)o1 +O=C(NCC1CC1)C1CCCN(C(=O)NC(C2CC2)C2CC2)C1 +CCC(CNC(=O)c1ccc(CNC(N)=O)cc1)c1ccccc1 +CN1CCOc2ccc(-c3csc(CC#N)n3)cc21 +Cc1cc(NC(=O)NCc2ncc[nH]2)ccc1C(N)=O +CC(C)COc1ncc(CNC(=O)N2CCC(CO)C2)cc1Cl +O=C(CCNC(=O)c1ccoc1)NCc1ccco1 +CCC1CN(C)c2ccccc2CN1C(=O)c1ccc(=O)n(CC)n1 +Cc1cc(=O)c(C(=O)NCCCn2ccc3ccccc32)c[nH]1 +O=C(Cn1[nH]c(=O)c2ccccc2c1=O)N1CCOCC1 +CN(C)C(=O)CN(C)S(=O)(=O)c1ccc2[nH]c(=O)c(=O)[nH]c2c1 +CCSc1cc(C(=O)NCc2ccc(C(=O)NC)cc2)ccn1 +Cc1cc(-n2nc(CC#N)cc2C)ccc1Br +CNc1ncc(S(=O)(=O)NCc2cccnc2)cc1C +COc1cccc(C(=O)c2ccccc2Br)n1 +CCOc1ccc(CNCC(O)c2cccc(O)c2)cc1Cl +CC(NC(=O)C(C)(C)C)C(=O)N1CCN(c2ccc(F)cc2)CC1 +CN(C)C(=O)CN(C)C(=O)C1CC1c1ccc(Br)cc1 +NC(=O)CN1CCc2[nH]nc(-c3cccc(F)c3)c2C1 +O=C1CCC(C(=O)NCC(=O)N2CCCc3ccccc32)CN1 +O=c1[nH]ncc(NCc2cc(F)cc(Br)c2)c1Cl +CC(=O)Nc1ccc(F)c(NC(=O)c2cc(Br)c[nH]2)c1 +COC(=O)C(C)Sc1nnnn1-c1ccc(Cl)cc1 +Nc1cnc(N2CCOCC2)c(Br)c1 +CCCOCC(=O)N1CCOC(c2ccc(Cl)cc2)C1 +O=S(=O)(Nc1ccccc1O)c1ccccc1OC(F)(F)F +CCOCC1CCCN(C(=O)c2ccc(OC)c(OC)c2)C1 +CCCC(=O)N1CCN(Cc2nc(C)cs2)CC1 +CC(C)CC(C)OCCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +Cc1cc(C(=O)NCC(C)N2CCOCC2)c(C)n1C1CC1 +Cc1ncccc1CN1CCOC2(CCc3ccccc32)C1 +Cc1ccc(Br)c(NCc2nnnn2C(C)C)c1 +CCCS(=O)(=O)N1CCC(NC(=O)CCc2cccs2)CC1 +Cc1noc(C)c1CC(=O)Oc1ccccc1Br +CC(Oc1ccc(Cl)cc1)c1ccnn1S(C)(=O)=O +Cc1ncsc1CCN(C)C(=O)CN1C(=O)COc2cccnc21 +O=C(CCCn1c(=O)[nH]c2ccccc2c1=O)NCc1ccccn1 +CCCc1ncc(C(=O)N2CCOCC2C2CC2)s1 +O=C(Cc1ccc(-n2cccc2)cc1)Nc1nccs1 +CCCCc1ccc(C(=O)NCC2CN3CCCC3CO2)cc1 +CC(=O)N1c2ccccc2N(Cc2ccccc2)C(=O)CC1C +O=C(NCc1ccc(F)cc1)c1cccc2ncccc12 +O=C(Cc1ccc[nH]1)Nc1ccc(-n2ccnc2)c(F)c1 +COc1ccccc1NC(=O)CSc1nnnn1-c1ccccc1 +CC1CCN(C(=O)Cn2nnc(-c3cccs3)n2)CC1 +N#CCCN(C1CC1)S(=O)(=O)c1ccc(=O)[nH]c1 +O=C1NCCNc2c1cnc1cc(Br)ccc21 +COc1ccccc1CNC(=O)CCc1c(C)nc2ncnn2c1C +COc1ccc(C(=O)NCc2nnc3n2CCC3)cc1 +Cc1nnc2n1CCN(CC(O)COc1ccc(C#N)cc1)C2 +Cc1ccccc1CS(=O)(=O)c1nccs1 +Cn1nccc1CNC(=O)c1cc(Cl)c2c(c1)OCO2 +CCNC(=O)C(C)NC(=O)CCn1ccc2ccccc21 +COc1ccc(C(O)CNC(=O)c2oc3c(c2C)C(=O)CCC3)cc1 +O=C(Cn1cccn1)NC(Cc1ccccc1)c1nc2ccccc2[nH]1 +COCCOCC(=O)Oc1ccc(Cl)c(Cl)c1 +COCCn1cc(-c2ccc(Br)cc2)nn1 +C=CCCC(=O)NCC(O)c1ccc(C(F)(F)F)cc1 +CCCNC(=O)N(C)Cc1nc(-c2cccc(C)c2)no1 +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)NCCNC(=O)C1CC1 +O=C(c1cc(C2CC2)on1)N1CCN(CC2CC2)c2ccccc21 +COc1ccccc1NC(=O)CSc1nnc2n1CCCCC2 +O=C(Cc1cccnc1)NCc1ccc(-c2ccc(F)cc2)o1 +Cc1csc(NC(=O)c2nccc3cc(N)ccc23)n1 +CC1CCN(C(=O)Cc2csc(NC(=O)C(C)C)n2)C(C)C1 +CN(CCCc1cc(-c2ccccc2)n[nH]1)C(=O)c1cc(Cl)c[nH]1 +Cc1ccc(C(=O)NCc2ccccc2OC(F)(F)F)c(=O)[nH]1 +O=C(CCC(=O)N1CCCC1)Nc1cnn(CCc2ccccc2)c1 +Cc1cccc2c1NC(=O)C2(O)C1CCCCC1=O +COc1ccccc1N(C)C(=O)Cc1noc2ccccc12 +CCN(CC(=O)Nc1cc(N)ccc1Cl)c1ccccc1 +Cc1cccc(OCc2nn3cc(N)nc3s2)c1 +O=C(Cn1cnc2c(oc3ccccc32)c1=O)OCC1CC1 +Cc1cc(OCC(=O)Nc2c[nH]ccc2=O)c(C(C)C)cc1Cl +Cc1ccncc1NC(=O)N(C)Cc1cccc(OC(F)(F)F)c1 +CCN(CC1CC1)C(=O)Nc1ccc(C(=O)NC(C)C)cc1C +NC(=O)N1CCOC2(CCCC2COc2cccnc2)C1 +CN(C(=O)c1ccc(N2CCCCCC2)nc1)C1CCCCC1 +CCOC(=O)C1CCN(S(=O)(=O)c2cnn(CC)c2)CC1 +COCCNC(=O)CN(C)c1cc(N)cc(F)c1 +CCCc1c(C)nc2ncnn2c1NCc1cccs1 +CC(C)Oc1ccc(CNC(=O)NCC(C)(C)c2ccncc2)cc1 +CC1CCCN(C(=O)NCc2ccc(-n3cccn3)cc2)CC1 +Cc1ccc(-c2c(C)sc3ncnc(NCCCO)c23)cc1 +COc1ccc(S(=O)(=O)NC(C)C(N)=O)cc1C +CC(C)NC(=O)c1ccc(N2CCN(CCO)CC2)nc1 +Cc1ccc(NC(=O)c2cccc(OCC(F)F)n2)c(O)c1 +CCCOc1cccc(NC(=O)N2CCCC2CN2CCOCC2)c1 +CC(=O)c1ccccc1NCCOc1ccc(C#N)cc1 +CC(C)=CC1C(C(=O)Nc2ccc3c(c2)NC(=O)CO3)C1(C)C +COc1ccccc1CCC(=O)NCc1ccc(-n2ccnc2)cc1 +CC1CC1COC(=O)Cn1c2ccccc2c(=O)c2ccccc21 +Cc1cccc(Nc2cc(C3CCCN3S(C)(=O)=O)ccn2)n1 +CC(Nc1ccc(N2CCOC2=O)cc1)c1nc(C(C)(C)C)no1 +Cc1ccc(S(=O)(=O)NCCC2CCCO2)s1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)Cc1c(C)nc(C)[nH]c1=O +O=C(CNC(=O)c1ccc2[nH]cnc2c1)Nc1ccc(F)cc1 +COC(=O)N1CCN(CC(=O)Nc2cc(C)on2)CC1 +Cc1nn(-c2ccc(NC(=O)C3CC(=O)N(C)C3)cn2)c(C)c1Cl +CC(c1ccncc1)N(C)C(=O)COc1ccc2ccccc2c1 +O=c1[nH]ccc2nc3ncnn3c(-c3cccc(Cl)c3)c12 +CC1CCCCN1C(=O)C1CC(=O)N(c2ccc3c(c2)OCCO3)C1 +COCCNC(=O)N1CCN(c2cccc(C)c2)CC1 +CC(C)Sc1ccc(C(=O)NC2CCCNC2=O)cc1 +Cc1cc(C(=O)N2CCCC(C(N)=O)C2)ccc1N +Cc1cc(=O)[nH]c(-c2ccc(NC(=O)Cc3ccc(C)s3)cc2)n1 +Cc1ccccc1OCCN(C)C(=O)Cc1ccc[nH]1 +CCOc1ncccc1C(=O)Nc1ccc(N2CCOCC2)nc1 +CCC(C)NS(=O)(=O)c1ccc(C(=O)Nc2cccnc2)cc1 +CC1Oc2ccc(NC(=O)c3cccc(C#N)c3)cc2NC1=O +COCc1cccc(C(=O)Nc2ccc(OCC(F)(F)F)nc2)c1 +COc1ccc(OC(C)C(=O)Nc2nc(C)cs2)cc1 +O=C(CC1CCCC1)NC1CCN(C(=O)Nc2cccc(F)c2)CC1 +COc1ccccc1CCCC(=O)N1CCC(O)CC1 +CC(=O)N1CCC(C(=O)Nc2cccc(F)c2)CC1 +C=CC(C)Sc1nncn1-c1cccc(NC(C)=O)c1 +COC(=O)C(C)CN(C)C(=O)c1cc(-c2cccc(Cl)c2)no1 +CCNC(=O)CN1CCN(C(=O)Nc2cccc(C)c2C)CC1 +C#CCN1CCN(C(=O)NCC(C)c2ccsc2)CC1 +Cc1cc(C(=O)Nc2cccn(C)c2=O)c(C)n1C1CCCCC1 +O=C(Nc1ccc2c(c1)OCO2)c1ccccc1O +CC(Nc1ccc2ccccc2c1)c1nncn1C +CC(C)(C)C(NC(=O)Nc1cc(F)ccc1-n1cccn1)C(N)=O +Cc1cc(C(N)=O)ccc1NC(=O)c1ccc(=O)[nH]c1 +COc1ccccc1N1CCN(CC(=O)NCC(C)O)C1=O +CC(CNc1ccc(C(=O)Nc2nncs2)cn1)c1cccs1 +COc1ccc(C2CCN(S(=O)(=O)c3c(C)nn(C)c3C)C2)cc1 +Cn1cnnc1SC1CCCc2ccccc2C1=O +N#Cc1ccc(NC(=O)c2ccc(C(F)(F)F)cc2)cc1 +CN(CCC#N)C(=O)C1(c2ccc(Cl)cc2)CC1 +COc1cccc(C(CNC(=O)c2ccccc2OC)OC)c1 +CCc1cccc(C)c1NC(=O)CSc1nnc(C(C)(C)C)n1N +Cn1c(=O)n(C)c2cc(NC(=O)COc3ccc(F)cc3)ccc21 +COc1cccc(C(=O)NC2CCN(C(=O)C3CCCCC3)C2)c1F +CCCOc1ccc(COC(=O)c2ccc(C)[nH]c2=O)cc1 +Cc1ccccc1-n1ccnc1SCC(=O)NC1(C#N)CCCC1 +Cc1nn(C)c(N)c1S(=O)(=O)NCCc1ccccc1 +CCN(C(=O)c1cnn(C)c1C)C(C)c1cc2ccccc2o1 +COc1ccc2cc(C(=O)N(C)CCC#N)[nH]c2c1 +O=C(c1cccs1)C1NCCc2cc3c(cc21)OCO3 +N#Cc1ccccc1OCC(=O)NCC(F)(F)F +COc1ccccc1CC(C)N(C)Cc1c[nH]nc1C +CC(C1CC1)N(C)C(=O)NCc1ccc(C#N)cc1 +CC(C)n1c(N)nnc1SCC#Cc1ccccc1 +CCOC(=O)c1nsc(C(=O)Nc2cc(C)ccn2)c1N +CCOC(=O)c1ccc(NCc2cccnc2)c(N)c1 +CC(C)Oc1cc(C(=O)N(C)C)c(OC2CC2)cn1 +Cc1cc(C)n(-c2ccc(C(=O)NCCC(C)C)cc2)n1 +CCN1C(=O)Cc2c(C)nc(-c3ccc(F)cc3)nc21 +COC(C)C(=O)NCc1ccnc(OCC(F)(F)F)c1 +Cc1c(C(=O)N(C)Cc2cc(Br)cn2C)cnn1C +CC(C)(C)OC(=O)N1CCCC(S(=O)c2ncc(F)cn2)C1 +Cc1nn(Cc2ccccc2)c(C)c1C1NC(=O)c2cccnc2N1 +O=C(NCc1ccoc1)c1ccc(-n2cccn2)nc1 +Nn1c(SCC(=O)NC2CCCCC2)nnc1-c1ccccc1F +CC(C)COC(=O)c1ccc(NC(=O)CC#N)cc1 +COc1ccc(-c2onc(C)c2N)c(Cl)c1Cl +CCOC(=O)N1CCC(NS(=O)(=O)C2CC2)CC1 +COc1ccc(OC(C)C(=O)N(CC(F)F)C2CC2)cc1 +CC(CC(O)c1ccccc1)NC(=O)c1ccc(Cl)cn1 +CC(NC(=O)c1ccc[nH]c1=O)c1ccc(Br)cc1 +CCCNC(=O)CSc1nc2ccccc2c(=O)n1CCC +O=C(c1cn[nH]n1)N1CCC(Oc2ccccc2)CC1 +Cc1ccc(CC(=O)NCC(=O)N2CCCc3ccccc32)s1 +COc1ccc(C)cc1NC(=O)CNC(=O)c1ccc(=O)[nH]c1 +O=C(Nc1ccn(Cc2ccccc2)n1)c1cc2ccccc2oc1=O +COc1cc(C)c(S(=O)(=O)N2CCC(C(N)=O)CC2)cc1C +O=C(NCc1coc(-c2ccccc2)n1)NC1COc2ccccc21 +CCCC(=O)N1CCCC1C(=O)Nc1ccc(N2CCCCC2)cn1 +C=CCNC(=O)NCC1CCN(c2cccc(Br)c2)C1 +O=C(NCCCO)Nc1cnn(Cc2ccc(Cl)cc2)c1 +COc1ccc(OCCNC(=O)c2ccccn2)cc1 +CCCCC(=O)NCC1COC2(CCCCC2)O1 +Cc1n[nH]c(C)c1NC(=O)COc1ccc2oc3c(c2c1)CCCC3 +Cc1nn(C)c(C)c1NC(=O)Cn1c(=O)oc2cc(Cl)ccc21 +O=C(c1ccc2c(c1)CCN2C(=O)C1CC1)N1CCc2ccccc21 +CCNC(=O)CCc1csc(NC(=O)Nc2ccccc2)n1 +O=S(=O)(NCCc1cccnc1)c1ccc2c(c1)OCCO2 +Cc1cc(C)cc(NS(=O)(=O)c2cc(-c3ccno3)oc2C)c1 +CNC(=O)NCC(=O)Nc1cccc(Cl)c1OC +CCC(c1c(O)cc(C)n(CC)c1=O)c1c(O)cc(C)n(CC)c1=O +CC1CC(C)CN(C(=O)C2CCN(C(=O)C(C)(C)C)CC2)C1 +CNC(=O)c1ccc(C2CN(c3cncnc3)CCO2)nc1 +CS(=O)(=O)N(CCCO)c1cccc(Cl)c1Cl +CC(OC(=O)CCN1CCCC1=O)c1cnc2ccccc2c1 +CCc1cc(N(C)Cc2ccnc(C)c2)n2nc(C)c(C)c2n1 +CCOC(=O)c1cc(NC(=O)Nc2cccnc2)c(C)nc1C +CC(C#N)Cn1c(-c2cccc(N)c2)nc2ccccc21 +Cc1cccc(C)c1NCC(=O)NC(C)c1ccccc1 +Cc1ccc(NCC(=O)Nc2c(C)cccc2C)cc1 +COc1ccc(F)c(NC(=O)C(C)Sc2nncn2C)c1 +O=C(Nc1ccc(F)cc1F)N1CCN(c2cccc(O)c2)CC1 +Cc1ccc(-c2ncc(C(=O)Nc3ncccn3)c(N)n2)cc1 +COc1ccc(C(C)N(C)c2ncnc3c2cnn3C)cc1 +Cc1cc(C(O)C(=O)NCc2ccncc2)ccc1F +COCCCn1ccc(NC(=O)Nc2cccc(NC(C)=O)c2)n1 +CC(=O)N1CCN(C(=O)c2oc3ccccc3c2COC(C)C)CC1 +Cc1nn(-c2ccccn2)c(C)c1N1CCN(S(C)(=O)=O)CC1 +COc1cc(C(=O)NC2c3ccccc3CC2O)cc(Cl)c1OC +CC(C)c1ccc(CN2CCOCS2(=O)=O)cc1 +COc1ccccc1-n1ccn(Cc2cccc(F)c2)c(=O)c1=O +CCCc1nc(C(=O)NCCc2nc(C)c(C)s2)cs1 +CCC(C)NC(=O)C(C)NC(=O)CCc1ccsc1 +CCOc1ccccc1C(=O)N1CCCC1C(=O)NCC(C)C +CC(C)c1cc(C(=O)N2CCOC(C)(C)C2)c2cnn(C(C)C)c2n1 +NC(C(=O)OCc1ccc(F)cc1)c1ccccc1 +CC(C)Cc1ccc(C(=O)CCc2nccs2)cc1 +NC(=O)c1ccccc1COC(=O)Cc1c(F)cccc1F +CC1(C)COC(c2ccccc2)CN1Cc1cnc2cnccn12 +COc1cc(C(=O)Nc2ccnc3ccccc23)cc(OC)c1OC +Cc1cnn(CCC(=O)NCC(c2ccccc2)c2ccccc2)c1 +CC(C)c1nc(C2CCCN(c3ncccn3)C2)no1 +Cc1noc(C)c1CCCNC(=O)Nc1cccc(S(C)=O)c1 +COC(=O)Cc1nn(C)c2c1nnc1nc(Cc3ccccc3)nn12 +Cc1ncsc1CCOC(=O)c1csc(-c2cnccn2)n1 +Cc1nc(CNC(=O)c2cn(C)nc2C(C)(C)C)no1 +Cc1ccc2oc(=O)cc(CNC(=O)c3ccco3)c2c1 +CC(C)Oc1ccc(C(=O)N2C3CCC2COC3)cc1 +O=C(CCC(O)c1cccs1)N1CCCCC1 +O=C(c1ccc(-c2ccccc2)cc1)N1CCCS1(=O)=O +Cc1ccc(S(=O)(=O)Nc2cn[nH]c2)c(Br)c1 +CC(Sc1nncn1C(C)C)C(=O)Nc1ccc(F)cc1 +Cc1cc(C)n(C)c(=O)c1C(=O)NCC1CCCO1 +O=C(COc1ccccc1)Nc1nnc(Cc2ccc(F)cc2)o1 +CCSc1ccccc1C(=O)NCC(C)(O)COC +Cc1ccc(NC(=O)CNc2ccc(C(N)=O)c(C)c2)c(Cl)c1 +COc1ccc(Cl)cc1COC(=O)c1c(C)noc1C +CCCCNC(=O)C(C)NC(=O)c1ccc(Cl)cc1 +Cc1cc(NC(=O)c2nc3nc(C)cc(C)n3n2)c2ncccc2c1 +COC(=O)Nc1ccc(NC(=O)NCc2ccc3c(c2)CCC3)cc1 +CCN(CC)C(=O)c1c(C)nc(N)nc1CCc1ccccc1Cl +Cc1nn(C)c(C)c1OS(=O)(=O)c1ccccc1 +Cc1cccc(-c2noc(CNC(=O)c3ccccc3C)n2)c1 +O=C(CC1CC1)N1CCC2(CC1)CN(c1ccsc1)C(=O)CO2 +CCCn1c(CN2CCCC3(C2)OCCO3)nc2ccccc21 +Cc1ccc(-n2cc(C)cn2)c(NCc2cscn2)c1 +COC(=O)c1c(CC(=O)N(C)c2ccc(C)cc2)[nH]c(C(C)=O)c1C +CCn1cc(Cl)c(C(=O)Nc2ccc(Cn3cccn3)cc2)n1 +Cc1cc(F)ccc1NC(=O)N(C)Cc1ccoc1C +Cc1nnc(NC(=O)CCCc2nnc3ccccn23)s1 +CCS(=O)(=O)NCCCNC(=O)c1c(C)nn(C)c1C +CCCc1cc(=O)[nH]c(SCC(=O)N2CCc3ccccc3C2)n1 +O=C(c1cnns1)N1CCC(Cc2ccccc2)C1 +Cc1ccc(Oc2ccc(-c3nc(N)nc(N)n3)cc2)cc1 +CC(C)C(=O)c1cc2c(cc1NC(=O)c1ccccc1)OCCO2 +CCC(=O)Nc1ccc(CC(=O)N2CCOCC2)cc1 +CCn1c(=O)c2ccccc2n(CC(=O)OCc2cc(C)no2)c1=O +O=C(NCCCNC(=O)C1CCC1)NCc1nc2ccccc2s1 +COc1ccc(S(=O)(=O)NCCc2c[nH]c3ccccc23)cc1F +CN(C)C(=O)C1CCCN(C(=O)c2ccccc2O)C1 +COc1ccc(NC(=O)c2ccc(OC)c(Br)c2)cn1 +Cc1c2cn[nH]c(=O)c2c(C)n1Cc1cccs1 +Cc1ccccc1NC(=O)C(C)N(c1ccccc1)S(C)(=O)=O +Cc1ccc(C(=O)NCc2nc(-c3ccccc3)no2)c(C)c1 +CC(O)CNC(=O)c1sccc1Br +CN(C)c1ccc(NC(=O)CN2CCCCC2=O)cn1 +Cn1cc(CNC(=O)N2CCNC(=O)C2)c(-c2ccccc2)n1 +Cc1nonc1NC(=O)COc1ccc(Cl)cc1Cl +CC1(C)CCC(CNC(=O)c2nccnc2N)CC1 +CCOC(=O)C1=C(C(C)C)NC(=O)NC1c1ccc(OC)c(O)c1 +O=C1CC(C(=O)N2CCCCC2CCc2ccccc2)CN1 +COc1nn(C)cc1C(=O)NCCn1ccnc1-c1ncccn1 +COc1ccc(S(=O)(=O)NC(C)(C)CO)cc1C +Cc1ccc(C(=O)NCCCNS(C)(=O)=O)s1 +CCc1c(C(=O)N(CC)CCO)cnn1-c1ccccn1 +CCN(CC)S(=O)(=O)c1cc(C)c(C)c(N)c1 +Cc1nc(N2CCCC(C(=O)NCC3CC3)C2)c2cc[nH]c2n1 +CC(Oc1ccc(C#N)cc1)C(=O)NCc1cccc(-n2cccn2)c1 +Cc1ccc(CNC(=O)c2c(C)noc2C(C)C)s1 +Cc1cc(C(=O)Nc2ccccc2C)c2cnn(C(C)C)c2n1 +Cc1nn(C)c(C)c1CCC(=O)Nc1cc(C#N)cn1C(C)(C)C +Cc1cnn(CCC(=O)NC(C)c2cccc3ccccc23)c1 +Cc1nc2c(cnn2C(C)C)cc1C(=O)N1Cc2ccccc2C1 +NC(=O)NCc1ccc(-c2nc(-c3ccc(F)c(F)c3)no2)cc1 +Cc1cccc(C(=O)N(C)Cc2ccccc2F)c1O +c1cc2c(cc1OCc1nc(C3CC3)no1)OCO2 +O=C1CCc2cc(NC(=O)Nc3cccs3)ccc2N1 +CCc1noc(C)c1C(=O)N1CCC(C(=O)OC)CC1 +CC(C)Cc1cc(CNC(=O)Cn2c(=O)oc3ccccc32)no1 +Clc1ccc(CN2CC(c3nc(-c4cnccn4)no3)C2)cc1 +Cc1nn(C)c(C)c1S(=O)(=O)Nc1cn[nH]c1 +CC(C)C(NC(=O)COc1ccccc1)c1ccc2c(c1)OCCO2 +CCc1cc2c(SCCC#N)nc(C)nc2s1 +CCOc1ccccc1NC(=O)N1CCOCC1 +COc1ccc(CC(C)CNC(=O)c2n[nH]c3c2CCC3)cc1 +COc1cccc(C(=O)NC(O)C(Cl)(Cl)Cl)c1 +CCOCC(=O)N1CCC(S(=O)(=O)c2ccccc2)C1 +CC(C(=O)NCc1cccs1)S(=O)(=O)c1ccccn1 +Cc1ccc(NC(=O)c2c[nH]c3cc(C(F)(F)F)ccc3c2=O)cc1 +CCOC(=O)CCC(C)NC(=O)Nc1cccc(Cl)c1C +CCC(C)(C)NS(=O)(=O)c1cc(F)c(F)cc1F +Cc1c(C(=O)Nc2ccccc2OCC2CC2)cnn1-c1ccccn1 +CC(CC#N)NC(=O)c1ccccc1Br +CCc1ccccc1OCCC(=O)NC(C)(C)CO +Cc1cc(Br)cc(C)c1NCc1ccccn1 +COc1cc[nH]c(=NS(=O)(=O)c2cc(F)ccc2F)c1 +CCc1noc(CC)c1CNC(=O)c1sccc1OC(F)F +O=C(c1cccc(-n2ccnc2)c1)N1CCC(OC2CCCC2)CC1 +COc1ccc(C(=O)Nc2ccccc2-n2cccn2)nn1 +CCc1cnc(CN2CCCC(c3noc(CC)n3)C2)o1 +CCC(Cc1cc(OC)c(OC)c(OC)c1)C(C)=O +COc1cc(OC)cc(-n2ccc3c(nnc4nc(C)nn43)c2=O)c1 +CNC(=O)CCc1nc2sc3c(c2c(=O)[nH]1)CCC(C)C3 +C=C(C)CSc1nc(C2CC2)n(-c2ccccc2)n1 +COC(=O)C(C)CNC(=O)Nc1cncc(C)c1 +C#CC(OC(=O)c1cc(C)n(C(C)C)c1C)C1CC1 +O=C1CC(c2ccccc2)=NC(c2ccccc2CN2CCOCC2)=N1 +CC(C)(C)C(=O)NCCNC(=O)N1CCc2c(F)ccc(F)c2C1 +CC(=O)Nc1ccc2c(c1)C(C1CC(=O)C1)NCC2 +Cc1occc1C(=O)N(CCC#N)Cc1ccco1 +CC(C)CN(CC(F)(F)F)C(=O)Cn1nnnc1C(C)(C)C +CCn1c(CNS(=O)(=O)c2ccc(Cl)cc2)nc2ccccc21 +Cc1ccsc1C(=O)Oc1cccc(S(C)(=O)=O)c1 +COC(=O)COc1ncnc2ccc(Br)cc12 +O=C(NCc1ccc(F)cc1)c1nnc(Cn2ccnc2)s1 +O=S(=O)(CC1CCOCC1)c1cc2c(cc1Cl)OCCO2 +COc1ccc(C(=O)Nc2c(C)ccc(N)c2C)c(O)c1 +COC(=O)c1ccc(NC(=O)CC(c2ccco2)n2cccc2)cc1 +CC(CN1CCOCC1)NC(=O)c1ccc(S(C)(=O)=O)cc1 +CC1CN(C(=O)c2cn3cccnc3n2)c2ccccc21 +c1cncc(Oc2ccc(-c3nc(-c4ccncc4)no3)cc2)c1 +COc1ccc(NC(=O)CCC(C#N)c2cccnc2)cc1 +Cc1ccc(C(=O)CSc2nc(N)cc(N)n2)cc1 +CC(C)(C)NC(=O)NC1CCCN(Cc2ccccc2)C1=O +O=C(Nc1ccc2ncccc2c1)c1ccc(-n2ccnc2)nc1 +Cc1cccc(CN(Cc2ccccn2)Cc2cncs2)c1 +COc1ccccc1CNC(=O)c1cnc2sccn2c1=O +O=C(NCCc1ccccn1)c1c[nH]c2ccc(F)cc2c1=O +COC(=O)C1CCN(C(=O)Cc2ccc(OC)c(OC)c2)CC1 +CCCN(C)C(=O)c1ccc2c(c1)CCN2S(C)(=O)=O +FC(F)CN1CCN(Cc2noc(C3CC3)n2)CC1 +COCc1nc(CN2CCOCC2)sc1C(C)(C)O +Cc1cc(=O)oc2cc(OS(C)(=O)=O)ccc12 +COc1ccc(C(=O)c2oc3ccccc3c2N)cc1OC +CCc1nnc(NC(=O)c2ccccc2-n2cnnn2)s1 +Cc1cccc(CNC(=O)NC(C)C(=O)N2CCCCC2C)n1 +Cc1cnn(CCC(=O)N(Cc2ccccc2)C(C)C2CC2)c1 +O=C(Cc1c[nH]c2ccccc12)Nc1ccc(-n2cccc2)cc1 +Cc1cc(C)c(C(=O)CSc2n[nH]c(=O)n2C2CC2)c(C)c1 +CC(=O)Nc1ccc(OC(C)C(=O)N2c3ccccc3CC2C)cc1 +Cc1cccc(C(=O)NCCNC(=O)c2ccco2)c1C +COC(=O)c1cnn(-c2ccc(OC)cc2OC)c1N +CC(=O)c1ccc(S(C)(=O)=O)c(NC2CC=CC2)c1 +CCN(CC)C(=O)N1CCN(c2ccc(Cl)cc2)CC1 +O=C(NCCSc1ncn[nH]1)C1COc2ccccc2C1 +Cc1ccc(OCCN2CCN(Cc3nnc(C)n3C)CC2)cc1 +CNS(=O)(=O)c1cccc(CNC(=O)N2CCOCC2)c1 +CCC(C)C(=O)Nc1cccc(OCC(=O)OC)c1 +CC(C)NC(=O)NC(C)c1ccc2c(c1)OCO2 +Cc1cc(Br)c2c(c1)c(=O)oc(=O)n2CC(N)=O +CC(C)(CO)Nc1ccc(NC(=O)COc2ccc(Cl)cc2)cn1 +Cc1ccc(OCC(=O)NCc2cccnc2)cc1C +CCc1cc(=O)oc2cc(C)cc(OC(C)C(=O)NCCCO)c12 +O=C1CN(c2ccc(NC(=O)CC3C=CCC3)cn2)CCN1 +O=C(NCCc1csc(N2CCCC2)n1)Nc1ccccc1F +Cc1nc2ccccc2nc1SCCC(=O)Nc1cccc(C#N)c1 +CCc1cnc(CCNC(=O)NC2CC(=O)N(C3CC3)C2)s1 +CC(=O)OC1C(C(O)CO)OC2OC(C)(C)OC21 +CC(C(=O)OCCNc1cccnn1)c1cccs1 +O=C(CCSc1ccccn1)NCC1(c2ccc(F)cc2F)CC1 +Cc1cccc2sc(NC(=O)C3CCOCC3)nc12 +c1csc(-c2n[nH]cc2CN2CCOC(c3cccs3)C2)c1 +Nc1cccnc1Nc1cccc2c(O)cccc12 +CCN(CCNC(=O)C1CCCN(C(C)=O)C1)c1ccccc1C +COc1ccc(NC(=O)CN(C)C(=O)c2cccc(N(C)C)c2)cc1 +N#CCOc1cccc(CC(=O)NC2(c3ccccc3F)CC2)c1 +COc1ccc(C(O)C(C)NC(=O)CSc2ccccc2F)cc1 +Cc1cccc(-c2nc3c4c5c(sc4ncn3n2)CN(C)CC5)c1 +CCC(C)n1ncc(C(=O)Nc2ccc(C(N)=O)cc2F)c1C1CC1 +COc1ccc(C2=Nc3ncnn3C(c3cccs3)C2)cc1OC +CC(C)(C)C(=O)NCC(=O)Nc1ccc(C(N)=O)cc1 +Cc1csc(SCc2cc(-c3ccco3)on2)n1 +Cc1csc(NC(=O)NC(C)c2cccc(OC(C)C)c2)n1 +CCCC1CN(C(=O)c2ccoc2C)CC1NC(C)=O +COC(=O)CC1CCCCN1C(=O)c1ccc(Cl)cc1Cl +Cc1c(C)n(Cc2ccccn2)c2ncnc(NCc3ccncc3)c12 +CN(CC(=O)NCc1ccco1)S(=O)(=O)c1ccc(Cl)cc1 +Cc1nc(-c2cc(C(=O)N(C)Cc3ccccc3C)n(C)c2)cs1 +O=C(Cn1ncc(-c2ccccc2)nc1=O)Nc1ccc(Cl)cc1 +Cn1c(=O)c2nc(-c3ccccc3)c(=O)n(C)c2n(C)c1=O +Cc1csc(SC(C)C(=O)Nc2ccc(Cl)cn2)n1 +Cc1cc(C(C)NC(=O)COc2ccc(C#N)cc2)c(C)o1 +COCCCC(=O)NC(C)c1nc2ccccc2[nH]1 +CC(C)N(C)S(=O)(=O)c1cccc(C(=O)NCc2cccnc2)c1 +COc1cc(C)c(C)cc1C(O)C(=O)N1CCNCC1 +Cc1c(C(=O)N2CCCC(CC(C)C)C2)cnn1-c1ccncc1 +CCc1nc(NC(=O)NC(c2ccccc2)c2ccco2)nn1C +O=C(NCC(O)c1cccc(Cl)c1)c1ccc(F)cc1 +Cc1ccc(OCC#CCNC(=O)c2c(F)cccc2F)cn1 +CC(C)N=c1ccccn1C(=O)CN1C(=O)COc2ccccc21 +O=C(CSc1ccc(F)cc1F)Nc1cccnc1 +Cc1cc(-c2csc(NC(=O)Cc3ccccc3F)n2)c(C)n1C +O=C(c1ccc(-n2cccc2)cc1)N1CCC(Oc2cnccn2)CC1 +O=C(NCc1ccccc1F)Nc1ccc(-c2csnn2)cc1 +CCOc1ccc(S(=O)(=O)NCC(O)c2cccs2)cc1F +CCN(C)C(=O)CSc1nc(Cc2ccccc2)c(C)[nH]1 +COc1ccc(C(=O)Cn2ccnc2)cc1C(C)(C)C +Cc1ccn2cc(C(=O)N3CCOC4CCCCC43)nc2c1 +CCN(CC1COc2ccccc2O1)C(=O)CCNC(C)=O +COc1ccc(NC(=O)c2cccc(C)c2)cc1N +COc1cccc(CNC(=O)NCc2cc3ccccc3o2)c1OC +O=C(Nc1ccc(-n2ccnc2)nc1)Nc1ccc(-n2ccnc2)nc1 +CCOC(=O)CCNc1ccc(Cl)cc1Cl +CN(C(=O)C(C#N)Cc1cccnc1)c1ccccc1 +CCCC(=O)NCC(=O)Nc1cccn(Cc2ccc(F)cc2)c1=O +Cc1cccc(OCCN2CCN(c3cnccn3)CC2)c1 +O=C(OCC(=O)N1CCC(Cc2ccccc2)CC1)c1ccncc1 +CCn1nc(C)c(Cl)c1C(=O)NCCc1ccc(OC)cc1 +COC(=O)C1CCN(C(=O)CC(C)c2ccccc2)CC1 +CC(C)C(NC(=O)c1ccccc1Cl)C(=O)OCC(F)F +O=C(C1CCCO1)N1CCCC1c1nc(-c2ccncc2)n[nH]1 +CC(C)(C)OC(=O)N1CCCC1C(=O)NCC1CCCO1 +Cc1c(CO)nnn1Cc1ccc(C(C)(C)C)cc1 +CC(NC(=O)COC(=O)c1cc(F)ccc1F)c1ccccc1 +COCCCNC(=O)Nc1ccccc1-n1cccn1 +CCCNC(=O)c1snc(-c2ccccn2)c1NC(=O)C1CC1 +COc1ccc(NC(=O)NCc2ccnc(OC3CCC3)c2)cc1C +O=C(NCC(F)(F)F)c1c[nH]nc1-c1ccccc1F +CCCn1c(CNCc2cccc(C(N)=O)c2)nc2ccccc21 +CCn1cc(CCNS(=O)(=O)c2cccc(C)c2)c2cccnc21 +CCn1cc(NC(=O)CCc2nc3cc(Cl)ccc3s2)cn1 +CC(=O)Nc1cccc(Nc2cc(C)nc(C)n2)c1 +O=C(OCc1ccc2c(c1)OCO2)C1CCOCC1 +Cc1cccn2cc(C(=O)NCCN3CCOCC3)nc12 +COc1ccc(Cl)cc1C(=O)CCc1nc(C)cs1 +COc1ccc(CC(=O)OCC(=O)Nc2cccc(C#N)c2)cc1 +CC(C)(CNC(=O)c1ccc(N2CCCC2)c(F)c1)c1ccncc1 +CC(=O)N1CCCC2(C1)N=C(c1ccccc1)C(=O)N2 +c1ccc(OC2CCCC2)c(CN2CCOC(c3nccs3)C2)c1 +Cc1noc(NC(=O)C2CC(c3ccccc3)C2)n1 +O=C(CN1CCOc2ccccc21)Nc1nncs1 +Cc1ocnc1CNS(=O)(=O)N1CCC(C(C)(C)C)CC1 +CCOC(=O)CS(=O)(=O)c1ccc(OC)cc1 +COCCn1nc(C)c(NC(=O)Cc2c(F)cccc2F)c1C +FC(F)(F)c1ccc(NCCc2nnc3ccccn23)nc1 +Cc1n[nH]c(SCC(=O)N(C)C(C)c2ccccc2Cl)n1 +CCC(C)C(O)CNS(=O)(=O)N1CCC(C(C)(C)C)CC1 +COc1cc(C)c(C)cc1S(=O)(=O)N1CCCCCC1 +Fc1cc2c(c(F)c1F)CCNC2c1ccccn1 +Cc1ccc(C)c(S(=O)(=O)N(CC(N)=O)Cc2ccccc2)c1 +CCOC(=O)c1cncc(-c2cc3ccccc3o2)c1 +Cc1nnc(CN(C)C(=O)Nc2cccc(C)c2C)o1 +CCNC(=O)Nc1cccc(CS(=O)(=O)NC(C)CC)c1 +COc1cccc(-c2nc(C)c(C(C)(C)O)s2)c1 +CCNC(=O)c1ccc(C)c(NC(=O)N(CC)CCO)c1 +COc1ccc(CNC(=O)c2oc3c(c2C)-c2[nH]ncc2CC3)cc1 +CCCn1nc(C(=O)NCCCc2ccccc2)ccc1=O +CCCc1nnc(N2CC3CCC(C2)N(CCOC)C3)s1 +COC(C)C(=O)N1CCCCC1CCc1ccccc1 +O=C(NCCc1csc(-n2cccn2)n1)C1CC=CCC1 +CC(=O)Nc1cc(Cl)ccc1NC(=O)c1ccc(F)cc1 +CC(=O)Nc1cccc(NC(=O)Nc2ccccc2CC(N)=O)c1 +Nc1ccccc1OCCn1c(=O)oc2ccc(Cl)cc21 +Cc1cc(C)c(NC(=O)c2ccc(F)cc2F)c(C)n1 +Cc1occc1C(=O)NCC(=O)Nc1ccc(-c2csnn2)cc1 +COCCNC(=O)Nc1ccccc1CC(=O)N(C)C +CC1NCCc2cc(OC(F)F)c(OC(F)F)cc21 +CCCOc1cccc(C(=O)N(C(C)C)C2CCOCC2)c1 +N#CCc1ccc(NC(=O)c2ccc(-c3cscn3)cc2)cc1 +CCN(CC)C(=O)c1ccc(-c2ccco2)[nH]c1=O +O=C(CCn1cncn1)NCCOc1cccc(Cl)c1 +C#CCNC(C)(C(=O)OC)c1cc(C)ccc1OC +COCCC1(O)CCN(C(=O)c2ccccc2-c2nc[nH]n2)CC1C +CC(NC(=O)Nc1cc(N2CCCS2(=O)=O)ccc1F)C1CC1 +Cc1ccccc1C(=O)Nc1cc(Cl)ccc1N +CCn1cnnc1CNS(=O)(=O)Cc1ccccc1 +COCCCNC(=O)COc1ccc2nc3n(c(=O)c2c1)CCC3 +Nc1cccc(OCC(=O)Nc2ccccc2C(F)(F)F)c1 +Cc1cccc(NC(=O)N(C)CCOCC2CC2)c1 +Cc1csc(SC(C(=O)NC2CCCC2)C(C)C)n1 +Cc1ccc(CNC(=O)NCCCn2nc3n(c2=O)CCCC3)cn1 +O=C(c1ccccc1)N1CCCC(OCc2ccccc2)C1 +CCOC(=O)N1CCC(S(=O)(=O)N2CC(C)OC(C)C2)CC1 +CCC(NCc1cccnc1)C(=O)c1ccc2c(c1)CCN2 +Cn1cc(C(=O)NCc2ccc(C#N)cc2F)c(C(C)(C)C)n1 +COCCNC(=O)c1cc(=O)c(OCc2ccccc2)co1 +COCCCC1CCCN(C(=O)Cc2ccc(O)c(Cl)c2)C1 +CCNC(=O)NC1CCC(OC(=O)c2n[nH]c3ccc(C)cc23)CC1 +CN(Cc1ccccc1)C(=O)c1ccccc1CC#N +CC(CO)NS(=O)(=O)c1ccc2c(c1)CCC2 +CCC(Oc1cc(-c2nccs2)ccc1N)C(=O)OC +N#Cc1ccccc1NC(=O)CCC(=O)c1ccc(F)c(F)c1 +CN1CCOC(C(=O)NC2CCOC2c2ccc(Cl)c(F)c2)C1 +Cc1oc(C(=O)NCCO)cc1S(=O)(=O)N1CCCC1 +CC1COC2(CCCN(C(=O)c3ccc4ccccc4n3)C2)C1 +N#Cc1cccc(NC(=O)CNC(=O)c2ccco2)c1 +CC(CCc1ccccc1)NC(=O)Cc1nnc(-c2ccsc2)o1 +Nc1ccc(S(=O)Cc2ccc(F)cc2F)cc1 +COc1ccc(-c2cc(N(C)CC(=O)NC3CCCC3)n[nH]2)cc1 +Cc1nc(C)n(CC(=O)Nc2cccc(C(F)(F)F)c2)n1 +C#CCN1CCN(C(=O)NCCC(=O)NC(C)CC)CC1 +O=C(c1ccc2c(c1)OCO2)N(Cc1cccs1)CC1CCCO1 +CC(CO)NC(=O)c1ccc(-c2ccc(Cl)cc2Cl)o1 +Cc1cc(CNC(=O)c2ccn(-c3cccc(F)c3)n2)c(C)o1 +Cc1cnn(CC2CCCN2C(=O)c2cc(F)cc3[nH]cnc23)c1 +CC(=O)N1CCc2ccc(NS(=O)(=O)c3cccc(C)c3)cc21 +Cc1n[nH]c(C(=O)NCCOc2ccc(F)cc2)c1Br +Cc1ccccc1C1(C(=O)N2CC(CO)OCC2C)CCCCC1 +COc1ccc2ncnc(NC3C(O)OC(CO)C(O)C3O)c2c1 +CNC(=O)c1c(C)nc(N)nc1-c1cccc(OCC(C)C)c1 +CC(C)Oc1cccc(C(=O)N(C)c2ncccc2F)n1 +O=C(CC1CCC1)N1CCc2ccc(Cl)cc2C1 +CC(C)CN1CCOC(CNC(=O)c2cc(Cl)cc(Cl)c2)C1 +CCSc1nnc(NC(=O)Cc2ccc(NC(C)=O)cc2)s1 +CCc1onc(C)c1NC(=O)NC(c1nc(C2CC2)no1)C(C)C +CCOc1ccccc1NS(=O)(=O)c1cnn(C)c1C +COc1cccc(NC(=O)c2cc(-c3csc(C)n3)c[nH]2)c1 +COc1ccc(-n2nnc(C(=O)Nc3ccccc3Cl)c2C)cc1 +CCC1c2ccc(C)n2CCN1C(=O)Nc1cc(OC)ccc1OC +Cn1cc(N2CCC3(CCN(C(=O)c4cccn4C)CC3)C2=O)cn1 +Cc1ccc(S(=O)(=O)NCCC(=O)N2CCCC2)cc1 +Cc1ccoc1C(=O)NC1CCN(c2ccc(F)cc2F)C1 +CC(=O)NCC(=O)NCC(=O)Nc1ccc2nc(C(C)C)sc2c1 +Cc1nc2sccn2c(=O)c1NC(=O)Cc1cccc(F)c1 +Clc1cnn(Cc2nc(-c3ccsc3)no2)c1 +Cc1ccccc1C1CC1C(=O)NCc1nnc2n1CCC2 +Cc1ccc(OCCOC(=O)c2n[nH]c(=O)c3ccccc23)cc1 +Cc1nnc(NC(=O)N2CCCCC2CCO)s1 +N#Cc1ccc2ncc(CNc3cnn(CC(F)F)c3)n2c1 +CC(C)(C)OC(=O)N1CCNC(c2ccccc2)C1 +COCCCn1c(-c2ccc(F)cc2)ccc(C(C)=O)c1=O +CCOC1CCN(C(=O)CCc2ccccc2)C1Cc1ccncc1 +CC(=O)NC(C)c1nc2ccccc2n1CC(C)C +NC(=O)C1CCN(C(=O)NCCc2cn3ccccc3n2)CC1 +CC(C)CNC(=O)N1CCCN(C(=O)c2ccncc2)CC1 +CC1CCCC(C)N1C(=O)CN1CCn2c(nnc2C2CC2)C1 +COc1cc(-c2scnc2N)cc(OC)c1OC +COc1ccc(N)cc1NC(=O)c1ccc(C)nc1 +CCOc1ccc(F)c(C(=O)N2CCSc3ccncc32)c1F +CCc1ccc(-n2ccc3c(nnc4nc(SC)nn43)c2=O)cc1 +CCC(=O)Nc1ccc(C)c(NCC(=O)Nc2ccccc2OC)c1 +O=C(CCC1CCN(C(=O)CC2CCCC2)CC1)NC1CC1 +CCCCn1c(SCC(=O)N(C)C)nnc1-c1ccncc1 +Cc1ccc(C)c(NC(=O)N2CCC(OCC(C)C)CC2)c1 +CC(=O)NC(CC(=O)Nc1nccs1)c1cccs1 +CN1CC2(CCN(C(=O)c3cc4sccc4[nH]3)C2)OC1=O +COC(=O)c1c(C)oc2cc(Br)c(O)cc12 +Cc1cc(C)cc(CCNC(=O)NC(CO)c2ccccc2)c1 +CCOc1ccc(-n2c3c(cc(C#N)c2=O)C(=O)CCC3)cc1 +CCCc1ccccc1NC(=O)c1cc(NC(C)=O)ccc1F +CCOc1ncccc1C(=O)N1CCN(C(C)=O)CC1 +C=C(C)CN(CC)C(=O)CSc1nc(-c2ccccc2)n[nH]1 +O=C(Nc1nncs1)c1cccc(-n2ccc(C(F)(F)F)n2)c1 +Cc1csc(S(=O)(=O)C(C)C(=O)Nc2ccccc2F)n1 +COc1ccc(OCCOc2c(C)[nH]ccc2=O)cc1 +CCc1nn(C)c(CC)c1CN1CC(C)OC(c2ccccc2)C1 +CN(c1ccccc1)S(=O)(=O)c1cc(F)cc(F)c1 +CCc1noc(C(C)NC(=O)c2cnc(-c3cccnc3)nc2)n1 +O=C(CCc1nc(C2CC2)no1)N1CCCC1c1noc(C2CC2)n1 +Cc1ncc(CNC(=O)Nc2ccc(OC(F)(F)F)cc2)s1 +COc1ccc(F)c(CN(Cc2sccc2C)CC(C)O)c1 +CC(Nc1ccc(C#N)cn1)C(=O)NCc1ccccc1 +CSc1c(F)cc(NC(=O)NCCO)cc1F +CNc1nccc(C2CCCCN2C(=O)c2cnco2)n1 +CC(CNC(=O)c1sccc1Br)N1CCOCC1C +Cc1ccsc1-c1nnc(CC(=O)NCc2ccccc2Cl)o1 +COc1cc(NC(=O)C2CCCC2)c(C(=O)N2CCCC2)cc1OC +CC(=O)Nc1ccc(CC(=O)NCCc2cn3ccccc3n2)cc1 +COc1ccc(NS(=O)(=O)c2ccc(C(C)=O)cc2)cc1 +N#CCc1ccnc(-c2cccc(Br)c2)n1 +Nc1cc(C(=O)NCCCCCO)ccc1Cl +O=C(CCNC(=O)c1ccco1)Nc1cccnc1-n1cccn1 +Cc1cccc(NC(=O)CN2C(=O)CCOc3ccccc32)n1 +COc1ccnc(NC(=O)c2cn(CCC(C)C)nn2)c1 +CN(CC(F)(F)F)C(=O)CN1CCOC(C)(C)C1 +Cc1cc2c(cc1N)CN(C)S(=O)(=O)C2(C)C +O=C(NCc1cn2ccsc2n1)C1CC1(Cl)Cl +COCCNC(=O)c1ccccc1NC(=O)CC1C=CCC1 +Cn1c(=O)n(Cc2noc(C3CC3)n2)c2ccccc21 +Cc1ccn2cc(C(=O)N3CCCC(NS(C)(=O)=O)C3)nc2c1 +COc1ccc(OC(C)C(=O)Nc2ccc3cn[nH]c3c2)cc1 +Cc1ccc2cccc(C(=O)NCc3c(C)c(C)n[nH]c3=O)c2n1 +CCOCC(=O)N1CCCN(C)c2ccc(Cl)cc21 +COCCN(Cc1ccsc1)C(=O)c1cc(C)cs1 +Cc1cc(N2CC(c3ccccn3)C2)n2nccc2n1 +CCOc1ccc(-c2nc(CC(=O)NC3CCCC3)no2)cc1 +CC(C)(C)c1nnc(CNc2c(F)cc(Br)cc2F)o1 +COc1cc(Cl)c(C)cc1NC(=O)c1ccc(F)c(N)c1 +CCCCS(=O)(=O)NC(C)c1cc(C)sc1C +N#Cc1ccccc1-n1nnc(-c2cccnc2)c1N +CCC(C)(NC(=O)c1cccc(NC(=O)NC(C)C)c1)C(=O)OC +O=C(NCC1CCCO1)C1c2ccccc2Oc2ccccc21 +Cc1ncc(C(=O)N(C)Cc2cccc(-n3cccn3)c2)s1 +CC(=O)Nc1cc(NCC(=O)Nc2cc(Cl)ccc2F)ccc1C +CC(=O)C(C)N1CC(C)Nc2cc(Br)ccc21 +CC(C)C(=O)NCc1cc(=O)n2c(n1)CN(S(C)(=O)=O)CCC2 +Cc1ccccc1CS(=O)(=O)c1nnc(NC(=O)C(C)C)s1 +COC(=O)CN(C(=O)c1scnc1C)C(C)C +Cc1c(N)cccc1NC(=O)CCSc1ncccn1 +N#Cc1ccc(OCCN2CCN(c3cnccn3)CC2)cc1 +CCOc1ccc(CC(=O)N=c2[nH]nc3cc(C)ccn23)cc1 +Cc1ccc(C(=O)OCC(=O)c2ccc3c(c2)NC(=O)CO3)c(C)c1 +COc1cccc(N(Cc2ccc(C)cc2)S(C)(=O)=O)c1 +O=C(Cc1cccc(O)c1)N1CCCc2ccccc21 +CC(C)(CNC(=O)c1cc(F)c(F)cc1F)c1ccncc1 +CCc1ccc(C(=O)CNC(=O)c2cccc(OC)c2)cc1 +COCc1nc(Cn2nc(C)c(C(C)C(=O)OC)c2C)cs1 +CCN1CCN(C(=O)C(C)(C)c2ccccc2)CC1 +C=CCN(Cc1ccccc1)S(=O)(=O)c1cccc(C(C)=O)c1 +Cc1ccc2ncc(C(=O)N(C)CC(F)F)n2c1 +CCc1ccccc1NC(=O)C1CN(C(=O)c2cnccn2)C1 +CC(C)N(C(=O)C(C(F)(F)F)C(F)(F)F)C(C)C +Cc1nn(C)c(C)c1NC(=O)C(C)N1CC(C)OC(C)C1 +NC(=O)c1c(NC(=O)Cc2cccs2)sc2c1CCCC2 +CCn1cc(C(C)NC(=O)c2ccc(Cl)cc2Cl)c(C)n1 +CCc1c(C#N)nnn1CCCOc1ccc(Cl)cc1 +C#Cc1cccc(N(Cc2ccco2)C(=O)CCc2ccnn2C)c1 +NC(=O)CCc1csc2nc(-c3ccc(Cl)cc3)cn12 +CNC(=O)c1ccc(CNS(=O)(=O)c2cc(F)cc(F)c2)cc1 +COc1cc(Br)cc(C)c1NC(=O)C1CCOC1 +COC(=O)c1cncc(C(=O)N2Cc3ccccc3OCC2C)c1 +COc1ccc2nc(Cc3nc(C)cs3)[nH]c(=O)c2c1 +CC(=O)N1CCC(Cn2ccc3cccnc32)CC1 +C=CCN(CC=C)C(=O)c1cc(-c2ccccn2)nc2ccccc12 +CCCNC(=O)n1ccc(C(=O)Nc2nccs2)n1 +COc1ccc(Br)cc1CC(=O)NCCCNC(C)=O +CC(Sc1nccn1C)C(=O)Nc1ccnn1C(C)C +CC(C)CC1COCCN1C(=O)CCn1cncn1 +COc1ccc(Oc2cc(CNC(=O)c3cc(C)n[nH]3)ccn2)cc1 +O=C(Cc1ccc(F)cc1)Nc1cc(F)cc(F)c1 +CCOc1cc(CNC(=O)c2noc(-c3cccc(F)c3)n2)ccn1 +COCCOc1ccccc1C(=O)NCC(=O)N(C)C +Cc1c(C(=O)C(C#N)c2ccccn2)oc2ccc(Cl)cc12 +CCOC(=O)c1sc2ncnc(NCc3cccnc3)c2c1C +CC(=O)NCCCC(=O)Nc1cc(C(N)=O)ccc1C +CCn1c(-c2ccccc2)cnc1SC(C)C(N)=O +O=C(CCc1ccco1)NCCC(=O)Nc1ccncc1 +CCOC(=O)c1cc(NC(=O)CCc2ccccn2)c[nH]1 +CCCC1CN(C(=O)Nc2ccc(Cl)c(NC(C)=O)c2)CCO1 +Nc1ccc2nc(CC(=O)NC3CCCC3)oc2c1 +COc1ccccc1OCCN(C)C(=O)c1cc(C)nn1C +Cc1noc(C)c1S(=O)(=O)Oc1ccc(F)cc1Cl +Cc1ccc(C(=O)NCCNC(=O)C2CC2)c(O)c1C +Cc1sc2ncn(Cc3cn4cc(Cl)ccc4n3)c(=O)c2c1C +CCc1nc2c(NC(=O)CC3CCCCC3)cccn2n1 +COc1ccccc1C1NCCc2c1ccc(F)c2O +CCCn1cc(-c2cc(-c3cccnc3)c(C#N)c(N)n2)c(C)n1 +CCC(CC)C(=O)NC(C#N)c1ccc(OC)cc1OC +Cc1ccc(NC(=O)NCC(O)COc2ccc(F)cc2)c(F)c1 +NS(=O)(=O)c1ccc(Br)c(Cl)c1Cl +CCC(NC(=O)c1ccc(C(=O)OC)cc1)c1ccc(C)cc1 +CCOCC1CCCN(C(=O)C2CC(=O)N(c3ccc(C)cc3)C2)C1 +CCN(CC(C)C#N)C(=O)c1cnc2ccc(C)cn12 +COC(=O)c1c(C)nn2c(-c3ccco3)ccnc12 +Nc1cccc(CCc2nc3ccc(N)cc3[nH]2)c1 +Cc1cccc(NS(=O)(=O)c2cccc(S(N)(=O)=O)c2)c1C +COc1ccccc1NC(=O)Cc1cn2c(nc1=O)SCC2 +CC1CCCCN1S(=O)(=O)NCCc1cccc2cccnc12 +COc1ccc(CCSc2nnc(C)c(=O)n2N)cc1OC +Cn1nc(C(=O)NCc2cccc(Cl)c2)c2ccccc2c1=O +CCC1CCc2ccccc2N1Cc1nnc(C2CCC2)n1C +O=S(=O)(NCc1ccccc1Br)c1cccs1 +Cc1cc(C(=O)NCC2(c3ccc(F)cc3)CC2)no1 +CCSc1cc(C(=O)Nc2cc(C)ccc2O)ccn1 +COc1ccc(F)cc1NC(=O)CN(C)C(=O)c1ccccc1 +O=C(Cc1ccccc1F)Nc1ccc2c(c1)COC2 +Cc1cccc(NC(=O)COC(=O)c2coc(-c3ccccc3)n2)c1 +COc1ccc2nc(SCC(=O)NC3CCOCC3)[nH]c2c1 +O=C(Nc1nnc(C2CC2)s1)c1cccc(OCC2CCCO2)c1 +O=C(NCc1cc(C2CC2)n(C2CCCC2)n1)C1CC1 +Cc1cccc2cnn(CCC(=O)NCCC(C)C)c12 +Cn1ccnc1C(NC(=O)c1n[nH]c2ccccc12)c1ccc(F)cc1 +Cc1c(C(=O)N(C)CCC(F)(F)F)nnn1-c1cccc(Cl)c1 +CC(C)(CO)CS(=O)(=O)N1CCCc2ccccc21 +CC(=O)c1ccc(NC(=O)c2ccc(S(=O)C(C)C)cc2)cc1 +Cc1nc(-c2cccnc2)[nH]c(=O)c1CCC(=O)N1CC2CCC1C2 +Cn1cc(C(=O)NC2CCN(c3ccc(Cl)cc3C#N)CC2)cn1 +CC(C)Cc1nnc(NC(=O)CCc2c[nH]c3ccccc23)s1 +Nc1c(S(=O)(=O)C2CC2)noc1C(=O)N1CCCC1 +CC(C)CC1(c2nc(-c3cnccn3)no2)CCC1 +Cc1csc2nc(CNc3ccc(C(F)(F)F)cc3)cc(=O)n12 +Cc1ccc(S(=O)(=O)Nc2cc(F)cc(F)c2)cc1 +CC(C)(C)n1cc(C(=O)OCC(F)(F)F)cn1 +Cc1n[nH]c(C2CCN(C(=O)CCc3ccc(C(C)C)cc3)CC2)n1 +Cc1cc(C(=O)Nc2nc3c(F)cccc3s2)nn1C +COc1ccc2nc(NC(=O)Nc3c(C)nn(C)c3OC)sc2c1 +COc1ccc(CNC(=O)C2CC=CC2)c(OC)c1 +CC1CN(C(=O)C2CCCN2C(=O)C2CC2)c2ccccc21 +Fc1ccc(COc2cccc(-n3cnnn3)c2)c2ncccc12 +CCC(C(=O)Nc1ccc(Cn2cncn2)cc1)n1nc(C)cc1C +O=S(=O)(NC1CC1)c1cnc(NC2CC2)c(Cl)c1 +CCn1nc(C)c(CN2CCCC(c3nnc4n3CCC4)C2)c1C +CCc1c(C(=O)NCc2cnc(C)s2)cnn1Cc1ccccc1 +CCc1ccsc1C(=O)NC(Cn1cncn1)c1ccccc1 +CCN(CC)C(=O)c1cnc(-c2ccc(Cl)cc2)nc1N +O=C1CN=C(c2ccccc2)c2cc(C(F)(F)F)ccc2N1 +Cc1nnc(NC(=O)c2occc2-c2ccccc2)s1 +CN(C)c1ncc(C(=O)NC(C)(C)CC(C)(C)C)c(N)n1 +O=C(c1cnc2ccccn2c1=O)N1CCN(c2ccccc2)C(=O)C1 +c1ccc(Cc2nn3c(-c4ccco4)nnc3s2)cc1 +COCCOc1nc(C2CCCO2)nc(NC(C)C)c1N +O=C(c1cccs1)N1CC(c2nc(-c3ccco3)no2)C1 +COC(=O)c1ccc(CNC(=O)COc2ccc3c(c2)CCC3)cc1 +Cc1cc(C)cc(CCC(=O)NC(C)c2n[nH]c(C)n2)c1 +Nc1cc(F)c(F)cc1NC(=O)c1ccc(F)cc1 +CC1CCN(C(=O)C2(C)Sc3ccccc3N(C)C2=O)CC1 +Cn1cnc(CNC(=O)C2(c3cccc(Cl)c3)CCCCC2)n1 +NC(=O)COc1ccccc1C(=O)OCc1nc2ccccc2s1 +Cc1cc(C(=O)Nc2nnc(-c3ccncc3)s2)cs1 +CCCS(=O)(=O)NCc1cccc(C(N)=O)c1 +CCOC(=O)c1ccc(NCc2nc3c(N)nc(N)nc3[nH]2)cc1 +CCn1c(Sc2ncnc3ccsc23)nnc1-c1ccoc1C +C#CCNC(=O)NCC(c1ccccc1)c1ccccc1 +N#Cc1cnn(-c2cc(-c3ccccc3)ncn2)c1N +Cc1noc(C(C)OC(=O)Cc2ccc(F)c(F)c2)n1 +Cn1cnnc1SCCNC(=O)CNC(=O)c1ccc(=O)[nH]c1 +Cc1ccc(-c2nc(CSc3nc(C4CC4)n[nH]3)cs2)o1 +CN(CC1CCCC1)C(=O)c1c[nH]c(=O)c(Cl)c1 +COc1ccc2[nH]cc(CCn3ccc(=O)c4c3CCCC4)c2c1 +Cn1nc(C#N)cc1-c1ccc(Cl)cc1Cl +CCOC(=O)c1ccc(N(C(C)=O)C(C)C(=O)N(C)C)cc1 +CC(C)(C)c1n[nH]cc1CNc1ccc2[nH]ncc2c1 +CC(=O)Nc1ccc(F)c(C(=O)OCC2CCCC2)c1 +Cc1nn(C)c(C)c1CC(C)NC(=O)NCC(C)Oc1ccccc1 +CCCC1CN(C(=O)c2cccc(-c3ccccn3)c2C)CCO1 +c1cnc(-n2cc(NCc3ccc4ccccc4c3)cn2)nc1 +CC(C)N(CCC#N)C(=O)c1cnc(-c2ccc3c(c2)OCO3)s1 +COCc1cccc(C(=O)Nc2nc(C3CC3)c(C(=O)OC)s2)c1 +CC(C)c1nnc(NC(=O)Cc2csc(-c3ccccn3)n2)s1 +Cc1noc(C)c1CN(C)C(=O)c1cc(C2CC2)nn1C(C)(C)C +CCC(C)n1ncc(C(=O)N2CC3CCCC3C2)c1C1CC1 +CC(=O)Nc1cccc(-c2nc(N(C)C)nc(C)c2C)c1 +CC(=O)N(Cc1cc2cccc(C)c2n2nnnc12)C1CCCC1 +CCOCCC(=O)Nc1cccc(C)c1C(=O)N1CCCC1 +O=C1CSc2ccc(NC(=O)c3cccs3)cc2N1 +N#Cc1cccnc1Oc1ccc(Oc2ccccn2)cc1 +COc1cc(CNC(=O)C2(C#N)CCCCC2)ccn1 +CN(C)S(=O)(=O)NCC(=O)Nc1cccc(F)c1 +CCOc1ccccc1N1CC(C(=O)NC2CCCC(C)C2)CC1=O +CC1(C)CC(C(=O)NCCSc2nc3ccccc3o2)CCO1 +CCS(=O)(=O)c1cccc(NC(=O)NC2C=CCCC2)c1 +Cc1cc(C)c(CNc2ncnc3ccsc23)c(=O)[nH]1 +Cc1ccsc1C(=O)NCc1ccc(Cl)cc1 +CCOC(=O)C1(N(C)Cc2cn(C)nc2C)CCCCC1 +Cn1nc(-c2ccccc2Cl)cc1C(=O)Nc1nccs1 +CCN(CC)C(=O)c1nc(-c2cccc3ccccc23)no1 +CCNC(=O)c1csc(COc2cccc(C)c2C)n1 +CN(C)c1cccc(C(=O)NC2CC(=O)N(C3CCCCCC3)C2)c1 +O=C(Cn1nnc2ccccc2c1=O)Nc1cccc(Cl)c1F +CCN1C(=O)C(C)(C)c2cc(S(=O)(=O)NCC(C)C)cc(C)c21 +CCN(CC)C(=O)Nc1cccc(OCC(=O)N(C)C)c1 +CCN1C(=O)CCc2cc(NC(=O)COC)ccc21 +Cc1ccc(Cn2nnc3cc(C(=O)Nc4cccnc4)ccc32)cc1 +CCOc1ccc(C(=O)NCc2ccccc2OC)cc1N +N#Cc1cccc(OCC(=O)Nc2sccc2C#N)c1 +CNS(=O)(=O)c1ccc(C(=O)Nc2ccnc(C)c2)cc1 +CN(Cc1cccc(F)c1)C(=O)COc1ccccc1C(N)=O +Cc1cccc(NC(=O)Nc2cnc(N3CCOCC3)nc2)c1C +CC(=O)c1ccc(C#N)cc1N1CCC(NC(=O)c2ccccc2)CC1 +CCOc1c(Cl)cc(C(=O)NC2CCC(=O)N(C)C2)cc1OC +CC(NC(=O)N(C)C(C)C)c1ccc(NC(=O)C2CC2)cc1 +O=C(NCc1ccco1)C1CCC(=O)N1Cc1ccco1 +Oc1ccc(CNCCc2cccc(F)c2)cc1F +Cc1ncnc(N2Cc3cnc(C(C)(C)C)nc3C2)c1C +CC(NC(c1ccc(F)cc1)C1CCC1)C(N)=O +COCC(C)(C)NC(=O)C1CC1c1ccccc1OC(F)(F)F +CCC(=O)Nc1cccc(NC(=O)CNc2c(C)cccc2CC)c1 +O=C(c1ccc(Br)cc1)C1CCCCN1 +O=C(COc1ccccc1)NCc1ccnc(OC2CCCC2)c1 +C=CCOc1cccc(NC(=O)NCc2ccnc(OC)c2)c1 +NC(=O)CN(Cc1ccccc1)S(=O)(=O)c1cccc(Cl)c1 +COc1ccc(-c2nc(-c3ccc(OC)c(N)c3)n[nH]2)cc1 +CCOC(=O)C1=C(C)Nc2nnnn2C1c1ccccc1OCC +CCN(CC)C(=O)c1cccc(NC(=O)c2cc(C)sc2C)c1 +Cc1ccccc1-n1ncc(C(=O)N2CCCC2c2cnn(C)c2)c1C +O=C(COC(=O)c1ccccc1)NC1CCCCC1 +Cc1n[nH]c(C(=O)Nc2ccccc2Cl)c1Br +CC1(NC(=O)NC2CCCCC2n2cccn2)Cc2ccccc2C1 +CC(=O)Nc1ccc(C(=O)CSc2nnnn2C(C)C)cc1 +Cc1ccc(-c2cccc(CN(C)Cc3nnc(C)n3C)c2)cc1 +Cn1cc(NC(=O)NC2CCc3c(O)cccc32)cn1 +CC(C)c1ccc(C2CCCN2C(=O)c2cnn(C)c2)cc1 +COCC(NC(C)=O)C(=O)NCc1ccccc1 +Cn1cc(C(=O)NCc2ccc(OC3CCCCC3)nc2)ccc1=O +COCc1ccccc1CNC(=O)c1ccc(O)c(Cl)c1 +COc1cccc(C(=O)Nc2cc3c(cc2N)CCCC3)c1 +CCOC(=O)CCC(=O)N1CCN(Cc2cnc3ccccn23)CC1 +Cc1ccc2c(c1)OC(C)CN2C(=O)c1cc[nH]c(=O)c1 +CCn1cc(CN(Cc2cccc(F)c2)CC2CCCO2)c(C)n1 +CC(=O)Nc1cccc(-c2nccn2Cc2cccc(C#N)c2)c1 +CCCC1CN(C(=O)c2cnc(-c3ccccc3)nc2C)CCO1 +COc1ccc(CN(C)CC(C#N)CCC#N)cc1F +COc1ccc(-c2n[nH]c(NC(=O)c3ccc(C#N)cc3)n2)c(OC)c1 +CS(=O)(=O)N1CCCCC1C(=O)N1CCCC(n2cncn2)C1 +Cc1ccc(Cn2cc(O)c(=O)cc2CN(C)CCO)cc1 +O=C(Nc1cc[nH]n1)c1ccc(Br)cn1 +O=C(NCCCO)Nc1ccccc1-c1ccccc1 +Cc1cccc(C(O)c2cc(F)cc3c2NC(=O)C3(C)C)c1 +COc1cccc(C(CNC(=O)c2cccc(Cl)c2)OC)c1 +Cc1cccc(NC(=O)CN(C)C(=O)CNC(=O)c2ccccc2)n1 +COC(=O)c1sc(NC(=O)c2cc3c(s2)CCCC3)nc1C +CC(C)c1cccc(C(C)C)c1NC(=O)CNS(C)(=O)=O +CNC(=O)C1CCCN1C(=O)Nc1ccc(C)c(Cl)c1 +O=C(COC(=O)c1cnccn1)NCc1ccc(Cl)cc1 +N#Cc1ccc(NC(=O)c2ccc(Cn3cncn3)cc2)cc1Cl +CC(=O)Nc1cccc(CNS(=O)(=O)c2cccs2)c1 +CC(C)c1ncc(Cl)c(C(=O)NC2(C)CCCC2)n1 +CCOc1ccc(N(C(CC)C(=O)NC)S(C)(=O)=O)cc1 +CC(C)C(C)NC(=O)N1CCC(OCc2ccc(F)cc2)CC1 +O=C(CSc1nncs1)NCCc1c(F)cccc1F +N#Cc1cc(-c2ccc(F)cc2F)cc2c1NCCC2 +COc1ccc(Cl)cc1C(=O)Nc1ccnc(C)c1 +CCCCN(C)C(=O)c1cc(-c2ccncc2)cn1C +NC(=O)C1CC(=O)N(c2ccc(Cl)cc2Cl)C1 +Cc1nc2ncc3c(=O)n(-c4cc(Cl)cc(Cl)c4)ccc3n2n1 +O=C(Nc1ccccc1N1CCOCC1)c1ccnc(F)c1 +Cc1ccc2c(c1)NC(C)C(=O)N2CC(=O)NCC(C)C +Cn1c2c(c(=O)n(C)c1=O)C(c1ccc(OCC#N)cc1)NC(=O)N2 +COc1ccc(S(=O)(=O)N2CC(C)OC(C)C2)c(C)c1 +O=C(NCc1csc(=O)[nH]1)c1cncc(F)c1 +Cc1cccc(C(=O)Nc2ccc(CC#N)cc2)c1 +O=C(C1COc2ccccc21)N1CCCC1c1noc(C2CC2)n1 +Cc1cc(Cl)ccc1OCC(=O)NCC(O)c1ccco1 +CSc1nc2n(n1)C(CC(=O)Nc1ccccc1)C(=O)N2 +Cc1ccc(NS(=O)(=O)c2c(C)nn(C)c2C)cc1F +NS(=O)(=O)c1ccc(NC(=O)C23CCC(CC2)C3)cc1 +Cc1ccccc1-c1cccc(C2NC(=O)c3n[nH]c(C)c3N2)c1 +Cc1ccc(=O)n(CC(=O)Nc2ccccc2Nc2ccccc2)n1 +COCC(C)N(C)C(=O)Cn1nnn(-c2cccs2)c1=O +COC(=O)c1cccc(NC(=O)NCc2ccc(F)cc2)c1 +CS(=O)(=O)N1CCc2nc(NC(=O)c3ccco3)sc2C1 +CC(CC(O)=Nc1ccc(F)cc1F)n1ccnc1 +COc1cccc2c(=O)c(C(=O)NCc3ccncc3)c[nH]c12 +O=C(NCc1coc(-c2cccs2)n1)c1ccc(Cl)cc1 +COC(=O)Cn1c(C)cc(=O)c2cc(F)cc(F)c21 +CCNC(=O)c1cc2c(C)nn(C(C)(C)C)c2nc1N +COC(=O)C1CCn2nc(Cc3ccccc3)nc2C1 +CCCC1CCC(NC(=O)c2ccc(CNC(C)=O)cc2)CC1 +CC(CN1CCCC1=O)Nc1ccc(S(=O)(=O)C(F)F)cc1 +CC(C)c1nn2c(C#N)c(-c3ccccn3)nc2s1 +O=C1CN(Cc2cnc(C3CCC3)s2)C2CCCCC2N1 +CCOCCSc1nc2ccccc2c2nc(C)nn12 +O=C(NCc1ccco1)c1cn2ccnc(-c3ccc(F)cc3)c2n1 +CC1CCCN(S(=O)(=O)c2ccc(C(=O)C(C)C)cc2)C1 +O=C(CC1CCCC1)NCCn1ccc(-c2ccccn2)n1 +COc1cc(CO)cc(Br)c1OCCOC(C)C +O=C(Nc1cccc(Cl)c1)C1CC(=O)N(C2CC2)C1 +Cc1nnc(NCCCN2CCCCCC2=O)c(C#N)c1C +CNC(=O)c1ccc(OC)c(NCC(=O)NCc2ccccc2C)c1 +COc1cccc2c1OCC(NC(=O)c1ccoc1C)C2 +Cc1ccc(S(=O)(=O)NCCNC(=O)C2CC2)cc1 +CC(=O)Nc1cccc(OC(=O)C2CC2c2ccccc2)c1 +Cc1ccc(CNC(=O)CNC(=O)c2ccc(F)cc2F)n1C +CC(C)(C)n1cnc2cc(NS(=O)(=O)c3ccccc3)ccc21 +Cc1ccc(C)c(S(=O)(=O)NCC(O)c2ccc3c(c2)CCO3)c1 +N#Cc1cccc(SCc2cc(=O)c(O)co2)c1 +COc1ccc(OC)c(C(=O)c2cnc3ccccc3c2)c1 +O=C(Nc1nccs1)c1cnc2sccn2c1=O +Cc1ocnc1C(=O)NCc1cc2n(n1)CCCN(C(=O)N(C)C)C2 +O=C(Cc1ccc(NCc2ccco2)cc1)NCc1ccc(F)cc1 +COc1ccc(OC)c(COC(=O)C(C)c2cccs2)c1 +CCCC(=O)Nc1ccc(CC(=O)NCc2nnc(C)o2)cc1 +CCc1ccccc1CNC(=O)C1(C#N)CCCC1 +CCOC(=O)C(C)C(O)(c1ccccc1)c1ccccc1 +COc1ccc2c(ccn2CC(=O)N2CCCC2Cn2cccn2)c1 +COc1cccc2c1CCC2NCc1cnc(C2CCC2)s1 +Cc1ccc(Cl)cc1NC(=O)NCCCOCC1CCOC1 +N#Cc1cccnc1NCCC(=O)NCc1ccccn1 +COC(=O)C(NC(=O)OCc1ccccc1)OC +CC(=O)N(C)Cc1cccc(NC(=O)N(C)Cc2ccccn2)c1 +O=C1Cc2cc(S(=O)(=O)N3CCc4ccccc43)ccc2N1 +Cc1ccc(NCC(=O)N(C)CC(=O)NC2CC2)cc1 +CCc1nc(CNc2ccc(Br)cc2C(=O)NC)n[nH]1 +CCOC(=O)CN(CC)C(=O)c1ccc2c(c1)OCCO2 +COc1ccccc1NC(=O)c1c(O)cc(F)cc1F +Cc1csc(C2CCCCN2C(=O)CCn2nc(C)cc2C)n1 +Cc1ccc2nc(Cn3cnc4sccc4c3=O)cc(=O)n2c1 +COC(=O)c1sccc1NC(=O)Cc1c(F)cccc1F +Cc1ccc2cc(C#N)c(SCC(=O)NC3CCCC3)nc2c1 +CCCOc1c(Cl)cc(CN2CCOC(C(N)=O)C2)cc1OC +Cc1cc(C)c(NC(=O)CCC2CCCC2)c(C)n1 +C=CCN1CCN(C(=O)c2ccccc2F)c2cccnc21 +CC(C)Oc1ccc(-c2cn(-c3cccc(N)c3)nn2)cc1 +Cn1cc(CCNC(=O)N2CCCCCC2)cn1 +CCS(=O)(=O)N1CCn2c(COc3ccccn3)nnc2C1 +O=C(Nc1cccc(NC(=O)c2ccc[nH]c2=O)c1)c1ccco1 +Cc1noc(C23COCC2CN(C(=O)c2ccncn2)C3)n1 +O=C(NCc1ccc(Br)cc1Cl)c1ccoc1 +CN(C(=O)CC#N)c1cccc(Br)c1 +COc1cc(CNC(=O)c2nnn(-c3ccc(C)cc3)c2C)ccn1 +Nc1ccc(SCc2csc(-c3ccco3)n2)cn1 +CC(CO)(CO)NC(=O)CCc1ccc2ccccc2c1 +c1csc(CN2CCc3n[nH]c(-c4ccc5c(c4)OCO5)c3C2)c1 +COC(=O)CNC(=O)C1(c2ccc(F)cc2F)CCOCC1 +Cc1ccc(OC(=O)C2CCCN2S(=O)(=O)c2ccccc2)cc1 +CC(C)(C)OC(=O)N1CCC(c2nc(-c3cccs3)n[nH]2)CC1 +O=C(CCSc1ccccc1)NCC(F)(F)F +CN(CCc1ccccn1)c1ccc(C(F)(F)F)cc1N +c1ccc(-n2cc(-c3nn4c(-c5ccncc5)nnc4s3)cn2)cc1 +COC(=O)C1CCN(C(=O)NC(CCCO)c2ccccc2)CC1 +COC(=O)N=c1n(C)c2ccccc2n1CC(=O)c1ccccc1 +CCNC(=O)NC(CC(=O)OCC)c1ccc(F)cc1 +C=CCN(Cc1ccc(OC)cc1)C(=O)NC(C)c1ccncc1 +COc1cccc(OCC(=O)NCc2ncc(-c3ccccc3)o2)c1 +CC(C)CC(=O)NC(C(=O)N1CCC(C(N)=O)C1)C(C)C +COC(=O)CCN(C)C(=O)c1c[nH]c2ccccc12 +COC(CNS(=O)(=O)c1ccc(F)c(F)c1)c1cccc(F)c1 +CC(CN1CCCC1=O)NC(=O)c1ccccc1O +CC(C)(C)c1nnc(CNc2ccc(C(=O)NC3CC3)cc2)o1 +CCc1nnc(NC(=O)CCc2ccc3c(c2)OCO3)s1 +CCN(Cc1ccccc1C#N)C(=O)c1sccc1C +Cc1nc(CNC(=O)c2cc(C)n(-c3nccs3)c2C)c(C)s1 +O=C(OCC(=O)N1CCOCC1)c1csc(-c2cccs2)n1 +O=C(CCSc1cccc2cccnc12)N1CCCCCC1 +Cc1ccccc1C(=O)Nc1cc(C#N)c2[nH]c3ccccc3n2c1=O +O=C(NCCCN1CCCC1=O)c1cccc(C(F)(F)F)c1 +O=C(Cn1cnnn1)Nc1cnc2ccccc2c1 +COC1CCN(Cc2ccc3c(c2)OCO3)C1Cc1cnn(C)c1 +CS(=O)(=O)c1ccc(F)c(NCCOc2ccc(C#N)cc2)c1 +CC(C)(C)c1csc(-c2ccc(-n3cncn3)nc2)n1 +CC1Nn2c(nnc2-c2cccc(Cl)c2)SC1C +CC1CC1NS(=O)(=O)c1ccc(F)cc1C#CCO +Cc1noc2nc(-c3cccs3)cc(C(=O)OCC3(C)COC3)c12 +COc1cc(-c2ncc(C(C)=O)s2)cc(OC)c1OC +CC(CNC(=O)Cn1cnnn1)c1c(Cl)cccc1Cl +Cc1cccn2c(=O)cc(OCC(=O)c3ccccc3)nc12 +CC(CN(C)C(=O)c1cc(F)cc2[nH]cnc12)c1nccs1 +CC(O)c1c(-c2ccncc2)nc2ccc(Cl)cn12 +Cc1nnc(NC(=O)CCn2cnc3ccccc3c2=O)s1 +O=S(=O)(Cc1ccccc1)N1CCN(S(=O)(=O)C2CC2)CC1 +Cc1ncsc1C(=O)N(C)Cc1cc(N)ccc1Cl +CCCCc1nc2cc3c(cc2n1CCC#N)OCO3 +Cc1cc(C(=O)COc2ccccc2F)c(C)n1C1CC1 +Cn1cc(C(=O)Nc2cccc(Cl)c2)c(=O)c2cc(Cl)ccc21 +CC1CC(C)CN(C(=O)C2CC(=O)N(C3CCCC3)C2)C1 +Cc1cc(C)n2nc(SCC(=O)c3ccc4c(c3)OCO4)nc2n1 +Nc1ccnc(COc2cccc(Cl)c2Cl)n1 +Cc1nc(C2CCCN2C(=O)c2csc3c2CCCC3)no1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1cc(C)n(C(C)C)c1C +COc1ccc(C#CCNC(=O)COc2cccnc2)cc1 +COC(=O)c1cccc(CSc2nc(C)c(C)c(=O)n2C)c1 +CC(=O)c1cccc(OS(=O)(=O)c2ccccc2C#N)c1 +Cc1c(-c2ccnn2C(=O)c2ccco2)cnn1-c1ccccc1 +N#Cc1cccc(OCCN2C(=O)c3ccccc3CS2(=O)=O)c1 +COc1ccc(C)c2c1N(C(=O)c1cnc(C)s1)CCC2 +COC(=O)Cn1nc(-c2c(F)cccc2Cl)c2c1CCNC2 +O=c1[nH]c2ccccc2cc1CNc1ccc(Cl)cc1 +NC(C(=O)NCCO)c1ccc(Cl)c(Cl)c1 +Cc1nc2ccccn2c1C(=O)N(CCc1cccs1)C1CC1 +O=C(c1ccncn1)N1CC2CCCC2(COCc2cccnc2)C1 +Cc1nc2cc(NC(=O)Cn3c(=O)cnc4ccccc43)ccc2o1 +CCN(CCC#N)C(=O)CCc1ccc(OC)cc1 +N#Cc1ccc(OC(=O)CCCOc2ccccc2)cc1 +Cc1nc(N(C)CCO)c2nnn(Cc3ccccc3)c2n1 +Cc1ccc(C(=O)N2CCc3ccc(N)cc32)s1 +CCOc1ccccc1NC(=O)COc1nnc2ccccn12 +COC(CNC(=O)c1c(C)nn2cccnc12)c1cccc(Cl)c1 +O=C(Nc1cc(-n2ccnc2)ncn1)c1cnn(-c2ccccc2)n1 +O=S(=O)(Nc1ccc(Oc2ncccn2)cc1)c1ccccc1F +COc1ccccc1-c1nc(C(=O)N(C)C(C)CC#N)cs1 +CCOc1ncccc1C(=O)NCc1cc(Cl)c2c(c1)OCCO2 +C=CCNC(=O)N1CCc2nc(NC(C)=O)sc2C1 +CCC(NCc1cc(Cl)ccc1C)C(=O)OC +CC(OC(=O)c1ccn2cncc2c1)c1nc2ccccc2o1 +CNC(=O)Cn1ccc(-c2cccc(-c3ccccc3SC)c2)n1 +N#Cc1ccc(NC(=O)Cc2csc(-c3ccccn3)n2)cc1 +Fc1cnc(OCC2OCCc3cn(CC4CC4)nc32)nc1 +CC(CCCO)NC(=O)N(C)C(C)c1ccncc1 +CS(=O)(=O)N1CCCC1c1ccccc1Cl +CCN(CC)c1nccc2c(N)cc(Br)cc12 +COc1cc(F)ccc1NC1CCN(C(N)=O)CC1 +OCC(O)Cn1cc(-c2cccc(-c3ccco3)c2)nn1 +CC(C)C(NC(=O)c1ccc(Cl)cc1)C(=O)N(C)CCC#N +O=C(Cn1ccc2ccccc21)NCc1cccs1 +C#CCN1CCN(C(=O)NC2COc3ccc(C)cc32)CC1 +CC(C)(C)CCC(=O)Nc1cc(F)ccc1NC(=O)c1ccccn1 +CNC(=O)c1cc(S(=O)(=O)NCc2ccco2)ccc1C +Cc1cc(F)ccc1CCNC(=O)NCc1cc(C(C)C)no1 +Cc1noc(C)c1S(=O)(=O)N(C)CCOc1ccccc1Cl +CCCOCC(=O)N1CCOC(c2cccc(OC(F)F)c2)C1 +CCN(CC(C)C#N)C(=O)CNc1cc(Cl)ccc1C(N)=O +CCSc1ccc(-c2cc(CO)c(COC)o2)cc1 +Cc1cc(=O)sc2c1c(C)nn2-c1ccccc1 +CCC(=O)Nc1ccc(CSc2nc(C)n[nH]2)cc1 +Cc1ccc2cc(C(=O)N3CCOC(C)(C)C3)[nH]c2c1 +O=C(Nc1cc(N2CCOC2=O)ccc1F)NC1CC1 +CCCC(=O)N1CCC(C(=O)Nc2cccc(Cl)c2OC)CC1 +CCc1nnc2n1CCN(C(=O)C1(c3ccccc3)CC1)C2 +CCn1cc(C(=O)Nc2ccc(C)c(Br)c2)cn1 +CC(NC(=O)C(C)(N)c1ccccc1)c1ccco1 +CC(C)CN1C(=O)C(CC(=O)NC(C)(C)C)Sc2ncccc21 +COCC(=O)NCCNS(=O)(=O)c1cccc2nonc12 +Cc1cc(C)c2c(-c3ccc(F)cc3)c(C#N)c(=O)n(C)c2n1 +CC1CCC(Oc2cc(CNC(=O)NCCO)ccn2)CC1 +Nc1ccc2c(c1)c1ccccc1c(=O)n2CCO +CN(C)c1ncnc2c1CCN(C(=O)C(O)c1ccc(Cl)cc1)C2 +Cc1ccc(OCC(=O)c2ccc3c(c2)OCO3)c(N)c1 +COC(=O)C(Cc1ccccc1)NC(=O)c1cnn(C)c1 +COc1ccc(NC(=O)NCc2cn3cc(Cl)ccc3n2)cc1 +COCCNC(=O)C1COC(=O)N1CC1CCCCC1 +O=C(Nc1nonc1-c1nc2ccccc2[nH]1)c1ccc(F)cc1 +Cc1ccc(OCCCOc2c(C)[nH]ccc2=O)cc1 +COc1ccccc1-c1cc(C(=O)N=c2[nH]cc[nH]2)[nH]n1 +O=C(Nc1ccc2nccnc2c1)c1ccc(F)cc1F +CC(=O)Nc1cccc(OCCNC(=O)NC(C)c2ccccn2)c1 +CCCS(=O)(=O)NC1CCN(C(=O)COCC)CC1 +CCC(=O)N1CCC(c2nc(-c3ccccn3)no2)C1 +COC(=O)CC(NC(=O)c1ccc(Cl)cc1Cl)C1CC1 +O=C1NCCN(C(=O)COc2ccccc2)C1c1ccccc1 +Fc1ccc2c(c1F)C(C=Cc1ccncc1)NCC2 +CCCCCNC(=O)c1onc(-c2ccc(C)cc2)c1N +Cc1ccc(-c2nc(-c3ccc4c(c3)[nH]c(=O)c(=O)n4C)no2)cc1C +CC(C)CN1CCOC(CNC(=O)c2ccc(Cl)cc2F)C1 +CC(C)(C)c1ccc2c(c1)C(c1cc[nH]c(=O)c1)NCC2 +Cc1ccc(NC(=O)Nc2ccc3nncn3c2)cc1F +CC1c2cccn2CCN1C(=O)c1ccc2ncsc2c1 +COCCCNS(=O)(=O)c1c(C)cc(C)cc1C +CN(C)S(=O)(=O)c1ccc2nc(NC(=O)C(C)(C)C)sc2c1 +CCC(Cn1nc(-c2ccc(OC)cc2)ccc1=O)NC(=O)C(C)C +Cc1sc(=O)n(CC(=O)Nc2cccc(N3CCOC3=O)c2)c1C +Cc1[nH]cc(C(=O)N(C)CCOCC2CC2)c(=O)c1Br +Cc1cc(C(N)C(=O)NCc2ccc[nH]2)ccc1O +CC(Sc1ccccc1S(C)(=O)=O)C(=O)c1ccccc1 +Cc1cn2cc(C(=O)NC(Cn3cccn3)c3ccccc3)ccc2n1 +O=C(C1CCCCO1)N1CCc2ccc(O)cc2C1 +CC(=O)Nc1ccc(CNC(=O)c2ccc(C)nc2)cc1 +COc1ccc(-c2n[nH]c(SCc3cccnc3)n2)c(OC)c1 +Cc1ccccc1-n1cnnc1SCc1n[nH]c(=O)[nH]1 +O=C(Nc1ccc(S(=O)(=O)N2CCCC2)cc1)c1ccccn1 +COc1ccc(Br)c(CNc2ccc3nnnn3n2)c1 +CC(=O)N1CCN(CC(O)COc2ccc(Cl)cc2)CC1 +COc1ccc(CCOc2cccc(CO)c2)cc1 +Cc1noc(C2CCCN(C(=O)CCC3CCCCC3)C2)n1 +CN(Cc1cccc2cnccc12)c1nncc(-c2ccc(F)cc2)n1 +COC(=O)Nc1cccc(OS(=O)(=O)N(C)C)c1 +Cc1ccc2cccc(NC(=O)c3ccc4c(c3)OCCO4)c2n1 +O=C(c1ccoc1)N1CCCC1c1cccc(F)c1 +C=CCN(CC=C)C(=O)c1ccc2c(c1)nnn2CC +Cc1cccc(C)c1NC(=O)c1cccc(-c2ccoc2)c1 +Cn1c(=O)c2cc(NC(=O)c3ccccc3F)cnc2n(C)c1=O +Cn1c(=O)n(CCC(=O)NCC2CCOC2)c2ccccc21 +CS(=O)(=O)c1ccc(NC(=O)C2CCC2)cc1 +Nc1cc(N2CCCCC2)nn1-c1cccc(Cl)c1 +CCc1ccc(C(c2c(O)n[nH]c2C)C(C#N)C#N)cc1 +Cc1cccc2c(N3CCCC(N4CCNC4=O)C3)c(C#N)cnc12 +Cc1ccc(CNCC(O)c2ccccc2)cc1F +O=C(Cc1ccc(N2CCCC2=O)cc1)NCC1(c2ccccc2)CC1 +CC(C)(C)c1nc(CS(=O)(=O)c2ccc(F)c(F)c2)no1 +CC(NC(=O)c1snc(-c2ccccn2)c1N)c1ccncc1 +CCOc1cc(NS(=O)(=O)c2cc(C)ccc2F)ccc1OC +CCS(=O)(=O)NCCCCN1CC(C)OC(C)C1 +CCOc1ccccc1C1(C)Nc2ccccc2C(=O)N1CC +Nc1ccc(O)c(C(=O)OCC2CCOCC2)c1 +Nc1ccc(C(=O)NCC23CC4CC(CC(C4)C2)C3)cn1 +O=C(NC1CCCc2cn[nH]c21)C1(Cc2ccccc2)CCC1 +Cc1nc2ccc(NC(=O)C3CCN(C(N)=O)CC3)cc2s1 +CCOC(=O)c1cc(NC(=O)Nc2ccccc2Cl)c(C)nc1C +Cn1cc(C(=O)NCCSc2ccccc2)ccc1=O +Fc1ccc(-c2noc(CN3CCCC4(C3)OCCO4)n2)cc1F +CCn1c(CN(C)c2ccnc3ccncc23)nc2ccccc21 +CCC(=O)Nc1ccc(NC(=O)CNc2ccccc2OC)cc1 +CCn1c(C)cc(C(=O)NCC(C(C)C)N2CCOCC2)c1C +CC(=O)N1CCC2CN(CC(C)C)S(=O)(=O)C2CC1 +CCc1nnnn1Cc1nnc(-c2cccs2)o1 +CCOc1cccc(C(C)NC(=O)NCC2CC2)c1 +C=CCNc1ncnc(Nc2ccc(C)c(C)c2)c1N +CCC(c1ccncc1)N(C)C(=O)Nc1cc(C)cc(C)n1 +c1ccc(N2CCN(Cc3ccc(-n4ccnc4)nc3)CC2)cc1 +COc1ccc(OC)c(C(C)NC(=O)c2cccnc2SC)c1 +O=C(COc1cccc(CNC(=O)C2CCCCCC2)c1)NC1CC1 +C#Cc1cccc(NC(=O)c2cc(Cl)ccc2-n2cnnn2)c1 +O=C(OCCNc1ncccn1)C1COc2ccccc21 +Cc1ccc(NC(=O)COc2ccc[nH]c2=O)cc1 +Cc1occc1C(=O)N1CCc2cc(Br)ccc21 +CC(C)c1csc(NC(=O)Cn2cnc3ccccc3c2=O)n1 +Nc1ccccc1S(=O)CCOCC(F)(F)F +COc1ccccc1OCC(=O)NC1CCCC(C)C1C +Cc1sc2ncnc(NCCS(=O)(=O)c3ccccc3)c2c1C +Cn1ccc(NC(=O)Nc2cccc(C(=O)NCc3ccccc3)c2)n1 +O=S(=O)(c1ccc(CNCc2cscn2)cc1)N1CCCC1 +CCN(C(=O)c1cn2c(C)cccc2n1)c1ccccc1C +COCCOc1ccc(NC(=O)C2CC=CC2)cn1 +CCc1nc(C)c(C(C)N(C)C(=O)NCc2ccco2)s1 +Cc1cc2c(nc1C)sc1c(NCCCO)ncnc12 +COc1ccccc1CN(C)C(=O)c1cc(Cl)c2c(c1)OCCO2 +CCN(CC)S(=O)(=O)c1cc(-c2ccno2)oc1C +Cc1nc(-c2cccc(C(=O)Nc3ccc(F)c(F)c3)c2)no1 +CCCn1c(C)nnc1SC(C(=O)NC1CC1)c1ccc(F)cc1 +CC1CN(C(=O)c2cc3sccc3n2C)CC(C)O1 +COc1ccc(C(=O)CCC(=O)N2CCCC2)cc1C(C)C +Cc1nc(C)c(C(=O)NCc2cccnc2OC2CCCC2)s1 +N#CC(NC1CCCCC1)c1ccc2c(c1)CCO2 +C#CCN1CCN(C(=O)CNc2ccc(F)c(NC(=O)OC)c2)CC1 +O=C(COc1ccccc1)NCC1Cc2cccc(F)c2O1 +CCCCCC(=O)NC1CC(=O)N(c2ccccc2)C1 +COC(=O)CCNC(=O)CNC(=O)c1cccc(Cl)c1 +CCCn1nc(C)c(CN2CCC3(C2)OCCO3)c1C +CCOCCCNC(=O)c1csc(-c2ncccn2)n1 +Cc1ccc(C(=O)n2nnc3ccccc32)c(F)c1F +CN(CC1CC1)C(=O)COc1cc(Cl)cc(Cl)c1 +COc1cc(CNC(=O)N(C)Cc2ccc(Cl)cc2)ccn1 +Cc1ccc(NC(=O)N(C)Cc2cnn(C)c2)cc1Cl +Cc1csc(NC(=O)CN2CCc3cncnc3C2)n1 +CC(C)(C)OC(=O)N1CCCCC1C(=O)Nc1ccccn1 +CC(C)(C)N(CC(=O)Nc1ccc(F)cc1)C(=O)C1CCOC1 +Cc1nn(C)c(C)c1CN(C(=O)c1cc2ncccn2n1)C1CC1 +COc1ccc(Cn2c(-c3ccc(O)c(OC)c3)n[nH]c2=O)cc1 +OCCC1CN(Cc2cc[nH]n2)CCN1Cc1ccc(F)cc1 +Cc1cc(C)n(C2CCCN(C(=O)COc3cc(F)ccc3F)C2)n1 +CCC(C)NC(=O)Cn1c(Nc2ccc(F)c(C)c2)nc(C)cc1=O +CC(C)OC(C)c1n[nH]c(=O)n1CC1CCCCC1 +COCCN1CCN(C(=O)NC(C)C(C)(C)C)CC1=O +CCCC(=O)NCC1CCN(C(=O)Nc2ccccc2OC)CC1 +CN(C)C(=O)CCNC(=O)c1c(F)cc(Br)cc1F +COCCOC(=O)CN1C(=O)COc2ccc(C(C)=O)cc21 +COc1cc(C#N)ccc1OCc1nc(-c2ccc(C#N)cn2)no1 +COCC(=O)N1CCCN(Cc2cnc(-c3ccccn3)nc2)CC1 +Cc1cc(NC(=O)c2nnn(-c3ccccc3)c2C)no1 +Cc1sc2c(=O)n(C3CC3)cnc2c1C(=O)Nc1ccccc1F +CCOc1ccccc1NC(=O)CNc1cccc(C(=O)NC)c1 +Cc1ccccc1C(=O)NC(C)c1cccc(S(N)(=O)=O)c1 +CCNC(=O)c1cccnc1N1CCN(c2cccc(Cl)c2)CC1 +CC(C(=O)Nc1ccccc1Cc1ccccc1)N1CCOCC1 +O=C(NCCc1n[nH]c(C2CCCCC2)n1)c1cccc(Cl)c1 +Cc1cc(C(=O)NCc2ccn(-c3ccc(F)cc3)n2)on1 +CCn1ccnc1N1CCN(C(=O)CC(C)C)CC1 +Cc1cc(C)nc(N(Cc2ccccc2)C2CC2)n1 +CN(CC(=O)NC1CC1)C(=O)CSc1ccccc1O +CC(C)OCc1c(C(=O)NCc2cnn(C)c2)oc2ccccc12 +COc1ccc2cc(CNC(=O)COc3ccccc3O)ccc2c1 +CC(=O)N(CCc1ccccc1)Cc1nc(-c2ccncc2)no1 +Cc1cc(C)n(CCOC(=O)c2ccc(N3CCC(C)CC3)nc2)n1 +Cc1cc(SCC(=O)N2CCNC(=O)C2)nc2ccccc12 +O=C1CN(C(=O)Cc2ccc(S(=O)(=O)C(F)F)cc2)CCN1 +O=S(=O)(Nc1ccncc1)c1cccc(C(F)(F)F)c1 +O=C(NCC#Cc1ccc(F)cc1)C1(c2ccccc2)CCOCC1 +CC(=O)Nc1cc(Cl)ccc1NC(=O)c1ccc(F)nc1 +CN(CCOc1ccc(F)cc1)C(=O)c1n[nH]c(=O)c2ccccc12 +Cc1noc(NC(=O)COc2ccc(Cl)c(Cl)c2)n1 +O=c1c(Cl)cc(C(F)(F)F)cn1Cc1noc(-c2ccoc2)n1 +COc1cc2ncn(CC(=O)Nc3nccs3)c(=O)c2cc1OC +O=C(CCC1CCCC1)OCC(=O)c1c[nH]c2ccccc12 +COC(=O)c1cccc(C(=O)Nc2c(C)cc(C)nc2C)c1 +O=C(Nc1nncs1)c1csc2c1CCCC2 +O=C(c1ccccc1)N1CCn2c(nnc2-c2cccs2)C1 +Cc1c(Cl)cccc1NC(=O)c1ccc2c(c1)NC(=O)CS2 +Cn1c(=O)[nH]c(=O)c2c1nc1oc(C(C)(C)C)cn12 +COCCN1CC(C2=NC(C(=O)OC)C(C)=N2)CC1=O +COc1ccc(CN2C(=O)C(=O)c3ccccc32)cc1 +C=C(c1ccccc1)C1NCCc2c(OC)cc(O)cc21 +NC(=O)COc1ccc(NC(=O)c2cc(=O)[nH]c3ccccc23)cc1 +CC(C)Cc1ccc(C(=O)N2CCC(=O)CC2)cc1 +CC(C)(C)OC(=O)NCC1CCCN1C(=O)c1cnccn1 +COc1ccc(NC(=O)Cn2ccc(N)n2)cc1Cl +CCCOc1ccccc1-c1cnn(CC)c(=O)c1C(C)=O +CC(C)=CC(=O)OCC(=O)NC(C)(C#N)C(C)C +O=C(CSc1ccc(O)cc1)Nc1c(F)cccc1NC1CC1 +Cc1nc(CCCC(=O)NCC2CN3CCCCC3CO2)cs1 +COc1ccc(NC(=O)N2CCC(C)CC2)cc1F +C#Cc1cccc(NCc2cc(=O)n3cccc(C)c3n2)c1 +Cc1cccc(CNc2cc(C(N)=O)ccc2C)c1 +CC(=O)N(Cc1cc2ccccc2[nH]c1=O)c1ccc(C)c(C)c1 +O=C(c1cc[nH]n1)N1CCN(c2ccc(O)cc2)CC1 +Cc1cc(N)ccc1NC(=O)C(C)Oc1ccc(F)cc1 +CCc1ncc(NC(=O)N2CCN(Cc3nc(C)c(C)o3)CC2)cn1 +O=C(OCCNC(=O)c1ccc2ccccc2n1)c1ccccc1 +Cc1cc2nnc(SC(C(N)=O)c3ccc(F)cc3)n2c(C)n1 +CS(=O)(=O)NC1CCN(c2ccc3nnnn3n2)CC1 +O=C(Nc1nnc(-c2ccno2)o1)c1ccc(Cl)cc1Cl +Cc1n[nH]c2ncc(C(=O)N3CCOCC3C3CC3)cc12 +Cc1cccc(C(C(=O)NCCN2CCCC2=O)N(C)C)c1 +Cn1nnnc1SCCCc1ccc(Cl)cc1 +O=C(Nc1cc(-c2ccccc2)n[nH]1)c1n[nH]cc1Cl +CCC(C)N(C)C(=O)Nc1cnc2c(c1)c(C)nn2C +CN(C)c1ncccc1C(=O)Nc1cnc2ccccc2c1 +Cc1cccc2cnn(CCC(=O)Nc3cccc(C(N)=O)c3)c12 +COC(=O)c1ccc(Cn2cnc3c(N)ncnc32)cc1 +CN(C(=O)CS(=O)(=O)c1ccccc1F)C1CC1 +Cc1cc(O)ccc1NC(=O)N=c1[nH]nc2ccccn12 +CC(=O)N(C)CC(=O)N1CCN(CC(=O)NC2CC2)CC1 +CN(CCO)C(=O)c1cccc(Oc2nccc(C(F)(F)F)n2)c1 +Cn1ccnc1-c1nnc2sc3ccccc3n12 +O=C(Cc1nc(CO)cs1)Nc1cc(Cl)ccc1Cl +Nc1c(-c2cc(Cl)ccc2O)nc2c(F)cccn12 +CC(Cc1cccs1)NC(=O)c1ccnc2ccccc12 +CN1CC(NC(=O)NCC(C)(O)c2ccsc2)CCC1=O +Cc1cc(C(=O)N2CCN(CCn3cccn3)CC2)c(C)o1 +CC(C)COc1ccc(C(=O)N2CCOCC2)cc1Br +COCc1cc(C(=O)OC2CCCC(OC)C2)ccc1F +O=C(Nc1ccc2[nH]c(=O)[nH]c2c1)c1c(F)cccc1Cl +Cc1nc(-c2ccc3c(c2)CCN3C(=O)CN2CCOCC2)cs1 +CCNC(=O)CSc1nnc(-c2cccc(Cl)c2)n1CC +Cc1nc(CNC(=O)CCn2nc3ccccn3c2=O)c(C)s1 +CCC1CCCN(C(=O)c2c[nH]c(C)cc2=O)CC1 +CC(c1ccccn1)N(C)S(=O)(=O)c1ccc2c(c1)CCCC2 +COCCOc1cc(C)ccc1NS(=O)(=O)c1ccc(C)cc1 +Cc1ccccc1C(C)NC(=O)N1CCN(C(=O)c2ccco2)CC1 +Cc1cnc(C(=O)N2CCc3ccccc32)c2cccc(N)c12 +COc1ccc(Cl)cc1NC(=O)c1ccon1 +COc1cc2nc(-c3ccccc3N)[nH]c2cc1OC +OCc1nnn(Cc2ccccc2F)c1C1CCCCC1 +Cc1cc(NC(=O)N2CCC(OCc3ccccc3C)CC2)ccn1 +O=C(COc1ccc(-c2ccccc2)cc1Cl)NCCCO +O=C(Cn1cnc(C2CCC2)cc1=O)Nc1ccc2c(c1)OCCO2 +Cc1ccc(C#N)cc1NCC(=O)N1CCCCC1C +CC1Cc2ccccc2N1CC1=NC(=O)C2Oc3ccccc3C2=N1 +Cc1nc(C2(NC(=O)NCC3(c4ccccc4)CC3)CCCC2)no1 +O=C(NCCc1cc2ccccc2[nH]1)c1ccc(-n2cnnc2)cc1 +CCN(Cc1cccc(Cl)c1)C(=O)CCC(=O)N1CCOCC1 +Cc1cc(C(=O)NC2(C)Cc3ccccc3C2)ccc1-n1cncn1 +CC1CCCC(NC(=O)c2ccc(S(=O)(=O)NC3CC3)cc2)C1 +COc1ccc2c(c1F)C(C1CCCN1C(C)=O)NCC2 +O=C(Cc1ccc[nH]1)NCc1ccnc(-n2ccnc2)c1 +O=C(NCC1CCCO1)Nc1c[nH]c2c(Cl)cccc2c1=O +Cc1cccc(C(=O)N2CC(OCc3ccc(F)cc3)C2)c1 +NC(=O)CCCn1ncc(N2CCCCC2)cc1=O +O=C(Cc1cn2ccccc2n1)NCc1ccccc1F +CCc1cccc(C)c1NC(=O)Cn1c2c(sc1=O)CCCC2 +O=C(NCC1(O)CCCc2ccccc21)c1cc(-c2ccccn2)no1 +CCOc1cccc(CNC(=O)Cn2cccn2)c1 +Cc1cc(C(=O)OC2CCCCCC2)nc2c1c(=O)n(C)c(=O)n2C +Cc1cc(C(=O)N2CCN(CC3=CCCOC3)CC2)c(C)o1 +CC(CCc1ccc2c(c1)OCO2)OC(=O)c1cnn(C)c1 +Cc1ccc(C(=O)NCc2cn(-c3ccccc3)nn2)cc1 +CCOC(=O)C1CCCCN1C(=O)COC(=O)c1ccc(C#N)cc1 +Cc1c(C(=O)NC(C(N)=O)C(C)(C)C)oc2c1C(=O)CC(C)(C)C2 +CCOC(=O)CSc1ncnc2c1nnn2C +COc1cncc(-c2nc3cc(Cl)ccc3[nH]2)n1 +Cc1c(C(=O)NCc2cccnc2-n2cccn2)[nH]c2c1C(=O)CCC2 +O=C(Cc1ccc(NC(=O)c2cc3ccoc3s2)cc1)NC1CC1 +CC1Oc2ccc(C(O)CCO)cc2N(C)C1=O +C#Cc1cccc(N(C)C(=O)CS(=O)(=O)N(CC)CC)c1 +CC(C)Sc1ccc(C(=O)Nc2nccs2)cc1 +O=C(NCCC(=O)N1CCc2ccc(Cl)cc2C1)C1CCCCC1 +CC(c1ccco1)N1CCN(C(=O)OC(C)(C)C)C(C)C1 +Cc1csc(C2CCN(c3ncccn3)CC2)n1 +CCOc1ccccc1N1CCN(Cc2cnc3ccccn23)CC1 +COc1ccccc1N1CCC(C(=O)N2CCCC2)C1=O +CNC(=O)Nc1ccc(NC(=O)Cc2ccc(OC(F)F)cc2)cc1 +CC(C)CC(=O)NCC1(c2ccccc2)CCOCC1 +COC(=O)c1cc(C#N)c(=O)n(Cc2ncc(-c3cccs3)o2)c1 +CCCOCC(=O)NCC(C)(O)c1ccsc1 +CCC(=O)Nc1ccc(NC(=O)Cn2nnc3ccccc32)cc1 +CCC(C)C(=O)NCC(=O)NC(C)c1ccc(Br)cc1 +O=C(OCC(=O)N1c2ccccc2NC(=O)C12CCCC2)C1CCC1 +COc1ccccc1Oc1ncnc(Oc2cccnc2)c1N +Cc1ccc2ncc(C(=O)NCc3cnn(Cc4ccccc4)c3)n2c1 +CC(=O)Nc1cc(NCC2CCOCC2)ccc1C +O=C(NC1CC1)c1ccc(NC(=O)C2CCCN2C(=O)C2CC2)cc1 +NC(=O)c1cc(Cl)ccc1NCc1ccccc1N +O=C(Nc1cnn(CC2CCCO2)c1)c1ccc(Cl)cc1O +CC(C(=O)NC12CC3CC(CC(C3)C1)C2)N1CCCC2(C1)OCCO2 +COCCn1nc(-c2ccc(Cl)cc2)cc(N)c1=O +CN1CCC(Oc2ccc(Br)cc2F)C1=O +Cc1ccc(C(=O)CCC(=O)Oc2cccc(C(N)=O)c2)s1 +COC(=O)c1ccc(COc2ccc3c(C)cc(=O)oc3c2)o1 +CCCc1cc(C(=O)N2CCCCC2c2nc3ccccc3[nH]2)[nH]n1 +O=C1CCC2C(CCN2Cc2nccs2)N1c1cccnc1 +CN1CC(CNc2ccc3ccccc3n2)CC1=O +CC(=O)Nc1ccc(Sc2nc3ccccc3n3nnnc23)cc1 +O=C(NCCc1csc2ccccc12)C1CCCN1C(=O)C1CC1 +COc1ccc(S(=O)(=O)N2CC(NC(=O)C(C)C)C2)cc1 +CC(=O)NCC(=O)N1CCOC(CC2CCCCC2)C1 +CC(C)(C)NC(=O)CCC(O)c1ccc2c(c1)CCCC2 +COc1cc(NC(=O)COC(C)=O)cc(OC)c1OC +CC(C)c1ccc2c(c1)S(=O)(=O)N=C(NCc1ccco1)N2 +COCCN(CC(C)C)C(=O)c1cc(Br)cn1C +Cc1cc(C(=O)N2CCCC2C(=O)NCc2ccco2)sc1C +O=C(CCNC(=O)c1cc2sccc2[nH]1)NC1CCCCC1 +O=C(NCc1cccc(Cl)c1)Nc1cccc2c1OCCO2 +CN(C)C(=O)c1cc2cc(Cl)cc(Cl)c2oc1=O +CC1CC1c1ccc(CN(C(=O)c2ccc3[nH]nnc3c2)C2CC2)o1 +COCc1cc(=O)[nH]c2cc(NC(=O)c3ccccn3)ccc12 +COCCN1CCN(C(=O)C2CCCOC2c2ccccc2)CC1=O +COc1ccccc1-c1nc2sc(C)nn2c1CO +CCOC(=O)CCCOc1cc(Cl)ccc1F +CCCc1cc(C(=O)NCc2noc(C3CCCO3)n2)[nH]n1 +COCCN(CC(F)(F)F)C(=O)c1cc(-c2cnn(C)c2)on1 +CN(c1nc(CSc2nnc(Cn3cncn3)o2)cs1)C1CC1 +CSc1ccccc1NC(=O)Cn1nc(C(F)(F)F)cc1C +O=C(Nc1n[nH]c(Cc2cccc(F)c2)n1)c1cc[nH]n1 +CCn1nc(C)c(C(=O)NCC(C)Oc2ccc(Cl)cc2)c1C +CNC(=O)COc1ccc(C(=O)NC2CC2)cc1OC +COC(=O)Cc1c(C)nc(-c2cccc(F)c2)[nH]c1=O +COc1ccc(F)c(NC(=O)Cc2ccc(F)c(F)c2)c1 +Cc1nccc(CNC(=O)C(c2ccccc2)N2CCCCC2=O)n1 +Cc1noc(C)c1CNc1ccccc1C(=O)NC(C)(C)C +CCC(C(=O)OCc1ccccc1)N1CCC(=O)CC1 +CCC(C)n1ncc(C(=O)N(C)Cc2nnc(C)n2C)c1C1CC1 +CC1CN(Cc2c(C3CCCC3)[nH]c3ncccc23)CC(C)O1 +O=C(NCCc1cccs1)N1CCC(c2n[nH]c(C3CC3)n2)CC1 +c1csc(-c2nnc(CSc3ccc4c(c3)OCCCO4)o2)c1 +CCOC(=O)C(N)c1c(F)c(F)c(F)c(F)c1F +COc1cc(C(=O)N2CCCCC2C2OCCO2)ccc1C +CNC(=O)COc1cccc(NC(=O)NC(C)c2nc(C)cs2)c1 +CCn1nc(C)c2nc(C)nc(N3CCN(S(C)(=O)=O)CC3)c21 +COC1CCCC1OC(=O)CCc1ccccc1C +CC(C)(C)N(CCO)S(=O)(=O)c1cccc(Cl)c1 +CC(=O)c1cc(C(=O)NCCc2cccc(Cl)c2)cs1 +C=CCOc1cc(C(=O)NCc2ccccc2)cc2occc12 +COc1ccc(CC2CN(C(=O)c3cocn3)CCC2OC)cc1 +CCOc1ccc(OC)c(-c2cnn(CC)c(=O)c2N)c1 +CC(C)N(C)C(=O)NCC(c1cccc(F)c1)N1CCOCC1 +Cc1cc(NC(=O)CSc2nc3c(c(C)c2C#N)CCC3)n(C)n1 +O=C(NCC1Cn2c(-c3ccccc3)cnc2CO1)C1CC1 +CC1CCCN(C(=O)CCOC2CCOCC2)c2ccccc21 +Cc1cc(=O)oc2cc(OCC(=O)NC(C)(C#N)C(C)C)ccc12 +Cc1ccccc1-n1c(=O)[nH]c2ccsc2c1=O +CC(NC(=O)c1cncc(Br)c1)c1cccc(F)c1 +CCC(C)C(=O)NCCc1c[nH]c2ccc(OC)cc12 +O=C(CCCNC(=O)c1ccc(F)cc1F)NC1CCC(O)CC1 +N#Cc1ccccc1OCC(=O)NCC(O)c1ccccc1Cl +Cc1nc2c(NCc3ccc(C(=O)N4CCCC4)cc3)ncnc2o1 +CC1(C)CCCN1S(=O)(=O)Cc1cccc(N)c1 +Cc1noc2ncn(CC(=O)NC3CCCCC3)c(=O)c12 +CN(CCC#N)S(=O)(=O)NCCc1nc2c(F)cccc2n1C +COc1cc(OC)c2c(CO)cn(C(C)C(N)=O)c2c1 +COC(=O)c1cc(-c2ccc3c(c2)nc(C)n3C)[nH]c1N +CC(C1CC1)N(C)S(=O)(=O)c1ccc(N2CCOC2=O)cc1 +Cc1ncc(CN2CCCCCC2c2ccncc2)s1 +Cc1cc(C)cc(-c2nnc(SCCNS(C)(=O)=O)o2)c1 +CC(C)(C)CCNC(=O)CSc1nnc2n1CCCCC2 +CN(CC12CCCC1N(C)C(=O)CC2)C(=O)c1ccco1 +CCCCN(CC(N)=O)C(=O)Cc1ccc(F)c(Br)c1 +COCCCCSc1nc(-c2cc(F)cc(F)c2)n[nH]1 +CCNS(=O)(=O)c1cccnc1Nc1ccc(Cl)c(F)c1 +OCCN(CC(O)c1ccc(F)c(F)c1)c1ccccc1 +CC(C)c1cc(=O)n(CC(=O)Nc2ccccc2F)cn1 +COc1ccc(OCCNC(=O)c2ccccc2Cl)cc1 +O=C(CN1C(=O)CCOc2ccccc21)NCC1CCCO1 +COCc1cc(C(=O)N2CCC(C(N)=O)CC2)ccc1F +O=C(Nc1ccccc1F)c1cccc(N2CCCC2=O)c1 +COC(=O)c1cc(CNc2cn[nH]c(=O)c2Cl)ccc1OC +COc1ccc(CCNC(=O)c2cc(C(N)=O)cs2)cc1OC +O=C1CCN(C(=O)c2cc(F)c(F)cc2Cl)CCN1 +O=C(CCc1nc2ccccc2s1)OCC(=O)c1ccco1 +Cc1ccc(-n2cnnc2SCC(=O)N2CCCC(C)C2)c(C)c1 +CN(C)C(=O)N1CCC2(C1)CN(c1cccc(F)c1)C(=O)CN2C +Cc1nn(CC(=O)Nc2ccc3c(c2)CCC3)c(=O)c(C#N)c1C +O=c1[nH]cccc1C1NCCc2cc(Cl)c(O)cc21 +CC(C)CCOCCN1CCN(C(=O)c2ccc(O)cc2)CC1 +CCOCCC(=O)N1CC2c3ccccc3OCC2(CO)C1 +CC(=O)c1c(C)[nH]c(C(=O)N2CCN(Cc3ccccc3)CC2)c1C +CCOC(=O)CC1CCN(C(=O)OC(C)(C)C)CCC1=O +COc1ccc(OC(C)C(=O)NCC(O)c2ccc(F)cc2)cc1 +CC(C)(CNC(=O)c1ccc(N2CCNC2=O)cc1)N1CCOCC1 +Cn1c(N)c(C(=O)c2ccc(C#N)cc2)c(=O)n(C)c1=O +CCOC(=O)CC(NC(=O)c1ccc(C)cc1)c1ccccc1Cl +Cc1cc(C)c(C)c(OCC(=O)Nc2ccc(C(N)=O)cc2)c1 +O=C(c1cccc(F)c1F)N1CCC(OCc2ccccc2F)CC1 +CCn1cc(C(=O)N(C)Cc2cc(C)c(OC)c(C)c2)c(C(C)C)n1 +Cc1nc(-c2ccc(F)cc2)sc1C(=O)NC1CCCCNC1=O +COC(C)C(=O)Nc1cccc(NC(=O)NC2CCCCCC2)c1 +COc1ccccc1C(C)NC(=O)CSc1nc(C)cs1 +N#Cc1ccc(S(=O)(=O)NCCc2c(F)cccc2F)cc1 +CC(C)(C)OC(=O)N1CC2CCCN2CC1CO +CC(=O)c1cccc(NC(=O)c2cnc3ccccc3n2)c1 +Cn1c(SCc2cccnc2)nnc1-c1ccccc1F +CC(C(=O)NC(C)(C)C)S(=O)(=O)c1nccn1C +Clc1ccc(-c2noc(COc3ccccn3)n2)cc1 +CCNC(=O)c1cccc(NC(=O)CCC(=O)OC)c1 +COc1ccc(N(C)C(=O)c2cc(C)nc3c2c(=O)[nH]n3C)cn1 +COCc1ccc(C(=O)NCCCc2nc3ccccc3s2)o1 +O=C(CC1(Cn2cnnn2)CCCCC1)Nc1nnc(C2CC2)s1 +CCC(Nc1ccc(C(N)=O)cc1)c1ccc(O)cc1 +CC(C)C(=O)N1CCC(C(=O)Nc2ccc(C#N)c(Cl)c2)CC1 +Cc1ccc(NC(=O)c2cc(-c3ccncc3)[nH]n2)cc1C +Cc1nc(CCC(=O)N2CCOC(C(F)(F)F)C2)n[nH]1 +O=c1[nH]c(CN2CCOCC2)nc2scc(-c3ccco3)c12 +CC1CCCCN1S(=O)(=O)NCc1ccccc1Cl +CCOC(=O)C1(NS(=O)(=O)c2ccccc2OC)CCCC1 +COC(=O)c1ccc(C)c(S(=O)(=O)NCc2cn[nH]c2)c1 +Cc1cc(NC(=O)CNC(=O)c2ccoc2C)c2ncccc2c1 +NC(=O)c1ccc(NC(=O)CCc2nc(-c3ccco3)no2)cc1 +CSc1cccc(NC(=O)NCCN2CCNC2=O)c1 +O=C(NCc1ccco1)C1CCCN1C(=O)Nc1ccccc1F +CC(NC(N)=O)C(=O)NCCCC1CCCCC1 +COc1ccc(NC(=O)c2nc(C)sc2C(C)C)cn1 +Cc1ccccc1C1CCN(C(=O)CC2CCCO2)C1 +COc1ccccc1-c1cc(C(=O)NCC#Cc2ccccc2F)[nH]n1 +CC(C)(C)OC(=O)N1CCC(Oc2ccccc2)CC1 +COc1cccc(CNCC2(c3ccccc3F)CC2)c1OC +Cc1cc(N)ccc1NC(=O)CCCn1cccnc1=O +N#CC(C(=O)c1cccc(-n2cccn2)n1)c1ccccn1 +Cc1ccc(S(=O)(=O)NC(C)(C)C)cc1C(=O)N(C)C(C)C +CCc1noc(C2(NC(=O)c3cccc(N(C)C)c3)CCCCC2)n1 +CCc1ccccc1NC(=O)Cn1c(N)nc(CC)c(C)c1=O +COc1ccc(C(=O)NC2(c3ccc(F)cc3)CC2)c(N)c1 +CC(NC(N)=O)C(=O)Nc1ccc(N(C)C)nc1 +CC(C)N(C)C(=O)CN1CCN(C(=O)CN2CCOCC2)CC1 +COC(=O)C(C)CN(C)S(=O)(=O)c1c(C)noc1C +COc1ccccc1C1CC1C(=O)Nc1cccc(-c2cn[nH]c2)c1 +O=C(c1ccc(Cl)cc1)N1CCC(c2nnc(C3CC3)o2)CC1 +NC(=O)COc1ccc(CNc2cc(F)cc(F)c2)cc1 +Cc1nnc(NC(=O)NCC2(O)CCCCC2)s1 +Cc1ccc(S(=O)(=O)NC(C)C(N)=O)c(Br)c1 +Cc1nn(C)c(C)c1C(C)NC(=O)c1ccc(=O)[nH]c1 +COc1ccc(C(C)N(C)C(=O)C(C)c2ccsc2)cc1 +Cc1ccc2oc(C(=O)N3CCCC3c3cnn(C)c3)cc2n1 +CCn1c(SCC(N)=O)nnc1-c1cn(C)nc1OC +Nc1nc(NCCC(=O)NC2CCCCC2)cc(N2CCOCC2)n1 +O=C(CCn1ncc(=O)c2ccccc21)Oc1cccc(Cl)c1 +CN(C)C(=O)CCNC(=O)c1c(O)cc(F)cc1F +Cc1[nH]ncc1S(=O)(=O)Nc1cc(Cl)ccc1O +COCC(C)(CCO)NC(=O)Nc1ccc(C(C)=O)c(C)c1 +CC(=O)c1nnc(-c2cccs2)n1Nc1ccc(Cl)cc1 +O=C(c1cccnc1)N1CCC(c2nc3cc(F)ccc3[nH]2)C1 +CC(NCc1cccnc1)C(O)c1ccc(F)c(F)c1 +O=C(NCC(=O)N1CCc2sccc2C1)c1ccc(Cl)cc1 +Cc1cccc(-c2noc(CNc3ccccc3N3CCCC3=O)n2)c1 +CCCCCNC(=O)C1CC(=O)N(c2ccc(C)cc2)C1 +Cn1cc(-c2nnc(Nc3ccn(Cc4ccccc4)n3)s2)cn1 +Cc1nn(C)cc1-c1ccnc(N2CCOCC2)n1 +COCC(C)NC(=O)Cc1ccc(OC)c(OC)c1 +CCCCC(=O)Nc1ccc(S(C)(=O)=O)cc1C +CNC(=O)CC1CCN(C(=O)c2cccc(OCC(F)F)n2)CC1 +CCOc1ccc(F)c(C(=O)NCCc2cscn2)c1F +CCCc1nc(CN2CC(C)OC(C)C2)cs1 +CCOC(=O)c1cnn(C2CCCCC2O)c1C +Cn1cnc2c1c(=O)n(CC(=O)NCc1ccccc1)c(=O)n2C +CC(C)(C)n1cc(NC(=O)C2COc3ccc(F)cc3C2)cn1 +O=C(NCCn1ccc(-c2ccncc2)n1)c1cccc(F)c1 +CCCCN(C)C(=O)Cc1nc(-c2ccc(OC)cc2)no1 +Nc1cccc(NC(=O)c2ccc(O)c(Cl)c2)c1 +COc1ccc(C(=O)CSc2nnc(-c3cccnc3)n2C)cc1 +CC1CCN(C(=O)c2ccc(OCC3CC3)nc2)C(C)C1 +Cc1cccc(C(=O)NC(C#N)c2ccc3c(c2)OCO3)c1 +COc1cc(O)cc(O)c1C(=O)CC(O)c1ccccc1 +Cc1ccc2c(c1)N(C(=O)c1cnc(C3CCCO3)s1)CCC2 +CCc1ccc(NC(=O)c2cnn(-c3ccccn3)c2C)cc1 +CC(CC1CCCC1)C(=O)N1CCN(Cc2ccccn2)CC1 +c1cnc(NCC2COC3(CCCN(Cc4nccs4)C3)C2)cn1 +CCn1cc(C(=O)N2CCCC2c2cccc3c2OCCO3)cn1 +COc1ccc(OCC(=O)N(C)Cc2ccoc2)cc1 +CNC(=O)c1cccc(NC(=O)N2CC(C)CC(C)C2)c1 +COCCN(Cc1ccc2c(c1)OCO2)C(=O)c1sccc1C +COCCN(Cc1ccoc1)S(=O)(=O)c1cc(Cl)ccc1C +CN(CC(C)(CO)CO)C(=O)c1c(Cl)cccc1Cl +CC(=O)c1cccc(NCC(=O)N(Cc2ccccc2)C(C)C)c1 +COc1ccc(NC(=O)NCc2cccc(OC(F)F)c2)cc1 +COc1ncccc1C(=O)NC1CC(=O)N(C2CCCCCC2)C1 +Cc1cc(C)cc(NC(=O)c2ccc(S(C)(=O)=O)cc2)c1 +CCOC(=O)Cn1cnc2c(cnn2-c2ccc(C)c(C)c2)c1=O +Cc1cc(C)c(NCC(O)c2ccc(F)cc2)c(C)c1 +CCCC(=O)NCc1ccccc1Cn1ccnc1 +CN1CCC(C(=O)NCC(c2ccccc2)c2ccccc2)CC1=O +N#Cc1cn(C2CC2)c(=O)n(Cc2csc(-c3ccoc3)n2)c1=O +COc1cc(NS(=O)(=O)c2cc(F)ccc2F)cc(OC)c1 +Cn1cccc1C(=O)N1CCC(OCc2nc(C3CC3)no2)CC1 +CCC(C)NC(=O)Cn1nc(-c2ccc(C)c(C)c2)ccc1=O +Cc1nn(-c2ccccc2)c(C)c1NC(=O)c1ccnn1C +Cc1ccccc1CNC(=O)NC(c1ccccc1)c1nccn1C +Cc1ccc(Cl)cc1NCc1c(CO)cnc(C)c1O +O=C(Nc1ccn(CCc2ccncc2)n1)C1CC1c1ccccc1 +Nc1cc(N)nc(SCC=Cc2ccccc2)n1 +Cc1csc(=O)n1CCC(=O)Nc1ccc2[nH]c(=O)[nH]c2c1 +COCCNc1ncnc(Nc2ccccc2C(F)(F)F)c1N +COC(=O)c1nn(C)c(N)c1-c1ccccc1Cl +COc1ccc(N2CC(NC(=O)Nc3nccs3)CC2=O)cc1 +CCCc1ccc(NC(=O)c2cc(N)cn2C)cc1 +CC1(CNC(=O)NCC(O)c2c(F)cccc2F)CCCC1 +COCc1ccccc1CNC(=O)c1cnc(C2CCCO2)s1 +CCC(C)C(C)NC(=O)NC1CCN(C(=O)OC)CC1 +Cn1cc(COC(=O)CCC(=O)c2ccc(F)cc2)cn1 +CC(Oc1cccc(C(C)C)c1)C(=O)Nc1ccc(=O)n(C)c1 +Cn1cccc1C(=O)N1CCC(C(=O)c2ccccc2)CC1 +CCc1ccccc1NC(=O)c1cc(C)n2nc(C)cc2n1 +c1cn2cnnc2c(NCc2ccc3c(c2)OCCO3)n1 +Cc1ccc(NC(=O)C(C#N)Cc2ccccn2)cc1 +CC(CCc1ccc(O)cc1)NC(=O)Nc1cnn(CC(N)=O)c1 +CSc1ccc(S(=O)(=O)NCCc2ccccc2)cc1 +Cc1ccc(-c2cc(C(=O)NCc3c(C)cc(C)[nH]c3=O)[nH]n2)cc1 +O=C(C1COc2ccccc2O1)N1CCCCCC1 +O=C(Nc1nc2c(s1)CCC2)c1csc(-c2ccccn2)n1 +Cc1ccccc1NS(=O)(=O)c1ccc(C(=O)NCC(C)C)cc1 +CCCNC(=O)CN(C)C(=O)CNc1ccc(C)c(C)c1 +CCS(=O)(=O)N1CCN(C(=O)c2cn(C)nc2C(C)(C)C)CC1 +CC(C)Oc1ncccc1NC(=O)Cc1cccc(OCC#N)c1 +Cc1cc(C(=O)Nc2cc(Cl)ccc2C)c(C)o1 +Nc1nccnc1C(=O)OCc1cc(-c2ccccc2)no1 +O=C(Cn1ccc(C(F)(F)F)n1)Nc1ccccn1 +CC(=O)Nc1ccc(CC(=O)N2CCC(OCC(C)C)CC2)cc1 +CC(=O)Nc1ccc(S(=O)(=O)Oc2cc(C)nc3ncnn23)cc1 +CCCc1nnc(NC(=O)NC(C)C(=O)N2CCCCC2)s1 +CC(NC(=O)c1scnc1C1CC1)c1ccc2c(c1)OCO2 +O=C(OCC1CC(=O)N(C2CC2)C1)c1coc2ccccc12 +O=C(NC1CCCN(c2ccccc2)C1=O)c1ccnc2ccccc12 +CNC(=O)NCC(=O)NC1CCC(C)(C)c2ccccc21 +O=C(NCc1cc(=O)[nH]c(N2CCCC2)n1)c1ccccc1F +Cc1ccc(NC(C)C(=O)NCCc2cccs2)cc1C(N)=O +CCCC(C)C(=O)N1CCN(Cc2nc(-c3ccsc3)no2)CC1 +CN(CCC#N)S(=O)(=O)N1CCCC1CC(=O)c1cnn(C)c1 +CCc1ccc(C(=O)NC2CC3C(=O)NC(C(C)C)C(=O)N3C2)cc1 +CS(=O)(=O)N1CCN(C(=O)NCc2cscn2)CC1 +CNC(=O)C1(C)CCCN1C(=O)c1cnc(N)nc1C +NC(=O)c1cc(C2CCCN(C(=O)CCCc3cccs3)C2)n[nH]1 +CCN(C(=O)c1cc(F)ccc1C)C(C)C(C)C +COC(=O)C1=C(C)NC(C)=C(C(=O)OC)C1c1ccc(C#N)cc1 +C=CCN1CCN(S(=O)(=O)c2c(C)noc2C)CC1 +CC1COCC(C)N1C(=O)c1cnc(C2CCCO2)s1 +CC1CC1C(=O)Nc1ccnn1Cc1cnn(-c2ccccc2)c1 +CCCNC(=O)CCCC(=O)NC1(C)Cc2ccccc2C1 +O=C(Oc1ccc2c(c1)OCO2)c1cc(Cl)ccn1 +Cc1c(C(N)=O)nnn1Cc1c(F)cccc1Cl +CCCS(=O)(=O)N1CCCC1C(=O)N1CCCCC1C +N#CCCN(Cc1ccccc1)C(=O)COc1ccccc1Cl +CC(C)(C)OC(=O)N(Cc1ccccc1)S(C)(=O)=O +CCOC(=O)N1CCN(Cc2csc(Nc3ccccc3)n2)CC1 +COCC(=O)Nc1ccc2oc(-c3ccc(C)cc3)cc(=O)c2c1 +Cc1noc(C)c1CNC(=O)N(C)Cc1c(C)noc1C +Cc1cc(-n2ccnc2C)n2ncc(-c3ccccc3)c2n1 +NC(=O)Nc1cccc(NC(=O)C2CC2c2ccc(Cl)cc2)c1 +CCOc1ccccc1OC(=O)Cc1c[nH]c2ccccc12 +CCn1nnnc1-c1cccc(C(=O)NC2CCCC2)c1 +CC(C)CNC(=O)CSc1nc(C=Cc2cccs2)n[nH]1 +O=S(=O)(CCCOc1ccc2c(c1)OCO2)NC1CCCC1 +CCn1nnnc1SCC(=O)c1c(C)c(C)cc(C)c1C +COCCn1cc(NC(=O)N(C)Cc2cccnc2)cn1 +COCCC(=O)N1CCC(Oc2ccccc2OC)CC1 +Cc1cnc(CCNC(=O)CC(NC(N)=O)c2cccs2)s1 +CN(CCC#N)C(=O)Nc1ccc(OC2CCCC2)c(Cl)c1 +CC(O)CNC(=O)C1CC(=O)N(c2ccc(F)cc2F)C1 +O=C(c1cn2ccsc2n1)N1CCN(c2ccccc2)C(=O)C1 +CCN(CC)C(=O)c1cn(CCC#N)nc1-c1ccc(F)cc1 +Cc1nc2ccccc2c(=O)n1CC(=O)N1CCCc2ccccc21 +COc1ccc2nnc(CCC(=O)Nc3nc4c(s3)CCC4)n2n1 +CCCn1nc(C)c2[nH]c(-c3cnn(C(C)C)c3)nc21 +CN1CCSc2ccc(C(=O)NCc3ccc4c(c3)OCO4)cc21 +Cc1ccc(C(=O)COC(=O)c2cccc(O)c2)s1 +Cc1ccc(Cl)c(NC(=O)Cc2csc(C)n2)c1 +N#Cc1ccccc1NC(=O)Cn1c(=O)cnc2ccccc21 +Cc1cccc2nc(COc3cccc(C#N)c3)cc(=O)n12 +CCC(=O)OC(C)C(=O)c1ccc(NS(C)(=O)=O)cc1 +Cc1noc(C(C)C)c1C(=O)N1CCOC(c2ccccc2)C1 +CCCC(=O)Nc1cc(-c2nnc3n2CCCCC3)ccc1F +Cc1cc(SCc2nc(N)nc(N(C)C)n2)nc(C)n1 +Cc1ccccc1OCCN1CCN(CC(=O)NC(C)C)CC1 +CC(OC(=O)c1ccncc1)C(=O)N(C)c1ccccc1 +O=C(CCn1ncc2ccccc21)NCc1cccs1 +CCCCS(=O)(=O)N1CCC(C(=O)NCc2ccco2)CC1 +CC(C)Cc1ccc(C(C)C(=O)N(C)CCO)cc1 +CCn1nc(C)cc1C(=O)Nc1nnc(-c2ccno2)o1 +C#CCSc1nnnn1-c1ccc(Br)cc1 +CC(C)c1ncc(Cl)c(C(=O)NC(C)C2COc3ccccc32)n1 +Cc1ncc(CNC(=O)c2cn(C)nc2C(F)(F)F)s1 +COc1ccc(C(=O)Nc2ccc(C(C)=O)cc2)c(N)c1 +Nc1cnc2ccc(C(=O)N3CCN(c4ccccc4)CC3)cn2c1=O +Cc1nn(C)c(C)c1NS(=O)(=O)c1c(C)noc1C +O=C(NCCC(=O)N1CCOCC(CO)C1)c1ccccc1F +Cn1c(=O)c(C(=O)NCc2ccccc2)cc2cccnc21 +CCOc1cc(CNC(=O)CCc2nc3ccccc3[nH]2)ccc1O +Cc1cc(C(=O)NCc2ccnc(OCc3ccccc3)c2)on1 +COCCOc1ccc(NC(=O)Nc2cnn(C)c2)cn1 +Cc1csc(SCC(=O)N(CCC#N)c2ccccc2)n1 +CN(C)C(=O)c1ccc(NC(=O)c2ccc(C#N)cc2)cc1 +Nc1cc(C(=O)Nc2cc(Br)ccc2F)ccn1 +COC(=O)c1ccsc1NC(=O)c1cn(-c2ccccc2)nn1 +CCN1CC(C(=O)Nc2cc(OC)ccc2F)CC1=O +CCC(NC(=O)CNC(=O)OC)c1ccc(Br)cc1 +Cc1nc(-c2cc(C(=O)Nc3nncs3)n(C)c2)cs1 +CC(C)c1cnc(-c2ccc(NC(=O)NCc3ccon3)cc2)o1 +O=C(CCS(=O)(=O)c1ccc(Cl)cc1)NCC(=O)NC1CC1 +CC1CCCCN1c1ncnc(NCc2cccnc2)c1N +Cc1csc(C(C#N)C(=O)c2c(C)nn3c(C)cc(C)nc23)n1 +CCCCOc1ccc2c(c1)C(c1ncccn1)NCC2 +CC(NC(=O)CN1CCOCC1C)c1ccc(Cl)c(Cl)c1 +Cc1c(Cl)cccc1NC(=O)CSc1nnc(C2CC2)n1C +COc1ccc(C(O)C(=O)c2ccc(OCCO)cc2)cc1 +CCn1cc(-c2cc(=O)n3nc(-c4ccccc4)c(C)c3[nH]2)cn1 +CCn1cc(CN2CCNC(=O)C2c2ccccc2Cl)cn1 +O=C(Nc1ccc2nc[nH]c(=O)c2c1)c1ccc(-n2cnnn2)cc1 +O=C(CNC(=O)c1cccnc1SC(F)F)NC1CC1 +CCOC(=O)c1noc2nc(C)nc(NCc3ccc(CC)cc3)c12 +CCC(C)c1ccccc1NC(=O)C(C)NC(C)=O +Cc1nccn1-c1ccc(C(=O)Nc2cccc(Cl)c2Cl)nn1 +COc1ccccc1CC(=O)N(C)Cc1cc(C)on1 +CCOc1cc2c(cc1O)C(c1nc[nH]n1)NCC2 +CC(=O)c1cc2cc(C(=O)NCc3ccccc3Cl)cnc2[nH]1 +COc1ccc(C)cc1CC(=O)N1CC(=O)Nc2ccccc21 +Cc1cnc(C(=O)Nc2nc(-c3cc(C)oc3C)cs2)cn1 +CC(=O)c1ccc(-c2ccccc2Br)[nH]1 +Cc1cc(NC(=O)CC(C)(C)C)ccc1S(N)(=O)=O +CC(=O)Nc1cccc(NCCOc2cccc(N)c2)c1 +CCc1ccc(-c2csc(NC(=O)c3c(C)nn(C)c3C)n2)cc1 +Cc1csc(CNC(=O)NCCOc2ccc(F)c(F)c2)n1 +CN(C)C(=O)CCc1nnc(Cc2ccc(-c3ccccc3)cc2)o1 +Cc1cc(C(=O)Nc2ccc(C(=O)NC3CCCC3)cc2C)[nH]n1 +CCCc1nc(CN(CC)C(=O)c2cc(F)c(F)cc2Cl)no1 +Cc1ccc(NC(=O)c2ncc3n2CCCC3)cc1C +COc1cc(COC(=O)c2sc(-c3nc[nH]n3)nc2C)ccc1C +Cc1cc(Cn2c(C(F)(F)F)ccc(C(N)=O)c2=O)on1 +COC(=O)c1cc(CNC(=O)CC2CC3CCC2C3)ccc1OC +O=C(CCC(=O)c1ccccc1)Nc1ccc(-c2cc[nH]n2)cc1 +CCn1ncc(C(C)NS(=O)(=O)c2ccc(C)cc2)c1C +COc1ccccc1CNS(=O)(=O)Cc1ccc(F)cc1 +Cc1nc2c(s1)CCCC2NC(=O)c1cc(-c2ccccc2)on1 +CC(=O)Nc1cc(NC(=O)c2coc(-c3ccccc3)n2)ccc1F +CN(C)C(=O)c1cccc(OCC(=O)Nc2cccc(Cl)c2)c1 +Cc1ccc(C2C(C(=O)NCC(C)C)CCC(=O)N2C)cc1 +COc1ccnc(NC(=O)Cn2ccc3ccccc32)c1 +COc1cc(C2NC(=O)c3cccnc3N2)cc(Cl)c1O +COc1ccc(-n2cnnn2)c(NC(=O)c2ccc(F)cc2)c1 +C#Cc1cccc(NS(=O)(=O)c2cccc3cc(C)cnc23)c1 +CCc1[nH]c(=O)c(C(=O)Nc2ccc(OC)cc2)cc1C(=O)OC +CS(=O)(=O)N1CCCCC1C(=O)Nc1ccc(Cl)cn1 +CCC1CN(C(=O)c2cc(C3CC3)nc3c2c(C)nn3C)CCO1 +N#Cc1ccc(CSc2nc(C3CCCC3)n[nH]2)cc1 +COc1ccc(C(O)CNC(=O)C(C)C)c(OC)c1 +CC1(C)CS(=O)(=O)N(c2ccc(C(C)(C)C)cc2)C1=O +CCCOc1cccc(NC(=O)NCc2nnc3ccccn23)c1 +COC(=O)CN(C(C)C)S(=O)(=O)c1ccccc1 +CN1C(=O)CCc2cc(NC(=O)c3ccncc3)ccc21 +Cc1nn(-c2ccc(F)cc2)c(C)c1C(=O)NCC1CCCO1 +O=C1CCCN1c1cccc(NCc2cc3ccccc3[nH]c2=O)c1 +CCOCCCNC(=O)c1cc2c(=O)oc3ccccc3c2n1CC +CCn1ncc2[nH]c(-c3cc(OC)c(OC)cc3OC)nc21 +COc1ccc(C(=O)Nc2ccc(NC(C)(C)CO)nc2)cc1OC +CCCOc1ccc(NC(=O)NCc2nnc3ccccn23)c(C)c1 +NC(=O)CC1CCN(C(=O)NCCc2ccc(F)cc2F)CC1 +Cc1ncsc1CN1CCCN(C(=O)c2ccc(Cl)cc2)CC1 +CCC(Oc1ccccc1)C(=O)NCc1nc2ccccc2n1C +O=C(COc1ccccc1)N1CCC(S(=O)(=O)c2ccccc2)C1 +O=C(CCOc1ccccc1)NCc1nnc2ccccn12 +CCOc1ccc(Cl)cc1CNc1cccnc1 +N#Cc1cccn2nc(Cc3ccc(O)cc3)nc12 +CCC(=O)N1CCCC(C(=O)Oc2ccc(OCC3CC3)cc2)C1 +COc1ccc(CCNC(=O)c2cc3ccccn3n2)cc1OC +COc1ccc(F)cc1S(=O)(=O)NCc1cnn2ccccc12 +CC(C)c1ncc(Cl)c(C(=O)NCc2ccsc2)n1 +CCN1CCN(C(=O)c2cn(-c3ccc(C)cc3)nn2)CC1 +CC(=O)Nc1cc(-c2nnc3n2CCCCC3)c(F)cc1F +CC(=O)c1cc(C)cc(NC(=O)OC(C)(C)C)c1O +Cc1cccc(C(=O)N2CCN(CCC#N)CC2)c1 +O=S(=O)(c1ccc(Br)cc1)N1CCn2ccnc2C1 +O=C(Cc1ccc[nH]1)Nc1ccc2c3c(cccc13)CC2 +COCCCCCNC(=O)N1CCN(c2ncccn2)CC1 +Cc1ccccc1NCCC(=O)NCC1CCOC1 +Cc1ccc(N2CCCS2(=O)=O)cc1NC(=O)NC(C)(C)C +COc1ccc(Nc2nc3ccccc3[nH]2)cc1OC +Cc1ccc(-n2cnnc2SCC(=O)Nc2ccccn2)cc1C +O=C(NCc1ccco1)Nc1cccc(C(F)(F)F)c1 +C=CCn1c(=O)c(=O)n(C(C)C)c2ccc(C(F)(F)F)cc21 +O=C1C(Sc2ccc(Cl)c(Cl)c2)CCN1C1CCOCC1 +Cc1cc(C(C)NC(=O)c2nc3nccc(C)n3n2)c(C)s1 +CCN1CCc2nc(NC(=O)c3sccc3C(C)C)sc2C1 +CS(=O)(=O)NCC1(c2cccc(Br)c2)CC1 +Cc1cccc(OC(=O)Cc2ccc(-n3cnnn3)cc2)c1 +Cc1cccc(C(=O)Nc2cnn(CC3CC3)c2)c1 +Cc1nn(CCO)c(C)c1CN1CCN(C2CCCCC2)C(=O)C1 +Cc1nc(C(=O)N2CCOC(C3CCCO3)C2)cs1 +COc1ccc(NC(=O)c2cnc3ccccc3n2)cc1 +CCOC(=O)N1CCC(C(=O)Nc2nccs2)CC1 +O=C(NCc1cc(Cl)c2c(c1)OCCCO2)C1CCC1 +O=C(Nc1nnc(C23CC4CC(CC(C4)C2)C3)s1)c1cccnc1 +CC(Cn1nc(-c2ccco2)ccc1=O)C(=O)Nc1ccccc1C#N +COC(=O)c1nnn(-c2cccc(C)c2)c1C(=O)OC +O=C1NC2(CCN(C(=O)c3cccs3)CC2)CC1c1ccccc1 +N#Cc1ccc(C(=O)N(Cc2cccs2)CC2CCCO2)cc1 +COc1cccc(CSc2nc(C)cc(N)n2)c1 +COc1cccc(CO)c1OCCC(=O)N(C)C +CNC(=O)c1ccc(NC(=O)c2ccc(F)c(NC(C)=O)c2)cc1 +CC1CCCCC1NS(=O)(=O)c1cnn(C(C)C)c1N +O=C(CCc1ccccn1)NCCc1ccc(O)cc1 +O=C(CCNC(=O)C1CCCC1)Nc1cc(F)cc(F)c1 +Cc1noc2nc(-c3ccco3)cc(C(=O)Nc3ccccn3)c12 +O=C(NCC1(c2ccccc2)CCC1)c1cnc2sccn2c1=O +NC(=O)c1cc(S(=O)(=O)N2CCCCC2)ccc1Cl +Cc1ccc(OCC(C)NC(=O)N2CCC(C(N)=O)CC2)cc1 +CC(OC(=O)c1[nH]nc2ccccc12)C(=O)NC1CCCCC1C +CCCCS(=O)(=O)NCC(=O)Nc1ccc2[nH]c(C)cc2c1 +CCOc1cc2c(cc1CNCC1CN(C)CCO1)OC(C)C2 +OCCc1cnn(CCCc2ccc(Cl)cc2)c1 +Cc1ccc(C)c(Cn2ccnc2CN(C(=O)C2CC2)C(C)C)c1 +NC(C(=O)NCc1ncc[nH]1)c1cc(F)cc(F)c1 +CCOc1ccc(F)c(C(=O)N(CC)C2CCCC2)c1F +O=C(NCc1cccnc1-n1cncn1)C1CCOC1 +N#Cc1cnn2ccc(-c3ccc4c(c3)CCC4)nc12 +O=C(NCc1ccncc1)c1cc2cccnn2n1 +Cn1cc(CC2CCN(C(=O)NCc3nnc4ccccn34)C2)cn1 +CCN(C)C(=O)c1ccc(S(=O)(=O)N(CC)c2ccccc2)cc1 +Cn1nccc1NC(=O)c1ccc(Cl)cc1O +COc1cc(CNc2cnn(C(C)(C)C)c2)cc(OC)c1 +Cc1ccc2nc(NC(=O)CNC(=O)OCC(F)(F)F)sc2c1 +COc1ccc(-c2nc(CC(=O)NCc3ccco3)sc2C)cc1 +CCC1CCCC(NC(=O)NCc2ccc(S(N)(=O)=O)cc2)C1 +COc1cc(OC)c(-c2cc(C(C)=O)c(C)o2)cc1OC +CC(OC(=O)c1cncc(Br)c1)c1ccccn1 +CC(C)OC(=O)CSc1nc(C2CCCC2)n[nH]1 +Cn1cnnc1S(=O)(=O)CC(=O)Nc1ccc(C(C)(C)C)cc1 +O=C(N1CCCC1c1nc(C2CC2)no1)C12CC3CC(CC(C3)C1)C2 +CCCn1cnnc1C1CCCN(C(=O)c2cc(C3CC3)n[nH]2)C1 +Cc1nn(C)cc1CN(C)S(=O)(=O)c1cnn(C(F)F)c1C +Cc1ccc2oc(C(=O)Nc3ncccn3)cc(=O)c2c1 +CCc1ncc(C(=O)NC2COCC2Cc2cc(C)no2)cn1 +Cc1c(C(=O)Nc2ccc(F)cc2)cnc2ccnn12 +Cc1ccccc1SCC(=O)Nc1ccccc1C#N +CCC1CCCCN1C(=O)NCCCS(=O)(=O)c1ccccc1 +Cc1nccc(C(=O)NCc2nn(-c3ccccc3)c3c2CCC3)n1 +Nc1nc2scc(-c3ccc(Br)cc3)n2n1 +CCn1nc(C(=O)NC2CCCC2)cc1-c1ccc2c(c1)OCO2 +Cc1cccc(NC(=O)C2CC(=O)N(c3cnn(C)c3)C2)c1 +CCCS(=O)(=O)N1CCN(Cc2nc(N)c3ccccc3n2)CC1 +Cc1ccc2oc3c(c(=O)c2c1)C(c1cccc(O)c1)N(C)C3=O +Cc1c(Cl)cnn1CC(=O)NCC(F)(F)F +O=C(Cn1cnnn1)Nc1ccc(-c2nc3ccccc3s2)cc1 +O=C(Nc1ccncc1)N1CCC(Oc2ccc(F)cc2F)CC1 +CC(C)(C)OC(=O)NCc1ccc(CCO)cc1 +CCC(OC(=O)c1c(C)nn2cccnc12)c1ccc(C)cc1 +CCC(C)(C)OC(=O)c1cc(N2CCCC2=O)ccc1F +Nc1c(Cl)ccn2c(-c3ccccc3F)nnc12 +O=C(NCCc1ccc(OC(F)(F)F)cc1)C1CC=CC1 +CC(C)N(Cc1ccc(Cl)c(Cl)c1)C(N)=O +CCCC1CN(C(=O)c2cc(S(=O)(=O)N(C)C)oc2C)CCO1 +CCOC(=O)CCSc1nc2c(c(C(F)(F)F)c1C#N)CCC2 +Cc1ccc(CCCC(=O)NC2(C#N)CCC3(CC2)OCCO3)cc1 +CCOc1ccc(S(=O)(=O)N(C)c2ccccn2)cc1OCC +COc1ccc(O)c(C(=O)c2cnn(-c3ccccc3)c2)c1 +COc1ccc(-c2nccn3cc(C(=O)NC4CC4)nc23)cc1 +CN(C)c1ccccc1NC(=O)NCC(C)(C)C(N)=O +COCc1ccccc1C(=O)NCCC(=O)N1CCN(C(C)=O)CC1 +CSc1cccc(C(=O)Nc2ccc3sc(C)nc3c2)c1 +Cc1ccc(S(=O)(=O)N2CCCC2C(=O)OC2CCCC2)s1 +Cc1c(F)cc(C#N)cc1NCC(=O)NCC(F)(F)F +Cc1cc(C)n(CCCNC(=O)c2cc(C3CC3)nc3ccccc23)n1 +Cc1cccc(C(NC(=O)c2cnc(C)nc2C)c2cccs2)c1 +Cc1nnc(CN(C)CC2COc3ccccc3O2)n1C +CC(CN1CCOCC1)NC(=O)c1cccnc1N1CCCC1 +COc1ccc2c(ccn2CC(=O)NC2=CC3N=CC=C3C=C2)c1 +CCOc1ccc(OCc2nc(CCO)cs2)cc1 +COc1ccc2c(ccn2CC(=O)OC2CCCC2OC)c1 +Cc1ccc(C(=O)N2CCC(c3nnc(C4CC4)o3)CC2)cc1 +Cc1cc(S(=O)(=O)NCCc2ccccc2)c(C)s1 +COc1ccc(NC(=O)Cn2ncccc2=O)cc1 +CCOC(=O)C(NC)c1c(Br)cnn1C +C#CCCOC(=O)CCc1c(C)[nH]c(=O)c(C#N)c1C +COc1ccc(CNc2ccc(C)cc2C)cc1O +Cc1nn(C)c(C)c1CC(C)NC(=O)N1CCCC1CO +O=C1N(Cc2cccnc2)CCN1c1ccc(F)c(Cl)c1 +CC(=O)c1cc(C(=O)OCc2nc(-c3ccccc3)no2)n(C)c1 +CCOc1ccc(S(=O)(=O)NC)cc1NC(C)=O +CCc1ccccc1CNC(=O)N1CCC(N(C)C(C)=O)CC1 +Cc1nc2c(c(C)nn2C)c(C)c1CCC(=O)Nc1ccccc1 +COC(=O)CCCC(=O)N1CCC(C(F)(F)F)CC1 +Cc1ccc(C(C)NC(=O)CNC(=O)OC(C)(C)C)s1 +CCc1onc(C)c1NC(=O)CCc1ccc2c(c1)OCCCO2 +COc1ccccc1C(O)c1ccc2c(c1)OCO2 +COc1ccc(NC(=O)NCc2cccs2)cc1 +O=C(Cc1ccon1)Nc1cccc(C(=O)c2ccccc2)c1 +CCN1CCOc2ccc(NC(=O)c3ccccc3)cc2C1=O +CCC1(CC)Oc2ccc(-c3cscn3)cc2NC1=O +O=C(Cc1c(Cl)cccc1Cl)Nc1cccc(CO)c1 +N#Cc1ccc(OCCSc2nc(N)nc(N)n2)cc1 +O=C(C1CC1)N1CC(C(=O)N2CCCC2)C(c2ccc(F)cc2)C1 +CC(C)CCn1ncc(-c2ccc(F)c(F)c2)c(N)c1=O +COc1ccc2c(c1)nc(C#N)n2CC(F)(F)F +O=C(C1CCN(S(=O)(=O)c2cccnc2)CC1)N1CCOCC1 +CCn1nc2c(cc1=O)CN(c1ccc(C#N)cn1)CC2 +COC(CNS(=O)(=O)c1cc(F)ccc1F)c1cccc(F)c1 +CCC(=O)NC1CCCN(c2ncnc3c2cnn3C)C1 +C#CCOC(=O)CSc1ccc(C(=O)CC)cc1 +O=C(c1cscn1)N1CCCC1c1ccncn1 +COc1ccccc1-c1nc2cnn(-c3ccccc3)c2[nH]1 +CCc1ccc(CNC(=O)NCc2ccc3c(c2)OCCO3)s1 +O=C(NC1CCCC1)c1nnn(-c2ccccc2)c1C(F)(F)F +CCNC(=O)c1ccc(NCC2CCOC2)c(C)c1 +Cc1cc(NC(=O)NCC(C)CC(C)O)ccc1C(=O)NC(C)C +CC(=O)NCc1ccc(C(=O)N(C)Cc2c(F)cccc2Cl)cc1 +Cc1c(S(=O)(=O)N2CCCCC2)cc(C(=O)n2ccnc2)n1C +C#CCN1CCC(C(=O)N(Cc2ccccc2)CC2CCC2)CC1 +CCN1CC(C(=O)NCCc2c[nH]c3ccc(OC)cc23)CCC1=O +CCCNC(=O)CN1CCN(Cc2ccccc2)C1=O +COCCN(CC(C)C)C(=O)NC1CCN(c2ccccc2)C1=O +CC(=O)NC(Nc1ncccn1)(C(F)(F)F)C(F)(F)F +COc1cccc2c1cc(C(=O)NCCn1cccn1)n2C +CCCNC(=O)CN1C(=O)CNc2cc(F)ccc21 +COc1ccccc1CCN(C)S(=O)(=O)c1ccccc1C#N +Cc1cc(Cl)cc(Cl)c1OCC(=O)NCc1ccco1 +O=C(NC1CC(=O)N(c2ccccc2)C1)C1CCC1 +CN(C)S(=O)(=O)N1CCN(Cc2cscn2)CC1 +Cc1occc1C(=O)Nc1cnn(CCN2CCOCC2)c1 +CC(C)(C)OC(=O)COC(=O)c1cc(=O)c2ccccc2o1 +CC1CN(CC(=O)NC(c2ccccc2)c2nccn2C)C(C)CO1 +CCCn1c(C)nnc1SCc1nc(C(F)(F)F)cs1 +Cn1ncc(-c2nc(Cc3cccs3)no2)c1N +O=C(Cc1cccs1)NCCNC(=O)c1ccc(Cl)cc1 +CC(=O)c1ccc(NC(O)C(Cl)(Cl)Cl)cc1 +COCCOc1ccc(NC(=O)NC(C)c2ccccc2)cn1 +COc1ccc(C(C)N(C)C(=O)Nc2ccc3c(c2)COC3)cc1 +CCN(CCCNC(=O)c1ccc(N(C)C)c(F)c1)C(C)=O +COc1ccc(-c2cn3c(nc4cc(N)ccc43)[nH]2)c2cccnc12 +Cc1ccc(CNC(=O)c2sc(-c3ncccn3)nc2C)s1 +CNS(=O)(=O)c1cc(C(=O)NCC2CCC2)n(C)c1 +O=C(NCCO)NCCc1cc(Cl)c2c(c1)OCCO2 +COCCNC(=O)c1nnn(-c2ccc(Br)cc2)c1C +COC(=O)CSc1ncn(-c2nc(C)cc(OC)n2)n1 +CC(CCc1ccco1)NC(=O)Cn1cnc2sccc2c1=O +CC(CO)NC(=O)Nc1ccccc1OC(F)(F)F +O=C(Nc1ccc2[nH]c(C(F)F)nc2c1)c1csnn1 +CC(C)n1c(=O)c2nscc2n(CC(=O)NCc2ccco2)c1=O +COc1ccccc1Oc1ncccc1CNC(=O)c1c[nH]nc1C +CCNC(=O)CSc1nc(=O)[nH]c(C)c1C(C)=O +CCCc1nc(-n2cccc2)sc1C(=O)N1CCNC(=O)C1 +CCCCC(=O)NCC#Cc1ccc(C(=O)N(C)C)cc1 +Cc1ccccc1CN1CCN(c2ccccc2N)CC1 +CC1c2cccn2CCN1C(=O)c1n[nH]c2ccccc12 +O=C(CCn1cnc2sccc2c1=O)NCc1ccc(F)cc1 +CC(c1ccccc1Cl)n1c(N)cc(=O)[nH]c1=O +CN(CC1CCOC1)c1ccc(Br)cn1 +CNS(=O)(=O)c1ccc(C)c(NC(=O)c2ccc(C)nc2)c1 +CCCC(=O)Nc1cccc(CNC(=O)N(C)CC2CCCO2)c1 +CC(NC(=O)c1ccc(O)cc1)c1ccc(N)cc1 +Cc1cc(S(=O)(=O)NC2CCC(O)CC2)ccc1Br +O=c1ncn(Cc2ccccn2)cc1-c1ccccc1 +Cc1noc(C)c1CN1C(=O)C2CCC1CN(c1ccnc(N)n1)C2 +O=C1N(Cc2ccc(F)cc2)CC2CN(Cc3cccnc3)CCN12 +N#CCn1ccc(NC(=O)Cc2ccc(F)cc2)n1 +CC(O)(CNS(=O)(=O)Cc1ccccc1)c1ccc2c(c1)OCO2 +Cc1[nH]nc(O)c1CC(=O)NCCn1c(C)cc2ccccc21 +Cc1cc2nc(C(C)O)n(CC(=O)N(C)c3ccccc3)c2cc1C +CC(=O)N1CCN(c2cc(Cl)ccc2C)C(=O)C1C +Cc1ncsc1COC(=O)c1ccc2c(c1)[nH]c(=O)n2C +O=C(NC1CC=CC1)NC1CCOC1c1ccc(Cl)cc1 +CC(C)NC(=O)c1ccc(NCC(=O)NC(C)(C#N)C(C)C)cc1 +CC(C)OCCOC(=O)C1(c2ccc(Cl)cc2)CC1 +O=C(NCC1CCC1)Nc1ccccc1OC(F)(F)F +COC(=O)c1cccc2c1CCCN2C(=O)c1ccc(C)nc1C +O=S(=O)(Nc1ccc(Br)cn1)c1ccc(F)cc1 +Cc1cc(C)c(NC(=O)c2cccc(N3CCCC3=O)c2)c(C)n1 +CC(=O)c1ccc(NC(=O)c2ccc(C)[nH]c2=O)cc1C +Cc1cccc(-c2csc3c(=O)n(Cc4ccccn4)cnc23)c1 +Cc1ccc(NC(=O)Cc2ccc(F)c(F)c2)cc1N1CCOC1=O +CC(C)CC(C)N(C)C(=O)Cn1cnc(C2CCC2)cc1=O +Cc1ccc2n1CCN(C(=O)CCn1nc3ccccn3c1=O)C2C +O=C(Cn1c(=O)[nH]c2ccccc2c1=O)N=c1[nH]c2ccccc2[nH]1 +O=C(CCn1nc(-c2ccccc2)ccc1=O)NC1CCCC1 +CN(C)c1ccc(C(=O)NC2CCc3c(O)cccc32)cc1 +CCOC(=O)Cn1nc(C(F)(F)F)c(Cl)c1C1CC1 +CNC(=O)c1cc(NCc2c[nH]nc2C)ccc1Cl +COc1ccc(C(O)CCc2nc(C)cs2)cc1 +CC1CCOC1C(=O)NC1(c2ccc(F)cc2F)CCOCC1 +Cc1cccc(CNS(=O)(=O)c2cccc(Cl)c2)n1 +CCn1ccc2nc(COC)cc(Br)c21 +FC(F)Cn1cc(NCC2(CN3CCOCC3)CCCCC2)cn1 +COc1ccc(C2(CNC(=O)NCC(C)C)CCOCC2)cc1 +COc1ccc(Br)c(CNC(=O)CCC2CCCO2)c1 +c1ccc(C2C3CCCCC3=Nc3nnnn32)cc1 +CNC(=O)Nc1cccc(OCc2ccccc2OC)c1C +CC(C)Oc1ncccc1NC(=O)CCc1nc(C2CCCC2)no1 +COc1c2c(cc3c1C(CC(=O)c1ccccn1)N(C)CC3)OCO2 +CC(C)CNC(=O)c1ccc(CSc2ncn[nH]2)cc1 +CC(C)(C)OC(=O)N1CCC(Nc2cnccn2)CC1 +CC(C)Oc1ccc(CNC(=O)c2cnn[nH]2)c(C(F)(F)F)c1 +Cc1nc(CC(=O)c2ccc(O)c(C)c2O)cs1 +COc1cccc(OCC(=O)Nc2ccccc2-n2cnnn2)c1 +Cc1[nH]c(C(=O)N(C)C)c(C)c1C(=O)OC(C)C +CS(=O)(=O)NCC1(Sc2ccccc2)CCOCC1 +CCCCS(=O)(=O)N1CCC(C(=O)Nc2cccc(C)c2)CC1 +COCC(NC(=O)NCc1cnc(C)s1)c1ccc(C)o1 +Cc1ccc(-c2n[nH]cc2CN2CC(C)OCC2c2ccccc2)o1 +CNC(=O)c1cnc(C=Cc2ccn(-c3ccccc3)n2)s1 +CCCn1nc(C(=O)N2CCC(OC)CC2)c2ccccc2c1=O +CC(C)(C)C(=O)N1CCCN(C(=O)c2[nH]nc3c2CCCC3)CC1 +COc1ccc(F)c(NC(=O)NCCNC(=O)c2ccc(C)cc2)c1 +Cc1cc(C(=O)OCC2CNC(=O)C2)c(C)n1C1CC1 +COc1ccc(S(=O)(=O)CC(=O)Nc2ccc(F)cc2)cc1 +CC(=O)NCCCSc1nnc(N2CCCCC2)n1C1CC1 +O=C(OCCOc1ccccc1Cl)c1ccc(-n2cnnn2)cc1 +O=C(Nc1ccc(-n2ncc3c(=O)[nH]cnc32)cc1)c1ccncc1 +CCN(CCO)C(=O)Cn1c(C2CCCCC2)nc2ccccc21 +CCc1cc(NCCc2nncn2C2CC2)nc(-c2ccncc2)n1 +Cc1nc2c(C#N)cnn2c(C)c1CCC(=O)NC1CCCCC1C +O=C1COc2ccc(NC(=O)N3CCc4cc(F)ccc4C3)cc2N1 +CCc1ncc2c(n1)CN(C(=O)Cc1ccc3[nH]c(C)nc3c1)C2 +CCc1nnc(NC(=O)N2CCOC(Cc3ccccc3)C2)s1 +Cc1cc2c(c(N)nn2CCO)c(=O)n1C1CCCCC1 +CCCc1noc(CCC(=O)N2CCCC2c2cccs2)n1 +Cc1ccc(CC(=O)NCc2ccc(OC(C)C)cc2)cn1 +O=C(NCc1cccs1)c1nnc(C(=O)Nc2ccccc2)s1 +CCc1ccccc1NC(=O)Cn1nc(C)cc1C +CCOC(=O)CN(CC)C(=O)c1cccc(F)c1 +COc1ccc(C2(C(=O)N3CCCN(C(N)=O)CC3)CCCC2)cc1 +CCN(CC(C)C#N)S(=O)(=O)c1ccc(C(N)=O)cc1 +CC1CC1C(=O)Oc1cccc(NC(=O)C2CC2)c1 +O=C(Nc1nc[nH]n1)c1cccc(NC(=O)c2cccs2)c1 +OCC1(O)CCN(c2nccc(C3CCCC3)n2)CC1 +CCOc1ccccc1CNC(=O)c1ccc(-c2ccccc2)[nH]c1=O +CC(=O)c1ccc(NS(=O)(=O)c2ccc(C)c(C)c2)cc1 +N#Cc1cc(COc2nnc(-c3ccccc3)o2)ccc1F +CCOC(=O)CN(C1CC1)S(=O)(=O)c1ccc(F)c(F)c1F +O=C(NCC#Cc1ccc(F)cc1)c1cc(-c2ccco2)on1 +CC(C)CN(C)C(=O)c1cc2c(nc3sccn32)s1 +CC(NC(=O)N1CCN(c2nccs2)CC1)c1cccnc1 +Cc1cccc(NC(=O)c2cc3ccccc3n2C)n1 +CCC(=O)Nc1cccc(NC(=O)c2ccc(F)cc2)c1C +CCc1n[nH]c(C2CN(C(=O)CCc3ccncc3)CCO2)n1 +CC1CN(C(=O)c2scnc2C2CC2)c2ccc(F)cc2O1 +COc1cc(OC)nc(CSc2ccc(N)cc2)n1 +CC(Sc1nnc(-c2ccccc2)o1)C(=O)NC1CCCC1 +CC(OC(=O)C1CCN(C(=O)N(C)C)CC1)C1CCCCC1 +CCn1cnnc1CNC(=O)Nc1cc(C)cc2cccnc12 +CCC(C)(C)NC(=O)C(C)S(=O)(=O)c1ccccc1F +COCCC(=O)NCc1ccc2[nH]c(-c3ccc(F)cc3)c(C)c2c1 +Cc1csc(CNc2cnn(-c3ccccc3)c2)n1 +O=C(CCCC1CCCCC1)N1CCN(C(=O)c2ccco2)CC1 +Cc1c(C(=O)N2CCOCC23CCC3)cnn1-c1ccncc1 +COc1cc(CNC(=O)C2CC(=O)Nc3ccccc32)ccn1 +COCc1ccc(CNC(=O)N2CCC(C)CC2C)cc1 +Cc1nnsc1C(=O)N1CCC(Cn2cnc3ccccc32)CC1 +CCOCCNC(=O)NCc1ccccc1CC +CNC(=O)NCC(=O)Nc1ccccc1C(=O)N1CC(C)CC(C)C1 +CSc1cccc(-c2ncc(F)c(NCCO)n2)c1 +O=C(c1cc(N2CCCC2=O)ccc1Cl)N1CC2CCCC2C1 +Cc1ccc(C(C)NC(=O)c2cc(S(N)(=O)=O)oc2C)cc1F +Cc1ccc(C)n1CCCCCn1c(C)ccc1C +O=C(NCCCn1ccc2cccnc21)c1ccc2ncsc2c1 +Cc1ccc(S(=O)(=O)c2nc(C)oc2N2CCC(C)CC2)cc1 +CCOC(=O)N1CCN(C(=O)c2cc(C)nc3ccc(C)cc23)CC1 +O=C(CSc1nnnn1-c1ccc(O)cc1)NCc1ccco1 +Cc1ccc(F)c(S(=O)(=O)NCc2cccc(C(N)=O)c2)c1 +Cc1ccc(-n2nc(CC#N)cc2C)cc1Br +Cc1ccccc1NC(=O)CSc1nnc(Cn2nccc2C)o1 +O=C(NC1CC1)c1ccc(N2CCN(c3ccccc3O)CC2)nc1 +CCc1nc2n(n1)CCCC2NC(=O)CN(C)c1ccccc1 +CCNS(=O)(=O)c1ccc(C)c(C(=O)N(C)Cc2ccccc2)c1 +CC(Oc1cccc(C#N)c1)C(=O)NCc1cn(-c2ccccc2)nn1 +CC(C)CC(=O)NCc1ccc(-n2ccnc2)c(F)c1 +O=C(CNC(=O)Cc1ccccc1)NCc1cccnc1 +CC(Cc1ccc(O)cc1)NC(=O)NCc1nc(C2CC2)no1 +CCCNC(=O)c1cc(-c2ccc(OC)cc2)n(CC)n1 +CC(=O)NC(C)(C)c1noc(-c2cnc(-c3cccs3)s2)n1 +O=C1CCc2cc(NCc3ccc(Oc4cnccn4)cc3)ccc2N1 +Cc1noc(C)c1C(C)NC(=O)NCc1cccnc1-n1cccn1 +CC(C)C(C)NC(=O)Nc1ccc(Cl)c(S(=O)(=O)N(C)C)c1 +CCOC(=O)C1(NC(=O)C2CCC2)CCCCC1 +Cc1ccc(SCCNS(C)(=O)=O)cc1C +CC(=O)N1CCC(NC(=O)CNc2cccc(Cl)c2Cl)CC1 +Cc1cc(Br)ccc1NC(=O)CCCN1CCOC1=O +CCCNC(=O)CNC(=O)NC(C)c1cccc(Br)c1 +Cc1csc(CN2CCCC(CNS(N)(=O)=O)C2)n1 +Cc1nn(C(=O)c2ccncc2)c2nc3ccccc3nc12 +N#Cc1ccc(C(=O)NCc2ccc3c(c2)OCO3)cc1 +CC#CCSc1nnc(-c2cncc(Br)c2)n1N +CCCc1ccc(C(=O)NCCOc2cccnc2)cc1 +CN(C(=O)CN1CCOCC1C1CC1)C1CCCCC1 +O=C(NCc1ccccc1-n1ccnc1)c1cc2ccccc2o1 +Cn1cccc1C(=O)N1CCOCC1c1nccc(NCC2CC2)n1 +O=C(OCc1ccco1)c1cc2cc(Br)ccc2oc1=O +CCCn1ncc2c(C(=O)Nc3cc(C)nn3C)cc(C3CC3)nc21 +COc1ccc(NC(=O)NC2CC2)c2cccnc12 +COc1ccc(CNC(=O)c2ccc(N)cc2)cc1 +CC(NC(=O)NC1CCN(S(C)(=O)=O)CC1)c1cccc(F)c1 +O=C(NCC(O)c1c(F)cccc1F)c1cc(Br)c[nH]1 +O=C(C1CC1)N1CCCC(OCc2cccc(F)c2)C1 +CNC(=O)CNC(=O)NC(C)COc1ccccc1C +CCOc1cc(-c2nc(C(C)=O)cs2)ccc1OC +Cc1cc(S(=O)(=O)NC2(C#N)CCOCC2)ccc1F +N#Cc1ccc(Sc2nnc3n2CCCCC3)nc1 +Cc1ccc2onc(CNC(=O)Nc3cccnc3)c2c1 +CCC(NC(=O)c1cccc(OC(C)C)c1)c1ccccc1 +COc1ccc(C(=O)N2CCN(c3ccc(F)cc3)CC2)c(O)c1 +CC(C)Oc1ccc(C(=O)NCc2nnc3n2CCCCC3)cn1 +Cc1cc(C(N)=O)nc(C2(C)CCCN2C(=O)c2ccccc2)n1 +C=CCOc1ccc(-n2ccnc2-c2cccnc2)cc1CO +CC(C(=O)Nc1ccc(S(=O)(=O)N(C)C)cc1)c1ccccc1 +COC(=O)C(C)n1c(C(F)(F)F)nc2cccnc21 +Cc1noc2nc(-c3cccs3)cc(C(=O)OC3CCOC3=O)c12 +COc1nc(C)ccc1CNc1cc(N2CCCC2CO)ncn1 +CC(=O)N1CC2CCC(C1)N(C(=O)c1ccccc1Cl)C2 +O=C(C1CC=CC1)N1CCC(c2c[nH]c3ncccc23)CC1 +Cc1nn(C(=O)Nc2ccc3c(c2)OCCO3)c2ccccc12 +Cc1c(O)ccc2c(CN(C)CCOCC3CC3)cc(=O)oc12 +Cc1nn(C)c(C)c1C(=O)Nc1ccc(Br)cc1Cl +CCc1cc(C(O)C2CCCO2)cc2c1NC(=O)C2C +O=c1c2ccccc2cnn1Cc1coc(-c2cccs2)n1 +CC(=O)c1ccc(NC(=O)COC(=O)c2ccc(O)cc2)cc1 +Cc1cc(C)n(-c2ccc(CNC(=O)C3CCCC3)cn2)n1 +C=CCc1cc(CN2CCOC(C)(C)C2)cc(OC)c1O +COc1ccc(CN(C)C(=O)NCCC(=O)N(C)C)cc1 +Cc1cccc(Cn2c(C3CC(=O)N(C4CC4)C3)nc3ccccc32)c1 +CCN(C(=O)Nc1ccc(-c2cc[nH]n2)cc1)C(C)c1cccnc1 +CC(C)(O)CN1CCN(C(=O)c2ccc(OC(F)(F)F)cc2)CC1 +CC(=O)c1cc(N)c2oc(-c3cccc(F)c3)nc2c1 +COc1cccc(C(=O)NC(C)CC(C)C)c1F +Fc1cc(F)cc(Cc2nc3nccc(-c4ccncc4)n3n2)c1 +CCCC(=O)Nc1cccc(NC(=O)c2c(OC)cccc2OC)c1 +N#Cc1ccc(C(=O)NC2CCCN(c3cccc(F)c3)C2)cc1 +COc1cccc(-n2ccnc2SCc2ccccn2)c1 +CC(=O)NCCCSc1nnc(OC(C)C)s1 +Cc1cc(C(=O)NCc2cn(C)nc2-c2ccccc2)cc(=O)[nH]1 +CCOc1ccc(-c2n[nH]cc2-c2ccc(OC)c(OC)c2)c(O)c1 +CCCNC(=O)Nc1ccc(C(C)N2CCOCC2)cc1 +COc1c(F)cc(NC(=O)c2cc(C(N)=O)cs2)cc1F +COc1cc2nc3noc(N)c3cc2c(OC)c1OC +O=S(=O)(c1ccc2c(c1)OCO2)N1CCOC2CCCCC21 +CCOC(=O)C1(NC(=O)c2ccc3c(c2)CCO3)CCCC1 +CNC(=O)C1CCC(=O)N(c2ccc(C)cc2)C1c1cccs1 +Cc1noc(C)c1CN(C)C(=O)c1cnn(-c2ccncc2)c1C +CCc1c(C(=O)Nc2cccc3cn[nH]c23)cnn1-c1ccccn1 +COc1ccc(C(=O)C(C)Sc2nc(C)c(C)o2)cc1OC +CCCn1c(C)nnc1SCc1csc(CC(=O)NC)n1 +Cc1cc2c(o1)CC(C)(C)CC2NC(=O)N(C)Cc1ccccn1 +Cc1cccn2c(=O)c3cc(C(=O)Nc4ccccn4)sc3nc12 +COC(CNC(=O)N1CCN(C(=O)C(C)(C)C)CC1)c1ccccc1 +COc1ccccc1CNC(=O)NCC(c1cccs1)N(C)C +O=C(c1cccc(-n2cccc2)c1)N1CCCC2(C1)OCCO2 +CCN(CC)S(=O)(=O)NC(C)c1ccc2c(c1)CCC(=O)N2 +O=C(Cn1cnc2ccccc2c1=O)NCc1cccc2ccccc12 +CN(CC(=O)NCC1(c2ccc(F)cc2)CCC1)S(C)(=O)=O +CC(C)NC(=O)CSc1ncnc2sc3c(c12)CCCC3 +Cn1c(=O)oc2cc(NC(=O)Nc3ccccn3)ccc21 +CN(Cc1cnn(C)c1)C(=O)Nc1ccc(-n2cncn2)nc1 +O=C(NCCc1ccccc1)NCC1CCN(c2ncccn2)CC1 +O=C(Nc1ccc(Cl)cn1)c1ccc(OCC2CCCO2)cc1 +O=C(Cc1c(F)cccc1F)NCCNC(=O)c1ccccc1O +C=CCOc1ccc(C(=O)N2CCCC(n3nc(C)nc3C)C2)cc1 +CCCn1nnnc1CN1CCC(Oc2ccc(C#N)cc2)CC1 +CCc1ccc(-c2ccc(C(C)(C)O)c(=O)n2C)cc1 +COc1ccccc1-c1n[nH]c(C2CC2)c1NC(=O)Cc1ccccc1 +CC(C)Cn1nccc1NC(=O)NCc1ccccc1 +Nc1c(-c2ccco2)nc2scc(-c3ccccn3)n12 +CC(=O)c1cccc(NS(=O)(=O)CC23CCC(CC2=O)C3(C)C)c1 +O=S(=O)(c1ccc(F)cc1)N1CCc2sccc2C1 +CCCn1cc(NC(=O)NCc2snnc2C(C)C)nn1 +Cc1noc(CCC(=O)NCCc2ccccc2F)n1 +CCOC(CC)C(=O)NC1CC1c1cccc(Cl)c1 +Nc1cnoc1Cc1ccc(Br)cc1 +CC(C)(C)OC(=O)N1CCC2CC(O)CCC2C1 +C=CCNC(=O)NCCc1coc(-c2ccc(F)cc2)n1 +CCC(Cn1ncc2ccccc2c1=O)NC(=O)Cc1ccsc1 +CSc1nc(N)nc(SCC(=O)C(C)(C)C)c1C#N +O=C(CS(=O)(=O)c1ccc2c(c1)OCCO2)NC1CCCC1 +CS(=O)(=O)N1CCCCC1C(=O)Nc1ccccc1C#N +COC1CN(C(C)C)CC1Nc1nc(C)nc2ccsc12 +CCS(=O)(=O)c1noc(C(=O)Nc2ncccn2)c1N +O=C(NCCc1ccc2c(c1)OCCO2)c1cccc(OC(F)F)c1 +CN(Cc1ccc2c(c1)OCO2)S(=O)(=O)N(C)C1CCCCC1 +COc1cc(Cc2nc(C(C)(C)NC(C)=O)no2)ccc1C +O=C(CCNc1ccccc1)Nc1cccc(F)c1F +C=C(C)COc1ccccc1C1Nc2ccccc2C(=O)N1C +CC(C)COc1ccc(NC(=O)NCc2ncn(C)n2)cn1 +COC1CCC2(CCN(C(=O)c3ccnnc3)CC2)c2ccccc21 +CCOc1ncccc1C(=O)N1CCN(C(=O)N(C)C)CC1 +Cn1ccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2)n1 +COc1ccc2nc(-c3ccc(C)c(NC(=O)C4CC4)c3)cn2n1 +CCC(C)(C#N)NC(=O)CCN(Cc1ccccc1)C(C)=O +Cc1noc(-c2ccc(C(=O)NC(C)CO)cc2)n1 +COC(=O)C1(NC(=O)Cn2cncn2)CCCCCC1 +CCCOc1cccc(C(C#N)NCc2cccnc2)c1 +CC(NC(=O)c1ccco1)C(=O)OCC(=O)N1CCCCCC1 +O=C(NCc1ccccc1F)C1COCC(=O)N1Cc1cccs1 +CC1Oc2ccc(S(N)(=O)=O)cc2N(C)C1=O +Cc1ccc2c(NC(=O)Cc3ccccc3)cccc2n1 +COc1ccc2c(ccn2CC(=O)Oc2cccc(C(C)=O)c2)c1 +CCCCNC(=O)CNC(=O)c1cccc(OC)c1 +CCn1nc(NC(=O)Cn2ccc(-c3ccccn3)n2)c2ccccc21 +CC(C)n1ccc(-c2nnc(NC(=O)c3ccn(C)n3)o2)n1 +COc1cc(C)c(NC(=O)NC2CCc3cc(F)ccc32)cc1OC +Cc1cccc(OC(C)C(=O)NCC(=O)N(C)C)c1C +CN(C)c1cc(N2CCCC(NC(=O)Cc3ccccc3)C2)ncn1 +CC(C)NC(=O)C1CCC(=O)N(C)C1c1ccc(F)cc1 +CC(=O)c1ccc(C#CCNC(=O)c2cc(-c3cccs3)n[nH]2)cc1 +COc1ccc(C(=O)NCCCn2ncccc2=O)cc1OC +CN(C)C(=O)CCCCSc1nccn1-c1cccc(F)c1 +CC(C)(C)n1nnnc1SCC(=O)NC1CC1 +CCC(=O)N(c1nnc(SCc2c(C)noc2C)s1)C1CC1 +C=CCc1ccccc1OCC#CCNC(=O)c1cccnc1OC +CCCCCn1nnc(CO)c1-c1ccccc1F +c1cc2c(cc1-c1nnc(C3CCCC3)o1)CCN2 +Cc1nc(CN(C2CC2)S(=O)(=O)c2cccnc2)cs1 +O=C(CCc1cccs1)N1CCC(C(=O)N2CCOCC2)CC1 +COc1ccsc1C(=O)N1CCC(OCc2ccc(F)cc2)CC1 +O=C(NCc1cccs1)C1CCC(=O)N1C1CCCCC1 +CCCNC(=O)CN(C)S(=O)(=O)c1c(C)cc(C)cc1C +CCC(OC)C(=O)Oc1cc(OC)ccc1C(N)=O +O=C(NCC(F)(F)F)C1CCN(C(=O)Nc2ccccc2)CC1 +CC(C)c1ccc(C2CCCN2C(=O)CCCn2cncn2)cc1 +CSc1nc2n(n1)CC(C(=O)N1CCN(C)CC1)=C(C)N2 +CCN(Cc1nc2ccccc2c(=O)[nH]1)C(=O)C1CCCO1 +O=C(CCc1cc2ccccc2o1)N1CCN(c2cnccn2)CC1 +COc1cc(Br)ccc1S(C)(=O)=O +CN(C)c1ccc(C(=O)N2CCOCC2(C)C)cn1 +O=C(Nc1ccc2c(c1)CCO2)c1cccc(NC(=O)c2ccco2)c1 +O=C(COC(=O)c1ccsc1)NCC1CCCO1 +C=CCNC(=O)C(NS(=O)(=O)c1ccc2ccccc2c1)C(C)C +COc1cccc(-c2cc(CNc3nnc(C)o3)on2)c1 +Oc1cccc(CC2NCCc3ccc(O)c(F)c32)c1 +O=C(NCc1ccccn1)c1ccc(Br)cc1F +COc1cc(C(=O)OCC#N)ccc1OCc1c(C)noc1C +CN(C)S(=O)(=O)Oc1cccc2c1OC(C)(C)C2 +CS(=O)(=O)NC1CCN(C(=O)c2ccc(F)cc2)CC1 +CCS(=O)(=O)N1CCOC2C(OCC3CC3)CCC21 +Cc1nn(C)cc1S(=O)(=O)N(Cc1ccncc1)C1CC1 +COC(=O)c1c(C)[nH]c(C(=O)NCCC(=O)Nc2ccccn2)c1C +O=C(CCCn1c(=O)oc2ccccc21)NC1CCCCNC1=O +Fc1ccc(NCCCN2CCOCC2)c(F)c1F +O=C(Cc1cn2ccccc2n1)N1CCCC1Cn1cccn1 +N#CCSc1nccn1Cc1ccc(Cl)cc1 +CC(C)c1nnc(NC(=O)NC(C)C(O)c2ccc(F)cc2)s1 +c1ccc(Nc2nc3ccccc3n3cnnc23)cc1 +CC(=O)c1ccc(S(=O)(=O)N2CCCn3ncnc32)cc1 +Cc1ccc(NC(=O)c2cn(C)c3c(Cl)cccc3c2=O)cc1 +COc1ccc(CCNC(=O)c2cc(C)n(C(C)C)c2C)cc1 +COCc1cc(NCc2ccncc2)n2nccc2n1 +CC(C)CCNC(=O)C(N)c1ccc(O)c(F)c1 +CCC1C(=O)NCCN1C(=O)C(C)c1cccs1 +Cc1cccc(NC(=O)C(C)Sc2ccccc2)n1 +CCc1ncnc(N2CCN(C(=O)c3ccc(=O)[nH]c3)CC2)c1F +COc1ccc(CCC(=O)Nc2cccc(NC(C)=O)c2)cc1OC +CCNC(=O)c1ccc(N(C)CC(=O)Nc2cc(F)cc(F)c2)nc1 +CC(c1cccc(O)c1)N(C)Cc1cc(C#N)cs1 +CN(C)C(=O)CCCC(=O)NCC(C)(C)c1ccc2c(c1)OCO2 +CC1CN(Cc2nnnn2Cc2ccccc2)CC(C)O1 +O=C(Cn1cnnn1)NCc1cc(F)ccc1Br +O=C(NCC1(O)CCOCC1)Nc1ccc(F)cc1 +O=C(Nc1ccc(F)c(NC(=O)C2CC2)c1)Nc1ccccc1F +CCCS(=O)(=O)N(C)CC(=O)Nc1cc(Cl)ccc1OC +Cc1csc(COc2ccccc2OCC(F)(F)F)n1 +Cc1nn2c3c(cnc2c1-c1ccc(F)cc1)CCC3 +CN(C)C(=O)N1CCCC(C(=O)Nc2ccc(F)c(Cl)c2)C1 +COC(=O)CN(Cc1ccccc1Cl)C(=O)c1ccc[nH]c1=O +CC(=O)Nc1cccc(NC(=O)CNC(=O)c2cc(F)cc(F)c2)c1 +COc1cc2c(c(OC)c1OC)C(=O)NCC2C1CCCC1 +CCOc1ccc2c(c1OCC)C(c1ccncc1)NCC2 +CNC(=O)Cc1ccc(NC(=O)c2cc(C)on2)cc1 +Cc1nc(N)cc(-c2ccc3c(c2)CC(=O)N3C)n1 +COCCNC(=O)CNS(=O)(=O)c1ccccc1 +C=CCNC(=O)Nc1ccc(CN2CCCC2=O)cc1 +CC(=O)c1cccc(-n2nnnc2SCC(N)=O)c1 +CCCCCCn1c(CO)nc2cc(OC)ccc21 +CN(CC1CCCC1)C(=O)Nc1nnc(C2CC2)s1 +CCn1ccnc1N1CCN(C(=O)c2ccccc2F)CC1 +COc1ccc2c(c1)C(NC(C)=O)C(=O)N2CCc1ccccc1 +CCCN(Cc1cc2ccccc2[nH]c1=O)C(=O)C1CCCCC1 +Cc1cc2c(s1)c1cnn(CC(=O)N(C)C)c(=O)c1n2C +CC(NC(N)=O)C(=O)Nc1ccc(OCC#N)cc1 +CC(=O)N1CCc2c1ccc(Br)c2O +COC(=O)C(C)CNC(=O)Nc1cccc(F)c1F +CCOC(=O)c1c(C)n(CCO)c2c1cc(O)c1ccccc12 +Cn1cc(CN2CC3OCC(C(=O)N4CCOCC4)C3C2)cn1 +N#Cc1ccc(NC(=O)COC(=O)CCc2c[nH]c3ccccc23)cc1 +CC(C)c1cc(C(=O)NC2(C)Cc3ccccc3C2)nn1C +CCn1cc(Br)c(C(=O)NC(C)C2CCCO2)n1 +CC(CO)NS(=O)(=O)c1ccc(C(C)(C)C)cc1 +COCC1COCCC12CCN(S(C)(=O)=O)CC2 +Cc1ccnc(NCC(c2ccc(C)s2)N2CCOCC2)n1 +C#CCN1CCN(C(=O)NCC2(c3cccc(F)c3)CC2)CC1 +COc1cc(C(=O)NC2CCC(C)CC2)ccc1OCC(N)=O +CCc1nnc(SCC(=O)Nc2ccc(F)cc2)o1 +CC(NC(=O)Nc1ccccc1)C(=O)Nc1ccc(F)cc1 +COCCOC(=O)c1cc2c(s1)CCC(C)C2 +C#CCOCC1CCCN(C(=O)c2cc(Cl)ccc2OC)C1 +Cc1ccc(C(=O)NCC(=O)OC2CCOC2=O)cc1 +CCn1c(SCC(=O)NC2CCCC2)nnc1-c1ccncc1 +CCOc1c(Cl)cc(CNC(=O)CC(C)C)cc1OC +CC1CCC(C)N(C(=O)Nc2ccc(OCC(=O)N(C)C)cc2)C1 +CCOc1ccccc1OC(=O)CCc1nc(C)no1 +CC(Oc1ccc(Cl)cc1Cl)C(=O)NCCCn1cncn1 +Cc1nn(C)c(C)c1CCC(=O)Nc1ccn(CC#N)n1 +Cc1n[nH]cc1CNc1cc(S(N)(=O)=O)ccc1Cl +COc1ccc(CC2CCCN2C(=O)c2cnn(C(C)(C)C)c2)cc1 +Cc1cc(S(=O)(=O)N2CCOCC2C2CC2)c(C)s1 +COC(=O)C(C)NS(=O)(=O)c1ccc(Cl)cc1C +Cc1cc2occ(CC(=O)N(CCO)Cc3ccccc3)c2cc1C +Cc1cc(C)c2c(c1)C(N)C(CN1CCOCC1)C(C)(C)O2 +COc1ccc(N2CCN(CC(=O)NCCCO)C2=O)cc1 +CC(C)c1nc2ccccc2n1CC(=O)Nc1ccc2c(c1)OCO2 +CC(C)OC(=O)c1cc(-c2cc(Cl)ccc2O)nn1C +CC1CCCCC1NC(=O)COc1ccccc1NC(=O)C1CC1 +Cc1ccc(NC(=O)C2CCN(S(=O)(=O)N(C)C)CC2)cc1C +CCCOc1cccc(NC(=O)N2CCC(n3cncn3)CC2)c1 +CC(CNC(=O)NC1CCCCC1CO)c1cccs1 +Cc1cc(C)n(Cc2ccc(C(=O)OCC(N)=O)cc2)n1 +Cc1cc(F)ccc1CCNC(=O)C1CC(=O)N(CC(F)(F)F)C1 +COc1cc(NCc2cc(CC(C)C)on2)ncn1 +NC(=O)c1ccc(NCc2ccn(-c3c(F)cccc3F)n2)cc1F +Cc1n[nH]cc1NC(=O)c1ccc(O)c(Cl)c1 +O=C(C1CC=CCC1)N1CCn2cc(C(F)(F)F)nc2C1 +CC(C)C(=O)Nc1ccccc1S(=O)(=O)NC(C)(C)C +CCCCC(=O)OCCn1c(=O)oc2ccccc21 +O=S(=O)(NCc1ccc2c(c1)OCO2)c1ccc(F)c(Cl)c1 +CS(=O)(=O)N1CCCC(Cc2ccc(-c3ccccc3)nn2)CC1 +C#Cc1cccc(NC(=O)CN(C)C(=O)Cn2ccc(=O)[nH]c2=O)c1 +COc1cccc(N2Cc3nc(=O)n(CCC(C)C)n3C2=O)c1 +CCOCCC(=O)N(C)Cc1cc(Br)cn1C +CSc1ccc(C(=O)N(Cc2cccs2)C2CC2)cc1 +COC1CCCCC1OC(=O)C1CCCN(C(N)=O)C1 +CS(=O)(=O)N1CCN(C(=O)Cc2ccc(Cl)cc2)CC1 +CCOC(=O)c1cc2sccc2n1CC(=O)N1CCOCC1 +CCn1ccc2ccc(NC(=O)NC(C)C3CCOCC3)cc21 +O=C(NCCCOCC(F)(F)F)c1cc(Br)c[nH]1 +O=C(c1cccnc1)N1CCn2nnc(COc3cccnc3)c2C1 +O=C(c1cccc(F)c1)N1CCN(C(=O)c2cc(Cl)c[nH]2)CC1 +O=C(Nc1ccc(-n2ccnc2)cc1)c1ccccc1 +Fc1ccc(CN2CCC(CN3CCOCC3)C2)c(F)c1 +OCCCc1nnc(-c2cc(Cl)cc(Cl)c2)o1 +Cc1cc2c(cc1N)CN(C)S(=O)(=O)C21CCCCC1 +Cc1ccc(SC(C)C(=O)N(C)CC(=O)NC2CC2)c(C)c1 +O=C(NCc1ccc(F)cc1)c1cnn(-c2ccc(F)cc2)n1 +C#CCNc1cccc(NC(=O)c2ccccc2)c1C +CN(CC(=O)NCc1ncc(-c2ccccc2)[nH]1)C(=O)c1ccccc1 +Cc1cc(Cl)ccc1S(=O)(=O)N(C)c1ccccn1 +CCc1ncc(CNCc2cccnc2Oc2ccccc2F)cn1 +Cc1nc(CNC(=O)c2cc(C(C)C)nc3onc(C)c23)c(C)s1 +CC(Oc1cccc(F)c1)C(=O)N1CCC(C(N)=O)c2ccccc21 +CCc1ncc2c(n1)CN(C(=O)C(C)Cn1cncn1)C2 +Cc1cccc(C)c1NC(=O)c1ccc(F)c(N)c1 +Cc1cccc(Cc2n[nH]c(CC(=O)Nc3cc(F)cc(F)c3)n2)c1 +N#CCOc1cccc(CC(=O)N2CCCC2Cc2ccccc2)c1 +CC(NC(N)=O)C(=O)N1CCN(CCOc2ccccc2)CC1 +CC(C)c1ccc(CCC(=O)Nc2ncc(C(N)=O)s2)cc1 +Cc1ccc(NS(=O)(=O)Cc2ccc(F)cc2)cc1 +O=C(NCC#Cc1ccc(N2CCNC2=O)cc1)c1ccncc1 +COc1ccccc1C(O)Cn1cc(C(=O)NCc2ccco2)nn1 +Cc1nc(CN2CCN(C(=O)c3cc(C4CC4)[nH]n3)CC2)cs1 +COc1ccc(CC(=O)N(C(C)C)C2CCOCC2)cc1 +CCCn1c(C)nnc1SCc1nsc(N(C)C)n1 +COc1cc(=O)n(CCOc2ccccc2C#N)cc1Br +COc1cc(NCCc2nc3ccccc3[nH]2)ncn1 +Cc1noc(C)c1C(C)NC(=O)c1ccn(-c2cccc(F)c2)n1 +CC(C)Cc1cc(C(=O)NCCN2c3ccccc3CC2C)[nH]n1 +COc1cc(C)ccc1OC(=O)c1cccc(CN2CCCC2=O)c1 +CC(NC(=O)C(NC(=O)Nc1ccccc1)C(C)C)c1ccncc1 +Cc1cnc(NC(=O)C2(c3ccc(Cl)cc3)CC2)s1 +CC(C)n1cnc(S(=O)(=O)N2CCCC(C(=O)NC3CC3)C2)c1 +Cc1nc(-c2cccc(NS(=O)(=O)c3cn(C)nc3C)c2)cs1 +CC(C)OCCCNC(=O)NC1COc2ccccc2C1 +O=c1ccc(C(F)(F)F)cn1Cc1cc(=O)n2ccsc2n1 +CCc1nnc(C(C)N2CCN(Cc3nccn3C(F)F)CC2)o1 +O=C(Cn1cc(C(F)(F)F)ccc1=O)c1ccc2c(c1)OCO2 +CNC(=O)c1cnc(C=Cc2ccc3c(c2)CCO3)[nH]c1=O +CCCc1nnc(NC(=O)Cc2coc3cc(C)ccc23)s1 +Cc1cnc(CCNC(=O)c2ccc(-n3cncn3)cc2)s1 +CC(C)(C)C(NC(=O)c1cc2cc(F)ccc2oc1=O)C(N)=O +COc1cc(C(C)=O)ccc1OCC(=O)Nc1ccccc1C +Cc1ccc(C(O)CCCC(=O)NCc2cccnc2)cc1 +CC(C)N(Cc1cccnc1)C(=O)c1cn(CC(=O)N(C)C)nn1 +Cc1cnc(CNC2CCc3c(F)ccc(Br)c32)s1 +CCOC(=O)Cc1csc(NC(=O)c2ccccc2F)n1 +CC(C)OCC(=O)N1CCN(C(=O)c2cccc3ccccc23)CC1 +CN(c1ccccc1F)S(=O)(=O)c1c[nH]c2nccc(Cl)c12 +CN(Cc1cccc(C#N)c1)C(=O)CNC(=O)c1ccccc1 +CCOC(=O)COC(=O)C1CC1c1ccccc1F +O=C(CNc1cccc(F)c1)N1CCc2ccccc21 +CC(C1CC1)N(C)C(=O)c1ccc(Br)cc1 +Cc1ccc(F)cc1C(=O)Nc1cccc(-n2cnnn2)c1 +CC(C)CNC(=O)NCc1ccc(Oc2cccc(F)c2)nc1 +NC(=O)Cc1ccc(NC(=O)NCc2ccc(Cl)cc2)cc1 +Cn1nc(C(=O)Nc2ccc(NC(=O)c3ccco3)cc2)ccc1=O +O=C(NCC(O)COc1ccc2c(c1)OCO2)c1ccc(Cl)cc1 +Cc1nc2cc(NC(=O)c3cn(C)c4ccccc34)ccc2o1 +Cc1nn(C)c(=O)n1-c1ccc(OCc2ccccc2)cc1 +CC(C)CCC(C)NS(=O)(=O)c1cccc(C(N)=O)c1 +O=C(NCCc1ccccc1Cl)c1ccc[nH]c1=O +Cc1cc(NC(=O)N2CCC(O)C2)c2ncccc2c1 +COCc1c(C(=O)NCCNC(C)=O)sc2cccc(F)c12 +CCOC(=O)C1CCCC(=O)N1c1cccc(C)c1C +COCCN(CC(C)C)C(=O)C1CC(=O)N(c2ccc(C)cc2)C1 +Cc1noc(C)c1C(C)C(=O)NC1CN(c2ccc(F)cc2)C1=O +CC1CCc2nc(CN(CCO)Cc3cccnc3)sc2C1 +Brc1ccc2c(c1)OCc1nncn1-2 +CC(C(=O)N(C)C1CCCN(c2ccccc2)C1=O)c1cccs1 +O=C(NCCc1ccccn1)C(c1cccnc1)N1CCCC1 +COc1ccc(CCC(=O)Nc2cc(-c3ccsc3)no2)cc1 +COc1ccc(CN(C)C(=O)COc2ccc(Cl)cc2)cc1 +Cc1cc(C)c(NC(=O)c2cc(N)c[nH]c2=O)c(Cl)c1 +CC(Nc1ccc2c(c1)n(C)c(=O)n2C)C(=O)N(C)CCC#N +CCc1nc(C(C)NC(=O)C(C)Cc2ccccc2F)cs1 +CCn1nccc1CNc1cc(Cl)cc2c1OCC2 +Cc1ccc2nc(C3CN(S(=O)(=O)c4ccccc4F)C3)[nH]c2c1 +CCC(O)C1CCCCN1S(=O)(=O)c1cc(C#N)ccc1C +Cc1nc(NC(=O)c2ccc3c(c2)CCC(=O)N3C)cc(C2CC2)n1 +CC1(CNC(=O)Nc2ccc3c(c2)NC(=O)CS3)CCCC1 +COc1ccc(F)cc1NC(=O)c1cnn(-c2ccc(Cl)cc2)c1 +CC(=O)c1ccccc1NC(=O)Cc1ccc(-n2cccc2)cc1 +Cc1noc(C)c1COc1ccc(CN2C(C)COCC2C)cc1 +Cn1c(SCCCN2CCOC2=O)nc2ccccc21 +CCN(Cc1ccoc1)S(=O)(=O)c1ccc(C)c(C(F)(F)F)c1 +O=C(Nc1nccs1)c1cc(Cl)c2c(c1)OCO2 +CCOC(=O)c1cc2c(OC)ccc(Br)c2[nH]1 +Cc1ccc(-n2cc3c(c(C#N)c2=O)CCCC3)cc1Cl +COc1cc(OC)cc(C(=O)Nc2ncn(Cc3ccccc3)n2)c1 +CCN(C(=O)c1ccc(NC)nn1)C1CCCCC1 +CC(Cc1ccccc1)c1n[nH]c2ncnc(N)c12 +Cc1cc(C)c(CNC(=O)CCc2cc3ccccc3o2)c(=O)[nH]1 +O=C(Nc1ccc(F)cc1F)c1cn2c3c(cccc3c1=O)CC2 +O=C(c1ccc(Oc2ccccc2)nc1)N1CCOCC1C1CC1 +Cc1cnc(C(=O)Nc2nnc(SCc3cccs3)s2)cn1 +CCOc1ccccc1C(=O)N1CCc2sccc2C1C(=O)OC +Cc1cc(S(=O)(=O)NCC2CCOCO2)c(Cl)cc1F +CNC(=O)c1ccc(CN(C)C(=O)c2cc3c(s2)CCCC3)cc1 +COc1cccc(NC(=O)c2cc3cccnc3n(C)c2=O)c1 +Cc1ccc(CS(=O)(=O)c2ccc(C(=O)C(C)C)cc2)cc1 +COc1ccc(-c2cc(N)nc(=O)[nH]2)cc1Cl +O=C(NCCc1c(F)cccc1F)C1CCCN1c1nccs1 +CC(=O)Nc1cc(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)ccc1C +Cc1n[nH]cc1CNS(=O)(=O)N1CCC(C)CC1 +COc1ccc2cc(CCNC(=O)c3ccccc3C)c(=O)[nH]c2c1 +C=C(C)CSc1nnc(-c2ccccc2OC)n1N +COCCN(CC(C)C)C(=O)c1cccc(OC)c1 +CC1CCCCN1C(=O)COC(=O)c1cccn1C +CCn1cc(Br)cc1C(=O)Nc1cc(F)ccc1N +Cn1ncc(C(=O)N2CCOc3ncccc32)c1C(F)F +O=C(c1sccc1-n1cnnn1)N1CCN2CCCCC2C1 +Cc1cc(CSc2nncn2-c2ccc(C)c(Cl)c2)no1 +C=CCOC(C)C(=O)NC(C)c1ccc(C#N)cc1 +CC1CC1COC(=O)CCn1c(=O)oc2ccccc21 +COCc1cc(CNC(=O)c2ccc(C3CCCO3)s2)n[nH]1 +O=C(Cc1cccc2ccccc12)NCc1cn2ccccc2n1 +Cc1cccc(OCCN2CCCS2(=O)=O)c1 +CCCCS(=O)(=O)NCc1cccc(C(=O)NC)c1 +CC(Oc1cccc(F)c1)C(=O)Nc1ccccc1C#N +CCCCN(C)C(=O)CC(C#N)c1cccc(F)c1 +CCN(Cc1cccc(NCC(=O)N2CCCCC2C)c1)C(C)=O +COc1ccc(C(=O)N(C)CCc2ccccc2)nn1 +CC(C)c1ccccc1OCCCCN1CCOCC1 +O=C(NC1CCc2c(O)cccc21)c1cc(Br)c[nH]1 +O=C(NCCn1nc(-c2cccs2)oc1=O)c1ccco1 +Cc1nc(C)c(CC(=O)NC2(C)CCCC2)c(=O)[nH]1 +Cc1nn(C)c(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)c1C +Cc1cc(=O)c(OCC(=O)Nc2nc(-c3ccccn3)cs2)c[nH]1 +COc1ccccc1C(=O)NCCC(=O)N1CCN(C(C)=O)CC1 +Cc1cccc(C(=O)Nc2cnc3ccc(C)cn3c2=O)c1 +C=CCOC(C)C(=O)NCc1ccc(C(=O)NC)cc1 +CCOC(=O)c1ccn(-c2ccc(NC(=O)c3csnn3)cc2)n1 +COc1cccc(C(=O)Nc2cnn(Cc3ccccc3)c2)c1F +CC(C)c1c(C#N)nnn1CCCc1ccccc1 +C=CCN(Cc1cccc(C#N)c1)Cc1cncs1 +CCN(CC)C(=O)NCc1cc(Br)cs1 +CC(C)c1cccc(NC(=O)CSc2ncn[nH]2)c1 +CCN(CC)C(=O)CN(Cc1ccccc1)S(C)(=O)=O +Cn1nc(-c2cccs2)cc1C(=O)Nc1nncs1 +CCOc1cccc(C(=O)N2CCN(C3CCCC3O)CC2)c1 +CC1CCCC(NC(=O)Cn2cnc3c(cnn3C)c2=O)C1C +Cc1noc(CCNC(=O)C2(c3cccs3)CCCCC2)n1 +CCC(C)NC(=O)C1CCCN(c2nnc(-n3cccc3)s2)C1 +CC(O)CC(C)(C)CNC(=O)C1CCN(C(=O)C(C)(C)C)CC1 +CCC1CN(C(C)=O)CCC1NC(C)C(=O)NCc1cccs1 +Cc1nc(-c2ncccn2)sc1C(=O)OCc1nccs1 +O=C1CN(C(=O)Nc2cc(Cl)ccc2Cl)CCN1 +COc1ncccc1C(=O)N1CCOC(C)(C)C1 +CC(C)CCNC(=O)CSc1ccc(F)cc1 +COc1ccc(C(CC(=O)NCC2(C)COC2)c2ccccc2)cc1 +COc1cccc(C(O)CNc2cccc(NC(C)=O)c2)c1 +COC(=O)CNc1ccc(NC(C)=O)cc1C(F)(F)F +Cn1c(=O)n(C)c2cc(NC(=O)c3cccs3)ccc21 +CN(Cc1cc(Br)cs1)C(=O)c1n[nH]cc1N +Cc1nc(CCC(=O)c2ccc3c(c2)OCCO3)sc1C +CN(Cc1ccco1)C(=O)C1CC(=O)Nc2cc(F)ccc21 +COC(=O)CSc1ncnc2c1oc1nc(C)cc(C)c12 +CCc1ccccc1CNC(=O)NCC1CN2CCCCC2CO1 +CNC(=O)NCC1CCCC(CNC(=O)NC)C1 +CSc1ccc(CNC(=O)c2cnc(C)nc2C)cc1 +CC(C)n1nccc1NC(=O)CSc1nnnn1C1CCCCC1 +COc1cccc2c1OCC(NC(=O)N(CCCCO)C1CC1)C2 +N#Cc1ccc(NC2CCN(C(N)=O)CC2)cc1Cl +COCCn1c(-c2ccc(OC)cc2)ccc(C(C)=O)c1=O +Cc1cc(NC(=O)C(C)OC(=O)C23CC4CC(CC(O)(C4)C2)C3)on1 +OCc1ccc(C2NCCc3ccc(Cl)c(F)c32)cc1 +c1cnc(N2CCOC3CCC2C3OCc2cccnc2)nc1 +Cc1cc(C)n2nc(C(=O)Nc3cccc(-c4nc[nH]n4)c3)nc2n1 +CCCc1cc(N(C)Cc2nc(C)n[nH]2)n2ncnc2n1 +Cc1cccc(NC(=O)CNC(=O)CCC(C)C)c1C(N)=O +O=C(NCc1nn(Cc2ccccc2)c2ccccc12)c1ccccn1 +CCCC1CN(C(=O)CNC(=O)N2CCc3ccccc3C2)CCO1 +CC(=O)c1ccc(NC(=O)c2nn(C)c3c2COc2ccccc2-3)cc1 +CCCNC(=O)Nc1[nH]c(C)c(C(=O)OCC)c1C +NC(=O)c1ccc(NC(=O)Nc2cccc(Cl)c2Cl)cc1 +COc1cc2c(cc1OC)C(COc1ccccc1C)NCC2 +CC(=O)Nc1cccc(N2CCn3c(nc4ccccc43)C2)c1 +Cc1cc(C)n2c(CN3CCC(Nc4ccccc4)C3)cnc2n1 +Fc1ccc(C2NCCc3c(Cl)cccc32)nc1 +CC1CCCC(N(C)C(=O)CNS(=O)(=O)c2cn(C)cn2)C1 +O=C(NCCOc1ccccc1)c1cnc(C2CCCO2)s1 +CCCOc1ccc2c(c1)nc(CC#N)n2C(C)C +CC(Cc1ccsc1)NC(=O)c1ccc2c(c1)OCO2 +CC1CCCC(CNC(=O)CN(C)C(=O)C(C)n2cccn2)C1 +CN(C)C(=O)C1CCN(C(=O)C2CC2c2ccccc2F)CC1 +CCOc1ccc(C(=O)Nc2ccnn2C2CCCC2)cc1OC +COC(=O)c1sccc1NS(=O)(=O)N1CCNCC1 +O=S(=O)(CC1CCCO1)c1nnc(NCc2ccco2)s1 +CC(=O)c1c(C)[nH]c(C(=O)NCC(c2cccs2)N(C)C)c1C +CC(C)(CNC(=O)c1ccc(O)c(Cl)c1)c1ccncc1 +CCn1nccc1CNC(=O)c1cnc2sccn2c1=O +Cc1ccccc1CC(=O)Nc1ccc(S(C)(=O)=O)nc1 +Cc1noc(C)c1C(=O)NC(C)C(=O)NC(C)(C)C +CC1(C)Cc2nc3ncn(CCc4ccccc4)c(=O)c3cc2CO1 +CCn1cc(SCC(=O)Nc2nnc(C)s2)c2ccccc21 +CCC(=O)Nc1ccc(NC(=O)c2c(C)cc(C)[nH]c2=O)cc1 +O=C(CCN1C(=O)CCc2cc(F)ccc21)N1CCCCC1 +CCOc1ccccc1-c1noc(COc2cccnc2C)n1 +Cc1ccc(C(O)CN2CCN(c3ncccn3)CC2)cc1 +COc1ccc(CN2CC(C(=O)N3CCOC(C)C3)CC2=O)cc1 +Cc1ccc(OCC(=O)N2CCc3c(N)cccc3C2)cc1 +CN(C)S(=O)(=O)c1ccc(=O)n(Cc2ccc(C#N)cc2F)c1 +Cc1cc(N(C)C(=O)CS(=O)(=O)N(C)C)ccc1Br +CC(C)c1cc(C(=O)N=c2sccn2C)n[nH]1 +NC(=O)c1cnc(NC(=O)C2CCCCC2)s1 +CC(C)CNC(=O)N1CC2CC(C(=O)NCc3cccnc3)C(C1)O2 +COc1cccc2cc(C(=O)NCCC(O)c3cccs3)oc12 +Cc1ccccc1CNC(=O)COc1cccc(C#N)c1 +CC(=O)Nc1cccc(NC(=O)c2nccc3c(N)cccc23)c1 +Cc1ccccc1C(C)NC(=O)N1CCN(CC(=O)NC(C)C)CC1 +COCc1nc(-c2nc(-c3cc4ccccc4o3)no2)cs1 +Cn1cccc1C(=O)N1CCN(CC(=O)NCc2ccccc2)CC1 +CCn1nc(C)cc1NC(=O)c1c(F)cccc1Cl +CCc1ccc2occ(CC(=O)N3CCCC3COC)c2c1 +CCOc1ccc(F)c(C(=O)NC(C)Cc2ccc(O)cc2)c1F +COc1ccc(-c2n[nH]c(SC(C)C)n2)c(OC)c1 +Cc1ccc(C2CCCN2C(=O)c2cc(C)oc2C)cc1 +CCOC(=O)C1=C(C)N=C2Nc3ccccc3N2C1c1ccncc1 +O=C(c1ccccc1F)N1CCC(c2nc(-c3ccccc3)no2)C1 +COCCOc1ccc(CN(C)C2CCCc3nc(C)sc32)cc1 +COC(=O)c1cn(C2CCCCC2OC(=O)CC2C=CCC2)nn1 +Nc1ccccc1OCc1cccc(COc2ccccc2N)n1 +CCOc1cc(F)ccc1NC(=O)Cc1ccc(C)nc1 +Cc1ccccc1OCC(=O)Nc1cccc(N(C)S(C)(=O)=O)c1 +O=C(NCCS(=O)(=O)c1ccccc1)NCc1cscn1 +Cc1n[nH]c(=NC(=O)c2ccccc2Cl)n1C +CC(C)CN(CC(=O)NC(C)C)c1cccc(O)c1 +Cc1ccn(CC(=O)NCCOc2ccc(F)cc2)c(=O)c1 +COc1ccccc1CN(CCO)C(=O)Nc1cc(C)ccc1C +Cc1cc(C(=O)Nc2nnc(-c3ccc4c(c3)OCCO4)o2)c(C)o1 +Cc1ccc(-c2nnc(CCC(=O)N3CCCCC3C(N)=O)o2)cc1 +Cc1c(C(=O)NC(C)c2ccncc2)oc2c(F)cccc12 +Cc1nn(C)c(C)c1NC(=O)CN(CC(C)C)CC(F)(F)F +CN(CCO)C(=O)CCc1ccc(C(C)(C)C)cc1 +O=C1Cc2cc(NC(=O)c3c(F)cccc3Cl)ccc2N1 +Cc1cc(NC(=O)c2cccc(CSc3nccn3C)c2)[nH]n1 +O=C(c1ccsc1)N1CCCC2(CCN(c3cncnc3)C2=O)C1 +COc1ccccc1NC(=O)c1ccnc(OC2CCC2)c1 +CN(CC(=O)Nc1ccc(F)c(F)c1F)C(=O)CC1CCCC1 +Cc1cccnc1NC(=O)NC(C)(C)c1ccccc1 +C#CCNC(=O)CSc1ncc(C(F)(F)F)cc1Cl +CC(C)CC(NC(N)=O)C(=O)N(C)CCc1ccc(F)cc1 +CC(NC(=O)c1cn2cccnc2n1)c1ccc(C#N)cc1 +Cc1cc(C(=O)NC(C)(C)C(N)=O)c(C)n1Cc1ccccn1 +CCc1cc2c(=O)n(CCOc3ccccc3OC)cnc2s1 +Cc1ccc(CN2CC(C(=O)NC3(C#N)CCCCC3)CC2=O)cc1 +COCC(=O)N1CCC(c2onc3c2CC(C)CC3)CC1 +CC(C)CC(NC(=O)NC1CCOC(C2CC2)C1)c1ccccn1 +Cc1nc(SCC(=O)NCCc2ccccc2)oc1C +Cc1ccc(C(N)c2c(-c3ccccc3)cnn(C)c2=O)cc1 +Cc1cc2c(cc1C)N(CC(=O)N1CCOCC1)C(=O)CN2 +CC(=O)c1ccc(O)c(NC(=O)c2ccc(Oc3cccnc3)cc2)c1 +CC(C)Cc1noc(CN(C)Cc2nc3ccccc3c(=O)[nH]2)n1 +Cc1ccc(C)c(CC(=O)Nc2nc3ccc(F)cn3n2)c1 +O=C(Nc1ccccc1)C1CCCN1C(=O)c1cnc2ccoc2c1 +CCOc1ccc(S(=O)(=O)NC(C)CC)cc1C +Cc1cc(-c2cn(Cc3ccccc3)cc2N)n[nH]1 +CC(=O)Nc1cc(NC(=O)Nc2ccc(-c3cc[nH]n3)cc2)ccc1C +CCC(=O)Nc1ccc(NC(=O)c2cccc3c2ccn3C)cc1 +COC(=O)N(C)c1ccc(NC(=O)c2ccc(OC)c(F)c2)cc1 +CNc1snc(C)c1C(=O)Nc1ccc(-c2csnn2)cc1 +Cc1nccc(NC(=O)C2CN(Cc3ccccc3)CCO2)n1 +COCCCNc1ncnc(Oc2ccc(C)c(C)c2)c1N +Cc1cc(C(=O)CSc2nccn2C)c(C)n1Cc1ccccc1 +CSc1ncccc1C(=O)N(Cc1ccsc1)C1CC1 +CC1=NC(C(=O)N2CCCC(C(=O)NCc3ccco3)C2)C(C)=C1C +Cc1noc(C)c1C(C)NC(=O)c1ccc(F)cc1Cl +CCOc1cc(C(=O)Nc2nc(C)cs2)ccc1OC(F)F +Cc1cc(Cl)c(NC(=O)N(C)Cc2ccncc2)c2cccnc12 +COc1cc(C(=O)NCCC#N)cc(OC)c1OC +COc1ncccc1CNC(=O)c1ccc2c(c1)NC(=O)CCS2 +CCCNC(=O)c1ccc(F)cc1Br +CC1CN(C(=O)NC2CCCCNC2=O)CC(C)O1 +Cc1ccccc1OCCn1cnc2cc(F)ccc2c1=O +Cc1cccc(NC(=O)CN(c2cccc(C)c2)S(C)(=O)=O)c1 +O=C(NCCc1ccccc1)C(O)c1ccccc1Cl +Cc1noc(COC(=O)c2cc3cc(Cl)ccc3nc2C)n1 +CCN(C(=O)CCNS(C)(=O)=O)C(C)c1ccc(F)cc1 +CC(=O)N1CCN(CCN(CC2C(C)C=C(C)CC2C)C(C)=O)CC1 +COC(=O)C(O)(CC(=O)Nc1ccc(F)cc1C)C(F)(F)F +Nc1cc(N)nc(SCCOc2cccc(Br)c2)n1 +CCCc1nnc(NC(=O)c2cc(-c3csc(C)n3)cn2C)s1 +Cc1cc(NC(=O)c2ccc(N3CCCC3=O)cc2)no1 +O=C(C1CCOCC1)N1CCN(c2ncccn2)CC1 +CCCc1c(C(=O)OCC)cnc2nc(SC)nn12 +N#Cc1cccc(NC(=O)Cc2ccc(Br)cc2)c1 +COc1c(Cl)cc(Cl)cc1-c1coc(N)n1 +CCNC(=O)c1ccc(CNS(C)(=O)=O)cc1 +Cc1cc2ccccc2n1CCN(C)C(=O)CCc1ccncc1 +CCc1cccc(N2CCC(NC(=O)NCc3cnn(C)c3)CC2)c1 +O=C(Nc1cnn(Cc2ccccc2)c1)NC1CCCCC1 +O=C(NCc1ccc(-n2ccnc2)nc1)C1C2CC3CC(C2)CC1C3 +COc1ccccc1NC(=O)Cn1nccc1-c1ccncc1 +Cc1nc(N2CCOCC2)nc2c1CN(C(=O)c1ccno1)CC2 +CC(C)(C)OC(=O)NCc1cccc(NC(=O)c2ccccn2)c1 +Cn1c(C(=O)NCc2cccnc2)cc2c(Cl)cccc21 +COc1ccc(CC(C)CN(C)S(=O)(=O)C2CCOCC2)cc1 +Cn1cnnc1C1CCCN(C(=O)c2ccc(-n3ccnn3)cc2)C1 +CCc1ccc(S(=O)(=O)N2CCCC(C(N)=O)C2)s1 +CCOc1cc(C)c(Cl)cc1S(=O)(=O)NCc1ccncc1 +Cc1cccc(OCCCCC(=O)Nc2cc[nH]n2)c1 +CCOC(=O)c1nn(-c2ncccn2)c2c1CNCC2 +Cc1ccc(CC(=O)NCC(=O)N2CCCC2)cc1 +COc1ccc(Cc2nc3ccccc3n2CC(N)=O)cc1OC +COCc1nnc(SCCC(=O)Nc2cccc(Cl)c2)n1N +COC(=O)C(C)NC(=O)c1ccccc1NC(=O)c1ccsc1 +CC(Cn1cccn1)NC(=O)CSc1nccn1C +CCOC(=O)CCNC(=O)c1c(CC)noc1C +CC(C(=O)N1CCCN(c2ncccc2C#N)CC1)n1ccnc1 +CCc1cc(C#N)c(NC(=O)C2CCN(C(C)=O)CC2)s1 +O=C(NCCOc1cc(N2CCOCC2)ncn1)c1ccc(F)cc1 +CCc1nnc(NC(=O)N(C)CCCOc2ccccc2)s1 +Cc1ncc(CN(C)CCC(=O)OC(C)(C)C)s1 +CC1CN(CCC(=O)Nc2cccc(C#N)c2)CCO1 +CCOc1ccc(OCC)c(NCc2cccnc2)c1 +O=C(C1CC1c1ccccc1)N1CCCCC1c1nccs1 +O=C(c1cc[nH]n1)N(CCc1ccccc1)C1CCCC1 +CCNC(=O)COc1cccc(NC(=O)Nc2cccc(C)c2)c1 +CCc1nc(-c2ccc(CNC(C)=O)s2)cs1 +Cc1cccc(C2CCCN2C(=O)NCc2ncn(C)n2)n1 +CC(C)n1cc(Br)cc1C(=O)N(C)C1CCOCC1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)Nc3nc(C)cs3)ccc21 +Nc1cncc(-c2ncccc2C(=O)N2CCCC2)c1 +COc1ccc2c(c1)C=C(CNc1cccnc1)CO2 +CN(C(=O)CN(C)S(=O)(=O)c1ccc(F)cc1)C1CCCCC1 +CCCc1n[nH]c(SC(C)c2cn(-c3ccccc3)nn2)n1 +CC(C)NC(=O)NCC(=O)N1CCc2ccccc2C1 +O=C(NCc1ccncc1)c1cc(F)ccc1Br +CNC(=O)c1nc(-c2ccc(COc3c(C)occc3=O)cc2)no1 +CCCC(=O)N1CCCC(C(=O)N(C)Cc2cc(C)on2)C1 +CCn1c(=O)n(CC(=O)NCc2cscn2)c2ccccc21 +CCc1ccc2nc(C)cc(C(=O)N(C)Cc3nnc(CC)o3)c2c1 +CC(=O)N1CCN(C(=O)CS(=O)(=O)c2ccccc2C)CC1 +Cc1cc2c(cc1C)N(CC(=O)OC1CCCC1)C(=O)CN2 +NS(=O)(=O)CCSc1ccc(-c2ccccc2)cc1 +Brc1ccc2nc(-c3ccncc3)oc2c1 +CNC(=O)C1C(OC2CC2)=CC=NC1NS(C)(=O)=O +CCNC(=O)C1CC(=O)Nc2nc(N3C(C)CCCC3C)[nH]c(=O)c21 +CCCCCCN1CC2(CCN(C(=O)C3CCOC3)CC2)OC1=O +Nc1oc(-c2cccc(F)c2)cc1C(=O)c1ccco1 +CCCCN(CC(F)(F)F)C(=O)Cn1c(C)csc1=O +CCc1c(C)sc(NC(=O)c2ccccc2Cl)c1C(N)=O +Cc1ccc(C(C)OC(=O)CCC(=O)Nc2nccs2)cc1 +CCn1nc(C)cc1C(=O)N1CCCC1c1ccc(OC)cc1 +CCNC(=O)c1ccc(NC(=O)NC(CC)CCO)c(C)c1 +Cc1ccc(-c2ncco2)cc1NC(=O)C1CNC(=O)C1 +Cc1cc(=O)cc(C2CCCN2S(=O)(=O)c2cn[nH]c2)[nH]1 +CCCn1c(C)cc(=O)c(O)c1CN1CC(C)OC(C)C1 +Cc1nc(C(=O)N(C)CC(N)=O)nn1-c1ccc(F)cc1 +O=C(c1ccc[nH]c1=O)N1CCC(c2ccccc2)CC1 +CCc1ccc(C(C)NC(=O)c2ccc(S(C)=O)cc2)cc1 +COc1ccc(N(C)S(=O)(=O)c2cccc(Cl)c2)cn1 +CCOCCC(=O)Nc1ccc(C)c(S(N)(=O)=O)c1 +CCOC(=O)Nc1cc2c(cc1N)OCCCO2 +Cc1noc(C)c1CC(=O)N1CCCC1c1nc(C2CC2)no1 +Cc1nnc(SCCOc2ccccc2)n1-c1ccccc1 +Cc1cccc(S(=O)(=O)CC(=O)NCC2CC2)c1 +CCOC(=O)CN(CC)S(=O)(=O)c1ccc2c(c1)CCO2 +COCCOCC(=O)NCc1cc(Br)cs1 +CCCn1ncc(N2CCC(C(=O)NCCC(C)C)CC2)cc1=O +Cc1cc(NC(=O)c2ccc(S(=O)(=O)N(C)C3CC3)cc2)on1 +Cc1cc(C)nc(NC(=O)NCCCSc2ncccn2)n1 +Cc1cc(NC(=O)N(C)Cc2sccc2C)n(C)n1 +CC(=O)c1ccc(CNC(=O)Cc2ccc(F)cc2)nc1C +CCOC(=O)N1CCN(c2ccc(Cl)cc2N)CC1 +Cc1cccc(S(=O)(=O)N(C)C2(C#N)CCN(C)CC2)c1 +CCOC(=O)N1CCN(C(=O)c2ccc(OC)c(N)c2)CC1 +O=C(NC1CCCCC1)c1ccc(S(=O)(=O)N2CCCC2)o1 +COc1ccccc1Oc1ccccc1-n1nnnc1C +COCCC1(C(=O)N2CCC(O)(C(F)(F)F)CC2)CCC1 +Cc1ccc(-c2cc(NC(=O)CC(C)C)on2)cc1 +Cc1ccc(-n2nc(C(=O)N3CCCC(C)C3)c(=O)n(C)c2=O)cc1 +COC(=O)Nc1cccc(NC(=O)N(C)Cc2ccccc2C)c1 +COC(=O)c1ccc(C(=O)N(CCC#N)c2ccc(C)c(C)c2)nc1 +Cc1c[nH]c(=O)nc1-c1ccc(Br)cc1 +C=CCNC(=O)CSc1nnc(Nc2ccccc2F)s1 +Cc1nccn1-c1ncccc1NCc1csc(C2CC2)n1 +COc1ccc(C(C#N)N2CCN(C(=O)c3ccoc3C)CC2)cc1 +Oc1cccc(Cn2ccnc2-c2ccccc2)c1 +O=C(c1ccc2c(c1)OCO2)N1CCC2(C=Cc3ccccc3O2)CC1 +Cc1cc(F)ccc1S(=O)(=O)c1ccc(N)cc1 +CCCn1cc(NC2CCCCC2OC)ccc1=O +Cn1cc(C(=O)NCCCc2nc3ccccc3[nH]2)c2ccccc21 +C#CCN(CC(=O)NCC1CCC1)Cc1ccc(F)cc1 +CCc1nc2ccccc2n1C1CCN(C(=O)c2cscn2)CC1 +CCc1onc(C)c1NC(=O)c1csc2c1CCCC2 +COc1cccc(N2CCN(C(=O)NCc3ccccn3)CC2)c1 +CCC(NC(=O)NCc1c(C)n[nH]c1C)c1c(C)noc1C +Cc1ccc(SC(C)C(=O)N2CCN(c3ncccn3)CC2)cc1 +CS(=O)(=O)NCCSc1nc2ccccc2[nH]1 +CCCN(CCC)S(=O)(=O)Nc1cc(N)ccc1Cl +C#Cc1cccc(NCC(=O)Nc2ccc(C(=O)OCC)cc2)c1 +CNc1ncc(-c2nnnn2-c2ccccc2)c(C)n1 +Cn1ncc2c(=O)[nH]c(CN3CCOC(C(N)=O)C3)nc21 +CC1CCCC1NC(=O)c1c[nH]nc1-c1ccccc1F +CC(C)C(=O)N1CCc2ccc(NC(=O)c3cccs3)cc2C1 +CCCC(C)C(=O)Nc1ccc(C(=O)N2CCCCC2C)cc1 +O=C(NCc1cscn1)c1ccn(-c2cccc(Cl)c2)n1 +CC(C)N(CC1CC1)C(=O)c1cc(N)c(Cl)c(Cl)c1 +COc1ccc(S(=O)(=O)N2CCn3c(nn(C)c3=O)C2)cc1C +O=C(OCc1nc2ccsc2c(=O)[nH]1)c1cnc2ccccc2n1 +COCCCNC(=O)Nc1nnc(CC(C)C)s1 +CCOC(=O)C1=C(CC)NC(=O)NC1c1ccc(OC)cc1 +CCCNC(=O)Nc1ccc(CCN2CCOCC2)cc1 +Cc1ccc(C(=O)Nc2cccc(-c3ccc4c(c3)CCO4)n2)c(=O)[nH]1 +CCC(CNC(=O)c1cc(S(=O)(=O)NC)cn1C)c1ccccc1 +FC1(F)Oc2cccc(CN3CC(c4ccccn4)C3)c2O1 +CCc1nnnn1CC(=O)NC1(C#N)CCCCC1 +N#Cc1cccc(CS(=O)(=O)c2ccc(Cl)cc2)c1 +COc1ccccc1C(=O)Nc1ccc(N2CCCC2=O)cc1 +Cc1nc(C)c(-c2nnc(SCC(=O)c3ccccc3)o2)s1 +Cn1cccc1CNC1(Cc2cc(-c3ccccn3)on2)COC1 +O=C(NCCN1CCNC1=O)C(c1cccnc1)N1CCOCC1 +O=C(OCc1nc(C2CC2)cs1)c1ccncc1Cl +COc1ccccc1NC(=O)N1CCCC1C(=O)NC1CCCCC1 +CCCc1nc(CS(=O)(=O)c2nnc(NCC)s2)no1 +COc1ccc(CNC(=O)c2cccnc2N2CCCC2)cc1 +CNC(=O)c1ccc(CNC(=O)CCc2ccco2)cc1 +CCOC(=O)CN(CC)C(=O)c1c(C)oc(C)c1C +O=C(Cn1ncc2ccccc2c1=O)OC1CCCc2ccccc21 +O=C(CO)N1CCN(C(=O)c2ccn(-c3ccc(F)cc3)n2)CC1 +Cc1ccc(F)c2c1CCNC2CCOc1ccccc1 +Cc1cc(NC(=O)NCCO)ccc1C(=O)NC(C)C +COc1ccnc(C(=O)Nc2cc(C)ccc2Br)c1 +COc1ccc2[nH]cc(C(=O)NCCc3ccccn3)c2n1 +COc1ccc(NC(=O)CSc2nnc(NC(C)=O)s2)cc1 +Cc1ccc(SCC(=O)NC2c3ccccc3CC2O)cc1 +O=C(COc1ccccc1F)OCC(=O)N1CCCCCC1 +Cn1cnc(CNC(=O)NCC2(c3ccccc3F)CC2)n1 +Cc1cc(-c2cccc(Br)c2)[nH]c(=O)n1 +O=C(Nc1nc2ccccc2s1)c1ncccc1O +Cc1nn2c(CNC(=O)c3ccco3)c(-c3ccccc3)nc2s1 +Cc1n[nH]c2ncc(NC(=O)COc3ccc(CC(N)=O)cc3)cc12 +Cc1cc(C2CCC2)nc(NC2CC(=O)N(C(C)C)C2)n1 +CCCn1c(N)c(NC(=O)C2CCCCC2)c(=O)n(CCC)c1=O +C=CCCC(=O)N(c1ccc(O)cc1)S(=O)(=O)c1ccccc1 +COc1cc(NC(=O)C(C)C)ccc1NC(=O)c1ccco1 +CCCCN(CC)C(=O)Nc1cccc(CN2CCCC2=O)c1 +CC(C)C(C)NC(=O)c1ccc(NS(=O)(=O)c2ccccc2)cc1 +CSc1ccc(NC(=O)C(C)Oc2ccccc2C(N)=O)cc1 +COC(=O)CNc1cc(NC(=O)c2ccc3c(c2)OCO3)ccc1F +CNC(=O)COc1ccc(NC(=O)NCC2(C)CCCC2)cc1 +CNC(=O)c1cccc(OC(=O)c2cnn(-c3ccc(F)cc3)n2)c1 +O=C(c1ccccc1Cl)N1CCn2nc(-c3ccccc3)nc2C1 +COc1ccc(C(=O)N(C)CCc2ccccn2)c(Br)c1 +CC1(C)Oc2ccc(NC(=O)NC(CCO)c3ccccc3)cc2O1 +CC(C)(C)c1ccc2c(c1)CNCC2C(=O)NC1CC1 +O=C(Cc1cccc2ccccc12)Nc1ccccn1 +CC(C)C(=O)Nc1cccc(NCc2cn(C)nc2-c2cccnc2)c1 +CCC(=O)Nc1cccc(C(=O)N(CC)CCO)c1 +Cn1cc(NC(=O)NCc2cn3cc(Cl)ccc3n2)cn1 +CCNC(=O)CN(C)C(=O)c1cc(Br)ccc1F +Cc1ccc(-n2nnc(C(=O)N3CC4CCC3C4)c2C2CC2)cc1 +CN1C(=O)Cc2cc(NC(=O)Oc3ccccc3)ccc21 +CC1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1 +CCCn1nc(C)cc1CN(C)C(=O)c1cn2ccccc2n1 +CC(=O)NCC(=O)N1CCC2(CC1)CC(=O)N(C)C2 +COc1cc(N)c(NC(=O)Cc2ccc(F)cc2)cc1OC +O=C(CCC1CCCO1)Nc1ccn(-c2ncccc2Cl)n1 +Cc1nc(CNC(=O)c2c[nH]nc2-c2ccccc2F)sc1C +CCOc1ccc(S(=O)(=O)N(C)CC(=O)N(C)C)c(C)c1 +O=C(Nc1ccn(Cc2cccc3cccnc23)n1)C1CC1 +O=C(NC1CC(=O)N(c2ccc3c(c2)OCCO3)C1)c1ccco1 +CCCc1nnc(NC(=O)CCc2nc(C)no2)s1 +CCOc1cccc(CC(C#N)N2CCCCC2)c1 +CC1(C)COCN1C(=O)c1ccc(-n2cncn2)nn1 +CC(C)(C)NC(=O)CNC(=O)NC1CC2CCC1(C)C2(C)C +O=C(CCc1ccc(F)cc1)Nc1nncs1 +O=C(Cc1ccc2c(c1)CCO2)N(Cc1ccc(F)cc1)C1CC1 +Oc1cccc(-c2nc(-c3ccc(F)cc3)no2)c1 +Cc1ncsc1C(=O)N1CCCCC1c1nc2ccccc2[nH]1 +CCOC(=O)N1CCN(CC(=O)c2ccc(O)c(C)c2O)CC1 +Cc1ccc(CCNC(=O)c2sc(C(C)C)nc2C)s1 +CCS(=O)(=O)N1CCN(C(=O)c2ccc(F)cc2)CC1 +Nc1ccc(F)c(NC(=O)c2cc3ccccc3o2)c1 +Cc1cccc(OCC(C)NCc2cnc(N3CCOCC3)nc2)c1 +COC1(C)CC(N(C)C(=O)Cc2cccc(OCC#N)c2)C1(C)C +CC1COCCN1Cc1ccc(Br)cc1F +O=C(c1cccnc1Nc1cccc(F)c1)N1CCN(CCO)CC1 +O=C(CCc1ccsc1)NCCN1CCOCC1 +CC(CNC(=O)Cn1cc(C(F)(F)F)ccc1=O)N1CCOCC1 +CCOC(=O)C(N)c1ccnn1Cc1ccccc1 +Cc1ccc2nc(COC(=O)c3cc(F)ccc3F)cc(=O)n2c1 +O=C(C1CCCO1)N1CCN(c2ncccn2)CC1 +CCSc1cccc(C(=O)N2CCN(C(C)COC)CC2)c1 +CC(CC(=O)OCC1CC(=O)N(C2CC2)C1)c1ccc(F)cc1 +COCCCN1CC2=C(C1=O)C(c1ccc(F)cc1)NC(=O)N2 +Cc1sc2ncnc(NC(C)Cc3ccncc3)c2c1C +Cc1cc(C(=O)OCC(=O)Nc2ccccc2C)on1 +Cc1cc(C)cc(C(=O)Nc2ccc(Cn3cncn3)cc2)c1 +Cc1ccc(C(O)C2(n3nnc4ccccc43)CC2)cc1 +CCCc1cc(=O)n(CC(=O)Nc2ccccc2CC)cn1 +COc1cc(-c2noc(-c3cnc(C4CCCO4)s3)n2)ccn1 +O=C(NCc1csc(=O)[nH]1)c1cccc(-n2ccnn2)c1 +CN(CC(F)(F)F)C(=O)C1(c2ccc(F)cc2F)CCOCC1 +CCCNC(=O)c1cn(-c2cc(-c3nc(CC)no3)ccn2)cn1 +COc1ccc(F)c(NCC(=O)NCc2ccccc2)c1 +CC(Sc1ccccn1)C(=O)Nc1nnc(C(F)(F)F)s1 +O=C(Cc1cn2ccccc2n1)N1CCC(O)CC1 +Cc1cc(=O)c2cc(NC(=O)c3ccc(Cl)cc3)ccc2[nH]1 +CC(=O)Nc1ccc(F)c(NCc2cc(=O)n3ccccc3n2)c1 +COC(=O)c1sc2nc(Cc3ccc(O)cc3)[nH]c(=O)c2c1C +Cc1cc(C(=O)N2CC(=O)Nc3ccccc32)c2ccc(F)cc2n1 +Cc1noc(C2CCN(C(=O)c3ccnc(-n4cncn4)c3)CC2)n1 +CCOc1ccc(-n2c3c(cc(C#N)c2=O)C(=O)CC(C)(C)C3)cc1 +Cc1cccc(CNC(=O)Nc2ccccc2OCCC(N)=O)c1 +Cc1ccccc1NCc1cccc(C(=O)NCc2ccco2)c1 +Cc1ccc(SCC(=O)C(C#N)c2nc3ccccc3s2)nc1 +CCOC(=O)CCn1cnc2cc(Br)ccc2c1=O +CC(C)CC(=O)Nc1ccc(C(=O)Nc2c[nH]c(=O)[nH]c2=O)cc1 +CC(NC(=O)c1ccc(-c2cccnc2)nc1)c1ccc(F)cc1 +Cc1n[nH]c(SCC(=O)NCCc2ccc(C(C)C)cc2)n1 +CCOc1ccc(NC(=O)Cn2ccccc2=O)cc1OC +CCCOc1cccc(NC(=O)c2ccc(C(N)=O)cc2)c1 +CCOc1ccccc1C(=O)NCC(=O)Nc1ccc(F)cc1 +CCCc1cc(=O)[nH]c(SCC(=O)N(C)Cc2ccc(F)cc2)n1 +CCC(C#N)NC(=O)c1ccc(Br)cc1O +CC(C)(C)c1ccc(C=c2sc3ncnn3c2=O)cc1 +COc1ccc(NS(=O)(=O)c2cnc(N)nc2)cc1OC +Cc1[nH]c2ccccc2c1C(=O)Cc1nc2ccccc2c(=O)[nH]1 +O=C(CCOCC(F)(F)F)Nc1ccc(Br)cn1 +COc1ccc(Cl)c2c1N(C(=O)CCn1ccccc1=O)CCC2 +CCOC(=O)CN(C(=O)Cc1coc2cc(C)ccc12)C1CC1 +CCCNC(=O)CCCC(=O)Nc1ccccc1Cl +CC(C)CCCOCC(=O)c1ccc2c(c1)OCO2 +CCc1ccc(NC(=O)NC2C3CCC(C3)C2CO)cc1 +CCOc1ncccc1NC(=O)COc1ccc2c(c1)CCC(=O)N2 +NC(=O)C1CN(S(=O)(=O)c2cccs2)CCO1 +COc1cccc(NC(=O)C2C3CC4OC(=O)C2C4C3)c1 +COc1ccc(SCC(=O)N2CCCCC2)cc1 +CCc1ccccc1NC(=O)CCCNC(=O)c1ccco1 +O=C(OCC(=O)c1c[nH]c2ccccc12)c1ccc(O)cc1 +CCCOCC(=O)Nc1nc(-c2cccc(OC)c2)ns1 +COCCCN(C)C(=O)Nc1cc(C)cc(C)c1 +COCCNC(=O)C1CC(=O)N(c2cc(C)ccc2OC)C1 +COc1ccc(C)cc1NC(=O)Nc1cccc(N2CCNC2=O)c1 +COC(=O)c1ccsc1NC(=O)c1cccc(C)c1C +CCn1nnc2c(=O)n(CC(=O)N3CCCc4ccccc43)cnc21 +O=C(NCCCOC1CCCc2ccccc21)Nc1ccccn1 +Cc1nnc(-n2nnc(C(=O)OC(C)C)c2N)s1 +CCOC(=O)CCc1c(C)nn(-c2ccc(N3CCCC3)nn2)c1C +CCc1nnc(SCc2nc(C(C)C)nn2-c2ccnc(C)c2)o1 +COC(C)C(=O)Nc1cccc(NC(=O)NCc2ccccc2C)c1 +CC(C)(O)CCc1cccc(C(=O)NCC2(O)CCCCC2)c1 +Cc1ccc(Cl)c2c1CCNC2c1cc[nH]c(=O)c1 +O=C(Nc1ccc(F)cc1)C1CCN(C(=O)c2ccco2)CC1 +Cc1ccc(-c2noc(CCC(=O)NC(C)(C)C)n2)cc1 +CCC(C)(C)NS(=O)(=O)c1cc(Br)cnc1N +N#Cc1cc(F)ccc1NC(=O)NCc1ccccc1OC(F)F +C=CCn1c(C)nnc1SCC(=O)C(C)CC +O=C(NCCCc1n[nH]c(=O)[nH]1)C1CCOc2ccc(Cl)cc21 +Cc1cccc(NC(=O)N(CCC#N)Cc2ccccn2)c1Cl +CCN(CC)C(=O)CN(C)c1cc(N)cc(F)c1 +CCOc1ccc2cc(C(=O)N(C)C)c(=O)oc2c1 +FC(F)(F)c1ccnc(N2CCCC(c3nnc4ccccn34)C2)n1 +Cc1nnc2n1CCN(CC(=O)NCC(C)(C)N1CCOCC1)C2 +C=CCNC(=O)C(OCC)c1ccc(O)c(Cl)c1 +CCCc1cc(C(=O)N2CCN(Cc3csc(C)n3)CC2)n(C)n1 +COc1cccc(SCC(=O)N(C)Cc2ccco2)c1 +Cc1cccc(OCc2nc(-c3ccc(C#N)cn3)no2)c1 +Cn1ccsc1=NC(=O)c1ccnc(-n2cncn2)c1 +Cc1csc(Cn2ccc(=O)c3sccc32)n1 +CCOc1ccc(NC(=O)CCc2c(C)nn(C)c2C)cc1Cl +COCCNC(=O)Nc1ncc(Cc2ccccc2Cl)s1 +Cc1ccc(CNC(=O)Nc2ccn(C)n2)c(OC(C)(C)C)c1 +O=C(C1CCCCC1)N1CCC(c2ncc3ccccn23)CC1 +Cc1ccc(OCC(=O)NC(CO)C(O)c2ccc(N)cc2)c(C)c1 +COc1ccccc1C1CC1c1nc(-c2ccc(C#N)cn2)no1 +CC(C)(NCC(=O)NC1(C#N)CCCC1)c1ccc2c(c1)OCCO2 +N#Cc1cccc(S(=O)(=O)N2CCC(C(N)=O)CC2)c1 +Cc1nc2ccccc2n1Cc1nnc2n1N=C(N)CS2 +CC(=O)c1cccc(S(=O)(=O)NCC(C)(C)c2ccncc2)c1 +Cc1cccc(CS(=O)(=O)c2nc3ccccc3[nH]2)c1 +Cc1ccc(Cl)cc1S(=O)(=O)n1ccnc1C +O=C(Cc1ccc2c(c1)CCCC2)OCCNC(=O)c1ccncc1 +COc1ccc(OC)c(NC(=O)Nc2ccccc2)c1 +CN(CCc1ccccn1)C(=O)CNC(=O)N(C)C1CCCCC1 +COc1ccc(CNC(=O)NCCNC(=O)c2cccnc2)cc1 +Cc1nn(C)c(=O)c(C(=O)NCC(C)(C)c2ccccc2)c1C +Cc1ccccc1CNC(=O)CN1CCN(Cc2ccccc2)C1=O +CC(C)n1cc(CC(=O)NCc2cccn2C)c2ccccc21 +CC(NC(=O)COc1ccccc1Cl)c1ccc2c(c1)OCCO2 +CCOC(=O)c1cccnc1SCCn1c(=O)oc2cccnc21 +Cc1cc(C(=O)NC(C)C)ccc1NC(=O)NCc1ccn(C)c1 +Cc1csc(N2CCN(c3ccc(C#N)cn3)CC2)n1 +CCOC(=O)N1CCN(CC(=O)N(C2=CCCCC2)C2CC2)CC1 +Cc1nc2nnc3ccc(C(=O)N(C)C)cc3c2n1Cc1ccccc1 +Cc1n[nH]c(C(=O)NC(C)c2c(C)nn(C)c2C)c1Br +O=C(NCCNc1cnccn1)c1ccc2ccccc2n1 +Cc1nc2cc(NCc3c[nH]nc3-c3ccc(F)cc3)ccc2o1 +CC(=O)Nc1ccc(Cl)cc1NC(=O)c1ccc(=O)n(C)n1 +N#CCCN(CCC#N)C(=O)COc1cccc(C#N)c1 +Cc1cccc(C(C)C)c1NCC(O)c1ccc2c(c1)OCO2 +COc1cc(CN2CCN3C(=O)NCC3C2)cc(OC)c1OC +O=C(c1ccccc1Nc1ccccc1)N1CCC1 +COC(=O)c1ccc(C(=O)Nc2ccc3c(c2)oc(=O)n3C)nc1 +Clc1cc(COc2ccc(-n3cnnn3)cc2)cc2c1OCCO2 +COC(=O)c1ccc(NC(=O)COc2cccc(NC(C)=O)c2)cc1 +Cc1ccc(NC(=O)CSc2nccn2Cc2ccco2)c(C)c1 +O=c1[nH]cnc2c1cnn2Cc1cccc(Cl)c1 +O=C(Nc1cccc2cn[nH]c12)c1c(F)cccc1F +Cc1nn(C)c(C)c1CC(=O)N=c1[nH]c2ccccc2n1C(C)(C)C +CCC(C)NC(=O)Nc1cnn(-c2ccccc2)c1 +O=C(Cn1nnc(-c2ccccc2)n1)NCCc1cccc(Cl)c1 +CCn1nc(C)cc1C(=O)Nc1nc2c(s1)CC(C)CC2 +COc1ccc(OC)c(CC(=O)Nc2ccc(-n3cccn3)cc2)c1 +COC(=O)c1cc(S(=O)(=O)NCC(C)c2ccccc2)c[nH]1 +O=C(CNc1ccc(F)cc1F)Nc1ccc(F)cc1 +CC(NC(=O)N1CCC(NS(C)(=O)=O)CC1)c1ccccc1F +Cc1nn(C)c(C)c1S(=O)(=O)NC(C)c1nncn1C +O=C(OCc1ccccc1)N1CCC(COCCO)C1 +Cc1cc(NC(=O)c2ccc(CNC(=O)c3cccs3)cc2)no1 +COCc1cccc(C(=O)NCc2cccc(OC)c2OC)c1 +CC(C)(C)C(=O)CNC(=O)c1ccc(Cn2cccn2)o1 +O=C(CSc1nc2ccccc2o1)OCC(=O)c1ccccc1 +CCN(CC(=O)NC(C)(C)C)C(=O)c1ccc(F)c(COC)c1 +CCOCc1cccc(NC(=O)C2CCN(c3cnccn3)CC2)c1 +CC(=O)N1CCc2cc(C(=O)NCc3sccc3C)ccc21 +CCn1c(-c2cnn(C)c2NC(=O)c2ccc(C)o2)nc2ccccc21 +CCC(C(=O)NCCSc1nnc(C)s1)n1cccn1 +COC(=O)CCn1nc(C)c(CN2CCOC3(CCC3)C2)c1C +NC(=O)CSc1nnc(CN2CCOCC2)n1-c1ccccc1 +O=C(NCCc1ccccc1)c1cnn2cc(Br)cnc12 +COc1ccc(F)c(NC(=O)Cc2csc(C)n2)c1 +COc1cc(OC)cc(OCCc2cc(C)[nH]n2)c1 +CC(C)OCCCNC(=O)N1CCN(c2ccccc2)CC1 +Cc1ccc(NC(=O)NCc2cn(-c3ccccc3)nn2)s1 +CCCOc1ccc(OC(=O)c2cc3c([nH]c2=O)CCCC3=O)cc1 +Cc1ncsc1COC(=O)CNC(=O)c1ccccc1 +Cc1nn(C)c(C)c1CCC(=O)N1CCc2ccc(Cl)cc2C1 +CNC(=O)Cn1nnc(CO)c1Cc1c[nH]c2ccccc12 +CC(=O)NC1CN(C(=O)c2ccncc2)CC1C(C)C +CNC(=O)CN1C(=O)C(C)Oc2ccc(N)nc21 +COC(=O)CC1CN(Cc2cncs2)CCO1 +Cc1cc(N2CC(N3CCOCC3)C2)nc(-c2ccccc2O)n1 +CCOC(=O)Cc1c(C)[nH]n(-c2ccccc2)c1=O +CC(C)NC(=O)Cn1cnc2sccc2c1=O +COc1ccc(OC)c(C(=O)Nc2sc(C)c(C)c2C#N)c1 +Cc1noc(C)c1CC(=O)N1CCN(Cc2ccc(F)cc2F)CC1 +CC1Cc2ccccc2N1CC(=O)N1Cc2ccccc2C1 +CNC(=O)c1cc(NC(=O)CC(C)(C)C)ccc1Cl +CC(C)C(=O)Nc1cccc(NC(=O)Cc2ccc(F)c(F)c2)c1 +CCN(Cc1cccc(C)c1)C(=O)Nc1ccnc(C(=O)N(C)C)c1 +COCCNc1nc2c(s1)CCc1ccccc1-2 +CC(NS(=O)(=O)c1cn[nH]c1)c1ccc(Cl)cc1Cl +O=S(=O)(NCCc1ccc(F)cc1F)c1cc(F)cc(F)c1 +Cc1nn(C)cc1CN(C)C(=O)c1nc(C(C)C)nc2c1OCCO2 +CC(C)(C)CC(=O)NCCNC(=O)c1ccco1 +CCN1CCN(C(=O)c2cc(C)no2)c2ccccc21 +Cc1cc(S(=O)(=O)N(C)C)cc(NCc2cccc(F)c2)c1C +O=C(c1ccc(O)nc1)N1CCCC(CCc2ccccc2F)C1 +COC(C)c1cccc(NC(=O)c2cc(F)c(F)c(F)c2)c1 +Cc1ccc(CNC(=O)COC(=O)c2cccc(F)c2)cc1 +COc1ccccc1S(=O)(=O)N(C)Cc1cnn(C)c1 +CC(C)C(Sc1nccn1C)C(=O)NCc1ccccc1F +O=C(Nc1cccnc1)C1COCC(=O)N1Cc1ccccc1 +COc1ccccc1-c1nn(C)cc1C(=O)NC1CC1 +Cc1ccc(-c2noc(Cn3nnc(-c4cccs4)n3)n2)cc1 +COc1ccc2c(c1)OCC(C(=O)N1CCc3ncccc3C1)C2 +CCc1nc(CNCC(c2cccc(C)c2)N2CCOCC2)cs1 +COc1ccc(N2CC(NC(=O)NC(C)(C)C)CC2=O)cc1 +CCC(=O)Nc1cccc(C(=O)NC(C)c2cc(C)sc2C)c1 +CN(CC(=O)Nc1cccc(F)c1)C(=O)Cc1cn2ccsc2n1 +CCc1cc2c(=O)[nH]c(CC(=O)c3c[nH]c4ccccc34)nc2s1 +COCCNC(=O)c1c2c(cn1-c1ccccc1)CCC2 +COc1ccc(C(=O)NCc2ccc(Cl)cc2Cl)nn1 +CCC1CN(C)c2ccccc2CN1C(=O)c1cccc(C)n1 +CC(=O)OC1c2ccccc2C(=O)N1C1CCCCC1 +O=C(Cn1c(=O)[nH]c2c(oc3ccccc32)c1=O)NCc1ccccc1 +CN(C(=O)c1c(F)cccc1Cl)c1ccc(O)cc1 +O=c1[nH]c2cc3c(cc2cc1CNCCN1CCOCC1)OCO3 +Cc1oc(C)c(C(=O)NC(C)Cc2ccccc2F)c1C +CC(C)C(NC(=O)NC(C1CC1)C1CC1)c1nc(C2CC2)no1 +COC(=O)C1CC1C(=O)N1CCN(Cc2ccccc2OC)CC1 +COc1ccccc1C1Nc2ccccc2C(=O)N1Cc1cccnc1 +Cc1cc(C)c(S(=O)(=O)NCc2cnn3ccccc23)c(C)c1 +CCOC(=O)N1CCc2nc(NC(=O)c3ccc(F)cc3)sc2C1 +COc1ccc2nc(NC(=O)NCc3ccc(OC)nc3)sc2c1 +Cc1nc(NC2CC2)sc1C(=O)NCCC(C)C +Cc1ccc(NC(=O)COc2cccc3c2CCC3=O)cc1F +Cc1nnc2sc(Cc3cccc4ccccc34)nn2c1=O +CC(=O)c1cccc(NC(=O)C2(C#N)CCCC2)c1 +O=C(Nc1cc(Br)ccn1)c1ccc(Cl)cc1 +N#Cc1cc(F)cc(C2NCCc3cccc(F)c32)c1 +N#Cc1cc(Br)ccc1NCc1nnc2n1CCCCC2 +CCN(CC1CC1)C(=O)c1scnc1C1CC1 +Nc1nccnc1C(=O)OCC(=O)NCC1CCCCC1 +FC(F)(F)COCCNc1ccc(Br)cn1 +CN(C)C(=O)c1cc(-c2cnn(-c3ccccn3)c2)nc2ccccc12 +CC(=O)NCC1CCCN(C(=O)Nc2cccc3cccnc23)C1 +COc1cc(N2CC3COCC3(CC(=O)N(C)C)C2)ncn1 +O=C(CCOc1cccc2c1CCCC2)NCCO +CCOc1ccc(Cc2nn3c(C#N)c(C)nc3s2)cc1 +C#CCNc1cc(S(=O)(=O)N(C)C(C)C)ccc1C +Cc1ccccc1NCC(=O)Nc1cccc(N2CCCC2=O)c1 +Cc1c(C(=O)NCC2CC2c2ccccc2)cnn1-c1ccncc1 +COCc1nn2c3c(cnc2c1-c1cccc(Cl)c1)C(=O)CCC3 +Cc1nc(C)c(C(=O)Nc2ccc3c(c2)nc(C2CC2)n3C)s1 +CC1CCCN(C(=O)Cn2cnc3ccsc3c2=O)C1 +COc1cc(CN2CCCC(c3ccn[nH]3)C2)ccc1S(C)(=O)=O +Cc1cc(Cl)ccc1NC(=O)C1CCN(C(=O)c2ccco2)CC1 +Cn1ncc2c(N3CCCCC3)nc(NCCCO)nc21 +Cc1nc(-c2ccccc2F)cc(N2CCOCC2)n1 +CC(=O)N1CC(C(=O)Nc2ccc3c(c2)oc(=O)n3C)C1 +CCCCN(CCCC)c1cn[nH]c(=O)c1Cl +CC1CN(Cc2ccnn2C)C(c2ccccc2)CO1 +CCC1(C)OC(=O)N2CCc3cc(OC)c(OC)cc3C21C +Cc1ccc(Cn2nnc(C(=O)Nc3cccc(C)c3)c2N)cc1 +O=C(NCCCN1CCCCCC1=O)c1cccc(-c2ccoc2)c1 +CC(C(=O)Nc1c[nH]cc(Br)c1=O)C1CC1 +O=C(Cc1ccccc1F)NCC(O)c1ccccc1 +CCc1nnc(CNC(=O)c2ccc3nc(C)c(C)nc3c2)s1 +CC(C(=O)NCc1csc(=O)[nH]1)c1ccccc1F +O=C(NC1CC1)c1ccc(Cl)c(S(=O)(=O)N2CCCC2)c1 +COCCC(=O)NC(c1ccccc1)c1cccc(F)c1 +Cn1ccnc1CN1CCCN(C(=O)c2cnn(C)c2C2CC2)CC1 +COCCOCC(=O)N(C)Cc1cnc(C)s1 +CNc1snc(C)c1C(=O)OCC(=O)c1ccc2c(c1)OCO2 +COc1ccc(C(=O)NCc2cccc(C)c2)cc1OC +Cc1ccc(C)c(NC(=O)C2CCCN(C(=O)c3ccoc3)C2)c1 +CCCCNC(=O)C1CCN(C(=O)c2ccc(Cl)cc2)CC1 +CC(=O)c1ccc(NC(=O)CCc2ccsc2)cc1 +CC(=O)c1sc(CCOc2ccc(C)cc2)nc1C +O=C(CNC(=O)c1ccc(OC(F)F)cc1)NCc1ccccn1 +CCCn1nc(C)c(CNc2cccc(Cn3cnnc3)c2)c1C +Cc1ccc(NC(=O)C2CC(=O)N(C3CC3)C2)cc1C +Cc1ccc2oc(=O)c(S(=O)(=O)N3CCC(C)CC3)cc2c1 +O=C(c1ccc2[nH]cnc2c1)N1CCN(C(=O)c2ccco2)CC1 +N#Cc1cccc(Nc2nccc3ccc(N)cc23)c1 +Cn1c(C(F)(F)F)nn(Cc2nc3ccccc3[nH]2)c1=O +CCCCN(CC(F)(F)F)C(=O)c1cc(F)cc2[nH]cnc12 +O=C(c1cccs1)N1CCN(Cc2cccc3cccnc23)CC1 +CCOC(=O)N1CCN(Cc2nc(Cc3cccc(F)c3)no2)CC1 +COc1ccc(Cl)cc1NC(=O)Nc1ccc(-n2ccnc2)nc1 +COCC(=O)N1CCC(C(=O)NC(C)CCc2ccco2)CC1 +Cc1cccc(CC2Oc3ccc(N)cc3N(C)C2=O)c1C +Nc1ncccc1COc1c(Cl)cccc1Cl +CCCCN(CCCC)C(=O)c1ccc2c(c1)CCN2C(C)=O +c1ccc(CNCCc2ccc(-n3cccn3)cc2)nc1 +NS(=O)(=O)c1ccc(NC(=O)c2ccccc2O)cc1 +COC(=O)c1cc(CNC(=O)C2(c3cccc(F)c3)CCC2)oc1C +COc1ccc(-n2nc(-c3ccccc3)cc2C(=O)NC(C)C)cc1 +Cc1c(C(F)(F)F)n[nH]c1NC(=O)C1COCCO1 +Cc1nn(CC(C)C)c(C)c1CC(=O)Nc1cc(C#N)ccc1Cl +CCOCC1CCCN(C(=O)NC(C)Cn2cncn2)C1 +CCOc1ccc(C(C#N)NC(=O)C(C)(C)C)cc1 +CCn1c(SC(C)C(=O)NC2CCCC2)nnc1-c1ccncc1 +CCc1nc2n(n1)CCCC2NC(=O)CCc1c(C)nn(C)c1C +Cc1cc(C)n(CCNC(=O)c2ncc[nH]2)c(=O)n1 +CCOc1cccc(C(=O)Nc2ccc(CNC(N)=O)cc2)c1 +CC(NC(=O)c1ccc(F)cc1Cl)c1nc2ccccc2[nH]1 +O=S(=O)(c1cc(Cl)cc(Cl)c1)N1CCN(C2CC2)CC1 +O=C(Nc1ccccn1)c1c(Cl)cccc1Cl +CC(C)Sc1ccccc1NC(=O)c1ncn(-c2ccccc2)n1 +CC(C)NC(=O)Cc1cn2cc(Br)ccc2n1 +Cc1cccc(N(Cc2ccccc2)S(C)(=O)=O)c1 +Cc1ccccc1OC1CN(C(=O)c2ccc3[nH]c(=O)[nH]c3c2)C1 +CC(O)CCC(=O)NCCc1nc2ccccc2[nH]1 +COc1cc(SC)ccc1C(=O)Nc1ccccn1 +COc1cccc(C2N=C(Cc3ccco3)C(=O)O2)c1 +CCCCn1nc(C(=O)Nc2cc(Cl)ccc2C(N)=O)ccc1=O +COc1c(Br)cncc1Br +Cc1ccc(CC(C(N)=O)c2cccc(N)c2)cc1 +CCCn1c(=O)c(N2CCN(C(=O)C3CC3)CC2)nc2ccccc21 +COCC1CCN(C(=O)c2cccc(S(=O)(=O)N3CCC3)c2)C1 +CCCC(=O)N1CCCC1C(=O)N=c1[nH]nc2cc(C)ccn12 +c1ccc2cc(OCc3noc(C4CC4)n3)ccc2c1 +Cc1nn(Cc2nc3c4ccccc4ncn3n2)c(C)c1Cl +O=C(Nc1cc(-c2cccs2)nn1CCO)c1cccs1 +COc1ccc(C(=O)N2CCC(c3ccncc3)CC2)c2ccccc12 +CCCc1ccc(C(=O)C(C#N)c2nnc3n2CCCCC3)cc1 +CC(C)N(CC(N)=O)C(=O)c1cccc(OCc2cccs2)c1 +CN(CCCCN1CCOCC1)c1nnc(C2CC2)o1 +Cn1cc(S(=O)(=O)NCc2cccnc2OC2CCCC2)cn1 +Cc1nc2ccccc2c(=O)n1Cc1ccccc1 +CSc1nsc(SCC(=O)NC2CCCCC2C)n1 +O=C(Cn1ccc(-c2ccco2)n1)NCc1ccc(F)cc1 +N#Cc1ccc(N2CCC(C(=O)Nc3nnc4ccccn34)CC2)nc1 +O=C(NCC1(c2ccccc2)CC1)N1CCC2(CCOC2)C1 +Cc1nn(C)c2ncc(NC(=O)CCOc3ccccc3)cc12 +Cc1cc(C(=O)NCCCOC2CCCCC2)c2c(C)noc2n1 +COCC(C)NC(=O)c1cc(-c2ccccc2F)no1 +CCCc1noc(CN(C)CCc2ccccn2)n1 +Cc1cc(CNC(=O)COc2ccc(Cl)c3cccnc23)c(C)o1 +CCCCn1nccc1NC(=O)c1sc(C)cc1OC(F)F +Cc1cc(C(=O)Nc2nc3ccc(Cl)cc3s2)on1 +CC(C)OC(=O)CN1CCN(c2ccccc2)CC1 +O=C(NCc1ccc(F)cc1)c1ccc(-c2cscn2)cc1 +Cc1cccc(-c2ccc(C(=O)N3CCCC3)cn2)c1 +CCOc1cccc(C(=O)NC(CO)C(O)c2ccc(N)cc2)c1 +CC(C)CNC(=O)NC(C)Cc1c(F)cccc1F +CCn1cc(C(=O)N2CCOC(C(N)=O)C2)c(C(C)C)n1 +COC(=O)c1ccc2c(c1)nc(CCO)n2CC#N +Cc1cc(S(=O)(=O)NCCCO)c(Cl)cc1Cl +Cc1c(C#N)c2ccccc2n1CC(=O)N1CCc2ccccc21 +O=c1cc2[nH]nc(O)c2nn1-c1cccc(C(F)(F)F)c1 +CN(Cc1cccc(C(F)(F)F)c1)CC(O)c1ccccc1 +O=C(CNC1(c2ccc(F)cc2)CCOCC1)NCc1ccco1 +Cc1ccc2c(c1)NC(=O)C(C)(C(=O)NCC1CCCC1)O2 +CCOc1ccccc1C(=O)N1CCC(C)CC1C +CCN(C(=O)c1ccc(F)c(NC(C)=O)c1)C(C)C(C)C +Cn1c(C2CC2)nc2cc(C(O)Cn3cc(N)cn3)ccc21 +Cc1cc(C)c(OCC(=O)Nc2cc(C)on2)c(C)c1 +Cn1nccc1CNC(=O)NC1(c2cccc(Cl)c2)CC1 +CC(C)(C)CC(=O)Nc1nnc2n1CCCS2 +O=C(NCc1ccccc1)C1CC(=O)N(c2cccc(Cl)c2)C1 +Cc1ccc(C(=O)NCc2cccc(N)c2)cc1F +c1ccc(C2CNc3ccccc3N2Cc2ccncc2)cc1 +CC(C)(C)OC(=O)N1CCC2(CC1)CNc1cc(F)ccc1C2 +CC1CCc2cc(F)ccc2N1S(=O)(=O)c1ccc(N)cc1 +COc1ccc(NC(C)=O)cc1NC(=O)CCSc1ccccc1 +Cc1cc(O)ccc1S(=O)(=O)c1ccc(O)cc1C +COc1ccc(C(=O)Nc2ccc3c(c2)CC(=O)N3)cc1F +COC(=O)c1c(NC(=O)c2ccc3ncsc3c2)sc(C)c1C +CCc1onc(C)c1NC(=O)Nc1cccc(CC(=O)OC)c1 +O=C(CCc1cccs1)Nc1cccc(N2CCNC2=O)c1 +CCc1cccc(NC(=O)COC(=O)c2cccc(O)c2)c1 +Cc1ncsc1C1NCCc2cccc(OC(F)F)c21 +O=C1CN(C(=O)NCC2(c3ccccc3F)CC2)CCN1 +CC(C)c1ccc(-c2nnn(CC(=O)c3ccc[nH]3)n2)cc1 +CCC(CC)N(CCO)C(=O)Cc1ccc(Br)cc1 +Nn1c(SCc2cc(-c3cccs3)on2)nnc1-c1ccco1 +CN(C)S(=O)(=O)c1ccc(SCC2CCCO2)nc1 +Cc1ccnc2nc(C(=O)Nc3ccccc3C(C)C)nn12 +Cc1ccc(F)c(NC(=O)N(C)Cc2cnn(C)c2)c1 +CCN(CCO)C(=O)Nc1ccc(Sc2nc(C)cs2)cc1 +O=C(NCc1ccc(Cn2cncn2)cc1)c1ccc(F)cc1Cl +O=C(CC1OC(CNC(=O)N2CCOCC2)C(O)C1O)NC1CC1 +O=C(NCc1ccccc1Cn1cccn1)c1ccccn1 +Cc1cccc(C)c1NC(=O)c1ccc(N2CCOC2=O)cc1 +CC(C)c1nc(CCNC(=O)c2ccc(F)cc2F)cs1 +Cc1ccc(C(=O)Nc2ncc(C(N)=O)s2)c(C)c1 +O=C(CNC(=O)c1ccccc1Cl)Nc1c(F)cccc1F +O=C(Nc1ccccc1)C1CCCN(S(=O)(=O)c2ccccc2)C1 +N#Cc1ccsc1NC(=O)CN1CCN(c2ccccn2)CC1 +CCCN(CC(=O)OCC)C(=O)c1c(C)noc1C +Cc1cc(C(C)NC(=O)Nc2ccc(F)c(C#N)c2)c(C)o1 +Nc1ccccc1S(=O)(=O)N(CC(F)(F)F)C1CC1 +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)NCCCO +CC(=O)c1ccc(C(=O)NC2CCC(C)CC2)s1 +CNC(=O)c1cccc(NC(=O)COC(=O)c2ccc(O)cc2)c1 +Cn1c(=O)oc2cc(NC3CCCN(C(=O)OC(C)(C)C)C3)ccc21 +CC1CC1C(=O)Nc1ccc(F)cc1C(=O)NCC(=O)N1CCCC1 +CNC(=O)NCC(=O)NC(CC(N)=O)C1CCCCC1 +COCCOC(=O)c1ccccc1CS(N)(=O)=O +CC(NC(=O)N1CCOCC1C)c1ccc(-c2ccncc2)cc1 +COc1cc(CNC(=O)C2CCCC2)ccc1OCC(F)(F)F +OCc1c(-c2ccco2)nc2sc(COc3ccccc3)nn12 +Cn1cc(CNCC(O)c2cccc(Cl)c2)c(-c2cccnc2)n1 +COc1cccc(C(=O)Nc2ccccc2C(C)=O)c1OC +CC(c1ccco1)N(C(=O)NCc1noc(C(C)(C)C)n1)C1CC1 +COCCCNS(=O)(=O)c1ccc(OC)c(N)c1 +Cc1nc2ccccc2n1CC(=O)NCC1CCC1 +COc1cc(C(=O)N(C)Cc2cnn(Cc3ccccc3)c2)ccc1C +CCSc1nc(C)cc(C(=O)N(C)Cc2ccc(OC)cc2)n1 +O=C(CC1(Cn2cnnn2)CCCCC1)NC1CCCC1 +CNC(=O)COC(=O)c1ccc(COc2ccccc2C#N)o1 +COC(=O)Cn1cc(NC(=O)CCNC(C)=O)cn1 +CC(C)OC(=O)CNS(=O)(=O)c1cccc(Br)c1 +CC1CC2CC(O)CCC2C(C)N1C(=O)OC(C)(C)C +O=C(Nc1nc(-c2ccc3c(c2)CCO3)cs1)c1ccc[nH]1 +COc1ccc2nc(N3CCCC3)c(C#N)cc2c1 +O=S(=O)(NCc1ccc(F)c(Cl)c1)c1ccccc1F +Cc1ccc(C(N)=O)cc1NS(=O)(=O)c1ccc(F)cc1 +N#CCCCOc1cccc(NC(=O)N2CCC3(CC2)OCCO3)c1 +O=C(Cc1csc(-c2ccsc2)n1)Nc1cccc2cn[nH]c12 +O=C(Cn1nnc(-c2cccs2)n1)NCC1CCOC1 +COc1ccccc1C(=O)Nc1cnc2scnn2c1=O +c1csc(-c2noc(-c3n[nH]c4ccccc34)n2)c1 +COCCCN(C)S(=O)(=O)c1ccc(C(C)=O)cc1 +COC(=O)C(C)(C)CNC(=O)N1CCCC(C)C1 +Cc1c(C(=O)OCC(C)C)[nH]c2c1C(=O)CC(c1ccco1)C2 +CCNC(=O)CN(C)C(=O)c1cccc(OC)c1 +CCCn1nnnc1CSc1ccccc1O +Cc1ccc(C)c(OCC(=O)Nc2ccnc3ccc(F)cc23)c1 +c1cncc(CN2CCCn3cnc(COCc4ccco4)c3C2)c1 +COc1ccc(Cl)cc1-c1n[nH]c(SCc2nnc(C)o2)n1 +CC(=O)c1ccc(NC(=O)c2ccccc2)cc1C +CCN(CC)C(=O)CCC(=O)Nc1cccc(C)n1 +CC(=O)Nc1ccc(OS(=O)(=O)c2ccc(F)c(F)c2F)cc1 +COC(=O)c1ccsc1NC(=O)CCc1ccccc1 +CCn1nc(C)c(NS(=O)(=O)c2c(C)sc3ccccc23)c1C +COc1ccc(F)c(NC(=O)N(C)Cc2ncnn2C)c1 +CCOc1cc(C)ccc1NC(=O)NCC(C(C)C)N1CCOCC1 +Cc1cc(C(=O)N(C)CCC#N)c2c(C)nn(C)c2n1 +Cc1cnc2n(c1=O)C(CC(=O)NCCC1=CCCCC1)CS2 +CNC(=O)C1CCCN1c1ccc(N)c(OC)n1 +COC(=O)c1ccc(S(=O)(=O)N2CCN(C)CC2)cc1 +CN(C)c1ccccc1C#CCNC(=O)c1cccnc1 +Nc1ccc2[nH]c(-c3ccc4[nH]c(-c5ccccn5)nc4c3)nc2c1 +O=C1CN(C(=O)COc2ccccc2)S(=O)(=O)c2ccccc21 +COC(=O)c1nonc1NCCCc1ccccc1 +CC(C)N(CC(N)=O)C(=O)Cc1c(F)cccc1Cl +O=c1[nH]c2ccccc2nc1SCc1ccc2ccccc2n1 +COc1cc(-c2ccccc2)ccc1C1NC(=O)C2COCCN21 +Cc1ccsc1C1CC(O)=Nc2c1cnn2C(C)C +O=C(NCCOc1cccc(F)c1)N1CCC2(CC1)OCCO2 +O=S(=O)(Nc1cccc(Cl)c1)c1cccnc1 +CNS(=O)(=O)c1ccc(CC(=O)C(C)C)cc1 +Cn1nc(-c2cccc(F)c2)c2c1CCCC2CC#N +O=C(c1cccnc1)N1CCC(OCC2CC2)C1Cc1cccnc1 +O=C(Nc1ccccc1)c1c(-n2cnnn2)sc2c1CCCC2 +CC(=O)N1CCc2cc(C)c(S(=O)(=O)NC3CC3)cc21 +COc1ccc(F)cc1NC(=O)c1ccc(N(C)C)cc1F +O=C(CCCOCc1ccccc1)N1CCOc2ccc(F)cc21 +COCCN1CCN(C(=O)c2c[nH]cc2-c2ccc(F)cc2)CC1=O +Cc1ccc(C#N)cc1NCc1nc(C2CC2)no1 +CCN(CC)C(=O)C(NC(=O)C1CC12CCOCC2)c1ccccc1 +Cc1ccncc1NC(=O)NCC1(c2cccc(F)c2)CCOCC1 +Cc1ccc2[nH]c(SCc3ccccn3)nc2c1 +CSc1ccc(C(=O)Nc2ccc3c(c2)COC3)cc1 +Cc1ccc(C(c2c(O)n[nH]c2C)C(C#N)C#N)cc1 +Cc1ccc(NC(=O)c2ccc3ccccc3n2)c(O)c1 +CC(C)COCCCC(=O)Nc1ccc(Cl)cc1N +O=C(Cn1cnc2cc(F)c(F)cc21)NCCOc1ccccc1 +CC1(C)CN(CCC(N)c2ccc(Cl)cc2)CCO1 +COC(=O)c1ccc(S(=O)(=O)Nc2cccc(OC)c2)cc1 +Cc1ccc(F)cc1NC(=O)Cn1c(=O)oc2ccccc21 +NC(=O)C1Cc2ccccc2CN1C(=O)CSc1ccncc1 +Cc1cccc(NC(=O)c2cc(=O)c3cc(N)ccc3o2)n1 +Cc1nc(C2NC(=O)c3cccc(C)c3N2)cs1 +CN(Cc1ccc(OC(F)F)cc1)S(N)(=O)=O +COc1ccccc1N1CCN(C(=O)NC2CC2)CC1 +O=C(NCc1ccc(-n2cccn2)nc1)N1CCC(c2ccccc2)C1 +CCOc1cc(F)ccc1NC(=O)CCC(=O)c1cccs1 +CCC(C)Sc1ccc(NC(=O)N(C)CCn2cnnc2)c(C)c1 +Cc1csc(C(C)NC(=O)c2cccc(CCC(C)(C)O)c2)n1 +CCc1ccc(Cl)c(CC)c1NC(=O)NC(CC)CO +Cc1ccc(NC(=O)NCc2ncccc2C)cc1S(C)(=O)=O +N#CCCn1ncc2c(NC3CCCC(C(F)(F)F)C3)ncnc21 +CCCNC(=O)C1CCCN(C(=O)Cc2cccc(OCC#N)c2)C1 +CCc1nc2c(N)cccc2n1CC(=O)Nc1ccccc1C +COc1ncccc1CNC(=O)c1cc2ccccc2n1C +CC(C)NC(=O)C1CCN(Cc2cncs2)CC1 +CSc1ccccc1C(=O)NCCn1ccc(-c2ccncc2)n1 +CC1CC1CNC(=O)Nc1cnn(CC(N)=O)c1 +COCc1ccc(C(=O)N2CCOCC2C2CC2)o1 +CCOC(=O)Cn1nc(C)n(-c2ccccc2F)c1=O +CCCCCNS(=O)(=O)c1ccc2c(c1)OCCCO2 +O=C(c1ccncc1)N1CCC2(CC1)COC(COCC1CC1)C2 +Nc1ccc2c(c1)N(C(=O)CCc1cccc(Cl)c1)CCC2 +C=CCNC(=O)C(C)NC(C)c1cccc(C(F)(F)F)c1 +Cc1cccc2nc(CNC(=O)c3cc(=O)[nH]c4ccccc34)cn12 +Nc1ccc(F)c(NC(=O)CCn2ccccc2=O)c1 +c1ccc2c3c(ccc2c1)CCNC3c1cncnc1 +Cc1ccc(NC(=O)c2ccc(F)c(C(F)(F)F)c2)cc1C(N)=O +COC(=O)Cc1csc(Cc2ccc(F)cc2)n1 +CNc1nnc(SCC(O)c2ccccc2)s1 +CCOc1ncccc1NC(=O)N1CCN(Cc2cc(C)no2)CC1 +Cc1nc(-c2cccc(NC(=O)c3cc(-c4ccco4)[nH]n3)c2)oc1C +Cc1ccc(S(=O)(=O)NCc2cn(-c3ccccc3)nn2)c(F)c1 +N#Cc1ccc(-c2nc3cc(S(N)(=O)=O)ccc3[nH]2)cc1 +O=C(c1ccccc1O)N1CCN(Cc2cccc3c2OCO3)CC1 +Nc1ccc(NCCNC(=O)c2cccc(Cl)c2)nc1 +NC(=O)c1ccc(NC(=O)C2CN(C(=O)c3cccs3)C2)cc1 +O=C(Cn1ccc(=O)[nH]c1=O)Nc1ccccc1F +COCc1cc(N2Cc3cnn(Cc4ccc(F)cc4)c3C2)ncn1 +CC(C(=O)N1CCOCC1)S(=O)(=O)c1nnc2ccccn12 +Cc1nn(C)c(C)c1CC(=O)Nc1nc2c(s1)CCC2 +COc1cc(NCc2ccc(-c3noc(C)n3)cc2)ncn1 +CCOC(=O)c1csc(NC(=O)c2c(C)nn(C)c2C)n1 +CCC1CCCCN1C(=O)C(C)S(=O)(=O)c1ccc(Cl)cc1 +Cc1cc(C)c2c(c1)NC(=O)C2CC(=O)NCCOc1nonc1C +COc1cccc(NC(=O)N2CCCC2C(=O)NC(C)C)c1 +CCOc1ccc(C(C#N)N(C)C(=O)c2cccc(F)c2)cc1 +O=C(NCCNC(=O)c1ccoc1)NC1CCCC1 +Cc1nc(C)c(C(=O)OCC(=O)c2ccc3[nH]c(=O)[nH]c3c2)s1 +CC(=O)N1CCN(C(=O)CCNC(=O)Cc2cccc(C)c2)CC1 +CCCN(Cc1nnc(-c2ccco2)o1)C(=O)c1ccoc1C +CN(C)S(=O)(=O)c1ccc(CNc2ncccn2)s1 +CCN(Cc1ccccc1)C(=O)CCc1nc(-c2cccnc2)no1 +NC(=O)c1ccc(C(=O)NC(c2ccc(Cl)cc2)C2CCC2)cc1 +CCC(C)(C)NC(=O)CSc1ccc(F)c(F)c1 +O=S(=O)(c1ccccc1Cl)N1CCOCC1 +CC(C)(C)OC(=O)NCC(=O)N1CCCC1c1ccc2c(c1)OCO2 +COc1ccc(-c2nccc3occc23)c(-n2cccn2)c1 +CC(C(N)=O)N1CCN(C(=O)c2ccc(OC(F)F)cc2)CC1 +CNc1nc(C2CCCC(C)C2)nc2sccc12 +CC(Sc1nnnn1CC1CCCO1)c1ncc(C(C)(C)C)o1 +COc1ccccc1N(C)C(=O)c1cncc(Br)c1 +CCCCCNC(=O)Cc1noc2ccc(N)cc12 +COC(=O)C(C)C(NCc1ccc(C#N)cc1)c1ccccc1 +Cc1occc1C(=O)N1CCC2(CCN(c3cnn(C)c3)C2=O)C1 +CCc1noc(CC)c1CNC(=O)c1ccnc2ccccc12 +COC(=O)c1ccccc1S(=O)(=O)c1cnc2ccccc2n1 +CCCCNC(=O)Cc1csc(NC(=O)c2cccs2)n1 +Cc1ccc(NC(=O)c2nc(C)n(-c3ccccc3C)n2)cc1C +Cc1ccc(F)c(NS(=O)(=O)c2ccc(O)cc2)c1 +CCC(=O)Nc1nc(-c2ccco2)c(-c2ccncc2)s1 +N#CC1(c2cc(Br)ccc2F)CCC1 +CSc1nc(-c2ccco2)nn1S(=O)(=O)c1ccc(C)cc1 +Cc1cc(NCc2ccco2)nc(-c2cccnc2)n1 +CCCC(C#N)NC(=O)c1cccc(Cn2nc(C)cc2C)c1 +CCOC(=O)c1csc(NC(=O)c2sc(C)nc2C(C)C)n1 +O=C(CCNS(=O)(=O)c1ccc(F)c(F)c1)N1CCOCC1 +COc1cc(OC)c(NC(=O)NCc2ncn(C)n2)cc1F +CC1CCCC(C)N1C(=O)N1CCC(C(=O)Nc2ccccc2)CC1 +CC(C)C(=O)NCCNC(=O)c1nc(C2CC2)n(-c2ccccc2)n1 +CC(Cc1ccsc1)NC(=O)N1CCC(Oc2cccnc2)C1 +C#CCC(OC(=O)c1cnn(-c2ccccc2C)c1)c1ccccn1 +COc1cccc(C(CO)Cc2ccc3c(c2)OCCO3)c1 +Cn1c(SCC(=O)NCC(F)(F)F)nnc1-c1ccco1 +Nc1cc(S(=O)(=O)Nc2ccc(F)c(Cl)c2)ccc1O +CCOC(=O)CN(C)C(=O)C(C)n1nc(C)cc1C +CC(C)CNC(=O)C1CCCN(C(=O)CCc2cccs2)C1 +CC(CCc1ccccc1)NC(=O)c1cnn(C)c1 +COc1ccc(C(=O)NCCc2nnc3ccccn23)cc1F +C#CCNC(=O)C1CC1c1cccc(Br)c1 +Cc1ccnc(N2CCOc3c(O)cc(-c4cccnc4)cc3C2)n1 +CN(Cc1ccccn1)C(=O)NCc1ccc(Cl)cc1Cl +Cc1cc(C(=O)N(C)C(C)c2ccco2)c(C)n1-c1nccs1 +COc1cccc(NC(=O)c2oc3cccnc3c2N)c1 +CC(C)(C)c1ccc(S(=O)(=O)N2CCCC(O)C2)cc1 +O=C(NCC(O)c1ccc(F)c(F)c1)c1ccc(F)cc1 +COc1cc(OC)cc(C(CC(N)=O)c2c[nH]c3ccccc23)c1 +COc1ccc(Oc2ccc(NC(=O)Cc3ccc[nH]3)cn2)cc1 +Cn1cc(-c2nc(CN3CCc4nn(C)c(=O)cc4C3)cs2)cn1 +Cn1cc(C(N)=O)cc1C(=O)C(C#N)c1nc2ccccc2[nH]1 +Cc1cnn(CC2CCCN2C(C)c2nc3ccccc3c(=O)[nH]2)c1 +Cn1cc(-c2ccccc2NC(=O)C(C)(C)C)cn1 +Cc1nc2c(cc1C(=O)NC1CCCC(C)C1)c(C)nn2C +CCc1cccc(NC(=O)c2cccc(NC)n2)c1 +COc1ccc(C2(O)CCC(C)CC2)cc1OC +N#Cc1cnn(CCOC(=O)c2cccc3ncccc23)c1N +Cn1ncc2c(N3CCC(c4nc5ccccc5[nH]4)CC3)ncnc21 +COc1cc(Cl)c(C)cc1N1CCN(CCO)CC1 +N#Cc1ccc(NC2C(=O)Nc3ccc(F)cc32)cc1 +O=C(Cn1nc2c(cc1=O)CCCCC2)NC1CC1 +COc1ccccc1C1(C(=O)N(C)Cc2cccs2)CCOCC1 +Cc1cc(C)n(C2CCCN(C(=O)CN(C)c3cnccn3)C2)n1 +COC(CNC(=O)c1c(F)cccc1F)c1cccc(F)c1 +CCC(NC(=O)c1cscn1)c1ccc(Cl)cc1 +Cc1cc(CNc2nc3nonc3nc2N2CCCC2)nn1C +CCCc1nnc(SCC(=O)N(CC)CC)n1N +COC(=O)c1ccc(C(=O)NC2CCCC2)s1 +CCC(CC)N(CCOC)C(=O)Nc1ccc2c(c1)COC2 +COC(=O)C1CCCCCC1NC(=O)Cn1c(C)csc1=O +O=C(Nc1cccnc1)c1cc2cnsc2s1 +N#CCc1sc2nc(-c3ccco3)cc(C(F)(F)F)c2c1N +CCc1ccc(C2CC(=O)NCc3nc4sccn4c32)o1 +COc1ccc(-c2csc3ncc(CC#N)n23)cc1C +CCCOC(=O)C1=C(C)Nc2ncnn2C1c1ccccc1Cl +O=C(Nc1nccs1)c1ccc2ncsc2c1 +OCCSc1nnc(NCCc2cccs2)s1 +O=C(Cn1cncn1)NCCSc1ccccc1 +O=C(Cc1ccc[nH]1)N1CCC(Cc2cccc(F)c2)CC1 +CN(C)c1ccc(S(=O)(=O)NC(C)(C)C)cc1 +CCOC(=O)CC(C)CNC(=O)C1C2CCCC21 +COc1ccc(S(=O)(=O)n2c(C)nc3ccccc32)cc1OC +COCCNc1nc2c([nH]1)c(=O)n(C)c(=O)n2C +O=C(Nc1ccc(OCc2noc(C3CC3)n2)cc1)NC1CCCC1 +CN(C)C(=O)c1cccc(OC(=O)c2cc(C(N)=O)cs2)c1 +Cc1nn(C)c2sc(C(=O)Nc3ccccc3C(=O)C(C)C)cc12 +O=C(NCCO)Nc1cccc(Oc2ncccn2)c1 +COc1ccc(OC)c(NC(=O)c2c(C)[nH]c(C(C)=O)c2C)c1 +CC(Sc1nncn1C)C(=O)c1ccc2c(c1)CCC2 +C#CCN1C(=O)C(C)Nc2cc(Br)ccc21 +Cc1c(C(=O)OCc2cccnc2)oc2c(F)cccc12 +CCNc1ccc(C(=O)NCC(=O)NC2CC2)nn1 +N#Cc1ccc(NCC(O)c2ccc(F)c(N)c2)cc1 +COc1ccc2sc3ccccc3c(=O)c(=O)c2c1 +CCN(CCO)C(=O)CC1C(=O)NCCN1Cc1cccc(F)c1 +Cc1cccc(C(=O)NC(C(=O)NCc2cccs2)C(C)C)c1 +CCCCOC(C)C(=O)Oc1ccc2c(c1)OCO2 +Cc1ccc2c(c1)N(CC(=O)NC(C)C)C(=O)CO2 +NC(=O)c1cccc(CC2CCN(c3nc(N)nc4[nH]cnc34)C2)c1 +CCc1nc(CN2CCN(C(=O)CCCOC)CC2)cs1 +OC(COCc1ccco1)Cn1cnc2ccccc21 +CCOC(=O)c1c(C)[nH]c(C(=O)N2CCCC(C(F)(F)F)C2)c1C +CCOC(=O)C1Sc2nnc(C)n2NC1c1ccc2c(c1)OCO2 +COc1ccc(C2CCCN2C(=O)c2ccc(-n3cccn3)cc2)cc1 +O=C(NCC1CN2CCCCC2CO1)c1ccncc1F +CCn1ncc(NC(=O)Cn2cc(C)c(-c3ccc(OC)cc3)n2)n1 +CCOc1ccc(F)c(C(=O)NC(COC)C(N)=O)c1F +CC(C)(C)NC(=O)COc1ccc(C(=O)NC2CCCC2)cc1 +CCc1nnc(NC(=O)CSc2nnc(C(C)C)o2)s1 +CCCCN(CC)c1ccc(S(C)(=O)=O)cc1S(C)(=O)=O +Cc1ccc(C(=O)NCC(O)c2cccn2C)cc1C +O=C(NC1CCCN(Cc2ccccc2)C1=O)C1CC=CCC1 +O=C(Nc1cccn(Cc2ccccc2)c1=O)c1ccccc1F +NS(=O)(=O)c1ccc2c(c1)CCN2S(=O)(=O)c1cccs1 +Cc1nnc(C2CCN(c3nccc(C(F)(F)F)n3)C2)o1 +N#Cc1ccc(N2CCC(F)CC2)c(C(F)(F)F)c1 +O=C(COc1ccc(F)c(Cl)c1)NCc1ccco1 +CCOc1cc(OCC)cc(C(=O)NCc2ccco2)c1 +O=C(Cn1ccc2ccccc21)NCC1CCOC1 +CC=CCCNC(=O)NCCc1cccc(C(=O)NC)c1 +O=C(NCC(F)(F)F)c1cc(-c2ccncc2)nc2ccccc12 +O=C(CNC(=O)C1CCCC1)Nc1ccccc1Br +Cc1c(CNC(=O)NCc2ccc(-c3ccccc3F)o2)cnn1C +CN(C)C(=O)c1cccc(COc2ccccc2C(N)=O)c1 +Cc1ccc(Cl)cc1CNc1cnccc1C#N +CC(O)(CNC(=O)c1cnc2ccccn2c1=O)c1ccc(F)cc1 +COc1ccc(OC)c(NCC(=O)NC2CCCCC2)c1 +CC(C)C(C)NC(=O)NCc1ccccc1-n1ccnc1 +CN(Cc1ccc(F)cc1)C(=O)COc1ccc(-c2nnco2)cc1 +Nc1cncn1Cc1ccccc1Br +COc1cccc2c1CCC2NC(=O)NCc1nnc2ccccn12 +COCCc1nc(C)c(-c2csc(NC(C)C)n2)s1 +O=C(NCc1cc(-c2ccccc2)on1)Nc1ccccn1 +COc1ccc(-c2cn3nc(C(F)(F)F)sc3n2)cc1 +O=C(CSc1ccncc1)NCC(=O)N1CCCC1 +CCC(=O)Nc1[nH]nc2c1c(C)nn2Cc1cccc(OC)c1 +Cc1ccc(OC(C)C(=O)Nc2ccc3c(c2)COC3)cc1 +CN(CCc1ccc(F)cc1)Cc1cnc2ccc(C#N)cn12 +CCCc1c(C(=O)NC(C)c2ccncc2)[nH]c(C)c1C(=O)OC +COC(=O)CCCNC(=O)c1ccc(-n2cnnn2)cc1 +Cc1ccnc2cc(OCc3nccs3)ccc12 +CCOCC(=O)N(Cc1ccc(O)c(OC)c1)C1CC1 +CC(C(=O)Nc1ccc2c(c1)CC(=O)N2)c1ccccc1F +Nc1cccc(CC(=O)NCCC2=CCCCC2)c1 +COc1ccc(NC(=O)c2nc(C)sc2-c2cccc(F)c2)cn1 +CCC(C)C(=O)Nc1c(C(=O)N2CCOCC2)oc2ccccc12 +CC1CC(NC(=O)C2CN(S(=O)(=O)C3CC3)C2)CC(C)(C)C1 +CCC(NC(=O)c1cc2ncccn2n1)c1nc(C)c(C)s1 +O=S(=O)(c1cccs1)N(CCO)Cc1ccccc1 +CCCNC(=O)c1cccc(C(=O)Nc2cc(C)ccn2)c1 +CCCN1C(=O)C(C)(C(=O)NC2CCCCCC2)Oc2cccnc21 +COc1cc(NCc2ccccc2F)nc(OC)n1 +Cn1nc(C2CC2)nc1-c1ccccc1Br +O=C(Nc1ccc(Br)cc1)Nc1nc[nH]n1 +CCC(C)NC(=O)N(C)Cc1cc(C(=O)OC)c(C)o1 +CCCCN1C(=O)C(CC)N(C)c2ccc(C(C)=O)cc21 +CCN(C)C(=O)c1cccc(S(=O)(=O)N2CC(C)CC(C)C2)c1 +CC(C)CN(C)C(=O)C(C)NC(=O)c1cccs1 +CC1(C)CC(=O)c2cnc(NCc3ccc4c(c3)OCO4)nc2C1 +O=C(Nc1nncs1)c1csc2ccccc12 +CN(C)c1ccccc1C#CCNC(=O)Cn1cccn1 +CCn1ccc(NC(=O)c2c(Cl)c(C)nn2CC)n1 +O=C(NCC#CCOc1ccccc1F)c1ccsc1 +CCSc1ccc(C(=O)Nc2nccs2)cc1 +CC(=O)NC(C)(C)c1noc(C=Cc2csc(C)n2)n1 +Cc1ccccc1CNC(=O)CN1CCN(c2ccccc2F)CC1 +Nc1cccc(NC(=O)CCOCC(F)(F)F)c1 +O=C(NCc1ccc(-c2ccccc2)cc1)c1cnn2ncccc12 +CC(C)Sc1ccccc1C(=O)N1CCCCC1 +CN(C)S(=O)(=O)c1ccc(C(=O)NCCCCO)cc1 +Cc1noc(C)c1C(=O)Nc1nc(-c2c[nH]c3ccccc23)cs1 +Fc1cccc(-c2nnn(Cc3ccncc3)n2)c1 +N#CCSc1ccccc1C(=O)Nc1cccc(CO)c1 +CSc1ccccc1NC(=O)COC(=O)c1ccccc1 +Cc1ccoc1C(=O)Nc1sc2c(c1C(N)=O)CCCC2 +N#Cc1cccc(S(=O)(=O)N2CCCCC2C(=O)N2CCCC2)c1 +COc1ccc(Cl)cc1CNc1cccc(NC(N)=O)c1 +COc1ccccc1CCC(=O)N1CCC(Cc2nncn2C)CC1 +Cc1cc(NCC(=O)N(C)CC(F)(F)F)nc(C)n1 +O=C(c1ccc(=O)[nH]c1)N1CCC(c2nnc(C(F)(F)F)o2)CC1 +CNC(=O)c1ccc(CNS(=O)(=O)Cc2ccccc2)cc1 +CC(=O)N1CCN(C(=O)c2cnn(C)c2N)CC1 +CC(Sc1ccc(O)cc1)C(=O)N(CCC#N)c1ccccc1 +Cn1cccc1C(=O)Oc1cccc(Br)c1 +Cc1nc(-c2ccccc2)sc1CNC1CCc2ncnn2C1 +COc1ccc(NC(=O)c2ccc(SC)cc2)cc1F +CN(C)c1ccc(Cl)cc1NC(=O)NCc1ccncc1 +CCOc1ccc(C(=O)NC(Cc2ncc[nH]2)c2ccccc2)cc1 +Cc1cccc(Sc2nccnc2SCC(=O)NC2CC2)c1 +O=C(COc1ccc2nccnc2c1)NCc1ccc(F)cc1 +CC(C)c1noc2ncc(C(=O)N3CCC(C(N)=O)CC3)cc12 +COc1ccc(C2CCCN2Cc2ccccc2C#N)cc1 +Cn1nccc1C(=O)Nc1ccc2ncsc2c1 +O=C(CCn1ccccc1=O)Nc1cccc(OCc2ccccn2)c1 +C#CCNC(=O)CN1CCN(C(=O)N(C)C)CC1 +O=C(NCc1ccccc1C(F)(F)F)c1ccc(Cn2cccn2)o1 +Brc1cccc(Cc2nccn2Cc2cccnc2)c1 +CC(=O)Nc1ccc(CC(=O)NCc2ccc(C)n2C)cc1 +COCCC(=O)c1ccc(OC)c(-c2ccccc2)c1 +CCOC(=O)C(C)Oc1ccc2c(C)cc(=O)oc2c1 +CC1(C)Cc2nc3ncn4ncnc4c3cc2CO1 +Nc1cc(C(=O)N2CCN(C(=O)c3ccccc3)CC2)n[nH]1 +N#Cc1cc(N)cnc1Oc1ccc(F)cc1Br +COC(=O)NCC(=O)N1CCC(OCc2ccccc2F)CC1 +Cc1cc(CC(=O)N(CC2CCC2)c2ccccc2)no1 +CCOC(=O)c1oc2ccccc2c1CNC(=O)NCC1CCCO1 +CCCc1n[nH]cc1C(=O)N1CC=C(c2ccc(F)cc2)CC1 +Cc1nnc(CN(C2CC2)S(=O)(=O)c2ccc(C#N)cc2)n1C +CCOC(=O)C(N)c1nnc(C)n1-c1ccccc1 +CC(C)CNC(=O)c1ccc(S(=O)(=O)NCC2CCCO2)cc1 +C=CCNC(=O)Nc1cccc(C(=O)N(C)c2ccccc2)c1 +N#Cc1ccc(NC(=O)Cn2cnc3ccccc32)cc1 +O=C(CCNS(=O)(=O)c1cccs1)N1CCCC1 +CC(=O)c1ccccc1NCC(=O)NCc1cccc(Cl)c1 +COc1ccc2oc(C(=O)NC3CCCCC3)nc2c1 +Cc1cccc(C(=O)N2CCC(Oc3ccccn3)CC2)c1 +Cc1noc(C)c1CC(=O)Nc1nc(-c2ccncc2)cs1 +O=C(N1CCOCC1)N(Cc1ccccc1)c1ccccn1 +Cc1cccc(C)c1NC(=O)Nc1ccc(CCO)cc1 +COc1ccc(C(=O)N2CCN(c3cccc(C)c3C)CC2)cc1 +Cc1cc(Nc2ncnc3c2CCN(C(=O)c2ccccc2)C3)[nH]n1 +Cc1ccc(-c2cc(=O)c3cc(F)ccc3o2)cc1N +CCCn1c(=O)c2c3c(cnc2n(C)c1=O)C(=O)CCC3 +c1cc(COC2CCC3C2OCCN3C2CCOCC2)ccn1 +NC(=O)N1CC(NC(=O)c2cscn2)C2OCCCC21 +COC(=O)Nc1ccc(CNC(=O)COc2ccccc2C)cc1 +N#Cc1c[nH]c(C(=O)NCC(O)(c2ccccc2)C(F)(F)F)c1 +O=C(Nc1cccnc1)c1cccc(-n2cnnn2)c1 +NC(=O)c1ccccc1OS(=O)(=O)c1ccc2ccccc2c1 +CCNc1ccc(Cl)cc1NC(=O)C(C)OCC +Cn1cc(CNc2cnn(-c3ncccn3)c2)cn1 +CCCCS(=O)(=O)Nc1cnn(C2CCOCC2)c1 +C=CCNC(=O)Nc1ccc(NC(=O)c2ccc3[nH]cnc3c2)cc1 +Cc1nn(CC(=O)NCc2ccccn2)c(=O)c2ccccc12 +NC(=O)CCNS(=O)(=O)CCc1ccccc1 +O=C(Nc1ccccc1)c1ccc(S(=O)(=O)N2CCOCC2)cc1 +CCn1nc(C)c(C(C)NC(=O)CCc2[nH]nc3c2CCCC3)c1C +CCCCS(=O)(=O)N1CCCc2ccc(N)cc21 +CC(C)N(C)C(=O)CCc1cccc(Br)c1 +Cc1nc(CC(=O)N2Cc3cnc(CC(C)C)nc3C2)cs1 +CCNC(=O)N1CCN(CC(=O)NC(C)c2ccccc2)CC1 +COc1ccc(C(=O)Nc2c(C)nn(-c3ccc(C)cc3)c2C)cc1 +CCOC(=O)c1[nH]c(C)c(C(=O)C(C)N(C)C(=O)c2ccco2)c1C +CCN(Cc1ccccc1C)C(=O)NCc1ncn(C)n1 +CCN1CC(C(=O)Nc2ccccc2N2CC(C)OC(C)C2)CC1=O +O=C(Cn1ncc2ccccc21)NC(Cc1ccccc1)C1CC1 +O=C1CC(C(=O)N2CCc3ccc(O)cc3C2)CN1CC1CC1 +Cc1ccccc1CNC(=O)CCc1nc2ccccc2oc1=O +CCOc1ccc(C(C)NC(=O)N2CCOCC2C)cc1OCC +CCCS(=O)(=O)N1CCC2(CC1)OCCCO2 +Cc1nc(C2COCCO2)n(-c2cc(Cl)ccc2Cl)n1 +COc1ccc(C(=O)NCC(=O)Nc2ccc(N(C)C)nc2)cc1 +Cc1ccc2c(c1)c(=O)c(C(=O)NCCC(C)C)nn2C +O=C(Nc1nc[nH]n1)c1ccc(Oc2ccc(F)cc2)cc1 +CC(C)C(=O)NC1CCN(c2cccc(Cl)c2C#N)CC1 +Cc1n[nH]cc1NC(=O)COc1cccc(Cl)c1 +Cc1cnc(CCNC(=O)NC2CCCOc3ccccc32)s1 +Cc1ccc(OCc2nc(CN)cc(=O)[nH]2)cc1C +CCNC(=O)CN1CCSc2ccc(N)cc21 +O=C(CCn1ccccc1=O)NC1(c2ccc(Cl)cc2)CCC1 +CC(=O)Oc1cccc(C(=O)Nc2cc(C)ccc2C)c1 +Cn1ncc(C(=O)NCCN2CCCCCC2=O)c1-n1cccc1 +COc1cccc2c1OCC(=O)N(C(C)c1cccs1)C2 +Nc1ccc(C#Cc2ccc(Br)cc2)cc1 +CC(C)N(CCO)S(=O)(=O)c1cc(C(N)=O)n(C)c1 +COc1ccc(CNc2ncnc3cc(OC)c(OC)cc23)cc1 +CNC(=O)C1CN(C(=O)Nc2ccc(C)cc2C)CC12CCCC2 +CCCC(O)CNS(=O)(=O)N1CCC(C(C)(C)C)CC1 +Cc1cccc(C(C)C)c1NC(=O)c1cccc(N(C)C)c1 +Cc1nc(NC(=O)c2ccc(F)cc2)nc2cc3c(cc12)OCO3 +COCCNC(=O)C1CCC2C(CCN2Cc2c(C)noc2C)O1 +COc1ccccc1C(=O)NCCC(=O)Nc1nc(C)c(C)s1 +COc1ccc(C)cc1NC(=O)C12CCC(C)(C(O)C1)C2(C)C +Cc1nc(NC2CCCN(C(N)=O)C2)c2c(C)csc2n1 +CCSc1nc(C)cc(C(=O)NC2CCCc3ccccc32)n1 +CC(=O)N1CCc2ccc(NC(=O)C3CCC3)cc2C1 +O=C(c1ccc(O)cc1)N1CCN(Cc2cc(F)ccc2F)CC1 +CCOc1ccc(CN(C)C(=O)CCCO)cc1 +CNS(=O)(=O)c1cc(C(=O)Nc2cc(C)cc3cccnc23)co1 +Cc1cc(C)c(C(=O)N(C)CC2CCOC2)c(C)c1 +CSc1nc(N)nc(C2COc3ccccc3O2)n1 +CN(C)C(=O)C(NCCc1c[nH]c2ccccc12)c1ccccc1 +CN(C(=O)c1cn(C)nc1-c1cccs1)c1ncccc1F +Cc1cnc(NC2CCN(S(=O)(=O)CC(C)C)CC2)nc1 +CC(C)c1ccc(S(=O)(=O)Nc2ccc3[nH]c(=O)oc3c2)cc1 +CN(C)c1ccccc1NC(=O)c1cncc(Br)c1 +CCCS(=O)(=O)N1CCC2C(COC2CNc2ncccn2)C1 +CCOCCNCc1nc2cc(Cl)ccc2c(=O)[nH]1 +Cc1c(N)cc2c(c1C)OC(c1ccc(F)cc1)C(=O)N2 +Cc1csc(CN2CC3CC(CC(=O)NC4CC4)OC3C2)n1 +Cc1ccc(CCCNC(=O)c2ccncc2)c(C)c1 +Cc1oc(C(C)C)nc1C(=O)N1CCN(Cc2ccc(F)cc2)CC1 +CN(C1CCCN(c2ccccc2)C1)S(C)(=O)=O +CC(NC(N)=O)C(=O)N(C)Cc1cc(Br)cs1 +Cc1ccc(C=CCC(=O)NCc2n[nH]c(=O)[nH]2)cc1 +COC(=O)CN1CCN(C(=O)c2ccc(C(C)C)cc2)CC1 +COCCC(=O)Nc1ccc(N2CCNC2=O)cc1 +CCC(NC(N)=O)c1ccccc1OCC(=O)N1CCCC1 +CCCOC(=O)c1cn(-c2cccc(F)c2)c(=O)c2ccccc12 +CCOC(=O)c1coc(-c2ccc(Br)cc2)n1 +CCN(CC)C(=O)C1=C(C)NC(=O)NC1c1ccccc1 +COC(=O)c1cc2c([nH]c1=O)CC(c1ccc(F)cc1)CC2=O +Cc1nccc(-c2cccc(NC(=O)NC(C)CO)c2)n1 +O=C(NCc1ccncc1)c1nc(-c2ccc3[nH]ccc3c2)no1 +COC(=O)c1c(NC(=O)Cc2ccc3c(c2)OCO3)sc(C)c1C +O=c1cc(CN2CCCC2CO)[nH]c2c(Cl)cccc12 +CN(Cc1ccccn1)C(=O)Cc1cccc(OCC#N)c1 +CC(C)CNC(=O)c1cn(C2CCCN(C(=O)C3CCC3)C2)nn1 +c1ccc(-c2n[nH]c(SCC3CCCCO3)n2)cc1 +Cn1ncc(C(=O)Nc2ccc(C(N)=O)cc2)c1-n1cccc1 +CCC(C)C(=O)NCCNc1cccc(F)c1C#N +Cc1nc(N(C)C)ncc1C(=O)N1CCCCC1CCn1cccn1 +CCN(C1CC1)S(=O)(=O)c1cccc2cc(C)cnc12 +O=C(NCCOc1cccc(C(F)(F)F)c1)NCC1CCCO1 +CCOc1ccc(NS(=O)(=O)c2ccc(C(N)=O)cc2)cc1F +O=C(NC1CCCC1)c1c(F)cccc1C(F)(F)F +Cc1cnc(NC(=O)CCNC2N=CN=C3N=CN=C32)s1 +Cn1c(SCc2cccc(C#N)c2)nc2ccccc2c1=O +Cc1ncc(CNc2ccc3c(c2)COC3)n1-c1ccccc1 +Cc1cc(C)c(NC(=O)CNc2ccc(F)cc2)c(C)c1 +C=CCn1c2ccccc2c2nnc(SC)nc21 +Cc1ccc(S(=O)(=O)N2CCN(C3CCCC(C)C3)CC2)cc1 +COc1cccc(N2CCC(CNC(=O)c3c(C)nn(C)c3C)C2)c1 +Cc1cc(S(N)(=O)=O)n(Cc2ccccc2Cl)n1 +Cc1cc(C(=O)Nc2nc(C)c(C)s2)nc(N2CCOCC2)n1 +COc1cccc2c1N(Cc1nn3c(=O)cc(C)nc3s1)CCC2 +CCc1ccccc1NC(=O)Cn1nnc2ccccc2c1=O +COc1ccc(-c2nnc(NC(=O)OCC(C)C)s2)cc1OC +CCCn1cc(NC(=O)c2cc(F)c(F)c(F)c2F)ccc1=O +COc1ccc(C(C)C)cc1C(=O)C1CCC(=O)O1 +COc1ccc(OCc2noc(CNC(=O)c3cccnc3)n2)cc1 +CC(=O)c1nnn(Cc2ccc(F)cc2)c1-c1ccccc1 +N#Cc1cccc(S(=O)(=O)NCCN2CCOCC2)c1 +COc1ccc2c(c1)C1(CCN(S(C)(=O)=O)C1)C(=O)N2 +CCc1cc(NC(=O)c2ccc(F)c(COC)c2)n(C)n1 +CC(=O)Nc1cccc(NC(=O)C2CCN(C(=O)N(C)C)CC2)c1 +Nc1cc(N2CCN(c3nc4ccccc4s3)CC2)nc(N)n1 +CNC(=O)NCC(=O)NCc1ccc(Br)cc1C +CC1CN(C(=O)c2ccc(Cl)cc2Cl)C(C)CO1 +CCC(C)NC(=O)NCC(C)Cn1nc(C)cc1C +Cc1cccc(S(=O)(=O)CCC(=O)Nc2ccccc2Cl)c1 +Fc1ccccc1Cc1nnc(NCc2cnc3cnccn23)o1 +Cn1nccc1C(=O)N1CCOC(Cc2ccccc2)C1 +CCCOc1cccc(CNC(=O)c2csc(-c3nc[nH]n3)n2)c1 +CCCCN(C)C(=O)Cn1c(CC#N)nc2cc(C)ccc21 +C=CCNC(=O)c1ccc(=O)n(-c2ccccc2)c1 +Cc1cnn(CC2CCCN2C(=O)c2sccc2C2CC2)c1 +O=C(CN1C(=O)COc2ccccc21)NCc1ccccc1F +Fc1ccc(CN2CCN(c3ncccn3)CC2)c(Cl)c1 +COC(=O)c1ccc(F)c(S(=O)(=O)NCc2ccc(C)s2)c1 +Cc1ccc(C(=O)NC(C)c2cccc(N3CCCC3=O)c2)c(=O)[nH]1 +O=C(C1CC2CCC1O2)N1CCc2cc(Cl)cc(Cl)c2C1 +CCc1nc(N)n(CC(=O)Nc2ccccc2F)c(=O)c1C +Cn1c(=O)c2cc(C(=O)Nc3nccs3)sc2n(C)c1=O +Cc1ccc(NC(=O)NCc2cc(Cl)ccn2)cc1-n1cnnn1 +CCCCN(CC(N)=O)C(=O)C1CCN(c2ccc(F)cc2)C1=O +Cc1cc(NC(=O)N2CCCC2C(C)(C)O)nn1-c1cccc(F)c1 +Cc1ccc(CC(=O)NC(C)c2ccccc2Br)cn1 +CC(=O)OCn1ncc(Br)c(Br)c1=O +Cc1cnc(CNC(=O)Nc2cc(-c3ncco3)ccc2C)s1 +CC(C)CN1CCOC(CNC(=O)c2cn3ccccc3n2)C1 +CC1=NC(C(F)(F)F)(C(F)(F)F)NC(=O)N1C(C)C +CC1(C(=O)Nc2ccc(Cl)cn2)Cc2ccccc2C(=O)O1 +C=CCn1c(SCCc2c(C)noc2C)n[nH]c1=O +CCC(=O)NC1CCCN(C(=O)Nc2c(C)noc2CC)C1 +O=C(NCc1cc2ccccc2o1)NCc1nnc2n1CCC2 +Cn1ncc(C(=O)Nc2ccc(C(N)=O)cc2)c1N +Cc1cc(C)nc(NC(=O)c2ccc(N)c(C)c2)n1 +COc1ccc(CN(C)c2ncnc(SC)c2C#N)cc1OC +Cc1ccc(O)c(C(=O)c2cnn(-c3nc(=O)cc(C)[nH]3)c2)c1 +COc1ccc(OCCS(=O)(=O)N=c2cc(C)cc[nH]2)cc1 +COC(=O)C(NC(=O)c1cc[nH]n1)c1ccc(Br)cc1 +COCc1cccc(CNC(=O)c2c(C)n[nH]c2C)c1 +COCCCN(C)C(=O)c1cccc(NC(N)=O)c1 +CCCS(=O)(=O)c1ccccc1C(=O)Nc1ccc(F)cc1F +CC(C)CC(C)NS(=O)(=O)Cc1ccccc1C#N +Cc1nc2cc(NC(=O)CCNc3ccccc3C)ccc2o1 +Cc1cccc(NC(=O)NCC(=O)N(Cc2ccccc2)C(C)C)c1 +CCc1ccc(O)c(C(=O)N2CCCN(c3nc(C)cs3)CC2)c1 +CCC(=O)Nc1ccc(Cl)c(NCC(=O)Nc2cc(C)nn2C)c1 +CCOC(=O)NCC(C)(C)c1ccc(OC)c(OC)c1 +NC(=O)NCCC(=O)N1CCc2ccc(Cl)cc2C1 +CCc1ccc(S(=O)(=O)N2CCN(Cc3ccncc3)CC2)cc1 +Cc1cnc(-c2ccc(-n3ccnc3-c3cccnc3)cc2)nc1 +CC(C)Oc1ccc(Cc2nn3cnnc3n(CCO)c2=O)cc1 +Cc1cccc(C2(C(=O)NC(C)Cn3cccn3)CC2)c1 +CCc1cccc(C)c1NC(=O)CCC1C(=O)N=C(C)N=C1C +NC(=O)c1cccc(CNC(=O)c2scnc2C2CCCC2)c1 +Cc1nn2c(CNC(=O)c3ccccc3)nnc2c2ccccc12 +N#Cc1ccc(C(=O)N2CCN(Cc3cc4ccccn4n3)CC2)cc1 +CCC1(C)Nc2cc(F)ccc2N(CC(C)C#N)C1=O +COc1ccc(C(O)CNC(=O)CCc2c(C)[nH]c(=O)[nH]c2=O)cc1 +COc1ccnc(Cn2ncc(N3CCCC3)cc2=O)c1OC +O=C(NCc1cn(-c2ccccc2)nn1)c1ccc(F)cc1F +C=C(C)COc1cccc(C(=O)N(CC)C2COCC2O)c1 +CS(=O)c1ccc(CNC(=O)NC2CCCc3ccccc32)cc1 +COCc1ccc(C(=O)NCCS(=O)(=O)N2CCCC2)s1 +CSc1ccc(CNc2cccc(F)c2C#N)cc1 +Cc1nc(C(=O)NCCc2ccc(Cl)cc2)cs1 +COc1cccn(CCOc2ccc(N)c(C)c2)c1=O +O=C(NC1CCCC1)C1CN(C(=O)COc2ccccc2F)C1 +O=C(CCC1CCCO1)N1CCOCC1C1CC1 +O=S(=O)(NCc1ccccn1)c1ccc(Cl)cc1F +c1cc(CN2CC3COCC(C2)N3CC2CC2)co1 +NC(=O)c1nc(C(=O)N2CCN(c3ccccc3)CC2)cs1 +O=C(Cn1c(=O)c2cccn2c2ccccc21)N1CCOCC1 +Cc1nc2sc(C(C)C)nn2c(=O)c1CCO +CCCS(=O)(=O)Nc1cc(C#CCCO)ccc1C +O=C(COc1ccccc1)N1CCc2ncnc(NC3CC3)c2CC1 +COc1ccc(S(=O)(=O)NCC(O)c2sccc2C)c(C)c1 +Cc1cnn(C)c1C(=O)Nc1ccccc1-c1nc2ccccc2[nH]1 +CC(OC(=O)C(NC(=O)c1ccc(F)cc1)C(C)C)c1cccnc1 +CCNC(=O)c1ccc(S(=O)(=O)NC(C)(C)C)cc1 +CN(C)c1cccc(C(=O)Nc2ccc3[nH]c(C(F)F)nc3c2)c1 +CCCNC(=O)Nc1ccnn1Cc1ccccc1 +CCc1ccc2c(CN3CCN(CCOC)C(=O)C3)cc(=O)oc2c1 +Fc1cc(Br)ccc1CNc1cnn(-c2ncccn2)c1 +CC(C)c1nnc2n1CCN(C(=O)c1ccc(C(F)(F)F)nc1)C2 +Cc1cc(C)cc(NC(=O)CSc2nc(=O)[nH]cc2C)c1 +O=c1cc(C=Cc2ccc(F)cc2)ccn1CCCO +CCS(=O)(=O)N1CCN(C(=O)Nc2ccc(F)c(Cl)c2)CC1 +CCCN(C)S(=O)(=O)c1cc(OC)c(OC)cc1C +CC(=O)c1cccc(NC(=O)CNC(=O)c2ccc(C)s2)c1 +CCC(CC)C(=O)Nc1ccc(-c2nc[nH]n2)cc1 +O=c1[nH]c(CNCc2ccccc2)nc2ccccc12 +CC(NC(=O)c1ccc(-n2ccnn2)cc1)c1ccc2c(c1)CC(=O)N2 +CCN(CC(=O)NCc1sccc1C)CC(C)C#N +COc1cc(C(N)C(F)(F)F)cc(Br)c1O +CC1(C)Cc2cc(CN(CCC#N)CCC(F)(F)F)ccc2O1 +Cc1ccnn2c(C(N)c3ccccc3F)nnc12 +CCC(C#N)CCC(=O)NCc1ccc2c(c1)OCO2 +COC(=O)CSc1nnc(CSc2nc(C)cc(C)n2)o1 +CCN(CCC#N)S(=O)(=O)c1ccc(NC(C)=O)cc1 +CC1CCCCC1NC(=O)Cc1csc(NC(=O)C2CC2)n1 +Cc1ccc(-c2cc(C)nc(-n3ncc(C#N)c3N)n2)c(C)c1 +Cc1ccc(C(=O)OCCc2c(C)n[nH]c2C)c(C)c1 +CCCC1CN(C(=O)Nc2c(C)cccc2CC)CCO1 +CN(C(=O)Cn1ncc2c1-c1ccccc1OC2)c1ccccc1 +Cc1ccc(-n2ncc(C(=O)N(C)C)c2C(C)C)cc1 +CCc1nnc2ccc(-c3noc(CNC(=O)c4ccccc4)n3)cn12 +CC(C#N)CNC(=O)Nc1ccc2cnn(C(C)C)c2c1 +CCOc1ccc(-n2nnc(C(=O)NC(C)C)c2N)cc1 +Cc1cccc(NC(=O)COC(=O)COc2ccc3c(c2)CCC3)c1 +CS(=O)(=O)NCC(=O)N1CCN(S(C)(=O)=O)CC1 +CCc1noc(C2CCN(C(=O)c3ccc(C)s3)CC2)n1 +COCCNC(=O)c1nnc(Cc2cccc(Cl)c2)o1 +CCOC(=O)c1cc(S(=O)(=O)NCc2ccc(Cl)cc2)n[nH]1 +CN(Cc1cccnc1)C(=O)C1CCCN1S(C)(=O)=O +CC(C)CC(=O)NCc1ccc(C(=O)NC2CC2)cc1 +Cc1ccc(NC(=O)Nc2ccc(S(=O)(=O)C(F)F)cc2)cc1 +O=C(Nc1ccnc2ccnn12)C1CCN(CC(F)(F)F)CC1 +O=c1oc2cccnc2n1Cc1cc(F)ccc1F +CN(CC(=O)NCc1ccco1)S(=O)(=O)c1ccc(F)cc1 +Nn1ccc2nc3ccn(-c4ccccc4)c(=O)c3cc2c1=O +Cc1nnc(C(=O)NC(C)Cc2ccc(Br)cc2)s1 +COc1ccccc1Oc1ccc(NC(=O)NC(C)(C)CCO)cc1 +CC(C)CNS(=O)(=O)c1ccc(F)c(C(F)(F)F)c1 +COc1ccc(CC(=O)N(C)c2nc(C)cs2)cc1OC +COc1cc(C(=O)N(Cc2csc(C)n2)c2ccc(F)cc2)on1 +Cc1nc(CCNC(=O)N(CC2CCOC2)C2CC2)cs1 +CNC(=O)Cc1ccc(NCc2cnn(C)c2)cc1 +CCn1cnnc1CNS(=O)(=O)c1cc(OC)ccc1OC +CCOC(=O)c1sc(NC(=O)c2ccco2)cc1C +O=C(NCCCc1ccccc1)C1CC(=O)N(C2CCCCC2)C1 +CC(=O)Nc1ccc(SCC(=O)Nc2cccc(Cl)c2C)cc1 +Cc1cnc(C(=O)N2CCCCC2CNS(C)(=O)=O)cn1 +O=C(Cc1ccc[nH]1)N1CCN(c2ccccc2)CC1 +CCOC(=O)Nc1ccc(NC(C)c2nc(C(C)C)no2)cc1 +CCN(CC(C)C#N)S(=O)(=O)CCc1ccccn1 +CC1CCCN(c2ccc(Br)cn2)C1 +COCCNc1cc(Br)ccc1OC +CCc1cccc(C)c1NCC(=O)Nc1c(C)cccc1C +C=CCn1c(SCC(N)=O)nnc1-c1ccccc1 +Cc1ccc(C(=O)NCc2ccccc2CO)c(=O)[nH]1 +COC(=O)Cc1csc(NC(=O)N(C)Cc2ccc(C#N)cc2)n1 +CCN(Cc1ccccc1F)C(=O)c1csc(C(C)=O)c1 +CC(C)c1ccc(OCCNC(=O)Cc2ccon2)cc1 +CC1(NC(=O)c2ccc(OCC(N)=O)cc2)CCCC1 +COCCCNc1ncnc(Nc2ccc(C)cn2)c1N +Cc1nc(CN(C)C(=O)Nc2ccc(Cl)cc2F)cs1 +O=C(c1cccnc1)N1CC(c2n[nH]c3ncccc23)C1 +COc1ccc(CN(C)C(=O)Nc2cnccc2C)cc1C +O=C(Nc1ccc2nc(-c3ccco3)[nH]c2c1)c1cn2cccnc2n1 +COCc1cc(N(C)Cc2n[nH]c3c2CCCCC3)n2nccc2n1 +O=C(Nc1cccc(CNC(=O)c2ccco2)c1)c1cccc(F)c1 +CC(NC(=O)c1ccc[nH]c1=O)c1nc(-c2ccc(F)cc2)no1 +CC(c1ccco1)N(C)S(=O)(=O)c1cccc(C(F)(F)F)c1 +CCN(C(=O)NCc1ccnc(OC)c1)C(C)C(C)C +O=C(COCC1CCCO1)NC1CCCC1Oc1ccccc1 +N#Cc1cccc(N2CCCC3(CCC(=O)N(CC4CC4)C3)C2)n1 +Cc1cc(C)n(-c2ccc(CCNC(=O)C(C)(C)C)cc2)n1 +C#CCn1nc(CO)cc1-c1ccc2c(c1)CC(=O)N2C +O=S(=O)(NCCCc1ccccc1)c1ccccc1F +CC(C)(C(=O)Nc1cnn(CC(N)=O)c1)c1ccccc1F +N#CCn1ccc(NC(=O)c2cc(Br)ccc2Cl)n1 +CCC(C)NC(=O)C(C)Sc1nc(C)cs1 +N#Cc1ccccc1CN1CCC2(CC1)COC(=O)O2 +CC(=O)N1CCCC(c2cncc(Nc3ncccn3)n2)C1 +CC(C)C(C)(C#N)NC(=O)CSc1ccc(N)cc1 +Cc1ccc(CC(=O)N(C)C(C)c2cccc(Cl)c2)cn1 +CCOc1ccccc1C(=O)Nc1ccc(F)cc1N +COCC(O)CN(C)C(=O)CCc1nc(C)no1 +COc1ccccc1OC(C)C(=O)Nc1ccc(CC#N)cc1 +Cc1nccc(CNC(=O)COc2ccc(F)cc2Cl)n1 +CCCc1cc(C(=O)NC(C)c2c(C)noc2C)sc1C +Cc1cccc(-c2nnc(-c3csc(N4CCOCC4)n3)o2)n1 +O=C(c1cc(F)ccc1Br)N1Cc2ccccc2C1 +CC(C(=O)Nc1cccc2cn[nH]c12)n1cncn1 +Cc1nc2ncnn2c(Sc2nc(-c3cccs3)n[nH]2)c1C +CC(CC(=O)Oc1cccc(NC(=O)C2CC2)c1)c1ccccc1 +Cc1ccccc1NC(=O)c1ccc2[nH]nnc2c1 +Nc1cc(C(=O)NC2CCCNC2=O)ccc1Br +Cc1cc(Oc2ccc(=O)n(C)n2)nc(SCC(N)=O)n1 +c1cc(-c2noc(-c3ccc(OCC4CC4)cc3)n2)ccn1 +O=C(NCc1ccccc1)Nc1ccc(S(=O)(=O)C(F)F)cc1 +CC(=O)N1CCC(C(=O)N(C)Cc2ccco2)CC1 +Cc1nc(C(C)(C)C)sc1C(=O)NC(C)(C)C +CC(=O)Nc1ccc(SCC(=O)Nc2ccccc2F)nn1 +Oc1ccccc1-c1ccnc(SC(F)F)n1 +CCCCN(C)S(=O)(=O)N(C)C1CCCCNC1=O +CN(C(=O)c1cc[nH]n1)C1CCc2ccccc2C1 +CN(Cc1cccs1)C(=O)c1cc(F)ccc1N +CCN(CC(=O)OC)C(=O)Cn1c(C)csc1=O +Cc1ccc(S(=O)(=O)NCCC(=O)N2CCOCC2)cc1 +CS(=O)(=O)Nc1ccc2oc3ncccc3c(=O)c2c1 +CC(CNC(=O)NCc1cn(C)nc1C(F)(F)F)c1nccs1 +Nc1cccc(-c2nc3ccc(F)cc3n2CCO)c1 +CCS(=O)(=O)NCC#CCOc1cccnc1 +COc1cccc(C2CN(Cc3cccnc3C)CCO2)c1 +CCn1nc(C)cc1C(=O)Nc1nc(-c2ccccc2)cs1 +Cc1cn(-c2ccccc2Cl)nc1NC(=O)NC1CCCCC1O +CCc1ccsc1C(=O)NCCNC(=O)C(C)C +Cc1ccc(OCCCNC(=O)CC2(O)CCCCC2)cc1 +Cc1cc(NC(=O)CN2CCN(c3ccc4nncn4n3)CC2)no1 +COc1ccc(C(=O)Nc2nc(C3CC3)cs2)cc1OC +O=C(c1ccco1)N1CCN(Cc2nnnn2C2CC2)CC1 +O=S(=O)(Nc1ccccc1F)c1cccc(Cl)c1 +COC(=O)c1nnsc1NC(=O)c1cccc(Br)c1 +Cc1ccc(-c2nc(C(=O)N(C)CC(=O)N(C)C)cs2)c(C)c1 +O=C(Nc1ncc(Cl)cc1Cl)c1ccn(C(F)F)n1 +COc1ccccc1COC(=O)c1ccc(-n2ccnn2)cc1 +CCCN(CC1CC1)C(=O)Nc1ccncc1F +O=C(CCn1nnc2ccccc21)OCC(=O)c1ccc(Cl)cc1 +CN(CCC#N)C(=O)CSc1nc2ccccc2[nH]1 +O=C(NCCc1cccnc1)C12CC3CC(CC(C3)C1)C2 +Cc1noc2ncnc(N3CCC4(CC3)OCCO4)c12 +COc1ccc(C(=O)C2CCCCN2)cc1C(C)C +O=C(CCNC(=O)c1cc2ccoc2s1)NCc1cccs1 +Cc1cc(C)n(Cc2ccc(C(=O)NCc3ccccc3C)o2)n1 +O=S(=O)(NCc1ccco1)c1ccc(-c2csnn2)s1 +CCn1c(CNC(=O)N2CCOCC2)nnc1SC +COc1ccc(CNC(=O)NC2CCCN(S(C)(=O)=O)C2)cc1 +COc1cccc(C(=O)N2CCN(c3ccc(Cl)cc3)CC2)c1 +Cc1cc(C(=O)NCC(C)(C)c2ccncc2)oc1C +Cc1cccc(C(=O)NCCC(=O)NCC2CCCO2)c1 +COC(=O)c1ccccc1OC(=O)CCn1ccccc1=O +CCn1cc(Cl)c(C(=O)Nc2cccc(-c3ccno3)c2)n1 +COC(C)(C)c1noc(-c2csc(-c3ccccc3F)n2)n1 +Cc1ccc(F)cc1NC(=O)c1ccc(-n2cccn2)cc1 +CCC(C)NC(=O)C1CN(C(C)=O)c2ccccc2O1 +CCc1ccc(CN(C)C(=O)c2cc(C)on2)cc1 +COc1ccc(CCC(=O)N(C)c2cccc3ncccc23)cc1F +O=C1CN(C(=O)NCCc2ccc(F)c(Br)c2)CCN1 +CCCNC(=O)c1cccc(C(=O)N(C)C(C)c2ccco2)c1 +CCc1onc(C)c1NC(=O)NCC(C)Cn1nc(C)cc1C +Cc1nnc(COc2ccc(Br)c3ccncc23)o1 +Cc1nc2ccc(Cc3nc(C4CC4)nn3-c3ccccn3)cc2[nH]1 +CCC(c1cccnc1)N(C)C(=O)Nc1ccc(C)nc1C +Cc1nc2ccccn2c1C(=O)NCCCn1ncccc1=O +Cn1cc(C(=O)NCC#CCOc2ccc3c(c2)OCO3)nn1 +Cc1cc(NC(=O)C2(c3ccc(F)cc3F)CCCC2)nn1C +Cc1cc(C)cc(N(CC(=O)NCC(C)C)S(C)(=O)=O)c1 +CCNC(=O)CN(C)C(=O)CNC(=O)c1ccsc1 +Cn1cccc1C1CCCN1C(=O)NCc1ccccc1 +CC(=O)N1CCN(CCNS(=O)(=O)c2ccc(C)cc2)CC1 +COc1ccc(OCCNC(C#N)c2ccco2)cc1 +CC(C)COc1ncnc(NCCc2ccc(F)cc2)c1N +COC(=O)c1c(C)nc(C2CC2)nc1SCC(N)=O +Cc1cccc(NS(=O)(=O)c2ccc3c(c2)CC(=O)N3)c1C +O=C(Cc1c[nH]c2ccccc12)N1CCC(Nc2cccnc2)CC1 +CC(C)(C)C1CCCCC1NC(=O)c1c[nH]c2ccccc2c1=O +Cc1c(CCC(=O)NC(C)CNc2ccccc2)cnn1C +COc1c(C2CCCN2C(=O)c2cnc[nH]2)c(C)nn1C +COc1ccc(C(C)NC(=O)c2ccc3ncccc3c2)cc1 +Cc1nc(CNS(=O)(=O)c2cnn(C(F)F)c2C)no1 +COc1ccc(CNC(=O)c2ccc(C)nc2C)c(OC)c1OC +CCc1cc(-c2nc(-c3ccc(C#N)cn3)no2)sc1C +Cc1ccc(CC(=O)N(C)C(C)c2ccccc2Cl)cn1 +O=C(Cn1nc(-c2ccco2)oc1=O)c1ccc2c(c1)CCC2 +COC(=O)C(C)(C)NC(=O)CCNC(=O)c1ccc2ccccc2c1 +CCCn1c2c(=O)[nH]c(=O)n(C)c2n2c(-c3ccc(F)cc3)nnc12 +Cc1nc2ccccc2nc1NCCc1ccc(S(N)(=O)=O)cc1 +CNC(=O)c1ccc(S(=O)(=O)NC(C)C(C)C)cc1 +COCCn1c(C)cc(C(=O)CN2CC(C)OC(C)C2)c1C +COc1cc(N)ccc1NC(=O)c1ccc(C)s1 +O=C(NCCCCN1CCOCC1)NCc1ccccn1 +CC(Cn1cccn1)NC(=O)NC1CCCCC1 +CCOCCCNC(=O)c1oc2c(C)cccc2c1C +Cc1nc2cc(F)ccc2cc1C(=O)N1CCOC(C)C1 +CCCCN(CC)C(=O)c1cccc(S(C)(=O)=O)c1 +Cc1ccc(C(=O)Cn2nc3c(-c4nc(C)no4)cccn3c2=O)cc1 +CCS(=O)(=O)NCC1Cn2nnc(-c3ccsc3)c2CO1 +Cc1nc2nc(SCC(=O)NCCC(C)C)nn2c(C)c1C +Cc1ccc(C)c(OCC(=O)N(C)CCO)c1C +O=C(Cn1ccc(C(F)(F)F)n1)NCc1ccc2c(c1)OCCO2 +CC(Cc1ccsc1)NC(=O)Nc1cn[nH]c1 +COc1cc(CC(=O)Nc2cc(F)c(OC)cc2OC)ccc1C +O=C(c1ccccc1Br)N1CCCC1CCCO +O=C(NCCC(=O)N1CCCC1)c1ccc(Oc2ccccc2)cc1 +CC(C)n1c(SCc2nc3ccccc3c(=O)[nH]2)nnc1N(C)C +COc1ccc2nc(Cn3cnc4sc(C)cc4c3=O)[nH]c2c1 +CC1CCn2c(nc3cc(C(=O)N4CCOCC4)ccc32)C1 +O=C1COc2cc(C(=O)NCCc3ccco3)ccc2N1 +O=C(NCCCn1cccn1)c1cnc2n(c1=O)CCS2 +Cc1cccc(C)c1NCc1cc(F)c(F)c(F)c1 +Cc1ccc(C(=O)Nc2ccc(OCC(F)(F)F)cc2)o1 +COCCS(=O)(=O)Nc1ccc(N)cc1C(F)(F)F +O=C(Cc1ccccn1)c1ccc(Cl)c(Cl)c1 +CNC(=O)NCC(=O)Nc1ccc(OC2CCC2)c(F)c1 +Cc1cc(NC(=O)C2CCCCN2S(C)(=O)=O)c2ncccc2c1 +O=C(C1CCCO1)N1CCN(c2ccc(-n3cccc3)nn2)CC1 +Cc1ccc(NC(=O)c2cc(-c3cccnc3)on2)cc1F +N#CCc1c(-c2ccc3c(c2)CCCC3)cn[nH]c1=O +COc1cccc(-n2ccnc2SCC(O)CO)c1 +C=CCn1cnnc1SCC(=O)c1ccc2c(c1)CCCC(=O)N2 +Cc1ncsc1C(=O)NCCNC(=O)c1ccccc1Cl +O=C(Cc1ccc(Cl)c(Cl)c1)NCC(F)(F)F +COc1ccc(C(=O)NCC2Cc3cc(F)cc(F)c3O2)cc1 +CN(C(=O)NCc1ccco1)C(CO)C(C)(C)C +FC(F)(F)Oc1ccccc1CNc1cncnc1 +CCN(CCO)c1ncnc2sc(C)c(-c3ccc(F)cc3)c12 +COCC(C)NC(=O)c1ccc(OCC2CCCO2)cc1 +CCOc1ccccc1NC(=O)C1CC(=O)N(Cc2ccccc2)C1 +CN(CCO)C(=O)COc1ccccc1Br +COc1cc(C#N)ccc1OC(C)C(=O)NC1CCCCC1C +O=C1CC2C(=O)Nc3nc(N4CCCCC4)nc(c32)N1 +CC(C)c1nc2cc(NC(=O)c3[nH]nc4c3CCC4)ccc2n1C +CCCOc1cc2c(cc1OC)CCNC2c1nc[nH]n1 +N#Cc1ccc(N2CCC3(CCNC(=O)CC3)CC2)nc1 +CC(=O)c1ccc(Nc2ncnc(Nc3cc(C)on3)c2N)cc1 +CC(=O)c1ccc(NC(=O)NCCc2c(C)noc2C)cc1C +COc1c(O)c(Cl)cc2c1C(C1CC=CC1)NCC2 +Cc1ccc(Cl)cc1-c1cc(C#N)nn1CC#N +CC(C)(C)c1ncc2c(n1)CN(C(=O)Cn1nc3ccccc3n1)C2 +CSc1ccccc1C(=O)NCC(O)c1ccc2c(c1)CCO2 +CCSc1nc2ccsc2c(=O)n1C1CC1 +CC(=O)NC(C)C(=O)Nc1ccc(Br)cc1 +CC(=O)c1ccccc1OCCN1CCN(C(C)=O)CC1 +CCOCCCNC(=O)c1cc(Br)cn1C +O=C(NCC1CC=CCC1)Nc1nc(C2CC2)cs1 +NS(=O)(=O)CC1CCN(C(=O)c2cc3ccccc3s2)CC1 +CCSc1ccccc1C(=O)Nc1nc(C)c(C)s1 +CCN(Cc1ccccc1)C(=O)c1cnc2ccsc2c1 +O=C(C1CCC1)N(Cc1ccccn1)c1nc2ccccc2s1 +C=CCn1c2cc(C)oc2c2cnn(CC(=O)N(C)C)c(=O)c21 +Cc1[nH]c(=O)[nH]c(=O)c1CC(=O)N1CCCC(CCC(N)=O)C1 +O=C(CC1CCC(C(F)(F)F)CC1)NCCc1ccc[nH]1 +CSc1n[nH]c(NC(=O)c2cccnc2)c1C#N +COCc1cc(CNC(=O)c2c(C)cc(C)[nH]c2=O)n[nH]1 +N#Cc1cn(Cc2ccc(OC(F)F)cc2)c2ccccc2c1=O +CCOC(=O)c1nn(-c2ccccc2)cc1CN1CCOCC1CC +CC(C)(CNC(=O)N1CCOC(C(N)=O)C1)c1ccccc1 +CCOc1cc(C(=O)OCC(=O)NC)cc(Br)c1OC +Cc1ccc(OCc2cccc(C(=O)N3CCC3)c2)cn1 +CCCC1Nc2ccccc2N(C(CC)C(N)=O)C1=O +Cc1cc(=O)c(C(C)(C)O)nn1-c1ccc(F)c(Cl)c1 +Cc1ncc(CNC(=O)c2cnn(-c3cccc(Cl)c3)c2C)s1 +Cc1cccc2nc(-c3cccc(N)c3)c(CC#N)n12 +CC(NC(=O)NCc1ccccc1Cn1cccn1)C1CCCO1 +CC(C)C(=O)OCC(=O)c1ccc2c(c1)CC(C)N2S(C)(=O)=O +O=C1CN(c2ccccc2NC(=O)C2CCC(=O)N2)CCN1 +CCC(C)(NC(=O)C(C)Sc1ccccn1)c1nc(C)cs1 +NC(=O)c1ccc(NC(=O)COn2nnc3ccccc32)cc1 +Cc1cc(NC(=O)c2ccc3[nH]c(=O)c(=O)[nH]c3c2)c2ncccc2c1 +O=S(=O)(Nc1ccc(CCO)cc1)c1ccc2c(c1)COC2 +CS(=O)(=O)c1cccc(C(=O)N2CCC(C(N)=O)CC2)c1 +N#Cc1ccccc1OCc1ccc(C(=O)NCc2cccnc2)o1 +COC(=O)c1cc(Br)c(N)c(OC)c1 +CC(C)(CNC(=O)CCN1CCCC1=O)c1ccncc1 +CCOC(=O)C1CCCCN1C(=O)Cn1ccnc1 +Nc1cc(-c2ccc(Br)cc2F)n[nH]1 +CC(C)(C)c1nc(CN2CCOCC2C2CC2)no1 +CC(C)(CNC(=O)C1COCCO1)c1cccc(Cl)c1 +O=S(=O)(Nc1ccc2c(c1)OCO2)c1ccccc1Cl +Cc1cc(C(=O)Nc2cc(Cl)cc(Cl)c2O)on1 +CCC(C(=O)NCC(C)c1ccsc1)N1CCCC1=O +CCN(C(=O)NCC1CN2CCCCC2CO1)C(C)C(C)C +O=C(Cc1cccc(F)c1)N1CCn2c(Cn3cncn3)cnc2C1 +COc1cccc(CCC(=O)Oc2ccc3c(c2)CCC(=O)N3)c1 +COc1cc(F)c(C(=O)Nc2cccc3cn[nH]c23)cc1OC +COC(=O)c1cc2c(=O)n3cccc(C)c3nc2s1 +O=C(OCC1COc2ccccc2O1)c1cc2ccccc2oc1=O +Cc1cc(CNC(=O)CSc2ncccn2)no1 +COCc1nnc2sc(-c3cccc(Br)c3)nn12 +CN(C)S(=O)(=O)N1CCCC(CO)(Cc2cccc(Cl)c2)C1 +COc1ccc(NC(=O)CSc2nnnn2C)c(C)c1 +COc1cc(NC(=O)Cc2noc3ccccc23)ccc1NC(C)=O +CC(C)c1noc(CCNS(=O)(=O)c2ccc(F)cc2F)n1 +CCCC1(CNC(=O)c2c(C)oc3ncn(C)c(=O)c23)CCC1 +Cc1oc(=O)oc1CSc1nnc(C23CC4CC(CC(C4)C2)C3)o1 +Cc1csc(CCCNC(=O)c2cccc3ccc(C)nc23)n1 +CCc1nn2c(N)ncnc2c1-c1ccc(Cl)cc1 +CCCC(C)C(=O)Nc1ccc(-c2nc(C)cc(=O)[nH]2)cc1 +COC(=O)C1CCN(C(=O)c2cc(F)cc(F)c2)CC1 +CC(=O)Nc1cccc(NCC(=O)N2CCN(C(=O)C3CC3)CC2)c1 +O=S(=O)(c1cccnc1)N1CCC(c2nc(C3CC3)no2)C1 +NC(=O)C1CCC(NC(=O)c2ccccc2F)CC1 +CCOc1ccccc1NC(=O)c1ccc2c(c1)nnn2CC +COC(=O)C1CN(Cc2ccc(F)c(Cl)c2)CCO1 +CCCC(=O)Nc1cc(OC)c(OC)c(OC)c1 +Cc1ccc(C(=O)NCc2ccccc2Cn2cccn2)c(O)c1 +Cc1n[nH]c(C)c1CC(C)C(=O)N1CCN(c2ccc(O)cc2)CC1 +CCN(Cc1ccccc1NC(=O)N1CCOC(C)(C)C1)C(C)=O +COCCCC(=O)Nc1ccc(NC(=O)OC)cc1 +COc1cc(C(C#N)C(=O)C2CCCO2)ccc1C +CCc1ccc2c(CSc3nncn3C3CC3)cc(=O)oc2c1 +O=C(Nc1ccccc1C(F)(F)F)C1CN(S(=O)(=O)C2CC2)C1 +Cc1cc(C(=O)NCCn2cnnc2)c2ccc(C)c(C)c2n1 +NS(=O)(=O)c1cccc(NC(=O)CCCC2CCCCC2)c1 +c1cnc(NCCc2cccc3cccnc23)nc1 +O=C(c1ccoc1)N1CCN(c2ncc(Cl)cc2Cl)CC1 +CCOc1ccc2nc(NC(=O)c3ccn(C(C)C)n3)sc2c1 +COC(=O)c1cc(C)nc(Nc2ccc(NC(C)=O)cc2)n1 +C#CCOc1cccc(NC(=O)N(C)CCN2CCOCC2)c1 +CCc1[nH]nc(NS(=O)(=O)c2cccnc2)c1C +O=C(CCc1nc2ccccc2s1)OCC(=O)c1ccccc1 +Cc1cccc(NC(=O)C2CCCN(C(=O)c3ccc(F)cc3)C2)c1 +CN(C(=O)c1ccco1)c1ccccc1C(=O)C(C#N)c1ccccn1 +COc1ccc(F)cc1NC(=O)N(C)Cc1ccncc1 +C#CCS(=O)(=O)c1ccc(OCC)c(OCC)c1 +CCC(=O)NC(CC)Cn1nnc2ccccc2c1=O +CCN(Cc1ccc(C)cc1)Cc1cc(=O)n2nc(C)sc2n1 +Cc1cc(F)ccc1CCNC(=O)c1cnc(-c2ncccn2)s1 +CCOc1cccc(C(=O)NCC(=O)N2CCCc3ccccc32)c1 +CCn1cc(CNC(=O)c2ccc(C#N)cc2)cn1 +COc1cc(C)sc1C(=O)N1CCN(S(C)(=O)=O)CC1 +CCn1c(N)nc2cc(C(=O)NCCOc3ccccc3)cnc21 +Cc1noc(C)c1S(=O)(=O)N1CCN(C(C)C(=O)N(C)C)CC1 +CC(=O)NCCNC(=O)c1sc(-c2cccs2)nc1C +Cc1ccc(NC(=O)Nc2cccnc2)cc1Br +CC(CNC(=O)C1COc2ccc(F)cc2C1)N1CCOCC1C +CC(Cn1ccnc1)NC(=O)c1cc2c(s1)CCCCC2 +CCOc1ccc(NC(=O)c2nn(-c3ccccc3)nc2C)cc1 +CC(CO)(NC(=O)Nc1cccc(CN2CCCCC2=O)c1)C1CC1 +N#Cc1ccc(NC(=O)N(CCO)Cc2cccnc2)cc1 +CC1(C)OC(=O)C(C(=O)Cc2cc(F)c(F)cc2F)C(=O)O1 +Cc1ccc(C(=O)OCc2nc(-c3ccc(Cl)cc3)no2)cn1 +CC(=O)c1cccc(Nc2ncnc(N3CCCCC3C)c2N)c1 +COc1ccc(NC(=O)C2CC(=O)N(Cc3ccccn3)C2)cc1 +O=C(NC1CCCCC1n1cccn1)c1scnc1C1CC1 +CCc1noc(CC)c1CNC(=O)C(C)NC(=O)C(C)(C)C +O=C(Nc1cccc(NC(=O)C2CC2)c1)c1ccc2ccccc2n1 +O=C(NCc1cccs1)Nc1cccc2cnccc12 +CC(Sc1ccccc1O)C(=O)NC1CCCC1 +COc1ccc(C(O)C(C)NC(=O)C2(CC(C)C)CCC2)cc1 +CCCN(CC1CCCCC1)C(=O)c1cnn(-c2ccncc2)c1C +Cc1c(C(=O)N2CCC(C)(C)C2)cnn1-c1ccncc1 +CC(C)OCCCNC(=O)c1cnn(-c2ccc(Cl)cc2)c1 +CC(=O)N(CCc1ccccc1)CC(=O)Nc1ccnn1C +C=CCOC(=O)CNC(=O)c1ccccc1Br +COc1ncc(Cl)c(N2CCC(c3nncn3C3CC3)CC2)n1 +O=S(=O)(CC1CCCO1)N(CCO)C1CCCCC1 +O=C(NCCCn1cccn1)C1CCCCN1C(=O)c1cccs1 +Cc1ccccc1CN1CCN(S(=O)(=O)c2ccc(F)cc2)CC1 +CCn1cc(N)c(-c2ccc(S(C)(=O)=O)cc2)n1 +Cc1nc2c(cc1C(=O)NCC1CC1C)c(C)nn2C +Cc1cc(CNC(=O)c2ccc(O)nc2)ccc1F +Cc1ccc(F)cc1S(=O)(=O)Nc1cccc2c1OCCO2 +CCOC(=O)CCN(C)S(=O)(=O)c1c(C)n[nH]c1C +COc1ccc(-c2c(C)sc(NC(C)=O)c2C#N)cc1 +O=C(NCCCN1CCCC1=O)c1cn(CC2CCCCC2)nn1 +CC(C)(C)c1ccc2oc(-c3cc(N)[nH]n3)nc2c1 +CC(C)Cc1nnc(NC(=O)N(C)Cc2ccccn2)s1 +Cc1ccc(-n2nnc(C(=O)Nc3cccc(F)c3)c2C)cc1 +Cn1nnc2c1C(COCC1CC1)CN(C(=O)c1ccccc1F)C2 +Cn1ccnc1-c1nc2c([nH]1)CC(C)(C)CNC2=O +CN(Cc1c(F)cccc1Cl)c1cccc(N)c1 +Cc1ccc(-n2ncc(C(=O)NCCc3ccccc3)c2C)cc1 +CC(C)Sc1ccccc1C(=O)Nc1cccn(C)c1=O +CC(C)Cn1cc(C(=O)N2CCCC2C(=O)N2CCN(C)CC2)cn1 +Nc1ccc(Sc2ncnc3ccccc23)c(Cl)c1 +Cc1cccnc1C(NC(=O)c1cnc(-c2cccnc2)nc1)C1CC1 +CC(=O)NCCNC(=O)NCc1cnc(C)s1 +COCc1noc(-c2ccc(N3CCCCC3COC)nc2)n1 +CC(C)Oc1cccc2c1CCN(Cc1ccccc1)C2=O +CCOc1cc(C)c(C)cc1S(=O)(=O)NCCN1CCOCC1 +Cc1ccc(S(C)(=O)=O)cc1NCC(=O)NC(C)(C#N)C1CC1 +Cc1ccc(NC(=O)CC2C(=O)Nc3nc(C)nn32)c(Cl)c1 +CC(=O)Nc1ccccc1OCC(=O)NCc1ccccc1Cl +N#CC(C(=O)Cn1ccccc1=O)c1nc(-c2ccccc2)cs1 +O=C(NCc1cccc(Cl)c1)c1scnc1C1CC1 +CC1CCCC(C)N(C(=O)NCc2cn(-c3ccccc3)nn2)C1 +CCC(=O)Oc1ccc(C(=O)Nc2cc(C)on2)cc1OC +CCCn1c(C)nnc1SC(C)C(=O)c1ccc(OC)cc1 +COc1cccc(C(=O)Nc2sc3c(c2C#N)CCC3)c1 +CC(=O)N(C)c1ccc(NC(=O)c2ccco2)cc1 +CC(=O)N1CCN(C(=O)c2c3c(nc4ccccc24)CCC3)CC1 +O=C(Nc1cnn(-c2ccccc2Cl)c1)c1scnc1C1CC1 +COC(=O)NCCC(=O)NC(c1ccccc1F)C1CCCC1 +Cc1cccc(CNS(=O)(=O)c2cc(F)ccc2F)n1 +COc1cccc(C(=O)N2CCN(Cc3nc(C)no3)CC2)c1F +CCNC(=O)CCS(=O)(=O)c1nnc(-c2cccs2)n1CC +COCC(C)NC(=O)N1CCN(Cc2csc(C)n2)CC1 +O=C(NC1CCSc2ccc(F)cc21)c1ccc(F)cc1Cl +CCNC(=O)C1CCCN(C(=O)c2cnc3ccc(C)cn23)C1 +c1ccc(-c2cnc(C3CCOCC3)c3cnncc23)cc1 +CCc1nc(N2CCN(C(C)=O)CC2)c2c(n1)c(C)nn2C +CN1CCn2c(cnc2C(=O)NCc2ccccc2)C1 +CCC1(CNC(=O)NCC2CN3CCCCC3CO2)CC1 +CC(=O)N1CCc2ccc(NC(=O)Nc3cccs3)cc2C1 +COc1cccc(C(=O)Nc2ccc(OCC(F)(F)F)nc2)c1F +O=C(CCCc1cn[nH]c1)N1CCC(F)(F)CC1 +O=C(Nc1ccc(OC(F)F)c(Cl)c1)c1ccc[nH]c1=O +CCOc1ccccc1-c1ccc(CO)c(=O)n1C(C)C +Cc1nc2ccccc2n1CCNC(=O)c1cccnc1N1CCCC1 +Cc1cc(C)cc(NCC(O)c2ccc(F)c(N)c2)c1 +O=C(Nc1cccc(NC(=O)C2CCCO2)c1)c1ccco1 +CCc1cccc(CC)c1NC(=O)c1cncc(Br)c1 +Cc1ccc(NC(=O)c2cc(N3CCCC3=O)ccc2Cl)cc1 +O=C(NCC#CCOc1cccc(Br)c1)C1CC1 +CCOC(=O)N(C)c1ccc(NCc2c(C)nn(C)c2C)cc1 +Cn1cccc1CN(C(=O)c1cc(=O)c2ccccc2o1)C1CC1 +CC(C)(C)NC(=O)c1cccc(NC(=O)NCC(=O)NC2CC2)c1 +NC(=O)c1cccc(CNS(=O)(=O)c2ccc(F)c(F)c2)c1 +CCn1cc(CN(C)Cc2ccc(C(F)(F)F)cc2F)cn1 +CC(C)COc1nc(C2CCCO2)nc(NC(C)C)c1N +N#Cc1c(NC(=O)c2cc(Cl)ccn2)sc2c1CCC2 +Cc1cc(NC(=O)c2cccnc2)nn1Cc1ccc(F)cc1 +Cc1cc(N2CCOCC2)c(N)c(=O)n1C1CCCCC1 +COc1ccc2c(c1OC)CCNC2c1cncc(F)c1 +CCC(O)C(=O)N1CCc2c(nc(C)nc2N(C)C)C1 +O=C(Nc1ccc(NC(=O)C2CCCCC2)c(O)c1)c1ccco1 +CCC(O)(CC)CNC(=O)Nc1cccc(OC)c1 +CCC(CCO)NC(=O)Nc1cc(NC(=O)C(C)C)ccc1C +CCCNC(=O)C(C)N(CCC)c1ccccc1N +COC(=O)c1cc(C)ccc1OCC(=O)Nc1ccccc1 +O=C(CSc1ccc(-c2ccccc2)nn1)NC1CC1 +CCOC(=O)c1nc2sc(C3CCC3)nn2c1C#N +O=C(NCc1ccncc1)Nc1cccc(C(=O)NC2CC2)c1 +COC(=O)C(C)CN(C)C(=O)c1nccnc1N +Cc1nc(NC(=O)CC2C=CCC2)sc1SCC(N)=O +O=C(CCc1ccccc1)NC1CCCCNC1=O +O=C(CCC1CCCO1)Nc1ccc(-n2cnc3ccccc32)cc1 +COCCNC(=O)Nc1nnc(-c2ccccc2Cl)o1 +O=C(CCc1ccccc1)Nc1cccc(-c2cc[nH]n2)c1 +O=C(Nc1ccc2c3c(cccc13)CC2)c1cnccn1 +Cc1c(C(=O)NC2CCCCC2OCCC(C)C)cnn1C +CCOC(=O)C(C)NC(=O)c1cccc(NC(C)=O)c1 +Cc1cc(C(=O)NC2CCCCCC2)ccc1NS(C)(=O)=O +CCC1(C)CC(=O)c2cc(Br)cc(N)c2O1 +COCCNS(=O)(=O)c1cc(OC)ccc1OC +COc1ccc(S(=O)(=O)NCc2cc(C)oc2C)cc1C +COc1ccc(Cn2ncc3ccccc3c2=O)cc1F +Cc1ccc(C2CC(=O)NCc3nc4sccn4c32)cc1C +CC(C)S(=O)(=O)NCc1cccnc1-n1cccn1 +Cn1cccc1C(=O)NCCNC(=O)C1CCCc2ccccc21 +N#CC1(CN2CCN(c3ccc(F)cc3)CC2)CCCC1 +CNc1ncnc(Oc2cccc3cccnc23)c1N +CC(=O)Nc1ccc(C)c(NC(C)C(=O)Nc2c(C)nn(C)c2C)c1 +Cc1ccc(C(=O)OCC(=O)Nc2ccc3c(c2)CCC3)s1 +CC(C)c1ccc(-n2ccnc2S(C)(=O)=O)cc1 +CCN(CC(=O)NC(C)C)C(=O)c1sc(C)cc1OC(F)F +CCC(=O)N1CCCN(C(=O)CCCc2ccccc2)CC1 +COCC(C)NC(=O)CSc1nnc(-c2ccoc2C)o1 +CS(=O)(=O)c1ccc(S(C)(=O)=O)c(S(C)(=O)=O)c1 +COC(=O)c1ccc(OCC(=O)c2ccc(C)cc2)c(OC)c1 +CC(=O)Nc1ccc(SCC(=O)NCc2ccccc2)cc1 +COc1ccc(-c2cc(CC(=O)NC(C)(C)C)no2)cc1OC +CN(Cc1ccncc1)C(=O)NCCc1ccccc1F +CC(NC(=O)Nc1ccccc1F)c1cccnc1 +COc1ccc(C(=O)N2CCC(C)CC2C)cc1OC(F)F +O=C(NCc1ccccc1F)c1cc(Cl)ccn1 +O=C(NCCCC(=O)N1CCCC1C1CCCC1)c1cccs1 +Cc1cc(C(=O)Nc2cccc(N3CCOC3=O)c2)sc1C +COC(=O)C(NC(=O)Nc1cccn2c(C)nnc12)c1ccccc1 +Cc1cccc(N2CCN(C(=O)c3ccc(C(N)=O)cc3)CC2)c1C +CN1C(=O)Cc2cc(NC(=O)Nc3ccc(C(F)(F)F)cc3)ccc21 +CCC(C)NC(=O)Nc1cc2ccc(OC)cc2n1C +COC(=O)CC1CN(Cc2cc(F)cc(C(F)(F)F)c2)CCO1 +Cc1ncc(C=Cc2nc(CC(=O)NC3CCCC3)no2)s1 +CCOc1ccc(Cl)c(C(=O)NC(C)C2CCCO2)n1 +COc1ccc(Cl)cc1S(=O)(=O)N1CCC(C)CC1 +CCCCCNC(=O)CCc1c(C)c2c(C)nn(C)c2[nH]c1=O +Cc1nc(-c2ccco2)nc2sc(C(=O)N(C)C)c(C)c12 +CCC(=O)N1CCCC(n2nnn(-c3ccccc3)c2=O)C1 +Cc1c(CC(=O)NCc2ccncc2)c(=O)oc2cc(O)ccc12 +CC(CNC(=O)c1cccc(-n2cnnc2)n1)N(C)c1ccccc1 +Cc1cc(C)c(S(=O)(=O)N(C)CC(=O)N2CCOCC2)c(C)c1 +O=S(=O)(c1ccc(Cl)cc1)N1CCOC(c2ccccc2)C1 +CCCCNC(=O)c1onc(S(=O)(=O)CCC)c1N +O=C1CCN(C(=O)c2ccc(OCC(F)F)nc2)c2ccccc2N1 +C=CCNS(=O)(=O)c1ccc(NC(=O)c2ccccc2OC)cc1 +COCCNS(=O)(=O)c1cc(C)c(OC)cc1C +CCC(C)Sc1ccc(S(=O)(=O)N2CCCCC2)cn1 +CCC(=O)Nc1ccc(NC(=O)C2CCOC2)cc1 +CC(C)(C)NC(=O)CSc1ncc(C#N)c(N)n1 +Cc1csc(C(=O)N2CC(c3nc(-c4ccc[nH]c4=O)no3)C2)c1 +CCOC(=O)C(CC)N1C(=O)COc2ccc(CO)cc21 +Cc1ccc(C(=O)NCCCS(=O)(=O)c2ccccc2)c(=O)[nH]1 +COc1cc(OC)c(NC(=O)N2CC(C)OC(C)C2)cc1Cl +NC(=O)c1ccc(CNC(=O)c2cccnc2N2CCOCC2)cc1 +CCCCC(=O)Nc1n[nH]c(-c2ccc(OC)cc2OC)n1 +CCOc1cccc(NS(=O)(=O)c2cccc(C(=O)N(C)C)c2)c1 +CSc1ccsc1C(=O)N1CCN(C(=O)CO)CC1 +CC(C)n1cnnc1SCC1=NS(=O)(=O)c2ccccc2N1 +CC(CCCO)NC(=O)N1CCC(Nc2ccccc2)C1 +CC1CN(Cc2cnc3cnccn23)C(C)(C)CO1 +CCOc1c(Cl)cc(C(=O)N2CCCC(C)C2)cc1OC +COc1ccccc1C(C)N(C)C(=O)c1ncc[nH]1 +COc1ccccc1OC(=O)CCn1ccccc1=O +O=S(=O)(c1ccccc1)C1CC2C=CC1CCC21OCCO1 +Nc1ccc(S(=O)(=O)NCCc2cccs2)cn1 +OCCn1nc(-c2ccc(Br)cc2)c2c1CCNC2 +CS(=O)(=O)Nc1cccc(CNC(=O)c2ccc3[nH]nnc3c2)c1 +Cc1ccc(C#N)cc1NC(=O)NCc1ccccn1 +COc1ccc(-c2noc(CN3CCN(C(=O)C(C)C)CC3)n2)cc1 +Cc1cccn2cc(CC(=O)NCc3ccccc3N3CCCC3)nc12 +Cc1cc(C)n2nc(C)c(C(=O)NCC3(C(N)=O)CCOCC3)c2n1 +CC(=O)c1ccc(NCC(=O)Nc2ccc(C(=O)N(C)C)cc2)cc1 +CCOc1ccc(C(=O)NC(C)c2ccc(S(N)(=O)=O)cc2)cc1 +Cc1nnc2n1CCN(Cc1ccc(Cl)cc1F)C2 +COCCN(Cc1ccsc1)C(=O)c1ccc(Cl)cc1Cl +CCCCCCNC(=O)c1cnc(-c2ccncc2)nc1N +COc1cc2c(cc1OC)C(=O)N(Cc1ccccc1)CC2 +COC(=O)C(CNC(=O)c1occc1C)Oc1ccc(F)cc1 +CCOc1cccc(CNC(=O)c2cn3cccc(C)c3n2)c1 +COc1ccc(CNC(=O)CCSc2ccccn2)cn1 +CN(C)S(=O)(=O)c1cccc(Cn2nnc(-c3ccccc3)n2)c1 +CC1CCN(S(=O)(=O)c2ccc(N)cc2)CC1 +O=C(Nc1ccccc1F)N1CC(c2nc(-c3ccccn3)no2)C1 +CC1CCCC(OC(=O)c2csc(-c3ncccn3)n2)C1 +COc1cc(CCC(=O)N(C)Cc2ccccc2)cc(N)c1OC +COc1ccccc1C(CNC(=O)Cc1cccc(C)c1)OC +CC(C)N(C)C(=O)NC1CCN(C(=O)c2ccccc2F)CC1 +COCCn1cc(NC(=O)C2CCN(c3ncccn3)CC2)cn1 +CC1CN(S(=O)(=O)c2cc(Br)ccc2N)CCCO1 +Cc1sc(NC(=O)N2CCOCC2)c(C#N)c1C +C#CCN1CCC(C(=O)NC(C)c2ccc(-c3cccnc3)cc2)CC1 +CN(C)C(=O)COCC1CN(Cc2ccccn2)Cc2ccnn2C1 +COC(=O)c1ccccc1NC(=O)CNC(=O)c1ccccc1Cl +Cc1csc(SCC(=O)Nc2cc(N)ccc2C)n1 +C=C(C)CN1C(=O)C(c2ccccc2)Oc2ccc(N)nc21 +CC(=O)NC(C(=O)NCCc1c[nH]c2ccccc12)C(C)C +CC(CO)NC(=O)CCCNC(=O)c1ccc(F)cc1F +Cn1c(CNC(CO)c2cc(F)c(F)c(F)c2)nnc1C1CC1 +CCOC(=O)c1c(Cl)c2ccccc2n(CC)c1=O +Cc1nc(C(C)N(C)C(=O)c2cncnc2)c(C)s1 +NC(=O)C1CC(=O)N(Cc2ccccc2C(F)(F)F)C1 +NC(=O)c1cc(-c2csc(NC3CC3)n2)ccc1O +Cc1ccncc1NC(=O)NCc1cc(Br)ccc1F +O=C(NCC(O)COCC1CC1)Nc1cccc(Cl)c1 +C=CCOC(=O)C1=C(C)Nc2nc(SCC)nn2C1c1ccco1 +Cc1n[nH]c(C2CN(CC(=O)NC3(C#N)CCCC3)CCO2)n1 +Cc1cc(C)c(O)c(-c2cc(C(=O)Nc3cccnc3)[nH]n2)c1 +Cc1oc2ncn(C)c(=O)c2c1C(=O)Nc1ccccc1O +C=CCNC(=O)c1nnc2n(c1=O)CCN2c1ccc(OCC)cc1 +Cc1ccc(NC(=O)c2cccn2Cc2noc(C3CC3)n2)cc1C +Cc1ccc2cc3c(nc2c1C)OC(=O)N(Cc1ccco1)C3 +O=C(COc1ccccc1)NCC1CC(=O)N(c2ccccc2)C1 +Nc1ccccc1-n1c(CCO)nc2cccnc21 +COCCN(Cc1ccco1)S(=O)(=O)c1ccc(F)cc1 +c1ccc2c(c1)CN(CCCN1CCOCC1)CC2n1cccn1 +CCN(CC)c1cc(NC(C)=O)c(Cl)cc1N +CC1c2ccsc2CCN1c1cc(N)cc(F)c1 +CC(=O)Nc1scc(-c2ccccc2)c1C(=O)N1CCCCCC1 +Cc1cc(N2CCN(C(=O)COCC3CCCO3)CC2)nc(C)n1 +O=C(NCc1ccccc1)N1CCCC1c1nc(-c2cnccn2)n[nH]1 +CC(C)N(C)C(=O)COc1ccc2ccc(=O)oc2c1 +O=C1NCCN2CCN(C(=O)Cn3ccc(=O)c4ccccc43)CC12 +CC(C)(CNC(=O)c1cncn1-c1ccccc1)C(N)=O +CCc1onc(C)c1NC(=O)NCC(C)CC(C)O +CCc1cc(Br)cc2c1OC(C)CC(=O)N2 +CN(C(=O)c1ccnc(OC2CCC2)c1)C1CCC(CO)CC1 +CC1(C)Cc2c(sc3[nH]c(=O)n(Cc4ccccc4)c(=O)c23)CO1 +Cc1cccc2c1NC(c1ccc(Cl)cc1Cl)NC2=O +O=C(CSc1ccccc1Cl)NCCOc1cccnc1 +CCOC(=O)C(CC)n1cc(CO)c2cc(C)ccc21 +CN(Cc1ccccc1Br)C(=O)c1nccnc1N +CCN(CC)C(=O)c1c(C)nc(N)nc1-c1ccccc1OC(C)C +CCC1CN(Cc2nc(C)c3ccccc3n2)CCN1CC(C)O +O=C(NCc1cccs1)c1cc2c(cn1)OCC2 +COC(=O)C(C)(C)NC(=O)c1ccc(OCc2ccccc2)nc1 +CC(C)(C)c1csc(Cn2cnc(C3CCC3)cc2=O)n1 +Cc1cc(NCc2nc(CC(C)C)no2)ccc1C(=O)NC(C)C +O=C(c1cc(Cl)c2c(c1)OCO2)N1CCCCCC1 +CC(C)N1CC(C(=O)Nc2cc(C(F)(F)F)ccc2Cl)CC1=O +COc1cc(C)ccc1C(=O)Cn1cc(Br)cn1 +Cc1nc2ccc(Cl)cn2c1-c1nc(C2CCOC2)no1 +CC(C)(O)CN1CCN(c2ccc(F)cc2)CC1 +Cc1cc(CN(C)C(=O)C(C)(C)c2ccc3c(c2)OCCO3)no1 +O=C(CCc1nc2ccccc2[nH]c1=O)NCCN1CCNC1=O +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)NCC1(c2ccccc2)CC1 +Cc1cccc(-n2cnnc2CN2CCOCC2)c1 +O=C(CN1CCOCC1)Nc1ccnn1Cc1cccc(Cl)c1 +COC(=O)Cc1ccc(Oc2ccnc(C#N)c2)cc1 +CCCCC(=O)Nc1ccc(Br)c(C)n1 +CCn1cc(C(=O)Nc2ccc(C)c(F)c2)c(=O)c2ccc(C)nc21 +CC(=O)Nc1ccc(CC(=O)N2c3ccccc3CC2C)cc1 +CCCOc1ccc2c(c1)C(c1ccc(C)nc1)NCC2 +CNC(=O)Cc1csc(NC(=O)c2nc(-c3cnccn3)no2)n1 +Cc1onc(-c2ccccc2)c1C(=O)N(C)CCC#N +CS(=O)(=O)c1ccc(OCC(=O)N2CCCc3ccccc32)cc1 +O=C(NCCCc1nc2ccccc2[nH]1)c1cccc2ncccc12 +CC1CC(Nc2ccc(F)c(NC(=O)Cc3ccccc3)c2)C(=O)O1 +CCCn1cc(C(=O)OCC)c(=O)c2c3c(ccc21)C=CS3(=O)=O +O=C(NC1CCC(O)CC1)c1ccc(NC(=O)c2cccs2)cc1 +Cc1nn(C)c(C)c1NC(=O)CNc1c(F)cccc1N1CCCC1 +CCc1noc(CC)c1CNS(=O)(=O)N1CCCC(C)C1 +Cc1ccc(-c2nnco2)cc1NC(=O)C1Cc2cc(F)ccc2O1 +CC(C)C(NC(N)=O)C(=O)NCC(c1ccccc1)c1ccccc1 +O=C(CCC(=O)N1CC(=O)Nc2ccccc21)Nc1cccnc1 +CCN1CCC2(CN(C(=O)c3cccnc3)CC2C)C1=O +Cn1cc(CNC(=O)CCC(=O)c2ccc(F)c(F)c2)cn1 +O=C(Nc1cc(N2CCCC2)ncn1)c1cccc(Br)c1 +CCNC(=O)c1cn(C2CCCCC2)cc(C(=O)NCC(C)C)c1=O +O=C(NCc1cccnc1)Nc1cc(F)ccc1Cl +O=C(c1cccnc1)N1CC2CCC(C1)N(C(=O)Cc1ccccc1)C2 +CCNC(=O)C1CCCN(C(=O)c2ccc(NC(=O)C(C)C)cc2)C1 +O=C(NCc1cn(-c2ccccc2)nn1)Nc1cc(F)c(F)c(F)c1 +CCCc1nnc(N2CC(Oc3ccccc3F)C2)o1 +CCOC(=O)c1csc(NC(=O)CCc2ccco2)n1 +O=C(c1cnc(C2CCCO2)s1)N(Cc1ccccc1F)C1CC1 +O=C(NCCCn1cccn1)C1CCC(=O)N(CC2CCCCC2)C1 +Cc1nnc(NC(=O)c2cn(C)c3ccccc23)s1 +c1ccc(-c2nc(NCc3ccnc(OC4CCOC4)c3)no2)cc1 +COCCN1CCN(C(=O)C2CC(=O)N(CCC(C)C)C2)CC1 +N#CCc1c(-c2ccc(F)cc2)nc2sccn12 +O=C(CSc1ccccn1)Nc1nnc(C2CCCCC2)s1 +Cc1cccc(CNC(=O)CCNS(=O)(=O)c2cccnc2)c1 +Cn1cc(-c2ncc(C(=O)NCCC3CCCC3)s2)cn1 +N#CC(C(=O)CC1=CCCCC1)c1nc2ccccc2[nH]1 +CCCCNC(=O)C(O)c1ccc(O)c(Cl)c1 +Nc1ccc2nc(CC(=O)Nc3cccnc3)ccc2c1 +O=C(CN1CCOCC1C1CC1)N1CCCCCC1 +CN(C)c1nccc(N2CCOC3CN(C(=O)N4CCCC4)CC32)n1 +Nc1ncnc2sc3c(c12)CCN(C(=O)c1cc2ccccc2[nH]1)C3 +CCOC(=O)c1c(C)c(CCC(=O)NC(C)C)c(C)n1C +O=S(=O)(Nc1ccc(C2=NCCO2)cc1)c1ccc(Cl)cc1 +COc1ccc(OC)c(CN(C)C(=O)c2c(C)oc(C)c2C)c1 +Cc1cc(N2CCC(C(=O)N(C)Cc3ccccc3)C2=O)ccc1F +Cc1c(CNC(=O)Nc2cc(F)ccc2N2CCCCC2)cnn1C +Cc1ccccc1NCCC(=O)NCc1sccc1C +O=C(NCCc1ccccn1)c1ccc(-n2cccc2)cc1 +O=C(NCc1csc(N2CCOCC2)n1)c1cn2ccsc2n1 +CCn1ccnc1CN1CCCN(C(=O)c2sccc2OC)CC1 +CSc1cccc(NC(=O)CN2CCOCC2C2CC2)c1 +Cc1nn(C(C)C)c(C)c1NC(=O)C1(n2cnnn2)CCCCC1 +Cc1noc(C)c1S(=O)(=O)NCc1ccccc1Cn1cccn1 +COCc1cccc(C(=O)NC(C)C(O)c2ccc(OC)cc2)c1 +Cc1cccc(N2C(=O)c3cccnc3C2CC(=O)NC2CCCC2)c1 +Cc1cc(NCC(=O)NC(C)C(C)C)ccc1-n1cnnn1 +O=C(Cc1noc2ccccc12)Nc1ccc(F)cc1 +Cc1nc(C)n(CC2CN(Cc3nnc(C(C)(C)C)o3)CCO2)n1 +CC1CC(N2CC=C(c3ccccc3Cl)CC2)C(=O)O1 +CN(Cc1ncnn1C)C(=O)C12CC3CC(CC(C3)C1)C2 +CCOCc1ccc(NC(=O)CNC(=O)NC)cc1 +NC(=O)CCCNC(=O)c1[nH]c2ccccc2c1Cl +Cc1nc(C(C)(C)NC(=O)c2ccc(Cl)cc2)sc1C +O=C(c1ccnnc1)N1CCC2OC(COCC3CC3)CCC21 +CC(C)NC(=O)CN1CCN(CC(=O)NC(C)C(C)C)CC1 +Cc1cc(C2CCCN2C(=O)CCCc2c[nH]c3ccccc23)no1 +O=C(CCCOCc1ccccc1)N1CCCC(n2cncn2)C1 +CN(Cc1ccccc1)S(=O)(=O)c1ccc(Cl)cc1N +O=c1[nH]nc(CN2CCCC2Cc2ccccc2Cl)[nH]1 +Cc1ccc(SCCC(=O)NCC(=O)NC2CC2)cc1 +C#CCN1CCN(Cc2cc(=O)oc3cc(CC)c(Cl)cc23)CC1 +COc1ccccc1OCC(O)CNc1cccc(C)c1 +c1ccc(C2COC3CCC(n4nnc5ccccc54)N32)cc1 +Cc1ccn(-c2ccc(N3CC4CCCC4C3)nn2)n1 +CCc1nnc(N2CCN(C(=O)c3ccco3)CC2)o1 +CC(C)C(CNC(=O)c1ccccc1Cl)N1CCOCC1 +COc1ccc(S(=O)(=O)NCC#Cc2ccccc2OC)cc1C +O=C(NCCc1ccco1)c1csc(-c2cccs2)n1 +Cc1ncc(-c2ccc(NC(=O)C(c3ccccc3)N(C)C)cc2)o1 +Oc1ccccc1NCc1ccc2c(c1)OCCO2 +CCCCN(CC(N)=O)C(=O)c1cc(Br)c[nH]1 +COc1ccc(CCNc2ccc(C#N)cc2)cc1 +Cn1cnnc1C1CCCN(S(=O)(=O)N2CCOCC2)C1 +C=CCOC(=O)c1ccc(-c2ccc(N)cc2Br)o1 +CCn1c(-c2cc(C)ccc2C)ccc(CO)c1=O +COc1cc2c(cc1OC)C(=O)N1CCCC1C(=O)N2 +CC(C)c1nnc(NC(=O)CCCCNC(N)=O)s1 +O=C(NCCc1ccncc1)c1cccc2ccoc12 +O=C(CCNC(=O)c1ccccc1F)NCc1cn2c(n1)SCC2 +O=C(CNc1n[nH]c(=O)[nH]c1=O)NCc1ccco1 +Cc1cc(NC(=O)CS(=O)(=O)c2ccc(Cl)cc2)n(C)n1 +CC1c2ccsc2CCN1S(=O)(=O)c1ccc(C#N)cc1 +COc1ccc(C2CCN(S(=O)(=O)c3ccc(C#N)cc3)C2)cc1 +COc1cc(OC)c(-c2cn[nH]c(=O)c2N)cc1OC +CC(=O)Nc1cc(NCc2nc3ccccc3n2C(C)C)ccc1F +Cc1ccc(NC(=O)NCC2(O)CCCC2)cc1C +COCCC1(O)CCN(C(=O)CCc2ccccn2)CC1C +COCCNC(=O)c1cc2c(s1)-c1cc(C)sc1CC2 +COc1ccc(N2CCN(c3ccccc3)CC2)n2nc(N)nc12 +O=C(CCc1ccc(OC(F)F)cc1)N1CCCC1c1ccncc1 +CCn1nnc2c(N3CC(C(=O)N4CCCCC4)C3)ncnc21 +CC1CN(C(=O)Nc2ccccc2C(C)C)CC(C)O1 +CCC(=O)NCC1CCN(C(=O)NC(C)(C)C)CC1 +Cc1ccc(S(=O)(=O)n2nc(C)c(CCC#N)c2C)cc1 +Cc1ccccc1COC(=O)C(N)c1ccccc1 +Cn1cc(Cl)c(C(=O)Nc2nc3ccc(Cl)cc3s2)n1 +Cc1ccncc1NC(=O)NCc1ccc(OCC(C)C)cc1 +C=C1C2(C(=O)Nc3cccc(C)n3)CCC(C2)C1(C)C +Nc1nc2cccc(N3CCc4ccccc4C3)n2n1 +CCc1ccc(-c2nccn2CC2CC(=O)N(C(C)C)C2)o1 +N#CCCCS(=O)(=O)c1ccc(Br)cn1 +Cc1cc(NS(C)(=O)=O)ccc1N1CCCC1=O +CC(C)(C)c1nn(-c2ccccn2)c2c1C(CC#N)CCC2 +Cc1ccsc1CN(C)C(=O)c1ccc(=O)[nH]c1 +O=C(Nc1cccnc1)c1ccccc1OCc1cscn1 +O=C(Cn1nc2ccccn2c1=O)Nc1nncs1 +CCOCC(=O)NCC(c1ccccc1Cl)N1CCOCC1 +Cc1cc(CNCCc2ccc(F)cc2)c(C)s1 +CC(C)CC(=O)Nc1ccc(NC(=O)c2ccccn2)cc1 +NS(=O)(=O)NC1CCN(c2c(F)cccc2F)C1 +CC(C)c1noc(CCC(=O)NC(C2CC2)C2CC2)n1 +CCCNC(=O)COc1cccc(-c2nc(CC)no2)c1 +CCCC(C(=O)NCC1(C(N)=O)CCOCC1)c1ccccc1 +Cc1nn(C)c(C)c1CC(=O)Nc1ccc(Cl)cc1F +C=CCn1c(SCc2nnc(C)o2)nnc1-c1ccccc1 +CCCS(=O)(=O)Nc1cc(C(C)C)nn1C(C)C +C#CCNC(=O)CSc1c(C)c(C)cc(C)c1C +CCOC(=O)C1CCN(C(=O)c2cnc3ccc(C)cn23)CC1 +CC(C)COCCNC(=O)NC1CCN(c2ccccc2)CC1 +CCc1ccccc1N(C)S(=O)(=O)c1cc(C(=O)OC)n(C)c1 +Cc1cc(Br)ccc1-c1nnc2ccc(N)cn12 +CC(=O)c1ccc2c(c1)nc(-c1ccncc1)n2C +CC1CN(CCC(O)c2ccc3c(c2)OCO3)CC(C)O1 +CC(=O)Nc1cccc2c1N(S(=O)(=O)c1cn(C)c(C)n1)CCC2 +Cc1cccc(NC(=O)c2csc(-c3ccco3)n2)c1C(N)=O +CC(=O)N1CCN(S(=O)(=O)c2ccc(CC(C)C)cc2)CC1 +CN(Cc1ccccc1)Cc1cc(-c2ccccc2)cn2nnnc12 +COc1ccc2c(c1)C(c1cc(=O)cc[nH]1)NCC2 +CC1CN(C(=O)NCCc2ccccc2F)CC(C)O1 +Cc1nc(C(C)(C)C)[nH]c(=O)c1C(=O)Nc1cccc(Cl)c1 +CC(=O)c1ccc(Nc2ncnc(NCC3CCCO3)c2N)cc1 +CCN(CC)C(=O)COc1cccc(NC(=O)c2ccccc2)c1 +C#CCOc1ccc(C(C)=O)cc1NC(=O)OC(C)(C)C +Cc1cccc(N(CCC(N)=O)C(=O)Cc2ccc(F)cc2F)c1 +O=C(NCc1ncc[nH]1)Nc1cccc(NC(=O)c2ccccc2)c1 +Nc1ncc(-c2ccccc2OCc2ccccc2)cn1 +CC1(C)Cc2c(sc(NC(=O)NCCO)c2C#N)CO1 +Cc1cc(C(=O)NCCCc2scnc2C)c2ccc(F)cc2n1 +Cc1nc(C2CC3CCN(C(=O)Cc4ccccn4)CC3O2)no1 +COc1ccc(NC(=O)N(C)C2CCCCCC2)cn1 +O=C(c1cccc(-c2ccoc2)c1)N1CCC2(CCCC2)C1 +CC(=O)NC1CCCN(c2ncnc3c2cnn3CCO)C1 +Cc1nn(-c2ccccc2)c(C)c1CNC(=O)C1CCC(=O)N1 +O=C(NCc1ccccc1)NCc1nnnn1C1CCCCC1 +CC(C)NC(=O)Nc1cccc(C(=O)N2CCOCC2(C)C)c1 +CCN(CC)C(=O)c1ccc(C)c(NC(=O)Nc2ccccc2)c1 +CCC(CC)CNC(=O)C(N)c1ccc(O)c(F)c1 +Cc1csc(N2CCCN(Cc3nc4c(s3)CCC4)CC2)n1 +COc1ccc2c(=O)cc(C(=O)NC3CC3)oc2c1 +CC1OCCN(C(=O)c2cccnc2OCC(F)F)C1C +Cc1ccc(CNc2cccc(NC(=O)C3CC3)c2)s1 +CNS(=O)(=O)c1cccc(CNC(=O)C2CC=CCC2)c1 +CC(C)CCC(C)(O)CNC(=O)NCc1cccnc1 +COc1cccc(C(=O)Nc2cnn(C(C)C)c2)c1F +CCN(CC)C(=O)NC(c1cccc(OC)c1OC)c1nccn1C +C=CC=c1c(=CC)oc2c(NCc3ccccc3)ncnc12 +COc1cc(OC)cc(C(=O)N(C)Cc2ccc(OC)c(F)c2)c1 +COc1cc(-c2cscc2N)cc(OC)c1OC +Cc1sc2nc(CSc3cc(C#N)ccn3)nc(N)c2c1C +O=C(CCC1CCCC1)N1CCN(Cc2ccccc2)c2ncccc21 +O=C(Nc1ccc(NCCO)nc1)c1cccnc1 +COC(=O)c1ccsc1NC(=O)Cc1ccccc1 +COc1ccc(C2CC(=O)c3cc(N)ccc3O2)cc1OC +Fc1ccccc1CCNCc1nc2c(s1)CCCC2 +CCc1ccc(S(=O)(=O)Nc2cc(N)ccc2C)cc1 +O=C(NCCc1ccc2c(c1)OCO2)c1ccc(O)c(Cl)c1 +O=C(NCCc1nc(-c2cccnc2)no1)c1cc2sccc2[nH]1 +COc1cccc(C(=O)Nc2ccccc2C(=O)NCC(C)C)c1 +CN(C(=O)c1cccnc1OCC(F)F)C1CCC(C)(C)CC1 +O=C(CC1COC2CN(c3ncccn3)CC12)Nc1cnccn1 +C=CCNc1nnc(-c2ccc(Cl)cc2O)s1 +CCC(O)CN1CCN(C(=O)CCc2c(C)nn(C)c2C)CC1 +C=CCNC(=O)c1cccc(S(=O)(=O)Nc2ccccc2CC)c1 +Cc1n[nH]c(SCC(=O)N(Cc2cccs2)C2CC2)n1 +CC(=O)N1Cc2ccccc2CC1C(=O)NCCNc1ncccn1 +CC(Cn1nc2c(cc1=O)CCCC2)NC(=O)c1ccccc1F +Cc1cc(OCC(=O)Nc2ccc(F)cc2F)c(C#N)c(C)n1 +O=C(NCCS(=O)(=O)c1ccccc1)c1scnc1C1CC1 +O=C(c1nc2c(s1)CCCN2C(=O)c1ccncc1)N1CCCC1 +CCOC(=O)CN(CC)C(=O)c1ccc(C(C)(C)C)cc1 +COc1ccc(-c2nc(C#N)c(NCc3ccccc3)o2)cc1OC +COc1ccc(-c2nnc3c(C)cc(N)cn23)cc1OC +O=C(C1CC=CCC1)N1CCN(c2nccc(C(F)(F)F)n2)CC1 +Cn1nc(C2CCC2)cc1NC(=O)c1cccc(OCC(F)F)n1 +CCOC1CC1C(=O)Nc1cnn(CCOC)c1 +CCOc1ccc(Oc2cc(CNC(=O)c3ccco3)ccn2)cc1 +Cc1ccc(NC(=O)COc2cc(F)ccc2N)cc1 +CN(C)c1cccc(C(=O)NCC(=O)N2CCc3ncccc3C2)c1 +COc1ccc2c(c1)S(=O)(=O)N=C(NCC1CCCO1)N2 +O=C(CCCn1cccc1)N1CCN(c2cccc(Cl)c2)CC1 +Cc1cc(NC(=O)Cc2ccc(Cl)cc2Cl)no1 +CCOC(=O)CC(C)CNC(=O)N1Cc2ccccc2N(C)CC1C +Cc1cc2c(=O)n(Cc3noc4c3CCCC4)cnc2s1 +NC(=O)CCCNC(=O)Nc1ccc(F)c(F)c1F +CC(C)OCCCNC(=O)c1cc(-c2ccc(Cl)cc2)n[nH]1 +O=C(NCc1ccc(Br)cc1Cl)C1CCCO1 +Cc1ccc(=NS(=O)(=O)c2ccc(C#N)c(C(F)(F)F)c2)[nH]c1 +COC(=O)c1cccc(NCC(O)c2ccc(F)cc2)c1 +CC(C)CCOC(C)C(=O)Nc1ccc(C#N)cc1 +CC(=O)N1CCCN(C(=O)NCC(C)Cn2nc(C)cc2C)CC1 +Nc1cc(-c2cccs2)nn(Cc2ccccc2Cl)c1=O +Cc1n[nH]c(C)c1CC(=O)N(Cc1ccncc1)C1CC1 +CNC(=O)N1CCN(C(=O)Cc2cccc(F)c2)CC1 +COc1cc(CNC(=O)N2CCCC(C(F)(F)F)C2)ccn1 +COc1ccc(NC(=O)NCCNC(=O)C2CC2)cc1 +COCCCNC(=O)Cc1cccn1-c1ccc(F)cc1 +COc1ccc2c(c1)N1C(=O)c3ccccc3C1c1cccn1-2 +CS(=O)(=O)NC1CCN(C(=O)NCc2ccc(C#N)cc2)CC1 +CN(Cc1ccccc1)C(=O)COC(=O)c1ccc(Cl)cc1N +COCc1ccccc1CNC(=O)c1sc(C)cc1OC +COCCCC1CCCN(C(=O)c2cnc(-c3ccccn3)nc2)C1 +Cc1ccn2c(-c3ccccc3Cl)nnc2c1N +CCc1nc(NC(=O)COc2ccc3ccc(=O)oc3c2)sc1C +N#Cc1cc(Nc2nc3c(s2)CCCC3)ccn1 +CN1C(=O)CN(Cc2cc(Cl)ccc2F)C(=O)c2ccccc21 +CC(=O)N1CCN(C(C)C(=O)NCc2ccc(Cl)cc2)CC1 +N#Cc1ccsc1NC(=O)Cn1cc(C(F)(F)F)ccc1=O +CCS(=O)(=O)c1ccccc1C(=O)N1CCC(CC(N)=O)CC1 +CCc1noc(CC)c1CNC(=O)C(C)Cc1c(C)nn(C)c1C +CC(C)COc1ccc(-c2ccc(CC#N)c(=O)n2C)cc1 +COc1ccc(C(C)(O)CNc2ccncn2)cc1 +CCN(CCO)C(=O)C1CCN(c2ccc(Cl)cn2)CC1 +Cn1cc(C(=O)N2CCC(Cc3ccc(F)cc3)CC2)ccc1=O +CCSc1nnc(NC(=O)Cn2nc(C)cc2C)s1 +O=C1CC(c2ccco2)Cc2[nH]c(=O)c(C(=O)Nc3ccccc3)cc21 +CC1CCCN(C(=O)NC2CCN(c3ccc(C#N)cn3)CC2)C1 +CC(=O)Nc1nc2c(s1)CN(Cc1cc(F)cc(F)c1)CC2 +CN(C)c1cc(C(=O)Nc2cnc(N(C)C)nc2)c2ccccc2n1 +CCCn1c(C)cc(-c2csc(NC(=O)C3CCC3)n2)c1C +COc1ccc(COc2nnc3ccccn23)cc1C#N +COc1cc(NC(=O)c2cnccn2)ccc1N1CCCC1=O +CC(C)COn1c(SC(C)C(N)=O)nc2ccccc2c1=O +CS(=O)(=O)NCCNC(=O)c1cc(N)ccc1Cl +Oc1cccc(CCNc2cnc3ccccc3n2)c1 +O=C(Nc1ccc(OCC2CCOCC2)cc1)N1CCCC1CO +Cc1ccncc1NC(=O)N(CC(C)O)C1CCCCC1 +CCc1ccc(CN(C)C(=O)CNC(=O)c2cccc(Cl)c2)cc1 +O=C(Nc1ccc(N2CCCC2)nc1)c1cc(F)cc(F)c1 +CC(C)Cn1nccc1NC(=O)Cn1cnc2ccccc2c1=O +Cn1ccnc1Sc1ncc(C(=O)Nc2nc[nH]n2)cc1Cl +COc1cc(C)c(Cl)c(C)c1C(O)C(=O)N(C)C +O=c1cc(-c2cccnc2)nc(Nc2ccccc2)[nH]1 +Cc1ccc(C(=O)Nc2cc3c(cc2Cl)OCCO3)cn1 +CC(C)CCN(C(=O)C(C)Sc1ccccn1)C1CC1 +C#CCNc1ccc(C(=O)Nc2ccc(OCC)cc2)cc1 +O=C(COc1ccccc1)N1CCc2c(c(CO)nn2CC2CC2)C1 +Cc1cc(C)cc(CN2CCc3ccc(N)cc32)c1 +CC(=O)c1nnn(Cc2ccc(Br)cc2)c1C +O=C(CNC(=O)c1ccccc1)Nc1nc(-c2ccccn2)cs1 +Nc1cccc(-c2ccc(NCc3ccccc3)nc2)c1 +CCOCC(O)CN1CCN(C(=O)c2cc3ccccc3[nH]2)CC1 +Cn1cnc2cc(OC(=O)Cn3cnc4ccccc43)ccc21 +CN(C)S(=O)(=O)NCCc1csc(-c2ccncc2)n1 +Cc1c(C(=O)NCC(O)c2cccs2)c(=O)oc2ccccc12 +O=C(Nc1ccn(-c2ncccc2Cl)n1)c1ccc2c(c1)CCO2 +COC(=O)CNC(=O)c1nnn(Cc2ccc(C)cc2)c1OC +Cc1ccc(N(C)C(=O)Cc2c(C)nn(C)c2C)c(C)c1 +Cc1ccsc1C(=O)Nc1ccccc1C(=O)N1CCC(C)CC1 +CCOC(=O)N1CCN(C(=O)Nc2ccc3oc(C)cc3c2)CC1 +Cc1ccccc1C(=O)NC(CC(C)C)C(=O)NCCO +CCc1nc(CNCC(OC)c2ccccc2)cs1 +Cc1ccccc1NC(=O)COC(=O)c1ccc(Cl)c(N)c1 +CN1CCCC2(CCN(C(=O)CCn3cnc4ccccc43)C2)C1=O +COc1ccc2c(c1)c(=O)c(C(=O)Nc1nnc(C)s1)cn2C +O=C1CCN(C(=O)c2ccc(-c3cscn3)cc2)CCN1 +O=C(NCc1ccccc1)c1cc2ccccc2c(=O)[nH]1 +COCC1CN(S(=O)(=O)c2ccccc2)Cc2ccnn2C1 +O=C(CCc1nnc(-c2ccccc2)o1)NCCC1=CCCCC1 +COCCNc1nnc(S(=O)(=O)Cc2cc(C)cc(C)c2)s1 +O=C(CCCSc1nnnn1-c1ccccc1)Nc1ccccc1 +C=CCNC(=O)CNC(=O)C12CC3CC(CC(C3)C1)C2 +Cc1nc(CC(=O)NC(c2ccc(F)cc2)C2CCCO2)cs1 +O=C(CSc1ccccn1)Nc1ccc(F)cc1F +COc1ccc2[nH]cc(CC(=O)NCC(C)Oc3ccccc3)c2c1 +CC(C)OCC(=O)N(C)Cc1nc2ccccc2[nH]1 +Cc1c(-c2ccccc2)sc2ncnc(NCCCO)c12 +Cc1oc(C)c(C(=O)NC2CCN(c3ncccn3)CC2)c1C +CCc1ccc2nc(NC(=O)Cc3c(C)nc(C)[nH]c3=O)sc2c1 +Cc1cnc(NCc2ccccc2OCC(=O)N(C)C)s1 +Cc1ccc(C(=O)N2CCOCC2)cc1NC(=O)c1cnccn1 +O=C(c1ccco1)N1CCN(Cc2nnnn2Cc2ccco2)CC1 +CCCSc1nnc(N2CCCCC2)n1CC1CCCO1 +Cc1ccc(CC(=O)N2CCCCC2CC(N)=O)cc1 +O=C(Nc1cccc(C(F)(F)F)c1)c1cnn(-c2ccccc2)c1 +CC(C)N(C)S(=O)(=O)NCc1ccc(Br)cc1 +Cc1occc1-c1nnc(SCC(=O)C(C)(C)C)n1C +O=C(CCCc1c[nH]c2ccccc12)Nc1nc[nH]n1 +CCC(=O)N1CCCN(C(=O)NCCc2ccccc2F)CC1 +C#Cc1cccc(NC(=O)NC(CC(=O)OC)c2cccs2)c1 +COCCC(=O)C(C#N)c1ccc(OC)c(F)c1 +Cc1cc(C(=O)Nc2cccc(C(N)=O)c2C)on1 +COc1ccc2nc(C(=O)NC3CCCCC3)sc2c1 +CCN(CC)C(=O)CCC(=O)C(C#N)c1nc2ccccc2[nH]1 +O=C(c1n[nH]c2ccccc12)N1CCN(Cc2ccccc2)CC1 +COc1ccc(CC(=O)N2c3ccccc3CC2C(N)=O)cc1OC +O=c1oc(-c2c(F)cccc2F)nn1-c1cc(C(F)(F)F)ccn1 +NC(=O)c1cccc(CNC(=O)N2CCN(c3ccccc3)CC2)c1 +CCC(CCO)NC(=O)NCC(C)(C)c1ccc2c(c1)OCCO2 +CCCN(CC(=O)OCC)C(=O)c1sccc1N +CCOc1c(OC)ccc2c1CCNC2c1ccnnc1 +O=C(C1CC=CC1)N1CCCn2c(CN3CCOCC3)nnc2C1 +NC(=O)CCCNC(=O)c1cccc(C(F)(F)F)c1 +COc1cccc(CNc2ccc3c(c2)C(=O)NC3)c1 +CCCCC(=O)N(C)C1(C(=O)OC)CCCCC1 +COc1ccc(Br)cc1CN(C)C(=O)c1cccnc1 +Cc1noc(C)c1CCCNC(=O)NC1(c2cccc(F)c2)CC1 +CC(=O)Nc1cc(C)c(S(=O)(=O)Nc2ccccc2F)c(C)c1 +CCS(=O)(=O)N1CCOC2C(Oc3ccccn3)CCC21 +N#Cc1cccc(OCCCC(=O)Nc2cccc(N)c2)c1 +Cc1cc(C)n2ncc(-c3noc(CSc4ccccc4)n3)c2n1 +OCCn1ncc2c(NCCc3ccc4c(c3)OCO4)ncnc21 +Cn1ccnc1SCC(=O)N1CCCCC1C(N)=O +CCCCc1nc(CN2CCN(c3cccc(O)c3)CC2)no1 +Cn1cc(C(=O)Nc2cccc(NC(N)=O)c2)c(C(F)(F)F)n1 +Cc1ccc2ncnc(OCc3cc(=O)n4ccc(C)cc4n3)c2c1 +NS(=O)(=O)c1ccc(-c2ccc(C(=O)N3CCCCC3)o2)cc1 +CCn1nc(C)c(CCNC(=O)Nc2cc(C)ccc2C)c1C +CC(C)(C)c1ncc2c(n1)CN(C(=O)CCCn1cnnn1)C2 +CN(C)C(=O)CNC(=O)c1cc(NC(=O)c2ccccc2)n(C)n1 +Cc1nc(CN2CCCC(c3nc4ccccc4o3)C2)cs1 +CCCCn1c(SCC(=O)N2CCCC2)nc2cn(C)nc2c1=O +Cc1cccc(-n2nnc(C(=O)NCc3ccccc3)c2N)c1 +COc1c(F)cccc1C(N)C(=O)NCC(C)C +N#CCCN1CCN(S(=O)(=O)CCc2ccccc2)CC1 +Cc1cccc(CNS(=O)(=O)c2ccc(C(C)(C)C)cc2)n1 +CCOC(=O)c1cnn(C(=O)c2ccc3ncccc3c2)c1N +CC(C)Oc1ccc(CNC(=O)c2cc(F)cc3[nH]cnc23)cc1 +CCOC(=O)COn1c(C)c(C(C)=O)c2c3nonc3ccc21 +Cc1ccc(C(N)=O)cc1S(=O)(=O)N1CCCCC1 +O=c1c(-c2cccc(Cl)c2)c[nH]n1-c1ccccc1 +CCN1CCN(Cc2ccc(C(=O)NC(C)C)cc2)C(=O)C1=O +O=C(c1cnccn1)N1CC(c2n[nH]c3ncccc23)C1 +COc1ccc(NC(=O)c2cc3ccccc3[nH]c2=O)cn1 +COc1ccc(-c2ncc3c(n2)CN(C(=O)OC(C)(C)C)CC3)cc1 +Cc1cccc(Cn2nc(C)nc2C2CCOCC2)c1 +CCCCN(C)C(=O)c1onc(C(=O)OC)c1N +C#Cc1cccc(N(CC)Cc2noc(C3CC3)n2)c1 +Cc1cc(C)c(NC(=O)CNc2nc3ccccc3o2)c(C)c1 +COCCN1CCN(C(=O)c2cccc(C(F)(F)F)c2)CC1 +CCCc1nc(C(C)(C)NC(=O)c2cc(-c3ccccc3)no2)no1 +CC(=O)NC1(C(=O)NC2CCCCC2)CCCCC1 +Cc1ccccc1-n1cnc(C(=O)N2CCC(C)CC2)n1 +COc1c(O)c(Cl)cc2c1C(C1CC1(C)C)NCC2 +COc1ccc(NC(=O)c2ccc(OC(F)F)c(OC)c2)cc1 +COCCOCc1nc(C)nn1-c1ccc(F)cc1 +Cc1csc(C(C)CNC(=O)Nc2ncnn2C)n1 +O=C(CCc1nc(-c2ccccc2Cl)no1)Nc1nccs1 +CC1CCC(C#N)(N2CCN(S(C)(=O)=O)CC2)CC1 +CCOc1cccc(C(=O)N2CCC(NS(C)(=O)=O)CC2)c1 +CC(C)(C)OC(=O)N1CCc2nnc(CO)n2CC1 +Cc1nc2cc(-c3cc(C#N)nn3-c3ccccc3)ccc2n1C +Cc1cc(NC(=O)CNC(C)(C)c2ccccc2)on1 +O=C(NCc1ccc(F)cc1)c1ccc(-n2cncn2)cc1 +COCCNC(=O)NCc1ccc(Cn2cnc3ccccc32)cc1 +COc1cc(C#N)ccc1OCc1nnnn1-c1ccccc1 +Cc1ccc(OC(C)C(=O)Nc2ccccn2)c(C)c1 +COc1cc(NC(=O)C2CC=CCC2)ccc1N1CCCC1=O +CN(C)C(=O)CCc1ccc(NC(=O)c2ccccc2)cc1 +Cc1ccoc1C(=O)N1CCN(Cc2c(C)noc2C)CC1 +COc1cccc(-c2nnc(SCC(=O)C(C)(C)C)o2)c1 +CCOC(=O)c1nn(Cc2ccc(F)cc2F)c(N)c1C +O=C(CC1CCCC1)Nc1cccnc1N1CCOCC1 +CC1CN(C(=O)c2ccc3c(c2)CCC3)CCC1(O)C1CCOCC1 +Cc1csc(CSc2nnc(C3CC3)s2)n1 +O=C(NCC1(Cc2ccccc2)CCC1)N(CCO)C1CC1 +Cc1noc(C)c1C(C)NC(=O)c1cnn(C(C)C)c1C(F)(F)F +CCCc1nc2cccnc2n1C1CCN(C(=O)c2ccsc2)C1 +O=C(NCCN1CCOCC1)c1cc2ccccc2cc1O +Cc1cc(C)cc(OCc2noc(CN3CCOCC3C3CC3)n2)c1 +Cc1cc(C)c(NC(=O)CNC(=O)NCc2sccc2C)c(C)c1 +CCc1nc(CNc2ccccc2Oc2ncccc2C#N)no1 +Cc1cc(C(=O)OC(C)C(=O)NC(C)(C)C)c(C)o1 +CCC(C)CN(C)C(=O)COc1ccc(C#N)cc1 +O=C(Cc1cc2ccccc2[nH]c1=O)NC(c1ccccc1)C1CCC1 +O=C(NCCNC(=O)c1ccn2ccsc12)NC1CCCCC1 +Cn1c(=O)c2c(ncn2CC(=O)N2CCc3ccccc32)n(C)c1=O +Cc1nn(C)c(C)c1CNC(=O)Nc1csc2ccccc12 +CCCOC1CCCN(C(=O)c2ccccc2Cl)C1 +CN(C)C(=O)c1cc(NC(=O)N(C)CCC#N)ccc1F +Cc1nc(SCC(=O)Nc2cccc(F)c2)nc(C)c1C +N#CCCCCOC(=O)c1cc(N)c(F)cc1F +O=S(=O)(Nc1cccc(O)c1)c1ccc(Cl)cc1 +CC1CCCN(C(=O)CSc2nnnn2C2CCOCC2)C1 +CSc1nc(C)c(CCC(=O)OCC(F)(F)F)c(=O)[nH]1 +c1ccc(OCCSc2nnnn2C2CCCC2)cc1 +COc1c(Cl)cc(S(=O)(=O)N2CCCCC2)cc1Cl +O=C(Cc1ccc2c(c1)CCCC2)NCc1cn2ccccc2n1 +COCCn1cc(NC(=O)NC(C)C2CC2)ccc1=O +O=C(Nc1ccc2c(c1)COC2)c1csc2c1CCCC2 +CC(C)c1ncc(C(=O)N2CCOC(c3ccc(F)cc3)C2)c(=O)[nH]1 +COCCOn1nnc2ccc(S(=O)(=O)N3CCOCC3)cc21 +O=C(Nn1cnc2ccccc21)N1CCN(CCc2ccccc2)CC1 +O=C(c1ccc(C(F)(F)F)cc1)N(Cc1cccs1)C1CC1 +Cc1cccc(OC(=O)C2CCCN2C(=O)Cc2cccs2)c1 +N#Cc1ccc(NCc2ccccc2-n2ccnc2)nc1 +O=C(COc1ccc(F)cc1F)N1CCNCC1 +O=C(NCc1ccccc1Cn1cncn1)c1cccc(F)c1 +CN(C(=O)C1CC=CCC1)c1ccc(S(C)(=O)=O)cc1 +CCC(=O)NCCNS(=O)(=O)c1ccccc1 +Cn1c(CCC(N)=O)nnc1SCc1ccc(Cl)cc1Cl +Cc1ccc(S(=O)(=O)N2C(=O)CCC2C(=O)N2CCCC2)cc1 +CC(=O)Nc1ccc(F)c(C(=O)NC(C)c2ccc(F)cc2F)c1 +COc1cccc(-c2cc(C(=O)NCCCN3CCOCC3)on2)c1 +COc1ccc(N(C)C(=O)Cc2cc(C)ccc2C)cn1 +Cc1cccc(CCCOC(=O)c2cccc(S(C)(=O)=O)c2)n1 +O=C(Nc1cccc(F)c1)c1cnc(C2CCCO2)s1 +OCC(O)C(O)C(O)C(O)C(O)c1nc2ccccc2[nH]1 +COC(=O)c1ccsc1NC(=O)COCC1CC1 +COC(=O)C(O)CNC(=O)c1ccccc1C(F)(F)F +CCOC(=O)c1c(C)c(C)c(C)c(C(=O)OCC)c1O +COC(=O)CCSc1nncn1-c1cccc(Cl)c1 +C#CCNS(=O)(=O)c1cccc(C(=O)N(C)C2(C#N)CCC2)c1 +O=C(OCCNc1ncccn1)c1csc(-c2ccccc2F)n1 +CC(=O)NC(c1ccccc1C(F)(F)F)C(F)(F)F +CNC(=O)C1CCN(C(=O)c2nc(C)n(-c3ccc(F)cc3)n2)CC1 +CCCCN(CC)S(=O)(=O)c1cccc(C(C)=O)c1 +O=C(Cc1ccc[nH]1)NC1CCc2cc(Br)ccc21 +Cc1nnc(NC(=O)c2sc3ccc(F)cc3c2C)s1 +CCOC(=O)CN(C)S(=O)(=O)c1cc(F)ccc1F +CN(Cc1cc(C(C)(C)C)n[nH]1)C(=O)c1ccc(-n2cnnc2)cc1 +COc1ccc(OC)c(CN(CCO)C(=O)C2CC=CC2)c1 +COc1cc2ccnc(C(C)=O)c2c(OC)c1OC +CN(c1ccccc1)c1ccccc1C(=O)NCCC(N)=O +COc1cccc(-c2n[nH]cc2C(=O)NCc2sc(C)nc2C)c1 +COCCCN(C)C(=O)CNC(=O)c1cc(C)oc1C +CCCNC(=O)CSc1ccc(-c2cccs2)nn1 +Cc1ocnc1C(=O)N1CCC(O)c2ccccc2C1 +NS(=O)(=O)c1cc(-c2nc(-c3ccsc3)no2)co1 +CC(C)(C)n1cc(CNc2ccc3c(c2)COC3)cn1 +CC(NC(N)=O)C(=O)NCCc1cccc(Cl)c1Cl +CC1(C)CN(C(=O)CCn2cncn2)CC1(C)O +CCCNc1nc(-c2[nH]c(C)c(C(=O)OC)c2C)cs1 +CC(C)(C)C(=O)CSc1nncn1-c1ccccc1 +CC(=O)N1c2ccccc2CC1C(=O)N(C(C)C)C1CCOCC1 +CC1(C)COC2(C=C(C(O)c3ccccc3)OCC2)OC1 +CCOC(=O)Sc1ncnc2nc3n(c12)CCCCC3 +COc1cccc(-c2noc(Cn3cnc4ccccc43)n2)c1 +Cc1nn(-c2ccccc2)c2sc(C(=O)N3CCCC3)cc12 +O=C(Nc1cccc(O)c1)c1ccc(N2CCCCC2=O)cc1 +Cc1cc(-c2cnc(NCc3ccco3)nc2-c2ccoc2)on1 +CCOC(=O)c1cc(-c2ccc(CC)cc2Cl)nn1CCO +O=C(NCc1ccccc1)c1ncn(-c2ccccc2)n1 +N#Cc1cccc(CSc2nnc(COc3ccc(F)cc3)o2)c1 +Cc1cc(C(=O)Nc2nc3c(Br)cccc3s2)no1 +N#CCCSc1nnc(-c2cccs2)n1Cc1ccccc1 +Cc1ccc(NC(=O)c2ccc(Cn3nc(C)cc3C)cc2)nc1 +COc1ccc(-c2nnc(SC3CC(C)OC3=O)n2C)cc1 +O=C(Nc1cccc(CO)c1)c1cc(Cl)ccn1 +O=C(Nc1ccc2c(c1)COC2)c1cc2c([nH]c1=O)CCCC2 +Cc1ccc(Cl)cc1NC(=O)c1nc2nccc(C)n2n1 +CCCC1CN(Cc2cnn(C(C)(C)C)c2)CCO1 +COC(=O)C(C)NC(=O)Cn1nnc2ccccc2c1=O +CC(Cn1ccnc1)NC(=O)c1cc(C2CC2)nc2ccccc12 +CC(C)CN1CC(C(=O)NC(C)c2nc3ccccc3[nH]2)CC1=O +O=C(Nc1cc(F)c(F)c(F)c1)c1ccc(Br)cn1 +O=C(CCc1ccc(NCc2noc(C3CC3)n2)cc1)N1CCCC1 +Cc1occc1CN(C)C(=O)Nc1cccc2cccnc12 +Cc1cc(C(=O)Nc2cc(F)c(F)cc2F)ccc1-n1cnnn1 +CC(C)(O)C1CCCN1C(=O)NC1CCN(c2ccccc2)CC1 +CCCCNC(=O)c1csc(-c2ccncc2)n1 +CCn1c(=O)c2sccc2n(CCOc2ccccc2)c1=O +Cn1c(SCC(=O)c2ccccc2)nnc1-c1cnccn1 +COCc1cc(=O)[nH]c(Nc2c(F)cccc2F)n1 +Cc1nn(CC(O)COCc2ccc(Cl)cc2)c(=O)c(C#N)c1C +O=C(Nc1ccc(Cl)cc1C(=O)N1CCCC1)C1CC2CCC1O2 +CCC(NC(=O)NCCc1cccc(C(N)=O)c1)c1nc(C)cs1 +O=C(Nc1ccc2c(c1)OCO2)c1c[nH]c2cccc(F)c12 +CC(C)NC(=O)N1CCC(C(=O)N2CCc3ncccc3C2)CC1 +CC(C)OCCn1nnc(-c2ccc(Br)cc2)n1 +CCOC(=O)C1(NC(=O)c2csc(C)n2)CCCC1 +Cc1nn2cccnc2c1C(=O)N(C)Cc1cccc(F)c1 +Cc1ccc(C(=O)N2CCC3(CC2)OCCO3)cn1 +COc1ccc2oc(CN(C)C(C(N)=O)c3cccc(F)c3)cc2c1 +COC(=O)c1cccc(NC(=O)CCn2c(=O)oc3ccccc32)c1 +CC(C)(C)OC(=O)N1CC(CNc2cccc(F)c2)C1 +CCNC(=O)c1cccc(CNC(=O)NCCc2ccccc2F)c1 +CC(=O)Nc1ccc(C(=O)Nc2ccccc2C(=O)C(C)C)cc1 +CC(C)Oc1ccc(C(=O)NCc2ccncc2)cc1 +O=C(c1cccc(Cl)c1)N(CC1=CC2N=CC=C2C=C1)C1CC1 +COC1(C)CC(NC(=O)C2CCN(c3cnccn3)CC2)C1(C)C +CCN(CC)c1ccc(C(=O)NCCNC(C)=O)cc1 +O=C(Nc1ccc(F)cc1Br)c1ccsc1 +COc1ccc(CCNC(=O)c2ccc(N3CCOCC3)nc2)cc1 +CCOc1ccc(-c2noc(-c3ccncc3)n2)cc1OC +CCOc1cc(N)cnc1Nc1cccc2cccnc12 +COc1ccc(CNc2ccc(S(C)(=O)=O)cc2)cc1 +COc1ccc(NC(=O)NCc2ccnn2C)cc1Cl +Cc1cc(C)c(S(=O)(=O)Nc2ccc3c(c2)COC3=O)c(C)c1 +O=C(CCn1cncn1)NC1CCN(C(=O)c2ccoc2)CC1 +COC(=O)CCNC(=O)c1ccc(F)c(NC(C)=O)c1 +Cc1cnc(C(=O)Nc2ccc(C(=O)Nc3nccs3)cc2)cn1 +O=C(C1CN(C(c2ccccc2)c2ccccc2)C1)N1CCCC1 +COc1ccccc1S(=O)(=O)NCc1c[nH]nc1C +CN1CCN(S(=O)(=O)c2cc(C(F)(F)F)ccc2Cl)CC1 +CNC(=O)c1ccc(NC(=O)c2ccnc(SC)c2)cc1 +Cc1cc(NC(=O)CCCOc2ccc(F)cc2)no1 +COC(=O)C1CCCC1NC(=O)NCC(F)(F)F +COC(=O)CCCc1ccc2c(c1)N(C(C)=O)CC(C)O2 +Cc1nc(C)n(CCNC(=O)c2cc(C(C)C)nn2C)n1 +Cc1cc(C(=O)NCCc2ccc(C(F)(F)F)cc2)c(C)o1 +CCOc1ncccc1CNC(=O)c1cc(C)ccc1O +O=C(c1ccc(-n2cnc3ccccc32)cc1)N1CCOCC1 +CCN1CC(COC(=O)c2cc(C)cc(F)c2)CC1=O +O=C(Nc1ccc(Cl)c(C(=O)NC2CCCCC2)c1)c1cc[nH]n1 +COCCCNC(=O)CCc1cc2ccc(C)cc2[nH]c1=O +COCCn1c(C)cn2c3c(=O)n(CC(N)=O)c(=O)n(C)c3nc12 +Cc1ccc(O)c(C(=O)N2CCN(C(=O)c3cnccn3)CC2)c1 +Cc1cc2c(SC(C)C(=O)NC3CC3)ncnc2s1 +CC(CO)NC(=O)Nc1cc(C(=O)N(C)C)ccc1Cl +CCCOc1cc(OC)cc2c1CCNC2c1ccnnc1 +COC(C)c1cccc(NC(=O)NC(C)C(C)CO)c1 +Cc1ccc(C)c(C(=O)C(C)Oc2cccc(N)c2)c1 +COc1cccc(-c2nc3ccc(N)cn3c2CC#N)c1 +CC(C)(C)C(=O)Nc1cccc(NCC(=O)N2CCCCC2)c1 +CCCC(C)(NC(=O)c1cc2cc(F)ccc2[nH]1)C(=O)OC +Cc1csc(-n2nnc(CO)c2COc2ccccc2)n1 +O=C(Nc1ccc(Oc2cccnc2)nc1)c1cc2cc(F)ccc2[nH]1 +CNC(=O)c1cc(C)ccc1NCc1nnc(C2CC2)o1 +NC(=O)Cc1ccccc1NC(=O)N1CC=C(c2cccs2)CC1 +Cc1cn2c(N)c(-c3ccc(Br)cc3)nc2s1 +COC(=O)C(C)(C)Oc1cccc(OC)c1OC +Cc1noc(NC(=O)CCc2c(C)nn(CCC#N)c2C)n1 +Cc1ccc(NC(=O)CNC(=O)CC(C)(C)C)cc1F +CCc1ccc2oc(=O)cc(CNC(=O)C3CCCO3)c2c1 +CCn1cc(S(=O)(=O)NCc2ccccc2Br)cn1 +COCC1CCCN1C(=O)CCCn1ccc2cc(Cl)ccc21 +O=C1CN(C(=O)CS(=O)(=O)c2ccc3ccccc3c2)CCN1 +COc1ccccc1NCC(=O)NC(C)Cn1nc(C)cc1C +O=C(NCCc1ccccc1Cl)c1cnn(-c2ccccc2)c1 +COc1ccc(S(=O)(=O)Nc2ccc(NC(=O)C(C)C)cc2)cc1 +CC1CN(C(=O)COC(=O)c2ccccc2NCCO)CC(C)O1 +Cc1cccc(NC(=O)C(C)Sc2nncn2C(C)C)c1C +CC(C)COC(=O)N1CCC(C(=O)NCCc2cccnc2)CC1 +Cc1ccccc1OCC(=O)Nc1nnc(-c2ccsc2)o1 +COCCN1CCOC2CCN(C(=O)c3ccc[nH]3)CCC21 +CCOc1ccc(NC(=O)Cn2c(CO)nc3ccccc32)cc1 +N#Cc1ccc(S(=O)(=O)Nc2ccccc2Cl)cc1 +COc1cc2c(c(OC)c1OC)C(=O)NCC21CCCCC1 +Cc1ccc2[nH]nc(C(=O)N(CCC#N)CCC(F)(F)F)c2c1 +CNC(=O)C1CN(C(=O)NCCc2cccs2)c2ccccc2O1 +OC(c1ccc(Cl)cc1)C1NCCc2cccc(F)c21 +CCC1CCC(CNC(=O)CCc2nc(-c3ncccn3)no2)CC1 +O=C(Cn1nc2ccccn2c1=O)N1CCOCC1 +Cc1ccn2c(=NC(=O)C(NC(=O)CC(C)C)C(C)C)[nH]nc2c1 +CCCN(CCC)c1nc2sccn2c1CO +N#Cc1c(-c2ccc(F)cc2F)nn(-c2ccccn2)c1N +Cc1cc(C(=O)c2c[nH]c3ncc(Br)cc23)no1 +CCC1(CC)CN(CCCO)c2c(N)cccc2O1 +CCNC(=O)c1ccc(NCc2nccn2C(F)F)c(C)c1 +CC(NC(=O)Nc1cccc(C#N)c1)c1ccc2c(c1)OCO2 +CCn1c(CNC(=O)NCc2ccccc2)nnc1SC +CCCCS(=O)(=O)NC(C#N)c1ccc(C)cc1 +COC(=O)c1c(C)[nH]c(C(=O)NCC(=O)Nc2ccc(F)cc2)c1C +CCc1ccccc1CNC(=O)N1CCN(CC(=O)NC(C)C)CC1 +CN(C)S(=O)(=O)N1CC2CC(C(=O)Nc3ccccc3)C(C1)O2 +CCOC(=O)Cc1nc(N)c2c(n1)SC(C)C2 +COc1ccc(-c2nnc3ccc(SC)nn23)cc1 +COc1ccc2c(c1)CC(CNC(=O)c1ccc(F)c(F)c1)O2 +CCCCn1nc(C)nc1Cc1c(C)nc(CC)[nH]c1=O +O=C(Nc1nnc(-c2ccc3c(c2)OCO3)o1)c1ccccc1Cl +Cc1cc(NC(=O)CCOC(C)C)ccc1C(=O)N(C)C +N#CCCC(C#N)CN1CCCN(C(=O)c2ccccc2Cl)CC1 +O=C1CCCCN1c1ccc(CNS(=O)(=O)c2cccnc2)cc1 +Cc1nc2sccn2c(=O)c1S(=O)(=O)NCc1ccccc1 +NC(=O)C1Cc2ccccc2N1Cc1n[nH]c(=O)[nH]1 +CC(C)Cc1ccc(C(=O)Cn2cnc(C#N)n2)cc1 +CC(OCc1ccccc1)C(=O)N1CCC(O)CC1 +COc1ccccc1CN(C)C(=O)Nc1cc(C)on1 +O=C(Nc1cnn(C2CCOCC2)c1)c1ccc(-n2cccc2)cc1 +COc1cc(OC)c(OC)cc1CNC(C)C(N)=O +CCOc1c(Br)cc(CO)cc1OC +CC(C)(C)c1ccc(OC2CC2)cc1S(N)(=O)=O +CC(C)C(=O)NCCCNC(=O)c1cn(C)nc1C(C)(C)C +Cc1nsc(N2CCCN(Cc3cnc(C(C)C)s3)CC2)n1 +Cc1nc(-c2cccc(NC(=O)C3CC(=O)N(C)C3)c2)oc1C +CC1CCCC1NC(=O)c1cccc2c1NCCC2 +Cc1ccc(-n2nnc(C(=O)NC(C)c3ccccc3)c2C)cc1F +COCCCOc1cc2c(cc1N)OCC(=O)N2 +CCc1nc2nc(C)c(CC(=O)Nc3ccccc3C)c(C)n2n1 +Cc1nc(C(C)C)sc1C(C)N(C)C(=O)Nc1cc(C)n(C)n1 +CCCC1CN(C(=O)c2ccc(SCC)nc2)CCO1 +COc1ccc(C(N)c2nc3c(s2)CCC3)cc1O +CNC(=O)c1ccc(Cl)cc1NC(=O)c1ccc(F)c(F)c1 +CN(CCO)c1ccc(-c2nc(C3CCOC3)no2)cc1 +CC(=O)c1cccc(NC(=O)COc2cccc3c2CCCC3O)c1 +COc1ccc(OC)c(C(=O)COC(=O)c2ccc(O)cc2O)c1 +COc1ccc(OCC(=O)N(C)CCc2ccccn2)cc1 +CCc1cc(C(=O)Nc2cc(OC)ccn2)sc1C +CCc1ccc2occ(CC(=O)NC(C)COC)c2c1 +CC(=O)c1nc2cc(F)ccc2n1Cc1cccnc1N +Cc1nscc1C(=O)OCc1ccccc1NC(=O)c1ccco1 +COc1ccc2cc(C(=O)N3CCn4cccc4C3C)[nH]c2c1 +O=c1c2c3c(sc2ncn1CCCCc1ccccn1)CNCC3 +Nc1ccccc1OCCCn1cnc2ccccc21 +O=C(c1ccc(N2CCOCC2)cc1)c1cccs1 +Cc1csc(C2CN(Cc3c[nH]nc3C)CCO2)n1 +CC(NC(=O)Nc1cccc(S(=O)(=O)C2CCCC2)c1)C1CC1 +CC(C)CCN1C(=O)C(C)(C)Oc2ccc(CO)cc21 +O=C(Nc1ccc(F)c(F)c1F)NC1c2ccccc2CC1O +O=C(NCc1ccncc1)c1ccc(OC2CCCC2)cc1 +COc1c[nH]c(C(=O)NCCN2CCc3ccccc32)cc1=O +COc1ccc(C(=O)Nc2cccc(NC(C)=O)c2)cc1 +CCOC(=O)C(Cc1ccc(O)cc1)Nc1nc2ccccc2o1 +O=C(NCc1ccncc1)c1cc(-c2ccc3c(c2)CCO3)n[nH]1 +O=S(=O)(Nc1ccc2c(c1)OCO2)c1ccccc1F +N#CCCN(CCC#N)CC(=O)Nc1ccc(Cl)cc1 +CCc1c(C)nc2n(c1=O)CN(CCO)CN2c1ccc(C)cc1 +CCN(CC)C(=O)C(C)Sc1nnc(N2CCCC2)n1C1CC1 +CC1(C(=O)Nc2cccc3ncccc23)CC1(Cl)Cl +CC(C)COCC(O)CNc1cc(F)cc(F)c1F +Nc1cccc2c1CN(c1cccc3ccccc13)C2=O +CC(C)Cc1cc(-c2nc(CCc3ccccc3)n[nH]2)nc(N)n1 +O=C(NCCc1cccc(O)c1)c1ccc2c(c1)OCO2 +CN1C(=O)c2ccccc2NC1C1=Cc2cc(Cl)ccc2OC1 +N#Cc1ccc(NCCc2ccc(F)c(Br)c2)nc1 +Cc1ccc(F)c(S(=O)(=O)NC2CN(c3ccccc3)C2=O)c1 +Cc1cc(=O)oc2cc(OC(C)C(=O)N(C(C)C)C(C)C)ccc12 +CCCNC(=O)Nc1ccc(F)c(N2CCCS2(=O)=O)c1 +CCOc1ccc(CNc2ccc(N3CCCC3=O)cc2)cc1OC +NS(=O)(=O)N(Cc1ccco1)Cc1ccco1 +Nc1nc2c(c(=O)[nH]1)CCN(C(=O)c1cnccn1)C2 +C=C(C)CN(CC)C(=O)NC(c1ncc(C)s1)C1CC1 +CCN1CC2(CCN(C(=O)CC(F)(F)F)CC2)c2ccccc21 +N#CCCN(CCC(F)(F)F)C(=O)c1cccs1 +COCCNC(=O)c1nccc2c(N)c(C)ccc12 +CC1CN(CC(O)c2ccc(S(C)(=O)=O)cc2)C(C)CO1 +CC(C)CCN(C(=O)CC1OC(=O)c2ccccc21)C1CC1 +Nc1ccnc(CNc2nccc(OCc3ccccc3)n2)n1 +COC(=O)C1Cc2ccc(Br)cc2CN1 +CCC1CCN(S(=O)(=O)c2ccc(=O)[nH]c2)CC1 +CC(C)(C)N1CC(C(O)c2cccs2)CC1=O +COCc1oc(-c2ccc(OC)c(Cl)c2)cc1CO +C=CCn1c(=O)c2cnc(-c3ccncc3)nc2n(C)c1=O +CC(C)c1cncnc1N1CCC(N2CCOCC2)C(CCCO)C1 +CC(C)C(CNC(=O)c1scnc1C1CC1)c1cccnc1 +CC(C)(C)OC(=O)N1CCCn2nc(CO)cc2C1 +CCCn1nc(C)cc(-c2nnc(NCC(C)C)s2)c1=O +COc1ccccc1C(=O)NCc1cc(C(C)C)no1 +Cc1cc(C(=O)N2CCC(C(N)=O)c3ccccc32)nn1C(C)(C)C +CC(=O)Nc1cc(C)ccc1OCc1cc(=O)n2oc(C)cc2n1 +COc1ccc(CN2CCN(C(=O)c3cnccn3)CC2)cc1OC +COc1ccccc1NC(=O)CCc1cccs1 +O=S(=O)(Nc1cn[nH]c1)c1cc(Br)ccc1Cl +Cc1csc(NC(=O)c2nn(C)c3ccccc3c2=O)n1 +NC(=O)C1CC(=O)N(c2ccc(-c3nc4ccccc4s3)cc2)C1 +Cc1ccc(CCNC(=O)c2csnc2C)o1 +Cc1nn(C)c2ncc(NC(=O)c3cc4ccccc4oc3=O)cc12 +COc1cccc(-n2ccnc2SCC(C#N)CCC#N)c1 +COc1ccccc1NC(=O)c1sc2nc3c(cc2c1N)CCC3 +Nc1cc(Cl)ccc1NC(=O)CN1CCOC1=O +CCN1CCOC(CCNC(=O)c2onc3ccccc23)C1 +CCC(=O)Nc1cccc(NC(=O)N2CCc3cc(F)ccc3C2)c1 +COCC(=O)N1CCC(Cc2nnc(-c3ccccc3)o2)CC1 +CCC(NCc1cccc(C(N)=O)c1)c1nccs1 +CCn1nc(C(=O)Nc2cc(C)cc3cccnc23)ccc1=O +CCn1cc(CC(=O)Cc2c(F)cccc2Cl)cn1 +CC1Cc2cc(C(=O)C(C)N3CC(C)OC(C)C3)ccc2N1 +Cc1cc(C2NC(N)=Nc3nc4ccccc4n32)c(C)n1C(C)C +CCC1CCCN(C(=O)c2c[nH]nc2-c2ccc(F)cc2)C1 +CC(C)CC(NC(=O)CSc1nc(N)cc(N)n1)c1ccccc1 +CCCNc1cccc(C(=O)NC(C)COC)n1 +COc1cc(Cl)cc(C(=O)N2CCc3c(nc[nH]c3=O)C2)c1 +CC(NC(=O)c1cccc2ccccc12)C1CCCO1 +CC1CN(CCCNC(=O)NCc2cccnc2)CC(C)O1 +CCC1CN(C(=O)c2cc(C3CC3)nc3c2cnn3C(C)C)CCO1 +CC(C)c1csc(NC(=O)CCC2CCCO2)n1 +CCc1n[nH]c(C2CCN(C(=O)c3ccc(OC)nc3OC)CC2)n1 +CC(C)OCCOC(=O)c1cnn(C(C)(C)C)c1 +O=C(Nc1nc2c(s1)CCC2)c1cccc(N2CCOC2=O)c1 +COc1ccc(Cl)cc1CNC(=O)N(C)Cc1ccccn1 +CC(C)C(C)NC(=O)NCC1(c2ccc(F)cc2)CCOCC1 +Cc1noc(C)c1CN1CCN(C(=O)c2ccncc2)CC1 +O=C(CCc1ccco1)Nc1cccc(S(=O)(=O)C(F)F)c1 +COc1ccc(S(=O)(=O)Cc2noc(C)n2)cc1 +O=C(c1ccco1)N1CCCC1c1ccccc1F +c1csc(CN(c2ccc3nnnn3n2)C2CC2)c1 +COc1ccc(CNC(=O)Cn2ccccc2=O)cc1OC +COC(=O)c1cc(NCc2ccncn2)ccc1Cl +CC(C)CC(=O)Nc1ccc2c(c1)CC(C(=O)NC(C)C)CO2 +Cc1cc(O)ccc1NC(=O)c1nnc(CN)c2ccccc12 +O=C(CC(C1CC1)C1CC1)N1CCCCC1c1nccs1 +COC(=O)c1ccsc1NC(=O)c1ccccc1 +CC(C)CNC(=O)c1nn(-c2ccccc2)c(=O)c2ccccc12 +O=C(Cn1nnn(-c2cccs2)c1=O)NCC1CCOC1 +O=C(Cc1csc(NC(=O)NC2CCCC2)n1)NC1CCCC1 +CCOCCc1nnc(NS(=O)(=O)c2ccc(F)cc2)s1 +Cc1ccccc1NS(=O)(=O)c1c(C)n[nH]c1C +COc1ccc(S(=O)(=O)NCc2ncn(C)n2)cc1Cl +CCCCC(=O)N1CCc2ccc(OCC)cc2C1 +COc1cc(N2CCC(=O)C2=O)cc(OC)c1OC +CC(C)CCCC1CN(C(=O)CCN2CCCCCC2=O)CCO1 +COc1cc(OC)c2cc(Br)c(=O)oc2c1 +CSc1ccsc1C(=O)Nc1ccc(S(C)(=O)=O)cc1C +CCC(C)NC(=O)NCc1ccc(S(C)(=O)=O)cc1 +Cc1nc(C2CCCN(C(=O)CCn3cncn3)C2)sc1C +CCCN(CC(=O)N(C)C)c1cc(COC)nc2ncnn12 +COc1ccnc(NC(=O)C2CC(=O)N(CC(F)(F)F)C2)c1 +O=C(NCCCC1CCCC1)c1ccc(S(=O)(=O)C(F)F)cc1 +COC(=O)CSc1ccc2c(N)c(C(=O)OC)sc2c1 +Cn1nc(CC(=O)Nc2ccc(Cl)cn2)c2ccccc2c1=O +Clc1cccc(NC2CCOCC2)c1-n1cncn1 +CN1C(=O)CCC12CCC(NC(=O)c1cccnc1)CC2 +N#CC(CCC(=O)Nc1ccccc1Cl)c1ccccn1 +CC(=O)NCCNC(=O)Nc1cccc(C#Cc2ccccc2)c1 +CC(C)C(=O)N1CCN(c2cc(N(C)C)cnn2)CC1 +CCOC(=O)c1sc(=O)[nH]c1-c1cc(OC)ccc1OC +O=C(Nc1ccc(-c2csnn2)cc1)c1cc[nH]n1 +CC1CCN(C(=O)C(O)c2ccc(Cl)cc2)CC1 +O=C(Nc1ccc(Cl)c(Cl)c1)N(Cc1ccncc1)C1CC1 +CC1Sc2ccc(C(=O)NC3C4CCOC4C3(C)C)cc2NC1=O +CC(Oc1ccccc1C#N)C(=O)Nc1ccnn1C(C)C +CCc1nc(C2CCCN2C(=O)CCn2ccccc2=O)no1 +CCOc1ccccc1OC1CCN(C(=O)C2CCCO2)CC1 +O=c1ccc(C(F)(F)F)cn1-c1ccc(C(F)(F)F)cn1 +O=C(C1CC=CCC1)N1CCC(OCc2cccnc2)CC1 +CN1C(=O)CSc2ccc(C(=O)NC3CC3)cc21 +N#Cc1cccc(NC(=O)c2ccc(N3CCCCCC3)nc2)c1 +CC(CCc1ccccc1)(NCC(F)(F)F)C(N)=O +CCc1nc(CC(=O)Nc2ncn(Cc3cccnc3)n2)cs1 +CC(NC(=O)CNc1cccc(C(F)(F)F)c1)c1ccncc1 +C=CCOC(C)C(=O)NCc1ccc(NC(C)=O)cc1 +CN(C)S(=O)(=O)N1CCC(c2nc3ccccc3s2)CC1 +Cn1cc(C(=O)N2CCC(CN3CCOCC3)CC2)c2ccccc21 +Cc1ccccc1Cc1nc(Cn2cncn2)nn1C1CCCCC1 +NC(=O)c1ccc(NC(=O)c2cncc(Br)c2)cc1 +O=c1[nH]c(Cn2nnc(-c3ccccc3)n2)nc2cc(Cl)ccc12 +CC(C)NC(=O)COc1ccc2c(c1)C(=O)CC(C)(C)O2 +CCCC(C)NC(=O)C(C)Oc1cccc(C)c1N +CCOc1cccc(NC(=O)Cc2ccccc2O)n1 +O=C(CNc1ccccc1)Nc1cccc(C(=O)N2CCOCC2)c1 +CC1(C)CN(C(=O)NCCNC(=O)C2CC2)CCO1 +Cn1cccc1-c1csc(NC(=O)C2(c3ccccc3)CCC2)n1 +CCc1ccc(S(=O)(=O)Nc2ccc(NC(C)=O)c(O)c2)cc1 +CNS(=O)(=O)c1ccc(C(=O)N2CCOC3CCCCC32)cc1 +COc1ccc(-c2nnc(SCc3csc(C)n3)n2N)cc1 +CC(C1CC1)N(C)C(=O)CCc1nc2ccccc2c(=O)[nH]1 +O=S(=O)(NC1C2CCCCC21)c1cccc2nonc12 +O=C(c1c[nH]nn1)N1CCc2[nH]nc(C3CCC3)c2C1 +CCCCOC(=O)c1ccc2c(=O)n(C)c(=O)n(C)c2n1 +CS(=O)(=O)NCCC(=O)NCCc1ccccc1Cl +Nc1cccc(Cl)c1SCC(=O)N1CCCC1 +Cc1ccc(C(=O)NC(C)c2cccc(S(N)(=O)=O)c2)cc1C +Cc1ccc(S(=O)(=O)C2(C(=O)NC3CCCCC3)CC2)cc1 +Cc1cc(C(=O)Nc2cc(C(F)(F)F)ccc2-n2cncn2)on1 +CCc1c(C)nc(Cc2cccc(Cl)c2)[nH]c1=O +CCc1cccc(CC)c1NC(=O)COc1cccc(N)c1 +COC(=O)CNC(C#N)c1cccc(OC)c1OC +COc1cccc(CC(=O)Nc2ccc3c(c2)CC(=O)N3C)c1 +CC(C)c1cc(C(=O)N2CCC(Cn3cc(CO)nn3)CC2)no1 +CCC(=O)Nc1ccccc1C(=O)N(C)Cc1ccccc1 +Cc1cc(NC(=O)Nc2ccc(-n3ccnc3)c(Cl)c2)no1 +O=C(c1ccsc1)N1CCC(CCOCc2cccc(F)c2)CC1 +COC(=O)CN(C)S(=O)(=O)c1ccc(C)s1 +Cc1cc(NC(=O)CCNc2ccccc2)n(C)n1 +CCOC(=O)c1cc2cc(Br)ccc2o1 +CCC(C)NC(=O)Nc1cccc(Cn2ccnc2C(C)C)c1 +COc1ccc(CC(=O)Nc2nnc(-c3ccco3)o2)c(OC)c1 +CCCNC(=O)NC1CCN(c2nccs2)CC1 +CC(=O)c1ccc(Oc2ccc3c(c2)OCO3)c(N)c1 +CSc1c(F)cc(NC(=O)N2CCC(CO)CC2)cc1F +CC(C)CC(=O)Nc1ccc(S(=O)(=O)Nc2ncccn2)cc1 +CCOC(=O)c1[nH]cnc1C(=O)Nc1ccccc1 +NC(=O)CCCNC(=O)Cn1c(=O)oc2ccccc21 +COc1ccc(NCCOCC(F)(F)F)cn1 +O=C(Nc1cccc(O)c1)C1CCCN1C(=O)OCc1ccccc1 +Cc1cc(NS(=O)(=O)c2ccccc2-c2ccccc2)n(C)n1 +CC(C)(C)CC(=O)NCc1ccc(OCc2cccnc2)cc1 +CCCCNC(=O)N1CCN(C(=O)c2ccc(CC)cc2)CC1 +COc1ccccc1NC(=O)NCC(O)CN1CCOCC1 +CN(Cc1nnc2n1CCC2)C(=O)NCCCN1CCCCCC1=O +Cc1cccc(NC(=O)CC2NC(=O)c3ccccc3NC2=O)c1 +CC1CCCC(CNC(=O)CCC(=O)c2ccccc2)C1 +CC(Nc1ccc(NC(=O)C2CC2)cc1)c1nc2ccccc2c(=O)[nH]1 +O=C(NCc1ccncc1)c1ccc(CN2CCCC2=O)cc1 +COc1ccc(NC(=O)C2CCN(S(N)(=O)=O)CC2)cn1 +Cc1cccc(CNC(=O)Nc2ccc(OC(C)C)cc2F)n1 +O=C(COc1cccc2cccnc12)NCc1ccccc1 +Cc1cc(C(=O)N2CCN(CCN(C)c3ccccc3)CC2)c(C)o1 +CCNC(=O)N1CCC(n2cnc3cccnc32)CC1 +CN(Cc1cc(Br)cn1C)C(=O)c1cscn1 +COC(=O)c1ccc(Nc2ncnc(OC(C)C)c2N)cc1 +CNc1cc(C2CN(Cc3coc(C)n3)CCO2)nc(C)n1 +CC(=O)OCC(=O)Nc1cccc2c1Cc1ccccc1-2 +COC(=O)c1cccc(NC(=O)Cc2c[nH]c3ccccc23)c1 +CC1CCCC(NC(=O)c2cccnc2N2CCOCC2)C1C +Nc1ccsc1-c1nc(-c2cccc(F)c2)no1 +NS(=O)(=O)N1CCC(C(=O)N2CCCC(C(F)(F)F)C2)CC1 +COc1cccc(C(=O)CCOc2ccccc2)c1 +COc1ccccc1C(O)CNC(=O)COC1CCCC1 +CCOC(=O)c1c(C)[nH]c(NC(=O)Nc2cccc(OC)c2)c1C +CC(=O)c1ccc(NC(=O)NC2(c3ccccc3F)CC2)cc1 +Cc1cc(S(=O)(=O)n2nc(-c3cccc(F)c3)cc2N)ccc1F +CN(Cc1ccc(O)cc1)C(=O)C1CCN(S(C)(=O)=O)CC1 +CC(=O)N1CCN(CC(=O)N2CCC(C(N)=O)CC2)CC1 +O=C1CCCN1Cc1nc(C2(c3ccccc3)CC2)no1 +Cc1c(C(=O)N(C)CCC(F)(F)F)cnn1-c1ccccn1 +O=C(Nc1nc2c(s1)CCCC2)N1CCOCC1C1CC1 +Cc1cc(F)cc2c1N(C(=O)c1cn(CC(=O)N(C)C)nn1)CCC2 +Cc1ccc(C(=O)OCC(=O)NCCC2=CCCCC2)cn1 +CCOC(=O)CSc1nnc(-c2cccnc2)n1-c1ccccc1 +COc1ccc(F)cc1NC(=O)c1ccc(C)cn1 +CCNC(=O)N1CCN(C(=O)c2cc(C)n(C3CC3)c2C)CC1 +O=C(NCCc1cccs1)c1ccc2cncn2c1 +Cc1ccc(-c2noc(C(=O)Nc3cc(C)ccn3)c2N)cc1 +OCC1(c2nc(C3CCOCC3)nn2CC(F)(F)F)CC1 +CCOC(=O)N1CCc2nc(NC(=O)c3cccs3)sc2C1 +COC(=O)c1ccc(C(=O)Nc2ccc(F)c(Cl)c2)cn1 +N#Cc1cccc(NC(=O)CCCN2CCOCC2)c1 +CC(C)CCOC1CCCCC1NC(=O)C1CCCN(C(N)=O)C1 +CCOC(=O)CC(C)CNC(=O)c1nc2nccc(C)n2n1 +COC(=O)c1ncccc1OCc1ccn(C(C)C)n1 +CC(C)(C)C(=O)COC(=O)c1ccc2c(c1)OCO2 +Cc1ccc(CC(=O)Nc2ccnn2CCc2ccccc2)cn1 +CCn1c(C)ccc(C(N)c2cc(C)ccc2C)c1=O +CN(C)c1ccc(-c2nnc(-c3nonc3N)o2)cc1 +CCc1nc(COC)sc1-c1csc(NC)n1 +COCCN1CC(C(=O)N(C)CC2CC2)CC1=O +CN1C(=O)C2(CCN(C(=O)c3cccs3)CC2)c2ccccc21 +NC(=O)C1CCN(C(=O)c2cn(CC(O)c3ccccc3)nn2)CC1 +CC(NCc1nnc2n1CCCC2)C(=O)NCC(C)c1ccccc1 +CCCCC(=O)c1ccc(S(=O)(=O)C(C)C)cc1 +CCc1nnnn1Cc1cc(=O)n2ccsc2n1 +CCOCc1ccccc1CNC(=O)c1ccnc(-n2ccnc2)c1 +Cc1cc(=O)oc2cc(OCC(=O)Nc3ccc(F)cc3)ccc12 +CCCNC(=O)Cc1n[nH]c2c(Cl)cccc12 +Cc1nc2ccc(F)cc2cc1C(=O)NC1CCCCC1 +COCC(C)N(C)C(=O)c1nc(S(C)(=O)=O)n2ccccc12 +CC(C)CNC(=O)c1ccccc1NCC(=O)Nc1ccccc1 +CC(C)NC(=O)c1ccc(NC(=O)C(NC(N)=O)C(C)C)cc1 +COc1ccc(NC(C)=O)cc1NC(=O)Cc1ccc[nH]1 +Cc1ccc2cc(-c3nc(C4CC4)no3)c(C)nc2c1 +O=S(=O)(c1ccc2c(c1)CCCC2)N(CCO)CCO +Cc1cc(C(=O)NC(C)c2ccccc2Cl)c2c(=O)[nH]n(C)c2n1 +CCc1cccc(OCC(O)Cn2cnc3ccccc32)c1 +CC(C)c1noc(CCNC(=O)CN(C)C(=O)c2cccs2)n1 +CCc1noc(C(C)N2CCN(C(=O)c3ccc(F)cc3)CC2)n1 +O=C1Nc2ccccc2C12CCCN(c1ncnc3[nH]ccc13)C2 +Cc1cc(NC(=O)c2cccc(NC(=O)C3CC3)c2)c2ncccc2c1 +COCC(C)(C)C(=O)N(CCO)Cc1ccccc1C +CCOC(=O)C1=C(CNc2ccc(Cl)c(F)c2)NC(=O)NC1C +CC(=O)NC(C)(C)c1noc(-c2ccc(-c3ccccc3F)s2)n1 +CCC(C)(C)OCc1ccc(C#CCO)cc1F +CCc1cc(NC(=O)c2ccccc2SCc2cscn2)[nH]n1 +CC(C)Cc1cc(C(=O)NCc2cc(N3CCOCC3)ncn2)on1 +CC(=O)NCCNC(=O)N1CCCC(c2nc3ccccc3o2)C1 +COc1ccc(OCc2noc(CNC(=O)c3cn(C)nn3)n2)cc1 +CCCNC(=O)C1CCN(c2ncccc2-n2cccc2)CC1 +O=C(NCc1cc(C2CC2)n(C2CCCC2)n1)Nc1cccs1 +COCc1ccccc1CNC(=O)CC1CC2CCC1C2 +O=C(CC1C=CCC1)NC1c2ccccc2CC1O +CSc1nnc(SC(C)C(=O)c2ccccc2)s1 +COCc1ccccc1CNC(=O)CSc1ncc2ccccn12 +CNC(=O)c1ccc(NC(=O)N2CCCN(C(=O)OC)CC2)c(C)c1 +Cc1ocnc1CNS(=O)(=O)N1CCCCC1 +Cc1nc(CC(=O)Nc2ccc(C(C)(C)C)nn2)cs1 +CCCc1c(CO)nnn1-c1cccc(C(=O)OC(C)C)c1 +CCCCN(CC)C(=O)CN1CCN(c2ccccc2F)CC1 +Oc1cc2c(cc1Cl)CCNC2c1ccnnc1 +OCc1ccccc1OCCCOc1ccccc1 +COc1cccc(C(=O)NCCc2ccccn2)c1F +CCc1nc2n(n1)CCCC2NC(=O)c1ccnn1C +Cc1ccc(C(O)CNS(=O)(=O)Cc2ccccc2)o1 +CCOCCCNC(=O)Nc1ccc2nc(C(C)C)sc2c1 +CN(CCC#N)S(=O)(=O)NC(C)(C)CC(C)(C)C +O=C(c1cc(F)cc(F)c1)N1CCC(C(O)c2ccccc2)CC1 +Cn1nccc1C(=O)OCC1CCOc2ccccc21 +CC(C)(C)OC(=O)N1CCc2nc(C(C)(C)C)ncc2C1 +O=C(OCCOCC(F)(F)F)c1cccc2c1OCO2 +Cc1cc(C(=O)NCCc2ccccc2)c(C)n1C1CC1 +CCC(CC)NS(=O)(=O)c1cc(F)cc(F)c1 +COc1cc(OC)cc(C(=O)NCC(=O)NCc2ccccc2F)c1 +Cc1csc(C(C)NC(=O)Cc2c[nH]c3c(C)cccc23)n1 +O=C(c1cc(-c2ccc(O)cc2)on1)N1CCCC1 +COc1ccc(C(=O)NCCCn2ccc3cccnc32)c(OC)c1 +CCCC(=O)N1CCCC(C(=O)NCc2nc3ccccc3[nH]2)C1 +COC(=O)CCNC(=O)CCc1c[nH]c2ccccc12 +COCc1nnc(NC(=O)C2CC(=O)N(c3ccccc3)C2)s1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(Cl)cc1 +Cc1ccc(C(=O)N2CCOCC2C2CC2)s1 +CCC(C)C(=O)NC(C)c1cc(OC)c(OC)c(OC)c1 +CC(NC(=O)c1ccncc1)c1cc(=O)[nH]c(-c2cccnc2)n1 +Cc1ccccc1OC(C)C(=O)NC(CO)C(O)c1ccc(N)cc1 +CCN(CC)C(=O)N1CCC(C(=O)Nc2ccnn2C(C)C)CC1 +CC(C)CN1CCOC(COC(=O)CC2CCCC2)C1 +Cc1nonc1N(Cc1ccc(F)cc1)S(=O)(=O)c1ccccc1 +CC(C#N)CN(C)C(=O)C1CCCC(C(=O)N(C)CC(C)C#N)C1 +CC(C)(C)NC(=O)c1ccccc1NC(=O)NCc1cccnc1 +COC(=O)C1(c2ccccc2)CCN(c2ccc3nccnc3n2)CC1 +Cc1noc2nc(-c3cccs3)cc(C(=O)N3CCOCC3)c12 +CN1CCN(C(=O)c2ccn3c(-c4ccccc4)nnc3c2)CC1 +CC(C)(C)c1ccc(NC(=O)NCc2nnc3n2CCCCC3)cc1 +COC(=O)C(C)CNc1cc(OC)cc(OC)c1 +CN(Cc1ccco1)C(=O)CSc1ccccc1O +CC(C)OC(=O)CCN1C(=O)c2ccccc2S1(=O)=O +Cc1cc(C(=O)NCc2ccccn2)c(NC(=O)C(C)(C)C)s1 +O=C(Cc1ccc2c(c1)OCO2)NCc1cscn1 +CCn1cc(Br)c(C(=O)Nc2nccs2)n1 +CCOC(=O)c1cc2sccc2n1CC(=O)N1CCCC(C)C1 +CNc1ncnc(Nc2nc3ccccc3s2)c1N +COCc1cccc(NC(=O)c2cc(Cl)ccn2)c1 +Nc1ccc2c(c1)nc(C(F)(F)F)n2Cc1cccnc1 +CN(C(=O)C1CC1)C1CCCN(c2ccccc2)C1 +CCC1C(=O)NCCN1Cc1csc(-c2ccccc2OC)n1 +CC(C)(C)OC(=O)Nc1cc(N)ccc1CCO +Cc1n[nH]c(C2CCCCN2C(=O)OC(C)(C)C)n1 +Cc1cccc(NC(=O)NCc2ccc(S(C)=O)cc2)c1Cl +CC1=Nc2ncnn2C(c2ccccn2)C1C(N)=O +Cc1ccccc1NC(=O)c1nnn(-c2ccc(F)cc2)c1C +Cc1ccc(-n2c(=O)[nH]c3sc4c(c3c2=O)CCCC4)cc1 +CCc1c(C)c2ccc(NC(=O)c3cc(C)on3)cc2[nH]c1=O +CCCCOc1cccc(CNc2nncs2)c1 +O=C(c1cccc(Br)c1Cl)N1CCC2(CCOC2)C1 +O=C(CCc1ncc(-c2ccc(F)cc2F)o1)NCc1ccncc1 +CCc1onc(C)c1NC(=O)c1cccc2cn[nH]c12 +COc1cc(C(=O)NCc2ccc(F)cc2F)on1 +Cc1ccn2c(=NC(=O)C(C)Oc3ccc(F)c(F)c3)[nH]nc2c1 +Cc1cnc(NC(=O)CNC(=O)c2ccoc2)s1 +CCOC(=O)C(C)N(C)S(=O)(=O)c1cccc(C(=O)N(C)C)c1 +O=C(NC1CCCC1)C1CCCN1C(=O)c1ccccc1 +Cc1ccc(C(=O)N(C)CC2Cc3ccccc3CN2C)c(F)c1 +CN(Cc1ccncc1)C(=O)NCCNC(=O)c1cccnc1 +CC=CCOC(=O)CCC(=O)c1ccc(C)s1 +O=C(C(Nc1ccc2c(c1)CCC2)c1ccccc1)N1CCOCC1 +COc1ccc2c(C)cc(SC3CCOC3=O)nc2c1 +O=C(COCC12COCC1CN(c1ncccn1)C2)N1CCCC1 +Cc1cc(C)n(CC2CCCN2C(=O)c2ccc3cc[nH]c3c2)n1 +Cc1noc(CSc2nnnn2Cc2cccs2)n1 +CCn1cc(C2=Nn3c(nnc3C(F)F)SC2)c(C)n1 +CC(OCC1CCCCO1)C(=O)Nc1ccc(-n2cncn2)nc1 +CCn1c(SCCOc2ccc(C#N)cc2)nnc1-c1ccco1 +OCC1(CC2CCCCO2)CCN(c2cnc3ccccc3n2)CC1 +CC(C)CC(=O)NCc1ccc2c(c1)CCN2C(=O)C(C)C +COc1ccc(CCn2nc(-c3cccc4ncccc34)oc2=O)cc1 +O=C(c1cccc(Cl)c1Cl)N1CCC(CO)CC1 +CC1(CCNC(=O)NCCc2c[nH]c3ccc(F)cc23)OCCO1 +Cc1c(C(=O)NC(C(N)=O)c2ccccc2)cnn1C(C)(C)C +Cc1nc2nc(C)c3c(=O)n(-c4nc5ccccc5[nH]4)ccc3n2n1 +CCNC(=O)N1CCCC1c1nnc2n1CCCCC2 +O=C(c1occc1CS(=O)(=O)c1ccccc1)N1CCOCC1 +Cc1ccccc1OCC(=O)NCCNC(=O)c1cccnc1 +CNC(=O)CN1CCOC2CN(C(=O)c3ccoc3)CC21 +O=C(CCNC(=O)NC1CCCCC1)NCCc1ccccc1 +CC(C)(C)CC1CCCN1C(=O)Nc1nnc(C(F)(F)F)s1 +COc1ccc(OCc2ncc(-c3ccccc3)o2)c(C(N)=O)c1 +CC(=O)Nc1cccc(-n2cnnc2SCc2ccc(F)cc2)c1 +CCCOc1ccccc1-n1nnc(CO)c1-c1ccncc1 +COc1ccc(F)c(NC(=O)C2CCN(c3cnccn3)CC2)c1 +Cc1cc(C)c(CNC(=O)Cn2cncn2)c(C)c1 +COc1ccccc1CC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +CC(C)CCn1nc(-c2ccc(F)c(F)c2)cc(C#N)c1=O +CCc1noc(CC)c1CC(=O)NCCc1nc2ccccc2s1 +C#CCN1CCN(C(=O)CNc2ccccc2COCC)CC1 +CC(C)CC(=O)NCc1cccc(NC(=O)c2ccc(F)cc2)c1 +C#Cc1cccc(NC(=O)NCc2ncoc2C)c1 +COc1ccccc1C(=O)NCC(C)(C)N1CCOCC1 +COc1ccc(CNC(=O)N2CC(C)c3ccccc32)c(OC)c1 +O=C(Nc1ccccc1N1CCCCC1)c1ccc2[nH]cnc2c1 +O=C(N1CCOCC1)N1CCN=C1Cc1cccc2ccccc12 +COC(=O)c1sccc1S(=O)(=O)N1CCCc2ccccc21 +CCc1cnc(NC(=O)CCc2cccnc2)s1 +O=C(NCc1nncn1C1CC1)Nc1cccc(NC(=O)C2CC2)c1 +Cc1nn(C)c2nc(N3CCN(Cc4ccc(F)cc4)CC3)sc12 +CC1CCN(C)c2ccccc2N1C(=O)c1ccc(=O)n(C)c1 +CCOc1cc(N2CCN(C(C)=O)CC2)nc(C)n1 +CC(=O)N1CCc2nc(NC(=O)NC3CCCC3)sc2C1 +CC(C)(C)OC(=O)NC(C)(C(=O)Nc1ccc2c(c1)COC2)C1CC1 +CCN(Cc1ccccc1)C(=O)c1ccc(OC)c(F)c1 +CC1CC1C(=O)N1CCCCC1C(=O)NCc1ccc(F)cc1 +CC(C)OCCC(=O)NC(c1nc2ccccc2[nH]1)C(C)C +O=C(NCCCN1CCOCC1)c1cc2c(s1)CCCCC2 +CCCc1nc(C)c(CNC(=O)C2CC(=O)N(C3CC3)C2)s1 +CC(C)c1ccccc1OCc1ncc(C#N)s1 +Cc1cccc(C)c1NC(=O)C(C)OC(=O)c1ccncc1F +COC(=O)c1sc2cnccc2c1-n1cccc1 +COc1ccccc1Nc1ncccc1C(=O)NCCC(N)=O +Cc1ccc(NC(=O)N(C)C(C)CC#N)cc1OCC(F)F +Cc1cc(C)cc(OCC(=O)Nc2ncccc2C)c1 +CC(=O)NCC1NCCc2c(OC(F)F)cccc21 +Cc1ccc(C(O)CCC(=O)NCc2ccncc2)cc1N +Cc1ccc(C)c(C(=O)N(CCC#N)Cc2cccnc2)c1 +CCC(=O)N1CCN(Cc2nnnn2-c2ccccc2)CC1 +NC(=O)c1cccc(OC(=O)c2cccc3ccccc23)c1 +Cc1c(Cl)cccc1NC(=O)CSc1nnc(C(C)C)n1C +O=C(Cc1ccc2ccccc2c1)NCCNC(=O)c1ccc(O)cc1 +O=C(NCc1cc(F)ccc1Br)C1CC2CCC1O2 +Cc1nc(NC(=O)N(CC(C)C)CC(F)(F)F)sc1C +Cc1cnc(NC(=O)c2sc3ccc(F)cc3c2C)s1 +Cc1ccccc1C(=O)NCC(=O)N1CC(C)CC(C)C1 +CCCCc1nnc2sc(-c3cc(N)ccc3Cl)nn12 +CC(C)(C)c1cnc(CNc2ccc(C(=O)N3CCOCC3)cc2)o1 +CN(C(=O)c1cn(C)nc1-c1ccc(F)cc1F)C1CCCCC1 +COc1ccc(NC(=O)CN(C)S(C)(=O)=O)c(Cl)c1 +O=C1CC(c2cccs2)Cc2[nH]c(=O)c(C(=O)NC3CC3)cc21 +Cc1noc(C2CC3CCN(c4ncc(F)cn4)CC3O2)n1 +CC(=O)Nc1ccc2nc(NC(=O)C3CCCC3)sc2c1 +CC(NC(=O)c1cc2ccccc2[nH]1)c1ccc(-n2cncn2)cc1 +CCCS(=O)(=O)Nc1cc(N2CCCS2(=O)=O)ccc1OC +COCn1c(-c2ccccc2OC)ccc(C#N)c1=O +CCCC(=O)NCC(=O)NC(C)c1cccc(N2CCCC2)c1 +Cn1nc(C(F)(F)F)cc1C(=O)c1ccccc1 +O=C(NCC1CC1)C1CCN(C(=O)c2cccnc2)CC1 +CN(C)c1nc(Cn2[nH]c(C(C)(C)C)c(CCC#N)c2=O)ns1 +Cc1occc1-c1nnc(SCCCCCO)n1C +CCOC1CCCN(C(=O)c2nn(-c3ccccc3)nc2C)C1 +COc1ccc2c(c1)C(CSc1nnnn1C)NCC2 +O=C(Nc1ccc(Cl)cc1)N1CCN(C(=O)c2ccsc2)CC1 +CCCn1nc(C)c(NC(=O)NCc2ccc(O)cc2)c1C +CCc1ccc(C(=O)Nc2ccc(C#N)cn2)cc1 +CCOCCn1c(=NC(C)=O)sc2cccc(OC)c21 +COC(=O)C1(c2ccccc2)CCN(C(C)=O)CC1 +CCC1Oc2ccc(N)cc2N=C1N=c1cc(C)cc[nH]1 +Oc1ccccc1-c1nc(C=Cc2ccncc2)no1 +COc1ccc(OCc2cc(C(=O)NC(C)C)n[nH]2)c(Cl)c1 +COc1cc(OC)cc(C(=O)NCC(C)Oc2ccccc2)c1 +CC(NC(=O)c1cccc(N(C)C)c1)C(=O)NCc1cscn1 +Cc1ccc(C(=O)NC(Cc2ccccc2)C(=O)N2CCCC2)s1 +COc1ccc(NC(C)=O)cc1NC(=O)N(C)Cc1ccoc1C +Cc1sc2nc(CSc3nncn3C)[nH]c(=O)c2c1C +Cc1cnn(C2CN(Cc3cn4c(C)cc(C)nc4n3)C2)c1 +COC(=O)C(NC(=O)C(C)Sc1ccccn1)C(C)C +Cc1cccc(NC(=O)CN(C)C(=O)C2CC3CCC2O3)n1 +CC(C#N)CN(C)Cc1csc(-c2ncccn2)n1 +COc1ccc(NC(=O)c2ccc[nH]c2=O)cc1NC(C)=O +Cc1ccccc1NC(=O)C(C)Oc1cccc(C#N)c1 +O=C(Nc1cc2c(cc1Cl)OCCO2)c1ccccc1F +CCc1nnc(NC(=O)CCOc2ccc(OC)cc2)s1 +CCc1ccc(C(=O)Nc2cnc3c(cnn3C(C)C)c2)cc1 +Cn1cc(NC(=O)c2nn(C)c3ccc(Cl)cc3c2=O)cn1 +CCN(CC(C)C)C(=O)Nc1ccc(OC)cc1OC +Nc1ccnc(Oc2ccccc2Br)c1 +CC(C)n1ncc2c(C(=O)NC3CC3)cc(-c3cccs3)nc21 +COc1ccccc1CSc1nnc(Cc2csc(C)n2)o1 +CCOc1ccc(NC(=O)COc2ccc(C(N)=O)cc2)cc1 +CCOC(=O)c1cncc(Nc2ccc(OC)cc2)c1 +O=C(CSc1cc(N2CCCCC2)ncn1)N1CCCCC1 +CC(C)CN(CC(C)C)C(=O)Nc1nncs1 +CCN(Cc1ccc2c(c1)OCO2)C(=O)C1CCC(=O)NC1 +COC(=O)c1sccc1NC(=O)NCc1ccncc1 +CCCC1CCC(NC(=O)CN(C)S(C)(=O)=O)CC1 +Cc1ncsc1CCC(=O)N1CCCC(c2cc(=O)[nH]cn2)C1 +CCNC(=O)CCn1nc(-c2ccccc2)c2ccccc2c1=O +O=C(Cn1ccc2ccccc21)N1CCc2ncncc2C1 +CCn1ccc(NC(=O)c2ccccc2OCc2nnnn2C)n1 +Cc1ccsc1CN(CCC#N)CCC(C)C +Fc1cc(Cl)c2c(c1)CCNC2c1ccccn1 +CCn1nnc(CO)c1COc1cccc(OC)c1 +CCCn1nccc1NC(=O)c1cc2ccccc2n1CC +COc1cccc(CN(C)C(=O)C(c2ccccc2)n2cccn2)c1 +CC(=O)c1cccc(S(=O)(=O)Oc2ccc(CC#N)cc2)c1 +CN(C)c1ncc(Br)c2c(N)ccc(F)c12 +Cc1ccc(NC(=O)CNC(=O)c2ccc3c(c2)OCO3)c(Cl)c1 +COc1cccc(OC)c1C(=O)NCc1cccs1 +O=C1NCCN(C(=O)Cc2ccc(F)cc2)C1c1ccccc1 +Cc1nnc2n1CC(NC(=O)Cn1c(=O)cnc3ccccc31)CC2 +CCc1ccc2occ(CC(=O)Nc3ccccn3)c2c1 +CC(=O)NC(C(C)C)C1NCCc2c(C)ccc(F)c21 +COC(=O)c1cccc(NC(=O)Cn2nnc(-c3ccccc3)n2)c1 +Brc1cccc(C2CN(CC3CCOCC3)CCO2)c1 +O=c1ccc(-c2ccco2)nn1Cc1ccccc1Cl +Cc1cc(-c2cccc(F)c2)nnc1N1CCOC(C(N)=O)C1 +COc1ccc(N)cc1CNC(=O)CCc1ccccc1 +CCCCCCn1cnc2c(cnn2-c2ccccc2)c1=O +c1ccc(CCc2n[nH]c(CN3CCOc4ccccc4C3)n2)cc1 +COc1ccc(NC(=O)c2cccc(C(=O)N(C)C)c2)cc1OC +Cc1nnc(-c2ccc(NC(=O)CCSc3ccccn3)cc2)o1 +CS(=O)(=O)N1CCN(C(=O)c2cc(Cl)cc(Cl)c2)CC1 +CCN(CC(F)(F)F)C(=O)Cn1cnc2c1c(=O)n(C)c(=O)n2C +NC(=O)c1n[nH]c2ccc(NC(=O)C3(c4ccccc4)CC3)cc12 +NS(=O)(=O)CCN1CCc2cc(Cl)cc(Cl)c2C1 +COc1cccc(C(=O)Nc2ccc(S(N)(=O)=O)cc2F)c1 +O=C(NCCNS(=O)(=O)Cc1ccccc1)Nc1cccnc1 +Cc1cc(Nc2ncnc(Oc3cccnc3)c2N)no1 +CC(NC(=O)Nc1nccs1)c1ccc(N2CCCC2=O)cc1 +CC(C)N(C(=O)Cn1c(=O)cnc2ccccc21)C(C)C +Cc1ccc(CNC(=O)C(C)NC(=O)c2ccccc2)cc1 +O=C(C1CCCC1)N1CCC(c2nc(-c3ccncc3)cs2)CC1 +O=C(Nc1ncc(Cl)cc1Cl)c1csnn1 +O=C(Nc1ccccc1)C1CCCN(C(=O)c2cccc3ccoc23)C1 +O=C(NC1CCN(c2nnc(C3CCC3)o2)C1)OCc1ccccc1 +CC(c1ccccn1)N(C)S(=O)(=O)c1ccc(F)c(F)c1F +CC(C)(C)OC(=O)NCc1cc(F)ccc1Br +O=C(NCc1ccccc1F)Nc1cccc(F)c1F +COCCc1noc(C2(c3ccc(F)cc3)CC2)n1 +CCS(=O)(=O)c1ccc(O)c(NCCC#N)c1 +C=CCNC(=O)CSc1nc(-c2ccccc2)ns1 +CCc1nc(C2CCCN2C(=O)c2cccc3c2OCCO3)no1 +Cc1nsc(N2CCN(c3cnn(C)c(=O)c3Cl)CC2)n1 +COC(=O)CCC(=O)N(C)Cc1ccc(OC)cc1 +Cc1ccc(NC(=O)CCN2C(=O)C(C)Oc3ccccc32)cc1 +Cc1cc(N)ccc1S(=O)(=O)N1CCCC(C)C1 +CCCNC(=O)c1ccc(CN2CCOCC2)cc1 +O=C(NC1CC1)c1ccc(NC(=O)c2cncn2-c2ccccc2)cc1 +CCC(=O)N1CCCN(C(=O)Nc2ccc(-c3cc[nH]n3)cc2)CC1 +CCOc1nnc(CN2CCCCC2Cn2cc(C)cn2)s1 +O=C(NCc1ccc2c(c1)OCO2)c1ccc2c(c1)CNCC2 +CCC1CCCN(C(=O)CCCNC(=O)c2cccs2)C1 +CC(=O)NCCCCCC(=O)N1CCCc2cc(F)cc(C)c21 +O=C(COc1cccc(Br)c1)NCc1ccccc1F +Cc1cc(NCc2cc(Cl)c3c(c2)OCCCO3)n2ncnc2n1 +COc1ccc(C(=O)NC2CCC2)cc1Br +CCC(=O)NC1CCCN(C(=O)NC(C)c2ccc(C)c(F)c2)C1 +COC(=O)c1ccc(NC(=O)c2cc(C)nc(SC)n2)cc1 +CCC1CCCCC1OC(=O)CCn1nnc2ccccc2c1=O +Cc1ccc(CN2CCN(C(=O)c3cc(C(C)C)no3)CC2=O)cc1 +CC1CCCCN1C(=O)C1COc2ccccc2C1 +[H]N=c1n(CCOc2ccccc2)c2ccccc2n1C(C)C +Cc1nn(-c2ccccc2)c(C)c1C(=O)NCC1CCCO1 +O=C(Cn1ncc2c1-c1ccccc1OC2)Nc1ccccc1Cl +CCn1ccc2cc(NC(=O)CN(C)c3ccc(C#N)cn3)ccc21 +COCCOCC(=O)N1CCC(Oc2c(C)cccc2C)CC1 +Cc1ccc(C)c(OC(=O)C2CCN(c3cnccn3)CC2)c1 +C=CCNC(=O)CNc1cccc(C(=O)N2CCCCC2)c1 +Cc1ccc(NC(=O)C(C)Sc2nc(C)c(C)o2)cc1C +CCn1c(C)cc(C(=O)NC2CCCCC2C)c1C +O=C(Nc1cccc(C(F)(F)F)c1)c1cccc(C(F)(F)F)n1 +COc1ccc(F)cc1NC(=O)c1cccc(C)c1F +Cc1cc(C(=O)COC(=O)c2ccco2)c(C)n1C +CC(c1nc2ccccc2s1)N(C)C(=O)c1ccccc1F +C=CCn1nnnc1NCc1c(OCC)ccc2ccccc12 +Cn1cc(C(=O)N(Cc2ccc(C(F)(F)F)cc2)C2CC2)cn1 +Cn1nc(C(C)(C)C)cc1C(=O)Nc1ccc(F)c(C#N)c1 +Cc1cccc(N(C(C)C(N)=O)S(C)(=O)=O)c1 +CC(C)n1ccc(C(=O)Nc2nc3c(s2)CN(C)CC3)n1 +COC(=O)c1ncn(Cc2cc(Cl)cc3cccnc23)n1 +CC(=O)Nc1ccc(O)c(C(=O)NCc2cccnc2)c1 +COc1cccc(CNC(=O)NC2COc3ccc(OC)cc3C2)c1 +CCCCN(C)C(=O)C(C)Sc1ccccn1 +Cc1cccc(NC(=O)Nc2ccc(Cn3cncn3)cc2)c1C +CC(C)N(C)S(=O)(=O)c1ccc(C(=O)N2CCCC(O)C2)cc1 +COc1ccc(C(=O)N2CCC3(CC2)OCCCO3)cc1F +Cc1ccc(C)c(NC(=O)CN(C)c2ncccn2)c1 +CC(CNC(=O)C(C)CC1CCCC1)Cn1cccn1 +CN(C(=O)C1CCCCC1)C(C#N)c1cccnc1 +CNC(=O)c1cc(S(=O)(=O)N2CCc3ccccc32)cn1C +CCC(NC(=O)c1ccc(F)nc1)c1nc2ccccc2[nH]1 +O=C(CCC(=O)N1CCN(c2ccccc2)CC1)N1CCOCC1 +Cc1cc(OC(C)C(=O)NC(C)CO)ccc1C(C)C +O=C1COc2cc(C(=O)NCCOc3ccc(F)cc3)ccc2N1 +CCn1nnnc1-c1cccc(C(=O)N2CCc3ccccc3C2)c1 +Cc1cc(NC(=O)C2CSc3ncc(C)c(=O)n3C2)sn1 +COc1ccc(N2CCCC(C(=O)NC(C)C)C2)nn1 +CN(C)C(=O)c1ccc(CS(=O)(=O)c2ccccn2)cc1 +CN(Cc1ccsc1)C(=O)NCc1cc[nH]n1 +C=CCN(Cc1ccccc1Cl)C(=O)CCNC(C)=O +Cc1nn(Cc2ccc(Cl)cc2)c(C)c1CN(C)CC(F)F +Cc1nnsc1-c1nnc2sc(-c3cnccn3)nn12 +CC(O)CN1CCN(CC(=O)Nc2cccnc2)CC1 +CCC(C)C(C)(O)CNC(=O)c1ccc(Br)cc1 +N#Cc1ccc(-c2noc(C3(C#N)CCCCC3)n2)nc1 +COc1ccc(CCNC(=O)N2CCCC2CO)c(Cl)c1 +Cc1cc(CNC(C)c2ccc(S(C)(=O)=O)c(F)c2)no1 +Cc1noc(CN2CCN(Cc3nnc(-c4ccco4)o3)CC2)n1 +Cc1cccc(N2CCN(C(=O)C3CCCC3)CC2)c1 +Cc1ccc(N2CC(c3nc(-c4ccccc4)no3)CC2=O)cc1F +Cc1cc(C(=O)Cn2cnc3c2c(=O)n(C)c(=O)n3C)c(C)s1 +COc1cccc2ncn(C(C)Cc3cccc(C)n3)c(=O)c12 +Cc1nn(C)c(C(=O)Nc2ccn(C)n2)c1Br +CCC(C(=O)OCC(C)C)n1c(C)ccc(C(C)=O)c1=O +CCC(=O)Nc1cccc(NC(=O)CNc2ccccc2F)c1 +CCCC(C)N(C)C(=O)Nc1ccc(S(C)(=O)=O)cc1 +CC1CCCN(C(=O)CNc2ccc(-c3nnnn3C3CC3)cc2)C1 +O=C(Nc1ncccc1OCc1ccncc1)c1ccccn1 +CC1CC1c1ccc(CCC(=O)N2CCC(C(N)=O)CC2)o1 +CCN(CC)C(=O)CCC(=O)Nc1nc(-c2ccco2)cs1 +CN1CCN(C(=O)C2CCN(c3ccc(Cl)cc3F)C2=O)CC1 +CC(=O)Nc1ccc(C)c(NC(=O)N(C2CC2)C(C)C2CC2)c1 +COc1ccccc1OCC(=O)Oc1ccccc1OC +CC(=O)N1CCC(C(=O)N2CCc3sccc3C2)CC1 +CC(C)c1cc(C(=O)NCCSc2ncn[nH]2)n(C)n1 +O=C(NCCc1ccccc1)NC1CCN(C(=O)c2ccco2)CC1 +COC(=O)CNS(=O)(=O)c1ccc(C(=O)OC)cc1 +CC1CN(CC(=O)NCC2CCCO2)c2c(N)cccc2O1 +CCc1cccc(NC(=O)COc2cccc(C(C)O)c2)c1 +CC(C(=O)NCc1cccnc1Oc1ccccc1)N1CCCC1=O +COC(=O)CSc1nnc(-c2ccccc2)o1 +CC(C)CC1CNC(c2ccccc2)CN1S(C)(=O)=O +Cc1ccc(C(=O)NCc2ccsc2-n2cccc2)o1 +CC(C)C(=O)N1CC(n2cc(COc3ccc(F)cc3)nn2)C1 +CC1(C)OC(=O)C(c2ccc3ccccc3n2)C(=O)O1 +CC(C)N1CC(C(=O)NCCOCc2ccc(Cl)cc2)CC1=O +CCC1CN(C(=O)c2cccn(Cc3cccc(C)c3)c2=O)CCO1 +CCc1ccc(C(=O)N(CCOC)CC(C)C)cc1 +CC1CN(C(=O)c2ccc(S(=O)(=O)N3CCCC3)cc2)CCO1 +CCCOc1ccc(OC(=O)C2CCOCC2)cc1 +CC(C)NC(=O)Cc1nc2ccc(C(C)C)cc2c(=O)[nH]1 +COc1ccccc1CC(=O)NCc1ccc2c(c1)OCO2 +CNS(=O)(=O)Cc1ccc(CNC(=O)c2cccc(F)c2)cc1 +CCOc1cc(CNC(=O)c2cn(C)nc2C(F)(F)F)ccn1 +CC(C)CC(=O)NC1CCN(S(=O)(=O)c2cnn(C)c2)CC1 +CNC(=O)Cn1cc(-c2ccc(F)cc2Cl)cn1 +CCOc1ccc(-c2cc(N)c(=O)n(CCC(C)C)n2)cc1 +CCOc1ccc(C(=O)NCC(=O)NCc2ccc(F)cc2)cc1 +Cc1ccc(CC(=O)Nc2cc(-c3ccncc3)n[nH]2)cc1 +O=c1c2oc3ccccc3c2ncn1Cc1cnn(-c2ccccc2)c1 +Cc1cccc(OCCCC(=O)NCc2nc(C)sc2C)c1 +C=CCNC(=O)N(CCC(N)=O)Cc1ccccc1 +C#CCOC(=O)c1cccc(S(=O)(=O)N(C)C)c1 +COCCN(CC(=O)OC)C(=O)c1ccc(C)nc1 +Cc1ccc2oc(=O)c3cnn(CC(=O)N4CCCCC4)c3c2c1 +O=C(c1csc(COc2ccc(F)cc2F)n1)N1CCCC1 +CCCNC(=O)CNC(=O)NC1CCC(O)CC1 +CC(C)C(=O)Nc1ccc(C(=O)N2CCN(CCO)CC2)cc1 +COc1ccc(NC(=O)C2CC(=O)N(C(C)C)C2)cc1 +CS(=O)(=O)c1ccc(C(=O)OCc2ccccn2)cc1 +O=S(=O)(NCc1ccccc1-n1ccnc1)c1ccc(F)cc1 +CCOC(=O)c1c(C)[nH]c(C(=O)NCc2cccnc2)c1C +Cc1csc(C(N)c2c(Cl)cccc2Cl)n1 +C#CCN(CC)c1c(N)n(CCCC)c(=O)[nH]c1=O +COCCNC(=O)Cc1ccc(Cl)cc1Cl +Cc1ccc(N)cc1NC(=O)C(C)Sc1cccs1 +C=CCN(CC=C)C(=O)CSc1ccc(Br)cn1 +Cc1nc2cc(NC(=O)Cn3cccn3)ccc2s1 +COc1ccc(NC(=O)C2CC2)cc1-n1cnnn1 +Cc1nc(C)c(CNC2(c3ccc(F)cc3F)CCOCC2)s1 +C#CCOc1cccc(NC(=O)c2cnn(-c3ccncc3)c2C)c1 +O=C(NCc1cc2ccccc2o1)N1CCOCC1 +CC(C#N)CN(C)CCOc1ccc(CC#N)cc1 +CC(C)Cc1nc(C(=O)NC(C2CC2)C2CC2)cs1 +CN(C(=O)Nc1nc(-c2ccco2)cs1)C1CC1 +CC(=O)Nc1cc(C(=O)Nc2cccnc2-n2cccn2)ccc1F +CCc1noc(CC)c1CC(=O)Nc1ccc(C)c(C(N)=O)c1 +CC(=O)c1ccc(Oc2ccc(C(=O)NCc3ccn(C)c3)cc2)cc1 +Cc1noc(C2CCN(C(=O)Nc3nccs3)CC2)n1 +CCCCCn1c(N2CCOCC2)nc2c1c(=O)[nH]c(=O)n2C +COC(=O)c1ccc(CS(=O)(=O)c2ccc(F)cc2)o1 +C=CCn1nnnc1NCc1cc(Br)ccc1OC +Cn1nnnc1Sc1ccc2nnc(C(F)(F)F)n2n1 +CCOC(C)c1ccc(-c2ccc(-n3cnnc3)nc2C)cc1 +Cn1cnnc1CCNC(=O)c1cc(-c2ccc(F)cc2)on1 +CC(C)c1nnc(-n2nnc(C#N)c2C(C)(C)C)s1 +O=C(NCc1ccc(Cn2cccn2)cc1)c1cc(F)ccc1F +N#CCS(=O)(=O)c1ccc(C(=O)CCC2CCCCC2)cc1 +Cc1cc(C)c(NC(=O)COCC(F)(F)F)c(C)n1 +Cc1nn(C)c(C)c1C(=O)Nc1ccc2[nH]nc(C(N)=O)c2c1 +CC(C)Nc1cccc(CNC(=O)c2ccco2)c1 +COCCCOc1ccccc1NC(=O)c1ccc(=O)n(C)n1 +COc1cc(C)c(NC(=O)C(C)(C)C)cc1OC +C=CCNC(=O)CCn1nnc2cc(S(=O)(=O)N(C)C)ccc21 +COC(=O)c1cccc(OC(=O)CCc2c(C)nn(C)c2C)c1 +CCc1nnc(N2CCC(N3CCOC3=O)CC2)o1 +CNC(=O)C1CN(Cc2ccc3c(c2)OCCO3)c2ccccc2O1 +Cc1csc(N(C(=O)c2cccc(-c3ccoc3)c2)C2CC2)n1 +Cc1cc(CNC2CCc3c(ccc(=O)n3CC3CC3)C2)oc1C +Cc1cccc(C)c1NC(=O)CNc1ccccc1F +CC(=O)Nc1ccc(OC(C)C(=O)Nc2cccc(F)c2)cc1 +Cc1ccc(OC(C)C(=O)NCCCC(N)=O)cc1 +COc1ccc(CNC(=O)COc2nnc3ccccn23)cc1 +Cc1ccc(N2C(=O)CCS2(=O)=O)cc1S(=O)(=O)NC(C)C +CC(C)(O)Cn1nc(-c2ccc(F)c(F)c2)c2ccccc2c1=O +O=C(NCc1ccncc1)Nc1cccc(N2CCCCC2)c1 +O=C(c1cc2c(s1)CCC2)N(CCO)C1CCCC1 +CN(CCOC(=O)c1ccccc1)C1=NS(=O)(=O)c2ccccc21 +O=C(Cc1cccc(F)c1)NCC(=O)OCC(F)(F)F +CCc1cc(N)c2onc(CC(=O)N(CC)CCO)c2c1 +O=C(NCc1ccco1)C1CCCN1C(=O)c1cccc(F)c1 +CC(C)NC(=O)NCCc1ncc(-c2ccccc2)[nH]1 +CNC(=O)c1sc(C2CN3CCCC3CO2)nc1C +CCCCNC(=O)Cc1noc2c(C)cc(N)cc12 +COc1ncc(C)cc1C1CCN(C(=O)OC(C)(C)C)C1 +Cc1cc(C(C)Nc2ccc3nnnn3n2)c(C)o1 +CCC1(CC)CN(C(=O)C2CC(=O)N(Cc3ccncc3)C2)CCO1 +Cc1nc2ccccc2c(=O)n1CC(=O)N1CCC1 +Cc1nc(N(C)C)cc(N2CCN(C(=O)c3ccccc3)CC2)n1 +CC(=O)c1cccc(S(=O)(=O)N2CCN(C(C)=O)CC2)c1 +CC(=O)c1cccc(NC(=O)c2cncc(N)c2C)c1 +N#CC1(C(=O)Nc2ccc(CN3CCOC3=O)cc2)CCCC1 +Cc1nn2c(S(=O)(=O)N3CCC(C)CC3)c(C)nc2s1 +O=C(C1CCOc2ccccc2C1)N1CC(c2cccnc2)C1 +COCC(=O)NC1CC(C)(C)Oc2ccc(C)cc21 +CC(=O)N1CCN(C(=O)C(C)NC(=O)c2ccccc2Cl)CC1 +COC(=O)c1cc(C(=O)OC)cc(-c2ccc(C(C)=O)o2)c1 +Fc1ccc(C(CC(F)(F)F)NCc2csc(C3CC3)n2)cc1 +CC(NC(=O)Nc1ccc(F)c(C#N)c1)C(=O)NC(C)(C)C +Cc1ccnc(C2CCN(S(=O)(=O)N(C)C)C2)n1 +COCc1cc(C(=O)OCC(=O)N2CCc3ccccc32)ccc1F +Cc1cccc(OC(C)C(=O)N2CCNCC2)c1C +Cc1ccc(N(C)C(=O)c2cncn2-c2ccccc2)c(C)c1 +Cn1cc(CN2CC3CCCOC3C(NS(C)(=O)=O)C2)cn1 +Cc1ccccc1CCNC(=O)CN1CCN(C(=O)C2CC2)CC1 +Cc1cc(C(C)NC(=O)N(C)Cc2ccccn2)c(C)s1 +Cc1c(C(=O)N2CCCc3cccc(OC(F)F)c32)cnn1C +Cc1nnsc1C(=O)N1CC(O)C(N2CCC(F)(F)CC2)C1 +O=C(Nc1ccccc1)Nc1cnn(C2CCOCC2)c1 +CC1(C)C2CCC1(C)C(NC(=O)N1CCNC(=O)C1)C2 +COc1ccccc1CCC(=O)N1CCCc2c(cnn2C)C1 +CC(C)NC(=O)CN(C)C(=O)CCc1ccsc1 +O=C(Cn1nc(C(F)(F)F)c2c1CCCC2)NCc1cccs1 +Cc1ncsc1CCNCc1ccc(F)c(F)c1 +CCc1nnc(NC(=O)c2ccc(OCC(F)(F)F)nc2)s1 +Cn1cc(-c2nn(-c3ccc(F)cc3)c3c2CNCC3)nn1 +CC(=O)c1cc(-c2ccc3c(c2)OCCCO3)oc1C +Cc1ccc(OCc2nc(CC(=O)NC(C)C)cs2)cc1 +CCS(=O)(=O)c1ccc(C2COCC(C)N2)cc1 +COc1ccc(Cl)cc1CN1CCN(C(=O)c2ccccn2)CC1 +Cc1cc(CN2CCN(c3ccnc(-c4ccccc4)n3)CC2)no1 +Cc1nc(CSc2nnc(-c3ccco3)o2)cc(=O)[nH]1 +Cc1cc(C)c2c(-n3cccc3)nn(CC(=O)NCc3ccco3)c2n1 +CCC(C)N(Cc1ccccc1)S(=O)(=O)c1cn(C)c(C)n1 +Cc1nc(NC(=O)Nc2ccc(Cl)cc2)sc1C +CC(C)C(=O)NCC1CCN(C(=O)c2ccoc2)CC1 +O=C(NCc1nc2ccccc2s1)c1ccc(-n2cncn2)nc1 +Cc1cc(=O)[nH]c(SCC(=O)Nc2nnc(C)s2)n1 +Cc1noc(C)c1C(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1 +COc1ccc2c(c1)OCC(CNC(=O)c1ccncc1)C2 +COc1ccc(F)cc1NC(=O)NCC(=O)NC1CC1 +COc1cccc(N2CCC(CNC(=O)Cc3ccccc3)C2)c1 +Cc1nn(C)c(C)c1CNC(=O)c1cc(-n2cnnn2)ccc1Cl +O=C(c1cc(=O)c2ccccc2o1)N1CCc2ncncc2C1 +CC(C)Oc1cc(CNS(=O)(=O)C2Cc3ccccc3C2)ccn1 +COc1ccc(Cc2nc(C)cc(N)n2)cc1C(C)C +COCCCNC(=O)C1CC(=O)N(Cc2ccccc2F)C1 +CSc1ccccc1C(=O)Nn1cnc2ccccc21 +CCOCC(=O)C(C#N)c1nc2sc3c(c2c(=O)[nH]1)CCCC3 +COCC1CCCN1C(=O)NCc1cccc(NC(C)C)c1 +COc1cccc(OCC(=O)Nc2ccc3c(c2)C(=O)NCC3)c1 +COCCn1nc(C(=O)NCc2ccccn2)ccc1=O +C#Cc1cccc(N(C(=O)c2cccc(C#N)c2)C(C)C)c1 +CC(C)(C)C(=O)COC(=O)c1ccc(Cl)cc1N +COc1ccc(C)cc1C(C#N)Cc1ccc2c(c1)OCCO2 +Cc1cnc(C(=O)N(Cc2cccnc2)Cc2ccco2)cn1 +CC(Sc1ncn[nH]1)C(=O)NC1CCCCCC1 +CC(NC(=O)N1CCOCC1C1CC1)c1ccc(C#N)cc1 +N#CCCN(Cc1c(F)cccc1N1CCCC1)CC1CC1 +O=C(CSc1ccccn1)N1CCN(c2cnccn2)CC1 +COc1ccc(CN2CCN(C(=O)c3cnc(C)cn3)CC2)cc1F +Cn1nc(NC(=O)C2CCCCC2)c2cccnc21 +CCc1ccc(N)cc1S(=O)(=O)NCCCOC +Cc1ccccc1CN(C)C(=O)CNC(=O)c1ccccc1C +Cc1c(N)cccc1N1CC(=O)Nc2ccccc21 +Cc1cc(CCC(=O)NC2(C#N)CC2)ccc1Br +Cc1cccc(C)c1OC(=O)C1CC(=O)N(CC(F)(F)F)C1 +CC1CCCCN1C(=O)Cc1cc(-c2ccc3c(c2)OCO3)on1 +O=S(=O)(c1ccc2c(c1)OCO2)N1CCOCC1 +CC(CN1CCOCC1)NC(=O)c1cc(N)ccn1 +Cc1cc(NC(=O)c2ccc(OC(C)c3ccccc3)nc2)n(C)n1 +C#CCN1CCN(C(=O)NCCOc2ccccc2)CC1 +N#CCCn1cc(-c2ccnc(N3CCCC3)n2)c2ccccc21 +COc1ccc(CC(C)CNC(=O)C2CNC(=O)C2)cc1 +O=C(c1cc(Cl)c[nH]1)N1CCC(OCCc2ccccc2)CC1 +CCOc1cccc(CC(C#N)C(=O)N2CCCC2)c1 +O=C(Cn1ncc2cccn2c1=O)c1ccc(F)cc1 +CCCCNC(=O)CSc1nc(N)cc(N)n1 +COc1ccc(OCC(=O)NCC(O)c2c(F)cccc2F)cc1 +CCN(CC)c1nc(C)cc(C(=O)Nc2nc(C)c(C)s2)n1 +CCn1nc(C)c(NC(=O)N(Cc2ccccc2)CC(C)(C)O)c1C +Cc1ccc(N2CCn3c2nc2c3c(=O)[nH]c(=O)n2C)cc1Cl +CCC(NC(=O)c1ccncc1)C(O)c1ccc(C(F)(F)F)cc1 +O=C(CC1CC1)N1CCC2(CCCN(Cc3ccc(F)cc3)C2=O)C1 +COc1ccc(-c2ccnc3nc(SC)nn23)cc1 +COc1ccc(S(=O)(=O)Nc2cccc(-c3nnnn3C)c2)cc1 +O=c1ccc2c([nH]1)CCN(S(=O)(=O)c1ccc3c(c1)CCCC3)C2 +O=c1[nH]cnc2ccc(-c3cnn(-c4ccccc4)c3)cc12 +CC(=O)c1ccc(NC(=O)NCCc2cn3ccccc3n2)cc1 +CCCCSc1ccc(NC(=O)c2cccnc2)cc1 +COc1nn(C)c2c1CCCN(S(=O)(=O)c1cccc(F)c1)C2 +CC(=O)Nc1cc(NCc2cn(C)nc2-c2cccnc2)ccc1F +Cc1ncsc1C(=O)NC1CCN(c2c(F)cccc2F)C1=O +O=C(CNC1=NS(=O)(=O)c2ccccc21)NCCc1cccs1 +COc1ccc(NC(=O)c2ccc3nnc(C)n3c2)cc1 +COc1ccc(-n2cc(CNS(=O)(=O)N(C)C(C)C)nn2)cc1 +O=C1CC(c2ccncc2)C2(CCN(C(=O)c3ccc[nH]3)CC2)N1 +CCc1cc(NC(=O)c2cnn(C(C)C)c2C(F)(F)F)[nH]n1 +COc1c(C(=O)NCc2ccco2)nnn1Cc1ccccc1 +CC(=O)NC(C)C(=O)Nc1ccc2nc(C)sc2c1 +CCOC(=O)NCCC(=O)Nc1ccc2c(c1)CCC2 +N#CC(NC(=O)CNC(=O)OCc1ccccc1)c1ccccc1F +COCc1cccc(NCc2cccc(C(N)=O)c2)c1 +CNC(=O)Nc1cccc(NC(=O)CNc2ccccc2OC)c1 +CCC(CC)NC(=O)c1cc(COc2ccc3ncccc3c2)on1 +COC(=O)C(C)CS(=O)(=O)c1ccc(F)cc1 +CCc1onc(C)c1NC(=O)CSc1nc(C)cc(C)n1 +CC(NC(=O)c1cc[nH]n1)c1ccc(Cl)c(Cl)c1 +CNC(=O)c1ccc(CNC(=O)COc2ccccc2OC)cc1 +CC(C)c1nc(CNCCc2cccs2)cs1 +CCc1nc(CN(C)C(=O)NCC2CC2C)cs1 +CC(=O)NCCCCCC(=O)N1CCNC(=O)C1 +CC(C)N(CCC#N)C(=O)CCc1ncc(-c2ccccc2)o1 +CCN(Cc1ccccc1)C(=O)c1ccc(C#N)cc1 +Cc1nnnn1C(Cc1cccc(F)c1)C(=O)N(C)CC1CC1 +CSc1nnc2n1-c1sc3c(c1-c1ncnn1-2)CCC(C)C3 +COc1cc(Cl)ccc1S(=O)(=O)N(C)CCO +O=C(Nc1cccc(N2CCCCC2=O)c1)c1ccoc1 +COC(C)(C)c1noc(-c2cccc(COc3ccc(C)nc3)c2)n1 +CC(C)CCNC1=NS(=O)(=O)c2cc(N(C)C)ccc2N1 +Cn1ccc(NC(=O)CNC(=O)c2ccc(N3CCCC3=O)cc2)n1 +CC(C)(C)OC(=O)N1CCC(CCOc2cc(C#N)ccn2)CC1 +O=C(Cc1ccc(F)cc1F)N1CCCC(N2CCCC2=O)C1 +CCn1c(CNc2ccccc2C#N)nc2ccccc21 +Cc1ccc(CN(C)C(=O)Nc2ccc(OCC(N)=O)cc2C)s1 +CC(C)NS(=O)(=O)c1cccc(C(=O)Nc2cccn(C)c2=O)c1 +Cc1ccc(O)c(C(=O)NCc2ccc(NC(=O)C3CC3)cc2)c1 +CC(C)CC1COCCN1C(=O)CNC(=O)CCC1CCCC1 +COc1cc(OC)cc(C(=O)N2CCN(c3ccccc3C)CC2)c1 +CCC(C)N(C)C(=O)CCSc1ccccc1 +O=C(Nc1ccc(Br)c(Br)c1)c1nc[nH]n1 +Cn1cc(C(=O)NC2CCc3ccccc32)c2ccccc21 +O=S(=O)(NC1c2ccccc2CC1O)c1ccc(F)c(F)c1 +Cc1ccccc1CN(C)C(=O)C(C)Nc1ccn(C)n1 +CCc1nc(CNc2ccccc2NC(=O)c2ccccc2)no1 +C#CCn1c(=O)nc2n1C(=O)N(c1cccc(OC)c1)C2 +COc1ccccc1CNC(=O)c1ccc(C)c(N)c1 +Cc1cc(C)c(C)c(OC(C)C(=O)N2CCCC2)c1 +CN(Cc1ccsc1)C(=O)c1cccc(-c2ccoc2)c1 +Cc1cc(NC(=O)Cn2cc(Br)c(C)n2)no1 +CCCOc1ccc(CNC(=O)c2cc(C)ccc2F)cn1 +Cc1ccc(CC(=O)NCc2ccc(C)n2C)cc1 +Cc1nn(C(C)C(=O)NC(C)c2ccccc2)c2ccccc12 +CCN(C(=O)c1nn(-c2ccccc2)c(=O)c2ccccc12)C1CC1 +Cc1sc2nc(Cc3ccccc3)nc(NCCO)c2c1C +CC1C(=O)Nc2c1cc(Br)cc2C(O)C(C)C +Cc1cc(C)c(NC(=O)C(C)Sc2ccccn2)c(C)c1 +Nc1ccc2onc(CC(=O)Nc3cccc(Cl)c3)c2c1 +NC(=O)c1ccc(-c2nnn(Cc3ccc(Cl)cc3Cl)n2)cc1 +Cn1cc(-c2noc(-c3n[nH]c4ccccc34)n2)ccc1=O +CC(C)Cc1cc(Br)c2oc(=O)[nH]c2c1 +CN(CCOCC1CC1)S(=O)(=O)c1ccc2c(c1)CCC2 +CC1CCCN(S(=O)(=O)N2CCCC(CCO)C2)C1 +O=C(Nc1cc(Cl)ccc1F)N1CCCC(O)C1 +COc1ccc(-c2nsc3c2NC(=O)CC3c2ccsc2)cc1 +CCCn1nnnc1COC(=O)c1c(C)nsc1NC +CCc1ccccc1OCC(=O)NCc1cnc(C)s1 +COC(=O)c1ccc(COc2cccc(C(C)=O)c2)cc1F +CC(=O)Nc1ccc(Nc2ncccc2C(N)=O)cc1 +CC(NC(=O)C(C)Oc1ccc(-c2ccccc2)cc1)C(N)=O +O=C(Cn1ccccc1=O)Nc1cccc(Oc2ccccn2)c1 +CCNC(=O)CNC(=O)c1cc(C)nc(SCC)n1 +CCCNC(=O)c1ccc(NC(=O)CCn2ccccc2=O)cc1 +CC(C)C(=O)NCc1noc(-c2ccc(F)cc2)n1 +COc1ccc(-c2nnc(SC(C)C#N)n2N)c(OC)c1 +Cc1cc(C)cc(NC(=O)NC2CC3C(=O)NC(CO)C(=O)N3C2)c1 +COc1cccc(NC(=O)C(C)Oc2cccc(F)c2)c1 +Cc1cc(C(=O)N2CCCCC2CCc2ccc(O)cc2)cc(=O)[nH]1 +NC(=O)Nc1cccc(C(=O)NCC2CCCCO2)c1 +Cc1nnc(NC(=O)C2CCN(c3ncccn3)CC2)s1 +CN(C)c1ccc(-c2noc(C(=O)NCc3cccs3)n2)cc1 +COc1ccc(C(=O)NCCc2csc(-c3cccnc3)n2)cc1 +CCc1c(NCc2cnn(C)c2C)cnn1CC(C)C +Cc1ccc(C(=O)NCc2c(C)nn(Cc3ccccc3)c2C)cc1 +COc1ccccc1CNC(=O)COC(=O)c1ccc(F)cc1F +OCCn1nnc(CO)c1-c1ccc(Cl)cc1 +Cc1cccc(-c2nc3cnccn3c2NCCC(=O)N(C)C)c1 +COc1cccc(OC)c1C(=O)Nc1cc(N)ccc1C +Cc1ccc(C2(O)CCN(c3ccnc(C)n3)C2)cc1 +COC(=O)c1c(NC(=O)Cc2cccs2)sc(C)c1C +Cc1oc2nc[nH]c(=O)c2c1C(=O)NCc1ccccc1F +CS(=O)(=O)NCCN1CCN(C(=O)c2cccs2)CC1 +CC(C)c1nnc(NC(=O)CSc2ccccn2)s1 +N#Cc1ccc(C(F)(F)F)nc1NC1CCCN(C(N)=O)C1 +COCC(=O)NCC(C)(OC)c1cccc(Cl)c1 +CC(=O)c1cc(-c2ccc3c(c2)ncn3C)[nH]c1C +c1ccc2[nH]c(-c3ccc(-n4ccnc4C4CCOC4)cc3)nc2c1 +Cc1ccc(C)c(OCC(=O)Nc2cccc(CO)c2)c1 +O=C(Cc1csc(-c2ccccc2F)n1)Nc1nccs1 +Cn1c(=O)n(CC(=O)NCc2ccccc2)c2ccccc21 +CCOc1ccccc1C(=O)Nc1ccc2c(c1)CCC(=O)N2 +Cc1ccc(OCc2occc2C(=O)Nn2cnnc2)cc1 +CC(Sc1ccccn1)C(=O)NCc1ccc(-n2ccnc2)nc1 +O=C(CNC(=O)c1cccs1)Nc1ccccc1N1CCCCC1 +CCN(Cc1ccccc1)C(=O)CNC(=O)NC(C)C +CC(C)CNC(=O)Nc1cnc2c(cnn2C(C)C)c1 +COCC(=O)N(C)CC(=O)N1CCCC1c1ccc(C(C)C)cc1 +Cc1ccc(-n2cccc2)c(C(=O)NC2CCN(C(N)=O)CC2)c1 +COc1ccc(Cl)cc1NC(=O)COC(=O)c1ccc(C)nc1 +CC(=O)Nc1cccc(C(=O)Nc2ccccc2SC(F)F)c1 +CC(OC(=O)CCNC(=O)c1ccsc1)c1ccccc1 +O=C(Cc1nc2ccccc2o1)NCCN1CCCc2ccccc21 +CNC(=O)C1CCC(NC(=O)c2cncc(Br)c2)CC1 +Cc1ccc2c(CC(=O)NCc3cccnc3-n3cccn3)coc2c1 +Cc1cn2c(CN(C)C(=O)c3cnc(N)c(Cl)c3)c(C)nc2s1 +O=C(NCCCN1CCCC1=O)Nc1ccc(F)cc1Cl +O=C(NCC(O)c1cc2ccccc2s1)c1cc(Cl)c[nH]1 +CC(O)c1c[nH]c2ccc(S(=O)(=O)N3CCCC3)cc2c1=O +Fc1cc(CN2CCN(CC(F)F)CC2)c2ncccc2c1 +CCC(C#N)NC(=O)C(C)Oc1ccccc1Cl +O=C(Cn1cccn1)N1CCN(Cc2ccc3c(c2)CCO3)CC1 +O=S(=O)(Nc1ccccc1)c1ccc(F)c(Cl)c1 +CCCCNC(=O)C(O)c1ccc2c(c1)OCCO2 +COc1ccc(OCC(=O)N2CCOC(C)(C)C2)cc1 +CCN(CC)C(=O)c1csc(Nc2nc(C)cc(C)n2)n1 +CC(O)Cn1c(-c2cccs2)nc2ccccc21 +Cc1ccccc1CN(C)C(=O)COn1nnc2ccccc21 +COc1ccc(OC(=O)c2cnc3n(c2=O)CCS3)cc1 +Nc1cc(-n2cnc3ccccc32)nn1-c1ccccc1 +Cc1nn(CCC(=O)NCCc2ccc(O)cc2)c2ccccc12 +Cc1cccc(CNC(=O)Nc2ccc3c(c2)NC(=O)C(C)O3)c1 +C=CCN(CC=C)C(=O)c1cc2ccccc2c(=O)[nH]1 +Cc1ccc(-c2nnc(CC(=O)NCc3ccc(F)cc3)o2)cc1 +c1csc(Cc2nc3c4c(ncn3n2)CCC4)c1 +CCc1noc(CC)c1CC(=O)Nc1cccc(N2CCCC2=O)c1 +COc1cc(CNC(=O)CNC(=O)C2CC2)ccc1C +Cc1nc(C(F)(F)F)ccc1C(=O)NCCc1ccc(O)cc1 +CCCC1CN(C(=O)Nc2sccc2C(=O)OCC)CCO1 +CCOc1ccc(N(C)S(=O)(=O)c2ccsc2C(N)=O)cc1 +CCCCN(CCO)C(=O)c1cccc(NC(C)=O)c1 +O=C(NCCc1ccc(-n2cccn2)cc1)c1cccs1 +Cc1cnc(C(=O)N2CCCC(CCc3ccc(F)cc3F)C2)cn1 +Cn1nc(CNC(=O)CCc2ccccc2)c2c1CCOC2 +Nc1ccccc1CC(=O)Nc1ccc(C(F)(F)F)cc1 +Cc1nc(-c2ccc(CC(=O)Nc3nc4ccccc4[nH]3)cc2)cs1 +CNC(=O)c1ccc(S(=O)(=O)NC(C(=O)N(C)C)C(C)C)cc1 +COc1ccc(C(=O)CCC(=O)Nc2cc(F)cc(F)c2)cc1OC +CCN(CC(=O)NC(C)C)C(=O)CSc1nnc(C)s1 +CCCn1cc(C(=O)NCc2c[nH]nc2-c2cccs2)c(C)n1 +CC(O)c1nc(C2CCOCC2)nn1C1CCCCC1 +N#CCOc1cccc(CC(=O)NC2CCCN(c3ccccc3)C2)c1 +CN(Cc1ccccc1)C(=O)c1ccc(NS(C)(=O)=O)cc1 +CS(=O)(=O)N1CCc2cc(C(=O)N3CCCCC3)ccc21 +CCn1cc(C(=O)Nc2ccccc2F)c2cccnc21 +CCc1cc(CC)n(-c2nc3c(c(=O)[nH]c(=O)n3C)n2CC)n1 +COc1cccc(NC(=O)NCc2cccc(C(N)=O)c2)c1 +CC(=O)c1cnn(-c2ccc(C(F)(F)F)cn2)c1C +Cc1ccc(CN2CCC(c3nc4ccccc4n3C)C2)o1 +Cc1nc(C)c(CC(=O)NC2CC2c2cccc(Cl)c2)c(=O)[nH]1 +CC1(C)COCCN1C(=O)c1cc(C(N)=O)n(-c2ccccc2)n1 +Cc1ccc(S(=O)(=O)Nc2cc(S(C)(=O)=O)ccc2C)cc1 +N#CCCN(Cc1ccco1)Cc1nnc(-c2ccc(Cl)cc2)o1 +COc1ncccc1NCc1ccc(Cl)cc1F +O=C(Nc1ccccc1)N(Cc1ccccc1)Cc1ccccn1 +CCOc1ccc(C(=O)CCC(=O)N2CCCCC2)cc1 +CC(C)Oc1cccc(CC(=O)Oc2cccc(S(C)(=O)=O)c2)c1 +c1ccc(OCCCn2nnc(-c3cccs3)n2)cc1 +O=C(C1CC1c1ccc(C(F)(F)F)cc1)N1CCC(CCO)C1 +COc1cc(CNC(=O)NC(C)C2CC2)ccc1C +Cc1[nH]c(S(=O)(=O)NCc2ccccc2)cc1N +COc1cccn(CC(=O)N2CCC(Cc3noc(C)n3)CC2)c1=O +Cc1cc(Cl)ccc1S(=O)(=O)NCCNC(=O)C1CC1 +CSc1ccc(C(O)CNC(=O)CCc2ccccc2)cc1 +CCOC(=O)c1c(C(F)(F)F)nc2nc(C)ccc2c1Cl +CC(NC(=O)NCC1CCC1)c1cc(F)ccc1N1CCC(O)CC1 +CCCOc1cc(C)ccc1NCc1csnn1 +CS(=O)(=O)N=c1[nH]ccc(OC2CC2)c1C(N)=O +CC(=O)c1ccc(NS(=O)(=O)c2ccccc2C#N)cc1 +CN(Cc1ccco1)C(=O)NCc1cccc(Br)c1 +N#CC(C(=O)C1(c2ccc(F)cc2)CCC1)c1ccccn1 +CC(C)(C)n1c(=O)c2cc(Cl)ccc2n1CC(N)=O +CC=Cc1ccc(OC(=O)Cc2c(C)noc2C)c(OC)c1 +C=CCN1C(=O)C(O)(c2c[nH]c3ccccc23)c2ccccc21 +Cn1c(C2CC2)nc2cc(NC(=O)Cn3ccccc3=O)ccc21 +Cc1ccccc1Cc1nnc2sc(C(C)C)nn12 +Cc1cnn(CCC(=O)N2CCCc3cc(C(C)C)ccc32)c1 +Cc1cc(N)ccc1NC(=O)Nc1ccc(C#N)cc1 +O=C(COCC1CC1)Oc1cccc(Cl)c1Cl +CCCS(=O)(=O)N1CCCC1c1cccc(N(C)C)c1 +O=C(NCc1ccc2c(c1)OCO2)c1cccc2ccoc12 +O=C(OCCc1cnccn1)c1ccn(-c2cccc(F)c2)n1 +O=C(Oc1ccccc1F)c1ccc(CN2CCCC2=O)cc1 +CCS(=O)(=O)N1CCN(C(=O)c2ccc(OC)cc2OC)CC1 +Cc1c(Cl)cccc1NC(=O)Nc1cccnc1 +CC(C)c1nnc2sc(-c3ccc4c(c3)CCN4)nn12 +COc1ccc2oc(C)c(C(=O)NCc3ccco3)c2c1 +Cc1noc(C)c1C(=O)NCc1ccnc(OCc2ccccc2)c1 +CCOC(=O)c1nn(C2CCCCC2)c(N)c1C +COc1ccccc1CC(C#N)C(=O)NC1CCCC1 +O=C(CCC(=O)c1ccccc1)Nc1ccc(-n2cccn2)c(F)c1 +CC1(c2ccccc2)CCC(=O)N(CCCCO)C1 +CN(Cc1ccsc1)C(=O)c1ccc(Br)cc1O +Cc1ccc(CC(=O)Nc2ccc(-c3cn4cccnc4n3)cc2)s1 +COc1ccc(CNC(=O)Cc2ccc3c(c2)CCCC3)cn1 +COc1ccc(CNc2c(C)cccc2O)c(F)c1 +CC(=O)Nc1ccc(NC(=O)COC(=O)c2ccc(Cl)cc2)cc1 +C=CCn1c(SCC(=O)c2ccc(C)cc2)nnc1C1CC1 +N#Cc1ccc(OCCn2c(-c3ccccn3)noc2=O)cc1 +CN(C)c1ncccc1C(=O)NC1C2CC3CC(C2)CC1C3 +Cc1c(NC(=O)c2ccnn2C)c(C(=O)N(C)C)nn1C +Cn1nnnc1-c1cccc(NC(=O)c2cccc(C(N)=O)c2)c1 +COCCCC(=O)Nc1ccccc1-n1cnnn1 +Nc1c(NCc2cccnc2)ncnc1Nc1cccc2ccccc12 +Nc1cc(N)nc(SCC(=O)Nc2c(Cl)cccc2Cl)n1 +NC(=O)C1CC(O)CN1C(=O)c1ccc(Br)cn1 +CC(=O)NC(C#N)c1cccc(Br)c1 +CCOC(=O)C1=C2C(=O)N=C(CN3CCCC(CC)C3)N=C2OC1C +COc1ccc(NCc2ccccc2C(N)=O)cn1 +CS(=O)(=O)N1CCC2(CC1)Cn1c(cc3ccccc31)C(=O)O2 +FC(F)Oc1ccc(CSc2nncs2)cc1 +COc1cccc(NC(=O)NCc2ccsc2)c1 +COc1ccc(-c2cc(C)nc3nc(N)nn23)cc1 +NC(=O)c1cc(Sc2ccccc2F)ccc1N +CN(CC#CCNS(C)(=O)=O)Cc1ccccc1 +CC(=O)C1Sc2nnc(-c3ccccc3)n2N=C1C +CC1CN(CCCC(N)=O)c2ccc(F)cc2N1 +CC(CO)NC(=O)c1ccccc1Oc1ccccc1 +CC1CCCC(C)N1C(=O)CSc1ncn[nH]1 +Cc1cccc(-n2nnc(C(=O)OC(C)C)c2N)c1 +COc1ccc2c(cnn2CCC(=O)NCc2ccco2)c1 +CN1C(=O)CCC(C(=O)NCC(=O)C(C)(C)C)C1c1cccc(F)c1 +Cn1ncc2c1CCCC2NC(=O)CCCC(=O)c1ccc(F)cc1 +Nc1cc(-c2cc(Br)ccc2F)nn1CCO +COC(=O)c1sc(NC(=O)c2ccc(F)cc2F)nc1C1CC1 +CCC(C)NC(=O)c1cc2c(=O)c3ccccc3oc2o1 +COc1cccc(OCC(=O)NCc2cccnc2)c1 +Cc1cnc2n(c1=O)CC(C(=O)Nc1ccccc1C#N)CS2 +Cc1ccc(SCCNC(=O)N2CCC(C(N)=O)CC2)cc1 +Cc1nn(C)c2ncc(NC(C)c3ccc(C#N)cc3)cc12 +CCc1nccc(-c2nccn2C(C)c2nc(C)cs2)n1 +O=C(Nc1nncs1)c1ccc(=O)n(CCOc2ccccc2)n1 +O=C1CCCCN1CCC(=O)N1CCN(c2ccccc2)C(=O)C1 +Cc1cc(C2CCCN2C(=O)C(C)c2c(C)noc2C)no1 +CC(C)(C)CC(O)(Cn1cncn1)c1ccccn1 +COc1ccc(CCC(=O)c2ccccn2)cc1Br +CCn1c(N)nnc1SCc1ccc(Br)cc1 +Cc1cc(C(=O)NC(C)c2ccc(C)c(F)c2)on1 +Cc1ccc(F)c(C(=O)NCC(=O)NC2CC2)c1 +CN(CC(=O)Nc1ccc2c(c1)OCCO2)c1ccccc1 +CC(C)CC(=O)N1CCN(Cc2ccco2)CC1 +Cc1noc(C2CN(CC3CCOC3)Cc3ccnn3C2)n1 +O=C(NCCc1cnn(-c2ccccc2)c1)NC1CCOCC1 +Cc1c(C(=O)Nc2ccc3[nH]c(=O)[nH]c3c2)oc2ccc(F)cc12 +CCC(C)NC(=O)c1ccccc1S(=O)(=O)N(C)c1ccccc1 +C=CCNC(=O)C(C)OC(=O)c1csc2c1CCC(C)C2 +COc1cc(C)c(NC(=O)c2ccc(OC(F)F)cc2)cc1OC +COc1ccc(CNC(=O)NC(C)(C)c2cccc(C)c2)cn1 +CCOCCC(=O)NCC(=O)Nc1ccc(C)cc1Cl +COCC1CN(Cc2ccsc2)Cc2nn(C)cc21 +COc1cc(Cl)c(C)cc1NCc1ccncc1 +COCC(C)NC(=O)NC(c1ccc(Cl)cc1)c1nccn1C +Cc1noc(CCNC(=O)NCc2cc3cc(F)ccc3s2)n1 +CCCOc1ccc(C(=O)N2CCC(C(N)=O)CC2)cc1N +CC(=O)Nc1cccc(C(=O)OCC(=O)NCc2ccccc2F)c1 +COCCCNc1cnn(Cc2ccccc2)c(=O)c1Cl +CCN(CC)C(=O)c1cc(=O)c2cc(N)cc(C)c2o1 +CN(C)c1ccc(C(=O)Nc2ccc(-n3cncn3)nc2)cc1F +COc1cc(CN(C)C(=O)Cc2ccc[nH]2)c(SC)cc1OC +Cn1cc(NC(=O)c2cc[nH]n2)cc(Cl)c1=O +COc1cccc(CC(=O)NCc2c(C)nc3cc(=O)[nH]n3c2C)c1 +CC(=O)N1CCN(c2ccccc2NC(=O)c2cccs2)CC1 +Cc1ccc(NC(=O)C(C)Sc2ncnc3c2cnn3C)cc1C +CC1CN(C2CCN(Cc3c(F)cccc3F)CC2)CCO1 +CN(C)c1nc(N)nc(CSc2nc3ccccc3o2)n1 +NC(=O)CNC(=O)C1CN(C(=O)c2cccs2)C1 +OC(Cn1nnc(-c2cccnc2)n1)c1cc(F)ccc1F +CCn1ncc2c(C(=O)N3CCCCC3C)cc(-c3ccccc3)nc21 +CCN(C)C(=O)CCN1CCc2cc(F)ccc2C1 +CCc1ccccc1NC(=O)COC(=O)c1cc(Cl)c[nH]1 +O=C(NCC1CN2CCCCC2CO1)NC1CCCCC1O +Cc1c(C(N)=O)nnn1Cc1ccc(Cl)cc1 +Cc1ccc(CC(=O)NC(C)C2CCCCC2)cn1 +Cc1ccc(Br)cc1-c1cncc(N)c1 +CCn1c(C)cc(C(=O)Nc2cccc(Cl)c2OC)c1C +CC(C(=O)NCCOc1ccc(F)cc1)n1cncn1 +CN(C)c1cccc(C(=O)NCCc2c[nH]c3ccccc23)c1 +CC(Cc1nc2ccccc2s1)NS(=O)(=O)c1cn(C)cn1 +Cc1nn(C)c(C)c1CC(=O)NC1CC(C)(C)OC1(C)C +CCN(CCO)C(=O)c1ccccc1COc1ccccc1 +C1=CCC(c2nc(-c3cc4ccccc4o3)no2)C1 +Cc1cc(NC(=O)Cn2cc(C3CC3)nn2)n(-c2ccccc2F)n1 +O=C(NCCOc1cccnc1)c1cc(Cl)cc(Cl)c1 +Cc1ccc2[nH]cc(CCNS(C)(=O)=O)c2c1 +COc1ccc2c(=O)c(NC(=O)N3CCCCC3)c[nH]c2c1 +CC1CN(Cc2ccccc2)c2ccccc2NC1=O +COc1ccc(C(=O)NCc2n[nH]c(-c3ccc(OC)cc3)n2)cc1 +O=c1[nH]c(CN2CCc3sccc3C2)nc2ccccc12 +Cc1ccc(CNC(=O)C2COc3ccc(F)cc3C2)c(N(C)C)c1 +COc1cc(OC)c(C(=O)Nc2cccc(F)c2C#N)cc1OC +COc1ncccc1C(=O)NCCc1cc(C)cc(C)c1 +CCn1c(=O)c(=O)[nH]c2cc(C(=O)NCCc3cccs3)ccc21 +O=C(Cn1cnc2ccccc2c1=O)N1CCCC(O)(CO)CC1 +COC(=O)C1=C(C)NC(=O)NC1c1ccc(OC(F)F)cc1 +CCN(C(=O)C1CC=CC1)c1ccccc1S(=O)(=O)CC +CC(C)c1nc2ccc(NCC(=O)NCc3ccco3)cc2s1 +CCOc1ccccc1C(=O)Nc1ccc(NC(C)=O)cc1 +CCS(=O)(=O)N1CCCc2cc(C(=O)NC3CC3)ccc21 +COCC(O)Cn1ccnc1-c1ccccc1C(F)(F)F +O=C(CO)Nc1c(Cl)cc(Cl)cc1Cl +COc1ccc(-c2noc(CNc3cccc(C#N)c3)n2)cc1 +CC(C)N(C(=O)CSc1nc2sccc2c(=O)n1C)C(C)C +CCc1cc2c(=O)n(CCC(=O)Nc3cccc(F)c3)cnc2s1 +COCCC(=O)Nc1ccc(OCC(=O)N(C)C)cc1 +CC(C)(C)NC(=O)c1ccccc1NC(=O)Cc1cccc(F)c1F +COC(=O)c1sc(COc2ccc(F)c(F)c2)nc1C +COC(=O)CNc1ncc(Br)c2cccc(F)c12 +Cc1nn(C)c2sc(C(=O)N3CCN(C(=O)N(C)C)CC3)cc12 +CC(O)CN1CCN(CC(=O)N(C2=CCCCC2)C2CC2)CC1C +COC(=O)C1CCCCCC1NC(=O)C1CCN(C(C)=O)C1 +CCc1nnc(CNc2cc(Br)ccc2NC(C)=O)o1 +CC(=O)N(C)CC(=O)Nc1ccc(F)cc1-c1ccc(Cl)cc1 +COc1ccc(NC(=O)NCCc2cccs2)cc1 +COc1ccccc1CCNC(=O)CS(=O)(=O)c1ccc(C)cc1 +Cc1c(C(=O)N(CC(N)=O)C2CCCC2)sc2ccccc12 +Cc1nn(CC(=O)NC2CCC(C)CC2)c(=O)c(C#N)c1C +CC(C)(CNC(=O)Cc1ccc[nH]1)c1ccncc1 +Cc1cccc(NC(=O)N2CCC3(C2)C(=O)N(C)c2ccccc23)c1 +Cc1ccccc1OCC(=O)N1CCC(OCC2CC2)C2OCCC21 +COc1ccc(C2Nc3ccccc3C(=O)N2C(C)C)c(OC)c1 +Cc1cccc(C(=O)NCC(=O)Nc2cc(-c3ncco3)ccc2C)c1 +OCc1ccccc1-c1cn[nH]c1-c1ccncc1 +COc1nn(C)cc1C(=O)Nc1nnc(SC(C)C)s1 +COc1ncccc1C(=O)Nc1ccc(Oc2ccncc2)cc1 +Cc1ccc(-n2nc(C(=O)OCc3nc(C)no3)c3c2CCC3)cc1 +COC(=O)c1ccc(F)cc1SCc1nnc(C2CC2)n1C +CN(CCc1ccncc1)Cc1cnc2cnccn12 +CCOc1ccc(C(=O)N(C)Cc2ccc(O)cc2)cc1OC +CN(C(=O)NCC1(c2ccccc2)CC1)C1CCC1 +CS(=O)(=O)N1CCC(C(=O)Nc2nccs2)CC1 +CC(C)(C)C(=O)Nc1ccccc1C(=O)N1CCc2sccc2C1 +COC(=O)c1cccc(NC(=O)N(C)CCC(C)C)c1 +Cc1cnn(Cc2ccc(C(F)(F)F)cc2)c1N +CCc1cccc(NC(=O)NCc2ccc(S(N)(=O)=O)cc2)c1 +O=C(Cn1nnc(-c2ccsc2)n1)N1CCCCCC1 +O=C(c1cnccn1)N1CC2CCN(c3ncccn3)CC2C1 +Cc1cccc(C(C(=O)NCc2ccoc2)N(C)C)c1 +Cc1cccc2c1cnn2C(=O)CCC(=O)NC(C)C +CNS(=O)(=O)c1ccc(CCC(=O)Nc2cnccc2C)cc1 +CC(C)(C)C(NCC(=O)NCCC#N)c1ccc(F)cc1 +COc1ccc(NC(=O)Nc2ccc3c(c2)n(C)c(=O)n3C)cc1F +Cc1oc(C)c(C(=O)Nc2ccc(C(N)=O)cc2)c1C +Cc1nc(CN(C)C(=O)Nc2cccc(Br)c2)cs1 +CCn1ncc(CN(C)S(=O)(=O)c2cnn(C)c2C)c1C +OCCOc1ccc(NCc2ccsc2)cn1 +COc1ccc(CC(=O)N2CCc3cc(F)ccc3C2)cc1F +CCCc1cc(NC(=O)c2cnc(Cc3ccccc3)s2)n[nH]1 +COc1c(F)cc(NC(=O)NCc2ccncc2)cc1F +Cc1cc(NC(=O)N2CCC(C)CC2)ccc1C(=O)N(C)C +COC(=O)c1cc(CN(C)C(=O)NCC(C)C)oc1C +CC(=O)NC(CC(=O)NC1(C#N)CCCCC1)c1ccc(C)cc1 +Cc1cc(C(=O)N2CCN(Cc3nc(C)c(C)s3)CC2)on1 +CCOC(=O)C(O)(c1ccc(N)c(C)c1)C(F)(F)F +COc1cc(NC(=O)c2ccccc2-n2cnnn2)cc(OC)c1 +Cc1cc(-c2ccc(=O)n(CCNC(=O)c3cccs3)n2)c(C)o1 +C=CCn1c(SCC(=O)Nc2ccccc2Cl)nnc1C1CC1 +COc1ccc2nc(NC(=O)C3CCOC3)sc2c1 +O=C(NC1CCCc2[nH]c(=O)ccc21)c1cnn(Cc2ccccc2)c1 +O=C(c1ccnc(F)c1)N1CCC(OCc2ccccc2F)CC1 +FC(F)(F)COCCNc1cncc2nnnn12 +CCNC(=O)c1cccc(NC(=O)C2CCOC2)c1 +Cc1cc(CN2CCN(C(=O)c3ccco3)CC2)cs1 +CCc1ccc(S(=O)(=O)NCC(O)Cc2ccccc2)s1 +Cc1ccc(C(=O)N2CCc3ccccc3C2C)cc1 +CC(c1ccccc1)N(C)C(=O)CCCNC(=O)c1ccsc1 +CC(C)CN(C(=O)CSc1nc(N)c(C#N)cc1C#N)C1CC1 +Cc1ccc(C)c(S(=O)(=O)NCCC(=O)NC2CCCC2)c1 +CCN(CC)S(=O)(=O)c1ccc(S(N)(=O)=O)cc1 +Cc1ccc(NC(=O)CN2C(=O)C3=C(CCC3)Nc3ccccc32)cc1 +O=C(CSc1ncnc2[nH]cnc12)Nc1ccc(F)cc1 +Cc1ccc(-c2cc(CO)nn2CCCC#N)cc1C +CCS(=O)(=O)NC(C)c1cc(F)ccc1OC +Cn1cc(CCCNC(=O)NC2(C)Cc3ccccc3C2)cn1 +CN(C)C(=O)c1ccc(-c2ccnc3c2ccn3C)o1 +O=C1C(Cc2ccc(F)cc2)Oc2ccc(O)cc2N1CCO +Cc1sc2c(Cl)cccc2c1S(N)(=O)=O +O=C(NC1CC(=O)N(c2ccccc2)C1)c1cc2c([nH]c1=O)CCC2 +CN1CCN(C(=O)c2noc3c2CC(C(C)(C)C)CC3)CC1 +Cc1ccc2c(ccn2CCC(=O)Nc2nnc(CC(C)C)s2)c1 +CCOCC(=O)NCC#Cc1ccc(C(C)=O)cc1 +Nc1cc(F)ccc1NC(=O)c1ccccc1Cl +CC(C)(C)NC(=O)CCSc1nnnn1-c1ccc(Cl)cc1 +Cc1noc(CN2CCN(C(=O)C(C)CC3CCCC3)CC2)n1 +COCCCNC(=O)c1c[nH]c2c(Cl)cccc2c1=O +Cc1cccc(C)c1NC(=O)CCc1ccc2c(c1)OCO2 +O=c1[nH]n(C2CCOCC2)c2c1C(c1cccc(Cl)c1)CC(O)=N2 +COc1ccccc1C(=O)CN1CCN(CCO)CC1 +O=C(CCCNC(=O)c1cnccn1)Nc1ccc2cc[nH]c2c1 +CCNc1cc(S(=O)(=O)NCC(C)CC)ccn1 +Cc1noc(C)c1NC(=O)CCn1ncc2cc(Cl)ccc21 +Cc1ccn2c(=NC(=O)CCn3cc(C)cn3)[nH]nc2c1 +Cc1ccc(NC(=O)N(C)CCOCC2CC2)cc1C(N)=O +N#Cc1ccc(-c2noc(Cc3cccc(F)c3)n2)nc1 +Cc1ccc2c(c1)NC(=O)C(CC(=O)NCCCOC(C)C)O2 +CN(Cc1nc2ccsc2c(=O)[nH]1)C(=O)c1ccccc1Cl +O=C(COc1ccccc1)NCCc1nnc(-c2ccccc2)o1 +Cc1cc(C(=O)NCC(O)COc2ccc(F)cc2)c2[nH]ncc2c1 +O=C(c1ccc(F)cc1F)N1CC(c2nc(-c3ccccn3)no2)C1 +O=C(Nc1ccc2oc(C3CC3)nc2c1)c1csnn1 +CCc1cccc(OCc2nc(N)nc(C)c2C(N)=O)c1 +CCOc1ccccc1CCC(=O)Nc1nc(C)no1 +CCCOc1cc(C)c(Cl)cc1S(=O)(=O)n1ccnc1CC +Cc1cc(=O)n2nc(NCC3COc4ccccc4C3)sc2n1 +Cc1nnc(COC(=O)Cn2cnc3sccc3c2=O)o1 +O=C(Nc1cc(O)cc(F)c1)c1ccnc(-n2ccnc2)c1 +C=CCNC(=O)c1ccc(NC(=O)c2cc3ccccc3oc2=O)cc1 +CN(C)C(=O)c1ccc(Cl)c(NC(=O)CCc2cccc(F)c2)c1 +COc1cccc(C(=O)N2CCN(C(=O)CC(F)(F)F)CC2)c1 +O=C(NCCC1CCCCO1)NCc1cc(=O)[nH]c2ccccc12 +COc1ccc2c(c1)C=C(c1nc(-c3cnccn3)no1)CO2 +O=C1NC2(Cc3ccccc3C2)Nc2ccccc21 +CCc1onc(C)c1NC(=O)N1CCCCC1C +C=CCNC(=O)Nc1ccc(NC(=O)c2ccsc2)cc1 +Nc1cccc(CC(=O)NCCc2ccc(F)cc2)c1 +CN(C)C(=O)CSc1nnc(Cc2ccc3c(c2)OCO3)o1 +NC(C(=O)NCCc1ccsc1)c1ccccc1 +COc1ccccc1NC(=O)CNc1ccc(-n2cncn2)cc1 +O=C(Nc1ccccc1)c1ccc2c(c1)[nH]c(=O)n2Cc1cccnc1 +COc1ccc2[nH]cc(CCNC(=O)NC(C)c3nccs3)c2c1 +O=C(Cc1cn2ccsc2n1)Nc1ccc2c(c1)OCO2 +CCCN1CCN(S(=O)(=O)c2cccc(C#N)c2)CC1 +O=c1nc2c3c4c(sc3ncn2c2ccccc12)CCC4 +O=C(Nc1nc2c(s1)CCCC2)c1ccc(F)c(F)c1 +Cc1cc2c(cc1C)N(Cc1cccc(C#N)c1)C(=O)CN2 +NS(=O)(=O)c1cnc(N2CCN(Cc3ccncc3)CC2)s1 +O=S(=O)(Nc1cccc(F)c1)c1ccccc1 +CCCn1cc(CNC(=O)OCc2ccccc2)cn1 +CCCC1CN(C(=O)Nc2cccc(NC(=O)CC)c2)CCO1 +COC(=O)c1ccc(=O)n(CC(=O)NC(C)c2ccco2)c1 +CC1(C)CCN(C(=O)C(O)C(O)c2nc3ccccc3s2)C1 +Cc1ccc(-n2ccnc2-c2ccoc2)c2cccnc12 +COc1ccccc1C(NC(=O)CCn1cncn1)c1ccccn1 +COCc1c(C#N)c(NCc2ccccc2)nc(C)c1-n1cccc1 +COc1ccccc1CN(C)C(=O)Cc1ccc(C)s1 +C#CCNS(=O)(=O)c1cccc(C(=O)Nc2ccn(C)n2)c1 +Cc1cnn(CCC(=O)Nc2ccc(-n3cnnn3)c(C)c2)c1 +COc1cccnc1NC(=O)c1ccnc(N(C)C)c1 +c1cncc(-c2n[nH]cc2CNCCc2cccc3cccnc23)c1 +CCc1onc(C)c1NC(=O)c1sccc1Br +O=C(Cn1cnc(C2CCC2)cc1=O)N1CCCC(C(F)(F)F)C1 +O=C1COc2cc(C(=O)NC3CCc4cc(Cl)ccc43)ccc2N1 +Cc1nc(CC(=O)NCCc2noc(-c3ccccc3)n2)cs1 +Cc1cc(C)c(NC(=O)CNC(=O)C2CCCO2)c(C)c1 +CCC(C)NC(=O)c1c[nH]nc1-c1ccc(F)cc1 +CCOc1ccc2c(c1)cc(C1OCCO1)c1nn(C)c(=O)n12 +CC(NC(=O)Nc1cnn(C)c1)c1ccc(Cl)cc1Cl +CC(=O)NC(C(=O)N1CCOC(C)(C)C1)C(C)C +NC(=O)CCN(C(=O)c1cc(-c2ccccc2)no1)c1ccccc1 +Cc1csc(CNC(=O)c2cc(C3CC3)[nH]n2)n1 +O=C(NCc1ccccc1)Nc1nc2c(s1)CCCC2 +O=S(=O)(Cc1ccccc1)N1CCCC1c1nc(C2CC2)no1 +CCOC(=O)c1ccc2nc(NC(=O)c3csnn3)sc2c1 +Cc1cc2c(cc1NC(=O)c1cccs1)n(C)c(=O)c(=O)n2C +Cc1sc(NC(=O)C(C)C)c(C(=O)Nc2ccccc2)c1C +Cc1occc1-c1nnc(SCC(=O)N2CCOCC2)o1 +Cn1ccc(C(=O)N2CCC(c3ccccn3)CC2)n1 +O=C(NCCOc1ccc2c(c1)OCO2)c1ccccn1 +CC(=O)N1CCC(C(=O)OCC2CC=CCC2)CC1 +CC(C)COC(=O)CCc1nc(-c2ccsc2)no1 +O=S(Cc1ncc(-c2cccs2)o1)c1ncccc1Cl +CC(NC(=O)Cc1ccc[nH]1)c1ccc2c(c1)OCCO2 +CC(=O)c1cccc(NC(=O)c2cc(Cl)ccn2)c1 +COC(=O)C1=C(C)NC(=O)NC1c1cc(Cl)cc2c1OCOC2 +Cc1nn(Cc2cccc3cccnc23)c(=O)c(C#N)c1C +COc1ccc2oc(CN3CCOC4(CCC4)C3)cc2c1 +Cc1c(C(=O)OCC(=O)Nc2ccccc2)cnn1-c1ccncc1 +COc1ncccc1C(=O)NCCn1nc(-n2cncn2)ccc1=O +O=C(COc1ccccn1)NCCCC1CCCCC1 +CCn1cc(C(=O)N2CCC(C(N)=O)c3ccccc32)cn1 +CC(C)(C)NC(=O)NCc1nc(-c2ccc(Cl)cc2)no1 +O=C(Cc1ccc[nH]1)NCCCc1cccc(F)c1 +COC1CCN(C(=O)Cc2ccccn2)CC1Cc1ccccc1 +CCc1nnc(-c2ccc(NC(=O)COc3ccccc3F)cc2)o1 +CS(=O)(=O)N1CCC(Cc2ccc(N3CCOCC3)nn2)C1 +CCCc1noc(CCn2cnc3ccccc3c2=O)n1 +CCOC(=O)Cc1ccccc1NC(=O)c1cc[nH]n1 +CC(C)(C)n1cc(NC(=O)c2cc(N3CCNC3=O)ccc2F)cn1 +COc1cccc2c1OCC(NC(=O)Cc1csc(C(C)C)n1)C2 +O=C(NCC1CCCO1)c1c[nH]c2cccc(F)c12 +CC(CC(=O)c1cccs1)NC(=O)Cc1ccc(O)cc1 +O=C(NCc1nc2ccccc2[nH]1)c1ccc(F)cc1Br +N#Cc1ccc(C(=O)Nc2ccccc2C(=O)NCc2ccco2)cc1 +Cc1cc(NC(=O)COC(=O)c2ccc(C)c(C)c2)[nH]n1 +CC1(C)COCCN1C(=O)c1cc2c(s1)CCCC2 +COC(=O)C1CC(Oc2c(F)cc(F)cc2F)CN1 +CN(Cc1nc2c(F)cccc2[nH]1)C(CCO)c1ccccc1 +CC(NC(=O)COc1nncc2ccccc12)c1ccccc1 +CCOC(=O)N1CCN(S(=O)(=O)c2cccc3nonc23)CC1 +COCCNC(=O)N1CCCC(C(=O)N2CCC(C)CC2)C1 +O=C(Nc1cccc(C(F)(F)F)c1)Nc1nccs1 +Cc1n[nH]c2ncc(C(=O)NCCc3nnc4n3CCCCC4)cc12 +COc1ccc(OCC(=O)N(C)Cc2cccc(F)c2)cc1 +COc1cccc(C2NCCc3cc(F)ccc32)c1 +CN(Cc1cccnc1)C(=O)Nc1ccc2c(c1)COC2 +COCCOc1nc(-c2ccccc2)c2c(c1C#N)CCC2 +COc1cc(OC)cc(C(=O)NCC(=O)OC2CCCCC2=O)c1 +CCNC(=O)CN(C)C(=O)c1ccc(F)c(F)c1 +COc1cccc(NC2CCN(c3cncc(C(C)=O)c3)CC2)c1 +CCc1nc2cc(NC(=O)c3cn[nH]c3)ccc2o1 +O=C(Nc1ccc(NCC2CCCO2)c(F)c1)C1CCCO1 +Cc1ccc(-c2noc(CN(C)C(=O)c3ccco3)n2)cc1 +COC(=O)c1c(CC(=O)NCC2(O)CCCC2)[nH]c(C(C)=O)c1C +Cc1ccsc1-c1nccn1Cc1ccc(C(=O)N(C)C)o1 +COc1ccc(N2CCN(C(=O)c3ccsc3)C(C)C2=O)cc1 +COc1ccccc1CC(=O)N1CCNC(=O)C1c1ccccc1 +CC(c1cc(F)ccc1F)N(C)S(=O)(=O)N(C)C +CCCc1nc(C)c(CN2CC(=O)N3CCC(O)CC3C2=O)s1 +O=C(NCc1ccccn1)C1CN(c2nc3ccc(F)cc3s2)C1 +O=c1c2ccsc2ncn1Cc1coc(-c2ccccc2)n1 +CC(=O)N1CCCC1C(=O)NCC1(c2ccc(Cl)cc2)CCCC1 +CCCC(C)NC(=O)COc1ccc2c(c1)OCO2 +Cc1occc1-c1nn(CC(=O)N2C(C)CCCC2C)c(=O)o1 +Cc1cc(C(=O)NCCSc2nccn2C)c2cccc(C)c2n1 +O=C(COc1ccccc1)Nc1nc2c(F)cccc2s1 +Cc1nn(C)c2sc(C(=O)N3CC(C)(C)C3(C)C)cc12 +Cc1nn(C)c(C)c1NC(=O)c1cc2ccc(Cl)cc2n1C +C(=Cc1nn2c(-c3cccnc3)nnc2s1)c1ccccc1 +Cc1ccc(C)c(NC(=O)N2CCC(c3nnc4ccccn34)CC2)c1 +CC(N(C)S(=O)(=O)c1c(N)cccc1Cl)C(C)(C)C +Nc1cnn(CCCCc2ccc3c(c2)OCCCO3)c1 +O=C(CNC(=O)c1ccoc1)NCC1CCCCC1 +Cc1cc(C#N)cc(C)c1OC(=O)c1cc(C(N)=O)cn1C +O=C(Cn1ccc2ncccc2c1=O)N1CCc2ccccc2C1 +O=C(c1nc2ccccc2s1)N1CCc2ncncc2C1 +CCOC(=O)CC(C)NC(=O)c1cn(C)nc1C(C)(C)C +CC(c1ccncc1)N(C)C(=O)c1cc2c(F)cccc2s1 +Cc1cc(-c2nnc(CN3CCN(C)c4cc(F)ccc43)o2)c(C)o1 +N#Cc1cccnc1NCc1cc(Br)cs1 +C=CC1NCCc2cc(OC)c(OCC)c(Cl)c21 +O=C(NCc1ccccn1)NCc1csc(-c2ccccc2)n1 +COc1ccc(O)c2c1C(COc1ccccc1)NCC2 +Cc1ncc(C2Cc3ccc(Br)cc3C2)o1 +CN(C)C(=O)c1ccc(F)c(NC(=O)NCCC2=CCCCC2)c1 +O=C(NCC1CC1)c1sccc1Br +CN(CC(F)(F)F)C(=O)CNc1ccc(Br)cn1 +Cn1cc(C2CCCN2C(=O)c2ccc(NC3CC3)nc2)cn1 +CC(C)C(NCC(N)=O)c1ccc(Cl)cc1F +CC(C)C(=O)Nc1ccc2c(c1)NC(=O)C(C)(C)CO2 +CCNc1nc(C(=O)Nc2c(C)noc2CC)cs1 +Cc1csc(CCCNC(=O)c2cc3ccccc3oc2=O)n1 +N#Cc1ccc(NC(=O)C2CC(=O)N(C3CCCCC3)C2)cc1 +N#CCn1nc(-c2cccnc2)nc1-c1cccnc1 +C#Cc1cccc(NC(=O)NCC(=O)NCc2ccc(OC)cc2)c1 +CCc1nc(CCNC(=O)C2(C)CCCC2)sc1C +O=C(NC1CCN(c2c(F)cccc2F)C1)c1coc2ccccc12 +CCCOC(=O)C(C)(Cc1ccc(O)cc1)NC(C)=O +CCCCNC(=O)N1CC=C(c2ccc(O)cc2)CC1 +COC(CNc1nccc(-c2cccnc2)n1)c1cccs1 +Cc1cc(C)c2c(c1Br)OC(C)C(=O)N2C +CC(O)(c1cnn(-c2ccccc2)c1)C(F)(F)F +Cc1cccc(C)c1NC(=O)CN(C)C(=O)c1ccc(F)cc1 +Cc1ccc(NC(=O)Cn2cc(Br)cn2)cc1N +CC(C)Cc1nnc(NC(=O)N(C)Cc2cccc(Cl)c2)s1 +COC(=O)c1cc(NCc2nsc(N(C)C)n2)c(F)cc1F +COC(=O)COc1cccc(CNC(=O)C2CC=CC2)c1 +C#CCN(CC=C)C(=O)c1cn(CC2CCCO2)nn1 +CCCCN(C(C)CC)S(=O)(=O)c1ccnc(N)c1 +COc1cccc(C(=O)N2CCOCC23CCC3)c1F +O=C(CCn1c(=O)[nH]c(=O)c2ccccc21)NC1CCCCCC1 +Cc1nc(-c2ccc(CC(=O)NC3CCCC3)cc2)cs1 +Cc1ccccc1CS(=O)(=O)NC1CC2CCC1C2 +CC(N)C(=O)c1cn(C)c2cc(Br)ccc12 +CC(C)Cc1ccc(C(C)NC(=O)Cn2ccsc2=O)cc1 +O=C(Nc1ccc(C(F)(F)F)cc1)N(CCO)CC1CC1 +COc1ccc(S(=O)(=O)N(C)C)cc1NC(=O)c1cccs1 +CC1CN(CC(=O)Nc2ccc(Br)cn2)CCO1 +Cc1noc(CNc2ccc(C(=O)OC(C)(C)C)c(C)c2)n1 +Cc1ccccc1C(CC(=O)OC(C)C)NC(N)=O +CC(C)N1CC(C(=O)NCCNC(=O)Cc2ccccc2)CC1=O +O=C(c1csnn1)N1CCCn2cnc(COCCO)c2C1 +CCC(CNC(=O)C(C)NC(N)=O)c1ccccc1 +CC(=O)NC(C)C(=O)N(Cc1ccccc1)c1ccccc1 +Cc1n[nH]c(-c2ccc(F)c(Br)c2)n1 +CC1CCCCC1NC(=O)c1cnn2cccnc12 +Cc1ccc(C(=O)N2CCN(C(=O)c3ccccn3)CC2)cc1 +C=CCN1CCN(S(=O)(=O)c2ccc(CCC)cc2)CC1 +Cc1n[nH]cc1CNC(=O)c1ccc2[nH]cnc2c1 +COc1cccc(C(=O)Nc2cnc(-c3ccccc3)nc2)c1 +CC(CCO)NC(=O)c1cc(-c2ccccc2)no1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)OCC1CCCCC1 +Cn1cnc2c(NCc3ccccc3)nc(NCCO)nc21 +COCc1ccc(C(=O)OCC(=O)Nc2c(F)cccc2F)cc1 +CCc1cnc(CCNC(=O)Nc2cccc(S(C)=O)c2)s1 +CC(=O)N1CCC(C(=O)N2CCc3cc(F)ccc3C2)CC1 +CCCOC(=O)C(CC)n1c(=O)oc2ccc(CO)cc21 +CC1(C)CC2CC(C)(CN2C2=NC(Cl)=NC3=NC=NC32)C1 +COC(=O)Cc1cn2nc(-c3cccs3)c(C)c2[nH]1 +CC1CN(C(=O)c2nc(N)ccc2Cl)C(C)CO1 +O=C(c1c[nH]nn1)N1CCN(C(=O)C2CCCCC2)CC1 +Cc1cc(C(=O)Nc2ccc3ccccc3c2)n(C)n1 +CC(=O)NC(C)C(=O)Oc1cccc(C(=O)NCc2ccccc2)c1 +COc1cccc(C(=O)Nc2ccc(O)c(Cl)c2)c1F +CC(=O)c1cccc(OCc2cc(C(=O)N3CCCC(O)C3)n[nH]2)c1 +Cc1cc(NC(=O)c2cccc(OCc3ccccc3C#N)c2)no1 +CCOC(=O)CN(CC)C(=O)c1cc(F)c(F)c(F)c1F +CCC1(CO)CCCN(S(=O)(=O)c2ccc(OC)cc2)C1 +COCC(O)CN(C)C(=O)CCc1cc(Cl)cs1 +Cc1cccc(C(=O)N2CCC(CN3CCOCC3)CC2)c1C +COc1ccc(CCNC(=O)C(N)c2ccccc2)cc1F +COCCCC1CCCCN1C(=O)c1cnc2c(O)cccn2c1=O +O=C(CCCNC(=O)c1ccco1)Nc1ccc(Cl)cn1 +C=CCNC(=O)N(CC)Cc1cnc2ccccn12 +CCNC(=O)N(Cc1cccnc1)Cc1ccco1 +CCOc1ccccc1C1C2(C#N)C(N)=NC(OC)(OC)C12C#N +CC(Oc1ccc(Cl)c(Cl)c1)C(=O)N1CCC(C(N)=O)C1 +Cc1ccc(Cl)cc1-n1ccc2c(cnc3ncnn32)c1=O +Cc1cc(=O)c(C(=O)NC2CCN(c3ccc(Cl)c(F)c3)C2)c[nH]1 +CC(C)(Oc1ccc(Cl)cc1)C(=O)NCC1(CO)CC1 +CC(C)Sc1ccc(S(=O)(=O)N2CCCCC2)cn1 +O=C(NC(c1ccccc1)c1ccccn1)NC(C1CC1)C1CC1 +CCNC(=O)c1ccc(C)c(NC(=O)Cc2cccc3cccnc23)c1 +CCn1nc(-c2ccc(C)c(Cl)c2)cc(CC#N)c1=O +Cc1ccc(NC(=O)c2nnc(C)n2C2CC2)cc1C +O=C(NCCCn1ncc2ccccc21)C1CCC1 +COc1cc(C(=O)Nc2ccc(C)cc2)c(-n2cnnn2)cc1OC +Cc1ccnc(NC(=O)C(C)Cn2nc(C)c(C)c2C)c1 +CC(=O)c1ccc(NC(=O)c2ccc(S(=O)C(C)C)cc2)cc1C +c1ccc2c(c1)CCN2Cc1nnc(C2CCCO2)o1 +O=C(CNc1ccc(Cl)c(F)c1)NCc1ccc2c(c1)OCO2 +CN1CC(C(=O)N2CCCC(n3cncn3)C2)CC1=O +O=C(Cn1c(-c2ccccn2)noc1=O)N1CCOCC1 +CC(O)CNC(=O)c1nc(CC(=O)N2CCOCC2)no1 +O=C(c1cc2ccccc2oc1=O)N1CCc2cc(F)ccc2C1 +CNc1ncc(C(=O)NC(C)c2cccs2)cc1Cl +CCC1CCC(=O)C(C2(O)C(=O)Nc3ccccc32)C1 +COC(=O)CCCSc1nnc(-c2ccco2)n1N +COc1ccc(C(=O)Nc2ccc(CN3CCCC3=O)cc2)c(O)c1 +CC(C1CC1)N(C)C(=O)c1ccc(-n2ccnn2)cc1 +CC(=O)Nc1ccc(NC(=O)CNc2ccc(C)c(Cl)c2)cc1 +O=c1c(C(F)(F)F)cccn1Cc1ccn(-c2ccccc2)n1 +Cc1cccc(NC(=O)NCC(O)c2ccsc2)c1 +c1ccc(Cn2ncc3[nH]c(-c4ccsc4)nc32)cc1 +CC(C)NC(=O)C1CCN(Cc2cnc(C3CCCC3)s2)CC1 +Cc1ccnc2nc(C(=O)NCc3ccccc3OC3CCC3)nn12 +COc1ccc(C(=O)NCc2cc(N)ccc2OC)cc1 +COc1cccc(C(=O)Nc2nnc(-c3sc(C)nc3C)o2)c1 +Cn1c(=O)cc(OCC(=O)NCc2cccnc2)c2ccccc21 +CCc1ccc(CNC(=O)Cc2nnc(-c3cccs3)o2)cc1 +C=CCNc1nc(C2CCCCC2)nc(OCCC)c1N +CCOC(=O)c1ccc(NCCNC(=O)NC)c(N)c1 +COCCOc1cccc(NC(=O)N(C)Cc2ccoc2C)c1 +Cc1ccc(-n2cnnc2SCC(=O)OCC2CC2)cc1C +O=C(CSc1ncnc2sccc12)c1cccs1 +Cc1ccccc1N(CC(=O)Nc1nccs1)S(C)(=O)=O +CC1CCCC(CNC(=O)NCc2ccc(-n3cncn3)cc2)C1 +CCc1onc(C)c1NC(=O)NC(c1ccc(OC)cc1)C1CC1 +COc1ccc(-c2cnc(CNCc3cccnc3)s2)cc1 +CCN(CC)c1ccc(S(=O)(=O)N2CCC(C)CC2)cc1N +CC(C)(O)C1NCCc2ccc(F)c(C(F)(F)F)c21 +COc1ccnc(NC(=O)c2cc(C)n(-c3nccs3)c2C)c1 +CC(C)Cc1cc(C(F)(F)F)c(C#N)c(SCC(N)=O)n1 +CCN(C)C(=O)c1csc(-c2cc(Br)cs2)n1 +CCC1COCCN1S(=O)(=O)c1c(C)nn(-c2ccccc2)c1C +CCOC(=O)C1CCN(c2ncnc(OC3CCCCC3)c2N)CC1 +O=C(CN1CCOc2ccccc21)Nc1nccs1 +Cc1nn(C)c(C)c1CN(C)S(=O)(=O)c1ccc(C(C)C)cc1 +Cc1ncc(CN2CCN(c3cc(C#N)ccn3)CC2)s1 +Cc1c(C(=O)NCCCC(N)=O)oc2ccc(Cl)cc12 +COc1cc(F)ccc1NCc1c(C)nn(C)c1C +Cn1nc(C(=O)NC2CCc3ccccc32)c2ccccc21 +COCCCn1ccc(NC(=O)NCc2ccc(F)c(Cl)c2)n1 +O=C1NC(c2cc(F)c(F)c(F)c2)Nc2ccccc21 +O=C(CCc1ccccc1F)Nc1nccs1 +CCC(O)CN1CCN(C(=O)c2cn(C)nc2-c2cccnc2)CC1 +CCn1cc(C(=O)NCC(C)Cn2cccn2)c(C(C)C)n1 +O=C(c1ccccc1)c1c2ccccc2c2[nH]c(=O)[nH]c(=O)n12 +Cn1c(=O)[nH]c2cc(C(=O)N3CCCCC3Cn3cccn3)ccc21 +CC(C)Cc1nnc(NC(=O)c2cnn(-c3ccccc3)n2)s1 +CC1CCCC(NC(=O)C(N)c2ccccc2)C1C +CCOC(=O)N1CCN(CCOc2ccc(F)cc2)CC1 +Cc1nc2cc(C(=O)NCCc3ccccc3)ccc2[nH]1 +Cc1cnc(NC(=O)CN(CC(C)C)C(=O)c2ccccc2F)s1 +CC(=O)c1c[nH]c(C(=O)Nc2nc3c(s2)CCCC3)c1 +C=CCOC(=O)C1CCC(=O)N(c2ccc(C)c(C)c2)C1 +CCOC(=O)c1cn[nH]c1-c1cccc(OC)c1OC +O=C(NCc1ccc(S(=O)(=O)NC2CC2)cc1)N1CCCC1 +O=C(NCc1cc2c(s1)CCC2)C1(c2ccccc2)CCOCC1 +CC(NC(=O)N(C)CC1CCCO1)c1nc2ccccc2[nH]1 +CN1CC(C(=O)Nc2ccc(Oc3ccccc3C#N)cc2)CC1=O +CCN(CC)C(=O)Cc1ccc(NCc2c(C)nn(C)c2C)cc1 +CN(Cc1ccc(F)cc1Cl)C(=O)C1CCC(=O)N1 +CC(C)(C)CCC(=O)Nc1ccc(Br)cn1 +Cc1ccc(NC(=O)Cc2noc(-c3cc(C(N)=O)cs3)n2)cc1 +CCN(CC(=O)NC(C)(C)C)C(=O)C(C)NC(=O)c1ccccc1 +COc1ccc(C)cc1NCC(=O)N1CCCC1c1cccs1 +COC(=O)c1n[nH]c2ccc(NC(=O)c3cnc(C)cn3)cc12 +CCC(=O)CSc1nnc(N2CCOCC2)n1-c1ccccc1C +COC(=O)C(C)(C)CNC(=O)c1ccncc1F +O=C(c1cnc(-c2ccccc2)s1)N1CCOC2CCCC21 +Cc1cc(C(=O)NCCn2nc(-c3ccccc3)ccc2=O)nc(C)n1 +Cc1nc(C2CCCN(C(=O)CN3CCCNC3=O)C2)sc1C +CNc1cccc2ccnc(OCc3cccnc3)c12 +Fc1cc(F)c2c(c1)C(c1cc(Cl)ccn1)NCC2 +CCNC(=O)CNC(=O)CCn1ncc2ccc(C)cc21 +CN(Cc1ccc2c(c1)OCO2)C(=O)c1ccc(O)c(Cl)c1 +Cc1ccc(-c2noc(CS(=O)(=O)c3ccc(C)cc3)n2)cc1 +O=C(NCc1ccc(CN2CCOCC2)cc1)c1ccc(F)cc1F +O=c1oc(-c2ccco2)nn1CCOc1ccc2ccccc2c1 +COCCN(C(=O)c1cncc(Br)c1)C(C)COC +Cc1cccc(OCC(C)NC(=O)N2CCC(CC(N)=O)CC2)c1 +CC(=O)c1ccc(NC(=O)COC(=O)c2cc(C)ccc2C)cc1 +CC(Oc1ccc(Cl)cc1)C(=O)Nc1ccc2c(c1)OCC(=O)N2 +CCN(Cc1noc(CC(C)C)n1)C(=O)c1cn2ccsc2n1 +COCCOc1ccc(NC(C)c2cccs2)cn1 +Cc1c(C(=O)NC2C3CC4CC(C3)CC2C4)cnn1-c1ccccn1 +Cc1c(Br)cc(Cl)c2c1NC(=O)CCO2 +O=C(Nc1ccc(CN2CCOCC2)cc1)c1ccc(F)cc1F +Cc1occc1COC(=O)c1ccc2c(c1)NC(=O)CS2 +CN(CCOCC1CC1)C(=O)c1scnc1C1CC1 +O=C(CNC(=O)c1ccccc1)OCc1coc(-c2ccccc2)n1 +Cc1ccc(C)c(C(=O)Nc2cccc(C(=O)N3CCOCC3)c2)c1 +Nc1c(-c2cccnc2)nc2c(C(F)(F)F)cccn12 +Cc1ccc(NC(=O)CCSc2ccccn2)cc1C(=O)N(C)C +CC(OCC(F)(F)F)c1nc(CC(=O)NC2CCCCC2)no1 +COc1nc(C)cc(C)c1CNC(=O)N1CCC(N(C)C(C)=O)CC1 +Cc1c(NC(=O)C2CCOC2)cccc1C(=O)NC1CCCCC1 +CC(C)(NC(=O)c1ccc2nncn2c1)c1cccc(F)c1 +Cc1ccc2c(Nc3cccc(F)c3)c(-c3nc(C)no3)cnc2n1 +CCCc1nc(CN2CCc3c(N)cccc3C2)cs1 +Cc1nc(NC(=O)C2(c3ccccc3)CCOCC2)sc1C +Cc1cc(NC(=O)c2ccc(S(=O)(=O)N(C)C3CC3)cc2)no1 +C=CCn1cnnc1SC(C)C(=O)Nc1ccc(C#N)c(Cl)c1 +Cc1cccc(-n2nc(CC(C)C)nc2CCc2nncn2C)c1C +O=C(Cn1cnc2ccccc2c1=O)NCCc1ccc(Cl)cc1 +CCC(NS(=O)(=O)c1ccc(C#N)cc1F)C(=O)OC +CCn1c(=NC(=O)Cn2cccn2)[nH]c2cc(Br)ccc21 +COc1cc(-c2ncc(C)s2)cc(N)c1OC +O=C(c1ccnc(OC2CCOC2)c1)N1CCc2cc(F)ccc2C1 +Cc1nc(C(=O)N2CCCC(c3cccc(-n4ccnc4)n3)C2)co1 +Cc1nnc(-c2cccc(C(=O)OC3CCCC3n3cccn3)c2)o1 +Cc1cccc(NCc2ccccc2F)c1C(=O)N1CCCC1 +N#CCc1nc2cccnc2n1Cc1ccc(N)nc1 +c1ccc2c(c1)CC(c1ccc3c(c1)OCCCO3)N2 +O=C1CCc2cc(-c3csc(C4CC4)n3)ccc2N1 +Cc1ccc(-c2nc(C(=O)N(C)CC(O)C3CC3)cs2)cc1 +COC1C2=C(CCCC2)C(=O)N1Cc1ccc2c(c1)OCO2 +CC1Cc2cc(C(=O)NC3CCCCC3)ccc2N1S(C)(=O)=O +O=C(CSc1nnc(-c2cccnc2)o1)Nc1ccccc1F +Cc1nncn1CCNC(=O)c1ccnc(OC2CCC2)c1 +Cc1ccc(N2CCC3C2CC(=O)N3Cc2cccc(C)n2)nn1 +COCC(O)CNC(=O)Nc1nn(-c2ccccc2Cl)cc1C +CN(C)c1ccc(NC(=O)Cc2ccc(Cl)cc2)nc1 +CC(C)(C)c1ccc(NC(=O)N2CC3CC2C(=O)O3)cc1 +Cc1cc(CN(C)C(=O)c2cc(-c3ccccc3)no2)no1 +O=C(CCC(=O)N1CCc2sccc2C1)OCc1ccccc1 +CC(CNC(=O)c1ccc(-n2ccnn2)cc1)CN1CCOCC1 +O=C(Cc1c(F)cccc1F)OCCNc1cccnn1 +CCC1CCCCN1C(=O)NCCS(=O)(=O)NCC1CCC1 +Cc1nc2c(C(N)=O)cnn2c(C)c1CCC(=O)Nc1nccs1 +COc1ccc(NC(=O)CCNc2ncnc3[nH]cnc23)cc1 +COc1ccc(CC(=O)Nc2ccc(F)c(F)c2)c(OC)c1 +COCc1ccc(C2CCCN2C(=O)NCC(C)(C)OC)o1 +Cc1cccc(N2CC(C(=O)NC(C3CC3)C3CC3)CC2=O)c1C +Cc1cc(C(=O)CSc2ncccn2)c(C)n1Cc1ccccc1 +CCC(CNC(=O)NCC1CCOC1)c1ccccc1 +O=C(Nc1ccc(F)cc1)N1CCC(Oc2ncccn2)CC1 +CCNC(=O)C1CC(=O)N(c2ccc(F)cc2)C(C)=C1C(=O)OC +Cc1ccc(NC(=O)c2cnn(C(=O)c3ccccc3)c2N)cc1 +O=C(NC1CCCCC1C(F)(F)F)c1ccsc1 +Cc1csc(-c2ccc(NC(=O)NCC(=O)N(C)C)cc2)n1 +CCCC(NC(N)=O)C(=O)NC(C)C(=O)NC(C)(C)C +CCOC(=O)N1CCC(NC(=O)c2nc(-c3cccnc3)no2)CC1 +NC(=O)NC(CC(=O)NC1CCCC1)c1cccs1 +CCCCN(C)C(=O)c1cccc(Oc2ccccn2)c1 +CC(=O)Nc1ccc(NC(=O)CCc2c(C)nn(C)c2C)cc1Cl +CCCOC(=O)C1=C(C)N(CC)C(=O)NC1c1ccc(O)c(OC)c1 +Cc1nc(CCNC(=O)c2cc(C)n(-c3ccccc3)n2)cs1 +COc1ccc(OC)c(CC(=O)Nc2ccccc2)c1 +Cc1ccnc(-n2c(C)c(C)c3c(NCc4ccco4)ncnc32)c1 +CC(=O)c1ccccc1NCc1nc(-c2ccco2)no1 +O=C(OCCn1cncn1)c1cc2ccccc2cc1OC(F)F +Cc1ccccc1C(C)NC(=O)c1n[nH]c(=O)c2ccccc12 +CC(NC(=O)c1cc(Cl)c2c(c1)OCCO2)c1ccccn1 +N#Cc1cc(-c2ccc(Cl)cc2)n(-c2ncccn2)n1 +COc1ccc(C(=O)Nc2cc(OC)c(OC)cc2C)cc1 +COC(=O)c1cc(C2Nc3ccc(Cl)cc3C(=O)N2C)oc1C +CC(C)(C#N)NC(=O)CCc1ccccc1Cl +CC(Cc1ccsc1)NC(=O)c1cccc2c1OC(C)C(=O)N2 +c1cc(CN2CCC3(C2)OCCO3)c2c(c1)OCCCO2 +c1nc(N2CCOCC2)ncc1CNc1ccc2c(c1)COC2 +CCC(=O)Nc1cccc(NC(=O)C(C)Oc2ccccc2)c1 +Cn1cc(NCC2(c3ccc(F)cc3)CCOC2)cn1 +C=CCNC(=O)CSc1ccc(-c2cccs2)nn1 +CC1=C(C(N)=O)C(c2ccc(Cl)cc2)n2nnnc2N1 +O=C(CN1CCCCCC1=O)Nc1nccs1 +CN(Cc1nc2ccccc2s1)C(=O)c1ccncc1 +COc1ccccc1C(=O)NCc1cccc(C(N)=O)c1 +Cc1cc(NC(=O)NC(C)(C)c2nccs2)ccc1C(=O)N(C)C +Cn1cnc(CNC(=O)C2Cc3cccc(F)c3O2)n1 +CNC(=O)C(C)Oc1ccccc1Br +CCc1nnc(SCC(=O)Nc2nc(C)cs2)n1CC(C)C +CC(=O)OCC1OC(Sc2ccccc2)C=CC1OC(C)=O +CC1CCCN(C(=O)Nc2ccc3c(c2)NC(=O)CO3)C1 +CCn1cc(CNCC(c2ccc(Cl)cc2)n2cccn2)cn1 +COc1ccc2c(CC(=O)NC3CCc4nnc(C)n4C3)coc2c1 +CCn1ccnc1CNc1nncc(-c2cccc(OC)c2)n1 +CC(=O)N(Cc1cc(=O)[nH]c2ccccc12)c1cccc(C)c1 +Cc1ccc(S(=O)(=O)Nc2nnc(CC(C)C)s2)o1 +C=C(C)CSc1nnc(-c2ccncc2)n1CC +CC(C)(CO)NC(=O)CCOc1ccc(Cl)c(Cl)c1 +Cc1c(C(=O)NCc2nc3ccccc3[nH]2)nnn1Cc1ccccc1 +CC(NC(=O)CN1CCOC(Cn2cncn2)C1)c1cccs1 +Cc1ncc(COc2ccc(C#N)cc2Cl)s1 +Cc1nc(-c2cccs2)c(CCC(=O)N(C)c2ccccc2)s1 +CCOC(C)C(=O)Nc1cc(F)ccc1C(C)=O +CC1CCc2nc(CN(C)C(C)CC#N)sc2C1 +CCN(C(=O)c1ccc(N)cc1Cl)c1ccccc1 +CCN(Cc1ccccc1Cl)c1cccc(N)c1 +CCOC(=O)C1OCCN1C(=O)OCc1ccccc1 +CCc1sc(=O)n(Cc2nnc(C)o2)c1-c1ccccc1 +Cc1ccccc1CN(C)S(=O)(=O)c1ccccc1F +CN(Cc1cscn1)C(=O)C(N)c1ccccc1 +O=C(NCC(O)(c1ccccc1)C(F)(F)F)c1c(F)cccc1F +COc1ccc2c(c1)CCN(C(=O)c1sc(C(C)C)nc1C)CC2 +CCN(CCO)C(=O)C1CCN(C(=O)c2ccc(F)cc2)CC1 +CCC(C)C(NC(N)=O)C(=O)Nc1ccc2c(c1)oc(=O)n2C +CCCN(CCO)C(=O)NCC1(C)Cc2ccccc2C1 +CCc1ccc(O)c(C(=O)Nc2ccc(CN3CCOCC3)cn2)c1 +Cc1nc(N2CCCC(CCC(N)=O)C2)nc(C)c1CC(C)C +O=C(NC(c1ccc2c(c1)OCCO2)C1CC1)C1CC1 +COc1ccc(C(=O)c2ccc(C)nc2)cc1OC +CN(Cc1ccc(F)cc1)C(=O)c1cccc(C(F)(F)F)c1 +O=C(NCCOc1ccccc1)c1n[nH]c2ccccc12 +CCc1onc(C)c1NC(=O)NCCCc1nc2ccccc2[nH]1 +O=S(=O)(NCC(O)(c1ccccc1)C1CC1)C1CCCCC1 +Cc1cnn(CC2CCCN2C(=O)CCCc2nc(C(C)C)no2)c1 +Cc1occc1-c1nnc(SC(C)c2nnc(CC(C)C)o2)n1N +CC1CCC2C(CCCN2C(=O)c2ccc(-n3ccnc3)nc2)C1 +Cc1nc(C(=O)N(C)C)ccc1C(=O)N(C)c1ccc(Cl)cn1 +O=C(NCCc1ccccc1)C1CC(=O)N(c2ccc(Cl)cc2)C1 +O=C(Cc1cccc(O)c1)NCC1(CN2CCOCC2)CCCCC1 +Cc1nnc(SCc2nccn2Cc2ccccc2)s1 +CCOc1ccc(NC(=O)c2ccc3c(c2)OCCCO3)cc1 +CN(C)c1nc(Nc2ccccc2)c2cnn(C)c2n1 +COC(=O)C1(CC#N)CCN(C(=O)OC(C)(C)C)CC1 +O=C(C1CCCC1)N1CCC(Oc2cnccn2)CC1 +COc1cccc(-c2nc(C(=O)OCc3nc(C)c(C)o3)c(C)[nH]2)c1 +CCCS(=O)(=O)N1CC=C(c2cccc(OC)c2)CC1 +Cc1cc(C)n2ncc(-c3noc(=O)n3CC(=O)NC3CC3)c2n1 +C#CCNC(=O)NC(C)C(=O)NCc1ccccc1 +COc1cc(Cl)ccc1C(=O)N1CCN(CCO)CC1 +CC(CO)CN(Cc1ccccc1)Cc1cnc[nH]1 +CCOc1ccc(NS(=O)(=O)c2cc(NC(C)=O)ccc2C)cc1 +CCC(C)NC(=O)CNc1ccc(C(=O)NC)cc1 +CCC(=O)N1CCC(NC(=O)c2cccnc2OCC(F)F)C1 +COc1ccc(C(C)(C)C)cc1S(=O)(=O)n1cccn1 +CCCn1nnnc1CSc1nnc(NC(C)(C)C)s1 +Cc1cc(C)n2c(CNC(=O)c3ccccc3C)nnc2n1 +COc1cccc(NC(=O)Cc2cn3ccsc3n2)c1 +N#CCCN(Cc1cccnc1)S(=O)(=O)c1cccnc1 +CCS(=O)(=O)NCCN(C)c1ccccc1N(C)C +O=C1NCCCCC1Sc1nc(C2CC2)n(-c2ccccc2)n1 +CN1CCN(C(=O)c2ccc(OCC(F)(F)C(F)F)nc2)CC1 +COc1ccc(C(=O)C2CCCN(c3cnccn3)C2)c(C)c1 +CC(=O)N(C)Cc1nc2ccccc2n1CC(=O)N1CCCCCC1 +O=C(Cn1nc2ccccn2c1=O)Nc1ccccn1 +Cc1nc(CSc2nnnn2C(C)C)oc1C +CCn1c(=O)n(CC(=O)NC(C)c2ccccc2)c2ccccc21 +CCCC(C)(C)NS(=O)(=O)c1ccccc1F +CCOCC(=O)NCc1ccc(S(=O)(=O)N2CCCCC2)cc1 +CCn1cnnc1CNC(=O)NCC(O)c1ccc(Cl)cc1 +CCc1cc(C(=O)N2CCN(C(=O)c3ccccc3O)CC2)[nH]n1 +CS(=O)(=O)N1CCCC(NC(=O)C2CCOC2)C1 +O=C(NCc1ccsc1)NCC(O)c1ccc2ccccc2c1 +Cc1nc(C2CCN(C(=O)c3cc(C(C)C)[nH]n3)CC2)no1 +O=C(Nc1cccc2ncccc12)c1ccc(F)c(F)c1 +N#Cc1cccc(-n2ccnc2C(=O)NC2CC2)c1 +O=C(Cn1cnc2ccccc21)NCc1cnc2ccccc2c1 +OCC1CCCN(c2nnnn2-c2ccccc2)C1 +Cc1ccc(C(=O)N2CCC3(CC2)CC(OCC(C)C)C3)cn1 +CCNc1nc2c(c(=O)n(C)c(=O)n2CC)n1C +Cc1ccc(NC(=O)C2CCc3cn[nH]c3C2)cc1S(C)(=O)=O +c1ccc2oc(-c3nnc4sc(CN5CCOCC5)nn34)cc2c1 +CCOc1ccc(OCc2nc3ncccc3o2)cc1 +Cc1cc(OCC(=O)Nc2cccc(Cl)c2)nc2c1c(C)nn2C +CNC(=O)CCCC(=O)c1cc(F)ccc1OC +CCCOC(=O)c1ccc(OC(F)F)c(OC)c1 +CCN1C(=O)CCCC12CCCN(C(=O)c1ccco1)C2 +NC(=O)C1CCN(C(=O)c2cc(-c3cccc(Cl)c3)[nH]n2)CC1 +Cc1nc(C(=O)NC2CCCc3occc32)c2ccccn12 +CC(C)CCN1C(=O)C(C)(C)COc2ccc(N)cc21 +NC(=O)c1ccc(=O)n(-c2nc3ccccc3[nH]2)c1 +Cc1ccc(C(=O)NCc2nnnn2-c2ccc(F)c(F)c2)cc1C +NS(=O)(=O)c1ccc(-c2csc(-c3ccoc3)n2)cc1 +COc1ccc2[nH]cc(CNc3ncccn3)c2c1 +Cc1[nH]c(=O)[nH]c(=O)c1CCC(=O)N1CCCC1 +NC(=O)CCN(Cc1ccccc1)C(=O)Nc1ccc(Cl)cc1 +CCc1cc2c(NCCc3ccc(O)cc3)ncnc2s1 +O=C(Cc1n[nH]c2cc(Cl)ccc12)NCc1cccc(F)c1 +CCC(C(=O)Nc1c(C)nc2scc(C)n2c1=O)c1ccccc1 +O=C1C2CCC(CN(c3ncccn3)C2)N1CC1CCC1 +Cn1cnnc1SCc1nc(-c2ccc(Cl)cc2)no1 +CC(=O)N1CCN(CC(=O)N2CCCCC2)CC1 +O=C(Nc1cc(F)ccc1Cl)c1ccnc(-n2cncn2)c1 +CCOc1cc2c(cc1O)C(C1CCCO1)NCC2 +Cc1cc(C)n(CC(=O)Nc2cccc(Cl)c2C)c(=O)c1C#N +CCc1nc(C(=O)NCCNC(=O)C(C)(C)C)co1 +CC1CCC(N(C(=O)c2csc(S(N)(=O)=O)c2)C2CC2)CC1 +CC(C)CCn1cc(C(=O)N2CCOCC2C2CC2)nn1 +Cc1oc(C)c(C(=O)Nc2nc(CC(N)=O)cs2)c1C +CNC(=O)C1(NC(=O)c2cn3cc(C)ccc3n2)CCCCC1 +COc1cc(C)c(C)cc1-c1cnn(C)c(=O)c1N +O=C(NC1CCC(n2cnnc2)CC1)c1cn2ccsc2n1 +CC(NC(=O)Nc1ccccc1)C(=O)N1CCC(CC(N)=O)CC1 +CC1CCC(N(C(=O)Cn2cc(Br)cn2)C2CC2)CC1 +Cc1[nH]c(=O)c(C#N)c(C)c1CCC(=O)Nc1cccnc1N(C)C +N#CCOc1cccc(CC(=O)N2CCOc3cccc(F)c32)c1 +CCOC(=O)CC1CCCCN1C(=O)c1cccc(-c2ncc[nH]2)c1 +CCOc1ncccc1CNC(=O)c1ccc(C#N)cc1 +CCn1cc(C(=O)c2nc(-c3ccc(C#N)cn3)no2)cn1 +O=S(=O)(c1ccc(Cl)cc1)N1CCCCC1C1OCCO1 +CC(CO)C(C)NC(=O)NCc1ccc(Oc2cccc(F)c2)nc1 +COc1c(NC(=O)N(C)CCOc2ccccc2)c(C)nn1C +NC(=O)CCN(CCN1CCCC1=O)c1ccc(F)cc1 +Cc1cc(C(=O)N2CCC3(CC2)OCCO3)n[nH]1 +CN(C(=O)CCn1ccccc1=O)c1ccccc1 +O=C(Nc1cc(Cl)ccc1-n1cncn1)C1CC1 +COc1cn(-c2ccc(F)cc2)nc1C(=O)NCCN1CCOCC1 +COc1ccc(Cn2ccnc2-c2coc(C(C)C)n2)cc1 +Cc1c(C(=O)N(CCc2ccccc2)C2CCCC2)cnn1C +Cc1cc(NC(=O)c2cccs2)c(=O)n(Cc2cccc(F)c2)c1 +N#CC(CC(=O)Nc1ccc2c(c1)OCCO2)c1ccccc1 +O=C1CCC2(CCCO2)CCN1CCCOCc1ccccc1 +CC(=O)c1csc(NC(=O)c2ccc(-n3ccnn3)cc2)n1 +C=CC1CCN(C(=O)c2cnc(C3CCCO3)s2)CC1 +Cc1ccc(-c2ncco2)cc1NC(=O)c1ccc(-n2cnnc2)cc1 +O=C(NC(c1ccccc1)c1ccco1)N1CCC2(CC1)OCCO2 +COCCNC(=O)CSc1nnc(-c2ccc(C)cc2)n1N +CN(CC1CC1)C(=O)c1cc(=O)[nH]c2ccc(Br)cc12 +CC(C)(C)OC(=O)CNC(=O)Cc1ccc(F)cc1F +Cc1oc2ncnc(N3CCCCC3)c2c1C(=O)NC1CCCC1 +Cc1cccc(S(=O)(=O)Nc2cccc(-c3ccnc(C)n3)c2)c1 +O=C(c1ccccc1)c1nc[nH]c1C(=O)Nc1ccccn1 +Cc1cc(NCC(=O)N(C)C)ccc1C(=O)N(C)C +COc1ccc(CC(=O)NC2CCCCC2)cc1F +N#Cc1ccc(-c2noc(C3CC3c3ccc(Cl)cc3)n2)nc1 +CNc1nc(NCc2ccccc2Cl)c2cnn(C)c2n1 +Cc1csc(C(C#N)C(=O)CC2CCCCC2)n1 +CCOC(=O)CN(C(=O)Cc1ccncc1)C(C)C +CNC(=O)c1cccc(-c2cc(O)cc(C#N)c2)c1 +CNS(=O)(=O)c1ccc(C(=O)N(C)CCC(C)C)o1 +CCc1nnc2nc(-c3ccc(OC)cc3OC)[nH]n12 +CCc1cc(=O)n(CCNC(=O)Nc2ccc(OC)cc2OC)cn1 +NC(=O)C1CCCN(C(=O)c2ccc(F)c(N)c2)C1 +CNC(=O)Cc1ccc(NC(=O)N(C)Cc2ccccc2C)cc1 +CCCCOc1ccc(C(=O)Nc2nc(C)no2)cc1OC +CCCCCNC(=O)N1CCN(C(=O)c2ccc(OC)cc2)CC1 +CCOCCCn1c(=NC(=O)Cc2ccc[nH]2)[nH]c2ccccc21 +Cc1ccc(CN2CCC3C2CCN3C(=O)c2cscn2)s1 +O=C(c1cccnc1)N1CC(c2nc3ccccc3[nH]2)C1 +CN(C(=O)CNC(=O)c1c[nH]c2ccccc2c1=O)C1CC1 +Cc1ccc(Cl)cc1NC(=O)c1ccccc1SCC(N)=O +CC1CCCC(OC(=O)c2cnc3ccccn3c2=O)C1 +Cc1ccc(S(=O)(=O)N2C(C)CCCC2CO)c(F)c1 +CC(C)COCCNC(=O)c1ccc(-n2ccnn2)cc1 +CCn1cc(C(=O)NCc2ccc3c(c2)OCO3)c2n[nH]c(=O)c-2c1 +Cc1nc(N)c2c(C)c(C)n(CC(=O)N(C)C)c2n1 +CCC1CN(C(=O)C(C)C)c2cc(S(N)(=O)=O)ccc2O1 +CCn1nccc1NC(=O)Cc1cccc(C(F)(F)F)c1 +CC(C)(C)c1ccc(-c2cc(C(=O)NCCC#N)no2)cc1 +CC(Cc1ccccc1Br)NC(=O)N1CCC(CO)C1 +COc1ccc2c(CC(=O)c3ccccn3)ccnc2c1 +CN(C)c1c(Cl)cccc1NC(=O)c1ccc(S(N)(=O)=O)o1 +O=C(OCC1CCCO1)c1ncn(-c2ccccc2)n1 +Cc1ccc(CNC(=O)CSc2nc(=O)[nH]c3c2CCC3)cc1 +CCCc1noc(C2CCN(C(=O)c3ccc(Cl)cc3)CC2)n1 +CCN(CC)C(=O)C(C#N)Cc1cc(Cl)ccc1OC +CC(C)(O)CCc1ccc(C(=O)NCc2cc(C3CC3)[nH]n2)cc1 +CCNC(=O)NCC1CCN(c2ccc(F)c(F)c2)C1 +CC(CNC(=O)c1cc(-c2cccc(F)c2)no1)N1CCOCC1 +Cc1ncsc1CN(C)C(C)Cc1ccc(O)cc1 +CC(C)C(O)C1NCCc2c(Cl)ccc(Cl)c21 +O=C1CCC(COC(=O)CCc2ncc(-c3ccccc3F)o2)N1 +Cc1cc2nc(COC(=O)COc3ccc(C)c(C)c3)cc(=O)n2o1 +CC(C)c1ncc(C(=O)NC2CCCCCC2)c(N)n1 +COC(=O)C(NC(=O)Nc1cccc(Br)c1)C(C)C +CC(CO)(CO)C(=O)OCc1ccc(Br)cc1 +Cc1c(COC(C)C)cccc1NC(=O)NCc1ncc[nH]1 +COc1cc(C)c(C(=O)N(C)CCOc2ccc(F)cc2)cc1OC +COc1cccc(COC2CCCN(C(=O)c3ccccc3F)C2)c1 +CCOc1cc(C#N)c(Br)c(Br)c1OC +CN(C(=O)c1cccc(Cl)c1)C1(C#N)CCCC1 +O=C(CCCn1ccc2cc(Cl)ccc21)NCCc1cscn1 +CC(c1ccccc1F)N(C)c1ncccc1C#N +CCc1cccc(C)c1NC(=O)CNc1ccccc1OC +COc1ccc(CCNC(=O)Nc2nnc(-c3ccn(C)n3)o2)cc1 +N#Cc1nnn(-c2ccc(S(N)(=O)=O)cc2)c1C1CC1 +Cc1nn(C)c(C)c1Nc1ncnc2ccsc12 +CC(=O)c1c(C)nc(C)nc1SCc1nccn1CC(F)(F)F +CCNC(=O)C(C)NS(=O)(=O)c1ccc(N)cc1C +O=C(NCCN1CCOCC1)NCc1ccccc1-n1cccn1 +COC(C(=O)NC(C)(C)CC(N)=O)c1ccccc1 +CN(C)C(=O)Cn1c2c(ccc1=O)CCN(Cc1cnn(C)c1)CC2 +Cc1cccc(C)c1OCCNC(=O)c1ccco1 +CCOc1ccc(NC(=O)Cn2ncc3ccccc3c2=O)cc1 +CCC(Sc1ccccc1)C(=O)Nc1ccc2c(c1)CC(=O)N2 +Cc1csc(NC(=O)N2CCN(CC(=O)NC3CC3)CC2)n1 +CCCc1nc(CN2CC(n3nc(C)cc3C)C2)no1 +COc1ccc2c(c1)NC(=O)C21Nc2ccc(Cl)cc2C(=O)N1C +O=C(C1CCOCC1)N1CCN2C(=O)N(Cc3ccccc3)CC2C1 +CC(C)n1c(CCNC(=O)c2ccc(C#N)cc2)nc2cccnc21 +CCCCNC(=O)CSc1nnc(-c2ccc(N)cc2)n1C +CCN(CC)C(=O)c1c(-c2cccnc2)cnnc1N +COC(=O)c1ccccc1SCC(=O)Nc1ccc(Cl)cn1 +CC(NC(C)c1ccccc1N(C)C)C(=O)N1CCOCC1 +Cn1ccnc1COC(=O)c1ccn(C2CCCC2)n1 +Clc1ccc(OCc2nc(C3CC3)no2)cc1 +CC(C)C(=O)c1ccccc1NC(=O)c1cccc2c1OCC(=O)N2 +CCn1cc(C(=O)Oc2cc(OC)ccc2C(C)=O)cn1 +COc1ccc(OC(C)C(=O)Nc2cc(C)ccn2)cc1 +CCOCC(=O)Nc1ccc(C(N)=O)cc1Br +O=C(NCCn1nc(C(F)(F)F)cc1C1CC1)C1CC1 +Cc1ccccc1NC(=O)C(C)Sc1nnc(-c2cccnc2)o1 +COC(=O)Cn1cnc2cc(Cl)c(Cl)cc21 +CC(C)Oc1ncccc1CNC(=O)c1ccc[nH]c1=O +CN(C)c1cccc(C(=O)NCc2nnnn2C2CC2)c1 +CCS(=O)(=O)c1ccccc1C(=O)N1CCOCC1C +CC(=O)Nc1cc(C(=O)Nc2cccc(Cl)c2Cl)ccc1F +CCNC(=O)N1CCN(C(=O)CN2CCOCC2)CC1 +COc1ccc(CC(=O)Nc2cc(OC)c(OC)cc2C)cc1 +CN(CC(=O)NCCOc1ccc2c(c1)OCO2)c1ccc(F)cc1 +O=C(CCc1ccncc1)NCCc1nc2ccccc2[nH]1 +CNc1ncc(Br)cc1C(=O)Nc1ccc(Cl)cc1 +CC(C)(C)Oc1ccc(OC2CC2)c(S(N)(=O)=O)c1 +O=C(NCc1nnc2n1CCCC2)c1ccc2ccccc2n1 +CC(C)(C)CC(=O)N(Cc1cccnc1)Cc1ccco1 +CCn1cc(CN2CC(c3cc(C)ccc3C)OCC2C)cn1 +COc1cccc(C(=O)Nc2ccc3c(c2)CC(=O)N3)c1 +Cc1nn(C)c(C)c1OCC(=O)Nc1ccc(CCO)cc1 +COc1c(C)cc(C)cc1C(O)CN1CC(C)OC(C)C1 +O=C(NC1CC1)c1ccc(CNC(=O)c2cc(Cl)c[nH]2)cc1 +CCC(=O)Nc1cccc(NCc2c[nH]nc2-c2cccnc2)c1 +CC(C)N(CC(N)=O)C(=O)CN(C)C(=O)c1ccccc1 +Cc1cccc(NC(=O)c2ccc(C(N)=O)cc2)c1C +Cc1ccc(Sc2ncccc2C(=O)N2CCCC2)c(C)c1 +CCOc1ccc2c(c1)nc(CO)n2CCC(C)C +COCCCNC(=O)N(C)Cc1ccc(OC)c(O)c1 +COc1ccc(F)c(NC(=O)C2CC(=O)N(Cc3ccccn3)C2)c1 +O=C(Nc1cnc(Oc2ccccc2)nc1)c1ccccn1 +Cc1nccn1-c1ccccc1CNC(=O)c1nnc2n1CCCC2 +Cc1cc(CNCC(=O)N2CCN(c3ccccc3)CC2)ccc1F +COc1cccc(CN2CC(C(=O)N3CC(C)OC(C)C3)CC2=O)c1 +O=C(NCCCn1cccn1)C1COc2ccccc2C1 +CN(CC(=O)Nc1ccc(Cl)cc1)C(=O)C1CCCC1 +CCN(CC)C(=O)CCC(=O)Nc1nc2ccc(C)cc2s1 +CCOc1cccc(CNC(=O)C2CCC(=O)N2)c1 +COCCn1cc(NC(=O)NC(C)c2cccnc2)cn1 +COCC(NC(=O)C1CC1c1cc(F)ccc1F)C(N)=O +Cn1c(NC(=O)c2ccsc2)nc2cc(Cl)ccc21 +O=C(COC(=O)c1n[nH]c2ccccc12)c1ccc[nH]1 +N#Cc1cc2n(n1)CCCN(c1nccc(N3CCCC(O)C3)n1)C2 +CC(C)c1noc(CN2CCN(C(=O)c3ccncc3F)CC2)n1 +CCc1nc2n(n1)CCCC2NC(=O)COc1cccc(C)c1 +CCCC(C)NC(=O)C1CCN(C(=O)C(C)(C)C)CC1 +CCc1cccc(NC(=O)COC(=O)Cc2cn3ccsc3n2)c1 +CSc1nnc(Cc2ccc(F)cc2)c(=O)n1N +Cc1c(NC(=O)CNC(N)=O)cccc1OCC(F)(F)F +Cc1ccsc1CN(Cc1cccc2cccnc12)CC(C)O +O=C1N=C(CN2CCCC2)N=C2c3ccccc3CC3(CCCC3)C12 +Cc1cccn2cc(CSc3nnc(C)n3N)nc12 +Cc1ccc(-c2nsc(C(=O)NCc3ccco3)c2N)cc1 +COc1ccc(NC(=O)Nc2ccccc2)c(OC)c1 +O=C1NCC(c2ccc(Cl)cc2)Cc2[nH]c(-c3n[nH]c(=O)[nH]3)nc21 +CCOC(C)C(=O)Nc1cc(NC(C)=O)ccc1F +COCCNC(=O)c1ccc(-c2ccc(F)cc2)nc1N +Cc1noc(C)c1-n1c(CCNc2ccccc2)n[nH]c1=O +COc1ccc(-c2c(C)sc3nc(C)c(N)n23)cc1OC +O=C(COC(=O)c1cccs1)Nc1ccc(Cl)cn1 +COCCCC(=O)Nc1cccc(Cl)c1OC +Brc1cc2c(cc1COc1ccccn1)OCCO2 +CCS(=O)(=O)N(C)C(C)Cc1ccc(C)cc1 +Nc1cc(Br)cnc1OCc1ccccc1 +CC1CN(CCNC(=O)Cc2c[nH]c3cc(F)ccc23)CC(C)O1 +COc1cc2c(cc1OC)C(CNC(C)=O)NCC2 +COc1cc(C(=O)NC(C)c2nc3ccccc3o2)nn1C +CC1NC(c2ccccc2)COC1c1ccccc1 +CCCC1CN(C(=O)Nc2ccccc2-c2ccncc2)CCO1 +Cc1c(N)cccc1S(=O)(=O)NC1CCCC(C)C1 +Cc1ccc(S(=O)(=O)Cc2c(C)noc2C)cc1 +COC(=O)NCC(=O)N(Cc1ccccn1)C1CC1 +C=CCOC(=O)C(NC(=O)c1ccccc1)=C(C)C +CCN(C(=O)c1c(OC)cccc1OC)c1ccccc1 +COc1ccc(Cc2nnc3sc(-c4ccnn4C)nn23)cc1 +CC(C)S(=O)(=O)c1ccc(C(=O)C2CCCC2)cc1 +CCOC(=O)CC(C)CNC(=O)NC1CCCC(C)C1 +Cc1ccc(N(CCC#N)C(=O)c2ccc3c(c2)OCO3)cc1C +Cc1nscc1C(=O)NCc1ccc(F)cc1 +O=C1CCCc2cc(C(O)c3ccc(Cl)cc3)ccc2N1 +CCc1onc(C)c1C1CCCN1S(=O)(=O)c1ccccc1C +CCN(CC)C(=O)Nc1ccc(S(=O)(=O)NC(C)C)cc1 +COc1ccnc(N(C)Cc2csc(C)n2)n1 +Cc1ccc(NC(=O)c2nc3cccnc3s2)cc1C +CCN(Cc1ccccc1)C(=O)C(C)N1CCOC(C(N)=O)C1 +CCN(CC1CCOC1)C(=O)c1ccc2[nH]nnc2c1 +CCNC(=O)c1ccc(CNC(=O)NCC(C)(C)C(N)=O)cc1 +CCN1CC(C(=O)Nc2c(C)n(C)n(-c3ccccc3)c2=O)CC1=O +C=C(C)Cn1c(-c2ccc3c(c2)OCCO3)ccc(C#N)c1=O +Cc1cc(C)c(NC(=O)c2ccn(C)c(=O)c2)c(C)n1 +COc1ccc(OC)c(-c2c(C(C)C)n[nH]c2N)c1 +CC(C)CCNC(=O)Cc1csc(NC(=O)c2ccsc2)n1 +Cc1nc(CNC(=O)CCCc2ccc3c(c2)CC(=O)N3)c(C)s1 +CCc1onc(C)c1NC(=O)C1CCN(c2ccc(Cl)cc2)C1=O +Cc1ccc(CN(C)c2ncnc3ccc(F)cc23)cc1 +O=C(OC(c1ccncc1)c1ccc(F)cc1)c1cccc2cn[nH]c12 +CCOC(=O)c1c(C)oc2ncnc(N(C)C3CCCCC3)c12 +CC1(C)CCC(CNC(=O)C2CNC(=O)C2)CC1 +Cc1cccc(-n2nc(-c3ccccc3F)c(C#N)c2N)n1 +Cc1nnc(SCc2ccc(F)c3cccnc23)n(N)c1=O +CC(C)N(CC(N)=O)C(=O)c1ccc(F)cc1N +CC(C)NC(=O)Nc1cccc(Cl)c1N(C)C +CCN(c1ccccc1)S(=O)(=O)c1cccc(C(N)=O)c1 +Cc1csc(NC(=O)c2n[nH]c(=O)c3ccccc23)n1 +COC(=O)c1c(C)[nH]c(C(=O)Nc2ncc(C)s2)c1C +COc1ccccc1NCCOc1ccccc1OC +NC(=O)Cc1ccc(NC(=O)Cn2c(=O)oc3ccccc32)cc1 +COC(=O)C1CN(c2cc(Cl)ccc2OC)CCC1=O +C=CCNC(=O)c1cccc(S(=O)(=O)N(C)Cc2cnn(C)c2)c1 +CC(=O)Nc1cc(NC(=O)c2ccsc2)ccc1F +CC(C)Cn1cc(NCc2ccc(F)c(F)c2)cn1 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+Cc1nn(C)c(C)c1CCC(=O)Nc1cccc2cn[nH]c12 +Cc1nn(-c2ccccc2)cc1CCCNC(=O)c1cccc(F)c1 +Cc1nc(CNC(=O)C(C)c2cc3ccccc3o2)c(C)s1 +CNc1nc(-c2ccncc2)c(C(C)=CC(=O)OC)s1 +O=C(c1cccc(Br)c1)c1ccccn1 +O=C(c1cnc2scc(-c3ccccc3)n2c1=O)N1CCCC1 +CCc1cc(N2CCn3nc(C#N)cc3C2)nc(N2CCOCC2)n1 +NC(=O)c1ccsc1NC(=O)COC(=O)c1ccccc1 +CC(=O)NC(C(=O)Nc1nc2c(ccc3ccccc32)s1)C(C)C +Cc1ccc(N2CCC(C(=O)NCc3ncn(C)n3)C2=O)cc1 +COCc1ccccc1CNC(=O)c1ccc(-n2ccnc2)cc1 +O=C1CSc2nc(C34CC5CC(CC(C5)C3)C4)nn21 +COc1ccc(OCCOc2ccc[nH]c2=O)cc1 +CCn1cc(CN(C)C(=O)Nc2ccc(OC)cc2)cn1 +Cc1ccccc1Cc1c(C)c2c(C)n[nH]c2oc1=O +Cc1ccc(NCC=Cc2ccc(C#N)cc2)cc1-n1cnnn1 +Cc1cc(C)n(CC(=O)N(c2cccc(F)c2)C2CCOCC2)n1 +COc1ccc2c(c1)CC(C(=O)NCc1cccc(F)c1)CO2 +CC(C(=O)N1CCOC(c2cccc(OC(F)F)c2)C1)C1CC1 +Cc1cccc(NC(=O)C2CCN(S(=O)(=O)N(C)C)CC2)c1 +O=C(NCc1ccc(F)cc1)N(Cc1ccco1)CC1CCCO1 +O=c1oc2cccnc2n1CCN1CCN(c2ncccn2)CC1 +CS(=O)(=O)N1CCCC1C(=O)NC(c1ccccc1)C1CC1 +Cc1noc(CCNC(=O)CCc2ccc(F)cc2)n1 +CCCNC(=O)C1CCN(C(=O)C(OC)c2ccccc2)CC1 +CCn1nc(C)c(NS(=O)(=O)c2cnn(C(C)C)c2)c1C +CCc1nc(CC(=O)N2CCN(C(=O)c3ccncc3)CC2)cs1 +CCNc1nc2ccccc2nc1C(C#N)C(=O)OC +CN(CC#CCNC(=O)C(C)(C)C)Cc1ccccc1 +O=C(CN1C(=O)COc2ccccc21)Nc1cccc2ncccc12 +O=C(c1ccc(F)cc1)N(Cc1ccco1)CC(F)(F)F +CCOC(=O)CCN1CCN(C(=O)C23CC4CC(CC(C4)C2)C3)CC1 +Cc1ccncc1NC(=O)COc1ccc2ccccc2c1 +CCCCC1C=CCN1C(=O)c1sccc1S(N)(=O)=O +CC(C)N(Cc1cccnc1)C(=O)Nc1ccc2c(c1)COC2 +O=C(NCCc1cccc(O)c1)c1ccc(-c2cscn2)cc1 +CC(CC#N)N(C)Cc1ccc(F)cc1C(F)(F)F +CN(C)C(=O)c1nccc(OC(C)(C)C)c1OC1CC1 +Cc1n[nH]cc1CNS(=O)(=O)c1cccc(C(F)(F)F)c1 +COC(C)(C)c1noc(Cc2nc(-c3ccccc3)oc2C)n1 +CC(C)N(CC(F)(F)F)C(=O)Cn1cnc2c(cnn2C)c1=O +CCCCS(=O)(=O)N(C(C)=O)c1ccc(OC(C)=O)cc1 +O=C(Nc1ccc(Cl)cc1C(=O)Nc1ccncc1)c1ccco1 +Cc1nc2cc(N(C)CC(C)C#N)c(N)cc2s1 +CNC(=O)c1ccc(NCc2ccccc2Cl)c(C)c1 +Cc1noc(CCC(=O)OCc2cccc(Br)c2C)n1 +Cc1cccc(NS(=O)(=O)N2CC(C)OC(C)C2)c1C +COc1cccc(C(=O)N(C)c2cccc(C#N)c2)c1F +CCC1CCC(NC(=O)c2ccccc2SCC(N)=O)CC1 +Cc1c(C(=O)NCCCN2CCOCC2)cnn1-c1ccccc1F +Cc1nonc1CC(=O)Nc1ccccc1Sc1c(C)n[nH]c1C +O=C1N(Cc2ccccc2Cl)c2ccccc2C12OCCCO2 +COc1ccc(OC)c(NCC(=O)c2ccccc2)c1 +Cc1ccsc1C(=O)N1CC2CC1(C(=O)NCc1ccco1)C2 +CC(C)NC(=O)c1ccc(Cl)c(S(=O)(=O)N2CCOCC2)c1 +CCOCCC(=O)N1CC(=O)Nc2cc(Br)ccc21 +CC(C)C(=O)NC1CC2CCC1N2C(=O)c1cccc(C#N)c1 +CN1CCN(C(=O)c2ccccc2F)C(c2ccccc2)C1 +Cc1c(C(=O)N2CCC(c3ccccc3)C2)sc2nc[nH]c(=O)c12 +Cc1ccc(CN(C)C(=O)Nc2cccc(N3CCNC3=O)c2)cc1 +Cc1nc(C(C)NC(=O)CCc2c[nH]c3ccccc23)n[nH]1 +COC(=O)C(C)(C)NC(=O)c1cc(-c2ccc(C)cc2)no1 +Cc1noc(NCc2cccc(-c3cccnc3)c2)n1 +Cc1ccccc1-c1noc(=O)n1CCS(=O)(=O)c1ccccc1 +O=C(N1CCN(c2ccccc2)CC1)C12CC3CC(CC(O)(C3)C1)C2 +CN1C(=O)CC(C(=O)Nc2ccc(Cl)cc2F)C1c1cccnc1 +CC(NC(=O)Nc1cnc(C2CC2)nc1)C1COc2ccccc21 +Cc1ccccc1C1(CNC(=O)NCCCc2c(C)noc2C)CC1 +O=C(Cc1c(F)cccc1Cl)OCn1nnc2ccccc2c1=O +O=C(CCC(=O)N(CC(F)(F)F)C1CCOCC1)c1ccccc1 +Cc1csc(N2CCN(C(=O)C(C)Sc3ccccn3)CC2)n1 +CC(C1CC1)n1nccc1NC(=O)Cn1cnc(C2CCC2)cc1=O +NC(=O)c1cccc(CNc2ccc(C(F)(F)F)cc2)c1 +Nc1cc(Cc2cccc(Br)c2)nn1CCO +CN(CC(F)(F)F)C(=O)C(Cc1ccccc1)N1CCCOC1=O +CC1CCCC(NC(=O)CN2CCN(Cc3cccn3C)CC2)C1 +CC(C)C1(C)Nc2cc3c(cc2N(CCO)C1=O)CCCC3 +CC1CCCC(CNC(=O)C(C)NC(=O)C2CCCCC2)C1 +Cc1cc(C)n2nc(C(=O)NCC(C)n3cncn3)nc2n1 +O=C(c1c[nH]nc1C1CCCCC1)N(CCCO)Cc1cccs1 +O=C(NCCc1cccc(F)c1)c1cc(F)ccc1F +CCNC(=O)CCCC(=O)Nc1ccc(C)c(S(C)(=O)=O)c1 +O=C(Nc1cc2c3c(c1)CCC(=O)N3CCC2)C1CCCC1 +O=C(NCc1ccccc1CO)c1cccn(Cc2ccccc2)c1=O +CCOC(=O)Cn1c(C)c(Br)c(COC)c(C#N)c1=O +OCc1ccnc(Cc2ccc(F)cc2Cl)n1 +Nc1c(C(=O)NC2CCCC2)nnn1-c1cccc(Cl)c1 +CC(C)(C)OC(=O)NCCNC(=O)Cc1ccccc1O +COc1ccccc1CNc1nc(N2CCCC2)nc2c1cnn2C +CCCC(NCc1ccc(Cl)cc1)C(=O)OC +CC1(NC(=O)c2ccc3c(c2)OCC(=O)N3)Cc2ccccc2C1 +Cn1cc(NC(=O)c2ccccc2OCC2CCCO2)cn1 +Cc1ccc(O)c(NC(=O)c2noc3c2CCC3)c1 +CCCCN(CC)C(=O)C1CCCN(c2ncnc3onc(C)c23)C1 +CCOc1ccccc1OS(=O)(=O)c1c(F)cccc1F +CN(C)c1ncc(Br)c2cc(N)ccc12 +COc1c(C(=O)N2CCC(Oc3cccc(Cl)c3)C2)c(C)nn1C +CC1CN(C(=O)Cc2ccccc2C(F)(F)F)CCC1(O)C1CC1 +CC(C)c1nc(Cn2cnc(C3CCC3)cc2=O)cs1 +CCN(CCO)c1ncnc(Nc2ccc(F)c(F)c2)c1N +CN(CCOc1cccc(F)c1)c1ncnc2c1cnn2C +COc1cc(C(C)=O)ccc1OC(=O)CCc1ccccc1 +CCOc1ccc(C(=O)Nc2ccccc2C(=O)NC(C)(C)C)cn1 +CC(C)(C)C(=O)Nc1nc(CC(=O)NCc2ccccn2)cs1 +CCc1nnc(-c2ccc(S(=O)(=O)Nc3cc(C)ccc3C)o2)o1 +CC1c2ccsc2CCN1C(=O)Cc1cn2ccsc2n1 +CCN(CCO)C(=O)c1ccc(NC(=O)C2CC2)cc1 +CN(C)C(=O)COCC12CCCOC1CCN(C(=O)N(C)C)C2 +O=C(Cc1c[nH]c2ccccc12)N1CCCC1c1ccncc1 +Cc1nc(CNC(=O)c2oc3ccccc3c2C)cs1 +COc1cc(NC(=O)N2CC(C)CC(C)C2)cc(OC)c1 +Cn1c(-c2cccs2)nn(CCNC(=O)C2CCCCC2)c1=O +O=C(NC1CCN(C(=O)C2CC=CC2)CC1)c1ccccc1 +COC(=O)C1=C(C)Nc2nnnn2C1c1cc(C)ccc1C +CCC(=O)Nc1nn(C)c2c1C(c1ccco1)CC(=O)N2 +CC(NC(=O)CC(F)(F)F)c1ccc2[nH]c(=O)[nH]c2c1 +CC(=O)Nc1ccc(-c2ccc(S(=O)(=O)N(C)C(C)C)cc2)cc1 +O=C(c1nn(-c2ccccc2)cc1O)N1CCN(c2ccccc2)CC1 +CCN(CC)S(=O)(=O)N1CCN(C(=O)C2CCCCC2)CC1 +C=C(C)CSc1nnc(N2CCCC2)n1Cc1ccco1 +N#CCCN(Cc1ccccn1)Cc1ccc(-c2ccccc2)o1 +CCSc1nnc(C2CCN(C(=O)N3CCOCC3)CC2)n1C +COCC(=O)N1CCN(C(=O)NCC(C)(C)c2ccc(C)cc2)CC1 +Cc1ccc(C)c(SCC(=O)Nc2cccnc2)c1 +COc1cccc(OC)c1C(=O)Nc1cc(F)cc(F)c1 +Cc1ccc(S(C)(=O)=O)cc1C(=O)NCCOc1cccnc1 +Cc1c(-c2noc(-c3cccc(F)c3)n2)nnn1-c1ccc(F)cc1 +CCCn1nc(C(=O)Nc2nnc(CC(C)C)s2)ccc1=O +Cc1nc(C(C)C)sc1C(=O)NC1CCN(c2ncccn2)CC1 +C#CCN1CCN(C(=O)CNc2ccc(F)cc2OCC2CC2)CC1 +O=S1(=O)N=C(NCCCn2ccnc2)c2ccccc21 +CC(C)Oc1ccccc1NC(=O)CC(C)C(N)=O +CC(=O)c1ccc(S(C)(=O)=O)c(N2CCCC(n3cccn3)C2)c1 +COC(=O)CCCNC(=O)c1[nH]nc(C)c1Br +CCOC(C)c1nccn1CC(=O)NCc1sccc1C +CN(CCc1cccc(Cl)c1)S(=O)(=O)CCCO +Cc1nn(C)c(C)c1C(=O)Nc1nnc(C(C)(C)C)s1 +O=C(Nc1cc2c(cc1Br)OCCO2)c1ccsc1 +CC(C)(C)CC(=O)NCc1nc(-c2cccs2)no1 +Cc1ccc(S(=O)(=O)NCCC(=O)N2CCN(C)CC2)cc1C +CC(C)N(Cc1ccccc1)C(=O)NCCN1CCOCC1 +CC(C)C(C)NC(=O)CNC(=O)c1cccc(F)c1 +CN(C(=O)CCc1cccc(F)c1)c1ccc(F)c(F)c1 +CCN(Cc1cccc(F)c1F)CC1COc2ccccc2O1 +CCC(C)NC(=O)C(CC(C)C)NC(=O)c1ccccc1C +CC(=O)C(C)CSc1nnc(-c2c[nH]c3ccccc23)n1C1CC1 +Cc1cnc(C(=O)Nc2cccc3cnccc23)cn1 +Cn1ccnc1C(NC(=O)Cc1ccccc1F)c1ccccc1F +CNC(=O)CN(C)S(=O)(=O)c1c(C)c(Cl)cc(C)c1Cl +CC1CN(C(=O)CCc2cnn(C)c2)c2ccccc21 +Cc1cccc(C(=O)NCCNC(=O)CC2(O)CCCC2)c1 +Oc1cc2c(cc1F)CCNC2COc1ccccc1 +COc1ccc(C(O)CCCC(=O)N2CCOCC2)cc1F +CCCCN(C)C(=O)C(NC(=O)c1ccccc1)c1ccccc1 +CCC(=O)N1CCN(c2nc3c(C)ccc(C)c3s2)CC1 +O=C(NC1(c2cccc(Cl)c2)CC1)c1cccnc1 +Cc1c(C(=O)NC(C)(C)c2ccccc2)cnn1C +CCCc1nc(COC)c(-c2csc(NCC)n2)s1 +O=C(c1ccccc1Br)n1cccn1 +CCN(CC)C(=O)CCC(=O)N1CCOc2ccc(OC)cc21 +CCCC(C)N(C)C(=O)COc1cccc(C(N)=O)c1 +CCCN(CCc1cccc(F)c1)C(=O)c1cc(C)no1 +Cc1cc(C(=O)NCCc2cccc(O)c2)c2c(C)nn(C)c2n1 +CCCCN(C)S(=O)(=O)NC(C)c1ccc2c(c1)NC(=O)CO2 diff --git a/Experiments/BBBP/running utils/vocab.csv b/Experiments/BBBP/running utils/vocab.csv new file mode 100644 index 0000000000000000000000000000000000000000..a8d112ae53e12daec50e4a32374afc22776e5794 --- /dev/null +++ b/Experiments/BBBP/running utils/vocab.csv @@ -0,0 +1,2787 @@ +,Functional grp name,SMARTS,Smiles +0,Acid halides,"[F,Cl,Br][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +1,Acid azides,"[CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C=O +2,Sulphonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[Cl,Br]",*S(C)(=O)=O +3,Sulphonyl azides,"[Sv6X4](=[OX1])(=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",*S(=O)=O +4,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +5,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O +6,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1 +7,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O +8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1 +9,Thioesters,[CX3](=[SX1])[SX2],SC=S +10,Haloalkanes,"[CX4][Cl,Br,I]",*C +11,Dialkylsulfates/ sulfonates,"[$([#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6]),$([#6][Sv6X4](=[OX1])(=[OX1])[OX2][#6])]",* +12,N-Trihalomethyl imides,"[CX3](=[OX1])[NX3]([CX4]([Cl,Br,I])([Cl,Br,I])[Cl,Br,I])[CX3](=[OX1])",*C(*)(*)N(C=O)C=O +13,Quinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]",* +14,Hydroquinones and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1][cR1][cR1]([OX2][#1,CX4])[cR1][cR1]1",*Oc1ccc(O*)cc1 +15,Catechols and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1]([OX2][#1,CX4])[cR1][cR1][cR1][cR1]1",*Oc1ccccc1O* +16,"α, β-Unsaturated aldehydes, amides, esters and ketones","[$([CX3]([#6,$([NX3]([CX3]=[OX1])([#6])[#6]),$([OX2]([CX3]=[OX1])[#6]);!$([OH][CX3]=[OX1]);!$([O-][CX3]=[OX1])])(=[OX1])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX3H1](=[OX1])[CX3]([#6,#1])=[CX3])]",* +17,"Precursors of α, β-unsaturated aldehydes, amides, esters and ketones (1)","[$([CX4]([OX2])([OX2])([#6,#7,#8])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX4H1]([OX2])([OX2])[CX3]([#6,#1])=[CX3])]",* +18,"1,3-Diketones","[CX4,a!r0][CX3](=[OX1])[CH2][CX3](=[OX1])[CX4,a!r0]",*C(=O)[CH2]C(*)=O +19,Aldehydes,"[CX3]([H])(=[OX1])[#1,CX4,a!r0]",*C([H])=O +20,Ketones,"[CX4,a!r0][CX3](=[OX1])[CX4,a!r0]",*C(*)=O +21,Formaldehyde donors,"[$([NX3][CH2][NX3]),$([NX3][CH2][OX2]),$([CX4]([F,Cl,Br,I])([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])[CH2][OH1])]",* +22,Precursors of aldehydes and ketones,"[CX4]([OX2])([OX2])([CX4,a!r0])[CX4,a!r0]",*C(*)(O)O +23,Enol precursor of aldehydes and ketones,"[CX3]=[CX3]([#6,#1])[OX2]",*C(=C)O +24,Aromatic primary and secondary amines,"[a!r0][$([NX3H2]),$([NX3H1][CX4,a!r0])]",** +25,N-Haloimides,"[CX3](=[OX1])[NX3]([Cl,Br])[CX3](=[OX1])",*N(C=O)C=O +26,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl +27,Disullides,"[CX4,a!r0][SX2][SX2][CX4,a!r0]",*SS* +28,Phenyl carbonates,"c1ccccc1[OX2][CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)Oc1ccccc1 +29,Epoxides,[CX4]1[CX4][OX2]1,C1CO1 +30,1.2-Dicarbonyls,"[CX4,a!r0][CX3](=[OX1])[CX3](=[OX1])[#1,CX4,a!r0]",*C(=O)C(*)=O +31,Thiazolones,"[$([SX2]1[CX3]([CX4,a!r0])=[CX3]([CX4,a!r0])[CX3](=[OX1])[NX3]1([CX4,a!r0])),$([sX2]1[cX3]([CX4,a!r0])[cX3]([CX4,a!r0])[cX3](=[OX1])[nX3]1([CX4,a!r0]))]",* +32,"1, 2-Diamines","[CX4,a!r0][NX3H1][CX4][CX4][NX3H1][CX4,a!r0]",*[NH]CC[NH]* +33,Quaternary ammonium cation,"[NX4+]([CX4,a!r0])([CX4,a!r0])([CX4,a!r0])[CX4,a!r0]",*[N+](*)(*)* +34,Activated N-heterocycle halides,"[$(n1c([F,Cl])ncnc1),$(n1c([F,Cl])ccnc1),$(n1c([F,Cl])nccc1)]",* +35,Aromatic sulphuric acids and salts,"[a!r0][Sv4X3](=[OX1])[$([OH]),$([O-])]",*S(*)=O +36,Iso(thio)cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +37,Acid imides,"[NX3]1([#1,#6])[CX3](=[OX1])[CX3]([!R])=[CX3]([!R])[CX3]1(=[OX1])",*C1=C(*)C(=O)N(*)C1=O +38,Activated N-heterocycles,"[$(n1c([F,Cl,$([CX2]#[NX1])])nccc1),$(n1cnccc1([F,Cl,$([CX2]#[NX1])])),$(n1cncnc1([F,Cl,$([CX2]#[NX1])]))]",* +39,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +40,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC +41,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1 +42,Aldehydes and precursors,"[$([#1,#6;!$(C=C);!$(C#C)][CX3]([H])(=[OX1])),$([CX4;H1]([OX2])[OX2])]",* +43,"α, β-Unsaturated carbonyls","[CX3]=[CX3][CX3](=[OX1])[$([OX2]([CX3]=[OX1])[!#1]),$([#1][CX3]=[OX1]),$([NX3H2]([CX3]=[OX1])),$([NX3]([CX3]=[OX1])),$([CX4][CX3]=[OX1])]",*C(=O)C=C +44,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +45,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH] +46,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1 +47,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1 +48,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1 +49,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH] +50,Thiols,[#16X2H1],[SH] +51,Disulfides,*[#16X2][#16X2]*,*SS* +52,Diaryl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[a!r0],*C(=O)OOC(*)=O +53,Arylacyl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[A],*C(=O)OOC(*)=O +54,Haloamides,"[#6][CX3](=[OX1])[NX3]([F,Cl,Br,I])[#6]",*N(C)C(C)=O +55,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH] +56,"1,2-Dihydroxy aromatic compounds",[OH1]aa[OH1],[OH]*:*[OH] +57,"1,4-Dihydroxy aromatic compounds",[OH1]aaaa[OH1],[OH]*:*:*:*[OH] +58,2 or 4-Hydroxysubstituted alkylphenyl ether,"[$(c1c([OX2][CX4])c([OH1])ccc1),$(c1c([OX2][CX4])ccc([OH1])c1)]",* +59,Aromatic amines,"[a!r0][$([NX3H2]),$([NX3H1][#6])]",** +60,Aromatic amines precursors,"[$([a!r0][NH1][CX3](=[OX1])),$(c1c([NX2]=[NX2][a!r0])ccc([$([NX3]([CX4])([CX4])),$([NX3H1][CX4]),$([NH2]),$([OH1])])c1)]",* +61,Alkyl or aryl sylfonyl halides,"[CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +62,Sulfonamides,"c1c([Sv6X4](=[OX1])(=[OX1])[NX3H1][$([#1]),$([CX4]),$([a!r0])])ccc([NX3H2])c1",*[NH]S(=O)(=O)c1ccc([NH2])cc1 +63,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S +64,Hydrazines,"[#6&!$([CX3]=[OX1,SX1,NX2])][NX3H1][NX3H2,$([NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])])]",*[NH]C +65,Aromatic nitro (general),"[a!r0][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",** +66,Aromatic amine (general),[a!r0][NX3H2],*[NH2] +67,Three-membered heterocycles (general),"[NX3H1,SX2,OX2]1[CX4][CX4]1",*1CC1 +68,Nitroso (general),[NX2]=[OX1],N=O +69,Unsubstituted heteroatom-bonded heteroatom (general),"[$([NX3H2]-[#7]),$([NX3H2]-[#8]),$([OX2H1]-[#7]),$([OX2H1]-[#8])]",* +70,Azo-type (general),[NX2]=[NX2],N=N +71,Aliphatic halide (general),"[CX4][Cl,Br,I]",*C +72,Polycyclic aromatic system (general),"[$([aR3]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))])]",* +73,Aromatic nitroso (specific),[a!r0][NX2]=[OX1],*N=O +74,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O +75,Nitrosamine (specific),"[OX1]=[NX2][NX3]([#6,#1])[#6,#1]",*N(*)N=O +76,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1 +77,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1 +78,Azide (specific),"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +79,Diazo (specific),"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +80,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N +81,Aromatic hydroxylamine (specific),[a!r0][NX3H1][OH1],*[NH][OH] +82,Aliphatic halide (specific),"[Cl,Br,I][$([CX4]);!$([CX3](=[OX1,SX1,NX2]));!$([CH2][CH2][SX2,NX3])]",** +83,Carboxylic acid halide (specific),"[Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +84,Nitrogen and sulphur mustard (specific),"[Cl,Br,I][CH2][CH2][SX2,NX3]",*[CH2][CH2]* +85,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1 +86,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1 +87,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O +88,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O +89,Aliphatic N-nitro (additional),"[NX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1][O-]))]",*N +90,Diazonium (additional),"[$([a!r0][NX2+]#[NX1]),$([a!r0][NX2]#[NX1])]",* +91,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +92,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH] +93,1-Aryl-2-monoalkyl hydrazine (additional),[a!r0][NX3H1]-[NX3H1][CX4],*[NH][NH]C +94,Aromatic methylamine (additional),[a!r0][NX3;H1][CH3],*N[CH3] +95,Aromatic hydroxylamine ester (additional),[a!r0][NH][OX2][CX3](=[OX1]),*[NH]OC=O +96,Polycyclic planar system (additional),[*R1]1[*R2]2=[*R1][*R1]=[*R1][*R1]=[*R2]2[*R1][*R2]3=[*R1][*R1]=[*R1][*R1]=[*R2]13,*1*2=**=**=*2**2=**=**=*12 +97,Acyl halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +98,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +99,Monohaloalkene,"[CX3]([CX4,#1])([F,Cl,Br,I])=[CX3]([CX4,#1])[!F!Cl!Br!I]",*C(*)=C(*)* +100,S or N mustard,"[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +101,Propiolactones or propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +102,Epoxides and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +103,Aliphatic halogens,"[CX4;!H0][Br,Cl,I]",*C +104,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O +105,Simple aldehyde,"[CX3]([H])(=[OX1])[#1,#6&!$([CX3]=[CX3])]",*C([H])=O +106,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN +107,Aliphatic azo and azoxy,"[$([C,#1][NX2]=[NX2][C,#1]),$([CX3]=[NX2+]=N),$([CX3]=[NX2+]=[NX1-]),$([CX3-][NX2+]#[NX1]),$([CX3][NX2]#[NX1]),$(C[NX2]=N(=O)[*]),$(C[NX2]=[N+]([O-])[*])]",* +108,Isocyanate and isothiocyanate groups,"[NX2]=[CX2]=[OX1,Sv2X1]",*=C=N +109,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +110,Thiocarbonyl,"[$([NX3][CX3](=[Sv2X1])[NX3]),$([CX3;!$(C[OH]);!$(C[SH]);!$(C[O-]);!$(C[S-]);!$(CO[#6])](=[Sv2X1])[NX3])]",* +111,Heterocyclic polycyclic aromatic hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +112,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O +113,Azide and triazene groups,"[$([NX2!R]=[NX2!R][NX3!R]),$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",* +114,Aliphatic N-nitro group,"[NX3]([#1,C])([#1,C])[$([NX3+](=[OX1])[O-]),$([NX3](=O)=O)]",*N(*)* +115,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC +116,Aromatic nitroso group,[a!r0][NX2]=[OX1],*N=O +117,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +118,Coumarins and furocoumarins,"[$(c1cccc2c1oc(=O)cc2),$(C1=CC(=O)OC2=CC=CC=C12),$(C1=CC(=O)Oc2ccccc12)]",* +119,Halogenated benzene,"c1ccccc1[$([Br,Cl,F,I]);!$([Br,Cl,F,I]aa[Br,Cl,F,I]);!$([Br,Cl,F,I]aaa[Br,Cl,F,I]);!$([Br,Cl,F,I]aa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aaa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aa([OH])a([OH])aa[OH])]",*c1ccccc1 +120,Halogenated PAH,"[Br,Cl,F,I][$([cR1]1[cR1][cR1][cR1][cR1][cR1]1-[cR1]2[cR1][cR1][cR1][cR1][cR1]2),$([cR1]1[cR1][cR1][cR1][cR2]2[cR2]1[cR1][cR1][cR1][cR1]2)]",** +121,Halogenated dibenzodioxins,"[OR1]1[CR2]2=[CR1][CR1]=[CR1][CR1]=[CR2]2[OR1][CR2]3=[CR1][CR1]([F,Cl,Br,I])=[CR1][CR1]=[CR2]13",*C1=CC=C2OC3=CC=CC=C3OC2=C1 +122,Primary and secondary aromatic amines,"[$([a!r0][NX3;H2]),$([a!r0][NX3;H1][CH3]),$([a!r0][NX3;H1][CH2][CH3])]",* +123,Tertiary aromatic amines,"a[NX3]([$([CH3]),$([CH2][CH3])])[$([CH3]),$([CH2][CH3])]",*N(*)* +124,Secondary aromatic acetamides and formamides,"[$([a!r0][NX3;H1][CX3;H1](=[OX1])),$([a!r0][NX3;H1][CX3](=[OX1])[CH3])]",* +125,Nitroarenes,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=O)(=O))]",** +126,Nitrosoarenes,[a!r0][NX2]=[OX1],*N=O +127,Arylhydroxylamines,"[a!r0][NX3;H1][OX2][#1,#6]",*NO* +128,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O +129,N-Nitroso-N-alkylamides,"[CX4,a!r0][CX3](=[OX1])[NX3]([CX4])[NX2]=[OX1]",*C(=O)N(C)N=O +130,N-Nitroso-N-alkylureas,"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[NX3H1][CX4,a!r0]",*[NH]C(=O)N(C)N=O +131,N-Nitroso-N-alkylcarbamates (aka urethanes),"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)N(C)N=O +132,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O +133,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O +134,Benzylic halides,"[a!r0][CH2][Cl,Br,I]",*[CH2]* +135,Oxiranes and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +136,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +137,Alkyl esters of sulfonic and sulphuric acids,"[$([CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,a!r0][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])])]",* +138,Alkyl esters of phosphonic and phosphoric acids,"[$([CX4,a!r0][Pv5X4](=[OX1])([OX2][$([CH3]),$([CH2][CH3])])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,#1][OX2][Pv5X4](=[OX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])])]",* +139,Mixed alkyl esters of thiophosphoric acid,"[CX4][OX2][Pv5X4](=[SX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])]",*OP(=S)(O*)OC +140,Haloethylamines,"[NX3]([#1,#6])([#1,#6])[CH2][CH2][Cl,Br,I,F]",*[CH2][CH2]N(*)* +141,Haloalkylethers,"[$([#6][OX2][CH2][CH2][Cl,Br,I]),$([#6][OX2][CH2][Cl,Br,I])]",* +142,α-Halocarbonyl or a-halohydroxy,"[$([CX3](=[OX1])[CH2][Cl,Br,I]),$([CX4!H0]([OH1])[CH2][Cl,Br,I])]",* +143,Haloamines,"[#6][NX3]([#6])[Cl,Br,I,F]",*N(C)C +144,Allylic halides and alkoxides,"[CX3]=[CX3][CH2][$([Cl,Br,I]),$([OX2])]",*[CH2]C=C +145,Halogenated methanes,"[CX4]([H,F,Cl,Br,I])([H,F,Cl,Br,I])([H,F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)* +146,Vinyl halides,"[CX3]=[CX3H1][Cl,Br,I]",*[CH]=C +147,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O +148,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S +149,Alkyl esters of phosphonic or sulphonic acids,"[$([CX4,a][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]),$([CX4,a][Pv5X4](=[OX1])([OX2][#1,CX4])[OX2][CX4])]",* +150,Aromatic nitro groups,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=[OX1])=[OX1]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +151,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +152,Aromatic mono- and dialkylamino groups,"[a!r0][$([NX3H1][CH3]),$([NX3H1][CH2][CH3]),$([NX3]([CH3])[CH3]),$([NX3]([CH3])[CH2][CH3]),$([NX3]([CH2][CH3])[CH2][CH3]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +153,Alkyl hydrazines,"[NX3]([CX4])([#1,CX4])[NX3]([#1,CX4])[#1,CX4]",*N(*)N(*)C +154,Alkyl aldehydes,"[$([CX3]([H])(=[OX1])[#1,CX4])&!$([CX3]([H])(=[OX1])[CX3]=[CX3])]",* +155,Monohaloalkenes,"[CX3]([CX4,#1])(Cl)=[CX3]([!F!Cl!Br!I])[CX4,#1]",*C(*)=C(*)Cl +156,"β-Haloethyl N, S - mustards","[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +157,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl +158,Propiolactones and propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +159,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1 +160,Aromatic and aliphatic substituted primary alkyl halides,"[F,Cl,Br,I][CH2][CX4,a]",*[CH2]* +161,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O +162,Aliphatic and aromatic epoxides,"[$([CX4]1[OX2][CX4]1),$([#6]1=[#6][#8]1)]",* +163,Activated halo- or nitropyridines,"[$(c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])cc1),$(c1([F,Cl,Br,I,$(N(=O)=O)])ncccc1([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)]))]",* +164,2-Halo- or 2-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncccn1",*c1ncccn1 +165,4-Halo- or 4-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncncc1",*c1ccncn1 +166,Activated 2-halo- or 2-nitropyrazines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])nc1",*c1cnc(*)cn1 +167,Halo- or nitro s-triazines,"c1nc([F,Cl,Br,I,$(N(=O)=O)])ncn1",*c1ncncn1 +168,Formaldehyde and thioformaldehyde,"[CH2]=[OX1,SX1]",*=C +169,Aliphatic aldehydes and thioaldehydes,"[CX4][CX3H1]=[OX1,SX1]",*=[CH]C +170,Aromatic aldehydes,[a][CX3H1]=[OX1],*[CH]=O +171,"α, β-Unsaturated carbonyl and thiocarbonyl compounds","C(C)(C)=CC=[OX1,SX1]",*=CC=C(C)C +172,"α, β-Unsaturated ketones and thioketones","[C;!r5]([C;!r5])=[C;!r5][C;!r5](C)=[OX1,SX1;!r5]",*=C(C)C=CC +173,α-Diketones and α-dithiones,"[#6]C(=[OX1,SX1])C(=[OX1,SX1])[#6]",*=C(C)C(=*)C +174,β-Diketones and β-dithiones,"[#6]C(=[OX1,SX1])[CX4]C(=[OX1,SX1])[#6]",*=C(C)CC(=*)C +175,"C-Nitroso compounds, iso(thio)cyanates, (thio)cyanate esters","[#6][$([NX2]=O),$(N=C=O),$(OC#N),$(SC#N),$(N=C=S)]",*C +176,Primary alkyl amines,[CH2][NH2],[CH2][NH2] +177,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3] +178,"α, β-Unsaturated alkoxy","[$(CC(C)=[CH][CH2][OH]),$(CC=C(C)[CH2][OH])]",* +179,Three-membered heterocycles derivatives,"[CH,CH2,CH3;!$([CH2]CC=[O,S])]([F,Cl,Br,I,$(OS(=O)(=O)[#6,#1]),$(OS(=O)(=O)O[#6,#1])])[#6]1[O,N,SX2][#6]1",**C1*C1 +180,Lactones and their thio analogues,"C1C(=[O,S])[O,S][CH2,CH]1",*=C1**C1 +181,Esters of aromatic and unsaturated alcohols and their thio analogues,"[$(C=C),$(C#C),a][CH2,CH][O,S][$([CH]=O),$([CH]=S),$(C(C)=O),$(C(C)=S)]",**** +182,Aryloxy (arylthio) containing unsaturated compounds,"[$(C=C),$(C#C),a][CH2,CH][O,S][a]",**** +183,Aliphatic N-(thio)nitroso compounds,"[CH2,CH3][NX3][NX2]=[O,S]",*NN=* +184,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1 +185,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +186,Activated alkene (Michael acceptor) (1),"[CH2,CH]=[CH][$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*[CH]=* +187,Activated alkene (Michael acceptor) (2),"[CH2]=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C +188,Activated alkene (Michael acceptor),"aC=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C* +189,Activated alkine,"C#C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C#C +190,Activated conjugated dienes,"[CH2,CH]=[CH]C=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C[CH]=* +191,Alkenes containing a gem-dihalo-substituted terminal double bond,"C=C([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)=C +192,Ortho-disubstituted benzenes,"c1c([O,NH2,NH])c([O,NH2,NH])ccc1",*c1ccccc1* +193,Para-disubstituted benzenes,"c1c(=[O,NH2,NH])ccc(=[O,NH2,NH])c1",*=c1ccc(=*)cc1 +194,Haloanhydrides,"[F,Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +195,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1 +196,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21 +197,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +198,Phosphorus halogen derivatives (1),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#6])[#6]",*P(C)(C)=O +199,Phosphorus halogen derivatives (2),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#6]",*P(C)(O)=O +200,Phosphorus halogen derivatives (3),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#8]",*P(O)(O)=O +201,Phosphorus halogen derivatives (4),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#7])[#6]",*P(C)(N)=O +202,Phosphorus halogen derivatives (5),"[Pv5X4]([F,Cl,Br,I])([#6])([#6])=[SX1]",*P(C)(C)=S +203,Phosphorus halogen derivatives (6),"[Pv5X4]([#8])([#6])([F,Cl,Br,I])(=[SX1])",*P(C)(O)=S +204,Phosphorus halogen derivatives (7),"[Pv5X4](=[SX1])([F,Cl,Br,I])([#16])[#6]",*P(C)(S)=S +205,Phosphorus V derivatives,[Pv5X4]([!#1])([!#1])([!#1])=[NX2],*P(*)(*)=N +206,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC +207,Thiocyanates,[SX2][CX2]#[NX1],N#CS +208,Sulfonylhalides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +209,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O +210,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +211,Alkylsulfates,"[#6,#1][OX2,OH1][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]",**S(=O)(=O)OC +212,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O +213,All types of 3-valent phosphorus and similar (2),"[Pv3X3]([#8])([#8])[F,Cl,Br,I]",*P(O)O +214,All types of 3-valent phosphorus and similar (3),"[Pv3X3]([#8])([#6])[F,Cl,Br,I]",*P(C)O +215,All types of 3-valent phosphorus and similar (4),"[Pv3X3]([#6])([#6])[F,Cl,Br,I]",*P(C)C +216,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C +217,All types of 3-valent phosphorus and similar (6),"[Pv3X3]([#8])([#7])[F,Cl,Br,I]",*P(N)O +218,All types of 3-valent phosphorus and similar (7),"[Pv3X3]([#7])([#7])[F,Cl,Br,I]",*P(N)N +219,All types of 3-valent phosphorus and similar (8),"[#16][Pv3X3]([#6])[F,Cl,Br,I]",*P(C)S +220,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N +221,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C +222,Hydroxamic acid haloanhydrides,"[CX3]([#6])([F,Cl,Br])=[NX2][#8]",*C(C)=NO +223,Halothioanhydrides,"[#6][CX3](=[SX1])[F,Cl,Br,I]",*C(C)=S +224,Halocarbonates,"[#8][CX3](=[OX1])[F,Cl,Br,I]",*C(O)=O +225,Halocarbamates,"[#7][CX3](=[OX1])[F,Cl,Br,I]",*C(N)=O +226,Isocyanides,"[#6][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +227,Azides,"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +228,Thione esters,"[#6,#1][CX3](=[SX1])[OX2][#6]",*C(=S)OC +229,Acylsulfides,"[#6,#1][CX3](=[OX1])[SX2][#6]",*C(=O)SC +230,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S +231,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S +232,Peroxides,[OX2][OX2],OO +233,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS +234,Nitroso,[#6][NX2]=[OX1],CN=O +235,Nitrates,"[#6][OX2][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*OC +236,N-Nitro,"[#7][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*N +237,N-Nitroso,[#7][NX2]=[OX1],NN=O +238,Azo,[#6][NX2]=[NX2][#6],CN=NC +239,Azoxy,"[#6][$([NX2]=[NX3+]([O-])[#6]),$([NX2]=[NX3](=[OX1])[#6])]",*C +240,Nitroso dimers,"[$([#6][NX3+]([OX1-])=[NX3+]([OX1-])[#6]),$([#6][NX3](=[OX1])=[NX3](=[OX1])[#6])]",* +241,Sulfenyl halides,"[#6][Sv2X2][F,Cl,Br,I]",*SC +242,Sulfinyl halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +243,Diazonium salts,"[$([NX2+]#[NX1]),$([NX2]#N)]",* +244,Cyclic and linear haloamidines,"[CX3](=[#7])([#7])[Cl,Br,I]",*C(N)=N +245,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC +246,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C +247,Hydroxylamines,[OH1][NX3][#6],CN[OH] +248,N-Oxides,"[$([OX1-,OH1][#7X4+]([*])([*])([*])),$([OX1]=[#7X4v5]([*])([*])([*])),$([OX1]=[Nv5X3&!$([Nv5X3](=[OX1])=[OX1])](=[*])([*])),$([OX1-,OH1][#7X3+R](~[R])(~[R])),$([OX1]=[#7v5X3R](~[R])(~[R]))]",* +249,Aminals,N[CX4]N,NCN +250,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C +251,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C +252,α-Haloketones and similar,"[#6][CX3](=[OX1])[CX4][Cl,Br,I]",*CC(C)=O +253,β-Haloamines,"[NX3][CX4][CX4][Cl,Br,I]",*CCN +254,β-Halosulfides,"[Sv2X2][CX4][CX4][Cl,Br,I]",*CCS +255,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O +256,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O +257,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C +258,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O +259,Nitrovinyl,"[CX3]=[CX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +260,Acrylonitriles,[NX1]#CC=C,C=CC#N +261,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O +262,Vinylpyridines and similar,"[$(n1c([CX3]=[CX3])cccc1),$(n1cc([CX3]=[CX3])ccc1),$(n1ccc([CX3]=[CX3])cc1)]",* +263,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1 +264,Ketenes,[CX3]=[CX2]=[OX1],C=C=O +265,Allenes,C=C=C,C=C=C +266,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1 +267,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1 +268,Aziridines,[CX4]1[NX3][CX4]1,C1CN1 +269,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1 +270,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1 +271,Selen in chain,[Sev2X2],[SeH2] +272,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O +273,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N +274,Benzylhalogenides and similar,"c1ccccc1([CX4][Cl,Br,I])",*Cc1ccccc1 +275,Halomethyl ethers,"[F,Cl,Br,I][CX4][#8]",*CO +276,Halomethyl thioethers,"[F,Cl,Br,I][CX4][#16]",*CS +277,Halomethyl amines,"[F,Cl,Br,I][CX4][#7]",*CN +278,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O +279,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S +280,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S +281,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S +282,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S +283,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O +284,Positively charged N-heterocycles,[#7v4X3R],N +285,Organometallic compounds,"[$([Te]~[#6]),$([As]~[#6]),$([Ge]~[#6]),$([Hg]~[#6]),$([Co]~[#6]),$([Fe]~[#6]),$([Mn]~[#6]),$([Cr]~[#6]),$([Ti]~[#6]),$([Sn]~[#6])]",* +286,"Isothiazolinone, isothiazolinthione and their derivatives","[#6]1=,:[#6]C(=[OX1,SX1])N[SX2]1",*=C1C=CSN1 +287,Acyl and thioacyl halides,"[!$(C=C);!$(C#C)]C(=[O,SX1])[F,Cl,Br,I]",*C(*)=* +288,Imidoyl halides,"[!$(C=C);!$(C#C)]C(=N)[F,Cl,Br,I]",*C(*)=N +289,Esters of aromatic alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][a]",**C(*)=* +290,Acid anhydrides and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N]C(=[O,SX1,N])",*C(=*)*C=* +291,Esters of unsaturated alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,S,N])[O,S][$(C=C),$(C=N),$(C#C),$(C#N)]",**C(*)=* +292,"β-Lactones, β-lactams and their thio analogues","[#6]1C(=[O,S])[O,N,S][#6]1",*=C1*CC1 +293,Benzo-fused five-membered heterocycles,"[C,N,O,S,a]c1[n,o,s]c2ccccc2[n,o,s]1",*c1*c2ccccc2*1 +294,(Thio)carbonyl and imine derivatives of five-membered heterocycles,"[#6]1[#6](=[N,O,S])[#7,#8,#16][#6][#7,#8,#16]1",*=C1*C*C1 +295,Phthalic anhydrides and their thio and aza analogues,"[C,O]=[#6]1[#7,#8,#16][#6](=[O,N,SX1])c2ccccc12",*=C1*C(=*)c2ccccc21 +296,Acylating agents,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][CX4,O,S][$(C=O),a,$(C=C),$(C#C),$(C=N),$(C#N)]",***C(*)=* +297,Heteryl-substituted benzenes,"C1=[C,N][$(S(=O)(=O)),$(C=[N,O]),$(S=O)][C,N]=C1c2ccccc2",*1*=CC(c2ccccc2)=*1 +298,Cyclopentanone and cyclopentathione derivatives,"[CH2,CH]=C1C(=[OX1,SX1])**C1",*=C1**CC1=* +299,"Ortho-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])c([OH,NH2,NH,$(N=N),$(N(C)C)])ccc1",*c1ccccc1* +300,"Para-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])ccc([OH,NH2,NH,$(N=N),$(N(C)C)])c1",*c1ccc(*)cc1 +301,"Meta-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])cc([OH,NH2,NH,$(N(C)C)])cc1",*c1cccc(*)c1 +302,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH] +303,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1 +304,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1 +305,Haloethyl-substituted aromatic compounds,"C([F,Cl,Br,I])[CH2,CH][a]",**C* +306,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1 +307,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1 +308,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12 +309,vic-Difluoroalkyl group,"F[CH2,CH]C(F)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(F)*F +310,vic-Dichloroalkyl group,"Cl[CH2,CH]C(Cl)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Cl)*Cl +311,vic-Dibromoalkyl group,"Br[CH2,CH]C(Br)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Br)*Br +312,vic-Diiodoalkyl group,"I[CH2,CH]C(I)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(I)*I +313,Carboxylic acid anhydrides,"[$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6]1),$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6][#6]1)]",* +314,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl +315,Lactones,"[$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6]1),$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6][#6]1)]",* +316,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O +317,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC +318,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC +319,Cyclic sulfonic acid esters,"[$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +320,Cyclic sulfuric acid esters,"[$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +321,Halo acetates,"[F,Cl,Br,I][#6][CX3](=[OX1])[OX2H1]",*CC(=O)[OH] +322,Halo acetamides,"[F,Cl,Br,I][#6][CX3](=[OX1])[NX3]",*CC(N)=O +323,Halo ethers,"[$([F,Cl,Br,I]C[OX2]C),$([F,Cl,Br,I]CC[OX2]C)]",* +324,Haloethyl sulfides (S-mustard),"[F,Cl,Br,I][CX4][CX4][SX2]",*CCS +325,Haloethyl amines (N-mustard),"[F,Cl,Br,I][CH2][CH2][NX3]",*[CH2][CH2]N +326,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O +327,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N +328,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C +329,"α, β-Unsaturated nitro compounds","[#6]=[#6][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +330,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O +331,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C +332,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH] +333,"α, β-Unsaturated carbonyl compounds",[#6]=[#6][CX3](=[OX1])([!#1!$([OH1])]),*C(=O)C=C +334,Alkyl halide,"[*!$([a])&!$(C=C)&!$(C#C)][CX4][F,Cl,Br,I]",*C* +335,Aryl halide,"[a!r0][F,Cl,Br,I]",** +336,Halogenated allylic group,"[F,Cl,Br,I][CX4][CX3]=[CX3]",*CC=C +337,Halogenated benzylic group,"c[CX4][F,Cl,Br,I]",*Cc +338,Diazo compounds,"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +339,Organo metallic compounds,"[$([Cu][#6]),$([Ag][#6]),$([Au][#6]),$([Zn][#6]),$([Cd][#6]),$([Hg][#6]),$([Sn][#6]),$([Pb][#6]),$([As][#6]),$([Sb][#6])]",* +340,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C +341,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C +342,Iodine,II,II +343,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H] +344,Sulfoxides,[Sv4X3](=[OX1]),O=S +345,Sulfenyl iodides,[SX2][IX1],SI +346,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS +347,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S +348,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS +349,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH] +350,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1 +351,(Dithio) carbamates,"[OX2,SX2][CX3](=[OX1,SX1])[NX3]",*C(=*)N +352,Organotin compounds,[Sn][#6],C[Sn] +353,Pyrethroids,"[$(CC(=C[CH]1C([CH]1C(=O)OC1C(=C(C(=O)C1)CC=CC=C)C)(C)C)C),$(C(=C[CH]1C([CH]1C(=O)O[CH]1C(=C(C(=O)C1)CC=CC=C)C)(C)C)(C)C(=O)OC)]",* +354,Organophosphorothionate esters,"[Pv5X4](=[SX1])([OX2][#6])([OX2,SX2][#6])([OX2,SX2][#6])",C*P(=S)(*C)OC +355,Acetates,"[CH,$([C!R](=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R,NX3!R][$([a;r6]),$([a;r5]),$(C=C),$(C#C)]",***=* +356,Acyclic anhydrides,"[CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R][CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])]=[O,SX1]",*=***=* +357,Dialkyl carbamoylhalides,"[NH2!R,$([NH!R](C=O)[#6!R]),$(N(C=O)([#6!R])[#6!R])]C(=O)[F,Cl,Br,I]",*C(*)=O +358,Phosphonic acid halides,"[#6]O[P!R](=O)(O[#6])[F,Cl,Br,I,$(C#N)]",*P(=O)(OC)OC +359,Cyclopropenones,"[#6]1([#1,#6])=,:[#6]([#1,#6])-,:[#6]1=O",*C1=C(*)C1=O +360,β-Lactones,C1C(=O)OC1,O=C1CCO1 +361,Thio-lactones,C1C(=O)SC1,O=C1CCS1 +362,Azlactones,"C1=[O,SX2,NX2,CX3]CC(=[O,SX2])[O,SX2,NX3]1",*=C1*C=*C1 +363,Cyclic anhydrides,"[#6R,#8R,#16X2R][#6R](=[O,SX1])[#8R,#16X2R][#6R]([#6,#8R,#16X2])=[#8,#16X1]",*C(=*)*C(*)=* +364,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC +365,Polarised alkene-aldehydes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][CH]=O",*=*[CH]=O +366,Polarised alkene-ketones,"[$([$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[#6]);!$([#6X3]1=,:[#6X3H][CX3](=[OX1])[#6X3]=,:[#6X3][#6X3]1(=[OX1]));!$([CX3]1(=[OX1])[CX3](=[OX1])[#6X3]=,:[#6X3H][#6X3]=,:[#6X3]1)]",* +367,Polarised alkene-esters,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)O[#6]",*=*C(=O)OC +368,Polarised alkene-amides,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)*=* +369,Polarised alkene-nitros,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",**=* +370,Polarised alkene-cyanos,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C#N",*=*C#N +371,Polarised alkene-alkyl sulphonates,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)O[#6]",*=*S(=O)(=O)OC +372,Polarised alkene-alkyl sulfones,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)[#6]",*=*S(C)(=O)=O +373,Polarised alkene-alkyl sulfinyls,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][SX3](=O)[#6]",*=*S(C)=O +374,Polarised alkene-oximes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C=[NX2][OH]",*=*C=N[OH] +375,Polarised alkene-pyridines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncccc1),$(c1ccncc1)]",**=* +376,Polarised alkene-pyrazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]c1nccnc1",*=*c1cnccn1 +377,Polarised alkene-pyrimidines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncc1),$(c1ncccn1),$(c1cncnc1)]",**=* +378,Polarised akene-triazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1),$(c1nnncc1),$(c1cnnnc1)]",**=* +379,Azocarbonamides,"[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]C(=O)N=NC(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)N=NC(*)=O +380,Allyl alcohols,"[CH2,$([CH](=C)[#6])]=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",*=*[CH2][OH] +381,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH] +382,Polarised alkyne-aldehydes,"[CH,$(C(#C)[#6])]#C[CH]=O",*#C[CH]=O +383,Polarise alkyne-ketones,"[CH,$(C(#C)[#6])]#CC(=O)[#6]",*#CC(C)=O +384,Polarised alkyne-esters,"[CH,$(C(#C)[#6])]#CC(=O)O[#6]",*#CC(=O)OC +385,Polarised alkyne-amides,"[CH,$(C(#C)[#6])]#CC(=O)[$([NH2]),$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)C#* +386,Polarised alkyne-nitros,"[CH,$(C(#C)[#6])]#C[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C#* +387,Polarised alkyne-cyano,"[CH,$(C(#C)[#6])]#CC#N",*#CC#N +388,Polarised alkyne-alkyl sulphonates,"[CH,$(C(#C)[#6])]#CS(=O)(=O)O[#6]",*#CS(=O)(=O)OC +389,Polarised alkyne-alkyl sulfones,"[CH,$(C(#C)[#6])]#CS(=O)(=O)[#6]",*#CS(C)(=O)=O +390,Polarised alkyne-alkyl sulfinyls,"[CH,$(C(#C)[#6])]#C[SX3](=O)[#6]",*#CS(C)=O +391,Polarised alkyne-pyridines,"[CH,$(C(#C)[#6])]#C[$(c1ncccc1),$(c1ccncc1)]",*C#* +392,Polarised alkyne-pyrazines,"[CH,$(C(#C)[#6])]#Cc1nccnc1",*#Cc1cnccn1 +393,Polarised alkyne-pyrimidines,"[CH,$(C(#C)[#6])]#C[$(c1ncccn1),$(c1cncnc1),$(c1ncncc1)]",*C#* +394,Polarised alkyne-triazines,"[CH,$(C(#C)[#6])]#C[$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1)]",*C#* +395,Propargyl alcohols,"[CH,$(C(#C)[#6])]#C[CH2][OH]",*#C[CH2][OH] +396,Benzoquinones,"[$(C1(=O)[#6]=,:[#6]C(=O)[CH]=C1),$(C1(=O)C(=O)[#6]=,:[#6][CH]=C1)]",* +397,Quinone-imines,"[$(C1(=O)[#6]=,:[#6][$(C=[NH]),$(C=N[CX4])][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])]C=[CH][#6]=,:[#6]1)]",* +398,Quinone-diimines,"[$([CH]1=C[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][$(C=[NH]),$(C=N[CX4])]1),$([CH]1=C[$(C=[NH]),$(C=N[CX4])][$(C=[NH]),$(C=N[CX4])][#6]=,:[#6]1)]",* +399,Aminophenols,"[$(c1([OH])c[cH]c([NH2])cc1),$(c1([OH])c([NH2])cc[cH]c1)]",* +400,Benzenediamines,"[$(c1([NH2])c[cH]c([NH2])cc1),$(c1([NH2])c([NH2])cc[cH]c1)]",* +401,Quinone-methides,"[$(C1=CC(=O)[#6]=,:[#6]C1(=[CH][CX4])),$(C1(=[CH][CX4])C(=O)[#6]=,:[#6]C=C1)]",* +402,Pyranones,"[$([cH]1cc(=[O,NH])cc[o,n]1),$([cH]1cc(=[O,NH])[o,n]cc1),$(c1cc(=[O,NH])[o,n][cH]c1)]",* +403,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1 +404,Mono-aldehydes,"[CH2,$([CH](=O)[CX4]),$([CH](=O)c1a(*)caaa1),$([CH](=O)c1a(*)aaa1)]=O",*=O +405,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2] +406,"Di-substituted α,β-unsaturated alkenes (polarized by an aldehyde moiety)","[$(C(=C)([#6])[#6]);!$(C(=C)([#6])C=[CH2,CH])]=C[CH]=O",*=C[CH]=O +407,Di-substituted allyl alcohols,"C([#6])([#6])=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",CC(C)=*[CH2][OH] +408,"1,2-Dicarbonyls","[CH,$(C(=O)(C=O)[CX4]),$(C(=O)(C=O)c1a(*)aaaa1),$(C(=O)(C=O)c1a(*)aaa1)](=O)[CH,$(C(=O)(C=O)[#6]);!$(C(=O)(C=O)C=[CH2,CH]);!$(C(=O)(C=O)C#C)]=O",O=**=O +409,"1,3-Dicarbonyls","[CH,$(C(=O)([CX4]C=O)[CX4]),$(C(=O)([CX4]C=O)c1a(*)aaaa1),$(C(=O)([CX4]C=O)c1a(*)aaa1)](=O)[CX4][CH,$(C(=O)([CX4]C=O)[#6]);!$(C(=O)([CX4]C=O)C=[CH2,CH]);!$(C(=O)([CX4]C=O)C#C)]=O",O=*C*=O +410,Ethylenediamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][NH2]),$([NH]1[CH2][CH2][NH][CH2][CH2]1)]",* +411,Ethanolamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][OH]),$([NH]1[CH2][CH2]O[CH2][CH2]1)]",* +412,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1 +413,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1 +414,Alkyl halides,"[CH3,$([CH2]([F,Cl,Br,I])[#6]),$([CH]([F,Br,Cl,I])([#6])[#6]);!$([CH2,CH]C=O);!$([CH2,CH][CX4][NX3,SX2]);!$([CH2,CH][CX4][F,Cl,Br,I])][F,Cl,Br,I]",** +415,Alkyl diazos,"[CH3,$([CH2](N=N)[#6]),$([CH](N=N)([#6])[#6])][NX2]=[NH,$(N(=N)[#6])]",*N=* +416,Alkyl sulfates,"[#6]OS(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(=O)(=O)OC +417,Alkyl sulphonates,"[#6]S(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(C)(=O)=O +418,Alkyl (thio)phosphates,"[#6][O,SX2]P(=[O,SX1])([O,SX2][#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(*C)*C +419,Alkyl (thio)phosphonates,"[#6][O,SX2]P(=[O,SX1])([#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(C)*C +420,Allyl acetates,"[#6]C(=[O,SX1])[O,SX2][CH2,$([CH]([O,SX2])[#6])][c,CX3,CX2]",***C(=*)C +421,α-Halocarbonyls,"[$([CH]=[O,SX1]),$(C([#6])=[O,SX1])][CH2,$([CH](C=[O,SX1])[#6])][F,Cl,Br,I]",*** +422,α-Haloalkynes,"[CH,$(C(#C)[#6])]#C[$([CH2](C#C)[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH](C#C)([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*C#* +423,α-Halobenzyls,"[c][$([CH2]([c])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH]([a])([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*c +424,Sulfuranes,C1[SX2]C1,C1CS1 +425,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1 +426,Nitrosoureas,"[NX3]C(=O)[$([NH](C=O)[NX2]=O),$(N(C=O)([#6])[NX2]=O)]",*C(N)=O +427,Nitrosoguanidines,"[NX3]C(=[NH])[$([NH](C=[NH])[NX2]=O),$(N(C=[NH])([#6])[NX2]=O)]",*C(N)=N +428,N-Acytoxy-N-acetylphenyls,"[a][NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)* +429,N-Acytoxy-N-alkoxyamides,"[#6]O[NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)OC +430,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O +431,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O +432,Aromatic sulphonic acids,[a][SX4](=O)(=O)[OH],*S(=O)(=O)[OH] +433,Isothiazol-3-ones,"[cH,$(c(c)([sX2])[#6])]1[cH,$(c(c)(c=O)[#6])]c(=O)[nH,$(n(c=O)([sX2])[#6])][sX2]1",O=c1*:*s*1 +434,Isothiazolin-3-ones,"[CH2,$([CH](C)([SX2])[#6])]1[CH2,$([CH](C)(C=O)[#6])]C(=O)[NH,$(N(C=O)([SX2])[#6])][SX2]1",O=C1**S*1 +435,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl +436,Polarized alkenes with a halogen leaving group,"C=[CH][F,Cl,Br,I]",*[CH]=C +437,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C +438,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C +439,Polarized alkenes with an alkyl (thio)phosphonate leaving group,"C=[CH]OP(=[O,SX])(O[#6])[#6]",*=P(C)(OC)O[CH]=C +440,Polarized alkenes with an alkyl (thio)phosphate leaving group,"C=[CH]OP(=[O,SX])(O[#6])O[#6]",*=P(OC)(OC)O[CH]=C +441,Mustards,"[NX3,SX2][CH2,$([CH]([NX3,SX2])([CX4])[CX4])][CH2,$([CH]([CX4])([Cl,Br,I])[CX4])][Cl,Br,I]",**** +442,"1,2-Dihaloalkanes","[Cl,Br,I][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][Cl,Br,I]",**** +443,Activated pentafluorobenzenes,"c1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-]),$([CH]=O),$(C#N),$(C(=O)[CH3])])c(F)c(F)c(F)c(F)c1(F)",*c1c(F)c(F)c(F)c(F)c1F +444,Formaldehyde releasers (1),"[$(O1COCC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C1),$([OX2H1]CC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C[OX2H1])]",* +445,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH] +446,Formaldehyde releasers (3),"C1(=[OX1])[NX3H1]C(=[OX1])[NX3H1][CX4]1(C[OH1])[NX3H1][CX3](=[OX1])[NX3!H0][#1,#6]",*NC(=O)[NH]C1(C[OH])[NH]C(=O)[NH]C1=O +447,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH] +448,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1 +449,"Hydrazine, hydrazides","[#6,#1][NX3H1][NX3H1][#6,#1]",*[NH][NH]* +450,Nitrobenzenes,"a[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",** +451,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21 +452,Benzylamines,"[#1,CX4!R][NX3]([#1,CX4!R])[CH2]c1ccccc1",*N(*)[CH2]c1ccccc1 +453,Propargyl amines,"[#1,CX4,$(c1ccccc1)][CX2]#[CX2][NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*C#CN(*)* +454,Cyclopropyl amines,"[CX4]1[CX4][CX4]1[NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*N(*)C1CC1 +455,"N-Substituted-4-aryl-1,2,3,6-tetrahydropyridines","[NX3]1([CX4!R])[CX4][CX3]=[CX3](c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2=CCN(C)CC2)c(*)c1* +456,N-Substituted-4-arylpiperidin-4-ol,"[NX3]1([CX4!R])[CX4][CX4][CX4]([OH1])(c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2([OH])CCN(C)CC2)c(*)c1* +457,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O +458,Hydantoins (glycolylurea),"[NX3H1]1[CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NX3H1][CX3]1(=[OX1])",*C1(*)[NH]C(=O)[NH]C1=O +459,Thioureas,"[#1,#6][NX3]([#1,#6])[CX3](=[SX1])[#7]",*N(*)C(N)=S +460,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O +461,Ortho- or parahydroquinones,"[$(c1([OH1])c([OH1])cccc1),$(c1([OH1])ccc([OH1])cc1)]",* +462,Ortho- or paraquinones,"[$([#6]1(=[OX1])-,:[#6]=,:[#6]-,:[#6](=[OX1])-,:[#6]=,:[#6]1),$([#6]1(=[OX1])-,:[#6](=[OX1])-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)]",* +463,Ortho- or paraalkylphenols,"[$(c1([OH1])c([CX4]([#1,#6])[#1,#6])cccc1),$(c1([OH1])ccc([CX4]([#1,#6])[#1,#6])cc1)]",* +464,Quinone methide,"[$([OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]-,:[#6X3]1=[CX3]([#1,#6])[#1,#6]),$([OX1]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[CX3]([#1,#6])[#1,#6])-,:[#6]=,:[#6]1)]",* +465,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1 +466,3-Methylene indoles,"c1ccc([nX3]2([#1,#6]))c(c([CH2][#1,#6])c2)c1",*[CH2]c1cn(*)c2ccccc12 +467,Furans,c1ccc[oX2]1,c1ccoc1 +468,Thiophenes,c1ccc[sX2]1,c1ccsc1 +469,Thiazoles and 2-amino derivatives,"[$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([#1,CX4!R])[sX2]1),$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([NX3]([#1,CX4!R])[#1,CX4!R])[sX2]1)]",* +470,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O +471,2- or 4-Halopyridines,"[$(n1c([Cl,Br,I,F])cccc1),$(n1cccc([Cl,Br,I,F])cc1)]",* +472,Alkynes,"[#6][CX2]#[CX2][#1,#6]",*C#CC +473,Alkylhalides,"[$([CX4]([F,Cl,Br,I])([H,!F!Cl!Br!I])([H,!F!Cl!Br!I])[H,!F!Cl!Br!I]),$([CX4]([#6])([F,Cl,Br,I])([F,Cl,Br,I])[H,!F!Cl!Br!I])]",* +474,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH] +475,Fluoroethyl ethers and amines,"[$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][OX2][#1,#6]),$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][NX3][#6])]",* +476,Three-membered heterocycles,"[#6]1~[#6][#7,#8,#16]1",*1C~C1 +477,Thioles,[Sv2X2H1],[SH] +478,Chlor(brom)anhydrides,"[CX3](=[OX1])[Cl,Br]",*C=O +479,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O +480,Trihalogensubstituted ketones,"[CX3](=[OX1])[CX4]([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C=O +481,Monohalogen substituted ketones,"[CX3](=[OX1])C[Cl,Br,I]",*CC=O +482,Sulphonhalogenanhydrides,"S(=[OX1])(=[OX1])[F,Cl,Br,I]",*S(=O)=O +483,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH] +484,Phosphorus,P,P +485,Selen,[Se],[SeH2] +486,Bor,B,B +487,Silicium,[Si],[SiH4] +488,"Isocyanates, isothiocyanates","[NX2]=[CX2]=[OX1,SX1]",*=C=N +489,Thione,[CX3]=[SX1!R],C=S +490,β-halogen substituted carbonyls,"[CX3](=[OX1])CC[F,Cl,Br,I]",*CCC=O +491,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH] +492,gem-Dihalo propane and cyclopropane,"CC([Cl,Br,I])([Cl,Br,I])C",*C(*)(C)C +493,Activated halides (o-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cc[F,Cl,Br]",*cc* +494,Activated halides (p-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cccc[F,Cl,Br]",*cccc* +495,Activated halides (α-halogen substituted N-heterocycles),"nc[F,Cl,Br]",*cn +496,Activated halides (γ-halogen substituted N-heterocycles),"nccc[F,Cl,Br]",*cccn +497,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S +498,Barbiturates,"N1C(=[OX1,SX1])NC(=[OX1,SX1])C(=C)C1(=[OX1,SX1])",*=C1NC(=*)C(=C)C(=*)N1 +499,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2] +500,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O +501,Crown ethers,[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C,*C~C*C~C*C~C*C~C*C~C*C~C +502,Coumarins (1),"c1cccc2c1oc(=O)c([$(C=[OX1]),$(C=[SX1]),$(S=[OX1]),$(C#[NX1]),F,Cl,Br,I,$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]));!$([CX3](=[OX1])[OH1])])[c!H0]2",*c1cc2ccccc2oc1=O +503,Coumarins (2),"[cH1]1[cH1]c2c3[cH1][cH1]c(cc3oc(=O)c2[cH1]c1[OX2][$([CH2]),$([CH3])])[OX2][C!H0]",*Oc1[cH][cH]c2c([cH]1)c(=O)oc1cc(OC)[cH][cH]c12 +504,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1 +505,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1 +506,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1 +507,Coumarins (6),"c1([F,Cl,Br,I])cc([F,Cl,Br,I])cc2c1oc(=[NX2H1])c([CX3](=[OX1])[NH2])[c!H0]2",*c1cc(*)c2oc(=N)c(C([NH2])=O)cc2c1 +508,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1 +509,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1 +510,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O +511,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N +512,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O +513,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N +514,o-Quinones (3),"CC(=[OX1])C(=[OX1])[#6,#7]",*C(=O)C(C)=O +515,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S +516,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12 +517,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O +518,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH] +519,N-N Single bound not in a ring,[N!R][N!R],NN +520,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC +521,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O +522,Acyl and sulfinyl cyanide,"[$(C(=[OX1])[CX2]#[NX1]),$(S(=[OX1])[CX2]#[NX1])]",* +523,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1 +524,Hydrazine and other nucleophilic NH2-groups,"[NX3H2][#7,#8]",*[NH2] +525,Activated halo- and sulfonyl-aromatics,"c1([F,Cl,Br,I,$(C(C)=NO),$([CX2]#[NX1]),$([CX3]=[OX1]),$([CX4](F)(F)F),$([SX4](=[OX1])=[OX1]);!$([CX3](=[OX1])[OH1])])na([F,Cl,Br,I,$([SX4](=[OX1])(=[OX1])C)])a([!#7])a([!#7])a1",**1:*c(*)n*(*):*:1* +526,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O +527,Acyclic gem-dihalosubstituted carbon atom,"[C!R]([Cl,Br,I])[Cl,Br,I]",*C* +528,Imines,"[N!R]=[C,N]",*=N +529,Michael acceptors (carbonyl containing acrylonitrile derivatives),C[CX3H1]=[CX3!R](C(=[OX1])[!#1]~[!#1])[CX2]#[NX1],*~*C(=O)C(C#N)=[CH]C +530,Over halogenated rings,"a1c([F,Cl,Br,I])c([F,Cl,Br,I])ac([F,Cl,Br,I])a1",*c1*:*c(*)c(*)*1 +531,o-Quinones (1),"[CX3]1(=[!#1!#6])[CX3](=[!#1!#6])[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1",*=C1C=CC=CC1=* +532,o-Quinones (2),CC(=[!#1!#6;!R])C(=[!#1!#6;!R])C,*=C(C)C(=*)C +533,o-Quinones (4),CC(=[!#1!#6;!R])S(=[OX1])(=[OX1]),*=C(C)S(=O)=O +534,p-Quinones (1),"[#6X3]1=,:[#6X3][CX3](=[!#1!#6])[#6X3]=,:[#6X3][#6X3]1(=[!#1!#6])",*=C1C=CC(=*)C=C1 +535,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3 +536,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3 +537,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1 +538,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23 +539,Acid anhydrides and analogues,[!#1](=O)O[!#1]=O,O=*O*=O +540,Acyl halides and analogues,"[C,S](=[O,S])[F,Br,Cl,I]",**=* +541,Cyano carbonyl compounds ,N#CC(=O),N#CC=O +542,Methylendiamines (1),"[!$([C,S]=O)]N([!$([C,S]=O)])[CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*N(*)CN(*)* +543,Methylendiamines (2),"[!$([C,S]=O)][NH][CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*[NH]CN(*)* +544,Methylendiamines (3),"[!$([C,S]=O)][NH][CX4][NH][!$([C,S]=O)]",*[NH]C[NH]* +545,N-Acetoxy amines and their thio analogues,"[#7][#8][C,S]=O",NO*=O +546,α-Halogen substituted N-heterocycles,"[F,Br,Cl,I]-cn",*cn +547,Activated haloaromatics,"[F,Cl,Br,I][$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",** +548,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N +549,Benzyl ammoniums,cC[NX4+],cC[N+] +550,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O +551,Cations,"[#6+,#17+,#53+,#15+,#16+]",* +552,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N +553,Halogen-bonded heteroatoms,"[!#1&!#6][F,Cl,Br,I]",** +554,Cumulated double bonds,"[C,N]=C=[C,O,N,S]",*=C=* +555,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O +556,Singel acyclic N-N bonds,[#7]!@-N,N~N +557,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N +558,Activated double bonds (2),[!c][C!H0]=CC=O,*C=CC=O +559,Activated double bonds (3),"[C!H0]=C[S,N]=O",C=C*=O +560,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O +561,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS +562,Acetoxy group attached to the substituted aromatic ring,"C(=O)O[$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",*OC=O +563,"Oxetanes, thietanes","C1[O,S]CC1",*1CCC1 +564,Trihalomethyl ketones,"CC(=O)C([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C(C)=O +565,Phosphonates,[#6]P(=O)O[#6],COP(C)=O +566,Phosphorus containing compounds ,"NP(=[N,O,S])",*=PN +567,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +568,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O +569,"C, N, O, P and S atoms in unusual valence states","[#6!v4+0,#7!v3+0,#8!v2+0,#15!v3!v5+0,#16!v2!v4!v6+0]",* +570,Sulfurous acid esters,[!#1]OS(=O)O,*OS(O)=O +571,Heteroatom-bonded thiocarbonyls,"C(=S)[O,S,N]",*C=S +572,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS +573,Thiocarbonyls,C(=S)[!#1!H0],*C=S +574,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O +575,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F +576,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O +577,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1 +578,Double acyclic N=N and N=S bonds,"[NR0,SR0]=[NR0]",*=N +579,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1 +580,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC +581,"Iodosos, chlorosos","[Cl,I]=O",*=O +582,Acid grops,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +583,Phosphocyanates,PC#N,N#CP +584,α-Hydroxy nitriles,N#CC[OH],N#CC[OH] +585,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O +586,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO +587,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N +588,Nitrites,[!#1]ON=O,*ON=O +589,Nitroso compounds,[NX2]=O,N=O +590,"Any atoms except organogens, halogens, P, S, K, Na, Mg, Ca",[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +591,Double P=S and P=C bonds,"P=[S,#6]",*=P +592,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F +593,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +594,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1 +595,Phosphorus derivatives,[P!v5],P +596,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C +597,Carboxylic acid esters,[CX4]C(=O)O[#6][!#1],*COC(C)=O +598,"N,N-Dialkyl aniline derivatives (1)","[CX4][NX3]([CX4])c1cc([$([CX4]),$(O[CX4][CX4])])c([#7])[cH]c1",*c1cc(N(C)C)c[cH]c1N +599,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1 +600,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1 +601,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1 +602,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1 +603,"N,N-Dialkyl aniline derivatives (4)","[CX4]N([CX4])c1ccc([CX4][$([OH]),$(C=[C!H0]),$(N[CX4])])cc1",*Cc1ccc(N(C)C)cc1 +604,"N,N-Dialkyl aniline derivatives (5)","[CX4]N([C!H0])c1[cH][cH]c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH][cH]1 +605,"N,N-Dialkyl aniline derivatives (6)","[CX4]N([C!H0])c1[cH]c([CX4])c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH]c1C +606,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O +607,Five-membered heterocycles (1),"C1(=C)C(=O)[#7,#8,#15,#16]N=C1",C=C1C=N*C1=O +608,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O +609,Six-membered heterocycles,"[#7,#8,#15,#16]~C1~[#7,#8,#15,#16]~C[#7,#8,#15,#16][CX3](=[#7,#8,#15,#16])[CX3]1(=[C!H0])",*~C1C(=C)C(=*)*C~*~1 +610,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1 +611,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC +612,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH] +613,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1 +614,"1,2-Diimines, 1,2-diketones and their thio- and phospho-analogues","[#6][#6](=[#7,#8,#15,#16])[#6](=[#7,#8,#15,#16])[#6,Sv6]",*C(=*)C(=*)C +615,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21 +616,NH-Indoles,"[nH]1c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1[nH]c2ccc[cH]c2c1C +617,N-Alkyl substituted indoles,"n1([CH2])c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1c(C)c2[cH]cccc2n1[CH2] +618,Macrocycles,"[*r10,*r11,*r12,*r13,*r14,*r15,*r16,*r17,*r18,*r19,*r20,*r21,*r22,*r23,*r24,*r25,*r26,*r27,*r28,*r29,*r30]",* +619,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH] +620,N-Allophanoylamides and their thio analogues,"NC(=[O,S])NC(=[O,S])NC=[O,S]",*=CNC(=*)NC(=*)N +621,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1 +622,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21 +623,N-Phenylpyrrole derivatives,N1(c2[!#1]cccc2)C([CX4])=C[C!H0]=C1[CX4],CC1=CC=C(C)N1c1cccc*1 +624,"Quinones, quinone-(di)imines and their thio- and phospho-analogues","[#7,#8,#15,#16]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[#7,#8,#15,#16])-,:[#6]=,:[#6]1",*=C1C=CC(=*)C=C1 +625,Five-membered heterocycles (2),"[#7]=C1S[CH]=C([$([CH2]),$(c:c)])N1",*C1=[CH]SC(=N)N1 +626,Five-membered heterocycles (3),"[#7]=C1SC([$([CH2]),$(C=O)])=C([$([CH2]),$(c:c)])N1",*C1=C(*)SC(=N)N1 +627,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c +628,Acethylenes,"[CH2,CH3]C#C[CH2,CH3]",*C#C* +629,α-Halonitriles,"[F,Cl,Br,I][CX4][CX2]#[NX1]",*CC#N +630,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N +631,Benzthiozolium like compounds,"[#7,#8,#16]1-,:[#6]=,:[#6]-,:[#7+]2=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6]21",*1C=C[N+]2=**=**=C12 +632,Cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +633,Di-carbonyls,"[#1,#6][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(*)=O +634,Haloalkyl,"[C!H0]([#1,#6,#7,#8,#16])[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])[Cl,Br,I]",*CC(*)(*)* +635,"Haloalkyl group attached to S, N or O atoms","[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])([Cl,Br,I])[#7,#8,#16]",*C(*)(*)* +636,Haloethylenes,"[CX3!H0]=[CX3]([#1,Cl,Br,I])[Cl,Br,I]",*C(*)=C +637,Halopyridines,"c1([F,Cl,Br,I])n[c,n][c,n][c,n][c,n]1",*c1*:*:*:*n1 +638,Heptanes,"[CH3][CH2][CH2][CH2][CH2][CH2][CH2,CH3]",*[CH2][CH2][CH2][CH2][CH2][CH3] +639,N-Oxides (six-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1)]",* +640,N-Oxides (five-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1)]",* +641,Phosphorus cations,[#15+],[PH4+] +642,Peroxide like compounds,"O[F,Cl,Br,I]",*O +643,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O +644,Double P=O bonds,[#15]=O,O=P +645,Pyridinium like compounds,"[#6][#7+]1=,:[#6]-,:[#6,#7]=,:[#6]-,:[#6,#7]=,:[#6]1",C[N+]1=C*=C*=C1 +646,Quinolizinium like compounds,"[#6,#7]1=,:[#6,#7]-,:[#6,#7]=,:[#7+]2-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6]2=,:[#6,#7]1",*1=**=[N+]2*=**=*C2=*1 +647,Sulfates,"[Sv6X4](=[OX1])(=[OX1])([#8])[#6,#8]",*S(O)(=O)=O +648,Thio aldehydes,"[#6,#1][CX3]([H])=[SX1]",*C([H])=S +649,Thio halogens,"[#16][F,Cl,Br,I]",*S +650,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH] +651,Thiozolium like compounds,"[#6][#7+]1=,:[#6]-,:[#7,#8,#16]-,:[#6]=,:[#6]1",C[N+]1=C*C=C1 +652,Acyl Halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +653,Sulphonyl Halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +654,Alkyl Halides,"[CX4][F,Cl,Br,I]",*C +655,Activated Halides,"[$(c([F,Cl,Br,I])c[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])aac[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])n),$(c([F,Cl,Br,I])aan)]",* +656,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +657,Aldehydes (including aminoformyl moieties),"[$([#1,#6][CX3]([H])=[OX1]),$([#7]([#1,#6])([#1,#6])[CX3H1]=[OX1])]",* +658,Nitrosos,[NX2]=[OX1],N=O +659,Picrates,"c1([OH1,O-])c([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])",*c1cc(*)c(*)c(*)c1 +660,Perchlorates (periodates),"[$([Clv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-]),$([Iv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-])]",* +661,Simple anilines and phenols,"[$(c1([NX3]([#1,#6])[#1,#6])ccccc1),$(c1([OH1])ccccc1)]",* +662,Vinyl ketones (Michael acceptors),[CX3]([!R])([!R])=[CX3][CX3](=[OX1])[!$([OH1])!$([OX2][CH2])!$([NH2])!$([CX2]#[NX1])!a],*C(=O)C=C(*)* +663,Metals,[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +664,Non-organic chemistry atoms,[!#6!#1!#7!#8!#9!#17!#35!#53!#15!#14!#16],* +665,Atoms not supported in ALOGPS program,[!#1!#6!#7!#8!#16!#15!#9!#17!#35!#53],* +666,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F +667,Carbonyl compouns: aldehydes or ketones,"[$([H][CX3]([#1,#6])=[OX1]),$([#6&!$(C#N)][CX3](=[OX1])[#6&!$(C#N)])]",* +668,Thiocarbonyl compounds: thioaldehydes or thioketones,"[$([#1,#6][#6X3](=[SX1])[#1,#6]),$([#6]=[CX2]=[Sv2X1])]",* +669,Thioaldehydes,"[#1][CX3]([#1,#6])=[SX1]",*C([H])=S +670,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S +671,Hydrazones,"[CX3]([#1,#6])([#1,#6])=[NX2][#7X3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)* +672,Semicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=O)N(*)* +673,Thiosemicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=S)N(*)* +674,Oximes,"[#1,#6][CX3]([#1,#6])=[NX2][OH1]",*C(*)=N[OH] +675,Oxime ethers,"[#1,#6][CX3]([#1,#6])=[NX2][OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NOC +676,Ketene acetal derivatives,"[#1,#6][CX3]([#1,#6])=[CX3]([!#6!#1])[!#6!#1]",*C(*)=C(*)* +677,Carbonyl hydrates,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OH1]",[OH]*[OH] +678,Hemiacetals / Hemiketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*[OH] +679,Acetals / Ketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*OC +680,Hemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,*])[#1,*]",*O*N(*)* +681,Thiohemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[NX3]([#1,*])[#1,*]",*S*N(*)* +682,Thioacetals / Thioketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[SX2,OX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)]",C**SC +683,Enols,"[CX3]([#1,#6])([#1,#6])=[CX3]([OH1])[#1,#6]",*C(*)=C(*)[OH] +684,Enolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([OX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]",*C(*)=C(*)OC +685,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH] +686,Alcohols,"[$([CX4][OH1])&!$(C([OH1])[#7,#8,#15,#16,F,Cl,Br,I])]",* +687,Primary alcohols,"[$([#6][CH2][OH1]),$([CH3][OH1])]",* +688,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH] +689,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH] +690,"1,2-Diols","[CX4]([OH1])([#1,#6])([#1,#6])[CX4]([OH1])([#1,#6])([#1,#6])",*C(*)([OH])C(*)(*)[OH] +691,"1,2-Aminoalcohols","[CX4]([#1,#6])([#1,#6])([OH1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([CX4][CX4][OH1])[#6&!$([CX3]=[OX1,SX1,NX2,C])])]",*C(*)(*)C(*)(*)[OH] +692,Phenols,c[OH1],c[OH] +693,Diphenols,"[$(c([OH1])c([OH1])),$(c([OH1])[aR1]c([OH1])),$(c1([OH1])aac([OH1])aa1)]",* +694,Enediols,"[CX3]([#1,#6])([OH1])=[CX3]([#1,#6])([OH1])",*C([OH])=C(*)[OH] +695,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC +696,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc +697,Diarylethers,c[OX2&!$([OX2r3])]c,cOc +698,Hydroperoxides,"[#1,#6][OX2][OX2H1]",*O[OH] +699,Hydrazine derivatives,"[$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])][$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])]",** +700,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +701,Primary aromatic amines,[NX3H2]c,c[NH2] +702,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C +703,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C +704,Secondary aromatic amines,[NX3H1](c)c,c[NH]c +705,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C +706,Tertiary mixed amines (aryl alkyl),"c[NX3]([CX4&!$([CX4]([NX3])[O,N,S,P])])[c,CX4&!$([CX4]([NX3]c)[O,S,N,P])]",*N(c)C +707,Quaternary ammonium salts,"[NX4,NX4+]([#6])([#6])([#6])[#6]",C*(C)(C)C +708,"Halogen derivatives (alkyl, alkenyl, aryl)","[CX4,CX3,c;!$([#6]=[OX1])][F,Cl,Br,I]",** +709,Aryl fluorides,aF,*F +710,Aryl chlorides,aCl,*Cl +711,Aryl bromides,aBr,*Br +712,Aryl iodides,aI,*I +713,Organolithium compounds,[Li][#6],[Li]C +714,Organomagnesium compounds,[Mg][#6],C[Mg] +715,Carboxylic acid derivatives,"[#1,#6][CX3](=[OX1])[!#1!#6!$([SH1,SX2])]",*C(*)=O +716,Carboxylic acid salts,"[#1,#6][CX3](=[OX1])[OX1-]",*C(=O)[O-] +717,Carboxylic acid amides,"[#1,#6][CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=O)N(*)* +718,Carboxylic acid primary amides,"[#1,#6][CX3](=[OX1])[NX3H2]",*C([NH2])=O +719,Carboxylic acid secondary amides,"[#1,#6][CX3](=[OX1])[NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)[NH]C +720,Carboxylic acid tertiary amides,"[#1,#6][CX3](=[OX1])[NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)N(C)C +721,Lactams,"[#6R][CX3R](=[OX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=O +722,Carboxylic acid hydrazides,"[$([#6,#1][#6X3](=[OX1])[#7X3&!$([#7X3]([*]=[OX1,SX1])[#7X3]([*]=[OX1,SX1]))][#7X3]),$(C1(=O)[NX3][NX3]C(=O)cc1)]",* +723,Carboxylic acid azides,"[#1,#6][CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C(*)=O +724,Hydroxamic acids,"[#1,#6][CX3](=[OX1])[NX3][OH1]",*C(=O)N[OH] +725,Carboxylic acid amidines,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,N])]",*N=C(*)N(*)* +726,Carboxylic acid amidrazones,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)N(*)N(*)* +727,Nitriles,"[#1,#6&!$([CX3]=[OX1,SX1])][CX2]#[NX1]",*C#N +728,Acyl fluorides,"[#1,#6][CX3](=[OX1])F",*C(=O)F +729,Acyl chlorides,"[#1,#6][CX3](=[OX1])Cl",*C(=O)Cl +730,Acyl bromides,"[#1,#6][CX3](=[OX1])Br",*C(=O)Br +731,Acyl iodides,"[#1,#6][CX3](=[OX1])I",*C(=O)I +732,Acyl cyanides,"[#1,#6][CX3](=[OX1])[CX2]#[NX1]",*C(=O)C#N +733,Imido esters,"[#1,#6][CX3](=[NX2][#1,#6])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*N=C(*)OC +734,Thiocarboxylic acid derivatives,"[$([#1,#6][CX3](=[SX1])[!#1!#6]),$([#1,#6][CX3](=[OX1])[SX2])]",* +735,Thiocarboxylic acids,"[$([#1,#6][CX3](=[SX1])[OH1,SH1]),$([#1,#6][CX3](=[OX1])[SH1])]",* +736,Thiocarboxylic acid esters,"[$([#1,#6][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#1,#6][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +737,Thiolactones,"[$([#6R][CX3R](=[SX1])[OX2R,SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])]),$([#6R][CX3R](=[OX1])[SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])])]",* +738,Thiocarboxylic acid amides,"[#1,#6][CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=S)N(*)* +739,Thiolactams,"[#6R][CX3R](=[SX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=S +740,Imidothioesters,"[#1,#6][CX3](=[NX2][#1,#6])[SX2][C&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)SC +741,Oxohetarenes,"[$(c(=[OX1])[$(n[#1,#6]),o,s]),$(c(=[OX1])a[$(n[#1,#6]),o,s]),$(c(=[OX1])aa[$(n[#1,#6]),o,s]),$(c(=[OX1])aaa[$(n[#1,#6]),o,s])]",* +742,Thioxohetarenes,"[$(c(=[SX1])[$(n[#1,#6]),o,s]),$(c(=[SX1])a[$(n[#1,#6]),o,s]),$(c(=[SX1])aa[$(n[#1,#6]),o,s]),$(c(=[SX1])aaa[$(n[#1,#6]),o,s])]",* +743,Iminohetarenes,"[$(c(=N)[$(n[#1,#6]),o,s]),$(c(=N)a[$(n[#1,#6]),o,s]),$(c(=N)aa[$(n[#1,#6]),o,s]),$(c(=N)aaa[$(n[#1,#6]),o,s])]",* +744,Orthocarboxylic acid derivatives,"[CX4&!$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]))]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])([!#1!#6])([!#1!#6])[!#1!#6]",*C(*)(*)* +745,Carboxylic acid orthoesters,"[#1,#6][CX4]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*C(OC)(OC)OC +746,Carboxylic acid amide acetals,"[CH1,$([CX4][#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[NX3]([#1,*])[#1,*]",*N(*)*(OC)OC +747,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O +748,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O +749,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O +750,CO2 derivative (general),"[$([Cv4X4]([!#1!#6])([!#1!#6])([!#1!#6])[!#1!#6]),$([CX3](=[!#1!#6])([!#1!#6])[!#1!#6]),$([CX2](=[!#1!#6])=[!#1!#6]),$([CX2](#[!#1!#6])[!#1!#6])]",* +751,Carbonic acid derivatives,"[$([CX3](=[OX1])([!#1!#6])[!#1!#6])&!$([CX3](=[OX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +752,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH] +753,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC +754,Carbonic acid ester halides,"[#6][OX2][CX3](=[OX1])[F,Cl,Br,I]",*C(=O)OC +755,Thiocarbonic acid derivatives,"[$([CX3](=[SX1])([!#1!#6])[!#1!#6])&!$([CX3](=[SX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5]),$([CX3](=[OX1])([!#1!#6])[SX2])&!$([CX3](=[OX1])([#7,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +756,Thiocarbonic acid monoesters,"[$([OH1,SH1][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([OH1][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([SH1][CX3](=[SX1,OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +757,Thiocarbonic acid diesters,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +758,Thiocarbonic acid ester halides,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[F,Cl,Br,I]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[F,Cl,Br,I])]",* +759,Carbamic acid derivatives,"[NX3]([#1,*])([#1,*])[CX3](=[OX1])[!#1!#6!#16!$([Pv5])]",*C(=O)N(*)* +760,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH] +761,Carbamic acid esters (urethanes),"[#6][OX2][CX3](=[OX1])[NH2,NH1,NX3]",*C(=O)OC +762,Carbamic acid halides,"[F,Cl,Br,I][CX3](=[OX1])[NX3]",*C(N)=O +763,Thiocarbamic acid derivatives,"[$([NX3&!$([NX3]([CX3]=[SX1])[CX3]=[OX1,SX1,NX2])][CX3](=[SX1])[!#1!#6!#7!$([Pv5])]),$([NX3&!$([NX3]([CX3]=[OX1])[CX3]=[OX1,SX1,NX2])][CX3](=[OX1])[SH1,SX2])]",* +764,Thiocarbamic acids,"[$([OH1,SH1][CX3](=[SX1])[NX3]),$([SH1][CX3](=[OX1])[NX3])]",* +765,Thiocarbamic acid esters,"[$([#6][OX2,SX2][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])]),$([#6][SX2][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])])]",* +766,Thiocarbamic acid halides,"[F,Cl,Br,I][CX3](=[SX1])[NX3]",*C(N)=S +767,Isoureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([OX2])=[NX2][#1,#6]",*N=C(O)N(*)* +768,Isothioureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([S&!$([SX2]([CX3]=N)C=C)])=[NX2][#1,#6]",*N=C(S)N(*)* +769,Guanidines,"N[CX3](=[NX2][#1,#6])N",*N=C(N)N +770,Semicarbazides,"[$([NX3][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[OX1])[NX3]N=C)]",* +771,Thiosemicarbazides,"[$([NX3][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[SX1])[NX3]N=C)]",* +772,Isonitriles,"[#6&!$([CX3]=[OX1,SX1])][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +773,Sulfuric acid derivatives,[!#1!#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(*)(=O)=O +774,Sulfuric acid,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])[OX2,O-]",*S(*)(=O)=O +775,Sulfuric acid monoesters,"[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(=O)(=O)OC +776,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC +777,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O +778,Sulfuric acid amides,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])N",*S(N)(=O)=O +779,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O +780,Sulfuryl halides,"[!#1!#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +781,Sulfonic acid derivatives,[#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(C)(=O)=O +782,Sulfonic acids,"[#6][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(C)(=O)=O +783,Sulfonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +784,Sulfones,"[#6][Sv6X4](=[OX1,SX1,NX2])(=[OX1,SX1,NX2])[#6]",*=S(=*)(C)C +785,Sulfinic acid derivatives,[#6][Sv4X3](=[OX1])[!#1!#6],*S(C)=O +786,Sulfinic acids,"[#6][Sv4X3](=[OX1])[OH1,O-]",*S(C)=O +787,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O +788,Sulfinic acid halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +789,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O +790,Sulfenic acid derivatives,[#6][Sv2X2][!#6!#1!S],*SC +791,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH] +792,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC +793,Sulfenic acid halides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][F,Cl,Br,I]",*SC +794,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C +795,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH] +796,Thiophenols,c[Sv2H1],c[SH] +797,Phosphoric acid derivatives,"[OX1]=[Pv5X4]([H,!#6!$([SX2])])([H,!#6!$([SX2])])[H,!#6!$([SX2])]",*P(*)(*)=O +798,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH] +799,Phosphoric acid esters,[OX1]=[Pv5X4]([OX2][#6])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(=O)OC +800,Phosphoric acid halides,"[OX1]=[Pv5X4]([F,Cl,Br,I])([!#6!$([SX2])])[!#6!$([SX2])]",*P(*)(*)=O +801,Phosphoric acid amides,[OX1]=[Pv5X4]([NX3])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(N)=O +802,Thiophosphoric acid derivatives,"[$([SX1]=[Pv5X4]([H,!#6])([H,!#6])[H,!#6]),$([OX1]=[Pv5X4]([SX2])([H,!#6])[H,!#6])]",* +803,Thiophosphoric acids,"[$([SX1]=[Pv5X4]([OH1,SH1])([O,S])[O,S]),$([OX1]=[Pv5X4]([SH1])([O,S])[O,S])]",* +804,Thiophosphoric acid esters,"[$([SX1]=[Pv5X4]([OX2,SX2][#6])([!#6])[!#6]),$([OX1]=[Pv5X4]([SX2][#6])([!#6])[!#6])]",* +805,Thiophosphoric acid halides,"[$([SX1]=[Pv5X4]([F,Cl,Br,I])([!#6])[!#6]),$([OX1]=[Pv5X4]([F,Cl,Br,I])([SX2,SH1])[!#6])]",* +806,Thiophosphoric acid amides,"[$([SX1]=[Pv5X4]([NX3])([!#6])[!#6]),$([OX1]=[Pv5X4]([NX3])([SX2,SH1])[!#6])]",* +807,Phosphonic acid derivatives,[OX1]=[Pv5X4]([#6])([!#6])[!#6],*P(*)(C)=O +808,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH] +809,Phosphonic acid esters,[OX1]=[Pv5X4]([#6])([OX2][#6])[!#6],*P(C)(=O)OC +810,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C +811,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O +812,Boronic acid derivatives,[Bv3X3]([#6])([!#6])[!#6],*B(*)C +813,Boronic acids,"[BX3]([#6])([OH1,SH1])[O,S]",*B(*)C +814,Boronic acid esters,"[BX3]([#6])([OX2][#6])[H,!#6]",*B(C)OC +815,Aromatic compounds,[a!r0],* +816,Heterocyclic compounds,[*R]~[*R&!#6]~[*R],*~*~* +817,Aromatic heterocyclic compounds,[a!#6!r0],* +818,α-Aminoacids,"[OH1][CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([#6])[#6])&!$([NH1](CC(=O)[OH1])[CX3]=[OX1,SX1])]",*C(*)(*)C(=O)[OH] +819,α-Hydroxyacids,"[OH1][CX3](=[OX1])[CX4]([OH1])[#1,#6]",*C([OH])C(=O)[OH] +820,"1,2-Diamines","[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])[CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CCN(*)* +821,"1,2-Dithiols","[CX4]([SH1])([#1,#6])([#1,#6])[CX4]([SH1])([#1,#6])([#1,#6])",*C(*)([SH])C(*)(*)[SH] +822,"1,2-Aminothiols","[SH1][CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CC[SH] +823,α-Oxoacids,"[OH1][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(=O)[OH] +824,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH] +825,Dithiophenols,"[$(c([SH1])c([SH1])),$(c([SH1])[aR1]c([SH1])),$(c1([SH1])aac([SH1])aa1)]",* +826,Aminothiophenols,"[$(c([SH1])c[NX3]([#1,#6])[#1,#6]),$(c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]),$(c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1)]",* +827,Aryl halides,"a[F,Cl,Br,I]",** +828,Primary amines,"[NX3H2][c,CX4&!$([CX4]([NH2])[O,N,S,P])]",*[NH2] +829,Secondary amines,"[NX3H1]([c,CX4&!$([CX4]([NX3H1])[O,S,N,P])])[c,CX4&!$([CX4]([NX3H1])[O,S,N,P])]",*[NH]* +830,Tertiary amines,"[NX3]([c,CX4&!$([CX4]([NX3])[O,S,N,P])])([c,CX4&!$([CX4]([NX3])[O,S,N,P])])[c,CX4&!$([CX4]([NX3])[O,S,N,P])]",*N(*)* +831,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C +832,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C +833,Alkynyl halides,"[F,Cl,Br,I][CX2]#[CX2]",*C#C +834,Benzyl 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+1050,Ene_five_het_D,C1(=C)C(=[OX1])NNC1=[OX1],C=C1C(=O)NNC1=O +1051,Ene_five_het_E,NC=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2,NC=C1*c2ccccc2C1=O +1052,Ene_five_het_F,c1(ccccc1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)S2,O=C1C(=Cc2ccccc2)Sc2ccccc21 +1053,Ene_one_ene_A,C=!@C([!#1])-&@C(=!@[!#1!#6])-&@C(=!@C)[!#1],*C(=C)C(=*)C(*)=C +1054,Ene_one_ester,[#6][#6](=[#8])[#6!H0]=[#6]([#7!H0][#6])[#6](=[#8])[#8][#6],CNC(=CC(C)=O)C(=O)OC +1055,Ene_one_A,a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])Nc2cc3c(cc2)nc(cc3)N([#6])[#6],CN(C)c1ccc2cc(NC(=O)C=C*3:*:*:*:*:*:3)ccc2n1 +1056,Ene_one_D,c([OH1])c-C(=[OX1])[C!H0]=C([#6])[#6],CC(C)=CC(=O)cc[OH] +1057,Ene_one_hal,"[#6][#6]=[#6]([F,Cl,Br,I])[#6](=[OX1])[#6]",*C(=CC)C(C)=O +1058,Ene_cyano_A,[#6](C#[#7])(C#[#7])=Cc1ccccc1,N#CC(=Cc1ccccc1)C#N +1059,Ene_rhod_B,"[#16]1C(=O)NC(=O)C1=[#6!H0][$([#6]Br),$(c[cH]c([F,Cl,Br,I])cc[F,Cl,Br,I]),$(c[cH][cH]cS[CH2,CH3]),$(ccccccccccO[CH2,CH3]),$(c2c([CH2,CH3])n([CH2,CH3])c([CH2,CH3])c2)]",*C=C1SC(=O)NC1=O +1060,Hzone_pipzn,[#6]N1[CH2][CH2]N([CH2][CH2]1)[#7]=[#6!H0]ca,*cC=NN1[CH2][CH2]N(C)[CH2][CH2]1 +1061,Hzone_pyrrol,n1(C)[cH1][cH1][cH1]c1C=NN,Cn1[cH][cH][cH]c1C=NN +1062,Hzone_enamin,"[#7!H0][#7]=[#6][#6]([H,#6])=[#6]([#6])-!@[#7,#8&!H0]",*C(C)=C(*)C=NN +1063,Hzone_anil_di_alk,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6H]=[#7][#7][$([#6](=O)[CH2]Scn),$([#6](=O)[CH2]aan),$([#6](=O)cc[OH1]),$(cn),$([CH2][#6!H0][OH1])])[cH][cH]1",*NN=[CH]c1[cH][cH]c(N(*)*)[cH][cH]1 +1064,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2,C=NNC(=O)c1[cH]c2[cH][cH][cH][cH]c2[cH]c1[OH] +1065,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1,O=C1CC(=O)c2ccccc21 +1066,Keto_keto_beta_zone,"cc[N!H0]N=C([CH2,CH3])[CH2]C([CH2,CH3])=N[N!H0]cc",*C([CH2]C(*)=NNcc)=NNcc +1067,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1],N#CC=C([NH2])C(C#N)C#N +1068,Cyano_pyridone_A,"[#6]1(=[SX1])-,:[#7!H0]-,:*=,:*-,:*=,:[#6]1C#[NX1]",N#CC1=**=*NC1=S +1069,Cyano_pyridone_B,"[#6]1(=,:[#6](-,:[#6](=O)-,:[#7]-,:[#6](=,:[#7]1)[!#1!#6])C#[#7])[#6]",*C1=NC(C)=C(C#N)C(=O)N1 +1070,Cyano_imine_A,[N!H0]N=C(C#[NX1])C=[!#6&!R],*=CC(C#N)=NN +1071,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1,N#CC(C#N)=NNc1ccccc1 +1072,Cyano_cyano_A,"C(C#[NX1])(C#[NX1])C([$(C#[NX1]),$(C=N)])C#[NX1]",*C(C#N)C(C#N)C#N +1073,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9,C1C=CC2C1CNc1ccccc12 +1074,Anil_no_alk,"c1([NH2])[cH][cH]c([#7,#8,CH2,CH3])[cH][cH]1",*c1[cH][cH]c([NH2])[cH][cH]1 +1075,Anil_di_alk_furan_A,"N([CH2,CH3])([CH2,CH3])c1oc(C=N[N!H0]C(=[!#1!#6]))[cH][cH]1",*N(*)c1[cH][cH]c(C=NNC=*)o1 +1076,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7],Nc1c2ccccc2nc2ccccc12 +1077,Thiaz_ene_A,"C1([CH2,CH3,$(cc)])=C([H,CH2,CH3,$(C=O)])SC(N1([H,$([C!H0]),$(cc)]))=[#7!R]",*C1=C(*)N(*)C(=N)S1 +1078,Thiaz_ene_B,"C1([$(NC(=[OX1])cc),NH2])=C(-!@C(=[OX1])N[CH2,CH3])SC(N1[$([CH2][CH]=[CH2]),$(cc)])=[SX1]",*NC(=O)C1=C(*)N(*)C(=S)S1 +1079,Thio_carbonate_A,"[#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]",*c1ccc2c(c1)SC(=*)O2 +1080,Thiophene_amino_Aa,[NH2]c1sc([!#1])c([!#1])c1C=[OX1],*c1sc([NH2])c(C=O)c1* +1081,Thiophene_amino_Ab,"[H,CH2,CH3,$(cc)]c1sc([#7!H0][#6](=O)[#6])c(C(=O)[#8])c1[$(c2ccccc2),$(c3sccc3)]",*c1sc(NC(C)=O)c(C(O)=O)c1* +1082,Thiophene_hydroxy,"[#16]1-,:[#6]=,:[#6]-,:[#6](=,:[#6]1)[OH1]",[OH]C1=CSC=C1 +1083,Sulfonamide_A,"c1(c(c([cH]c([cH]1)[F,Cl,Br,I])[F,Cl,Br,I])[OH1])S(=[OX1])(=[OX1])N",*c1[cH]c(*)c([OH])c(S(N)(=O)=O)[cH]1 +1084,Sulfonamide_B,c1c(ccc(c1)[NH]S(=[OX1])=[OX1])[OH1],O=S(=O)[NH]c1ccc([OH])cc1 +1085,Thio_ketone,"[#6]-,:[CX3](=[SX1])-,:[#6]",CC(C)=S +1086,Anthranil_one_A,"[$(c1c(c(ccc1)C(-cc)=[OX1])[NH&!$([NH][CX3]=[OX1])]),$(c1c(c(ccc1)C(-cc)=[OX1])[NH2])]",* +1087,Diazox_sulfon_A,"N(c1ccccc1)S(=[OX1])(=[OX1])c2c3n[o,s]nc3ccc2",O=S(=O)(Nc1ccccc1)c1cccc2n*nc12 +1088,Dyes3A,"[#7v4,#7+](-,:[#6]=,:[#6])=,:[#6]-[CH]=CN([CX4])[#6]",CN(C)C=CC=*C=C +1089,Dyes5A,"[CH2,CH3][#7](:,-[#6]:[#6])~[#6]-,:[#6]=,:[#6]-[#6]~[#6]:,-[#7]",*N(~CC=CC~C:N):C:C +1090,Rhod_sat_A,"[#7]1-,:[#6](=[#16])-,:[#16]-,:[#6X4]-,:[#6]1=[#8]",O=C1CSC(=S)N1 +1091,Imine_one_fives,[#6]1(=[!#1!#6!R])[#6](=[OX1])[!#1!#6]*=[#6]1,*=C1C=**C1=O +1092,Imine_one_sixes,C1(C(=[OX1])NC(=[OX1])NC1(=[OX1]))=N,N=C1C(=O)NC(=O)NC1=O +1093,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1 +1094,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1 +1095,Thio_dibenzo,"[SX1]=[#6]1-,:[#6]=,:[#6]-,:[!#1!#6]-,:[#6]=,:[#6]1",S=C1C=C*C=C1 +1096,Het_65_A,"[OX1]=CC1=C2N=C([CH2,CH3])C=C([OH1])N2N=C1",*C1=NC2=C(C=O)C=NN2C([OH])=C1 +1097,Het_6_tetrazine,"N~c1[n,$(c(N))][n,c!H0,$(c[N!H0])]c([N!H0,$([OX2][CH2,CH3])])nn1",*c1*:*c(~N)nn1 +1098,Imidazole_A,"[#7]1-,:[#6](-c2ccccc2)=,:[#6](-c3ccccc3)-,:[#7!H0]-,:[#6]1-ca",*cC1NC(c2ccccc2)=C(c2ccccc2)N1 +1099,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH] +1100,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1101,Anisol_A,"c1(O[CH2,CH3])c([H,CH2,CH3])[cH]c(O[CH2,CH3])c([CH2][$([N!H0]C(=[OX1])[CH2][CH2][CH2,CH3]),$([C!H0]([CH2,CH3])[N!H0]C(=[SX1])[N!H0])])[cH]1",*[CH2]c1[cH]c(O*)c(*)[cH]c1O* +1102,Anisol_B,"[CH2,CH3](c4c([cH][cH]c([cH]4)[CH2][N!H0][CX4])O[CH2,CH3])",*Oc1[cH][cH]c([CH2]NC)[cH]c1* +1103,Anthranil_acid_B,"c3cc(C(=[OX1])[N!H0]c4ccccc4C(=[OX1])[OH1])cc1c3C(=[OX1])N([CH2,CH3])C1=[OX1]",*N1C(=O)c2ccc(C(=O)Nc3ccccc3C(=O)[OH])cc2C1=O +1104,Anthranil_acid_C,"[#6]1(=,:[#6]([NH2])-,:[#7](-c7ccccc7C(=[OX1])[OH1])-,:[#7]=,:[#6]1C=[OX1])[$(C#[NX1]),$(C=S)]",*C1=C([NH2])N(c2ccccc2C(=O)[OH])N=C1C=O +1105,Anthranil_acid_D,"c12ncccc1-,:[#6]([NH2])=,:[#6](C(=[OX1])~[OX1,O-])-,:[#16]2",*~C(=O)C1=C([NH2])c2cccnc2S1 +1106,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH] +1107,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH] +1108,Anthranil_acid_G,"c1([cH][cH]c(O[CH2,CH3])[cH]c1(C(=[OX1])[OH1]))[N!H0]cc",*Oc1[cH][cH]c(Ncc)c(C(=O)[OH])[cH]1 +1109,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1 +1110,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1 +1111,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH] +1112,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1 +1113,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1 +1114,Anil_alk_A,"[CH2,CH3]Occ[CH2][N!H0]c1[cH]c2n[cH]n([#6!H0])c2[cH][cH]1",*Occ[CH2]Nc1[cH][cH]c2c([cH]1)n[cH]n2C +1115,Anil_alk_B,"[N!H0](c1[cH][cH]c([CH2,CH3])[cH][cH]1)[CH2][CH2]c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c([CH2][CH2]Nc2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1116,Anil_alk_C,"[N!H0](c1ccccc1)C([#6])([#6])c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c(C(C)(C)Nc2ccccc2)[cH][cH]1 +1117,Anil_alk_D,"[N!H0](c1[cH][cH]c([C!H0]([CH2,CH3])[CH2,CH3])[cH][cH]1)[CH2][CH2]N([CH2,CH3])[CH2,CH3]",*C(*)c1[cH][cH]c(N[CH2][CH2]N(*)*)[cH][cH]1 +1118,Anil_alk_thio,c1ccc2c(c1)C3=C(C([#6])([#6])N2)SSC3=*,*=C1SSC2=C1c1ccccc1NC2(C)C +1119,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2 +1120,Anil_di_alk_F,"c1c(ccc(N([H,CX4])([H,CX4]))c1)[CX4]c2ccc(cc2)N([H,CX4])([H,CX4])",*N(*)c1ccc(Cc2ccc(N(*)*)cc2)cc1 +1121,Anil_di_alk_J,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6!H0]=[#7][#7]=[#6]([#6])-cc)[cH][cH]1",*N(*)c1[cH][cH]c(C=NN=C(C)cc)[cH][cH]1 +1122,Anil_di_alk_I,"[cH]1c([N!H0]C(=[OX1])c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=O)c2ccccc2)[cH]1 +1123,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1 +1124,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12 +1125,Anil_di_alk_ene_B,"[CH2,CH3]N([CH2,CH3])C1=Cc2ccccc2[CH2]1",*N(*)C1=Cc2ccccc2[CH2]1 +1126,Anil_di_alk_furan_B,"[CH2,CH3]N([CH2,CH3])c1[cH][cH]c(o1)[C!H0]=CC#[NX1]",*N(*)c1[cH][cH]c(C=CC#N)o1 +1127,Anil_di_alk_indol,"c12[cH][cH]c(N([CH2,CH3])[CH2,CH3])[cH]c1-,:[#6](S(=[OX1])=[OX1])=,:[#6H]-,:[#7!H0]2",*N(*)c1[cH][cH]c2c([cH]1)C(S(=O)=O)=[CH]N2 +1128,Anil_no_alk_indol_A,"c12[cH][cH]c([NH2])[cH]c1[cH][cH]n2[CH2,CH3]",*n1[cH][cH]c2[cH]c([NH2])[cH][cH]c21 +1129,Anil_NH_alk_A,"c1([N!H0][CH2,CH3])[cH][cH]c2c([cH]1)[#7!H0]-,:[#6](=[OX1])-,:[#7!H0]2",*Nc1[cH][cH]c2c([cH]1)NC(=O)N2 +1130,Anil_NH_alk_B,[N!H0](c1ccacc1)c2ccc([N!H0][C!H0])cc2,CNc1ccc(Nc2cc*cc2)cc1 +1131,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC +1132,Anil_NH_alk_D,"[NH2]c1c([N!H0][C!H0]([#6])[C!H0][CH2,CH3])c[cH][cH][cH]1",*CC(C)Nc1c[cH][cH][cH]c1[NH2] +1133,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1 +1134,Anil_NH_no_alk_B,"[NH2]c1c([N!H0]S(=[OX1])=[OX1])[cH]c([N!H0][CH2,CH3])c([F,Cl,Br,I])[cH]1",*Nc1[cH]c(NS(=O)=O)c([NH2])[cH]c1* +1135,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1 +1136,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH] +1137,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12 +1138,Anil_OC_alk_A,"[cH]1[cH][cH]c2c([cH]1)c3c(o2)[cH]c([N!H0][CH2,CH3])c(O[CH2,CH3])[cH]3",*Nc1[cH]c2oc3[cH][cH][cH][cH]c3c2[cH]c1O* +1139,Anil_OC_alk_B,"c2ccccc2N1C(=[OX1])C([N!H0]c2ccc(O[CH2,CH3])cc2)=C([F,Cl,Br,I])C1=[OX1]",*Oc1ccc(NC2=C(*)C(=O)N(c3ccccc3)C2=O)cc1 +1140,Anil_OC_alk_C,"[H,CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2]c2nccn2",*Oc1[cH][cH][cH][cH]c1N[CH2]c1nccn1 +1141,Anil_OC_alk_D,"[CH2,CH3]Oc1[cH][cH]c([CH2,CH3])[cH]c1[NH][CH2]c2c([CH2,CH3,$(O[CH2,CH3])])cccc2",*Oc1[cH][cH]c(*)[cH]c1[NH][CH2]c1ccccc1* +1142,Anil_OC_alk_E,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2][C!H0]([OH1])[CH2,CH3]",*Oc1[cH][cH][cH][cH]c1N[CH2]C(*)[OH] +1143,Anil_OC_alk_F,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][C!H0]([#16])C=[OX1]",*Oc1[cH][cH][cH][cH]c1NC(S)C=O +1144,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1 +1145,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2] +1146,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1 +1147,Anil_no_alk_B,"[NH2]c1c(n2cccc2)[cH]c([CH2,CH3])c([CH2,CH3])[cH]1",*c1[cH]c([NH2])c(n2cccc2)[cH]c1* +1148,Anil_no_alk_D,"n1c([NH2])c([CH2,CH3])[cH]c([CH2,CH3])c1[NH2]",*c1[cH]c(*)c([NH2])nc1[NH2] +1149,Anil_no_alk_C,"[NH2]c1[cH][cH]c([cH][cH]1)-c2[cH]c(C=[OX1])c([CH2,CH3])o2",*c1oc(-c2[cH][cH]c([NH2])[cH][cH]2)[cH]c1C=O +1150,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12 +1151,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1 +1152,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12 +1153,Hzone_acyl_misc_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C(=[OX1])[N!H0]N=C([H,CH2,CH3])c2cc(*-*-*c3occc3)ccc2",*C(=NNC(=O)c1[cH][cH]c(*)o1)c1cccc(***c2ccco2)c1 +1154,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1 +1155,Hzone_thiophene_A,"[cH]2[cH][cH][cH]c1c2c([C!H0]=N[N!H0]([$(c3nc[cH]s3),$(c[cH][cH]),$(cncncn),$(cnnnn)]))c([H,$([OH1]),CH2,CH3])[a!c]1",*NN=Cc1c(*)*c2[cH][cH][cH][cH]c12 +1156,Hzone_thiophene_B,"c1(s[cH][cH]c1[H,CH2,CH3])[C!H0]=N[N!H0]c2ccccc2",*c1[cH][cH]sc1C=NNc1ccccc1 +1157,Hzone_phenone,"C(c1[cH]cc([H,CX4])[cH][cH]1)(c2[cH][cH]c([H,Cl])[cH][cH]2)=[$(NO[CH2][CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(NO[CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(N[N!H0]C(=[NH1])[NH2]),$([#6!H0][#7])]",*c1c[cH]c(C(=*)c2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1158,Hzone_furan_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[N!H0]c2nccs2",*C(=NNc1nccs1)c1[cH][cH]c(*)o1 +1159,Hzone_furan_B,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[NH]c2ccncc2",*C(=N[NH]c1ccncc1)c1[cH][cH]c(*)o1 +1160,Hzone_furan_C,c1ccccc1N(c2ccccc2)N=[C!H0]c3ac([cH][cH]3)-c4cc(C(=[OX1])[OH1])ccc4,O=C([OH])c1cccc(-c2*c(C=NN(c3ccccc3)c3ccccc3)[cH][cH]2)c1 +1161,Hzone_furan_E,[OH1]C(=[OX1])c1cc(ccc1)-cacC=N[N!H0]C(=[OX1])[CH2][#8],O[CH2]C(=O)NN=Cc*c-c1cccc(C(=O)[OH])c1 +1162,Hzone_naphth_A,"[cH]1[cH][cH]c2[cH][cH]c(C=N[N!H0][$(cc),$(C=[SX1])])[cH]c2c1",*NN=Cc1[cH][cH]c2[cH][cH][cH]cc2[cH]1 +1163,Hzone_acid_A,"[cH]1[cH]c(O[CH2,CH3])[cH]c2C(=N[N!H0]c4[cH][cH]c(C(=[OX1])[OH1])[cH][cH]4)c3[cH]c(O[CH2,CH3])[cH][cH]c3c12",*Oc1[cH][cH]c2c([cH]1)C(=NNc1[cH][cH]c(C(=O)[OH])[cH][cH]1)c1[cH]c(O*)[cH][cH]c12 +1164,Hzone_acid_D,[OH1]C(=[OX1])c1ccc(cc1)NN=[C!H0]c2ac([cH][cH]2)-c3ccccc3,O=C([OH])c1ccc(NN=Cc2*c(-c3ccccc3)[cH][cH]2)cc1 +1165,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1 +1166,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1 +1167,Het_5_C,"N1=C(c2ccccc2)[CH2]C([OH1])([CX4](F)(F)F)N1[$(cccccc),$(C(=S)cccccc)]",*N1N=C(c2ccccc2)[CH2]C1([OH])C(F)(F)F +1168,Het_5_D,"N1(c2ccccc2)N=C([CH2,CH3])[C!H0](S[#6])C1=[OX1]",*C1=NN(c2ccccc2)C(=O)C1SC +1169,Het_5_E,"N1(c2cccc3ccccc23)N=C([CH2,CH3])[CH2]C1=[OX1]",*C1=NN(c2cccc3ccccc23)C(=O)[CH2]1 +1170,Het_5_ene,"C1(=[OX1])C(=C([CH2,CH3])[N!H0][CH2][CH2][CH2,CH3])N=C(c2ccccc2)O1",*[CH2][CH2]NC(*)=C1N=C(c2ccccc2)OC1=O +1171,Het_5_inium,"[#7]1(c2ccccc2)[#6!H0]=[#7+,#7v4](c3ccccc3)[#6](=Nc4ccccc4)N1",C1=*(c2ccccc2)C(=Nc2ccccc2)NN1c1ccccc1 +1172,Het_5_pyrazole_OH,"n1(c2[cH][cH][cH][cH][cH]2)nc([CX4])c([H,C!H0])c1[OH1]",*c1c(C)nn(c2[cH][cH][cH][cH][cH]2)c1[OH] +1173,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1 +1174,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1 +1175,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1 +1176,Het_6_pyridone_NH2,[OH1]c2nc([NH2])acc2[CH2]C(=[OX1])[#8],[NH2]c1*cc([CH2]C(O)=O)c([OH])n1 +1177,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1 +1178,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2 +1179,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1 +1180,Het_65_B,a1a3a(aaa1)[N!H0]N(C3=O)[#6],CN1N*2:*:*:*:*:*:2C1=O +1181,Het_65_C,"C1=CC=CC2=NC([$(C([!#1])=[C!H0]cc),$(coc)])=C(Ncc)N12",*C1=C(Ncc)N2C=CC=CC2=N1 +1182,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1183,Het_65_F,"[#16]1-,:[#6]2:[#6](-,:[#6]([CH2,CH3])=,:[#6]1[CH2,CH3])c(ncn2)NN=C[#6]3=,:[#6]-,:[#6]=,:[#6]-,:[#8]3",*C1=C(*)C2:C(ncnc2NN=CC2=CC=CO2)S1 +1184,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1 +1185,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1 +1186,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12 +1187,Het_65_J,"o1c([#6](~[#8])~[#8])cc2[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c12",*Oc1[cH]c2cc(C(~O)~O)oc2[cH]c1O* +1188,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1 +1189,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O +1190,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12 +1191,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21 +1192,Het_65_pyridone_A,"c1([CH2][CH2,CH3])c([CH2,CH3])c2C(=[!#1!#6X1])N([C!H0][$(C(=O)O),$(cc)])C([H,$(S(C)[CH2,CH3])])=Nc2[a&!c;X2]1",*CN1C(=*)c2c(*c([CH2]*)c2*)N=C1* +1193,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1 +1194,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1 +1195,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1 +1196,Het_66_B,"c1ccc4c(c1)nc(nc4)[N!H0]C2=NC(C=C[N!H0]2)([CH2,CH3])[CH2,CH3]",*C1(*)C=CNC(Nc2ncc3ccccc3n2)=N1 +1197,Het_66_C,c1ccc2nc([C!H0]=C([OH1])[#6])c([C!H0]=C([OH1])[#6])nc2a1,CC([OH])=Cc1nc2*cccc2nc1C=C(C)[OH] +1198,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc +1199,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1 +1200,Het_66_anisole,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0]c2c3c(O[CH2,CH3])ccc(O[CH2,CH3])c3ncc2",*Oc1[cH][cH][cH][cH]c1Nc1ccnc2c(O*)ccc(O*)c12 +1201,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1 +1202,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3 +1203,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21 +1204,Het_565_indole,"[#6!H0]1=,:[#6!H0]-,:[#7]([CH2,CH3])c7c1c9[#6!H0]=,:[#6!H0]-,:[#7](c9c(c7O[CH2,CH3])O[CH2,CH3])[CH2,CH3]",*Oc1c(O*)c2c(c3c1N(*)C=C3)C=CN2* +1205,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21 +1206,Het_666_B,"c1cccc9c1Oc2c(N9[CH2][CH2,CH3])cccc2",*[CH2]N1c2ccccc2Oc2ccccc21 +1207,Het_666_C,"c13cc2ccccc2cc1-,:[#7]([CH2,CH3])-,:[#6](=[OX1])-,:[#6](-cc[N!H0][CH2,CH3])=,:[#7]3",*NccC1=Nc2cc3ccccc3cc2N(*)C1=O +1208,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12 +1209,Het_pyridiniums_B,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:*2=,:[#6]1-,:*=,:[#7+,#7v4](~cc)-,:*=,:[#6]2[H,*]",*C1=**(~cc)=*C2=*1C=CC=C2 +1210,Het_pyridiniums_C,"[#6]1~[#6]~[#6]~[#7+,#7v4]2~[#6](~[#7]1)~[#6]3~[#6]~[#6]~[#6]~[#7](-cc)~[#6]3~[#7]2",ccN1~C~C~C~C2C~1~N*1~C~C~CN~C~1~2 +1211,Het_thio_5_A,"[CH2,CH3][SX2]c1n(-!@[CH2,CH3])c(-c2ccccc2)[cH]n1",*Sc1n[cH]c(-c2ccccc2)n1* +1212,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1 +1213,Het_thio_5_C,"[SX1]=[#6]1-,:[#7!H0]-,:[#7]=,:[#6](c2[cH][cH]c(O[CH2,CH3])[cH][cH]2)-,:[#8]1",*Oc1[cH][cH]c(C2=NNC(=S)O2)[cH][cH]1 +1214,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1 +1215,Het_thio_5_imine_B,"N1([CH2,CH3])C(=S)N(-cc)C(=N-cc)C1=N-cc",*N1C(=S)N(cc)C(=Ncc)C1=Ncc +1216,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc +1217,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1 +1218,Het_thio_6_furan,"[CH2,CH3][SX2]c1nc(-c2o[cH][cH][cH]2)c(-c3o[cH][cH][cH]3)nn1",*Sc1nnc(-c2[cH][cH][cH]o2)c(-c2[cH][cH][cH]o2)n1 +1219,Het_thio_65_A,"[#7]1=,:[#6]([SX2][CH2,CH3])-,:[#7]=,:[#7]-,:[#6]2=,:[#6]1-,:[#6]([CH2,CH3])=,:[#7]-,:[#7]2-c3cccccc3",*SC1=NC2=C(N=N1)N(c1cccccc1)N=C2* +1220,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1 +1221,Het_thio_65_C,"n1c2ccccc2n([CH2,CH3])c1S[CH2]C(=[OX1])[N!H0]N=[C!H0][C!H0]=[C!H0]",*n1c(S[CH2]C(=O)NN=CC=C)nc2ccccc21 +1222,Het_thio_65_D,"c1(S[CH2]C(=[OX1])[NH]-cc)nc2[cH]c([F,Cl,Br,I])c[cH]c2[nH]1",*c1c[cH]c2[nH]c(S[CH2]C(=O)[NH]cc)nc2[cH]1 +1223,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1 +1224,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1 +1225,Het_thio_67_A,"[CH2,CH3][SX2]c1nc2OC=Ncc-c2nn1",*Sc1nnc2c(n1)OC=Ncc-2 +1226,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21 +1227,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12 +1228,Het_thio_656c,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]2-,:[#7+,#7v4]=,:[#6]3-,:[#7](N=C(c5ccccc5)[CX4]S3)-,:[#6]12",*1=C2SCC(c3ccccc3)=NN2C2C=CC=CC12 +1229,Het_thio_665,"c1ccc7c(c1)NC3=C(S7)SC(=C3)[CH2,CH3]",*C1=CC2=C(S1)Sc1ccccc1N2 +1230,Het_thio_666_A,"[cH]1[cH][cH][cH]c5N([H,CH3,$([CH2][C!H0])])c7c(~[H,$([N!H0][CX4]),$(cc)])c(~[H,$(cc)])c([H,NH2,$([OX2][CX4])])[cH]c7Sc15",*~c1c(~*)c2c([cH]c1*)Sc1[cH][cH][cH][cH]c1N2* +1231,Het_thio_676_A,"c1ccc4c(c1)Sc8[cH][cH]c([cH]c8C(C4)N([H,CX4])([H,CX4]))[H,#8,#16X2,CX4,$(N([H,CX4])[H,CX4])]",*c1[cH][cH]c2c([cH]1)C(N(*)*)Cc1ccccc1S2 +1232,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21 +1233,Het_thio_pyr_A,"n1c(S[C!H0])c(C#[NX1])c(c2ccc(O[Ch2,CH3])cc2)[cH]c1(cc)",*Oc1ccc(c2[cH]c(cc)nc(SC)c2C#N)cc1 +1234,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1 +1235,Het_thio_N_5B,"[#6]1~[#6](~[#7]~[#7]~[#6](~[CH2,CH3])~[CH2,CH3])~[#7]~[#16]~[#6]1",*~C(~*)~N~N~C1~CC~S~N~1 +1236,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1 +1237,Het_thio_N_55,[C!H0]c1nn(c3ccccc3)s2[a!c]acc12,Cc1nn(c2ccccc2)s2*:*cc12 +1238,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2 +1239,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc +1240,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1 +1241,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21 +1242,Styrene_B,"c1ccc4c(c1)[SX2,CX4]c8ccc(cc8C4=CC)[H,Cl,CX4]",*c1ccc2c(c1)C(=CC)c1ccccc1*2 +1243,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2 +1244,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21 +1245,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc +1246,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21 +1247,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN +1248,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S +1249,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N +1250,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1 +1251,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1 +1252,Ene_five_het_G,"C1(=[OX1])C(=[C!H0][$(c2ccccc2),$(c2ccc[a!c]2)])N=C(aaa)[#16,$(Naa)]1",*C=C1N=C(*:*:*)*C1=O +1253,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S +1254,Ene_five_het_I,c1(ccco1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2,O=C1C(=Cc2ccco2)*c2ccccc21 +1255,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S +1256,Ene_five_het_K,"[#7]1([#6])-,:[#6H]=,:[#6H]-,:[#6H]=,:[#6]1([CH]=C2C(=[OX1])[!#6]C=,:*2)",CN1[CH]=[CH][CH]=C1[CH]=C1*=C*C1=O +1257,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1 +1258,Ene_five_het_M,"C1=,:C[O,S]C(=CC=[OX1])C1=[OX1]",O=CC=C1*C=CC1=O +1259,Ene_five_het_N,"C1(=[OX1])C(=[C!H0]c2cc([F,Cl,Br,I])ccc2O[CH2,CH3])N=C(S[CH2,CH3])S1",*Oc1ccc(*)cc1C=C1N=C(S*)SC1=O +1260,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1 +1261,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O +1262,Ene_six_het_D,[OX1]=C1NNC(aa)=NC1=[C!H0],*:*C1=NC(=C)C(=O)NN1 +1263,Ene_quin_methide,"aaC([H,$(C#[NX1])])=[#6]1-,:[#6]=,:[#6]-,:[#6](=[OX1,N!R])-,:[#6]=,:[#6]1",*C(*:*)=C1C=CC(=*)C=C1 +1264,Ene_rhod_C,"S1C(=Ncc)N([H,$([CH2][CH2]O),$(cc)])C(=[OX1])C1(=[C!H0][$(cccCl),$(c[a!c])])",*C=C1SC(=Ncc)N(*)C1=O +1265,Ene_rhod_D,"S1C(=!@N[H,$([N!H0](N)cc)])N([H,$(cnccs)])C(=[OX1])C1=[C!H0]cc[Cl,$(O[C!H0])]",*ccC=C1SC(=N*)N(*)C1=O +1266,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S +1267,Ene_rhod_F,"n1ccc([C!H0]=C2C(=[OX1])NC(=[!#1!#6])N2)c1[CH2,CH3]",*c1nccc1C=C1NC(=*)NC1=O +1268,Ene_rhod_G,[OH1][CX3](=[OX1])c1cccc(c1)cac[C!H0]=C2C(=[!#1!#6])NC(=[!#1!#6])[!#1!#6]2,*=C1*C(=Cc*cc2cccc(C(=O)[OH])c2)C(=*)N1 +1269,Ene_rhod_H,"N1=C([CH2,CH3])C(=[OX1])N=C2N1C(=[OX1])C(=[C!H0]cc)S2",*C1=NN2C(=O)C(=Ccc)SC2=NC1=O +1270,Ene_rhod_I,"N1([CH2,CH3])C(=S)[N!H0]C(=[C!H0]c2cc(Br)ccc2)C1(=O)",*N1C(=O)C(=Cc2cccc(Br)c2)NC1=S +1271,Ene_rhod_J,"[CH2,CH3]N1C(=[#16,#7])[!#6]C(=[#6]2-,:[#6H]=,:[#6H]cc-,:[#7]2[CH2,CH3])C1=[OX1]",*N1cc[CH]=[CH]C1=C1*C(=*)N(*)C1=O +1272,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1 +1273,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O +1274,Ene_misc_C,"c1ccc4c(c1)N(C(C=C4)([CH2,CH3])[CH2,CH3])C(=[OX1])[N!H0]c3ccc(c(c3)O[CH2,CH3])O[CH2,CH3]",*Oc1ccc(NC(=O)N2c3ccccc3C=CC2(*)*)cc1O* +1275,Ene_misc_D,"c12[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c1C([#6])=C([#6])S[CH2]2",*Oc1[cH]c2c([cH]c1O*)C(C)=C(C)S[CH2]2 +1276,Ene_misc_E,"c1(O[CH2,CH3])c(O[CH2,CH3])[cH]c2C=C[C!H0]Sc2[cH]1",*Oc1[cH]c2c([cH]c1O*)SCC=C2 +1277,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1 +1278,Dhp_amino_CN_A,"[NH2]C1=C(C#[NX1])[C!H0](cc)C([CH2,CH3])=C(C=C)O1",*C1=C(C=C)OC([NH2])=C(C#N)C1cc +1279,Dhp_amino_CN_B,"[NX3H2,OX2H1]C1=C(C#[NX1])[C!H0](cc)c2c(n(C)nc2)O1",*C1=C(C#N)C(cc)c2cnn(C)c2O1 +1280,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N +1281,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21 +1282,Dhp_amino_CN_E,"[CH2,CH3][SX2]C1=C(C#[NX1])[C!H0](cc)C(C#[NX1])C(=O)N1",*SC1=C(C#N)C(cc)C(C#N)C(=O)N1 +1283,Dhp_amino_CN_F,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](c2cccs2)-,:[#6](C(=[OX1])O[#6])=,:[#6]([CH2,CH3])-,:[#8]1",*C1=C(C(=O)OC)C(c2cccs2)C(C#N)=C([NH2])O1 +1284,Dhp_amino_CN_G,"[SX2]1C=C(C#[NX1])C([#6])(C=[OX1])C([$(C=[OX1]),$(C#[NX1])])=C1[NH2]",*C1=C([NH2])SC=C(C#N)C1(C)C=O +1285,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N +1286,Dhp_keto_A,"[#7]1([H,CX4])-,:[#6]=,:[#6](C(=[OX1])ccc)-,:[#6]([#6])-,:[#6]([$(C=[OX1]),$(C#[NX1])])=,:[#6]1[CH3]",*C1=C([CH3])N(*)C=C(C(=O)ccc)C1C +1287,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2] +1288,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1 +1289,Сyano_keto_A,"[CH2,CH3][C!H0](C#[NX1])C(=[OX1])[#6]",*C(C#N)C(C)=O +1290,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N +1291,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N +1292,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc +1293,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O +1294,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O +1295,Cyano_pyridone_C,"C1(C([CH2,CH3])=C(C#[NX1])C(~[#8])~[#7]~[#6]1(~[#8]))=[C!H0]cc",*C1=C(C#N)C(~O)~N~C(~O)C1=Ccc +1296,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O +1297,Cyano_pyridone_E,"ac[#6]1=,:[#6!H0]-,:[#6](co)=,:[#6](C#[NX1])-,:[#6](=[OX1])-,:[#7!H0]1",*cC1=CC(co)=C(C#N)C(=O)N1 +1298,Cyano_pyridone_G,"N1(c2ccc(O[CH2,CH3])cc2)C(=[OX1])C(C#[NX1])=CC(n3cncc3)=N1",*Oc1ccc(N2N=C(n3ccnc3)C=C(C#N)C2=O)cc1 +1299,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12 +1300,Thio_aldehyd_A,"[#1,#6][C!H0](=[SX1])",*C=S +1301,Thio_amide_A,"[#6!H0]1=,:[#6]-,:[#8]-,:[#6](=,:[#6!H0]1)C(=[SX1])N5[CH2][CH2]*[CH2][CH2]5",S=C(C1=CC=CO1)N1[CH2][CH2]*[CH2][CH2]1 +1302,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc +1303,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1 +1304,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C +1305,Thio_amide_E,"c1cccnc1C(=S)[N!H0]c2ccccc2O[CH2,CH3]",*Oc1ccccc1NC(=S)c1ccccn1 +1306,Thio_amide_F,acC(=S)[N!H0][N!H0]ca,*cNNC(=S)c* +1307,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1 +1308,Thio_ester_B,"ccC(=[SX1])[SX2][C!H0][CH2,CH3,$(cc)]",*CSC(=S)cc +1309,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1 +1310,Thio_ene_amine_A,"S=CC([CH2,CH3])=C([CH2,CH3])N([CH2,CH3])[CH2,CH3]",*C(C=S)=C(*)N(*)* +1311,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O +1312,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1 +1313,Thio_pyridine_A,c1(nanc(c2o[cH][cH][cH]2)n1)S[CX4],CSc1n*nc(c2[cH][cH][cH]o2)n1 +1314,Thio_thiomorph_Z,"[OX1]=C(N3CCSCC3)c9c([cH][cH][cH][cH]9)S[CH2,CH3]",*Sc1[cH][cH][cH][cH]c1C(=O)N1CCSCC1 +1315,Thio_urea_A,"c1c([N!H0][CX3](=[SX1])[N!H0][CH2][CH2][CH2]N([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1316,Thio_urea_B,"c1c([#7!H0]C(=S)[#7!H0][CH2][CH2][#7]([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1317,Thio_urea_C,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]C(=[OX1])c2a[a!c]cc2,O=C(NNC(=S)Nc1ccccc1)c1*:*cc1 +1318,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1 +1319,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1 +1320,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1 +1321,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1 +1322,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1 +1323,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1 +1324,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S +1325,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12 +1326,Thio_urea_L,[CX4][SX2]C(=N-aaaa)[N!H0]N=[#6],*:*:*:*N=C(NN=C)SC +1327,Thio_urea_M,"cc[#7]([CH2,CH3])[CH2][CH2][CH2][#7!H0]C(=S)[#7!H0]c1c([F,Cl,Br,I])[cH]c([CH2,CH3])[cH][cH]1",*c1[cH][cH]c(NC(=S)N[CH2][CH2][CH2]N(*)cc)c(*)[cH]1 +1328,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1 +1329,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1 +1330,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2 +1331,Thio_urea_Q,"[cH]1[cH][cH][cH]c2[cH][cH][cH]c(c12)C([CH2,CH3])=N[N!H0]C(=S)[N!H0]ccc",*C(=NNC(=S)Nccc)c1[cH][cH][cH]c2[cH][cH][cH][cH]c12 +1332,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1 +1333,Thio_carbam_A,"[CH2,CH3]SC(=S)[N!H0][CH2]-cc",*SC(=S)N[CH2]cc +1334,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1 +1335,Thio_carbonate_B,"[OX1]=[#6]1-,:[#16]c2cccc(O[CH2,CH3])c2-,:[#8]1",*Oc1cccc2c1OC(=O)S2 +1336,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N +1337,Thio_imine_ium,"[CX4][#7+,#7v4]([CX4][OH1])=CS[C!H0]",CSC=*(C)C[OH] +1338,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12 +1339,Thiophene_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=CC(=[OX1])c1c([SX2])sc([$(C#[NX1]),$(C=[OX1])])c1",*c1cc(C(=O)C=CN(*)*)c(S)s1 +1340,Thiophene_D,"s1[cH][cH]c(O[CH2,CH3])c1C(=[OX1])[N!H0][N!H0]",*Oc1[cH][cH]sc1C(=O)NN +1341,Thiophene_E,"c1(sc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])C(=[OX1])[NH]c2nccs2",*C(C(=O)[NH]c1nccs1)c1[cH][cH]c(*)s1 +1342,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C +1343,Thiophene_amino_B,"c2ccccc2[#7!H0]c1sc([$([#6]=[#8]),$(C#[#7]),$([#6]([#8!H0])=[#6])])c([#7])c1[$(C#[#7]),$([#6](n)n)]",*c1sc(Nc2ccccc2)c(*)c1N +1344,Thiophene_amino_C,"[C!H0][CH2]c1sc([N!H0]C(=[OX1])CCC=[OX1])c([$(C(=[OX1])O),$(C#[NX1])])c1[CH2,CH3]",*c1c([CH2]C)sc(NC(=O)CCC=O)c1* +1345,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N +1346,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1 +1347,Thiophene_amino_F,[NH2]c1sc([NH]C(=[OX1])c3ccccc3)c(C#[NX1])c1c2aaaaa2,N#Cc1c([NH]C(=O)c2ccccc2)sc([NH2])c1c1*:*:*:*:*1 +1348,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH] +1349,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc +1350,Keto_naphthol_A,"[#6]C(=[OX1])c1cccc2cccc([OH1,NH2])c12",*c1cccc2cccc(C(C)=O)c12 +1351,Keto_thiophene,"c1(sc2ccccc2c1([CH2,CH3]))C(=[OX1])[CH2][CH2,CH3]",*[CH2]C(=O)c1sc2ccccc2c1* +1352,Keto_phenone_A,c1cccc5c1C(c8c5nacc8)=[OX1],O=C1c2ccccc2c2n*ccc21 +1353,Keto_phenone_B,c1cccc5c1C(C8C5=N[!#1!#6]=CC8)=[OX1],O=C1C2CC=*N=C2c2ccccc21 +1354,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12 +1355,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1 +1356,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1 +1357,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O +1358,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH] +1359,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O +1360,Keto_keto_beta_F,"[CH2,CH3]C([OH1])=C(C(=[OX1])[CH2,CH3])[C!H0]C#C",*C(=O)C(CC#C)=C(*)[OH] +1361,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21 +1362,Thiaz_ene_C,"[#6]1([F,Cl,Br,I,$([#7v4R,#7v4R+](=,:[#6R])-,:[#6R])])=,:[#6](-!@C=N)-,:[#16]-,:[#6](=[OX1])-,:[#7]1",*C1=C(C=N)SC(=O)N1 +1363,Acyl_het_A,"[#7v4,#7+](=,:*-,:*=,:*)-,:*=O",*=**=**=O +1364,Anil_di_alk_G,"[CX4]N([CX4])c1[cH][cH]c([#6]2=,:[#7]-,:[#6]=,:[#6]-,:*2)[cH][cH]1",CN(C)c1[cH][cH]c(C2=NC=C*2)[cH][cH]1 +1365,Anil_di_alk_H,"[cH]1c([N!H0]S(=[OX1])(=[OX1])c2caccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NS(=O)(=O)c2c*ccc2)[cH]1 +1366,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1 +1367,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21 +1368,Anil_di_alk_O,"[cH]1c([N!H0]C(=S)[N!H0]c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=S)Nc2ccccc2)[cH]1 +1369,Anil_di_alk_P,"[CH2,CH3]N([CH2,CH3])c1cc2nc(S[CH2,CH3])sc2cc1",*Sc1nc2cc(N(*)*)ccc2s1 +1370,Anil_di_alk_ene_A,"[CH2,CH3]N([CH2,CH3])C1=[C!H0]c2ccccc2[SX2]c3ccccc13",*N(*)C1=Cc2ccccc2Sc2ccccc21 +1371,Anil_di_alk_dhp,"N1C=C(C=[OX1])C(-c3ccc(N([CH2,CH3])[CH2,CH3])cc3)C2=C1(~[#7]~[#6](~[#16])~[#7]~[#6]2~[#7])",*N(*)c1ccc(C2C(C=O)=CNC3=C2C(~N)~N~C(~S)~N~3)cc1 +1372,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21 +1373,Anil_di_alk_coum,"c2ccccc2N([C!H0])[C!H0][C!H0][C!H0][N!H0]C(=[OX1])[#6]1-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6](=[OX1])-,:[#8]-,:[#6]([CH2,CH3])=,:1",*C1=CC(=O)OC(*)=C1C(=O)NCCCN(C)c1ccccc1 +1374,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1 +1375,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O +1376,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O +1377,Ene_one_amide_A,"c1ccccc1[C!H0]NC(=[OX1])C([N!H0][CH2,CH3])=[C!H0]C(=[OX1])c2ccc(O[CH2,CH3])cc2",*NC(=CC(=O)c1ccc(O*)cc1)C(=O)NCc1ccccc1 +1378,Ene_one_amide_B,"c13ccc2ccccc2c1[C!H0][CX4]NC3=[C!H0]C(=[OX1])N([CH2,CH3])[CH2,CH3]",*N(*)C(=O)C=C1NCCc2c1ccc1ccccc21 +1379,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1 +1380,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O +1381,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C +1382,Imine_one_B,"[N!H0](c1ccccc1)N=C(C(=[OX1])[CH2,CH3])[N!H0][$([N!H0]),$(cc)]",*NC(=NNc1ccccc1)C(*)=O +1383,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1 +1384,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1 +1385,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21 +1386,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C +1387,Imine_imine_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=NC([CH2,CH3])=NN([CH2,CH3])cc",*C(N=CN(*)*)=NN(*)cc +1388,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O +1389,Imine_one_fives_C,cc[N!R]=C2C(=[!#1!#6])c5ccccc5N2,*=C1C(=Ncc)Nc2ccccc21 +1390,Imine_one_fives_D,C1(=[!#1!#6])C(N=CS1)=O,*=C1SC=NC1=O +1391,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH] +1392,Imine_naphthol_A,"c12c([cH][cH][cH][cH]1)c(c([cH][cH]2)C(=N-cc)[CH2,CH3])[OH1]",*C(=Ncc)c1[cH][cH]c2[cH][cH][cH][cH]c2c1[OH] +1393,Pyrrole_C,"[#7]1([CX4])-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6!H0]=,:[#6]1cc",*C1=CC=C(cc)N1C +1394,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S +1395,Pyrrole_E,"[#7]1(c2[cH]a[a!c]a2)-,:[#6]([CX4])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CX4]",CC1=CC=C(C)N1c1*:*:*[cH]1 +1396,Pyrrole_F,[cH]1[cH]n(-c2[a!c]ccc2C#[NX1])c[cH]1,N#Cc1cc*c1-n1c[cH][cH][cH]1 +1397,Pyrrole_G,"n1(c2c[cH]c([$([NH2]),$(cn)])c[cH]2)[cH][cH][cH][cH]1",*c1c[cH]c(n2[cH][cH][cH][cH]2)c[cH]1 +1398,Pyrrole_H,"C1=[Nv4,N+]([#6])CC[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]12",C*1=CC2=CC=CN2CC1 +1399,Pyrrole_I,"[#7]1([CH2,CH3])-,:[#6]2=,:[#6](-,:[#6]:[#6]-,:[#6]2=[OX1])-,:[#6]=,:[#6]1[CH2,CH3]",*C1=CC2=C(C(=O)C:C2)N1* +1400,Pyrrole_J,"[#6]1(=,:[#6]2-,:[#6](=,:[#6](-,:[#7]1C(O)=[OX1])[CH2,CH3])S[CH2]S2)[CH2,CH3]",*C1=C2S[CH2]SC2=C(*)N1C(O)=O +1401,Pyrrole_K,"[#6]1(-,:[#7!H0]-,:[#6](c2[cH][cH][cH][cH][cH]2)=,:[#6]([CH2,CH3])-,:[#6H]=,:1)C(=[OX1])[OH1]",*C1=C(c2[cH][cH][cH][cH][cH]2)NC(C(=O)[OH])=[CH]1 +1402,Pyrrole_L,"[n!H0]1c(C(=[OX1])O[CH2,CH3])c([CH2,CH3])c([CH2][CH2,CH3])c1[CH2][CH2,CH3]",*[CH2]c1nc(C(=O)O*)c(*)c1[CH2]* +1403,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1 +1404,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1 +1405,Pyrrole_O,"[#7]1([CH2,CH3])-,:[#6]([CH2,CH3])=,:[#6](C(=[OX1])[#6])-,:[#6]=,:[#6]1-cc",*C1=C(C(C)=O)C=C(cc)N1* +1406,Thiaz_ene_D,"c2ccccc2[#7][#6]1=,:[#7+,#7v4]-,:[#6](c3ccccc3)=,:[#6][#16]1",*1=C(Nc2ccccc2)SC=C1c1ccccc1 +1407,Thiaz_ene_E,"C1(S[#6R])=C([C!H0]([#6])[#6])SC(N1([H,CH2,CH3]))=[OX1]",*N1C(=O)SC(C(C)C)=C1SC +1408,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21 +1409,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O +1410,Quinone_D,"[!#1!#6]=[#6]1[#6]=,:[#6][#6]=,:[#6][#6]1=[!#1!#6]",*=C1C=CC=CC1=* +1411,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1 +1412,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1 +1413,Diazox_C,N2=Nc1n[a!c]nc1N=Ncc2,*1nc2c(n1)N=NccN=N2 +1414,Diazox_D,[C!H0]1([OH1])c2n[a!c]nc2[C!H0]([OH1])C=C1,[OH]C1C=CC([OH])c2n*nc21 +1415,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2] +1416,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1 +1417,Sulfonamide_C,[cH]1c([N!H0]S(=[OX1])(=[OX1])c2ccc([!#1!#6])cc2)[cH]c3c(O[CH2]O3)[cH]1,*c1ccc(S(=O)(=O)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)cc1 +1418,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1 +1419,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc +1420,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1 +1421,Sulfonamide_G,"[CH3]c5nc([N!H0]S(c2[cH][cH]c([cH][cH]2)O[CH2][CH2][CH2,CH3])(=[OX1])(=[OX1]))[cH][cH][cH]5",*[CH2][CH2]Oc1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]c([CH3])n2)[cH][cH]1 +1422,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1 +1423,Sulfonamide_I,"S(=[OX1])(=[OX1])(c1cn([CH2,CH3])cn1)[N!H0]c2cnn([CH2]ccO[CH2,CH3])c2",*Occ[CH2]n1cc(NS(=O)(=O)c2cn(*)cn2)cn1 +1424,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1 +1425,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc +1426,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1 +1427,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1 +1428,Thiazole_amine_B,"c1(ccc([CH2,CH3])cc1)-c2nc([NH2])sc2[CH3]",*c1ccc(-c2nc([NH2])sc2[CH3])cc1 +1429,Thiazole_amine_C,"c1([N!H0][CH2]c2[cH][cH][cH]o2)nc(aaa([$(O[CH2,CH3]),CH2,CH3])aa)[cH]s1",**(:*:*):*:*c1[cH]sc(N[CH2]c2[cH][cH][cH]o2)n1 +1430,Thiazole_amine_D,"[#16]1-,:[#6]([N!H0]c2c([CH2,CH3,$(cc)])cccc2)=,:[#7+,#7v4]([CH2,CH3])-,:[#6]([#6])=,:[#6H]1",**1=C(Nc2ccccc2*)S[CH]=C1C +1431,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O +1432,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1 +1433,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1 +1434,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1 +1435,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1 +1436,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3 +1437,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1 +1438,Thiazole_amine_M,"c1([N!H0]cc[CH2,CH3])nc(c2ccncc2)[cH]s1",*ccNc1nc(c2ccncc2)[cH]s1 +1439,Thiazole_amine_N,"[CH2,CH3]Oc1[cH][cH]c(O[CH2,CH3])[cH]c1[N!H0]c2scc(-c3ccc(O[CH2,CH3])cc3)n2",*Oc1ccc(-c2csc(Nc3[cH]c(O*)[cH][cH]c3O*)n2)cc1 +1440,Furan_acid_A,"c1(oc([CH2,CH3])c([CH2]Occ)[cH]1)[CX3](=[OX1])[OH1]",*c1oc(C(=O)[OH])[cH]c1[CH2]Occ +1441,Furan_A,"c1(oc([CH2,CH3])[cH][cH]1)[C!H0]([OH1])C#C[CX4]",*c1[cH][cH]c(C([OH])C#CC)o1 +1442,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N +1443,Colchicine_B,"[CH2,CH3]Sc1ccc(cc1)C2=CC(=[OX1])[#6]3=,:[#6]-,:[#8]-,:[#6]=,:[#6]3C([OH1])=C2",*Sc1ccc(C2=CC(=O)C3=COC=C3C([OH])=C2)cc1 +1444,Colchicine_het,"c1cccc3-,:[#7]([CH2,CH3])-,:[#6](=NN=[#6]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]2)-,:[#16]-,:c13",*N1C(=NN=C2C=CC=CC=C2)Sc2ccccc21 +1445,Rhod_sat_B,"N1(c2c([CH2,CH3])cccc2)C(=S)N([CH2]aaaaa)[CH2]C1=[OX1]",*c1ccccc1N1C(=O)[CH2]N([CH2]*:*:*:*:*)C1=S +1446,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1 +1447,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O +1448,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1 +1449,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1 +1450,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1 +1451,Melamine_A,"o1[cH][cH][cH]c1[CH2][N!H0]c1c2ccccc2nc([N!H0]c4c([H,CH2,CH3,SX2,$(O[C!H0])])cc([H,CH2,CH3,SX2,$(O[C!H0])])c([H,CH2,CH3,SX2,$(O[C!H0])])c4)n1",*c1cc(*)c(Nc2nc(N[CH2]c3[cH][cH][cH]o3)c3ccccc3n2)cc1* +1452,Melamine_B,"n1c(N([CH2,CH3])[CH2,CH3])nc(N([CH2,CH3])[CH2,CH3])nc1N([C!H0])C=[OX1]",*N(*)c1nc(N(*)*)nc(N(C)C=O)n1 +1453,Imidazole_B,"[CH2,CH3][CH2]S[CH2][#6]1=,:[#6]-,:[#7!H0]-,:[#6]=,:[#7]1",*[CH2]S[CH2]C1=CNC=N1 +1454,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2 +1455,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1 +1456,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1 +1457,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23 +1458,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2 +1459,Naphth_ene_one_A,"c1cc3c4c(c1)cccc4C(=CC3=[OX1])O[CH2,CH3]",*OC1=CC(=O)c2cccc3cccc1c23 +1460,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F +1461,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2 +1462,Coumarin_A,"c1(O[C!H0])[cH][cH]c2c3[cH][cH]c(O[CH2,CH3])[cH]c3-,:[#6](=[OX1])-,:[#8]c2c1",*Oc1[cH][cH]c2c([cH]1)C(=O)Oc1cc(OC)[cH][cH]c12 +1463,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O +1464,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1 +1465,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1 +1466,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1 +1467,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O +1468,Coumarin_G,"c1c([F,Cl,Br,I])cc2c(c1[F,Cl,Br,I])OC(=[N!H0])C(C(=[OX1])[NH2])=[C!H0]2",*c1cc(*)c2c(c1)C=C(C([NH2])=O)C(=N)O2 +1469,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1 +1470,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O +1471,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O +1472,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1 +1473,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH] +1474,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH] +1475,Tetrazole_A,"[CH2,CH3][#6]1=,:[#7]-,:[#7]=,:[#7]-,:[#7]1c2[cH][cH]c(O[CH3])[cH][cH]2",*C1=NN=NN1c1[cH][cH]c(O[CH3])[cH][cH]1 +1476,Misc_aminal_acid,"c1ccc4c(c1)COC(N4C(=[OX1])[CH2,CH3])(C(=[OX1])[OH1])[CH2,CH3]",*C(=O)N1c2ccccc2COC1(*)C(=O)[OH] +1477,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1 +1478,Misc_anilide_A,"c1([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH][cH]c([CH2,CH3])c([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH]1",*c1[cH][cH]c(NC(=O)[CH2][CH2]cc)[cH]c1NC(=O)[CH2][CH2]cc +1479,Misc_anilide_B,"c1([N!H0]C(=[OX1])[N!H0][CH2][CH2][CH2,CH3])c([CH2,CH3])[cH]c(Br)[cH]c1[CH2,CH3]",*[CH2][CH2]NC(=O)Nc1c(*)[cH]c(Br)[cH]c1* +1480,Misc_anisole_A,"c1(c([cH]c5c([cH]1)c([cH]c([cH]5)c3[cH][cH]c(c([cH]3)O[CH2,CH3])O[CH2,CH3])[N!H0][CH3])O[CH2,CH3])O[CH2,CH3]",*Oc1[cH][cH]c(c2[cH]c(N[CH3])c3[cH]c(O*)c(O*)[cH]c3[cH]2)[cH]c1O* +1481,Misc_anisole_B,"c1([cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH][cH]1)C(=[OX1])[CH2]N([CH2,CH3])c2ccc([CH2,CH3])cc2",*Oc1[cH][cH]c(C(=O)[CH2]N(*)c2ccc(*)cc2)[cH]c1O* +1482,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3] +1483,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1 +1484,Misc_furan_A,"c3c([CH2,CH3])c([CH2,CH3])oc3[CH2]N[CH2][C!H0](O[CH2,CH3])[CH2]Oc1ccc2c(O[CH2]O2)c1",*OC([CH2]N[CH2]c1cc(*)c(*)o1)[CH2]Oc1ccc2c(c1)O[CH2]O2 +1485,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1 +1486,Misc_phthal_thio_N,"c1(c2ccccc2)nc(N([CH2,CH3])[CH2][CH2]NC(=[OX1])c3c(C(=[OX1])[OH1])cccc3)sn1",*N([CH2][CH2]NC(=O)c1ccccc1C(=O)[OH])c1nc(c2ccccc2)ns1 +1487,Misc_pyridine_OC,"[OX1]=C(c1[cH]c(O[CH3])nc(O[CH3])[cH]1)[N!H0][C!H0]([CH2,CH3])[CH2,CH3]",*C(*)NC(=O)c1[cH]c(O[CH3])nc(O[CH3])[cH]1 +1488,Misc_pyrrole_benz,"[#7]1(-c2[cH][cH][cH][cH]c2C(=[OX1])[N!H0][C!H0]([CH2,CH3])[CH2]O-cc)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",*C([CH2]Occ)NC(=O)c1[cH][cH][cH][cH]c1N1C=CC=C1 +1489,Misc_pyrrole_thiaz,"c1([C!H0]([CH2,CH3])[CH2][CH2]N[CH2]c2[n!H0]ccc2)nc(-c3ccccc3)[c!H0]s1",*C([CH2][CH2]N[CH2]c1cccn1)c1nc(-c2ccccc2)cs1 +1490,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH] +1491,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH] +1492,Misc_urea_A,"c1(C([CX4])([CX4])[N!H0]C(=[OX1])N([CH2][CH2,CH3])[CH2][CH2][CH2][CH2]-cc)[cH][cH][cH]c(C(=[CH2])[CH2,CH3])[cH]1",*[CH2]N([CH2][CH2][CH2][CH2]cc)C(=O)NC(C)(C)c1[cH][cH][cH]c(C(*)=C)[cH]1 +1493,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1 +1494,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1 +1495,Pyrazole_amino_A,"[#6]1=,:[#6]([NH2])-,:[#7]-,:[#7]=,:[#6]1-[#6]2=,:[#6]([CH2,CH3])-,:[#8]-,:[#6!H0]=,:[#6!H0]2",*C1=C(C2=NNC([NH2])=C2)C=CO1 +1496,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1 +1497,Indole_3yl_alk_B,"c12[cH][cH][cH][cH]c1-,:[#6]([CH2,CH3])=,:[#6](-cc)-,:[#7]2-!@cc",*C1=C(cc)N(cc)c2[cH][cH][cH][cH]c21 +1498,Mannich_B,"c1c[cH]c2O[CH2]N(ccO[CH2,CH3])[CH2]c2[cH]1",*OccN1[CH2]Oc2[cH]cc[cH]c2[CH2]1 +1499,Mannich_catechol_A,"[cH]1c([#8])c([#8])[cH]c2c1O[CH2]N([CH2,CH3])[CH2]2",*N1[CH2]Oc2[cH]c(O)c(O)[cH]c2[CH2]1 +1500,Dyes7A,"c1ccccc1N([CH2,CH3])[C!H0]=[C!H0]C=!@[C!H0][C!H0]=CC=&@Nc2ccccc2",*N(C=CC=CC=CC=Nc1ccccc1)c1ccccc1 +1501,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1 +1502,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1 +1503,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH] +1504,Retinoic acid derivatives_1,"[$([OH1][CX3](=[OX1])c1[cH][cH]c(-c2c[cH]c3[cH]c([H,CX4])c([H,CX4])[cH]c3[cH]2)[cH][cH]1),$([OH1][CX3](=[OX1])c1[cH]c2[cH]cc(-c3[cH]c([H,CX4])c([H,CX4])[cH][cH]3)[cH]c2[cH][cH]1)]",* +1505,Thiazole_amine_I,"[CH2,CH3][N!H0]C=N[N!H0][#6]1=,:[#7]-,:[#6](-cc)=,:[#6!H0]-,:[#16]1",*NC=NNC1=NC(cc)=CS1 +1506,Indol_3yl_alk,"[H,CH2,CH3][#7]1-,:[#6]([CH2,CH3,$([a!c](:[#6]-,:[#7])),$([C!H0][#7]),$([C!H0]([CH2,CH3])[N!H0][CH2,CH3]),$([C!H0]([CH2,CH3])[CH2][N!H0][CH2,CH3])])=,:[#6]([CX4!H0])-,:c2[cH]cccc12",*C1=C(C)c2[cH]cccc2N1* +1507,Tetrazole_hzide,"a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])[N!H0][N!H0][#6]2=,:[#7]-,:[#7]=,:[#7]-,:[#7]2[#6]",CN1N=NN=C1NNC(=O)C=C*1:*:*:*:*:*:1 +1508,Three-membered heterocycles (LS),[!#6!#1]1~*~*~1,*1~*~*~1 +1509,Three-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~1,*1~C~C~1 +1510,Saturated three-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-1,*1CC1 +1511,Unsaturated three-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1~[#6]=[#6]~1),$([!#1!#6]1=[#6]~[#6]~1)]",* +1512,Three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[#6]~1,*1~*~C~1 +1513,Saturated three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[#6]-1,*1*C1 +1514,Unsaturated three-membered heterocycles with two heteroatoms (LS),"[$([!#1!#6]1=[!#1!#6]~[#6]~1),$([!#1!#6]1~[!#6!#1]=[#6]~1)]",* +1515,Three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~1,*1~*~*~1 +1516,Saturated three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-1,*1**1 +1517,Unsaturated three-membered heterocycles with three heteroatoms (LS),[!#1!#6]1~[!#1!#6]=[!#1!#6]~1,*1~*=*~1 +1518,Three-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~1,*1~*~*~1 +1519,Three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6&R1]~[#6&R1]~1,*1~C~C~1 +1520,Saturated three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6&R1]-[#6&R1]-1,*1CC1 +1521,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1 +1522,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1 +1523,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1 +1524,Unsaturated three-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1~[#6R1]=[#6R1]~1),$([!#1!#6;R1]1=[#6R1]~[#6R1]~1)]",* +1525,Azirines (HS),"[$([#7R1]1-[#6R1]=[#6R1]-1),$([#7R1]1=[#6R1]-[#6R1]-1)]",* +1526,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1 +1527,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1 +1528,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1 +1529,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1 +1530,Three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~1,*1~*~C~1 +1531,Saturated three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-1,*1*C1 +1532,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1 +1533,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1 +1534,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1 +1535,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1 +1536,Unsaturated three-membered heterocycles with two heteroatoms (HS),"[$([!#1!#6;R1]1=[!#1!#6;R1]~[#6R1]~1),$([!#1!#6;R1]1~[!#6!#1;R1]=[#6R1]~1)]",* +1537,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1 +1538,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1 +1539,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1 +1540,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1 +1541,Three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~1 +1542,Saturated three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**1 +1543,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1 +1544,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1 +1545,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1 +1546,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1 +1547,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1 +1548,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1 +1549,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1 +1550,Unsaturated three-membered heterocycles with three heteroatoms (HS),[!#1!#6;R1]1-[!#6!#1;R1]=[!#6!#1;R1]1,*1*=*1 +1551,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1 +1552,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1 +1553,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1 +1554,Four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~1)]",* +1555,Saturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1-[!#6!#1]-[#6]-[#6]-1),$([!#6!#1]1-[#6]-[!#6!#1]-[#6]-1)]",* +1556,Unsaturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]=[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]=[#6]~1),$([!#6!#1]1=[#6]~[!#6!#1]~[#6]~1)]",* +1557,Four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~C~*~1 +1558,Saturated four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[#6]-1,*1*C*1 +1559,Unsaturated four-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]=[#6]~1)]",* +1560,Four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~1 +1561,Saturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1***1 +1562,Unsaturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*=*~1 +1563,Four-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~1 +1564,Four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~1 +1565,Saturated four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6R1]-[#6R1]-[#6R1]-1,*1CCC1 +1566,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1 +1567,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1 +1568,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1 +1569,Unsaturated four-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]=[#6R1]~[#6R1]~1)]",* +1570,Azetines (HS),"[$([#7R1]1=[#6R1]-[#6R1]-[#6R1]-1),$([#7R1]1-[#6R1]=[#6R1]-[#6R1]-1)]",* +1571,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1 +1572,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1 +1573,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1 +1574,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1 +1575,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1 +1576,Four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1577,Saturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-[#6R1]-1),$([!#6!#1;R1]1-[#6R1]-[!#6!#1;R1]-[#6R1]-1)]",* +1578,Diazetidines (HS),"[$([NR1]1[CR1][CR1][NR1]1),$([NR1]1[CR1][NR1][CR1]1)]",* +1579,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1 +1580,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1 +1581,Dioxetanes (HS),"[$([OR1]1[OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]1)]",* +1582,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1 +1583,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1 +1584,Dithietanes (HS),"[$([SX2R1]1[SX2R1][CR1][CR1]1),$([SX2R1]1[CR1][SX2R1][CR1]1)]",* +1585,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1 +1586,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1 +1587,Unsaturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]=[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]=[#6R1]~1),$([!#6!#1;R1]1=[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1588,Diazetines (HS),"[$([#7]1=,:[#7]-,:[#6]-,=,:[#6]-,:1),$([#7]1-,:[#7]=,:[#6]-,:[#6]-,=,:1),$([#7]1-,:[#7]-,:[#6]=,:[#6]-,=,:1),$([#7]1=,:[#6]-,:[#7]-,=,:[#6]-,:1)]",* +1589,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1 +1590,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1 +1591,Four-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~1,*1~C~C~C~1 +1592,Saturated four-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-[#6]-1,*1CCC1 +1593,Unsaturated four-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]=[#6]~[#6]~1)]",* +1594,Diazirenes (HS),"[$([#7R1]1-[#7R1]=[#6R1]-1),$([#7R1]1=[#7R1]-[#6R1]-1)]",* +1595,Four-membered heterocycles (LS),[!#6!#1]1~*~*~*~1,*1~*~*~*~1 +1596,Five-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~1,*1~*~*~*~*~1 +1597,Five-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~1 +1598,Saturated five-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCC1,*1CCCC1 +1599,Unsaturated five-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=CCCC1),$([!#6!#1]1C=CCC1),$([!#6!#1]1CC=CC1),$([!#6!#1]1=CC=CC1);!$(n1cccc1)]",* +1600,Aromatic five-membered heterocycles with one heteroatom (LS),[a!#6]1cccc1,*1cccc1 +1601,Five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1602,Saturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCC1),$([!#6!#1]1C[!#6!#1]CC1)]",* +1603,Unsaturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]C-,=CC1),$([!#6!#1]1[!#6!#1]=CCC1),$([!#6!#1]1[!#6!#1]C=CC1),$([!#6!#1]1=C[!#6!#1]-,=CC1),$([!#6!#1]1C[!#6!#1]CC=1),$([!#6!#1]1C[!#6!#1]C=C1)]",* +1604,Aromatic five-membered heterocycles with two heteroatoms (LS),"[$([a!#6]1[a!#6]ccc1),$([a!#6]1c[a!#6]cc1)]",* +1605,Five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1606,Saturated five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]C1)]",* +1607,Aromatic five-membered heterocycles with three heteroatoms (LS),"[$([a!#6]1[a!#6][a!#6]cc1),$([a!#6]1[a!#6]c[a!#6]c1)]",* +1608,Five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~1 +1609,Saturated five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]C1,*1**C*1 +1610,Unsaturated five-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1][!#6!#1]-,=[!#6!#1][#6]1),$([!#6!#1]1[!#6!#1]=[!#6!#1][!#6!#1][#6]1),$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1][#6]=1)]",* +1611,Aromatic five-membered heterocycles with four heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6]c1,*1:*:*c*:1 +1612,Five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~1 +1613,Saturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1****1 +1614,Unsaturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1=[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1**=**1 +1615,Aromatic five-membered heterocycles with five heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6][a!#6]1,*1:*:*:*:*:1 +1616,Five-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~1 +1617,Five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~1 +1618,Saturated five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1]1,*1CCCC1 +1619,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1 +1620,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1 +1621,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1 +1622,Unsaturated five-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1]=[CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1]=[CR1][CR1]1),$([!#6!#1;R1]1=[CR1][CR1]=[CR1][CR1]1);!$(n1cccc1)]",* +1623,Pyrrolines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1624,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1 +1625,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1 +1626,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1 +1627,Dihydrofurans (HS),"[$([OR1]1[CR1]=[CR1][CR1][CR1]1),$([OR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1628,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1 +1629,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1 +1630,Dihydrothiophenes (HS),"[$([SR1]1[CR1]=[CR1][CR1][CR1]1),$([SR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1631,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1 +1632,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1 +1633,Aromatic five-membered heterocycles with one heteroatom (HS),[a!#6;R1]1[cR1][cR1][cR1][cR1]1,*1cccc1 +1634,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1 +1635,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1 +1636,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1 +1637,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1 +1638,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1 +1639,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1 +1640,Five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1)]",* +1641,Saturated five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1]1)]",* +1642,Diazolidines (HS),"[$([NR1]1[NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1]1)]",* +1643,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1 +1644,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1 +1645,Dioxolanes (HS),"[$([OR1]1[OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1]1)]",* +1646,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1 +1647,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1 +1648,Dithiolanes (HS),"[$([SR1]1[SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1]1)]",* +1649,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1 +1650,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1 +1651,Pyrazolines (HS),"[$([NR1]1=[NR1][CR1][CR1][CR1]1),$([NR1]1[NR1]=[CR1][CR1][CR1]1),$([NR1]1[NR1][CR1]=[CR1][CR1]1)]",* +1652,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1 +1653,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1 +1654,Imidazolines (HS),"[$([NR1]1=[CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1]=[CR1][CR1]1),$([NR1]1[CR1][NR1][CR1]=[CR1]1)]",* +1655,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1 +1656,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1 +1657,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1 +1658,Dioxolenes (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]=[CR1]1)]",* +1659,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1 +1660,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1 +1661,Dithiolenes (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]1),$([SR1]1[CR1][SR1][CR1]=[CR1]1)]",* +1662,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1 +1663,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1 +1664,Aromatic five-membered heterocycles with two heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][cR1][cR1][cR1]1),$([a!#6;R1]1[cR1][a!#6;R1][cR1][cR1]1)]",* +1665,Diazoles (HS),"[$([nR1]1[nR1][cR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][cR1]1)]",* +1666,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1 +1667,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1 +1668,Oxazoles (HS),"[$([oR1]1[nR1][cR1][cR1][cR1]1),$([oR1]1[cR1][nR1][cR1][cR1]1)]",* +1669,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1 +1670,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1 +1671,Thiazoles (HS),"[$([sR1]1[nR1][cR1][cR1][cR1]1),$([sR1]1[cR1][nR1][cR1][cR1]1)]",* +1672,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1 +1673,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1 +1674,Five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1675,Saturated five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1676,Triazolidines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1]1)]",* +1677,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1 +1678,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1 +1679,Trioxolanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1]1)]",* +1680,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1 +1681,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1 +1682,Trithiolanes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1]1)]",* +1683,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1 +1684,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1 +1685,"1,2,3-Triazolines (HS)","[$([NR1]1=[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][NR1][CR1][CR1]=1),$([NR1]1[NR1][NR1][CR1]=[CR1]1)]",* +1686,"1,2,4-Triazolines (HS)","[$([NR1]1=[NR1][CR1][NR1][CR1]1),$([NR1]1[NR1]=[CR1][NR1][CR1]1),$([NR1]1[NR1][CR1]=[NR1][CR1]1)]",* +1687,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1 +1688,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1 +1689,Aromatic five-membered heterocycles with three heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][a!#6;R1][cR1][cR1]1),$([a!#6;R1]1[a!#6;R1][cR1][a!#6;R1][cR1]1)]",* +1690,Triazoles (HS),"[$([nR1]1[nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1]1)]",* +1691,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1 +1692,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1 +1693,Oxadiazoles (HS),"[$([oR1]1[nR1][nR1][cR1][cR1]1),$([oR1]1[nR1][cR1][nR1][cR1]1),$([oR1]1[nR1][cR1][cR1][nR1]1),$([oR1]1[cR1][nR1][nR1][cR1]1)]",* +1694,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1 +1695,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1 +1696,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1 +1697,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1 +1698,Five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~1 +1699,Saturated five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1][CR1]1,*1**C*1 +1700,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1 +1701,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1 +1702,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1 +1703,Unsaturated five-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1][!#6!#1;R1]-,=[!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1]=[!#6!#1;R1][!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][#6R1]=1)]",* +1704,Aromatic five-membered heterocycles with four heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][cR1]1,*1:*:*c*:1 +1705,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1 +1706,Oxatriazoles (HS),"[$([oR1]1[nR1][nR1][nR1][cR1]1),$([oR1]1[nR1][nR1][cR1][nR1]1)]",* +1707,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1 +1708,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1 +1709,Thiatriazoles (HS),"[$([sR1]1[nR1][nR1][nR1][cR1]1),$([sR1]1[nR1][nR1][cR1][nR1]1)]",* +1710,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1 +1711,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1 +1712,Five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~1 +1713,Saturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1****1 +1714,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1 +1715,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1 +1716,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1 +1717,Unsaturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1=[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**=**1 +1718,Aromatic five-membered heterocycles with five heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][a!#6;R1]1,*1:*:*:*:*:1 +1719,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1 +1720,Six-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~*~1,*1~*~*~*~*~*~1 +1721,Six-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~C~1 +1722,Saturated six-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCCC1,*1CCCCC1 +1723,Unsaturated six-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1=C~C~C~C~C~1),$([!#1!#6]1~C=C~C~C~C~1),$([!#1!#6]1~C~C=C~C~C~1);!$([a!c]1ccccc1)]",* +1724,Aromatic six-membered heterocycles with one heteroatom (LS),[a!c]1ccccc1,*1ccccc1 +1725,Six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1726,Saturated six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCCC1),$([!#6!#1]1C[!#6!#1]CCC1),$([!#6!#1]1CC[!#6!#1]CC1)]",* +1727,Aromatic six-membered heterocycles with two heteroatoms (LS),"[$([a!c]1[a!c]cccc1),$([a!c]1c[a!c]ccc1),$([a!c]1cc[a!c]cc1)]",* +1728,Six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1729,Saturated six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CCC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]CC1),$([!#6!#1]1C[!#6!#1]C[!#6!#1]C1)]",* +1730,Aromatic six-membered heterocycles with three heteroatoms (LS),"[$([a!c]1[a!c][a!c]ccc1),$([a!c]1[a!c]c[a!c]cc1),$([a!c]1c[a!c]c[a!c]c1)]",* +1731,Six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[!#6!#1]~[#6]~1)]",* +1732,Saturated six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1][!#6!#1]C[!#6!#1]C1),$([!#6!#1]1[!#6!#1]C[!#6!#1][!#6!#1]C1)]",* +1733,Aromatic six-membered heterocycles with four heteroatoms (LS),"[$([a!c]1[a!c][a!c][a!c]cc1),$([a!c]1[a!c][a!c]c[a!c]c1),$([a!c]1[a!c]c[a!c][a!c]c1)]",* +1734,Six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~*~1 +1735,Saturated six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-C-1,*1**C**1 +1736,Aromatic six-membered heterocycles with five heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c]c1,*1:*:*c*:*:1 +1737,Saturated six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1*****1 +1738,Unsaturated six-membered heterocycles with six heteroatoms (LS),[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1739,Aromatic six-membered heterocycles with six heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c][a!c]1,*1:*:*:*:*:*:1 +1740,Six-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~*~1 +1741,Six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~C~1 +1742,Saturated six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1][CR1]1,*1CCCCC1 +1743,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1 +1744,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1 +1745,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1 +1746,Unsaturated six-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1=[CR1]~[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]=[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]~[CR1]=[CR1]~[CR1]~[CR1]~1);!$([a!c]1ccccc1)]",* +1747,Tetrahydropyridines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1][CR1]1)]",* +1748,Dihydropyridines (HS),"[$([NR1]1=[CR1][CR1]-,=[CR1]-,=[CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]-,=[CR1]-,=1),$([NR1]1[CR1]=[CR1][CR1]=[CR1][CR1]1)]",* +1749,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1 +1750,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1 +1751,Aromatic six-membered heterocycles with one heteroatom (HS),[a!c;R1]1[cR1][cR1][cR1][cR1][cR1]1,*1ccccc1 +1752,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1 +1753,Six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~1)]",* +1754,Saturated six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1][!#6!#1;R1][CR1][CR1]1)]",* +1755,Hexahydrodiazines,"[$([NR1]1[NR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1][NR1][CR1][CR1]1)]",* +1756,Dioxanes,"[$([OR1]1[OR1][CR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][CR1][OR1][CR1][CR1]1)]",* +1757,Dithianes,"[$([SR1]1[SR1][CR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][CR1][SR1][CR1][CR1]1)]",* +1758,Dioxines (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]=[CR1]1),$([OR1]1[CR1]=[CR1][OR1][CR1]=[CR1]1)]",* +1759,Aromatic six-membered heterocycles with two heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][cR1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][cR1][a!c;R1][cR1][cR1]1)]",* +1760,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1 +1761,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1 +1762,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1 +1763,Six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1764,Saturated six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1765,Hexahydrotriazines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][NR1][CR1]1)]",* +1766,Trioxanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][OR1][CR1]1)]",* +1767,Trithianes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][SR1][CR1]1)]",* +1768,Aromatic six-membered heterocycles with three heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][a!c;R1][cR1]1)]",* +1769,Triazines (HS),"[$([nR1]1[nR1][nR1][cR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][nR1][cR1]1)]",* +1770,Saturated six-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][!#6!#1;R1][CR1]1)]",* +1771,Hexahydrotetrazines (HS),"[$([NR1]1[NR1][NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][NR1][CR1]1),$([NR1]1[NR1][NR1][CR1][NR1][CR1]1)]",* +1772,Tetroxanes (HS),"[$([OR1]1[OR1][OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][OR1][CR1]1)]",* +1773,Tetrathianes (HS),"[$([SR1]1[SR1][SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][SR1][CR1]1)]",* +1774,Aromatic six-membered heterocycles with four heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][a!c;R1][cR1][a!c;R1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][a!c;R1][cR1]1)]",* +1775,Tetrazines (HS),"[$([nR1]1[nR1][nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][nR1][cR1][nR1][cR1]1),$([nR1]1[nR1][cR1][nR1][nR1][cR1]1)]",* +1776,Six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~*~1 +1777,Saturated six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[CR1]-1,*1**C**1 +1778,Aromatic six-membered heterocycles with five heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][cR1]1,*1:*:*c*:*:1 +1779,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1 +1780,Six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~*~1 +1781,Saturated six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1*****1 +1782,Unsaturated six-membered heterocycles with six heteroatoms (HS),[$([!#6!#1;R1]1=[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1783,Aromatic six-membered heterocycles with six heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][a!c;R1]1,*1:*:*:*:*:*:1 +1784,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1 +1785,Six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~*~1 +1786,Dithiines (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]=[CR1]1),$([SR1]1[CR1]=[CR1][SR1][CR1]=[CR1]1)]",* +1787,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1 +1788,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1 +1789,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1 +1790,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C +1791,Allyl halides,"[CX3]=[CX3][CX4][F,Cl,Br,I]",*CC=C +1792,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF +1793,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl +1794,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr +1795,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI +1796,Vinyl fluorides,F[CX3]=[CX3],C=CF +1797,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl +1798,Vinyl bromides,Br[CX3]=[CX3],C=CBr +1799,Vinyl iodides,I[CX3]=[CX3],C=CI +1800,Alkynyl fluorides,F[CX2]#[CX2],C#CF +1801,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl +1802,Alkynyl iodides,I[CX2]#[CX2],C#CI +1803,Alkynyl bromides,Br[CX2]#[CX2],C#CBr +1804,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC +1805,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc +1806,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc +1807,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH] +1808,"1,3 – Diphenols",c([OH1])[aR1]c([OH1]),[OH]c*c[OH] +1809,"1,4 - Diphenols",c1([OH1])aac([OH1])aa1,[OH]c1*:*c([OH])*:*1 +1810,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH] +1811,"1,3 – Dithiophenols",c([SH1])[aR1]c([SH1]),[SH]c*c[SH] +1812,"1,4 – Dithiophenols",c1([SH1])aac([SH1])aa1,[SH]c1*:*c([SH])*:*1 +1813,"1,2 – Aminophenols","c([OH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[OH] +1814,"1,3 – Aminophenols","c([OH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[OH] +1815,"1,4 – Aminophenols","c1([OH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([OH])*:*1 +1816,"1,2 – Aminothiophenols","c([SH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[SH] +1817,"1,3 – Aminothiophenols","c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[SH] +1818,"1,4 – Aminothiophenols","c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([SH])*:*1 +1819,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C +1820,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C +1821,Carbonic acid esters,"[#1,#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*OC(=O)OC +1822,Phosphonic acid amides,[OX1]=[Pv5X4]([NX3])([#6])[!#6!$([SX2])],*P(C)(N)=O +1823,Aldehyde,[CX3H1](=O)[#6],C[CH]=O +1824,AliphaticEther,[!$(C=O);$([C&!a])][OX2&H0][!$(C=O);$([C&!a])],*O* +1825,AminoAcids,"[$([NX3,NX4+][CX4H]([*])[CX3](=[OX1])[O,N]),$([$([$([NX3H2,NX4H3+]),$([NX3H](C)(C))][CX4H2][CX3](=[OX1])[OX2H,OX1-,N])])]",* +1826,AromaticHalogen,"[$([a][F,Cl,I])]",* +1827,AromaticNGroups,"[$([a]N(~O)~O),$([a]N([#1])[*]),$([a]N([#1])[!#1])]",* +1828,AromaticSulphonicAcid,"[$([#16X4](=[OX1])(=[OX1])([a])[OX2H,OX1H0-]),$([#16X4+2]([OX1-])([OX1-])([a])[OX2H,OX1H0-])]",* +1829,AzoGroup,[$([!R&N]=[!R&N])],* +1830,CyanoGroupOnMoreThanEightAtomsChain,[N]#[C]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0],*~*~*~*~*~*~*~*~C#N +1831,Epoxide,[$(C1OC1)],* +1832,Esters,[#6][CX3](=O)[$([OX2H0]([#6])[#6])],*C(C)=O +1833,Formaldehyde,[CX3H2](=O),C=O +1834,Ketone,[C][C](=O)[C],CC(C)=O +1835,MoreThanTwoHydroxyOnAromaticRing,"[$([a&R]([OX2H])[a&R]([OX2H])),$([a&R]([OX2H])a[a&R]([OX2H])),$([a&R]([OX2H])aa[a&R]([OX2H]))]",* +1836,Nitrile,[C]#[N],C#N +1837,NNitroso,[$(NN=O)],* +1838,PyridineRing,[$(n1ccccc1)],* +1839,TerminalTertButyl,[$([C]([CH3])([CH3])([CH3])([*]))],* +1840,TertiaryAmine,[!R&NX3&H0],* +1841,TriazineRing,"[$(n1nnccc1),$(n1ncncc1),$(n1cncnc1)]",* +1842,Trifluoromethyl,[$([*]C(F)(F)F)],* +1843,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1 +1844,Phenoxazines,"[OX1,N]=[#6]1-,:[#6]=,:[#6]2-,:[#16X2,#8X2]-,:[#6]3=,:[#6]-,:[#6](=,:[#6]-,:[#6]=,:[#6]3-,:[#7]=,:[#6]2-,:[#6]=,:[#6]1)",*=C1C=CC2=NC3=CC=CC=C3*C2=C1 +1845,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1 +1846,Imidazotriazoles,"[c,n]1cnn2c([NH])cnc12",[NH]c1cnc2*cnn12 +1847,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21 +1848,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21 +1849,NCCN,"[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]-[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]",** +1850,Picolylamines_A,"[$([NX3][CH2]c1ncnc([NX3])c1),$([NX3][CH2]c1nccc([NX3])n1)]",* +1851,Picolylamines_B,"[$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]n([H,CH3])cc1),$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]ccn1[H,CH3])]",* +1852,Picolylamines_C,"c1cccnc1[CH2!R][NX3!R]([H,CH3])[CH2!R]",*N([CH2])[CH2]c1ccccn1 +1853,Bis-picolylamines,"[nv3X2]c([c,s,n])[CX4][NX3]([H,C])[CX4]c([c,s,n])[nv3X2,nv3X3H1]",*N(Cc(*)*)Cc(*)n +1854,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1 +1855,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1 +1856,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n +1857,Diarylmethanes,"[$(c1[nX2][c,n][c,n][c,n]1),$([cr6][nX2r6])][CX4H2!R][$(c2[nX2][c,n][c,n][c,n]2),$([cr6][nX2r6])]",*[CH2]* +1858,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12 +1859,Heterylamides_A,"[$([cr5][n,s;r5][n,o;r5]),$([cr5]([nr5])[s,o,n;r5])][Nv3X3H1!R][CX3!R](=[OX1])[$([cr5][nv3X2r5]),$(c1ncccc1),$(c1c([OX2][CH3])cccc1)]",*[NH]C(*)=O +1860,Heterylamides_B,"[$(c1nnc[o,n]1),$(c1nccs1)][Nv3X3H!R][C!R](=[OX1])[CX4!H0]([H,CX4])[SX2,n]cc",*[NH]C(=O)C(*)*cc +1861,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1 +1862,8-Quinolinols,"[H,C][OX2]c1c([CX4][NX3])ccc2cccnc21",*Oc1c(CN)ccc2cccnc12 +1863,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1 +1864,Perchloroquinone,"[OX1]=[CX3]1C([F,Cl,Br,I])=C([F,Cl,Br,I])[CX3](=[OX1])C([F,Cl,Br,I])=C1[F,Cl,Br,I]",*C1=C(*)C(=O)C(*)=C(*)C1=O +1865,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn +1866,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1 +1867,A3,"[OH][CX3](=[OX1])[#6]1-,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:1",O=C([OH])C1=CC=CC=*1 +1868,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1 +1869,B5,"[#6]1=,:[#6]-,:[#6]=,:[#6]([OH])-,:[#6]2=,:[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]2",[OH]C1=CC=CC2=C1*=CC=C2 +1870,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12 +1871,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12 +1872,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12 +1873,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1 +1874,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1 +1875,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1 +1876,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1 +1877,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1 +1878,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1 +1879,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1 +1880,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12 +1881,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12 +1882,"C10, C11","[CH3]c1nc([OH])cc([OH,CH3])n1",*c1cc([OH])nc([CH3])n1 +1883,"C10*, C11*","[CX4]c1nc([OH])cc([OH,CX4])n1",*c1cc([OH])nc(C)n1 +1884,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH] +1885,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S +1886,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH] +1887,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH] +1888,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S +1889,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C +1890,"E6, E8","O=[#6]1-,:[#7]([H,CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",*N1C=CC=C([OH])C1=O +1891,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH] +1892,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C +1893,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S +1894,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S +1895,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH] +1896,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH] +1897,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH] +1898,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH] +1899,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1 +1900,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1 +1901,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1 +1902,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1 +1903,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1 +1904,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1 +1905,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21 +1906,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1 +1907,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12 +1908,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH] +1909,"G9,G10","c1ccc(c(c1)[OH,SH])[OX2][CX4]",*c1ccccc1OC +1910,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH] +1911,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH] +1912,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH] +1913,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH] +1914,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH] +1915,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1 +1916,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1 +1917,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1 +1918,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1 +1919,H8 - H12,"C[CX3](=[OX1])[CX4!H0]([H,CX4,Cl])[CX3](=[OX1])C",*C(C(C)=O)C(C)=O +1920,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O +1921,Salts_C,"[!#1!#2!#5!#6!#7!#8!#9!#10!#14!#15!#16!#17!#18!#32!#33!#34!#35!#36!#51!#52!#53!#54!#84!#85!#86]~[#6,#7,#8,#16]",*~* +1922,Pt,[Pt],[Pt] +1923,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +1924,β-lactones and γ- sultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +1925,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O +1926,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +1927,Heterocyclic Polycyclic Aromatic Hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +1928,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1929,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1 +1930,Azafluorenones,"[OX1,SX1]=[#6X3]1c2c([nX2][cX3,nX2,nX3][cX3,nX2,nX3][cX3,nX2,nX3]2)[c,n]2c1[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])]2",*=C1c2cccc*2c2n*:*:*c21 +1931,Cyanothioazinones,"[SX1]=[#6X3]1-,:[#7X3H1]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#7X2,#6X3!$([#6X3]=[A])]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#6X3]1([CX2]#[NX1])",N#CC1=**=*[NH]C1=S +1932,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1 +1933,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1934,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1 +1935,Benzoxathiolones,"[$([#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]),$([#8]1-,:[#6](-,:[#16]c4ccc(cc14)[#7,#8])=[OX1,SX1])]",* +1936,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21 +1937,Pyrazolones,"[#7X2]1=,:[#6X3]-,:[#6X3](-,:[#6X3](-,:[#7X3]1)=[SX1,OX1])=,:[#6X3H1](-,:[#7X3H1])",*=C1NN=CC1=[CH][NH] +1938,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1 +1939,Pyrimidinones_A,"[OX1,SX1]=[#6X3]1[#7X3](-,:[#7X2]=,:[#6X3][NX3H1][#6])-,:[cX3!$([#6X3]=[A])]=,:[#7X2]-,:[cX3!$([#6X3]=[A])]=,:[cX3!$([#6X3]=[A])]1",*=C1c=cN=cN1N=C[NH]C +1940,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12 +1941,Pyrimidinones_C,"[OX1,SX1]=[#6X3]1[#7X3]-,:[#6X3!$([#6X3]=[A])](-[NX3])=,:[#7X2]-,:[#6X3]2([nX2][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])]c12)",*=C1NC(N)=NC2nCCCc21 +1942,Pyrimidinodiones,"[#6X3]1(=[OX1,SX1])-,:[#7X3H1]-,:[#6X3](=[OX1,SX1])-,:[#7X3,#7X2]~[#6X3]([#7X2,#7X3;R1])-,:[#6X3]1[sX2r5R1,nX2r5R1,$([nx2r6R1]([cX3])[cX3])]",*C1C(*)C(=*)[NH]C(=*)*~1 +1943,Thienopyrimidinone_A,"[OX1,SX1]=[#6X3]1-,:[#7X3H1]-,:[#6X4]-,:[#7X3H1]-,:[#6]2-,:[#16X2,#8X2]-,:[#6]3[CX4][NX3,CX4][CX4][CX4]-,:[#6]3-,:[#6]12",*=C1[NH]C[NH]C2*C3C*CCC3C21 +1944,Piperazinediones,"[#7X3]1-,:[#6X3](=[OX1,SX1])-,:[#6X3](=[OX1,SX1])-,:[NX3]-,:[#6X3]2[cX3!$([#6X3]=[A])][cX3]([NX3H1][CX3]=[OX1])[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3]12",*=C1NC2cc([NH]C=O)ccc2NC1=* +1945,4-Heteryl-thiazoles,"s1[c,nX2][c,nX2](-c(c)[nX2,nX3,sX2])[nX2]c1",*c(c)-*1:*scn1 +1946,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1 +1947,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH] +1948,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1 +1949,Cyanothioethers,"[NX1]#[CX2][CX4H2][SX2]c1n[c,n][c,n][c,n]n1",N#C[CH2]Sc1n*:*:*n1 +1950,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1 +1951,Fused azacycles_A,"[nX2R1][c,n;R2]1[c,n;R2]([c,n;R1])[c,n][c,n][c,n;R2]([c,n;R1])[nR2]1[nX2R1]",*:*1:*:*:*(:*)n(n)*:1n +1952,Fused azacycles_B,"[NX1]#[CX2]c1[c!$([#6]=[OX1])]n[n,c!$([#6]=[OX1])]2[c,n][c!$([#6]=[OX1])][c!$([#6]=[OX1])]nc12",N#Cc1cn*2:*ccnc21 +1953,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12 +1954,Arylethanolamines,"[$([NX3]([CX4,H])([CX4,H])[CX4]),$([OX2]([H,CX4])[CX4])][CX4!H0][CX4H2][NX3H1]c[nX2r6R1][nX2,nX3][nX2,cX3;R1][cX3,nX2][cX3,nX2][sX2,cX3][cX3]",*C[CH2][NH]cn*:*:*:*:*c +1955,Azaspironones,"[X4;R2]12(-,:;@[#6X3]-,:;@[#6X3]-,:;@[#7X3]-,:;@[#6X3]-,:;@1)-,:;@[#16X2]-,:;@[#6X3]=,:;@[#7X2]-,:;@[#7X3]-,:;@2",C1C*2(CN1)NN=CS2 +1956,Radical,[#16;X3v3+0],S +1957,N⋯X halogen bonding,"N[F,Cl,Br,I]",*N +1958,Charged atoms,"[+,-]",* +1959,Benzyl Imidazole scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*-,=*c:3:c:c:c:c:c:3",*(*c1ccccc1)*1:*:*2:*c*c*:2:*:1 +1960,6-Phenyl Napthaline type scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s][c,n,o,s]2)*~*c:3:c:c:c:c:c:3",*(~*c1ccccc1)*1:*:*:*2:*c*c*:2:*:1 +1961,2-(2-(1H-pyrrol-2-yl)ethyl)-1H-benzoimidazole scaffold,"[c,n]:1:c:c2:c(:[c,n]:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*~*c3ccc*3",*(~*c1ccc*1)*1:*c2*c*cc2*:1 +1962,2 - Olefin group,"[$([CX3H2]=[CX3H1]),$([CX3H1]=[CX3H1]),$([CX3H2]=[CX3H0]),$([CX3H1]=[CX3H0]),$([CX3H0]=[CX3H0])]",* +1963,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +1964,6 - Methanol,[CX4H3][OX2H1],[CH3][OH] +1965,7 - Water,[OX2H2],O +1966,9 - Сarbonyl,"[$([CX4H3][CX3](=[OX1])[#6]),$([CX4H2][CX3H0](=[OX1])[#6])]",* +1967,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O +1968,11 - Acetate group,"[$([CX4H3][CX3](=[OX1])[OX2][#6]),$([CX4H2][CX3](=[OX1])[OX2][#6])]",* +1969,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +1970,14 - Primary amine,"[$([CX4H3][NX3H2]),$([CX4H2][NX3H2]),$([CX4H1][NX3H2])]",* +1971,16 - Tertiary amine,"[$([CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]),$([CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6])]",* +1972,19 - CCN,"[$([CX4H3][CX2]#[NX1]),$([CX4H2][CX2]#[NX1])]",* +1973,20 - COOH,"[$([CX3H0](=[OX1])[OX2H1]),$([CX3H1](=[OX1])[OX2H1])]",* +1974,21 - CCl,"[$([CX4H2!$([CX4H2](Cl)Cl)]Cl),$([CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl]),$([CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl])]",* +1975,22 - CCl2,"[$([CX4H2]([Cl])[Cl]),$([CX4H1]([!Cl!F])([Cl])[Cl]),$([CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F])]",* +1976,23 - CCl3,"[$([CX4H1]([Cl])([Cl])[Cl]),$([CX4H0]([!Cl!F])([Cl])([Cl])[Cl])]",* +1977,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +1978,26 - CNO2,"[$([CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)])]",* +1979,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S +1980,29 - CH3SH,"[$([CX4H3][SX2H1]),$([CX4H2][SX2H1])]",* +1981,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +1982,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +1983,32 - Iodo compounds,[I],I +1984,33 - Bromo compounds,[Br!$([Br][cR])],Br +1985,34 - Carbon triple bond,"[$([CX2H1]#[CX2H0]),$([CX2H0]#[CX2H0])]",* +1986,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +1987,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +1988,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl +1989,39 - DMF,"[$([CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3]),$([CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2])]",* +1990,40 - CF2,"[$([CX4](F)(F)(F)[!Cl!F]),$([CX4](F)(F)([!F!Cl!H])([!F!Cl!H])),$([CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]))]",* +1991,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +1992,42 - SiH2,"[$([SiX4H3]),$([SiX4H2]([!$([OX2])])([!$([OX2])])),$([SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])])),$([SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]))]",* +1993,43 - SiO,"[$([SiX4H2][OX2]),$([SiX4H1][OX2]),$([SiX4H0][OX2])]",* +1994,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +1995,47 - OCCOH,"[$([OX2H0!R][CX4H2][CX4H2][OX2H1]),$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +1996,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +1997,52 - Sulphones,"[$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2]),$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1])]",* +1998,53 - Oxides,"[$([CX4H2]1[OX2][CX4H2]1),$([CX4H2]1[OX2][CX4H1]1),$([CX4H2]1[OX2][CX4H0]1),$([CX4H1]1[OX2][CX4H1]1),$([CX4H1]1[OX2][CX4H0]1),$([CX4H0]1[OX2][CX4H0]1)]",* +1999,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2000,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C +2001,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH] +2002,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C +2003,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C +2004,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C +2005,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c +2006,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +2007,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH] +2008,17 - H2O (7 - Water),[OX2H2],O +2009,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O +2010,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O +2011,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O +2012,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O +2013,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O +2014,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +2015,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3] +2016,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2] +2017,28 - THF (13 - Ether),[OX2R!r3!$([OX2]C=[OX1])!$([OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1)]([R])[CX4H2R],*O[CH2] +2018,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2] +2019,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2] +2020,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2] +2021,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3] +2022,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2] +2023,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH] +2024,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3] +2025,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2] +2026,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1 +2027,39 - C5H4N (18 - Pyridine),"[$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]:[cX3H1]1)]",* +2028,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N +2029,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N +2030,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH] +2031,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH] +2032,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl +2033,46 - CHCl (21 - CCl),[CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl],*[CH](*)Cl +2034,47 - CCl (21 - CCl),[CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl],*C(*)(*)Cl +2035,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl +2036,49 - CHCl2 (22 - CCl2),[CX4H1]([!Cl!F])([Cl])[Cl],*[CH](Cl)Cl +2037,50 - CCl2 (22 - CCl2),[CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F],*C(*)(Cl)Cl +2038,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl +2039,52 - CCl3 (23 - CCl3),[CX4H0]([!Cl!F])([Cl])([Cl])[Cl],*C(Cl)(Cl)Cl +2040,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +2041,55 - CH3NO2 (26 - CNO2),"[CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH3] +2042,56 - CH2NO2 (26 - CNO2),"[CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH2] +2043,57 - CHNO2 (26 - CNO2),"[CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH] +2044,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S +2045,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH] +2046,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH] +2047,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +2048,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +2049,64 - I (32 - Iodo compounds),[I],I +2050,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br +2051,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C +2052,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C +2053,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +2054,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +2055,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl +2056,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O +2057,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O +2058,74 - CF3 (40 - CF2),[CX4](F)(F)(F)[!Cl!F],*C(F)(F)F +2059,75 - CF2 (40 - CF2),[CX4](F)(F)([!F!Cl!H])([!F!Cl!H]),*C(*)(F)F +2060,76 - CF (40 - CF2),[CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]),*C(*)(*)F +2061,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +2062,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3] +2063,79 - SiH2 (42 - SiH2),[SiX4H2]([!$([OX2])])([!$([OX2])]),*[SiH2]* +2064,80 - SiH (42 - SiH2),[SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[SiH](*)* +2065,81 - Si (42 - SiH2),[SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[Si](*)(*)* +2066,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2] +2067,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH] +2068,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si] +2069,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +2070,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl +2071,87 - CCl2F (45 - CClF),[CX4H0]([Cl])([Cl])([F])[!Cl!F],*C(F)(Cl)Cl +2072,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl +2073,89 - HCClF (45 - CClF),[CX4H1](Cl)(F)([!F!Cl]),*[CH](F)Cl +2074,90 - CClF2 (45 - CClF),[CX4H0](Cl)(F)(F)[!Cl!F],*C(F)(F)Cl +2075,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl +2076,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl +2077,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl +2078,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O +2079,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O +2080,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O +2081,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O +2082,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O +2083,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O +2084,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH] +2085,101 - C2H4O2 (47 - OCCOH),"[$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +2086,102 - CH3S (48 - CH2S),[CX4H3][SX2H0][*],*S[CH3] +2087,103 - CH2S (48 - CH2S),[CX4H2][SX2H0!$([SX2H0]([CX4H2])[CX4H3])][*],*S[CH2] +2088,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +2089,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1 +2090,107 - C4H3S (50 - Thiophene),"[$([#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H0]=,:1),$([#6X3H1]1-,:[#16X2]-,:[#6X3H0]=,:[#6X3H1]-,:[#6X3H1]=,:1)]",* +2091,109 - NCO (51 - NCO),[*][NX2]=[CX2]=[OX1],*N=C=O +2092,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O +2093,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O +2094,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1 +2095,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1 +2096,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1 +2097,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1 +2098,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1 +2099,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1 +2100,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2101,phosphorodithionate,[$([SX2H0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2102,"O,O-diethylphosphorodithionate",CCOP(=S)(OCC)SC([*:1]),CCOP(=S)(OCC)SC[*:1] +2103,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O +2104,"O,O-dimethylphosphoryl",COP(=O)(O([*:1]))OC,COP(=O)(OC)O[*:1] +2105,phosphorothionate,[$([OH0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2106,diethylphosphorothionate,CCOP(=S)(O([*:1]))OCC,CCOP(=S)(OCC)O[*:1] +2107,O-phenyl phenylphosphonothioate,S=P(O([*:1]))(Oc1ccc([*:1])cc1)c1ccccc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])c1ccccc1 +2108,O-phenyl phosphonothioate,S=P(O([*:1]))(O([*:1]))Oc1ccc([*:1])cc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])O[*:1] +2109,carbamate,[$(N([!H])C(=O)[OH0])]C(=O)[OH0],*C(O)=O +2110,"2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-(aminosulfanyl)-N-methylcarbamate",CN(SN([*:1])([*:1]))C(=O)Oc1cccc2CC(C)(C)Oc12,CN(SN([*:1])[*:1])C(=O)Oc1cccc2c1OC(C)(C)C2 +2111,methyl(propoxysulfanyl) carbamate,CN(SOCCC([*:1]))C(=O)O([*:1]),CN(SOCCC[*:1])C(=O)O[*:1] +2112,phenyl carbamate,O=C(N([*:1]))Oc1ccccc([*:1])1,O=C(N[*:1])Oc1ccccc1[*:1] +2113,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C +2114,dimethylcarbamate,CN(C)C(=O)O([*:1]),CN(C)C(=O)O[*:1] +2115,barbiturates,*C1(*)[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]1=O,*C1(*)C(=O)NC(=O)NC1=O +2116,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1 +2117,Phenothiazine,*-[#7]-1-c2ccccc2-[#16]-c2ccccc-12,*N1c2ccccc2Sc2ccccc21 +2118,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1 +2119,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1 +2120,"2,4-dichloro-benzene-1,3-dicarbonitrile",N#Cc1c([*:1])c([*:1])c(Cl)c(C#N)c1Cl,N#Cc1c(Cl)c(C#N)c([*:1])c([*:1])c1Cl +2121,R1 - Reactive alkyl halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2122,R2 - Acid halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2123,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O +2124,R4 - Sulphate esters,"COS(=O)O[C,c]",*OS(=O)OC +2125,R5 - Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2126,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O +2127,R7 - Peroxides,OO,OO +2128,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2129,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1 +2130,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O +2131,R11 - Isocyanates & Isothiocyanantes,"N=C=[S,O]",*=C=N +2132,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2133,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S +2134,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2135,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-] +2136,R16 - beta carbonyl quaternary Nitrogen,"C(=O)C[N+,n+]",*CC=O +2137,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O +2138,"R18 - Quaternary C,Cl,I,P or S","[C+,Cl+,I+,P+,S+]",* +2139,R19 - Phosphoranes,C=P,C=P +2140,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl +2141,R21 - Nitroso,[N&D2](=O),N=O +2142,R22 - P/S Halides,"[P,S][Cl,Br,F,I]",** +2143,R23 - Carbodiumide,N=C=N,N=C=N +2144,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+] +2145,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2146,R26 - Cyanohydrins,N#CC[OH],N#CC[OH] +2147,R27 - Acyl cyanides,N#CC(=O),N#CC=O +2148,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O +2149,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2150,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N +2151,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2152,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC +2153,I2 - Compounds with 4 or more acidic groups,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2154,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2155,I4 - Disulphides,SS,SS +2156,I5 - Thiols,[SH],[SH] +2157,"I6 - Epoxides, Thioepoxides, Aziridines","C1[O,S,N]C1",*1CC1 +2158,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2159,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2160,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2161,I10 - Thiocyanate,SC#N,N#CS +2162,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+] +2163,I12 - Thioesters,"C[O,S;R0][C;R0](=S)",C*C=S +2164,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N +2165,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1 +2166,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2167,I16 - Betalactams,N1CCC1=O,O=C1CCN1 +2168,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1 +2169,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2170,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2171,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2172,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2173,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2174,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1 +2175,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2176,"A1 - e.g., carboxylic acid","[OH1][P,C,S](=O)",O=*[OH] +2177,"A2 - e.g.,imide","[NH1]([P,S]=O)([P,S]=O)",O=*[NH]*=O +2178,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1 +2179,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1 +2180,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1 +2181,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O +2182,A8,[nH1]1ncoc1=O,O=c1[nH]nco1 +2183,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1 +2184,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1 +2185,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1 +2186,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1 +2187,A13,[nH1]1occc1=O,O=c1cco[nH]1 +2188,A14,[OH1]c1oncc1,[OH]c1ccno1 +2189,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1 +2190,A16 - tetrazole,[nH1]nnn,nnn[nH] +2191,A17,[nH1](n)nn,nn[nH]n +2192,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1 +2193,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1 +2194,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1 +2195,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1 +2196,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1 +2197,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1 +2198,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1 +2199,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21 +2200,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21 +2201,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21 +2202,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH] +2203,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1 +2204,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH] +2205,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F +2206,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O +2207,A33 - phenol,"[OH1]c1c[c,n]ccc1",[OH]c1c*ccc1 +2208,B1 - primary amine,[NH2][CX4],C[NH2] +2209,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C +2210,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C +2211,B4SUB,"[C,c](=N)N",N*=N +2212,B5EXC,"[C,c](=N)N[C,S](=O)",N=*N*=O +2213,B6,"[$([C,c](=N)N);!$([C,c](=N)N[C,S](=O))]",* +2214,B7EXC,n(:c)(:c):a,*n(c)c +2215,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1 +2216,B8EXC,"[N,n;+1]",* +2217,B9,"[$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]",* +2218,E1 - alkyl and aryl ketones and aldehydes,"[C;H1](=[O,S])[C,c]",*C=* +2219,"E2 - e.g., carboxylic esters","[C,P;H1](=[O,S])[O,S]",**=* +2220,"E3 - e.g., carbonates","[C](=O)([C,c,O,S])[C,c,O,S]",*C(*)=O +2221,E4EXC,C(=O)[OH1],O=C[OH] +2222,E5EXC,C(=O)[SH1],O=C[SH] +2223,E6,"C(=[O,S])(N)Oc",*=C(N)Oc +2224,"E7 - e.g., aryl carbamates","C1(=O)NS(=O)(=O)[C,c]=,:[C,c]1",O=C1*=*S(=O)(=O)N1 +2225,E8SUB,"P(=O)[O,S]",*P=O +2226,E9EXC,P[OH1],[OH]P +2227,E10,"[$(P(=O)[O,S]);!$(P[OH1])]",* +2228,E11,c(=O)(~c)~c,c~c(~c)=O +2229,E12EXC,"[$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)]",* +2230,E12,"[$(c(=O)(~c)~c);!$([$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)])]",* +2231,E13 - imides,C(=O)-N-C=O,O=CNC=O +2232,N1 - pimary amines,[NX3H2][CX4],C[NH2] +2233,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C +2234,N4EXC,"N=[O,C,N,S]",*=N +2235,N5EXC,"N-[C,c,N]=[C,c,N,n,O,S]",*=*N +2236,N6,"[OH1][C,c,N;!$(C=O)]",*[OH] +2237,N7EXC,[OH1]C=C,C=C[OH] +2238,N8EXC,"[OH1]NC=[O,S]",*=CN[OH] +2239,N9,"[$([NX3H2]!:c),$([NX3H1]([CX4])!:c),$([NX3H0]([CX4])([CX4])!:c)]",* +2240,NUC,"[$([NH2][CX4]),$([NH]([CX4])[CX4]),$([OH1][C,c,N;!$(C=O)]),$([$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]);!$(N=[O,C,N,S]);!$(N-[C,c,N]=[C,c,N,n,O,S]);!$([OH1]C=C);!$([OH1]NC=[O,S])]",* +2241,> 2 ester groups,"C(=O)O[C,H1].C(=O)O[C,H1].C(=O)O[C,H1]",*OC=O.*OC=O.*OC=O +2242,2-halo pyridine,"n1c([F,Cl,Br,I])cccc1",*c1ccccn1 +2243,Acid halide,"C(=O)[Cl,Br,I,F]",*C=O +2244,Acyclic C=C-O,C=[C!r]O,C=CO +2245,Acyl cyanide,N#CC(=O),N#CC=O +2246,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O +2247,Aliphatic long chain,[R0;D2][R0;D2][R0;D2][R0;D2],**** +2248,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1 +2249,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1 +2250,Azido group,N=[N+]=[N-],[N-]=[N+]=N +2251,Azo group,N=N,N=N +2252,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1 +2253,Benzidine,"[cR2]1[cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2][cR2]1[cR2]2[cR2][cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2]2",*c1ccc(c2ccc(*)cc2)cc1 +2254,Betaketo/anhydride,"[C,c](=O)[CX4,CR0X3,O][C,c](=O)",O=***=O +2255,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2256,Carbo cation/anion,"[C+,c+,C-,c-]",* +2257,Catechol,"c1c([OH])c([OH,NH2,NH])ccc1",*c1ccccc1[OH] +2258,Charged oxygen or sulfur atoms,"[O+,o+,S+,s+]",* +2259,Chinone (1),"C1(=[O,N])C=CC(=[O,N])C=C1",*=C1C=CC(=*)C=C1 +2260,Chinone (2),"C1(=[O,N])C(=[O,N])C=CC=C1",*=C1C=CC=CC1=* +2261,Conjugated nitrile group,C=[C!r]C#N,C=CC#N +2262,Crown ether,"[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]",*~C~C~*~C~C~* +2263,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1 +2264,Cyanamide,N[CH2]C#N,N[CH2]C#N +2265,Cyanate/aminonitrile/thiocyanate,"[N,O,S]C#N",*C#N +2266,Cyanohydrins,N#CC[OH],N#CC[OH] +2267,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1 +2268,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1 +2269,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1 +2270,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1 +2271,Diaminobenzene (1),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])c([N+R0,NX3R0,nX3R0])[cR2][cR2]1",*c1ccccc1* +2272,Diaminobenzene (2),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2]c([N+R0,NX3R0,nX3R0])[cR2]1",*c1cccc(*)c1 +2273,Diaminobenzene (3),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2][cR2]c1([N+R0,NX3R0,nX3R0])",*c1ccc(*)cc1 +2274,Diazo group,[N!R]=[N!R],N=N +2275,Diketo group,"[C,c](=O)[C,c](=O)",O=**=O +2276,Disulphide,SS,SS +2277,Enamine,[CX3R0][NX3R0],CN +2278,Ester of HOBT,C(=O)Onnn,nnnOC=O +2279,Four member lactones,C1(=O)OCC1,O=C1CCO1 +2280,Halogenated ring (1),"c1cc([Cl,Br,I,F])cc([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1ccc(*)c(*)c1 +2281,Halogenated ring (2),"c1ccc([Cl,Br,I,F])c([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1cccc(*)c1* +2282,Heavy metal,"[Hg,Fe,As,Sb,Zn,Se,se,Te,B,Si]",* +2283,Het-c-het not in ring,"[NX3R0,NX4R0,OR0,SX2R0][CX4][NX3R0,NX4R0,OR0,SX2R0]",*C* +2284,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1 +2285,Hydroxamic acid,C(=O)N[OH],O=CN[OH] +2286,Imine,C=[N!R],C=N +2287,Isolated alkene,"[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]=[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]",*=* +2288,Ketene,C=C=O,C=C=O +2289,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1 +2290,Michael acceptor (1),"C=!@CC=[O,S]",*=CC=C +2291,Michael acceptor (2),"[$([CH]),$(CC)]#CC(=O)[C,c]",*C(=O)C#* +2292,Michael acceptor (3),"[$([CH]),$(CC)]#CS(=O)(=O)[C,c]",*S(=O)(=O)C#* +2293,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O +2294,Michael acceptor (5),"[$([CH]),$(CC)]#CC(=O)O[C,c]",*OC(=O)C#* +2295,N oxide,"[NX4,nX3][OX1]",*O +2296,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1 +2297,N-c-halo,"NC[F,Cl,Br,I]",*CN +2298,N-halo,"[NX3,NX4][F,Cl,Br,I]",** +2299,N-hydroxylpyridine,n[OH],n[OH] +2300,Nitro group,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]",* +2301,N-nitroso,[#7]-N=O,NN=O +2302,Oxime (1),"[C,c]=N[OH]",*=N[OH] +2303,Oxime (2),"[C,c]=NOC=O",*=NOC=O +2304,Oxygen-nitrogen single bond,"[OR0,NR0][OR0,NR0]",** +2305,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F +2306,Peroxide,OO,OO +2307,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1 +2308,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1 +2309,Phosphor,P,P +2310,Phthalimide,"[cR,CR]~C(=O)NC(=O)~[cR,CR]",*~C(=O)NC(~*)=O +2311,Polycyclic aromatic hydrocarbon (1),"a1aa2a3a(a1)[a,A]=,:[a,A]-,:[a,A]=,:[a,A]3A=AA2",*1*=**2:*3:*1:*:*:*:*:3:*=**=2 +2312,Polycyclic aromatichydrocarbon (2),a21aa3a(aa1aaaa2)aaaa3,*1:*:*:*2:*:*3:*:*:*:*:*:3:*:*:2:*:1 +2313,Polycyclic aromatichydrocarbon (3),a31a(a2a(aa1)aaaa2)aaaa3,*1:*:*:*2:*(:*:1):*:*:*1:*:*:*:*:*:1:2 +2314,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C +2315,Quaternary nitrogen (1),"[s,S,c,C,n,N,o,O]~[nX3+,NX4+](~[s,S,c,C,n,N])~[s,S,c,C,n,N]",*~*(~*)~* +2316,Quaternary nitrogen (2),"[s,S,c,C,n,N,o,O]~[n+,N+](~[s,S,c,C,n,N,o,O])(~[s,S,c,C,n,N,o,O])~[s,S,c,C,n,N,o,O]",*~*(~*)(~*)~* +2317,Quaternary nitrogen (3),[*]=[N+]=[*],*=[N+]=* +2318,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2319,Silicon halogen,"[Si][F,Cl,Br,I]",*[Si] +2320,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1 +2321,Sulfinic acid,"[SX3](=O)[O-,OH]",*S=O +2322,Sulfonic acid,"[C,c]S(=O)(=O)O[C,c]",*OS(*)(=O)=O +2323,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2324,Sulfur oxygen single bond,[SX2]O,OS +2325,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-] +2326,Sulphur nitrogen single bond,[SX2H0][N],NS +2327,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1 +2328,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1 +2329,Thiocarbonyl group,"[C,c]=S",*=S +2330,Thiol (1),[S-],[SH-] +2331,Thiol (2),[SH],[SH] +2332,Three-membered heterocycle,"*1[O,S,N]*1",*1**1 +2333,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2334,Triphenyl methylsilyl,"[SiR0,CR0](c1ccccc1)(c2ccccc2)(c3ccccc3)",c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2335,Triple bond,C#C,C#C +2336,Aromatic NO2,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-c(:*):*",*c(:*):* +2337,Deuterium,[2H],[2HH] +2338,C13,[13#6],[13CH4] +2339,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1 +2340,"Si,B,Se atoms","[Si,B,Se]",* +2341,Hetero imides,[!#6]-[CH2]-N1C(=O)CCC(=O)1,*CN1C(=O)CCC1=O +2342,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O +2343,Acyclic imines,"C-!@[NX2]=[C!R,#1]-C",C*=NC +2344,Alkyl esters of S or P,"[S,P](=O)OC",CO*=O +2345,Ugly P compounds,"P(=[O,S])[C,N]([C,N])[C,N]",**(*)P=* +2346,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN +2347,Acyclic N-C-N,N-!@[CX4]-!@N,NCN +2348,Acyclic N-S,N-!@[SX2]-*,*SN +2349,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O +2350,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O +2351,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1 +2352,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O +2353,Acyl halide,"O=C-[F,Cl,Br,I]",*C=O +2354,Alpha halo carbonyl,"O=C-C-[F,Cl,Br,I]",*CC=O +2355,Sufonyl halide,"S(=O)(=O)-[F,Cl,Br,I]",*[SH](=O)=O +2356,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N +2357,26,N-C(=S)-N,NC(N)=S +2358,Terminal vinyl,[CH2D1]=[CD2]-!@*,*C=C +2359,28,S=P~*,*~P=S +2360,Thio cyanates,S-C#N,N#CS +2361,Thionyl,[Sv4](=O)(-!@[!#1])-!@[!#1],*S(*)=O +2362,N-Haloamines,"N-[F,Cl,Br,I]",*N +2363,N-C-Hal or cyano methyl,"N-C-[F,Cl,Br,I,$(C#N)]",*CN +2364,Alpha beta-unsaturated ketones; center of Michael reactivity,"[$(C#N),$(N(~O)~O),$(C=O),$(S(=O)=O),$(C(F)(F)F),Cl][C!H0]=[C!H0]",*C=C +2365,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O +2366,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2] +2367,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2] +2368,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N +2369,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO +2370,42,S-S,SS +2371,43,O~O,O~O +2372,Aziridine-like N in 3-membered ring,N~1~*~*1,*1~*~N~1 +2373,Aryl iodide,I-c:*,*:cI +2374,Aryl bromide,Br-c:*,*:cBr +2375,Multiple aromatic rings,a1aaa2a(a1)aaa(a2):a,*:*1:*:*:*2:*:*:*:*:*:2:*:1 +2376,S/PO3 groups,"[P,S](~O)(~O)~O",O~*(~O)~O +2377,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3 +2378,Too many cyano groups (>1),C#N.C#N,C#N.C#N +2379,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH] +2380,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O +2381,Chlorates,Cl~O,O~Cl +2382,High halogen content (>3),"[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I]",*.*.*.* +2383,Filter1_2_halo_ether,"[Cl,Br,I][CX4][CX4][$([O,S,N]*),Cl,Br,I]",*CC* +2384,Filter2_acyl_phosphyl_sulfonyl_halide,"[C,S,P](=O)[F,Cl,Br,I]",**=O +2385,Filter3_allyl_halide,"[F,Cl,Br,I][CX4]C=C",*CC=C +2386,Filter4_alpha_halo_carbonyl,"[Br,Cl,I][C!H0]C=[O,S]",*CC=* +2387,Filter5_azo,"[!#7,#1]~[NX2R0]=[NX2R0]~[!#7,#1]",*~N=N~* +2388,Filter6_benzyl_halide,"[Br,Cl,I][CX4]c",*Cc +2389,Filter7_diazo,[!#7]~[NX2]~[NX1],*~N~N +2390,Filter8_thio_isocyanat_diimin,"N=C=[N,O,P,S]",*=C=N +2391,Filter9_metal,"[!#1!#6!#7!#8!#9!#15!#16!#17]~[*,#1]",*~* +2392,Filter10_Terminal_vinyl,"[CH2]=[CH][N,O,P,S;R0]",*[CH]=C +2393,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O +2394,Filter12_nitroso,"[*,#1]~[NX2]~[OX1]",*~N~O +2395,Filter13_PS_double_bond,"S=P~[*,#1]",*~P=S +2396,Filter14_thio_oxopyrylium_salt,"c1ccc[s,o;X2]c1",*1ccccc1 +2397,Filter15_thiosulfate,[SX4](~S)(~O)(~O)~*,*~S(~O)(~O)~S +2398,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C +2399,Filter17_trialkyl_phosphin2,[PX4](~[!O!S])([#6])([#6])[#6],*~P(C)(C)C +2400,Filter18_oxime_ester,"[!#7,#1]C=NO[C,S,P](=O)*",*C=NO*(*)=O +2401,Filter19_hydroxyimide_ester,O=C[NX3](C=O)OC(=O)*,*C(=O)ON(C=O)C=O +2402,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN +2403,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH] +2404,Filter22_sulfonium_salt,*[SX3](*)*,*S(*)* +2405,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O +2406,Filter24_react_imide,"*C([F,Cl,Br,I,$(OS(=O)(=O)*)])=[NX2]*",*N=C(*)* +2407,Filter25_sulfonyl_halide,"*S(=O)(=O)[F,Cl,Br,I]",*S(*)(=O)=O +2408,Filter26_alkyl_halide,"AA[CH2][F,Cl,Br,I,$(OS(=O)(=O)*)]",**[CH2]* +2409,Filter27_anhydride,"*[C,S](=O)O[C,S](=O)*",**(=O)O*(*)=O +2410,Filter28_halo_pyrimidine,"c1nc(ncc1)[Br,I]",*c1ncccn1 +2411,Filter29_thioester,"CC(=[OX1,SX1,NH])[SX2][*,#1]",*SC(=*)C +2412,Filter30_beta_halo_carbonyl,"[#6,#1]C(=O)CC[Br,I]",*CCC(*)=O +2413,Filter31_SO_bond,"[*,#1][SX2R0]O[*,#1]",*OS* +2414,Filter32_OO_bond,"[*,#1][OR0]O[*,#1]",*OO* +2415,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3] +2416,Filter34_isotope,"[2#1,3#1,13C,14C,15N,125I,23F,22Na,32P,33P,35S,45Ca,57Co,103Ru,141Ce]",* +2417,Filter35_PP_bond,P-P,PP +2418,Filter36_SS_double_bond,S=S,S=S +2419,Filter37_silicate,[Si]~O,O~[SiH4] +2420,Filter38_aldehyde,O=[CH]*,*[CH]=O +2421,Filter39_imine,C[CR0]=[NR0][*!O],*N=CC +2422,Filter40_epoxide_aziridine,"C1C[N,S,O]1",*1CC1 +2423,Filter41_12_dicarbonyl,*C(=O)C(=O)*,*C(=O)C(*)=O +2424,Filter42_12_dicarbonyl_tautomer,[*!$(C[OH])]=C([OH])C(=O)*,*C(=O)C(=*)[OH] +2425,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O +2426,Filter44_michael_acceptor2,"[#6,#1,OH0][C!$(C1(=O)C=CC(=O)C=C1)](=O)C=[C!$(C[Nv3X3,OH])]",*C(=O)C=C +2427,Filter45_allyl_halide2,"[Br,Cl,I][CX4]C=[C,N,P]",*CC=* +2428,Filter46_nhalide,"N[F,Cl,Br,I]",*N +2429,Filter47_SO2F,O=S(=O)(*)F,*S(=O)(=O)F +2430,Filter48_FOSO,O=S(*)OF,*S(=O)OF +2431,Filter49_halogen,"[*,#1]~[F,Cl,Br,I]~[*,#1]",*~*~* +2432,Filter50_grignard,"C[Mg][F,Cl,Br,I]",*[Mg]C +2433,Filter51_PN3,N[PX3](N)N,NP(N)N +2434,Filter52_NC_haloamine,"NC[F,Cl,Br,I]",*CN +2435,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +2436,Filter56_SS_bond,S-S,SS +2437,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1 +2438,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1 +2439,Filter59_phoshorous_ylide,C=P,C=P +2440,Filter60_Acyclic_N-S,N!@[SX2],N~S +2441,Filter61_phosphor_halide_and_P_S_bond,"[#15]~[F,Cl,Br,I,#16]",*~P +2442,Filter62_oxo_thio_halide,"[O,S]~[Cl,Br,I]",*~* +2443,Filter63_polyaromatic,a1aaaa2ccc3ccccc3c12,*1:*:*c2*(:*:1)ccc1ccccc12 +2444,Filter64_halo_ketone_sulfone,"[#6][C,S](=[O,S])C[F,Cl,Br,I]",*C*(=*)C +2445,Filter65_alkyl_sulfonate,"[#6][P,S](~[OX1])(~[OX1])O[C!H0]",CO*(C)(~O)~O +2446,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F +2447,Filter67_S_or_O_C_triplebond_N,"[O,S]C#N",*C#N +2448,Filter68_anthracene_acridine,a1aaac2cc3ccccc3cc12,*1:*:*c2cc3ccccc3cc2*:1 +2449,Filter69_thio_carbonate,"[O,S]C(=[O,S])[O,S]",*C(*)=* +2450,Filter70_AlkylCN2,*(C#N)C#N,N#C*C#N +2451,Filter71_thio_anhydride,"*C(=[O,S])[O,S]C(=[O,S])*",*C(=*)*C(*)=* +2452,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH] +2453,Filter73_thio_ketone,CC(=S)C,CC(C)=S +2454,Filter74_thiol,*[SX2H],*[SH] +2455,Filter75_alkyl_Br_I,"[C!H0][Br,I]",*C +2456,Filter76_S_ester,CC(=S)O,CC(O)=S +2457,Filter77_alkyl_NO2,"[*!#7]~[#6]-,=CN(~O)(~O)",*~CCN(~O)~O +2458,Filter78_bicyclic_Imide,*~@C1C(=O)NC(=O)C(~@*)1,*~C1C(~*)C(=O)NC1=O +2459,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1 +2460,Filter80_Thioepoxide_aziridone,"[N,S]1[C,N,S][C,N,S]1",*1**1 +2461,Filter81_Thiocarbamate,"S!@C(=!@[O,S])!@[#7]",*=C(~N)~S +2462,Filter82_pyridinium,"[c,n]1[c,n][c,n][c,n][c,n]n(C)1",Cn1*:*:*:*:*1 +2463,Filter83_per_halo_chain,"[F,Cl,Br,I]C-,=;!@C([F,Cl,Br,I])-,=;!@C([F,Cl,Br,I])",*CC(*)C* +2464,Filter84_nitrogen_mustard,"[N,P,Se,S][C!H0]C[Br,Cl,I]",*CC* +2465,Filter85_keto_acrylonitrile,*C(=O)C(=!@[C!H0])C#N,*C(=O)C(=C)C#N +2466,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N +2467,Filter87_crowns,"[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[O,N]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@C",*C~C*C~C*C~C*C +2468,Filter88_ene_sulfone,[C!H0]=CS(=O)(=O)*,*S(=O)(=O)C=C +2469,Filter89_hydroxylamine,"[*!$(C=O)]!@N!@O[*,#1]",*~N~O* +2470,Filter90_N_double_bond_S,N=!@S,N=S +2471,Filter92_trityl,*(c1ccccc1)(c1ccccc1)(c1ccccc1),c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2472,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O +2473,Filter94_2_halo_pyridine,"c1nc(ccc1)[Br,I,Cl,F]",*c1ccccn1 +2474,Anhydride,C(=O)OC(=O),O=COC=O +2475,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1 +2476,Any carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2477,HOBT ester,C(=O)Onnn,nnnOC=O +2478,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-] +2479,Imine2,"[#6,#8,#16]-[CH1]=[NH1]",*C=N +2480,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N +2481,Cyanohydrin,N#CC[OH],N#CC[OH] +2482,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl +2483,P/S halide,"[P,S][F,Cl,Br,I]",** +2484,Quaternary,"[C+,Cl+,I+,P+,S+]",* +2485,Unacceptable atoms,[!#6;!#7;!#8;!#16;!#1;!#3;!#9;!#11;!#12;!#15;!#17;!#19;!#20;!#30;!#35],* +2486,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2487,b-Carbonyl quaternary nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2488,Benzylic quaternary nitrogen,cC[N+],cC[N+] +2489,Phosphorane,C=P,C=P +2490,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S +2491,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2492,Sulfonate,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2493,Heteroaryl sulfonate,"a-S(=O)(=O)-O[$([a&!#6]),$(c[a&!#6]),$(cc[a&!#6]),$(ccc[a&!#6]),$(cccc[a&!#6]),$(ccccc[a&!#6])]",*OS(*)(=O)=O +2494,Sulfate ester,"COS(=O)O[C,c]",*OS(=O)OC +2495,Polyacidic,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2496,Thiol,[SH],[SH] +2497,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1 +2498,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +2499,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2500,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2501,Allene,*=C=*,*=C=* +2502,Azide,"[$(*-[NX2-]-[NX2+]#[NX1]),$(*-[NX2]=[NX2+]=[NX1-]),$(N=N=N)]",* +2503,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O +2504,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2505,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH] +2506,Ester,[#6]-C(=O)O-[#6],COC(C)=O +2507,Imine 1,"[#6,#8,#16]-C(=[NH1])[#6,#8,#16]",*C(*)=N +2508,Imine 3,C=[NH],C=N +2509,Thioketone,CC(=S)C,CC(C)=S +2510,Thionoester,COC(=S)C,COC(C)=S +2511,Thioamide,CC(=S)N,CC(N)=S +2512,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC +2513,Long aliphatic chain,"[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]",******* +2514,Unbranched chain,"[$([A&D2]),$([A&D1])]!@[A&D2]!@[A&D2]!@[A&D2]!@[A&D2]!@[$([A&D2]),$([A&D1])]",*~*~*~*~*~* +2515,Dye 25,acC=&!@Cca,*cC=Cc* +2516,Isonitrile,[N+]#[C-],[C-]#[NH+] +2517,Thiocyanate,SC#N,N#CS +2518,Dye 16 (1),"c[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c +2519,Nitro aromatic 2+,"a-[$([NX3](=O)=O),$([NX3+](=O)[O-])].a-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",**.** +2520,Dye 29,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-caac-[$(N(C)C),$([NH]C),$([NH2])]",*c*:*c* +2521,Dye 1 (1),"c1cccc(C(=O)[C,c]([#7])=,:[C,c]([#7])C2(=O))c12",N*1=*(N)C(=O)c2ccccc2C1=O +2522,Dye 7,"N=C1[#6]:,=[#6]C(=[C,N])[#6]:,=[#6]1",*=C1C:CC(=N)C:C1 +2523,Dye 11,"*=,:[#6]C([#6]=,:*)[#6]=,:*",*=CC(C=*)C=* +2524,Dye 9,ac-*=&!@*-&!@C(=O)-&!@ca,*c*=*C(=O)c* +2525,Dye 32,"c1cccc2C(=O)C(C:,=*)C(=O)c12",*:CC1C(=O)c2ccccc2C1=O +2526,Dye 6,c12cccc(C(=O)C(ca)C(=O)3)c2c3ccc1,*cC1C(=O)c2cccc3cccc(c23)C1=O +2527,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1 +2528,Dye 2,OCccCO,OCccCO +2529,Dye 26,c1ccccc1-n2nnnc2[CH2]*,*[CH2]c1nnnn1-c1ccccc1 +2530,Perhalo_ketone,"O=CC(-[F,Cl,Br,I])([F,Cl,Br,I])-[F,Cl,Br,I]",*C(*)(*)C=O +2531,Beta halo carbonyl,"O=CCC[F,Cl,Br,I]",*CCC=O +2532,4-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[n]:[c,n]:[c,n]1",*c1*:*n*:*1 +2533,2-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[c,n]:[c,n]:[n]1",*c1*:*:*:*n1 +2534,Hetero_hetero,"*[N,S,O]-&!@[N,S,O][#6]",***C +2535,Disulfide,SS,SS +2536,Vinyl michael acceptor1,"[#6]-[CH1]=C-C(=O)[#6,#7,#8]",*C(=O)C=CC +2537,Vinyl michael acceptor2,"[CH2]=C-C(=O)[#6,#7,#8]",*C(=O)C=C +2538,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N +2539,Michael acceptor 6,"[#6,#7]-&!@[#6](=&!@[CH])-&!@C(=O)-&!@[C,N,O,S]",*C(=[CH])C(*)=O +2540,Alkynyl michael acceptor1,"[#6]-C#CC(=O)[#6,#7,#8]",*C(=O)C#CC +2541,Alkynyl michael acceptor2,"[CH1]#CC(=O)-[#6,#7,#8]",*C(=O)C#C +2542,Nitroalkane,"C[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*C +2543,Nitrate,"[#6]-O-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*OC +2544,Oxalyl,O=C-&!@C=O,O=CC=O +2545,Dipeptide,*-C(=O)-&!@[NH]-C-&!@C(=O)-&!@[NH]-*,*NC(=O)CNC(*)=O +2546,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-] +2547,Triphenylphosphine,a-P(-a)-a,*P(*)* +2548,Phosphoric acid,[OH]-P(=O)(-O)-*,*P(=O)(O)O +2549,Phosphoric ester,COP(=O)(-*)O,*P(O)(=O)OC +2550,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2551,Tri phosphoric esters,[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6],*P(=O)(OC)OC.*P(=O)(OC)OC.*P(=O)(OC)OC +2552,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O +2553,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12 +2554,Poly(azo(anthracene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1[c,n]c3:[c,n]:[c,n]:[c,n]:[c,n]:c3[c,n]2",*1:*:*c2*c3*:*:*:*c3*c2*:1 +2555,Poly(azo(phenanthrene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1:[c,n]:[c,n]:c3:[c,n]:[c,n]:[c,n]:[c,n]:c23",*1:*:*c2c(*:1)*:*c1*:*:*:*c12 +2556,Dye 31,a1aaac2ac3acac4aaac(c34)c12,*1:*:*c2c(*:1)*c1*c*c3*:*:*c2c31 +2557,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21 +2558,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O +2559,"Epoxide, aziridine, thioepoxide","C1[O,S,N]C1",*1CC1 +2560,Propiolactone,C1(=O)OCC1,O=C1CCO1 +2561,b-Lactam,N1CCC1=O,O=C1CCN1 +2562,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2563,Aromatic sulfonic ester,"[#6,#7]-S(=O)(=O)Oc",*S(=O)(=O)Oc +2564,Quinone,"[$([o,n]=c1ccc(=[o,n])cc1),$([O,N]=C1C=CC(=[O,N])C=C1),$([O,N]=C1[#6]:,=[#6]C(=[O,N])[#6]:,=[#6]1)]",* +2565,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2566,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2567,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2568,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1 +2569,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2570,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1 +2571,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2572,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2573,Acid_anhydrides,C(=O)OC(=O),O=COC=O +2574,Acid_halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2575,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1 +2576,Active_phosphate,"P(=S)([OH1,O$(O[#6])])([OH1,O$(O[#6])])[S,O]",*P(*)(*)=S +2577,Acyl_cyanide,C(=O)-C#N,N#CC=O +2578,Adjacent_ring_double_bonds,[*;R]=[*;R]=[*;R],*=*=* +2579,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F +2580,Alkyl_halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2581,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C +2582,Alpha_halo_carbonyl,"[C;!$(C[N])](=O)!@[C;h1,h2;H1,H2][F,Cl,Br,I]",*C~C=O +2583,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O +2584,Aminonitrile,NC#N,NC#N +2585,Any_carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2586,Aromatic_azides,"c[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*c +2587,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-] +2588,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2589,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1 +2590,B-carbonyl_quaternary_nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2591,Benzylic_quaternary_nitrogen,"cC[N+,NX4]",*Cc +2592,Beta-carbonyl_quaternary_nitrogen,"C(=O)C[N+,n+,NX4,nX4]",*CC=O +2593,Beta-fluoro-ethyl-on,"[C;H2$(CF),H1$(C(F)F)]!@[CH2][N,O]",*[CH2]~C +2594,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2595,Carbazides,"C(=O)[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*C=O +2596,CCl3-CHO_releasing,"C(Cl)(Cl)(Cl)C([O,S])[NX3]",*C(N)C(Cl)(Cl)Cl +2597,Conjugated_dithioether,SC(=[!r])S,*=C(S)S +2598,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1 +2599,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1 +2600,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1 +2601,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2602,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2603,Diacetylene,C#CC#C,C#CC#C +2604,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-] +2605,Diazonium_salt,[N+]#N,N#[NH+] +2606,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O +2607,Dinitrobenzene_1,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc1",*c1ccccc1* +2608,Dinitrobenzene_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])c1",*c1ccc(*)cc1 +2609,Dinitrobenzene_3,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1cccc(*)c1 +2610,Dithiocarbamate,NC(=S)S,NC(S)=S +2611,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1 +2612,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1 +2613,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS +2614,Enyne,C=!@CC#C,C#CC=C +2615,"Epoxides,_thioepoxides,_aziridines","C1[O,S,N]C1",*1CC1 +2616,Ester_of_HOBT,C(=O)Onnn,nnnOC=O +2617,Flavin,"c1cccc(NC(=NC(=[N,S,O])NC(=O)3)C3=N2)c12",*=C1NC(=O)C2=Nc3ccccc3NC2=N1 +2618,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2 +2619,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF +2620,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F +2621,Four_member_lactones,C1(=O)OCC1,O=C1CCO1 +2622,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN +2623,Geminal_dinitriles,N#CCC#N,N#CCC#N +2624,"Halo-pyridine, -diazoles and -triazoles","[Cl,Br,I]c1[c,n][c,n][c,n][c,n]n1",*c1*:*:*:*n1 +2625,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1 +2626,Imines_(not_ring),"[#6][CR0](=[NR0,OR0])[#6]",*=C(C)C +2627,Isocyanates_and_isothiocyanates,"N=C=[S,O]",*=C=N +2628,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S +2629,Michael_phenyl_ketone,c1ccccc1C(=O)C=!@CC(=O)!@*,*~C(=O)C=CC(=O)c1ccccc1 +2630,Nitrobenz-azadiazole_1,"c1ccc(n[o,s]n2)c2c1[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c1cccc2n*nc12 +2631,Nitrobenz-azadiazole_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc(n[o,s]n2)c2c1",*c1ccc2n*nc2c1 +2632,Nitrosamine,N-[N;X2](=O),NN=O +2633,Noname,"N1=C[S,NH1]C(=[C,N,P][C,N,O,P])C1(=O)",**=C1*C=NC1=O +2634,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-] +2635,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN +2636,Orthoester,C(O)(O)[OH],OC(O)[OH] +2637,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH] +2638,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1 +2639,P_or_S_halides,"[P,S][Cl,Br,F,I]",** +2640,P-aminoaryl_diazo,Nc1aaa(N!@=N)aa1,Nc1*:*:*(N~N):*:*1 +2641,PCP,PCP,PCP +2642,Paranitrophenyl_esters,"C(=O)Oc1ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1ccc(OC=O)cc1 +2643,Pentahalophenyl,"c1c([F,Cl])c([F,Cl])c([F,Cl])c([F,Cl])c1([F,Cl])",*c1cc(*)c(*)c(*)c1* +2644,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2645,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34 +2646,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1 +2647,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O +2648,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2649,Phosphorus_halide,"[S,P][F,Cl,Br,I]",** +2650,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2651,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc +2652,Polyines,CC#CC#CC,CC#CC#CC +2653,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1 +2654,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12 +2655,Polysulfide,*[SX2][SX2][SX2]*,*SSS* +2656,Sulphur_halide,"[#16][F,Cl,Br,I]",*S +2657,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34 +2658,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1 +2659,Reactive_carbonyls,"[C;!r](=[O,S])[S;!r]",*=CS +2660,Ring_triple_bond,"[C,c;R]#[C,c;R]",*#* +2661,S=N (not_ring),[S;R0]=[N;R0],N=S +2662,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O +2663,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2664,Sulphate_ester,"COS(=O)O[C,c]",*OS(=O)OC +2665,Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2666,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S +2667,Tetraazinane,C1NNC=NN1,C1NNC=NN1 +2668,Thioles_(not_aromatic),[!a][SX2;H1],*S +2669,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S +2670,Three_membered_heterocycle,"*1[O,S]*1",*1**1 +2671,Tri_pentavalent_S,"[#16v3,#16v5]",* +2672,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1 +2673,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1 +2674,Triphenylphosphines,P(c1aaaaa1)(c1aaaaa1)(c1aaaaa1),*1:*:*c(P(c2*:*:*:*:*2)c2*:*:*:*:*2)*:*:1 +2675,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1 +2676,Vinyl_halide,"[Cl,Br,I]C=[!O!R]",*C=* +2677,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O +2678,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O +2679,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1 +2680,Oxime,"[#6]C(=!@N[$(OC),$([OH])])[#6]",*N=C(C)C +2681,Hydrazone,[#6]C(=!@NNa)[#6],*NN=C(C)C +2682,Nitrosone_not_nitro,[$(N(~!@[#6])!@O);!$([N+]([O-])=O)],* +2683,Thiocarbonyl_group,C=S,C=S +2684,Enamine_like,C=[NH],C=N +2685,Analine,"c1ccccc1[NH2,NH3+]",*c1ccccc1 +2686,Acid_anhydrides_2,"[#6]C(=O)!@OC(=!@[N,O])[#6]",*=C(C)O~C(C)=O +2687,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F +2688,Triple_bond,[#6]C#[CH],CC#C +2689,Thiatetrazolidine,"[$(Sc1nnn[nH,n-]1),$(Sc1nn[nH,n-]n1)]",* +2690,Glycol,"[#6][O;R0][$(C([#6])[#6]),$([CH][#6]),$([CH2])][O;R0][#6]",CO*OC +2691,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O +2692,Formate_formide,"O=[CH][O,N][#6]",C*[CH]=O +2693,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1 +2694,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1 +2695,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1 +2696,Thiazolidinone,O=C1CSCN1,O=C1CSCN1 +2697,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1 +2698,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1 +2699,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1 +2700,Ethene,C=[CH2],C=C +2701,Cyclobutene,C1CC=C1,C1CC=C1 +2702,Poly_sub_atomatic,*!@c1c(!@*)c(!@*)c(!@*)c(!@*)c1,*~c1cc(~*)c(~*)c(~*)c1~* +2703,Isotopes,"[2#1,3#1,11C,11c,14C,14c,125I,32P,33P,35S]",* +2704,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C +2705,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-] +2706,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-] +2707,Sulphur atom (1),[SX2H1],[SH] +2708,Sulphur atom (2),"[$([SX2H0]);!$([S][#6X3,#7X2]);!$([S][CX4H0])]",* +2709,Sulphur atom (3),"[$([SX2H0][#6X3,#7X2]);!$([S](~[#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2710,Sulphur atom (4),[$([S][*D4H0]);$([SX2H0])],* +2711,Sulphur atom (5),"[$([SX2H0]([#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2712,Sulphur atom (6),[sX2r5],s +2713,Sulphur atom (7),[$([#16X3](=[OX1]));$([#16]);!$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2714,Sulphur atom (8),[$([#16X3](=[OX1]));$([#16]);$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2715,Aldehyde carbon atoms,[$([CX3H1](=O)[#6])],* +2716,Phosphor with double bonded sulphur,[$([PX4]);$([P]=[S])],* +2717,sp3 hybridized carbon atoms (1),[$([CX4]([#6X3])([#6X3])[#6X3]);!$([CH0])],* +2718,sp3 hybridized carbon atoms (2),"[$([CX4][N]);!$([CH0]);!$([C][N]([#6X3,#7X2])[#6X3,#7X2]);!$([C][N]=[#6X3]);!$([CX4][NX3][C]=[O])]",* +2719,sp3 hybridized carbon atoms (3),"[!$([CH0]);$([CX4]([#6X3])[#6X3]),$([CX4][#7]=[#6X3]),$([CX4]([#8])[#8]);!$([CX4]([#8])[#8][C]=[O])]",* +2720,sp3 hybridized carbon atoms (4),[$([CX4][S]);!$([CH0]);!$([C][S]=[O])],* +2721,sp3 hybridized carbon atoms (5),"[$([CX4][#6X3]~[#8]),$([CX4][#6X3](~[#7])~[#7]),$([CX4][#6X2]),$([CX4][CX3]=[CX3]-[#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3]);!$([CX4][#6X3](=[#8])-[#8]);!$([CX4][CX3]([CX3])=[CX3]-[#6X3])]",* +2722,sp3 hybridized carbon atoms (6),[$([CX4][O]);!$([CH0]);!$([C][O][C]=[O]);!$([CX4]1[O][C]1)],* +2723,sp3 hybridized carbon atoms (7),[$([CX4][#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3])],* +2724,sp3 hybridized carbon atoms (8),"[$([CX4][#7](~[#6X3,#7X2])~[#6X3,#7X2]);!$([CH0])]",* +2725,sp3 hybridized carbon atoms (9),[$([CX4][S](=[O])=[O]);!$([CH0])],* +2726,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C +2727,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C +2728,sp3 hybridized carbon atoms (12),[$([CX4][NX3H1][C]=[O]);!$([CH0])],* +2729,sp2 hybridized carbon atoms (1),"[$([CX3H2]);$([C]=[#6X3,#7X2]-[#6X3,#7X2])]",* +2730,sp2 hybridized carbon atoms (2),"[$([CX3H1]);$([C]=[#6X3,#7X2]-[#6X3,#7X2]);!$([C](-[#6X3,#7X2])=[#6X3,#7X2]-[#6X3,#7X2])]",* +2731,sp2 hybridized carbon atoms (3),[$([cH1]);$([c](:[#7]):[#7])],* +2732,sp2 hybridized carbon atoms (4),"[$([ch1]);!$([ch1]1:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]:[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]1);$([ch1]1:[c](-[NX3]):[c]:[c]:[c]:[c]1),$([c]1:[c]:[c]:[c](-[NX3]):[c]:[c]1)]",* +2733,sp2 hybridized carbon atoms (5),"[$([CX3]);$([CX3]=[CX3]);!$([CH0]);!$([CX3](-[#6X3,#7X2])=[CX3]);!$([CX3]=[CX3]-[#6X3,#7X2])]",* +2734,sp2 hybridized carbon atoms (6),[$([cH1]);$([c]:[#16])],* +2735,sp2 hybridized carbon atoms (7),"[$([ch1]);$([c]1:[c]:[c]:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]1),$([c]1:[c]:[c]:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1)]",* +2736,sp2 hybridized carbon atoms (8),"[$([ch1]);!$([c]1:[c]:[c]:[c](-[O]-[C]=[O]):[c]:[c]1);$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1),$([c]1:[c]:[c]:[c](-[O,SX2]):[c]:[c]1)]",* +2737,sp2 hybridized carbon atoms (9),[$([cH1]);$([c]1:[c]:[#16]:[c]:[c]1)],* +2738,sp2 hybridized carbon atoms (10),"[$([ch1]);$([ch1]1:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]1:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]:[c]-[O,SX2]);!$([ch1]:[c]-[O]-[C]=[O])]",* +2739,sp2 hybridized carbon atoms (11),"[$([CX3H1,cX3H1]);!$([ch1]1:[c]:[c]:[#7]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]1);!$([ch1]:[#7])]",* +2740,sp2 hybridized carbon atoms (12),"[$([ch1]1:[c]:[c]:[#7]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]1),$([ch1]:[#7])]",* +2741,Nitrogen atoms (1),"[$([NX3H0]);!$([NX3][#6X3,#7X2])]",* +2742,Nitrogen atoms (2),"[$([NX3]);$([H1,H2])]",* +2743,Nitrogen atoms (3),[$([N]([#6X3]1)[#6X3]=[#6X3][#6X4][#6X3]=1)],* +2744,Nitrogen atoms (4),"[$([NX3H0]);$([NX3][#6X3,#7X2]);!$([NX3]([#6X3,#7X2])[#6X3,#7X2])]",* +2745,Nitrogen atoms (5),"[$([nr6]),$([NX2]=[C])]",* +2746,Nitrogen atoms (6),"[$([N]);$([NX3H0]([#6X3,#7X2])[#6X3,#7X2]),$([NX2H1][C]=[O])]",* +2747,Nitrogen atoms (7),[nr5H0],n +2748,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21 +2749,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C +2750,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1 +2751,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1 +2752,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1 +2753,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1 +2754,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1 +2755,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1 +2756,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1 +2757,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1 +2758,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1 +2759,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1 +2760,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1 +2761,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2 +2762,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC +2763,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1 +2764,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1 +2765,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1 +2766,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1 +2767,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1 +2768,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1 +2769,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1 +2770,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1 +2771,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1 +2772,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12 +2773,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1 +2774,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1 +2775,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1 +2776,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1 +2777,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1 +2778,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1 +2779,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2 +2780,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2 +2781,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1 +2782,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2 +2783,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +2784,4-chlorobenzene,Clc1ccc([*:1])cc1,Clc1ccc([*:1])cc1 +2785,4-nitrobenzene,[O-][N+](=O)c1cc([*:1])c([*:1])cc1,O=[N+]([O-])c1ccc([*:1])c([*:1])c1 diff --git a/Experiments/E. 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Coli Iteration Outputs/fsr/iter 1/iter1_fsr_85.smi b/Experiments/E. Coli Iteration Outputs/fsr/iter 1/iter1_fsr_85.smi new file mode 100644 index 0000000000000000000000000000000000000000..df69bcb092c6f0aaccc25e5aa7d8cb41303f2144 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 1/iter1_fsr_85.smi @@ -0,0 +1,5 @@ +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +COC1CN(c2ccc3c(=O)c(C(=O)O)cn(CC(C)C)c3c2)CCN1C +CON=C(O)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nncn3C)CSC12)c1csc(O)n1 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 1/iter1_fsr_85.txt b/Experiments/E. Coli Iteration Outputs/fsr/iter 1/iter1_fsr_85.txt new file mode 100644 index 0000000000000000000000000000000000000000..df69bcb092c6f0aaccc25e5aa7d8cb41303f2144 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 1/iter1_fsr_85.txt @@ -0,0 +1,5 @@ +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +COC1CN(c2ccc3c(=O)c(C(=O)O)cn(CC(C)C)c3c2)CCN1C +CON=C(O)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nncn3C)CSC12)c1csc(O)n1 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 1/iter1_gen_fsr.txt b/Experiments/E. Coli Iteration Outputs/fsr/iter 1/iter1_gen_fsr.txt new file mode 100644 index 0000000000000000000000000000000000000000..c8c945e10fe1f68bdcddcd572257de697be6e30f --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 1/iter1_gen_fsr.txt @@ -0,0 +1,100 @@ +CC[N+](C)(C)CN=C(N)n1cccn1 +Oc1ccc(O)c(Oc2cccc3ccccc23)c1O +CC1CC(O)C(N)C(N)=C(O)C(O)C(O)=C(O)C1C +COS12C=CC=C1N=C1C=CC=CN1C2 +CCCc1ccccc1OC +CC1CC2C3CCC(=C(O)C(O)C(N)=C1C2O)C(O)CC3 +CC1CC2(N1)OCC(=O)C(C)C(=O)C(C(=O)[O-])=C(N)C2O +CC(=O)Oc1ccc(O)c2cccnc12 +COc1c2cccccc-2c2ccccc12 +CC1CCN(c2cc3c(O)c(C(=O)O)cn(C(=O)O)c-3n2)CC1 +[C-]c1cccc[n+]1CCCCCCCCCCCCCCCC +CCCCCCCCCCCCCCCCn1cc(C)cc1C +[C+]CC[N+](C)(C)CCCCCCCCCCCCCCCC +CC(C)CC(C)C(C)(C)NC(=O)N[N+](=O)O +O=C1C=C2C(=O)NC2N1 +CCCCCCCCCCCCCCCC[n+]1ccccc1[N+] +COc1cc2ccccc2c2ccccc12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(C(S)C(=O)O)C(NC(C)C)CSC12 +COc1c(C)c(C)cc(O)c2c(O)c-2c(C)c1C +COC1C(O)C(O)C(O)C(N2CCN3C(O)C(O)C(O)C(O)C(N)C(O)C(O)C(O)C2C(O)C3CO)C(O)C(O)CC1(C)OC +[C-]Sc1cccc[n+]1CCCCCCCCCCCCCCCC +Cc1cc(C)c2cc(C3CCCNCC3)cc-2c(=O)c(C)c1 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCCCCCCCCCCCCCCC[N+](C)(C)Cc1ccccc1[N+] +CC(=S)Oc1ccc([N+](=O)[O-])o1 +Cc1cc(O)c2cccccc1-2 +CC[n+]1ccccc1Oc1ccc(C)cc1C +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CCCCCCC1=CC(C(=O)O)=C2C(=O)SC=C12 +O=C1C=C2CCC2C1O +O=[N+]([O-])c1ncc(O)o1 +COC1C(N)C2OC(OC(C)OC(O)C1O)OC1C(C)C(N)C(N)CC(N)C(CC2O)C(C(=O)O)CC(O)C1O +COC1CN(c2ccc3c(=O)c(C(=O)O)cn(CC(C)C)c3c2)CCN1C +CC1CC(O)C2COOC3(OC2C)C(C)C(O)=C(NC1=O)C(O)C(O)C(O)C(O)CC(O)C(O)CC(O)CC(O)C(O)C(N)C(O)C3O +COc1nc(N)ncc1O +COC1CCC(O)=C(C(N)=O)C(O)C(N)C(O)C(O)C(=O)C1C +CC(N)=C(C(=O)O)N1CSC2NC3C(O)N3C(C)=C(C(=O)O)N3C(=O)N3C(O)C(C(C)C(N)=O)=C(C(=O)[O-])N2C1=O +COP(=O)(O)OO +CN(C)C1C(O)=C(O)C(O)C(O)C1O +CC1=C(C(=O)O)C(=O)CSC(C)C(O)C2=CC(C)C(OO)C(O)C(O)C(O2)C1=O +CC1CC(O)C(O)C(O)C(OC2OC(O)C(O)C(O)C(O)CSC2N)C(O)C(O)C(O)C(N)C(=O)C(O)C(O)C1OCO +COC1C(O)C(O)C(O)C(O)C(O)C(O)OC1(C)OC +O=C1CN(N2C=C3N(Cc4ccccc4)C=C(C(=O)O)C(=O)N3C=N2)C1 +COP(=O)(O)OOOc1ccc(C2CC2)c2cccnc12 +CC(=O)Oc1ccccc1C +CC(=O)Oc1ccc(C)c2cccnc12 +[C-]n1c(O)ccc1OC(C)=O +CCN1C=C2CSC1C(C(=O)N1CCC(C(=O)C(C)C)=C1C(=O)O)NC2=O +CC1COc2ccccc2-c2nccnc21 +Cc1ccc(O)c2ncccc12 +COc1cc(C)cc(O)c2cccc1-2 +COc1cc(C(=O)O)ccc1C +CC(=O)c1ccc([N+](=O)[O-])o1 +CC1CC(N)C(O)C(O)C(O)C(O)C(O)C1O +CC(C)=C(O)C(=O)C1=C(N)C(O)OC(O)CC(C)C(O)C(C)C1O +CCn1cc(C(=O)O)cc1OC +CC1N=NC2=C(O)C3=C(OOO)C(C(=O)O)=CN1C23 +CCCCCCCOc1csc(O)c1OC +CC1CCC2OC(C3C(=O)C(C)NC(C)C3O)C(=O)N2C1 +O=c1cnn(C2CC2)c2ccc(N3CCNCC3)cc12 +CON=C(O)c1ccc(O)c2cccnc12 +COc1c(C)cc(C)cc1O +O=C1C=C2C(O)CC2OC1 +CC1C(O)OC(C)(C)C(O)C(O)C(O)C(O)C(O)C(OO)C1O +COc1c(O)c(C)cc(C)c1O +CCn1cc(C(=O)O)c(=O)c2nc3c(cc21)OCO3 +COC1(C2CC(O)C(N)C(=O)C(O)C(N)C3C(O)C(O)C(O)C3O2)C(C)C(O)C1O +CC(O)CC1C(=O)NCC(C)C(O)C(O)C(O)C1O +CON=C(C(=O)O)c1ccc([N+](=O)[O-])o1 +CCn1cc(C(=O)O)c2cccnc21 +CCCCCCCCCCCCc1ccccc1OC +CON=C(O)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1nc(C)c2ccccc21 +CN(C)CCOC(=O)OC1c2ccccc2-c2ccccc21 +CC(=O)Oc1ccc(C)c2cccnc12 +CCC=CC(O)C(=O)Nc1csc(N)n1 +CON=C(C(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nncn3C)CSC12)c1csc(O)n1 +CO[PH](O)(Br)OOO +CC1C=COC2(C)OC(O)C(O)C(N)C3OC1OC32C +CCC1C(O)C(O)C(O)C(C)C1OC1OC(C)CCOC1O +CCCCCCCCCCCCCCCC[N+](C)(C)CC(C)(C)C[O-] +CC(=O)OC1=CC=C2CSC1C2CC(N)=O +[C-]C[N+](C)(C)CCCCCCCCCCCCCCCC +CCn1cc(C(=O)O)c2c1C(C)(N1CCNCC1)C=C2 +Cc1cc(O)c(CN(C)C)c2ncccc12 +Cc1cc(C)c2cccnc2c1C(=O)O +O=C1C=C2C(O)CC2OC1 +Nc1ccc([N+](=O)[O-])o1 +Cc1cc(C)c2cccnc2c1O +COc1c(C)ccc(C)c1O +CCn1cc(C(=O)O)c2ccc(N3CCNCC3)cc21 +CC1C2CC1C(=O)O2 +[C-][N+]O[N+](C)CCCCCCCCCCCCCCCC +COC(=O)NC1OC2C(=O)C12 +CCn1cc(C)cc(O)c1=O +CCn1cc(C(=O)O)cc1OC +CCn1nc(C(=O)O)c2ccnn21 +CC(=O)OCC1C(N)C(C)=C(C(=O)[O-])NC(=O)C(OC(N)=O)OC(C)C1O +CN(c1ccccc1)c1ccccc1 +O=C(O)OC1C(=O)C(O)C1O diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2 fsr.csv b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2 fsr.csv new file mode 100644 index 0000000000000000000000000000000000000000..047cf9f412ab7d0cd83a03bc61ce2ffd8491b7d5 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2 fsr.csv @@ -0,0 +1,101 @@ +SMILES,Predicted_activity,Probability +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CCOC(=O)NN=Cc1ccccc1,0,0.9972525238990784 +O=[N+]([O-])[O-],0,0.9995403289794922 +Nc1ccccc1[N+]([O-])CO,0,0.9841969609260559 +CCOc1cc(C(=O)[O-])cc2ccccc12,0,0.9976166486740112 +Cn1cnnc1SCC1=C(C(=O)[O-])N2C(=O)NC(N)(c3ccccc3)C2SC1,0,0.9974321722984314 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(CC(C)O)c3c2)CC1,1,0.9077041745185852 +[C-]c1ccccc1NS(C)(=O)=O,0,0.9995831847190857 +CON=C(N)n1cccc1,0,0.9955092668533325 +NC(=O)NN=Cc1ccc([N+](=O)[O-])o1,0,0.8499706983566284 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8795042634010315 +NCn1cccc1,0,0.9944251775741577 +Cc1cc(O)ccc1C(C)(C)O,0,0.9973885416984558 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CN1C=CC(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.5402684211730957 +[C-]c1ccccc1C=NNC(N)=O,0,0.9980906844139099 +[C-]c1ccccc1NC(N)=O,0,0.9995915293693542 +[N+]C(=CC(=O)Nc1ccccc1)CC(=O)[O-],0,0.995033860206604 +CC1CCc2cc3c(=O)c(C(=O)O)cn(C)c3cc2OC1,0,0.6730658411979675 +COc1cc(C2COC(C)C2)cc2ccccc12,0,0.991718053817749 +Cn1cc(C(=O)O)c(=O)c2ccc(N3CCNCC3)cc21,1,0.9283344149589539 +NC(=O)NN=Cc1ccccc1,0,0.9929407835006714 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC(=O)NC1C(=O)CN2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12C,1,0.6234769225120544 +O=C(O)c1ccco1,0,0.9942418932914734 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)CC1,1,0.9370650053024292 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8674365878105164 +CON=C(N)n1cccc1,0,0.9955092668533325 +COc1cc(Oc2ccc(N)cc2)ccc1C,0,0.9924169778823853 +[C-]c1ccccc1C(Br)S(C)(=O)=O,0,0.9983891248703003 +COP(=O)(O)Oc1ccccc1[O-],0,0.9998797178268433 +CNCCCCCCC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12[N+],1,0.9362964034080505 +[N-][C+](=O)[O-],0,0.9994733929634094 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn4c(c2)C4CCN3C)CC1,1,0.5443558692932129 +CC=C1CN(C2=CC=C3C(=O)C(C(=O)O)=CN4SSCC324)C1,0,0.9176252484321594 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8674365878105164 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CCN1C=CC=C(C)C(=O)C(C(=O)[O-])=C1,0,0.9888635873794556 +[C-]c1cccc[n+]1CCCCCCCCCCCCCCCC,0,0.9819117784500122 +O=C1N=Nc2ccccc21,0,0.9990443587303162 +[C-]c1ccccc1[N+]([N-])CCCCCCCCCCCCCCCC,0,0.9959391355514526 +[C-]c1cccc[n+]1CCCCCCCCCCCCCCCC,0,0.9819117784500122 +Cc1ccc(NC(N)=O)cc1,0,0.9997105002403259 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8884478211402893 +[C-]c1ccccc1[N+](CO)CCCCCCCCCCCCCCCC,0,0.9903810620307922 +Cc1ccc(C(=O)[O-])cc1,0,0.9995489716529846 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.9296661019325256 +CON=C(N)n1cccc1,0,0.9955092668533325 +CON=C(C(N)=O)c1ccccc1,0,0.9964597821235657 +O=[N+]([O-])O[N+][SH](=O)([O-])O,0,0.9997084736824036 +CCCCCCCCCCCCCCCC[N+](C)(C)C[O-],0,0.9573307633399963 +[N+]c1ccccc1NC(N)=O,0,0.9994810223579407 +CC(=O)OOC1C(=O)N2C(C(=O)[O-])=C(CSc3nncn3C)CSC12,0,0.8217602372169495 +[C-]c1cc([N+](=O)[O-])ccc1C(C)=O,0,0.9970352649688721 +CC(=O)OCc1ccccc1[N-],0,0.9985560774803162 +Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)C(NC(N)=O)C2SC1,0,0.6834877133369446 +CNc1ccccc1CC(=O)NC1CCN2C3=NC=CC(NC(=O)[O-])=CC3=CC=CC=CC12C,0,0.9988818764686584 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8674365878105164 +[C-]c1ccccc1OS(=N)(=O)O,0,0.9994814991950989 +[N-][N+](=O)c1ccccc1,0,0.9995115995407104 +COP(=O)(OOO)Oc1cc(C)c(C)cc1O[O-],0,0.999679684638977 +CCCCCCCCCC=C(N)n1cccc1,0,0.9821643829345703 +CS(=O)(=O)Oc1ccccc1[N+],0,0.9997511506080627 +CC(=O)OC1C(=O)N2C(C(C)=O)=C(CSc3nnn(N)n3)C2SC1[N+],1,0.8693654537200928 +[C-]c1ccccc1OC(=C)C,0,0.9995083808898926 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1,1,0.8943677544593811 +[C-]c1ccccc1[N+]([O-])OCCCCCCCCCC,0,0.9931005239486694 +[N-]c1ccccc1[N+](=O)[O-],0,0.9976691603660583 +NC(=O)NN=Cc1ccccc1,0,0.9929407835006714 +[C-]c1ccccc1NC(C)(OOO)C(=NO)C(=O)[O-],0,0.9914059638977051 +O=C(O)c1c(O)cc(O)c2cc(N3CCCC3)ccc2c1=O,0,0.9778732061386108 +O=[N+]([O-])CO,0,0.9872778654098511 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8674365878105164 +CCCCCCCCCCCCCCCC[N+](C)[N-],0,0.9330319166183472 +[N+]c1cc(O)ccc1OC(N)=O,0,0.9993712306022644 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8674365878105164 +NC(=O)Nc1ccccc1NC(=O)[O-],0,0.9995793700218201 +CC(=O)OC1=CC=C([N+](=O)[O-])OC=C1[N+],0,0.9798668622970581 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8674365878105164 +CN(C)CC1(C(=O)Nc2ccccc2)C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC21[N+],1,0.6326962113380432 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +O=[N+]([O-])[O-],0,0.9995403289794922 +[C-]c1ccccc1Nc1ccccc1C,0,0.9994431138038635 +O=[N+]([O-])c1ccccc1,0,0.9962822794914246 +NCCCCCCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9311257600784302 +COC1NC(=O)C(C(N)=O)N2C(C(N)=O)=C(CSc3nnnn3C)CSC12,1,0.9098546504974365 +CC1NC(c2csc(N)n2)NS(=O)(=O)N2C(C(=O)O)OC(CSc3nnnn3C)CSC12,1,0.9308521747589111 +CCn1cc(C(=O)[O-])c(=O)c2ccccc21,0,0.8916933536529541 +CS(=O)(=O)c1ccccc1[N+][N+],0,0.999761164188385 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CN1CCN(C2=CC=C3C(=O)C(C(=O)O)=CN4C(CO)C34C2)C1,0,0.9433662295341492 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(Sc4ccccc4)c3c2)CC1,1,0.864554226398468 +COC1NC(=O)N2C(C(=O)[O-])=C(CSC(N)=O)CSC2SC1C,0,0.8988502621650696 +CNC(=O)C(Br)c1ccc(N2CCCCC2)cc1[N+],0,0.8760650157928467 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9265080690383911 +[C-]c1ccccc1OS(C)(=O)=O,0,0.9995951056480408 +[C-]c1ccccc1OP(=O)(OC)OOO,0,0.9996581077575684 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)C1,1,0.9669685959815979 +CN1CCN(C2=CC=C3C(=O)C(C(=O)O)=CN(C4CC4)C32C)C1,0,0.8976994156837463 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2 probab.png b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2 probab.png new file mode 100644 index 0000000000000000000000000000000000000000..fecf239fdce0b9fba08309297c4a14a33d45e532 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2 probab.png differ diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2.png b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2.png new file mode 100644 index 0000000000000000000000000000000000000000..529b991d407334ecbaa0eac9860a87f6539c0997 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter 2.png differ diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_fsr85.smi b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_fsr85.smi new file mode 100644 index 0000000000000000000000000000000000000000..2e7eabac44d2a74eaf278964a407a71eef08ae8b --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_fsr85.smi @@ -0,0 +1,18 @@ +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +NCCCCCCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)CC1 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(Sc4ccccc4)c3c2)CC1 +CNCCCCCCC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12[N+] +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)C1 +CC1NC(c2csc(N)n2)NS(=O)(=O)N2C(C(=O)O)OC(CSc3nnnn3C)CSC12 +Cn1cc(C(=O)O)c(=O)c2ccc(N3CCNCC3)cc21 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(C)=O)=C(CSc3nnn(N)n3)C2SC1[N+] +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(CC(C)O)c3c2)CC1 +COC1NC(=O)C(C(N)=O)N2C(C(N)=O)=C(CSc3nnnn3C)CSC12 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_fsr85.txt b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_fsr85.txt new file mode 100644 index 0000000000000000000000000000000000000000..2e7eabac44d2a74eaf278964a407a71eef08ae8b --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_fsr85.txt @@ -0,0 +1,18 @@ +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +NCCCCCCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)CC1 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(Sc4ccccc4)c3c2)CC1 +CNCCCCCCC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12[N+] +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)C1 +CC1NC(c2csc(N)n2)NS(=O)(=O)N2C(C(=O)O)OC(CSc3nnnn3C)CSC12 +Cn1cc(C(=O)O)c(=O)c2ccc(N3CCNCC3)cc21 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(C)=O)=C(CSc3nnn(N)n3)C2SC1[N+] +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(CC(C)O)c3c2)CC1 +COC1NC(=O)C(C(N)=O)N2C(C(N)=O)=C(CSc3nnnn3C)CSC12 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_gen_fsr.txt b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_gen_fsr.txt new file mode 100644 index 0000000000000000000000000000000000000000..03a6a1ef244912198fb560cd4d9876f2517f5abd --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 2/iter2_gen_fsr.txt @@ -0,0 +1,100 @@ +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCOC(=O)NN=Cc1ccccc1 +O=[N+]([O-])[O-] +Nc1ccccc1[N+]([O-])CO +CCOc1cc(C(=O)[O-])cc2ccccc12 +Cn1cnnc1SCC1=C(C(=O)[O-])N2C(=O)NC(N)(c3ccccc3)C2SC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(CC(C)O)c3c2)CC1 +[C-]c1ccccc1NS(C)(=O)=O +CON=C(N)n1cccc1 +NC(=O)NN=Cc1ccc([N+](=O)[O-])o1 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +NCn1cccc1 +Cc1cc(O)ccc1C(C)(C)O +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1C=CC(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +[C-]c1ccccc1C=NNC(N)=O +[C-]c1ccccc1NC(N)=O +[N+]C(=CC(=O)Nc1ccccc1)CC(=O)[O-] +CC1CCc2cc3c(=O)c(C(=O)O)cn(C)c3cc2OC1 +COc1cc(C2COC(C)C2)cc2ccccc12 +Cn1cc(C(=O)O)c(=O)c2ccc(N3CCNCC3)cc21 +NC(=O)NN=Cc1ccccc1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)CN2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12C +O=C(O)c1ccco1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CON=C(N)n1cccc1 +COc1cc(Oc2ccc(N)cc2)ccc1C +[C-]c1ccccc1C(Br)S(C)(=O)=O +COP(=O)(O)Oc1ccccc1[O-] +CNCCCCCCC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12[N+] +[N-][C+](=O)[O-] +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn4c(c2)C4CCN3C)CC1 +CC=C1CN(C2=CC=C3C(=O)C(C(=O)O)=CN4SSCC324)C1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1C=CC=C(C)C(=O)C(C(=O)[O-])=C1 +[C-]c1cccc[n+]1CCCCCCCCCCCCCCCC +O=C1N=Nc2ccccc21 +[C-]c1ccccc1[N+]([N-])CCCCCCCCCCCCCCCC +[C-]c1cccc[n+]1CCCCCCCCCCCCCCCC +Cc1ccc(NC(N)=O)cc1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +[C-]c1ccccc1[N+](CO)CCCCCCCCCCCCCCCC +Cc1ccc(C(=O)[O-])cc1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CON=C(N)n1cccc1 +CON=C(C(N)=O)c1ccccc1 +O=[N+]([O-])O[N+][SH](=O)([O-])O +CCCCCCCCCCCCCCCC[N+](C)(C)C[O-] +[N+]c1ccccc1NC(N)=O +CC(=O)OOC1C(=O)N2C(C(=O)[O-])=C(CSc3nncn3C)CSC12 +[C-]c1cc([N+](=O)[O-])ccc1C(C)=O +CC(=O)OCc1ccccc1[N-] +Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)C(NC(N)=O)C2SC1 +CNc1ccccc1CC(=O)NC1CCN2C3=NC=CC(NC(=O)[O-])=CC3=CC=CC=CC12C +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +[C-]c1ccccc1OS(=N)(=O)O +[N-][N+](=O)c1ccccc1 +COP(=O)(OOO)Oc1cc(C)c(C)cc1O[O-] +CCCCCCCCCC=C(N)n1cccc1 +CS(=O)(=O)Oc1ccccc1[N+] +CC(=O)OC1C(=O)N2C(C(C)=O)=C(CSc3nnn(N)n3)C2SC1[N+] +[C-]c1ccccc1OC(=C)C +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +[C-]c1ccccc1[N+]([O-])OCCCCCCCCCC +[N-]c1ccccc1[N+](=O)[O-] +NC(=O)NN=Cc1ccccc1 +[C-]c1ccccc1NC(C)(OOO)C(=NO)C(=O)[O-] +O=C(O)c1c(O)cc(O)c2cc(N3CCCC3)ccc2c1=O +O=[N+]([O-])CO +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CCCCCCCCCCCCCCCC[N+](C)[N-] +[N+]c1cc(O)ccc1OC(N)=O +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +NC(=O)Nc1ccccc1NC(=O)[O-] +CC(=O)OC1=CC=C([N+](=O)[O-])OC=C1[N+] +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CN(C)CC1(C(=O)Nc2ccccc2)C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC21[N+] +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +O=[N+]([O-])[O-] +[C-]c1ccccc1Nc1ccccc1C +O=[N+]([O-])c1ccccc1 +NCCCCCCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +COC1NC(=O)C(C(N)=O)N2C(C(N)=O)=C(CSc3nnnn3C)CSC12 +CC1NC(c2csc(N)n2)NS(=O)(=O)N2C(C(=O)O)OC(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)[O-])c(=O)c2ccccc21 +CS(=O)(=O)c1ccccc1[N+][N+] +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(C2=CC=C3C(=O)C(C(=O)O)=CN4C(CO)C34C2)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(Sc4ccccc4)c3c2)CC1 +COC1NC(=O)N2C(C(=O)[O-])=C(CSC(N)=O)CSC2SC1C +CNC(=O)C(Br)c1ccc(N2CCCCC2)cc1[N+] +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +[C-]c1ccccc1OS(C)(=O)=O +[C-]c1ccccc1OP(=O)(OC)OOO +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)C1 +CN1CCN(C2=CC=C3C(=O)C(C(=O)O)=CN(C4CC4)C32C)C1 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 fsr.csv b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 fsr.csv new file mode 100644 index 0000000000000000000000000000000000000000..6c913f29feedcab240c24d5eafed9278c1f88e18 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 fsr.csv @@ -0,0 +1,101 @@ +SMILES,Predicted_activity,Probability +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1,1,0.7803784608840942 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9478779435157776 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9478779435157776 +CCCCCCCCCCCCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.9530841112136841 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8674365878105164 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1,1,0.8943677544593811 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)C12,1,0.8110349774360657 +COC(CCOC(C)C)Cc1ccc(C)cc1C,0,0.9977249503135681 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CCCCCCCCCCCCCCCC[n+]1ccccc1,0,0.9556085467338562 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC1CCc2c(ccc3c(=O)c(C(=O)O)cn(C4CC4)c23)OC1,1,0.5529066324234009 +CCCCCCCCCCC[N+](N)n1cccc1,0,0.9930644631385803 +CCN1C=C(C(=O)[O-])C=C(O)C(C)=C1OC,0,0.9780463576316833 +CC(C)CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9292013645172119 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9265080690383911 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.898070216178894 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8884478211402893 +COC1=CC=C2C=CC=CC21C,0,0.9992515444755554 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC(=O)NNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.911375880241394 +COC1(NC(=O)C2(C(N)=O)C(=O)N2C(C(=O)[O-])=C(C)N)NC(C)C1O,0,0.8850927352905273 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CC(C)OC1C(=O)NN(C)C2SCC(CSc3nnnn3C)=C(C(=O)[O-])N2C1=O,0,0.5072059035301208 +CCCCCCNC(=O)NC1C(=O)N2C(C(=O)O)=C(C3N=NN3C)CSC12,1,0.6930381655693054 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)CC1,1,0.9709779620170593 +CCCC1N2C=C(C)C(OC)=C(O)C(O)=C(O)C(OC)C(O)N12,0,0.9979208111763 +CCCCCCCCCCCCCN(C)Cc1ccccc1OC(C)OC,0,0.9803651571273804 +CCn1c(C)cc(C)c1OC,0,0.9985442161560059 +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)NC(CN)C2SC1,0,0.6936132311820984 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.898070216178894 +CC(=O)OC1=CC=C(C(N)=O)C(=O)N2C(C(=O)O)=C(CSc3nncn3C)CSC12,0,0.5669190287590027 +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9156983494758606 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CS1,1,0.9085196256637573 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8674365878105164 +CCn1nnc(C(=O)O)c1O,0,0.9889017343521118 +CC(=O)Oc1ccc(C)c2ccccc12,0,0.9931873083114624 +CCCCCCCCCCc1cccnc1CC(=O)O,0,0.9365670084953308 +COc1c(C)cc(C)cc1C(C)CN,0,0.9948588609695435 +CC(=O)Oc1ccc(O)c2cccnc12,0,0.9876699447631836 +CC(=O)NC1C(=O)C2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.7738679647445679 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8884478211402893 +CC1C(C)N(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CCN1C,1,0.9340919256210327 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9478779435157776 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)C1,1,0.8111758828163147 +CCCCCCCCCCc1ccc(C)cc1OC,0,0.9815279245376587 +CC1=C(C(=O)O)N2C(=O)N(C(N)=O)C(=O)C3NC(=O)C3CC(=O)NN(C)C12,0,0.9969946146011353 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CS1,1,0.8878125548362732 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +COc1cccnc1OC,0,0.9944906234741211 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)C(NNC(=O)OC(=O)c3csc(N)n3)C2SC1,1,0.8087848424911499 +CC(=O)OC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12,1,0.8708243370056152 +CCCCCCCCCCn1ccoc2cc(c1)C2CCCCC,0,0.9571766257286072 +CCCCCCCCCCCc1ccc(C)nc1O,0,0.976344108581543 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9166659116744995 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +Cc1ccc(Cc2ccccc2[N+])cc1,0,0.9983494281768799 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9478779435157776 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8795042634010315 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.8965586423873901 +CC(C)(C)CCOCCC(NC1=C2C=CC=NC2(CS[N+])C1CCCCCN)C(=O)O,0,0.983128547668457 +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)CC1,1,0.9166994094848633 +COc1c(C)c(C)cc(C)c1O,0,0.9973040819168091 +CC(=O)OC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8494939208030701 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1,1,0.8943677544593811 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cnc(C4CC4)c3c2)CC1,1,0.564960241317749 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CCNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9443836808204651 +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(C)(C)C)C2SC1,1,0.8131334781646729 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9392977356910706 +Cn1ccnc1SCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9300026297569275 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9478779435157776 +Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)C(NC(=O)C(C)(C)C)C2SC1,1,0.7035990357398987 +Cc1cnn(Cc2ccc(N)nc2C)c(=O)c1,0,0.9906898736953735 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CNCCC(O)c1ccc(C)cc1OC,0,0.9957007765769958 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12C,1,0.9216480255126953 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +COc1c(C(C)(C)C)ccc(C)c1C,0,0.9969958066940308 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)C1,1,0.8993147015571594 +CCCCCCCCCCc1cc(C)cnc1C,0,0.9719040393829346 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 fsr85.smi b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 fsr85.smi new file mode 100644 index 0000000000000000000000000000000000000000..d0dec33bccc22c5018d32677e77ba320835d4b58 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 fsr85.smi @@ -0,0 +1,28 @@ +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CS1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)C1 +Cn1ccnc1SCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CS1 +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)CC1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12C +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1C(C)N(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CCN1C +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(C)CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCCCCCCCCCCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CCNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 probab.png b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 probab.png new file mode 100644 index 0000000000000000000000000000000000000000..c5ee9ac95a56f2a729025c174cc693651b9b9993 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3 probab.png differ diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3.png b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3.png new file mode 100644 index 0000000000000000000000000000000000000000..585c68f6b84d85b1ece9613785e9fcb6b2259599 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter 3.png differ diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter3_fsr85.txt b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter3_fsr85.txt new file mode 100644 index 0000000000000000000000000000000000000000..d0dec33bccc22c5018d32677e77ba320835d4b58 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter3_fsr85.txt @@ -0,0 +1,28 @@ +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CS1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)C1 +Cn1ccnc1SCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CS1 +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)CC1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12C +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1C(C)N(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CCN1C +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(C)CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCCCCCCCCCCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CCNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter3_gen_fsr.txt b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter3_gen_fsr.txt new file mode 100644 index 0000000000000000000000000000000000000000..8fe3e4bbf072e484677bcc1afca576ad455dafce --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 3/iter3_gen_fsr.txt @@ -0,0 +1,100 @@ +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCCCCCCCCCCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)C12 +COC(CCOC(C)C)Cc1ccc(C)cc1C +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCCCCCCCCCCCCCC[n+]1ccccc1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCc2c(ccc3c(=O)c(C(=O)O)cn(C4CC4)c23)OC1 +CCCCCCCCCCC[N+](N)n1cccc1 +CCN1C=C(C(=O)[O-])C=C(O)C(C)=C1OC +CC(C)CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +COC1=CC=C2C=CC=CC21C +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COC1(NC(=O)C2(C(N)=O)C(=O)N2C(C(=O)[O-])=C(C)N)NC(C)C1O +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(C)OC1C(=O)NN(C)C2SCC(CSc3nnnn3C)=C(C(=O)[O-])N2C1=O +CCCCCCNC(=O)NC1C(=O)N2C(C(=O)O)=C(C3N=NN3C)CSC12 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)CC1 +CCCC1N2C=C(C)C(OC)=C(O)C(O)=C(O)C(OC)C(O)N12 +CCCCCCCCCCCCCN(C)Cc1ccccc1OC(C)OC +CCn1c(C)cc(C)c1OC +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)NC(CN)C2SC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1=CC=C(C(N)=O)C(=O)N2C(C(=O)O)=C(CSc3nncn3C)CSC12 +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CS1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CCn1nnc(C(=O)O)c1O +CC(=O)Oc1ccc(C)c2ccccc12 +CCCCCCCCCCc1cccnc1CC(=O)O +COc1c(C)cc(C)cc1C(C)CN +CC(=O)Oc1ccc(O)c2cccnc12 +CC(=O)NC1C(=O)C2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1C(C)N(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CCN1C +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)C1 +CCCCCCCCCCc1ccc(C)cc1OC +CC1=C(C(=O)O)N2C(=O)N(C(N)=O)C(=O)C3NC(=O)C3CC(=O)NN(C)C12 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CS1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +COc1cccnc1OC +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)C(NNC(=O)OC(=O)c3csc(N)n3)C2SC1 +CC(=O)OC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CCCCCCCCCCn1ccoc2cc(c1)C2CCCCC +CCCCCCCCCCCc1ccc(C)nc1O +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +Cc1ccc(Cc2ccccc2[N+])cc1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(C)(C)CCOCCC(NC1=C2C=CC=NC2(CS[N+])C1CCCCCN)C(=O)O +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)CC1 +COc1c(C)c(C)cc(C)c1O +CC(=O)OC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cnc(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(NC(=O)C(C)(C)C)C2SC1 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +Cn1ccnc1SCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)C(NC(=O)C(C)(C)C)C2SC1 +Cc1cnn(Cc2ccc(N)nc2C)c(=O)c1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CNCCC(O)c1ccc(C)cc1OC +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12C +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +COc1c(C(C)(C)C)ccc(C)c1C +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN(C)C4)c3c2)C1 +CCCCCCCCCCc1cc(C)cnc1C diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4 gen fsr.csv b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4 gen fsr.csv new file mode 100644 index 0000000000000000000000000000000000000000..b92ece2280e905055c6a581386f83486aa24b3b2 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4 gen fsr.csv @@ -0,0 +1,101 @@ +SMILES,Predicted_activity,Probability +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(OC(N)=O)C2SC1,1,0.5315529108047485 +CC1CCC(=O)NC2C(=O)C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.8901554942131042 +CC1C(CO)OC(C)(C)C2SCC(CSc3nnnn3C)=C(C(=O)O)C(=O)N12,1,0.9339867830276489 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9166659116744995 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9478779435157776 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9331246018409729 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)CC1,1,0.9709779620170593 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9478779435157776 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12,1,0.9110217094421387 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CCCCCCCCCCCCCCCC[N+](C)(C)CC1CC1C,0,0.9556289911270142 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +O=C(O)c1cn(C2CC2)c2cc(C3CCC(O)C3)ccc2c1=O,0,0.7964357733726501 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.898070216178894 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(-c4ccccc4)c3c2)CC1,1,0.7320073843002319 +CC1=C(N)C(=O)C(S(C)(=O)=O)=C1,0,0.9977689981460571 +CCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.889667272567749 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CCC2C(N)CNC1CC(CO)C2C,0,0.9978637099266052 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.7483000159263611 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.9296661019325256 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9265080690383911 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9166659116744995 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9265080690383911 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CNCCCCCCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9647257924079895 +CCOC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8563404083251953 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CCCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9308534264564514 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8884478211402893 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.9296661019325256 +CC(C)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9586541056632996 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC1CCC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.7795932292938232 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8884478211402893 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9478779435157776 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9147716760635376 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8884478211402893 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.9016570448875427 +CC1CC(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.6775283813476562 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +Cn1ncnc1SCC1=C(C(=O)O)N2C(=O)C(NS(C)(=O)=O)C2SC1,0,0.9498425126075745 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.9296661019325256 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CC(=O)OC1C(=O)n2c1nc(N1CCNCC1)c2C(=O)O,0,0.9893285632133484 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8795042634010315 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9331246018409729 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CNC1,1,0.9109234809875488 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CCN1,1,0.8833326101303101 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9392977356910706 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CCCCCCCCCCCCCCCC[N+](C)(C)OC(Br)CC1CC1O,0,0.9697214365005493 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8884478211402893 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9213360548019409 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9265080690383911 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1,1,0.7803784608840942 +CC1CC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1,1,0.7483000159263611 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.9405321478843689 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1,1,0.8832944631576538 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9166659116744995 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4 probab.png b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4 probab.png new file mode 100644 index 0000000000000000000000000000000000000000..5286358efea65f17822dc5ebac14e444c9d0ec3e Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4 probab.png differ diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4fsr.png b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4fsr.png new file mode 100644 index 0000000000000000000000000000000000000000..6c50105c611f0e8a8a80772a5f151ead396a7631 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter 4fsr.png differ diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_fsr85.txt b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_fsr85.txt new file mode 100644 index 0000000000000000000000000000000000000000..476f745ea537d64a3c2dd86be2587a6eb780d052 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_fsr85.txt @@ -0,0 +1,26 @@ +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CNC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CCCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCOC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CNCCCCCCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CCN1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCC(=O)NC2C(=O)C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1C(CO)OC(C)(C)C2SCC(CSc3nnnn3C)=C(C(=O)O)C(=O)N12 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)CC1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(C)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_gen_fsr.smi b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_gen_fsr.smi new file mode 100644 index 0000000000000000000000000000000000000000..0aac2a6ed85277f1fc9dc2d0a6ef4b2647bb2954 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_gen_fsr.smi @@ -0,0 +1,100 @@ +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(OC(N)=O)C2SC1 +CC1CCC(=O)NC2C(=O)C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1C(CO)OC(C)(C)C2SCC(CSc3nnnn3C)=C(C(=O)O)C(=O)N12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCCCCCCCCCCCCCC[N+](C)(C)CC1CC1C +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +O=C(O)c1cn(C2CC2)c2cc(C3CCC(O)C3)ccc2c1=O +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(-c4ccccc4)c3c2)CC1 +CC1=C(N)C(=O)C(S(C)(=O)=O)=C1 +CCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCC2C(N)CNC1CC(CO)C2C +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CNCCCCCCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCOC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(C)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC1CC(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +Cn1ncnc1SCC1=C(C(=O)O)N2C(=O)C(NS(C)(=O)=O)C2SC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)n2c1nc(N1CCNCC1)c2C(=O)O +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CNC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CCN1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCCCCCCCCCCCCCC[N+](C)(C)OC(Br)CC1CC1O +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CC1CC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 diff --git a/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_gen_fsr.txt b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_gen_fsr.txt new file mode 100644 index 0000000000000000000000000000000000000000..0aac2a6ed85277f1fc9dc2d0a6ef4b2647bb2954 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/fsr/iter 4/iter4_gen_fsr.txt @@ -0,0 +1,100 @@ +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(OC(N)=O)C2SC1 +CC1CCC(=O)NC2C(=O)C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1C(CO)OC(C)(C)C2SCC(CSc3nnnn3C)=C(C(=O)O)C(=O)N12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCCCCCCCCCCCCCC[N+](C)(C)CC1CC1C +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +O=C(O)c1cn(C2CC2)c2cc(C3CCC(O)C3)ccc2c1=O +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(-c4ccccc4)c3c2)CC1 +CC1=C(N)C(=O)C(S(C)(=O)=O)=C1 +CCC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCC2C(N)CNC1CC(CO)C2C +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CNCCCCCCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCOC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(C)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +COC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC1CC(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +Cn1ncnc1SCC1=C(C(=O)O)N2C(=O)C(NS(C)(=O)=O)C2SC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)n2c1nc(N1CCNCC1)c2C(=O)O +CN(C)C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CNC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CCN1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCCCCCCCCCCCCCCC[N+](C)(C)OC(Br)CC1CC1O +NC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCOC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C)c3c2)CC1 +CC1CC(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OOC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 diff --git a/Experiments/E. Coli Iteration Outputs/iteration plots.ipynb b/Experiments/E. Coli Iteration Outputs/iteration plots.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..fb88bb4f5900108ce4167608386f0d84d3297724 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/iteration plots.ipynb @@ -0,0 +1,345 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": 2, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Collecting matplotlib\n", + " Downloading matplotlib-3.6.0-cp39-cp39-win_amd64.whl (7.2 MB)\n", + " ---------------------------------------- 7.2/7.2 MB 536.5 kB/s eta 0:00:00\n", + "Collecting kiwisolver>=1.0.1\n", + " Downloading kiwisolver-1.4.4-cp39-cp39-win_amd64.whl (55 kB)\n", + " -------------------------------------- 55.4/55.4 kB 961.1 kB/s eta 0:00:00\n", + "Requirement already satisfied: python-dateutil>=2.7 in c:\\users\\prajwal\\appdata\\roaming\\python\\python39\\site-packages (from matplotlib) (2.8.2)\n", + "Collecting fonttools>=4.22.0\n", + " Downloading fonttools-4.37.4-py3-none-any.whl (960 kB)\n", + " ------------------------------------ 960.8/960.8 kB 950.6 kB/s eta 0:00:00\n", + "Requirement already satisfied: numpy>=1.19 in c:\\users\\prajwal\\appdata\\local\\programs\\python\\python39\\lib\\site-packages (from matplotlib) (1.23.3)\n", + "Collecting cycler>=0.10\n", + " Downloading cycler-0.11.0-py3-none-any.whl (6.4 kB)\n", + "Requirement already satisfied: pillow>=6.2.0 in c:\\users\\prajwal\\appdata\\local\\programs\\python\\python39\\lib\\site-packages (from matplotlib) (9.2.0)\n", + "Requirement already satisfied: packaging>=20.0 in c:\\users\\prajwal\\appdata\\roaming\\python\\python39\\site-packages (from matplotlib) (21.3)\n", + "Collecting contourpy>=1.0.1\n", + " Downloading contourpy-1.0.5-cp39-cp39-win_amd64.whl (161 kB)\n", + " -------------------------------------- 162.0/162.0 kB 2.4 MB/s eta 0:00:00\n", + "Requirement already satisfied: pyparsing>=2.2.1 in c:\\users\\prajwal\\appdata\\roaming\\python\\python39\\site-packages (from matplotlib) (3.0.9)\n", + "Requirement already satisfied: six>=1.5 in c:\\users\\prajwal\\appdata\\roaming\\python\\python39\\site-packages (from python-dateutil>=2.7->matplotlib) (1.16.0)\n", + "Installing collected packages: kiwisolver, fonttools, cycler, contourpy, matplotlib\n", + "Successfully installed contourpy-1.0.5 cycler-0.11.0 fonttools-4.37.4 kiwisolver-1.4.4 matplotlib-3.6.0\n", + "Note: you may need to restart the kernel to use updated packages.\n" + ] + }, + { + "name": "stderr", + "output_type": "stream", + "text": [ + " WARNING: The scripts fonttools.exe, pyftmerge.exe, pyftsubset.exe and ttx.exe are installed in 'c:\\Users\\Prajwal\\AppData\\Local\\Programs\\Python\\Python39\\Scripts' which is not on PATH.\n", + " Consider adding this directory to PATH or, if you prefer to suppress this warning, use --no-warn-script-location.\n" + ] + } + ], + "source": [ + "\n", + "\n", + "\n", + "pip install matplotlib" + ] + }, + { + "cell_type": "code", + "execution_count": 3, + "metadata": {}, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Collecting seaborn\n", + " Downloading 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matplotlib>=3.1->seaborn) (4.37.4)\n", + "Requirement already satisfied: pytz>=2020.1 in c:\\users\\prajwal\\appdata\\local\\programs\\python\\python39\\lib\\site-packages (from pandas>=0.25->seaborn) (2022.2.1)\n", + "Requirement already satisfied: six>=1.5 in c:\\users\\prajwal\\appdata\\roaming\\python\\python39\\site-packages (from python-dateutil>=2.7->matplotlib>=3.1->seaborn) (1.16.0)\n", + "Installing collected packages: seaborn\n", + "Successfully installed seaborn-0.12.0\n", + "Note: you may need to restart the kernel to use updated packages.\n" + ] + } + ], + "source": [ + "pip install seaborn" + ] + }, + { + "cell_type": "code", + "execution_count": 4, + "metadata": {}, + "outputs": [], + "source": [ + "import pandas as pd\n", + "import numpy as np\n", + "import matplotlib.pyplot as plt\n", + "\n", + "import seaborn as sns" + ] + }, + { + "cell_type": "code", + "execution_count": 5, + "metadata": {}, + "outputs": [ + { + "data": { + "text/html": [ + "
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", + "text/plain": [ + "
" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "plt.figure()\n", + "sns.lineplot(x = 'Iteration', y = 'Finetuning FSR', data = df, label = 'FSR', markers='k')\n", + "sns.lineplot(x = 'Iteration', y = 'Finetuning w/o FSR', data = df, label = 'Without FSR', markers='k')\n", + "plt.ylabel('Molecules used for Finetuning')\n", + "plt.title('No. of Molecules used for Finetuning')" + ] + }, + { + "cell_type": "code", + "execution_count": 23, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "Text(0.5, 1.0, 'No. of Molecules predicted to inhibit E.Coli')" + ] + }, + "execution_count": 23, + "metadata": {}, + "output_type": "execute_result" + }, + { + "data": { + "image/png": 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", + "text/plain": [ + "
" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "plt.figure()\n", + "sns.lineplot(x = 'Iteration', y = 'E.Coli Inhibition FSR', data = df, label = 'FSR', markers='o')\n", + "sns.lineplot(x = 'Iteration', y = 'E.Coli Inhibition w/o FSR', data = df, label = 'Without FSR', markers='o')\n", + "plt.ylabel('Molecules predicted to Inhibit E. Coli')\n", + "plt.title('No. of Molecules predicted to inhibit E.Coli')" + ] + }, + { + "cell_type": "code", + "execution_count": 18, + "metadata": {}, + "outputs": [ + { + "data": { + "text/plain": [ + "Text(0.5, 1.0, 'No. of unique Molecules with 85% or more probability ')" + ] + }, + "execution_count": 18, + "metadata": {}, + "output_type": "execute_result" + }, + { + "data": { + "image/png": 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", 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" + ] + }, + "metadata": {}, + "output_type": "display_data" + } + ], + "source": [ + "plt.figure()\n", + "sns.lineplot(x = 'Iteration', y = '>0.85 FSR', data = df, label = 'FSR')\n", + "sns.lineplot(x = 'Iteration', y = '>0.85 w/o FSR', data = df, label = 'Without FSR')\n", + "plt.ylabel('Unique molecules with >0.85 probab')\n", + "plt.title('No. of unique Molecules with 85% or more probability ')" + ] + } + ], + "metadata": { + "kernelspec": { + "display_name": "Python 3.9.5 64-bit", + "language": "python", + "name": "python3" + }, + "language_info": { + "codemirror_mode": { + "name": "ipython", + "version": 3 + }, + "file_extension": ".py", + "mimetype": "text/x-python", + "name": "python", + "nbconvert_exporter": "python", + "pygments_lexer": "ipython3", + "version": "3.9.5" + }, + "orig_nbformat": 4, + "vscode": { + "interpreter": { + "hash": "a4329ea539b1232b51730207fd9c93849c82cf9ff2a2d6356a1e6b85d15167f8" + } + } + }, + "nbformat": 4, + "nbformat_minor": 2 +} diff --git a/Experiments/E. 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Coli Iteration Outputs/non fsr/iter 1/iter1_gen_norm.txt @@ -0,0 +1,100 @@ +COC1=CC=C(C(=O)O)C(=O)C2=CN(F)C(N3CCN(C)CC3)=CC12Cl +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +COc1ccc(Cl)c2ccccc12 +COC1CC(C(=O)O)C(=O)C2C(C(=O)O)=C(CCc3nnnn3C)CSC12 +CCc1cc(C(=O)O)c(=O)c2cn(F)c(N3CCNCC3)cc1-2 +Nc1ccccc1Cc1ccccc1Cc1ccccc1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCCCNCC3)cc21 +Oc1cc(Cl)c(Cl)c2cccnc12 +COc1cc(C(=O)O)c(=O)c2cn(F)c(N3CCNCC3)cc1-2 +Oc1cc(Cl)c(Cl)c2cc(F)c(N3CCNCC3)nc12 +[N-]c1ccc(Cl)c2cccnc12 +CC1CC2CCCC(CN(C)C)C2SCC(C(N)=O)C(=O)N1c1ccccc1Cl +Nc1nnc(Cl)c2cc(F)c(N3CCNCC3)cc12 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc12 +COCCCCCC(C)C1C(=O)C2C(=O)C3CC1(Cl)C(OC)C2C3C(=O)O +CCN1C=C(C(=O)O)C(=O)c2cc3c(c1c2Cl)C=C(OC)OCCC3 +CCCCCCCCCCCCCCCCCCCCC[N+](C)(O)Cc1ccccc1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +Oc1cc(Cl)c(Cl)c2ccccc12 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +COc1cc(C(=O)O)c(=N)n2cccnc1C=CC=C(Cl)C=C2Cl +CCc1ccc(Cl)c2cc(F)c(N3CCNCC3)c(F)c2c1=O +CC1CC(c2ccccc2)C(=O)OCC2=C(c3cnnn3C)CCSC21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +COc1cc(C2CCCCCCCCCCCCCC[N+](C)(C)C2)c(Cl)cc1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(C)C1=C2C(=CC(F)=C2N2CCNCC2)C(=O)C(C(=O)O)=C1 +Oc1ccc(Cl)c2cccnc12 +Oc1ccc(Cl)c2cccnc12 +COc1cc(Cl)c(CN)c2nc(F)c(N3CCCCNCC3)cc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(C3CCNCC3)cc21 +Cc1cc(C(=O)O)c(=O)c2cn(F)c(N3CCNCC3)cc1-2 +OCc1c(O)c(O)cc(Cl)c1Cl +CC(C)C1c2ccccc21 +CN1CCN(c2ccc([N+](=O)[O-])o2)C(=O)N1 +CCC1C=C(C(=O)O)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +Oc1ccc(Cl)c2cc(F)c(C3CCNCC3)nc12 +CC(C=Cc1ccc(Cl)cc1Oc1ccc(C(=O)O)cc1)Cc1ccc(Cl)nc1 +CNCCCC(C(=O)O)C(=O)c1cc(F)c(N2CCN(C)CC2)cc1Cl +CC(Cc1ccccc1[O-])[N+](CO)CCCCCCCCCCCCCCCCCCCCCCCC(C)(C)C +CCn1cc(C(=O)O)c(=O)c2cn(N3CCNCC3)c(F)c2c1=O +Oc1cc(Cl)c(Cl)c2cccnc12 +Oc1c(F)c(Cl)cc2cccnc12 +Oc1c(Cl)cc(Cl)c2ccccc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(C3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(C3CCNCC3)nc21 +Cc1cc(Cl)c(Cl)c2ccccc12 +Oc1ccc(Cl)c2ccccc12 +Cc1cc(Cl)c2cc(F)c(N3CCNCC3)cc2c1C +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC(C)(C)c1ccc(C(=O)O)c(=O)c2cnc(N3CCNCC3)nc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +COc1ccc(Cl)c2cc(F)c(N3CCN(C)CC3)c(O)c2c1=O +CCn1cc(C(=O)O)c(=O)c2cc(F)c(O)c(N3CCNCC3)c21 +CCn1cc(C(=O)O)c(=O)c2cn(C3CC3)c(F)c2c1=O +Oc1c(Cl)cc(Cl)c2cccnc12 +CNC1=CC2=C(F)C=C(C=CCC3CCCCN23)C(=O)C(C(=O)O)=C1 +CCn1cc(C(=O)O)c(=O)c2c(F)c(Cl)c(N3CCNCC3)cc21 +COc1cc(C(=O)O)c(=O)c2cn(F)c(N3CCCCC3)cc1-2 +C=C1c2c(cn(N3CCNCC3)c2F)C(=O)C(C(=O)O)=CN1CC +CCCC(C)CC1CCCC1c1cc(OC)nc(N)c1O +CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC(C)CCCCc1cncnc1CCC=O +Oc1ccc(Cl)c2cccnc12 +COc1cc(C(=O)O)c(=O)c2cc(F)c(F)c(N3CCNCC3)nc1-2 +COc1cc(Cl)c(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc12 +CCn1cc(C(=O)O)c(=O)c2cn(C3CCNCC3)c(N)c21 +CON1CCN(C2=CC3=CC=CC(=O)C(C(=O)O)=CN(C4CC4)C3=C2F)CSC1 +Nc1c(Cl)c(Cl)c(O)c2nc(C3CCNCC3)c(F)nc12 +CC(=O)OC1C(=O)C2C(C(=O)[O-])=C(Cc3ccnn3C)CSC12 +CCN1C=C(C(=O)O)C(=O)C2=CN(F)C(N3CCNCC3)=CN21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +Cn1nnnc1SCC1=C(C(=O)O)CN2C(=O)C3NC(=O)C3=CC(=O)C2S1 +COc1ccc(Cc2cnc(N)nc2N)cc1Oc1ccc(Cl)c2ccccc12 +CCn1cc(C(=O)O)c(=O)c2nc(F)c(N3CCNCC3)cc21 +Cc1cn(C(=O)O)c(=O)c2cc(F)c(N3CCNCCNCC3)cc12 +Cc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc12 +CCN1C=C(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +Oc1ccc2c(n1)C=CC=CC=C2 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +Oc1cc(Cl)c(Cl)c2cccnc12 +CCn1cc(C(=O)O)c(=O)c2cc3c(cc21)OCOC3COCl +CC1=CC=C(O)C2=C(C)C(N3CCNCC3)=C(F)C12Cl +Oc1cc(F)c(Cl)c2cccnc12 +Oc1cc(Cl)c(Cl)c2cccnc12 +CCn1cc(C(=O)O)c(=O)c2cc(Cl)c(N3CCN(C)CC3)nc21 +Cc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCNCC3)c(F)c12 +Cc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c12 +Cc1cc(Cl)c(Cl)c2cccnc12 +CC(=O)Oc1ccc(Cl)c2nncnc12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +Cc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CNCC=C(C(=O)c1ccc(F)cc1)C1=CC=CC(C(=O)O)=CN1C +CCn1cc(C(=O)O)c(=O)c2cnn(N3CCCCC3)c21 +COc1cccc2cc(F)c(N3CCCNCC3)cc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm.csv b/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm.csv new file mode 100644 index 0000000000000000000000000000000000000000..66b60f0b5e4fee48964aed81535f134dd630eab3 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm.csv @@ -0,0 +1,101 @@ +SMILES,Predicted_activity,Probability +COC1=CC=C(C(=O)O)C(=O)C2=CN(F)C(N3CCN(C)CC3)=CC12Cl,0,0.7534972429275513 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21,1,0.9471038579940796 +COc1ccc(Cl)c2ccccc12,0,0.9898338317871094 +COC1CC(C(=O)O)C(=O)C2C(C(=O)O)=C(CCc3nnnn3C)CSC12,0,0.7465823292732239 +CCc1cc(C(=O)O)c(=O)c2cn(F)c(N3CCNCC3)cc1-2,1,0.7548410892486572 +Nc1ccccc1Cc1ccccc1Cc1ccccc1Cl,0,0.9911393523216248 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCCCNCC3)cc21,1,0.8029767870903015 +Oc1cc(Cl)c(Cl)c2cccnc12,0,0.8724346160888672 +COc1cc(C(=O)O)c(=O)c2cn(F)c(N3CCNCC3)cc1-2,1,0.7651128172874451 +Oc1cc(Cl)c(Cl)c2cc(F)c(N3CCNCC3)nc12,1,0.8480020761489868 +[N-]c1ccc(Cl)c2cccnc12,0,0.8830915093421936 +CC1CC2CCCC(CN(C)C)C2SCC(C(N)=O)C(=O)N1c1ccccc1Cl,0,0.9468207955360413 +Nc1nnc(Cl)c2cc(F)c(N3CCNCC3)cc12,1,0.8933462500572205 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9317389726638794 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+Cc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12,1,0.8478049635887146 +CNCC=C(C(=O)c1ccc(F)cc1)C1=CC=CC(C(=O)O)=CN1C,0,0.9931601285934448 +CCn1cc(C(=O)O)c(=O)c2cnn(N3CCCCC3)c21,1,0.5361437201499939 +COc1cccc2cc(F)c(N3CCCNCC3)cc12,0,0.9295026659965515 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm85.smi b/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm85.smi new file mode 100644 index 0000000000000000000000000000000000000000..62a2ba8f5ec5b41919b7983927d773d682c313a2 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm85.smi @@ -0,0 +1,18 @@ +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(Cl)c(N3CCN(C)CC3)nc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cn(C3CCNCC3)c(N)c21 +CCn1cc(C(=O)O)c(=O)c2c(F)c(Cl)c(N3CCNCC3)cc21 +CCN1C=C(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCC1C=C(C(=O)O)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(O)c(N3CCNCC3)c21 +C=C1c2c(cn(N3CCNCC3)c2F)C(=O)C(C(=O)O)=CN1CC +Cn1nnnc1SCC1=C(C(=O)O)CN2C(=O)C3NC(=O)C3=CC(=O)C2S1 +Nc1nnc(Cl)c2cc(F)c(N3CCNCC3)cc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CCn1cc(C(=O)O)c(=O)c2nc(F)c(N3CCNCC3)cc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm85.txt b/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm85.txt new file mode 100644 index 0000000000000000000000000000000000000000..62a2ba8f5ec5b41919b7983927d773d682c313a2 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 1/iter1_norm85.txt @@ -0,0 +1,18 @@ +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(Cl)c(N3CCN(C)CC3)nc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cn(C3CCNCC3)c(N)c21 +CCn1cc(C(=O)O)c(=O)c2c(F)c(Cl)c(N3CCNCC3)cc21 +CCN1C=C(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCC1C=C(C(=O)O)C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(O)c(N3CCNCC3)c21 +C=C1c2c(cn(N3CCNCC3)c2F)C(=O)C(C(=O)O)=CN1CC +Cn1nnnc1SCC1=C(C(=O)O)CN2C(=O)C3NC(=O)C3=CC(=O)C2S1 +Nc1nnc(Cl)c2cc(F)c(N3CCNCC3)cc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CCn1cc(C(=O)O)c(=O)c2nc(F)c(N3CCNCC3)cc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 2/iter 2 norm gen.txt b/Experiments/E. Coli Iteration Outputs/non fsr/iter 2/iter 2 norm gen.txt new file mode 100644 index 0000000000000000000000000000000000000000..52e13b989b73aaa4a0190a469d8648c0f0f89c75 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 2/iter 2 norm gen.txt @@ -0,0 +1,100 @@ +CCn1cc(C(=O)O)c(=O)c2c(F)c(N3CCNCC3)n(F)c21 +CC(=O)OCc1ccc(Cl)cc1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +Oc1cnc(Cl)c2ccccc12 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +NCC1CC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CO1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCC1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc2c(N3CCNCC3)c(F)cc-2c(=O)c(C(=O)O)c1 +CSn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN(C)C1C(=O)N2C(C(=O)O)=C(Cc3nnnn3C)CSC12 +COC1CN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(CO)OC1C(=O)C2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +C=C(C)Oc1ccc(CC(=O)O)cc1Cl +COc1ccc(Cc2cnc(N)nc2)cc1C +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc12 +CC(N)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCC(O)COc1ccccc1[N+](=O)[O-] +O=C(O)CCC12C=CC=CC1=C2O +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)nc21 +CC(CNCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12)c1csc(N)n1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +Oc1c(Cl)cc(Cl)cc1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CO1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +C=C1C(C(=O)O)=CN(CC)c2cc(N3CCNCC3)c(F)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC(C)(C)Cc1ccc(C(O)(F)F)c(F)c1Cl +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC1CCCCCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +Cc1cc(Cl)cc(Cl)c1C(=O)CC(C)C +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +COC1=CC(Cl)=CC(O)=C2C=CC=CC12Cl +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC(C)CCCCCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(C3CCNCC3)n(F)c21 +CC1CC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21 +CCN1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +NC1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +O=C1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCN1C=C(C(=O)O)C(=O)C2=CC(F)=C(N3CCNCC3)N(N)N21 +Cc1cc(O)c(Cl)cc1Cl +Cc1cc(Cl)ccc1OCc1cccc(Cl)c1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)Oc1ccc([N+](=O)[O-])o1 +CN(C)c1ccc([N+](=O)[O-])o1 +Cc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC(=O)Oc1ccc(Cl)c2ccccc12 +Cc1ccccc1OCc1ccc(Cl)cc1Cl +Cc1c(N2CCN(C)CC2)c(F)cc2c(=O)c(C(=O)O)cn(C3CC3)c12 +CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C)CC1 +Cc1cc(C(C)(C)C)c(O)cc1OCOc1c(Cl)cc(Cl)cc1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCCCCCCCCCCC[N+](C)(C)Cc1ccccc1[S-] +O=C1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)NC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +NCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 2/iter 2 norm.csv b/Experiments/E. Coli Iteration Outputs/non fsr/iter 2/iter 2 norm.csv new file mode 100644 index 0000000000000000000000000000000000000000..b7eea865948aef95725e5b49b51947d5da31f8c1 --- /dev/null +++ b/Experiments/E. 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Coli Iteration Outputs/non fsr/iter 2/iter2_norm85.txt b/Experiments/E. Coli Iteration Outputs/non fsr/iter 2/iter2_norm85.txt new file mode 100644 index 0000000000000000000000000000000000000000..fc55c22e48c9e30aa7959ac464bae8905b2aa8d7 --- /dev/null +++ b/Experiments/E. 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Coli Iteration Outputs/non fsr/iter 3 correction/iter 3 gen.csv b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3 gen.csv new file mode 100644 index 0000000000000000000000000000000000000000..10663cdb23821e53a584c032c74a8540e06f85dd --- /dev/null +++ b/Experiments/E. 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+CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CS1,1,0.9475189447402954 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21,1,0.9693030118942261 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.8850416541099548 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCn1nc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.890222430229187 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21,1,0.9693030118942261 +CCn1cc(C(O)NO)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.8864554166793823 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9331246018409729 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1,1,0.9423315525054932 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21,1,0.9392331838607788 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21,1,0.9693030118942261 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3 norm gen.txt b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3 norm gen.txt new file mode 100644 index 0000000000000000000000000000000000000000..04395ada8fa8f4dffcd39960066c9c19f1265910 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3 norm gen.txt @@ -0,0 +1,100 @@ +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCNCCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CCC1CCCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(O[SH](C)(=O)OO)C2SC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CC1=CCCCC(=O)C2SCC(CSc3nnnn3C)=C(C(=O)O)N2C1=O +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(Cc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CON=C1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC(NO)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN(C)C1C2SCC(CSc3nnnn3C)=C(C(=O)O)N2C(=O)[N+]1(C)C +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +C=C1C=C(C(=O)O)C(=O)c2cc(F)c(N3CCNCC3)cc21 +COC1CCC(Cc2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +COc1cn(CC(=O)O)c(=O)c2nc(F)c(N3CCNCC3)cc12 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN(C)C1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)Oc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +Cc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +COC1=C2C=C(N3CCNCC3)C(F)=C2C(=O)C(C(=O)O)=C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(OS(C)(=O)=O)C2SC1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CO[PH](=O)(=O)Nc1ccc([N+](=O)[O-])o1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2nc(F)c(N3CCNCC3)nc21 +CC(=O)OC1=CC(O)=C2C1=CC(N1CCNCC1)=C2O +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +Cn1ncc(C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nnnn4C)CSC23)n1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CS1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1nc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CCn1cc(C(O)NO)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3 probab.png b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3 probab.png new file mode 100644 index 0000000000000000000000000000000000000000..8e6a298a77cf1dec97b2b55b7c2210795358a616 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3 probab.png differ diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3.png b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3.png new file mode 100644 index 0000000000000000000000000000000000000000..56bc27b84f48f6ad5051a91aa57a9d92ba88fdf4 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter 3.png differ diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter3_norm85.smi b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter3_norm85.smi new file mode 100644 index 0000000000000000000000000000000000000000..4b1be01c168fcf9d19f8cdf3d6e0241db6cdd2b4 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter3_norm85.smi @@ -0,0 +1,33 @@ +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CON=C1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1nc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(Cc3nnnn3C)CSC12 +CCn1cc(C(O)NO)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +Cn1ncc(C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nnnn4C)CSC23)n1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(NO)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCNCCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2nc(F)c(N3CCNCC3)nc21 +CCC1CCCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COc1cn(CC(=O)O)c(=O)c2nc(F)c(N3CCNCC3)cc12 +COC1CCC(Cc2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CS1 +CC(=O)OC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter3_norm85.txt b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter3_norm85.txt new file mode 100644 index 0000000000000000000000000000000000000000..4b1be01c168fcf9d19f8cdf3d6e0241db6cdd2b4 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3 correction/iter3_norm85.txt @@ -0,0 +1,33 @@ +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CON=C1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1nc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(Cc3nnnn3C)CSC12 +CCn1cc(C(O)NO)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CNC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +Cn1ncc(C(=O)NC2C(=O)N3C(C(=O)O)=C(CSc4nnnn4C)CSC23)n1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(NO)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCNCCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2nc(F)c(N3CCNCC3)nc21 +CCC1CCCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COc1cn(CC(=O)O)c(=O)c2nc(F)c(N3CCNCC3)cc12 +COC1CCC(Cc2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CS1 +CC(=O)OC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)c(F)c21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 3/iter 3 norm gen.txt b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3/iter 3 norm gen.txt new file mode 100644 index 0000000000000000000000000000000000000000..730bb74f2abe8f5fc956dfa8af79c764339a1361 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3/iter 3 norm gen.txt @@ -0,0 +1,100 @@ +CCN1C=C(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 + +CC(C)(C)c1nc(N)c2cc(C3CCNCC3)n(F)cc-2c1=O +CC1CCC1c1c(N)cc2c(=O)c(C(=O)O)cn(C3CC3)c2c1F +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc12 +CC1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 + +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 + +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +O=C1C=C(Cl)C=C1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 + +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1=C(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)Oc1ccc(Cl)cc1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 + +CC(=O)Oc1ccc(Cl)c(Cl)c1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 + +CN1CNC(=O)C2C(C(=O)O)=C(CSc3nnnn3C)CSC21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 + +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COc1ccc(C(C)(C)CCC(=O)C(C)(C)C)cc1O +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 + +O=C1CCOC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 + + +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 + +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 + +COC1C2=CC(C3CCNCC3)=C21 + +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 + +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 + + +CC1CN=C(C(=O)O)C(=O)c2cc(F)c(N3CCNCC3)nc21 + +Nc1nnnn1CCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)OC1C(=O)C2C(C(=O)O)=C(CSc3nnnn3C)CSC12 + +CCN1C=CC=C(O)c2ccc(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 + +CCC1C=C(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21 +CC(N)CC(=O)CCCC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 + + +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 + +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)SSC12 + +CC1CC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)=N1 + +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 + +CC(C)OCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 + +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 + diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 3/iter 3 norm.csv b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3/iter 3 norm.csv new file mode 100644 index 0000000000000000000000000000000000000000..43b9f355132cf4fcbd9ef213cbe1521d858f48c4 --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 3/iter 3 norm.csv @@ -0,0 +1,101 @@ +SMILES,Predicted_activity,Probability +CCN1C=C(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9495472311973572 +,0,0.9988452196121216 +CC(C)(C)c1nc(N)c2cc(C3CCNCC3)n(F)cc-2c1=O,0,0.8454850316047668 +CC1CCC1c1c(N)cc2c(=O)c(C(=O)O)cn(C3CC3)c2c1F,1,0.8438567519187927 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9317389726638794 +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc12,1,0.615841269493103 +CC1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.8531956076622009 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9565858244895935 +,0,0.9988452196121216 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9512959718704224 +CCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9357052445411682 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +,0,0.9988452196121216 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +O=C1C=C(Cl)C=C1Cl,0,0.988903820514679 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCN(C)CC3)cc21,1,0.9392331838607788 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +,0,0.9988452196121216 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CC1=C(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9120402932167053 +CC(=O)Oc1ccc(Cl)cc1Cl,0,0.9858869910240173 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +,0,0.9988452196121216 +CC(=O)Oc1ccc(Cl)c(Cl)c1Cl,0,0.999046266078949 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +,0,0.9988452196121216 +CN1CNC(=O)C2C(C(=O)O)=C(CSc3nnnn3C)CSC21,1,0.6624380946159363 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +,0,0.9988452196121216 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +CC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9104276895523071 +COc1ccc(C(C)(C)CCC(=O)C(C)(C)C)cc1O,0,0.9953214526176453 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +,0,0.9988452196121216 +O=C1CCOC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.7212211489677429 +,0,0.9988452196121216 +,0,0.9988452196121216 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9512959718704224 +,0,0.9988452196121216 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9317389726638794 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1,1,0.9673447012901306 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9317389726638794 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CC(=O)CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9166823625564575 +,0,0.9988452196121216 +COC1C2=CC(C3CCNCC3)=C21,0,0.997317373752594 +,0,0.9988452196121216 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +,0,0.9988452196121216 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9559361338615417 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9530918002128601 +,0,0.9988452196121216 +,0,0.9988452196121216 +CC1CN=C(C(=O)O)C(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.6936272382736206 +,0,0.9988452196121216 +Nc1nnnn1CCC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9763588905334473 +CC(=O)OC1C(=O)C2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.7527074813842773 +,0,0.9988452196121216 +CCN1C=CC=C(O)c2ccc(N3CCNCC3)nc21,0,0.5349985957145691 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +,0,0.9988452196121216 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Coli Iteration Outputs/non fsr/iter 4 common/iter 4 norm gen.csv b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4 norm gen.csv new file mode 100644 index 0000000000000000000000000000000000000000..35fb6f257d00f85883814eed752ee3523e232711 --- /dev/null +++ b/Experiments/E. 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+CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.927137017250061 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12,1,0.9331246018409729 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.8850416541099548 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21,1,0.9521006941795349 +[O-]c1nn(C2CCNC2)cc1OO,0,0.9922794103622437 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9512959718704224 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21,1,0.9484897255897522 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)nc21,1,0.9339983463287354 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2F)C1,1,0.9777566194534302 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1,1,0.9512959718704224 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4 norm gen.txt b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4 norm gen.txt new file mode 100644 index 0000000000000000000000000000000000000000..a2489d624fe993a81591a143ec25641c1f9d155b --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4 norm gen.txt @@ -0,0 +1,100 @@ +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCCCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(CO)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +Cn1nnnc1SCC1=C(C(=O)[O-])N2C(=O)C(NC(N)=O)C2SC1 +Cn1nnnc1SCC1=C(C(=O)O)N2C(=O)C(=O)C2SC1 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)n21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)N1 +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CC(C)N1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC21 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CSn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN(C)C1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CNC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +O=C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CCC1=C(C(=O)O)C(=O)c2c1nc(N1CCNCC1)c(F)c2F +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CN(C)C1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CON1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +Clc1cc(Cl)n2cccc2c1Cl +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CN(C)C1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +[O-]c1nn(C2CCNC2)cc1OO +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)nc21 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2F)C1 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4 probab.png b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4 probab.png new file mode 100644 index 0000000000000000000000000000000000000000..deb8ab15b2033d97ecd4f94ada203135ed68e9c8 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4 probab.png differ diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4.png b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4.png new file mode 100644 index 0000000000000000000000000000000000000000..0c3396980822759d1ada16674a6b375b42d59d85 Binary files /dev/null and b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter 4.png differ diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter4_norm85.smi b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter4_norm85.smi new file mode 100644 index 0000000000000000000000000000000000000000..1c131090e46eafa397c8cbdbbe370762a895014f --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter4_norm85.smi @@ -0,0 +1,35 @@ +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CN1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)N1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)nc21 +CN(C)C1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CSn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)cc21 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CON1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +CC(CO)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)CC1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CNC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +O=C1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CCN4)c3c2F)C1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 diff --git a/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter4_norm85.txt b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter4_norm85.txt new file mode 100644 index 0000000000000000000000000000000000000000..1c131090e46eafa397c8cbdbbe370762a895014f --- /dev/null +++ b/Experiments/E. Coli Iteration Outputs/non fsr/iter 4 common/iter4_norm85.txt @@ -0,0 +1,35 @@ +CC(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CN(C)C1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CC(=O)NC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +COc1ccc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc12 +CN1CCC(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)N1 +CC1CCN(c2c(F)cc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)nc21 +CN1CCN(c2cc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)CC1 +Cn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +COn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CNC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCn1cc(C(=O)O)c(=O)c2c(F)c(F)c(N3CCNCC3)nc21 +CN(C)C1C(=O)N2C(C(=O)O)=C(COc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2)CC1 +CCN1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CN(C)C1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 +CC1CCN(c2ccc3c(=O)c(C(=O)O)cn(C4CC4)c3c2F)C1 +CC(=O)NC1C(=O)N2C(C(=O)[O-])=C(CSc3nnnn3C)CSC12 +CCn1cc(C(=O)O)c(=O)c2cc(F)c(N3CCNCC3)cc21 +CC(=O)OC1C(=O)N2C(C(=O)O)=C(CSc3nnnn3C)CSC12 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(additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +31,11,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH],Valid +32,7,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +33,5,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O,Valid +34,2,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN,Valid +35,5,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O,Valid +36,6,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC,Valid +37,18,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +38,8,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O,Valid +39,10,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O,Valid +40,11,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O,Valid +41,8,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +42,5,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O,Valid +43,5,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S,Valid +44,18,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +45,7,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl,Valid +46,5,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1,Valid +47,7,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O,Valid +48,10,Primary alkyl amines,[CH2][NH2],[CH2][NH2],Valid +49,18,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3],Valid +50,20,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1,Valid +51,22,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +52,13,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1,Valid +53,19,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21,Valid +54,7,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +55,7,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC,Valid +56,4,Thiocyanates,[SX2][CX2]#[NX1],N#CS,Valid +57,21,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O,Valid +58,12,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +59,6,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O,Valid +60,6,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C,Valid +61,6,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N,Valid +62,12,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C,Valid +63,7,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S,Valid +64,7,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S,Valid +65,2,Peroxides,[OX2][OX2],OO,Valid +66,2,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS,Valid +67,4,Nitroso,[#6][NX2]=[OX1],CN=O,Valid +68,4,N-Nitroso,[#7][NX2]=[OX1],NN=O,Valid +69,5,Azo,[#6][NX2]=[NX2][#6],CN=NC,Valid +70,5,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC,Valid +71,5,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C,Valid +72,6,Hydroxylamines,[OH1][NX3][#6],CN[OH],Valid +73,3,Aminals,N[CX4]N,NCN,Valid +74,12,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C,Valid +75,9,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C,Valid +76,9,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O,Valid +77,9,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O,Valid +78,9,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C,Valid +79,10,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O,Valid +80,6,Acrylonitriles,[NX1]#CC=C,C=CC#N,Valid +81,12,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O,Valid +82,14,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1,Valid +83,5,Ketenes,[CX3]=[CX2]=[OX1],C=C=O,Valid +84,5,Allenes,C=C=C,C=C=C,Valid +85,5,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1,Valid +86,5,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1,Valid +87,5,Aziridines,[CX4]1[NX3][CX4]1,C1CN1,Valid +88,6,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1,Valid +89,6,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1,Valid +90,6,Selen in chain,[Sev2X2],[SeH2],Valid +91,12,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O,Valid +92,12,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N,Valid +93,4,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O,Valid +94,7,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S,Valid +95,7,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S,Valid +96,7,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S,Valid +97,7,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S,Valid +98,11,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O,Valid +99,1,Positively charged N-heterocycles,[#7v4X3R],N,Valid +100,18,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH],Valid +101,20,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1,Valid +102,22,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1,Valid +103,25,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1,Valid +104,27,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1,Valid +105,18,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12,Valid +106,12,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl,Valid +107,12,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O,Valid +108,13,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC,Valid +109,13,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC,Valid +110,9,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O,Valid +111,6,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N,Valid +112,11,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C,Valid +113,10,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O,Valid +114,10,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C,Valid +115,12,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH],Valid +116,12,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C,Valid +117,9,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C,Valid +118,2,Iodine,II,II,Valid +119,8,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H],Valid +120,3,Sulfoxides,[Sv4X3](=[OX1]),O=S,Valid +121,2,Sulfenyl iodides,[SX2][IX1],SI,Valid +122,4,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS,Valid +123,8,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S,Valid +124,8,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS,Valid +125,7,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH],Valid +126,41,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1,Valid +127,5,Organotin compounds,[Sn][#6],C[Sn],Valid +128,8,β-Lactones,C1C(=O)OC1,O=C1CCO1,Valid +129,8,Thio-lactones,C1C(=O)SC1,O=C1CCS1,Valid +130,10,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC,Valid +131,26,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH],Valid +132,14,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1,Valid +133,11,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2],Valid +134,14,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1,Valid +135,11,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1,Valid +136,5,Sulfuranes,C1[SX2]C1,C1CS1,Valid +137,11,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1,Valid +138,12,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O,Valid +139,8,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O,Valid +140,16,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl,Valid +141,17,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C,Valid +142,18,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C,Valid +143,39,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH],Valid +144,19,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH],Valid +145,15,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1,Valid +146,30,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21,Valid +147,11,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O,Valid +148,24,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O,Valid +149,20,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1,Valid +150,7,Furans,c1ccc[oX2]1,c1ccoc1,Valid +151,7,Thiophenes,c1ccc[sX2]1,c1ccsc1,Valid +152,17,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O,Valid +153,10,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH],Valid +154,4,Thioles,[Sv2X2H1],[SH],Valid +155,8,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O,Valid +156,11,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH],Valid +157,1,Phosphorus,P,P,Valid +158,6,Selen,[Se],[SeH2],Valid +159,1,Bor,B,B,Valid +160,6,Silicium,[Si],[SiH4],Valid +161,3,Thione,[CX3]=[SX1!R],C=S,Valid +162,9,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH],Valid +163,7,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S,Valid +164,25,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2],Valid +165,12,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O,Valid +166,16,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1,Valid +167,16,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1,Valid +168,16,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1,Valid +169,16,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1,Valid +170,17,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1,Valid +171,6,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O,Valid +172,6,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N,Valid +173,16,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O,Valid +174,10,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N,Valid +175,12,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S,Valid +176,34,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12,Valid +177,40,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O,Valid +178,16,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH],Valid +179,2,N-N Single bound not in a ring,[N!R][N!R],NN,Valid +180,11,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC,Valid +181,10,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O,Valid +182,12,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1,Valid +183,15,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O,Valid +184,18,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3,Valid +185,18,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3,Valid +186,21,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1,Valid +187,18,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23,Valid +188,6,Cyano carbonyl compounds ,N#CC(=O),N#CC=O,Valid +189,5,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N,Valid +190,6,Benzyl ammoniums,cC[NX4+],cC[N+],Valid +191,8,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O,Valid +192,9,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N,Valid +193,7,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O,Valid +194,3,Singel acyclic N-N bonds,[#7]!@-N,N~N,Valid +195,11,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N,Valid +196,7,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O,Valid +197,2,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS,Valid +198,8,Phosphonates,[#6]P(=O)O[#6],COP(C)=O,Valid +199,16,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +200,14,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O,Valid +201,4,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS,Valid +202,13,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O,Valid +203,11,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F,Valid +204,4,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O,Valid +205,20,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1,Valid +206,15,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1,Valid +207,3,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC,Valid +208,4,Phosphocyanates,PC#N,N#CP,Valid +209,8,α-Hydroxy nitriles,N#CC[OH],N#CC[OH],Valid +210,6,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O,Valid +211,2,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO,Valid +212,11,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N,Valid +213,3,Nitroso compounds,[NX2]=O,N=O,Valid +214,19,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F,Valid +215,22,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +216,17,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1,Valid +217,1,Phosphorus derivatives,[P!v5],P,Valid +218,12,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C,Valid +219,22,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1,Valid +220,18,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1,Valid +221,17,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1,Valid +222,17,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1,Valid +223,7,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O,Valid +224,15,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O,Valid +225,14,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1,Valid +226,6,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC,Valid +227,16,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH],Valid +228,18,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1,Valid +229,20,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21,Valid +230,14,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH],Valid +231,17,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1,Valid +232,15,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21,Valid +233,6,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c,Valid +234,11,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N,Valid +235,6,Phosphorus cations,[#15+],[PH4+],Valid +236,10,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O,Valid +237,3,Double P=O bonds,[#15]=O,O=P,Valid +238,5,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH],Valid +239,7,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +240,3,Nitrosos,[NX2]=[OX1],N=O,Valid +241,10,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F,Valid +242,7,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S,Valid +243,5,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH],Valid +244,12,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH],Valid +245,12,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH],Valid +246,5,Phenols,c[OH1],c[OH],Valid +247,3,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC,Valid +248,3,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc,Valid +249,3,Diarylethers,c[OX2&!$([OX2r3])]c,cOc,Valid +250,6,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid +251,6,Primary aromatic amines,[NX3H2]c,c[NH2],Valid +252,6,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C,Valid +253,6,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C,Valid +254,6,Secondary aromatic amines,[NX3H1](c)c,c[NH]c,Valid +255,6,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C,Valid +256,5,Organolithium compounds,[Li][#6],[Li]C,Valid +257,5,Organomagnesium compounds,[Mg][#6],C[Mg],Valid +258,7,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O,Valid +259,10,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O,Valid +260,7,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O,Valid +261,11,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH],Valid +262,9,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC,Valid +263,10,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH],Valid +264,13,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC,Valid +265,12,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O,Valid +266,11,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O,Valid +267,8,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O,Valid +268,7,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O,Valid +269,6,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH],Valid +270,4,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC,Valid +271,7,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C,Valid +272,5,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH],Valid +273,5,Thiophenols,c[Sv2H1],c[SH],Valid +274,13,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH],Valid +275,13,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH],Valid +276,6,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C,Valid +277,10,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O,Valid +278,12,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH],Valid +279,6,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C,Valid +280,7,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C,Valid +281,7,Alkynyl alcohols,[CX2]#[CX2][OH1],C#C[OH],Valid +282,7,Alkynyl thiols,[CX2]#[CX2][SH1],C#C[SH],Valid +283,21,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O,NC(COP(O)(O)=O)C(O)=O,Valid +284,24,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O,CC(OP(O)(O)=O)C(N)C(O)=O,Valid +285,31,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,Valid +286,10,sulphonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +287,14,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S,O=C(S)C(F)(F)F,Valid +288,5,hydroxamate_warhead,C([N;H1]([O;D1]))=O,ONC=O,Valid +289,12,thiol_warhead,NC(C[S;D1])C(O)=O,NC(CS)C(O)=O,Valid +290,6,acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +291,25,pentafluorophenylester,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +292,10,acyl_imidazole,"[C;!$(C-N)](=O)n1[c;H1,$([#6]([*;!R]))]n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1ccnc1,Valid +293,16,ortho_hydroiminoquinone,c1c([N;D1])c([N;D1])c[cH1][cH1]1,Nc1c[cH][cH]cc1N,Valid +294,3,phosphorus_phosphorus_bond,P~P,P~P,Valid +295,10,acyl_pyrazole,"[C;!$(C-N)](=O)n1n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1cccn1,Valid +296,12,acyl_123_triazole,"[#7;R1]1=,:[#7;R1]-,:[#7;R1](-C(=O))-,:[#6]=,:[#6]1",O=CN1C=CN=N1,Valid +297,7,alpha_dicarbonyl,C(=O)!@C(=O),O=C~C=O,Valid +298,14,trifluoroacetate_ester,C(F)(F)(F)C(=O)O,OC(=O)C(F)(F)F,Valid +299,2,sulf_D2_nitrogen,[S;D2](-[N;!$(N(=C));!$(N(-S(=O)(=O)));!$(N(-C(=O)))]),NS,Valid +300,18,triflate,OS(=O)(=O)(C(F)(F)(F)),OS(=O)(=O)C(F)(F)F,Valid +301,15,rhodanine,C(=C)1SC(=S)NC(=O)1,C=C1SC(=S)NC1=O,Valid +302,5,NO_phosphonate,P(=O)ON,NOP=O,Valid +303,3,azo_filter3,[N;!R]-[N;!R]-[N;!R],NNN,Valid +304,30,disulfonyliminoquinone,S(=O)(=O)N=C1C=CC(=NS(=O)(=O))C=C1,O=S(=O)N=C1C=CC(=NS(=O)=O)C=C1,Valid +305,28,perchloro_cp,C1(Cl)(Cl)C(Cl)C(Cl)=C(Cl)C1(Cl),ClC1C(Cl)=C(Cl)C(Cl)C1(Cl)Cl,Valid +306,20,meldrums_acid_deriv,O=C1OC(C)(C)OC(C1)=O,CC1(C)OC(=O)CC(=O)O1,Valid +307,2,sulf_D2_oxygen_D2,[S;D2][O;D2],OS,Valid +308,3,azo_filter2,[N;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!r3;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!$(N-S(=O)(=O));!$(N-C=O)],NNN,Valid +309,2,hydrazine,[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))]-[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))],NN,Valid +310,10,isonitrile,[N+]#[C-],[C-]#[NH+],Valid +311,14,gte_3_COOH,C(=O)[O;D1].C(=O)[O;D1].C(=O)[O;D1],OC=O.OC=O.OC=O,Valid +312,3,phosphorus_sulfur_bond,P~S,P~S,Valid +313,9,polyene,C=[C;!R][C;!R]=[C;!R][C;!R]=[C;!R],C=CC=CC=C,Valid +314,4,azo_amino,[N]=[N;!R]-[N],N=NN,Valid +315,7,nitrone,[C;!R]=[N+][O;D1],C=[N+]O,Valid +316,1,sulfonium,[S+;X3;$(S-C);!$(S-[O;D1])],S,Valid +317,3,polysulfide,[S;D2]-[S;D2]-[S;D2],SSS,Valid +318,6,acrylate,[CH2]=[C;!$(C-N);!$(C-O)]C(=O),C=CC=O,Valid +319,15,four_nitriles,C#N.C#N.C#N.C#N,C#N.C#N.C#N.C#N,Valid +320,3,phosphorane,C=P,C=P,Valid +321,20,gte_7_aliphatic_OH,C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1],CO.CO.CO.CO.CO.CO.CO,Valid +322,9,gte_2_free_phos,P([O;D1])=O.P([O;D1])=O,OP=O.OP=O,Valid +323,22,benzidine_like,c([N;!+])1ccc(c2ccc([N;!+])cc2)cc1,Nc1ccc(c2ccc(N)cc2)cc1,Valid +324,9,hydrazothiourea,[N;!R]=NC(=S)N,NC(=S)N=N,Valid +325,4,nitrosamine,N-[N;X2](=O),NN=O,Valid +326,10,gte_10_carbon_sb_chain,[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R],CCCCCCCCCC,Valid +327,10,betalactam,C1(=O)~[#6]~[#6]N1,O=C1NC~C~1,Valid +328,3,peroxide,[#8]~[#8],O~O,Valid +329,18,paraquat_like,[#6]1[#6][#6]([#6]2[#6][#6][#7;+][#6][#6]2)[#6][#6][#7;+]1,C1CC(C2CCNCC2)CCN1,Valid +330,5,azo_aryl,c[N;!R;!+]=[N;!R;!+]-c,cN=Nc,Valid +331,2,disulfide_acyclic,[S;!R;X2]-[S;!R;X2],SS,Valid +332,5,gte_3_iodine,[#53].[#53].[#53],I.I.I,Valid +333,17,porphyrin,"[#6;r16,r17,r18]~[#6]1~[#6]~[#6]~[#6](~[#6])~[#7]1",C~C1N~C(~C)~C~C~1,Valid +334,7,thio_xanthate,[S;!R]-[C;!R](=[S;!R])(-[S;!R]),S=C(S)S,Valid +335,13,double_trouble_warhead,NC(C[S;D1])C([N;H1]([O;D1]))=O,NC(CS)C(=O)NO,Valid +336,13,Hzone_phenol_A,c1ccc(c(c1)[#8!H0])[#6]=[#7][#7],NN=Cc1ccccc1O,Valid +337,3,Azo_A,[N!R]=N,N=N,Valid +338,14,Mannich_A,N[CX4]c1c([OH1])cccc1,NCc1ccccc1[OH],Valid +339,15,Ene_rhod_A,N1C(=S)SC(=C)C1=O,C=C1SC(=S)NC1=O,Valid +340,18,Hzone_phenol_B,c1(ccc(cc1)C=N[#7])[OH1],NN=Cc1ccc([OH])cc1,Valid +341,20,Imine_one_isatin,[OX1]=C2C(=;!@N[#7])c3c(cccc3)N2,NN=C1C(=O)Nc2ccccc21,Valid +342,18,Anil_di_alk_B,c1c(ccc(c1)[#6]=[#6])[#7]([CX4])[CX4],CN(C)c1ccc(C=C)cc1,Valid +343,16,Catechol_A,c1ccc(c(c1)[OH1])[OH1],[OH]c1ccccc1[OH],Valid +344,21,Ene_five_one_A,c2ccc1C(=[OX1])C(=C)C(=[OX1])c1c2,C=C1C(=O)c2ccccc2C1=O,Valid +345,12,Ene_five_het_B,C1(=C)C(N=CS1)=O,C=C1SC=NC1=O,Valid +346,15,Ene_five_het_D,C1(=C)C(=[OX1])NNC1=[OX1],C=C1C(=O)NNC1=O,Valid +347,27,Ene_five_het_F,c1(ccccc1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)S2,O=C1C(=Cc2ccccc2)Sc2ccccc21,Valid +348,20,Ene_one_ester,[#6][#6](=[#8])[#6!H0]=[#6]([#7!H0][#6])[#6](=[#8])[#8][#6],CNC(=CC(C)=O)C(=O)OC,Valid +349,18,Ene_one_D,c([OH1])c-C(=[OX1])[C!H0]=C([#6])[#6],CC(C)=CC(=O)cc[OH],Valid +350,19,Ene_cyano_A,[#6](C#[#7])(C#[#7])=Cc1ccccc1,N#CC(=Cc1ccccc1)C#N,Valid +351,21,Hzone_pyrrol,n1(C)[cH1][cH1][cH1]c1C=NN,Cn1[cH][cH][cH]c1C=NN,Valid +352,45,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2,C=NNC(=O)c1[cH]c2[cH][cH][cH][cH]c2[cH]c1[OH],Valid +353,19,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1,O=C1CC(=O)c2ccccc21,Valid +354,22,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1],N#CC=C([NH2])C(C#N)C#N,Valid +355,20,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1,N#CC(C#N)=NNc1ccccc1,Valid +356,20,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9,C1C=CC2C1CNc1ccccc12,Valid +357,21,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7],Nc1c2ccccc2nc2ccccc12,Valid +358,13,Thiophene_hydroxy,"[#16]1-,:[#6]=,:[#6]-,:[#6](=,:[#6]1)[OH1]",[OH]C1=CSC=C1,Valid +359,25,Sulfonamide_B,c1c(ccc(c1)[NH]S(=[OX1])=[OX1])[OH1],O=S(=O)[NH]c1ccc([OH])cc1,Valid +360,7,Thio_ketone,"[#6]-,:[CX3](=[SX1])-,:[#6]",CC(C)=S,Valid +361,13,Rhod_sat_A,"[#7]1-,:[#6](=[#16])-,:[#16]-,:[#6X4]-,:[#6]1=[#8]",O=C1CSC(=S)N1,Valid +362,20,Imine_one_sixes,C1(C(=[OX1])NC(=[OX1])NC1(=[OX1]))=N,N=C1C(=O)NC(=O)NC1=O,Valid +363,22,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1,Valid +364,21,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1,Valid +365,21,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH],Valid +366,34,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +367,46,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH],Valid +368,31,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH],Valid +369,31,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1,Valid +370,51,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1,Valid +371,25,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH],Valid +372,36,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1,Valid +373,14,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1,Valid +374,27,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2,Valid +375,72,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1,Valid +376,39,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12,Valid +377,24,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC,Valid +378,27,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1,Valid +379,40,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1,Valid +380,32,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH],Valid +381,45,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12,Valid +382,38,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1,Valid +383,21,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2],Valid +384,39,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1,Valid +385,27,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12,Valid +386,31,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1,Valid +387,34,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12,Valid +388,52,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1,Valid +389,25,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1,Valid +390,30,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1,Valid +391,18,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1,Valid +392,46,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1,Valid +393,18,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1,Valid +394,22,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1,Valid +395,34,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2,Valid +396,18,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1,Valid +397,46,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +398,39,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1,Valid +399,32,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1,Valid +400,34,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12,Valid +401,17,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1,Valid +402,29,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O,Valid +403,21,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12,Valid +404,29,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21,Valid +405,48,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1,Valid +406,48,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1,Valid +407,22,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1,Valid +408,38,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc,Valid +409,34,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1,Valid +410,45,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1,Valid +411,19,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3,Valid +412,33,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21,Valid +413,22,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21,Valid +414,28,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12,Valid +415,18,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1,Valid +416,14,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1,Valid +417,20,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc,Valid +418,13,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1,Valid +419,26,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1,Valid +420,42,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1,Valid +421,18,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1,Valid +422,41,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21,Valid +423,48,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12,Valid +424,52,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21,Valid +425,10,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1,Valid +426,22,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1,Valid +427,16,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2,Valid +428,19,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc,Valid +429,44,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1,Valid +430,24,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21,Valid +431,26,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2,Valid +432,29,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21,Valid +433,30,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc,Valid +434,33,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21,Valid +435,15,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN,Valid +436,15,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S,Valid +437,12,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N,Valid +438,65,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1,Valid +439,25,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1,Valid +440,12,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S,Valid +441,23,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S,Valid +442,24,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1,Valid +443,47,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1,Valid +444,16,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O,Valid +445,17,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S,Valid +446,15,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1,Valid +447,41,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O,Valid +448,19,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1,Valid +449,31,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N,Valid +450,28,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21,Valid +451,21,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N,Valid +452,39,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2],Valid +453,48,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1,Valid +454,19,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N,Valid +455,27,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N,Valid +456,24,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc,Valid +457,16,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O,Valid +458,14,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O,Valid +459,19,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O,Valid +460,22,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12,Valid +461,23,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc,Valid +462,25,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1,Valid +463,15,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C,Valid +464,15,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1,Valid +465,18,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1,Valid +466,29,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O,Valid +467,33,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1,Valid +468,24,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1,Valid +469,28,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1,Valid +470,10,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1,Valid +471,22,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1,Valid +472,26,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1,Valid +473,25,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1,Valid +474,18,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S,Valid +475,18,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12,Valid +476,44,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1,Valid +477,52,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1,Valid +478,19,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2,Valid +479,22,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1,Valid +480,11,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1,Valid +481,22,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N,Valid +482,20,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12,Valid +483,27,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C,Valid +484,30,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N,Valid +485,28,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1,Valid +486,32,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH],Valid +487,23,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc,Valid +488,33,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12,Valid +489,35,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1,Valid +490,13,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1,Valid +491,20,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O,Valid +492,10,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH],Valid +493,27,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O,Valid +494,20,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21,Valid +495,20,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1,Valid +496,50,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21,Valid +497,42,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21,Valid +498,33,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1,Valid +499,13,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O,Valid +500,22,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O,Valid +501,21,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1,Valid +502,30,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O,Valid +503,11,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C,Valid +504,20,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1,Valid +505,20,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1,Valid +506,16,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21,Valid +507,11,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C,Valid +508,17,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O,Valid +509,15,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH],Valid +510,22,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S,Valid +511,24,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1,Valid +512,34,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1,Valid +513,32,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21,Valid +514,36,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O,Valid +515,24,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1,Valid +516,15,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1,Valid +517,29,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2],Valid +518,40,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1,Valid +519,26,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1,Valid +520,15,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc,Valid +521,25,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1,Valid +522,54,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1,Valid +523,34,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1,Valid +524,22,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc,Valid +525,12,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1,Valid +526,24,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1,Valid +527,24,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O,Valid +528,26,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1,Valid +529,18,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1,Valid +530,46,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1,Valid +531,26,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1,Valid +532,26,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3,Valid +533,25,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1,Valid +534,16,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N,Valid +535,28,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1,Valid +536,36,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O,Valid +537,38,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1,Valid +538,25,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1,Valid +539,38,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1,Valid +540,72,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2,Valid +541,56,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1,Valid +542,40,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1,Valid +543,20,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23,Valid +544,22,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2,Valid +545,35,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F,Valid +546,27,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2,Valid +547,35,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O,Valid +548,21,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1,Valid +549,38,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1,Valid +550,28,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1,Valid +551,32,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O,Valid +552,36,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1,Valid +553,29,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O,Valid +554,32,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O,Valid +555,61,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1,Valid +556,87,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH],Valid +557,27,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH],Valid +558,57,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1,Valid +559,59,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3],Valid +560,49,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1,Valid +561,49,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1,Valid +562,40,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH],Valid +563,23,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH],Valid +564,35,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1,Valid +565,39,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1,Valid +566,25,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1,Valid +567,81,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1,Valid +568,22,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1,Valid +569,31,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH],Valid +570,5,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1,Valid +571,5,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1,Valid +572,5,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1,Valid +573,6,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1,Valid +574,6,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1,Valid +575,6,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1,Valid +576,6,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1,Valid +577,5,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1,Valid +578,5,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1,Valid +579,5,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1,Valid +580,5,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1,Valid +581,6,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1,Valid +582,6,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1,Valid +583,6,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1,Valid +584,6,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1,Valid +585,5,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1,Valid +586,5,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1,Valid +587,5,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1,Valid +588,5,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1,Valid +589,5,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1,Valid +590,5,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1,Valid +591,5,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1,Valid +592,6,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1,Valid +593,6,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1,Valid +594,6,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1,Valid +595,6,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1,Valid +596,6,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1,Valid +597,6,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1,Valid +598,7,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1,Valid +599,7,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1,Valid +600,8,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1,Valid +601,7,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1,Valid +602,7,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1,Valid +603,6,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1,Valid +604,6,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1,Valid +605,6,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1,Valid +606,6,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1,Valid +607,6,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1,Valid +608,6,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1,Valid +609,7,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1,Valid +610,7,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1,Valid +611,7,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1,Valid +612,7,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1,Valid +613,7,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1,Valid +614,8,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1,Valid +615,8,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1,Valid +616,8,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1,Valid +617,8,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1,Valid +618,8,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1,Valid +619,8,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1,Valid +620,8,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1,Valid +621,7,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1,Valid +622,7,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1,Valid +623,7,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1,Valid +624,13,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1,Valid +625,13,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1,Valid +626,13,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1,Valid +627,7,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1,Valid +628,7,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1,Valid +629,7,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1,Valid +630,7,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1,Valid +631,7,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1,Valid +632,7,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1,Valid +633,8,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1,Valid +634,8,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1,Valid +635,8,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1,Valid +636,8,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1,Valid +637,8,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1,Valid +638,8,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1,Valid +639,8,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1,Valid +640,8,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1,Valid +641,8,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1,Valid +642,7,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1,Valid +643,7,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1,Valid +644,7,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1,Valid +645,7,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1,Valid +646,7,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1,Valid +647,7,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1,Valid +648,7,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1,Valid +649,7,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1,Valid +650,7,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1,Valid +651,7,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1,Valid +652,7,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1,Valid +653,7,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1,Valid +654,8,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1,Valid +655,8,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1,Valid +656,7,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1,Valid +657,7,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1,Valid +658,7,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1,Valid +659,7,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1,Valid +660,7,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1,Valid +661,7,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1,Valid +662,7,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1,Valid +663,7,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1,Valid +664,7,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1,Valid +665,7,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1,Valid +666,7,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1,Valid +667,7,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1,Valid +668,7,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1,Valid +669,7,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1,Valid +670,7,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1,Valid +671,7,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1,Valid +672,7,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1,Valid +673,7,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1,Valid +674,8,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1,Valid +675,8,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1,Valid +676,8,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1,Valid +677,9,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1,Valid +678,9,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1,Valid +679,8,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1,Valid +680,8,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1,Valid +681,8,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1,Valid +682,8,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1,Valid +683,8,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1,Valid +684,8,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1,Valid +685,8,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1,Valid +686,8,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1,Valid +687,8,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1,Valid +688,5,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C,Valid +689,5,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF,Valid +690,6,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl,Valid +691,6,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr,Valid +692,5,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI,Valid +693,4,Vinyl fluorides,F[CX3]=[CX3],C=CF,Valid +694,5,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl,Valid +695,5,Vinyl bromides,Br[CX3]=[CX3],C=CBr,Valid +696,4,Vinyl iodides,I[CX3]=[CX3],C=CI,Valid +697,4,Alkynyl fluorides,F[CX2]#[CX2],C#CF,Valid +698,5,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl,Valid +699,4,Alkynyl iodides,I[CX2]#[CX2],C#CI,Valid +700,5,Alkynyl bromides,Br[CX2]#[CX2],C#CBr,Valid +701,3,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC,Valid +702,3,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc,Valid +703,3,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc,Valid +704,10,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH],Valid +705,10,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH],Valid +706,5,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C,Valid +707,5,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C,Valid +708,7,Aldehyde,[CX3H1](=O)[#6],C[CH]=O,Valid +709,3,Formaldehyde,[CX3H2](=O),C=O,Valid +710,7,Ketone,[C][C](=O)[C],CC(C)=O,Valid +711,3,Nitrile,[C]#[N],C#N,Valid +712,27,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1,Valid +713,42,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1,Valid +714,19,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21,Valid +715,17,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21,Valid +716,14,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1,Valid +717,10,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1,Valid +718,14,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n,Valid +719,21,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12,Valid +720,21,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1,Valid +721,16,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1,Valid +722,10,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn,Valid +723,17,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1,Valid +724,18,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1,Valid +725,18,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12,Valid +726,18,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12,Valid +727,23,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12,Valid +728,26,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1,Valid +729,18,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1,Valid +730,18,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1,Valid +731,26,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1,Valid +732,18,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1,Valid +733,25,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1,Valid +734,21,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1,Valid +735,21,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12,Valid +736,18,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12,Valid +737,16,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH],Valid +738,16,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S,Valid +739,16,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH],Valid +740,16,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH],Valid +741,16,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S,Valid +742,22,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C,Valid +743,16,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH],Valid +744,22,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C,Valid +745,23,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S,Valid +746,19,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S,Valid +747,21,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH],Valid +748,22,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH],Valid +749,14,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH],Valid +750,11,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH],Valid +751,19,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1,Valid +752,16,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1,Valid +753,24,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1,Valid +754,21,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1,Valid +755,20,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1,Valid +756,11,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1,Valid +757,27,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21,Valid +758,30,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1,Valid +759,22,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12,Valid +760,16,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH],Valid +761,18,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH],Valid +762,22,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH],Valid +763,22,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH],Valid +764,28,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH],Valid +765,27,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH],Valid +766,25,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1,Valid +767,25,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1,Valid +768,29,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1,Valid +769,25,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1,Valid +770,13,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O,Valid +771,4,Pt,[Pt],[Pt],Valid +772,7,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +773,9,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O,Valid +774,34,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +775,28,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1,Valid +776,51,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1,Valid +777,46,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +778,33,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1,Valid +779,36,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21,Valid +780,11,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1,Valid +781,32,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12,Valid +782,35,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1,Valid +783,18,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH],Valid +784,21,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1,Valid +785,32,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1,Valid +786,19,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12,Valid +787,1,Radical,[#16;X3v3+0],S,Valid +788,4,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +789,9,6 - Methanol,[CX4H3][OX2H1],[CH3][OH],Valid +790,1,7 - Water,[OX2H2],O,Valid +791,7,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O,Valid +792,8,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +793,13,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +794,5,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S,Valid +795,15,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +796,18,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +797,1,32 - Iodo compounds,[I],I,Valid +798,2,33 - Bromo compounds,[Br!$([Br][cR])],Br,Valid +799,15,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +800,9,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +801,5,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl,Valid +802,8,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +803,26,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +804,27,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +805,7,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +806,6,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C,Valid +807,9,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH],Valid +808,3,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C,Valid +809,6,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C,Valid +810,3,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C,Valid +811,5,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c,Valid +812,4,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +813,9,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH],Valid +814,1,17 - H2O (7 - Water),[OX2H2],O,Valid +815,11,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O,Valid +816,11,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O,Valid +817,7,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O,Valid +818,12,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O,Valid +819,12,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O,Valid +820,8,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +821,7,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3],Valid +822,7,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2],Valid +823,10,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2],Valid +824,10,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2],Valid +825,9,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2],Valid +826,10,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3],Valid +827,10,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2],Valid +828,9,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH],Valid +829,10,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3],Valid +830,10,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2],Valid +831,23,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1,Valid +832,8,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N,Valid +833,8,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N,Valid +834,7,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH],Valid +835,10,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH],Valid +836,7,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl,Valid +837,9,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl,Valid +838,12,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl,Valid +839,13,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +840,5,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S,Valid +841,9,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH],Valid +842,9,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH],Valid +843,15,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +844,18,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +845,1,64 - I (32 - Iodo compounds),[I],I,Valid +846,2,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br,Valid +847,3,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C,Valid +848,3,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C,Valid +849,15,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +850,9,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +851,5,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl,Valid +852,19,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O,Valid +853,19,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O,Valid +854,8,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +855,6,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3],Valid +856,7,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2],Valid +857,6,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH],Valid +858,5,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si],Valid +859,26,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +860,12,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl,Valid +861,11,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl,Valid +862,10,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl,Valid +863,10,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl,Valid +864,11,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl,Valid +865,8,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O,Valid +866,12,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O,Valid +867,12,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O,Valid +868,16,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O,Valid +869,16,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O,Valid +870,16,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O,Valid +871,15,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH],Valid +872,27,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +873,21,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1,Valid +874,19,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O,Valid +875,18,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O,Valid +876,13,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1,Valid +877,12,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1,Valid +878,9,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1,Valid +879,11,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1,Valid +880,8,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1,Valid +881,5,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1,Valid +882,7,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +883,10,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O,Valid +884,11,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C,Valid +885,35,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1,Valid +886,11,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1,Valid +887,18,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1,Valid +888,14,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O,Valid +889,7,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O,Valid +890,2,R7 - Peroxides,OO,OO,Valid +891,25,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +892,21,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1,Valid +893,7,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O,Valid +894,18,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +895,7,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S,Valid +896,10,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +897,12,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-],Valid +898,5,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O,Valid +899,3,R19 - Phosphoranes,C=P,C=P,Valid +900,8,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +901,3,R21 - Nitroso,[N&D2](=O),N=O,Valid +902,5,R23 - Carbodiumide,N=C=N,N=C=N,Valid +903,10,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +904,13,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +905,8,R26 - Cyanohydrins,N#CC[OH],N#CC[OH],Valid +906,6,R27 - Acyl cyanides,N#CC(=O),N#CC=O,Valid +907,10,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O,Valid +908,16,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +909,6,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N,Valid +910,7,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +911,7,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC,Valid +912,7,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +913,2,I4 - Disulphides,SS,SS,Valid +914,4,I5 - Thiols,[SH],[SH],Valid +915,17,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +916,18,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +917,9,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +918,4,I10 - Thiocyanate,SC#N,N#CS,Valid +919,6,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+],Valid +920,9,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N,Valid +921,8,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1,Valid +922,19,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +923,8,I16 - Betalactams,N1CCC1=O,O=C1CCN1,Valid +924,16,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1,Valid +925,12,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +926,25,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +927,15,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +928,14,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +929,17,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +930,55,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1,Valid +931,14,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +932,13,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1,Valid +933,13,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1,Valid +934,20,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1,Valid +935,17,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O,Valid +936,12,A8,[nH1]1ncoc1=O,O=c1[nH]nco1,Valid +937,13,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1,Valid +938,15,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1,Valid +939,16,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1,Valid +940,13,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1,Valid +941,12,A13,[nH1]1occc1=O,O=c1cco[nH]1,Valid +942,11,A14,[OH1]c1oncc1,[OH]c1ccno1,Valid +943,12,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1,Valid +944,7,A16 - tetrazole,[nH1]nnn,nnn[nH],Valid +945,7,A17,[nH1](n)nn,nn[nH]n,Valid +946,16,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1,Valid +947,16,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1,Valid +948,18,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1,Valid +949,18,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1,Valid +950,16,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1,Valid +951,16,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1,Valid +952,16,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1,Valid +953,26,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21,Valid +954,26,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21,Valid +955,22,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21,Valid +956,16,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH],Valid +957,13,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1,Valid +958,8,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH],Valid +959,21,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F,Valid +960,12,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O,Valid +961,6,B1 - primary amine,[NH2][CX4],C[NH2],Valid +962,6,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C,Valid +963,6,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C,Valid +964,8,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1,Valid +965,7,E4EXC,C(=O)[OH1],O=C[OH],Valid +966,7,E5EXC,C(=O)[SH1],O=C[SH],Valid +967,5,E9EXC,P[OH1],[OH]P,Valid +968,9,E11,c(=O)(~c)~c,c~c(~c)=O,Valid +969,7,E13 - imides,C(=O)-N-C=O,O=CNC=O,Valid +970,6,N1 - pimary amines,[NX3H2][CX4],C[NH2],Valid +971,6,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C,Valid +972,7,N7EXC,[OH1]C=C,C=C[OH],Valid +973,4,Acyclic C=C-O,C=[C!r]O,C=CO,Valid +974,6,Acyl cyanide,N#CC(=O),N#CC=O,Valid +975,9,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O,Valid +976,13,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1,Valid +977,33,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1,Valid +978,11,Azido group,N=[N+]=[N-],[N-]=[N+]=N,Valid +979,3,Azo group,N=N,N=N,Valid +980,38,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1,Valid +981,14,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +982,6,Conjugated nitrile group,C=[C!r]C#N,C=CC#N,Valid +983,16,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1,Valid +984,9,Cyanamide,N[CH2]C#N,N[CH2]C#N,Valid +985,8,Cyanohydrins,N#CC[OH],N#CC[OH],Valid +986,9,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1,Valid +987,9,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1,Valid +988,10,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1,Valid +989,10,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1,Valid +990,3,Diazo group,[N!R]=[N!R],N=N,Valid +991,2,Disulphide,SS,SS,Valid +992,2,Enamine,[CX3R0][NX3R0],CN,Valid +993,7,Ester of HOBT,C(=O)Onnn,nnnOC=O,Valid +994,8,Four member lactones,C1(=O)OCC1,O=C1CCO1,Valid +995,13,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1,Valid +996,8,Hydroxamic acid,C(=O)N[OH],O=CN[OH],Valid +997,3,Imine,C=[N!R],C=N,Valid +998,5,Ketene,C=C=O,C=C=O,Valid +999,10,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1,Valid +1000,11,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O,Valid +1001,14,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1,Valid +1002,5,N-hydroxylpyridine,n[OH],n[OH],Valid +1003,4,N-nitroso,[#7]-N=O,NN=O,Valid +1004,10,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F,Valid +1005,2,Peroxide,OO,OO,Valid +1006,15,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1,Valid +1007,15,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1,Valid +1008,1,Phosphor,P,P,Valid +1009,6,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C,Valid +1010,25,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1011,21,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1,Valid +1012,10,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1013,2,Sulfur oxygen single bond,[SX2]O,OS,Valid +1014,14,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-],Valid +1015,2,Sulphur nitrogen single bond,[SX2H0][N],NS,Valid +1016,15,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1,Valid +1017,15,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1,Valid +1018,5,Thiol (1),[S-],[SH-],Valid +1019,4,Thiol (2),[SH],[SH],Valid +1020,18,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +1021,3,Triple bond,C#C,C#C,Valid +1022,5,Deuterium,[2H],[2HH],Valid +1023,7,C13,[13#6],[13CH4],Valid +1024,10,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1,Valid +1025,23,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O,Valid +1026,2,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN,Valid +1027,3,Acyclic N-C-N,N-!@[CX4]-!@N,NCN,Valid +1028,6,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O,Valid +1029,27,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O,Valid +1030,20,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1,Valid +1031,7,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O,Valid +1032,9,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N,Valid +1033,7,26,N-C(=S)-N,NC(N)=S,Valid +1034,4,Thio cyanates,S-C#N,N#CS,Valid +1035,11,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O,Valid +1036,12,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2],Valid +1037,30,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2],Valid +1038,3,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N,Valid +1039,2,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO,Valid +1040,2,42,S-S,SS,Valid +1041,3,43,O~O,O~O,Valid +1042,18,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3,Valid +1043,7,Too many cyano groups (>1),C#N.C#N,C#N.C#N,Valid +1044,15,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH],Valid +1045,12,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O,Valid +1046,4,Chlorates,Cl~O,O~Cl,Valid +1047,5,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O,Valid +1048,6,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C,Valid +1049,2,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN,Valid +1050,8,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH],Valid +1051,14,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O,Valid +1052,50,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3],Valid +1053,2,Filter35_PP_bond,P-P,PP,Valid +1054,3,Filter36_SS_double_bond,S=S,S=S,Valid +1055,8,Filter37_silicate,[Si]~O,O~[SiH4],Valid +1056,6,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O,Valid +1057,6,Filter51_PN3,N[PX3](N)N,NP(N)N,Valid +1058,16,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +1059,2,Filter56_SS_bond,S-S,SS,Valid +1060,15,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1,Valid +1061,15,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1,Valid +1062,3,Filter59_phoshorous_ylide,C=P,C=P,Valid +1063,3,Filter60_Acyclic_N-S,N!@[SX2],N~S,Valid +1064,24,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F,Valid +1065,14,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH],Valid +1066,7,Filter73_thio_ketone,CC(=S)C,CC(C)=S,Valid +1067,7,Filter76_S_ester,CC(=S)O,CC(O)=S,Valid +1068,20,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1,Valid +1069,4,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N,Valid +1070,3,Filter90_N_double_bond_S,N=!@S,N=S,Valid +1071,12,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O,Valid +1072,7,Anhydride,C(=O)OC(=O),O=COC=O,Valid +1073,26,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1,Valid +1074,7,HOBT ester,C(=O)Onnn,nnnOC=O,Valid +1075,12,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-],Valid +1076,6,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N,Valid +1077,8,Cyanohydrin,N#CC[OH],N#CC[OH],Valid +1078,8,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +1079,13,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +1080,6,Benzylic quaternary nitrogen,cC[N+],cC[N+],Valid +1081,3,Phosphorane,C=P,C=P,Valid +1082,7,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S,Valid +1083,16,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +1084,4,Thiol,[SH],[SH],Valid +1085,20,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1,Valid +1086,18,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +1087,17,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1088,18,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1089,7,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1090,9,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +1091,13,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH],Valid +1092,8,Ester,[#6]-C(=O)O-[#6],COC(C)=O,Valid +1093,3,Imine 3,C=[NH],C=N,Valid +1094,7,Thioketone,CC(=S)C,CC(C)=S,Valid +1095,8,Thionoester,COC(=S)C,COC(C)=S,Valid +1096,7,Thioamide,CC(=S)N,CC(N)=S,Valid +1097,6,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC,Valid +1098,10,Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +1099,4,Thiocyanate,SC#N,N#CS,Valid +1100,21,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1,Valid +1101,6,Dye 2,OCccCO,OCccCO,Valid +1102,2,Disulfide,SS,SS,Valid +1103,11,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N,Valid +1104,6,Oxalyl,O=C-&!@C=O,O=CC=O,Valid +1105,15,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-],Valid +1106,19,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1107,10,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O,Valid +1108,18,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12,Valid +1109,26,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21,Valid +1110,28,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O,Valid +1111,8,Propiolactone,C1(=O)OCC1,O=C1CCO1,Valid +1112,8,b-Lactam,N1CCC1=O,O=C1CCN1,Valid +1113,14,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +1114,25,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1115,17,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +1116,14,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +1117,57,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1,Valid +1118,15,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +1119,28,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1,Valid +1120,17,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1121,18,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1122,7,Acid_anhydrides,C(=O)OC(=O),O=COC=O,Valid +1123,20,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1,Valid +1124,6,Acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +1125,19,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F,Valid +1126,12,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C,Valid +1127,28,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O,Valid +1128,4,Aminonitrile,NC#N,NC#N,Valid +1129,13,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-],Valid +1130,7,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1131,21,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1,Valid +1132,14,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +1133,14,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1,Valid +1134,17,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1,Valid +1135,20,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1,Valid +1136,7,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +1137,19,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1138,6,Diacetylene,C#CC#C,C#CC#C,Valid +1139,11,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-],Valid +1140,7,Diazonium_salt,[N+]#N,N#[NH+],Valid +1141,15,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O,Valid +1142,7,Dithiocarbamate,NC(=S)S,NC(S)=S,Valid +1143,10,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1,Valid +1144,10,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1,Valid +1145,3,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS,Valid +1146,6,Enyne,C=!@CC#C,C#CC=C,Valid +1147,7,Ester_of_HOBT,C(=O)Onnn,nnnOC=O,Valid +1148,30,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2,Valid +1149,8,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF,Valid +1150,10,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F,Valid +1151,8,Four_member_lactones,C1(=O)OCC1,O=C1CCO1,Valid +1152,3,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN,Valid +1153,7,Geminal_dinitriles,N#CCC#N,N#CCC#N,Valid +1154,14,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1,Valid +1155,7,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S,Valid +1156,4,Nitrosamine,N-[N;X2](=O),NN=O,Valid +1157,8,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-],Valid +1158,3,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN,Valid +1159,9,Orthoester,C(O)(O)[OH],OC(O)[OH],Valid +1160,20,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH],Valid +1161,13,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1,Valid +1162,3,PCP,PCP,PCP,Valid +1163,25,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +1164,26,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1165,13,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1,Valid +1166,12,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O,Valid +1167,10,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +1168,12,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +1169,11,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc,Valid +1170,8,Polyines,CC#CC#CC,CC#CC#CC,Valid +1171,20,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1,Valid +1172,22,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12,Valid +1173,26,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1174,11,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1,Valid +1175,3,S=N (not_ring),[S;R0]=[N;R0],N=S,Valid +1176,9,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O,Valid +1177,10,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1178,3,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S,Valid +1179,9,Tetraazinane,C1NNC=NN1,C1NNC=NN1,Valid +1180,14,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S,Valid +1181,15,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1,Valid +1182,29,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1,Valid +1183,32,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1,Valid +1184,17,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O,Valid +1185,11,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O,Valid +1186,14,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1,Valid +1187,3,Thiocarbonyl_group,C=S,C=S,Valid +1188,3,Enamine_like,C=[NH],C=N,Valid +1189,14,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F,Valid +1190,4,Triple_bond,[#6]C#[CH],CC#C,Valid +1191,15,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O,Valid +1192,12,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1,Valid +1193,17,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1,Valid +1194,8,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1,Valid +1195,9,Thiazolidinone,O=C1CSCN1,O=C1CSCN1,Valid +1196,14,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1,Valid +1197,12,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1,Valid +1198,15,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1,Valid +1199,3,Ethene,C=[CH2],C=C,Valid +1200,7,Cyclobutene,C1CC=C1,C1CC=C1,Valid +1201,1,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C,Valid +1202,17,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-],Valid +1203,21,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-],Valid +1204,4,Sulphur atom (1),[SX2H1],[SH],Valid +1205,1,Sulphur atom (6),[sX2r5],s,Valid +1206,1,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C,Valid +1207,1,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C,Valid +1208,1,Nitrogen atoms (7),[nr5H0],n,Valid +1209,27,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21,Valid +1210,16,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C,Valid +1211,25,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1,Valid +1212,24,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1,Valid +1213,31,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1,Valid +1214,25,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1,Valid +1215,24,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1,Valid +1216,27,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1,Valid +1217,27,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1,Valid +1218,20,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1,Valid +1219,19,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1,Valid +1220,19,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1,Valid +1221,23,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1,Valid +1222,22,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2,Valid +1223,22,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC,Valid +1224,21,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1,Valid +1225,16,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1,Valid +1226,27,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1227,32,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1228,34,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1,Valid +1229,20,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1,Valid +1230,20,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1,Valid +1231,16,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1,Valid +1232,22,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1,Valid +1233,22,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12,Valid +1234,21,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1,Valid +1235,14,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1,Valid +1236,17,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1,Valid +1237,17,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1,Valid +1238,32,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1,Valid +1239,20,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1,Valid +1240,12,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2,Valid +1241,11,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2,Valid +1242,19,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1,Valid +1243,15,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2,Valid +1244,6,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid diff --git a/Pre-Trained LSTM/FSR/vocab.csv b/Pre-Trained LSTM/FSR/vocab.csv new file mode 100644 index 0000000000000000000000000000000000000000..a8d112ae53e12daec50e4a32374afc22776e5794 --- /dev/null +++ b/Pre-Trained LSTM/FSR/vocab.csv @@ -0,0 +1,2787 @@ +,Functional grp name,SMARTS,Smiles +0,Acid halides,"[F,Cl,Br][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +1,Acid azides,"[CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C=O +2,Sulphonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[Cl,Br]",*S(C)(=O)=O +3,Sulphonyl azides,"[Sv6X4](=[OX1])(=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",*S(=O)=O +4,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +5,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O +6,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1 +7,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O +8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1 +9,Thioesters,[CX3](=[SX1])[SX2],SC=S +10,Haloalkanes,"[CX4][Cl,Br,I]",*C +11,Dialkylsulfates/ sulfonates,"[$([#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6]),$([#6][Sv6X4](=[OX1])(=[OX1])[OX2][#6])]",* +12,N-Trihalomethyl imides,"[CX3](=[OX1])[NX3]([CX4]([Cl,Br,I])([Cl,Br,I])[Cl,Br,I])[CX3](=[OX1])",*C(*)(*)N(C=O)C=O +13,Quinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]",* +14,Hydroquinones and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1][cR1][cR1]([OX2][#1,CX4])[cR1][cR1]1",*Oc1ccc(O*)cc1 +15,Catechols and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1]([OX2][#1,CX4])[cR1][cR1][cR1][cR1]1",*Oc1ccccc1O* +16,"α, β-Unsaturated aldehydes, amides, esters and ketones","[$([CX3]([#6,$([NX3]([CX3]=[OX1])([#6])[#6]),$([OX2]([CX3]=[OX1])[#6]);!$([OH][CX3]=[OX1]);!$([O-][CX3]=[OX1])])(=[OX1])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX3H1](=[OX1])[CX3]([#6,#1])=[CX3])]",* +17,"Precursors of α, β-unsaturated aldehydes, amides, esters and ketones (1)","[$([CX4]([OX2])([OX2])([#6,#7,#8])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX4H1]([OX2])([OX2])[CX3]([#6,#1])=[CX3])]",* +18,"1,3-Diketones","[CX4,a!r0][CX3](=[OX1])[CH2][CX3](=[OX1])[CX4,a!r0]",*C(=O)[CH2]C(*)=O +19,Aldehydes,"[CX3]([H])(=[OX1])[#1,CX4,a!r0]",*C([H])=O +20,Ketones,"[CX4,a!r0][CX3](=[OX1])[CX4,a!r0]",*C(*)=O +21,Formaldehyde donors,"[$([NX3][CH2][NX3]),$([NX3][CH2][OX2]),$([CX4]([F,Cl,Br,I])([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])[CH2][OH1])]",* +22,Precursors of aldehydes and ketones,"[CX4]([OX2])([OX2])([CX4,a!r0])[CX4,a!r0]",*C(*)(O)O +23,Enol precursor of aldehydes and ketones,"[CX3]=[CX3]([#6,#1])[OX2]",*C(=C)O +24,Aromatic primary and secondary amines,"[a!r0][$([NX3H2]),$([NX3H1][CX4,a!r0])]",** +25,N-Haloimides,"[CX3](=[OX1])[NX3]([Cl,Br])[CX3](=[OX1])",*N(C=O)C=O +26,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl +27,Disullides,"[CX4,a!r0][SX2][SX2][CX4,a!r0]",*SS* +28,Phenyl carbonates,"c1ccccc1[OX2][CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)Oc1ccccc1 +29,Epoxides,[CX4]1[CX4][OX2]1,C1CO1 +30,1.2-Dicarbonyls,"[CX4,a!r0][CX3](=[OX1])[CX3](=[OX1])[#1,CX4,a!r0]",*C(=O)C(*)=O +31,Thiazolones,"[$([SX2]1[CX3]([CX4,a!r0])=[CX3]([CX4,a!r0])[CX3](=[OX1])[NX3]1([CX4,a!r0])),$([sX2]1[cX3]([CX4,a!r0])[cX3]([CX4,a!r0])[cX3](=[OX1])[nX3]1([CX4,a!r0]))]",* +32,"1, 2-Diamines","[CX4,a!r0][NX3H1][CX4][CX4][NX3H1][CX4,a!r0]",*[NH]CC[NH]* +33,Quaternary ammonium cation,"[NX4+]([CX4,a!r0])([CX4,a!r0])([CX4,a!r0])[CX4,a!r0]",*[N+](*)(*)* +34,Activated N-heterocycle halides,"[$(n1c([F,Cl])ncnc1),$(n1c([F,Cl])ccnc1),$(n1c([F,Cl])nccc1)]",* +35,Aromatic sulphuric acids and salts,"[a!r0][Sv4X3](=[OX1])[$([OH]),$([O-])]",*S(*)=O +36,Iso(thio)cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +37,Acid imides,"[NX3]1([#1,#6])[CX3](=[OX1])[CX3]([!R])=[CX3]([!R])[CX3]1(=[OX1])",*C1=C(*)C(=O)N(*)C1=O +38,Activated N-heterocycles,"[$(n1c([F,Cl,$([CX2]#[NX1])])nccc1),$(n1cnccc1([F,Cl,$([CX2]#[NX1])])),$(n1cncnc1([F,Cl,$([CX2]#[NX1])]))]",* +39,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +40,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC +41,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1 +42,Aldehydes and precursors,"[$([#1,#6;!$(C=C);!$(C#C)][CX3]([H])(=[OX1])),$([CX4;H1]([OX2])[OX2])]",* +43,"α, β-Unsaturated carbonyls","[CX3]=[CX3][CX3](=[OX1])[$([OX2]([CX3]=[OX1])[!#1]),$([#1][CX3]=[OX1]),$([NX3H2]([CX3]=[OX1])),$([NX3]([CX3]=[OX1])),$([CX4][CX3]=[OX1])]",*C(=O)C=C +44,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +45,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH] +46,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1 +47,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1 +48,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1 +49,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH] +50,Thiols,[#16X2H1],[SH] +51,Disulfides,*[#16X2][#16X2]*,*SS* +52,Diaryl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[a!r0],*C(=O)OOC(*)=O +53,Arylacyl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[A],*C(=O)OOC(*)=O +54,Haloamides,"[#6][CX3](=[OX1])[NX3]([F,Cl,Br,I])[#6]",*N(C)C(C)=O +55,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH] +56,"1,2-Dihydroxy aromatic compounds",[OH1]aa[OH1],[OH]*:*[OH] +57,"1,4-Dihydroxy aromatic compounds",[OH1]aaaa[OH1],[OH]*:*:*:*[OH] +58,2 or 4-Hydroxysubstituted alkylphenyl ether,"[$(c1c([OX2][CX4])c([OH1])ccc1),$(c1c([OX2][CX4])ccc([OH1])c1)]",* +59,Aromatic amines,"[a!r0][$([NX3H2]),$([NX3H1][#6])]",** +60,Aromatic amines precursors,"[$([a!r0][NH1][CX3](=[OX1])),$(c1c([NX2]=[NX2][a!r0])ccc([$([NX3]([CX4])([CX4])),$([NX3H1][CX4]),$([NH2]),$([OH1])])c1)]",* +61,Alkyl or aryl sylfonyl halides,"[CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +62,Sulfonamides,"c1c([Sv6X4](=[OX1])(=[OX1])[NX3H1][$([#1]),$([CX4]),$([a!r0])])ccc([NX3H2])c1",*[NH]S(=O)(=O)c1ccc([NH2])cc1 +63,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S +64,Hydrazines,"[#6&!$([CX3]=[OX1,SX1,NX2])][NX3H1][NX3H2,$([NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])])]",*[NH]C +65,Aromatic nitro (general),"[a!r0][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",** +66,Aromatic amine (general),[a!r0][NX3H2],*[NH2] +67,Three-membered heterocycles (general),"[NX3H1,SX2,OX2]1[CX4][CX4]1",*1CC1 +68,Nitroso (general),[NX2]=[OX1],N=O +69,Unsubstituted heteroatom-bonded heteroatom (general),"[$([NX3H2]-[#7]),$([NX3H2]-[#8]),$([OX2H1]-[#7]),$([OX2H1]-[#8])]",* +70,Azo-type (general),[NX2]=[NX2],N=N +71,Aliphatic halide (general),"[CX4][Cl,Br,I]",*C +72,Polycyclic aromatic system (general),"[$([aR3]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))])]",* +73,Aromatic nitroso (specific),[a!r0][NX2]=[OX1],*N=O +74,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O +75,Nitrosamine (specific),"[OX1]=[NX2][NX3]([#6,#1])[#6,#1]",*N(*)N=O +76,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1 +77,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1 +78,Azide (specific),"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +79,Diazo (specific),"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +80,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N +81,Aromatic hydroxylamine (specific),[a!r0][NX3H1][OH1],*[NH][OH] +82,Aliphatic halide (specific),"[Cl,Br,I][$([CX4]);!$([CX3](=[OX1,SX1,NX2]));!$([CH2][CH2][SX2,NX3])]",** +83,Carboxylic acid halide (specific),"[Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +84,Nitrogen and sulphur mustard (specific),"[Cl,Br,I][CH2][CH2][SX2,NX3]",*[CH2][CH2]* +85,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1 +86,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1 +87,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O +88,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O +89,Aliphatic N-nitro (additional),"[NX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1][O-]))]",*N +90,Diazonium (additional),"[$([a!r0][NX2+]#[NX1]),$([a!r0][NX2]#[NX1])]",* +91,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +92,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH] +93,1-Aryl-2-monoalkyl hydrazine (additional),[a!r0][NX3H1]-[NX3H1][CX4],*[NH][NH]C +94,Aromatic methylamine (additional),[a!r0][NX3;H1][CH3],*N[CH3] +95,Aromatic hydroxylamine ester (additional),[a!r0][NH][OX2][CX3](=[OX1]),*[NH]OC=O +96,Polycyclic planar system (additional),[*R1]1[*R2]2=[*R1][*R1]=[*R1][*R1]=[*R2]2[*R1][*R2]3=[*R1][*R1]=[*R1][*R1]=[*R2]13,*1*2=**=**=*2**2=**=**=*12 +97,Acyl halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +98,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +99,Monohaloalkene,"[CX3]([CX4,#1])([F,Cl,Br,I])=[CX3]([CX4,#1])[!F!Cl!Br!I]",*C(*)=C(*)* +100,S or N mustard,"[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +101,Propiolactones or propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +102,Epoxides and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +103,Aliphatic halogens,"[CX4;!H0][Br,Cl,I]",*C +104,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O +105,Simple aldehyde,"[CX3]([H])(=[OX1])[#1,#6&!$([CX3]=[CX3])]",*C([H])=O +106,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN +107,Aliphatic azo and azoxy,"[$([C,#1][NX2]=[NX2][C,#1]),$([CX3]=[NX2+]=N),$([CX3]=[NX2+]=[NX1-]),$([CX3-][NX2+]#[NX1]),$([CX3][NX2]#[NX1]),$(C[NX2]=N(=O)[*]),$(C[NX2]=[N+]([O-])[*])]",* +108,Isocyanate and isothiocyanate groups,"[NX2]=[CX2]=[OX1,Sv2X1]",*=C=N +109,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +110,Thiocarbonyl,"[$([NX3][CX3](=[Sv2X1])[NX3]),$([CX3;!$(C[OH]);!$(C[SH]);!$(C[O-]);!$(C[S-]);!$(CO[#6])](=[Sv2X1])[NX3])]",* +111,Heterocyclic polycyclic aromatic hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +112,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O +113,Azide and triazene groups,"[$([NX2!R]=[NX2!R][NX3!R]),$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",* +114,Aliphatic N-nitro group,"[NX3]([#1,C])([#1,C])[$([NX3+](=[OX1])[O-]),$([NX3](=O)=O)]",*N(*)* +115,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC +116,Aromatic nitroso group,[a!r0][NX2]=[OX1],*N=O +117,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +118,Coumarins and furocoumarins,"[$(c1cccc2c1oc(=O)cc2),$(C1=CC(=O)OC2=CC=CC=C12),$(C1=CC(=O)Oc2ccccc12)]",* +119,Halogenated benzene,"c1ccccc1[$([Br,Cl,F,I]);!$([Br,Cl,F,I]aa[Br,Cl,F,I]);!$([Br,Cl,F,I]aaa[Br,Cl,F,I]);!$([Br,Cl,F,I]aa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aaa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aa([OH])a([OH])aa[OH])]",*c1ccccc1 +120,Halogenated PAH,"[Br,Cl,F,I][$([cR1]1[cR1][cR1][cR1][cR1][cR1]1-[cR1]2[cR1][cR1][cR1][cR1][cR1]2),$([cR1]1[cR1][cR1][cR1][cR2]2[cR2]1[cR1][cR1][cR1][cR1]2)]",** +121,Halogenated dibenzodioxins,"[OR1]1[CR2]2=[CR1][CR1]=[CR1][CR1]=[CR2]2[OR1][CR2]3=[CR1][CR1]([F,Cl,Br,I])=[CR1][CR1]=[CR2]13",*C1=CC=C2OC3=CC=CC=C3OC2=C1 +122,Primary and secondary aromatic amines,"[$([a!r0][NX3;H2]),$([a!r0][NX3;H1][CH3]),$([a!r0][NX3;H1][CH2][CH3])]",* +123,Tertiary aromatic amines,"a[NX3]([$([CH3]),$([CH2][CH3])])[$([CH3]),$([CH2][CH3])]",*N(*)* +124,Secondary aromatic acetamides and formamides,"[$([a!r0][NX3;H1][CX3;H1](=[OX1])),$([a!r0][NX3;H1][CX3](=[OX1])[CH3])]",* +125,Nitroarenes,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=O)(=O))]",** +126,Nitrosoarenes,[a!r0][NX2]=[OX1],*N=O +127,Arylhydroxylamines,"[a!r0][NX3;H1][OX2][#1,#6]",*NO* +128,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O +129,N-Nitroso-N-alkylamides,"[CX4,a!r0][CX3](=[OX1])[NX3]([CX4])[NX2]=[OX1]",*C(=O)N(C)N=O +130,N-Nitroso-N-alkylureas,"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[NX3H1][CX4,a!r0]",*[NH]C(=O)N(C)N=O +131,N-Nitroso-N-alkylcarbamates (aka urethanes),"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)N(C)N=O +132,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O +133,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O +134,Benzylic halides,"[a!r0][CH2][Cl,Br,I]",*[CH2]* +135,Oxiranes and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +136,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +137,Alkyl esters of sulfonic and sulphuric acids,"[$([CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,a!r0][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])])]",* +138,Alkyl esters of phosphonic and phosphoric acids,"[$([CX4,a!r0][Pv5X4](=[OX1])([OX2][$([CH3]),$([CH2][CH3])])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,#1][OX2][Pv5X4](=[OX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])])]",* +139,Mixed alkyl esters of thiophosphoric acid,"[CX4][OX2][Pv5X4](=[SX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])]",*OP(=S)(O*)OC +140,Haloethylamines,"[NX3]([#1,#6])([#1,#6])[CH2][CH2][Cl,Br,I,F]",*[CH2][CH2]N(*)* +141,Haloalkylethers,"[$([#6][OX2][CH2][CH2][Cl,Br,I]),$([#6][OX2][CH2][Cl,Br,I])]",* +142,α-Halocarbonyl or a-halohydroxy,"[$([CX3](=[OX1])[CH2][Cl,Br,I]),$([CX4!H0]([OH1])[CH2][Cl,Br,I])]",* +143,Haloamines,"[#6][NX3]([#6])[Cl,Br,I,F]",*N(C)C +144,Allylic halides and alkoxides,"[CX3]=[CX3][CH2][$([Cl,Br,I]),$([OX2])]",*[CH2]C=C +145,Halogenated methanes,"[CX4]([H,F,Cl,Br,I])([H,F,Cl,Br,I])([H,F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)* +146,Vinyl halides,"[CX3]=[CX3H1][Cl,Br,I]",*[CH]=C +147,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O +148,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S +149,Alkyl esters of phosphonic or sulphonic acids,"[$([CX4,a][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]),$([CX4,a][Pv5X4](=[OX1])([OX2][#1,CX4])[OX2][CX4])]",* +150,Aromatic nitro groups,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=[OX1])=[OX1]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +151,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +152,Aromatic mono- and dialkylamino groups,"[a!r0][$([NX3H1][CH3]),$([NX3H1][CH2][CH3]),$([NX3]([CH3])[CH3]),$([NX3]([CH3])[CH2][CH3]),$([NX3]([CH2][CH3])[CH2][CH3]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +153,Alkyl hydrazines,"[NX3]([CX4])([#1,CX4])[NX3]([#1,CX4])[#1,CX4]",*N(*)N(*)C +154,Alkyl aldehydes,"[$([CX3]([H])(=[OX1])[#1,CX4])&!$([CX3]([H])(=[OX1])[CX3]=[CX3])]",* +155,Monohaloalkenes,"[CX3]([CX4,#1])(Cl)=[CX3]([!F!Cl!Br!I])[CX4,#1]",*C(*)=C(*)Cl +156,"β-Haloethyl N, S - mustards","[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +157,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl +158,Propiolactones and propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +159,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1 +160,Aromatic and aliphatic substituted primary alkyl halides,"[F,Cl,Br,I][CH2][CX4,a]",*[CH2]* +161,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O +162,Aliphatic and aromatic epoxides,"[$([CX4]1[OX2][CX4]1),$([#6]1=[#6][#8]1)]",* +163,Activated halo- or nitropyridines,"[$(c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])cc1),$(c1([F,Cl,Br,I,$(N(=O)=O)])ncccc1([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)]))]",* +164,2-Halo- or 2-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncccn1",*c1ncccn1 +165,4-Halo- or 4-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncncc1",*c1ccncn1 +166,Activated 2-halo- or 2-nitropyrazines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])nc1",*c1cnc(*)cn1 +167,Halo- or nitro s-triazines,"c1nc([F,Cl,Br,I,$(N(=O)=O)])ncn1",*c1ncncn1 +168,Formaldehyde and thioformaldehyde,"[CH2]=[OX1,SX1]",*=C +169,Aliphatic aldehydes and thioaldehydes,"[CX4][CX3H1]=[OX1,SX1]",*=[CH]C +170,Aromatic aldehydes,[a][CX3H1]=[OX1],*[CH]=O +171,"α, β-Unsaturated carbonyl and thiocarbonyl compounds","C(C)(C)=CC=[OX1,SX1]",*=CC=C(C)C +172,"α, β-Unsaturated ketones and thioketones","[C;!r5]([C;!r5])=[C;!r5][C;!r5](C)=[OX1,SX1;!r5]",*=C(C)C=CC +173,α-Diketones and α-dithiones,"[#6]C(=[OX1,SX1])C(=[OX1,SX1])[#6]",*=C(C)C(=*)C +174,β-Diketones and β-dithiones,"[#6]C(=[OX1,SX1])[CX4]C(=[OX1,SX1])[#6]",*=C(C)CC(=*)C +175,"C-Nitroso compounds, iso(thio)cyanates, (thio)cyanate esters","[#6][$([NX2]=O),$(N=C=O),$(OC#N),$(SC#N),$(N=C=S)]",*C +176,Primary alkyl amines,[CH2][NH2],[CH2][NH2] +177,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3] +178,"α, β-Unsaturated alkoxy","[$(CC(C)=[CH][CH2][OH]),$(CC=C(C)[CH2][OH])]",* +179,Three-membered heterocycles derivatives,"[CH,CH2,CH3;!$([CH2]CC=[O,S])]([F,Cl,Br,I,$(OS(=O)(=O)[#6,#1]),$(OS(=O)(=O)O[#6,#1])])[#6]1[O,N,SX2][#6]1",**C1*C1 +180,Lactones and their thio analogues,"C1C(=[O,S])[O,S][CH2,CH]1",*=C1**C1 +181,Esters of aromatic and unsaturated alcohols and their thio analogues,"[$(C=C),$(C#C),a][CH2,CH][O,S][$([CH]=O),$([CH]=S),$(C(C)=O),$(C(C)=S)]",**** +182,Aryloxy (arylthio) containing unsaturated compounds,"[$(C=C),$(C#C),a][CH2,CH][O,S][a]",**** +183,Aliphatic N-(thio)nitroso compounds,"[CH2,CH3][NX3][NX2]=[O,S]",*NN=* +184,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1 +185,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +186,Activated alkene (Michael acceptor) (1),"[CH2,CH]=[CH][$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*[CH]=* +187,Activated alkene (Michael acceptor) (2),"[CH2]=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C +188,Activated alkene (Michael acceptor),"aC=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C* +189,Activated alkine,"C#C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C#C +190,Activated conjugated dienes,"[CH2,CH]=[CH]C=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C[CH]=* +191,Alkenes containing a gem-dihalo-substituted terminal double bond,"C=C([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)=C +192,Ortho-disubstituted benzenes,"c1c([O,NH2,NH])c([O,NH2,NH])ccc1",*c1ccccc1* +193,Para-disubstituted benzenes,"c1c(=[O,NH2,NH])ccc(=[O,NH2,NH])c1",*=c1ccc(=*)cc1 +194,Haloanhydrides,"[F,Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +195,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1 +196,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21 +197,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +198,Phosphorus halogen derivatives (1),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#6])[#6]",*P(C)(C)=O +199,Phosphorus halogen derivatives (2),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#6]",*P(C)(O)=O +200,Phosphorus halogen derivatives (3),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#8]",*P(O)(O)=O +201,Phosphorus halogen derivatives (4),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#7])[#6]",*P(C)(N)=O +202,Phosphorus halogen derivatives (5),"[Pv5X4]([F,Cl,Br,I])([#6])([#6])=[SX1]",*P(C)(C)=S +203,Phosphorus halogen derivatives (6),"[Pv5X4]([#8])([#6])([F,Cl,Br,I])(=[SX1])",*P(C)(O)=S +204,Phosphorus halogen derivatives (7),"[Pv5X4](=[SX1])([F,Cl,Br,I])([#16])[#6]",*P(C)(S)=S +205,Phosphorus V derivatives,[Pv5X4]([!#1])([!#1])([!#1])=[NX2],*P(*)(*)=N +206,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC +207,Thiocyanates,[SX2][CX2]#[NX1],N#CS +208,Sulfonylhalides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +209,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O +210,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +211,Alkylsulfates,"[#6,#1][OX2,OH1][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]",**S(=O)(=O)OC +212,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O +213,All types of 3-valent phosphorus and similar (2),"[Pv3X3]([#8])([#8])[F,Cl,Br,I]",*P(O)O +214,All types of 3-valent phosphorus and similar (3),"[Pv3X3]([#8])([#6])[F,Cl,Br,I]",*P(C)O +215,All types of 3-valent phosphorus and similar (4),"[Pv3X3]([#6])([#6])[F,Cl,Br,I]",*P(C)C +216,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C +217,All types of 3-valent phosphorus and similar (6),"[Pv3X3]([#8])([#7])[F,Cl,Br,I]",*P(N)O +218,All types of 3-valent phosphorus and similar (7),"[Pv3X3]([#7])([#7])[F,Cl,Br,I]",*P(N)N +219,All types of 3-valent phosphorus and similar (8),"[#16][Pv3X3]([#6])[F,Cl,Br,I]",*P(C)S +220,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N +221,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C +222,Hydroxamic acid haloanhydrides,"[CX3]([#6])([F,Cl,Br])=[NX2][#8]",*C(C)=NO +223,Halothioanhydrides,"[#6][CX3](=[SX1])[F,Cl,Br,I]",*C(C)=S +224,Halocarbonates,"[#8][CX3](=[OX1])[F,Cl,Br,I]",*C(O)=O +225,Halocarbamates,"[#7][CX3](=[OX1])[F,Cl,Br,I]",*C(N)=O +226,Isocyanides,"[#6][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +227,Azides,"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +228,Thione esters,"[#6,#1][CX3](=[SX1])[OX2][#6]",*C(=S)OC +229,Acylsulfides,"[#6,#1][CX3](=[OX1])[SX2][#6]",*C(=O)SC +230,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S +231,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S +232,Peroxides,[OX2][OX2],OO +233,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS +234,Nitroso,[#6][NX2]=[OX1],CN=O +235,Nitrates,"[#6][OX2][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*OC +236,N-Nitro,"[#7][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*N +237,N-Nitroso,[#7][NX2]=[OX1],NN=O +238,Azo,[#6][NX2]=[NX2][#6],CN=NC +239,Azoxy,"[#6][$([NX2]=[NX3+]([O-])[#6]),$([NX2]=[NX3](=[OX1])[#6])]",*C +240,Nitroso dimers,"[$([#6][NX3+]([OX1-])=[NX3+]([OX1-])[#6]),$([#6][NX3](=[OX1])=[NX3](=[OX1])[#6])]",* +241,Sulfenyl halides,"[#6][Sv2X2][F,Cl,Br,I]",*SC +242,Sulfinyl halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +243,Diazonium salts,"[$([NX2+]#[NX1]),$([NX2]#N)]",* +244,Cyclic and linear haloamidines,"[CX3](=[#7])([#7])[Cl,Br,I]",*C(N)=N +245,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC +246,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C +247,Hydroxylamines,[OH1][NX3][#6],CN[OH] +248,N-Oxides,"[$([OX1-,OH1][#7X4+]([*])([*])([*])),$([OX1]=[#7X4v5]([*])([*])([*])),$([OX1]=[Nv5X3&!$([Nv5X3](=[OX1])=[OX1])](=[*])([*])),$([OX1-,OH1][#7X3+R](~[R])(~[R])),$([OX1]=[#7v5X3R](~[R])(~[R]))]",* +249,Aminals,N[CX4]N,NCN +250,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C +251,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C +252,α-Haloketones and similar,"[#6][CX3](=[OX1])[CX4][Cl,Br,I]",*CC(C)=O +253,β-Haloamines,"[NX3][CX4][CX4][Cl,Br,I]",*CCN +254,β-Halosulfides,"[Sv2X2][CX4][CX4][Cl,Br,I]",*CCS +255,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O +256,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O +257,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C +258,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O +259,Nitrovinyl,"[CX3]=[CX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +260,Acrylonitriles,[NX1]#CC=C,C=CC#N +261,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O +262,Vinylpyridines and similar,"[$(n1c([CX3]=[CX3])cccc1),$(n1cc([CX3]=[CX3])ccc1),$(n1ccc([CX3]=[CX3])cc1)]",* +263,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1 +264,Ketenes,[CX3]=[CX2]=[OX1],C=C=O +265,Allenes,C=C=C,C=C=C +266,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1 +267,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1 +268,Aziridines,[CX4]1[NX3][CX4]1,C1CN1 +269,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1 +270,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1 +271,Selen in chain,[Sev2X2],[SeH2] +272,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O +273,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N +274,Benzylhalogenides and similar,"c1ccccc1([CX4][Cl,Br,I])",*Cc1ccccc1 +275,Halomethyl ethers,"[F,Cl,Br,I][CX4][#8]",*CO +276,Halomethyl thioethers,"[F,Cl,Br,I][CX4][#16]",*CS +277,Halomethyl amines,"[F,Cl,Br,I][CX4][#7]",*CN +278,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O +279,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S +280,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S +281,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S +282,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S +283,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O +284,Positively charged N-heterocycles,[#7v4X3R],N +285,Organometallic compounds,"[$([Te]~[#6]),$([As]~[#6]),$([Ge]~[#6]),$([Hg]~[#6]),$([Co]~[#6]),$([Fe]~[#6]),$([Mn]~[#6]),$([Cr]~[#6]),$([Ti]~[#6]),$([Sn]~[#6])]",* +286,"Isothiazolinone, isothiazolinthione and their derivatives","[#6]1=,:[#6]C(=[OX1,SX1])N[SX2]1",*=C1C=CSN1 +287,Acyl and thioacyl halides,"[!$(C=C);!$(C#C)]C(=[O,SX1])[F,Cl,Br,I]",*C(*)=* +288,Imidoyl halides,"[!$(C=C);!$(C#C)]C(=N)[F,Cl,Br,I]",*C(*)=N +289,Esters of aromatic alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][a]",**C(*)=* +290,Acid anhydrides and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N]C(=[O,SX1,N])",*C(=*)*C=* +291,Esters of unsaturated alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,S,N])[O,S][$(C=C),$(C=N),$(C#C),$(C#N)]",**C(*)=* +292,"β-Lactones, β-lactams and their thio analogues","[#6]1C(=[O,S])[O,N,S][#6]1",*=C1*CC1 +293,Benzo-fused five-membered heterocycles,"[C,N,O,S,a]c1[n,o,s]c2ccccc2[n,o,s]1",*c1*c2ccccc2*1 +294,(Thio)carbonyl and imine derivatives of five-membered heterocycles,"[#6]1[#6](=[N,O,S])[#7,#8,#16][#6][#7,#8,#16]1",*=C1*C*C1 +295,Phthalic anhydrides and their thio and aza analogues,"[C,O]=[#6]1[#7,#8,#16][#6](=[O,N,SX1])c2ccccc12",*=C1*C(=*)c2ccccc21 +296,Acylating agents,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][CX4,O,S][$(C=O),a,$(C=C),$(C#C),$(C=N),$(C#N)]",***C(*)=* +297,Heteryl-substituted benzenes,"C1=[C,N][$(S(=O)(=O)),$(C=[N,O]),$(S=O)][C,N]=C1c2ccccc2",*1*=CC(c2ccccc2)=*1 +298,Cyclopentanone and cyclopentathione derivatives,"[CH2,CH]=C1C(=[OX1,SX1])**C1",*=C1**CC1=* +299,"Ortho-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])c([OH,NH2,NH,$(N=N),$(N(C)C)])ccc1",*c1ccccc1* +300,"Para-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])ccc([OH,NH2,NH,$(N=N),$(N(C)C)])c1",*c1ccc(*)cc1 +301,"Meta-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])cc([OH,NH2,NH,$(N(C)C)])cc1",*c1cccc(*)c1 +302,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH] +303,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1 +304,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1 +305,Haloethyl-substituted aromatic compounds,"C([F,Cl,Br,I])[CH2,CH][a]",**C* +306,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1 +307,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1 +308,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12 +309,vic-Difluoroalkyl group,"F[CH2,CH]C(F)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(F)*F +310,vic-Dichloroalkyl group,"Cl[CH2,CH]C(Cl)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Cl)*Cl +311,vic-Dibromoalkyl group,"Br[CH2,CH]C(Br)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Br)*Br +312,vic-Diiodoalkyl group,"I[CH2,CH]C(I)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(I)*I +313,Carboxylic acid anhydrides,"[$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6]1),$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6][#6]1)]",* +314,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl +315,Lactones,"[$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6]1),$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6][#6]1)]",* +316,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O +317,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC +318,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC +319,Cyclic sulfonic acid esters,"[$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +320,Cyclic sulfuric acid esters,"[$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +321,Halo acetates,"[F,Cl,Br,I][#6][CX3](=[OX1])[OX2H1]",*CC(=O)[OH] +322,Halo acetamides,"[F,Cl,Br,I][#6][CX3](=[OX1])[NX3]",*CC(N)=O +323,Halo ethers,"[$([F,Cl,Br,I]C[OX2]C),$([F,Cl,Br,I]CC[OX2]C)]",* +324,Haloethyl sulfides (S-mustard),"[F,Cl,Br,I][CX4][CX4][SX2]",*CCS +325,Haloethyl amines (N-mustard),"[F,Cl,Br,I][CH2][CH2][NX3]",*[CH2][CH2]N +326,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O +327,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N +328,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C +329,"α, β-Unsaturated nitro compounds","[#6]=[#6][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +330,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O +331,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C +332,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH] +333,"α, β-Unsaturated carbonyl compounds",[#6]=[#6][CX3](=[OX1])([!#1!$([OH1])]),*C(=O)C=C +334,Alkyl halide,"[*!$([a])&!$(C=C)&!$(C#C)][CX4][F,Cl,Br,I]",*C* +335,Aryl halide,"[a!r0][F,Cl,Br,I]",** +336,Halogenated allylic group,"[F,Cl,Br,I][CX4][CX3]=[CX3]",*CC=C +337,Halogenated benzylic group,"c[CX4][F,Cl,Br,I]",*Cc +338,Diazo compounds,"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +339,Organo metallic compounds,"[$([Cu][#6]),$([Ag][#6]),$([Au][#6]),$([Zn][#6]),$([Cd][#6]),$([Hg][#6]),$([Sn][#6]),$([Pb][#6]),$([As][#6]),$([Sb][#6])]",* +340,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C +341,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C +342,Iodine,II,II +343,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H] +344,Sulfoxides,[Sv4X3](=[OX1]),O=S +345,Sulfenyl iodides,[SX2][IX1],SI +346,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS +347,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S +348,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS +349,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH] +350,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1 +351,(Dithio) carbamates,"[OX2,SX2][CX3](=[OX1,SX1])[NX3]",*C(=*)N +352,Organotin compounds,[Sn][#6],C[Sn] +353,Pyrethroids,"[$(CC(=C[CH]1C([CH]1C(=O)OC1C(=C(C(=O)C1)CC=CC=C)C)(C)C)C),$(C(=C[CH]1C([CH]1C(=O)O[CH]1C(=C(C(=O)C1)CC=CC=C)C)(C)C)(C)C(=O)OC)]",* +354,Organophosphorothionate esters,"[Pv5X4](=[SX1])([OX2][#6])([OX2,SX2][#6])([OX2,SX2][#6])",C*P(=S)(*C)OC +355,Acetates,"[CH,$([C!R](=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R,NX3!R][$([a;r6]),$([a;r5]),$(C=C),$(C#C)]",***=* +356,Acyclic anhydrides,"[CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R][CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])]=[O,SX1]",*=***=* +357,Dialkyl carbamoylhalides,"[NH2!R,$([NH!R](C=O)[#6!R]),$(N(C=O)([#6!R])[#6!R])]C(=O)[F,Cl,Br,I]",*C(*)=O +358,Phosphonic acid halides,"[#6]O[P!R](=O)(O[#6])[F,Cl,Br,I,$(C#N)]",*P(=O)(OC)OC +359,Cyclopropenones,"[#6]1([#1,#6])=,:[#6]([#1,#6])-,:[#6]1=O",*C1=C(*)C1=O +360,β-Lactones,C1C(=O)OC1,O=C1CCO1 +361,Thio-lactones,C1C(=O)SC1,O=C1CCS1 +362,Azlactones,"C1=[O,SX2,NX2,CX3]CC(=[O,SX2])[O,SX2,NX3]1",*=C1*C=*C1 +363,Cyclic anhydrides,"[#6R,#8R,#16X2R][#6R](=[O,SX1])[#8R,#16X2R][#6R]([#6,#8R,#16X2])=[#8,#16X1]",*C(=*)*C(*)=* +364,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC +365,Polarised alkene-aldehydes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][CH]=O",*=*[CH]=O +366,Polarised alkene-ketones,"[$([$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[#6]);!$([#6X3]1=,:[#6X3H][CX3](=[OX1])[#6X3]=,:[#6X3][#6X3]1(=[OX1]));!$([CX3]1(=[OX1])[CX3](=[OX1])[#6X3]=,:[#6X3H][#6X3]=,:[#6X3]1)]",* +367,Polarised alkene-esters,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)O[#6]",*=*C(=O)OC +368,Polarised alkene-amides,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)*=* +369,Polarised alkene-nitros,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",**=* +370,Polarised alkene-cyanos,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C#N",*=*C#N +371,Polarised alkene-alkyl sulphonates,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)O[#6]",*=*S(=O)(=O)OC +372,Polarised alkene-alkyl sulfones,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)[#6]",*=*S(C)(=O)=O +373,Polarised alkene-alkyl sulfinyls,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][SX3](=O)[#6]",*=*S(C)=O +374,Polarised alkene-oximes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C=[NX2][OH]",*=*C=N[OH] +375,Polarised alkene-pyridines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncccc1),$(c1ccncc1)]",**=* +376,Polarised alkene-pyrazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]c1nccnc1",*=*c1cnccn1 +377,Polarised alkene-pyrimidines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncc1),$(c1ncccn1),$(c1cncnc1)]",**=* +378,Polarised akene-triazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1),$(c1nnncc1),$(c1cnnnc1)]",**=* +379,Azocarbonamides,"[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]C(=O)N=NC(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)N=NC(*)=O +380,Allyl alcohols,"[CH2,$([CH](=C)[#6])]=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",*=*[CH2][OH] +381,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH] +382,Polarised alkyne-aldehydes,"[CH,$(C(#C)[#6])]#C[CH]=O",*#C[CH]=O +383,Polarise alkyne-ketones,"[CH,$(C(#C)[#6])]#CC(=O)[#6]",*#CC(C)=O +384,Polarised alkyne-esters,"[CH,$(C(#C)[#6])]#CC(=O)O[#6]",*#CC(=O)OC +385,Polarised alkyne-amides,"[CH,$(C(#C)[#6])]#CC(=O)[$([NH2]),$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)C#* +386,Polarised alkyne-nitros,"[CH,$(C(#C)[#6])]#C[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C#* +387,Polarised alkyne-cyano,"[CH,$(C(#C)[#6])]#CC#N",*#CC#N +388,Polarised alkyne-alkyl sulphonates,"[CH,$(C(#C)[#6])]#CS(=O)(=O)O[#6]",*#CS(=O)(=O)OC +389,Polarised alkyne-alkyl sulfones,"[CH,$(C(#C)[#6])]#CS(=O)(=O)[#6]",*#CS(C)(=O)=O +390,Polarised alkyne-alkyl sulfinyls,"[CH,$(C(#C)[#6])]#C[SX3](=O)[#6]",*#CS(C)=O +391,Polarised alkyne-pyridines,"[CH,$(C(#C)[#6])]#C[$(c1ncccc1),$(c1ccncc1)]",*C#* +392,Polarised alkyne-pyrazines,"[CH,$(C(#C)[#6])]#Cc1nccnc1",*#Cc1cnccn1 +393,Polarised alkyne-pyrimidines,"[CH,$(C(#C)[#6])]#C[$(c1ncccn1),$(c1cncnc1),$(c1ncncc1)]",*C#* +394,Polarised alkyne-triazines,"[CH,$(C(#C)[#6])]#C[$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1)]",*C#* +395,Propargyl alcohols,"[CH,$(C(#C)[#6])]#C[CH2][OH]",*#C[CH2][OH] +396,Benzoquinones,"[$(C1(=O)[#6]=,:[#6]C(=O)[CH]=C1),$(C1(=O)C(=O)[#6]=,:[#6][CH]=C1)]",* +397,Quinone-imines,"[$(C1(=O)[#6]=,:[#6][$(C=[NH]),$(C=N[CX4])][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])]C=[CH][#6]=,:[#6]1)]",* +398,Quinone-diimines,"[$([CH]1=C[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][$(C=[NH]),$(C=N[CX4])]1),$([CH]1=C[$(C=[NH]),$(C=N[CX4])][$(C=[NH]),$(C=N[CX4])][#6]=,:[#6]1)]",* +399,Aminophenols,"[$(c1([OH])c[cH]c([NH2])cc1),$(c1([OH])c([NH2])cc[cH]c1)]",* +400,Benzenediamines,"[$(c1([NH2])c[cH]c([NH2])cc1),$(c1([NH2])c([NH2])cc[cH]c1)]",* +401,Quinone-methides,"[$(C1=CC(=O)[#6]=,:[#6]C1(=[CH][CX4])),$(C1(=[CH][CX4])C(=O)[#6]=,:[#6]C=C1)]",* +402,Pyranones,"[$([cH]1cc(=[O,NH])cc[o,n]1),$([cH]1cc(=[O,NH])[o,n]cc1),$(c1cc(=[O,NH])[o,n][cH]c1)]",* +403,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1 +404,Mono-aldehydes,"[CH2,$([CH](=O)[CX4]),$([CH](=O)c1a(*)caaa1),$([CH](=O)c1a(*)aaa1)]=O",*=O +405,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2] +406,"Di-substituted α,β-unsaturated alkenes (polarized by an aldehyde moiety)","[$(C(=C)([#6])[#6]);!$(C(=C)([#6])C=[CH2,CH])]=C[CH]=O",*=C[CH]=O +407,Di-substituted allyl alcohols,"C([#6])([#6])=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",CC(C)=*[CH2][OH] +408,"1,2-Dicarbonyls","[CH,$(C(=O)(C=O)[CX4]),$(C(=O)(C=O)c1a(*)aaaa1),$(C(=O)(C=O)c1a(*)aaa1)](=O)[CH,$(C(=O)(C=O)[#6]);!$(C(=O)(C=O)C=[CH2,CH]);!$(C(=O)(C=O)C#C)]=O",O=**=O +409,"1,3-Dicarbonyls","[CH,$(C(=O)([CX4]C=O)[CX4]),$(C(=O)([CX4]C=O)c1a(*)aaaa1),$(C(=O)([CX4]C=O)c1a(*)aaa1)](=O)[CX4][CH,$(C(=O)([CX4]C=O)[#6]);!$(C(=O)([CX4]C=O)C=[CH2,CH]);!$(C(=O)([CX4]C=O)C#C)]=O",O=*C*=O +410,Ethylenediamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][NH2]),$([NH]1[CH2][CH2][NH][CH2][CH2]1)]",* +411,Ethanolamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][OH]),$([NH]1[CH2][CH2]O[CH2][CH2]1)]",* +412,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1 +413,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1 +414,Alkyl halides,"[CH3,$([CH2]([F,Cl,Br,I])[#6]),$([CH]([F,Br,Cl,I])([#6])[#6]);!$([CH2,CH]C=O);!$([CH2,CH][CX4][NX3,SX2]);!$([CH2,CH][CX4][F,Cl,Br,I])][F,Cl,Br,I]",** +415,Alkyl diazos,"[CH3,$([CH2](N=N)[#6]),$([CH](N=N)([#6])[#6])][NX2]=[NH,$(N(=N)[#6])]",*N=* +416,Alkyl sulfates,"[#6]OS(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(=O)(=O)OC +417,Alkyl sulphonates,"[#6]S(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(C)(=O)=O +418,Alkyl (thio)phosphates,"[#6][O,SX2]P(=[O,SX1])([O,SX2][#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(*C)*C +419,Alkyl (thio)phosphonates,"[#6][O,SX2]P(=[O,SX1])([#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(C)*C +420,Allyl acetates,"[#6]C(=[O,SX1])[O,SX2][CH2,$([CH]([O,SX2])[#6])][c,CX3,CX2]",***C(=*)C +421,α-Halocarbonyls,"[$([CH]=[O,SX1]),$(C([#6])=[O,SX1])][CH2,$([CH](C=[O,SX1])[#6])][F,Cl,Br,I]",*** +422,α-Haloalkynes,"[CH,$(C(#C)[#6])]#C[$([CH2](C#C)[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH](C#C)([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*C#* +423,α-Halobenzyls,"[c][$([CH2]([c])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH]([a])([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*c +424,Sulfuranes,C1[SX2]C1,C1CS1 +425,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1 +426,Nitrosoureas,"[NX3]C(=O)[$([NH](C=O)[NX2]=O),$(N(C=O)([#6])[NX2]=O)]",*C(N)=O +427,Nitrosoguanidines,"[NX3]C(=[NH])[$([NH](C=[NH])[NX2]=O),$(N(C=[NH])([#6])[NX2]=O)]",*C(N)=N +428,N-Acytoxy-N-acetylphenyls,"[a][NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)* +429,N-Acytoxy-N-alkoxyamides,"[#6]O[NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)OC +430,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O +431,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O +432,Aromatic sulphonic acids,[a][SX4](=O)(=O)[OH],*S(=O)(=O)[OH] +433,Isothiazol-3-ones,"[cH,$(c(c)([sX2])[#6])]1[cH,$(c(c)(c=O)[#6])]c(=O)[nH,$(n(c=O)([sX2])[#6])][sX2]1",O=c1*:*s*1 +434,Isothiazolin-3-ones,"[CH2,$([CH](C)([SX2])[#6])]1[CH2,$([CH](C)(C=O)[#6])]C(=O)[NH,$(N(C=O)([SX2])[#6])][SX2]1",O=C1**S*1 +435,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl +436,Polarized alkenes with a halogen leaving group,"C=[CH][F,Cl,Br,I]",*[CH]=C +437,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C +438,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C +439,Polarized alkenes with an alkyl (thio)phosphonate leaving group,"C=[CH]OP(=[O,SX])(O[#6])[#6]",*=P(C)(OC)O[CH]=C +440,Polarized alkenes with an alkyl (thio)phosphate leaving group,"C=[CH]OP(=[O,SX])(O[#6])O[#6]",*=P(OC)(OC)O[CH]=C +441,Mustards,"[NX3,SX2][CH2,$([CH]([NX3,SX2])([CX4])[CX4])][CH2,$([CH]([CX4])([Cl,Br,I])[CX4])][Cl,Br,I]",**** +442,"1,2-Dihaloalkanes","[Cl,Br,I][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][Cl,Br,I]",**** +443,Activated pentafluorobenzenes,"c1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-]),$([CH]=O),$(C#N),$(C(=O)[CH3])])c(F)c(F)c(F)c(F)c1(F)",*c1c(F)c(F)c(F)c(F)c1F +444,Formaldehyde releasers (1),"[$(O1COCC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C1),$([OX2H1]CC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C[OX2H1])]",* +445,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH] +446,Formaldehyde releasers (3),"C1(=[OX1])[NX3H1]C(=[OX1])[NX3H1][CX4]1(C[OH1])[NX3H1][CX3](=[OX1])[NX3!H0][#1,#6]",*NC(=O)[NH]C1(C[OH])[NH]C(=O)[NH]C1=O +447,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH] +448,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1 +449,"Hydrazine, hydrazides","[#6,#1][NX3H1][NX3H1][#6,#1]",*[NH][NH]* +450,Nitrobenzenes,"a[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",** +451,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21 +452,Benzylamines,"[#1,CX4!R][NX3]([#1,CX4!R])[CH2]c1ccccc1",*N(*)[CH2]c1ccccc1 +453,Propargyl amines,"[#1,CX4,$(c1ccccc1)][CX2]#[CX2][NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*C#CN(*)* +454,Cyclopropyl amines,"[CX4]1[CX4][CX4]1[NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*N(*)C1CC1 +455,"N-Substituted-4-aryl-1,2,3,6-tetrahydropyridines","[NX3]1([CX4!R])[CX4][CX3]=[CX3](c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2=CCN(C)CC2)c(*)c1* +456,N-Substituted-4-arylpiperidin-4-ol,"[NX3]1([CX4!R])[CX4][CX4][CX4]([OH1])(c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2([OH])CCN(C)CC2)c(*)c1* +457,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O +458,Hydantoins (glycolylurea),"[NX3H1]1[CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NX3H1][CX3]1(=[OX1])",*C1(*)[NH]C(=O)[NH]C1=O +459,Thioureas,"[#1,#6][NX3]([#1,#6])[CX3](=[SX1])[#7]",*N(*)C(N)=S +460,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O +461,Ortho- or parahydroquinones,"[$(c1([OH1])c([OH1])cccc1),$(c1([OH1])ccc([OH1])cc1)]",* +462,Ortho- or paraquinones,"[$([#6]1(=[OX1])-,:[#6]=,:[#6]-,:[#6](=[OX1])-,:[#6]=,:[#6]1),$([#6]1(=[OX1])-,:[#6](=[OX1])-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)]",* +463,Ortho- or paraalkylphenols,"[$(c1([OH1])c([CX4]([#1,#6])[#1,#6])cccc1),$(c1([OH1])ccc([CX4]([#1,#6])[#1,#6])cc1)]",* +464,Quinone methide,"[$([OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]-,:[#6X3]1=[CX3]([#1,#6])[#1,#6]),$([OX1]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[CX3]([#1,#6])[#1,#6])-,:[#6]=,:[#6]1)]",* +465,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1 +466,3-Methylene indoles,"c1ccc([nX3]2([#1,#6]))c(c([CH2][#1,#6])c2)c1",*[CH2]c1cn(*)c2ccccc12 +467,Furans,c1ccc[oX2]1,c1ccoc1 +468,Thiophenes,c1ccc[sX2]1,c1ccsc1 +469,Thiazoles and 2-amino derivatives,"[$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([#1,CX4!R])[sX2]1),$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([NX3]([#1,CX4!R])[#1,CX4!R])[sX2]1)]",* +470,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O +471,2- or 4-Halopyridines,"[$(n1c([Cl,Br,I,F])cccc1),$(n1cccc([Cl,Br,I,F])cc1)]",* +472,Alkynes,"[#6][CX2]#[CX2][#1,#6]",*C#CC +473,Alkylhalides,"[$([CX4]([F,Cl,Br,I])([H,!F!Cl!Br!I])([H,!F!Cl!Br!I])[H,!F!Cl!Br!I]),$([CX4]([#6])([F,Cl,Br,I])([F,Cl,Br,I])[H,!F!Cl!Br!I])]",* +474,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH] +475,Fluoroethyl ethers and amines,"[$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][OX2][#1,#6]),$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][NX3][#6])]",* +476,Three-membered heterocycles,"[#6]1~[#6][#7,#8,#16]1",*1C~C1 +477,Thioles,[Sv2X2H1],[SH] +478,Chlor(brom)anhydrides,"[CX3](=[OX1])[Cl,Br]",*C=O +479,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O +480,Trihalogensubstituted ketones,"[CX3](=[OX1])[CX4]([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C=O +481,Monohalogen substituted ketones,"[CX3](=[OX1])C[Cl,Br,I]",*CC=O +482,Sulphonhalogenanhydrides,"S(=[OX1])(=[OX1])[F,Cl,Br,I]",*S(=O)=O +483,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH] +484,Phosphorus,P,P +485,Selen,[Se],[SeH2] +486,Bor,B,B +487,Silicium,[Si],[SiH4] +488,"Isocyanates, isothiocyanates","[NX2]=[CX2]=[OX1,SX1]",*=C=N +489,Thione,[CX3]=[SX1!R],C=S +490,β-halogen substituted carbonyls,"[CX3](=[OX1])CC[F,Cl,Br,I]",*CCC=O +491,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH] +492,gem-Dihalo propane and cyclopropane,"CC([Cl,Br,I])([Cl,Br,I])C",*C(*)(C)C +493,Activated halides (o-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cc[F,Cl,Br]",*cc* +494,Activated halides (p-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cccc[F,Cl,Br]",*cccc* +495,Activated halides (α-halogen substituted N-heterocycles),"nc[F,Cl,Br]",*cn +496,Activated halides (γ-halogen substituted N-heterocycles),"nccc[F,Cl,Br]",*cccn +497,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S +498,Barbiturates,"N1C(=[OX1,SX1])NC(=[OX1,SX1])C(=C)C1(=[OX1,SX1])",*=C1NC(=*)C(=C)C(=*)N1 +499,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2] +500,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O +501,Crown ethers,[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C,*C~C*C~C*C~C*C~C*C~C*C~C +502,Coumarins (1),"c1cccc2c1oc(=O)c([$(C=[OX1]),$(C=[SX1]),$(S=[OX1]),$(C#[NX1]),F,Cl,Br,I,$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]));!$([CX3](=[OX1])[OH1])])[c!H0]2",*c1cc2ccccc2oc1=O +503,Coumarins (2),"[cH1]1[cH1]c2c3[cH1][cH1]c(cc3oc(=O)c2[cH1]c1[OX2][$([CH2]),$([CH3])])[OX2][C!H0]",*Oc1[cH][cH]c2c([cH]1)c(=O)oc1cc(OC)[cH][cH]c12 +504,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1 +505,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1 +506,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1 +507,Coumarins (6),"c1([F,Cl,Br,I])cc([F,Cl,Br,I])cc2c1oc(=[NX2H1])c([CX3](=[OX1])[NH2])[c!H0]2",*c1cc(*)c2oc(=N)c(C([NH2])=O)cc2c1 +508,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1 +509,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1 +510,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O +511,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N +512,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O +513,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N +514,o-Quinones (3),"CC(=[OX1])C(=[OX1])[#6,#7]",*C(=O)C(C)=O +515,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S +516,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12 +517,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O +518,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH] +519,N-N Single bound not in a ring,[N!R][N!R],NN +520,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC +521,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O +522,Acyl and sulfinyl cyanide,"[$(C(=[OX1])[CX2]#[NX1]),$(S(=[OX1])[CX2]#[NX1])]",* +523,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1 +524,Hydrazine and other nucleophilic NH2-groups,"[NX3H2][#7,#8]",*[NH2] +525,Activated halo- and sulfonyl-aromatics,"c1([F,Cl,Br,I,$(C(C)=NO),$([CX2]#[NX1]),$([CX3]=[OX1]),$([CX4](F)(F)F),$([SX4](=[OX1])=[OX1]);!$([CX3](=[OX1])[OH1])])na([F,Cl,Br,I,$([SX4](=[OX1])(=[OX1])C)])a([!#7])a([!#7])a1",**1:*c(*)n*(*):*:1* +526,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O +527,Acyclic gem-dihalosubstituted carbon atom,"[C!R]([Cl,Br,I])[Cl,Br,I]",*C* +528,Imines,"[N!R]=[C,N]",*=N +529,Michael acceptors (carbonyl containing acrylonitrile derivatives),C[CX3H1]=[CX3!R](C(=[OX1])[!#1]~[!#1])[CX2]#[NX1],*~*C(=O)C(C#N)=[CH]C +530,Over halogenated rings,"a1c([F,Cl,Br,I])c([F,Cl,Br,I])ac([F,Cl,Br,I])a1",*c1*:*c(*)c(*)*1 +531,o-Quinones (1),"[CX3]1(=[!#1!#6])[CX3](=[!#1!#6])[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1",*=C1C=CC=CC1=* +532,o-Quinones (2),CC(=[!#1!#6;!R])C(=[!#1!#6;!R])C,*=C(C)C(=*)C +533,o-Quinones (4),CC(=[!#1!#6;!R])S(=[OX1])(=[OX1]),*=C(C)S(=O)=O +534,p-Quinones (1),"[#6X3]1=,:[#6X3][CX3](=[!#1!#6])[#6X3]=,:[#6X3][#6X3]1(=[!#1!#6])",*=C1C=CC(=*)C=C1 +535,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3 +536,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3 +537,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1 +538,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23 +539,Acid anhydrides and analogues,[!#1](=O)O[!#1]=O,O=*O*=O +540,Acyl halides and analogues,"[C,S](=[O,S])[F,Br,Cl,I]",**=* +541,Cyano carbonyl compounds ,N#CC(=O),N#CC=O +542,Methylendiamines (1),"[!$([C,S]=O)]N([!$([C,S]=O)])[CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*N(*)CN(*)* +543,Methylendiamines (2),"[!$([C,S]=O)][NH][CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*[NH]CN(*)* +544,Methylendiamines (3),"[!$([C,S]=O)][NH][CX4][NH][!$([C,S]=O)]",*[NH]C[NH]* +545,N-Acetoxy amines and their thio analogues,"[#7][#8][C,S]=O",NO*=O +546,α-Halogen substituted N-heterocycles,"[F,Br,Cl,I]-cn",*cn +547,Activated haloaromatics,"[F,Cl,Br,I][$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",** +548,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N +549,Benzyl ammoniums,cC[NX4+],cC[N+] +550,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O +551,Cations,"[#6+,#17+,#53+,#15+,#16+]",* +552,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N +553,Halogen-bonded heteroatoms,"[!#1&!#6][F,Cl,Br,I]",** +554,Cumulated double bonds,"[C,N]=C=[C,O,N,S]",*=C=* +555,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O +556,Singel acyclic N-N bonds,[#7]!@-N,N~N +557,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N +558,Activated double bonds (2),[!c][C!H0]=CC=O,*C=CC=O +559,Activated double bonds (3),"[C!H0]=C[S,N]=O",C=C*=O +560,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O +561,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS +562,Acetoxy group attached to the substituted aromatic ring,"C(=O)O[$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",*OC=O +563,"Oxetanes, thietanes","C1[O,S]CC1",*1CCC1 +564,Trihalomethyl ketones,"CC(=O)C([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C(C)=O +565,Phosphonates,[#6]P(=O)O[#6],COP(C)=O +566,Phosphorus containing compounds ,"NP(=[N,O,S])",*=PN +567,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +568,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O +569,"C, N, O, P and S atoms in unusual valence states","[#6!v4+0,#7!v3+0,#8!v2+0,#15!v3!v5+0,#16!v2!v4!v6+0]",* +570,Sulfurous acid esters,[!#1]OS(=O)O,*OS(O)=O +571,Heteroatom-bonded thiocarbonyls,"C(=S)[O,S,N]",*C=S +572,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS +573,Thiocarbonyls,C(=S)[!#1!H0],*C=S +574,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O +575,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F +576,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O +577,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1 +578,Double acyclic N=N and N=S bonds,"[NR0,SR0]=[NR0]",*=N +579,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1 +580,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC +581,"Iodosos, chlorosos","[Cl,I]=O",*=O +582,Acid grops,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +583,Phosphocyanates,PC#N,N#CP +584,α-Hydroxy nitriles,N#CC[OH],N#CC[OH] +585,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O +586,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO +587,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N +588,Nitrites,[!#1]ON=O,*ON=O +589,Nitroso compounds,[NX2]=O,N=O +590,"Any atoms except organogens, halogens, P, S, K, Na, Mg, Ca",[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +591,Double P=S and P=C bonds,"P=[S,#6]",*=P +592,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F +593,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +594,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1 +595,Phosphorus derivatives,[P!v5],P +596,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C +597,Carboxylic acid esters,[CX4]C(=O)O[#6][!#1],*COC(C)=O +598,"N,N-Dialkyl aniline derivatives (1)","[CX4][NX3]([CX4])c1cc([$([CX4]),$(O[CX4][CX4])])c([#7])[cH]c1",*c1cc(N(C)C)c[cH]c1N +599,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1 +600,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1 +601,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1 +602,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1 +603,"N,N-Dialkyl aniline derivatives (4)","[CX4]N([CX4])c1ccc([CX4][$([OH]),$(C=[C!H0]),$(N[CX4])])cc1",*Cc1ccc(N(C)C)cc1 +604,"N,N-Dialkyl aniline derivatives (5)","[CX4]N([C!H0])c1[cH][cH]c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH][cH]1 +605,"N,N-Dialkyl aniline derivatives (6)","[CX4]N([C!H0])c1[cH]c([CX4])c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH]c1C +606,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O +607,Five-membered heterocycles (1),"C1(=C)C(=O)[#7,#8,#15,#16]N=C1",C=C1C=N*C1=O +608,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O +609,Six-membered heterocycles,"[#7,#8,#15,#16]~C1~[#7,#8,#15,#16]~C[#7,#8,#15,#16][CX3](=[#7,#8,#15,#16])[CX3]1(=[C!H0])",*~C1C(=C)C(=*)*C~*~1 +610,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1 +611,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC +612,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH] +613,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1 +614,"1,2-Diimines, 1,2-diketones and their thio- and phospho-analogues","[#6][#6](=[#7,#8,#15,#16])[#6](=[#7,#8,#15,#16])[#6,Sv6]",*C(=*)C(=*)C +615,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21 +616,NH-Indoles,"[nH]1c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1[nH]c2ccc[cH]c2c1C +617,N-Alkyl substituted indoles,"n1([CH2])c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1c(C)c2[cH]cccc2n1[CH2] +618,Macrocycles,"[*r10,*r11,*r12,*r13,*r14,*r15,*r16,*r17,*r18,*r19,*r20,*r21,*r22,*r23,*r24,*r25,*r26,*r27,*r28,*r29,*r30]",* +619,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH] +620,N-Allophanoylamides and their thio analogues,"NC(=[O,S])NC(=[O,S])NC=[O,S]",*=CNC(=*)NC(=*)N +621,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1 +622,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21 +623,N-Phenylpyrrole derivatives,N1(c2[!#1]cccc2)C([CX4])=C[C!H0]=C1[CX4],CC1=CC=C(C)N1c1cccc*1 +624,"Quinones, quinone-(di)imines and their thio- and phospho-analogues","[#7,#8,#15,#16]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[#7,#8,#15,#16])-,:[#6]=,:[#6]1",*=C1C=CC(=*)C=C1 +625,Five-membered heterocycles (2),"[#7]=C1S[CH]=C([$([CH2]),$(c:c)])N1",*C1=[CH]SC(=N)N1 +626,Five-membered heterocycles (3),"[#7]=C1SC([$([CH2]),$(C=O)])=C([$([CH2]),$(c:c)])N1",*C1=C(*)SC(=N)N1 +627,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c +628,Acethylenes,"[CH2,CH3]C#C[CH2,CH3]",*C#C* +629,α-Halonitriles,"[F,Cl,Br,I][CX4][CX2]#[NX1]",*CC#N +630,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N +631,Benzthiozolium like compounds,"[#7,#8,#16]1-,:[#6]=,:[#6]-,:[#7+]2=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6]21",*1C=C[N+]2=**=**=C12 +632,Cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +633,Di-carbonyls,"[#1,#6][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(*)=O +634,Haloalkyl,"[C!H0]([#1,#6,#7,#8,#16])[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])[Cl,Br,I]",*CC(*)(*)* +635,"Haloalkyl group attached to S, N or O atoms","[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])([Cl,Br,I])[#7,#8,#16]",*C(*)(*)* +636,Haloethylenes,"[CX3!H0]=[CX3]([#1,Cl,Br,I])[Cl,Br,I]",*C(*)=C +637,Halopyridines,"c1([F,Cl,Br,I])n[c,n][c,n][c,n][c,n]1",*c1*:*:*:*n1 +638,Heptanes,"[CH3][CH2][CH2][CH2][CH2][CH2][CH2,CH3]",*[CH2][CH2][CH2][CH2][CH2][CH3] +639,N-Oxides (six-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1)]",* +640,N-Oxides (five-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1)]",* +641,Phosphorus cations,[#15+],[PH4+] +642,Peroxide like compounds,"O[F,Cl,Br,I]",*O +643,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O +644,Double P=O bonds,[#15]=O,O=P +645,Pyridinium like compounds,"[#6][#7+]1=,:[#6]-,:[#6,#7]=,:[#6]-,:[#6,#7]=,:[#6]1",C[N+]1=C*=C*=C1 +646,Quinolizinium like compounds,"[#6,#7]1=,:[#6,#7]-,:[#6,#7]=,:[#7+]2-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6]2=,:[#6,#7]1",*1=**=[N+]2*=**=*C2=*1 +647,Sulfates,"[Sv6X4](=[OX1])(=[OX1])([#8])[#6,#8]",*S(O)(=O)=O +648,Thio aldehydes,"[#6,#1][CX3]([H])=[SX1]",*C([H])=S +649,Thio halogens,"[#16][F,Cl,Br,I]",*S +650,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH] +651,Thiozolium like compounds,"[#6][#7+]1=,:[#6]-,:[#7,#8,#16]-,:[#6]=,:[#6]1",C[N+]1=C*C=C1 +652,Acyl Halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +653,Sulphonyl Halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +654,Alkyl Halides,"[CX4][F,Cl,Br,I]",*C +655,Activated Halides,"[$(c([F,Cl,Br,I])c[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])aac[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])n),$(c([F,Cl,Br,I])aan)]",* +656,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +657,Aldehydes (including aminoformyl moieties),"[$([#1,#6][CX3]([H])=[OX1]),$([#7]([#1,#6])([#1,#6])[CX3H1]=[OX1])]",* +658,Nitrosos,[NX2]=[OX1],N=O +659,Picrates,"c1([OH1,O-])c([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])",*c1cc(*)c(*)c(*)c1 +660,Perchlorates (periodates),"[$([Clv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-]),$([Iv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-])]",* +661,Simple anilines and phenols,"[$(c1([NX3]([#1,#6])[#1,#6])ccccc1),$(c1([OH1])ccccc1)]",* +662,Vinyl ketones (Michael acceptors),[CX3]([!R])([!R])=[CX3][CX3](=[OX1])[!$([OH1])!$([OX2][CH2])!$([NH2])!$([CX2]#[NX1])!a],*C(=O)C=C(*)* +663,Metals,[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +664,Non-organic chemistry atoms,[!#6!#1!#7!#8!#9!#17!#35!#53!#15!#14!#16],* +665,Atoms not supported in ALOGPS program,[!#1!#6!#7!#8!#16!#15!#9!#17!#35!#53],* +666,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F +667,Carbonyl compouns: aldehydes or ketones,"[$([H][CX3]([#1,#6])=[OX1]),$([#6&!$(C#N)][CX3](=[OX1])[#6&!$(C#N)])]",* +668,Thiocarbonyl compounds: thioaldehydes or thioketones,"[$([#1,#6][#6X3](=[SX1])[#1,#6]),$([#6]=[CX2]=[Sv2X1])]",* +669,Thioaldehydes,"[#1][CX3]([#1,#6])=[SX1]",*C([H])=S +670,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S +671,Hydrazones,"[CX3]([#1,#6])([#1,#6])=[NX2][#7X3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)* +672,Semicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=O)N(*)* +673,Thiosemicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=S)N(*)* +674,Oximes,"[#1,#6][CX3]([#1,#6])=[NX2][OH1]",*C(*)=N[OH] +675,Oxime ethers,"[#1,#6][CX3]([#1,#6])=[NX2][OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NOC +676,Ketene acetal derivatives,"[#1,#6][CX3]([#1,#6])=[CX3]([!#6!#1])[!#6!#1]",*C(*)=C(*)* +677,Carbonyl hydrates,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OH1]",[OH]*[OH] +678,Hemiacetals / Hemiketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*[OH] +679,Acetals / Ketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*OC +680,Hemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,*])[#1,*]",*O*N(*)* +681,Thiohemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[NX3]([#1,*])[#1,*]",*S*N(*)* +682,Thioacetals / Thioketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[SX2,OX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)]",C**SC +683,Enols,"[CX3]([#1,#6])([#1,#6])=[CX3]([OH1])[#1,#6]",*C(*)=C(*)[OH] +684,Enolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([OX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]",*C(*)=C(*)OC +685,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH] +686,Alcohols,"[$([CX4][OH1])&!$(C([OH1])[#7,#8,#15,#16,F,Cl,Br,I])]",* +687,Primary alcohols,"[$([#6][CH2][OH1]),$([CH3][OH1])]",* +688,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH] +689,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH] +690,"1,2-Diols","[CX4]([OH1])([#1,#6])([#1,#6])[CX4]([OH1])([#1,#6])([#1,#6])",*C(*)([OH])C(*)(*)[OH] +691,"1,2-Aminoalcohols","[CX4]([#1,#6])([#1,#6])([OH1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([CX4][CX4][OH1])[#6&!$([CX3]=[OX1,SX1,NX2,C])])]",*C(*)(*)C(*)(*)[OH] +692,Phenols,c[OH1],c[OH] +693,Diphenols,"[$(c([OH1])c([OH1])),$(c([OH1])[aR1]c([OH1])),$(c1([OH1])aac([OH1])aa1)]",* +694,Enediols,"[CX3]([#1,#6])([OH1])=[CX3]([#1,#6])([OH1])",*C([OH])=C(*)[OH] +695,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC +696,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc +697,Diarylethers,c[OX2&!$([OX2r3])]c,cOc +698,Hydroperoxides,"[#1,#6][OX2][OX2H1]",*O[OH] +699,Hydrazine derivatives,"[$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])][$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])]",** +700,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +701,Primary aromatic amines,[NX3H2]c,c[NH2] +702,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C +703,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C +704,Secondary aromatic amines,[NX3H1](c)c,c[NH]c +705,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C +706,Tertiary mixed amines (aryl alkyl),"c[NX3]([CX4&!$([CX4]([NX3])[O,N,S,P])])[c,CX4&!$([CX4]([NX3]c)[O,S,N,P])]",*N(c)C +707,Quaternary ammonium salts,"[NX4,NX4+]([#6])([#6])([#6])[#6]",C*(C)(C)C +708,"Halogen derivatives (alkyl, alkenyl, aryl)","[CX4,CX3,c;!$([#6]=[OX1])][F,Cl,Br,I]",** +709,Aryl fluorides,aF,*F +710,Aryl chlorides,aCl,*Cl +711,Aryl bromides,aBr,*Br +712,Aryl iodides,aI,*I +713,Organolithium compounds,[Li][#6],[Li]C +714,Organomagnesium compounds,[Mg][#6],C[Mg] +715,Carboxylic acid derivatives,"[#1,#6][CX3](=[OX1])[!#1!#6!$([SH1,SX2])]",*C(*)=O +716,Carboxylic acid salts,"[#1,#6][CX3](=[OX1])[OX1-]",*C(=O)[O-] +717,Carboxylic acid amides,"[#1,#6][CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=O)N(*)* +718,Carboxylic acid primary amides,"[#1,#6][CX3](=[OX1])[NX3H2]",*C([NH2])=O +719,Carboxylic acid secondary amides,"[#1,#6][CX3](=[OX1])[NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)[NH]C +720,Carboxylic acid tertiary amides,"[#1,#6][CX3](=[OX1])[NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)N(C)C +721,Lactams,"[#6R][CX3R](=[OX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=O +722,Carboxylic acid hydrazides,"[$([#6,#1][#6X3](=[OX1])[#7X3&!$([#7X3]([*]=[OX1,SX1])[#7X3]([*]=[OX1,SX1]))][#7X3]),$(C1(=O)[NX3][NX3]C(=O)cc1)]",* +723,Carboxylic acid azides,"[#1,#6][CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C(*)=O +724,Hydroxamic acids,"[#1,#6][CX3](=[OX1])[NX3][OH1]",*C(=O)N[OH] +725,Carboxylic acid amidines,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,N])]",*N=C(*)N(*)* +726,Carboxylic acid amidrazones,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)N(*)N(*)* +727,Nitriles,"[#1,#6&!$([CX3]=[OX1,SX1])][CX2]#[NX1]",*C#N +728,Acyl fluorides,"[#1,#6][CX3](=[OX1])F",*C(=O)F +729,Acyl chlorides,"[#1,#6][CX3](=[OX1])Cl",*C(=O)Cl +730,Acyl bromides,"[#1,#6][CX3](=[OX1])Br",*C(=O)Br +731,Acyl iodides,"[#1,#6][CX3](=[OX1])I",*C(=O)I +732,Acyl cyanides,"[#1,#6][CX3](=[OX1])[CX2]#[NX1]",*C(=O)C#N +733,Imido esters,"[#1,#6][CX3](=[NX2][#1,#6])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*N=C(*)OC +734,Thiocarboxylic acid derivatives,"[$([#1,#6][CX3](=[SX1])[!#1!#6]),$([#1,#6][CX3](=[OX1])[SX2])]",* +735,Thiocarboxylic acids,"[$([#1,#6][CX3](=[SX1])[OH1,SH1]),$([#1,#6][CX3](=[OX1])[SH1])]",* +736,Thiocarboxylic acid esters,"[$([#1,#6][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#1,#6][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +737,Thiolactones,"[$([#6R][CX3R](=[SX1])[OX2R,SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])]),$([#6R][CX3R](=[OX1])[SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])])]",* +738,Thiocarboxylic acid amides,"[#1,#6][CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=S)N(*)* +739,Thiolactams,"[#6R][CX3R](=[SX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=S +740,Imidothioesters,"[#1,#6][CX3](=[NX2][#1,#6])[SX2][C&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)SC +741,Oxohetarenes,"[$(c(=[OX1])[$(n[#1,#6]),o,s]),$(c(=[OX1])a[$(n[#1,#6]),o,s]),$(c(=[OX1])aa[$(n[#1,#6]),o,s]),$(c(=[OX1])aaa[$(n[#1,#6]),o,s])]",* +742,Thioxohetarenes,"[$(c(=[SX1])[$(n[#1,#6]),o,s]),$(c(=[SX1])a[$(n[#1,#6]),o,s]),$(c(=[SX1])aa[$(n[#1,#6]),o,s]),$(c(=[SX1])aaa[$(n[#1,#6]),o,s])]",* +743,Iminohetarenes,"[$(c(=N)[$(n[#1,#6]),o,s]),$(c(=N)a[$(n[#1,#6]),o,s]),$(c(=N)aa[$(n[#1,#6]),o,s]),$(c(=N)aaa[$(n[#1,#6]),o,s])]",* +744,Orthocarboxylic acid derivatives,"[CX4&!$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]))]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])([!#1!#6])([!#1!#6])[!#1!#6]",*C(*)(*)* +745,Carboxylic acid orthoesters,"[#1,#6][CX4]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*C(OC)(OC)OC +746,Carboxylic acid amide acetals,"[CH1,$([CX4][#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[NX3]([#1,*])[#1,*]",*N(*)*(OC)OC +747,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O +748,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O +749,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O +750,CO2 derivative (general),"[$([Cv4X4]([!#1!#6])([!#1!#6])([!#1!#6])[!#1!#6]),$([CX3](=[!#1!#6])([!#1!#6])[!#1!#6]),$([CX2](=[!#1!#6])=[!#1!#6]),$([CX2](#[!#1!#6])[!#1!#6])]",* +751,Carbonic acid derivatives,"[$([CX3](=[OX1])([!#1!#6])[!#1!#6])&!$([CX3](=[OX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +752,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH] +753,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC +754,Carbonic acid ester halides,"[#6][OX2][CX3](=[OX1])[F,Cl,Br,I]",*C(=O)OC +755,Thiocarbonic acid derivatives,"[$([CX3](=[SX1])([!#1!#6])[!#1!#6])&!$([CX3](=[SX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5]),$([CX3](=[OX1])([!#1!#6])[SX2])&!$([CX3](=[OX1])([#7,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +756,Thiocarbonic acid monoesters,"[$([OH1,SH1][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([OH1][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([SH1][CX3](=[SX1,OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +757,Thiocarbonic acid diesters,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +758,Thiocarbonic acid ester halides,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[F,Cl,Br,I]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[F,Cl,Br,I])]",* +759,Carbamic acid derivatives,"[NX3]([#1,*])([#1,*])[CX3](=[OX1])[!#1!#6!#16!$([Pv5])]",*C(=O)N(*)* +760,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH] +761,Carbamic acid esters (urethanes),"[#6][OX2][CX3](=[OX1])[NH2,NH1,NX3]",*C(=O)OC +762,Carbamic acid halides,"[F,Cl,Br,I][CX3](=[OX1])[NX3]",*C(N)=O +763,Thiocarbamic acid derivatives,"[$([NX3&!$([NX3]([CX3]=[SX1])[CX3]=[OX1,SX1,NX2])][CX3](=[SX1])[!#1!#6!#7!$([Pv5])]),$([NX3&!$([NX3]([CX3]=[OX1])[CX3]=[OX1,SX1,NX2])][CX3](=[OX1])[SH1,SX2])]",* +764,Thiocarbamic acids,"[$([OH1,SH1][CX3](=[SX1])[NX3]),$([SH1][CX3](=[OX1])[NX3])]",* +765,Thiocarbamic acid esters,"[$([#6][OX2,SX2][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])]),$([#6][SX2][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])])]",* +766,Thiocarbamic acid halides,"[F,Cl,Br,I][CX3](=[SX1])[NX3]",*C(N)=S +767,Isoureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([OX2])=[NX2][#1,#6]",*N=C(O)N(*)* +768,Isothioureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([S&!$([SX2]([CX3]=N)C=C)])=[NX2][#1,#6]",*N=C(S)N(*)* +769,Guanidines,"N[CX3](=[NX2][#1,#6])N",*N=C(N)N +770,Semicarbazides,"[$([NX3][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[OX1])[NX3]N=C)]",* +771,Thiosemicarbazides,"[$([NX3][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[SX1])[NX3]N=C)]",* +772,Isonitriles,"[#6&!$([CX3]=[OX1,SX1])][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +773,Sulfuric acid derivatives,[!#1!#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(*)(=O)=O +774,Sulfuric acid,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])[OX2,O-]",*S(*)(=O)=O +775,Sulfuric acid monoesters,"[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(=O)(=O)OC +776,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC +777,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O +778,Sulfuric acid amides,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])N",*S(N)(=O)=O +779,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O +780,Sulfuryl halides,"[!#1!#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +781,Sulfonic acid derivatives,[#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(C)(=O)=O +782,Sulfonic acids,"[#6][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(C)(=O)=O +783,Sulfonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +784,Sulfones,"[#6][Sv6X4](=[OX1,SX1,NX2])(=[OX1,SX1,NX2])[#6]",*=S(=*)(C)C +785,Sulfinic acid derivatives,[#6][Sv4X3](=[OX1])[!#1!#6],*S(C)=O +786,Sulfinic acids,"[#6][Sv4X3](=[OX1])[OH1,O-]",*S(C)=O +787,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O +788,Sulfinic acid halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +789,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O +790,Sulfenic acid derivatives,[#6][Sv2X2][!#6!#1!S],*SC +791,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH] +792,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC +793,Sulfenic acid halides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][F,Cl,Br,I]",*SC +794,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C +795,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH] +796,Thiophenols,c[Sv2H1],c[SH] +797,Phosphoric acid derivatives,"[OX1]=[Pv5X4]([H,!#6!$([SX2])])([H,!#6!$([SX2])])[H,!#6!$([SX2])]",*P(*)(*)=O +798,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH] +799,Phosphoric acid esters,[OX1]=[Pv5X4]([OX2][#6])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(=O)OC +800,Phosphoric acid halides,"[OX1]=[Pv5X4]([F,Cl,Br,I])([!#6!$([SX2])])[!#6!$([SX2])]",*P(*)(*)=O +801,Phosphoric acid amides,[OX1]=[Pv5X4]([NX3])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(N)=O +802,Thiophosphoric acid derivatives,"[$([SX1]=[Pv5X4]([H,!#6])([H,!#6])[H,!#6]),$([OX1]=[Pv5X4]([SX2])([H,!#6])[H,!#6])]",* +803,Thiophosphoric acids,"[$([SX1]=[Pv5X4]([OH1,SH1])([O,S])[O,S]),$([OX1]=[Pv5X4]([SH1])([O,S])[O,S])]",* +804,Thiophosphoric acid esters,"[$([SX1]=[Pv5X4]([OX2,SX2][#6])([!#6])[!#6]),$([OX1]=[Pv5X4]([SX2][#6])([!#6])[!#6])]",* +805,Thiophosphoric acid halides,"[$([SX1]=[Pv5X4]([F,Cl,Br,I])([!#6])[!#6]),$([OX1]=[Pv5X4]([F,Cl,Br,I])([SX2,SH1])[!#6])]",* +806,Thiophosphoric acid amides,"[$([SX1]=[Pv5X4]([NX3])([!#6])[!#6]),$([OX1]=[Pv5X4]([NX3])([SX2,SH1])[!#6])]",* +807,Phosphonic acid derivatives,[OX1]=[Pv5X4]([#6])([!#6])[!#6],*P(*)(C)=O +808,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH] +809,Phosphonic acid esters,[OX1]=[Pv5X4]([#6])([OX2][#6])[!#6],*P(C)(=O)OC +810,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C +811,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O +812,Boronic acid derivatives,[Bv3X3]([#6])([!#6])[!#6],*B(*)C +813,Boronic acids,"[BX3]([#6])([OH1,SH1])[O,S]",*B(*)C +814,Boronic acid esters,"[BX3]([#6])([OX2][#6])[H,!#6]",*B(C)OC +815,Aromatic compounds,[a!r0],* +816,Heterocyclic compounds,[*R]~[*R&!#6]~[*R],*~*~* +817,Aromatic heterocyclic compounds,[a!#6!r0],* +818,α-Aminoacids,"[OH1][CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([#6])[#6])&!$([NH1](CC(=O)[OH1])[CX3]=[OX1,SX1])]",*C(*)(*)C(=O)[OH] +819,α-Hydroxyacids,"[OH1][CX3](=[OX1])[CX4]([OH1])[#1,#6]",*C([OH])C(=O)[OH] +820,"1,2-Diamines","[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])[CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CCN(*)* +821,"1,2-Dithiols","[CX4]([SH1])([#1,#6])([#1,#6])[CX4]([SH1])([#1,#6])([#1,#6])",*C(*)([SH])C(*)(*)[SH] +822,"1,2-Aminothiols","[SH1][CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CC[SH] +823,α-Oxoacids,"[OH1][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(=O)[OH] +824,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH] +825,Dithiophenols,"[$(c([SH1])c([SH1])),$(c([SH1])[aR1]c([SH1])),$(c1([SH1])aac([SH1])aa1)]",* +826,Aminothiophenols,"[$(c([SH1])c[NX3]([#1,#6])[#1,#6]),$(c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]),$(c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1)]",* +827,Aryl halides,"a[F,Cl,Br,I]",** +828,Primary amines,"[NX3H2][c,CX4&!$([CX4]([NH2])[O,N,S,P])]",*[NH2] +829,Secondary amines,"[NX3H1]([c,CX4&!$([CX4]([NX3H1])[O,S,N,P])])[c,CX4&!$([CX4]([NX3H1])[O,S,N,P])]",*[NH]* +830,Tertiary amines,"[NX3]([c,CX4&!$([CX4]([NX3])[O,S,N,P])])([c,CX4&!$([CX4]([NX3])[O,S,N,P])])[c,CX4&!$([CX4]([NX3])[O,S,N,P])]",*N(*)* +831,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C +832,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C +833,Alkynyl halides,"[F,Cl,Br,I][CX2]#[CX2]",*C#C +834,Benzyl halides,"a[CX4][F,Cl,Br,I]",*C* +835,Benzyl fluorides,a[CX4]F,*CF +836,Benzyl chlorides,a[CX4]Cl,*CCl +837,Benzyl bromides,a[CX4]Br,*CBr +838,Benzyl iodides,a[CX4]I,*CI +839,Alkali metals,"[#3,#11,#19,#37,#55,#87]",* +840,Alkaline earth metals,"[#4,#12,#20,#38,#56,#88]",* +841,Transition metals,"[#21,#22,#23,#24,#25,#26,#27,#28,#29,#30,#39,#40,#41,#42,#43,#44,#45,#46,#47,#48,#72,#73,#74,#75,#76,#77,#78,#79,#80,#104,#105,#106,#107,#108,#109,#110,#111,#112]",* +842,Lanthanoids,"[#57,#58,#59,#60,#61,#62,#63,#64,#65,#66,#67,#68,#69,#70,#71]",* +843,Actinoids,"[#89,#90,#91,#92,#93,#94,#95,#96,#97,#98,#99,#100,#101,#102,#103]",* +844,Post-transition metals,"[#13,#31,#49,#50,#81,#82,#83,#113,#114,#115,#116]",* +845,Metalloids,"[#5,#14,#32,#33,#51,#52,#84]",* +846,Nonmetals,"[#1,#6,#7,#8,#15,#16,#34,#9,#17,#35,#53,#85,#117,#2,#10,#18,#36,#54,#86,#118]",* +847,Halogens,"[#9,#17,#35,#53,#85,#117]",* +848,Noble gases,"[#2,#10,#18,#36,#54,#86,#118]",* +849,Chalcogens (oxygen group),"[#8,#16,#34,#52,#84,#116]",* +850,Pnictogens (nitrogen group),"[#7,#15,#33,#51,#83]",* +851,Tetragens (carbon group),"[#6,#14,#32,#50,#8,#114]",* +852,Thioenolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([SX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]",*C(*)=C(*)SC +853,Thioenols,"[CX3]([#1,#6])([#1,#6])=[CX3]([SH1])[#1,#6]",*C(*)=C(*)[SH] +854,Enethiodiols,"[CX3]([#1,#6])([SH1])=[CX3]([#1,#6])([SH1])",*C([SH])=C(*)[SH] +855,Alkynyl alcohols,[CX2]#[CX2][OH1],C#C[OH] +856,Alkynyl thiols,[CX2]#[CX2][SH1],C#C[SH] +857,Thioquinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[SX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1,SX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]",* +858,4halo_pyrimidine_2_6EWG,"n1c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[n;R1]c([F,Cl,Br,I])cc1([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])",*c1cc(*)nc(*)n1 +859,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O,NC(COP(O)(O)=O)C(O)=O +860,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O,CC(OP(O)(O)=O)C(N)C(O)=O +861,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O +862,sulphonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O +863,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S,O=C(S)C(F)(F)F +864,2halo_pyrazine_5EWG,"[n;R1]1c([F,Cl,Br,I])[c;!$(c-N)]nc([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])[c;!$(c-N)]1",*c1cnc(*)cn1 +865,activated_4mem_ring,"[#6]1~[$(C(=O)),$(S(=O))]~[O,S,N]~[$(C(=O)),$(S(=O))]1",*1~*~C*~1 +866,halo_5heterocycle_bis_EWG,"[n,o,s]1c([$(S(=O)(=O)),$([F,Cl]),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])c([$(S(=O)(=O)),$([F,Cl]),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C(=O))])nc1([Cl,Br,I])",*c1*c(*)c(*)n1 +867,hydroxamate_warhead,C([N;H1]([O;D1]))=O,ONC=O +868,thiol_warhead,NC(C[S;D1])C(O)=O,NC(CS)C(O)=O +869,activated_vinyl_sulfonate,"O(-S(=O)(=O))C=[$(C(S(=O)(=O))),$(C(C(F)(F)(F))),$(C(C#N)),$(C(N(=O)(=O))),$(C([N+](=O)[O-])),$(C(C(=O)));!$(C(N))]",*=CO[SH](=O)=O +870,acyl_cyanide,C(=O)-C#N,N#CC=O +871,pentafluorophenylester,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +872,vinyl_carbonyl_EWG,"[C;!R]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])=[C;!R]([C;!R](=O))([!$([#8]);!$([#7])])",*C(*)=C(*)C=O +873,4halo_pyrimidine_5EWG,"n1c[n;R1]c([F,Cl,Br,I])[#6]([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])c1",*C1cncnc1* +874,alpha_halo_EWG,"[$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-])]-[CH,CH2]-[Cl,Br,I,$(O(S(=O)(=O)))]",*** +875,2halo_pyrazine_3EWG,"[n;R1]1c([F,Cl,Br,I])c([$(S(=O)(=O)),$(C(F)(F)(F)),$(C#N),$(N(=O)(=O)),$([N+](=O)[O-]),$(C=O)])ncc1",*c1nccnc1* +876,boron_warhead,"[C,c]~[#5]",*~B +877,diamino_sulfide,"[N,n]~[S;!R;D2]~[N,n]",*~S~* +878,dicarbonyl_sulfonamide,"[$(N(-C(=O))(-C(=O))(-S(=O))),$(n([#6](=O))([#6](=O))([#16](=O)))]",* +879,acyl_imidazole,"[C;!$(C-N)](=O)n1[c;H1,$([#6]([*;!R]))]n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1ccnc1 +880,halo_phenolic_sulfonyl,"S(=O)Oc1c([Cl,F])[cH1,$(c[F,Cl])]c([F,Cl])[cH1,$(c[F,Cl])]c1([F,Cl])",*c1*c(*)c(OS=O)c(*)*1 +881,oxaziridine,"C1~[O,S]~N1",*1~CN~1 +882,sulf_D3_nitrogen,"[S;D3](-N)(-[c,C])(-[c,C])",*[SH](*)N 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+1041,Anil_di_alk_A,"[CH2,CH3]N([CH2,CH3])c1cc([H,CH2,CH3,$(O(c)[CH2][CH2,CH3])])c(-[#7])[cH]c1",*c1cc(N(*)*)c[cH]c1N +1042,Anil_di_alk_B,c1c(ccc(c1)[#6]=[#6])[#7]([CX4])[CX4],CN(C)c1ccc(C=C)cc1 +1043,Pyrrole_A,"[#7]1(c2acccc2)-,:[#6]([CX4])=,:[#6]-,:[#6!H0]=,:[#6]1[CX4]",CC1=CC=C(C)N1c1*cccc1 +1044,Pyrrole_B,"[#7]1(c2acccc2)-,:[#6]([CX4])=,:[#6]-,:[#6H]=,:[#6]1cc",CC1=C[CH]=C(cc)N1c1*cccc1 +1045,Catechol_A,c1ccc(c(c1)[OH1])[OH1],[OH]c1ccccc1[OH] +1046,Ene_five_one_A,c2ccc1C(=[OX1])C(=C)C(=[OX1])c1c2,C=C1C(=O)c2ccccc2C1=O +1047,Ene_five_one_B,"[cH]1[cH][cH][cH]c2[CH2]C(=[OX1])C(=C([CH2,CH3])[CH2,CH3])c12",*C(*)=C1C(=O)[CH2]c2[cH][cH][cH][cH]c21 +1048,Ene_five_het_B,C1(=C)C(N=CS1)=O,C=C1SC=NC1=O +1049,Ene_five_het_C,C1(C(C=C[!#1!#6]1)=C)=[!#1!#6],*=C1*C=CC1=C +1050,Ene_five_het_D,C1(=C)C(=[OX1])NNC1=[OX1],C=C1C(=O)NNC1=O +1051,Ene_five_het_E,NC=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2,NC=C1*c2ccccc2C1=O +1052,Ene_five_het_F,c1(ccccc1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)S2,O=C1C(=Cc2ccccc2)Sc2ccccc21 +1053,Ene_one_ene_A,C=!@C([!#1])-&@C(=!@[!#1!#6])-&@C(=!@C)[!#1],*C(=C)C(=*)C(*)=C +1054,Ene_one_ester,[#6][#6](=[#8])[#6!H0]=[#6]([#7!H0][#6])[#6](=[#8])[#8][#6],CNC(=CC(C)=O)C(=O)OC +1055,Ene_one_A,a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])Nc2cc3c(cc2)nc(cc3)N([#6])[#6],CN(C)c1ccc2cc(NC(=O)C=C*3:*:*:*:*:*:3)ccc2n1 +1056,Ene_one_D,c([OH1])c-C(=[OX1])[C!H0]=C([#6])[#6],CC(C)=CC(=O)cc[OH] +1057,Ene_one_hal,"[#6][#6]=[#6]([F,Cl,Br,I])[#6](=[OX1])[#6]",*C(=CC)C(C)=O +1058,Ene_cyano_A,[#6](C#[#7])(C#[#7])=Cc1ccccc1,N#CC(=Cc1ccccc1)C#N +1059,Ene_rhod_B,"[#16]1C(=O)NC(=O)C1=[#6!H0][$([#6]Br),$(c[cH]c([F,Cl,Br,I])cc[F,Cl,Br,I]),$(c[cH][cH]cS[CH2,CH3]),$(ccccccccccO[CH2,CH3]),$(c2c([CH2,CH3])n([CH2,CH3])c([CH2,CH3])c2)]",*C=C1SC(=O)NC1=O +1060,Hzone_pipzn,[#6]N1[CH2][CH2]N([CH2][CH2]1)[#7]=[#6!H0]ca,*cC=NN1[CH2][CH2]N(C)[CH2][CH2]1 +1061,Hzone_pyrrol,n1(C)[cH1][cH1][cH1]c1C=NN,Cn1[cH][cH][cH]c1C=NN +1062,Hzone_enamin,"[#7!H0][#7]=[#6][#6]([H,#6])=[#6]([#6])-!@[#7,#8&!H0]",*C(C)=C(*)C=NN +1063,Hzone_anil_di_alk,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6H]=[#7][#7][$([#6](=O)[CH2]Scn),$([#6](=O)[CH2]aan),$([#6](=O)cc[OH1]),$(cn),$([CH2][#6!H0][OH1])])[cH][cH]1",*NN=[CH]c1[cH][cH]c(N(*)*)[cH][cH]1 +1064,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2,C=NNC(=O)c1[cH]c2[cH][cH][cH][cH]c2[cH]c1[OH] +1065,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1,O=C1CC(=O)c2ccccc21 +1066,Keto_keto_beta_zone,"cc[N!H0]N=C([CH2,CH3])[CH2]C([CH2,CH3])=N[N!H0]cc",*C([CH2]C(*)=NNcc)=NNcc +1067,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1],N#CC=C([NH2])C(C#N)C#N +1068,Cyano_pyridone_A,"[#6]1(=[SX1])-,:[#7!H0]-,:*=,:*-,:*=,:[#6]1C#[NX1]",N#CC1=**=*NC1=S +1069,Cyano_pyridone_B,"[#6]1(=,:[#6](-,:[#6](=O)-,:[#7]-,:[#6](=,:[#7]1)[!#1!#6])C#[#7])[#6]",*C1=NC(C)=C(C#N)C(=O)N1 +1070,Cyano_imine_A,[N!H0]N=C(C#[NX1])C=[!#6&!R],*=CC(C#N)=NN +1071,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1,N#CC(C#N)=NNc1ccccc1 +1072,Cyano_cyano_A,"C(C#[NX1])(C#[NX1])C([$(C#[NX1]),$(C=N)])C#[NX1]",*C(C#N)C(C#N)C#N +1073,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9,C1C=CC2C1CNc1ccccc12 +1074,Anil_no_alk,"c1([NH2])[cH][cH]c([#7,#8,CH2,CH3])[cH][cH]1",*c1[cH][cH]c([NH2])[cH][cH]1 +1075,Anil_di_alk_furan_A,"N([CH2,CH3])([CH2,CH3])c1oc(C=N[N!H0]C(=[!#1!#6]))[cH][cH]1",*N(*)c1[cH][cH]c(C=NNC=*)o1 +1076,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7],Nc1c2ccccc2nc2ccccc12 +1077,Thiaz_ene_A,"C1([CH2,CH3,$(cc)])=C([H,CH2,CH3,$(C=O)])SC(N1([H,$([C!H0]),$(cc)]))=[#7!R]",*C1=C(*)N(*)C(=N)S1 +1078,Thiaz_ene_B,"C1([$(NC(=[OX1])cc),NH2])=C(-!@C(=[OX1])N[CH2,CH3])SC(N1[$([CH2][CH]=[CH2]),$(cc)])=[SX1]",*NC(=O)C1=C(*)N(*)C(=S)S1 +1079,Thio_carbonate_A,"[#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]",*c1ccc2c(c1)SC(=*)O2 +1080,Thiophene_amino_Aa,[NH2]c1sc([!#1])c([!#1])c1C=[OX1],*c1sc([NH2])c(C=O)c1* +1081,Thiophene_amino_Ab,"[H,CH2,CH3,$(cc)]c1sc([#7!H0][#6](=O)[#6])c(C(=O)[#8])c1[$(c2ccccc2),$(c3sccc3)]",*c1sc(NC(C)=O)c(C(O)=O)c1* 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+1093,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1 +1094,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1 +1095,Thio_dibenzo,"[SX1]=[#6]1-,:[#6]=,:[#6]-,:[!#1!#6]-,:[#6]=,:[#6]1",S=C1C=C*C=C1 +1096,Het_65_A,"[OX1]=CC1=C2N=C([CH2,CH3])C=C([OH1])N2N=C1",*C1=NC2=C(C=O)C=NN2C([OH])=C1 +1097,Het_6_tetrazine,"N~c1[n,$(c(N))][n,c!H0,$(c[N!H0])]c([N!H0,$([OX2][CH2,CH3])])nn1",*c1*:*c(~N)nn1 +1098,Imidazole_A,"[#7]1-,:[#6](-c2ccccc2)=,:[#6](-c3ccccc3)-,:[#7!H0]-,:[#6]1-ca",*cC1NC(c2ccccc2)=C(c2ccccc2)N1 +1099,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH] +1100,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1101,Anisol_A,"c1(O[CH2,CH3])c([H,CH2,CH3])[cH]c(O[CH2,CH3])c([CH2][$([N!H0]C(=[OX1])[CH2][CH2][CH2,CH3]),$([C!H0]([CH2,CH3])[N!H0]C(=[SX1])[N!H0])])[cH]1",*[CH2]c1[cH]c(O*)c(*)[cH]c1O* +1102,Anisol_B,"[CH2,CH3](c4c([cH][cH]c([cH]4)[CH2][N!H0][CX4])O[CH2,CH3])",*Oc1[cH][cH]c([CH2]NC)[cH]c1* +1103,Anthranil_acid_B,"c3cc(C(=[OX1])[N!H0]c4ccccc4C(=[OX1])[OH1])cc1c3C(=[OX1])N([CH2,CH3])C1=[OX1]",*N1C(=O)c2ccc(C(=O)Nc3ccccc3C(=O)[OH])cc2C1=O +1104,Anthranil_acid_C,"[#6]1(=,:[#6]([NH2])-,:[#7](-c7ccccc7C(=[OX1])[OH1])-,:[#7]=,:[#6]1C=[OX1])[$(C#[NX1]),$(C=S)]",*C1=C([NH2])N(c2ccccc2C(=O)[OH])N=C1C=O +1105,Anthranil_acid_D,"c12ncccc1-,:[#6]([NH2])=,:[#6](C(=[OX1])~[OX1,O-])-,:[#16]2",*~C(=O)C1=C([NH2])c2cccnc2S1 +1106,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH] +1107,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH] +1108,Anthranil_acid_G,"c1([cH][cH]c(O[CH2,CH3])[cH]c1(C(=[OX1])[OH1]))[N!H0]cc",*Oc1[cH][cH]c(Ncc)c(C(=O)[OH])[cH]1 +1109,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1 +1110,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1 +1111,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH] +1112,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1 +1113,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1 +1114,Anil_alk_A,"[CH2,CH3]Occ[CH2][N!H0]c1[cH]c2n[cH]n([#6!H0])c2[cH][cH]1",*Occ[CH2]Nc1[cH][cH]c2c([cH]1)n[cH]n2C +1115,Anil_alk_B,"[N!H0](c1[cH][cH]c([CH2,CH3])[cH][cH]1)[CH2][CH2]c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c([CH2][CH2]Nc2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1116,Anil_alk_C,"[N!H0](c1ccccc1)C([#6])([#6])c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c(C(C)(C)Nc2ccccc2)[cH][cH]1 +1117,Anil_alk_D,"[N!H0](c1[cH][cH]c([C!H0]([CH2,CH3])[CH2,CH3])[cH][cH]1)[CH2][CH2]N([CH2,CH3])[CH2,CH3]",*C(*)c1[cH][cH]c(N[CH2][CH2]N(*)*)[cH][cH]1 +1118,Anil_alk_thio,c1ccc2c(c1)C3=C(C([#6])([#6])N2)SSC3=*,*=C1SSC2=C1c1ccccc1NC2(C)C +1119,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2 +1120,Anil_di_alk_F,"c1c(ccc(N([H,CX4])([H,CX4]))c1)[CX4]c2ccc(cc2)N([H,CX4])([H,CX4])",*N(*)c1ccc(Cc2ccc(N(*)*)cc2)cc1 +1121,Anil_di_alk_J,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6!H0]=[#7][#7]=[#6]([#6])-cc)[cH][cH]1",*N(*)c1[cH][cH]c(C=NN=C(C)cc)[cH][cH]1 +1122,Anil_di_alk_I,"[cH]1c([N!H0]C(=[OX1])c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=O)c2ccccc2)[cH]1 +1123,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1 +1124,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12 +1125,Anil_di_alk_ene_B,"[CH2,CH3]N([CH2,CH3])C1=Cc2ccccc2[CH2]1",*N(*)C1=Cc2ccccc2[CH2]1 +1126,Anil_di_alk_furan_B,"[CH2,CH3]N([CH2,CH3])c1[cH][cH]c(o1)[C!H0]=CC#[NX1]",*N(*)c1[cH][cH]c(C=CC#N)o1 +1127,Anil_di_alk_indol,"c12[cH][cH]c(N([CH2,CH3])[CH2,CH3])[cH]c1-,:[#6](S(=[OX1])=[OX1])=,:[#6H]-,:[#7!H0]2",*N(*)c1[cH][cH]c2c([cH]1)C(S(=O)=O)=[CH]N2 +1128,Anil_no_alk_indol_A,"c12[cH][cH]c([NH2])[cH]c1[cH][cH]n2[CH2,CH3]",*n1[cH][cH]c2[cH]c([NH2])[cH][cH]c21 +1129,Anil_NH_alk_A,"c1([N!H0][CH2,CH3])[cH][cH]c2c([cH]1)[#7!H0]-,:[#6](=[OX1])-,:[#7!H0]2",*Nc1[cH][cH]c2c([cH]1)NC(=O)N2 +1130,Anil_NH_alk_B,[N!H0](c1ccacc1)c2ccc([N!H0][C!H0])cc2,CNc1ccc(Nc2cc*cc2)cc1 +1131,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC +1132,Anil_NH_alk_D,"[NH2]c1c([N!H0][C!H0]([#6])[C!H0][CH2,CH3])c[cH][cH][cH]1",*CC(C)Nc1c[cH][cH][cH]c1[NH2] +1133,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1 +1134,Anil_NH_no_alk_B,"[NH2]c1c([N!H0]S(=[OX1])=[OX1])[cH]c([N!H0][CH2,CH3])c([F,Cl,Br,I])[cH]1",*Nc1[cH]c(NS(=O)=O)c([NH2])[cH]c1* +1135,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1 +1136,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH] +1137,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12 +1138,Anil_OC_alk_A,"[cH]1[cH][cH]c2c([cH]1)c3c(o2)[cH]c([N!H0][CH2,CH3])c(O[CH2,CH3])[cH]3",*Nc1[cH]c2oc3[cH][cH][cH][cH]c3c2[cH]c1O* +1139,Anil_OC_alk_B,"c2ccccc2N1C(=[OX1])C([N!H0]c2ccc(O[CH2,CH3])cc2)=C([F,Cl,Br,I])C1=[OX1]",*Oc1ccc(NC2=C(*)C(=O)N(c3ccccc3)C2=O)cc1 +1140,Anil_OC_alk_C,"[H,CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2]c2nccn2",*Oc1[cH][cH][cH][cH]c1N[CH2]c1nccn1 +1141,Anil_OC_alk_D,"[CH2,CH3]Oc1[cH][cH]c([CH2,CH3])[cH]c1[NH][CH2]c2c([CH2,CH3,$(O[CH2,CH3])])cccc2",*Oc1[cH][cH]c(*)[cH]c1[NH][CH2]c1ccccc1* +1142,Anil_OC_alk_E,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2][C!H0]([OH1])[CH2,CH3]",*Oc1[cH][cH][cH][cH]c1N[CH2]C(*)[OH] +1143,Anil_OC_alk_F,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][C!H0]([#16])C=[OX1]",*Oc1[cH][cH][cH][cH]c1NC(S)C=O +1144,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1 +1145,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2] +1146,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1 +1147,Anil_no_alk_B,"[NH2]c1c(n2cccc2)[cH]c([CH2,CH3])c([CH2,CH3])[cH]1",*c1[cH]c([NH2])c(n2cccc2)[cH]c1* +1148,Anil_no_alk_D,"n1c([NH2])c([CH2,CH3])[cH]c([CH2,CH3])c1[NH2]",*c1[cH]c(*)c([NH2])nc1[NH2] +1149,Anil_no_alk_C,"[NH2]c1[cH][cH]c([cH][cH]1)-c2[cH]c(C=[OX1])c([CH2,CH3])o2",*c1oc(-c2[cH][cH]c([NH2])[cH][cH]2)[cH]c1C=O +1150,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12 +1151,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1 +1152,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12 +1153,Hzone_acyl_misc_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C(=[OX1])[N!H0]N=C([H,CH2,CH3])c2cc(*-*-*c3occc3)ccc2",*C(=NNC(=O)c1[cH][cH]c(*)o1)c1cccc(***c2ccco2)c1 +1154,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1 +1155,Hzone_thiophene_A,"[cH]2[cH][cH][cH]c1c2c([C!H0]=N[N!H0]([$(c3nc[cH]s3),$(c[cH][cH]),$(cncncn),$(cnnnn)]))c([H,$([OH1]),CH2,CH3])[a!c]1",*NN=Cc1c(*)*c2[cH][cH][cH][cH]c12 +1156,Hzone_thiophene_B,"c1(s[cH][cH]c1[H,CH2,CH3])[C!H0]=N[N!H0]c2ccccc2",*c1[cH][cH]sc1C=NNc1ccccc1 +1157,Hzone_phenone,"C(c1[cH]cc([H,CX4])[cH][cH]1)(c2[cH][cH]c([H,Cl])[cH][cH]2)=[$(NO[CH2][CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(NO[CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(N[N!H0]C(=[NH1])[NH2]),$([#6!H0][#7])]",*c1c[cH]c(C(=*)c2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1158,Hzone_furan_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[N!H0]c2nccs2",*C(=NNc1nccs1)c1[cH][cH]c(*)o1 +1159,Hzone_furan_B,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[NH]c2ccncc2",*C(=N[NH]c1ccncc1)c1[cH][cH]c(*)o1 +1160,Hzone_furan_C,c1ccccc1N(c2ccccc2)N=[C!H0]c3ac([cH][cH]3)-c4cc(C(=[OX1])[OH1])ccc4,O=C([OH])c1cccc(-c2*c(C=NN(c3ccccc3)c3ccccc3)[cH][cH]2)c1 +1161,Hzone_furan_E,[OH1]C(=[OX1])c1cc(ccc1)-cacC=N[N!H0]C(=[OX1])[CH2][#8],O[CH2]C(=O)NN=Cc*c-c1cccc(C(=O)[OH])c1 +1162,Hzone_naphth_A,"[cH]1[cH][cH]c2[cH][cH]c(C=N[N!H0][$(cc),$(C=[SX1])])[cH]c2c1",*NN=Cc1[cH][cH]c2[cH][cH][cH]cc2[cH]1 +1163,Hzone_acid_A,"[cH]1[cH]c(O[CH2,CH3])[cH]c2C(=N[N!H0]c4[cH][cH]c(C(=[OX1])[OH1])[cH][cH]4)c3[cH]c(O[CH2,CH3])[cH][cH]c3c12",*Oc1[cH][cH]c2c([cH]1)C(=NNc1[cH][cH]c(C(=O)[OH])[cH][cH]1)c1[cH]c(O*)[cH][cH]c12 +1164,Hzone_acid_D,[OH1]C(=[OX1])c1ccc(cc1)NN=[C!H0]c2ac([cH][cH]2)-c3ccccc3,O=C([OH])c1ccc(NN=Cc2*c(-c3ccccc3)[cH][cH]2)cc1 +1165,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1 +1166,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1 +1167,Het_5_C,"N1=C(c2ccccc2)[CH2]C([OH1])([CX4](F)(F)F)N1[$(cccccc),$(C(=S)cccccc)]",*N1N=C(c2ccccc2)[CH2]C1([OH])C(F)(F)F +1168,Het_5_D,"N1(c2ccccc2)N=C([CH2,CH3])[C!H0](S[#6])C1=[OX1]",*C1=NN(c2ccccc2)C(=O)C1SC +1169,Het_5_E,"N1(c2cccc3ccccc23)N=C([CH2,CH3])[CH2]C1=[OX1]",*C1=NN(c2cccc3ccccc23)C(=O)[CH2]1 +1170,Het_5_ene,"C1(=[OX1])C(=C([CH2,CH3])[N!H0][CH2][CH2][CH2,CH3])N=C(c2ccccc2)O1",*[CH2][CH2]NC(*)=C1N=C(c2ccccc2)OC1=O +1171,Het_5_inium,"[#7]1(c2ccccc2)[#6!H0]=[#7+,#7v4](c3ccccc3)[#6](=Nc4ccccc4)N1",C1=*(c2ccccc2)C(=Nc2ccccc2)NN1c1ccccc1 +1172,Het_5_pyrazole_OH,"n1(c2[cH][cH][cH][cH][cH]2)nc([CX4])c([H,C!H0])c1[OH1]",*c1c(C)nn(c2[cH][cH][cH][cH][cH]2)c1[OH] +1173,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1 +1174,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1 +1175,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1 +1176,Het_6_pyridone_NH2,[OH1]c2nc([NH2])acc2[CH2]C(=[OX1])[#8],[NH2]c1*cc([CH2]C(O)=O)c([OH])n1 +1177,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1 +1178,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2 +1179,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1 +1180,Het_65_B,a1a3a(aaa1)[N!H0]N(C3=O)[#6],CN1N*2:*:*:*:*:*:2C1=O +1181,Het_65_C,"C1=CC=CC2=NC([$(C([!#1])=[C!H0]cc),$(coc)])=C(Ncc)N12",*C1=C(Ncc)N2C=CC=CC2=N1 +1182,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1183,Het_65_F,"[#16]1-,:[#6]2:[#6](-,:[#6]([CH2,CH3])=,:[#6]1[CH2,CH3])c(ncn2)NN=C[#6]3=,:[#6]-,:[#6]=,:[#6]-,:[#8]3",*C1=C(*)C2:C(ncnc2NN=CC2=CC=CO2)S1 +1184,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1 +1185,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1 +1186,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12 +1187,Het_65_J,"o1c([#6](~[#8])~[#8])cc2[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c12",*Oc1[cH]c2cc(C(~O)~O)oc2[cH]c1O* +1188,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1 +1189,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O +1190,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12 +1191,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21 +1192,Het_65_pyridone_A,"c1([CH2][CH2,CH3])c([CH2,CH3])c2C(=[!#1!#6X1])N([C!H0][$(C(=O)O),$(cc)])C([H,$(S(C)[CH2,CH3])])=Nc2[a&!c;X2]1",*CN1C(=*)c2c(*c([CH2]*)c2*)N=C1* +1193,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1 +1194,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1 +1195,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1 +1196,Het_66_B,"c1ccc4c(c1)nc(nc4)[N!H0]C2=NC(C=C[N!H0]2)([CH2,CH3])[CH2,CH3]",*C1(*)C=CNC(Nc2ncc3ccccc3n2)=N1 +1197,Het_66_C,c1ccc2nc([C!H0]=C([OH1])[#6])c([C!H0]=C([OH1])[#6])nc2a1,CC([OH])=Cc1nc2*cccc2nc1C=C(C)[OH] +1198,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc +1199,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1 +1200,Het_66_anisole,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0]c2c3c(O[CH2,CH3])ccc(O[CH2,CH3])c3ncc2",*Oc1[cH][cH][cH][cH]c1Nc1ccnc2c(O*)ccc(O*)c12 +1201,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1 +1202,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3 +1203,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21 +1204,Het_565_indole,"[#6!H0]1=,:[#6!H0]-,:[#7]([CH2,CH3])c7c1c9[#6!H0]=,:[#6!H0]-,:[#7](c9c(c7O[CH2,CH3])O[CH2,CH3])[CH2,CH3]",*Oc1c(O*)c2c(c3c1N(*)C=C3)C=CN2* +1205,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21 +1206,Het_666_B,"c1cccc9c1Oc2c(N9[CH2][CH2,CH3])cccc2",*[CH2]N1c2ccccc2Oc2ccccc21 +1207,Het_666_C,"c13cc2ccccc2cc1-,:[#7]([CH2,CH3])-,:[#6](=[OX1])-,:[#6](-cc[N!H0][CH2,CH3])=,:[#7]3",*NccC1=Nc2cc3ccccc3cc2N(*)C1=O +1208,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12 +1209,Het_pyridiniums_B,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:*2=,:[#6]1-,:*=,:[#7+,#7v4](~cc)-,:*=,:[#6]2[H,*]",*C1=**(~cc)=*C2=*1C=CC=C2 +1210,Het_pyridiniums_C,"[#6]1~[#6]~[#6]~[#7+,#7v4]2~[#6](~[#7]1)~[#6]3~[#6]~[#6]~[#6]~[#7](-cc)~[#6]3~[#7]2",ccN1~C~C~C~C2C~1~N*1~C~C~CN~C~1~2 +1211,Het_thio_5_A,"[CH2,CH3][SX2]c1n(-!@[CH2,CH3])c(-c2ccccc2)[cH]n1",*Sc1n[cH]c(-c2ccccc2)n1* +1212,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1 +1213,Het_thio_5_C,"[SX1]=[#6]1-,:[#7!H0]-,:[#7]=,:[#6](c2[cH][cH]c(O[CH2,CH3])[cH][cH]2)-,:[#8]1",*Oc1[cH][cH]c(C2=NNC(=S)O2)[cH][cH]1 +1214,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1 +1215,Het_thio_5_imine_B,"N1([CH2,CH3])C(=S)N(-cc)C(=N-cc)C1=N-cc",*N1C(=S)N(cc)C(=Ncc)C1=Ncc +1216,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc +1217,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1 +1218,Het_thio_6_furan,"[CH2,CH3][SX2]c1nc(-c2o[cH][cH][cH]2)c(-c3o[cH][cH][cH]3)nn1",*Sc1nnc(-c2[cH][cH][cH]o2)c(-c2[cH][cH][cH]o2)n1 +1219,Het_thio_65_A,"[#7]1=,:[#6]([SX2][CH2,CH3])-,:[#7]=,:[#7]-,:[#6]2=,:[#6]1-,:[#6]([CH2,CH3])=,:[#7]-,:[#7]2-c3cccccc3",*SC1=NC2=C(N=N1)N(c1cccccc1)N=C2* +1220,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1 +1221,Het_thio_65_C,"n1c2ccccc2n([CH2,CH3])c1S[CH2]C(=[OX1])[N!H0]N=[C!H0][C!H0]=[C!H0]",*n1c(S[CH2]C(=O)NN=CC=C)nc2ccccc21 +1222,Het_thio_65_D,"c1(S[CH2]C(=[OX1])[NH]-cc)nc2[cH]c([F,Cl,Br,I])c[cH]c2[nH]1",*c1c[cH]c2[nH]c(S[CH2]C(=O)[NH]cc)nc2[cH]1 +1223,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1 +1224,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1 +1225,Het_thio_67_A,"[CH2,CH3][SX2]c1nc2OC=Ncc-c2nn1",*Sc1nnc2c(n1)OC=Ncc-2 +1226,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21 +1227,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12 +1228,Het_thio_656c,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]2-,:[#7+,#7v4]=,:[#6]3-,:[#7](N=C(c5ccccc5)[CX4]S3)-,:[#6]12",*1=C2SCC(c3ccccc3)=NN2C2C=CC=CC12 +1229,Het_thio_665,"c1ccc7c(c1)NC3=C(S7)SC(=C3)[CH2,CH3]",*C1=CC2=C(S1)Sc1ccccc1N2 +1230,Het_thio_666_A,"[cH]1[cH][cH][cH]c5N([H,CH3,$([CH2][C!H0])])c7c(~[H,$([N!H0][CX4]),$(cc)])c(~[H,$(cc)])c([H,NH2,$([OX2][CX4])])[cH]c7Sc15",*~c1c(~*)c2c([cH]c1*)Sc1[cH][cH][cH][cH]c1N2* +1231,Het_thio_676_A,"c1ccc4c(c1)Sc8[cH][cH]c([cH]c8C(C4)N([H,CX4])([H,CX4]))[H,#8,#16X2,CX4,$(N([H,CX4])[H,CX4])]",*c1[cH][cH]c2c([cH]1)C(N(*)*)Cc1ccccc1S2 +1232,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21 +1233,Het_thio_pyr_A,"n1c(S[C!H0])c(C#[NX1])c(c2ccc(O[Ch2,CH3])cc2)[cH]c1(cc)",*Oc1ccc(c2[cH]c(cc)nc(SC)c2C#N)cc1 +1234,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1 +1235,Het_thio_N_5B,"[#6]1~[#6](~[#7]~[#7]~[#6](~[CH2,CH3])~[CH2,CH3])~[#7]~[#16]~[#6]1",*~C(~*)~N~N~C1~CC~S~N~1 +1236,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1 +1237,Het_thio_N_55,[C!H0]c1nn(c3ccccc3)s2[a!c]acc12,Cc1nn(c2ccccc2)s2*:*cc12 +1238,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2 +1239,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc +1240,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1 +1241,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21 +1242,Styrene_B,"c1ccc4c(c1)[SX2,CX4]c8ccc(cc8C4=CC)[H,Cl,CX4]",*c1ccc2c(c1)C(=CC)c1ccccc1*2 +1243,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2 +1244,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21 +1245,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc +1246,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21 +1247,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN +1248,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S +1249,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N +1250,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1 +1251,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1 +1252,Ene_five_het_G,"C1(=[OX1])C(=[C!H0][$(c2ccccc2),$(c2ccc[a!c]2)])N=C(aaa)[#16,$(Naa)]1",*C=C1N=C(*:*:*)*C1=O +1253,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S +1254,Ene_five_het_I,c1(ccco1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2,O=C1C(=Cc2ccco2)*c2ccccc21 +1255,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S +1256,Ene_five_het_K,"[#7]1([#6])-,:[#6H]=,:[#6H]-,:[#6H]=,:[#6]1([CH]=C2C(=[OX1])[!#6]C=,:*2)",CN1[CH]=[CH][CH]=C1[CH]=C1*=C*C1=O +1257,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1 +1258,Ene_five_het_M,"C1=,:C[O,S]C(=CC=[OX1])C1=[OX1]",O=CC=C1*C=CC1=O +1259,Ene_five_het_N,"C1(=[OX1])C(=[C!H0]c2cc([F,Cl,Br,I])ccc2O[CH2,CH3])N=C(S[CH2,CH3])S1",*Oc1ccc(*)cc1C=C1N=C(S*)SC1=O +1260,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1 +1261,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O +1262,Ene_six_het_D,[OX1]=C1NNC(aa)=NC1=[C!H0],*:*C1=NC(=C)C(=O)NN1 +1263,Ene_quin_methide,"aaC([H,$(C#[NX1])])=[#6]1-,:[#6]=,:[#6]-,:[#6](=[OX1,N!R])-,:[#6]=,:[#6]1",*C(*:*)=C1C=CC(=*)C=C1 +1264,Ene_rhod_C,"S1C(=Ncc)N([H,$([CH2][CH2]O),$(cc)])C(=[OX1])C1(=[C!H0][$(cccCl),$(c[a!c])])",*C=C1SC(=Ncc)N(*)C1=O +1265,Ene_rhod_D,"S1C(=!@N[H,$([N!H0](N)cc)])N([H,$(cnccs)])C(=[OX1])C1=[C!H0]cc[Cl,$(O[C!H0])]",*ccC=C1SC(=N*)N(*)C1=O +1266,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S +1267,Ene_rhod_F,"n1ccc([C!H0]=C2C(=[OX1])NC(=[!#1!#6])N2)c1[CH2,CH3]",*c1nccc1C=C1NC(=*)NC1=O +1268,Ene_rhod_G,[OH1][CX3](=[OX1])c1cccc(c1)cac[C!H0]=C2C(=[!#1!#6])NC(=[!#1!#6])[!#1!#6]2,*=C1*C(=Cc*cc2cccc(C(=O)[OH])c2)C(=*)N1 +1269,Ene_rhod_H,"N1=C([CH2,CH3])C(=[OX1])N=C2N1C(=[OX1])C(=[C!H0]cc)S2",*C1=NN2C(=O)C(=Ccc)SC2=NC1=O +1270,Ene_rhod_I,"N1([CH2,CH3])C(=S)[N!H0]C(=[C!H0]c2cc(Br)ccc2)C1(=O)",*N1C(=O)C(=Cc2cccc(Br)c2)NC1=S +1271,Ene_rhod_J,"[CH2,CH3]N1C(=[#16,#7])[!#6]C(=[#6]2-,:[#6H]=,:[#6H]cc-,:[#7]2[CH2,CH3])C1=[OX1]",*N1cc[CH]=[CH]C1=C1*C(=*)N(*)C1=O +1272,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1 +1273,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O +1274,Ene_misc_C,"c1ccc4c(c1)N(C(C=C4)([CH2,CH3])[CH2,CH3])C(=[OX1])[N!H0]c3ccc(c(c3)O[CH2,CH3])O[CH2,CH3]",*Oc1ccc(NC(=O)N2c3ccccc3C=CC2(*)*)cc1O* +1275,Ene_misc_D,"c12[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c1C([#6])=C([#6])S[CH2]2",*Oc1[cH]c2c([cH]c1O*)C(C)=C(C)S[CH2]2 +1276,Ene_misc_E,"c1(O[CH2,CH3])c(O[CH2,CH3])[cH]c2C=C[C!H0]Sc2[cH]1",*Oc1[cH]c2c([cH]c1O*)SCC=C2 +1277,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1 +1278,Dhp_amino_CN_A,"[NH2]C1=C(C#[NX1])[C!H0](cc)C([CH2,CH3])=C(C=C)O1",*C1=C(C=C)OC([NH2])=C(C#N)C1cc +1279,Dhp_amino_CN_B,"[NX3H2,OX2H1]C1=C(C#[NX1])[C!H0](cc)c2c(n(C)nc2)O1",*C1=C(C#N)C(cc)c2cnn(C)c2O1 +1280,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N +1281,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21 +1282,Dhp_amino_CN_E,"[CH2,CH3][SX2]C1=C(C#[NX1])[C!H0](cc)C(C#[NX1])C(=O)N1",*SC1=C(C#N)C(cc)C(C#N)C(=O)N1 +1283,Dhp_amino_CN_F,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](c2cccs2)-,:[#6](C(=[OX1])O[#6])=,:[#6]([CH2,CH3])-,:[#8]1",*C1=C(C(=O)OC)C(c2cccs2)C(C#N)=C([NH2])O1 +1284,Dhp_amino_CN_G,"[SX2]1C=C(C#[NX1])C([#6])(C=[OX1])C([$(C=[OX1]),$(C#[NX1])])=C1[NH2]",*C1=C([NH2])SC=C(C#N)C1(C)C=O +1285,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N +1286,Dhp_keto_A,"[#7]1([H,CX4])-,:[#6]=,:[#6](C(=[OX1])ccc)-,:[#6]([#6])-,:[#6]([$(C=[OX1]),$(C#[NX1])])=,:[#6]1[CH3]",*C1=C([CH3])N(*)C=C(C(=O)ccc)C1C +1287,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2] +1288,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1 +1289,Сyano_keto_A,"[CH2,CH3][C!H0](C#[NX1])C(=[OX1])[#6]",*C(C#N)C(C)=O +1290,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N +1291,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N +1292,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc +1293,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O +1294,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O +1295,Cyano_pyridone_C,"C1(C([CH2,CH3])=C(C#[NX1])C(~[#8])~[#7]~[#6]1(~[#8]))=[C!H0]cc",*C1=C(C#N)C(~O)~N~C(~O)C1=Ccc +1296,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O +1297,Cyano_pyridone_E,"ac[#6]1=,:[#6!H0]-,:[#6](co)=,:[#6](C#[NX1])-,:[#6](=[OX1])-,:[#7!H0]1",*cC1=CC(co)=C(C#N)C(=O)N1 +1298,Cyano_pyridone_G,"N1(c2ccc(O[CH2,CH3])cc2)C(=[OX1])C(C#[NX1])=CC(n3cncc3)=N1",*Oc1ccc(N2N=C(n3ccnc3)C=C(C#N)C2=O)cc1 +1299,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12 +1300,Thio_aldehyd_A,"[#1,#6][C!H0](=[SX1])",*C=S +1301,Thio_amide_A,"[#6!H0]1=,:[#6]-,:[#8]-,:[#6](=,:[#6!H0]1)C(=[SX1])N5[CH2][CH2]*[CH2][CH2]5",S=C(C1=CC=CO1)N1[CH2][CH2]*[CH2][CH2]1 +1302,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc +1303,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1 +1304,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C +1305,Thio_amide_E,"c1cccnc1C(=S)[N!H0]c2ccccc2O[CH2,CH3]",*Oc1ccccc1NC(=S)c1ccccn1 +1306,Thio_amide_F,acC(=S)[N!H0][N!H0]ca,*cNNC(=S)c* +1307,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1 +1308,Thio_ester_B,"ccC(=[SX1])[SX2][C!H0][CH2,CH3,$(cc)]",*CSC(=S)cc +1309,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1 +1310,Thio_ene_amine_A,"S=CC([CH2,CH3])=C([CH2,CH3])N([CH2,CH3])[CH2,CH3]",*C(C=S)=C(*)N(*)* +1311,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O +1312,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1 +1313,Thio_pyridine_A,c1(nanc(c2o[cH][cH][cH]2)n1)S[CX4],CSc1n*nc(c2[cH][cH][cH]o2)n1 +1314,Thio_thiomorph_Z,"[OX1]=C(N3CCSCC3)c9c([cH][cH][cH][cH]9)S[CH2,CH3]",*Sc1[cH][cH][cH][cH]c1C(=O)N1CCSCC1 +1315,Thio_urea_A,"c1c([N!H0][CX3](=[SX1])[N!H0][CH2][CH2][CH2]N([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1316,Thio_urea_B,"c1c([#7!H0]C(=S)[#7!H0][CH2][CH2][#7]([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1317,Thio_urea_C,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]C(=[OX1])c2a[a!c]cc2,O=C(NNC(=S)Nc1ccccc1)c1*:*cc1 +1318,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1 +1319,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1 +1320,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1 +1321,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1 +1322,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1 +1323,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1 +1324,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S +1325,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12 +1326,Thio_urea_L,[CX4][SX2]C(=N-aaaa)[N!H0]N=[#6],*:*:*:*N=C(NN=C)SC +1327,Thio_urea_M,"cc[#7]([CH2,CH3])[CH2][CH2][CH2][#7!H0]C(=S)[#7!H0]c1c([F,Cl,Br,I])[cH]c([CH2,CH3])[cH][cH]1",*c1[cH][cH]c(NC(=S)N[CH2][CH2][CH2]N(*)cc)c(*)[cH]1 +1328,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1 +1329,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1 +1330,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2 +1331,Thio_urea_Q,"[cH]1[cH][cH][cH]c2[cH][cH][cH]c(c12)C([CH2,CH3])=N[N!H0]C(=S)[N!H0]ccc",*C(=NNC(=S)Nccc)c1[cH][cH][cH]c2[cH][cH][cH][cH]c12 +1332,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1 +1333,Thio_carbam_A,"[CH2,CH3]SC(=S)[N!H0][CH2]-cc",*SC(=S)N[CH2]cc +1334,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1 +1335,Thio_carbonate_B,"[OX1]=[#6]1-,:[#16]c2cccc(O[CH2,CH3])c2-,:[#8]1",*Oc1cccc2c1OC(=O)S2 +1336,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N +1337,Thio_imine_ium,"[CX4][#7+,#7v4]([CX4][OH1])=CS[C!H0]",CSC=*(C)C[OH] +1338,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12 +1339,Thiophene_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=CC(=[OX1])c1c([SX2])sc([$(C#[NX1]),$(C=[OX1])])c1",*c1cc(C(=O)C=CN(*)*)c(S)s1 +1340,Thiophene_D,"s1[cH][cH]c(O[CH2,CH3])c1C(=[OX1])[N!H0][N!H0]",*Oc1[cH][cH]sc1C(=O)NN +1341,Thiophene_E,"c1(sc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])C(=[OX1])[NH]c2nccs2",*C(C(=O)[NH]c1nccs1)c1[cH][cH]c(*)s1 +1342,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C +1343,Thiophene_amino_B,"c2ccccc2[#7!H0]c1sc([$([#6]=[#8]),$(C#[#7]),$([#6]([#8!H0])=[#6])])c([#7])c1[$(C#[#7]),$([#6](n)n)]",*c1sc(Nc2ccccc2)c(*)c1N +1344,Thiophene_amino_C,"[C!H0][CH2]c1sc([N!H0]C(=[OX1])CCC=[OX1])c([$(C(=[OX1])O),$(C#[NX1])])c1[CH2,CH3]",*c1c([CH2]C)sc(NC(=O)CCC=O)c1* +1345,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N +1346,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1 +1347,Thiophene_amino_F,[NH2]c1sc([NH]C(=[OX1])c3ccccc3)c(C#[NX1])c1c2aaaaa2,N#Cc1c([NH]C(=O)c2ccccc2)sc([NH2])c1c1*:*:*:*:*1 +1348,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH] +1349,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc +1350,Keto_naphthol_A,"[#6]C(=[OX1])c1cccc2cccc([OH1,NH2])c12",*c1cccc2cccc(C(C)=O)c12 +1351,Keto_thiophene,"c1(sc2ccccc2c1([CH2,CH3]))C(=[OX1])[CH2][CH2,CH3]",*[CH2]C(=O)c1sc2ccccc2c1* +1352,Keto_phenone_A,c1cccc5c1C(c8c5nacc8)=[OX1],O=C1c2ccccc2c2n*ccc21 +1353,Keto_phenone_B,c1cccc5c1C(C8C5=N[!#1!#6]=CC8)=[OX1],O=C1C2CC=*N=C2c2ccccc21 +1354,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12 +1355,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1 +1356,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1 +1357,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O +1358,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH] +1359,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O +1360,Keto_keto_beta_F,"[CH2,CH3]C([OH1])=C(C(=[OX1])[CH2,CH3])[C!H0]C#C",*C(=O)C(CC#C)=C(*)[OH] +1361,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21 +1362,Thiaz_ene_C,"[#6]1([F,Cl,Br,I,$([#7v4R,#7v4R+](=,:[#6R])-,:[#6R])])=,:[#6](-!@C=N)-,:[#16]-,:[#6](=[OX1])-,:[#7]1",*C1=C(C=N)SC(=O)N1 +1363,Acyl_het_A,"[#7v4,#7+](=,:*-,:*=,:*)-,:*=O",*=**=**=O +1364,Anil_di_alk_G,"[CX4]N([CX4])c1[cH][cH]c([#6]2=,:[#7]-,:[#6]=,:[#6]-,:*2)[cH][cH]1",CN(C)c1[cH][cH]c(C2=NC=C*2)[cH][cH]1 +1365,Anil_di_alk_H,"[cH]1c([N!H0]S(=[OX1])(=[OX1])c2caccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NS(=O)(=O)c2c*ccc2)[cH]1 +1366,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1 +1367,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21 +1368,Anil_di_alk_O,"[cH]1c([N!H0]C(=S)[N!H0]c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=S)Nc2ccccc2)[cH]1 +1369,Anil_di_alk_P,"[CH2,CH3]N([CH2,CH3])c1cc2nc(S[CH2,CH3])sc2cc1",*Sc1nc2cc(N(*)*)ccc2s1 +1370,Anil_di_alk_ene_A,"[CH2,CH3]N([CH2,CH3])C1=[C!H0]c2ccccc2[SX2]c3ccccc13",*N(*)C1=Cc2ccccc2Sc2ccccc21 +1371,Anil_di_alk_dhp,"N1C=C(C=[OX1])C(-c3ccc(N([CH2,CH3])[CH2,CH3])cc3)C2=C1(~[#7]~[#6](~[#16])~[#7]~[#6]2~[#7])",*N(*)c1ccc(C2C(C=O)=CNC3=C2C(~N)~N~C(~S)~N~3)cc1 +1372,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21 +1373,Anil_di_alk_coum,"c2ccccc2N([C!H0])[C!H0][C!H0][C!H0][N!H0]C(=[OX1])[#6]1-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6](=[OX1])-,:[#8]-,:[#6]([CH2,CH3])=,:1",*C1=CC(=O)OC(*)=C1C(=O)NCCCN(C)c1ccccc1 +1374,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1 +1375,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O +1376,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O +1377,Ene_one_amide_A,"c1ccccc1[C!H0]NC(=[OX1])C([N!H0][CH2,CH3])=[C!H0]C(=[OX1])c2ccc(O[CH2,CH3])cc2",*NC(=CC(=O)c1ccc(O*)cc1)C(=O)NCc1ccccc1 +1378,Ene_one_amide_B,"c13ccc2ccccc2c1[C!H0][CX4]NC3=[C!H0]C(=[OX1])N([CH2,CH3])[CH2,CH3]",*N(*)C(=O)C=C1NCCc2c1ccc1ccccc21 +1379,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1 +1380,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O +1381,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C +1382,Imine_one_B,"[N!H0](c1ccccc1)N=C(C(=[OX1])[CH2,CH3])[N!H0][$([N!H0]),$(cc)]",*NC(=NNc1ccccc1)C(*)=O +1383,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1 +1384,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1 +1385,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21 +1386,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C +1387,Imine_imine_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=NC([CH2,CH3])=NN([CH2,CH3])cc",*C(N=CN(*)*)=NN(*)cc +1388,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O +1389,Imine_one_fives_C,cc[N!R]=C2C(=[!#1!#6])c5ccccc5N2,*=C1C(=Ncc)Nc2ccccc21 +1390,Imine_one_fives_D,C1(=[!#1!#6])C(N=CS1)=O,*=C1SC=NC1=O +1391,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH] +1392,Imine_naphthol_A,"c12c([cH][cH][cH][cH]1)c(c([cH][cH]2)C(=N-cc)[CH2,CH3])[OH1]",*C(=Ncc)c1[cH][cH]c2[cH][cH][cH][cH]c2c1[OH] +1393,Pyrrole_C,"[#7]1([CX4])-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6!H0]=,:[#6]1cc",*C1=CC=C(cc)N1C +1394,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S +1395,Pyrrole_E,"[#7]1(c2[cH]a[a!c]a2)-,:[#6]([CX4])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CX4]",CC1=CC=C(C)N1c1*:*:*[cH]1 +1396,Pyrrole_F,[cH]1[cH]n(-c2[a!c]ccc2C#[NX1])c[cH]1,N#Cc1cc*c1-n1c[cH][cH][cH]1 +1397,Pyrrole_G,"n1(c2c[cH]c([$([NH2]),$(cn)])c[cH]2)[cH][cH][cH][cH]1",*c1c[cH]c(n2[cH][cH][cH][cH]2)c[cH]1 +1398,Pyrrole_H,"C1=[Nv4,N+]([#6])CC[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]12",C*1=CC2=CC=CN2CC1 +1399,Pyrrole_I,"[#7]1([CH2,CH3])-,:[#6]2=,:[#6](-,:[#6]:[#6]-,:[#6]2=[OX1])-,:[#6]=,:[#6]1[CH2,CH3]",*C1=CC2=C(C(=O)C:C2)N1* +1400,Pyrrole_J,"[#6]1(=,:[#6]2-,:[#6](=,:[#6](-,:[#7]1C(O)=[OX1])[CH2,CH3])S[CH2]S2)[CH2,CH3]",*C1=C2S[CH2]SC2=C(*)N1C(O)=O +1401,Pyrrole_K,"[#6]1(-,:[#7!H0]-,:[#6](c2[cH][cH][cH][cH][cH]2)=,:[#6]([CH2,CH3])-,:[#6H]=,:1)C(=[OX1])[OH1]",*C1=C(c2[cH][cH][cH][cH][cH]2)NC(C(=O)[OH])=[CH]1 +1402,Pyrrole_L,"[n!H0]1c(C(=[OX1])O[CH2,CH3])c([CH2,CH3])c([CH2][CH2,CH3])c1[CH2][CH2,CH3]",*[CH2]c1nc(C(=O)O*)c(*)c1[CH2]* +1403,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1 +1404,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1 +1405,Pyrrole_O,"[#7]1([CH2,CH3])-,:[#6]([CH2,CH3])=,:[#6](C(=[OX1])[#6])-,:[#6]=,:[#6]1-cc",*C1=C(C(C)=O)C=C(cc)N1* +1406,Thiaz_ene_D,"c2ccccc2[#7][#6]1=,:[#7+,#7v4]-,:[#6](c3ccccc3)=,:[#6][#16]1",*1=C(Nc2ccccc2)SC=C1c1ccccc1 +1407,Thiaz_ene_E,"C1(S[#6R])=C([C!H0]([#6])[#6])SC(N1([H,CH2,CH3]))=[OX1]",*N1C(=O)SC(C(C)C)=C1SC +1408,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21 +1409,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O +1410,Quinone_D,"[!#1!#6]=[#6]1[#6]=,:[#6][#6]=,:[#6][#6]1=[!#1!#6]",*=C1C=CC=CC1=* +1411,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1 +1412,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1 +1413,Diazox_C,N2=Nc1n[a!c]nc1N=Ncc2,*1nc2c(n1)N=NccN=N2 +1414,Diazox_D,[C!H0]1([OH1])c2n[a!c]nc2[C!H0]([OH1])C=C1,[OH]C1C=CC([OH])c2n*nc21 +1415,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2] +1416,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1 +1417,Sulfonamide_C,[cH]1c([N!H0]S(=[OX1])(=[OX1])c2ccc([!#1!#6])cc2)[cH]c3c(O[CH2]O3)[cH]1,*c1ccc(S(=O)(=O)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)cc1 +1418,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1 +1419,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc +1420,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1 +1421,Sulfonamide_G,"[CH3]c5nc([N!H0]S(c2[cH][cH]c([cH][cH]2)O[CH2][CH2][CH2,CH3])(=[OX1])(=[OX1]))[cH][cH][cH]5",*[CH2][CH2]Oc1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]c([CH3])n2)[cH][cH]1 +1422,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1 +1423,Sulfonamide_I,"S(=[OX1])(=[OX1])(c1cn([CH2,CH3])cn1)[N!H0]c2cnn([CH2]ccO[CH2,CH3])c2",*Occ[CH2]n1cc(NS(=O)(=O)c2cn(*)cn2)cn1 +1424,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1 +1425,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc +1426,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1 +1427,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1 +1428,Thiazole_amine_B,"c1(ccc([CH2,CH3])cc1)-c2nc([NH2])sc2[CH3]",*c1ccc(-c2nc([NH2])sc2[CH3])cc1 +1429,Thiazole_amine_C,"c1([N!H0][CH2]c2[cH][cH][cH]o2)nc(aaa([$(O[CH2,CH3]),CH2,CH3])aa)[cH]s1",**(:*:*):*:*c1[cH]sc(N[CH2]c2[cH][cH][cH]o2)n1 +1430,Thiazole_amine_D,"[#16]1-,:[#6]([N!H0]c2c([CH2,CH3,$(cc)])cccc2)=,:[#7+,#7v4]([CH2,CH3])-,:[#6]([#6])=,:[#6H]1",**1=C(Nc2ccccc2*)S[CH]=C1C +1431,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O +1432,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1 +1433,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1 +1434,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1 +1435,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1 +1436,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3 +1437,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1 +1438,Thiazole_amine_M,"c1([N!H0]cc[CH2,CH3])nc(c2ccncc2)[cH]s1",*ccNc1nc(c2ccncc2)[cH]s1 +1439,Thiazole_amine_N,"[CH2,CH3]Oc1[cH][cH]c(O[CH2,CH3])[cH]c1[N!H0]c2scc(-c3ccc(O[CH2,CH3])cc3)n2",*Oc1ccc(-c2csc(Nc3[cH]c(O*)[cH][cH]c3O*)n2)cc1 +1440,Furan_acid_A,"c1(oc([CH2,CH3])c([CH2]Occ)[cH]1)[CX3](=[OX1])[OH1]",*c1oc(C(=O)[OH])[cH]c1[CH2]Occ +1441,Furan_A,"c1(oc([CH2,CH3])[cH][cH]1)[C!H0]([OH1])C#C[CX4]",*c1[cH][cH]c(C([OH])C#CC)o1 +1442,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N +1443,Colchicine_B,"[CH2,CH3]Sc1ccc(cc1)C2=CC(=[OX1])[#6]3=,:[#6]-,:[#8]-,:[#6]=,:[#6]3C([OH1])=C2",*Sc1ccc(C2=CC(=O)C3=COC=C3C([OH])=C2)cc1 +1444,Colchicine_het,"c1cccc3-,:[#7]([CH2,CH3])-,:[#6](=NN=[#6]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]2)-,:[#16]-,:c13",*N1C(=NN=C2C=CC=CC=C2)Sc2ccccc21 +1445,Rhod_sat_B,"N1(c2c([CH2,CH3])cccc2)C(=S)N([CH2]aaaaa)[CH2]C1=[OX1]",*c1ccccc1N1C(=O)[CH2]N([CH2]*:*:*:*:*)C1=S +1446,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1 +1447,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O +1448,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1 +1449,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1 +1450,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1 +1451,Melamine_A,"o1[cH][cH][cH]c1[CH2][N!H0]c1c2ccccc2nc([N!H0]c4c([H,CH2,CH3,SX2,$(O[C!H0])])cc([H,CH2,CH3,SX2,$(O[C!H0])])c([H,CH2,CH3,SX2,$(O[C!H0])])c4)n1",*c1cc(*)c(Nc2nc(N[CH2]c3[cH][cH][cH]o3)c3ccccc3n2)cc1* +1452,Melamine_B,"n1c(N([CH2,CH3])[CH2,CH3])nc(N([CH2,CH3])[CH2,CH3])nc1N([C!H0])C=[OX1]",*N(*)c1nc(N(*)*)nc(N(C)C=O)n1 +1453,Imidazole_B,"[CH2,CH3][CH2]S[CH2][#6]1=,:[#6]-,:[#7!H0]-,:[#6]=,:[#7]1",*[CH2]S[CH2]C1=CNC=N1 +1454,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2 +1455,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1 +1456,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1 +1457,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23 +1458,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2 +1459,Naphth_ene_one_A,"c1cc3c4c(c1)cccc4C(=CC3=[OX1])O[CH2,CH3]",*OC1=CC(=O)c2cccc3cccc1c23 +1460,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F +1461,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2 +1462,Coumarin_A,"c1(O[C!H0])[cH][cH]c2c3[cH][cH]c(O[CH2,CH3])[cH]c3-,:[#6](=[OX1])-,:[#8]c2c1",*Oc1[cH][cH]c2c([cH]1)C(=O)Oc1cc(OC)[cH][cH]c12 +1463,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O +1464,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1 +1465,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1 +1466,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1 +1467,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O +1468,Coumarin_G,"c1c([F,Cl,Br,I])cc2c(c1[F,Cl,Br,I])OC(=[N!H0])C(C(=[OX1])[NH2])=[C!H0]2",*c1cc(*)c2c(c1)C=C(C([NH2])=O)C(=N)O2 +1469,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1 +1470,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O +1471,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O +1472,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1 +1473,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH] +1474,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH] +1475,Tetrazole_A,"[CH2,CH3][#6]1=,:[#7]-,:[#7]=,:[#7]-,:[#7]1c2[cH][cH]c(O[CH3])[cH][cH]2",*C1=NN=NN1c1[cH][cH]c(O[CH3])[cH][cH]1 +1476,Misc_aminal_acid,"c1ccc4c(c1)COC(N4C(=[OX1])[CH2,CH3])(C(=[OX1])[OH1])[CH2,CH3]",*C(=O)N1c2ccccc2COC1(*)C(=O)[OH] +1477,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1 +1478,Misc_anilide_A,"c1([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH][cH]c([CH2,CH3])c([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH]1",*c1[cH][cH]c(NC(=O)[CH2][CH2]cc)[cH]c1NC(=O)[CH2][CH2]cc +1479,Misc_anilide_B,"c1([N!H0]C(=[OX1])[N!H0][CH2][CH2][CH2,CH3])c([CH2,CH3])[cH]c(Br)[cH]c1[CH2,CH3]",*[CH2][CH2]NC(=O)Nc1c(*)[cH]c(Br)[cH]c1* +1480,Misc_anisole_A,"c1(c([cH]c5c([cH]1)c([cH]c([cH]5)c3[cH][cH]c(c([cH]3)O[CH2,CH3])O[CH2,CH3])[N!H0][CH3])O[CH2,CH3])O[CH2,CH3]",*Oc1[cH][cH]c(c2[cH]c(N[CH3])c3[cH]c(O*)c(O*)[cH]c3[cH]2)[cH]c1O* +1481,Misc_anisole_B,"c1([cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH][cH]1)C(=[OX1])[CH2]N([CH2,CH3])c2ccc([CH2,CH3])cc2",*Oc1[cH][cH]c(C(=O)[CH2]N(*)c2ccc(*)cc2)[cH]c1O* +1482,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3] +1483,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1 +1484,Misc_furan_A,"c3c([CH2,CH3])c([CH2,CH3])oc3[CH2]N[CH2][C!H0](O[CH2,CH3])[CH2]Oc1ccc2c(O[CH2]O2)c1",*OC([CH2]N[CH2]c1cc(*)c(*)o1)[CH2]Oc1ccc2c(c1)O[CH2]O2 +1485,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1 +1486,Misc_phthal_thio_N,"c1(c2ccccc2)nc(N([CH2,CH3])[CH2][CH2]NC(=[OX1])c3c(C(=[OX1])[OH1])cccc3)sn1",*N([CH2][CH2]NC(=O)c1ccccc1C(=O)[OH])c1nc(c2ccccc2)ns1 +1487,Misc_pyridine_OC,"[OX1]=C(c1[cH]c(O[CH3])nc(O[CH3])[cH]1)[N!H0][C!H0]([CH2,CH3])[CH2,CH3]",*C(*)NC(=O)c1[cH]c(O[CH3])nc(O[CH3])[cH]1 +1488,Misc_pyrrole_benz,"[#7]1(-c2[cH][cH][cH][cH]c2C(=[OX1])[N!H0][C!H0]([CH2,CH3])[CH2]O-cc)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",*C([CH2]Occ)NC(=O)c1[cH][cH][cH][cH]c1N1C=CC=C1 +1489,Misc_pyrrole_thiaz,"c1([C!H0]([CH2,CH3])[CH2][CH2]N[CH2]c2[n!H0]ccc2)nc(-c3ccccc3)[c!H0]s1",*C([CH2][CH2]N[CH2]c1cccn1)c1nc(-c2ccccc2)cs1 +1490,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH] +1491,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH] +1492,Misc_urea_A,"c1(C([CX4])([CX4])[N!H0]C(=[OX1])N([CH2][CH2,CH3])[CH2][CH2][CH2][CH2]-cc)[cH][cH][cH]c(C(=[CH2])[CH2,CH3])[cH]1",*[CH2]N([CH2][CH2][CH2][CH2]cc)C(=O)NC(C)(C)c1[cH][cH][cH]c(C(*)=C)[cH]1 +1493,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1 +1494,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1 +1495,Pyrazole_amino_A,"[#6]1=,:[#6]([NH2])-,:[#7]-,:[#7]=,:[#6]1-[#6]2=,:[#6]([CH2,CH3])-,:[#8]-,:[#6!H0]=,:[#6!H0]2",*C1=C(C2=NNC([NH2])=C2)C=CO1 +1496,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1 +1497,Indole_3yl_alk_B,"c12[cH][cH][cH][cH]c1-,:[#6]([CH2,CH3])=,:[#6](-cc)-,:[#7]2-!@cc",*C1=C(cc)N(cc)c2[cH][cH][cH][cH]c21 +1498,Mannich_B,"c1c[cH]c2O[CH2]N(ccO[CH2,CH3])[CH2]c2[cH]1",*OccN1[CH2]Oc2[cH]cc[cH]c2[CH2]1 +1499,Mannich_catechol_A,"[cH]1c([#8])c([#8])[cH]c2c1O[CH2]N([CH2,CH3])[CH2]2",*N1[CH2]Oc2[cH]c(O)c(O)[cH]c2[CH2]1 +1500,Dyes7A,"c1ccccc1N([CH2,CH3])[C!H0]=[C!H0]C=!@[C!H0][C!H0]=CC=&@Nc2ccccc2",*N(C=CC=CC=CC=Nc1ccccc1)c1ccccc1 +1501,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1 +1502,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1 +1503,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH] +1504,Retinoic acid derivatives_1,"[$([OH1][CX3](=[OX1])c1[cH][cH]c(-c2c[cH]c3[cH]c([H,CX4])c([H,CX4])[cH]c3[cH]2)[cH][cH]1),$([OH1][CX3](=[OX1])c1[cH]c2[cH]cc(-c3[cH]c([H,CX4])c([H,CX4])[cH][cH]3)[cH]c2[cH][cH]1)]",* +1505,Thiazole_amine_I,"[CH2,CH3][N!H0]C=N[N!H0][#6]1=,:[#7]-,:[#6](-cc)=,:[#6!H0]-,:[#16]1",*NC=NNC1=NC(cc)=CS1 +1506,Indol_3yl_alk,"[H,CH2,CH3][#7]1-,:[#6]([CH2,CH3,$([a!c](:[#6]-,:[#7])),$([C!H0][#7]),$([C!H0]([CH2,CH3])[N!H0][CH2,CH3]),$([C!H0]([CH2,CH3])[CH2][N!H0][CH2,CH3])])=,:[#6]([CX4!H0])-,:c2[cH]cccc12",*C1=C(C)c2[cH]cccc2N1* +1507,Tetrazole_hzide,"a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])[N!H0][N!H0][#6]2=,:[#7]-,:[#7]=,:[#7]-,:[#7]2[#6]",CN1N=NN=C1NNC(=O)C=C*1:*:*:*:*:*:1 +1508,Three-membered heterocycles (LS),[!#6!#1]1~*~*~1,*1~*~*~1 +1509,Three-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~1,*1~C~C~1 +1510,Saturated three-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-1,*1CC1 +1511,Unsaturated three-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1~[#6]=[#6]~1),$([!#1!#6]1=[#6]~[#6]~1)]",* +1512,Three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[#6]~1,*1~*~C~1 +1513,Saturated three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[#6]-1,*1*C1 +1514,Unsaturated three-membered heterocycles with two heteroatoms (LS),"[$([!#1!#6]1=[!#1!#6]~[#6]~1),$([!#1!#6]1~[!#6!#1]=[#6]~1)]",* +1515,Three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~1,*1~*~*~1 +1516,Saturated three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-1,*1**1 +1517,Unsaturated three-membered heterocycles with three heteroatoms (LS),[!#1!#6]1~[!#1!#6]=[!#1!#6]~1,*1~*=*~1 +1518,Three-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~1,*1~*~*~1 +1519,Three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6&R1]~[#6&R1]~1,*1~C~C~1 +1520,Saturated three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6&R1]-[#6&R1]-1,*1CC1 +1521,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1 +1522,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1 +1523,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1 +1524,Unsaturated three-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1~[#6R1]=[#6R1]~1),$([!#1!#6;R1]1=[#6R1]~[#6R1]~1)]",* +1525,Azirines (HS),"[$([#7R1]1-[#6R1]=[#6R1]-1),$([#7R1]1=[#6R1]-[#6R1]-1)]",* +1526,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1 +1527,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1 +1528,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1 +1529,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1 +1530,Three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~1,*1~*~C~1 +1531,Saturated three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-1,*1*C1 +1532,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1 +1533,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1 +1534,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1 +1535,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1 +1536,Unsaturated three-membered heterocycles with two heteroatoms (HS),"[$([!#1!#6;R1]1=[!#1!#6;R1]~[#6R1]~1),$([!#1!#6;R1]1~[!#6!#1;R1]=[#6R1]~1)]",* +1537,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1 +1538,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1 +1539,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1 +1540,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1 +1541,Three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~1 +1542,Saturated three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**1 +1543,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1 +1544,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1 +1545,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1 +1546,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1 +1547,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1 +1548,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1 +1549,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1 +1550,Unsaturated three-membered heterocycles with three heteroatoms (HS),[!#1!#6;R1]1-[!#6!#1;R1]=[!#6!#1;R1]1,*1*=*1 +1551,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1 +1552,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1 +1553,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1 +1554,Four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~1)]",* +1555,Saturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1-[!#6!#1]-[#6]-[#6]-1),$([!#6!#1]1-[#6]-[!#6!#1]-[#6]-1)]",* +1556,Unsaturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]=[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]=[#6]~1),$([!#6!#1]1=[#6]~[!#6!#1]~[#6]~1)]",* +1557,Four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~C~*~1 +1558,Saturated four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[#6]-1,*1*C*1 +1559,Unsaturated four-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]=[#6]~1)]",* +1560,Four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~1 +1561,Saturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1***1 +1562,Unsaturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*=*~1 +1563,Four-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~1 +1564,Four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~1 +1565,Saturated four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6R1]-[#6R1]-[#6R1]-1,*1CCC1 +1566,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1 +1567,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1 +1568,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1 +1569,Unsaturated four-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]=[#6R1]~[#6R1]~1)]",* +1570,Azetines (HS),"[$([#7R1]1=[#6R1]-[#6R1]-[#6R1]-1),$([#7R1]1-[#6R1]=[#6R1]-[#6R1]-1)]",* +1571,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1 +1572,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1 +1573,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1 +1574,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1 +1575,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1 +1576,Four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1577,Saturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-[#6R1]-1),$([!#6!#1;R1]1-[#6R1]-[!#6!#1;R1]-[#6R1]-1)]",* +1578,Diazetidines (HS),"[$([NR1]1[CR1][CR1][NR1]1),$([NR1]1[CR1][NR1][CR1]1)]",* +1579,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1 +1580,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1 +1581,Dioxetanes (HS),"[$([OR1]1[OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]1)]",* +1582,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1 +1583,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1 +1584,Dithietanes (HS),"[$([SX2R1]1[SX2R1][CR1][CR1]1),$([SX2R1]1[CR1][SX2R1][CR1]1)]",* +1585,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1 +1586,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1 +1587,Unsaturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]=[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]=[#6R1]~1),$([!#6!#1;R1]1=[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1588,Diazetines (HS),"[$([#7]1=,:[#7]-,:[#6]-,=,:[#6]-,:1),$([#7]1-,:[#7]=,:[#6]-,:[#6]-,=,:1),$([#7]1-,:[#7]-,:[#6]=,:[#6]-,=,:1),$([#7]1=,:[#6]-,:[#7]-,=,:[#6]-,:1)]",* +1589,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1 +1590,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1 +1591,Four-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~1,*1~C~C~C~1 +1592,Saturated four-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-[#6]-1,*1CCC1 +1593,Unsaturated four-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]=[#6]~[#6]~1)]",* +1594,Diazirenes (HS),"[$([#7R1]1-[#7R1]=[#6R1]-1),$([#7R1]1=[#7R1]-[#6R1]-1)]",* +1595,Four-membered heterocycles (LS),[!#6!#1]1~*~*~*~1,*1~*~*~*~1 +1596,Five-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~1,*1~*~*~*~*~1 +1597,Five-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~1 +1598,Saturated five-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCC1,*1CCCC1 +1599,Unsaturated five-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=CCCC1),$([!#6!#1]1C=CCC1),$([!#6!#1]1CC=CC1),$([!#6!#1]1=CC=CC1);!$(n1cccc1)]",* +1600,Aromatic five-membered heterocycles with one heteroatom (LS),[a!#6]1cccc1,*1cccc1 +1601,Five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1602,Saturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCC1),$([!#6!#1]1C[!#6!#1]CC1)]",* +1603,Unsaturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]C-,=CC1),$([!#6!#1]1[!#6!#1]=CCC1),$([!#6!#1]1[!#6!#1]C=CC1),$([!#6!#1]1=C[!#6!#1]-,=CC1),$([!#6!#1]1C[!#6!#1]CC=1),$([!#6!#1]1C[!#6!#1]C=C1)]",* +1604,Aromatic five-membered heterocycles with two heteroatoms (LS),"[$([a!#6]1[a!#6]ccc1),$([a!#6]1c[a!#6]cc1)]",* +1605,Five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1606,Saturated five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]C1)]",* +1607,Aromatic five-membered heterocycles with three heteroatoms (LS),"[$([a!#6]1[a!#6][a!#6]cc1),$([a!#6]1[a!#6]c[a!#6]c1)]",* +1608,Five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~1 +1609,Saturated five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]C1,*1**C*1 +1610,Unsaturated five-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1][!#6!#1]-,=[!#6!#1][#6]1),$([!#6!#1]1[!#6!#1]=[!#6!#1][!#6!#1][#6]1),$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1][#6]=1)]",* +1611,Aromatic five-membered heterocycles with four heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6]c1,*1:*:*c*:1 +1612,Five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~1 +1613,Saturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1****1 +1614,Unsaturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1=[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1**=**1 +1615,Aromatic five-membered heterocycles with five heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6][a!#6]1,*1:*:*:*:*:1 +1616,Five-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~1 +1617,Five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~1 +1618,Saturated five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1]1,*1CCCC1 +1619,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1 +1620,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1 +1621,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1 +1622,Unsaturated five-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1]=[CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1]=[CR1][CR1]1),$([!#6!#1;R1]1=[CR1][CR1]=[CR1][CR1]1);!$(n1cccc1)]",* +1623,Pyrrolines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1624,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1 +1625,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1 +1626,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1 +1627,Dihydrofurans (HS),"[$([OR1]1[CR1]=[CR1][CR1][CR1]1),$([OR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1628,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1 +1629,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1 +1630,Dihydrothiophenes (HS),"[$([SR1]1[CR1]=[CR1][CR1][CR1]1),$([SR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1631,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1 +1632,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1 +1633,Aromatic five-membered heterocycles with one heteroatom (HS),[a!#6;R1]1[cR1][cR1][cR1][cR1]1,*1cccc1 +1634,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1 +1635,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1 +1636,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1 +1637,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1 +1638,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1 +1639,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1 +1640,Five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1)]",* +1641,Saturated five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1]1)]",* +1642,Diazolidines (HS),"[$([NR1]1[NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1]1)]",* +1643,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1 +1644,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1 +1645,Dioxolanes (HS),"[$([OR1]1[OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1]1)]",* +1646,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1 +1647,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1 +1648,Dithiolanes (HS),"[$([SR1]1[SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1]1)]",* +1649,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1 +1650,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1 +1651,Pyrazolines (HS),"[$([NR1]1=[NR1][CR1][CR1][CR1]1),$([NR1]1[NR1]=[CR1][CR1][CR1]1),$([NR1]1[NR1][CR1]=[CR1][CR1]1)]",* +1652,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1 +1653,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1 +1654,Imidazolines (HS),"[$([NR1]1=[CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1]=[CR1][CR1]1),$([NR1]1[CR1][NR1][CR1]=[CR1]1)]",* +1655,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1 +1656,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1 +1657,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1 +1658,Dioxolenes (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]=[CR1]1)]",* +1659,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1 +1660,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1 +1661,Dithiolenes (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]1),$([SR1]1[CR1][SR1][CR1]=[CR1]1)]",* +1662,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1 +1663,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1 +1664,Aromatic five-membered heterocycles with two heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][cR1][cR1][cR1]1),$([a!#6;R1]1[cR1][a!#6;R1][cR1][cR1]1)]",* +1665,Diazoles (HS),"[$([nR1]1[nR1][cR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][cR1]1)]",* +1666,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1 +1667,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1 +1668,Oxazoles (HS),"[$([oR1]1[nR1][cR1][cR1][cR1]1),$([oR1]1[cR1][nR1][cR1][cR1]1)]",* +1669,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1 +1670,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1 +1671,Thiazoles (HS),"[$([sR1]1[nR1][cR1][cR1][cR1]1),$([sR1]1[cR1][nR1][cR1][cR1]1)]",* +1672,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1 +1673,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1 +1674,Five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1675,Saturated five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1676,Triazolidines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1]1)]",* +1677,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1 +1678,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1 +1679,Trioxolanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1]1)]",* +1680,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1 +1681,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1 +1682,Trithiolanes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1]1)]",* +1683,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1 +1684,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1 +1685,"1,2,3-Triazolines (HS)","[$([NR1]1=[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][NR1][CR1][CR1]=1),$([NR1]1[NR1][NR1][CR1]=[CR1]1)]",* +1686,"1,2,4-Triazolines (HS)","[$([NR1]1=[NR1][CR1][NR1][CR1]1),$([NR1]1[NR1]=[CR1][NR1][CR1]1),$([NR1]1[NR1][CR1]=[NR1][CR1]1)]",* +1687,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1 +1688,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1 +1689,Aromatic five-membered heterocycles with three heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][a!#6;R1][cR1][cR1]1),$([a!#6;R1]1[a!#6;R1][cR1][a!#6;R1][cR1]1)]",* +1690,Triazoles (HS),"[$([nR1]1[nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1]1)]",* +1691,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1 +1692,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1 +1693,Oxadiazoles (HS),"[$([oR1]1[nR1][nR1][cR1][cR1]1),$([oR1]1[nR1][cR1][nR1][cR1]1),$([oR1]1[nR1][cR1][cR1][nR1]1),$([oR1]1[cR1][nR1][nR1][cR1]1)]",* +1694,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1 +1695,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1 +1696,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1 +1697,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1 +1698,Five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~1 +1699,Saturated five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1][CR1]1,*1**C*1 +1700,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1 +1701,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1 +1702,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1 +1703,Unsaturated five-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1][!#6!#1;R1]-,=[!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1]=[!#6!#1;R1][!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][#6R1]=1)]",* +1704,Aromatic five-membered heterocycles with four heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][cR1]1,*1:*:*c*:1 +1705,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1 +1706,Oxatriazoles (HS),"[$([oR1]1[nR1][nR1][nR1][cR1]1),$([oR1]1[nR1][nR1][cR1][nR1]1)]",* +1707,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1 +1708,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1 +1709,Thiatriazoles (HS),"[$([sR1]1[nR1][nR1][nR1][cR1]1),$([sR1]1[nR1][nR1][cR1][nR1]1)]",* +1710,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1 +1711,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1 +1712,Five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~1 +1713,Saturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1****1 +1714,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1 +1715,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1 +1716,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1 +1717,Unsaturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1=[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**=**1 +1718,Aromatic five-membered heterocycles with five heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][a!#6;R1]1,*1:*:*:*:*:1 +1719,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1 +1720,Six-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~*~1,*1~*~*~*~*~*~1 +1721,Six-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~C~1 +1722,Saturated six-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCCC1,*1CCCCC1 +1723,Unsaturated six-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1=C~C~C~C~C~1),$([!#1!#6]1~C=C~C~C~C~1),$([!#1!#6]1~C~C=C~C~C~1);!$([a!c]1ccccc1)]",* +1724,Aromatic six-membered heterocycles with one heteroatom (LS),[a!c]1ccccc1,*1ccccc1 +1725,Six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1726,Saturated six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCCC1),$([!#6!#1]1C[!#6!#1]CCC1),$([!#6!#1]1CC[!#6!#1]CC1)]",* +1727,Aromatic six-membered heterocycles with two heteroatoms (LS),"[$([a!c]1[a!c]cccc1),$([a!c]1c[a!c]ccc1),$([a!c]1cc[a!c]cc1)]",* +1728,Six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1729,Saturated six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CCC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]CC1),$([!#6!#1]1C[!#6!#1]C[!#6!#1]C1)]",* +1730,Aromatic six-membered heterocycles with three heteroatoms (LS),"[$([a!c]1[a!c][a!c]ccc1),$([a!c]1[a!c]c[a!c]cc1),$([a!c]1c[a!c]c[a!c]c1)]",* +1731,Six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[!#6!#1]~[#6]~1)]",* +1732,Saturated six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1][!#6!#1]C[!#6!#1]C1),$([!#6!#1]1[!#6!#1]C[!#6!#1][!#6!#1]C1)]",* +1733,Aromatic six-membered heterocycles with four heteroatoms (LS),"[$([a!c]1[a!c][a!c][a!c]cc1),$([a!c]1[a!c][a!c]c[a!c]c1),$([a!c]1[a!c]c[a!c][a!c]c1)]",* +1734,Six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~*~1 +1735,Saturated six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-C-1,*1**C**1 +1736,Aromatic six-membered heterocycles with five heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c]c1,*1:*:*c*:*:1 +1737,Saturated six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1*****1 +1738,Unsaturated six-membered heterocycles with six heteroatoms (LS),[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1739,Aromatic six-membered heterocycles with six heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c][a!c]1,*1:*:*:*:*:*:1 +1740,Six-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~*~1 +1741,Six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~C~1 +1742,Saturated six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1][CR1]1,*1CCCCC1 +1743,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1 +1744,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1 +1745,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1 +1746,Unsaturated six-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1=[CR1]~[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]=[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]~[CR1]=[CR1]~[CR1]~[CR1]~1);!$([a!c]1ccccc1)]",* +1747,Tetrahydropyridines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1][CR1]1)]",* +1748,Dihydropyridines (HS),"[$([NR1]1=[CR1][CR1]-,=[CR1]-,=[CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]-,=[CR1]-,=1),$([NR1]1[CR1]=[CR1][CR1]=[CR1][CR1]1)]",* +1749,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1 +1750,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1 +1751,Aromatic six-membered heterocycles with one heteroatom (HS),[a!c;R1]1[cR1][cR1][cR1][cR1][cR1]1,*1ccccc1 +1752,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1 +1753,Six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~1)]",* +1754,Saturated six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1][!#6!#1;R1][CR1][CR1]1)]",* +1755,Hexahydrodiazines,"[$([NR1]1[NR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1][NR1][CR1][CR1]1)]",* +1756,Dioxanes,"[$([OR1]1[OR1][CR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][CR1][OR1][CR1][CR1]1)]",* +1757,Dithianes,"[$([SR1]1[SR1][CR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][CR1][SR1][CR1][CR1]1)]",* +1758,Dioxines (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]=[CR1]1),$([OR1]1[CR1]=[CR1][OR1][CR1]=[CR1]1)]",* +1759,Aromatic six-membered heterocycles with two heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][cR1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][cR1][a!c;R1][cR1][cR1]1)]",* +1760,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1 +1761,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1 +1762,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1 +1763,Six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1764,Saturated six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1765,Hexahydrotriazines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][NR1][CR1]1)]",* +1766,Trioxanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][OR1][CR1]1)]",* +1767,Trithianes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][SR1][CR1]1)]",* +1768,Aromatic six-membered heterocycles with three heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][a!c;R1][cR1]1)]",* +1769,Triazines (HS),"[$([nR1]1[nR1][nR1][cR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][nR1][cR1]1)]",* +1770,Saturated six-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][!#6!#1;R1][CR1]1)]",* +1771,Hexahydrotetrazines (HS),"[$([NR1]1[NR1][NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][NR1][CR1]1),$([NR1]1[NR1][NR1][CR1][NR1][CR1]1)]",* +1772,Tetroxanes (HS),"[$([OR1]1[OR1][OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][OR1][CR1]1)]",* +1773,Tetrathianes (HS),"[$([SR1]1[SR1][SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][SR1][CR1]1)]",* +1774,Aromatic six-membered heterocycles with four heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][a!c;R1][cR1][a!c;R1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][a!c;R1][cR1]1)]",* +1775,Tetrazines (HS),"[$([nR1]1[nR1][nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][nR1][cR1][nR1][cR1]1),$([nR1]1[nR1][cR1][nR1][nR1][cR1]1)]",* +1776,Six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~*~1 +1777,Saturated six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[CR1]-1,*1**C**1 +1778,Aromatic six-membered heterocycles with five heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][cR1]1,*1:*:*c*:*:1 +1779,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1 +1780,Six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~*~1 +1781,Saturated six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1*****1 +1782,Unsaturated six-membered heterocycles with six heteroatoms (HS),[$([!#6!#1;R1]1=[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1783,Aromatic six-membered heterocycles with six heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][a!c;R1]1,*1:*:*:*:*:*:1 +1784,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1 +1785,Six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~*~1 +1786,Dithiines (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]=[CR1]1),$([SR1]1[CR1]=[CR1][SR1][CR1]=[CR1]1)]",* +1787,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1 +1788,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1 +1789,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1 +1790,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C +1791,Allyl halides,"[CX3]=[CX3][CX4][F,Cl,Br,I]",*CC=C +1792,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF +1793,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl +1794,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr +1795,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI +1796,Vinyl fluorides,F[CX3]=[CX3],C=CF +1797,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl +1798,Vinyl bromides,Br[CX3]=[CX3],C=CBr +1799,Vinyl iodides,I[CX3]=[CX3],C=CI +1800,Alkynyl fluorides,F[CX2]#[CX2],C#CF +1801,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl +1802,Alkynyl iodides,I[CX2]#[CX2],C#CI +1803,Alkynyl bromides,Br[CX2]#[CX2],C#CBr +1804,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC +1805,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc +1806,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc +1807,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH] +1808,"1,3 – Diphenols",c([OH1])[aR1]c([OH1]),[OH]c*c[OH] +1809,"1,4 - Diphenols",c1([OH1])aac([OH1])aa1,[OH]c1*:*c([OH])*:*1 +1810,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH] +1811,"1,3 – Dithiophenols",c([SH1])[aR1]c([SH1]),[SH]c*c[SH] +1812,"1,4 – Dithiophenols",c1([SH1])aac([SH1])aa1,[SH]c1*:*c([SH])*:*1 +1813,"1,2 – Aminophenols","c([OH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[OH] +1814,"1,3 – Aminophenols","c([OH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[OH] +1815,"1,4 – Aminophenols","c1([OH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([OH])*:*1 +1816,"1,2 – Aminothiophenols","c([SH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[SH] +1817,"1,3 – Aminothiophenols","c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[SH] +1818,"1,4 – Aminothiophenols","c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([SH])*:*1 +1819,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C +1820,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C +1821,Carbonic acid esters,"[#1,#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*OC(=O)OC +1822,Phosphonic acid amides,[OX1]=[Pv5X4]([NX3])([#6])[!#6!$([SX2])],*P(C)(N)=O +1823,Aldehyde,[CX3H1](=O)[#6],C[CH]=O +1824,AliphaticEther,[!$(C=O);$([C&!a])][OX2&H0][!$(C=O);$([C&!a])],*O* +1825,AminoAcids,"[$([NX3,NX4+][CX4H]([*])[CX3](=[OX1])[O,N]),$([$([$([NX3H2,NX4H3+]),$([NX3H](C)(C))][CX4H2][CX3](=[OX1])[OX2H,OX1-,N])])]",* +1826,AromaticHalogen,"[$([a][F,Cl,I])]",* +1827,AromaticNGroups,"[$([a]N(~O)~O),$([a]N([#1])[*]),$([a]N([#1])[!#1])]",* +1828,AromaticSulphonicAcid,"[$([#16X4](=[OX1])(=[OX1])([a])[OX2H,OX1H0-]),$([#16X4+2]([OX1-])([OX1-])([a])[OX2H,OX1H0-])]",* +1829,AzoGroup,[$([!R&N]=[!R&N])],* +1830,CyanoGroupOnMoreThanEightAtomsChain,[N]#[C]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0],*~*~*~*~*~*~*~*~C#N +1831,Epoxide,[$(C1OC1)],* +1832,Esters,[#6][CX3](=O)[$([OX2H0]([#6])[#6])],*C(C)=O +1833,Formaldehyde,[CX3H2](=O),C=O +1834,Ketone,[C][C](=O)[C],CC(C)=O +1835,MoreThanTwoHydroxyOnAromaticRing,"[$([a&R]([OX2H])[a&R]([OX2H])),$([a&R]([OX2H])a[a&R]([OX2H])),$([a&R]([OX2H])aa[a&R]([OX2H]))]",* +1836,Nitrile,[C]#[N],C#N +1837,NNitroso,[$(NN=O)],* +1838,PyridineRing,[$(n1ccccc1)],* +1839,TerminalTertButyl,[$([C]([CH3])([CH3])([CH3])([*]))],* +1840,TertiaryAmine,[!R&NX3&H0],* +1841,TriazineRing,"[$(n1nnccc1),$(n1ncncc1),$(n1cncnc1)]",* +1842,Trifluoromethyl,[$([*]C(F)(F)F)],* +1843,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1 +1844,Phenoxazines,"[OX1,N]=[#6]1-,:[#6]=,:[#6]2-,:[#16X2,#8X2]-,:[#6]3=,:[#6]-,:[#6](=,:[#6]-,:[#6]=,:[#6]3-,:[#7]=,:[#6]2-,:[#6]=,:[#6]1)",*=C1C=CC2=NC3=CC=CC=C3*C2=C1 +1845,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1 +1846,Imidazotriazoles,"[c,n]1cnn2c([NH])cnc12",[NH]c1cnc2*cnn12 +1847,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21 +1848,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21 +1849,NCCN,"[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]-[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]",** +1850,Picolylamines_A,"[$([NX3][CH2]c1ncnc([NX3])c1),$([NX3][CH2]c1nccc([NX3])n1)]",* +1851,Picolylamines_B,"[$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]n([H,CH3])cc1),$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]ccn1[H,CH3])]",* +1852,Picolylamines_C,"c1cccnc1[CH2!R][NX3!R]([H,CH3])[CH2!R]",*N([CH2])[CH2]c1ccccn1 +1853,Bis-picolylamines,"[nv3X2]c([c,s,n])[CX4][NX3]([H,C])[CX4]c([c,s,n])[nv3X2,nv3X3H1]",*N(Cc(*)*)Cc(*)n +1854,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1 +1855,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1 +1856,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n +1857,Diarylmethanes,"[$(c1[nX2][c,n][c,n][c,n]1),$([cr6][nX2r6])][CX4H2!R][$(c2[nX2][c,n][c,n][c,n]2),$([cr6][nX2r6])]",*[CH2]* +1858,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12 +1859,Heterylamides_A,"[$([cr5][n,s;r5][n,o;r5]),$([cr5]([nr5])[s,o,n;r5])][Nv3X3H1!R][CX3!R](=[OX1])[$([cr5][nv3X2r5]),$(c1ncccc1),$(c1c([OX2][CH3])cccc1)]",*[NH]C(*)=O +1860,Heterylamides_B,"[$(c1nnc[o,n]1),$(c1nccs1)][Nv3X3H!R][C!R](=[OX1])[CX4!H0]([H,CX4])[SX2,n]cc",*[NH]C(=O)C(*)*cc +1861,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1 +1862,8-Quinolinols,"[H,C][OX2]c1c([CX4][NX3])ccc2cccnc21",*Oc1c(CN)ccc2cccnc12 +1863,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1 +1864,Perchloroquinone,"[OX1]=[CX3]1C([F,Cl,Br,I])=C([F,Cl,Br,I])[CX3](=[OX1])C([F,Cl,Br,I])=C1[F,Cl,Br,I]",*C1=C(*)C(=O)C(*)=C(*)C1=O +1865,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn +1866,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1 +1867,A3,"[OH][CX3](=[OX1])[#6]1-,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:1",O=C([OH])C1=CC=CC=*1 +1868,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1 +1869,B5,"[#6]1=,:[#6]-,:[#6]=,:[#6]([OH])-,:[#6]2=,:[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]2",[OH]C1=CC=CC2=C1*=CC=C2 +1870,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12 +1871,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12 +1872,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12 +1873,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1 +1874,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1 +1875,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1 +1876,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1 +1877,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1 +1878,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1 +1879,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1 +1880,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12 +1881,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12 +1882,"C10, C11","[CH3]c1nc([OH])cc([OH,CH3])n1",*c1cc([OH])nc([CH3])n1 +1883,"C10*, C11*","[CX4]c1nc([OH])cc([OH,CX4])n1",*c1cc([OH])nc(C)n1 +1884,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH] +1885,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S +1886,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH] +1887,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH] +1888,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S +1889,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C +1890,"E6, E8","O=[#6]1-,:[#7]([H,CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",*N1C=CC=C([OH])C1=O +1891,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH] +1892,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C +1893,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S +1894,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S +1895,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH] +1896,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH] +1897,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH] +1898,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH] +1899,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1 +1900,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1 +1901,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1 +1902,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1 +1903,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1 +1904,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1 +1905,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21 +1906,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1 +1907,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12 +1908,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH] +1909,"G9,G10","c1ccc(c(c1)[OH,SH])[OX2][CX4]",*c1ccccc1OC +1910,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH] +1911,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH] +1912,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH] +1913,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH] +1914,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH] +1915,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1 +1916,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1 +1917,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1 +1918,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1 +1919,H8 - H12,"C[CX3](=[OX1])[CX4!H0]([H,CX4,Cl])[CX3](=[OX1])C",*C(C(C)=O)C(C)=O +1920,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O +1921,Salts_C,"[!#1!#2!#5!#6!#7!#8!#9!#10!#14!#15!#16!#17!#18!#32!#33!#34!#35!#36!#51!#52!#53!#54!#84!#85!#86]~[#6,#7,#8,#16]",*~* +1922,Pt,[Pt],[Pt] +1923,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +1924,β-lactones and γ- sultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +1925,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O +1926,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +1927,Heterocyclic Polycyclic Aromatic Hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +1928,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1929,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1 +1930,Azafluorenones,"[OX1,SX1]=[#6X3]1c2c([nX2][cX3,nX2,nX3][cX3,nX2,nX3][cX3,nX2,nX3]2)[c,n]2c1[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])]2",*=C1c2cccc*2c2n*:*:*c21 +1931,Cyanothioazinones,"[SX1]=[#6X3]1-,:[#7X3H1]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#7X2,#6X3!$([#6X3]=[A])]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#6X3]1([CX2]#[NX1])",N#CC1=**=*[NH]C1=S +1932,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1 +1933,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1934,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1 +1935,Benzoxathiolones,"[$([#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]),$([#8]1-,:[#6](-,:[#16]c4ccc(cc14)[#7,#8])=[OX1,SX1])]",* +1936,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21 +1937,Pyrazolones,"[#7X2]1=,:[#6X3]-,:[#6X3](-,:[#6X3](-,:[#7X3]1)=[SX1,OX1])=,:[#6X3H1](-,:[#7X3H1])",*=C1NN=CC1=[CH][NH] +1938,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1 +1939,Pyrimidinones_A,"[OX1,SX1]=[#6X3]1[#7X3](-,:[#7X2]=,:[#6X3][NX3H1][#6])-,:[cX3!$([#6X3]=[A])]=,:[#7X2]-,:[cX3!$([#6X3]=[A])]=,:[cX3!$([#6X3]=[A])]1",*=C1c=cN=cN1N=C[NH]C +1940,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12 +1941,Pyrimidinones_C,"[OX1,SX1]=[#6X3]1[#7X3]-,:[#6X3!$([#6X3]=[A])](-[NX3])=,:[#7X2]-,:[#6X3]2([nX2][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])]c12)",*=C1NC(N)=NC2nCCCc21 +1942,Pyrimidinodiones,"[#6X3]1(=[OX1,SX1])-,:[#7X3H1]-,:[#6X3](=[OX1,SX1])-,:[#7X3,#7X2]~[#6X3]([#7X2,#7X3;R1])-,:[#6X3]1[sX2r5R1,nX2r5R1,$([nx2r6R1]([cX3])[cX3])]",*C1C(*)C(=*)[NH]C(=*)*~1 +1943,Thienopyrimidinone_A,"[OX1,SX1]=[#6X3]1-,:[#7X3H1]-,:[#6X4]-,:[#7X3H1]-,:[#6]2-,:[#16X2,#8X2]-,:[#6]3[CX4][NX3,CX4][CX4][CX4]-,:[#6]3-,:[#6]12",*=C1[NH]C[NH]C2*C3C*CCC3C21 +1944,Piperazinediones,"[#7X3]1-,:[#6X3](=[OX1,SX1])-,:[#6X3](=[OX1,SX1])-,:[NX3]-,:[#6X3]2[cX3!$([#6X3]=[A])][cX3]([NX3H1][CX3]=[OX1])[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3]12",*=C1NC2cc([NH]C=O)ccc2NC1=* +1945,4-Heteryl-thiazoles,"s1[c,nX2][c,nX2](-c(c)[nX2,nX3,sX2])[nX2]c1",*c(c)-*1:*scn1 +1946,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1 +1947,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH] +1948,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1 +1949,Cyanothioethers,"[NX1]#[CX2][CX4H2][SX2]c1n[c,n][c,n][c,n]n1",N#C[CH2]Sc1n*:*:*n1 +1950,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1 +1951,Fused azacycles_A,"[nX2R1][c,n;R2]1[c,n;R2]([c,n;R1])[c,n][c,n][c,n;R2]([c,n;R1])[nR2]1[nX2R1]",*:*1:*:*:*(:*)n(n)*:1n +1952,Fused azacycles_B,"[NX1]#[CX2]c1[c!$([#6]=[OX1])]n[n,c!$([#6]=[OX1])]2[c,n][c!$([#6]=[OX1])][c!$([#6]=[OX1])]nc12",N#Cc1cn*2:*ccnc21 +1953,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12 +1954,Arylethanolamines,"[$([NX3]([CX4,H])([CX4,H])[CX4]),$([OX2]([H,CX4])[CX4])][CX4!H0][CX4H2][NX3H1]c[nX2r6R1][nX2,nX3][nX2,cX3;R1][cX3,nX2][cX3,nX2][sX2,cX3][cX3]",*C[CH2][NH]cn*:*:*:*:*c +1955,Azaspironones,"[X4;R2]12(-,:;@[#6X3]-,:;@[#6X3]-,:;@[#7X3]-,:;@[#6X3]-,:;@1)-,:;@[#16X2]-,:;@[#6X3]=,:;@[#7X2]-,:;@[#7X3]-,:;@2",C1C*2(CN1)NN=CS2 +1956,Radical,[#16;X3v3+0],S +1957,N⋯X halogen bonding,"N[F,Cl,Br,I]",*N +1958,Charged atoms,"[+,-]",* +1959,Benzyl Imidazole scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*-,=*c:3:c:c:c:c:c:3",*(*c1ccccc1)*1:*:*2:*c*c*:2:*:1 +1960,6-Phenyl Napthaline type scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s][c,n,o,s]2)*~*c:3:c:c:c:c:c:3",*(~*c1ccccc1)*1:*:*:*2:*c*c*:2:*:1 +1961,2-(2-(1H-pyrrol-2-yl)ethyl)-1H-benzoimidazole scaffold,"[c,n]:1:c:c2:c(:[c,n]:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*~*c3ccc*3",*(~*c1ccc*1)*1:*c2*c*cc2*:1 +1962,2 - Olefin group,"[$([CX3H2]=[CX3H1]),$([CX3H1]=[CX3H1]),$([CX3H2]=[CX3H0]),$([CX3H1]=[CX3H0]),$([CX3H0]=[CX3H0])]",* +1963,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +1964,6 - Methanol,[CX4H3][OX2H1],[CH3][OH] +1965,7 - Water,[OX2H2],O +1966,9 - Сarbonyl,"[$([CX4H3][CX3](=[OX1])[#6]),$([CX4H2][CX3H0](=[OX1])[#6])]",* +1967,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O +1968,11 - Acetate group,"[$([CX4H3][CX3](=[OX1])[OX2][#6]),$([CX4H2][CX3](=[OX1])[OX2][#6])]",* +1969,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +1970,14 - Primary amine,"[$([CX4H3][NX3H2]),$([CX4H2][NX3H2]),$([CX4H1][NX3H2])]",* +1971,16 - Tertiary amine,"[$([CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]),$([CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6])]",* +1972,19 - CCN,"[$([CX4H3][CX2]#[NX1]),$([CX4H2][CX2]#[NX1])]",* +1973,20 - COOH,"[$([CX3H0](=[OX1])[OX2H1]),$([CX3H1](=[OX1])[OX2H1])]",* +1974,21 - CCl,"[$([CX4H2!$([CX4H2](Cl)Cl)]Cl),$([CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl]),$([CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl])]",* +1975,22 - CCl2,"[$([CX4H2]([Cl])[Cl]),$([CX4H1]([!Cl!F])([Cl])[Cl]),$([CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F])]",* +1976,23 - CCl3,"[$([CX4H1]([Cl])([Cl])[Cl]),$([CX4H0]([!Cl!F])([Cl])([Cl])[Cl])]",* +1977,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +1978,26 - CNO2,"[$([CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)])]",* +1979,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S +1980,29 - CH3SH,"[$([CX4H3][SX2H1]),$([CX4H2][SX2H1])]",* +1981,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +1982,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +1983,32 - Iodo compounds,[I],I +1984,33 - Bromo compounds,[Br!$([Br][cR])],Br +1985,34 - Carbon triple bond,"[$([CX2H1]#[CX2H0]),$([CX2H0]#[CX2H0])]",* +1986,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +1987,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +1988,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl +1989,39 - DMF,"[$([CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3]),$([CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2])]",* +1990,40 - CF2,"[$([CX4](F)(F)(F)[!Cl!F]),$([CX4](F)(F)([!F!Cl!H])([!F!Cl!H])),$([CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]))]",* +1991,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +1992,42 - SiH2,"[$([SiX4H3]),$([SiX4H2]([!$([OX2])])([!$([OX2])])),$([SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])])),$([SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]))]",* +1993,43 - SiO,"[$([SiX4H2][OX2]),$([SiX4H1][OX2]),$([SiX4H0][OX2])]",* +1994,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +1995,47 - OCCOH,"[$([OX2H0!R][CX4H2][CX4H2][OX2H1]),$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +1996,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +1997,52 - Sulphones,"[$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2]),$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1])]",* +1998,53 - Oxides,"[$([CX4H2]1[OX2][CX4H2]1),$([CX4H2]1[OX2][CX4H1]1),$([CX4H2]1[OX2][CX4H0]1),$([CX4H1]1[OX2][CX4H1]1),$([CX4H1]1[OX2][CX4H0]1),$([CX4H0]1[OX2][CX4H0]1)]",* +1999,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2000,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C +2001,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH] +2002,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C +2003,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C +2004,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C +2005,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c +2006,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +2007,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH] +2008,17 - H2O (7 - Water),[OX2H2],O +2009,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O +2010,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O +2011,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O +2012,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O +2013,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O +2014,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +2015,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3] +2016,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2] +2017,28 - THF (13 - Ether),[OX2R!r3!$([OX2]C=[OX1])!$([OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1)]([R])[CX4H2R],*O[CH2] +2018,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2] +2019,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2] +2020,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2] +2021,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3] +2022,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2] +2023,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH] +2024,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3] +2025,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2] +2026,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1 +2027,39 - C5H4N (18 - Pyridine),"[$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]:[cX3H1]1)]",* +2028,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N +2029,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N +2030,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH] +2031,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH] +2032,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl +2033,46 - CHCl (21 - CCl),[CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl],*[CH](*)Cl +2034,47 - CCl (21 - CCl),[CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl],*C(*)(*)Cl +2035,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl +2036,49 - CHCl2 (22 - CCl2),[CX4H1]([!Cl!F])([Cl])[Cl],*[CH](Cl)Cl +2037,50 - CCl2 (22 - CCl2),[CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F],*C(*)(Cl)Cl +2038,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl +2039,52 - CCl3 (23 - CCl3),[CX4H0]([!Cl!F])([Cl])([Cl])[Cl],*C(Cl)(Cl)Cl +2040,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +2041,55 - CH3NO2 (26 - CNO2),"[CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH3] +2042,56 - CH2NO2 (26 - CNO2),"[CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH2] +2043,57 - CHNO2 (26 - CNO2),"[CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH] +2044,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S +2045,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH] +2046,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH] +2047,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +2048,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +2049,64 - I (32 - Iodo compounds),[I],I +2050,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br +2051,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C +2052,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C +2053,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +2054,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +2055,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl +2056,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O +2057,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O +2058,74 - CF3 (40 - CF2),[CX4](F)(F)(F)[!Cl!F],*C(F)(F)F +2059,75 - CF2 (40 - CF2),[CX4](F)(F)([!F!Cl!H])([!F!Cl!H]),*C(*)(F)F +2060,76 - CF (40 - CF2),[CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]),*C(*)(*)F +2061,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +2062,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3] +2063,79 - SiH2 (42 - SiH2),[SiX4H2]([!$([OX2])])([!$([OX2])]),*[SiH2]* +2064,80 - SiH (42 - SiH2),[SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[SiH](*)* +2065,81 - Si (42 - SiH2),[SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[Si](*)(*)* +2066,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2] +2067,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH] +2068,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si] +2069,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +2070,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl +2071,87 - CCl2F (45 - CClF),[CX4H0]([Cl])([Cl])([F])[!Cl!F],*C(F)(Cl)Cl +2072,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl +2073,89 - HCClF (45 - CClF),[CX4H1](Cl)(F)([!F!Cl]),*[CH](F)Cl +2074,90 - CClF2 (45 - CClF),[CX4H0](Cl)(F)(F)[!Cl!F],*C(F)(F)Cl +2075,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl +2076,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl +2077,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl +2078,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O +2079,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O +2080,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O +2081,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O +2082,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O +2083,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O +2084,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH] +2085,101 - C2H4O2 (47 - OCCOH),"[$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +2086,102 - CH3S (48 - CH2S),[CX4H3][SX2H0][*],*S[CH3] +2087,103 - CH2S (48 - CH2S),[CX4H2][SX2H0!$([SX2H0]([CX4H2])[CX4H3])][*],*S[CH2] +2088,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +2089,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1 +2090,107 - C4H3S (50 - Thiophene),"[$([#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H0]=,:1),$([#6X3H1]1-,:[#16X2]-,:[#6X3H0]=,:[#6X3H1]-,:[#6X3H1]=,:1)]",* +2091,109 - NCO (51 - NCO),[*][NX2]=[CX2]=[OX1],*N=C=O +2092,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O +2093,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O +2094,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1 +2095,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1 +2096,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1 +2097,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1 +2098,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1 +2099,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1 +2100,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2101,phosphorodithionate,[$([SX2H0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2102,"O,O-diethylphosphorodithionate",CCOP(=S)(OCC)SC([*:1]),CCOP(=S)(OCC)SC[*:1] +2103,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O +2104,"O,O-dimethylphosphoryl",COP(=O)(O([*:1]))OC,COP(=O)(OC)O[*:1] +2105,phosphorothionate,[$([OH0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2106,diethylphosphorothionate,CCOP(=S)(O([*:1]))OCC,CCOP(=S)(OCC)O[*:1] +2107,O-phenyl phenylphosphonothioate,S=P(O([*:1]))(Oc1ccc([*:1])cc1)c1ccccc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])c1ccccc1 +2108,O-phenyl phosphonothioate,S=P(O([*:1]))(O([*:1]))Oc1ccc([*:1])cc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])O[*:1] +2109,carbamate,[$(N([!H])C(=O)[OH0])]C(=O)[OH0],*C(O)=O +2110,"2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-(aminosulfanyl)-N-methylcarbamate",CN(SN([*:1])([*:1]))C(=O)Oc1cccc2CC(C)(C)Oc12,CN(SN([*:1])[*:1])C(=O)Oc1cccc2c1OC(C)(C)C2 +2111,methyl(propoxysulfanyl) carbamate,CN(SOCCC([*:1]))C(=O)O([*:1]),CN(SOCCC[*:1])C(=O)O[*:1] +2112,phenyl carbamate,O=C(N([*:1]))Oc1ccccc([*:1])1,O=C(N[*:1])Oc1ccccc1[*:1] +2113,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C +2114,dimethylcarbamate,CN(C)C(=O)O([*:1]),CN(C)C(=O)O[*:1] +2115,barbiturates,*C1(*)[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]1=O,*C1(*)C(=O)NC(=O)NC1=O +2116,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1 +2117,Phenothiazine,*-[#7]-1-c2ccccc2-[#16]-c2ccccc-12,*N1c2ccccc2Sc2ccccc21 +2118,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1 +2119,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1 +2120,"2,4-dichloro-benzene-1,3-dicarbonitrile",N#Cc1c([*:1])c([*:1])c(Cl)c(C#N)c1Cl,N#Cc1c(Cl)c(C#N)c([*:1])c([*:1])c1Cl +2121,R1 - Reactive alkyl halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2122,R2 - Acid halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2123,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O +2124,R4 - Sulphate esters,"COS(=O)O[C,c]",*OS(=O)OC +2125,R5 - Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2126,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O +2127,R7 - Peroxides,OO,OO +2128,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2129,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1 +2130,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O +2131,R11 - Isocyanates & Isothiocyanantes,"N=C=[S,O]",*=C=N +2132,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2133,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S +2134,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2135,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-] +2136,R16 - beta carbonyl quaternary Nitrogen,"C(=O)C[N+,n+]",*CC=O +2137,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O +2138,"R18 - Quaternary C,Cl,I,P or S","[C+,Cl+,I+,P+,S+]",* +2139,R19 - Phosphoranes,C=P,C=P +2140,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl +2141,R21 - Nitroso,[N&D2](=O),N=O +2142,R22 - P/S Halides,"[P,S][Cl,Br,F,I]",** +2143,R23 - Carbodiumide,N=C=N,N=C=N +2144,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+] +2145,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2146,R26 - Cyanohydrins,N#CC[OH],N#CC[OH] +2147,R27 - Acyl cyanides,N#CC(=O),N#CC=O +2148,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O +2149,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2150,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N +2151,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2152,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC +2153,I2 - Compounds with 4 or more acidic groups,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2154,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2155,I4 - Disulphides,SS,SS +2156,I5 - Thiols,[SH],[SH] +2157,"I6 - Epoxides, Thioepoxides, Aziridines","C1[O,S,N]C1",*1CC1 +2158,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2159,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2160,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2161,I10 - Thiocyanate,SC#N,N#CS +2162,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+] +2163,I12 - Thioesters,"C[O,S;R0][C;R0](=S)",C*C=S +2164,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N +2165,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1 +2166,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2167,I16 - Betalactams,N1CCC1=O,O=C1CCN1 +2168,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1 +2169,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2170,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2171,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2172,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2173,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2174,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1 +2175,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2176,"A1 - e.g., carboxylic acid","[OH1][P,C,S](=O)",O=*[OH] +2177,"A2 - e.g.,imide","[NH1]([P,S]=O)([P,S]=O)",O=*[NH]*=O +2178,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1 +2179,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1 +2180,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1 +2181,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O +2182,A8,[nH1]1ncoc1=O,O=c1[nH]nco1 +2183,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1 +2184,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1 +2185,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1 +2186,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1 +2187,A13,[nH1]1occc1=O,O=c1cco[nH]1 +2188,A14,[OH1]c1oncc1,[OH]c1ccno1 +2189,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1 +2190,A16 - tetrazole,[nH1]nnn,nnn[nH] +2191,A17,[nH1](n)nn,nn[nH]n +2192,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1 +2193,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1 +2194,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1 +2195,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1 +2196,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1 +2197,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1 +2198,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1 +2199,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21 +2200,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21 +2201,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21 +2202,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH] +2203,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1 +2204,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH] +2205,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F +2206,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O +2207,A33 - phenol,"[OH1]c1c[c,n]ccc1",[OH]c1c*ccc1 +2208,B1 - primary amine,[NH2][CX4],C[NH2] +2209,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C +2210,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C +2211,B4SUB,"[C,c](=N)N",N*=N +2212,B5EXC,"[C,c](=N)N[C,S](=O)",N=*N*=O +2213,B6,"[$([C,c](=N)N);!$([C,c](=N)N[C,S](=O))]",* +2214,B7EXC,n(:c)(:c):a,*n(c)c +2215,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1 +2216,B8EXC,"[N,n;+1]",* +2217,B9,"[$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]",* +2218,E1 - alkyl and aryl ketones and aldehydes,"[C;H1](=[O,S])[C,c]",*C=* +2219,"E2 - e.g., carboxylic esters","[C,P;H1](=[O,S])[O,S]",**=* +2220,"E3 - e.g., carbonates","[C](=O)([C,c,O,S])[C,c,O,S]",*C(*)=O +2221,E4EXC,C(=O)[OH1],O=C[OH] +2222,E5EXC,C(=O)[SH1],O=C[SH] +2223,E6,"C(=[O,S])(N)Oc",*=C(N)Oc +2224,"E7 - e.g., aryl carbamates","C1(=O)NS(=O)(=O)[C,c]=,:[C,c]1",O=C1*=*S(=O)(=O)N1 +2225,E8SUB,"P(=O)[O,S]",*P=O +2226,E9EXC,P[OH1],[OH]P +2227,E10,"[$(P(=O)[O,S]);!$(P[OH1])]",* +2228,E11,c(=O)(~c)~c,c~c(~c)=O +2229,E12EXC,"[$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)]",* +2230,E12,"[$(c(=O)(~c)~c);!$([$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)])]",* +2231,E13 - imides,C(=O)-N-C=O,O=CNC=O +2232,N1 - pimary amines,[NX3H2][CX4],C[NH2] +2233,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C +2234,N4EXC,"N=[O,C,N,S]",*=N +2235,N5EXC,"N-[C,c,N]=[C,c,N,n,O,S]",*=*N +2236,N6,"[OH1][C,c,N;!$(C=O)]",*[OH] +2237,N7EXC,[OH1]C=C,C=C[OH] +2238,N8EXC,"[OH1]NC=[O,S]",*=CN[OH] +2239,N9,"[$([NX3H2]!:c),$([NX3H1]([CX4])!:c),$([NX3H0]([CX4])([CX4])!:c)]",* +2240,NUC,"[$([NH2][CX4]),$([NH]([CX4])[CX4]),$([OH1][C,c,N;!$(C=O)]),$([$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]);!$(N=[O,C,N,S]);!$(N-[C,c,N]=[C,c,N,n,O,S]);!$([OH1]C=C);!$([OH1]NC=[O,S])]",* +2241,> 2 ester groups,"C(=O)O[C,H1].C(=O)O[C,H1].C(=O)O[C,H1]",*OC=O.*OC=O.*OC=O +2242,2-halo pyridine,"n1c([F,Cl,Br,I])cccc1",*c1ccccn1 +2243,Acid halide,"C(=O)[Cl,Br,I,F]",*C=O +2244,Acyclic C=C-O,C=[C!r]O,C=CO +2245,Acyl cyanide,N#CC(=O),N#CC=O +2246,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O +2247,Aliphatic long chain,[R0;D2][R0;D2][R0;D2][R0;D2],**** +2248,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1 +2249,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1 +2250,Azido group,N=[N+]=[N-],[N-]=[N+]=N +2251,Azo group,N=N,N=N +2252,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1 +2253,Benzidine,"[cR2]1[cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2][cR2]1[cR2]2[cR2][cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2]2",*c1ccc(c2ccc(*)cc2)cc1 +2254,Betaketo/anhydride,"[C,c](=O)[CX4,CR0X3,O][C,c](=O)",O=***=O +2255,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2256,Carbo cation/anion,"[C+,c+,C-,c-]",* +2257,Catechol,"c1c([OH])c([OH,NH2,NH])ccc1",*c1ccccc1[OH] +2258,Charged oxygen or sulfur atoms,"[O+,o+,S+,s+]",* +2259,Chinone (1),"C1(=[O,N])C=CC(=[O,N])C=C1",*=C1C=CC(=*)C=C1 +2260,Chinone (2),"C1(=[O,N])C(=[O,N])C=CC=C1",*=C1C=CC=CC1=* +2261,Conjugated nitrile group,C=[C!r]C#N,C=CC#N +2262,Crown ether,"[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]",*~C~C~*~C~C~* +2263,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1 +2264,Cyanamide,N[CH2]C#N,N[CH2]C#N +2265,Cyanate/aminonitrile/thiocyanate,"[N,O,S]C#N",*C#N +2266,Cyanohydrins,N#CC[OH],N#CC[OH] +2267,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1 +2268,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1 +2269,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1 +2270,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1 +2271,Diaminobenzene (1),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])c([N+R0,NX3R0,nX3R0])[cR2][cR2]1",*c1ccccc1* +2272,Diaminobenzene (2),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2]c([N+R0,NX3R0,nX3R0])[cR2]1",*c1cccc(*)c1 +2273,Diaminobenzene (3),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2][cR2]c1([N+R0,NX3R0,nX3R0])",*c1ccc(*)cc1 +2274,Diazo group,[N!R]=[N!R],N=N +2275,Diketo group,"[C,c](=O)[C,c](=O)",O=**=O +2276,Disulphide,SS,SS +2277,Enamine,[CX3R0][NX3R0],CN +2278,Ester of HOBT,C(=O)Onnn,nnnOC=O +2279,Four member lactones,C1(=O)OCC1,O=C1CCO1 +2280,Halogenated ring (1),"c1cc([Cl,Br,I,F])cc([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1ccc(*)c(*)c1 +2281,Halogenated ring (2),"c1ccc([Cl,Br,I,F])c([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1cccc(*)c1* +2282,Heavy metal,"[Hg,Fe,As,Sb,Zn,Se,se,Te,B,Si]",* +2283,Het-c-het not in ring,"[NX3R0,NX4R0,OR0,SX2R0][CX4][NX3R0,NX4R0,OR0,SX2R0]",*C* +2284,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1 +2285,Hydroxamic acid,C(=O)N[OH],O=CN[OH] +2286,Imine,C=[N!R],C=N +2287,Isolated alkene,"[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]=[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]",*=* +2288,Ketene,C=C=O,C=C=O +2289,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1 +2290,Michael acceptor (1),"C=!@CC=[O,S]",*=CC=C +2291,Michael acceptor (2),"[$([CH]),$(CC)]#CC(=O)[C,c]",*C(=O)C#* +2292,Michael acceptor (3),"[$([CH]),$(CC)]#CS(=O)(=O)[C,c]",*S(=O)(=O)C#* +2293,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O +2294,Michael acceptor (5),"[$([CH]),$(CC)]#CC(=O)O[C,c]",*OC(=O)C#* +2295,N oxide,"[NX4,nX3][OX1]",*O +2296,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1 +2297,N-c-halo,"NC[F,Cl,Br,I]",*CN +2298,N-halo,"[NX3,NX4][F,Cl,Br,I]",** +2299,N-hydroxylpyridine,n[OH],n[OH] +2300,Nitro group,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]",* +2301,N-nitroso,[#7]-N=O,NN=O +2302,Oxime (1),"[C,c]=N[OH]",*=N[OH] +2303,Oxime (2),"[C,c]=NOC=O",*=NOC=O +2304,Oxygen-nitrogen single bond,"[OR0,NR0][OR0,NR0]",** +2305,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F +2306,Peroxide,OO,OO +2307,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1 +2308,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1 +2309,Phosphor,P,P +2310,Phthalimide,"[cR,CR]~C(=O)NC(=O)~[cR,CR]",*~C(=O)NC(~*)=O +2311,Polycyclic aromatic hydrocarbon (1),"a1aa2a3a(a1)[a,A]=,:[a,A]-,:[a,A]=,:[a,A]3A=AA2",*1*=**2:*3:*1:*:*:*:*:3:*=**=2 +2312,Polycyclic aromatichydrocarbon (2),a21aa3a(aa1aaaa2)aaaa3,*1:*:*:*2:*:*3:*:*:*:*:*:3:*:*:2:*:1 +2313,Polycyclic aromatichydrocarbon (3),a31a(a2a(aa1)aaaa2)aaaa3,*1:*:*:*2:*(:*:1):*:*:*1:*:*:*:*:*:1:2 +2314,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C +2315,Quaternary nitrogen (1),"[s,S,c,C,n,N,o,O]~[nX3+,NX4+](~[s,S,c,C,n,N])~[s,S,c,C,n,N]",*~*(~*)~* +2316,Quaternary nitrogen (2),"[s,S,c,C,n,N,o,O]~[n+,N+](~[s,S,c,C,n,N,o,O])(~[s,S,c,C,n,N,o,O])~[s,S,c,C,n,N,o,O]",*~*(~*)(~*)~* +2317,Quaternary nitrogen (3),[*]=[N+]=[*],*=[N+]=* +2318,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2319,Silicon halogen,"[Si][F,Cl,Br,I]",*[Si] +2320,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1 +2321,Sulfinic acid,"[SX3](=O)[O-,OH]",*S=O +2322,Sulfonic acid,"[C,c]S(=O)(=O)O[C,c]",*OS(*)(=O)=O +2323,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2324,Sulfur oxygen single bond,[SX2]O,OS +2325,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-] +2326,Sulphur nitrogen single bond,[SX2H0][N],NS +2327,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1 +2328,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1 +2329,Thiocarbonyl group,"[C,c]=S",*=S +2330,Thiol (1),[S-],[SH-] +2331,Thiol (2),[SH],[SH] +2332,Three-membered heterocycle,"*1[O,S,N]*1",*1**1 +2333,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2334,Triphenyl methylsilyl,"[SiR0,CR0](c1ccccc1)(c2ccccc2)(c3ccccc3)",c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2335,Triple bond,C#C,C#C +2336,Aromatic NO2,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-c(:*):*",*c(:*):* +2337,Deuterium,[2H],[2HH] +2338,C13,[13#6],[13CH4] +2339,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1 +2340,"Si,B,Se atoms","[Si,B,Se]",* +2341,Hetero imides,[!#6]-[CH2]-N1C(=O)CCC(=O)1,*CN1C(=O)CCC1=O +2342,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O +2343,Acyclic imines,"C-!@[NX2]=[C!R,#1]-C",C*=NC +2344,Alkyl esters of S or P,"[S,P](=O)OC",CO*=O +2345,Ugly P compounds,"P(=[O,S])[C,N]([C,N])[C,N]",**(*)P=* +2346,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN +2347,Acyclic N-C-N,N-!@[CX4]-!@N,NCN +2348,Acyclic N-S,N-!@[SX2]-*,*SN +2349,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O +2350,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O +2351,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1 +2352,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O +2353,Acyl halide,"O=C-[F,Cl,Br,I]",*C=O +2354,Alpha halo carbonyl,"O=C-C-[F,Cl,Br,I]",*CC=O +2355,Sufonyl halide,"S(=O)(=O)-[F,Cl,Br,I]",*[SH](=O)=O +2356,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N +2357,26,N-C(=S)-N,NC(N)=S +2358,Terminal vinyl,[CH2D1]=[CD2]-!@*,*C=C +2359,28,S=P~*,*~P=S +2360,Thio cyanates,S-C#N,N#CS +2361,Thionyl,[Sv4](=O)(-!@[!#1])-!@[!#1],*S(*)=O +2362,N-Haloamines,"N-[F,Cl,Br,I]",*N +2363,N-C-Hal or cyano methyl,"N-C-[F,Cl,Br,I,$(C#N)]",*CN +2364,Alpha beta-unsaturated ketones; center of Michael reactivity,"[$(C#N),$(N(~O)~O),$(C=O),$(S(=O)=O),$(C(F)(F)F),Cl][C!H0]=[C!H0]",*C=C +2365,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O +2366,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2] +2367,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2] +2368,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N +2369,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO +2370,42,S-S,SS +2371,43,O~O,O~O +2372,Aziridine-like N in 3-membered ring,N~1~*~*1,*1~*~N~1 +2373,Aryl iodide,I-c:*,*:cI +2374,Aryl bromide,Br-c:*,*:cBr +2375,Multiple aromatic rings,a1aaa2a(a1)aaa(a2):a,*:*1:*:*:*2:*:*:*:*:*:2:*:1 +2376,S/PO3 groups,"[P,S](~O)(~O)~O",O~*(~O)~O +2377,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3 +2378,Too many cyano groups (>1),C#N.C#N,C#N.C#N +2379,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH] +2380,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O +2381,Chlorates,Cl~O,O~Cl +2382,High halogen content (>3),"[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I]",*.*.*.* +2383,Filter1_2_halo_ether,"[Cl,Br,I][CX4][CX4][$([O,S,N]*),Cl,Br,I]",*CC* +2384,Filter2_acyl_phosphyl_sulfonyl_halide,"[C,S,P](=O)[F,Cl,Br,I]",**=O +2385,Filter3_allyl_halide,"[F,Cl,Br,I][CX4]C=C",*CC=C +2386,Filter4_alpha_halo_carbonyl,"[Br,Cl,I][C!H0]C=[O,S]",*CC=* +2387,Filter5_azo,"[!#7,#1]~[NX2R0]=[NX2R0]~[!#7,#1]",*~N=N~* +2388,Filter6_benzyl_halide,"[Br,Cl,I][CX4]c",*Cc +2389,Filter7_diazo,[!#7]~[NX2]~[NX1],*~N~N +2390,Filter8_thio_isocyanat_diimin,"N=C=[N,O,P,S]",*=C=N +2391,Filter9_metal,"[!#1!#6!#7!#8!#9!#15!#16!#17]~[*,#1]",*~* +2392,Filter10_Terminal_vinyl,"[CH2]=[CH][N,O,P,S;R0]",*[CH]=C +2393,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O +2394,Filter12_nitroso,"[*,#1]~[NX2]~[OX1]",*~N~O +2395,Filter13_PS_double_bond,"S=P~[*,#1]",*~P=S +2396,Filter14_thio_oxopyrylium_salt,"c1ccc[s,o;X2]c1",*1ccccc1 +2397,Filter15_thiosulfate,[SX4](~S)(~O)(~O)~*,*~S(~O)(~O)~S +2398,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C +2399,Filter17_trialkyl_phosphin2,[PX4](~[!O!S])([#6])([#6])[#6],*~P(C)(C)C +2400,Filter18_oxime_ester,"[!#7,#1]C=NO[C,S,P](=O)*",*C=NO*(*)=O +2401,Filter19_hydroxyimide_ester,O=C[NX3](C=O)OC(=O)*,*C(=O)ON(C=O)C=O +2402,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN +2403,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH] +2404,Filter22_sulfonium_salt,*[SX3](*)*,*S(*)* +2405,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O +2406,Filter24_react_imide,"*C([F,Cl,Br,I,$(OS(=O)(=O)*)])=[NX2]*",*N=C(*)* +2407,Filter25_sulfonyl_halide,"*S(=O)(=O)[F,Cl,Br,I]",*S(*)(=O)=O +2408,Filter26_alkyl_halide,"AA[CH2][F,Cl,Br,I,$(OS(=O)(=O)*)]",**[CH2]* +2409,Filter27_anhydride,"*[C,S](=O)O[C,S](=O)*",**(=O)O*(*)=O +2410,Filter28_halo_pyrimidine,"c1nc(ncc1)[Br,I]",*c1ncccn1 +2411,Filter29_thioester,"CC(=[OX1,SX1,NH])[SX2][*,#1]",*SC(=*)C +2412,Filter30_beta_halo_carbonyl,"[#6,#1]C(=O)CC[Br,I]",*CCC(*)=O +2413,Filter31_SO_bond,"[*,#1][SX2R0]O[*,#1]",*OS* +2414,Filter32_OO_bond,"[*,#1][OR0]O[*,#1]",*OO* +2415,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3] +2416,Filter34_isotope,"[2#1,3#1,13C,14C,15N,125I,23F,22Na,32P,33P,35S,45Ca,57Co,103Ru,141Ce]",* +2417,Filter35_PP_bond,P-P,PP +2418,Filter36_SS_double_bond,S=S,S=S +2419,Filter37_silicate,[Si]~O,O~[SiH4] +2420,Filter38_aldehyde,O=[CH]*,*[CH]=O +2421,Filter39_imine,C[CR0]=[NR0][*!O],*N=CC +2422,Filter40_epoxide_aziridine,"C1C[N,S,O]1",*1CC1 +2423,Filter41_12_dicarbonyl,*C(=O)C(=O)*,*C(=O)C(*)=O +2424,Filter42_12_dicarbonyl_tautomer,[*!$(C[OH])]=C([OH])C(=O)*,*C(=O)C(=*)[OH] +2425,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O +2426,Filter44_michael_acceptor2,"[#6,#1,OH0][C!$(C1(=O)C=CC(=O)C=C1)](=O)C=[C!$(C[Nv3X3,OH])]",*C(=O)C=C +2427,Filter45_allyl_halide2,"[Br,Cl,I][CX4]C=[C,N,P]",*CC=* +2428,Filter46_nhalide,"N[F,Cl,Br,I]",*N +2429,Filter47_SO2F,O=S(=O)(*)F,*S(=O)(=O)F +2430,Filter48_FOSO,O=S(*)OF,*S(=O)OF +2431,Filter49_halogen,"[*,#1]~[F,Cl,Br,I]~[*,#1]",*~*~* +2432,Filter50_grignard,"C[Mg][F,Cl,Br,I]",*[Mg]C +2433,Filter51_PN3,N[PX3](N)N,NP(N)N +2434,Filter52_NC_haloamine,"NC[F,Cl,Br,I]",*CN +2435,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +2436,Filter56_SS_bond,S-S,SS +2437,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1 +2438,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1 +2439,Filter59_phoshorous_ylide,C=P,C=P +2440,Filter60_Acyclic_N-S,N!@[SX2],N~S +2441,Filter61_phosphor_halide_and_P_S_bond,"[#15]~[F,Cl,Br,I,#16]",*~P +2442,Filter62_oxo_thio_halide,"[O,S]~[Cl,Br,I]",*~* +2443,Filter63_polyaromatic,a1aaaa2ccc3ccccc3c12,*1:*:*c2*(:*:1)ccc1ccccc12 +2444,Filter64_halo_ketone_sulfone,"[#6][C,S](=[O,S])C[F,Cl,Br,I]",*C*(=*)C +2445,Filter65_alkyl_sulfonate,"[#6][P,S](~[OX1])(~[OX1])O[C!H0]",CO*(C)(~O)~O +2446,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F +2447,Filter67_S_or_O_C_triplebond_N,"[O,S]C#N",*C#N +2448,Filter68_anthracene_acridine,a1aaac2cc3ccccc3cc12,*1:*:*c2cc3ccccc3cc2*:1 +2449,Filter69_thio_carbonate,"[O,S]C(=[O,S])[O,S]",*C(*)=* +2450,Filter70_AlkylCN2,*(C#N)C#N,N#C*C#N +2451,Filter71_thio_anhydride,"*C(=[O,S])[O,S]C(=[O,S])*",*C(=*)*C(*)=* +2452,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH] +2453,Filter73_thio_ketone,CC(=S)C,CC(C)=S +2454,Filter74_thiol,*[SX2H],*[SH] +2455,Filter75_alkyl_Br_I,"[C!H0][Br,I]",*C +2456,Filter76_S_ester,CC(=S)O,CC(O)=S +2457,Filter77_alkyl_NO2,"[*!#7]~[#6]-,=CN(~O)(~O)",*~CCN(~O)~O +2458,Filter78_bicyclic_Imide,*~@C1C(=O)NC(=O)C(~@*)1,*~C1C(~*)C(=O)NC1=O +2459,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1 +2460,Filter80_Thioepoxide_aziridone,"[N,S]1[C,N,S][C,N,S]1",*1**1 +2461,Filter81_Thiocarbamate,"S!@C(=!@[O,S])!@[#7]",*=C(~N)~S +2462,Filter82_pyridinium,"[c,n]1[c,n][c,n][c,n][c,n]n(C)1",Cn1*:*:*:*:*1 +2463,Filter83_per_halo_chain,"[F,Cl,Br,I]C-,=;!@C([F,Cl,Br,I])-,=;!@C([F,Cl,Br,I])",*CC(*)C* +2464,Filter84_nitrogen_mustard,"[N,P,Se,S][C!H0]C[Br,Cl,I]",*CC* +2465,Filter85_keto_acrylonitrile,*C(=O)C(=!@[C!H0])C#N,*C(=O)C(=C)C#N +2466,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N +2467,Filter87_crowns,"[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[O,N]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@C",*C~C*C~C*C~C*C +2468,Filter88_ene_sulfone,[C!H0]=CS(=O)(=O)*,*S(=O)(=O)C=C +2469,Filter89_hydroxylamine,"[*!$(C=O)]!@N!@O[*,#1]",*~N~O* +2470,Filter90_N_double_bond_S,N=!@S,N=S +2471,Filter92_trityl,*(c1ccccc1)(c1ccccc1)(c1ccccc1),c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2472,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O +2473,Filter94_2_halo_pyridine,"c1nc(ccc1)[Br,I,Cl,F]",*c1ccccn1 +2474,Anhydride,C(=O)OC(=O),O=COC=O +2475,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1 +2476,Any carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2477,HOBT ester,C(=O)Onnn,nnnOC=O +2478,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-] +2479,Imine2,"[#6,#8,#16]-[CH1]=[NH1]",*C=N +2480,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N +2481,Cyanohydrin,N#CC[OH],N#CC[OH] +2482,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl +2483,P/S halide,"[P,S][F,Cl,Br,I]",** +2484,Quaternary,"[C+,Cl+,I+,P+,S+]",* +2485,Unacceptable atoms,[!#6;!#7;!#8;!#16;!#1;!#3;!#9;!#11;!#12;!#15;!#17;!#19;!#20;!#30;!#35],* +2486,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2487,b-Carbonyl quaternary nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2488,Benzylic quaternary nitrogen,cC[N+],cC[N+] +2489,Phosphorane,C=P,C=P +2490,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S +2491,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2492,Sulfonate,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2493,Heteroaryl sulfonate,"a-S(=O)(=O)-O[$([a&!#6]),$(c[a&!#6]),$(cc[a&!#6]),$(ccc[a&!#6]),$(cccc[a&!#6]),$(ccccc[a&!#6])]",*OS(*)(=O)=O +2494,Sulfate ester,"COS(=O)O[C,c]",*OS(=O)OC +2495,Polyacidic,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2496,Thiol,[SH],[SH] +2497,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1 +2498,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +2499,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2500,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2501,Allene,*=C=*,*=C=* +2502,Azide,"[$(*-[NX2-]-[NX2+]#[NX1]),$(*-[NX2]=[NX2+]=[NX1-]),$(N=N=N)]",* +2503,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O +2504,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2505,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH] +2506,Ester,[#6]-C(=O)O-[#6],COC(C)=O +2507,Imine 1,"[#6,#8,#16]-C(=[NH1])[#6,#8,#16]",*C(*)=N +2508,Imine 3,C=[NH],C=N +2509,Thioketone,CC(=S)C,CC(C)=S +2510,Thionoester,COC(=S)C,COC(C)=S +2511,Thioamide,CC(=S)N,CC(N)=S +2512,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC +2513,Long aliphatic chain,"[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]",******* +2514,Unbranched chain,"[$([A&D2]),$([A&D1])]!@[A&D2]!@[A&D2]!@[A&D2]!@[A&D2]!@[$([A&D2]),$([A&D1])]",*~*~*~*~*~* +2515,Dye 25,acC=&!@Cca,*cC=Cc* +2516,Isonitrile,[N+]#[C-],[C-]#[NH+] +2517,Thiocyanate,SC#N,N#CS +2518,Dye 16 (1),"c[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c +2519,Nitro aromatic 2+,"a-[$([NX3](=O)=O),$([NX3+](=O)[O-])].a-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",**.** +2520,Dye 29,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-caac-[$(N(C)C),$([NH]C),$([NH2])]",*c*:*c* +2521,Dye 1 (1),"c1cccc(C(=O)[C,c]([#7])=,:[C,c]([#7])C2(=O))c12",N*1=*(N)C(=O)c2ccccc2C1=O +2522,Dye 7,"N=C1[#6]:,=[#6]C(=[C,N])[#6]:,=[#6]1",*=C1C:CC(=N)C:C1 +2523,Dye 11,"*=,:[#6]C([#6]=,:*)[#6]=,:*",*=CC(C=*)C=* +2524,Dye 9,ac-*=&!@*-&!@C(=O)-&!@ca,*c*=*C(=O)c* +2525,Dye 32,"c1cccc2C(=O)C(C:,=*)C(=O)c12",*:CC1C(=O)c2ccccc2C1=O +2526,Dye 6,c12cccc(C(=O)C(ca)C(=O)3)c2c3ccc1,*cC1C(=O)c2cccc3cccc(c23)C1=O +2527,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1 +2528,Dye 2,OCccCO,OCccCO +2529,Dye 26,c1ccccc1-n2nnnc2[CH2]*,*[CH2]c1nnnn1-c1ccccc1 +2530,Perhalo_ketone,"O=CC(-[F,Cl,Br,I])([F,Cl,Br,I])-[F,Cl,Br,I]",*C(*)(*)C=O +2531,Beta halo carbonyl,"O=CCC[F,Cl,Br,I]",*CCC=O +2532,4-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[n]:[c,n]:[c,n]1",*c1*:*n*:*1 +2533,2-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[c,n]:[c,n]:[n]1",*c1*:*:*:*n1 +2534,Hetero_hetero,"*[N,S,O]-&!@[N,S,O][#6]",***C +2535,Disulfide,SS,SS +2536,Vinyl michael acceptor1,"[#6]-[CH1]=C-C(=O)[#6,#7,#8]",*C(=O)C=CC +2537,Vinyl michael acceptor2,"[CH2]=C-C(=O)[#6,#7,#8]",*C(=O)C=C +2538,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N +2539,Michael acceptor 6,"[#6,#7]-&!@[#6](=&!@[CH])-&!@C(=O)-&!@[C,N,O,S]",*C(=[CH])C(*)=O +2540,Alkynyl michael acceptor1,"[#6]-C#CC(=O)[#6,#7,#8]",*C(=O)C#CC +2541,Alkynyl michael acceptor2,"[CH1]#CC(=O)-[#6,#7,#8]",*C(=O)C#C +2542,Nitroalkane,"C[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*C +2543,Nitrate,"[#6]-O-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*OC +2544,Oxalyl,O=C-&!@C=O,O=CC=O +2545,Dipeptide,*-C(=O)-&!@[NH]-C-&!@C(=O)-&!@[NH]-*,*NC(=O)CNC(*)=O +2546,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-] +2547,Triphenylphosphine,a-P(-a)-a,*P(*)* +2548,Phosphoric acid,[OH]-P(=O)(-O)-*,*P(=O)(O)O +2549,Phosphoric ester,COP(=O)(-*)O,*P(O)(=O)OC +2550,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2551,Tri phosphoric esters,[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6],*P(=O)(OC)OC.*P(=O)(OC)OC.*P(=O)(OC)OC +2552,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O +2553,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12 +2554,Poly(azo(anthracene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1[c,n]c3:[c,n]:[c,n]:[c,n]:[c,n]:c3[c,n]2",*1:*:*c2*c3*:*:*:*c3*c2*:1 +2555,Poly(azo(phenanthrene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1:[c,n]:[c,n]:c3:[c,n]:[c,n]:[c,n]:[c,n]:c23",*1:*:*c2c(*:1)*:*c1*:*:*:*c12 +2556,Dye 31,a1aaac2ac3acac4aaac(c34)c12,*1:*:*c2c(*:1)*c1*c*c3*:*:*c2c31 +2557,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21 +2558,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O +2559,"Epoxide, aziridine, thioepoxide","C1[O,S,N]C1",*1CC1 +2560,Propiolactone,C1(=O)OCC1,O=C1CCO1 +2561,b-Lactam,N1CCC1=O,O=C1CCN1 +2562,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2563,Aromatic sulfonic ester,"[#6,#7]-S(=O)(=O)Oc",*S(=O)(=O)Oc +2564,Quinone,"[$([o,n]=c1ccc(=[o,n])cc1),$([O,N]=C1C=CC(=[O,N])C=C1),$([O,N]=C1[#6]:,=[#6]C(=[O,N])[#6]:,=[#6]1)]",* +2565,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2566,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2567,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2568,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1 +2569,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2570,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1 +2571,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2572,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2573,Acid_anhydrides,C(=O)OC(=O),O=COC=O +2574,Acid_halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2575,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1 +2576,Active_phosphate,"P(=S)([OH1,O$(O[#6])])([OH1,O$(O[#6])])[S,O]",*P(*)(*)=S +2577,Acyl_cyanide,C(=O)-C#N,N#CC=O +2578,Adjacent_ring_double_bonds,[*;R]=[*;R]=[*;R],*=*=* +2579,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F +2580,Alkyl_halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2581,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C +2582,Alpha_halo_carbonyl,"[C;!$(C[N])](=O)!@[C;h1,h2;H1,H2][F,Cl,Br,I]",*C~C=O +2583,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O +2584,Aminonitrile,NC#N,NC#N +2585,Any_carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2586,Aromatic_azides,"c[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*c +2587,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-] +2588,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2589,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1 +2590,B-carbonyl_quaternary_nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2591,Benzylic_quaternary_nitrogen,"cC[N+,NX4]",*Cc +2592,Beta-carbonyl_quaternary_nitrogen,"C(=O)C[N+,n+,NX4,nX4]",*CC=O +2593,Beta-fluoro-ethyl-on,"[C;H2$(CF),H1$(C(F)F)]!@[CH2][N,O]",*[CH2]~C +2594,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2595,Carbazides,"C(=O)[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*C=O +2596,CCl3-CHO_releasing,"C(Cl)(Cl)(Cl)C([O,S])[NX3]",*C(N)C(Cl)(Cl)Cl +2597,Conjugated_dithioether,SC(=[!r])S,*=C(S)S +2598,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1 +2599,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1 +2600,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1 +2601,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2602,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2603,Diacetylene,C#CC#C,C#CC#C +2604,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-] +2605,Diazonium_salt,[N+]#N,N#[NH+] +2606,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O +2607,Dinitrobenzene_1,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc1",*c1ccccc1* +2608,Dinitrobenzene_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])c1",*c1ccc(*)cc1 +2609,Dinitrobenzene_3,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1cccc(*)c1 +2610,Dithiocarbamate,NC(=S)S,NC(S)=S +2611,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1 +2612,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1 +2613,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS +2614,Enyne,C=!@CC#C,C#CC=C +2615,"Epoxides,_thioepoxides,_aziridines","C1[O,S,N]C1",*1CC1 +2616,Ester_of_HOBT,C(=O)Onnn,nnnOC=O +2617,Flavin,"c1cccc(NC(=NC(=[N,S,O])NC(=O)3)C3=N2)c12",*=C1NC(=O)C2=Nc3ccccc3NC2=N1 +2618,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2 +2619,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF +2620,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F +2621,Four_member_lactones,C1(=O)OCC1,O=C1CCO1 +2622,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN +2623,Geminal_dinitriles,N#CCC#N,N#CCC#N +2624,"Halo-pyridine, -diazoles and -triazoles","[Cl,Br,I]c1[c,n][c,n][c,n][c,n]n1",*c1*:*:*:*n1 +2625,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1 +2626,Imines_(not_ring),"[#6][CR0](=[NR0,OR0])[#6]",*=C(C)C +2627,Isocyanates_and_isothiocyanates,"N=C=[S,O]",*=C=N +2628,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S +2629,Michael_phenyl_ketone,c1ccccc1C(=O)C=!@CC(=O)!@*,*~C(=O)C=CC(=O)c1ccccc1 +2630,Nitrobenz-azadiazole_1,"c1ccc(n[o,s]n2)c2c1[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c1cccc2n*nc12 +2631,Nitrobenz-azadiazole_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc(n[o,s]n2)c2c1",*c1ccc2n*nc2c1 +2632,Nitrosamine,N-[N;X2](=O),NN=O +2633,Noname,"N1=C[S,NH1]C(=[C,N,P][C,N,O,P])C1(=O)",**=C1*C=NC1=O +2634,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-] +2635,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN +2636,Orthoester,C(O)(O)[OH],OC(O)[OH] +2637,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH] +2638,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1 +2639,P_or_S_halides,"[P,S][Cl,Br,F,I]",** +2640,P-aminoaryl_diazo,Nc1aaa(N!@=N)aa1,Nc1*:*:*(N~N):*:*1 +2641,PCP,PCP,PCP +2642,Paranitrophenyl_esters,"C(=O)Oc1ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1ccc(OC=O)cc1 +2643,Pentahalophenyl,"c1c([F,Cl])c([F,Cl])c([F,Cl])c([F,Cl])c1([F,Cl])",*c1cc(*)c(*)c(*)c1* +2644,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2645,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34 +2646,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1 +2647,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O +2648,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2649,Phosphorus_halide,"[S,P][F,Cl,Br,I]",** +2650,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2651,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc +2652,Polyines,CC#CC#CC,CC#CC#CC +2653,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1 +2654,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12 +2655,Polysulfide,*[SX2][SX2][SX2]*,*SSS* +2656,Sulphur_halide,"[#16][F,Cl,Br,I]",*S +2657,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34 +2658,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1 +2659,Reactive_carbonyls,"[C;!r](=[O,S])[S;!r]",*=CS +2660,Ring_triple_bond,"[C,c;R]#[C,c;R]",*#* +2661,S=N (not_ring),[S;R0]=[N;R0],N=S +2662,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O +2663,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2664,Sulphate_ester,"COS(=O)O[C,c]",*OS(=O)OC +2665,Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2666,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S +2667,Tetraazinane,C1NNC=NN1,C1NNC=NN1 +2668,Thioles_(not_aromatic),[!a][SX2;H1],*S +2669,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S +2670,Three_membered_heterocycle,"*1[O,S]*1",*1**1 +2671,Tri_pentavalent_S,"[#16v3,#16v5]",* +2672,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1 +2673,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1 +2674,Triphenylphosphines,P(c1aaaaa1)(c1aaaaa1)(c1aaaaa1),*1:*:*c(P(c2*:*:*:*:*2)c2*:*:*:*:*2)*:*:1 +2675,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1 +2676,Vinyl_halide,"[Cl,Br,I]C=[!O!R]",*C=* +2677,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O +2678,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O +2679,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1 +2680,Oxime,"[#6]C(=!@N[$(OC),$([OH])])[#6]",*N=C(C)C +2681,Hydrazone,[#6]C(=!@NNa)[#6],*NN=C(C)C +2682,Nitrosone_not_nitro,[$(N(~!@[#6])!@O);!$([N+]([O-])=O)],* +2683,Thiocarbonyl_group,C=S,C=S +2684,Enamine_like,C=[NH],C=N +2685,Analine,"c1ccccc1[NH2,NH3+]",*c1ccccc1 +2686,Acid_anhydrides_2,"[#6]C(=O)!@OC(=!@[N,O])[#6]",*=C(C)O~C(C)=O +2687,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F +2688,Triple_bond,[#6]C#[CH],CC#C +2689,Thiatetrazolidine,"[$(Sc1nnn[nH,n-]1),$(Sc1nn[nH,n-]n1)]",* +2690,Glycol,"[#6][O;R0][$(C([#6])[#6]),$([CH][#6]),$([CH2])][O;R0][#6]",CO*OC +2691,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O +2692,Formate_formide,"O=[CH][O,N][#6]",C*[CH]=O +2693,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1 +2694,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1 +2695,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1 +2696,Thiazolidinone,O=C1CSCN1,O=C1CSCN1 +2697,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1 +2698,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1 +2699,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1 +2700,Ethene,C=[CH2],C=C +2701,Cyclobutene,C1CC=C1,C1CC=C1 +2702,Poly_sub_atomatic,*!@c1c(!@*)c(!@*)c(!@*)c(!@*)c1,*~c1cc(~*)c(~*)c(~*)c1~* +2703,Isotopes,"[2#1,3#1,11C,11c,14C,14c,125I,32P,33P,35S]",* +2704,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C +2705,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-] +2706,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-] +2707,Sulphur atom (1),[SX2H1],[SH] +2708,Sulphur atom (2),"[$([SX2H0]);!$([S][#6X3,#7X2]);!$([S][CX4H0])]",* +2709,Sulphur atom (3),"[$([SX2H0][#6X3,#7X2]);!$([S](~[#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2710,Sulphur atom (4),[$([S][*D4H0]);$([SX2H0])],* +2711,Sulphur atom (5),"[$([SX2H0]([#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2712,Sulphur atom (6),[sX2r5],s +2713,Sulphur atom (7),[$([#16X3](=[OX1]));$([#16]);!$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2714,Sulphur atom (8),[$([#16X3](=[OX1]));$([#16]);$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2715,Aldehyde carbon atoms,[$([CX3H1](=O)[#6])],* +2716,Phosphor with double bonded sulphur,[$([PX4]);$([P]=[S])],* +2717,sp3 hybridized carbon atoms (1),[$([CX4]([#6X3])([#6X3])[#6X3]);!$([CH0])],* +2718,sp3 hybridized carbon atoms (2),"[$([CX4][N]);!$([CH0]);!$([C][N]([#6X3,#7X2])[#6X3,#7X2]);!$([C][N]=[#6X3]);!$([CX4][NX3][C]=[O])]",* +2719,sp3 hybridized carbon atoms (3),"[!$([CH0]);$([CX4]([#6X3])[#6X3]),$([CX4][#7]=[#6X3]),$([CX4]([#8])[#8]);!$([CX4]([#8])[#8][C]=[O])]",* +2720,sp3 hybridized carbon atoms (4),[$([CX4][S]);!$([CH0]);!$([C][S]=[O])],* +2721,sp3 hybridized carbon atoms (5),"[$([CX4][#6X3]~[#8]),$([CX4][#6X3](~[#7])~[#7]),$([CX4][#6X2]),$([CX4][CX3]=[CX3]-[#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3]);!$([CX4][#6X3](=[#8])-[#8]);!$([CX4][CX3]([CX3])=[CX3]-[#6X3])]",* +2722,sp3 hybridized carbon atoms (6),[$([CX4][O]);!$([CH0]);!$([C][O][C]=[O]);!$([CX4]1[O][C]1)],* +2723,sp3 hybridized carbon atoms (7),[$([CX4][#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3])],* +2724,sp3 hybridized carbon atoms (8),"[$([CX4][#7](~[#6X3,#7X2])~[#6X3,#7X2]);!$([CH0])]",* +2725,sp3 hybridized carbon atoms (9),[$([CX4][S](=[O])=[O]);!$([CH0])],* +2726,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C +2727,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C +2728,sp3 hybridized carbon atoms (12),[$([CX4][NX3H1][C]=[O]);!$([CH0])],* +2729,sp2 hybridized carbon atoms (1),"[$([CX3H2]);$([C]=[#6X3,#7X2]-[#6X3,#7X2])]",* +2730,sp2 hybridized carbon atoms (2),"[$([CX3H1]);$([C]=[#6X3,#7X2]-[#6X3,#7X2]);!$([C](-[#6X3,#7X2])=[#6X3,#7X2]-[#6X3,#7X2])]",* +2731,sp2 hybridized carbon atoms (3),[$([cH1]);$([c](:[#7]):[#7])],* +2732,sp2 hybridized carbon atoms (4),"[$([ch1]);!$([ch1]1:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]:[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]1);$([ch1]1:[c](-[NX3]):[c]:[c]:[c]:[c]1),$([c]1:[c]:[c]:[c](-[NX3]):[c]:[c]1)]",* +2733,sp2 hybridized carbon atoms (5),"[$([CX3]);$([CX3]=[CX3]);!$([CH0]);!$([CX3](-[#6X3,#7X2])=[CX3]);!$([CX3]=[CX3]-[#6X3,#7X2])]",* +2734,sp2 hybridized carbon atoms (6),[$([cH1]);$([c]:[#16])],* +2735,sp2 hybridized carbon atoms (7),"[$([ch1]);$([c]1:[c]:[c]:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]1),$([c]1:[c]:[c]:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1)]",* +2736,sp2 hybridized carbon atoms 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false, + "name": "lstm_input" + } + }, + { + "class_name": "LSTM", + "config": { + "name": "lstm", + "trainable": true, + "dtype": "float32", + "batch_input_shape": [ + null, + null, + 47 + ], + "return_sequences": true, + "return_state": false, + "go_backwards": false, + "stateful": false, + "unroll": false, + "time_major": false, + "units": 300, + "activation": "tanh", + "recurrent_activation": "sigmoid", + "use_bias": true, + "kernel_initializer": { + "class_name": "RandomNormal", + "config": { + "mean": 0.0, + "stddev": 0.05, + "seed": 71 + } + }, + "recurrent_initializer": { + "class_name": "Orthogonal", + "config": { + "gain": 1.0, + "seed": null + } + }, + "bias_initializer": { + "class_name": "Zeros", + "config": {} + }, + "unit_forget_bias": true, + "kernel_regularizer": null, + "recurrent_regularizer": null, + "bias_regularizer": null, + "activity_regularizer": null, + "kernel_constraint": null, + "recurrent_constraint": null, + "bias_constraint": null, + "dropout": 0.3, + "recurrent_dropout": 0.0, + "implementation": 2 + } + }, + { + "class_name": "LSTM", + "config": { + "name": "lstm_1", + "trainable": true, + "dtype": "float32", + "batch_input_shape": [ + null, + null, + 47 + ], + "return_sequences": true, + "return_state": false, + "go_backwards": false, + "stateful": false, + "unroll": false, + "time_major": false, + "units": 300, + "activation": "tanh", + "recurrent_activation": "sigmoid", + "use_bias": true, + "kernel_initializer": { + "class_name": "RandomNormal", + "config": { + "mean": 0.0, + "stddev": 0.05, + "seed": 71 + } + }, + "recurrent_initializer": { + "class_name": "Orthogonal", + "config": { + "gain": 1.0, + "seed": null + } + }, + "bias_initializer": { + "class_name": "Zeros", + "config": {} + }, + "unit_forget_bias": true, + "kernel_regularizer": null, + "recurrent_regularizer": null, + "bias_regularizer": null, + "activity_regularizer": null, + "kernel_constraint": null, + "recurrent_constraint": null, + "bias_constraint": null, + "dropout": 0.5, + "recurrent_dropout": 0.0, + "implementation": 2 + } + }, + { + "class_name": "Dense", + "config": { + "name": "dense", + "trainable": true, + "dtype": "float32", + "units": 47, + "activation": "softmax", + "use_bias": true, + "kernel_initializer": { + "class_name": "RandomNormal", + "config": { + "mean": 0.0, + "stddev": 0.05, + "seed": 71 + } + }, + "bias_initializer": { + "class_name": "Zeros", + "config": {} + }, + "kernel_regularizer": null, + "bias_regularizer": null, + "activity_regularizer": null, + "kernel_constraint": null, + "bias_constraint": null + } + } + ] + }, + "keras_version": "2.11.0", + "backend": "tensorflow" +} \ No newline at end of file diff --git a/Pre-Trained LSTM/No FSR/functions.csv b/Pre-Trained LSTM/No FSR/functions.csv new file mode 100644 index 0000000000000000000000000000000000000000..6083018652154fe92e56e4909d0ed2e5428e23ae --- /dev/null +++ b/Pre-Trained LSTM/No FSR/functions.csv @@ -0,0 +1,1246 @@ +,Len,Functional grp name,SMARTS,Smiles,Validity +0,7,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +1,8,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O,Valid +2,15,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1,Valid +3,5,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O,Valid +4,8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1,Valid +5,4,Thioesters,[CX3](=[SX1])[SX2],SC=S,Valid +6,13,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl,Valid +7,5,Epoxides,[CX4]1[CX4][OX2]1,C1CO1,Valid +8,12,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +9,13,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC,Valid +10,11,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1,Valid +11,18,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +12,16,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH],Valid +13,18,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1,Valid +14,16,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1,Valid +15,16,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1,Valid +16,14,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH],Valid +17,4,Thiols,[#16X2H1],[SH],Valid +18,7,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH],Valid +19,7,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S,Valid +20,3,Nitroso (general),[NX2]=[OX1],N=O,Valid +21,3,Azo-type (general),[NX2]=[NX2],N=N,Valid +22,5,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O,Valid +23,5,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1,Valid +24,8,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1,Valid +25,4,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N,Valid +26,32,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1,Valid +27,32,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1,Valid +28,11,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O,Valid +29,6,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O,Valid +30,8,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +31,11,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH],Valid +32,7,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +33,5,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O,Valid +34,2,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN,Valid +35,5,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O,Valid +36,6,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC,Valid +37,18,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +38,8,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O,Valid +39,10,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O,Valid +40,11,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O,Valid +41,8,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1,Valid +42,5,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O,Valid +43,5,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S,Valid +44,18,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1,Valid +45,7,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl,Valid +46,5,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1,Valid +47,7,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O,Valid +48,10,Primary alkyl amines,[CH2][NH2],[CH2][NH2],Valid +49,18,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3],Valid +50,20,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1,Valid +51,22,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +52,13,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1,Valid +53,19,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21,Valid +54,7,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +55,7,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC,Valid +56,4,Thiocyanates,[SX2][CX2]#[NX1],N#CS,Valid +57,21,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O,Valid +58,12,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O,Valid +59,6,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O,Valid +60,6,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C,Valid +61,6,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N,Valid +62,12,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C,Valid +63,7,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S,Valid +64,7,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S,Valid +65,2,Peroxides,[OX2][OX2],OO,Valid +66,2,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS,Valid +67,4,Nitroso,[#6][NX2]=[OX1],CN=O,Valid +68,4,N-Nitroso,[#7][NX2]=[OX1],NN=O,Valid +69,5,Azo,[#6][NX2]=[NX2][#6],CN=NC,Valid +70,5,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC,Valid +71,5,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C,Valid +72,6,Hydroxylamines,[OH1][NX3][#6],CN[OH],Valid +73,3,Aminals,N[CX4]N,NCN,Valid +74,12,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C,Valid +75,9,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C,Valid +76,9,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O,Valid +77,9,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O,Valid +78,9,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C,Valid +79,10,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O,Valid +80,6,Acrylonitriles,[NX1]#CC=C,C=CC#N,Valid +81,12,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O,Valid +82,14,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1,Valid +83,5,Ketenes,[CX3]=[CX2]=[OX1],C=C=O,Valid +84,5,Allenes,C=C=C,C=C=C,Valid +85,5,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1,Valid +86,5,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1,Valid +87,5,Aziridines,[CX4]1[NX3][CX4]1,C1CN1,Valid +88,6,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1,Valid +89,6,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1,Valid +90,6,Selen in chain,[Sev2X2],[SeH2],Valid +91,12,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O,Valid +92,12,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N,Valid +93,4,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O,Valid +94,7,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S,Valid +95,7,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S,Valid +96,7,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S,Valid +97,7,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S,Valid +98,11,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O,Valid +99,1,Positively charged N-heterocycles,[#7v4X3R],N,Valid +100,18,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH],Valid +101,20,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1,Valid +102,22,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1,Valid +103,25,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1,Valid +104,27,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1,Valid +105,18,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12,Valid +106,12,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl,Valid +107,12,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O,Valid +108,13,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC,Valid +109,13,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC,Valid +110,9,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O,Valid +111,6,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N,Valid +112,11,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C,Valid +113,10,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O,Valid +114,10,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C,Valid +115,12,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH],Valid +116,12,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C,Valid +117,9,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C,Valid +118,2,Iodine,II,II,Valid +119,8,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H],Valid +120,3,Sulfoxides,[Sv4X3](=[OX1]),O=S,Valid +121,2,Sulfenyl iodides,[SX2][IX1],SI,Valid +122,4,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS,Valid +123,8,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S,Valid +124,8,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS,Valid +125,7,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH],Valid +126,41,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1,Valid +127,5,Organotin compounds,[Sn][#6],C[Sn],Valid +128,8,β-Lactones,C1C(=O)OC1,O=C1CCO1,Valid +129,8,Thio-lactones,C1C(=O)SC1,O=C1CCS1,Valid +130,10,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC,Valid +131,26,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH],Valid +132,14,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1,Valid +133,11,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2],Valid +134,14,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1,Valid +135,11,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1,Valid +136,5,Sulfuranes,C1[SX2]C1,C1CS1,Valid +137,11,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1,Valid +138,12,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O,Valid +139,8,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O,Valid +140,16,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl,Valid +141,17,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C,Valid +142,18,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C,Valid +143,39,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH],Valid +144,19,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH],Valid +145,15,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1,Valid +146,30,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21,Valid +147,11,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O,Valid +148,24,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O,Valid +149,20,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1,Valid +150,7,Furans,c1ccc[oX2]1,c1ccoc1,Valid +151,7,Thiophenes,c1ccc[sX2]1,c1ccsc1,Valid +152,17,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O,Valid +153,10,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH],Valid +154,4,Thioles,[Sv2X2H1],[SH],Valid +155,8,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O,Valid +156,11,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH],Valid +157,1,Phosphorus,P,P,Valid +158,6,Selen,[Se],[SeH2],Valid +159,1,Bor,B,B,Valid +160,6,Silicium,[Si],[SiH4],Valid +161,3,Thione,[CX3]=[SX1!R],C=S,Valid +162,9,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH],Valid +163,7,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S,Valid +164,25,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2],Valid +165,12,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O,Valid +166,16,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1,Valid +167,16,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1,Valid +168,16,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1,Valid +169,16,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1,Valid +170,17,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1,Valid +171,6,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O,Valid +172,6,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N,Valid +173,16,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O,Valid +174,10,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N,Valid +175,12,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S,Valid +176,34,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12,Valid +177,40,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O,Valid +178,16,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH],Valid +179,2,N-N Single bound not in a ring,[N!R][N!R],NN,Valid +180,11,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC,Valid +181,10,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O,Valid +182,12,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1,Valid +183,15,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O,Valid +184,18,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3,Valid +185,18,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3,Valid +186,21,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1,Valid +187,18,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23,Valid +188,6,Cyano carbonyl compounds ,N#CC(=O),N#CC=O,Valid +189,5,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N,Valid +190,6,Benzyl ammoniums,cC[NX4+],cC[N+],Valid +191,8,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O,Valid +192,9,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N,Valid +193,7,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O,Valid +194,3,Singel acyclic N-N bonds,[#7]!@-N,N~N,Valid +195,11,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N,Valid +196,7,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O,Valid +197,2,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS,Valid +198,8,Phosphonates,[#6]P(=O)O[#6],COP(C)=O,Valid +199,16,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +200,14,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O,Valid +201,4,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS,Valid +202,13,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O,Valid +203,11,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F,Valid +204,4,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O,Valid +205,20,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1,Valid +206,15,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1,Valid +207,3,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC,Valid +208,4,Phosphocyanates,PC#N,N#CP,Valid +209,8,α-Hydroxy nitriles,N#CC[OH],N#CC[OH],Valid +210,6,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O,Valid +211,2,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO,Valid +212,11,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N,Valid +213,3,Nitroso compounds,[NX2]=O,N=O,Valid +214,19,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F,Valid +215,22,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12,Valid +216,17,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1,Valid +217,1,Phosphorus derivatives,[P!v5],P,Valid +218,12,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C,Valid +219,22,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1,Valid +220,18,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1,Valid +221,17,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1,Valid +222,17,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1,Valid +223,7,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O,Valid +224,15,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O,Valid +225,14,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1,Valid +226,6,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC,Valid +227,16,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH],Valid +228,18,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1,Valid +229,20,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21,Valid +230,14,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH],Valid +231,17,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1,Valid +232,15,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21,Valid +233,6,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c,Valid +234,11,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N,Valid +235,6,Phosphorus cations,[#15+],[PH4+],Valid +236,10,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O,Valid +237,3,Double P=O bonds,[#15]=O,O=P,Valid +238,5,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH],Valid +239,7,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +240,3,Nitrosos,[NX2]=[OX1],N=O,Valid +241,10,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F,Valid +242,7,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S,Valid +243,5,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH],Valid +244,12,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH],Valid +245,12,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH],Valid +246,5,Phenols,c[OH1],c[OH],Valid +247,3,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC,Valid +248,3,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc,Valid +249,3,Diarylethers,c[OX2&!$([OX2r3])]c,cOc,Valid +250,6,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid +251,6,Primary aromatic amines,[NX3H2]c,c[NH2],Valid +252,6,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C,Valid +253,6,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C,Valid +254,6,Secondary aromatic amines,[NX3H1](c)c,c[NH]c,Valid +255,6,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C,Valid +256,5,Organolithium compounds,[Li][#6],[Li]C,Valid +257,5,Organomagnesium compounds,[Mg][#6],C[Mg],Valid +258,7,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O,Valid +259,10,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O,Valid +260,7,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O,Valid +261,11,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH],Valid +262,9,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC,Valid +263,10,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH],Valid +264,13,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC,Valid +265,12,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O,Valid +266,11,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O,Valid +267,8,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O,Valid +268,7,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O,Valid +269,6,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH],Valid +270,4,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC,Valid +271,7,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C,Valid +272,5,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH],Valid +273,5,Thiophenols,c[Sv2H1],c[SH],Valid +274,13,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH],Valid +275,13,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH],Valid +276,6,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C,Valid +277,10,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O,Valid +278,12,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH],Valid +279,6,"Conjugated alkadienes (1,3-alkadienes)",[CX3]=[CX3][CX3]=[CX3],C=CC=C,Valid +280,7,"Unconjugated alkadienes (1,4-alkadienes)",[CX3]=[CX3][CX4][CX3]=[CX3],C=CCC=C,Valid +281,7,Alkynyl alcohols,[CX2]#[CX2][OH1],C#C[OH],Valid +282,7,Alkynyl thiols,[CX2]#[CX2][SH1],C#C[SH],Valid +283,21,phos_serine_warhead,NC(COP(O)(O)=O)C(O)=O,NC(COP(O)(O)=O)C(O)=O,Valid +284,24,phos_threonine_warhead,NC(C(C)OP(O)(O)=O)C(O)=O,CC(OP(O)(O)=O)C(N)C(O)=O,Valid +285,31,phos_tyrosine_warhead,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,NC(Cc1ccc(OP(O)(O)=O)cc1)C(O)=O,Valid +286,10,sulphonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +287,14,trifluoroacetate_thioester,C(F)(F)(F)C(=O)S,O=C(S)C(F)(F)F,Valid +288,5,hydroxamate_warhead,C([N;H1]([O;D1]))=O,ONC=O,Valid +289,12,thiol_warhead,NC(C[S;D1])C(O)=O,NC(CS)C(O)=O,Valid +290,6,acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +291,25,pentafluorophenylester,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +292,10,acyl_imidazole,"[C;!$(C-N)](=O)n1[c;H1,$([#6]([*;!R]))]n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1ccnc1,Valid +293,16,ortho_hydroiminoquinone,c1c([N;D1])c([N;D1])c[cH1][cH1]1,Nc1c[cH][cH]cc1N,Valid +294,3,phosphorus_phosphorus_bond,P~P,P~P,Valid +295,10,acyl_pyrazole,"[C;!$(C-N)](=O)n1n[c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))][c;H1,$(c([*;!R]))]1",O=Cn1cccn1,Valid +296,12,acyl_123_triazole,"[#7;R1]1=,:[#7;R1]-,:[#7;R1](-C(=O))-,:[#6]=,:[#6]1",O=CN1C=CN=N1,Valid +297,7,alpha_dicarbonyl,C(=O)!@C(=O),O=C~C=O,Valid +298,14,trifluoroacetate_ester,C(F)(F)(F)C(=O)O,OC(=O)C(F)(F)F,Valid +299,2,sulf_D2_nitrogen,[S;D2](-[N;!$(N(=C));!$(N(-S(=O)(=O)));!$(N(-C(=O)))]),NS,Valid +300,18,triflate,OS(=O)(=O)(C(F)(F)(F)),OS(=O)(=O)C(F)(F)F,Valid +301,15,rhodanine,C(=C)1SC(=S)NC(=O)1,C=C1SC(=S)NC1=O,Valid +302,5,NO_phosphonate,P(=O)ON,NOP=O,Valid +303,3,azo_filter3,[N;!R]-[N;!R]-[N;!R],NNN,Valid +304,30,disulfonyliminoquinone,S(=O)(=O)N=C1C=CC(=NS(=O)(=O))C=C1,O=S(=O)N=C1C=CC(=NS(=O)=O)C=C1,Valid +305,28,perchloro_cp,C1(Cl)(Cl)C(Cl)C(Cl)=C(Cl)C1(Cl),ClC1C(Cl)=C(Cl)C(Cl)C1(Cl)Cl,Valid +306,20,meldrums_acid_deriv,O=C1OC(C)(C)OC(C1)=O,CC1(C)OC(=O)CC(=O)O1,Valid +307,2,sulf_D2_oxygen_D2,[S;D2][O;D2],OS,Valid +308,3,azo_filter2,[N;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!r3;!$(N-S(=O)(=O));!$(N-C=O)]-[N;!$(N-S(=O)(=O));!$(N-C=O)],NNN,Valid +309,2,hydrazine,[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))]-[N;X3;!$(N-S(=O)(=O));!$(N-C(F)(F)(F));!$(N-C#N);!$(N-C(=O));!$(N-C(=S));!$(N-C(=N))],NN,Valid +310,10,isonitrile,[N+]#[C-],[C-]#[NH+],Valid +311,14,gte_3_COOH,C(=O)[O;D1].C(=O)[O;D1].C(=O)[O;D1],OC=O.OC=O.OC=O,Valid +312,3,phosphorus_sulfur_bond,P~S,P~S,Valid +313,9,polyene,C=[C;!R][C;!R]=[C;!R][C;!R]=[C;!R],C=CC=CC=C,Valid +314,4,azo_amino,[N]=[N;!R]-[N],N=NN,Valid +315,7,nitrone,[C;!R]=[N+][O;D1],C=[N+]O,Valid +316,1,sulfonium,[S+;X3;$(S-C);!$(S-[O;D1])],S,Valid +317,3,polysulfide,[S;D2]-[S;D2]-[S;D2],SSS,Valid +318,6,acrylate,[CH2]=[C;!$(C-N);!$(C-O)]C(=O),C=CC=O,Valid +319,15,four_nitriles,C#N.C#N.C#N.C#N,C#N.C#N.C#N.C#N,Valid +320,3,phosphorane,C=P,C=P,Valid +321,20,gte_7_aliphatic_OH,C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1].C[O;D1],CO.CO.CO.CO.CO.CO.CO,Valid +322,9,gte_2_free_phos,P([O;D1])=O.P([O;D1])=O,OP=O.OP=O,Valid +323,22,benzidine_like,c([N;!+])1ccc(c2ccc([N;!+])cc2)cc1,Nc1ccc(c2ccc(N)cc2)cc1,Valid +324,9,hydrazothiourea,[N;!R]=NC(=S)N,NC(=S)N=N,Valid +325,4,nitrosamine,N-[N;X2](=O),NN=O,Valid +326,10,gte_10_carbon_sb_chain,[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R]-[C;!R],CCCCCCCCCC,Valid +327,10,betalactam,C1(=O)~[#6]~[#6]N1,O=C1NC~C~1,Valid +328,3,peroxide,[#8]~[#8],O~O,Valid +329,18,paraquat_like,[#6]1[#6][#6]([#6]2[#6][#6][#7;+][#6][#6]2)[#6][#6][#7;+]1,C1CC(C2CCNCC2)CCN1,Valid +330,5,azo_aryl,c[N;!R;!+]=[N;!R;!+]-c,cN=Nc,Valid +331,2,disulfide_acyclic,[S;!R;X2]-[S;!R;X2],SS,Valid +332,5,gte_3_iodine,[#53].[#53].[#53],I.I.I,Valid +333,17,porphyrin,"[#6;r16,r17,r18]~[#6]1~[#6]~[#6]~[#6](~[#6])~[#7]1",C~C1N~C(~C)~C~C~1,Valid +334,7,thio_xanthate,[S;!R]-[C;!R](=[S;!R])(-[S;!R]),S=C(S)S,Valid +335,13,double_trouble_warhead,NC(C[S;D1])C([N;H1]([O;D1]))=O,NC(CS)C(=O)NO,Valid +336,13,Hzone_phenol_A,c1ccc(c(c1)[#8!H0])[#6]=[#7][#7],NN=Cc1ccccc1O,Valid +337,3,Azo_A,[N!R]=N,N=N,Valid +338,14,Mannich_A,N[CX4]c1c([OH1])cccc1,NCc1ccccc1[OH],Valid +339,15,Ene_rhod_A,N1C(=S)SC(=C)C1=O,C=C1SC(=S)NC1=O,Valid +340,18,Hzone_phenol_B,c1(ccc(cc1)C=N[#7])[OH1],NN=Cc1ccc([OH])cc1,Valid +341,20,Imine_one_isatin,[OX1]=C2C(=;!@N[#7])c3c(cccc3)N2,NN=C1C(=O)Nc2ccccc21,Valid +342,18,Anil_di_alk_B,c1c(ccc(c1)[#6]=[#6])[#7]([CX4])[CX4],CN(C)c1ccc(C=C)cc1,Valid +343,16,Catechol_A,c1ccc(c(c1)[OH1])[OH1],[OH]c1ccccc1[OH],Valid +344,21,Ene_five_one_A,c2ccc1C(=[OX1])C(=C)C(=[OX1])c1c2,C=C1C(=O)c2ccccc2C1=O,Valid +345,12,Ene_five_het_B,C1(=C)C(N=CS1)=O,C=C1SC=NC1=O,Valid +346,15,Ene_five_het_D,C1(=C)C(=[OX1])NNC1=[OX1],C=C1C(=O)NNC1=O,Valid +347,27,Ene_five_het_F,c1(ccccc1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)S2,O=C1C(=Cc2ccccc2)Sc2ccccc21,Valid +348,20,Ene_one_ester,[#6][#6](=[#8])[#6!H0]=[#6]([#7!H0][#6])[#6](=[#8])[#8][#6],CNC(=CC(C)=O)C(=O)OC,Valid +349,18,Ene_one_D,c([OH1])c-C(=[OX1])[C!H0]=C([#6])[#6],CC(C)=CC(=O)cc[OH],Valid +350,19,Ene_cyano_A,[#6](C#[#7])(C#[#7])=Cc1ccccc1,N#CC(=Cc1ccccc1)C#N,Valid +351,21,Hzone_pyrrol,n1(C)[cH1][cH1][cH1]c1C=NN,Cn1[cH][cH][cH]c1C=NN,Valid +352,45,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2,C=NNC(=O)c1[cH]c2[cH][cH][cH][cH]c2[cH]c1[OH],Valid +353,19,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1,O=C1CC(=O)c2ccccc21,Valid +354,22,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1],N#CC=C([NH2])C(C#N)C#N,Valid +355,20,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1,N#CC(C#N)=NNc1ccccc1,Valid +356,20,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9,C1C=CC2C1CNc1ccccc12,Valid +357,21,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7],Nc1c2ccccc2nc2ccccc12,Valid +358,13,Thiophene_hydroxy,"[#16]1-,:[#6]=,:[#6]-,:[#6](=,:[#6]1)[OH1]",[OH]C1=CSC=C1,Valid +359,25,Sulfonamide_B,c1c(ccc(c1)[NH]S(=[OX1])=[OX1])[OH1],O=S(=O)[NH]c1ccc([OH])cc1,Valid +360,7,Thio_ketone,"[#6]-,:[CX3](=[SX1])-,:[#6]",CC(C)=S,Valid +361,13,Rhod_sat_A,"[#7]1-,:[#6](=[#16])-,:[#16]-,:[#6X4]-,:[#6]1=[#8]",O=C1CSC(=S)N1,Valid +362,20,Imine_one_sixes,C1(C(=[OX1])NC(=[OX1])NC1(=[OX1]))=N,N=C1C(=O)NC(=O)NC1=O,Valid +363,22,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1,Valid +364,21,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1,Valid +365,21,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH],Valid +366,34,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +367,46,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH],Valid +368,31,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH],Valid +369,31,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1,Valid +370,51,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1,Valid +371,25,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH],Valid +372,36,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1,Valid +373,14,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1,Valid +374,27,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2,Valid +375,72,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1,Valid +376,39,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12,Valid +377,24,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC,Valid +378,27,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1,Valid +379,40,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1,Valid +380,32,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH],Valid +381,45,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12,Valid +382,38,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1,Valid +383,21,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2],Valid +384,39,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1,Valid +385,27,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12,Valid +386,31,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1,Valid +387,34,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12,Valid +388,52,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1,Valid +389,25,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1,Valid +390,30,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1,Valid +391,18,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1,Valid +392,46,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1,Valid +393,18,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1,Valid +394,22,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1,Valid +395,34,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2,Valid +396,18,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1,Valid +397,46,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +398,39,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1,Valid +399,32,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1,Valid +400,34,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12,Valid +401,17,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1,Valid +402,29,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O,Valid +403,21,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12,Valid +404,29,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21,Valid +405,48,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1,Valid +406,48,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1,Valid +407,22,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1,Valid +408,38,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc,Valid +409,34,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1,Valid +410,45,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1,Valid +411,19,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3,Valid +412,33,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21,Valid +413,22,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21,Valid +414,28,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12,Valid +415,18,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1,Valid +416,14,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1,Valid +417,20,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc,Valid +418,13,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1,Valid +419,26,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1,Valid +420,42,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1,Valid +421,18,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1,Valid +422,41,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21,Valid +423,48,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12,Valid +424,52,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21,Valid +425,10,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1,Valid +426,22,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1,Valid +427,16,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2,Valid +428,19,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc,Valid +429,44,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1,Valid +430,24,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21,Valid +431,26,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2,Valid +432,29,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21,Valid +433,30,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc,Valid +434,33,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21,Valid +435,15,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN,Valid +436,15,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S,Valid +437,12,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N,Valid +438,65,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1,Valid +439,25,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1,Valid +440,12,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S,Valid +441,23,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S,Valid +442,24,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1,Valid +443,47,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1,Valid +444,16,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O,Valid +445,17,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S,Valid +446,15,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1,Valid +447,41,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O,Valid +448,19,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1,Valid +449,31,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N,Valid +450,28,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21,Valid +451,21,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N,Valid +452,39,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2],Valid +453,48,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1,Valid +454,19,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N,Valid +455,27,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N,Valid +456,24,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc,Valid +457,16,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O,Valid +458,14,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O,Valid +459,19,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O,Valid +460,22,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12,Valid +461,23,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc,Valid +462,25,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1,Valid +463,15,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C,Valid +464,15,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1,Valid +465,18,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1,Valid +466,29,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O,Valid +467,33,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1,Valid +468,24,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1,Valid +469,28,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1,Valid +470,10,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1,Valid +471,22,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1,Valid +472,26,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1,Valid +473,25,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1,Valid +474,18,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S,Valid +475,18,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12,Valid +476,44,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1,Valid +477,52,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1,Valid +478,19,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2,Valid +479,22,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1,Valid +480,11,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1,Valid +481,22,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N,Valid +482,20,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12,Valid +483,27,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C,Valid +484,30,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N,Valid +485,28,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1,Valid +486,32,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH],Valid +487,23,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc,Valid +488,33,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12,Valid +489,35,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1,Valid +490,13,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1,Valid +491,20,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O,Valid +492,10,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH],Valid +493,27,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O,Valid +494,20,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21,Valid +495,20,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1,Valid +496,50,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21,Valid +497,42,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21,Valid +498,33,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1,Valid +499,13,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O,Valid +500,22,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O,Valid +501,21,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1,Valid +502,30,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O,Valid +503,11,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C,Valid +504,20,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1,Valid +505,20,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1,Valid +506,16,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21,Valid +507,11,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C,Valid +508,17,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O,Valid +509,15,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH],Valid +510,22,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S,Valid +511,24,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1,Valid +512,34,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1,Valid +513,32,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21,Valid +514,36,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O,Valid +515,24,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1,Valid +516,15,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1,Valid +517,29,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2],Valid +518,40,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1,Valid +519,26,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1,Valid +520,15,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc,Valid +521,25,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1,Valid +522,54,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1,Valid +523,34,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1,Valid +524,22,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc,Valid +525,12,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1,Valid +526,24,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1,Valid +527,24,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O,Valid +528,26,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1,Valid +529,18,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1,Valid +530,46,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1,Valid +531,26,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1,Valid +532,26,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3,Valid +533,25,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1,Valid +534,16,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N,Valid +535,28,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1,Valid +536,36,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O,Valid +537,38,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1,Valid +538,25,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1,Valid +539,38,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1,Valid +540,72,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2,Valid +541,56,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1,Valid +542,40,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1,Valid +543,20,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23,Valid +544,22,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2,Valid +545,35,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F,Valid +546,27,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2,Valid +547,35,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O,Valid +548,21,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1,Valid +549,38,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1,Valid +550,28,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1,Valid +551,32,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O,Valid +552,36,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1,Valid +553,29,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O,Valid +554,32,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O,Valid +555,61,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1,Valid +556,87,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH],Valid +557,27,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH],Valid +558,57,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1,Valid +559,59,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3],Valid +560,49,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1,Valid +561,49,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1,Valid +562,40,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH],Valid +563,23,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH],Valid +564,35,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1,Valid +565,39,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1,Valid +566,25,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1,Valid +567,81,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1,Valid +568,22,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1,Valid +569,31,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH],Valid +570,5,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1,Valid +571,5,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1,Valid +572,5,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1,Valid +573,6,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1,Valid +574,6,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1,Valid +575,6,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1,Valid +576,6,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1,Valid +577,5,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1,Valid +578,5,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1,Valid +579,5,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1,Valid +580,5,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1,Valid +581,6,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1,Valid +582,6,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1,Valid +583,6,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1,Valid +584,6,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1,Valid +585,5,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1,Valid +586,5,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1,Valid +587,5,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1,Valid +588,5,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1,Valid +589,5,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1,Valid +590,5,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1,Valid +591,5,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1,Valid +592,6,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1,Valid +593,6,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1,Valid +594,6,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1,Valid +595,6,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1,Valid +596,6,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1,Valid +597,6,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1,Valid +598,7,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1,Valid +599,7,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1,Valid +600,8,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1,Valid +601,7,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1,Valid +602,7,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1,Valid +603,6,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1,Valid +604,6,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1,Valid +605,6,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1,Valid +606,6,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1,Valid +607,6,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1,Valid +608,6,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1,Valid +609,7,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1,Valid +610,7,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1,Valid +611,7,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1,Valid +612,7,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1,Valid +613,7,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1,Valid +614,8,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1,Valid +615,8,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1,Valid +616,8,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1,Valid +617,8,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1,Valid +618,8,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1,Valid +619,8,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1,Valid +620,8,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1,Valid +621,7,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1,Valid +622,7,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1,Valid +623,7,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1,Valid +624,13,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1,Valid +625,13,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1,Valid +626,13,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1,Valid +627,7,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1,Valid +628,7,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1,Valid +629,7,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1,Valid +630,7,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1,Valid +631,7,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1,Valid +632,7,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1,Valid +633,8,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1,Valid +634,8,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1,Valid +635,8,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1,Valid +636,8,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1,Valid +637,8,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1,Valid +638,8,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1,Valid +639,8,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1,Valid +640,8,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1,Valid +641,8,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1,Valid +642,7,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1,Valid +643,7,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1,Valid +644,7,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1,Valid +645,7,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1,Valid +646,7,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1,Valid +647,7,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1,Valid +648,7,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1,Valid +649,7,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1,Valid +650,7,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1,Valid +651,7,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1,Valid +652,7,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1,Valid +653,7,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1,Valid +654,8,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1,Valid +655,8,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1,Valid +656,7,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1,Valid +657,7,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1,Valid +658,7,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1,Valid +659,7,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1,Valid +660,7,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1,Valid +661,7,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1,Valid +662,7,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1,Valid +663,7,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1,Valid +664,7,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1,Valid +665,7,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1,Valid +666,7,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1,Valid +667,7,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1,Valid +668,7,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1,Valid +669,7,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1,Valid +670,7,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1,Valid +671,7,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1,Valid +672,7,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1,Valid +673,7,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1,Valid +674,8,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1,Valid +675,8,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1,Valid +676,8,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1,Valid +677,9,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1,Valid +678,9,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1,Valid +679,8,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1,Valid +680,8,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1,Valid +681,8,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1,Valid +682,8,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1,Valid +683,8,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1,Valid +684,8,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1,Valid +685,8,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1,Valid +686,8,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1,Valid +687,8,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1,Valid +688,5,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C,Valid +689,5,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF,Valid +690,6,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl,Valid +691,6,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr,Valid +692,5,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI,Valid +693,4,Vinyl fluorides,F[CX3]=[CX3],C=CF,Valid +694,5,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl,Valid +695,5,Vinyl bromides,Br[CX3]=[CX3],C=CBr,Valid +696,4,Vinyl iodides,I[CX3]=[CX3],C=CI,Valid +697,4,Alkynyl fluorides,F[CX2]#[CX2],C#CF,Valid +698,5,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl,Valid +699,4,Alkynyl iodides,I[CX2]#[CX2],C#CI,Valid +700,5,Alkynyl bromides,Br[CX2]#[CX2],C#CBr,Valid +701,3,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC,Valid +702,3,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc,Valid +703,3,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc,Valid +704,10,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH],Valid +705,10,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH],Valid +706,5,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C,Valid +707,5,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C,Valid +708,7,Aldehyde,[CX3H1](=O)[#6],C[CH]=O,Valid +709,3,Formaldehyde,[CX3H2](=O),C=O,Valid +710,7,Ketone,[C][C](=O)[C],CC(C)=O,Valid +711,3,Nitrile,[C]#[N],C#N,Valid +712,27,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1,Valid +713,42,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1,Valid +714,19,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21,Valid +715,17,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21,Valid +716,14,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1,Valid +717,10,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1,Valid +718,14,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n,Valid +719,21,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12,Valid +720,21,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1,Valid +721,16,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1,Valid +722,10,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn,Valid +723,17,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1,Valid +724,18,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1,Valid +725,18,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12,Valid +726,18,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12,Valid +727,23,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12,Valid +728,26,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1,Valid +729,18,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1,Valid +730,18,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1,Valid +731,26,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1,Valid +732,18,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1,Valid +733,25,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1,Valid +734,21,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1,Valid +735,21,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12,Valid +736,18,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12,Valid +737,16,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH],Valid +738,16,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S,Valid +739,16,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH],Valid +740,16,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH],Valid +741,16,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S,Valid +742,22,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C,Valid +743,16,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH],Valid +744,22,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C,Valid +745,23,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S,Valid +746,19,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S,Valid +747,21,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH],Valid +748,22,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH],Valid +749,14,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH],Valid +750,11,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH],Valid +751,19,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1,Valid +752,16,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1,Valid +753,24,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1,Valid +754,21,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1,Valid +755,20,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1,Valid +756,11,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1,Valid +757,27,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21,Valid +758,30,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1,Valid +759,22,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12,Valid +760,16,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH],Valid +761,18,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH],Valid +762,22,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH],Valid +763,22,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH],Valid +764,28,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH],Valid +765,27,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH],Valid +766,25,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1,Valid +767,25,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1,Valid +768,29,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1,Valid +769,25,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1,Valid +770,13,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O,Valid +771,4,Pt,[Pt],[Pt],Valid +772,7,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O,Valid +773,9,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O,Valid +774,34,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N,Valid +775,28,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1,Valid +776,51,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1,Valid +777,46,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1,Valid +778,33,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1,Valid +779,36,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21,Valid +780,11,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1,Valid +781,32,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12,Valid +782,35,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1,Valid +783,18,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH],Valid +784,21,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1,Valid +785,32,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1,Valid +786,19,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12,Valid +787,1,Radical,[#16;X3v3+0],S,Valid +788,4,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +789,9,6 - Methanol,[CX4H3][OX2H1],[CH3][OH],Valid +790,1,7 - Water,[OX2H2],O,Valid +791,7,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O,Valid +792,8,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +793,13,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +794,5,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S,Valid +795,15,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +796,18,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +797,1,32 - Iodo compounds,[I],I,Valid +798,2,33 - Bromo compounds,[Br!$([Br][cR])],Br,Valid +799,15,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +800,9,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +801,5,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl,Valid +802,8,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +803,26,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +804,27,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +805,7,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +806,6,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C,Valid +807,9,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH],Valid +808,3,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C,Valid +809,6,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C,Valid +810,3,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C,Valid +811,5,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c,Valid +812,4,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH],Valid +813,9,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH],Valid +814,1,17 - H2O (7 - Water),[OX2H2],O,Valid +815,11,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O,Valid +816,11,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O,Valid +817,7,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O,Valid +818,12,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O,Valid +819,12,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O,Valid +820,8,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O,Valid +821,7,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3],Valid +822,7,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2],Valid +823,10,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2],Valid +824,10,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2],Valid +825,9,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2],Valid +826,10,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3],Valid +827,10,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2],Valid +828,9,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH],Valid +829,10,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3],Valid +830,10,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2],Valid +831,23,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1,Valid +832,8,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N,Valid +833,8,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N,Valid +834,7,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH],Valid +835,10,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH],Valid +836,7,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl,Valid +837,9,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl,Valid +838,12,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl,Valid +839,13,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl,Valid +840,5,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S,Valid +841,9,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH],Valid +842,9,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH],Valid +843,15,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1,Valid +844,18,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH],Valid +845,1,64 - I (32 - Iodo compounds),[I],I,Valid +846,2,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br,Valid +847,3,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C,Valid +848,3,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C,Valid +849,15,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O,Valid +850,9,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N,Valid +851,5,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl,Valid +852,19,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O,Valid +853,19,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O,Valid +854,8,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O,Valid +855,6,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3],Valid +856,7,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2],Valid +857,6,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH],Valid +858,5,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si],Valid +859,26,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O,Valid +860,12,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl,Valid +861,11,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl,Valid +862,10,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl,Valid +863,10,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl,Valid +864,11,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl,Valid +865,8,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O,Valid +866,12,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O,Valid +867,12,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O,Valid +868,16,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O,Valid +869,16,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O,Valid +870,16,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O,Valid +871,15,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH],Valid +872,27,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1,Valid +873,21,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1,Valid +874,19,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O,Valid +875,18,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O,Valid +876,13,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1,Valid +877,12,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1,Valid +878,9,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1,Valid +879,11,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1,Valid +880,8,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1,Valid +881,5,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1,Valid +882,7,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O,Valid +883,10,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O,Valid +884,11,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C,Valid +885,35,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1,Valid +886,11,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1,Valid +887,18,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1,Valid +888,14,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O,Valid +889,7,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O,Valid +890,2,R7 - Peroxides,OO,OO,Valid +891,25,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +892,21,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1,Valid +893,7,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O,Valid +894,18,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +895,7,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S,Valid +896,10,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +897,12,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-],Valid +898,5,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O,Valid +899,3,R19 - Phosphoranes,C=P,C=P,Valid +900,8,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +901,3,R21 - Nitroso,[N&D2](=O),N=O,Valid +902,5,R23 - Carbodiumide,N=C=N,N=C=N,Valid +903,10,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +904,13,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +905,8,R26 - Cyanohydrins,N#CC[OH],N#CC[OH],Valid +906,6,R27 - Acyl cyanides,N#CC(=O),N#CC=O,Valid +907,10,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O,Valid +908,16,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +909,6,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N,Valid +910,7,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +911,7,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC,Valid +912,7,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +913,2,I4 - Disulphides,SS,SS,Valid +914,4,I5 - Thiols,[SH],[SH],Valid +915,17,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +916,18,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +917,9,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +918,4,I10 - Thiocyanate,SC#N,N#CS,Valid +919,6,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+],Valid +920,9,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N,Valid +921,8,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1,Valid +922,19,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +923,8,I16 - Betalactams,N1CCC1=O,O=C1CCN1,Valid +924,16,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1,Valid +925,12,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +926,25,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +927,15,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +928,14,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +929,17,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +930,55,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1,Valid +931,14,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +932,13,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1,Valid +933,13,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1,Valid +934,20,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1,Valid +935,17,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O,Valid +936,12,A8,[nH1]1ncoc1=O,O=c1[nH]nco1,Valid +937,13,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1,Valid +938,15,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1,Valid +939,16,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1,Valid +940,13,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1,Valid +941,12,A13,[nH1]1occc1=O,O=c1cco[nH]1,Valid +942,11,A14,[OH1]c1oncc1,[OH]c1ccno1,Valid +943,12,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1,Valid +944,7,A16 - tetrazole,[nH1]nnn,nnn[nH],Valid +945,7,A17,[nH1](n)nn,nn[nH]n,Valid +946,16,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1,Valid +947,16,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1,Valid +948,18,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1,Valid +949,18,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1,Valid +950,16,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1,Valid +951,16,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1,Valid +952,16,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1,Valid +953,26,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21,Valid +954,26,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21,Valid +955,22,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21,Valid +956,16,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH],Valid +957,13,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1,Valid +958,8,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH],Valid +959,21,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F,Valid +960,12,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O,Valid +961,6,B1 - primary amine,[NH2][CX4],C[NH2],Valid +962,6,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C,Valid +963,6,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C,Valid +964,8,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1,Valid +965,7,E4EXC,C(=O)[OH1],O=C[OH],Valid +966,7,E5EXC,C(=O)[SH1],O=C[SH],Valid +967,5,E9EXC,P[OH1],[OH]P,Valid +968,9,E11,c(=O)(~c)~c,c~c(~c)=O,Valid +969,7,E13 - imides,C(=O)-N-C=O,O=CNC=O,Valid +970,6,N1 - pimary amines,[NX3H2][CX4],C[NH2],Valid +971,6,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C,Valid +972,7,N7EXC,[OH1]C=C,C=C[OH],Valid +973,4,Acyclic C=C-O,C=[C!r]O,C=CO,Valid +974,6,Acyl cyanide,N#CC(=O),N#CC=O,Valid +975,9,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O,Valid +976,13,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1,Valid +977,33,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1,Valid +978,11,Azido group,N=[N+]=[N-],[N-]=[N+]=N,Valid +979,3,Azo group,N=N,N=N,Valid +980,38,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1,Valid +981,14,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +982,6,Conjugated nitrile group,C=[C!r]C#N,C=CC#N,Valid +983,16,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1,Valid +984,9,Cyanamide,N[CH2]C#N,N[CH2]C#N,Valid +985,8,Cyanohydrins,N#CC[OH],N#CC[OH],Valid +986,9,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1,Valid +987,9,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1,Valid +988,10,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1,Valid +989,10,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1,Valid +990,3,Diazo group,[N!R]=[N!R],N=N,Valid +991,2,Disulphide,SS,SS,Valid +992,2,Enamine,[CX3R0][NX3R0],CN,Valid +993,7,Ester of HOBT,C(=O)Onnn,nnnOC=O,Valid +994,8,Four member lactones,C1(=O)OCC1,O=C1CCO1,Valid +995,13,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1,Valid +996,8,Hydroxamic acid,C(=O)N[OH],O=CN[OH],Valid +997,3,Imine,C=[N!R],C=N,Valid +998,5,Ketene,C=C=O,C=C=O,Valid +999,10,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1,Valid +1000,11,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O,Valid +1001,14,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1,Valid +1002,5,N-hydroxylpyridine,n[OH],n[OH],Valid +1003,4,N-nitroso,[#7]-N=O,NN=O,Valid +1004,10,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F,Valid +1005,2,Peroxide,OO,OO,Valid +1006,15,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1,Valid +1007,15,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1,Valid +1008,1,Phosphor,P,P,Valid +1009,6,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C,Valid +1010,25,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1011,21,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1,Valid +1012,10,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1013,2,Sulfur oxygen single bond,[SX2]O,OS,Valid +1014,14,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-],Valid +1015,2,Sulphur nitrogen single bond,[SX2H0][N],NS,Valid +1016,15,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1,Valid +1017,15,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1,Valid +1018,5,Thiol (1),[S-],[SH-],Valid +1019,4,Thiol (2),[SH],[SH],Valid +1020,18,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F,Valid +1021,3,Triple bond,C#C,C#C,Valid +1022,5,Deuterium,[2H],[2HH],Valid +1023,7,C13,[13#6],[13CH4],Valid +1024,10,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1,Valid +1025,23,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O,Valid +1026,2,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN,Valid +1027,3,Acyclic N-C-N,N-!@[CX4]-!@N,NCN,Valid +1028,6,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O,Valid +1029,27,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O,Valid +1030,20,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1,Valid +1031,7,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O,Valid +1032,9,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N,Valid +1033,7,26,N-C(=S)-N,NC(N)=S,Valid +1034,4,Thio cyanates,S-C#N,N#CS,Valid +1035,11,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O,Valid +1036,12,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2],Valid +1037,30,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2],Valid +1038,3,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N,Valid +1039,2,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO,Valid +1040,2,42,S-S,SS,Valid +1041,3,43,O~O,O~O,Valid +1042,18,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3,Valid +1043,7,Too many cyano groups (>1),C#N.C#N,C#N.C#N,Valid +1044,15,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH],Valid +1045,12,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O,Valid +1046,4,Chlorates,Cl~O,O~Cl,Valid +1047,5,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O,Valid +1048,6,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C,Valid +1049,2,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN,Valid +1050,8,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH],Valid +1051,14,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O,Valid +1052,50,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3],Valid +1053,2,Filter35_PP_bond,P-P,PP,Valid +1054,3,Filter36_SS_double_bond,S=S,S=S,Valid +1055,8,Filter37_silicate,[Si]~O,O~[SiH4],Valid +1056,6,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O,Valid +1057,6,Filter51_PN3,N[PX3](N)N,NP(N)N,Valid +1058,16,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1,Valid +1059,2,Filter56_SS_bond,S-S,SS,Valid +1060,15,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1,Valid +1061,15,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1,Valid +1062,3,Filter59_phoshorous_ylide,C=P,C=P,Valid +1063,3,Filter60_Acyclic_N-S,N!@[SX2],N~S,Valid +1064,24,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F,Valid +1065,14,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH],Valid +1066,7,Filter73_thio_ketone,CC(=S)C,CC(C)=S,Valid +1067,7,Filter76_S_ester,CC(=S)O,CC(O)=S,Valid +1068,20,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1,Valid +1069,4,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N,Valid +1070,3,Filter90_N_double_bond_S,N=!@S,N=S,Valid +1071,12,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O,Valid +1072,7,Anhydride,C(=O)OC(=O),O=COC=O,Valid +1073,26,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1,Valid +1074,7,HOBT ester,C(=O)Onnn,nnnOC=O,Valid +1075,12,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-],Valid +1076,6,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N,Valid +1077,8,Cyanohydrin,N#CC[OH],N#CC[OH],Valid +1078,8,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl,Valid +1079,13,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O,Valid +1080,6,Benzylic quaternary nitrogen,cC[N+],cC[N+],Valid +1081,3,Phosphorane,C=P,C=P,Valid +1082,7,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S,Valid +1083,16,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC,Valid +1084,4,Thiol,[SH],[SH],Valid +1085,20,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1,Valid +1086,18,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1,Valid +1087,17,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1088,18,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1089,7,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1090,9,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N,Valid +1091,13,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH],Valid +1092,8,Ester,[#6]-C(=O)O-[#6],COC(C)=O,Valid +1093,3,Imine 3,C=[NH],C=N,Valid +1094,7,Thioketone,CC(=S)C,CC(C)=S,Valid +1095,8,Thionoester,COC(=S)C,COC(C)=S,Valid +1096,7,Thioamide,CC(=S)N,CC(N)=S,Valid +1097,6,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC,Valid +1098,10,Isonitrile,[N+]#[C-],[C-]#[NH+],Valid +1099,4,Thiocyanate,SC#N,N#CS,Valid +1100,21,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1,Valid +1101,6,Dye 2,OCccCO,OCccCO,Valid +1102,2,Disulfide,SS,SS,Valid +1103,11,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N,Valid +1104,6,Oxalyl,O=C-&!@C=O,O=CC=O,Valid +1105,15,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-],Valid +1106,19,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1107,10,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O,Valid +1108,18,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12,Valid +1109,26,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21,Valid +1110,28,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O,Valid +1111,8,Propiolactone,C1(=O)OCC1,O=C1CCO1,Valid +1112,8,b-Lactam,N1CCC1=O,O=C1CCN1,Valid +1113,14,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1,Valid +1114,25,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1,Valid +1115,17,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1,Valid +1116,14,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2,Valid +1117,57,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1,Valid +1118,15,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21,Valid +1119,28,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1,Valid +1120,17,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH],Valid +1121,18,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH],Valid +1122,7,Acid_anhydrides,C(=O)OC(=O),O=COC=O,Valid +1123,20,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1,Valid +1124,6,Acyl_cyanide,C(=O)-C#N,N#CC=O,Valid +1125,19,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F,Valid +1126,12,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C,Valid +1127,28,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O,Valid +1128,4,Aminonitrile,NC#N,NC#N,Valid +1129,13,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-],Valid +1130,7,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O,Valid +1131,21,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1,Valid +1132,14,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1,Valid +1133,14,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1,Valid +1134,17,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1,Valid +1135,20,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1,Valid +1136,7,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO,Valid +1137,19,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH],Valid +1138,6,Diacetylene,C#CC#C,C#CC#C,Valid +1139,11,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-],Valid +1140,7,Diazonium_salt,[N+]#N,N#[NH+],Valid +1141,15,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O,Valid +1142,7,Dithiocarbamate,NC(=S)S,NC(S)=S,Valid +1143,10,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1,Valid +1144,10,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1,Valid +1145,3,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS,Valid +1146,6,Enyne,C=!@CC#C,C#CC=C,Valid +1147,7,Ester_of_HOBT,C(=O)Onnn,nnnOC=O,Valid +1148,30,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2,Valid +1149,8,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF,Valid +1150,10,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F,Valid +1151,8,Four_member_lactones,C1(=O)OCC1,O=C1CCO1,Valid +1152,3,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN,Valid +1153,7,Geminal_dinitriles,N#CCC#N,N#CCC#N,Valid +1154,14,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1,Valid +1155,7,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S,Valid +1156,4,Nitrosamine,N-[N;X2](=O),NN=O,Valid +1157,8,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-],Valid +1158,3,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN,Valid +1159,9,Orthoester,C(O)(O)[OH],OC(O)[OH],Valid +1160,20,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH],Valid +1161,13,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1,Valid +1162,3,PCP,PCP,PCP,Valid +1163,25,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F,Valid +1164,26,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1165,13,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1,Valid +1166,12,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O,Valid +1167,10,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O,Valid +1168,12,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C,Valid +1169,11,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc,Valid +1170,8,Polyines,CC#CC#CC,CC#CC#CC,Valid +1171,20,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1,Valid +1172,22,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12,Valid +1173,26,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34,Valid +1174,11,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1,Valid +1175,3,S=N (not_ring),[S;R0]=[N;R0],N=S,Valid +1176,9,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O,Valid +1177,10,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O,Valid +1178,3,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S,Valid +1179,9,Tetraazinane,C1NNC=NN1,C1NNC=NN1,Valid +1180,14,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S,Valid +1181,15,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1,Valid +1182,29,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1,Valid +1183,32,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1,Valid +1184,17,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O,Valid +1185,11,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O,Valid +1186,14,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1,Valid +1187,3,Thiocarbonyl_group,C=S,C=S,Valid +1188,3,Enamine_like,C=[NH],C=N,Valid +1189,14,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F,Valid +1190,4,Triple_bond,[#6]C#[CH],CC#C,Valid +1191,15,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O,Valid +1192,12,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1,Valid +1193,17,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1,Valid +1194,8,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1,Valid +1195,9,Thiazolidinone,O=C1CSCN1,O=C1CSCN1,Valid +1196,14,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1,Valid +1197,12,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1,Valid +1198,15,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1,Valid +1199,3,Ethene,C=[CH2],C=C,Valid +1200,7,Cyclobutene,C1CC=C1,C1CC=C1,Valid +1201,1,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C,Valid +1202,17,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-],Valid +1203,21,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-],Valid +1204,4,Sulphur atom (1),[SX2H1],[SH],Valid +1205,1,Sulphur atom (6),[sX2r5],s,Valid +1206,1,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C,Valid +1207,1,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C,Valid +1208,1,Nitrogen atoms (7),[nr5H0],n,Valid +1209,27,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21,Valid +1210,16,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C,Valid +1211,25,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1,Valid +1212,24,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1,Valid +1213,31,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1,Valid +1214,25,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1,Valid +1215,24,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1,Valid +1216,27,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1,Valid +1217,27,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1,Valid +1218,20,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1,Valid +1219,19,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1,Valid +1220,19,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1,Valid +1221,23,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1,Valid +1222,22,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2,Valid +1223,22,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC,Valid +1224,21,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1,Valid +1225,16,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1,Valid +1226,27,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1227,32,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1,Valid +1228,34,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1,Valid +1229,20,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1,Valid +1230,20,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1,Valid +1231,16,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1,Valid +1232,22,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1,Valid +1233,22,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12,Valid +1234,21,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1,Valid +1235,14,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1,Valid +1236,17,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1,Valid +1237,17,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1,Valid +1238,32,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1,Valid +1239,20,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1,Valid +1240,12,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2,Valid +1241,11,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2,Valid +1242,19,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1,Valid +1243,15,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2,Valid +1244,6,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2],Valid diff --git a/Pre-Trained LSTM/No FSR/vocab.csv b/Pre-Trained LSTM/No FSR/vocab.csv new file mode 100644 index 0000000000000000000000000000000000000000..a8d112ae53e12daec50e4a32374afc22776e5794 --- /dev/null +++ b/Pre-Trained LSTM/No FSR/vocab.csv @@ -0,0 +1,2787 @@ +,Functional grp name,SMARTS,Smiles +0,Acid halides,"[F,Cl,Br][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +1,Acid azides,"[CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C=O +2,Sulphonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[Cl,Br]",*S(C)(=O)=O +3,Sulphonyl azides,"[Sv6X4](=[OX1])(=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",*S(=O)=O +4,Acid anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +5,Diacyl peroxides,[CX3](=[OX1])[OX2][OX2][CX3](=[OX1]),O=COOC=O +6,Phenyl esters,[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][cR1][cR1]1,CC(=O)Oc1ccccc1 +7,Isocyanates,[NX2]=[CX2]=[OX1],N=C=O +8,β-Lactams,[NX3]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCN1 +9,Thioesters,[CX3](=[SX1])[SX2],SC=S +10,Haloalkanes,"[CX4][Cl,Br,I]",*C +11,Dialkylsulfates/ sulfonates,"[$([#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6]),$([#6][Sv6X4](=[OX1])(=[OX1])[OX2][#6])]",* +12,N-Trihalomethyl imides,"[CX3](=[OX1])[NX3]([CX4]([Cl,Br,I])([Cl,Br,I])[Cl,Br,I])[CX3](=[OX1])",*C(*)(*)N(C=O)C=O +13,Quinones,"[$([#6X3]1=,:[#6X3]-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]1(=[OX1])),$([#6X3]1(=[OX1])-,:[#6X3](=[OX1])-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1)]",* +14,Hydroquinones and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1][cR1][cR1]([OX2][#1,CX4])[cR1][cR1]1",*Oc1ccc(O*)cc1 +15,Catechols and O-alkyl precursors,"[#1,CX4][OX2][cR1]1[cR1]([OX2][#1,CX4])[cR1][cR1][cR1][cR1]1",*Oc1ccccc1O* +16,"α, β-Unsaturated aldehydes, amides, esters and ketones","[$([CX3]([#6,$([NX3]([CX3]=[OX1])([#6])[#6]),$([OX2]([CX3]=[OX1])[#6]);!$([OH][CX3]=[OX1]);!$([O-][CX3]=[OX1])])(=[OX1])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX3H1](=[OX1])[CX3]([#6,#1])=[CX3])]",* +17,"Precursors of α, β-unsaturated aldehydes, amides, esters and ketones (1)","[$([CX4]([OX2])([OX2])([#6,#7,#8])[CX3]([#6,#1])=[CX3]([!a])([!a])),$([CX4H1]([OX2])([OX2])[CX3]([#6,#1])=[CX3])]",* +18,"1,3-Diketones","[CX4,a!r0][CX3](=[OX1])[CH2][CX3](=[OX1])[CX4,a!r0]",*C(=O)[CH2]C(*)=O +19,Aldehydes,"[CX3]([H])(=[OX1])[#1,CX4,a!r0]",*C([H])=O +20,Ketones,"[CX4,a!r0][CX3](=[OX1])[CX4,a!r0]",*C(*)=O +21,Formaldehyde donors,"[$([NX3][CH2][NX3]),$([NX3][CH2][OX2]),$([CX4]([F,Cl,Br,I])([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])[CH2][OH1])]",* +22,Precursors of aldehydes and ketones,"[CX4]([OX2])([OX2])([CX4,a!r0])[CX4,a!r0]",*C(*)(O)O +23,Enol precursor of aldehydes and ketones,"[CX3]=[CX3]([#6,#1])[OX2]",*C(=C)O +24,Aromatic primary and secondary amines,"[a!r0][$([NX3H2]),$([NX3H1][CX4,a!r0])]",** +25,N-Haloimides,"[CX3](=[OX1])[NX3]([Cl,Br])[CX3](=[OX1])",*N(C=O)C=O +26,N-Chloro-sulfonamides,[Sv6X4](=[OX1])(=[OX1])[NX3H1]Cl,O=S(=O)[NH]Cl +27,Disullides,"[CX4,a!r0][SX2][SX2][CX4,a!r0]",*SS* +28,Phenyl carbonates,"c1ccccc1[OX2][CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)Oc1ccccc1 +29,Epoxides,[CX4]1[CX4][OX2]1,C1CO1 +30,1.2-Dicarbonyls,"[CX4,a!r0][CX3](=[OX1])[CX3](=[OX1])[#1,CX4,a!r0]",*C(=O)C(*)=O +31,Thiazolones,"[$([SX2]1[CX3]([CX4,a!r0])=[CX3]([CX4,a!r0])[CX3](=[OX1])[NX3]1([CX4,a!r0])),$([sX2]1[cX3]([CX4,a!r0])[cX3]([CX4,a!r0])[cX3](=[OX1])[nX3]1([CX4,a!r0]))]",* +32,"1, 2-Diamines","[CX4,a!r0][NX3H1][CX4][CX4][NX3H1][CX4,a!r0]",*[NH]CC[NH]* +33,Quaternary ammonium cation,"[NX4+]([CX4,a!r0])([CX4,a!r0])([CX4,a!r0])[CX4,a!r0]",*[N+](*)(*)* +34,Activated N-heterocycle halides,"[$(n1c([F,Cl])ncnc1),$(n1c([F,Cl])ccnc1),$(n1c([F,Cl])nccc1)]",* +35,Aromatic sulphuric acids and salts,"[a!r0][Sv4X3](=[OX1])[$([OH]),$([O-])]",*S(*)=O +36,Iso(thio)cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +37,Acid imides,"[NX3]1([#1,#6])[CX3](=[OX1])[CX3]([!R])=[CX3]([!R])[CX3]1(=[OX1])",*C1=C(*)C(=O)N(*)C1=O +38,Activated N-heterocycles,"[$(n1c([F,Cl,$([CX2]#[NX1])])nccc1),$(n1cnccc1([F,Cl,$([CX2]#[NX1])])),$(n1cncnc1([F,Cl,$([CX2]#[NX1])]))]",* +39,Dialkyl sulfonates,[CX4][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +40,Dialkyl sulfates,[CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(=O)(=O)OC +41,Ring strained amides,[NX3H1]1[CX4][CX4][CX3]1(=[OX1]),O=C1CC[NH]1 +42,Aldehydes and precursors,"[$([#1,#6;!$(C=C);!$(C#C)][CX3]([H])(=[OX1])),$([CX4;H1]([OX2])[OX2])]",* +43,"α, β-Unsaturated carbonyls","[CX3]=[CX3][CX3](=[OX1])[$([OX2]([CX3]=[OX1])[!#1]),$([#1][CX3]=[OX1]),$([NX3H2]([CX3]=[OX1])),$([NX3]([CX3]=[OX1])),$([CX4][CX3]=[OX1])]",*C(=O)C=C +44,Hydroquinones,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +45,Catechols,[OH1]c1c([OH1])cccc1,[OH]c1ccccc1[OH] +46,Resorcinols,[OH1]c1cc([OH1])ccc1,[OH]c1cccc([OH])c1 +47,O-Alkyl hydroquinones precursors,[OH1]c1ccc([OX2][CX4])cc1,COc1ccc([OH])cc1 +48,O-Alkyl resorcinols precursors,[OH1]c1cc([OX2][CX4])ccc1,COc1cccc([OH])c1 +49,O-Alkyl catechols precursors,[OH1]c1c([OX2][CX4])cccc1,COc1ccccc1[OH] +50,Thiols,[#16X2H1],[SH] +51,Disulfides,*[#16X2][#16X2]*,*SS* +52,Diaryl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[a!r0],*C(=O)OOC(*)=O +53,Arylacyl peroxides,[a!r0][CX3](=[OX1])[OX2][OX2][CX3](=[OX1])[A],*C(=O)OOC(*)=O +54,Haloamides,"[#6][CX3](=[OX1])[NX3]([F,Cl,Br,I])[#6]",*N(C)C(C)=O +55,Hydroperoxides and precursors,[#6][OX2][OX2][OH1],COO[OH] +56,"1,2-Dihydroxy aromatic compounds",[OH1]aa[OH1],[OH]*:*[OH] +57,"1,4-Dihydroxy aromatic compounds",[OH1]aaaa[OH1],[OH]*:*:*:*[OH] +58,2 or 4-Hydroxysubstituted alkylphenyl ether,"[$(c1c([OX2][CX4])c([OH1])ccc1),$(c1c([OX2][CX4])ccc([OH1])c1)]",* +59,Aromatic amines,"[a!r0][$([NX3H2]),$([NX3H1][#6])]",** +60,Aromatic amines precursors,"[$([a!r0][NH1][CX3](=[OX1])),$(c1c([NX2]=[NX2][a!r0])ccc([$([NX3]([CX4])([CX4])),$([NX3H1][CX4]),$([NH2]),$([OH1])])c1)]",* +61,Alkyl or aryl sylfonyl halides,"[CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +62,Sulfonamides,"c1c([Sv6X4](=[OX1])(=[OX1])[NX3H1][$([#1]),$([CX4]),$([a!r0])])ccc([NX3H2])c1",*[NH]S(=O)(=O)c1ccc([NH2])cc1 +63,Dithiocarbamates,[SX2][CX3](=[SX1])[NX3],NC(S)=S +64,Hydrazines,"[#6&!$([CX3]=[OX1,SX1,NX2])][NX3H1][NX3H2,$([NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])])]",*[NH]C +65,Aromatic nitro (general),"[a!r0][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",** +66,Aromatic amine (general),[a!r0][NX3H2],*[NH2] +67,Three-membered heterocycles (general),"[NX3H1,SX2,OX2]1[CX4][CX4]1",*1CC1 +68,Nitroso (general),[NX2]=[OX1],N=O +69,Unsubstituted heteroatom-bonded heteroatom (general),"[$([NX3H2]-[#7]),$([NX3H2]-[#8]),$([OX2H1]-[#7]),$([OX2H1]-[#8])]",* +70,Azo-type (general),[NX2]=[NX2],N=N +71,Aliphatic halide (general),"[CX4][Cl,Br,I]",*C +72,Polycyclic aromatic system (general),"[$([aR3]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))])]",* +73,Aromatic nitroso (specific),[a!r0][NX2]=[OX1],*N=O +74,Alkyl nitrite (specific),[OX1]=[NX2][OX2][CX4],CON=O +75,Nitrosamine (specific),"[OX1]=[NX2][NX3]([#6,#1])[#6,#1]",*N(*)N=O +76,Epoxide (specific),[CX4]1[OX2][CX4]1,C1CO1 +77,Aziridine (specific),[CX4]1[NX3H1][CX4]1,C1C[NH]1 +78,Azide (specific),"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +79,Diazo (specific),"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +80,Triazene (specific),[NX3!R][NX2!R]=[NX2!R],NN=N +81,Aromatic hydroxylamine (specific),[a!r0][NX3H1][OH1],*[NH][OH] +82,Aliphatic halide (specific),"[Cl,Br,I][$([CX4]);!$([CX3](=[OX1,SX1,NX2]));!$([CH2][CH2][SX2,NX3])]",** +83,Carboxylic acid halide (specific),"[Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +84,Nitrogen and sulphur mustard (specific),"[Cl,Br,I][CH2][CH2][SX2,NX3]",*[CH2][CH2]* +85,Bay-region in polycyclic aromatic hydrocarbons (specific),[cR1H1]1[cR1H1][cR1][cR1][cR2]2[cR2]1[cR2]3[cR2]([cR1][cR1]2)[cR1][cR1][cR1H1][cR1H1]3,c1cc2ccc3cc[cH][cH]c3c2[cH][cH]1 +86,K-region in polycyclic aromatic hydrocarbons (specific),[cR1]1[cR1][cR1][cR1H1][cR2]2[cR2]1[cR2]3c([cR1H1][cR1H1]2)[cR1H1][cR1][cR1][cR1]3,c1c[cH]c2[cH][cH]c3[cH]cccc3c2c1 +87,Sulfonate-bonded carbon atom (additional),[CX4][Sv6X4](=[OX1])(=[OX1])[OX2],CS(O)(=O)=O +88,"α, β-Unsaturated aldehyde (additional)",[CX3]=[CX3][CX3;H1]=[OX1],C=CC=O +89,Aliphatic N-nitro (additional),"[NX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1][O-]))]",*N +90,Diazonium (additional),"[$([a!r0][NX2+]#[NX1]),$([a!r0][NX2]#[NX1])]",* +91,β-Propiolactone (additional),[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +92,"α,β-Unsaturated alkoxy (additional)",[CX4][OX2][CX3H1]=[CX3H1],CO[CH]=[CH] +93,1-Aryl-2-monoalkyl hydrazine (additional),[a!r0][NX3H1]-[NX3H1][CX4],*[NH][NH]C +94,Aromatic methylamine (additional),[a!r0][NX3;H1][CH3],*N[CH3] +95,Aromatic hydroxylamine ester (additional),[a!r0][NH][OX2][CX3](=[OX1]),*[NH]OC=O +96,Polycyclic planar system (additional),[*R1]1[*R2]2=[*R1][*R1]=[*R1][*R1]=[*R2]2[*R1][*R2]3=[*R1][*R1]=[*R1][*R1]=[*R2]13,*1*2=**=**=*2**2=**=**=*12 +97,Acyl halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +98,N-Methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +99,Monohaloalkene,"[CX3]([CX4,#1])([F,Cl,Br,I])=[CX3]([CX4,#1])[!F!Cl!Br!I]",*C(*)=C(*)* +100,S or N mustard,"[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +101,Propiolactones or propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +102,Epoxides and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +103,Aliphatic halogens,"[CX4;!H0][Br,Cl,I]",*C +104,Alkyl nitrite,[OX1]=[NX2][OX2][CX4],CON=O +105,Simple aldehyde,"[CX3]([H])(=[OX1])[#1,#6&!$([CX3]=[CX3])]",*C([H])=O +106,Hydrazine,[NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])][NX3;!$([NX3](=[OX1])=[OX1]);!$([NX3+](=[OX1])[O-])],NN +107,Aliphatic azo and azoxy,"[$([C,#1][NX2]=[NX2][C,#1]),$([CX3]=[NX2+]=N),$([CX3]=[NX2+]=[NX1-]),$([CX3-][NX2+]#[NX1]),$([CX3][NX2]#[NX1]),$(C[NX2]=N(=O)[*]),$(C[NX2]=[N+]([O-])[*])]",* +108,Isocyanate and isothiocyanate groups,"[NX2]=[CX2]=[OX1,Sv2X1]",*=C=N +109,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +110,Thiocarbonyl,"[$([NX3][CX3](=[Sv2X1])[NX3]),$([CX3;!$(C[OH]);!$(C[SH]);!$(C[O-]);!$(C[S-]);!$(CO[#6])](=[Sv2X1])[NX3])]",* +111,Heterocyclic polycyclic aromatic hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +112,Alkyl and aryl N-nitroso groups,[#6][NX3][NX2]=[OX1],CNN=O +113,Azide and triazene groups,"[$([NX2!R]=[NX2!R][NX3!R]),$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N)]",* +114,Aliphatic N-nitro group,"[NX3]([#1,C])([#1,C])[$([NX3+](=[OX1])[O-]),$([NX3](=O)=O)]",*N(*)* +115,"α, β-Unsaturated aliphatic alkoxy group",C[CX3;H1]=[CX3;H1][OX2][#6],CC=COC +116,Aromatic nitroso group,[a!r0][NX2]=[OX1],*N=O +117,Aromatic ring N-oxide,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +118,Coumarins and furocoumarins,"[$(c1cccc2c1oc(=O)cc2),$(C1=CC(=O)OC2=CC=CC=C12),$(C1=CC(=O)Oc2ccccc12)]",* +119,Halogenated benzene,"c1ccccc1[$([Br,Cl,F,I]);!$([Br,Cl,F,I]aa[Br,Cl,F,I]);!$([Br,Cl,F,I]aaa[Br,Cl,F,I]);!$([Br,Cl,F,I]aa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aaa([OH])a([OH])a[OH]);!$([Br,Cl,F,I]aa([OH])a([OH])aa[OH])]",*c1ccccc1 +120,Halogenated PAH,"[Br,Cl,F,I][$([cR1]1[cR1][cR1][cR1][cR1][cR1]1-[cR1]2[cR1][cR1][cR1][cR1][cR1]2),$([cR1]1[cR1][cR1][cR1][cR2]2[cR2]1[cR1][cR1][cR1][cR1]2)]",** +121,Halogenated dibenzodioxins,"[OR1]1[CR2]2=[CR1][CR1]=[CR1][CR1]=[CR2]2[OR1][CR2]3=[CR1][CR1]([F,Cl,Br,I])=[CR1][CR1]=[CR2]13",*C1=CC=C2OC3=CC=CC=C3OC2=C1 +122,Primary and secondary aromatic amines,"[$([a!r0][NX3;H2]),$([a!r0][NX3;H1][CH3]),$([a!r0][NX3;H1][CH2][CH3])]",* +123,Tertiary aromatic amines,"a[NX3]([$([CH3]),$([CH2][CH3])])[$([CH3]),$([CH2][CH3])]",*N(*)* +124,Secondary aromatic acetamides and formamides,"[$([a!r0][NX3;H1][CX3;H1](=[OX1])),$([a!r0][NX3;H1][CX3](=[OX1])[CH3])]",* +125,Nitroarenes,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=O)(=O))]",** +126,Nitrosoarenes,[a!r0][NX2]=[OX1],*N=O +127,Arylhydroxylamines,"[a!r0][NX3;H1][OX2][#1,#6]",*NO* +128,N-Nitroso-N-dialkylamines,[NX3]([CX4])([CX4])[NX2]=[OX1],CN(C)N=O +129,N-Nitroso-N-alkylamides,"[CX4,a!r0][CX3](=[OX1])[NX3]([CX4])[NX2]=[OX1]",*C(=O)N(C)N=O +130,N-Nitroso-N-alkylureas,"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[NX3H1][CX4,a!r0]",*[NH]C(=O)N(C)N=O +131,N-Nitroso-N-alkylcarbamates (aka urethanes),"[OX1]=[NX2][NX3]([CX4])[CX3](=[OX1])[OX2][CX4,a!r0]",*OC(=O)N(C)N=O +132,N-Nitroso-N-alkylnitriles,[OX1]=[NX2][NX3]([CX4])[CX2]#[NX1],CN(C#N)N=O +133,N-Nitroso-N-hydroxylamines,[OX1]=[NX2][NX3]([OH1])[#6],CN([OH])N=O +134,Benzylic halides,"[a!r0][CH2][Cl,Br,I]",*[CH2]* +135,Oxiranes and aziridines,"[CX4]1[OX2,NX3][CX4]1",*1CC1 +136,Propiolactones,[OX2]1[CX4][CX4][CX3]1(=[OX1]),O=C1CCO1 +137,Alkyl esters of sulfonic and sulphuric acids,"[$([CX4,a!r0][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,a!r0][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][$([CH3]),$([CH2][CH3])])]",* +138,Alkyl esters of phosphonic and phosphoric acids,"[$([CX4,a!r0][Pv5X4](=[OX1])([OX2][$([CH3]),$([CH2][CH3])])[OX2][$([CH3]),$([CH2][CH3])]),$([CX4,#1][OX2][Pv5X4](=[OX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])])]",* +139,Mixed alkyl esters of thiophosphoric acid,"[CX4][OX2][Pv5X4](=[SX1])([OX2][CX4,#1])[OX2][$([CH3]),$([CH2][CH3])]",*OP(=S)(O*)OC +140,Haloethylamines,"[NX3]([#1,#6])([#1,#6])[CH2][CH2][Cl,Br,I,F]",*[CH2][CH2]N(*)* +141,Haloalkylethers,"[$([#6][OX2][CH2][CH2][Cl,Br,I]),$([#6][OX2][CH2][Cl,Br,I])]",* +142,α-Halocarbonyl or a-halohydroxy,"[$([CX3](=[OX1])[CH2][Cl,Br,I]),$([CX4!H0]([OH1])[CH2][Cl,Br,I])]",* +143,Haloamines,"[#6][NX3]([#6])[Cl,Br,I,F]",*N(C)C +144,Allylic halides and alkoxides,"[CX3]=[CX3][CH2][$([Cl,Br,I]),$([OX2])]",*[CH2]C=C +145,Halogenated methanes,"[CX4]([H,F,Cl,Br,I])([H,F,Cl,Br,I])([H,F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)* +146,Vinyl halides,"[CX3]=[CX3H1][Cl,Br,I]",*[CH]=C +147,Isocyanate,[NX2]=[CX2]=[OX1],N=C=O +148,Isothiocyanate,[NX2]=[CX2]=[SX1],N=C=S +149,Alkyl esters of phosphonic or sulphonic acids,"[$([CX4,a][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]),$([CX4,a][Pv5X4](=[OX1])([OX2][#1,CX4])[OX2][CX4])]",* +150,Aromatic nitro groups,"[a!r0][$([NX3+](=[OX1])[O-]),$([NX3](=[OX1])=[OX1]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +151,Aromatic rings N-oxides,[O-][N+]1=CC=CC=C1,[O-][N+]1=CC=CC=C1 +152,Aromatic mono- and dialkylamino groups,"[a!r0][$([NX3H1][CH3]),$([NX3H1][CH2][CH3]),$([NX3]([CH3])[CH3]),$([NX3]([CH3])[CH2][CH3]),$([NX3]([CH2][CH3])[CH2][CH3]);!$([NX3]a(a-[!#1])a-[!#1]);!$([NX3]aa-C(=[OX1])[OH])]",** +153,Alkyl hydrazines,"[NX3]([CX4])([#1,CX4])[NX3]([#1,CX4])[#1,CX4]",*N(*)N(*)C +154,Alkyl aldehydes,"[$([CX3]([H])(=[OX1])[#1,CX4])&!$([CX3]([H])(=[OX1])[CX3]=[CX3])]",* +155,Monohaloalkenes,"[CX3]([CX4,#1])(Cl)=[CX3]([!F!Cl!Br!I])[CX4,#1]",*C(*)=C(*)Cl +156,"β-Haloethyl N, S - mustards","[F,Cl,Br,I][CH2][CH2][NX3,SX2][CH2][CH2][F,Cl,Br,I]",*[CH2][CH2]*[CH2][CH2]* +157,N-Chloroamines,[#6][NX3]([#6])Cl,CN(C)Cl +158,Propiolactones and propiosultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +159,Aromatic and aliphatic aziridinyl derivatives,[CX4]1[NX3][CX4]1,C1CN1 +160,Aromatic and aliphatic substituted primary alkyl halides,"[F,Cl,Br,I][CH2][CX4,a]",*[CH2]* +161,Derivatives of urethane (carbamates),[NX3][CX3](=[OX1])[OX2],NC(O)=O +162,Aliphatic and aromatic epoxides,"[$([CX4]1[OX2][CX4]1),$([#6]1=[#6][#8]1)]",* +163,Activated halo- or nitropyridines,"[$(c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])cc1),$(c1([F,Cl,Br,I,$(N(=O)=O)])ncccc1([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)]))]",* +164,2-Halo- or 2-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncccn1",*c1ncccn1 +165,4-Halo- or 4-nitropyrimidines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncncc1",*c1ccncn1 +166,Activated 2-halo- or 2-nitropyrazines,"c1([F,Cl,Br,I,$(N(=O)=O)])ncc([F,Cl,Br,I,$(N(=O)=O),$(C#N),$(C=O),$(C(F)(F)F),$(S=O)])nc1",*c1cnc(*)cn1 +167,Halo- or nitro s-triazines,"c1nc([F,Cl,Br,I,$(N(=O)=O)])ncn1",*c1ncncn1 +168,Formaldehyde and thioformaldehyde,"[CH2]=[OX1,SX1]",*=C +169,Aliphatic aldehydes and thioaldehydes,"[CX4][CX3H1]=[OX1,SX1]",*=[CH]C +170,Aromatic aldehydes,[a][CX3H1]=[OX1],*[CH]=O +171,"α, β-Unsaturated carbonyl and thiocarbonyl compounds","C(C)(C)=CC=[OX1,SX1]",*=CC=C(C)C +172,"α, β-Unsaturated ketones and thioketones","[C;!r5]([C;!r5])=[C;!r5][C;!r5](C)=[OX1,SX1;!r5]",*=C(C)C=CC +173,α-Diketones and α-dithiones,"[#6]C(=[OX1,SX1])C(=[OX1,SX1])[#6]",*=C(C)C(=*)C +174,β-Diketones and β-dithiones,"[#6]C(=[OX1,SX1])[CX4]C(=[OX1,SX1])[#6]",*=C(C)CC(=*)C +175,"C-Nitroso compounds, iso(thio)cyanates, (thio)cyanate esters","[#6][$([NX2]=O),$(N=C=O),$(OC#N),$(SC#N),$(N=C=S)]",*C +176,Primary alkyl amines,[CH2][NH2],[CH2][NH2] +177,Tertiary alkyl amines,[CH2][NX3]([CH3])[CH3],[CH2]N([CH3])[CH3] +178,"α, β-Unsaturated alkoxy","[$(CC(C)=[CH][CH2][OH]),$(CC=C(C)[CH2][OH])]",* +179,Three-membered heterocycles derivatives,"[CH,CH2,CH3;!$([CH2]CC=[O,S])]([F,Cl,Br,I,$(OS(=O)(=O)[#6,#1]),$(OS(=O)(=O)O[#6,#1])])[#6]1[O,N,SX2][#6]1",**C1*C1 +180,Lactones and their thio analogues,"C1C(=[O,S])[O,S][CH2,CH]1",*=C1**C1 +181,Esters of aromatic and unsaturated alcohols and their thio analogues,"[$(C=C),$(C#C),a][CH2,CH][O,S][$([CH]=O),$([CH]=S),$(C(C)=O),$(C(C)=S)]",**** +182,Aryloxy (arylthio) containing unsaturated compounds,"[$(C=C),$(C#C),a][CH2,CH][O,S][a]",**** +183,Aliphatic N-(thio)nitroso compounds,"[CH2,CH3][NX3][NX2]=[O,S]",*NN=* +184,Anthracene and anthracene-containing compounds,c1ccc2cc3ccccc3cc2c1,c1ccc2cc3ccccc3cc2c1 +185,Phenanthrene and phenanthrene-containing compounds,c1ccc2c(c1)ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +186,Activated alkene (Michael acceptor) (1),"[CH2,CH]=[CH][$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*[CH]=* +187,Activated alkene (Michael acceptor) (2),"[CH2]=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C +188,Activated alkene (Michael acceptor),"aC=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C* +189,Activated alkine,"C#C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C#C +190,Activated conjugated dienes,"[CH2,CH]=[CH]C=C[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C=C[CH]=* +191,Alkenes containing a gem-dihalo-substituted terminal double bond,"C=C([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)=C +192,Ortho-disubstituted benzenes,"c1c([O,NH2,NH])c([O,NH2,NH])ccc1",*c1ccccc1* +193,Para-disubstituted benzenes,"c1c(=[O,NH2,NH])ccc(=[O,NH2,NH])c1",*=c1ccc(=*)cc1 +194,Haloanhydrides,"[F,Cl,Br,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +195,Acylimidazoles,[#6][CX3](=[OX1])n1cncc1,CC(=O)n1ccnc1 +196,Acylbenzotriazoles,[#6][CX3](=[OX1])n1nnc2ccccc12,CC(=O)n1nnc2ccccc21 +197,Anhydrides and mixed anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +198,Phosphorus halogen derivatives (1),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#6])[#6]",*P(C)(C)=O +199,Phosphorus halogen derivatives (2),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#6]",*P(C)(O)=O +200,Phosphorus halogen derivatives (3),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#8])[#8]",*P(O)(O)=O +201,Phosphorus halogen derivatives (4),"[Pv5X4](=[OX1])([F,Cl,Br,I])([#7])[#6]",*P(C)(N)=O +202,Phosphorus halogen derivatives (5),"[Pv5X4]([F,Cl,Br,I])([#6])([#6])=[SX1]",*P(C)(C)=S +203,Phosphorus halogen derivatives (6),"[Pv5X4]([#8])([#6])([F,Cl,Br,I])(=[SX1])",*P(C)(O)=S +204,Phosphorus halogen derivatives (7),"[Pv5X4](=[SX1])([F,Cl,Br,I])([#16])[#6]",*P(C)(S)=S +205,Phosphorus V derivatives,[Pv5X4]([!#1])([!#1])([!#1])=[NX2],*P(*)(*)=N +206,Carbodiimides,[#6][NX2]=[CX2]=[NX2][#6],CN=C=NC +207,Thiocyanates,[SX2][CX2]#[NX1],N#CS +208,Sulfonylhalides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +209,Sulfonylanhydrides,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][Sv6X4](=[OX1])(=[OX1])[#6],CS(=O)(=O)OS(C)(=O)=O +210,Alkylsulfonates,[#6][Sv6X4](=[OX1])(=[OX1])[OX2][CX4],COS(C)(=O)=O +211,Alkylsulfates,"[#6,#1][OX2,OH1][Sv6X4](=[OX1])(=[OX1])[OX2][CX4]",**S(=O)(=O)OC +212,All types of 3-valent phosphorus and similar (1),[Pv3X3]([#8])([#8])[#8],OP(O)O +213,All types of 3-valent phosphorus and similar (2),"[Pv3X3]([#8])([#8])[F,Cl,Br,I]",*P(O)O +214,All types of 3-valent phosphorus and similar (3),"[Pv3X3]([#8])([#6])[F,Cl,Br,I]",*P(C)O +215,All types of 3-valent phosphorus and similar (4),"[Pv3X3]([#6])([#6])[F,Cl,Br,I]",*P(C)C +216,All types of 3-valent phosphorus and similar (5),[Pv3X3]([#6])([#6])([#6]),CP(C)C +217,All types of 3-valent phosphorus and similar (6),"[Pv3X3]([#8])([#7])[F,Cl,Br,I]",*P(N)O +218,All types of 3-valent phosphorus and similar (7),"[Pv3X3]([#7])([#7])[F,Cl,Br,I]",*P(N)N +219,All types of 3-valent phosphorus and similar (8),"[#16][Pv3X3]([#6])[F,Cl,Br,I]",*P(C)S +220,All types of 3-valent phosphorus and similar (9),[Pv3X3]([#7])([#7])[#7],NP(N)N +221,All types of 3-valent phosphorus and similar (10),[PX4+]([#6])([#6])([#6])([#6]),C[P+](C)(C)C +222,Hydroxamic acid haloanhydrides,"[CX3]([#6])([F,Cl,Br])=[NX2][#8]",*C(C)=NO +223,Halothioanhydrides,"[#6][CX3](=[SX1])[F,Cl,Br,I]",*C(C)=S +224,Halocarbonates,"[#8][CX3](=[OX1])[F,Cl,Br,I]",*C(O)=O +225,Halocarbamates,"[#7][CX3](=[OX1])[F,Cl,Br,I]",*C(N)=O +226,Isocyanides,"[#6][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +227,Azides,"[$([NX2]=[NX2+]=[NX1-]),$(N=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",* +228,Thione esters,"[#6,#1][CX3](=[SX1])[OX2][#6]",*C(=S)OC +229,Acylsulfides,"[#6,#1][CX3](=[OX1])[SX2][#6]",*C(=O)SC +230,Thiones,[#6][CX3](=[SX1])[#6],CC(C)=S +231,Thioamides,[#6][CX3](=[SX1])[#7],CC(N)=S +232,Peroxides,[OX2][OX2],OO +233,Acyclic disulfides and polysulfides,[SX2!R][SX2!R],SS +234,Nitroso,[#6][NX2]=[OX1],CN=O +235,Nitrates,"[#6][OX2][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*OC +236,N-Nitro,"[#7][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*N +237,N-Nitroso,[#7][NX2]=[OX1],NN=O +238,Azo,[#6][NX2]=[NX2][#6],CN=NC +239,Azoxy,"[#6][$([NX2]=[NX3+]([O-])[#6]),$([NX2]=[NX3](=[OX1])[#6])]",*C +240,Nitroso dimers,"[$([#6][NX3+]([OX1-])=[NX3+]([OX1-])[#6]),$([#6][NX3](=[OX1])=[NX3](=[OX1])[#6])]",* +241,Sulfenyl halides,"[#6][Sv2X2][F,Cl,Br,I]",*SC +242,Sulfinyl halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +243,Diazonium salts,"[$([NX2+]#[NX1]),$([NX2]#N)]",* +244,Cyclic and linear haloamidines,"[CX3](=[#7])([#7])[Cl,Br,I]",*C(N)=N +245,Aldimines and ketimines,[#6][CX3]=[NX2][#6],CC=NC +246,Hydrazones and similar,[CX3]=[NX2][NX3][#6],CNN=C +247,Hydroxylamines,[OH1][NX3][#6],CN[OH] +248,N-Oxides,"[$([OX1-,OH1][#7X4+]([*])([*])([*])),$([OX1]=[#7X4v5]([*])([*])([*])),$([OX1]=[Nv5X3&!$([Nv5X3](=[OX1])=[OX1])](=[*])([*])),$([OX1-,OH1][#7X3+R](~[R])(~[R])),$([OX1]=[#7v5X3R](~[R])(~[R]))]",* +249,Aminals,N[CX4]N,NCN +250,Ammonium salts,[NX4+]([#6])([#6])([#6])([#6]),C[N+](C)(C)C +251,Sulfonium salts,[SX3+]([#6])([#6])([#6]),C[S+](C)C +252,α-Haloketones and similar,"[#6][CX3](=[OX1])[CX4][Cl,Br,I]",*CC(C)=O +253,β-Haloamines,"[NX3][CX4][CX4][Cl,Br,I]",*CCN +254,β-Halosulfides,"[Sv2X2][CX4][CX4][Cl,Br,I]",*CCS +255,Acrylates and similar,[CX3](=[OX1])([#8])[CX3]=[CX3],C=CC(O)=O +256,Acrylamides,[CX3](=[OX1])([#7])[CX3]=[CX3],C=CC(N)=O +257,Vinylketones and similar,[CX3](=[OX1])([#6])[CX3]=[CX3],CC(=O)C=C +258,Vinylsulfones and similar,[Sv6X4](=[OX1])(=[OX1])[CX3]=[CX3],C=CS(=O)=O +259,Nitrovinyl,"[CX3]=[CX3][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +260,Acrylonitriles,[NX1]#CC=C,C=CC#N +261,Vinylphosphonates and similar,[Pv5X4](=[OX1])([#8])([#8])[CX3]=[CX3],C=CP(O)(O)=O +262,Vinylpyridines and similar,"[$(n1c([CX3]=[CX3])cccc1),$(n1cc([CX3]=[CX3])ccc1),$(n1ccc([CX3]=[CX3])cc1)]",* +263,Cyclic maleimide-like Michael acceptors,C1(=[OX1])C=CC(=[OX1])[NX3]1,O=C1C=CC(=O)N1 +264,Ketenes,[CX3]=[CX2]=[OX1],C=C=O +265,Allenes,C=C=C,C=C=C +266,Oxiranes,[CX4]1[OX2][CX4]1,C1CO1 +267,Thiiranes,[CX4]1[SX2][CX4]1,C1CS1 +268,Aziridines,[CX4]1[NX3][CX4]1,C1CN1 +269,Oxetanes,[CX4]1[OX2][CX4][CX4]1,C1COC1 +270,Thietanes,[CX4]1[SX2][CX4][CX4]1,C1CSC1 +271,Selen in chain,[Sev2X2],[SeH2] +272,O-Silyl derivatives,[Si]([#8])([#6])([#6])([#6]),C[Si](C)(C)O +273,N-Silyl derivatives,[Si]([#7])([#6])([#6])([#6]),C[Si](C)(C)N +274,Benzylhalogenides and similar,"c1ccccc1([CX4][Cl,Br,I])",*Cc1ccccc1 +275,Halomethyl ethers,"[F,Cl,Br,I][CX4][#8]",*CO +276,Halomethyl thioethers,"[F,Cl,Br,I][CX4][#16]",*CS +277,Halomethyl amines,"[F,Cl,Br,I][CX4][#7]",*CN +278,Iodoso and similar hypervalent compounds,[OX1]=[I!X1][#6],CI=O +279,Linear thioureas,N[CX3](=[SX1])N,NC(N)=S +280,Linear dithiocarbamates,N[CX3](=[SX1])S,NC(S)=S +281,Trithiocarbonates,[CX3](=[SX1])(S)S,SC(S)=S +282,Thioester,[CX3](=[SX1])([#6])S,CC(S)=S +283,Bunte salts,[Sv6X4](=[OX1])([#8])([#8])[SX2][#6],CSS(O)(O)=O +284,Positively charged N-heterocycles,[#7v4X3R],N +285,Organometallic compounds,"[$([Te]~[#6]),$([As]~[#6]),$([Ge]~[#6]),$([Hg]~[#6]),$([Co]~[#6]),$([Fe]~[#6]),$([Mn]~[#6]),$([Cr]~[#6]),$([Ti]~[#6]),$([Sn]~[#6])]",* +286,"Isothiazolinone, isothiazolinthione and their derivatives","[#6]1=,:[#6]C(=[OX1,SX1])N[SX2]1",*=C1C=CSN1 +287,Acyl and thioacyl halides,"[!$(C=C);!$(C#C)]C(=[O,SX1])[F,Cl,Br,I]",*C(*)=* +288,Imidoyl halides,"[!$(C=C);!$(C#C)]C(=N)[F,Cl,Br,I]",*C(*)=N +289,Esters of aromatic alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][a]",**C(*)=* +290,Acid anhydrides and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N]C(=[O,SX1,N])",*C(=*)*C=* +291,Esters of unsaturated alcohols and their thio and aza analogues,"[!$(C=C);!$(C#C)]C(=[O,S,N])[O,S][$(C=C),$(C=N),$(C#C),$(C#N)]",**C(*)=* +292,"β-Lactones, β-lactams and their thio analogues","[#6]1C(=[O,S])[O,N,S][#6]1",*=C1*CC1 +293,Benzo-fused five-membered heterocycles,"[C,N,O,S,a]c1[n,o,s]c2ccccc2[n,o,s]1",*c1*c2ccccc2*1 +294,(Thio)carbonyl and imine derivatives of five-membered heterocycles,"[#6]1[#6](=[N,O,S])[#7,#8,#16][#6][#7,#8,#16]1",*=C1*C*C1 +295,Phthalic anhydrides and their thio and aza analogues,"[C,O]=[#6]1[#7,#8,#16][#6](=[O,N,SX1])c2ccccc12",*=C1*C(=*)c2ccccc21 +296,Acylating agents,"[!$(C=C);!$(C#C)]C(=[O,SX1,N])[O,S,N][CX4,O,S][$(C=O),a,$(C=C),$(C#C),$(C=N),$(C#N)]",***C(*)=* +297,Heteryl-substituted benzenes,"C1=[C,N][$(S(=O)(=O)),$(C=[N,O]),$(S=O)][C,N]=C1c2ccccc2",*1*=CC(c2ccccc2)=*1 +298,Cyclopentanone and cyclopentathione derivatives,"[CH2,CH]=C1C(=[OX1,SX1])**C1",*=C1**CC1=* +299,"Ortho-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])c([OH,NH2,NH,$(N=N),$(N(C)C)])ccc1",*c1ccccc1* +300,"Para-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])ccc([OH,NH2,NH,$(N=N),$(N(C)C)])c1",*c1ccc(*)cc1 +301,"Meta-substituted phenols, primary and secondary amines","c1c([OH,NH2,NH])cc([OH,NH2,NH,$(N(C)C)])cc1",*c1cccc(*)c1 +302,Ortho-hydroxysubstituted methyl phenyl ether,c1([OH])c(O[CH3])cccc1,[CH3]Oc1ccccc1[OH] +303,Para-hydroxysubstituted methyl phenyl ether,c1([OH])ccc(O[CH3])cc1,[CH3]Oc1ccc([OH])cc1 +304,Para-hydroxysubstituted iso-allyl benzene,c1c([OH])ccc(C=C[CH3])c1,[CH3]C=Cc1ccc([OH])cc1 +305,Haloethyl-substituted aromatic compounds,"C([F,Cl,Br,I])[CH2,CH][a]",**C* +306,Para-hydroxysubstituted allylbenzene,c1([OH])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc([OH])cc1 +307,Para-methoxysubstituted allylbenzene,c1(O[CH3])ccc([CH2][CH]=[CH2])cc1,C=[CH][CH2]c1ccc(O[CH3])cc1 +308,α-Naphthols,[OH]c1cccc2ccccc12,[OH]c1cccc2ccccc12 +309,vic-Difluoroalkyl group,"F[CH2,CH]C(F)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(F)*F +310,vic-Dichloroalkyl group,"Cl[CH2,CH]C(Cl)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Cl)*Cl +311,vic-Dibromoalkyl group,"Br[CH2,CH]C(Br)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(Br)*Br +312,vic-Diiodoalkyl group,"I[CH2,CH]C(I)[$(N(=[OX1])=[OX1]),$(C=O),$(C#N),$(S=O),$(C(=O)N),$(a)]",*C(I)*I +313,Carboxylic acid anhydrides,"[$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6]1),$([#6]1[CX3](=[OX1])[OX2][CX3](=[OX1])[#6][#6]1)]",* +314,Dialkyl carbamoylchloride,[NX3]([CX4])([CX4])[CX3](=[OX1])Cl,CN(C)C(=O)Cl +315,Lactones,"[$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6]1),$([#6&!$(C=[O,N,S])]1[OX2][CX3](=[OX1])[#6][#6]1)]",* +316,Sulfonic acid esters,[#6][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(C)(=O)=O +317,Sulfuric acid esters,[#6][OX2!R][Sv6X4!R](=[OX1])(=[OX1])[OX2!R][#6],COS(=O)(=O)OC +318,Phosphoric acid ester,[Pv5X4]([OX2][#6])([OX2][#6])([OX2][#6])(=[OX1]),COP(=O)(OC)OC +319,Cyclic sulfonic acid esters,"[$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +320,Cyclic sulfuric acid esters,"[$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6]1),$([#6]1[OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6][#6][#6]1)]",* +321,Halo acetates,"[F,Cl,Br,I][#6][CX3](=[OX1])[OX2H1]",*CC(=O)[OH] +322,Halo acetamides,"[F,Cl,Br,I][#6][CX3](=[OX1])[NX3]",*CC(N)=O +323,Halo ethers,"[$([F,Cl,Br,I]C[OX2]C),$([F,Cl,Br,I]CC[OX2]C)]",* +324,Haloethyl sulfides (S-mustard),"[F,Cl,Br,I][CX4][CX4][SX2]",*CCS +325,Haloethyl amines (N-mustard),"[F,Cl,Br,I][CH2][CH2][NX3]",*[CH2][CH2]N +326,"α, β-Unsaturated amides",[#6]=[#6][CX3](=[OX1])[NX3],C=CC(N)=O +327,"α, β-Unsaturated nitriles",C=CC#[NX1],C=CC#N +328,"α, β-Unsaturated aldehydes",C=C[CX3]([H])=[OX1],[H]C(=O)C=C +329,"α, β-Unsaturated nitro compounds","[#6]=[#6][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C=C +330,"α, β-Unsaturated sulfones",[#6]=[#6][Sv6X4](=[OX1])(=[OX1]),C=CS(=O)=O +331,"α, β-Unsaturated carboxylic acid ester (acrylates)",[#6]=[#6][CX3](=[OX1])[OX2][#6],COC(=O)C=C +332,"α, β-Unsaturated carboxylic acid",[CX3]=[CX3][CX3](=[OX1])[OX2H1],C=CC(=O)[OH] +333,"α, β-Unsaturated carbonyl compounds",[#6]=[#6][CX3](=[OX1])([!#1!$([OH1])]),*C(=O)C=C +334,Alkyl halide,"[*!$([a])&!$(C=C)&!$(C#C)][CX4][F,Cl,Br,I]",*C* +335,Aryl halide,"[a!r0][F,Cl,Br,I]",** +336,Halogenated allylic group,"[F,Cl,Br,I][CX4][CX3]=[CX3]",*CC=C +337,Halogenated benzylic group,"c[CX4][F,Cl,Br,I]",*Cc +338,Diazo compounds,"[$([#6]=[NX2+]=N),$([#6]=[NX2]=[NX1]),$([#6]=[NX2+]=[NX1-]),$([#6]-[NX2+]#[NX1]),$([#6-]-[NX2+]#[NX1])]",* +339,Organo metallic compounds,"[$([Cu][#6]),$([Ag][#6]),$([Au][#6]),$([Zn][#6]),$([Cd][#6]),$([Hg][#6]),$([Sn][#6]),$([Pb][#6]),$([As][#6]),$([Sb][#6])]",* +340,Ammonium compounds,[NX4+]([CX4])([CX4])([CX4])([CX4]),C[N+](C)(C)C +341,Sulfonium compounds,[SX3+]([CX4])([CX4])([CX4]),C[S+](C)C +342,Iodine,II,II +343,Hydrogen peroxide,[#1][OX2][OX2][#1],[H]OO[H] +344,Sulfoxides,[Sv4X3](=[OX1]),O=S +345,Sulfenyl iodides,[SX2][IX1],SI +346,Sulfoxides of aliphatic disulfides,[SX2][Sv4X3](=[OX1]),O=SS +347,Thiosulfonates,[SX2][Sv6X4](=[OX1])(=[OX1]),O=S(=O)S +348,Carboxy disulfides,[SX2][SX2][CX3](=[OX1])[OX2],OC(=O)SS +349,Arsenic (III) compounds,[OX1]=[AsX2],O=[AsH] +350,DDT (dichlorodiphenyltrichloroethane) and analogues,c1cc(ccc1[CH1](C(Cl)(Cl)Cl)c1ccc(cc1)Cl)Cl,Clc1ccc([CH](c2ccc(Cl)cc2)C(Cl)(Cl)Cl)cc1 +351,(Dithio) carbamates,"[OX2,SX2][CX3](=[OX1,SX1])[NX3]",*C(=*)N +352,Organotin compounds,[Sn][#6],C[Sn] +353,Pyrethroids,"[$(CC(=C[CH]1C([CH]1C(=O)OC1C(=C(C(=O)C1)CC=CC=C)C)(C)C)C),$(C(=C[CH]1C([CH]1C(=O)O[CH]1C(=C(C(=O)C1)CC=CC=C)C)(C)C)(C)C(=O)OC)]",* +354,Organophosphorothionate esters,"[Pv5X4](=[SX1])([OX2][#6])([OX2,SX2][#6])([OX2,SX2][#6])",C*P(=S)(*C)OC +355,Acetates,"[CH,$([C!R](=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R,NX3!R][$([a;r6]),$([a;r5]),$(C=C),$(C#C)]",***=* +356,Acyclic anhydrides,"[CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])](=[O,SX1])[O!R,SX2!R][CH,$([C!R]([O,SX2])(=[O,SX1])[#6!R])]=[O,SX1]",*=***=* +357,Dialkyl carbamoylhalides,"[NH2!R,$([NH!R](C=O)[#6!R]),$(N(C=O)([#6!R])[#6!R])]C(=O)[F,Cl,Br,I]",*C(*)=O +358,Phosphonic acid halides,"[#6]O[P!R](=O)(O[#6])[F,Cl,Br,I,$(C#N)]",*P(=O)(OC)OC +359,Cyclopropenones,"[#6]1([#1,#6])=,:[#6]([#1,#6])-,:[#6]1=O",*C1=C(*)C1=O +360,β-Lactones,C1C(=O)OC1,O=C1CCO1 +361,Thio-lactones,C1C(=O)SC1,O=C1CCS1 +362,Azlactones,"C1=[O,SX2,NX2,CX3]CC(=[O,SX2])[O,SX2,NX3]1",*=C1*C=*C1 +363,Cyclic anhydrides,"[#6R,#8R,#16X2R][#6R](=[O,SX1])[#8R,#16X2R][#6R]([#6,#8R,#16X2])=[#8,#16X1]",*C(=*)*C(*)=* +364,Dithiocarbonimidic acid esters,[#6]N=C(S[#6])S[#6],CN=C(SC)SC +365,Polarised alkene-aldehydes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][CH]=O",*=*[CH]=O +366,Polarised alkene-ketones,"[$([$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[#6]);!$([#6X3]1=,:[#6X3H][CX3](=[OX1])[#6X3]=,:[#6X3][#6X3]1(=[OX1]));!$([CX3]1(=[OX1])[CX3](=[OX1])[#6X3]=,:[#6X3H][#6X3]=,:[#6X3]1)]",* +367,Polarised alkene-esters,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)O[#6]",*=*C(=O)OC +368,Polarised alkene-amides,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)*=* +369,Polarised alkene-nitros,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",**=* +370,Polarised alkene-cyanos,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C#N",*=*C#N +371,Polarised alkene-alkyl sulphonates,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)O[#6]",*=*S(=O)(=O)OC +372,Polarised alkene-alkyl sulfones,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]S(=O)(=O)[#6]",*=*S(C)(=O)=O +373,Polarised alkene-alkyl sulfinyls,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][SX3](=O)[#6]",*=*S(C)=O +374,Polarised alkene-oximes,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]C=[NX2][OH]",*=*C=N[OH] +375,Polarised alkene-pyridines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncccc1),$(c1ccncc1)]",**=* +376,Polarised alkene-pyrazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])]c1nccnc1",*=*c1cnccn1 +377,Polarised alkene-pyrimidines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncc1),$(c1ncccn1),$(c1cncnc1)]",**=* +378,Polarised akene-triazines,"[$([CH2]),$([CH][#6])]=[CH,$(C[#6])][$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1),$(c1nnncc1),$(c1cnnnc1)]",**=* +379,Azocarbonamides,"[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]C(=O)N=NC(=O)[NH2,$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)N=NC(*)=O +380,Allyl alcohols,"[CH2,$([CH](=C)[#6])]=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",*=*[CH2][OH] +381,Sulphone-sulfates,[#6][Sv6X4](=[OX1])(=[OX1])[CX4][CX4][OX2][Sv6X4](=[OX1])(=[OX1])[OH1],CS(=O)(=O)CCOS(=O)(=O)[OH] +382,Polarised alkyne-aldehydes,"[CH,$(C(#C)[#6])]#C[CH]=O",*#C[CH]=O +383,Polarise alkyne-ketones,"[CH,$(C(#C)[#6])]#CC(=O)[#6]",*#CC(C)=O +384,Polarised alkyne-esters,"[CH,$(C(#C)[#6])]#CC(=O)O[#6]",*#CC(=O)OC +385,Polarised alkyne-amides,"[CH,$(C(#C)[#6])]#CC(=O)[$([NH2]),$([NH](C=O)[#6]),$(N(C=O)([#6])[#6])]",*C(=O)C#* +386,Polarised alkyne-nitros,"[CH,$(C(#C)[#6])]#C[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",*C#* +387,Polarised alkyne-cyano,"[CH,$(C(#C)[#6])]#CC#N",*#CC#N +388,Polarised alkyne-alkyl sulphonates,"[CH,$(C(#C)[#6])]#CS(=O)(=O)O[#6]",*#CS(=O)(=O)OC +389,Polarised alkyne-alkyl sulfones,"[CH,$(C(#C)[#6])]#CS(=O)(=O)[#6]",*#CS(C)(=O)=O +390,Polarised alkyne-alkyl sulfinyls,"[CH,$(C(#C)[#6])]#C[SX3](=O)[#6]",*#CS(C)=O +391,Polarised alkyne-pyridines,"[CH,$(C(#C)[#6])]#C[$(c1ncccc1),$(c1ccncc1)]",*C#* +392,Polarised alkyne-pyrazines,"[CH,$(C(#C)[#6])]#Cc1nccnc1",*#Cc1cnccn1 +393,Polarised alkyne-pyrimidines,"[CH,$(C(#C)[#6])]#C[$(c1ncccn1),$(c1cncnc1),$(c1ncncc1)]",*C#* +394,Polarised alkyne-triazines,"[CH,$(C(#C)[#6])]#C[$(c1ncncn1),$(c1nncnc1),$(c1nnccn1),$(c1cnncn1)]",*C#* +395,Propargyl alcohols,"[CH,$(C(#C)[#6])]#C[CH2][OH]",*#C[CH2][OH] +396,Benzoquinones,"[$(C1(=O)[#6]=,:[#6]C(=O)[CH]=C1),$(C1(=O)C(=O)[#6]=,:[#6][CH]=C1)]",* +397,Quinone-imines,"[$(C1(=O)[#6]=,:[#6][$(C=[NH]),$(C=N[CX4])][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][CH]=C1),$(C1(=O)[$(C=[NH]),$(C=N[CX4])]C=[CH][#6]=,:[#6]1)]",* +398,Quinone-diimines,"[$([CH]1=C[$(C=[NH]),$(C=N[CX4])][#6]=,:[#6][$(C=[NH]),$(C=N[CX4])]1),$([CH]1=C[$(C=[NH]),$(C=N[CX4])][$(C=[NH]),$(C=N[CX4])][#6]=,:[#6]1)]",* +399,Aminophenols,"[$(c1([OH])c[cH]c([NH2])cc1),$(c1([OH])c([NH2])cc[cH]c1)]",* +400,Benzenediamines,"[$(c1([NH2])c[cH]c([NH2])cc1),$(c1([NH2])c([NH2])cc[cH]c1)]",* +401,Quinone-methides,"[$(C1=CC(=O)[#6]=,:[#6]C1(=[CH][CX4])),$(C1(=[CH][CX4])C(=O)[#6]=,:[#6]C=C1)]",* +402,Pyranones,"[$([cH]1cc(=[O,NH])cc[o,n]1),$([cH]1cc(=[O,NH])[o,n]cc1),$(c1cc(=[O,NH])[o,n][cH]c1)]",* +403,Poly aromatic hydrocarbons,"[c;R1,R2,R3]1[c;R1,R2,R3][c;R1,R2,R3][c;R2,R3]2[c;R2,R3]([c;R1,R2,R3]1)[c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3][c;R1,R2,R3]2",c1ccc2ccccc2c1 +404,Mono-aldehydes,"[CH2,$([CH](=O)[CX4]),$([CH](=O)c1a(*)caaa1),$([CH](=O)c1a(*)aaa1)]=O",*=O +405,Aliphatic amines,[#6][CH2][NX3H2],C[CH2][NH2] +406,"Di-substituted α,β-unsaturated alkenes (polarized by an aldehyde moiety)","[$(C(=C)([#6])[#6]);!$(C(=C)([#6])C=[CH2,CH])]=C[CH]=O",*=C[CH]=O +407,Di-substituted allyl alcohols,"C([#6])([#6])=[CH,$(C(=C)([CH2][OH])[#6])][CH2][OH]",CC(C)=*[CH2][OH] +408,"1,2-Dicarbonyls","[CH,$(C(=O)(C=O)[CX4]),$(C(=O)(C=O)c1a(*)aaaa1),$(C(=O)(C=O)c1a(*)aaa1)](=O)[CH,$(C(=O)(C=O)[#6]);!$(C(=O)(C=O)C=[CH2,CH]);!$(C(=O)(C=O)C#C)]=O",O=**=O +409,"1,3-Dicarbonyls","[CH,$(C(=O)([CX4]C=O)[CX4]),$(C(=O)([CX4]C=O)c1a(*)aaaa1),$(C(=O)([CX4]C=O)c1a(*)aaa1)](=O)[CX4][CH,$(C(=O)([CX4]C=O)[#6]);!$(C(=O)([CX4]C=O)C=[CH2,CH]);!$(C(=O)([CX4]C=O)C#C)]=O",O=*C*=O +410,Ethylenediamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][NH2]),$([NH]1[CH2][CH2][NH][CH2][CH2]1)]",* +411,Ethanolamines,"[$([NH2,$([NH]([CH2])[CX4])][CH2][CH2][OH]),$([NH]1[CH2][CH2]O[CH2][CH2]1)]",* +412,Piperizines,[NH]1CC[NH1]CC1,C1C[NH]CC[NH]1 +413,Morpholines,O1CC[NH1]CC1,C1COCC[NH]1 +414,Alkyl halides,"[CH3,$([CH2]([F,Cl,Br,I])[#6]),$([CH]([F,Br,Cl,I])([#6])[#6]);!$([CH2,CH]C=O);!$([CH2,CH][CX4][NX3,SX2]);!$([CH2,CH][CX4][F,Cl,Br,I])][F,Cl,Br,I]",** +415,Alkyl diazos,"[CH3,$([CH2](N=N)[#6]),$([CH](N=N)([#6])[#6])][NX2]=[NH,$(N(=N)[#6])]",*N=* +416,Alkyl sulfates,"[#6]OS(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(=O)(=O)OC +417,Alkyl sulphonates,"[#6]S(=O)(=O)O[CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",*OS(C)(=O)=O +418,Alkyl (thio)phosphates,"[#6][O,SX2]P(=[O,SX1])([O,SX2][#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(*C)*C +419,Alkyl (thio)phosphonates,"[#6][O,SX2]P(=[O,SX1])([#6])[O,SX2][CH3,$([CH2](O)[#6]),$([CH](O)([#6])[#6])]",**P(=*)(C)*C +420,Allyl acetates,"[#6]C(=[O,SX1])[O,SX2][CH2,$([CH]([O,SX2])[#6])][c,CX3,CX2]",***C(=*)C +421,α-Halocarbonyls,"[$([CH]=[O,SX1]),$(C([#6])=[O,SX1])][CH2,$([CH](C=[O,SX1])[#6])][F,Cl,Br,I]",*** +422,α-Haloalkynes,"[CH,$(C(#C)[#6])]#C[$([CH2](C#C)[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH](C#C)([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*C#* +423,α-Halobenzyls,"[c][$([CH2]([c])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])]),$([CH]([a])([#6])[F,Cl,Br,I,$(C#N),$(OS(=O)(=O)O[#6]),$(OS(=O)(=O)[#6])])]",*c +424,Sulfuranes,C1[SX2]C1,C1CS1 +425,Vinyl benzenes,c1([CX3!R]=[CX3!R])ccccc1,C=Cc1ccccc1 +426,Nitrosoureas,"[NX3]C(=O)[$([NH](C=O)[NX2]=O),$(N(C=O)([#6])[NX2]=O)]",*C(N)=O +427,Nitrosoguanidines,"[NX3]C(=[NH])[$([NH](C=[NH])[NX2]=O),$(N(C=[NH])([#6])[NX2]=O)]",*C(N)=N +428,N-Acytoxy-N-acetylphenyls,"[a][NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)* +429,N-Acytoxy-N-alkoxyamides,"[#6]O[NX3](O[$([CH](O)=O),$(C(=O)(O)[#6])])[$([CH](N)=O),$(C(=O)(N)[#6])]",*ON(*)OC +430,Thiosulphonates,[#6][SX2][SX4](=O)(=O)[#6],CSS(C)(=O)=O +431,Sulfoxides of disulfides,[#6][SX2][SX3](=O)[#6],CSS(C)=O +432,Aromatic sulphonic acids,[a][SX4](=O)(=O)[OH],*S(=O)(=O)[OH] +433,Isothiazol-3-ones,"[cH,$(c(c)([sX2])[#6])]1[cH,$(c(c)(c=O)[#6])]c(=O)[nH,$(n(c=O)([sX2])[#6])][sX2]1",O=c1*:*s*1 +434,Isothiazolin-3-ones,"[CH2,$([CH](C)([SX2])[#6])]1[CH2,$([CH](C)(C=O)[#6])]C(=O)[NH,$(N(C=O)([SX2])[#6])][SX2]1",O=C1**S*1 +435,N-Chloro-sulphonamides,[#6][SX4](=O)(=O)[NH]Cl,CS(=O)(=O)[NH]Cl +436,Polarized alkenes with a halogen leaving group,"C=[CH][F,Cl,Br,I]",*[CH]=C +437,Polarized alkenes with an alkyl sulphonate leaving group,C=[CH]OS(=O)(=O)[#6],CS(=O)(=O)O[CH]=C +438,Polarized alkenes with an alkyl sulfate leaving group,C=[CH]OS(=O)(=O)O[#6],COS(=O)(=O)O[CH]=C +439,Polarized alkenes with an alkyl (thio)phosphonate leaving group,"C=[CH]OP(=[O,SX])(O[#6])[#6]",*=P(C)(OC)O[CH]=C +440,Polarized alkenes with an alkyl (thio)phosphate leaving group,"C=[CH]OP(=[O,SX])(O[#6])O[#6]",*=P(OC)(OC)O[CH]=C +441,Mustards,"[NX3,SX2][CH2,$([CH]([NX3,SX2])([CX4])[CX4])][CH2,$([CH]([CX4])([Cl,Br,I])[CX4])][Cl,Br,I]",**** +442,"1,2-Dihaloalkanes","[Cl,Br,I][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][CH2,$([CH]([Cl,Br,I])([CX4])[CX4])][Cl,Br,I]",**** +443,Activated pentafluorobenzenes,"c1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-]),$([CH]=O),$(C#N),$(C(=O)[CH3])])c(F)c(F)c(F)c(F)c1(F)",*c1c(F)c(F)c(F)c(F)c1F +444,Formaldehyde releasers (1),"[$(O1COCC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C1),$([OX2H1]CC(Br)([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])C[OX2H1])]",* +445,Formaldehyde releasers (2),[#7X3]1(C[OH1])C(=[OX1])[#7X3](C[OH1])C([CH3])([CH3])C1(=[OX1]),[CH3]C1([CH3])C(=O)N(C[OH])C(=O)N1C[OH] +446,Formaldehyde releasers (3),"C1(=[OX1])[NX3H1]C(=[OX1])[NX3H1][CX4]1(C[OH1])[NX3H1][CX3](=[OX1])[NX3!H0][#1,#6]",*NC(=O)[NH]C1(C[OH])[NH]C(=O)[NH]C1=O +447,Formaldehyde releasers (4),[OH1][CX4][NX3H1][CX4][CX3](=[OX1])[OX2H1],O=C([OH])C[NH]C[OH] +448,Formaldehyde releasers (5),c1ccccc1[CX4][OX2][CX4][OH1],[OH]COCc1ccccc1 +449,"Hydrazine, hydrazides","[#6,#1][NX3H1][NX3H1][#6,#1]",*[NH][NH]* +450,Nitrobenzenes,"a[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]",** +451,Dibenzazepines,N([CX4])([CX4])C1=Nc2ccccc2[NX3H1]c3c1cccc3,CN(C)C1=Nc2ccccc2[NH]c2ccccc21 +452,Benzylamines,"[#1,CX4!R][NX3]([#1,CX4!R])[CH2]c1ccccc1",*N(*)[CH2]c1ccccc1 +453,Propargyl amines,"[#1,CX4,$(c1ccccc1)][CX2]#[CX2][NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*C#CN(*)* +454,Cyclopropyl amines,"[CX4]1[CX4][CX4]1[NX3]([#1,CX4,$(c1ccccc1)])[#1,CX4,$(c1ccccc1)]",*N(*)C1CC1 +455,"N-Substituted-4-aryl-1,2,3,6-tetrahydropyridines","[NX3]1([CX4!R])[CX4][CX3]=[CX3](c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2=CCN(C)CC2)c(*)c1* +456,N-Substituted-4-arylpiperidin-4-ol,"[NX3]1([CX4!R])[CX4][CX4][CX4]([OH1])(c2c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c([#1,#6,F,Cl,Br,I])c2([#1,#6,F,Cl,Br,I]))[CX4][CX4]1",*c1c(*)c(*)c(C2([OH])CCN(C)CC2)c(*)c1* +457,Formamides,[CX3H1](=[OX1])[NX3H1][#6],C[NH][CH]=O +458,Hydantoins (glycolylurea),"[NX3H1]1[CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NX3H1][CX3]1(=[OX1])",*C1(*)[NH]C(=O)[NH]C1=O +459,Thioureas,"[#1,#6][NX3]([#1,#6])[CX3](=[SX1])[#7]",*N(*)C(N)=S +460,Sulfonylureas,[#6][Sv6X4](=[OX1])(=[OX1])[NX3H1][CX3](=[OX1])[NX3H1][#6],C[NH]C(=O)[NH]S(C)(=O)=O +461,Ortho- or parahydroquinones,"[$(c1([OH1])c([OH1])cccc1),$(c1([OH1])ccc([OH1])cc1)]",* +462,Ortho- or paraquinones,"[$([#6]1(=[OX1])-,:[#6]=,:[#6]-,:[#6](=[OX1])-,:[#6]=,:[#6]1),$([#6]1(=[OX1])-,:[#6](=[OX1])-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)]",* +463,Ortho- or paraalkylphenols,"[$(c1([OH1])c([CX4]([#1,#6])[#1,#6])cccc1),$(c1([OH1])ccc([CX4]([#1,#6])[#1,#6])cc1)]",* +464,Quinone methide,"[$([OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]-,:[#6X3]1=[CX3]([#1,#6])[#1,#6]),$([OX1]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[CX3]([#1,#6])[#1,#6])-,:[#6]=,:[#6]1)]",* +465,Benzo-dioxolanes,c1ccc([OX2]2)c([OX2][CX4H1]2[OH1])c1,[OH][CH]1Oc2ccccc2O1 +466,3-Methylene indoles,"c1ccc([nX3]2([#1,#6]))c(c([CH2][#1,#6])c2)c1",*[CH2]c1cn(*)c2ccccc12 +467,Furans,c1ccc[oX2]1,c1ccoc1 +468,Thiophenes,c1ccc[sX2]1,c1ccsc1 +469,Thiazoles and 2-amino derivatives,"[$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([#1,CX4!R])[sX2]1),$(c1([#1,CX4!R])c([#1,CX4!R])[nX2]c([NX3]([#1,CX4!R])[#1,CX4!R])[sX2]1)]",* +470,Thiazolidinediones,[SX2]1[CX3](=[OX1])[NX3H1][CX3](=[OX1])[CX4]1[#6],CC1SC(=O)[NH]C1=O +471,2- or 4-Halopyridines,"[$(n1c([Cl,Br,I,F])cccc1),$(n1cccc([Cl,Br,I,F])cc1)]",* +472,Alkynes,"[#6][CX2]#[CX2][#1,#6]",*C#CC +473,Alkylhalides,"[$([CX4]([F,Cl,Br,I])([H,!F!Cl!Br!I])([H,!F!Cl!Br!I])[H,!F!Cl!Br!I]),$([CX4]([#6])([F,Cl,Br,I])([F,Cl,Br,I])[H,!F!Cl!Br!I])]",* +474,Carboxylic acids,[#6][CX3](=[OX1])[OH1],CC(=O)[OH] +475,Fluoroethyl ethers and amines,"[$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][OX2][#1,#6]),$([F][CX4][$([CH2]),$([CH]),$(C[OH1])][NX3][#6])]",* +476,Three-membered heterocycles,"[#6]1~[#6][#7,#8,#16]1",*1C~C1 +477,Thioles,[Sv2X2H1],[SH] +478,Chlor(brom)anhydrides,"[CX3](=[OX1])[Cl,Br]",*C=O +479,Sulphonic acids/esters,S(=O)(=O)O,OS(=O)=O +480,Trihalogensubstituted ketones,"[CX3](=[OX1])[CX4]([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C=O +481,Monohalogen substituted ketones,"[CX3](=[OX1])C[Cl,Br,I]",*CC=O +482,Sulphonhalogenanhydrides,"S(=[OX1])(=[OX1])[F,Cl,Br,I]",*S(=O)=O +483,Sulphonic acid,[Sv6X4](=[OX1])(=[OX1])[OH1],O=S(=O)[OH] +484,Phosphorus,P,P +485,Selen,[Se],[SeH2] +486,Bor,B,B +487,Silicium,[Si],[SiH4] +488,"Isocyanates, isothiocyanates","[NX2]=[CX2]=[OX1,SX1]",*=C=N +489,Thione,[CX3]=[SX1!R],C=S +490,β-halogen substituted carbonyls,"[CX3](=[OX1])CC[F,Cl,Br,I]",*CCC=O +491,β-hydroxy substituted carbonyls,[CX3](=[OX1])[C!H0]C[OH1],O=CCC[OH] +492,gem-Dihalo propane and cyclopropane,"CC([Cl,Br,I])([Cl,Br,I])C",*C(*)(C)C +493,Activated halides (o-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cc[F,Cl,Br]",*cc* +494,Activated halides (p-nitro substituted haloaromatics),"[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]cccc[F,Cl,Br]",*cccc* +495,Activated halides (α-halogen substituted N-heterocycles),"nc[F,Cl,Br]",*cn +496,Activated halides (γ-halogen substituted N-heterocycles),"nccc[F,Cl,Br]",*cccn +497,Thiourea,[#7][CX3](=[SX1])[#7],NC(N)=S +498,Barbiturates,"N1C(=[OX1,SX1])NC(=[OX1,SX1])C(=C)C1(=[OX1,SX1])",*=C1NC(=*)C(=C)C(=*)N1 +499,Alkyl chains,[CX4H2!R][CH2][CH2][CX4H2!R][CH2],[CH2][CH2][CH2][CH2][CH2] +500,"Non-cyclic 1,2-dicarbonyls compounds",C[C!R](=[OX1])[C!R](=[OX1])C,CC(=O)C(C)=O +501,Crown ethers,[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C[!#1!#6]C~C,*C~C*C~C*C~C*C~C*C~C*C~C +502,Coumarins (1),"c1cccc2c1oc(=O)c([$(C=[OX1]),$(C=[SX1]),$(S=[OX1]),$(C#[NX1]),F,Cl,Br,I,$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]));!$([CX3](=[OX1])[OH1])])[c!H0]2",*c1cc2ccccc2oc1=O +503,Coumarins (2),"[cH1]1[cH1]c2c3[cH1][cH1]c(cc3oc(=O)c2[cH1]c1[OX2][$([CH2]),$([CH3])])[OX2][C!H0]",*Oc1[cH][cH]c2c([cH]1)c(=O)oc1cc(OC)[cH][cH]c12 +504,Coumarins (3),c1cccc2c1oc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2o1 +505,Coumarins (4),c1cccc2c1nc(=[OX1])[c!H0]c2,O=c1ccc2ccccc2n1 +506,Coumarins (5),c1cccc2c1nc(=[NX2])[c!H0]c2,N=c1ccc2ccccc2n1 +507,Coumarins (6),"c1([F,Cl,Br,I])cc([F,Cl,Br,I])cc2c1oc(=[NX2H1])c([CX3](=[OX1])[NH2])[c!H0]2",*c1cc(*)c2oc(=N)c(C([NH2])=O)cc2c1 +508,Coumarins (7),c1cccc2c1oc(=[NX2])cc2,N=c1ccc2ccccc2o1 +509,Maleimides,C1(=[OX1])NC(=[OX1])[CX3H1]=[CX3]1,O=C1C=[CH]C(=O)N1 +510,"Michael acceptors (α,β-unsaturated carbonyls)",[CX3!H0!R]=[CX3!R][CX3]=[OX1],C=CC=O +511,Michael acceptors (acrylonitriles),[CX3!H0!R]=[CX3!R][CX2]#[NX1],C=CC#N +512,"Michael acceptors (α,β-unsaturated ketones)",C[CX3H1]=[CX3H1!R][CX3](=[OX1])C,C[CH]=[CH]C(C)=O +513,Michael acceptors (methyl acrylonitrile derivatives),C[CX3H1]=[CX3!R][CX2]#[NX1],C[CH]=CC#N +514,o-Quinones (3),"CC(=[OX1])C(=[OX1])[#6,#7]",*C(=O)C(C)=O +515,o-Quinones (5),CC(=[OX1])C(=S)C,CC(=O)C(C)=S +516,p-Quinones (2),"[#6]1=,:[#6]-,:[#6]=,:[#6]2-,:[#6](=,:[#6]1)-,:[#6](=[OX1])-,:[#6]4-,:[#6]3=,:[#6]2-,:[#8]-,:[#7]=,:[#6]3-,:[#6]=,:[#6]-,:[#6]4",O=C1C2CC=CC3=NOC(=C23)C2=CC=CC=C12 +517,p-Quinones (3),"[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[#6]2-,:[#6]1-,:[#6](=[OX1])-,:[#6]4=,:[#6]3-,:[#6]2=,:[#6](-,:[#6](=[OX1])-,:[#7]-,:[#6]3=,:[#6]-,:[#6]=,:[#6]4)O",OC1=C2C3=CC=CCC3C(=O)C3=C2C(=CC=C3)NC1=O +518,Hydroquinone,c1c([OH1])c([OH1])ccc1,[OH]c1ccccc1[OH] +519,N-N Single bound not in a ring,[N!R][N!R],NN +520,Ketal,CC([OX2]C)([OX2]C)C,COC(C)(C)OC +521,Acetal,[CX4H1](C)([OX2]C)([OX2]),CO[CH](C)O +522,Acyl and sulfinyl cyanide,"[$(C(=[OX1])[CX2]#[NX1]),$(S(=[OX1])[CX2]#[NX1])]",* +523,Amidotetrazole,"[#7]1([CX3]=[OX1])-,:[#6]=,:[#7]-,:[#7]=,:[#7]1",O=CN1C=NN=N1 +524,Hydrazine and other nucleophilic NH2-groups,"[NX3H2][#7,#8]",*[NH2] +525,Activated halo- and sulfonyl-aromatics,"c1([F,Cl,Br,I,$(C(C)=NO),$([CX2]#[NX1]),$([CX3]=[OX1]),$([CX4](F)(F)F),$([SX4](=[OX1])=[OX1]);!$([CX3](=[OX1])[OH1])])na([F,Cl,Br,I,$([SX4](=[OX1])(=[OX1])C)])a([!#7])a([!#7])a1",**1:*c(*)n*(*):*:1* +526,Rhodanines,N1C(=[SX1])[SX2]C(=C)[CX3]1=[OX1],C=C1SC(=S)NC1=O +527,Acyclic gem-dihalosubstituted carbon atom,"[C!R]([Cl,Br,I])[Cl,Br,I]",*C* +528,Imines,"[N!R]=[C,N]",*=N +529,Michael acceptors (carbonyl containing acrylonitrile derivatives),C[CX3H1]=[CX3!R](C(=[OX1])[!#1]~[!#1])[CX2]#[NX1],*~*C(=O)C(C#N)=[CH]C +530,Over halogenated rings,"a1c([F,Cl,Br,I])c([F,Cl,Br,I])ac([F,Cl,Br,I])a1",*c1*:*c(*)c(*)*1 +531,o-Quinones (1),"[CX3]1(=[!#1!#6])[CX3](=[!#1!#6])[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]1",*=C1C=CC=CC1=* +532,o-Quinones (2),CC(=[!#1!#6;!R])C(=[!#1!#6;!R])C,*=C(C)C(=*)C +533,o-Quinones (4),CC(=[!#1!#6;!R])S(=[OX1])(=[OX1]),*=C(C)S(=O)=O +534,p-Quinones (1),"[#6X3]1=,:[#6X3][CX3](=[!#1!#6])[#6X3]=,:[#6X3][#6X3]1(=[!#1!#6])",*=C1C=CC(=*)C=C1 +535,Other undesirable policyclic (adamantane derivatives),C1C4CC9CC1CC(C4)C9,C1C2CC3CC1CC(C2)C3 +536,"Other undesirable policyclic (1,3,5-triazaadamantane derivatives)",C1N4CN8CC1CN(C4)C8,C1C2CN3CN1CN(C2)C3 +537,"Other undesirable policyclic (2,3-dihydro-1H-phenalene derivatives)",c1ccc2c3c1cccc3CCC2,C1Cc2cccc3cccc(c23)C1 +538,Other undesirable policyclic (acenaphthene derivatives),c1ccc2c3c1cccc3CC2,C1Cc2cccc3cccc1c23 +539,Acid anhydrides and analogues,[!#1](=O)O[!#1]=O,O=*O*=O +540,Acyl halides and analogues,"[C,S](=[O,S])[F,Br,Cl,I]",**=* +541,Cyano carbonyl compounds ,N#CC(=O),N#CC=O +542,Methylendiamines (1),"[!$([C,S]=O)]N([!$([C,S]=O)])[CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*N(*)CN(*)* +543,Methylendiamines (2),"[!$([C,S]=O)][NH][CX4]N([!$([C,S]=O)])[!$([C,S]=O)]",*[NH]CN(*)* +544,Methylendiamines (3),"[!$([C,S]=O)][NH][CX4][NH][!$([C,S]=O)]",*[NH]C[NH]* +545,N-Acetoxy amines and their thio analogues,"[#7][#8][C,S]=O",NO*=O +546,α-Halogen substituted N-heterocycles,"[F,Br,Cl,I]-cn",*cn +547,Activated haloaromatics,"[F,Cl,Br,I][$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",** +548,Compounds containing three bonded nitrogen atoms,[NX1]~[NX2]~[NX2],N~N~N +549,Benzyl ammoniums,cC[NX4+],cC[N+] +550,α-Carbonyl ammoniums,C(=O)[#6][NX4+],[N+]CC=O +551,Cations,"[#6+,#17+,#53+,#15+,#16+]",* +552,Enamines,[#6][CX3](!@N)=[CX3][#6],CC=C(C)~N +553,Halogen-bonded heteroatoms,"[!#1&!#6][F,Cl,Br,I]",** +554,Cumulated double bonds,"[C,N]=C=[C,O,N,S]",*=C=* +555,Acetoxy group attached to the aromatic nitrogen,C(=O)Onnn,nnnOC=O +556,Singel acyclic N-N bonds,[#7]!@-N,N~N +557,Activated double bonds (1),[C!H0]=C(C#N)C(=O),C=C(C=O)C#N +558,Activated double bonds (2),[!c][C!H0]=CC=O,*C=CC=O +559,Activated double bonds (3),"[C!H0]=C[S,N]=O",C=C*=O +560,N-Acyl substituted azoheterocycles,nC(=O)[#6],CC(n)=O +561,Singel acyclic N-S bonds,[NR0]-[SR0!v6],NS +562,Acetoxy group attached to the substituted aromatic ring,"C(=O)O[$(aa[Nv4,S!v2]),$(aaa[Nv4,S!v2]),$(aaaa[Nv4,S!v2])]",*OC=O +563,"Oxetanes, thietanes","C1[O,S]CC1",*1CCC1 +564,Trihalomethyl ketones,"CC(=O)C([F,Cl,Br,I])([F,Cl,Br,I])[F,Cl,Br,I]",*C(*)(*)C(C)=O +565,Phosphonates,[#6]P(=O)O[#6],COP(C)=O +566,Phosphorus containing compounds ,"NP(=[N,O,S])",*=PN +567,p-Quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +568,o-Quinones,O=C1C(=O)C=CC=C1,O=C1C=CC=CC1=O +569,"C, N, O, P and S atoms in unusual valence states","[#6!v4+0,#7!v3+0,#8!v2+0,#15!v3!v5+0,#16!v2!v4!v6+0]",* +570,Sulfurous acid esters,[!#1]OS(=O)O,*OS(O)=O +571,Heteroatom-bonded thiocarbonyls,"C(=S)[O,S,N]",*C=S +572,Thiocarboxylic acids and their derivatives,[CR0](=O)S,O=CS +573,Thiocarbonyls,C(=S)[!#1!H0],*C=S +574,"N-Acetoxy-N,N-dicarbonyl compounds",C(=O)N(C(=O))OC=O,O=CON(C=O)C=O +575,Trifluoromethyl sulfinyls,FC(F)(F)S(=O),O=SC(F)(F)F +576,Non-threevalent nitrogen double-bonded to oxygen,[#6!c][N!v3]=O,CN=O +577,Anthracenes,c12ccccc1cc3ccccc3c2,c1ccc2cc3ccccc3cc2c1 +578,Double acyclic N=N and N=S bonds,"[NR0,SR0]=[NR0]",*=N +579,β-Aminonaphtalenes,c1(cc(N)cc2)c2cccc1,Nc1ccc2ccccc2c1 +580,Dialkyl(aryl) phosphorus containing compounds,[#6]P[#6],CPC +581,"Iodosos, chlorosos","[Cl,I]=O",*=O +582,Acid grops,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +583,Phosphocyanates,PC#N,N#CP +584,α-Hydroxy nitriles,N#CC[OH],N#CC[OH] +585,α-Diketones,[CX3R0](=O)[CX3R0](=O),O=CC=O +586,Singel acyclic N-O bonds,[NR0v3]-[OR0],NO +587,Activated double bonds (4),C=C(C#N)(C#N),C=C(C#N)C#N +588,Nitrites,[!#1]ON=O,*ON=O +589,Nitroso compounds,[NX2]=O,N=O +590,"Any atoms except organogens, halogens, P, S, K, Na, Mg, Ca",[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +591,Double P=S and P=C bonds,"P=[S,#6]",*=P +592,Pentafluorobenzenes,c1c(F)c(F)c(F)c(F)c1(F),Fc1cc(F)c(F)c(F)c1F +593,Phenanthrenes,c12ccccc1ccc3ccccc23,c1ccc2c(c1)ccc1ccccc12 +594,p-Aminoanilines,c1([NH2])ccc(!@[Nv3])cc1,[NH2]c1ccc(~N)cc1 +595,Phosphorus derivatives,[P!v5],P +596,Conjugated olefins,[CR0]=[CR0][CR0]=[CR0][CR0]=[CR0][CR0]=[CR0],C=CC=CC=CC=C +597,Carboxylic acid esters,[CX4]C(=O)O[#6][!#1],*COC(C)=O +598,"N,N-Dialkyl aniline derivatives (1)","[CX4][NX3]([CX4])c1cc([$([CX4]),$(O[CX4][CX4])])c([#7])[cH]c1",*c1cc(N(C)C)c[cH]c1N +599,"N,N-Dialkyl aniline derivatives (2)",[CX4][NX3]([CX4])c1c[cH]c([#7])[cH]c1,CN(C)c1c[cH]c(N)[cH]c1 +600,"N,N-Dialkyl aniline derivatives (3)",[CX4][NX3]([CX4])c1ccc(C=C)cc1,CN(C)c1ccc(C=C)cc1 +601,p-Alkoxy-N-alkyl anilines,[CX4][NH]c1ccc(O[CX4])cc1,C[NH]c1ccc(OC)cc1 +602,"p-Alkoxy-N,N-dialkyl anilines",[CX4]N([CX4])c1ccc(O[CX4])cc1,COc1ccc(N(C)C)cc1 +603,"N,N-Dialkyl aniline derivatives (4)","[CX4]N([CX4])c1ccc([CX4][$([OH]),$(C=[C!H0]),$(N[CX4])])cc1",*Cc1ccc(N(C)C)cc1 +604,"N,N-Dialkyl aniline derivatives (5)","[CX4]N([C!H0])c1[cH][cH]c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH][cH]1 +605,"N,N-Dialkyl aniline derivatives (6)","[CX4]N([C!H0])c1[cH]c([CX4])c([$([C!H0!H1]),$([C!H0][C!H0])])[cH][cH]1",*c1[cH][cH]c(N(C)C)[cH]c1C +606,Phosphoric anhydrides,P(=O)OP(=O),O=POP=O +607,Five-membered heterocycles (1),"C1(=C)C(=O)[#7,#8,#15,#16]N=C1",C=C1C=N*C1=O +608,Thioxo-thiazolidinones,C1(=S)NC(=O)C(=[#6])S1,C=C1SC(=S)NC1=O +609,Six-membered heterocycles,"[#7,#8,#15,#16]~C1~[#7,#8,#15,#16]~C[#7,#8,#15,#16][CX3](=[#7,#8,#15,#16])[CX3]1(=[C!H0])",*~C1C(=C)C(=*)*C~*~1 +610,Glutarimides,C1CC(=O)NC(=O)C1,O=C1CCCC(=O)N1 +611,Aliphatic chain,[CD1][CD2][CD2][CD2][CD2][CX4],CCCCCC +612,o-Substituted phenols (1),[OH]c1c(C=NN)cccc1,NN=Cc1ccccc1[OH] +613,p-Substituted phenols,[OH]c1ccc(C=NN)cc1,NN=Cc1ccc([OH])cc1 +614,"1,2-Diimines, 1,2-diketones and their thio- and phospho-analogues","[#6][#6](=[#7,#8,#15,#16])[#6](=[#7,#8,#15,#16])[#6,Sv6]",*C(=*)C(=*)C +615,Indolones,O=C1[#7]c2ccccc2C1=N[#7],NN=C1C(=O)Nc2ccccc21 +616,NH-Indoles,"[nH]1c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1[nH]c2ccc[cH]c2c1C +617,N-Alkyl substituted indoles,"n1([CH2])c([$([CH2]),$([C!H0]N),$([CD3]([CH2])[NH][CH2]),$([CD3]([CH2])[CD2][NH][CH2]),$([#6]=,:[#7,#8,#15,#16])])c([CX4!H0])c2[cH]cccc12",*c1c(C)c2[cH]cccc2n1[CH2] +618,Macrocycles,"[*r10,*r11,*r12,*r13,*r14,*r15,*r16,*r17,*r18,*r19,*r20,*r21,*r22,*r23,*r24,*r25,*r26,*r27,*r28,*r29,*r30]",* +619,o-Substituted phenols (2),[OH]c1c([CX4][#7])cccc1,NCc1ccccc1[OH] +620,N-Allophanoylamides and their thio analogues,"NC(=[O,S])NC(=[O,S])NC=[O,S]",*=CNC(=*)NC(=*)N +621,Tetrahydrofuranyltetrahydropyrans,C1COC(C1)C1CCCCO1,C1CCC(C2CCCO2)OC1 +622,Octahydroisoindolones,[C!H0]1NC(=O)C2CCCCC12,O=C1NCC2CCCCC21 +623,N-Phenylpyrrole derivatives,N1(c2[!#1]cccc2)C([CX4])=C[C!H0]=C1[CX4],CC1=CC=C(C)N1c1cccc*1 +624,"Quinones, quinone-(di)imines and their thio- and phospho-analogues","[#7,#8,#15,#16]=[#6]1-,:[#6]=,:[#6]-,:[#6](=[#7,#8,#15,#16])-,:[#6]=,:[#6]1",*=C1C=CC(=*)C=C1 +625,Five-membered heterocycles (2),"[#7]=C1S[CH]=C([$([CH2]),$(c:c)])N1",*C1=[CH]SC(=N)N1 +626,Five-membered heterocycles (3),"[#7]=C1SC([$([CH2]),$(C=O)])=C([$([CH2]),$(c:c)])N1",*C1=C(*)SC(=N)N1 +627,Tert-butyl carbon atom,c[CX4](c)c,cC(c)c +628,Acethylenes,"[CH2,CH3]C#C[CH2,CH3]",*C#C* +629,α-Halonitriles,"[F,Cl,Br,I][CX4][CX2]#[NX1]",*CC#N +630,Azide tautomers,[#6]-[NX2-][NX2+]#[NX1;0],C[N-][N+]#N +631,Benzthiozolium like compounds,"[#7,#8,#16]1-,:[#6]=,:[#6]-,:[#7+]2=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6]21",*1C=C[N+]2=**=**=C12 +632,Cyanates,"[NX2]=[CX2]=[OX1,SX1]",*=C=N +633,Di-carbonyls,"[#1,#6][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(*)=O +634,Haloalkyl,"[C!H0]([#1,#6,#7,#8,#16])[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])[Cl,Br,I]",*CC(*)(*)* +635,"Haloalkyl group attached to S, N or O atoms","[CX4]([#1,Cl,Br,I])([#1,Cl,Br,I])([Cl,Br,I])[#7,#8,#16]",*C(*)(*)* +636,Haloethylenes,"[CX3!H0]=[CX3]([#1,Cl,Br,I])[Cl,Br,I]",*C(*)=C +637,Halopyridines,"c1([F,Cl,Br,I])n[c,n][c,n][c,n][c,n]1",*c1*:*:*:*n1 +638,Heptanes,"[CH3][CH2][CH2][CH2][CH2][CH2][CH2,CH3]",*[CH2][CH2][CH2][CH2][CH2][CH3] +639,N-Oxides (six-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]1)]",* +640,N-Oxides (five-membered rings),"[$([OX1-][#7+]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1),$([OX1]=[#7v5]1=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6,#7,#8,#16]1)]",* +641,Phosphorus cations,[#15+],[PH4+] +642,Peroxide like compounds,"O[F,Cl,Br,I]",*O +643,Phosphates,[Pv5X4](=[OX1])([OX2])([OX2])[#6],CP(O)(O)=O +644,Double P=O bonds,[#15]=O,O=P +645,Pyridinium like compounds,"[#6][#7+]1=,:[#6]-,:[#6,#7]=,:[#6]-,:[#6,#7]=,:[#6]1",C[N+]1=C*=C*=C1 +646,Quinolizinium like compounds,"[#6,#7]1=,:[#6,#7]-,:[#6,#7]=,:[#7+]2-,:[#6,#7]=,:[#6,#7]-,:[#6,#7]=,:[#6,#7]-,:[#6]2=,:[#6,#7]1",*1=**=[N+]2*=**=*C2=*1 +647,Sulfates,"[Sv6X4](=[OX1])(=[OX1])([#8])[#6,#8]",*S(O)(=O)=O +648,Thio aldehydes,"[#6,#1][CX3]([H])=[SX1]",*C([H])=S +649,Thio halogens,"[#16][F,Cl,Br,I]",*S +650,Thioalcohols,"[#6&!$(C(=[OX1,SX1,NX2]))][SX2H1]",C[SH] +651,Thiozolium like compounds,"[#6][#7+]1=,:[#6]-,:[#7,#8,#16]-,:[#6]=,:[#6]1",C[N+]1=C*C=C1 +652,Acyl Halides,"[Br,Cl,F,I][CX3](=[OX1])[#1,*&!$([OH1])&!$([SH1])]",*C(*)=O +653,Sulphonyl Halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +654,Alkyl Halides,"[CX4][F,Cl,Br,I]",*C +655,Activated Halides,"[$(c([F,Cl,Br,I])c[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])aac[$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])]),$(c([F,Cl,Br,I])n),$(c([F,Cl,Br,I])aan)]",* +656,Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +657,Aldehydes (including aminoformyl moieties),"[$([#1,#6][CX3]([H])=[OX1]),$([#7]([#1,#6])([#1,#6])[CX3H1]=[OX1])]",* +658,Nitrosos,[NX2]=[OX1],N=O +659,Picrates,"c1([OH1,O-])c([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])cc1([$([NX3](=[OX1])=[OX1]),$([NX3+](=[OX1])[O-])])",*c1cc(*)c(*)c(*)c1 +660,Perchlorates (periodates),"[$([Clv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-]),$([Iv7X4](=[OX1])(=[OX1])(=[OX1])[OX2,O-])]",* +661,Simple anilines and phenols,"[$(c1([NX3]([#1,#6])[#1,#6])ccccc1),$(c1([OH1])ccccc1)]",* +662,Vinyl ketones (Michael acceptors),[CX3]([!R])([!R])=[CX3][CX3](=[OX1])[!$([OH1])!$([OX2][CH2])!$([NH2])!$([CX2]#[NX1])!a],*C(=O)C=C(*)* +663,Metals,[!#1;!#6;!#7;!#8;!#9;!#11;!#12;!#15;!#16;!#17;!#19;!#20;!#35;!#53],* +664,Non-organic chemistry atoms,[!#6!#1!#7!#8!#9!#17!#35!#53!#15!#14!#16],* +665,Atoms not supported in ALOGPS program,[!#1!#6!#7!#8!#16!#15!#9!#17!#35!#53],* +666,Perfluoroalkylated compounds (PFCs),C(F)(F)C(F)(F),FC(F)C(F)F +667,Carbonyl compouns: aldehydes or ketones,"[$([H][CX3]([#1,#6])=[OX1]),$([#6&!$(C#N)][CX3](=[OX1])[#6&!$(C#N)])]",* +668,Thiocarbonyl compounds: thioaldehydes or thioketones,"[$([#1,#6][#6X3](=[SX1])[#1,#6]),$([#6]=[CX2]=[Sv2X1])]",* +669,Thioaldehydes,"[#1][CX3]([#1,#6])=[SX1]",*C([H])=S +670,Thioketones,[#6&!$(C#N)][CX3](=[SX1])[#6&!$(C#N)],CC(C)=S +671,Hydrazones,"[CX3]([#1,#6])([#1,#6])=[NX2][#7X3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)* +672,Semicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=O)N(*)* +673,Thiosemicarbazones,"[#1,#6][CX3]([#1,#6])=[NX2][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NN(*)C(=S)N(*)* +674,Oximes,"[#1,#6][CX3]([#1,#6])=[NX2][OH1]",*C(*)=N[OH] +675,Oxime ethers,"[#1,#6][CX3]([#1,#6])=[NX2][OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(*)=NOC +676,Ketene acetal derivatives,"[#1,#6][CX3]([#1,#6])=[CX3]([!#6!#1])[!#6!#1]",*C(*)=C(*)* +677,Carbonyl hydrates,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OH1]",[OH]*[OH] +678,Hemiacetals / Hemiketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OH1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*[OH] +679,Acetals / Ketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",CO*OC +680,Hemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([OX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,*])[#1,*]",*O*N(*)* +681,Thiohemiaminals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#1,#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[NX3]([#1,*])[#1,*]",*S*N(*)* +682,Thioacetals / Thioketals,"[CH2,$([CH1][#6]),$([CX4]([#6])[#6])]([SX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)])[SX2,OX2][#6&!$([CX3]=[OX1,SX1,NX2])&!$(C#N)]",C**SC +683,Enols,"[CX3]([#1,#6])([#1,#6])=[CX3]([OH1])[#1,#6]",*C(*)=C(*)[OH] +684,Enolethers,"[CX3]([#1,#6])([#1,#6])=[CX3]([OX2][#6&!$([CX3]([OX2])=[OX1,SX1,NX2,C])])[#1,#6]",*C(*)=C(*)OC +685,Hydroxy compounds: alcohols or phenols,"[#6&!$([CX4]([OH1])[#8,#16,#7,#15])&!$([CX3]([OH1])=[OX1,SX1,NH2,C])][OH1]",C[OH] +686,Alcohols,"[$([CX4][OH1])&!$(C([OH1])[#7,#8,#15,#16,F,Cl,Br,I])]",* +687,Primary alcohols,"[$([#6][CH2][OH1]),$([CH3][OH1])]",* +688,Secondary alcohols,[OH1][CX4H1]([#6])[#6],C[CH](C)[OH] +689,Tertiary alcohols,[CX4]([OH1])([#6])([#6])[#6],CC(C)(C)[OH] +690,"1,2-Diols","[CX4]([OH1])([#1,#6])([#1,#6])[CX4]([OH1])([#1,#6])([#1,#6])",*C(*)([OH])C(*)(*)[OH] +691,"1,2-Aminoalcohols","[CX4]([#1,#6])([#1,#6])([OH1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([CX4][CX4][OH1])[#6&!$([CX3]=[OX1,SX1,NX2,C])])]",*C(*)(*)C(*)(*)[OH] +692,Phenols,c[OH1],c[OH] +693,Diphenols,"[$(c([OH1])c([OH1])),$(c([OH1])[aR1]c([OH1])),$(c1([OH1])aac([OH1])aa1)]",* +694,Enediols,"[CX3]([#1,#6])([OH1])=[CX3]([#1,#6])([OH1])",*C([OH])=C(*)[OH] +695,Dialkylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2][CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))]",COC +696,Alkylarylethers,"[CX4&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))][OX2]c",COc +697,Diarylethers,c[OX2&!$([OX2r3])]c,cOc +698,Hydroperoxides,"[#1,#6][OX2][OX2H1]",*O[OH] +699,Hydrazine derivatives,"[$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])][$([NX4]([#1,#6])([#1,#6])([#1,#6])),$([NX3]([#1,#6])([#1,#6])),$([NX2]=[#1,#6])]",** +700,Primary aliphatic amines,"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +701,Primary aromatic amines,[NX3H2]c,c[NH2] +702,Secondary aliphatic amines,"[NX3H1]([CX4&!$([CX4]([NX3H1])[O,S,N,P])])[CX4&!$([CX4]([NX3H1])[O,S,N,P])]",C[NH]C +703,Secondary mixed amines (aryl alkyl),"c[NX3H1][CX4&!$([CX4]([NX3H1])[O,N,S,P])]",c[NH]C +704,Secondary aromatic amines,[NX3H1](c)c,c[NH]c +705,Tertiary aliphatic amines,"[NX3]([CX4&!$([CX4]([NX3])[O,S,N,P])])([CX4&!$([CX4]([NX3])[O,S,N,P])])[CX4&!$([CX4]([NX3])[O,S,N,P])]",CN(C)C +706,Tertiary mixed amines (aryl alkyl),"c[NX3]([CX4&!$([CX4]([NX3])[O,N,S,P])])[c,CX4&!$([CX4]([NX3]c)[O,S,N,P])]",*N(c)C +707,Quaternary ammonium salts,"[NX4,NX4+]([#6])([#6])([#6])[#6]",C*(C)(C)C +708,"Halogen derivatives (alkyl, alkenyl, aryl)","[CX4,CX3,c;!$([#6]=[OX1])][F,Cl,Br,I]",** +709,Aryl fluorides,aF,*F +710,Aryl chlorides,aCl,*Cl +711,Aryl bromides,aBr,*Br +712,Aryl iodides,aI,*I +713,Organolithium compounds,[Li][#6],[Li]C +714,Organomagnesium compounds,[Mg][#6],C[Mg] +715,Carboxylic acid derivatives,"[#1,#6][CX3](=[OX1])[!#1!#6!$([SH1,SX2])]",*C(*)=O +716,Carboxylic acid salts,"[#1,#6][CX3](=[OX1])[OX1-]",*C(=O)[O-] +717,Carboxylic acid amides,"[#1,#6][CX3](=[OX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=O)N(*)* +718,Carboxylic acid primary amides,"[#1,#6][CX3](=[OX1])[NX3H2]",*C([NH2])=O +719,Carboxylic acid secondary amides,"[#1,#6][CX3](=[OX1])[NX3H1][#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)[NH]C +720,Carboxylic acid tertiary amides,"[#1,#6][CX3](=[OX1])[NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",*C(=O)N(C)C +721,Lactams,"[#6R][CX3R](=[OX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=O +722,Carboxylic acid hydrazides,"[$([#6,#1][#6X3](=[OX1])[#7X3&!$([#7X3]([*]=[OX1,SX1])[#7X3]([*]=[OX1,SX1]))][#7X3]),$(C1(=O)[NX3][NX3]C(=O)cc1)]",* +723,Carboxylic acid azides,"[#1,#6][CX3](=[OX1])[$([NX2]=[NX2+]=[NX1-]),$([NX2]=[NX2+]=N),$([NX2-]-[NX2+]#[NX1])]",*C(*)=O +724,Hydroxamic acids,"[#1,#6][CX3](=[OX1])[NX3][OH1]",*C(=O)N[OH] +725,Carboxylic acid amidines,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,N])]",*N=C(*)N(*)* +726,Carboxylic acid amidrazones,"[#1,#6][NX2]=[CX3]([#1,#6])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#1,#6&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)N(*)N(*)* +727,Nitriles,"[#1,#6&!$([CX3]=[OX1,SX1])][CX2]#[NX1]",*C#N +728,Acyl fluorides,"[#1,#6][CX3](=[OX1])F",*C(=O)F +729,Acyl chlorides,"[#1,#6][CX3](=[OX1])Cl",*C(=O)Cl +730,Acyl bromides,"[#1,#6][CX3](=[OX1])Br",*C(=O)Br +731,Acyl iodides,"[#1,#6][CX3](=[OX1])I",*C(=O)I +732,Acyl cyanides,"[#1,#6][CX3](=[OX1])[CX2]#[NX1]",*C(=O)C#N +733,Imido esters,"[#1,#6][CX3](=[NX2][#1,#6])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*N=C(*)OC +734,Thiocarboxylic acid derivatives,"[$([#1,#6][CX3](=[SX1])[!#1!#6]),$([#1,#6][CX3](=[OX1])[SX2])]",* +735,Thiocarboxylic acids,"[$([#1,#6][CX3](=[SX1])[OH1,SH1]),$([#1,#6][CX3](=[OX1])[SH1])]",* +736,Thiocarboxylic acid esters,"[$([#1,#6][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#1,#6][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +737,Thiolactones,"[$([#6R][CX3R](=[SX1])[OX2R,SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])]),$([#6R][CX3R](=[OX1])[SX2R][#6R&!$([CX3R]=[OX1,SX1,NX2])])]",* +738,Thiocarboxylic acid amides,"[#1,#6][CX3](=[SX1])[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX1])])[#1,#6&!$([CX3]=[OX1,SX1,NX1])]",*C(=S)N(*)* +739,Thiolactams,"[#6R][CX3R](=[SX1])[NX3R]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])[#6R&!$([CX3R]=[OX1,SX1,NX2])]",*N(C)C(C)=S +740,Imidothioesters,"[#1,#6][CX3](=[NX2][#1,#6])[SX2][C&!$([CX3]=[OX1,SX1,NX2])]",*N=C(*)SC +741,Oxohetarenes,"[$(c(=[OX1])[$(n[#1,#6]),o,s]),$(c(=[OX1])a[$(n[#1,#6]),o,s]),$(c(=[OX1])aa[$(n[#1,#6]),o,s]),$(c(=[OX1])aaa[$(n[#1,#6]),o,s])]",* +742,Thioxohetarenes,"[$(c(=[SX1])[$(n[#1,#6]),o,s]),$(c(=[SX1])a[$(n[#1,#6]),o,s]),$(c(=[SX1])aa[$(n[#1,#6]),o,s]),$(c(=[SX1])aaa[$(n[#1,#6]),o,s])]",* +743,Iminohetarenes,"[$(c(=N)[$(n[#1,#6]),o,s]),$(c(=N)a[$(n[#1,#6]),o,s]),$(c(=N)aa[$(n[#1,#6]),o,s]),$(c(=N)aaa[$(n[#1,#6]),o,s])]",* +744,Orthocarboxylic acid derivatives,"[CX4&!$([CX4]([F,Cl,Br,I])([F,Cl,Br,I])([F,Cl,Br,I]))]([#1,#6&!$([CX3]=[OX1,SX1,NX2])])([!#1!#6])([!#1!#6])[!#1!#6]",*C(*)(*)* +745,Carboxylic acid orthoesters,"[#1,#6][CX4]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])]",*C(OC)(OC)OC +746,Carboxylic acid amide acetals,"[CH1,$([CX4][#6])]([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])([OX2][#6&!$([CX3]=[OX1,SX1,NX2,C])])[NX3]([#1,*])[#1,*]",*N(*)*(OC)OC +747,Carboxylic acid imides,[CX3](=[OX1])[NX3][CX3](=[OX1]),O=CNC=O +748,Carboxylic acid unsubstituted imides,[CX3](=[OX1])[NX3H1][CX3](=[OX1]),O=C[NH]C=O +749,Carboxylic acid substituted imides,[CX3](=[OX1])[NX3H0][CX3](=[OX1]),O=CNC=O +750,CO2 derivative (general),"[$([Cv4X4]([!#1!#6])([!#1!#6])([!#1!#6])[!#1!#6]),$([CX3](=[!#1!#6])([!#1!#6])[!#1!#6]),$([CX2](=[!#1!#6])=[!#1!#6]),$([CX2](#[!#1!#6])[!#1!#6])]",* +751,Carbonic acid derivatives,"[$([CX3](=[OX1])([!#1!#6])[!#1!#6])&!$([CX3](=[OX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +752,Carbonic acid monoesters,"[OH1][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)[OH] +753,Carbonic acid diesters,"[#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",COC(=O)OC +754,Carbonic acid ester halides,"[#6][OX2][CX3](=[OX1])[F,Cl,Br,I]",*C(=O)OC +755,Thiocarbonic acid derivatives,"[$([CX3](=[SX1])([!#1!#6])[!#1!#6])&!$([CX3](=[SX1])([#7,#16X2,#15,#5])[#8X2,#16X2,#7,#15,#5]),$([CX3](=[OX1])([!#1!#6])[SX2])&!$([CX3](=[OX1])([#7,#15,#5])[#8X2,#16X2,#7,#15,#5])]",* +756,Thiocarbonic acid monoesters,"[$([OH1,SH1][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([OH1][CX3](=[OX1])[SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([SH1][CX3](=[SX1,OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +757,Thiocarbonic acid diesters,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[OX2,SX2][#6&!$([CX3]=[OX1,SX1,NX2])])]",* +758,Thiocarbonic acid ester halides,"[$([#6&!$([CX3]=[OX1,SX1,NX2])][OX2,SX2][CX3](=[SX1])[F,Cl,Br,I]),$([#6&!$([CX3]=[OX1,SX1,NX2])][SX2][CX3](=[OX1])[F,Cl,Br,I])]",* +759,Carbamic acid derivatives,"[NX3]([#1,*])([#1,*])[CX3](=[OX1])[!#1!#6!#16!$([Pv5])]",*C(=O)N(*)* +760,Carbamic acid,[OH1][CX3](=[OX1])[NX3],NC(=O)[OH] +761,Carbamic acid esters (urethanes),"[#6][OX2][CX3](=[OX1])[NH2,NH1,NX3]",*C(=O)OC +762,Carbamic acid halides,"[F,Cl,Br,I][CX3](=[OX1])[NX3]",*C(N)=O +763,Thiocarbamic acid derivatives,"[$([NX3&!$([NX3]([CX3]=[SX1])[CX3]=[OX1,SX1,NX2])][CX3](=[SX1])[!#1!#6!#7!$([Pv5])]),$([NX3&!$([NX3]([CX3]=[OX1])[CX3]=[OX1,SX1,NX2])][CX3](=[OX1])[SH1,SX2])]",* +764,Thiocarbamic acids,"[$([OH1,SH1][CX3](=[SX1])[NX3]),$([SH1][CX3](=[OX1])[NX3])]",* +765,Thiocarbamic acid esters,"[$([#6][OX2,SX2][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])]),$([#6][SX2][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[CX3]=[OX1,SX1])])]",* +766,Thiocarbamic acid halides,"[F,Cl,Br,I][CX3](=[SX1])[NX3]",*C(N)=S +767,Isoureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([OX2])=[NX2][#1,#6]",*N=C(O)N(*)* +768,Isothioureas,"[NX3&!$([NX3]([CX3]=[OX1,SX1,NX2])([CX3]=[OX1,SX1,NX2]))]([#1,#6])([#1,#6])[CX3]([S&!$([SX2]([CX3]=N)C=C)])=[NX2][#1,#6]",*N=C(S)N(*)* +769,Guanidines,"N[CX3](=[NX2][#1,#6])N",*N=C(N)N +770,Semicarbazides,"[$([NX3][CX3](=[OX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[OX1])[NX3]N=C)]",* +771,Thiosemicarbazides,"[$([NX3][CX3](=[SX1])[NX3&!$([NX3]([CX3]=[OX1,SX1])[NX3][CX3]=[OX1,SX1])][NX3])&!$([NX3][CX3](=[SX1])[NX3]N=C)]",* +772,Isonitriles,"[#6&!$([CX3]=[OX1,SX1])][$([NX2+]#[CX1-]),$([NX2]#[CX1])]",*C +773,Sulfuric acid derivatives,[!#1!#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(*)(=O)=O +774,Sulfuric acid,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])[OX2,O-]",*S(*)(=O)=O +775,Sulfuric acid monoesters,"[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(=O)(=O)OC +776,Sulfuric acid diesters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])[OX2][#6],COS(=O)(=O)OC +777,Sulfuric acid amide esters,[#6][OX2][Sv6X4](=[OX1])(=[OX1])N,COS(N)(=O)=O +778,Sulfuric acid amides,"[OH1,O-][Sv6X4](=[OX1])(=[OX1])N",*S(N)(=O)=O +779,Sulfuric acid diamides,N[Sv6X4](=[OX1])(=[OX1])N,NS(N)(=O)=O +780,Sulfuryl halides,"[!#1!#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(*)(=O)=O +781,Sulfonic acid derivatives,[#6][Sv6X4](=[OX1])(=[OX1])[!#1!#6],*S(C)(=O)=O +782,Sulfonic acids,"[#6][Sv6X4](=[OX1])(=[OX1])[OH1,O-]",*S(C)(=O)=O +783,Sulfonyl halides,"[#6][Sv6X4](=[OX1])(=[OX1])[F,Cl,Br,I]",*S(C)(=O)=O +784,Sulfones,"[#6][Sv6X4](=[OX1,SX1,NX2])(=[OX1,SX1,NX2])[#6]",*=S(=*)(C)C +785,Sulfinic acid derivatives,[#6][Sv4X3](=[OX1])[!#1!#6],*S(C)=O +786,Sulfinic acids,"[#6][Sv4X3](=[OX1])[OH1,O-]",*S(C)=O +787,Sulfinic acid esters,[#6][Sv4X3](=[OX1])[OX2][#6],COS(C)=O +788,Sulfinic acid halides,"[#6][Sv4X3](=[OX1])[F,Cl,Br,I]",*S(C)=O +789,Sulfinic acid amides,"[#6][Sv4X3](=[OX1])[NX3&!$([NX3][CX3]=[OX1,SX1,NX2])]",CS(N)=O +790,Sulfenic acid derivatives,[#6][Sv2X2][!#6!#1!S],*SC +791,Sulfenic acids,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OH1]",CS[OH] +792,Sulfenic acid esters,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][OX2][#6]",COSC +793,Sulfenic acid halides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][F,Cl,Br,I]",*SC +794,Sulfenic acid amides,"[#6&!$([CX3]=[SX1,OX1,NX2])][Sv2X2][NX3]([#6&!$([CX3]=[OX1,SX1,NX2])])[#6&!$([CX3]=[OX1,SX1,NX2])]",CSN(C)C +795,Alkylthiols,"[C&!$([CX3]=[OX1,SX1,N,C])&!$(C#N)][Sv2H1]",C[SH] +796,Thiophenols,c[Sv2H1],c[SH] +797,Phosphoric acid derivatives,"[OX1]=[Pv5X4]([H,!#6!$([SX2])])([H,!#6!$([SX2])])[H,!#6!$([SX2])]",*P(*)(*)=O +798,Phosphoric acids,[OX1]=[Pv5X4]([OH1])([O])[O],OP(O)(=O)[OH] +799,Phosphoric acid esters,[OX1]=[Pv5X4]([OX2][#6])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(=O)OC +800,Phosphoric acid halides,"[OX1]=[Pv5X4]([F,Cl,Br,I])([!#6!$([SX2])])[!#6!$([SX2])]",*P(*)(*)=O +801,Phosphoric acid amides,[OX1]=[Pv5X4]([NX3])([!#6!$([SX2])])[!#6!$([SX2])],*P(*)(N)=O +802,Thiophosphoric acid derivatives,"[$([SX1]=[Pv5X4]([H,!#6])([H,!#6])[H,!#6]),$([OX1]=[Pv5X4]([SX2])([H,!#6])[H,!#6])]",* +803,Thiophosphoric acids,"[$([SX1]=[Pv5X4]([OH1,SH1])([O,S])[O,S]),$([OX1]=[Pv5X4]([SH1])([O,S])[O,S])]",* +804,Thiophosphoric acid esters,"[$([SX1]=[Pv5X4]([OX2,SX2][#6])([!#6])[!#6]),$([OX1]=[Pv5X4]([SX2][#6])([!#6])[!#6])]",* +805,Thiophosphoric acid halides,"[$([SX1]=[Pv5X4]([F,Cl,Br,I])([!#6])[!#6]),$([OX1]=[Pv5X4]([F,Cl,Br,I])([SX2,SH1])[!#6])]",* +806,Thiophosphoric acid amides,"[$([SX1]=[Pv5X4]([NX3])([!#6])[!#6]),$([OX1]=[Pv5X4]([NX3])([SX2,SH1])[!#6])]",* +807,Phosphonic acid derivatives,[OX1]=[Pv5X4]([#6])([!#6])[!#6],*P(*)(C)=O +808,Phosphonic acids,[OX1]=[Pv5X4]([#6])([OH1])O,CP(O)(=O)[OH] +809,Phosphonic acid esters,[OX1]=[Pv5X4]([#6])([OX2][#6])[!#6],*P(C)(=O)OC +810,Phosphines,[Pv3X3]([#6])([#6])[#6],CP(C)C +811,Phosphinoxides,[Pv5X4](=[OX1])([#6])([#6])[#6],CP(C)(C)=O +812,Boronic acid derivatives,[Bv3X3]([#6])([!#6])[!#6],*B(*)C +813,Boronic acids,"[BX3]([#6])([OH1,SH1])[O,S]",*B(*)C +814,Boronic acid esters,"[BX3]([#6])([OX2][#6])[H,!#6]",*B(C)OC +815,Aromatic compounds,[a!r0],* +816,Heterocyclic compounds,[*R]~[*R&!#6]~[*R],*~*~* +817,Aromatic heterocyclic compounds,[a!#6!r0],* +818,α-Aminoacids,"[OH1][CX3](=[OX1])[CX4]([#1,#6])([#1,#6])[NH2,$([NH1]([#6])[#6])&!$([NH1](CC(=O)[OH1])[CX3]=[OX1,SX1])]",*C(*)(*)C(=O)[OH] +819,α-Hydroxyacids,"[OH1][CX3](=[OX1])[CX4]([OH1])[#1,#6]",*C([OH])C(=O)[OH] +820,"1,2-Diamines","[NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])[CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CCN(*)* +821,"1,2-Dithiols","[CX4]([SH1])([#1,#6])([#1,#6])[CX4]([SH1])([#1,#6])([#1,#6])",*C(*)([SH])C(*)(*)[SH] +822,"1,2-Aminothiols","[SH1][CX4][CX4][NX3]([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])([#1,#6&!$([CX3]=[OX1,SX1,NX2,C])])",*N(*)CC[SH] +823,α-Oxoacids,"[OH1][CX3](=[OX1])[CX3](=[OX1])[#1,#6]",*C(=O)C(=O)[OH] +824,"α, β-Unsaturated carboxylic acids",[OH1][CX3](=[OX1])[CX3]=[CX3],C=CC(=O)[OH] +825,Dithiophenols,"[$(c([SH1])c([SH1])),$(c([SH1])[aR1]c([SH1])),$(c1([SH1])aac([SH1])aa1)]",* +826,Aminothiophenols,"[$(c([SH1])c[NX3]([#1,#6])[#1,#6]),$(c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]),$(c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1)]",* +827,Aryl halides,"a[F,Cl,Br,I]",** +828,Primary amines,"[NX3H2][c,CX4&!$([CX4]([NH2])[O,N,S,P])]",*[NH2] +829,Secondary 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+1063,Hzone_anil_di_alk,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6H]=[#7][#7][$([#6](=O)[CH2]Scn),$([#6](=O)[CH2]aan),$([#6](=O)cc[OH1]),$(cn),$([CH2][#6!H0][OH1])])[cH][cH]1",*NN=[CH]c1[cH][cH]c(N(*)*)[cH][cH]1 +1064,Hzone_acyl_naphthol,[cH]1[cH][cH][cH]c2c1[cH]c(C(=[OX1])[N!H0]N=C)c([OH1])[cH]2,C=NNC(=O)c1[cH]c2[cH][cH][cH][cH]c2[cH]c1[OH] +1065,Keto_keto_beta_A,c1ccc2C(=[OX1])[CX4]C(=[OX1])c2c1,O=C1CC(=O)c2ccccc21 +1066,Keto_keto_beta_zone,"cc[N!H0]N=C([CH2,CH3])[CH2]C([CH2,CH3])=N[N!H0]cc",*C([CH2]C(*)=NNcc)=NNcc +1067,Cyano_ene_amine_A,C(C#[NX1])(C#[NX1])C([NH2])=CC#[NX1],N#CC=C([NH2])C(C#N)C#N +1068,Cyano_pyridone_A,"[#6]1(=[SX1])-,:[#7!H0]-,:*=,:*-,:*=,:[#6]1C#[NX1]",N#CC1=**=*NC1=S +1069,Cyano_pyridone_B,"[#6]1(=,:[#6](-,:[#6](=O)-,:[#7]-,:[#6](=,:[#7]1)[!#1!#6])C#[#7])[#6]",*C1=NC(C)=C(C#N)C(=O)N1 +1070,Cyano_imine_A,[N!H0]N=C(C#[NX1])C=[!#6&!R],*=CC(C#N)=NN +1071,Cyano_imine_B,C(C#[NX1])(C#[NX1])=N[N!H0]c1ccccc1,N#CC(C#N)=NNc1ccccc1 +1072,Cyano_cyano_A,"C(C#[NX1])(C#[NX1])C([$(C#[NX1]),$(C=N)])C#[NX1]",*C(C#N)C(C#N)C#N +1073,Anil_alk_ene,c1ccc4c(c1)NCC9C4C=CC9,C1C=CC2C1CNc1ccccc12 +1074,Anil_no_alk,"c1([NH2])[cH][cH]c([#7,#8,CH2,CH3])[cH][cH]1",*c1[cH][cH]c([NH2])[cH][cH]1 +1075,Anil_di_alk_furan_A,"N([CH2,CH3])([CH2,CH3])c1oc(C=N[N!H0]C(=[!#1!#6]))[cH][cH]1",*N(*)c1[cH][cH]c(C=NNC=*)o1 +1076,Amino_acridine_A,c1cccc5c1c(c8c(n5)cccc8)[#7],Nc1c2ccccc2nc2ccccc12 +1077,Thiaz_ene_A,"C1([CH2,CH3,$(cc)])=C([H,CH2,CH3,$(C=O)])SC(N1([H,$([C!H0]),$(cc)]))=[#7!R]",*C1=C(*)N(*)C(=N)S1 +1078,Thiaz_ene_B,"C1([$(NC(=[OX1])cc),NH2])=C(-!@C(=[OX1])N[CH2,CH3])SC(N1[$([CH2][CH]=[CH2]),$(cc)])=[SX1]",*NC(=O)C1=C(*)N(*)C(=S)S1 +1079,Thio_carbonate_A,"[#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]",*c1ccc2c(c1)SC(=*)O2 +1080,Thiophene_amino_Aa,[NH2]c1sc([!#1])c([!#1])c1C=[OX1],*c1sc([NH2])c(C=O)c1* +1081,Thiophene_amino_Ab,"[H,CH2,CH3,$(cc)]c1sc([#7!H0][#6](=O)[#6])c(C(=O)[#8])c1[$(c2ccccc2),$(c3sccc3)]",*c1sc(NC(C)=O)c(C(O)=O)c1* +1082,Thiophene_hydroxy,"[#16]1-,:[#6]=,:[#6]-,:[#6](=,:[#6]1)[OH1]",[OH]C1=CSC=C1 +1083,Sulfonamide_A,"c1(c(c([cH]c([cH]1)[F,Cl,Br,I])[F,Cl,Br,I])[OH1])S(=[OX1])(=[OX1])N",*c1[cH]c(*)c([OH])c(S(N)(=O)=O)[cH]1 +1084,Sulfonamide_B,c1c(ccc(c1)[NH]S(=[OX1])=[OX1])[OH1],O=S(=O)[NH]c1ccc([OH])cc1 +1085,Thio_ketone,"[#6]-,:[CX3](=[SX1])-,:[#6]",CC(C)=S +1086,Anthranil_one_A,"[$(c1c(c(ccc1)C(-cc)=[OX1])[NH&!$([NH][CX3]=[OX1])]),$(c1c(c(ccc1)C(-cc)=[OX1])[NH2])]",* +1087,Diazox_sulfon_A,"N(c1ccccc1)S(=[OX1])(=[OX1])c2c3n[o,s]nc3ccc2",O=S(=O)(Nc1ccccc1)c1cccc2n*nc12 +1088,Dyes3A,"[#7v4,#7+](-,:[#6]=,:[#6])=,:[#6]-[CH]=CN([CX4])[#6]",CN(C)C=CC=*C=C +1089,Dyes5A,"[CH2,CH3][#7](:,-[#6]:[#6])~[#6]-,:[#6]=,:[#6]-[#6]~[#6]:,-[#7]",*N(~CC=CC~C:N):C:C +1090,Rhod_sat_A,"[#7]1-,:[#6](=[#16])-,:[#16]-,:[#6X4]-,:[#6]1=[#8]",O=C1CSC(=S)N1 +1091,Imine_one_fives,[#6]1(=[!#1!#6!R])[#6](=[OX1])[!#1!#6]*=[#6]1,*=C1C=**C1=O +1092,Imine_one_sixes,C1(C(=[OX1])NC(=[OX1])NC1(=[OX1]))=N,N=C1C(=O)NC(=O)NC1=O +1093,Naphth_amino_A,"c1ccc4c5c(cccc15)[#7]=,:[#6]-,:[#7]4",C1=Nc2cccc3cccc(c23)N1 +1094,Naphth_amino_B,c1ccc4c5c(cccc15)[N!H0][CX4][N!H0]4,C1Nc2cccc3cccc(c23)N1 +1095,Thio_dibenzo,"[SX1]=[#6]1-,:[#6]=,:[#6]-,:[!#1!#6]-,:[#6]=,:[#6]1",S=C1C=C*C=C1 +1096,Het_65_A,"[OX1]=CC1=C2N=C([CH2,CH3])C=C([OH1])N2N=C1",*C1=NC2=C(C=O)C=NN2C([OH])=C1 +1097,Het_6_tetrazine,"N~c1[n,$(c(N))][n,c!H0,$(c[N!H0])]c([N!H0,$([OX2][CH2,CH3])])nn1",*c1*:*c(~N)nn1 +1098,Imidazole_A,"[#7]1-,:[#6](-c2ccccc2)=,:[#6](-c3ccccc3)-,:[#7!H0]-,:[#6]1-ca",*cC1NC(c2ccccc2)=C(c2ccccc2)N1 +1099,Anthranil_acid_A,c1(C(=[OX1])[OH1])c([N!H0]N=C)cccc1,C=NNc1ccccc1C(=O)[OH] +1100,Dhp_bis_amino_CN,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1101,Anisol_A,"c1(O[CH2,CH3])c([H,CH2,CH3])[cH]c(O[CH2,CH3])c([CH2][$([N!H0]C(=[OX1])[CH2][CH2][CH2,CH3]),$([C!H0]([CH2,CH3])[N!H0]C(=[SX1])[N!H0])])[cH]1",*[CH2]c1[cH]c(O*)c(*)[cH]c1O* +1102,Anisol_B,"[CH2,CH3](c4c([cH][cH]c([cH]4)[CH2][N!H0][CX4])O[CH2,CH3])",*Oc1[cH][cH]c([CH2]NC)[cH]c1* +1103,Anthranil_acid_B,"c3cc(C(=[OX1])[N!H0]c4ccccc4C(=[OX1])[OH1])cc1c3C(=[OX1])N([CH2,CH3])C1=[OX1]",*N1C(=O)c2ccc(C(=O)Nc3ccccc3C(=O)[OH])cc2C1=O +1104,Anthranil_acid_C,"[#6]1(=,:[#6]([NH2])-,:[#7](-c7ccccc7C(=[OX1])[OH1])-,:[#7]=,:[#6]1C=[OX1])[$(C#[NX1]),$(C=S)]",*C1=C([NH2])N(c2ccccc2C(=O)[OH])N=C1C=O +1105,Anthranil_acid_D,"c12ncccc1-,:[#6]([NH2])=,:[#6](C(=[OX1])~[OX1,O-])-,:[#16]2",*~C(=O)C1=C([NH2])c2cccnc2S1 +1106,Anthranil_acid_E,C1(=[OX1])C(=[CH][NH]c2c(C(=[OX1])[OH1])cccc2)N=C(c3ccccc3)O1,O=C1OC(c2ccccc2)=NC1=[CH][NH]c1ccccc1C(=O)[OH] +1107,Anthranil_acid_F,c1([OH1])ccc([N!H0]C(=[OX1])cc)c(c1)C(=[OX1])[OH1],ccC(=O)Nc1ccc([OH])cc1C(=O)[OH] +1108,Anthranil_acid_G,"c1([cH][cH]c(O[CH2,CH3])[cH]c1(C(=[OX1])[OH1]))[N!H0]cc",*Oc1[cH][cH]c(Ncc)c(C(=O)[OH])[cH]1 +1109,Anthranil_acid_H,"c1ccc4c(c1C(=[OX1])[OH1])[#7!H0]-,:[#6](=,:[#6]4cc)cc",ccC1=C(cc)c2cccc(C(=O)[OH])c2N1 +1110,Anthranil_acid_I,c1(oc([#6])[cH][cH]1)C(=[OX1])[N!H0]c1[cH][cH][cH][cH]c1(C(=[OX1])[OH1]),Cc1[cH][cH]c(C(=O)Nc2[cH][cH][cH][cH]c2C(=O)[OH])o1 +1111,Anthranil_acid_J,[N!H0](cc)c5c(C(=[OX1])[OH1])ccc(n5)-cc,ccNc1nc(-cc)ccc1C(=O)[OH] +1112,Anthranil_amide_A,c1ccccc1C(=[OX1])[N!H0]c2ccccc2C(=[OX1])[N!H0][N!H0]c3nccs3,O=C(Nc1ccccc1C(=O)NNc1nccs1)c1ccccc1 +1113,Azulene,c1ccc4c(cc1)ccc4,c1ccc2cccc2cc1 +1114,Anil_alk_A,"[CH2,CH3]Occ[CH2][N!H0]c1[cH]c2n[cH]n([#6!H0])c2[cH][cH]1",*Occ[CH2]Nc1[cH][cH]c2c([cH]1)n[cH]n2C +1115,Anil_alk_B,"[N!H0](c1[cH][cH]c([CH2,CH3])[cH][cH]1)[CH2][CH2]c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c([CH2][CH2]Nc2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1116,Anil_alk_C,"[N!H0](c1ccccc1)C([#6])([#6])c2[cH][cH]c(O[CH2,CH3])[cH][cH]2",*Oc1[cH][cH]c(C(C)(C)Nc2ccccc2)[cH][cH]1 +1117,Anil_alk_D,"[N!H0](c1[cH][cH]c([C!H0]([CH2,CH3])[CH2,CH3])[cH][cH]1)[CH2][CH2]N([CH2,CH3])[CH2,CH3]",*C(*)c1[cH][cH]c(N[CH2][CH2]N(*)*)[cH][cH]1 +1118,Anil_alk_thio,c1ccc2c(c1)C3=C(C([#6])([#6])N2)SSC3=*,*=C1SSC2=C1c1ccccc1NC2(C)C +1119,Anil_alk_indane,c1(ccc4c(C6Cc8c(C6N4)cccc8)c1)[CX4],Cc1ccc2c(c1)C1Cc3ccccc3C1N2 +1120,Anil_di_alk_F,"c1c(ccc(N([H,CX4])([H,CX4]))c1)[CX4]c2ccc(cc2)N([H,CX4])([H,CX4])",*N(*)c1ccc(Cc2ccc(N(*)*)cc2)cc1 +1121,Anil_di_alk_J,"[CH2,CH3][#7]([CH2,CH3])c1[cH][cH]c([#6!H0]=[#7][#7]=[#6]([#6])-cc)[cH][cH]1",*N(*)c1[cH][cH]c(C=NN=C(C)cc)[cH][cH]1 +1122,Anil_di_alk_I,"[cH]1c([N!H0]C(=[OX1])c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=O)c2ccccc2)[cH]1 +1123,Anil_di_alk_M,[cH]1c([cH]nc7c1[cH][cH][cH][cH]7)[CH2]N2c3c([CH2][CH2]2)[cH][cH][cH][cH]3,[cH]1[cH][cH]c2c([cH]1)[CH2][CH2]N2[CH2]c1[cH]nc2[cH][cH][cH][cH]c2[cH]1 +1124,Anil_di_alk_N,c12[cH][cH][cH][cH]c1[C!H0]=[C!H0]C3C(C#[NX1])[CH2][C!H0]N23,N#CC1[CH2]CN2C1C=Cc1[cH][cH][cH][cH]c12 +1125,Anil_di_alk_ene_B,"[CH2,CH3]N([CH2,CH3])C1=Cc2ccccc2[CH2]1",*N(*)C1=Cc2ccccc2[CH2]1 +1126,Anil_di_alk_furan_B,"[CH2,CH3]N([CH2,CH3])c1[cH][cH]c(o1)[C!H0]=CC#[NX1]",*N(*)c1[cH][cH]c(C=CC#N)o1 +1127,Anil_di_alk_indol,"c12[cH][cH]c(N([CH2,CH3])[CH2,CH3])[cH]c1-,:[#6](S(=[OX1])=[OX1])=,:[#6H]-,:[#7!H0]2",*N(*)c1[cH][cH]c2c([cH]1)C(S(=O)=O)=[CH]N2 +1128,Anil_no_alk_indol_A,"c12[cH][cH]c([NH2])[cH]c1[cH][cH]n2[CH2,CH3]",*n1[cH][cH]c2[cH]c([NH2])[cH][cH]c21 +1129,Anil_NH_alk_A,"c1([N!H0][CH2,CH3])[cH][cH]c2c([cH]1)[#7!H0]-,:[#6](=[OX1])-,:[#7!H0]2",*Nc1[cH][cH]c2c([cH]1)NC(=O)N2 +1130,Anil_NH_alk_B,[N!H0](c1ccacc1)c2ccc([N!H0][C!H0])cc2,CNc1ccc(Nc2cc*cc2)cc1 +1131,Anil_NH_alk_C,[C!H0][N!H0]c1[cH][cH][cH][cH]c1[N!H0][C!H0],CNc1[cH][cH][cH][cH]c1NC +1132,Anil_NH_alk_D,"[NH2]c1c([N!H0][C!H0]([#6])[C!H0][CH2,CH3])c[cH][cH][cH]1",*CC(C)Nc1c[cH][cH][cH]c1[NH2] +1133,Anil_NH_no_alk_A,n1[cH]c([NH2])[cH][cH]c1([N!H0]cc),ccNc1[cH][cH]c([NH2])[cH]n1 +1134,Anil_NH_no_alk_B,"[NH2]c1c([N!H0]S(=[OX1])=[OX1])[cH]c([N!H0][CH2,CH3])c([F,Cl,Br,I])[cH]1",*Nc1[cH]c(NS(=O)=O)c([NH2])[cH]c1* +1135,Anil_OH_alk_A,c1ccccc1[CH2][N!H0]c2[cH][cH]c([OH1])[cH][cH]2,[OH]c1[cH][cH]c(N[CH2]c2ccccc2)[cH][cH]1 +1136,Anil_OH_no_alk_A,[NH2]c1c([OH1])cc(S(=[OX1])(=[OX1])[OH1])cc1,[NH2]c1ccc(S(=O)(=O)[OH])cc1[OH] +1137,Anil_OH_no_alk_B,c1([NH2])c([OH1])c(C=[OX1])[cH]c2[cH][cH][cH][cH]c12,[NH2]c1c([OH])c(C=O)[cH]c2[cH][cH][cH][cH]c12 +1138,Anil_OC_alk_A,"[cH]1[cH][cH]c2c([cH]1)c3c(o2)[cH]c([N!H0][CH2,CH3])c(O[CH2,CH3])[cH]3",*Nc1[cH]c2oc3[cH][cH][cH][cH]c3c2[cH]c1O* +1139,Anil_OC_alk_B,"c2ccccc2N1C(=[OX1])C([N!H0]c2ccc(O[CH2,CH3])cc2)=C([F,Cl,Br,I])C1=[OX1]",*Oc1ccc(NC2=C(*)C(=O)N(c3ccccc3)C2=O)cc1 +1140,Anil_OC_alk_C,"[H,CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2]c2nccn2",*Oc1[cH][cH][cH][cH]c1N[CH2]c1nccn1 +1141,Anil_OC_alk_D,"[CH2,CH3]Oc1[cH][cH]c([CH2,CH3])[cH]c1[NH][CH2]c2c([CH2,CH3,$(O[CH2,CH3])])cccc2",*Oc1[cH][cH]c(*)[cH]c1[NH][CH2]c1ccccc1* +1142,Anil_OC_alk_E,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][CH2][C!H0]([OH1])[CH2,CH3]",*Oc1[cH][cH][cH][cH]c1N[CH2]C(*)[OH] +1143,Anil_OC_alk_F,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0][C!H0]([#16])C=[OX1]",*Oc1[cH][cH][cH][cH]c1NC(S)C=O +1144,Anil_OC_no_alk_B,c1ccc4c(c1Oc8[cH][cH]c([cH][cH]8)[N!H0])cccc4,Nc1[cH][cH]c(Oc2cccc3ccccc23)[cH][cH]1 +1145,Anil_OC_no_alk_C,[NH2]c1ncccc1O[CH2]cc,cc[CH2]Oc1cccnc1[NH2] +1146,Anil_no_alk_A,"[NH2]c1c(N=[#6]2-,:[#6!H0]=,:[#6]~[#6]~[#6]=,:[#6]2)[cH][cH][cH][cH]1",[NH2]c1[cH][cH][cH][cH]c1N=C1C=C~C~C=C1 +1147,Anil_no_alk_B,"[NH2]c1c(n2cccc2)[cH]c([CH2,CH3])c([CH2,CH3])[cH]1",*c1[cH]c([NH2])c(n2cccc2)[cH]c1* +1148,Anil_no_alk_D,"n1c([NH2])c([CH2,CH3])[cH]c([CH2,CH3])c1[NH2]",*c1[cH]c(*)c([NH2])nc1[NH2] +1149,Anil_no_alk_C,"[NH2]c1[cH][cH]c([cH][cH]1)-c2[cH]c(C=[OX1])c([CH2,CH3])o2",*c1oc(-c2[cH][cH]c([NH2])[cH][cH]2)[cH]c1C=O +1150,Amino_acridine_B,c1cccc5c1cc8c(n5)nc2c(c8[#7])cccc2,Nc1c2ccccc2nc2nc3ccccc3cc12 +1151,Hzone_anil,c1([cH][cH]c([NH2])[cH][cH]1)C=N[N!H0],NN=Cc1[cH][cH]c([NH2])[cH][cH]1 +1152,Hzone_anthran_Z,c1cccc5c1cc8c(c5C=N[N!H0]c2ccccc2)cccc8,C(=NNc1ccccc1)c1c2ccccc2cc2ccccc12 +1153,Hzone_acyl_misc_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C(=[OX1])[N!H0]N=C([H,CH2,CH3])c2cc(*-*-*c3occc3)ccc2",*C(=NNC(=O)c1[cH][cH]c(*)o1)c1cccc(***c2ccco2)c1 +1154,Hzone_acyl_misc_B,n1[cH][cH][cH][cH]c1C(=[OX1])[N!H0]N=[C!H0]c2c(O[CH2]C(=[OX1])[OH1])cccc2,O=C([OH])[CH2]Oc1ccccc1C=NNC(=O)c1[cH][cH][cH][cH]n1 +1155,Hzone_thiophene_A,"[cH]2[cH][cH][cH]c1c2c([C!H0]=N[N!H0]([$(c3nc[cH]s3),$(c[cH][cH]),$(cncncn),$(cnnnn)]))c([H,$([OH1]),CH2,CH3])[a!c]1",*NN=Cc1c(*)*c2[cH][cH][cH][cH]c12 +1156,Hzone_thiophene_B,"c1(s[cH][cH]c1[H,CH2,CH3])[C!H0]=N[N!H0]c2ccccc2",*c1[cH][cH]sc1C=NNc1ccccc1 +1157,Hzone_phenone,"C(c1[cH]cc([H,CX4])[cH][cH]1)(c2[cH][cH]c([H,Cl])[cH][cH]2)=[$(NO[CH2][CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(NO[CH2][CH2]N([CH2,CH3])[CH2,CH3]),$(N[N!H0]C(=[NH1])[NH2]),$([#6!H0][#7])]",*c1c[cH]c(C(=*)c2[cH][cH]c(*)[cH][cH]2)[cH][cH]1 +1158,Hzone_furan_A,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[N!H0]c2nccs2",*C(=NNc1nccs1)c1[cH][cH]c(*)o1 +1159,Hzone_furan_B,"c1(oc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])=N[NH]c2ccncc2",*C(=N[NH]c1ccncc1)c1[cH][cH]c(*)o1 +1160,Hzone_furan_C,c1ccccc1N(c2ccccc2)N=[C!H0]c3ac([cH][cH]3)-c4cc(C(=[OX1])[OH1])ccc4,O=C([OH])c1cccc(-c2*c(C=NN(c3ccccc3)c3ccccc3)[cH][cH]2)c1 +1161,Hzone_furan_E,[OH1]C(=[OX1])c1cc(ccc1)-cacC=N[N!H0]C(=[OX1])[CH2][#8],O[CH2]C(=O)NN=Cc*c-c1cccc(C(=O)[OH])c1 +1162,Hzone_naphth_A,"[cH]1[cH][cH]c2[cH][cH]c(C=N[N!H0][$(cc),$(C=[SX1])])[cH]c2c1",*NN=Cc1[cH][cH]c2[cH][cH][cH]cc2[cH]1 +1163,Hzone_acid_A,"[cH]1[cH]c(O[CH2,CH3])[cH]c2C(=N[N!H0]c4[cH][cH]c(C(=[OX1])[OH1])[cH][cH]4)c3[cH]c(O[CH2,CH3])[cH][cH]c3c12",*Oc1[cH][cH]c2c([cH]1)C(=NNc1[cH][cH]c(C(=O)[OH])[cH][cH]1)c1[cH]c(O*)[cH][cH]c12 +1164,Hzone_acid_D,[OH1]C(=[OX1])c1ccc(cc1)NN=[C!H0]c2ac([cH][cH]2)-c3ccccc3,O=C([OH])c1ccc(NN=Cc2*c(-c3ccccc3)[cH][cH]2)cc1 +1165,Het_5_A,N1(c2ccccc2)N=C(C=[OX1])[CX4]C1=[OX1],O=CC1=NN(c2ccccc2)C(=O)C1 +1166,Het_5_B,N1(c2ccccc2)N=C([N!H0]C=[OX1])[CH2]C1=[OX1],O=CNC1=NN(c2ccccc2)C(=O)[CH2]1 +1167,Het_5_C,"N1=C(c2ccccc2)[CH2]C([OH1])([CX4](F)(F)F)N1[$(cccccc),$(C(=S)cccccc)]",*N1N=C(c2ccccc2)[CH2]C1([OH])C(F)(F)F +1168,Het_5_D,"N1(c2ccccc2)N=C([CH2,CH3])[C!H0](S[#6])C1=[OX1]",*C1=NN(c2ccccc2)C(=O)C1SC +1169,Het_5_E,"N1(c2cccc3ccccc23)N=C([CH2,CH3])[CH2]C1=[OX1]",*C1=NN(c2cccc3ccccc23)C(=O)[CH2]1 +1170,Het_5_ene,"C1(=[OX1])C(=C([CH2,CH3])[N!H0][CH2][CH2][CH2,CH3])N=C(c2ccccc2)O1",*[CH2][CH2]NC(*)=C1N=C(c2ccccc2)OC1=O +1171,Het_5_inium,"[#7]1(c2ccccc2)[#6!H0]=[#7+,#7v4](c3ccccc3)[#6](=Nc4ccccc4)N1",C1=*(c2ccccc2)C(=Nc2ccccc2)NN1c1ccccc1 +1172,Het_5_pyrazole_OH,"n1(c2[cH][cH][cH][cH][cH]2)nc([CX4])c([H,C!H0])c1[OH1]",*c1c(C)nn(c2[cH][cH][cH][cH][cH]2)c1[OH] +1173,Het_6_imidate_A,"N=[#6]1-,:[#7!H0]-,:[#6]([N!H0])=,:[#6]([N!H0])-,:[#7]=,:[#7]1",NC1=C(N)N=NC(=N)N1 +1174,Het_6_imidate_B,[N!H0](c1[cH][cH][cH][cH]c1[OH1])C2N=NC(=[#7])OC([NH2])=2,N=C1N=NC(Nc2[cH][cH][cH][cH]c2[OH])=C([NH2])O1 +1175,Het_6_pyridone_OH,[OH1]c2nc([OH1])ccc2,[OH]c1cccc([OH])n1 +1176,Het_6_pyridone_NH2,[OH1]c2nc([NH2])acc2[CH2]C(=[OX1])[#8],[NH2]c1*cc([CH2]C(O)=O)c([OH])n1 +1177,Het_6_hydropyridone,C1([N!H0])=N[C!H0](cc)[CH2]C(=[OX1])[N!H0]1,ccC1[CH2]C(=O)NC(N)=N1 +1178,Het_55_A,cc-n1nc2[CH2][SX2][CH2]c2c1[N!H0]C(=[OX1])[C!H0]=[C!H0],cc-n1nc2c(c1NC(=O)C=C)[CH2]S[CH2]2 +1179,Het_55_B,c1cOC2[CH2]C(=[OX1])OC12,O=C1[CH2]C2OccC2O1 +1180,Het_65_B,a1a3a(aaa1)[N!H0]N(C3=O)[#6],CN1N*2:*:*:*:*:*:2C1=O +1181,Het_65_C,"C1=CC=CC2=NC([$(C([!#1])=[C!H0]cc),$(coc)])=C(Ncc)N12",*C1=C(Ncc)N2C=CC=CC2=N1 +1182,Het_65_E,S1C(=C(C4=C1[N!H0]C(C(=[C!H0]4)C(=[OX1])[OH1])=[OX1])[NH2])C(=[OX1])[N!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1183,Het_65_F,"[#16]1-,:[#6]2:[#6](-,:[#6]([CH2,CH3])=,:[#6]1[CH2,CH3])c(ncn2)NN=C[#6]3=,:[#6]-,:[#6]=,:[#6]-,:[#8]3",*C1=C(*)C2:C(ncnc2NN=CC2=CC=CO2)S1 +1184,Het_65_G,"[CH2]1C(=[OX1])[#7]2-,:[#7]=,:[#6]([NH2])-,:[#6]([NH2])=,:[#6]2N=C1[#6]",CC1=NC2=C([NH2])C([NH2])=NN2C(=O)[CH2]1 +1185,Het_65_H,"[#6]1(=,:[#6]2-,:[#7](-,:[#6](-,:[#6]=,:[#6]-,:[#7]2)=[OX1])-,:[#7]=,:[#6]1[#6]3-,:[#7]-,:[#6]=,:[#6]-,:[#6]=,:3)C#[NX1]",N#CC1=C2NC=CC(=O)N2N=C1C1=CC=CN1 +1186,Het_65_I,c1(C(~[#8])~[#8])ccn2c(c1)cc(-cc)c2C(=[OX1])-cc,ccC(=O)c1c(-cc)cc2cc(C(~O)~O)ccn12 +1187,Het_65_J,"o1c([#6](~[#8])~[#8])cc2[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c12",*Oc1[cH]c2cc(C(~O)~O)oc2[cH]c1O* +1188,Het_65_K,N1=NNN=C2C=CC=C12,C1=CC2=NNN=NC2=C1 +1189,Het_65_L,"c12[cH]sc(C=[OX1])c2-,:[#6](=[OX1])-,:[#7]-,:[#7]=,:[#6]1[NH2]",[NH2]C1=NNC(=O)c2c1[cH]sc2C=O +1190,Het_65_Da,N1=C([#6])C2=CC=CC2=C([#6])N1,CC1=NNC(C)=C2C=CC=C12 +1191,Het_65_Db,n1ccccc1C2=C(N[#6])N1C(=N2)C=CC=C1,CNC1=C(c2ccccn2)N=C2C=CC=CN21 +1192,Het_65_pyridone_A,"c1([CH2][CH2,CH3])c([CH2,CH3])c2C(=[!#1!#6X1])N([C!H0][$(C(=O)O),$(cc)])C([H,$(S(C)[CH2,CH3])])=Nc2[a&!c;X2]1",*CN1C(=*)c2c(*c([CH2]*)c2*)N=C1* +1193,Het_65_imidazole,"[#6]1(=,:[#7]c3[cH][cH][cH][cH]c3n1[#6])[N!H0]C(=[OX1])[N!H0]c2[cH]ccc[cH]2",Cn1c2[cH][cH][cH][cH]c2N=C1NC(=O)Nc1[cH]ccc[cH]1 +1194,Het_65_mannich,[cH]1[cH]c2O[CH2]Oc2c([cH]1)[CH2]N2[CH2][CH2]cc2,c1cN([CH2]c2[cH][cH][cH]c3c2O[CH2]O3)[CH2][CH2]1 +1195,Het_66_A,c1ccc7c(c1)nnc(n7)[CH2]C=[OX1],O=C[CH2]c1nnc2ccccc2n1 +1196,Het_66_B,"c1ccc4c(c1)nc(nc4)[N!H0]C2=NC(C=C[N!H0]2)([CH2,CH3])[CH2,CH3]",*C1(*)C=CNC(Nc2ncc3ccccc3n2)=N1 +1197,Het_66_C,c1ccc2nc([C!H0]=C([OH1])[#6])c([C!H0]=C([OH1])[#6])nc2a1,CC([OH])=Cc1nc2*cccc2nc1C=C(C)[OH] +1198,Het_66_D,c1ccc7c(c1)nc(c(n7)[CH2]C(=[OX1])cc)[CH2]C(=[OX1])cc,ccC(=O)[CH2]c1nc2ccccc2nc1[CH2]C(=O)cc +1199,Het_66_E,c1ccc4c(c1)nc(c(n4)c2ccccc2)c7c(cccc7)[OH1],[OH]c1ccccc1c1nc2ccccc2nc1c1ccccc1 +1200,Het_66_anisole,"[CH2,CH3]Oc1[cH][cH][cH][cH]c1[N!H0]c2c3c(O[CH2,CH3])ccc(O[CH2,CH3])c3ncc2",*Oc1[cH][cH][cH][cH]c1Nc1ccnc2c(O*)ccc(O*)c12 +1201,Het_76_A,s1[cH][cH][cH]c1C2[N!H0]N=C(c4ccncc4)c3c(cccc3)N=2,c1ccc2c(c1)N=C(c1[cH][cH][cH]s1)NN=C2c1ccncc1 +1202,Het_465_misc,c1c4CCc4cc2OCOc12,C1Oc2cc3c(cc2O1)CC3 +1203,Het_565_A,c1n([#6])c2c3ncnc3c([OH1])[cH]c2c1C=[OX1],Cn1cc(C=O)c2[cH]c([OH])c3ncnc3c21 +1204,Het_565_indole,"[#6!H0]1=,:[#6!H0]-,:[#7]([CH2,CH3])c7c1c9[#6!H0]=,:[#6!H0]-,:[#7](c9c(c7O[CH2,CH3])O[CH2,CH3])[CH2,CH3]",*Oc1c(O*)c2c(c3c1N(*)C=C3)C=CN2* +1205,Het_666_A,"[#7]1-,:c2c(-,:[#6](=N)c6ccccc16)cccc2",N=C1c2ccccc2Nc2ccccc21 +1206,Het_666_B,"c1cccc9c1Oc2c(N9[CH2][CH2,CH3])cccc2",*[CH2]N1c2ccccc2Oc2ccccc21 +1207,Het_666_C,"c13cc2ccccc2cc1-,:[#7]([CH2,CH3])-,:[#6](=[OX1])-,:[#6](-cc[N!H0][CH2,CH3])=,:[#7]3",*NccC1=Nc2cc3ccccc3cc2N(*)C1=O +1208,Het_6666_A,c1ccc4c(c1)nc8c(n4)ccc5c8cccc5,c1ccc2c(c1)ccc1nc3ccccc3nc12 +1209,Het_pyridiniums_B,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:*2=,:[#6]1-,:*=,:[#7+,#7v4](~cc)-,:*=,:[#6]2[H,*]",*C1=**(~cc)=*C2=*1C=CC=C2 +1210,Het_pyridiniums_C,"[#6]1~[#6]~[#6]~[#7+,#7v4]2~[#6](~[#7]1)~[#6]3~[#6]~[#6]~[#6]~[#7](-cc)~[#6]3~[#7]2",ccN1~C~C~C~C2C~1~N*1~C~C~CN~C~1~2 +1211,Het_thio_5_A,"[CH2,CH3][SX2]c1n(-!@[CH2,CH3])c(-c2ccccc2)[cH]n1",*Sc1n[cH]c(-c2ccccc2)n1* +1212,Het_thio_5_B,C1(C=[OX1])(cc)[SX2]C=N[NH]1,ccC1(C=O)[NH]N=CS1 +1213,Het_thio_5_C,"[SX1]=[#6]1-,:[#7!H0]-,:[#7]=,:[#6](c2[cH][cH]c(O[CH2,CH3])[cH][cH]2)-,:[#8]1",*Oc1[cH][cH]c(C2=NNC(=S)O2)[cH][cH]1 +1214,Het_thio_5_imine_A,[#7]=C1SC(=[#7])N=C1,N=C1C=NC(=N)S1 +1215,Het_thio_5_imine_B,"N1([CH2,CH3])C(=S)N(-cc)C(=N-cc)C1=N-cc",*N1C(=S)N(cc)C(=Ncc)C1=Ncc +1216,Het_thio_5_imine_C,S1C(=N[N!H0])SC(=N-cc)C1=N-cc,ccN=C1SC(=NN)SC1=Ncc +1217,Het_thio_6_ene,c1cN=CC(=CN[#6])S1,CNC=C1C=NccS1 +1218,Het_thio_6_furan,"[CH2,CH3][SX2]c1nc(-c2o[cH][cH][cH]2)c(-c3o[cH][cH][cH]3)nn1",*Sc1nnc(-c2[cH][cH][cH]o2)c(-c2[cH][cH][cH]o2)n1 +1219,Het_thio_65_A,"[#7]1=,:[#6]([SX2][CH2,CH3])-,:[#7]=,:[#7]-,:[#6]2=,:[#6]1-,:[#6]([CH2,CH3])=,:[#7]-,:[#7]2-c3cccccc3",*SC1=NC2=C(N=N1)N(c1cccccc1)N=C2* +1220,Het_thio_65_B,"[N!H0][#6]3=,:[#7]-,:[#6](=,:[#7]-,:[#6]7=,:[#7]-,:[#7]=,:[#6](-,:[#7]37)S[#6])[N!H0][#6]",CNC1=NC2=NN=C(SC)N2C(N)=N1 +1221,Het_thio_65_C,"n1c2ccccc2n([CH2,CH3])c1S[CH2]C(=[OX1])[N!H0]N=[C!H0][C!H0]=[C!H0]",*n1c(S[CH2]C(=O)NN=CC=C)nc2ccccc21 +1222,Het_thio_65_D,"c1(S[CH2]C(=[OX1])[NH]-cc)nc2[cH]c([F,Cl,Br,I])c[cH]c2[nH]1",*c1c[cH]c2[nH]c(S[CH2]C(=O)[NH]cc)nc2[cH]1 +1223,Het_thio_66_A,c1ccc2[CH2][CH2]N=C(c2c1)[SX2][CH2]C(=[OX1])c2ccccc2,O=C([CH2]SC1=N[CH2][CH2]c2ccccc21)c1ccccc1 +1224,Het_thio_66_one,"c1cccc2c1-,:[#16]-,:[#6](C=[OX1])=,:[#6]-,:[#7]2",O=CC1=CNc2ccccc2S1 +1225,Het_thio_67_A,"[CH2,CH3][SX2]c1nc2OC=Ncc-c2nn1",*Sc1nnc2c(n1)OC=Ncc-2 +1226,Het_thio_656a,n1nc(S[CH2]C=[OX1])nc2c1c3c(n2[CH2][CH]=[CH2])cccc3,C=[CH][CH2]n1c2ccccc2c2nnc(S[CH2]C=O)nc21 +1227,Het_thio_656b,CC(=[OX1])[CH2][SX2]c1nc2[nH]c3[cH][cH][cH][cH]c3c2nn1,CC(=O)[CH2]Sc1nnc2c(n1)[nH]c1[cH][cH][cH][cH]c12 +1228,Het_thio_656c,"[#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]2-,:[#7+,#7v4]=,:[#6]3-,:[#7](N=C(c5ccccc5)[CX4]S3)-,:[#6]12",*1=C2SCC(c3ccccc3)=NN2C2C=CC=CC12 +1229,Het_thio_665,"c1ccc7c(c1)NC3=C(S7)SC(=C3)[CH2,CH3]",*C1=CC2=C(S1)Sc1ccccc1N2 +1230,Het_thio_666_A,"[cH]1[cH][cH][cH]c5N([H,CH3,$([CH2][C!H0])])c7c(~[H,$([N!H0][CX4]),$(cc)])c(~[H,$(cc)])c([H,NH2,$([OX2][CX4])])[cH]c7Sc15",*~c1c(~*)c2c([cH]c1*)Sc1[cH][cH][cH][cH]c1N2* +1231,Het_thio_676_A,"c1ccc4c(c1)Sc8[cH][cH]c([cH]c8C(C4)N([H,CX4])([H,CX4]))[H,#8,#16X2,CX4,$(N([H,CX4])[H,CX4])]",*c1[cH][cH]c2c([cH]1)C(N(*)*)Cc1ccccc1S2 +1232,Het_thio_676_B,[CH2]1Sc2[cH][cH][cH][cH]c2C(Occ)c3[cH][cH][cH][cH]c13,ccOC1c2[cH][cH][cH][cH]c2[CH2]Sc2[cH][cH][cH][cH]c21 +1233,Het_thio_pyr_A,"n1c(S[C!H0])c(C#[NX1])c(c2ccc(O[Ch2,CH3])cc2)[cH]c1(cc)",*Oc1ccc(c2[cH]c(cc)nc(SC)c2C#N)cc1 +1234,Het_thio_N_5A,N=C1N=CNS1,N=C1N=CNS1 +1235,Het_thio_N_5B,"[#6]1~[#6](~[#7]~[#7]~[#6](~[CH2,CH3])~[CH2,CH3])~[#7]~[#16]~[#6]1",*~C(~*)~N~N~C1~CC~S~N~1 +1236,Het_thio_N_5D,"[#7]1=,:[#7]-,:[#16]-,:[#6]=,:[#6]1-[#6]2-,:[#8]-,:[#7]=,:[#6](-cc)-,:[#7]=,:2",ccC1=NOC(C2=CSN=N2)=N1 +1237,Het_thio_N_55,[C!H0]c1nn(c3ccccc3)s2[a!c]acc12,Cc1nn(c2ccccc2)s2*:*cc12 +1238,Het_thio_N_65A,c1cC2=C(SNC2=S)CN1,S=C1NSC2=C1ccNC2 +1239,Het_thio_urea_ene,[OX1]=CC1=NN(cc)C(=[C!H0]cc)S1,ccC=C1SC(C=O)=NN1cc +1240,Het_pyraz_misc,C(F)(F)C(=[OX1])[N!H0]c1[cH]n([CH2][CH2]O[CH2]-cc)n[cH]1,cc[CH2]O[CH2][CH2]n1[cH]c(NC(=O)C(F)F)[cH]n1 +1241,Styrene_A,C1Cc3ccccc3C(c5c1cccc5)=CC,CC=C1c2ccccc2CCc2ccccc21 +1242,Styrene_B,"c1ccc4c(c1)[SX2,CX4]c8ccc(cc8C4=CC)[H,Cl,CX4]",*c1ccc2c(c1)C(=CC)c1ccccc1*2 +1243,Styrene_C,"c1ccc4c(c1)C([#6]8=,:[#6](SC4)-,:[#16]-,:[#6]=,:[#6]8)=C",C=C1C2=C(SCc3ccccc31)SC=C2 +1244,Styrene_anil_A,c1ccc7c(c1)C(c2c7ccc(c2)[NH2])=[C!H0][#6],CC=C1c2ccccc2c2ccc([NH2])cc21 +1245,Styrene_imidazole_A,C(=[C!H0][CH2]n1[cH]n[cH][cH]1)(-cc)-cc,ccC(=C[CH2]n1[cH][cH]n[cH]1)cc +1246,Ene_cyano_B,[NH2]c1nc2C(C#[NX1])=CC(=C)c2cc1C#[NX1],C=C1C=C(C#N)c2nc([NH2])c(C#N)cc21 +1247,Ene_cyano_C,C=C(C#[NX1])C(=[NH])NN,C=C(C#N)C(=N)NN +1248,Ene_cyano_D,C(C#[NX1])(C#[NX1])=C(S)S,N#CC(C#N)=C(S)S +1249,Ene_cyano_E,[OX1]=C[C!H0]=C(C#[NX1])[#6],CC(=CC=O)C#N +1250,Ene_cyano_F,[OH1]C(=[OX1])c1c([OH1])[cH]c([cH][cH]1)-c2[cH][cH]c(o2)[C!H0]=C(C#[NX1])-c3nccn3,N#CC(=Cc1[cH][cH]c(-c2[cH][cH]c(C(=O)[OH])c([OH])[cH]2)o1)c1nccn1 +1251,Ene_cyano_G,"[#7]1([#6])-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]=C(C#[NX1])c2nccs2",CN1C=CC=C1C=C(C#N)c1nccs1 +1252,Ene_five_het_G,"C1(=[OX1])C(=[C!H0][$(c2ccccc2),$(c2ccc[a!c]2)])N=C(aaa)[#16,$(Naa)]1",*C=C1N=C(*:*:*)*C1=O +1253,Ene_five_het_H,N1=CC(C(N1)=S)=C,C=C1C=NNC1=S +1254,Ene_five_het_I,c1(ccco1)[C!H0]=!@C2C(=[OX1])c5c(cccc5)[!#1!#6]2,O=C1C(=Cc2ccco2)*c2ccccc21 +1255,Ene_five_het_J,"S=[#6]1-,:[#7!H0]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1C(=[OX1])OC2=[C!H0]",C=C1OC(=O)C2=C1C=CNC2=S +1256,Ene_five_het_K,"[#7]1([#6])-,:[#6H]=,:[#6H]-,:[#6H]=,:[#6]1([CH]=C2C(=[OX1])[!#6]C=,:*2)",CN1[CH]=[CH][CH]=C1[CH]=C1*=C*C1=O +1257,Ene_five_het_L,[OX1]=C1C(=!@[C!H0]c3ccnc3)c2c(cccc2)N1,O=C1Nc2ccccc2C1=Cc1ccnc1 +1258,Ene_five_het_M,"C1=,:C[O,S]C(=CC=[OX1])C1=[OX1]",O=CC=C1*C=CC1=O +1259,Ene_five_het_N,"C1(=[OX1])C(=[C!H0]c2cc([F,Cl,Br,I])ccc2O[CH2,CH3])N=C(S[CH2,CH3])S1",*Oc1ccc(*)cc1C=C1N=C(S*)SC1=O +1260,Ene_six_het_B,"c2ccccc2C(=[OX1])[C!H0]=[#6]1-,:[#6](=[OX1])-,:[#7H]-,:[#6](=[OX1])-,:[#6](=[CH]c3ccccc3)-,:[#7!H0]1",O=C1[NH]C(=O)C(=[CH]c2ccccc2)NC1=CC(=O)c1ccccc1 +1261,Ene_six_het_C,[OX1]=C1cc[CH2]NC1=[C!H0],C=C1N[CH2]ccC1=O +1262,Ene_six_het_D,[OX1]=C1NNC(aa)=NC1=[C!H0],*:*C1=NC(=C)C(=O)NN1 +1263,Ene_quin_methide,"aaC([H,$(C#[NX1])])=[#6]1-,:[#6]=,:[#6]-,:[#6](=[OX1,N!R])-,:[#6]=,:[#6]1",*C(*:*)=C1C=CC(=*)C=C1 +1264,Ene_rhod_C,"S1C(=Ncc)N([H,$([CH2][CH2]O),$(cc)])C(=[OX1])C1(=[C!H0][$(cccCl),$(c[a!c])])",*C=C1SC(=Ncc)N(*)C1=O +1265,Ene_rhod_D,"S1C(=!@N[H,$([N!H0](N)cc)])N([H,$(cnccs)])C(=[OX1])C1=[C!H0]cc[Cl,$(O[C!H0])]",*ccC=C1SC(=N*)N(*)C1=O +1266,Ene_rhod_E,S1C(=[OX1])NC(=[SX1])C1=[C!H0]cc,ccC=C1SC(=O)NC1=S +1267,Ene_rhod_F,"n1ccc([C!H0]=C2C(=[OX1])NC(=[!#1!#6])N2)c1[CH2,CH3]",*c1nccc1C=C1NC(=*)NC1=O +1268,Ene_rhod_G,[OH1][CX3](=[OX1])c1cccc(c1)cac[C!H0]=C2C(=[!#1!#6])NC(=[!#1!#6])[!#1!#6]2,*=C1*C(=Cc*cc2cccc(C(=O)[OH])c2)C(=*)N1 +1269,Ene_rhod_H,"N1=C([CH2,CH3])C(=[OX1])N=C2N1C(=[OX1])C(=[C!H0]cc)S2",*C1=NN2C(=O)C(=Ccc)SC2=NC1=O +1270,Ene_rhod_I,"N1([CH2,CH3])C(=S)[N!H0]C(=[C!H0]c2cc(Br)ccc2)C1(=O)",*N1C(=O)C(=Cc2cccc(Br)c2)NC1=S +1271,Ene_rhod_J,"[CH2,CH3]N1C(=[#16,#7])[!#6]C(=[#6]2-,:[#6H]=,:[#6H]cc-,:[#7]2[CH2,CH3])C1=[OX1]",*N1cc[CH]=[CH]C1=C1*C(=*)N(*)C1=O +1272,Ene_misc_A,C1([#8])OC([#6])([#8])C=C1,CC1(O)C=CC(O)O1 +1273,Ene_misc_B,cc[CH2][C!H0](C=[OX1])N1C(=[OX1])[C!H0]2[CH2]C=C[CH2][C!H0]2C1(=[OX1]),cc[CH2]C(C=O)N1C(=O)C2[CH2]C=C[CH2]C2C1=O +1274,Ene_misc_C,"c1ccc4c(c1)N(C(C=C4)([CH2,CH3])[CH2,CH3])C(=[OX1])[N!H0]c3ccc(c(c3)O[CH2,CH3])O[CH2,CH3]",*Oc1ccc(NC(=O)N2c3ccccc3C=CC2(*)*)cc1O* +1275,Ene_misc_D,"c12[cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH]c1C([#6])=C([#6])S[CH2]2",*Oc1[cH]c2c([cH]c1O*)C(C)=C(C)S[CH2]2 +1276,Ene_misc_E,"c1(O[CH2,CH3])c(O[CH2,CH3])[cH]c2C=C[C!H0]Sc2[cH]1",*Oc1[cH]c2c([cH]c1O*)SCC=C2 +1277,Dhp_amidine_A,[N!H0]1N=C([N!H0])SC(-cc)=C1-cc,ccC1=C(cc)SC(N)=NN1 +1278,Dhp_amino_CN_A,"[NH2]C1=C(C#[NX1])[C!H0](cc)C([CH2,CH3])=C(C=C)O1",*C1=C(C=C)OC([NH2])=C(C#N)C1cc +1279,Dhp_amino_CN_B,"[NX3H2,OX2H1]C1=C(C#[NX1])[C!H0](cc)c2c(n(C)nc2)O1",*C1=C(C#N)C(cc)c2cnn(C)c2O1 +1280,Dhp_amino_CN_C,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](cc)-,:[#6](C#[NX1])=,:[#6](cc)-,:[#8]1",ccC1C(C#N)=C([NH2])OC(cc)=C1C#N +1281,Dhp_amino_CN_D,[NH2]C1=C(C#[NX1])[C!H0](cc)c2c(ccs2)O1,ccC1C(C#N)=C([NH2])Oc2ccsc21 +1282,Dhp_amino_CN_E,"[CH2,CH3][SX2]C1=C(C#[NX1])[C!H0](cc)C(C#[NX1])C(=O)N1",*SC1=C(C#N)C(cc)C(C#N)C(=O)N1 +1283,Dhp_amino_CN_F,"[NH2][#6]1=,:[#6](C#[NX1])-,:[#6!H0](c2cccs2)-,:[#6](C(=[OX1])O[#6])=,:[#6]([CH2,CH3])-,:[#8]1",*C1=C(C(=O)OC)C(c2cccs2)C(C#N)=C([NH2])O1 +1284,Dhp_amino_CN_G,"[SX2]1C=C(C#[NX1])C([#6])(C=[OX1])C([$(C=[OX1]),$(C#[NX1])])=C1[NH2]",*C1=C([NH2])SC=C(C#N)C1(C)C=O +1285,Dhp_amino_CN_H,[NH2]C1=C(C#[NX1])[C!H0](-cc)S[CX4]S1,ccC1SCSC([NH2])=C1C#N +1286,Dhp_keto_A,"[#7]1([H,CX4])-,:[#6]=,:[#6](C(=[OX1])ccc)-,:[#6]([#6])-,:[#6]([$(C=[OX1]),$(C#[NX1])])=,:[#6]1[CH3]",*C1=C([CH3])N(*)C=C(C(=O)ccc)C1C +1287,Cyano_amino_het_A,c1(c(nc4c(c1C#[NX1])c(c(cc4)C#[NX1])[NH2])[NH2])C#[NX1],N#Cc1ccc2nc([NH2])c(C#N)c(C#N)c2c1[NH2] +1288,Cyano_amino_het_B,n1c([SX2]c3c([NH2])cccc3)c(C#[NX1])c(-c2ccccc2)c(C#[NX1])c1([NH2]),N#Cc1c([NH2])nc(Sc2ccccc2[NH2])c(C#N)c1-c1ccccc1 +1289,Сyano_keto_A,"[CH2,CH3][C!H0](C#[NX1])C(=[OX1])[#6]",*C(C#N)C(C)=O +1290,Cyano_cyano_B,C1(C#[NX1])(C#[NX1])[C!H0](C(=[OX1])C)[C!H0]1,CC(=O)C1CC1(C#N)C#N +1291,Cyano_ene_amine_B,C=CC(C#[NX1])(C#[NX1])C(C#[NX1])=C[NH2],C=CC(C#N)(C#N)C(=C[NH2])C#N +1292,Cyano_ene_amine_C,ccC(=[OX1])[N!H0]C(=[OX1])C(C#[NX1])=[C!H0][N!H0]cc,ccNC=C(C#N)C(=O)NC(=O)cc +1293,Cyano_imine_C,[OX1]=S(=[OX1])C(C#[NX1])=N[N!H0],NN=C(C#N)S(=O)=O +1294,Cyano_imine_D,[OX1]=C1C(C#[NX1])=NNCC1,N#CC1=NNCCC1=O +1295,Cyano_pyridone_C,"C1(C([CH2,CH3])=C(C#[NX1])C(~[#8])~[#7]~[#6]1(~[#8]))=[C!H0]cc",*C1=C(C#N)C(~O)~N~C(~O)C1=Ccc +1296,Cyano_pyridone_D,"[OX1]=[#6]1-,:[#6](=,:[#6]-,:[#6](-,:[#7]-,:[#7]1)C=[OX1])C#[NX1]",N#CC1=CC(C=O)NNC1=O +1297,Cyano_pyridone_E,"ac[#6]1=,:[#6!H0]-,:[#6](co)=,:[#6](C#[NX1])-,:[#6](=[OX1])-,:[#7!H0]1",*cC1=CC(co)=C(C#N)C(=O)N1 +1298,Cyano_pyridone_G,"N1(c2ccc(O[CH2,CH3])cc2)C(=[OX1])C(C#[NX1])=CC(n3cncc3)=N1",*Oc1ccc(N2N=C(n3ccnc3)C=C(C#N)C2=O)cc1 +1299,Cyano_misc_A,c1(c2ccccc2nnc1)C(cc)C#[NX1],ccC(C#N)c1cnnc2ccccc12 +1300,Thio_aldehyd_A,"[#1,#6][C!H0](=[SX1])",*C=S +1301,Thio_amide_A,"[#6!H0]1=,:[#6]-,:[#8]-,:[#6](=,:[#6!H0]1)C(=[SX1])N5[CH2][CH2]*[CH2][CH2]5",S=C(C1=CC=CO1)N1[CH2][CH2]*[CH2][CH2]1 +1302,Thio_amide_B,[CX4][N!H0]C(cc)=[C!H0]C(=S)[N!H0]c1ccccc1,CNC(=CC(=S)Nc1ccccc1)cc +1303,Thio_amide_C,[C!H0](c1ccccc1)(c2ccccc2)C(=S)[N!H0],NC(=S)C(c1ccccc1)c1ccccc1 +1304,Thio_amide_D,[C!H0]N([C!H0])[#6]:[#6][N!H0]C(=S)[C!H0],CC(=S)NC:CN(C)C +1305,Thio_amide_E,"c1cccnc1C(=S)[N!H0]c2ccccc2O[CH2,CH3]",*Oc1ccccc1NC(=S)c1ccccn1 +1306,Thio_amide_F,acC(=S)[N!H0][N!H0]ca,*cNNC(=S)c* +1307,Thio_ester_A,C1=C(SC(C=C1)=S)[#7],NC1=CC=CC(=S)S1 +1308,Thio_ester_B,"ccC(=[SX1])[SX2][C!H0][CH2,CH3,$(cc)]",*CSC(=S)cc +1309,Thio_ester_C,"[#7]1-,:[#6](=[OX1])=,:[#6!H0]-,:[#6]([#6])-,:[#16]-,:[#6]1(=S)",CC1C=C(=O)NC(=S)S1 +1310,Thio_ene_amine_A,"S=CC([CH2,CH3])=C([CH2,CH3])N([CH2,CH3])[CH2,CH3]",*C(C=S)=C(*)N(*)* +1311,Thio_est_cyano_A,C1=CN(C(c5ccccc15)(C#[NX1])C(=S)S)C=[OX1],N#CC1(C(S)=S)c2ccccc2C=CN1C=O +1312,Thio_imide_A,c2ccccc2N1C(=[OX1])C(Sc3ccccc3)=[C!H0]C1=[OX1],O=C1C=C(Sc2ccccc2)C(=O)N1c1ccccc1 +1313,Thio_pyridine_A,c1(nanc(c2o[cH][cH][cH]2)n1)S[CX4],CSc1n*nc(c2[cH][cH][cH]o2)n1 +1314,Thio_thiomorph_Z,"[OX1]=C(N3CCSCC3)c9c([cH][cH][cH][cH]9)S[CH2,CH3]",*Sc1[cH][cH][cH][cH]c1C(=O)N1CCSCC1 +1315,Thio_urea_A,"c1c([N!H0][CX3](=[SX1])[N!H0][CH2][CH2][CH2]N([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1316,Thio_urea_B,"c1c([#7!H0]C(=S)[#7!H0][CH2][CH2][#7]([CH2,CH3])c2ccccc2)cccc1",*N([CH2][CH2]NC(=S)Nc1ccccc1)c1ccccc1 +1317,Thio_urea_C,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]C(=[OX1])c2a[a!c]cc2,O=C(NNC(=S)Nc1ccccc1)c1*:*cc1 +1318,Thio_urea_D,c1(ccccc1)[N!H0]C(=[SX1])N[N!H0]c2ccccc2,S=C(NNc1ccccc1)Nc1ccccc1 +1319,Thio_urea_E,c1c([N!H0]C(=[S1])[N!H0][CH2]c2ncccc2)cccc1,S=C(N[CH2]c1ccccn1)Nc1ccccc1 +1320,Thio_urea_F,C1[N!H0][N!H0]C(=[SX1])N[N!H0]1,S=C1NNCNN1 +1321,Thio_urea_G,"c1ccccc1[N!H0]C(=[SX1])N[N!H0][#6](=,:[#7R])-,:[#7R]",NC(=N)NNC(=S)Nc1ccccc1 +1322,Thio_urea_H,"[#6]1(=S)-,:[#7]([CH2]c2occc2)-,:[#6](cc)=,:[#7]-,:[#7!H0]1",ccC1=NNC(=S)N1[CH2]c1ccco1 +1323,Thio_urea_I,c1ccccc1[N!H0]C(=[SX1])[N!H0]N=Cc2ccnc2,S=C(NN=Cc1ccnc1)Nc1ccccc1 +1324,Thio_urea_J,c1(ccoc1[C!H0])C=N[N!H0]C(=[SX1])[N!H0],Cc1occc1C=NNC(N)=S +1325,Thio_urea_K,"[#6]1(=[SX1])-,:[#7]2-,:[#6]=,:[#6]-,:[#7]=,:[#7]-,:[#6]2=,:[#7][#7!H0]1",S=C1NN=C2N=NC=CN12 +1326,Thio_urea_L,[CX4][SX2]C(=N-aaaa)[N!H0]N=[#6],*:*:*:*N=C(NN=C)SC +1327,Thio_urea_M,"cc[#7]([CH2,CH3])[CH2][CH2][CH2][#7!H0]C(=S)[#7!H0]c1c([F,Cl,Br,I])[cH]c([CH2,CH3])[cH][cH]1",*c1[cH][cH]c(NC(=S)N[CH2][CH2][CH2]N(*)cc)c(*)[cH]1 +1328,Thio_urea_N,o1[cH][cH][cH]c1[CH2][N!H0]C(=S)N([C!H0])[CH2]c2ccccc2,CN([CH2]c1ccccc1)C(=S)N[CH2]c1[cH][cH][cH]o1 +1329,Thio_urea_O,[cH]1c([N!H0]C(=S)[N!H0][C!H0]c3oc([C!H0])[cH][cH]3)[cH]c2c(O[CH2]O2)[cH]1,Cc1[cH][cH]c(CNC(=S)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)o1 +1330,Thio_urea_P,"[OX1]=C-!@n1ccc2c1-,:[#7!H0]-,:[#6](=S)-,:[#7!H0]2",O=Cn1ccc2c1NC(=S)N2 +1331,Thio_urea_Q,"[cH]1[cH][cH][cH]c2[cH][cH][cH]c(c12)C([CH2,CH3])=N[N!H0]C(=S)[N!H0]ccc",*C(=NNC(=S)Nccc)c1[cH][cH][cH]c2[cH][cH][cH][cH]c12 +1332,Thio_urea_R,c1ccccc1[N!H0]C(=S)N[N!H0][C!H0]=[C!H0]C=[OX1],O=CC=CNNC(=S)Nc1ccccc1 +1333,Thio_carbam_A,"[CH2,CH3]SC(=S)[N!H0][CH2]-cc",*SC(=S)N[CH2]cc +1334,Thio_carbam_ene,S1C(=S)NC=C[CX4]1,S=C1NC=CCS1 +1335,Thio_carbonate_B,"[OX1]=[#6]1-,:[#16]c2cccc(O[CH2,CH3])c2-,:[#8]1",*Oc1cccc2c1OC(=O)S2 +1336,Thio_cyano_A,[N!H0]1C(=S)[C!H0](C#[NX1])[C!H0](-cc)[C!H0]=C1(-cc),ccC1C=C(cc)NC(=S)C1C#N +1337,Thio_imine_ium,"[CX4][#7+,#7v4]([CX4][OH1])=CS[C!H0]",CSC=*(C)C[OH] +1338,Thio_keto_het,"[#6]1=,:[#6](C=S)-,:[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]2=,:[#6]1",S=CC1=CC=C2C=CC=CN12 +1339,Thiophene_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=CC(=[OX1])c1c([SX2])sc([$(C#[NX1]),$(C=[OX1])])c1",*c1cc(C(=O)C=CN(*)*)c(S)s1 +1340,Thiophene_D,"s1[cH][cH]c(O[CH2,CH3])c1C(=[OX1])[N!H0][N!H0]",*Oc1[cH][cH]sc1C(=O)NN +1341,Thiophene_E,"c1(sc([H,CH2,CH3])[cH][cH]1)C([H,CH2,CH3])C(=[OX1])[NH]c2nccs2",*C(C(=O)[NH]c1nccs1)c1[cH][cH]c(*)s1 +1342,Thiophene_F,S(=[OX1])(=[OX1])[N!H0]c1sc([C!H0])c([C!H0])c1(C(=[OX1])[N!H0]),Cc1sc(NS(=O)=O)c(C(N)=O)c1C +1343,Thiophene_amino_B,"c2ccccc2[#7!H0]c1sc([$([#6]=[#8]),$(C#[#7]),$([#6]([#8!H0])=[#6])])c([#7])c1[$(C#[#7]),$([#6](n)n)]",*c1sc(Nc2ccccc2)c(*)c1N +1344,Thiophene_amino_C,"[C!H0][CH2]c1sc([N!H0]C(=[OX1])CCC=[OX1])c([$(C(=[OX1])O),$(C#[NX1])])c1[CH2,CH3]",*c1c([CH2]C)sc(NC(=O)CCC=O)c1* +1345,Thiophene_amino_D,C=CC(=[OX1])Nc1sc(C(=[OX1])O)c([C!H0])c1(C#[NX1]),Cc1c(C(O)=O)sc(NC(=O)C=C)c1C#N +1346,Thiophene_amino_E,"[#6]1=,:[#6]-,:[#16]-,:[#6](=,:[#6]1[NH2])[C!H0]=[C!H0][#6]2=,:[#6]-,:[#6]=,:[#6]-,:[#16]2",[NH2]C1=C(C=CC2=CC=CS2)SC=C1 +1347,Thiophene_amino_F,[NH2]c1sc([NH]C(=[OX1])c3ccccc3)c(C#[NX1])c1c2aaaaa2,N#Cc1c([NH]C(=O)c2ccccc2)sc([NH2])c1c1*:*:*:*:*1 +1348,Thiophene_amino_G,cccccc-c1sc([N!H0]C(=[OX1])[#6])c(C(=[OX1])[OH1])c1,CC(=O)Nc1sc(-cccccc)cc1C(=O)[OH] +1349,Thiophene_amino_H,[#6!H0][N!H0]c1sc([#6!H0])c([#6!H0])c1C(=[OX1])[N!H0]cc,CNc1sc(C)c(C)c1C(=O)Ncc +1350,Keto_naphthol_A,"[#6]C(=[OX1])c1cccc2cccc([OH1,NH2])c12",*c1cccc2cccc(C(C)=O)c12 +1351,Keto_thiophene,"c1(sc2ccccc2c1([CH2,CH3]))C(=[OX1])[CH2][CH2,CH3]",*[CH2]C(=O)c1sc2ccccc2c1* +1352,Keto_phenone_A,c1cccc5c1C(c8c5nacc8)=[OX1],O=C1c2ccccc2c2n*ccc21 +1353,Keto_phenone_B,c1cccc5c1C(C8C5=N[!#1!#6]=CC8)=[OX1],O=C1C2CC=*N=C2c2ccccc21 +1354,Keto_phenone_C,c1(cc3c(c5ccccc15)c4c(C3=[OX1])cccc4)[OH1],O=C1c2ccccc2c2c1cc([OH])c1ccccc12 +1355,Keto_phenone_zone_A,c1c(cccc1)C(=[OX1])[N!H0]N=C2c3c(cccc3)c4c2cccc4,O=C(NN=C1c2ccccc2c2ccccc21)c1ccccc1 +1356,Keto_keto_beta_B,[CX4]1C(=[OX1])NNC(=[OX1])1,O=C1CC(=O)NN1 +1357,Keto_keto_beta_C,c1ccc7c(c1)C(C(=C7[#8!H0])[#6])=[OX1],CC1=C(O)c2ccccc2C1=O +1358,Keto_keto_beta_D,[OX1]=CC=[C!H0][OH1],O=CC=C[OH] +1359,Keto_keto_beta_E,[OX1]=C[C!H0]=C([OH1])C([OH1])=[C!H0]C(=[OX1])[#6],CC(=O)C=C([OH])C([OH])=CC=O +1360,Keto_keto_beta_F,"[CH2,CH3]C([OH1])=C(C(=[OX1])[CH2,CH3])[C!H0]C#C",*C(=O)C(CC#C)=C(*)[OH] +1361,Keto_keto_gamma,[OX1]=C2[CX4]CC(=[OX1])c7c2cccc7,O=C1CCC(=O)c2ccccc21 +1362,Thiaz_ene_C,"[#6]1([F,Cl,Br,I,$([#7v4R,#7v4R+](=,:[#6R])-,:[#6R])])=,:[#6](-!@C=N)-,:[#16]-,:[#6](=[OX1])-,:[#7]1",*C1=C(C=N)SC(=O)N1 +1363,Acyl_het_A,"[#7v4,#7+](=,:*-,:*=,:*)-,:*=O",*=**=**=O +1364,Anil_di_alk_G,"[CX4]N([CX4])c1[cH][cH]c([#6]2=,:[#7]-,:[#6]=,:[#6]-,:*2)[cH][cH]1",CN(C)c1[cH][cH]c(C2=NC=C*2)[cH][cH]1 +1365,Anil_di_alk_H,"[cH]1c([N!H0]S(=[OX1])(=[OX1])c2caccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NS(=O)(=O)c2c*ccc2)[cH]1 +1366,Anil_di_alk_K,c1([NH2])ccc(N([CX3])[CX3])cc1,CN(C)c1ccc([NH2])cc1 +1367,Anil_di_alk_L,c1cc3c(cc1)N([CH2][CH2]N4C(c6c(C4=[OX1])cccc6)=[OX1])[CH2][CH2]3,O=C1c2ccccc2C(=O)N1[CH2][CH2]N1[CH2][CH2]c2ccccc21 +1368,Anil_di_alk_O,"[cH]1c([N!H0]C(=S)[N!H0]c2ccccc2)[cH]c(N([CH2,CH3])[CH2,CH3])[cH][cH]1",*N(*)c1[cH][cH][cH]c(NC(=S)Nc2ccccc2)[cH]1 +1369,Anil_di_alk_P,"[CH2,CH3]N([CH2,CH3])c1cc2nc(S[CH2,CH3])sc2cc1",*Sc1nc2cc(N(*)*)ccc2s1 +1370,Anil_di_alk_ene_A,"[CH2,CH3]N([CH2,CH3])C1=[C!H0]c2ccccc2[SX2]c3ccccc13",*N(*)C1=Cc2ccccc2Sc2ccccc21 +1371,Anil_di_alk_dhp,"N1C=C(C=[OX1])C(-c3ccc(N([CH2,CH3])[CH2,CH3])cc3)C2=C1(~[#7]~[#6](~[#16])~[#7]~[#6]2~[#7])",*N(*)c1ccc(C2C(C=O)=CNC3=C2C(~N)~N~C(~S)~N~3)cc1 +1372,Anil_alk_bim,[cH]1[cH]c([N!H0][CH2]c2ccccc2)[cH]c2c1n([#6])[cH]n2,Cn1[cH]nc2[cH]c(N[CH2]c3ccccc3)[cH][cH]c21 +1373,Anil_di_alk_coum,"c2ccccc2N([C!H0])[C!H0][C!H0][C!H0][N!H0]C(=[OX1])[#6]1-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6](=[OX1])-,:[#8]-,:[#6]([CH2,CH3])=,:1",*C1=CC(=O)OC(*)=C1C(=O)NCCCN(C)c1ccccc1 +1374,Anil_OC_no_alk_A,[NH2]c4[cH]nc(Oc5ccccc5)[cH][cH]4,[NH2]c1[cH][cH]c(Oc2ccccc2)n[cH]1 +1375,Ene_one_B,C([#16])([#7])=[C!H0]C=[C!H0]C=[OX1],NC(S)=CC=CC=O +1376,Ene_one_C,C1(=[OX1])C(C(C#[NX1])=[C!H0][#7])C([#7])C=C1,NC=C(C#N)C1C(N)C=CC1=O +1377,Ene_one_amide_A,"c1ccccc1[C!H0]NC(=[OX1])C([N!H0][CH2,CH3])=[C!H0]C(=[OX1])c2ccc(O[CH2,CH3])cc2",*NC(=CC(=O)c1ccc(O*)cc1)C(=O)NCc1ccccc1 +1378,Ene_one_amide_B,"c13ccc2ccccc2c1[C!H0][CX4]NC3=[C!H0]C(=[OX1])N([CH2,CH3])[CH2,CH3]",*N(*)C(=O)C=C1NCCc2c1ccc1ccccc21 +1379,Ene_one_one_A,[OX1]=CC1=C(SC(=[#6!H0][#6])S1)C=[OX1],CC=C1SC(C=O)=C(C=O)S1 +1380,Ene_one_one_B,C1(C(=[OX1])[CH2]C[CH2]C1(=[OX1]))=C([N!H0])C=[OX1],NC(C=O)=C1C(=O)[CH2]C[CH2]C1=O +1381,Ene_one_yne_A,C#CC(=[OX1])C#C,C#CC(=O)C#C +1382,Imine_one_B,"[N!H0](c1ccccc1)N=C(C(=[OX1])[CH2,CH3])[N!H0][$([N!H0]),$(cc)]",*NC(=NNc1ccccc1)C(*)=O +1383,Imine_ene_one_A,C1(C=Nc4c(N1)cccc4)=[C!H0]C=[OX1],O=CC=C1C=Nc2ccccc2N1 +1384,Imine_ene_one_B,c1cC(=[OX1])C=C1N=[C!H0]N([CX4])[CX4],CN(C)C=NC1=CC(=O)cc1 +1385,Imine_imine_A,c1ccc4c(c1)[#6]([#6]=[#7]4)=[#7!R],N=C1C=Nc2ccccc21 +1386,Imine_imine_B,cc[C!H0]=[C!H0][C!H0]=NN=C,ccC=CC=NN=C +1387,Imine_imine_C,"[CH2,CH3]N([CH2,CH3])[C!H0]=NC([CH2,CH3])=NN([CH2,CH3])cc",*C(N=CN(*)*)=NN(*)cc +1388,Imine_one_fives_B,[N!R]=C2C(=[OX1])c5c(cccc5)S2,N=C1Sc2ccccc2C1=O +1389,Imine_one_fives_C,cc[N!R]=C2C(=[!#1!#6])c5ccccc5N2,*=C1C(=Ncc)Nc2ccccc21 +1390,Imine_one_fives_D,C1(=[!#1!#6])C(N=CS1)=O,*=C1SC=NC1=O +1391,Imine_phenol_A,[#6]=[N!R]c3c([OH1])cccc3,C=Nc1ccccc1[OH] +1392,Imine_naphthol_A,"c12c([cH][cH][cH][cH]1)c(c([cH][cH]2)C(=N-cc)[CH2,CH3])[OH1]",*C(=Ncc)c1[cH][cH]c2[cH][cH][cH][cH]c2c1[OH] +1393,Pyrrole_C,"[#7]1([CX4])-,:[#6]([CH2,CH3])=,:[#6!H0]-,:[#6!H0]=,:[#6]1cc",*C1=CC=C(cc)N1C +1394,Pyrrole_D,"[#7]1(C)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CH2][N!H0]C(=[SX1])[N!H0]",CN1C=CC=C1[CH2]NC(N)=S +1395,Pyrrole_E,"[#7]1(c2[cH]a[a!c]a2)-,:[#6]([CX4])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[CX4]",CC1=CC=C(C)N1c1*:*:*[cH]1 +1396,Pyrrole_F,[cH]1[cH]n(-c2[a!c]ccc2C#[NX1])c[cH]1,N#Cc1cc*c1-n1c[cH][cH][cH]1 +1397,Pyrrole_G,"n1(c2c[cH]c([$([NH2]),$(cn)])c[cH]2)[cH][cH][cH][cH]1",*c1c[cH]c(n2[cH][cH][cH][cH]2)c[cH]1 +1398,Pyrrole_H,"C1=[Nv4,N+]([#6])CC[#7]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]12",C*1=CC2=CC=CN2CC1 +1399,Pyrrole_I,"[#7]1([CH2,CH3])-,:[#6]2=,:[#6](-,:[#6]:[#6]-,:[#6]2=[OX1])-,:[#6]=,:[#6]1[CH2,CH3]",*C1=CC2=C(C(=O)C:C2)N1* +1400,Pyrrole_J,"[#6]1(=,:[#6]2-,:[#6](=,:[#6](-,:[#7]1C(O)=[OX1])[CH2,CH3])S[CH2]S2)[CH2,CH3]",*C1=C2S[CH2]SC2=C(*)N1C(O)=O +1401,Pyrrole_K,"[#6]1(-,:[#7!H0]-,:[#6](c2[cH][cH][cH][cH][cH]2)=,:[#6]([CH2,CH3])-,:[#6H]=,:1)C(=[OX1])[OH1]",*C1=C(c2[cH][cH][cH][cH][cH]2)NC(C(=O)[OH])=[CH]1 +1402,Pyrrole_L,"[n!H0]1c(C(=[OX1])O[CH2,CH3])c([CH2,CH3])c([CH2][CH2,CH3])c1[CH2][CH2,CH3]",*[CH2]c1nc(C(=O)O*)c(*)c1[CH2]* +1403,Pyrrole_M,"[#7]1(c2ccccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6]1C=N[OH1]",[OH]N=CC1=CC=CN1c1ccccc1 +1404,Pyrrole_N,"[#7]1([C!H0]c2[cH][cH]c[cH][cH]2)-,:[#6]([C!H0])=,:[#6!H0]-,:[#6!H0]=,:[#6]1[C!H0]",CC1=CC=C(C)N1Cc1[cH][cH]c[cH][cH]1 +1405,Pyrrole_O,"[#7]1([CH2,CH3])-,:[#6]([CH2,CH3])=,:[#6](C(=[OX1])[#6])-,:[#6]=,:[#6]1-cc",*C1=C(C(C)=O)C=C(cc)N1* +1406,Thiaz_ene_D,"c2ccccc2[#7][#6]1=,:[#7+,#7v4]-,:[#6](c3ccccc3)=,:[#6][#16]1",*1=C(Nc2ccccc2)SC=C1c1ccccc1 +1407,Thiaz_ene_E,"C1(S[#6R])=C([C!H0]([#6])[#6])SC(N1([H,CH2,CH3]))=[OX1]",*N1C(=O)SC(C(C)C)=C1SC +1408,Quinone_B,"c1ccc4c(c1)[#6]7=,:[#6]8-,:[#6]([#6]4=[OX1])=,:[#6]-,:[#6]=,:[#6]-,:[#6]8=,:[#7]-,:[#8]7",O=C1C2=CC=CC3=NOC(=C23)c2ccccc21 +1409,Quinone_C,[OX1]=C1c2ccccc2C3=C([OH1])C(=[OX1])Nc4cccc1c34,O=C1Nc2cccc3c2C(=C1[OH])c1ccccc1C3=O +1410,Quinone_D,"[!#1!#6]=[#6]1[#6]=,:[#6][#6]=,:[#6][#6]1=[!#1!#6]",*=C1C=CC=CC1=* +1411,Diazox_A,O(c2ccccc2)c3cc1nonc1cc3,c1ccc(Oc2ccc3nonc3c2)cc1 +1412,Diazox_B,Clc2cc1nonc1cc2,Clc1ccc2nonc2c1 +1413,Diazox_C,N2=Nc1n[a!c]nc1N=Ncc2,*1nc2c(n1)N=NccN=N2 +1414,Diazox_D,[C!H0]1([OH1])c2n[a!c]nc2[C!H0]([OH1])C=C1,[OH]C1C=CC([OH])c2n*nc21 +1415,Diazox_E,[NH2]c1c([NH2])[cH][cH]c2nonc12,[NH2]c1[cH][cH]c2nonc2c1[NH2] +1416,Diazox_sulfon_B,c3ccccc3N1[C!H0][C!H0]N([C!H0][C!H0]1)S(=[OX1])(=[OX1])c4c2nsnc2ccc4,O=S(=O)(c1cccc2nsnc12)N1CCN(c2ccccc2)CC1 +1417,Sulfonamide_C,[cH]1c([N!H0]S(=[OX1])(=[OX1])c2ccc([!#1!#6])cc2)[cH]c3c(O[CH2]O3)[cH]1,*c1ccc(S(=O)(=O)Nc2[cH][cH]c3c([cH]2)O[CH2]O3)cc1 +1418,Sulfonamide_D,c1c(ccc(c1)[N!H0]S(=[OX1])(=[OX1]))[N!H0]S(=[OX1])(=[OX1]),O=S(=O)Nc1ccc(NS(=O)=O)cc1 +1419,Sulfonamide_E,cc[N!H0]S(=[OX1])(=[OX1])[N!H0]cc,ccNS(=O)(=O)Ncc +1420,Sulfonamide_F,"[OX1]=S(=[OX1])(cc)[N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NS(=O)(=O)cc)=N1 +1421,Sulfonamide_G,"[CH3]c5nc([N!H0]S(c2[cH][cH]c([cH][cH]2)O[CH2][CH2][CH2,CH3])(=[OX1])(=[OX1]))[cH][cH][cH]5",*[CH2][CH2]Oc1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]c([CH3])n2)[cH][cH]1 +1422,Sulfonamide_H,c1([cH][cH]c([NH2])[cH][cH]1)S(=[OX1])(=[OX1])[N!H0]c2[cH][cH][cH]nn2,[NH2]c1[cH][cH]c(S(=O)(=O)Nc2[cH][cH][cH]nn2)[cH][cH]1 +1423,Sulfonamide_I,"S(=[OX1])(=[OX1])(c1cn([CH2,CH3])cn1)[N!H0]c2cnn([CH2]ccO[CH2,CH3])c2",*Occ[CH2]n1cc(NS(=O)(=O)c2cn(*)cn2)cn1 +1424,Sulfonamide_J,"[#7]1(c2c([N!H0]S(=[OX1])(=[OX1])c3sccc3)cccc2)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",O=S(=O)(Nc1ccccc1N1C=CC=C1)c1cccs1 +1425,Imine_ene_A,cc[CH]=[CH][CH]=NN([CX4])[CX4],CN(C)N=[CH][CH]=[CH]cc +1426,Thiazol_SC_A,[#6][SX2]c1n[cH]cs1,CSc1n[cH]cs1 +1427,Thiazole_amine_A,[N!H0]c1nc(c2cnc([NH2])s2)cs1,Nc1nc(c2cnc([NH2])s2)cs1 +1428,Thiazole_amine_B,"c1(ccc([CH2,CH3])cc1)-c2nc([NH2])sc2[CH3]",*c1ccc(-c2nc([NH2])sc2[CH3])cc1 +1429,Thiazole_amine_C,"c1([N!H0][CH2]c2[cH][cH][cH]o2)nc(aaa([$(O[CH2,CH3]),CH2,CH3])aa)[cH]s1",**(:*:*):*:*c1[cH]sc(N[CH2]c2[cH][cH][cH]o2)n1 +1430,Thiazole_amine_D,"[#16]1-,:[#6]([N!H0]c2c([CH2,CH3,$(cc)])cccc2)=,:[#7+,#7v4]([CH2,CH3])-,:[#6]([#6])=,:[#6H]1",**1=C(Nc2ccccc2*)S[CH]=C1C +1431,Thiazole_amine_E,[OX1]=C[N!H0]c1c(-cc)nc([CH2]C#[NX1])s1,cc-c1nc([CH2]C#N)sc1NC=O +1432,Thiazole_amine_F,[#6!H0][#7!H0]c1nc(-C2=CN=C3N2C=CS3)cs1,CNc1nc(C2=CN=C3SC=CN23)cs1 +1433,Thiazole_amine_G,"[#6]1=,:[#6]-,:[#16]-,:[#6](NNS(=[OX1])=[OX1])=,:[#7]1",O=S(=O)NNC1=NC=CS1 +1434,Thiazole_amine_H,"c1ccc(C(=[OX1])[OH1])cc1[N!H0][#6]2=,:[#7]-,:[#6](=,:[#6!H0]-,:[#16]2)c3ccc([C!H0]([C!H0])[C!H0])cc3",CC(C)c1ccc(C2=CSC(Nc3cccc(C(=O)[OH])c3)=N2)cc1 +1435,Thiazole_amine_J,"[OX1]=S(=[OX1])(cc)[N!H0][N!H0][#6]1=,:[#7]-,:[#6](=,:[#6]-,:[#16]1)cc",ccC1=CSC(NNS(=O)(=O)cc)=N1 +1436,Thiazole_amine_K,"n1c2c(cc5c1-,:[#7]=,:[#6](-,:[#16]5)[#7])-,:[#16]-,:[#6](=,:[#7]2)[#7]",NC1=Nc2nc3c(cc2S1)SC(N)=N3 +1437,Thiazole_amine_L,s1ccc(-c2csc([NH2])n2)[cH]1,[NH2]c1nc(-c2ccs[cH]2)cs1 +1438,Thiazole_amine_M,"c1([N!H0]cc[CH2,CH3])nc(c2ccncc2)[cH]s1",*ccNc1nc(c2ccncc2)[cH]s1 +1439,Thiazole_amine_N,"[CH2,CH3]Oc1[cH][cH]c(O[CH2,CH3])[cH]c1[N!H0]c2scc(-c3ccc(O[CH2,CH3])cc3)n2",*Oc1ccc(-c2csc(Nc3[cH]c(O*)[cH][cH]c3O*)n2)cc1 +1440,Furan_acid_A,"c1(oc([CH2,CH3])c([CH2]Occ)[cH]1)[CX3](=[OX1])[OH1]",*c1oc(C(=O)[OH])[cH]c1[CH2]Occ +1441,Furan_A,"c1(oc([CH2,CH3])[cH][cH]1)[C!H0]([OH1])C#C[CX4]",*c1[cH][cH]c(C([OH])C#CC)o1 +1442,Colchicine_A,"[#6]1(-,:[#6](=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]1)[N!H0])=NC",CN=C1C=CC=CC=C1N +1443,Colchicine_B,"[CH2,CH3]Sc1ccc(cc1)C2=CC(=[OX1])[#6]3=,:[#6]-,:[#8]-,:[#6]=,:[#6]3C([OH1])=C2",*Sc1ccc(C2=CC(=O)C3=COC=C3C([OH])=C2)cc1 +1444,Colchicine_het,"c1cccc3-,:[#7]([CH2,CH3])-,:[#6](=NN=[#6]2-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]2)-,:[#16]-,:c13",*N1C(=NN=C2C=CC=CC=C2)Sc2ccccc21 +1445,Rhod_sat_B,"N1(c2c([CH2,CH3])cccc2)C(=S)N([CH2]aaaaa)[CH2]C1=[OX1]",*c1ccccc1N1C(=O)[CH2]N([CH2]*:*:*:*:*)C1=S +1446,Rhod_sat_C,N1(c2ccccc2)C(=NC=[OX1])S[CH2]C1=[OX1],O=CN=C1S[CH2]C(=O)N1c1ccccc1 +1447,Rhod_sat_D,N1(c2ccccc2)C(=[OX1])S[C!H0]([CH2]C(=[OX1])[N!H0]cc)C1=[OX1],ccNC(=O)[CH2]C1SC(=O)N(c2ccccc2)C1=O +1448,Rhod_sat_E,N1(c2ccccc2)C(=[OX1])S[C!H0]([N!H0]c3c4ccccc4ccc3)C1=[OX1],O=C1SC(Nc2cccc3ccccc23)C(=O)N1c1ccccc1 +1449,Rhod_sat_F,N1(c2ccccc2)C(=[OX1])S[CH2]C1=S,O=C1S[CH2]C(=S)N1c1ccccc1 +1450,Rhod_sat_imine_A,N1(C(=[OX1])c2ccccc2)C(=Nc3ccccc3)S[CH2]C1=[OX1],O=C1[CH2]SC(=Nc2ccccc2)N1C(=O)c1ccccc1 +1451,Melamine_A,"o1[cH][cH][cH]c1[CH2][N!H0]c1c2ccccc2nc([N!H0]c4c([H,CH2,CH3,SX2,$(O[C!H0])])cc([H,CH2,CH3,SX2,$(O[C!H0])])c([H,CH2,CH3,SX2,$(O[C!H0])])c4)n1",*c1cc(*)c(Nc2nc(N[CH2]c3[cH][cH][cH]o3)c3ccccc3n2)cc1* +1452,Melamine_B,"n1c(N([CH2,CH3])[CH2,CH3])nc(N([CH2,CH3])[CH2,CH3])nc1N([C!H0])C=[OX1]",*N(*)c1nc(N(*)*)nc(N(C)C=O)n1 +1453,Imidazole_B,"[CH2,CH3][CH2]S[CH2][#6]1=,:[#6]-,:[#7!H0]-,:[#6]=,:[#7]1",*[CH2]S[CH2]C1=CNC=N1 +1454,Imidazole_C,[C!H0]1(n2[cH]n[cH][cH]2)c3[cH]c(Br)[cH][cH]c3[CH2][CH2]c4[cH][cH][cH][cH]c14,Brc1[cH][cH]c2c([cH]1)C(n1[cH][cH]n[cH]1)c1[cH][cH][cH][cH]c1[CH2][CH2]2 +1455,Phthalimide_misc,[cH]1c(C(=[OX1])[OH1])[cH][cH]c2C(=[OX1])N(c3c[cH]c([#8])c[cH]3)C(=[OX1])c12,Oc1c[cH]c(N2C(=O)c3[cH][cH]c(C(=O)[OH])[cH]c3C2=O)c[cH]1 +1456,Hzide_naphth,[cH]1[cH][cH][cH]c9[cH]c([cH][cH]c19)[N!H0][N!H0]C=[OX1],O=CNNc1[cH][cH]c2[cH][cH][cH][cH]c2[cH]1 +1457,Naphth_amino_C,"c1ccc4c5c(cccc15)-,:[#6]=,:[#7]-,:[#7!H0]4",C1=NNc2cccc3cccc1c23 +1458,Naphth_amino_D,"c1ccc4c5c(cccc15)-,:[#7]=,:[#7]-,:[#7]4",c1cc2c3c(cccc3c1)N=NN2 +1459,Naphth_ene_one_A,"c1cc3c4c(c1)cccc4C(=CC3=[OX1])O[CH2,CH3]",*OC1=CC(=O)c2cccc3cccc1c23 +1460,Naphth_ene_one_B,[#7]c1ccc2c3c1cccc3C(=[OX1])C=C2C(F)(F)(F),Nc1ccc2c3c(cccc13)C(=O)C=C2C(F)(F)F +1461,Naphth_ene_one_C,c1(ccc4c5c(cccc15)C(C=C4)=[#7])[#7],Nc1ccc2c3c(cccc13)C(=N)C=C2 +1462,Coumarin_A,"c1(O[C!H0])[cH][cH]c2c3[cH][cH]c(O[CH2,CH3])[cH]c3-,:[#6](=[OX1])-,:[#8]c2c1",*Oc1[cH][cH]c2c([cH]1)C(=O)Oc1cc(OC)[cH][cH]c12 +1463,Coumarin_B,"c1([CH2][C!H0]=[CH2])cccc2-,:[#6!H0]=,:[#6](C(=[OX1])[N!H0]cc)-,:[#6](=[OX1])-,:[#8]c12",ccNC(=O)C1=Cc2cccc([CH2]C=C)c2OC1=O +1464,Coumarin_C,C1(C=Nc4c(O1)ccc(Cl)c4)=[OX1],O=C1C=Nc2cc(Cl)ccc2O1 +1465,Coumarin_D,c1c2C(c3ccccc3)=[C!H0]C(=[OX1])Oc2cc(O[CH2]coc)c1,coc[CH2]Oc1ccc2c(c1)OC(=O)C=C2c1ccccc1 +1466,Coumarin_E,"c1cc2c(o1)cc(Br)c3[#8]-,:[#6](=[OX1])-,:[#6]=,:[#6!H0]c23",O=C1C=Cc2c(c(Br)cc3occc23)O1 +1467,Coumarin_F,"c1ccc2c(c1)[#6]=,:[#6](C(=[OX1])[N!H0]c3c(Br)con3)-,:[#6](=[OX1])-,:[#8]2",O=C(Nc1nocc1Br)C1=Cc2ccccc2OC1=O +1468,Coumarin_G,"c1c([F,Cl,Br,I])cc2c(c1[F,Cl,Br,I])OC(=[N!H0])C(C(=[OX1])[NH2])=[C!H0]2",*c1cc(*)c2c(c1)C=C(C([NH2])=O)C(=N)O2 +1469,Coumarin_H,"c1cccc2[#6!H0]=,:[#6](C(=[OX1])[N!H0]c3scc(-cs[c!H0])n3)-,:[#6](=[OX1])-,:[#8]c12",csc-c1csc(NC(=O)C2=Cc3ccccc3OC2=O)n1 +1470,Cyanamide_A,[#8]C(=[OX1])[CH2][SX2]C(=NC#[NX1])[N!H0]c1ccccc1,N#CN=C(Nc1ccccc1)S[CH2]C(O)=O +1471,Steroid_A,[OX1]=C1CCC2C3C(=[OX1])CC4CCCC4C3CCC2=C1,O=C1CCC2C3C(CCC2=C1)C1CCCC1CC3=O +1472,Tert_butyl_A,[CH3]C([CH3])([CH3])c1[cH]c(C([CH3])([CH3])[CH3])c(O[C!H0][#7])c[cH]1,[CH3]C([CH3])([CH3])c1[cH]cc(OCN)c(C([CH3])([CH3])[CH3])[cH]1 +1473,Tert_butyl_B,[CH3]C([CH3])([CH3])c1c([OH1])c(C([CH3])([CH3])([CH3]))[cH]c([CH2]c2[cH][cH]c([OH1])cc2)[cH]1,[CH3]C([CH3])([CH3])c1[cH]c([CH2]c2ccc([OH])[cH][cH]2)[cH]c(C([CH3])([CH3])[CH3])c1[OH] +1474,Hydroquin_A,c1([OH1])ccc([OH1])c(c1)C(=!@C[#7])C=[OX1],NC=C(C=O)c1cc([OH])ccc1[OH] +1475,Tetrazole_A,"[CH2,CH3][#6]1=,:[#7]-,:[#7]=,:[#7]-,:[#7]1c2[cH][cH]c(O[CH3])[cH][cH]2",*C1=NN=NN1c1[cH][cH]c(O[CH3])[cH][cH]1 +1476,Misc_aminal_acid,"c1ccc4c(c1)COC(N4C(=[OX1])[CH2,CH3])(C(=[OX1])[OH1])[CH2,CH3]",*C(=O)N1c2ccccc2COC1(*)C(=O)[OH] +1477,Misc_aminoacid_A,[CX4]c1[cH][cH]c(C(=[OX1])[N!H0][C!H0]([CH2][CH2]S[CH3])C(=[OX1])[OH1])[cH][cH]1,Cc1[cH][cH]c(C(=O)NC([CH2][CH2]S[CH3])C(=O)[OH])[cH][cH]1 +1478,Misc_anilide_A,"c1([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH][cH]c([CH2,CH3])c([N!H0]C(=[OX1])[CH2][CH2]-cc)[cH]1",*c1[cH][cH]c(NC(=O)[CH2][CH2]cc)[cH]c1NC(=O)[CH2][CH2]cc +1479,Misc_anilide_B,"c1([N!H0]C(=[OX1])[N!H0][CH2][CH2][CH2,CH3])c([CH2,CH3])[cH]c(Br)[cH]c1[CH2,CH3]",*[CH2][CH2]NC(=O)Nc1c(*)[cH]c(Br)[cH]c1* +1480,Misc_anisole_A,"c1(c([cH]c5c([cH]1)c([cH]c([cH]5)c3[cH][cH]c(c([cH]3)O[CH2,CH3])O[CH2,CH3])[N!H0][CH3])O[CH2,CH3])O[CH2,CH3]",*Oc1[cH][cH]c(c2[cH]c(N[CH3])c3[cH]c(O*)c(O*)[cH]c3[cH]2)[cH]c1O* +1481,Misc_anisole_B,"c1([cH]c(O[CH2,CH3])c(O[CH2,CH3])[cH][cH]1)C(=[OX1])[CH2]N([CH2,CH3])c2ccc([CH2,CH3])cc2",*Oc1[cH][cH]c(C(=O)[CH2]N(*)c2ccc(*)cc2)[cH]c1O* +1482,Misc_anisole_C,[N!Ho](c1[cH][cH]c(O[CH3])c(O[C!H0])[cH]1)C(=[OX1])[N!H0][CH2][CH2][CH2]N([CH3])cc,COc1[cH]c(NC(=O)N[CH2][CH2][CH2]N([CH3])cc)[cH][cH]c1O[CH3] +1483,Misc_cyclopropane,C1([CH2][CH2]1)(C(=[OX1])[N!H0]c2ccc(O[CH2][#8])cc2)S(=[OX1])(=[OX1])-cc,ccS(=O)(=O)C1(C(=O)Nc2ccc(O[CH2]O)cc2)[CH2][CH2]1 +1484,Misc_furan_A,"c3c([CH2,CH3])c([CH2,CH3])oc3[CH2]N[CH2][C!H0](O[CH2,CH3])[CH2]Oc1ccc2c(O[CH2]O2)c1",*OC([CH2]N[CH2]c1cc(*)c(*)o1)[CH2]Oc1ccc2c(c1)O[CH2]O2 +1485,Misc_naphthimidazole,"c1c2c(cc5c1cccc5)-,:[#7!H0]-,:[#6](=,:[#7]2)COC(=[OX1])c8cc(cc(c8)[NH2])[NH2]",[NH2]c1cc([NH2])cc(C(=O)OCC2=Nc3cc4ccccc4cc3N2)c1 +1486,Misc_phthal_thio_N,"c1(c2ccccc2)nc(N([CH2,CH3])[CH2][CH2]NC(=[OX1])c3c(C(=[OX1])[OH1])cccc3)sn1",*N([CH2][CH2]NC(=O)c1ccccc1C(=O)[OH])c1nc(c2ccccc2)ns1 +1487,Misc_pyridine_OC,"[OX1]=C(c1[cH]c(O[CH3])nc(O[CH3])[cH]1)[N!H0][C!H0]([CH2,CH3])[CH2,CH3]",*C(*)NC(=O)c1[cH]c(O[CH3])nc(O[CH3])[cH]1 +1488,Misc_pyrrole_benz,"[#7]1(-c2[cH][cH][cH][cH]c2C(=[OX1])[N!H0][C!H0]([CH2,CH3])[CH2]O-cc)-,:[#6!H0]=,:[#6!H0]-,:[#6!H0]=,:[#6!H0]1",*C([CH2]Occ)NC(=O)c1[cH][cH][cH][cH]c1N1C=CC=C1 +1489,Misc_pyrrole_thiaz,"c1([C!H0]([CH2,CH3])[CH2][CH2]N[CH2]c2[n!H0]ccc2)nc(-c3ccccc3)[c!H0]s1",*C([CH2][CH2]N[CH2]c1cccn1)c1nc(-c2ccccc2)cs1 +1490,Misc_stilbene,C1(cc)=C(cc)[CH2][C!H0](C(=[OX1])[#6])[C!H0](C(=[OX1])[OH1])[CH2]1,CC(=O)C1[CH2]C(cc)=C(cc)[CH2]C1C(=O)[OH] +1491,Misc_trityl_A,C(cc)(cc)(cc)SccC(=[OX1])[OH1],ccC(cc)(cc)SccC(=O)[OH] +1492,Misc_urea_A,"c1(C([CX4])([CX4])[N!H0]C(=[OX1])N([CH2][CH2,CH3])[CH2][CH2][CH2][CH2]-cc)[cH][cH][cH]c(C(=[CH2])[CH2,CH3])[cH]1",*[CH2]N([CH2][CH2][CH2][CH2]cc)C(=O)NC(C)(C)c1[cH][cH][cH]c(C(*)=C)[cH]1 +1493,Imidazole_amino_A,n1c(c2ccccc2)c(c3ccccc3)n(N=!@[#6])c1[NH2],C=Nn1c([NH2])nc(c2ccccc2)c1c1ccccc1 +1494,Phenol_sulfite_A,C(c1ccc([OH1])cc1)(c2ccc([OH1])cc2)OS(=[OX1])=[OX1],O=S(=O)OC(c1ccc([OH])cc1)c1ccc([OH])cc1 +1495,Pyrazole_amino_A,"[#6]1=,:[#6]([NH2])-,:[#7]-,:[#7]=,:[#6]1-[#6]2=,:[#6]([CH2,CH3])-,:[#8]-,:[#6!H0]=,:[#6!H0]2",*C1=C(C2=NNC([NH2])=C2)C=CO1 +1496,Pyrazole_amino_B,"[#16]1-,:[#6]=,:[#6]-,:[#7]=,:[#6]1-[#6]6-,:[#6!H0]=,:[#7]-,:[#7!H0]-,:[#6]([NH2])=,:6",[NH2]C1=C(C2=NC=CS2)C=NN1 +1497,Indole_3yl_alk_B,"c12[cH][cH][cH][cH]c1-,:[#6]([CH2,CH3])=,:[#6](-cc)-,:[#7]2-!@cc",*C1=C(cc)N(cc)c2[cH][cH][cH][cH]c21 +1498,Mannich_B,"c1c[cH]c2O[CH2]N(ccO[CH2,CH3])[CH2]c2[cH]1",*OccN1[CH2]Oc2[cH]cc[cH]c2[CH2]1 +1499,Mannich_catechol_A,"[cH]1c([#8])c([#8])[cH]c2c1O[CH2]N([CH2,CH3])[CH2]2",*N1[CH2]Oc2[cH]c(O)c(O)[cH]c2[CH2]1 +1500,Dyes7A,"c1ccccc1N([CH2,CH3])[C!H0]=[C!H0]C=!@[C!H0][C!H0]=CC=&@Nc2ccccc2",*N(C=CC=CC=CC=Nc1ccccc1)c1ccccc1 +1501,Misc_imidazole,"[C!H0](c1[cH][cH]c(Cl)[cH][cH]1)(c2[cH][cH]c(Cl)[cH][cH]2)O[CH2][CH2][CH2][#6]3-,:[#7]([CH3])-,:[#6!H0]=,:[#6!H0]-,:[#7]=,:3",[CH3]N1C=CN=C1[CH2][CH2][CH2]OC(c1[cH][cH]c(Cl)[cH][cH]1)c1[cH][cH]c(Cl)[cH][cH]1 +1502,Het_thio_N_5C,"cc[N!H0]C(=[OX1])[#6]1-,:[#7]=,:[#7]-,:[#16]-,:[#6]([N!H0]cc)=,:1",ccNC(=O)C1=C(Ncc)SN=N1 +1503,Valproic acid derivatives,[OH1][CX3](=[OX1])[CX4H1]([CX4H2]-C~[#6])([CX4H2]-C~[#6]),C~C[CH2][CH]([CH2]C~C)C(=O)[OH] +1504,Retinoic acid derivatives_1,"[$([OH1][CX3](=[OX1])c1[cH][cH]c(-c2c[cH]c3[cH]c([H,CX4])c([H,CX4])[cH]c3[cH]2)[cH][cH]1),$([OH1][CX3](=[OX1])c1[cH]c2[cH]cc(-c3[cH]c([H,CX4])c([H,CX4])[cH][cH]3)[cH]c2[cH][cH]1)]",* +1505,Thiazole_amine_I,"[CH2,CH3][N!H0]C=N[N!H0][#6]1=,:[#7]-,:[#6](-cc)=,:[#6!H0]-,:[#16]1",*NC=NNC1=NC(cc)=CS1 +1506,Indol_3yl_alk,"[H,CH2,CH3][#7]1-,:[#6]([CH2,CH3,$([a!c](:[#6]-,:[#7])),$([C!H0][#7]),$([C!H0]([CH2,CH3])[N!H0][CH2,CH3]),$([C!H0]([CH2,CH3])[CH2][N!H0][CH2,CH3])])=,:[#6]([CX4!H0])-,:c2[cH]cccc12",*C1=C(C)c2[cH]cccc2N1* +1507,Tetrazole_hzide,"a1aaa(aa1)[C!H0]=[C!H0]C(=[OX1])[N!H0][N!H0][#6]2=,:[#7]-,:[#7]=,:[#7]-,:[#7]2[#6]",CN1N=NN=C1NNC(=O)C=C*1:*:*:*:*:*:1 +1508,Three-membered heterocycles (LS),[!#6!#1]1~*~*~1,*1~*~*~1 +1509,Three-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~1,*1~C~C~1 +1510,Saturated three-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-1,*1CC1 +1511,Unsaturated three-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1~[#6]=[#6]~1),$([!#1!#6]1=[#6]~[#6]~1)]",* +1512,Three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[#6]~1,*1~*~C~1 +1513,Saturated three-membered heterocycles with two heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[#6]-1,*1*C1 +1514,Unsaturated three-membered heterocycles with two heteroatoms (LS),"[$([!#1!#6]1=[!#1!#6]~[#6]~1),$([!#1!#6]1~[!#6!#1]=[#6]~1)]",* +1515,Three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~1,*1~*~*~1 +1516,Saturated three-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-1,*1**1 +1517,Unsaturated three-membered heterocycles with three heteroatoms (LS),[!#1!#6]1~[!#1!#6]=[!#1!#6]~1,*1~*=*~1 +1518,Three-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~1,*1~*~*~1 +1519,Three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6&R1]~[#6&R1]~1,*1~C~C~1 +1520,Saturated three-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6&R1]-[#6&R1]-1,*1CC1 +1521,Aziridines (HS),[#7R1]1-[#6R1]-[#6R1]-1,C1CN1 +1522,Oxiranes (HS),[#8R1]1-[#6R1]-[#6R1]-1,C1CO1 +1523,Thiiranes (HS),[#16X2R1]1-[#6R1]-[#6R1]-1,C1CS1 +1524,Unsaturated three-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1~[#6R1]=[#6R1]~1),$([!#1!#6;R1]1=[#6R1]~[#6R1]~1)]",* +1525,Azirines (HS),"[$([#7R1]1-[#6R1]=[#6R1]-1),$([#7R1]1=[#6R1]-[#6R1]-1)]",* +1526,1H-Azirines (HS),[#7R1]1-[#6R1]=[#6R1]-1,C1=CN1 +1527,2H-Azirines (HS),[#7R1]1=[#6R1]-[#6R1]-1,C1=NC1 +1528,Oxirenes (HS),[#8R1]1-[#6R1]=[#6R1]-1,C1=CO1 +1529,Thiirenes (HS),[#16X2R1]1-[#6R1]=[#6R1]-1,C1=CS1 +1530,Three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~1,*1~*~C~1 +1531,Saturated three-membered heterocycles with two heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-1,*1*C1 +1532,Diaziridines (HS),[#7R1]1-[#7R1]-[#6R1]-1,C1NN1 +1533,Dioxiranes (HS),[#8R1]1-[#8R1]-[#6R1]-1,C1OO1 +1534,Oxaziridines (HS),[#8R1]1-[#7R1]-[#6R1]-1,C1NO1 +1535,Thiaziridines (HS),[#16X2R1]1-[#7R1]-[#6R1]-1,C1NS1 +1536,Unsaturated three-membered heterocycles with two heteroatoms (HS),"[$([!#1!#6;R1]1=[!#1!#6;R1]~[#6R1]~1),$([!#1!#6;R1]1~[!#6!#1;R1]=[#6R1]~1)]",* +1537,1H-Diazirenes (HS),[#7R1]1-[#7R1]=[#6R1]-1,C1=NN1 +1538,3H-Diazirenes (HS),[#7R1]1=[#7R1]-[#6R1]-1,C1N=N1 +1539,Oxazirenes (HS),[#7R1]1=[#6R1]-[#8R1]-1,C1=NO1 +1540,Thiazerenes (HS),[#7R1]1=[#6R1]-[#16X2R1]-1,C1=NS1 +1541,Three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~1 +1542,Saturated three-membered heterocycles with three heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**1 +1543,Triaziridines (HS),[#7R1]1-[#7R1]-[#7R1]-1,N1NN1 +1544,Trioxiranes (HS),[#8R1]1-[#8R1]-[#8R1]-1,O1OO1 +1545,Trithiiranes (HS),[#16X2R1]1-[#16X2R1]-[#16X2R1]1,S1SS1 +1546,Oxadiaziridines (HS),[#8R1]1-[#7R1]-[#7R1]1,N1NO1 +1547,Dioxaziridines (HS),[#8R1]1-[#8R1]-[#7R1]1,N1OO1 +1548,Thiodiaziridines (HS),[#16X2R1]1-[#7R1]-[#7R1]1,N1NS1 +1549,Dithiaziridines (HS),[#16X2R1]1-[#16X2R1]-[#7R1]1,N1SS1 +1550,Unsaturated three-membered heterocycles with three heteroatoms (HS),[!#1!#6;R1]1-[!#6!#1;R1]=[!#6!#1;R1]1,*1*=*1 +1551,1H-Triazirene (HS),[#7R1]1-[#7R1]=[#7R1]1,N1N=N1 +1552,Oxadiazirenes (HS),[#7R1]1=[#7R1]-[#8R1]1,N1=NO1 +1553,Thiodiazirenes (HS),[#7R1]1=[#7R1]-[#16X2R1]1,N1=NS1 +1554,Four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~1)]",* +1555,Saturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1-[!#6!#1]-[#6]-[#6]-1),$([!#6!#1]1-[#6]-[!#6!#1]-[#6]-1)]",* +1556,Unsaturated four-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]=[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]=[#6]~1),$([!#6!#1]1=[#6]~[!#6!#1]~[#6]~1)]",* +1557,Four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~C~*~1 +1558,Saturated four-membered heterocycles with three heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[#6]-1,*1*C*1 +1559,Unsaturated four-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]=[#6]~1)]",* +1560,Four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~1 +1561,Saturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1***1 +1562,Unsaturated four-membered heterocycles with four heteroatoms (LS),[!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*=*~1 +1563,Four-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~1 +1564,Four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~1 +1565,Saturated four-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1-[#6R1]-[#6R1]-[#6R1]-1,*1CCC1 +1566,Azetidines (HS),[#7R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CNC1 +1567,Oxetanes (HS),[#8R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1COC1 +1568,Thietanes (HS),[#16X2R1]1-[#6R1]-[#6R1]-[#6R1]-1,C1CSC1 +1569,Unsaturated four-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]=[#6R1]~[#6R1]~1)]",* +1570,Azetines (HS),"[$([#7R1]1=[#6R1]-[#6R1]-[#6R1]-1),$([#7R1]1-[#6R1]=[#6R1]-[#6R1]-1)]",* +1571,1-Azetines (HS),[#7R1]1=[#6R1]-[#6R1]-[#6R1]-1,C1=NCC1 +1572,2-Azetines (HS),[#7R1]1-[#6R1]=[#6R1]-[#6R1]-1,C1=CNC1 +1573,Azetes (HS),[#7R1]1=[#6R1][#6R1]=[#6R1]1,C1=CN=C1 +1574,Oxetenes (HS),[#8R1]1[#6R1]=[#6R1][#6R1]1,C1C=CO1 +1575,Thietenes (HS),[#16X2R1]1[#6R1]=[#6R1][#6R1]1,C1C=CS1 +1576,Four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1577,Saturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1-[!#6!#1;R1]-[#6R1]-[#6R1]-1),$([!#6!#1;R1]1-[#6R1]-[!#6!#1;R1]-[#6R1]-1)]",* +1578,Diazetidines (HS),"[$([NR1]1[CR1][CR1][NR1]1),$([NR1]1[CR1][NR1][CR1]1)]",* +1579,"1,2-Diazetidines (HS)",[NR1]1[CR1][CR1][NR1]1,C1CNN1 +1580,"1,3-Diazetidines (HS)",[NR1]1[CR1][NR1][CR1]1,C1NCN1 +1581,Dioxetanes (HS),"[$([OR1]1[OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]1)]",* +1582,"1,2-Dioxetanes (HS)",[OR1]1[OR1][CR1][CR1]1,C1COO1 +1583,"1,3-Dioxetanes (HS)",[OR1]1[CR1][OR1][CR1]1,C1OCO1 +1584,Dithietanes (HS),"[$([SX2R1]1[SX2R1][CR1][CR1]1),$([SX2R1]1[CR1][SX2R1][CR1]1)]",* +1585,"1,2-Dithietanes (HS)",[SX2R1]1[SX2R1][CR1][CR1]1,C1CSS1 +1586,"1,3-Dithietanes (HS)",[SX2R1]1[CR1][SX2R1][CR1]1,C1SCS1 +1587,Unsaturated four-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]=[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]=[#6R1]~1),$([!#6!#1;R1]1=[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1588,Diazetines (HS),"[$([#7]1=,:[#7]-,:[#6]-,=,:[#6]-,:1),$([#7]1-,:[#7]=,:[#6]-,:[#6]-,=,:1),$([#7]1-,:[#7]-,:[#6]=,:[#6]-,=,:1),$([#7]1=,:[#6]-,:[#7]-,=,:[#6]-,:1)]",* +1589,Dioxetenes (HS),"[#8R1]1-,:[#8R1]-,:[#6R1]=,:[#6R1]-,:1",C1=COO1 +1590,Dithietenes (HS),"[#16R1]1-,:[#16R1]-,:[#6R1]=,:[#6R1]-,:1",C1=CSS1 +1591,Four-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~1,*1~C~C~C~1 +1592,Saturated four-membered heterocycles with one heteroatom (LS),[!#6!#1]1-[#6]-[#6]-[#6]-1,*1CCC1 +1593,Unsaturated four-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]=[#6]~[#6]~1)]",* +1594,Diazirenes (HS),"[$([#7R1]1-[#7R1]=[#6R1]-1),$([#7R1]1=[#7R1]-[#6R1]-1)]",* +1595,Four-membered heterocycles (LS),[!#6!#1]1~*~*~*~1,*1~*~*~*~1 +1596,Five-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~1,*1~*~*~*~*~1 +1597,Five-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~1 +1598,Saturated five-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCC1,*1CCCC1 +1599,Unsaturated five-membered heterocycles with one heteroatom (LS),"[$([!#6!#1]1=CCCC1),$([!#6!#1]1C=CCC1),$([!#6!#1]1CC=CC1),$([!#6!#1]1=CC=CC1);!$(n1cccc1)]",* +1600,Aromatic five-membered heterocycles with one heteroatom (LS),[a!#6]1cccc1,*1cccc1 +1601,Five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1602,Saturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCC1),$([!#6!#1]1C[!#6!#1]CC1)]",* +1603,Unsaturated five-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1]C-,=CC1),$([!#6!#1]1[!#6!#1]=CCC1),$([!#6!#1]1[!#6!#1]C=CC1),$([!#6!#1]1=C[!#6!#1]-,=CC1),$([!#6!#1]1C[!#6!#1]CC=1),$([!#6!#1]1C[!#6!#1]C=C1)]",* +1604,Aromatic five-membered heterocycles with two heteroatoms (LS),"[$([a!#6]1[a!#6]ccc1),$([a!#6]1c[a!#6]cc1)]",* +1605,Five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1606,Saturated five-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]C1)]",* +1607,Aromatic five-membered heterocycles with three heteroatoms (LS),"[$([a!#6]1[a!#6][a!#6]cc1),$([a!#6]1[a!#6]c[a!#6]c1)]",* +1608,Five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~1 +1609,Saturated five-membered heterocycles with four heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]C1,*1**C*1 +1610,Unsaturated five-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1=[!#6!#1][!#6!#1]-,=[!#6!#1][#6]1),$([!#6!#1]1[!#6!#1]=[!#6!#1][!#6!#1][#6]1),$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1][#6]=1)]",* +1611,Aromatic five-membered heterocycles with four heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6]c1,*1:*:*c*:1 +1612,Five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~1 +1613,Saturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1****1 +1614,Unsaturated five-membered heterocycles with five heteroatoms (LS),[!#6!#1]1=[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1**=**1 +1615,Aromatic five-membered heterocycles with five heteroatoms (LS),[a!#6]1[a!#6][a!#6][a!#6][a!#6]1,*1:*:*:*:*:1 +1616,Five-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~1 +1617,Five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~1 +1618,Saturated five-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1]1,*1CCCC1 +1619,Pyrrolidines (HS),[NR1]1[CR1][CR1][CR1][CR1]1,C1CCNC1 +1620,Tetrahydrofurans (HS),[OR1]1[CR1][CR1][CR1][CR1]1,C1CCOC1 +1621,Tetrahydrothiophenes (HS),[SR1]1[CR1][CR1][CR1][CR1]1,C1CCSC1 +1622,Unsaturated five-membered heterocycles with one heteroatom (HS),"[$([!#6!#1;R1]1=[CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1]=[CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1]=[CR1][CR1]1),$([!#6!#1;R1]1=[CR1][CR1]=[CR1][CR1]1);!$(n1cccc1)]",* +1623,Pyrrolines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1624,1-Pyrrolines (HS),[NR1]1=[CR1][CR1][CR1][CR1]1,C1CC=NC1 +1625,2-Pyrrolines (HS),[NR1]1[CR1]=[CR1][CR1][CR1]1,C1CNC=C1 +1626,3-Pyrrolines (HS),[NR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCN1 +1627,Dihydrofurans (HS),"[$([OR1]1[CR1]=[CR1][CR1][CR1]1),$([OR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1628,"2,3-Dihydrofurans (HS)",[OR1]1[CR1]=[CR1][CR1][CR1]1,C1COC=C1 +1629,"2,5-Dihydrofurans (HS)",[OR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCO1 +1630,Dihydrothiophenes (HS),"[$([SR1]1[CR1]=[CR1][CR1][CR1]1),$([SR1]1[CR1][CR1]=[CR1][CR1]1)]",* +1631,"2,3-Dihydrothiophenes (HS)",[SR1]1[CR1]=[CR1][CR1][CR1]1,C1CSC=C1 +1632,"2,5-Dihydrothiophenes (HS)",[SR1]1[CR1][CR1]=[CR1][CR1]1,C1C=CCS1 +1633,Aromatic five-membered heterocycles with one heteroatom (HS),[a!#6;R1]1[cR1][cR1][cR1][cR1]1,*1cccc1 +1634,Pyrroles (HS),[nR1]1[cR1][cR1][cR1][cR1]1,c1ccnc1 +1635,Furans (HS),[oR1]1[cR1][cR1][cR1][cR1]1,c1ccoc1 +1636,Thiophenes (HS),[sR1]1[cR1][cR1][cR1][cR1]1,c1ccsc1 +1637,Indoles,[cR1]1[cR1][cR1][cR1][cR2]2[nR1][cR1][cR1][cR2]12,c1ccc2nccc2c1 +1638,Benzofurans,[cR1]1[cR1][cR1][cR1][cR2]2[oR1][cR1][cR1][cR2]12,c1ccc2occc2c1 +1639,Benzothiophenes,[cR1]1[cR1][cR1][cR1][cR2]2[sR1][cR1][cR1][cR2]12,c1ccc2sccc2c1 +1640,Five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1)]",* +1641,Saturated five-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1]1)]",* +1642,Diazolidines (HS),"[$([NR1]1[NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1]1)]",* +1643,Pyrazolidines (HS),[NR1]1[NR1][CR1][CR1][CR1]1,C1CNNC1 +1644,Imidazolidines (HS),[NR1]1[CR1][NR1][CR1][CR1]1,C1CNCN1 +1645,Dioxolanes (HS),"[$([OR1]1[OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1]1)]",* +1646,"1,2-Dioxolanes (HS)",[OR1]1[OR1][CR1][CR1][CR1]1,C1COOC1 +1647,"1,3-Dioxolanes (HS)",[OR1]1[CR1][OR1][CR1][CR1]1,C1COCO1 +1648,Dithiolanes (HS),"[$([SR1]1[SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1]1)]",* +1649,"1,2-Dithiolanes (HS)",[SR1]1[SR1][CR1][CR1][CR1]1,C1CSSC1 +1650,"1,3-Dithiolanes (HS)",[SR1]1[CR1][SR1][CR1][CR1]1,C1CSCS1 +1651,Pyrazolines (HS),"[$([NR1]1=[NR1][CR1][CR1][CR1]1),$([NR1]1[NR1]=[CR1][CR1][CR1]1),$([NR1]1[NR1][CR1]=[CR1][CR1]1)]",* +1652,1-Pyrazolines (HS),[NR1]1=[NR1][CR1][CR1][CR1]1,C1CN=NC1 +1653,2-Pyrazolines (HS),[NR1]1[NR1]=[CR1][CR1][CR1]1,C1CNN=C1 +1654,Imidazolines (HS),"[$([NR1]1=[CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1]=[CR1][CR1]1),$([NR1]1[CR1][NR1][CR1]=[CR1]1)]",* +1655,2-Imidazolines (HS),[NR1]1=[CR1][NR1][CR1][CR1]1,C1CN=CN1 +1656,3-Imidazolines (HS),[NR1]1[CR1][NR1]=[CR1][CR1]1,C1C=NCN1 +1657,4-Imidazolines (HS),[NR1]1[CR1][NR1][CR1]=[CR1]1,C1NC=CN1 +1658,Dioxolenes (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]1),$([OR1]1[CR1][OR1][CR1]=[CR1]1)]",* +1659,"1,2-Dioxolenes (HS)",[OR1]1[OR1][CR1]=[CR1][CR1]1,C1C=COO1 +1660,"1,3-Dioxolenes (HS)",[OR1]1[CR1][OR1][CR1]=[CR1]1,C1OC=CO1 +1661,Dithiolenes (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]1),$([SR1]1[CR1][SR1][CR1]=[CR1]1)]",* +1662,"1,2-Dithiolenes (HS)",[SR1]1[SR1][CR1]=[CR1][CR1]1,C1C=CSS1 +1663,"1,3-Dithiolenes (HS)",[SR1]1[CR1][SR1][CR1]=[CR1]1,C1SC=CS1 +1664,Aromatic five-membered heterocycles with two heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][cR1][cR1][cR1]1),$([a!#6;R1]1[cR1][a!#6;R1][cR1][cR1]1)]",* +1665,Diazoles (HS),"[$([nR1]1[nR1][cR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][cR1]1)]",* +1666,Pyrazoles (HS),[nR1]1[nR1][cR1][cR1][cR1]1,c1cnnc1 +1667,Imidazoles (HS),[nR1]1[cR1][nR1][cR1][cR1]1,c1cncn1 +1668,Oxazoles (HS),"[$([oR1]1[nR1][cR1][cR1][cR1]1),$([oR1]1[cR1][nR1][cR1][cR1]1)]",* +1669,"1,2-Oxazoles (HS)",[oR1]1[nR1][cR1][cR1][cR1]1,c1cnoc1 +1670,"1,3-Oxazoles (HS)",[oR1]1[cR1][nR1][cR1][cR1]1,c1cocn1 +1671,Thiazoles (HS),"[$([sR1]1[nR1][cR1][cR1][cR1]1),$([sR1]1[cR1][nR1][cR1][cR1]1)]",* +1672,"1,2-Thiazoles (HS)",[sR1]1[nR1][cR1][cR1][cR1]1,c1cnsc1 +1673,"1,3-Thiazoles (HS)",[sR1]1[cR1][nR1][cR1][cR1]1,c1cscn1 +1674,Five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1675,Saturated five-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1676,Triazolidines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1]1)]",* +1677,"1,2,3-Triazolidines (HS)",[NR1]1[NR1][NR1][CR1][CR1]1,C1CNNN1 +1678,"1,2,4-Triazolidines (HS)",[NR1]1[NR1][CR1][NR1][CR1]1,C1NCNN1 +1679,Trioxolanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1]1)]",* +1680,"1,2,3-Trioxolanes (HS)",[OR1]1[OR1][OR1][CR1][CR1]1,C1COOO1 +1681,"1,2,4-Trioxolanes (HS)",[OR1]1[OR1][CR1][OR1][CR1]1,C1OCOO1 +1682,Trithiolanes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1]1)]",* +1683,"1,2,3-Trithiolanes (HS)",[SR1]1[SR1][SR1][CR1][CR1]1,C1CSSS1 +1684,"1,2,4-Trithiolanes (HS)",[SR1]1[SR1][CR1][SR1][CR1]1,C1SCSS1 +1685,"1,2,3-Triazolines (HS)","[$([NR1]1=[NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][NR1][CR1][CR1]=1),$([NR1]1[NR1][NR1][CR1]=[CR1]1)]",* +1686,"1,2,4-Triazolines (HS)","[$([NR1]1=[NR1][CR1][NR1][CR1]1),$([NR1]1[NR1]=[CR1][NR1][CR1]1),$([NR1]1[NR1][CR1]=[NR1][CR1]1)]",* +1687,"1,2,3-Trioxoles (HS)",[OR1]1[OR1][OR1][CR1]=[CR1]1,C1=COOO1 +1688,"1,2,3-Trithioles (HS)",[SR1]1[SR1][SR1][CR1]=[CR1]1,C1=CSSS1 +1689,Aromatic five-membered heterocycles with three heteroatoms (HS),"[$([a!#6;R1]1[a!#6;R1][a!#6;R1][cR1][cR1]1),$([a!#6;R1]1[a!#6;R1][cR1][a!#6;R1][cR1]1)]",* +1690,Triazoles (HS),"[$([nR1]1[nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1]1)]",* +1691,"1,2,3-Triazoles (HS)",[nR1]1[nR1][nR1][cR1][cR1]1,c1cnnn1 +1692,"1,2,4-Triazoles (HS)",[nR1]1[nR1][cR1][nR1][cR1]1,c1ncnn1 +1693,Oxadiazoles (HS),"[$([oR1]1[nR1][nR1][cR1][cR1]1),$([oR1]1[nR1][cR1][nR1][cR1]1),$([oR1]1[nR1][cR1][cR1][nR1]1),$([oR1]1[cR1][nR1][nR1][cR1]1)]",* +1694,"1,2,3-Oxadiazoles (HS)",[oR1]1[nR1][nR1][cR1][cR1]1,c1conn1 +1695,"1,2,4-Oxadiazoles (HS)",[oR1]1[nR1][cR1][nR1][cR1]1,c1ncon1 +1696,"1,2,5-Oxadiazoles (furazanes) (HS)",[oR1]1[nR1][cR1][cR1][nR1]1,c1cnon1 +1697,"1,3,4-Oxadiazoles (HS)",[oR1]1[cR1][nR1][nR1][cR1]1,c1nnco1 +1698,Five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~1 +1699,Saturated five-membered heterocycles with four heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1][CR1]1,*1**C*1 +1700,Tetrazolidines (HS),[NR1]1[NR1][NR1][NR1][CR1]1,C1NNNN1 +1701,Tetraoxolanes (HS),[OR1]1[OR1][OR1][OR1][CR1]1,C1OOOO1 +1702,Tetrathiolanes (HS),[SR1]1[SR1][SR1][SR1][CR1]1,C1SSSS1 +1703,Unsaturated five-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1=[!#6!#1;R1][!#6!#1;R1]-,=[!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1]=[!#6!#1;R1][!#6!#1;R1][#6R1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][#6R1]=1)]",* +1704,Aromatic five-membered heterocycles with four heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][cR1]1,*1:*:*c*:1 +1705,Tetrazoles (HS),[nR1]1[nR1][nR1][nR1][cR1]1,c1nnnn1 +1706,Oxatriazoles (HS),"[$([oR1]1[nR1][nR1][nR1][cR1]1),$([oR1]1[nR1][nR1][cR1][nR1]1)]",* +1707,"1,2,3,4-Oxatriazoles (HS)",[oR1]1[nR1][nR1][nR1][cR1]1,c1nnno1 +1708,"1,2,3,5-Oxatriazoles (HS)",[oR1]1[nR1][nR1][cR1][nR1]1,c1nnon1 +1709,Thiatriazoles (HS),"[$([sR1]1[nR1][nR1][nR1][cR1]1),$([sR1]1[nR1][nR1][cR1][nR1]1)]",* +1710,"1,2,3,4-Thiatriazoles (HS)",[sR1]1[nR1][nR1][nR1][cR1]1,c1nnns1 +1711,"1,2,3,5-Thiatriazoles (HS)",[sR1]1[nR1][nR1][cR1][nR1]1,c1nnsn1 +1712,Five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~1 +1713,Saturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1****1 +1714,Pentazolidines (HS),[NR1]1[NR1][NR1][NR1][NR1]1,N1NNNN1 +1715,Pentaoxolanes (HS),[OR1]1[OR1][OR1][OR1][OR1]1,O1OOOO1 +1716,Pentathiolanes (HS),[SR1]1[SR1][SR1][SR1][SR1]1,S1SSSS1 +1717,Unsaturated five-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1=[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1**=**1 +1718,Aromatic five-membered heterocycles with five heteroatoms (HS),[a!#6;R1]1[a!#6;R1][a!#6;R1][a!#6;R1][a!#6;R1]1,*1:*:*:*:*:1 +1719,Pentazoles,[nR1]1[nR1][nR1][nR1][nR1]1,n1nnnn1 +1720,Six-membered heterocycles (LS),[!#6!#1]1~*~*~*~*~*~1,*1~*~*~*~*~*~1 +1721,Six-membered heterocycles with one heteroatom (LS),[!#6!#1]1~[#6]~[#6]~[#6]~[#6]~[#6]~1,*1~C~C~C~C~C~1 +1722,Saturated six-membered heterocycles with one heteroatom (LS),[!#6!#1]1CCCCC1,*1CCCCC1 +1723,Unsaturated six-membered heterocycles with one heteroatom (LS),"[$([!#1!#6]1=C~C~C~C~C~1),$([!#1!#6]1~C=C~C~C~C~1),$([!#1!#6]1~C~C=C~C~C~1);!$([a!c]1ccccc1)]",* +1724,Aromatic six-membered heterocycles with one heteroatom (LS),[a!c]1ccccc1,*1ccccc1 +1725,Six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[#6]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[#6]~[!#6!#1]~[#6]~[#6]~1)]",* +1726,Saturated six-membered heterocycles with two heteroatoms (LS),"[$([!#6!#1]1[!#6!#1]CCCC1),$([!#6!#1]1C[!#6!#1]CCC1),$([!#6!#1]1CC[!#6!#1]CC1)]",* +1727,Aromatic six-membered heterocycles with two heteroatoms (LS),"[$([a!c]1[a!c]cccc1),$([a!c]1c[a!c]ccc1),$([a!c]1cc[a!c]cc1)]",* +1728,Six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[#6]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1)]",* +1729,Saturated six-membered heterocycles with three heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1]CCC1),$([!#6!#1]1[!#6!#1]C[!#6!#1]CC1),$([!#6!#1]1C[!#6!#1]C[!#6!#1]C1)]",* +1730,Aromatic six-membered heterocycles with three heteroatoms (LS),"[$([a!c]1[a!c][a!c]ccc1),$([a!c]1[a!c]c[a!c]cc1),$([a!c]1c[a!c]c[a!c]c1)]",* +1731,Six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[!#6!#1]~[#6]~[!#6!#1]~[#6]~1),$([!#6!#1]1~[!#6!#1]~[#6]~[!#6!#1]~[!#6!#1]~[#6]~1)]",* +1732,Saturated six-membered heterocycles with four heteroatoms (LS),"[$([!#6!#1]1[!#6!#1][!#6!#1][!#6!#1]CC1),$([!#6!#1]1[!#6!#1][!#6!#1]C[!#6!#1]C1),$([!#6!#1]1[!#6!#1]C[!#6!#1][!#6!#1]C1)]",* +1733,Aromatic six-membered heterocycles with four heteroatoms (LS),"[$([a!c]1[a!c][a!c][a!c]cc1),$([a!c]1[a!c][a!c]c[a!c]c1),$([a!c]1[a!c]c[a!c][a!c]c1)]",* +1734,Six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[#6]~1,*1~*~*~C~*~*~1 +1735,Saturated six-membered heterocycles with five heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-C-1,*1**C**1 +1736,Aromatic six-membered heterocycles with five heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c]c1,*1:*:*c*:*:1 +1737,Saturated six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-[!#6!#1]-1,*1*****1 +1738,Unsaturated six-membered heterocycles with six heteroatoms (LS),[$([!#6!#1]1=[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1739,Aromatic six-membered heterocycles with six heteroatoms (LS),[a!c]1[a!c][a!c][a!c][a!c][a!c]1,*1:*:*:*:*:*:1 +1740,Six-membered heterocycles (HS),[!#6!#1;R1]1~[*R1]~[*R1]~[*R1]~[*R1]~[*R1]~1,*1~*~*~*~*~*~1 +1741,Six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1~[#6R1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1,*1~C~C~C~C~C~1 +1742,Saturated six-membered heterocycles with one heteroatom (HS),[!#6!#1;R1]1[CR1][CR1][CR1][CR1][CR1]1,*1CCCCC1 +1743,Piperidines (HS),[NR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCNCC1 +1744,Tetrahydropyrans (HS),[OR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCOCC1 +1745,Tetrahydrothiopyrans (HS),[SR1]1[CR1][CR1][CR1][CR1][CR1]1,C1CCSCC1 +1746,Unsaturated six-membered heterocycles with one heteroatom (HS),"[$([!#1!#6;R1]1=[CR1]~[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]=[CR1]~[CR1]~[CR1]~[CR1]~1),$([!#1!#6;R1]1~[CR1]~[CR1]=[CR1]~[CR1]~[CR1]~1);!$([a!c]1ccccc1)]",* +1747,Tetrahydropyridines (HS),"[$([NR1]1=[CR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1]=[CR1][CR1][CR1]1)]",* +1748,Dihydropyridines (HS),"[$([NR1]1=[CR1][CR1]-,=[CR1]-,=[CR1][CR1]1),$([NR1]1[CR1]=[CR1][CR1][CR1]-,=[CR1]-,=1),$([NR1]1[CR1]=[CR1][CR1]=[CR1][CR1]1)]",* +1749,Pyrans (HS),"[OR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=COC1 +1750,Thiopyrans (HS),"[SR1]1[CR1]=[CR1][CR1]-,=[CR1]-,=[CR1]1",C1CC=CSC1 +1751,Aromatic six-membered heterocycles with one heteroatom (HS),[a!c;R1]1[cR1][cR1][cR1][cR1][cR1]1,*1ccccc1 +1752,Pyridines (HS),[nR1]1[cR1][cR1][cR1][cR1][cR1]1,c1ccncc1 +1753,Six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[#6R1]~[!#6!#1]~[#6R1]~[#6R1]~1)]",* +1754,Saturated six-membered heterocycles with two heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][CR1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][CR1][!#6!#1;R1][CR1][CR1]1)]",* +1755,Hexahydrodiazines,"[$([NR1]1[NR1][CR1][CR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][CR1][CR1]1),$([NR1]1[CR1][CR1][NR1][CR1][CR1]1)]",* +1756,Dioxanes,"[$([OR1]1[OR1][CR1][CR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][CR1][CR1]1),$([OR1]1[CR1][CR1][OR1][CR1][CR1]1)]",* +1757,Dithianes,"[$([SR1]1[SR1][CR1][CR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][CR1][CR1]1),$([SR1]1[CR1][CR1][SR1][CR1][CR1]1)]",* +1758,Dioxines (HS),"[$([OR1]1[OR1][CR1]=[CR1][CR1]=[CR1]1),$([OR1]1[CR1]=[CR1][OR1][CR1]=[CR1]1)]",* +1759,Aromatic six-membered heterocycles with two heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][cR1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[cR1][cR1][a!c;R1][cR1][cR1]1)]",* +1760,Pyridazines (HS),[nR1]1[nR1][cR1][cR1][cR1][cR1]1,c1ccnnc1 +1761,Pyrimidines (HS),[nR1]1[cR1][nR1][cR1][cR1][cR1]1,c1cncnc1 +1762,Pyrazines (HS),[nR1]1[cR1][cR1][nR1][cR1][cR1]1,c1cnccn1 +1763,Six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~[#6R1]~1),$([!#6!#1;R1]1~[#6R1]~[!#6!#1;R1]~[#6R1]~[!#6!#1;R1]~[#6R1]~1)]",* +1764,Saturated six-membered heterocycles with three heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[CR1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1)]",* +1765,Hexahydrotriazines (HS),"[$([NR1]1[NR1][NR1][CR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][CR1][CR1]1),$([NR1]1[CR1][NR1][CR1][NR1][CR1]1)]",* +1766,Trioxanes (HS),"[$([OR1]1[OR1][OR1][CR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][CR1][CR1]1),$([OR1]1[CR1][OR1][CR1][OR1][CR1]1)]",* +1767,Trithianes (HS),"[$([SR1]1[SR1][SR1][CR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][CR1][CR1]1),$([SR1]1[CR1][SR1][CR1][SR1][CR1]1)]",* +1768,Aromatic six-membered heterocycles with three heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][cR1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[cR1][a!c;R1][cR1][a!c;R1][cR1]1)]",* +1769,Triazines (HS),"[$([nR1]1[nR1][nR1][cR1][cR1][cR1]1),$([nR1]1[nR1][cR1][nR1][cR1][cR1]1),$([nR1]1[cR1][nR1][cR1][nR1][cR1]1)]",* +1770,Saturated six-membered heterocycles with four heteroatoms (HS),"[$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][!#6!#1;R1][CR1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][!#6!#1;R1][CR1][!#6!#1;R1][CR1]1),$([!#6!#1;R1]1[!#6!#1;R1][CR1][!#6!#1;R1][!#6!#1;R1][CR1]1)]",* +1771,Hexahydrotetrazines (HS),"[$([NR1]1[NR1][NR1][NR1][CR1][CR1]1),$([NR1]1[NR1][CR1][NR1][NR1][CR1]1),$([NR1]1[NR1][NR1][CR1][NR1][CR1]1)]",* +1772,Tetroxanes (HS),"[$([OR1]1[OR1][OR1][OR1][CR1][CR1]1),$([OR1]1[OR1][CR1][OR1][OR1][CR1]1)]",* +1773,Tetrathianes (HS),"[$([SR1]1[SR1][SR1][SR1][CR1][CR1]1),$([SR1]1[SR1][CR1][SR1][SR1][CR1]1)]",* +1774,Aromatic six-membered heterocycles with four heteroatoms (HS),"[$([a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][cR1][cR1]1),$([a!c;R1]1[a!c;R1][a!c;R1][cR1][a!c;R1][cR1]1),$([a!c;R1]1[a!c;R1][cR1][a!c;R1][a!c;R1][cR1]1)]",* +1775,Tetrazines (HS),"[$([nR1]1[nR1][nR1][nR1][cR1][cR1]1),$([nR1]1[nR1][nR1][cR1][nR1][cR1]1),$([nR1]1[nR1][cR1][nR1][nR1][cR1]1)]",* +1776,Six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[#6R1]~1,*1~*~*~C~*~*~1 +1777,Saturated six-membered heterocycles with five heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[CR1]-1,*1**C**1 +1778,Aromatic six-membered heterocycles with five heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][cR1]1,*1:*:*c*:*:1 +1779,Pentazines,[nR1]1[nR1][nR1][nR1][nR1][cR1]1,c1nnnnn1 +1780,Six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1,*1~*~*~*~*~*~1 +1781,Saturated six-membered heterocycles with six heteroatoms (HS),[!#6!#1;R1]1-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-[!#6!#1;R1]-1,*1*****1 +1782,Unsaturated six-membered heterocycles with six heteroatoms (HS),[$([!#6!#1;R1]1=[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~[!#6!#1;R1]~1);!$([a!c]1[a!c][a!c][a!c][a!c][a!c]1)],* +1783,Aromatic six-membered heterocycles with six heteroatoms (HS),[a!c;R1]1[a!c;R1][a!c;R1][a!c;R1][a!c;R1][a!c;R1]1,*1:*:*:*:*:*:1 +1784,Hexazines,[nR1]1[nR1][nR1][nR1][nR1][nR1]1,n1nnnnn1 +1785,Six-membered heterocycles with six heteroatoms (LS),[!#6!#1]1~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~[!#6!#1]~1,*1~*~*~*~*~*~1 +1786,Dithiines (HS),"[$([SR1]1[SR1][CR1]=[CR1][CR1]=[CR1]1),$([SR1]1[CR1]=[CR1][SR1][CR1]=[CR1]1)]",* +1787,Hexahydropentazines (HS),[NR1]1[NR1][NR1][NR1][NR1][CR1]1,C1NNNNN1 +1788,Pentoxanes (HS),[OR1]1[OR1][OR1][OR1][OR1][CR1]1,C1OOOOO1 +1789,Pentathianes (HS),[SR1]1[SR1][SR1][SR1][SR1][CR1]1,C1SSSSS1 +1790,"Cumulated alkadienes (1,2-alkadienes)",[CX3]=[CX2]=[CX3],C=C=C +1791,Allyl halides,"[CX3]=[CX3][CX4][F,Cl,Br,I]",*CC=C +1792,Allyl fluorides,[CX3]=[CX3][CX4]F,C=CCF +1793,Allyl chlorides,[CX3]=[CX3][CX4]Cl,C=CCCl +1794,Allyl bromides,[CX3]=[CX3][CX4]Br,C=CCBr +1795,Allyl iodides,[CX3]=[CX3][CX4]I,C=CCI +1796,Vinyl fluorides,F[CX3]=[CX3],C=CF +1797,Vinyl chlorides,Cl[CX3]=[CX3],C=CCl +1798,Vinyl bromides,Br[CX3]=[CX3],C=CBr +1799,Vinyl iodides,I[CX3]=[CX3],C=CI +1800,Alkynyl fluorides,F[CX2]#[CX2],C#CF +1801,Alkynyl chlorides,Cl[CX2]#[CX2],C#CCl +1802,Alkynyl iodides,I[CX2]#[CX2],C#CI +1803,Alkynyl bromides,Br[CX2]#[CX2],C#CBr +1804,Dialkylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2][CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))]",CSC +1805,Alkylarylthioethers,"[CX4&!$([CX4]([SX2])([#7,O,S,F,Cl,Br,I,P]))][SX2]c",CSc +1806,Diarylthioethers,c[SX2&!$([SX2r3])]c,cSc +1807,"1,2 – Diphenols",c([OH1])c([OH1]),[OH]cc[OH] +1808,"1,3 – Diphenols",c([OH1])[aR1]c([OH1]),[OH]c*c[OH] +1809,"1,4 - Diphenols",c1([OH1])aac([OH1])aa1,[OH]c1*:*c([OH])*:*1 +1810,"1,2 – Dithiophenols",c([SH1])c([SH1]),[SH]cc[SH] +1811,"1,3 – Dithiophenols",c([SH1])[aR1]c([SH1]),[SH]c*c[SH] +1812,"1,4 – Dithiophenols",c1([SH1])aac([SH1])aa1,[SH]c1*:*c([SH])*:*1 +1813,"1,2 – Aminophenols","c([OH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[OH] +1814,"1,3 – Aminophenols","c([OH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[OH] +1815,"1,4 – Aminophenols","c1([OH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([OH])*:*1 +1816,"1,2 – Aminothiophenols","c([SH1])c[NX3]([#1,#6])[#1,#6]",*N(*)cc[SH] +1817,"1,3 – Aminothiophenols","c([SH1])[aR1]c[NX3]([#1,#6])[#1,#6]",*N(*)c*c[SH] +1818,"1,4 – Aminothiophenols","c1([SH1])aac([NX3]([#1,#6])[#1,#6])aa1",*N(*)c1*:*c([SH])*:*1 +1819,Alkynyl ethers,"[CX2]#[CX2][OX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",COC#C +1820,Alkynyl thioethers,"[CX2]#[CX2][SX2][#6&!$([CX4]([OX2])([#7,O,S,F,Cl,Br,I,P]))&!$([CX3]([OX2])=[OX1,SX1,NX2,C])]",CSC#C +1821,Carbonic acid esters,"[#1,#6&!$([CX3]=[OX1,SX1,NX2])][OX2][CX3](=[OX1])[OX2][#6&!$([CX3]=[OX1,SX1,NX2])]",*OC(=O)OC +1822,Phosphonic acid amides,[OX1]=[Pv5X4]([NX3])([#6])[!#6!$([SX2])],*P(C)(N)=O +1823,Aldehyde,[CX3H1](=O)[#6],C[CH]=O +1824,AliphaticEther,[!$(C=O);$([C&!a])][OX2&H0][!$(C=O);$([C&!a])],*O* +1825,AminoAcids,"[$([NX3,NX4+][CX4H]([*])[CX3](=[OX1])[O,N]),$([$([$([NX3H2,NX4H3+]),$([NX3H](C)(C))][CX4H2][CX3](=[OX1])[OX2H,OX1-,N])])]",* +1826,AromaticHalogen,"[$([a][F,Cl,I])]",* +1827,AromaticNGroups,"[$([a]N(~O)~O),$([a]N([#1])[*]),$([a]N([#1])[!#1])]",* +1828,AromaticSulphonicAcid,"[$([#16X4](=[OX1])(=[OX1])([a])[OX2H,OX1H0-]),$([#16X4+2]([OX1-])([OX1-])([a])[OX2H,OX1H0-])]",* +1829,AzoGroup,[$([!R&N]=[!R&N])],* +1830,CyanoGroupOnMoreThanEightAtomsChain,[N]#[C]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0]~[AR0],*~*~*~*~*~*~*~*~C#N +1831,Epoxide,[$(C1OC1)],* +1832,Esters,[#6][CX3](=O)[$([OX2H0]([#6])[#6])],*C(C)=O +1833,Formaldehyde,[CX3H2](=O),C=O +1834,Ketone,[C][C](=O)[C],CC(C)=O +1835,MoreThanTwoHydroxyOnAromaticRing,"[$([a&R]([OX2H])[a&R]([OX2H])),$([a&R]([OX2H])a[a&R]([OX2H])),$([a&R]([OX2H])aa[a&R]([OX2H]))]",* +1836,Nitrile,[C]#[N],C#N +1837,NNitroso,[$(NN=O)],* +1838,PyridineRing,[$(n1ccccc1)],* +1839,TerminalTertButyl,[$([C]([CH3])([CH3])([CH3])([*]))],* +1840,TertiaryAmine,[!R&NX3&H0],* +1841,TriazineRing,"[$(n1nnccc1),$(n1ncncc1),$(n1cncnc1)]",* +1842,Trifluoromethyl,[$([*]C(F)(F)F)],* +1843,Naphthafurans,c1cccc2c1c3c(c5CNCOc25)cco3,C1NCc2c(c3ccccc3c3occc23)O1 +1844,Phenoxazines,"[OX1,N]=[#6]1-,:[#6]=,:[#6]2-,:[#16X2,#8X2]-,:[#6]3=,:[#6]-,:[#6](=,:[#6]-,:[#6]=,:[#6]3-,:[#7]=,:[#6]2-,:[#6]=,:[#6]1)",*=C1C=CC2=NC3=CC=CC=C3*C2=C1 +1845,Anthrones,"[#6]2=,:[#6]3-,:[#6]4=,:[#6](-,:[#6]=,:[#6]-,:[#6]=,:[#6]4)-,:[#6](=O)-,:[#6]4=,:[#6]3-,:[#6](=,:[#6]-,:[#6]=,:[#6]4)[#7]-,:[#6]2=O",O=C1C=C2C3=C(C=CC=C3)C(=O)C3=C2C(=CC=C3)N1 +1846,Imidazotriazoles,"[c,n]1cnn2c([NH])cnc12",[NH]c1cnc2*cnn12 +1847,Indenones,"[#6R1]1-,:[#6R1](=[OX1])c2ccccc2-,:[#6]([NX3])=,:1",NC1=CC(=O)c2ccccc21 +1848,Indolines,[CX4]1c2ccccc2[NX3]([CX4][CX4][CX4][NX3])[CX4]1,NCCCN1CCc2ccccc21 +1849,NCCN,"[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]-[$(c1[nv3X2][c,n][c,n,s][c,n]1),$(c2[nv3X2][c,n][c,n][c,n][c,n]2)]",** +1850,Picolylamines_A,"[$([NX3][CH2]c1ncnc([NX3])c1),$([NX3][CH2]c1nccc([NX3])n1)]",* +1851,Picolylamines_B,"[$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]n([H,CH3])cc1),$([NX3]([H,CX4!H0!R])([H,CX4!H0!R])[C!H0!R]c1[nv3X2]ccn1[H,CH3])]",* +1852,Picolylamines_C,"c1cccnc1[CH2!R][NX3!R]([H,CH3])[CH2!R]",*N([CH2])[CH2]c1ccccn1 +1853,Bis-picolylamines,"[nv3X2]c([c,s,n])[CX4][NX3]([H,C])[CX4]c([c,s,n])[nv3X2,nv3X3H1]",*N(Cc(*)*)Cc(*)n +1854,Alkylimidazoles_B,[nv3X2]1cncc1[CX4][CX4][NH2],[NH2]CCc1cncn1 +1855,Heterylimidazoles,[nv3X3]1c(-c[nv3X2])c[nv3X2]c1,nc-c1cncn1 +1856,Diarylamines,c([nv3X2])(c)[NX3H1!R]c([nv3X2])(c),cc(n)[NH]c(c)n +1857,Diarylmethanes,"[$(c1[nX2][c,n][c,n][c,n]1),$([cr6][nX2r6])][CX4H2!R][$(c2[nX2][c,n][c,n][c,n]2),$([cr6][nX2r6])]",*[CH2]* +1858,Heterylsulfides,"[SX2]-[#6R1]2=,:[#7R1]-,:[#6R1]=,:[#6R1]-,:[#7R2]3-,:[#6R1](=O)-,:[#7R1]-,:[#7R1]=,:[#6R2]23",O=C1NN=C2C(S)=NC=CN12 +1859,Heterylamides_A,"[$([cr5][n,s;r5][n,o;r5]),$([cr5]([nr5])[s,o,n;r5])][Nv3X3H1!R][CX3!R](=[OX1])[$([cr5][nv3X2r5]),$(c1ncccc1),$(c1c([OX2][CH3])cccc1)]",*[NH]C(*)=O +1860,Heterylamides_B,"[$(c1nnc[o,n]1),$(c1nccs1)][Nv3X3H!R][C!R](=[OX1])[CX4!H0]([H,CX4])[SX2,n]cc",*[NH]C(=O)C(*)*cc +1861,Pyrimidinetriones,C1=C([OH1])[NX3][CX3](=[OX1])[NX3][CX3]1(=[OX1]),O=C1C=C([OH])NC(=O)N1 +1862,8-Quinolinols,"[H,C][OX2]c1c([CX4][NX3])ccc2cccnc21",*Oc1c(CN)ccc2cccnc12 +1863,Benzoxozinones,c1cccc2[NX3][CX4][CX3](=[OX1])[OX2]c12,O=C1CNc2ccccc2O1 +1864,Perchloroquinone,"[OX1]=[CX3]1C([F,Cl,Br,I])=C([F,Cl,Br,I])[CX3](=[OX1])C([F,Cl,Br,I])=C1[F,Cl,Br,I]",*C1=C(*)C(=O)C(*)=C(*)C1=O +1865,Alkylimidazole_C,nc[nv3X3Hr5]c[CX4]c[nv3X2],ncCc[nH]cn +1866,"A1, A2, A4-A12, B2, B3, B4, B6",[OH][CX3](=[OX1])c1ncccc1,O=C([OH])c1ccccn1 +1867,A3,"[OH][CX3](=[OX1])[#6]1-,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:1",O=C([OH])C1=CC=CC=*1 +1868,B1,c1cccc2c1ccc([OH])n2,[OH]c1ccc2ccccc2n1 +1869,B5,"[#6]1=,:[#6]-,:[#6]=,:[#6]([OH])-,:[#6]2=,:[#6]1-,:[#6]=,:[#6]-,:[#6]=,:[$([#7X3+]-[OX1-]),$([#7v5X3]=[OX1])]2",[OH]C1=CC=CC2=C1*=CC=C2 +1870,"B7, B8, B9, B12",c1ccc([OH])c2c1cccn2,[OH]c1cccc2cccnc12 +1871,B10,c1ccc([SH])c2c1cccn2,[SH]c1cccc2cccnc12 +1872,B11,c1ccc([CX3](=[OX1])[OH])c2c1cccn2,O=C([OH])c1cccc2cccnc12 +1873,C2,[NH2]c1nc([NH2])cc([OH])n1,[NH2]c1cc([OH])nc([NH2])n1 +1874,"C3, C7, C8",[SH]c1nc([OH])ccn1,[OH]c1ccnc([SH])n1 +1875,C4,[OH]c1nc([SH])ccn1,[OH]c1nccc([SH])n1 +1876,C5,[SH]c1nc([CH3])cc([CH3])n1,[CH3]c1cc([CH3])nc([SH])n1 +1877,C5*,[SH]c1nc([CX4])cc([CX4])n1,Cc1cc(C)nc([SH])n1 +1878,"C6, C12",[OH]c1nc([OH])cc([CH3])n1,[CH3]c1cc([OH])nc([OH])n1 +1879,"C6*, C12*",[OH]c1nc([OH])cc([CX4])n1,Cc1cc([OH])nc([OH])n1 +1880,C9,[NH2]c1ncnc2c1nc[nH]2,[NH2]c1ncnc2[nH]cnc12 +1881,C9*,[NH2]c1ncnc2c1nc[nX3]2,[NH2]c1ncnc2ncnc12 +1882,"C10, C11","[CH3]c1nc([OH])cc([OH,CH3])n1",*c1cc([OH])nc([CH3])n1 +1883,"C10*, C11*","[CX4]c1nc([OH])cc([OH,CX4])n1",*c1cc([OH])nc(C)n1 +1884,"D1, D3, D4, D6-D11","O=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",O=C1C=COC=C1[OH] +1885,"D2, D5","S=[#6]1-,:[#6]([OH])=,:[#6]-,:[#8]-,:[#6]=,:[#6]-,:1",[OH]C1=COC=CC1=S +1886,D12,"O=[#6]1-,:[#8]-,:[#6]=,:[#6]-,:[#6]=,:[#6]([OH])-,:1",O=C1OC=CC=C1[OH] +1887,"E1, E10","O=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",O=C1C=CC=CN1[OH] +1888,E2,"S=[#6]1-,:[#7]([OH])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1",[OH]N1C=CC=CC1=S +1889,"E3*, E4*, E5*","O=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=O)C=CN1C +1890,"E6, E8","O=[#6]1-,:[#7]([H,CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",*N1C=CC=C([OH])C1=O +1891,"E6*, E8*","O=[#6]1-,:[#7X3]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",O=C1NC=CC=C1[OH] +1892,"E7*, E11*, E12*","S=[#6]1-,:[#6]([OH])=,:[#6]([CX4])-,:[#7]([CX4])-,:[#6]=,:[#6]-,:1",CC1=C([OH])C(=S)C=CN1C +1893,E9,"S=[#6]1-,:[#7]([CH3])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",[CH3]N1C=CC=C([OH])C1=S +1894,E9*,"S=[#6]1-,:[#7]([CX4])-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:1([OH])",CN1C=CC=C([OH])C1=S +1895,"F1, F3-F12",[OH]c1ccccc1[CX3](=[OX1])[OH],O=C([OH])c1ccccc1[OH] +1896,F2,[OH]c1ccccc1[CX3](=[OX1])[NH2],[NH2]C(=O)c1ccccc1[OH] +1897,G1,[CX4][CX3](=[OX1])[NX3H1][OH],CC(=O)[NH][OH] +1898,G1*,[CX4][CX3](=[OX1])[NX3][OH],CC(=O)N[OH] +1899,G2,[nX3H]1cccc1C(=[OX1])[OH],O=C([OH])c1ccc[nH]1 +1900,G2*,[nX3]1cccc1C(=[OX1])[OH],O=C([OH])c1cccn1 +1901,G3,c1ccnc(c1)C[NX3H]Cc2ccccn2,C([NH]Cc1ccccn1)c1ccccn1 +1902,G3*,c1ccnc(c1)C[NX3]Cc2ccccn2,C(NCc1ccccn1)c1ccccn1 +1903,G4,C1C[NX3H1]CC[NX3H1]CC[NX3H1]1,C1C[NH]CC[NH]CC[NH]1 +1904,G4*,C1C[NX3]CC[NX3]CC[NX3]1,C1CNCCNCCN1 +1905,G5,"c1ccc2c(c1)-,:[#6](=O)-,:[#6]=,:[#6](-,:[#6]2=O)[OH]",O=C1C=C([OH])C(=O)c2ccccc21 +1906,G6,c1cnc(cc1[CX4][OH])c2cc(ccn2)[CX4][OH],[OH]Cc1ccnc(c2cc(C[OH])ccn2)c1 +1907,G7,c1cc2c(nc1)c3c(cccn3)cc2,c1cnc2c(c1)ccc1cccnc12 +1908,G8,c1ccc(c(c1)[OH])[OH],[OH]c1ccccc1[OH] +1909,"G9,G10","c1ccc(c(c1)[OH,SH])[OX2][CX4]",*c1ccccc1OC +1910,"G11, G12","[OH][#6]1=,:[#6]-,:[#6]=,:[#6]-,:[#6]=,:[#6]-,:[#6]1=[OX1]",O=C1C=CC=CC=C1[OH] +1911,H1,c1ccc2c(c1)ccc(c2[OH])[OH],[OH]c1ccc2ccccc2c1[OH] +1912,H2,c1ccc2cc(c(cc2c1)[OH])[OH],[OH]c1cc2ccccc2cc1[OH] +1913,H3,c1cc(c(c(c1)[NH2])[OH])C(=[OX1])[OH],[NH2]c1cccc(C(=O)[OH])c1[OH] +1914,H4,c1cc(c(c(c1)[OH])[OH])C(=[OX1])[OH],O=C([OH])c1cccc([OH])c1[OH] +1915,H5,c1ccc(c(c1)c2nc3ccccc3o2)[OH],[OH]c1ccccc1c1nc2ccccc2o1 +1916,H6,c1ccc(c(c1)c2nc3ccccc3s2)[OH],[OH]c1ccccc1c1nc2ccccc2s1 +1917,H7,[CH3]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],[CH3]c1ccc(S([NH2])(=O)=O)cc1 +1918,H7*,[CX4]c1ccc(cc1)[Sv6X4](=[OX1])(=[OX1])[NX3H2],Cc1ccc(S([NH2])(=O)=O)cc1 +1919,H8 - H12,"C[CX3](=[OX1])[CX4!H0]([H,CX4,Cl])[CX3](=[OX1])C",*C(C(C)=O)C(C)=O +1920,H8*- H12*,C[CX3](=[OX1])[CX4][CX3](=[OX1])C,CC(=O)CC(C)=O +1921,Salts_C,"[!#1!#2!#5!#6!#7!#8!#9!#10!#14!#15!#16!#17!#18!#32!#33!#34!#35!#36!#51!#52!#53!#54!#84!#85!#86]~[#6,#7,#8,#16]",*~* +1922,Pt,[Pt],[Pt] +1923,N-methylol derivatives,[OX2;H1][CH2][NX3],N[CH2]O +1924,β-lactones and γ- sultones,"[$([OX2]1[CX4][CX4][CX3]1(=[OX1])),$([CX4]1[CX4][CX4][Sv6;X4](=[OX1])(=[OX1])[OX2]1)]",* +1925,"α,β unsaturated carbonyls",[CX3](=[OX1])[CX3H1]=[CX3],C=[CH]C=O +1926,Alkyl carbamate and thiocarbamate,"[NX3]([C,#1])([C,#1])[CX3](=[OX1,Sv2X1])[OX2,Sv2X2]C",*N(*)C(=*)*C +1927,Heterocyclic Polycyclic Aromatic Hydrocarbons,"[$([aR3].[n,o,s]),$([$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[$([aR2]([aR])([aR])([aR]))].[n,o,s])]",* +1928,Cyanothiopyrans,[NH2]C1=C(C#[NX1])[C!H0](-cc)C(C#[NX1])=C([NH2])S1,ccC1C(C#N)=C([NH2])SC([NH2])=C1C#N +1929,Cyanodithiine,"[#16X2]1-,:[#6X3]([CX2]#[NX1])=,:[#6X3]([CX2]#[NX1])-,:[#16X2]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]1([CX2]#[NX1])",N#CC1=C(C#N)SC(C#N)=C(C#N)S1 +1930,Azafluorenones,"[OX1,SX1]=[#6X3]1c2c([nX2][cX3,nX2,nX3][cX3,nX2,nX3][cX3,nX2,nX3]2)[c,n]2c1[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])]2",*=C1c2cccc*2c2n*:*:*c21 +1931,Cyanothioazinones,"[SX1]=[#6X3]1-,:[#7X3H1]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#7X2,#6X3!$([#6X3]=[A])]-,:[#7X2,#6X3!$([#6X3]=[A])]=,:[#6X3]1([CX2]#[NX1])",N#CC1=**=*[NH]C1=S +1932,Cyanopyridinones,"[OX1]=[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]([CX2]#[NX1])=,:[#6X3]2-,:[#7X3]([CX4][CX4]([OX2H1])[CX4][NX3H1]c5ccccc5)-,:[#6]3ccccc3-,:[#7X3]12",N#CC1=C2N(CC([OH])C[NH]c3ccccc3)C3ccccc3N2C(=O)C=C1 +1933,Thienopyridinones,[SX2]1C(=C(C4=C1[NX3!H0]C(C(=[C!H0]4)C(=[OX1])[OX2H1])=[OX1])[NX3H2])C(=[OX1])[NX3!H0],NC(=O)C1=C([NH2])C2=C(NC(=O)C(C(=O)[OH])=C2)S1 +1934,Pyranopyridinones,"[OX2]1[CX3]([NX3H2])=[CX3]([CX2]#[NX1])[CX4][#6X3]2[#6X3](=[OX1])-,:[#7X3H1]-,:[#6X3]=,:[#6X3]-,:[#6X3]12",N#CC1=C([NH2])OC2C=C[NH]C(=O)C2C1 +1935,Benzoxathiolones,"[$([#8]1-,:[#6](-,:[#16]c4cc(ccc14)[#7,#8])=[OX1,SX1]),$([#8]1-,:[#6](-,:[#16]c4ccc(cc14)[#7,#8])=[OX1,SX1])]",* +1936,Indoloquinones,"[#6X3]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]2-,:[#6X3]1-,:[#6X3](=[OX1])-,:[#6X3]3-,:[nX3]4-,:[#6X3](-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]4)=,:[#6X3]-,:[#6X3]3-,:[#6X3]2=[OX1]",O=C1C2CC=CC=C2C(=O)C2C=C3C=CC=Cn3C21 +1937,Pyrazolones,"[#7X2]1=,:[#6X3]-,:[#6X3](-,:[#6X3](-,:[#7X3]1)=[SX1,OX1])=,:[#6X3H1](-,:[#7X3H1])",*=C1NN=CC1=[CH][NH] +1938,Thiopyrylium,c1[#16+]cccc1,c1cccc[S+]1 +1939,Pyrimidinones_A,"[OX1,SX1]=[#6X3]1[#7X3](-,:[#7X2]=,:[#6X3][NX3H1][#6])-,:[cX3!$([#6X3]=[A])]=,:[#7X2]-,:[cX3!$([#6X3]=[A])]=,:[cX3!$([#6X3]=[A])]1",*=C1c=cN=cN1N=C[NH]C +1940,Pyrimidinones_B,"[OX1]=[#6X3]1-,:[#6X3]2scc-,:[#6X3]2-,:[#7X3]3-,:[#6X3](=,:[#7X2]-,:[#7X2]=,:[#6X3]3[CX4])-,:[#7X3]1[CX4H3]",CC1=NN=C2N([CH3])C(=O)C3sccC3N12 +1941,Pyrimidinones_C,"[OX1,SX1]=[#6X3]1[#7X3]-,:[#6X3!$([#6X3]=[A])](-[NX3])=,:[#7X2]-,:[#6X3]2([nX2][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])][#6X3!$([#6X3]=[A])]c12)",*=C1NC(N)=NC2nCCCc21 +1942,Pyrimidinodiones,"[#6X3]1(=[OX1,SX1])-,:[#7X3H1]-,:[#6X3](=[OX1,SX1])-,:[#7X3,#7X2]~[#6X3]([#7X2,#7X3;R1])-,:[#6X3]1[sX2r5R1,nX2r5R1,$([nx2r6R1]([cX3])[cX3])]",*C1C(*)C(=*)[NH]C(=*)*~1 +1943,Thienopyrimidinone_A,"[OX1,SX1]=[#6X3]1-,:[#7X3H1]-,:[#6X4]-,:[#7X3H1]-,:[#6]2-,:[#16X2,#8X2]-,:[#6]3[CX4][NX3,CX4][CX4][CX4]-,:[#6]3-,:[#6]12",*=C1[NH]C[NH]C2*C3C*CCC3C21 +1944,Piperazinediones,"[#7X3]1-,:[#6X3](=[OX1,SX1])-,:[#6X3](=[OX1,SX1])-,:[NX3]-,:[#6X3]2[cX3!$([#6X3]=[A])][cX3]([NX3H1][CX3]=[OX1])[cX3!$([#6X3]=[A])][cX3!$([#6X3]=[A])][cX3]12",*=C1NC2cc([NH]C=O)ccc2NC1=* +1945,4-Heteryl-thiazoles,"s1[c,nX2][c,nX2](-c(c)[nX2,nX3,sX2])[nX2]c1",*c(c)-*1:*scn1 +1946,Oxadiazoles,o1nc([CX4])nc1[CX4H2][SX4](=[OX1])(=[OX1])[CX4H2][CX3](=[OX1])[NX3!H0],Cc1noc([CH2]S(=O)(=O)[CH2]C(N)=O)n1 +1947,Cycloheptenones,"[#6]1-,:[#6]=,:[#6]-,:[#6X3](=[OX1])-,:[#6]([OX2H1])=,:[#6]-,:[#6]=,:1",O=C1C=CC=CC=C1[OH] +1948,Thiazoles,[nX2]1[cX3](-[cX3])[sX2][cX3][cX3]1[CX3](=[OX1])[NX3H2],c-c1nc(C([NH2])=O)cs1 +1949,Cyanothioethers,"[NX1]#[CX2][CX4H2][SX2]c1n[c,n][c,n][c,n]n1",N#C[CH2]Sc1n*:*:*n1 +1950,Aminopyrimidines_A,c1[nX2]c[nX2][nX3]1[CX4][CX4][NX3]([CX4])-c2cc[nX2]c(-c3cc[nX2]cc3)[nX2]2,CN(CCn1cncn1)c1ccnc(-c2ccncc2)n1 +1951,Fused azacycles_A,"[nX2R1][c,n;R2]1[c,n;R2]([c,n;R1])[c,n][c,n][c,n;R2]([c,n;R1])[nR2]1[nX2R1]",*:*1:*:*:*(:*)n(n)*:1n +1952,Fused azacycles_B,"[NX1]#[CX2]c1[c!$([#6]=[OX1])]n[n,c!$([#6]=[OX1])]2[c,n][c!$([#6]=[OX1])][c!$([#6]=[OX1])]nc12",N#Cc1cn*2:*ccnc21 +1953,Aminopyrimidines_B,[NX3H2]c1ncnc2ncccc21,[NH2]c1ncnc2ncccc12 +1954,Arylethanolamines,"[$([NX3]([CX4,H])([CX4,H])[CX4]),$([OX2]([H,CX4])[CX4])][CX4!H0][CX4H2][NX3H1]c[nX2r6R1][nX2,nX3][nX2,cX3;R1][cX3,nX2][cX3,nX2][sX2,cX3][cX3]",*C[CH2][NH]cn*:*:*:*:*c +1955,Azaspironones,"[X4;R2]12(-,:;@[#6X3]-,:;@[#6X3]-,:;@[#7X3]-,:;@[#6X3]-,:;@1)-,:;@[#16X2]-,:;@[#6X3]=,:;@[#7X2]-,:;@[#7X3]-,:;@2",C1C*2(CN1)NN=CS2 +1956,Radical,[#16;X3v3+0],S +1957,N⋯X halogen bonding,"N[F,Cl,Br,I]",*N +1958,Charged atoms,"[+,-]",* +1959,Benzyl Imidazole scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*-,=*c:3:c:c:c:c:c:3",*(*c1ccccc1)*1:*:*2:*c*c*:2:*:1 +1960,6-Phenyl Napthaline type scaffold,"[c,n]:1:c:[c,n]:[c,n]2:[c,n](:c:1)[c,n,o,s][c,n]([c,n,o,s][c,n,o,s]2)*~*c:3:c:c:c:c:c:3",*(~*c1ccccc1)*1:*:*:*2:*c*c*:2:*:1 +1961,2-(2-(1H-pyrrol-2-yl)ethyl)-1H-benzoimidazole scaffold,"[c,n]:1:c:c2:c(:[c,n]:c:1)[c,n,o,s][c,n]([c,n,o,s]2)*~*c3ccc*3",*(~*c1ccc*1)*1:*c2*c*cc2*:1 +1962,2 - Olefin group,"[$([CX3H2]=[CX3H1]),$([CX3H1]=[CX3H1]),$([CX3H2]=[CX3H0]),$([CX3H1]=[CX3H0]),$([CX3H0]=[CX3H0])]",* +1963,5 - Alcohol,[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +1964,6 - Methanol,[CX4H3][OX2H1],[CH3][OH] +1965,7 - Water,[OX2H2],O +1966,9 - Сarbonyl,"[$([CX4H3][CX3](=[OX1])[#6]),$([CX4H2][CX3H0](=[OX1])[#6])]",* +1967,10 - Aldehyde,[CX3H1]([#6])=[OX1],C[CH]=O +1968,11 - Acetate group,"[$([CX4H3][CX3](=[OX1])[OX2][#6]),$([CX4H2][CX3](=[OX1])[OX2][#6])]",* +1969,12 - Formate group,[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +1970,14 - Primary amine,"[$([CX4H3][NX3H2]),$([CX4H2][NX3H2]),$([CX4H1][NX3H2])]",* +1971,16 - Tertiary amine,"[$([CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]),$([CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6])]",* +1972,19 - CCN,"[$([CX4H3][CX2]#[NX1]),$([CX4H2][CX2]#[NX1])]",* +1973,20 - COOH,"[$([CX3H0](=[OX1])[OX2H1]),$([CX3H1](=[OX1])[OX2H1])]",* +1974,21 - CCl,"[$([CX4H2!$([CX4H2](Cl)Cl)]Cl),$([CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl]),$([CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl])]",* +1975,22 - CCl2,"[$([CX4H2]([Cl])[Cl]),$([CX4H1]([!Cl!F])([Cl])[Cl]),$([CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F])]",* +1976,23 - CCl3,"[$([CX4H1]([Cl])([Cl])[Cl]),$([CX4H0]([!Cl!F])([Cl])([Cl])[Cl])]",* +1977,24 - CCl4,[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +1978,26 - CNO2,"[$([CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]),$([CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)])]",* +1979,28 - Carbon disulphide,[SX1]=[CX2]=[SX1],S=C=S +1980,29 - CH3SH,"[$([CX4H3][SX2H1]),$([CX4H2][SX2H1])]",* +1981,30 - Furfural,"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +1982,31 - Ethanediol,[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +1983,32 - Iodo compounds,[I],I +1984,33 - Bromo compounds,[Br!$([Br][cR])],Br +1985,34 - Carbon triple bond,"[$([CX2H1]#[CX2H0]),$([CX2H0]#[CX2H0])]",* +1986,35 - Dimethylsulphoxide,[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +1987,36 - Acrylonitrile,[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +1988,"37 - Cl, double bonded carbon",[Cl][CX3]=[CX3],C=CCl +1989,39 - DMF,"[$([CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3]),$([CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2])]",* +1990,40 - CF2,"[$([CX4](F)(F)(F)[!Cl!F]),$([CX4](F)(F)([!F!Cl!H])([!F!Cl!H])),$([CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]))]",* +1991,41 - Acrylate,[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +1992,42 - SiH2,"[$([SiX4H3]),$([SiX4H2]([!$([OX2])])([!$([OX2])])),$([SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])])),$([SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]))]",* +1993,43 - SiO,"[$([SiX4H2][OX2]),$([SiX4H1][OX2]),$([SiX4H0][OX2])]",* +1994,44 - Methylpyrrolidone,[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +1995,47 - OCCOH,"[$([OX2H0!R][CX4H2][CX4H2][OX2H1]),$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +1996,49 - Morpholine,[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +1997,52 - Sulphones,"[$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2]),$([CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1])]",* +1998,53 - Oxides,"[$([CX4H2]1[OX2][CX4H2]1),$([CX4H2]1[OX2][CX4H1]1),$([CX4H2]1[OX2][CX4H0]1),$([CX4H1]1[OX2][CX4H1]1),$([CX4H1]1[OX2][CX4H0]1),$([CX4H0]1[OX2][CX4H0]1)]",* +1999,54 - Anhydrides,[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2000,5 - CH2=CH (2 - Olefin group),[CX3H2]=[CX3H1],[CH]=C +2001,6 - CH=CH (2 - Olefin group),[CX3H1]=[CX3H1],[CH]=[CH] +2002,7 - CH2=C (2 - Olefin group),[CX3H2]=[CX3H0],C=C +2003,8 - CH=C (2 - Olefin group),[CX3H1]=[CX3H0],[CH]=C +2004,9 - C=C (2 - Olefin group),[CX3H0]=[CX3H0],C=C +2005,14 - ACCH (4 - Aromatic carbon-alkane),[cR]-[CX4H1],[CH]c +2006,15 - OH (5 - Alcohol),[OX2H1!$([OX2H1][CX4H3])!$([OX2H1]-c)!$([OX2H1][CX3]=[OX1])!$([OX2H1][CX4H2][CX4H2][OX2H1])!$([OX2H1][CX4H2][CX4H2][OX2H0!R])!$([OX2H1][CX4H2][CX4H1][OX2H0!R])!$([OX2H1][CX4H1][CX4H2][OX2H0!R])],[OH] +2007,16 - CH3OH (6 - Metanol),[CX4H3][OX2H1],[CH3][OH] +2008,17 - H2O (7 - Water),[OX2H2],O +2009,19 - CH3CO (9 - Сarbonyl),[CX4H3][CX3](=[OX1])[#6],CC([CH3])=O +2010,20 - CH2CO (9 - Сarbonyl),[CX4H2][CX3H0](=[OX1])[#6],CC([CH2])=O +2011,21 - CHO (10 - Aldehyde),[CX3H1]([#6])=[OX1],C[CH]=O +2012,22 - CH3COO (11 - Acetate group),[CX4H3][CX3](=[OX1])[OX2][#6],COC([CH3])=O +2013,23 - CH2COO (11 - Acetate group),[CX4H2][CX3](=[OX1])[OX2][#6],COC([CH2])=O +2014,24 - HCOO (12 - Formate group),[CX3H1](=[OX1])[OX2][#6],CO[CH]=O +2015,25 - CH3O (13 - Ether),"[CX4H3][OX2!R!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2][CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])][#6]",CO[CH3] +2016,26 - CH2O (13 - Ether),"[CX4H2][OX2!R!$([OX2][CX4H2][CX4H2][OX2H1])!$([OX2]([CX4H2])[CX4H1][CX4H2][OX2H1])!$([OX2][CX4H2][CX4H1][OX2H1])!$([OX2][CX3]=[OX1,SX1,NX2])!$([OX2]([CX4H2])[CX4H3])][#6]",CO[CH2] +2017,28 - THF (13 - Ether),[OX2R!r3!$([OX2]C=[OX1])!$([OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1)]([R])[CX4H2R],*O[CH2] +2018,29 - CH3NH2 (14 - Primary amine),[CX4H3][NX3H2],[CH3][NH2] +2019,30 - CH2NH2 (14 - Primary amine),[CX4H2][NX3H2],[CH2][NH2] +2020,31 - CHNH2 (14 - Primary amine),[CX4H1][NX3H2],[CH][NH2] +2021,32 - CH3NH (15 - Secondary amine group),[CX4H3][NX3H1!$([NX3H1]([CX4H3])[CX3]=[OX1])][#6],C[NH][CH3] +2022,33 - CH2NH (15 - Secondary amine group),[CX4H2][NX3H1!$([NX3H1]1[CX4H2][CX4H2][OX2][CX4H2][CX4H2]1)!$([NX3H1]([CX4H2])[CX3]=[OX1])!$([NX3H1]([CX4H3])[CX4H2])][#6],C[NH][CH2] +2023,34 - CHNH (15 - Secondary amine group),[CX4H1][NX3H1!$([NX3H1][CX4H3])!$([NX3H1][CX4H2])][#6],C[NH][CH] +2024,35 - CH3N (16 - Tertiary amine),"[CX4H3][NX3!$([NX3]([CX4H3])([CH3,CH2])[CX3]=[OX1])]([#6])[#6]",CN(C)[CH3] +2025,36 - CH2N (16 - Tertiary amine),"[CX4H2][NX3!$([NX3]([CX4H2])([CH3,CH2])[CX3]=[OX1])!$([NX3][CX4H3])]([#6])[#6]",CN(C)[CH2] +2026,38 - C5H5N (18 - Pyridine),[cH1]1[nX2][cH1][cH1][cH1][cH1]1,[cH]1[cH][cH]n[cH][cH]1 +2027,39 - C5H4N (18 - Pyridine),"[$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]1),$([nX2]1:[cX3H1]:[cX3H1]:[cX3H0]:[cX3H1]:[cX3H1]1)]",* +2028,41 - CH3CN (19 - CCN),[CX4H3][CX2]#[NX1],[CH3]C#N +2029,42 - CH2CN (19 - CCN),[CX4H2][CX2]#[NX1],[CH2]C#N +2030,43 - COOH (20 - COOH),[CX3H0](=[OX1])[OX2H1],O=C[OH] +2031,44 - HCOOH (20 - COOH),[CX3H1](=[OX1])[OX2H1],O=[CH][OH] +2032,45 - CH2Cl (21 - CCl),[CX4H2!$([CX4H2](Cl)Cl)]Cl,[CH2]Cl +2033,46 - CHCl (21 - CCl),[CX4H1!$([CX4H1]([Cl])F)!$([CX4H1]([Cl])(F)F)]([!Cl])([!Cl])[Cl],*[CH](*)Cl +2034,47 - CCl (21 - CCl),[CX4H0]([!Cl!F])([!Cl!F])([!Cl!F])[Cl],*C(*)(*)Cl +2035,48 - CH2Cl2 (22 - CCl2),[CX4H2]([Cl])[Cl],Cl[CH2]Cl +2036,49 - CHCl2 (22 - CCl2),[CX4H1]([!Cl!F])([Cl])[Cl],*[CH](Cl)Cl +2037,50 - CCl2 (22 - CCl2),[CX4H0]([Cl])([Cl])([!Cl!F])[!Cl!F],*C(*)(Cl)Cl +2038,51 - CHCl3 (23 - CCl3),[CX4H1]([Cl])([Cl])[Cl],Cl[CH](Cl)Cl +2039,52 - CCl3 (23 - CCl3),[CX4H0]([!Cl!F])([Cl])([Cl])[Cl],*C(Cl)(Cl)Cl +2040,53 - CCl4 (24 - CCl4),[CX4]([Cl])([Cl])([Cl])[Cl],ClC(Cl)(Cl)Cl +2041,55 - CH3NO2 (26 - CNO2),"[CX4H3][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH3] +2042,56 - CH2NO2 (26 - CNO2),"[CX4H2][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH2] +2043,57 - CHNO2 (26 - CNO2),"[CX4H1][$([NX3+](=[OX1])([O-])),$([NX3](=O)=O)]",*[CH] +2044,59 - CS2 (28 - Carbon disulphide),[SX1]=[CX2]=[SX1],S=C=S +2045,60 - CH3SH (29 - CH3SH),[CX4H3][SX2H1],[CH3][SH] +2046,61 - CH2SH (29 - CH3SH),[CX4H2][SX2H1],[CH2][SH] +2047,62 - Furfural (30 - Furfural ),"[OX2]1-,:[#6X3]=,:[#6X3]-,:[#6X3]=,:[#6X3]([CX3H1]=[OX1])-,:1",O=[CH]C1=CC=CO1 +2048,63 - DOH (31 - Ethanediol),[OX2H1][CX4H2][CX4H2][OX2H1],[OH][CH2][CH2][OH] +2049,64 - I (32 - Iodo compounds),[I],I +2050,65 - Br (33 - Bromo compounds),[Br!$([Br][cR])],Br +2051,66 - CH#C (34 - Carbon triple bond),[CX2H1]#[CX2H0],C#C +2052,67 - C#C (34 - Carbon triple bond),[CX2H0]#[CX2H0],C#C +2053,68 - DMSO (35 - Dimethylsulphoxide),[CX4H3][Sv4X3](=[OX1])[CX4H3],[CH3]S([CH3])=O +2054,69 - ACRY (36 - Acrylonitrile),[CX3H2]=[CX3H1][CX2]#[NX1],C=[CH]C#N +2055,"70 - Cl-C=C (37 - Cl, double bonded carbon )",[Cl][CX3]=[CX3],C=CCl +2056,72 - DMF (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])[CH]=O +2057,73 - HCON(CH2)2 (39 - Dimethylformamide),[CX3H1](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])[CH]=O +2058,74 - CF3 (40 - CF2),[CX4](F)(F)(F)[!Cl!F],*C(F)(F)F +2059,75 - CF2 (40 - CF2),[CX4](F)(F)([!F!Cl!H])([!F!Cl!H]),*C(*)(F)F +2060,76 - CF (40 - CF2),[CX4](F)([!F!Cl!H])([!F!Cl!H])([!F!Cl!H]),*C(*)(*)F +2061,77 - COO (41 - Acrylate),[#6!$([CX4H3])!$([CX4H2])][CX3](=[OX1])[OX2][#6],COC(C)=O +2062,78 - SiH3 (42 - SiH2),[SiX4H3],[SiH3] +2063,79 - SiH2 (42 - SiH2),[SiX4H2]([!$([OX2])])([!$([OX2])]),*[SiH2]* +2064,80 - SiH (42 - SiH2),[SiX4H1]([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[SiH](*)* +2065,81 - Si (42 - SiH2),[SiX4H0]([!$([OX2])])([!$([OX2])])([!$([OX2])])([!$([OX2])]),*[Si](*)(*)* +2066,82 - SiH2O (43 - SiO),[SiX4H2][OX2],O[SiH2] +2067,83 - SiHO (43 - SiO),[SiX4H1][OX2],O[SiH] +2068,84 - SiO (43 - SiO),[SiX4H0][OX2],O[Si] +2069,85 - NMP (44 - Methylpyrrolidone),[CX4H2]1[NX3]([CX4H3])[CX3](=[OX1])[CX4H2][CX4H2]1,[CH3]N1[CH2][CH2][CH2]C1=O +2070,86 - CCl3F (45 - CClF),[CX4]([Cl])([Cl])([Cl])[F],FC(Cl)(Cl)Cl +2071,87 - CCl2F (45 - CClF),[CX4H0]([Cl])([Cl])([F])[!Cl!F],*C(F)(Cl)Cl +2072,88 - HCCl2F (45 - CClF),[CX4H1]([Cl])([Cl])F,F[CH](Cl)Cl +2073,89 - HCClF (45 - CClF),[CX4H1](Cl)(F)([!F!Cl]),*[CH](F)Cl +2074,90 - CClF2 (45 - CClF),[CX4H0](Cl)(F)(F)[!Cl!F],*C(F)(F)Cl +2075,91 - HCClF2 (45 - CClF),[CX4H1](Cl)(F)F,F[CH](F)Cl +2076,92 - CClF3 (45 - CClF),[CX4](Cl)(F)(F)F,FC(F)(F)Cl +2077,93 - CCl2F2 (45 - CClF),[CX4](Cl)(Cl)(F)F,FC(F)(Cl)Cl +2078,94 - CONH2 (46 - CON),[CX3](=[OX1])[NX3H2],[NH2]C=O +2079,95 - CONHCH3 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H3],[CH3][NH]C=O +2080,96 - CONHCH2 (46 - CON),[CX3](=[OX1])[NX3H1][CX4H2],[CH2][NH]C=O +2081,97 - CON(CH3)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H3],[CH3]N([CH3])C=O +2082,98 - CONCH3CH2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H3])[CX4H2],[CH2]N([CH3])C=O +2083,99 - CON(CH2)2 (46 - CON),[CX3](=[OX1])[NX3]([CX4H2])[CX4H2],[CH2]N([CH2])C=O +2084,100 - C2H5O2 (47 - OCCOH),[OX2H0!R][CX4H2][CX4H2][OX2H1],O[CH2][CH2][OH] +2085,101 - C2H4O2 (47 - OCCOH),"[$([OX2H0!R][CX4H1][CX4H2][OX2H1]),$([OX2H0!R][CX4H2][CX4H1][OX2H1])]",* +2086,102 - CH3S (48 - CH2S),[CX4H3][SX2H0][*],*S[CH3] +2087,103 - CH2S (48 - CH2S),[CX4H2][SX2H0!$([SX2H0]([CX4H2])[CX4H3])][*],*S[CH2] +2088,105 - MORPH (49 - Morpholine),[OX2]1[CX4H2][CX4H2][NX3H1][CX4H2][CX4H2]1,[CH2]1[CH2]O[CH2][CH2][NH]1 +2089,106 - C4H4S (50 - Thiophene),"[#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H1]=,:1",[CH]1=[CH]S[CH]=[CH]1 +2090,107 - C4H3S (50 - Thiophene),"[$([#6X3H1]1-,:[#16X2]-,:[#6X3H1]=,:[#6X3H1]-,:[#6X3H0]=,:1),$([#6X3H1]1-,:[#16X2]-,:[#6X3H0]=,:[#6X3H1]-,:[#6X3H1]=,:1)]",* +2091,109 - NCO (51 - NCO),[*][NX2]=[CX2]=[OX1],*N=C=O +2092,110 - CH2SuCH2 (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H2],[CH2]S([CH2])(=O)=O +2093,111 - CH2SuCH (52 - Sulphones),[CX4H2][Sv6X4](=[OX1])(=[OX1])[CX4H1],[CH]S([CH2])(=O)=O +2094,112 - CH2OCH2 (53 - Oxides),[CX4H2]1[OX2][CX4H2]1,[CH2]1[CH2]O1 +2095,113 - CH2OCH (53 - Oxides),[CX4H2]1[OX2][CX4H1]1,[CH]1[CH2]O1 +2096,114 - CH2OC (53 - Oxides),[CX4H2]1[OX2][CX4H0]1,C1[CH2]O1 +2097,115 - CHOCH (53 - Oxides),[CX4H1]1[OX2][CX4H1]1,[CH]1[CH]O1 +2098,116 - CHOC (53 - Oxides),[CX4H1]1[OX2][CX4H0]1,C1[CH]O1 +2099,117 - COC (53 - Oxides),[CX4H0]1[OX2][CX4H0]1,C1CO1 +2100,118 - O=COC=O (54 - Anhydrides),[CX3](=[OX1])[OX2][CX3](=[OX1]),O=COC=O +2101,phosphorodithionate,[$([SX2H0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2102,"O,O-diethylphosphorodithionate",CCOP(=S)(OCC)SC([*:1]),CCOP(=S)(OCC)SC[*:1] +2103,phosphoryl,[PX4H0](=O)([OH0])([OH0])[OH0],OP(O)(O)=O +2104,"O,O-dimethylphosphoryl",COP(=O)(O([*:1]))OC,COP(=O)(OC)O[*:1] +2105,phosphorothionate,[$([OH0]P(=S)([OH0])[OH0])]P(=S)([OH0])[OH0],*P(O)(O)=S +2106,diethylphosphorothionate,CCOP(=S)(O([*:1]))OCC,CCOP(=S)(OCC)O[*:1] +2107,O-phenyl phenylphosphonothioate,S=P(O([*:1]))(Oc1ccc([*:1])cc1)c1ccccc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])c1ccccc1 +2108,O-phenyl phosphonothioate,S=P(O([*:1]))(O([*:1]))Oc1ccc([*:1])cc1,S=P(Oc1ccc([*:1])cc1)(O[*:1])O[*:1] +2109,carbamate,[$(N([!H])C(=O)[OH0])]C(=O)[OH0],*C(O)=O +2110,"2,2-dimethyl-2,3-dihydro-1-benzofuran-7-yl N-(aminosulfanyl)-N-methylcarbamate",CN(SN([*:1])([*:1]))C(=O)Oc1cccc2CC(C)(C)Oc12,CN(SN([*:1])[*:1])C(=O)Oc1cccc2c1OC(C)(C)C2 +2111,methyl(propoxysulfanyl) carbamate,CN(SOCCC([*:1]))C(=O)O([*:1]),CN(SOCCC[*:1])C(=O)O[*:1] +2112,phenyl carbamate,O=C(N([*:1]))Oc1ccccc([*:1])1,O=C(N[*:1])Oc1ccccc1[*:1] +2113,O-(methylaminocarbonyl)oxime,[CX4]NC(=O)ON=C,CNC(=O)ON=C +2114,dimethylcarbamate,CN(C)C(=O)O([*:1]),CN(C)C(=O)O[*:1] +2115,barbiturates,*C1(*)[#6](=O)-[#7]-[#6](=O)-[#7]-[#6]1=O,*C1(*)C(=O)NC(=O)NC1=O +2116,4-Hydroxycoumarin,[OH1]C1=CC(=O)Oc2[cH][cH][cH][cH]c12,O=C1C=C([OH])c2[cH][cH][cH][cH]c2O1 +2117,Phenothiazine,*-[#7]-1-c2ccccc2-[#16]-c2ccccc-12,*N1c2ccccc2Sc2ccccc21 +2118,1-carboximidoylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1]([CX3]=[NX2])[CX4R1][CX4R1]1,N=CN1CCNCC1 +2119,phenylpiperazine,[NR1X3]1[CX4R1][CX4R1][NX3R1](c2ccccc2)[CX4R1][CX4R1]1,C1CN(c2ccccc2)CCN1 +2120,"2,4-dichloro-benzene-1,3-dicarbonitrile",N#Cc1c([*:1])c([*:1])c(Cl)c(C#N)c1Cl,N#Cc1c(Cl)c(C#N)c([*:1])c([*:1])c1Cl +2121,R1 - Reactive alkyl halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2122,R2 - Acid halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2123,R3 - Carbazides,O=CN=[N+]=[N-],[N-]=[N+]=NC=O +2124,R4 - Sulphate esters,"COS(=O)O[C,c]",*OS(=O)OC +2125,R5 - Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2126,R6 - Acid anhydrides,C(=O)OC(=O),O=COC=O +2127,R7 - Peroxides,OO,OO +2128,R8 - Pentafluorophenyl esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2129,R9 - Paranitrophenyl esters,C(=O)Oc1ccc(N(=O)=O)cc1,O=COc1ccc(N(=O)=O)cc1 +2130,R10 - Esters of HOBT (Hydroxybenzotriazole),C(=O)Onnn,nnnOC=O +2131,R11 - Isocyanates & Isothiocyanantes,"N=C=[S,O]",*=C=N +2132,R12 - Triflates,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2133,R13 - Lawesson's reagent and derivatives,P(=S)(S)S,SP(S)=S +2134,R14 - Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2135,R15 - Aromatic azides,cN=[N+]=[N-],cN=[N+]=[N-] +2136,R16 - beta carbonyl quaternary Nitrogen,"C(=O)C[N+,n+]",*CC=O +2137,R17 - Acylhydrazide,[N;R0][N;R0]C(=O),NNC=O +2138,"R18 - Quaternary C,Cl,I,P or S","[C+,Cl+,I+,P+,S+]",* +2139,R19 - Phosphoranes,C=P,C=P +2140,R20 - Chloramidines,[Cl]C([C&R0])=N,CC(=N)Cl +2141,R21 - Nitroso,[N&D2](=O),N=O +2142,R22 - P/S Halides,"[P,S][Cl,Br,F,I]",** +2143,R23 - Carbodiumide,N=C=N,N=C=N +2144,R24 - Isonitrile,[N+]#[C-],[C-]#[NH+] +2145,R25 - Triacyloximes,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2146,R26 - Cyanohydrins,N#CC[OH],N#CC[OH] +2147,R27 - Acyl cyanides,N#CC(=O),N#CC=O +2148,R28 - Sulfonyl cyanides,S(=O)(=O)C#N,N#CS(=O)=O +2149,R29 - Cyanophosphonates,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2150,R30 - Azocyanamides,[N;R0]=[N;R0]C#N,N#CN=N +2151,R31 - Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2152,I1 - Aliphatic methylene chains 7 or more long,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCCC +2153,I2 - Compounds with 4 or more acidic groups,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2154,I3 - Crown ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2155,I4 - Disulphides,SS,SS +2156,I5 - Thiols,[SH],[SH] +2157,"I6 - Epoxides, Thioepoxides, Aziridines","C1[O,S,N]C1",*1CC1 +2158,"I7 - 2,4,5 trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2159,"I8 - 2,3,4 trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2160,I9 - Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2161,I10 - Thiocyanate,SC#N,N#CS +2162,I11 - Benzylic quaternary Nitrogen,cC[N+],cC[N+] +2163,I12 - Thioesters,"C[O,S;R0][C;R0](=S)",C*C=S +2164,I13 - Cyanamides,N[CH2]C#N,N[CH2]C#N +2165,I14 - Four membered lactones,C1(=O)OCC1,O=C1CCO1 +2166,I15 - Di and Triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2167,I16 - Betalactams,N1CCC1=O,O=C1CCN1 +2168,N1 - Quinones,O=C1[#6]~[#6]C(=O)[#6]~[#6]1,O=C1C~CC(=O)C~C1 +2169,N2 - Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2170,N3 - Saponin derivatives,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2171,N4 - Cytochalasin derivatives,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2172,N5 - Cycloheximide derivatives,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2173,N6 - Monensin derivatives,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2174,N7 - Cyanidin derivatives,[OH]c1cc([OH])cc2[O+]=C(C([OH])=Cc21)c3cc([OH])c([OH])cc3,[OH]C1=Cc2c([OH])cc([OH])cc2[O+]=C1c1ccc([OH])c([OH])c1 +2175,N8 - Squalestatin derivatives,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2176,"A1 - e.g., carboxylic acid","[OH1][P,C,S](=O)",O=*[OH] +2177,"A2 - e.g.,imide","[NH1]([P,S]=O)([P,S]=O)",O=*[NH]*=O +2178,A4,[OH1]C1=NC=NO1,[OH]C1=NC=NO1 +2179,A5,[NH1]1C=NOS1=O,O=S1[NH]C=NO1 +2180,A6,[OH1]C1=NC(=O)CC1=O,O=C1CC(=O)C([OH])=N1 +2181,A7,[OH1]C1NC(=O)C(=O)C1,O=C1CC([OH])NC1=O +2182,A8,[nH1]1ncoc1=O,O=c1[nH]nco1 +2183,A9,[OH1]C1=NN=CO1,[OH]C1=NN=CO1 +2184,A10,[nH1]1[nH]cnc1=O,O=c1nc[nH][nH]1 +2185,A11,[OH1]C1=N[NH1]C=N1,[OH]C1=N[NH]C=N1 +2186,A12,[OH1]C1=NOC=C1,[OH]C1=NOC=C1 +2187,A13,[nH1]1occc1=O,O=c1cco[nH]1 +2188,A14,[OH1]c1oncc1,[OH]c1ccno1 +2189,A15,[nH1]1ccc(=O)o1,O=c1cc[nH]o1 +2190,A16 - tetrazole,[nH1]nnn,nnn[nH] +2191,A17,[nH1](n)nn,nn[nH]n +2192,A18,[OH1]C1=NC(=O)NO1,O=C1NOC([OH])=N1 +2193,A19,[OH1]C1=NC(=O)ON1,O=C1N=C([OH])NO1 +2194,A20,[nH1]1cnnc1C(F)(F)F,FC(F)(F)c1nnc[nH]1 +2195,A21,[nH1]1cnc(n1)C(F)(F)F,FC(F)(F)c1nc[nH]n1 +2196,A22,[nH1]1C(=O)CC(=O)O1,O=C1CC(=O)O[nH]1 +2197,A23,[OH1]C1=CC(=O)NO1,O=C1C=C([OH])ON1 +2198,A24,[OH1]C1=CC(=O)ON1,O=C1C=C([OH])NO1 +2199,A25 - benzosulphimide,[NH1]1C(=O)c2ccccc2S1(=O)=O,O=C1[NH]S(=O)(=O)c2ccccc21 +2200,A26,[OH1]C1=NS(=O)(=O)c2ccccc21,O=S1(=O)N=C([OH])c2ccccc21 +2201,A27,[OH1]C1=NC(=O)c2ccccc21,O=C1N=C([OH])c2ccccc21 +2202,A28,[OH1]C1=COC=CC1=O,O=C1C=COC=C1[OH] +2203,A29,[OH1]C1=NSN=C1,[OH]C1=NSN=C1 +2204,A30 - hyroxamic acid,[OH1]NC(=O),O=CN[OH] +2205,A31 - trifluoromethyl sulphonamide,[NH]S(=O)(=O)C(F)(F)F,[NH]S(=O)(=O)C(F)(F)F +2206,A32 - aryl sulphonamide,[NH](c)S(=O)=O,c[NH]S(=O)=O +2207,A33 - phenol,"[OH1]c1c[c,n]ccc1",[OH]c1c*ccc1 +2208,B1 - primary amine,[NH2][CX4],C[NH2] +2209,B2 - secondary amine,[NH]([CX4])[CX4],C[NH]C +2210,B3 - tertiary amine,[NX3]([CX4])([CX4])[CX4],CN(C)C +2211,B4SUB,"[C,c](=N)N",N*=N +2212,B5EXC,"[C,c](=N)N[C,S](=O)",N=*N*=O +2213,B6,"[$([C,c](=N)N);!$([C,c](=N)N[C,S](=O))]",* +2214,B7EXC,n(:c)(:c):a,*n(c)c +2215,B7,[nH0;!$(n-C);!$(n(:c)(:c):a)]1ccccc1,c1ccncc1 +2216,B8EXC,"[N,n;+1]",* +2217,B9,"[$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]",* +2218,E1 - alkyl and aryl ketones and aldehydes,"[C;H1](=[O,S])[C,c]",*C=* +2219,"E2 - e.g., carboxylic esters","[C,P;H1](=[O,S])[O,S]",**=* +2220,"E3 - e.g., carbonates","[C](=O)([C,c,O,S])[C,c,O,S]",*C(*)=O +2221,E4EXC,C(=O)[OH1],O=C[OH] +2222,E5EXC,C(=O)[SH1],O=C[SH] +2223,E6,"C(=[O,S])(N)Oc",*=C(N)Oc +2224,"E7 - e.g., aryl carbamates","C1(=O)NS(=O)(=O)[C,c]=,:[C,c]1",O=C1*=*S(=O)(=O)N1 +2225,E8SUB,"P(=O)[O,S]",*P=O +2226,E9EXC,P[OH1],[OH]P +2227,E10,"[$(P(=O)[O,S]);!$(P[OH1])]",* +2228,E11,c(=O)(~c)~c,c~c(~c)=O +2229,E12EXC,"[$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)]",* +2230,E12,"[$(c(=O)(~c)~c);!$([$(c1(=O)ccn([C,c])cc1),$(c1(=O)n([C,c])cccc1)])]",* +2231,E13 - imides,C(=O)-N-C=O,O=CNC=O +2232,N1 - pimary amines,[NX3H2][CX4],C[NH2] +2233,N2 - secondary amines,[NX3H]([CX4])[CX4],C[NH]C +2234,N4EXC,"N=[O,C,N,S]",*=N +2235,N5EXC,"N-[C,c,N]=[C,c,N,n,O,S]",*=*N +2236,N6,"[OH1][C,c,N;!$(C=O)]",*[OH] +2237,N7EXC,[OH1]C=C,C=C[OH] +2238,N8EXC,"[OH1]NC=[O,S]",*=CN[OH] +2239,N9,"[$([NX3H2]!:c),$([NX3H1]([CX4])!:c),$([NX3H0]([CX4])([CX4])!:c)]",* +2240,NUC,"[$([NH2][CX4]),$([NH]([CX4])[CX4]),$([OH1][C,c,N;!$(C=O)]),$([$([NH2]!:c),$([NH1]([CX4])!:c),$([NH0]([CX4])([CX4])!:c)]);!$(N=[O,C,N,S]);!$(N-[C,c,N]=[C,c,N,n,O,S]);!$([OH1]C=C);!$([OH1]NC=[O,S])]",* +2241,> 2 ester groups,"C(=O)O[C,H1].C(=O)O[C,H1].C(=O)O[C,H1]",*OC=O.*OC=O.*OC=O +2242,2-halo pyridine,"n1c([F,Cl,Br,I])cccc1",*c1ccccn1 +2243,Acid halide,"C(=O)[Cl,Br,I,F]",*C=O +2244,Acyclic C=C-O,C=[C!r]O,C=CO +2245,Acyl cyanide,N#CC(=O),N#CC=O +2246,Acyl hydrazine,C(=O)N[NH2],[NH2]NC=O +2247,Aliphatic long chain,[R0;D2][R0;D2][R0;D2][R0;D2],**** +2248,Aniline,c1cc([NH2])ccc1,[NH2]c1ccccc1 +2249,Azepane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2]1 +2250,Azido group,N=[N+]=[N-],[N-]=[N+]=N +2251,Azo group,N=N,N=N +2252,Azocane,[CH2R1]1N[CH2R1][CH2R1][CH2R1][CH2R1][CH2R1][CH2R1]1,[CH2]1[CH2][CH2][CH2]N[CH2][CH2][CH2]1 +2253,Benzidine,"[cR2]1[cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2][cR2]1[cR2]2[cR2][cR2][cR2]([Nv3X3,Nv4X4])[cR2][cR2]2",*c1ccc(c2ccc(*)cc2)cc1 +2254,Betaketo/anhydride,"[C,c](=O)[CX4,CR0X3,O][C,c](=O)",O=***=O +2255,Biotin analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2256,Carbo cation/anion,"[C+,c+,C-,c-]",* +2257,Catechol,"c1c([OH])c([OH,NH2,NH])ccc1",*c1ccccc1[OH] +2258,Charged oxygen or sulfur atoms,"[O+,o+,S+,s+]",* +2259,Chinone (1),"C1(=[O,N])C=CC(=[O,N])C=C1",*=C1C=CC(=*)C=C1 +2260,Chinone (2),"C1(=[O,N])C(=[O,N])C=CC=C1",*=C1C=CC=CC1=* +2261,Conjugated nitrile group,C=[C!r]C#N,C=CC#N +2262,Crown ether,"[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]@[CR2]@[CR2]@[OR2,NR2]",*~C~C~*~C~C~* +2263,Cumarine,c1ccc2c(c1)ccc(=O)o2,O=c1ccc2ccccc2o1 +2264,Cyanamide,N[CH2]C#N,N[CH2]C#N +2265,Cyanate/aminonitrile/thiocyanate,"[N,O,S]C#N",*C#N +2266,Cyanohydrins,N#CC[OH],N#CC[OH] +2267,Cycloheptane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCC1 +2268,Cycloheptane (2),[CR1]1[CR1][CR1]cc[CR1][CR1]1,C1CCccCC1 +2269,Cyclooctane (1),[CR1]1[CR1][CR1][CR1][CR1][CR1][CR1][CR1]1,C1CCCCCCC1 +2270,Cyclooctane,[CR1]1[CR1][CR1]cc[CR1][CR1][CR1]1,C1CCCccCC1 +2271,Diaminobenzene (1),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])c([N+R0,NX3R0,nX3R0])[cR2][cR2]1",*c1ccccc1* +2272,Diaminobenzene (2),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2]c([N+R0,NX3R0,nX3R0])[cR2]1",*c1cccc(*)c1 +2273,Diaminobenzene (3),"[cR2]1[cR2]c([N+R0,NX3R0,nX3R0])[cR2][cR2]c1([N+R0,NX3R0,nX3R0])",*c1ccc(*)cc1 +2274,Diazo group,[N!R]=[N!R],N=N +2275,Diketo group,"[C,c](=O)[C,c](=O)",O=**=O +2276,Disulphide,SS,SS +2277,Enamine,[CX3R0][NX3R0],CN +2278,Ester of HOBT,C(=O)Onnn,nnnOC=O +2279,Four member lactones,C1(=O)OCC1,O=C1CCO1 +2280,Halogenated ring (1),"c1cc([Cl,Br,I,F])cc([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1ccc(*)c(*)c1 +2281,Halogenated ring (2),"c1ccc([Cl,Br,I,F])c([Cl,Br,I,F])c1[Cl,Br,I,F]",*c1cccc(*)c1* +2282,Heavy metal,"[Hg,Fe,As,Sb,Zn,Se,se,Te,B,Si]",* +2283,Het-c-het not in ring,"[NX3R0,NX4R0,OR0,SX2R0][CX4][NX3R0,NX4R0,OR0,SX2R0]",*C* +2284,Hydantoin,C1NC(=O)NC(=O)1,O=C1CNC(=O)N1 +2285,Hydroxamic acid,C(=O)N[OH],O=CN[OH] +2286,Imine,C=[N!R],C=N +2287,Isolated alkene,"[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]=[$([CH2]),$([CH][CX4]),$(C([CX4])[CX4])]",*=* +2288,Ketene,C=C=O,C=C=O +2289,"Methylidene-1,3-dithiole",S1C=CSC1=S,S=C1SC=CS1 +2290,Michael acceptor (1),"C=!@CC=[O,S]",*=CC=C +2291,Michael acceptor (2),"[$([CH]),$(CC)]#CC(=O)[C,c]",*C(=O)C#* +2292,Michael acceptor (3),"[$([CH]),$(CC)]#CS(=O)(=O)[C,c]",*S(=O)(=O)C#* +2293,Michael acceptor (4),C=C(C=O)C=O,C=C(C=O)C=O +2294,Michael acceptor (5),"[$([CH]),$(CC)]#CC(=O)O[C,c]",*OC(=O)C#* +2295,N oxide,"[NX4,nX3][OX1]",*O +2296,"N-acyl-2-amino-5-mercapto-1,3,4-thiadiazole",s1c(S)nnc1NC=O,O=CNc1nnc(S)s1 +2297,N-c-halo,"NC[F,Cl,Br,I]",*CN +2298,N-halo,"[NX3,NX4][F,Cl,Br,I]",** +2299,N-hydroxylpyridine,n[OH],n[OH] +2300,Nitro group,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]",* +2301,N-nitroso,[#7]-N=O,NN=O +2302,Oxime (1),"[C,c]=N[OH]",*=N[OH] +2303,Oxime (2),"[C,c]=NOC=O",*=NOC=O +2304,Oxygen-nitrogen single bond,"[OR0,NR0][OR0,NR0]",** +2305,Perfluorinated chain,[CX4](F)(F)[CX4](F)F,FC(F)C(F)F +2306,Peroxide,OO,OO +2307,Phenol ester,c1ccccc1OC(=O)[#6],CC(=O)Oc1ccccc1 +2308,Phenyl carbonate,c1ccccc1OC(=O)O,OC(=O)Oc1ccccc1 +2309,Phosphor,P,P +2310,Phthalimide,"[cR,CR]~C(=O)NC(=O)~[cR,CR]",*~C(=O)NC(~*)=O +2311,Polycyclic aromatic hydrocarbon (1),"a1aa2a3a(a1)[a,A]=,:[a,A]-,:[a,A]=,:[a,A]3A=AA2",*1*=**2:*3:*1:*:*:*:*:3:*=**=2 +2312,Polycyclic aromatichydrocarbon (2),a21aa3a(aa1aaaa2)aaaa3,*1:*:*:*2:*:*3:*:*:*:*:*:3:*:*:2:*:1 +2313,Polycyclic aromatichydrocarbon (3),a31a(a2a(aa1)aaaa2)aaaa3,*1:*:*:*2:*(:*:1):*:*:*1:*:*:*:*:*:1:2 +2314,Polyene,[CR0]=[CR0][CR0]=[CR0],C=CC=C +2315,Quaternary nitrogen (1),"[s,S,c,C,n,N,o,O]~[nX3+,NX4+](~[s,S,c,C,n,N])~[s,S,c,C,n,N]",*~*(~*)~* +2316,Quaternary nitrogen (2),"[s,S,c,C,n,N,o,O]~[n+,N+](~[s,S,c,C,n,N,o,O])(~[s,S,c,C,n,N,o,O])~[s,S,c,C,n,N,o,O]",*~*(~*)(~*)~* +2317,Quaternary nitrogen (3),[*]=[N+]=[*],*=[N+]=* +2318,Saponine derivative,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2319,Silicon halogen,"[Si][F,Cl,Br,I]",*[Si] +2320,Stilbene,c1ccccc1C=Cc2ccccc2,C(=Cc1ccccc1)c1ccccc1 +2321,Sulfinic acid,"[SX3](=O)[O-,OH]",*S=O +2322,Sulfonic acid,"[C,c]S(=O)(=O)O[C,c]",*OS(*)(=O)=O +2323,Sulfonyl cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2324,Sulfur oxygen single bond,[SX2]O,OS +2325,Sulphate,OS(=O)(=O)[O-],OS(=O)(=O)[O-] +2326,Sulphur nitrogen single bond,[SX2H0][N],NS +2327,Thiobenzothiazole (1),c12ccccc1(SC(S)=N2),SC1=Nc2ccccc2S1 +2328,Thiobenzothiazole (2),c12ccccc1(SC(=S)N2),S=C1Nc2ccccc2S1 +2329,Thiocarbonyl group,"[C,c]=S",*=S +2330,Thiol (1),[S-],[SH-] +2331,Thiol (2),[SH],[SH] +2332,Three-membered heterocycle,"*1[O,S,N]*1",*1**1 +2333,Triflate,OS(=O)(=O)C(F)(F)F,OS(=O)(=O)C(F)(F)F +2334,Triphenyl methylsilyl,"[SiR0,CR0](c1ccccc1)(c2ccccc2)(c3ccccc3)",c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2335,Triple bond,C#C,C#C +2336,Aromatic NO2,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-c(:*):*",*c(:*):* +2337,Deuterium,[2H],[2HH] +2338,C13,[13#6],[13CH4] +2339,2-Chloropyridine,n1c(cccc1)Cl,Clc1ccccn1 +2340,"Si,B,Se atoms","[Si,B,Se]",* +2341,Hetero imides,[!#6]-[CH2]-N1C(=O)CCC(=O)1,*CN1C(=O)CCC1=O +2342,Poly ethers,O[CH2][CH2]O-!@[CH2][CH2]O,O[CH2][CH2]O[CH2][CH2]O +2343,Acyclic imines,"C-!@[NX2]=[C!R,#1]-C",C*=NC +2344,Alkyl esters of S or P,"[S,P](=O)OC",CO*=O +2345,Ugly P compounds,"P(=[O,S])[C,N]([C,N])[C,N]",**(*)P=* +2346,"Acyclic N-,=N and not N bound to carbonyl or sulfone","[N;!$(N-[C,S]=*)]-,=;!@[N;!$(N-[C,S]=*)]",NN +2347,Acyclic N-C-N,N-!@[CX4]-!@N,NCN +2348,Acyclic N-S,N-!@[SX2]-*,*SN +2349,"1,2-Dicarbonyl not in ring",O=[CX3]-!@[CX3]=O,O=CC=O +2350,"Carbamate, t-BOC protected",NC(OC([CH3])([CH3])[CH3])=O,[CH3]C([CH3])([CH3])OC(N)=O +2351,"Carbamate, Cbz protected",NC(O[CH2]c1ccccc1)=O,NC(=O)O[CH2]c1ccccc1 +2352,Carbamate include di-substitued N,OC(=O)-!@[NX3],NC(O)=O +2353,Acyl halide,"O=C-[F,Cl,Br,I]",*C=O +2354,Alpha halo carbonyl,"O=C-C-[F,Cl,Br,I]",*CC=O +2355,Sufonyl halide,"S(=O)(=O)-[F,Cl,Br,I]",*[SH](=O)=O +2356,N:C-SCH2 groups,[ND1]=C-!@[SX2]-[CH2D2],[CH2]SC=N +2357,26,N-C(=S)-N,NC(N)=S +2358,Terminal vinyl,[CH2D1]=[CD2]-!@*,*C=C +2359,28,S=P~*,*~P=S +2360,Thio cyanates,S-C#N,N#CS +2361,Thionyl,[Sv4](=O)(-!@[!#1])-!@[!#1],*S(*)=O +2362,N-Haloamines,"N-[F,Cl,Br,I]",*N +2363,N-C-Hal or cyano methyl,"N-C-[F,Cl,Br,I,$(C#N)]",*CN +2364,Alpha beta-unsaturated ketones; center of Michael reactivity,"[$(C#N),$(N(~O)~O),$(C=O),$(S(=O)=O),$(C(F)(F)F),Cl][C!H0]=[C!H0]",*C=C +2365,Aliphatic ketone not ring and not di-carbonyl,[C;!$(C=*)][C!R](=O)[CH2D2],CC([CH2])=O +2366,"Aliphatic ester, not lactones",C[C!R](=O)[O!R][CH2D2],CC(=O)O[CH2] +2367,"Long aliphatic chain, 6+",[CH2][CH2][CH2]-!@[CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2] +2368,Acyclic C=N-H,[NH1X2]=[C!R;!$(C(-N)(=[NH1])-N)],C=N +2369,Acyclic no not nitro,O-!@[N;!$(N(=O)=O);!$([N+](=O)[O-])],NO +2370,42,S-S,SS +2371,43,O~O,O~O +2372,Aziridine-like N in 3-membered ring,N~1~*~*1,*1~*~N~1 +2373,Aryl iodide,I-c:*,*:cI +2374,Aryl bromide,Br-c:*,*:cBr +2375,Multiple aromatic rings,a1aaa2a(a1)aaa(a2):a,*:*1:*:*:*2:*:*:*:*:*:2:*:1 +2376,S/PO3 groups,"[P,S](~O)(~O)~O",O~*(~O)~O +2377,Adamantyl,C12CC3CC(C1)CC(C2)C3,C1C2CC3CC1CC(C2)C3 +2378,Too many cyano groups (>1),C#N.C#N,C#N.C#N +2379,Too many COOH groups (>1),[CX3](=O)[OH1].[CX3](=O)[OH1],O=C[OH].O=C[OH] +2380,Amino acid,[NH2][CX4]C(=O)O,[NH2]CC(O)=O +2381,Chlorates,Cl~O,O~Cl +2382,High halogen content (>3),"[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I].[F,Cl,Br,I]",*.*.*.* +2383,Filter1_2_halo_ether,"[Cl,Br,I][CX4][CX4][$([O,S,N]*),Cl,Br,I]",*CC* +2384,Filter2_acyl_phosphyl_sulfonyl_halide,"[C,S,P](=O)[F,Cl,Br,I]",**=O +2385,Filter3_allyl_halide,"[F,Cl,Br,I][CX4]C=C",*CC=C +2386,Filter4_alpha_halo_carbonyl,"[Br,Cl,I][C!H0]C=[O,S]",*CC=* +2387,Filter5_azo,"[!#7,#1]~[NX2R0]=[NX2R0]~[!#7,#1]",*~N=N~* +2388,Filter6_benzyl_halide,"[Br,Cl,I][CX4]c",*Cc +2389,Filter7_diazo,[!#7]~[NX2]~[NX1],*~N~N +2390,Filter8_thio_isocyanat_diimin,"N=C=[N,O,P,S]",*=C=N +2391,Filter9_metal,"[!#1!#6!#7!#8!#9!#15!#16!#17]~[*,#1]",*~* +2392,Filter10_Terminal_vinyl,"[CH2]=[CH][N,O,P,S;R0]",*[CH]=C +2393,Filter11_nitrosamin,[NR0]~[NX2]~[OX1],N~N~O +2394,Filter12_nitroso,"[*,#1]~[NX2]~[OX1]",*~N~O +2395,Filter13_PS_double_bond,"S=P~[*,#1]",*~P=S +2396,Filter14_thio_oxopyrylium_salt,"c1ccc[s,o;X2]c1",*1ccccc1 +2397,Filter15_thiosulfate,[SX4](~S)(~O)(~O)~*,*~S(~O)(~O)~S +2398,Filter16_trialkyl_phosphin,[PX3]([#6])([#6])[#6],CP(C)C +2399,Filter17_trialkyl_phosphin2,[PX4](~[!O!S])([#6])([#6])[#6],*~P(C)(C)C +2400,Filter18_oxime_ester,"[!#7,#1]C=NO[C,S,P](=O)*",*C=NO*(*)=O +2401,Filter19_hydroxyimide_ester,O=C[NX3](C=O)OC(=O)*,*C(=O)ON(C=O)C=O +2402,Filter20_hydrazine,[Nv3X3][Nv3X3!H0],NN +2403,Filter21_cyanhydrin,[NX1]#C[CX4][OH],N#CC[OH] +2404,Filter22_sulfonium_salt,*[SX3](*)*,*S(*)* +2405,Filter23_ortho_quinone,C1(C=CC=CC1=O)=O,O=C1C=CC=CC1=O +2406,Filter24_react_imide,"*C([F,Cl,Br,I,$(OS(=O)(=O)*)])=[NX2]*",*N=C(*)* +2407,Filter25_sulfonyl_halide,"*S(=O)(=O)[F,Cl,Br,I]",*S(*)(=O)=O +2408,Filter26_alkyl_halide,"AA[CH2][F,Cl,Br,I,$(OS(=O)(=O)*)]",**[CH2]* +2409,Filter27_anhydride,"*[C,S](=O)O[C,S](=O)*",**(=O)O*(*)=O +2410,Filter28_halo_pyrimidine,"c1nc(ncc1)[Br,I]",*c1ncccn1 +2411,Filter29_thioester,"CC(=[OX1,SX1,NH])[SX2][*,#1]",*SC(=*)C +2412,Filter30_beta_halo_carbonyl,"[#6,#1]C(=O)CC[Br,I]",*CCC(*)=O +2413,Filter31_SO_bond,"[*,#1][SX2R0]O[*,#1]",*OS* +2414,Filter32_OO_bond,"[*,#1][OR0]O[*,#1]",*OO* +2415,Filter33_C10_alkyl,[CH3][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2],[CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH2][CH3] +2416,Filter34_isotope,"[2#1,3#1,13C,14C,15N,125I,23F,22Na,32P,33P,35S,45Ca,57Co,103Ru,141Ce]",* +2417,Filter35_PP_bond,P-P,PP +2418,Filter36_SS_double_bond,S=S,S=S +2419,Filter37_silicate,[Si]~O,O~[SiH4] +2420,Filter38_aldehyde,O=[CH]*,*[CH]=O +2421,Filter39_imine,C[CR0]=[NR0][*!O],*N=CC +2422,Filter40_epoxide_aziridine,"C1C[N,S,O]1",*1CC1 +2423,Filter41_12_dicarbonyl,*C(=O)C(=O)*,*C(=O)C(*)=O +2424,Filter42_12_dicarbonyl_tautomer,[*!$(C[OH])]=C([OH])C(=O)*,*C(=O)C(=*)[OH] +2425,Filter43_michael_acceptor_sp1,C#CC=O,C#CC=O +2426,Filter44_michael_acceptor2,"[#6,#1,OH0][C!$(C1(=O)C=CC(=O)C=C1)](=O)C=[C!$(C[Nv3X3,OH])]",*C(=O)C=C +2427,Filter45_allyl_halide2,"[Br,Cl,I][CX4]C=[C,N,P]",*CC=* +2428,Filter46_nhalide,"N[F,Cl,Br,I]",*N +2429,Filter47_SO2F,O=S(=O)(*)F,*S(=O)(=O)F +2430,Filter48_FOSO,O=S(*)OF,*S(=O)OF +2431,Filter49_halogen,"[*,#1]~[F,Cl,Br,I]~[*,#1]",*~*~* +2432,Filter50_grignard,"C[Mg][F,Cl,Br,I]",*[Mg]C +2433,Filter51_PN3,N[PX3](N)N,NP(N)N +2434,Filter52_NC_haloamine,"NC[F,Cl,Br,I]",*CN +2435,Filter53_para_quinones,O=C1C=CC(=O)C=C1,O=C1C=CC(=O)C=C1 +2436,Filter56_SS_bond,S-S,SS +2437,Filter57_polyphenol1,Oc1cc(O)cc(O)c1,Oc1cc(O)cc(O)c1 +2438,Filter58_polyphenol2,Oc1c(O)cc(O)cc1,Oc1ccc(O)c(O)c1 +2439,Filter59_phoshorous_ylide,C=P,C=P +2440,Filter60_Acyclic_N-S,N!@[SX2],N~S +2441,Filter61_phosphor_halide_and_P_S_bond,"[#15]~[F,Cl,Br,I,#16]",*~P +2442,Filter62_oxo_thio_halide,"[O,S]~[Cl,Br,I]",*~* +2443,Filter63_polyaromatic,a1aaaa2ccc3ccccc3c12,*1:*:*c2*(:*:1)ccc1ccccc12 +2444,Filter64_halo_ketone_sulfone,"[#6][C,S](=[O,S])C[F,Cl,Br,I]",*C*(=*)C +2445,Filter65_alkyl_sulfonate,"[#6][P,S](~[OX1])(~[OX1])O[C!H0]",CO*(C)(~O)~O +2446,Filter66_C4_perfluoralkyl,C(F)(F)C(F)(F)C(F)(F)C(F)(F),FC(F)C(F)(F)C(F)(F)C(F)F +2447,Filter67_S_or_O_C_triplebond_N,"[O,S]C#N",*C#N +2448,Filter68_anthracene_acridine,a1aaac2cc3ccccc3cc12,*1:*:*c2cc3ccccc3cc2*:1 +2449,Filter69_thio_carbonate,"[O,S]C(=[O,S])[O,S]",*C(*)=* +2450,Filter70_AlkylCN2,*(C#N)C#N,N#C*C#N +2451,Filter71_thio_anhydride,"*C(=[O,S])[O,S]C(=[O,S])*",*C(=*)*C(*)=* +2452,Filter72_hydrated_di_ketone,C(=O)C([OH])[OH],O=CC([OH])[OH] +2453,Filter73_thio_ketone,CC(=S)C,CC(C)=S +2454,Filter74_thiol,*[SX2H],*[SH] +2455,Filter75_alkyl_Br_I,"[C!H0][Br,I]",*C +2456,Filter76_S_ester,CC(=S)O,CC(O)=S +2457,Filter77_alkyl_NO2,"[*!#7]~[#6]-,=CN(~O)(~O)",*~CCN(~O)~O +2458,Filter78_bicyclic_Imide,*~@C1C(=O)NC(=O)C(~@*)1,*~C1C(~*)C(=O)NC1=O +2459,Filter79_maleimide,[CH]1C(=O)NC(=O)[CH]=1,O=C1[CH]=[CH]C(=O)N1 +2460,Filter80_Thioepoxide_aziridone,"[N,S]1[C,N,S][C,N,S]1",*1**1 +2461,Filter81_Thiocarbamate,"S!@C(=!@[O,S])!@[#7]",*=C(~N)~S +2462,Filter82_pyridinium,"[c,n]1[c,n][c,n][c,n][c,n]n(C)1",Cn1*:*:*:*:*1 +2463,Filter83_per_halo_chain,"[F,Cl,Br,I]C-,=;!@C([F,Cl,Br,I])-,=;!@C([F,Cl,Br,I])",*CC(*)C* +2464,Filter84_nitrogen_mustard,"[N,P,Se,S][C!H0]C[Br,Cl,I]",*CC* +2465,Filter85_keto_acrylonitrile,*C(=O)C(=!@[C!H0])C#N,*C(=O)C(=C)C#N +2466,Filter86_cyanamide,N#C[#7!$(N(C#N)=C(N)NC)],NC#N +2467,Filter87_crowns,"[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[O,N]-@[#6!$(*(~@*)(~@*)~@*)]@[#6!$(*(~@*)(~@*)~@*)]-@[N,O,S]-@C",*C~C*C~C*C~C*C +2468,Filter88_ene_sulfone,[C!H0]=CS(=O)(=O)*,*S(=O)(=O)C=C +2469,Filter89_hydroxylamine,"[*!$(C=O)]!@N!@O[*,#1]",*~N~O* +2470,Filter90_N_double_bond_S,N=!@S,N=S +2471,Filter92_trityl,*(c1ccccc1)(c1ccccc1)(c1ccccc1),c1ccc(*(c2ccccc2)c2ccccc2)cc1 +2472,Filter93_acetyl_urea,C(=O)!@N!@C(=O)[#7],NC(=O)~N~C=O +2473,Filter94_2_halo_pyridine,"c1nc(ccc1)[Br,I,Cl,F]",*c1ccccn1 +2474,Anhydride,C(=O)OC(=O),O=COC=O +2475,p-Nitrophenyl ester,C(=O)Oc1ccc([N+]([O-])=O)cc1,O=COc1ccc([N+](=O)[O-])cc1 +2476,Any carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2477,HOBT ester,C(=O)Onnn,nnnOC=O +2478,Aromatic azide,cN=[N+]=[N-],cN=[N+]=[N-] +2479,Imine2,"[#6,#8,#16]-[CH1]=[NH1]",*C=N +2480,Azocyanamide,[N;R0]=[N;R0]C#N,N#CN=N +2481,Cyanohydrin,N#CC[OH],N#CC[OH] +2482,Chloramidine,[Cl]C([C&R0])=N,CC(=N)Cl +2483,P/S halide,"[P,S][F,Cl,Br,I]",** +2484,Quaternary,"[C+,Cl+,I+,P+,S+]",* +2485,Unacceptable atoms,[!#6;!#7;!#8;!#16;!#1;!#3;!#9;!#11;!#12;!#15;!#17;!#19;!#20;!#30;!#35],* +2486,Triacyloxime,C(=O)N(C(=O))OC(=O),O=CON(C=O)C=O +2487,b-Carbonyl quaternary nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2488,Benzylic quaternary nitrogen,cC[N+],cC[N+] +2489,Phosphorane,C=P,C=P +2490,Lawesson reagent derivatives,P(=S)(S)S,SP(S)=S +2491,Cyanophosphonate,P(OCC)(OCC)(=O)C#N,CCOP(=O)(C#N)OCC +2492,Sulfonate,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2493,Heteroaryl sulfonate,"a-S(=O)(=O)-O[$([a&!#6]),$(c[a&!#6]),$(cc[a&!#6]),$(ccc[a&!#6]),$(cccc[a&!#6]),$(ccccc[a&!#6])]",*OS(*)(=O)=O +2494,Sulfate ester,"COS(=O)O[C,c]",*OS(=O)OC +2495,Polyacidic,"[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH].[C,S,P](=O)[OH]",O=*[OH].O=*[OH].O=*[OH].O=*[OH] +2496,Thiol,[SH],[SH] +2497,Benzhydrol,[OH1]-C(-c1ccccc1)c2ccccc2,OC(c1ccccc1)c1ccccc1 +2498,Dihydroxybenzene,[OH1]c1ccc([OH1])cc1,[OH]c1ccc([OH])cc1 +2499,"2,3,4-Trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2500,"2,4,5-Trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2501,Allene,*=C=*,*=C=* +2502,Azide,"[$(*-[NX2-]-[NX2+]#[NX1]),$(*-[NX2]=[NX2+]=[NX1-]),$(N=N=N)]",* +2503,Azoalkanal,[N;R0]=[N;R0]CC=O,N=NCC=O +2504,Hydrazothiourea,N=NC(=S)N,NC(=S)N=N +2505,Hemiacetal,[#6]-O[CH1](-[#6])[OH1],CO[CH](C)[OH] +2506,Ester,[#6]-C(=O)O-[#6],COC(C)=O +2507,Imine 1,"[#6,#8,#16]-C(=[NH1])[#6,#8,#16]",*C(*)=N +2508,Imine 3,C=[NH],C=N +2509,Thioketone,CC(=S)C,CC(C)=S +2510,Thionoester,COC(=S)C,COC(C)=S +2511,Thioamide,CC(=S)N,CC(N)=S +2512,Long chain hydrocarbon,[CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0][CD2;R0],CCCCCC +2513,Long aliphatic chain,"[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]-&!@[N,C,S,O]",******* +2514,Unbranched chain,"[$([A&D2]),$([A&D1])]!@[A&D2]!@[A&D2]!@[A&D2]!@[A&D2]!@[$([A&D2]),$([A&D1])]",*~*~*~*~*~* +2515,Dye 25,acC=&!@Cca,*cC=Cc* +2516,Isonitrile,[N+]#[C-],[C-]#[NH+] +2517,Thiocyanate,SC#N,N#CS +2518,Dye 16 (1),"c[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c +2519,Nitro aromatic 2+,"a-[$([NX3](=O)=O),$([NX3+](=O)[O-])].a-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",**.** +2520,Dye 29,"[$([NX3](=O)=O),$([NX3+](=O)[O-])]-caac-[$(N(C)C),$([NH]C),$([NH2])]",*c*:*c* +2521,Dye 1 (1),"c1cccc(C(=O)[C,c]([#7])=,:[C,c]([#7])C2(=O))c12",N*1=*(N)C(=O)c2ccccc2C1=O +2522,Dye 7,"N=C1[#6]:,=[#6]C(=[C,N])[#6]:,=[#6]1",*=C1C:CC(=N)C:C1 +2523,Dye 11,"*=,:[#6]C([#6]=,:*)[#6]=,:*",*=CC(C=*)C=* +2524,Dye 9,ac-*=&!@*-&!@C(=O)-&!@ca,*c*=*C(=O)c* +2525,Dye 32,"c1cccc2C(=O)C(C:,=*)C(=O)c12",*:CC1C(=O)c2ccccc2C1=O +2526,Dye 6,c12cccc(C(=O)C(ca)C(=O)3)c2c3ccc1,*cC1C(=O)c2cccc3cccc(c23)C1=O +2527,Dye 22,NS(=O)(=O)c1cccc([#7])c1,Nc1cccc(S(N)(=O)=O)c1 +2528,Dye 2,OCccCO,OCccCO +2529,Dye 26,c1ccccc1-n2nnnc2[CH2]*,*[CH2]c1nnnn1-c1ccccc1 +2530,Perhalo_ketone,"O=CC(-[F,Cl,Br,I])([F,Cl,Br,I])-[F,Cl,Br,I]",*C(*)(*)C=O +2531,Beta halo carbonyl,"O=CCC[F,Cl,Br,I]",*CCC=O +2532,4-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[n]:[c,n]:[c,n]1",*c1*:*n*:*1 +2533,2-Halopyridine,"[F,Cl,Br][c]1:[c,n]:[c,n]:[c,n]:[c,n]:[n]1",*c1*:*:*:*n1 +2534,Hetero_hetero,"*[N,S,O]-&!@[N,S,O][#6]",***C +2535,Disulfide,SS,SS +2536,Vinyl michael acceptor1,"[#6]-[CH1]=C-C(=O)[#6,#7,#8]",*C(=O)C=CC +2537,Vinyl michael acceptor2,"[CH2]=C-C(=O)[#6,#7,#8]",*C(=O)C=C +2538,Michael acceptor 5,N#CC(=C)C#N,C=C(C#N)C#N +2539,Michael acceptor 6,"[#6,#7]-&!@[#6](=&!@[CH])-&!@C(=O)-&!@[C,N,O,S]",*C(=[CH])C(*)=O +2540,Alkynyl michael acceptor1,"[#6]-C#CC(=O)[#6,#7,#8]",*C(=O)C#CC +2541,Alkynyl michael acceptor2,"[CH1]#CC(=O)-[#6,#7,#8]",*C(=O)C#C +2542,Nitroalkane,"C[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*C +2543,Nitrate,"[#6]-O-[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*OC +2544,Oxalyl,O=C-&!@C=O,O=CC=O +2545,Dipeptide,*-C(=O)-&!@[NH]-C-&!@C(=O)-&!@[NH]-*,*NC(=O)CNC(*)=O +2546,Quaternary nitroxy,C[N+](-[O-])(C)C,C[N+](C)(C)[O-] +2547,Triphenylphosphine,a-P(-a)-a,*P(*)* +2548,Phosphoric acid,[OH]-P(=O)(-O)-*,*P(=O)(O)O +2549,Phosphoric ester,COP(=O)(-*)O,*P(O)(=O)OC +2550,Di/triphosphate,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2551,Tri phosphoric esters,[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6].[#6]OP(=O)(*)O[#6],*P(=O)(OC)OC.*P(=O)(OC)OC.*P(=O)(OC)OC +2552,Phosphoramide,NP(=O)(N)N,NP(N)(N)=O +2553,Phenalene,c1(c)c2c(c)cccc2ccc1,cc1cccc2cccc(c)c12 +2554,Poly(azo(anthracene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1[c,n]c3:[c,n]:[c,n]:[c,n]:[c,n]:c3[c,n]2",*1:*:*c2*c3*:*:*:*c3*c2*:1 +2555,Poly(azo(phenanthrene)),"c12:[c,n]:[c,n]:[c,n]:[c,n]:c1:[c,n]:[c,n]:c3:[c,n]:[c,n]:[c,n]:[c,n]:c23",*1:*:*c2c(*:1)*:*c1*:*:*:*c12 +2556,Dye 31,a1aaac2ac3acac4aaac(c34)c12,*1:*:*c2c(*:1)*c1*c*c3*:*:*c2c31 +2557,Dye 4,c12ccccc1C(=O)c3ccccc3C2=O,O=C1c2ccccc2C(=O)c2ccccc21 +2558,Dye 8,c12cccc(C(=O)N(-&!@C)C(=O)3)c2c3ccc1,CN1C(=O)c2cccc3cccc(c23)C1=O +2559,"Epoxide, aziridine, thioepoxide","C1[O,S,N]C1",*1CC1 +2560,Propiolactone,C1(=O)OCC1,O=C1CCO1 +2561,b-Lactam,N1CCC1=O,O=C1CCN1 +2562,Cycloheximide,O=C1CCCC(N1)=O,O=C1CCCC(=O)N1 +2563,Aromatic sulfonic ester,"[#6,#7]-S(=O)(=O)Oc",*S(=O)(=O)Oc +2564,Quinone,"[$([o,n]=c1ccc(=[o,n])cc1),$([O,N]=C1C=CC(=[O,N])C=C1),$([O,N]=C1[#6]:,=[#6]C(=[O,N])[#6]:,=[#6]1)]",* +2565,Saponin,O1CCCCC1OC2CCC3CCCCC3C2,C1CCC(OC2CCC3CCCCC3C2)OC1 +2566,Monensin,O1CCCCC1C2CCCO2,C1CCC(C2CCCO2)OC1 +2567,Squalestatin,C12OCCC(O1)CC2,C1CC2CCC(O1)O2 +2568,Cyanidin,[OH]c1cc([OH])cc2=[O+]C(=C([OH])Cc21)c3cc([OH])c([OH])cc3,[OH]C1=C(c2ccc([OH])c([OH])c2)[O+]=c2cc([OH])cc([OH])c2C1 +2569,Cytochalasin,O=C1NCC2CCCCC21,O=C1NCC2CCCCC21 +2570,"2,2-Dimethyl_4,5-dicarboxy_dithiole",C1(C)(C)SC(C(=O)O)=C(C(=O)O)S1,CC1(C)SC(C(O)=O)=C(C(O)=O)S1 +2571,"2,3,4_trihydroxyphenyl",c([OH])c([OH])c([OH]),[OH]cc([OH])c[OH] +2572,"2,3,5_trihydroxyphenyl",c([OH])c([OH])cc([OH]),[OH]ccc([OH])c[OH] +2573,Acid_anhydrides,C(=O)OC(=O),O=COC=O +2574,Acid_halides,"[S,C](=[O,S])[F,Br,Cl,I]",**=* +2575,Acridine,c1c2cc4ccccc4nc2ccc1,c1ccc2nc3ccccc3cc2c1 +2576,Active_phosphate,"P(=S)([OH1,O$(O[#6])])([OH1,O$(O[#6])])[S,O]",*P(*)(*)=S +2577,Acyl_cyanide,C(=O)-C#N,N#CC=O +2578,Adjacent_ring_double_bonds,[*;R]=[*;R]=[*;R],*=*=* +2579,Aliphatic_triflate,COS(=O)(=O)C(F)(F)F,COS(=O)(=O)C(F)(F)F +2580,Alkyl_halides,"[Br,Cl,I][CX4;CH,CH2]",*C +2581,Alkylenamine,"[C;H1$(C([#6;!$(C=O)])),H0$(C([#6;!$(C=O)])[#6;!$(C=O)])]=[CH1]!@N([#6;!$(C(=O))])[#6;!$(C(=O))]",CN(C)~[CH]=C +2582,Alpha_halo_carbonyl,"[C;!$(C[N])](=O)!@[C;h1,h2;H1,H2][F,Cl,Br,I]",*C~C=O +2583,Amino_naphtalimide,c1(N)ccc(C(=O)NC3(=O))c(c3ccc2)c21,Nc1ccc2c3c(cccc13)C(=O)NC2=O +2584,Aminonitrile,NC#N,NC#N +2585,Any_carbazide,O=*N=[N+]=[N-],[N-]=[N+]=N*=O +2586,Aromatic_azides,"c[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*c +2587,Azanitrone,N=[N+]([O-])C,C[N+](=N)[O-] +2588,Azoalkanals,[N;R0]=[N;R0]CC=O,N=NCC=O +2589,Azobenzene,c1ccccc1[N!r]=[N!r]c2ccccc2,c1ccc(N=Nc2ccccc2)cc1 +2590,B-carbonyl_quaternary_nitrogen,"C(=O)CC[N+,n+]",*CCC=O +2591,Benzylic_quaternary_nitrogen,"cC[N+,NX4]",*Cc +2592,Beta-carbonyl_quaternary_nitrogen,"C(=O)C[N+,n+,NX4,nX4]",*CC=O +2593,Beta-fluoro-ethyl-on,"[C;H2$(CF),H1$(C(F)F)]!@[CH2][N,O]",*[CH2]~C +2594,Biotin_analogue,C12C(NC(N1)=O)CSC2,O=C1NC2CSCC2N1 +2595,Carbazides,"C(=O)[$([NX2-]-[NX2+]#[NX1]),$([NX2]=[NX2+]=[NX1-]),$(N=N=N)]",*C=O +2596,CCl3-CHO_releasing,"C(Cl)(Cl)(Cl)C([O,S])[NX3]",*C(N)C(Cl)(Cl)Cl +2597,Conjugated_dithioether,SC(=[!r])S,*=C(S)S +2598,Crown_ether_12cro4,O1CCOCCOCCOCC1,C1COCCOCCOCCO1 +2599,Crown_ether_15cro5,O1CCOCCOCCOCCOCC1,C1COCCOCCOCCOCCO1 +2600,Crown_ether_16cro6,O1CCOCCOCCOCCOCCOCC1,C1COCCOCCOCCOCCOCCO1 +2601,Crown_ethers,[O;R1][C;R1][C;R1][O;R1][C;R1][C;R1][O;R1],OCCOCCO +2602,Di_and_triphosphates,P(=O)([OH])OP(=O)[OH],O=P([OH])OP(=O)[OH] +2603,Diacetylene,C#CC#C,C#CC#C +2604,Diazoalkane,C=[N+]=[N-],C=[N+]=[N-] +2605,Diazonium_salt,[N+]#N,N#[NH+] +2606,Diene,C!@=[CH1]-C!@=[CH1]-[CX3](=O),C~[CH]C~[CH]C=O +2607,Dinitrobenzene_1,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc1",*c1ccccc1* +2608,Dinitrobenzene_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])c1",*c1ccc(*)cc1 +2609,Dinitrobenzene_3,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1cccc(*)c1 +2610,Dithiocarbamate,NC(=S)S,NC(S)=S +2611,Dithiole-2-thione,S1SC=CC1=S,S=C1C=CSS1 +2612,Dithiole-3-thione,S1C=CSC1=C,C=C1SC=CS1 +2613,Dithiomethylene_acetal,S[C;!$(C=*)]S,SCS +2614,Enyne,C=!@CC#C,C#CC=C +2615,"Epoxides,_thioepoxides,_aziridines","C1[O,S,N]C1",*1CC1 +2616,Ester_of_HOBT,C(=O)Onnn,nnnOC=O +2617,Flavin,"c1cccc(NC(=NC(=[N,S,O])NC(=O)3)C3=N2)c12",*=C1NC(=O)C2=Nc3ccccc3NC2=N1 +2618,Fluorescein,c1cc(O)cc(OC(=CC(=O)C=C3)C3=C2)c12,Oc1ccc2c(c1)OC1=CC(=O)C=CC1=C2 +2619,Fluorinated_carbon_1,C(C(CF)F)F,FCC(F)CF +2620,Fluorinated_carbon_2,C(C(F)F)(F)F,FC(F)C(F)F +2621,Four_member_lactones,C1(=O)OCC1,O=C1CCO1 +2622,Geminal_amines,[NH1;!r][CX4][NH1;!r],NCN +2623,Geminal_dinitriles,N#CCC#N,N#CCC#N +2624,"Halo-pyridine, -diazoles and -triazoles","[Cl,Br,I]c1[c,n][c,n][c,n][c,n]n1",*c1*:*:*:*n1 +2625,Imidazolium,c1[n+]([#6])ccn1([#6]),Cn1cc[n+](C)c1 +2626,Imines_(not_ring),"[#6][CR0](=[NR0,OR0])[#6]",*=C(C)C +2627,Isocyanates_and_isothiocyanates,"N=C=[S,O]",*=C=N +2628,Lawesson_reagent_derivatives,P(=S)(S)S,SP(S)=S +2629,Michael_phenyl_ketone,c1ccccc1C(=O)C=!@CC(=O)!@*,*~C(=O)C=CC(=O)c1ccccc1 +2630,Nitrobenz-azadiazole_1,"c1ccc(n[o,s]n2)c2c1[$([NX3](=O)=O),$([NX3+](=O)[O-])]",*c1cccc2n*nc12 +2631,Nitrobenz-azadiazole_2,"c1c([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc(n[o,s]n2)c2c1",*c1ccc2n*nc2c1 +2632,Nitrosamine,N-[N;X2](=O),NN=O +2633,Noname,"N1=C[S,NH1]C(=[C,N,P][C,N,O,P])C1(=O)",**=C1*C=NC1=O +2634,N-oxide_aliphatic,[N+!$(N=O)][O-X1],[N+][O-] +2635,N-S (not sulfonamides),[#6][S!$(S(~[OD1])~[OD1])][N;H0],CSN +2636,Orthoester,C(O)(O)[OH],OC(O)[OH] +2637,O-tertbutylphenol,c1c([OH1])c(C(C)(C)C)ccc1,CC(C)(C)c1ccccc1[OH] +2638,Oxobenzothiepine,C1(=O)C=CCSC=C1,O=C1C=CCSC=C1 +2639,P_or_S_halides,"[P,S][Cl,Br,F,I]",** +2640,P-aminoaryl_diazo,Nc1aaa(N!@=N)aa1,Nc1*:*:*(N~N):*:*1 +2641,PCP,PCP,PCP +2642,Paranitrophenyl_esters,"C(=O)Oc1ccc([$([NX3](=O)=O),$([NX3+](=O)[O-])])cc1",*c1ccc(OC=O)cc1 +2643,Pentahalophenyl,"c1c([F,Cl])c([F,Cl])c([F,Cl])c([F,Cl])c1([F,Cl])",*c1cc(*)c(*)c(*)c1* +2644,Pentafluorophenyl_esters,C(=O)Oc1c(F)c(F)c(F)c(F)c1(F),O=COc1c(F)c(F)c(F)c(F)c1F +2645,Phenanthrene,c12cccc3c1c4c(cc3)cccc4cc2,c1cc2ccc3cccc4ccc(c1)c2c34 +2646,Phenylester,C(=O)!@Oc1ccccc1,O=C~Oc1ccccc1 +2647,Phosphonate_esters,[#6]P(=O)(~O)O[#6],COP(C)(=O)~O +2648,Phosphoramides,NP(=O)(N)N,NP(N)(N)=O +2649,Phosphorus_halide,"[S,P][F,Cl,Br,I]",** +2650,Polyenes,C=CC=CC=CC=C,C=CC=CC=CC=C +2651,Polyene_chain_between_aromatics,cC=CC=CC=Cc,cC=CC=CC=Cc +2652,Polyines,CC#CC#CC,CC#CC#CC +2653,Polynuclear_aromatic_1,c1cccc(cc(cccc2)c2c3)c13,c1ccc2cc3ccccc3cc2c1 +2654,Polynuclear_aromatic_2,c1cccc(c(cccc2)c2cc3)c13,c1ccc2c(c1)ccc1ccccc12 +2655,Polysulfide,*[SX2][SX2][SX2]*,*SSS* +2656,Sulphur_halide,"[#16][F,Cl,Br,I]",*S +2657,Pyrene_fragments,c1c2cccc3c2c4c(cc3)cccc4c1,c1cc2ccc3cccc4ccc(c1)c2c34 +2658,Pyrylium,c1ccc[o+]c1,c1cc[o+]cc1 +2659,Reactive_carbonyls,"[C;!r](=[O,S])[S;!r]",*=CS +2660,Ring_triple_bond,"[C,c;R]#[C,c;R]",*#* +2661,S=N (not_ring),[S;R0]=[N;R0],N=S +2662,Sulfonate_ester,O=[SX4](=O)OC,COS(=O)=O +2663,Sulfonyl_cyanide,S(=O)(=O)C#N,N#CS(=O)=O +2664,Sulphate_ester,"COS(=O)O[C,c]",*OS(=O)OC +2665,Sulphonates,"COS(=O)(=O)[C,c]",*S(=O)(=O)OC +2666,Sulphur_nitrogen_single_bond,[SX2H0]!@[N],N~S +2667,Tetraazinane,C1NNC=NN1,C1NNC=NN1 +2668,Thioles_(not_aromatic),[!a][SX2;H1],*S +2669,Thiophosphothionate,"P(=S)(-[S;H1,H0$(S(P)C)])(-[O;H1,H0$(O(P)C)])(-N(C)C)",CN(C)P(O)(=S)S +2670,Three_membered_heterocycle,"*1[O,S]*1",*1**1 +2671,Tri_pentavalent_S,"[#16v3,#16v5]",* +2672,Triazole,c1cnnn1!@C!@[NH1][#6],C[NH]~C~n1ccnn1 +2673,Triphenyl_boranyl,B(c1ccccc1)(c2ccccc2)c3ccccc3,c1ccc(B(c2ccccc2)c2ccccc2)cc1 +2674,Triphenylphosphines,P(c1aaaaa1)(c1aaaaa1)(c1aaaaa1),*1:*:*c(P(c2*:*:*:*:*2)c2*:*:*:*:*2)*:*:1 +2675,Triphenyl_silyl,[Si](c1ccccc1)(c2ccccc2)(c3ccccc3),c1ccc([Si](c2ccccc2)c2ccccc2)cc1 +2676,Vinyl_halide,"[Cl,Br,I]C=[!O!R]",*C=* +2677,Vinyl_sulphone,"[#6][CH1]!@=[CH1][S;H1,H0$(S(C)C)](=O)(=O)",C[CH]~[CH]S(=O)=O +2678,Sulphates,[#6]S(=O)(=O)O,CS(O)(=O)=O +2679,Tropone,C1C(=O)C=CC=CC=1,O=C1C=CC=CC=C1 +2680,Oxime,"[#6]C(=!@N[$(OC),$([OH])])[#6]",*N=C(C)C +2681,Hydrazone,[#6]C(=!@NNa)[#6],*NN=C(C)C +2682,Nitrosone_not_nitro,[$(N(~!@[#6])!@O);!$([N+]([O-])=O)],* +2683,Thiocarbonyl_group,C=S,C=S +2684,Enamine_like,C=[NH],C=N +2685,Analine,"c1ccccc1[NH2,NH3+]",*c1ccccc1 +2686,Acid_anhydrides_2,"[#6]C(=O)!@OC(=!@[N,O])[#6]",*=C(C)O~C(C)=O +2687,Trifluroacetate_amide,FC(F)(F)C(=O)N,NC(=O)C(F)(F)F +2688,Triple_bond,[#6]C#[CH],CC#C +2689,Thiatetrazolidine,"[$(Sc1nnn[nH,n-]1),$(Sc1nn[nH,n-]n1)]",* +2690,Glycol,"[#6][O;R0][$(C([#6])[#6]),$([CH][#6]),$([CH2])][O;R0][#6]",CO*OC +2691,Oxy-amide,[#6]C(=O)!@C!@C(=O)N,CC(=O)~C~C(N)=O +2692,Formate_formide,"O=[CH][O,N][#6]",C*[CH]=O +2693,Pyranone,O=C1C=COC=C1,O=C1C=COC=C1 +2694,Coumarin,c1cc2C=CC(=O)Oc2cc1,O=C1C=Cc2ccccc2O1 +2695,Aminothiazole,s1ccnc1[N!H0],Nc1nccs1 +2696,Thiazolidinone,O=C1CSCN1,O=C1CSCN1 +2697,Thiomorpholinedione,N1C(=O)CSCC1=O,O=C1CSCC(=O)N1 +2698,Oxepine,O1C=CC=CC=C1,C1=CC=COC=C1 +2699,Phenylethene,c1ccccc1!@[CH]=!@[C!H0],C=[CH]~c1ccccc1 +2700,Ethene,C=[CH2],C=C +2701,Cyclobutene,C1CC=C1,C1CC=C1 +2702,Poly_sub_atomatic,*!@c1c(!@*)c(!@*)c(!@*)c(!@*)c1,*~c1cc(~*)c(~*)c(~*)c1~* +2703,Isotopes,"[2#1,3#1,11C,11c,14C,14c,125I,32P,33P,35S]",* +2704,Metal_carbon_bond,"[#6;$([#6]~[#3,#11,#12,#13,#19,#20,#26,#27,#28,#29,#30])]",C +2705,Aromatic_N-oxide_more_than_one,[n+][O-X1].[n+][O-X1],[n+][O-].[n+][O-] +2706,Nitro_more_than_one,[N+](=O)[O-].[N+](=O)[O-],O=[N+][O-].O=[N+][O-] +2707,Sulphur atom (1),[SX2H1],[SH] +2708,Sulphur atom (2),"[$([SX2H0]);!$([S][#6X3,#7X2]);!$([S][CX4H0])]",* +2709,Sulphur atom (3),"[$([SX2H0][#6X3,#7X2]);!$([S](~[#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2710,Sulphur atom (4),[$([S][*D4H0]);$([SX2H0])],* +2711,Sulphur atom (5),"[$([SX2H0]([#6X3,#7X2])[#6X3,#7X2]);!$([S][CX4H0])]",* +2712,Sulphur atom (6),[sX2r5],s +2713,Sulphur atom (7),[$([#16X3](=[OX1]));$([#16]);!$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2714,Sulphur atom (8),[$([#16X3](=[OX1]));$([#16]);$([#16X3](=[OX1])[#6X3](~[#7X2]))],* +2715,Aldehyde carbon atoms,[$([CX3H1](=O)[#6])],* +2716,Phosphor with double bonded sulphur,[$([PX4]);$([P]=[S])],* +2717,sp3 hybridized carbon atoms (1),[$([CX4]([#6X3])([#6X3])[#6X3]);!$([CH0])],* +2718,sp3 hybridized carbon atoms (2),"[$([CX4][N]);!$([CH0]);!$([C][N]([#6X3,#7X2])[#6X3,#7X2]);!$([C][N]=[#6X3]);!$([CX4][NX3][C]=[O])]",* +2719,sp3 hybridized carbon atoms (3),"[!$([CH0]);$([CX4]([#6X3])[#6X3]),$([CX4][#7]=[#6X3]),$([CX4]([#8])[#8]);!$([CX4]([#8])[#8][C]=[O])]",* +2720,sp3 hybridized carbon atoms (4),[$([CX4][S]);!$([CH0]);!$([C][S]=[O])],* +2721,sp3 hybridized carbon atoms (5),"[$([CX4][#6X3]~[#8]),$([CX4][#6X3](~[#7])~[#7]),$([CX4][#6X2]),$([CX4][CX3]=[CX3]-[#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3]);!$([CX4][#6X3](=[#8])-[#8]);!$([CX4][CX3]([CX3])=[CX3]-[#6X3])]",* +2722,sp3 hybridized carbon atoms (6),[$([CX4][O]);!$([CH0]);!$([C][O][C]=[O]);!$([CX4]1[O][C]1)],* +2723,sp3 hybridized carbon atoms (7),[$([CX4][#6X3]);!$([CH0]);!$([CX4][C](=[O])[NX3])],* +2724,sp3 hybridized carbon atoms (8),"[$([CX4][#7](~[#6X3,#7X2])~[#6X3,#7X2]);!$([CH0])]",* +2725,sp3 hybridized carbon atoms (9),[$([CX4][S](=[O])=[O]);!$([CH0])],* +2726,sp3 hybridized carbon atoms (10),"[CX4;CH1,CH2;!$([CX4][NX3H1][C]=[O])]",C +2727,sp3 hybridized carbon atoms (11),[CX4H3;!$([CX4][NX3H1][C]=[O])],C +2728,sp3 hybridized carbon atoms (12),[$([CX4][NX3H1][C]=[O]);!$([CH0])],* +2729,sp2 hybridized carbon atoms (1),"[$([CX3H2]);$([C]=[#6X3,#7X2]-[#6X3,#7X2])]",* +2730,sp2 hybridized carbon atoms (2),"[$([CX3H1]);$([C]=[#6X3,#7X2]-[#6X3,#7X2]);!$([C](-[#6X3,#7X2])=[#6X3,#7X2]-[#6X3,#7X2])]",* +2731,sp2 hybridized carbon atoms (3),[$([cH1]);$([c](:[#7]):[#7])],* +2732,sp2 hybridized carbon atoms (4),"[$([ch1]);!$([ch1]1:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]:[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NX3]-[#6X3,#7X2]):[c]:[c]1);$([ch1]1:[c](-[NX3]):[c]:[c]:[c]:[c]1),$([c]1:[c]:[c]:[c](-[NX3]):[c]:[c]1)]",* +2733,sp2 hybridized carbon atoms (5),"[$([CX3]);$([CX3]=[CX3]);!$([CH0]);!$([CX3](-[#6X3,#7X2])=[CX3]);!$([CX3]=[CX3]-[#6X3,#7X2])]",* +2734,sp2 hybridized carbon atoms (6),[$([cH1]);$([c]:[#16])],* +2735,sp2 hybridized carbon atoms (7),"[$([ch1]);$([c]1:[c]:[c]:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]1),$([c]1:[c]:[c]:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]1);!$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1)]",* +2736,sp2 hybridized carbon atoms (8),"[$([ch1]);!$([c]1:[c]:[c]:[c](-[O]-[C]=[O]):[c]:[c]1);$([c]1:[c]:[c]:[c](-[NH]-[C]=[O]):[c]:[c]1),$([c]1:[c]:[c]:[c](-[O,SX2]):[c]:[c]1)]",* +2737,sp2 hybridized carbon atoms (9),[$([cH1]);$([c]1:[c]:[#16]:[c]:[c]1)],* +2738,sp2 hybridized carbon atoms (10),"[$([ch1]);$([ch1]1:[c](~[#7X2H0]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]1:[c](~[#7X3H1]~[cX3,CX3]):[c]:[c]:[c]:[c]1),$([ch1]:[c]-[O,SX2]);!$([ch1]:[c]-[O]-[C]=[O])]",* +2739,sp2 hybridized carbon atoms (11),"[$([CX3H1,cX3H1]);!$([ch1]1:[c]:[c]:[#7]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]:[c]1);!$([ch1]1:[c]:[#7]:[c]:[c]1);!$([ch1]:[#7])]",* +2740,sp2 hybridized carbon atoms (12),"[$([ch1]1:[c]:[c]:[#7]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]:[c]1),$([ch1]1:[c]:[#7]:[c]:[c]1),$([ch1]:[#7])]",* +2741,Nitrogen atoms (1),"[$([NX3H0]);!$([NX3][#6X3,#7X2])]",* +2742,Nitrogen atoms (2),"[$([NX3]);$([H1,H2])]",* +2743,Nitrogen atoms (3),[$([N]([#6X3]1)[#6X3]=[#6X3][#6X4][#6X3]=1)],* +2744,Nitrogen atoms (4),"[$([NX3H0]);$([NX3][#6X3,#7X2]);!$([NX3]([#6X3,#7X2])[#6X3,#7X2])]",* +2745,Nitrogen atoms (5),"[$([nr6]),$([NX2]=[C])]",* +2746,Nitrogen atoms (6),"[$([N]);$([NX3H0]([#6X3,#7X2])[#6X3,#7X2]),$([NX2H1][C]=[O])]",* +2747,Nitrogen atoms (7),[nr5H0],n +2748,SA01,[#6]-1-[#6]-[#6]-[#6]-4-[#6](-[#6]-1)-[#6]-2-[#6](-[#6]-3-[#6](-[#6]-[#6]-2)-[#6]-[#6]-[#6]-3)-[#6]-[#6]-4,C1CCC2C(C1)CCC1C3CCCC3CCC21 +2749,SA03,c1cc-2c(cc1)-[#6]-[#6]-[#6](-[#6]-2-[#6])-[#6],CC1CCc2ccccc2C1C +2750,SA04,c1cc(ccc1)-[#6]=[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(C=Cc2ccccc2)cc1 +2751,SA05,c1cc(ccc1)-[#6]-[#6]-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(CCc2ccccc2)cc1 +2752,SA07,c1cc(ccc1)-[#6](=[#6]-c2ccccc2)-c3ccccc3,c1ccc(C=C(c2ccccc2)c2ccccc2)cc1 +2753,SA11,[#6]-2(=[#6]-c1ccccc1-[#8]-[#6]-2=[#8])-c3ccccc3,O=C1Oc2ccccc2C=C1c1ccccc1 +2754,SA12b,[#8]=[#6](-c1ccccc1)-[#6]=[#6]-c2ccccc2,O=C(C=Cc1ccccc1)c1ccccc1 +2755,SA15c,c1cc(ccc1-[#8]-[#1])-[#6](-c2ccccc2)=[#8],[H]Oc1ccc(C(=O)c2ccccc2)cc1 +2756,SA16,c1cc(ccc1)-[#6](-c2ccccc2)=[#6](-[Cl])-[Cl],ClC(Cl)=C(c1ccccc1)c1ccccc1 +2757,SA17,c1cc(ccc1)-[#6](-c2ccccc2)-[#6],CC(c1ccccc1)c1ccccc1 +2758,SA18,c1c(cccc1)-c2ccccc2,c1ccc(-c2ccccc2)cc1 +2759,SA19,c1c(cccc1)-c2ccccc2-[Cl],Clc1ccccc1-c1ccccc1 +2760,SA20c,c1c(cccc1)-c2ccc(cc2)-[#8]-[#1],[H]Oc1ccc(-c2ccccc2)cc1 +2761,SA21,c1cc-3c(cc1)-[#8]-c2ccccc2-[#8]-3,c1ccc2c(c1)Oc1ccccc1O2 +2762,SA23,c1cc(c(cc1)-[#6](=[#8])-[#8]-[#6])-[#6](-[#8]-[#6])=[#8],COC(=O)c1ccccc1C(=O)OC +2763,SA24,c1c(ccc(c1)-[#8]-[#1])-[#6](-[#8]-[#6])=[#8],[H]Oc1ccc(C(=O)OC)cc1 +2764,SA25c,[#8](-[#6])-c1ccc(cc1)-[#8]-[#1],[H]Oc1ccc(OC)cc1 +2765,SA30a,c1cc(ccc1-[Cl])-[#8]-c2ccc(cc2-[Cl])-[Cl],Clc1ccc(Oc2ccc(Cl)cc2Cl)cc1 +2766,SA30b,c1cc(ccc1-[#7](=[#8])=[#8])-[#8]-c2ccc(cc2-[Cl])-[Cl],O=N(=O)c1ccc(Oc2ccc(Cl)cc2Cl)cc1 +2767,SA31c,c1cc(ccc1-[#8]-[#1])-[#6]-[#7]-3-[#6](-c2ccccc2-[#6]-3=[#8])=[#8],[H]Oc1ccc(CN2C(=O)c3ccccc3C2=O)cc1 +2768,SA32a,c1cc(ccc1)-[#8]-[P](=[#8])(-[#8]-[#6])-[#8]-[#6],COP(=O)(OC)Oc1ccccc1 +2769,SA32b,c1cc(ccc1)-[#8]-[P](=[#16])(-[#8]-[#6])-[#8]-[#6],COP(=S)(OC)Oc1ccccc1 +2770,SA34a,[#8](-[#1])-c1ccc(cc1)-[#6]-[#6],[H]Oc1ccc(CC)cc1 +2771,SA34d,[#8](-[#1])-c1ccc(cc1)-[#6](-[#6])(-[#6])-[#6],[H]Oc1ccc(C(C)(C)C)cc1 +2772,SA35,c12ccc3c(c1cccc2)cccc3,c1ccc2c(c1)ccc1ccccc12 +2773,SA37,c1c(cccc1)-[#7]-2-[#6](=[#8])-[#6]-[#6]-[#6]-2=[#8],O=C1CCC(=O)N1c1ccccc1 +2774,SA38,[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1,C1CCCCCCCCCCC1 +2775,SA39,[#6]-[#6]-[#6]-[#6]-[#6]-c1cccc(c1)-[#8]-[#6],CCCCCc1cccc(OC)c1 +2776,SA40,[#6]-[#6]-[#6]-[#6]-[#6]-c1ccc(cc1)-[#8]-[#6],CCCCCc1ccc(OC)cc1 +2777,SA41,c1c(cccc1-[#6](-[F])(-[F])-[F])-[#7](-[#6](=[#8])-[#1])-[#1],[H]C(=O)N([H])c1cccc(C(F)(F)F)c1 +2778,SA43,c1c(cccc1)-[#6]-[#8]-c2ccccc2,c1ccc(COc2ccccc2)cc1 +2779,SA46,[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1=CC2CCC1C2 +2780,SA47,[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2,C1CC2CCC1C2 +2781,SA48,c1(c(cccc1)-[#8]-c2ccccc2)-[Br],Brc1ccccc1Oc1ccccc1 +2782,SA49,c1-2c(cccc1)-[#6]-[#6]-[#6]-2,c1ccc2c(c1)CCC2 +2783,Primary amines (strict),"[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]",C[NH2] +2784,4-chlorobenzene,Clc1ccc([*:1])cc1,Clc1ccc([*:1])cc1 +2785,4-nitrobenzene,[O-][N+](=O)c1cc([*:1])c([*:1])cc1,O=[N+]([O-])c1ccc([*:1])c([*:1])c1 diff --git a/RNN_with_E_Coli_Fine_Tuning_FSR.ipynb b/RNN_with_E_Coli_Fine_Tuning_FSR.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..af14f06ab36822456ca35e041ebfc8e382cdb137 --- /dev/null +++ b/RNN_with_E_Coli_Fine_Tuning_FSR.ipynb @@ -0,0 +1,1677 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "wWSzEAjavzrb", + "outputId": "3c8987e4-5537-46ed-fc4b-0988e03b376c" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "Looking in indexes: https://pypi.org/simple, https://us-python.pkg.dev/colab-wheels/public/simple/\n", + "Requirement already satisfied: bunch in /usr/local/lib/python3.8/dist-packages (1.0.1)\n" + ] + } + ], + "source": [ + "\n", + "pip install bunch" + ] + }, + { + "cell_type": "code", + "source": [ + "from google.colab import drive\n", + "drive.mount('/content/drive')" + ], + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "PXp_V--04b4N", + "outputId": "35b31fa0-1cde-4ddc-b82d-af62805a5c76" + }, + "execution_count": null, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "Drive already mounted at /content/drive; to attempt to forcibly remount, call drive.mount(\"/content/drive\", force_remount=True).\n" + ] + } + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "7mgq8uVbyW4d" + }, + "source": [ + "## Utility Codes" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "oyGzbJOiyau5" + }, + "source": [ + "### Parameter Setting" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "FSYvCcgkvxtK" + }, + "outputs": [], + "source": [ + "import os\n", + "import time\n", + "import json\n", + "from bunch import Bunch\n", + "\n", + "import pandas as pd\n", + "\n", + "df= pd.read_csv('vocab.csv')\n", + "vocab = df['Smiles'].tolist()\n", + "\n", + "def get_config_from_json(json_file):\n", + " with open(json_file, 'r') as config_file:\n", + " config_dict = json.load(config_file)\n", + " config = Bunch(config_dict)\n", + " return config\n", + "\n", + "\n", + "def process_config(json_file):\n", + " config = get_config_from_json(json_file)\n", + " config.config_file = json_file\n", + " config.exp_dir = os.path.join(\n", + " 'experiments', time.strftime('%Y-%m-%d/', time.localtime()),\n", + " config.exp_name)\n", + " config.tensorboard_log_dir = os.path.join(\n", + " 'experiments', time.strftime('%Y-%m-%d/', time.localtime()),\n", + " config.exp_name, 'logs/')\n", + " config.checkpoint_dir = os.path.join(\n", + " 'experiments', time.strftime('%Y-%m-%d/', time.localtime()),\n", + " config.exp_name, 'checkpoints/')\n", + " return config" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "tJp7vxoyyhej" + }, + "source": [ + "### Creating Directory" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "Bx9GeQ9qwEXy" + }, + "outputs": [], + "source": [ + "import os\n", + "import sys\n", + "\n", + "\n", + "def create_dirs(dirs):\n", + " try:\n", + " for dir_ in dirs:\n", + " if not os.path.exists(dir_):\n", + " os.makedirs(dir_)\n", + " except Exception as err:\n", + " print(f'Creating directories error: {err}')\n", + " sys.exit()" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "7ME9uPedQj00" + }, + "source": [ + "## Building Function Vocabulary" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 424 + }, + "id": "5MokMxOEQiaO", + "outputId": "d4eb662d-400e-41f5-ed34-f1278ab6520b" + }, + "outputs": [ + { + "output_type": "execute_result", + "data": { + "text/plain": [ + " Unnamed: 0 Len Functional grp name \\\n", + "0 0 7 Acid anhydrides \n", + "1 1 8 Diacyl peroxides \n", + "2 2 15 Phenyl esters \n", + "3 3 5 Isocyanates \n", + "4 4 8 β-Lactams \n", + "... ... ... ... \n", + "1240 1240 12 SA46 \n", + "1241 1241 11 SA47 \n", + "1242 1242 19 SA48 \n", + "1243 1243 15 SA49 \n", + "1244 1244 6 Primary amines (strict) \n", + "\n", + " SMARTS Smiles \\\n", + "0 [CX3](=[OX1])[OX2][CX3](=[OX1]) O=COC=O \n", + "1 [CX3](=[OX1])[OX2][OX2][CX3](=[OX1]) O=COOC=O \n", + "2 [cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][... CC(=O)Oc1ccccc1 \n", + "3 [NX2]=[CX2]=[OX1] N=C=O \n", + "4 [NX3]1[CX4][CX4][CX3]1(=[OX1]) O=C1CCN1 \n", + "... ... ... \n", + "1240 [#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2 C1=CC2CCC1C2 \n", + "1241 [#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2 C1CC2CCC1C2 \n", + "1242 c1(c(cccc1)-[#8]-c2ccccc2)-[Br] Brc1ccccc1Oc1ccccc1 \n", + "1243 c1-2c(cccc1)-[#6]-[#6]-[#6]-2 c1ccc2c(c1)CCC2 \n", + "1244 [NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])] C[NH2] \n", + "\n", + " Validity \n", + "0 Valid \n", + "1 Valid \n", + "2 Valid \n", + "3 Valid \n", + "4 Valid \n", + "... ... \n", + "1240 Valid \n", + "1241 Valid \n", + "1242 Valid \n", + "1243 Valid \n", + "1244 Valid \n", + "\n", + "[1245 rows x 6 columns]" + ], + "text/html": [ + "\n", + "
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Unnamed: 0LenFunctional grp nameSMARTSSmilesValidity
007Acid anhydrides[CX3](=[OX1])[OX2][CX3](=[OX1])O=COC=OValid
118Diacyl peroxides[CX3](=[OX1])[OX2][OX2][CX3](=[OX1])O=COOC=OValid
2215Phenyl esters[cR1]1([OX2][CX3](=[OX1])[#6])[cR1][cR1][cR1][...CC(=O)Oc1ccccc1Valid
335Isocyanates[NX2]=[CX2]=[OX1]N=C=OValid
448β-Lactams[NX3]1[CX4][CX4][CX3]1(=[OX1])O=C1CCN1Valid
.....................
1240124012SA46[#6]-1-2-[#6]=[#6]-[#6](-[#6]-1)-[#6]-[#6]-2C1=CC2CCC1C2Valid
1241124111SA47[#6]-1-2-[#6]-[#6]-[#6](-[#6]-1)-[#6]-[#6]-2C1CC2CCC1C2Valid
1242124219SA48c1(c(cccc1)-[#8]-c2ccccc2)-[Br]Brc1ccccc1Oc1ccccc1Valid
1243124315SA49c1-2c(cccc1)-[#6]-[#6]-[#6]-2c1ccc2c(c1)CCC2Valid
124412446Primary amines (strict)[NX3H2][CX4&!$([CX4]([NH2])[O,N,S,P])]C[NH2]Valid
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1245 rows × 6 columns

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\n", + " \n", + " \n", + " \n", + "\n", + " \n", + "
\n", + "
\n", + " " + ] + }, + "metadata": {}, + "execution_count": 36 + } + ], + "source": [ + "import pandas as pd\n", + "\n", + "df = pd.read_csv('functions.csv')\n", + "df\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "VpdiNPeLQiNb", + "outputId": "a6cd7530-4f57-4c17-a870-cc846e5d0c16" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "(673, 6)\n" + ] + } + ], + "source": [ + "df_filtered = df[df.Len < 13]\n", + "print(df_filtered.shape)\n", + "vocab = df_filtered['Smiles'].tolist()" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "82goiSvmynck" + }, + "source": [ + "## SMILES TOKENIZER" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "CCJOzUKwuydA" + }, + "outputs": [], + "source": [ + "import numpy as np\n", + "\n", + "\n", + "class SmilesTokenizer(object):\n", + " def __init__(self):\n", + " atoms = [\n", + " 'Al', 'As', 'B', 'Br', 'C', 'Cl', 'F', 'H', 'I', 'K', 'Li', 'N',\n", + " 'Na', 'O', 'P', 'S', 'Se', 'Si', 'Te'\n", + " ]\n", + " special = [\n", + " '(', ')', '[', ']', '=', '#', '%', '0', '1', '2', '3', '4', '5',\n", + " '6', '7', '8', '9', '+', '-', 'se', 'te', 'c', 'n', 'o', 's'\n", + " ]\n", + "\n", + " function = vocab\n", + "\n", + "\n", + "\n", + " padding = ['G', 'A', 'E']\n", + "\n", + " self.table = sorted(function, key=len, reverse=True) + sorted(vocab, key=len, reverse=True) + padding + special\n", + " table_len = len(self.table)\n", + "\n", + " self.table_12_chars = list(filter(lambda x: len(x) == 12, self.table))\n", + " self.table_11_chars = list(filter(lambda x: len(x) == 11, self.table))\n", + " self.table_10_chars = list(filter(lambda x: len(x) == 10, self.table))\n", + " self.table_9_chars = list(filter(lambda x: len(x) == 9, self.table))\n", + " self.table_8_chars = list(filter(lambda x: len(x) == 8, self.table))\n", + " self.table_7_chars = list(filter(lambda x: len(x) == 7, self.table))\n", + " self.table_6_chars = list(filter(lambda x: len(x) == 6, self.table))\n", + " self.table_5_chars = list(filter(lambda x: len(x) == 5, self.table))\n", + " self.table_4_chars = list(filter(lambda x: len(x) == 4, self.table))\n", + " self.table_3_chars = list(filter(lambda x: len(x) == 3, self.table))\n", + " self.table_2_chars = list(filter(lambda x: len(x) == 2, self.table))\n", + " self.table_1_chars = list(filter(lambda x: len(x) == 1, self.table))\n", + "\n", + "\n", + "\n", + " self.one_hot_dict = {}\n", + " for i, symbol in enumerate(self.table):\n", + " vec = np.zeros(table_len, dtype=np.float32)\n", + " vec[i] = 1\n", + " self.one_hot_dict[symbol] = vec\n", + "\n", + " def tokenize(self, smiles):\n", + "\n", + " N = len(smiles)\n", + " token = []\n", + " i = 0\n", + " while (i < N):\n", + " c1 = smiles[i]\n", + " c2 = smiles[i:i + 2]\n", + " c3 = smiles[i:i + 3]\n", + " c4 = smiles[i:i + 4]\n", + " c5 = smiles[i:i + 5]\n", + " c6 = smiles[i:i + 6]\n", + " c7 = smiles[i:i + 7]\n", + " c8 = smiles[i:i + 8]\n", + " c9 = smiles[i:i + 9]\n", + " c10 = smiles[i:i + 10]\n", + " c11 = smiles[i:i + 11]\n", + "\n", + " c12= smiles[i:i + 12]\n", + "\n", + " if c12 in self.table_12_chars:\n", + " token.append(c12)\n", + " i += 12\n", + " continue\n", + "\n", + " if c11 in self.table_11_chars:\n", + " token.append(c11)\n", + " i += 11\n", + " continue\n", + "\n", + " if c10 in self.table_10_chars:\n", + " token.append(c10)\n", + " i += 10\n", + " continue\n", + "\n", + " if c9 in self.table_9_chars:\n", + " token.append(c9)\n", + " i += 9\n", + " continue \n", + " \n", + " if c8 in self.table_8_chars:\n", + " token.append(c8)\n", + " i += 8\n", + " continue\n", + "\n", + " if c7 in self.table_7_chars:\n", + " token.append(c7)\n", + " i += 7\n", + " continue\n", + "\n", + " if c6 in self.table_6_chars:\n", + " token.append(c6)\n", + " i += 6\n", + " continue\n", + "\n", + " if c5 in self.table_5_chars:\n", + " token.append(c5)\n", + " i += 5\n", + " continue\n", + "\n", + " if c4 in self.table_4_chars:\n", + " token.append(c4)\n", + " i += 4\n", + " continue\n", + "\n", + " if c3 in self.table_3_chars:\n", + " token.append(c3)\n", + " i += 3\n", + " continue \n", + "\n", + "\n", + " if c2 in self.table_2_chars:\n", + " token.append(c2)\n", + " i += 2\n", + " continue\n", + "\n", + " if c1 in self.table_1_chars:\n", + " token.append(c1)\n", + " i += 1\n", + " continue\n", + "\n", + "\n", + "\n", + " i += 1\n", + " \n", + " #print(token)\n", + " return token\n", + "\n", + "\n", + "\n", + " def one_hot_encode(self, tokenized_smiles):\n", + " result = np.array(\n", + " [self.one_hot_dict[symbol] for symbol in tokenized_smiles],\n", + " dtype=np.float32)\n", + " result = result.reshape(1, result.shape[0], result.shape[1])\n", + " ##print(result)\n", + " return result\n" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "9D0FvvsmywFk" + }, + "source": [ + "## Data Loader" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "N0m-AmjPufqR" + }, + "outputs": [], + "source": [ + "\n", + "import json\n", + "import os\n", + "import numpy as np\n", + "from tqdm import tqdm\n", + "from tensorflow.keras.utils import Sequence\n", + "#from lstm_chem.utils.smiles_tokenizer2 import SmilesTokenizer\n", + "\n", + "\n", + "class DataLoader(Sequence):\n", + " def __init__(self, config, data_type='train'):\n", + " self.config = config\n", + " self.data_type = data_type\n", + " assert self.data_type in ['train', 'valid', 'finetune']\n", + "\n", + " self.max_len = 0\n", + "\n", + " if self.data_type == 'train':\n", + " self.smiles = self._load(self.config.data_filename)\n", + " elif self.data_type == 'finetune':\n", + " self.smiles = self._load(self.config.finetune_data_filename)\n", + " else:\n", + " pass\n", + "\n", + " self.st = SmilesTokenizer()\n", + " self.one_hot_dict = self.st.one_hot_dict\n", + "\n", + " self.tokenized_smiles = self._tokenize(self.smiles)\n", + "\n", + " if self.data_type in ['train', 'valid']:\n", + " self.idx = np.arange(len(self.tokenized_smiles))\n", + " self.valid_size = int(\n", + " np.ceil(\n", + " len(self.tokenized_smiles) * self.config.validation_split))\n", + " np.random.seed(self.config.seed)\n", + " np.random.shuffle(self.idx)\n", + "\n", + " def _set_data(self):\n", + " if self.data_type == 'train':\n", + " ret = [\n", + " self.tokenized_smiles[self.idx[i]]\n", + " for i in self.idx[self.valid_size:]\n", + " ]\n", + " elif self.data_type == 'valid':\n", + " ret = [\n", + " self.tokenized_smiles[self.idx[i]]\n", + " for i in self.idx[:self.valid_size]\n", + " ]\n", + " else:\n", + " ret = self.tokenized_smiles\n", + " return ret\n", + "\n", + " def _load(self, data_filename):\n", + " length = self.config.data_length\n", + " print('loading SMILES...')\n", + " with open(data_filename) as f:\n", + " smiles = [s.rstrip() for s in f]\n", + " if length != 0:\n", + " smiles = smiles[:length]\n", + " print('done.')\n", + " return smiles\n", + "\n", + " def _tokenize(self, smiles):\n", + " assert isinstance(smiles, list)\n", + " print('tokenizing SMILES...')\n", + " tokenized_smiles = [self.st.tokenize(smi) for smi in tqdm(smiles)]\n", + "\n", + " if self.data_type == 'train':\n", + " for tokenized_smi in tokenized_smiles:\n", + " length = len(tokenized_smi)\n", + " if self.max_len < length:\n", + " self.max_len = length\n", + " self.config.train_smi_max_len = self.max_len\n", + " print('done.')\n", + " return tokenized_smiles\n", + "\n", + " def __len__(self):\n", + " target_tokenized_smiles = self._set_data()\n", + " if self.data_type in ['train', 'valid']:\n", + " ret = int(\n", + " np.ceil(\n", + " len(target_tokenized_smiles) /\n", + " float(self.config.batch_size)))\n", + " else:\n", + " ret = int(\n", + " np.ceil(\n", + " len(target_tokenized_smiles) /\n", + " float(self.config.finetune_batch_size)))\n", + " return ret\n", + "\n", + " def __getitem__(self, idx):\n", + " target_tokenized_smiles = self._set_data()\n", + " if self.data_type in ['train', 'valid']:\n", + " data = target_tokenized_smiles[idx *\n", + " self.config.batch_size:(idx + 1) *\n", + " self.config.batch_size]\n", + " else:\n", + " data = target_tokenized_smiles[idx *\n", + " self.config.finetune_batch_size:\n", + " (idx + 1) *\n", + " self.config.finetune_batch_size]\n", + " data = self._padding(data)\n", + "\n", + " self.X, self.y = [], []\n", + " for tp_smi in data:\n", + " X = [self.one_hot_dict[symbol] for symbol in tp_smi[:-1]]\n", + " self.X.append(X)\n", + " y = [self.one_hot_dict[symbol] for symbol in tp_smi[1:]]\n", + " self.y.append(y)\n", + "\n", + " self.X = np.array(self.X, dtype=np.float32)\n", + " self.y = np.array(self.y, dtype=np.float32)\n", + " \n", + "# return self.X, self.y, [None]\n", + " return self.X, self.y\n", + "\n", + " def _pad(self, tokenized_smi):\n", + " return ['G'] + tokenized_smi + ['E'] + [\n", + " 'A' for _ in range(self.max_len - len(tokenized_smi))\n", + " ]\n", + "\n", + " def _padding(self, data):\n", + " padded_smiles = [self._pad(t_smi) for t_smi in data]\n", + " return padded_smiles" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "NbUu9dy63XKJ" + }, + "source": [ + "## LSTM Model" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "IymzAnUUvG1v" + }, + "outputs": [], + "source": [ + "import os\n", + "import time\n", + "from tensorflow.keras import Sequential\n", + "from tensorflow.keras.models import model_from_json\n", + "from tensorflow.keras.layers import LSTM, Dense\n", + "from tensorflow.keras.initializers import RandomNormal\n", + "\n", + "\n", + "\n", + "class LSTMChem(object):\n", + " def __init__(self, config, session='train'):\n", + " assert session in ['train', 'generate', 'finetune'], \\\n", + " 'one of {train, generate, finetune}'\n", + "\n", + " self.config = config\n", + " self.session = session\n", + " self.model = None\n", + "\n", + " if self.session == 'train':\n", + " self.build_model()\n", + " else:\n", + " self.model = self.load(self.config.model_arch_filename,\n", + " self.config.model_weight_filename)\n", + "\n", + " def build_model(self):\n", + " st = SmilesTokenizer()\n", + " n_table = len(st.table)\n", + " weight_init = RandomNormal(mean=0.0,\n", + " stddev=0.05,\n", + " seed=self.config.seed)\n", + "\n", + " self.model = Sequential()\n", + " self.model.add(\n", + " LSTM(units=self.config.units,\n", + " input_shape=(None, n_table),\n", + " return_sequences=True,\n", + " kernel_initializer=weight_init,\n", + " dropout=0.1))\n", + " self.model.add(\n", + " LSTM(units=self.config.units,\n", + " input_shape=(None, n_table),\n", + " return_sequences=True,\n", + " kernel_initializer=weight_init,\n", + " dropout=0.2))\n", + " self.model.add(\n", + " Dense(units=n_table,\n", + " activation='softmax',\n", + " kernel_initializer=weight_init))\n", + "\n", + " arch = self.model.to_json(indent=2)\n", + " self.config.model_arch_filename = os.path.join(self.config.exp_dir,\n", + " 'model_arch.json')\n", + " with open(self.config.model_arch_filename, 'w') as f:\n", + " f.write(arch)\n", + "\n", + " self.model.compile(optimizer=self.config.optimizer,\n", + " loss='categorical_crossentropy')\n", + "\n", + " def save(self, checkpoint_path):\n", + " assert self.model, 'You have to build the model first.'\n", + "\n", + " print('Saving model ...')\n", + " self.model.save_weights(checkpoint_path)\n", + " print('model saved.')\n", + "\n", + " def load(self, model_arch_file, checkpoint_file):\n", + " print(f'Loading model architecture from {model_arch_file} ...')\n", + " with open(model_arch_file) as f:\n", + " model = model_from_json(f.read())\n", + " print(f'Loading model checkpoint from {checkpoint_file} ...')\n", + " model.load_weights(checkpoint_file)\n", + " print('Loaded the Model.')\n", + " return model" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "GMH8I9iB3uSu" + }, + "source": [ + "## Generator" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "bltRLOMevG9D" + }, + "outputs": [], + "source": [ + "from tqdm import tqdm\n", + "import numpy as np\n", + "#from lstm_chem.utils.smiles_tokenizer2 import SmilesTokenizer\n", + "\n", + "\n", + "class LSTMChemGenerator(object):\n", + " def __init__(self, modeler):\n", + " self.session = modeler.session\n", + " self.model = modeler.model\n", + " self.config = modeler.config\n", + " self.st = SmilesTokenizer()\n", + "\n", + " def _generate(self, sequence):\n", + " while (sequence[-1] != 'E') and (len(self.st.tokenize(sequence)) <=\n", + " self.config.smiles_max_length):\n", + " x = self.st.one_hot_encode(self.st.tokenize(sequence))\n", + " preds = self.model.predict_on_batch(x)[0][-1]\n", + " next_idx = self.sample_with_temp(preds)\n", + " sequence += self.st.table[next_idx]\n", + "\n", + " sequence = sequence[1:].rstrip('E')\n", + "\n", + " return sequence\n", + "\n", + "\n", + " def sample_with_temp(self, preds):\n", + " streched = np.log(preds) / self.config.sampling_temp\n", + " streched_probs = np.exp(streched) / np.sum(np.exp(streched))\n", + " return np.random.choice(range(len(streched)), p=streched_probs)\n", + "\n", + " def sample(self, num=1, start='G'):\n", + " sampled = []\n", + " if self.session == 'generate':\n", + " for _ in tqdm(range(num)):\n", + " sampled.append(self._generate(start))\n", + " return sampled\n", + " else:\n", + " from rdkit import Chem, RDLogger\n", + " RDLogger.DisableLog('rdApp.*')\n", + " while len(sampled) < num:\n", + " sequence = self._generate(start)\n", + " mol = Chem.MolFromSmiles(sequence)\n", + " if mol is not None:\n", + " canon_smiles = Chem.MolToSmiles(mol)\n", + " sampled.append(canon_smiles)\n", + " return sampled" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "PQuZ2lj-2y7g" + }, + "source": [ + "## Fine Tuner" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "XIL7Gx05vG55" + }, + "outputs": [], + "source": [ + "\n", + "\n", + "\n", + "class LSTMChemFinetuner(LSTMChemGenerator):\n", + " def __init__(self, modeler, finetune_data_loader):\n", + " self.session = modeler.session\n", + " self.model = modeler.model\n", + " self.config = modeler.config\n", + " self.finetune_data_loader = finetune_data_loader\n", + " self.st = SmilesTokenizer()\n", + "\n", + " def finetune(self):\n", + " self.model.compile(optimizer=self.config.optimizer,\n", + " loss='categorical_crossentropy')\n", + "\n", + "# history = self.model.fit_generator(\n", + " history = self.model.fit(\n", + " self.finetune_data_loader,\n", + " steps_per_epoch=self.finetune_data_loader.__len__(),\n", + " epochs=self.config.finetune_epochs,\n", + " verbose=self.config.verbose_training,\n", + " use_multiprocessing=True,\n", + " shuffle=True)\n", + " return history\n" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "rPI7-OzS3bWd" + }, + "source": [ + "## Trainer" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "bpmPDt1yvGqT" + }, + "outputs": [], + "source": [ + "from glob import glob\n", + "import os\n", + "from tensorflow.keras.callbacks import ModelCheckpoint, TensorBoard\n", + "\n", + "\n", + "class LSTMChemTrainer(object):\n", + " def __init__(self, modeler, train_data_loader, valid_data_loader):\n", + " self.model = modeler.model\n", + " self.config = modeler.config\n", + " self.train_data_loader = train_data_loader\n", + " self.valid_data_loader = valid_data_loader\n", + " self.callbacks = []\n", + " self.init_callbacks()\n", + "\n", + " def init_callbacks(self):\n", + " self.callbacks.append(\n", + " ModelCheckpoint(\n", + " filepath=os.path.join(\n", + " self.config.checkpoint_dir,\n", + " '%s-{epoch:02d}-{val_loss:.2f}.hdf5' %\n", + " self.config.exp_name),\n", + " monitor=self.config.checkpoint_monitor,\n", + " mode=self.config.checkpoint_mode,\n", + " save_best_only=self.config.checkpoint_save_best_only,\n", + " save_weights_only=self.config.checkpoint_save_weights_only,\n", + " verbose=self.config.checkpoint_verbose,\n", + " ))\n", + " self.callbacks.append(\n", + " TensorBoard(\n", + " log_dir=self.config.tensorboard_log_dir,\n", + " write_graph=self.config.tensorboard_write_graph,\n", + " ))\n", + "\n", + " def train(self):\n", + "# history = self.model.fit_generator(\n", + " history = self.model.fit(\n", + " self.train_data_loader,\n", + " steps_per_epoch=self.train_data_loader.__len__(),\n", + " epochs=self.config.num_epochs,\n", + " verbose=self.config.verbose_training,\n", + " validation_data=self.valid_data_loader,\n", + " validation_steps=self.valid_data_loader.__len__(),\n", + " use_multiprocessing=True,\n", + " shuffle=True,\n", + " callbacks=self.callbacks)\n", + "\n", + " last_weight_file = glob(\n", + " os.path.join(\n", + " f'{self.config.checkpoint_dir}',\n", + " f'{self.config.exp_name}-{self.config.num_epochs:02}*.hdf5')\n", + " )[0]\n", + "\n", + " assert os.path.exists(last_weight_file)\n", + " self.config.model_weight_filename = last_weight_file\n", + "\n", + " with open(os.path.join(self.config.exp_dir, 'config.json'), 'w') as f:\n", + " f.write(self.config.toJSON(indent=2))" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "oUg2HPWy3n8K" + }, + "source": [ + "## Training" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 105 + }, + "id": "NVQQ-UBUvpZf", + "outputId": "5595c9cc-a9d3-4c1d-c937-ad64e5aab838" + }, + "outputs": [ + { + "output_type": "execute_result", + "data": { + "text/plain": [ + "\"\\nfrom copy import copy\\n#from lstm_chem.utils.config import process_config\\n#from lstm_chem.utils.dirs import create_dirs\\n#from lstm_chem.data_loader import DataLoader\\n#from lstm_chem.model import LSTMChem\\n#from lstm_chem.trainer import LSTMChemTrainer\\n\\nCONFIG_FILE = '/content/base_config.json'\\n\\n\\ndef main():\\n config = process_config(CONFIG_FILE)\\n\\n # create the experiments dirs\\n create_dirs(\\n [config.exp_dir, config.tensorboard_log_dir, config.checkpoint_dir])\\n\\n print('Create the data generator.')\\n train_dl = DataLoader(config, data_type='train')\\n valid_dl = copy(train_dl)\\n valid_dl.data_type = 'valid'\\n\\n print('Create the model.')\\n modeler = LSTMChem(config, session='train')\\n\\n print('Create the trainer')\\n trainer = LSTMChemTrainer(modeler, train_dl, valid_dl)\\n\\n print('Start training the model.')\\n trainer.train()\\n\\n\\nif __name__ == '__main__':\\n main()\\n\\n\"" + ], + "application/vnd.google.colaboratory.intrinsic+json": { + "type": "string" + } + }, + "metadata": {}, + "execution_count": 44 + } + ], + "source": [ + "'''\n", + "from copy import copy\n", + "#from lstm_chem.utils.config import process_config\n", + "#from lstm_chem.utils.dirs import create_dirs\n", + "#from lstm_chem.data_loader import DataLoader\n", + "#from lstm_chem.model import LSTMChem\n", + "#from lstm_chem.trainer import LSTMChemTrainer\n", + "\n", + "CONFIG_FILE = '/content/base_config.json'\n", + "\n", + "\n", + "def main():\n", + " config = process_config(CONFIG_FILE)\n", + "\n", + " # create the experiments dirs\n", + " create_dirs(\n", + " [config.exp_dir, config.tensorboard_log_dir, config.checkpoint_dir])\n", + "\n", + " print('Create the data generator.')\n", + " train_dl = DataLoader(config, data_type='train')\n", + " valid_dl = copy(train_dl)\n", + " valid_dl.data_type = 'valid'\n", + "\n", + " print('Create the model.')\n", + " modeler = LSTMChem(config, session='train')\n", + "\n", + " print('Create the trainer')\n", + " trainer = LSTMChemTrainer(modeler, train_dl, valid_dl)\n", + "\n", + " print('Start training the model.')\n", + " trainer.train()\n", + "\n", + "\n", + "if __name__ == '__main__':\n", + " main()\n", + "\n", + "'''" + ] + }, + { + "cell_type": "code", + "source": [], + "metadata": { + "id": "HfusVbkepFFc" + }, + "execution_count": null, + "outputs": [] + }, + { + "cell_type": "code", + "source": [ + " #!zip -r exp.zip experiments/" + ], + "metadata": { + "id": "WYogVr1SYqIH" + }, + "execution_count": null, + "outputs": [] + }, + { + "cell_type": "code", + "source": [ + "#from google.colab import files\n", + "#files.download(\"/content/exp.zip\")" + ], + "metadata": { + "id": "AD3Sb9cUaW4K" + }, + "execution_count": null, + "outputs": [] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "u9o6Sxw14iN1" + }, + "source": [ + "## Fine Tuning" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "jiYkhYlk4wuc", + "colab": { + "base_uri": "https://localhost:8080/" + }, + "outputId": "2f4ee8a0-97ee-4e03-bc23-3cf6f610b067" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "Looking in indexes: https://pypi.org/simple, https://us-python.pkg.dev/colab-wheels/public/simple/\n", + "Requirement already satisfied: rdkit in /usr/local/lib/python3.8/dist-packages (2022.9.5)\n", + "Requirement already satisfied: numpy in /usr/local/lib/python3.8/dist-packages (from rdkit) (1.22.4)\n", + "Requirement already satisfied: Pillow in /usr/local/lib/python3.8/dist-packages (from rdkit) (8.4.0)\n" + ] + } + ], + "source": [ + "pip install rdkit" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "ESaAvgIV4gz8" + }, + "outputs": [], + "source": [ + "import numpy as np\n", + "from sklearn.decomposition import PCA\n", + "import matplotlib.pyplot as plt\n", + "%matplotlib inline\n", + "\n", + "from rdkit import Chem, DataStructs\n", + "from rdkit.Chem import AllChem, Draw\n", + "from rdkit.Chem.Draw import IPythonConsole\n", + "\n", + "#from lstm_chem.utils.config import process_config\n", + "#from lstm_chem.model import LSTMChem\n", + "#from lstm_chem.finetuner import LSTMChemFinetuner\n", + "#from lstm_chem.data_loader import DataLoader" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "RPVwkm9CvpV-", + "colab": { + "base_uri": "https://localhost:8080/" + }, + "outputId": "72b02711-0176-4bef-9ecb-10c3503b271b" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "Loading model architecture from /content/drive/MyDrive/DDP FSR/experiments/2023-02-27/LSTM_Chem/model_arch.json ...\n", + "Loading model checkpoint from /content/drive/MyDrive/DDP FSR/experiments/2023-02-27/LSTM_Chem/checkpoints/LSTM_Chem-04-0.44.hdf5 ...\n", + "Loaded the Model.\n", + "loading SMILES...\n", + "done.\n", + "tokenizing SMILES...\n" + ] + }, + { + "output_type": "stream", + "name": "stderr", + "text": [ + "100%|██████████| 1567/1567 [00:03<00:00, 420.78it/s]\n" + ] + }, + { + "output_type": "stream", + "name": "stdout", + "text": [ + "done.\n", + "Epoch 1/15\n", + "1567/1567 [==============================] - 30s 14ms/step - loss: 1.7070\n", + "Epoch 2/15\n", + "1567/1567 [==============================] - 18s 11ms/step - loss: 1.4273\n", + "Epoch 3/15\n", + "1567/1567 [==============================] - 17s 11ms/step - loss: 1.3239\n", + "Epoch 4/15\n", + "1567/1567 [==============================] - 18s 12ms/step - loss: 1.2488\n", + "Epoch 5/15\n", + "1567/1567 [==============================] - 19s 12ms/step - loss: 1.2020\n", + "Epoch 6/15\n", + "1567/1567 [==============================] - 18s 12ms/step - loss: 1.1559\n", + "Epoch 7/15\n", + "1567/1567 [==============================] - 18s 11ms/step - loss: 1.0998\n", + "Epoch 8/15\n", + "1567/1567 [==============================] - 19s 12ms/step - loss: 1.0606\n", + "Epoch 9/15\n", + "1567/1567 [==============================] - 18s 11ms/step - loss: 1.0335\n", + "Epoch 10/15\n", + "1567/1567 [==============================] - 18s 11ms/step - loss: 0.9963\n", + "Epoch 11/15\n", + "1567/1567 [==============================] - 19s 12ms/step - loss: 0.9668\n", + "Epoch 12/15\n", + "1567/1567 [==============================] - 18s 11ms/step - loss: 0.9427\n", + "Epoch 13/15\n", + "1567/1567 [==============================] - 18s 11ms/step - loss: 0.9174\n", + "Epoch 14/15\n", + "1567/1567 [==============================] - 21s 13ms/step - loss: 0.8950\n", + "Epoch 15/15\n", + "1567/1567 [==============================] - 18s 11ms/step - loss: 0.8713\n" + ] + }, + { + "output_type": "execute_result", + "data": { + "text/plain": [ + "" + ] + }, + "metadata": {}, + "execution_count": 49 + } + ], + "source": [ + "config = process_config('/content/config.json')\n", + "\n", + "modeler = LSTMChem(config, session='finetune')\n", + "finetune_dl = DataLoader(config, data_type='finetune')\n", + "\n", + "finetuner = LSTMChemFinetuner(modeler, finetune_dl)\n", + "finetuner.finetune()" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "CzkqEJsmvpRn" + }, + "outputs": [], + "source": [ + "finetuned_smiles = finetuner.sample(num=100)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "NKkhyY_4-mS4", + "colab": { + "base_uri": "https://localhost:8080/" + }, + "outputId": "e2920866-79b5-4e26-89d5-2dfc696d3f27" + }, + "outputs": [ + { + "output_type": "execute_result", + "data": { + "text/plain": [ + "['Cc1ccc2c(c1)C(C)C(CCCN(C)C)C1=C(C1)N2',\n", + " 'CC(C)(C)C',\n", + " 'CCCCCC',\n", + " 'CN(C)CCON=C1c2ccccc2CCc2ccccc21',\n", + " 'CC(C)(O)C(O)c1ccc(O)cc1',\n", + " 'CCC',\n", + " 'Cc1cc(O)ccc1C=C1[C]2CN(C)C2CC1=O',\n", + " 'CCNc1cccc(C)c1C=Cc1ccccc1',\n", + " 'CC(=O)c1cncn1CC1CCCCC1',\n", + " 'CCCC(C)C1(C)C(=O)NC(=O)NC1=O',\n", + " 'CCN(CC)C(=O)C1CCn2cnc1c2C(C)C',\n", + " 'CC(C)C',\n", + " 'C=C',\n", + " 'NCCc1ccccc1',\n", + " 'CNCCc1ccccn1',\n", + " 'CN(C)CCON1c2ccccc2C=Cc2ccccc21',\n", + " 'CN1C(=O)CC(c2ccccc2)C1=O',\n", + " 'NC1=NC(=O)C1N(C(=O)C1=CC1)c1ccccc1',\n", + " 'Cc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2C',\n", + " 'NC(=O)NO',\n", + " 'NC(=O)Nc1cccc(O)c1O',\n", + " 'CN1C(=O)CCC1Cc1ccccc1',\n", + " 'Cc1ccc2[nH]c(=O)nc(-c3ccccc3)c2c1',\n", + " 'CCN1c2ccccc2Sc2ccccc21',\n", + " 'CC(=C1CCC(=O)NC1=O)c1ccccc1',\n", + " 'COc1ccc2c(c1)N(CC(C)CN(C)C)c1ccccc1S2',\n", + " 'CCOC(=O)Oc1ccccc1C(C)C',\n", + " 'C=C',\n", + " 'CCCC(=O)C(=O)n1c2ccccc3sc3ccc(C)cc21',\n", + " 'NC1OCC(c2ccccc2)=NC1=O',\n", + " 'CCC',\n", + " 'CC1CC(CNC(=O)c2cc(S(C)(=O)=O)ccc2N)N1C',\n", + " 'C=C',\n", + " 'CCc1ccccc1',\n", + " 'CC1CCCCN1',\n", + " 'O=C(O)Oc1cc2ccccc2s1',\n", + " 'CCC(O)CC1(CC)C(=O)NC(=O)NC1=O',\n", + " 'Cc1ccc2c(c1)N(C)CCC(C)C2=O',\n", + " 'CC(C)(C)OC(=O)C(C)(C)c1ccccc1',\n", + " 'CN(CCc1ccccc1)CCn1c(=O)[nH]c2ccccc21',\n", + " 'CC(=O)NC(C)NNC(O)c1ccccc1',\n", + " 'NC1CCCCCN1c1ccccc1',\n", + " 'CCCN1CCN(c2cccc(C)c2C)CC1',\n", + " 'C=C(C)OC(=O)O',\n", + " 'O=C(O)C1CCN(c2ccccc2)C1',\n", + " 'CN(C)CCC(N)N1c2ccccc2Sc2ccccc21',\n", + " 'C[N+](C)(C)CCO',\n", + " 'CCN(CC)CCOC(=O)c1ccc(NC2CCCCC2)cc1',\n", + " 'CCC',\n", + " 'NC(N)=O',\n", + " 'CC(NN)c1ccccc1',\n", + " 'CN1CCN(CCCCOC2c3ccccc3N(C)c3ccccc32)CC1',\n", + " 'COc1cccc(C(O)(O)OC(C)C)c1',\n", + " 'CN(C)CCC=C1c2ccccc2C(C)(C)c2ccccc21',\n", + " 'CC1OC(c2cccc(Br)c2)CN(C)CCN1C',\n", + " 'CCN1N=NNC(=O)C(c2ccccc2)=C1SS',\n", + " 'Cc1cccc(C2=NCC(=O)N(C)c3ccc(C)cc32)c1',\n", + " 'Cc1ccc2c(c1)N(CC(C)CN(C)C)c1ccccc1S2',\n", + " 'CCCCCC',\n", + " 'COC(=O)C1(c2ccccc2)NNC(=O)NC1=O',\n", + " 'CC(C)C',\n", + " 'Cc1ccc(CCN(C)C)cc1O',\n", + " 'CCN1CCCC1CNC(=O)C1=C(C)C(C(O)N(CC)C(=O)OC(C)(C)O)=C1',\n", + " 'CCOC(CC)CC(N)=O',\n", + " 'CNS(=O)(=O)c1ccc2c(c1)N(CCC1CCN(CCOC)CC1)c1ccccc1S2',\n", + " 'CN(C)c1cnccn1',\n", + " 'CCC',\n", + " 'CN1CCCC([C]([C]2CCCC2)c2ccccc2)CC1',\n", + " 'CCC(=O)c1ccc(C)cc1',\n", + " 'C=C',\n", + " 'CC(=O)C1(O)CCCCC1',\n", + " 'CN(C)c1cnccn1',\n", + " 'Cc1ccc2c(c1)N(CCCN(C)C)c1ccccc1S2',\n", + " 'CN1C(=S)CN=C(c2ccccc2)c2ccccc21',\n", + " 'CN(C)CCC(=O)CCn1c2c(ccccc3ccccc31)S2',\n", + " 'CC(N)C(=O)NNC(Br)c1ccncc1',\n", + " 'CN(C)CCCc1c2c(nc3ccc(O)cc13)N2C',\n", + " 'CC(=O)Nc1ccc(C)cc1',\n", + " 'CC(C)C1CCC(=O)OC1(C)C',\n", + " 'C=C',\n", + " 'Cc1cccc(C)c1OCC1CCCN(C)C1',\n", + " 'C=C',\n", + " 'CCCCCCC',\n", + " 'Cc1ccc2c(c1)C(c1ccccc1)=NCC(=O)N2C',\n", + " 'Cc1ccc(C(=O)NCCN2CCN(c3ccccc3)CC2)cc1',\n", + " 'CCn1ccc(=O)c(O)c1C',\n", + " 'CCCCCCC',\n", + " 'CCCCN1CCC(C(C)=O)CC1',\n", + " 'CCN1C(=O)CN=C(CN2CCN(C)CC2)c2cc(Br)ccc21',\n", + " 'CCOC(=O)c1ccc(O)cc1',\n", + " 'CC(O)Cn1c2ccccc2n1C',\n", + " 'CCC1(CC)C(=O)NC(=O)NC1=O',\n", + " 'Cc1ccc2c(c1)C(c1ccccc1)=NCC(=S)N2CC(=O)O',\n", + " 'Cc1ccc2c(c1)N(CC(C)CN(C)C)c1ccccc1S2',\n", + " 'C1CCCCC1',\n", + " 'NC(N)=Nc1nc(-c2ccccc2)cs1',\n", + " 'Cc1cccc(C)c1NC1=NCC=C1',\n", + " 'CN(C(=O)O)c1cc[nH]c(=O)c1-c1ccccc1',\n", + " 'CN(C)CCc1ccccn1',\n", + " 'Cc1cccc(C(=O)C(=O)N(C)C)c1']" + ] + }, + "metadata": {}, + "execution_count": 51 + } + ], + "source": [ + "finetuned_smiles\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "gn4vlKNZ5IYR" + }, + "outputs": [], + "source": [ + "with open('/content/bbbp.txt') as f:\n", + " ksmiles = [l.rstrip() for l in f]\n", + "kmols = [Chem.MolFromSmiles(smi) for smi in ksmiles]\n", + "\n", + "Kfps = []\n", + "for mol in kmols:\n", + " try:\n", + " bv = AllChem.GetMACCSKeysFingerprint(mol)\n", + " fp = np.zeros(len(bv))\n", + " DataStructs.ConvertToNumpyArray(bv, fp)\n", + " Kfps.append(fp)\n", + " except:\n", + " pass\n", + "Klen = len(Kfps)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "1WvcJGzt5SFF" + }, + "outputs": [], + "source": [ + "with open('/content/bbbp.txt') as f:\n", + " fsmiles = [l.rstrip() for l in f]\n", + "fmols = [Chem.MolFromSmiles(smi) for smi in fsmiles]\n", + "\n", + "Ffps, Fbvs = [], []\n", + "for mol in fmols:\n", + " try:\n", + " bv = AllChem.GetMACCSKeysFingerprint(mol)\n", + " Fbvs.append(bv)\n", + " \n", + " fp = np.zeros(len(bv))\n", + " DataStructs.ConvertToNumpyArray(bv, fp)\n", + " Ffps.append(fp)\n", + " except:\n", + " pass\n", + "Flen = len(Ffps)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "ZGRvrTSL5aDL" + }, + "outputs": [], + "source": [ + "Sfps, Sbvs, smols = [], [], []\n", + "for smi in finetuned_smiles:\n", + " mol = Chem.MolFromSmiles(smi)\n", + " smols.append(mol)\n", + " \n", + " bv = AllChem.GetMACCSKeysFingerprint(mol)\n", + " Sbvs.append(bv)\n", + " \n", + " fp = np.zeros(len(bv))\n", + " DataStructs.ConvertToNumpyArray(bv, fp)\n", + " Sfps.append(fp)\n", + "\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "uRgKLu425dkb" + }, + "outputs": [], + "source": [ + "x = Kfps + Ffps + Sfps\n", + "pca = PCA(n_components=2, random_state=71)\n", + "X = pca.fit_transform(x)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "726JRpW35e51", + "colab": { + "base_uri": "https://localhost:8080/", + "height": 334 + }, + "outputId": "203eb081-ca40-499b-edb3-2f048b4f33ff" + }, + "outputs": [ + { + "output_type": "display_data", + "data": { + "text/plain": [ + "
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\n" + }, + "metadata": { + "needs_background": "light" + } + } + ], + "source": [ + "plt.figure(figsize=(8, 5))\n", + "plt.scatter(X[:Klen, 0], X[:Klen, 1],\n", + " c='w', edgecolors='k', label='Known E. Coli inhibitors')\n", + "#plt.scatter(X[Klen:Klen + Flen, 0], X[Klen:Klen + Flen, 1],\n", + "# s=200, c='r', marker='2', edgecolors='k', label='Iteration 4 Molecules')\n", + "plt.scatter(X[Klen + Flen:, 0], X[Klen + Flen:, 1],\n", + " c='b', marker='+', label='Finetuned Generated')\n", + "plt.xlabel('PC 1')\n", + "plt.ylabel('PC 2')\n", + "plt.legend();" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "UhWJHYsJ5jC-" + }, + "outputs": [], + "source": [ + "idxs = []\n", + "for Fbv in Fbvs:\n", + " idx = np.argmax(DataStructs.BulkTanimotoSimilarity(Fbv, Sbvs))\n", + " idxs.append(idx)\n", + "nsmols = [smols[idx] for idx in idxs]" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "RDIXRY0o9yOd" + }, + "outputs": [], + "source": [ + "showmols = []\n", + "for i, j in zip(fmols, nsmols):\n", + " showmols.append(i)\n", + " showmols.append(j)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "-FCC59yc1fiP", + "colab": { + "base_uri": "https://localhost:8080/", + "height": 1000 + }, + "outputId": "2a7697fb-a2d8-4f20-cde2-6387c1d939bd" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stderr", + "text": [ + "/usr/local/lib/python3.8/dist-packages/rdkit/Chem/Draw/IPythonConsole.py:258: UserWarning: Truncating the list of molecules to be displayed to 50. Change the maxMols value to display more.\n", + " warnings.warn(\n" + ] + }, + { + "output_type": "execute_result", + "data": { + "image/png": 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\n", + "text/plain": [ + "" + ] + }, + "metadata": {}, + "execution_count": 67 + } + ], + "source": [ + "\n", + "Draw.MolsToGridImage(showmols, molsPerRow=2)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "aMz-y3NWoYfc" + }, + "outputs": [], + "source": [ + "with open('bbbp_gen_fsr.txt', 'w') as f:\n", + " for line in finetuned_smiles:\n", + " f.write(f\"{line}\\n\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "tclLlv8ot5zX", + "colab": { + "base_uri": "https://localhost:8080/" + }, + "outputId": "ec2dea5d-5c81-435e-998f-3ff0ec70b1f1" + }, + "outputs": [ + { + "output_type": "execute_result", + "data": { + "text/plain": [ + "100" + ] + }, + "metadata": {}, + "execution_count": 69 + } + ], + "source": [ + "len(finetuned_smiles)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "F399xqZfQjF2" + }, + "outputs": [], + "source": [] + } + ], + "metadata": { + "accelerator": "GPU", + "colab": { + "provenance": [] + }, + "gpuClass": "standard", + "kernelspec": { + "display_name": "Python 3", + "name": "python3" + }, + "language_info": { + "name": "python" + } + }, + "nbformat": 4, + "nbformat_minor": 0 +} \ No newline at end of file diff --git a/RNN_with_E_Coli_Fine_Tuning_without_FSR.ipynb b/RNN_with_E_Coli_Fine_Tuning_without_FSR.ipynb new file mode 100644 index 0000000000000000000000000000000000000000..59e5b8bcb96045d85698d412145049102bf26e53 --- /dev/null +++ b/RNN_with_E_Coli_Fine_Tuning_without_FSR.ipynb @@ -0,0 +1,6496 @@ +{ + "cells": [ + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "wWSzEAjavzrb", + "outputId": "2043f30b-da16-4873-9028-b271b8b0ff7a" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "Looking in indexes: https://pypi.org/simple, https://us-python.pkg.dev/colab-wheels/public/simple/\n", + "Collecting bunch\n", + " Downloading bunch-1.0.1.zip (11 kB)\n", + " Preparing metadata (setup.py) ... \u001b[?25l\u001b[?25hdone\n", + "Building wheels for collected packages: bunch\n", + " Building wheel for bunch (setup.py) ... \u001b[?25l\u001b[?25hdone\n", + " Created wheel for bunch: filename=bunch-1.0.1-py3-none-any.whl size=7095 sha256=6510189bb315235f23b782a137190eb162c11472fa824d1b1e16da0924fd98fc\n", + " Stored in directory: /root/.cache/pip/wheels/81/03/84/acbaef8b5bc2ecc1bf944c572037d0fb232a19b19a96579f97\n", + "Successfully built bunch\n", + "Installing collected packages: bunch\n", + "Successfully installed bunch-1.0.1\n" + ] + } + ], + "source": [ + "pip install bunch" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "18SHOfYBFogL", + "outputId": "0ca9022f-4483-47fa-b554-41d080577123" + }, + "outputs": [ + { + "name": "stdout", + "output_type": "stream", + "text": [ + "Mounted at /content/drive\n" + ] + } + ], + "source": [ + "|from google.colab import drive\n", + "drive.mount('/content/drive')" + ] + }, + { + "cell_type": "code", + "source": [ + "selfies" + ], + "metadata": { + "id": "eDFOuc8BZEr9" + }, + "execution_count": null, + "outputs": [] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "8tqzd6vNFucI" + }, + "outputs": [], + "source": [] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "7mgq8uVbyW4d" + }, + "source": [ + "## Utility Codes" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "oyGzbJOiyau5" + }, + "source": [ + "### Parameter Setting" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "FSYvCcgkvxtK" + }, + "outputs": [], + "source": [ + "import os\n", + "import time\n", + "import json\n", + "from bunch import Bunch\n", + "\n", + "import pandas as pd\n", + "\n", + "df= pd.read_csv('vocab.csv')\n", + "vocab = df['Smiles'].tolist()\n", + "\n", + "def get_config_from_json(json_file):\n", + " with open(json_file, 'r') as config_file:\n", + " config_dict = json.load(config_file)\n", + " config = Bunch(config_dict)\n", + " return config\n", + "\n", + "\n", + "def process_config(json_file):\n", + " config = get_config_from_json(json_file)\n", + " config.config_file = json_file\n", + " config.exp_dir = os.path.join(\n", + " 'experiments', time.strftime('%Y-%m-%d/', time.localtime()),\n", + " config.exp_name)\n", + " config.tensorboard_log_dir = os.path.join(\n", + " 'experiments', time.strftime('%Y-%m-%d/', time.localtime()),\n", + " config.exp_name, 'logs/')\n", + " config.checkpoint_dir = os.path.join(\n", + " 'experiments', time.strftime('%Y-%m-%d/', time.localtime()),\n", + " config.exp_name, 'checkpoints/')\n", + " return config" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "tJp7vxoyyhej" + }, + "source": [ + "### Creating Directory" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "Bx9GeQ9qwEXy" + }, + "outputs": [], + "source": [ + "import os\n", + "import sys\n", + "\n", + "\n", + "def create_dirs(dirs):\n", + " try:\n", + " for dir_ in dirs:\n", + " if not os.path.exists(dir_):\n", + " os.makedirs(dir_)\n", + " except Exception as err:\n", + " print(f'Creating directories error: {err}')\n", + " sys.exit()" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "82goiSvmynck" + }, + "source": [ + "## SMILES TOKENIZER" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "CCJOzUKwuydA" + }, + "outputs": [], + "source": [ + "import numpy as np\n", + "\n", + "\n", + "class SmilesTokenizer(object):\n", + "\n", + " def __init__(self):\n", + " atoms = [\n", + " 'Al', 'As', 'B', 'Br', 'C', 'Cl', 'F', 'H', 'I', 'K', 'Li', 'N',\n", + " 'Na', 'O', 'P', 'S', 'Se', 'Si', 'Te'\n", + " ]\n", + " special = [\n", + " '(', ')', '[', ']', '=', '#', '%', '0', '1', '2', '3', '4', '5',\n", + " '6', '7', '8', '9', '+', '-', 'se', 'te', 'c', 'n', 'o', 's'\n", + " ]\n", + "\n", + " function = vocab\n", + "\n", + " padding = ['G', 'A', 'E']\n", + "\n", + " self.table = sorted(atoms, key=len, reverse=True) + special + padding\n", + " table_len = len(self.table)\n", + "\n", + " self.table_2_chars = list(filter(lambda x: len(x) == 2, self.table))\n", + " self.table_1_chars = list(filter(lambda x: len(x) == 1, self.table))\n", + "\n", + " self.one_hot_dict = {}\n", + " for i, symbol in enumerate(self.table):\n", + " vec = np.zeros(table_len, dtype=np.float32)\n", + " vec[i] = 1\n", + " self.one_hot_dict[symbol] = vec\n", + "\n", + " def tokenize(self, smiles):\n", + " smiles = smiles + ' '\n", + " N = len(smiles)\n", + " token = []\n", + " i = 0\n", + " while (i < N):\n", + " c1 = smiles[i]\n", + " c2 = smiles[i:i + 2]\n", + "\n", + " if c2 in self.table_2_chars:\n", + " token.append(c2)\n", + " i += 2\n", + " continue\n", + "\n", + " if c1 in self.table_1_chars:\n", + " token.append(c1)\n", + " i += 1\n", + " continue\n", + "\n", + " i += 1\n", + "\n", + " return token\n", + "\n", + " def one_hot_encode(self, tokenized_smiles):\n", + " result = np.array(\n", + " [self.one_hot_dict[symbol] for symbol in tokenized_smiles],\n", + " dtype=np.float32)\n", + " result = result.reshape(1, result.shape[0], result.shape[1])\n", + " print(result)\n", + " return result" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "9D0FvvsmywFk" + }, + "source": [ + "## Data Loader" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "N0m-AmjPufqR" + }, + "outputs": [], + "source": [ + "import json\n", + "import os\n", + "import numpy as np\n", + "from tqdm import tqdm\n", + "from tensorflow.keras.utils import Sequence\n", + "#from lstm_chem.utils.smiles_tokenizer2 import SmilesTokenizer\n", + "\n", + "\n", + "class DataLoader(Sequence):\n", + " def __init__(self, config, data_type='train'):\n", + " self.config = config\n", + " self.data_type = data_type\n", + " assert self.data_type in ['train', 'valid', 'finetune']\n", + "\n", + " self.max_len = 0\n", + "\n", + " if self.data_type == 'train':\n", + " self.smiles = self._load(self.config.data_filename)\n", + " elif self.data_type == 'finetune':\n", + " self.smiles = self._load(self.config.finetune_data_filename)\n", + " else:\n", + " pass\n", + "\n", + " self.st = SmilesTokenizer()\n", + " self.one_hot_dict = self.st.one_hot_dict\n", + "\n", + " self.tokenized_smiles = self._tokenize(self.smiles)\n", + "\n", + " if self.data_type in ['train', 'valid']:\n", + " self.idx = np.arange(len(self.tokenized_smiles))\n", + " self.valid_size = int(\n", + " np.ceil(\n", + " len(self.tokenized_smiles) * self.config.validation_split))\n", + " np.random.seed(self.config.seed)\n", + " np.random.shuffle(self.idx)\n", + "\n", + " def _set_data(self):\n", + " if self.data_type == 'train':\n", + " ret = [\n", + " self.tokenized_smiles[self.idx[i]]\n", + " for i in self.idx[self.valid_size:]\n", + " ]\n", + " elif self.data_type == 'valid':\n", + " ret = [\n", + " self.tokenized_smiles[self.idx[i]]\n", + " for i in self.idx[:self.valid_size]\n", + " ]\n", + " else:\n", + " ret = self.tokenized_smiles\n", + " return ret\n", + "\n", + " def _load(self, data_filename):\n", + " length = self.config.data_length\n", + " print('loading SMILES...')\n", + " with open(data_filename) as f:\n", + " smiles = [s.rstrip() for s in f]\n", + " if length != 0:\n", + " smiles = smiles[:length]\n", + " print('done.')\n", + " return smiles\n", + "\n", + " def _tokenize(self, smiles):\n", + " assert isinstance(smiles, list)\n", + " print('tokenizing SMILES...')\n", + " tokenized_smiles = [self.st.tokenize(smi) for smi in tqdm(smiles)]\n", + "\n", + " if self.data_type == 'train':\n", + " for tokenized_smi in tokenized_smiles:\n", + " length = len(tokenized_smi)\n", + " if self.max_len < length:\n", + " self.max_len = length\n", + " self.config.train_smi_max_len = self.max_len\n", + " print('done.')\n", + " return tokenized_smiles\n", + "\n", + " def __len__(self):\n", + " target_tokenized_smiles = self._set_data()\n", + " if self.data_type in ['train', 'valid']:\n", + " ret = int(\n", + " np.ceil(\n", + " len(target_tokenized_smiles) /\n", + " float(self.config.batch_size)))\n", + " else:\n", + " ret = int(\n", + " np.ceil(\n", + " len(target_tokenized_smiles) /\n", + " float(self.config.finetune_batch_size)))\n", + " return ret\n", + "\n", + " def __getitem__(self, idx):\n", + " target_tokenized_smiles = self._set_data()\n", + " if self.data_type in ['train', 'valid']:\n", + " data = target_tokenized_smiles[idx *\n", + " self.config.batch_size:(idx + 1) *\n", + " self.config.batch_size]\n", + " else:\n", + " data = target_tokenized_smiles[idx *\n", + " self.config.finetune_batch_size:\n", + " (idx + 1) *\n", + " self.config.finetune_batch_size]\n", + " data = self._padding(data)\n", + "\n", + " self.X, self.y = [], []\n", + " for tp_smi in data:\n", + " X = [self.one_hot_dict[symbol] for symbol in tp_smi[:-1]]\n", + " self.X.append(X)\n", + " y = [self.one_hot_dict[symbol] for symbol in tp_smi[1:]]\n", + " self.y.append(y)\n", + "\n", + " self.X = np.array(self.X, dtype=np.float32)\n", + " self.y = np.array(self.y, dtype=np.float32)\n", + "\n", + "# return self.X, self.y, [None]\n", + " return self.X, self.y\n", + "\n", + " def _pad(self, tokenized_smi):\n", + " return ['G'] + tokenized_smi + ['E'] + [\n", + " 'A' for _ in range(self.max_len - len(tokenized_smi))\n", + " ]\n", + "\n", + " def _padding(self, data):\n", + " padded_smiles = [self._pad(t_smi) for t_smi in data]\n", + " return padded_smiles" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "NbUu9dy63XKJ" + }, + "source": [ + "## LSTM Model" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "IymzAnUUvG1v" + }, + "outputs": [], + "source": [ + "import os\n", + "import time\n", + "from tensorflow.keras import Sequential\n", + "from tensorflow.keras.models import model_from_json\n", + "from tensorflow.keras.layers import LSTM, Dense\n", + "from tensorflow.keras.initializers import RandomNormal\n", + "\n", + "\n", + "\n", + "class LSTMChem(object):\n", + " def __init__(self, config, session='train'):\n", + " assert session in ['train', 'generate', 'finetune'], \\\n", + " 'one of {train, generate, finetune}'\n", + "\n", + " self.config = config\n", + " self.session = session\n", + " self.model = None\n", + "\n", + " if self.session == 'train':\n", + " self.build_model()\n", + " else:\n", + " self.model = self.load(self.config.model_arch_filename,\n", + " self.config.model_weight_filename)\n", + "\n", + " def build_model(self):\n", + " st = SmilesTokenizer()\n", + " n_table = len(st.table)\n", + " weight_init = RandomNormal(mean=0.0,\n", + " stddev=0.05,\n", + " seed=self.config.seed)\n", + "\n", + " self.model = Sequential()\n", + " self.model.add(\n", + " LSTM(units=self.config.units,\n", + " input_shape=(None, n_table),\n", + " return_sequences=True,\n", + " kernel_initializer=weight_init,\n", + " dropout=0.3))\n", + " self.model.add(\n", + " LSTM(units=self.config.units,\n", + " input_shape=(None, n_table),\n", + " return_sequences=True,\n", + " kernel_initializer=weight_init,\n", + " dropout=0.5))\n", + " self.model.add(\n", + " Dense(units=n_table,\n", + " activation='softmax',\n", + " kernel_initializer=weight_init))\n", + "\n", + " arch = self.model.to_json(indent=2)\n", + " self.config.model_arch_filename = os.path.join(self.config.exp_dir,\n", + " 'model_arch.json')\n", + " with open(self.config.model_arch_filename, 'w') as f:\n", + " f.write(arch)\n", + "\n", + " self.model.compile(optimizer=self.config.optimizer,\n", + " loss='categorical_crossentropy')\n", + "\n", + " def save(self, checkpoint_path):\n", + " assert self.model, 'You have to build the model first.'\n", + "\n", + " print('Saving model ...')\n", + " self.model.save_weights(checkpoint_path)\n", + " print('model saved.')\n", + "\n", + " def load(self, model_arch_file, checkpoint_file):\n", + " print(f'Loading model architecture from {model_arch_file} ...')\n", + " with open(model_arch_file) as f:\n", + " model = model_from_json(f.read())\n", + " print(f'Loading model checkpoint from {checkpoint_file} ...')\n", + " model.load_weights(checkpoint_file)\n", + " print('Loaded the Model.')\n", + " return model" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "GMH8I9iB3uSu" + }, + "source": [ + "## Generator" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "bltRLOMevG9D" + }, + "outputs": [], + "source": [ + "from tqdm import tqdm\n", + "import numpy as np\n", + "#from lstm_chem.utils.smiles_tokenizer2 import SmilesTokenizer\n", + "\n", + "\n", + "class LSTMChemGenerator(object):\n", + " def __init__(self, modeler):\n", + " self.session = modeler.session\n", + " self.model = modeler.model\n", + " self.config = modeler.config\n", + " self.st = SmilesTokenizer()\n", + "\n", + " def _generate(self, sequence):\n", + " while (sequence[-1] != 'E') and (len(self.st.tokenize(sequence)) <=\n", + " self.config.smiles_max_length):\n", + " x = self.st.one_hot_encode(self.st.tokenize(sequence))\n", + " preds = self.model.predict_on_batch(x)[0][-1]\n", + " next_idx = self.sample_with_temp(preds)\n", + " sequence += self.st.table[next_idx]\n", + "\n", + " sequence = sequence[1:].rstrip('E')\n", + " return sequence\n", + "\n", + " def sample_with_temp(self, preds):\n", + " streched = np.log(preds) / self.config.sampling_temp\n", + " streched_probs = np.exp(streched) / np.sum(np.exp(streched))\n", + " return np.random.choice(range(len(streched)), p=streched_probs)\n", + "\n", + " def sample(self, num=1, start='G'):\n", + " sampled = []\n", + " if self.session == 'generate':\n", + " for _ in tqdm(range(num)):\n", + " sampled.append(self._generate(start))\n", + " return sampled\n", + " else:\n", + " from rdkit import Chem, RDLogger\n", + " RDLogger.DisableLog('rdApp.*')\n", + " while len(sampled) < num:\n", + " sequence = self._generate(start)\n", + " mol = Chem.MolFromSmiles(sequence)\n", + " if mol is not None:\n", + " canon_smiles = Chem.MolToSmiles(mol)\n", + " sampled.append(canon_smiles)\n", + " return sampled" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "PQuZ2lj-2y7g" + }, + "source": [ + "## Fine Tuner" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "XIL7Gx05vG55" + }, + "outputs": [], + "source": [ + "\n", + "\n", + "\n", + "class LSTMChemFinetuner(LSTMChemGenerator):\n", + " def __init__(self, modeler, finetune_data_loader):\n", + " self.session = modeler.session\n", + " self.model = modeler.model\n", + " self.config = modeler.config\n", + " self.finetune_data_loader = finetune_data_loader\n", + " self.st = SmilesTokenizer()\n", + "\n", + " def finetune(self):\n", + " self.model.compile(optimizer=self.config.optimizer,\n", + " loss='categorical_crossentropy')\n", + "\n", + "# history = self.model.fit_generator(\n", + " history = self.model.fit(\n", + " self.finetune_data_loader,\n", + " steps_per_epoch=self.finetune_data_loader.__len__(),\n", + " epochs=self.config.finetune_epochs,\n", + " verbose=self.config.verbose_training,\n", + " use_multiprocessing=True,\n", + " shuffle=True)\n", + " return history\n" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "rPI7-OzS3bWd" + }, + "source": [ + "## Trainer" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "bpmPDt1yvGqT" + }, + "outputs": [], + "source": [ + "from glob import glob\n", + "import os\n", + "from tensorflow.keras.callbacks import ModelCheckpoint, TensorBoard\n", + "\n", + "\n", + "class LSTMChemTrainer(object):\n", + " def __init__(self, modeler, train_data_loader, valid_data_loader):\n", + " self.model = modeler.model\n", + " self.config = modeler.config\n", + " self.train_data_loader = train_data_loader\n", + " self.valid_data_loader = valid_data_loader\n", + " self.callbacks = []\n", + " self.init_callbacks()\n", + "\n", + " def init_callbacks(self):\n", + " self.callbacks.append(\n", + " ModelCheckpoint(\n", + " filepath=os.path.join(\n", + " self.config.checkpoint_dir,\n", + " '%s-{epoch:02d}-{val_loss:.2f}.hdf5' %\n", + " self.config.exp_name),\n", + " monitor=self.config.checkpoint_monitor,\n", + " mode=self.config.checkpoint_mode,\n", + " save_best_only=self.config.checkpoint_save_best_only,\n", + " save_weights_only=self.config.checkpoint_save_weights_only,\n", + " verbose=self.config.checkpoint_verbose,\n", + " ))\n", + " self.callbacks.append(\n", + " TensorBoard(\n", + " log_dir=self.config.tensorboard_log_dir,\n", + " write_graph=self.config.tensorboard_write_graph,\n", + " ))\n", + "\n", + " def train(self):\n", + "# history = self.model.fit_generator(\n", + " history = self.model.fit(\n", + " self.train_data_loader,\n", + " steps_per_epoch=self.train_data_loader.__len__(),\n", + " epochs=self.config.num_epochs,\n", + " verbose=self.config.verbose_training,\n", + " validation_data=self.valid_data_loader,\n", + " validation_steps=self.valid_data_loader.__len__(),\n", + " use_multiprocessing=True,\n", + " shuffle=True,\n", + " callbacks=self.callbacks)\n", + "\n", + " last_weight_file = glob(\n", + " os.path.join(\n", + " f'{self.config.checkpoint_dir}',\n", + " f'{self.config.exp_name}-{self.config.num_epochs:02}*.hdf5')\n", + " )[0]\n", + "\n", + " assert os.path.exists(last_weight_file)\n", + " self.config.model_weight_filename = last_weight_file\n", + "\n", + " with open(os.path.join(self.config.exp_dir, 'config.json'), 'w') as f:\n", + " f.write(self.config.toJSON(indent=2))" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "oUg2HPWy3n8K" + }, + "source": [ + "## Training" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 380 + }, + "id": "NVQQ-UBUvpZf", + "outputId": "6bfd4d30-7e63-4a69-cdb2-ac962d992ca7" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "Create the data generator.\n", + "loading SMILES...\n" + ] + }, + { + "output_type": "error", + "ename": "FileNotFoundError", + "evalue": "ignored", + "traceback": [ + "\u001b[0;31m---------------------------------------------------------------------------\u001b[0m", + "\u001b[0;31mFileNotFoundError\u001b[0m Traceback (most recent call last)", + "\u001b[0;32m\u001b[0m in \u001b[0;36m\u001b[0;34m\u001b[0m\n\u001b[1;32m 32\u001b[0m \u001b[0;34m\u001b[0m\u001b[0m\n\u001b[1;32m 33\u001b[0m \u001b[0;32mif\u001b[0m \u001b[0m__name__\u001b[0m \u001b[0;34m==\u001b[0m \u001b[0;34m'__main__'\u001b[0m\u001b[0;34m:\u001b[0m\u001b[0;34m\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[0;32m---> 34\u001b[0;31m \u001b[0mmain\u001b[0m\u001b[0;34m(\u001b[0m\u001b[0;34m)\u001b[0m\u001b[0;34m\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[0m", + "\u001b[0;32m\u001b[0m in \u001b[0;36mmain\u001b[0;34m()\u001b[0m\n\u001b[1;32m 17\u001b[0m \u001b[0;34m\u001b[0m\u001b[0m\n\u001b[1;32m 18\u001b[0m \u001b[0mprint\u001b[0m\u001b[0;34m(\u001b[0m\u001b[0;34m'Create the data generator.'\u001b[0m\u001b[0;34m)\u001b[0m\u001b[0;34m\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[0;32m---> 19\u001b[0;31m \u001b[0mtrain_dl\u001b[0m \u001b[0;34m=\u001b[0m \u001b[0mDataLoader\u001b[0m\u001b[0;34m(\u001b[0m\u001b[0mconfig\u001b[0m\u001b[0;34m,\u001b[0m \u001b[0mdata_type\u001b[0m\u001b[0;34m=\u001b[0m\u001b[0;34m'train'\u001b[0m\u001b[0;34m)\u001b[0m\u001b[0;34m\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[0m\u001b[1;32m 20\u001b[0m \u001b[0mvalid_dl\u001b[0m \u001b[0;34m=\u001b[0m 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\u001b[0;36m_load\u001b[0;34m(self, data_filename)\u001b[0m\n\u001b[1;32m 53\u001b[0m \u001b[0mlength\u001b[0m \u001b[0;34m=\u001b[0m \u001b[0mself\u001b[0m\u001b[0;34m.\u001b[0m\u001b[0mconfig\u001b[0m\u001b[0;34m.\u001b[0m\u001b[0mdata_length\u001b[0m\u001b[0;34m\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[1;32m 54\u001b[0m \u001b[0mprint\u001b[0m\u001b[0;34m(\u001b[0m\u001b[0;34m'loading SMILES...'\u001b[0m\u001b[0;34m)\u001b[0m\u001b[0;34m\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[0;32m---> 55\u001b[0;31m \u001b[0;32mwith\u001b[0m \u001b[0mopen\u001b[0m\u001b[0;34m(\u001b[0m\u001b[0mdata_filename\u001b[0m\u001b[0;34m)\u001b[0m \u001b[0;32mas\u001b[0m \u001b[0mf\u001b[0m\u001b[0;34m:\u001b[0m\u001b[0;34m\u001b[0m\u001b[0;34m\u001b[0m\u001b[0m\n\u001b[0m\u001b[1;32m 56\u001b[0m \u001b[0msmiles\u001b[0m \u001b[0;34m=\u001b[0m \u001b[0;34m[\u001b[0m\u001b[0ms\u001b[0m\u001b[0;34m.\u001b[0m\u001b[0mrstrip\u001b[0m\u001b[0;34m(\u001b[0m\u001b[0;34m)\u001b[0m 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[config.exp_dir, config.tensorboard_log_dir, config.checkpoint_dir])\n", + "\n", + " print('Create the data generator.')\n", + " train_dl = DataLoader(config, data_type='train')\n", + " valid_dl = copy(train_dl)\n", + " valid_dl.data_type = 'valid'\n", + "\n", + " print('Create the model.')\n", + " modeler = LSTMChem(config, session='train')\n", + "\n", + " print('Create the trainer')\n", + " trainer = LSTMChemTrainer(modeler, train_dl, valid_dl)\n", + "\n", + " print('Start training the model.')\n", + " trainer.train()\n", + "\n", + "\n", + "if __name__ == '__main__':\n", + " main()" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "WYogVr1SYqIH" + }, + "outputs": [], + "source": [ + "\n", + "!zip -r exp.zip experiments/" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "AD3Sb9cUaW4K" + }, + "outputs": [], + "source": [ + "from google.colab import files\n", + "files.download(\"/content/exp.zip\")" + ] + }, + { + "cell_type": "markdown", + "metadata": { + "id": "u9o6Sxw14iN1" + }, + "source": [ + "## Fine Tuning" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "jiYkhYlk4wuc", + "outputId": "66e4cfa3-3770-4eff-99fe-7f38444e1ee5" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "Looking in indexes: https://pypi.org/simple, https://us-python.pkg.dev/colab-wheels/public/simple/\n", + "Collecting rdkit\n", + " Downloading rdkit-2022.9.5-cp38-cp38-manylinux_2_17_x86_64.manylinux2014_x86_64.whl (29.4 MB)\n", + "\u001b[2K \u001b[90m━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━━\u001b[0m \u001b[32m29.4/29.4 MB\u001b[0m \u001b[31m38.3 MB/s\u001b[0m eta \u001b[36m0:00:00\u001b[0m\n", + "\u001b[?25hRequirement already satisfied: numpy in /usr/local/lib/python3.8/dist-packages (from rdkit) (1.22.4)\n", + "Requirement already satisfied: Pillow in /usr/local/lib/python3.8/dist-packages (from rdkit) (8.4.0)\n", + "Installing collected packages: rdkit\n", + "Successfully installed rdkit-2022.9.5\n" + ] + } + ], + "source": [ + "pip install rdkit" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "ESaAvgIV4gz8" + }, + "outputs": [], + "source": [ + "import numpy as np\n", + "from sklearn.decomposition import PCA\n", + "import matplotlib.pyplot as plt\n", + "%matplotlib inline\n", + "\n", + "from rdkit import Chem, DataStructs\n", + "from rdkit.Chem import AllChem, Draw\n", + "from rdkit.Chem.Draw import IPythonConsole\n", + "\n", + "#from lstm_chem.utils.config import process_config\n", + "#from lstm_chem.model import LSTMChem\n", + "#from lstm_chem.finetuner import LSTMChemFinetuner\n", + "#from lstm_chem.data_loader import DataLoader" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "RPVwkm9CvpV-", + "outputId": "7b107b41-902b-4907-9d81-a9a460a17c6b" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stdout", + "text": [ + "Loading model architecture from /content/LSTM_Chem/experiments/2020-03-24/LSTM_Chem/model_arch.json ...\n", + "Loading model checkpoint from /content/LSTM_Chem/experiments/2020-03-24/LSTM_Chem/checkpoints/LSTM_Chem-22-0.45.hdf5 ...\n", + "Loaded the Model.\n", + "loading SMILES...\n", + "done.\n", + "tokenizing SMILES...\n" + ] + }, + { + "output_type": "stream", + "name": "stderr", + "text": [ + "100%|██████████| 1567/1567 [00:00<00:00, 32948.53it/s]" + ] + }, + { + "output_type": "stream", + "name": "stdout", + "text": [ + "done.\n", + "Epoch 1/15\n" + ] + }, + { + "output_type": "stream", + "name": "stderr", + "text": [ + "\n" + ] + }, + { + "output_type": "stream", + "name": "stdout", + "text": [ + "1567/1567 [==============================] - 20s 10ms/step - loss: 1.5729\n", + "Epoch 2/15\n", + "1567/1567 [==============================] - 15s 10ms/step - loss: 1.3931\n", + "Epoch 3/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.3388\n", + "Epoch 4/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.2836\n", + "Epoch 5/15\n", + "1567/1567 [==============================] - 15s 10ms/step - loss: 1.2557\n", + "Epoch 6/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.2298\n", + "Epoch 7/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.2174\n", + "Epoch 8/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.1929\n", + "Epoch 9/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.1726\n", + "Epoch 10/15\n", + "1567/1567 [==============================] - 17s 11ms/step - loss: 1.1627\n", + "Epoch 11/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.1446\n", + "Epoch 12/15\n", + "1567/1567 [==============================] - 15s 10ms/step - loss: 1.1349\n", + "Epoch 13/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.1216\n", + "Epoch 14/15\n", + "1567/1567 [==============================] - 16s 10ms/step - loss: 1.1056\n", + "Epoch 15/15\n", + "1567/1567 [==============================] - 15s 10ms/step - loss: 1.1026\n" + ] + }, + { + "output_type": "execute_result", + "data": { + "text/plain": [ + "" + ] + }, + "metadata": {}, + "execution_count": 34 + } + ], + "source": [ + "config = process_config('/content/config.json')\n", + "\n", + "modeler = LSTMChem(config, session='finetune')\n", + "finetune_dl = DataLoader(config, data_type='finetune')\n", + "\n", + "finetuner = LSTMChemFinetuner(modeler, finetune_dl)\n", + "finetuner.finetune()" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "CzkqEJsmvpRn", + "outputId": "9fc050c2-09e3-464a-d722-ad1064b3b943" + }, + "outputs": [ + { + 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'Cc1cnc2c(c1)C(c1ccccc1)=NCC(=O)N2',\n", + " 'CCc1ccc(CNC2=NC(=O)CC2)cc1',\n", + " 'CC(=O)C1c2ccccc2Oc2ccccc21',\n", + " 'C=CC1(CCCN(C)C)c2ccccc2C1c1ccccc1',\n", + " 'NCCc1ccccc1',\n", + " 'CN(C)CCCN1c2ccccc2C=Cc2ccccc21',\n", + " 'NC(Cl)(Cl)Br',\n", + " 'CCCN',\n", + " 'CC(N)=O',\n", + " 'O=C(c1cccnc1)N1CCOCC1',\n", + " 'CCc1ccccc1',\n", + " 'CCCC(=O)C1=CC=CNC1C(N)=O',\n", + " 'CN1CCN(C(=O)c2cccnc2)CC1',\n", + " 'CN(C)CCCC1C2=C(C=CC=Cc3ccccc31)C2',\n", + " 'CCNC1=NC2C=C(O)C=CC(Cc3ccc(Cl)cc31)C2',\n", + " 'CN(C)CCC(c1ccccc1)c1ccccc1',\n", + " 'Cc1ncsc1CCCl',\n", + " 'CCCC1CC(=O)NC1C',\n", + " 'CN(C)CCN1C2=NC=CC=Cc3ccc(Cl)cc3C21',\n", + " 'Cc1ccc(OCC2C(O)C2CC(C)C)cc1',\n", + " 'CN(C)CCOC(c1ccccc1)c1ccccc1',\n", + " 'CCC1(CC)C(=O)NC(=O)OC1=O',\n", + " 'C1CCCCC1',\n", + " 'CN(C)CCC1C2=C(C=CC=Cc3ccc(Cl)cc31)S2',\n", + " 'C=CCC1CCN(C(O)c2ccccc2)CC1',\n", + " 'Cc1csc(N=C(N)N)n1',\n", + " 'CCC(=O)Oc1ccc2c(c1)N(CCCN1CCN(CCO)CC1)c1ccccc1S2',\n", + " 'CN(C)CC=C1c2ccccc2C=Cc2ccccc21',\n", + " 'CCC(=O)O',\n", + " 'OC=NC1=C(c2ccccc2)CNC1',\n", + " 'CCC',\n", + " 'CCC(C)CC',\n", + " 'CN(C)CCCN1c2ccccc2Sc2ccccc21',\n", + " 'CCCCn1nc(N)nc1C(=O)O',\n", + " 'CCNCCCCc1cccnc1',\n", + " 'CCC(F)(F)C(F)(F)F',\n", + " 'O=C(O)Oc1ccccc1',\n", + " 'CCO',\n", + " 'CC(=O)C=CC(c1ccccc1)c1ccc(Cl)cc1',\n", + " 'CCCOC(N)=O',\n", + " 'CC1C(=O)CN=C(c2ccccc2Cl)c2cc(Cl)ccc21',\n", + " 'CCN',\n", + " 'CC(C)CCO',\n", + " 'CCN1CCN(CCCC2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1',\n", + " 'CNC(C)C',\n", + " 'CC(C)(C=O)CO',\n", + " 'CC(O)C(F)(F)F',\n", + " 'CCc1ccccc1',\n", + " 'FC(F)(F)CCl',\n", + " 'CN(C)CCC1c2ccccc2Sc2ccccc21',\n", + " 'FC(F)(F)CC1(C(F)(F)Cl)CO1',\n", + " 'CCCCO',\n", + " 'C=CC(N)C1=CN=C(C)C1=O',\n", + " 'C#CCC',\n", + " 'Cc1ccccc1-n1ccc(C)c1CC1CCCCC1',\n", + " 'CC(C)CCOc1ccccc1',\n", + " 'C=C',\n", + " 'C=NCc1scnc1C',\n", + " 'C=CCC1(CC(C)C)C(=O)NC(=O)NC1=O',\n", + " 'CCNc1nccs1',\n", + " 'C=CCC1(CC)C(=O)NC(=O)NC1=S',\n", + " 'CCCC1C(=O)CC(c2ccccc2)C1=O',\n", + " 'CC1(C)CC(c2ccccc2)c2cc(O)c(C(=O)O)cc21',\n", + " 'CC(=O)C(c1ccccc1)c1ccccc1',\n", + " 'CC1C2=C(C=Cc3ccccc31)C(=O)OC2(C)C',\n", + " 'CCCCCC(=O)NO',\n", + " 'CCC1(O)C(=O)OC(=O)N(C)C1=O',\n", + " 'C1CC1',\n", + " 'ON1CCCOC(c2ccccc2)C1',\n", + " 'NNCC=C1c2ccccc2Sc2ccccc21',\n", + " 'CN(C)CC=C1c2ccccc2Sc2ccccc21',\n", + " 'COC1CCN(C)CCc2ccc(Cl)cc2N1c1ccccc1',\n", + " 'CN(C)CCC=C1c2ccccc2Sc2ccc(C(N)=O)cc21',\n", + " 'COCCCC(c1ccccc1)c1ccccc1',\n", + " 'CN1C(=O)CN=C(Br)c2cc(Cl)ccc21',\n", + " 'CC(C)OCC(=O)O',\n", + " 'C=CCCC(=O)C(C)c1ccccc1',\n", + " 'CC1C=NNC1=O',\n", + " 'CNc1c(C)cccc1Cl',\n", + " 'CC1CCCC1',\n", + " 'CC(C)CO',\n", + " 'C#CCNC(O)c1cccc(Br)c1',\n", + " 'FC(F)(F)C1=CC=CC=CC2CCN=CC12',\n", + " 'O=C1C2=CC=CC=CCCCC3CCC(CCC23)OC1C(F)(F)F',\n", + " 'CC(=O)N1C(=O)OC1Cc1ccccc1',\n", + " 'Cc1ccccc1',\n", + " 'CC1CCCC1',\n", + " 'OCCN1CCN(CCC2c3ccccc3Sc3ccc(Cl)cc32)CC1',\n", + " 'CCC1=CC=C(C)C1',\n", + " 'CC1(C)Cc2ccccc2N(N)c2ccccc21',\n", + " 'C=C(N)N(C)Cc1ccccc1',\n", + " 'CC(Cc1ccccc1)OC(=O)O',\n", + " 'CC(C)C(=O)CC(c1ccccc1)c1ccccc1',\n", + " 'CC(F)(F)Cl',\n", + " 'O=C(NCC(O)c1ccccc1O)c1ccccc1C=Cc1ccc(Br)cc1']" + ] + }, + "metadata": {}, + "execution_count": 36 + } + ], + "source": [ + "finetuned_smiles" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "gn4vlKNZ5IYR" + }, + "outputs": [], + "source": [ + "with open('/content/bbbp.txt') as f:\n", + " ksmiles = [l.rstrip() for l in f]\n", + "kmols = [Chem.MolFromSmiles(smi) for smi in ksmiles]\n", + "\n", + "Kfps = []\n", + "for mol in kmols:\n", + " try:\n", + " bv = AllChem.GetMACCSKeysFingerprint(mol)\n", + " fp = np.zeros(len(bv))\n", + " DataStructs.ConvertToNumpyArray(bv, fp)\n", + " Kfps.append(fp)\n", + " except:\n", + " pass \n", + "\n", + "Klen = len(Kfps)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "1WvcJGzt5SFF" + }, + "outputs": [], + "source": [ + "with open('/content/bbbp.txt') as f:\n", + " fsmiles = [l.rstrip() for l in f]\n", + "fmols = [Chem.MolFromSmiles(smi) for smi in fsmiles]\n", + "\n", + "Ffps, Fbvs = [], []\n", + "for mol in fmols:\n", + " try:\n", + "\n", + " bv = AllChem.GetMACCSKeysFingerprint(mol)\n", + " Fbvs.append(bv)\n", + " \n", + " fp = np.zeros(len(bv))\n", + " DataStructs.ConvertToNumpyArray(bv, fp)\n", + " Ffps.append(fp)\n", + " except:\n", + " pass\n", + "\n", + "Flen = len(Ffps)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "ZGRvrTSL5aDL" + }, + "outputs": [], + "source": [ + "Sfps, Sbvs, smols = [], [], []\n", + "\n", + "#with open('/content/bbbp_gen.txt') as f:\n", + " # finetuned_smiles = [l.rstrip() for l in f]\n", + "#fmols = [Chem.MolFromSmiles(smi) for smi in fsmiles]\n", + "\n", + "for smi in finetuned_smiles:\n", + " mol = Chem.MolFromSmiles(smi)\n", + " smols.append(mol)\n", + " \n", + " bv = AllChem.GetMACCSKeysFingerprint(mol)\n", + " Sbvs.append(bv)\n", + " \n", + " fp = np.zeros(len(bv))\n", + " DataStructs.ConvertToNumpyArray(bv, fp)\n", + " Sfps.append(fp)\n", + "\n" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "uRgKLu425dkb" + }, + "outputs": [], + "source": [ + "x = Kfps + Ffps + Sfps\n", + "pca = PCA(n_components=2, random_state=71)\n", + "X = pca.fit_transform(x)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 337 + }, + "id": "726JRpW35e51", + "outputId": "9cff27e1-2181-49eb-88f1-c24221f42868" + }, + "outputs": [ + { + "output_type": "display_data", + "data": { + "text/plain": [ + "
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QKBS0Fo9MJtMxlQIZnQUmcEZXoJNynDsdplxl1zmMar5txyEXRLPnQWwk3Hw+H+gaJicPY3//Puzp6cF8Ph+40hvAzzCTOVlH4JnMSfQ8z+oyyOfzSotHLpfDUqkUeD5YG18ZYAJndAW4paIZInnpyCfIHEZl8bAdhyqhxXGe8fFxHB4edjq23DCkWCw2kH+lUsGBgQGtRk7CyhJxL323sLCAxWKxwe8va/Ymi0eY55wJfGWACZzRFWANXA+RvKrVKhaLRfQ8D7PZbJ15PGieeD6fx1QqhZ7nYaFQiLRIiWy2btYFYTJNu5jB5f1lYUcniExOHq6Lttf5wOUAQXlMpnsT5DnniPSVBSZwRlegk33grYJuMaZFPqqIb5fjNBtMGDXRmPz+LuOT95cJVUew/f376sZdq9UwlUo1zA1p0bq5pQA4XXS76xwzga8sMIEzugYycZTL5Y6LSo8TusWYyMdFw3Zpo2qLYo9SkIqKYHRjls3XrvvXarU6N4RM8JTvryLKsKlirjn8LnBNiVtJ789yBBM4oyuhIpJcLof5fL4jFqIoNR+bVkWkYPNxu5Kv6TguQkIQYoiKaEzX5mKCVu2fTqd9N0Q6na67bsr3V90T01haFcvhkgq30i1aywFM4IyuRLMaV9xoJYHTYqwKvAqTc23aTiQgkVhTqZRfTSzqdpuux7OZr13OJfr9xTz5SqWCIyMjRh+4fCyV0BE0DiEuDdmlkA9r550PJnBGV8KkybQzuM3VBxlmgTQJBUQ+uVxOS3au2p+JNG3+9qCpWzYEDV5sJtjRJiyootCDCmpRxSE0C9OzwNp594AJnNGVMC3UcaaX2XzILgQedoFs1twchfZn0/ZTqZTVjB+sOErwFqlx9VOP6rlymYO4NeSwfnpGZ4EJnNGVcPV5RmkKLJfLDWbUkZERZSCYiWzbtUBGmdtN+ckiKOo7ygC4MHNluuem32zCQitJLG4NOayfnk3rnQUmcEbXolarYaFQQM/zsFgsYrVarVuIog50M/WClmEi8HYWpYlqATblXdvM7/I+NjKOypxrO5YtF7uVZmRbXnsUAmBQP30+n2fTeoeBCZzR9Qi6EIUNdDNpnUEQ1QLczhxfExmKglUqlfIFprCCS1ChI+jzkEql/LRE11rxcUNOY1tYOF1ZTvccRiUA6u5toVBg03qHgQmcsWwRdaBbEA3chKi0yjAEHta8HORY7SSAsKZh2i7O2gJB71c+n8disVg3FnreWjGP8jxwOePOAxM4Y9lCjJimxahYLGI+nw+18ATxgdsQhCzlbSl1KWi1LZ1WF3X6VztNsLbgrEqlUjeX9Le4XVwISuCm6nLZbLbuGlphyubgts4DEzhj2aJWq+Hw8LCStMSFOwhcKplFCRWxJhJ7cXLycGAC12nAUfpVEe0BWHEGQZnObRPA4tImZ2ex7n719+/DycnD1v1UAkepVMLR0dEGM3+Uz6Ep9ZF94J0FJnBG18NECjrSymazXbHwyMRKFcCmpqYaqn/ZiNHkw4/SPNoqTU2+ZhKu5DlwTY+KS5ukjmtE4DMzRzCR2Gt9/kSBQ2xSMzY2Vrdv1OO21RvgKPTOARM4o6tRLpeN5sRu99vpanD39PT4C225XG7QylSaUSqV0gZxDQwMYKVSafgtDDG0QlNTnWNkZMSvnEbnFJ8HFx942Oh2E6mR4CASo8vcii4gUye0pZrsi4HHLYMboXQfmMAZXQOVxqUiLtE83u1+O3nxF82ws7NLc5LNZp2uUdUnfHx83E+/UxFgWNKNW1Nzua8U8EXn1lljKAo9zBhdhCcSHERClIVIlWvG1qSGnoGZmSPY37/Pebw6FxATePehIwkcADYCwCIAPAgADwDAB2z7MIEvb6i0EBNxBW3gEXZMJpKam5vDdDrtN8OYm5sLdY6JiQmcmTlS1/1qw4aHsL9/n1/728XKUC6Xsbd3NyYS9/i587IpNpPJdIV51OWa5b91Akw+nzeeyxRt7yI82YQNsiJRxHmxWMRsNotDQ0O4sNDYpEbuhOZKuK5BmEzc3YNOJfBRADjn1P/XAcBDAHCWaR8m8OUN1SJoWsQLhYL/nWoBbjYYzSYYDAzcj319dzUslmFJnMbf378PN2x4yD93kA5hExMTOD7+CK5efbfRH97JxE1QXbNcq1wOVOzp6cFqtVr3LFSrVaM7xXSf6Tg2QcJ0jNlZxJ6eO5WCRX9/v7JsrdwJzZXAXdMgmcC7Bx1J4A0DAfgqAFxh2oYJfHlDtVDqiCubzRq1qijSwWyk2dt7J87MHGn4PZ1OO59DhdnZJfM5nVv0+8uRySIR9/fvq1v0E4l7lOMrFotd4V6QSVHVLUwWmMK4U0z7uApPNF6VFk8ErjPtFwoFHBwcVDapIR+4K+FGVYiI0TnoeAIHgAIA/BgA0qbtmMCXN3Qal7ywjY6O4vz8vLF5RhQFWXSaF8Ci1o8YZLF0rdlNRCamG2Wz2QZhBGCxzuxKkdEyKdg00ijRrKYnzpHcrxux8Z6GcaeYNGxX4UkF2d+8deuJurkQ68rrCsyI5O0yj1EVImJ0DjqawAEgBQD3AcBvaH6/HgD2A8D+8fHxmKaI0QnQLb6Dg4PKalX0f9U+UWgitsAiFYG7auBBa3bXajU/xUjnu6Z9iMhpPyIF6ufdygC/KEy1NFd07eJzoLqnQYPrTBq2q/CkGnN//z4EWKxLLRPnYmFhwXcDRXVPoixExOgMdCyBA0AfAHwLAP5fl+1ZA28t2pEPqjqnzUepWnxdtDXbGDzPM0YfN+MDt5llw2iStI/OdE7nbEVhjiiinek+pFIprFQq2myEZrVL21yHKT8rHm9m5giuXn03ZjKZBh84HSvKIjitLkTEiBcdSeAA4AFAFQA+4boPE3jr0GkVmXQLm6kUZRhNRL7uUqmkjTKfnV0i8TBR6K6BUUEX81qthvl8Xul28DwPC4UC5vN56zGb1ZybJXDxPpj80JlMJhKCUs01jblZjZ4C0kZHR31iVWUH2MrQcoGVlYlOJfBLAQAB4HsAcODU51+Z9mECbx26JbfaNM4wmoh4PF0hEd1xgpzPNO6ozM5BLBkyoopSDnsccX5MkeAqs3pUoPKoUfrUEcM1gqnVlkoGi2low8PDdYFyHFW+PNGRBB7mwwTeOnRLdbOoLQXidetIVmWyDep7tKUdyYtxEO1Lt62LUBZ1oY+wpnPKfSdBTJeLTd9HaSWS50Dluw4b1S5eo1ywSI7bECvy2fLbmcCXL5jAGYHRLRo4YrSmRfG6TVqffK4w0b/yuHUdyIIIKSZNzUUoa3elLtW1JhJ7cWDg/gYBaXR0NLLSsCJcosfD5pWbttflglMcgOr56um5kyurLXMwgTMCo9N84K2CeN06IaZYLDbMSRRR7zryDCJMmTS1IMeJMv0riFClGuNSY5B7cHh4GAuFgn9Mcc7laHsXP78Ncj4+wUVIEMdDbhVb9oCuIt9Sl7PFwCmNjOUBJnBGKHRK0EyrxyFGocvBYGLkMOLpxTzK/Ft5EXbxqYq50iqtlFLIWuEDb0b4E69VFmjIQkGQiU++T1T/PazgGdYHHnQe5Jx/Of1sdhZxzZq9yueL0tBc7lenvM+MYGACZ3Qtgqb4TE9PN12bXIQYmJZKpbBardb9TkQaZf6tvBjb8pQTib04M3NESxKiJaAVi3gz7hdxX5s5X2d6ls+nOncUMQVBrkU1Ltt2VG+AxqCyrLgGsa1Ui9pyABM4o2vhUmRDJk2x2xblZUdBXLYFOa78W1sevC3IStTUbOeJgtybCYDU+cAnJw9rt9e5L+h84v+b1aqDwDQP4lwXCgUcHh5uGI9scWjm/rjUHWDtvDPBBM7oWtjKXNo0nIWFpaIuUSzYKnIZGxvDNWvWYCqVQs/zIstLVp1blacsm1pnZ0/PD9UPz2QyVqEiSg1NdV/kJiRBNF6ZyFzOp9PAm/FrB4VuXKp8b4pTiItAbcIEa+edCyZwRtfCtDi7tpuketOqYwSFSC6jo6OYTCYbTJs607mLlhNEEyIykgmcfO8qH75ubKaUuaCkIhOCqglJlH3Iy+Wy1QcuR/gHjSwPO86g+d5xwfQedVPGyUoEE3iXgs1a5vzqIBo4tZgkTVSsDR4WAwMDWv+rHLxGi7mppnYYTcjkA9cF1qXTaWMgFUHU5IOSrhyFHaUApZqjcrmMhULBj1VIJpPKqmphc7vDQvUOx1VjwbRemJ6tbqn5sFLBBN6FWA5mLZWmFDRwiLRIMX2ISFBF7tlsFsfGxvwc6Gw2i2vXrsXx8XFlV6lm5pTywV3Sx2jcpq5WYTWhycnD2N+/r2FeTb5h+bqpzrjp3C5jiZuwdHNUKBSc7q3KB76Upra3Ze9WHBqvy3qhI3jWwDsbTOBdiG5/qZoxo5oWI5HYBwYGsFQq+YtSPp9vaHixYcMGHBoa8ufOFBAX1NoRRAN38dlHrQmZNF/RPD44OIjZbNZ3BVSrVb/zWaFQ8OcibAGTKE3GJoHJ5Ryq+ub9/fu0QXJxIA7hvJn1olXphYxwYALvQsRh1mqlSV5eUIIsMGG1LN1+qVSqzhwsghb/MAsqlfh08YG7+OyDLsK2+6myUNB1iRXlqHNbraZuhEL72AghSNBWlAFy4j0WYXtf2ll1Lup3sdn1wnU8TOCtBxN4F0JeqGo1ez9oE6KU+l1ednlBCbLAhNWybPuZArXCai/lchn7+/uNUehkttXV8xZTeYKYQbPZbF3KnOp+lstlTKfTDfdqYeF0RTnR1K6bo2Kx2FQTj6gISzdH+Xw+8D1sd9nYKBG3xS6OueIYHzcwgXchxIWqWq02aHkUuOP6AkT1grsKAnFo4CYt69ixY1pzNmnuOh943EE8tNiVy2W/frcpkC1MIBJdq2o+VfuJRUBEAcYkBNkW2Fa5fVRz1IyA2s3ETYg7ZiZqAl8OMT6tAhN4l4IWKl0jgyCdmKIiKZN5Wx571D5wnZZFvlxVHXCd71xc/KMmHjomwGJDmteGDQ81+OldFy6TBYHM4rr7KZKeXFFONLW3ypcaB8Km6akqvIXVDNupVbbi3FEJO90e49NKMIF3OVzJ1/QCRPXCBNHQoohCpzSkSqXSVKStCVG7F+hYW7eewJmZI3UE3kwREdNzIKao2aAKKiuVSn4JWp0P3AWdbBZ1fX7kbXK5HObzeeu1tFuAaQWiInBOXXMHE3iXw5V8bRpYFIuLyUcal/RMY69UKpjP531/89DQUGSLY1DiCZKSMzNzBPv79yFicwuX6Tkgi4yrwGKqq93JJNwMXN4j0/MtN7IJc3wZy8F8HwasgbuDCbzLoSJfsReyrK3qFpkoFuZarabU0KrVaqzS8/T0NGYymbpc8LDNQpqFSRhSEfRSa8hFRLQvXKoFXTT/68zvZAUJYnVQPQs2H3xYi0onwEV4Mm2jchUFPb6MlUrgK8FaERWYwJcBVIvnxMQElkqlhkV9dHTUmdjCkHo+n8disVi3T5zSs05ooPrarYaJhPv79+HMzBHlb4j2hUvXcUuMJdBFldO4ojD/q2IIoiyP2g4t3yY81Wo1Y6aAqkBPkOOLWE4R8GGxXC09UYMJfJmiXC5jJpPRBrjF5bMLs18YjY9gWhhNC2pcMGlak5OHMZHYG9hPr1vQVddeqVSMgXBhhSnTPNuyCmZnl1wFzQS7hdHog5CA7bzk/9cFQi4sLGVCBD2+akwmAmdiY4hgAl+moJdcRya2RhTNRhxHsXC6LHi2a4wKrtdk8nPTgrz0/0XnBVi3oJuCBol05HPozLY287ip9Kotr392dslVQOc1nSuMUKJCFIKk6hkcHh7G0dFR9DwPi8Wi3xSFOoaZEJR8bRYXNi0zmMCXKWzlOWmRDUOMMprRCnRjdC2gotu/mdadzSycqm2pZ3WzJtHZWcRkcp8fEZ5Op7FUKvnnpXuQTqedG7rYrq9Wq+Hw8DBms1mtaV6ngcuCB5UlNc2l6rkLI0xGEQhlOkatdrp4UrFYxOHh4ciJVH5OOLiLIYMJfJmCgrl0/mFahORFX9y/2cXfBSYtUve9rUhHLpfDubm5ujG6CBi0HeVo03ZB/fq686lqbavGIwcekia9Zs3d2Nd3V921joyM4JYtWxrmYGRkBOfm5pzujen6dPnzVPiG7oGoIZMPfGbmyKkgvaXVhBqriMVq6Dnt799X5xYQ50DOTadnwRQAFkUqki1ojTTxVpmybRaXqN0KjM4HE3iXw+Q/npiYQM/z6rQnWnhV5kExcttGzGL0c7FYrFsIgmgFQTVwKvEpa4km868LidVqp1tvEuEkEntxw4aHIousV3W7Us2r6vdKpVIX0yALX5R1IM+hi7Bguj5doSC57SiRiByF7nleXUMQXW15gEVfuBkeHjamstEYbBq4SlCIQgNPpVJtIT+TUB2XW4HR2WAC72K4kCwVOhE1OvpbR5zi8U3Cge68QTSdID5wOTXMRVBwtSRMTU35faDFvtCrVu1W7j82NhZpMBiRrRipThq77PZwWYhdNTPdeCh332QJsfmuFxaWmpWIPv9169bVbUcBbqJ7Yc2avc7Cmw6mXvEuqNVqfg9x0dfdTsKz3fdWuBUYnQUm8C6Gywspv/Rk3jSZ4xCXFkAy3w4MDAQyry8smHNiZegEBeroJVsPgggKrqZUcTsiTpspP4yP3VYxDWARt2490TAOMabB5b67ama26nm6dp+yAEOaM5nii8UiptPpBk1ank8KcJMD/KrVat0zUa1WG9wnMmTXQ1iy0rllXCquqcaisgqFNWOLli/XAEUCVzhbfmAC72K4vpCq6FpqEymCNEGd9jI4OIg9PT0N5tJa7XStbTJ35vP5pvNXXQQFmURoXGS2DaKB03ai5msy5evOLZqQXaqxLSws+Jo3EVkmU28JIN9xLpcz3vegmpluPCSAqUzs4+PjDS6EWq2xgtvIyEiDaV/XVCaRuMcvJZvJZPza9uI5TVHeMunGVdXOBbagwDirHrIGvrLQsQQOAJ8GgJ8CwEGX7VcigTfzQppMjKb88fn5eW1gHPkGaXHXEXitVqsre1ooFJQaiknLkBdF6lVN7gGARezt3a0M5FJpUyZTvs0HrrNy6BZwVVDY5OThOk00mTxW54t/1av+CbPZrB99rro/FJ0u+pzFOQvjDkHUB7mJ9QRcn8Vqtaqcz02bnvIr0ulIXqy2JxOefP5m3o1mNVXTuW3jChJwGSZNjn3gywudTOBbAeAcJnA9mn0hVWbyWk2f80vb6chj7dq16HkeJhL34OrVd2sLUYhBStVq1U/HKRQK2tzbQqHgm2YTiYS/uNEcFItFrFQqmEjsxfHxR/xz9/buxoGB+63+zFqthoODgz4Jiq08bVHoQciDrl+XliVaDgAWcdWq3Q1lUlUCwvj4OA4PD2M+n/d9+eK5s9msHxWuunZboJsqD1sMCnMlvYWFBUwmk8b5NB2Lxim3WlUF0YV9N5rVVE3jV/1WrVZ9YTZIvrso6FJdh0wmg4lEQikYi/twFPryQMcS+NLYoMAEboar6dYVU1NTWg2IyF63OI2Pj2M2m8VXveqfcM0aNYFPTU1hLpfzSVtV6lU0u6o0VjEimRZbut7x8UcwkdhbZ35evfoubbtRkVR157EJSuKibBKARD+27piTk4f9ubJVXCNhg4SvmZkjuGbN6Wunjmc0p+J9CGo61blNyC+tE+xUbW2p97luPnXPn3ys0dFR//6ojlcqlXxiKxQKmM/nnd6LZgLgarX6kquyX15+DsXnO4zgoHqOyMUhvyuM5Qcm8GUE8WUWNdsgRU16enqwWq0qzc6ksesWmYWFJd8wbUO5vSLElpQuC5ZtGyJPkVwWFhYayCqVShlJVUcaLqZNmZRNx5LJnr5LpVKBA81knzeZoYnAARZx9eq7safnzrrv5cpoLtDdB4oM17kNdAKlKBBks1msVCr+ftlstsEHrvKn28zSZOIPaqmigElx3K4paGKwJf2rspTQd+KzEsZ0HzROhLG80NUEDgDXA8B+ANg/Pj4ezwx1AURTWrFYdErB0hGSSEb0e7FYxP7+flxYWMArrrhC2xOaFhvSQCm3V4QoANgWLJs2K4+XzNLHjh2rI3DSFE2kGmTxVFk9ROJWEQZpi3EFHxGZTk1N1RWMmZiYUBZUca1NLl6zioxEgs7lckY/te6aZC21XC7XxUhkMhntc7AkmCw6PSOm+RPRjA+c9jUFihYKBf96xesK82zYxspR5ssbXU3g4melauCqhVXXNYlyvMNEydKiSoFiqlrqsgauWnjEBcekOZH24qIZ03jn5+e1AXiFQkF7XeQaMBWkEYUklbm2XC7XLcaydr127Vrr3Ae5x7q871qt5lc8k6+Jcq7HxsaUPngXX7h4TfPz81pLjc2NE2QeZLO0eH/E6HX5NxefOsVGpFIpP7CxGR847StbW+TzytvTdVIxIddngzXwlQ0m8C6H6gW25XiHjYSVF5uxsbEGjSybzWKpVNIuPGJesUlYICHAZaEXxzs4OGiMALcFOqn8h+IYwkYYi53R5PFSdLmcby9C3CeZTOLY2Fjd/RF94r29u3F8/JGG6yfTOVkjxCBBVYMOXcU6uh4StESoGo/oSo4GCaiam5urs/ws+ftPx1mYiM8kKKrM27rnwsWHTs+K6M5RPQ/y9nSu8fFHsLd3t3MMC/vAVzY6lsABYBcAPAUAxwHgCQC4zrT9ciNw2ayoq6qlImvdwkEaeFgTobxfrVbD9evX+xoMRaFPTU3VBWOJGBoaqgsWq1QqdQSmCwxz8RWL43LRJHVlQlOplB/BW6vV6qwNJuGILBSy8EDkKsMWLKW6DlVQXz6fryOjmZkjmEjsbYhup9z2YrFYNxemFpkmslGRvIm0XDRKFei8W7Zs8U30PT13nvL5Y12ddboPlLWgE9TkYEkaJ7khxLkvFAp1fmvbddAzo/KBkytF3v50rMLp63GtoSCO1RaFzlhe6FgCD/pZTgSuWyjFOuYiuau0IJlIRGIIayKU96PFXwz4ofQeWlBVwUuqKlvkh9ady3WMNohz6+KDd3VP0HgTiUSdH5iCu6anpxvGogsIJEFGpVXqKqMVi0Vl9y+q5AawiDMzRzCXy9U1BjHNs2iWt21LsM1pmHtI56X5mp1F32wuBysmk0mtVUd85mztUVXnN123DHp2VO+GaltVHX4xl5/BUIEJvANh02Jk0x9F6IoL1tzcnLYUqoqYxFxrV78l5V6L383MHMHe3t0NqUy0iOq0XlVlM7k4ispv28zc6qKNKchI5Re39aYmEhFbfqrIGxGN+fZTU1PKfG4T8cgEDrCImUx9rXEyrxNMhEv3ha7PJRrelEIlBjoGAR2frl1sCiPmto+MjPj3RoSKbHXvmPwc2ubIBFcXgTgWuf49g2ECE3gHwrZQqopjqILKTBAXF13LSJ3fWIyglRfC2VnEROKehhxwGmMul8PBwcFT2yxisVjEwcFB7O/v1wZVBS1wIUKuBifOrc6ETdHDqnMRkZDZX57vIASl08BXrdrdkPZFmrRJABKvmaLMZ2aOYF/fXXV58X19d/klWVUWhSUT/D0NpnSTa0Y2V6vMx3LxF1fQeXt7d9cJI5OThzGRuKdOSHUlW5XrYHx8HNevX9/wXKksT5SiGeZ9k/cRxyzXvw8SJxAEcR2X0VowgbcZqhfJpoHLC6Bs9nWJABa30ZllxchtMa9c9FmrNMKenh7cuvVEHXES8c3Pz9f1il5YWCqRSUFZxWLRNzXafNXyPKiuXSZwUevWRZ6LZCifa2HhdCvNZs38ogBBloqRkRHcsOGhU009GoWgZDKp9IFT9D1ZQfr67vItAKoiLmNjY75lQxZi+vruwtWr764TWohMVD5d8rdSkJfok5fnRiy/6go676pVu+sC1yiQbWhoyN82yD2hssEUw5HL5XB4eFjpoxbfA52waxu/bh/dmHWZE0HmT1XOWDWeVprsWXiIDkzgbYQpClunveiCb+hFMKWHib440eRuMuUuLDRGgovm7Ewmg6VSqW7fYrGoNP8uBdjc06BFrVlzd4MmlEwm/cAhF61KHiMFcskkqNK6ZQ1bpfnQXBBhme5fkAWJIu6pbKoYwKbygff09Gg7dclm++Hh4Tqzs5wXT+OktEAag0pwIAI0PUdi9LMtfz8oarWaHz8htidVNVVxvSdByJ5iOlyFySDn0Y3ZVD3QFSoCV42HGubEjSjeGcZpMIHHBBcp0/Rii+ZjsWSmqjkHvQBhJXnyZcu+YKpeJh5X9QJSbrjoT1elmA0ODvrtMsVAK+p/LY45lUr5mrDLQqsy5ct9pnVlSWUNe2xsTHmN+XzeF6JkM39YbUL2W4sLrioQ0NV3S24RXR69uL3oQ5+cPOyPZdOmp3wTtRzRbJtHU/6+a5aALo3RVhLW9Z6YBEP5GBQVHsYf7iqAymMO63tHND9XKpN9mOj3MGjWasWoBxN4DHCVMsNEQY+Pj+PQ0FBD8QnT8UxVyBDRN2uL5xkZGfG1Dbn4iorsScggk/TQ0JDfsEIslEL+ZVo4TGM2zYM8n7rjACz6zUHIb28K2hoZGcFkMmkleduC40oipoVWd1xbdzRE9O+dbu5oe5U/d3LyMK5efbe24p5pvmkMqq5jo6OjRgGUri9IkSHX/GwVdGSSz+f985BrwyZwNqOBR70fovm5UgXNtSr6vRmhhNEIJvAY4Pri2bYzaVtBfGmmOuAUdKbaj/yDoj/T8zzlAktESf5Bz/NwaGiormVopVLBTCaD4+Pjvg9cp6mNjY35wgBZIlSBY7QA6fz4a9bsxURirz9e3fnS6TTm83kslUqYSqUaCEGMDrflo4cxE9qIWzy2rZsX3ScytYvdqmjcZJnRtTa1VTdzsWRQkRpR0DO5gFyOq3oebMVnTHOpysYQx0waaX3g3N5A99bleVAJfLLvXeza53qNQX3gcWvDrIFHCybwGBAkEtb0YrschzQGnV9yZGTE14RE0EuzpF3oa0nTwksaui5yurf3TpycPIzDw8N+TWxVlG+lUqkbbz6fxw0bNtRtl8/ncf369ZhOp42dyBDRN/vquomZuj/J8QVyownxftjSx+jYYnCcGLFfLBYxn89rnxkTgYuL+8DAgF/pTtZuxbHIBXPk+RgdHcVEIqF9LsJah8QKYDqhSmVGp7gC03nFZ8a1+IwN4jhMx11y+yw27OOq9Zv2sVkddAWCXM6re65qtVqdoEqCStzaMPvAowUTeAxQSZm6+uG6F7tW09d/JtM51XFWmSpJ66pUKsqXZim1aLEuolcOOqNxISKWSiXfTC5rwKJPm1pa2jpyiajVasqa1DoCyOfzfiCTeF7RVE6EqSKEarWK6XS6Yc7JuiGfjyLjdVYKnXlXzs/P5XKhI7DlBU9VmESEXLKWtk2n09jf34+VSsVKljZNSTxuJpPxU9OKxSIODw8b3SM6AUR3XhJMRQFJnEsam46Amo1JmZk5gj09d4aKc7AhrCWuWa21XdowR6FHBybwGKCK2jZFPqtAmq+KFObn5516CNMCWqvVfFIngpT7Zvf13dUQ8UwLpklqloPFqKWljRxs80cLtfyCk29V7rC1adNTDWlrJiJyjZImwjFF6lMRHNtiGGRxpDlwiXpWHVe89zq/senYUURz66w1ui5duvOOjo4qrQ6q7AHVXOiOKT9fpmdWtC40qzGqrA+mZzEuvzFrw90PJvCYIJs9g0q64gIsv+zigmkjSl1BDTI3UlBOMpk8VUFtsW4/k1ZE309MTOCGDQ/hqlW7sVgs+h+TxqqbM5u5UD4uCRC63G3dImUqSar6zhSPQL5J2yLruuiKYzbdX5MpnywGpntnW8CbjebWxUu4mOdNz7x8HfR/sWqcCJfn16b9q7T9MNAJE83EBajO4arhsjbc3WACbwHCpJGYNDo5Kty0QOtMv+SHBlj0m0D09e3BNWv2NvjSTQs0mTJnZxE3bHjID55av359gz8xl8vh3Nyc8nrn5ubqgpJUC6ZKc9Z12NIREV3Xpk1PKfPPZR84aasqV4UYza3TZkW3iWsVMvGemrRb3aIrBoyp7l2z/lzTeOmYJNTIjUVsAqHu+KZ3iJ4tMSNDbBNrE64WFhb8QjTyPZZrx8v7qmCaU5OQYHp+XTVleVu5sQ1jeYEJvAWwLVi6aFhdAJd4PJ2J1GQWFFN8qtWqX9ZUTDkR/ck6k6dcqU3MO67VanVR6OvWrasrUiK7GExatxgBbqoap4oeJ4hmeSpasnr13b7vnfYRF1850jyfzyujv8nfbvOBiw1lTBDvWRgzJ12PWIlNRNRFO+RoaVOlsjBBWbZ4EPl+y8V6bD3l6fmi8YvR3kGLqdjul0uQnun5tQla8lojltVlLD8wgbcAtpdaR/BitHahUPAXMXmRFCujUW3xZDLpL+DysUWSnZiYaPAni8UcarWaVpgol8s+ARJR0DFNXZjk61Vdvxj0VywWMZlM+uORo8FzuZxfY121yNGYSqWSss64KWVKXDgLhQKuX79eqbWLEcMktIyNjYUyvZo0WlsKkWp+SJCQc5p1KUZhNHKxLKnOgiITfZC0qHK5rOwzrhKIRJcVCaO6iHx6vnK5XN0xXN0MMtoVkEYgAUHV2CbOAi2M9oAJvEUwLYyuQSpiHrIYha6r533s2DEslUoNAXRkUtRJ69SNq6enB5PJJI6NjdXlEpOQIC9sGzduNJqbdVqI/Ldq0RQjuEWyIMFlbGxMa4acmpry50EWVjZseMjvbCXvqyppayqkY1vsVfdU9VzYArlswY86E+1ScOGdWgIPG9RUq+l7iovX3awvl9wscnyHPD7RZE7XWK1WfQtNJpNpEMQ2btxYdxyTT940HzYNu5nGPC6gOZYJnFrLMpYXQhM4AGwCgDcAQEr6/k2m/eL6dDqBE2SNjghPJOFareaTpthfWmUOtZE/LXSiz5TM0PK+sj9ZZw6lxVC1GOdyOaV/lsYg1+yem5tz0siJxAi6PGdZkBHL0KqElYGBgYb7YvPVFgoF5b11CbQSycpEmCSkyGRl86Ob4hXoPDq/aNDrDXrdQYLXCoVCQzwCWRJs4xsYGPDTIsU0w1WrdiOivuiPOK9htWIXH3dUrXFV6CQfOAfIxY9QBA4AvwsA/wwAtwLAYwDwVuG37+j2i/PTDQSu81eLxS/m5+d9v5uKQGW/qq0qlxjNTseqVqs4MjKi9Q0ODw8jYv1iJAeCqQKDVOUzdZoskdHIyAieccYZdVYCEwlREJxLepWs+eiEFR108QM6X7spc0C2IsjzK1+D6TdTAJVLdL3oFxXHakqVM/nubQFmJJTYCruYYjlEN4I47zQ+2QdOaZFimuSGDQ9Zx9usVhwmyjxqiPe0v39fy7qMyWPgFLX4EZbA/4k0bwAoAMB+APjAqb+/q9svzk8nELhN4nTRVESftUma7+np8X2/8qIn9jSmY5Avm8je8zxMJpPK/SltRkX+tF02m/VbgNK16gQCXRodFZpJp9N1hUl0AUtjY2N+ARaXtC2RHHSBeAMDA9r7pvJFqywSNPZUKqVM26P7JLa9RDQTSZg8el28gimSWhyrqfGJXOlNhO45TaVS/vyaYilM1g6bH5rGJ8+JrsubabymyH5xjm1apUqAc3GRLSfE7etnLCEsgT8g/Z0CgG8CwH8BgAO6/eL8tJvAXSRO06IsRknTwmDSRE355URWZK5Tadu0ry6yWtQCZc1J1ZJzfHzcqMHprntiYqJOC9ZFKcspXiayUc3/9PS0smHL9PS0sYylOA5TbjtZNkx9sOVe02E0cDknWSQLsfIefUcBgC6CVblc1sYu0HMl9mmnZ6ZcLiuJWbxeUZAUx0blZW0Ci+5ek3CiI0NVoJ4qIM7V1x9Gq1yJZOYa18NoDmEJfAEAzpa+WwUAVQA4odsvzk+7CdzlJdWRpSoFyVRshHx+JoKnIC/q1y2TKO1retHIhC/uW6vpU3p0Wq6p8hZp4LLfU54rl5rmY2NjfmSxHC9AgWzkh6ea4kR6IiGJfmZxHCYBRQwwNJmTRbO1KaBJZ4qVCVSufS8TCo1P9XzJ1zM1NYW5XE7bzIXOJ7eKJSuEqhyu/LyJEN0ROmGU5l437/RcuJIhzaspS0KHsEQclPij9B27NsmJ+vwrUWhpB8ISeB4ARjS/XaLbL85PHAQeVfQpHUulpaxfv95Y81uX/oJo7lY2MTHh968m8664Le1rMyfKJTdtJKVK9dERiMo3PjIygoODg77wYTJDmvzRspXARAI6cqP7Rr/r5mpsbMz/TSfcTE2drtMt58DrApp0AY8m7VFeJMXgQdlELAorJKCYrAhTU1PWnGodbO4IVbnh8fFxTCaT2ngHEl5Eocf2vjZDLM1ola5rSdS+46AEHtX52QfeGnAamQZBH0DbwqD7nTRlHbmIUehTU1N15kKbbzCRSGgLbNCCaSq1ShAFCZNJc2BgoM6XrdJ2XaK8M5kMptNpX/sqFouYyWSUgUAkrIi56wSxGte6desCWQcoOp3mmYQInWmfCN9U956OK59P1+hGPL9NiKDnTBRWbDX4dQVPTCZmFxJTkZX8rKoEAXkeyuWyL1So4grkAjwu72szJBylVukadxH2HEH7zBNacY2M6MAErkHQB1nlFxYrb4Xx8Zk0IUKtVmvQQkXCkdPTxEheIluVdiaCgsCy2WxDoBYVB6FIW5NmLTekMM2JShvr7+/XEqMqz1VcQFS5vyq/vTh3RP7inOii/onwSfAiy4Pcq1p1PhvxiM+HjYBE64ktQ0F+7srlsm8NKBQKmEwmG54JmwZuuh4xfz+VSllLlIoav853TnBJDVNds247FVqhnUblOw5L4OL5xTmXqxIyOgNM4BoEfZFkc6TsSzUtHKoXOpfL4fz8fIO5lRZA0nYREQcHB/3ULh1RkW9YDJQzETb5M8kCIPa4Fn2IAIvY23s6ylenZZK2KwoLJu1X9X0qlWoQVuR2prRQqeZUrr5Fle7oXOI+YqWwsbExPyDLhUApRkGlgcjPgQuhiOc0bS8SgRyAR7+JFhx5sRazFKiFqvws6XzgNg1S5w4Snz1ZAzdp37KrwTXSu1kSjts/7CpguI4jqAmdzs8m8O5AWB/4a1S+bgC4BACKuv3i/LRbA3fxgZteCPmFpOAck/mWoqhV2qr4opGpWdxPF/gk+iZ1hVzK5XJDP25aKEgDlRcX1WKqqoE+PDysDaJSdaWS25nSOGwameg/F3tN6xYvIn9XAtVBNk/bMg3EZ0H3HKlaY5riI1RCpY5gh4aG/HuZTqdxenra90uTpcEWrHbs2DGtH5ueS9ncT8Kq6P/Xad9BffPtNu3aslFsxBmEXMP6wMPGOjBai7AE/nUAeJ3i+9cBwP/W7Rfnp9N94HRM14VDPn/QyG/xvDIhiH2+RX+1rCGarklFnJOTh7Gv7y7s67urYd5UFcRoXGS2zefzPlmpzOREFqr7Qj5w0XpgWiRlsiISPHasscQsXTeZEV0I1HRPRUuN7v6JApecQudSyYuyCMTnrVqt1hU9Ea9FR7D0/cTEBM7NzRndRKZnxhbBL1pddPe4Uqk0WJPIKqLT1OVo+E6Aba2wrRNR+qlVCGLRYLQXYQn8XsNv/6T7LcgHAN50qtrbwwDwh7bt2x2FbvOBN3v+MDnWBDJ9VqtVf/En4iRNXPzepQ0jXd+qVXtwZuaIr60nEvfgzMyRun0WFhaUQWgiEZF/XUdm+Xy+rmmIfF9IgHAJ9rIVnDFpxfJ9CaLBqcZEbT9tFhSxPr3LOU0atQjRwqO7ZjqfqSCPeLwgKZFkEXBxE1Auve7YovAmxx50Eok3a56Oyk9uQtxCAiMahCXwHxh+e1j3m+sHAHoB4IcAcAYArAaA+wHgLNM+nZAHbvKBNwvT4mnT4Eh7UeWbj46O4tzcnHJBIfO2fGzyRScSCdyw4Z+xv38f9vTcqe10RYvL+vXrfR+rqvmIiUTkACwVdP5sOXLZVlhGR/C2muAiVCRvEgzEYCFdcFcQwcFWQyDM9rb7Q2NT9QDXFf8hocwlUI9K0spjFJ/rVminUZjfmzlOK8iVfeDdgbAEvgsA3qv4/j0A8CXdfq4fALgIAL4l/P0hAPiQaZ92E3jcUrFqAdRFfJPpUPZB6zRcU79vVS32XC7n+yOpbCvAojKYjI41NDRk9dW79G02zad8D+RofFv+PM3V4OBgU9YU3eI3ODhojAo3jU1X7Ee3oAZ9HlVuBfn+yGZuIqC1a9ca23VSgZ5KpVJX7GVoaMg/vvh8m1wYJreIyZIgxqKEJU6dUNhqM70q4FCu8hfVedoZK8CwIyyB5wDgbgC4HQD+4tTnDgDYqyvwEuQDAG8HgL8W/v4tAPhvpn3aTeCtkIrFvGZdelgmk1Gm/9g0XN2iZ2rDKJvdK5UKTk4exkRibwP5rV271jo/qmYoojCiCmASIWvgtPjIZUxt2kWz1hSTCVingRKCmqB1MRZ0P0zby7At2ESycu0Al7K2KreALLjQHKuK1YyOjjZU40NEv5IfPYNDQ0NG4awZrdIUGNhK7dRF2GKsDDSVRgYA2wBgx6nPr9q2d/24EjgAXH+qkcr+8fHxOOfJijhNTiJxDwwMKE3eGzduxMHBQWXqEAX/6EhAZ4anBYsWWlGDV13vyMgIjo8/gps2PeULFIVCASuVirOvniK9dWZ200IlBomposhlotSRVbPWFNf9VSbtWq3mV7+j+TOZ301ZDnK2AZVibQblcrnBYuNyvTJhy7+brCf0r3yNqkI1IyMjDalv9B42K2SbrjNqYd2EbnETMOJHWA08AQD/FgD+GwC8DwBW6bYN8+lGEzpiPA++LjiO+miLmrFOE0qn05hIJJSpaBMTE1gqlZSVt4j46TpEX63JJy9bCBD15nFTepupkI1urk3BVs1q0K7701zK+8tkLZOYSQjUjWnt2rU4OjpqdI+IVoQohEqZyFzmy0bopmOI24r3Xef6yWQyymejWcHMNMZWRmjH6a5j33d3ISyBfwkAPn+KvG8FgE/otg3zOdUY5REAmBCC2KZM+3QCgQeFC+G7RP5SNyzTi03/XnHFFXWlWcXqaeLCSCQsRn671Bbv6VG3wlSZx0dGRnBoaMgfS7lcxsHBQf/8poAu0yLT7AKn0vRsaVvivtlstsHESR3WRAQhMdXCOjw87JuVTdcszk0Umpo8TheTriysueY2y0KHa2aGy7iDzoeJ3GyCZZSIUwPn6PPuQlgC/yesJ9vv6LYN+wGAfwUAD52KRq/Ytu82AneVdF0WKdrGRvb0coomeXmR0WlK8oute9HT6XSd1icSx9DQUJ0rQDbn6iKVZSIwadhEoKrzi1qcqXMWjYXGqmuxqQLNi7iQk++eoqh1x3Exk4tzK7pEdPejUCjUlc81td50hU6YoMhzsaucKqiN7otMdiohUnxO5POa0gFdx226lyoyFp8dOVVNFVAah/Yap5bcihQ1RnQIS+DfMf3djk+3EbirpGsiZVpgyJQYpLOWaQGUNQnyx8o+SpXPVbWwqbR8lXZClgR5PLLmZhJqVJXjRFeATlsUW0qK1xZUIzEtgLZcbpdzidcunkt1P8QCMGJp2Ewm0/Rib3JhiG4WXYEbHQmZSNBF87dlC7hqyDaSVB2nldprXJo+a+DdhbAEfgIAfn7q8zwAvCL8/+e6/eL8dBuBmxZ6mTxlkzf5wGmBmZ+fx5GRESwWi8roaZE4xsbG/Cj1ZDLZUNd6fHxcuYhSsxIRYu1qXV9qEjbEY4pkQkFatZq++hNVkaNKaLpFRifsZLNZpxas2Wy24fhBNRJTBLptkdWRsKi5inEBKkITtW2xHG8naYamOAWTdUXnmiEBU2XVCYswRLYctFf2gXcXmopC76RPtxG4yeQpEp2sYeRyOT+ATdy/XC5jMplU+pnlqNxcLoeDg4O+KZBImEyfOs1cjggnjVvWnGUiEUtl6haIfD5vtAjQ3NDxVcew+eURzYsskaS4TdCCKKqxBYn+FoU3lSm6v7/fdzOong/qMb+wcNovHoVW5aLxuZyH5sdUrEV3f1qpHYYhY1sMQ7dEdnfTWFc6mMDbBBOR6TQsRLM2Qgug+PLp8mJlMiYp26QJiwRHGjfV1zaZcnO5HCYSCb82t2o8FLCm2rdUKvn55qLG7mrCpH1lv7G8jajp0ja6kqSmfPSoFkASasTjLCyc7pdO3eLkqmeklVJketRBfQsL9T5vOq/LeWhudddmi29olXYYRlgI4xZgMJoBE3iLoAuIkb8TF0HTgmhbYMQgLFVTC1VOMu1rMwOLv09N1dcWN5mox8fHjYIHaehi8FcikVCmuKkWP13KnWjaHx4eVla0q1QqODY21kAUPT3qpiBxmUXF66f68eI46dx0v0y5/RR70GxnKRffsyx8qs5Tq9V8c7eurKqN7FqlHYYVFtrtG2esLDCBtwBBFgOZHHWLs8nvPD097fvNk8mkkwYpau9yy0uR5GTtnwhOJDyd0CFq/vI1pdNpZZ9pGynIcyx3+lJVI9O1O6ViIbXa6WIqiUTCWv7UBLkIjy3AyvSckCA0NXU671gXlDc/P4/j4+NYKpWUrhXXDmqI7nnfovtHZdmxBQaa+qi3A7I7Q46id8Vy8I0zOhNM4C1AEN9YuVz2/dCypiL2SKYANXkhLpfLdYs1kaJ87rGxMeV4aNEVu5IR8ai0f/o/XYeuoAiRjioti5qMUFESimCuVCrOi59qjnX76sZI5nkxBmHDhg0N5ChGrJsQtEOdTVMThQxZs6VYg7GxMZ9oxJruchS6rh+8y7hcAzBFomsmMDAI4iD/Zk33JrcR+5gZzYAJvAWgBUteXFRpX8PDw3WaqFhvXFcmVdQG5YYTpshu3YJUqVSM55JJTtQAVeUtTcUuZCsCERydQzb/igFyRLjiHIvQLZymxiAuFhAytdvgUoRHRE9PD27desJvAkP3ioiNhAwVgajutcmdIX8nCwOyq8c1/1qXKijen7hMyiYfdDOk3ux4ddkF7Wx32ilWDkZzYAJvAUhbVgVoySZeWwS4/D29hARaxHUESPtRapnKjKpbsMQiIuKimM/nMZFI+P7NoaGhumputFCRP9p2HiI4MmWTMKGKujaVGlX12hZNujaicYlqNyFopbBCoYAzM0dwdlbdmERn9tbda1dNV2xYIwtUYhobWWRUgX1UklcnvIn3J65gNFPsRjPnisJiIFpJ5DLDUQgvQdDs/NvIf25uzn//0+k0zs3NxXEZDGQCbwlqtZqRgEWETa8hkNYnmrZNL2sQ0zP5u2UNWDbb08KfSqXqWh6uW7eubuE3WSbEuSPBQOfTVlkFaIxDQ0MN0dImuGjgYl65CUE08MnJw9jXt8dvx5pI7MWZmSMNqWimIClXTVnUwHUBabLfXSUAUSyGS7CWPLYg5Wld4Uq0QQkzSotBJ/jDm7ke23oyNzen7d3AiB5M4C2C64trakiiIxNx8SO/q0iOYnerVCqFyWRSW55yYWFBWxFNFaSUy+XqWoVSH3A6ztjYGHqeh+vWrasrjykSsuqYohndpCmIc6jS2FXmdoJKU5AFAQqiU0Ws24KagvjA+/v34czMEZ/ASRMX5z+TySjJVk7jI4JPJBLKADcxt9wWoS5q52RJot/kZ9r2jMdttnUlpjDac1QWg06ISG9GiLCNX7dOpdPpJkfNUIEJvEVwNe/p0pxUHcOoqIsMavmoIkeqqCYSibywDg4OBkoTSqVS/oJABC4HXOVyOcxkMn6g1fDwMM7NzWmFhUwmY80JFqPNqZ65yfJAvcVrtVqDpkABgkT2RM75fL4ucNCmmaruhdwK1mS6n51FBFg0xi3I8+E6T6JPm74zWXZ02jlZSORnut3kpLrnqgqCYcYUlfARl/sgCJq5TzbyD+o2YjQHJvAWIUiAjSnNicyORAq6iGiT2Z5M2/39/dqxUiS86Bc1mfdJYxQ1yETiHpyYmMD5+fkGE3s+n/cbfOiOaVosdHW/ycwvm3fp2ovFIk5MTOC6dev8ubEtqi4ai7gAylYPsfiMOK9itzdaVGdnl7Rxm6Bkmw8bKbhkDdiahajM4jofeKugyupoN2HaxhhkLFEIEs0IEayBdxaYwFsI15fPpK3rtGr5WKYIdMrJJlO1anyiFppMJo2lTguFgu+zFX24k5OH66wM8n6pVEqrPVK+cxB3QrFYVOa90+IkXrs4N7ZFyUVjIaEjn8/j+vXrlaZrlWWDgsRMkf02C4hO09bBdi4KljM9P+KxZMLspOjmWs3eea5bEKX2HlYQYB94Z4EJvAOheknIl+xq/jJpULQtkSHlDItBRZRKls/n/TrrqoIg9PKWSiVMp9MIsIirVu32BQMiNp1FQeUnzuVyWK1WtYuFiVhUGqXYdGVgYACr1WpdgRYbUdnM8eK8FovFwHEMqVTKP48Y2S+b7k0BZ0EKxsjPUK1WX7uerklX7rSV/lpxjDbCIfeNuE+nad/NoN0uCgJHoXcOmMA7DHL6kNhZihZTlwAUMiWrIrPJpCt2ctLlfZOZlwqaVKtVX5igFDHRdLp16wmcmTniL5SqnHLS8CgATyYfMShO9nWbop3p+sT5US3iRI70nUupUVGT07VLrdVqfopZkEwCihVQPQsuNciDFoxxeYZUwgK5KVpNgK5ELBO47jmhVrxRjq8VVodOiGBndBaYwDsIpoWKCNmWjkaLCRFNuVzGoaEhZZoXda0ySfbkq7VptTrNUqd10jl1BUl0mjdtIxePoWI35GYgmMhePKeq65tsbjVpriQUmSwfuntHfnkdidvIIWjBGBdNTreNrgtb0DEHgW28RNzkvqG/bTEUURBtK7X8TtHAGZ0DJvAOgukFpd9UdcrFHGFVcJcu0ps0YNNCRwuxSfK3FTwx7SuTwtTUlE/CIgmQwEAQNWJVC1UqRhK0mIlKw1YFs5mCEtetW9fgjqA+6yQoiBaR0dFRv5ysmGqnyxKQyUGXRkb902W4kE5YbS8OQrONRUfgpvcpKuJrJakuN5eADq2yaCwHMIHHhDAPoWmhkgOPRM2PTLi6zlQqszJp6dls1thylLRMnU+XiNYmeKh+o+sTTcg9PT04Pz/vbBLWHZ9SwkwBb/J3pnQs+Vy6846NjRnHXqvVMJFINAgdGzZsUPZbn5ubU+bpk7AxOjqKyWQSFxbsRXtE2J7PsMQUB6G5HjOIDzwq03OrzdrLidxU17JShJSowAQeA8I+hLaFSjaP0wNPL4HOxyoGdqnGNjIyUlfcg76bn5/3/a4qk3VPT49PlKaSpaa5IDKlCGbSQNesWeMfO5vN4uDgoHLOTP7m8fFxZdS+XMxENNGbFmPR12w6r41sgggV8rYqc//o6Chms1lj2lfQBVDnA7cdJw5CC+sDp311KYXpdNqpKY0JbNYOB909de0+yFgCE3gMCPtSuy5UYpU1l9KZQ0NDPvGYNEciZVXrxFqt5pOrqqAMpQ+paj2LPmpTj2uV5loqlYzCjynlThRaxMBAuh4x8poC6XT3rVZbyuHO5XKYSqW0+dOmXG2CySIikowqgl+3wFFgYFQ+X7peVc66CS7Pvni9KnLVjSes5ql7r+SCRmHAGmM46J4Tl/eHcRpM4BKiMFE1o4W4pAOJPjyVdib6j6nQi6jdBomEFuGSxqaKiKYWnJ7nYTKZVKYmmQpAyOMS75GqsQb5k3X3QNYoaRFWaeu0GMvn0RUtcdEg5I5xunOqIvgpxU51XeRvl2MHwvh84xJCXeY6DpAAqtLEdcF+QY69XMzarUIzFizGaTCBC4hKmo5bA6ftVC+BquoZBVdlMhltJLSLJkTb6F48IrlKpVJXPGNoaMgnSl0qlmsJRtUcyalVJCToBAK5qIeYopfP5/0xigt+IpFoOJ4YiZ/JZJzrt4tCjilKXhd8qGsHakonC6rFNCOEmghNJ3yK1xEXVnKZz04TMkxZDmzRcAcTuICoFpUgRCwSnW7BVp2fNGp5e5MfdGFBHcUuRm2rCJHGTUKAboy6dDPSvvv7+3FsbMw3yWYyGZ9EXVKhdNcsz1G5XMZsNtugmW/YsKHB901mcVGz7u/vD6T5ymOQTfaqFqAuFhGblkJjGxsb889J91gstTs4ONiUBq5yQYQFXZPoBhKJJU4yDZput1zQiWZ+05g6TdjoZDCBC4gyAMf2EKqChGwtQ8VylTozpIkQRLMzEXQqlarLm1aNSy6VqKvGJs+fHDmvKyOKaO/cJXdZk+dZJkmqHidGa6vM26LQQdfu0oaTvhOj6eVCKCZLgdiRTXWubDarFSjXrVtXd10uEfwqV4QJcZm6RQ3cpSxw2MVcJURRsJ/uGbMdp11k0uwYOjXQTheF3u757iYwgQtoxvQd9KFTnctWAIQWHVOA1tjYmPIYYuUxWoQrlUpD0IiL5qUjTfmaxL9NQSsEUXOU/ZVyn3MaRxByUZV0FQUCOrar5itH08v57OL1qgQj8tXritYEvb6pqSmtiySbzTZsL95fXeCiLbXOFeK5stkslkolp6JEYYQHU9Da2NgYJpNJp5KzrdJcTetHFGPolgpunWgp6HQwgQsI8wCFfehUL1W1WlWWHZXbIZpeSNdj0KJOOcTysXXXJTaroDxwcS7Wr1+vrDFuIkWX+aRjib/bBC452E0VdEZzJY7R5J8jwYWKzaisCbVara6HtmjeVt2DUqlUF7hYKpV8YSCIcFir6RvYuMzz+Ph4QwGbKBZ/1blsUfOI8eSiy/u7+OuDnj8IbOtHFGPoVA1cRreMs5PQcQQOAO8AgAcA4CQAbHHdr11R6FEvMrlcri6gTLXI2RaoZDLpm2rJx65bKOVKZmQFUJ2D/NliapFIZHJktmhR0I15dHS0br51xWhEU7NoAdBdF/nB6bgiUcvHJc2YxqhaVKmfOZmuqfkLke78/LzyvGQmNhGhyuS9du3aOmFJdHuYnktXDdz23NL/xTmhsRSLRV9YcYHuXDbtPqzwYNpP3N9Gnq3QXG33IS4BqhM122avNUhDn+WCTiTwSQA4EwBubweBB0XYh05lUqUCI+LCPTAw0KA9VyoVZeEU+l6s+jUxMWH06YpBVmJaluq6VClb4+PjmEwmfY1cJFkx4nx+fr5hX1UBGRMpy0SnC6jL5/PKXHVVEBp1RCOBgM4hVrtLp9O4Zs2aujKounahdF5xfzLbBiGxTCZTNxZVXIKqdaculkD2gdueW5qbubm5hkI+dL2uBGCyvsShfbpq4Lbjt0IjtN2HqMbQDb5lk6BnG3fQhj7LBR1H4P7Ju4TAm3nB5Ch0at2pqpQmFz+RSV4V6WzSKEdGRvxSrHJwV61WU2pypuIlorlVp8EODg7WpWipzmHqDCZL2Koyo6aSsqogNKoCZ7on1EaVLA8qoUoUKEzXL4/VZPK2WS/k2AgiP9k6UC6XG55J3RyJGnixWMSRkRFtqV1XEjG9I3H4f00+8CAadis0Vxc3UDdoz1FAt07Ja5/q2ldqhgETeJOI+gXTvdBiRDV1vrKNS/TDioRPkeey5i9eg6x1zcwcQYBFLdmMj4/7pGDTgIh4VOSl8uGbtD0VAbgGoY2OjvqmbxN07VbFMVWrVf96dNcvmuApD14nsIjBha5WHppj0aIiCndiNzeVVp3P5xt84DariItm18w7EmUUehgfd9yaq8vcdIP2HBXk+6YSlFWCo2t1w+WGthA4AHwbAA4qPm8VtrESOABcDwD7AWD/+Ph4nPNkRJQvmGtwm2kBNC0KRKDivgsLpwO0dCkdq1btxr6+PcoFj4ibmnSYCGfjxo2+ECKXXa3Van6vcfIju5bwFGHyt6u6hNn8uSr/uxyZXywWfTI2CRCe5+HQ0JAfCb127VqlwCJaRVytPHQOk3tFDKiT/dpr165teIaPHTumtbxkMhljyqGIKIg46oW4U7TblUTQQRDEPela3XC5gTXwDgG9xHLjEZIi5friJhOmbsGnvtNUXpNg8tnLrRrXrLkbZ2aONJji8/m8r/GbcptzuVyD6Xd8fFzpIxeFjiA+P118ga7MqarHtbioplIprFarxmhqz/OwWq1aYw7ka5uamsJSqeQXdRGb1Jhy6HWZBabAMPrXZqGQ9127dq01gl8+l+3+uBBWKxZiJs/ORRD3pEt1wyhjFzoFTOAdANVibSugYSJd0wJdqzW2UjQ93DKBT04exlWrdvv5vJVKpYFgdHXCycxMxCMunul0GkulUt1iSoKG6VpVCzCZiOVGHLa0JdX9EAUAk9+YSLtWWyrNanMDyGTa09PYO10U4EhAIuuFKlbCFu1O/5osFKpAIMpWcHVVmFwSQUh5JS3EjEYEFeDEGJm4swc6BR1H4ABwJQA8AQC/BICfAMC3XPbrFgJXEY68UOmCyMTFK4wGLgco2SKaRUxOHsZEYq8vZIjjU51PbDlKxxN9u64BK6QVqq6VjiHmUafTaW3QlWtREt382XzBshCTyWTqNHjVfqJmbArgE8cvlpwUO6qpniXx2kkg0lkSqOmNnIqjG5tpvDoEIeVWpHExWo8gVo8wFpKVFNDWcQQe9tPJBC5qUir/pIoYTIuXTRJVlTsV+3uTOVkMcLNJurOzSyROL5NrkRa5aQmNS9SwZY2bQGZ3k4ZWKpUatEZTZLeub7l8n+TFwuQLpjFXq9WGwEGdSb1Sqfhm83Q6jVu2bFEGlpHLQ0yJEUldFfCki8CWS9Oq8tV1/mvV2NavX+/sAycEIWXWwDsHUbkaWuEWMVU3XG5gAo8Z4gNr0o5ctZtUKmX1G5J/lF44qval2zfMQinuY9p/YWEphYqCtiiX3PaSiWSqi7qnQDLXuRMjv+Xj2haWhYWlTAATYS0sNLZFrdVqmMvlGhqmqEzV1G6VTOVE8HJRChJGTFHfqtxZ8Z6qrD6yNi8fUzbjy4GOLgt7kGdtJQUjdTKivA+6+6+KQwkLF+VguYAJPGaID6xJ+5BfEJ021swCGdRn7urL1BUaUREH7asLdKPIbpcFgwjeNRVNrvXtOm9EsHNzc3UkJpdTJRLOZDINaXpyCVpXE19YLdR2T8XfW0mUQc/FQWbtR5SWEFt8ThRYSYIfE3jMEB9Y04ug8j2GWbxMC3dYn7kO4vjEPtoq87MsDNg6r7mMxyQIJJPJOguErSKTaWHRSfCilUBH5qr7FqQvddjFyDaHrhYU1XiaJVQm5e5ClLEIumdNLqikQ5AMBtt2y+E5ZAKPGeIDq1uMXXzQIkwPnu4FkXO/5ePFbSKTX06dPzloFOnc3Jy1hKKLMGIbt2nBMlWoU5nAgwbZhFlobPe0VjvdeKaZ6Pwgz8lyWDBXIqLUwMmlJD9D1WrVKhBEuU7JFkSVW60bwAQeM+SHThWdHUTjHBoaqvNDysFHugjjubk5f/FUVaYKu7jK+7kKI7q66kHmgzA3N1cXEHbFFVfUjculwYGLD1x3fpNGrRIqWlW32XRPxTHoBIp0Ol33XTML+Uoya3Yy4hAGgyKfz/spnjSGKITsIKBjdftzyQTeAtheGhcTlS4SmHLGZR+zC6maIo9VkIlyenpaa1FwMV+JudpjY2O+GVqs0iaX9rQdp1gs4rp165yiuU33ia7TFqGNiH5kuwg5MEfWsFvVOUn37Imk7Rq124wplSPK249myCpK60nYcURpyqdjmYLqusFaxATeAXBZ3KamzHnCpofYFqDlsoiqTNW6bmCm44kLATVSoZdkbm5O2UUsn89rXyCVJk/55LrrNeWD6iwYJtJXCVbyuHU+btscNbN4mBZK0Wqgi9qV56kZEuac7vajk4SoMM94HBq4rSphUMWk1WAC7wC4SKSqSl2I9gA12le3ny0liaAKFrMtyq7dw+i8YV5QW2627noJ8kKiK7dqCwAUj0P9ssXrswkO4nhaEY9gqx2tslQ0M7ZOIo+Vim4XolTWtqB9EsRj2coei9tSjwYXq2ArwQTeIbBJpAMDA9qHTQxQUx3HRQO3PZAqP6/puKKPlYJEbGTrusCI16gq8anaR9bAy+Wy3yZU1px1VdNUsI2ZFgNXH3cURCdGx8v54DQ22Q9PleNkk77KHRM2VqKbfY3LAd0mRKmevWb60quOryp7nMvl8Iorrqir7lgqlRqC3Toht5wJvE0IakLyPE9rqrVV13L1gYtNNWS/rEoDr1Qq2i5ppOGJC7ctB1RXa1z0JcvRo6qa6xQoKH4/PDzsS9HUL9tF+qbvbBq4bnu6Plcfd7NaEs1PpVLBjRs3Nix24qJj88NHTbochd5edJMQpRqrrbx0M+eiuJtUKoV9fX3KIFNaA01xIq0GE3gbEOZFIkIWC4mMjY35rTBrtZq2jSRJr6JEKZvNbZHRunSt6elp5aKs6o2tIzsyhZEGKJqpxHafomBgOl4mk6nTFHUtO03R4673xiV6PUiVqWa1JNpfJwyl02nnBbvbNDaGHd0iRKmevaDCreu1yu+wTlBIp9MNkfPtrq/OBN4GhFkYbXmLpmOqaoDL7ShdcpPlKPS5uTnteOl4LhW/VKYxCgKj/NByuYyjo6N1xzNp9FRYRldula5N9f3o6GigRU40WcsFXVz6jcvHchHudNqz6Oc3WTtc0O0+U0b3oqenB+fn5+ue8cHBQed107TW2FyMLmmhrrnrcYMJvA0IuzDqfDZkytE9dLpocdHMHKQ6mDgeHdGRRi+bqWu1Wl3DDxcffTabxWQyWfcdormusigQBClhayNc0zWTQEWmOFEACXI8m+ZgspbQnOjiDVwrXiGyBs5oHwYHB5XPOK0DNuuY6tmtVCq+IiMqQXK3QN16KSoz9C7ZelPEDSbwNqCZhVG3r6kYhy163VafW0cytohQXaCYbKKyEWylUlG2IdXVYJcjyU2me/FFHh0dNRKuSTu2uTCCHs8Ek0WBjik3UAmjNXSTz5SxvKAzY2cyGSfrmGpNETNGVIJ7rVbz1yxboSVSblTFtFoJJvA2oJmFMYg2OTo66vu6bQKDTqvTpX4NDg4q869VKWmqaFLxmLpgMtHnRH5p+Xhr1671g9PovPIcqeZ7bGwM165d22CCXlhYwHw+7x9fzFU35b3r5ljMEBBdEOvWrdMKTTZBzmYtIUtNf39/qIpXIrrFZ8pYXghjERSheh9pjaA4G/FZJoGehGPRRZXNZjGTydQdS7QGkrAcxFUWFZjA24SwC6OJjFXHHBgY8CVElY9Z3FblV9Wdz0Q+LgKJOFZTMRbx7+Hh4QYBpVQq4cDAQJ3JWGc+k1OqVMSeTqcbBBkKHJRN/4inhSeblcPzPOe+5TYN2bWWOsUN2ATFuEmahQBGUATtFyBDfrdLpZI2YwbxtHAQJrCVyD+Xy7X82WYC7zIE1d6pTKbcH7y/v9/pGKZAMVv+c1hNL51OKyupjY2N1V1DuVz2z+liWlddnyxIqEx3pnQ5WlRMGrjOxWGqrGdCkFrqrU4Vk8FmeEYYRNEvQEyrtVm76B01me5V2TuIS+2LE4mEnx20bt06Y4BvlGAC70IE0Wgo/UzcnshIhPgwi8fPZDKYy+UazLC2nMxmopVNQoOsQZP/mkzzIhlTFLqr1kf76nxn8rWS1E2R3SoXBgkirn3LXS0XYjqgrpa6C3nGHajGgXCMsGi2X4D47JkUDtFdqLLAjYyM1LnqRPN7rbbU1U+VRdMKEmcCX+ZQLeKmh1kX4CHmZQ8PDytTv1y7d9mgM4Fns1k//31oaAg9z8NcLucTtUvfbxOI7OVzmwQKOj9io2AlzrPOJCj62ykITQdbEJ0tPYbOKd6XuFPFOBWN0S6Iz57u/UulUlgsFnH9+vX+ujY4OOgLx2vXrtXWkaAAWFMMT9xgAl8BkBd3XZEPUzCWaGpSEZac/9xsxS65BassFY+Pj+P8/LwvRDTb07dWq/mme9cKUNlsFtevX68NXhHnUmUSFAUjl/nS3Zt8Pq8kdhfyZA08WrC/v3Nge/9E4ZfWDjHrplQqKVNhEU+TP1kFmwm4awZM4CsQJk3OtujrtKeoFy7xeLZCLM36WWl/Im/R5ZBOp3HNmjUNL38ul8PBwUGsVqva4iiqQBoxCl3uC2+D7t7ocr518ybXzmcfeDRYSdfaadCluureP1MgKxV8Ib+5iaBNJZmDVD0MCybwFQod4bpo4K3WnmyBdPKYZd+47iUS/cnk15IFB2ryoYpiRzztC3cJkmtWsNHdG1PkrMrHbusfz1Ho4bDSrA2dgmZcS6Z7pltfEJdceiQM9Pf3+7UnRL95qVSK/d4zgTPqoPOBz8/PhzJRB1m8Z2eXPjJ0L1mQcq2q1CnTdmJuPR3ftE+cC7XJVTE+Pm7MT3fp1rZSCDZusL+/dVAJ2iLk91HONhkbG9Nq19Vq1U8bVVn4VC69TCbjm9RTqRQODQ3VlYFOJpP+76Ojo5G9Y0zgywRRLsLisQqFAg4ODgaOlqbjuJoUa7Ua9vfvQ4DFhvHr/MfkAxdNWK5akCo6X9RMSUCQJXZ54ZAJP2roottJkBoeHlb67WmebfMRldmXhQDWwFsFl2dWfB9V2w8PD+Po6GiD+6lWq/natJiOKsbYkEVOXjsohkZco7LZLGaz2YaA37GxsUjeESbwZYA4fW+1Wk1rOrYtTK4L2uTkYUwk9iLA0lM3M3MEE4m9dWZ98YUpFAp++lY+n8ehoSFfwHDVgig/Xp4zKtggzp/OKiHOb1wLtWkOVYKF7DawPRtRkA77fpfA89AauDyz4t+m4E+5twRp5gTRHZdOp3F6etq4dsiZOOvWrQtd78EFTODLAHFJ/qYFyUXjdCXT/v59ODNzxCfw2dklEqfxuxyHCEwX0CXPhal2vEqDlK0SclW4oEFzrtqqyf+vMo/r/HUkhImlYWnfZs2+rHmeBlsi4ofpmVW9jzozORG3qF2L8SS1Wn2f8EQigcPDw9qsFFpTBgcHG1o3x+Va6TgCB4CPAcD3AeB7AHALAGRd9lvJBB6X7820MEepgdP4RR+4OP4gBOGqBYWdM1HTVVkmoq58prv2sbExZVpMqVTSlk9VndtWkMcF7PtltBKmmBiV4KTa3pQaRn5v2exNJnETIW/cuLHB3UgBbfK5lqUGDgBvBIBVp/7/5wDw5y77rWQCj0sDMi3MLjW15aYlOrKi8YsE3oyf1kULCjNntnG4lH8Mel7dOeWOa3QcKmbjmmEgtlgMa/ZlDZzRSoRZD1yLWSUSiYa4GsLCQn3DE/m3oaEhbUAppaStKB84AFwJAF9w2XYlE3jUvjebOVpVMcyUTymTSRiijzpIT9dX3XRcG1G5NGAIo63Wao091F2iy2WYzPHNzC37fhmtRtD1QN5eV8yqv78f169fb0zNTCQSyrVj7dq1xndsxUWhA8D/BoB3uWy7kgkcMTqCExfjIE1BbL5XkbxdiT4OyNcXJDXORr4uLRDDaqtywJqu93ihUNDOY5yaMvt+GVGhFc+Sbh2am5vDZDKpbH4ipo+Ja8e6devqYlJ0GngcaAuBA8C3AeCg4vNWYZvKKR+4ZzjO9QCwHwD2j4+PxzJBywlhTMtiFKbpZerp6cFqtWoM9BoeHsZMJhMqoj2qa22GxMJq4GJgXFhtVdzPtEjIpjpbND1ryoxOQiufUbLEkWYsCvGe5+HGjRud4kVSqZT/7ulaNy8rArd9AOBaANgLAP2u+6x0DdyGuIO7VD29xVQrVVCILqJdRb5BpHLTtTYTcBXWBz4/P1+3bVgNQwyg013DyMhInbAlCye2IDwGo51oVTwFFVfJ5XINrZbJGkgWLdH8rXvvFhYWsK+vD0dGRuqOl8lksLe3N7b3q+MIHADeBAAPAsBQkP2YwM1wfTHCvkA6nxJ125Lb8InHtQWsDQ8PO5vybdeg+02sD26CTbgYHBz0I1Xl7miuC5GN4G3ZAXQvJiYm/GpQ8vFNwhaD0S60IqOBBO1isajUmEdHR5VxOevWrTOujQsLC37/BEohW7VqVazvVScS+MMA8DgAHDj1+SuX/ZjAzXB9McL6qOXjuwSKqSLag6R86MjQdK0m/3EYKV83X7Yx6OZSJ8CIvc1NQX+iz31hYSlqVr4unbBFXeYYjHahFRq4WILZdD7xPSVN3GSBq1armMlksFgsYk9PDxaLRcxkMk21OLah4wg87IcJ3IygudRBo8TlIKuJiQkr8S4sNEa0q4gvqFRuu9YwEdw66M5l6v8dpDKazvVA3ZJU8QSpVMqfI1WnNJdgOwajHYgro0YsCy02KXEtEjUxMeH3IdBZFHO5nNKytXbt2nCT4QAm8BWCZl4ME0mpSJ62N70cuvNHoYHbrjVKKd+UNqIag6kXu+p4prHq4g6oPzmZA2VhRZcemEqlOJKc0XYEjXcJYs0aGRnxy6XWajWnQkb0DooxLqoMHdN7FReYwFcQwgZPuZYuJDO7qQ2fSBSq80fhA7dda5RSvqsJLp/P+2Y4k8QvH89mih8eHq4z2a1fvx6r1apP5qqSr0NDQw3zmc/n/cUs7JxwKhmjlVC9xyTA9vT0OFnB5ufnGwJPc7kc5vN5//kV38FyuYyZTMb3cVMKmalkapyWLSZwhhUuGqv4N23fTMqUKlBMjAhNJpPK1DZTaojtHGHgco0uKWC6ID5TyUeyfMgmQrp26pok75vP5xuIP5lMNmWV4BQ1Rquhe5eKxWKdgiFCFYeSSCRwaGjIN4uTAEzPr+o8qhoXuiC3devWxTMByATOcIDL4kySpud5dRpe0GIp8nlNeeUUfCamZ6m09bgjrINEjbsSvqi5q65HXmRcj60LpGs2+lcU2uh4xWLRN+czGFHD9sy6Kh5U/MhkSXMRTqenpxuCdnO5HE5PT0d52XVgAmc4QVyYBwYGlJodSb4LCwu4fv36usjpoASqehl0LTzp36mpqVhb97nCRo5iLrbL3Ijb61LxEN0WLJXm4LqvCVTIR1XEgrVwRhwIas0iH7jYs5taitqEAVeL3fT0dF0aWZzkjcgEzggBne9JRyxBMTc3p20KIB5TNJP19PT4n7jzSBH1L7RqbqLo+IVo94eb/OvHjh2rKwUpaxJBTOCqa+8U4YnRerQr9sFlHSqVSnWEmkql6txrVCehFelrcYAJnBEKolaYSqWwWq3W/d4MaVJ6lI2I26WBqxaOXC6HyWQSE4mE0l/WbMcvRL3GQUE5umsnjVsX1CNqLLaF2FQnIM6+x4zORLtjH8RnNpVK1bnZZIFVJvPBwUE/Lazd1xEWTOCMphAHaZqaAohm+rA+8GbTVExjy+VySmGm2Y5fNBZTapptEYrCOmHSVGwpcozlh07SXKempurKmJLASjUT5CC1kZERTCaTODc3h4jdmUXBBM5oCnNzc5jNZhtIc8OGDaFfAFNTADFFJEwUelBTcdAqa0TkIqJc0FSLjDgeWSMRryuKxdZmxu9GLYYRHq1yWSHaCVZ+/np6epRpYvRMkntLbPfbbWACZzQFCmgTSXNsbAyTyWToY87NzSmbAsgBIWEk5iAkpttWNkXXavUd2zzPUwoeZCWIWsp3vSYVwY6OjjoH07mcqxu1mJWGKO9RnBq4SxaKisTFNcMUfyJmznQrmMAZTSGu4gVzc3N1/ioycxHCantBIsJdqqypKjKNjIxgLpdrMNmFKUjjgnK57OxjFxe4bDaLpVKp7m9b3WbWsrsbUd+/uJ6HKAJl8/m8tYMYa+Ad8mECbw90gVFBXoq4NWndfrbFx5YbWigUtOUTVUVU4giwo2tQtUQ0gfyFKo3cNa0tLi27meOzBcCMODTmdlmVbKZ6ehd08SrkA4+z2UjcYAJnNAVdD2zXlyIqTRrRzfcmni9MHqk8NpOWLi9ocfgL5cAd8W8TOjV1phmNjq0DdrTSZ90MXMapq2lAmJqawlKppCyVunbtWlyzZk1XkzciEzgjApTLZT+obGBgINBLEYUmHWQ/xHqzuW2RsGkXrtHy5CePmjB1TVNsLgy6pk5bzJu5r50okHQaumWOdBkNY2Nj1poGBBLoSqWSvz6p3HHdDCZwRlthIpEgEadhtK0oFjNXX12xWIzFBx7WhVGr6TsxmZrNxI1mhIpOFEg6Dd1ipdCVEE4mk041DQjL3aXCBM5oK3Qk6tIZq9mXM6rFTE7d0uWBxxGF3gxpqYLfdHXWWwXWwONHN5AaleYVx0lV0+h3FtaYwBlthi61SVVrPY6FOOrFrNUk0uz5RHeCqc56q8A+8HjRDeSNaH+uWVhbAhM4o+2QF5VuLsnZahKJ6nydpNFwFHo8CPqsNBPbEvdYWVhbgonAvaXfuwNbtmzB/fv31313/PhxeOKJJ+Dll19u06gYYfDkk0/C4OAgJBIJ/7uXX34Zjhw5Ahs2bFDu84tf/AKOHj0Kx48fh76+PshkMpBMJmMfayKRgHw+D319ff53u3btgp07d8KhQ4dgcnISKpUKbN++PbYxNHu+HTt2QLVaheeffx6y2SxcffXVcOONN8Li4iLs2LEDDh482NLxMOLB5s2b4cYbb4Rt27b53+nu8Y4dO+Dmm2+GWq0Gl156KezZsweuuuoqePvb3w433nhjS8Zre474OQPwPO8+RNyi/FHH7J34UWngjzzyCD799NN48uTJZgUdRgvxzDPP4Pe+9z08evQonjhxAo8ePYrf+9738Jlnnolk+6hw8uRJfPrpp/GRRx6J9TxRQaWd6tIAS6VSXY15V62WNaPORRArSxT1HRjxA5azCf3BBx9k8u5SPPPMM3jw4EG899578eDBg0YyPnjwIB49erTuu6NHj+LBgwfjHiaePHkSH3zwwdjP0yx0xJpMJpULdTqd9sk7CCGzb7JzEeTexFVhkREtlj2BM5Y/7r33Xjxx4kTddydOnMB77723JefvhudMt3inUinjQh2UkDvJl84IV08ckTXwbgETeMwQm3p84xvfwNe+9rX42GOPtW08N9xwA27YsAFnZmb8z89+9jPjPs8//zxef/31eMYZZ+A555yDs7OzeM899xj3oev+l3/5F3zb297W8Lvue91xZPyP//E/8HOf+xwiIm7ZsgUXFxfrfj969CjeeOON+Kd/+qeIiHjLLbfgAw88YD1fGHTCc2aDqWKcaaEOSsisgXcOdDUKqKOfyR3SbIVFRmvABB4ziIC+/e1vY7FYxIcffrit47nhhhvwYx/7WKB93vnOd+If/uEf+lruI488gl//+teN+zTTjSzocS6++GLctWuX0Qd+zTXX4Fe+8pVA5z5+/LjTdp3wnNmgI9bR0VHtQm0q9qIrYck+8M5Bs8JUO6PQGW5gAhcQRwpKMpnEO+64AycmJvDQoUP+99dccw3u2LEDL7roIpyYmPDJ5eTJk/j7v//7ODU1hZs3b8YvfvGLiIj4b/7Nv8GvfvWriIhYKpXwX//rf42IiDfddBN++MMfxkcffRQ3bdqE73nPe/Css87CK664Al988cWG8QQl8IcffhgLhQK+8soryt//4i/+AqempnBqagr/8i//su66EREfffRR5YIhfv+Zz3wGr7zySpybm8PXvOY1+MEPfrDuOB/+8IdxenoaL7jgAjx8+HDDdczOzuL111+PZ555Jp5xxhm4a9cufOaZZ/Azn/kM/s7v/A7eddddODAwgIVCAWdmZvDhhx/G7373u3jBBRfg6173OiyVSnjkyBH/WB/4wAfw3HPPxY9//OP45S9/GaempnB6ehovu+wy5Rx0A4GbtDEqMSkv1LqGJ7lcDiuVirGEpWi2ddH4GNGD3RnLH0zgpxCX5rBq1SocGBjA+++/v+77a665Bt/+9rfjiRMn8IEHHsBisYiIiDfffDP+2q/9Gr7yyit4+PBh3LhxIz755JO4a9cu/P3f/31ERDzvvPPwggsuQETEa6+9Fr/5zW/io48+ir29vfjd734XERHf8Y534N/8zd80jEc2oV9++eXG8X/1q1/FUqmk/G3//v24efNmfOGFF/D555/Hs846C7/zne8gYnACn5iYwOeeew5feuklHB8fxx//+MeIiAgA+LWvfQ0RET/4wQ/iH//xH/vXIRL4e97zHkREvOOOO+qO+zu/8zv+fIsa+Ote9zq8/fbbERHxP/yH/4Af+MAH/GPNz8/7223evBmfeOIJREStq6EbCBwxuD+UCECVpy9Cp9WxNt5esDtj+cNE4D0tSmWrg+d5f+x53vc8zzvged5tnuepE38jxs6dO+Gmm26Cbdu2QV9fH2zbtg1uuukm2LlzZ1PH7evrg4svvhhuuummht9KpRL09PTAWWedBT/5yU8AAGDPnj2wfft26O3thVwuB7Ozs3DvvffCZZddBrt374YHH3wQzjrrLMjlcvDUU0/B3r174eKLLwYAgImJCTj77LMBAODcc8+Fxx57TDmmf/fv/h0cOHAADhw4AIuLi6Gvbc+ePXDllVdCMpmEVCoFv/EbvwG7d+8Odaw3vOENkMlkIJFIwFlnnQU/+tGPAABg9erV8Ja3vAUAzNdE+Z9bt26Fn//85/Dcc89pz3X06FF47rnnYHZ2FgAArrnmGrjzzjv939/5znf6/7/kkkvg2muvhf/1v/4XnDhxItS1dQq2b98OBw8ehBMnTkAymYQvfvGLxud9cnLSfx5pvxtvvBHOOuusuuNeeumlcOjQoYbzxfVOMdxQqVTguuuug8XFRTh+/DgsLi7CddddB5VKpd1DY7QAbSFwAPgYIk4j4tkA8HUA+KNWnPTQoUNw6aWX1n2nW5iCoKenB7785S/Dvn374D/9p/9U99uaNWv8/y8JU3qMjY3Bc889B9/85jdh69atcNlll8GXv/xlSKVSsG7duobj9fb2wiuvvNLU2AEApqam4P7774+dvHRj7+vrA8/zGr6XQdvo/g4CsQDMX/3VX8Gf/MmfwOOPPw7nnnsuPPvss6GP20lwed5VBHD11VdDqVSq22/Pnj0wOTkZ6hyM+LB9+3bYuXMn7NixAxKJBOzYsQN27ty54oqdrFS0hcAR8efCn0kAaEk5ONI2ROgWpqDo7++Hb3zjG/CFL3xBqYmLuOyyy+BLX/oSnDhxAp5++mm488474fzzzwcAgAsvvBA+8YlP+AT+8Y9/HC677LKmx2dCsViELVu2wA033OALGY899hh84xvfgMsuuwxuvfVWePHFF+EXv/gF3HLLLbGPR4cvfelLALB0zzKZDGQymbrf161bB88//zwAAGQyGRgYGPCtBX/zN3/ja+MyfvjDH8IFF1wA//E//kcYGhqCxx9/PMaraB1cnncVAbztbW+DWq3mpNXF+U4x3CBaTw4ePMjkvYKwql0n9jxvJwC8GwCOAsA2y+aRgLSNm266yS8deN1110Vm7hscHPS156GhIe12V155JezduxdmZmbA8zz4z//5P8PIyAgALJH7bbfdBq95zWvg1a9+NRw5ciQUYf7lX/4lfP7zn/f/vvXWW2H16tXwnve8B/7+7/++Yfu//uu/ht/7vd+D17zmNbB27VpYv349fOxjH4NzzjkHrr32Wl/AeM973gOvf/3rA48nCiQSCXj9618Px48fh09/+tMNv//mb/4mvPe974VPfvKTcPPNN8PnPvc5eP/73w8vvvginHHGGfCZz3xGedwPfvCD8IMf/AAQEd7whjfAzMxM3JfSErg+79u3b29Y9C+++GLYsWOHX8JSp9XF/U4xGAwDdM7xZj8A8G0AOKj4vFXa7kMA8FHDca4HgP0AsH98fLzBwd8JUeiM5Y9uCWKT0Yrn3fUc/O4xGMEBndzMxPO8cQD4e0TcbNtW1cyENAQGI07wc9Ycdu3aBZVKRamps8mXwdDD1MykXVHorxX+fCsAfL8d42AwGK0BR6szGNGjXT7wP/M870wAOAkAPwKA97dpHAwGowXgaHUGI3q0hcAR8W3tOC+DwWgPKFpd7FPN0eoMRnNoVx44g8FYQeCCIwxG9GhbGhmDwVg5oEA1l9Q0BoPhBtbAI0Bvby+cffbZ/uexxx7zS5+GwWc/+1l48sknIxyh/jzlcln52ze/+U04//zzYdOmTXD22WfDO9/5Tvjxj38c+5h0+MQnPgEvvvhioH1uv/12v0Qro/3ggiMMRrRgDTwCrF27Fg4cOFD33d133x36eJ/97Gdh8+bNsGFDS0rEN+DgwYOwY8cO+NrXvub7KL/2ta/BY489BuPj47Gck/Iae3rUMuUnPvEJeNe73gX9/f2xnJ/BYDC6DStSA7/88qVPnEilUgCwpAVefvnl8Pa3vx02bdoEV199tV+u9L777oPZ2Vk499xzYW5uDp566im4+eabYf/+/XD11VfD2WefDS+99BIUCgV45plnAABg//79cPmpwX/kIx+B3/7t34bLL78czjjjDPjkJz/pn//zn/88nH/++XD22WfD+973Pr/O+Wc+8xn4lV/5FTj//PPhrrvuUo79z//8z+HDH/5wXYDRr//6r8PWrVsBYKn06Jve9CY499xz4bLLLoPvf38pC/Daa6+F3/3d34WLL74YzjjjDLj55pv9/T/2sY/BeeedB9PT03DDDTcAwFK51jPPPBPe/e53w+bNm+Hxxx+H+fl52LJlC0xNTfnbffKTn4Qnn3wStm3b5gdB3XbbbXDRRRfBOeecA+94xzvghRdeAIAly8GmTZvgnHPOgb/7u78Le/sixa5du2Dz5s3Q29sLmzdvhl27drV7SAwGYzlAV+GlEz9R9ANHRJydXfpEhZ6eHr91J7XlpFabi4uLmE6n8fHHH8cTJ07ghRdeiLt378Zjx47hRRddhD/96U8REfGLX/yi3/97dnYW7733Xv/4r371q/Hpp59GRMR7770XZ08N/oYbbsCLLroIX375ZXz66adxcHAQjx07hg8++CC+5S1v8fsEz8/P4+c+9zl88skncePGjfjTn/4Uf/nLX+LFF1/st+IU8frXvx4PHDigvd5f/dVfxYceeggREe+55x7ctm0bIurbp37rW9/C9773vXjy5Ek8ceIEvvnNb8Y77rgDH330UfQ8D/fu3esf+9lnn0VExFdeeQVnZ2f9Fq3iHDz99NN42WWX4QsvvICIiH/2Z3+GH/3oR/Gll17CfD6PDz30EJ48eRLf8Y534Jvf/GaHO2iH6TkzVRjjdpsMBqMZgKES24oyoZPWfccd9X/ffntzx1WZ0EWcf/75kM/nAQB8H3k2m4WDBw/CFVdcAQAAJ06cgNHR0cDnfvOb3wxr1qyBNWvWwPDwMPzkJz+B//t//y/cd999cN555wEAwEsvvQTDw8Pwj//4j3D55Zf7ddrf+c53wkMPPWQ8/rPPPgtveMMb4MUXX4Trr78e3v/+98Pdd98N73jHO/xtfvnLX/r/V7VPve222+C2227za6i/8MIL8IMf/ADGx8fh1a9+NVx44YX+/l/+8pfhU5/6FLzyyivw1FNPwYMPPgjT09N1Y7rnnnvgwQcfhEsuuQQAAI4dOwYXXXQRfP/734eJiQl47WuX6gS9613vgk996lOB5zQIdBXGAE43CqECJgDgFzDZsWMH+4AZDEZTWFEE3i6o2mgiIkxNTcHevXut+69atQpOnjwJAAAvv/yy07GvueYa+NM//dO6bW+99Van8U5NTcF3vvMdmJmZgVe96lVw4MAB+PjHPw4vvPACnDx5ErLZrFZgUbVPRUT40Ic+BO973/vqtn3sscfq2no++uij8PGPfxzuvfdeGBgYgGuvvbbheul4V1xxRYMp2iRExQUbQXMBEwaDERdWlA/89tuXPrOzSx/6ux0488wz4emnn/YJ/Pjx4/DAAw8AQH1bTACAQqEA9913HwAA/O3f/q312G94wxvg5ptvhp/+9KcAAHDkyBH40Y9+BBdccAHccccd8Oyzz8Lx48fhK1/5inL/P/iDP4CdO3fWkQxFgKfTaZiYmPD3RUS4//77jeOZm5uDT3/6076f+l/+5V/8sYn4+c9/DslkEjKZDPzkJz+Bf/iHf/B/E+fkwgsvhLvuugsefvhhAAD4xS9+AQ899BBs2rQJHnvsMfjhD38IANASX7ONoLndJoPBiAsrisA7CatXr4abb74Z/v2///cwMzMDZ599th+5fu2118L73/9+P4jthhtugA984AOwZcsW6O3ttR77rLPOgj/5kz+BN77xjTA9PQ1XXHEFPPXUUzA6Ogof+chH4KKLLoJLLrlESyKve93r4L/+1/8K7373u+HMM8+ESy65BA4dOgRXXXUVAIDf83xmZgampqbgq1/9qnE8b3zjG+Gqq66Ciy66CF73utfB29/+9joBhTAzMwOvf/3rYdOmTXDVVVf5JnIAgOuvvx7e9KY3wbZt22BoaAg++9nPwvbt22F6eto3nycSCfjUpz4Fb37zm+Gcc86B4eFh61w1CxtBcwETBoMRG3TO8U78RBXExmAEhe45cwlS4zaaDAYjLICD2BiMeOBSYWz79u0csMZgMCIHEziD0SSYoBkMRjvAPnAGg8FgMLoQy4LA8VS6EoMRB/j5YjAYnYiuJ/BEIgHPPvssL7KMWICI8Oyzz0IikWj3UBgMBqMOXe8Dz+fz8MQTT8DTTz/d7qEwlikSiYRfSY/BYDA6BV1P4H19fTAxMdHuYTAYDAaD0VJ0vQmdwWAwGIyVCCZwBoPBYDC6EEzgDAaDwWB0Ibxuit72PO9pAPhRzKdZDwDPxHyOdoGvrTvB19adWK7XtlyvC6Azr+3ViDik+qGrCLwV8DxvPyJuafc44gBfW3eCr607sVyvbbleF0D3XRub0BkMBoPB6EIwgTMYDAaD0YVgAm/Ep9o9gBjB19ad4GvrTizXa1uu1wXQZdfGPnAGg8FgMLoQrIEzGAwGg9GFYAJXwPO8P/Y873ue5x3wPO82z/M2tHtMUcHzvI95nvf9U9d3i+d52XaPKSp4nvcOz/Me8DzvpOd5XRNJqoPneW/yPO+fPc972PO8P2z3eKKE53mf9jzvp57nHWz3WKKE53kbPc9b9DzvwVPP4gfaPaao4HlewvO8fZ7n3X/q2j7a7jFFDc/zej3P+67neV9v91hcwASuxscQcRoRzwaArwPAH7V5PFHi/wDAZkScBoCHAOBDbR5PlDgIAL8BAHe2eyDNwvO8XgD4/wDg/wGAswBgu+d5Z7V3VJHiswDwpnYPIga8AgC/h4hnAcCFAPA7y+i+/RIAfhURZwDgbAB4k+d5F7Z3SJHjAwBwqN2DcAUTuAKI+HPhzyQALJtAAUS8DRFfOfXnPQCwbNpsIeIhRPzndo8jIpwPAA8j4iOIeAwAvggAb23zmCIDIt4JAEfaPY6ogYhPIeJ3Tv3/eVgig7H2jioa4BJeOPVn36nPslkbPc/LA8CbAeCv2z0WVzCBa+B53k7P8x4HgKtheWngIn4bAP6h3YNgKDEGAI8Lfz8By4QIVgo8zysAwOsB4B/bPJTIcMrEfAAAfgoA/wcRl821AcAnAOAPAOBkm8fhjBVL4J7nfdvzvIOKz1sBABCxgogbAeALAFBu72iDwXZtp7apwJK57wvtG2lwuFwbg9FueJ6XAoC/BYB/K1n0uhqIeOKUazEPAOd7nre5zUOKBJ7nvQUAfoqI97V7LEHQ9f3AwwIRf81x0y8AwN8DwA0xDidS2K7N87xrAeAtAPAG7LI8wgD3rdvxLwCwUfg7f+o7RofD87w+WCLvLyDi37V7PHEAEZ/zPG8RluIYlkMg4iUA8Oue5/0rAEgAQNrzvM8j4rvaPC4jVqwGboLnea8V/nwrAHy/XWOJGp7nvQmWzES/jogvtns8DC3uBYDXep434XneagD4TQD4WpvHxLDA8zwPAG4CgEOI+F/aPZ4o4XneEGWteJ63FgCugGWyNiLihxAxj4gFWHrXFjqdvAGYwHX4s1Nm2e8BwBthKTJxueC/AcA6APg/p9Lk/qrdA4oKnudd6XneEwBwEQB8w/O8b7V7TGFxKtCwDADfgqVAqC8j4gPtHVV08DxvFwDsBYAzPc97wvO869o9pohwCQD8FgD86qn368AprW45YBQAFk+ti/fCkg+8K9Ktliu4EhuDwWAwGF0I1sAZDAaDwehCMIEzGAwGg9GFYAJnMBgMBqMLwQTOYDAYDEYXggmcwWAwGIwuBBM4g7GC4XneiVOpTgc9z/uK53n9p74f8Tzvi57n/dDzvPs8z/t7z/N+RbH/suwqxmB0A5jAGYyVjZcQ8WxE3AwAxwDg/aeKkdwCALcjYhERz4WlrnU5xf6fheXZVYzB6His2FKqDAajAbsBYBoAtgHAcUT0i/wg4v2qHRDxzlNNOxgMRovBGjiDwQDP81bBUu/xfwKAzQDQVU0dGIyVCCZwBmNlY+2p9pD7AeDHsFTHm8FgdAHYhM5grGy8dKo9pA/P8x4AgLe3ZzgMBsMVrIEzGAwZCwCwxvO86+kLz/OmPc+7rI1jYjAYEpjAGQxGHU71iL8SAH7tVBrZAwDwpwBwWN52GXcVYzA6HtyNjMFgMBiMLgRr4AwGg8FgdCGYwBkMBoPB6EIwgTMYDAaD0YVgAmcwGAwGowvBBM5gMBgMRheCCZzBYDAYjC4EEziDwWAwGF0IJnAGg8FgMLoQ/z+/MlsvjmxZmQAAAABJRU5ErkJggg==\n" + }, + "metadata": { + "needs_background": "light" + } + } + ], + "source": [ + "plt.figure(figsize=(8, 5))\n", + "plt.scatter(X[:Klen, 0], X[:Klen, 1],\n", + " c='w', edgecolors='k', label='Known E. Coli inhibitors')\n", + "#plt.scatter(X[Klen:Klen + Flen, 0], X[Klen:Klen + Flen, 1],\n", + " # s=200, c='r', marker='2', edgecolors='k', label='Iteration 2 molecules')\n", + "plt.scatter(X[Klen + Flen:, 0], X[Klen + Flen:, 1],\n", + " c='b', marker='+', label='Finetuned Generated')\n", + "plt.xlabel('PC 1')\n", + "plt.ylabel('PC 2')\n", + "plt.legend();" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "UhWJHYsJ5jC-" + }, + "outputs": [], + "source": [ + "idxs = []\n", + "for Fbv in Fbvs:\n", + " idx = np.argmax(DataStructs.BulkTanimotoSimilarity(Fbv, Sbvs))\n", + " idxs.append(idx)\n", + "nsmols = [smols[idx] for idx in idxs]" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "RDIXRY0o9yOd" + }, + "outputs": [], + "source": [ + "showmols = []\n", + "for i, j in zip(fmols, nsmols):\n", + " showmols.append(i)\n", + " showmols.append(j)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 1000 + }, + "id": "aA4ygwVJF3Fh", + "outputId": "306174d2-5f22-420a-a483-c93fdaab8400" + }, + "outputs": [ + { + "output_type": "stream", + "name": "stderr", + "text": [ + "/usr/local/lib/python3.8/dist-packages/rdkit/Chem/Draw/IPythonConsole.py:258: UserWarning: Truncating the list of molecules to be displayed to 50. Change the maxMols value to display more.\n", + " warnings.warn(\n" + ] + }, + { + "output_type": "execute_result", + "data": { + "image/png": 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\n", + "text/plain": [ + "" + ] + }, + "metadata": {}, + "execution_count": 44 + } + ], + "source": [ + "Draw.MolsToGridImage(fmols)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/", + "height": 1000 + }, + "id": "I6I_d6DW9zSp", + "outputId": "8a9e7f23-95f7-4702-bd6f-2216fd2a8665" + }, + "outputs": [ + { + "output_type": "execute_result", + "data": { + "image/png": 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\n", + "text/plain": [ + "" + ] + }, + "metadata": {}, + "execution_count": 45 + } + ], + "source": [ + "\n", + "Draw.MolsToGridImage(showmols, molsPerRow=2)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "dwIQUTC192GY", + "outputId": "6082112a-e51c-4762-ca96-567eca692b3f" + }, + "outputs": [ + { + "output_type": "execute_result", + "data": { + "text/plain": [ + "['CN(C)CCCC1c2ccccc2Cc2ccccc21',\n", + " 'O=c1nc(-c2ccccc2Cl)c2cc(O)ccc2[nH]1',\n", + " 'CC(C)CCN1CCC(C)(c2ccccc2)c2ccccc21',\n", + " 'FC(F)(Cl)CCl',\n", + " 'ClC(Cl)Cl',\n", + " 'Cc1cnc2c(c1)C(c1ccccc1)=NCC(=O)N2',\n", + " 'CCc1ccc(CNC2=NC(=O)CC2)cc1',\n", + " 'CC(=O)C1c2ccccc2Oc2ccccc21',\n", + " 'C=CC1(CCCN(C)C)c2ccccc2C1c1ccccc1',\n", + " 'NCCc1ccccc1',\n", + " 'CN(C)CCCN1c2ccccc2C=Cc2ccccc21',\n", + " 'NC(Cl)(Cl)Br',\n", + " 'CCCN',\n", + " 'CC(N)=O',\n", + " 'O=C(c1cccnc1)N1CCOCC1',\n", + " 'CCc1ccccc1',\n", + " 'CCCC(=O)C1=CC=CNC1C(N)=O',\n", + " 'CN1CCN(C(=O)c2cccnc2)CC1',\n", + " 'CN(C)CCCC1C2=C(C=CC=Cc3ccccc31)C2',\n", + " 'CCNC1=NC2C=C(O)C=CC(Cc3ccc(Cl)cc31)C2',\n", + " 'CN(C)CCC(c1ccccc1)c1ccccc1',\n", + " 'Cc1ncsc1CCCl',\n", + " 'CCCC1CC(=O)NC1C',\n", + " 'CN(C)CCN1C2=NC=CC=Cc3ccc(Cl)cc3C21',\n", + " 'Cc1ccc(OCC2C(O)C2CC(C)C)cc1',\n", + " 'CN(C)CCOC(c1ccccc1)c1ccccc1',\n", + " 'CCC1(CC)C(=O)NC(=O)OC1=O',\n", + " 'C1CCCCC1',\n", + " 'CN(C)CCC1C2=C(C=CC=Cc3ccc(Cl)cc31)S2',\n", + " 'C=CCC1CCN(C(O)c2ccccc2)CC1',\n", + " 'Cc1csc(N=C(N)N)n1',\n", + " 'CCC(=O)Oc1ccc2c(c1)N(CCCN1CCN(CCO)CC1)c1ccccc1S2',\n", + " 'CN(C)CC=C1c2ccccc2C=Cc2ccccc21',\n", + " 'CCC(=O)O',\n", + " 'OC=NC1=C(c2ccccc2)CNC1',\n", + " 'CCC',\n", + " 'CCC(C)CC',\n", + " 'CN(C)CCCN1c2ccccc2Sc2ccccc21',\n", + " 'CCCCn1nc(N)nc1C(=O)O',\n", + " 'CCNCCCCc1cccnc1',\n", + " 'CCC(F)(F)C(F)(F)F',\n", + " 'O=C(O)Oc1ccccc1',\n", + " 'CCO',\n", + " 'CC(=O)C=CC(c1ccccc1)c1ccc(Cl)cc1',\n", + " 'CCCOC(N)=O',\n", + " 'CC1C(=O)CN=C(c2ccccc2Cl)c2cc(Cl)ccc21',\n", + " 'CCN',\n", + " 'CC(C)CCO',\n", + " 'CCN1CCN(CCCC2c3ccccc3Sc3ccc(C(F)(F)F)cc32)CC1',\n", + " 'CNC(C)C',\n", + " 'CC(C)(C=O)CO',\n", + " 'CC(O)C(F)(F)F',\n", + " 'CCc1ccccc1',\n", + " 'FC(F)(F)CCl',\n", + " 'CN(C)CCC1c2ccccc2Sc2ccccc21',\n", + " 'FC(F)(F)CC1(C(F)(F)Cl)CO1',\n", + " 'CCCCO',\n", + " 'C=CC(N)C1=CN=C(C)C1=O',\n", + " 'C#CCC',\n", + " 'Cc1ccccc1-n1ccc(C)c1CC1CCCCC1',\n", + " 'CC(C)CCOc1ccccc1',\n", + " 'C=C',\n", + " 'C=NCc1scnc1C',\n", + " 'C=CCC1(CC(C)C)C(=O)NC(=O)NC1=O',\n", + " 'CCNc1nccs1',\n", + " 'C=CCC1(CC)C(=O)NC(=O)NC1=S',\n", + " 'CCCC1C(=O)CC(c2ccccc2)C1=O',\n", + " 'CC1(C)CC(c2ccccc2)c2cc(O)c(C(=O)O)cc21',\n", + " 'CC(=O)C(c1ccccc1)c1ccccc1',\n", + " 'CC1C2=C(C=Cc3ccccc31)C(=O)OC2(C)C',\n", + " 'CCCCCC(=O)NO',\n", + " 'CCC1(O)C(=O)OC(=O)N(C)C1=O',\n", + " 'C1CC1',\n", + " 'ON1CCCOC(c2ccccc2)C1',\n", + " 'NNCC=C1c2ccccc2Sc2ccccc21',\n", + " 'CN(C)CC=C1c2ccccc2Sc2ccccc21',\n", + " 'COC1CCN(C)CCc2ccc(Cl)cc2N1c1ccccc1',\n", + " 'CN(C)CCC=C1c2ccccc2Sc2ccc(C(N)=O)cc21',\n", + " 'COCCCC(c1ccccc1)c1ccccc1',\n", + " 'CN1C(=O)CN=C(Br)c2cc(Cl)ccc21',\n", + " 'CC(C)OCC(=O)O',\n", + " 'C=CCCC(=O)C(C)c1ccccc1',\n", + " 'CC1C=NNC1=O',\n", + " 'CNc1c(C)cccc1Cl',\n", + " 'CC1CCCC1',\n", + " 'CC(C)CO',\n", + " 'C#CCNC(O)c1cccc(Br)c1',\n", + " 'FC(F)(F)C1=CC=CC=CC2CCN=CC12',\n", + " 'O=C1C2=CC=CC=CCCCC3CCC(CCC23)OC1C(F)(F)F',\n", + " 'CC(=O)N1C(=O)OC1Cc1ccccc1',\n", + " 'Cc1ccccc1',\n", + " 'CC1CCCC1',\n", + " 'OCCN1CCN(CCC2c3ccccc3Sc3ccc(Cl)cc32)CC1',\n", + " 'CCC1=CC=C(C)C1',\n", + " 'CC1(C)Cc2ccccc2N(N)c2ccccc21',\n", + " 'C=C(N)N(C)Cc1ccccc1',\n", + " 'CC(Cc1ccccc1)OC(=O)O',\n", + " 'CC(C)C(=O)CC(c1ccccc1)c1ccccc1',\n", + " 'CC(F)(F)Cl',\n", + " 'O=C(NCC(O)c1ccccc1O)c1ccccc1C=Cc1ccc(Br)cc1']" + ] + }, + "metadata": {}, + "execution_count": 46 + } + ], + "source": [ + "finetuned_smiles" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "Lu9sflXWbS3x" + }, + "outputs": [], + "source": [ + "with open('bbbp_gen_norm_22.txt', 'w') as f:\n", + " for line in finetuned_smiles:\n", + " f.write(f\"{line}\\n\")" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "colab": { + "base_uri": "https://localhost:8080/" + }, + "id": "pQber6TMbk_Z", + "outputId": "205b43c5-6521-42cb-f1d6-86879401a3a0" + }, + "outputs": [ + { + "data": { + "text/plain": [ + "100" + ] + }, + "execution_count": 80, + "metadata": {}, + "output_type": "execute_result" + } + ], + "source": [ + "len(finetuned_smiles)" + ] + }, + { + "cell_type": "code", + "execution_count": null, + "metadata": { + "id": "bwCBBHui7i4a" + }, + "outputs": [], + "source": [] + } + ], + "metadata": { + "accelerator": "GPU", + "colab": { + "provenance": [] + }, + "gpuClass": "standard", + "kernelspec": { + "display_name": "Python 3", + "name": "python3" + }, + "language_info": { + "name": "python" + } + }, + "nbformat": 4, + "nbformat_minor": 0 +} \ No newline at end of file diff --git a/lstm_chem/__init__.py b/lstm_chem/__init__.py new file mode 100644 index 0000000000000000000000000000000000000000..8b137891791fe96927ad78e64b0aad7bded08bdc --- /dev/null +++ b/lstm_chem/__init__.py @@ -0,0 +1 @@ + diff --git a/lstm_chem/data_loader.py b/lstm_chem/data_loader.py new file mode 100644 index 0000000000000000000000000000000000000000..8b2a34ce6d52619e1aa369adeb8207b235e77de9 --- /dev/null +++ b/lstm_chem/data_loader.py @@ -0,0 +1,123 @@ +import json +import os +import numpy as np +from tqdm import tqdm +from tensorflow.keras.utils import Sequence +from lstm_chem.utils.smiles_tokenizer2 import SmilesTokenizer + + +class DataLoader(Sequence): + def __init__(self, config, data_type='train'): + self.config = config + self.data_type = data_type + assert self.data_type in ['train', 'valid', 'finetune'] + + self.max_len = 0 + + if self.data_type == 'train': + self.smiles = self._load(self.config.data_filename) + elif self.data_type == 'finetune': + self.smiles = self._load(self.config.finetune_data_filename) + else: + pass + + self.st = SmilesTokenizer() + self.one_hot_dict = self.st.one_hot_dict + + self.tokenized_smiles = self._tokenize(self.smiles) + + if self.data_type in ['train', 'valid']: + self.idx = np.arange(len(self.tokenized_smiles)) + self.valid_size = int( + np.ceil( + len(self.tokenized_smiles) * self.config.validation_split)) + np.random.seed(self.config.seed) + np.random.shuffle(self.idx) + + def _set_data(self): + if self.data_type == 'train': + ret = [ + self.tokenized_smiles[self.idx[i]] + for i in self.idx[self.valid_size:] + ] + elif self.data_type == 'valid': + ret = [ + self.tokenized_smiles[self.idx[i]] + for i in self.idx[:self.valid_size] + ] + else: + ret = self.tokenized_smiles + return ret + + def _load(self, data_filename): + length = self.config.data_length + print('loading SMILES...') + with open(data_filename) as f: + smiles = [s.rstrip() for s in f] + if length != 0: + smiles = smiles[:length] + print('done.') + return smiles + + def _tokenize(self, smiles): + assert isinstance(smiles, list) + print('tokenizing SMILES...') + tokenized_smiles = [self.st.tokenize(smi) for smi in tqdm(smiles)] + + if self.data_type == 'train': + for tokenized_smi in tokenized_smiles: + length = len(tokenized_smi) + if self.max_len < length: + self.max_len = length + self.config.train_smi_max_len = self.max_len + print('done.') + return tokenized_smiles + + def __len__(self): + target_tokenized_smiles = self._set_data() + if self.data_type in ['train', 'valid']: + ret = int( + np.ceil( + len(target_tokenized_smiles) / + float(self.config.batch_size))) + else: + ret = int( + np.ceil( + len(target_tokenized_smiles) / + float(self.config.finetune_batch_size))) + return ret + + def __getitem__(self, idx): + target_tokenized_smiles = self._set_data() + if self.data_type in ['train', 'valid']: + data = target_tokenized_smiles[idx * + self.config.batch_size:(idx + 1) * + self.config.batch_size] + else: + data = target_tokenized_smiles[idx * + self.config.finetune_batch_size: + (idx + 1) * + self.config.finetune_batch_size] + data = self._padding(data) + + self.X, self.y = [], [] + for tp_smi in data: + X = [self.one_hot_dict[symbol] for symbol in tp_smi[:-1]] + self.X.append(X) + y = [self.one_hot_dict[symbol] for symbol in tp_smi[1:]] + self.y.append(y) + + self.X = np.array(self.X, dtype=np.float32) + self.y = np.array(self.y, dtype=np.float32) + +# return self.X, self.y, [None] + return self.X, self.y + + def _pad(self, tokenized_smi): + return ['G'] + tokenized_smi + ['E'] + [ + 'A' for _ in range(self.max_len - len(tokenized_smi)) + ] + + def _padding(self, data): + padded_smiles = [self._pad(t_smi) for t_smi in data] + return padded_smiles diff --git a/lstm_chem/finetuner.py b/lstm_chem/finetuner.py new file mode 100644 index 0000000000000000000000000000000000000000..24f26ce3bcebef8b6a787258980a749ff9d48862 --- /dev/null +++ b/lstm_chem/finetuner.py @@ -0,0 +1,25 @@ +from lstm_chem.utils.smiles_tokenizer2 import SmilesTokenizer +from lstm_chem.generator import LSTMChemGenerator + + +class LSTMChemFinetuner(LSTMChemGenerator): + def __init__(self, modeler, finetune_data_loader): + self.session = modeler.session + self.model = modeler.model + self.config = modeler.config + self.finetune_data_loader = finetune_data_loader + self.st = SmilesTokenizer() + + def finetune(self): + self.model.compile(optimizer=self.config.optimizer, + loss='categorical_crossentropy') + +# history = self.model.fit_generator( + history = self.model.fit( + self.finetune_data_loader, + steps_per_epoch=self.finetune_data_loader.__len__(), + epochs=self.config.finetune_epochs, + verbose=self.config.verbose_training, + use_multiprocessing=True, + shuffle=True) + return history diff --git a/lstm_chem/generator.py b/lstm_chem/generator.py new file mode 100644 index 0000000000000000000000000000000000000000..4f80e9fde3f03e96a47552fae7e756430c5c095f --- /dev/null +++ b/lstm_chem/generator.py @@ -0,0 +1,44 @@ +from tqdm import tqdm +import numpy as np +from lstm_chem.utils.smiles_tokenizer2 import SmilesTokenizer + + +class LSTMChemGenerator(object): + def __init__(self, modeler): + self.session = modeler.session + self.model = modeler.model + self.config = modeler.config + self.st = SmilesTokenizer() + + def _generate(self, sequence): + while (sequence[-1] != 'E') and (len(self.st.tokenize(sequence)) <= + self.config.smiles_max_length): + x = self.st.one_hot_encode(self.st.tokenize(sequence)) + preds = self.model.predict_on_batch(x)[0][-1] + next_idx = self.sample_with_temp(preds) + sequence += self.st.table[next_idx] + + sequence = sequence[1:].rstrip('E') + return sequence + + def sample_with_temp(self, preds): + streched = np.log(preds) / self.config.sampling_temp + streched_probs = np.exp(streched) / np.sum(np.exp(streched)) + return np.random.choice(range(len(streched)), p=streched_probs) + + def sample(self, num=1, start='G'): + sampled = [] + if self.session == 'generate': + for _ in tqdm(range(num)): + sampled.append(self._generate(start)) + return sampled + else: + from rdkit import Chem, RDLogger + RDLogger.DisableLog('rdApp.*') + while len(sampled) < num: + sequence = self._generate(start) + mol = Chem.MolFromSmiles(sequence) + if mol is not None: + canon_smiles = Chem.MolToSmiles(mol) + sampled.append(canon_smiles) + return sampled diff --git a/lstm_chem/model.py b/lstm_chem/model.py new file mode 100644 index 0000000000000000000000000000000000000000..368a834b393887ca7f6f72bf06fc886f0e9ba1ee --- /dev/null +++ b/lstm_chem/model.py @@ -0,0 +1,73 @@ +import os +import time +from tensorflow.keras import Sequential +from tensorflow.keras.models import model_from_json +from tensorflow.keras.layers import LSTM, Dense +from tensorflow.keras.initializers import RandomNormal +from lstm_chem.utils.smiles_tokenizer2 import SmilesTokenizer + + +class LSTMChem(object): + def __init__(self, config, session='train'): + assert session in ['train', 'generate', 'finetune'], \ + 'one of {train, generate, finetune}' + + self.config = config + self.session = session + self.model = None + + if self.session == 'train': + self.build_model() + else: + self.model = self.load(self.config.model_arch_filename, + self.config.model_weight_filename) + + def build_model(self): + st = SmilesTokenizer() + n_table = len(st.table) + weight_init = RandomNormal(mean=0.0, + stddev=0.05, + seed=self.config.seed) + + self.model = Sequential() + self.model.add( + LSTM(units=self.config.units, + input_shape=(None, n_table), + return_sequences=True, + kernel_initializer=weight_init, + dropout=0.3)) + self.model.add( + LSTM(units=self.config.units, + input_shape=(None, n_table), + return_sequences=True, + kernel_initializer=weight_init, + dropout=0.5)) + self.model.add( + Dense(units=n_table, + activation='softmax', + kernel_initializer=weight_init)) + + arch = self.model.to_json(indent=2) + self.config.model_arch_filename = os.path.join(self.config.exp_dir, + 'model_arch.json') + with open(self.config.model_arch_filename, 'w') as f: + f.write(arch) + + self.model.compile(optimizer=self.config.optimizer, + loss='categorical_crossentropy') + + def save(self, checkpoint_path): + assert self.model, 'You have to build the model first.' + + print('Saving model ...') + self.model.save_weights(checkpoint_path) + print('model saved.') + + def load(self, model_arch_file, checkpoint_file): + print(f'Loading model architecture from {model_arch_file} ...') + with open(model_arch_file) as f: + model = model_from_json(f.read()) + print(f'Loading model checkpoint from {checkpoint_file} ...') + model.load_weights(checkpoint_file) + print('Loaded the Model.') + return model diff --git a/lstm_chem/tokenizer_bpe.json b/lstm_chem/tokenizer_bpe.json new file mode 100644 index 0000000000000000000000000000000000000000..2634e6550395dca716680b98455dc389a6818fb3 --- /dev/null +++ b/lstm_chem/tokenizer_bpe.json @@ -0,0 +1,5965 @@ +{ 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"Nc3ccccc3 C", + "CCS 1", + "CCCO c1cccc", + "nc4 c3", + "1 ccc", + "c7 cc", + "cc4 Cl", + "c4nc5 ccccc5", + "c2cccnc2 1", + "O OC", + "3 CCC4", + "ccc3 F", + "CC5 CC", + "c4 F", + "CCC N2C", + "N c1cnc", + "Nc1cc n", + "n1 Cc1ccccc1", + "Br c1ccc", + "CC P", + "c2 cc1C", + "CO c2c", + "C n3c", + "CS C2", + "10 ccccc", + "CC2 CCCO2", + "C4 CCN", + "10 c", + "nc5 4", + "c6 cc7", + "s c6ccccc6", + "C5 C", + "NCc2ccc o2", + "CCOC 1CC", + "c3cc sc3", + "C5 CC5", + "n4 C", + "ccc3 Cl", + "N c2nccc", + "C2 S", + "ccc3 ccccc23", + "ncc2 c", + "c4ccc o4", + "o c2c", + "OC1 CCCCC1", + "B 2OC", + "N1 CCO", + "C 8", + "oc 7ccccc7", + "n 8", + "Nc1ccccc1 F", + "N 6", + "c1 3", + "CC1 NC", + "OCC S", + "c2ccccc2 S", + "Nc1ccccc1 Cl", + "CCCC COC", + "Cc1ccccc1 N", + "cc4 5", + "c1nccc n1", + "c2ncc n2C", + "c1cc2ccccc2 o1", + "Cc1ccc 2cc", + "Cc1ccc2 ccccc2c1", + "c1ccc2 oc", + "CC2 CN", + "c5cccc6 ccccc56", + "Cc2cc ncc2", + "B 3", + "ccc3 cc", + "CN c2nc", + "M g", + "SC c2ccc", + "CCCC l", + "c3nc4 ccc", + "CC c1cnc", + "CCC1 2", + "s c2C", + "1 2O", + "N1CC c2cc", + "CCn1 ncc", + "CCC NC1", + "CC2 C1", + "CN c1cccc", + "CCC N1CCC", + "OC 5", + "c1cc ccc21", + "N1 C2", + "CCc1cc 2c", + "CCC OCC", + "Cc1cccc 2ccccc12", + "c4ccccc4 n", + "1 c1cccc", + "o c3c", + "O c2ccc3c", + "c5ccccc5 n6", + "c1ncc cc1C", + "cc2 c1C", + "3 CO", + "O c3c", + "CCC1 CCCCC1", + "c1ccccc1 n2", + "c6 5", + "CN1 CCCN", + "O c1ccccc1C", + "c3ccccc3 N", + "c6 ccccc56", + "CN CC1", + "c3ccccc3 n4", + "N2 c2ccc", + "N1 c1ccccc1", + "ccc1OC c1ccc", + "CCS C1", + "C o", + "cc1 CNC", + "c3nc4ccccc4 s3", + "ccccc3 2", + "c1n nnn1", + "c nc12", + "c1cc2 ccc", + "Nc1c nn", + "cccc3 C", + "F c1c", + "C3 4", + "CN3 CCOCC3", + "c3nc nc", + "CCc1ccccc1 NC", + "OC c4ccc", + "G e", + "R u", + "C c2n", + "nnc1 SCC", + "N c4cccc", + "C2CCC N2C", + "ccc2 Br", + "NCC c1c", + "C1CCC NC1", + "N i", + "CN CCN", + "Cc1nc sc1", + "2 CCCC2", + "CS c2ccc", + "Cc1n ccn1", + "N CCN1C", + "CO CCN1", + "nc4 ccc", + "CCOc1ccccc1 NC", + "c2ccccc2 n3", + "C1 c2ccccc2", + "n2 c3ccc", + "c2cn c3c", + "OCCO 1", + "O c3cccc", + "c3 c2C", + "C1 Cc2ccccc2", + "ccccc2 1", + "n1 C1CC1", + "CCCC 1C", + "cccc1 NC", + "CN1 CCC2", + "c2nc3ccccc3 c", + "CO CCCN", + "o c2ccc", + "Nc1cc 2c", + "n4 ccc", + "c5 nc6", + "NC 5", + "OC O5", + "CCS C2", + "ccc3 OC", + "ncc2 C", + "2CCC N2", + "N N2C", + "C3 CCCC", + "c2 cc1", + "CCCCCCCCCCCCCCCC CCCCCC", + "CCO c1ccccc1C", + "Cc1cc 2cc", + "c3 o", + "nc1 CC", + "NC c2c", + "ccc3 C2", + "c nc21", + "n1c nc2c", + "ccc2 s1", + "nc5 c", + "c1nc nc", + "C c4cc", + "2 CNC", + "c2 s1", + "OCC 4", + "Cc1c s", + "CCO CCN", + "o c3c2", + "cccc3 F", + "cc2cc ccc12", + "Nc1ccc nc1", + "c2ncccc2 C", + "C c5ccccc5", + "c5ccccc5 n", + "nc4 cc", + "C1 CCNC1", + "ccc nc23", + "n s", + "CC2 CCN", + "c3 c1", + "n cc12", + "C1 c1cccc", + "S c3ccc", + "COC c1ccc", + "n c3ccccc3c2", + "Nc1n c2ccc", + "N1 Cc1ccccc1", + "ccc5 c4", + "Cl c1cc", + "c4ccc5 c6ccccc6", + "OC2 CCN", + "CO CCOCCO", + "c3 s2", + "7 C", + "n3c nc4c", + "n1nn nc1", + "cc2 NC", + "CCNC c1ccc", + "Cc3ccc nc3", + "o n3", + "c7ccccc7 6", + "3 CCCO3", + "c1 CNC", + "c nn3", + "c2 Br", + "CCCC CCO", + "c3nc n", + "C2CCC N2", + "3 CCOCC3", + "2 c2ccccc2", + "O c2nc", + "cccc 6", + "CN 5", + "COC c1cc", + "S OO", + "N1CC c2ccccc2C1", + "nc2 c1C", + "c2 o1", + "CCC NCC", + "CN c1ncc", + "COC 1CC", + "N c2ccc3", + "n2 1", + "OC 2CC", + "Cl c1cccc", + "Cn1 nnc", + "cn1 C", + "CNC1 CC1", + "1CCCC N1C", + "c5cccc n5", + "N5 CCN", + "CCCN S", + "o c2C", + "3 4C", + "C3 CCOCC3", + "n1 n", + "] (=", + "4 C3", + "c3cc n", + "nc3 n", + "C c3ccc4c", + "P 1", + "CC4 C", + "CCCNC 3", + "CN c1c", + "c5c nc", + "c1 C2", + "C B", + "CCCC COc1ccc", + "Cc3ccc o3", + "c2cc oc2", + "cc1 3", + "1 5", + "CS c2nc", + "N N2", + "C4 3", + "CC2 CCCC2", + "CS c1ccccc1", + "ccccc2 4", + "C2 CC3CC", + "C1 CNC1", + "CCCC CCNC", + "-] #", + "OCC2 CC2", + "cc2 N1", + "OC c2c", + "OC1 CCN", + "CN3 CCCC3", + "c sc1", + "CC1 2CCC", + "c4ccccc4 F", + "CCS c1ccc", + "2 CCCCC2", + "COC 1C", + "cc1 C1", + "N O1", + "c1cccc2 cccnc12", + "CCCC Cc1ccc", + "c3ncc s3", + "C1 2C", + "C4 O", + "ccc3 o2", + "cc1 NS", + "c3cc4 cc", + "c2 4", + "C5 CC", + "9 c", + "C c4cccc", + "c5 c6", + "CC1 CCC2", + "SiH 3", + "c2ncc cc12", + "1 OCc1ccccc1", + "nc2s c3c", + "c1ncc n1C", + "CS c1cc", + "CO 4", + "3 NC", + "2 CS", + "CCO c1ccc2c", + "c6cccc7 c6", + "sc2c1 CCCC2", + "CCCN c1cc", + "n1cc cc1", + "c3n ccc", + "ccc1 n2", + "C1CCCC CC1", + "OC2 CCCC2", + "OC1 OC", + "N2 c3ccccc3", + "cc2 o1", + "C3 N", + "c4c5ccccc5 c", + "2 CCS", + "c9 ccc", + "c1cccc 3", + "N n2c", + "Cc1cc2 nc", + "oc5ccccc5 6", + "c6ccc7 ccccc7", + "N1 Cc1ccc", + "CCCCCCCCCCCCCCCC CCCCCCCC", + "1 c1cc", + "cc3 c3cc", + "CC3 CCC", + "1 c1ncc", + "CCC N1CCN", + "CCC1 2C", + "n3 ncc", + "CC F", + "CCN2 CCOCC2", + "c nc3", + "ccc4 c", + "3 CC4CC", + "n2 n", + "Nc2ccccc2 F", + "CCCC CCC1", + "1C c2ccccc2", + "n c2n", + "CCCCCCCCCCCCCCCC CCCCCCC", + "c1 C1", + "R b", + "1CC c2c", + "Cc1ccccc1 OC", + "NC1 CCCN", + "CCS 2", + "c1cc2 cccc", + "s c4", + "c5 ncc", + "11 c", + "c2ccccc2 NC", + "c7cccc 8", + "NCC c2ccccc2", + "no c2C", + "c1n nc2n1", + "n2c nc", + "CN1 CC2", + "c1csc n1", + "c1ccc2 ccc", + "NCCC OC", + "N1CC c2ccccc21", + "c1cnc nc1", + "OCC1 OC", + "CCO c1nc", + "C c3ccccn3", + "c2nc3ccccc3 o2", + "c1cc2 nc", + "Cc1n ccc", + "N1CC c2sccc2", + "N2 CCNC", + "CCO CCC", + "Nc1ccc2 nc", + "cc n4", + "c2 O1", + "CCS CC", + "COc1ccccc1 N1CCN", + "c1cn n2", + "C n2ccnc2", + "C3 CCC4", + "NC3 CCC", + "C c4c", + "CCCO c1c", + "3 N", + "c2s cc", + "c2cc3 ccc", + "c5cc6 ccccc6", + "CN 3CC", + "NC1 CCCCCC1", + "c5ccc nc5", + "O c2ccccc21", + "COC 1CCC", + "CO CCOc1ccc", + "n2c nnn2", + "Nc2ccccc2 Cl", + "O CCC2", + "nc 7", + "CN2 CCC3", + "NCC1 CCCO1", + "OCCC OC", + "c4 O", + "n s1", + "c4ccccc4 Cl", + "@@ +]([", + "c2n o", + "c2ccc3 ccc", + "s e", + "c1ccc 3", + "C3CCN CC3", + "CCO CCOC", + "CNC 1CCC", + "CCC c2ccccc2", + "@ +]([", + "cc cc1OC", + "c7ccccc7 n", + "S c2cc", + "c2ccc 2", + "C2 CCS", + "N2 CCO", + "Nc1ncc s1", + "NC c2cccnc2", + "B 2", + "NH 4", + "c3ccc4 nc", + "c3ccccc3 c", + "S c2nnc", + "n2 ncc3", + "5 OC", + "NC c1cn", + "cc3 O", + "CCCC CCOc1ccc", + "c4 nccc", + "COC1 CCN", + "C3 CCC2", + "ncc2 3", + "CCC1 O", + "N5 CCOCC5", + "Nc1cc nc", + "C4 CCCC4", + "Cc1cc2 ccccc2", + "F c1ccccc1", + "ccc2 N1", + "c1 c2cc", + "c6ccc7ccccc7 c6", + "s c23", + "C a", + "cc 9", + "c2ccc nc12", + "Cc3ccccc3 F", + "CCC n1nc", + "sc 7ccccc7", + "O c4cc", + "N3CCCC CC3", + "C2 CCC3", + "N c2cn", + "N2CC c3ccccc3C2", + "NCC1 CN", + "O CCCCCCCCCCCC", + "nc nc43", + "Cc3ccc s3", + "CCC1 N", + "c1ccc2 ccccc2n1", + "C1 COC", + "c3cc ccc13", + "c2nc3ccccc3 n2", + "OC2 CCC", + "c1nc2ccccc2 o1", + "NC2 CCCC", + "6 OC", + "c2ccc3ccccc3 n2", + "c1ncc n1", + "COc1cc nc", + "NC c3cccc", + "c1OC c1ccccc1", + "CCS CC1", + "c1ccccc1 OCC", + "CCCC1 CC", + "S c3ccccc3", + "CCCCCCCC N", + "c o2", + "s c2c", + "NCC 4", + "NCC1 CCCCC1", + "C c2nnc", + "no c1C", + "H 2", + "CN c2cccc", + "OC O", + "ccc3 O", + "C1 CCCO1", + "c3ccccc3 n", + "CCn1 ccc", + "c2cccc3 c2o", + "N c5ccc", + "n4 nc", + "N c2ccccc21", + "3 CCCC3", + "ccc 8", + "cc5 c4", + "cc4 C3", + "CCCC CN1C", + "c4 nnc", + "n3 2", + "s c3n2", + "NC c2ccc3c", + "C1 CCCC2", + "4 CCCC", + "3 COC", + "nc3 sc", + "CCO S", + "n2nn nc2", + "N1 CCNC", + "CN CCCC", + "NC c1ccnc", + "NCc1ccc s1", + "sc4ccccc4 5", + "C3 CN", + "N n1c", + "CCCN 3C", + "N2 1", + "c1cc 3c", + "c1cc2 n", + "C c5ccc", + "N c2sc3c", + "Nc1s c2c", + "CNC1 CCN", + "CCCC CCOC", + "n1c ncn1", + "cc3 c1", + "N N1C", + "CO CC2", + "1 F", + "c5cc6 c", + "1 CCO", + "c2ccccc2 c1C", + "c4cccc5c4 oc4ccccc45", + "c1cc2 c3c", + "N3 CCC4", + "CN1 C2", + "c3nc4 cc", + "Cn1n ccc1", + "c4c ncc", + "N OCC", + "c7ccc8 c", + "c3cncc n3", + "NC1 CC2", + "CCC1 CCCC1", + "N2CCCC 2C", + "CC n2c", + "3 2C", + "n4c nc5c", + "nn1 CC", + "CCC OC1", + "CC c1cn", + "OC c1cccc", + "CCN1 CCCCC1", + "S c1nc", + "c1nc2ccccc2 n1", + "N2 N", + "2 CN1C", + "c1ccc2 c3c", + "O c3", + "NC3 CCCC3", + "CCCO 4", + "NCC2 CCCO2", + "CC1 CS", + "N3 CC4", + "C2 CCCO2", + "C1 CNC", + "c nn", + "NC1 CN", + "n3 cccc3", + "CC3 CCCCC3", + "cc2 c1O", + "CCN2 CCN", + "Cc1c nc2c", + "c3 OC", + "n3c nn", + "O CCCNC", + "C2CCC NC2", + "5 c", + "NC c1ccccn1", + "CCOc1cc 2c", + ")( /", + "s c21", + "C2 CCOC2", + "N2CC c3ccccc32", + "S CC2", + "Cc1cccc 2c", + "c2cc3ccccc3 o2", + "Nc1nc nc2c1ncn2", + "NC3 CCN", + "Cc3ccccc3 Cl", + "cnc1 N", + "c5ccccc5 C", + "N5 C", + "1 CCOC1", + "cc2 S", + "C c2ncc", + "CCC 6", + "C c3nc", + "CC3 C2", + "c2cc3 nc", + "CC c1", + "CCCCCCCCCCCCCCCC CCCCCCCCC", + "OC2 CCCCC2", + "NCC1 CC1", + "CC c1noc", + "CS c2n", + "n nc1C", + "c4cc nc", + "cc4 s3", + "n2 N", + "c1cc 3", + "n2 c3c", + "C3 OC", + "Cc1ccccc1 O", + "Nc1cccc 2ccccc12", + "c3 1", + "cn2 C", + "Nc1cccc n1", + "A s", + "CCCO c1ccccc1", + "4 CCOCC4", + "Nc2cc cc3", + "c2 c34", + "c1c n2c", + "c n5", + "COC c3ccccc3", + "n3 ccccc3", + "CS Cc1ccc", + "CCCCCCCC OC", + "nc nc2", + "c8 cccc", + "COc1ccccc1 CNC", + "CNC c2ccc", + "CCNC c1cc", + "+] /", + "CC1CCN CC1", + "NCCN1 CCOCC1", + "S CCN", + "c8 c", + "c2cccc 4", + "F F", + "NCC2 CCC", + "1 OCC", + "c3nn nn3", + "CCO CCCNC", + "4 CCN", + "n6c7ccccc7 c7ccccc76", + "N c2nc3c", + "CCC1 CC1", + "CC12 CC3CC", + "c2cccc3 c", + "3CCCN 3C", + "CCC1 NC", + "c2cnc nc2", + "1 8", + "n2c nnc2", + "C1CC1 C", + "N CCOc1ccc", + "cc2 nc", + "B 3OC", + "n3 c4ccc", + "cc1 CO", + "CCN1 CCCC", + "c1cnc s1", + "ccc3 1", + "1CCC NC1", + "COc1cc2 nc", + "9 ccccc9", + "CCCC CC3", + "1 n", + "N1 CCCC2", + "cccc3 4", + "c nc32", + "c3ccccc3 O2", + "S C3", + "o c3ccc", + "Cn1c nc2c", + "c4ccccc4 c3", + "COC c1nc", + "ncc1 Br", + "o 5", + "CO c1cnc", + "oc 7", + "NCCC 3", + "OCCO CC", + "o c4", + "NC c1nnc", + "cc2 O1", + "O c1nc", + "c2c nc3", + "OC c5ccccc5", + "2 SC1", + "NCC c1nc", + "nc4 ccccc34", + "c2 c3", + "NCC2 CC2", + "ccccc4 3", + "c2nc nc3", + "S c1cccc", + "cc1 C2", + "CCOC 1C", + "CCCC CCCN", + "CC c2cccc", + "NC4 CC4", + "c6ccccc6 n7", + "c3ncc cc23", + "5 4", + "cc3 ccccc3", + "ccc4 C", + "Nc2nc nc", + "O CCCO3", + "2 CC3", + "4 ccccc4", + "nc2 Cl", + "c6cccc7 ccccc67", + "C2 3CC", + "ccc2 c3", + "ccn1 2", + "1C c1ccccc1", + "CO NC", + "CN3 CCCCC3", + "N CCCCN", + "Nc1cc 2", + "c2 c1nc", + "NC N", + "Nc2c nn", + "CC1 CCOCC1", + "CO CCC1", + "Cc1o nc", + "O c2ncc", + "Cl c1nc", + "c7 nc", + "CO CCOCC", + "3 CCCCC3", + "Cn2 nn", + "COC c1cccc", + "NC c4ccc", + "CC1CCCC N1", + "n nc12", + "CO c3cc", + "Cc1n o", + "c1cccc 2cc", + "CCCN 5C", + "1 S", + "ccc2 n3", + "c4 nn", + "c3cccc4c3 oc3ccccc34", + "2 3CC", + "c2cc3 c4c", + "c2ccccc2 C3", + "N CCN1CCN", + "CC4 CC4", + "OC1 CCCCO1", + "CC 7", + "c nc1C", + "c2s ccc2C", + "CCCC N1", + "CCc1ccc s1", + "Cc2ccccc2 C1", + "F C1", + "c3s c4c", + "OC3 OC", + "NCC SC", + "c1cccc2 c1C", + "C12 CCN", + "NCC c1cccc", + "Cn1c ncn1", + "Cc1ccccc1 S", + "ccc4 5", + "S c2nc", + "o c4ccc", + "CCCO c2ccc", + "OC c3c", + "OC c2nc", + "OC1 CC2", + "CN2 CCC1CC2", + "CN1CCN CC1", + "CC1CCC N1C", + "c1s cc", + "NC1 CCS", + "c1n sc", + "c2ccc3 c4c", + "Cn1nn nc1", + "c1ccc 3c", + "COC 4", + "NCCC S", + "CO c2ccc3c", + "Cn1 c2ccccc2", + "CCCCC1 C", + "nc4 5", + "c2csc n2", + "cc3 c2c1", + "NC c3ccco3", + "c5nc6 ccccc6", + "COCCO CCNC", + "CS c3nnc", + "CCC2 C1", + "c1 c2", + "OC c3cccc", + "c3cccc n23", + "o c1c", + "cc2 c1OC", + "CCCC CC1CCC", + "CCO 4", + "cn2 3", + "SC c3ccc", + "C1CCCC N1C", + "n cc1Cl", + "c4nc5 c", + "n3c4ccccc4 c4", + "S c2cccc", + "c9 c", + "N c2ccccn2", + "Cc2cc cc3ccccc23", + "N1 c1cccc", + "Cl C", + "c3ccc4 ccc5", + "] %", + "cccc1 3", + "nc4ccccc4 3", + "o c4cc", + "CCN 2CCC", + "] =", + "4 CCCN", + "ccc1 CN", + "c nc2c1", + "Nc1nc nc", + "c5c4 3", + "CNC 1C", + "Cc1ccc2 oc", + "c3cccc4 c3s", + "ccc2 ccc", + "Cn1ccc n1", + "CCC Br", + "CCN3 CCOCC3", + "c nn2C", + "Cc2cc sc2", + "NC2 CCCCCC2", + "Nc1ccccc1 OC", + "M n", + "c2n nc3n2", + "C2CC2 C", + "1 2c", + "CN4 CCN", + "C2 c3c", + "sc1 Cl", + "CNC 1CC", + "OC1 2CC3CC", + "CCCS 2", + "N c3n", + "c3cc oc3", + "n ccc12", + "C n3nc", + "n n2c", + "sc2 C1", + "N1CCCCC1 C", + "c3ncc cc3", + "Cc1ccccc1 CN", + "CCCC c1cc", + "N c1nn", + "N2 CCS", + "C1CCCC N1", + "CC3 2", + "CC1 2C", + "c nc23", + "nc3s c4c", + "ncc2 Cl", + "nn2 c1", + "CCC N1CC", + "n1 nnc", + "sc1 Br", + "n7 c8ccccc8", + "C1CC2 CCC1C2", + "S c1cc", + "OC1 C2CC3", + "3 C4", + "CCN c1ncc", + "COc1ccccc1 N", + "Cc1ccccc1 Br", + "CCOC 4", + "ccc6 5", + "C2CCCC CC2", + "OC 3CC", + "c4nccc n4", + "CCO c2ccccc2", + "n2c3ccccc3 c3ccc", + "S CC1", + "+] .", + "Nc2ncc s2", + "CC c2ccccc21", + "CC c3c", + "SC c2ccccc2", + "S CCNC", + "CS c1ncc", + "CCCNC c1ccc", + "NC1 2CC3CC", + "s c3nc", + "NCC2 CCN", + "s c2nc", + "c2ncccc2 1", + "c4ccccc4 c", + "n3 4", + "cc5 c", + "c1c nc2", + "C c3ccncc3", + "o nc", + "c2c oc", + "cc5 C", + "C5 CCC", + "CO c4ccc", + "O c5ccc", + "CCCC c1nc", + "c5 C", + "c nc2n1", + "N c2cnc", + "CCC 3C", + "c5cc ncc5", + "CCN1 CC2", + "c2cccc3 cccnc23", + "CCCCCC c1ccc", + "2 CCOC2", + "NCCO CC", + "CNC c1cccc", + "C r", + "CCc1cc ncc1", + "N1 c2ccccc2", + "N N3", + "S CCCC", + "n4cc nc4", + "CCCC N2", + "COc1ccccc1 CC", + "NC c2nc", + "C c2cc3c", + "N c3ccccc32", + "nc4 n3", + "C1CC c2cc", + "c4 Cl", + "c8 cc", + "N2CCCCC2 C", + "2 OCC", + "CCCCCCCC C1", + "CN2 C1", + "no c3C", + "c1cccc2 c1O", + "2 CCO", + "COc1cc 2cc", + "n3 n", + "c4ccccc4 2", + "CC1 COC", + "ccc3 c2o", + "C1 C2C", + "c4ccccc4 O", + "N c4c", + "CCC c2cc", + "c3 cc21", + "C1 NCC", + "C n2cccn2", + "c3ccccc3 S", + "NC1 c1ccc", + "c5ccccc5 3", + "NCc1ccccc1 Cl", + "B 1OC", + "CCn1 c2ccccc2", + "ccc1 Oc1ccc", + "Cl c1ccccc1", + "1 CCNC1", + "c3 c4", + "CCCC Cl", + "10 ccc", + "NCC c3ccc", + "C1 SC", + "c1cn ccc1C", + "N1 c2ccc", + "CN2 CCCN", + "OC c1c", + "N1CC c2ccc", + "ccc2 n1C", + "c1ccc2 ccccc2", + "Cl CCl", + "Cc1c oc", + "4 5", + "CC c2nc", + "CC1 CO1", + "c1 CO", + "CS SC", + "Nc2cc nc", + "NCCN S", + "+]( -", + "c4ccc5 oc6ccccc6", + "4 c5ccccc5", + "OC 3C", + "COc1c ncc", + "CCO c1ccc2nc", + "c8 c7", + "cccc1 S", + "ccc4 ccccc34", + "Cc1cc sc1C", + "C2 c2cccc", + "CCC 4C", + "cc1 OCCC", + "c1n cc2c", + "c3ccccc3 c2c1", + "CC c3cc", + "CCN1 S", + "cc2 ccc", + "c1n o", + "CC1 C1", + "OC2 C1", + "8 O", + "CCNC 4", + "CO c3cccc", + "c2 c1c", + "c6 c7ccccc7", + "c4c3 2", + "CCn1cc nc1", + "Cn1 c2c", + "c1c2ccccc2 c", + "Nc2ccc nc2", + "c1s ccc1Br", + "N c1", + "CC2 CCC2", + "n4c5ccccc5 c5cc", + "C3 CC4", + "CC1 Cc2ccccc2", + "C2 C3C", + "N2CC c3c", + "O c1cc2c", + "CCn1 n", + "cc6 5", + "n2 C1", + "C21 c2ccccc2", + "ccc4 n3", + "c5cccc6c5 oc5ccccc56", + "C c3cnc", + "1O 2", + "CCCN c1ccc", + "nnc1 S", + "COc1ccc2 ccccc2c1", + "ccc1 CNC", + "C1 CCOC2", + "A u", + "ccc3 ccc", + "2 S", + "N O2", + "cc1OC c1ccccc1", + "13 c", + "oc 8ccccc8", + "11 ccccc", + "n3c ncn3", + "1CCCC N1", + "OCCCC OC", + "CCCC1 NC", + "c3 o2", + "CCCCC1 CCC", + "c2c1 CCCC2", + "S CCS", + "C2 c2ccccc2", + "c4ccc5c6ccccc6 n", + "n s2", + "nc1 NC", + "c8ccccc8 n", + "c4 s", + "Cc1 c2c", + "Cc1ccccc1 CC", + "1 c2ccccc2", + "CCCCCCCC Oc1ccc", + "CN1 CCOC", + "CCN CCN", + "c2ccc3 nnc", + "4 NC", + "c nn12", + "Nc2ccccc2 OC", + "CO c2ccccc2C", + "c6 7", + "C2 CS", + "C3 CCC12C", + "CC c1ccccn1", + "CC c1nc2c", + "CCO CCNC", + "o cc", + "Cc1ccccc1 CNC", + "n5 c", + "OC2 CC2", + "n2 nnc", + "2 CC1", + "c4ccc5 cc", + "COc1ccccc1 CN", + "nn3 c2", + "Cc1ccccc1 OCC", + "1 SC", + "CCO N", + "c3nc nc4", + "CN CC3", + "CC2 C4", + "NCCN 2CCOCC2", + "O c4", + "COC 1CN", + "c4ccc5oc6ccccc6 c5c4", + "s c3c", + "NC c1ncc", + "n cc21", + "CNC3 CC3", + "CN 4C", + "c2c1 CCC2", + "c1cn c2ccc", + "CCC c1nn", + "c1s c2nc", + "NCCN 2", + "OCCC S", + "s 6", + "(- [", + "cc nc2", + "C4 CCC4", + "ncc cc12", + "c4 ccccc24", + "c1ccccc1 I", + "N3 CCCN", + "Cc1cc oc1", + "Cc1n sc", + "ccc1 I", + "3 1", + "cc2 NC1", + "C1CO CCN1", + "S N", + "c4ccccc4 C5", + "N Nc1ccc", + "N4CCN CC4", + "2CCN CC2", + "C 9", + "c1nn c2ccccn12", + "Cc1cccc2 c1", + "c1ccc2ncc cc2c1", + "NCC1 CC", + "CCC NC2", + "NC c1cnc", + "C5 CCCCC5", + "Nc1n c2cc", + "cn2 c1", + "Nc1cc ncc1", + "c2c1 N", + "A g", + "CCC c1cccc", + "1CCC c2ccccc21", + "c2cn n3", + "O c2", + "1 CC1", + "CCO c3ccc", + "Nc1ccc2 ccccc2c1", + "1O P", + "CC2 C3", + "C1 NC2", + "s n1", + "C1 c2c", + "2CCC NC2", + "1CO c2ccccc2O1", + "c2cccc3 cccc", + "NCC3 CCCO3", + "c1cn n2c", + "COc1cccc2 c1C", + "COCCC N1C", + "c3cnc nc3", + "Cc3ccccc3 C", + "c2ccccc2 N1", + "csc1 NC", + "c2 CC", + "ncc2 cc", + "NC c1ccncc1", + "c1cc2ccccc2 s1", + "SOO O", + "n cc1F", + "n2 C2CC2", + "N1 CCC1", + "C1 c2cc", + "cc2 c2cc", + "C1 CSC", + "cc1 c32", + "ccccc5 4", + "oc5ccccc5 c4c3", + "1 CCCC1", + "OCCO 5", + "C2 CO", + "OCC3 CC3", + "c3ccc4 o", + "C1 OCC", + "O NC", + "N4 CCCC", + "Nc1ccccc1 Br", + "CCO c2ccccc21", + "c1s ccc1C", + "cc4 c4cc", + "C1CC2 CCC", + "o c1ccccc12", + "Cl c1ccc2c", + "CN2CCN CC2", + "nc2s cc", + "nc n4", + "C c2", + "ccc2 c1C", + "OC N", + "c1n n2c", + "N CCCCCCCC", + "n ccc2c1", + "CCCCC2 1", + "N2 CCSCC2", + "1 CCCCC1", + "NC c2ccccn2", + "OCC1 CO1", + "c3 N", + "c3ccc 3", + "CN1 S", + "o c23", + "O c1ccc2", + "c1cn ccc1", + "N c3", + "C2 CCNC2", + "4 CCCC4", + "c1 c2ccc", + "CCn1 nn", + "C1C c2cc", + "C34 CC5CC", + "Cc1nc n", + "7 CC", + "CN c1ccccc1", + "O c2ccccc2C", + "ccc3 s2", + "1C c2cc", + "cccc 7", + "CCN2 CCCC2", + "C3 NC", + "CC3 CCCO3", + "2 c2cc", + "C n3cc", + "sc5ccccc5 6", + "B 4", + "OC c3cc", + "c2ccccc2 S1", + "2 3O", + "nc2 C1", + "ccccc7 8", + "c3cccc4 c", + "c2 c3nc", + "CCS c1nnc", + "c5ccccc5 c5ccccc5", + "CC1 CCOC1", + "2 c2cccc", + "COC c1c", + "C1 OC2", + "O c4cccc", + "CO CCCO", + "c1n c2cccc", + "NC c3cccnc3", + "CCN 2CC", + "C n2ccc", + "NC c4ccccc4", + "O CCOCCOCCOCCO", + "c3ccc4 c5ccccc5n", + "cc3 o2", + "cccc2 n1", + "C2 c3ccccc3", + "o c3ccccc23", + "c1cc n2", + "M o", + "c2c n3c", + "Cc1s c2nc", + "c2o nc", + "nn3 2", + "H 3", + "n1ccc 2c", + "OCC2 c3ccccc3", + "C5 O", + "n oc1", + "c1o nc", + "c1n c2n", + "C3 CCCN", + "Cn2c ncn2", + "n c3ccccc3", + "nc nc3", + "CC3 CCC2C3", + "CCC1 CCCN", + "CCC1 O2", + "N c2nc3ccc", + "s c2ccccc12", + "cc4 c3c2", + "CN CCCN", + "ncc2 F", + "N5 CCC", + "NCC c1cc", + "c2ccc3 c4ccccc4n", + "5 CCCN5C", + "Cc1nc2ccccc2 c", + "c1ccc2 sc", + "c1ccc2 cc3c", + "c7 6", + "cccc4 Cl", + "OC3 CCCC3", + "NCC c3ccccc3", + "-]) /", + "Br c1cccc", + "ccc1 NS", + "CCc1ccc nc1", + "ccc3 ccccc32", + "OCC1 CC1", + "c5ccccc5 C4", + "cnc1 Cl", + "COc1ccccc1 OCC", + "n5 cc", + "oc6ccccc6 7", + "CN4 CCOCC4", + "8 C", + "NCC1 CCCN", + "N1CCS CC1", + "1 C1", + "COc1cccc 2c", + "cc3 1", + "OC1 2", + "Nc2c ncc", + "nc1 OC", + "CN N", + "NCc1ccccc1 F", + "CC c4ccc", + "CC c4ccccc4", + "ncc3 c2", + "c3 c1O", + "CS C3", + "CC1CCC NC1", + "N3 c4ccccc4", + "O CCCCCCCCCCCCCCCC", + "cc3 n", + "O CCOc1ccc", + "C3 C4", + "S CCO", + "ccc nc34", + "OC2 CCCCO2", + "Cc1n cccc1", + "6 c", + "CCCCC 6" + ] + } +} \ No newline at end of file diff --git a/lstm_chem/trainer.py b/lstm_chem/trainer.py new file mode 100644 index 0000000000000000000000000000000000000000..0ed608aaf01e5a6964280e31650c79cd81530333 --- /dev/null +++ b/lstm_chem/trainer.py @@ -0,0 +1,57 @@ +from glob import glob +import os +from tensorflow.keras.callbacks import ModelCheckpoint, TensorBoard + + +class LSTMChemTrainer(object): + def __init__(self, modeler, train_data_loader, valid_data_loader): + self.model = modeler.model + self.config = modeler.config + self.train_data_loader = train_data_loader + self.valid_data_loader = valid_data_loader + self.callbacks = [] + self.init_callbacks() + + def init_callbacks(self): + self.callbacks.append( + ModelCheckpoint( + filepath=os.path.join( + self.config.checkpoint_dir, + '%s-{epoch:02d}-{val_loss:.2f}.hdf5' % + self.config.exp_name), + monitor=self.config.checkpoint_monitor, + mode=self.config.checkpoint_mode, + save_best_only=self.config.checkpoint_save_best_only, + save_weights_only=self.config.checkpoint_save_weights_only, + verbose=self.config.checkpoint_verbose, + )) + self.callbacks.append( + TensorBoard( + log_dir=self.config.tensorboard_log_dir, + write_graph=self.config.tensorboard_write_graph, + )) + + def train(self): +# history = self.model.fit_generator( + history = self.model.fit( + self.train_data_loader, + steps_per_epoch=self.train_data_loader.__len__(), + epochs=self.config.num_epochs, + verbose=self.config.verbose_training, + validation_data=self.valid_data_loader, + validation_steps=self.valid_data_loader.__len__(), + use_multiprocessing=True, + shuffle=True, + callbacks=self.callbacks) + + last_weight_file = glob( + os.path.join( + f'{self.config.checkpoint_dir}', + f'{self.config.exp_name}-{self.config.num_epochs:02}*.hdf5') + )[0] + + assert os.path.exists(last_weight_file) + self.config.model_weight_filename = last_weight_file + + with open(os.path.join(self.config.exp_dir, 'config.json'), 'w') as f: + f.write(self.config.toJSON(indent=2)) diff --git a/lstm_chem/utils/config.py b/lstm_chem/utils/config.py new file mode 100644 index 0000000000000000000000000000000000000000..fff73595a27233e3b9e4b629427dc949a31dea5b --- /dev/null +++ b/lstm_chem/utils/config.py @@ -0,0 +1,26 @@ +import os +import time +import json +from bunch import Bunch + + +def get_config_from_json(json_file): + with open(json_file, 'r') as config_file: + config_dict = json.load(config_file) + config = Bunch(config_dict) + return config + + +def process_config(json_file): + config = get_config_from_json(json_file) + config.config_file = json_file + config.exp_dir = os.path.join( + 'experiments', time.strftime('%Y-%m-%d/', time.localtime()), + config.exp_name) + config.tensorboard_log_dir = os.path.join( + 'experiments', time.strftime('%Y-%m-%d/', time.localtime()), + config.exp_name, 'logs/') + config.checkpoint_dir = os.path.join( + 'experiments', time.strftime('%Y-%m-%d/', time.localtime()), + config.exp_name, 'checkpoints/') + return config diff --git a/lstm_chem/utils/dirs.py b/lstm_chem/utils/dirs.py new file mode 100644 index 0000000000000000000000000000000000000000..bcd2a49e3e1907bbc0bcf94a82cb819fc5670dd7 --- /dev/null +++ b/lstm_chem/utils/dirs.py @@ -0,0 +1,12 @@ +import os +import sys + + +def create_dirs(dirs): + try: + for dir_ in dirs: + if not os.path.exists(dir_): + os.makedirs(dir_) + except Exception as err: + print(f'Creating directories error: {err}') + sys.exit() diff --git a/lstm_chem/utils/smiles_tokenizer.py b/lstm_chem/utils/smiles_tokenizer.py new file mode 100644 index 0000000000000000000000000000000000000000..f998c4aacfb0ac7207991eddc44a73cf8ed707d8 --- /dev/null +++ b/lstm_chem/utils/smiles_tokenizer.py @@ -0,0 +1,65 @@ +import numpy as np + + +class SmilesTokenizer(object): + def __init__(self): + atoms = [ + 'Li', + 'Na', + 'Al', + 'Si', + 'Cl', + 'Sc', + 'Zn', + 'As', + 'Se', + 'Br', + 'Sn', + 'Te', + 'Cn', + 'H', + 'B', + 'C', + 'N', + 'O', + 'F', + 'P', + 'S', + 'K', + 'V', + 'I' + ] + special = [ + '(', ')', '[', ']', '=', '#', '%', '0', '1', '2', '3', '4', '5', + '6', '7', '8', '9', '+', '-', 'se', 'te', 'c', 'n', 'o', 's' + ] + padding = ['G', 'A', 'E'] + + self.table = sorted(atoms, key=len, reverse=True) + special + padding + self.table_len = len(self.table) + + self.one_hot_dict = {} + for i, symbol in enumerate(self.table): + vec = np.zeros(self.table_len, dtype=np.float32) + vec[i] = 1 + self.one_hot_dict[symbol] = vec + + def tokenize(self, smiles): + N = len(smiles) + i = 0 + token = [] + while (i < N): + for j in range(self.table_len): + symbol = self.table[j] + if symbol == smiles[i:i + len(symbol)]: + token.append(symbol) + i += len(symbol) + break + return token + + def one_hot_encode(self, tokenized_smiles): + result = np.array( + [self.one_hot_dict[symbol] for symbol in tokenized_smiles], + dtype=np.float32) + result = result.reshape(1, result.shape[0], result.shape[1]) + return result diff --git a/lstm_chem/utils/smiles_tokenizer2.py b/lstm_chem/utils/smiles_tokenizer2.py new file mode 100644 index 0000000000000000000000000000000000000000..29575ba2642bab627928d173eba8ecebca141e3d --- /dev/null +++ b/lstm_chem/utils/smiles_tokenizer2.py @@ -0,0 +1,56 @@ +import numpy as np + + +class SmilesTokenizer(object): + def __init__(self): + atoms = [ + 'Al', 'As', 'B', 'Br', 'C', 'Cl', 'F', 'H', 'I', 'K', 'Li', 'N', + 'Na', 'O', 'P', 'S', 'Se', 'Si', 'Te' + ] + special = [ + '(', ')', '[', ']', '=', '#', '%', '0', '1', '2', '3', '4', '5', + '6', '7', '8', '9', '+', '-', 'se', 'te', 'c', 'n', 'o', 's' + ] + padding = ['G', 'A', 'E'] + + self.table = sorted(atoms, key=len, reverse=True) + special + padding + table_len = len(self.table) + + self.table_2_chars = list(filter(lambda x: len(x) == 2, self.table)) + self.table_1_chars = list(filter(lambda x: len(x) == 1, self.table)) + + self.one_hot_dict = {} + for i, symbol in enumerate(self.table): + vec = np.zeros(table_len, dtype=np.float32) + vec[i] = 1 + self.one_hot_dict[symbol] = vec + + def tokenize(self, smiles): + smiles = smiles + ' ' + N = len(smiles) + token = [] + i = 0 + while (i < N): + c1 = smiles[i] + c2 = smiles[i:i + 2] + + if c2 in self.table_2_chars: + token.append(c2) + i += 2 + continue + + if c1 in self.table_1_chars: + token.append(c1) + i += 1 + continue + + i += 1 + + return token + + def one_hot_encode(self, tokenized_smiles): + result = np.array( + [self.one_hot_dict[symbol] for symbol in tokenized_smiles], + dtype=np.float32) + result = result.reshape(1, result.shape[0], result.shape[1]) + return result